KIN_CAT	KIN_ACC_ID	KIN_GENE	SUB_ACC_ID	SUBSTRATE	SUB_MOD_RSD	SUB_MOD_MUT	SUB_MOD_MUT_POS	MUT_TYPE	MUT_DIS	MUT_LOC_MUT	UT_LOC_CEN	SCORE1	SCORE2	PSI_RES	MUT_RES	CUTOFF	INFLUENCE
Other_PEK_HRI_EIF2AK1_ST	P05198	EIF2S1	Q9BQI3	EIF2AK1	S49	M45I	45	Missense	distal	-4	no	7.554	7.556	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	2.464	Up-regulation
Other_PEK_HRI_EIF2AK1_ST	P05198	EIF2S1	Q9BQI3	EIF2AK1	S49	G44C	44	Missense	distal	-5	no	7.554	7.500	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	2.464	Down-regulation
Other_PEK_HRI_EIF2AK1_ST	P05198	EIF2S1	Q9BQI3	EIF2AK1	S52	M45I	45	Missense	distal	-7	no	8.502	8.512	PhosphoSitePlus;EPSD	TCGA;ICGC;COSMIC	2.464	Up-regulation
Other_PEK_HRI_EIF2AK1_ST	P05198	EIF2S1	Q9BQI3	EIF2AK1	S52	R57C	57	Missense	distal	5	no	8.502	8.552	PhosphoSitePlus;EPSD	TCGA;ICGC;COSMIC	2.464	Up-regulation
Other_PEK_HRI_EIF2AK1_ST	P05198	EIF2S1	Q9BQI3	EIF2AK1	S219	L212I	212	Missense	distal	-7	no	2.612	2.625	EPSD	TCGA;ICGC;COSMIC	2.464	Up-regulation
AGC_PKC_PKCd_PRKCD_ST	P18433	PTPRA	Q05655	PRKCD	S187	G184R	184	Missense	distal	-3	no	2.856	8.064	EPSD	TCGA;ICGC;COSMIC	7.604	Gain
AGC_PKC_PKCd_PRKCD_ST	P18433	PTPRA	Q05655	PRKCD	S189	R191H	191	Missense	proximal	2	no	10.453	4.892	EPSD	TCGA	7.604	Loss
AGC_PKC_PKCd_PRKCD_ST	P18433	PTPRA	Q05655	PRKCD	S189	G195C	195	Missense	distal	6	no	10.453	10.436	EPSD	TCGA;ICGC;COSMIC	7.604	Down-regulation
AGC_PKC_PKCd_PRKCD_ST	P18433	PTPRA	Q05655	PRKCD	S189	G184R	184	Missense	distal	-5	no	10.453	10.866	EPSD	TCGA;ICGC;COSMIC	7.604	Up-regulation
AGC_PKC_PKCd_PRKCD_ST	P18433	PTPRA	Q05655	PRKCD	S189	R196H	196	Missense	distal	7	no	10.453	10.366	EPSD	TCGA;ICGC;COSMIC	7.604	Down-regulation
AGC_PKC_PKCd_PRKCD_ST	P18433	PTPRA	Q05655	PRKCD	S193	R191H	191	Missense	proximal	-2	no	7.813	2.838	EPSD	TCGA	7.604	Loss
AGC_PKC_PKCd_PRKCD_ST	P18433	PTPRA	Q05655	PRKCD	S193	G195C	195	Missense	proximal	2	no	7.813	7.266	EPSD	TCGA;ICGC;COSMIC	7.604	Loss
AGC_PKC_PKCd_PRKCD_ST	P18433	PTPRA	Q05655	PRKCD	S193	R196H	196	Missense	distal	3	no	7.813	6.925	EPSD	TCGA;ICGC;COSMIC	7.604	Loss
AGC_PKC_PKCd_PRKCD_ST	P18433	PTPRA	Q05655	PRKCD	S213	T214I	214	Missense	proximal	1	no	8.803	8.716	EPSD	TCGA;COSMIC	7.604	Down-regulation
AGC_PKC_PKCd_PRKCD_ST	P18433	PTPRA	Q05655	PRKCD	T214	T214I	214	Missense	central	0	yes	8.310	0.000	EPSD	TCGA;COSMIC	7.604	Loss
AGC_PKC_PKCd_PRKCD_ST	P18433	PTPRA	Q05655	PRKCD	S542	N547Y	547	Missense	distal	5	no	9.289	9.168	EPSD	TCGA;COSMIC	7.604	Down-regulation
AGC_PKC_PKCd_PRKCD_ST	P18433	PTPRA	Q05655	PRKCD	T672	R674Q	674	Missense	proximal	2	no	8.225	1.436	EPSD	TCGA;ICGC;COSMIC	7.604	Loss
AGC_PKC_PKCd_PRKCD_ST	P18433	PTPRA	Q05655	PRKCD	T672	V673I	673	Missense	proximal	1	no	8.225	8.218	EPSD	TCGA;ICGC;COSMIC;GDSC	7.604	Down-regulation
AGC_PKC_PKCd_PRKCD_ST	P18433	PTPRA	Q05655	PRKCD	T672	L676I	676	Missense	distal	4	no	8.225	8.104	EPSD	TCGA;ICGC	7.604	Down-regulation
AGC_PKC_PKCd_PRKCD_ST	P18433	PTPRA	Q05655	PRKCD	S766	D759G	759	Missense	distal	-7	no	8.609	8.607	EPSD	TCGA;ICGC;COSMIC	7.604	Down-regulation
AGC_PKC_PKCd_PRKCD_ST	P10415	BCL2	Q05655	PRKCD	S24	K17M	17	Missense	distal	-7	no	12.548	12.522	EPSD	TCGA;ICGC;COSMIC	7.604	Down-regulation
AGC_PKC_PKCd_PRKCD_ST	P10415	BCL2	Q05655	PRKCD	S24	Y28H	28	Missense	distal	4	no	12.548	12.801	EPSD	TCGA;ICGC;COSMIC	7.604	Up-regulation
AGC_PKC_PKCd_PRKCD_ST	P10415	BCL2	Q05655	PRKCD	S24	D31N	31	Missense	distal	7	no	12.548	12.541	EPSD	TCGA;ICGC;COSMIC	7.604	Down-regulation
AGC_PKC_PKCd_PRKCD_ST	P10415	BCL2	Q05655	PRKCD	S216	W214C	214	Missense	proximal	-2	no	9.483	9.743	EPSD	TCGA;ICGC;COSMIC	7.604	Up-regulation
AGC_PKC_PKCd_PRKCD_ST	P61978	HNRNPK	Q05655	PRKCD	S276	G269S	269	Missense	distal	-7	no	9.475	9.485	EPSD	TCGA;ICGC;COSMIC	7.604	Up-regulation
AGC_PKC_PKCd_PRKCD_ST	P61978	HNRNPK	Q05655	PRKCD	S276	M283V	283	Missense	distal	7	no	9.475	9.469	EPSD	TCGA;ICGC;COSMIC	7.604	Down-regulation
AGC_PKC_PKCd_PRKCD_ST	P61978	HNRNPK	Q05655	PRKCD	S276	P275S	275	Missense	proximal	-1	no	9.475	9.515	EPSD	TCGA;ICGC;COSMIC	7.604	Up-regulation
AGC_PKC_PKCd_PRKCD_ST	P61978	HNRNPK	Q05655	PRKCD	S276	P274L	274	Missense	proximal	-2	no	9.475	7.805	EPSD	TCGA;ICGC;COSMIC	7.604	Down-regulation
AGC_PKC_PKCd_PRKCD_ST	P61978	HNRNPK	Q05655	PRKCD	S276	R271H	271	Missense	distal	-5	no	9.475	9.139	EPSD	TCGA;ICGC	7.604	Down-regulation
AGC_PKC_PKCd_PRKCD_ST	P61978	HNRNPK	Q05655	PRKCD	S284	M283V	283	Missense	proximal	-1	no	9.561	9.554	EPSD	TCGA;ICGC;COSMIC	7.604	Down-regulation
AGC_PKC_PKCd_PRKCD_ST	P61978	HNRNPK	Q05655	PRKCD	S302	R305Q	305	Missense	distal	3	no	7.752	6.675	PhosphoSitePlus	TCGA;ICGC;COSMIC	7.604	Loss
AGC_PKC_PKCd_PRKCD_ST	P61978	HNRNPK	Q05655	PRKCD	S302	R305W	305	Missense	distal	3	no	7.752	6.330	PhosphoSitePlus	TCGA;ICGC;COSMIC	7.604	Loss
AGC_PKC_PKCd_PRKCD_ST	P61978	HNRNPK	Q05655	PRKCD	S302	A304V	304	Missense	proximal	2	no	7.752	6.605	PhosphoSitePlus	TCGA;ICGC;COSMIC	7.604	Loss
AGC_PKC_PKCd_PRKCD_ST	P61978	HNRNPK	Q05655	PRKCD	S302	G298S	298	Missense	distal	-4	no	7.752	7.600	PhosphoSitePlus	TCGA;ICGC;COSMIC;CCLE	7.604	Loss
AGC_PKC_PKCd_PRKCD_ST	P61978	HNRNPK	Q05655	PRKCD	S417	R414C	414	Missense	distal	-3	no	8.790	3.470	EPSD	TCGA;ICGC;COSMIC;CCLE	7.604	Loss
AGC_PKC_PKCd_PRKCD_ST	P61978	HNRNPK	Q05655	PRKCD	S420	R414C	414	Missense	distal	-6	no	7.194	7.665	EPSD	TCGA;ICGC;COSMIC;CCLE	7.604	Gain
AGC_PKC_PKCd_PRKCD_ST	Q9UQ13	SHOC2	Q05655	PRKCD	S57	A50T	50	Missense	distal	-7	no	9.753	9.754	EPSD	TCGA;ICGC;COSMIC	7.604	Up-regulation
AGC_PKC_PKCd_PRKCD_ST	Q9UQ13	SHOC2	Q05655	PRKCD	S85	A88T	88	Missense	distal	3	no	11.553	11.477	EPSD	TCGA;ICGC;COSMIC	7.604	Down-regulation
AGC_PKC_PKCd_PRKCD_ST	Q9UQ13	SHOC2	Q05655	PRKCD	S85	G80E	80	Missense	distal	-5	no	11.553	11.583	EPSD	TCGA;ICGC	7.604	Up-regulation
AGC_PKC_PKCd_PRKCD_ST	Q9UQ13	SHOC2	Q05655	PRKCD	S86	A88T	88	Missense	proximal	2	no	11.454	10.422	EPSD	TCGA;ICGC;COSMIC	7.604	Down-regulation
AGC_PKC_PKCd_PRKCD_ST	Q9UQ13	SHOC2	Q05655	PRKCD	S86	G80E	80	Missense	distal	-6	no	11.454	11.431	EPSD	TCGA;ICGC	7.604	Down-regulation
AGC_PKC_PKCd_PRKCD_ST	Q9UQ13	SHOC2	Q05655	PRKCD	S102	E99K	99	Missense	distal	-3	no	6.677	11.063	EPSD	TCGA;ICGC;COSMIC	7.604	Gain
AGC_PKC_PKCd_PRKCD_ST	Q9UQ13	SHOC2	Q05655	PRKCD	S297	R301T	301	Missense	distal	4	no	10.402	9.897	EPSD;PhosphoSitePlus	TCGA;COSMIC	7.604	Down-regulation
AGC_PKC_PKCd_PRKCD_ST	Q9UQ13	SHOC2	Q05655	PRKCD	S297	G290D	290	Missense	distal	-7	no	10.402	10.405	EPSD;PhosphoSitePlus	TCGA	7.604	Up-regulation
AGC_PKC_PKCd_PRKCD_ST	P53004	BLVRA	Q05655	PRKCD	S21	G20S	20	Missense	proximal	-1	no	15.400	15.503	EPSD;PhosphoSitePlus	TCGA	7.604	Up-regulation
AGC_PKC_PKCd_PRKCD_ST	P53004	BLVRA	Q05655	PRKCD	S21	R23W	23	Missense	proximal	2	no	15.400	8.727	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	7.604	Down-regulation
AGC_PKC_PKCd_PRKCD_ST	P53004	BLVRA	Q05655	PRKCD	S230	S235C	235	Missense	distal	5	no	8.620	8.284	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	7.604	Down-regulation
AGC_PKC_PKCd_PRKCD_ST	P53004	BLVRA	Q05655	PRKCD	S230	K234N	234	Missense	distal	4	no	8.620	7.975	EPSD;PhosphoSitePlus	TCGA	7.604	Down-regulation
AGC_PKC_PKCd_PRKCD_ST	P53004	BLVRA	Q05655	PRKCD	S230	S237C	237	Missense	distal	7	no	8.620	8.546	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	7.604	Down-regulation
AGC_PKC_PKCd_PRKCD_ST	P53004	BLVRA	Q05655	PRKCD	S230	G236W	236	Missense	distal	6	no	8.620	8.588	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	7.604	Down-regulation
AGC_PKC_PKCd_PRKCD_ST	P53004	BLVRA	Q05655	PRKCD	S230	N226H	226	Missense	distal	-4	no	8.620	8.526	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	7.604	Down-regulation
AGC_PKC_PKCd_PRKCD_ST	P53004	BLVRA	Q05655	PRKCD	S230	H232N	232	Missense	proximal	2	no	8.620	7.630	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	7.604	Down-regulation
AGC_PKC_PKCd_PRKCD_ST	P35611	ADD1	Q05655	PRKCD	S59	P65H	65	Missense	distal	6	no	10.835	10.823	EPSD	TCGA;ICGC;COSMIC	7.604	Down-regulation
AGC_PKC_PKCd_PRKCD_ST	P35611	ADD1	Q05655	PRKCD	S133	S135F	135	Missense	proximal	2	no	7.860	7.803	EPSD	TCGA;ICGC;COSMIC	7.604	Down-regulation
AGC_PKC_PKCd_PRKCD_ST	P35611	ADD1	Q05655	PRKCD	S133	D129N	129	Missense	distal	-4	no	7.860	7.885	EPSD	TCGA;ICGC	7.604	Up-regulation
AGC_PKC_PKCd_PRKCD_ST	P35611	ADD1	Q05655	PRKCD	S353	R354C	354	Missense	proximal	1	no	8.812	8.599	EPSD	TCGA;ICGC;COSMIC	7.604	Down-regulation
AGC_PKC_PKCd_PRKCD_ST	P35611	ADD1	Q05655	PRKCD	S355	R354C	354	Missense	proximal	-1	no	7.607	7.396	EPSD	TCGA;ICGC;COSMIC	7.604	Loss
AGC_PKC_PKCd_PRKCD_ST	P35611	ADD1	Q05655	PRKCD	S436	R442W	442	Missense	distal	6	no	7.747	7.655	EPSD	TCGA;ICGC;COSMIC	7.604	Down-regulation
AGC_PKC_PKCd_PRKCD_ST	P35611	ADD1	Q05655	PRKCD	S436	Q438H	438	Missense	proximal	2	no	7.747	8.976	EPSD	TCGA;ICGC;COSMIC	7.604	Up-regulation
AGC_PKC_PKCd_PRKCD_ST	P35611	ADD1	Q05655	PRKCD	S436	Q438R	438	Missense	proximal	2	no	7.747	14.536	EPSD	TCGA;ICGC;COSMIC	7.604	Up-regulation
AGC_PKC_PKCd_PRKCD_ST	P14598	NCF1	Q05655	PRKCD	T45	Y48C	48	Missense	distal	3	no	9.067	9.127	EPSD	TCGA;ICGC;COSMIC	7.604	Up-regulation
AGC_PKC_PKCd_PRKCD_ST	P14598	NCF1	Q05655	PRKCD	T45	H51Q	51	Missense	distal	6	no	9.067	9.071	EPSD	TCGA;ICGC;COSMIC	7.604	Up-regulation
AGC_PKC_PKCd_PRKCD_ST	P14598	NCF1	Q05655	PRKCD	T45	E49K	49	Missense	distal	4	no	9.067	9.662	EPSD	TCGA;ICGC;COSMIC;GDSC	7.604	Up-regulation
AGC_PKC_PKCd_PRKCD_ST	P14598	NCF1	Q05655	PRKCD	T133	N131K	131	Missense	proximal	-2	no	4.637	9.367	EPSD	TCGA	7.604	Gain
AGC_PKC_PKCd_PRKCD_ST	P14598	NCF1	Q05655	PRKCD	S328	F331S	331	Missense	distal	3	no	17.699	17.918	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	7.604	Up-regulation
AGC_PKC_PKCd_PRKCD_ST	Q16206	ENOX2	Q05655	PRKCD	S240	R237H	237	Missense	distal	-3	no	9.670	5.415	EPSD	TCGA;ICGC;COSMIC	7.604	Loss
AGC_PKC_PKCd_PRKCD_ST	Q16206	ENOX2	Q05655	PRKCD	S240	R237C	237	Missense	distal	-3	no	9.670	4.351	EPSD	TCGA;ICGC;COSMIC;GDSC	7.604	Loss
AGC_PKC_PKCd_PRKCD_ST	Q16206	ENOX2	Q05655	PRKCD	S240	Y247S	247	Missense	distal	7	no	9.670	9.743	EPSD	TCGA	7.604	Up-regulation
AGC_PKC_PKCd_PRKCD_ST	Q16206	ENOX2	Q05655	PRKCD	S240	P239S	239	Missense	proximal	-1	no	9.670	9.711	EPSD	TCGA;ICGC;COSMIC	7.604	Up-regulation
AGC_PKC_PKCd_PRKCD_ST	Q16206	ENOX2	Q05655	PRKCD	S531	S531Y	531	Missense	central	0	yes	8.851	0.000	EPSD	TCGA;ICGC	7.604	Loss
AGC_PKC_PKCd_PRKCD_ST	Q16206	ENOX2	Q05655	PRKCD	S531	S526I	526	Missense	distal	-5	no	8.851	8.659	EPSD	TCGA;ICGC;COSMIC	7.604	Down-regulation
AGC_PKC_PKCd_PRKCD_ST	P19429	TNNI3	Q05655	PRKCD	S23	I19T	19	Missense	distal	-4	no	15.118	14.960	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	7.604	Down-regulation
AGC_PKC_PKCd_PRKCD_ST	P19429	TNNI3	Q05655	PRKCD	S23	Y29H	29	Missense	distal	6	no	15.118	15.142	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	7.604	Up-regulation
AGC_PKC_PKCd_PRKCD_ST	P19429	TNNI3	Q05655	PRKCD	S23	R21C	21	Missense	proximal	-2	no	15.118	9.124	EPSD;PhosphoSitePlus	TCGA	7.604	Down-regulation
AGC_PKC_PKCd_PRKCD_ST	P19429	TNNI3	Q05655	PRKCD	S23	R22H	22	Missense	proximal	-1	no	15.118	14.973	EPSD;PhosphoSitePlus	TCGA;ICGC	7.604	Down-regulation
AGC_PKC_PKCd_PRKCD_ST	P19429	TNNI3	Q05655	PRKCD	S24	I19T	19	Missense	distal	-5	no	14.127	14.294	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	7.604	Up-regulation
AGC_PKC_PKCd_PRKCD_ST	P19429	TNNI3	Q05655	PRKCD	S24	Y29H	29	Missense	distal	5	no	14.127	14.342	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	7.604	Up-regulation
AGC_PKC_PKCd_PRKCD_ST	P19429	TNNI3	Q05655	PRKCD	S24	R21C	21	Missense	distal	-3	no	14.127	8.807	EPSD;PhosphoSitePlus	TCGA	7.604	Down-regulation
AGC_PKC_PKCd_PRKCD_ST	P19429	TNNI3	Q05655	PRKCD	S24	R22H	22	Missense	proximal	-2	no	14.127	9.151	EPSD;PhosphoSitePlus	TCGA;ICGC	7.604	Down-regulation
AGC_PKC_PKCd_PRKCD_ST	P19429	TNNI3	Q05655	PRKCD	S39	K40R	40	Missense	proximal	1	no	10.376	10.359	EPSD	TCGA;COSMIC	7.604	Down-regulation
AGC_PKC_PKCd_PRKCD_ST	P19429	TNNI3	Q05655	PRKCD	S42	K40R	40	Missense	proximal	-2	no	7.033	8.279	EPSD	TCGA;COSMIC	7.604	Gain
AGC_PKC_PKCd_PRKCD_ST	P19429	TNNI3	Q05655	PRKCD	S77	S77N	77	Missense	central	0	yes	15.339	0.000	EPSD	TCGA	7.604	Loss
AGC_PKC_PKCd_PRKCD_ST	P19429	TNNI3	Q05655	PRKCD	T143	R136Q	136	Missense	distal	-7	no	18.627	18.611	PhosphoSitePlus;EPSD	TCGA;COSMIC	7.604	Down-regulation
AGC_PKC_PKCd_PRKCD_ST	P19429	TNNI3	Q05655	PRKCD	T143	R141W	141	Missense	proximal	-2	no	18.627	12.373	PhosphoSitePlus;EPSD	TCGA	7.604	Down-regulation
AGC_PKC_PKCd_PRKCD_ST	P19429	TNNI3	Q05655	PRKCD	T143	R145Q	145	Missense	proximal	2	no	18.627	11.838	PhosphoSitePlus;EPSD	TCGA;COSMIC;GDSC;CCLE	7.604	Down-regulation
AGC_PKC_PKCd_PRKCD_ST	P19429	TNNI3	Q05655	PRKCD	S150	A153V	153	Missense	distal	3	no	8.191	7.959	EPSD	TCGA	7.604	Down-regulation
AGC_PKC_PKCd_PRKCD_ST	P19429	TNNI3	Q05655	PRKCD	S150	R145Q	145	Missense	distal	-5	no	8.191	7.841	EPSD	TCGA;COSMIC;GDSC;CCLE	7.604	Down-regulation
AGC_PKC_PKCd_PRKCD_ST	P19429	TNNI3	Q05655	PRKCD	T181	T181P	181	Missense	central	0	yes	9.017	0.000	EPSD	TCGA;COSMIC	7.604	Loss
AGC_PKC_PKCd_PRKCD_ST	P19429	TNNI3	Q05655	PRKCD	T181	E182D	182	Missense	proximal	1	no	9.017	8.989	EPSD	TCGA;COSMIC	7.604	Down-regulation
AGC_PKC_PKCd_PRKCD_ST	P19429	TNNI3	Q05655	PRKCD	T181	K174N	174	Missense	distal	-7	no	9.017	8.992	EPSD	TCGA;COSMIC	7.604	Down-regulation
AGC_PKC_PKCd_PRKCD_ST	P19429	TNNI3	Q05655	PRKCD	T181	R186W	186	Missense	distal	5	no	9.017	8.288	EPSD	TCGA;COSMIC	7.604	Down-regulation
AGC_PKC_PKCd_PRKCD_ST	P15407	FOSL1	Q05655	PRKCD	S251	R249P	249	Missense	proximal	-2	no	9.698	5.235	EPSD	TCGA;COSMIC	7.604	Loss
AGC_PKC_PKCd_PRKCD_ST	P15407	FOSL1	Q05655	PRKCD	S251	H248N	248	Missense	distal	-3	no	9.698	8.814	EPSD	TCGA;COSMIC	7.604	Down-regulation
AGC_PKC_PKCd_PRKCD_ST	P15407	FOSL1	Q05655	PRKCD	S251	A247T	247	Missense	distal	-4	no	9.698	9.668	EPSD	TCGA;COSMIC	7.604	Down-regulation
AGC_PKC_PKCd_PRKCD_ST	P15407	FOSL1	Q05655	PRKCD	S251	G256R	256	Missense	distal	5	no	9.698	10.142	EPSD	TCGA;COSMIC	7.604	Up-regulation
AGC_PKC_PKCd_PRKCD_ST	P15407	FOSL1	Q05655	PRKCD	S251	R249C	249	Missense	proximal	-2	no	9.698	3.704	EPSD	TCGA;COSMIC	7.604	Loss
AGC_PKC_PKCd_PRKCD_ST	P15407	FOSL1	Q05655	PRKCD	S252	R249P	249	Missense	distal	-3	no	11.747	7.504	EPSD	TCGA;COSMIC	7.604	Loss
AGC_PKC_PKCd_PRKCD_ST	P15407	FOSL1	Q05655	PRKCD	S252	H248N	248	Missense	distal	-4	no	11.747	11.842	EPSD	TCGA;COSMIC	7.604	Up-regulation
AGC_PKC_PKCd_PRKCD_ST	P15407	FOSL1	Q05655	PRKCD	S252	A247T	247	Missense	distal	-5	no	11.747	11.791	EPSD	TCGA;COSMIC	7.604	Up-regulation
AGC_PKC_PKCd_PRKCD_ST	P15407	FOSL1	Q05655	PRKCD	S252	G256R	256	Missense	distal	4	no	11.747	12.415	EPSD	TCGA;COSMIC	7.604	Up-regulation
AGC_PKC_PKCd_PRKCD_ST	P15407	FOSL1	Q05655	PRKCD	S252	R249C	249	Missense	distal	-3	no	11.747	6.428	EPSD	TCGA;COSMIC	7.604	Loss
AGC_PKC_PKCd_PRKCD_ST	P15407	FOSL1	Q05655	PRKCD	S253	G256R	256	Missense	distal	3	no	7.075	8.212	EPSD	TCGA;COSMIC	7.604	Gain
AGC_PKC_PKCd_PRKCD_ST	P15407	FOSL1	Q05655	PRKCD	S254	G256R	256	Missense	proximal	2	no	3.476	9.808	EPSD	TCGA;COSMIC	7.604	Gain
AGC_PKC_PKCd_PRKCD_ST	P15407	FOSL1	Q05655	PRKCD	S259	G256R	256	Missense	distal	-3	no	3.131	8.340	EPSD	TCGA;COSMIC	7.604	Gain
AGC_PKC_PKCd_PRKCD_ST	Q9UBS0	RPS6KB2	Q05655	PRKCD	S410	S410L	410	Missense	central	0	yes	13.029	0.000	EPSD	TCGA;ICGC;COSMIC	7.604	Loss
AGC_PKC_PKCd_PRKCD_ST	Q9UBS0	RPS6KB2	Q05655	PRKCD	S416	R419W	419	Missense	distal	3	no	9.315	7.893	EPSD	TCGA;ICGC;COSMIC	7.604	Down-regulation
AGC_PKC_PKCd_PRKCD_ST	Q9UBS0	RPS6KB2	Q05655	PRKCD	S416	S410L	410	Missense	distal	-6	no	9.315	9.560	EPSD	TCGA;ICGC;COSMIC	7.604	Up-regulation
AGC_PKC_PKCd_PRKCD_ST	Q9UBS0	RPS6KB2	Q05655	PRKCD	S436	P440L	440	Missense	distal	4	no	7.834	7.629	EPSD	TCGA;ICGC;COSMIC;GDSC	7.604	Down-regulation
AGC_PKC_PKCd_PRKCD_ST	Q9H257	CARD9	Q05655	PRKCD	T231	T231M	231	Missense	central	0	yes	16.196	0.000	PhosphoSitePlus	TCGA;ICGC;COSMIC	7.604	Loss
AGC_PKC_PKCd_PRKCD_ST	Q9H257	CARD9	Q05655	PRKCD	T231	A237G	237	Missense	distal	6	no	16.196	16.187	PhosphoSitePlus	TCGA;ICGC;COSMIC	7.604	Down-regulation
AGC_PKC_PKCd_PRKCD_ST	Q9H257	CARD9	Q05655	PRKCD	S303	R309H	309	Missense	distal	6	no	9.149	9.099	EPSD	TCGA	7.604	Down-regulation
AGC_PKC_PKCd_PRKCD_ST	Q9H257	CARD9	Q05655	PRKCD	S303	T300I	300	Missense	distal	-3	no	9.149	8.600	EPSD	TCGA;ICGC;COSMIC	7.604	Down-regulation
AGC_PKC_PKCd_PRKCD_ST	Q9H257	CARD9	Q05655	PRKCD	S431	E428K	428	Missense	distal	-3	no	10.159	14.545	EPSD	TCGA;ICGC;COSMIC	7.604	Up-regulation
AGC_PKC_PKCd_PRKCD_ST	P05107	ITGB2	Q05655	PRKCD	S490	G495R	495	Missense	distal	5	no	7.721	8.164	EPSD	TCGA;ICGC;COSMIC	7.604	Up-regulation
AGC_PKC_PKCd_PRKCD_ST	P05107	ITGB2	Q05655	PRKCD	S496	D500G	500	Missense	distal	4	no	8.090	8.051	EPSD	TCGA;ICGC;COSMIC	7.604	Down-regulation
AGC_PKC_PKCd_PRKCD_ST	P05107	ITGB2	Q05655	PRKCD	S496	R498Q	498	Missense	proximal	2	no	8.090	1.301	EPSD	TCGA;ICGC;COSMIC	7.604	Loss
AGC_PKC_PKCd_PRKCD_ST	P05107	ITGB2	Q05655	PRKCD	S496	G495R	495	Missense	proximal	-1	no	8.090	8.267	EPSD	TCGA;ICGC;COSMIC	7.604	Up-regulation
AGC_PKC_PKCd_PRKCD_ST	P05107	ITGB2	Q05655	PRKCD	S591	R587C	587	Missense	distal	-4	no	8.634	9.069	EPSD	TCGA;ICGC;COSMIC	7.604	Up-regulation
AGC_PKC_PKCd_PRKCD_ST	P05107	ITGB2	Q05655	PRKCD	S591	R586Q	586	Missense	distal	-5	no	8.634	8.283	EPSD	TCGA;ICGC;COSMIC	7.604	Down-regulation
AGC_PKC_PKCd_PRKCD_ST	P05107	ITGB2	Q05655	PRKCD	S591	G594D	594	Missense	distal	3	no	8.634	8.667	EPSD	TCGA;ICGC;COSMIC	7.604	Up-regulation
AGC_PKC_PKCd_PRKCD_ST	P05107	ITGB2	Q05655	PRKCD	S591	R597H	597	Missense	distal	6	no	8.634	8.584	EPSD	TCGA;ICGC;COSMIC	7.604	Down-regulation
AGC_PKC_PKCd_PRKCD_ST	P05107	ITGB2	Q05655	PRKCD	S745	L743R	743	Missense	proximal	-2	no	7.580	13.713	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	7.604	Gain
AGC_PKC_PKCd_PRKCD_ST	Q05655	PRKCD	Q05655	PRKCD	T38	T43P	43	Missense	distal	5	no	8.523	8.652	EPSD	TCGA;ICGC;COSMIC	7.604	Up-regulation
AGC_PKC_PKCd_PRKCD_ST	Q05655	PRKCD	Q05655	PRKCD	T38	A35V	35	Missense	distal	-3	no	8.523	8.061	EPSD	TCGA;ICGC;COSMIC	7.604	Down-regulation
AGC_PKC_PKCd_PRKCD_ST	Q05655	PRKCD	Q05655	PRKCD	T38	E34Q	34	Missense	distal	-4	no	8.523	8.472	EPSD	TCGA;ICGC;COSMIC	7.604	Down-regulation
AGC_PKC_PKCd_PRKCD_ST	Q05655	PRKCD	Q05655	PRKCD	T38	A35T	35	Missense	distal	-3	no	8.523	7.770	EPSD	TCGA;ICGC	7.604	Down-regulation
AGC_PKC_PKCd_PRKCD_ST	Q05655	PRKCD	Q05655	PRKCD	T50	Y52H	52	Missense	proximal	2	no	7.019	9.001	EPSD	TCGA;ICGC;COSMIC	7.604	Gain
AGC_PKC_PKCd_PRKCD_ST	Q05655	PRKCD	Q05655	PRKCD	S130	R132H	132	Missense	proximal	2	no	13.856	8.295	EPSD	TCGA;ICGC;COSMIC	7.604	Down-regulation
AGC_PKC_PKCd_PRKCD_ST	Q05655	PRKCD	Q05655	PRKCD	T295	Q293K	293	Missense	proximal	-2	no	7.050	11.239	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	7.604	Gain
AGC_PKC_PKCd_PRKCD_ST	Q05655	PRKCD	Q05655	PRKCD	S299	R300W	300	Missense	proximal	1	no	13.252	12.971	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	7.604	Down-regulation
AGC_PKC_PKCd_PRKCD_ST	Q05655	PRKCD	Q05655	PRKCD	S299	S302L	302	Missense	distal	3	no	13.252	12.965	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	7.604	Down-regulation
AGC_PKC_PKCd_PRKCD_ST	Q05655	PRKCD	Q05655	PRKCD	S299	Q293K	293	Missense	distal	-6	no	13.252	12.900	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	7.604	Down-regulation
AGC_PKC_PKCd_PRKCD_ST	Q05655	PRKCD	Q05655	PRKCD	S302	S299T	299	Missense	distal	-3	no	9.128	8.610	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	7.604	Down-regulation
AGC_PKC_PKCd_PRKCD_ST	Q05655	PRKCD	Q05655	PRKCD	S302	R300W	300	Missense	proximal	-2	no	9.128	2.874	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	7.604	Loss
AGC_PKC_PKCd_PRKCD_ST	Q05655	PRKCD	Q05655	PRKCD	S302	S302L	302	Missense	central	0	yes	9.128	0.000	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	7.604	Loss
AGC_PKC_PKCd_PRKCD_ST	Q05655	PRKCD	Q05655	PRKCD	S304	S299T	299	Missense	distal	-5	no	8.265	8.240	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	7.604	Down-regulation
AGC_PKC_PKCd_PRKCD_ST	Q05655	PRKCD	Q05655	PRKCD	S304	R300W	300	Missense	distal	-4	no	8.265	8.796	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	7.604	Up-regulation
AGC_PKC_PKCd_PRKCD_ST	Q05655	PRKCD	Q05655	PRKCD	S304	S302L	302	Missense	proximal	-2	no	8.265	6.980	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	7.604	Loss
AGC_PKC_PKCd_PRKCD_ST	Q05655	PRKCD	Q05655	PRKCD	S506	C509R	509	Missense	distal	3	no	9.588	10.862	EPSD	TCGA;ICGC;COSMIC	7.604	Up-regulation
AGC_PKC_PKCd_PRKCD_ST	Q05655	PRKCD	Q05655	PRKCD	S506	T511N	511	Missense	distal	5	no	9.588	9.466	EPSD	TCGA;ICGC;COSMIC	7.604	Down-regulation
AGC_PKC_PKCd_PRKCD_ST	Q05655	PRKCD	Q05655	PRKCD	T507	C509R	509	Missense	proximal	2	no	5.880	12.759	EPSD	TCGA;ICGC;COSMIC	7.604	Gain
AGC_PKC_PKCd_PRKCD_ST	Q05655	PRKCD	Q05655	PRKCD	S559	L556F	556	Missense	distal	-3	no	8.200	8.863	EPSD	TCGA;ICGC	7.604	Up-regulation
AGC_PKC_PKCd_PRKCD_ST	Q05655	PRKCD	Q05655	PRKCD	S626	R628K	628	Missense	proximal	2	no	13.703	12.526	EPSD	TCGA;ICGC;COSMIC	7.604	Down-regulation
AGC_PKC_PKCd_PRKCD_ST	Q05655	PRKCD	Q05655	PRKCD	S631	R628K	628	Missense	distal	-3	no	7.637	6.602	EPSD	TCGA;ICGC;COSMIC	7.604	Loss
AGC_PKC_PKCd_PRKCD_ST	P13796	LCP1	Q05655	PRKCD	S5	A2V	2	Missense	distal	-3	no	9.438	8.976	PhosphoSitePlus	TCGA;ICGC	7.604	Down-regulation
AGC_PKC_PKCd_PRKCD_ST	P13796	LCP1	Q05655	PRKCD	S5	S7P	7	Missense	proximal	2	no	9.438	9.682	PhosphoSitePlus	TCGA;ICGC;COSMIC	7.604	Up-regulation
AGC_PKC_PKCd_PRKCD_ST	P13796	LCP1	Q05655	PRKCD	S5	M11I	11	Missense	distal	6	no	9.438	9.432	PhosphoSitePlus	TCGA;ICGC;COSMIC	7.604	Down-regulation
AGC_PKC_PKCd_PRKCD_ST	P13796	LCP1	Q05655	PRKCD	T89	K88N	88	Missense	proximal	-1	no	7.876	7.694	EPSD	TCGA;ICGC;COSMIC	7.604	Down-regulation
AGC_PKC_PKCd_PRKCD_ST	P13796	LCP1	Q05655	PRKCD	T89	S83G	83	Missense	distal	-6	no	7.876	8.067	EPSD	TCGA;ICGC;COSMIC	7.604	Up-regulation
AGC_PKC_PKCd_PRKCD_ST	P13796	LCP1	Q05655	PRKCD	S296	K294R	294	Missense	proximal	-2	no	7.103	8.349	EPSD	TCGA;ICGC;COSMIC	7.604	Gain
AGC_PKC_PKCd_PRKCD_ST	P13796	LCP1	Q05655	PRKCD	T503	Y502S	502	Missense	proximal	-1	no	9.340	9.486	EPSD	TCGA;COSMIC	7.604	Up-regulation
AGC_PKC_PKCd_PRKCD_ST	P13796	LCP1	Q05655	PRKCD	T503	E508K	508	Missense	distal	5	no	9.340	9.778	EPSD	TCGA	7.604	Up-regulation
AGC_PKC_PKCd_PRKCD_ST	P13796	LCP1	Q05655	PRKCD	S537	P544L	544	Missense	distal	7	no	7.968	7.937	EPSD	TCGA;COSMIC	7.604	Down-regulation
AGC_PKC_PKCd_PRKCD_ST	P13796	LCP1	Q05655	PRKCD	S540	P544L	544	Missense	distal	4	no	7.856	7.651	EPSD	TCGA;COSMIC	7.604	Down-regulation
AGC_PKC_PKCd_PRKCD_ST	P13796	LCP1	Q05655	PRKCD	S547	P544L	544	Missense	distal	-3	no	9.878	8.935	EPSD	TCGA;COSMIC	7.604	Down-regulation
AGC_PKC_PKCd_PRKCD_ST	Q9HBA0	TRPV4	Q05655	PRKCD	S134	K130E	130	Missense	distal	-4	no	9.176	9.568	EPSD	TCGA;ICGC	7.604	Up-regulation
AGC_PKC_PKCd_PRKCD_ST	Q9HBA0	TRPV4	Q05655	PRKCD	S134	P138T	138	Missense	distal	4	no	9.176	9.102	EPSD	TCGA;ICGC;COSMIC	7.604	Down-regulation
AGC_PKC_PKCd_PRKCD_ST	Q9HBA0	TRPV4	Q05655	PRKCD	S134	P132L	132	Missense	proximal	-2	no	9.176	7.506	EPSD	TCGA;ICGC;COSMIC	7.604	Loss
AGC_PKC_PKCd_PRKCD_ST	Q9HBA0	TRPV4	Q05655	PRKCD	S134	P135L	135	Missense	proximal	1	no	9.176	9.101	EPSD	TCGA	7.604	Down-regulation
AGC_PKC_PKCd_PRKCD_ST	Q9HBA0	TRPV4	Q05655	PRKCD	S189	E184K	184	Missense	distal	-5	no	7.627	7.985	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	7.604	Up-regulation
AGC_PKC_PKCd_PRKCD_ST	Q13501	SQSTM1	Q05655	PRKCD	S176	G173R	173	Missense	distal	-3	no	3.612	8.820	EPSD	TCGA;ICGC;COSMIC	7.604	Gain
AGC_PKC_PKCd_PRKCD_ST	Q13501	SQSTM1	Q05655	PRKCD	T269	S266R	266	Missense	distal	-3	no	7.197	11.772	EPSD	TCGA;ICGC	7.604	Gain
AGC_PKC_PKCd_PRKCD_ST	Q13501	SQSTM1	Q05655	PRKCD	S283	S277I	277	Missense	distal	-6	no	7.387	7.656	EPSD	TCGA;ICGC	7.604	Gain
AGC_PKC_PKCd_PRKCD_ST	Q13501	SQSTM1	Q05655	PRKCD	S284	S284A	284	Missense	central	0	yes	8.808	0.000	EPSD	TCGA;ICGC;COSMIC	7.604	Loss
AGC_PKC_PKCd_PRKCD_ST	Q13501	SQSTM1	Q05655	PRKCD	S284	S277G	277	Missense	distal	-7	no	8.808	8.798	EPSD	TCGA;ICGC;COSMIC	7.604	Down-regulation
AGC_PKC_PKCd_PRKCD_ST	Q13501	SQSTM1	Q05655	PRKCD	S284	S277I	277	Missense	distal	-7	no	8.808	8.793	EPSD	TCGA;ICGC	7.604	Down-regulation
AGC_PKC_PKCd_PRKCD_ST	Q13501	SQSTM1	Q05655	PRKCD	S342	E345K	345	Missense	distal	3	no	7.133	8.314	EPSD	TCGA;COSMIC	7.604	Gain
AGC_PKC_PKCd_PRKCD_ST	P05787	KRT8	Q05655	PRKCD	S9	S15F	15	Missense	distal	6	no	8.549	8.522	EPSD	TCGA;ICGC;COSMIC	7.604	Down-regulation
AGC_PKC_PKCd_PRKCD_ST	P05787	KRT8	Q05655	PRKCD	S13	S15F	15	Missense	proximal	2	no	8.045	7.988	EPSD	TCGA;ICGC;COSMIC	7.604	Down-regulation
AGC_PKC_PKCd_PRKCD_ST	P05787	KRT8	Q05655	PRKCD	S21	S15F	15	Missense	distal	-6	no	17.641	17.847	EPSD	TCGA;ICGC;COSMIC	7.604	Up-regulation
AGC_PKC_PKCd_PRKCD_ST	P05787	KRT8	Q05655	PRKCD	S34	S37F	37	Missense	distal	3	no	8.274	8.056	EPSD	TCGA;ICGC;COSMIC	7.604	Down-regulation
AGC_PKC_PKCd_PRKCD_ST	Q02297	NRG1	Q05655	PRKCD	S435	A432V	432	Missense	distal	-3	no	9.417	8.956	EPSD	TCGA;COSMIC	7.604	Down-regulation
AGC_PKC_PKCd_PRKCD_ST	Q02297	NRG1	Q05655	PRKCD	S435	P436L	436	Missense	proximal	1	no	9.417	9.343	EPSD	TCGA;COSMIC	7.604	Down-regulation
AGC_PKC_PKCd_PRKCD_ST	P51398	DAP3	Q05655	PRKCD	S31	H35Y	35	Missense	distal	4	no	9.607	9.353	PhosphoSitePlus;EPSD	TCGA;ICGC;COSMIC	7.604	Down-regulation
AGC_PKC_PKCd_PRKCD_ST	P51398	DAP3	Q05655	PRKCD	S31	Q27H	27	Missense	distal	-4	no	9.607	9.584	PhosphoSitePlus;EPSD	TCGA;ICGC	7.604	Down-regulation
AGC_PKC_PKCd_PRKCD_ST	P51398	DAP3	Q05655	PRKCD	S44	R50H	50	Missense	distal	6	no	8.907	8.857	EPSD	TCGA;ICGC;COSMIC;GDSC;CCLE	7.604	Down-regulation
AGC_PKC_PKCd_PRKCD_ST	P51398	DAP3	Q05655	PRKCD	S44	P45L	45	Missense	proximal	1	no	8.907	8.832	EPSD	TCGA;ICGC;COSMIC	7.604	Down-regulation
AGC_PKC_PKCd_PRKCD_ST	P51398	DAP3	Q05655	PRKCD	S44	Q39H	39	Missense	distal	-5	no	8.907	8.921	EPSD	TCGA;ICGC;COSMIC	7.604	Up-regulation
AGC_PKC_PKCd_PRKCD_ST	P51398	DAP3	Q05655	PRKCD	S215	G219W	219	Missense	distal	4	no	11.775	11.549	EPSD	TCGA;ICGC;COSMIC	7.604	Down-regulation
AGC_PKC_PKCd_PRKCD_ST	P51398	DAP3	Q05655	PRKCD	T216	G219W	219	Missense	distal	3	no	10.214	9.929	EPSD	TCGA;ICGC;COSMIC	7.604	Down-regulation
AGC_PKC_PKCd_PRKCD_ST	P51398	DAP3	Q05655	PRKCD	S251	S252Y	252	Missense	proximal	1	no	10.259	10.142	EPSD	TCGA;ICGC;COSMIC	7.604	Down-regulation
AGC_PKC_PKCd_PRKCD_ST	P51398	DAP3	Q05655	PRKCD	S251	E246Q	246	Missense	distal	-5	no	10.259	10.292	EPSD	TCGA;ICGC;COSMIC	7.604	Up-regulation
AGC_PKC_PKCd_PRKCD_ST	P51398	DAP3	Q05655	PRKCD	T273	R276I	276	Missense	distal	3	no	11.344	10.032	EPSD	TCGA;ICGC;COSMIC	7.604	Down-regulation
AGC_PKC_PKCd_PRKCD_ST	P42224	STAT1	Q05655	PRKCD	S127	Q124R	124	Missense	distal	-3	no	3.173	8.330	EPSD	TCGA;ICGC;COSMIC	7.604	Gain
AGC_PKC_PKCd_PRKCD_ST	P42224	STAT1	Q05655	PRKCD	T373	E370Q	370	Missense	distal	-3	no	11.393	11.656	EPSD	TCGA;ICGC;COSMIC	7.604	Up-regulation
AGC_PKC_PKCd_PRKCD_ST	P42224	STAT1	Q05655	PRKCD	T373	F377C	377	Missense	distal	4	no	11.393	11.212	EPSD	TCGA;ICGC;COSMIC	7.604	Down-regulation
AGC_PKC_PKCd_PRKCD_ST	P42224	STAT1	Q05655	PRKCD	S604	R608W	608	Missense	distal	4	no	9.193	8.299	EPSD	TCGA;ICGC;COSMIC	7.604	Down-regulation
AGC_PKC_PKCd_PRKCD_ST	P42224	STAT1	Q05655	PRKCD	S604	E605D	605	Missense	proximal	1	no	9.193	9.165	EPSD	TCGA;ICGC;COSMIC	7.604	Down-regulation
AGC_PKC_PKCd_PRKCD_ST	P42224	STAT1	Q05655	PRKCD	S604	E609K	609	Missense	distal	5	no	9.193	9.631	EPSD	TCGA;ICGC;COSMIC	7.604	Up-regulation
AGC_PKC_PKCd_PRKCD_ST	P42224	STAT1	Q05655	PRKCD	S604	A611T	611	Missense	distal	7	no	9.193	9.211	EPSD	TCGA	7.604	Up-regulation
AGC_PKC_PKCd_PRKCD_ST	P42224	STAT1	Q05655	PRKCD	S606	R608W	608	Missense	proximal	2	no	9.555	2.882	EPSD	TCGA;ICGC;COSMIC	7.604	Loss
AGC_PKC_PKCd_PRKCD_ST	P42224	STAT1	Q05655	PRKCD	S606	E605D	605	Missense	proximal	-1	no	9.555	9.573	EPSD	TCGA;ICGC;COSMIC	7.604	Up-regulation
AGC_PKC_PKCd_PRKCD_ST	P42224	STAT1	Q05655	PRKCD	S606	E609K	609	Missense	distal	3	no	9.555	10.736	EPSD	TCGA;ICGC;COSMIC	7.604	Up-regulation
AGC_PKC_PKCd_PRKCD_ST	P42224	STAT1	Q05655	PRKCD	S606	A611T	611	Missense	distal	5	no	9.555	9.594	EPSD	TCGA	7.604	Up-regulation
AGC_PKC_PKCd_PRKCD_ST	P42224	STAT1	Q05655	PRKCD	S640	E638K	638	Missense	proximal	-2	no	4.710	9.690	EPSD	TCGA;ICGC;COSMIC	7.604	Gain
AGC_PKC_PKCd_PRKCD_ST	P62753	RPS6	Q05655	PRKCD	T181	R178H	178	Missense	distal	-3	no	10.627	6.372	EPSD	TCGA	7.604	Loss
AGC_PKC_PKCd_PRKCD_ST	P62753	RPS6	Q05655	PRKCD	T181	R183C	183	Missense	proximal	2	no	10.627	3.748	EPSD	TCGA;ICGC;COSMIC;GDSC;CCLE	7.604	Loss
AGC_PKC_PKCd_PRKCD_ST	P62753	RPS6	Q05655	PRKCD	S235	K230N	230	Missense	distal	-5	no	16.067	15.688	PhosphoSitePlus;EPSD	TCGA;ICGC;COSMIC	7.604	Down-regulation
AGC_PKC_PKCd_PRKCD_ST	P62753	RPS6	Q05655	PRKCD	S235	S236C	236	Missense	proximal	1	no	16.067	15.948	PhosphoSitePlus;EPSD	TCGA;ICGC;COSMIC	7.604	Down-regulation
AGC_PKC_PKCd_PRKCD_ST	P62753	RPS6	Q05655	PRKCD	S235	R232H	232	Missense	distal	-3	no	16.067	11.812	PhosphoSitePlus;EPSD	TCGA;ICGC;COSMIC	7.604	Down-regulation
AGC_PKC_PKCd_PRKCD_ST	P62753	RPS6	Q05655	PRKCD	S235	R233I	233	Missense	proximal	-2	no	16.067	9.342	PhosphoSitePlus;EPSD	TCGA;ICGC;COSMIC	7.604	Down-regulation
AGC_PKC_PKCd_PRKCD_ST	P62753	RPS6	Q05655	PRKCD	S235	R232C	232	Missense	distal	-3	no	16.067	10.747	PhosphoSitePlus;EPSD	TCGA;ICGC;COSMIC	7.604	Down-regulation
AGC_PKC_PKCd_PRKCD_ST	P62753	RPS6	Q05655	PRKCD	S236	K230N	230	Missense	distal	-6	no	14.320	14.770	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	7.604	Up-regulation
AGC_PKC_PKCd_PRKCD_ST	P62753	RPS6	Q05655	PRKCD	S236	S236C	236	Missense	central	0	yes	14.320	0.000	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	7.604	Loss
AGC_PKC_PKCd_PRKCD_ST	P62753	RPS6	Q05655	PRKCD	S236	R232H	232	Missense	distal	-4	no	14.320	14.612	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	7.604	Up-regulation
AGC_PKC_PKCd_PRKCD_ST	P62753	RPS6	Q05655	PRKCD	S236	R233I	233	Missense	distal	-3	no	14.320	8.678	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	7.604	Down-regulation
AGC_PKC_PKCd_PRKCD_ST	P62753	RPS6	Q05655	PRKCD	S236	R232C	232	Missense	distal	-4	no	14.320	14.755	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	7.604	Up-regulation
AGC_PKC_PKCd_PRKCD_ST	P62753	RPS6	Q05655	PRKCD	S240	S236C	236	Missense	distal	-4	no	9.107	9.309	EPSD	TCGA;ICGC;COSMIC	7.604	Up-regulation
AGC_PKC_PKCd_PRKCD_ST	P62753	RPS6	Q05655	PRKCD	S240	R233I	233	Missense	distal	-7	no	9.107	9.081	EPSD	TCGA;ICGC;COSMIC	7.604	Down-regulation
AGC_PKC_PKCd_PRKCD_ST	P62753	RPS6	Q05655	PRKCD	T241	S236C	236	Missense	distal	-5	no	12.317	12.114	EPSD	TCGA;ICGC;COSMIC	7.604	Down-regulation
AGC_PKC_PKCd_PRKCD_ST	P62753	RPS6	Q05655	PRKCD	T241	Q248H	248	Missense	distal	7	no	12.317	12.321	EPSD	TCGA;ICGC;COSMIC	7.604	Up-regulation
AGC_PKC_PKCd_PRKCD_ST	Q99808	SLC29A1	Q05655	PRKCD	S269	G267R	267	Missense	proximal	-2	no	3.126	8.890	EPSD	TCGA;ICGC;COSMIC	7.604	Gain
AGC_PKC_PKCd_PRKCD_ST	Q14247	CTTN	Q05655	PRKCD	S109	E103Q	103	Missense	distal	-6	no	7.847	7.780	EPSD	TCGA;ICGC	7.604	Down-regulation
AGC_PKC_PKCd_PRKCD_ST	Q14247	CTTN	Q05655	PRKCD	S109	Q114P	114	Missense	distal	5	no	7.847	7.984	EPSD	TCGA;ICGC;COSMIC	7.604	Up-regulation
AGC_PKC_PKCd_PRKCD_ST	Q14247	CTTN	Q05655	PRKCD	S109	S113L	113	Missense	distal	4	no	7.847	7.680	EPSD	TCGA;ICGC;COSMIC;GDSC;CCLE	7.604	Down-regulation
AGC_PKC_PKCd_PRKCD_ST	Q14247	CTTN	Q05655	PRKCD	S117	G120V	120	Missense	distal	3	no	7.793	7.774	EPSD	TCGA;ICGC;COSMIC	7.604	Down-regulation
AGC_PKC_PKCd_PRKCD_ST	Q14247	CTTN	Q05655	PRKCD	S117	G123S	123	Missense	distal	6	no	7.793	7.819	EPSD	TCGA;ICGC;COSMIC	7.604	Up-regulation
AGC_PKC_PKCd_PRKCD_ST	Q14247	CTTN	Q05655	PRKCD	S117	Q114P	114	Missense	distal	-3	no	7.793	8.707	EPSD	TCGA;ICGC;COSMIC	7.604	Up-regulation
AGC_PKC_PKCd_PRKCD_ST	Q14247	CTTN	Q05655	PRKCD	S117	S113L	113	Missense	distal	-4	no	7.793	7.953	EPSD	TCGA;ICGC;COSMIC;GDSC;CCLE	7.604	Up-regulation
AGC_PKC_PKCd_PRKCD_ST	Q14247	CTTN	Q05655	PRKCD	S117	G122R	122	Missense	distal	5	no	7.793	8.236	EPSD	TCGA;ICGC;COSMIC	7.604	Up-regulation
AGC_PKC_PKCd_PRKCD_ST	Q14247	CTTN	Q05655	PRKCD	T145	G143R	143	Missense	proximal	-2	no	5.937	11.701	EPSD	TCGA;ICGC;COSMIC	7.604	Gain
AGC_PKC_PKCd_PRKCD_ST	Q14247	CTTN	Q05655	PRKCD	S150	E146G	146	Missense	distal	-4	no	13.265	13.284	EPSD	TCGA;ICGC;COSMIC	7.604	Up-regulation
AGC_PKC_PKCd_PRKCD_ST	Q14247	CTTN	Q05655	PRKCD	S150	S155F	155	Missense	distal	5	no	13.265	13.054	EPSD	TCGA;ICGC;COSMIC	7.604	Down-regulation
AGC_PKC_PKCd_PRKCD_ST	Q14247	CTTN	Q05655	PRKCD	S150	G143R	143	Missense	distal	-7	no	13.265	13.287	EPSD	TCGA;ICGC;COSMIC	7.604	Up-regulation
AGC_PKC_PKCd_PRKCD_ST	Q14247	CTTN	Q05655	PRKCD	S187	R189K	189	Missense	proximal	2	no	13.982	12.804	EPSD	TCGA;ICGC;COSMIC	7.604	Down-regulation
AGC_PKC_PKCd_PRKCD_ST	Q14247	CTTN	Q05655	PRKCD	S187	S192F	192	Missense	distal	5	no	13.982	13.771	EPSD	TCGA;ICGC;COSMIC	7.604	Down-regulation
AGC_PKC_PKCd_PRKCD_ST	Q14247	CTTN	Q05655	PRKCD	S187	H185L	185	Missense	proximal	-2	no	13.982	12.824	EPSD	TCGA;ICGC;COSMIC	7.604	Down-regulation
AGC_PKC_PKCd_PRKCD_ST	Q14247	CTTN	Q05655	PRKCD	S224	H222R	222	Missense	proximal	-2	no	12.196	17.172	EPSD	TCGA;ICGC;COSMIC	7.604	Up-regulation
AGC_PKC_PKCd_PRKCD_ST	Q14247	CTTN	Q05655	PRKCD	S224	T219M	219	Missense	distal	-5	no	12.196	12.066	EPSD	TCGA;ICGC;COSMIC	7.604	Down-regulation
AGC_PKC_PKCd_PRKCD_ST	Q14247	CTTN	Q05655	PRKCD	S277	G270S	270	Missense	distal	-7	no	9.333	9.344	EPSD	TCGA;COSMIC	7.604	Up-regulation
AGC_PKC_PKCd_PRKCD_ST	Q14247	CTTN	Q05655	PRKCD	S277	K272R	272	Missense	distal	-5	no	9.333	9.359	EPSD	TCGA;COSMIC	7.604	Up-regulation
AGC_PKC_PKCd_PRKCD_ST	Q14247	CTTN	Q05655	PRKCD	S277	A284V	284	Missense	distal	7	no	9.333	9.295	EPSD	TCGA;COSMIC;CCLE	7.604	Down-regulation
AGC_PKC_PKCd_PRKCD_ST	Q14247	CTTN	Q05655	PRKCD	S282	A284V	284	Missense	proximal	2	no	8.343	7.195	EPSD	TCGA;COSMIC;CCLE	7.604	Loss
AGC_PKC_PKCd_PRKCD_ST	P98082	DAB2	Q05655	PRKCD	S24	K21E	21	Missense	distal	-3	no	12.739	8.353	PhosphoSitePlus	TCGA;ICGC;COSMIC	7.604	Down-regulation
AGC_PKC_PKCd_PRKCD_ST	P98082	DAB2	Q05655	PRKCD	S24	A18G	18	Missense	distal	-6	no	12.739	12.812	PhosphoSitePlus	TCGA;ICGC;COSMIC	7.604	Up-regulation
AGC_PKC_PKCd_PRKCD_ST	P98082	DAB2	Q05655	PRKCD	S24	A22T	22	Missense	proximal	-2	no	12.739	11.586	PhosphoSitePlus	TCGA;ICGC;COSMIC	7.604	Down-regulation
AGC_PKC_PKCd_PRKCD_ST	P98082	DAB2	Q05655	PRKCD	S24	A18V	18	Missense	distal	-6	no	12.739	12.864	PhosphoSitePlus	TCGA;ICGC;COSMIC	7.604	Up-regulation
AGC_PKC_PKCd_PRKCD_ST	P98082	DAB2	Q05655	PRKCD	S24	K29N	29	Missense	distal	5	no	12.739	12.231	PhosphoSitePlus	TCGA;ICGC;COSMIC	7.604	Down-regulation
AGC_PKC_PKCd_PRKCD_ST	P98082	DAB2	Q05655	PRKCD	S249	L250S	250	Missense	proximal	1	no	8.261	8.316	EPSD	TCGA;ICGC	7.604	Up-regulation
AGC_PKC_PKCd_PRKCD_ST	P98082	DAB2	Q05655	PRKCD	S249	D244N	244	Missense	distal	-5	no	8.261	8.238	EPSD	TCGA;ICGC;COSMIC	7.604	Down-regulation
AGC_PKC_PKCd_PRKCD_ST	P98082	DAB2	Q05655	PRKCD	S249	E242G	242	Missense	distal	-7	no	8.261	8.260	EPSD	TCGA	7.604	Down-regulation
AGC_PKC_PKCd_PRKCD_ST	P98082	DAB2	Q05655	PRKCD	S313	S313C	313	Missense	central	0	yes	9.632	0.000	EPSD	TCGA;ICGC;COSMIC	7.604	Loss
AGC_PKC_PKCd_PRKCD_ST	P98082	DAB2	Q05655	PRKCD	S313	S313Y	313	Missense	central	0	yes	9.632	0.000	EPSD	TCGA;ICGC;COSMIC	7.604	Loss
AGC_PKC_PKCd_PRKCD_ST	P98082	DAB2	Q05655	PRKCD	S313	S313F	313	Missense	central	0	yes	9.632	0.000	EPSD	TCGA;ICGC;COSMIC	7.604	Loss
AGC_PKC_PKCd_PRKCD_ST	P98082	DAB2	Q05655	PRKCD	S313	S316Y	316	Missense	distal	3	no	9.632	9.154	EPSD	TCGA;ICGC	7.604	Down-regulation
AGC_PKC_PKCd_PRKCD_ST	P98082	DAB2	Q05655	PRKCD	S390	K392R	392	Missense	proximal	2	no	7.200	8.377	EPSD	TCGA;ICGC;COSMIC	7.604	Gain
AGC_PKC_PKCd_PRKCD_ST	P98082	DAB2	Q05655	PRKCD	S423	H425R	425	Missense	proximal	2	no	3.198	8.759	EPSD	TCGA;COSMIC	7.604	Gain
AGC_PKC_PKCd_PRKCD_ST	P98082	DAB2	Q05655	PRKCD	S427	H425R	425	Missense	proximal	-2	no	3.899	8.875	EPSD	TCGA;COSMIC	7.604	Gain
AGC_PKC_PKCd_PRKCD_ST	P98082	DAB2	Q05655	PRKCD	S436	R441T	441	Missense	distal	5	no	10.180	9.854	EPSD	TCGA;ICGC;COSMIC	7.604	Down-regulation
AGC_PKC_PKCd_PRKCD_ST	P98082	DAB2	Q05655	PRKCD	S436	Q435E	435	Missense	proximal	-1	no	10.180	10.136	EPSD	TCGA;COSMIC	7.604	Down-regulation
AGC_PKC_PKCd_PRKCD_ST	P98082	DAB2	Q05655	PRKCD	S723	P725R	725	Missense	proximal	2	no	7.502	13.320	EPSD	TCGA;COSMIC	7.604	Gain
AGC_PKC_PKCd_PRKCD_ST	P98082	DAB2	Q05655	PRKCD	S742	S745L	745	Missense	distal	3	no	7.927	7.640	EPSD	TCGA;COSMIC	7.604	Down-regulation
AGC_PKC_PKCd_PRKCD_ST	P98082	DAB2	Q05655	PRKCD	S742	S742Y	742	Missense	central	0	yes	7.927	0.000	EPSD	TCGA	7.604	Loss
AGC_PKC_PKCd_PRKCD_ST	P98082	DAB2	Q05655	PRKCD	S742	N736S	736	Missense	distal	-6	no	7.927	7.727	EPSD	TCGA	7.604	Down-regulation
AGC_PKC_PKCd_PRKCD_ST	P98082	DAB2	Q05655	PRKCD	S742	E735Q	735	Missense	distal	-7	no	7.927	7.931	EPSD	TCGA;COSMIC	7.604	Up-regulation
AGC_PKC_PKCd_PRKCD_ST	P98082	DAB2	Q05655	PRKCD	S742	E735D	735	Missense	distal	-7	no	7.927	7.928	EPSD	TCGA;COSMIC;GDSC;CCLE	7.604	Up-regulation
AGC_PKC_PKCd_PRKCD_ST	P98082	DAB2	Q05655	PRKCD	S742	F738L	738	Missense	distal	-4	no	7.927	7.957	EPSD	TCGA;COSMIC	7.604	Up-regulation
AGC_PKC_PKCd_PRKCD_ST	Q9Y2R2	PTPN22	Q05655	PRKCD	S35	K37E	37	Missense	proximal	2	no	18.769	13.014	PhosphoSitePlus	TCGA;ICGC;COSMIC	7.604	Down-regulation
AGC_PKC_PKCd_PRKCD_ST	Q9Y2R2	PTPN22	Q05655	PRKCD	S35	S35Y	35	Missense	central	0	yes	18.769	0.000	PhosphoSitePlus	TCGA;ICGC;COSMIC	7.604	Loss
AGC_PKC_PKCd_PRKCD_ST	Q9Y2R2	PTPN22	Q05655	PRKCD	S35	S35C	35	Missense	central	0	yes	18.769	0.000	PhosphoSitePlus	TCGA;ICGC;COSMIC	7.604	Loss
AGC_PKC_PKCd_PRKCD_ST	Q9Y2R2	PTPN22	Q05655	PRKCD	S35	L31P	31	Missense	distal	-4	no	18.769	18.631	PhosphoSitePlus	TCGA;ICGC;COSMIC	7.604	Down-regulation
AGC_PKC_PKCd_PRKCD_ST	Q9Y2R2	PTPN22	Q05655	PRKCD	S167	C160G	160	Missense	distal	-7	no	9.951	9.955	EPSD	TCGA;ICGC;COSMIC	7.604	Up-regulation
AGC_PKC_PKCd_PRKCD_ST	Q9Y2R2	PTPN22	Q05655	PRKCD	S352	E350K	350	Missense	proximal	-2	no	6.406	11.386	EPSD	TCGA;ICGC;COSMIC	7.604	Gain
AGC_PKC_PKCd_PRKCD_ST	Q9Y2R2	PTPN22	Q05655	PRKCD	S550	E555Q	555	Missense	distal	5	no	7.568	7.611	EPSD	TCGA;ICGC;COSMIC	7.604	Gain
AGC_PKC_PKCd_PRKCD_ST	Q9Y2R2	PTPN22	Q05655	PRKCD	S692	R690C	690	Missense	proximal	-2	no	9.496	3.502	EPSD	TCGA;ICGC;COSMIC	7.604	Loss
AGC_PKC_PKCd_PRKCD_ST	Q9Y2R2	PTPN22	Q05655	PRKCD	S692	P693L	693	Missense	proximal	1	no	9.496	9.421	EPSD	TCGA;ICGC;COSMIC	7.604	Down-regulation
AGC_PKC_PKCd_PRKCD_ST	Q9Y2R2	PTPN22	Q05655	PRKCD	S692	P693S	693	Missense	proximal	1	no	9.496	9.477	EPSD	TCGA;ICGC;COSMIC	7.604	Down-regulation
AGC_PKC_PKCd_PRKCD_ST	Q9Y2R2	PTPN22	Q05655	PRKCD	S751	S749C	749	Missense	proximal	-2	no	11.808	10.663	EPSD	TCGA;ICGC;COSMIC	7.604	Down-regulation
AGC_PKC_PKCd_PRKCD_ST	Q9Y2R2	PTPN22	Q05655	PRKCD	S751	K744Q	744	Missense	distal	-7	no	11.808	11.790	EPSD	TCGA;ICGC;COSMIC	7.604	Down-regulation
AGC_PKC_PKCd_PRKCD_ST	Q9Y2R2	PTPN22	Q05655	PRKCD	S751	S745C	745	Missense	distal	-6	no	11.808	12.078	EPSD	TCGA;ICGC;COSMIC	7.604	Up-regulation
AGC_PKC_PKCd_PRKCD_ST	Q9Y2R2	PTPN22	Q05655	PRKCD	S793	R799S	799	Missense	distal	6	no	10.199	10.166	EPSD	TCGA;COSMIC	7.604	Down-regulation
AGC_PKC_PKCd_PRKCD_ST	Q9Y2R2	PTPN22	Q05655	PRKCD	S793	R799M	799	Missense	distal	6	no	10.199	10.132	EPSD	TCGA;COSMIC	7.604	Down-regulation
AGC_PKC_PKCd_PRKCD_ST	Q15139	PRKD1	Q05655	PRKCD	S153	F159L	159	Missense	distal	6	no	11.018	11.015	EPSD	TCGA;ICGC;COSMIC	7.604	Down-regulation
AGC_PKC_PKCd_PRKCD_ST	Q15139	PRKD1	Q05655	PRKCD	S205	R200M	200	Missense	distal	-5	no	14.171	13.741	EPSD	TCGA;ICGC;COSMIC	7.604	Down-regulation
AGC_PKC_PKCd_PRKCD_ST	Q15139	PRKD1	Q05655	PRKCD	S205	V212A	212	Missense	distal	7	no	14.171	14.209	EPSD	TCGA;ICGC	7.604	Up-regulation
AGC_PKC_PKCd_PRKCD_ST	Q15139	PRKD1	Q05655	PRKCD	S205	R201W	201	Missense	distal	-4	no	14.171	14.703	EPSD	TCGA;ICGC;COSMIC	7.604	Up-regulation
AGC_PKC_PKCd_PRKCD_ST	Q15139	PRKD1	Q05655	PRKCD	S205	V212I	212	Missense	distal	7	no	14.171	14.166	EPSD	TCGA;ICGC;COSMIC	7.604	Down-regulation
AGC_PKC_PKCd_PRKCD_ST	Q15139	PRKD1	Q05655	PRKCD	S397	P398S	398	Missense	proximal	1	no	8.054	8.034	EPSD	TCGA;COSMIC	7.604	Down-regulation
AGC_PKC_PKCd_PRKCD_ST	Q15139	PRKD1	Q05655	PRKCD	S397	A392G	392	Missense	distal	-5	no	8.054	7.984	EPSD	TCGA;COSMIC	7.604	Down-regulation
AGC_PKC_PKCd_PRKCD_ST	Q15139	PRKD1	Q05655	PRKCD	S397	P398L	398	Missense	proximal	1	no	8.054	7.979	EPSD	TCGA;COSMIC	7.604	Down-regulation
AGC_PKC_PKCd_PRKCD_ST	Q15139	PRKD1	Q05655	PRKCD	S412	K414N	414	Missense	proximal	2	no	8.277	2.903	EPSD;PhosphoSitePlus	TCGA	7.604	Loss
AGC_PKC_PKCd_PRKCD_ST	Q15139	PRKD1	Q05655	PRKCD	S412	L406I	406	Missense	distal	-6	no	8.277	8.300	EPSD;PhosphoSitePlus	TCGA;COSMIC	7.604	Up-regulation
AGC_PKC_PKCd_PRKCD_ST	Q15139	PRKD1	Q05655	PRKCD	S420	K414N	414	Missense	distal	-6	no	11.256	11.707	EPSD	TCGA	7.604	Up-regulation
AGC_PKC_PKCd_PRKCD_ST	Q15139	PRKD1	Q05655	PRKCD	S421	K414N	414	Missense	distal	-7	no	10.023	9.998	EPSD	TCGA	7.604	Down-regulation
AGC_PKC_PKCd_PRKCD_ST	Q15139	PRKD1	Q05655	PRKCD	S738	R740Q	740	Missense	proximal	2	no	8.804	2.015	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	7.604	Loss
AGC_PKC_PKCd_PRKCD_ST	Q15139	PRKD1	Q05655	PRKCD	S738	R732Q	732	Missense	distal	-6	no	8.804	9.107	EPSD;PhosphoSitePlus	TCGA;COSMIC	7.604	Up-regulation
AGC_PKC_PKCd_PRKCD_ST	Q15139	PRKD1	Q05655	PRKCD	S738	R732L	732	Missense	distal	-6	no	8.804	9.251	EPSD;PhosphoSitePlus	TCGA;COSMIC	7.604	Up-regulation
AGC_PKC_PKCd_PRKCD_ST	Q15139	PRKD1	Q05655	PRKCD	S738	R732W	732	Missense	distal	-6	no	8.804	9.397	EPSD;PhosphoSitePlus	TCGA;COSMIC	7.604	Up-regulation
AGC_PKC_PKCd_PRKCD_ST	Q15139	PRKD1	Q05655	PRKCD	S742	R740Q	740	Missense	proximal	-2	no	9.075	3.640	PhosphoSitePlus;EPSD	TCGA;ICGC;COSMIC	7.604	Loss
AGC_PKC_PKCd_PRKCD_ST	Q15139	PRKD1	Q05655	PRKCD	S742	P747T	747	Missense	distal	5	no	9.075	8.946	PhosphoSitePlus;EPSD	TCGA;COSMIC	7.604	Down-regulation
AGC_PKC_PKCd_PRKCD_ST	Q15139	PRKD1	Q05655	PRKCD	S742	A748S	748	Missense	distal	6	no	9.075	9.093	PhosphoSitePlus;EPSD	TCGA;COSMIC	7.604	Up-regulation
AGC_PKC_PKCd_PRKCD_ST	Q15139	PRKD1	Q05655	PRKCD	S742	T746A	746	Missense	distal	4	no	9.075	9.043	PhosphoSitePlus;EPSD	TCGA	7.604	Down-regulation
AGC_PKC_PKCd_PRKCD_ST	Q15139	PRKD1	Q05655	PRKCD	S829	V822L	822	Missense	distal	-7	no	11.806	11.807	EPSD	TCGA;COSMIC	7.604	Up-regulation
AGC_PKC_PKCd_PRKCD_ST	Q15139	PRKD1	Q05655	PRKCD	S829	R827H	827	Missense	proximal	-2	no	11.806	6.830	EPSD	TCGA;COSMIC	7.604	Loss
AGC_PKC_PKCd_PRKCD_ST	Q15139	PRKD1	Q05655	PRKCD	S829	H836N	836	Missense	distal	7	no	11.806	11.780	EPSD	TCGA;COSMIC	7.604	Down-regulation
AGC_PKC_PKCd_PRKCD_ST	Q15139	PRKD1	Q05655	PRKCD	S829	H836L	836	Missense	distal	7	no	11.806	11.770	EPSD	TCGA;COSMIC	7.604	Down-regulation
AGC_PKC_PKCd_PRKCD_ST	Q15139	PRKD1	Q05655	PRKCD	S829	R827C	827	Missense	proximal	-2	no	11.806	5.812	EPSD	TCGA;COSMIC	7.604	Loss
AGC_PKC_PKCd_PRKCD_ST	Q15139	PRKD1	Q05655	PRKCD	S829	K826N	826	Missense	distal	-3	no	11.806	7.702	EPSD	TCGA	7.604	Down-regulation
AGC_PKC_PKCd_PRKCD_ST	Q15139	PRKD1	Q05655	PRKCD	S890	S888R	888	Missense	proximal	-2	no	5.563	10.411	EPSD	TCGA;COSMIC	7.604	Gain
AGC_PKC_PKCd_PRKCD_ST	P05230	FGF1	Q05655	PRKCD	S131	R137W	137	Missense	distal	6	no	12.592	12.500	PhosphoSitePlus	TCGA;ICGC;COSMIC	7.604	Down-regulation
AGC_PKC_PKCd_PRKCD_ST	P05230	FGF1	Q05655	PRKCD	S131	R137Q	137	Missense	distal	6	no	12.592	12.545	PhosphoSitePlus	TCGA;ICGC;COSMIC	7.604	Down-regulation
AGC_PKC_PKCd_PRKCD_ST	P17405	SMPD1	Q05655	PRKCD	S7	P2S	2	Missense	distal	-5	no	8.709	8.718	EPSD	TCGA;ICGC;COSMIC	7.604	Up-regulation
AGC_PKC_PKCd_PRKCD_ST	P28329	CHAT	Q05655	PRKCD	T373	D379Y	379	Missense	distal	6	no	8.955	8.935	EPSD	TCGA;COSMIC	7.604	Down-regulation
AGC_PKC_PKCd_PRKCD_ST	P28329	CHAT	Q05655	PRKCD	T373	S377L	377	Missense	distal	4	no	8.955	8.789	EPSD	TCGA;COSMIC	7.604	Down-regulation
AGC_PKC_PKCd_PRKCD_ST	P28329	CHAT	Q05655	PRKCD	S377	D379Y	379	Missense	proximal	2	no	8.071	6.994	EPSD	TCGA;COSMIC	7.604	Loss
AGC_PKC_PKCd_PRKCD_ST	P28329	CHAT	Q05655	PRKCD	S377	S377L	377	Missense	central	0	yes	8.071	0.000	EPSD	TCGA;COSMIC	7.604	Loss
AGC_PKC_PKCd_PRKCD_ST	P28329	CHAT	Q05655	PRKCD	S464	H460L	460	Missense	distal	-4	no	9.423	9.523	EPSD	TCGA;COSMIC	7.604	Up-regulation
AGC_PKC_PKCd_PRKCD_ST	P28329	CHAT	Q05655	PRKCD	S464	L457M	457	Missense	distal	-7	no	9.423	9.422	EPSD	TCGA;COSMIC	7.604	Down-regulation
AGC_PKC_PKCd_PRKCD_ST	P28329	CHAT	Q05655	PRKCD	S464	R470Q	470	Missense	distal	6	no	9.423	9.376	EPSD	TCGA;COSMIC	7.604	Down-regulation
AGC_PKC_PKCd_PRKCD_ST	P28329	CHAT	Q05655	PRKCD	S464	R466K	466	Missense	proximal	2	no	9.423	8.246	EPSD	TCGA;COSMIC	7.604	Down-regulation
AGC_PKC_PKCd_PRKCD_ST	P28329	CHAT	Q05655	PRKCD	S473	V474I	474	Missense	proximal	1	no	8.924	8.916	EPSD	TCGA;COSMIC;CCLE	7.604	Down-regulation
AGC_PKC_PKCd_PRKCD_ST	P28329	CHAT	Q05655	PRKCD	S473	S473Y	473	Missense	central	0	yes	8.924	0.000	EPSD	TCGA;COSMIC	7.604	Loss
AGC_PKC_PKCd_PRKCD_ST	P28329	CHAT	Q05655	PRKCD	S473	P478R	478	Missense	distal	5	no	8.924	9.121	EPSD	TCGA;COSMIC	7.604	Up-regulation
AGC_PKC_PKCd_PRKCD_ST	P28329	CHAT	Q05655	PRKCD	S473	P478H	478	Missense	distal	5	no	8.924	8.769	EPSD	TCGA;COSMIC	7.604	Down-regulation
AGC_PKC_PKCd_PRKCD_ST	P28329	CHAT	Q05655	PRKCD	S473	R470Q	470	Missense	distal	-3	no	8.924	3.767	EPSD	TCGA;COSMIC	7.604	Loss
AGC_PKC_PKCd_PRKCD_ST	P28329	CHAT	Q05655	PRKCD	S473	R466K	466	Missense	distal	-7	no	8.924	8.927	EPSD	TCGA;COSMIC	7.604	Up-regulation
AGC_PKC_PKCd_PRKCD_ST	P28329	CHAT	Q05655	PRKCD	S473	E476K	476	Missense	distal	3	no	8.924	10.105	EPSD	TCGA;COSMIC	7.604	Up-regulation
AGC_PKC_PKCd_PRKCD_ST	P28329	CHAT	Q05655	PRKCD	S558	A557V	557	Missense	proximal	-1	no	9.671	9.622	EPSD	TCGA;COSMIC	7.604	Down-regulation
AGC_PKC_PKCd_PRKCD_ST	P28329	CHAT	Q05655	PRKCD	S558	P552L	552	Missense	distal	-6	no	9.671	9.840	EPSD	TCGA;COSMIC	7.604	Up-regulation
AGC_PKC_PKCd_PRKCD_ST	P28329	CHAT	Q05655	PRKCD	S558	S556R	556	Missense	proximal	-2	no	9.671	14.519	EPSD	TCGA;COSMIC	7.604	Up-regulation
AGC_PKC_PKCd_PRKCD_ST	P04637	TP53	Q05655	PRKCD	S99	G105C	105	Missense	distal	6	no	8.382	8.366	EPSD	TCGA;ICGC;COSMIC;GDSC	7.604	Down-regulation
AGC_PKC_PKCd_PRKCD_ST	P04637	TP53	Q05655	PRKCD	S99	S106R	106	Missense	distal	7	no	8.382	8.446	EPSD	TCGA;ICGC;COSMIC;GDSC;CCLE	7.604	Up-regulation
AGC_PKC_PKCd_PRKCD_ST	P04637	TP53	Q05655	PRKCD	S99	G105R	105	Missense	distal	6	no	8.382	8.442	EPSD	TCGA;ICGC;COSMIC;CCLE	7.604	Up-regulation
AGC_PKC_PKCd_PRKCD_ST	P04637	TP53	Q05655	PRKCD	S99	G105V	105	Missense	distal	6	no	8.382	8.374	EPSD	TCGA;ICGC;COSMIC	7.604	Down-regulation
AGC_PKC_PKCd_PRKCD_ST	P04637	TP53	Q05655	PRKCD	S99	G105D	105	Missense	distal	6	no	8.382	8.388	EPSD	TCGA;ICGC;COSMIC	7.604	Up-regulation
AGC_PKC_PKCd_PRKCD_ST	P04637	TP53	Q05655	PRKCD	S99	G105S	105	Missense	distal	6	no	8.382	8.409	EPSD	TCGA;ICGC;COSMIC	7.604	Up-regulation
AGC_PKC_PKCd_PRKCD_ST	P04637	TP53	Q05655	PRKCD	S99	V97D	97	Missense	proximal	-2	no	8.382	8.272	EPSD	TCGA;ICGC;COSMIC	7.604	Down-regulation
AGC_PKC_PKCd_PRKCD_ST	P04637	TP53	Q05655	PRKCD	S99	P92S	92	Missense	distal	-7	no	8.382	8.383	EPSD	TCGA;ICGC	7.604	Up-regulation
AGC_PKC_PKCd_PRKCD_ST	P04637	TP53	Q05655	PRKCD	S149	P151R	151	Missense	proximal	2	no	2.096	7.914	EPSD	TCGA;ICGC;COSMIC	7.604	Gain
AGC_PKC_PKCd_PRKCD_ST	P04637	TP53	Q05655	PRKCD	S183	H179R	179	Missense	distal	-4	no	7.852	7.560	EPSD	TCGA;ICGC;COSMIC;GDSC;CCLE	7.604	Loss
AGC_PKC_PKCd_PRKCD_ST	P04637	TP53	Q05655	PRKCD	S183	C176F	176	Missense	distal	-7	no	7.852	7.856	EPSD	TCGA;ICGC;COSMIC;GDSC;CCLE	7.604	Up-regulation
AGC_PKC_PKCd_PRKCD_ST	P04637	TP53	Q05655	PRKCD	S183	R181H	181	Missense	proximal	-2	no	7.852	2.876	EPSD	TCGA;ICGC;COSMIC;CCLE	7.604	Loss
AGC_PKC_PKCd_PRKCD_ST	P04637	TP53	Q05655	PRKCD	S183	G187S	187	Missense	distal	4	no	7.852	8.050	EPSD	TCGA;ICGC;COSMIC	7.604	Up-regulation
AGC_PKC_PKCd_PRKCD_ST	P04637	TP53	Q05655	PRKCD	S183	H179Y	179	Missense	distal	-4	no	7.852	8.013	EPSD	TCGA;ICGC;COSMIC	7.604	Up-regulation
AGC_PKC_PKCd_PRKCD_ST	P04637	TP53	Q05655	PRKCD	S183	C176Y	176	Missense	distal	-7	no	7.852	7.851	EPSD	TCGA;ICGC;COSMIC;GDSC;CCLE	7.604	Down-regulation
AGC_PKC_PKCd_PRKCD_ST	P04637	TP53	Q05655	PRKCD	S183	P190L	190	Missense	distal	7	no	7.852	7.822	EPSD	TCGA;ICGC;COSMIC;CCLE	7.604	Down-regulation
AGC_PKC_PKCd_PRKCD_ST	P04637	TP53	Q05655	PRKCD	S183	P177S	177	Missense	distal	-6	no	7.852	7.775	EPSD	TCGA;ICGC;COSMIC	7.604	Down-regulation
AGC_PKC_PKCd_PRKCD_ST	P04637	TP53	Q05655	PRKCD	S183	H178Q	178	Missense	distal	-5	no	7.852	7.838	EPSD	TCGA;ICGC;COSMIC	7.604	Down-regulation
AGC_PKC_PKCd_PRKCD_ST	P04637	TP53	Q05655	PRKCD	S183	E180K	180	Missense	distal	-3	no	7.852	12.237	EPSD	TCGA;ICGC;COSMIC;CCLE	7.604	Up-regulation
AGC_PKC_PKCd_PRKCD_ST	P04637	TP53	Q05655	PRKCD	S183	C176S	176	Missense	distal	-7	no	7.852	7.866	EPSD	TCGA;ICGC;COSMIC;GDSC;CCLE	7.604	Up-regulation
AGC_PKC_PKCd_PRKCD_ST	P04637	TP53	Q05655	PRKCD	S183	H179N	179	Missense	distal	-4	no	7.852	7.946	EPSD	TCGA;ICGC;COSMIC	7.604	Up-regulation
AGC_PKC_PKCd_PRKCD_ST	P04637	TP53	Q05655	PRKCD	S183	H179P	179	Missense	distal	-4	no	7.852	7.813	EPSD	TCGA;ICGC;COSMIC	7.604	Down-regulation
AGC_PKC_PKCd_PRKCD_ST	P04637	TP53	Q05655	PRKCD	S183	H179L	179	Missense	distal	-4	no	7.852	7.952	EPSD	TCGA;ICGC;COSMIC	7.604	Up-regulation
AGC_PKC_PKCd_PRKCD_ST	P04637	TP53	Q05655	PRKCD	S183	H179D	179	Missense	distal	-4	no	7.852	7.921	EPSD	TCGA;ICGC;COSMIC;GDSC;CCLE	7.604	Up-regulation
AGC_PKC_PKCd_PRKCD_ST	P04637	TP53	Q05655	PRKCD	S183	P190R	190	Missense	distal	7	no	7.852	7.944	EPSD	TCGA;ICGC;COSMIC	7.604	Up-regulation
AGC_PKC_PKCd_PRKCD_ST	P04637	TP53	Q05655	PRKCD	S183	P177R	177	Missense	distal	-6	no	7.852	7.575	EPSD	TCGA;ICGC;COSMIC	7.604	Loss
AGC_PKC_PKCd_PRKCD_ST	P04637	TP53	Q05655	PRKCD	S183	P177H	177	Missense	distal	-6	no	7.852	7.876	EPSD	TCGA;ICGC;COSMIC	7.604	Up-regulation
AGC_PKC_PKCd_PRKCD_ST	P04637	TP53	Q05655	PRKCD	S183	C176W	176	Missense	distal	-7	no	7.852	7.844	EPSD	TCGA;ICGC;COSMIC;GDSC;CCLE	7.604	Down-regulation
AGC_PKC_PKCd_PRKCD_ST	P04637	TP53	Q05655	PRKCD	S183	H179Q	179	Missense	distal	-4	no	7.852	7.875	EPSD	TCGA;ICGC;COSMIC;GDSC;CCLE	7.604	Up-regulation
AGC_PKC_PKCd_PRKCD_ST	P04637	TP53	Q05655	PRKCD	S183	P177T	177	Missense	distal	-6	no	7.852	7.816	EPSD	TCGA;ICGC;COSMIC;GDSC;CCLE	7.604	Down-regulation
AGC_PKC_PKCd_PRKCD_ST	P04637	TP53	Q05655	PRKCD	S183	R181P	181	Missense	proximal	-2	no	7.852	3.389	EPSD	TCGA;ICGC;COSMIC;CCLE	7.604	Loss
AGC_PKC_PKCd_PRKCD_ST	P04637	TP53	Q05655	PRKCD	S183	C176R	176	Missense	distal	-7	no	7.852	7.877	EPSD	TCGA;ICGC;COSMIC	7.604	Up-regulation
AGC_PKC_PKCd_PRKCD_ST	P04637	TP53	Q05655	PRKCD	S183	R181C	181	Missense	proximal	-2	no	7.852	1.858	EPSD	TCGA;ICGC;COSMIC;GDSC;CCLE	7.604	Loss
AGC_PKC_PKCd_PRKCD_ST	P04637	TP53	Q05655	PRKCD	S183	P177L	177	Missense	distal	-6	no	7.852	8.021	EPSD	TCGA;ICGC;COSMIC;GDSC;CCLE	7.604	Up-regulation
AGC_PKC_PKCd_PRKCD_ST	P04637	TP53	Q05655	PRKCD	T211	R213Q	213	Missense	proximal	2	no	12.679	5.889	EPSD	TCGA;ICGC;COSMIC;GDSC;CCLE	7.604	Loss
AGC_PKC_PKCd_PRKCD_ST	P04637	TP53	Q05655	PRKCD	T211	E204Q	204	Missense	distal	-7	no	12.679	12.683	EPSD	TCGA;ICGC;COSMIC	7.604	Up-regulation
AGC_PKC_PKCd_PRKCD_ST	P04637	TP53	Q05655	PRKCD	T211	D208N	208	Missense	distal	-3	no	12.679	12.579	EPSD	TCGA;ICGC;COSMIC	7.604	Down-regulation
AGC_PKC_PKCd_PRKCD_ST	P04637	TP53	Q05655	PRKCD	T211	H214R	214	Missense	distal	3	no	12.679	13.567	EPSD	TCGA;ICGC;COSMIC;GDSC;CCLE	7.604	Up-regulation
AGC_PKC_PKCd_PRKCD_ST	P04637	TP53	Q05655	PRKCD	T211	V218E	218	Missense	distal	7	no	12.679	12.698	EPSD	TCGA;ICGC;COSMIC	7.604	Up-regulation
AGC_PKC_PKCd_PRKCD_ST	P04637	TP53	Q05655	PRKCD	T211	S215I	215	Missense	distal	4	no	12.679	12.391	EPSD	TCGA;ICGC;COSMIC;GDSC;CCLE	7.604	Down-regulation
AGC_PKC_PKCd_PRKCD_ST	P04637	TP53	Q05655	PRKCD	T211	V216M	216	Missense	distal	5	no	12.679	12.677	EPSD	TCGA;ICGC;COSMIC;GDSC;CCLE	7.604	Down-regulation
AGC_PKC_PKCd_PRKCD_ST	P04637	TP53	Q05655	PRKCD	T211	Y205C	205	Missense	distal	-6	no	12.679	12.681	EPSD	TCGA;ICGC;COSMIC;GDSC;CCLE	7.604	Up-regulation
AGC_PKC_PKCd_PRKCD_ST	P04637	TP53	Q05655	PRKCD	T211	Y205N	205	Missense	distal	-6	no	12.679	12.611	EPSD	TCGA;ICGC;COSMIC	7.604	Down-regulation
AGC_PKC_PKCd_PRKCD_ST	P04637	TP53	Q05655	PRKCD	T211	S215N	215	Missense	distal	4	no	12.679	12.495	EPSD	TCGA;ICGC;COSMIC;GDSC;CCLE	7.604	Down-regulation
AGC_PKC_PKCd_PRKCD_ST	P04637	TP53	Q05655	PRKCD	T211	T211I	211	Missense	central	0	yes	12.679	0.000	EPSD	TCGA;ICGC;COSMIC;CCLE	7.604	Loss
AGC_PKC_PKCd_PRKCD_ST	P04637	TP53	Q05655	PRKCD	T211	V216G	216	Missense	distal	5	no	12.679	12.721	EPSD	TCGA;ICGC;COSMIC	7.604	Up-regulation
AGC_PKC_PKCd_PRKCD_ST	P04637	TP53	Q05655	PRKCD	T211	R213L	213	Missense	proximal	2	no	12.679	5.801	EPSD	TCGA;ICGC;COSMIC;GDSC;CCLE	7.604	Loss
AGC_PKC_PKCd_PRKCD_ST	P04637	TP53	Q05655	PRKCD	T211	V216E	216	Missense	distal	5	no	12.679	12.788	EPSD	TCGA;ICGC;COSMIC	7.604	Up-regulation
AGC_PKC_PKCd_PRKCD_ST	P04637	TP53	Q05655	PRKCD	T211	R209K	209	Missense	proximal	-2	no	12.679	11.433	EPSD	TCGA;COSMIC	7.604	Down-regulation
AGC_PKC_PKCd_PRKCD_ST	P04637	TP53	Q05655	PRKCD	T211	V218G	218	Missense	distal	7	no	12.679	12.698	EPSD	TCGA;ICGC;COSMIC	7.604	Up-regulation
AGC_PKC_PKCd_PRKCD_ST	P04637	TP53	Q05655	PRKCD	T211	R213P	213	Missense	proximal	2	no	12.679	6.860	EPSD	TCGA;ICGC;COSMIC	7.604	Loss
AGC_PKC_PKCd_PRKCD_ST	P04637	TP53	Q05655	PRKCD	T211	H214L	214	Missense	distal	3	no	12.679	12.423	EPSD	TCGA;ICGC;COSMIC	7.604	Down-regulation
AGC_PKC_PKCd_PRKCD_ST	P04637	TP53	Q05655	PRKCD	T211	Y205H	205	Missense	distal	-6	no	12.679	12.512	EPSD	TCGA;ICGC;COSMIC;CCLE	7.604	Down-regulation
AGC_PKC_PKCd_PRKCD_ST	P04637	TP53	Q05655	PRKCD	T211	V216L	216	Missense	distal	5	no	12.679	12.746	EPSD	TCGA;ICGC;COSMIC;GDSC;CCLE	7.604	Up-regulation
AGC_PKC_PKCd_PRKCD_ST	P04637	TP53	Q05655	PRKCD	T211	D208G	208	Missense	distal	-3	no	12.679	12.510	EPSD	TCGA;ICGC;COSMIC	7.604	Down-regulation
AGC_PKC_PKCd_PRKCD_ST	P04637	TP53	Q05655	PRKCD	T211	Y205S	205	Missense	distal	-6	no	12.679	12.411	EPSD	TCGA;ICGC;COSMIC	7.604	Down-regulation
AGC_PKC_PKCd_PRKCD_ST	P04637	TP53	Q05655	PRKCD	T211	S215G	215	Missense	distal	4	no	12.679	12.481	EPSD	TCGA;ICGC;COSMIC;GDSC;CCLE	7.604	Down-regulation
AGC_PKC_PKCd_PRKCD_ST	P04637	TP53	Q05655	PRKCD	T211	R209S	209	Missense	proximal	-2	no	12.679	7.830	EPSD	TCGA;ICGC;COSMIC	7.604	Down-regulation
AGC_PKC_PKCd_PRKCD_ST	P04637	TP53	Q05655	PRKCD	T211	R213G	213	Missense	proximal	2	no	12.679	6.347	EPSD	TCGA;ICGC;COSMIC	7.604	Loss
AGC_PKC_PKCd_PRKCD_ST	P04637	TP53	Q05655	PRKCD	T211	Y205F	205	Missense	distal	-6	no	12.679	12.616	EPSD	TCGA;ICGC;COSMIC;GDSC;CCLE	7.604	Down-regulation
AGC_PKC_PKCd_PRKCD_ST	P04637	TP53	Q05655	PRKCD	T211	Y205D	205	Missense	distal	-6	no	12.679	12.565	EPSD	TCGA;ICGC;COSMIC	7.604	Down-regulation
AGC_PKC_PKCd_PRKCD_ST	P04637	TP53	Q05655	PRKCD	T211	S215R	215	Missense	distal	4	no	12.679	13.148	EPSD	TCGA;ICGC;COSMIC;GDSC;CCLE	7.604	Up-regulation
AGC_PKC_PKCd_PRKCD_ST	P04637	TP53	Q05655	PRKCD	T211	R209I	209	Missense	proximal	-2	no	12.679	5.954	EPSD	TCGA;ICGC;COSMIC	7.604	Loss
AGC_PKC_PKCd_PRKCD_ST	P04637	TP53	Q05655	PRKCD	T211	T211A	211	Missense	central	0	yes	12.679	0.000	EPSD	TCGA;ICGC;COSMIC;CCLE	7.604	Loss
AGC_PKC_PKCd_PRKCD_ST	P04637	TP53	Q05655	PRKCD	T211	E204D	204	Missense	distal	-7	no	12.679	12.680	EPSD	TCGA;ICGC;COSMIC	7.604	Up-regulation
AGC_PKC_PKCd_PRKCD_ST	P04637	TP53	Q05655	PRKCD	S215	Y220C	220	Missense	distal	5	no	7.714	7.717	EPSD	TCGA;ICGC;COSMIC;GDSC;CCLE	7.604	Up-regulation
AGC_PKC_PKCd_PRKCD_ST	P04637	TP53	Q05655	PRKCD	S215	R213Q	213	Missense	proximal	-2	no	7.714	2.280	EPSD	TCGA;ICGC;COSMIC;GDSC;CCLE	7.604	Loss
AGC_PKC_PKCd_PRKCD_ST	P04637	TP53	Q05655	PRKCD	S215	D208N	208	Missense	distal	-7	no	7.714	7.711	EPSD	TCGA;ICGC;COSMIC	7.604	Down-regulation
AGC_PKC_PKCd_PRKCD_ST	P04637	TP53	Q05655	PRKCD	S215	H214R	214	Missense	proximal	-1	no	7.714	7.859	EPSD	TCGA;ICGC;COSMIC;GDSC;CCLE	7.604	Up-regulation
AGC_PKC_PKCd_PRKCD_ST	P04637	TP53	Q05655	PRKCD	S215	V218E	218	Missense	distal	3	no	7.714	7.695	EPSD	TCGA;ICGC;COSMIC	7.604	Down-regulation
AGC_PKC_PKCd_PRKCD_ST	P04637	TP53	Q05655	PRKCD	S215	Y220H	220	Missense	distal	5	no	7.714	7.929	EPSD	TCGA;ICGC;COSMIC	7.604	Up-regulation
AGC_PKC_PKCd_PRKCD_ST	P04637	TP53	Q05655	PRKCD	S215	S215I	215	Missense	central	0	yes	7.714	0.000	EPSD	TCGA;ICGC;COSMIC;GDSC;CCLE	7.604	Loss
AGC_PKC_PKCd_PRKCD_ST	P04637	TP53	Q05655	PRKCD	S215	V216M	216	Missense	proximal	1	no	7.714	7.717	EPSD	TCGA;ICGC;COSMIC;GDSC;CCLE	7.604	Up-regulation
AGC_PKC_PKCd_PRKCD_ST	P04637	TP53	Q05655	PRKCD	S215	Y220S	220	Missense	distal	5	no	7.714	8.053	EPSD	TCGA;ICGC;COSMIC	7.604	Up-regulation
AGC_PKC_PKCd_PRKCD_ST	P04637	TP53	Q05655	PRKCD	S215	S215N	215	Missense	central	0	yes	7.714	0.000	EPSD	TCGA;ICGC;COSMIC;GDSC;CCLE	7.604	Loss
AGC_PKC_PKCd_PRKCD_ST	P04637	TP53	Q05655	PRKCD	S215	T211I	211	Missense	distal	-4	no	7.714	7.873	EPSD	TCGA;ICGC;COSMIC;CCLE	7.604	Up-regulation
AGC_PKC_PKCd_PRKCD_ST	P04637	TP53	Q05655	PRKCD	S215	V216G	216	Missense	proximal	1	no	7.714	7.704	EPSD	TCGA;ICGC;COSMIC	7.604	Down-regulation
AGC_PKC_PKCd_PRKCD_ST	P04637	TP53	Q05655	PRKCD	S215	R213L	213	Missense	proximal	-2	no	7.714	1.582	EPSD	TCGA;ICGC;COSMIC;GDSC;CCLE	7.604	Loss
AGC_PKC_PKCd_PRKCD_ST	P04637	TP53	Q05655	PRKCD	S215	Y220D	220	Missense	distal	5	no	7.714	7.889	EPSD	TCGA;ICGC;COSMIC;GDSC;CCLE	7.604	Up-regulation
AGC_PKC_PKCd_PRKCD_ST	P04637	TP53	Q05655	PRKCD	S215	V216E	216	Missense	proximal	1	no	7.714	7.761	EPSD	TCGA;ICGC;COSMIC	7.604	Up-regulation
AGC_PKC_PKCd_PRKCD_ST	P04637	TP53	Q05655	PRKCD	S215	R209K	209	Missense	distal	-6	no	7.714	7.665	EPSD	TCGA;COSMIC	7.604	Down-regulation
AGC_PKC_PKCd_PRKCD_ST	P04637	TP53	Q05655	PRKCD	S215	V218G	218	Missense	distal	3	no	7.714	7.733	EPSD	TCGA;ICGC;COSMIC	7.604	Up-regulation
AGC_PKC_PKCd_PRKCD_ST	P04637	TP53	Q05655	PRKCD	S215	R213P	213	Missense	proximal	-2	no	7.714	3.251	EPSD	TCGA;ICGC;COSMIC	7.604	Loss
AGC_PKC_PKCd_PRKCD_ST	P04637	TP53	Q05655	PRKCD	S215	H214L	214	Missense	proximal	-1	no	7.714	7.668	EPSD	TCGA;ICGC;COSMIC	7.604	Down-regulation
AGC_PKC_PKCd_PRKCD_ST	P04637	TP53	Q05655	PRKCD	S215	V216L	216	Missense	proximal	1	no	7.714	7.756	EPSD	TCGA;ICGC;COSMIC;GDSC;CCLE	7.604	Up-regulation
AGC_PKC_PKCd_PRKCD_ST	P04637	TP53	Q05655	PRKCD	S215	D208G	208	Missense	distal	-7	no	7.714	7.712	EPSD	TCGA;ICGC;COSMIC	7.604	Down-regulation
AGC_PKC_PKCd_PRKCD_ST	P04637	TP53	Q05655	PRKCD	S215	S215G	215	Missense	central	0	yes	7.714	0.000	EPSD	TCGA;ICGC;COSMIC;GDSC;CCLE	7.604	Loss
AGC_PKC_PKCd_PRKCD_ST	P04637	TP53	Q05655	PRKCD	S215	R209S	209	Missense	distal	-6	no	7.714	7.915	EPSD	TCGA;ICGC;COSMIC	7.604	Up-regulation
AGC_PKC_PKCd_PRKCD_ST	P04637	TP53	Q05655	PRKCD	S215	R213G	213	Missense	proximal	-2	no	7.714	1.951	EPSD	TCGA;ICGC;COSMIC	7.604	Loss
AGC_PKC_PKCd_PRKCD_ST	P04637	TP53	Q05655	PRKCD	S215	S215R	215	Missense	central	0	yes	7.714	0.000	EPSD	TCGA;ICGC;COSMIC;GDSC;CCLE	7.604	Loss
AGC_PKC_PKCd_PRKCD_ST	P04637	TP53	Q05655	PRKCD	S215	R209I	209	Missense	distal	-6	no	7.714	8.184	EPSD	TCGA;ICGC;COSMIC	7.604	Up-regulation
AGC_PKC_PKCd_PRKCD_ST	P04637	TP53	Q05655	PRKCD	S215	T211A	211	Missense	distal	-4	no	7.714	7.745	EPSD	TCGA;ICGC;COSMIC;CCLE	7.604	Up-regulation
AGC_PKC_PKCd_PRKCD_ST	P04637	TP53	Q05655	PRKCD	S269	R273C	273	Missense	distal	4	no	8.933	8.137	EPSD	TCGA;ICGC;COSMIC;GDSC;CCLE	7.604	Down-regulation
AGC_PKC_PKCd_PRKCD_ST	P04637	TP53	Q05655	PRKCD	S269	C275S	275	Missense	distal	6	no	8.933	8.975	EPSD	TCGA;ICGC;COSMIC	7.604	Up-regulation
AGC_PKC_PKCd_PRKCD_ST	P04637	TP53	Q05655	PRKCD	S269	R273L	273	Missense	distal	4	no	8.933	8.297	EPSD	TCGA;ICGC;COSMIC;GDSC;CCLE	7.604	Down-regulation
AGC_PKC_PKCd_PRKCD_ST	P04637	TP53	Q05655	PRKCD	S269	E271K	271	Missense	proximal	2	no	8.933	14.688	EPSD	TCGA;ICGC;COSMIC;GDSC;CCLE	7.604	Up-regulation
AGC_PKC_PKCd_PRKCD_ST	P04637	TP53	Q05655	PRKCD	S269	C275Y	275	Missense	distal	6	no	8.933	8.935	EPSD	TCGA;ICGC;COSMIC;GDSC;CCLE	7.604	Up-regulation
AGC_PKC_PKCd_PRKCD_ST	P04637	TP53	Q05655	PRKCD	S269	R273S	273	Missense	distal	4	no	8.933	8.463	EPSD	TCGA;ICGC;COSMIC	7.604	Down-regulation
AGC_PKC_PKCd_PRKCD_ST	P04637	TP53	Q05655	PRKCD	S269	E271Q	271	Missense	proximal	2	no	8.933	9.076	EPSD	TCGA;ICGC;COSMIC	7.604	Up-regulation
AGC_PKC_PKCd_PRKCD_ST	P04637	TP53	Q05655	PRKCD	S269	L265P	265	Missense	distal	-4	no	8.933	8.794	EPSD	TCGA;ICGC;COSMIC;GDSC;CCLE	7.604	Down-regulation
AGC_PKC_PKCd_PRKCD_ST	P04637	TP53	Q05655	PRKCD	S269	V272M	272	Missense	distal	3	no	8.933	8.959	EPSD	TCGA;ICGC;COSMIC;GDSC;CCLE	7.604	Up-regulation
AGC_PKC_PKCd_PRKCD_ST	P04637	TP53	Q05655	PRKCD	S269	G266E	266	Missense	distal	-3	no	8.933	8.721	EPSD	TCGA;ICGC;COSMIC;GDSC;CCLE	7.604	Down-regulation
AGC_PKC_PKCd_PRKCD_ST	P04637	TP53	Q05655	PRKCD	S269	R273P	273	Missense	distal	4	no	8.933	8.501	EPSD	TCGA;ICGC;COSMIC	7.604	Down-regulation
AGC_PKC_PKCd_PRKCD_ST	P04637	TP53	Q05655	PRKCD	S269	F270I	270	Missense	proximal	1	no	8.933	8.878	EPSD	TCGA;ICGC;COSMIC	7.604	Down-regulation
AGC_PKC_PKCd_PRKCD_ST	P04637	TP53	Q05655	PRKCD	S269	R273H	273	Missense	distal	4	no	8.933	8.390	EPSD	TCGA;ICGC;COSMIC;GDSC;CCLE	7.604	Down-regulation
AGC_PKC_PKCd_PRKCD_ST	P04637	TP53	Q05655	PRKCD	S269	A276P	276	Missense	distal	7	no	8.933	8.930	EPSD	TCGA;ICGC;COSMIC	7.604	Down-regulation
AGC_PKC_PKCd_PRKCD_ST	P04637	TP53	Q05655	PRKCD	S269	V272L	272	Missense	distal	3	no	8.933	8.944	EPSD	TCGA;ICGC;COSMIC;GDSC;CCLE	7.604	Up-regulation
AGC_PKC_PKCd_PRKCD_ST	P04637	TP53	Q05655	PRKCD	S269	V274D	274	Missense	distal	5	no	8.933	9.025	EPSD	TCGA;ICGC;COSMIC;CCLE	7.604	Up-regulation
AGC_PKC_PKCd_PRKCD_ST	P04637	TP53	Q05655	PRKCD	S269	G266V	266	Missense	distal	-3	no	8.933	9.341	EPSD	TCGA;ICGC;COSMIC;GDSC;CCLE	7.604	Up-regulation
AGC_PKC_PKCd_PRKCD_ST	P04637	TP53	Q05655	PRKCD	S269	R267L	267	Missense	proximal	-2	no	8.933	2.800	EPSD	TCGA;ICGC;COSMIC;GDSC;CCLE	7.604	Loss
AGC_PKC_PKCd_PRKCD_ST	P04637	TP53	Q05655	PRKCD	S269	R267W	267	Missense	proximal	-2	no	8.933	2.679	EPSD	TCGA;ICGC;COSMIC;GDSC;CCLE	7.604	Loss
AGC_PKC_PKCd_PRKCD_ST	P04637	TP53	Q05655	PRKCD	S269	R267Q	267	Missense	proximal	-2	no	8.933	3.498	EPSD	TCGA;ICGC;COSMIC;CCLE	7.604	Loss
AGC_PKC_PKCd_PRKCD_ST	P04637	TP53	Q05655	PRKCD	S269	C275F	275	Missense	distal	6	no	8.933	8.949	EPSD	TCGA;ICGC;COSMIC;GDSC;CCLE	7.604	Up-regulation
AGC_PKC_PKCd_PRKCD_ST	P04637	TP53	Q05655	PRKCD	S269	V274G	274	Missense	distal	5	no	8.933	8.975	EPSD	TCGA;ICGC;COSMIC;CCLE	7.604	Up-regulation
AGC_PKC_PKCd_PRKCD_ST	P04637	TP53	Q05655	PRKCD	S269	V274L	274	Missense	distal	5	no	8.933	9.000	EPSD	TCGA;ICGC;COSMIC	7.604	Up-regulation
AGC_PKC_PKCd_PRKCD_ST	P04637	TP53	Q05655	PRKCD	S269	G266R	266	Missense	distal	-3	no	8.933	14.142	EPSD	TCGA;ICGC;COSMIC;GDSC;CCLE	7.604	Up-regulation
AGC_PKC_PKCd_PRKCD_ST	P04637	TP53	Q05655	PRKCD	S269	R267P	267	Missense	proximal	-2	no	8.933	4.470	EPSD	TCGA;ICGC;COSMIC;GDSC;CCLE	7.604	Loss
AGC_PKC_PKCd_PRKCD_ST	P04637	TP53	Q05655	PRKCD	S269	A276D	276	Missense	distal	7	no	8.933	8.917	EPSD	TCGA;ICGC;COSMIC	7.604	Down-regulation
AGC_PKC_PKCd_PRKCD_ST	P04637	TP53	Q05655	PRKCD	S269	L265R	265	Missense	distal	-4	no	8.933	8.540	EPSD	TCGA;ICGC;COSMIC	7.604	Down-regulation
AGC_PKC_PKCd_PRKCD_ST	P04637	TP53	Q05655	PRKCD	S269	R267G	267	Missense	proximal	-2	no	8.933	3.169	EPSD	TCGA;ICGC;COSMIC	7.604	Loss
AGC_PKC_PKCd_PRKCD_ST	P04637	TP53	Q05655	PRKCD	S269	F270C	270	Missense	proximal	1	no	8.933	8.864	EPSD	TCGA;ICGC;COSMIC	7.604	Down-regulation
AGC_PKC_PKCd_PRKCD_ST	P04637	TP53	Q05655	PRKCD	S269	E271V	271	Missense	proximal	2	no	8.933	9.495	EPSD	TCGA;ICGC;COSMIC	7.604	Up-regulation
AGC_PKC_PKCd_PRKCD_ST	P04637	TP53	Q05655	PRKCD	S269	G262V	262	Missense	distal	-7	no	8.933	8.931	EPSD	TCGA;ICGC;COSMIC;GDSC;CCLE	7.604	Down-regulation
AGC_PKC_PKCd_PRKCD_ST	P04637	TP53	Q05655	PRKCD	S269	V274F	274	Missense	distal	5	no	8.933	8.979	EPSD	TCGA;ICGC;COSMIC;GDSC;CCLE	7.604	Up-regulation
AGC_PKC_PKCd_PRKCD_ST	P04637	TP53	Q05655	PRKCD	S269	F270S	270	Missense	proximal	1	no	8.933	8.982	EPSD	TCGA;ICGC;COSMIC	7.604	Up-regulation
AGC_PKC_PKCd_PRKCD_ST	P04637	TP53	Q05655	PRKCD	S269	C275R	275	Missense	distal	6	no	8.933	9.008	EPSD	TCGA;ICGC;COSMIC	7.604	Up-regulation
AGC_PKC_PKCd_PRKCD_ST	P04637	TP53	Q05655	PRKCD	S269	C275G	275	Missense	distal	6	no	8.933	8.949	EPSD	TCGA;ICGC;COSMIC;GDSC;CCLE	7.604	Up-regulation
AGC_PKC_PKCd_PRKCD_ST	P04637	TP53	Q05655	PRKCD	S269	A276G	276	Missense	distal	7	no	8.933	8.914	EPSD	TCGA;ICGC;COSMIC	7.604	Down-regulation
AGC_PKC_PKCd_PRKCD_ST	P04637	TP53	Q05655	PRKCD	S269	V272G	272	Missense	distal	3	no	8.933	8.951	EPSD	TCGA;ICGC;COSMIC	7.604	Up-regulation
AGC_PKC_PKCd_PRKCD_ST	P04637	TP53	Q05655	PRKCD	S269	R273G	273	Missense	distal	4	no	8.933	8.265	EPSD	TCGA;ICGC;COSMIC	7.604	Down-regulation
AGC_PKC_PKCd_PRKCD_ST	P04637	TP53	Q05655	PRKCD	S269	F270V	270	Missense	proximal	1	no	8.933	8.886	EPSD	TCGA;ICGC;COSMIC	7.604	Down-regulation
AGC_PKC_PKCd_PRKCD_ST	P04637	TP53	Q05655	PRKCD	S269	C275W	275	Missense	distal	6	no	8.933	8.917	EPSD	TCGA;ICGC;COSMIC	7.604	Down-regulation
AGC_PKC_PKCd_PRKCD_ST	P04637	TP53	Q05655	PRKCD	S269	V272A	272	Missense	distal	3	no	8.933	9.165	EPSD	TCGA;ICGC;COSMIC	7.604	Up-regulation
AGC_PKC_PKCd_PRKCD_ST	P04637	TP53	Q05655	PRKCD	S269	F270L	270	Missense	proximal	1	no	8.933	8.927	EPSD	TCGA;ICGC;COSMIC	7.604	Down-regulation
AGC_PKC_PKCd_PRKCD_ST	P04637	TP53	Q05655	PRKCD	T284	E286K	286	Missense	proximal	2	no	4.033	9.788	EPSD	TCGA;ICGC;COSMIC;GDSC;CCLE	7.604	Gain
AGC_PKC_PKCd_PRKCD_ST	P04637	TP53	Q05655	PRKCD	S371	S376C	376	Missense	distal	5	no	9.551	9.215	EPSD	TCGA;ICGC;COSMIC	7.604	Down-regulation
AGC_PKC_PKCd_PRKCD_ST	P04637	TP53	Q05655	PRKCD	S371	Q375K	375	Missense	distal	4	no	9.551	10.131	EPSD	TCGA;ICGC;COSMIC	7.604	Up-regulation
AGC_PKC_PKCd_PRKCD_ST	P04637	TP53	Q05655	PRKCD	S376	S376C	376	Missense	central	0	yes	8.153	0.000	EPSD	TCGA;ICGC;COSMIC	7.604	Loss
AGC_PKC_PKCd_PRKCD_ST	P04637	TP53	Q05655	PRKCD	S376	Q375K	375	Missense	proximal	-1	no	8.153	8.283	EPSD	TCGA;ICGC;COSMIC	7.604	Up-regulation
AGC_PKC_PKCd_PRKCD_ST	P04637	TP53	Q05655	PRKCD	T377	S376C	376	Missense	proximal	-1	no	8.421	8.285	EPSD	TCGA;ICGC;COSMIC	7.604	Down-regulation
AGC_PKC_PKCd_PRKCD_ST	P04637	TP53	Q05655	PRKCD	T377	Q375K	375	Missense	proximal	-2	no	8.421	12.610	EPSD	TCGA;ICGC;COSMIC	7.604	Up-regulation
AGC_PKC_PKCd_PRKCD_ST	P04637	TP53	Q05655	PRKCD	S378	Q375K	375	Missense	distal	-3	no	5.512	9.634	EPSD	TCGA;ICGC;COSMIC	7.604	Gain
AGC_PKC_PKCd_PRKCD_ST	P06401	PGR	Q05655	PRKCD	S190	L197F	197	Missense	distal	7	no	9.830	9.841	EPSD	TCGA;ICGC;COSMIC	7.604	Up-regulation
AGC_PKC_PKCd_PRKCD_ST	P06401	PGR	Q05655	PRKCD	S276	S276L	276	Missense	central	0	yes	10.275	0.000	EPSD	TCGA;ICGC;COSMIC;CCLE	7.604	Loss
AGC_PKC_PKCd_PRKCD_ST	P06401	PGR	Q05655	PRKCD	S276	R274H	274	Missense	proximal	-2	no	10.275	5.300	EPSD	TCGA;ICGC;COSMIC	7.604	Loss
AGC_PKC_PKCd_PRKCD_ST	P06401	PGR	Q05655	PRKCD	S397	A394V	394	Missense	distal	-3	no	8.825	8.363	EPSD	TCGA;ICGC	7.604	Down-regulation
AGC_PKC_PKCd_PRKCD_ST	P06401	PGR	Q05655	PRKCD	S400	A394V	394	Missense	distal	-6	no	10.978	11.103	PhosphoSitePlus	TCGA;ICGC	7.604	Up-regulation
AGC_PKC_PKCd_PRKCD_ST	P06401	PGR	Q05655	PRKCD	S549	Q556H	556	Missense	distal	7	no	9.693	9.698	EPSD	TCGA;ICGC	7.604	Up-regulation
AGC_PKC_PKCd_PRKCD_ST	P06401	PGR	Q05655	PRKCD	S549	S552N	552	Missense	distal	3	no	9.693	9.422	EPSD	TCGA;ICGC;COSMIC	7.604	Down-regulation
AGC_PKC_PKCd_PRKCD_ST	Q8TCU6	PREX1	Q05655	PRKCD	S43	A39T	39	Missense	distal	-4	no	15.026	14.996	EPSD	TCGA;ICGC;COSMIC	7.604	Down-regulation
AGC_PKC_PKCd_PRKCD_ST	Q8TCU6	PREX1	Q05655	PRKCD	T308	R303Q	303	Missense	distal	-5	no	8.800	8.449	EPSD	TCGA;ICGC;COSMIC	7.604	Down-regulation
AGC_PKC_PKCd_PRKCD_ST	Q8TCU6	PREX1	Q05655	PRKCD	S310	R303Q	303	Missense	distal	-7	no	7.760	7.743	EPSD	TCGA;ICGC;COSMIC	7.604	Down-regulation
AGC_PKC_PKCd_PRKCD_ST	Q8TCU6	PREX1	Q05655	PRKCD	S313	I320M	320	Missense	distal	7	no	13.449	13.460	PhosphoSitePlus	TCGA;ICGC;COSMIC	7.604	Up-regulation
AGC_PKC_PKCd_PRKCD_ST	Q8TCU6	PREX1	Q05655	PRKCD	T314	I320M	320	Missense	distal	6	no	15.960	15.966	EPSD	TCGA;ICGC;COSMIC	7.604	Up-regulation
AGC_PKC_PKCd_PRKCD_ST	Q8TCU6	PREX1	Q05655	PRKCD	S436	V438A	438	Missense	proximal	2	no	12.642	13.790	EPSD	TCGA;ICGC;COSMIC	7.604	Up-regulation
AGC_PKC_PKCd_PRKCD_ST	Q8TCU6	PREX1	Q05655	PRKCD	S436	R431H	431	Missense	distal	-5	no	12.642	12.306	EPSD	TCGA;ICGC;COSMIC;CCLE	7.604	Down-regulation
AGC_PKC_PKCd_PRKCD_ST	Q8TCU6	PREX1	Q05655	PRKCD	S436	P439S	439	Missense	distal	3	no	12.642	12.649	EPSD	TCGA;ICGC;COSMIC	7.604	Up-regulation
AGC_PKC_PKCd_PRKCD_ST	Q8TCU6	PREX1	Q05655	PRKCD	S436	R432Q	432	Missense	distal	-4	no	12.642	12.958	EPSD	TCGA;ICGC;COSMIC	7.604	Up-regulation
AGC_PKC_PKCd_PRKCD_ST	Q8TCU6	PREX1	Q05655	PRKCD	S682	N689K	689	Missense	distal	7	no	7.483	7.624	EPSD	TCGA;ICGC;COSMIC	7.604	Gain
AGC_PKC_PKCd_PRKCD_ST	Q8TCU6	PREX1	Q05655	PRKCD	S694	L698Q	698	Missense	distal	4	no	9.491	9.539	EPSD	TCGA;ICGC;COSMIC	7.604	Up-regulation
AGC_PKC_PKCd_PRKCD_ST	Q8TCU6	PREX1	Q05655	PRKCD	S694	N689K	689	Missense	distal	-5	no	9.491	9.870	EPSD	TCGA;ICGC;COSMIC	7.604	Up-regulation
AGC_PKC_PKCd_PRKCD_ST	Q8TCU6	PREX1	Q05655	PRKCD	S694	R695H	695	Missense	proximal	1	no	9.491	9.356	EPSD	TCGA;ICGC;COSMIC	7.604	Down-regulation
AGC_PKC_PKCd_PRKCD_ST	Q8TCU6	PREX1	Q05655	PRKCD	S694	P697L	697	Missense	distal	3	no	9.491	9.210	EPSD	TCGA;ICGC;COSMIC;CCLE	7.604	Down-regulation
AGC_PKC_PKCd_PRKCD_ST	Q8TCU6	PREX1	Q05655	PRKCD	S694	P697S	697	Missense	distal	3	no	9.491	9.497	EPSD	TCGA;ICGC;COSMIC	7.604	Up-regulation
AGC_PKC_PKCd_PRKCD_ST	Q8TCU6	PREX1	Q05655	PRKCD	S694	R699C	699	Missense	distal	5	no	9.491	8.926	EPSD	TCGA;ICGC;COSMIC	7.604	Down-regulation
AGC_PKC_PKCd_PRKCD_ST	Q8TCU6	PREX1	Q05655	PRKCD	S993	R995C	995	Missense	proximal	2	no	14.544	7.665	EPSD	TCGA;ICGC;COSMIC	7.604	Down-regulation
AGC_PKC_PKCd_PRKCD_ST	Q8TCU6	PREX1	Q05655	PRKCD	S993	R998C	998	Missense	distal	5	no	14.544	13.979	EPSD	TCGA;ICGC;COSMIC	7.604	Down-regulation
AGC_PKC_PKCd_PRKCD_ST	Q8TCU6	PREX1	Q05655	PRKCD	S1001	G1004S	1004	Missense	distal	3	no	11.614	11.894	EPSD	TCGA;ICGC;COSMIC;CCLE	7.604	Up-regulation
AGC_PKC_PKCd_PRKCD_ST	Q8TCU6	PREX1	Q05655	PRKCD	S1001	R995C	995	Missense	distal	-6	no	11.614	12.084	EPSD	TCGA;ICGC;COSMIC	7.604	Up-regulation
AGC_PKC_PKCd_PRKCD_ST	Q8TCU6	PREX1	Q05655	PRKCD	S1001	D1006H	1006	Missense	distal	5	no	11.614	11.655	EPSD	TCGA	7.604	Up-regulation
AGC_PKC_PKCd_PRKCD_ST	Q8TCU6	PREX1	Q05655	PRKCD	S1001	P1007L	1007	Missense	distal	6	no	11.614	11.590	EPSD	TCGA;ICGC;COSMIC	7.604	Down-regulation
AGC_PKC_PKCd_PRKCD_ST	Q8TCU6	PREX1	Q05655	PRKCD	S1001	R998C	998	Missense	distal	-3	no	11.614	6.295	EPSD	TCGA;ICGC;COSMIC	7.604	Loss
AGC_PKC_PKCd_PRKCD_ST	P78536	ADAM17	Q05655	PRKCD	T87	T84P	84	Missense	distal	-3	no	7.297	8.146	EPSD	TCGA;ICGC;COSMIC	7.604	Gain
AGC_PKC_PKCd_PRKCD_ST	P78536	ADAM17	Q05655	PRKCD	S180	P181L	181	Missense	proximal	1	no	12.249	12.174	EPSD	TCGA;ICGC;COSMIC	7.604	Down-regulation
AGC_PKC_PKCd_PRKCD_ST	P78536	ADAM17	Q05655	PRKCD	S180	S176L	176	Missense	distal	-4	no	12.249	12.409	EPSD	TCGA;ICGC;COSMIC	7.604	Up-regulation
AGC_PKC_PKCd_PRKCD_ST	P78536	ADAM17	Q05655	PRKCD	S180	R177C	177	Missense	distal	-3	no	12.249	6.929	EPSD	TCGA;ICGC;COSMIC	7.604	Loss
AGC_PKC_PKCd_PRKCD_ST	P78536	ADAM17	Q05655	PRKCD	S723	R725H	725	Missense	proximal	2	no	9.514	3.954	EPSD	TCGA;ICGC;COSMIC	7.604	Loss
AGC_PKC_PKCd_PRKCD_ST	P78536	ADAM17	Q05655	PRKCD	S723	M719I	719	Missense	distal	-4	no	9.514	9.564	EPSD	TCGA;ICGC;COSMIC	7.604	Up-regulation
AGC_PKC_PKCd_PRKCD_ST	P78536	ADAM17	Q05655	PRKCD	S723	S723L	723	Missense	central	0	yes	9.514	0.000	EPSD	TCGA;ICGC;COSMIC	7.604	Loss
AGC_PKC_PKCd_PRKCD_ST	P78536	ADAM17	Q05655	PRKCD	S808	R813C	813	Missense	distal	5	no	12.777	12.212	EPSD	TCGA;ICGC;COSMIC	7.604	Down-regulation
AGC_PKC_PKCd_PRKCD_ST	P78536	ADAM17	Q05655	PRKCD	S808	R802K	802	Missense	distal	-6	no	12.777	12.727	EPSD	TCGA;ICGC;COSMIC	7.604	Down-regulation
AGC_PKC_PKCd_PRKCD_ST	P78536	ADAM17	Q05655	PRKCD	S808	A806V	806	Missense	proximal	-2	no	12.777	12.146	EPSD	TCGA;ICGC;COSMIC	7.604	Down-regulation
AGC_PKC_PKCd_PRKCD_ST	P12830	CDH1	Q05655	PRKCD	S853	S850F	850	Missense	distal	-3	no	8.160	8.212	EPSD	TCGA;COSMIC	7.604	Up-regulation
AGC_PKC_PKCd_PRKCD_ST	P21730	C5AR1	Q05655	PRKCD	S314	G309D	309	Missense	distal	-5	no	8.341	8.372	EPSD	TCGA;ICGC;COSMIC	7.604	Up-regulation
AGC_PKC_PKCd_PRKCD_ST	P21730	C5AR1	Q05655	PRKCD	S314	S314F	314	Missense	central	0	yes	8.341	0.000	EPSD	TCGA;ICGC;COSMIC	7.604	Loss
AGC_PKC_PKCd_PRKCD_ST	P21730	C5AR1	Q05655	PRKCD	S314	P316S	316	Missense	proximal	2	no	8.341	8.096	EPSD	TCGA;ICGC;COSMIC;GDSC;CCLE	7.604	Down-regulation
AGC_PKC_PKCd_PRKCD_ST	P21730	C5AR1	Q05655	PRKCD	S314	R320Q	320	Missense	distal	6	no	8.341	8.294	EPSD	TCGA;ICGC;COSMIC	7.604	Down-regulation
AGC_PKC_PKCd_PRKCD_ST	P21730	C5AR1	Q05655	PRKCD	S314	L315I	315	Missense	proximal	1	no	8.341	8.292	EPSD	TCGA;ICGC;COSMIC	7.604	Down-regulation
AGC_PKC_PKCd_PRKCD_ST	P21730	C5AR1	Q05655	PRKCD	S332	S338Y	338	Missense	distal	6	no	9.823	9.783	EPSD	TCGA;ICGC;COSMIC	7.604	Down-regulation
AGC_PKC_PKCd_PRKCD_ST	P35568	IRS1	Q05655	PRKCD	S24	R20C	20	Missense	distal	-4	no	11.075	11.510	EPSD	TCGA;ICGC;COSMIC	7.604	Up-regulation
AGC_PKC_PKCd_PRKCD_ST	P35568	IRS1	Q05655	PRKCD	S24	R20H	20	Missense	distal	-4	no	11.075	11.367	EPSD	TCGA;ICGC	7.604	Up-regulation
AGC_PKC_PKCd_PRKCD_ST	P35568	IRS1	Q05655	PRKCD	S36	E37K	37	Missense	proximal	1	no	7.588	7.749	EPSD	TCGA;ICGC;COSMIC;GDSC;CCLE	7.604	Gain
AGC_PKC_PKCd_PRKCD_ST	P35568	IRS1	Q05655	PRKCD	S268	E263K	263	Missense	distal	-5	no	8.493	8.850	EPSD	TCGA;ICGC;COSMIC	7.604	Up-regulation
AGC_PKC_PKCd_PRKCD_ST	P35568	IRS1	Q05655	PRKCD	S268	K269N	269	Missense	proximal	1	no	8.493	8.297	EPSD	TCGA;ICGC;COSMIC	7.604	Down-regulation
AGC_PKC_PKCd_PRKCD_ST	P35568	IRS1	Q05655	PRKCD	S268	P266S	266	Missense	proximal	-2	no	8.493	8.107	EPSD	TCGA;ICGC;COSMIC	7.604	Down-regulation
AGC_PKC_PKCd_PRKCD_ST	P35568	IRS1	Q05655	PRKCD	S268	S261I	261	Missense	distal	-7	no	8.493	8.478	EPSD	TCGA;ICGC;COSMIC	7.604	Down-regulation
AGC_PKC_PKCd_PRKCD_ST	P35568	IRS1	Q05655	PRKCD	S268	N275S	275	Missense	distal	7	no	8.493	8.542	EPSD	TCGA;ICGC;COSMIC	7.604	Up-regulation
AGC_PKC_PKCd_PRKCD_ST	P35568	IRS1	Q05655	PRKCD	S270	E263K	263	Missense	distal	-7	no	9.706	9.729	EPSD	TCGA;ICGC;COSMIC	7.604	Up-regulation
AGC_PKC_PKCd_PRKCD_ST	P35568	IRS1	Q05655	PRKCD	S270	K269N	269	Missense	proximal	-1	no	9.706	9.525	EPSD	TCGA;ICGC;COSMIC	7.604	Down-regulation
AGC_PKC_PKCd_PRKCD_ST	P35568	IRS1	Q05655	PRKCD	S270	P266S	266	Missense	distal	-4	no	9.706	9.685	EPSD	TCGA;ICGC;COSMIC	7.604	Down-regulation
AGC_PKC_PKCd_PRKCD_ST	P35568	IRS1	Q05655	PRKCD	S270	C276F	276	Missense	distal	6	no	9.706	9.722	EPSD	TCGA;ICGC;COSMIC	7.604	Up-regulation
AGC_PKC_PKCd_PRKCD_ST	P35568	IRS1	Q05655	PRKCD	S270	N275S	275	Missense	distal	5	no	9.706	9.924	EPSD	TCGA;ICGC;COSMIC	7.604	Up-regulation
AGC_PKC_PKCd_PRKCD_ST	P35568	IRS1	Q05655	PRKCD	S272	C276F	276	Missense	distal	4	no	7.493	7.675	EPSD	TCGA;ICGC;COSMIC	7.604	Gain
AGC_PKC_PKCd_PRKCD_ST	P35568	IRS1	Q05655	PRKCD	S272	N275S	275	Missense	distal	3	no	7.493	7.765	EPSD	TCGA;ICGC;COSMIC	7.604	Gain
AGC_PKC_PKCd_PRKCD_ST	P35568	IRS1	Q05655	PRKCD	S307	A314G	314	Missense	distal	7	no	8.043	8.024	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	7.604	Down-regulation
AGC_PKC_PKCd_PRKCD_ST	P35568	IRS1	Q05655	PRKCD	S323	R327H	327	Missense	distal	4	no	13.662	13.119	EPSD;PhosphoSitePlus	TCGA;ICGC	7.604	Down-regulation
AGC_PKC_PKCd_PRKCD_ST	P35568	IRS1	Q05655	PRKCD	S323	A328T	328	Missense	distal	5	no	13.662	13.702	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	7.604	Up-regulation
AGC_PKC_PKCd_PRKCD_ST	P35568	IRS1	Q05655	PRKCD	S323	S330N	330	Missense	distal	7	no	13.662	13.613	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	7.604	Down-regulation
AGC_PKC_PKCd_PRKCD_ST	P35568	IRS1	Q05655	PRKCD	S323	S323A	323	Missense	central	0	yes	13.662	0.000	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	7.604	Loss
AGC_PKC_PKCd_PRKCD_ST	P35568	IRS1	Q05655	PRKCD	S323	P321L	321	Missense	proximal	-2	no	13.662	11.992	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	7.604	Down-regulation
AGC_PKC_PKCd_PRKCD_ST	P35568	IRS1	Q05655	PRKCD	S341	T335I	335	Missense	distal	-6	no	7.893	8.122	EPSD	TCGA;ICGC;COSMIC	7.604	Up-regulation
AGC_PKC_PKCd_PRKCD_ST	P35568	IRS1	Q05655	PRKCD	S341	R338H	338	Missense	distal	-3	no	7.893	3.639	EPSD	TCGA;ICGC;COSMIC	7.604	Loss
AGC_PKC_PKCd_PRKCD_ST	P35568	IRS1	Q05655	PRKCD	S341	R338C	338	Missense	distal	-3	no	7.893	2.574	EPSD	TCGA;ICGC;COSMIC	7.604	Loss
AGC_PKC_PKCd_PRKCD_ST	P35568	IRS1	Q05655	PRKCD	S341	P346H	346	Missense	distal	5	no	7.893	7.738	EPSD	TCGA;ICGC	7.604	Down-regulation
AGC_PKC_PKCd_PRKCD_ST	P35568	IRS1	Q05655	PRKCD	T351	A356T	356	Missense	distal	5	no	7.871	7.910	EPSD	TCGA;ICGC;COSMIC	7.604	Up-regulation
AGC_PKC_PKCd_PRKCD_ST	P35568	IRS1	Q05655	PRKCD	T351	P346H	346	Missense	distal	-5	no	7.871	7.818	EPSD	TCGA;ICGC	7.604	Down-regulation
AGC_PKC_PKCd_PRKCD_ST	P35568	IRS1	Q05655	PRKCD	S362	A363D	363	Missense	proximal	1	no	14.525	14.527	EPSD	TCGA;ICGC;COSMIC	7.604	Up-regulation
AGC_PKC_PKCd_PRKCD_ST	P35568	IRS1	Q05655	PRKCD	S362	A356T	356	Missense	distal	-6	no	14.525	14.448	EPSD	TCGA;ICGC;COSMIC	7.604	Down-regulation
AGC_PKC_PKCd_PRKCD_ST	P35568	IRS1	Q05655	PRKCD	S362	A363T	363	Missense	proximal	1	no	14.525	14.587	EPSD	TCGA;ICGC;COSMIC	7.604	Up-regulation
AGC_PKC_PKCd_PRKCD_ST	P35568	IRS1	Q05655	PRKCD	S362	R360W	360	Missense	proximal	-2	no	14.525	8.271	EPSD	TCGA;ICGC;CCLE	7.604	Down-regulation
AGC_PKC_PKCd_PRKCD_ST	P35568	IRS1	Q05655	PRKCD	S362	H359R	359	Missense	distal	-3	no	14.525	18.780	EPSD	TCGA;ICGC	7.604	Up-regulation
AGC_PKC_PKCd_PRKCD_ST	P35568	IRS1	Q05655	PRKCD	S383	P389L	389	Missense	distal	6	no	7.873	7.849	EPSD	TCGA;ICGC;COSMIC	7.604	Down-regulation
AGC_PKC_PKCd_PRKCD_ST	P35568	IRS1	Q05655	PRKCD	S383	R381H	381	Missense	proximal	-2	no	7.873	2.897	EPSD	TCGA	7.604	Loss
AGC_PKC_PKCd_PRKCD_ST	P35568	IRS1	Q05655	PRKCD	S383	P384H	384	Missense	proximal	1	no	7.873	7.813	EPSD	TCGA;ICGC;COSMIC	7.604	Down-regulation
AGC_PKC_PKCd_PRKCD_ST	P35568	IRS1	Q05655	PRKCD	S383	P378S	378	Missense	distal	-5	no	7.873	7.882	EPSD	TCGA;ICGC;COSMIC	7.604	Up-regulation
AGC_PKC_PKCd_PRKCD_ST	P35568	IRS1	Q05655	PRKCD	S412	R411Q	411	Missense	proximal	-1	no	8.948	8.812	EPSD	TCGA;ICGC	7.604	Down-regulation
AGC_PKC_PKCd_PRKCD_ST	P35568	IRS1	Q05655	PRKCD	S413	R411Q	411	Missense	proximal	-2	no	12.056	6.621	EPSD	TCGA;ICGC	7.604	Loss
AGC_PKC_PKCd_PRKCD_ST	P35568	IRS1	Q05655	PRKCD	S441	F438V	438	Missense	distal	-3	no	14.704	14.426	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	7.604	Down-regulation
AGC_PKC_PKCd_PRKCD_ST	P35568	IRS1	Q05655	PRKCD	S441	V445I	445	Missense	distal	4	no	14.704	14.638	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	7.604	Down-regulation
AGC_PKC_PKCd_PRKCD_ST	P35568	IRS1	Q05655	PRKCD	S441	R443H	443	Missense	proximal	2	no	14.704	9.143	EPSD;PhosphoSitePlus	TCGA;ICGC	7.604	Down-regulation
AGC_PKC_PKCd_PRKCD_ST	P35568	IRS1	Q05655	PRKCD	T525	R520W	520	Missense	distal	-5	no	10.973	10.428	EPSD	TCGA;ICGC;COSMIC	7.604	Down-regulation
AGC_PKC_PKCd_PRKCD_ST	P35568	IRS1	Q05655	PRKCD	T525	R522Q	522	Missense	distal	-3	no	10.973	5.815	EPSD	TCGA;ICGC;COSMIC	7.604	Loss
AGC_PKC_PKCd_PRKCD_ST	P35568	IRS1	Q05655	PRKCD	T525	R520Q	520	Missense	distal	-5	no	10.973	10.622	EPSD	TCGA;ICGC;COSMIC	7.604	Down-regulation
AGC_PKC_PKCd_PRKCD_ST	P35568	IRS1	Q05655	PRKCD	S603	H607R	607	Missense	distal	4	no	8.411	8.954	EPSD	TCGA;ICGC	7.604	Up-regulation
AGC_PKC_PKCd_PRKCD_ST	P35568	IRS1	Q05655	PRKCD	S603	R600C	600	Missense	distal	-3	no	8.411	3.092	EPSD	TCGA;ICGC;COSMIC	7.604	Loss
AGC_PKC_PKCd_PRKCD_ST	P35568	IRS1	Q05655	PRKCD	S792	R797C	797	Missense	distal	5	no	8.515	7.950	EPSD	TCGA;ICGC;COSMIC	7.604	Down-regulation
AGC_PKC_PKCd_PRKCD_ST	P35568	IRS1	Q05655	PRKCD	S795	R797C	797	Missense	proximal	2	no	7.681	0.802	EPSD	TCGA;ICGC;COSMIC	7.604	Loss
AGC_PKC_PKCd_PRKCD_ST	P35568	IRS1	Q05655	PRKCD	S862	A856T	856	Missense	distal	-6	no	8.316	8.239	EPSD	TCGA;ICGC;COSMIC	7.604	Down-regulation
AGC_PKC_PKCd_PRKCD_ST	P35568	IRS1	Q05655	PRKCD	S862	R857W	857	Missense	distal	-5	no	8.316	7.771	EPSD	TCGA;ICGC;COSMIC	7.604	Down-regulation
AGC_PKC_PKCd_PRKCD_ST	P35568	IRS1	Q05655	PRKCD	S869	E876Q	876	Missense	distal	7	no	8.590	8.607	EPSD	TCGA;ICGC;COSMIC	7.604	Up-regulation
AGC_PKC_PKCd_PRKCD_ST	P35568	IRS1	Q05655	PRKCD	T870	E876Q	876	Missense	distal	6	no	7.797	7.803	EPSD	TCGA;ICGC;COSMIC	7.604	Up-regulation
AGC_PKC_PKCd_PRKCD_ST	P35568	IRS1	Q05655	PRKCD	S984	R986W	986	Missense	proximal	2	no	8.916	2.243	EPSD	TCGA;ICGC;COSMIC;GDSC;CCLE	7.604	Loss
AGC_PKC_PKCd_PRKCD_ST	P35568	IRS1	Q05655	PRKCD	S1000	S1005L	1005	Missense	distal	5	no	8.052	7.862	EPSD	TCGA;ICGC	7.604	Down-regulation
AGC_PKC_PKCd_PRKCD_ST	P35568	IRS1	Q05655	PRKCD	S1025	E1023K	1023	Missense	proximal	-2	no	3.703	8.683	EPSD	TCGA;ICGC;COSMIC	7.604	Gain
AGC_PKC_PKCd_PRKCD_ST	P35568	IRS1	Q05655	PRKCD	S1084	R1081H	1081	Missense	distal	-3	no	12.466	8.211	EPSD	TCGA;ICGC;COSMIC	7.604	Down-regulation
AGC_PKC_PKCd_PRKCD_ST	P35568	IRS1	Q05655	PRKCD	S1084	R1089C	1089	Missense	distal	5	no	12.466	11.901	EPSD	TCGA;ICGC;COSMIC	7.604	Down-regulation
AGC_PKC_PKCd_PRKCD_ST	P35568	IRS1	Q05655	PRKCD	S1218	S1223G	1223	Missense	distal	5	no	11.542	11.327	EPSD	TCGA;ICGC;COSMIC	7.604	Down-regulation
AGC_PKC_PKCd_PRKCD_ST	P35568	IRS1	Q05655	PRKCD	T1219	S1223G	1223	Missense	distal	4	no	8.904	8.706	EPSD	TCGA;ICGC;COSMIC	7.604	Down-regulation
AGC_PKC_PKCd_PRKCD_ST	P35568	IRS1	Q05655	PRKCD	S1222	S1223G	1223	Missense	proximal	1	no	8.311	8.204	EPSD	TCGA;ICGC;COSMIC	7.604	Down-regulation
AGC_PKC_PKCd_PRKCD_ST	P35568	IRS1	Q05655	PRKCD	S1223	S1223G	1223	Missense	central	0	yes	13.549	0.000	EPSD	TCGA;ICGC;COSMIC	7.604	Loss
AGC_PKC_PKCd_PRKCD_ST	Q96A00	PPP1R14A	Q05655	PRKCD	T38	R36C	36	Missense	proximal	-2	no	11.869	5.875	PhosphoSitePlus	TCGA;ICGC;COSMIC	7.604	Loss
AGC_PKC_PKCd_PRKCD_ST	Q96A00	PPP1R14A	Q05655	PRKCD	T38	R44W	44	Missense	distal	6	no	11.869	11.778	PhosphoSitePlus	TCGA;ICGC;COSMIC	7.604	Down-regulation
AGC_PKC_PKCd_PRKCD_ST	Q96A00	PPP1R14A	Q05655	PRKCD	S128	P129T	129	Missense	proximal	1	no	8.699	8.662	EPSD	TCGA;COSMIC	7.604	Down-regulation
AGC_PKC_PKCd_PRKCD_ST	Q00535	CDK5	Q05655	PRKCD	T77	D73N	73	Missense	distal	-4	no	8.760	8.785	PhosphoSitePlus	TCGA;ICGC;COSMIC	7.604	Up-regulation
AGC_PKC_PKCd_PRKCD_ST	P10588	NR2F6	Q05655	PRKCD	S83	I84V	84	Missense	proximal	1	no	15.568	15.576	PhosphoSitePlus	TCGA;ICGC;COSMIC	7.604	Up-regulation
AGC_PKC_PKCd_PRKCD_ST	P40189	IL6ST	Q05655	PRKCD	S461	I467M	467	Missense	distal	6	no	9.153	9.159	EPSD	TCGA	7.604	Up-regulation
AGC_PKC_PKCd_PRKCD_ST	P40189	IL6ST	Q05655	PRKCD	S461	W457C	457	Missense	distal	-4	no	9.153	9.057	EPSD	TCGA;ICGC;COSMIC	7.604	Down-regulation
AGC_PKC_PKCd_PRKCD_ST	P40189	IL6ST	Q05655	PRKCD	T909	G914S	914	Missense	distal	5	no	7.741	7.956	EPSD	TCGA;ICGC;COSMIC	7.604	Up-regulation
AGC_PKC_PKCd_PRKCD_ST	P40189	IL6ST	Q05655	PRKCD	T909	R911W	911	Missense	proximal	2	no	7.741	1.068	EPSD	TCGA;COSMIC;GDSC;CCLE	7.604	Loss
AGC_PKC_PKCd_PRKCD_ST	Q96D96	HVCN1	Q05655	PRKCD	S63	E65K	65	Missense	proximal	2	no	4.043	9.798	EPSD	TCGA	7.604	Gain
AGC_PKC_PKCd_PRKCD_ST	P23396	RPS3	Q05655	PRKCD	S6	Q4R	4	Missense	proximal	-2	no	9.892	15.326	PhosphoSitePlus;EPSD	TCGA;ICGC;COSMIC	7.604	Up-regulation
AGC_PKC_PKCd_PRKCD_ST	O14939	PLD2	Q05655	PRKCD	T99	D95N	95	Missense	distal	-4	no	8.289	8.314	EPSD	TCGA;ICGC;COSMIC	7.604	Up-regulation
AGC_PKC_PKCd_PRKCD_ST	O14939	PLD2	Q05655	PRKCD	S155	R149W	149	Missense	distal	-6	no	8.536	9.128	EPSD	TCGA;ICGC;COSMIC	7.604	Up-regulation
AGC_PKC_PKCd_PRKCD_ST	O14939	PLD2	Q05655	PRKCD	S155	P152S	152	Missense	distal	-3	no	8.536	8.204	EPSD	TCGA;ICGC	7.604	Down-regulation
AGC_PKC_PKCd_PRKCD_ST	O14939	PLD2	Q05655	PRKCD	S213	R212C	212	Missense	proximal	-1	no	14.005	13.794	EPSD	TCGA;ICGC;COSMIC	7.604	Down-regulation
AGC_PKC_PKCd_PRKCD_ST	O14939	PLD2	Q05655	PRKCD	S213	R217H	217	Missense	distal	4	no	14.005	13.462	EPSD	TCGA;ICGC	7.604	Down-regulation
AGC_PKC_PKCd_PRKCD_ST	O14939	PLD2	Q05655	PRKCD	S213	H216Y	216	Missense	distal	3	no	14.005	13.558	EPSD	TCGA;ICGC;COSMIC	7.604	Down-regulation
AGC_PKC_PKCd_PRKCD_ST	O14939	PLD2	Q05655	PRKCD	T274	R277W	277	Missense	distal	3	no	13.611	12.189	EPSD	TCGA;ICGC;COSMIC;GDSC;CCLE	7.604	Down-regulation
AGC_PKC_PKCd_PRKCD_ST	O14939	PLD2	Q05655	PRKCD	T274	H278L	278	Missense	distal	4	no	13.611	13.518	EPSD	TCGA;ICGC;COSMIC	7.604	Down-regulation
AGC_PKC_PKCd_PRKCD_ST	O14939	PLD2	Q05655	PRKCD	S416	A419V	419	Missense	distal	3	no	7.863	7.631	EPSD	TCGA;ICGC;COSMIC	7.604	Down-regulation
AGC_PKC_PKCd_PRKCD_ST	O14939	PLD2	Q05655	PRKCD	S493	L499I	499	Missense	distal	6	no	9.471	9.461	EPSD	TCGA;ICGC;COSMIC	7.604	Down-regulation
AGC_PKC_PKCd_PRKCD_ST	O14939	PLD2	Q05655	PRKCD	S814	S814N	814	Missense	central	0	yes	10.890	0.000	EPSD	TCGA;ICGC;COSMIC	7.604	Loss
AGC_PKC_PKCd_PRKCD_ST	O95817	BAG3	Q05655	PRKCD	S136	S136L	136	Missense	central	0	yes	8.017	0.000	EPSD	TCGA;ICGC;COSMIC	7.604	Loss
AGC_PKC_PKCd_PRKCD_ST	O95817	BAG3	Q05655	PRKCD	S136	A129V	129	Missense	distal	-7	no	8.017	8.011	EPSD	TCGA;ICGC;COSMIC	7.604	Down-regulation
AGC_PKC_PKCd_PRKCD_ST	O95817	BAG3	Q05655	PRKCD	S173	R170W	170	Missense	distal	-3	no	8.090	2.794	EPSD	TCGA;ICGC;COSMIC	7.604	Loss
AGC_PKC_PKCd_PRKCD_ST	O95817	BAG3	Q05655	PRKCD	S191	R193K	193	Missense	proximal	2	no	9.348	8.170	EPSD	TCGA;ICGC;COSMIC	7.604	Down-regulation
AGC_PKC_PKCd_PRKCD_ST	O95817	BAG3	Q05655	PRKCD	S191	S194N	194	Missense	distal	3	no	9.348	9.076	EPSD	TCGA;ICGC	7.604	Down-regulation
AGC_PKC_PKCd_PRKCD_ST	O95817	BAG3	Q05655	PRKCD	S264	R261Q	261	Missense	distal	-3	no	8.309	3.151	EPSD	TCGA;ICGC;COSMIC	7.604	Loss
AGC_PKC_PKCd_PRKCD_ST	O95817	BAG3	Q05655	PRKCD	S269	R276L	276	Missense	distal	7	no	7.782	7.659	EPSD	TCGA;ICGC;COSMIC	7.604	Down-regulation
AGC_PKC_PKCd_PRKCD_ST	O95817	BAG3	Q05655	PRKCD	S279	R276L	276	Missense	distal	-3	no	9.528	4.342	EPSD	TCGA;ICGC;COSMIC	7.604	Loss
AGC_PKC_PKCd_PRKCD_ST	O95817	BAG3	Q05655	PRKCD	S359	V364A	364	Missense	distal	5	no	8.570	8.691	EPSD	TCGA;ICGC	7.604	Up-regulation
AGC_PKC_PKCd_PRKCD_ST	O95817	BAG3	Q05655	PRKCD	S359	V362A	362	Missense	distal	3	no	8.570	8.803	EPSD	TCGA;ICGC;COSMIC	7.604	Up-regulation
AGC_PKC_PKCd_PRKCD_ST	O95817	BAG3	Q05655	PRKCD	S386	S386F	386	Missense	central	0	yes	8.821	0.000	EPSD	TCGA;ICGC;COSMIC	7.604	Loss
AGC_PKC_PKCd_PRKCD_ST	P29353	SHC1	Q05655	PRKCD	S17	L18V	18	Missense	proximal	1	no	9.086	9.045	EPSD	TCGA;COSMIC	7.604	Down-regulation
AGC_PKC_PKCd_PRKCD_ST	P29353	SHC1	Q05655	PRKCD	S17	R14W	14	Missense	distal	-3	no	9.086	3.790	EPSD	TCGA;ICGC;COSMIC	7.604	Loss
AGC_PKC_PKCd_PRKCD_ST	P29353	SHC1	Q05655	PRKCD	S139	R146Q	146	Missense	distal	7	no	9.770	9.680	EPSD	TCGA;COSMIC	7.604	Down-regulation
AGC_PKC_PKCd_PRKCD_ST	P29353	SHC1	Q05655	PRKCD	S139	H137L	137	Missense	proximal	-2	no	9.770	8.613	EPSD	TCGA;COSMIC	7.604	Down-regulation
AGC_PKC_PKCd_PRKCD_ST	P29353	SHC1	Q05655	PRKCD	T206	T206P	206	Missense	central	0	yes	10.677	0.000	EPSD	TCGA;ICGC;COSMIC	7.604	Loss
AGC_PKC_PKCd_PRKCD_ST	P29353	SHC1	Q05655	PRKCD	T206	A205V	205	Missense	proximal	-1	no	10.677	10.628	EPSD	TCGA;COSMIC	7.604	Down-regulation
AGC_PKC_PKCd_PRKCD_ST	Q15717	ELAVL1	Q05655	PRKCD	S88	T90P	90	Missense	proximal	2	no	7.282	7.719	EPSD	TCGA;ICGC;COSMIC	7.604	Gain
AGC_PKC_PKCd_PRKCD_ST	Q15717	ELAVL1	Q05655	PRKCD	S94	T90P	90	Missense	distal	-4	no	7.889	7.859	EPSD	TCGA;ICGC;COSMIC	7.604	Down-regulation
AGC_PKC_PKCd_PRKCD_ST	Q15717	ELAVL1	Q05655	PRKCD	S99	I103M	103	Missense	distal	4	no	7.638	7.714	EPSD	TCGA;ICGC;COSMIC	7.604	Up-regulation
AGC_PKC_PKCd_PRKCD_ST	Q15717	ELAVL1	Q05655	PRKCD	S100	I103M	103	Missense	distal	3	no	7.665	7.846	EPSD	TCGA;ICGC;COSMIC	7.604	Up-regulation
AGC_PKC_PKCd_PRKCD_ST	Q15717	ELAVL1	Q05655	PRKCD	T118	Q119H	119	Missense	proximal	1	no	8.577	8.573	EPSD	TCGA;ICGC;COSMIC	7.604	Down-regulation
AGC_PKC_PKCd_PRKCD_ST	Q15717	ELAVL1	Q05655	PRKCD	T118	G112V	112	Missense	distal	-6	no	8.577	8.629	EPSD	TCGA;ICGC;COSMIC	7.604	Up-regulation
AGC_PKC_PKCd_PRKCD_ST	Q15717	ELAVL1	Q05655	PRKCD	T118	V122L	122	Missense	distal	4	no	8.577	8.633	EPSD	TCGA;ICGC;COSMIC	7.604	Up-regulation
AGC_PKC_PKCd_PRKCD_ST	Q15717	ELAVL1	Q05655	PRKCD	T118	P114L	114	Missense	distal	-4	no	8.577	8.716	EPSD	TCGA;ICGC;COSMIC	7.604	Up-regulation
AGC_PKC_PKCd_PRKCD_ST	Q15717	ELAVL1	Q05655	PRKCD	S158	D155H	155	Missense	distal	-3	no	7.176	7.961	EPSD	TCGA	7.604	Gain
AGC_PKC_PKCd_PRKCD_ST	Q15717	ELAVL1	Q05655	PRKCD	S221	R217T	217	Missense	distal	-4	no	8.144	8.428	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	7.604	Up-regulation
AGC_PKC_PKCd_PRKCD_ST	Q15717	ELAVL1	Q05655	PRKCD	S221	D226N	226	Missense	distal	5	no	8.144	8.090	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	7.604	Down-regulation
AGC_PKC_PKCd_PRKCD_ST	O00165	HAX1	Q05655	PRKCD	S255	P259A	259	Missense	distal	4	no	11.418	11.312	EPSD	TCGA;COSMIC	7.604	Down-regulation
AGC_PKC_PKCd_PRKCD_ST	P35222	CTNNB1	Q05655	PRKCD	S37	G34R	34	Missense	distal	-3	no	4.243	9.452	EPSD	TCGA;COSMIC	7.604	Gain
AGC_PKC_PKCd_PRKCD_ST	P35222	CTNNB1	Q05655	PRKCD	S47	S45F	45	Missense	proximal	-2	no	7.734	7.210	EPSD	TCGA;COSMIC;GDSC;CCLE	7.604	Loss
AGC_PKC_PKCd_PRKCD_ST	P35222	CTNNB1	Q05655	PRKCD	S47	S45P	45	Missense	proximal	-2	no	7.734	8.119	EPSD	TCGA;COSMIC;CCLE	7.604	Up-regulation
AGC_PKC_PKCd_PRKCD_ST	P35222	CTNNB1	Q05655	PRKCD	S47	T41A	41	Missense	distal	-6	no	7.734	7.811	EPSD	TCGA;COSMIC;GDSC;CCLE	7.604	Up-regulation
AGC_PKC_PKCd_PRKCD_ST	P35222	CTNNB1	Q05655	PRKCD	S47	T41I	41	Missense	distal	-6	no	7.734	7.962	EPSD	TCGA;COSMIC	7.604	Up-regulation
AGC_PKC_PKCd_PRKCD_ST	P35222	CTNNB1	Q05655	PRKCD	S47	S45Y	45	Missense	proximal	-2	no	7.734	5.742	EPSD	TCGA;COSMIC	7.604	Loss
AGC_PKC_PKCd_PRKCD_ST	P35222	CTNNB1	Q05655	PRKCD	S47	E54D	54	Missense	distal	7	no	7.734	7.737	EPSD	TCGA;COSMIC	7.604	Up-regulation
AGC_PKC_PKCd_PRKCD_ST	P35222	CTNNB1	Q05655	PRKCD	S47	T41N	41	Missense	distal	-6	no	7.734	7.893	EPSD	TCGA;COSMIC	7.604	Up-regulation
AGC_PKC_PKCd_PRKCD_ST	P35222	CTNNB1	Q05655	PRKCD	S47	S45C	45	Missense	proximal	-2	no	7.734	6.588	EPSD	TCGA;COSMIC;GDSC;CCLE	7.604	Loss
AGC_PKC_PKCd_PRKCD_ST	P35222	CTNNB1	Q05655	PRKCD	S179	R185G	185	Missense	distal	6	no	8.737	8.678	EPSD	TCGA;COSMIC	7.604	Down-regulation
AGC_PKC_PKCd_PRKCD_ST	P35222	CTNNB1	Q05655	PRKCD	T332	E334A	334	Missense	proximal	2	no	6.002	7.711	EPSD	TCGA;COSMIC	7.604	Gain
AGC_PKC_PKCd_PRKCD_ST	P35222	CTNNB1	Q05655	PRKCD	T332	E334K	334	Missense	proximal	2	no	6.002	11.757	EPSD	TCGA;COSMIC;GDSC;CCLE	7.604	Gain
AGC_PKC_PKCd_PRKCD_ST	P35222	CTNNB1	Q05655	PRKCD	T472	R469H	469	Missense	distal	-3	no	11.443	7.188	EPSD	TCGA;COSMIC	7.604	Loss
AGC_PKC_PKCd_PRKCD_ST	P35222	CTNNB1	Q05655	PRKCD	T472	R474Q	474	Missense	proximal	2	no	11.443	4.653	EPSD	TCGA;GDSC;CCLE	7.604	Loss
AGC_PKC_PKCd_PRKCD_ST	P35222	CTNNB1	Q05655	PRKCD	T547	R542H	542	Missense	distal	-5	no	10.676	10.340	EPSD	TCGA;COSMIC	7.604	Down-regulation
AGC_PKC_PKCd_PRKCD_ST	P35222	CTNNB1	Q05655	PRKCD	T547	M553V	553	Missense	distal	6	no	10.676	10.674	EPSD	TCGA;COSMIC	7.604	Down-regulation
AGC_PKC_PKCd_PRKCD_ST	P35222	CTNNB1	Q05655	PRKCD	T547	V541A	541	Missense	distal	-6	no	10.676	10.551	EPSD	TCGA;COSMIC	7.604	Down-regulation
AGC_PKC_PKCd_PRKCD_ST	P35222	CTNNB1	Q05655	PRKCD	S552	M553V	553	Missense	proximal	1	no	13.381	13.379	EPSD	TCGA;COSMIC	7.604	Down-regulation
AGC_PKC_PKCd_PRKCD_ST	P35222	CTNNB1	Q05655	PRKCD	S675	S681F	681	Missense	distal	6	no	11.304	11.277	EPSD	TCGA	7.604	Down-regulation
AGC_PKC_PKCd_PRKCD_ST	P35222	CTNNB1	Q05655	PRKCD	S715	R717H	717	Missense	proximal	2	no	10.409	4.848	PhosphoSitePlus	TCGA;COSMIC	7.604	Loss
AGC_PKC_PKCd_PRKCD_ST	P35222	CTNNB1	Q05655	PRKCD	S715	P714R	714	Missense	proximal	-1	no	10.409	10.524	PhosphoSitePlus	TCGA;COSMIC	7.604	Up-regulation
AGC_PKC_PKCd_PRKCD_ST	P35222	CTNNB1	Q05655	PRKCD	S715	P714L	714	Missense	proximal	-1	no	10.409	10.333	PhosphoSitePlus	TCGA;COSMIC	7.604	Down-regulation
AGC_PKC_PKCd_PRKCD_ST	Q96C90	PPP1R14B	Q05655	PRKCD	T57	V50L	50	Missense	distal	-7	no	8.969	8.970	PhosphoSitePlus	TCGA;ICGC;COSMIC	7.604	Up-regulation
AGC_PKC_PKCd_PRKCD_ST	Q96C90	PPP1R14B	Q05655	PRKCD	S142	Q145H	145	Missense	distal	3	no	8.494	8.683	EPSD	TCGA;COSMIC	7.604	Up-regulation
AGC_PKC_PKCd_PRKCD_ST	P49841	GSK3B	Q05655	PRKCD	S13	Q19R	19	Missense	distal	6	no	9.596	9.643	EPSD	TCGA	7.604	Up-regulation
AGC_PKC_PKCd_PRKCD_ST	P49841	GSK3B	Q05655	PRKCD	S21	Q19R	19	Missense	proximal	-2	no	4.209	9.644	EPSD	TCGA	7.604	Gain
AGC_PKC_PKCd_PRKCD_ST	P49841	GSK3B	Q05655	PRKCD	S25	Q19R	19	Missense	distal	-6	no	10.292	9.990	EPSD	TCGA	7.604	Down-regulation
AGC_PKC_PKCd_PRKCD_ST	P49841	GSK3B	Q05655	PRKCD	S25	S25N	25	Missense	central	0	yes	10.292	0.000	EPSD	TCGA;ICGC	7.604	Loss
AGC_PKC_PKCd_PRKCD_ST	P49841	GSK3B	Q05655	PRKCD	S25	A22S	22	Missense	distal	-3	no	10.292	10.056	EPSD	TCGA;ICGC	7.604	Down-regulation
AGC_PKC_PKCd_PRKCD_ST	P49841	GSK3B	Q05655	PRKCD	S147	R148G	148	Missense	proximal	1	no	8.102	7.901	EPSD	TCGA;ICGC;COSMIC	7.604	Down-regulation
AGC_PKC_PKCd_PRKCD_ST	P40763	STAT3	Q05655	PRKCD	T412	S405F	405	Missense	distal	-7	no	11.390	11.379	EPSD	TCGA;ICGC;COSMIC	7.604	Down-regulation
AGC_PKC_PKCd_PRKCD_ST	P40763	STAT3	Q05655	PRKCD	T412	H410R	410	Missense	proximal	-2	no	11.390	16.365	EPSD	TCGA;ICGC;COSMIC	7.604	Up-regulation
AGC_PKC_PKCd_PRKCD_ST	P40763	STAT3	Q05655	PRKCD	T412	A406V	406	Missense	distal	-6	no	11.390	11.514	EPSD	TCGA;ICGC;COSMIC;GDSC;CCLE	7.604	Up-regulation
AGC_PKC_PKCd_PRKCD_ST	P40763	STAT3	Q05655	PRKCD	S691	Y686D	686	Missense	distal	-5	no	7.798	7.894	EPSD	TCGA;ICGC	7.604	Up-regulation
AGC_PKC_PKCd_PRKCD_ST	P40763	STAT3	Q05655	PRKCD	S727	R729H	729	Missense	proximal	2	no	8.961	3.400	PhosphoSitePlus	TCGA;ICGC;COSMIC;GDSC;CCLE	7.604	Loss
AGC_PKC_PKCd_PRKCD_ST	P40763	STAT3	Q05655	PRKCD	S727	P725L	725	Missense	proximal	-2	no	8.961	7.291	PhosphoSitePlus	TCGA;ICGC;COSMIC	7.604	Loss
AGC_PKC_PKCd_PRKCD_ST	O00429	DNM1L	Q05655	PRKCD	S637	R639Q	639	Missense	proximal	2	no	18.032	11.243	EPSD	TCGA;COSMIC	7.604	Down-regulation
AGC_PKC_PKCd_PRKCD_ST	O00429	DNM1L	Q05655	PRKCD	S637	K635E	635	Missense	proximal	-2	no	18.032	13.052	EPSD	TCGA;COSMIC	7.604	Down-regulation
AGC_PKC_PKCd_PRKCD_ST	Q09472	EP300	Q05655	PRKCD	S12	K14Q	14	Missense	proximal	2	no	11.076	5.464	EPSD	TCGA;ICGC;COSMIC	7.604	Loss
AGC_PKC_PKCd_PRKCD_ST	Q09472	EP300	Q05655	PRKCD	S12	K17E	17	Missense	distal	5	no	11.076	10.638	EPSD	TCGA;ICGC;COSMIC	7.604	Down-regulation
AGC_PKC_PKCd_PRKCD_ST	Q09472	EP300	Q05655	PRKCD	S12	E7G	7	Missense	distal	-5	no	11.076	11.047	EPSD	TCGA;ICGC;COSMIC	7.604	Down-regulation
AGC_PKC_PKCd_PRKCD_ST	Q09472	EP300	Q05655	PRKCD	S19	K14Q	14	Missense	distal	-5	no	9.230	8.906	EPSD	TCGA;ICGC;COSMIC	7.604	Down-regulation
AGC_PKC_PKCd_PRKCD_ST	Q09472	EP300	Q05655	PRKCD	S19	K17E	17	Missense	proximal	-2	no	9.230	4.250	EPSD	TCGA;ICGC;COSMIC	7.604	Loss
AGC_PKC_PKCd_PRKCD_ST	Q09472	EP300	Q05655	PRKCD	S19	A25P	25	Missense	distal	6	no	9.230	9.243	EPSD	TCGA;ICGC;COSMIC	7.604	Up-regulation
AGC_PKC_PKCd_PRKCD_ST	Q09472	EP300	Q05655	PRKCD	S19	P21A	21	Missense	proximal	2	no	9.230	9.826	EPSD	TCGA;ICGC;COSMIC	7.604	Up-regulation
AGC_PKC_PKCd_PRKCD_ST	Q09472	EP300	Q05655	PRKCD	S20	K14Q	14	Missense	distal	-6	no	8.222	8.574	EPSD	TCGA;ICGC;COSMIC	7.604	Up-regulation
AGC_PKC_PKCd_PRKCD_ST	Q09472	EP300	Q05655	PRKCD	S20	K17E	17	Missense	distal	-3	no	8.222	3.836	EPSD	TCGA;ICGC;COSMIC	7.604	Loss
AGC_PKC_PKCd_PRKCD_ST	Q09472	EP300	Q05655	PRKCD	S20	A25P	25	Missense	distal	5	no	8.222	8.390	EPSD	TCGA;ICGC;COSMIC	7.604	Up-regulation
AGC_PKC_PKCd_PRKCD_ST	Q09472	EP300	Q05655	PRKCD	S20	P21A	21	Missense	proximal	1	no	8.222	8.122	EPSD	TCGA;ICGC;COSMIC	7.604	Down-regulation
AGC_PKC_PKCd_PRKCD_ST	Q09472	EP300	Q05655	PRKCD	S89	N94S	94	Missense	distal	5	no	9.743	9.961	PhosphoSitePlus	TCGA;ICGC;COSMIC	7.604	Up-regulation
AGC_PKC_PKCd_PRKCD_ST	Q09472	EP300	Q05655	PRKCD	S89	L84S	84	Missense	distal	-5	no	9.743	9.899	PhosphoSitePlus	TCGA;COSMIC	7.604	Up-regulation
AGC_PKC_PKCd_PRKCD_ST	Q09472	EP300	Q05655	PRKCD	S89	R86Q	86	Missense	distal	-3	no	9.743	4.586	PhosphoSitePlus	TCGA;ICGC	7.604	Loss
AGC_PKC_PKCd_PRKCD_ST	Q09472	EP300	Q05655	PRKCD	S395	S395F	395	Missense	central	0	yes	8.066	0.000	EPSD	TCGA;ICGC;COSMIC	7.604	Loss
AGC_PKC_PKCd_PRKCD_ST	Q09472	EP300	Q05655	PRKCD	S395	A391T	391	Missense	distal	-4	no	8.066	8.036	EPSD	TCGA;ICGC;COSMIC	7.604	Down-regulation
AGC_PKC_PKCd_PRKCD_ST	Q09472	EP300	Q05655	PRKCD	S1044	P1039L	1039	Missense	distal	-5	no	8.371	8.224	EPSD	TCGA;ICGC;COSMIC	7.604	Down-regulation
AGC_PKC_PKCd_PRKCD_ST	Q09472	EP300	Q05655	PRKCD	S1044	K1045N	1045	Missense	proximal	1	no	8.371	8.175	EPSD	TCGA;ICGC;COSMIC;CCLE	7.604	Down-regulation
AGC_PKC_PKCd_PRKCD_ST	Q09472	EP300	Q05655	PRKCD	S1643	R1645Q	1645	Missense	proximal	2	no	9.055	2.266	EPSD	TCGA;ICGC;COSMIC	7.604	Loss
AGC_PKC_PKCd_PRKCD_ST	Q09472	EP300	Q05655	PRKCD	S1730	R1737C	1737	Missense	distal	7	no	7.716	7.578	EPSD	TCGA;ICGC;COSMIC	7.604	Loss
AGC_PKC_PKCd_PRKCD_ST	Q09472	EP300	Q05655	PRKCD	S1730	I1735T	1735	Missense	distal	5	no	7.716	7.952	EPSD	TCGA;ICGC	7.604	Up-regulation
AGC_PKC_PKCd_PRKCD_ST	Q09472	EP300	Q05655	PRKCD	S1734	I1739M	1739	Missense	distal	5	no	13.068	13.143	EPSD	TCGA;ICGC;COSMIC	7.604	Up-regulation
AGC_PKC_PKCd_PRKCD_ST	Q09472	EP300	Q05655	PRKCD	S1734	R1737C	1737	Missense	distal	3	no	13.068	11.794	EPSD	TCGA;ICGC;COSMIC	7.604	Down-regulation
AGC_PKC_PKCd_PRKCD_ST	Q09472	EP300	Q05655	PRKCD	S1734	I1735T	1735	Missense	proximal	1	no	13.068	13.155	EPSD	TCGA;ICGC	7.604	Up-regulation
AGC_PKC_PKCd_PRKCD_ST	Q09472	EP300	Q05655	PRKCD	S2315	R2308C	2308	Missense	distal	-7	no	9.233	9.207	EPSD	TCGA;ICGC;COSMIC	7.604	Down-regulation
AGC_PKC_PKCd_PRKCD_ST	Q09472	EP300	Q05655	PRKCD	S2315	R2317Q	2317	Missense	proximal	2	no	9.233	2.444	EPSD	TCGA;ICGC;COSMIC	7.604	Loss
AGC_PKC_PKCd_PRKCD_ST	Q09472	EP300	Q05655	PRKCD	S2315	R2317L	2317	Missense	proximal	2	no	9.233	2.355	EPSD	TCGA;ICGC;COSMIC	7.604	Loss
AGC_PKC_PKCd_PRKCD_ST	Q09472	EP300	Q05655	PRKCD	S2320	R2317Q	2317	Missense	distal	-3	no	8.027	2.869	EPSD	TCGA;ICGC;COSMIC	7.604	Loss
AGC_PKC_PKCd_PRKCD_ST	Q09472	EP300	Q05655	PRKCD	S2320	P2327H	2327	Missense	distal	7	no	8.027	8.033	EPSD	TCGA;ICGC	7.604	Up-regulation
AGC_PKC_PKCd_PRKCD_ST	Q09472	EP300	Q05655	PRKCD	S2320	R2317L	2317	Missense	distal	-3	no	8.027	2.840	EPSD	TCGA;ICGC;COSMIC	7.604	Loss
AGC_PKC_PKCd_PRKCD_ST	Q09472	EP300	Q05655	PRKCD	S2328	P2327H	2327	Missense	proximal	-1	no	10.587	10.557	EPSD	TCGA;ICGC	7.604	Down-regulation
AGC_PKC_PKCd_PRKCD_ST	Q01543	FLI1	Q05655	PRKCD	S79	S84G	84	Missense	distal	5	no	8.546	8.332	EPSD	TCGA;ICGC;COSMIC	7.604	Down-regulation
AGC_PKC_PKCd_PRKCD_ST	Q01543	FLI1	Q05655	PRKCD	S79	S79F	79	Missense	central	0	yes	8.546	0.000	EPSD	TCGA;ICGC	7.604	Loss
AGC_PKC_PKCd_PRKCD_ST	Q01543	FLI1	Q05655	PRKCD	T179	L181R	181	Missense	proximal	2	no	3.582	10.460	EPSD	TCGA;ICGC;COSMIC	7.604	Gain
AGC_PKC_PKCd_PRKCD_ST	Q01543	FLI1	Q05655	PRKCD	S215	E218Q	218	Missense	distal	3	no	13.714	13.811	EPSD	TCGA;ICGC;COSMIC	7.604	Up-regulation
AGC_PKC_PKCd_PRKCD_ST	Q01543	FLI1	Q05655	PRKCD	S215	K217T	217	Missense	proximal	2	no	13.714	8.636	EPSD	TCGA	7.604	Down-regulation
AGC_PKC_PKCd_PRKCD_ST	Q01543	FLI1	Q05655	PRKCD	S215	R213Q	213	Missense	proximal	-2	no	13.714	8.279	EPSD	TCGA;ICGC;COSMIC	7.604	Down-regulation
AGC_PKC_PKCd_PRKCD_ST	Q01543	FLI1	Q05655	PRKCD	S215	D209N	209	Missense	distal	-6	no	13.714	13.760	EPSD	TCGA;ICGC;COSMIC	7.604	Up-regulation
AGC_PKC_PKCd_PRKCD_ST	Q01543	FLI1	Q05655	PRKCD	S224	E218Q	218	Missense	distal	-6	no	8.073	8.006	EPSD	TCGA;ICGC;COSMIC	7.604	Down-regulation
AGC_PKC_PKCd_PRKCD_ST	Q01543	FLI1	Q05655	PRKCD	S224	R226K	226	Missense	proximal	2	no	8.073	6.895	EPSD	TCGA;ICGC;COSMIC	7.604	Loss
AGC_PKC_PKCd_PRKCD_ST	Q01543	FLI1	Q05655	PRKCD	S224	K217T	217	Missense	distal	-7	no	8.073	8.054	EPSD	TCGA	7.604	Down-regulation
AGC_PKC_PKCd_PRKCD_ST	Q01543	FLI1	Q05655	PRKCD	S224	G231D	231	Missense	distal	7	no	8.073	8.076	EPSD	TCGA;ICGC	7.604	Up-regulation
AGC_PKC_PKCd_PRKCD_ST	P08581	MET	Q05655	PRKCD	T1257	S1254R	1254	Missense	distal	-3	no	6.539	11.114	EPSD	TCGA;COSMIC	7.604	Gain
AGC_PKC_PKCd_PRKCD_ST	P08581	MET	Q05655	PRKCD	T1261	S1254R	1254	Missense	distal	-7	no	8.120	8.132	EPSD	TCGA;COSMIC	7.604	Up-regulation
AGC_PKC_PKCd_PRKCD_ST	Q9UQ80	PA2G4	Q05655	PRKCD	T279	D274N	274	Missense	distal	-5	no	8.141	8.118	EPSD	TCGA;ICGC;COSMIC	7.604	Down-regulation
AGC_PKC_PKCd_PRKCD_ST	Q9UQ80	PA2G4	Q05655	PRKCD	T279	R272C	272	Missense	distal	-7	no	8.141	8.115	EPSD	TCGA;ICGC;COSMIC	7.604	Down-regulation
AGC_PKC_PKCd_PRKCD_ST	Q9UQ80	PA2G4	Q05655	PRKCD	T279	P277L	277	Missense	proximal	-2	no	8.141	6.471	EPSD	TCGA	7.604	Loss
AGC_PKC_PKCd_PRKCD_ST	Q9UQ80	PA2G4	Q05655	PRKCD	T279	A282T	282	Missense	distal	3	no	8.141	8.065	EPSD	TCGA;ICGC	7.604	Down-regulation
AGC_PKC_PKCd_PRKCD_ST	Q9UQ80	PA2G4	Q05655	PRKCD	S335	P337R	337	Missense	proximal	2	no	4.189	10.007	EPSD	TCGA;ICGC;COSMIC	7.604	Gain
AGC_PKC_PKCd_PRKCD_ST	Q9UQ80	PA2G4	Q05655	PRKCD	S363	Q367H	367	Missense	distal	4	no	10.325	10.371	EPSD	TCGA;ICGC;COSMIC	7.604	Up-regulation
AGC_PKC_PKCd_PRKCD_ST	Q9UQ80	PA2G4	Q05655	PRKCD	S363	R364Q	364	Missense	proximal	1	no	10.325	10.195	EPSD	TCGA;ICGC;COSMIC	7.604	Down-regulation
AGC_PKC_PKCd_PRKCD_ST	Q9UQ80	PA2G4	Q05655	PRKCD	T366	Q367H	367	Missense	proximal	1	no	12.737	12.733	EPSD	TCGA;ICGC;COSMIC	7.604	Down-regulation
AGC_PKC_PKCd_PRKCD_ST	Q9UQ80	PA2G4	Q05655	PRKCD	T366	R364Q	364	Missense	proximal	-2	no	12.737	7.302	EPSD	TCGA;ICGC;COSMIC	7.604	Loss
AGC_PKC_PKCd_PRKCD_ST	Q9UQ80	PA2G4	Q05655	PRKCD	T366	K372N	372	Missense	distal	6	no	12.737	12.674	EPSD	TCGA;ICGC;COSMIC	7.604	Down-regulation
AGC_PKC_PKCd_PRKCD_ST	Q9UQ80	PA2G4	Q05655	PRKCD	S375	E379D	379	Missense	distal	4	no	11.600	11.575	EPSD	TCGA;ICGC;COSMIC	7.604	Down-regulation
AGC_PKC_PKCd_PRKCD_ST	Q9UQ80	PA2G4	Q05655	PRKCD	S375	K372N	372	Missense	distal	-3	no	11.600	7.496	EPSD	TCGA;ICGC;COSMIC	7.604	Loss
AGC_PKC_PKCd_PRKCD_ST	P04040	CAT	Q05655	PRKCD	S114	R112W	112	Missense	proximal	-2	no	8.515	2.261	EPSD	TCGA;ICGC;COSMIC;GDSC	7.604	Loss
AGC_PKC_PKCd_PRKCD_ST	P04040	CAT	Q05655	PRKCD	S114	F113L	113	Missense	proximal	-1	no	8.515	8.505	EPSD	TCGA;ICGC	7.604	Down-regulation
AGC_PKC_PKCd_PRKCD_ST	P04040	CAT	Q05655	PRKCD	T115	R112W	112	Missense	distal	-3	no	8.076	2.779	EPSD	TCGA;ICGC;COSMIC;GDSC	7.604	Loss
AGC_PKC_PKCd_PRKCD_ST	P04040	CAT	Q05655	PRKCD	T115	F113L	113	Missense	proximal	-2	no	8.076	7.315	EPSD	TCGA;ICGC	7.604	Loss
AGC_PKC_PKCd_PRKCD_ST	P04040	CAT	Q05655	PRKCD	S167	P172S	172	Missense	distal	5	no	8.389	8.356	PhosphoSitePlus	TCGA;ICGC;COSMIC;CCLE	7.604	Down-regulation
AGC_PKC_PKCd_PRKCD_ST	O15350	TP73	Q05655	PRKCD	S235	G232A	232	Missense	distal	-3	no	7.238	8.108	EPSD	TCGA	7.604	Gain
AGC_PKC_PKCd_PRKCD_ST	O15350	TP73	Q05655	PRKCD	S289	R293C	293	Missense	distal	4	no	8.553	7.757	PhosphoSitePlus	TCGA;ICGC;COSMIC	7.604	Down-regulation
AGC_PKC_PKCd_PRKCD_ST	O15350	TP73	Q05655	PRKCD	S289	A296T	296	Missense	distal	7	no	8.553	8.571	PhosphoSitePlus	TCGA;ICGC;COSMIC	7.604	Up-regulation
AGC_PKC_PKCd_PRKCD_ST	O15350	TP73	Q05655	PRKCD	S289	S289F	289	Missense	central	0	yes	8.553	0.000	PhosphoSitePlus	TCGA;ICGC;COSMIC	7.604	Loss
AGC_PKC_PKCd_PRKCD_ST	O15350	TP73	Q05655	PRKCD	S289	R293S	293	Missense	distal	4	no	8.553	8.083	PhosphoSitePlus	TCGA;ICGC;COSMIC	7.604	Down-regulation
AGC_PKC_PKCd_PRKCD_ST	O15350	TP73	Q05655	PRKCD	S326	A324V	324	Missense	proximal	-2	no	9.334	8.703	EPSD	TCGA;ICGC;COSMIC	7.604	Down-regulation
AGC_PKC_PKCd_PRKCD_ST	O15350	TP73	Q05655	PRKCD	S388	Q391R	391	Missense	distal	3	no	7.254	8.332	EPSD	TCGA;ICGC;COSMIC;CCLE	7.604	Gain
AGC_PKC_PKCd_PRKCD_ST	P12931	SRC	Q05655	PRKCD	S12	S6N	6	Missense	distal	-6	no	14.804	15.004	PhosphoSitePlus	TCGA;ICGC;COSMIC	7.604	Up-regulation
AGC_PKC_PKCd_PRKCD_ST	P12931	SRC	Q05655	PRKCD	S12	R14W	14	Missense	proximal	2	no	14.804	8.131	PhosphoSitePlus	TCGA;ICGC;COSMIC	7.604	Down-regulation
AGC_PKC_PKCd_PRKCD_ST	P12931	SRC	Q05655	PRKCD	S17	R14W	14	Missense	distal	-3	no	14.401	9.104	EPSD	TCGA;ICGC;COSMIC	7.604	Down-regulation
AGC_PKC_PKCd_PRKCD_ST	P12931	SRC	Q05655	PRKCD	S104	T101A	101	Missense	distal	-3	no	7.119	7.873	EPSD	TCGA;ICGC;COSMIC	7.604	Gain
AGC_PKC_PKCd_PRKCD_ST	P12931	SRC	Q05655	PRKCD	S180	E181K	181	Missense	proximal	1	no	8.337	8.498	EPSD	TCGA;ICGC;COSMIC	7.604	Up-regulation
AGC_PKC_PKCd_PRKCD_ST	P12931	SRC	Q05655	PRKCD	S269	S269L	269	Missense	central	0	yes	15.167	0.000	EPSD	TCGA;ICGC;COSMIC	7.604	Loss
AGC_PKC_PKCd_PRKCD_ST	P12931	SRC	Q05655	PRKCD	S269	R271Q	271	Missense	proximal	2	no	15.167	8.377	EPSD	TCGA;ICGC;COSMIC	7.604	Down-regulation
AGC_PKC_PKCd_PRKCD_ST	P12931	SRC	Q05655	PRKCD	S269	P266H	266	Missense	distal	-3	no	15.167	15.155	EPSD	TCGA;ICGC;COSMIC	7.604	Down-regulation
AGC_PKC_PKCd_PRKCD_ST	P12931	SRC	Q05655	PRKCD	T443	S450F	450	Missense	distal	7	no	10.085	10.037	EPSD	TCGA;ICGC;COSMIC	7.604	Down-regulation
AGC_PKC_PKCd_PRKCD_ST	P52757	CHN2	Q05655	PRKCD	S85	R83T	83	Missense	proximal	-2	no	13.564	7.601	EPSD	TCGA;COSMIC	7.604	Loss
AGC_PKC_PKCd_PRKCD_ST	P52757	CHN2	Q05655	PRKCD	S85	R87Q	87	Missense	proximal	2	no	13.564	6.774	EPSD	TCGA;COSMIC	7.604	Loss
AGC_PKC_PKCd_PRKCD_ST	P52757	CHN2	Q05655	PRKCD	S85	G90E	90	Missense	distal	5	no	13.564	13.630	EPSD	TCGA;COSMIC	7.604	Up-regulation
AGC_PKC_PKCd_PRKCD_ST	P52757	CHN2	Q05655	PRKCD	S85	R87W	87	Missense	proximal	2	no	13.564	6.891	EPSD	TCGA;COSMIC	7.604	Loss
AGC_PKC_PKCd_PRKCD_ST	P52757	CHN2	Q05655	PRKCD	S167	R169G	169	Missense	proximal	2	no	11.819	5.488	EPSD	TCGA;COSMIC	7.604	Loss
AGC_PKC_PKCd_PRKCD_ST	P52757	CHN2	Q05655	PRKCD	S171	R169G	169	Missense	proximal	-2	no	12.251	6.487	PhosphoSitePlus	TCGA;COSMIC	7.604	Loss
AGC_PKC_PKCd_PRKCD_ST	P30086	PEBP1	Q05655	PRKCD	S52	L58V	58	Missense	distal	6	no	7.624	7.619	EPSD	TCGA;ICGC;COSMIC	7.604	Down-regulation
AGC_PKC_PKCd_PRKCD_ST	P30086	PEBP1	Q05655	PRKCD	S52	G57V	57	Missense	distal	5	no	7.624	7.582	EPSD	TCGA;ICGC;COSMIC	7.604	Loss
AGC_PKC_PKCd_PRKCD_ST	P30086	PEBP1	Q05655	PRKCD	S52	S54L	54	Missense	proximal	2	no	7.624	6.810	EPSD	TCGA;ICGC;COSMIC	7.604	Loss
AGC_PKC_PKCd_PRKCD_ST	P30086	PEBP1	Q05655	PRKCD	S75	K80N	80	Missense	distal	5	no	7.860	7.352	EPSD	TCGA;ICGC;COSMIC	7.604	Loss
AGC_PKC_PKCd_PRKCD_ST	P30086	PEBP1	Q05655	PRKCD	S75	P79L	79	Missense	distal	4	no	7.860	7.655	EPSD	TCGA;ICGC;COSMIC	7.604	Down-regulation
AGC_PKC_PKCd_PRKCD_ST	P30086	PEBP1	Q05655	PRKCD	S139	L138F	138	Missense	proximal	-1	no	8.671	8.681	EPSD	TCGA;ICGC;COSMIC	7.604	Up-regulation
AGC_PKC_PKCd_PRKCD_ST	P30086	PEBP1	Q05655	PRKCD	S139	R141Q	141	Missense	proximal	2	no	8.671	1.882	EPSD	TCGA;ICGC	7.604	Loss
AGC_PKC_PKCd_PRKCD_ST	P30086	PEBP1	Q05655	PRKCD	S153	G147V	147	Missense	distal	-6	no	14.402	14.453	PhosphoSitePlus	TCGA;ICGC;COSMIC	7.604	Up-regulation
AGC_PKC_PKCd_PRKCD_ST	Q8IV61	RASGRP3	Q05655	PRKCD	T133	R131I	131	Missense	proximal	-2	no	19.126	12.401	PhosphoSitePlus	TCGA;ICGC	7.604	Down-regulation
AGC_PKC_PKCd_PRKCD_ST	Q8IV61	RASGRP3	Q05655	PRKCD	T133	R135K	135	Missense	proximal	2	no	19.126	17.949	PhosphoSitePlus	TCGA;ICGC;COSMIC	7.604	Down-regulation
AGC_PKC_PKCd_PRKCD_ST	Q8IV61	RASGRP3	Q05655	PRKCD	T133	R131K	131	Missense	proximal	-2	no	19.126	17.880	PhosphoSitePlus	TCGA;ICGC;COSMIC	7.604	Down-regulation
AGC_PKC_PKCd_PRKCD_ST	Q8IV61	RASGRP3	Q05655	PRKCD	T133	D127N	127	Missense	distal	-6	no	19.126	19.172	PhosphoSitePlus	TCGA;ICGC;COSMIC	7.604	Up-regulation
AGC_PKC_PKCd_PRKCD_ST	Q8IV61	RASGRP3	Q05655	PRKCD	T133	Q134H	134	Missense	proximal	1	no	19.126	19.122	PhosphoSitePlus	TCGA;ICGC;COSMIC	7.604	Down-regulation
AGC_PKC_PKCd_PRKCD_ST	Q8IV61	RASGRP3	Q05655	PRKCD	S552	P551R	551	Missense	proximal	-1	no	8.325	8.440	EPSD	TCGA;ICGC;COSMIC	7.604	Up-regulation
AGC_PKC_PKCd_PRKCD_ST	Q8IV61	RASGRP3	Q05655	PRKCD	S554	P551R	551	Missense	distal	-3	no	5.338	9.582	EPSD	TCGA;ICGC;COSMIC	7.604	Gain
AGC_PKC_PKCd_PRKCD_ST	Q8IV61	RASGRP3	Q05655	PRKCD	S597	R599H	599	Missense	proximal	2	no	9.497	3.937	EPSD	TCGA;ICGC;GDSC;CCLE	7.604	Loss
AGC_PKC_PKCd_PRKCD_ST	Q8IV61	RASGRP3	Q05655	PRKCD	S597	G596S	596	Missense	proximal	-1	no	9.497	9.600	EPSD	TCGA;ICGC;COSMIC	7.604	Up-regulation
AGC_PKC_PKCd_PRKCD_ST	Q8IV61	RASGRP3	Q05655	PRKCD	S598	R599H	599	Missense	proximal	1	no	7.876	7.742	EPSD	TCGA;ICGC;GDSC;CCLE	7.604	Down-regulation
AGC_PKC_PKCd_PRKCD_ST	Q8IV61	RASGRP3	Q05655	PRKCD	S598	G596S	596	Missense	proximal	-2	no	7.876	8.792	EPSD	TCGA;ICGC;COSMIC	7.604	Up-regulation
CAMK_PIM_PIM2_ST	P14618	PKM	Q9P1W9	PIM2	S37	R43P	43	Missense	distal	6	no	4.471	4.738	EPSD	TCGA;ICGC;COSMIC	4.322	Up-regulation
CAMK_PIM_PIM2_ST	P14618	PKM	Q9P1W9	PIM2	S37	R32C	32	Missense	distal	-5	no	4.471	1.462	EPSD	TCGA;ICGC;COSMIC	4.322	Loss
CAMK_PIM_PIM2_ST	P14618	PKM	Q9P1W9	PIM2	S37	R32H	32	Missense	distal	-5	no	4.471	2.023	EPSD	TCGA;ICGC;COSMIC	4.322	Loss
CAMK_PIM_PIM2_ST	P14618	PKM	Q9P1W9	PIM2	S127	G128S	128	Missense	proximal	1	no	5.576	5.565	EPSD	TCGA;ICGC;COSMIC	4.322	Down-regulation
CAMK_PIM_PIM2_ST	P14618	PKM	Q9P1W9	PIM2	T454	I450M	450	Missense	distal	-4	no	11.856	11.933	PhosphoSitePlus	TCGA;COSMIC	4.322	Up-regulation
CAMK_PIM_PIM2_ST	P14618	PKM	Q9P1W9	PIM2	T454	R447H	447	Missense	distal	-7	no	11.856	11.529	PhosphoSitePlus	TCGA;COSMIC	4.322	Down-regulation
CAMK_PIM_PIM2_ST	P52789	HK2	Q9P1W9	PIM2	T153	P157L	157	Missense	distal	4	no	3.871	4.631	EPSD	TCGA;COSMIC	4.322	Gain
CAMK_PIM_PIM2_ST	P38936	CDKN1A	Q9P1W9	PIM2	S31	D33N	33	Missense	proximal	2	no	4.430	4.390	EPSD	TCGA;ICGC;COSMIC	4.322	Down-regulation
CAMK_PIM_PIM2_ST	P38936	CDKN1A	Q9P1W9	PIM2	S31	R32H	32	Missense	proximal	1	no	4.430	4.726	EPSD	TCGA;ICGC;COSMIC	4.322	Up-regulation
CAMK_PIM_PIM2_ST	P38936	CDKN1A	Q9P1W9	PIM2	S31	A36V	36	Missense	distal	5	no	4.430	4.310	EPSD	TCGA;ICGC;COSMIC	4.322	Loss
CAMK_PIM_PIM2_ST	P38936	CDKN1A	Q9P1W9	PIM2	S98	R94W	94	Missense	distal	-4	no	5.286	5.412	EPSD	TCGA;ICGC;COSMIC	4.322	Up-regulation
CAMK_PIM_PIM2_ST	P38936	CDKN1A	Q9P1W9	PIM2	S98	R93S	93	Missense	distal	-5	no	5.286	1.853	EPSD	TCGA;ICGC;COSMIC	4.322	Loss
CAMK_PIM_PIM2_ST	P38936	CDKN1A	Q9P1W9	PIM2	S98	R94P	94	Missense	distal	-4	no	5.286	5.285	EPSD	TCGA;ICGC;COSMIC	4.322	Down-regulation
CAMK_PIM_PIM2_ST	P38936	CDKN1A	Q9P1W9	PIM2	S98	P95S	95	Missense	distal	-3	no	5.286	4.601	EPSD	TCGA;ICGC;COSMIC	4.322	Down-regulation
CAMK_PIM_PIM2_ST	P38936	CDKN1A	Q9P1W9	PIM2	T145	D149H	149	Missense	distal	4	no	11.610	12.021	PhosphoSitePlus;EPSD	TCGA;ICGC;COSMIC	4.322	Up-regulation
CAMK_PIM_PIM2_ST	P38936	CDKN1A	Q9P1W9	PIM2	T145	R142W	142	Missense	distal	-3	no	11.610	9.792	PhosphoSitePlus;EPSD	TCGA;ICGC;COSMIC;GDSC;CCLE	4.322	Down-regulation
CAMK_PIM_PIM2_ST	P38936	CDKN1A	Q9P1W9	PIM2	S146	S153C	153	Missense	distal	7	no	9.959	9.991	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	4.322	Up-regulation
CAMK_PIM_PIM2_ST	P38936	CDKN1A	Q9P1W9	PIM2	S146	D149H	149	Missense	distal	3	no	9.959	9.639	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	4.322	Down-regulation
CAMK_PIM_PIM2_ST	P38936	CDKN1A	Q9P1W9	PIM2	S146	R142W	142	Missense	distal	-4	no	9.959	10.085	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC;GDSC;CCLE	4.322	Up-regulation
CAMK_PIM_PIM2_ST	P38936	CDKN1A	Q9P1W9	PIM2	S153	S153C	153	Missense	central	0	yes	4.399	0.000	EPSD	TCGA;ICGC;COSMIC	4.322	Loss
CAMK_PIM_PIM2_ST	P38936	CDKN1A	Q9P1W9	PIM2	S153	R155H	155	Missense	proximal	2	no	4.399	4.665	EPSD	TCGA;ICGC;COSMIC;CCLE	4.322	Up-regulation
CAMK_PIM_PIM2_ST	P38936	CDKN1A	Q9P1W9	PIM2	S153	D149H	149	Missense	distal	-4	no	4.399	4.295	EPSD	TCGA;ICGC;COSMIC	4.322	Loss
CAMK_PIM_PIM2_ST	P35568	IRS1	Q9P1W9	PIM2	S189	I182V	182	Missense	distal	-7	no	4.580	4.549	EPSD	TCGA;ICGC	4.322	Down-regulation
CAMK_PIM_PIM2_ST	P35568	IRS1	Q9P1W9	PIM2	S189	V195M	195	Missense	distal	6	no	4.580	4.599	EPSD	TCGA;ICGC;COSMIC	4.322	Up-regulation
CAMK_PIM_PIM2_ST	P35568	IRS1	Q9P1W9	PIM2	S189	L185R	185	Missense	distal	-4	no	4.580	4.515	EPSD	TCGA;ICGC;COSMIC	4.322	Down-regulation
CAMK_PIM_PIM2_ST	P35568	IRS1	Q9P1W9	PIM2	S193	V195M	195	Missense	proximal	2	no	5.012	4.975	EPSD	TCGA;ICGC;COSMIC	4.322	Down-regulation
CAMK_PIM_PIM2_ST	P35568	IRS1	Q9P1W9	PIM2	S270	E263K	263	Missense	distal	-7	no	5.498	5.676	EPSD	TCGA;ICGC;COSMIC	4.322	Up-regulation
CAMK_PIM_PIM2_ST	P35568	IRS1	Q9P1W9	PIM2	S270	K269N	269	Missense	proximal	-1	no	5.498	5.874	EPSD	TCGA;ICGC;COSMIC	4.322	Up-regulation
CAMK_PIM_PIM2_ST	P35568	IRS1	Q9P1W9	PIM2	S270	P266S	266	Missense	distal	-4	no	5.498	5.542	EPSD	TCGA;ICGC;COSMIC	4.322	Up-regulation
CAMK_PIM_PIM2_ST	P35568	IRS1	Q9P1W9	PIM2	S270	C276F	276	Missense	distal	6	no	5.498	5.561	EPSD	TCGA;ICGC;COSMIC	4.322	Up-regulation
CAMK_PIM_PIM2_ST	P35568	IRS1	Q9P1W9	PIM2	S270	N275S	275	Missense	distal	5	no	5.498	5.628	EPSD	TCGA;ICGC;COSMIC	4.322	Up-regulation
CAMK_PIM_PIM2_ST	P35568	IRS1	Q9P1W9	PIM2	S272	K269N	269	Missense	distal	-3	no	5.034	4.296	EPSD	TCGA;ICGC;COSMIC	4.322	Loss
CAMK_PIM_PIM2_ST	P35568	IRS1	Q9P1W9	PIM2	S272	P266S	266	Missense	distal	-6	no	5.034	4.922	EPSD	TCGA;ICGC;COSMIC	4.322	Down-regulation
CAMK_PIM_PIM2_ST	P35568	IRS1	Q9P1W9	PIM2	S272	C276F	276	Missense	distal	4	no	5.034	5.738	EPSD	TCGA;ICGC;COSMIC	4.322	Up-regulation
CAMK_PIM_PIM2_ST	P35568	IRS1	Q9P1W9	PIM2	S272	N275S	275	Missense	distal	3	no	5.034	5.115	EPSD	TCGA;ICGC;COSMIC	4.322	Up-regulation
CAMK_PIM_PIM2_ST	P35568	IRS1	Q9P1W9	PIM2	S307	A314G	314	Missense	distal	7	no	5.185	5.319	EPSD	TCGA;ICGC;COSMIC	4.322	Up-regulation
CAMK_PIM_PIM2_ST	P35568	IRS1	Q9P1W9	PIM2	S312	A314G	314	Missense	proximal	2	no	5.068	5.119	EPSD	TCGA;ICGC;COSMIC	4.322	Up-regulation
CAMK_PIM_PIM2_ST	P35568	IRS1	Q9P1W9	PIM2	S330	S323A	323	Missense	distal	-7	no	4.131	4.446	EPSD	TCGA;ICGC;COSMIC	4.322	Gain
CAMK_PIM_PIM2_ST	P35568	IRS1	Q9P1W9	PIM2	S396	S395C	395	Missense	proximal	-1	no	4.297	4.655	EPSD	TCGA;ICGC;COSMIC	4.322	Gain
CAMK_PIM_PIM2_ST	P35568	IRS1	Q9P1W9	PIM2	S415	R411Q	411	Missense	distal	-4	no	5.097	5.115	EPSD	TCGA;ICGC	4.322	Up-regulation
CAMK_PIM_PIM2_ST	P35568	IRS1	Q9P1W9	PIM2	S433	S428L	428	Missense	distal	-5	no	3.565	4.791	EPSD	TCGA;ICGC;COSMIC	4.322	Gain
CAMK_PIM_PIM2_ST	P35568	IRS1	Q9P1W9	PIM2	S527	R520W	520	Missense	distal	-7	no	4.512	4.334	EPSD	TCGA;ICGC;COSMIC	4.322	Down-regulation
CAMK_PIM_PIM2_ST	P35568	IRS1	Q9P1W9	PIM2	S527	R522Q	522	Missense	distal	-5	no	4.512	1.289	EPSD	TCGA;ICGC;COSMIC	4.322	Loss
CAMK_PIM_PIM2_ST	P35568	IRS1	Q9P1W9	PIM2	S527	R520Q	520	Missense	distal	-7	no	4.512	4.323	EPSD	TCGA;ICGC;COSMIC	4.322	Down-regulation
CAMK_PIM_PIM2_ST	P35568	IRS1	Q9P1W9	PIM2	S736	M733I	733	Missense	distal	-3	no	4.364	4.347	EPSD	TCGA;ICGC;COSMIC	4.322	Down-regulation
CAMK_PIM_PIM2_ST	P35568	IRS1	Q9P1W9	PIM2	S736	N742D	742	Missense	distal	6	no	4.364	4.461	EPSD	TCGA;ICGC;COSMIC	4.322	Up-regulation
CAMK_PIM_PIM2_ST	P35568	IRS1	Q9P1W9	PIM2	S736	D731E	731	Missense	distal	-5	no	4.364	5.686	EPSD	TCGA;ICGC;COSMIC	4.322	Up-regulation
CAMK_PIM_PIM2_ST	P35568	IRS1	Q9P1W9	PIM2	T859	A856T	856	Missense	distal	-3	no	5.482	6.171	EPSD	TCGA;ICGC;COSMIC	4.322	Up-regulation
CAMK_PIM_PIM2_ST	P35568	IRS1	Q9P1W9	PIM2	T859	R857W	857	Missense	proximal	-2	no	5.482	4.575	EPSD	TCGA;ICGC;COSMIC	4.322	Down-regulation
CAMK_PIM_PIM2_ST	P35568	IRS1	Q9P1W9	PIM2	T938	E939Q	939	Missense	proximal	1	no	4.540	4.149	EPSD	TCGA;ICGC;COSMIC	4.322	Loss
CAMK_PIM_PIM2_ST	P35568	IRS1	Q9P1W9	PIM2	T938	E939K	939	Missense	proximal	1	no	4.540	3.987	EPSD	TCGA;ICGC;COSMIC	4.322	Loss
CAMK_PIM_PIM2_ST	P35568	IRS1	Q9P1W9	PIM2	S1011	S1005L	1005	Missense	distal	-6	no	5.042	4.980	EPSD	TCGA;ICGC	4.322	Down-regulation
CAMK_PIM_PIM2_ST	P35568	IRS1	Q9P1W9	PIM2	S1011	R1016Q	1016	Missense	distal	5	no	5.042	4.965	EPSD	TCGA;ICGC;COSMIC	4.322	Down-regulation
CAMK_CAMK2_CAMK2A_ST	P24588	AKAP5	Q9UQM7	CAMK2A	T87	K83E	83	Missense	distal	-4	no	7.285	7.333	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	4.810	Up-regulation
CAMK_CAMK2_CAMK2A_ST	P24588	AKAP5	Q9UQM7	CAMK2A	T87	R88C	88	Missense	proximal	1	no	7.285	7.254	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	4.810	Down-regulation
CAMK_CAMK2_CAMK2A_ST	P24588	AKAP5	Q9UQM7	CAMK2A	S92	S95L	95	Missense	distal	3	no	7.739	7.426	PhosphoSitePlus;EPSD	TCGA;ICGC;COSMIC	4.810	Down-regulation
CAMK_CAMK2_CAMK2A_ST	P24588	AKAP5	Q9UQM7	CAMK2A	S92	R88C	88	Missense	distal	-4	no	7.739	7.104	PhosphoSitePlus;EPSD	TCGA;ICGC;COSMIC	4.810	Down-regulation
CAMK_CAMK2_CAMK2A_ST	P24588	AKAP5	Q9UQM7	CAMK2A	S178	E184K	184	Missense	distal	6	no	5.209	5.158	EPSD	TCGA;ICGC;COSMIC	4.810	Down-regulation
CAMK_CAMK2_CAMK2A_ST	Q14524	SCN5A	Q9UQM7	CAMK2A	S11	R15S	15	Missense	distal	4	no	7.285	7.457	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	4.810	Up-regulation
CAMK_CAMK2_CAMK2A_ST	Q14524	SCN5A	Q9UQM7	CAMK2A	S11	R8W	8	Missense	distal	-3	no	7.285	-4.735	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	4.810	Loss
CAMK_CAMK2_CAMK2A_ST	Q14524	SCN5A	Q9UQM7	CAMK2A	S11	R14C	14	Missense	distal	3	no	7.285	7.022	EPSD;PhosphoSitePlus	TCGA;ICGC;GDSC;CCLE	4.810	Down-regulation
CAMK_CAMK2_CAMK2A_ST	Q14524	SCN5A	Q9UQM7	CAMK2A	S12	R15S	15	Missense	distal	3	no	5.341	5.435	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	4.810	Up-regulation
CAMK_CAMK2_CAMK2A_ST	Q14524	SCN5A	Q9UQM7	CAMK2A	S12	E19Q	19	Missense	distal	7	no	5.341	5.469	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	4.810	Up-regulation
CAMK_CAMK2_CAMK2A_ST	Q14524	SCN5A	Q9UQM7	CAMK2A	S12	R8W	8	Missense	distal	-4	no	5.341	4.650	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	4.810	Loss
CAMK_CAMK2_CAMK2A_ST	Q14524	SCN5A	Q9UQM7	CAMK2A	S12	R14C	14	Missense	proximal	2	no	5.341	4.894	EPSD;PhosphoSitePlus	TCGA;ICGC;GDSC;CCLE	4.810	Down-regulation
CAMK_CAMK2_CAMK2A_ST	Q14524	SCN5A	Q9UQM7	CAMK2A	T17	R15S	15	Missense	proximal	-2	no	8.351	8.280	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	4.810	Down-regulation
CAMK_CAMK2_CAMK2A_ST	Q14524	SCN5A	Q9UQM7	CAMK2A	T17	E19Q	19	Missense	proximal	2	no	8.351	7.221	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	4.810	Down-regulation
CAMK_CAMK2_CAMK2A_ST	Q14524	SCN5A	Q9UQM7	CAMK2A	T17	R14C	14	Missense	distal	-3	no	8.351	2.770	EPSD;PhosphoSitePlus	TCGA;ICGC;GDSC;CCLE	4.810	Loss
CAMK_CAMK2_CAMK2A_ST	Q14524	SCN5A	Q9UQM7	CAMK2A	T37	R43Q	43	Missense	distal	6	no	5.348	5.354	EPSD	TCGA;ICGC;COSMIC	4.810	Up-regulation
CAMK_CAMK2_CAMK2A_ST	Q14524	SCN5A	Q9UQM7	CAMK2A	T37	S36L	36	Missense	proximal	-1	no	5.348	5.138	EPSD	TCGA;ICGC;COSMIC	4.810	Down-regulation
CAMK_CAMK2_CAMK2A_ST	Q14524	SCN5A	Q9UQM7	CAMK2A	T37	E41K	41	Missense	distal	4	no	5.348	5.172	EPSD	TCGA;ICGC;COSMIC	4.810	Down-regulation
CAMK_CAMK2_CAMK2A_ST	Q14524	SCN5A	Q9UQM7	CAMK2A	T37	R34H	34	Missense	distal	-3	no	5.348	-0.149	EPSD	TCGA;ICGC;COSMIC	4.810	Loss
CAMK_CAMK2_CAMK2A_ST	Q14524	SCN5A	Q9UQM7	CAMK2A	S483	K477N	477	Missense	distal	-6	no	5.243	5.361	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	4.810	Up-regulation
CAMK_CAMK2_CAMK2A_ST	Q14524	SCN5A	Q9UQM7	CAMK2A	S483	R478M	478	Missense	distal	-5	no	5.243	5.227	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	4.810	Down-regulation
CAMK_CAMK2_CAMK2A_ST	Q14524	SCN5A	Q9UQM7	CAMK2A	S483	E488G	488	Missense	distal	5	no	5.243	5.121	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	4.810	Down-regulation
CAMK_CAMK2_CAMK2A_ST	Q14524	SCN5A	Q9UQM7	CAMK2A	S483	G485E	485	Missense	proximal	2	no	5.243	6.161	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	4.810	Up-regulation
CAMK_CAMK2_CAMK2A_ST	Q14524	SCN5A	Q9UQM7	CAMK2A	S483	S484L	484	Missense	proximal	1	no	5.243	5.534	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	4.810	Up-regulation
CAMK_CAMK2_CAMK2A_ST	Q14524	SCN5A	Q9UQM7	CAMK2A	S484	K477N	477	Missense	distal	-7	no	7.239	7.434	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	4.810	Up-regulation
CAMK_CAMK2_CAMK2A_ST	Q14524	SCN5A	Q9UQM7	CAMK2A	S484	R478M	478	Missense	distal	-6	no	7.239	7.202	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	4.810	Down-regulation
CAMK_CAMK2_CAMK2A_ST	Q14524	SCN5A	Q9UQM7	CAMK2A	S484	E488G	488	Missense	distal	4	no	7.239	7.012	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	4.810	Down-regulation
CAMK_CAMK2_CAMK2A_ST	Q14524	SCN5A	Q9UQM7	CAMK2A	S484	G485E	485	Missense	proximal	1	no	7.239	7.822	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	4.810	Up-regulation
CAMK_CAMK2_CAMK2A_ST	Q14524	SCN5A	Q9UQM7	CAMK2A	S484	S484L	484	Missense	central	0	yes	7.239	0.000	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	4.810	Loss
CAMK_CAMK2_CAMK2A_ST	Q14524	SCN5A	Q9UQM7	CAMK2A	S499	P503R	503	Missense	distal	4	no	6.630	6.631	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	4.810	Up-regulation
CAMK_CAMK2_CAMK2A_ST	Q14524	SCN5A	Q9UQM7	CAMK2A	S499	P495S	495	Missense	distal	-4	no	6.630	7.008	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	4.810	Up-regulation
CAMK_CAMK2_CAMK2A_ST	Q14524	SCN5A	Q9UQM7	CAMK2A	S499	D501N	501	Missense	proximal	2	no	6.630	5.619	EPSD;PhosphoSitePlus	TCGA;ICGC	4.810	Down-regulation
CAMK_CAMK2_CAMK2A_ST	Q14524	SCN5A	Q9UQM7	CAMK2A	S516	R523H	523	Missense	distal	7	no	7.724	7.676	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	4.810	Down-regulation
CAMK_CAMK2_CAMK2A_ST	Q14524	SCN5A	Q9UQM7	CAMK2A	S516	R513H	513	Missense	distal	-3	no	7.724	2.226	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	4.810	Loss
CAMK_CAMK2_CAMK2A_ST	Q14524	SCN5A	Q9UQM7	CAMK2A	S524	R523H	523	Missense	proximal	-1	no	5.646	5.792	EPSD	TCGA;ICGC;COSMIC	4.810	Up-regulation
CAMK_CAMK2_CAMK2A_ST	Q14524	SCN5A	Q9UQM7	CAMK2A	S571	R568C	568	Missense	distal	-3	no	6.593	1.012	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	4.810	Loss
CAMK_CAMK2_CAMK2A_ST	Q14524	SCN5A	Q9UQM7	CAMK2A	S571	G574E	574	Missense	distal	3	no	6.593	6.879	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	4.810	Up-regulation
CAMK_CAMK2_CAMK2A_ST	Q14524	SCN5A	Q9UQM7	CAMK2A	S571	P578L	578	Missense	distal	7	no	6.593	6.658	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	4.810	Up-regulation
CAMK_CAMK2_CAMK2A_ST	Q14524	SCN5A	Q9UQM7	CAMK2A	S581	A582D	582	Missense	proximal	1	no	4.885	4.673	EPSD	TCGA;ICGC;COSMIC	4.810	Loss
CAMK_CAMK2_CAMK2A_ST	Q14524	SCN5A	Q9UQM7	CAMK2A	S581	S581L	581	Missense	central	0	yes	4.885	0.000	EPSD	TCGA;ICGC;COSMIC;GDSC;CCLE	4.810	Loss
CAMK_CAMK2_CAMK2A_ST	Q14524	SCN5A	Q9UQM7	CAMK2A	S581	T580P	580	Missense	proximal	-1	no	4.885	4.860	EPSD	TCGA	4.810	Down-regulation
CAMK_CAMK2_CAMK2A_ST	Q14524	SCN5A	Q9UQM7	CAMK2A	S581	G584D	584	Missense	distal	3	no	4.885	5.049	EPSD	TCGA;ICGC;COSMIC	4.810	Up-regulation
CAMK_CAMK2_CAMK2A_ST	Q14524	SCN5A	Q9UQM7	CAMK2A	S581	G574E	574	Missense	distal	-7	no	4.885	4.597	EPSD	TCGA;ICGC;COSMIC	4.810	Loss
CAMK_CAMK2_CAMK2A_ST	Q14524	SCN5A	Q9UQM7	CAMK2A	S581	P578L	578	Missense	distal	-3	no	4.885	4.680	EPSD	TCGA;ICGC;COSMIC	4.810	Loss
CAMK_CAMK2_CAMK2A_ST	Q14524	SCN5A	Q9UQM7	CAMK2A	T594	V595G	595	Missense	proximal	1	no	7.816	7.184	EPSD	TCGA;ICGC;COSMIC	4.810	Down-regulation
CAMK_CAMK2_CAMK2A_ST	Q14524	SCN5A	Q9UQM7	CAMK2A	T594	C597S	597	Missense	distal	3	no	7.816	8.174	EPSD	TCGA;ICGC;COSMIC	4.810	Up-regulation
CAMK_CAMK2_CAMK2A_ST	Q14524	SCN5A	Q9UQM7	CAMK2A	T594	S593N	593	Missense	proximal	-1	no	7.816	7.681	EPSD	TCGA;ICGC;COSMIC;GDSC	4.810	Down-regulation
CAMK_CAMK2_CAMK2A_ST	Q14524	SCN5A	Q9UQM7	CAMK2A	S664	R661Q	661	Missense	distal	-3	no	7.191	3.619	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	4.810	Loss
CAMK_CAMK2_CAMK2A_ST	Q14524	SCN5A	Q9UQM7	CAMK2A	S664	R659W	659	Missense	distal	-5	no	7.191	7.339	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	4.810	Up-regulation
CAMK_CAMK2_CAMK2A_ST	Q14524	SCN5A	Q9UQM7	CAMK2A	S1503	P1509L	1509	Missense	distal	6	no	4.989	4.958	EPSD;PhosphoSitePlus	TCGA;COSMIC	4.810	Down-regulation
CAMK_CAMK2_CAMK2A_ST	Q14524	SCN5A	Q9UQM7	CAMK2A	S1503	K1500T	1500	Missense	distal	-3	no	4.989	2.201	EPSD;PhosphoSitePlus	TCGA;COSMIC	4.810	Loss
CAMK_CAMK2_CAMK2A_ST	Q14524	SCN5A	Q9UQM7	CAMK2A	S1925	A1932V	1932	Missense	distal	7	no	5.284	5.314	EPSD;PhosphoSitePlus	TCGA;COSMIC	4.810	Up-regulation
CAMK_CAMK2_CAMK2A_ST	Q14524	SCN5A	Q9UQM7	CAMK2A	S1925	R1929C	1929	Missense	distal	4	no	5.284	5.092	EPSD;PhosphoSitePlus	TCGA;COSMIC	4.810	Down-regulation
CAMK_CAMK2_CAMK2A_ST	Q14524	SCN5A	Q9UQM7	CAMK2A	S1925	R1919C	1919	Missense	distal	-6	no	5.284	5.479	EPSD;PhosphoSitePlus	TCGA;COSMIC	4.810	Up-regulation
CAMK_CAMK2_CAMK2A_ST	Q14524	SCN5A	Q9UQM7	CAMK2A	S1985	N1987S	1987	Missense	proximal	2	no	8.465	7.635	EPSD	TCGA	4.810	Down-regulation
CAMK_CAMK2_CAMK2A_ST	Q14524	SCN5A	Q9UQM7	CAMK2A	S1985	N1987I	1987	Missense	proximal	2	no	8.465	7.565	EPSD	TCGA;COSMIC	4.810	Down-regulation
CAMK_CAMK2_CAMK2A_ST	Q14524	SCN5A	Q9UQM7	CAMK2A	S1985	D1986N	1986	Missense	proximal	1	no	8.465	8.351	EPSD	TCGA;COSMIC	4.810	Down-regulation
CAMK_CAMK2_CAMK2A_ST	Q14524	SCN5A	Q9UQM7	CAMK2A	S1985	D1978H	1978	Missense	distal	-7	no	8.465	8.162	EPSD	TCGA;COSMIC;GDSC;CCLE	4.810	Down-regulation
CAMK_CAMK2_CAMK2A_ST	Q14524	SCN5A	Q9UQM7	CAMK2A	S1985	S1985G	1985	Missense	central	0	yes	8.465	0.000	EPSD	TCGA	4.810	Loss
CAMK_CAMK2_CAMK2A_ST	Q14524	SCN5A	Q9UQM7	CAMK2A	S1985	R1991W	1991	Missense	distal	6	no	8.465	8.227	EPSD	TCGA;COSMIC;GDSC;CCLE	4.810	Down-regulation
CAMK_CAMK2_CAMK2A_ST	Q14524	SCN5A	Q9UQM7	CAMK2A	S1985	R1991Q	1991	Missense	distal	6	no	8.465	8.471	EPSD	TCGA;COSMIC;GDSC;CCLE	4.810	Up-regulation
CAMK_CAMK2_CAMK2A_ST	P35367	HRH1	Q9UQM7	CAMK2A	T142	R143Q	143	Missense	proximal	1	no	6.650	6.623	PhosphoSitePlus;EPSD	TCGA;ICGC;COSMIC	4.810	Down-regulation
CAMK_CAMK2_CAMK2A_ST	P35367	HRH1	Q9UQM7	CAMK2A	T142	R139C	139	Missense	distal	-3	no	6.650	1.069	PhosphoSitePlus;EPSD	TCGA;ICGC;COSMIC	4.810	Loss
CAMK_CAMK2_CAMK2A_ST	P35367	HRH1	Q9UQM7	CAMK2A	T142	Y138S	138	Missense	distal	-4	no	6.650	6.974	PhosphoSitePlus;EPSD	TCGA;ICGC;COSMIC	4.810	Up-regulation
CAMK_CAMK2_CAMK2A_ST	P35367	HRH1	Q9UQM7	CAMK2A	T142	A146T	146	Missense	distal	4	no	6.650	6.612	PhosphoSitePlus;EPSD	TCGA;ICGC;COSMIC	4.810	Down-regulation
CAMK_CAMK2_CAMK2A_ST	P35367	HRH1	Q9UQM7	CAMK2A	S277	T279S	279	Missense	proximal	2	no	5.238	5.865	EPSD	TCGA;ICGC;COSMIC	4.810	Up-regulation
CAMK_CAMK2_CAMK2A_ST	P35367	HRH1	Q9UQM7	CAMK2A	S277	P276S	276	Missense	proximal	-1	no	5.238	5.424	EPSD	TCGA;ICGC;COSMIC	4.810	Up-regulation
CAMK_CAMK2_CAMK2A_ST	P35367	HRH1	Q9UQM7	CAMK2A	S277	P280S	280	Missense	distal	3	no	5.238	5.510	EPSD	TCGA;ICGC;COSMIC	4.810	Up-regulation
CAMK_CAMK2_CAMK2A_ST	P35367	HRH1	Q9UQM7	CAMK2A	S277	P280L	280	Missense	distal	3	no	5.238	5.197	EPSD	TCGA;ICGC;COSMIC	4.810	Down-regulation
CAMK_CAMK2_CAMK2A_ST	P35367	HRH1	Q9UQM7	CAMK2A	S363	S363L	363	Missense	central	0	yes	6.631	0.000	EPSD	TCGA;ICGC;COSMIC	4.810	Loss
CAMK_CAMK2_CAMK2A_ST	P35367	HRH1	Q9UQM7	CAMK2A	S363	S357F	357	Missense	distal	-6	no	6.631	6.747	EPSD	TCGA;ICGC;COSMIC	4.810	Up-regulation
CAMK_CAMK2_CAMK2A_ST	P35367	HRH1	Q9UQM7	CAMK2A	S378	R377S	377	Missense	proximal	-1	no	5.588	5.676	EPSD	TCGA;ICGC;COSMIC	4.810	Up-regulation
CAMK_CAMK2_CAMK2A_ST	P35367	HRH1	Q9UQM7	CAMK2A	S378	R377K	377	Missense	proximal	-1	no	5.588	5.738	EPSD	TCGA;ICGC;COSMIC	4.810	Up-regulation
CAMK_CAMK2_CAMK2A_ST	P35367	HRH1	Q9UQM7	CAMK2A	S380	R377S	377	Missense	distal	-3	no	6.421	1.961	EPSD	TCGA;ICGC;COSMIC	4.810	Loss
CAMK_CAMK2_CAMK2A_ST	P35367	HRH1	Q9UQM7	CAMK2A	S380	R377K	377	Missense	distal	-3	no	6.421	4.153	EPSD	TCGA;ICGC;COSMIC	4.810	Loss
CAMK_CAMK2_CAMK2A_ST	P35367	HRH1	Q9UQM7	CAMK2A	S396	S396L	396	Missense	central	0	yes	7.356	0.000	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	4.810	Loss
CAMK_CAMK2_CAMK2A_ST	P35367	HRH1	Q9UQM7	CAMK2A	S396	R395H	395	Missense	proximal	-1	no	7.356	7.501	EPSD;PhosphoSitePlus	TCGA;ICGC	4.810	Up-regulation
CAMK_CAMK2_CAMK2A_ST	P35367	HRH1	Q9UQM7	CAMK2A	S398	S396L	396	Missense	proximal	-2	no	9.364	9.262	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	4.810	Down-regulation
CAMK_CAMK2_CAMK2A_ST	P35367	HRH1	Q9UQM7	CAMK2A	S398	R395H	395	Missense	distal	-3	no	9.364	3.867	EPSD;PhosphoSitePlus	TCGA;ICGC	4.810	Loss
CAMK_CAMK2_CAMK2A_ST	P15036	ETS2	Q9UQM7	CAMK2A	S246	V249I	249	Missense	distal	3	no	8.446	8.222	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	4.810	Down-regulation
CAMK_CAMK2_CAMK2A_ST	P15036	ETS2	Q9UQM7	CAMK2A	S246	S242F	242	Missense	distal	-4	no	8.446	7.928	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	4.810	Down-regulation
CAMK_CAMK2_CAMK2A_ST	P15036	ETS2	Q9UQM7	CAMK2A	S310	P309S	309	Missense	proximal	-1	no	6.673	6.859	PhosphoSitePlus;EPSD	TCGA;ICGC;COSMIC	4.810	Up-regulation
CAMK_CAMK2_CAMK2A_ST	P15036	ETS2	Q9UQM7	CAMK2A	S313	P309S	309	Missense	distal	-4	no	4.578	4.956	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	4.810	Gain
CAMK_CAMK2_CAMK2A_ST	P23677	ITPKA	Q9UQM7	CAMK2A	S121	L114P	114	Missense	distal	-7	no	7.069	7.103	EPSD	TCGA;ICGC;COSMIC	4.810	Up-regulation
CAMK_CAMK2_CAMK2A_ST	P23677	ITPKA	Q9UQM7	CAMK2A	T311	V310I	310	Missense	proximal	-1	no	6.144	6.139	PhosphoSitePlus	TCGA;ICGC;COSMIC	4.810	Down-regulation
CAMK_CAMK2_CAMK2A_ST	P23677	ITPKA	Q9UQM7	CAMK2A	T311	P313L	313	Missense	proximal	2	no	6.144	6.308	PhosphoSitePlus	TCGA;ICGC	4.810	Up-regulation
CAMK_CAMK2_CAMK2A_ST	P23677	ITPKA	Q9UQM7	CAMK2A	T311	T311A	311	Missense	central	0	yes	6.144	0.000	PhosphoSitePlus	TCGA;ICGC;COSMIC	4.810	Loss
CAMK_CAMK2_CAMK2A_ST	Q9Y618	NCOR2	Q9UQM7	CAMK2A	S132	D138Y	138	Missense	distal	6	no	4.822	4.684	EPSD	TCGA;ICGC;COSMIC	4.810	Loss
CAMK_CAMK2_CAMK2A_ST	Q9Y618	NCOR2	Q9UQM7	CAMK2A	S132	G131V	131	Missense	proximal	-1	no	4.822	4.798	EPSD	TCGA;ICGC;COSMIC	4.810	Loss
CAMK_CAMK2_CAMK2A_ST	Q9Y618	NCOR2	Q9UQM7	CAMK2A	S140	D138Y	138	Missense	proximal	-2	no	5.987	6.193	EPSD	TCGA;ICGC;COSMIC	4.810	Up-regulation
CAMK_CAMK2_CAMK2A_ST	Q9Y618	NCOR2	Q9UQM7	CAMK2A	S225	R224H	224	Missense	proximal	-1	no	5.925	6.071	EPSD	TCGA;ICGC;COSMIC	4.810	Up-regulation
CAMK_CAMK2_CAMK2A_ST	Q9Y618	NCOR2	Q9UQM7	CAMK2A	S225	D232E	232	Missense	distal	7	no	5.925	5.717	EPSD	TCGA;ICGC;COSMIC	4.810	Down-regulation
CAMK_CAMK2_CAMK2A_ST	Q9Y618	NCOR2	Q9UQM7	CAMK2A	S225	E220K	220	Missense	distal	-5	no	5.925	5.922	EPSD	TCGA;ICGC;COSMIC	4.810	Down-regulation
CAMK_CAMK2_CAMK2A_ST	Q9Y618	NCOR2	Q9UQM7	CAMK2A	S493	R488Q	488	Missense	distal	-5	no	6.613	6.516	EPSD	TCGA;COSMIC	4.810	Down-regulation
CAMK_CAMK2_CAMK2A_ST	Q9Y618	NCOR2	Q9UQM7	CAMK2A	T550	S554L	554	Missense	distal	4	no	5.344	5.134	EPSD	TCGA;COSMIC	4.810	Down-regulation
CAMK_CAMK2_CAMK2A_ST	Q9Y618	NCOR2	Q9UQM7	CAMK2A	S753	H755D	755	Missense	proximal	2	no	3.529	6.014	EPSD	TCGA;COSMIC	4.810	Gain
CAMK_CAMK2_CAMK2A_ST	Q9Y618	NCOR2	Q9UQM7	CAMK2A	T867	S864R	864	Missense	distal	-3	no	4.164	8.624	EPSD	TCGA;COSMIC	4.810	Gain
CAMK_CAMK2_CAMK2A_ST	Q9Y618	NCOR2	Q9UQM7	CAMK2A	S922	D924G	924	Missense	proximal	2	no	5.928	4.093	EPSD	TCGA;COSMIC	4.810	Loss
CAMK_CAMK2_CAMK2A_ST	Q9Y618	NCOR2	Q9UQM7	CAMK2A	S922	S917F	917	Missense	distal	-5	no	5.928	5.946	EPSD	TCGA	4.810	Up-regulation
CAMK_CAMK2_CAMK2A_ST	Q9Y618	NCOR2	Q9UQM7	CAMK2A	S939	R936W	936	Missense	distal	-3	no	7.929	-4.091	EPSD	TCGA;COSMIC	4.810	Loss
CAMK_CAMK2_CAMK2A_ST	Q9Y618	NCOR2	Q9UQM7	CAMK2A	S939	R936L	936	Missense	distal	-3	no	7.929	2.807	EPSD	TCGA;COSMIC	4.810	Loss
CAMK_CAMK2_CAMK2A_ST	Q9Y618	NCOR2	Q9UQM7	CAMK2A	S1017	R1020Q	1020	Missense	distal	3	no	4.945	4.968	EPSD	TCGA;COSMIC	4.810	Up-regulation
CAMK_CAMK2_CAMK2A_ST	Q9Y618	NCOR2	Q9UQM7	CAMK2A	S1023	A1030T	1030	Missense	distal	7	no	7.889	7.938	EPSD	TCGA;COSMIC	4.810	Up-regulation
CAMK_CAMK2_CAMK2A_ST	Q9Y618	NCOR2	Q9UQM7	CAMK2A	S1023	R1020Q	1020	Missense	distal	-3	no	7.889	4.318	EPSD	TCGA;COSMIC	4.810	Loss
CAMK_CAMK2_CAMK2A_ST	Q9Y618	NCOR2	Q9UQM7	CAMK2A	S1025	A1030T	1030	Missense	distal	5	no	5.954	5.741	EPSD	TCGA;COSMIC	4.810	Down-regulation
CAMK_CAMK2_CAMK2A_ST	Q9Y618	NCOR2	Q9UQM7	CAMK2A	S1025	D1031N	1031	Missense	distal	6	no	5.954	5.922	EPSD	TCGA;COSMIC	4.810	Down-regulation
CAMK_CAMK2_CAMK2A_ST	Q9Y618	NCOR2	Q9UQM7	CAMK2A	S1025	K1032N	1032	Missense	distal	7	no	5.954	5.933	EPSD	TCGA;COSMIC	4.810	Down-regulation
CAMK_CAMK2_CAMK2A_ST	Q9Y618	NCOR2	Q9UQM7	CAMK2A	S1025	R1020Q	1020	Missense	distal	-5	no	5.954	5.857	EPSD	TCGA;COSMIC	4.810	Down-regulation
CAMK_CAMK2_CAMK2A_ST	Q9Y618	NCOR2	Q9UQM7	CAMK2A	S1588	S1595F	1595	Missense	distal	7	no	4.693	4.939	EPSD	TCGA;COSMIC	4.810	Gain
CAMK_CAMK2_CAMK2A_ST	Q9Y618	NCOR2	Q9UQM7	CAMK2A	T1594	S1595F	1595	Missense	proximal	1	no	5.024	5.209	EPSD	TCGA;COSMIC	4.810	Up-regulation
CAMK_CAMK2_CAMK2A_ST	Q9Y618	NCOR2	Q9UQM7	CAMK2A	S1595	S1595F	1595	Missense	central	0	yes	5.284	0.000	EPSD	TCGA;COSMIC	4.810	Loss
CAMK_CAMK2_CAMK2A_ST	Q9Y618	NCOR2	Q9UQM7	CAMK2A	S1782	L1785F	1785	Missense	distal	3	no	7.652	7.586	EPSD	TCGA;COSMIC	4.810	Down-regulation
CAMK_CAMK2_CAMK2A_ST	Q9Y618	NCOR2	Q9UQM7	CAMK2A	S1861	P1859L	1859	Missense	proximal	-2	no	8.372	8.262	EPSD	TCGA;COSMIC	4.810	Down-regulation
CAMK_CAMK2_CAMK2A_ST	Q9Y618	NCOR2	Q9UQM7	CAMK2A	S1861	S1861F	1861	Missense	central	0	yes	8.372	0.000	EPSD	TCGA;COSMIC	4.810	Loss
CAMK_CAMK2_CAMK2A_ST	Q9Y618	NCOR2	Q9UQM7	CAMK2A	S2025	E2032Q	2032	Missense	distal	7	no	5.266	5.395	EPSD	TCGA;COSMIC	4.810	Up-regulation
CAMK_CAMK2_CAMK2A_ST	Q14654	KCNJ11	Q9UQM7	CAMK2A	T180	R176C	176	Missense	distal	-4	no	7.115	6.481	PhosphoSitePlus;EPSD	TCGA;ICGC;COSMIC	4.810	Down-regulation
CAMK_CAMK2_CAMK2A_ST	Q14654	KCNJ11	Q9UQM7	CAMK2A	T224	Q218H	218	Missense	distal	-6	no	5.257	5.207	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	4.810	Down-regulation
CAMK_CAMK2_CAMK2A_ST	Q14654	KCNJ11	Q9UQM7	CAMK2A	T224	S225N	225	Missense	proximal	1	no	5.257	4.714	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	4.810	Loss
CAMK_CAMK2_CAMK2A_ST	Q14654	KCNJ11	Q9UQM7	CAMK2A	S372	M375V	375	Missense	distal	3	no	9.838	9.997	EPSD	TCGA;ICGC;COSMIC	4.810	Up-regulation
CAMK_CAMK2_CAMK2A_ST	Q14654	KCNJ11	Q9UQM7	CAMK2A	S372	R371C	371	Missense	proximal	-1	no	9.838	9.509	EPSD	TCGA;ICGC;COSMIC	4.810	Down-regulation
CAMK_CAMK2_CAMK2A_ST	Q96PH1	NOX5	Q9UQM7	CAMK2A	S521	R517M	517	Missense	distal	-4	no	4.996	4.839	EPSD	TCGA;ICGC	4.810	Down-regulation
CAMK_CAMK2_CAMK2A_ST	Q96PH1	NOX5	Q9UQM7	CAMK2A	T540	R542T	542	Missense	proximal	2	no	7.516	6.465	EPSD	TCGA;COSMIC	4.810	Down-regulation
CAMK_CAMK2_CAMK2A_ST	Q96PH1	NOX5	Q9UQM7	CAMK2A	T540	K543N	543	Missense	distal	3	no	7.516	7.431	EPSD	TCGA;ICGC;COSMIC	4.810	Down-regulation
CAMK_CAMK2_CAMK2A_ST	Q96PH1	NOX5	Q9UQM7	CAMK2A	S705	T707M	707	Missense	proximal	2	no	5.518	6.243	EPSD	TCGA;COSMIC	4.810	Up-regulation
CAMK_CAMK2_CAMK2A_ST	Q96PH1	NOX5	Q9UQM7	CAMK2A	S705	R712C	712	Missense	distal	7	no	5.518	5.674	EPSD	TCGA;COSMIC	4.810	Up-regulation
CAMK_CAMK2_CAMK2A_ST	P05556	ITGB1	Q9UQM7	CAMK2A	S125	S125L	125	Missense	central	0	yes	6.922	0.000	EPSD	TCGA;ICGC;COSMIC	4.810	Loss
CAMK_CAMK2_CAMK2A_ST	P05556	ITGB1	Q9UQM7	CAMK2A	S178	I182L	182	Missense	distal	4	no	5.881	5.936	EPSD	TCGA;ICGC;COSMIC	4.810	Up-regulation
CAMK_CAMK2_CAMK2A_ST	P05556	ITGB1	Q9UQM7	CAMK2A	S197	P194R	194	Missense	distal	-3	no	1.534	6.452	EPSD	TCGA;ICGC;COSMIC	4.810	Gain
CAMK_CAMK2_CAMK2A_ST	P05556	ITGB1	Q9UQM7	CAMK2A	S549	E546K	546	Missense	distal	-3	no	2.701	5.552	EPSD	TCGA;ICGC;COSMIC	4.810	Gain
CAMK_CAMK2_CAMK2A_ST	P05556	ITGB1	Q9UQM7	CAMK2A	S593	E600K	600	Missense	distal	7	no	5.295	5.505	EPSD	TCGA;ICGC;COSMIC	4.810	Up-regulation
CAMK_CAMK2_CAMK2A_ST	P05556	ITGB1	Q9UQM7	CAMK2A	S597	E600K	600	Missense	distal	3	no	4.862	4.697	EPSD	TCGA;ICGC;COSMIC	4.810	Loss
CAMK_CAMK2_CAMK2A_ST	P07101	TH	Q9UQM7	CAMK2A	S19	A23T	23	Missense	distal	4	no	10.486	10.448	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	4.810	Down-regulation
CAMK_CAMK2_CAMK2A_ST	P07101	TH	Q9UQM7	CAMK2A	S19	R15H	15	Missense	distal	-4	no	10.486	10.363	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC;GDSC	4.810	Down-regulation
CAMK_CAMK2_CAMK2A_ST	P07101	TH	Q9UQM7	CAMK2A	S71	R64W	64	Missense	distal	-7	no	9.735	10.479	EPSD;PhosphoSitePlus	TCGA;COSMIC	4.810	Up-regulation
CAMK_CAMK2_CAMK2A_ST	P07101	TH	Q9UQM7	CAMK2A	S71	K78N	78	Missense	distal	7	no	9.735	9.715	EPSD;PhosphoSitePlus	TCGA;COSMIC	4.810	Down-regulation
CAMK_CAMK2_CAMK2A_ST	O15273	TCAP	Q9UQM7	CAMK2A	T109	E107D	107	Missense	proximal	-2	no	5.609	5.303	EPSD	TCGA	4.810	Down-regulation
CAMK_CAMK2_CAMK2A_ST	O15273	TCAP	Q9UQM7	CAMK2A	T109	T109I	109	Missense	central	0	yes	5.609	0.000	EPSD	TCGA;COSMIC	4.810	Loss
CAMK_CAMK2_CAMK2A_ST	O15273	TCAP	Q9UQM7	CAMK2A	T109	L116M	116	Missense	distal	7	no	5.609	5.548	EPSD	TCGA	4.810	Down-regulation
CAMK_CAMK2_CAMK2A_ST	O15273	TCAP	Q9UQM7	CAMK2A	S157	S159F	159	Missense	proximal	2	no	9.266	8.015	PhosphoSitePlus;EPSD	TCGA;COSMIC	4.810	Down-regulation
CAMK_CAMK2_CAMK2A_ST	O15273	TCAP	Q9UQM7	CAMK2A	S157	R154C	154	Missense	distal	-3	no	9.266	3.685	PhosphoSitePlus;EPSD	TCGA;COSMIC	4.810	Loss
CAMK_CAMK2_CAMK2A_ST	O15273	TCAP	Q9UQM7	CAMK2A	S157	S155P	155	Missense	proximal	-2	no	9.266	9.273	PhosphoSitePlus;EPSD	TCGA;COSMIC	4.810	Up-regulation
CAMK_CAMK2_CAMK2A_ST	O15273	TCAP	Q9UQM7	CAMK2A	S157	M160T	160	Missense	distal	3	no	9.266	9.252	PhosphoSitePlus;EPSD	TCGA;COSMIC	4.810	Down-regulation
CAMK_CAMK2_CAMK2A_ST	O15273	TCAP	Q9UQM7	CAMK2A	S159	S159F	159	Missense	central	0	yes	4.874	0.000	EPSD	TCGA;COSMIC	4.810	Loss
CAMK_CAMK2_CAMK2A_ST	O15273	TCAP	Q9UQM7	CAMK2A	S159	R154C	154	Missense	distal	-5	no	4.874	4.872	EPSD	TCGA;COSMIC	4.810	Down-regulation
CAMK_CAMK2_CAMK2A_ST	O15273	TCAP	Q9UQM7	CAMK2A	S159	S155P	155	Missense	distal	-4	no	4.874	4.495	EPSD	TCGA;COSMIC	4.810	Loss
CAMK_CAMK2_CAMK2A_ST	O15273	TCAP	Q9UQM7	CAMK2A	S159	M160T	160	Missense	proximal	1	no	4.874	4.511	EPSD	TCGA;COSMIC	4.810	Loss
CAMK_CAMK2_CAMK2A_ST	O15273	TCAP	Q9UQM7	CAMK2A	S161	S159F	159	Missense	proximal	-2	no	10.543	9.758	EPSD;PhosphoSitePlus	TCGA;COSMIC	4.810	Down-regulation
CAMK_CAMK2_CAMK2A_ST	O15273	TCAP	Q9UQM7	CAMK2A	S161	R154C	154	Missense	distal	-7	no	10.543	11.212	EPSD;PhosphoSitePlus	TCGA;COSMIC	4.810	Up-regulation
CAMK_CAMK2_CAMK2A_ST	O15273	TCAP	Q9UQM7	CAMK2A	S161	S155P	155	Missense	distal	-6	no	10.543	10.592	EPSD;PhosphoSitePlus	TCGA;COSMIC	4.810	Up-regulation
CAMK_CAMK2_CAMK2A_ST	O15273	TCAP	Q9UQM7	CAMK2A	S161	M160T	160	Missense	proximal	-1	no	10.543	10.390	EPSD;PhosphoSitePlus	TCGA;COSMIC	4.810	Down-regulation
CAMK_CAMK2_CAMK2A_ST	Q9UQM7	CAMK2A	Q9UQM7	CAMK2A	T286	V287M	287	Missense	proximal	1	no	9.916	10.027	PhosphoSitePlus;EPSD	TCGA;ICGC;COSMIC	4.810	Up-regulation
CAMK_CAMK2_CAMK2A_ST	Q9UQM7	CAMK2A	Q9UQM7	CAMK2A	T306	L304V	304	Missense	proximal	-2	no	5.354	5.147	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	4.810	Down-regulation
CAMK_CAMK2_CAMK2A_ST	Q9UQM7	CAMK2A	Q9UQM7	CAMK2A	T306	F313L	313	Missense	distal	7	no	5.354	5.272	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	4.810	Down-regulation
CAMK_CAMK2_CAMK2A_ST	Q9UQM7	CAMK2A	Q9UQM7	CAMK2A	S314	F313L	313	Missense	proximal	-1	no	7.135	7.266	EPSD	TCGA;ICGC;COSMIC	4.810	Up-regulation
CAMK_CAMK2_CAMK2A_ST	Q9UQM7	CAMK2A	Q9UQM7	CAMK2A	S331	D325N	325	Missense	distal	-6	no	6.517	6.539	EPSD	TCGA;ICGC;COSMIC	4.810	Up-regulation
CAMK_CAMK2_CAMK2A_ST	P28329	CHAT	Q9UQM7	CAMK2A	S125	S126R	126	Missense	proximal	1	no	6.995	6.808	EPSD	TCGA;COSMIC	4.810	Down-regulation
CAMK_CAMK2_CAMK2A_ST	P28329	CHAT	Q9UQM7	CAMK2A	S125	E128Q	128	Missense	distal	3	no	6.995	6.787	EPSD	TCGA;COSMIC	4.810	Down-regulation
CAMK_CAMK2_CAMK2A_ST	P28329	CHAT	Q9UQM7	CAMK2A	S125	G130R	130	Missense	distal	5	no	6.995	7.038	EPSD	TCGA;COSMIC	4.810	Up-regulation
CAMK_CAMK2_CAMK2A_ST	P28329	CHAT	Q9UQM7	CAMK2A	S125	G130E	130	Missense	distal	5	no	6.995	7.117	EPSD	TCGA;COSMIC	4.810	Up-regulation
CAMK_CAMK2_CAMK2A_ST	P28329	CHAT	Q9UQM7	CAMK2A	S125	A121V	121	Missense	distal	-4	no	6.995	6.706	EPSD	TCGA;COSMIC	4.810	Down-regulation
CAMK_CAMK2_CAMK2A_ST	P28329	CHAT	Q9UQM7	CAMK2A	S125	T123N	123	Missense	proximal	-2	no	6.995	7.187	EPSD	TCGA	4.810	Up-regulation
CAMK_CAMK2_CAMK2A_ST	P28329	CHAT	Q9UQM7	CAMK2A	S473	V474I	474	Missense	proximal	1	no	8.060	8.268	EPSD	TCGA;COSMIC;CCLE	4.810	Up-regulation
CAMK_CAMK2_CAMK2A_ST	P28329	CHAT	Q9UQM7	CAMK2A	S473	S473Y	473	Missense	central	0	yes	8.060	0.000	EPSD	TCGA;COSMIC	4.810	Loss
CAMK_CAMK2_CAMK2A_ST	P28329	CHAT	Q9UQM7	CAMK2A	S473	P478R	478	Missense	distal	5	no	8.060	8.149	EPSD	TCGA;COSMIC	4.810	Up-regulation
CAMK_CAMK2_CAMK2A_ST	P28329	CHAT	Q9UQM7	CAMK2A	S473	P478H	478	Missense	distal	5	no	8.060	8.263	EPSD	TCGA;COSMIC	4.810	Up-regulation
CAMK_CAMK2_CAMK2A_ST	P28329	CHAT	Q9UQM7	CAMK2A	S473	R470Q	470	Missense	distal	-3	no	8.060	4.489	EPSD	TCGA;COSMIC	4.810	Loss
CAMK_CAMK2_CAMK2A_ST	P28329	CHAT	Q9UQM7	CAMK2A	S473	R466K	466	Missense	distal	-7	no	8.060	7.995	EPSD	TCGA;COSMIC	4.810	Down-regulation
CAMK_CAMK2_CAMK2A_ST	P28329	CHAT	Q9UQM7	CAMK2A	S473	E476K	476	Missense	distal	3	no	8.060	7.895	EPSD	TCGA;COSMIC	4.810	Down-regulation
CAMK_CAMK2_CAMK2A_ST	P28329	CHAT	Q9UQM7	CAMK2A	T574	S572L	572	Missense	proximal	-2	no	5.843	5.740	EPSD	TCGA;COSMIC;CCLE	4.810	Down-regulation
CAMK_CAMK2_CAMK2A_ST	P28329	CHAT	Q9UQM7	CAMK2A	T574	R571I	571	Missense	distal	-3	no	5.843	1.572	EPSD	TCGA;COSMIC	4.810	Loss
CAMK_CAMK2_CAMK2A_ST	P14921	ETS1	Q9UQM7	CAMK2A	S254	S251L	251	Missense	distal	-3	no	6.034	5.372	EPSD	TCGA;ICGC;COSMIC	4.810	Down-regulation
CAMK_CAMK2_CAMK2A_ST	P14921	ETS1	Q9UQM7	CAMK2A	S257	S251L	251	Missense	distal	-6	no	5.093	5.147	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	4.810	Up-regulation
CAMK_CAMK2_CAMK2A_ST	P35270	SPR	Q9UQM7	CAMK2A	S35	A28T	28	Missense	distal	-7	no	4.972	5.313	EPSD	TCGA;ICGC;COSMIC	4.810	Up-regulation
CAMK_CAMK2_CAMK2A_ST	P35270	SPR	Q9UQM7	CAMK2A	S213	S213Y	213	Missense	central	0	yes	9.050	0.000	PhosphoSitePlus	TCGA;ICGC;COSMIC	4.810	Loss
CAMK_CAMK2_CAMK2A_ST	P35270	SPR	Q9UQM7	CAMK2A	S213	T212I	212	Missense	proximal	-1	no	9.050	9.037	PhosphoSitePlus	TCGA;ICGC;COSMIC	4.810	Down-regulation
CAMK_CAMK2_CAMK2A_ST	P35270	SPR	Q9UQM7	CAMK2A	S243	E249K	249	Missense	distal	6	no	6.278	6.227	EPSD	TCGA;ICGC;COSMIC	4.810	Down-regulation
CAMK_CAMK2_CAMK2A_ST	P35270	SPR	Q9UQM7	CAMK2A	S243	F250L	250	Missense	distal	7	no	6.278	6.196	EPSD	TCGA;ICGC;COSMIC	4.810	Down-regulation
CAMK_CAMK2_CAMK2A_ST	P43003	SLC1A3	Q9UQM7	CAMK2A	T26	G21E	21	Missense	distal	-5	no	7.224	7.076	PhosphoSitePlus;EPSD	TCGA;ICGC;COSMIC	4.810	Down-regulation
CAMK_CAMK2_CAMK2A_ST	P43003	SLC1A3	Q9UQM7	CAMK2A	T26	K31N	31	Missense	distal	5	no	7.224	7.144	PhosphoSitePlus;EPSD	TCGA;ICGC;COSMIC	4.810	Down-regulation
CAMK_CAMK2_CAMK2A_ST	O95997	PTTG1	Q9UQM7	CAMK2A	S183	S176C	176	Missense	distal	-7	no	4.391	5.027	EPSD	TCGA;ICGC;COSMIC	4.810	Gain
CAMK_CAMK2_CAMK2A_ST	O95997	PTTG1	Q9UQM7	CAMK2A	S187	S187L	187	Missense	central	0	yes	6.183	0.000	EPSD	TCGA;ICGC;COSMIC	4.810	Loss
CAMK_CAMK2_CAMK2A_ST	Q15796	SMAD2	Q9UQM7	CAMK2A	S260	Q264L	264	Missense	distal	4	no	5.329	5.121	PhosphoSitePlus;EPSD	TCGA;ICGC;COSMIC	4.810	Down-regulation
CAMK_CAMK2_CAMK2A_ST	Q15796	SMAD2	Q9UQM7	CAMK2A	S260	D262Y	262	Missense	proximal	2	no	5.329	1.752	PhosphoSitePlus;EPSD	TCGA;ICGC;COSMIC	4.810	Loss
CAMK_CAMK2_CAMK2A_ST	Q15796	SMAD2	Q9UQM7	CAMK2A	T324	R321Q	321	Missense	distal	-3	no	5.120	1.548	EPSD	TCGA;ICGC;COSMIC;GDSC;CCLE	4.810	Loss
CAMK_CAMK2_CAMK2A_ST	Q15796	SMAD2	Q9UQM7	CAMK2A	T324	M327I	327	Missense	distal	3	no	5.120	5.056	EPSD	TCGA;ICGC;COSMIC	4.810	Down-regulation
CAMK_CAMK2_CAMK2A_ST	Q15796	SMAD2	Q9UQM7	CAMK2A	T324	R330M	330	Missense	distal	6	no	5.120	5.080	EPSD	TCGA;ICGC	4.810	Down-regulation
CAMK_CAMK2_CAMK2A_ST	Q15796	SMAD2	Q9UQM7	CAMK2A	T324	E326A	326	Missense	proximal	2	no	5.120	4.235	EPSD	TCGA;ICGC;COSMIC	4.810	Loss
CAMK_CAMK2_CAMK2A_ST	Q15796	SMAD2	Q9UQM7	CAMK2A	T324	A323V	323	Missense	proximal	-1	no	5.120	4.896	EPSD	TCGA;ICGC;COSMIC	4.810	Down-regulation
CAMK_CAMK2_CAMK2A_ST	Q15796	SMAD2	Q9UQM7	CAMK2A	T430	R428K	428	Missense	proximal	-2	no	6.049	6.225	EPSD	TCGA;ICGC;COSMIC	4.810	Up-regulation
CAMK_CAMK2_CAMK2A_ST	Q15796	SMAD2	Q9UQM7	CAMK2A	T430	S433G	433	Missense	distal	3	no	6.049	5.898	EPSD	TCGA;ICGC;COSMIC	4.810	Down-regulation
CAMK_CAMK2_CAMK2A_ST	P46527	CDKN1B	Q9UQM7	CAMK2A	S12	S7C	7	Missense	distal	-5	no	4.883	4.811	EPSD	TCGA;ICGC;COSMIC	4.810	Down-regulation
CAMK_CAMK2_CAMK2A_ST	P46527	CDKN1B	Q9UQM7	CAMK2A	S12	G9W	9	Missense	distal	-3	no	4.883	-2.539	EPSD	TCGA;ICGC;COSMIC	4.810	Loss
CAMK_CAMK2_CAMK2A_ST	P46527	CDKN1B	Q9UQM7	CAMK2A	S106	A103V	103	Missense	distal	-3	no	5.959	5.257	EPSD	TCGA;ICGC	4.810	Down-regulation
CAMK_CAMK2_CAMK2A_ST	P46527	CDKN1B	Q9UQM7	CAMK2A	T157	S161C	161	Missense	distal	4	no	8.037	7.673	EPSD	TCGA;ICGC;COSMIC	4.810	Down-regulation
CAMK_CAMK2_CAMK2A_ST	P46527	CDKN1B	Q9UQM7	CAMK2A	T157	S161Y	161	Missense	distal	4	no	8.037	7.953	EPSD	TCGA;ICGC	4.810	Down-regulation
CAMK_CAMK2_CAMK2A_ST	P46527	CDKN1B	Q9UQM7	CAMK2A	T157	G150E	150	Missense	distal	-7	no	8.037	7.749	EPSD	TCGA;ICGC;COSMIC	4.810	Down-regulation
CAMK_CAMK2_CAMK2A_ST	Q9NQC7	CYLD	Q9UQM7	CAMK2A	S352	G347E	347	Missense	distal	-5	no	6.913	6.765	EPSD	TCGA;ICGC;COSMIC	4.810	Down-regulation
CAMK_CAMK2_CAMK2A_ST	Q9NQC7	CYLD	Q9UQM7	CAMK2A	S361	G360V	360	Missense	proximal	-1	no	4.844	4.820	EPSD	TCGA;ICGC;COSMIC	4.810	Down-regulation
CAMK_CAMK2_CAMK2A_ST	Q9NQC7	CYLD	Q9UQM7	CAMK2A	S362	G360V	360	Missense	proximal	-2	no	5.998	5.846	PhosphoSitePlus;EPSD	TCGA;ICGC;COSMIC	4.810	Down-regulation
CAMK_CAMK2_CAMK2A_ST	Q9NQC7	CYLD	Q9UQM7	CAMK2A	S418	N414H	414	Missense	distal	-4	no	5.712	5.682	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	4.810	Down-regulation
CAMK_CAMK2_CAMK2A_ST	Q9NQC7	CYLD	Q9UQM7	CAMK2A	S418	E413D	413	Missense	distal	-5	no	5.712	5.876	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	4.810	Up-regulation
CAMK_CAMK2_CAMK2A_ST	Q9NQC7	CYLD	Q9UQM7	CAMK2A	S418	K425E	425	Missense	distal	7	no	5.712	5.502	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	4.810	Down-regulation
CAMK_CAMK2_CAMK2A_ST	Q9NQC7	CYLD	Q9UQM7	CAMK2A	S444	E447D	447	Missense	distal	3	no	5.317	5.194	EPSD	TCGA;ICGC;COSMIC	4.810	Down-regulation
CAMK_CAMK2_CAMK2A_ST	Q9NQC7	CYLD	Q9UQM7	CAMK2A	S547	R540M	540	Missense	distal	-7	no	6.832	6.837	EPSD	TCGA;ICGC;COSMIC	4.810	Up-regulation
CAMK_CAMK2_CAMK2A_ST	Q9NQC7	CYLD	Q9UQM7	CAMK2A	S560	R557H	557	Missense	distal	-3	no	8.079	2.582	EPSD	TCGA;ICGC;COSMIC	4.810	Loss
CAMK_CAMK2_CAMK2A_ST	Q9NQC7	CYLD	Q9UQM7	CAMK2A	S560	A562V	562	Missense	proximal	2	no	8.079	8.065	EPSD	TCGA;ICGC;COSMIC	4.810	Down-regulation
CAMK_CAMK2_CAMK2A_ST	Q9NQC7	CYLD	Q9UQM7	CAMK2A	S772	I769F	769	Missense	distal	-3	no	5.259	-4.017	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	4.810	Loss
CAMK_CAMK2_CAMK2A_ST	Q9NQC7	CYLD	Q9UQM7	CAMK2A	S772	D779Y	779	Missense	distal	7	no	5.259	5.369	EPSD;PhosphoSitePlus	TCGA;ICGC	4.810	Up-regulation
CAMK_CAMK2_CAMK2A_ST	Q9NQC7	CYLD	Q9UQM7	CAMK2A	S772	T778K	778	Missense	distal	6	no	5.259	5.275	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	4.810	Up-regulation
CAMK_CAMK2_CAMK2A_ST	Q9NQC7	CYLD	Q9UQM7	CAMK2A	S772	D779N	779	Missense	distal	7	no	5.259	5.241	EPSD;PhosphoSitePlus	TCGA;ICGC	4.810	Down-regulation
CAMK_CAMK2_CAMK2A_ST	Q9NQC7	CYLD	Q9UQM7	CAMK2A	S772	F766L	766	Missense	distal	-6	no	5.259	5.199	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	4.810	Down-regulation
CAMK_CAMK2_CAMK2A_ST	Q9NQC7	CYLD	Q9UQM7	CAMK2A	S772	I769N	769	Missense	distal	-3	no	5.259	4.697	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	4.810	Loss
CAMK_CAMK2_CAMK2A_ST	Q92736	RYR2	Q9UQM7	CAMK2A	S307	S307C	307	Missense	central	0	yes	6.019	0.000	EPSD	TCGA;COSMIC	4.810	Loss
CAMK_CAMK2_CAMK2A_ST	Q92736	RYR2	Q9UQM7	CAMK2A	S307	N313I	313	Missense	distal	6	no	6.019	5.930	EPSD	TCGA;COSMIC	4.810	Down-regulation
CAMK_CAMK2_CAMK2A_ST	Q92736	RYR2	Q9UQM7	CAMK2A	S307	Y305N	305	Missense	proximal	-2	no	6.019	6.244	EPSD	TCGA;COSMIC	4.810	Up-regulation
CAMK_CAMK2_CAMK2A_ST	Q92736	RYR2	Q9UQM7	CAMK2A	S307	T302R	302	Missense	distal	-5	no	6.019	5.951	EPSD	TCGA;COSMIC	4.810	Down-regulation
CAMK_CAMK2_CAMK2A_ST	Q92736	RYR2	Q9UQM7	CAMK2A	S856	P853R	853	Missense	distal	-3	no	2.730	7.648	EPSD	TCGA;COSMIC	4.810	Gain
CAMK_CAMK2_CAMK2A_ST	Q92736	RYR2	Q9UQM7	CAMK2A	S2031	R2028H	2028	Missense	distal	-3	no	6.199	0.702	EPSD	TCGA;COSMIC;CCLE	4.810	Loss
CAMK_CAMK2_CAMK2A_ST	Q92736	RYR2	Q9UQM7	CAMK2A	S2031	R2028C	2028	Missense	distal	-3	no	6.199	0.619	EPSD	TCGA;COSMIC	4.810	Loss
CAMK_CAMK2_CAMK2A_ST	Q92736	RYR2	Q9UQM7	CAMK2A	S2031	G2027W	2027	Missense	distal	-4	no	6.199	5.717	EPSD	TCGA;COSMIC	4.810	Down-regulation
CAMK_CAMK2_CAMK2A_ST	Q92736	RYR2	Q9UQM7	CAMK2A	S2031	R2028S	2028	Missense	distal	-3	no	6.199	1.739	EPSD	TCGA;COSMIC	4.810	Loss
CAMK_CAMK2_CAMK2A_ST	Q92736	RYR2	Q9UQM7	CAMK2A	S2808	R2803Q	2803	Missense	distal	-5	no	8.011	7.914	EPSD;PhosphoSitePlus	TCGA;COSMIC;CCLE	4.810	Down-regulation
CAMK_CAMK2_CAMK2A_ST	Q92736	RYR2	Q9UQM7	CAMK2A	S2808	S2814F	2814	Missense	distal	6	no	8.011	7.855	EPSD;PhosphoSitePlus	TCGA;COSMIC	4.810	Down-regulation
CAMK_CAMK2_CAMK2A_ST	Q92736	RYR2	Q9UQM7	CAMK2A	S2808	R2806C	2806	Missense	proximal	-2	no	8.011	7.208	EPSD;PhosphoSitePlus	TCGA	4.810	Down-regulation
CAMK_CAMK2_CAMK2A_ST	Q92736	RYR2	Q9UQM7	CAMK2A	S2808	R2805C	2805	Missense	distal	-3	no	8.011	2.431	EPSD;PhosphoSitePlus	TCGA	4.810	Loss
CAMK_CAMK2_CAMK2A_ST	Q92736	RYR2	Q9UQM7	CAMK2A	S2814	S2814F	2814	Missense	central	0	yes	6.412	0.000	PhosphoSitePlus;EPSD	TCGA;COSMIC	4.810	Loss
CAMK_CAMK2_CAMK2A_ST	Q92736	RYR2	Q9UQM7	CAMK2A	S4260	L4253F	4253	Missense	distal	-7	no	6.307	6.773	EPSD	TCGA;COSMIC;CCLE	4.810	Up-regulation
CAMK_CAMK2_CAMK2A_ST	Q92736	RYR2	Q9UQM7	CAMK2A	S4260	L4264M	4264	Missense	distal	4	no	6.307	6.390	EPSD	TCGA;COSMIC	4.810	Up-regulation
CAMK_CAMK2_CAMK2A_ST	Q92736	RYR2	Q9UQM7	CAMK2A	S4260	S4263R	4263	Missense	distal	3	no	6.307	6.212	EPSD	TCGA;COSMIC	4.810	Down-regulation
CAMK_CAMK2_CAMK2A_ST	Q92736	RYR2	Q9UQM7	CAMK2A	S4260	K4262N	4262	Missense	proximal	2	no	6.307	8.254	EPSD	TCGA;ICGC;COSMIC	4.810	Up-regulation
CAMK_CAMK2_CAMK2A_ST	Q92736	RYR2	Q9UQM7	CAMK2A	S4260	L4261P	4261	Missense	proximal	1	no	6.307	5.648	EPSD	TCGA;COSMIC	4.810	Down-regulation
CAMK_CAMK2_CAMK2A_ST	Q92736	RYR2	Q9UQM7	CAMK2A	S4317	V4319D	4319	Missense	proximal	2	no	4.039	5.855	EPSD	TCGA;COSMIC	4.810	Gain
CAMK_CAMK2_CAMK2A_ST	Q92736	RYR2	Q9UQM7	CAMK2A	T4752	G4749R	4749	Missense	distal	-3	no	0.541	5.139	EPSD	TCGA;COSMIC	4.810	Gain
CAMK_CAMK2_CAMK2A_ST	P08670	VIM	Q9UQM7	CAMK2A	S7	S8L	8	Missense	proximal	1	no	6.604	6.895	EPSD	TCGA;ICGC;COSMIC	4.810	Up-regulation
CAMK_CAMK2_CAMK2A_ST	P08670	VIM	Q9UQM7	CAMK2A	S26	S22I	22	Missense	distal	-4	no	9.397	9.019	EPSD	TCGA;ICGC;COSMIC	4.810	Down-regulation
CAMK_CAMK2_CAMK2A_ST	P08670	VIM	Q9UQM7	CAMK2A	S26	T33M	33	Missense	distal	7	no	9.397	9.405	EPSD	TCGA;ICGC;COSMIC	4.810	Up-regulation
CAMK_CAMK2_CAMK2A_ST	P08670	VIM	Q9UQM7	CAMK2A	S39	T33M	33	Missense	distal	-6	no	8.979	8.828	EPSD	TCGA;ICGC;COSMIC	4.810	Down-regulation
CAMK_CAMK2_CAMK2A_ST	P08670	VIM	Q9UQM7	CAMK2A	T48	R50H	50	Missense	proximal	2	no	8.934	7.866	EPSD	TCGA;ICGC;COSMIC	4.810	Down-regulation
CAMK_CAMK2_CAMK2A_ST	P08670	VIM	Q9UQM7	CAMK2A	S72	R71W	71	Missense	proximal	-1	no	7.061	6.478	EPSD	TCGA;ICGC;COSMIC	4.810	Down-regulation
CAMK_CAMK2_CAMK2A_ST	P08670	VIM	Q9UQM7	CAMK2A	S83	Q81L	81	Missense	proximal	-2	no	6.036	5.645	PhosphoSitePlus	TCGA;ICGC;COSMIC	4.810	Down-regulation
CAMK_CAMK2_CAMK2A_ST	P08670	VIM	Q9UQM7	CAMK2A	S226	E221K	221	Missense	distal	-5	no	7.015	7.012	EPSD	TCGA;ICGC;COSMIC	4.810	Down-regulation
CAMK_CAMK2_CAMK2A_ST	P08670	VIM	Q9UQM7	CAMK2A	S226	E221Q	221	Missense	distal	-5	no	7.015	6.960	EPSD	TCGA;ICGC;COSMIC	4.810	Down-regulation
CAMK_CAMK2_CAMK2A_ST	P08670	VIM	Q9UQM7	CAMK2A	S226	R222L	222	Missense	distal	-4	no	7.015	6.786	EPSD	TCGA;ICGC;COSMIC	4.810	Down-regulation
CAMK_CAMK2_CAMK2A_ST	P08670	VIM	Q9UQM7	CAMK2A	S226	E230K	230	Missense	distal	4	no	7.015	6.840	EPSD	TCGA;ICGC;COSMIC	4.810	Down-regulation
CAMK_CAMK2_CAMK2A_ST	P08670	VIM	Q9UQM7	CAMK2A	S226	V224L	224	Missense	proximal	-2	no	7.015	7.223	EPSD	TCGA;ICGC;COSMIC	4.810	Up-regulation
CAMK_CAMK2_CAMK2A_ST	P08670	VIM	Q9UQM7	CAMK2A	S316	R310C	310	Missense	distal	-6	no	5.044	5.239	EPSD	TCGA;ICGC;COSMIC	4.810	Up-regulation
CAMK_CAMK2_CAMK2A_ST	P08670	VIM	Q9UQM7	CAMK2A	S316	R320Q	320	Missense	distal	4	no	5.044	5.213	EPSD	TCGA;ICGC;COSMIC	4.810	Up-regulation
CAMK_CAMK2_CAMK2A_ST	P08670	VIM	Q9UQM7	CAMK2A	S316	Y319C	319	Missense	distal	3	no	5.044	5.025	EPSD	TCGA;ICGC;COSMIC	4.810	Down-regulation
CAMK_CAMK2_CAMK2A_ST	P08670	VIM	Q9UQM7	CAMK2A	S316	R310S	310	Missense	distal	-6	no	5.044	5.088	EPSD	TCGA;ICGC;COSMIC	4.810	Up-regulation
CAMK_CAMK2_CAMK2A_ST	P08670	VIM	Q9UQM7	CAMK2A	T449	R450T	450	Missense	proximal	1	no	5.469	5.538	EPSD	TCGA;ICGC;COSMIC	4.810	Up-regulation
CAMK_CAMK2_CAMK2A_ST	O14713	ITGB1BP1	Q9UQM7	CAMK2A	S10	R3H	3	Missense	distal	-7	no	5.399	5.339	EPSD	TCGA;ICGC;COSMIC	4.810	Down-regulation
CAMK_CAMK2_CAMK2A_ST	O14713	ITGB1BP1	Q9UQM7	CAMK2A	S10	R3C	3	Missense	distal	-7	no	5.399	6.068	EPSD	TCGA;ICGC;COSMIC	4.810	Up-regulation
CAMK_CAMK2_CAMK2A_ST	O14713	ITGB1BP1	Q9UQM7	CAMK2A	S10	Q15H	15	Missense	distal	5	no	5.399	5.514	EPSD	TCGA;ICGC;COSMIC	4.810	Up-regulation
CAMK_CAMK2_CAMK2A_ST	O14713	ITGB1BP1	Q9UQM7	CAMK2A	S10	S10N	10	Missense	central	0	yes	5.399	0.000	EPSD	TCGA;ICGC;COSMIC	4.810	Loss
CAMK_CAMK2_CAMK2A_ST	O14713	ITGB1BP1	Q9UQM7	CAMK2A	S11	Q15H	15	Missense	distal	4	no	8.579	8.522	EPSD	TCGA;ICGC;COSMIC	4.810	Down-regulation
CAMK_CAMK2_CAMK2A_ST	O14713	ITGB1BP1	Q9UQM7	CAMK2A	S11	S10N	10	Missense	proximal	-1	no	8.579	8.444	EPSD	TCGA;ICGC;COSMIC	4.810	Down-regulation
CAMK_CAMK2_CAMK2A_ST	O14713	ITGB1BP1	Q9UQM7	CAMK2A	S14	Q15H	15	Missense	proximal	1	no	4.664	5.204	EPSD	TCGA;ICGC;COSMIC	4.810	Gain
CAMK_CAMK2_CAMK2A_ST	O14713	ITGB1BP1	Q9UQM7	CAMK2A	S16	Q15H	15	Missense	proximal	-1	no	6.890	6.791	EPSD	TCGA;ICGC;COSMIC	4.810	Down-regulation
CAMK_CAMK2_CAMK2A_ST	O14713	ITGB1BP1	Q9UQM7	CAMK2A	S16	S10N	10	Missense	distal	-6	no	6.890	6.992	EPSD	TCGA;ICGC;COSMIC	4.810	Up-regulation
CAMK_CAMK2_CAMK2A_ST	O14713	ITGB1BP1	Q9UQM7	CAMK2A	S16	K22T	22	Missense	distal	6	no	6.890	6.874	EPSD	TCGA;ICGC	4.810	Down-regulation
CAMK_CAMK2_CAMK2A_ST	O14713	ITGB1BP1	Q9UQM7	CAMK2A	S17	Q15H	15	Missense	proximal	-2	no	7.238	6.901	EPSD	TCGA;ICGC;COSMIC	4.810	Down-regulation
CAMK_CAMK2_CAMK2A_ST	O14713	ITGB1BP1	Q9UQM7	CAMK2A	S17	S10N	10	Missense	distal	-7	no	7.238	7.335	EPSD	TCGA;ICGC;COSMIC	4.810	Up-regulation
CAMK_CAMK2_CAMK2A_ST	O14713	ITGB1BP1	Q9UQM7	CAMK2A	S17	K22T	22	Missense	distal	5	no	7.238	7.110	EPSD	TCGA;ICGC	4.810	Down-regulation
CAMK_CAMK2_CAMK2A_ST	O14713	ITGB1BP1	Q9UQM7	CAMK2A	S20	K22T	22	Missense	proximal	2	no	4.442	4.933	EPSD	TCGA;ICGC	4.810	Gain
CAMK_CAMK2_CAMK2A_ST	O14713	ITGB1BP1	Q9UQM7	CAMK2A	S25	S28C	28	Missense	distal	3	no	9.192	8.835	EPSD	TCGA;ICGC;COSMIC	4.810	Down-regulation
CAMK_CAMK2_CAMK2A_ST	O14713	ITGB1BP1	Q9UQM7	CAMK2A	S25	S25F	25	Missense	central	0	yes	9.192	0.000	EPSD	TCGA;ICGC;COSMIC	4.810	Loss
CAMK_CAMK2_CAMK2A_ST	O14713	ITGB1BP1	Q9UQM7	CAMK2A	S25	K22T	22	Missense	distal	-3	no	9.192	6.404	EPSD	TCGA;ICGC	4.810	Down-regulation
CAMK_CAMK2_CAMK2A_ST	O14713	ITGB1BP1	Q9UQM7	CAMK2A	T38	S41N	41	Missense	distal	3	no	7.523	7.409	PhosphoSitePlus	TCGA;ICGC;COSMIC	4.810	Down-regulation
CAMK_CAMK2_CAMK2A_ST	O14713	ITGB1BP1	Q9UQM7	CAMK2A	S41	S41N	41	Missense	central	0	yes	5.153	0.000	EPSD	TCGA;ICGC;COSMIC	4.810	Loss
CAMK_CAMK2_CAMK2A_ST	P31645	SLC6A4	Q9UQM7	CAMK2A	S13	S13L	13	Missense	central	0	yes	5.858	0.000	PhosphoSitePlus	TCGA;ICGC;COSMIC	4.810	Loss
CAMK_CAMK2_CAMK2A_ST	P31645	SLC6A4	Q9UQM7	CAMK2A	S13	Q9E	9	Missense	distal	-4	no	5.858	6.020	PhosphoSitePlus	TCGA;ICGC;COSMIC	4.810	Up-regulation
CAMK_CAMK2_CAMK2A_ST	P31645	SLC6A4	Q9UQM7	CAMK2A	S13	S8Y	8	Missense	distal	-5	no	5.858	5.866	PhosphoSitePlus	TCGA;ICGC;COSMIC;GDSC	4.810	Up-regulation
CAMK_CAMK2_CAMK2A_ST	P31645	SLC6A4	Q9UQM7	CAMK2A	S40	S44P	44	Missense	distal	4	no	6.166	5.993	EPSD	TCGA;ICGC;COSMIC	4.810	Down-regulation
CAMK_CAMK2_CAMK2A_ST	P31645	SLC6A4	Q9UQM7	CAMK2A	S40	T33I	33	Missense	distal	-7	no	6.166	6.237	EPSD	TCGA;ICGC;COSMIC	4.810	Up-regulation
CAMK_CAMK2_CAMK2A_ST	P31645	SLC6A4	Q9UQM7	CAMK2A	S149	G146R	146	Missense	distal	-3	no	0.901	5.499	EPSD	TCGA;ICGC;COSMIC	4.810	Gain
CAMK_CAMK2_CAMK2A_ST	P31645	SLC6A4	Q9UQM7	CAMK2A	S611	R607C	607	Missense	distal	-4	no	5.054	4.420	EPSD	TCGA;ICGC	4.810	Loss
CAMK_CAMK2_CAMK2A_ST	P31645	SLC6A4	Q9UQM7	CAMK2A	T613	R607C	607	Missense	distal	-6	no	5.213	5.407	EPSD	TCGA;ICGC	4.810	Up-regulation
CAMK_CAMK2_CAMK2A_ST	P21333	FLNA	Q9UQM7	CAMK2A	S123	D125N	125	Missense	proximal	2	no	7.119	6.108	EPSD	TCGA;ICGC;COSMIC;GDSC	4.810	Down-regulation
CAMK_CAMK2_CAMK2A_ST	P21333	FLNA	Q9UQM7	CAMK2A	S189	R196Q	196	Missense	distal	7	no	5.741	5.623	EPSD	TCGA;ICGC;COSMIC	4.810	Down-regulation
CAMK_CAMK2_CAMK2A_ST	P21333	FLNA	Q9UQM7	CAMK2A	S189	N187K	187	Missense	proximal	-2	no	5.741	5.839	EPSD	TCGA;ICGC;COSMIC	4.810	Up-regulation
CAMK_CAMK2_CAMK2A_ST	P21333	FLNA	Q9UQM7	CAMK2A	S189	I185V	185	Missense	distal	-4	no	5.741	5.839	EPSD	TCGA;ICGC;COSMIC	4.810	Up-regulation
CAMK_CAMK2_CAMK2A_ST	P21333	FLNA	Q9UQM7	CAMK2A	S343	K338Q	338	Missense	distal	-5	no	5.546	5.494	EPSD	TCGA;ICGC;COSMIC	4.810	Down-regulation
CAMK_CAMK2_CAMK2A_ST	P21333	FLNA	Q9UQM7	CAMK2A	S343	P348S	348	Missense	distal	5	no	5.546	5.776	EPSD	TCGA;ICGC;COSMIC	4.810	Up-regulation
CAMK_CAMK2_CAMK2A_ST	P21333	FLNA	Q9UQM7	CAMK2A	S377	E371D	371	Missense	distal	-6	no	4.795	4.992	EPSD	TCGA;ICGC	4.810	Gain
CAMK_CAMK2_CAMK2A_ST	P21333	FLNA	Q9UQM7	CAMK2A	S377	E371K	371	Missense	distal	-6	no	4.795	4.896	EPSD	TCGA;ICGC	4.810	Gain
CAMK_CAMK2_CAMK2A_ST	P21333	FLNA	Q9UQM7	CAMK2A	S377	V372A	372	Missense	distal	-5	no	4.795	4.916	EPSD	TCGA;ICGC	4.810	Gain
CAMK_CAMK2_CAMK2A_ST	P21333	FLNA	Q9UQM7	CAMK2A	S630	D628N	628	Missense	proximal	-2	no	6.038	6.470	EPSD	TCGA;ICGC;COSMIC	4.810	Up-regulation
CAMK_CAMK2_CAMK2A_ST	P21333	FLNA	Q9UQM7	CAMK2A	S630	D625N	625	Missense	distal	-5	no	6.038	6.050	EPSD	TCGA;ICGC;COSMIC	4.810	Up-regulation
CAMK_CAMK2_CAMK2A_ST	P21333	FLNA	Q9UQM7	CAMK2A	S630	V633M	633	Missense	distal	3	no	6.038	5.879	EPSD	TCGA;ICGC;COSMIC	4.810	Down-regulation
CAMK_CAMK2_CAMK2A_ST	P21333	FLNA	Q9UQM7	CAMK2A	S630	D632Y	632	Missense	proximal	2	no	6.038	2.462	EPSD	TCGA;ICGC;COSMIC	4.810	Loss
CAMK_CAMK2_CAMK2A_ST	P21333	FLNA	Q9UQM7	CAMK2A	S630	Y635C	635	Missense	distal	5	no	6.038	5.794	EPSD	TCGA;ICGC;COSMIC	4.810	Down-regulation
CAMK_CAMK2_CAMK2A_ST	P21333	FLNA	Q9UQM7	CAMK2A	S630	K626R	626	Missense	distal	-4	no	6.038	6.029	EPSD	TCGA;ICGC	4.810	Down-regulation
CAMK_CAMK2_CAMK2A_ST	P21333	FLNA	Q9UQM7	CAMK2A	S630	Y635H	635	Missense	distal	5	no	6.038	6.200	EPSD	TCGA;ICGC;COSMIC	4.810	Up-regulation
CAMK_CAMK2_CAMK2A_ST	P21333	FLNA	Q9UQM7	CAMK2A	S748	G750E	750	Missense	proximal	2	no	4.247	5.165	EPSD	TCGA;ICGC	4.810	Gain
CAMK_CAMK2_CAMK2A_ST	P21333	FLNA	Q9UQM7	CAMK2A	S869	V875M	875	Missense	distal	6	no	5.871	5.955	EPSD	TCGA;ICGC;COSMIC	4.810	Up-regulation
CAMK_CAMK2_CAMK2A_ST	P21333	FLNA	Q9UQM7	CAMK2A	S869	P868S	868	Missense	proximal	-1	no	5.871	6.056	EPSD	TCGA;ICGC;COSMIC	4.810	Up-regulation
CAMK_CAMK2_CAMK2A_ST	P21333	FLNA	Q9UQM7	CAMK2A	S968	P967S	967	Missense	proximal	-1	no	6.182	6.368	EPSD	TCGA;ICGC;COSMIC	4.810	Up-regulation
CAMK_CAMK2_CAMK2A_ST	P21333	FLNA	Q9UQM7	CAMK2A	S968	F961L	961	Missense	distal	-7	no	6.182	5.716	EPSD	TCGA;ICGC	4.810	Down-regulation
CAMK_CAMK2_CAMK2A_ST	P21333	FLNA	Q9UQM7	CAMK2A	S1029	D1027E	1027	Missense	proximal	-2	no	4.505	4.811	EPSD	TCGA;ICGC;COSMIC	4.810	Gain
CAMK_CAMK2_CAMK2A_ST	P21333	FLNA	Q9UQM7	CAMK2A	T1275	R1272C	1272	Missense	distal	-3	no	6.437	0.856	EPSD	TCGA;ICGC;COSMIC	4.810	Loss
CAMK_CAMK2_CAMK2A_ST	P21333	FLNA	Q9UQM7	CAMK2A	T1275	Q1268H	1268	Missense	distal	-7	no	6.437	6.320	EPSD	TCGA;ICGC	4.810	Down-regulation
CAMK_CAMK2_CAMK2A_ST	P21333	FLNA	Q9UQM7	CAMK2A	T1275	A1282T	1282	Missense	distal	7	no	6.437	6.486	EPSD	TCGA;ICGC	4.810	Up-regulation
CAMK_CAMK2_CAMK2A_ST	P21333	FLNA	Q9UQM7	CAMK2A	T1275	R1272H	1272	Missense	distal	-3	no	6.437	0.940	EPSD	TCGA;ICGC;COSMIC	4.810	Loss
CAMK_CAMK2_CAMK2A_ST	P21333	FLNA	Q9UQM7	CAMK2A	T1286	R1283W	1283	Missense	distal	-3	no	7.466	-4.554	EPSD	TCGA;ICGC;COSMIC	4.810	Loss
CAMK_CAMK2_CAMK2A_ST	P21333	FLNA	Q9UQM7	CAMK2A	T1286	P1291L	1291	Missense	distal	5	no	7.466	7.407	EPSD	TCGA;ICGC;COSMIC	4.810	Down-regulation
CAMK_CAMK2_CAMK2A_ST	P21333	FLNA	Q9UQM7	CAMK2A	T1286	A1282T	1282	Missense	distal	-4	no	7.466	7.176	EPSD	TCGA;ICGC	4.810	Down-regulation
CAMK_CAMK2_CAMK2A_ST	P21333	FLNA	Q9UQM7	CAMK2A	S1330	G1337V	1337	Missense	distal	7	no	5.797	5.778	EPSD	TCGA;ICGC;COSMIC	4.810	Down-regulation
CAMK_CAMK2_CAMK2A_ST	P21333	FLNA	Q9UQM7	CAMK2A	S1409	P1416L	1416	Missense	distal	7	no	6.215	6.280	EPSD	TCGA;ICGC;COSMIC	4.810	Up-regulation
CAMK_CAMK2_CAMK2A_ST	P21333	FLNA	Q9UQM7	CAMK2A	S1423	P1416L	1416	Missense	distal	-7	no	5.362	5.328	EPSD	TCGA;ICGC;COSMIC	4.810	Down-regulation
CAMK_CAMK2_CAMK2A_ST	P21333	FLNA	Q9UQM7	CAMK2A	S1423	G1420A	1420	Missense	distal	-3	no	5.362	5.540	EPSD	TCGA;ICGC;COSMIC	4.810	Up-regulation
CAMK_CAMK2_CAMK2A_ST	P21333	FLNA	Q9UQM7	CAMK2A	T1557	G1554R	1554	Missense	distal	-3	no	1.868	6.466	EPSD	TCGA;ICGC;COSMIC	4.810	Gain
CAMK_CAMK2_CAMK2A_ST	P21333	FLNA	Q9UQM7	CAMK2A	S1812	A1816T	1816	Missense	distal	4	no	6.255	6.216	EPSD	TCGA	4.810	Down-regulation
CAMK_CAMK2_CAMK2A_ST	P21333	FLNA	Q9UQM7	CAMK2A	S1812	R1809W	1809	Missense	distal	-3	no	6.255	-5.765	EPSD	TCGA	4.810	Loss
CAMK_CAMK2_CAMK2A_ST	P21333	FLNA	Q9UQM7	CAMK2A	S1812	G1813C	1813	Missense	proximal	1	no	6.255	6.536	EPSD	TCGA;COSMIC	4.810	Up-regulation
CAMK_CAMK2_CAMK2A_ST	P21333	FLNA	Q9UQM7	CAMK2A	S2152	S2152L	2152	Missense	central	0	yes	5.835	0.000	EPSD	TCGA;COSMIC	4.810	Loss
CAMK_CAMK2_CAMK2A_ST	P21333	FLNA	Q9UQM7	CAMK2A	S2152	R2148S	2148	Missense	distal	-4	no	5.835	5.904	EPSD	TCGA;COSMIC	4.810	Up-regulation
CAMK_CAMK2_CAMK2A_ST	P21333	FLNA	Q9UQM7	CAMK2A	S2180	Q2177H	2177	Missense	distal	-3	no	5.438	3.512	EPSD	TCGA;COSMIC	4.810	Loss
CAMK_CAMK2_CAMK2A_ST	P21333	FLNA	Q9UQM7	CAMK2A	S2284	E2282K	2282	Missense	proximal	-2	no	6.163	6.386	EPSD	TCGA;COSMIC	4.810	Up-regulation
CAMK_CAMK2_CAMK2A_ST	P21333	FLNA	Q9UQM7	CAMK2A	S2284	R2288H	2288	Missense	distal	4	no	6.163	6.274	EPSD	TCGA;COSMIC	4.810	Up-regulation
CAMK_CAMK2_CAMK2A_ST	P21333	FLNA	Q9UQM7	CAMK2A	S2284	K2289N	2289	Missense	distal	5	no	6.163	6.083	EPSD	TCGA	4.810	Down-regulation
CAMK_CAMK2_CAMK2A_ST	P21333	FLNA	Q9UQM7	CAMK2A	S2292	R2288H	2288	Missense	distal	-4	no	5.353	5.229	EPSD	TCGA;COSMIC	4.810	Down-regulation
CAMK_CAMK2_CAMK2A_ST	P21333	FLNA	Q9UQM7	CAMK2A	S2292	K2289N	2289	Missense	distal	-3	no	5.353	2.786	EPSD	TCGA	4.810	Loss
CAMK_CAMK2_CAMK2A_ST	P21333	FLNA	Q9UQM7	CAMK2A	T2336	R2334H	2334	Missense	proximal	-2	no	5.750	5.630	EPSD	TCGA;COSMIC;GDSC;CCLE	4.810	Down-regulation
CAMK_CAMK2_CAMK2A_ST	P21333	FLNA	Q9UQM7	CAMK2A	T2336	E2342K	2342	Missense	distal	6	no	5.750	5.699	EPSD	TCGA	4.810	Down-regulation
CAMK_CAMK2_CAMK2A_ST	P21333	FLNA	Q9UQM7	CAMK2A	T2336	A2332T	2332	Missense	distal	-4	no	5.750	5.460	EPSD	TCGA;COSMIC	4.810	Down-regulation
CAMK_CAMK2_CAMK2A_ST	P21333	FLNA	Q9UQM7	CAMK2A	S2352	N2348D	2348	Missense	distal	-4	no	5.610	5.547	EPSD	TCGA;COSMIC	4.810	Down-regulation
CAMK_CAMK2_CAMK2A_ST	P21333	FLNA	Q9UQM7	CAMK2A	S2352	G2359V	2359	Missense	distal	7	no	5.610	5.591	EPSD	TCGA;COSMIC	4.810	Down-regulation
CAMK_CAMK2_CAMK2A_ST	P21333	FLNA	Q9UQM7	CAMK2A	S2352	S2352Y	2352	Missense	central	0	yes	5.610	0.000	EPSD	TCGA;COSMIC	4.810	Loss
CAMK_CAMK2_CAMK2A_ST	P21333	FLNA	Q9UQM7	CAMK2A	S2370	S2372L	2372	Missense	proximal	2	no	5.270	4.957	EPSD	TCGA;COSMIC	4.810	Down-regulation
CAMK_CAMK2_CAMK2A_ST	P21333	FLNA	Q9UQM7	CAMK2A	S2370	H2369Y	2369	Missense	proximal	-1	no	5.270	5.076	EPSD	TCGA;COSMIC	4.810	Down-regulation
CAMK_CAMK2_CAMK2A_ST	P21333	FLNA	Q9UQM7	CAMK2A	S2370	A2363V	2363	Missense	distal	-7	no	5.270	5.710	EPSD	TCGA;COSMIC	4.810	Up-regulation
CAMK_CAMK2_CAMK2A_ST	P21333	FLNA	Q9UQM7	CAMK2A	S2370	P2371L	2371	Missense	proximal	1	no	5.270	5.928	EPSD	TCGA;COSMIC	4.810	Up-regulation
CAMK_CAMK2_CAMK2A_ST	P21333	FLNA	Q9UQM7	CAMK2A	S2370	A2374S	2374	Missense	distal	4	no	5.270	5.324	EPSD	TCGA;COSMIC	4.810	Up-regulation
CAMK_CAMK2_CAMK2A_ST	P21333	FLNA	Q9UQM7	CAMK2A	S2523	G2518C	2518	Missense	distal	-5	no	9.339	9.231	PhosphoSitePlus	TCGA;COSMIC	4.810	Down-regulation
CAMK_CAMK2_CAMK2A_ST	P21333	FLNA	Q9UQM7	CAMK2A	S2523	S2526I	2526	Missense	distal	3	no	9.339	9.094	PhosphoSitePlus	TCGA	4.810	Down-regulation
CAMK_CAMK2_CAMK2A_ST	P21333	FLNA	Q9UQM7	CAMK2A	S2615	R2612W	2612	Missense	distal	-3	no	6.393	-5.627	EPSD	TCGA;GDSC	4.810	Loss
CAMK_CAMK2_CAMK2A_ST	P21333	FLNA	Q9UQM7	CAMK2A	S2615	V2609M	2609	Missense	distal	-6	no	6.393	6.272	EPSD	TCGA;COSMIC;GDSC;CCLE	4.810	Down-regulation
CAMK_CAMK2_CAMK2A_ST	P21333	FLNA	Q9UQM7	CAMK2A	S2615	S2617P	2617	Missense	proximal	2	no	6.393	5.916	EPSD	TCGA;COSMIC	4.810	Down-regulation
CAMK_CAMK2_CAMK2A_ST	Q96A00	PPP1R14A	Q9UQM7	CAMK2A	S128	P129T	129	Missense	proximal	1	no	9.054	9.302	EPSD	TCGA;COSMIC	4.810	Up-regulation
CAMK_CAMK2_CAMK2A_ST	Q96A00	PPP1R14A	Q9UQM7	CAMK2A	S130	P129T	129	Missense	proximal	-1	no	5.910	5.936	PhosphoSitePlus	TCGA;COSMIC	4.810	Up-regulation
CAMK_CAMK2_CAMK2A_ST	O43526	KCNQ2	Q9UQM7	CAMK2A	T368	R365Q	365	Missense	distal	-3	no	5.128	1.556	EPSD	TCGA;ICGC;COSMIC	4.810	Loss
CAMK_CAMK2_CAMK2A_ST	O43526	KCNQ2	Q9UQM7	CAMK2A	T368	Y362H	362	Missense	distal	-6	no	5.128	5.006	EPSD	TCGA;ICGC;COSMIC	4.810	Down-regulation
CAMK_CAMK2_CAMK2A_ST	O43526	KCNQ2	Q9UQM7	CAMK2A	T368	M371I	371	Missense	distal	3	no	5.128	5.064	EPSD	TCGA;ICGC;COSMIC	4.810	Down-regulation
CAMK_CAMK2_CAMK2A_ST	O43526	KCNQ2	Q9UQM7	CAMK2A	T368	T366M	366	Missense	proximal	-2	no	5.128	5.354	EPSD	TCGA;ICGC;COSMIC	4.810	Up-regulation
CAMK_CAMK2_CAMK2A_ST	O43526	KCNQ2	Q9UQM7	CAMK2A	T368	P370L	370	Missense	proximal	2	no	5.128	5.292	EPSD	TCGA;ICGC;COSMIC	4.810	Up-regulation
CAMK_CAMK2_CAMK2A_ST	O43526	KCNQ2	Q9UQM7	CAMK2A	T368	E364K	364	Missense	distal	-4	no	5.128	5.079	EPSD	TCGA;ICGC;COSMIC	4.810	Down-regulation
CAMK_CAMK2_CAMK2A_ST	O43526	KCNQ2	Q9UQM7	CAMK2A	S445	R442H	442	Missense	distal	-3	no	7.611	2.114	EPSD	TCGA;COSMIC;GDSC;CCLE	4.810	Loss
CAMK_CAMK2_CAMK2A_ST	O43526	KCNQ2	Q9UQM7	CAMK2A	S445	F444L	444	Missense	proximal	-1	no	7.611	7.742	EPSD	TCGA	4.810	Up-regulation
CAMK_CAMK2_CAMK2A_ST	O43526	KCNQ2	Q9UQM7	CAMK2A	S468	D470N	470	Missense	proximal	2	no	9.877	8.866	EPSD	TCGA;COSMIC	4.810	Down-regulation
CAMK_CAMK2_CAMK2A_ST	O43526	KCNQ2	Q9UQM7	CAMK2A	S468	E474Q	474	Missense	distal	6	no	9.877	9.865	EPSD	TCGA;COSMIC	4.810	Down-regulation
CAMK_CAMK2_CAMK2A_ST	O43526	KCNQ2	Q9UQM7	CAMK2A	S468	D475N	475	Missense	distal	7	no	9.877	9.859	EPSD	TCGA;COSMIC	4.810	Down-regulation
CAMK_CAMK2_CAMK2A_ST	O43526	KCNQ2	Q9UQM7	CAMK2A	S485	G487R	487	Missense	proximal	2	no	4.473	4.892	EPSD	TCGA;COSMIC	4.810	Gain
CAMK_CAMK2_CAMK2A_ST	O43526	KCNQ2	Q9UQM7	CAMK2A	S503	S503L	503	Missense	central	0	yes	4.957	0.000	EPSD	TCGA;COSMIC	4.810	Loss
CAMK_CAMK2_CAMK2A_ST	O43526	KCNQ2	Q9UQM7	CAMK2A	S503	Q505L	505	Missense	proximal	2	no	4.957	4.850	EPSD	TCGA;COSMIC	4.810	Down-regulation
CAMK_CAMK2_CAMK2A_ST	O43526	KCNQ2	Q9UQM7	CAMK2A	S503	R497C	497	Missense	distal	-6	no	4.957	5.151	EPSD	TCGA;COSMIC	4.810	Up-regulation
CAMK_CAMK2_CAMK2A_ST	O43526	KCNQ2	Q9UQM7	CAMK2A	S503	E508G	508	Missense	distal	5	no	4.957	4.835	EPSD	TCGA;COSMIC	4.810	Down-regulation
CAMK_CAMK2_CAMK2A_ST	O43526	KCNQ2	Q9UQM7	CAMK2A	S503	A502V	502	Missense	proximal	-1	no	4.957	4.733	EPSD	TCGA;COSMIC	4.810	Loss
CAMK_CAMK2_CAMK2A_ST	O43526	KCNQ2	Q9UQM7	CAMK2A	S503	N506S	506	Missense	distal	3	no	4.957	5.071	EPSD	TCGA	4.810	Up-regulation
CAMK_CAMK2_CAMK2A_ST	O43526	KCNQ2	Q9UQM7	CAMK2A	S507	S503L	503	Missense	distal	-4	no	10.358	10.061	EPSD	TCGA;COSMIC	4.810	Down-regulation
CAMK_CAMK2_CAMK2A_ST	O43526	KCNQ2	Q9UQM7	CAMK2A	S507	Q505L	505	Missense	proximal	-2	no	10.358	9.967	EPSD	TCGA;COSMIC	4.810	Down-regulation
CAMK_CAMK2_CAMK2A_ST	O43526	KCNQ2	Q9UQM7	CAMK2A	S507	E508G	508	Missense	proximal	1	no	10.358	9.775	EPSD	TCGA;COSMIC	4.810	Down-regulation
CAMK_CAMK2_CAMK2A_ST	O43526	KCNQ2	Q9UQM7	CAMK2A	S507	A502V	502	Missense	distal	-5	no	10.358	10.237	EPSD	TCGA;COSMIC	4.810	Down-regulation
CAMK_CAMK2_CAMK2A_ST	O43526	KCNQ2	Q9UQM7	CAMK2A	S507	N506S	506	Missense	proximal	-1	no	10.358	10.494	EPSD	TCGA	4.810	Up-regulation
CAMK_CAMK2_CAMK2A_ST	O43526	KCNQ2	Q9UQM7	CAMK2A	S803	F805L	805	Missense	proximal	2	no	4.198	5.136	EPSD	TCGA;COSMIC	4.810	Gain
CAMK_CAMK2_CAMK2A_ST	O43526	KCNQ2	Q9UQM7	CAMK2A	S810	F805L	805	Missense	distal	-5	no	5.214	5.105	EPSD	TCGA;COSMIC	4.810	Down-regulation
CAMK_CAMK2_CAMK2A_ST	O43526	KCNQ2	Q9UQM7	CAMK2A	S810	S808Y	808	Missense	proximal	-2	no	5.214	5.138	EPSD	TCGA;COSMIC	4.810	Down-regulation
CAMK_CAMK2_CAMK2A_ST	O43526	KCNQ2	Q9UQM7	CAMK2A	S810	N813K	813	Missense	distal	3	no	5.214	5.299	EPSD	TCGA;COSMIC	4.810	Up-regulation
CAMK_CAMK2_CAMK2A_ST	O43526	KCNQ2	Q9UQM7	CAMK2A	S810	I807V	807	Missense	distal	-3	no	5.214	4.364	EPSD	TCGA;COSMIC	4.810	Loss
CAMK_CAMK2_CAMK2A_ST	O43526	KCNQ2	Q9UQM7	CAMK2A	T857	P852L	852	Missense	distal	-5	no	7.599	7.506	EPSD	TCGA;COSMIC	4.810	Down-regulation
CAMK_CAMK2_CAMK2A_ST	O43526	KCNQ2	Q9UQM7	CAMK2A	T857	P851T	851	Missense	distal	-6	no	7.599	7.619	EPSD	TCGA;COSMIC	4.810	Up-regulation
CAMK_CAMK2_CAMK2A_ST	O43526	KCNQ2	Q9UQM7	CAMK2A	T857	P852Q	852	Missense	distal	-5	no	7.599	7.429	EPSD	TCGA;COSMIC	4.810	Down-regulation
CAMK_CAMK2_CAMK2A_ST	O43526	KCNQ2	Q9UQM7	CAMK2A	T857	P861L	861	Missense	distal	4	no	7.599	7.561	EPSD	TCGA;COSMIC;CCLE	4.810	Down-regulation
CAMK_CAMK2_CAMK2A_ST	O43526	KCNQ2	Q9UQM7	CAMK2A	T857	G863D	863	Missense	distal	6	no	7.599	7.688	EPSD	TCGA;COSMIC	4.810	Up-regulation
CAMK_CAMK2_CAMK2A_ST	O43526	KCNQ2	Q9UQM7	CAMK2A	T857	S855L	855	Missense	proximal	-2	no	7.599	7.496	EPSD	TCGA;COSMIC	4.810	Down-regulation
CAMK_CAMK2_CAMK2A_ST	Q06210	GFPT1	Q9UQM7	CAMK2A	S205	V199I	199	Missense	distal	-6	no	6.530	6.465	EPSD	TCGA;ICGC	4.810	Down-regulation
CAMK_CAMK2_CAMK2A_ST	Q06210	GFPT1	Q9UQM7	CAMK2A	S253	S253R	253	Missense	central	0	yes	6.269	0.000	EPSD	TCGA;ICGC;COSMIC	4.810	Loss
CAMK_CAMK2_CAMK2A_ST	Q06210	GFPT1	Q9UQM7	CAMK2A	S253	R258H	258	Missense	distal	5	no	6.269	6.383	EPSD	TCGA;ICGC;COSMIC	4.810	Up-regulation
CAMK_CAMK2_CAMK2A_ST	Q06210	GFPT1	Q9UQM7	CAMK2A	S253	G252R	252	Missense	proximal	-1	no	6.269	6.327	EPSD	TCGA;ICGC;COSMIC	4.810	Up-regulation
CAMK_CAMK2_CAMK2A_ST	Q06210	GFPT1	Q9UQM7	CAMK2A	S261	R258H	258	Missense	distal	-3	no	7.159	1.661	PhosphoSitePlus	TCGA;ICGC;COSMIC	4.810	Loss
CAMK_CAMK2_CAMK2A_ST	P35222	CTNNB1	Q9UQM7	CAMK2A	S37	G34R	34	Missense	distal	-3	no	4.979	9.576	EPSD	TCGA;COSMIC	4.810	Up-regulation
CAMK_CAMK2_CAMK2A_ST	P35222	CTNNB1	Q9UQM7	CAMK2A	S37	G34V	34	Missense	distal	-3	no	4.979	4.455	EPSD	TCGA;COSMIC;CCLE	4.810	Loss
CAMK_CAMK2_CAMK2A_ST	P35222	CTNNB1	Q9UQM7	CAMK2A	S37	T41A	41	Missense	distal	4	no	4.979	5.017	EPSD	TCGA;COSMIC;GDSC;CCLE	4.810	Up-regulation
CAMK_CAMK2_CAMK2A_ST	P35222	CTNNB1	Q9UQM7	CAMK2A	S37	G34E	34	Missense	distal	-3	no	4.979	4.458	EPSD	TCGA;COSMIC;GDSC;CCLE	4.810	Loss
CAMK_CAMK2_CAMK2A_ST	P35222	CTNNB1	Q9UQM7	CAMK2A	S37	S37C	37	Missense	central	0	yes	4.979	0.000	EPSD	TCGA;COSMIC;GDSC;CCLE	4.810	Loss
CAMK_CAMK2_CAMK2A_ST	P35222	CTNNB1	Q9UQM7	CAMK2A	S37	S37F	37	Missense	central	0	yes	4.979	0.000	EPSD	TCGA;COSMIC;GDSC;CCLE	4.810	Loss
CAMK_CAMK2_CAMK2A_ST	P35222	CTNNB1	Q9UQM7	CAMK2A	S37	S33F	33	Missense	distal	-4	no	4.979	4.461	EPSD	TCGA;COSMIC;GDSC;CCLE	4.810	Loss
CAMK_CAMK2_CAMK2A_ST	P35222	CTNNB1	Q9UQM7	CAMK2A	S37	D32H	32	Missense	distal	-5	no	4.979	4.802	EPSD	TCGA;COSMIC	4.810	Loss
CAMK_CAMK2_CAMK2A_ST	P35222	CTNNB1	Q9UQM7	CAMK2A	S37	D32G	32	Missense	distal	-5	no	4.979	4.963	EPSD	TCGA;COSMIC	4.810	Down-regulation
CAMK_CAMK2_CAMK2A_ST	P35222	CTNNB1	Q9UQM7	CAMK2A	S37	T41I	41	Missense	distal	4	no	4.979	4.806	EPSD	TCGA;COSMIC	4.810	Loss
CAMK_CAMK2_CAMK2A_ST	P35222	CTNNB1	Q9UQM7	CAMK2A	S37	S33A	33	Missense	distal	-4	no	4.979	4.987	EPSD	TCGA;COSMIC	4.810	Up-regulation
CAMK_CAMK2_CAMK2A_ST	P35222	CTNNB1	Q9UQM7	CAMK2A	S37	S33Y	33	Missense	distal	-4	no	4.979	4.654	EPSD	TCGA;COSMIC;GDSC;CCLE	4.810	Loss
CAMK_CAMK2_CAMK2A_ST	P35222	CTNNB1	Q9UQM7	CAMK2A	S37	D32V	32	Missense	distal	-5	no	4.979	4.812	EPSD	TCGA;COSMIC;CCLE	4.810	Down-regulation
CAMK_CAMK2_CAMK2A_ST	P35222	CTNNB1	Q9UQM7	CAMK2A	S37	S33P	33	Missense	distal	-4	no	4.979	4.600	EPSD	TCGA;COSMIC;CCLE	4.810	Loss
CAMK_CAMK2_CAMK2A_ST	P35222	CTNNB1	Q9UQM7	CAMK2A	S37	H36P	36	Missense	proximal	-1	no	4.979	4.735	EPSD	TCGA;COSMIC;CCLE	4.810	Loss
CAMK_CAMK2_CAMK2A_ST	P35222	CTNNB1	Q9UQM7	CAMK2A	S37	D32Y	32	Missense	distal	-5	no	4.979	4.936	EPSD	TCGA;COSMIC;CCLE	4.810	Down-regulation
CAMK_CAMK2_CAMK2A_ST	P35222	CTNNB1	Q9UQM7	CAMK2A	S37	I35S	35	Missense	proximal	-2	no	4.979	5.046	EPSD	TCGA;COSMIC	4.810	Up-regulation
CAMK_CAMK2_CAMK2A_ST	P35222	CTNNB1	Q9UQM7	CAMK2A	S37	S37Y	37	Missense	central	0	yes	4.979	0.000	EPSD	TCGA;COSMIC	4.810	Loss
CAMK_CAMK2_CAMK2A_ST	P35222	CTNNB1	Q9UQM7	CAMK2A	S37	S33C	33	Missense	distal	-4	no	4.979	4.276	EPSD	TCGA;COSMIC;GDSC;CCLE	4.810	Loss
CAMK_CAMK2_CAMK2A_ST	P35222	CTNNB1	Q9UQM7	CAMK2A	S37	S37A	37	Missense	central	0	yes	4.979	0.000	EPSD	TCGA;COSMIC;GDSC;CCLE	4.810	Loss
CAMK_CAMK2_CAMK2A_ST	P35222	CTNNB1	Q9UQM7	CAMK2A	S37	D32N	32	Missense	distal	-5	no	4.979	4.991	EPSD	TCGA;COSMIC;CCLE	4.810	Up-regulation
CAMK_CAMK2_CAMK2A_ST	P35222	CTNNB1	Q9UQM7	CAMK2A	S37	S33T	33	Missense	distal	-4	no	4.979	4.697	EPSD	TCGA;COSMIC	4.810	Loss
CAMK_CAMK2_CAMK2A_ST	P35222	CTNNB1	Q9UQM7	CAMK2A	S37	T41N	41	Missense	distal	4	no	4.979	4.991	EPSD	TCGA;COSMIC	4.810	Up-regulation
CAMK_CAMK2_CAMK2A_ST	P35222	CTNNB1	Q9UQM7	CAMK2A	S37	S37P	37	Missense	central	0	yes	4.979	0.000	EPSD	TCGA;COSMIC;GDSC;CCLE	4.810	Loss
CAMK_CAMK2_CAMK2A_ST	P35222	CTNNB1	Q9UQM7	CAMK2A	S37	D32A	32	Missense	distal	-5	no	4.979	4.934	EPSD	TCGA;COSMIC	4.810	Down-regulation
CAMK_CAMK2_CAMK2A_ST	P35222	CTNNB1	Q9UQM7	CAMK2A	S184	R185G	185	Missense	proximal	1	no	5.549	5.238	EPSD	TCGA;COSMIC	4.810	Down-regulation
CAMK_CAMK2_CAMK2A_ST	P35222	CTNNB1	Q9UQM7	CAMK2A	T332	E334A	334	Missense	proximal	2	no	6.811	5.926	EPSD;PhosphoSitePlus	TCGA;COSMIC	4.810	Down-regulation
CAMK_CAMK2_CAMK2A_ST	P35222	CTNNB1	Q9UQM7	CAMK2A	T332	K335T	335	Missense	distal	3	no	6.811	6.645	EPSD;PhosphoSitePlus	TCGA;COSMIC	4.810	Down-regulation
CAMK_CAMK2_CAMK2A_ST	P35222	CTNNB1	Q9UQM7	CAMK2A	T332	K335I	335	Missense	distal	3	no	6.811	6.595	EPSD;PhosphoSitePlus	TCGA;COSMIC	4.810	Down-regulation
CAMK_CAMK2_CAMK2A_ST	P35222	CTNNB1	Q9UQM7	CAMK2A	T332	Y333F	333	Missense	proximal	1	no	6.811	7.099	EPSD;PhosphoSitePlus	TCGA;COSMIC	4.810	Up-regulation
CAMK_CAMK2_CAMK2A_ST	P35222	CTNNB1	Q9UQM7	CAMK2A	T332	M328I	328	Missense	distal	-4	no	6.811	6.658	EPSD;PhosphoSitePlus	TCGA;COSMIC	4.810	Down-regulation
CAMK_CAMK2_CAMK2A_ST	P35222	CTNNB1	Q9UQM7	CAMK2A	T332	T339N	339	Missense	distal	7	no	6.811	6.763	EPSD;PhosphoSitePlus	TCGA;COSMIC	4.810	Down-regulation
CAMK_CAMK2_CAMK2A_ST	P35222	CTNNB1	Q9UQM7	CAMK2A	T332	E334K	334	Missense	proximal	2	no	6.811	4.769	EPSD;PhosphoSitePlus	TCGA;COSMIC;GDSC;CCLE	4.810	Loss
CAMK_CAMK2_CAMK2A_ST	P35222	CTNNB1	Q9UQM7	CAMK2A	T332	L336P	336	Missense	distal	4	no	6.811	6.848	EPSD;PhosphoSitePlus	TCGA;COSMIC	4.810	Up-regulation
CAMK_CAMK2_CAMK2A_ST	P35222	CTNNB1	Q9UQM7	CAMK2A	T472	R469H	469	Missense	distal	-3	no	6.656	1.158	EPSD;PhosphoSitePlus	TCGA;COSMIC	4.810	Loss
CAMK_CAMK2_CAMK2A_ST	P35222	CTNNB1	Q9UQM7	CAMK2A	T472	R474Q	474	Missense	proximal	2	no	6.656	6.025	EPSD;PhosphoSitePlus	TCGA;GDSC;CCLE	4.810	Down-regulation
CAMK_CAMK2_CAMK2A_ST	P35222	CTNNB1	Q9UQM7	CAMK2A	S552	M553V	553	Missense	proximal	1	no	8.308	8.197	PhosphoSitePlus;EPSD	TCGA;COSMIC	4.810	Down-regulation
CAMK_CAMK2_CAMK2A_ST	P35222	CTNNB1	Q9UQM7	CAMK2A	S675	S681F	681	Missense	distal	6	no	6.091	5.934	EPSD	TCGA	4.810	Down-regulation
CAMK_CAMK2_CAMK2A_ST	O14490	DLGAP1	Q9UQM7	CAMK2A	T76	Q79K	79	Missense	distal	3	no	6.832	6.875	EPSD	TCGA;ICGC;COSMIC	4.810	Up-regulation
CAMK_CAMK2_CAMK2A_ST	O14490	DLGAP1	Q9UQM7	CAMK2A	T76	E80Q	80	Missense	distal	4	no	6.832	6.700	EPSD	TCGA;ICGC;COSMIC	4.810	Down-regulation
CAMK_CAMK2_CAMK2A_ST	O14490	DLGAP1	Q9UQM7	CAMK2A	S134	H130N	130	Missense	distal	-4	no	7.707	7.737	EPSD	TCGA;ICGC;COSMIC	4.810	Up-regulation
CAMK_CAMK2_CAMK2A_ST	O14490	DLGAP1	Q9UQM7	CAMK2A	S134	R131C	131	Missense	distal	-3	no	7.707	2.126	EPSD	TCGA;ICGC;COSMIC	4.810	Loss
CAMK_CAMK2_CAMK2A_ST	O14490	DLGAP1	Q9UQM7	CAMK2A	S134	A127D	127	Missense	distal	-7	no	7.707	8.156	EPSD	TCGA;ICGC	4.810	Up-regulation
CAMK_CAMK2_CAMK2A_ST	O14490	DLGAP1	Q9UQM7	CAMK2A	S233	D229H	229	Missense	distal	-4	no	6.191	6.224	EPSD	TCGA;ICGC;COSMIC	4.810	Up-regulation
CAMK_CAMK2_CAMK2A_ST	O14490	DLGAP1	Q9UQM7	CAMK2A	S233	C227S	227	Missense	distal	-6	no	6.191	6.040	EPSD	TCGA;ICGC;COSMIC	4.810	Down-regulation
CAMK_CAMK2_CAMK2A_ST	O14490	DLGAP1	Q9UQM7	CAMK2A	S233	P228L	228	Missense	distal	-5	no	6.191	6.098	EPSD	TCGA;ICGC;COSMIC	4.810	Down-regulation
CAMK_CAMK2_CAMK2A_ST	O14490	DLGAP1	Q9UQM7	CAMK2A	S233	R230C	230	Missense	distal	-3	no	6.191	0.610	EPSD	TCGA;ICGC;COSMIC	4.810	Loss
CAMK_CAMK2_CAMK2A_ST	O14490	DLGAP1	Q9UQM7	CAMK2A	S346	I348M	348	Missense	proximal	2	no	6.665	6.834	EPSD	TCGA;COSMIC	4.810	Up-regulation
CAMK_CAMK2_CAMK2A_ST	O14490	DLGAP1	Q9UQM7	CAMK2A	S346	A350V	350	Missense	distal	4	no	6.665	6.611	EPSD	TCGA;COSMIC	4.810	Down-regulation
CAMK_CAMK2_CAMK2A_ST	O14490	DLGAP1	Q9UQM7	CAMK2A	S375	R373K	373	Missense	proximal	-2	no	7.065	7.241	EPSD	TCGA;COSMIC	4.810	Up-regulation
CAMK_CAMK2_CAMK2A_ST	O14490	DLGAP1	Q9UQM7	CAMK2A	S375	R372Q	372	Missense	distal	-3	no	7.065	3.493	EPSD	TCGA;COSMIC	4.810	Loss
CAMK_CAMK2_CAMK2A_ST	O14490	DLGAP1	Q9UQM7	CAMK2A	S375	Q381E	381	Missense	distal	6	no	7.065	7.076	EPSD	TCGA;COSMIC	4.810	Up-regulation
CAMK_CAMK2_CAMK2A_ST	O14490	DLGAP1	Q9UQM7	CAMK2A	S406	H405N	405	Missense	proximal	-1	no	6.305	6.112	EPSD	TCGA	4.810	Down-regulation
CAMK_CAMK2_CAMK2A_ST	O14490	DLGAP1	Q9UQM7	CAMK2A	S412	S415P	415	Missense	distal	3	no	5.527	5.255	EPSD	TCGA;COSMIC	4.810	Down-regulation
CAMK_CAMK2_CAMK2A_ST	O14490	DLGAP1	Q9UQM7	CAMK2A	S412	R418Q	418	Missense	distal	6	no	5.527	5.533	EPSD	TCGA;COSMIC	4.810	Up-regulation
CAMK_CAMK2_CAMK2A_ST	O14490	DLGAP1	Q9UQM7	CAMK2A	S412	R418W	418	Missense	distal	6	no	5.527	5.288	EPSD	TCGA	4.810	Down-regulation
CAMK_CAMK2_CAMK2A_ST	O14490	DLGAP1	Q9UQM7	CAMK2A	S412	H405N	405	Missense	distal	-7	no	5.527	5.716	EPSD	TCGA	4.810	Up-regulation
CAMK_CAMK2_CAMK2A_ST	O14490	DLGAP1	Q9UQM7	CAMK2A	S419	P425S	425	Missense	distal	6	no	6.360	6.443	EPSD	TCGA;COSMIC	4.810	Up-regulation
CAMK_CAMK2_CAMK2A_ST	O14490	DLGAP1	Q9UQM7	CAMK2A	S419	A426E	426	Missense	distal	7	no	6.360	6.170	EPSD	TCGA;COSMIC	4.810	Down-regulation
CAMK_CAMK2_CAMK2A_ST	O14490	DLGAP1	Q9UQM7	CAMK2A	S419	D424N	424	Missense	distal	5	no	6.360	6.371	EPSD	TCGA;COSMIC	4.810	Up-regulation
CAMK_CAMK2_CAMK2A_ST	O14490	DLGAP1	Q9UQM7	CAMK2A	S419	S415P	415	Missense	distal	-4	no	6.360	5.981	EPSD	TCGA;COSMIC	4.810	Down-regulation
CAMK_CAMK2_CAMK2A_ST	O14490	DLGAP1	Q9UQM7	CAMK2A	S419	R418Q	418	Missense	proximal	-1	no	6.360	6.604	EPSD	TCGA;COSMIC	4.810	Up-regulation
CAMK_CAMK2_CAMK2A_ST	O14490	DLGAP1	Q9UQM7	CAMK2A	S419	R418W	418	Missense	proximal	-1	no	6.360	5.777	EPSD	TCGA	4.810	Down-regulation
CAMK_CAMK2_CAMK2A_ST	O14490	DLGAP1	Q9UQM7	CAMK2A	S491	R488H	488	Missense	distal	-3	no	7.188	1.690	EPSD	TCGA;COSMIC	4.810	Loss
CAMK_CAMK2_CAMK2A_ST	O14490	DLGAP1	Q9UQM7	CAMK2A	S491	R488C	488	Missense	distal	-3	no	7.188	1.607	EPSD	TCGA;COSMIC	4.810	Loss
CAMK_CAMK2_CAMK2A_ST	O14490	DLGAP1	Q9UQM7	CAMK2A	S491	R490W	490	Missense	proximal	-1	no	7.188	6.605	EPSD	TCGA	4.810	Down-regulation
CAMK_CAMK2_CAMK2A_ST	O14490	DLGAP1	Q9UQM7	CAMK2A	S493	R488H	488	Missense	distal	-5	no	7.165	7.110	EPSD	TCGA;COSMIC	4.810	Down-regulation
CAMK_CAMK2_CAMK2A_ST	O14490	DLGAP1	Q9UQM7	CAMK2A	S493	R488C	488	Missense	distal	-5	no	7.165	7.163	EPSD	TCGA;COSMIC	4.810	Down-regulation
CAMK_CAMK2_CAMK2A_ST	O14490	DLGAP1	Q9UQM7	CAMK2A	S493	R490W	490	Missense	distal	-3	no	7.165	-4.856	EPSD	TCGA	4.810	Loss
CAMK_CAMK2_CAMK2A_ST	O14490	DLGAP1	Q9UQM7	CAMK2A	S503	D506N	506	Missense	distal	3	no	5.870	5.742	EPSD	TCGA;COSMIC	4.810	Down-regulation
CAMK_CAMK2_CAMK2A_ST	O14490	DLGAP1	Q9UQM7	CAMK2A	S503	S510P	510	Missense	distal	7	no	5.870	5.968	EPSD	TCGA;COSMIC	4.810	Up-regulation
CAMK_CAMK2_CAMK2A_ST	O14490	DLGAP1	Q9UQM7	CAMK2A	S515	P516L	516	Missense	proximal	1	no	7.871	8.529	EPSD	TCGA;COSMIC	4.810	Up-regulation
CAMK_CAMK2_CAMK2A_ST	O14490	DLGAP1	Q9UQM7	CAMK2A	S515	S513L	513	Missense	proximal	-2	no	7.871	7.768	EPSD	TCGA;COSMIC	4.810	Down-regulation
CAMK_CAMK2_CAMK2A_ST	O14490	DLGAP1	Q9UQM7	CAMK2A	S515	L511M	511	Missense	distal	-4	no	7.871	7.943	EPSD	TCGA;COSMIC	4.810	Up-regulation
CAMK_CAMK2_CAMK2A_ST	O14490	DLGAP1	Q9UQM7	CAMK2A	S515	S510P	510	Missense	distal	-5	no	7.871	7.872	EPSD	TCGA;COSMIC	4.810	Up-regulation
CAMK_CAMK2_CAMK2A_ST	O14490	DLGAP1	Q9UQM7	CAMK2A	S515	P517L	517	Missense	proximal	2	no	7.871	8.035	EPSD	TCGA;COSMIC	4.810	Up-regulation
CAMK_CAMK2_CAMK2A_ST	O14490	DLGAP1	Q9UQM7	CAMK2A	S515	S515L	515	Missense	central	0	yes	7.871	0.000	EPSD	TCGA;COSMIC	4.810	Loss
CAMK_CAMK2_CAMK2A_ST	O14490	DLGAP1	Q9UQM7	CAMK2A	S562	Q567H	567	Missense	distal	5	no	5.265	5.380	EPSD	TCGA;COSMIC	4.810	Up-regulation
CAMK_CAMK2_CAMK2A_ST	O14490	DLGAP1	Q9UQM7	CAMK2A	T590	S587R	587	Missense	distal	-3	no	1.614	6.075	EPSD	TCGA;COSMIC	4.810	Gain
CAMK_CAMK2_CAMK2A_ST	O14490	DLGAP1	Q9UQM7	CAMK2A	S592	S587R	587	Missense	distal	-5	no	5.179	5.108	EPSD	TCGA;COSMIC	4.810	Down-regulation
CAMK_CAMK2_CAMK2A_ST	O14490	DLGAP1	Q9UQM7	CAMK2A	S592	L593M	593	Missense	proximal	1	no	5.179	5.133	EPSD	TCGA	4.810	Down-regulation
CAMK_CAMK2_CAMK2A_ST	O14490	DLGAP1	Q9UQM7	CAMK2A	S592	S587G	587	Missense	distal	-5	no	5.179	5.215	EPSD	TCGA;COSMIC	4.810	Up-regulation
CAMK_CAMK2_CAMK2A_ST	O14490	DLGAP1	Q9UQM7	CAMK2A	S651	I652F	652	Missense	proximal	1	no	9.541	9.384	EPSD	TCGA;COSMIC	4.810	Down-regulation
CAMK_CAMK2_CAMK2A_ST	O14490	DLGAP1	Q9UQM7	CAMK2A	S695	R692Q	692	Missense	distal	-3	no	8.269	4.697	EPSD	TCGA;COSMIC	4.810	Loss
CAMK_CAMK2_CAMK2A_ST	O14490	DLGAP1	Q9UQM7	CAMK2A	S958	T960I	960	Missense	proximal	2	no	8.147	8.703	EPSD	TCGA;COSMIC	4.810	Up-regulation
CAMK_CAMK2_CAMK2A_ST	O14490	DLGAP1	Q9UQM7	CAMK2A	S958	E964K	964	Missense	distal	6	no	8.147	8.095	EPSD	TCGA;COSMIC	4.810	Down-regulation
CAMK_CAMK2_CAMK2A_ST	O14490	DLGAP1	Q9UQM7	CAMK2A	S958	T960N	960	Missense	proximal	2	no	8.147	9.603	EPSD	TCGA;COSMIC	4.810	Up-regulation
CAMK_CAMK2_CAMK2A_ST	O14490	DLGAP1	Q9UQM7	CAMK2A	S962	T960I	960	Missense	proximal	-2	no	6.538	6.513	EPSD	TCGA;COSMIC	4.810	Down-regulation
CAMK_CAMK2_CAMK2A_ST	O14490	DLGAP1	Q9UQM7	CAMK2A	S962	E964K	964	Missense	proximal	2	no	6.538	4.497	EPSD	TCGA;COSMIC	4.810	Loss
CAMK_CAMK2_CAMK2A_ST	O14490	DLGAP1	Q9UQM7	CAMK2A	S962	T960N	960	Missense	proximal	-2	no	6.538	6.731	EPSD	TCGA;COSMIC	4.810	Up-regulation
CAMK_CAMK2_CAMK2A_ST	P09917	ALOX5	Q9UQM7	CAMK2A	T105	P99S	99	Missense	distal	-6	no	6.840	6.791	EPSD	TCGA;ICGC;COSMIC	4.810	Down-regulation
CAMK_CAMK2_CAMK2A_ST	P09917	ALOX5	Q9UQM7	CAMK2A	T105	E109K	109	Missense	distal	4	no	6.840	6.664	EPSD	TCGA;ICGC;COSMIC	4.810	Down-regulation
CAMK_CAMK2_CAMK2A_ST	P09917	ALOX5	Q9UQM7	CAMK2A	T105	D107N	107	Missense	proximal	2	no	6.840	5.829	EPSD	TCGA;ICGC;COSMIC	4.810	Down-regulation
CAMK_CAMK2_CAMK2A_ST	P09917	ALOX5	Q9UQM7	CAMK2A	T105	R102H	102	Missense	distal	-3	no	6.840	1.343	EPSD	TCGA;ICGC	4.810	Loss
CAMK_CAMK2_CAMK2A_ST	P09917	ALOX5	Q9UQM7	CAMK2A	S272	E274D	274	Missense	proximal	2	no	11.464	12.381	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	4.810	Up-regulation
CAMK_CAMK2_CAMK2A_ST	P09917	ALOX5	Q9UQM7	CAMK2A	T486	E488K	488	Missense	proximal	2	no	6.904	4.863	EPSD	TCGA;ICGC;COSMIC;CCLE	4.810	Down-regulation
CAMK_CAMK2_CAMK2A_ST	P09917	ALOX5	Q9UQM7	CAMK2A	S524	R521H	521	Missense	distal	-3	no	6.284	0.787	EPSD	TCGA;ICGC;COSMIC	4.810	Loss
CAMK_CAMK2_CAMK2A_ST	P09917	ALOX5	Q9UQM7	CAMK2A	S524	S529L	529	Missense	distal	5	no	6.284	5.995	EPSD	TCGA;ICGC;COSMIC	4.810	Down-regulation
CAMK_CAMK2_CAMK2A_ST	P09917	ALOX5	Q9UQM7	CAMK2A	S524	R521C	521	Missense	distal	-3	no	6.284	0.703	EPSD	TCGA;ICGC;COSMIC	4.810	Loss
CAMK_CAMK2_CAMK2A_ST	P09917	ALOX5	Q9UQM7	CAMK2A	S524	R519W	519	Missense	distal	-5	no	6.284	6.432	EPSD	TCGA;ICGC;COSMIC	4.810	Up-regulation
CAMK_CAMK2_CAMK2A_ST	P09917	ALOX5	Q9UQM7	CAMK2A	S532	R533W	533	Missense	proximal	1	no	5.900	5.610	EPSD	TCGA;ICGC;COSMIC	4.810	Down-regulation
CAMK_CAMK2_CAMK2A_ST	P09917	ALOX5	Q9UQM7	CAMK2A	S532	L536P	536	Missense	distal	4	no	5.900	5.937	EPSD	TCGA;ICGC;COSMIC	4.810	Up-regulation
CAMK_CAMK2_CAMK2A_ST	P09917	ALOX5	Q9UQM7	CAMK2A	S532	S529L	529	Missense	distal	-3	no	5.900	5.238	EPSD	TCGA;ICGC;COSMIC	4.810	Down-regulation
CAMK_CAMK2_CAMK2A_ST	P41134	ID1	Q9UQM7	CAMK2A	S36	E30K	30	Missense	distal	-6	no	5.316	5.417	PhosphoSitePlus	TCGA;ICGC;COSMIC	4.810	Up-regulation
CAMK_CAMK2_CAMK2A_ST	P41134	ID1	Q9UQM7	CAMK2A	S36	L35V	35	Missense	proximal	-1	no	5.316	5.357	PhosphoSitePlus	TCGA;ICGC;COSMIC	4.810	Up-regulation
CAMK_CAMK2_CAMK2A_ST	P55055	NR1H2	Q9UQM7	CAMK2A	S426	M422T	422	Missense	distal	-4	no	6.813	6.757	PhosphoSitePlus	TCGA;ICGC	4.810	Down-regulation
CAMK_CAMK2_CAMK2A_ST	P55055	NR1H2	Q9UQM7	CAMK2A	S426	S432Y	432	Missense	distal	6	no	6.813	6.705	PhosphoSitePlus	TCGA;ICGC;COSMIC	4.810	Down-regulation
CAMK_CAMK2_CAMK2A_ST	P51790	CLCN3	Q9UQM7	CAMK2A	S109	W116L	116	Missense	distal	7	no	8.332	8.076	PhosphoSitePlus	TCGA;ICGC;COSMIC	4.810	Down-regulation
CAMK_CAMK2_CAMK2A_ST	P51790	CLCN3	Q9UQM7	CAMK2A	T713	R720S	720	Missense	distal	7	no	5.856	5.752	EPSD	TCGA;ICGC;COSMIC	4.810	Down-regulation
CAMK_CAMK2_CAMK2A_ST	P51790	CLCN3	Q9UQM7	CAMK2A	T713	L708I	708	Missense	distal	-5	no	5.856	5.746	EPSD	TCGA;ICGC	4.810	Down-regulation
CAMK_CAMK2_CAMK2A_ST	P40189	IL6ST	Q9UQM7	CAMK2A	S238	E235K	235	Missense	distal	-3	no	2.346	5.196	EPSD	TCGA;ICGC;COSMIC	4.810	Gain
CAMK_CAMK2_CAMK2A_ST	P40189	IL6ST	Q9UQM7	CAMK2A	S782	S782C	782	Missense	central	0	yes	8.741	0.000	PhosphoSitePlus	TCGA;ICGC;COSMIC	4.810	Loss
CAMK_CAMK2_CAMK2A_ST	P40189	IL6ST	Q9UQM7	CAMK2A	S782	R779I	779	Missense	distal	-3	no	8.741	4.470	PhosphoSitePlus	TCGA;COSMIC	4.810	Loss
CAMK_CAMK2_CAMK2A_ST	P40189	IL6ST	Q9UQM7	CAMK2A	S838	F845C	845	Missense	distal	7	no	5.694	5.708	EPSD	TCGA;ICGC;COSMIC	4.810	Up-regulation
CAMK_CAMK2_CAMK2A_ST	P40189	IL6ST	Q9UQM7	CAMK2A	S838	S838L	838	Missense	central	0	yes	5.694	0.000	EPSD	TCGA;COSMIC	4.810	Loss
CAMK_CAMK2_CAMK2A_ST	Q00613	HSF1	Q9UQM7	CAMK2A	T120	L125M	125	Missense	distal	5	no	7.050	7.164	EPSD	TCGA;COSMIC	4.810	Up-regulation
CAMK_CAMK2_CAMK2A_ST	Q00613	HSF1	Q9UQM7	CAMK2A	S121	E128K	128	Missense	distal	7	no	5.278	5.488	EPSD	TCGA;COSMIC	4.810	Up-regulation
CAMK_CAMK2_CAMK2A_ST	Q00613	HSF1	Q9UQM7	CAMK2A	S121	L125M	125	Missense	distal	4	no	5.278	5.361	EPSD	TCGA;COSMIC	4.810	Up-regulation
CAMK_CAMK2_CAMK2A_ST	Q00613	HSF1	Q9UQM7	CAMK2A	S127	E128K	128	Missense	proximal	1	no	6.289	6.034	EPSD	TCGA;COSMIC	4.810	Down-regulation
CAMK_CAMK2_CAMK2A_ST	Q00613	HSF1	Q9UQM7	CAMK2A	S127	R133H	133	Missense	distal	6	no	6.289	6.263	EPSD	TCGA;COSMIC	4.810	Down-regulation
CAMK_CAMK2_CAMK2A_ST	Q00613	HSF1	Q9UQM7	CAMK2A	S127	I130V	130	Missense	distal	3	no	6.289	6.512	EPSD	TCGA;COSMIC	4.810	Up-regulation
CAMK_CAMK2_CAMK2A_ST	Q00613	HSF1	Q9UQM7	CAMK2A	S127	L125M	125	Missense	proximal	-2	no	6.289	6.575	EPSD	TCGA;COSMIC	4.810	Up-regulation
CAMK_CAMK2_CAMK2A_ST	Q00613	HSF1	Q9UQM7	CAMK2A	S136	R133H	133	Missense	distal	-3	no	8.581	3.084	EPSD	TCGA;COSMIC	4.810	Loss
CAMK_CAMK2_CAMK2A_ST	Q00613	HSF1	Q9UQM7	CAMK2A	S136	I130V	130	Missense	distal	-6	no	8.581	8.646	EPSD	TCGA;COSMIC	4.810	Up-regulation
CAMK_CAMK2_CAMK2A_ST	Q00613	HSF1	Q9UQM7	CAMK2A	S283	P288L	288	Missense	distal	5	no	6.199	6.140	EPSD	TCGA;COSMIC	4.810	Down-regulation
CAMK_CAMK2_CAMK2A_ST	Q00613	HSF1	Q9UQM7	CAMK2A	S283	P276L	276	Missense	distal	-7	no	6.199	6.165	EPSD	TCGA;COSMIC	4.810	Down-regulation
CAMK_CAMK2_CAMK2A_ST	Q00613	HSF1	Q9UQM7	CAMK2A	S283	E286K	286	Missense	distal	3	no	6.199	6.034	EPSD	TCGA;COSMIC	4.810	Down-regulation
CAMK_CAMK2_CAMK2A_ST	Q00613	HSF1	Q9UQM7	CAMK2A	S283	M277V	277	Missense	distal	-6	no	6.199	6.321	EPSD	TCGA;COSMIC	4.810	Up-regulation
CAMK_CAMK2_CAMK2A_ST	Q00613	HSF1	Q9UQM7	CAMK2A	S290	R296C	296	Missense	distal	6	no	6.695	6.530	EPSD	TCGA;COSMIC	4.810	Down-regulation
CAMK_CAMK2_CAMK2A_ST	Q00613	HSF1	Q9UQM7	CAMK2A	S290	P288L	288	Missense	proximal	-2	no	6.695	6.585	EPSD	TCGA;COSMIC	4.810	Down-regulation
CAMK_CAMK2_CAMK2A_ST	Q00613	HSF1	Q9UQM7	CAMK2A	S290	E286K	286	Missense	distal	-4	no	6.695	6.647	EPSD	TCGA;COSMIC	4.810	Down-regulation
CAMK_CAMK2_CAMK2A_ST	Q00613	HSF1	Q9UQM7	CAMK2A	S320	R317H	317	Missense	distal	-3	no	9.417	3.920	EPSD	TCGA;COSMIC	4.810	Loss
CAMK_CAMK2_CAMK2A_ST	Q00613	HSF1	Q9UQM7	CAMK2A	S320	T323I	323	Missense	distal	3	no	9.417	9.367	EPSD	TCGA;COSMIC	4.810	Down-regulation
CAMK_CAMK2_CAMK2A_ST	Q00613	HSF1	Q9UQM7	CAMK2A	S320	S320F	320	Missense	central	0	yes	9.417	0.000	EPSD	TCGA;COSMIC	4.810	Loss
CAMK_CAMK2_CAMK2A_ST	Q00613	HSF1	Q9UQM7	CAMK2A	S320	P327L	327	Missense	distal	7	no	9.417	9.482	EPSD	TCGA	4.810	Up-regulation
CAMK_CAMK2_CAMK2A_ST	Q00613	HSF1	Q9UQM7	CAMK2A	T355	A351T	351	Missense	distal	-4	no	6.031	5.741	EPSD	TCGA;COSMIC	4.810	Down-regulation
CAMK_CAMK2_CAMK2A_ST	Q00613	HSF1	Q9UQM7	CAMK2A	S363	P364S	364	Missense	proximal	1	no	6.498	6.865	EPSD	TCGA;COSMIC	4.810	Up-regulation
CAMK_CAMK2_CAMK2A_ST	Q00613	HSF1	Q9UQM7	CAMK2A	S458	E453K	453	Missense	distal	-5	no	4.973	4.970	EPSD	TCGA;COSMIC	4.810	Down-regulation
CAMK_CAMK2_CAMK2A_ST	Q4G163	FBXO43	Q9UQM7	CAMK2A	T234	K231N	231	Missense	distal	-3	no	6.441	3.875	PhosphoSitePlus	TCGA;ICGC;COSMIC	4.810	Loss
CAMK_CAMK2_CAMK2A_ST	Q4G163	FBXO43	Q9UQM7	CAMK2A	S385	R388W	388	Missense	distal	3	no	6.448	5.896	EPSD	TCGA;ICGC;COSMIC;CCLE	4.810	Down-regulation
CAMK_CAMK2_CAMK2A_ST	Q4G163	FBXO43	Q9UQM7	CAMK2A	S385	S391C	391	Missense	distal	6	no	6.448	6.284	EPSD	TCGA;ICGC;COSMIC	4.810	Down-regulation
CAMK_CAMK2_CAMK2A_ST	Q4G163	FBXO43	Q9UQM7	CAMK2A	S385	Q390L	390	Missense	distal	5	no	6.448	6.301	EPSD	TCGA;ICGC;COSMIC	4.810	Down-regulation
CAMK_CAMK2_CAMK2A_ST	Q4G163	FBXO43	Q9UQM7	CAMK2A	S698	R703Q	703	Missense	distal	5	no	4.896	4.895	EPSD	TCGA;ICGC;COSMIC	4.810	Down-regulation
CAMK_CAMK2_CAMK2A_ST	Q4G163	FBXO43	Q9UQM7	CAMK2A	S698	P696L	696	Missense	proximal	-2	no	4.896	4.786	EPSD	TCGA;ICGC;COSMIC	4.810	Loss
CAMK_CAMK2_CAMK2A_ST	Q4G163	FBXO43	Q9UQM7	CAMK2A	S698	P696S	696	Missense	proximal	-2	no	4.896	4.889	EPSD	TCGA;ICGC;COSMIC	4.810	Down-regulation
CAMK_CAMK2_CAMK2A_ST	P55042	RRAD	Q9UQM7	CAMK2A	S214	V215G	215	Missense	proximal	1	no	11.533	10.901	EPSD	TCGA;ICGC;COSMIC	4.810	Down-regulation
CAMK_CAMK2_CAMK2A_ST	P55042	RRAD	Q9UQM7	CAMK2A	S214	V215A	215	Missense	proximal	1	no	11.533	11.182	EPSD	TCGA;ICGC;COSMIC	4.810	Down-regulation
CAMK_CAMK2_CAMK2A_ST	P55042	RRAD	Q9UQM7	CAMK2A	S257	R252L	252	Missense	distal	-5	no	7.537	7.517	EPSD	TCGA;ICGC;COSMIC	4.810	Down-regulation
CAMK_CAMK2_CAMK2A_ST	P55042	RRAD	Q9UQM7	CAMK2A	S257	R254H	254	Missense	distal	-3	no	7.537	2.040	EPSD	TCGA;ICGC;COSMIC	4.810	Loss
CAMK_CAMK2_CAMK2A_ST	P55042	RRAD	Q9UQM7	CAMK2A	S257	E259K	259	Missense	proximal	2	no	7.537	5.496	EPSD	TCGA;ICGC;COSMIC	4.810	Down-regulation
CAMK_CAMK2_CAMK2A_ST	P55042	RRAD	Q9UQM7	CAMK2A	S257	R263Q	263	Missense	distal	6	no	7.537	7.543	EPSD	TCGA;ICGC;COSMIC	4.810	Up-regulation
CAMK_CAMK2_CAMK2A_ST	P55042	RRAD	Q9UQM7	CAMK2A	S257	R264Q	264	Missense	distal	7	no	7.537	7.418	EPSD	TCGA;ICGC;COSMIC	4.810	Down-regulation
CAMK_CAMK2_CAMK2A_ST	P55042	RRAD	Q9UQM7	CAMK2A	S273	R271Q	271	Missense	proximal	-2	no	8.905	9.122	PhosphoSitePlus	TCGA;ICGC;COSMIC	4.810	Up-regulation
CAMK_CAMK2_CAMK2A_ST	P55042	RRAD	Q9UQM7	CAMK2A	S273	R280H	280	Missense	distal	7	no	8.905	8.857	PhosphoSitePlus	TCGA;ICGC;COSMIC	4.810	Down-regulation
CAMK_CAMK2_CAMK2A_ST	P55042	RRAD	Q9UQM7	CAMK2A	S273	E272D	272	Missense	proximal	-1	no	8.905	8.481	PhosphoSitePlus	TCGA;ICGC	4.810	Down-regulation
CAMK_CAMK2_CAMK2A_ST	P55042	RRAD	Q9UQM7	CAMK2A	S273	R269Q	269	Missense	distal	-4	no	8.905	8.800	PhosphoSitePlus	TCGA;ICGC;COSMIC	4.810	Down-regulation
CAMK_CAMK2_CAMK2A_ST	P55042	RRAD	Q9UQM7	CAMK2A	S273	K279R	279	Missense	distal	6	no	8.905	8.938	PhosphoSitePlus	TCGA;ICGC;COSMIC	4.810	Up-regulation
CAMK_CAMK2_CAMK2A_ST	P55042	RRAD	Q9UQM7	CAMK2A	S273	K277R	277	Missense	distal	4	no	8.905	8.780	PhosphoSitePlus	TCGA	4.810	Down-regulation
CAMK_CAMK2_CAMK2A_ST	P55042	RRAD	Q9UQM7	CAMK2A	S299	R296C	296	Missense	distal	-3	no	8.617	3.036	EPSD	TCGA;ICGC;COSMIC	4.810	Loss
CAMK_CAMK2_CAMK2A_ST	P55042	RRAD	Q9UQM7	CAMK2A	S299	S301F	301	Missense	proximal	2	no	8.617	7.366	EPSD	TCGA;ICGC;COSMIC	4.810	Down-regulation
CAMK_CAMK2_CAMK2A_ST	P55042	RRAD	Q9UQM7	CAMK2A	S299	D304N	304	Missense	distal	5	no	8.617	8.628	EPSD	TCGA;ICGC;COSMIC;CCLE	4.810	Up-regulation
CAMK_CAMK2_CAMK2A_ST	P55042	RRAD	Q9UQM7	CAMK2A	S301	R296C	296	Missense	distal	-5	no	6.107	6.106	EPSD	TCGA;ICGC;COSMIC	4.810	Down-regulation
CAMK_CAMK2_CAMK2A_ST	P55042	RRAD	Q9UQM7	CAMK2A	S301	S301F	301	Missense	central	0	yes	6.107	0.000	EPSD	TCGA;ICGC;COSMIC	4.810	Loss
CAMK_CAMK2_CAMK2A_ST	P55042	RRAD	Q9UQM7	CAMK2A	S301	D304N	304	Missense	distal	3	no	6.107	5.980	EPSD	TCGA;ICGC;COSMIC;CCLE	4.810	Down-regulation
CAMK_CAMK2_CAMK2A_ST	Q96PM5	RCHY1	Q9UQM7	CAMK2A	S257	R254H	254	Missense	distal	-3	no	8.323	2.826	EPSD	TCGA;ICGC;COSMIC;GDSC;CCLE	4.810	Loss
CAMK_CAMK2_CAMK2A_ST	P16949	STMN1	Q9UQM7	CAMK2A	S63	E58D	58	Missense	distal	-5	no	9.684	9.848	EPSD	TCGA;ICGC;COSMIC	4.810	Up-regulation
CAMK_CAMK2_CAMK2A_ST	P16949	STMN1	Q9UQM7	CAMK2A	S63	A66G	66	Missense	distal	3	no	9.684	9.493	EPSD	TCGA;ICGC;COSMIC	4.810	Down-regulation
CAMK_CAMK2_CAMK2A_ST	P16949	STMN1	Q9UQM7	CAMK2A	S63	R61H	61	Missense	proximal	-2	no	9.684	9.563	EPSD	TCGA;ICGC;COSMIC	4.810	Down-regulation
CAMK_CAMK2_CAMK2A_ST	P16949	STMN1	Q9UQM7	CAMK2A	S63	S63P	63	Missense	central	0	yes	9.684	0.000	EPSD	TCGA;ICGC;COSMIC	4.810	Loss
CAMK_CAMK2_CAMK2A_ST	Q9Y496	KIF3A	Q9UQM7	CAMK2A	S30	A36D	36	Missense	distal	6	no	9.191	9.178	EPSD	TCGA;ICGC;COSMIC	4.810	Down-regulation
CAMK_CAMK2_CAMK2A_ST	Q9Y496	KIF3A	Q9UQM7	CAMK2A	S38	A36D	36	Missense	proximal	-2	no	7.387	6.998	EPSD	TCGA;ICGC;COSMIC	4.810	Down-regulation
CAMK_CAMK2_CAMK2A_ST	Q9Y496	KIF3A	Q9UQM7	CAMK2A	S207	T200M	200	Missense	distal	-7	no	6.388	6.258	EPSD	TCGA;ICGC;COSMIC	4.810	Down-regulation
CAMK_CAMK2_CAMK2A_ST	Q9Y496	KIF3A	Q9UQM7	CAMK2A	S207	R206C	206	Missense	proximal	-1	no	6.388	6.060	EPSD	TCGA;ICGC;COSMIC	4.810	Down-regulation
CAMK_CAMK2_CAMK2A_ST	Q9Y496	KIF3A	Q9UQM7	CAMK2A	S217	E215K	215	Missense	proximal	-2	no	4.684	4.908	EPSD	TCGA;ICGC;COSMIC	4.810	Gain
CAMK_CAMK2_CAMK2A_ST	Q9Y496	KIF3A	Q9UQM7	CAMK2A	S415	R408I	408	Missense	distal	-7	no	6.907	7.113	EPSD	TCGA;ICGC;COSMIC	4.810	Up-regulation
CAMK_CAMK2_CAMK2A_ST	Q9Y496	KIF3A	Q9UQM7	CAMK2A	S415	K412N	412	Missense	distal	-3	no	6.907	4.340	EPSD	TCGA;ICGC	4.810	Loss
CAMK_CAMK2_CAMK2A_ST	Q9Y496	KIF3A	Q9UQM7	CAMK2A	S415	R409K	409	Missense	distal	-6	no	6.907	6.935	EPSD	TCGA	4.810	Up-regulation
CAMK_CAMK2_CAMK2A_ST	Q9Y496	KIF3A	Q9UQM7	CAMK2A	S534	E537D	537	Missense	distal	3	no	6.134	6.011	EPSD	TCGA;ICGC;COSMIC	4.810	Down-regulation
CAMK_CAMK2_CAMK2A_ST	Q9Y496	KIF3A	Q9UQM7	CAMK2A	S534	K531Q	531	Missense	distal	-3	no	6.134	4.830	EPSD	TCGA;ICGC;COSMIC	4.810	Down-regulation
CAMK_CAMK2_CAMK2A_ST	Q9Y496	KIF3A	Q9UQM7	CAMK2A	T633	E640D	640	Missense	distal	7	no	6.443	6.651	EPSD	TCGA	4.810	Up-regulation
CAMK_CAMK2_CAMK2A_ST	Q9Y496	KIF3A	Q9UQM7	CAMK2A	T633	V635I	635	Missense	proximal	2	no	6.443	6.347	EPSD	TCGA;ICGC;COSMIC	4.810	Down-regulation
CAMK_CAMK2_CAMK2A_ST	Q9Y496	KIF3A	Q9UQM7	CAMK2A	T633	M629T	629	Missense	distal	-4	no	6.443	6.386	EPSD	TCGA;ICGC;COSMIC	4.810	Down-regulation
CAMK_CAMK2_CAMK2A_ST	Q9Y496	KIF3A	Q9UQM7	CAMK2A	S687	R686C	686	Missense	proximal	-1	no	9.452	9.123	PhosphoSitePlus	TCGA;ICGC;COSMIC	4.810	Down-regulation
CAMK_CAMK2_CAMK2A_ST	Q9Y4D2	DAGLA	Q9UQM7	CAMK2A	S727	S725G	725	Missense	proximal	-2	no	5.801	5.643	EPSD	TCGA;ICGC;COSMIC	4.810	Down-regulation
CAMK_CAMK2_CAMK2A_ST	Q9Y4D2	DAGLA	Q9UQM7	CAMK2A	S729	S725G	725	Missense	distal	-4	no	7.741	7.464	EPSD	TCGA;ICGC;COSMIC	4.810	Down-regulation
CAMK_CAMK2_CAMK2A_ST	Q9Y4D2	DAGLA	Q9UQM7	CAMK2A	S732	S725G	725	Missense	distal	-7	no	5.124	5.423	EPSD	TCGA;ICGC;COSMIC	4.810	Up-regulation
CAMK_CAMK2_CAMK2A_ST	Q9Y4D2	DAGLA	Q9UQM7	CAMK2A	S743	R740Q	740	Missense	distal	-3	no	5.894	2.323	EPSD	TCGA;ICGC;COSMIC	4.810	Loss
CAMK_CAMK2_CAMK2A_ST	Q9Y4D2	DAGLA	Q9UQM7	CAMK2A	S743	R740W	740	Missense	distal	-3	no	5.894	-6.126	EPSD	TCGA;ICGC;COSMIC	4.810	Loss
CAMK_CAMK2_CAMK2A_ST	Q9Y4D2	DAGLA	Q9UQM7	CAMK2A	S798	R795H	795	Missense	distal	-3	no	6.335	0.838	EPSD	TCGA;ICGC;COSMIC	4.810	Loss
CAMK_CAMK2_CAMK2A_ST	Q9Y4D2	DAGLA	Q9UQM7	CAMK2A	S798	S791C	791	Missense	distal	-7	no	6.335	6.971	EPSD	TCGA;ICGC;COSMIC	4.810	Up-regulation
CAMK_CAMK2_CAMK2A_ST	Q9Y4D2	DAGLA	Q9UQM7	CAMK2A	S798	R804W	804	Missense	distal	6	no	6.335	6.097	EPSD	TCGA;ICGC;COSMIC	4.810	Down-regulation
CAMK_CAMK2_CAMK2A_ST	Q9Y4D2	DAGLA	Q9UQM7	CAMK2A	S850	D844N	844	Missense	distal	-6	no	5.879	5.902	EPSD	TCGA;ICGC;COSMIC	4.810	Up-regulation
CAMK_CAMK2_CAMK2A_ST	Q9Y4D2	DAGLA	Q9UQM7	CAMK2A	S850	P855L	855	Missense	distal	5	no	5.879	5.820	EPSD	TCGA;ICGC;COSMIC	4.810	Down-regulation
CAMK_CAMK2_CAMK2A_ST	Q9Y4D2	DAGLA	Q9UQM7	CAMK2A	S872	R869P	869	Missense	distal	-3	no	7.599	2.682	EPSD	TCGA;ICGC;COSMIC	4.810	Loss
CAMK_CAMK2_CAMK2A_ST	Q9Y4D2	DAGLA	Q9UQM7	CAMK2A	S872	E878K	878	Missense	distal	6	no	7.599	7.548	EPSD	TCGA;ICGC;COSMIC	4.810	Down-regulation
CAMK_CAMK2_CAMK2A_ST	Q9Y4D2	DAGLA	Q9UQM7	CAMK2A	S872	V865I	865	Missense	distal	-7	no	7.599	7.571	EPSD	TCGA;ICGC;COSMIC	4.810	Down-regulation
CAMK_CAMK2_CAMK2A_ST	Q9Y4D2	DAGLA	Q9UQM7	CAMK2A	S872	P870L	870	Missense	proximal	-2	no	7.599	7.490	EPSD	TCGA;ICGC;COSMIC	4.810	Down-regulation
CAMK_CAMK2_CAMK2A_ST	Q9Y4D2	DAGLA	Q9UQM7	CAMK2A	S929	L933V	933	Missense	distal	4	no	6.348	6.450	EPSD	TCGA;ICGC;COSMIC	4.810	Up-regulation
CAMK_CAMK2_CAMK2A_ST	Q9Y4D2	DAGLA	Q9UQM7	CAMK2A	S954	R961C	961	Missense	distal	7	no	4.938	5.094	EPSD	TCGA;ICGC;COSMIC	4.810	Up-regulation
CAMK_CAMK2_CAMK2A_ST	Q9Y4D2	DAGLA	Q9UQM7	CAMK2A	S954	R961H	961	Missense	distal	7	no	4.938	4.890	EPSD	TCGA;ICGC;COSMIC	4.810	Down-regulation
CAMK_CAMK2_CAMK2A_ST	Q9Y4D2	DAGLA	Q9UQM7	CAMK2A	T1023	G1028E	1028	Missense	distal	5	no	4.713	4.834	EPSD	TCGA;ICGC;COSMIC;CCLE	4.810	Gain
CAMK_CAMK2_CAMK2A_ST	Q9BXL7	CARD11	Q9UQM7	CAMK2A	S116	E121Q	121	Missense	distal	5	no	7.539	7.459	PhosphoSitePlus	TCGA;ICGC;COSMIC	4.810	Down-regulation
CAMK_CAMK2_CAMK2A_ST	Q9BXL7	CARD11	Q9UQM7	CAMK2A	S116	P111H	111	Missense	distal	-5	no	7.539	7.412	PhosphoSitePlus	TCGA;ICGC;COSMIC	4.810	Down-regulation
CAMK_CAMK2_CAMK2A_ST	Q9BXL7	CARD11	Q9UQM7	CAMK2A	S116	R113W	113	Missense	distal	-3	no	7.539	-4.482	PhosphoSitePlus	TCGA;ICGC;COSMIC	4.810	Loss
CAMK_CAMK2_CAMK2A_ST	Q9BXL7	CARD11	Q9UQM7	CAMK2A	T117	E121Q	121	Missense	distal	4	no	6.080	5.948	EPSD	TCGA;ICGC;COSMIC	4.810	Down-regulation
CAMK_CAMK2_CAMK2A_ST	Q9BXL7	CARD11	Q9UQM7	CAMK2A	T117	P111H	111	Missense	distal	-6	no	6.080	5.939	EPSD	TCGA;ICGC;COSMIC	4.810	Down-regulation
CAMK_CAMK2_CAMK2A_ST	Q9BXL7	CARD11	Q9UQM7	CAMK2A	T117	H124R	124	Missense	distal	7	no	6.080	6.128	EPSD	TCGA;ICGC;COSMIC	4.810	Up-regulation
CAMK_CAMK2_CAMK2A_ST	Q9BXL7	CARD11	Q9UQM7	CAMK2A	T117	R113W	113	Missense	distal	-4	no	6.080	5.389	EPSD	TCGA;ICGC;COSMIC	4.810	Down-regulation
CAMK_CAMK2_CAMK2A_ST	Q9BXL7	CARD11	Q9UQM7	CAMK2A	S439	S433R	433	Missense	distal	-6	no	8.768	8.724	EPSD	TCGA;ICGC;COSMIC	4.810	Down-regulation
CAMK_CAMK2_CAMK2A_ST	Q9BXL7	CARD11	Q9UQM7	CAMK2A	S439	S433T	433	Missense	distal	-6	no	8.768	8.839	EPSD	TCGA;ICGC;COSMIC	4.810	Up-regulation
CAMK_CAMK2_CAMK2A_ST	Q9BXL7	CARD11	Q9UQM7	CAMK2A	S512	R518Q	518	Missense	distal	6	no	6.859	6.865	EPSD	TCGA;ICGC;COSMIC	4.810	Up-regulation
CAMK_CAMK2_CAMK2A_ST	Q9BXL7	CARD11	Q9UQM7	CAMK2A	S520	G526R	526	Missense	distal	6	no	5.861	5.922	EPSD	TCGA;ICGC;COSMIC;GDSC;CCLE	4.810	Up-regulation
CAMK_CAMK2_CAMK2A_ST	Q9BXL7	CARD11	Q9UQM7	CAMK2A	S520	F522V	522	Missense	proximal	2	no	5.861	7.136	EPSD	TCGA;ICGC;COSMIC	4.810	Up-regulation
CAMK_CAMK2_CAMK2A_ST	Q9BXL7	CARD11	Q9UQM7	CAMK2A	S520	R518Q	518	Missense	proximal	-2	no	5.861	6.078	EPSD	TCGA;ICGC;COSMIC	4.810	Up-regulation
CAMK_CAMK2_CAMK2A_ST	Q9BXL7	CARD11	Q9UQM7	CAMK2A	T586	H583R	583	Missense	distal	-3	no	2.461	7.959	EPSD	TCGA;ICGC;COSMIC	4.810	Gain
CAMK_CAMK2_CAMK2A_ST	Q9BXL7	CARD11	Q9UQM7	CAMK2A	S610	E607K	607	Missense	distal	-3	no	2.183	5.033	EPSD	TCGA;ICGC;COSMIC	4.810	Gain
CAMK_CAMK2_CAMK2A_ST	Q9BXL7	CARD11	Q9UQM7	CAMK2A	S618	S614T	614	Missense	distal	-4	no	5.235	4.954	EPSD	TCGA;ICGC;COSMIC	4.810	Down-regulation
CAMK_CAMK2_CAMK2A_ST	Q9BXL7	CARD11	Q9UQM7	CAMK2A	S618	S621F	621	Missense	distal	3	no	5.235	4.858	EPSD	TCGA;ICGC;COSMIC	4.810	Down-regulation
CAMK_CAMK2_CAMK2A_ST	Q9BXL7	CARD11	Q9UQM7	CAMK2A	S644	M639K	639	Missense	distal	-5	no	8.796	8.767	EPSD	TCGA	4.810	Down-regulation
CAMK_CAMK2_CAMK2A_ST	Q9BXL7	CARD11	Q9UQM7	CAMK2A	S644	F640L	640	Missense	distal	-4	no	8.796	9.016	EPSD	TCGA;ICGC;COSMIC	4.810	Up-regulation
CAMK_CAMK2_CAMK2A_ST	Q9BXL7	CARD11	Q9UQM7	CAMK2A	S644	S644Y	644	Missense	central	0	yes	8.796	0.000	EPSD	TCGA;ICGC	4.810	Loss
CAMK_CAMK2_CAMK2A_ST	Q9BXL7	CARD11	Q9UQM7	CAMK2A	S923	R918W	918	Missense	distal	-5	no	6.853	7.001	EPSD	TCGA;ICGC;COSMIC	4.810	Up-regulation
CAMK_CAMK2_CAMK2A_ST	Q9BXL7	CARD11	Q9UQM7	CAMK2A	S923	P926L	926	Missense	distal	3	no	6.853	6.813	EPSD	TCGA;ICGC;COSMIC	4.810	Down-regulation
CAMK_CAMK2_CAMK2A_ST	Q9BXL7	CARD11	Q9UQM7	CAMK2A	T1020	R1027Q	1027	Missense	distal	7	no	6.645	6.526	EPSD	TCGA;ICGC;COSMIC	4.810	Down-regulation
CAMK_CAMK2_CAMK2A_ST	Q9BXL7	CARD11	Q9UQM7	CAMK2A	T1020	Q1018R	1018	Missense	proximal	-2	no	6.645	6.428	EPSD	TCGA;ICGC;COSMIC	4.810	Down-regulation
CAMK_CAMK2_CAMK2A_ST	Q9BXL7	CARD11	Q9UQM7	CAMK2A	T1020	T1020M	1020	Missense	central	0	yes	6.645	0.000	EPSD	TCGA;ICGC;COSMIC	4.810	Loss
CAMK_CAMK2_CAMK2A_ST	Q01970	PLCB3	Q9UQM7	CAMK2A	S148	R149Q	149	Missense	proximal	1	no	5.158	5.130	EPSD	TCGA;ICGC;COSMIC;CCLE	4.810	Down-regulation
CAMK_CAMK2_CAMK2A_ST	Q01970	PLCB3	Q9UQM7	CAMK2A	S512	G518C	518	Missense	distal	6	no	5.940	5.836	EPSD	TCGA;ICGC	4.810	Down-regulation
CAMK_CAMK2_CAMK2A_ST	Q01970	PLCB3	Q9UQM7	CAMK2A	S512	G518V	518	Missense	distal	6	no	5.940	5.878	EPSD	TCGA;ICGC;COSMIC	4.810	Down-regulation
CAMK_CAMK2_CAMK2A_ST	Q01970	PLCB3	Q9UQM7	CAMK2A	S531	E528Q	528	Missense	distal	-3	no	4.112	5.659	EPSD	TCGA;ICGC;COSMIC	4.810	Gain
CAMK_CAMK2_CAMK2A_ST	Q01970	PLCB3	Q9UQM7	CAMK2A	S867	Q871H	871	Missense	distal	4	no	4.864	4.806	EPSD	TCGA;ICGC;COSMIC	4.810	Loss
CAMK_CAMK2_CAMK2A_ST	Q01970	PLCB3	Q9UQM7	CAMK2A	S1105	A1109S	1109	Missense	distal	4	no	9.060	9.114	EPSD	TCGA	4.810	Up-regulation
CAMK_CAMK2_CAMK2A_ST	P16070	CD44	Q9UQM7	CAMK2A	S182	S180R	180	Missense	proximal	-2	no	4.750	4.822	EPSD	TCGA;ICGC;COSMIC	4.810	Gain
CAMK_CAMK2_CAMK2A_ST	P16070	CD44	Q9UQM7	CAMK2A	S183	S180R	180	Missense	distal	-3	no	3.493	7.953	EPSD	TCGA;ICGC;COSMIC	4.810	Gain
CAMK_CAMK2_CAMK2A_ST	P16070	CD44	Q9UQM7	CAMK2A	S291	D287N	287	Missense	distal	-4	no	8.268	8.331	EPSD	TCGA;ICGC;COSMIC	4.810	Up-regulation
CAMK_CAMK2_CAMK2A_ST	P16070	CD44	Q9UQM7	CAMK2A	S291	G294E	294	Missense	distal	3	no	8.268	8.554	EPSD	TCGA;ICGC;COSMIC	4.810	Up-regulation
CAMK_CAMK2_CAMK2A_ST	P16070	CD44	Q9UQM7	CAMK2A	S291	S291R	291	Missense	central	0	yes	8.268	0.000	EPSD	TCGA;ICGC;COSMIC	4.810	Loss
CAMK_CAMK2_CAMK2A_ST	P16070	CD44	Q9UQM7	CAMK2A	S697	N700D	700	Missense	distal	3	no	5.717	5.844	EPSD	TCGA;COSMIC	4.810	Up-regulation
CAMK_CAMK2_CAMK2A_ST	P16070	CD44	Q9UQM7	CAMK2A	S697	G701R	701	Missense	distal	4	no	5.717	5.642	EPSD	TCGA;COSMIC	4.810	Down-regulation
CAMK_CAMK2_CAMK2A_ST	P16070	CD44	Q9UQM7	CAMK2A	S704	G701R	701	Missense	distal	-3	no	3.309	7.907	EPSD	TCGA;COSMIC	4.810	Gain
CAMK_CAMK2_CAMK2A_ST	P16070	CD44	Q9UQM7	CAMK2A	S706	E708D	708	Missense	proximal	2	no	5.701	6.617	PhosphoSitePlus	TCGA	4.810	Up-regulation
CAMK_CAMK2_CAMK2A_ST	P16070	CD44	Q9UQM7	CAMK2A	S706	N700D	700	Missense	distal	-6	no	5.701	5.679	PhosphoSitePlus	TCGA;COSMIC	4.810	Down-regulation
CAMK_CAMK2_CAMK2A_ST	P16070	CD44	Q9UQM7	CAMK2A	S706	G701R	701	Missense	distal	-5	no	5.701	5.594	PhosphoSitePlus	TCGA;COSMIC	4.810	Down-regulation
CAMK_CAMK2_CAMK2A_ST	Q14674	ESPL1	Q9UQM7	CAMK2A	S1641	R1647Q	1647	Missense	distal	6	no	8.168	8.174	EPSD	TCGA;ICGC;COSMIC	4.810	Up-regulation
CAMK_CAMK2_CAMK2A_ST	Q14674	ESPL1	Q9UQM7	CAMK2A	S1641	L1640F	1640	Missense	proximal	-1	no	8.168	8.037	EPSD	TCGA;ICGC;COSMIC	4.810	Down-regulation
CAMK_CAMK2_CAMK2A_ST	Q14674	ESPL1	Q9UQM7	CAMK2A	S1641	H1635Y	1635	Missense	distal	-6	no	8.168	8.290	EPSD	TCGA;ICGC;COSMIC	4.810	Up-regulation
CAMK_CAMK2_CAMK2A_ST	Q14674	ESPL1	Q9UQM7	CAMK2A	S1820	R1821C	1821	Missense	proximal	1	no	5.228	5.197	EPSD	TCGA;ICGC;COSMIC	4.810	Down-regulation
CAMK_CAMK2_CAMK2A_ST	O95180	CACNA1H	Q9UQM7	CAMK2A	S215	R208C	208	Missense	distal	-7	no	6.019	6.687	EPSD	TCGA;ICGC;COSMIC;GDSC;CCLE	4.810	Up-regulation
CAMK_CAMK2_CAMK2A_ST	O95180	CACNA1H	Q9UQM7	CAMK2A	S215	A209T	209	Missense	distal	-6	no	6.019	6.203	EPSD	TCGA;ICGC;COSMIC	4.810	Up-regulation
CAMK_CAMK2_CAMK2A_ST	O95180	CACNA1H	Q9UQM7	CAMK2A	S215	V213M	213	Missense	proximal	-2	no	6.019	6.512	EPSD	TCGA;ICGC;COSMIC;CCLE	4.810	Up-regulation
CAMK_CAMK2_CAMK2A_ST	O95180	CACNA1H	Q9UQM7	CAMK2A	S475	R474C	474	Missense	proximal	-1	no	5.128	4.800	EPSD	TCGA;ICGC;COSMIC	4.810	Loss
CAMK_CAMK2_CAMK2A_ST	O95180	CACNA1H	Q9UQM7	CAMK2A	S475	R469C	469	Missense	distal	-6	no	5.128	5.323	EPSD	TCGA;ICGC;COSMIC	4.810	Up-regulation
CAMK_CAMK2_CAMK2A_ST	O95180	CACNA1H	Q9UQM7	CAMK2A	S484	R487C	487	Missense	distal	3	no	5.694	5.431	EPSD	TCGA;ICGC;COSMIC	4.810	Down-regulation
CAMK_CAMK2_CAMK2A_ST	O95180	CACNA1H	Q9UQM7	CAMK2A	S1107	D1112Y	1112	Missense	distal	5	no	7.253	7.187	EPSD	TCGA;ICGC;COSMIC	4.810	Down-regulation
CAMK_CAMK2_CAMK2A_ST	O95180	CACNA1H	Q9UQM7	CAMK2A	S1107	R1105C	1105	Missense	proximal	-2	no	7.253	6.450	EPSD	TCGA;ICGC;COSMIC	4.810	Down-regulation
CAMK_CAMK2_CAMK2A_ST	O95180	CACNA1H	Q9UQM7	CAMK2A	S1108	D1112Y	1112	Missense	distal	4	no	7.388	7.412	EPSD	TCGA;ICGC;COSMIC	4.810	Up-regulation
CAMK_CAMK2_CAMK2A_ST	O95180	CACNA1H	Q9UQM7	CAMK2A	S1108	R1105C	1105	Missense	distal	-3	no	7.388	1.807	EPSD	TCGA;ICGC;COSMIC	4.810	Loss
CAMK_CAMK2_CAMK2A_ST	O95180	CACNA1H	Q9UQM7	CAMK2A	S1110	D1112Y	1112	Missense	proximal	2	no	5.115	1.539	EPSD	TCGA;ICGC;COSMIC	4.810	Loss
CAMK_CAMK2_CAMK2A_ST	O95180	CACNA1H	Q9UQM7	CAMK2A	S1110	R1105C	1105	Missense	distal	-5	no	5.115	5.114	EPSD	TCGA;ICGC;COSMIC	4.810	Down-regulation
CAMK_CAMK2_CAMK2A_ST	O95180	CACNA1H	Q9UQM7	CAMK2A	S1144	L1148P	1148	Missense	distal	4	no	8.371	8.408	EPSD	TCGA;ICGC;COSMIC	4.810	Up-regulation
CAMK_CAMK2_CAMK2A_ST	O95180	CACNA1H	Q9UQM7	CAMK2A	S1198	R1205L	1205	Missense	distal	7	no	9.663	9.723	PhosphoSitePlus	TCGA;ICGC;COSMIC	4.810	Up-regulation
CAMK_CAMK2_CAMK2A_ST	O95180	CACNA1H	Q9UQM7	CAMK2A	S1587	R1584M	1584	Missense	distal	-3	no	5.655	0.837	EPSD	TCGA;ICGC	4.810	Loss
CAMK_CAMK2_CAMK2A_ST	O95180	CACNA1H	Q9UQM7	CAMK2A	S1587	R1580C	1580	Missense	distal	-7	no	5.655	6.323	EPSD	TCGA;ICGC;COSMIC	4.810	Up-regulation
CAMK_CAMK2_CAMK2A_ST	O95180	CACNA1H	Q9UQM7	CAMK2A	S1587	R1585C	1585	Missense	proximal	-2	no	5.655	4.852	EPSD	TCGA;ICGC;CCLE	4.810	Down-regulation
CAMK_CAMK2_CAMK2A_ST	O95180	CACNA1H	Q9UQM7	CAMK2A	S1587	R1585H	1585	Missense	proximal	-2	no	5.655	5.534	EPSD	TCGA;ICGC;COSMIC	4.810	Down-regulation
CAMK_CAMK2_CAMK2A_ST	O95180	CACNA1H	Q9UQM7	CAMK2A	T1806	V1804M	1804	Missense	proximal	-2	no	5.373	5.866	EPSD	TCGA;ICGC;COSMIC;GDSC	4.810	Up-regulation
CAMK_CAMK2_CAMK2A_ST	O95180	CACNA1H	Q9UQM7	CAMK2A	T1806	R1803C	1803	Missense	distal	-3	no	5.373	-0.208	EPSD	TCGA;ICGC;COSMIC;GDSC;CCLE	4.810	Loss
CAMK_CAMK2_CAMK2A_ST	O95180	CACNA1H	Q9UQM7	CAMK2A	T2073	R2070H	2070	Missense	distal	-3	no	6.781	1.284	EPSD	TCGA;ICGC;COSMIC	4.810	Loss
CAMK_CAMK2_CAMK2A_ST	O95180	CACNA1H	Q9UQM7	CAMK2A	T2073	G2075R	2075	Missense	proximal	2	no	6.781	7.200	EPSD	TCGA;ICGC;COSMIC	4.810	Up-regulation
CAMK_CAMK2_CAMK2A_ST	O95180	CACNA1H	Q9UQM7	CAMK2A	T2073	V2079I	2079	Missense	distal	6	no	6.781	6.812	EPSD	TCGA;ICGC;COSMIC	4.810	Up-regulation
CAMK_CAMK2_CAMK2A_ST	O95180	CACNA1H	Q9UQM7	CAMK2A	T2073	R2070C	2070	Missense	distal	-3	no	6.781	1.200	EPSD	TCGA;ICGC;COSMIC	4.810	Loss
CAMK_CAMK2_CAMK2A_ST	O95180	CACNA1H	Q9UQM7	CAMK2A	S2137	L2132R	2132	Missense	distal	-5	no	8.990	9.011	EPSD	TCGA;ICGC;COSMIC	4.810	Up-regulation
CAMK_CAMK2_CAMK2A_ST	P78352	DLG4	Q9UQM7	CAMK2A	S478	D483Y	483	Missense	distal	5	no	7.225	7.159	EPSD	TCGA;ICGC;COSMIC	4.810	Down-regulation
CAMK_CAMK2_CAMK2A_ST	Q14457	BECN1	Q9UQM7	CAMK2A	S15	F16L	16	Missense	proximal	1	no	5.837	5.943	EPSD	TCGA;ICGC;COSMIC	4.810	Up-regulation
CAMK_CAMK2_CAMK2A_ST	Q14457	BECN1	Q9UQM7	CAMK2A	S90	P84L	84	Missense	distal	-6	no	9.575	9.580	PhosphoSitePlus	TCGA;ICGC;COSMIC	4.810	Up-regulation
CAMK_CAMK2_CAMK2A_ST	Q14457	BECN1	Q9UQM7	CAMK2A	S295	R292H	292	Missense	distal	-3	no	5.695	0.198	EPSD	TCGA;ICGC	4.810	Loss
CAMK_CAMK2_CAMK2A_ST	Q14457	BECN1	Q9UQM7	CAMK2A	S412	G411S	411	Missense	proximal	-1	no	5.732	5.878	EPSD	TCGA;ICGC;COSMIC	4.810	Up-regulation
CAMK_CAMK2_CAMK2A_ST	Q13224	GRIN2B	Q9UQM7	CAMK2A	S930	R926Q	926	Missense	distal	-4	no	6.367	6.261	EPSD	TCGA;ICGC;COSMIC	4.810	Down-regulation
CAMK_CAMK2_CAMK2A_ST	Q13224	GRIN2B	Q9UQM7	CAMK2A	S930	E928K	928	Missense	proximal	-2	no	6.367	6.590	EPSD	TCGA;ICGC;COSMIC	4.810	Up-regulation
CAMK_CAMK2_CAMK2A_ST	Q13224	GRIN2B	Q9UQM7	CAMK2A	S1043	K1045N	1045	Missense	proximal	2	no	2.932	4.880	EPSD	TCGA;ICGC;COSMIC	4.810	Gain
CAMK_CAMK2_CAMK2A_ST	Q13224	GRIN2B	Q9UQM7	CAMK2A	S1166	R1164C	1164	Missense	proximal	-2	no	5.799	4.996	EPSD	TCGA;ICGC;COSMIC	4.810	Down-regulation
CAMK_CAMK2_CAMK2A_ST	Q13224	GRIN2B	Q9UQM7	CAMK2A	S1166	G1170R	1170	Missense	distal	4	no	5.799	5.725	EPSD	TCGA;ICGC;COSMIC	4.810	Down-regulation
CAMK_CAMK2_CAMK2A_ST	Q13224	GRIN2B	Q9UQM7	CAMK2A	S1166	S1168R	1168	Missense	proximal	2	no	5.799	6.224	EPSD	TCGA;ICGC;COSMIC	4.810	Up-regulation
CAMK_CAMK2_CAMK2A_ST	Q13224	GRIN2B	Q9UQM7	CAMK2A	S1166	G1169R	1169	Missense	distal	3	no	5.799	5.855	EPSD	TCGA;ICGC;COSMIC;CCLE	4.810	Up-regulation
CAMK_CAMK2_CAMK2A_ST	Q13224	GRIN2B	Q9UQM7	CAMK2A	S1166	G1170E	1170	Missense	distal	4	no	5.799	6.026	EPSD	TCGA;ICGC;COSMIC	4.810	Up-regulation
CAMK_CAMK2_CAMK2A_ST	Q13224	GRIN2B	Q9UQM7	CAMK2A	S1166	D1161N	1161	Missense	distal	-5	no	5.799	5.811	EPSD	TCGA;ICGC;COSMIC	4.810	Up-regulation
CAMK_CAMK2_CAMK2A_ST	Q13224	GRIN2B	Q9UQM7	CAMK2A	S1303	R1299H	1299	Missense	distal	-4	no	11.156	11.033	PhosphoSitePlus	TCGA;ICGC;COSMIC;CCLE	4.810	Down-regulation
CAMK_CAMK2_CAMK2A_ST	Q13224	GRIN2B	Q9UQM7	CAMK2A	S1303	R1300Q	1300	Missense	distal	-3	no	11.156	7.585	PhosphoSitePlus	TCGA;ICGC;COSMIC	4.810	Down-regulation
CAMK_CAMK2_CAMK2A_ST	Q13224	GRIN2B	Q9UQM7	CAMK2A	S1303	R1299C	1299	Missense	distal	-4	no	11.156	10.522	PhosphoSitePlus	TCGA;ICGC;COSMIC;GDSC;CCLE	4.810	Down-regulation
CAMK_CAMK2_CAMK2A_ST	Q13224	GRIN2B	Q9UQM7	CAMK2A	S1303	N1296T	1296	Missense	distal	-7	no	11.156	11.162	PhosphoSitePlus	TCGA;ICGC	4.810	Up-regulation
CAMK_CAMK2_CAMK2A_ST	Q13224	GRIN2B	Q9UQM7	CAMK2A	S1323	A1318G	1318	Missense	distal	-5	no	7.497	7.526	EPSD	TCGA;ICGC;COSMIC	4.810	Up-regulation
CAMK_CAMK2_CAMK2A_ST	Q13224	GRIN2B	Q9UQM7	CAMK2A	S1323	R1320H	1320	Missense	distal	-3	no	7.497	2.000	EPSD	TCGA;ICGC;COSMIC	4.810	Loss
CAMK_CAMK2_CAMK2A_ST	Q13224	GRIN2B	Q9UQM7	CAMK2A	T1410	S1403F	1403	Missense	distal	-7	no	4.256	4.817	EPSD	TCGA;ICGC;COSMIC	4.810	Gain
CAMK_CAMK2_CAMK2A_ST	Q04760	GLO1	Q9UQM7	CAMK2A	S26	K28N	28	Missense	proximal	2	no	4.503	6.450	EPSD	TCGA;ICGC;COSMIC	4.810	Gain
CAMK_CAMK2_CAMK2A_ST	P37840	SNCA	Q9UQM7	CAMK2A	S9	G14E	14	Missense	distal	5	no	5.363	5.485	EPSD	TCGA;ICGC;COSMIC	4.810	Up-regulation
CAMK_CAMK2_CAMK2A_ST	P37840	SNCA	Q9UQM7	CAMK2A	S9	G14R	14	Missense	distal	5	no	5.363	5.405	EPSD	TCGA;ICGC;COSMIC	4.810	Up-regulation
CAMK_CAMK2_CAMK2A_ST	P37840	SNCA	Q9UQM7	CAMK2A	S9	D2Y	2	Missense	distal	-7	no	5.363	5.317	EPSD	TCGA;ICGC;COSMIC	4.810	Down-regulation
CAMK_CAMK2_CAMK2A_ST	P10636	MAPT	Q9UQM7	CAMK2A	S113	E117K	117	Missense	distal	4	no	4.846	4.670	EPSD	TCGA;ICGC;COSMIC	4.810	Loss
CAMK_CAMK2_CAMK2A_ST	P10636	MAPT	Q9UQM7	CAMK2A	S113	A118V	118	Missense	distal	5	no	4.846	4.628	EPSD	TCGA;ICGC;COSMIC	4.810	Loss
CAMK_CAMK2_CAMK2A_ST	P10636	MAPT	Q9UQM7	CAMK2A	T167	R168H	168	Missense	proximal	1	no	5.827	6.340	EPSD	TCGA;ICGC;COSMIC	4.810	Up-regulation
CAMK_CAMK2_CAMK2A_ST	P10636	MAPT	Q9UQM7	CAMK2A	T167	R168C	168	Missense	proximal	1	no	5.827	5.796	EPSD	TCGA;ICGC;COSMIC	4.810	Down-regulation
CAMK_CAMK2_CAMK2A_ST	P10636	MAPT	Q9UQM7	CAMK2A	S171	R168H	168	Missense	distal	-3	no	5.997	0.499	EPSD	TCGA;ICGC;COSMIC	4.810	Loss
CAMK_CAMK2_CAMK2A_ST	P10636	MAPT	Q9UQM7	CAMK2A	S171	R168C	168	Missense	distal	-3	no	5.997	0.416	EPSD	TCGA;ICGC;COSMIC	4.810	Loss
CAMK_CAMK2_CAMK2A_ST	P10636	MAPT	Q9UQM7	CAMK2A	S214	P212L	212	Missense	proximal	-2	no	8.732	8.622	EPSD	TCGA;ICGC;COSMIC	4.810	Down-regulation
CAMK_CAMK2_CAMK2A_ST	P10636	MAPT	Q9UQM7	CAMK2A	S214	E220K	220	Missense	distal	6	no	8.732	8.681	EPSD	TCGA;ICGC;COSMIC	4.810	Down-regulation
CAMK_CAMK2_CAMK2A_ST	P10636	MAPT	Q9UQM7	CAMK2A	S318	E314Q	314	Missense	distal	-4	no	6.384	6.222	EPSD	TCGA;ICGC;COSMIC	4.810	Down-regulation
CAMK_CAMK2_CAMK2A_ST	P10636	MAPT	Q9UQM7	CAMK2A	S318	H317P	317	Missense	proximal	-1	no	6.384	6.141	EPSD	TCGA;ICGC;COSMIC	4.810	Down-regulation
CAMK_CAMK2_CAMK2A_ST	P10636	MAPT	Q9UQM7	CAMK2A	S318	A316V	316	Missense	proximal	-2	no	6.384	5.966	EPSD	TCGA;ICGC;COSMIC	4.810	Down-regulation
CAMK_CAMK2_CAMK2A_ST	P10636	MAPT	Q9UQM7	CAMK2A	S318	E319D	319	Missense	proximal	1	no	6.384	5.870	EPSD	TCGA;ICGC;COSMIC	4.810	Down-regulation
CAMK_CAMK2_CAMK2A_ST	P10636	MAPT	Q9UQM7	CAMK2A	S341	E348V	348	Missense	distal	7	no	7.485	7.704	EPSD	TCGA;ICGC;COSMIC	4.810	Up-regulation
CAMK_CAMK2_CAMK2A_ST	P10636	MAPT	Q9UQM7	CAMK2A	S341	G339R	339	Missense	proximal	-2	no	7.485	7.714	EPSD	TCGA;ICGC;COSMIC	4.810	Up-regulation
CAMK_CAMK2_CAMK2A_ST	P10636	MAPT	Q9UQM7	CAMK2A	S341	S341F	341	Missense	central	0	yes	7.485	0.000	EPSD	TCGA;ICGC;COSMIC	4.810	Loss
CAMK_CAMK2_CAMK2A_ST	P10636	MAPT	Q9UQM7	CAMK2A	S369	Q373R	373	Missense	distal	4	no	5.352	5.183	EPSD	TCGA;ICGC;COSMIC	4.810	Down-regulation
CAMK_CAMK2_CAMK2A_ST	P10636	MAPT	Q9UQM7	CAMK2A	S369	K366E	366	Missense	distal	-3	no	5.352	2.502	EPSD	TCGA;ICGC;COSMIC	4.810	Loss
CAMK_CAMK2_CAMK2A_ST	P10636	MAPT	Q9UQM7	CAMK2A	S382	G387R	387	Missense	distal	5	no	4.976	5.019	EPSD	TCGA;COSMIC	4.810	Up-regulation
CAMK_CAMK2_CAMK2A_ST	P10636	MAPT	Q9UQM7	CAMK2A	S382	R377C	377	Missense	distal	-5	no	4.976	4.975	EPSD	TCGA;COSMIC	4.810	Down-regulation
CAMK_CAMK2_CAMK2A_ST	P10636	MAPT	Q9UQM7	CAMK2A	S388	G387R	387	Missense	proximal	-1	no	5.329	5.387	EPSD	TCGA;COSMIC	4.810	Up-regulation
CAMK_CAMK2_CAMK2A_ST	P10636	MAPT	Q9UQM7	CAMK2A	S451	E456K	456	Missense	distal	5	no	8.319	8.349	EPSD	TCGA;ICGC;COSMIC	4.810	Up-regulation
CAMK_CAMK2_CAMK2A_ST	P10636	MAPT	Q9UQM7	CAMK2A	S451	S452C	452	Missense	proximal	1	no	8.319	8.101	EPSD	TCGA;ICGC;COSMIC	4.810	Down-regulation
CAMK_CAMK2_CAMK2A_ST	P10636	MAPT	Q9UQM7	CAMK2A	S451	S444F	444	Missense	distal	-7	no	8.319	8.880	EPSD	TCGA;ICGC	4.810	Up-regulation
CAMK_CAMK2_CAMK2A_ST	P10636	MAPT	Q9UQM7	CAMK2A	S451	S452Y	452	Missense	proximal	1	no	8.319	8.216	EPSD	TCGA;ICGC;COSMIC	4.810	Down-regulation
CAMK_CAMK2_CAMK2A_ST	P10636	MAPT	Q9UQM7	CAMK2A	T470	R472Q	472	Missense	proximal	2	no	5.245	4.614	EPSD	TCGA	4.810	Loss
CAMK_CAMK2_CAMK2A_ST	P10636	MAPT	Q9UQM7	CAMK2A	T470	R472W	472	Missense	proximal	2	no	5.245	3.649	EPSD	TCGA;COSMIC	4.810	Loss
Other_Aur_AURKA_ST	O43379	WDR62	O14965	AURKA	S33	P36S	36	Missense	distal	3	no	40.800	41.452	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	39.062	Up-regulation
Other_Aur_AURKA_ST	O43379	WDR62	O14965	AURKA	S33	R28L	28	Missense	distal	-5	no	40.800	40.787	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	39.062	Down-regulation
Other_Aur_AURKA_ST	O43379	WDR62	O14965	AURKA	S49	E54K	54	Missense	distal	5	no	46.700	47.227	PhosphoSitePlus;EPSD	TCGA;ICGC;COSMIC	39.062	Up-regulation
Other_Aur_AURKA_ST	O43379	WDR62	O14965	AURKA	T50	E54K	54	Missense	distal	4	no	45.222	45.207	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	39.062	Down-regulation
Other_Aur_AURKA_ST	O43379	WDR62	O14965	AURKA	S211	S207L	207	Missense	distal	-4	no	41.116	40.350	EPSD	TCGA;ICGC;COSMIC	39.062	Down-regulation
Other_Aur_AURKA_ST	O43379	WDR62	O14965	AURKA	S926	G923R	923	Missense	distal	-3	no	37.231	42.424	EPSD	TCGA	39.062	Gain
Other_Aur_AURKA_ST	O43379	WDR62	O14965	AURKA	S979	K984M	984	Missense	distal	5	no	39.825	37.463	EPSD	TCGA;ICGC;COSMIC	39.062	Loss
Other_Aur_AURKA_ST	O43379	WDR62	O14965	AURKA	S980	K984M	984	Missense	distal	4	no	42.627	43.062	EPSD	TCGA;ICGC;COSMIC	39.062	Up-regulation
Other_Aur_AURKA_ST	O43379	WDR62	O14965	AURKA	S980	S987N	987	Missense	distal	7	no	42.627	42.548	EPSD	TCGA;ICGC;COSMIC	39.062	Down-regulation
Other_Aur_AURKA_ST	Q9UNN5	FAF1	O14965	AURKA	S212	G213V	213	Missense	proximal	1	no	43.863	46.203	EPSD	TCGA;ICGC;COSMIC	39.062	Up-regulation
Other_Aur_AURKA_ST	Q9UNN5	FAF1	O14965	AURKA	S269	R275Q	275	Missense	distal	6	no	39.220	39.176	EPSD	TCGA;ICGC;COSMIC	39.062	Down-regulation
Other_Aur_AURKA_ST	Q9UNN5	FAF1	O14965	AURKA	S270	R275Q	275	Missense	distal	5	no	41.982	44.363	EPSD	TCGA;ICGC;COSMIC	39.062	Up-regulation
Other_Aur_AURKA_ST	Q9UNN5	FAF1	O14965	AURKA	S289	D290N	290	Missense	proximal	1	no	44.167	38.592	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	39.062	Loss
Other_Aur_AURKA_ST	Q9UNN5	FAF1	O14965	AURKA	S289	V285A	285	Missense	distal	-4	no	44.167	40.492	EPSD;PhosphoSitePlus	TCGA;ICGC	39.062	Down-regulation
Other_Aur_AURKA_ST	Q9UNN5	FAF1	O14965	AURKA	S291	D290N	290	Missense	proximal	-1	no	43.031	39.870	PhosphoSitePlus;EPSD	TCGA;ICGC;COSMIC	39.062	Down-regulation
Other_Aur_AURKA_ST	Q9UNN5	FAF1	O14965	AURKA	S291	V285A	285	Missense	distal	-6	no	43.031	43.867	PhosphoSitePlus;EPSD	TCGA;ICGC	39.062	Up-regulation
Other_Aur_AURKA_ST	Q9UNN5	FAF1	O14965	AURKA	S320	A316V	316	Missense	distal	-4	no	36.193	39.868	EPSD	TCGA;ICGC;COSMIC	39.062	Gain
Other_Aur_AURKA_ST	Q9UNN5	FAF1	O14965	AURKA	S556	E549D	549	Missense	distal	-7	no	42.981	43.718	EPSD	TCGA;ICGC;COSMIC	39.062	Up-regulation
Other_Aur_AURKA_ST	Q9UNN5	FAF1	O14965	AURKA	S556	R554W	554	Missense	proximal	-2	no	42.981	-143.726	EPSD	TCGA;ICGC;COSMIC;CCLE	39.062	Loss
Other_Aur_AURKA_ST	O14965	AURKA	O14965	AURKA	S41	A44T	44	Missense	distal	3	no	45.936	44.805	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	39.062	Down-regulation
Other_Aur_AURKA_ST	O14965	AURKA	O14965	AURKA	S41	S41N	41	Missense	central	0	yes	45.936	0.000	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	39.062	Loss
Other_Aur_AURKA_ST	O14965	AURKA	O14965	AURKA	S51	R56H	56	Missense	distal	5	no	40.549	41.057	EPSD	TCGA;ICGC;COSMIC	39.062	Up-regulation
Other_Aur_AURKA_ST	O14965	AURKA	O14965	AURKA	S51	R56C	56	Missense	distal	5	no	40.549	42.698	EPSD	TCGA;ICGC;COSMIC	39.062	Up-regulation
Other_Aur_AURKA_ST	O14965	AURKA	O14965	AURKA	S51	A44T	44	Missense	distal	-7	no	40.549	40.090	EPSD	TCGA;ICGC;COSMIC	39.062	Down-regulation
Other_Aur_AURKA_ST	O14965	AURKA	O14965	AURKA	S51	S53Y	53	Missense	proximal	2	no	40.549	41.790	EPSD	TCGA;ICGC;COSMIC	39.062	Up-regulation
Other_Aur_AURKA_ST	O14965	AURKA	O14965	AURKA	S51	N52H	52	Missense	proximal	1	no	40.549	43.277	EPSD	TCGA;ICGC;COSMIC	39.062	Up-regulation
Other_Aur_AURKA_ST	O14965	AURKA	O14965	AURKA	S67	H68Q	68	Missense	proximal	1	no	44.094	46.974	PhosphoSitePlus;EPSD	TCGA	39.062	Up-regulation
Other_Aur_AURKA_ST	O14965	AURKA	O14965	AURKA	S83	S89C	89	Missense	distal	6	no	43.988	43.799	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	39.062	Down-regulation
Other_Aur_AURKA_ST	O14965	AURKA	O14965	AURKA	S83	A81V	81	Missense	proximal	-2	no	43.988	44.586	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	39.062	Up-regulation
Other_Aur_AURKA_ST	O14965	AURKA	O14965	AURKA	S83	S83N	83	Missense	central	0	yes	43.988	0.000	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	39.062	Loss
Other_Aur_AURKA_ST	O14965	AURKA	O14965	AURKA	S83	V84E	84	Missense	proximal	1	no	43.988	41.108	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	39.062	Down-regulation
Other_Aur_AURKA_ST	O14965	AURKA	O14965	AURKA	S98	P103S	103	Missense	distal	5	no	45.902	46.564	EPSD;PhosphoSitePlus	TCGA;ICGC	39.062	Up-regulation
Other_Aur_AURKA_ST	O14965	AURKA	O14965	AURKA	S98	P101S	101	Missense	distal	3	no	45.902	46.554	EPSD;PhosphoSitePlus	TCGA;ICGC	39.062	Up-regulation
Other_Aur_AURKA_ST	O14965	AURKA	O14965	AURKA	S98	K97N	97	Missense	proximal	-1	no	45.902	44.422	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	39.062	Down-regulation
Other_Aur_AURKA_ST	O14965	AURKA	O14965	AURKA	S104	P103S	103	Missense	proximal	-1	no	48.023	48.237	EPSD;PhosphoSitePlus	TCGA;ICGC	39.062	Up-regulation
Other_Aur_AURKA_ST	O14965	AURKA	O14965	AURKA	S104	P101S	101	Missense	distal	-3	no	48.023	50.202	EPSD;PhosphoSitePlus	TCGA;ICGC	39.062	Up-regulation
Other_Aur_AURKA_ST	O14965	AURKA	O14965	AURKA	S104	K97N	97	Missense	distal	-7	no	48.023	47.725	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	39.062	Down-regulation
Other_Aur_AURKA_ST	O14965	AURKA	O14965	AURKA	S226	K227N	227	Missense	proximal	1	no	43.359	37.977	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	39.062	Loss
Other_Aur_AURKA_ST	O14965	AURKA	O14965	AURKA	S226	D229E	229	Missense	distal	3	no	43.359	42.315	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	39.062	Down-regulation
Other_Aur_AURKA_ST	O14965	AURKA	O14965	AURKA	S266	E260D	260	Missense	distal	-6	no	46.555	46.878	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	39.062	Up-regulation
Other_Aur_AURKA_ST	O14965	AURKA	O14965	AURKA	S278	A281T	281	Missense	distal	3	no	45.129	43.997	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	39.062	Down-regulation
Other_Aur_AURKA_ST	O14965	AURKA	O14965	AURKA	T287	A281T	281	Missense	distal	-6	no	51.557	51.336	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	39.062	Down-regulation
Other_Aur_AURKA_ST	O14965	AURKA	O14965	AURKA	T288	A281T	281	Missense	distal	-7	no	63.877	63.419	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	39.062	Down-regulation
Other_Aur_AURKA_ST	O14965	AURKA	O14965	AURKA	S342	E336D	336	Missense	distal	-6	no	47.892	48.215	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	39.062	Up-regulation
Other_Aur_AURKA_ST	O14965	AURKA	O14965	AURKA	S342	R343Q	343	Missense	proximal	1	no	47.892	48.783	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC;GDSC	39.062	Up-regulation
Other_Aur_AURKA_ST	O15143	ARPC1B	O14965	AURKA	T89	W86C	86	Missense	distal	-3	no	-31.493	43.142	EPSD	TCGA;ICGC;COSMIC	39.062	Gain
Other_Aur_AURKA_ST	O15143	ARPC1B	O14965	AURKA	S310	S311F	311	Missense	proximal	1	no	32.824	39.304	EPSD	TCGA;ICGC;COSMIC	39.062	Gain
Other_Aur_AURKA_ST	Q14980	NUMA1	O14965	AURKA	S83	E79Q	79	Missense	distal	-4	no	44.362	42.998	EPSD	TCGA;ICGC;COSMIC	39.062	Down-regulation
Other_Aur_AURKA_ST	Q14980	NUMA1	O14965	AURKA	T163	E167G	167	Missense	distal	4	no	44.303	44.122	EPSD	TCGA;ICGC;COSMIC	39.062	Down-regulation
Other_Aur_AURKA_ST	Q14980	NUMA1	O14965	AURKA	S271	A269T	269	Missense	proximal	-2	no	41.767	34.192	EPSD	TCGA;ICGC;COSMIC	39.062	Loss
Other_Aur_AURKA_ST	Q14980	NUMA1	O14965	AURKA	S271	K276N	276	Missense	distal	5	no	41.767	40.844	EPSD	TCGA;ICGC;COSMIC	39.062	Down-regulation
Other_Aur_AURKA_ST	Q14980	NUMA1	O14965	AURKA	S324	G321R	321	Missense	distal	-3	no	35.553	40.746	EPSD	TCGA;ICGC	39.062	Gain
Other_Aur_AURKA_ST	Q14980	NUMA1	O14965	AURKA	S395	S395P	395	Missense	central	0	yes	47.790	0.000	EPSD	TCGA;ICGC;COSMIC	39.062	Loss
Other_Aur_AURKA_ST	Q14980	NUMA1	O14965	AURKA	S633	R631W	631	Missense	proximal	-2	no	48.213	-138.495	EPSD	TCGA;ICGC;COSMIC	39.062	Loss
Other_Aur_AURKA_ST	Q14980	NUMA1	O14965	AURKA	S717	S710P	710	Missense	distal	-7	no	39.501	41.361	EPSD	TCGA;ICGC	39.062	Up-regulation
Other_Aur_AURKA_ST	Q14980	NUMA1	O14965	AURKA	S1145	Q1142R	1142	Missense	distal	-3	no	38.509	48.172	EPSD	TCGA;ICGC;COSMIC	39.062	Gain
Other_Aur_AURKA_ST	Q14980	NUMA1	O14965	AURKA	S1162	A1158T	1158	Missense	distal	-4	no	36.980	41.938	EPSD	TCGA;ICGC;COSMIC	39.062	Gain
Other_Aur_AURKA_ST	Q14980	NUMA1	O14965	AURKA	S1203	E1206Q	1206	Missense	distal	3	no	44.554	44.167	EPSD	TCGA;ICGC;COSMIC	39.062	Down-regulation
Other_Aur_AURKA_ST	Q14980	NUMA1	O14965	AURKA	S1203	R1196H	1196	Missense	distal	-7	no	44.554	43.079	EPSD	TCGA;ICGC	39.062	Down-regulation
Other_Aur_AURKA_ST	Q14980	NUMA1	O14965	AURKA	S1772	E1771G	1771	Missense	proximal	-1	no	49.153	49.991	EPSD	TCGA	39.062	Up-regulation
Other_Aur_AURKA_ST	Q14980	NUMA1	O14965	AURKA	T1804	R1810H	1810	Missense	distal	6	no	44.896	44.900	EPSD;PhosphoSitePlus	TCGA;COSMIC;GDSC;CCLE	39.062	Up-regulation
Other_Aur_AURKA_ST	Q14980	NUMA1	O14965	AURKA	T1804	R1810C	1810	Missense	distal	6	no	44.896	44.726	EPSD;PhosphoSitePlus	TCGA;COSMIC;CCLE	39.062	Down-regulation
Other_Aur_AURKA_ST	Q14980	NUMA1	O14965	AURKA	T1811	R1810H	1810	Missense	proximal	-1	no	53.552	53.143	EPSD;PhosphoSitePlus	TCGA;COSMIC;GDSC;CCLE	39.062	Down-regulation
Other_Aur_AURKA_ST	Q14980	NUMA1	O14965	AURKA	T1811	R1810C	1810	Missense	proximal	-1	no	53.552	53.336	EPSD;PhosphoSitePlus	TCGA;COSMIC;CCLE	39.062	Down-regulation
Other_Aur_AURKA_ST	Q14980	NUMA1	O14965	AURKA	T1812	R1810H	1810	Missense	proximal	-2	no	57.388	50.149	EPSD;PhosphoSitePlus	TCGA;COSMIC;GDSC;CCLE	39.062	Down-regulation
Other_Aur_AURKA_ST	Q14980	NUMA1	O14965	AURKA	T1812	R1810C	1810	Missense	proximal	-2	no	57.388	42.091	EPSD;PhosphoSitePlus	TCGA;COSMIC;CCLE	39.062	Down-regulation
Other_Aur_AURKA_ST	Q14980	NUMA1	O14965	AURKA	S1830	E1827Q	1827	Missense	distal	-3	no	41.852	41.553	EPSD	TCGA;COSMIC	39.062	Down-regulation
Other_Aur_AURKA_ST	Q14980	NUMA1	O14965	AURKA	T1851	S1852Y	1852	Missense	proximal	1	no	41.206	45.283	EPSD	TCGA;COSMIC	39.062	Up-regulation
Other_Aur_AURKA_ST	Q14980	NUMA1	O14965	AURKA	T1879	L1873V	1873	Missense	distal	-6	no	45.315	46.226	EPSD	TCGA;COSMIC	39.062	Up-regulation
Other_Aur_AURKA_ST	Q14980	NUMA1	O14965	AURKA	T1879	R1885C	1885	Missense	distal	6	no	45.315	45.144	EPSD	TCGA;COSMIC	39.062	Down-regulation
Other_Aur_AURKA_ST	Q14980	NUMA1	O14965	AURKA	T1879	R1881H	1881	Missense	proximal	2	no	45.315	44.211	EPSD	TCGA;COSMIC	39.062	Down-regulation
Other_Aur_AURKA_ST	Q14980	NUMA1	O14965	AURKA	T1879	S1882N	1882	Missense	distal	3	no	45.315	41.585	EPSD	TCGA	39.062	Down-regulation
Other_Aur_AURKA_ST	Q14980	NUMA1	O14965	AURKA	S1883	S1887F	1887	Missense	distal	4	no	42.852	43.334	EPSD	TCGA	39.062	Up-regulation
Other_Aur_AURKA_ST	Q14980	NUMA1	O14965	AURKA	S1883	G1890R	1890	Missense	distal	7	no	42.852	42.714	EPSD	TCGA;COSMIC	39.062	Down-regulation
Other_Aur_AURKA_ST	Q14980	NUMA1	O14965	AURKA	S1883	R1885C	1885	Missense	proximal	2	no	42.852	46.005	EPSD	TCGA;COSMIC	39.062	Up-regulation
Other_Aur_AURKA_ST	Q14980	NUMA1	O14965	AURKA	S1883	R1881H	1881	Missense	proximal	-2	no	42.852	35.613	EPSD	TCGA;COSMIC	39.062	Loss
Other_Aur_AURKA_ST	Q14980	NUMA1	O14965	AURKA	S1883	S1882N	1882	Missense	proximal	-1	no	42.852	41.012	EPSD	TCGA	39.062	Down-regulation
Other_Aur_AURKA_ST	Q14980	NUMA1	O14965	AURKA	S1887	G1894R	1894	Missense	distal	7	no	54.760	54.622	PhosphoSitePlus;EPSD	TCGA;COSMIC	39.062	Down-regulation
Other_Aur_AURKA_ST	Q14980	NUMA1	O14965	AURKA	S1887	S1887F	1887	Missense	central	0	yes	54.760	0.000	PhosphoSitePlus;EPSD	TCGA	39.062	Loss
Other_Aur_AURKA_ST	Q14980	NUMA1	O14965	AURKA	S1887	G1890R	1890	Missense	distal	3	no	54.760	54.101	PhosphoSitePlus;EPSD	TCGA;COSMIC	39.062	Down-regulation
Other_Aur_AURKA_ST	Q14980	NUMA1	O14965	AURKA	S1887	R1885C	1885	Missense	proximal	-2	no	54.760	39.463	PhosphoSitePlus;EPSD	TCGA;COSMIC	39.062	Down-regulation
Other_Aur_AURKA_ST	Q14980	NUMA1	O14965	AURKA	S1887	R1881H	1881	Missense	distal	-6	no	54.760	52.591	PhosphoSitePlus;EPSD	TCGA;COSMIC	39.062	Down-regulation
Other_Aur_AURKA_ST	Q14980	NUMA1	O14965	AURKA	S1887	S1882N	1882	Missense	distal	-5	no	54.760	54.808	PhosphoSitePlus;EPSD	TCGA	39.062	Up-regulation
Other_Aur_AURKA_ST	Q14980	NUMA1	O14965	AURKA	S1892	G1890R	1890	Missense	proximal	-2	no	29.966	40.110	EPSD	TCGA;COSMIC	39.062	Gain
Other_Aur_AURKA_ST	Q14980	NUMA1	O14965	AURKA	S1893	G1890R	1890	Missense	distal	-3	no	35.626	40.820	EPSD	TCGA;COSMIC	39.062	Gain
Other_Aur_AURKA_ST	Q14980	NUMA1	O14965	AURKA	S1901	G1894R	1894	Missense	distal	-7	no	48.810	50.697	EPSD	TCGA;COSMIC	39.062	Up-regulation
Other_Aur_AURKA_ST	Q14980	NUMA1	O14965	AURKA	S1901	G1905S	1905	Missense	distal	4	no	48.810	48.532	EPSD	TCGA;COSMIC	39.062	Down-regulation
Other_Aur_AURKA_ST	Q14980	NUMA1	O14965	AURKA	S1901	G1905D	1905	Missense	distal	4	no	48.810	48.739	EPSD	TCGA	39.062	Down-regulation
Other_Aur_AURKA_ST	Q14980	NUMA1	O14965	AURKA	S1969	R1967Q	1967	Missense	proximal	-2	no	47.323	36.684	EPSD;PhosphoSitePlus	TCGA;COSMIC	39.062	Loss
Other_Aur_AURKA_ST	Q14980	NUMA1	O14965	AURKA	S1969	R1966H	1966	Missense	distal	-3	no	47.323	41.550	EPSD;PhosphoSitePlus	TCGA;COSMIC	39.062	Down-regulation
Other_Aur_AURKA_ST	Q14980	NUMA1	O14965	AURKA	S1991	R1987H	1987	Missense	distal	-4	no	67.005	62.570	EPSD;PhosphoSitePlus	TCGA;COSMIC;GDSC;CCLE	39.062	Down-regulation
Other_Aur_AURKA_ST	Q14980	NUMA1	O14965	AURKA	S2026	R2019Q	2019	Missense	distal	-7	no	40.380	39.857	EPSD	TCGA	39.062	Down-regulation
Other_Aur_AURKA_ST	Q14980	NUMA1	O14965	AURKA	S2026	R2023H	2023	Missense	distal	-3	no	40.380	34.607	EPSD	TCGA	39.062	Loss
Other_Aur_AURKA_ST	Q14980	NUMA1	O14965	AURKA	S2047	S2051N	2051	Missense	distal	4	no	49.503	48.628	EPSD;PhosphoSitePlus	TCGA;COSMIC	39.062	Down-regulation
Other_Aur_AURKA_ST	Q14980	NUMA1	O14965	AURKA	S2047	R2045C	2045	Missense	proximal	-2	no	49.503	34.205	EPSD;PhosphoSitePlus	TCGA;COSMIC	39.062	Loss
Other_Aur_AURKA_ST	Q14980	NUMA1	O14965	AURKA	S2047	R2045H	2045	Missense	proximal	-2	no	49.503	42.264	EPSD;PhosphoSitePlus	TCGA;COSMIC	39.062	Down-regulation
Other_Aur_AURKA_ST	Q14980	NUMA1	O14965	AURKA	S2062	R2066W	2066	Missense	distal	4	no	39.183	40.136	EPSD	TCGA;COSMIC	39.062	Up-regulation
Other_Aur_AURKA_ST	Q14980	NUMA1	O14965	AURKA	S2062	L2064V	2064	Missense	proximal	2	no	39.183	39.710	EPSD	TCGA;COSMIC	39.062	Up-regulation
Other_Aur_AURKA_ST	Q14980	NUMA1	O14965	AURKA	S2062	P2056S	2056	Missense	distal	-6	no	39.183	39.733	EPSD	TCGA	39.062	Up-regulation
Other_Aur_AURKA_ST	Q14980	NUMA1	O14965	AURKA	S2062	A2068S	2068	Missense	distal	6	no	39.183	39.175	EPSD	TCGA;COSMIC	39.062	Down-regulation
Other_Aur_AURKA_ST	Q14980	NUMA1	O14965	AURKA	S2069	R2066W	2066	Missense	distal	-3	no	40.768	-38.404	EPSD	TCGA;COSMIC	39.062	Loss
Other_Aur_AURKA_ST	Q14980	NUMA1	O14965	AURKA	S2069	L2064V	2064	Missense	distal	-5	no	40.768	40.772	EPSD	TCGA;COSMIC	39.062	Up-regulation
Other_Aur_AURKA_ST	Q14980	NUMA1	O14965	AURKA	S2069	K2075Q	2075	Missense	distal	6	no	40.768	40.933	EPSD	TCGA;COSMIC	39.062	Up-regulation
Other_Aur_AURKA_ST	Q14980	NUMA1	O14965	AURKA	S2069	A2068S	2068	Missense	proximal	-1	no	40.768	40.655	EPSD	TCGA;COSMIC	39.062	Down-regulation
Other_Aur_AURKA_ST	Q14980	NUMA1	O14965	AURKA	T2080	K2075Q	2075	Missense	distal	-5	no	40.306	40.321	EPSD	TCGA;COSMIC	39.062	Up-regulation
Other_Aur_AURKA_ST	Q14980	NUMA1	O14965	AURKA	T2080	R2081C	2081	Missense	proximal	1	no	40.306	35.173	EPSD	TCGA;COSMIC	39.062	Loss
Other_Aur_AURKA_ST	Q14980	NUMA1	O14965	AURKA	T2084	R2081C	2081	Missense	distal	-3	no	43.308	38.771	EPSD;PhosphoSitePlus	TCGA;COSMIC	39.062	Loss
Other_Aur_AURKA_ST	Q96EZ8	MCRS1	O14965	AURKA	S48	R46Q	46	Missense	proximal	-2	no	39.106	28.467	EPSD	TCGA;COSMIC	39.062	Loss
Other_Aur_AURKA_ST	Q96R06	SPAG5	O14965	AURKA	S21	G18R	18	Missense	distal	-3	no	35.936	41.129	EPSD	TCGA;ICGC;COSMIC	39.062	Gain
Other_Aur_AURKA_ST	Q96R06	SPAG5	O14965	AURKA	S362	S367L	367	Missense	distal	5	no	40.293	39.048	EPSD	TCGA;ICGC;COSMIC	39.062	Loss
Other_Aur_AURKA_ST	Q96R06	SPAG5	O14965	AURKA	S362	R360L	360	Missense	proximal	-2	no	40.293	30.572	EPSD	TCGA;ICGC;COSMIC	39.062	Loss
Other_Aur_AURKA_ST	Q96R06	SPAG5	O14965	AURKA	S362	S364F	364	Missense	proximal	2	no	40.293	39.598	EPSD	TCGA;ICGC;COSMIC	39.062	Down-regulation
Other_Aur_AURKA_ST	Q96R06	SPAG5	O14965	AURKA	S367	S367L	367	Missense	central	0	yes	44.908	0.000	EPSD	TCGA;ICGC;COSMIC	39.062	Loss
Other_Aur_AURKA_ST	Q96R06	SPAG5	O14965	AURKA	S367	D371Y	371	Missense	distal	4	no	44.908	44.452	EPSD	TCGA;ICGC;COSMIC	39.062	Down-regulation
Other_Aur_AURKA_ST	Q96R06	SPAG5	O14965	AURKA	S367	R360L	360	Missense	distal	-7	no	44.908	44.522	EPSD	TCGA;ICGC;COSMIC	39.062	Down-regulation
Other_Aur_AURKA_ST	Q96R06	SPAG5	O14965	AURKA	S367	S364F	364	Missense	distal	-3	no	44.908	39.292	EPSD	TCGA;ICGC;COSMIC	39.062	Down-regulation
Other_Aur_AURKA_ST	Q96R06	SPAG5	O14965	AURKA	T466	P464S	464	Missense	proximal	-2	no	37.578	39.479	EPSD	TCGA;ICGC	39.062	Gain
Other_Aur_AURKA_ST	Q96R06	SPAG5	O14965	AURKA	T466	P462S	462	Missense	distal	-4	no	37.578	39.496	EPSD	TCGA;ICGC;COSMIC	39.062	Gain
Other_Aur_AURKA_ST	Q14203	DCTN1	O14965	AURKA	S92	R90C	90	Missense	proximal	-2	no	43.751	28.454	EPSD	TCGA;ICGC;COSMIC	39.062	Loss
Other_Aur_AURKA_ST	Q14203	DCTN1	O14965	AURKA	S112	D110Y	110	Missense	proximal	-2	no	40.931	35.718	EPSD	TCGA;ICGC;COSMIC	39.062	Loss
Other_Aur_AURKA_ST	Q14203	DCTN1	O14965	AURKA	S112	P106L	106	Missense	distal	-6	no	40.931	39.951	EPSD	TCGA;COSMIC	39.062	Down-regulation
Other_Aur_AURKA_ST	Q14203	DCTN1	O14965	AURKA	T145	R149G	149	Missense	distal	4	no	39.286	40.096	EPSD	TCGA;ICGC;COSMIC	39.062	Up-regulation
Other_Aur_AURKA_ST	Q14203	DCTN1	O14965	AURKA	T145	R148W	148	Missense	distal	3	no	39.286	37.560	EPSD	TCGA;COSMIC	39.062	Loss
Other_Aur_AURKA_ST	Q14203	DCTN1	O14965	AURKA	T145	R143Q	143	Missense	proximal	-2	no	39.286	28.647	EPSD	TCGA;COSMIC	39.062	Loss
Other_Aur_AURKA_ST	Q14203	DCTN1	O14965	AURKA	T146	R149G	149	Missense	distal	3	no	57.314	57.973	EPSD	TCGA;ICGC;COSMIC	39.062	Up-regulation
Other_Aur_AURKA_ST	Q14203	DCTN1	O14965	AURKA	T146	R148W	148	Missense	proximal	2	no	57.314	57.104	EPSD	TCGA;COSMIC	39.062	Down-regulation
Other_Aur_AURKA_ST	Q14203	DCTN1	O14965	AURKA	T146	R143Q	143	Missense	distal	-3	no	57.314	47.651	EPSD	TCGA;COSMIC	39.062	Down-regulation
Other_Aur_AURKA_ST	Q14203	DCTN1	O14965	AURKA	S172	P169L	169	Missense	distal	-3	no	39.383	40.526	EPSD	TCGA;COSMIC	39.062	Up-regulation
Other_Aur_AURKA_ST	Q14203	DCTN1	O14965	AURKA	S203	P209R	209	Missense	distal	6	no	44.393	44.431	EPSD	TCGA;COSMIC	39.062	Up-regulation
Other_Aur_AURKA_ST	Q14203	DCTN1	O14965	AURKA	S212	P209R	209	Missense	distal	-3	no	31.573	40.232	EPSD	TCGA;COSMIC	39.062	Gain
Other_Aur_AURKA_ST	Q14203	DCTN1	O14965	AURKA	S351	E348K	348	Missense	distal	-3	no	40.649	42.188	EPSD	TCGA;COSMIC	39.062	Up-regulation
Other_Aur_AURKA_ST	Q14203	DCTN1	O14965	AURKA	S417	E415D	415	Missense	proximal	-2	no	28.830	40.814	EPSD	TCGA;COSMIC	39.062	Gain
Other_Aur_AURKA_ST	Q14203	DCTN1	O14965	AURKA	S586	R583Q	583	Missense	distal	-3	no	45.471	35.807	EPSD	TCGA;COSMIC	39.062	Loss
Other_Aur_AURKA_ST	Q14203	DCTN1	O14965	AURKA	S974	R972W	972	Missense	proximal	-2	no	45.307	-141.401	EPSD	TCGA;COSMIC	39.062	Loss
Other_Aur_AURKA_ST	Q14203	DCTN1	O14965	AURKA	S974	R972Q	972	Missense	proximal	-2	no	45.307	34.668	EPSD	TCGA;COSMIC	39.062	Loss
Other_Aur_AURKA_ST	Q14203	DCTN1	O14965	AURKA	S974	E968G	968	Missense	distal	-6	no	45.307	45.684	EPSD	TCGA	39.062	Up-regulation
Other_Aur_AURKA_ST	Q14203	DCTN1	O14965	AURKA	S974	K978N	978	Missense	distal	4	no	45.307	43.988	EPSD	TCGA	39.062	Down-regulation
Other_Aur_AURKA_ST	Q14203	DCTN1	O14965	AURKA	T1152	Q1154H	1154	Missense	proximal	2	no	43.089	39.984	EPSD	TCGA;COSMIC	39.062	Down-regulation
Other_Aur_AURKA_ST	Q14203	DCTN1	O14965	AURKA	T1152	Q1154L	1154	Missense	proximal	2	no	43.089	41.316	EPSD	TCGA;COSMIC	39.062	Down-regulation
Other_Aur_AURKA_ST	Q14203	DCTN1	O14965	AURKA	T1152	K1151E	1151	Missense	proximal	-1	no	43.089	42.669	EPSD	TCGA;COSMIC	39.062	Down-regulation
Other_Aur_AURKA_ST	Q14203	DCTN1	O14965	AURKA	T1152	R1150C	1150	Missense	proximal	-2	no	43.089	27.792	EPSD	TCGA;COSMIC;GDSC;CCLE	39.062	Loss
Other_Aur_AURKA_ST	Q14203	DCTN1	O14965	AURKA	T1152	R1150H	1150	Missense	proximal	-2	no	43.089	35.851	EPSD	TCGA	39.062	Loss
Other_Aur_AURKA_ST	Q14203	DCTN1	O14965	AURKA	S1153	Q1154H	1154	Missense	proximal	1	no	56.697	53.817	EPSD	TCGA;COSMIC	39.062	Down-regulation
Other_Aur_AURKA_ST	Q14203	DCTN1	O14965	AURKA	S1153	Q1154L	1154	Missense	proximal	1	no	56.697	58.236	EPSD	TCGA;COSMIC	39.062	Up-regulation
Other_Aur_AURKA_ST	Q14203	DCTN1	O14965	AURKA	S1153	K1151E	1151	Missense	proximal	-2	no	56.697	42.554	EPSD	TCGA;COSMIC	39.062	Down-regulation
Other_Aur_AURKA_ST	Q14203	DCTN1	O14965	AURKA	S1153	R1150C	1150	Missense	distal	-3	no	56.697	52.160	EPSD	TCGA;COSMIC;GDSC;CCLE	39.062	Down-regulation
Other_Aur_AURKA_ST	Q14203	DCTN1	O14965	AURKA	S1153	R1150H	1150	Missense	distal	-3	no	56.697	50.924	EPSD	TCGA	39.062	Down-regulation
Other_Aur_AURKA_ST	P00352	ALDH1A1	O14965	AURKA	S207	S207Y	207	Missense	central	0	yes	53.109	0.000	EPSD	TCGA;ICGC	39.062	Loss
Other_Aur_AURKA_ST	P46937	YAP1	O14965	AURKA	S61	S61W	61	Missense	central	0	yes	41.251	0.000	EPSD	TCGA;ICGC;COSMIC	39.062	Loss
Other_Aur_AURKA_ST	P46937	YAP1	O14965	AURKA	T77	V72I	72	Missense	distal	-5	no	41.891	41.894	EPSD	TCGA;ICGC;COSMIC	39.062	Up-regulation
Other_Aur_AURKA_ST	P46937	YAP1	O14965	AURKA	S94	F95C	95	Missense	proximal	1	no	40.709	32.315	EPSD	TCGA;ICGC	39.062	Loss
Other_Aur_AURKA_ST	P46937	YAP1	O14965	AURKA	T110	R106Q	106	Missense	distal	-4	no	39.541	39.694	EPSD	TCGA;ICGC;COSMIC;CCLE	39.062	Up-regulation
Other_Aur_AURKA_ST	P46937	YAP1	O14965	AURKA	T110	S109N	109	Missense	proximal	-1	no	39.541	37.701	EPSD	TCGA;ICGC;COSMIC	39.062	Loss
Other_Aur_AURKA_ST	P46937	YAP1	O14965	AURKA	S127	P129S	129	Missense	proximal	2	no	37.857	39.104	EPSD	TCGA;ICGC;COSMIC	39.062	Gain
Other_Aur_AURKA_ST	P46937	YAP1	O14965	AURKA	S128	G135E	135	Missense	distal	7	no	39.989	39.918	EPSD	TCGA;ICGC;COSMIC	39.062	Down-regulation
Other_Aur_AURKA_ST	P46937	YAP1	O14965	AURKA	S128	Q121H	121	Missense	distal	-7	no	39.989	39.036	EPSD	TCGA;ICGC;COSMIC	39.062	Loss
Other_Aur_AURKA_ST	P46937	YAP1	O14965	AURKA	S128	P129S	129	Missense	proximal	1	no	39.989	38.989	EPSD	TCGA;ICGC;COSMIC	39.062	Loss
Other_Aur_AURKA_ST	P46937	YAP1	O14965	AURKA	S128	R124P	124	Missense	distal	-4	no	39.989	38.873	EPSD	TCGA;ICGC;COSMIC	39.062	Loss
Other_Aur_AURKA_ST	P46937	YAP1	O14965	AURKA	S128	R124Q	124	Missense	distal	-4	no	39.989	40.143	EPSD	TCGA;ICGC;COSMIC	39.062	Up-regulation
Other_Aur_AURKA_ST	P46937	YAP1	O14965	AURKA	S163	Q158H	158	Missense	distal	-5	no	46.607	46.561	EPSD	TCGA;ICGC;COSMIC	39.062	Down-regulation
Other_Aur_AURKA_ST	P46937	YAP1	O14965	AURKA	S163	I167M	167	Missense	distal	4	no	46.607	46.899	EPSD	TCGA;ICGC	39.062	Up-regulation
Other_Aur_AURKA_ST	P46937	YAP1	O14965	AURKA	S164	Q158H	158	Missense	distal	-6	no	45.881	44.578	EPSD	TCGA;ICGC;COSMIC	39.062	Down-regulation
Other_Aur_AURKA_ST	P46937	YAP1	O14965	AURKA	S164	I167M	167	Missense	distal	3	no	45.881	45.327	EPSD	TCGA;ICGC	39.062	Down-regulation
Other_Aur_AURKA_ST	P46937	YAP1	O14965	AURKA	S274	S276N	276	Missense	proximal	2	no	51.592	51.026	EPSD	TCGA;ICGC	39.062	Down-regulation
Other_Aur_AURKA_ST	P46937	YAP1	O14965	AURKA	S274	A268G	268	Missense	distal	-6	no	51.592	48.615	EPSD	TCGA;ICGC;COSMIC	39.062	Down-regulation
Other_Aur_AURKA_ST	P46937	YAP1	O14965	AURKA	S274	Q275H	275	Missense	proximal	1	no	51.592	48.713	EPSD	TCGA;ICGC;COSMIC	39.062	Down-regulation
Other_Aur_AURKA_ST	P46937	YAP1	O14965	AURKA	S371	S366C	366	Missense	distal	-5	no	40.084	40.211	EPSD	TCGA	39.062	Up-regulation
Other_Aur_AURKA_ST	P46937	YAP1	O14965	AURKA	S371	G369R	369	Missense	proximal	-2	no	40.084	50.227	EPSD	TCGA;ICGC	39.062	Up-regulation
Other_Aur_AURKA_ST	P46937	YAP1	O14965	AURKA	S397	E396D	396	Missense	proximal	-1	no	44.220	46.321	PhosphoSitePlus	TCGA;ICGC;COSMIC	39.062	Up-regulation
Other_Aur_AURKA_ST	P46937	YAP1	O14965	AURKA	S419	E422D	422	Missense	distal	3	no	40.480	41.525	EPSD	TCGA;COSMIC	39.062	Up-regulation
Other_Aur_AURKA_ST	P46937	YAP1	O14965	AURKA	S419	P413Q	413	Missense	distal	-6	no	40.480	41.193	EPSD	TCGA;ICGC;COSMIC	39.062	Up-regulation
Other_Aur_AURKA_ST	Q92974	ARHGEF2	O14965	AURKA	T103	A97V	97	Missense	distal	-6	no	39.405	38.569	EPSD	TCGA;ICGC;COSMIC	39.062	Loss
Other_Aur_AURKA_ST	Q92974	ARHGEF2	O14965	AURKA	T103	A96T	96	Missense	distal	-7	no	39.405	38.947	EPSD	TCGA	39.062	Loss
Other_Aur_AURKA_ST	Q92974	ARHGEF2	O14965	AURKA	S133	R139H	139	Missense	distal	6	no	39.533	39.537	EPSD	TCGA;ICGC;COSMIC	39.062	Up-regulation
Other_Aur_AURKA_ST	Q92974	ARHGEF2	O14965	AURKA	S133	P126S	126	Missense	distal	-7	no	39.533	37.673	EPSD	TCGA;COSMIC	39.062	Loss
Other_Aur_AURKA_ST	Q92974	ARHGEF2	O14965	AURKA	S133	S133F	133	Missense	central	0	yes	39.533	0.000	EPSD	TCGA;COSMIC	39.062	Loss
Other_Aur_AURKA_ST	Q92974	ARHGEF2	O14965	AURKA	S142	R139H	139	Missense	distal	-3	no	47.482	41.709	EPSD	TCGA;ICGC;COSMIC	39.062	Down-regulation
Other_Aur_AURKA_ST	Q92974	ARHGEF2	O14965	AURKA	S143	R139H	139	Missense	distal	-4	no	47.935	43.500	EPSD	TCGA;ICGC;COSMIC	39.062	Down-regulation
Other_Aur_AURKA_ST	Q92974	ARHGEF2	O14965	AURKA	S186	R183Q	183	Missense	distal	-3	no	42.760	33.096	EPSD	TCGA;COSMIC	39.062	Loss
Other_Aur_AURKA_ST	Q92974	ARHGEF2	O14965	AURKA	S186	T184I	184	Missense	proximal	-2	no	42.760	42.944	EPSD	TCGA;COSMIC	39.062	Up-regulation
Other_Aur_AURKA_ST	Q92974	ARHGEF2	O14965	AURKA	S309	P307H	307	Missense	proximal	-2	no	33.818	41.639	EPSD	TCGA;COSMIC	39.062	Gain
Other_Aur_AURKA_ST	Q92974	ARHGEF2	O14965	AURKA	T392	Q389H	389	Missense	distal	-3	no	36.364	40.254	EPSD	TCGA	39.062	Gain
Other_Aur_AURKA_ST	Q92974	ARHGEF2	O14965	AURKA	S648	R650C	650	Missense	proximal	2	no	38.466	41.619	EPSD	TCGA;COSMIC;CCLE	39.062	Gain
Other_Aur_AURKA_ST	Q92974	ARHGEF2	O14965	AURKA	S648	R653Q	653	Missense	distal	5	no	38.466	40.846	EPSD	TCGA;COSMIC	39.062	Gain
Other_Aur_AURKA_ST	Q92974	ARHGEF2	O14965	AURKA	S696	P697L	697	Missense	proximal	1	no	43.927	48.577	EPSD	TCGA;COSMIC	39.062	Up-regulation
Other_Aur_AURKA_ST	Q92974	ARHGEF2	O14965	AURKA	S696	P697A	697	Missense	proximal	1	no	43.927	47.848	EPSD	TCGA;COSMIC	39.062	Up-regulation
Other_Aur_AURKA_ST	Q92974	ARHGEF2	O14965	AURKA	S696	T695M	695	Missense	proximal	-1	no	43.927	42.344	EPSD	TCGA;COSMIC	39.062	Down-regulation
Other_Aur_AURKA_ST	Q92974	ARHGEF2	O14965	AURKA	S733	P734L	734	Missense	proximal	1	no	45.168	49.818	EPSD	TCGA	39.062	Up-regulation
Other_Aur_AURKA_ST	Q92974	ARHGEF2	O14965	AURKA	S733	A738V	738	Missense	distal	5	no	45.168	44.552	EPSD	TCGA;COSMIC	39.062	Down-regulation
Other_Aur_AURKA_ST	Q92974	ARHGEF2	O14965	AURKA	S886	A889T	889	Missense	distal	3	no	55.637	54.505	PhosphoSitePlus	TCGA;COSMIC	39.062	Down-regulation
Other_Aur_AURKA_ST	Q92974	ARHGEF2	O14965	AURKA	S886	D891N	891	Missense	distal	5	no	55.637	54.314	PhosphoSitePlus	TCGA;COSMIC	39.062	Down-regulation
Other_Aur_AURKA_ST	Q92974	ARHGEF2	O14965	AURKA	S886	R885H	885	Missense	proximal	-1	no	55.637	55.228	PhosphoSitePlus	TCGA;COSMIC	39.062	Down-regulation
Other_Aur_AURKA_ST	Q92974	ARHGEF2	O14965	AURKA	S886	R883W	883	Missense	distal	-3	no	55.637	-23.535	PhosphoSitePlus	TCGA;COSMIC	39.062	Loss
Other_Aur_AURKA_ST	Q92974	ARHGEF2	O14965	AURKA	S903	S896R	896	Missense	distal	-7	no	38.848	39.422	EPSD	TCGA;COSMIC	39.062	Gain
Other_Aur_AURKA_ST	Q92974	ARHGEF2	O14965	AURKA	S956	S953R	953	Missense	distal	-3	no	42.134	48.613	EPSD	TCGA;COSMIC	39.062	Up-regulation
Other_Aur_AURKA_ST	Q92974	ARHGEF2	O14965	AURKA	S956	R954H	954	Missense	proximal	-2	no	42.134	34.895	EPSD	TCGA;COSMIC	39.062	Loss
Other_Aur_AURKA_ST	Q92974	ARHGEF2	O14965	AURKA	S956	R954C	954	Missense	proximal	-2	no	42.134	26.836	EPSD	TCGA;COSMIC	39.062	Loss
Other_Aur_AURKA_ST	Q92974	ARHGEF2	O14965	AURKA	S956	S960N	960	Missense	distal	4	no	42.134	41.259	EPSD	TCGA;COSMIC	39.062	Down-regulation
Other_Aur_AURKA_ST	P38398	BRCA1	O14965	AURKA	S184	S184C	184	Missense	central	0	yes	40.926	0.000	EPSD	TCGA;ICGC;COSMIC	39.062	Loss
Other_Aur_AURKA_ST	P38398	BRCA1	O14965	AURKA	S184	E181D	181	Missense	distal	-3	no	40.926	39.800	EPSD	TCGA;ICGC;COSMIC	39.062	Down-regulation
Other_Aur_AURKA_ST	P38398	BRCA1	O14965	AURKA	S308	E303K	303	Missense	distal	-5	no	41.070	41.051	PhosphoSitePlus	TCGA;COSMIC	39.062	Down-regulation
Other_Aur_AURKA_ST	P38398	BRCA1	O14965	AURKA	S308	A314T	314	Missense	distal	6	no	41.070	40.965	PhosphoSitePlus	TCGA	39.062	Down-regulation
Other_Aur_AURKA_ST	P38398	BRCA1	O14965	AURKA	S324	W321C	321	Missense	distal	-3	no	-33.857	40.778	EPSD	TCGA;COSMIC	39.062	Gain
Other_Aur_AURKA_ST	P38398	BRCA1	O14965	AURKA	S378	N383S	383	Missense	distal	5	no	41.436	41.825	EPSD	TCGA;COSMIC	39.062	Up-regulation
Other_Aur_AURKA_ST	P38398	BRCA1	O14965	AURKA	S395	E402K	402	Missense	distal	7	no	41.795	41.684	EPSD	TCGA;COSMIC	39.062	Down-regulation
Other_Aur_AURKA_ST	P38398	BRCA1	O14965	AURKA	S398	E402K	402	Missense	distal	4	no	41.810	41.794	EPSD	TCGA;COSMIC	39.062	Down-regulation
Other_Aur_AURKA_ST	P38398	BRCA1	O14965	AURKA	S449	R446T	446	Missense	distal	-3	no	47.447	37.831	EPSD	TCGA;COSMIC	39.062	Loss
Other_Aur_AURKA_ST	P38398	BRCA1	O14965	AURKA	T509	E515Q	515	Missense	distal	6	no	43.947	43.945	EPSD	TCGA;COSMIC	39.062	Down-regulation
Other_Aur_AURKA_ST	P38398	BRCA1	O14965	AURKA	T509	E515V	515	Missense	distal	6	no	43.947	43.918	EPSD	TCGA;COSMIC	39.062	Down-regulation
Other_Aur_AURKA_ST	P38398	BRCA1	O14965	AURKA	T509	E515K	515	Missense	distal	6	no	43.947	43.780	EPSD	TCGA;COSMIC	39.062	Down-regulation
Other_Aur_AURKA_ST	P38398	BRCA1	O14965	AURKA	T509	H513Y	513	Missense	distal	4	no	43.947	43.560	EPSD	TCGA;COSMIC	39.062	Down-regulation
Other_Aur_AURKA_ST	P38398	BRCA1	O14965	AURKA	S615	R610M	610	Missense	distal	-5	no	46.957	46.971	EPSD	TCGA;COSMIC	39.062	Up-regulation
Other_Aur_AURKA_ST	P38398	BRCA1	O14965	AURKA	S615	A622V	622	Missense	distal	7	no	46.957	47.085	EPSD	TCGA;COSMIC	39.062	Up-regulation
Other_Aur_AURKA_ST	P38398	BRCA1	O14965	AURKA	T710	G707R	707	Missense	distal	-3	no	37.739	42.933	EPSD	TCGA;COSMIC	39.062	Gain
Other_Aur_AURKA_ST	P38398	BRCA1	O14965	AURKA	S868	P871S	871	Missense	distal	3	no	42.885	43.537	EPSD	TCGA;COSMIC	39.062	Up-regulation
Other_Aur_AURKA_ST	P38398	BRCA1	O14965	AURKA	S868	S873L	873	Missense	distal	5	no	42.885	41.640	EPSD	TCGA;COSMIC	39.062	Down-regulation
Other_Aur_AURKA_ST	P38398	BRCA1	O14965	AURKA	S868	P875S	875	Missense	distal	7	no	42.885	42.995	EPSD	TCGA;COSMIC	39.062	Up-regulation
Other_Aur_AURKA_ST	P38398	BRCA1	O14965	AURKA	S868	R866C	866	Missense	proximal	-2	no	42.885	27.588	EPSD	TCGA;COSMIC	39.062	Loss
Other_Aur_AURKA_ST	P38398	BRCA1	O14965	AURKA	S1097	G1100R	1100	Missense	distal	3	no	46.272	45.614	EPSD	TCGA;COSMIC	39.062	Down-regulation
Other_Aur_AURKA_ST	P38398	BRCA1	O14965	AURKA	S1097	S1101R	1101	Missense	distal	4	no	46.272	45.741	EPSD	TCGA	39.062	Down-regulation
Other_Aur_AURKA_ST	P38398	BRCA1	O14965	AURKA	S1143	H1141R	1141	Missense	proximal	-2	no	42.911	50.150	EPSD	TCGA	39.062	Up-regulation
Other_Aur_AURKA_ST	P38398	BRCA1	O14965	AURKA	S1211	E1210Q	1210	Missense	proximal	-1	no	40.404	40.832	EPSD	TCGA;COSMIC	39.062	Up-regulation
Other_Aur_AURKA_ST	P38398	BRCA1	O14965	AURKA	S1211	E1214D	1214	Missense	distal	3	no	40.404	41.449	EPSD	TCGA;COSMIC	39.062	Up-regulation
Other_Aur_AURKA_ST	P38398	BRCA1	O14965	AURKA	S1211	S1211F	1211	Missense	central	0	yes	40.404	0.000	EPSD	TCGA;COSMIC	39.062	Loss
Other_Aur_AURKA_ST	P38398	BRCA1	O14965	AURKA	S1211	K1207N	1207	Missense	distal	-4	no	40.404	40.048	EPSD	TCGA;COSMIC	39.062	Down-regulation
Other_Aur_AURKA_ST	P38398	BRCA1	O14965	AURKA	S1211	L1216V	1216	Missense	distal	5	no	40.404	40.733	EPSD	TCGA;COSMIC	39.062	Up-regulation
Other_Aur_AURKA_ST	P38398	BRCA1	O14965	AURKA	T1246	V1247I	1247	Missense	proximal	1	no	43.578	41.015	EPSD	TCGA;COSMIC	39.062	Down-regulation
Other_Aur_AURKA_ST	P38398	BRCA1	O14965	AURKA	T1246	T1242A	1242	Missense	distal	-4	no	43.578	38.620	EPSD	TCGA;COSMIC	39.062	Loss
Other_Aur_AURKA_ST	P38398	BRCA1	O14965	AURKA	T1246	H1244N	1244	Missense	proximal	-2	no	43.578	40.335	EPSD	TCGA;COSMIC	39.062	Down-regulation
Other_Aur_AURKA_ST	P38398	BRCA1	O14965	AURKA	T1246	E1250K	1250	Missense	distal	4	no	43.578	43.563	EPSD	TCGA;COSMIC;GDSC	39.062	Down-regulation
Other_Aur_AURKA_ST	P38398	BRCA1	O14965	AURKA	S1262	E1258D	1258	Missense	distal	-4	no	40.323	36.101	EPSD	TCGA;COSMIC	39.062	Loss
Other_Aur_AURKA_ST	P38398	BRCA1	O14965	AURKA	S1262	E1258G	1258	Missense	distal	-4	no	40.323	38.487	EPSD	TCGA;COSMIC	39.062	Loss
Other_Aur_AURKA_ST	P38398	BRCA1	O14965	AURKA	S1262	L1261V	1261	Missense	proximal	-1	no	40.323	40.734	EPSD	TCGA;COSMIC	39.062	Up-regulation
Other_Aur_AURKA_ST	P38398	BRCA1	O14965	AURKA	S1497	G1492R	1492	Missense	distal	-5	no	46.425	46.445	EPSD	TCGA;COSMIC	39.062	Up-regulation
Other_Aur_AURKA_ST	P12755	SKI	O14965	AURKA	S325	R323Q	323	Missense	proximal	-2	no	51.752	41.113	EPSD	TCGA;ICGC;COSMIC	39.062	Down-regulation
Other_Aur_AURKA_ST	P12755	SKI	O14965	AURKA	S326	R323Q	323	Missense	distal	-3	no	47.043	37.379	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	39.062	Loss
Other_Aur_AURKA_ST	P12755	SKI	O14965	AURKA	S347	P344H	344	Missense	distal	-3	no	40.452	43.339	EPSD	TCGA	39.062	Up-regulation
Other_Aur_AURKA_ST	P12755	SKI	O14965	AURKA	S347	A345T	345	Missense	proximal	-2	no	40.452	32.877	EPSD	TCGA;ICGC;COSMIC	39.062	Loss
Other_Aur_AURKA_ST	P12755	SKI	O14965	AURKA	S366	R373H	373	Missense	distal	7	no	42.403	42.409	EPSD	TCGA;ICGC;COSMIC	39.062	Up-regulation
Other_Aur_AURKA_ST	P12755	SKI	O14965	AURKA	S377	S383F	383	Missense	distal	6	no	40.998	41.143	EPSD	TCGA;ICGC;COSMIC	39.062	Up-regulation
Other_Aur_AURKA_ST	P12755	SKI	O14965	AURKA	S377	R375H	375	Missense	proximal	-2	no	40.998	33.759	EPSD	TCGA;ICGC;COSMIC	39.062	Loss
Other_Aur_AURKA_ST	P12755	SKI	O14965	AURKA	S377	R373H	373	Missense	distal	-4	no	40.998	36.563	EPSD	TCGA;ICGC;COSMIC	39.062	Loss
Other_Aur_AURKA_ST	P12755	SKI	O14965	AURKA	S383	S383F	383	Missense	central	0	yes	50.892	0.000	PhosphoSitePlus;EPSD	TCGA;ICGC;COSMIC	39.062	Loss
Other_Aur_AURKA_ST	P12755	SKI	O14965	AURKA	S383	A385T	385	Missense	proximal	2	no	50.892	49.632	PhosphoSitePlus;EPSD	TCGA;ICGC;COSMIC	39.062	Down-regulation
Other_Aur_AURKA_ST	P12755	SKI	O14965	AURKA	S404	S410T	410	Missense	distal	6	no	42.731	42.634	EPSD	TCGA;ICGC;COSMIC	39.062	Down-regulation
Other_Aur_AURKA_ST	P12755	SKI	O14965	AURKA	T458	P462T	462	Missense	distal	4	no	42.601	41.639	EPSD	TCGA;ICGC;COSMIC	39.062	Down-regulation
Other_Aur_AURKA_ST	Q9BQG0	MYBBP1A	O14965	AURKA	S672	R671Q	671	Missense	proximal	-1	no	46.627	46.286	EPSD	TCGA;ICGC;COSMIC	39.062	Down-regulation
Other_Aur_AURKA_ST	Q9BQG0	MYBBP1A	O14965	AURKA	S983	L982P	982	Missense	proximal	-1	no	41.187	42.542	EPSD	TCGA;ICGC;COSMIC	39.062	Up-regulation
Other_Aur_AURKA_ST	Q9BQG0	MYBBP1A	O14965	AURKA	S983	N990Y	990	Missense	distal	7	no	41.187	41.346	EPSD	TCGA;ICGC;COSMIC	39.062	Up-regulation
Other_Aur_AURKA_ST	Q9BQG0	MYBBP1A	O14965	AURKA	S983	R989H	989	Missense	distal	6	no	41.187	41.191	EPSD	TCGA;ICGC	39.062	Up-regulation
Other_Aur_AURKA_ST	Q9BQG0	MYBBP1A	O14965	AURKA	S1186	D1188Y	1188	Missense	proximal	2	no	42.983	42.999	EPSD	TCGA;ICGC;COSMIC	39.062	Up-regulation
Other_Aur_AURKA_ST	Q9BQG0	MYBBP1A	O14965	AURKA	S1303	S1310N	1310	Missense	distal	7	no	51.884	51.805	PhosphoSitePlus	TCGA;ICGC;COSMIC	39.062	Down-regulation
Other_Aur_AURKA_ST	Q9BQG0	MYBBP1A	O14965	AURKA	S1303	P1309T	1309	Missense	distal	6	no	51.884	51.843	PhosphoSitePlus	TCGA;ICGC;COSMIC	39.062	Down-regulation
Other_Aur_AURKA_ST	P49841	GSK3B	O14965	AURKA	S215	Y216C	216	Missense	proximal	1	no	40.204	34.213	EPSD	TCGA;ICGC;COSMIC	39.062	Loss
Other_Aur_AURKA_ST	P49841	GSK3B	O14965	AURKA	S215	S215L	215	Missense	central	0	yes	40.204	0.000	EPSD	TCGA;ICGC;COSMIC	39.062	Loss
Other_Aur_AURKA_ST	Q9HC77	CENPJ	O14965	AURKA	S405	D409N	409	Missense	distal	4	no	40.458	39.376	EPSD	TCGA;ICGC;COSMIC	39.062	Down-regulation
Other_Aur_AURKA_ST	Q9HC77	CENPJ	O14965	AURKA	S405	P411L	411	Missense	distal	6	no	40.458	40.451	EPSD	TCGA;ICGC;COSMIC	39.062	Down-regulation
Other_Aur_AURKA_ST	Q9HC77	CENPJ	O14965	AURKA	S405	N403I	403	Missense	proximal	-2	no	40.458	31.911	EPSD	TCGA;ICGC;COSMIC	39.062	Loss
Other_Aur_AURKA_ST	Q9HC77	CENPJ	O14965	AURKA	S405	N403S	403	Missense	proximal	-2	no	40.458	37.782	EPSD	TCGA;ICGC;COSMIC	39.062	Loss
Other_Aur_AURKA_ST	Q9HC77	CENPJ	O14965	AURKA	S405	E408K	408	Missense	distal	3	no	40.458	39.062	EPSD	TCGA;ICGC;COSMIC	39.062	Down-regulation
Other_Aur_AURKA_ST	Q9HC77	CENPJ	O14965	AURKA	S467	L468I	468	Missense	proximal	1	no	46.849	43.376	PhosphoSitePlus	TCGA;ICGC;COSMIC	39.062	Down-regulation
Other_Aur_AURKA_ST	Q9HC77	CENPJ	O14965	AURKA	S529	G522V	522	Missense	distal	-7	no	43.885	45.215	EPSD	TCGA;ICGC	39.062	Up-regulation
Other_Aur_AURKA_ST	Q9HC77	CENPJ	O14965	AURKA	S529	G531R	531	Missense	proximal	2	no	43.885	42.514	EPSD	TCGA;ICGC;COSMIC	39.062	Down-regulation
Other_Aur_AURKA_ST	Q9HC77	CENPJ	O14965	AURKA	S529	P532L	532	Missense	distal	3	no	43.885	43.421	EPSD	TCGA;ICGC;COSMIC	39.062	Down-regulation
Other_Aur_AURKA_ST	Q9HC77	CENPJ	O14965	AURKA	T643	R645C	645	Missense	proximal	2	no	36.112	39.266	EPSD	TCGA;ICGC;COSMIC	39.062	Gain
Other_Aur_AURKA_ST	Q9HC77	CENPJ	O14965	AURKA	S660	L667F	667	Missense	distal	7	no	39.799	39.848	EPSD	TCGA;ICGC;COSMIC	39.062	Up-regulation
Other_Aur_AURKA_ST	Q9HC77	CENPJ	O14965	AURKA	S717	R721T	721	Missense	distal	4	no	41.443	40.959	EPSD	TCGA;ICGC;COSMIC	39.062	Down-regulation
Other_Aur_AURKA_ST	Q9HC77	CENPJ	O14965	AURKA	S717	R723G	723	Missense	distal	6	no	41.443	41.459	EPSD	TCGA;ICGC;COSMIC	39.062	Up-regulation
Other_Aur_AURKA_ST	Q9HC77	CENPJ	O14965	AURKA	S717	T713I	713	Missense	distal	-4	no	41.443	33.736	EPSD	TCGA;ICGC	39.062	Loss
Other_Aur_AURKA_ST	Q9HC77	CENPJ	O14965	AURKA	S717	V712A	712	Missense	distal	-5	no	41.443	41.417	EPSD	TCGA;ICGC;COSMIC	39.062	Down-regulation
Other_Aur_AURKA_ST	Q9HC77	CENPJ	O14965	AURKA	S784	V777A	777	Missense	distal	-7	no	39.720	39.588	EPSD	TCGA;ICGC;COSMIC	39.062	Down-regulation
Other_Aur_AURKA_ST	Q9HC77	CENPJ	O14965	AURKA	S857	R855T	855	Missense	proximal	-2	no	52.074	32.861	EPSD	TCGA;ICGC;COSMIC	39.062	Loss
Other_Aur_AURKA_ST	Q9HC77	CENPJ	O14965	AURKA	S857	R858I	858	Missense	proximal	1	no	52.074	51.031	EPSD	TCGA;ICGC	39.062	Down-regulation
Other_Aur_AURKA_ST	Q9HC77	CENPJ	O14965	AURKA	S857	R856K	856	Missense	proximal	-1	no	52.074	51.726	EPSD	TCGA;ICGC	39.062	Down-regulation
Other_Aur_AURKA_ST	Q9BT25	HAUS8	O14965	AURKA	S69	M62L	62	Missense	distal	-7	no	41.742	41.611	EPSD	TCGA;ICGC;COSMIC	39.062	Down-regulation
Other_Aur_AURKA_ST	Q9BT25	HAUS8	O14965	AURKA	S69	L72P	72	Missense	distal	3	no	41.742	42.206	EPSD	TCGA;ICGC;COSMIC	39.062	Up-regulation
Other_Aur_AURKA_ST	Q9BT25	HAUS8	O14965	AURKA	S70	L72P	72	Missense	proximal	2	no	44.480	44.211	EPSD	TCGA;ICGC;COSMIC	39.062	Down-regulation
Other_Aur_AURKA_ST	Q9BT25	HAUS8	O14965	AURKA	S139	P140L	140	Missense	proximal	1	no	35.363	40.013	EPSD	TCGA	39.062	Gain
Other_Aur_AURKA_ST	P40337	VHL	O14965	AURKA	S72	S65W	65	Missense	distal	-7	no	46.918	44.192	PhosphoSitePlus	TCGA;ICGC;COSMIC;CCLE	39.062	Down-regulation
Other_Aur_AURKA_ST	P40337	VHL	O14965	AURKA	S72	V74D	74	Missense	proximal	2	no	46.918	48.595	PhosphoSitePlus	TCGA;ICGC;COSMIC	39.062	Up-regulation
Other_Aur_AURKA_ST	P40337	VHL	O14965	AURKA	S72	N78D	78	Missense	distal	6	no	46.918	47.324	PhosphoSitePlus	TCGA;ICGC;COSMIC	39.062	Up-regulation
Other_Aur_AURKA_ST	P40337	VHL	O14965	AURKA	S72	N78Y	78	Missense	distal	6	no	46.918	47.105	PhosphoSitePlus	TCGA;ICGC;COSMIC	39.062	Up-regulation
Other_Aur_AURKA_ST	P40337	VHL	O14965	AURKA	S72	R79G	79	Missense	distal	7	no	46.918	47.055	PhosphoSitePlus	TCGA;ICGC;COSMIC	39.062	Up-regulation
Other_Aur_AURKA_ST	P40337	VHL	O14965	AURKA	S111	R113Q	113	Missense	proximal	2	no	44.644	46.644	EPSD	TCGA;ICGC;COSMIC	39.062	Up-regulation
Other_Aur_AURKA_ST	P40337	VHL	O14965	AURKA	S111	H115N	115	Missense	distal	4	no	44.644	43.631	EPSD	TCGA;COSMIC	39.062	Down-regulation
Other_Aur_AURKA_ST	P40337	VHL	O14965	AURKA	S111	R107P	107	Missense	distal	-4	no	44.644	43.527	EPSD	TCGA;ICGC;COSMIC	39.062	Down-regulation
Other_Aur_AURKA_ST	P40337	VHL	O14965	AURKA	S111	L118P	118	Missense	distal	7	no	44.644	44.560	EPSD	TCGA;ICGC;COSMIC	39.062	Down-regulation
Other_Aur_AURKA_ST	P40337	VHL	O14965	AURKA	S111	H110P	110	Missense	proximal	-1	no	44.644	44.850	EPSD	TCGA;ICGC;COSMIC;GDSC	39.062	Up-regulation
Other_Aur_AURKA_ST	P40337	VHL	O14965	AURKA	S111	H115Y	115	Missense	distal	4	no	44.644	44.257	EPSD	TCGA;COSMIC;GDSC;CCLE	39.062	Down-regulation
Other_Aur_AURKA_ST	P40337	VHL	O14965	AURKA	S111	S111N	111	Missense	central	0	yes	44.644	0.000	EPSD	TCGA;ICGC;COSMIC;CCLE	39.062	Loss
Other_Aur_AURKA_ST	P40337	VHL	O14965	AURKA	S111	W117C	117	Missense	distal	6	no	44.644	44.263	EPSD	TCGA;ICGC;COSMIC	39.062	Down-regulation
Other_Aur_AURKA_ST	P40337	VHL	O14965	AURKA	S111	L118F	118	Missense	distal	7	no	44.644	44.692	EPSD	TCGA;ICGC;COSMIC	39.062	Up-regulation
Other_Aur_AURKA_ST	P40337	VHL	O14965	AURKA	S168	V165D	165	Missense	distal	-3	no	46.126	40.798	EPSD	TCGA;COSMIC	39.062	Down-regulation
Other_Aur_AURKA_ST	P40337	VHL	O14965	AURKA	S168	L169P	169	Missense	proximal	1	no	46.126	41.476	EPSD	TCGA;ICGC;COSMIC	39.062	Down-regulation
Other_Aur_AURKA_ST	P40337	VHL	O14965	AURKA	S168	R161P	161	Missense	distal	-7	no	46.126	47.413	EPSD	TCGA;COSMIC	39.062	Up-regulation
Other_Aur_AURKA_ST	P40337	VHL	O14965	AURKA	S168	C162R	162	Missense	distal	-6	no	46.126	53.174	EPSD	TCGA;COSMIC	39.062	Up-regulation
Other_Aur_AURKA_ST	P40337	VHL	O14965	AURKA	S168	R167G	167	Missense	proximal	-1	no	46.126	46.197	EPSD	TCGA;COSMIC	39.062	Up-regulation
Other_Aur_AURKA_ST	P40337	VHL	O14965	AURKA	S168	R161Q	161	Missense	distal	-7	no	46.126	45.604	EPSD	TCGA;COSMIC	39.062	Down-regulation
Other_Aur_AURKA_ST	P40337	VHL	O14965	AURKA	S168	R167W	167	Missense	proximal	-1	no	46.126	49.801	EPSD	TCGA;ICGC;COSMIC	39.062	Up-regulation
Other_Aur_AURKA_ST	P40337	VHL	O14965	AURKA	S183	D190Y	190	Missense	distal	7	no	46.047	46.055	EPSD	TCGA;COSMIC	39.062	Up-regulation
Other_Aur_AURKA_ST	P40337	VHL	O14965	AURKA	S183	L188R	188	Missense	distal	5	no	46.047	46.140	EPSD	TCGA;COSMIC	39.062	Up-regulation
Other_Aur_AURKA_ST	P40337	VHL	O14965	AURKA	S183	L184P	184	Missense	proximal	1	no	46.047	41.397	EPSD	TCGA;COSMIC	39.062	Down-regulation
Other_Aur_AURKA_ST	P40337	VHL	O14965	AURKA	S183	L188P	188	Missense	distal	5	no	46.047	46.631	EPSD	TCGA;ICGC;COSMIC	39.062	Up-regulation
Other_Aur_AURKA_ST	P40337	VHL	O14965	AURKA	S183	L178P	178	Missense	distal	-5	no	46.047	46.035	EPSD	TCGA;COSMIC	39.062	Down-regulation
Other_Aur_AURKA_ST	P53671	LIMK2	O14965	AURKA	S319	I325V	325	Missense	distal	6	no	39.346	39.185	EPSD	TCGA;COSMIC;GDSC	39.062	Down-regulation
Other_Aur_AURKA_ST	P53671	LIMK2	O14965	AURKA	S322	I325V	325	Missense	distal	3	no	41.378	39.370	EPSD	TCGA;COSMIC;GDSC	39.062	Down-regulation
Other_Aur_AURKA_ST	Q8TEW0	PARD3	O14965	AURKA	S143	P146L	146	Missense	distal	3	no	44.529	44.066	EPSD	TCGA;ICGC;COSMIC	39.062	Down-regulation
Other_Aur_AURKA_ST	Q8TEW0	PARD3	O14965	AURKA	S144	P146L	146	Missense	proximal	2	no	55.088	55.357	EPSD	TCGA;ICGC;COSMIC	39.062	Up-regulation
Other_Aur_AURKA_ST	Q8TEW0	PARD3	O14965	AURKA	S174	P170S	170	Missense	distal	-4	no	44.902	46.819	EPSD	TCGA;ICGC;COSMIC	39.062	Up-regulation
Other_Aur_AURKA_ST	Q8TEW0	PARD3	O14965	AURKA	S174	R172C	172	Missense	proximal	-2	no	44.902	29.605	EPSD	TCGA;ICGC;COSMIC	39.062	Loss
Other_Aur_AURKA_ST	Q8TEW0	PARD3	O14965	AURKA	S383	S386I	386	Missense	distal	3	no	42.101	42.533	EPSD	TCGA;ICGC;COSMIC	39.062	Up-regulation
Other_Aur_AURKA_ST	Q8TEW0	PARD3	O14965	AURKA	T401	R407Q	407	Missense	distal	6	no	39.537	39.493	EPSD	TCGA;ICGC	39.062	Down-regulation
Other_Aur_AURKA_ST	Q8TEW0	PARD3	O14965	AURKA	S485	V490E	490	Missense	distal	5	no	41.134	42.058	EPSD	TCGA;ICGC;COSMIC	39.062	Up-regulation
Other_Aur_AURKA_ST	Q8TEW0	PARD3	O14965	AURKA	S533	S529L	529	Missense	distal	-4	no	40.374	39.609	EPSD	TCGA;ICGC;COSMIC;GDSC;CCLE	39.062	Down-regulation
Other_Aur_AURKA_ST	Q8TEW0	PARD3	O14965	AURKA	S533	T539N	539	Missense	distal	6	no	40.374	40.214	EPSD	TCGA;ICGC	39.062	Down-regulation
Other_Aur_AURKA_ST	Q8TEW0	PARD3	O14965	AURKA	S598	D595N	595	Missense	distal	-3	no	40.677	45.332	EPSD	TCGA;ICGC;COSMIC	39.062	Up-regulation
Other_Aur_AURKA_ST	Q8TEW0	PARD3	O14965	AURKA	S598	L601F	601	Missense	distal	3	no	40.677	41.847	EPSD	TCGA;ICGC;COSMIC	39.062	Up-regulation
Other_Aur_AURKA_ST	Q8TEW0	PARD3	O14965	AURKA	S665	S667C	667	Missense	proximal	2	no	42.295	44.243	EPSD	TCGA;ICGC;COSMIC	39.062	Up-regulation
Other_Aur_AURKA_ST	Q8TEW0	PARD3	O14965	AURKA	S715	D709N	709	Missense	distal	-6	no	46.088	52.108	EPSD	TCGA;ICGC;COSMIC	39.062	Up-regulation
Other_Aur_AURKA_ST	Q8TEW0	PARD3	O14965	AURKA	S715	R710K	710	Missense	distal	-5	no	46.088	46.062	EPSD	TCGA;ICGC;COSMIC	39.062	Down-regulation
Other_Aur_AURKA_ST	Q8TEW0	PARD3	O14965	AURKA	S715	R712Q	712	Missense	distal	-3	no	46.088	36.424	EPSD	TCGA;ICGC;COSMIC	39.062	Loss
Other_Aur_AURKA_ST	Q8TEW0	PARD3	O14965	AURKA	S715	G721R	721	Missense	distal	6	no	46.088	46.071	EPSD	TCGA;ICGC;COSMIC	39.062	Down-regulation
Other_Aur_AURKA_ST	Q8TEW0	PARD3	O14965	AURKA	S715	D708G	708	Missense	distal	-7	no	46.088	45.047	EPSD	TCGA;ICGC;COSMIC	39.062	Down-regulation
Other_Aur_AURKA_ST	Q8TEW0	PARD3	O14965	AURKA	T833	R832H	832	Missense	proximal	-1	no	45.157	44.747	EPSD	TCGA;COSMIC	39.062	Down-regulation
Other_Aur_AURKA_ST	Q8TEW0	PARD3	O14965	AURKA	S850	G856S	856	Missense	distal	6	no	45.306	45.307	EPSD	TCGA;COSMIC	39.062	Up-regulation
Other_Aur_AURKA_ST	Q8TEW0	PARD3	O14965	AURKA	S850	K849T	849	Missense	proximal	-1	no	45.306	47.367	EPSD	TCGA;COSMIC	39.062	Up-regulation
Other_Aur_AURKA_ST	Q8TEW0	PARD3	O14965	AURKA	S873	D867N	867	Missense	distal	-6	no	36.357	42.377	EPSD	TCGA;COSMIC	39.062	Gain
Other_Aur_AURKA_ST	Q8TEW0	PARD3	O14965	AURKA	S881	S881F	881	Missense	central	0	yes	43.757	0.000	EPSD	TCGA;COSMIC	39.062	Loss
Other_Aur_AURKA_ST	Q8TEW0	PARD3	O14965	AURKA	S881	K885N	885	Missense	distal	4	no	43.757	42.438	EPSD	TCGA	39.062	Down-regulation
Other_Aur_AURKA_ST	Q8TEW0	PARD3	O14965	AURKA	S888	S889T	889	Missense	proximal	1	no	40.545	43.793	EPSD	TCGA;COSMIC	39.062	Up-regulation
Other_Aur_AURKA_ST	Q8TEW0	PARD3	O14965	AURKA	S888	S881F	881	Missense	distal	-7	no	40.545	40.376	EPSD	TCGA;COSMIC	39.062	Down-regulation
Other_Aur_AURKA_ST	Q8TEW0	PARD3	O14965	AURKA	S888	K885N	885	Missense	distal	-3	no	40.545	42.535	EPSD	TCGA	39.062	Up-regulation
Other_Aur_AURKA_ST	Q8TEW0	PARD3	O14965	AURKA	S892	S889T	889	Missense	distal	-3	no	40.397	37.260	EPSD	TCGA;COSMIC	39.062	Loss
Other_Aur_AURKA_ST	Q8TEW0	PARD3	O14965	AURKA	S892	A896T	896	Missense	distal	4	no	40.397	39.349	EPSD	TCGA;COSMIC	39.062	Down-regulation
Other_Aur_AURKA_ST	Q8TEW0	PARD3	O14965	AURKA	S892	K885N	885	Missense	distal	-7	no	40.397	40.099	EPSD	TCGA	39.062	Down-regulation
Other_Aur_AURKA_ST	Q8TEW0	PARD3	O14965	AURKA	S962	S962Y	962	Missense	central	0	yes	46.913	0.000	PhosphoSitePlus	TCGA	39.062	Loss
Other_Aur_AURKA_ST	Q8TEW0	PARD3	O14965	AURKA	S964	S962Y	962	Missense	proximal	-2	no	41.899	41.181	EPSD	TCGA	39.062	Down-regulation
Other_Aur_AURKA_ST	Q8TEW0	PARD3	O14965	AURKA	S1046	S1046F	1046	Missense	central	0	yes	42.732	0.000	EPSD	TCGA;COSMIC	39.062	Loss
Other_Aur_AURKA_ST	Q8TEW0	PARD3	O14965	AURKA	S1046	E1052K	1052	Missense	distal	6	no	42.732	42.566	EPSD	TCGA;COSMIC	39.062	Down-regulation
Other_Aur_AURKA_ST	Q8TEW0	PARD3	O14965	AURKA	S1136	S1143G	1143	Missense	distal	7	no	48.417	48.536	EPSD	TCGA;COSMIC	39.062	Up-regulation
Other_Aur_AURKA_ST	Q8TEW0	PARD3	O14965	AURKA	S1136	R1134W	1134	Missense	proximal	-2	no	48.417	-138.291	EPSD	TCGA;COSMIC	39.062	Loss
Other_Aur_AURKA_ST	Q8TEW0	PARD3	O14965	AURKA	S1136	R1134Q	1134	Missense	proximal	-2	no	48.417	37.777	EPSD	TCGA;COSMIC	39.062	Loss
Other_Aur_AURKA_ST	Q8TEW0	PARD3	O14965	AURKA	S1139	S1143G	1143	Missense	distal	4	no	43.696	43.975	EPSD	TCGA;COSMIC	39.062	Up-regulation
Other_Aur_AURKA_ST	Q8TEW0	PARD3	O14965	AURKA	S1139	R1134W	1134	Missense	distal	-5	no	43.696	43.750	EPSD	TCGA;COSMIC	39.062	Up-regulation
Other_Aur_AURKA_ST	Q8TEW0	PARD3	O14965	AURKA	S1139	R1134Q	1134	Missense	distal	-5	no	43.696	43.686	EPSD	TCGA;COSMIC	39.062	Down-regulation
Other_Aur_AURKA_ST	Q8TEW0	PARD3	O14965	AURKA	T1147	S1143G	1143	Missense	distal	-4	no	45.841	44.721	EPSD	TCGA;COSMIC	39.062	Down-regulation
Other_Aur_AURKA_ST	Q8TEW0	PARD3	O14965	AURKA	T1147	R1153L	1153	Missense	distal	6	no	45.841	45.795	EPSD	TCGA;COSMIC	39.062	Down-regulation
Other_Aur_AURKA_ST	Q8TEW0	PARD3	O14965	AURKA	T1147	R1153W	1153	Missense	distal	6	no	45.841	46.050	EPSD	TCGA;COSMIC;GDSC;CCLE	39.062	Up-regulation
Other_Aur_AURKA_ST	Q8TEW0	PARD3	O14965	AURKA	T1147	R1153Q	1153	Missense	distal	6	no	45.841	45.797	EPSD	TCGA;COSMIC	39.062	Down-regulation
Other_Aur_AURKA_ST	Q8TEW0	PARD3	O14965	AURKA	T1176	Q1181E	1181	Missense	distal	5	no	47.137	45.916	EPSD	TCGA;COSMIC	39.062	Down-regulation
Other_Aur_AURKA_ST	Q8TEW0	PARD3	O14965	AURKA	T1176	R1173C	1173	Missense	distal	-3	no	47.137	42.600	EPSD	TCGA;COSMIC	39.062	Down-regulation
Other_Aur_AURKA_ST	Q8TEW0	PARD3	O14965	AURKA	T1176	E1180Q	1180	Missense	distal	4	no	47.137	46.560	EPSD	TCGA;COSMIC	39.062	Down-regulation
Other_Aur_AURKA_ST	Q8TEW0	PARD3	O14965	AURKA	T1176	E1180D	1180	Missense	distal	4	no	47.137	46.885	EPSD	TCGA;COSMIC	39.062	Down-regulation
Other_Aur_AURKA_ST	Q8TEW0	PARD3	O14965	AURKA	T1176	R1175W	1175	Missense	proximal	-1	no	47.137	50.812	EPSD	TCGA;COSMIC	39.062	Up-regulation
Other_Aur_AURKA_ST	Q8TEW0	PARD3	O14965	AURKA	T1176	F1179L	1179	Missense	distal	3	no	47.137	45.967	EPSD	TCGA	39.062	Down-regulation
Other_Aur_AURKA_ST	Q8TEW0	PARD3	O14965	AURKA	S1196	S1198F	1198	Missense	proximal	2	no	52.969	52.273	EPSD	TCGA;COSMIC	39.062	Down-regulation
Other_Aur_AURKA_ST	Q8TEW0	PARD3	O14965	AURKA	S1196	Q1191H	1191	Missense	distal	-5	no	52.969	52.923	EPSD	TCGA;COSMIC;CCLE	39.062	Down-regulation
Other_Aur_AURKA_ST	Q8TEW0	PARD3	O14965	AURKA	S1196	S1196L	1196	Missense	central	0	yes	52.969	0.000	EPSD	TCGA	39.062	Loss
Other_Aur_AURKA_ST	Q8TEW0	PARD3	O14965	AURKA	S1196	V1199A	1199	Missense	distal	3	no	52.969	53.091	EPSD	TCGA;COSMIC	39.062	Up-regulation
Other_Aur_AURKA_ST	Q8TEW0	PARD3	O14965	AURKA	S1196	H1195Y	1195	Missense	proximal	-1	no	52.969	52.446	EPSD	TCGA;COSMIC	39.062	Down-regulation
Other_Aur_AURKA_ST	Q8TEW0	PARD3	O14965	AURKA	S1196	A1189V	1189	Missense	distal	-7	no	52.969	53.101	EPSD	TCGA	39.062	Up-regulation
Other_Aur_AURKA_ST	Q8TEW0	PARD3	O14965	AURKA	S1222	R1219H	1219	Missense	distal	-3	no	42.703	36.930	EPSD	TCGA;COSMIC	39.062	Loss
Other_Aur_AURKA_ST	Q8TEW0	PARD3	O14965	AURKA	S1236	D1238E	1238	Missense	proximal	2	no	41.394	40.624	EPSD	TCGA;COSMIC	39.062	Down-regulation
Other_Aur_AURKA_ST	Q8TEW0	PARD3	O14965	AURKA	S1236	S1239Y	1239	Missense	distal	3	no	41.394	41.381	EPSD	TCGA;COSMIC	39.062	Down-regulation
Other_Aur_AURKA_ST	Q8TEW0	PARD3	O14965	AURKA	S1236	S1236F	1236	Missense	central	0	yes	41.394	0.000	EPSD	TCGA;COSMIC	39.062	Loss
Other_Aur_AURKA_ST	Q8TEW0	PARD3	O14965	AURKA	S1236	A1232V	1232	Missense	distal	-4	no	41.394	45.069	EPSD	TCGA;COSMIC	39.062	Up-regulation
Other_Aur_AURKA_ST	Q8TEW0	PARD3	O14965	AURKA	S1236	D1238H	1238	Missense	proximal	2	no	41.394	37.858	EPSD	TCGA	39.062	Loss
Other_Aur_AURKA_ST	Q8NHV4	NEDD1	O14965	AURKA	S389	T387R	387	Missense	proximal	-2	no	25.561	44.774	EPSD	TCGA;COSMIC	39.062	Gain
Other_Aur_AURKA_ST	Q8NHV4	NEDD1	O14965	AURKA	S405	S411G	411	Missense	distal	6	no	46.873	46.871	PhosphoSitePlus	TCGA;COSMIC	39.062	Down-regulation
Other_Aur_AURKA_ST	P53350	PLK1	O14965	AURKA	S137	R134H	134	Missense	distal	-3	no	50.188	44.415	EPSD	TCGA;ICGC	39.062	Down-regulation
Other_Aur_AURKA_ST	P53350	PLK1	O14965	AURKA	T210	G213V	213	Missense	distal	3	no	45.299	44.129	PhosphoSitePlus	TCGA;ICGC	39.062	Down-regulation
Other_Aur_AURKA_ST	P53350	PLK1	O14965	AURKA	T210	K208E	208	Missense	proximal	-2	no	45.299	31.156	PhosphoSitePlus	TCGA;ICGC;COSMIC	39.062	Loss
Other_Aur_AURKA_ST	P53350	PLK1	O14965	AURKA	T210	D204G	204	Missense	distal	-6	no	45.299	45.353	PhosphoSitePlus	TCGA;ICGC;COSMIC	39.062	Up-regulation
Other_Aur_AURKA_ST	P53350	PLK1	O14965	AURKA	S326	L319M	319	Missense	distal	-7	no	44.780	44.911	EPSD	TCGA;ICGC;COSMIC	39.062	Up-regulation
Other_Aur_AURKA_ST	P53350	PLK1	O14965	AURKA	S326	S326L	326	Missense	central	0	yes	44.780	0.000	EPSD	TCGA;ICGC;COSMIC;CCLE	39.062	Loss
Other_Aur_AURKA_ST	P53350	PLK1	O14965	AURKA	S326	P323L	323	Missense	distal	-3	no	44.780	45.923	EPSD	TCGA;ICGC;COSMIC	39.062	Up-regulation
Other_Aur_AURKA_ST	P53350	PLK1	O14965	AURKA	S375	V369A	369	Missense	distal	-6	no	39.292	40.128	EPSD	TCGA;ICGC;COSMIC	39.062	Up-regulation
Other_Aur_AURKA_ST	P03372	ESR1	O14965	AURKA	S46	Y52H	52	Missense	distal	6	no	39.630	39.685	EPSD	TCGA;ICGC;COSMIC	39.062	Up-regulation
Other_Aur_AURKA_ST	P03372	ESR1	O14965	AURKA	S46	E41D	41	Missense	distal	-5	no	39.630	39.649	EPSD	TCGA;ICGC;COSMIC	39.062	Up-regulation
Other_Aur_AURKA_ST	P03372	ESR1	O14965	AURKA	S46	G40V	40	Missense	distal	-6	no	39.630	41.771	EPSD	TCGA;ICGC;COSMIC	39.062	Up-regulation
Other_Aur_AURKA_ST	P03372	ESR1	O14965	AURKA	S154	P152T	152	Missense	proximal	-2	no	44.115	39.961	EPSD	TCGA;ICGC;COSMIC	39.062	Down-regulation
Other_Aur_AURKA_ST	P03372	ESR1	O14965	AURKA	S167	A166S	166	Missense	proximal	-1	no	51.493	51.381	PhosphoSitePlus;EPSD	TCGA;ICGC;COSMIC	39.062	Down-regulation
Other_Aur_AURKA_ST	P03372	ESR1	O14965	AURKA	S167	K171M	171	Missense	distal	4	no	51.493	51.928	PhosphoSitePlus;EPSD	TCGA;ICGC;COSMIC	39.062	Up-regulation
Other_Aur_AURKA_ST	P03372	ESR1	O14965	AURKA	S236	K235N	235	Missense	proximal	-1	no	39.350	37.870	EPSD	TCGA;ICGC;COSMIC	39.062	Loss
Other_Aur_AURKA_ST	P03372	ESR1	O14965	AURKA	S236	A239S	239	Missense	distal	3	no	39.350	40.805	EPSD	TCGA;ICGC;COSMIC	39.062	Up-regulation
Other_Aur_AURKA_ST	P03372	ESR1	O14965	AURKA	S236	R243H	243	Missense	distal	7	no	39.350	39.355	EPSD	TCGA;ICGC;COSMIC	39.062	Up-regulation
Other_Aur_AURKA_ST	P03372	ESR1	O14965	AURKA	S236	R243C	243	Missense	distal	7	no	39.350	39.391	EPSD	TCGA;ICGC;COSMIC	39.062	Up-regulation
Other_Aur_AURKA_ST	P03372	ESR1	O14965	AURKA	S236	C240Y	240	Missense	distal	4	no	39.350	39.659	EPSD	TCGA;ICGC;COSMIC	39.062	Up-regulation
Other_Aur_AURKA_ST	P03372	ESR1	O14965	AURKA	S294	W292R	292	Missense	proximal	-2	no	-144.509	42.199	EPSD	TCGA;ICGC;COSMIC	39.062	Gain
Other_Aur_AURKA_ST	P03372	ESR1	O14965	AURKA	S305	I298M	298	Missense	distal	-7	no	43.639	44.481	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	39.062	Up-regulation
Other_Aur_AURKA_ST	P03372	ESR1	O14965	AURKA	S305	A307S	307	Missense	proximal	2	no	43.639	45.523	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	39.062	Up-regulation
Other_Aur_AURKA_ST	P03372	ESR1	O14965	AURKA	S305	T311M	311	Missense	distal	6	no	43.639	43.805	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	39.062	Up-regulation
Other_Aur_AURKA_ST	P03372	ESR1	O14965	AURKA	S559	T563M	563	Missense	distal	4	no	46.323	48.217	EPSD	TCGA;ICGC;COSMIC	39.062	Up-regulation
Other_Aur_AURKA_ST	P03372	ESR1	O14965	AURKA	S559	R555C	555	Missense	distal	-4	no	46.323	43.123	EPSD	TCGA;ICGC;COSMIC	39.062	Down-regulation
Other_Aur_AURKA_ST	P03372	ESR1	O14965	AURKA	S559	R555H	555	Missense	distal	-4	no	46.323	41.888	EPSD	TCGA;ICGC;COSMIC;GDSC	39.062	Down-regulation
Other_Aur_AURKA_ST	P06748	NPM1	O14965	AURKA	S137	L136F	136	Missense	proximal	-1	no	39.719	42.361	EPSD	TCGA;ICGC;COSMIC	39.062	Up-regulation
Other_Aur_AURKA_ST	P06748	NPM1	O14965	AURKA	S137	I138V	138	Missense	proximal	1	no	39.719	42.283	EPSD	TCGA;ICGC;COSMIC;GDSC;CCLE	39.062	Up-regulation
Other_Aur_AURKA_ST	P06748	NPM1	O14965	AURKA	S143	L136F	136	Missense	distal	-7	no	49.237	48.881	EPSD	TCGA;ICGC;COSMIC	39.062	Down-regulation
Other_Aur_AURKA_ST	P06748	NPM1	O14965	AURKA	S143	I138V	138	Missense	distal	-5	no	49.237	49.234	EPSD	TCGA;ICGC;COSMIC;GDSC;CCLE	39.062	Down-regulation
Other_Aur_AURKA_ST	P06748	NPM1	O14965	AURKA	S143	G147D	147	Missense	distal	4	no	49.237	49.167	EPSD	TCGA;ICGC;COSMIC	39.062	Down-regulation
Other_Aur_AURKA_ST	P06748	NPM1	O14965	AURKA	S149	G147D	147	Missense	proximal	-2	no	38.691	40.172	EPSD	TCGA;ICGC;COSMIC	39.062	Gain
Other_Aur_AURKA_ST	P06748	NPM1	O14965	AURKA	S218	P216S	216	Missense	proximal	-2	no	37.520	39.421	EPSD	TCGA;ICGC;COSMIC	39.062	Gain
Other_Aur_AURKA_ST	P06748	NPM1	O14965	AURKA	S243	K239N	239	Missense	distal	-4	no	45.603	45.246	EPSD	TCGA;ICGC;COSMIC	39.062	Down-regulation
Other_Aur_AURKA_ST	P06748	NPM1	O14965	AURKA	S260	K257E	257	Missense	distal	-3	no	43.470	41.931	EPSD	TCGA;ICGC;COSMIC	39.062	Down-regulation
Other_Aur_AURKA_ST	P06748	NPM1	O14965	AURKA	S260	A266T	266	Missense	distal	6	no	43.470	43.365	EPSD	TCGA;ICGC	39.062	Down-regulation
Other_Aur_AURKA_ST	Q15398	DLGAP5	O14965	AURKA	T66	L60F	60	Missense	distal	-6	no	49.713	45.585	EPSD	TCGA;ICGC;COSMIC	39.062	Down-regulation
Other_Aur_AURKA_ST	Q15398	DLGAP5	O14965	AURKA	T66	P72L	72	Missense	distal	6	no	49.713	49.706	EPSD	TCGA;ICGC;COSMIC	39.062	Down-regulation
Other_Aur_AURKA_ST	Q15398	DLGAP5	O14965	AURKA	T66	Q68K	68	Missense	proximal	2	no	49.713	46.309	EPSD	TCGA	39.062	Down-regulation
Other_Aur_AURKA_ST	Q15398	DLGAP5	O14965	AURKA	T66	S67Y	67	Missense	proximal	1	no	49.713	53.790	EPSD	TCGA;ICGC;COSMIC	39.062	Up-regulation
Other_Aur_AURKA_ST	Q15398	DLGAP5	O14965	AURKA	T66	L60I	60	Missense	distal	-6	no	49.713	43.842	EPSD	TCGA;ICGC;COSMIC	39.062	Down-regulation
Other_Aur_AURKA_ST	Q15398	DLGAP5	O14965	AURKA	S188	K193Q	193	Missense	distal	5	no	40.319	41.013	EPSD	TCGA;ICGC;COSMIC	39.062	Up-regulation
Other_Aur_AURKA_ST	Q15398	DLGAP5	O14965	AURKA	T210	R207Q	207	Missense	distal	-3	no	43.258	33.595	EPSD	TCGA	39.062	Loss
Other_Aur_AURKA_ST	Q15398	DLGAP5	O14965	AURKA	S353	D351N	351	Missense	proximal	-2	no	48.549	46.729	EPSD	TCGA;ICGC;COSMIC	39.062	Down-regulation
Other_Aur_AURKA_ST	Q15398	DLGAP5	O14965	AURKA	S353	E349K	349	Missense	distal	-4	no	48.549	48.740	EPSD	TCGA;ICGC;COSMIC	39.062	Up-regulation
Other_Aur_AURKA_ST	Q15398	DLGAP5	O14965	AURKA	S353	S353F	353	Missense	central	0	yes	48.549	0.000	EPSD	TCGA	39.062	Loss
Other_Aur_AURKA_ST	Q15398	DLGAP5	O14965	AURKA	S353	A355S	355	Missense	proximal	2	no	48.549	50.433	EPSD	TCGA;ICGC;COSMIC	39.062	Up-regulation
Other_Aur_AURKA_ST	Q15398	DLGAP5	O14965	AURKA	S650	V647I	647	Missense	distal	-3	no	42.928	39.820	EPSD	TCGA;ICGC;COSMIC	39.062	Down-regulation
Other_Aur_AURKA_ST	Q15398	DLGAP5	O14965	AURKA	S650	V643A	643	Missense	distal	-7	no	42.928	42.795	EPSD	TCGA;ICGC;COSMIC	39.062	Down-regulation
Other_Aur_AURKA_ST	Q15398	DLGAP5	O14965	AURKA	S690	P697T	697	Missense	distal	7	no	42.807	42.852	EPSD	TCGA;ICGC;COSMIC	39.062	Up-regulation
Other_Aur_AURKA_ST	Q15398	DLGAP5	O14965	AURKA	S725	L728V	728	Missense	distal	3	no	49.847	49.386	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	39.062	Down-regulation
Other_Aur_AURKA_ST	Q15398	DLGAP5	O14965	AURKA	S725	R723K	723	Missense	proximal	-2	no	49.847	43.344	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	39.062	Down-regulation
Other_Aur_AURKA_ST	Q15398	DLGAP5	O14965	AURKA	S725	M724I	724	Missense	proximal	-1	no	49.847	51.222	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	39.062	Up-regulation
Other_Aur_AURKA_ST	Q15398	DLGAP5	O14965	AURKA	S725	P727S	727	Missense	proximal	2	no	49.847	51.095	EPSD;PhosphoSitePlus	TCGA;ICGC	39.062	Up-regulation
Other_Aur_AURKA_ST	Q15398	DLGAP5	O14965	AURKA	S725	S725G	725	Missense	central	0	yes	49.847	0.000	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	39.062	Loss
Other_Aur_AURKA_ST	Q15398	DLGAP5	O14965	AURKA	S757	S756Y	756	Missense	proximal	-1	no	43.830	42.886	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	39.062	Down-regulation
Other_Aur_AURKA_ST	Q13158	FADD	O14965	AURKA	S41	G42R	42	Missense	proximal	1	no	42.277	43.096	EPSD	TCGA	39.062	Up-regulation
Other_Aur_AURKA_ST	Q13158	FADD	O14965	AURKA	S41	L36P	36	Missense	distal	-5	no	42.277	42.264	EPSD	TCGA;ICGC;COSMIC	39.062	Down-regulation
Other_Aur_AURKA_ST	Q13158	FADD	O14965	AURKA	S69	S69F	69	Missense	central	0	yes	42.411	0.000	EPSD	TCGA;ICGC;COSMIC	39.062	Loss
Other_Aur_AURKA_ST	Q13158	FADD	O14965	AURKA	S69	D74Y	74	Missense	distal	5	no	42.411	41.530	EPSD	TCGA;ICGC;COSMIC	39.062	Down-regulation
Other_Aur_AURKA_ST	Q13158	FADD	O14965	AURKA	S69	R72H	72	Missense	distal	3	no	42.411	42.145	EPSD	TCGA;ICGC;COSMIC	39.062	Down-regulation
Other_Aur_AURKA_ST	Q9NRM7	LATS2	O14965	AURKA	S83	P86S	86	Missense	distal	3	no	49.494	50.146	PhosphoSitePlus;EPSD	TCGA;ICGC;COSMIC	39.062	Up-regulation
Other_Aur_AURKA_ST	Q9NRM7	LATS2	O14965	AURKA	S172	G175R	175	Missense	distal	3	no	62.398	61.739	EPSD	TCGA;ICGC;COSMIC	39.062	Down-regulation
Other_Aur_AURKA_ST	Q9NRM7	LATS2	O14965	AURKA	S172	P166S	166	Missense	distal	-6	no	62.398	62.947	EPSD	TCGA;ICGC;COSMIC	39.062	Up-regulation
Other_Aur_AURKA_ST	Q9NRM7	LATS2	O14965	AURKA	S172	T168M	168	Missense	distal	-4	no	62.398	59.578	EPSD	TCGA;ICGC;COSMIC	39.062	Down-regulation
Other_Aur_AURKA_ST	Q9NRM7	LATS2	O14965	AURKA	S274	P280L	280	Missense	distal	6	no	51.716	51.709	EPSD	TCGA;ICGC;COSMIC	39.062	Down-regulation
Other_Aur_AURKA_ST	Q9NRM7	LATS2	O14965	AURKA	S335	L331M	331	Missense	distal	-4	no	41.945	41.888	EPSD	TCGA;ICGC;COSMIC	39.062	Down-regulation
Other_Aur_AURKA_ST	Q9NRM7	LATS2	O14965	AURKA	S576	V580I	580	Missense	distal	4	no	45.265	46.111	EPSD	TCGA;ICGC;COSMIC	39.062	Up-regulation
Other_Aur_AURKA_ST	Q9NRM7	LATS2	O14965	AURKA	S576	R581C	581	Missense	distal	5	no	45.265	47.414	EPSD	TCGA;ICGC;COSMIC	39.062	Up-regulation
Other_Aur_AURKA_ST	Q9NRM7	LATS2	O14965	AURKA	S576	P577L	577	Missense	proximal	1	no	45.265	49.914	EPSD	TCGA;ICGC;COSMIC	39.062	Up-regulation
Other_Aur_AURKA_ST	Q9NRM7	LATS2	O14965	AURKA	S576	R581H	581	Missense	distal	5	no	45.265	45.773	EPSD	TCGA;ICGC	39.062	Up-regulation
Other_Aur_AURKA_ST	Q9NRM7	LATS2	O14965	AURKA	S576	I573F	573	Missense	distal	-3	no	45.265	41.439	EPSD	TCGA;ICGC;COSMIC	39.062	Down-regulation
Other_Aur_AURKA_ST	Q9NRM7	LATS2	O14965	AURKA	S835	R832G	832	Missense	distal	-3	no	49.319	44.125	EPSD	TCGA;ICGC;COSMIC	39.062	Down-regulation
Other_Aur_AURKA_ST	Q9NRM7	LATS2	O14965	AURKA	S835	Q833H	833	Missense	proximal	-2	no	49.319	52.719	EPSD	TCGA;ICGC;COSMIC	39.062	Up-regulation
Other_Aur_AURKA_ST	Q9NRM7	LATS2	O14965	AURKA	S835	L841F	841	Missense	distal	6	no	49.319	49.528	EPSD	TCGA;ICGC;COSMIC	39.062	Up-regulation
Other_Aur_AURKA_ST	O15350	TP73	O14965	AURKA	S223	S223L	223	Missense	central	0	yes	40.317	0.000	EPSD	TCGA;ICGC;COSMIC	39.062	Loss
Other_Aur_AURKA_ST	O15350	TP73	O14965	AURKA	S223	V230D	230	Missense	distal	7	no	40.317	40.315	EPSD	TCGA;ICGC;COSMIC	39.062	Down-regulation
Other_Aur_AURKA_ST	O15350	TP73	O14965	AURKA	S223	E218K	218	Missense	distal	-5	no	40.317	40.299	EPSD	TCGA;ICGC;COSMIC	39.062	Down-regulation
Other_Aur_AURKA_ST	O15350	TP73	O14965	AURKA	S235	G232A	232	Missense	distal	-3	no	53.827	51.129	PhosphoSitePlus	TCGA	39.062	Down-regulation
Other_Aur_AURKA_ST	O15350	TP73	O14965	AURKA	S235	V230D	230	Missense	distal	-5	no	53.827	53.849	PhosphoSitePlus	TCGA;ICGC;COSMIC	39.062	Up-regulation
Other_Aur_AURKA_ST	O15350	TP73	O14965	AURKA	S289	R293C	293	Missense	distal	4	no	54.533	54.507	EPSD	TCGA;ICGC;COSMIC	39.062	Down-regulation
Other_Aur_AURKA_ST	O15350	TP73	O14965	AURKA	S289	A296T	296	Missense	distal	7	no	54.533	54.523	EPSD	TCGA;ICGC;COSMIC	39.062	Down-regulation
Other_Aur_AURKA_ST	O15350	TP73	O14965	AURKA	S289	S289F	289	Missense	central	0	yes	54.533	0.000	EPSD	TCGA;ICGC;COSMIC	39.062	Loss
Other_Aur_AURKA_ST	O15350	TP73	O14965	AURKA	S289	R293S	293	Missense	distal	4	no	54.533	55.065	EPSD	TCGA;ICGC;COSMIC	39.062	Up-regulation
Other_Aur_AURKA_ST	O15350	TP73	O14965	AURKA	S471	A472T	472	Missense	proximal	1	no	40.632	38.960	EPSD	TCGA;COSMIC;GDSC;CCLE	39.062	Loss
Other_Aur_AURKA_ST	O14777	NDC80	O14965	AURKA	S44	P48L	48	Missense	distal	4	no	46.151	46.298	PhosphoSitePlus;EPSD	TCGA;ICGC;COSMIC	39.062	Up-regulation
Other_Aur_AURKA_ST	O14777	NDC80	O14965	AURKA	S44	E51K	51	Missense	distal	7	no	46.151	46.041	PhosphoSitePlus;EPSD	TCGA;ICGC;COSMIC	39.062	Down-regulation
Other_Aur_AURKA_ST	O14777	NDC80	O14965	AURKA	S44	F40L	40	Missense	distal	-4	no	46.151	49.435	PhosphoSitePlus;EPSD	TCGA;ICGC;COSMIC	39.062	Up-regulation
Other_Aur_AURKA_ST	O14777	NDC80	O14965	AURKA	S55	P48L	48	Missense	distal	-7	no	48.968	47.295	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	39.062	Down-regulation
Other_Aur_AURKA_ST	O14777	NDC80	O14965	AURKA	S55	E51K	51	Missense	distal	-4	no	48.968	49.159	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	39.062	Up-regulation
Other_Aur_AURKA_ST	O14777	NDC80	O14965	AURKA	S55	S62N	62	Missense	distal	7	no	48.968	48.889	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	39.062	Down-regulation
Other_Aur_AURKA_ST	O14777	NDC80	O14965	AURKA	S55	R52G	52	Missense	distal	-3	no	48.968	43.775	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	39.062	Down-regulation
Other_Aur_AURKA_ST	O14777	NDC80	O14965	AURKA	S66	S62N	62	Missense	distal	-4	no	40.871	41.421	EPSD	TCGA;ICGC;COSMIC	39.062	Up-regulation
Other_Aur_AURKA_ST	O14777	NDC80	O14965	AURKA	S66	R67W	67	Missense	proximal	1	no	40.871	38.298	EPSD	TCGA;ICGC;COSMIC	39.062	Loss
Other_Aur_AURKA_ST	O14777	NDC80	O14965	AURKA	S69	S62N	62	Missense	distal	-7	no	48.764	48.100	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	39.062	Down-regulation
Other_Aur_AURKA_ST	O14777	NDC80	O14965	AURKA	S69	R67W	67	Missense	proximal	-2	no	48.764	-137.944	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	39.062	Loss
Other_Aur_AURKA_ST	O95983	MBD3	O14965	AURKA	S39	K41N	41	Missense	proximal	2	no	38.461	40.505	EPSD	TCGA;ICGC;COSMIC	39.062	Gain
Other_Aur_AURKA_ST	O95983	MBD3	O14965	AURKA	S77	R82H	82	Missense	distal	5	no	39.538	40.046	EPSD	TCGA	39.062	Up-regulation
Other_Aur_AURKA_ST	O95983	MBD3	O14965	AURKA	S77	S77N	77	Missense	central	0	yes	39.538	0.000	EPSD	TCGA;ICGC;COSMIC;GDSC;CCLE	39.062	Loss
Other_Aur_AURKA_ST	O95983	MBD3	O14965	AURKA	S77	R80H	80	Missense	distal	3	no	39.538	39.272	EPSD	TCGA;COSMIC	39.062	Down-regulation
Other_Aur_AURKA_ST	O95983	MBD3	O14965	AURKA	S77	R82C	82	Missense	distal	5	no	39.538	41.688	EPSD	TCGA;CCLE	39.062	Up-regulation
Other_Aur_AURKA_ST	O95983	MBD3	O14965	AURKA	S77	R78H	78	Missense	proximal	1	no	39.538	37.550	EPSD	TCGA;COSMIC	39.062	Loss
Other_Aur_AURKA_ST	O95983	MBD3	O14965	AURKA	S85	N87S	87	Missense	proximal	2	no	47.557	48.123	PhosphoSitePlus;EPSD	TCGA;COSMIC	39.062	Up-regulation
Other_Aur_AURKA_ST	O95983	MBD3	O14965	AURKA	S85	R82H	82	Missense	distal	-3	no	47.557	41.784	PhosphoSitePlus;EPSD	TCGA	39.062	Down-regulation
Other_Aur_AURKA_ST	O95983	MBD3	O14965	AURKA	S85	S85F	85	Missense	central	0	yes	47.557	0.000	PhosphoSitePlus;EPSD	TCGA;COSMIC	39.062	Loss
Other_Aur_AURKA_ST	O95983	MBD3	O14965	AURKA	S85	R80H	80	Missense	distal	-5	no	47.557	47.501	PhosphoSitePlus;EPSD	TCGA;COSMIC	39.062	Down-regulation
Other_Aur_AURKA_ST	O95983	MBD3	O14965	AURKA	S85	R82C	82	Missense	distal	-3	no	47.557	43.020	PhosphoSitePlus;EPSD	TCGA;CCLE	39.062	Down-regulation
Other_Aur_AURKA_ST	O95983	MBD3	O14965	AURKA	S85	R78H	78	Missense	distal	-7	no	47.557	46.081	PhosphoSitePlus;EPSD	TCGA;COSMIC	39.062	Down-regulation
Other_Aur_AURKA_ST	O95983	MBD3	O14965	AURKA	S144	D150Y	150	Missense	distal	6	no	41.295	41.076	EPSD	TCGA;COSMIC	39.062	Down-regulation
Other_Aur_AURKA_ST	Q99708	RBBP8	O14965	AURKA	T241	P246L	246	Missense	distal	5	no	39.537	38.953	EPSD	TCGA;ICGC;COSMIC	39.062	Loss
Other_Aur_AURKA_ST	Q99708	RBBP8	O14965	AURKA	S242	P246L	246	Missense	distal	4	no	42.709	42.856	EPSD	TCGA;ICGC;COSMIC	39.062	Up-regulation
Other_Aur_AURKA_ST	Q99708	RBBP8	O14965	AURKA	S327	A332T	332	Missense	distal	5	no	46.400	47.031	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	39.062	Up-regulation
Other_Aur_AURKA_ST	Q99708	RBBP8	O14965	AURKA	T361	L362H	362	Missense	proximal	1	no	39.739	35.321	EPSD	TCGA;ICGC;COSMIC	39.062	Loss
Other_Aur_AURKA_ST	Q99708	RBBP8	O14965	AURKA	S428	D427H	427	Missense	proximal	-1	no	45.418	43.676	EPSD	TCGA;ICGC;COSMIC	39.062	Down-regulation
Other_Aur_AURKA_ST	Q99708	RBBP8	O14965	AURKA	S428	S428F	428	Missense	central	0	yes	45.418	0.000	EPSD	TCGA;ICGC;COSMIC	39.062	Loss
Other_Aur_AURKA_ST	Q99708	RBBP8	O14965	AURKA	S439	L437M	437	Missense	proximal	-2	no	44.122	36.013	EPSD	TCGA;ICGC;COSMIC	39.062	Loss
Other_Aur_AURKA_ST	Q99708	RBBP8	O14965	AURKA	T450	E451K	451	Missense	proximal	1	no	39.663	41.687	EPSD	TCGA;ICGC;COSMIC	39.062	Up-regulation
Other_Aur_AURKA_ST	Q99708	RBBP8	O14965	AURKA	T450	E453Q	453	Missense	distal	3	no	39.663	39.276	EPSD	TCGA;ICGC;COSMIC	39.062	Down-regulation
Other_Aur_AURKA_ST	Q99708	RBBP8	O14965	AURKA	T450	E455K	455	Missense	distal	5	no	39.663	40.191	EPSD	TCGA;ICGC;COSMIC	39.062	Up-regulation
Other_Aur_AURKA_ST	Q99708	RBBP8	O14965	AURKA	T596	E597D	597	Missense	proximal	1	no	37.177	39.393	EPSD	TCGA;ICGC;COSMIC;GDSC;CCLE	39.062	Gain
Other_Aur_AURKA_ST	Q49MG5	MAP9	O14965	AURKA	S180	R177Q	177	Missense	distal	-3	no	41.687	32.023	EPSD	TCGA;ICGC;COSMIC	39.062	Loss
Other_Aur_AURKA_ST	Q49MG5	MAP9	O14965	AURKA	S291	S289L	289	Missense	proximal	-2	no	42.006	45.443	EPSD	TCGA;ICGC;COSMIC	39.062	Up-regulation
Other_Aur_AURKA_ST	Q49MG5	MAP9	O14965	AURKA	S291	E287D	287	Missense	distal	-4	no	42.006	37.784	EPSD	TCGA;ICGC;COSMIC	39.062	Loss
Other_Aur_AURKA_ST	Q49MG5	MAP9	O14965	AURKA	S305	E300V	300	Missense	distal	-5	no	46.356	46.354	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	39.062	Down-regulation
Other_Aur_AURKA_ST	Q49MG5	MAP9	O14965	AURKA	S305	A309T	309	Missense	distal	4	no	46.356	45.308	EPSD;PhosphoSitePlus	TCGA;ICGC	39.062	Down-regulation
Other_Aur_AURKA_ST	Q49MG5	MAP9	O14965	AURKA	S363	N366D	366	Missense	distal	3	no	40.835	45.320	EPSD	TCGA;ICGC;COSMIC	39.062	Up-regulation
Other_Aur_AURKA_ST	Q49MG5	MAP9	O14965	AURKA	S363	S369F	369	Missense	distal	6	no	40.835	40.981	EPSD	TCGA;ICGC;COSMIC	39.062	Up-regulation
Other_Aur_AURKA_ST	Q49MG5	MAP9	O14965	AURKA	S363	K359N	359	Missense	distal	-4	no	40.835	40.478	EPSD	TCGA;ICGC;COSMIC	39.062	Down-regulation
Other_Aur_AURKA_ST	Q49MG5	MAP9	O14965	AURKA	S363	N365H	365	Missense	proximal	2	no	40.835	39.091	EPSD	TCGA	39.062	Down-regulation
Other_Aur_AURKA_ST	Q49MG5	MAP9	O14965	AURKA	S363	N357H	357	Missense	distal	-6	no	40.835	36.491	EPSD	TCGA;ICGC	39.062	Loss
Other_Aur_AURKA_ST	Q49MG5	MAP9	O14965	AURKA	S369	R374S	374	Missense	distal	5	no	38.490	39.642	EPSD	TCGA;ICGC;COSMIC	39.062	Gain
Other_Aur_AURKA_ST	Q49MG5	MAP9	O14965	AURKA	S370	A371T	371	Missense	proximal	1	no	39.850	38.178	EPSD	TCGA;ICGC;COSMIC	39.062	Loss
Other_Aur_AURKA_ST	Q49MG5	MAP9	O14965	AURKA	S370	N366D	366	Missense	distal	-4	no	39.850	35.794	EPSD	TCGA;ICGC;COSMIC	39.062	Loss
Other_Aur_AURKA_ST	Q49MG5	MAP9	O14965	AURKA	S370	S369F	369	Missense	proximal	-1	no	39.850	40.923	EPSD	TCGA;ICGC;COSMIC	39.062	Up-regulation
Other_Aur_AURKA_ST	Q49MG5	MAP9	O14965	AURKA	S370	A373V	373	Missense	distal	3	no	39.850	39.728	EPSD	TCGA;ICGC;COSMIC	39.062	Down-regulation
Other_Aur_AURKA_ST	Q49MG5	MAP9	O14965	AURKA	S370	R374S	374	Missense	distal	4	no	39.850	40.382	EPSD	TCGA;ICGC;COSMIC	39.062	Up-regulation
Other_Aur_AURKA_ST	Q49MG5	MAP9	O14965	AURKA	S370	N365H	365	Missense	distal	-5	no	39.850	39.750	EPSD	TCGA	39.062	Down-regulation
Other_Aur_AURKA_ST	Q49MG5	MAP9	O14965	AURKA	T377	A371T	371	Missense	distal	-6	no	39.173	38.952	EPSD	TCGA;ICGC;COSMIC	39.062	Loss
Other_Aur_AURKA_ST	Q49MG5	MAP9	O14965	AURKA	T377	S378C	378	Missense	proximal	1	no	39.173	37.259	EPSD	TCGA;ICGC;COSMIC	39.062	Loss
Other_Aur_AURKA_ST	Q49MG5	MAP9	O14965	AURKA	T377	A373V	373	Missense	distal	-4	no	39.173	42.848	EPSD	TCGA;ICGC;COSMIC	39.062	Up-regulation
Other_Aur_AURKA_ST	Q49MG5	MAP9	O14965	AURKA	T377	R374S	374	Missense	distal	-3	no	39.173	32.693	EPSD	TCGA;ICGC;COSMIC	39.062	Loss
Other_Aur_AURKA_ST	Q49MG5	MAP9	O14965	AURKA	S385	S378C	378	Missense	distal	-7	no	42.090	41.457	EPSD	TCGA;ICGC;COSMIC	39.062	Down-regulation
Other_Aur_AURKA_ST	Q49MG5	MAP9	O14965	AURKA	S385	S385G	385	Missense	central	0	yes	42.090	0.000	EPSD	TCGA;ICGC;COSMIC	39.062	Loss
Other_Aur_AURKA_ST	Q49MG5	MAP9	O14965	AURKA	S385	S386F	386	Missense	proximal	1	no	42.090	48.570	EPSD	TCGA;ICGC;COSMIC	39.062	Up-regulation
Other_Aur_AURKA_ST	Q49MG5	MAP9	O14965	AURKA	S625	E630K	630	Missense	distal	5	no	48.519	49.046	PhosphoSitePlus;EPSD	TCGA;ICGC;COSMIC	39.062	Up-regulation
Other_Aur_AURKA_ST	Q96EB6	SIRT1	O14965	AURKA	S169	E164K	164	Missense	distal	-5	no	39.321	39.302	EPSD	TCGA;ICGC;COSMIC	39.062	Down-regulation
Other_Aur_AURKA_ST	Q96EB6	SIRT1	O14965	AURKA	S562	D557N	557	Missense	distal	-5	no	40.601	40.632	EPSD	TCGA;COSMIC	39.062	Up-regulation
Other_Aur_AURKA_ST	Q96EB6	SIRT1	O14965	AURKA	S562	A559S	559	Missense	distal	-3	no	40.601	42.014	EPSD	TCGA	39.062	Up-regulation
Other_Aur_AURKA_ST	Q96EB6	SIRT1	O14965	AURKA	S606	E609A	609	Missense	distal	3	no	42.304	41.139	EPSD	TCGA;COSMIC	39.062	Down-regulation
Other_Aur_AURKA_ST	Q96EB6	SIRT1	O14965	AURKA	S659	A655T	655	Missense	distal	-4	no	40.032	44.991	EPSD	TCGA;COSMIC	39.062	Up-regulation
Other_Aur_AURKA_ST	Q96EB6	SIRT1	O14965	AURKA	S659	V665I	665	Missense	distal	6	no	40.032	40.193	EPSD	TCGA;COSMIC	39.062	Up-regulation
Other_Aur_AURKA_ST	Q96CX2	KCTD12	O14965	AURKA	S183	R184H	184	Missense	proximal	1	no	42.758	40.769	EPSD	TCGA;ICGC;COSMIC	39.062	Down-regulation
Other_Aur_AURKA_ST	Q96CX2	KCTD12	O14965	AURKA	S187	R184H	184	Missense	distal	-3	no	42.744	36.971	EPSD	TCGA;ICGC;COSMIC	39.062	Loss
Other_Aur_AURKA_ST	Q96CX2	KCTD12	O14965	AURKA	S217	Y218H	218	Missense	proximal	1	no	40.760	37.914	EPSD	TCGA;ICGC;COSMIC	39.062	Loss
Other_Aur_AURKA_ST	O43521	BCL2L11	O14965	AURKA	S35	G31E	31	Missense	distal	-4	no	38.267	40.102	EPSD	TCGA;ICGC;COSMIC	39.062	Gain
Other_Aur_AURKA_ST	O43521	BCL2L11	O14965	AURKA	S87	R91Q	91	Missense	distal	4	no	42.260	42.674	EPSD	TCGA;ICGC;COSMIC	39.062	Up-regulation
Other_Aur_AURKA_ST	O43521	BCL2L11	O14965	AURKA	S87	R85I	85	Missense	proximal	-2	no	42.260	23.231	EPSD	TCGA;ICGC;COSMIC	39.062	Loss
Other_Aur_AURKA_ST	O43521	BCL2L11	O14965	AURKA	S87	L88M	88	Missense	proximal	1	no	42.260	41.349	EPSD	TCGA;ICGC;COSMIC	39.062	Down-regulation
Other_Aur_AURKA_ST	O43521	BCL2L11	O14965	AURKA	S87	R84T	84	Missense	distal	-3	no	42.260	32.644	EPSD	TCGA;ICGC;COSMIC	39.062	Loss
Other_Aur_AURKA_ST	O43521	BCL2L11	O14965	AURKA	S90	R91Q	91	Missense	proximal	1	no	41.931	42.822	EPSD	TCGA;ICGC;COSMIC	39.062	Up-regulation
Other_Aur_AURKA_ST	O43521	BCL2L11	O14965	AURKA	S90	R85I	85	Missense	distal	-5	no	41.931	41.926	EPSD	TCGA;ICGC;COSMIC	39.062	Down-regulation
Other_Aur_AURKA_ST	O43521	BCL2L11	O14965	AURKA	S90	L88M	88	Missense	proximal	-2	no	41.931	33.822	EPSD	TCGA;ICGC;COSMIC	39.062	Loss
Other_Aur_AURKA_ST	O43521	BCL2L11	O14965	AURKA	S90	R84T	84	Missense	distal	-6	no	41.931	40.896	EPSD	TCGA;ICGC;COSMIC	39.062	Down-regulation
Other_Aur_AURKA_ST	O43521	BCL2L11	O14965	AURKA	S90	Y96C	96	Missense	distal	6	no	41.931	41.812	EPSD	TCGA;ICGC;COSMIC	39.062	Down-regulation
Other_Aur_AURKA_ST	O43521	BCL2L11	O14965	AURKA	S93	R91Q	91	Missense	proximal	-2	no	48.846	38.207	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	39.062	Loss
Other_Aur_AURKA_ST	O43521	BCL2L11	O14965	AURKA	S93	L88M	88	Missense	distal	-5	no	48.846	48.873	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	39.062	Up-regulation
Other_Aur_AURKA_ST	O43521	BCL2L11	O14965	AURKA	S93	Y96C	96	Missense	distal	3	no	48.846	46.521	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	39.062	Down-regulation
Other_Aur_AURKA_ST	O43521	BCL2L11	O14965	AURKA	S94	R91Q	91	Missense	distal	-3	no	49.381	39.718	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	39.062	Down-regulation
Other_Aur_AURKA_ST	O43521	BCL2L11	O14965	AURKA	S94	L88M	88	Missense	distal	-6	no	49.381	50.435	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	39.062	Up-regulation
Other_Aur_AURKA_ST	O43521	BCL2L11	O14965	AURKA	S94	Y96C	96	Missense	proximal	2	no	49.381	50.088	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	39.062	Up-regulation
Other_Aur_AURKA_ST	O43521	BCL2L11	O14965	AURKA	S98	R91Q	91	Missense	distal	-7	no	47.342	46.819	PhosphoSitePlus;EPSD	TCGA;ICGC;COSMIC	39.062	Down-regulation
Other_Aur_AURKA_ST	O43521	BCL2L11	O14965	AURKA	S98	Y96C	96	Missense	proximal	-2	no	47.342	45.921	PhosphoSitePlus;EPSD	TCGA;ICGC;COSMIC	39.062	Down-regulation
Other_Aur_AURKA_ST	Q14511	NEDD9	O14965	AURKA	T104	P101S	101	Missense	distal	-3	no	46.395	48.575	EPSD	TCGA;ICGC;COSMIC	39.062	Up-regulation
Other_Aur_AURKA_ST	Q14511	NEDD9	O14965	AURKA	T126	G125R	125	Missense	proximal	-1	no	40.028	39.957	EPSD	TCGA;ICGC;COSMIC	39.062	Down-regulation
Other_Aur_AURKA_ST	Q14511	NEDD9	O14965	AURKA	T126	G125D	125	Missense	proximal	-1	no	40.028	41.290	EPSD	TCGA;ICGC;COSMIC	39.062	Up-regulation
Other_Aur_AURKA_ST	Q14511	NEDD9	O14965	AURKA	T126	Q119E	119	Missense	distal	-7	no	40.028	38.967	EPSD	TCGA;ICGC;COSMIC	39.062	Loss
Other_Aur_AURKA_ST	Q14511	NEDD9	O14965	AURKA	T126	P121L	121	Missense	distal	-5	no	40.028	40.040	EPSD	TCGA;ICGC;COSMIC	39.062	Up-regulation
Other_Aur_AURKA_ST	Q14511	NEDD9	O14965	AURKA	S202	I208V	208	Missense	distal	6	no	42.491	42.330	EPSD	TCGA;ICGC;COSMIC	39.062	Down-regulation
Other_Aur_AURKA_ST	Q14511	NEDD9	O14965	AURKA	S296	S298F	298	Missense	proximal	2	no	48.185	47.489	PhosphoSitePlus	TCGA;ICGC;COSMIC	39.062	Down-regulation
Other_Aur_AURKA_ST	Q14511	NEDD9	O14965	AURKA	S375	S369P	369	Missense	distal	-6	no	42.041	41.491	EPSD	TCGA	39.062	Down-regulation
Other_Aur_AURKA_ST	Q9ULW0	TPX2	O14965	AURKA	S121	A115T	115	Missense	distal	-6	no	46.346	46.125	PhosphoSitePlus;EPSD	TCGA;ICGC;COSMIC	39.062	Down-regulation
Other_Aur_AURKA_ST	Q9ULW0	TPX2	O14965	AURKA	S125	Q132H	132	Missense	distal	7	no	55.518	55.580	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	39.062	Up-regulation
Other_Aur_AURKA_ST	Q9ULW0	TPX2	O14965	AURKA	T179	A184T	184	Missense	distal	5	no	38.597	39.229	EPSD	TCGA;ICGC;COSMIC	39.062	Gain
Other_Aur_AURKA_ST	Q9ULW0	TPX2	O14965	AURKA	S358	S359F	359	Missense	proximal	1	no	41.277	47.757	EPSD	TCGA;COSMIC	39.062	Up-regulation
Other_Aur_AURKA_ST	Q9ULW0	TPX2	O14965	AURKA	S358	K362N	362	Missense	distal	4	no	41.277	39.958	EPSD	TCGA;COSMIC	39.062	Down-regulation
Other_Aur_AURKA_ST	Q9ULW0	TPX2	O14965	AURKA	T499	D502Y	502	Missense	distal	3	no	40.933	40.165	EPSD	TCGA;COSMIC	39.062	Down-regulation
Other_Aur_AURKA_ST	Q9ULW0	TPX2	O14965	AURKA	T499	R494I	494	Missense	distal	-5	no	40.933	40.927	EPSD	TCGA	39.062	Down-regulation
Other_Aur_AURKA_ST	Q9UPY8	MAPRE3	O14965	AURKA	S176	V178M	178	Missense	proximal	2	no	52.054	51.762	PhosphoSitePlus	TCGA;COSMIC	39.062	Down-regulation
Other_Aur_AURKA_ST	Q9UPY8	MAPRE3	O14965	AURKA	S176	R174W	174	Missense	proximal	-2	no	52.054	-134.654	PhosphoSitePlus	TCGA;COSMIC	39.062	Loss
Other_Aur_AURKA_ST	P04637	TP53	O14965	AURKA	S106	G105C	105	Missense	proximal	-1	no	42.716	42.429	PhosphoSitePlus;EPSD	TCGA;ICGC;COSMIC;GDSC	39.062	Down-regulation
Other_Aur_AURKA_ST	P04637	TP53	O14965	AURKA	S106	R110L	110	Missense	distal	4	no	42.716	43.341	PhosphoSitePlus;EPSD	TCGA;ICGC;COSMIC;GDSC;CCLE	39.062	Up-regulation
Other_Aur_AURKA_ST	P04637	TP53	O14965	AURKA	S106	L111R	111	Missense	distal	5	no	42.716	42.808	PhosphoSitePlus;EPSD	TCGA;ICGC;COSMIC	39.062	Up-regulation
Other_Aur_AURKA_ST	P04637	TP53	O14965	AURKA	S106	L111P	111	Missense	distal	5	no	42.716	43.299	PhosphoSitePlus;EPSD	TCGA;ICGC;COSMIC	39.062	Up-regulation
Other_Aur_AURKA_ST	P04637	TP53	O14965	AURKA	S106	L111Q	111	Missense	distal	5	no	42.716	45.189	PhosphoSitePlus;EPSD	TCGA;ICGC;COSMIC	39.062	Up-regulation
Other_Aur_AURKA_ST	P04637	TP53	O14965	AURKA	S106	Y107D	107	Missense	proximal	1	no	42.716	42.715	PhosphoSitePlus;EPSD	TCGA;ICGC;COSMIC	39.062	Down-regulation
Other_Aur_AURKA_ST	P04637	TP53	O14965	AURKA	S106	F113V	113	Missense	distal	7	no	42.716	42.767	PhosphoSitePlus;EPSD	TCGA;ICGC;COSMIC;GDSC;CCLE	39.062	Up-regulation
Other_Aur_AURKA_ST	P04637	TP53	O14965	AURKA	S106	R110C	110	Missense	distal	4	no	42.716	42.690	PhosphoSitePlus;EPSD	TCGA;ICGC;COSMIC;GDSC;CCLE	39.062	Down-regulation
Other_Aur_AURKA_ST	P04637	TP53	O14965	AURKA	S106	S106R	106	Missense	central	0	yes	42.716	0.000	PhosphoSitePlus;EPSD	TCGA;ICGC;COSMIC;GDSC;CCLE	39.062	Loss
Other_Aur_AURKA_ST	P04637	TP53	O14965	AURKA	S106	F109S	109	Missense	distal	3	no	42.716	42.661	PhosphoSitePlus;EPSD	TCGA;ICGC;COSMIC	39.062	Down-regulation
Other_Aur_AURKA_ST	P04637	TP53	O14965	AURKA	S106	G105R	105	Missense	proximal	-1	no	42.716	42.645	PhosphoSitePlus;EPSD	TCGA;ICGC;COSMIC;CCLE	39.062	Down-regulation
Other_Aur_AURKA_ST	P04637	TP53	O14965	AURKA	S106	G105V	105	Missense	proximal	-1	no	42.716	41.498	PhosphoSitePlus;EPSD	TCGA;ICGC;COSMIC	39.062	Down-regulation
Other_Aur_AURKA_ST	P04637	TP53	O14965	AURKA	S106	F109V	109	Missense	distal	3	no	42.716	41.084	PhosphoSitePlus;EPSD	TCGA;ICGC;COSMIC	39.062	Down-regulation
Other_Aur_AURKA_ST	P04637	TP53	O14965	AURKA	S106	R110P	110	Missense	distal	4	no	42.716	43.194	PhosphoSitePlus;EPSD	TCGA;ICGC;COSMIC;GDSC;CCLE	39.062	Up-regulation
Other_Aur_AURKA_ST	P04637	TP53	O14965	AURKA	S106	G105D	105	Missense	proximal	-1	no	42.716	43.978	PhosphoSitePlus;EPSD	TCGA;ICGC;COSMIC	39.062	Up-regulation
Other_Aur_AURKA_ST	P04637	TP53	O14965	AURKA	S106	F109C	109	Missense	distal	3	no	42.716	40.323	PhosphoSitePlus;EPSD	TCGA;ICGC;COSMIC	39.062	Down-regulation
Other_Aur_AURKA_ST	P04637	TP53	O14965	AURKA	S106	G105S	105	Missense	proximal	-1	no	42.716	42.656	PhosphoSitePlus;EPSD	TCGA;ICGC;COSMIC	39.062	Down-regulation
Other_Aur_AURKA_ST	P04637	TP53	O14965	AURKA	S106	G108S	108	Missense	proximal	2	no	42.716	42.550	PhosphoSitePlus;EPSD	TCGA;ICGC;COSMIC	39.062	Down-regulation
Other_Aur_AURKA_ST	P04637	TP53	O14965	AURKA	S106	F113L	113	Missense	distal	7	no	42.716	42.667	PhosphoSitePlus;EPSD	TCGA;ICGC;COSMIC;GDSC;CCLE	39.062	Down-regulation
Other_Aur_AURKA_ST	P04637	TP53	O14965	AURKA	S149	W146S	146	Missense	distal	-3	no	-30.341	42.352	EPSD	TCGA;ICGC;COSMIC	39.062	Gain
Other_Aur_AURKA_ST	P04637	TP53	O14965	AURKA	S183	H179R	179	Missense	distal	-4	no	41.241	45.676	EPSD	TCGA;ICGC;COSMIC;GDSC;CCLE	39.062	Up-regulation
Other_Aur_AURKA_ST	P04637	TP53	O14965	AURKA	S183	C176F	176	Missense	distal	-7	no	41.241	41.705	EPSD	TCGA;ICGC;COSMIC;GDSC;CCLE	39.062	Up-regulation
Other_Aur_AURKA_ST	P04637	TP53	O14965	AURKA	S183	R181H	181	Missense	proximal	-2	no	41.241	34.002	EPSD	TCGA;ICGC;COSMIC;CCLE	39.062	Loss
Other_Aur_AURKA_ST	P04637	TP53	O14965	AURKA	S183	G187S	187	Missense	distal	4	no	41.241	40.963	EPSD	TCGA;ICGC;COSMIC	39.062	Down-regulation
Other_Aur_AURKA_ST	P04637	TP53	O14965	AURKA	S183	H179Y	179	Missense	distal	-4	no	41.241	46.530	EPSD	TCGA;ICGC;COSMIC	39.062	Up-regulation
Other_Aur_AURKA_ST	P04637	TP53	O14965	AURKA	S183	C176Y	176	Missense	distal	-7	no	41.241	42.061	EPSD	TCGA;ICGC;COSMIC;GDSC;CCLE	39.062	Up-regulation
Other_Aur_AURKA_ST	P04637	TP53	O14965	AURKA	S183	P190L	190	Missense	distal	7	no	41.241	41.324	EPSD	TCGA;ICGC;COSMIC;CCLE	39.062	Up-regulation
Other_Aur_AURKA_ST	P04637	TP53	O14965	AURKA	S183	P177S	177	Missense	distal	-6	no	41.241	41.791	EPSD	TCGA;ICGC;COSMIC	39.062	Up-regulation
Other_Aur_AURKA_ST	P04637	TP53	O14965	AURKA	S183	H178Q	178	Missense	distal	-5	no	41.241	41.287	EPSD	TCGA;ICGC;COSMIC	39.062	Up-regulation
Other_Aur_AURKA_ST	P04637	TP53	O14965	AURKA	S183	E180K	180	Missense	distal	-3	no	41.241	42.780	EPSD	TCGA;ICGC;COSMIC;CCLE	39.062	Up-regulation
Other_Aur_AURKA_ST	P04637	TP53	O14965	AURKA	S183	C176S	176	Missense	distal	-7	no	41.241	41.874	EPSD	TCGA;ICGC;COSMIC;GDSC;CCLE	39.062	Up-regulation
Other_Aur_AURKA_ST	P04637	TP53	O14965	AURKA	S183	H179N	179	Missense	distal	-4	no	41.241	47.028	EPSD	TCGA;ICGC;COSMIC	39.062	Up-regulation
Other_Aur_AURKA_ST	P04637	TP53	O14965	AURKA	S183	H179P	179	Missense	distal	-4	no	41.241	44.560	EPSD	TCGA;ICGC;COSMIC	39.062	Up-regulation
Other_Aur_AURKA_ST	P04637	TP53	O14965	AURKA	S183	H179L	179	Missense	distal	-4	no	41.241	45.711	EPSD	TCGA;ICGC;COSMIC	39.062	Up-regulation
Other_Aur_AURKA_ST	P04637	TP53	O14965	AURKA	S183	H179D	179	Missense	distal	-4	no	41.241	42.971	EPSD	TCGA;ICGC;COSMIC;GDSC;CCLE	39.062	Up-regulation
Other_Aur_AURKA_ST	P04637	TP53	O14965	AURKA	S183	P190R	190	Missense	distal	7	no	41.241	41.332	EPSD	TCGA;ICGC;COSMIC	39.062	Up-regulation
Other_Aur_AURKA_ST	P04637	TP53	O14965	AURKA	S183	P177R	177	Missense	distal	-6	no	41.241	42.820	EPSD	TCGA;ICGC;COSMIC	39.062	Up-regulation
Other_Aur_AURKA_ST	P04637	TP53	O14965	AURKA	S183	P177H	177	Missense	distal	-6	no	41.241	40.651	EPSD	TCGA;ICGC;COSMIC	39.062	Down-regulation
Other_Aur_AURKA_ST	P04637	TP53	O14965	AURKA	S183	C176W	176	Missense	distal	-7	no	41.241	39.148	EPSD	TCGA;ICGC;COSMIC;GDSC;CCLE	39.062	Down-regulation
Other_Aur_AURKA_ST	P04637	TP53	O14965	AURKA	S183	H179Q	179	Missense	distal	-4	no	41.241	45.829	EPSD	TCGA;ICGC;COSMIC;GDSC;CCLE	39.062	Up-regulation
Other_Aur_AURKA_ST	P04637	TP53	O14965	AURKA	S183	P177T	177	Missense	distal	-6	no	41.241	41.786	EPSD	TCGA;ICGC;COSMIC;GDSC;CCLE	39.062	Up-regulation
Other_Aur_AURKA_ST	P04637	TP53	O14965	AURKA	S183	R181P	181	Missense	proximal	-2	no	41.241	26.182	EPSD	TCGA;ICGC;COSMIC;CCLE	39.062	Loss
Other_Aur_AURKA_ST	P04637	TP53	O14965	AURKA	S183	C176R	176	Missense	distal	-7	no	41.241	42.448	EPSD	TCGA;ICGC;COSMIC	39.062	Up-regulation
Other_Aur_AURKA_ST	P04637	TP53	O14965	AURKA	S183	R181C	181	Missense	proximal	-2	no	41.241	25.944	EPSD	TCGA;ICGC;COSMIC;GDSC;CCLE	39.062	Loss
Other_Aur_AURKA_ST	P04637	TP53	O14965	AURKA	S183	P177L	177	Missense	distal	-6	no	41.241	40.260	EPSD	TCGA;ICGC;COSMIC;GDSC;CCLE	39.062	Down-regulation
Other_Aur_AURKA_ST	P04637	TP53	O14965	AURKA	S215	Y220C	220	Missense	distal	5	no	49.444	50.388	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC;GDSC;CCLE	39.062	Up-regulation
Other_Aur_AURKA_ST	P04637	TP53	O14965	AURKA	S215	R213Q	213	Missense	proximal	-2	no	49.444	38.805	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC;GDSC;CCLE	39.062	Loss
Other_Aur_AURKA_ST	P04637	TP53	O14965	AURKA	S215	D208N	208	Missense	distal	-7	no	49.444	49.052	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	39.062	Down-regulation
Other_Aur_AURKA_ST	P04637	TP53	O14965	AURKA	S215	H214R	214	Missense	proximal	-1	no	49.444	49.854	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC;GDSC;CCLE	39.062	Up-regulation
Other_Aur_AURKA_ST	P04637	TP53	O14965	AURKA	S215	V218E	218	Missense	distal	3	no	49.444	50.731	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	39.062	Up-regulation
Other_Aur_AURKA_ST	P04637	TP53	O14965	AURKA	S215	Y220H	220	Missense	distal	5	no	49.444	48.747	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	39.062	Down-regulation
Other_Aur_AURKA_ST	P04637	TP53	O14965	AURKA	S215	S215I	215	Missense	central	0	yes	49.444	0.000	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC;GDSC;CCLE	39.062	Loss
Other_Aur_AURKA_ST	P04637	TP53	O14965	AURKA	S215	V216M	216	Missense	proximal	1	no	49.444	49.443	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC;GDSC;CCLE	39.062	Down-regulation
Other_Aur_AURKA_ST	P04637	TP53	O14965	AURKA	S215	Y220S	220	Missense	distal	5	no	49.444	49.391	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	39.062	Down-regulation
Other_Aur_AURKA_ST	P04637	TP53	O14965	AURKA	S215	S215N	215	Missense	central	0	yes	49.444	0.000	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC;GDSC;CCLE	39.062	Loss
Other_Aur_AURKA_ST	P04637	TP53	O14965	AURKA	S215	T211I	211	Missense	distal	-4	no	49.444	41.737	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC;CCLE	39.062	Down-regulation
Other_Aur_AURKA_ST	P04637	TP53	O14965	AURKA	S215	V216G	216	Missense	proximal	1	no	49.444	47.104	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	39.062	Down-regulation
Other_Aur_AURKA_ST	P04637	TP53	O14965	AURKA	S215	R213L	213	Missense	proximal	-2	no	49.444	39.723	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC;GDSC;CCLE	39.062	Down-regulation
Other_Aur_AURKA_ST	P04637	TP53	O14965	AURKA	S215	Y220D	220	Missense	distal	5	no	49.444	50.325	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC;GDSC;CCLE	39.062	Up-regulation
Other_Aur_AURKA_ST	P04637	TP53	O14965	AURKA	S215	V216E	216	Missense	proximal	1	no	49.444	46.564	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	39.062	Down-regulation
Other_Aur_AURKA_ST	P04637	TP53	O14965	AURKA	S215	R209K	209	Missense	distal	-6	no	49.444	46.460	EPSD;PhosphoSitePlus	TCGA;COSMIC	39.062	Down-regulation
Other_Aur_AURKA_ST	P04637	TP53	O14965	AURKA	S215	V218G	218	Missense	distal	3	no	49.444	50.614	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	39.062	Up-regulation
Other_Aur_AURKA_ST	P04637	TP53	O14965	AURKA	S215	R213P	213	Missense	proximal	-2	no	49.444	34.385	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	39.062	Loss
Other_Aur_AURKA_ST	P04637	TP53	O14965	AURKA	S215	H214L	214	Missense	proximal	-1	no	49.444	48.295	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	39.062	Down-regulation
Other_Aur_AURKA_ST	P04637	TP53	O14965	AURKA	S215	V216L	216	Missense	proximal	1	no	49.444	50.353	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC;GDSC;CCLE	39.062	Up-regulation
Other_Aur_AURKA_ST	P04637	TP53	O14965	AURKA	S215	D208G	208	Missense	distal	-7	no	49.444	48.403	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	39.062	Down-regulation
Other_Aur_AURKA_ST	P04637	TP53	O14965	AURKA	S215	S215G	215	Missense	central	0	yes	49.444	0.000	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC;GDSC;CCLE	39.062	Loss
Other_Aur_AURKA_ST	P04637	TP53	O14965	AURKA	S215	R209S	209	Missense	distal	-6	no	49.444	48.414	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	39.062	Down-regulation
Other_Aur_AURKA_ST	P04637	TP53	O14965	AURKA	S215	R213G	213	Missense	proximal	-2	no	49.444	39.300	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	39.062	Down-regulation
Other_Aur_AURKA_ST	P04637	TP53	O14965	AURKA	S215	S215R	215	Missense	central	0	yes	49.444	0.000	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC;GDSC;CCLE	39.062	Loss
Other_Aur_AURKA_ST	P04637	TP53	O14965	AURKA	S215	R209I	209	Missense	distal	-6	no	49.444	41.013	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	39.062	Down-regulation
Other_Aur_AURKA_ST	P04637	TP53	O14965	AURKA	S215	T211A	211	Missense	distal	-4	no	49.444	44.486	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC;CCLE	39.062	Down-regulation
Other_Aur_AURKA_ST	P04637	TP53	O14965	AURKA	S269	R273C	273	Missense	distal	4	no	39.770	39.744	EPSD	TCGA;ICGC;COSMIC;GDSC;CCLE	39.062	Down-regulation
Other_Aur_AURKA_ST	P04637	TP53	O14965	AURKA	S269	C275S	275	Missense	distal	6	no	39.770	39.959	EPSD	TCGA;ICGC;COSMIC	39.062	Up-regulation
Other_Aur_AURKA_ST	P04637	TP53	O14965	AURKA	S269	R273L	273	Missense	distal	4	no	39.770	40.395	EPSD	TCGA;ICGC;COSMIC;GDSC;CCLE	39.062	Up-regulation
Other_Aur_AURKA_ST	P04637	TP53	O14965	AURKA	S269	E271K	271	Missense	proximal	2	no	39.770	36.705	EPSD	TCGA;ICGC;COSMIC;GDSC;CCLE	39.062	Loss
Other_Aur_AURKA_ST	P04637	TP53	O14965	AURKA	S269	C275Y	275	Missense	distal	6	no	39.770	39.889	EPSD	TCGA;ICGC;COSMIC;GDSC;CCLE	39.062	Up-regulation
Other_Aur_AURKA_ST	P04637	TP53	O14965	AURKA	S269	R273S	273	Missense	distal	4	no	39.770	40.301	EPSD	TCGA;ICGC;COSMIC	39.062	Up-regulation
Other_Aur_AURKA_ST	P04637	TP53	O14965	AURKA	S269	E271Q	271	Missense	proximal	2	no	39.770	40.109	EPSD	TCGA;ICGC;COSMIC	39.062	Up-regulation
Other_Aur_AURKA_ST	P04637	TP53	O14965	AURKA	S269	L265P	265	Missense	distal	-4	no	39.770	38.618	EPSD	TCGA;ICGC;COSMIC;GDSC;CCLE	39.062	Loss
Other_Aur_AURKA_ST	P04637	TP53	O14965	AURKA	S269	V272M	272	Missense	distal	3	no	39.770	41.224	EPSD	TCGA;ICGC;COSMIC;GDSC;CCLE	39.062	Up-regulation
Other_Aur_AURKA_ST	P04637	TP53	O14965	AURKA	S269	G266E	266	Missense	distal	-3	no	39.770	35.599	EPSD	TCGA;ICGC;COSMIC;GDSC;CCLE	39.062	Loss
Other_Aur_AURKA_ST	P04637	TP53	O14965	AURKA	S269	R273P	273	Missense	distal	4	no	39.770	40.248	EPSD	TCGA;ICGC;COSMIC	39.062	Up-regulation
Other_Aur_AURKA_ST	P04637	TP53	O14965	AURKA	S269	F270I	270	Missense	proximal	1	no	39.770	35.466	EPSD	TCGA;ICGC;COSMIC	39.062	Loss
Other_Aur_AURKA_ST	P04637	TP53	O14965	AURKA	S269	R273H	273	Missense	distal	4	no	39.770	40.440	EPSD	TCGA;ICGC;COSMIC;GDSC;CCLE	39.062	Up-regulation
Other_Aur_AURKA_ST	P04637	TP53	O14965	AURKA	S269	A276P	276	Missense	distal	7	no	39.770	39.714	EPSD	TCGA;ICGC;COSMIC	39.062	Down-regulation
Other_Aur_AURKA_ST	P04637	TP53	O14965	AURKA	S269	V272L	272	Missense	distal	3	no	39.770	40.231	EPSD	TCGA;ICGC;COSMIC;GDSC;CCLE	39.062	Up-regulation
Other_Aur_AURKA_ST	P04637	TP53	O14965	AURKA	S269	V274D	274	Missense	distal	5	no	39.770	41.621	EPSD	TCGA;ICGC;COSMIC;CCLE	39.062	Up-regulation
Other_Aur_AURKA_ST	P04637	TP53	O14965	AURKA	S269	G266V	266	Missense	distal	-3	no	39.770	39.801	EPSD	TCGA;ICGC;COSMIC;GDSC;CCLE	39.062	Up-regulation
Other_Aur_AURKA_ST	P04637	TP53	O14965	AURKA	S269	R267L	267	Missense	proximal	-2	no	39.770	30.049	EPSD	TCGA;ICGC;COSMIC;GDSC;CCLE	39.062	Loss
Other_Aur_AURKA_ST	P04637	TP53	O14965	AURKA	S269	R267W	267	Missense	proximal	-2	no	39.770	-146.938	EPSD	TCGA;ICGC;COSMIC;GDSC;CCLE	39.062	Loss
Other_Aur_AURKA_ST	P04637	TP53	O14965	AURKA	S269	R267Q	267	Missense	proximal	-2	no	39.770	29.131	EPSD	TCGA;ICGC;COSMIC;CCLE	39.062	Loss
Other_Aur_AURKA_ST	P04637	TP53	O14965	AURKA	S269	C275F	275	Missense	distal	6	no	39.770	40.104	EPSD	TCGA;ICGC;COSMIC;GDSC;CCLE	39.062	Up-regulation
Other_Aur_AURKA_ST	P04637	TP53	O14965	AURKA	S269	V274G	274	Missense	distal	5	no	39.770	40.788	EPSD	TCGA;ICGC;COSMIC;CCLE	39.062	Up-regulation
Other_Aur_AURKA_ST	P04637	TP53	O14965	AURKA	S269	V274L	274	Missense	distal	5	no	39.770	39.441	EPSD	TCGA;ICGC;COSMIC	39.062	Down-regulation
Other_Aur_AURKA_ST	P04637	TP53	O14965	AURKA	S269	G266R	266	Missense	distal	-3	no	39.770	44.963	EPSD	TCGA;ICGC;COSMIC;GDSC;CCLE	39.062	Up-regulation
Other_Aur_AURKA_ST	P04637	TP53	O14965	AURKA	S269	R267P	267	Missense	proximal	-2	no	39.770	24.711	EPSD	TCGA;ICGC;COSMIC;GDSC;CCLE	39.062	Loss
Other_Aur_AURKA_ST	P04637	TP53	O14965	AURKA	S269	A276D	276	Missense	distal	7	no	39.770	39.895	EPSD	TCGA;ICGC;COSMIC	39.062	Up-regulation
Other_Aur_AURKA_ST	P04637	TP53	O14965	AURKA	S269	L265R	265	Missense	distal	-4	no	39.770	39.734	EPSD	TCGA;ICGC;COSMIC	39.062	Down-regulation
Other_Aur_AURKA_ST	P04637	TP53	O14965	AURKA	S269	R267G	267	Missense	proximal	-2	no	39.770	29.626	EPSD	TCGA;ICGC;COSMIC	39.062	Loss
Other_Aur_AURKA_ST	P04637	TP53	O14965	AURKA	S269	F270C	270	Missense	proximal	1	no	39.770	31.376	EPSD	TCGA;ICGC;COSMIC	39.062	Loss
Other_Aur_AURKA_ST	P04637	TP53	O14965	AURKA	S269	E271V	271	Missense	proximal	2	no	39.770	38.863	EPSD	TCGA;ICGC;COSMIC	39.062	Loss
Other_Aur_AURKA_ST	P04637	TP53	O14965	AURKA	S269	G262V	262	Missense	distal	-7	no	39.770	41.100	EPSD	TCGA;ICGC;COSMIC;GDSC;CCLE	39.062	Up-regulation
Other_Aur_AURKA_ST	P04637	TP53	O14965	AURKA	S269	V274F	274	Missense	distal	5	no	39.770	41.398	EPSD	TCGA;ICGC;COSMIC;GDSC;CCLE	39.062	Up-regulation
Other_Aur_AURKA_ST	P04637	TP53	O14965	AURKA	S269	F270S	270	Missense	proximal	1	no	39.770	33.290	EPSD	TCGA;ICGC;COSMIC	39.062	Loss
Other_Aur_AURKA_ST	P04637	TP53	O14965	AURKA	S269	C275R	275	Missense	distal	6	no	39.770	39.940	EPSD	TCGA;ICGC;COSMIC	39.062	Up-regulation
Other_Aur_AURKA_ST	P04637	TP53	O14965	AURKA	S269	C275G	275	Missense	distal	6	no	39.770	39.957	EPSD	TCGA;ICGC;COSMIC;GDSC;CCLE	39.062	Up-regulation
Other_Aur_AURKA_ST	P04637	TP53	O14965	AURKA	S269	A276G	276	Missense	distal	7	no	39.770	39.943	EPSD	TCGA;ICGC;COSMIC	39.062	Up-regulation
Other_Aur_AURKA_ST	P04637	TP53	O14965	AURKA	S269	V272G	272	Missense	distal	3	no	39.770	40.940	EPSD	TCGA;ICGC;COSMIC	39.062	Up-regulation
Other_Aur_AURKA_ST	P04637	TP53	O14965	AURKA	S269	R273G	273	Missense	distal	4	no	39.770	40.579	EPSD	TCGA;ICGC;COSMIC	39.062	Up-regulation
Other_Aur_AURKA_ST	P04637	TP53	O14965	AURKA	S269	F270V	270	Missense	proximal	1	no	39.770	38.030	EPSD	TCGA;ICGC;COSMIC	39.062	Loss
Other_Aur_AURKA_ST	P04637	TP53	O14965	AURKA	S269	C275W	275	Missense	distal	6	no	39.770	40.150	EPSD	TCGA;ICGC;COSMIC	39.062	Up-regulation
Other_Aur_AURKA_ST	P04637	TP53	O14965	AURKA	S269	V272A	272	Missense	distal	3	no	39.770	39.892	EPSD	TCGA;ICGC;COSMIC	39.062	Up-regulation
Other_Aur_AURKA_ST	P04637	TP53	O14965	AURKA	S269	F270L	270	Missense	proximal	1	no	39.770	38.939	EPSD	TCGA;ICGC;COSMIC	39.062	Loss
Other_Aur_AURKA_ST	P04637	TP53	O14965	AURKA	S313	K319N	319	Missense	distal	6	no	41.824	41.793	EPSD	TCGA;ICGC;COSMIC	39.062	Down-regulation
Other_Aur_AURKA_ST	P04637	TP53	O14965	AURKA	S313	A307V	307	Missense	distal	-6	no	41.824	40.988	EPSD	TCGA;ICGC;COSMIC;GDSC	39.062	Down-regulation
Other_Aur_AURKA_ST	P04637	TP53	O14965	AURKA	S313	K320E	320	Missense	distal	7	no	41.824	41.934	EPSD	TCGA;ICGC;COSMIC	39.062	Up-regulation
Other_Aur_AURKA_ST	P04637	TP53	O14965	AURKA	S313	S315C	315	Missense	proximal	2	no	41.824	43.772	EPSD	TCGA;ICGC;COSMIC	39.062	Up-regulation
Other_Aur_AURKA_ST	P04637	TP53	O14965	AURKA	S315	K319N	319	Missense	distal	4	no	43.992	42.674	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	39.062	Down-regulation
Other_Aur_AURKA_ST	P04637	TP53	O14965	AURKA	S315	K320E	320	Missense	distal	5	no	43.992	43.465	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	39.062	Down-regulation
Other_Aur_AURKA_ST	P04637	TP53	O14965	AURKA	S315	S315C	315	Missense	central	0	yes	43.992	0.000	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	39.062	Loss
Other_Aur_AURKA_ST	Q13526	PIN1	O14965	AURKA	S32	R36P	36	Missense	distal	4	no	38.688	39.166	EPSD	TCGA;ICGC;COSMIC	39.062	Gain
Other_Aur_AURKA_ST	Q13526	PIN1	O14965	AURKA	S65	S71L	71	Missense	distal	6	no	45.733	45.669	EPSD	TCGA;ICGC;COSMIC	39.062	Down-regulation
Other_Aur_AURKA_ST	Q13526	PIN1	O14965	AURKA	S71	S71L	71	Missense	central	0	yes	43.245	0.000	EPSD	TCGA;ICGC;COSMIC	39.062	Loss
Other_Aur_AURKA_ST	Q13526	PIN1	O14965	AURKA	S111	S105F	105	Missense	distal	-6	no	40.034	34.376	EPSD	TCGA;ICGC;COSMIC	39.062	Loss
Other_Aur_AURKA_ST	Q13526	PIN1	O14965	AURKA	S111	D112N	112	Missense	proximal	1	no	40.034	34.460	EPSD	TCGA;ICGC;COSMIC	39.062	Loss
Other_Aur_AURKA_ST	Q13526	PIN1	O14965	AURKA	S111	E104K	104	Missense	distal	-7	no	40.034	40.678	EPSD	TCGA;ICGC;COSMIC	39.062	Up-regulation
Other_Aur_AURKA_ST	Q13526	PIN1	O14965	AURKA	S111	Q109R	109	Missense	proximal	-2	no	40.034	50.674	EPSD	TCGA;ICGC	39.062	Up-regulation
Other_Aur_AURKA_ST	Q13526	PIN1	O14965	AURKA	S115	D112N	112	Missense	distal	-3	no	35.907	40.562	EPSD	TCGA;ICGC;COSMIC	39.062	Gain
Other_Aur_AURKA_ST	Q9NWT8	AURKAIP1	O14965	AURKA	S70	E75D	75	Missense	distal	5	no	54.259	55.186	PhosphoSitePlus	TCGA;ICGC	39.062	Up-regulation
Other_Aur_AURKA_ST	Q9NWT8	AURKAIP1	O14965	AURKA	S70	S70C	70	Missense	central	0	yes	54.259	0.000	PhosphoSitePlus	TCGA;ICGC;COSMIC	39.062	Loss
Other_Aur_AURKA_ST	Q9NWT8	AURKAIP1	O14965	AURKA	S70	S70A	70	Missense	central	0	yes	54.259	0.000	PhosphoSitePlus	TCGA;ICGC;COSMIC	39.062	Loss
Other_Aur_AURKA_ST	Q8IX03	WWC1	O14965	AURKA	S270	S265C	265	Missense	distal	-5	no	40.751	40.879	EPSD	TCGA;ICGC;COSMIC	39.062	Up-regulation
Other_Aur_AURKA_ST	Q8IX03	WWC1	O14965	AURKA	S270	S269L	269	Missense	proximal	-1	no	40.751	39.182	EPSD	TCGA;ICGC;COSMIC	39.062	Down-regulation
Other_Aur_AURKA_ST	Q8IX03	WWC1	O14965	AURKA	S539	R537C	537	Missense	proximal	-2	no	48.897	33.600	PhosphoSitePlus	TCGA;ICGC;COSMIC	39.062	Loss
Other_Aur_AURKA_ST	Q8IX03	WWC1	O14965	AURKA	S539	L540F	540	Missense	proximal	1	no	48.897	49.727	PhosphoSitePlus	TCGA;ICGC;COSMIC	39.062	Up-regulation
Other_Aur_AURKA_ST	Q8IX03	WWC1	O14965	AURKA	S539	P536S	536	Missense	distal	-3	no	48.897	51.077	PhosphoSitePlus	TCGA;ICGC;COSMIC	39.062	Up-regulation
Other_Aur_AURKA_ST	Q8IX03	WWC1	O14965	AURKA	S539	S533F	533	Missense	distal	-6	no	48.897	43.238	PhosphoSitePlus	TCGA;ICGC;COSMIC	39.062	Down-regulation
Other_Aur_AURKA_ST	Q8IX03	WWC1	O14965	AURKA	S626	A621T	621	Missense	distal	-5	no	43.745	43.783	EPSD	TCGA;ICGC;COSMIC	39.062	Up-regulation
Other_Aur_AURKA_ST	Q8IX03	WWC1	O14965	AURKA	S626	E625K	625	Missense	proximal	-1	no	43.745	44.165	EPSD	TCGA;ICGC;COSMIC	39.062	Up-regulation
Other_Aur_AURKA_ST	Q8IX03	WWC1	O14965	AURKA	S626	V622I	622	Missense	distal	-4	no	43.745	37.322	EPSD	TCGA;ICGC;COSMIC	39.062	Loss
Other_Aur_AURKA_ST	Q8IX03	WWC1	O14965	AURKA	S834	K827N	827	Missense	distal	-7	no	40.057	39.759	EPSD	TCGA;ICGC;COSMIC	39.062	Down-regulation
Other_Aur_AURKA_ST	Q8IX03	WWC1	O14965	AURKA	S876	A875D	875	Missense	proximal	-1	no	42.717	43.927	EPSD	TCGA;ICGC	39.062	Up-regulation
Other_Aur_AURKA_ST	Q8IX03	WWC1	O14965	AURKA	T912	S914F	914	Missense	proximal	2	no	41.443	40.747	EPSD	TCGA;ICGC;COSMIC	39.062	Down-regulation
Other_Aur_AURKA_ST	Q8IX03	WWC1	O14965	AURKA	T912	P913L	913	Missense	proximal	1	no	41.443	46.093	EPSD	TCGA	39.062	Up-regulation
Other_Aur_AURKA_ST	Q8IX03	WWC1	O14965	AURKA	S922	R926C	926	Missense	distal	4	no	43.693	43.667	EPSD	TCGA;ICGC;COSMIC	39.062	Down-regulation
Other_Aur_AURKA_ST	Q8IX03	WWC1	O14965	AURKA	S922	R920L	920	Missense	proximal	-2	no	43.693	33.972	EPSD	TCGA;ICGC;COSMIC	39.062	Loss
Other_Aur_AURKA_ST	Q8IX03	WWC1	O14965	AURKA	S936	F930S	930	Missense	distal	-6	no	34.890	40.549	EPSD	TCGA;ICGC;COSMIC	39.062	Gain
Other_Aur_AURKA_ST	Q8IX03	WWC1	O14965	AURKA	S945	V939L	939	Missense	distal	-6	no	40.984	40.074	EPSD	TCGA;ICGC;COSMIC	39.062	Down-regulation
Other_Aur_AURKA_ST	Q8IX03	WWC1	O14965	AURKA	S945	R941W	941	Missense	distal	-4	no	40.984	33.081	EPSD	TCGA;ICGC;COSMIC	39.062	Loss
Other_Aur_AURKA_ST	Q8IX03	WWC1	O14965	AURKA	S962	R960Q	960	Missense	proximal	-2	no	39.988	29.348	EPSD	TCGA;ICGC;COSMIC	39.062	Loss
Other_Aur_AURKA_ST	Q8IX03	WWC1	O14965	AURKA	S962	S967N	967	Missense	distal	5	no	39.988	39.598	EPSD	TCGA;ICGC;COSMIC	39.062	Down-regulation
Other_Aur_AURKA_ST	Q8IX03	WWC1	O14965	AURKA	S962	V968I	968	Missense	distal	6	no	39.988	40.148	EPSD	TCGA;ICGC;COSMIC	39.062	Up-regulation
Other_Aur_AURKA_ST	Q8IX03	WWC1	O14965	AURKA	S978	R972Q	972	Missense	distal	-6	no	54.263	53.396	EPSD	TCGA;ICGC;COSMIC;GDSC	39.062	Down-regulation
Other_Aur_AURKA_ST	P10275	AR	O14965	AURKA	T282	E289K	289	Missense	distal	7	no	46.920	46.810	PhosphoSitePlus;EPSD	TCGA;ICGC;COSMIC	39.062	Down-regulation
Other_Aur_AURKA_ST	P10275	AR	O14965	AURKA	T282	R280C	280	Missense	proximal	-2	no	46.920	31.623	PhosphoSitePlus;EPSD	TCGA;ICGC;COSMIC	39.062	Loss
Other_Aur_AURKA_ST	P10275	AR	O14965	AURKA	S293	S293A	293	Missense	central	0	yes	46.780	0.000	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	39.062	Loss
Other_Aur_AURKA_ST	P10275	AR	O14965	AURKA	S293	E289K	289	Missense	distal	-4	no	46.780	46.971	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	39.062	Up-regulation
Other_Aur_AURKA_ST	P10275	AR	O14965	AURKA	S293	A299T	299	Missense	distal	6	no	46.780	46.676	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	39.062	Down-regulation
Other_Aur_AURKA_ST	P10275	AR	O14965	AURKA	S293	S293P	293	Missense	central	0	yes	46.780	0.000	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	39.062	Loss
Other_Aur_AURKA_ST	P10275	AR	O14965	AURKA	S293	D297N	297	Missense	distal	4	no	46.780	45.698	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	39.062	Down-regulation
Other_Aur_AURKA_ST	P10275	AR	O14965	AURKA	S298	S293A	293	Missense	distal	-5	no	39.510	39.480	EPSD	TCGA;ICGC;COSMIC	39.062	Down-regulation
Other_Aur_AURKA_ST	P10275	AR	O14965	AURKA	S298	A299T	299	Missense	proximal	1	no	39.510	37.838	EPSD	TCGA;ICGC;COSMIC	39.062	Loss
Other_Aur_AURKA_ST	P10275	AR	O14965	AURKA	S298	S293P	293	Missense	distal	-5	no	39.510	39.489	EPSD	TCGA;ICGC;COSMIC	39.062	Down-regulation
Other_Aur_AURKA_ST	P10275	AR	O14965	AURKA	S298	D297N	297	Missense	proximal	-1	no	39.510	36.348	EPSD	TCGA;ICGC;COSMIC	39.062	Loss
Other_Aur_AURKA_ST	P10275	AR	O14965	AURKA	S336	E340K	340	Missense	distal	4	no	39.251	39.235	EPSD	TCGA;ICGC;COSMIC	39.062	Down-regulation
Other_Aur_AURKA_ST	P10275	AR	O14965	AURKA	S792	M788I	788	Missense	distal	-4	no	40.139	35.252	EPSD	TCGA;ICGC;COSMIC	39.062	Loss
Other_Aur_AURKA_ST	P10275	AR	O14965	AURKA	S792	R787Q	787	Missense	distal	-5	no	40.139	40.128	EPSD	TCGA;ICGC;COSMIC	39.062	Down-regulation
Other_Aur_AURKA_ST	P10275	AR	O14965	AURKA	S792	L791I	791	Missense	proximal	-1	no	40.139	43.202	EPSD	TCGA;ICGC;COSMIC	39.062	Up-regulation
Other_Aur_AURKA_ST	P10275	AR	O14965	AURKA	S792	G796V	796	Missense	distal	4	no	40.139	39.601	EPSD	TCGA;ICGC;COSMIC	39.062	Down-regulation
Other_Aur_AURKA_ST	O15360	FANCA	O14965	AURKA	S165	Q168R	168	Missense	distal	3	no	47.693	47.305	PhosphoSitePlus	TCGA;ICGC	39.062	Down-regulation
Other_Aur_AURKA_ST	O15360	FANCA	O14965	AURKA	S1149	D1147V	1147	Missense	proximal	-2	no	51.498	49.120	EPSD	TCGA;ICGC;COSMIC	39.062	Down-regulation
Other_Aur_AURKA_ST	O15360	FANCA	O14965	AURKA	S1149	M1151I	1151	Missense	proximal	2	no	51.498	51.455	EPSD	TCGA;ICGC;COSMIC	39.062	Down-regulation
Other_Aur_AURKA_ST	O15360	FANCA	O14965	AURKA	S1374	V1369M	1369	Missense	distal	-5	no	40.044	40.067	EPSD	TCGA;ICGC;COSMIC	39.062	Up-regulation
Other_Aur_AURKA_ST	P53667	LIMK1	O14965	AURKA	S287	R289Q	289	Missense	proximal	2	no	38.991	40.991	EPSD	TCGA;COSMIC	39.062	Gain
Other_Aur_AURKA_ST	P53667	LIMK1	O14965	AURKA	S298	P303T	303	Missense	distal	5	no	41.520	42.512	EPSD	TCGA;COSMIC	39.062	Up-regulation
Other_Aur_AURKA_ST	P53667	LIMK1	O14965	AURKA	S337	R332H	332	Missense	distal	-5	no	39.376	39.320	EPSD	TCGA;COSMIC	39.062	Down-regulation
Other_Aur_AURKA_ST	P53667	LIMK1	O14965	AURKA	S337	G342E	342	Missense	distal	5	no	39.376	39.282	EPSD	TCGA;COSMIC	39.062	Down-regulation
Other_Aur_AURKA_ST	P53667	LIMK1	O14965	AURKA	S497	D502G	502	Missense	distal	5	no	41.100	40.267	EPSD	TCGA;COSMIC	39.062	Down-regulation
Other_Aur_AURKA_ST	P53667	LIMK1	O14965	AURKA	S497	L495M	495	Missense	proximal	-2	no	41.100	32.990	EPSD	TCGA;COSMIC	39.062	Loss
Other_Aur_AURKA_ST	P53667	LIMK1	O14965	AURKA	T508	D502G	502	Missense	distal	-6	no	40.996	41.050	PhosphoSitePlus;EPSD	TCGA;COSMIC	39.062	Up-regulation
Other_Aur_AURKA_ST	P53667	LIMK1	O14965	AURKA	T508	P513L	513	Missense	distal	5	no	40.996	40.413	PhosphoSitePlus;EPSD	TCGA;COSMIC	39.062	Down-regulation
Other_Aur_AURKA_ST	Q9BXS6	NUSAP1	O14965	AURKA	S149	A146T	146	Missense	distal	-3	no	46.924	45.200	EPSD	TCGA;ICGC;COSMIC	39.062	Down-regulation
Other_Aur_AURKA_ST	Q9BXS6	NUSAP1	O14965	AURKA	T166	L164I	164	Missense	proximal	-2	no	40.083	30.775	EPSD	TCGA;ICGC;COSMIC	39.062	Loss
Other_Aur_AURKA_ST	Q9BXS6	NUSAP1	O14965	AURKA	S240	R236T	236	Missense	distal	-4	no	47.179	49.977	PhosphoSitePlus	TCGA;ICGC;COSMIC	39.062	Up-regulation
Other_Aur_AURKA_ST	Q9BXS6	NUSAP1	O14965	AURKA	S240	P245L	245	Missense	distal	5	no	47.179	46.596	PhosphoSitePlus	TCGA;ICGC;COSMIC	39.062	Down-regulation
Other_Aur_AURKA_ST	Q9BXS6	NUSAP1	O14965	AURKA	S240	S243Y	243	Missense	distal	3	no	47.179	47.167	PhosphoSitePlus	TCGA;ICGC;COSMIC	39.062	Down-regulation
Other_Aur_AURKA_ST	Q9BXS6	NUSAP1	O14965	AURKA	S243	R236T	236	Missense	distal	-7	no	42.899	41.752	EPSD	TCGA;ICGC;COSMIC	39.062	Down-regulation
Other_Aur_AURKA_ST	Q9BXS6	NUSAP1	O14965	AURKA	S243	P245L	245	Missense	proximal	2	no	42.899	43.168	EPSD	TCGA;ICGC;COSMIC	39.062	Up-regulation
Other_Aur_AURKA_ST	Q9BXS6	NUSAP1	O14965	AURKA	S243	S243Y	243	Missense	central	0	yes	42.899	0.000	EPSD	TCGA;ICGC;COSMIC	39.062	Loss
Other_Aur_AURKA_ST	Q9BXS6	NUSAP1	O14965	AURKA	S251	P245L	245	Missense	distal	-6	no	43.033	42.052	EPSD	TCGA;ICGC;COSMIC	39.062	Down-regulation
Other_Aur_AURKA_ST	Q9BXS6	NUSAP1	O14965	AURKA	S269	S276C	276	Missense	distal	7	no	42.009	42.032	EPSD	TCGA;ICGC;COSMIC	39.062	Up-regulation
Other_Aur_AURKA_ST	Q9BXS6	NUSAP1	O14965	AURKA	S269	R272C	272	Missense	distal	3	no	42.009	40.737	EPSD	TCGA;ICGC;COSMIC	39.062	Down-regulation
Other_Aur_AURKA_ST	Q9BXS6	NUSAP1	O14965	AURKA	S269	T263A	263	Missense	distal	-6	no	42.009	42.230	EPSD	TCGA;ICGC;COSMIC	39.062	Up-regulation
Other_Aur_AURKA_ST	Q9BXS6	NUSAP1	O14965	AURKA	S269	S273T	273	Missense	distal	4	no	42.009	40.994	EPSD	TCGA;ICGC;COSMIC	39.062	Down-regulation
Other_Aur_AURKA_ST	Q9BXS6	NUSAP1	O14965	AURKA	S296	R295C	295	Missense	proximal	-1	no	39.557	39.341	EPSD	TCGA;ICGC	39.062	Down-regulation
Other_Aur_AURKA_ST	Q9BXS6	NUSAP1	O14965	AURKA	T309	V310M	310	Missense	proximal	1	no	43.538	43.537	EPSD	TCGA;ICGC;COSMIC	39.062	Down-regulation
Other_Aur_AURKA_ST	Q9BXS6	NUSAP1	O14965	AURKA	S363	D359H	359	Missense	distal	-4	no	40.882	39.151	EPSD	TCGA;ICGC;COSMIC	39.062	Down-regulation
Other_Aur_AURKA_ST	P49450	CENPA	O14965	AURKA	S32	A35T	35	Missense	distal	3	no	45.951	44.819	EPSD	TCGA;ICGC;COSMIC	39.062	Down-regulation
Other_Aur_AURKA_ST	Q9NS23	RASSF1	O14965	AURKA	S179	V175M	175	Missense	distal	-4	no	41.817	40.281	EPSD	TCGA;COSMIC	39.062	Down-regulation
Other_Aur_AURKA_ST	Q9NS23	RASSF1	O14965	AURKA	S188	R194W	194	Missense	distal	6	no	40.145	40.354	EPSD	TCGA	39.062	Up-regulation
Other_Aur_AURKA_ST	Q9NS23	RASSF1	O14965	AURKA	S201	R205C	205	Missense	distal	4	no	42.544	42.518	EPSD	TCGA;COSMIC	39.062	Down-regulation
Other_Aur_AURKA_ST	Q9NS23	RASSF1	O14965	AURKA	S201	V202A	202	Missense	proximal	1	no	42.544	42.724	EPSD	TCGA;COSMIC	39.062	Up-regulation
Other_Aur_AURKA_ST	Q9NS23	RASSF1	O14965	AURKA	S201	R194W	194	Missense	distal	-7	no	42.544	39.245	EPSD	TCGA	39.062	Down-regulation
Other_Aur_AURKA_ST	Q9NS23	RASSF1	O14965	AURKA	T206	R205C	205	Missense	proximal	-1	no	48.585	48.369	EPSD	TCGA;COSMIC	39.062	Down-regulation
Other_Aur_AURKA_ST	Q9NS23	RASSF1	O14965	AURKA	T206	V202A	202	Missense	distal	-4	no	48.585	44.910	EPSD	TCGA;COSMIC	39.062	Down-regulation
Other_Aur_AURKA_ST	Q9NS23	RASSF1	O14965	AURKA	S207	R205C	205	Missense	proximal	-2	no	58.455	43.158	EPSD	TCGA;COSMIC	39.062	Down-regulation
Other_Aur_AURKA_ST	Q9NS23	RASSF1	O14965	AURKA	S207	V202A	202	Missense	distal	-5	no	58.455	58.430	EPSD	TCGA;COSMIC	39.062	Down-regulation
Other_Aur_AURKA_ST	P49736	MCM2	O14965	AURKA	T158	R152H	152	Missense	distal	-6	no	43.684	41.515	EPSD	TCGA;ICGC;COSMIC	39.062	Down-regulation
Other_Aur_AURKA_ST	P49736	MCM2	O14965	AURKA	T158	E165K	165	Missense	distal	7	no	43.684	43.573	EPSD	TCGA;ICGC;COSMIC	39.062	Down-regulation
Other_Aur_AURKA_ST	P49736	MCM2	O14965	AURKA	S220	R218H	218	Missense	proximal	-2	no	55.596	48.357	PhosphoSitePlus	TCGA;ICGC;COSMIC;GDSC	39.062	Down-regulation
Other_Aur_AURKA_ST	P49736	MCM2	O14965	AURKA	S220	E225D	225	Missense	distal	5	no	55.596	56.523	PhosphoSitePlus	TCGA;ICGC;COSMIC	39.062	Up-regulation
Other_Aur_AURKA_ST	P49736	MCM2	O14965	AURKA	S220	N213D	213	Missense	distal	-7	no	55.596	55.988	PhosphoSitePlus	TCGA;ICGC	39.062	Up-regulation
Other_Aur_AURKA_ST	P49736	MCM2	O14965	AURKA	S229	E225D	225	Missense	distal	-4	no	45.165	40.943	EPSD	TCGA;ICGC;COSMIC	39.062	Down-regulation
Other_Aur_AURKA_ST	P49736	MCM2	O14965	AURKA	S541	E537K	537	Missense	distal	-4	no	43.974	44.165	EPSD	TCGA;ICGC;COSMIC	39.062	Up-regulation
Other_Aur_AURKA_ST	P49736	MCM2	O14965	AURKA	S541	V539L	539	Missense	proximal	-2	no	43.974	45.293	EPSD	TCGA;ICGC;COSMIC	39.062	Up-regulation
Other_Aur_AURKA_ST	P49736	MCM2	O14965	AURKA	S754	R751K	751	Missense	distal	-3	no	43.194	35.368	EPSD	TCGA;ICGC;COSMIC	39.062	Loss
Other_Aur_AURKA_ST	O75496	GMNN	O14965	AURKA	S34	S34F	34	Missense	central	0	yes	41.875	0.000	EPSD	TCGA;ICGC;COSMIC	39.062	Loss
Other_Aur_AURKA_ST	O75496	GMNN	O14965	AURKA	S45	A46T	46	Missense	proximal	1	no	40.010	38.338	EPSD	TCGA;ICGC	39.062	Loss
Other_Aur_AURKA_ST	O75496	GMNN	O14965	AURKA	S45	A46S	46	Missense	proximal	1	no	40.010	35.090	EPSD	TCGA;ICGC;COSMIC	39.062	Loss
Other_Aur_AURKA_ST	P11233	RALA	O14965	AURKA	S129	L123I	123	Missense	distal	-6	no	40.238	34.367	EPSD	TCGA;ICGC	39.062	Loss
Other_Aur_AURKA_ST	P11233	RALA	O14965	AURKA	S129	L131F	131	Missense	proximal	2	no	40.238	40.521	EPSD	TCGA;ICGC;COSMIC	39.062	Up-regulation
Other_Aur_AURKA_ST	P11233	RALA	O14965	AURKA	S129	K134E	134	Missense	distal	5	no	40.238	39.711	EPSD	TCGA;ICGC;COSMIC	39.062	Down-regulation
Other_Aur_AURKA_ST	P11233	RALA	O14965	AURKA	S129	L131S	131	Missense	proximal	2	no	40.238	41.217	EPSD	TCGA	39.062	Up-regulation
Other_Aur_AURKA_ST	P11233	RALA	O14965	AURKA	S129	K128I	128	Missense	proximal	-1	no	40.238	42.091	EPSD	TCGA;ICGC;COSMIC	39.062	Up-regulation
Other_Aur_AURKA_ST	P11233	RALA	O14965	AURKA	S138	E141K	141	Missense	distal	3	no	47.654	46.258	EPSD	TCGA;ICGC;COSMIC	39.062	Down-regulation
Other_Aur_AURKA_ST	P11233	RALA	O14965	AURKA	S138	L131F	131	Missense	distal	-7	no	47.654	47.298	EPSD	TCGA;ICGC;COSMIC	39.062	Down-regulation
Other_Aur_AURKA_ST	P11233	RALA	O14965	AURKA	S138	K134E	134	Missense	distal	-4	no	47.654	47.463	EPSD	TCGA;ICGC;COSMIC	39.062	Down-regulation
Other_Aur_AURKA_ST	P11233	RALA	O14965	AURKA	S138	L131S	131	Missense	distal	-7	no	47.654	47.467	EPSD	TCGA	39.062	Down-regulation
Other_Aur_AURKA_ST	Q9Y6A5	TACC3	O14965	AURKA	S34	P27S	27	Missense	distal	-7	no	51.131	49.271	EPSD	TCGA;ICGC;CCLE	39.062	Down-regulation
Other_Aur_AURKA_ST	Q9Y6A5	TACC3	O14965	AURKA	S34	L36I	36	Missense	proximal	2	no	51.131	51.324	EPSD	TCGA;ICGC;COSMIC	39.062	Up-regulation
Other_Aur_AURKA_ST	Q9Y6A5	TACC3	O14965	AURKA	S39	V44L	44	Missense	distal	5	no	40.106	39.777	EPSD	TCGA;ICGC;COSMIC	39.062	Down-regulation
Other_Aur_AURKA_ST	Q9Y6A5	TACC3	O14965	AURKA	S39	L36I	36	Missense	distal	-3	no	40.106	39.351	EPSD	TCGA;ICGC;COSMIC	39.062	Down-regulation
Other_Aur_AURKA_ST	Q9Y6A5	TACC3	O14965	AURKA	T87	D86N	86	Missense	proximal	-1	no	47.660	44.499	EPSD	TCGA;ICGC;COSMIC	39.062	Down-regulation
Other_Aur_AURKA_ST	Q9Y6A5	TACC3	O14965	AURKA	S402	S399Y	399	Missense	distal	-3	no	46.420	43.283	EPSD	TCGA;ICGC;COSMIC	39.062	Down-regulation
Other_Aur_AURKA_ST	Q9Y6A5	TACC3	O14965	AURKA	S402	D406N	406	Missense	distal	4	no	46.420	45.337	EPSD	TCGA;ICGC;COSMIC	39.062	Down-regulation
Other_Aur_AURKA_ST	Q9Y6A5	TACC3	O14965	AURKA	S402	R400W	400	Missense	proximal	-2	no	46.420	-140.288	EPSD	TCGA;ICGC;COSMIC	39.062	Loss
Other_Aur_AURKA_ST	Q9Y6A5	TACC3	O14965	AURKA	S558	L554F	554	Missense	distal	-4	no	53.776	50.492	PhosphoSitePlus	TCGA;ICGC;COSMIC;GDSC;CCLE	39.062	Down-regulation
Other_Aur_AURKA_ST	Q9Y6A5	TACC3	O14965	AURKA	S570	S570I	570	Missense	central	0	yes	48.144	0.000	EPSD	TCGA;ICGC;COSMIC;CCLE	39.062	Loss
Other_Aur_AURKA_ST	P25490	YY1	O14965	AURKA	S165	S159G	159	Missense	distal	-6	no	45.006	42.245	EPSD	TCGA;ICGC;COSMIC	39.062	Down-regulation
Other_Aur_AURKA_ST	P25490	YY1	O14965	AURKA	S252	S252L	252	Missense	central	0	yes	42.387	0.000	EPSD	TCGA;ICGC;COSMIC	39.062	Loss
Other_Aur_AURKA_ST	P25490	YY1	O14965	AURKA	S252	S247L	247	Missense	distal	-5	no	42.387	42.379	EPSD	TCGA;ICGC;COSMIC	39.062	Down-regulation
Other_Aur_AURKA_ST	P25490	YY1	O14965	AURKA	S252	E245D	245	Missense	distal	-7	no	42.387	43.125	EPSD	TCGA;ICGC;COSMIC	39.062	Up-regulation
Other_Aur_AURKA_ST	P25490	YY1	O14965	AURKA	S311	F307L	307	Missense	distal	-4	no	40.554	43.837	EPSD	TCGA;ICGC;COSMIC	39.062	Up-regulation
Other_Aur_AURKA_ST	P25490	YY1	O14965	AURKA	S311	H316R	316	Missense	distal	5	no	40.554	40.045	EPSD	TCGA;ICGC	39.062	Down-regulation
Other_Aur_AURKA_ST	P25490	YY1	O14965	AURKA	S365	R363H	363	Missense	proximal	-2	no	45.539	38.301	PhosphoSitePlus	TCGA;ICGC	39.062	Loss
Other_Aur_AURKA_ST	P25490	YY1	O14965	AURKA	S365	E358K	358	Missense	distal	-7	no	45.539	46.183	PhosphoSitePlus	TCGA;ICGC	39.062	Up-regulation
Other_Aur_AURKA_ST	P30305	CDC25B	O14965	AURKA	T86	R92Q	92	Missense	distal	6	no	39.121	39.077	EPSD	TCGA;COSMIC	39.062	Down-regulation
Other_Aur_AURKA_ST	P30305	CDC25B	O14965	AURKA	T86	S89Y	89	Missense	distal	3	no	39.121	39.108	EPSD	TCGA;COSMIC	39.062	Down-regulation
Other_Aur_AURKA_ST	P30305	CDC25B	O14965	AURKA	T86	R82H	82	Missense	distal	-4	no	39.121	34.686	EPSD	TCGA;ICGC	39.062	Loss
Other_Aur_AURKA_ST	P30305	CDC25B	O14965	AURKA	T86	R84H	84	Missense	proximal	-2	no	39.121	31.882	EPSD	TCGA;COSMIC	39.062	Loss
Other_Aur_AURKA_ST	P30305	CDC25B	O14965	AURKA	S89	R92Q	92	Missense	distal	3	no	42.061	42.449	EPSD	TCGA;COSMIC	39.062	Up-regulation
Other_Aur_AURKA_ST	P30305	CDC25B	O14965	AURKA	S89	S89Y	89	Missense	central	0	yes	42.061	0.000	EPSD	TCGA;COSMIC	39.062	Loss
Other_Aur_AURKA_ST	P30305	CDC25B	O14965	AURKA	S89	E96K	96	Missense	distal	7	no	42.061	41.950	EPSD	TCGA;COSMIC	39.062	Down-regulation
Other_Aur_AURKA_ST	P30305	CDC25B	O14965	AURKA	S89	R82H	82	Missense	distal	-7	no	42.061	40.585	EPSD	TCGA;ICGC	39.062	Down-regulation
Other_Aur_AURKA_ST	P30305	CDC25B	O14965	AURKA	S89	R84H	84	Missense	distal	-5	no	42.061	42.004	EPSD	TCGA;COSMIC	39.062	Down-regulation
Other_Aur_AURKA_ST	P30305	CDC25B	O14965	AURKA	S115	G110C	110	Missense	distal	-5	no	43.504	43.647	EPSD	TCGA;ICGC;COSMIC	39.062	Up-regulation
Other_Aur_AURKA_ST	P30305	CDC25B	O14965	AURKA	S115	G110D	110	Missense	distal	-5	no	43.504	43.537	EPSD	TCGA;COSMIC	39.062	Up-regulation
Other_Aur_AURKA_ST	P30305	CDC25B	O14965	AURKA	S115	S115F	115	Missense	central	0	yes	43.504	0.000	EPSD	TCGA;COSMIC	39.062	Loss
Other_Aur_AURKA_ST	P30305	CDC25B	O14965	AURKA	T344	P345L	345	Missense	proximal	1	no	38.050	42.700	EPSD	TCGA;COSMIC	39.062	Gain
Other_Aur_AURKA_ST	P30305	CDC25B	O14965	AURKA	S353	E358K	358	Missense	distal	5	no	50.158	50.685	PhosphoSitePlus	TCGA;ICGC;COSMIC	39.062	Up-regulation
Other_Aur_AURKA_ST	P30305	CDC25B	O14965	AURKA	S353	R352W	352	Missense	proximal	-1	no	50.158	53.833	PhosphoSitePlus	TCGA;ICGC;COSMIC	39.062	Up-regulation
Other_Aur_AURKA_ST	P30305	CDC25B	O14965	AURKA	S375	E380Q	380	Missense	distal	5	no	39.179	40.400	EPSD	TCGA;COSMIC	39.062	Up-regulation
Other_Aur_AURKA_ST	P30305	CDC25B	O14965	AURKA	S375	S373T	373	Missense	proximal	-2	no	39.179	33.124	EPSD	TCGA;ICGC;COSMIC	39.062	Loss
Other_Aur_AURKA_ST	P30305	CDC25B	O14965	AURKA	S375	R369H	369	Missense	distal	-6	no	39.179	37.009	EPSD	TCGA;COSMIC	39.062	Loss
Atypical_GTF2F1_GTF2F1_ST	P35269	GTF2F1	P35269	GTF2F1	S261	G268S	268	Missense	distal	7	no	1.938	1.941	EPSD	TCGA;COSMIC	1.654	Up-regulation
Atypical_GTF2F1_GTF2F1_ST	P35269	GTF2F1	P35269	GTF2F1	S355	S355N	355	Missense	central	0	yes	2.061	0.000	EPSD	TCGA;COSMIC	1.654	Loss
Atypical_GTF2F1_GTF2F1_ST	P35269	GTF2F1	P35269	GTF2F1	S355	E356G	356	Missense	proximal	1	no	2.061	3.025	EPSD	TCGA;COSMIC	1.654	Up-regulation
Atypical_GTF2F1_GTF2F1_ST	P35269	GTF2F1	P35269	GTF2F1	S355	A357T	357	Missense	proximal	2	no	2.061	2.164	EPSD	TCGA;COSMIC	1.654	Up-regulation
Atypical_GTF2F1_GTF2F1_ST	P35269	GTF2F1	P35269	GTF2F1	S355	D352Y	352	Missense	distal	-3	no	2.061	2.016	EPSD	TCGA	1.654	Down-regulation
Atypical_GTF2F1_GTF2F1_ST	P35269	GTF2F1	P35269	GTF2F1	S380	S381P	381	Missense	proximal	1	no	1.297	2.864	EPSD	TCGA;COSMIC	1.654	Gain
Atypical_GTF2F1_GTF2F1_ST	P35269	GTF2F1	P35269	GTF2F1	S385	P390S	390	Missense	distal	5	no	7.288	5.179	PhosphoSitePlus;EPSD	TCGA;COSMIC	1.654	Down-regulation
Atypical_GTF2F1_GTF2F1_ST	P35269	GTF2F1	P35269	GTF2F1	S385	A392T	392	Missense	distal	7	no	7.288	7.282	PhosphoSitePlus;EPSD	TCGA	1.654	Down-regulation
Atypical_GTF2F1_GTF2F1_ST	P35269	GTF2F1	P35269	GTF2F1	S385	S381P	381	Missense	distal	-4	no	7.288	7.205	PhosphoSitePlus;EPSD	TCGA;COSMIC	1.654	Down-regulation
Atypical_GTF2F1_GTF2F1_ST	P35269	GTF2F1	P35269	GTF2F1	T389	P390S	390	Missense	proximal	1	no	8.110	6.543	EPSD;PhosphoSitePlus	TCGA;COSMIC	1.654	Down-regulation
Atypical_GTF2F1_GTF2F1_ST	P35269	GTF2F1	P35269	GTF2F1	T389	A392T	392	Missense	distal	3	no	8.110	8.052	EPSD;PhosphoSitePlus	TCGA	1.654	Down-regulation
Atypical_GTF2F1_GTF2F1_ST	P35269	GTF2F1	P35269	GTF2F1	S436	S442L	442	Missense	distal	6	no	2.034	2.132	EPSD	TCGA;COSMIC	1.654	Up-regulation
Atypical_GTF2F1_GTF2F1_ST	P35269	GTF2F1	P35269	GTF2F1	S442	S442L	442	Missense	central	0	yes	2.096	0.000	EPSD	TCGA;COSMIC	1.654	Loss
Atypical_GTF2F1_GTF2F1_ST	P35269	GTF2F1	P35269	GTF2F1	T445	S442L	442	Missense	distal	-3	no	2.314	2.259	EPSD	TCGA;COSMIC	1.654	Down-regulation
Atypical_GTF2F1_GTF2F1_ST	P13631	RARG	P35269	GTF2F1	S36	S43I	43	Missense	distal	7	no	1.963	1.973	EPSD	TCGA;ICGC;COSMIC	1.654	Up-regulation
Atypical_GTF2F1_GTF2F1_ST	P13631	RARG	P35269	GTF2F1	S36	M41I	41	Missense	distal	5	no	1.963	1.979	EPSD	TCGA;ICGC;COSMIC	1.654	Up-regulation
Atypical_GTF2F1_GTF2F1_ST	P13631	RARG	P35269	GTF2F1	S36	G35R	35	Missense	proximal	-1	no	1.963	2.038	EPSD	TCGA;ICGC;COSMIC	1.654	Up-regulation
Atypical_GTF2F1_GTF2F1_ST	P13631	RARG	P35269	GTF2F1	S43	S43I	43	Missense	central	0	yes	3.549	0.000	EPSD	TCGA;ICGC;COSMIC	1.654	Loss
Atypical_GTF2F1_GTF2F1_ST	P13631	RARG	P35269	GTF2F1	S43	M41I	41	Missense	proximal	-2	no	3.549	3.568	EPSD	TCGA;ICGC;COSMIC	1.654	Up-regulation
Atypical_GTF2F1_GTF2F1_ST	P13631	RARG	P35269	GTF2F1	S43	P44L	44	Missense	proximal	1	no	3.549	1.739	EPSD	TCGA;ICGC;COSMIC	1.654	Down-regulation
Atypical_GTF2F1_GTF2F1_ST	P13631	RARG	P35269	GTF2F1	S76	P82L	82	Missense	distal	6	no	2.128	2.302	EPSD	TCGA;ICGC;COSMIC	1.654	Up-regulation
Atypical_GTF2F1_GTF2F1_ST	P13631	RARG	P35269	GTF2F1	S76	S77L	77	Missense	proximal	1	no	2.128	1.884	EPSD	TCGA;ICGC;COSMIC	1.654	Down-regulation
Atypical_GTF2F1_GTF2F1_ST	P13631	RARG	P35269	GTF2F1	S76	P82A	82	Missense	distal	6	no	2.128	2.259	EPSD	TCGA;COSMIC	1.654	Up-regulation
Atypical_GTF2F1_GTF2F1_ST	P13631	RARG	P35269	GTF2F1	S77	P82L	82	Missense	distal	5	no	8.594	5.913	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	1.654	Down-regulation
Atypical_GTF2F1_GTF2F1_ST	P13631	RARG	P35269	GTF2F1	S77	S77L	77	Missense	central	0	yes	8.594	0.000	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	1.654	Loss
Atypical_GTF2F1_GTF2F1_ST	P13631	RARG	P35269	GTF2F1	S77	P82A	82	Missense	distal	5	no	8.594	6.586	EPSD;PhosphoSitePlus	TCGA;COSMIC	1.654	Down-regulation
Atypical_GTF2F1_GTF2F1_ST	P13631	RARG	P35269	GTF2F1	S79	P82L	82	Missense	distal	3	no	7.873	7.456	PhosphoSitePlus;EPSD	TCGA;ICGC;COSMIC	1.654	Down-regulation
Atypical_GTF2F1_GTF2F1_ST	P13631	RARG	P35269	GTF2F1	S79	S77L	77	Missense	proximal	-2	no	7.873	7.441	PhosphoSitePlus;EPSD	TCGA;ICGC;COSMIC	1.654	Down-regulation
Atypical_GTF2F1_GTF2F1_ST	P13631	RARG	P35269	GTF2F1	S79	P82A	82	Missense	distal	3	no	7.873	7.546	PhosphoSitePlus;EPSD	TCGA;COSMIC	1.654	Down-regulation
AGC_NDR_LATS_LATS1_ST	Q9NQS7	INCENP	O95835	LATS1	S72	R69K	69	Missense	distal	-3	no	0.003	0.000	EPSD	TCGA	0.001	Loss
AGC_NDR_LATS_LATS1_ST	Q9NQS7	INCENP	O95835	LATS1	S91	R88H	88	Missense	distal	-3	no	0.003	0.001	EPSD	TCGA;ICGC	0.001	Down-regulation
AGC_NDR_LATS_LATS1_ST	Q9NQS7	INCENP	O95835	LATS1	S93	R88H	88	Missense	distal	-5	no	0.001	0.002	EPSD	TCGA;ICGC	0.001	Up-regulation
AGC_NDR_LATS_LATS1_ST	Q9NQS7	INCENP	O95835	LATS1	S103	R100S	100	Missense	distal	-3	no	0.002	-0.001	EPSD	TCGA;ICGC;COSMIC	0.001	Loss
AGC_NDR_LATS_LATS1_ST	Q9NQS7	INCENP	O95835	LATS1	S103	S103I	103	Missense	central	0	yes	0.002	0.000	EPSD	TCGA;ICGC;COSMIC	0.001	Loss
AGC_NDR_LATS_LATS1_ST	Q9NQS7	INCENP	O95835	LATS1	S197	R194H	194	Missense	distal	-3	no	0.003	0.001	EPSD	TCGA;ICGC;COSMIC	0.001	Down-regulation
AGC_NDR_LATS_LATS1_ST	Q9NQS7	INCENP	O95835	LATS1	T199	R194H	194	Missense	distal	-5	no	0.001	0.002	EPSD	TCGA;ICGC;COSMIC	0.001	Up-regulation
AGC_NDR_LATS_LATS1_ST	Q9NQS7	INCENP	O95835	LATS1	S255	S255P	255	Missense	central	0	yes	0.003	0.000	EPSD	TCGA;ICGC;COSMIC	0.001	Loss
AGC_NDR_LATS_LATS1_ST	Q9NQS7	INCENP	O95835	LATS1	S263	S263F	263	Missense	central	0	yes	0.001	0.000	EPSD	TCGA;ICGC;COSMIC	0.001	Loss
AGC_NDR_LATS_LATS1_ST	Q9NQS7	INCENP	O95835	LATS1	S300	R297C	297	Missense	distal	-3	no	0.003	0.000	EPSD	TCGA;ICGC;COSMIC	0.001	Loss
AGC_NDR_LATS_LATS1_ST	Q9NQS7	INCENP	O95835	LATS1	S302	R297C	297	Missense	distal	-5	no	0.001	0.000	EPSD	TCGA;ICGC;COSMIC	0.001	Loss
AGC_NDR_LATS_LATS1_ST	Q9NQS7	INCENP	O95835	LATS1	T478	T478I	478	Missense	central	0	yes	0.003	0.000	EPSD	TCGA;ICGC;COSMIC	0.001	Loss
AGC_NDR_LATS_LATS1_ST	Q9NQS7	INCENP	O95835	LATS1	T498	L492P	492	Missense	distal	-6	no	0.001	0.000	EPSD	TCGA	0.001	Loss
AGC_NDR_LATS_LATS1_ST	Q9NQS7	INCENP	O95835	LATS1	T498	P491A	491	Missense	distal	-7	no	0.001	0.000	EPSD	TCGA;ICGC;COSMIC	0.001	Loss
AGC_NDR_LATS_LATS1_ST	Q9NQS7	INCENP	O95835	LATS1	S518	R513S	513	Missense	distal	-5	no	0.001	0.000	EPSD	TCGA;ICGC	0.001	Loss
AGC_NDR_LATS_LATS1_ST	Q9NQS7	INCENP	O95835	LATS1	S518	R513C	513	Missense	distal	-5	no	0.001	0.000	EPSD	TCGA;ICGC	0.001	Loss
AGC_NDR_LATS_LATS1_ST	Q9NQS7	INCENP	O95835	LATS1	S852	R847Q	847	Missense	distal	-5	no	0.001	0.000	EPSD	TCGA;ICGC;COSMIC	0.001	Loss
AGC_NDR_LATS_LATS1_ST	Q9NQS7	INCENP	O95835	LATS1	S894	S894F	894	Missense	central	0	yes	0.005	0.000	PhosphoSitePlus	TCGA;ICGC;COSMIC	0.001	Loss
AGC_NDR_LATS_LATS1_ST	P46937	YAP1	O95835	LATS1	S61	S61W	61	Missense	central	0	yes	0.005	0.000	PhosphoSitePlus;EPSD	TCGA;ICGC;COSMIC	0.001	Loss
AGC_NDR_LATS_LATS1_ST	P46937	YAP1	O95835	LATS1	S109	R106Q	106	Missense	distal	-3	no	0.005	0.002	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC;CCLE	0.001	Down-regulation
AGC_NDR_LATS_LATS1_ST	P46937	YAP1	O95835	LATS1	S109	S109N	109	Missense	central	0	yes	0.005	0.000	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	0.001	Loss
AGC_NDR_LATS_LATS1_ST	P46937	YAP1	O95835	LATS1	S127	R124P	124	Missense	distal	-3	no	0.005	0.002	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	0.001	Down-regulation
AGC_NDR_LATS_LATS1_ST	P46937	YAP1	O95835	LATS1	S127	R124Q	124	Missense	distal	-3	no	0.005	0.002	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	0.001	Down-regulation
AGC_NDR_LATS_LATS1_ST	P46937	YAP1	O95835	LATS1	S131	P129S	129	Missense	proximal	-2	no	0.001	0.002	EPSD	TCGA;ICGC;COSMIC	0.001	Up-regulation
AGC_NDR_LATS_LATS1_ST	P46937	YAP1	O95835	LATS1	S163	Q158H	158	Missense	distal	-5	no	0.000	0.002	EPSD	TCGA;ICGC;COSMIC	0.001	Gain
AGC_NDR_LATS_LATS1_ST	O95835	LATS1	O95835	LATS1	S177	R174H	174	Missense	distal	-3	no	0.003	0.001	EPSD	TCGA;ICGC;COSMIC	0.001	Down-regulation
AGC_NDR_LATS_LATS1_ST	O95835	LATS1	O95835	LATS1	S197	P192S	192	Missense	distal	-5	no	0.001	0.000	EPSD	TCGA;ICGC;COSMIC	0.001	Loss
AGC_NDR_LATS_LATS1_ST	O95835	LATS1	O95835	LATS1	T255	P250S	250	Missense	distal	-5	no	0.003	0.002	EPSD	TCGA;ICGC;GDSC;CCLE	0.001	Down-regulation
AGC_NDR_LATS_LATS1_ST	O95835	LATS1	O95835	LATS1	S267	P264H	264	Missense	distal	-3	no	0.000	0.001	EPSD	TCGA;ICGC;COSMIC	0.001	Gain
AGC_NDR_LATS_LATS1_ST	O95835	LATS1	O95835	LATS1	S464	S464F	464	Missense	central	0	yes	0.003	0.000	EPSD	TCGA;ICGC;COSMIC	0.001	Loss
AGC_NDR_LATS_LATS1_ST	O95835	LATS1	O95835	LATS1	S464	S464Y	464	Missense	central	0	yes	0.003	0.000	EPSD	TCGA;ICGC;COSMIC	0.001	Loss
AGC_NDR_LATS_LATS1_ST	O95835	LATS1	O95835	LATS1	S633	R630H	630	Missense	distal	-3	no	0.003	0.000	EPSD	TCGA;ICGC	0.001	Loss
AGC_NDR_LATS_LATS1_ST	O95835	LATS1	O95835	LATS1	S635	R630H	630	Missense	distal	-5	no	0.001	0.002	EPSD	TCGA;ICGC	0.001	Up-regulation
AGC_NDR_LATS_LATS1_ST	O95835	LATS1	O95835	LATS1	S674	V671I	671	Missense	distal	-3	no	0.001	0.000	PhosphoSitePlus;EPSD	TCGA;ICGC;COSMIC	0.001	Loss
AGC_NDR_LATS_LATS1_ST	O95835	LATS1	O95835	LATS1	S859	R854K	854	Missense	distal	-5	no	0.001	0.000	EPSD	TCGA;ICGC;COSMIC	0.001	Loss
AGC_NDR_LATS_LATS1_ST	O95835	LATS1	O95835	LATS1	T913	L910S	910	Missense	distal	-3	no	0.002	0.001	EPSD	TCGA;ICGC;COSMIC	0.001	Down-regulation
AGC_NDR_LATS_LATS1_ST	O95835	LATS1	O95835	LATS1	T1012	H1007Y	1007	Missense	distal	-5	no	0.002	0.000	EPSD	TCGA;ICGC;COSMIC	0.001	Loss
AGC_NDR_LATS_LATS1_ST	P04049	RAF1	O95835	LATS1	S220	R215C	215	Missense	distal	-5	no	0.001	0.000	EPSD	TCGA;ICGC;COSMIC	0.001	Loss
AGC_NDR_LATS_LATS1_ST	P04049	RAF1	O95835	LATS1	S228	R223M	223	Missense	distal	-5	no	0.001	0.000	EPSD	TCGA;ICGC;COSMIC	0.001	Loss
AGC_NDR_LATS_LATS1_ST	P04049	RAF1	O95835	LATS1	S257	S257L	257	Missense	central	0	yes	0.002	0.000	EPSD	TCGA;COSMIC;GDSC;CCLE	0.001	Loss
AGC_NDR_LATS_LATS1_ST	P04049	RAF1	O95835	LATS1	S257	S257W	257	Missense	central	0	yes	0.002	0.000	EPSD	TCGA;COSMIC	0.001	Loss
AGC_NDR_LATS_LATS1_ST	P04049	RAF1	O95835	LATS1	S259	S259F	259	Missense	central	0	yes	0.004	0.000	PhosphoSitePlus	TCGA;COSMIC;GDSC;CCLE	0.001	Loss
AGC_NDR_LATS_LATS1_ST	P04049	RAF1	O95835	LATS1	T269	H264Y	264	Missense	distal	-5	no	0.002	0.000	EPSD	TCGA;COSMIC	0.001	Loss
AGC_NDR_LATS_LATS1_ST	P04049	RAF1	O95835	LATS1	S338	R333H	333	Missense	distal	-5	no	0.001	0.002	EPSD	TCGA;COSMIC	0.001	Up-regulation
AGC_NDR_LATS_LATS1_ST	P04049	RAF1	O95835	LATS1	S339	S339I	339	Missense	central	0	yes	0.003	0.000	EPSD	TCGA	0.001	Loss
AGC_NDR_LATS_LATS1_ST	P04049	RAF1	O95835	LATS1	S357	R354W	354	Missense	distal	-3	no	0.002	0.000	EPSD	TCGA;COSMIC	0.001	Loss
AGC_NDR_LATS_LATS1_ST	P04049	RAF1	O95835	LATS1	S359	R354W	354	Missense	distal	-5	no	0.001	0.000	EPSD	TCGA;COSMIC	0.001	Loss
AGC_NDR_LATS_LATS1_ST	Q02241	KIF23	O95835	LATS1	T13	R10W	10	Missense	distal	-3	no	0.002	0.000	EPSD	TCGA;ICGC;COSMIC	0.001	Loss
AGC_NDR_LATS_LATS1_ST	Q02241	KIF23	O95835	LATS1	T20	G17R	17	Missense	distal	-3	no	0.000	0.003	EPSD	TCGA;ICGC;COSMIC	0.001	Gain
AGC_NDR_LATS_LATS1_ST	Q02241	KIF23	O95835	LATS1	T56	Q53R	53	Missense	distal	-3	no	-0.001	0.002	EPSD	TCGA;ICGC;COSMIC	0.001	Gain
AGC_NDR_LATS_LATS1_ST	Q02241	KIF23	O95835	LATS1	S155	R150Q	150	Missense	distal	-5	no	0.001	0.000	EPSD	TCGA;ICGC;COSMIC	0.001	Loss
AGC_NDR_LATS_LATS1_ST	Q02241	KIF23	O95835	LATS1	S155	R150L	150	Missense	distal	-5	no	0.001	0.000	EPSD	TCGA;ICGC;COSMIC	0.001	Loss
AGC_NDR_LATS_LATS1_ST	Q02241	KIF23	O95835	LATS1	S298	S298F	298	Missense	central	0	yes	0.002	0.000	EPSD	TCGA;COSMIC	0.001	Loss
AGC_NDR_LATS_LATS1_ST	Q02241	KIF23	O95835	LATS1	S303	S298F	298	Missense	distal	-5	no	0.002	0.003	EPSD	TCGA;COSMIC	0.001	Up-regulation
AGC_NDR_LATS_LATS1_ST	Q02241	KIF23	O95835	LATS1	S716	R713H	713	Missense	distal	-3	no	0.005	0.002	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	0.001	Down-regulation
AGC_NDR_LATS_LATS1_ST	Q02241	KIF23	O95835	LATS1	S718	R713H	713	Missense	distal	-5	no	0.001	0.002	EPSD	TCGA;ICGC;COSMIC	0.001	Up-regulation
AGC_NDR_LATS_LATS1_ST	Q02241	KIF23	O95835	LATS1	S814	S814F	814	Missense	central	0	yes	0.005	0.000	PhosphoSitePlus;EPSD	TCGA;COSMIC	0.001	Loss
AGC_NDR_LATS_LATS1_ST	Q02241	KIF23	O95835	LATS1	S943	R940T	940	Missense	distal	-3	no	0.003	0.000	EPSD	TCGA;COSMIC	0.001	Loss
AGC_NDR_LATS_LATS1_ST	Q4VCS5	AMOT	O95835	LATS1	S175	R172H	172	Missense	distal	-3	no	0.005	0.002	PhosphoSitePlus	TCGA;ICGC	0.001	Down-regulation
AGC_NDR_LATS_LATS1_ST	Q4VCS5	AMOT	O95835	LATS1	T709	A704D	704	Missense	distal	-5	no	0.002	0.003	EPSD	TCGA;COSMIC	0.001	Up-regulation
AGC_NDR_LATS_LATS1_ST	Q4VCS5	AMOT	O95835	LATS1	T750	R747M	747	Missense	distal	-3	no	0.002	0.000	EPSD	TCGA;ICGC;COSMIC	0.001	Loss
AGC_NDR_LATS_LATS1_ST	Q4VCS5	AMOT	O95835	LATS1	T806	S803F	803	Missense	distal	-3	no	0.001	0.002	EPSD	TCGA;CCLE	0.001	Up-regulation
AGC_NDR_LATS_LATS1_ST	Q4VCS5	AMOT	O95835	LATS1	T806	H801Y	801	Missense	distal	-5	no	0.001	-0.001	EPSD	TCGA;COSMIC	0.001	Loss
AGC_NDR_LATS_LATS1_ST	Q4VCS5	AMOT	O95835	LATS1	T806	H801L	801	Missense	distal	-5	no	0.001	0.000	EPSD	TCGA;ICGC;COSMIC	0.001	Loss
AGC_NDR_LATS_LATS1_ST	Q4VCS5	AMOT	O95835	LATS1	S808	L805R	805	Missense	distal	-3	no	0.000	0.003	EPSD	TCGA;COSMIC	0.001	Gain
AGC_NDR_LATS_LATS1_ST	Q4VCS5	AMOT	O95835	LATS1	S847	S842L	842	Missense	distal	-5	no	0.000	0.001	EPSD	TCGA;COSMIC	0.001	Gain
AGC_NDR_LATS_LATS1_ST	Q4VCS5	AMOT	O95835	LATS1	S859	K856R	856	Missense	distal	-3	no	0.002	0.005	EPSD	TCGA;COSMIC	0.001	Up-regulation
AGC_NDR_LATS_LATS1_ST	Q9GZV5	WWTR1	O95835	LATS1	S89	H84D	84	Missense	distal	-5	no	0.005	0.003	PhosphoSitePlus	TCGA;ICGC;COSMIC	0.001	Down-regulation
AGC_NDR_LATS_LATS1_ST	Q9GZV5	WWTR1	O95835	LATS1	S89	S89W	89	Missense	central	0	yes	0.005	0.000	PhosphoSitePlus	TCGA;ICGC;COSMIC	0.001	Loss
AGC_NDR_LATS_LATS1_ST	Q9GZV5	WWTR1	O95835	LATS1	S93	S90P	90	Missense	distal	-3	no	0.001	0.002	EPSD	TCGA;ICGC;COSMIC	0.001	Up-regulation
AGC_NDR_LATS_LATS1_ST	Q9GZV5	WWTR1	O95835	LATS1	S174	Q179H	179	Missense	distal	5	no	0.002	0.001	EPSD	TCGA;ICGC;COSMIC	0.001	Down-regulation
AGC_NDR_LATS_LATS1_ST	Q9GZV5	WWTR1	O95835	LATS1	S174	V177L	177	Missense	distal	3	no	0.002	0.001	EPSD	TCGA;ICGC;COSMIC	0.001	Down-regulation
AGC_NDR_LATS_LATS1_ST	Q9GZV5	WWTR1	O95835	LATS1	S174	P178S	178	Missense	distal	4	no	0.002	0.001	EPSD	TCGA;ICGC;COSMIC	0.001	Down-regulation
AGC_NDR_LATS_LATS1_ST	Q9GZV5	WWTR1	O95835	LATS1	S174	V172I	172	Missense	proximal	-2	no	0.002	0.001	EPSD	TCGA;ICGC;COSMIC	0.001	Down-regulation
AGC_NDR_LATS_LATS1_ST	Q9GZV5	WWTR1	O95835	LATS1	S311	H306Y	306	Missense	distal	-5	no	0.005	0.003	EPSD	TCGA;ICGC;COSMIC	0.001	Down-regulation
TK_PDGFR_PDGFRB_Y	P09619	PDGFRB	P09619	PDGFRB	Y562	L555I	555	Missense	distal	-7	no	62.833	65.875	EPSD;PhosphoSitePlus	TCGA;ICGC	43.065	Up-regulation
TK_PDGFR_PDGFRB_Y	P09619	PDGFRB	P09619	PDGFRB	Y589	E594G	594	Missense	distal	5	no	60.161	50.596	EPSD	TCGA;ICGC;COSMIC	43.065	Down-regulation
TK_PDGFR_PDGFRB_Y	P09619	PDGFRB	P09619	PDGFRB	Y589	D590A	590	Missense	proximal	1	no	60.161	60.987	EPSD	TCGA;ICGC;COSMIC	43.065	Up-regulation
TK_PDGFR_PDGFRB_Y	P09619	PDGFRB	P09619	PDGFRB	Y686	G687E	687	Missense	proximal	1	no	43.099	37.739	EPSD	TCGA;ICGC;COSMIC	43.065	Loss
TK_PDGFR_PDGFRB_Y	P09619	PDGFRB	P09619	PDGFRB	Y686	R685C	685	Missense	proximal	-1	no	43.099	40.326	EPSD	TCGA;ICGC;COSMIC;GDSC	43.065	Loss
TK_PDGFR_PDGFRB_Y	P09619	PDGFRB	P09619	PDGFRB	Y686	G687R	687	Missense	proximal	1	no	43.099	39.480	EPSD	TCGA;ICGC;COSMIC	43.065	Loss
TK_PDGFR_PDGFRB_Y	P09619	PDGFRB	P09619	PDGFRB	Y716	R709L	709	Missense	distal	-7	no	64.419	62.117	EPSD	TCGA;ICGC;COSMIC	43.065	Down-regulation
TK_PDGFR_PDGFRB_Y	P09619	PDGFRB	P09619	PDGFRB	Y716	P711H	711	Missense	distal	-5	no	64.419	65.301	EPSD	TCGA;ICGC;COSMIC	43.065	Up-regulation
TK_PDGFR_PDGFRB_Y	P09619	PDGFRB	P09619	PDGFRB	Y716	A719V	719	Missense	distal	3	no	64.419	64.556	EPSD	TCGA;ICGC;COSMIC	43.065	Up-regulation
TK_PDGFR_PDGFRB_Y	P09619	PDGFRB	P09619	PDGFRB	Y740	D737N	737	Missense	distal	-3	no	66.534	61.741	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	43.065	Down-regulation
TK_PDGFR_PDGFRB_Y	P09619	PDGFRB	P09619	PDGFRB	Y740	G734W	734	Missense	distal	-6	no	66.534	69.776	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	43.065	Up-regulation
TK_PDGFR_PDGFRB_Y	P09619	PDGFRB	P09619	PDGFRB	Y751	Y751C	751	Missense	central	0	yes	65.534	0.000	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	43.065	Loss
TK_PDGFR_PDGFRB_Y	P09619	PDGFRB	P09619	PDGFRB	Y771	D776N	776	Missense	distal	5	no	66.784	57.699	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	43.065	Down-regulation
TK_PDGFR_PDGFRB_Y	P09619	PDGFRB	P09619	PDGFRB	Y771	Y778C	778	Missense	distal	7	no	66.784	64.923	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	43.065	Down-regulation
TK_PDGFR_PDGFRB_Y	P09619	PDGFRB	P09619	PDGFRB	Y775	D776N	776	Missense	proximal	1	no	66.836	66.664	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	43.065	Down-regulation
TK_PDGFR_PDGFRB_Y	P09619	PDGFRB	P09619	PDGFRB	Y775	Y778C	778	Missense	distal	3	no	66.836	66.377	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	43.065	Down-regulation
TK_PDGFR_PDGFRB_Y	P09619	PDGFRB	P09619	PDGFRB	Y778	D776N	776	Missense	proximal	-2	no	65.044	63.988	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	43.065	Down-regulation
TK_PDGFR_PDGFRB_Y	P09619	PDGFRB	P09619	PDGFRB	Y778	Y778C	778	Missense	central	0	yes	65.044	0.000	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	43.065	Loss
TK_PDGFR_PDGFRB_Y	P09619	PDGFRB	P09619	PDGFRB	Y857	R853W	853	Missense	distal	-4	no	68.992	67.954	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC;GDSC;CCLE	43.065	Down-regulation
TK_PDGFR_PDGFRB_Y	P09619	PDGFRB	P09619	PDGFRB	Y857	D850Y	850	Missense	distal	-7	no	68.992	70.786	EPSD;PhosphoSitePlus	TCGA;ICGC	43.065	Up-regulation
TK_PDGFR_PDGFRB_Y	P09619	PDGFRB	P09619	PDGFRB	Y1009	V1012M	1012	Missense	distal	3	no	67.172	67.671	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	43.065	Up-regulation
TK_PDGFR_PDGFRB_Y	P09619	PDGFRB	P09619	PDGFRB	Y1009	V1012L	1012	Missense	distal	3	no	67.172	67.201	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	43.065	Up-regulation
TK_PDGFR_PDGFRB_Y	P09619	PDGFRB	P09619	PDGFRB	Y1009	D1003N	1003	Missense	distal	-6	no	67.172	63.203	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	43.065	Down-regulation
TK_PDGFR_PDGFRB_Y	P09619	PDGFRB	P09619	PDGFRB	Y1009	T1004I	1004	Missense	distal	-5	no	67.172	67.508	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	43.065	Up-regulation
TK_PDGFR_PDGFRB_Y	P09619	PDGFRB	P09619	PDGFRB	Y1009	V1007I	1007	Missense	proximal	-2	no	67.172	59.757	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	43.065	Down-regulation
TK_PDGFR_PDGFRB_Y	P09619	PDGFRB	P09619	PDGFRB	Y1009	T1010A	1010	Missense	proximal	1	no	67.172	67.769	EPSD;PhosphoSitePlus	TCGA;ICGC	43.065	Up-regulation
TK_PDGFR_PDGFRB_Y	P09619	PDGFRB	P09619	PDGFRB	Y1021	D1018E	1018	Missense	distal	-3	no	59.451	51.884	PhosphoSitePlus;EPSD	TCGA;ICGC;COSMIC	43.065	Down-regulation
TK_PDGFR_PDGFRB_Y	P16234	PDGFRA	P09619	PDGFRB	Y555	E556K	556	Missense	proximal	1	no	48.071	48.939	EPSD	TCGA;ICGC;COSMIC	43.065	Up-regulation
TK_PDGFR_PDGFRB_Y	P16234	PDGFRA	P09619	PDGFRB	Y555	R558H	558	Missense	distal	3	no	48.071	48.115	EPSD	TCGA;ICGC;COSMIC	43.065	Up-regulation
TK_PDGFR_PDGFRB_Y	P16234	PDGFRA	P09619	PDGFRB	Y555	R558C	558	Missense	distal	3	no	48.071	47.957	EPSD	TCGA;ICGC;COSMIC	43.065	Down-regulation
TK_PDGFR_PDGFRB_Y	P16234	PDGFRA	P09619	PDGFRB	Y555	P553L	553	Missense	proximal	-2	no	48.071	43.600	EPSD	TCGA;ICGC;COSMIC	43.065	Down-regulation
TK_PDGFR_PDGFRB_Y	P16234	PDGFRA	P09619	PDGFRB	Y572	E571K	571	Missense	proximal	-1	no	50.468	47.186	EPSD	TCGA;ICGC;COSMIC	43.065	Down-regulation
TK_PDGFR_PDGFRB_Y	P16234	PDGFRA	P09619	PDGFRB	Y572	Y572C	572	Missense	central	0	yes	50.468	0.000	EPSD	TCGA;ICGC;COSMIC	43.065	Loss
TK_PDGFR_PDGFRB_Y	P16234	PDGFRA	P09619	PDGFRB	Y572	H570Y	570	Missense	proximal	-2	no	50.468	50.271	EPSD	TCGA;ICGC;COSMIC	43.065	Down-regulation
TK_PDGFR_PDGFRB_Y	P16234	PDGFRA	P09619	PDGFRB	Y572	E571D	571	Missense	proximal	-1	no	50.468	49.986	EPSD	TCGA;ICGC	43.065	Down-regulation
TK_PDGFR_PDGFRB_Y	P16234	PDGFRA	P09619	PDGFRB	Y572	P577L	577	Missense	distal	5	no	50.468	23.750	EPSD	TCGA;ICGC;COSMIC	43.065	Loss
TK_PDGFR_PDGFRB_Y	P16234	PDGFRA	P09619	PDGFRB	Y574	E571K	571	Missense	distal	-3	no	51.135	54.920	EPSD	TCGA;ICGC;COSMIC	43.065	Up-regulation
TK_PDGFR_PDGFRB_Y	P16234	PDGFRA	P09619	PDGFRB	Y574	Y572C	572	Missense	proximal	-2	no	51.135	46.442	EPSD	TCGA;ICGC;COSMIC	43.065	Down-regulation
TK_PDGFR_PDGFRB_Y	P16234	PDGFRA	P09619	PDGFRB	Y574	H570Y	570	Missense	distal	-4	no	51.135	51.428	EPSD	TCGA;ICGC;COSMIC	43.065	Up-regulation
TK_PDGFR_PDGFRB_Y	P16234	PDGFRA	P09619	PDGFRB	Y574	L580P	580	Missense	distal	6	no	51.135	53.930	EPSD	TCGA;ICGC;COSMIC	43.065	Up-regulation
TK_PDGFR_PDGFRB_Y	P16234	PDGFRA	P09619	PDGFRB	Y574	E571D	571	Missense	distal	-3	no	51.135	58.703	EPSD	TCGA;ICGC	43.065	Up-regulation
TK_PDGFR_PDGFRB_Y	P16234	PDGFRA	P09619	PDGFRB	Y574	P577L	577	Missense	distal	3	no	51.135	51.029	EPSD	TCGA;ICGC;COSMIC	43.065	Down-regulation
TK_PDGFR_PDGFRB_Y	P16234	PDGFRA	P09619	PDGFRB	Y582	L580P	580	Missense	proximal	-2	no	57.225	61.695	EPSD	TCGA;ICGC;COSMIC	43.065	Up-regulation
TK_PDGFR_PDGFRB_Y	P16234	PDGFRA	P09619	PDGFRB	Y582	R585I	585	Missense	distal	3	no	57.225	57.366	EPSD	TCGA;ICGC	43.065	Up-regulation
TK_PDGFR_PDGFRB_Y	P16234	PDGFRA	P09619	PDGFRB	Y582	P577L	577	Missense	distal	-5	no	57.225	59.212	EPSD	TCGA;ICGC;COSMIC	43.065	Up-regulation
TK_PDGFR_PDGFRB_Y	P16234	PDGFRA	P09619	PDGFRB	Y731	E726Q	726	Missense	distal	-5	no	55.105	55.666	EPSD	TCGA;ICGC;COSMIC	43.065	Up-regulation
TK_PDGFR_PDGFRB_Y	P16234	PDGFRA	P09619	PDGFRB	Y731	G729V	729	Missense	proximal	-2	no	55.105	54.792	EPSD	TCGA;ICGC;COSMIC	43.065	Down-regulation
TK_PDGFR_PDGFRB_Y	P16234	PDGFRA	P09619	PDGFRB	Y731	M734T	734	Missense	distal	3	no	55.105	54.994	EPSD	TCGA;ICGC;COSMIC	43.065	Down-regulation
TK_PDGFR_PDGFRB_Y	P16234	PDGFRA	P09619	PDGFRB	Y754	R748K	748	Missense	distal	-6	no	64.177	62.521	PhosphoSitePlus	TCGA;ICGC;COSMIC	43.065	Down-regulation
TK_PDGFR_PDGFRB_Y	P16234	PDGFRA	P09619	PDGFRB	Y849	D842Y	842	Missense	distal	-7	no	72.976	74.770	EPSD	TCGA;ICGC;COSMIC	43.065	Up-regulation
TK_PDGFR_PDGFRB_Y	P16234	PDGFRA	P09619	PDGFRB	Y849	S847L	847	Missense	proximal	-2	no	72.976	63.638	EPSD	TCGA;ICGC;COSMIC	43.065	Down-regulation
TK_PDGFR_PDGFRB_Y	P16234	PDGFRA	P09619	PDGFRB	Y849	S851L	851	Missense	proximal	2	no	72.976	62.937	EPSD	TCGA;ICGC;COSMIC	43.065	Down-regulation
TK_PDGFR_PDGFRB_Y	Q05397	PTK2	P09619	PDGFRB	Y5	H12Y	12	Missense	distal	7	no	52.065	53.480	PhosphoSitePlus;EPSD	TCGA;ICGC;COSMIC	43.065	Up-regulation
TK_PDGFR_PDGFRB_Y	Q05397	PTK2	P09619	PDGFRB	Y5	A2T	2	Missense	distal	-3	no	52.065	51.484	PhosphoSitePlus;EPSD	TCGA;ICGC;COSMIC	43.065	Down-regulation
TK_PDGFR_PDGFRB_Y	Q05397	PTK2	P09619	PDGFRB	Y194	V201I	201	Missense	distal	7	no	66.347	67.769	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	43.065	Up-regulation
TK_PDGFR_PDGFRB_Y	Q05397	PTK2	P09619	PDGFRB	Y720	S725F	725	Missense	distal	5	no	44.465	30.528	EPSD	TCGA;ICGC	43.065	Loss
TK_PDGFR_PDGFRB_Y	Q05397	PTK2	P09619	PDGFRB	Y720	P718L	718	Missense	proximal	-2	no	44.465	39.994	EPSD	TCGA;ICGC;COSMIC	43.065	Loss
TK_PDGFR_PDGFRB_Y	Q05397	PTK2	P09619	PDGFRB	Y720	P723L	723	Missense	distal	3	no	44.465	44.358	EPSD	TCGA;ICGC;COSMIC	43.065	Down-regulation
TK_PDGFR_PDGFRB_Y	Q05397	PTK2	P09619	PDGFRB	Y720	K714N	714	Missense	distal	-6	no	44.465	40.213	EPSD	TCGA;ICGC;COSMIC	43.065	Loss
TK_PDGFR_PDGFRB_Y	P42684	ABL2	P09619	PDGFRB	Y80	E74Q	74	Missense	distal	-6	no	43.485	41.232	EPSD	TCGA;ICGC;COSMIC	43.065	Loss
TK_PDGFR_PDGFRB_Y	P42684	ABL2	P09619	PDGFRB	Y139	Y139C	139	Missense	central	0	yes	63.428	0.000	EPSD;PhosphoSitePlus	TCGA;COSMIC	43.065	Loss
TK_PDGFR_PDGFRB_Y	P42684	ABL2	P09619	PDGFRB	Y139	G138D	138	Missense	proximal	-1	no	63.428	71.511	EPSD;PhosphoSitePlus	TCGA	43.065	Up-regulation
TK_PDGFR_PDGFRB_Y	P42684	ABL2	P09619	PDGFRB	Y161	S159N	159	Missense	proximal	-2	no	69.382	66.100	EPSD;PhosphoSitePlus	TCGA;COSMIC;CCLE	43.065	Down-regulation
TK_PDGFR_PDGFRB_Y	P42684	ABL2	P09619	PDGFRB	Y161	S167N	167	Missense	distal	6	no	69.382	68.975	EPSD;PhosphoSitePlus	TCGA;COSMIC	43.065	Down-regulation
TK_PDGFR_PDGFRB_Y	P42684	ABL2	P09619	PDGFRB	Y161	T163N	163	Missense	proximal	2	no	69.382	72.953	EPSD;PhosphoSitePlus	TCGA;COSMIC	43.065	Up-regulation
TK_PDGFR_PDGFRB_Y	P42684	ABL2	P09619	PDGFRB	Y161	L168Q	168	Missense	distal	7	no	69.382	71.162	EPSD;PhosphoSitePlus	TCGA;COSMIC	43.065	Up-regulation
TK_PDGFR_PDGFRB_Y	P42684	ABL2	P09619	PDGFRB	Y439	A443T	443	Missense	distal	4	no	62.128	62.151	EPSD	TCGA;COSMIC;CCLE	43.065	Up-regulation
TK_PDGFR_PDGFRB_Y	P42684	ABL2	P09619	PDGFRB	Y568	S562L	562	Missense	distal	-6	no	41.667	50.849	EPSD	TCGA;COSMIC;CCLE	43.065	Gain
TK_PDGFR_PDGFRB_Y	Q13769	THOC5	P09619	PDGFRB	Y225	L226M	226	Missense	proximal	1	no	69.391	66.657	PhosphoSitePlus	TCGA;ICGC;COSMIC	43.065	Down-regulation
TK_PDGFR_PDGFRB_Y	P19174	PLCG1	P09619	PDGFRB	Y472	M479I	479	Missense	distal	7	no	49.225	50.786	EPSD	TCGA;ICGC;COSMIC	43.065	Up-regulation
TK_PDGFR_PDGFRB_Y	P19174	PLCG1	P09619	PDGFRB	Y518	K516N	516	Missense	proximal	-2	no	47.017	49.738	EPSD	TCGA	43.065	Up-regulation
TK_PDGFR_PDGFRB_Y	P19174	PLCG1	P09619	PDGFRB	Y833	Y833C	833	Missense	central	0	yes	46.545	0.000	EPSD	TCGA;ICGC;COSMIC	43.065	Loss
TK_PDGFR_PDGFRB_Y	P19174	PLCG1	P09619	PDGFRB	Y977	Y977C	977	Missense	central	0	yes	51.813	0.000	EPSD	TCGA;ICGC;COSMIC	43.065	Loss
TK_PDGFR_PDGFRB_Y	P19174	PLCG1	P09619	PDGFRB	Y977	R978W	978	Missense	proximal	1	no	51.813	50.500	EPSD	TCGA;ICGC;COSMIC	43.065	Down-regulation
TK_PDGFR_PDGFRB_Y	P19174	PLCG1	P09619	PDGFRB	Y977	S982F	982	Missense	distal	5	no	51.813	37.876	EPSD	TCGA;ICGC;COSMIC	43.065	Loss
TK_PDGFR_PDGFRB_Y	P06241	FYN	P09619	PDGFRB	Y28	R29G	29	Missense	proximal	1	no	53.550	57.168	PhosphoSitePlus	TCGA;ICGC;COSMIC	43.065	Up-regulation
TK_PDGFR_PDGFRB_Y	P06241	FYN	P09619	PDGFRB	Y28	Y30C	30	Missense	proximal	2	no	53.550	49.115	PhosphoSitePlus	TCGA;ICGC;COSMIC;GDSC;CCLE	43.065	Down-regulation
TK_PDGFR_PDGFRB_Y	P06241	FYN	P09619	PDGFRB	Y339	P337S	337	Missense	proximal	-2	no	38.377	43.246	EPSD	TCGA;COSMIC	43.065	Gain
TK_PDGFR_PDGFRB_Y	P06241	FYN	P09619	PDGFRB	Y420	A426T	426	Missense	distal	6	no	70.746	70.456	EPSD	TCGA;COSMIC	43.065	Down-regulation
TK_PDGFR_PDGFRB_Y	Q07912	TNK2	P09619	PDGFRB	Y518	G511D	511	Missense	distal	-7	no	49.239	47.574	EPSD	TCGA;COSMIC	43.065	Down-regulation
TK_PDGFR_PDGFRB_Y	Q07912	TNK2	P09619	PDGFRB	Y518	G511S	511	Missense	distal	-7	no	49.239	49.737	EPSD	TCGA;COSMIC	43.065	Up-regulation
TK_PDGFR_PDGFRB_Y	P12931	SRC	P09619	PDGFRB	Y419	A425V	425	Missense	distal	6	no	73.742	74.744	PhosphoSitePlus	TCGA;ICGC;COSMIC;CCLE	43.065	Up-regulation
TK_FGFR_FGFR4_Y	P22455	FGFR4	P22455	FGFR4	Y642	K645E	645	Missense	distal	3	no	4.747	4.762	EPSD	TCGA;COSMIC	1.608	Up-regulation
TK_FGFR_FGFR4_Y	P22455	FGFR4	P22455	FGFR4	Y643	R650C	650	Missense	distal	7	no	4.973	4.789	EPSD	TCGA;COSMIC	1.608	Down-regulation
TK_FGFR_FGFR4_Y	P22455	FGFR4	P22455	FGFR4	Y643	K645E	645	Missense	proximal	2	no	4.973	4.772	EPSD	TCGA;COSMIC	1.608	Down-regulation
TK_FGFR_FGFR4_Y	P22455	FGFR4	P22455	FGFR4	Y754	V750I	750	Missense	distal	-4	no	4.451	4.200	PhosphoSitePlus	TCGA;COSMIC	1.608	Down-regulation
TK_FGFR_FGFR4_Y	P22455	FGFR4	P22455	FGFR4	Y754	E752K	752	Missense	proximal	-2	no	4.451	4.446	PhosphoSitePlus	TCGA;COSMIC	1.608	Down-regulation
TK_FGFR_FGFR4_Y	P22455	FGFR4	P22455	FGFR4	Y754	D756N	756	Missense	proximal	2	no	4.451	4.063	PhosphoSitePlus	TCGA;COSMIC	1.608	Down-regulation
TK_FGFR_FGFR4_Y	P22455	FGFR4	P22455	FGFR4	Y754	T760A	760	Missense	distal	6	no	4.451	4.411	PhosphoSitePlus	TCGA;COSMIC	1.608	Down-regulation
CMGC_CDK_CDK7_CDK7_ST	P21127	CDK11B	P50613	CDK7	S38	R34C	34	Missense	distal	-4	no	14.733	14.685	EPSD	TCGA;ICGC;COSMIC;GDSC	13.598	Down-regulation
CMGC_CDK_CDK7_CDK7_ST	P21127	CDK11B	P50613	CDK7	S38	R45L	45	Missense	distal	7	no	14.733	11.139	EPSD	TCGA;ICGC;COSMIC	13.598	Loss
CMGC_CDK_CDK7_CDK7_ST	P21127	CDK11B	P50613	CDK7	S38	N37K	37	Missense	proximal	-1	no	14.733	14.253	EPSD	TCGA;ICGC	13.598	Down-regulation
CMGC_CDK_CDK7_CDK7_ST	P21127	CDK11B	P50613	CDK7	T61	D55N	55	Missense	distal	-6	no	18.051	17.938	EPSD	TCGA;ICGC;COSMIC	13.598	Down-regulation
CMGC_CDK_CDK7_CDK7_ST	P21127	CDK11B	P50613	CDK7	S65	D71H	71	Missense	distal	6	no	12.575	13.976	EPSD	TCGA;ICGC;COSMIC	13.598	Gain
CMGC_CDK_CDK7_CDK7_ST	P21127	CDK11B	P50613	CDK7	S65	S72F	72	Missense	distal	7	no	12.575	17.397	EPSD	TCGA;ICGC;COSMIC	13.598	Gain
CMGC_CDK_CDK7_CDK7_ST	P21127	CDK11B	P50613	CDK7	S398	G394V	394	Missense	distal	-4	no	17.481	17.016	EPSD	TCGA;COSMIC	13.598	Down-regulation
CMGC_CDK_CDK7_CDK7_ST	P49736	MCM2	P50613	CDK7	S5	E3K	3	Missense	proximal	-2	no	15.526	15.655	PhosphoSitePlus;EPSD	TCGA;ICGC	13.598	Up-regulation
CMGC_CDK_CDK7_CDK7_ST	P49736	MCM2	P50613	CDK7	S5	T9I	9	Missense	distal	4	no	15.526	15.281	PhosphoSitePlus;EPSD	TCGA;ICGC;COSMIC	13.598	Down-regulation
CMGC_CDK_CDK7_CDK7_ST	P49736	MCM2	P50613	CDK7	S13	R18W	18	Missense	distal	5	no	15.751	14.436	EPSD;PhosphoSitePlus	TCGA;ICGC	13.598	Down-regulation
CMGC_CDK_CDK7_CDK7_ST	P49736	MCM2	P50613	CDK7	S13	T9I	9	Missense	distal	-4	no	15.751	16.289	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	13.598	Up-regulation
CMGC_CDK_CDK7_CDK7_ST	P49736	MCM2	P50613	CDK7	S27	D22G	22	Missense	distal	-5	no	18.849	18.164	EPSD;PhosphoSitePlus	TCGA;ICGC	13.598	Down-regulation
CMGC_CDK_CDK7_CDK7_ST	P49736	MCM2	P50613	CDK7	S40	D36N	36	Missense	distal	-4	no	22.651	22.529	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	13.598	Down-regulation
CMGC_CDK_CDK7_CDK7_ST	P49736	MCM2	P50613	CDK7	S40	L38I	38	Missense	proximal	-2	no	22.651	22.531	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	13.598	Down-regulation
CMGC_CDK_CDK7_CDK7_ST	P49736	MCM2	P50613	CDK7	S41	D36N	36	Missense	distal	-5	no	22.804	21.943	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	13.598	Down-regulation
CMGC_CDK_CDK7_CDK7_ST	P49736	MCM2	P50613	CDK7	S41	L38I	38	Missense	distal	-3	no	22.804	21.460	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	13.598	Down-regulation
CMGC_CDK_CDK7_CDK7_ST	P49736	MCM2	P50613	CDK7	S53	D51H	51	Missense	proximal	-2	no	21.071	21.056	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	13.598	Down-regulation
CMGC_CDK_CDK7_CDK7_ST	P49736	MCM2	P50613	CDK7	S53	E50D	50	Missense	distal	-3	no	21.071	16.042	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	13.598	Down-regulation
CMGC_CDK_CDK7_CDK7_ST	P49736	MCM2	P50613	CDK7	S108	E111G	111	Missense	distal	3	no	26.698	26.592	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	13.598	Down-regulation
CMGC_CDK_CDK7_CDK7_ST	P49736	MCM2	P50613	CDK7	S139	R146H	146	Missense	distal	7	no	21.705	19.770	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	13.598	Down-regulation
CMGC_CDK_CDK7_CDK7_ST	P49736	MCM2	P50613	CDK7	S139	E145K	145	Missense	distal	6	no	21.705	20.830	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	13.598	Down-regulation
CMGC_CDK_CDK7_CDK7_ST	P49736	MCM2	P50613	CDK7	S139	R132H	132	Missense	distal	-7	no	21.705	22.462	EPSD;PhosphoSitePlus	TCGA;ICGC;CCLE	13.598	Up-regulation
CMGC_CDK_CDK7_CDK7_ST	P49736	MCM2	P50613	CDK7	S381	P382S	382	Missense	proximal	1	no	17.069	8.536	EPSD	TCGA;ICGC	13.598	Loss
CMGC_CDK_CDK7_CDK7_ST	P49736	MCM2	P50613	CDK7	S813	A819S	819	Missense	distal	6	no	17.979	16.300	EPSD	TCGA;ICGC;COSMIC	13.598	Down-regulation
CMGC_CDK_CDK7_CDK7_ST	P49736	MCM2	P50613	CDK7	S813	S813R	813	Missense	central	0	yes	17.979	0.000	EPSD	TCGA;ICGC;COSMIC	13.598	Loss
CMGC_CDK_CDK7_CDK7_ST	P49736	MCM2	P50613	CDK7	S813	R815H	815	Missense	proximal	2	no	17.979	18.290	EPSD	TCGA;ICGC;COSMIC	13.598	Up-regulation
CMGC_CDK_CDK7_CDK7_ST	P49736	MCM2	P50613	CDK7	S813	R812C	812	Missense	proximal	-1	no	17.979	18.103	EPSD	TCGA;ICGC;COSMIC;GDSC;CCLE	13.598	Up-regulation
CMGC_CDK_CDK7_CDK7_ST	P49736	MCM2	P50613	CDK7	S813	R812H	812	Missense	proximal	-1	no	17.979	17.982	EPSD	TCGA;ICGC	13.598	Up-regulation
CMGC_CDK_CDK7_CDK7_ST	P24941	CDK2	P50613	CDK7	T41	T39I	39	Missense	proximal	-2	no	14.399	14.665	EPSD	TCGA	13.598	Up-regulation
CMGC_CDK_CDK7_CDK7_ST	P24941	CDK2	P50613	CDK7	T41	K34T	34	Missense	distal	-7	no	14.399	12.144	EPSD	TCGA;ICGC;COSMIC	13.598	Loss
CMGC_CDK_CDK7_CDK7_ST	P24941	CDK2	P50613	CDK7	S46	T39I	39	Missense	distal	-7	no	21.025	21.962	EPSD;PhosphoSitePlus	TCGA	13.598	Up-regulation
CMGC_CDK_CDK7_CDK7_ST	P24941	CDK2	P50613	CDK7	T160	V163M	163	Missense	distal	3	no	33.784	34.082	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	13.598	Up-regulation
CMGC_CDK_CDK7_CDK7_ST	P24941	CDK2	P50613	CDK7	T160	P155H	155	Missense	distal	-5	no	33.784	30.366	EPSD;PhosphoSitePlus	TCGA	13.598	Down-regulation
CMGC_CDK_CDK7_CDK7_ST	P24941	CDK2	P50613	CDK7	T165	V163M	163	Missense	proximal	-2	no	21.011	20.912	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	13.598	Down-regulation
CMGC_CDK_CDK7_CDK7_ST	P24941	CDK2	P50613	CDK7	T165	P171S	171	Missense	distal	6	no	21.011	20.645	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	13.598	Down-regulation
CMGC_CDK_CDK7_CDK7_ST	P24941	CDK2	P50613	CDK7	S207	E208D	208	Missense	proximal	1	no	14.875	10.264	EPSD	TCGA;COSMIC	13.598	Loss
CMGC_CDK_CDK7_CDK7_ST	P24941	CDK2	P50613	CDK7	S261	P254L	254	Missense	distal	-7	no	16.686	17.522	EPSD	TCGA;COSMIC	13.598	Up-regulation
CMGC_CDK_CDK7_CDK7_ST	P03372	ESR1	P50613	CDK7	S106	P113S	113	Missense	distal	7	no	17.012	12.085	EPSD	TCGA;ICGC;COSMIC	13.598	Loss
CMGC_CDK_CDK7_CDK7_ST	P03372	ESR1	P50613	CDK7	S118	P113S	113	Missense	distal	-5	no	23.487	23.640	PhosphoSitePlus	TCGA;ICGC;COSMIC	13.598	Up-regulation
CMGC_CDK_CDK7_CDK7_ST	P03372	ESR1	P50613	CDK7	T574	S575L	575	Missense	proximal	1	no	19.161	20.223	EPSD	TCGA;ICGC;COSMIC	13.598	Up-regulation
CMGC_CDK_CDK7_CDK7_ST	P03372	ESR1	P50613	CDK7	T574	K581T	581	Missense	distal	7	no	19.161	19.474	EPSD	TCGA;ICGC	13.598	Up-regulation
CMGC_CDK_CDK7_CDK7_ST	P03372	ESR1	P50613	CDK7	S575	S575L	575	Missense	central	0	yes	15.227	0.000	EPSD	TCGA;ICGC;COSMIC	13.598	Loss
CMGC_CDK_CDK7_CDK7_ST	P03372	ESR1	P50613	CDK7	S575	K581T	581	Missense	distal	6	no	15.227	14.988	EPSD	TCGA;ICGC	13.598	Down-regulation
CMGC_CDK_CDK7_CDK7_ST	Q00534	CDK6	P50613	CDK7	T177	V181D	181	Missense	distal	4	no	29.096	31.981	PhosphoSitePlus	TCGA;ICGC;COSMIC	13.598	Up-regulation
CMGC_CDK_CDK7_CDK7_ST	Q00534	CDK6	P50613	CDK7	S290	A291T	291	Missense	proximal	1	no	5.138	16.731	EPSD	TCGA;ICGC;COSMIC	13.598	Gain
CMGC_CDK_CDK7_CDK7_ST	Q00534	CDK6	P50613	CDK7	S317	E322D	322	Missense	distal	5	no	14.253	14.424	EPSD	TCGA;ICGC;COSMIC	13.598	Up-regulation
CMGC_CDK_CDK7_CDK7_ST	Q00534	CDK6	P50613	CDK7	S317	T320I	320	Missense	distal	3	no	14.253	13.876	EPSD	TCGA;ICGC;COSMIC	13.598	Down-regulation
CMGC_CDK_CDK7_CDK7_ST	P04637	TP53	P50613	CDK7	S33	P27S	27	Missense	distal	-6	no	20.872	21.271	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	13.598	Up-regulation
CMGC_CDK_CDK7_CDK7_ST	P04637	TP53	P50613	CDK7	S33	P27L	27	Missense	distal	-6	no	20.872	20.851	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC;GDSC;CCLE	13.598	Down-regulation
CMGC_CDK_CDK7_CDK7_ST	P04637	TP53	P50613	CDK7	S46	D48N	48	Missense	proximal	2	no	15.372	14.470	EPSD	TCGA;ICGC;COSMIC;GDSC;CCLE	13.598	Down-regulation
CMGC_CDK_CDK7_CDK7_ST	P04637	TP53	P50613	CDK7	T81	A79V	79	Missense	proximal	-2	no	16.811	16.505	EPSD	TCGA;ICGC;COSMIC	13.598	Down-regulation
CMGC_CDK_CDK7_CDK7_ST	P04637	TP53	P50613	CDK7	T81	P77L	77	Missense	distal	-4	no	16.811	16.844	EPSD	TCGA;ICGC;COSMIC	13.598	Up-regulation
CMGC_CDK_CDK7_CDK7_ST	P04637	TP53	P50613	CDK7	T81	P82L	82	Missense	proximal	1	no	16.811	9.340	EPSD	TCGA;ICGC;COSMIC	13.598	Loss
CMGC_CDK_CDK7_CDK7_ST	P04637	TP53	P50613	CDK7	T81	A74T	74	Missense	distal	-7	no	16.811	18.629	EPSD	TCGA;ICGC;COSMIC	13.598	Up-regulation
CMGC_CDK_CDK7_CDK7_ST	P04637	TP53	P50613	CDK7	S127	K132N	132	Missense	distal	5	no	17.259	17.715	EPSD	TCGA;ICGC;COSMIC;GDSC;CCLE	13.598	Up-regulation
CMGC_CDK_CDK7_CDK7_ST	P04637	TP53	P50613	CDK7	S127	S121Y	121	Missense	distal	-6	no	17.259	16.740	EPSD	TCGA;ICGC;COSMIC	13.598	Down-regulation
CMGC_CDK_CDK7_CDK7_ST	P04637	TP53	P50613	CDK7	S127	M133K	133	Missense	distal	6	no	17.259	16.318	EPSD	TCGA;ICGC;COSMIC;CCLE	13.598	Down-regulation
CMGC_CDK_CDK7_CDK7_ST	P04637	TP53	P50613	CDK7	S127	K132E	132	Missense	distal	5	no	17.259	17.854	EPSD	TCGA;ICGC;COSMIC;GDSC;CCLE	13.598	Up-regulation
CMGC_CDK_CDK7_CDK7_ST	P04637	TP53	P50613	CDK7	S127	Y126C	126	Missense	proximal	-1	no	17.259	16.998	EPSD	TCGA;ICGC;COSMIC;GDSC	13.598	Down-regulation
CMGC_CDK_CDK7_CDK7_ST	P04637	TP53	P50613	CDK7	S127	S127P	127	Missense	central	0	yes	17.259	0.000	EPSD	TCGA;ICGC;COSMIC;GDSC;CCLE	13.598	Loss
CMGC_CDK_CDK7_CDK7_ST	P04637	TP53	P50613	CDK7	S127	Y126N	126	Missense	proximal	-1	no	17.259	17.346	EPSD	TCGA;ICGC;COSMIC	13.598	Up-regulation
CMGC_CDK_CDK7_CDK7_ST	P04637	TP53	P50613	CDK7	S127	L130V	130	Missense	distal	3	no	17.259	17.408	EPSD	TCGA;ICGC;COSMIC;GDSC;CCLE	13.598	Up-regulation
CMGC_CDK_CDK7_CDK7_ST	P04637	TP53	P50613	CDK7	S127	K132T	132	Missense	distal	5	no	17.259	16.735	EPSD	TCGA;ICGC;COSMIC;GDSC;CCLE	13.598	Down-regulation
CMGC_CDK_CDK7_CDK7_ST	P04637	TP53	P50613	CDK7	S127	S127Y	127	Missense	central	0	yes	17.259	0.000	EPSD	TCGA;ICGC;COSMIC	13.598	Loss
CMGC_CDK_CDK7_CDK7_ST	P04637	TP53	P50613	CDK7	S127	S127F	127	Missense	central	0	yes	17.259	0.000	EPSD	TCGA;ICGC;COSMIC;CCLE	13.598	Loss
CMGC_CDK_CDK7_CDK7_ST	P04637	TP53	P50613	CDK7	S127	M133R	133	Missense	distal	6	no	17.259	17.420	EPSD	TCGA;ICGC;COSMIC	13.598	Up-regulation
CMGC_CDK_CDK7_CDK7_ST	P04637	TP53	P50613	CDK7	S127	K132R	132	Missense	distal	5	no	17.259	15.909	EPSD	TCGA;ICGC;COSMIC;GDSC;CCLE	13.598	Down-regulation
CMGC_CDK_CDK7_CDK7_ST	P04637	TP53	P50613	CDK7	S127	F134L	134	Missense	distal	7	no	17.259	12.692	EPSD	TCGA;ICGC;COSMIC;CCLE	13.598	Loss
CMGC_CDK_CDK7_CDK7_ST	P04637	TP53	P50613	CDK7	S127	Y126S	126	Missense	proximal	-1	no	17.259	17.347	EPSD	TCGA;ICGC;COSMIC	13.598	Up-regulation
CMGC_CDK_CDK7_CDK7_ST	P04637	TP53	P50613	CDK7	S127	L130P	130	Missense	distal	3	no	17.259	18.267	EPSD	TCGA;ICGC;COSMIC	13.598	Up-regulation
CMGC_CDK_CDK7_CDK7_ST	P04637	TP53	P50613	CDK7	S127	L130F	130	Missense	distal	3	no	17.259	18.175	EPSD	TCGA;ICGC;COSMIC;CCLE	13.598	Up-regulation
CMGC_CDK_CDK7_CDK7_ST	P04637	TP53	P50613	CDK7	S127	F134V	134	Missense	distal	7	no	17.259	14.909	EPSD	TCGA;ICGC;COSMIC	13.598	Down-regulation
CMGC_CDK_CDK7_CDK7_ST	P04637	TP53	P50613	CDK7	S127	T125M	125	Missense	proximal	-2	no	17.259	17.147	EPSD	TCGA;ICGC;COSMIC;GDSC	13.598	Down-regulation
CMGC_CDK_CDK7_CDK7_ST	P04637	TP53	P50613	CDK7	S127	Y126D	126	Missense	proximal	-1	no	17.259	16.941	EPSD	TCGA;ICGC;COSMIC;GDSC	13.598	Down-regulation
CMGC_CDK_CDK7_CDK7_ST	P04637	TP53	P50613	CDK7	S127	K120E	120	Missense	distal	-7	no	17.259	15.608	EPSD	TCGA;ICGC;COSMIC	13.598	Down-regulation
CMGC_CDK_CDK7_CDK7_ST	P04637	TP53	P50613	CDK7	S127	N131S	131	Missense	distal	4	no	17.259	15.667	EPSD	TCGA;ICGC;COSMIC	13.598	Down-regulation
CMGC_CDK_CDK7_CDK7_ST	P04637	TP53	P50613	CDK7	S127	T125P	125	Missense	proximal	-2	no	17.259	17.428	EPSD	TCGA;ICGC;COSMIC;CCLE	13.598	Up-regulation
CMGC_CDK_CDK7_CDK7_ST	P04637	TP53	P50613	CDK7	S127	S127C	127	Missense	central	0	yes	17.259	0.000	EPSD	TCGA;ICGC;COSMIC;CCLE	13.598	Loss
CMGC_CDK_CDK7_CDK7_ST	P04637	TP53	P50613	CDK7	S127	N131I	131	Missense	distal	4	no	17.259	15.807	EPSD	TCGA;ICGC;COSMIC	13.598	Down-regulation
CMGC_CDK_CDK7_CDK7_ST	P04637	TP53	P50613	CDK7	S127	Y126H	126	Missense	proximal	-1	no	17.259	16.877	EPSD	TCGA;ICGC;COSMIC;GDSC	13.598	Down-regulation
CMGC_CDK_CDK7_CDK7_ST	P04637	TP53	P50613	CDK7	S127	K132Q	132	Missense	distal	5	no	17.259	18.444	EPSD	TCGA;ICGC;COSMIC;GDSC;CCLE	13.598	Up-regulation
CMGC_CDK_CDK7_CDK7_ST	P04637	TP53	P50613	CDK7	S127	L130R	130	Missense	distal	3	no	17.259	18.221	EPSD	TCGA;ICGC;COSMIC;CCLE	13.598	Up-regulation
CMGC_CDK_CDK7_CDK7_ST	P04637	TP53	P50613	CDK7	T150	V157F	157	Missense	distal	7	no	11.571	13.921	EPSD	TCGA;ICGC;COSMIC;GDSC;CCLE	13.598	Gain
CMGC_CDK_CDK7_CDK7_ST	P04637	TP53	P50613	CDK7	T155	A159P	159	Missense	distal	4	no	12.335	13.633	EPSD	TCGA;ICGC;COSMIC;CCLE	13.598	Gain
CMGC_CDK_CDK7_CDK7_ST	P04637	TP53	P50613	CDK7	T155	R156P	156	Missense	proximal	1	no	12.335	21.914	EPSD	TCGA;ICGC;COSMIC;GDSC;CCLE	13.598	Gain
CMGC_CDK_CDK7_CDK7_ST	P04637	TP53	P50613	CDK7	S215	V216E	216	Missense	proximal	1	no	7.716	16.877	EPSD	TCGA;ICGC;COSMIC	13.598	Gain
CMGC_CDK_CDK7_CDK7_ST	P04637	TP53	P50613	CDK7	S315	K319N	319	Missense	distal	4	no	14.594	15.097	EPSD	TCGA;ICGC;COSMIC	13.598	Up-regulation
CMGC_CDK_CDK7_CDK7_ST	P04637	TP53	P50613	CDK7	S315	K320E	320	Missense	distal	5	no	14.594	15.190	EPSD	TCGA;ICGC;COSMIC	13.598	Up-regulation
CMGC_CDK_CDK7_CDK7_ST	P04637	TP53	P50613	CDK7	S315	S315C	315	Missense	central	0	yes	14.594	0.000	EPSD	TCGA;ICGC;COSMIC	13.598	Loss
CMGC_CDK_CDK7_CDK7_ST	P04637	TP53	P50613	CDK7	S371	S376C	376	Missense	distal	5	no	20.263	18.787	PhosphoSitePlus;EPSD	TCGA;ICGC;COSMIC	13.598	Down-regulation
CMGC_CDK_CDK7_CDK7_ST	P04637	TP53	P50613	CDK7	S371	Q375K	375	Missense	distal	4	no	20.263	18.105	PhosphoSitePlus;EPSD	TCGA;ICGC;COSMIC	13.598	Down-regulation
CMGC_CDK_CDK7_CDK7_ST	P04637	TP53	P50613	CDK7	S376	S376C	376	Missense	central	0	yes	20.595	0.000	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	13.598	Loss
CMGC_CDK_CDK7_CDK7_ST	P04637	TP53	P50613	CDK7	S376	Q375K	375	Missense	proximal	-1	no	20.595	20.144	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	13.598	Down-regulation
CMGC_CDK_CDK7_CDK7_ST	P04637	TP53	P50613	CDK7	S378	S376C	376	Missense	proximal	-2	no	19.642	19.022	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	13.598	Down-regulation
CMGC_CDK_CDK7_CDK7_ST	P04637	TP53	P50613	CDK7	S378	Q375K	375	Missense	distal	-3	no	19.642	20.631	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	13.598	Up-regulation
CMGC_CDK_CDK7_CDK7_ST	O00267	SUPT5H	P50613	CDK7	S36	R31Q	31	Missense	distal	-5	no	13.744	13.666	EPSD	TCGA;ICGC;COSMIC	13.598	Down-regulation
CMGC_CDK_CDK7_CDK7_ST	O00267	SUPT5H	P50613	CDK7	S36	R30W	30	Missense	distal	-6	no	13.744	12.739	EPSD	TCGA;ICGC;COSMIC	13.598	Loss
CMGC_CDK_CDK7_CDK7_ST	O00267	SUPT5H	P50613	CDK7	S195	T192S	192	Missense	distal	-3	no	16.092	15.907	EPSD	TCGA;ICGC;COSMIC	13.598	Down-regulation
CMGC_CDK_CDK7_CDK7_ST	O00267	SUPT5H	P50613	CDK7	S195	R198H	198	Missense	distal	3	no	16.092	15.251	EPSD	TCGA;ICGC;COSMIC	13.598	Down-regulation
CMGC_CDK_CDK7_CDK7_ST	O00267	SUPT5H	P50613	CDK7	S195	A191D	191	Missense	distal	-4	no	16.092	16.563	EPSD	TCGA;ICGC	13.598	Up-regulation
CMGC_CDK_CDK7_CDK7_ST	O00267	SUPT5H	P50613	CDK7	S195	A202T	202	Missense	distal	7	no	16.092	13.986	EPSD	TCGA;ICGC;COSMIC	13.598	Down-regulation
CMGC_CDK_CDK7_CDK7_ST	O00267	SUPT5H	P50613	CDK7	S375	F373L	373	Missense	proximal	-2	no	13.811	14.308	EPSD	TCGA;ICGC;COSMIC;GDSC;CCLE	13.598	Up-regulation
CMGC_CDK_CDK7_CDK7_ST	O00267	SUPT5H	P50613	CDK7	S375	A377T	377	Missense	proximal	2	no	13.811	14.537	EPSD	TCGA;ICGC;COSMIC;GDSC;CCLE	13.598	Up-regulation
CMGC_CDK_CDK7_CDK7_ST	O00267	SUPT5H	P50613	CDK7	S375	M378I	378	Missense	distal	3	no	13.811	13.776	EPSD	TCGA;ICGC;COSMIC	13.598	Down-regulation
CMGC_CDK_CDK7_CDK7_ST	O00267	SUPT5H	P50613	CDK7	S375	S379F	379	Missense	distal	4	no	13.811	14.997	EPSD	TCGA;ICGC	13.598	Up-regulation
CMGC_CDK_CDK7_CDK7_ST	O00267	SUPT5H	P50613	CDK7	S375	A380T	380	Missense	distal	5	no	13.811	12.233	EPSD	TCGA;ICGC;COSMIC	13.598	Loss
CMGC_CDK_CDK7_CDK7_ST	O00267	SUPT5H	P50613	CDK7	S686	F684C	684	Missense	proximal	-2	no	14.289	14.272	EPSD	TCGA;ICGC;COSMIC	13.598	Down-regulation
CMGC_CDK_CDK7_CDK7_ST	O00267	SUPT5H	P50613	CDK7	S763	Y765C	765	Missense	proximal	2	no	23.713	22.573	EPSD	TCGA;ICGC;COSMIC	13.598	Down-regulation
CMGC_CDK_CDK7_CDK7_ST	O00267	SUPT5H	P50613	CDK7	S763	R756Q	756	Missense	distal	-7	no	23.713	22.526	EPSD	TCGA;ICGC;COSMIC	13.598	Down-regulation
CMGC_CDK_CDK7_CDK7_ST	O00267	SUPT5H	P50613	CDK7	S763	T762I	762	Missense	proximal	-1	no	23.713	23.734	EPSD	TCGA;ICGC;COSMIC	13.598	Up-regulation
CMGC_CDK_CDK7_CDK7_ST	O00267	SUPT5H	P50613	CDK7	S763	R757H	757	Missense	distal	-6	no	23.713	23.001	EPSD	TCGA;ICGC;COSMIC	13.598	Down-regulation
CMGC_CDK_CDK7_CDK7_ST	O00267	SUPT5H	P50613	CDK7	T806	R813H	813	Missense	distal	7	no	16.696	14.761	EPSD	TCGA;ICGC;COSMIC;CCLE	13.598	Down-regulation
CMGC_CDK_CDK7_CDK7_ST	O00267	SUPT5H	P50613	CDK7	T806	S812C	812	Missense	distal	6	no	16.696	16.810	EPSD	TCGA;ICGC;COSMIC	13.598	Up-regulation
CMGC_CDK_CDK7_CDK7_ST	O00267	SUPT5H	P50613	CDK7	T806	S812N	812	Missense	distal	6	no	16.696	16.539	EPSD	TCGA;ICGC;COSMIC	13.598	Down-regulation
CMGC_CDK_CDK7_CDK7_ST	O00267	SUPT5H	P50613	CDK7	S812	R813H	813	Missense	proximal	1	no	14.513	12.654	EPSD	TCGA;ICGC;COSMIC;CCLE	13.598	Loss
CMGC_CDK_CDK7_CDK7_ST	O00267	SUPT5H	P50613	CDK7	S812	Q817H	817	Missense	distal	5	no	14.513	11.459	EPSD	TCGA;ICGC;COSMIC	13.598	Loss
CMGC_CDK_CDK7_CDK7_ST	O00267	SUPT5H	P50613	CDK7	S812	Q817K	817	Missense	distal	5	no	14.513	13.328	EPSD	TCGA;ICGC;COSMIC	13.598	Loss
CMGC_CDK_CDK7_CDK7_ST	O00267	SUPT5H	P50613	CDK7	S812	S812C	812	Missense	central	0	yes	14.513	0.000	EPSD	TCGA;ICGC;COSMIC	13.598	Loss
CMGC_CDK_CDK7_CDK7_ST	O00267	SUPT5H	P50613	CDK7	S812	S812N	812	Missense	central	0	yes	14.513	0.000	EPSD	TCGA;ICGC;COSMIC	13.598	Loss
CMGC_CDK_CDK7_CDK7_ST	O00267	SUPT5H	P50613	CDK7	T814	R813H	813	Missense	proximal	-1	no	14.065	14.067	EPSD	TCGA;ICGC;COSMIC;CCLE	13.598	Up-regulation
CMGC_CDK_CDK7_CDK7_ST	O00267	SUPT5H	P50613	CDK7	T814	Q817H	817	Missense	distal	3	no	14.065	13.061	EPSD	TCGA;ICGC;COSMIC	13.598	Loss
CMGC_CDK_CDK7_CDK7_ST	O00267	SUPT5H	P50613	CDK7	T814	Q817K	817	Missense	distal	3	no	14.065	13.616	EPSD	TCGA;ICGC;COSMIC	13.598	Down-regulation
CMGC_CDK_CDK7_CDK7_ST	O00267	SUPT5H	P50613	CDK7	T814	S812C	812	Missense	proximal	-2	no	14.065	13.445	EPSD	TCGA;ICGC;COSMIC	13.598	Loss
CMGC_CDK_CDK7_CDK7_ST	O00267	SUPT5H	P50613	CDK7	T814	S812N	812	Missense	proximal	-2	no	14.065	13.737	EPSD	TCGA;ICGC;COSMIC	13.598	Down-regulation
CMGC_CDK_CDK7_CDK7_ST	O00267	SUPT5H	P50613	CDK7	S867	N871K	871	Missense	distal	4	no	20.493	19.990	EPSD	TCGA;ICGC;COSMIC	13.598	Down-regulation
CMGC_CDK_CDK7_CDK7_ST	O00267	SUPT5H	P50613	CDK7	S897	S891F	891	Missense	distal	-6	no	15.862	15.447	EPSD	TCGA;ICGC;COSMIC	13.598	Down-regulation
CMGC_CDK_CDK7_CDK7_ST	O00267	SUPT5H	P50613	CDK7	S897	F890L	890	Missense	distal	-7	no	15.862	15.717	EPSD	TCGA;ICGC;COSMIC	13.598	Down-regulation
CMGC_CDK_CDK7_CDK7_ST	P50750	CDK9	P50613	CDK7	S175	F168S	168	Missense	distal	-7	no	21.983	18.925	PhosphoSitePlus	TCGA;ICGC;COSMIC	13.598	Down-regulation
CMGC_CDK_CDK7_CDK7_ST	P50750	CDK9	P50613	CDK7	T330	M335V	335	Missense	distal	5	no	14.167	13.351	EPSD	TCGA;ICGC;COSMIC	13.598	Loss
CMGC_CDK_CDK7_CDK7_ST	P50750	CDK9	P50613	CDK7	T362	E369Q	369	Missense	distal	7	no	15.027	14.434	EPSD	TCGA;ICGC;COSMIC	13.598	Down-regulation
CMGC_CDK_CDK7_CDK7_ST	P50750	CDK9	P50613	CDK7	T362	R358H	358	Missense	distal	-4	no	15.027	15.518	EPSD	TCGA;ICGC;COSMIC	13.598	Up-regulation
CMGC_CDK_CDK7_CDK7_ST	P24928	POLR2A	P50613	CDK7	S217	L215R	215	Missense	proximal	-2	no	15.595	15.168	EPSD	TCGA;ICGC;COSMIC	13.598	Down-regulation
CMGC_CDK_CDK7_CDK7_ST	P24928	POLR2A	P50613	CDK7	S217	E223K	223	Missense	distal	6	no	15.595	14.721	EPSD	TCGA;ICGC;COSMIC	13.598	Down-regulation
CMGC_CDK_CDK7_CDK7_ST	P24928	POLR2A	P50613	CDK7	S217	L215P	215	Missense	proximal	-2	no	15.595	15.379	EPSD	TCGA;ICGC	13.598	Down-regulation
CMGC_CDK_CDK7_CDK7_ST	P24928	POLR2A	P50613	CDK7	S217	R220Q	220	Missense	distal	3	no	15.595	15.758	EPSD	TCGA;ICGC	13.598	Up-regulation
CMGC_CDK_CDK7_CDK7_ST	P24928	POLR2A	P50613	CDK7	T1518	A1516V	1516	Missense	proximal	-2	no	14.700	14.394	EPSD	TCGA;ICGC	13.598	Down-regulation
CMGC_CDK_CDK7_CDK7_ST	P24928	POLR2A	P50613	CDK7	T1518	M1517V	1517	Missense	proximal	-1	no	14.700	14.478	EPSD	TCGA;ICGC	13.598	Down-regulation
CMGC_CDK_CDK7_CDK7_ST	P24928	POLR2A	P50613	CDK7	S1571	P1572L	1572	Missense	proximal	1	no	14.917	7.446	EPSD	TCGA;ICGC	13.598	Loss
CMGC_CDK_CDK7_CDK7_ST	P24928	POLR2A	P50613	CDK7	S1571	G1570S	1570	Missense	proximal	-1	no	14.917	15.504	EPSD	TCGA;ICGC	13.598	Up-regulation
CMGC_CDK_CDK7_CDK7_ST	P24928	POLR2A	P50613	CDK7	S1619	T1625A	1625	Missense	distal	6	no	22.614	24.324	EPSD;PhosphoSitePlus	TCGA;ICGC	13.598	Up-regulation
CMGC_CDK_CDK7_CDK7_ST	P24928	POLR2A	P50613	CDK7	S1621	T1625A	1625	Missense	distal	4	no	20.619	21.086	EPSD;PhosphoSitePlus	TCGA;ICGC	13.598	Up-regulation
CMGC_CDK_CDK7_CDK7_ST	P24928	POLR2A	P50613	CDK7	S1626	T1625A	1625	Missense	proximal	-1	no	14.394	14.581	EPSD	TCGA;ICGC	13.598	Up-regulation
CMGC_CDK_CDK7_CDK7_ST	P24928	POLR2A	P50613	CDK7	S1626	S1630Y	1630	Missense	distal	4	no	14.394	15.670	EPSD	TCGA	13.598	Up-regulation
CMGC_CDK_CDK7_CDK7_ST	P24928	POLR2A	P50613	CDK7	S1626	P1631S	1631	Missense	distal	5	no	14.394	15.779	EPSD	TCGA;ICGC	13.598	Up-regulation
CMGC_CDK_CDK7_CDK7_ST	P24928	POLR2A	P50613	CDK7	S1626	P1631L	1631	Missense	distal	5	no	14.394	14.810	EPSD	TCGA;ICGC	13.598	Up-regulation
CMGC_CDK_CDK7_CDK7_ST	P24928	POLR2A	P50613	CDK7	S1675	S1677N	1677	Missense	proximal	2	no	14.197	14.624	EPSD	TCGA;ICGC	13.598	Up-regulation
CMGC_CDK_CDK7_CDK7_ST	P24928	POLR2A	P50613	CDK7	S1682	S1677N	1677	Missense	distal	-5	no	14.197	11.340	EPSD	TCGA;ICGC	13.598	Loss
CMGC_CDK_CDK7_CDK7_ST	P24928	POLR2A	P50613	CDK7	S1689	T1695M	1695	Missense	distal	6	no	14.197	15.377	EPSD	TCGA;ICGC	13.598	Up-regulation
CMGC_CDK_CDK7_CDK7_ST	P24928	POLR2A	P50613	CDK7	S1696	T1702I	1702	Missense	distal	6	no	14.197	14.148	EPSD	TCGA;ICGC	13.598	Down-regulation
CMGC_CDK_CDK7_CDK7_ST	P24928	POLR2A	P50613	CDK7	S1696	T1702S	1702	Missense	distal	6	no	14.197	14.227	EPSD	TCGA;ICGC	13.598	Up-regulation
CMGC_CDK_CDK7_CDK7_ST	P24928	POLR2A	P50613	CDK7	S1696	T1695M	1695	Missense	proximal	-1	no	14.197	14.346	EPSD	TCGA;ICGC	13.598	Up-regulation
CMGC_CDK_CDK7_CDK7_ST	P24928	POLR2A	P50613	CDK7	S1696	S1700L	1700	Missense	distal	4	no	14.197	14.773	EPSD	TCGA;ICGC	13.598	Up-regulation
CMGC_CDK_CDK7_CDK7_ST	P24928	POLR2A	P50613	CDK7	S1703	T1702I	1702	Missense	proximal	-1	no	14.197	14.218	EPSD	TCGA;ICGC	13.598	Up-regulation
CMGC_CDK_CDK7_CDK7_ST	P24928	POLR2A	P50613	CDK7	S1703	T1702S	1702	Missense	proximal	-1	no	14.197	14.443	EPSD	TCGA;ICGC	13.598	Up-regulation
CMGC_CDK_CDK7_CDK7_ST	P24928	POLR2A	P50613	CDK7	S1703	S1700L	1700	Missense	distal	-3	no	14.197	14.645	EPSD	TCGA;ICGC	13.598	Up-regulation
CMGC_CDK_CDK7_CDK7_ST	P24928	POLR2A	P50613	CDK7	S1731	P1732L	1732	Missense	proximal	1	no	16.191	8.720	EPSD	TCGA;ICGC;CCLE	13.598	Loss
CMGC_CDK_CDK7_CDK7_ST	P24928	POLR2A	P50613	CDK7	S1731	S1735A	1735	Missense	distal	4	no	16.191	17.043	EPSD	TCGA;ICGC	13.598	Up-regulation
CMGC_CDK_CDK7_CDK7_ST	P24928	POLR2A	P50613	CDK7	S1738	T1744I	1744	Missense	distal	6	no	15.819	15.770	EPSD	TCGA;ICGC	13.598	Down-regulation
CMGC_CDK_CDK7_CDK7_ST	P24928	POLR2A	P50613	CDK7	S1738	S1745N	1745	Missense	distal	7	no	15.819	16.194	EPSD	TCGA;ICGC	13.598	Up-regulation
CMGC_CDK_CDK7_CDK7_ST	P24928	POLR2A	P50613	CDK7	S1738	P1732L	1732	Missense	distal	-6	no	15.819	15.798	EPSD	TCGA;ICGC;CCLE	13.598	Down-regulation
CMGC_CDK_CDK7_CDK7_ST	P24928	POLR2A	P50613	CDK7	S1738	S1735A	1735	Missense	distal	-3	no	15.819	17.770	EPSD	TCGA;ICGC	13.598	Up-regulation
CMGC_CDK_CDK7_CDK7_ST	P24928	POLR2A	P50613	CDK7	S1766	P1764S	1764	Missense	proximal	-2	no	17.842	18.164	EPSD	TCGA;ICGC	13.598	Up-regulation
CMGC_CDK_CDK7_CDK7_ST	P24928	POLR2A	P50613	CDK7	S1766	T1772I	1772	Missense	distal	6	no	17.842	17.794	EPSD	TCGA;ICGC	13.598	Down-regulation
CMGC_CDK_CDK7_CDK7_ST	P24928	POLR2A	P50613	CDK7	S1815	P1816A	1816	Missense	proximal	1	no	13.907	-4.847	EPSD	TCGA;ICGC	13.598	Loss
CMGC_CDK_CDK7_CDK7_ST	P24928	POLR2A	P50613	CDK7	S1815	Y1818C	1818	Missense	distal	3	no	13.907	13.731	EPSD	TCGA	13.598	Down-regulation
CMGC_CDK_CDK7_CDK7_ST	P24928	POLR2A	P50613	CDK7	S1815	P1809S	1809	Missense	distal	-6	no	13.907	14.306	EPSD	TCGA;ICGC	13.598	Up-regulation
CMGC_CDK_CDK7_CDK7_ST	P24928	POLR2A	P50613	CDK7	S1824	Y1818C	1818	Missense	distal	-6	no	13.930	13.621	EPSD	TCGA	13.598	Down-regulation
CMGC_CDK_CDK7_CDK7_ST	P24928	POLR2A	P50613	CDK7	T1840	S1845P	1845	Missense	distal	5	no	14.722	13.337	EPSD	TCGA;GDSC;CCLE	13.598	Loss
CMGC_CDK_CDK7_CDK7_ST	P24928	POLR2A	P50613	CDK7	T1840	S1845Y	1845	Missense	distal	5	no	14.722	12.249	EPSD	TCGA;ICGC	13.598	Loss
CMGC_CDK_CDK7_CDK7_ST	P24928	POLR2A	P50613	CDK7	S1845	S1845P	1845	Missense	central	0	yes	17.154	0.000	EPSD	TCGA;GDSC;CCLE	13.598	Loss
CMGC_CDK_CDK7_CDK7_ST	P24928	POLR2A	P50613	CDK7	S1845	S1845Y	1845	Missense	central	0	yes	17.154	0.000	EPSD	TCGA;ICGC	13.598	Loss
CMGC_CDK_CDK7_CDK7_ST	P24928	POLR2A	P50613	CDK7	S1850	S1857C	1857	Missense	distal	7	no	11.799	14.462	EPSD	TCGA;ICGC	13.598	Gain
CMGC_CDK_CDK7_CDK7_ST	P24928	POLR2A	P50613	CDK7	S1850	S1857F	1857	Missense	distal	7	no	11.799	16.621	EPSD	TCGA	13.598	Gain
CMGC_CDK_CDK7_CDK7_ST	P24928	POLR2A	P50613	CDK7	S1864	S1857C	1857	Missense	distal	-7	no	13.507	14.576	EPSD	TCGA;ICGC	13.598	Gain
CMGC_CDK_CDK7_CDK7_ST	P24928	POLR2A	P50613	CDK7	S1864	S1857F	1857	Missense	distal	-7	no	13.507	16.565	EPSD	TCGA	13.598	Gain
CMGC_CDK_CDK7_CDK7_ST	P24928	POLR2A	P50613	CDK7	S1878	Y1874H	1874	Missense	distal	-4	no	19.068	19.277	EPSD;PhosphoSitePlus	TCGA;ICGC	13.598	Up-regulation
CMGC_CDK_CDK7_CDK7_ST	P24928	POLR2A	P50613	CDK7	S1878	S1875L	1875	Missense	distal	-3	no	19.068	19.516	EPSD;PhosphoSitePlus	TCGA;ICGC	13.598	Up-regulation
CMGC_CDK_CDK7_CDK7_ST	P24928	POLR2A	P50613	CDK7	T1885	K1887N	1887	Missense	proximal	2	no	17.206	15.908	EPSD	TCGA;ICGC	13.598	Down-regulation
CMGC_CDK_CDK7_CDK7_ST	P24928	POLR2A	P50613	CDK7	T1894	T1898A	1898	Missense	distal	4	no	15.598	16.065	EPSD	TCGA;ICGC	13.598	Up-regulation
CMGC_CDK_CDK7_CDK7_ST	P24928	POLR2A	P50613	CDK7	T1894	S1896F	1896	Missense	proximal	2	no	15.598	17.259	EPSD	TCGA;ICGC	13.598	Up-regulation
CMGC_CDK_CDK7_CDK7_ST	P24928	POLR2A	P50613	CDK7	T1894	K1887N	1887	Missense	distal	-7	no	15.598	13.070	EPSD	TCGA;ICGC	13.598	Loss
CMGC_CDK_CDK7_CDK7_ST	P24928	POLR2A	P50613	CDK7	S1899	T1898A	1898	Missense	proximal	-1	no	18.354	18.541	EPSD	TCGA;ICGC	13.598	Up-regulation
CMGC_CDK_CDK7_CDK7_ST	P24928	POLR2A	P50613	CDK7	S1899	S1896F	1896	Missense	distal	-3	no	18.354	17.325	EPSD	TCGA;ICGC	13.598	Down-regulation
CMGC_CDK_CDK7_CDK7_ST	P24928	POLR2A	P50613	CDK7	S1913	P1907S	1907	Missense	distal	-6	no	13.635	14.034	EPSD	TCGA;ICGC	13.598	Up-regulation
CMGC_CDK_CDK7_CDK7_ST	P24928	POLR2A	P50613	CDK7	T1939	S1944F	1944	Missense	distal	5	no	19.787	17.583	EPSD	TCGA;ICGC	13.598	Down-regulation
CMGC_CDK_CDK7_CDK7_ST	P24928	POLR2A	P50613	CDK7	S1941	S1944F	1944	Missense	distal	3	no	17.772	18.427	EPSD	TCGA;ICGC	13.598	Up-regulation
CMGC_CDK_CDK7_CDK7_ST	P24928	POLR2A	P50613	CDK7	S1944	S1944F	1944	Missense	central	0	yes	15.729	0.000	EPSD	TCGA;ICGC	13.598	Loss
CMGC_CDK_CDK7_CDK7_ST	P24928	POLR2A	P50613	CDK7	S1948	S1944F	1944	Missense	distal	-4	no	15.454	16.226	EPSD	TCGA;ICGC	13.598	Up-regulation
CMGC_CDK_CDK7_CDK7_ST	P24928	POLR2A	P50613	CDK7	S1951	S1944F	1944	Missense	distal	-7	no	11.121	14.179	EPSD	TCGA;ICGC	13.598	Gain
CMGC_CDK_CDK7_CDK7_ST	P24928	POLR2A	P50613	CDK7	S1962	I1961M	1961	Missense	proximal	-1	no	20.322	20.449	EPSD	TCGA;ICGC	13.598	Up-regulation
CMGC_CDK_CDK7_CDK7_ST	P10276	RARA	P50613	CDK7	S74	P78S	78	Missense	distal	4	no	15.000	12.850	EPSD	TCGA;COSMIC	13.598	Loss
CMGC_CDK_CDK7_CDK7_ST	P10276	RARA	P50613	CDK7	S77	P78S	78	Missense	proximal	1	no	23.434	14.901	PhosphoSitePlus	TCGA;COSMIC	13.598	Down-regulation
CMGC_CDK_CDK7_CDK7_ST	P10276	RARA	P50613	CDK7	S219	R217S	217	Missense	proximal	-2	no	13.510	14.042	EPSD	TCGA;COSMIC	13.598	Gain
CMGC_CDK_CDK7_CDK7_ST	P10276	RARA	P50613	CDK7	S219	R217P	217	Missense	proximal	-2	no	13.510	13.721	EPSD	TCGA;COSMIC	13.598	Gain
CMGC_CDK_CDK7_CDK7_ST	P10276	RARA	P50613	CDK7	S219	R217G	217	Missense	proximal	-2	no	13.510	13.641	EPSD	TCGA;COSMIC	13.598	Gain
CMGC_CDK_CDK7_CDK7_ST	Q9H0D6	XRN2	P50613	CDK7	T439	I437L	437	Missense	proximal	-2	no	25.194	25.315	PhosphoSitePlus	TCGA;COSMIC	13.598	Up-regulation
CMGC_CDK_CDK7_CDK7_ST	Q9H0D6	XRN2	P50613	CDK7	S448	P449R	449	Missense	proximal	1	no	20.679	11.100	EPSD	TCGA;COSMIC	13.598	Loss
CMGC_CDK_CDK7_CDK7_ST	Q9H0D6	XRN2	P50613	CDK7	S475	S482Y	482	Missense	distal	7	no	15.716	16.965	EPSD	TCGA	13.598	Up-regulation
CMGC_CDK_CDK7_CDK7_ST	Q9H0D6	XRN2	P50613	CDK7	S475	F480L	480	Missense	distal	5	no	15.716	16.951	EPSD	TCGA;COSMIC	13.598	Up-regulation
CMGC_CDK_CDK7_CDK7_ST	Q9H0D6	XRN2	P50613	CDK7	S475	P472L	472	Missense	distal	-3	no	15.716	15.756	EPSD	TCGA;COSMIC	13.598	Up-regulation
CMGC_CDK_CDK7_CDK7_ST	Q9H0D6	XRN2	P50613	CDK7	S485	S482Y	482	Missense	distal	-3	no	16.627	16.812	EPSD	TCGA	13.598	Up-regulation
CMGC_CDK_CDK7_CDK7_ST	Q9H0D6	XRN2	P50613	CDK7	S485	F480L	480	Missense	distal	-5	no	16.627	17.085	EPSD	TCGA;COSMIC	13.598	Up-regulation
CMGC_CDK_CDK7_CDK7_ST	Q9H0D6	XRN2	P50613	CDK7	S485	S487P	487	Missense	proximal	2	no	16.627	17.124	EPSD	TCGA;COSMIC	13.598	Up-regulation
CMGC_CDK_CDK7_CDK7_ST	Q9H0D6	XRN2	P50613	CDK7	S485	G490A	490	Missense	distal	5	no	16.627	17.445	EPSD	TCGA;COSMIC	13.598	Up-regulation
CMGC_CDK_CDK7_CDK7_ST	Q9H0D6	XRN2	P50613	CDK7	S485	L489S	489	Missense	distal	4	no	16.627	16.051	EPSD	TCGA;COSMIC	13.598	Down-regulation
CMGC_CDK_CDK7_CDK7_ST	Q01094	E2F1	P50613	CDK7	T96	R91T	91	Missense	distal	-5	no	18.866	19.068	EPSD	TCGA;ICGC;COSMIC	13.598	Up-regulation
CMGC_CDK_CDK7_CDK7_ST	Q01094	E2F1	P50613	CDK7	T96	H98Y	98	Missense	proximal	2	no	18.866	18.252	EPSD	TCGA;ICGC;COSMIC	13.598	Down-regulation
CMGC_CDK_CDK7_CDK7_ST	Q01094	E2F1	P50613	CDK7	S131	R127H	127	Missense	distal	-4	no	13.151	13.642	EPSD	TCGA;ICGC;COSMIC;GDSC;CCLE	13.598	Gain
CMGC_CDK_CDK7_CDK7_ST	Q01094	E2F1	P50613	CDK7	T135	R138C	138	Missense	distal	3	no	19.767	19.560	EPSD	TCGA;ICGC;COSMIC;GDSC;CCLE	13.598	Down-regulation
CMGC_CDK_CDK7_CDK7_ST	Q01094	E2F1	P50613	CDK7	S313	I306V	306	Missense	distal	-7	no	13.787	12.310	EPSD	TCGA;ICGC;COSMIC	13.598	Loss
CMGC_CDK_CDK7_CDK7_ST	Q01094	E2F1	P50613	CDK7	T344	P346L	346	Missense	proximal	2	no	14.121	13.706	EPSD	TCGA;ICGC;COSMIC	13.598	Down-regulation
CMGC_CDK_CDK7_CDK7_ST	Q01094	E2F1	P50613	CDK7	S364	G363R	363	Missense	proximal	-1	no	15.270	15.384	EPSD	TCGA;ICGC;COSMIC	13.598	Up-regulation
CMGC_CDK_CDK7_CDK7_ST	Q01094	E2F1	P50613	CDK7	S403	H406Y	406	Missense	distal	3	no	24.807	25.617	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	13.598	Up-regulation
CMGC_CDK_CDK7_CDK7_ST	Q01094	E2F1	P50613	CDK7	T433	D426N	426	Missense	distal	-7	no	15.328	15.362	PhosphoSitePlus;EPSD	TCGA;ICGC	13.598	Up-regulation
CMGC_CDK_CDK7_CDK7_ST	P11802	CDK4	P50613	CDK7	S243	P250H	250	Missense	distal	7	no	15.913	12.900	EPSD	TCGA;COSMIC	13.598	Loss
CMGC_CDK_CDK7_CDK7_ST	Q15797	SMAD1	P50613	CDK7	S195	G197V	197	Missense	proximal	2	no	25.333	25.525	EPSD	TCGA;ICGC;COSMIC	13.598	Up-regulation
CMGC_CDK_CDK7_CDK7_ST	Q15797	SMAD1	P50613	CDK7	S195	S190T	190	Missense	distal	-5	no	25.333	24.034	EPSD	TCGA;ICGC;COSMIC	13.598	Down-regulation
CMGC_CDK_CDK7_CDK7_ST	Q15797	SMAD1	P50613	CDK7	S214	D221G	221	Missense	distal	7	no	16.769	19.250	EPSD	TCGA;ICGC;COSMIC	13.598	Up-regulation
CMGC_CDK_CDK7_CDK7_ST	P06493	CDK1	P50613	CDK7	S46	R50W	50	Missense	distal	4	no	14.793	16.006	EPSD	TCGA;ICGC;COSMIC	13.598	Up-regulation
CMGC_CDK_CDK7_CDK7_ST	P06493	CDK1	P50613	CDK7	S53	E57V	57	Missense	distal	4	no	21.987	21.974	EPSD	TCGA;ICGC;COSMIC	13.598	Down-regulation
CMGC_CDK_CDK7_CDK7_ST	P06493	CDK1	P50613	CDK7	S53	R59C	59	Missense	distal	6	no	21.987	20.789	EPSD	TCGA;ICGC;COSMIC;GDSC	13.598	Down-regulation
CMGC_CDK_CDK7_CDK7_ST	P06493	CDK1	P50613	CDK7	S53	R50W	50	Missense	distal	-3	no	21.987	15.998	EPSD	TCGA;ICGC;COSMIC	13.598	Down-regulation
CMGC_CDK_CDK7_CDK7_ST	P06493	CDK1	P50613	CDK7	S208	D211G	211	Missense	distal	3	no	19.691	18.114	EPSD	TCGA;ICGC;COSMIC	13.598	Down-regulation
CMGC_CDK_CDK7_CDK7_ST	P06493	CDK1	P50613	CDK7	S208	L213P	213	Missense	distal	5	no	19.691	19.275	EPSD	TCGA;ICGC;COSMIC	13.598	Down-regulation
CMGC_CDK_CDK7_CDK7_ST	P06493	CDK1	P50613	CDK7	S265	D271E	271	Missense	distal	6	no	12.476	14.322	EPSD	TCGA;ICGC;COSMIC	13.598	Gain
CMGC_CDK_CDK7_CDK7_ST	Q9BYE7	PCGF6	P50613	CDK7	S30	P28S	28	Missense	proximal	-2	no	24.161	24.482	PhosphoSitePlus	TCGA;ICGC;COSMIC	13.598	Up-regulation
CMGC_CDK_CDK7_CDK7_ST	Q9BYE7	PCGF6	P50613	CDK7	S115	R121L	121	Missense	distal	6	no	14.289	13.790	EPSD	TCGA;ICGC;COSMIC	13.598	Down-regulation
CMGC_CDK_CDK7_CDK7_ST	Q9BYE7	PCGF6	P50613	CDK7	S115	S115A	115	Missense	central	0	yes	14.289	0.000	EPSD	TCGA;ICGC;COSMIC	13.598	Loss
CMGC_CDK_CDK7_CDK7_ST	Q9BYE7	PCGF6	P50613	CDK7	S115	R121C	121	Missense	distal	6	no	14.289	13.092	EPSD	TCGA;ICGC;COSMIC	13.598	Loss
CMGC_CDK_CDK7_CDK7_ST	Q9BYE7	PCGF6	P50613	CDK7	S115	E119D	119	Missense	distal	4	no	14.289	17.160	EPSD	TCGA;ICGC;COSMIC	13.598	Up-regulation
CMGC_CDK_CDK7_CDK7_ST	P13631	RARG	P50613	CDK7	S43	S43I	43	Missense	central	0	yes	21.011	0.000	EPSD	TCGA;ICGC;COSMIC	13.598	Loss
CMGC_CDK_CDK7_CDK7_ST	P13631	RARG	P50613	CDK7	S43	M41I	41	Missense	proximal	-2	no	21.011	21.388	EPSD	TCGA;ICGC;COSMIC	13.598	Up-regulation
CMGC_CDK_CDK7_CDK7_ST	P13631	RARG	P50613	CDK7	S43	P44L	44	Missense	proximal	1	no	21.011	13.540	EPSD	TCGA;ICGC;COSMIC	13.598	Loss
CMGC_CDK_CDK7_CDK7_ST	P13631	RARG	P50613	CDK7	S77	P82L	82	Missense	distal	5	no	24.662	25.078	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	13.598	Up-regulation
CMGC_CDK_CDK7_CDK7_ST	P13631	RARG	P50613	CDK7	S77	S77L	77	Missense	central	0	yes	24.662	0.000	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	13.598	Loss
CMGC_CDK_CDK7_CDK7_ST	P13631	RARG	P50613	CDK7	S77	P82A	82	Missense	distal	5	no	24.662	25.405	EPSD;PhosphoSitePlus	TCGA;COSMIC	13.598	Up-regulation
CMGC_CDK_CDK7_CDK7_ST	P13631	RARG	P50613	CDK7	S79	P82L	82	Missense	distal	3	no	25.233	24.224	PhosphoSitePlus;EPSD	TCGA;ICGC;COSMIC	13.598	Down-regulation
CMGC_CDK_CDK7_CDK7_ST	P13631	RARG	P50613	CDK7	S79	S77L	77	Missense	proximal	-2	no	25.233	25.128	PhosphoSitePlus;EPSD	TCGA;ICGC;COSMIC	13.598	Down-regulation
CMGC_CDK_CDK7_CDK7_ST	P13631	RARG	P50613	CDK7	S79	P82A	82	Missense	distal	3	no	25.233	24.239	PhosphoSitePlus;EPSD	TCGA;COSMIC	13.598	Down-regulation
CMGC_CDK_CDK7_CDK7_ST	Q9NYV4	CDK12	P50613	CDK7	T57	L55F	55	Missense	proximal	-2	no	17.245	16.748	EPSD	TCGA;ICGC;COSMIC	13.598	Down-regulation
CMGC_CDK_CDK7_CDK7_ST	Q9NYV4	CDK12	P50613	CDK7	T57	V56M	56	Missense	proximal	-1	no	17.245	17.467	EPSD	TCGA;ICGC;COSMIC	13.598	Up-regulation
CMGC_CDK_CDK7_CDK7_ST	Q9NYV4	CDK12	P50613	CDK7	S62	L55F	55	Missense	distal	-7	no	16.417	16.562	EPSD	TCGA;ICGC;COSMIC	13.598	Up-regulation
CMGC_CDK_CDK7_CDK7_ST	Q9NYV4	CDK12	P50613	CDK7	S62	V56M	56	Missense	distal	-6	no	16.417	16.302	EPSD	TCGA;ICGC;COSMIC	13.598	Down-regulation
CMGC_CDK_CDK7_CDK7_ST	Q9NYV4	CDK12	P50613	CDK7	T82	D75Y	75	Missense	distal	-7	no	13.919	15.337	EPSD	TCGA;ICGC;COSMIC	13.598	Up-regulation
CMGC_CDK_CDK7_CDK7_ST	Q9NYV4	CDK12	P50613	CDK7	T82	D86N	86	Missense	distal	4	no	13.919	12.212	EPSD	TCGA;ICGC;COSMIC	13.598	Loss
CMGC_CDK_CDK7_CDK7_ST	Q9NYV4	CDK12	P50613	CDK7	T82	T82I	82	Missense	central	0	yes	13.919	0.000	EPSD	TCGA;ICGC	13.598	Loss
CMGC_CDK_CDK7_CDK7_ST	Q9NYV4	CDK12	P50613	CDK7	T206	K211T	211	Missense	distal	5	no	19.298	18.775	EPSD	TCGA;ICGC	13.598	Down-regulation
CMGC_CDK_CDK7_CDK7_ST	Q9NYV4	CDK12	P50613	CDK7	T206	V213M	213	Missense	distal	7	no	19.298	21.287	EPSD	TCGA;ICGC;COSMIC	13.598	Up-regulation
CMGC_CDK_CDK7_CDK7_ST	Q9NYV4	CDK12	P50613	CDK7	S215	R221K	221	Missense	distal	6	no	24.898	23.795	EPSD	TCGA;ICGC;COSMIC	13.598	Down-regulation
CMGC_CDK_CDK7_CDK7_ST	Q9NYV4	CDK12	P50613	CDK7	S215	K211T	211	Missense	distal	-4	no	24.898	24.275	EPSD	TCGA;ICGC	13.598	Down-regulation
CMGC_CDK_CDK7_CDK7_ST	Q9NYV4	CDK12	P50613	CDK7	S215	V213M	213	Missense	proximal	-2	no	24.898	24.799	EPSD	TCGA;ICGC;COSMIC	13.598	Down-regulation
CMGC_CDK_CDK7_CDK7_ST	Q9NYV4	CDK12	P50613	CDK7	S222	R221K	221	Missense	proximal	-1	no	15.259	15.250	EPSD	TCGA;ICGC;COSMIC	13.598	Down-regulation
CMGC_CDK_CDK7_CDK7_ST	Q9NYV4	CDK12	P50613	CDK7	S228	R221K	221	Missense	distal	-7	no	13.383	15.011	EPSD	TCGA;ICGC;COSMIC	13.598	Gain
CMGC_CDK_CDK7_CDK7_ST	Q9NYV4	CDK12	P50613	CDK7	S287	S283L	283	Missense	distal	-4	no	23.902	24.130	EPSD	TCGA;ICGC;COSMIC	13.598	Up-regulation
CMGC_CDK_CDK7_CDK7_ST	Q9NYV4	CDK12	P50613	CDK7	S287	Q286K	286	Missense	proximal	-1	no	23.902	23.451	EPSD	TCGA;ICGC;COSMIC	13.598	Down-regulation
CMGC_CDK_CDK7_CDK7_ST	Q9NYV4	CDK12	P50613	CDK7	S287	A284V	284	Missense	distal	-3	no	23.902	20.892	EPSD	TCGA;ICGC;COSMIC	13.598	Down-regulation
CMGC_CDK_CDK7_CDK7_ST	Q9NYV4	CDK12	P50613	CDK7	S291	Q286K	286	Missense	distal	-5	no	16.900	17.005	EPSD	TCGA;ICGC;COSMIC	13.598	Up-regulation
CMGC_CDK_CDK7_CDK7_ST	Q9NYV4	CDK12	P50613	CDK7	S291	A284V	284	Missense	distal	-7	no	16.900	18.178	EPSD	TCGA;ICGC;COSMIC	13.598	Up-regulation
CMGC_CDK_CDK7_CDK7_ST	Q9NYV4	CDK12	P50613	CDK7	S291	Y295C	295	Missense	distal	4	no	16.900	18.191	EPSD	TCGA;ICGC;COSMIC	13.598	Up-regulation
CMGC_CDK_CDK7_CDK7_ST	Q9NYV4	CDK12	P50613	CDK7	S318	S323L	323	Missense	distal	5	no	13.695	12.726	EPSD	TCGA;ICGC;COSMIC	13.598	Loss
CMGC_CDK_CDK7_CDK7_ST	Q9NYV4	CDK12	P50613	CDK7	S318	R322L	322	Missense	distal	4	no	13.695	11.670	EPSD	TCGA;ICGC;COSMIC	13.598	Loss
CMGC_CDK_CDK7_CDK7_ST	Q9NYV4	CDK12	P50613	CDK7	S325	S323L	323	Missense	proximal	-2	no	15.666	15.561	EPSD	TCGA;ICGC;COSMIC	13.598	Down-regulation
CMGC_CDK_CDK7_CDK7_ST	Q9NYV4	CDK12	P50613	CDK7	S325	Y327C	327	Missense	proximal	2	no	15.666	14.527	EPSD	TCGA;ICGC;COSMIC	13.598	Down-regulation
CMGC_CDK_CDK7_CDK7_ST	Q9NYV4	CDK12	P50613	CDK7	S325	R322L	322	Missense	distal	-3	no	15.666	12.719	EPSD	TCGA;ICGC;COSMIC	13.598	Loss
CMGC_CDK_CDK7_CDK7_ST	Q9NYV4	CDK12	P50613	CDK7	S333	Y327C	327	Missense	distal	-6	no	13.774	13.466	EPSD	TCGA;ICGC;COSMIC	13.598	Loss
CMGC_CDK_CDK7_CDK7_ST	Q9NYV4	CDK12	P50613	CDK7	S334	Y327C	327	Missense	distal	-7	no	15.999	14.475	EPSD	TCGA;ICGC;COSMIC	13.598	Down-regulation
CMGC_CDK_CDK7_CDK7_ST	Q9NYV4	CDK12	P50613	CDK7	S343	R344W	344	Missense	proximal	1	no	13.822	12.434	EPSD	TCGA;ICGC;COSMIC	13.598	Loss
CMGC_CDK_CDK7_CDK7_ST	Q9NYV4	CDK12	P50613	CDK7	S345	R344W	344	Missense	proximal	-1	no	15.512	14.834	EPSD	TCGA;ICGC;COSMIC	13.598	Down-regulation
CMGC_CDK_CDK7_CDK7_ST	Q9NYV4	CDK12	P50613	CDK7	S345	S352A	352	Missense	distal	7	no	15.512	19.226	EPSD	TCGA;ICGC;COSMIC	13.598	Up-regulation
CMGC_CDK_CDK7_CDK7_ST	Q9NYV4	CDK12	P50613	CDK7	S349	R344W	344	Missense	distal	-5	no	15.490	13.591	EPSD	TCGA;ICGC;COSMIC	13.598	Loss
CMGC_CDK_CDK7_CDK7_ST	Q9NYV4	CDK12	P50613	CDK7	S349	S352A	352	Missense	distal	3	no	15.490	15.243	EPSD	TCGA;ICGC;COSMIC	13.598	Down-regulation
CMGC_CDK_CDK7_CDK7_ST	Q9NYV4	CDK12	P50613	CDK7	S349	M353I	353	Missense	distal	4	no	15.490	14.067	EPSD	TCGA;ICGC;COSMIC	13.598	Down-regulation
CMGC_CDK_CDK7_CDK7_ST	Q9NYV4	CDK12	P50613	CDK7	S681	G677C	677	Missense	distal	-4	no	13.627	12.815	EPSD	TCGA;ICGC;COSMIC	13.598	Loss
CMGC_CDK_CDK7_CDK7_ST	Q9NYV4	CDK12	P50613	CDK7	S681	G677D	677	Missense	distal	-4	no	13.627	13.324	EPSD	TCGA;ICGC;COSMIC	13.598	Loss
CMGC_CDK_CDK7_CDK7_ST	Q9NYV4	CDK12	P50613	CDK7	S838	E845D	845	Missense	distal	7	no	16.125	13.434	EPSD	TCGA;ICGC;COSMIC	13.598	Loss
CMGC_CDK_CDK7_CDK7_ST	Q9NYV4	CDK12	P50613	CDK7	S838	K837N	837	Missense	proximal	-1	no	16.125	16.605	EPSD	TCGA;ICGC;COSMIC	13.598	Up-regulation
CMGC_CDK_CDK7_CDK7_ST	Q9NYV4	CDK12	P50613	CDK7	S838	M840V	840	Missense	proximal	2	no	16.125	16.541	EPSD	TCGA;ICGC;COSMIC	13.598	Up-regulation
CMGC_CDK_CDK7_CDK7_ST	Q9NYV4	CDK12	P50613	CDK7	S838	S838L	838	Missense	central	0	yes	16.125	0.000	EPSD	TCGA;ICGC;COSMIC	13.598	Loss
CMGC_CDK_CDK7_CDK7_ST	Q9NYV4	CDK12	P50613	CDK7	S886	P891L	891	Missense	distal	5	no	14.165	14.581	EPSD	TCGA;ICGC;COSMIC	13.598	Up-regulation
CMGC_CDK_CDK7_CDK7_ST	Q9NYV4	CDK12	P50613	CDK7	S886	R890H	890	Missense	distal	4	no	14.165	12.120	EPSD	TCGA;ICGC;COSMIC	13.598	Loss
CMGC_CDK_CDK7_CDK7_ST	Q9NYV4	CDK12	P50613	CDK7	S886	T893R	893	Missense	distal	7	no	14.165	16.406	EPSD	TCGA;ICGC;COSMIC	13.598	Up-regulation
CMGC_CDK_CDK7_CDK7_ST	Q9NYV4	CDK12	P50613	CDK7	S886	S889C	889	Missense	distal	3	no	14.165	14.660	EPSD	TCGA;ICGC;COSMIC	13.598	Up-regulation
CMGC_CDK_CDK7_CDK7_ST	Q9NYV4	CDK12	P50613	CDK7	S886	R882W	882	Missense	distal	-4	no	14.165	15.109	EPSD	TCGA;ICGC;COSMIC	13.598	Up-regulation
CMGC_CDK_CDK7_CDK7_ST	Q9NYV4	CDK12	P50613	CDK7	S886	R882Q	882	Missense	distal	-4	no	14.165	14.130	EPSD	TCGA;ICGC;COSMIC	13.598	Down-regulation
CMGC_CDK_CDK7_CDK7_ST	Q9NYV4	CDK12	P50613	CDK7	T893	P891L	891	Missense	proximal	-2	no	23.282	23.498	PhosphoSitePlus	TCGA;ICGC;COSMIC	13.598	Up-regulation
CMGC_CDK_CDK7_CDK7_ST	Q9NYV4	CDK12	P50613	CDK7	T893	R890H	890	Missense	distal	-3	no	23.282	18.968	PhosphoSitePlus	TCGA;ICGC;COSMIC	13.598	Down-regulation
CMGC_CDK_CDK7_CDK7_ST	Q9NYV4	CDK12	P50613	CDK7	T893	T893R	893	Missense	central	0	yes	23.282	0.000	PhosphoSitePlus	TCGA;ICGC;COSMIC	13.598	Loss
CMGC_CDK_CDK7_CDK7_ST	Q9NYV4	CDK12	P50613	CDK7	T893	S889C	889	Missense	distal	-4	no	23.282	23.382	PhosphoSitePlus	TCGA;ICGC;COSMIC	13.598	Up-regulation
CMGC_CDK_CDK7_CDK7_ST	Q9NYV4	CDK12	P50613	CDK7	S949	R950G	950	Missense	proximal	1	no	14.633	9.610	EPSD	TCGA;ICGC;COSMIC	13.598	Loss
CMGC_CDK_CDK7_CDK7_ST	Q9NYV4	CDK12	P50613	CDK7	S949	P955H	955	Missense	distal	6	no	14.633	14.905	EPSD	TCGA;ICGC;COSMIC	13.598	Up-regulation
CMGC_CDK_CDK7_CDK7_ST	Q9NYV4	CDK12	P50613	CDK7	S954	R950G	950	Missense	distal	-4	no	18.266	19.031	EPSD	TCGA;ICGC;COSMIC	13.598	Up-regulation
CMGC_CDK_CDK7_CDK7_ST	Q9NYV4	CDK12	P50613	CDK7	S954	P961S	961	Missense	distal	7	no	18.266	13.340	EPSD	TCGA;ICGC;COSMIC	13.598	Loss
CMGC_CDK_CDK7_CDK7_ST	Q9NYV4	CDK12	P50613	CDK7	S954	P955H	955	Missense	proximal	1	no	18.266	6.829	EPSD	TCGA;ICGC;COSMIC	13.598	Loss
CMGC_CDK_CDK7_CDK7_ST	Q9NYV4	CDK12	P50613	CDK7	S1006	R1008W	1008	Missense	proximal	2	no	12.672	14.240	EPSD	TCGA;ICGC;COSMIC;GDSC	13.598	Gain
CMGC_CDK_CDK7_CDK7_ST	Q9NYV4	CDK12	P50613	CDK7	S1063	E1069Q	1069	Missense	distal	6	no	14.709	14.042	EPSD	TCGA;ICGC;COSMIC	13.598	Down-regulation
CMGC_CDK_CDK7_CDK7_ST	Q9NYV4	CDK12	P50613	CDK7	S1063	S1066Y	1066	Missense	distal	3	no	14.709	15.380	EPSD	TCGA;ICGC;COSMIC	13.598	Up-regulation
CMGC_CDK_CDK7_CDK7_ST	Q9NYV4	CDK12	P50613	CDK7	S1063	S1066P	1066	Missense	distal	3	no	14.709	15.456	EPSD	TCGA;ICGC;COSMIC	13.598	Up-regulation
CMGC_CDK_CDK7_CDK7_ST	Q9NYV4	CDK12	P50613	CDK7	S1063	R1067Q	1067	Missense	distal	4	no	14.709	15.355	EPSD	TCGA;ICGC;COSMIC	13.598	Up-regulation
CMGC_CDK_CDK7_CDK7_ST	Q9NYV4	CDK12	P50613	CDK7	S1063	P1060L	1060	Missense	distal	-3	no	14.709	14.749	EPSD	TCGA;ICGC;COSMIC	13.598	Up-regulation
CMGC_CDK_CDK7_CDK7_ST	Q9NYV4	CDK12	P50613	CDK7	S1063	E1059D	1059	Missense	distal	-4	no	14.709	15.313	EPSD	TCGA;ICGC;COSMIC	13.598	Up-regulation
CMGC_CDK_CDK7_CDK7_ST	Q9NYV4	CDK12	P50613	CDK7	S1083	Q1088L	1088	Missense	distal	5	no	16.701	16.244	EPSD	TCGA;ICGC;COSMIC	13.598	Down-regulation
CMGC_CDK_CDK7_CDK7_ST	Q9NYV4	CDK12	P50613	CDK7	S1365	V1367I	1367	Missense	proximal	2	no	14.432	14.876	EPSD	TCGA;ICGC;COSMIC	13.598	Up-regulation
CMGC_CDK_CDK7_CDK7_ST	Q9NYV4	CDK12	P50613	CDK7	S1365	V1367L	1367	Missense	proximal	2	no	14.432	13.776	EPSD	TCGA;ICGC;COSMIC	13.598	Down-regulation
CMGC_CDK_CDK7_CDK7_ST	Q9NYV4	CDK12	P50613	CDK7	S1365	L1362F	1362	Missense	distal	-3	no	14.432	12.954	EPSD	TCGA;ICGC;COSMIC	13.598	Loss
CMGC_CDK_CDK7_CDK7_ST	P10275	AR	P50613	CDK7	S258	R264W	264	Missense	distal	6	no	23.761	21.288	EPSD	TCGA;ICGC;COSMIC	13.598	Down-regulation
CMGC_CDK_CDK7_CDK7_ST	P10275	AR	P50613	CDK7	S258	A253V	253	Missense	distal	-5	no	23.761	22.478	EPSD	TCGA;ICGC;COSMIC	13.598	Down-regulation
CMGC_CDK_CDK7_CDK7_ST	P10275	AR	P50613	CDK7	S310	E308K	308	Missense	proximal	-2	no	14.097	14.227	EPSD	TCGA;COSMIC	13.598	Up-regulation
CMGC_CDK_CDK7_CDK7_ST	P10275	AR	P50613	CDK7	S310	Y316H	316	Missense	distal	6	no	14.097	14.372	EPSD	TCGA;ICGC	13.598	Up-regulation
CMGC_CDK_CDK7_CDK7_ST	P10275	AR	P50613	CDK7	S516	P513S	513	Missense	distal	-3	no	26.004	25.595	PhosphoSitePlus	TCGA;ICGC;COSMIC	13.598	Down-regulation
CMGC_CDK_CDK7_CDK7_ST	P10275	AR	P50613	CDK7	S651	E645K	645	Missense	distal	-6	no	14.748	14.454	EPSD	TCGA;ICGC;COSMIC	13.598	Down-regulation
CMGC_CDK_CDK7_CDK7_ST	P10275	AR	P50613	CDK7	T657	V662L	662	Missense	distal	5	no	12.184	13.900	EPSD	TCGA;ICGC;COSMIC	13.598	Gain
CMGC_CDK_CDK7_CDK7_ST	Q13285	NR5A1	P50613	CDK7	S203	P210L	210	Missense	distal	7	no	44.824	40.153	PhosphoSitePlus	TCGA;ICGC;COSMIC	13.598	Down-regulation
AGC_NDR_NDR_STK38_ST	P46937	YAP1	Q15208	STK38	S61	S61W	61	Missense	central	0	yes	2.151	0.000	PhosphoSitePlus;EPSD	TCGA;ICGC;COSMIC	0.133	Loss
AGC_NDR_NDR_STK38_ST	P46937	YAP1	Q15208	STK38	T63	S61W	61	Missense	proximal	-2	no	0.151	0.147	EPSD	TCGA;ICGC;COSMIC	0.133	Down-regulation
AGC_NDR_NDR_STK38_ST	P46937	YAP1	Q15208	STK38	S94	F95C	95	Missense	proximal	1	no	0.214	0.213	EPSD	TCGA;ICGC	0.133	Down-regulation
AGC_NDR_NDR_STK38_ST	P46937	YAP1	Q15208	STK38	S109	R106Q	106	Missense	distal	-3	no	2.160	1.642	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC;CCLE	0.133	Down-regulation
AGC_NDR_NDR_STK38_ST	P46937	YAP1	Q15208	STK38	S109	S109N	109	Missense	central	0	yes	2.160	0.000	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	0.133	Loss
AGC_NDR_NDR_STK38_ST	P46937	YAP1	Q15208	STK38	S127	Q121H	121	Missense	distal	-6	no	2.198	2.203	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	0.133	Up-regulation
AGC_NDR_NDR_STK38_ST	P46937	YAP1	Q15208	STK38	S127	R124P	124	Missense	distal	-3	no	2.198	1.672	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	0.133	Down-regulation
AGC_NDR_NDR_STK38_ST	P46937	YAP1	Q15208	STK38	S127	R124Q	124	Missense	distal	-3	no	2.198	1.681	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	0.133	Down-regulation
AGC_NDR_NDR_STK38_ST	P46937	YAP1	Q15208	STK38	S131	G135E	135	Missense	distal	4	no	1.533	1.534	EPSD	TCGA;ICGC;COSMIC	0.133	Up-regulation
AGC_NDR_NDR_STK38_ST	P46937	YAP1	Q15208	STK38	S131	P129S	129	Missense	proximal	-2	no	1.533	1.535	EPSD	TCGA;ICGC;COSMIC	0.133	Up-regulation
AGC_NDR_NDR_STK38_ST	P46937	YAP1	Q15208	STK38	S131	S138F	138	Missense	distal	7	no	1.533	1.534	EPSD	TCGA;ICGC;COSMIC	0.133	Up-regulation
AGC_NDR_NDR_STK38_ST	P46937	YAP1	Q15208	STK38	S131	R124P	124	Missense	distal	-7	no	1.533	1.536	EPSD	TCGA;ICGC;COSMIC	0.133	Up-regulation
AGC_NDR_NDR_STK38_ST	P46937	YAP1	Q15208	STK38	S131	R124Q	124	Missense	distal	-7	no	1.533	1.536	EPSD	TCGA;ICGC;COSMIC	0.133	Up-regulation
AGC_NDR_NDR_STK38_ST	P46937	YAP1	Q15208	STK38	S163	Q158H	158	Missense	distal	-5	no	-0.054	1.688	EPSD	TCGA;ICGC;COSMIC	0.133	Gain
AGC_NDR_NDR_STK38_ST	P46937	YAP1	Q15208	STK38	S164	Q158H	158	Missense	distal	-6	no	2.147	2.151	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	0.133	Up-regulation
AGC_NDR_NDR_STK38_ST	P46937	YAP1	Q15208	STK38	S336	I333N	333	Missense	distal	-3	no	0.177	0.076	EPSD	TCGA;ICGC;COSMIC	0.133	Loss
AGC_NDR_NDR_STK38_ST	P46937	YAP1	Q15208	STK38	S336	N339H	339	Missense	distal	3	no	0.177	0.172	EPSD	TCGA;ICGC;COSMIC	0.133	Down-regulation
AGC_NDR_NDR_STK38_ST	Q15208	STK38	Q15208	STK38	T74	S67L	67	Missense	distal	-7	no	2.121	2.120	EPSD	TCGA;ICGC;COSMIC	0.133	Down-regulation
AGC_NDR_NDR_STK38_ST	Q15208	STK38	Q15208	STK38	S252	H251Y	251	Missense	proximal	-1	no	0.229	0.214	EPSD	TCGA;ICGC;COSMIC	0.133	Down-regulation
AGC_NDR_NDR_STK38_ST	Q96QF0	RAB3IP	Q15208	STK38	T46	Q47E	47	Missense	proximal	1	no	0.134	0.132	EPSD	TCGA;COSMIC	0.133	Loss
AGC_NDR_NDR_STK38_ST	Q96QF0	RAB3IP	Q15208	STK38	T46	S44L	44	Missense	proximal	-2	no	0.134	0.127	EPSD	TCGA;ICGC;COSMIC	0.133	Loss
AGC_NDR_NDR_STK38_ST	Q96QF0	RAB3IP	Q15208	STK38	S163	R160H	160	Missense	distal	-3	no	0.358	-0.077	EPSD	TCGA;COSMIC;GDSC	0.133	Loss
AGC_NDR_NDR_STK38_ST	Q96QF0	RAB3IP	Q15208	STK38	S163	S163I	163	Missense	central	0	yes	0.358	0.000	EPSD	TCGA;ICGC;COSMIC	0.133	Loss
AGC_NDR_NDR_STK38_ST	Q96QF0	RAB3IP	Q15208	STK38	S163	R160C	160	Missense	distal	-3	no	0.358	-0.136	EPSD	TCGA;ICGC;COSMIC	0.133	Loss
AGC_NDR_NDR_STK38_ST	Q96QF0	RAB3IP	Q15208	STK38	S163	R162Q	162	Missense	proximal	-1	no	0.358	0.355	EPSD	TCGA;ICGC;COSMIC	0.133	Down-regulation
AGC_NDR_NDR_STK38_ST	Q96QF0	RAB3IP	Q15208	STK38	S165	R160H	160	Missense	distal	-5	no	0.642	2.112	EPSD	TCGA;COSMIC;GDSC	0.133	Up-regulation
AGC_NDR_NDR_STK38_ST	Q96QF0	RAB3IP	Q15208	STK38	S165	S163I	163	Missense	proximal	-2	no	0.642	0.637	EPSD	TCGA;ICGC;COSMIC	0.133	Down-regulation
AGC_NDR_NDR_STK38_ST	Q96QF0	RAB3IP	Q15208	STK38	S165	R160C	160	Missense	distal	-5	no	0.642	0.464	EPSD	TCGA;ICGC;COSMIC	0.133	Down-regulation
AGC_NDR_NDR_STK38_ST	Q96QF0	RAB3IP	Q15208	STK38	S165	R162Q	162	Missense	distal	-3	no	0.642	0.124	EPSD	TCGA;ICGC;COSMIC	0.133	Loss
AGC_NDR_NDR_STK38_ST	Q96QF0	RAB3IP	Q15208	STK38	S288	G295D	295	Missense	distal	7	no	2.190	2.189	PhosphoSitePlus	TCGA;COSMIC;GDSC	0.133	Down-regulation
AGC_NDR_NDR_STK38_ST	Q96QF0	RAB3IP	Q15208	STK38	S288	R285I	285	Missense	distal	-3	no	2.190	1.768	PhosphoSitePlus	TCGA;COSMIC	0.133	Down-regulation
AGC_NDR_NDR_STK38_ST	Q96QF0	RAB3IP	Q15208	STK38	S290	R285I	285	Missense	distal	-5	no	0.174	-0.039	EPSD	TCGA;COSMIC	0.133	Loss
AGC_NDR_NDR_STK38_ST	Q02241	KIF23	Q15208	STK38	T8	R10W	10	Missense	proximal	2	no	0.263	0.267	EPSD	TCGA;ICGC;COSMIC	0.133	Up-regulation
AGC_NDR_NDR_STK38_ST	Q02241	KIF23	Q15208	STK38	T13	R10W	10	Missense	distal	-3	no	0.347	-0.141	EPSD	TCGA;ICGC;COSMIC	0.133	Loss
AGC_NDR_NDR_STK38_ST	Q02241	KIF23	Q15208	STK38	T20	G17R	17	Missense	distal	-3	no	-0.180	0.360	EPSD	TCGA;ICGC;COSMIC	0.133	Gain
AGC_NDR_NDR_STK38_ST	Q02241	KIF23	Q15208	STK38	T56	Q53R	53	Missense	distal	-3	no	-0.180	0.338	EPSD	TCGA;ICGC;COSMIC	0.133	Gain
AGC_NDR_NDR_STK38_ST	Q02241	KIF23	Q15208	STK38	S125	M122V	122	Missense	distal	-3	no	1.621	1.598	EPSD	TCGA;ICGC;COSMIC	0.133	Down-regulation
AGC_NDR_NDR_STK38_ST	Q02241	KIF23	Q15208	STK38	T292	S298F	298	Missense	distal	6	no	0.227	0.228	EPSD	TCGA;COSMIC	0.133	Up-regulation
AGC_NDR_NDR_STK38_ST	Q02241	KIF23	Q15208	STK38	T292	L294F	294	Missense	proximal	2	no	0.227	0.228	EPSD	TCGA;COSMIC	0.133	Up-regulation
AGC_NDR_NDR_STK38_ST	Q02241	KIF23	Q15208	STK38	T292	R288H	288	Missense	distal	-4	no	0.227	0.228	EPSD	TCGA;COSMIC	0.133	Up-regulation
AGC_NDR_NDR_STK38_ST	Q02241	KIF23	Q15208	STK38	T292	R288C	288	Missense	distal	-4	no	0.227	0.228	EPSD	TCGA;COSMIC	0.133	Up-regulation
AGC_NDR_NDR_STK38_ST	Q02241	KIF23	Q15208	STK38	S298	S298F	298	Missense	central	0	yes	1.565	0.000	EPSD	TCGA;COSMIC	0.133	Loss
AGC_NDR_NDR_STK38_ST	Q02241	KIF23	Q15208	STK38	S299	S298F	298	Missense	proximal	-1	no	0.300	0.303	EPSD	TCGA;COSMIC	0.133	Up-regulation
AGC_NDR_NDR_STK38_ST	Q02241	KIF23	Q15208	STK38	S299	L294F	294	Missense	distal	-5	no	0.300	0.399	EPSD	TCGA;COSMIC	0.133	Up-regulation
AGC_NDR_NDR_STK38_ST	Q02241	KIF23	Q15208	STK38	S303	S298F	298	Missense	distal	-5	no	0.260	0.438	EPSD	TCGA;COSMIC	0.133	Up-regulation
AGC_NDR_NDR_STK38_ST	Q02241	KIF23	Q15208	STK38	S605	F604L	604	Missense	proximal	-1	no	0.331	0.329	EPSD	TCGA;COSMIC	0.133	Down-regulation
AGC_NDR_NDR_STK38_ST	Q02241	KIF23	Q15208	STK38	S605	R608H	608	Missense	distal	3	no	0.331	0.328	EPSD	TCGA;COSMIC;GDSC;CCLE	0.133	Down-regulation
AGC_NDR_NDR_STK38_ST	Q02241	KIF23	Q15208	STK38	S684	P685S	685	Missense	proximal	1	no	0.350	0.349	EPSD	TCGA;COSMIC	0.133	Down-regulation
AGC_NDR_NDR_STK38_ST	Q02241	KIF23	Q15208	STK38	S716	C717Y	717	Missense	proximal	1	no	2.167	2.168	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	0.133	Up-regulation
AGC_NDR_NDR_STK38_ST	Q02241	KIF23	Q15208	STK38	S716	R713H	713	Missense	distal	-3	no	2.167	1.732	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	0.133	Down-regulation
AGC_NDR_NDR_STK38_ST	Q02241	KIF23	Q15208	STK38	S718	R713H	713	Missense	distal	-5	no	0.148	1.618	EPSD	TCGA;ICGC;COSMIC	0.133	Up-regulation
AGC_NDR_NDR_STK38_ST	Q02241	KIF23	Q15208	STK38	S814	D817N	817	Missense	distal	3	no	2.152	2.153	PhosphoSitePlus;EPSD	TCGA;COSMIC	0.133	Up-regulation
AGC_NDR_NDR_STK38_ST	Q02241	KIF23	Q15208	STK38	S814	R813H	813	Missense	proximal	-1	no	2.152	2.164	PhosphoSitePlus;EPSD	TCGA;COSMIC	0.133	Up-regulation
AGC_NDR_NDR_STK38_ST	Q02241	KIF23	Q15208	STK38	S814	S814F	814	Missense	central	0	yes	2.152	0.000	PhosphoSitePlus;EPSD	TCGA;COSMIC	0.133	Loss
AGC_NDR_NDR_STK38_ST	Q02241	KIF23	Q15208	STK38	S943	E938K	938	Missense	distal	-5	no	0.377	0.409	EPSD	TCGA;COSMIC	0.133	Up-regulation
AGC_NDR_NDR_STK38_ST	Q02241	KIF23	Q15208	STK38	S943	R940T	940	Missense	distal	-3	no	0.377	-0.150	EPSD	TCGA;COSMIC	0.133	Loss
AGC_NDR_NDR_STK38_ST	Q02241	KIF23	Q15208	STK38	S943	A941V	941	Missense	proximal	-2	no	0.377	0.372	EPSD	TCGA;COSMIC	0.133	Down-regulation
CAMK_CAMKL_AMPK_PRKAA1_ST	Q9Y478	PRKAB1	Q13131	PRKAA1	S24	G27D	27	Missense	distal	3	no	60.885	60.423	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	56.683	Down-regulation
CAMK_CAMKL_AMPK_PRKAA1_ST	Q9Y478	PRKAB1	Q13131	PRKAA1	S25	G27D	27	Missense	proximal	2	no	60.119	61.271	EPSD	TCGA;ICGC;COSMIC	56.683	Up-regulation
CAMK_CAMKL_AMPK_PRKAA1_ST	Q9Y478	PRKAB1	Q13131	PRKAA1	T80	R83P	83	Missense	distal	3	no	58.942	57.355	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	56.683	Down-regulation
CAMK_CAMKL_AMPK_PRKAA1_ST	Q9Y478	PRKAB1	Q13131	PRKAA1	T80	G87C	87	Missense	distal	7	no	58.942	58.440	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	56.683	Down-regulation
CAMK_CAMKL_AMPK_PRKAA1_ST	Q9Y478	PRKAB1	Q13131	PRKAA1	T80	G87D	87	Missense	distal	7	no	58.942	57.773	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	56.683	Down-regulation
CAMK_CAMKL_AMPK_PRKAA1_ST	Q9Y478	PRKAB1	Q13131	PRKAA1	S96	W100R	100	Missense	distal	4	no	58.453	55.202	EPSD	TCGA;ICGC;COSMIC	56.683	Loss
CAMK_CAMKL_AMPK_PRKAA1_ST	Q9Y478	PRKAB1	Q13131	PRKAA1	S101	W100R	100	Missense	proximal	-1	no	56.896	56.809	EPSD	TCGA;ICGC;COSMIC	56.683	Down-regulation
CAMK_CAMKL_AMPK_PRKAA1_ST	Q9Y478	PRKAB1	Q13131	PRKAA1	S108	N110S	110	Missense	proximal	2	no	64.453	64.697	PhosphoSitePlus;EPSD	TCGA;ICGC;COSMIC	56.683	Up-regulation
CAMK_CAMKL_AMPK_PRKAA1_ST	Q9Y478	PRKAB1	Q13131	PRKAA1	T158	D159G	159	Missense	proximal	1	no	62.227	63.653	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	56.683	Up-regulation
CAMK_CAMKL_AMPK_PRKAA1_ST	Q9Y478	PRKAB1	Q13131	PRKAA1	S177	S181N	181	Missense	distal	4	no	61.246	59.775	EPSD;PhosphoSitePlus	TCGA	56.683	Down-regulation
CAMK_CAMKL_AMPK_PRKAA1_ST	Q9Y478	PRKAB1	Q13131	PRKAA1	S182	S181N	181	Missense	proximal	-1	no	57.293	57.254	EPSD	TCGA	56.683	Down-regulation
CAMK_CAMKL_AMPK_PRKAA1_ST	Q9Y478	PRKAB1	Q13131	PRKAA1	S182	G185R	185	Missense	distal	3	no	57.293	55.441	EPSD	TCGA;ICGC;COSMIC	56.683	Loss
CAMK_CAMKL_AMPK_PRKAA1_ST	P10636	MAPT	Q13131	PRKAA1	S46	G42C	42	Missense	distal	-4	no	53.759	61.677	EPSD	TCGA;ICGC;COSMIC	56.683	Gain
CAMK_CAMKL_AMPK_PRKAA1_ST	P10636	MAPT	Q13131	PRKAA1	T63	A66S	66	Missense	distal	3	no	54.410	58.389	EPSD	TCGA;ICGC;COSMIC	56.683	Gain
CAMK_CAMKL_AMPK_PRKAA1_ST	P10636	MAPT	Q13131	PRKAA1	S171	R168H	168	Missense	distal	-3	no	59.279	51.423	EPSD	TCGA;ICGC;COSMIC	56.683	Loss
CAMK_CAMKL_AMPK_PRKAA1_ST	P10636	MAPT	Q13131	PRKAA1	S171	R168C	168	Missense	distal	-3	no	59.279	45.132	EPSD	TCGA;ICGC;COSMIC	56.683	Loss
CAMK_CAMKL_AMPK_PRKAA1_ST	P10636	MAPT	Q13131	PRKAA1	S214	P212L	212	Missense	proximal	-2	no	71.752	68.777	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	56.683	Down-regulation
CAMK_CAMKL_AMPK_PRKAA1_ST	P10636	MAPT	Q13131	PRKAA1	S214	E220K	220	Missense	distal	6	no	71.752	71.524	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	56.683	Down-regulation
CAMK_CAMKL_AMPK_PRKAA1_ST	P10636	MAPT	Q13131	PRKAA1	S388	G387R	387	Missense	proximal	-1	no	58.314	58.275	EPSD	TCGA;COSMIC	56.683	Down-regulation
CAMK_CAMKL_AMPK_PRKAA1_ST	P10636	MAPT	Q13131	PRKAA1	S451	E456K	456	Missense	distal	5	no	58.331	58.353	EPSD	TCGA;ICGC;COSMIC	56.683	Up-regulation
CAMK_CAMKL_AMPK_PRKAA1_ST	P10636	MAPT	Q13131	PRKAA1	S451	S452C	452	Missense	proximal	1	no	58.331	57.669	EPSD	TCGA;ICGC;COSMIC	56.683	Down-regulation
CAMK_CAMKL_AMPK_PRKAA1_ST	P10636	MAPT	Q13131	PRKAA1	S451	S444F	444	Missense	distal	-7	no	58.331	55.739	EPSD	TCGA;ICGC	56.683	Loss
CAMK_CAMKL_AMPK_PRKAA1_ST	P10636	MAPT	Q13131	PRKAA1	S451	S452Y	452	Missense	proximal	1	no	58.331	60.648	EPSD	TCGA;ICGC;COSMIC	56.683	Up-regulation
CAMK_CAMKL_AMPK_PRKAA1_ST	P05091	ALDH2	Q13131	PRKAA1	T429	E432K	432	Missense	distal	3	no	56.341	58.065	EPSD	TCGA;COSMIC	56.683	Gain
CAMK_CAMKL_AMPK_PRKAA1_ST	Q7Z3C6	ATG9A	Q13131	PRKAA1	S654	L652V	652	Missense	proximal	-2	no	62.685	65.119	EPSD	TCGA;COSMIC	56.683	Up-regulation
CAMK_CAMKL_AMPK_PRKAA1_ST	Q7Z3C6	ATG9A	Q13131	PRKAA1	S654	A649V	649	Missense	distal	-5	no	62.685	61.492	EPSD	TCGA;COSMIC	56.683	Down-regulation
CAMK_CAMKL_AMPK_PRKAA1_ST	Q7Z3C6	ATG9A	Q13131	PRKAA1	S683	A682G	682	Missense	proximal	-1	no	61.978	61.962	EPSD	TCGA;COSMIC	56.683	Down-regulation
CAMK_CAMKL_AMPK_PRKAA1_ST	Q7Z3C6	ATG9A	Q13131	PRKAA1	S738	A742T	742	Missense	distal	4	no	63.700	61.131	EPSD	TCGA;COSMIC	56.683	Down-regulation
CAMK_CAMKL_AMPK_PRKAA1_ST	Q7Z3C6	ATG9A	Q13131	PRKAA1	S738	R733W	733	Missense	distal	-5	no	63.700	58.506	EPSD	TCGA;COSMIC	56.683	Down-regulation
CAMK_CAMKL_AMPK_PRKAA1_ST	Q7Z3C6	ATG9A	Q13131	PRKAA1	S761	P767L	767	Missense	distal	6	no	63.081	63.229	PhosphoSitePlus	TCGA;COSMIC	56.683	Up-regulation
CAMK_CAMKL_AMPK_PRKAA1_ST	Q7Z3C6	ATG9A	Q13131	PRKAA1	S761	S755Y	755	Missense	distal	-6	no	63.081	60.583	PhosphoSitePlus	TCGA	56.683	Down-regulation
CAMK_CAMKL_AMPK_PRKAA1_ST	Q7Z3C6	ATG9A	Q13131	PRKAA1	S761	R758H	758	Missense	distal	-3	no	63.081	55.224	PhosphoSitePlus	TCGA;COSMIC	56.683	Loss
CAMK_CAMKL_AMPK_PRKAA1_ST	Q7Z3C6	ATG9A	Q13131	PRKAA1	S799	S799C	799	Missense	central	0	yes	66.385	0.000	EPSD	TCGA;COSMIC	56.683	Loss
CAMK_CAMKL_AMPK_PRKAA1_ST	Q7Z3C6	ATG9A	Q13131	PRKAA1	S799	R803Q	803	Missense	distal	4	no	66.385	62.301	EPSD	TCGA;COSMIC	56.683	Down-regulation
CAMK_CAMKL_AMPK_PRKAA1_ST	Q7Z3C6	ATG9A	Q13131	PRKAA1	S828	V823M	823	Missense	distal	-5	no	56.617	61.314	EPSD	TCGA;COSMIC	56.683	Gain
CAMK_CAMKL_AMPK_PRKAA1_ST	Q7Z3C6	ATG9A	Q13131	PRKAA1	S828	E825K	825	Missense	distal	-3	no	56.617	60.458	EPSD	TCGA;COSMIC	56.683	Gain
CAMK_CAMKL_AMPK_PRKAA1_ST	Q7Z628	NET1	Q13131	PRKAA1	S78	S78G	78	Missense	central	0	yes	59.453	0.000	EPSD	TCGA;ICGC;COSMIC	56.683	Loss
CAMK_CAMKL_AMPK_PRKAA1_ST	Q7Z628	NET1	Q13131	PRKAA1	S80	S78G	78	Missense	proximal	-2	no	62.041	58.736	EPSD	TCGA;ICGC;COSMIC	56.683	Down-regulation
CAMK_CAMKL_AMPK_PRKAA1_ST	Q7Z628	NET1	Q13131	PRKAA1	S100	T99M	99	Missense	proximal	-1	no	72.161	72.236	PhosphoSitePlus	TCGA;ICGC;COSMIC	56.683	Up-regulation
CAMK_CAMKL_AMPK_PRKAA1_ST	Q7Z628	NET1	Q13131	PRKAA1	S100	S106F	106	Missense	distal	6	no	72.161	72.427	PhosphoSitePlus	TCGA;ICGC;COSMIC	56.683	Up-regulation
CAMK_CAMKL_AMPK_PRKAA1_ST	Q7Z628	NET1	Q13131	PRKAA1	S100	R97C	97	Missense	distal	-3	no	72.161	58.014	PhosphoSitePlus	TCGA;ICGC;COSMIC	56.683	Down-regulation
CAMK_CAMKL_AMPK_PRKAA1_ST	Q7Z628	NET1	Q13131	PRKAA1	S100	N103D	103	Missense	distal	3	no	72.161	70.908	PhosphoSitePlus	TCGA;ICGC;COSMIC	56.683	Down-regulation
CAMK_CAMKL_AMPK_PRKAA1_ST	Q7Z628	NET1	Q13131	PRKAA1	T119	A112T	112	Missense	distal	-7	no	55.992	56.841	EPSD	TCGA;ICGC	56.683	Gain
CAMK_CAMKL_AMPK_PRKAA1_ST	Q7Z628	NET1	Q13131	PRKAA1	S451	S451C	451	Missense	central	0	yes	58.017	0.000	EPSD	TCGA;ICGC	56.683	Loss
CAMK_CAMKL_AMPK_PRKAA1_ST	Q7Z628	NET1	Q13131	PRKAA1	S539	S539F	539	Missense	central	0	yes	63.855	0.000	EPSD	TCGA;ICGC;COSMIC	56.683	Loss
CAMK_CAMKL_AMPK_PRKAA1_ST	P07954	FH	Q13131	PRKAA1	T56	S49F	49	Missense	distal	-7	no	64.956	62.364	EPSD	TCGA;ICGC;COSMIC	56.683	Down-regulation
CAMK_CAMKL_AMPK_PRKAA1_ST	P07954	FH	Q13131	PRKAA1	S75	T76M	76	Missense	proximal	1	no	58.340	61.425	PhosphoSitePlus	TCGA;ICGC;COSMIC	56.683	Up-regulation
CAMK_CAMKL_AMPK_PRKAA1_ST	P07954	FH	Q13131	PRKAA1	S75	T72S	72	Missense	distal	-3	no	58.340	63.056	PhosphoSitePlus	TCGA;ICGC;COSMIC	56.683	Up-regulation
CAMK_CAMKL_AMPK_PRKAA1_ST	P07954	FH	Q13131	PRKAA1	S75	A70T	70	Missense	distal	-5	no	58.340	56.348	PhosphoSitePlus	TCGA;ICGC;COSMIC	56.683	Loss
CAMK_CAMKL_AMPK_PRKAA1_ST	Q8IY63	AMOTL1	Q13131	PRKAA1	S52	H49R	49	Missense	distal	-3	no	55.673	63.530	EPSD	TCGA;ICGC;COSMIC	56.683	Gain
CAMK_CAMKL_AMPK_PRKAA1_ST	Q8IY63	AMOTL1	Q13131	PRKAA1	S76	I82L	82	Missense	distal	6	no	62.687	63.142	EPSD	TCGA;ICGC;COSMIC	56.683	Up-regulation
CAMK_CAMKL_AMPK_PRKAA1_ST	Q8IY63	AMOTL1	Q13131	PRKAA1	S76	N73T	73	Missense	distal	-3	no	62.687	54.512	EPSD	TCGA;ICGC;COSMIC	56.683	Loss
CAMK_CAMKL_AMPK_PRKAA1_ST	Q8IY63	AMOTL1	Q13131	PRKAA1	S76	S76A	76	Missense	central	0	yes	62.687	0.000	EPSD	TCGA;ICGC;COSMIC	56.683	Loss
CAMK_CAMKL_AMPK_PRKAA1_ST	Q8IY63	AMOTL1	Q13131	PRKAA1	S76	P70S	70	Missense	distal	-6	no	62.687	62.337	EPSD	TCGA;ICGC	56.683	Down-regulation
CAMK_CAMKL_AMPK_PRKAA1_ST	Q8IY63	AMOTL1	Q13131	PRKAA1	S262	E263K	263	Missense	proximal	1	no	64.416	65.345	EPSD	TCGA;ICGC;COSMIC	56.683	Up-regulation
CAMK_CAMKL_AMPK_PRKAA1_ST	Q8IY63	AMOTL1	Q13131	PRKAA1	S262	S262I	262	Missense	central	0	yes	64.416	0.000	EPSD	TCGA;ICGC	56.683	Loss
CAMK_CAMKL_AMPK_PRKAA1_ST	Q8IY63	AMOTL1	Q13131	PRKAA1	S724	S729L	729	Missense	distal	5	no	58.458	58.490	EPSD	TCGA;ICGC	56.683	Up-regulation
CAMK_CAMKL_AMPK_PRKAA1_ST	Q8IY63	AMOTL1	Q13131	PRKAA1	S793	A798P	798	Missense	distal	5	no	58.596	58.589	PhosphoSitePlus	TCGA;ICGC;COSMIC	56.683	Down-regulation
CAMK_CAMKL_AMPK_PRKAA1_ST	Q8IY63	AMOTL1	Q13131	PRKAA1	S793	R789C	789	Missense	distal	-4	no	58.596	62.907	PhosphoSitePlus	TCGA;ICGC;COSMIC	56.683	Up-regulation
CAMK_CAMKL_AMPK_PRKAA1_ST	Q8IY63	AMOTL1	Q13131	PRKAA1	S793	P790T	790	Missense	distal	-3	no	58.596	53.345	PhosphoSitePlus	TCGA;ICGC;COSMIC	56.683	Loss
CAMK_CAMKL_AMPK_PRKAA1_ST	Q8IY63	AMOTL1	Q13131	PRKAA1	S793	P790L	790	Missense	distal	-3	no	58.596	57.489	PhosphoSitePlus	TCGA;ICGC;COSMIC	56.683	Down-regulation
CAMK_CAMKL_AMPK_PRKAA1_ST	Q8IY63	AMOTL1	Q13131	PRKAA1	S793	A800T	800	Missense	distal	7	no	58.596	58.222	PhosphoSitePlus	TCGA;ICGC;COSMIC	56.683	Down-regulation
CAMK_CAMKL_AMPK_PRKAA1_ST	Q8IY63	AMOTL1	Q13131	PRKAA1	S876	K873R	873	Missense	distal	-3	no	56.628	61.269	EPSD	TCGA;COSMIC	56.683	Gain
CAMK_CAMKL_AMPK_PRKAA1_ST	Q8IY63	AMOTL1	Q13131	PRKAA1	S876	Q878H	878	Missense	proximal	2	no	56.628	57.400	EPSD	TCGA;COSMIC	56.683	Gain
CAMK_CAMKL_AMPK_PRKAA1_ST	Q8IY63	AMOTL1	Q13131	PRKAA1	S889	E884K	884	Missense	distal	-5	no	65.605	62.958	EPSD	TCGA;COSMIC	56.683	Down-regulation
CAMK_CAMKL_AMPK_PRKAA1_ST	Q8IY63	AMOTL1	Q13131	PRKAA1	S889	A891T	891	Missense	proximal	2	no	65.605	66.052	EPSD	TCGA;COSMIC	56.683	Up-regulation
CAMK_CAMKL_AMPK_PRKAA1_ST	Q8IY63	AMOTL1	Q13131	PRKAA1	S889	S882N	882	Missense	distal	-7	no	65.605	64.514	EPSD	TCGA;COSMIC	56.683	Down-regulation
CAMK_CAMKL_AMPK_PRKAA1_ST	Q8IY63	AMOTL1	Q13131	PRKAA1	S889	A883T	883	Missense	distal	-6	no	65.605	65.402	EPSD	TCGA;COSMIC;GDSC;CCLE	56.683	Down-regulation
CAMK_CAMKL_AMPK_PRKAA1_ST	Q13131	PRKAA1	Q13131	PRKAA1	S65	S65N	65	Missense	central	0	yes	59.336	0.000	EPSD	TCGA;ICGC;COSMIC	56.683	Loss
CAMK_CAMKL_AMPK_PRKAA1_ST	Q13131	PRKAA1	Q13131	PRKAA1	S65	R60Q	60	Missense	distal	-5	no	59.336	53.654	EPSD	TCGA;ICGC;COSMIC;GDSC;CCLE	56.683	Loss
CAMK_CAMKL_AMPK_PRKAA1_ST	Q13131	PRKAA1	Q13131	PRKAA1	S65	G70E	70	Missense	distal	5	no	59.336	59.335	EPSD	TCGA;ICGC;COSMIC	56.683	Down-regulation
CAMK_CAMKL_AMPK_PRKAA1_ST	Q15036	SNX17	Q13131	PRKAA1	S312	T316A	316	Missense	distal	4	no	65.764	68.332	EPSD	TCGA;COSMIC	56.683	Up-regulation
CAMK_CAMKL_AMPK_PRKAA1_ST	Q15036	SNX17	Q13131	PRKAA1	S335	R339W	339	Missense	distal	4	no	58.513	61.764	EPSD	TCGA;COSMIC	56.683	Up-regulation
CAMK_CAMKL_AMPK_PRKAA1_ST	Q15036	SNX17	Q13131	PRKAA1	S388	K386N	386	Missense	proximal	-2	no	58.391	57.592	EPSD	TCGA	56.683	Down-regulation
CAMK_CAMKL_AMPK_PRKAA1_ST	Q15036	SNX17	Q13131	PRKAA1	S409	D408N	408	Missense	proximal	-1	no	61.606	61.566	EPSD	TCGA;COSMIC;CCLE	56.683	Down-regulation
CAMK_CAMKL_AMPK_PRKAA1_ST	Q15036	SNX17	Q13131	PRKAA1	S409	R406H	406	Missense	distal	-3	no	61.606	53.749	EPSD	TCGA;COSMIC	56.683	Loss
CAMK_CAMKL_AMPK_PRKAA1_ST	Q15036	SNX17	Q13131	PRKAA1	S409	P416S	416	Missense	distal	7	no	61.606	62.104	EPSD	TCGA	56.683	Up-regulation
CAMK_CAMKL_AMPK_PRKAA1_ST	Q15036	SNX17	Q13131	PRKAA1	S409	R406C	406	Missense	distal	-3	no	61.606	47.459	EPSD	TCGA;COSMIC	56.683	Loss
CAMK_CAMKL_AMPK_PRKAA1_ST	Q15036	SNX17	Q13131	PRKAA1	S409	P416L	416	Missense	distal	7	no	61.606	62.146	EPSD	TCGA	56.683	Up-regulation
CAMK_CAMKL_AMPK_PRKAA1_ST	Q15036	SNX17	Q13131	PRKAA1	T425	E420Q	420	Missense	distal	-5	no	57.049	51.809	EPSD	TCGA	56.683	Loss
CAMK_CAMKL_AMPK_PRKAA1_ST	Q15036	SNX17	Q13131	PRKAA1	T425	R426W	426	Missense	proximal	1	no	57.049	57.655	EPSD	TCGA;COSMIC	56.683	Up-regulation
CAMK_CAMKL_AMPK_PRKAA1_ST	Q15036	SNX17	Q13131	PRKAA1	T425	P422S	422	Missense	distal	-3	no	57.049	56.514	EPSD	TCGA;COSMIC	56.683	Loss
CAMK_CAMKL_AMPK_PRKAA1_ST	Q15036	SNX17	Q13131	PRKAA1	S428	R426W	426	Missense	proximal	-2	no	60.645	58.306	EPSD	TCGA;COSMIC	56.683	Down-regulation
CAMK_CAMKL_AMPK_PRKAA1_ST	Q15036	SNX17	Q13131	PRKAA1	S428	P422S	422	Missense	distal	-6	no	60.645	60.295	EPSD	TCGA;COSMIC	56.683	Down-regulation
CAMK_CAMKL_AMPK_PRKAA1_ST	Q9UQL6	HDAC5	Q13131	PRKAA1	S55	G52E	52	Missense	distal	-3	no	60.907	61.460	EPSD	TCGA;ICGC;COSMIC	56.683	Up-regulation
CAMK_CAMKL_AMPK_PRKAA1_ST	Q8NE86	MCU	Q13131	PRKAA1	T232	E229Q	229	Missense	distal	-3	no	56.370	56.907	EPSD	TCGA;COSMIC	56.683	Gain
CAMK_CAMKL_AMPK_PRKAA1_ST	Q8NE86	MCU	Q13131	PRKAA1	T233	E229Q	229	Missense	distal	-4	no	58.575	57.162	EPSD	TCGA;COSMIC	56.683	Down-regulation
CAMK_CAMKL_AMPK_PRKAA1_ST	Q8NE86	MCU	Q13131	PRKAA1	T233	K230R	230	Missense	distal	-3	no	58.575	63.217	EPSD	TCGA;COSMIC	56.683	Up-regulation
CAMK_CAMKL_AMPK_PRKAA1_ST	Q8NE86	MCU	Q13131	PRKAA1	T233	A228V	228	Missense	distal	-5	no	58.575	57.383	EPSD	TCGA;COSMIC	56.683	Down-regulation
CAMK_CAMKL_AMPK_PRKAA1_ST	Q8NE86	MCU	Q13131	PRKAA1	T233	R226K	226	Missense	distal	-7	no	58.575	60.179	EPSD	TCGA;COSMIC	56.683	Up-regulation
CAMK_CAMKL_AMPK_PRKAA1_ST	P04406	GAPDH	Q13131	PRKAA1	T19	G15R	15	Missense	distal	-4	no	53.117	56.724	EPSD	TCGA;ICGC;COSMIC	56.683	Gain
CAMK_CAMKL_AMPK_PRKAA1_ST	P04406	GAPDH	Q13131	PRKAA1	S83	D89G	89	Missense	distal	6	no	57.740	57.812	EPSD	TCGA;COSMIC	56.683	Up-regulation
CAMK_CAMKL_AMPK_PRKAA1_ST	P04406	GAPDH	Q13131	PRKAA1	S83	K84N	84	Missense	proximal	1	no	57.740	57.008	EPSD	TCGA	56.683	Down-regulation
CAMK_CAMKL_AMPK_PRKAA1_ST	P04406	GAPDH	Q13131	PRKAA1	S98	F102L	102	Missense	distal	4	no	52.704	56.899	EPSD	TCGA;COSMIC	56.683	Gain
CAMK_CAMKL_AMPK_PRKAA1_ST	P04406	GAPDH	Q13131	PRKAA1	S122	G115E	115	Missense	distal	-7	no	57.178	55.973	PhosphoSitePlus	TCGA;COSMIC	56.683	Loss
CAMK_CAMKL_AMPK_PRKAA1_ST	P04406	GAPDH	Q13131	PRKAA1	T237	A232T	232	Missense	distal	-5	no	66.762	64.770	EPSD	TCGA;COSMIC	56.683	Down-regulation
CAMK_CAMKL_AMPK_PRKAA1_ST	P04406	GAPDH	Q13131	PRKAA1	T237	A238S	238	Missense	proximal	1	no	66.762	68.357	EPSD	TCGA;COSMIC	56.683	Up-regulation
CAMK_CAMKL_AMPK_PRKAA1_ST	P04406	GAPDH	Q13131	PRKAA1	S241	A238S	238	Missense	distal	-3	no	57.768	59.230	EPSD	TCGA;COSMIC	56.683	Up-regulation
CAMK_CAMKL_AMPK_PRKAA1_ST	P04406	GAPDH	Q13131	PRKAA1	T294	G298W	298	Missense	distal	4	no	51.839	57.291	EPSD	TCGA;COSMIC	56.683	Gain
CAMK_CAMKL_AMPK_PRKAA1_ST	Q06210	GFPT1	Q13131	PRKAA1	S261	R258H	258	Missense	distal	-3	no	65.769	57.913	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	56.683	Down-regulation
CAMK_CAMKL_AMPK_PRKAA1_ST	P29474	NOS3	Q13131	PRKAA1	S260	R262Q	262	Missense	proximal	2	no	57.537	57.060	EPSD	TCGA;ICGC;COSMIC	56.683	Down-regulation
CAMK_CAMKL_AMPK_PRKAA1_ST	P29474	NOS3	Q13131	PRKAA1	T495	T488A	488	Missense	distal	-7	no	60.541	59.692	EPSD	TCGA;ICGC;COSMIC	56.683	Down-regulation
CAMK_CAMKL_AMPK_PRKAA1_ST	P29474	NOS3	Q13131	PRKAA1	S615	R612C	612	Missense	distal	-3	no	58.693	44.546	EPSD	TCGA;ICGC;COSMIC	56.683	Loss
CAMK_CAMKL_AMPK_PRKAA1_ST	P29474	NOS3	Q13131	PRKAA1	S615	S617F	617	Missense	proximal	2	no	58.693	58.401	EPSD	TCGA;ICGC;COSMIC;GDSC	56.683	Down-regulation
CAMK_CAMKL_AMPK_PRKAA1_ST	P29474	NOS3	Q13131	PRKAA1	S615	R612H	612	Missense	distal	-3	no	58.693	50.837	EPSD	TCGA;ICGC;COSMIC	56.683	Loss
CAMK_CAMKL_AMPK_PRKAA1_ST	P29474	NOS3	Q13131	PRKAA1	S633	G640V	640	Missense	distal	7	no	77.542	75.303	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	56.683	Down-regulation
CAMK_CAMKL_AMPK_PRKAA1_ST	P29474	NOS3	Q13131	PRKAA1	S634	G640V	640	Missense	distal	6	no	61.470	61.587	EPSD	TCGA;ICGC;COSMIC	56.683	Up-regulation
CAMK_CAMKL_AMPK_PRKAA1_ST	P29474	NOS3	Q13131	PRKAA1	T785	L783M	783	Missense	proximal	-2	no	60.258	60.270	EPSD	TCGA;ICGC;COSMIC	56.683	Up-regulation
CAMK_CAMKL_AMPK_PRKAA1_ST	P29474	NOS3	Q13131	PRKAA1	S870	D864N	864	Missense	distal	-6	no	61.669	59.404	EPSD	TCGA;ICGC;COSMIC	56.683	Down-regulation
CAMK_CAMKL_AMPK_PRKAA1_ST	P29474	NOS3	Q13131	PRKAA1	S870	S867T	867	Missense	distal	-3	no	61.669	56.953	EPSD	TCGA;ICGC;COSMIC	56.683	Down-regulation
CAMK_CAMKL_AMPK_PRKAA1_ST	P29474	NOS3	Q13131	PRKAA1	S870	R875W	875	Missense	distal	5	no	61.669	61.540	EPSD	TCGA;ICGC;COSMIC	56.683	Down-regulation
CAMK_CAMKL_AMPK_PRKAA1_ST	P29474	NOS3	Q13131	PRKAA1	S1177	R1172H	1172	Missense	distal	-5	no	71.268	65.887	PhosphoSitePlus;EPSD	TCGA;ICGC;COSMIC;GDSC;CCLE	56.683	Down-regulation
CAMK_CAMKL_AMPK_PRKAA1_ST	P29474	NOS3	Q13131	PRKAA1	S1177	E1182A	1182	Missense	distal	5	no	71.268	71.359	PhosphoSitePlus;EPSD	TCGA;ICGC;COSMIC	56.683	Up-regulation
CAMK_CAMKL_AMPK_PRKAA1_ST	P29474	NOS3	Q13131	PRKAA1	S1177	R1183C	1183	Missense	distal	6	no	71.268	71.599	PhosphoSitePlus;EPSD	TCGA;ICGC;COSMIC	56.683	Up-regulation
CAMK_CAMKL_AMPK_PRKAA1_ST	P29474	NOS3	Q13131	PRKAA1	S1177	R1174H	1174	Missense	distal	-3	no	71.268	63.411	PhosphoSitePlus;EPSD	TCGA;ICGC	56.683	Down-regulation
CAMK_CAMKL_AMPK_PRKAA1_ST	P29474	NOS3	Q13131	PRKAA1	S1179	R1172H	1172	Missense	distal	-7	no	63.880	60.857	EPSD	TCGA;ICGC;COSMIC;GDSC;CCLE	56.683	Down-regulation
CAMK_CAMKL_AMPK_PRKAA1_ST	P29474	NOS3	Q13131	PRKAA1	S1179	E1182A	1182	Missense	distal	3	no	63.880	60.870	EPSD	TCGA;ICGC;COSMIC	56.683	Down-regulation
CAMK_CAMKL_AMPK_PRKAA1_ST	P29474	NOS3	Q13131	PRKAA1	S1179	R1183C	1183	Missense	distal	4	no	63.880	43.027	EPSD	TCGA;ICGC;COSMIC	56.683	Loss
CAMK_CAMKL_AMPK_PRKAA1_ST	P29474	NOS3	Q13131	PRKAA1	S1179	R1174H	1174	Missense	distal	-5	no	63.880	58.500	EPSD	TCGA;ICGC	56.683	Down-regulation
CAMK_CAMKL_AMPK_PRKAA1_ST	P29474	NOS3	Q13131	PRKAA1	S1198	D1194V	1194	Missense	distal	-4	no	57.967	55.604	EPSD	TCGA;ICGC;COSMIC	56.683	Loss
CAMK_CAMKL_AMPK_PRKAA1_ST	P29474	NOS3	Q13131	PRKAA1	S1198	A1192V	1192	Missense	distal	-6	no	57.967	56.115	EPSD	TCGA;ICGC;GDSC;CCLE	56.683	Loss
CAMK_CAMKL_AMPK_PRKAA1_ST	P50552	VASP	Q13131	PRKAA1	S134	V129A	129	Missense	distal	-5	no	60.421	61.614	EPSD	TCGA;ICGC;COSMIC	56.683	Up-regulation
CAMK_CAMKL_AMPK_PRKAA1_ST	P50552	VASP	Q13131	PRKAA1	S157	R154C	154	Missense	distal	-3	no	63.922	49.775	EPSD	TCGA;ICGC;COSMIC	56.683	Loss
CAMK_CAMKL_AMPK_PRKAA1_ST	P50552	VASP	Q13131	PRKAA1	S303	R298T	298	Missense	distal	-5	no	56.685	52.198	EPSD	TCGA;ICGC;COSMIC	56.683	Loss
CAMK_CAMKL_AMPK_PRKAA1_ST	P50552	VASP	Q13131	PRKAA1	S303	W310C	310	Missense	distal	7	no	56.685	56.493	EPSD	TCGA;ICGC	56.683	Loss
CAMK_CAMKL_AMPK_PRKAA1_ST	P50552	VASP	Q13131	PRKAA1	S303	Q302H	302	Missense	proximal	-1	no	56.685	56.676	EPSD	TCGA;ICGC;COSMIC	56.683	Loss
CAMK_CAMKL_AMPK_PRKAA1_ST	P50552	VASP	Q13131	PRKAA1	S303	R307Q	307	Missense	distal	4	no	56.685	52.602	EPSD	TCGA;ICGC;COSMIC	56.683	Loss
CAMK_CAMKL_AMPK_PRKAA1_ST	P50552	VASP	Q13131	PRKAA1	S303	R307W	307	Missense	distal	4	no	56.685	59.936	EPSD	TCGA;ICGC	56.683	Up-regulation
CAMK_CAMKL_AMPK_PRKAA1_ST	P50552	VASP	Q13131	PRKAA1	T316	R319W	319	Missense	distal	3	no	54.944	57.003	EPSD	TCGA;ICGC;COSMIC	56.683	Gain
CAMK_CAMKL_AMPK_PRKAA1_ST	P50552	VASP	Q13131	PRKAA1	S322	R319W	319	Missense	distal	-3	no	67.825	-25.175	EPSD	TCGA;ICGC;COSMIC	56.683	Loss
CAMK_CAMKL_AMPK_PRKAA1_ST	P50552	VASP	Q13131	PRKAA1	S322	P318S	318	Missense	distal	-4	no	67.825	69.068	EPSD	TCGA;ICGC;COSMIC	56.683	Up-regulation
CAMK_CAMKL_AMPK_PRKAA1_ST	P50552	VASP	Q13131	PRKAA1	S338	T335A	335	Missense	distal	-3	no	58.626	61.879	EPSD	TCGA;ICGC;COSMIC	56.683	Up-regulation
CAMK_CAMKL_AMPK_PRKAA1_ST	Q13085	ACACA	Q13131	PRKAA1	S1438	L1442F	1442	Missense	distal	4	no	63.969	59.774	EPSD	TCGA	56.683	Down-regulation
CAMK_CAMKL_AMPK_PRKAA1_ST	Q9UQK1	PPP1R3C	Q13131	PRKAA1	S33	C29Y	29	Missense	distal	-4	no	67.935	59.699	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	56.683	Down-regulation
CAMK_CAMKL_AMPK_PRKAA1_ST	Q9UQK1	PPP1R3C	Q13131	PRKAA1	S33	P34T	34	Missense	proximal	1	no	67.935	67.525	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	56.683	Down-regulation
CAMK_CAMKL_AMPK_PRKAA1_ST	Q9UQK1	PPP1R3C	Q13131	PRKAA1	S33	R27S	27	Missense	distal	-6	no	67.935	67.464	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	56.683	Down-regulation
CAMK_CAMKL_AMPK_PRKAA1_ST	Q9UQK1	PPP1R3C	Q13131	PRKAA1	S33	R27M	27	Missense	distal	-6	no	67.935	66.623	EPSD;PhosphoSitePlus	TCGA;ICGC	56.683	Down-regulation
CAMK_CAMKL_AMPK_PRKAA1_ST	Q9UQK1	PPP1R3C	Q13131	PRKAA1	T170	R167Q	167	Missense	distal	-3	no	70.453	62.509	EPSD	TCGA;ICGC;COSMIC	56.683	Down-regulation
CAMK_CAMKL_AMPK_PRKAA1_ST	Q9UQK1	PPP1R3C	Q13131	PRKAA1	T170	S163L	163	Missense	distal	-7	no	70.453	68.025	EPSD	TCGA;ICGC;COSMIC	56.683	Down-regulation
CAMK_CAMKL_AMPK_PRKAA1_ST	Q9UQK1	PPP1R3C	Q13131	PRKAA1	S293	S298I	298	Missense	distal	5	no	57.511	57.474	PhosphoSitePlus;EPSD	TCGA;ICGC;COSMIC	56.683	Down-regulation
CAMK_CAMKL_AMPK_PRKAA1_ST	P23458	JAK1	Q13131	PRKAA1	T273	Y270H	270	Missense	distal	-3	no	51.321	59.695	EPSD	TCGA;ICGC	56.683	Gain
CAMK_CAMKL_AMPK_PRKAA1_ST	P23458	JAK1	Q13131	PRKAA1	S398	S398F	398	Missense	central	0	yes	63.125	0.000	EPSD	TCGA;ICGC;COSMIC	56.683	Loss
CAMK_CAMKL_AMPK_PRKAA1_ST	P23458	JAK1	Q13131	PRKAA1	S515	S512L	512	Missense	distal	-3	no	65.849	65.277	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	56.683	Down-regulation
CAMK_CAMKL_AMPK_PRKAA1_ST	P23458	JAK1	Q13131	PRKAA1	S518	H525Y	525	Missense	distal	7	no	58.438	59.999	PhosphoSitePlus;EPSD	TCGA;COSMIC;GDSC;CCLE	56.683	Up-regulation
CAMK_CAMKL_AMPK_PRKAA1_ST	P23458	JAK1	Q13131	PRKAA1	S518	S512L	512	Missense	distal	-6	no	58.438	58.748	PhosphoSitePlus;EPSD	TCGA;ICGC;COSMIC	56.683	Up-regulation
CAMK_CAMKL_AMPK_PRKAA1_ST	P23458	JAK1	Q13131	PRKAA1	T687	L686F	686	Missense	proximal	-1	no	59.014	58.942	EPSD	TCGA;ICGC;COSMIC	56.683	Down-regulation
CAMK_CAMKL_AMPK_PRKAA1_ST	P23458	JAK1	Q13131	PRKAA1	T687	D684N	684	Missense	distal	-3	no	59.014	62.930	EPSD	TCGA;ICGC;COSMIC	56.683	Up-regulation
CAMK_CAMKL_AMPK_PRKAA1_ST	P23458	JAK1	Q13131	PRKAA1	T687	R681Q	681	Missense	distal	-6	no	59.014	59.371	EPSD	TCGA;ICGC	56.683	Up-regulation
CAMK_CAMKL_AMPK_PRKAA1_ST	P23458	JAK1	Q13131	PRKAA1	T687	K691T	691	Missense	distal	4	no	59.014	57.400	EPSD	TCGA;ICGC	56.683	Down-regulation
CAMK_CAMKL_AMPK_PRKAA1_ST	P23458	JAK1	Q13131	PRKAA1	T1100	G1097C	1097	Missense	distal	-3	no	58.087	52.974	EPSD	TCGA;ICGC;COSMIC	56.683	Loss
CAMK_CAMKL_AMPK_PRKAA1_ST	P23458	JAK1	Q13131	PRKAA1	T1100	G1093C	1093	Missense	distal	-7	no	58.087	55.279	EPSD	TCGA;ICGC;COSMIC	56.683	Loss
CAMK_CAMKL_AMPK_PRKAA1_ST	P23458	JAK1	Q13131	PRKAA1	T1100	Q1098H	1098	Missense	proximal	-2	no	58.087	54.903	EPSD	TCGA;ICGC;COSMIC	56.683	Loss
CAMK_CAMKL_AMPK_PRKAA1_ST	P46937	YAP1	Q13131	PRKAA1	S61	S61W	61	Missense	central	0	yes	60.954	0.000	PhosphoSitePlus;EPSD	TCGA;ICGC;COSMIC	56.683	Loss
CAMK_CAMKL_AMPK_PRKAA1_ST	P46937	YAP1	Q13131	PRKAA1	S94	F95C	95	Missense	proximal	1	no	60.995	55.793	EPSD;PhosphoSitePlus	TCGA;ICGC	56.683	Loss
CAMK_CAMKL_AMPK_PRKAA1_ST	P46937	YAP1	Q13131	PRKAA1	S109	R106Q	106	Missense	distal	-3	no	59.066	51.122	EPSD	TCGA;ICGC;COSMIC;CCLE	56.683	Loss
CAMK_CAMKL_AMPK_PRKAA1_ST	P46937	YAP1	Q13131	PRKAA1	S109	S109N	109	Missense	central	0	yes	59.066	0.000	EPSD	TCGA;ICGC;COSMIC	56.683	Loss
CAMK_CAMKL_AMPK_PRKAA1_ST	P46937	YAP1	Q13131	PRKAA1	T110	R106Q	106	Missense	distal	-4	no	56.736	55.268	EPSD	TCGA;ICGC;COSMIC;CCLE	56.683	Loss
CAMK_CAMKL_AMPK_PRKAA1_ST	P46937	YAP1	Q13131	PRKAA1	T110	S109N	109	Missense	proximal	-1	no	56.736	56.697	EPSD	TCGA;ICGC;COSMIC	56.683	Down-regulation
CAMK_CAMKL_AMPK_PRKAA1_ST	P46937	YAP1	Q13131	PRKAA1	S229	P231H	231	Missense	proximal	2	no	57.527	57.373	EPSD	TCGA;ICGC;COSMIC	56.683	Down-regulation
CAMK_CAMKL_AMPK_PRKAA1_ST	P46937	YAP1	Q13131	PRKAA1	S366	S366C	366	Missense	central	0	yes	61.578	0.000	EPSD	TCGA	56.683	Loss
CAMK_CAMKL_AMPK_PRKAA1_ST	P46937	YAP1	Q13131	PRKAA1	S366	G369R	369	Missense	distal	3	no	61.578	59.725	EPSD	TCGA;ICGC	56.683	Down-regulation
CAMK_CAMKL_AMPK_PRKAA1_ST	P46937	YAP1	Q13131	PRKAA1	T378	D383E	383	Missense	distal	5	no	66.144	65.991	EPSD	TCGA;ICGC;COSMIC	56.683	Down-regulation
CAMK_CAMKL_AMPK_PRKAA1_ST	P46937	YAP1	Q13131	PRKAA1	S382	D383E	383	Missense	proximal	1	no	61.508	61.296	EPSD	TCGA;ICGC;COSMIC	56.683	Down-regulation
CAMK_CAMKL_AMPK_PRKAA1_ST	P46937	YAP1	Q13131	PRKAA1	T390	D383E	383	Missense	distal	-7	no	57.287	57.386	EPSD	TCGA;ICGC;COSMIC	56.683	Up-regulation
CAMK_CAMKL_AMPK_PRKAA1_ST	P46937	YAP1	Q13131	PRKAA1	T390	E396D	396	Missense	distal	6	no	57.287	56.814	EPSD	TCGA;ICGC;COSMIC	56.683	Down-regulation
CAMK_CAMKL_AMPK_PRKAA1_ST	P46937	YAP1	Q13131	PRKAA1	S406	P413Q	413	Missense	distal	7	no	61.336	62.612	EPSD	TCGA;ICGC;COSMIC	56.683	Up-regulation
CAMK_CAMKL_AMPK_PRKAA1_ST	P46937	YAP1	Q13131	PRKAA1	T412	P413Q	413	Missense	proximal	1	no	57.206	55.972	EPSD	TCGA;ICGC;COSMIC	56.683	Loss
CAMK_CAMKL_AMPK_PRKAA1_ST	P46937	YAP1	Q13131	PRKAA1	S499	L501F	501	Missense	proximal	2	no	57.882	57.645	EPSD	TCGA;ICGC;COSMIC	56.683	Down-regulation
CAMK_CAMKL_AMPK_PRKAA1_ST	Q13950	RUNX2	Q13131	PRKAA1	S28	P29T	29	Missense	proximal	1	no	57.931	57.520	EPSD	TCGA;COSMIC	56.683	Down-regulation
CAMK_CAMKL_AMPK_PRKAA1_ST	Q13950	RUNX2	Q13131	PRKAA1	S28	P29S	29	Missense	proximal	1	no	57.931	58.563	EPSD	TCGA;COSMIC	56.683	Up-regulation
CAMK_CAMKL_AMPK_PRKAA1_ST	Q13950	RUNX2	Q13131	PRKAA1	S196	R193Q	193	Missense	distal	-3	no	74.997	67.053	EPSD	TCGA;COSMIC	56.683	Down-regulation
CAMK_CAMKL_AMPK_PRKAA1_ST	Q13950	RUNX2	Q13131	PRKAA1	S196	V203I	203	Missense	distal	7	no	74.997	76.195	EPSD	TCGA;COSMIC	56.683	Up-regulation
CAMK_CAMKL_AMPK_PRKAA1_ST	Q13950	RUNX2	Q13131	PRKAA1	S196	K195N	195	Missense	proximal	-1	no	74.997	75.064	EPSD	TCGA;COSMIC	56.683	Up-regulation
CAMK_CAMKL_AMPK_PRKAA1_ST	Q13950	RUNX2	Q13131	PRKAA1	S196	T202A	202	Missense	distal	6	no	74.997	75.157	EPSD	TCGA;COSMIC	56.683	Up-regulation
CAMK_CAMKL_AMPK_PRKAA1_ST	Q13950	RUNX2	Q13131	PRKAA1	S196	R190W	190	Missense	distal	-6	no	74.997	70.185	EPSD	TCGA;COSMIC	56.683	Down-regulation
CAMK_CAMKL_AMPK_PRKAA1_ST	Q13950	RUNX2	Q13131	PRKAA1	S293	P296S	296	Missense	distal	3	no	56.131	58.368	EPSD	TCGA;COSMIC	56.683	Gain
CAMK_CAMKL_AMPK_PRKAA1_ST	Q13950	RUNX2	Q13131	PRKAA1	S298	P296S	296	Missense	proximal	-2	no	60.621	60.072	EPSD	TCGA;COSMIC	56.683	Down-regulation
CAMK_CAMKL_AMPK_PRKAA1_ST	Q13950	RUNX2	Q13131	PRKAA1	S340	D341Y	341	Missense	proximal	1	no	53.969	57.125	EPSD	TCGA;COSMIC	56.683	Gain
CAMK_CAMKL_AMPK_PRKAA1_ST	Q13950	RUNX2	Q13131	PRKAA1	S465	P460S	460	Missense	distal	-5	no	56.461	57.019	EPSD	TCGA;COSMIC	56.683	Gain
CAMK_CAMKL_AMPK_PRKAA1_ST	Q13950	RUNX2	Q13131	PRKAA1	S465	P466S	466	Missense	proximal	1	no	56.461	57.094	EPSD	TCGA;COSMIC	56.683	Gain
CAMK_CAMKL_AMPK_PRKAA1_ST	Q13950	RUNX2	Q13131	PRKAA1	S499	V506F	506	Missense	distal	7	no	56.232	57.254	EPSD	TCGA;COSMIC	56.683	Gain
CAMK_CAMKL_AMPK_PRKAA1_ST	Q13950	RUNX2	Q13131	PRKAA1	S503	V506F	506	Missense	distal	3	no	59.375	57.270	EPSD	TCGA;COSMIC	56.683	Down-regulation
CAMK_CAMKL_AMPK_PRKAA1_ST	Q13950	RUNX2	Q13131	PRKAA1	S503	S503Y	503	Missense	central	0	yes	59.375	0.000	EPSD	TCGA;COSMIC	56.683	Loss
CAMK_CAMKL_AMPK_PRKAA1_ST	Q9NYV6	RRN3	Q13131	PRKAA1	S172	E175K	175	Missense	distal	3	no	55.065	56.789	EPSD	TCGA;ICGC;COSMIC	56.683	Gain
CAMK_CAMKL_AMPK_PRKAA1_ST	Q9NYV6	RRN3	Q13131	PRKAA1	S635	S640F	640	Missense	distal	5	no	58.671	58.542	PhosphoSitePlus	TCGA;COSMIC	56.683	Down-regulation
CAMK_CAMKL_AMPK_PRKAA1_ST	Q9NYV6	RRN3	Q13131	PRKAA1	S635	P641S	641	Missense	distal	6	no	58.671	58.686	PhosphoSitePlus	TCGA;COSMIC	56.683	Up-regulation
CAMK_CAMKL_AMPK_PRKAA1_ST	Q9NYV6	RRN3	Q13131	PRKAA1	S635	F631L	631	Missense	distal	-4	no	58.671	59.023	PhosphoSitePlus	TCGA;COSMIC	56.683	Up-regulation
CAMK_CAMKL_AMPK_PRKAA1_ST	Q9NYV6	RRN3	Q13131	PRKAA1	S636	F631L	631	Missense	distal	-5	no	52.382	57.906	EPSD	TCGA;COSMIC	56.683	Gain
CAMK_CAMKL_AMPK_PRKAA1_ST	Q9NYV6	RRN3	Q13131	PRKAA1	S640	S640F	640	Missense	central	0	yes	62.664	0.000	EPSD	TCGA;COSMIC	56.683	Loss
CAMK_CAMKL_AMPK_PRKAA1_ST	Q9NYV6	RRN3	Q13131	PRKAA1	S640	P641S	641	Missense	proximal	1	no	62.664	63.296	EPSD	TCGA;COSMIC	56.683	Up-regulation
CAMK_CAMKL_AMPK_PRKAA1_ST	Q9H0B6	KLC2	Q13131	PRKAA1	T163	V159I	159	Missense	distal	-4	no	67.657	66.251	EPSD	TCGA;COSMIC	56.683	Down-regulation
CAMK_CAMKL_AMPK_PRKAA1_ST	Q9H0B6	KLC2	Q13131	PRKAA1	S445	L452P	452	Missense	distal	7	no	61.611	61.071	EPSD	TCGA;COSMIC	56.683	Down-regulation
CAMK_CAMKL_AMPK_PRKAA1_ST	Q9H0B6	KLC2	Q13131	PRKAA1	S445	T447A	447	Missense	proximal	2	no	61.611	61.165	EPSD	TCGA;ICGC	56.683	Down-regulation
CAMK_CAMKL_AMPK_PRKAA1_ST	Q9H0B6	KLC2	Q13131	PRKAA1	S499	R506C	506	Missense	distal	7	no	59.269	59.302	EPSD	TCGA;ICGC;COSMIC;CCLE	56.683	Up-regulation
CAMK_CAMKL_AMPK_PRKAA1_ST	Q9H0B6	KLC2	Q13131	PRKAA1	S499	R505H	505	Missense	distal	6	no	59.269	59.375	EPSD	TCGA	56.683	Up-regulation
CAMK_CAMKL_AMPK_PRKAA1_ST	Q9H0B6	KLC2	Q13131	PRKAA1	S499	R506H	506	Missense	distal	7	no	59.269	58.543	EPSD	TCGA;ICGC	56.683	Down-regulation
CAMK_CAMKL_AMPK_PRKAA1_ST	Q9H0B6	KLC2	Q13131	PRKAA1	S545	R542C	542	Missense	distal	-3	no	79.895	65.748	PhosphoSitePlus;EPSD	TCGA;COSMIC	56.683	Down-regulation
CAMK_CAMKL_AMPK_PRKAA1_ST	Q9H0B6	KLC2	Q13131	PRKAA1	S545	R542H	542	Missense	distal	-3	no	79.895	72.038	PhosphoSitePlus;EPSD	TCGA;ICGC;COSMIC;CCLE	56.683	Down-regulation
CAMK_CAMKL_AMPK_PRKAA1_ST	Q9H0B6	KLC2	Q13131	PRKAA1	S545	L549I	549	Missense	distal	4	no	79.895	76.819	PhosphoSitePlus;EPSD	TCGA	56.683	Down-regulation
CAMK_CAMKL_AMPK_PRKAA1_ST	Q9H0B6	KLC2	Q13131	PRKAA1	S557	R555C	555	Missense	proximal	-2	no	62.084	54.973	EPSD	TCGA;ICGC;COSMIC	56.683	Loss
CAMK_CAMKL_AMPK_PRKAA1_ST	Q9H0B6	KLC2	Q13131	PRKAA1	S581	R579Q	579	Missense	proximal	-2	no	59.791	60.253	EPSD	TCGA;ICGC;COSMIC	56.683	Up-regulation
CAMK_CAMKL_AMPK_PRKAA1_ST	Q9H0B6	KLC2	Q13131	PRKAA1	S582	R579Q	579	Missense	distal	-3	no	66.356	58.412	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	56.683	Down-regulation
CAMK_CAMKL_AMPK_PRKAA1_ST	Q9H0B6	KLC2	Q13131	PRKAA1	S608	R605H	605	Missense	distal	-3	no	61.647	53.790	EPSD	TCGA;COSMIC	56.683	Loss
CAMK_CAMKL_AMPK_PRKAA1_ST	Q9H0B6	KLC2	Q13131	PRKAA1	S610	R605H	605	Missense	distal	-5	no	57.916	52.536	EPSD	TCGA;COSMIC	56.683	Loss
CAMK_CAMKL_AMPK_PRKAA1_ST	Q9H0B6	KLC2	Q13131	PRKAA1	S610	R617Q	617	Missense	distal	7	no	57.916	59.281	EPSD	TCGA;ICGC;COSMIC	56.683	Up-regulation
CAMK_CAMKL_AMPK_PRKAA1_ST	P09874	PARP1	Q13131	PRKAA1	S343	V350I	350	Missense	distal	7	no	60.884	62.082	EPSD	TCGA;ICGC;COSMIC	56.683	Up-regulation
CAMK_CAMKL_AMPK_PRKAA1_ST	P09874	PARP1	Q13131	PRKAA1	T361	T368M	368	Missense	distal	7	no	60.148	58.432	EPSD	TCGA;GDSC;CCLE	56.683	Down-regulation
CAMK_CAMKL_AMPK_PRKAA1_ST	P09874	PARP1	Q13131	PRKAA1	T361	E360V	360	Missense	proximal	-1	no	60.148	60.159	EPSD	TCGA;ICGC;COSMIC	56.683	Up-regulation
CAMK_CAMKL_AMPK_PRKAA1_ST	P09874	PARP1	Q13131	PRKAA1	T361	A363T	363	Missense	proximal	2	no	60.148	60.594	EPSD	TCGA;ICGC;COSMIC	56.683	Up-regulation
CAMK_CAMKL_AMPK_PRKAA1_ST	P09874	PARP1	Q13131	PRKAA1	T361	V365M	365	Missense	distal	4	no	60.148	62.068	EPSD	TCGA;ICGC;COSMIC	56.683	Up-regulation
CAMK_CAMKL_AMPK_PRKAA1_ST	P09874	PARP1	Q13131	PRKAA1	S479	H476R	476	Missense	distal	-3	no	54.967	62.824	EPSD	TCGA;ICGC	56.683	Gain
CAMK_CAMKL_AMPK_PRKAA1_ST	P09874	PARP1	Q13131	PRKAA1	S507	L503R	503	Missense	distal	-4	no	61.478	64.038	EPSD	TCGA;ICGC;COSMIC	56.683	Up-regulation
CAMK_CAMKL_AMPK_PRKAA1_ST	P09874	PARP1	Q13131	PRKAA1	S507	V511I	511	Missense	distal	4	no	61.478	62.899	EPSD	TCGA;ICGC;COSMIC	56.683	Up-regulation
CAMK_CAMKL_AMPK_PRKAA1_ST	P09874	PARP1	Q13131	PRKAA1	S507	K512E	512	Missense	distal	5	no	61.478	61.457	EPSD	TCGA;ICGC;COSMIC	56.683	Down-regulation
CAMK_CAMKL_AMPK_PRKAA1_ST	P09874	PARP1	Q13131	PRKAA1	S507	A501T	501	Missense	distal	-6	no	61.478	61.276	EPSD	TCGA;ICGC;COSMIC	56.683	Down-regulation
CAMK_CAMKL_AMPK_PRKAA1_ST	P09874	PARP1	Q13131	PRKAA1	S507	E514G	514	Missense	distal	7	no	61.478	62.204	EPSD	TCGA;ICGC;COSMIC	56.683	Up-regulation
CAMK_CAMKL_AMPK_PRKAA1_ST	P09874	PARP1	Q13131	PRKAA1	S519	K512E	512	Missense	distal	-7	no	63.180	61.787	EPSD	TCGA;ICGC;COSMIC	56.683	Down-regulation
CAMK_CAMKL_AMPK_PRKAA1_ST	P09874	PARP1	Q13131	PRKAA1	S519	E514G	514	Missense	distal	-5	no	63.180	60.613	EPSD	TCGA;ICGC;COSMIC	56.683	Down-regulation
CAMK_CAMKL_AMPK_PRKAA1_ST	P09874	PARP1	Q13131	PRKAA1	S519	M523I	523	Missense	distal	4	no	63.180	62.680	EPSD	TCGA;ICGC	56.683	Down-regulation
CAMK_CAMKL_AMPK_PRKAA1_ST	P09874	PARP1	Q13131	PRKAA1	S606	S606F	606	Missense	central	0	yes	58.313	0.000	EPSD	TCGA;ICGC;COSMIC	56.683	Loss
CAMK_CAMKL_AMPK_PRKAA1_ST	P09874	PARP1	Q13131	PRKAA1	T661	T656I	656	Missense	distal	-5	no	56.135	62.377	EPSD	TCGA;ICGC;COSMIC	56.683	Gain
CAMK_CAMKL_AMPK_PRKAA1_ST	P09874	PARP1	Q13131	PRKAA1	S681	E680Q	680	Missense	proximal	-1	no	69.737	69.813	EPSD	TCGA;ICGC;COSMIC	56.683	Up-regulation
CAMK_CAMKL_AMPK_PRKAA1_ST	P52292	KPNA2	Q13131	PRKAA1	S54	T61A	61	Missense	distal	7	no	64.161	64.536	EPSD	TCGA;ICGC;COSMIC	56.683	Up-regulation
CAMK_CAMKL_AMPK_PRKAA1_ST	P52292	KPNA2	Q13131	PRKAA1	S54	D59N	59	Missense	distal	5	no	64.161	64.017	EPSD	TCGA;ICGC;COSMIC	56.683	Down-regulation
CAMK_CAMKL_AMPK_PRKAA1_ST	P52292	KPNA2	Q13131	PRKAA1	S54	P57S	57	Missense	distal	3	no	64.161	66.399	EPSD	TCGA;ICGC;COSMIC	56.683	Up-regulation
CAMK_CAMKL_AMPK_PRKAA1_ST	P52292	KPNA2	Q13131	PRKAA1	S54	R51I	51	Missense	distal	-3	no	64.161	50.763	EPSD	TCGA;ICGC;COSMIC	56.683	Loss
CAMK_CAMKL_AMPK_PRKAA1_ST	P52292	KPNA2	Q13131	PRKAA1	S55	T61A	61	Missense	distal	6	no	58.087	58.247	EPSD	TCGA;ICGC;COSMIC	56.683	Up-regulation
CAMK_CAMKL_AMPK_PRKAA1_ST	P52292	KPNA2	Q13131	PRKAA1	S55	D59N	59	Missense	distal	4	no	58.087	57.354	EPSD	TCGA;ICGC;COSMIC	56.683	Down-regulation
CAMK_CAMKL_AMPK_PRKAA1_ST	P52292	KPNA2	Q13131	PRKAA1	S55	P57S	57	Missense	proximal	2	no	58.087	57.543	EPSD	TCGA;ICGC;COSMIC	56.683	Down-regulation
CAMK_CAMKL_AMPK_PRKAA1_ST	P52292	KPNA2	Q13131	PRKAA1	S55	R51I	51	Missense	distal	-4	no	58.087	54.224	EPSD	TCGA;ICGC;COSMIC	56.683	Loss
CAMK_CAMKL_AMPK_PRKAA1_ST	P52292	KPNA2	Q13131	PRKAA1	S62	D59N	59	Missense	distal	-3	no	53.745	57.662	EPSD	TCGA;ICGC;COSMIC	56.683	Gain
CAMK_CAMKL_AMPK_PRKAA1_ST	P52292	KPNA2	Q13131	PRKAA1	S105	P110S	110	Missense	distal	5	no	57.175	57.137	PhosphoSitePlus	TCGA;ICGC;COSMIC	56.683	Down-regulation
CAMK_CAMKL_AMPK_PRKAA1_ST	P52292	KPNA2	Q13131	PRKAA1	S105	Q109H	109	Missense	distal	4	no	57.175	58.258	PhosphoSitePlus	TCGA;ICGC;COSMIC	56.683	Up-regulation
CAMK_CAMKL_AMPK_PRKAA1_ST	P52292	KPNA2	Q13131	PRKAA1	T232	S234C	234	Missense	proximal	2	no	58.401	57.104	EPSD	TCGA;ICGC;COSMIC	56.683	Down-regulation
CAMK_CAMKL_AMPK_PRKAA1_ST	P52292	KPNA2	Q13131	PRKAA1	T232	L233H	233	Missense	proximal	1	no	58.401	61.337	EPSD	TCGA;ICGC;COSMIC	56.683	Up-regulation
CAMK_CAMKL_AMPK_PRKAA1_ST	P52292	KPNA2	Q13131	PRKAA1	T232	R227C	227	Missense	distal	-5	no	58.401	57.047	EPSD	TCGA;ICGC;COSMIC	56.683	Down-regulation
CAMK_CAMKL_AMPK_PRKAA1_ST	P52292	KPNA2	Q13131	PRKAA1	T232	R238H	238	Missense	distal	6	no	58.401	58.506	EPSD	TCGA;ICGC;COSMIC	56.683	Up-regulation
CAMK_CAMKL_AMPK_PRKAA1_ST	P52292	KPNA2	Q13131	PRKAA1	T255	R258W	258	Missense	distal	3	no	55.001	57.059	EPSD	TCGA;ICGC;COSMIC;CCLE	56.683	Gain
CAMK_CAMKL_AMPK_PRKAA1_ST	O00418	EEF2K	Q13131	PRKAA1	S70	E67K	67	Missense	distal	-3	no	53.183	57.023	EPSD	TCGA;ICGC;COSMIC	56.683	Gain
CAMK_CAMKL_AMPK_PRKAA1_ST	O00418	EEF2K	Q13131	PRKAA1	S74	E67K	67	Missense	distal	-7	no	56.318	57.711	EPSD	TCGA;ICGC;COSMIC	56.683	Gain
CAMK_CAMKL_AMPK_PRKAA1_ST	O00418	EEF2K	Q13131	PRKAA1	S78	H80Y	80	Missense	proximal	2	no	58.426	57.570	EPSD	TCGA;ICGC;COSMIC	56.683	Down-regulation
CAMK_CAMKL_AMPK_PRKAA1_ST	O00418	EEF2K	Q13131	PRKAA1	S78	S74C	74	Missense	distal	-4	no	58.426	63.801	EPSD	TCGA;ICGC;COSMIC	56.683	Up-regulation
CAMK_CAMKL_AMPK_PRKAA1_ST	O00418	EEF2K	Q13131	PRKAA1	S359	S366F	366	Missense	distal	7	no	60.593	59.325	EPSD	TCGA;ICGC;COSMIC	56.683	Down-regulation
CAMK_CAMKL_AMPK_PRKAA1_ST	O00418	EEF2K	Q13131	PRKAA1	S359	S366C	366	Missense	distal	7	no	60.593	60.040	EPSD	TCGA;ICGC;COSMIC	56.683	Down-regulation
CAMK_CAMKL_AMPK_PRKAA1_ST	O00418	EEF2K	Q13131	PRKAA1	S368	S366F	366	Missense	proximal	-2	no	56.835	54.637	EPSD	TCGA;ICGC;COSMIC	56.683	Loss
CAMK_CAMKL_AMPK_PRKAA1_ST	O00418	EEF2K	Q13131	PRKAA1	S368	S366C	366	Missense	proximal	-2	no	56.835	48.485	EPSD	TCGA;ICGC;COSMIC	56.683	Loss
CAMK_CAMKL_AMPK_PRKAA1_ST	O00418	EEF2K	Q13131	PRKAA1	S368	P371S	371	Missense	distal	3	no	56.835	59.073	EPSD	TCGA;ICGC;COSMIC	56.683	Up-regulation
CAMK_CAMKL_AMPK_PRKAA1_ST	O00418	EEF2K	Q13131	PRKAA1	S377	P371S	371	Missense	distal	-6	no	58.008	57.658	EPSD	TCGA;ICGC;COSMIC	56.683	Down-regulation
CAMK_CAMKL_AMPK_PRKAA1_ST	O00418	EEF2K	Q13131	PRKAA1	S398	A400V	400	Missense	proximal	2	no	62.228	63.374	PhosphoSitePlus	TCGA;ICGC;COSMIC	56.683	Up-regulation
CAMK_CAMKL_AMPK_PRKAA1_ST	O00418	EEF2K	Q13131	PRKAA1	S398	S396F	396	Missense	proximal	-2	no	62.228	60.030	PhosphoSitePlus	TCGA;ICGC;COSMIC	56.683	Down-regulation
CAMK_CAMKL_AMPK_PRKAA1_ST	O00418	EEF2K	Q13131	PRKAA1	S398	S392F	392	Missense	distal	-6	no	62.228	62.331	PhosphoSitePlus	TCGA;ICGC;COSMIC	56.683	Up-regulation
CAMK_CAMKL_AMPK_PRKAA1_ST	O00418	EEF2K	Q13131	PRKAA1	S398	D391N	391	Missense	distal	-7	no	62.228	62.022	PhosphoSitePlus	TCGA;ICGC	56.683	Down-regulation
CAMK_CAMKL_AMPK_PRKAA1_ST	O60825	PFKFB2	Q13131	PRKAA1	S13	K17E	17	Missense	distal	4	no	63.551	57.795	EPSD	TCGA;ICGC;COSMIC	56.683	Down-regulation
CAMK_CAMKL_AMPK_PRKAA1_ST	O60825	PFKFB2	Q13131	PRKAA1	S13	S6F	6	Missense	distal	-7	no	63.551	60.959	EPSD	TCGA;ICGC;COSMIC	56.683	Down-regulation
CAMK_CAMKL_AMPK_PRKAA1_ST	O60825	PFKFB2	Q13131	PRKAA1	T52	R49W	49	Missense	distal	-3	no	59.424	-33.576	EPSD	TCGA;COSMIC	56.683	Loss
CAMK_CAMKL_AMPK_PRKAA1_ST	O60825	PFKFB2	Q13131	PRKAA1	S174	V173I	173	Missense	proximal	-1	no	57.927	58.011	EPSD	TCGA;COSMIC	56.683	Up-regulation
CAMK_CAMKL_AMPK_PRKAA1_ST	O60825	PFKFB2	Q13131	PRKAA1	S214	V221M	221	Missense	distal	7	no	57.521	57.849	EPSD	TCGA;GDSC;CCLE	56.683	Up-regulation
CAMK_CAMKL_AMPK_PRKAA1_ST	O60825	PFKFB2	Q13131	PRKAA1	S214	V218A	218	Missense	distal	4	no	57.521	57.487	EPSD	TCGA;COSMIC	56.683	Down-regulation
CAMK_CAMKL_AMPK_PRKAA1_ST	O60825	PFKFB2	Q13131	PRKAA1	S214	D207N	207	Missense	distal	-7	no	57.521	57.315	EPSD	TCGA;COSMIC	56.683	Down-regulation
CAMK_CAMKL_AMPK_PRKAA1_ST	O60825	PFKFB2	Q13131	PRKAA1	T458	F453V	453	Missense	distal	-5	no	57.719	58.379	EPSD	TCGA;COSMIC;CCLE	56.683	Up-regulation
CAMK_CAMKL_AMPK_PRKAA1_ST	O60825	PFKFB2	Q13131	PRKAA1	T458	K455N	455	Missense	distal	-3	no	57.719	56.424	EPSD	TCGA;COSMIC	56.683	Loss
CAMK_CAMKL_AMPK_PRKAA1_ST	O60825	PFKFB2	Q13131	PRKAA1	S483	R478H	478	Missense	distal	-5	no	60.167	54.787	EPSD	TCGA;COSMIC	56.683	Loss
CAMK_CAMKL_AMPK_PRKAA1_ST	O60825	PFKFB2	Q13131	PRKAA1	S483	G485W	485	Missense	proximal	2	no	60.167	60.855	EPSD	TCGA;COSMIC	56.683	Up-regulation
CAMK_CAMKL_AMPK_PRKAA1_ST	O60825	PFKFB2	Q13131	PRKAA1	S483	R480I	480	Missense	distal	-3	no	60.167	46.769	EPSD	TCGA;COSMIC	56.683	Loss
CAMK_CAMKL_AMPK_PRKAA1_ST	O60825	PFKFB2	Q13131	PRKAA1	S483	V484I	484	Missense	proximal	1	no	60.167	58.724	EPSD	TCGA;COSMIC	56.683	Down-regulation
CAMK_CAMKL_AMPK_PRKAA1_ST	O60825	PFKFB2	Q13131	PRKAA1	S493	R496P	496	Missense	distal	3	no	59.079	57.492	EPSD	TCGA;COSMIC	56.683	Down-regulation
CAMK_CAMKL_AMPK_PRKAA1_ST	O60825	PFKFB2	Q13131	PRKAA1	S493	D499V	499	Missense	distal	6	no	59.079	59.268	EPSD	TCGA;COSMIC	56.683	Up-regulation
CAMK_CAMKL_AMPK_PRKAA1_ST	O60825	PFKFB2	Q13131	PRKAA1	S493	L495F	495	Missense	proximal	2	no	59.079	58.843	EPSD	TCGA;COSMIC	56.683	Down-regulation
CAMK_CAMKL_AMPK_PRKAA1_ST	P13569	CFTR	Q13131	PRKAA1	S466	S459F	459	Missense	distal	-7	no	57.751	55.158	EPSD	TCGA;ICGC;COSMIC	56.683	Loss
CAMK_CAMKL_AMPK_PRKAA1_ST	P13569	CFTR	Q13131	PRKAA1	S686	E681D	681	Missense	distal	-5	no	67.697	64.281	EPSD	TCGA;ICGC;COSMIC	56.683	Down-regulation
CAMK_CAMKL_AMPK_PRKAA1_ST	P13569	CFTR	Q13131	PRKAA1	S712	S712F	712	Missense	central	0	yes	58.167	0.000	EPSD	TCGA;COSMIC	56.683	Loss
CAMK_CAMKL_AMPK_PRKAA1_ST	P13569	CFTR	Q13131	PRKAA1	S712	R709Q	709	Missense	distal	-3	no	58.167	50.223	EPSD	TCGA;COSMIC	56.683	Loss
CAMK_CAMKL_AMPK_PRKAA1_ST	P13569	CFTR	Q13131	PRKAA1	S712	K716N	716	Missense	distal	4	no	58.167	55.594	EPSD	TCGA;COSMIC	56.683	Loss
CAMK_CAMKL_AMPK_PRKAA1_ST	P13569	CFTR	Q13131	PRKAA1	S712	S707Y	707	Missense	distal	-5	no	58.167	57.312	EPSD	TCGA	56.683	Down-regulation
CAMK_CAMKL_AMPK_PRKAA1_ST	P13569	CFTR	Q13131	PRKAA1	S737	Q744L	744	Missense	distal	7	no	61.506	60.770	PhosphoSitePlus;EPSD	TCGA;COSMIC	56.683	Down-regulation
CAMK_CAMKL_AMPK_PRKAA1_ST	P13569	CFTR	Q13131	PRKAA1	S737	D741N	741	Missense	distal	4	no	61.506	60.774	PhosphoSitePlus;EPSD	TCGA;COSMIC	56.683	Down-regulation
CAMK_CAMKL_AMPK_PRKAA1_ST	P13569	CFTR	Q13131	PRKAA1	S768	T774I	774	Missense	distal	6	no	65.934	65.678	EPSD;PhosphoSitePlus	TCGA;COSMIC	56.683	Down-regulation
CAMK_CAMKL_AMPK_PRKAA1_ST	P13569	CFTR	Q13131	PRKAA1	S768	R765S	765	Missense	distal	-3	no	65.934	56.539	EPSD;PhosphoSitePlus	TCGA;COSMIC	56.683	Loss
CAMK_CAMKL_AMPK_PRKAA1_ST	P13569	CFTR	Q13131	PRKAA1	S768	R764Q	764	Missense	distal	-4	no	65.934	64.466	EPSD;PhosphoSitePlus	TCGA;COSMIC	56.683	Down-regulation
CAMK_CAMKL_AMPK_PRKAA1_ST	P13569	CFTR	Q13131	PRKAA1	S1248	G1247A	1247	Missense	proximal	-1	no	65.680	65.696	EPSD	TCGA;COSMIC	56.683	Up-regulation
CAMK_CAMKL_AMPK_PRKAA1_ST	P13569	CFTR	Q13131	PRKAA1	S1248	S1255L	1255	Missense	distal	7	no	65.680	65.722	EPSD	TCGA;COSMIC	56.683	Up-regulation
CAMK_CAMKL_AMPK_PRKAA1_ST	P13569	CFTR	Q13131	PRKAA1	S1248	L1253S	1253	Missense	distal	5	no	65.680	65.648	EPSD	TCGA;COSMIC	56.683	Down-regulation
CAMK_CAMKL_AMPK_PRKAA1_ST	P13569	CFTR	Q13131	PRKAA1	S1426	V1421E	1421	Missense	distal	-5	no	53.723	56.969	EPSD	TCGA;COSMIC	56.683	Gain
CAMK_CAMKL_AMPK_PRKAA1_ST	P13569	CFTR	Q13131	PRKAA1	S1455	S1456I	1456	Missense	proximal	1	no	60.208	58.629	EPSD	TCGA;COSMIC	56.683	Down-regulation
CAMK_CAMKL_AMPK_PRKAA1_ST	P13569	CFTR	Q13131	PRKAA1	S1455	S1460F	1460	Missense	distal	5	no	60.208	60.079	EPSD	TCGA;COSMIC	56.683	Down-regulation
CAMK_CAMKL_AMPK_PRKAA1_ST	P13569	CFTR	Q13131	PRKAA1	S1455	P1451S	1451	Missense	distal	-4	no	60.208	61.451	EPSD	TCGA;COSMIC	56.683	Up-regulation
CAMK_CAMKL_AMPK_PRKAA1_ST	P13569	CFTR	Q13131	PRKAA1	S1455	F1450V	1450	Missense	distal	-5	no	60.208	60.868	EPSD	TCGA;COSMIC	56.683	Up-regulation
CAMK_CAMKL_AMPK_PRKAA1_ST	P13569	CFTR	Q13131	PRKAA1	S1456	S1460F	1460	Missense	distal	4	no	55.860	58.253	EPSD	TCGA;COSMIC	56.683	Gain
CAMK_CAMKL_AMPK_PRKAA1_ST	P22460	KCNA5	Q13131	PRKAA1	S127	G128R	128	Missense	proximal	1	no	57.242	55.668	EPSD	TCGA;ICGC;COSMIC	56.683	Loss
CAMK_CAMKL_AMPK_PRKAA1_ST	P22460	KCNA5	Q13131	PRKAA1	S127	R130H	130	Missense	distal	3	no	57.242	53.674	EPSD	TCGA;ICGC;COSMIC	56.683	Loss
CAMK_CAMKL_AMPK_PRKAA1_ST	P22460	KCNA5	Q13131	PRKAA1	S127	G128W	128	Missense	proximal	1	no	57.242	56.273	EPSD	TCGA;ICGC;COSMIC	56.683	Loss
CAMK_CAMKL_AMPK_PRKAA1_ST	P22460	KCNA5	Q13131	PRKAA1	S127	T133M	133	Missense	distal	6	no	57.242	57.416	EPSD	TCGA;ICGC;COSMIC	56.683	Up-regulation
CAMK_CAMKL_AMPK_PRKAA1_ST	P22460	KCNA5	Q13131	PRKAA1	S127	R121H	121	Missense	distal	-6	no	57.242	55.709	EPSD	TCGA;ICGC;COSMIC	56.683	Loss
CAMK_CAMKL_AMPK_PRKAA1_ST	P22460	KCNA5	Q13131	PRKAA1	S127	T133R	133	Missense	distal	6	no	57.242	57.202	EPSD	TCGA;ICGC;COSMIC	56.683	Down-regulation
CAMK_CAMKL_AMPK_PRKAA1_ST	P22460	KCNA5	Q13131	PRKAA1	S557	R550T	550	Missense	distal	-7	no	59.359	58.502	EPSD	TCGA;ICGC;COSMIC	56.683	Down-regulation
CAMK_CAMKL_AMPK_PRKAA1_ST	P22460	KCNA5	Q13131	PRKAA1	S557	S562F	562	Missense	distal	5	no	59.359	59.230	EPSD	TCGA;ICGC;COSMIC	56.683	Down-regulation
CAMK_CAMKL_AMPK_PRKAA1_ST	P22460	KCNA5	Q13131	PRKAA1	S557	G558R	558	Missense	proximal	1	no	59.359	57.785	EPSD	TCGA;ICGC	56.683	Down-regulation
CAMK_CAMKL_AMPK_PRKAA1_ST	P22460	KCNA5	Q13131	PRKAA1	S557	G561E	561	Missense	distal	4	no	59.359	55.801	EPSD	TCGA;ICGC;COSMIC	56.683	Loss
CAMK_CAMKL_AMPK_PRKAA1_ST	P22460	KCNA5	Q13131	PRKAA1	S557	R554Q	554	Missense	distal	-3	no	59.359	51.415	EPSD	TCGA;ICGC;COSMIC	56.683	Loss
CAMK_CAMKL_AMPK_PRKAA1_ST	P22460	KCNA5	Q13131	PRKAA1	S575	R577Q	577	Missense	proximal	2	no	65.857	65.380	EPSD	TCGA;ICGC;COSMIC;GDSC;CCLE	56.683	Down-regulation
CAMK_CAMKL_AMPK_PRKAA1_ST	P22460	KCNA5	Q13131	PRKAA1	S575	P582L	582	Missense	distal	7	no	65.857	66.397	EPSD	TCGA;ICGC;COSMIC	56.683	Up-regulation
CAMK_CAMKL_AMPK_PRKAA1_ST	P22460	KCNA5	Q13131	PRKAA1	S575	G579S	579	Missense	distal	4	no	65.857	66.952	EPSD	TCGA;ICGC;COSMIC	56.683	Up-regulation
CAMK_CAMKL_AMPK_PRKAA1_ST	O43524	FOXO3	Q13131	PRKAA1	S75	D68Y	68	Missense	distal	-7	no	56.886	55.632	EPSD	TCGA;ICGC;COSMIC	56.683	Loss
CAMK_CAMKL_AMPK_PRKAA1_ST	O43524	FOXO3	Q13131	PRKAA1	S161	N159H	159	Missense	proximal	-2	no	58.083	54.782	EPSD	TCGA	56.683	Loss
CAMK_CAMKL_AMPK_PRKAA1_ST	O43524	FOXO3	Q13131	PRKAA1	S161	L165P	165	Missense	distal	4	no	58.083	51.343	EPSD	TCGA;ICGC;COSMIC	56.683	Loss
CAMK_CAMKL_AMPK_PRKAA1_ST	O43524	FOXO3	Q13131	PRKAA1	S215	S209F	209	Missense	distal	-6	no	61.885	61.988	EPSD	TCGA;ICGC	56.683	Up-regulation
CAMK_CAMKL_AMPK_PRKAA1_ST	O43524	FOXO3	Q13131	PRKAA1	S215	R222W	222	Missense	distal	7	no	61.885	62.110	EPSD	TCGA;ICGC;COSMIC;GDSC;CCLE	56.683	Up-regulation
CAMK_CAMKL_AMPK_PRKAA1_ST	O43524	FOXO3	Q13131	PRKAA1	S215	S209Y	209	Missense	distal	-6	no	61.885	59.387	EPSD	TCGA;ICGC;COSMIC	56.683	Down-regulation
CAMK_CAMKL_AMPK_PRKAA1_ST	O43524	FOXO3	Q13131	PRKAA1	S253	R248Q	248	Missense	distal	-5	no	63.963	58.281	EPSD	TCGA;ICGC;COSMIC	56.683	Down-regulation
CAMK_CAMKL_AMPK_PRKAA1_ST	O43524	FOXO3	Q13131	PRKAA1	S253	R250W	250	Missense	distal	-3	no	63.963	-29.037	EPSD	TCGA;ICGC;COSMIC	56.683	Loss
CAMK_CAMKL_AMPK_PRKAA1_ST	O43524	FOXO3	Q13131	PRKAA1	S253	R250Q	250	Missense	distal	-3	no	63.963	56.018	EPSD	TCGA;ICGC;COSMIC	56.683	Loss
CAMK_CAMKL_AMPK_PRKAA1_ST	O43524	FOXO3	Q13131	PRKAA1	T307	D308Y	308	Missense	proximal	1	no	54.426	57.581	EPSD	TCGA;ICGC;COSMIC	56.683	Gain
CAMK_CAMKL_AMPK_PRKAA1_ST	O43524	FOXO3	Q13131	PRKAA1	T313	R310C	310	Missense	distal	-3	no	69.035	54.887	EPSD	TCGA;ICGC;COSMIC	56.683	Loss
CAMK_CAMKL_AMPK_PRKAA1_ST	O43524	FOXO3	Q13131	PRKAA1	T313	D308Y	308	Missense	distal	-5	no	69.035	69.032	EPSD	TCGA;ICGC;COSMIC	56.683	Down-regulation
CAMK_CAMKL_AMPK_PRKAA1_ST	O43524	FOXO3	Q13131	PRKAA1	T313	S315F	315	Missense	proximal	2	no	69.035	68.742	EPSD	TCGA;ICGC;COSMIC	56.683	Down-regulation
CAMK_CAMKL_AMPK_PRKAA1_ST	O43524	FOXO3	Q13131	PRKAA1	T313	R312C	312	Missense	proximal	-1	no	69.035	69.181	EPSD	TCGA;ICGC;COSMIC	56.683	Up-regulation
CAMK_CAMKL_AMPK_PRKAA1_ST	O43524	FOXO3	Q13131	PRKAA1	S359	C362F	362	Missense	distal	3	no	57.355	57.978	EPSD	TCGA;ICGC;COSMIC	56.683	Up-regulation
CAMK_CAMKL_AMPK_PRKAA1_ST	O43524	FOXO3	Q13131	PRKAA1	S399	P397S	397	Missense	proximal	-2	no	57.857	57.308	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	56.683	Down-regulation
CAMK_CAMKL_AMPK_PRKAA1_ST	O43524	FOXO3	Q13131	PRKAA1	S399	P397L	397	Missense	proximal	-2	no	57.857	54.882	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	56.683	Loss
CAMK_CAMKL_AMPK_PRKAA1_ST	O43524	FOXO3	Q13131	PRKAA1	S399	D392G	392	Missense	distal	-7	no	57.857	59.161	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	56.683	Up-regulation
CAMK_CAMKL_AMPK_PRKAA1_ST	O43524	FOXO3	Q13131	PRKAA1	S399	S402L	402	Missense	distal	3	no	57.857	55.875	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	56.683	Loss
CAMK_CAMKL_AMPK_PRKAA1_ST	O43524	FOXO3	Q13131	PRKAA1	S413	S412C	412	Missense	proximal	-1	no	72.932	73.047	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	56.683	Up-regulation
CAMK_CAMKL_AMPK_PRKAA1_ST	O43524	FOXO3	Q13131	PRKAA1	S439	G436R	436	Missense	distal	-3	no	53.421	62.456	EPSD	TCGA;ICGC;COSMIC;GDSC;CCLE	56.683	Gain
CAMK_CAMKL_AMPK_PRKAA1_ST	O43524	FOXO3	Q13131	PRKAA1	S439	V434M	434	Missense	distal	-5	no	53.421	58.117	EPSD	TCGA;ICGC;COSMIC	56.683	Gain
CAMK_CAMKL_AMPK_PRKAA1_ST	O43524	FOXO3	Q13131	PRKAA1	S555	S560I	560	Missense	distal	5	no	67.996	67.959	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	56.683	Down-regulation
CAMK_CAMKL_AMPK_PRKAA1_ST	O43524	FOXO3	Q13131	PRKAA1	S555	S553Y	553	Missense	proximal	-2	no	67.996	66.434	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	56.683	Down-regulation
CAMK_CAMKL_AMPK_PRKAA1_ST	O43524	FOXO3	Q13131	PRKAA1	S564	S560I	560	Missense	distal	-4	no	61.248	58.449	EPSD	TCGA;ICGC;COSMIC	56.683	Down-regulation
CAMK_CAMKL_AMPK_PRKAA1_ST	O43524	FOXO3	Q13131	PRKAA1	S588	D585A	585	Missense	distal	-3	no	64.752	63.748	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	56.683	Down-regulation
CAMK_CAMKL_AMPK_PRKAA1_ST	O43524	FOXO3	Q13131	PRKAA1	S666	A665S	665	Missense	proximal	-1	no	58.441	58.419	EPSD	TCGA;ICGC;COSMIC	56.683	Down-regulation
CAMK_CAMKL_AMPK_PRKAA1_ST	O43524	FOXO3	Q13131	PRKAA1	S666	S669R	669	Missense	distal	3	no	58.441	57.791	EPSD	TCGA;ICGC	56.683	Down-regulation
CAMK_CAMKL_AMPK_PRKAA1_ST	P46527	CDKN1B	Q13131	PRKAA1	S83	K81R	81	Missense	proximal	-2	no	58.576	57.198	EPSD	TCGA;ICGC;COSMIC	56.683	Down-regulation
CAMK_CAMKL_AMPK_PRKAA1_ST	P46527	CDKN1B	Q13131	PRKAA1	S110	A103V	103	Missense	distal	-7	no	56.289	57.614	EPSD	TCGA;ICGC	56.683	Gain
CAMK_CAMKL_AMPK_PRKAA1_ST	P46527	CDKN1B	Q13131	PRKAA1	S140	E146K	146	Missense	distal	6	no	63.949	63.720	EPSD	TCGA;ICGC;COSMIC	56.683	Down-regulation
CAMK_CAMKL_AMPK_PRKAA1_ST	P46527	CDKN1B	Q13131	PRKAA1	T157	S161C	161	Missense	distal	4	no	57.685	37.937	EPSD	TCGA;ICGC;COSMIC	56.683	Loss
CAMK_CAMKL_AMPK_PRKAA1_ST	P46527	CDKN1B	Q13131	PRKAA1	T157	S161Y	161	Missense	distal	4	no	57.685	55.462	EPSD	TCGA;ICGC	56.683	Loss
CAMK_CAMKL_AMPK_PRKAA1_ST	P46527	CDKN1B	Q13131	PRKAA1	T157	G150E	150	Missense	distal	-7	no	57.685	56.479	EPSD	TCGA;ICGC;COSMIC	56.683	Loss
CAMK_CAMKL_AMPK_PRKAA1_ST	P08151	GLI1	Q13131	PRKAA1	S84	I85M	85	Missense	proximal	1	no	60.430	64.052	EPSD	TCGA;COSMIC	56.683	Up-regulation
CAMK_CAMKL_AMPK_PRKAA1_ST	P08151	GLI1	Q13131	PRKAA1	S84	R81L	81	Missense	distal	-3	no	60.430	50.464	EPSD	TCGA;COSMIC	56.683	Loss
CAMK_CAMKL_AMPK_PRKAA1_ST	P08151	GLI1	Q13131	PRKAA1	S84	S89L	89	Missense	distal	5	no	60.430	60.462	EPSD	TCGA;COSMIC	56.683	Up-regulation
CAMK_CAMKL_AMPK_PRKAA1_ST	P08151	GLI1	Q13131	PRKAA1	S84	S84P	84	Missense	central	0	yes	60.430	0.000	EPSD	TCGA;COSMIC	56.683	Loss
CAMK_CAMKL_AMPK_PRKAA1_ST	P08151	GLI1	Q13131	PRKAA1	S84	R81W	81	Missense	distal	-3	no	60.430	-32.570	EPSD	TCGA;COSMIC	56.683	Loss
CAMK_CAMKL_AMPK_PRKAA1_ST	P08151	GLI1	Q13131	PRKAA1	S84	R81Q	81	Missense	distal	-3	no	60.430	52.486	EPSD	TCGA;COSMIC	56.683	Loss
CAMK_CAMKL_AMPK_PRKAA1_ST	P08151	GLI1	Q13131	PRKAA1	S84	K79N	79	Missense	distal	-5	no	60.430	45.587	EPSD	TCGA;COSMIC	56.683	Loss
CAMK_CAMKL_AMPK_PRKAA1_ST	P08151	GLI1	Q13131	PRKAA1	S89	I85M	85	Missense	distal	-4	no	60.189	61.520	EPSD	TCGA;COSMIC	56.683	Up-regulation
CAMK_CAMKL_AMPK_PRKAA1_ST	P08151	GLI1	Q13131	PRKAA1	S89	S89L	89	Missense	central	0	yes	60.189	0.000	EPSD	TCGA;COSMIC	56.683	Loss
CAMK_CAMKL_AMPK_PRKAA1_ST	P08151	GLI1	Q13131	PRKAA1	S89	S84P	84	Missense	distal	-5	no	60.189	59.631	EPSD	TCGA;COSMIC	56.683	Down-regulation
CAMK_CAMKL_AMPK_PRKAA1_ST	P08151	GLI1	Q13131	PRKAA1	S89	D94Y	94	Missense	distal	5	no	60.189	60.170	EPSD	TCGA;COSMIC	56.683	Down-regulation
CAMK_CAMKL_AMPK_PRKAA1_ST	P08151	GLI1	Q13131	PRKAA1	S204	S200C	200	Missense	distal	-4	no	57.771	63.146	EPSD	TCGA;COSMIC	56.683	Up-regulation
CAMK_CAMKL_AMPK_PRKAA1_ST	P08151	GLI1	Q13131	PRKAA1	S204	D209Y	209	Missense	distal	5	no	57.771	57.752	EPSD	TCGA;COSMIC	56.683	Down-regulation
CAMK_CAMKL_AMPK_PRKAA1_ST	P08151	GLI1	Q13131	PRKAA1	S204	G197S	197	Missense	distal	-7	no	57.771	57.351	EPSD	TCGA;COSMIC	56.683	Down-regulation
CAMK_CAMKL_AMPK_PRKAA1_ST	P08151	GLI1	Q13131	PRKAA1	S204	G197D	197	Missense	distal	-7	no	57.771	56.466	EPSD	TCGA;COSMIC	56.683	Loss
CAMK_CAMKL_AMPK_PRKAA1_ST	P08151	GLI1	Q13131	PRKAA1	S204	P210S	210	Missense	distal	6	no	57.771	57.786	EPSD	TCGA;COSMIC	56.683	Up-regulation
CAMK_CAMKL_AMPK_PRKAA1_ST	P08151	GLI1	Q13131	PRKAA1	S204	Q208H	208	Missense	distal	4	no	57.771	58.853	EPSD	TCGA;COSMIC	56.683	Up-regulation
CAMK_CAMKL_AMPK_PRKAA1_ST	P08151	GLI1	Q13131	PRKAA1	S408	R405G	405	Missense	distal	-3	no	63.799	54.764	PhosphoSitePlus	TCGA;COSMIC	56.683	Loss
CAMK_CAMKL_AMPK_PRKAA1_ST	P08151	GLI1	Q13131	PRKAA1	S408	R405W	405	Missense	distal	-3	no	63.799	-29.201	PhosphoSitePlus	TCGA;COSMIC	56.683	Loss
CAMK_CAMKL_AMPK_PRKAA1_ST	P08151	GLI1	Q13131	PRKAA1	S538	R531L	531	Missense	distal	-7	no	58.830	57.398	EPSD	TCGA;COSMIC	56.683	Down-regulation
CAMK_CAMKL_AMPK_PRKAA1_ST	P08151	GLI1	Q13131	PRKAA1	S538	R541H	541	Missense	distal	3	no	58.830	55.262	EPSD	TCGA;COSMIC	56.683	Loss
CAMK_CAMKL_AMPK_PRKAA1_ST	P08151	GLI1	Q13131	PRKAA1	S538	R532H	532	Missense	distal	-6	no	58.830	57.297	EPSD	TCGA;COSMIC	56.683	Down-regulation
CAMK_CAMKL_AMPK_PRKAA1_ST	P08151	GLI1	Q13131	PRKAA1	S538	E540K	540	Missense	proximal	2	no	58.830	58.437	EPSD	TCGA;COSMIC	56.683	Down-regulation
CAMK_CAMKL_AMPK_PRKAA1_ST	P08151	GLI1	Q13131	PRKAA1	S538	R532S	532	Missense	distal	-6	no	58.830	58.359	EPSD	TCGA;COSMIC	56.683	Down-regulation
CAMK_CAMKL_AMPK_PRKAA1_ST	P08151	GLI1	Q13131	PRKAA1	S538	V537A	537	Missense	proximal	-1	no	58.830	58.922	EPSD	TCGA;COSMIC	56.683	Up-regulation
CAMK_CAMKL_AMPK_PRKAA1_ST	P08151	GLI1	Q13131	PRKAA1	S538	S543N	543	Missense	distal	5	no	58.830	58.793	EPSD	TCGA;COSMIC	56.683	Down-regulation
CAMK_CAMKL_AMPK_PRKAA1_ST	P08151	GLI1	Q13131	PRKAA1	S538	L539P	539	Missense	proximal	1	no	58.830	59.123	EPSD	TCGA	56.683	Up-regulation
CAMK_CAMKL_AMPK_PRKAA1_ST	P08151	GLI1	Q13131	PRKAA1	S545	R541H	541	Missense	distal	-4	no	73.952	70.565	EPSD	TCGA;COSMIC	56.683	Down-regulation
CAMK_CAMKL_AMPK_PRKAA1_ST	P08151	GLI1	Q13131	PRKAA1	S545	E540K	540	Missense	distal	-5	no	73.952	71.304	EPSD	TCGA;COSMIC	56.683	Down-regulation
CAMK_CAMKL_AMPK_PRKAA1_ST	P08151	GLI1	Q13131	PRKAA1	S545	S543N	543	Missense	proximal	-2	no	73.952	73.292	EPSD	TCGA;COSMIC	56.683	Down-regulation
CAMK_CAMKL_AMPK_PRKAA1_ST	P08151	GLI1	Q13131	PRKAA1	S545	L539P	539	Missense	distal	-6	no	73.952	73.991	EPSD	TCGA	56.683	Up-regulation
CAMK_CAMKL_AMPK_PRKAA1_ST	P08151	GLI1	Q13131	PRKAA1	S560	R557C	557	Missense	distal	-3	no	59.832	45.685	EPSD	TCGA;COSMIC	56.683	Loss
CAMK_CAMKL_AMPK_PRKAA1_ST	P08151	GLI1	Q13131	PRKAA1	S560	P564S	564	Missense	distal	4	no	59.832	59.984	EPSD	TCGA;COSMIC	56.683	Up-regulation
CAMK_CAMKL_AMPK_PRKAA1_ST	P08151	GLI1	Q13131	PRKAA1	S939	V936A	936	Missense	distal	-3	no	56.934	54.491	EPSD	TCGA;COSMIC	56.683	Loss
CAMK_CAMKL_AMPK_PRKAA1_ST	P08151	GLI1	Q13131	PRKAA1	S939	R940H	940	Missense	proximal	1	no	56.934	59.932	EPSD	TCGA;GDSC;CCLE	56.683	Up-regulation
CAMK_CAMKL_AMPK_PRKAA1_ST	P08151	GLI1	Q13131	PRKAA1	S1071	S1064F	1064	Missense	distal	-7	no	60.079	57.486	EPSD	TCGA;ICGC;COSMIC	56.683	Down-regulation
CAMK_CAMKL_AMPK_PRKAA1_ST	P08151	GLI1	Q13131	PRKAA1	S1071	P1077L	1077	Missense	distal	6	no	60.079	60.227	EPSD	TCGA;COSMIC	56.683	Up-regulation
CAMK_CAMKL_AMPK_PRKAA1_ST	P08151	GLI1	Q13131	PRKAA1	S1071	G1069S	1069	Missense	proximal	-2	no	60.079	63.383	EPSD	TCGA;COSMIC	56.683	Up-regulation
CAMK_CAMKL_AMPK_PRKAA1_ST	P08151	GLI1	Q13131	PRKAA1	S1071	S1070N	1070	Missense	proximal	-1	no	60.079	60.039	EPSD	TCGA	56.683	Down-regulation
CAMK_CAMKL_AMPK_PRKAA1_ST	P11908	PRPS2	Q13131	PRKAA1	S16	S11L	11	Missense	distal	-5	no	52.569	56.752	EPSD	TCGA;ICGC;COSMIC	56.683	Gain
CAMK_CAMKL_AMPK_PRKAA1_ST	P11908	PRPS2	Q13131	PRKAA1	S180	A175T	175	Missense	distal	-5	no	65.447	63.455	PhosphoSitePlus	TCGA;COSMIC	56.683	Down-regulation
CAMK_CAMKL_AMPK_PRKAA1_ST	Q9BZL4	PPP1R12C	Q13131	PRKAA1	S336	S336Y	336	Missense	central	0	yes	61.500	0.000	EPSD	TCGA;ICGC;COSMIC	56.683	Loss
CAMK_CAMKL_AMPK_PRKAA1_ST	Q9BZL4	PPP1R12C	Q13131	PRKAA1	S336	S336F	336	Missense	central	0	yes	61.500	0.000	EPSD	TCGA;ICGC;COSMIC	56.683	Loss
CAMK_CAMKL_AMPK_PRKAA1_ST	Q9BZL4	PPP1R12C	Q13131	PRKAA1	S344	R351H	351	Missense	distal	7	no	61.934	61.207	EPSD	TCGA;ICGC;COSMIC	56.683	Down-regulation
CAMK_CAMKL_AMPK_PRKAA1_ST	Q9BZL4	PPP1R12C	Q13131	PRKAA1	S355	R351H	351	Missense	distal	-4	no	58.388	55.001	EPSD	TCGA;ICGC;COSMIC	56.683	Loss
CAMK_CAMKL_AMPK_PRKAA1_ST	Q9BZL4	PPP1R12C	Q13131	PRKAA1	S355	S360C	360	Missense	distal	5	no	58.388	58.423	EPSD	TCGA;ICGC;COSMIC	56.683	Up-regulation
CAMK_CAMKL_AMPK_PRKAA1_ST	Q9BZL4	PPP1R12C	Q13131	PRKAA1	S355	S355F	355	Missense	central	0	yes	58.388	0.000	EPSD	TCGA;ICGC;COSMIC	56.683	Loss
CAMK_CAMKL_AMPK_PRKAA1_ST	Q9BZL4	PPP1R12C	Q13131	PRKAA1	S417	G421A	421	Missense	distal	4	no	55.526	58.679	EPSD	TCGA;ICGC;COSMIC	56.683	Gain
CAMK_CAMKL_AMPK_PRKAA1_ST	Q9BZL4	PPP1R12C	Q13131	PRKAA1	S427	G421A	421	Missense	distal	-6	no	61.052	62.215	EPSD	TCGA;ICGC;COSMIC	56.683	Up-regulation
CAMK_CAMKL_AMPK_PRKAA1_ST	Q9BZL4	PPP1R12C	Q13131	PRKAA1	S498	P505L	505	Missense	distal	7	no	63.767	64.307	EPSD	TCGA;ICGC;COSMIC;GDSC;CCLE	56.683	Up-regulation
CAMK_CAMKL_AMPK_PRKAA1_ST	Q9BZL4	PPP1R12C	Q13131	PRKAA1	S498	P505A	505	Missense	distal	7	no	63.767	64.393	EPSD	TCGA;ICGC;COSMIC	56.683	Up-regulation
CAMK_CAMKL_AMPK_PRKAA1_ST	Q9BZL4	PPP1R12C	Q13131	PRKAA1	S498	E496D	496	Missense	proximal	-2	no	63.767	63.192	EPSD	TCGA;ICGC	56.683	Down-regulation
CAMK_CAMKL_AMPK_PRKAA1_ST	Q9BZL4	PPP1R12C	Q13131	PRKAA1	S532	R527Q	527	Missense	distal	-5	no	66.150	60.467	EPSD	TCGA;ICGC	56.683	Down-regulation
CAMK_CAMKL_AMPK_PRKAA1_ST	Q9BZL4	PPP1R12C	Q13131	PRKAA1	S532	R538W	538	Missense	distal	6	no	66.150	65.659	EPSD	TCGA;ICGC;COSMIC	56.683	Down-regulation
CAMK_CAMKL_AMPK_PRKAA1_ST	Q9BZL4	PPP1R12C	Q13131	PRKAA1	S532	D539G	539	Missense	distal	7	no	66.150	67.318	EPSD	TCGA;ICGC;COSMIC	56.683	Up-regulation
CAMK_CAMKL_AMPK_PRKAA1_ST	Q9BZL4	PPP1R12C	Q13131	PRKAA1	S532	R529Q	529	Missense	distal	-3	no	66.150	58.205	EPSD	TCGA;ICGC	56.683	Down-regulation
CAMK_CAMKL_AMPK_PRKAA1_ST	Q9BZL4	PPP1R12C	Q13131	PRKAA1	S544	R538W	538	Missense	distal	-6	no	57.037	52.225	EPSD	TCGA;ICGC;COSMIC	56.683	Loss
CAMK_CAMKL_AMPK_PRKAA1_ST	Q9BZL4	PPP1R12C	Q13131	PRKAA1	S544	D539G	539	Missense	distal	-5	no	57.037	57.886	EPSD	TCGA;ICGC;COSMIC	56.683	Up-regulation
CAMK_CAMKL_AMPK_PRKAA1_ST	Q9BZL4	PPP1R12C	Q13131	PRKAA1	S544	R549H	549	Missense	distal	5	no	57.037	56.845	EPSD	TCGA;ICGC;COSMIC;GDSC;CCLE	56.683	Down-regulation
CAMK_CAMKL_AMPK_PRKAA1_ST	Q9BZL4	PPP1R12C	Q13131	PRKAA1	S559	R554H	554	Missense	distal	-5	no	63.273	57.892	EPSD	TCGA;ICGC;COSMIC	56.683	Down-regulation
CAMK_CAMKL_AMPK_PRKAA1_ST	Q9BZL4	PPP1R12C	Q13131	PRKAA1	S559	Q561P	561	Missense	proximal	2	no	63.273	64.199	EPSD	TCGA;ICGC;COSMIC	56.683	Up-regulation
CAMK_CAMKL_AMPK_PRKAA1_ST	Q9BZL4	PPP1R12C	Q13131	PRKAA1	S559	R558K	558	Missense	proximal	-1	no	63.273	63.199	EPSD	TCGA;ICGC;COSMIC	56.683	Down-regulation
CAMK_CAMKL_AMPK_PRKAA1_ST	Q9BZL4	PPP1R12C	Q13131	PRKAA1	S559	R557W	557	Missense	proximal	-2	no	63.273	60.934	EPSD	TCGA;ICGC	56.683	Down-regulation
CAMK_CAMKL_AMPK_PRKAA1_ST	Q9BZL4	PPP1R12C	Q13131	PRKAA1	S559	L565P	565	Missense	distal	6	no	63.273	63.124	EPSD	TCGA;ICGC;COSMIC	56.683	Down-regulation
CAMK_CAMKL_AMPK_PRKAA1_ST	Q9BZL4	PPP1R12C	Q13131	PRKAA1	S559	T564P	564	Missense	distal	5	no	63.273	63.266	EPSD	TCGA;ICGC	56.683	Down-regulation
CAMK_CAMKL_AMPK_PRKAA1_ST	Q9BZL4	PPP1R12C	Q13131	PRKAA1	S757	D762V	762	Missense	distal	5	no	66.004	65.843	EPSD	TCGA;ICGC;COSMIC	56.683	Down-regulation
CAMK_CAMKL_AMPK_PRKAA1_ST	Q9BZL4	PPP1R12C	Q13131	PRKAA1	S757	R760C	760	Missense	distal	3	no	66.004	64.823	EPSD	TCGA;ICGC;COSMIC;GDSC;CCLE	56.683	Down-regulation
CAMK_CAMKL_AMPK_PRKAA1_ST	Q6TCH7	PAQR3	Q13131	PRKAA1	S101	C108R	108	Missense	distal	7	no	57.349	57.316	EPSD	TCGA;ICGC;COSMIC	56.683	Down-regulation
CAMK_CAMKL_AMPK_PRKAA1_ST	Q6TCH7	PAQR3	Q13131	PRKAA1	S101	A100S	100	Missense	proximal	-1	no	57.349	57.327	EPSD	TCGA;ICGC;COSMIC	56.683	Down-regulation
CAMK_CAMKL_AMPK_PRKAA1_ST	P04637	TP53	Q13131	PRKAA1	S46	D48N	48	Missense	proximal	2	no	58.440	57.554	EPSD	TCGA;ICGC;COSMIC;GDSC;CCLE	56.683	Down-regulation
CAMK_CAMKL_AMPK_PRKAA1_ST	P04637	TP53	Q13131	PRKAA1	S99	P92S	92	Missense	distal	-7	no	54.806	57.073	EPSD	TCGA;ICGC	56.683	Gain
CAMK_CAMKL_AMPK_PRKAA1_ST	P04637	TP53	Q13131	PRKAA1	S106	G105C	105	Missense	proximal	-1	no	57.242	57.350	EPSD	TCGA;ICGC;COSMIC;GDSC	56.683	Up-regulation
CAMK_CAMKL_AMPK_PRKAA1_ST	P04637	TP53	Q13131	PRKAA1	S106	R110L	110	Missense	distal	4	no	57.242	62.724	EPSD	TCGA;ICGC;COSMIC;GDSC;CCLE	56.683	Up-regulation
CAMK_CAMKL_AMPK_PRKAA1_ST	P04637	TP53	Q13131	PRKAA1	S106	L111R	111	Missense	distal	5	no	57.242	57.245	EPSD	TCGA;ICGC;COSMIC	56.683	Up-regulation
CAMK_CAMKL_AMPK_PRKAA1_ST	P04637	TP53	Q13131	PRKAA1	S106	L111P	111	Missense	distal	5	no	57.242	57.249	EPSD	TCGA;ICGC;COSMIC	56.683	Up-regulation
CAMK_CAMKL_AMPK_PRKAA1_ST	P04637	TP53	Q13131	PRKAA1	S106	L111Q	111	Missense	distal	5	no	57.242	57.291	EPSD	TCGA;ICGC;COSMIC	56.683	Up-regulation
CAMK_CAMKL_AMPK_PRKAA1_ST	P04637	TP53	Q13131	PRKAA1	S106	Y107D	107	Missense	proximal	1	no	57.242	54.087	EPSD	TCGA;ICGC;COSMIC	56.683	Loss
CAMK_CAMKL_AMPK_PRKAA1_ST	P04637	TP53	Q13131	PRKAA1	S106	F113C	113	Missense	distal	7	no	57.242	57.957	EPSD	TCGA;ICGC;COSMIC;GDSC;CCLE	56.683	Up-regulation
CAMK_CAMKL_AMPK_PRKAA1_ST	P04637	TP53	Q13131	PRKAA1	S106	F113V	113	Missense	distal	7	no	57.242	56.220	EPSD	TCGA;ICGC;COSMIC;GDSC;CCLE	56.683	Loss
CAMK_CAMKL_AMPK_PRKAA1_ST	P04637	TP53	Q13131	PRKAA1	S106	R110C	110	Missense	distal	4	no	57.242	36.389	EPSD	TCGA;ICGC;COSMIC;GDSC;CCLE	56.683	Loss
CAMK_CAMKL_AMPK_PRKAA1_ST	P04637	TP53	Q13131	PRKAA1	S106	S106R	106	Missense	central	0	yes	57.242	0.000	EPSD	TCGA;ICGC;COSMIC;GDSC;CCLE	56.683	Loss
CAMK_CAMKL_AMPK_PRKAA1_ST	P04637	TP53	Q13131	PRKAA1	S106	F109S	109	Missense	distal	3	no	57.242	58.450	EPSD	TCGA;ICGC;COSMIC	56.683	Up-regulation
CAMK_CAMKL_AMPK_PRKAA1_ST	P04637	TP53	Q13131	PRKAA1	S106	G105R	105	Missense	proximal	-1	no	57.242	57.204	EPSD	TCGA;ICGC;COSMIC;CCLE	56.683	Down-regulation
CAMK_CAMKL_AMPK_PRKAA1_ST	P04637	TP53	Q13131	PRKAA1	S106	G105V	105	Missense	proximal	-1	no	57.242	57.167	EPSD	TCGA;ICGC;COSMIC	56.683	Down-regulation
CAMK_CAMKL_AMPK_PRKAA1_ST	P04637	TP53	Q13131	PRKAA1	S106	F109V	109	Missense	distal	3	no	57.242	59.347	EPSD	TCGA;ICGC;COSMIC	56.683	Up-regulation
CAMK_CAMKL_AMPK_PRKAA1_ST	P04637	TP53	Q13131	PRKAA1	S106	R110P	110	Missense	distal	4	no	57.242	55.984	EPSD	TCGA;ICGC;COSMIC;GDSC;CCLE	56.683	Loss
CAMK_CAMKL_AMPK_PRKAA1_ST	P04637	TP53	Q13131	PRKAA1	S106	G105D	105	Missense	proximal	-1	no	57.242	57.237	EPSD	TCGA;ICGC;COSMIC	56.683	Down-regulation
CAMK_CAMKL_AMPK_PRKAA1_ST	P04637	TP53	Q13131	PRKAA1	S106	F109C	109	Missense	distal	3	no	57.242	56.619	EPSD	TCGA;ICGC;COSMIC	56.683	Loss
CAMK_CAMKL_AMPK_PRKAA1_ST	P04637	TP53	Q13131	PRKAA1	S106	G105S	105	Missense	proximal	-1	no	57.242	57.236	EPSD	TCGA;ICGC;COSMIC	56.683	Down-regulation
CAMK_CAMKL_AMPK_PRKAA1_ST	P04637	TP53	Q13131	PRKAA1	S106	G108S	108	Missense	proximal	2	no	57.242	57.752	EPSD	TCGA;ICGC;COSMIC	56.683	Up-regulation
CAMK_CAMKL_AMPK_PRKAA1_ST	P04637	TP53	Q13131	PRKAA1	S106	F113L	113	Missense	distal	7	no	57.242	58.552	EPSD	TCGA;ICGC;COSMIC;GDSC;CCLE	56.683	Up-regulation
CAMK_CAMKL_AMPK_PRKAA1_ST	P04637	TP53	Q13131	PRKAA1	S269	R273C	273	Missense	distal	4	no	57.267	36.413	EPSD	TCGA;ICGC;COSMIC;GDSC;CCLE	56.683	Loss
CAMK_CAMKL_AMPK_PRKAA1_ST	P04637	TP53	Q13131	PRKAA1	S269	C275S	275	Missense	distal	6	no	57.267	57.043	EPSD	TCGA;ICGC;COSMIC	56.683	Down-regulation
CAMK_CAMKL_AMPK_PRKAA1_ST	P04637	TP53	Q13131	PRKAA1	S269	R273L	273	Missense	distal	4	no	57.267	62.749	EPSD	TCGA;ICGC;COSMIC;GDSC;CCLE	56.683	Up-regulation
CAMK_CAMKL_AMPK_PRKAA1_ST	P04637	TP53	Q13131	PRKAA1	S269	E271K	271	Missense	proximal	2	no	57.267	56.874	EPSD	TCGA;ICGC;COSMIC;GDSC;CCLE	56.683	Down-regulation
CAMK_CAMKL_AMPK_PRKAA1_ST	P04637	TP53	Q13131	PRKAA1	S269	C275Y	275	Missense	distal	6	no	57.267	57.130	EPSD	TCGA;ICGC;COSMIC;GDSC;CCLE	56.683	Down-regulation
CAMK_CAMKL_AMPK_PRKAA1_ST	P04637	TP53	Q13131	PRKAA1	S269	R273S	273	Missense	distal	4	no	57.267	56.161	EPSD	TCGA;ICGC;COSMIC	56.683	Loss
CAMK_CAMKL_AMPK_PRKAA1_ST	P04637	TP53	Q13131	PRKAA1	S269	E271Q	271	Missense	proximal	2	no	57.267	56.281	EPSD	TCGA;ICGC;COSMIC	56.683	Loss
CAMK_CAMKL_AMPK_PRKAA1_ST	P04637	TP53	Q13131	PRKAA1	S269	L265P	265	Missense	distal	-4	no	57.267	57.518	EPSD	TCGA;ICGC;COSMIC;GDSC;CCLE	56.683	Up-regulation
CAMK_CAMKL_AMPK_PRKAA1_ST	P04637	TP53	Q13131	PRKAA1	S269	V272M	272	Missense	distal	3	no	57.267	52.660	EPSD	TCGA;ICGC;COSMIC;GDSC;CCLE	56.683	Loss
CAMK_CAMKL_AMPK_PRKAA1_ST	P04637	TP53	Q13131	PRKAA1	S269	G266E	266	Missense	distal	-3	no	57.267	57.820	EPSD	TCGA;ICGC;COSMIC;GDSC;CCLE	56.683	Up-regulation
CAMK_CAMKL_AMPK_PRKAA1_ST	P04637	TP53	Q13131	PRKAA1	S269	R273P	273	Missense	distal	4	no	57.267	56.009	EPSD	TCGA;ICGC;COSMIC	56.683	Loss
CAMK_CAMKL_AMPK_PRKAA1_ST	P04637	TP53	Q13131	PRKAA1	S269	F270I	270	Missense	proximal	1	no	57.267	51.148	EPSD	TCGA;ICGC;COSMIC	56.683	Loss
CAMK_CAMKL_AMPK_PRKAA1_ST	P04637	TP53	Q13131	PRKAA1	S269	R273H	273	Missense	distal	4	no	57.267	54.266	EPSD	TCGA;ICGC;COSMIC;GDSC;CCLE	56.683	Loss
CAMK_CAMKL_AMPK_PRKAA1_ST	P04637	TP53	Q13131	PRKAA1	S269	A276P	276	Missense	distal	7	no	57.267	56.641	EPSD	TCGA;ICGC;COSMIC	56.683	Loss
CAMK_CAMKL_AMPK_PRKAA1_ST	P04637	TP53	Q13131	PRKAA1	S269	V272L	272	Missense	distal	3	no	57.267	54.388	EPSD	TCGA;ICGC;COSMIC;GDSC;CCLE	56.683	Loss
CAMK_CAMKL_AMPK_PRKAA1_ST	P04637	TP53	Q13131	PRKAA1	S269	V274D	274	Missense	distal	5	no	57.267	57.428	EPSD	TCGA;ICGC;COSMIC;CCLE	56.683	Up-regulation
CAMK_CAMKL_AMPK_PRKAA1_ST	P04637	TP53	Q13131	PRKAA1	S269	G266V	266	Missense	distal	-3	no	57.267	57.887	EPSD	TCGA;ICGC;COSMIC;GDSC;CCLE	56.683	Up-regulation
CAMK_CAMKL_AMPK_PRKAA1_ST	P04637	TP53	Q13131	PRKAA1	S269	R267L	267	Missense	proximal	-2	no	57.267	56.080	EPSD	TCGA;ICGC;COSMIC;GDSC;CCLE	56.683	Loss
CAMK_CAMKL_AMPK_PRKAA1_ST	P04637	TP53	Q13131	PRKAA1	S269	R267W	267	Missense	proximal	-2	no	57.267	54.928	EPSD	TCGA;ICGC;COSMIC;GDSC;CCLE	56.683	Loss
CAMK_CAMKL_AMPK_PRKAA1_ST	P04637	TP53	Q13131	PRKAA1	S269	R267Q	267	Missense	proximal	-2	no	57.267	57.729	EPSD	TCGA;ICGC;COSMIC;CCLE	56.683	Up-regulation
CAMK_CAMKL_AMPK_PRKAA1_ST	P04637	TP53	Q13131	PRKAA1	S269	C275F	275	Missense	distal	6	no	57.267	57.308	EPSD	TCGA;ICGC;COSMIC;GDSC;CCLE	56.683	Up-regulation
CAMK_CAMKL_AMPK_PRKAA1_ST	P04637	TP53	Q13131	PRKAA1	S269	V274G	274	Missense	distal	5	no	57.267	57.277	EPSD	TCGA;ICGC;COSMIC;CCLE	56.683	Up-regulation
CAMK_CAMKL_AMPK_PRKAA1_ST	P04637	TP53	Q13131	PRKAA1	S269	V274L	274	Missense	distal	5	no	57.267	57.353	EPSD	TCGA;ICGC;COSMIC	56.683	Up-regulation
CAMK_CAMKL_AMPK_PRKAA1_ST	P04637	TP53	Q13131	PRKAA1	S269	G266R	266	Missense	distal	-3	no	57.267	66.302	EPSD	TCGA;ICGC;COSMIC;GDSC;CCLE	56.683	Up-regulation
CAMK_CAMKL_AMPK_PRKAA1_ST	P04637	TP53	Q13131	PRKAA1	S269	R267P	267	Missense	proximal	-2	no	57.267	59.055	EPSD	TCGA;ICGC;COSMIC;GDSC;CCLE	56.683	Up-regulation
CAMK_CAMKL_AMPK_PRKAA1_ST	P04637	TP53	Q13131	PRKAA1	S269	A276D	276	Missense	distal	7	no	57.267	55.919	EPSD	TCGA;ICGC;COSMIC	56.683	Loss
CAMK_CAMKL_AMPK_PRKAA1_ST	P04637	TP53	Q13131	PRKAA1	S269	L265R	265	Missense	distal	-4	no	57.267	59.826	EPSD	TCGA;ICGC;COSMIC	56.683	Up-regulation
CAMK_CAMKL_AMPK_PRKAA1_ST	P04637	TP53	Q13131	PRKAA1	S269	R267G	267	Missense	proximal	-2	no	57.267	55.202	EPSD	TCGA;ICGC;COSMIC	56.683	Loss
CAMK_CAMKL_AMPK_PRKAA1_ST	P04637	TP53	Q13131	PRKAA1	S269	F270C	270	Missense	proximal	1	no	57.267	52.064	EPSD	TCGA;ICGC;COSMIC	56.683	Loss
CAMK_CAMKL_AMPK_PRKAA1_ST	P04637	TP53	Q13131	PRKAA1	S269	E271V	271	Missense	proximal	2	no	57.267	57.610	EPSD	TCGA;ICGC;COSMIC	56.683	Up-regulation
CAMK_CAMKL_AMPK_PRKAA1_ST	P04637	TP53	Q13131	PRKAA1	S269	G262V	262	Missense	distal	-7	no	57.267	55.469	EPSD	TCGA;ICGC;COSMIC;GDSC;CCLE	56.683	Loss
CAMK_CAMKL_AMPK_PRKAA1_ST	P04637	TP53	Q13131	PRKAA1	S269	V274F	274	Missense	distal	5	no	57.267	57.192	EPSD	TCGA;ICGC;COSMIC;GDSC;CCLE	56.683	Down-regulation
CAMK_CAMKL_AMPK_PRKAA1_ST	P04637	TP53	Q13131	PRKAA1	S269	F270S	270	Missense	proximal	1	no	57.267	52.727	EPSD	TCGA;ICGC;COSMIC	56.683	Loss
CAMK_CAMKL_AMPK_PRKAA1_ST	P04637	TP53	Q13131	PRKAA1	S269	C275R	275	Missense	distal	6	no	57.267	56.936	EPSD	TCGA;ICGC;COSMIC	56.683	Down-regulation
CAMK_CAMKL_AMPK_PRKAA1_ST	P04637	TP53	Q13131	PRKAA1	S269	C275G	275	Missense	distal	6	no	57.267	56.815	EPSD	TCGA;ICGC;COSMIC;GDSC;CCLE	56.683	Down-regulation
CAMK_CAMKL_AMPK_PRKAA1_ST	P04637	TP53	Q13131	PRKAA1	S269	A276G	276	Missense	distal	7	no	57.267	57.088	EPSD	TCGA;ICGC;COSMIC	56.683	Down-regulation
CAMK_CAMKL_AMPK_PRKAA1_ST	P04637	TP53	Q13131	PRKAA1	S269	V272G	272	Missense	distal	3	no	57.267	57.572	EPSD	TCGA;ICGC;COSMIC	56.683	Up-regulation
CAMK_CAMKL_AMPK_PRKAA1_ST	P04637	TP53	Q13131	PRKAA1	S269	R273G	273	Missense	distal	4	no	57.267	55.065	EPSD	TCGA;ICGC;COSMIC	56.683	Loss
CAMK_CAMKL_AMPK_PRKAA1_ST	P04637	TP53	Q13131	PRKAA1	S269	F270V	270	Missense	proximal	1	no	57.267	52.591	EPSD	TCGA;ICGC;COSMIC	56.683	Loss
CAMK_CAMKL_AMPK_PRKAA1_ST	P04637	TP53	Q13131	PRKAA1	S269	C275W	275	Missense	distal	6	no	57.267	56.446	EPSD	TCGA;ICGC;COSMIC	56.683	Loss
CAMK_CAMKL_AMPK_PRKAA1_ST	P04637	TP53	Q13131	PRKAA1	S269	V272A	272	Missense	distal	3	no	57.267	52.391	EPSD	TCGA;ICGC;COSMIC	56.683	Loss
CAMK_CAMKL_AMPK_PRKAA1_ST	P04637	TP53	Q13131	PRKAA1	S269	F270L	270	Missense	proximal	1	no	57.267	51.801	EPSD	TCGA;ICGC;COSMIC	56.683	Loss
CAMK_CAMKL_AMPK_PRKAA1_ST	P04637	TP53	Q13131	PRKAA1	S378	S376C	376	Missense	proximal	-2	no	56.911	48.561	EPSD	TCGA;ICGC;COSMIC	56.683	Loss
CAMK_CAMKL_AMPK_PRKAA1_ST	P04637	TP53	Q13131	PRKAA1	S378	Q375K	375	Missense	distal	-3	no	56.911	60.215	EPSD	TCGA;ICGC;COSMIC	56.683	Up-regulation
CAMK_CAMKL_AMPK_PRKAA1_ST	P00533	EGFR	Q13131	PRKAA1	S457	S464P	464	Missense	distal	7	no	59.280	58.782	EPSD	TCGA;COSMIC	56.683	Down-regulation
CAMK_CAMKL_AMPK_PRKAA1_ST	P00533	EGFR	Q13131	PRKAA1	S695	P699L	699	Missense	distal	4	no	51.177	57.916	EPSD	TCGA;COSMIC	56.683	Gain
CAMK_CAMKL_AMPK_PRKAA1_ST	P00533	EGFR	Q13131	PRKAA1	S720	G724S	724	Missense	distal	4	no	57.037	58.133	EPSD	TCGA;COSMIC	56.683	Up-regulation
CAMK_CAMKL_AMPK_PRKAA1_ST	P00533	EGFR	Q13131	PRKAA1	S720	G719D	719	Missense	proximal	-1	no	57.037	57.032	EPSD	TCGA;COSMIC	56.683	Down-regulation
CAMK_CAMKL_AMPK_PRKAA1_ST	P00533	EGFR	Q13131	PRKAA1	S720	G719C	719	Missense	proximal	-1	no	57.037	57.146	EPSD	TCGA;COSMIC	56.683	Up-regulation
CAMK_CAMKL_AMPK_PRKAA1_ST	P00533	EGFR	Q13131	PRKAA1	S720	G719A	719	Missense	proximal	-1	no	57.037	57.053	EPSD	TCGA;COSMIC	56.683	Up-regulation
CAMK_CAMKL_AMPK_PRKAA1_ST	P00533	EGFR	Q13131	PRKAA1	S720	S720C	720	Missense	central	0	yes	57.037	0.000	EPSD	TCGA;COSMIC	56.683	Loss
CAMK_CAMKL_AMPK_PRKAA1_ST	P00533	EGFR	Q13131	PRKAA1	S752	I759N	759	Missense	distal	7	no	59.697	61.090	EPSD	TCGA;COSMIC	56.683	Up-regulation
CAMK_CAMKL_AMPK_PRKAA1_ST	P00533	EGFR	Q13131	PRKAA1	S752	K754E	754	Missense	proximal	2	no	59.697	60.090	EPSD	TCGA;COSMIC	56.683	Up-regulation
CAMK_CAMKL_AMPK_PRKAA1_ST	P00533	EGFR	Q13131	PRKAA1	S752	K754I	754	Missense	proximal	2	no	59.697	58.874	EPSD	TCGA;COSMIC	56.683	Down-regulation
CAMK_CAMKL_AMPK_PRKAA1_ST	P00533	EGFR	Q13131	PRKAA1	S752	P753L	753	Missense	proximal	1	no	59.697	59.404	EPSD	TCGA;COSMIC	56.683	Down-regulation
CAMK_CAMKL_AMPK_PRKAA1_ST	P00533	EGFR	Q13131	PRKAA1	S752	P753S	753	Missense	proximal	1	no	59.697	60.329	EPSD	TCGA;COSMIC;GDSC;CCLE	56.683	Up-regulation
CAMK_CAMKL_AMPK_PRKAA1_ST	P00533	EGFR	Q13131	PRKAA1	T892	H893Y	893	Missense	proximal	1	no	58.549	58.854	PhosphoSitePlus	TCGA;COSMIC	56.683	Up-regulation
CAMK_CAMKL_AMPK_PRKAA1_ST	P00533	EGFR	Q13131	PRKAA1	T1029	T1032S	1032	Missense	distal	3	no	56.218	57.282	EPSD	TCGA;COSMIC	56.683	Gain
CAMK_CAMKL_AMPK_PRKAA1_ST	P00533	EGFR	Q13131	PRKAA1	T1041	S1042N	1042	Missense	proximal	1	no	58.602	57.748	EPSD	TCGA;COSMIC	56.683	Down-regulation
CAMK_CAMKL_AMPK_PRKAA1_ST	P00533	EGFR	Q13131	PRKAA1	T1046	D1051N	1051	Missense	distal	5	no	58.346	58.202	EPSD	TCGA;COSMIC	56.683	Down-regulation
CAMK_CAMKL_AMPK_PRKAA1_ST	P00533	EGFR	Q13131	PRKAA1	T1046	S1042N	1042	Missense	distal	-4	no	58.346	53.546	EPSD	TCGA;COSMIC	56.683	Loss
CAMK_CAMKL_AMPK_PRKAA1_ST	P00533	EGFR	Q13131	PRKAA1	T1046	R1052I	1052	Missense	distal	6	no	58.346	58.130	EPSD	TCGA;COSMIC	56.683	Down-regulation
CAMK_CAMKL_AMPK_PRKAA1_ST	P00533	EGFR	Q13131	PRKAA1	T1150	D1152N	1152	Missense	proximal	2	no	66.138	65.252	EPSD	TCGA;ICGC;COSMIC	56.683	Down-regulation
CAMK_CAMKL_AMPK_PRKAA1_ST	P00533	EGFR	Q13131	PRKAA1	T1150	F1151L	1151	Missense	proximal	1	no	66.138	60.673	EPSD	TCGA;ICGC;COSMIC	56.683	Down-regulation
CAMK_CAMKL_AMPK_PRKAA1_ST	P00533	EGFR	Q13131	PRKAA1	T1150	V1147A	1147	Missense	distal	-3	no	66.138	63.696	EPSD	TCGA;ICGC	56.683	Down-regulation
CAMK_CAMKL_AMPK_PRKAA1_ST	P00533	EGFR	Q13131	PRKAA1	S1166	S1162C	1162	Missense	distal	-4	no	54.489	59.864	EPSD	TCGA;ICGC;COSMIC	56.683	Gain
CAMK_CAMKL_AMPK_PRKAA1_ST	P00533	EGFR	Q13131	PRKAA1	S1166	L1167M	1167	Missense	proximal	1	no	54.489	57.457	EPSD	TCGA;ICGC;COSMIC	56.683	Gain
CAMK_CAMKL_AMPK_PRKAA1_ST	P00533	EGFR	Q13131	PRKAA1	S1204	A1201V	1201	Missense	distal	-3	no	62.597	65.039	EPSD	TCGA;ICGC;COSMIC	56.683	Up-regulation
CAMK_CAMKL_AMPK_PRKAA1_ST	Q92538	GBF1	Q13131	PRKAA1	T78	E75K	75	Missense	distal	-3	no	57.615	61.456	EPSD	TCGA;ICGC;COSMIC	56.683	Up-regulation
CAMK_CAMKL_AMPK_PRKAA1_ST	Q92538	GBF1	Q13131	PRKAA1	T78	I81F	81	Missense	distal	3	no	57.615	58.784	EPSD	TCGA;ICGC;COSMIC	56.683	Up-regulation
CAMK_CAMKL_AMPK_PRKAA1_ST	Q92538	GBF1	Q13131	PRKAA1	T82	E75K	75	Missense	distal	-7	no	55.747	57.140	EPSD	TCGA;ICGC;COSMIC	56.683	Gain
CAMK_CAMKL_AMPK_PRKAA1_ST	Q92538	GBF1	Q13131	PRKAA1	S314	P315S	315	Missense	proximal	1	no	64.829	65.462	EPSD	TCGA;ICGC;COSMIC	56.683	Up-regulation
CAMK_CAMKL_AMPK_PRKAA1_ST	Q92538	GBF1	Q13131	PRKAA1	S325	E322Q	322	Missense	distal	-3	no	56.706	57.243	EPSD	TCGA;ICGC;COSMIC	56.683	Up-regulation
CAMK_CAMKL_AMPK_PRKAA1_ST	Q92538	GBF1	Q13131	PRKAA1	S349	S347L	347	Missense	proximal	-2	no	57.047	54.621	EPSD	TCGA;ICGC;COSMIC	56.683	Loss
CAMK_CAMKL_AMPK_PRKAA1_ST	Q92538	GBF1	Q13131	PRKAA1	S352	S347L	347	Missense	distal	-5	no	53.959	58.141	EPSD	TCGA;ICGC;COSMIC	56.683	Gain
CAMK_CAMKL_AMPK_PRKAA1_ST	Q92538	GBF1	Q13131	PRKAA1	S371	V378I	378	Missense	distal	7	no	55.669	56.867	EPSD	TCGA;ICGC;COSMIC	56.683	Gain
CAMK_CAMKL_AMPK_PRKAA1_ST	Q92538	GBF1	Q13131	PRKAA1	S670	A672G	672	Missense	proximal	2	no	57.868	57.559	EPSD	TCGA;ICGC;COSMIC	56.683	Down-regulation
CAMK_CAMKL_AMPK_PRKAA1_ST	Q92538	GBF1	Q13131	PRKAA1	S1298	P1292S	1292	Missense	distal	-6	no	59.577	59.227	EPSD	TCGA;ICGC;COSMIC	56.683	Down-regulation
CAMK_CAMKL_AMPK_PRKAA1_ST	Q92538	GBF1	Q13131	PRKAA1	S1304	V1310M	1310	Missense	distal	6	no	57.444	57.663	EPSD	TCGA;ICGC;COSMIC	56.683	Up-regulation
CAMK_CAMKL_AMPK_PRKAA1_ST	Q92538	GBF1	Q13131	PRKAA1	S1304	N1308I	1308	Missense	distal	4	no	57.444	62.426	EPSD	TCGA;ICGC;COSMIC	56.683	Up-regulation
CAMK_CAMKL_AMPK_PRKAA1_ST	Q92538	GBF1	Q13131	PRKAA1	T1317	V1310M	1310	Missense	distal	-7	no	58.757	60.562	EPSD	TCGA;ICGC;COSMIC	56.683	Up-regulation
CAMK_CAMKL_AMPK_PRKAA1_ST	Q92538	GBF1	Q13131	PRKAA1	T1337	G1330S	1330	Missense	distal	-7	no	65.333	64.913	PhosphoSitePlus	TCGA;ICGC;COSMIC	56.683	Down-regulation
CAMK_CAMKL_AMPK_PRKAA1_ST	Q92538	GBF1	Q13131	PRKAA1	S1444	R1448P	1448	Missense	distal	4	no	59.605	58.347	EPSD	TCGA;ICGC;COSMIC	56.683	Down-regulation
CAMK_CAMKL_AMPK_PRKAA1_ST	Q92538	GBF1	Q13131	PRKAA1	S1453	R1448P	1448	Missense	distal	-5	no	57.301	53.737	EPSD	TCGA;ICGC;COSMIC	56.683	Loss
CAMK_CAMKL_AMPK_PRKAA1_ST	Q92538	GBF1	Q13131	PRKAA1	T1464	R1471Q	1471	Missense	distal	7	no	55.945	57.309	EPSD	TCGA;ICGC;COSMIC	56.683	Gain
CAMK_CAMKL_AMPK_PRKAA1_ST	Q92538	GBF1	Q13131	PRKAA1	S1465	R1471Q	1471	Missense	distal	6	no	59.588	60.018	EPSD	TCGA;ICGC;COSMIC	56.683	Up-regulation
CAMK_CAMKL_AMPK_PRKAA1_ST	Q92538	GBF1	Q13131	PRKAA1	S1839	E1836K	1836	Missense	distal	-3	no	54.556	58.397	EPSD	TCGA;ICGC;COSMIC;CCLE	56.683	Gain
CAMK_CAMKL_AMPK_PRKAA1_ST	P60891	PRPS1	Q13131	PRKAA1	S180	L185P	185	Missense	distal	5	no	66.721	66.728	PhosphoSitePlus	TCGA;COSMIC	56.683	Up-regulation
CAMK_CAMKL_AMPK_PRKAA1_ST	P60891	PRPS1	Q13131	PRKAA1	S180	S180Y	180	Missense	central	0	yes	66.721	0.000	PhosphoSitePlus	TCGA;COSMIC	56.683	Loss
CAMK_CAMKL_AMPK_PRKAA1_ST	P60891	PRPS1	Q13131	PRKAA1	S180	T179A	179	Missense	proximal	-1	no	66.721	66.800	PhosphoSitePlus	TCGA	56.683	Up-regulation
CAMK_CAMKL_AMPK_PRKAA1_ST	P19429	TNNI3	Q13131	PRKAA1	S23	I19T	19	Missense	distal	-4	no	64.699	66.242	PhosphoSitePlus;EPSD	TCGA;ICGC;COSMIC	56.683	Up-regulation
CAMK_CAMKL_AMPK_PRKAA1_ST	P19429	TNNI3	Q13131	PRKAA1	S23	Y29H	29	Missense	distal	6	no	64.699	64.611	PhosphoSitePlus;EPSD	TCGA;ICGC;COSMIC	56.683	Down-regulation
CAMK_CAMKL_AMPK_PRKAA1_ST	P19429	TNNI3	Q13131	PRKAA1	S23	R21C	21	Missense	proximal	-2	no	64.699	57.588	PhosphoSitePlus;EPSD	TCGA	56.683	Down-regulation
CAMK_CAMKL_AMPK_PRKAA1_ST	P19429	TNNI3	Q13131	PRKAA1	S23	R22H	22	Missense	proximal	-1	no	64.699	64.719	PhosphoSitePlus;EPSD	TCGA;ICGC	56.683	Up-regulation
CAMK_CAMKL_AMPK_PRKAA1_ST	P19429	TNNI3	Q13131	PRKAA1	S24	I19T	19	Missense	distal	-5	no	67.603	61.361	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	56.683	Down-regulation
CAMK_CAMKL_AMPK_PRKAA1_ST	P19429	TNNI3	Q13131	PRKAA1	S24	Y29H	29	Missense	distal	5	no	67.603	67.357	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	56.683	Down-regulation
CAMK_CAMKL_AMPK_PRKAA1_ST	P19429	TNNI3	Q13131	PRKAA1	S24	R21C	21	Missense	distal	-3	no	67.603	53.456	EPSD;PhosphoSitePlus	TCGA	56.683	Loss
CAMK_CAMKL_AMPK_PRKAA1_ST	P19429	TNNI3	Q13131	PRKAA1	S24	R22H	22	Missense	proximal	-2	no	67.603	64.882	EPSD;PhosphoSitePlus	TCGA;ICGC	56.683	Down-regulation
CAMK_CAMKL_AMPK_PRKAA1_ST	P19429	TNNI3	Q13131	PRKAA1	T119	K117R	117	Missense	proximal	-2	no	58.629	57.251	EPSD	TCGA;COSMIC	56.683	Down-regulation
CAMK_CAMKL_AMPK_PRKAA1_ST	P19429	TNNI3	Q13131	PRKAA1	T119	E124K	124	Missense	distal	5	no	58.629	58.651	EPSD	TCGA;COSMIC	56.683	Up-regulation
CAMK_CAMKL_AMPK_PRKAA1_ST	P19429	TNNI3	Q13131	PRKAA1	S150	A153V	153	Missense	distal	3	no	59.336	64.212	EPSD;PhosphoSitePlus	TCGA	56.683	Up-regulation
CAMK_CAMKL_AMPK_PRKAA1_ST	P19429	TNNI3	Q13131	PRKAA1	S150	R145Q	145	Missense	distal	-5	no	59.336	53.654	EPSD;PhosphoSitePlus	TCGA;COSMIC;GDSC;CCLE	56.683	Loss
CAMK_CAMKL_AMPK_PRKAA1_ST	Q14457	BECN1	Q13131	PRKAA1	S90	P84L	84	Missense	distal	-6	no	59.533	59.494	EPSD	TCGA;ICGC;COSMIC	56.683	Down-regulation
CAMK_CAMKL_AMPK_PRKAA1_ST	Q14457	BECN1	Q13131	PRKAA1	S96	T98P	98	Missense	proximal	2	no	58.267	58.564	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	56.683	Up-regulation
CAMK_CAMKL_AMPK_PRKAA1_ST	Q14457	BECN1	Q13131	PRKAA1	S104	T98P	98	Missense	distal	-6	no	57.919	57.803	EPSD	TCGA;ICGC;COSMIC	56.683	Down-regulation
CAMK_CAMKL_AMPK_PRKAA1_ST	Q14457	BECN1	Q13131	PRKAA1	T108	R114Q	114	Missense	distal	6	no	59.691	60.120	EPSD	TCGA;ICGC;COSMIC	56.683	Up-regulation
CAMK_CAMKL_AMPK_PRKAA1_ST	Q14457	BECN1	Q13131	PRKAA1	T388	Y394C	394	Missense	distal	6	no	58.403	58.540	EPSD;PhosphoSitePlus	TCGA	56.683	Up-regulation
CAMK_CAMKL_AMPK_PRKAA1_ST	Q14457	BECN1	Q13131	PRKAA1	T388	E384Q	384	Missense	distal	-4	no	58.403	56.989	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	56.683	Down-regulation
CAMK_CAMKL_AMPK_PRKAA1_ST	Q14457	BECN1	Q13131	PRKAA1	T388	E387K	387	Missense	proximal	-1	no	58.403	58.378	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	56.683	Down-regulation
CAMK_CAMKL_AMPK_PRKAA1_ST	Q8N122	RPTOR	Q13131	PRKAA1	S721	S719F	719	Missense	proximal	-2	no	59.616	57.418	EPSD	TCGA;ICGC;COSMIC	56.683	Down-regulation
CAMK_CAMKL_AMPK_PRKAA1_ST	Q8N122	RPTOR	Q13131	PRKAA1	S721	Y723C	723	Missense	proximal	2	no	59.616	58.787	EPSD	TCGA;COSMIC	56.683	Down-regulation
CAMK_CAMKL_AMPK_PRKAA1_ST	Q8N122	RPTOR	Q13131	PRKAA1	S721	G724E	724	Missense	distal	3	no	59.616	57.445	EPSD	TCGA;COSMIC	56.683	Down-regulation
CAMK_CAMKL_AMPK_PRKAA1_ST	Q8N122	RPTOR	Q13131	PRKAA1	S722	S719F	719	Missense	distal	-3	no	64.569	64.717	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	56.683	Up-regulation
CAMK_CAMKL_AMPK_PRKAA1_ST	Q8N122	RPTOR	Q13131	PRKAA1	S722	Y723C	723	Missense	proximal	1	no	64.569	61.590	EPSD;PhosphoSitePlus	TCGA;COSMIC	56.683	Down-regulation
CAMK_CAMKL_AMPK_PRKAA1_ST	Q8N122	RPTOR	Q13131	PRKAA1	S722	G724E	724	Missense	proximal	2	no	64.569	65.681	EPSD;PhosphoSitePlus	TCGA;COSMIC	56.683	Up-regulation
CAMK_CAMKL_AMPK_PRKAA1_ST	Q8N122	RPTOR	Q13131	PRKAA1	T731	G724E	724	Missense	distal	-7	no	59.290	58.084	EPSD	TCGA;COSMIC	56.683	Down-regulation
CAMK_CAMKL_AMPK_PRKAA1_ST	Q13621	SLC12A1	Q13131	PRKAA1	S130	P124H	124	Missense	distal	-6	no	62.602	61.190	PhosphoSitePlus	TCGA;ICGC;COSMIC	56.683	Down-regulation
CAMK_CAMKL_AMPK_PRKAA1_ST	Q13621	SLC12A1	Q13131	PRKAA1	S130	R128Q	128	Missense	proximal	-2	no	62.602	63.065	PhosphoSitePlus	TCGA;ICGC;COSMIC	56.683	Up-regulation
CAMK_CAMKL_AMPK_PRKAA1_ST	Q13621	SLC12A1	Q13131	PRKAA1	S130	L131M	131	Missense	proximal	1	no	62.602	65.571	PhosphoSitePlus	TCGA;ICGC;COSMIC	56.683	Up-regulation
CAMK_CAMKL_AMPK_PRKAA1_ST	Q13621	SLC12A1	Q13131	PRKAA1	S885	H887Y	887	Missense	proximal	2	no	56.974	56.117	EPSD	TCGA;ICGC;COSMIC	56.683	Loss
CAMK_CAMKL_AMPK_PRKAA1_ST	Q13621	SLC12A1	Q13131	PRKAA1	S885	V888A	888	Missense	distal	3	no	56.974	52.097	EPSD	TCGA;ICGC	56.683	Loss
CAMK_CAMKL_AMPK_PRKAA1_ST	Q13621	SLC12A1	Q13131	PRKAA1	S1003	R999C	999	Missense	distal	-4	no	56.970	61.281	EPSD	TCGA;ICGC;COSMIC	56.683	Up-regulation
CAMK_CAMKL_AMPK_PRKAA1_ST	O75925	PIAS1	Q13131	PRKAA1	T71	S76F	76	Missense	distal	5	no	59.434	59.305	EPSD	TCGA;ICGC;COSMIC	56.683	Down-regulation
CAMK_CAMKL_AMPK_PRKAA1_ST	O75925	PIAS1	Q13131	PRKAA1	T71	D74N	74	Missense	distal	3	no	59.434	60.687	EPSD	TCGA;ICGC;COSMIC	56.683	Up-regulation
CAMK_CAMKL_AMPK_PRKAA1_ST	O75925	PIAS1	Q13131	PRKAA1	T71	M70V	70	Missense	proximal	-1	no	59.434	59.347	EPSD	TCGA	56.683	Down-regulation
CAMK_CAMKL_AMPK_PRKAA1_ST	O75925	PIAS1	Q13131	PRKAA1	S82	S76F	76	Missense	distal	-6	no	69.186	69.289	EPSD	TCGA;ICGC;COSMIC	56.683	Up-regulation
CAMK_CAMKL_AMPK_PRKAA1_ST	O75925	PIAS1	Q13131	PRKAA1	S155	N160S	160	Missense	distal	5	no	58.073	58.110	EPSD	TCGA;ICGC;COSMIC	56.683	Up-regulation
CAMK_CAMKL_AMPK_PRKAA1_ST	O75925	PIAS1	Q13131	PRKAA1	S155	D159N	159	Missense	distal	4	no	58.073	57.340	EPSD	TCGA	56.683	Down-regulation
CAMK_CAMKL_AMPK_PRKAA1_ST	O75925	PIAS1	Q13131	PRKAA1	S254	T253I	253	Missense	proximal	-1	no	58.649	58.720	EPSD	TCGA;ICGC;COSMIC	56.683	Up-regulation
CAMK_CAMKL_AMPK_PRKAA1_ST	O75925	PIAS1	Q13131	PRKAA1	S254	V256A	256	Missense	proximal	2	no	58.649	57.503	EPSD	TCGA;ICGC	56.683	Down-regulation
CAMK_CAMKL_AMPK_PRKAA1_ST	O75925	PIAS1	Q13131	PRKAA1	S254	R248Q	248	Missense	distal	-6	no	58.649	59.007	EPSD	TCGA;ICGC;COSMIC	56.683	Up-regulation
CAMK_CAMKL_AMPK_PRKAA1_ST	O75925	PIAS1	Q13131	PRKAA1	T261	V256A	256	Missense	distal	-5	no	60.298	61.490	EPSD	TCGA;ICGC	56.683	Up-regulation
CAMK_CAMKL_AMPK_PRKAA1_ST	O75925	PIAS1	Q13131	PRKAA1	S289	L294F	294	Missense	distal	5	no	64.633	64.472	EPSD	TCGA;ICGC;COSMIC	56.683	Down-regulation
CAMK_CAMKL_AMPK_PRKAA1_ST	O75925	PIAS1	Q13131	PRKAA1	S476	E473D	473	Missense	distal	-3	no	58.365	56.994	EPSD	TCGA;ICGC;COSMIC	56.683	Down-regulation
CAMK_CAMKL_AMPK_PRKAA1_ST	O75925	PIAS1	Q13131	PRKAA1	S476	P475S	475	Missense	proximal	-1	no	58.365	58.410	EPSD	TCGA;ICGC;COSMIC	56.683	Up-regulation
CAMK_CAMKL_AMPK_PRKAA1_ST	O75925	PIAS1	Q13131	PRKAA1	S485	P486S	486	Missense	proximal	1	no	62.320	62.953	EPSD	TCGA;ICGC;COSMIC	56.683	Up-regulation
CAMK_CAMKL_AMPK_PRKAA1_ST	O75925	PIAS1	Q13131	PRKAA1	S485	N491H	491	Missense	distal	6	no	62.320	62.436	EPSD	TCGA;ICGC;COSMIC	56.683	Up-regulation
CAMK_CAMKL_AMPK_PRKAA1_ST	O75925	PIAS1	Q13131	PRKAA1	S510	S510R	510	Missense	central	0	yes	64.495	0.000	PhosphoSitePlus	TCGA;ICGC	56.683	Loss
CAMK_CAMKL_AMPK_PRKAA1_ST	O75925	PIAS1	Q13131	PRKAA1	S510	P504L	504	Missense	distal	-6	no	64.495	64.456	PhosphoSitePlus	TCGA;ICGC;COSMIC	56.683	Down-regulation
CAMK_CAMKL_AMPK_PRKAA1_ST	P41235	HNF4A	Q13131	PRKAA1	S138	D135N	135	Missense	distal	-3	no	53.552	57.469	EPSD	TCGA;ICGC;COSMIC	56.683	Gain
CAMK_CAMKL_AMPK_PRKAA1_ST	P41235	HNF4A	Q13131	PRKAA1	T166	V160F	160	Missense	distal	-6	no	65.932	67.218	EPSD	TCGA	56.683	Up-regulation
CAMK_CAMKL_AMPK_PRKAA1_ST	P41235	HNF4A	Q13131	PRKAA1	T166	S170C	170	Missense	distal	4	no	65.932	46.185	EPSD	TCGA;COSMIC	56.683	Loss
CAMK_CAMKL_AMPK_PRKAA1_ST	P41235	HNF4A	Q13131	PRKAA1	S170	R177P	177	Missense	distal	7	no	56.727	56.815	EPSD	TCGA;ICGC;COSMIC	56.683	Up-regulation
CAMK_CAMKL_AMPK_PRKAA1_ST	P41235	HNF4A	Q13131	PRKAA1	S170	I176L	176	Missense	distal	6	no	56.727	57.183	EPSD	TCGA	56.683	Up-regulation
CAMK_CAMKL_AMPK_PRKAA1_ST	P41235	HNF4A	Q13131	PRKAA1	S170	S170C	170	Missense	central	0	yes	56.727	0.000	EPSD	TCGA;COSMIC	56.683	Loss
CAMK_CAMKL_AMPK_PRKAA1_ST	P41235	HNF4A	Q13131	PRKAA1	S170	G174S	174	Missense	distal	4	no	56.727	57.823	EPSD	TCGA;ICGC;COSMIC	56.683	Up-regulation
CAMK_CAMKL_AMPK_PRKAA1_ST	P41235	HNF4A	Q13131	PRKAA1	S170	D175N	175	Missense	distal	5	no	56.727	56.583	EPSD	TCGA;COSMIC	56.683	Loss
CAMK_CAMKL_AMPK_PRKAA1_ST	P41235	HNF4A	Q13131	PRKAA1	S303	D298N	298	Missense	distal	-5	no	58.110	44.034	EPSD	TCGA;COSMIC	56.683	Loss
CAMK_CAMKL_AMPK_PRKAA1_ST	P41235	HNF4A	Q13131	PRKAA1	S303	D304N	304	Missense	proximal	1	no	58.110	58.095	EPSD	TCGA;COSMIC;CCLE	56.683	Down-regulation
CAMK_CAMKL_AMPK_PRKAA1_ST	P41235	HNF4A	Q13131	PRKAA1	S313	S313F	313	Missense	central	0	yes	57.846	0.000	PhosphoSitePlus	TCGA;ICGC;COSMIC	56.683	Loss
CAMK_CAMKL_AMPK_PRKAA1_ST	P41235	HNF4A	Q13131	PRKAA1	T429	P433S	433	Missense	distal	4	no	56.583	56.735	EPSD	TCGA;COSMIC	56.683	Gain
CAMK_CAMKL_AMPK_PRKAA1_ST	P41235	HNF4A	Q13131	PRKAA1	T429	G425R	425	Missense	distal	-4	no	56.583	60.190	EPSD	TCGA;COSMIC	56.683	Gain
CAMK_CAMKL_AMPK_PRKAA1_ST	P41235	HNF4A	Q13131	PRKAA1	T429	R422Q	422	Missense	distal	-7	no	56.583	56.760	EPSD	TCGA;COSMIC	56.683	Gain
CAMK_CAMKL_AMPK_PRKAA1_ST	P49674	CSNK1E	Q13131	PRKAA1	S234	R227W	227	Missense	distal	-7	no	56.092	57.890	EPSD	TCGA;ICGC	56.683	Gain
CAMK_CAMKL_AMPK_PRKAA1_ST	P49674	CSNK1E	Q13131	PRKAA1	S234	I237S	237	Missense	distal	3	no	56.092	58.469	EPSD	TCGA;ICGC;COSMIC	56.683	Gain
CAMK_CAMKL_AMPK_PRKAA1_ST	P49674	CSNK1E	Q13131	PRKAA1	T250	Y251N	251	Missense	proximal	1	no	60.708	57.538	EPSD	TCGA;ICGC;COSMIC	56.683	Down-regulation
CAMK_CAMKL_AMPK_PRKAA1_ST	P49674	CSNK1E	Q13131	PRKAA1	T250	S257P	257	Missense	distal	7	no	60.708	60.211	EPSD	TCGA;ICGC;COSMIC	56.683	Down-regulation
CAMK_CAMKL_AMPK_PRKAA1_ST	P49674	CSNK1E	Q13131	PRKAA1	T250	E247K	247	Missense	distal	-3	no	60.708	64.549	EPSD	TCGA;ICGC;COSMIC	56.683	Up-regulation
CAMK_CAMKL_AMPK_PRKAA1_ST	P49674	CSNK1E	Q13131	PRKAA1	S368	S368L	368	Missense	central	0	yes	60.311	0.000	EPSD	TCGA;ICGC;COSMIC;GDSC;CCLE	56.683	Loss
CAMK_CAMKL_AMPK_PRKAA1_ST	P49674	CSNK1E	Q13131	PRKAA1	S368	A366V	366	Missense	proximal	-2	no	60.311	62.343	EPSD	TCGA;ICGC;COSMIC;CCLE	56.683	Up-regulation
CAMK_CAMKL_AMPK_PRKAA1_ST	P49674	CSNK1E	Q13131	PRKAA1	S368	S368P	368	Missense	central	0	yes	60.311	0.000	EPSD	TCGA;ICGC;COSMIC	56.683	Loss
CAMK_CAMKL_AMPK_PRKAA1_ST	P49674	CSNK1E	Q13131	PRKAA1	S368	E373D	373	Missense	distal	5	no	60.311	60.463	EPSD	TCGA	56.683	Up-regulation
CAMK_CAMKL_AMPK_PRKAA1_ST	P49674	CSNK1E	Q13131	PRKAA1	S377	E373D	373	Missense	distal	-4	no	60.788	60.749	EPSD	TCGA	56.683	Down-regulation
CAMK_CAMKL_AMPK_PRKAA1_ST	P49674	CSNK1E	Q13131	PRKAA1	S377	M378T	378	Missense	proximal	1	no	60.788	57.702	EPSD	TCGA;ICGC;COSMIC	56.683	Down-regulation
CAMK_CAMKL_AMPK_PRKAA1_ST	P49674	CSNK1E	Q13131	PRKAA1	S389	S389F	389	Missense	central	0	yes	66.528	0.000	PhosphoSitePlus	TCGA;ICGC;COSMIC	56.683	Loss
CAMK_CAMKL_AMPK_PRKAA1_ST	P49674	CSNK1E	Q13131	PRKAA1	S389	R396W	396	Missense	distal	7	no	66.528	66.753	PhosphoSitePlus	TCGA;ICGC	56.683	Up-regulation
CAMK_CAMKL_AMPK_PRKAA1_ST	P49674	CSNK1E	Q13131	PRKAA1	S389	N387S	387	Missense	proximal	-2	no	66.528	67.188	PhosphoSitePlus	TCGA;ICGC;COSMIC	56.683	Up-regulation
CAMK_CAMKL_AMPK_PRKAA1_ST	P49674	CSNK1E	Q13131	PRKAA1	S390	S389F	389	Missense	proximal	-1	no	63.455	63.409	EPSD	TCGA;ICGC;COSMIC	56.683	Down-regulation
CAMK_CAMKL_AMPK_PRKAA1_ST	P49674	CSNK1E	Q13131	PRKAA1	S390	R396W	396	Missense	distal	6	no	63.455	62.965	EPSD	TCGA;ICGC	56.683	Down-regulation
CAMK_CAMKL_AMPK_PRKAA1_ST	P49674	CSNK1E	Q13131	PRKAA1	S390	N387S	387	Missense	distal	-3	no	63.455	59.996	EPSD	TCGA;ICGC;COSMIC	56.683	Down-regulation
CAMK_CAMKL_AMPK_PRKAA1_ST	P49674	CSNK1E	Q13131	PRKAA1	S391	N387S	387	Missense	distal	-4	no	55.516	60.316	EPSD	TCGA;ICGC;COSMIC	56.683	Gain
CAMK_CAMKL_AMPK_PRKAA1_ST	P49674	CSNK1E	Q13131	PRKAA1	T407	R401Q	401	Missense	distal	-6	no	57.400	57.758	EPSD	TCGA;ICGC;COSMIC	56.683	Up-regulation
CAMK_CAMKL_AMPK_PRKAA1_ST	P49674	CSNK1E	Q13131	PRKAA1	T407	A404V	404	Missense	distal	-3	no	57.400	59.843	EPSD	TCGA;ICGC;COSMIC	56.683	Up-regulation
CAMK_CAMKL_AMPK_PRKAA1_ST	P49674	CSNK1E	Q13131	PRKAA1	T407	R401W	401	Missense	distal	-6	no	57.400	52.588	EPSD	TCGA;ICGC	56.683	Loss
CAMK_CAMKL_AMPK_PRKAA1_ST	P04626	ERBB2	Q13131	PRKAA1	S196	S196F	196	Missense	central	0	yes	64.227	0.000	EPSD	TCGA;COSMIC	56.683	Loss
CAMK_CAMKL_AMPK_PRKAA1_ST	P04626	ERBB2	Q13131	PRKAA1	S196	R203C	203	Missense	distal	7	no	64.227	64.260	EPSD	TCGA;COSMIC	56.683	Up-regulation
CAMK_CAMKL_AMPK_PRKAA1_ST	P04626	ERBB2	Q13131	PRKAA1	T686	R688Q	688	Missense	proximal	2	no	58.408	57.931	EPSD	TCGA;COSMIC	56.683	Down-regulation
CAMK_CAMKL_AMPK_PRKAA1_ST	P04626	ERBB2	Q13131	PRKAA1	T686	T686M	686	Missense	central	0	yes	58.408	0.000	EPSD	TCGA;COSMIC	56.683	Loss
CAMK_CAMKL_AMPK_PRKAA1_ST	P04626	ERBB2	Q13131	PRKAA1	S760	L755S	755	Missense	distal	-5	no	58.153	53.971	EPSD	TCGA;COSMIC;GDSC;CCLE	56.683	Loss
CAMK_CAMKL_AMPK_PRKAA1_ST	P04626	ERBB2	Q13131	PRKAA1	S760	I767M	767	Missense	distal	7	no	58.153	57.283	EPSD	TCGA;COSMIC	56.683	Down-regulation
CAMK_CAMKL_AMPK_PRKAA1_ST	P04626	ERBB2	Q13131	PRKAA1	S760	L755M	755	Missense	distal	-5	no	58.153	57.985	EPSD	TCGA;COSMIC	56.683	Down-regulation
CAMK_CAMKL_AMPK_PRKAA1_ST	P04626	ERBB2	Q13131	PRKAA1	S760	L755W	755	Missense	distal	-5	no	58.153	51.783	EPSD	TCGA;COSMIC	56.683	Loss
CAMK_CAMKL_AMPK_PRKAA1_ST	P04626	ERBB2	Q13131	PRKAA1	S760	R756K	756	Missense	distal	-4	no	58.153	54.973	EPSD	TCGA;COSMIC	56.683	Loss
CAMK_CAMKL_AMPK_PRKAA1_ST	P04626	ERBB2	Q13131	PRKAA1	S760	I767F	767	Missense	distal	7	no	58.153	57.977	EPSD	TCGA;COSMIC	56.683	Down-regulation
CAMK_CAMKL_AMPK_PRKAA1_ST	P04626	ERBB2	Q13131	PRKAA1	T900	R897Q	897	Missense	distal	-3	no	66.903	58.958	PhosphoSitePlus	TCGA;COSMIC	56.683	Down-regulation
CAMK_CAMKL_AMPK_PRKAA1_ST	P04626	ERBB2	Q13131	PRKAA1	S1051	G1057V	1057	Missense	distal	6	no	60.932	61.049	EPSD	TCGA;COSMIC	56.683	Up-regulation
CAMK_CAMKL_AMPK_PRKAA1_ST	Q14694	USP10	Q13131	PRKAA1	S35	E30D	30	Missense	distal	-5	no	68.183	64.767	EPSD	TCGA;COSMIC	56.683	Down-regulation
CAMK_CAMKL_AMPK_PRKAA1_ST	Q14694	USP10	Q13131	PRKAA1	S76	L71F	71	Missense	distal	-5	no	64.269	58.745	PhosphoSitePlus	TCGA;ICGC;COSMIC	56.683	Down-regulation
CAMK_CAMKL_AMPK_PRKAA1_ST	Q14694	USP10	Q13131	PRKAA1	S76	L83P	83	Missense	distal	7	no	64.269	63.729	PhosphoSitePlus	TCGA;COSMIC	56.683	Down-regulation
CAMK_CAMKL_AMPK_PRKAA1_ST	Q14694	USP10	Q13131	PRKAA1	S109	I113F	113	Missense	distal	4	no	58.285	57.167	EPSD	TCGA;COSMIC	56.683	Down-regulation
CAMK_CAMKL_AMPK_PRKAA1_ST	Q14694	USP10	Q13131	PRKAA1	S218	S215F	215	Missense	distal	-3	no	57.112	57.260	EPSD	TCGA;COSMIC	56.683	Up-regulation
CAMK_CAMKL_AMPK_PRKAA1_ST	Q14694	USP10	Q13131	PRKAA1	S331	D325G	325	Missense	distal	-6	no	57.713	54.834	EPSD	TCGA;ICGC;COSMIC	56.683	Loss
CAMK_CAMKL_AMPK_PRKAA1_ST	Q14694	USP10	Q13131	PRKAA1	T674	R671Q	671	Missense	distal	-3	no	66.781	58.836	EPSD	TCGA;COSMIC	56.683	Down-regulation
CAMK_CAMKL_AMPK_PRKAA1_ST	Q14694	USP10	Q13131	PRKAA1	T674	L675V	675	Missense	proximal	1	no	66.781	67.571	EPSD	TCGA;COSMIC	56.683	Up-regulation
CAMK_CAMKL_AMPK_PRKAA1_ST	Q14694	USP10	Q13131	PRKAA1	T674	P679S	679	Missense	distal	5	no	66.781	66.742	EPSD	TCGA;COSMIC	56.683	Down-regulation
CAMK_CAMKL_AMPK_PRKAA1_ST	Q14694	USP10	Q13131	PRKAA1	T674	P680H	680	Missense	distal	6	no	66.781	66.795	EPSD	TCGA;COSMIC	56.683	Up-regulation
CAMK_CAMKL_AMPK_PRKAA1_ST	Q14694	USP10	Q13131	PRKAA1	S713	V708M	708	Missense	distal	-5	no	56.236	60.932	EPSD	TCGA;COSMIC	56.683	Gain
CAMK_CAMKL_AMPK_PRKAA1_ST	P22460	KCNA5	Q13131	PRKAA1	S559	K565N	565	Missense	distal	6	no	57.162	57.100	PhosphoSitePlus	TCGA;ICGC;COSMIC	56.683	Down-regulation
CAMK_CAMKL_AMPK_PRKAA1_ST	P22460	KCNA5	Q13131	PRKAA1	S559	A566V	566	Missense	distal	7	no	57.162	54.744	PhosphoSitePlus	TCGA;ICGC	56.683	Loss
CAMK_CAMKL_AMPK_PRKAA1_ST	P22460	KCNA5	Q13131	PRKAA1	S559	S562F	562	Missense	distal	3	no	57.162	55.954	PhosphoSitePlus	TCGA;ICGC;COSMIC	56.683	Loss
CAMK_CAMKL_AMPK_PRKAA1_ST	P22460	KCNA5	Q13131	PRKAA1	S559	G558R	558	Missense	proximal	-1	no	57.162	57.124	PhosphoSitePlus	TCGA;ICGC	56.683	Down-regulation
CAMK_CAMKL_AMPK_PRKAA1_ST	P22460	KCNA5	Q13131	PRKAA1	S559	G561E	561	Missense	proximal	2	no	57.162	58.275	PhosphoSitePlus	TCGA;ICGC;COSMIC	56.683	Up-regulation
CAMK_CAMKL_AMPK_PRKAA1_ST	P22460	KCNA5	Q13131	PRKAA1	S559	R554Q	554	Missense	distal	-5	no	57.162	51.480	PhosphoSitePlus	TCGA;ICGC;COSMIC	56.683	Loss
CAMK_CAMKL_AMPK_PRKAA1_ST	Q9BUB5	MKNK1	Q13131	PRKAA1	S237	G236S	236	Missense	proximal	-1	no	58.332	58.326	EPSD	TCGA;COSMIC	56.683	Down-regulation
CAMK_CAMKL_AMPK_PRKAA1_ST	Q9BUB5	MKNK1	Q13131	PRKAA1	S394	F401L	401	Missense	distal	7	no	61.920	63.230	EPSD	TCGA;COSMIC	56.683	Up-regulation
CAMK_CAMKL_AMPK_PRKAA1_ST	Q9BUB5	MKNK1	Q13131	PRKAA1	T395	F401L	401	Missense	distal	6	no	57.696	57.564	EPSD	TCGA;COSMIC	56.683	Down-regulation
CAMK_CAMKL_AMPK_PRKAA1_ST	Q9BUB5	MKNK1	Q13131	PRKAA1	T395	A402P	402	Missense	distal	7	no	57.696	57.070	EPSD	TCGA;COSMIC	56.683	Down-regulation
CAMK_CAMKL_AMPK_PRKAA1_ST	Q9BUB5	MKNK1	Q13131	PRKAA1	T395	A402T	402	Missense	distal	7	no	57.696	57.322	EPSD	TCGA;COSMIC	56.683	Down-regulation
CAMK_CAMKL_AMPK_PRKAA1_ST	Q9BUB5	MKNK1	Q13131	PRKAA1	S433	S437F	437	Missense	distal	4	no	55.591	57.983	EPSD	TCGA;COSMIC	56.683	Gain
CAMK_CAMKL_AMPK_PRKAA1_ST	Q9BUB5	MKNK1	Q13131	PRKAA1	S437	P439S	439	Missense	proximal	2	no	60.055	59.512	EPSD	TCGA;COSMIC	56.683	Down-regulation
CAMK_CAMKL_AMPK_PRKAA1_ST	Q9BUB5	MKNK1	Q13131	PRKAA1	S437	R443C	443	Missense	distal	6	no	60.055	60.386	EPSD	TCGA;COSMIC	56.683	Up-regulation
CAMK_CAMKL_AMPK_PRKAA1_ST	Q9BUB5	MKNK1	Q13131	PRKAA1	S437	S437F	437	Missense	central	0	yes	60.055	0.000	EPSD	TCGA;COSMIC	56.683	Loss
CAMK_CAMKL_AMPK_PRKAA1_ST	O15360	FANCA	Q13131	PRKAA1	S347	A349V	349	Missense	proximal	2	no	62.410	63.556	PhosphoSitePlus	TCGA;ICGC;COSMIC	56.683	Up-regulation
CAMK_CAMKL_AMPK_PRKAA1_ST	O15360	FANCA	Q13131	PRKAA1	T351	A349V	349	Missense	proximal	-2	no	54.675	56.708	EPSD	TCGA;ICGC;COSMIC	56.683	Gain
CAMK_CAMKL_AMPK_PRKAA1_ST	O15360	FANCA	Q13131	PRKAA1	S391	S394C	394	Missense	distal	3	no	60.490	58.659	EPSD	TCGA;ICGC;COSMIC	56.683	Down-regulation
CAMK_CAMKL_AMPK_PRKAA1_ST	O15360	FANCA	Q13131	PRKAA1	S535	E532K	532	Missense	distal	-3	no	53.722	57.563	EPSD	TCGA;ICGC	56.683	Gain
CAMK_CAMKL_AMPK_PRKAA1_ST	O15360	FANCA	Q13131	PRKAA1	S1149	D1147V	1147	Missense	proximal	-2	no	55.456	57.176	EPSD	TCGA;ICGC;COSMIC	56.683	Gain
CAMK_CAMKL_AMPK_PRKAA1_ST	O95239	KIF4A	Q13131	PRKAA1	T199	A204D	204	Missense	distal	5	no	56.641	56.702	EPSD	TCGA;ICGC;COSMIC	56.683	Gain
CAMK_CAMKL_AMPK_PRKAA1_ST	O95239	KIF4A	Q13131	PRKAA1	T199	A201V	201	Missense	proximal	2	no	56.641	57.787	EPSD	TCGA;ICGC;COSMIC	56.683	Gain
CAMK_CAMKL_AMPK_PRKAA1_ST	O95239	KIF4A	Q13131	PRKAA1	T199	T203A	203	Missense	distal	4	no	56.641	59.209	EPSD	TCGA;ICGC;COSMIC	56.683	Gain
CAMK_CAMKL_AMPK_PRKAA1_ST	O95239	KIF4A	Q13131	PRKAA1	T500	T504M	504	Missense	distal	4	no	57.122	61.645	EPSD	TCGA;ICGC	56.683	Up-regulation
CAMK_CAMKL_AMPK_PRKAA1_ST	O95239	KIF4A	Q13131	PRKAA1	T544	A538V	538	Missense	distal	-6	no	65.878	64.027	EPSD	TCGA;ICGC;COSMIC	56.683	Down-regulation
CAMK_CAMKL_AMPK_PRKAA1_ST	O95239	KIF4A	Q13131	PRKAA1	S634	R631H	631	Missense	distal	-3	no	58.391	50.534	EPSD	TCGA;ICGC;COSMIC	56.683	Loss
CAMK_CAMKL_AMPK_PRKAA1_ST	O95239	KIF4A	Q13131	PRKAA1	S634	T632N	632	Missense	proximal	-2	no	58.391	60.414	EPSD	TCGA;ICGC;COSMIC	56.683	Up-regulation
CAMK_CAMKL_AMPK_PRKAA1_ST	O95239	KIF4A	Q13131	PRKAA1	S634	T629I	629	Missense	distal	-5	no	58.391	64.633	EPSD	TCGA;ICGC;COSMIC	56.683	Up-regulation
CAMK_CAMKL_AMPK_PRKAA1_ST	O95239	KIF4A	Q13131	PRKAA1	S787	Q780E	780	Missense	distal	-7	no	57.804	57.837	EPSD	TCGA;ICGC;COSMIC	56.683	Up-regulation
CAMK_CAMKL_AMPK_PRKAA1_ST	O95239	KIF4A	Q13131	PRKAA1	S787	E789D	789	Missense	proximal	2	no	57.804	57.844	EPSD	TCGA;ICGC	56.683	Up-regulation
CAMK_CAMKL_AMPK_PRKAA1_ST	O95239	KIF4A	Q13131	PRKAA1	T799	R806C	806	Missense	distal	7	no	56.949	56.982	EPSD	TCGA;ICGC;COSMIC;CCLE	56.683	Up-regulation
CAMK_CAMKL_AMPK_PRKAA1_ST	O95239	KIF4A	Q13131	PRKAA1	S801	R806C	806	Missense	distal	5	no	69.354	69.355	PhosphoSitePlus	TCGA;ICGC;COSMIC;CCLE	56.683	Up-regulation
CAMK_CAMKL_AMPK_PRKAA1_ST	O95239	KIF4A	Q13131	PRKAA1	S815	S810L	810	Missense	distal	-5	no	53.471	57.653	EPSD	TCGA;ICGC;COSMIC	56.683	Gain
CAMK_CAMKL_AMPK_PRKAA1_ST	O95239	KIF4A	Q13131	PRKAA1	S894	A896D	896	Missense	proximal	2	no	60.543	61.386	EPSD	TCGA;ICGC;COSMIC	56.683	Up-regulation
CAMK_CAMKL_AMPK_PRKAA1_ST	O95239	KIF4A	Q13131	PRKAA1	S894	M898V	898	Missense	distal	4	no	60.543	58.622	EPSD	TCGA;ICGC;COSMIC	56.683	Down-regulation
CAMK_CAMKL_AMPK_PRKAA1_ST	O95239	KIF4A	Q13131	PRKAA1	S1017	D1015N	1015	Missense	proximal	-2	no	61.038	62.090	EPSD	TCGA;ICGC;COSMIC	56.683	Up-regulation
CAMK_CAMKL_AMPK_PRKAA1_ST	O95239	KIF4A	Q13131	PRKAA1	S1017	S1017Y	1017	Missense	central	0	yes	61.038	0.000	EPSD	TCGA;ICGC;COSMIC	56.683	Loss
CAMK_CAMKL_AMPK_PRKAA1_ST	O95239	KIF4A	Q13131	PRKAA1	S1048	E1049A	1049	Missense	proximal	1	no	58.577	58.033	EPSD	TCGA;ICGC;COSMIC	56.683	Down-regulation
CAMK_CAMKL_AMPK_PRKAA1_ST	O95239	KIF4A	Q13131	PRKAA1	T1115	C1112R	1112	Missense	distal	-3	no	51.887	66.035	EPSD	TCGA;ICGC;COSMIC	56.683	Gain
CAMK_CAMKL_AMPK_PRKAA1_ST	O95239	KIF4A	Q13131	PRKAA1	S1178	C1171G	1171	Missense	distal	-7	no	56.142	58.950	EPSD	TCGA;ICGC	56.683	Gain
CAMK_CAMKL_AMPK_PRKAA1_ST	O95239	KIF4A	Q13131	PRKAA1	S1186	K1179N	1179	Missense	distal	-7	no	58.170	56.472	EPSD	TCGA;ICGC;COSMIC	56.683	Loss
CAMK_CAMKL_AMPK_PRKAA1_ST	O95239	KIF4A	Q13131	PRKAA1	S1186	P1185S	1185	Missense	proximal	-1	no	58.170	58.215	EPSD	TCGA;ICGC;COSMIC	56.683	Up-regulation
CAMK_CAMKL_AMPK_PRKAA1_ST	O95239	KIF4A	Q13131	PRKAA1	S1186	P1185L	1185	Missense	proximal	-1	no	58.170	58.241	EPSD	TCGA;ICGC;COSMIC	56.683	Up-regulation
CAMK_CAMKL_AMPK_PRKAA1_ST	O95239	KIF4A	Q13131	PRKAA1	S1216	N1217H	1217	Missense	proximal	1	no	53.974	56.839	EPSD	TCGA;ICGC;COSMIC	56.683	Gain
CAMK_CAMKL_AMPK_PRKAA1_ST	O75385	ULK1	Q13131	PRKAA1	S111	D113E	113	Missense	proximal	2	no	57.033	56.993	EPSD	TCGA;ICGC;COSMIC	56.683	Down-regulation
CAMK_CAMKL_AMPK_PRKAA1_ST	O75385	ULK1	Q13131	PRKAA1	S294	P291R	291	Missense	distal	-3	no	53.395	62.255	EPSD	TCGA;ICGC;COSMIC	56.683	Gain
CAMK_CAMKL_AMPK_PRKAA1_ST	O75385	ULK1	Q13131	PRKAA1	S304	S310F	310	Missense	distal	6	no	62.291	62.556	EPSD	TCGA;ICGC;COSMIC	56.683	Up-regulation
CAMK_CAMKL_AMPK_PRKAA1_ST	O75385	ULK1	Q13131	PRKAA1	S304	S305N	305	Missense	proximal	1	no	62.291	61.437	EPSD	TCGA;ICGC;COSMIC	56.683	Down-regulation
CAMK_CAMKL_AMPK_PRKAA1_ST	O75385	ULK1	Q13131	PRKAA1	S317	S310F	310	Missense	distal	-7	no	64.086	61.493	EPSD	TCGA;ICGC;COSMIC	56.683	Down-regulation
CAMK_CAMKL_AMPK_PRKAA1_ST	O75385	ULK1	Q13131	PRKAA1	S317	S317F	317	Missense	central	0	yes	64.086	0.000	EPSD	TCGA;ICGC;COSMIC;GDSC	56.683	Loss
CAMK_CAMKL_AMPK_PRKAA1_ST	O75385	ULK1	Q13131	PRKAA1	S317	L312P	312	Missense	distal	-5	no	64.086	59.346	EPSD	TCGA;ICGC;COSMIC	56.683	Down-regulation
CAMK_CAMKL_AMPK_PRKAA1_ST	O75385	ULK1	Q13131	PRKAA1	S317	E320K	320	Missense	distal	3	no	64.086	65.811	EPSD	TCGA;ICGC;COSMIC;GDSC	56.683	Up-regulation
CAMK_CAMKL_AMPK_PRKAA1_ST	O75385	ULK1	Q13131	PRKAA1	S424	P431L	431	Missense	distal	7	no	57.223	57.763	EPSD	TCGA;ICGC;COSMIC	56.683	Up-regulation
CAMK_CAMKL_AMPK_PRKAA1_ST	O75385	ULK1	Q13131	PRKAA1	S424	R417W	417	Missense	distal	-7	no	57.223	59.022	EPSD	TCGA;ICGC;COSMIC	56.683	Up-regulation
CAMK_CAMKL_AMPK_PRKAA1_ST	O75385	ULK1	Q13131	PRKAA1	S467	S460C	460	Missense	distal	-7	no	72.895	70.506	EPSD	TCGA;ICGC;COSMIC	56.683	Down-regulation
CAMK_CAMKL_AMPK_PRKAA1_ST	O75385	ULK1	Q13131	PRKAA1	S467	G466C	466	Missense	proximal	-1	no	72.895	73.003	EPSD	TCGA;ICGC;COSMIC	56.683	Up-regulation
CAMK_CAMKL_AMPK_PRKAA1_ST	O75385	ULK1	Q13131	PRKAA1	S469	G466C	466	Missense	distal	-3	no	62.045	56.933	EPSD	TCGA;ICGC;COSMIC	56.683	Down-regulation
CAMK_CAMKL_AMPK_PRKAA1_ST	O75385	ULK1	Q13131	PRKAA1	S495	V489F	489	Missense	distal	-6	no	66.399	67.685	EPSD	TCGA;ICGC;COSMIC	56.683	Up-regulation
CAMK_CAMKL_AMPK_PRKAA1_ST	O75385	ULK1	Q13131	PRKAA1	S495	R500W	500	Missense	distal	5	no	66.399	66.270	EPSD	TCGA;ICGC;COSMIC	56.683	Down-regulation
CAMK_CAMKL_AMPK_PRKAA1_ST	O75385	ULK1	Q13131	PRKAA1	S538	S544C	544	Missense	distal	6	no	59.648	59.872	EPSD	TCGA;ICGC;COSMIC	56.683	Up-regulation
CAMK_CAMKL_AMPK_PRKAA1_ST	O75385	ULK1	Q13131	PRKAA1	S538	P536A	536	Missense	proximal	-2	no	59.648	57.075	EPSD	TCGA;ICGC;COSMIC	56.683	Down-regulation
CAMK_CAMKL_AMPK_PRKAA1_ST	O75385	ULK1	Q13131	PRKAA1	S538	P534S	534	Missense	distal	-4	no	59.648	60.891	EPSD	TCGA;ICGC;COSMIC	56.683	Up-regulation
CAMK_CAMKL_AMPK_PRKAA1_ST	O75385	ULK1	Q13131	PRKAA1	S538	P534L	534	Missense	distal	-4	no	59.648	59.397	EPSD	TCGA;ICGC;COSMIC	56.683	Down-regulation
CAMK_CAMKL_AMPK_PRKAA1_ST	O75385	ULK1	Q13131	PRKAA1	S538	R535H	535	Missense	distal	-3	no	59.648	51.792	EPSD	TCGA;ICGC	56.683	Loss
CAMK_CAMKL_AMPK_PRKAA1_ST	O75385	ULK1	Q13131	PRKAA1	S556	G549R	549	Missense	distal	-7	no	75.749	74.334	EPSD	TCGA;ICGC;COSMIC	56.683	Down-regulation
CAMK_CAMKL_AMPK_PRKAA1_ST	O75385	ULK1	Q13131	PRKAA1	S556	C552Y	552	Missense	distal	-4	no	75.749	67.513	EPSD	TCGA;ICGC;COSMIC	56.683	Down-regulation
CAMK_CAMKL_AMPK_PRKAA1_ST	O75385	ULK1	Q13131	PRKAA1	S556	S556I	556	Missense	central	0	yes	75.749	0.000	EPSD	TCGA;ICGC;COSMIC	56.683	Loss
CAMK_CAMKL_AMPK_PRKAA1_ST	O75385	ULK1	Q13131	PRKAA1	S598	G595R	595	Missense	distal	-3	no	49.464	58.499	EPSD	TCGA;ICGC;COSMIC	56.683	Gain
CAMK_CAMKL_AMPK_PRKAA1_ST	O75385	ULK1	Q13131	PRKAA1	T625	P629L	629	Missense	distal	4	no	50.174	56.914	EPSD	TCGA;ICGC;COSMIC	56.683	Gain
CAMK_CAMKL_AMPK_PRKAA1_ST	O75385	ULK1	Q13131	PRKAA1	S638	P637T	637	Missense	proximal	-1	no	63.868	63.856	PhosphoSitePlus	TCGA;ICGC;COSMIC	56.683	Down-regulation
CAMK_CAMKL_AMPK_PRKAA1_ST	O75385	ULK1	Q13131	PRKAA1	S638	T636A	636	Missense	proximal	-2	no	63.868	64.526	PhosphoSitePlus	TCGA;ICGC;COSMIC	56.683	Up-regulation
CAMK_CAMKL_AMPK_PRKAA1_ST	O75385	ULK1	Q13131	PRKAA1	S638	A644V	644	Missense	distal	6	no	63.868	63.663	PhosphoSitePlus	TCGA;ICGC;COSMIC	56.683	Down-regulation
CAMK_CAMKL_AMPK_PRKAA1_ST	O75385	ULK1	Q13131	PRKAA1	S638	P637S	637	Missense	proximal	-1	no	63.868	63.913	PhosphoSitePlus	TCGA;ICGC;COSMIC	56.683	Up-regulation
CAMK_CAMKL_AMPK_PRKAA1_ST	O75385	ULK1	Q13131	PRKAA1	T660	R657Q	657	Missense	distal	-3	no	65.978	58.034	EPSD	TCGA;ICGC;COSMIC	56.683	Down-regulation
CAMK_CAMKL_AMPK_PRKAA1_ST	O75385	ULK1	Q13131	PRKAA1	S694	R697L	697	Missense	distal	3	no	59.634	58.303	EPSD	TCGA;ICGC;COSMIC	56.683	Down-regulation
CAMK_CAMKL_AMPK_PRKAA1_ST	O75385	ULK1	Q13131	PRKAA1	S694	P688L	688	Missense	distal	-6	no	59.634	59.595	EPSD	TCGA;ICGC;COSMIC	56.683	Down-regulation
CAMK_CAMKL_AMPK_PRKAA1_ST	O75385	ULK1	Q13131	PRKAA1	S775	R770C	770	Missense	distal	-5	no	57.899	56.545	EPSD	TCGA;ICGC;COSMIC	56.683	Loss
CAMK_CAMKL_AMPK_PRKAA1_ST	O75385	ULK1	Q13131	PRKAA1	S775	S775P	775	Missense	central	0	yes	57.899	0.000	EPSD	TCGA;ICGC	56.683	Loss
CAMK_CAMKL_AMPK_PRKAA1_ST	O15350	TP73	Q13131	PRKAA1	T27	S34L	34	Missense	distal	7	no	69.200	69.241	EPSD	TCGA;ICGC;COSMIC	56.683	Up-regulation
CAMK_CAMKL_AMPK_PRKAA1_ST	O15350	TP73	Q13131	PRKAA1	S223	S223L	223	Missense	central	0	yes	58.421	0.000	EPSD	TCGA;ICGC;COSMIC	56.683	Loss
CAMK_CAMKL_AMPK_PRKAA1_ST	O15350	TP73	Q13131	PRKAA1	S223	V230D	230	Missense	distal	7	no	58.421	59.491	EPSD	TCGA;ICGC;COSMIC	56.683	Up-regulation
CAMK_CAMKL_AMPK_PRKAA1_ST	O15350	TP73	Q13131	PRKAA1	S223	E218K	218	Missense	distal	-5	no	58.421	55.773	EPSD	TCGA;ICGC;COSMIC	56.683	Loss
CAMK_CAMKL_AMPK_PRKAA1_ST	O15350	TP73	Q13131	PRKAA1	S426	G419W	419	Missense	distal	-7	no	65.075	65.458	PhosphoSitePlus	TCGA;COSMIC	56.683	Up-regulation
CAMK_CAMKL_AMPK_PRKAA1_ST	O15350	TP73	Q13131	PRKAA1	S471	A472T	472	Missense	proximal	1	no	61.982	62.535	EPSD	TCGA;COSMIC;GDSC;CCLE	56.683	Up-regulation
CAMK_CAMKL_AMPK_PRKAA1_ST	Q05469	LIPE	Q13131	PRKAA1	S200	F206L	206	Missense	distal	6	no	63.427	63.294	EPSD	TCGA;ICGC;COSMIC	56.683	Down-regulation
CAMK_CAMKL_AMPK_PRKAA1_ST	Q05469	LIPE	Q13131	PRKAA1	S200	S200Y	200	Missense	central	0	yes	63.427	0.000	EPSD	TCGA;ICGC	56.683	Loss
CAMK_CAMKL_AMPK_PRKAA1_ST	Q05469	LIPE	Q13131	PRKAA1	T202	F206L	206	Missense	distal	4	no	56.926	61.121	EPSD	TCGA;ICGC;COSMIC	56.683	Up-regulation
CAMK_CAMKL_AMPK_PRKAA1_ST	Q05469	LIPE	Q13131	PRKAA1	T202	S200Y	200	Missense	proximal	-2	no	56.926	55.364	EPSD	TCGA;ICGC	56.683	Loss
CAMK_CAMKL_AMPK_PRKAA1_ST	Q05469	LIPE	Q13131	PRKAA1	S607	L610P	610	Missense	distal	3	no	63.227	62.972	EPSD	TCGA;ICGC;COSMIC	56.683	Down-regulation
CAMK_CAMKL_AMPK_PRKAA1_ST	Q05469	LIPE	Q13131	PRKAA1	S621	G627S	627	Missense	distal	6	no	56.754	56.982	EPSD	TCGA;ICGC;COSMIC	56.683	Up-regulation
CAMK_CAMKL_AMPK_PRKAA1_ST	Q05469	LIPE	Q13131	PRKAA1	T813	R810Q	810	Missense	distal	-3	no	63.032	55.087	EPSD	TCGA;ICGC;COSMIC;GDSC	56.683	Loss
CAMK_CAMKL_AMPK_PRKAA1_ST	Q05469	LIPE	Q13131	PRKAA1	S855	E856K	856	Missense	proximal	1	no	68.178	69.108	PhosphoSitePlus	TCGA;ICGC;COSMIC	56.683	Up-regulation
CAMK_CAMKL_AMPK_PRKAA1_ST	Q05469	LIPE	Q13131	PRKAA1	S855	P849L	849	Missense	distal	-6	no	68.178	68.139	PhosphoSitePlus	TCGA;ICGC;COSMIC	56.683	Down-regulation
CAMK_CAMKL_AMPK_PRKAA1_ST	Q05469	LIPE	Q13131	PRKAA1	S855	R851C	851	Missense	distal	-4	no	68.178	72.489	PhosphoSitePlus	TCGA;ICGC;COSMIC	56.683	Up-regulation
CAMK_CAMKL_AMPK_PRKAA1_ST	Q05469	LIPE	Q13131	PRKAA1	S855	R851H	851	Missense	distal	-4	no	68.178	64.792	PhosphoSitePlus	TCGA;ICGC;COSMIC	56.683	Down-regulation
CAMK_CAMKL_AMPK_PRKAA1_ST	Q05469	LIPE	Q13131	PRKAA1	T875	L879F	879	Missense	distal	4	no	65.124	60.929	EPSD	TCGA;ICGC;COSMIC	56.683	Down-regulation
CAMK_CAMKL_AMPK_PRKAA1_ST	Q05469	LIPE	Q13131	PRKAA1	T875	L874M	874	Missense	proximal	-1	no	65.124	65.116	EPSD	TCGA;ICGC;COSMIC	56.683	Down-regulation
CAMK_CAMKL_AMPK_PRKAA1_ST	Q05469	LIPE	Q13131	PRKAA1	T875	K872N	872	Missense	distal	-3	no	65.124	63.829	EPSD	TCGA;ICGC;COSMIC;CCLE	56.683	Down-regulation
CAMK_CAMKL_AMPK_PRKAA1_ST	Q05469	LIPE	Q13131	PRKAA1	S904	E899Q	899	Missense	distal	-5	no	57.314	52.073	EPSD	TCGA;ICGC;COSMIC	56.683	Loss
CAMK_CAMKL_AMPK_PRKAA1_ST	Q05469	LIPE	Q13131	PRKAA1	S962	P963S	963	Missense	proximal	1	no	56.579	57.212	EPSD	TCGA;ICGC	56.683	Gain
CAMK_CAMKL_AMPK_PRKAA1_ST	Q6N021	TET2	Q13131	PRKAA1	T32	T27I	27	Missense	distal	-5	no	54.634	60.876	EPSD	TCGA;ICGC;COSMIC	56.683	Gain
CAMK_CAMKL_AMPK_PRKAA1_ST	Q6N021	TET2	Q13131	PRKAA1	S99	L103R	103	Missense	distal	4	no	59.609	54.128	PhosphoSitePlus	TCGA;ICGC;COSMIC	56.683	Loss
CAMK_CAMKL_AMPK_PRKAA1_ST	Q6N021	TET2	Q13131	PRKAA1	S99	G92E	92	Missense	distal	-7	no	59.609	58.404	PhosphoSitePlus	TCGA;ICGC;COSMIC	56.683	Down-regulation
CAMK_CAMKL_AMPK_PRKAA1_ST	Q6N021	TET2	Q13131	PRKAA1	S99	G92R	92	Missense	distal	-7	no	59.609	58.194	PhosphoSitePlus	TCGA;ICGC;COSMIC	56.683	Down-regulation
CAMK_CAMKL_AMPK_PRKAA1_ST	Q6N021	TET2	Q13131	PRKAA1	S99	G105R	105	Missense	distal	6	no	59.609	59.731	PhosphoSitePlus	TCGA;ICGC;COSMIC	56.683	Up-regulation
CAMK_CAMKL_AMPK_PRKAA1_ST	Q6N021	TET2	Q13131	PRKAA1	S315	S315F	315	Missense	central	0	yes	58.201	0.000	EPSD	TCGA;ICGC;COSMIC	56.683	Loss
CAMK_CAMKL_AMPK_PRKAA1_ST	Q6N021	TET2	Q13131	PRKAA1	S315	F316I	316	Missense	proximal	1	no	58.201	52.082	EPSD	TCGA;ICGC;COSMIC	56.683	Loss
CAMK_CAMKL_AMPK_PRKAA1_ST	Q6N021	TET2	Q13131	PRKAA1	S315	E320K	320	Missense	distal	5	no	58.201	58.222	EPSD	TCGA;ICGC;COSMIC	56.683	Up-regulation
CAMK_CAMKL_AMPK_PRKAA1_ST	Q6N021	TET2	Q13131	PRKAA1	S327	E330K	330	Missense	distal	3	no	57.664	59.388	EPSD	TCGA;ICGC;COSMIC	56.683	Up-regulation
CAMK_CAMKL_AMPK_PRKAA1_ST	Q6N021	TET2	Q13131	PRKAA1	S327	E330Q	330	Missense	distal	3	no	57.664	59.376	EPSD	TCGA;ICGC;COSMIC	56.683	Up-regulation
CAMK_CAMKL_AMPK_PRKAA1_ST	Q6N021	TET2	Q13131	PRKAA1	S327	S327L	327	Missense	central	0	yes	57.664	0.000	EPSD	TCGA;ICGC;COSMIC	56.683	Loss
CAMK_CAMKL_AMPK_PRKAA1_ST	Q6N021	TET2	Q13131	PRKAA1	S327	E320K	320	Missense	distal	-7	no	57.664	59.057	EPSD	TCGA;ICGC;COSMIC	56.683	Up-regulation
CAMK_CAMKL_AMPK_PRKAA1_ST	Q6N021	TET2	Q13131	PRKAA1	S327	Q324H	324	Missense	distal	-3	no	57.664	57.752	EPSD	TCGA;ICGC;COSMIC	56.683	Up-regulation
CAMK_CAMKL_AMPK_PRKAA1_ST	Q6N021	TET2	Q13131	PRKAA1	S471	P474S	474	Missense	distal	3	no	54.692	56.930	EPSD	TCGA;ICGC;COSMIC	56.683	Gain
CAMK_CAMKL_AMPK_PRKAA1_ST	Q6N021	TET2	Q13131	PRKAA1	S585	L579V	579	Missense	distal	-6	no	62.930	61.437	EPSD	TCGA;ICGC;COSMIC	56.683	Down-regulation
CAMK_CAMKL_AMPK_PRKAA1_ST	Q6N021	TET2	Q13131	PRKAA1	S585	Y592S	592	Missense	distal	7	no	62.930	62.682	EPSD	TCGA;ICGC;COSMIC	56.683	Down-regulation
CAMK_CAMKL_AMPK_PRKAA1_ST	Q6N021	TET2	Q13131	PRKAA1	S585	L590I	590	Missense	distal	5	no	62.930	62.861	EPSD	TCGA;ICGC	56.683	Down-regulation
CAMK_CAMKL_AMPK_PRKAA1_ST	Q6N021	TET2	Q13131	PRKAA1	S817	P818A	818	Missense	proximal	1	no	60.010	59.048	EPSD	TCGA;ICGC;COSMIC	56.683	Down-regulation
CAMK_CAMKL_AMPK_PRKAA1_ST	Q6N021	TET2	Q13131	PRKAA1	S817	R814H	814	Missense	distal	-3	no	60.010	52.154	EPSD	TCGA;ICGC;COSMIC;GDSC	56.683	Loss
CAMK_CAMKL_AMPK_PRKAA1_ST	Q6N021	TET2	Q13131	PRKAA1	S1076	T1069A	1069	Missense	distal	-7	no	60.091	59.242	EPSD	TCGA;ICGC;COSMIC	56.683	Down-regulation
CAMK_CAMKL_AMPK_PRKAA1_ST	Q6N021	TET2	Q13131	PRKAA1	S1449	R1451W	1451	Missense	proximal	2	no	64.294	64.379	EPSD	TCGA;ICGC;COSMIC	56.683	Up-regulation
CAMK_CAMKL_AMPK_PRKAA1_ST	Q6N021	TET2	Q13131	PRKAA1	S1449	R1451Q	1451	Missense	proximal	2	no	64.294	63.817	EPSD	TCGA;ICGC;COSMIC	56.683	Down-regulation
CAMK_CAMKL_AMPK_PRKAA1_ST	Q6N021	TET2	Q13131	PRKAA1	S1561	V1557D	1557	Missense	distal	-4	no	54.465	56.829	EPSD	TCGA	56.683	Gain
CAMK_CAMKL_AMPK_PRKAA1_ST	Q6N021	TET2	Q13131	PRKAA1	S1970	R1974M	1974	Missense	distal	4	no	60.402	63.308	EPSD	TCGA;ICGC;COSMIC	56.683	Up-regulation
CAMK_CAMKL_AMPK_PRKAA1_ST	Q6N021	TET2	Q13131	PRKAA1	S1970	S1970Y	1970	Missense	central	0	yes	60.402	0.000	EPSD	TCGA;ICGC;COSMIC	56.683	Loss
CAMK_CAMKL_AMPK_PRKAA1_ST	Q15910	EZH2	Q13131	PRKAA1	S212	R216Q	216	Missense	distal	4	no	59.827	55.743	EPSD	TCGA;COSMIC	56.683	Loss
CAMK_CAMKL_AMPK_PRKAA1_ST	Q15910	EZH2	Q13131	PRKAA1	S212	D208Y	208	Missense	distal	-4	no	59.827	55.995	EPSD	TCGA	56.683	Loss
CAMK_CAMKL_AMPK_PRKAA1_ST	Q15910	EZH2	Q13131	PRKAA1	S212	R207Q	207	Missense	distal	-5	no	59.827	54.145	EPSD	TCGA;ICGC;COSMIC	56.683	Loss
CAMK_CAMKL_AMPK_PRKAA1_ST	Q15910	EZH2	Q13131	PRKAA1	S277	S271Y	271	Missense	distal	-6	no	61.801	59.304	EPSD	TCGA;COSMIC	56.683	Down-regulation
CAMK_CAMKL_AMPK_PRKAA1_ST	P36956	SREBF1	Q13131	PRKAA1	S455	P459L	459	Missense	distal	4	no	51.245	57.984	EPSD	TCGA	56.683	Gain
CAMK_CAMKL_AMPK_PRKAA1_ST	Q09472	EP300	Q13131	PRKAA1	S28	A25P	25	Missense	distal	-3	no	56.080	58.077	EPSD	TCGA;ICGC;COSMIC	56.683	Gain
CAMK_CAMKL_AMPK_PRKAA1_ST	Q09472	EP300	Q13131	PRKAA1	S89	N94S	94	Missense	distal	5	no	74.231	74.268	PhosphoSitePlus	TCGA;ICGC;COSMIC	56.683	Up-regulation
CAMK_CAMKL_AMPK_PRKAA1_ST	Q09472	EP300	Q13131	PRKAA1	S89	L84S	84	Missense	distal	-5	no	74.231	70.049	PhosphoSitePlus	TCGA;COSMIC	56.683	Down-regulation
CAMK_CAMKL_AMPK_PRKAA1_ST	Q09472	EP300	Q13131	PRKAA1	S89	R86Q	86	Missense	distal	-3	no	74.231	66.287	PhosphoSitePlus	TCGA;ICGC	56.683	Down-regulation
CAMK_CAMKL_AMPK_PRKAA1_ST	Q09472	EP300	Q13131	PRKAA1	S1016	S1009Y	1009	Missense	distal	-7	no	61.915	59.776	EPSD	TCGA;ICGC;COSMIC	56.683	Down-regulation
CAMK_CAMKL_AMPK_PRKAA1_ST	Q09472	EP300	Q13131	PRKAA1	T1190	D1188H	1188	Missense	proximal	-2	no	62.566	60.317	EPSD	TCGA;ICGC;COSMIC	56.683	Down-regulation
CAMK_CAMKL_AMPK_PRKAA1_ST	Q09472	EP300	Q13131	PRKAA1	T1190	I1185V	1185	Missense	distal	-5	no	62.566	57.124	EPSD	TCGA;COSMIC	56.683	Down-regulation
CAMK_CAMKL_AMPK_PRKAA1_ST	Q09472	EP300	Q13131	PRKAA1	T1190	A1189V	1189	Missense	proximal	-1	no	62.566	62.475	EPSD	TCGA;ICGC;COSMIC	56.683	Down-regulation
CAMK_CAMKL_AMPK_PRKAA1_ST	Q09472	EP300	Q13131	PRKAA1	S1534	E1536D	1536	Missense	proximal	2	no	58.344	58.383	EPSD	TCGA;ICGC;COSMIC	56.683	Up-regulation
CAMK_CAMKL_AMPK_PRKAA1_ST	Q09472	EP300	Q13131	PRKAA1	S1534	E1536Q	1536	Missense	proximal	2	no	58.344	57.358	EPSD	TCGA;ICGC;COSMIC	56.683	Down-regulation
CAMK_CAMKL_AMPK_PRKAA1_ST	Q09472	EP300	Q13131	PRKAA1	S1577	S1581L	1581	Missense	distal	4	no	51.425	58.013	EPSD	TCGA;ICGC;COSMIC	56.683	Gain
CAMK_CAMKL_AMPK_PRKAA1_ST	Q09472	EP300	Q13131	PRKAA1	S1834	R1829C	1829	Missense	distal	-5	no	58.929	57.575	EPSD	TCGA;ICGC;COSMIC	56.683	Down-regulation
CAMK_CAMKL_AMPK_PRKAA1_ST	Q09472	EP300	Q13131	PRKAA1	S1834	R1830S	1830	Missense	distal	-4	no	58.929	57.865	EPSD	TCGA;ICGC;COSMIC	56.683	Down-regulation
CAMK_CAMKL_AMPK_PRKAA1_ST	Q09472	EP300	Q13131	PRKAA1	S1834	L1828F	1828	Missense	distal	-6	no	58.929	58.721	EPSD	TCGA;ICGC;COSMIC	56.683	Down-regulation
CAMK_CAMKL_AMPK_PRKAA1_ST	Q09472	EP300	Q13131	PRKAA1	S1849	Q1843P	1843	Missense	distal	-6	no	59.898	59.419	EPSD	TCGA;ICGC;COSMIC	56.683	Down-regulation
CAMK_CAMKL_AMPK_PRKAA1_ST	Q09472	EP300	Q13131	PRKAA1	S1897	Q1904P	1904	Missense	distal	7	no	62.414	61.138	EPSD	TCGA;ICGC;COSMIC	56.683	Down-regulation
CAMK_CAMKL_AMPK_PRKAA1_ST	Q09472	EP300	Q13131	PRKAA1	S1897	A1901V	1901	Missense	distal	4	no	62.414	62.447	EPSD	TCGA;ICGC;COSMIC	56.683	Up-regulation
CAMK_CAMKL_AMPK_PRKAA1_ST	Q09472	EP300	Q13131	PRKAA1	S2325	P2327H	2327	Missense	proximal	2	no	59.282	59.127	EPSD	TCGA;ICGC	56.683	Down-regulation
CAMK_CAMKL_AMPK_PRKAA1_ST	Q86TI0	TBC1D1	Q13131	PRKAA1	S146	I147M	147	Missense	proximal	1	no	55.594	59.216	EPSD	TCGA;ICGC;COSMIC	56.683	Gain
CAMK_CAMKL_AMPK_PRKAA1_ST	Q86TI0	TBC1D1	Q13131	PRKAA1	S235	M232V	232	Missense	distal	-3	no	53.087	57.555	EPSD	TCGA;ICGC;COSMIC	56.683	Gain
CAMK_CAMKL_AMPK_PRKAA1_ST	Q86TI0	TBC1D1	Q13131	PRKAA1	S237	F236L	236	Missense	proximal	-1	no	63.626	63.698	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	56.683	Up-regulation
CAMK_CAMKL_AMPK_PRKAA1_ST	Q86TI0	TBC1D1	Q13131	PRKAA1	S237	G240S	240	Missense	distal	3	no	63.626	62.424	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	56.683	Down-regulation
CAMK_CAMKL_AMPK_PRKAA1_ST	Q86TI0	TBC1D1	Q13131	PRKAA1	S237	M232V	232	Missense	distal	-5	no	63.626	58.930	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	56.683	Down-regulation
CAMK_CAMKL_AMPK_PRKAA1_ST	Q86TI0	TBC1D1	Q13131	PRKAA1	S237	R233H	233	Missense	distal	-4	no	63.626	60.240	EPSD;PhosphoSitePlus	TCGA;ICGC	56.683	Down-regulation
CAMK_CAMKL_AMPK_PRKAA1_ST	Q86TI0	TBC1D1	Q13131	PRKAA1	S407	S407Y	407	Missense	central	0	yes	57.512	0.000	EPSD	TCGA;ICGC;COSMIC	56.683	Loss
CAMK_CAMKL_AMPK_PRKAA1_ST	Q86TI0	TBC1D1	Q13131	PRKAA1	S407	T410A	410	Missense	distal	3	no	57.512	54.597	EPSD	TCGA;ICGC;COSMIC	56.683	Loss
CAMK_CAMKL_AMPK_PRKAA1_ST	Q86TI0	TBC1D1	Q13131	PRKAA1	S407	E403D	403	Missense	distal	-4	no	57.512	57.473	EPSD	TCGA;ICGC;COSMIC	56.683	Down-regulation
CAMK_CAMKL_AMPK_PRKAA1_ST	Q86TI0	TBC1D1	Q13131	PRKAA1	S407	I402L	402	Missense	distal	-5	no	57.512	56.933	EPSD	TCGA;ICGC;COSMIC	56.683	Down-regulation
CAMK_CAMKL_AMPK_PRKAA1_ST	Q86TI0	TBC1D1	Q13131	PRKAA1	S513	R519K	519	Missense	distal	6	no	57.727	57.779	EPSD	TCGA;ICGC;COSMIC	56.683	Up-regulation
CAMK_CAMKL_AMPK_PRKAA1_ST	Q86TI0	TBC1D1	Q13131	PRKAA1	S513	R519G	519	Missense	distal	6	no	57.727	57.606	EPSD	TCGA;ICGC;COSMIC	56.683	Down-regulation
CAMK_CAMKL_AMPK_PRKAA1_ST	Q86TI0	TBC1D1	Q13131	PRKAA1	S513	R514Q	514	Missense	proximal	1	no	57.727	56.847	EPSD	TCGA;ICGC;COSMIC	56.683	Down-regulation
CAMK_CAMKL_AMPK_PRKAA1_ST	Q86TI0	TBC1D1	Q13131	PRKAA1	T596	E603K	603	Missense	distal	7	no	59.857	59.161	PhosphoSitePlus;EPSD	TCGA;ICGC;COSMIC	56.683	Down-regulation
CAMK_CAMKL_AMPK_PRKAA1_ST	Q86TI0	TBC1D1	Q13131	PRKAA1	T596	P601S	601	Missense	distal	5	no	59.857	59.818	PhosphoSitePlus;EPSD	TCGA;ICGC;COSMIC	56.683	Down-regulation
CAMK_CAMKL_AMPK_PRKAA1_ST	Q86TI0	TBC1D1	Q13131	PRKAA1	S598	E603K	603	Missense	distal	5	no	60.694	60.715	EPSD	TCGA;ICGC;COSMIC	56.683	Up-regulation
CAMK_CAMKL_AMPK_PRKAA1_ST	Q86TI0	TBC1D1	Q13131	PRKAA1	S598	P601S	601	Missense	distal	3	no	60.694	62.932	EPSD	TCGA;ICGC;COSMIC	56.683	Up-regulation
CAMK_CAMKL_AMPK_PRKAA1_ST	Q86TI0	TBC1D1	Q13131	PRKAA1	T1142	S1137L	1137	Missense	distal	-5	no	53.271	57.453	EPSD	TCGA;ICGC;COSMIC	56.683	Gain
CAMK_CAMKL_AMPK_PRKAA1_ST	Q9H3M7	TXNIP	Q13131	PRKAA1	S304	R305K	305	Missense	proximal	1	no	62.361	63.226	EPSD	TCGA;ICGC;COSMIC	56.683	Up-regulation
CAMK_CAMKL_AMPK_PRKAA1_ST	Q9H3M7	TXNIP	Q13131	PRKAA1	S308	R305K	305	Missense	distal	-3	no	62.136	57.495	PhosphoSitePlus	TCGA;ICGC;COSMIC	56.683	Down-regulation
CAMK_CAMKL_AMPK_PRKAA1_ST	Q9H3M7	TXNIP	Q13131	PRKAA1	S315	E316Q	316	Missense	proximal	1	no	61.575	60.759	EPSD	TCGA;ICGC;COSMIC	56.683	Down-regulation
CAMK_CAMKL_AMPK_PRKAA1_ST	Q9H3M7	TXNIP	Q13131	PRKAA1	S318	E316Q	316	Missense	proximal	-2	no	61.125	61.484	EPSD	TCGA;ICGC;COSMIC	56.683	Up-regulation
CAMK_CAMKL_AMPK_PRKAA1_ST	Q9H3M7	TXNIP	Q13131	PRKAA1	T349	P350H	350	Missense	proximal	1	no	55.772	58.416	EPSD	TCGA;ICGC;COSMIC	56.683	Gain
CAMK_CAMKL_AMPK_PRKAA1_ST	Q9H3M7	TXNIP	Q13131	PRKAA1	S361	P368H	368	Missense	distal	7	no	58.179	57.364	EPSD	TCGA;ICGC;COSMIC	56.683	Down-regulation
CAMK_CAMKL_AMPK_PRKAA1_ST	Q07866	KLC1	Q13131	PRKAA1	S521	E523D	523	Missense	proximal	2	no	59.065	59.105	PhosphoSitePlus	TCGA;ICGC;COSMIC	56.683	Up-regulation
CAMK_CAMKL_AMPK_PRKAA1_ST	Q07866	KLC1	Q13131	PRKAA1	S521	V527M	527	Missense	distal	6	no	59.065	59.284	PhosphoSitePlus	TCGA;ICGC;COSMIC;CCLE	56.683	Up-regulation
CAMK_CAMKL_AMPK_PRKAA1_ST	Q07866	KLC1	Q13131	PRKAA1	S521	R519C	519	Missense	proximal	-2	no	59.065	51.954	PhosphoSitePlus	TCGA;ICGC	56.683	Loss
CAMK_CAMKL_AMPK_PRKAA1_ST	Q07866	KLC1	Q13131	PRKAA1	S521	R519H	519	Missense	proximal	-2	no	59.065	56.344	PhosphoSitePlus	TCGA;ICGC;COSMIC	56.683	Loss
CAMK_CAMKL_AMPK_PRKAA1_ST	Q07866	KLC1	Q13131	PRKAA1	S524	E523D	523	Missense	proximal	-1	no	60.598	60.679	EPSD	TCGA;ICGC;COSMIC	56.683	Up-regulation
CAMK_CAMKL_AMPK_PRKAA1_ST	Q07866	KLC1	Q13131	PRKAA1	S524	V527M	527	Missense	distal	3	no	60.598	55.990	EPSD	TCGA;ICGC;COSMIC;CCLE	56.683	Loss
CAMK_CAMKL_AMPK_PRKAA1_ST	Q07866	KLC1	Q13131	PRKAA1	S524	R519C	519	Missense	distal	-5	no	60.598	59.244	EPSD	TCGA;ICGC	56.683	Down-regulation
CAMK_CAMKL_AMPK_PRKAA1_ST	Q07866	KLC1	Q13131	PRKAA1	S524	R519H	519	Missense	distal	-5	no	60.598	55.217	EPSD	TCGA;ICGC;COSMIC	56.683	Loss
CAMK_CAMKL_AMPK_PRKAA1_ST	P26358	DNMT1	Q13131	PRKAA1	S91	S84C	84	Missense	distal	-7	no	58.809	56.421	EPSD	TCGA;ICGC;COSMIC	56.683	Loss
CAMK_CAMKL_AMPK_PRKAA1_ST	P26358	DNMT1	Q13131	PRKAA1	S91	D89Y	89	Missense	proximal	-2	no	58.809	58.959	EPSD	TCGA;ICGC	56.683	Up-regulation
CAMK_CAMKL_AMPK_PRKAA1_ST	P26358	DNMT1	Q13131	PRKAA1	S91	E93V	93	Missense	proximal	2	no	58.809	59.152	EPSD	TCGA;ICGC;COSMIC	56.683	Up-regulation
CAMK_CAMKL_AMPK_PRKAA1_ST	P26358	DNMT1	Q13131	PRKAA1	S714	M712I	712	Missense	proximal	-2	no	62.342	62.878	EPSD	TCGA;ICGC;COSMIC	56.683	Up-regulation
CAMK_CAMKL_AMPK_PRKAA1_ST	Q00613	HSF1	Q13131	PRKAA1	T120	L125M	125	Missense	distal	5	no	65.215	65.038	EPSD	TCGA;COSMIC	56.683	Down-regulation
CAMK_CAMKL_AMPK_PRKAA1_ST	Q00613	HSF1	Q13131	PRKAA1	S121	E128K	128	Missense	distal	7	no	61.132	60.435	PhosphoSitePlus	TCGA;COSMIC	56.683	Down-regulation
CAMK_CAMKL_AMPK_PRKAA1_ST	Q00613	HSF1	Q13131	PRKAA1	S121	L125M	125	Missense	distal	4	no	61.132	58.555	PhosphoSitePlus	TCGA;COSMIC	56.683	Down-regulation
CAMK_CAMKL_AMPK_PRKAA1_ST	Q00613	HSF1	Q13131	PRKAA1	S136	R133H	133	Missense	distal	-3	no	65.929	58.073	EPSD	TCGA;COSMIC	56.683	Down-regulation
CAMK_CAMKL_AMPK_PRKAA1_ST	Q00613	HSF1	Q13131	PRKAA1	S136	I130V	130	Missense	distal	-6	no	65.929	67.420	EPSD	TCGA;COSMIC	56.683	Up-regulation
CAMK_CAMKL_AMPK_PRKAA1_ST	Q00613	HSF1	Q13131	PRKAA1	S244	S250C	250	Missense	distal	6	no	59.384	59.608	EPSD	TCGA;COSMIC	56.683	Up-regulation
CAMK_CAMKL_AMPK_PRKAA1_ST	Q00613	HSF1	Q13131	PRKAA1	S248	S250C	250	Missense	proximal	2	no	58.601	57.304	EPSD	TCGA;COSMIC	56.683	Down-regulation
CAMK_CAMKL_AMPK_PRKAA1_ST	Q00613	HSF1	Q13131	PRKAA1	S248	A254T	254	Missense	distal	6	no	58.601	58.441	EPSD	TCGA;COSMIC;CCLE	56.683	Down-regulation
CAMK_CAMKL_AMPK_PRKAA1_ST	Q00613	HSF1	Q13131	PRKAA1	S290	R296C	296	Missense	distal	6	no	68.858	69.188	EPSD	TCGA;COSMIC	56.683	Up-regulation
CAMK_CAMKL_AMPK_PRKAA1_ST	Q00613	HSF1	Q13131	PRKAA1	S290	P288L	288	Missense	proximal	-2	no	68.858	65.883	EPSD	TCGA;COSMIC	56.683	Down-regulation
CAMK_CAMKL_AMPK_PRKAA1_ST	Q00613	HSF1	Q13131	PRKAA1	S290	E286K	286	Missense	distal	-4	no	68.858	65.732	EPSD	TCGA;COSMIC	56.683	Down-regulation
CAMK_CAMKL_AMPK_PRKAA1_ST	Q00613	HSF1	Q13131	PRKAA1	S320	R317H	317	Missense	distal	-3	no	66.156	58.299	EPSD	TCGA;COSMIC	56.683	Down-regulation
CAMK_CAMKL_AMPK_PRKAA1_ST	Q00613	HSF1	Q13131	PRKAA1	S320	T323I	323	Missense	distal	3	no	66.156	64.843	EPSD	TCGA;COSMIC	56.683	Down-regulation
CAMK_CAMKL_AMPK_PRKAA1_ST	Q00613	HSF1	Q13131	PRKAA1	S320	S320F	320	Missense	central	0	yes	66.156	0.000	EPSD	TCGA;COSMIC	56.683	Loss
CAMK_CAMKL_AMPK_PRKAA1_ST	Q00613	HSF1	Q13131	PRKAA1	S320	P327L	327	Missense	distal	7	no	66.156	66.696	EPSD	TCGA	56.683	Up-regulation
CAMK_CAMKL_AMPK_PRKAA1_ST	Q00613	HSF1	Q13131	PRKAA1	S363	P364S	364	Missense	proximal	1	no	58.558	59.191	EPSD	TCGA;COSMIC	56.683	Up-regulation
CAMK_CAMKL_AMPK_PRKAA1_ST	Q00613	HSF1	Q13131	PRKAA1	S438	E441K	441	Missense	distal	3	no	60.281	62.006	EPSD	TCGA;COSMIC	56.683	Up-regulation
CAMK_CAMKL_AMPK_PRKAA1_ST	Q16875	PFKFB3	Q13131	PRKAA1	T36	V37I	37	Missense	proximal	1	no	64.333	62.890	EPSD	TCGA;COSMIC	56.683	Down-regulation
CAMK_CAMKL_AMPK_PRKAA1_ST	Q16875	PFKFB3	Q13131	PRKAA1	S83	R89C	89	Missense	distal	6	no	66.571	66.902	EPSD	TCGA;COSMIC	56.683	Up-regulation
CAMK_CAMKL_AMPK_PRKAA1_ST	Q16875	PFKFB3	Q13131	PRKAA1	S83	F87L	87	Missense	distal	4	no	66.571	70.766	EPSD	TCGA;COSMIC;GDSC;CCLE	56.683	Up-regulation
CAMK_CAMKL_AMPK_PRKAA1_ST	Q16875	PFKFB3	Q13131	PRKAA1	S211	R208G	208	Missense	distal	-3	no	63.029	53.994	EPSD	TCGA;COSMIC	56.683	Loss
CAMK_CAMKL_AMPK_PRKAA1_ST	Q16875	PFKFB3	Q13131	PRKAA1	S211	V218M	218	Missense	distal	7	no	63.029	63.357	EPSD	TCGA;ICGC;COSMIC	56.683	Up-regulation
CAMK_CAMKL_AMPK_PRKAA1_ST	Q16875	PFKFB3	Q13131	PRKAA1	S461	S461C	461	Missense	central	0	yes	63.780	0.000	PhosphoSitePlus	TCGA;COSMIC	56.683	Loss
CAMK_CAMKL_AMPK_PRKAA1_ST	Q16875	PFKFB3	Q13131	PRKAA1	S461	P464L	464	Missense	distal	3	no	63.780	64.036	PhosphoSitePlus	TCGA;COSMIC	56.683	Up-regulation
CAMK_CAMKL_AMPK_PRKAA1_ST	Q16875	PFKFB3	Q13131	PRKAA1	S461	N460Y	460	Missense	proximal	-1	no	63.780	63.934	PhosphoSitePlus	TCGA;COSMIC	56.683	Up-regulation
CAMK_CAMKL_AMPK_PRKAA1_ST	Q9P2M7	CGN	Q13131	PRKAA1	S43	R41H	41	Missense	proximal	-2	no	56.945	54.224	EPSD	TCGA;ICGC;COSMIC	56.683	Loss
CAMK_CAMKL_AMPK_PRKAA1_ST	Q8IXJ6	SIRT2	Q13131	PRKAA1	S100	D95N	95	Missense	distal	-5	no	56.799	42.724	EPSD	TCGA	56.683	Loss
CAMK_CAMKL_AMPK_PRKAA1_ST	Q8IXJ6	SIRT2	Q13131	PRKAA1	T101	D95N	95	Missense	distal	-6	no	58.596	56.331	PhosphoSitePlus	TCGA	56.683	Loss
CAMK_CAMKL_AMPK_PRKAA1_ST	Q13363	CTBP1	Q13131	PRKAA1	S100	D106N	106	Missense	distal	6	no	58.947	59.129	EPSD	TCGA;GDSC;CCLE	56.683	Up-regulation
CAMK_CAMKL_AMPK_PRKAA1_ST	Q13363	CTBP1	Q13131	PRKAA1	S100	R97W	97	Missense	distal	-3	no	58.947	-34.053	EPSD	TCGA;COSMIC	56.683	Loss
CAMK_CAMKL_AMPK_PRKAA1_ST	Q13363	CTBP1	Q13131	PRKAA1	S100	R93H	93	Missense	distal	-7	no	58.947	55.923	EPSD	TCGA;COSMIC	56.683	Loss
CAMK_CAMKL_AMPK_PRKAA1_ST	Q13363	CTBP1	Q13131	PRKAA1	S100	V96I	96	Missense	distal	-4	no	58.947	57.541	EPSD	TCGA	56.683	Down-regulation
CAMK_CAMKL_AMPK_PRKAA1_ST	Q13363	CTBP1	Q13131	PRKAA1	S158	R155Q	155	Missense	distal	-3	no	62.373	54.429	PhosphoSitePlus	TCGA	56.683	Loss
CAMK_CAMKL_AMPK_PRKAA1_ST	Q14247	CTTN	Q13131	PRKAA1	S113	G120V	120	Missense	distal	7	no	59.382	57.143	EPSD	TCGA;ICGC;COSMIC	56.683	Down-regulation
CAMK_CAMKL_AMPK_PRKAA1_ST	Q14247	CTTN	Q13131	PRKAA1	S113	Q114P	114	Missense	proximal	1	no	59.382	60.616	EPSD	TCGA;ICGC;COSMIC	56.683	Up-regulation
CAMK_CAMKL_AMPK_PRKAA1_ST	Q14247	CTTN	Q13131	PRKAA1	S113	S113L	113	Missense	central	0	yes	59.382	0.000	EPSD	TCGA;ICGC;COSMIC;GDSC;CCLE	56.683	Loss
CAMK_CAMKL_AMPK_PRKAA1_ST	Q14247	CTTN	Q13131	PRKAA1	S224	T219M	219	Missense	distal	-5	no	52.093	57.589	EPSD	TCGA;ICGC;COSMIC	56.683	Gain
CAMK_CAMKL_AMPK_PRKAA1_ST	Q14247	CTTN	Q13131	PRKAA1	S282	A284V	284	Missense	proximal	2	no	65.321	66.467	EPSD	TCGA;COSMIC;CCLE	56.683	Up-regulation
CAMK_CAMKL_AMPK_PRKAA1_ST	Q9NZQ7	CD274	Q13131	PRKAA1	S279	D276H	276	Missense	distal	-3	no	62.501	64.497	EPSD	TCGA;COSMIC	56.683	Up-regulation
CAMK_CAMKL_AMPK_PRKAA1_ST	Q9NZQ7	CD274	Q13131	PRKAA1	S279	K280N	280	Missense	proximal	1	no	62.501	61.768	EPSD	TCGA;COSMIC	56.683	Down-regulation
CAMK_CAMKL_AMPK_PRKAA1_ST	Q9NZQ7	CD274	Q13131	PRKAA1	S279	T277S	277	Missense	proximal	-2	no	62.501	65.184	EPSD	TCGA;COSMIC	56.683	Up-regulation
CAMK_CAMKL_AMPK_PRKAA1_ST	P15056	BRAF	Q13131	PRKAA1	S151	R146W	146	Missense	distal	-5	no	59.762	54.569	EPSD	TCGA;ICGC;COSMIC	56.683	Loss
CAMK_CAMKL_AMPK_PRKAA1_ST	P15056	BRAF	Q13131	PRKAA1	S314	P318L	318	Missense	distal	4	no	49.994	56.734	EPSD	TCGA;ICGC;COSMIC	56.683	Gain
CAMK_CAMKL_AMPK_PRKAA1_ST	P15056	BRAF	Q13131	PRKAA1	S363	S364L	364	Missense	proximal	1	no	60.159	59.234	EPSD	TCGA;ICGC;COSMIC	56.683	Down-regulation
CAMK_CAMKL_AMPK_PRKAA1_ST	P15056	BRAF	Q13131	PRKAA1	S363	P367R	367	Missense	distal	4	no	60.159	61.417	EPSD	TCGA;ICGC;COSMIC	56.683	Up-regulation
CAMK_CAMKL_AMPK_PRKAA1_ST	P15056	BRAF	Q13131	PRKAA1	S363	P367S	367	Missense	distal	4	no	60.159	60.311	EPSD	TCGA;ICGC;COSMIC	56.683	Up-regulation
CAMK_CAMKL_AMPK_PRKAA1_ST	P15056	BRAF	Q13131	PRKAA1	S365	S364L	364	Missense	proximal	-1	no	71.119	71.145	EPSD	TCGA;ICGC;COSMIC	56.683	Up-regulation
CAMK_CAMKL_AMPK_PRKAA1_ST	P15056	BRAF	Q13131	PRKAA1	S365	P367R	367	Missense	proximal	2	no	71.119	70.669	EPSD	TCGA;ICGC;COSMIC	56.683	Down-regulation
CAMK_CAMKL_AMPK_PRKAA1_ST	P15056	BRAF	Q13131	PRKAA1	S365	P367S	367	Missense	proximal	2	no	71.119	70.576	EPSD	TCGA;ICGC;COSMIC	56.683	Down-regulation
CAMK_CAMKL_AMPK_PRKAA1_ST	P15056	BRAF	Q13131	PRKAA1	S429	E433K	433	Missense	distal	4	no	54.233	59.989	EPSD	TCGA;ICGC;COSMIC	56.683	Gain
CAMK_CAMKL_AMPK_PRKAA1_ST	P15056	BRAF	Q13131	PRKAA1	S430	E433K	433	Missense	distal	3	no	63.157	64.881	EPSD	TCGA;ICGC;COSMIC	56.683	Up-regulation
CAMK_CAMKL_AMPK_PRKAA1_ST	P15056	BRAF	Q13131	PRKAA1	T440	E433K	433	Missense	distal	-7	no	58.124	59.517	EPSD	TCGA;ICGC;COSMIC	56.683	Up-regulation
CAMK_CAMKL_AMPK_PRKAA1_ST	P15056	BRAF	Q13131	PRKAA1	S446	E451G	451	Missense	distal	5	no	72.355	72.357	EPSD	TCGA;ICGC;COSMIC	56.683	Up-regulation
CAMK_CAMKL_AMPK_PRKAA1_ST	P15056	BRAF	Q13131	PRKAA1	S446	D449N	449	Missense	distal	3	no	72.355	73.609	EPSD	TCGA;ICGC;COSMIC	56.683	Up-regulation
CAMK_CAMKL_AMPK_PRKAA1_ST	P15056	BRAF	Q13131	PRKAA1	S447	E451G	451	Missense	distal	4	no	63.427	66.985	EPSD	TCGA;ICGC;COSMIC	56.683	Up-regulation
CAMK_CAMKL_AMPK_PRKAA1_ST	P15056	BRAF	Q13131	PRKAA1	S447	D449N	449	Missense	proximal	2	no	63.427	62.541	EPSD	TCGA;ICGC;COSMIC	56.683	Down-regulation
CAMK_CAMKL_AMPK_PRKAA1_ST	P15056	BRAF	Q13131	PRKAA1	S465	G469A	469	Missense	distal	4	no	55.618	58.771	EPSD	TCGA;ICGC;COSMIC;GDSC;CCLE	56.683	Gain
CAMK_CAMKL_AMPK_PRKAA1_ST	P15056	BRAF	Q13131	PRKAA1	S465	G469V	469	Missense	distal	4	no	55.618	58.804	EPSD	TCGA;ICGC;COSMIC;GDSC;CCLE	56.683	Gain
CAMK_CAMKL_AMPK_PRKAA1_ST	P15056	BRAF	Q13131	PRKAA1	S465	G469R	469	Missense	distal	4	no	55.618	57.820	EPSD	TCGA;ICGC;COSMIC	56.683	Gain
CAMK_CAMKL_AMPK_PRKAA1_ST	P15056	BRAF	Q13131	PRKAA1	S614	Q609E	609	Missense	distal	-5	no	54.769	60.009	EPSD	TCGA;ICGC;COSMIC	56.683	Gain
CAMK_CAMKL_AMPK_PRKAA1_ST	P15056	BRAF	Q13131	PRKAA1	S616	Q609E	609	Missense	distal	-7	no	63.466	63.499	EPSD	TCGA;ICGC;COSMIC	56.683	Up-regulation
CAMK_CAMKL_AMPK_PRKAA1_ST	P15056	BRAF	Q13131	PRKAA1	S616	L613F	613	Missense	distal	-3	no	63.466	64.185	EPSD	TCGA;ICGC;COSMIC	56.683	Up-regulation
CAMK_CAMKL_AMPK_PRKAA1_ST	P15056	BRAF	Q13131	PRKAA1	S616	Q609H	609	Missense	distal	-7	no	63.466	60.265	EPSD	TCGA;ICGC;COSMIC	56.683	Down-regulation
CAMK_CAMKL_AMPK_PRKAA1_ST	P15056	BRAF	Q13131	PRKAA1	S616	S614P	614	Missense	proximal	-2	no	63.466	64.015	EPSD	TCGA;ICGC;COSMIC	56.683	Up-regulation
CAMK_CAMKL_AMPK_PRKAA1_ST	P15056	BRAF	Q13131	PRKAA1	S720	H725Y	725	Missense	distal	5	no	61.501	61.746	EPSD	TCGA;ICGC;COSMIC	56.683	Up-regulation
CAMK_CAMKL_AMPK_PRKAA1_ST	P15056	BRAF	Q13131	PRKAA1	S720	R726C	726	Missense	distal	6	no	61.501	61.831	EPSD	TCGA;ICGC;COSMIC;GDSC;CCLE	56.683	Up-regulation
CAMK_CAMKL_AMPK_PRKAA1_ST	P15056	BRAF	Q13131	PRKAA1	S729	L733F	733	Missense	distal	4	no	73.936	69.741	PhosphoSitePlus	TCGA;ICGC;COSMIC	56.683	Down-regulation
CAMK_CAMKL_AMPK_PRKAA1_ST	P15056	BRAF	Q13131	PRKAA1	S729	H725Y	725	Missense	distal	-4	no	73.936	73.397	PhosphoSitePlus	TCGA;ICGC;COSMIC	56.683	Down-regulation
CAMK_CAMKL_AMPK_PRKAA1_ST	P15056	BRAF	Q13131	PRKAA1	S729	R726C	726	Missense	distal	-3	no	73.936	59.788	PhosphoSitePlus	TCGA;ICGC;COSMIC;GDSC;CCLE	56.683	Down-regulation
CAMK_CAMKL_AMPK_PRKAA1_ST	P15056	BRAF	Q13131	PRKAA1	S729	P731S	731	Missense	proximal	2	no	73.936	73.392	PhosphoSitePlus	TCGA;ICGC;COSMIC	56.683	Down-regulation
CAMK_CAMKL_AMPK_PRKAA1_ST	P15056	BRAF	Q13131	PRKAA1	S729	R735W	735	Missense	distal	6	no	73.936	73.446	PhosphoSitePlus	TCGA;ICGC;COSMIC	56.683	Down-regulation
CAMK_CAMKL_AMPK_PRKAA1_ST	P15056	BRAF	Q13131	PRKAA1	S729	N734S	734	Missense	distal	5	no	73.936	73.973	PhosphoSitePlus	TCGA;ICGC;COSMIC	56.683	Up-regulation
CAMK_CAMKL_AMPK_PRKAA1_ST	O14929	HAT1	Q13131	PRKAA1	S190	W184R	184	Missense	distal	-6	no	53.288	58.100	PhosphoSitePlus	TCGA;ICGC;COSMIC	56.683	Gain
CAMK_CAMKL_AMPK_PRKAA1_ST	O14929	HAT1	Q13131	PRKAA1	S301	R302Q	302	Missense	proximal	1	no	61.163	60.284	EPSD	TCGA;ICGC;COSMIC	56.683	Down-regulation
CAMK_CAMKL_AMPK_PRKAA1_ST	O14929	HAT1	Q13131	PRKAA1	S301	K304I	304	Missense	distal	3	no	61.163	58.030	EPSD	TCGA;ICGC;COSMIC	56.683	Down-regulation
CAMK_CAMKL_AMPK_PRKAA1_ST	O14929	HAT1	Q13131	PRKAA1	S301	S301F	301	Missense	central	0	yes	61.163	0.000	EPSD	TCGA;ICGC;COSMIC	56.683	Loss
CAMK_CAMKL_AMPK_PRKAA1_ST	O14929	HAT1	Q13131	PRKAA1	S301	L305S	305	Missense	distal	4	no	61.163	54.576	EPSD	TCGA;ICGC;COSMIC;GDSC;CCLE	56.683	Loss
CAMK_CAMKL_AMPK_PRKAA1_ST	Q12778	FOXO1	Q13131	PRKAA1	S22	S22W	22	Missense	central	0	yes	62.002	0.000	EPSD	TCGA;ICGC;COSMIC;CCLE	56.683	Loss
CAMK_CAMKL_AMPK_PRKAA1_ST	Q12778	FOXO1	Q13131	PRKAA1	T24	S22W	22	Missense	proximal	-2	no	60.529	56.950	EPSD	TCGA;ICGC;COSMIC;CCLE	56.683	Down-regulation
CAMK_CAMKL_AMPK_PRKAA1_ST	Q12778	FOXO1	Q13131	PRKAA1	S205	W209C	209	Missense	distal	4	no	57.171	33.066	EPSD	TCGA;ICGC;COSMIC	56.683	Loss
CAMK_CAMKL_AMPK_PRKAA1_ST	Q12778	FOXO1	Q13131	PRKAA1	S218	R214H	214	Missense	distal	-4	no	57.131	53.745	EPSD	TCGA;ICGC;COSMIC	56.683	Loss
CAMK_CAMKL_AMPK_PRKAA1_ST	Q12778	FOXO1	Q13131	PRKAA1	S218	R225C	225	Missense	distal	7	no	57.131	57.164	EPSD	TCGA;ICGC;COSMIC	56.683	Up-regulation
CAMK_CAMKL_AMPK_PRKAA1_ST	Q12778	FOXO1	Q13131	PRKAA1	S218	R225H	225	Missense	distal	7	no	57.131	56.405	EPSD	TCGA;ICGC;COSMIC;GDSC;CCLE	56.683	Loss
CAMK_CAMKL_AMPK_PRKAA1_ST	Q12778	FOXO1	Q13131	PRKAA1	S218	R214C	214	Missense	distal	-4	no	57.131	61.442	EPSD	TCGA;ICGC;COSMIC	56.683	Up-regulation
CAMK_CAMKL_AMPK_PRKAA1_ST	Q12778	FOXO1	Q13131	PRKAA1	S256	A255T	255	Missense	proximal	-1	no	64.482	64.403	EPSD	TCGA;ICGC;COSMIC	56.683	Down-regulation
CAMK_CAMKL_AMPK_PRKAA1_ST	Q12778	FOXO1	Q13131	PRKAA1	S256	R251S	251	Missense	distal	-5	no	64.482	61.477	EPSD	TCGA;ICGC;COSMIC	56.683	Down-regulation
CAMK_CAMKL_AMPK_PRKAA1_ST	Q12778	FOXO1	Q13131	PRKAA1	S256	P250L	250	Missense	distal	-6	no	64.482	64.443	EPSD	TCGA;ICGC;COSMIC	56.683	Down-regulation
CAMK_CAMKL_AMPK_PRKAA1_ST	Q12778	FOXO1	Q13131	PRKAA1	S256	P250S	250	Missense	distal	-6	no	64.482	64.132	EPSD	TCGA;ICGC;COSMIC	56.683	Down-regulation
CAMK_CAMKL_AMPK_PRKAA1_ST	Q12778	FOXO1	Q13131	PRKAA1	S256	N260S	260	Missense	distal	4	no	64.482	65.953	EPSD	TCGA;ICGC;COSMIC	56.683	Up-regulation
CAMK_CAMKL_AMPK_PRKAA1_ST	Q12778	FOXO1	Q13131	PRKAA1	S256	S249Y	249	Missense	distal	-7	no	64.482	62.344	EPSD	TCGA;ICGC;COSMIC	56.683	Down-regulation
CAMK_CAMKL_AMPK_PRKAA1_ST	Q12778	FOXO1	Q13131	PRKAA1	T317	R314C	314	Missense	distal	-3	no	62.020	47.873	EPSD	TCGA;ICGC;COSMIC	56.683	Loss
CAMK_CAMKL_AMPK_PRKAA1_ST	Q12778	FOXO1	Q13131	PRKAA1	T317	W310L	310	Missense	distal	-7	no	62.020	58.789	EPSD	TCGA;ICGC;COSMIC	56.683	Down-regulation
CAMK_CAMKL_AMPK_PRKAA1_ST	Q12778	FOXO1	Q13131	PRKAA1	T317	R314H	314	Missense	distal	-3	no	62.020	54.164	EPSD	TCGA;ICGC;COSMIC	56.683	Loss
CAMK_CAMKL_AMPK_PRKAA1_ST	Q12778	FOXO1	Q13131	PRKAA1	T317	T323A	323	Missense	distal	6	no	62.020	62.180	EPSD	TCGA;ICGC;COSMIC	56.683	Up-regulation
CAMK_CAMKL_AMPK_PRKAA1_ST	Q12778	FOXO1	Q13131	PRKAA1	T317	F313V	313	Missense	distal	-4	no	62.020	62.474	EPSD	TCGA;ICGC	56.683	Up-regulation
CAMK_CAMKL_AMPK_PRKAA1_ST	Q12778	FOXO1	Q13131	PRKAA1	T317	R316Q	316	Missense	proximal	-1	no	62.020	62.049	EPSD	TCGA;ICGC;COSMIC	56.683	Up-regulation
CAMK_CAMKL_AMPK_PRKAA1_ST	Q12778	FOXO1	Q13131	PRKAA1	S319	R314C	314	Missense	distal	-5	no	64.829	63.475	EPSD	TCGA;ICGC;COSMIC	56.683	Down-regulation
CAMK_CAMKL_AMPK_PRKAA1_ST	Q12778	FOXO1	Q13131	PRKAA1	S319	G326R	326	Missense	distal	7	no	64.829	64.294	EPSD	TCGA;ICGC;COSMIC	56.683	Down-regulation
CAMK_CAMKL_AMPK_PRKAA1_ST	Q12778	FOXO1	Q13131	PRKAA1	S319	R314H	314	Missense	distal	-5	no	64.829	59.449	EPSD	TCGA;ICGC;COSMIC	56.683	Down-regulation
CAMK_CAMKL_AMPK_PRKAA1_ST	Q12778	FOXO1	Q13131	PRKAA1	S319	T323A	323	Missense	distal	4	no	64.829	67.398	EPSD	TCGA;ICGC;COSMIC	56.683	Up-regulation
CAMK_CAMKL_AMPK_PRKAA1_ST	Q12778	FOXO1	Q13131	PRKAA1	S319	F313V	313	Missense	distal	-6	no	64.829	63.544	EPSD	TCGA;ICGC	56.683	Down-regulation
CAMK_CAMKL_AMPK_PRKAA1_ST	Q12778	FOXO1	Q13131	PRKAA1	S319	R316Q	316	Missense	distal	-3	no	64.829	56.885	EPSD	TCGA;ICGC;COSMIC	56.683	Down-regulation
CAMK_CAMKL_AMPK_PRKAA1_ST	Q12778	FOXO1	Q13131	PRKAA1	S329	M332I	332	Missense	distal	3	no	59.724	61.057	EPSD	TCGA;COSMIC	56.683	Up-regulation
CAMK_CAMKL_AMPK_PRKAA1_ST	Q12778	FOXO1	Q13131	PRKAA1	S329	G326R	326	Missense	distal	-3	no	59.724	68.759	EPSD	TCGA;ICGC;COSMIC	56.683	Up-regulation
CAMK_CAMKL_AMPK_PRKAA1_ST	Q12778	FOXO1	Q13131	PRKAA1	S329	S329L	329	Missense	central	0	yes	59.724	0.000	EPSD	TCGA;ICGC;COSMIC	56.683	Loss
CAMK_CAMKL_AMPK_PRKAA1_ST	Q12778	FOXO1	Q13131	PRKAA1	S329	T323A	323	Missense	distal	-6	no	59.724	59.927	EPSD	TCGA;ICGC;COSMIC	56.683	Up-regulation
CAMK_CAMKL_AMPK_PRKAA1_ST	Q12778	FOXO1	Q13131	PRKAA1	T333	M332I	332	Missense	proximal	-1	no	60.509	60.506	EPSD	TCGA;COSMIC	56.683	Down-regulation
CAMK_CAMKL_AMPK_PRKAA1_ST	Q12778	FOXO1	Q13131	PRKAA1	T333	G326R	326	Missense	distal	-7	no	60.509	59.093	EPSD	TCGA;ICGC;COSMIC	56.683	Down-regulation
CAMK_CAMKL_AMPK_PRKAA1_ST	Q12778	FOXO1	Q13131	PRKAA1	T333	S329L	329	Missense	distal	-4	no	60.509	59.014	EPSD	TCGA;ICGC;COSMIC	56.683	Down-regulation
CAMK_CAMKL_AMPK_PRKAA1_ST	P43405	SYK	Q13131	PRKAA1	S93	A86T	86	Missense	distal	-7	no	55.925	56.774	EPSD	TCGA;ICGC;GDSC;CCLE	56.683	Gain
CAMK_CAMKL_AMPK_PRKAA1_ST	P43405	SYK	Q13131	PRKAA1	S295	G288R	288	Missense	distal	-7	no	60.446	59.031	EPSD	TCGA;ICGC;COSMIC	56.683	Down-regulation
CAMK_CAMKL_AMPK_PRKAA1_ST	P43405	SYK	Q13131	PRKAA1	S295	I289M	289	Missense	distal	-6	no	60.446	62.279	EPSD	TCGA;ICGC;COSMIC	56.683	Up-regulation
CAMK_CAMKL_AMPK_PRKAA1_ST	P43405	SYK	Q13131	PRKAA1	S295	S297C	297	Missense	proximal	2	no	60.446	59.149	EPSD	TCGA;ICGC;COSMIC	56.683	Down-regulation
CAMK_CAMKL_AMPK_PRKAA1_ST	P43405	SYK	Q13131	PRKAA1	S295	G288E	288	Missense	distal	-7	no	60.446	59.241	EPSD	TCGA;ICGC;COSMIC	56.683	Down-regulation
CAMK_CAMKL_AMPK_PRKAA1_ST	P43405	SYK	Q13131	PRKAA1	S295	R292I	292	Missense	distal	-3	no	60.446	47.048	EPSD	TCGA;ICGC	56.683	Loss
CAMK_CAMKL_AMPK_PRKAA1_ST	P43405	SYK	Q13131	PRKAA1	S297	S297C	297	Missense	central	0	yes	61.680	0.000	EPSD	TCGA;ICGC;COSMIC	56.683	Loss
CAMK_CAMKL_AMPK_PRKAA1_ST	P43405	SYK	Q13131	PRKAA1	S297	R292I	292	Missense	distal	-5	no	61.680	63.435	EPSD	TCGA;ICGC	56.683	Up-regulation
CAMK_CAMKL_AMPK_PRKAA1_ST	P43405	SYK	Q13131	PRKAA1	S307	G311R	311	Missense	distal	4	no	57.039	59.240	EPSD	TCGA;COSMIC	56.683	Up-regulation
CAMK_CAMKL_AMPK_PRKAA1_ST	P43405	SYK	Q13131	PRKAA1	S316	G311R	311	Missense	distal	-5	no	59.006	62.014	EPSD	TCGA;COSMIC	56.683	Up-regulation
CAMK_CAMKL_AMPK_PRKAA1_ST	P43405	SYK	Q13131	PRKAA1	S316	S316G	316	Missense	central	0	yes	59.006	0.000	EPSD	TCGA;COSMIC	56.683	Loss
CAMK_CAMKL_AMPK_PRKAA1_ST	P43405	SYK	Q13131	PRKAA1	S316	F320L	320	Missense	distal	4	no	59.006	63.200	EPSD	TCGA;COSMIC	56.683	Up-regulation
CAMK_CAMKL_AMPK_PRKAA1_ST	P43405	SYK	Q13131	PRKAA1	S579	G575E	575	Missense	distal	-4	no	54.610	58.163	EPSD	TCGA;COSMIC	56.683	Gain
CAMK_CAMKL_AMPK_PRKAA1_ST	O00763	ACACB	Q13131	PRKAA1	S37	A39T	39	Missense	proximal	2	no	68.031	68.478	EPSD	TCGA;ICGC;COSMIC	56.683	Up-regulation
CAMK_CAMKL_AMPK_PRKAA1_ST	O00763	ACACB	Q13131	PRKAA1	S37	E38K	38	Missense	proximal	1	no	68.031	68.961	EPSD	TCGA;ICGC;COSMIC	56.683	Up-regulation
CAMK_CAMKL_AMPK_PRKAA1_ST	O00763	ACACB	Q13131	PRKAA1	S37	K34N	34	Missense	distal	-3	no	68.031	66.736	EPSD	TCGA;ICGC;COSMIC	56.683	Down-regulation
CAMK_CAMKL_AMPK_PRKAA1_ST	O00763	ACACB	Q13131	PRKAA1	S192	R185C	185	Missense	distal	-7	no	59.804	58.411	EPSD	TCGA;ICGC;COSMIC;CCLE	56.683	Down-regulation
CAMK_CAMKL_AMPK_PRKAA1_ST	O00763	ACACB	Q13131	PRKAA1	S192	A198V	198	Missense	distal	6	no	59.804	59.599	EPSD	TCGA;ICGC	56.683	Down-regulation
CAMK_CAMKL_AMPK_PRKAA1_ST	O00763	ACACB	Q13131	PRKAA1	T216	R213C	213	Missense	distal	-3	no	60.087	45.940	EPSD	TCGA;ICGC;COSMIC	56.683	Loss
CAMK_CAMKL_AMPK_PRKAA1_ST	O00763	ACACB	Q13131	PRKAA1	T216	V214I	214	Missense	proximal	-2	no	60.087	58.202	EPSD	TCGA;ICGC;COSMIC;GDSC;CCLE	56.683	Down-regulation
CAMK_CAMKL_AMPK_PRKAA1_ST	O00763	ACACB	Q13131	PRKAA1	S222	R218M	218	Missense	distal	-4	no	62.768	60.236	PhosphoSitePlus	TCGA;ICGC	56.683	Down-regulation
CAMK_CAMKL_AMPK_PRKAA1_ST	O00763	ACACB	Q13131	PRKAA1	T243	E249K	249	Missense	distal	6	no	58.555	58.327	EPSD	TCGA;ICGC;COSMIC	56.683	Down-regulation
CAMK_CAMKL_AMPK_PRKAA1_ST	O00763	ACACB	Q13131	PRKAA1	T243	D241Y	241	Missense	proximal	-2	no	58.555	58.705	EPSD	TCGA;ICGC;COSMIC	56.683	Up-regulation
CAMK_CAMKL_AMPK_PRKAA1_ST	O00763	ACACB	Q13131	PRKAA1	T243	T243N	243	Missense	central	0	yes	58.555	0.000	EPSD	TCGA;ICGC;COSMIC	56.683	Loss
CAMK_CAMKL_AMPK_PRKAA1_ST	O00763	ACACB	Q13131	PRKAA1	T243	H239N	239	Missense	distal	-4	no	58.555	56.078	EPSD	TCGA;ICGC;COSMIC	56.683	Loss
CAMK_CAMKL_AMPK_PRKAA1_ST	O00763	ACACB	Q13131	PRKAA1	T243	T243A	243	Missense	central	0	yes	58.555	0.000	EPSD	TCGA;ICGC;COSMIC	56.683	Loss
CAMK_CAMKL_AMPK_PRKAA1_ST	O00763	ACACB	Q13131	PRKAA1	S469	R465Q	465	Missense	distal	-4	no	65.316	63.848	EPSD	TCGA;ICGC;COSMIC;GDSC;CCLE	56.683	Down-regulation
CAMK_CAMKL_AMPK_PRKAA1_ST	O00763	ACACB	Q13131	PRKAA1	S469	E468V	468	Missense	proximal	-1	no	65.316	65.328	EPSD	TCGA;ICGC;COSMIC	56.683	Up-regulation
CAMK_CAMKL_AMPK_PRKAA1_ST	O00763	ACACB	Q13131	PRKAA1	S469	S469I	469	Missense	central	0	yes	65.316	0.000	EPSD	TCGA;ICGC;COSMIC	56.683	Loss
CAMK_CAMKL_AMPK_PRKAA1_ST	O00763	ACACB	Q13131	PRKAA1	S469	L476F	476	Missense	distal	7	no	65.316	64.006	EPSD	TCGA;ICGC;COSMIC	56.683	Down-regulation
CAMK_CAMKL_AMPK_PRKAA1_ST	O00763	ACACB	Q13131	PRKAA1	S469	K466N	466	Missense	distal	-3	no	65.316	64.021	EPSD	TCGA;ICGC	56.683	Down-regulation
CAMK_CAMKL_AMPK_PRKAA1_ST	O00763	ACACB	Q13131	PRKAA1	S1081	A1085T	1085	Missense	distal	4	no	57.172	54.604	EPSD	TCGA;ICGC;COSMIC	56.683	Loss
CAMK_CAMKL_AMPK_PRKAA1_ST	O00763	ACACB	Q13131	PRKAA1	S1557	F1558L	1558	Missense	proximal	1	no	67.527	62.061	EPSD	TCGA;COSMIC	56.683	Down-regulation
CAMK_CAMKL_AMPK_PRKAA1_ST	O00763	ACACB	Q13131	PRKAA1	S1557	E1559K	1559	Missense	proximal	2	no	67.527	67.134	EPSD	TCGA;COSMIC	56.683	Down-regulation
CAMK_CAMKL_AMPK_PRKAA1_ST	O00763	ACACB	Q13131	PRKAA1	S1620	R1621P	1621	Missense	proximal	1	no	63.001	63.356	EPSD	TCGA;COSMIC	56.683	Up-regulation
CAMK_CAMKL_AMPK_PRKAA1_ST	O00763	ACACB	Q13131	PRKAA1	S1877	L1875M	1875	Missense	proximal	-2	no	57.528	57.541	EPSD	TCGA;COSMIC	56.683	Up-regulation
CAMK_CAMKL_AMPK_PRKAA1_ST	Q13501	SQSTM1	Q13131	PRKAA1	S180	G173R	173	Missense	distal	-7	no	57.331	55.916	EPSD	TCGA;ICGC;COSMIC	56.683	Loss
CAMK_CAMKL_AMPK_PRKAA1_ST	Q13501	SQSTM1	Q13131	PRKAA1	S180	R183H	183	Missense	distal	3	no	57.331	53.763	EPSD	TCGA;ICGC	56.683	Loss
CAMK_CAMKL_AMPK_PRKAA1_ST	Q13501	SQSTM1	Q13131	PRKAA1	S180	L185F	185	Missense	distal	5	no	57.331	57.170	EPSD	TCGA	56.683	Down-regulation
CAMK_CAMKL_AMPK_PRKAA1_ST	Q13501	SQSTM1	Q13131	PRKAA1	S182	R183H	183	Missense	proximal	1	no	54.042	57.040	EPSD	TCGA;ICGC	56.683	Gain
CAMK_CAMKL_AMPK_PRKAA1_ST	Q13501	SQSTM1	Q13131	PRKAA1	S233	S229L	229	Missense	distal	-4	no	58.665	57.170	EPSD	TCGA;COSMIC	56.683	Down-regulation
CAMK_CAMKL_AMPK_PRKAA1_ST	Q13501	SQSTM1	Q13131	PRKAA1	S233	K238N	238	Missense	distal	5	no	58.665	58.652	EPSD	TCGA;ICGC;COSMIC	56.683	Down-regulation
CAMK_CAMKL_AMPK_PRKAA1_ST	Q13501	SQSTM1	Q13131	PRKAA1	S233	P228L	228	Missense	distal	-5	no	58.665	63.405	EPSD	TCGA;COSMIC	56.683	Up-regulation
CAMK_CAMKL_AMPK_PRKAA1_ST	Q13501	SQSTM1	Q13131	PRKAA1	T269	S266R	266	Missense	distal	-3	no	49.554	58.950	EPSD	TCGA;ICGC	56.683	Gain
CAMK_CAMKL_AMPK_PRKAA1_ST	Q13501	SQSTM1	Q13131	PRKAA1	S284	S284A	284	Missense	central	0	yes	63.501	0.000	EPSD	TCGA;ICGC;COSMIC	56.683	Loss
CAMK_CAMKL_AMPK_PRKAA1_ST	Q13501	SQSTM1	Q13131	PRKAA1	S284	S277G	277	Missense	distal	-7	no	63.501	63.920	EPSD	TCGA;ICGC;COSMIC	56.683	Up-regulation
CAMK_CAMKL_AMPK_PRKAA1_ST	Q13501	SQSTM1	Q13131	PRKAA1	S284	S277I	277	Missense	distal	-7	no	63.501	61.149	EPSD	TCGA;ICGC	56.683	Down-regulation
CAMK_CAMKL_AMPK_PRKAA1_ST	Q13501	SQSTM1	Q13131	PRKAA1	S294	P293S	293	Missense	proximal	-1	no	64.675	64.720	PhosphoSitePlus	TCGA;ICGC;COSMIC	56.683	Up-regulation
CAMK_CAMKL_AMPK_PRKAA1_ST	Q13501	SQSTM1	Q13131	PRKAA1	S349	P348L	348	Missense	proximal	-1	no	61.532	61.603	EPSD	TCGA;COSMIC	56.683	Up-regulation
CAMK_CAMKL_AMPK_PRKAA1_ST	Q13501	SQSTM1	Q13131	PRKAA1	S349	E345K	345	Missense	distal	-4	no	61.532	58.407	EPSD	TCGA;COSMIC	56.683	Down-regulation
CMGC_CDK_CRK7_CDK12_ST	P24928	POLR2A	Q9NYV4	CDK12	S27	F23L	23	Missense	distal	-4	no	3.928	3.793	EPSD	TCGA;ICGC;COSMIC	0.929	Down-regulation
CMGC_CDK_CRK7_CDK12_ST	P24928	POLR2A	Q9NYV4	CDK12	S217	L215R	215	Missense	proximal	-2	no	4.639	4.605	EPSD	TCGA;ICGC;COSMIC	0.929	Down-regulation
CMGC_CDK_CRK7_CDK12_ST	P24928	POLR2A	Q9NYV4	CDK12	S217	E223K	223	Missense	distal	6	no	4.639	4.629	EPSD	TCGA;ICGC;COSMIC	0.929	Down-regulation
CMGC_CDK_CRK7_CDK12_ST	P24928	POLR2A	Q9NYV4	CDK12	S217	L215P	215	Missense	proximal	-2	no	4.639	4.587	EPSD	TCGA;ICGC	0.929	Down-regulation
CMGC_CDK_CRK7_CDK12_ST	P24928	POLR2A	Q9NYV4	CDK12	S217	R220Q	220	Missense	distal	3	no	4.639	4.636	EPSD	TCGA;ICGC	0.929	Down-regulation
CMGC_CDK_CRK7_CDK12_ST	P24928	POLR2A	Q9NYV4	CDK12	T368	P369T	369	Missense	proximal	1	no	4.124	-0.061	EPSD	TCGA;ICGC;COSMIC	0.929	Loss
CMGC_CDK_CRK7_CDK12_ST	P24928	POLR2A	Q9NYV4	CDK12	S1508	M1510L	1510	Missense	proximal	2	no	4.104	4.049	EPSD	TCGA;ICGC	0.929	Down-regulation
CMGC_CDK_CRK7_CDK12_ST	P24928	POLR2A	Q9NYV4	CDK12	S1508	G1504V	1504	Missense	distal	-4	no	4.104	3.993	EPSD	TCGA;ICGC	0.929	Down-regulation
CMGC_CDK_CRK7_CDK12_ST	P24928	POLR2A	Q9NYV4	CDK12	S1508	F1502L	1502	Missense	distal	-6	no	4.104	4.097	EPSD	TCGA;ICGC	0.929	Down-regulation
CMGC_CDK_CRK7_CDK12_ST	P24928	POLR2A	Q9NYV4	CDK12	S1514	M1510L	1510	Missense	distal	-4	no	4.438	4.277	EPSD	TCGA;ICGC	0.929	Down-regulation
CMGC_CDK_CRK7_CDK12_ST	P24928	POLR2A	Q9NYV4	CDK12	S1514	A1516V	1516	Missense	proximal	2	no	4.438	4.394	EPSD	TCGA;ICGC	0.929	Down-regulation
CMGC_CDK_CRK7_CDK12_ST	P24928	POLR2A	Q9NYV4	CDK12	S1514	M1517V	1517	Missense	distal	3	no	4.438	4.433	EPSD	TCGA;ICGC	0.929	Down-regulation
CMGC_CDK_CRK7_CDK12_ST	P24928	POLR2A	Q9NYV4	CDK12	T1518	A1516V	1516	Missense	proximal	-2	no	4.257	4.274	EPSD	TCGA;ICGC	0.929	Up-regulation
CMGC_CDK_CRK7_CDK12_ST	P24928	POLR2A	Q9NYV4	CDK12	T1518	M1517V	1517	Missense	proximal	-1	no	4.257	4.260	EPSD	TCGA;ICGC	0.929	Up-regulation
CMGC_CDK_CRK7_CDK12_ST	P24928	POLR2A	Q9NYV4	CDK12	S1532	A1527V	1527	Missense	distal	-5	no	4.196	4.178	EPSD	TCGA;ICGC	0.929	Down-regulation
CMGC_CDK_CRK7_CDK12_ST	P24928	POLR2A	Q9NYV4	CDK12	T1568	P1572L	1572	Missense	distal	4	no	5.189	4.448	EPSD	TCGA;ICGC	0.929	Down-regulation
CMGC_CDK_CRK7_CDK12_ST	P24928	POLR2A	Q9NYV4	CDK12	T1568	G1570S	1570	Missense	proximal	2	no	5.189	5.240	EPSD	TCGA;ICGC	0.929	Up-regulation
CMGC_CDK_CRK7_CDK12_ST	P24928	POLR2A	Q9NYV4	CDK12	S1571	P1572L	1572	Missense	proximal	1	no	5.658	0.778	EPSD	TCGA;ICGC	0.929	Loss
CMGC_CDK_CRK7_CDK12_ST	P24928	POLR2A	Q9NYV4	CDK12	S1571	G1570S	1570	Missense	proximal	-1	no	5.658	5.643	EPSD	TCGA;ICGC	0.929	Down-regulation
CMGC_CDK_CRK7_CDK12_ST	P24928	POLR2A	Q9NYV4	CDK12	S1574	P1572L	1572	Missense	proximal	-2	no	4.953	5.005	EPSD	TCGA;ICGC	0.929	Up-regulation
CMGC_CDK_CRK7_CDK12_ST	P24928	POLR2A	Q9NYV4	CDK12	S1574	G1570S	1570	Missense	distal	-4	no	4.953	5.041	EPSD	TCGA;ICGC	0.929	Up-regulation
CMGC_CDK_CRK7_CDK12_ST	P24928	POLR2A	Q9NYV4	CDK12	S1590	P1591L	1591	Missense	proximal	1	no	4.100	-0.780	EPSD	TCGA;ICGC	0.929	Loss
CMGC_CDK_CRK7_CDK12_ST	P24928	POLR2A	Q9NYV4	CDK12	S1594	P1591L	1591	Missense	distal	-3	no	4.883	4.935	EPSD	TCGA;ICGC	0.929	Up-regulation
CMGC_CDK_CRK7_CDK12_ST	P24928	POLR2A	Q9NYV4	CDK12	S1597	R1603H	1603	Missense	distal	6	no	4.123	4.122	EPSD	TCGA;ICGC	0.929	Down-regulation
CMGC_CDK_CRK7_CDK12_ST	P24928	POLR2A	Q9NYV4	CDK12	S1597	P1591L	1591	Missense	distal	-6	no	4.123	4.088	EPSD	TCGA;ICGC	0.929	Down-regulation
CMGC_CDK_CRK7_CDK12_ST	P24928	POLR2A	Q9NYV4	CDK12	S1619	T1625A	1625	Missense	distal	6	no	3.907	3.906	EPSD;PhosphoSitePlus	TCGA;ICGC	0.929	Down-regulation
CMGC_CDK_CRK7_CDK12_ST	P24928	POLR2A	Q9NYV4	CDK12	S1621	T1625A	1625	Missense	distal	4	no	1.088	1.007	EPSD	TCGA;ICGC	0.929	Down-regulation
CMGC_CDK_CRK7_CDK12_ST	P24928	POLR2A	Q9NYV4	CDK12	S1626	T1625A	1625	Missense	proximal	-1	no	4.368	4.358	EPSD	TCGA;ICGC	0.929	Down-regulation
CMGC_CDK_CRK7_CDK12_ST	P24928	POLR2A	Q9NYV4	CDK12	S1626	S1630Y	1630	Missense	distal	4	no	4.368	4.238	EPSD	TCGA	0.929	Down-regulation
CMGC_CDK_CRK7_CDK12_ST	P24928	POLR2A	Q9NYV4	CDK12	S1626	P1631S	1631	Missense	distal	5	no	4.368	4.411	EPSD	TCGA;ICGC	0.929	Up-regulation
CMGC_CDK_CRK7_CDK12_ST	P24928	POLR2A	Q9NYV4	CDK12	S1626	P1631L	1631	Missense	distal	5	no	4.368	4.393	EPSD	TCGA;ICGC	0.929	Up-regulation
CMGC_CDK_CRK7_CDK12_ST	P24928	POLR2A	Q9NYV4	CDK12	S1675	S1677N	1677	Missense	proximal	2	no	4.368	4.354	EPSD	TCGA;ICGC	0.929	Down-regulation
CMGC_CDK_CRK7_CDK12_ST	P24928	POLR2A	Q9NYV4	CDK12	S1682	S1677N	1677	Missense	distal	-5	no	4.368	4.364	EPSD	TCGA;ICGC	0.929	Down-regulation
CMGC_CDK_CRK7_CDK12_ST	P24928	POLR2A	Q9NYV4	CDK12	S1689	T1695M	1695	Missense	distal	6	no	4.368	4.365	EPSD	TCGA;ICGC	0.929	Down-regulation
CMGC_CDK_CRK7_CDK12_ST	P24928	POLR2A	Q9NYV4	CDK12	S1696	T1702I	1702	Missense	distal	6	no	4.368	4.363	EPSD	TCGA;ICGC	0.929	Down-regulation
CMGC_CDK_CRK7_CDK12_ST	P24928	POLR2A	Q9NYV4	CDK12	S1696	T1702S	1702	Missense	distal	6	no	4.368	4.371	EPSD	TCGA;ICGC	0.929	Up-regulation
CMGC_CDK_CRK7_CDK12_ST	P24928	POLR2A	Q9NYV4	CDK12	S1696	T1695M	1695	Missense	proximal	-1	no	4.368	4.372	EPSD	TCGA;ICGC	0.929	Up-regulation
CMGC_CDK_CRK7_CDK12_ST	P24928	POLR2A	Q9NYV4	CDK12	S1696	S1700L	1700	Missense	distal	4	no	4.368	4.074	EPSD	TCGA;ICGC	0.929	Down-regulation
CMGC_CDK_CRK7_CDK12_ST	P24928	POLR2A	Q9NYV4	CDK12	S1703	T1702I	1702	Missense	proximal	-1	no	4.368	4.386	EPSD	TCGA;ICGC	0.929	Up-regulation
CMGC_CDK_CRK7_CDK12_ST	P24928	POLR2A	Q9NYV4	CDK12	S1703	T1702S	1702	Missense	proximal	-1	no	4.368	4.344	EPSD	TCGA;ICGC	0.929	Down-regulation
CMGC_CDK_CRK7_CDK12_ST	P24928	POLR2A	Q9NYV4	CDK12	S1703	S1700L	1700	Missense	distal	-3	no	4.368	4.326	EPSD	TCGA;ICGC	0.929	Down-regulation
CMGC_CDK_CRK7_CDK12_ST	P24928	POLR2A	Q9NYV4	CDK12	S1731	P1732L	1732	Missense	proximal	1	no	4.492	-0.388	EPSD	TCGA;ICGC;CCLE	0.929	Loss
CMGC_CDK_CRK7_CDK12_ST	P24928	POLR2A	Q9NYV4	CDK12	S1731	S1735A	1735	Missense	distal	4	no	4.492	4.352	EPSD	TCGA;ICGC	0.929	Down-regulation
CMGC_CDK_CRK7_CDK12_ST	P24928	POLR2A	Q9NYV4	CDK12	S1733	P1732L	1732	Missense	proximal	-1	no	0.837	0.943	EPSD	TCGA;ICGC;CCLE	0.929	Gain
CMGC_CDK_CRK7_CDK12_ST	P24928	POLR2A	Q9NYV4	CDK12	S1738	T1744I	1744	Missense	distal	6	no	4.184	4.178	EPSD	TCGA;ICGC	0.929	Down-regulation
CMGC_CDK_CRK7_CDK12_ST	P24928	POLR2A	Q9NYV4	CDK12	S1738	S1745N	1745	Missense	distal	7	no	4.184	4.193	EPSD	TCGA;ICGC	0.929	Up-regulation
CMGC_CDK_CRK7_CDK12_ST	P24928	POLR2A	Q9NYV4	CDK12	S1738	P1732L	1732	Missense	distal	-6	no	4.184	4.149	EPSD	TCGA;ICGC;CCLE	0.929	Down-regulation
CMGC_CDK_CRK7_CDK12_ST	P24928	POLR2A	Q9NYV4	CDK12	S1738	S1735A	1735	Missense	distal	-3	no	4.184	4.162	EPSD	TCGA;ICGC	0.929	Down-regulation
CMGC_CDK_CRK7_CDK12_ST	P24928	POLR2A	Q9NYV4	CDK12	S1766	P1764S	1764	Missense	proximal	-2	no	3.736	3.751	EPSD	TCGA;ICGC	0.929	Up-regulation
CMGC_CDK_CRK7_CDK12_ST	P24928	POLR2A	Q9NYV4	CDK12	S1766	T1772I	1772	Missense	distal	6	no	3.736	3.731	EPSD	TCGA;ICGC	0.929	Down-regulation
CMGC_CDK_CRK7_CDK12_ST	P24928	POLR2A	Q9NYV4	CDK12	S1794	S1787F	1787	Missense	distal	-7	no	4.615	4.524	EPSD	TCGA;ICGC	0.929	Down-regulation
CMGC_CDK_CRK7_CDK12_ST	P24928	POLR2A	Q9NYV4	CDK12	T1812	P1816A	1816	Missense	distal	4	no	4.700	4.113	EPSD	TCGA;ICGC	0.929	Down-regulation
CMGC_CDK_CRK7_CDK12_ST	P24928	POLR2A	Q9NYV4	CDK12	T1812	P1809S	1809	Missense	distal	-3	no	4.700	4.794	EPSD	TCGA;ICGC	0.929	Up-regulation
CMGC_CDK_CRK7_CDK12_ST	P24928	POLR2A	Q9NYV4	CDK12	S1815	P1816A	1816	Missense	proximal	1	no	4.484	0.235	EPSD	TCGA;ICGC	0.929	Loss
CMGC_CDK_CRK7_CDK12_ST	P24928	POLR2A	Q9NYV4	CDK12	S1815	Y1818C	1818	Missense	distal	3	no	4.484	4.485	EPSD	TCGA	0.929	Up-regulation
CMGC_CDK_CRK7_CDK12_ST	P24928	POLR2A	Q9NYV4	CDK12	S1815	P1809S	1809	Missense	distal	-6	no	4.484	4.462	EPSD	TCGA;ICGC	0.929	Down-regulation
CMGC_CDK_CRK7_CDK12_ST	P24928	POLR2A	Q9NYV4	CDK12	T1817	P1816A	1816	Missense	proximal	-1	no	1.322	1.381	EPSD	TCGA;ICGC	0.929	Up-regulation
CMGC_CDK_CRK7_CDK12_ST	P24928	POLR2A	Q9NYV4	CDK12	T1817	Y1818C	1818	Missense	proximal	1	no	1.322	1.550	EPSD	TCGA	0.929	Up-regulation
CMGC_CDK_CRK7_CDK12_ST	P24928	POLR2A	Q9NYV4	CDK12	T1819	P1816A	1816	Missense	distal	-3	no	4.702	4.775	EPSD	TCGA;ICGC	0.929	Up-regulation
CMGC_CDK_CRK7_CDK12_ST	P24928	POLR2A	Q9NYV4	CDK12	T1819	Y1818C	1818	Missense	proximal	-1	no	4.702	4.698	EPSD	TCGA	0.929	Down-regulation
CMGC_CDK_CRK7_CDK12_ST	P24928	POLR2A	Q9NYV4	CDK12	S1822	P1816A	1816	Missense	distal	-6	no	3.676	3.653	EPSD	TCGA;ICGC	0.929	Down-regulation
CMGC_CDK_CRK7_CDK12_ST	P24928	POLR2A	Q9NYV4	CDK12	S1822	Y1818C	1818	Missense	distal	-4	no	3.676	3.694	EPSD	TCGA	0.929	Up-regulation
CMGC_CDK_CRK7_CDK12_ST	P24928	POLR2A	Q9NYV4	CDK12	T1840	S1845P	1845	Missense	distal	5	no	4.803	4.760	EPSD	TCGA;GDSC;CCLE	0.929	Down-regulation
CMGC_CDK_CRK7_CDK12_ST	P24928	POLR2A	Q9NYV4	CDK12	T1840	S1845Y	1845	Missense	distal	5	no	4.803	4.784	EPSD	TCGA;ICGC	0.929	Down-regulation
CMGC_CDK_CRK7_CDK12_ST	P24928	POLR2A	Q9NYV4	CDK12	S1843	S1845P	1845	Missense	proximal	2	no	4.420	4.696	EPSD	TCGA;GDSC;CCLE	0.929	Up-regulation
CMGC_CDK_CRK7_CDK12_ST	P24928	POLR2A	Q9NYV4	CDK12	S1843	S1845Y	1845	Missense	proximal	2	no	4.420	4.369	EPSD	TCGA;ICGC	0.929	Down-regulation
CMGC_CDK_CRK7_CDK12_ST	P24928	POLR2A	Q9NYV4	CDK12	S1847	S1845P	1845	Missense	proximal	-2	no	4.644	4.629	EPSD	TCGA;GDSC;CCLE	0.929	Down-regulation
CMGC_CDK_CRK7_CDK12_ST	P24928	POLR2A	Q9NYV4	CDK12	S1847	S1845Y	1845	Missense	proximal	-2	no	4.644	4.663	EPSD	TCGA;ICGC	0.929	Up-regulation
CMGC_CDK_CRK7_CDK12_ST	P24928	POLR2A	Q9NYV4	CDK12	S1849	S1845P	1845	Missense	distal	-4	no	0.697	1.345	EPSD	TCGA;GDSC;CCLE	0.929	Gain
CMGC_CDK_CRK7_CDK12_ST	P24928	POLR2A	Q9NYV4	CDK12	S1850	S1845P	1845	Missense	distal	-5	no	3.936	4.030	EPSD	TCGA;GDSC;CCLE	0.929	Up-regulation
CMGC_CDK_CRK7_CDK12_ST	P24928	POLR2A	Q9NYV4	CDK12	S1850	S1857C	1857	Missense	distal	7	no	3.936	3.934	EPSD	TCGA;ICGC	0.929	Down-regulation
CMGC_CDK_CRK7_CDK12_ST	P24928	POLR2A	Q9NYV4	CDK12	S1850	S1845Y	1845	Missense	distal	-5	no	3.936	3.920	EPSD	TCGA;ICGC	0.929	Down-regulation
CMGC_CDK_CRK7_CDK12_ST	P24928	POLR2A	Q9NYV4	CDK12	S1850	S1857F	1857	Missense	distal	7	no	3.936	3.920	EPSD	TCGA	0.929	Down-regulation
CMGC_CDK_CRK7_CDK12_ST	P24928	POLR2A	Q9NYV4	CDK12	T1854	S1857C	1857	Missense	distal	3	no	4.352	4.340	EPSD	TCGA;ICGC	0.929	Down-regulation
CMGC_CDK_CRK7_CDK12_ST	P24928	POLR2A	Q9NYV4	CDK12	T1854	S1857F	1857	Missense	distal	3	no	4.352	4.340	EPSD	TCGA	0.929	Down-regulation
CMGC_CDK_CRK7_CDK12_ST	P24928	POLR2A	Q9NYV4	CDK12	S1857	S1857C	1857	Missense	central	0	yes	4.546	0.000	EPSD	TCGA;ICGC	0.929	Loss
CMGC_CDK_CRK7_CDK12_ST	P24928	POLR2A	Q9NYV4	CDK12	S1857	S1857F	1857	Missense	central	0	yes	4.546	0.000	EPSD	TCGA	0.929	Loss
CMGC_CDK_CRK7_CDK12_ST	P24928	POLR2A	Q9NYV4	CDK12	S1861	S1857C	1857	Missense	distal	-4	no	4.330	4.250	EPSD	TCGA;ICGC	0.929	Down-regulation
CMGC_CDK_CRK7_CDK12_ST	P24928	POLR2A	Q9NYV4	CDK12	S1861	S1857F	1857	Missense	distal	-4	no	4.330	4.223	EPSD	TCGA	0.929	Down-regulation
CMGC_CDK_CRK7_CDK12_ST	P24928	POLR2A	Q9NYV4	CDK12	S1864	S1857C	1857	Missense	distal	-7	no	3.958	3.875	EPSD	TCGA;ICGC	0.929	Down-regulation
CMGC_CDK_CRK7_CDK12_ST	P24928	POLR2A	Q9NYV4	CDK12	S1864	S1857F	1857	Missense	distal	-7	no	3.958	3.867	EPSD	TCGA	0.929	Down-regulation
CMGC_CDK_CRK7_CDK12_ST	P24928	POLR2A	Q9NYV4	CDK12	S1868	S1875L	1875	Missense	distal	7	no	4.193	4.147	EPSD	TCGA;ICGC	0.929	Down-regulation
CMGC_CDK_CRK7_CDK12_ST	P24928	POLR2A	Q9NYV4	CDK12	S1871	Y1874H	1874	Missense	distal	3	no	4.249	4.252	EPSD	TCGA;ICGC	0.929	Up-regulation
CMGC_CDK_CRK7_CDK12_ST	P24928	POLR2A	Q9NYV4	CDK12	S1871	S1875L	1875	Missense	distal	4	no	4.249	3.954	EPSD	TCGA;ICGC	0.929	Down-regulation
CMGC_CDK_CRK7_CDK12_ST	P24928	POLR2A	Q9NYV4	CDK12	S1875	Y1874H	1874	Missense	proximal	-1	no	4.282	4.279	EPSD	TCGA;ICGC	0.929	Down-regulation
CMGC_CDK_CRK7_CDK12_ST	P24928	POLR2A	Q9NYV4	CDK12	S1875	S1875L	1875	Missense	central	0	yes	4.282	0.000	EPSD	TCGA;ICGC	0.929	Loss
CMGC_CDK_CRK7_CDK12_ST	P24928	POLR2A	Q9NYV4	CDK12	S1878	Y1874H	1874	Missense	distal	-4	no	4.605	4.629	EPSD	TCGA;ICGC	0.929	Up-regulation
CMGC_CDK_CRK7_CDK12_ST	P24928	POLR2A	Q9NYV4	CDK12	S1878	S1875L	1875	Missense	distal	-3	no	4.605	4.563	EPSD	TCGA;ICGC	0.929	Down-regulation
CMGC_CDK_CRK7_CDK12_ST	P24928	POLR2A	Q9NYV4	CDK12	S1882	S1875L	1875	Missense	distal	-7	no	4.391	4.277	EPSD	TCGA;ICGC	0.929	Down-regulation
CMGC_CDK_CRK7_CDK12_ST	P24928	POLR2A	Q9NYV4	CDK12	S1882	K1887N	1887	Missense	distal	5	no	4.391	4.372	EPSD	TCGA;ICGC	0.929	Down-regulation
CMGC_CDK_CRK7_CDK12_ST	P24928	POLR2A	Q9NYV4	CDK12	T1885	K1887N	1887	Missense	proximal	2	no	4.067	4.057	EPSD	TCGA;ICGC	0.929	Down-regulation
CMGC_CDK_CRK7_CDK12_ST	P24928	POLR2A	Q9NYV4	CDK12	S1889	S1896F	1896	Missense	distal	7	no	4.401	4.384	EPSD	TCGA;ICGC	0.929	Down-regulation
CMGC_CDK_CRK7_CDK12_ST	P24928	POLR2A	Q9NYV4	CDK12	S1889	K1887N	1887	Missense	proximal	-2	no	4.401	4.425	EPSD	TCGA;ICGC	0.929	Up-regulation
CMGC_CDK_CRK7_CDK12_ST	P24928	POLR2A	Q9NYV4	CDK12	S1892	T1898A	1898	Missense	distal	6	no	4.097	4.096	EPSD	TCGA;ICGC	0.929	Down-regulation
CMGC_CDK_CRK7_CDK12_ST	P24928	POLR2A	Q9NYV4	CDK12	S1892	S1896F	1896	Missense	distal	4	no	4.097	3.935	EPSD	TCGA;ICGC	0.929	Down-regulation
CMGC_CDK_CRK7_CDK12_ST	P24928	POLR2A	Q9NYV4	CDK12	S1892	K1887N	1887	Missense	distal	-5	no	4.097	4.101	EPSD	TCGA;ICGC	0.929	Up-regulation
CMGC_CDK_CRK7_CDK12_ST	P24928	POLR2A	Q9NYV4	CDK12	S1896	T1898A	1898	Missense	proximal	2	no	4.174	4.194	EPSD	TCGA;ICGC	0.929	Up-regulation
CMGC_CDK_CRK7_CDK12_ST	P24928	POLR2A	Q9NYV4	CDK12	S1896	S1896F	1896	Missense	central	0	yes	4.174	0.000	EPSD	TCGA;ICGC	0.929	Loss
CMGC_CDK_CRK7_CDK12_ST	P24928	POLR2A	Q9NYV4	CDK12	S1899	T1898A	1898	Missense	proximal	-1	no	4.022	4.012	EPSD	TCGA;ICGC	0.929	Down-regulation
CMGC_CDK_CRK7_CDK12_ST	P24928	POLR2A	Q9NYV4	CDK12	S1899	S1896F	1896	Missense	distal	-3	no	4.022	3.980	EPSD	TCGA;ICGC	0.929	Down-regulation
CMGC_CDK_CRK7_CDK12_ST	P24928	POLR2A	Q9NYV4	CDK12	T1903	T1898A	1898	Missense	distal	-5	no	4.623	4.634	EPSD	TCGA;ICGC	0.929	Up-regulation
CMGC_CDK_CRK7_CDK12_ST	P24928	POLR2A	Q9NYV4	CDK12	T1903	P1907S	1907	Missense	distal	4	no	4.623	4.176	EPSD	TCGA;ICGC	0.929	Down-regulation
CMGC_CDK_CRK7_CDK12_ST	P24928	POLR2A	Q9NYV4	CDK12	T1903	S1896F	1896	Missense	distal	-7	no	4.623	4.533	EPSD	TCGA;ICGC	0.929	Down-regulation
CMGC_CDK_CRK7_CDK12_ST	P24928	POLR2A	Q9NYV4	CDK12	S1906	P1907S	1907	Missense	proximal	1	no	4.088	-0.181	EPSD	TCGA;ICGC	0.929	Loss
CMGC_CDK_CRK7_CDK12_ST	P24928	POLR2A	Q9NYV4	CDK12	S1910	P1907S	1907	Missense	distal	-3	no	3.890	3.984	EPSD	TCGA;ICGC	0.929	Up-regulation
CMGC_CDK_CRK7_CDK12_ST	P24928	POLR2A	Q9NYV4	CDK12	S1913	P1907S	1907	Missense	distal	-6	no	3.778	3.756	EPSD	TCGA;ICGC	0.929	Down-regulation
CMGC_CDK_CRK7_CDK12_ST	P24928	POLR2A	Q9NYV4	CDK12	S1924	S1931L	1931	Missense	distal	7	no	4.485	4.439	EPSD	TCGA;ICGC	0.929	Down-regulation
CMGC_CDK_CRK7_CDK12_ST	P24928	POLR2A	Q9NYV4	CDK12	S1927	S1931L	1931	Missense	distal	4	no	4.242	3.947	EPSD	TCGA;ICGC	0.929	Down-regulation
CMGC_CDK_CRK7_CDK12_ST	P24928	POLR2A	Q9NYV4	CDK12	S1931	S1931L	1931	Missense	central	0	yes	4.437	0.000	EPSD	TCGA;ICGC	0.929	Loss
CMGC_CDK_CRK7_CDK12_ST	P24928	POLR2A	Q9NYV4	CDK12	S1934	S1931L	1931	Missense	distal	-3	no	4.022	3.980	EPSD	TCGA;ICGC	0.929	Down-regulation
CMGC_CDK_CRK7_CDK12_ST	P24928	POLR2A	Q9NYV4	CDK12	S1941	S1944F	1944	Missense	distal	3	no	4.371	4.359	EPSD	TCGA;ICGC	0.929	Down-regulation
CMGC_CDK_CRK7_CDK12_ST	P24928	POLR2A	Q9NYV4	CDK12	S1944	S1944F	1944	Missense	central	0	yes	4.099	0.000	EPSD	TCGA;ICGC	0.929	Loss
CMGC_CDK_CRK7_CDK12_ST	P24928	POLR2A	Q9NYV4	CDK12	S1948	S1944F	1944	Missense	distal	-4	no	5.150	5.043	EPSD	TCGA;ICGC	0.929	Down-regulation
CMGC_CDK_CRK7_CDK12_ST	P24928	POLR2A	Q9NYV4	CDK12	S1951	S1944F	1944	Missense	distal	-7	no	4.615	4.525	EPSD	TCGA;ICGC	0.929	Down-regulation
CMGC_CDK_CRK7_CDK12_ST	P24928	POLR2A	Q9NYV4	CDK12	S1958	I1961M	1961	Missense	distal	3	no	4.711	4.715	EPSD	TCGA;ICGC	0.929	Up-regulation
CMGC_CDK_CRK7_CDK12_ST	P24928	POLR2A	Q9NYV4	CDK12	S1962	I1961M	1961	Missense	proximal	-1	no	4.400	4.386	EPSD	TCGA;ICGC	0.929	Down-regulation
CAMK_CAMK1_CAMK4_ST	P16220	CREB1	Q16566	CAMK4	S98	S103A	103	Missense	distal	5	no	14.403	14.443	EPSD	TCGA;COSMIC	9.847	Up-regulation
CAMK_CAMK1_CAMK4_ST	P16220	CREB1	Q16566	CAMK4	S114	D116G	116	Missense	proximal	2	no	10.753	10.777	EPSD	TCGA;COSMIC	9.847	Up-regulation
CAMK_CAMK1_CAMK4_ST	P16220	CREB1	Q16566	CAMK4	S114	Q112H	112	Missense	proximal	-2	no	10.753	9.792	EPSD	TCGA;COSMIC	9.847	Loss
CAMK_CAMK1_CAMK4_ST	P16220	CREB1	Q16566	CAMK4	S133	L128I	128	Missense	distal	-5	no	14.892	13.743	PhosphoSitePlus	TCGA;COSMIC	9.847	Down-regulation
CAMK_CAMK1_CAMK4_ST	P14866	HNRNPL	Q16566	CAMK4	S180	S174C	174	Missense	distal	-6	no	10.888	10.791	EPSD	TCGA;COSMIC	9.847	Down-regulation
CAMK_CAMK1_CAMK4_ST	P14866	HNRNPL	Q16566	CAMK4	S180	I179V	179	Missense	proximal	-1	no	10.888	11.190	EPSD	TCGA;COSMIC	9.847	Up-regulation
CAMK_CAMK1_CAMK4_ST	P14866	HNRNPL	Q16566	CAMK4	S180	S180F	180	Missense	central	0	yes	10.888	0.000	EPSD	TCGA;COSMIC	9.847	Loss
CAMK_CAMK1_CAMK4_ST	P14866	HNRNPL	Q16566	CAMK4	S180	S174F	174	Missense	distal	-6	no	10.888	10.707	EPSD	TCGA;COSMIC	9.847	Down-regulation
CAMK_CAMK1_CAMK4_ST	P14866	HNRNPL	Q16566	CAMK4	S188	V191M	191	Missense	distal	3	no	10.614	10.792	EPSD	TCGA;COSMIC	9.847	Up-regulation
CAMK_CAMK1_CAMK4_ST	P14866	HNRNPL	Q16566	CAMK4	S250	A247P	247	Missense	distal	-3	no	10.645	10.049	EPSD	TCGA;COSMIC	9.847	Down-regulation
CAMK_CAMK1_CAMK4_ST	P14866	HNRNPL	Q16566	CAMK4	S250	Y257C	257	Missense	distal	7	no	10.645	11.168	EPSD	TCGA;COSMIC	9.847	Up-regulation
CAMK_CAMK1_CAMK4_ST	P14866	HNRNPL	Q16566	CAMK4	T487	R481Q	481	Missense	distal	-6	no	12.576	12.457	EPSD	TCGA;COSMIC	9.847	Down-regulation
CAMK_CAMK1_CAMK4_ST	P14866	HNRNPL	Q16566	CAMK4	T487	R481W	481	Missense	distal	-6	no	12.576	12.381	EPSD	TCGA;COSMIC	9.847	Down-regulation
CAMK_CAMK1_CAMK4_ST	Q99623	PHB2	Q16566	CAMK4	S91	G95C	95	Missense	distal	4	no	15.761	15.742	PhosphoSitePlus	TCGA;ICGC;COSMIC	9.847	Down-regulation
CAMK_CAMK1_CAMK4_ST	Q99623	PHB2	Q16566	CAMK4	S92	G95C	95	Missense	distal	3	no	12.195	12.090	EPSD	TCGA;ICGC;COSMIC	9.847	Down-regulation
CAMK_CAMK1_CAMK4_ST	Q99623	PHB2	Q16566	CAMK4	S96	G95C	95	Missense	proximal	-1	no	10.857	10.456	EPSD	TCGA;ICGC;COSMIC	9.847	Down-regulation
CAMK_CAMK1_CAMK4_ST	Q99623	PHB2	Q16566	CAMK4	S96	N103S	103	Missense	distal	7	no	10.857	12.665	EPSD	TCGA;ICGC;COSMIC	9.847	Up-regulation
CAMK_CAMK1_CAMK4_ST	Q99623	PHB2	Q16566	CAMK4	S151	N149S	149	Missense	proximal	-2	no	9.464	10.221	EPSD	TCGA;ICGC;COSMIC	9.847	Gain
CAMK_CAMK1_CAMK4_ST	Q99623	PHB2	Q16566	CAMK4	T194	A195D	195	Missense	proximal	1	no	10.549	10.259	EPSD	TCGA;ICGC	9.847	Down-regulation
CAMK_CAMK1_CAMK4_ST	Q9UQM7	CAMK2A	Q16566	CAMK4	T286	V287M	287	Missense	proximal	1	no	10.649	10.719	EPSD	TCGA;ICGC;COSMIC	9.847	Up-regulation
CAMK_CAMK1_CAMK4_ST	Q9UQM7	CAMK2A	Q16566	CAMK4	S314	F313L	313	Missense	proximal	-1	no	12.919	13.263	EPSD	TCGA;ICGC;COSMIC	9.847	Up-regulation
CAMK_CAMK1_CAMK4_ST	Q04206	RELA	Q16566	CAMK4	S42	E39K	39	Missense	distal	-3	no	6.020	10.732	EPSD	TCGA;ICGC;COSMIC	9.847	Gain
CAMK_CAMK1_CAMK4_ST	Q04206	RELA	Q16566	CAMK4	S45	E39K	39	Missense	distal	-6	no	10.149	10.345	EPSD	TCGA;ICGC;COSMIC	9.847	Up-regulation
CAMK_CAMK1_CAMK4_ST	Q04206	RELA	Q16566	CAMK4	S45	E49K	49	Missense	distal	4	no	10.149	10.193	EPSD	TCGA;ICGC;COSMIC	9.847	Up-regulation
CAMK_CAMK1_CAMK4_ST	Q04206	RELA	Q16566	CAMK4	S45	G44V	44	Missense	proximal	-1	no	10.149	10.090	EPSD	TCGA;ICGC;COSMIC	9.847	Down-regulation
CAMK_CAMK1_CAMK4_ST	Q04206	RELA	Q16566	CAMK4	S131	R133H	133	Missense	proximal	2	no	10.188	10.239	EPSD	TCGA;ICGC;COSMIC	9.847	Up-regulation
CAMK_CAMK1_CAMK4_ST	Q04206	RELA	Q16566	CAMK4	S131	E127K	127	Missense	distal	-4	no	10.188	10.618	EPSD	TCGA;ICGC;COSMIC	9.847	Up-regulation
CAMK_CAMK1_CAMK4_ST	Q04206	RELA	Q16566	CAMK4	S269	S276F	276	Missense	distal	7	no	10.555	7.831	EPSD	TCGA;ICGC;COSMIC	9.847	Loss
CAMK_CAMK1_CAMK4_ST	Q04206	RELA	Q16566	CAMK4	S269	R274W	274	Missense	distal	5	no	10.555	10.216	EPSD	TCGA;ICGC	9.847	Down-regulation
CAMK_CAMK1_CAMK4_ST	Q04206	RELA	Q16566	CAMK4	S269	R273W	273	Missense	distal	4	no	10.555	10.293	EPSD	TCGA;ICGC	9.847	Down-regulation
CAMK_CAMK1_CAMK4_ST	Q04206	RELA	Q16566	CAMK4	S276	S276F	276	Missense	central	0	yes	14.867	0.000	EPSD	TCGA;ICGC;COSMIC	9.847	Loss
CAMK_CAMK1_CAMK4_ST	Q04206	RELA	Q16566	CAMK4	S276	R274W	274	Missense	proximal	-2	no	14.867	12.890	EPSD	TCGA;ICGC	9.847	Down-regulation
CAMK_CAMK1_CAMK4_ST	Q04206	RELA	Q16566	CAMK4	S276	R273W	273	Missense	distal	-3	no	14.867	8.215	EPSD	TCGA;ICGC	9.847	Loss
CAMK_CAMK1_CAMK4_ST	Q04206	RELA	Q16566	CAMK4	S281	S276F	276	Missense	distal	-5	no	12.264	11.470	EPSD	TCGA;ICGC;COSMIC	9.847	Down-regulation
CAMK_CAMK1_CAMK4_ST	Q04206	RELA	Q16566	CAMK4	S281	R274W	274	Missense	distal	-7	no	12.264	10.231	EPSD	TCGA;ICGC	9.847	Down-regulation
CAMK_CAMK1_CAMK4_ST	Q04206	RELA	Q16566	CAMK4	T305	F309L	309	Missense	distal	4	no	10.192	10.734	EPSD	TCGA;ICGC;COSMIC	9.847	Up-regulation
CAMK_CAMK1_CAMK4_ST	Q04206	RELA	Q16566	CAMK4	T305	E307K	307	Missense	proximal	2	no	10.192	10.171	EPSD	TCGA;ICGC;COSMIC	9.847	Down-regulation
CAMK_CAMK1_CAMK4_ST	Q04206	RELA	Q16566	CAMK4	T305	T308A	308	Missense	distal	3	no	10.192	10.372	EPSD	TCGA;ICGC;COSMIC	9.847	Up-regulation
CAMK_CAMK1_CAMK4_ST	Q04206	RELA	Q16566	CAMK4	S337	A339T	339	Missense	proximal	2	no	11.395	11.426	EPSD	TCGA;ICGC;COSMIC;CCLE	9.847	Up-regulation
CAMK_CAMK1_CAMK4_ST	Q04206	RELA	Q16566	CAMK4	S337	A332D	332	Missense	distal	-5	no	11.395	11.104	EPSD	TCGA;ICGC	9.847	Down-regulation
CAMK_CAMK1_CAMK4_ST	Q04206	RELA	Q16566	CAMK4	S338	A339T	339	Missense	proximal	1	no	12.082	11.908	EPSD	TCGA;ICGC;COSMIC;CCLE	9.847	Down-regulation
CAMK_CAMK1_CAMK4_ST	Q04206	RELA	Q16566	CAMK4	S338	A332D	332	Missense	distal	-6	no	12.082	11.965	EPSD	TCGA;ICGC	9.847	Down-regulation
CAMK_CAMK1_CAMK4_ST	Q04206	RELA	Q16566	CAMK4	S340	A339T	339	Missense	proximal	-1	no	11.357	10.494	EPSD	TCGA;ICGC;COSMIC;CCLE	9.847	Down-regulation
CAMK_CAMK1_CAMK4_ST	Q04206	RELA	Q16566	CAMK4	S536	S529L	529	Missense	distal	-7	no	12.028	10.715	PhosphoSitePlus	TCGA;ICGC;COSMIC;GDSC;CCLE	9.847	Down-regulation
CAMK_CAMK1_CAMK4_ST	P16949	STMN1	Q16566	CAMK4	S63	E58D	58	Missense	distal	-5	no	14.468	14.574	EPSD	TCGA;ICGC;COSMIC	9.847	Up-regulation
CAMK_CAMK1_CAMK4_ST	P16949	STMN1	Q16566	CAMK4	S63	A66G	66	Missense	distal	3	no	14.468	14.193	EPSD	TCGA;ICGC;COSMIC	9.847	Down-regulation
CAMK_CAMK1_CAMK4_ST	P16949	STMN1	Q16566	CAMK4	S63	R61H	61	Missense	proximal	-2	no	14.468	12.153	EPSD	TCGA;ICGC;COSMIC	9.847	Down-regulation
CAMK_CAMK1_CAMK4_ST	P16949	STMN1	Q16566	CAMK4	S63	S63P	63	Missense	central	0	yes	14.468	0.000	EPSD	TCGA;ICGC;COSMIC	9.847	Loss
CAMK_CAMKL_AMPK_PRKAA2_ST	Q13393	PLD1	P54646	PRKAA2	S303	I307T	307	Missense	distal	4	no	45.236	47.723	EPSD	TCGA;ICGC;COSMIC	46.832	Gain
CAMK_CAMKL_AMPK_PRKAA2_ST	Q13393	PLD1	P54646	PRKAA2	S505	G498S	498	Missense	distal	-7	no	70.246	70.601	PhosphoSitePlus	TCGA;ICGC;COSMIC	46.832	Up-regulation
CAMK_CAMKL_AMPK_PRKAA2_ST	Q13393	PLD1	P54646	PRKAA2	S505	S508F	508	Missense	distal	3	no	70.246	66.083	PhosphoSitePlus	TCGA;ICGC;COSMIC	46.832	Down-regulation
CAMK_CAMKL_AMPK_PRKAA2_ST	Q13393	PLD1	P54646	PRKAA2	S505	K501T	501	Missense	distal	-4	no	70.246	69.646	PhosphoSitePlus	TCGA;ICGC;COSMIC	46.832	Down-regulation
CAMK_CAMKL_AMPK_PRKAA2_ST	Q13393	PLD1	P54646	PRKAA2	S511	S508F	508	Missense	distal	-3	no	53.367	48.685	EPSD	TCGA;ICGC;COSMIC	46.832	Down-regulation
CAMK_CAMKL_AMPK_PRKAA2_ST	Q13393	PLD1	P54646	PRKAA2	S511	A516T	516	Missense	distal	5	no	53.367	53.089	EPSD	TCGA;ICGC;COSMIC	46.832	Down-regulation
CAMK_CAMKL_AMPK_PRKAA2_ST	Q13393	PLD1	P54646	PRKAA2	S519	E521K	521	Missense	proximal	2	no	49.678	40.935	EPSD	TCGA;ICGC;COSMIC	46.832	Loss
CAMK_CAMKL_AMPK_PRKAA2_ST	Q13393	PLD1	P54646	PRKAA2	S519	S519Y	519	Missense	central	0	yes	49.678	0.000	EPSD	TCGA;ICGC;COSMIC	46.832	Loss
CAMK_CAMKL_AMPK_PRKAA2_ST	Q13393	PLD1	P54646	PRKAA2	S519	A516T	516	Missense	distal	-3	no	49.678	52.623	EPSD	TCGA;ICGC;COSMIC	46.832	Up-regulation
CAMK_CAMKL_AMPK_PRKAA2_ST	Q13393	PLD1	P54646	PRKAA2	S540	D545H	545	Missense	distal	5	no	47.072	46.820	EPSD	TCGA;ICGC;COSMIC	46.832	Loss
CAMK_CAMKL_AMPK_PRKAA2_ST	Q13393	PLD1	P54646	PRKAA2	S540	N534S	534	Missense	distal	-6	no	47.072	47.455	EPSD	TCGA;ICGC;COSMIC	46.832	Up-regulation
CAMK_CAMKL_AMPK_PRKAA2_ST	Q9UQL6	HDAC5	P54646	PRKAA2	S55	G52E	52	Missense	distal	-3	no	60.257	58.368	EPSD	TCGA;ICGC;COSMIC	46.832	Down-regulation
CAMK_CAMKL_AMPK_PRKAA2_ST	P09874	PARP1	P54646	PRKAA2	S25	E26Q	26	Missense	proximal	1	no	47.150	47.104	EPSD	TCGA;ICGC;COSMIC;CCLE	46.832	Down-regulation
CAMK_CAMKL_AMPK_PRKAA2_ST	P09874	PARP1	P54646	PRKAA2	S177	P174T	174	Missense	distal	-3	no	72.801	71.822	PhosphoSitePlus	TCGA;ICGC;COSMIC	46.832	Down-regulation
CAMK_CAMKL_AMPK_PRKAA2_ST	P09874	PARP1	P54646	PRKAA2	S177	A178V	178	Missense	proximal	1	no	72.801	72.660	PhosphoSitePlus	TCGA;ICGC;COSMIC;GDSC;CCLE	46.832	Down-regulation
CAMK_CAMKL_AMPK_PRKAA2_ST	P09874	PARP1	P54646	PRKAA2	T368	T368M	368	Missense	central	0	yes	47.400	0.000	EPSD	TCGA;GDSC;CCLE	46.832	Loss
CAMK_CAMKL_AMPK_PRKAA2_ST	P09874	PARP1	P54646	PRKAA2	T368	A363T	363	Missense	distal	-5	no	47.400	48.002	EPSD	TCGA;ICGC;COSMIC	46.832	Up-regulation
CAMK_CAMKL_AMPK_PRKAA2_ST	P09874	PARP1	P54646	PRKAA2	T368	P369L	369	Missense	proximal	1	no	47.400	47.517	EPSD	TCGA;ICGC;COSMIC	46.832	Up-regulation
CAMK_CAMKL_AMPK_PRKAA2_ST	P09874	PARP1	P54646	PRKAA2	T368	S375L	375	Missense	distal	7	no	47.400	47.820	EPSD	TCGA;ICGC;COSMIC	46.832	Up-regulation
CAMK_CAMKL_AMPK_PRKAA2_ST	P09874	PARP1	P54646	PRKAA2	T368	P371L	371	Missense	distal	3	no	47.400	49.056	EPSD	TCGA;ICGC;COSMIC	46.832	Up-regulation
CAMK_CAMKL_AMPK_PRKAA2_ST	P09874	PARP1	P54646	PRKAA2	T368	V365M	365	Missense	distal	-3	no	47.400	44.800	EPSD	TCGA;ICGC;COSMIC	46.832	Loss
CAMK_CAMKL_AMPK_PRKAA2_ST	P09874	PARP1	P54646	PRKAA2	S372	T368M	368	Missense	distal	-4	no	49.979	49.706	EPSD	TCGA;GDSC;CCLE	46.832	Down-regulation
CAMK_CAMKL_AMPK_PRKAA2_ST	P09874	PARP1	P54646	PRKAA2	S372	P369L	369	Missense	distal	-3	no	49.979	47.934	EPSD	TCGA;ICGC;COSMIC	46.832	Down-regulation
CAMK_CAMKL_AMPK_PRKAA2_ST	P09874	PARP1	P54646	PRKAA2	S372	S375L	375	Missense	distal	3	no	49.979	47.898	EPSD	TCGA;ICGC;COSMIC	46.832	Down-regulation
CAMK_CAMKL_AMPK_PRKAA2_ST	P09874	PARP1	P54646	PRKAA2	S372	P371L	371	Missense	proximal	-1	no	49.979	50.355	EPSD	TCGA;ICGC;COSMIC	46.832	Up-regulation
CAMK_CAMKL_AMPK_PRKAA2_ST	P09874	PARP1	P54646	PRKAA2	S372	V365M	365	Missense	distal	-7	no	49.979	50.013	EPSD	TCGA;ICGC;COSMIC	46.832	Up-regulation
CAMK_CAMKL_AMPK_PRKAA2_ST	P09874	PARP1	P54646	PRKAA2	T373	T368M	368	Missense	distal	-5	no	49.281	51.636	EPSD	TCGA;GDSC;CCLE	46.832	Up-regulation
CAMK_CAMKL_AMPK_PRKAA2_ST	P09874	PARP1	P54646	PRKAA2	T373	P369L	369	Missense	distal	-4	no	49.281	47.549	EPSD	TCGA;ICGC;COSMIC	46.832	Down-regulation
CAMK_CAMKL_AMPK_PRKAA2_ST	P09874	PARP1	P54646	PRKAA2	T373	S375L	375	Missense	proximal	2	no	49.281	45.339	EPSD	TCGA;ICGC;COSMIC	46.832	Loss
CAMK_CAMKL_AMPK_PRKAA2_ST	P09874	PARP1	P54646	PRKAA2	T373	P371L	371	Missense	proximal	-2	no	49.281	48.334	EPSD	TCGA;ICGC;COSMIC	46.832	Down-regulation
CAMK_CAMKL_AMPK_PRKAA2_ST	P09874	PARP1	P54646	PRKAA2	S375	T368M	368	Missense	distal	-7	no	48.725	48.525	EPSD	TCGA;GDSC;CCLE	46.832	Down-regulation
CAMK_CAMKL_AMPK_PRKAA2_ST	P09874	PARP1	P54646	PRKAA2	S375	P369L	369	Missense	distal	-6	no	48.725	48.129	EPSD	TCGA;ICGC;COSMIC	46.832	Down-regulation
CAMK_CAMKL_AMPK_PRKAA2_ST	P09874	PARP1	P54646	PRKAA2	S375	S375L	375	Missense	central	0	yes	48.725	0.000	EPSD	TCGA;ICGC;COSMIC	46.832	Loss
CAMK_CAMKL_AMPK_PRKAA2_ST	P09874	PARP1	P54646	PRKAA2	S375	P371L	371	Missense	distal	-4	no	48.725	46.993	EPSD	TCGA;ICGC;COSMIC	46.832	Down-regulation
CAMK_CAMKL_AMPK_PRKAA2_ST	P09874	PARP1	P54646	PRKAA2	S455	E456Q	456	Missense	proximal	1	no	53.514	53.468	EPSD	TCGA;ICGC;COSMIC	46.832	Down-regulation
CAMK_CAMKL_AMPK_PRKAA2_ST	P09874	PARP1	P54646	PRKAA2	S499	L503R	503	Missense	distal	4	no	58.269	41.783	EPSD	TCGA;ICGC;COSMIC	46.832	Loss
CAMK_CAMKL_AMPK_PRKAA2_ST	P09874	PARP1	P54646	PRKAA2	S499	A501T	501	Missense	proximal	2	no	58.269	54.562	EPSD	TCGA;ICGC;COSMIC	46.832	Down-regulation
CAMK_CAMKL_AMPK_PRKAA2_ST	P09874	PARP1	P54646	PRKAA2	S499	V492A	492	Missense	distal	-7	no	58.269	58.446	EPSD	TCGA;ICGC	46.832	Up-regulation
CAMK_CAMKL_AMPK_PRKAA2_ST	P09874	PARP1	P54646	PRKAA2	S537	H541R	541	Missense	distal	4	no	36.299	50.423	EPSD	TCGA;ICGC;COSMIC	46.832	Gain
CAMK_CAMKL_AMPK_PRKAA2_ST	O00418	EEF2K	P54646	PRKAA2	S66	S61G	61	Missense	distal	-5	no	46.464	47.352	EPSD	TCGA;ICGC	46.832	Gain
CAMK_CAMKL_AMPK_PRKAA2_ST	O00418	EEF2K	P54646	PRKAA2	S135	G141R	141	Missense	distal	6	no	46.303	47.046	EPSD	TCGA;ICGC;COSMIC	46.832	Gain
CAMK_CAMKL_AMPK_PRKAA2_ST	O00418	EEF2K	P54646	PRKAA2	T364	S366F	366	Missense	proximal	2	no	47.763	33.551	EPSD	TCGA;ICGC;COSMIC	46.832	Loss
CAMK_CAMKL_AMPK_PRKAA2_ST	O00418	EEF2K	P54646	PRKAA2	T364	S366C	366	Missense	proximal	2	no	47.763	49.672	EPSD	TCGA;ICGC;COSMIC	46.832	Up-regulation
CAMK_CAMKL_AMPK_PRKAA2_ST	O00418	EEF2K	P54646	PRKAA2	T364	P371S	371	Missense	distal	7	no	47.763	45.614	EPSD	TCGA;ICGC;COSMIC	46.832	Loss
CAMK_CAMKL_AMPK_PRKAA2_ST	O00418	EEF2K	P54646	PRKAA2	S377	P371S	371	Missense	distal	-6	no	55.566	56.929	EPSD	TCGA;ICGC;COSMIC	46.832	Up-regulation
CAMK_CAMKL_AMPK_PRKAA2_ST	O00418	EEF2K	P54646	PRKAA2	S386	D387N	387	Missense	proximal	1	no	54.363	54.420	EPSD	TCGA;ICGC	46.832	Up-regulation
CAMK_CAMKL_AMPK_PRKAA2_ST	O00418	EEF2K	P54646	PRKAA2	S386	S392F	392	Missense	distal	6	no	54.363	52.039	EPSD	TCGA;ICGC;COSMIC	46.832	Down-regulation
CAMK_CAMKL_AMPK_PRKAA2_ST	O00418	EEF2K	P54646	PRKAA2	S386	M385T	385	Missense	proximal	-1	no	54.363	54.507	EPSD	TCGA;ICGC	46.832	Up-regulation
CAMK_CAMKL_AMPK_PRKAA2_ST	O00418	EEF2K	P54646	PRKAA2	S386	D391N	391	Missense	distal	5	no	54.363	54.332	EPSD	TCGA;ICGC	46.832	Down-regulation
CAMK_CAMKL_AMPK_PRKAA2_ST	O00418	EEF2K	P54646	PRKAA2	S395	A400V	400	Missense	distal	5	no	65.193	64.992	EPSD	TCGA;ICGC;COSMIC	46.832	Down-regulation
CAMK_CAMKL_AMPK_PRKAA2_ST	O00418	EEF2K	P54646	PRKAA2	S395	S396F	396	Missense	proximal	1	no	65.193	65.100	EPSD	TCGA;ICGC;COSMIC	46.832	Down-regulation
CAMK_CAMKL_AMPK_PRKAA2_ST	O00418	EEF2K	P54646	PRKAA2	S395	S392F	392	Missense	distal	-3	no	65.193	60.511	EPSD	TCGA;ICGC;COSMIC	46.832	Down-regulation
CAMK_CAMKL_AMPK_PRKAA2_ST	O00418	EEF2K	P54646	PRKAA2	S395	D391N	391	Missense	distal	-4	no	65.193	64.521	EPSD	TCGA;ICGC	46.832	Down-regulation
CAMK_CAMKL_AMPK_PRKAA2_ST	O00418	EEF2K	P54646	PRKAA2	S398	A400V	400	Missense	proximal	2	no	66.424	69.593	PhosphoSitePlus	TCGA;ICGC;COSMIC	46.832	Up-regulation
CAMK_CAMKL_AMPK_PRKAA2_ST	O00418	EEF2K	P54646	PRKAA2	S398	S396F	396	Missense	proximal	-2	no	66.424	60.114	PhosphoSitePlus	TCGA;ICGC;COSMIC	46.832	Down-regulation
CAMK_CAMKL_AMPK_PRKAA2_ST	O00418	EEF2K	P54646	PRKAA2	S398	S392F	392	Missense	distal	-6	no	66.424	65.097	PhosphoSitePlus	TCGA;ICGC;COSMIC	46.832	Down-regulation
CAMK_CAMKL_AMPK_PRKAA2_ST	O00418	EEF2K	P54646	PRKAA2	S398	D391N	391	Missense	distal	-7	no	66.424	66.658	PhosphoSitePlus	TCGA;ICGC	46.832	Up-regulation
CAMK_CAMKL_AMPK_PRKAA2_ST	P28562	DUSP1	P54646	PRKAA2	S140	S137R	137	Missense	distal	-3	no	39.807	47.332	EPSD	TCGA;ICGC;COSMIC	46.832	Gain
CAMK_CAMKL_AMPK_PRKAA2_ST	P28562	DUSP1	P54646	PRKAA2	T141	S137R	137	Missense	distal	-4	no	46.858	46.773	EPSD	TCGA;ICGC;COSMIC	46.832	Loss
CAMK_CAMKL_AMPK_PRKAA2_ST	P28562	DUSP1	P54646	PRKAA2	S334	V338M	338	Missense	distal	4	no	71.466	74.711	PhosphoSitePlus	TCGA;ICGC;COSMIC	46.832	Up-regulation
CAMK_CAMKL_AMPK_PRKAA2_ST	P30260	CDC27	P54646	PRKAA2	S296	P292S	292	Missense	distal	-4	no	47.929	47.908	EPSD	TCGA;ICGC;COSMIC	46.832	Down-regulation
CAMK_CAMKL_AMPK_PRKAA2_ST	P30260	CDC27	P54646	PRKAA2	T313	T313I	313	Missense	central	0	yes	51.952	0.000	EPSD	TCGA;ICGC;COSMIC	46.832	Loss
CAMK_CAMKL_AMPK_PRKAA2_ST	P30260	CDC27	P54646	PRKAA2	S320	T313I	313	Missense	distal	-7	no	61.039	60.444	EPSD	TCGA;ICGC;COSMIC	46.832	Down-regulation
CAMK_CAMKL_AMPK_PRKAA2_ST	O43524	FOXO3	P54646	PRKAA2	S75	D68Y	68	Missense	distal	-7	no	48.531	47.848	EPSD	TCGA;ICGC;COSMIC	46.832	Down-regulation
CAMK_CAMKL_AMPK_PRKAA2_ST	O43524	FOXO3	P54646	PRKAA2	S253	R248Q	248	Missense	distal	-5	no	51.904	48.651	EPSD	TCGA;ICGC;COSMIC	46.832	Down-regulation
CAMK_CAMKL_AMPK_PRKAA2_ST	O43524	FOXO3	P54646	PRKAA2	S253	R250W	250	Missense	distal	-3	no	51.904	35.760	EPSD	TCGA;ICGC;COSMIC	46.832	Loss
CAMK_CAMKL_AMPK_PRKAA2_ST	O43524	FOXO3	P54646	PRKAA2	S253	R250Q	250	Missense	distal	-3	no	51.904	37.639	EPSD	TCGA;ICGC;COSMIC	46.832	Loss
CAMK_CAMKL_AMPK_PRKAA2_ST	O43524	FOXO3	P54646	PRKAA2	T296	L303M	303	Missense	distal	7	no	46.238	49.409	EPSD	TCGA;ICGC	46.832	Gain
CAMK_CAMKL_AMPK_PRKAA2_ST	O43524	FOXO3	P54646	PRKAA2	T296	R298C	298	Missense	proximal	2	no	46.238	51.274	EPSD	TCGA;ICGC	46.832	Gain
CAMK_CAMKL_AMPK_PRKAA2_ST	O43524	FOXO3	P54646	PRKAA2	T296	G293D	293	Missense	distal	-3	no	46.238	51.089	EPSD	TCGA;ICGC;COSMIC	46.832	Gain
CAMK_CAMKL_AMPK_PRKAA2_ST	O43524	FOXO3	P54646	PRKAA2	S315	R310C	310	Missense	distal	-5	no	54.324	49.262	EPSD	TCGA;ICGC;COSMIC	46.832	Down-regulation
CAMK_CAMKL_AMPK_PRKAA2_ST	O43524	FOXO3	P54646	PRKAA2	S315	D308Y	308	Missense	distal	-7	no	54.324	53.640	EPSD	TCGA;ICGC;COSMIC	46.832	Down-regulation
CAMK_CAMKL_AMPK_PRKAA2_ST	O43524	FOXO3	P54646	PRKAA2	S315	S315F	315	Missense	central	0	yes	54.324	0.000	EPSD	TCGA;ICGC;COSMIC	46.832	Loss
CAMK_CAMKL_AMPK_PRKAA2_ST	O43524	FOXO3	P54646	PRKAA2	S315	R312C	312	Missense	distal	-3	no	54.324	41.051	EPSD	TCGA;ICGC;COSMIC	46.832	Loss
CAMK_CAMKL_AMPK_PRKAA2_ST	O43524	FOXO3	P54646	PRKAA2	T319	R323L	323	Missense	distal	4	no	52.081	68.567	EPSD	TCGA;ICGC;COSMIC	46.832	Up-regulation
CAMK_CAMKL_AMPK_PRKAA2_ST	O43524	FOXO3	P54646	PRKAA2	T319	S315F	315	Missense	distal	-4	no	52.081	50.845	EPSD	TCGA;ICGC;COSMIC	46.832	Down-regulation
CAMK_CAMKL_AMPK_PRKAA2_ST	O43524	FOXO3	P54646	PRKAA2	T319	R312C	312	Missense	distal	-7	no	52.081	51.777	EPSD	TCGA;ICGC;COSMIC	46.832	Down-regulation
CAMK_CAMKL_AMPK_PRKAA2_ST	O43524	FOXO3	P54646	PRKAA2	T363	R368Q	368	Missense	distal	5	no	49.334	49.370	EPSD	TCGA;ICGC;COSMIC	46.832	Up-regulation
CAMK_CAMKL_AMPK_PRKAA2_ST	O43524	FOXO3	P54646	PRKAA2	T363	C362F	362	Missense	proximal	-1	no	49.334	49.187	EPSD	TCGA;ICGC;COSMIC	46.832	Down-regulation
CAMK_CAMKL_AMPK_PRKAA2_ST	O43524	FOXO3	P54646	PRKAA2	T395	P397S	397	Missense	proximal	2	no	47.132	44.962	EPSD	TCGA;ICGC;COSMIC	46.832	Loss
CAMK_CAMKL_AMPK_PRKAA2_ST	O43524	FOXO3	P54646	PRKAA2	T395	P397L	397	Missense	proximal	2	no	47.132	41.020	EPSD	TCGA;ICGC;COSMIC	46.832	Loss
CAMK_CAMKL_AMPK_PRKAA2_ST	O43524	FOXO3	P54646	PRKAA2	T395	D392G	392	Missense	distal	-3	no	47.132	42.281	EPSD	TCGA;ICGC;COSMIC	46.832	Loss
CAMK_CAMKL_AMPK_PRKAA2_ST	O43524	FOXO3	P54646	PRKAA2	T395	S402L	402	Missense	distal	7	no	47.132	47.553	EPSD	TCGA;ICGC;COSMIC	46.832	Up-regulation
CAMK_CAMKL_AMPK_PRKAA2_ST	O43524	FOXO3	P54646	PRKAA2	S399	P397S	397	Missense	proximal	-2	no	65.379	64.808	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	46.832	Down-regulation
CAMK_CAMKL_AMPK_PRKAA2_ST	O43524	FOXO3	P54646	PRKAA2	S399	P397L	397	Missense	proximal	-2	no	65.379	64.432	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	46.832	Down-regulation
CAMK_CAMKL_AMPK_PRKAA2_ST	O43524	FOXO3	P54646	PRKAA2	S399	D392G	392	Missense	distal	-7	no	65.379	65.219	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	46.832	Down-regulation
CAMK_CAMKL_AMPK_PRKAA2_ST	O43524	FOXO3	P54646	PRKAA2	S399	S402L	402	Missense	distal	3	no	65.379	63.299	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	46.832	Down-regulation
CAMK_CAMKL_AMPK_PRKAA2_ST	O43524	FOXO3	P54646	PRKAA2	S413	S412C	412	Missense	proximal	-1	no	68.510	68.115	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	46.832	Down-regulation
CAMK_CAMKL_AMPK_PRKAA2_ST	O43524	FOXO3	P54646	PRKAA2	S428	L423M	423	Missense	distal	-5	no	47.039	47.913	EPSD	TCGA;ICGC	46.832	Up-regulation
CAMK_CAMKL_AMPK_PRKAA2_ST	O43524	FOXO3	P54646	PRKAA2	S428	S425F	425	Missense	distal	-3	no	47.039	42.357	EPSD	TCGA;ICGC;COSMIC	46.832	Loss
CAMK_CAMKL_AMPK_PRKAA2_ST	O43524	FOXO3	P54646	PRKAA2	S428	V434M	434	Missense	distal	6	no	47.039	49.857	EPSD	TCGA;ICGC;COSMIC	46.832	Up-regulation
CAMK_CAMKL_AMPK_PRKAA2_ST	O43524	FOXO3	P54646	PRKAA2	S429	G436R	436	Missense	distal	7	no	48.023	47.719	EPSD	TCGA;ICGC;COSMIC;GDSC;CCLE	46.832	Down-regulation
CAMK_CAMKL_AMPK_PRKAA2_ST	O43524	FOXO3	P54646	PRKAA2	S429	L423M	423	Missense	distal	-6	no	48.023	47.991	EPSD	TCGA;ICGC	46.832	Down-regulation
CAMK_CAMKL_AMPK_PRKAA2_ST	O43524	FOXO3	P54646	PRKAA2	S429	S425F	425	Missense	distal	-4	no	48.023	46.787	EPSD	TCGA;ICGC;COSMIC	46.832	Loss
CAMK_CAMKL_AMPK_PRKAA2_ST	O43524	FOXO3	P54646	PRKAA2	S429	V434M	434	Missense	distal	5	no	48.023	48.003	EPSD	TCGA;ICGC;COSMIC	46.832	Down-regulation
CAMK_CAMKL_AMPK_PRKAA2_ST	O43524	FOXO3	P54646	PRKAA2	S432	G436R	436	Missense	distal	4	no	49.361	45.927	EPSD	TCGA;ICGC;COSMIC;GDSC;CCLE	46.832	Loss
CAMK_CAMKL_AMPK_PRKAA2_ST	O43524	FOXO3	P54646	PRKAA2	S432	S425F	425	Missense	distal	-7	no	49.361	49.116	EPSD	TCGA;ICGC;COSMIC	46.832	Down-regulation
CAMK_CAMKL_AMPK_PRKAA2_ST	O43524	FOXO3	P54646	PRKAA2	S432	V434M	434	Missense	proximal	2	no	49.361	45.145	EPSD	TCGA;ICGC;COSMIC	46.832	Loss
CAMK_CAMKL_AMPK_PRKAA2_ST	O43524	FOXO3	P54646	PRKAA2	S438	G436R	436	Missense	proximal	-2	no	48.550	51.145	EPSD	TCGA;ICGC;COSMIC;GDSC;CCLE	46.832	Up-regulation
CAMK_CAMKL_AMPK_PRKAA2_ST	O43524	FOXO3	P54646	PRKAA2	S438	V434M	434	Missense	distal	-4	no	48.550	48.107	EPSD	TCGA;ICGC;COSMIC	46.832	Down-regulation
CAMK_CAMKL_AMPK_PRKAA2_ST	O43524	FOXO3	P54646	PRKAA2	S439	G436R	436	Missense	distal	-3	no	54.748	66.683	EPSD	TCGA;ICGC;COSMIC;GDSC;CCLE	46.832	Up-regulation
CAMK_CAMKL_AMPK_PRKAA2_ST	O43524	FOXO3	P54646	PRKAA2	S439	V434M	434	Missense	distal	-5	no	54.748	60.351	EPSD	TCGA;ICGC;COSMIC	46.832	Up-regulation
CAMK_CAMKL_AMPK_PRKAA2_ST	O43524	FOXO3	P54646	PRKAA2	S442	G436R	436	Missense	distal	-6	no	52.593	52.753	EPSD	TCGA;ICGC;COSMIC;GDSC;CCLE	46.832	Up-regulation
CAMK_CAMKL_AMPK_PRKAA2_ST	O43524	FOXO3	P54646	PRKAA2	S442	Q449H	449	Missense	distal	7	no	52.593	53.070	EPSD	TCGA;ICGC;COSMIC	46.832	Up-regulation
CAMK_CAMKL_AMPK_PRKAA2_ST	O43524	FOXO3	P54646	PRKAA2	S446	Q449H	449	Missense	distal	3	no	49.138	48.153	EPSD	TCGA;ICGC;COSMIC	46.832	Down-regulation
CAMK_CAMKL_AMPK_PRKAA2_ST	O43524	FOXO3	P54646	PRKAA2	S551	S553Y	553	Missense	proximal	2	no	54.803	36.206	EPSD	TCGA;ICGC;COSMIC	46.832	Loss
CAMK_CAMKL_AMPK_PRKAA2_ST	O43524	FOXO3	P54646	PRKAA2	S555	S560I	560	Missense	distal	5	no	66.106	65.921	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	46.832	Down-regulation
CAMK_CAMKL_AMPK_PRKAA2_ST	O43524	FOXO3	P54646	PRKAA2	S555	S553Y	553	Missense	proximal	-2	no	66.106	62.546	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	46.832	Down-regulation
CAMK_CAMKL_AMPK_PRKAA2_ST	O43524	FOXO3	P54646	PRKAA2	S588	D585A	585	Missense	distal	-3	no	75.453	69.704	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	46.832	Down-regulation
CAMK_CAMKL_AMPK_PRKAA2_ST	P08151	GLI1	P54646	PRKAA2	S84	I85M	85	Missense	proximal	1	no	47.664	47.690	EPSD	TCGA;COSMIC	46.832	Up-regulation
CAMK_CAMKL_AMPK_PRKAA2_ST	P08151	GLI1	P54646	PRKAA2	S84	R81L	81	Missense	distal	-3	no	47.664	36.709	EPSD	TCGA;COSMIC	46.832	Loss
CAMK_CAMKL_AMPK_PRKAA2_ST	P08151	GLI1	P54646	PRKAA2	S84	S89L	89	Missense	distal	5	no	47.664	47.722	EPSD	TCGA;COSMIC	46.832	Up-regulation
CAMK_CAMKL_AMPK_PRKAA2_ST	P08151	GLI1	P54646	PRKAA2	S84	S84P	84	Missense	central	0	yes	47.664	0.000	EPSD	TCGA;COSMIC	46.832	Loss
CAMK_CAMKL_AMPK_PRKAA2_ST	P08151	GLI1	P54646	PRKAA2	S84	R81W	81	Missense	distal	-3	no	47.664	31.521	EPSD	TCGA;COSMIC	46.832	Loss
CAMK_CAMKL_AMPK_PRKAA2_ST	P08151	GLI1	P54646	PRKAA2	S84	R81Q	81	Missense	distal	-3	no	47.664	33.399	EPSD	TCGA;COSMIC	46.832	Loss
CAMK_CAMKL_AMPK_PRKAA2_ST	P08151	GLI1	P54646	PRKAA2	S84	K79N	79	Missense	distal	-5	no	47.664	57.825	EPSD	TCGA;COSMIC	46.832	Up-regulation
CAMK_CAMKL_AMPK_PRKAA2_ST	P08151	GLI1	P54646	PRKAA2	S89	I85M	85	Missense	distal	-4	no	54.351	54.655	EPSD	TCGA;COSMIC	46.832	Up-regulation
CAMK_CAMKL_AMPK_PRKAA2_ST	P08151	GLI1	P54646	PRKAA2	S89	S89L	89	Missense	central	0	yes	54.351	0.000	EPSD	TCGA;COSMIC	46.832	Loss
CAMK_CAMKL_AMPK_PRKAA2_ST	P08151	GLI1	P54646	PRKAA2	S89	S84P	84	Missense	distal	-5	no	54.351	51.966	EPSD	TCGA;COSMIC	46.832	Down-regulation
CAMK_CAMKL_AMPK_PRKAA2_ST	P08151	GLI1	P54646	PRKAA2	S89	D94Y	94	Missense	distal	5	no	54.351	53.837	EPSD	TCGA;COSMIC	46.832	Down-regulation
CAMK_CAMKL_AMPK_PRKAA2_ST	P08151	GLI1	P54646	PRKAA2	S102	R100C	100	Missense	proximal	-2	no	69.119	66.959	EPSD;PhosphoSitePlus	TCGA;COSMIC	46.832	Down-regulation
CAMK_CAMKL_AMPK_PRKAA2_ST	P08151	GLI1	P54646	PRKAA2	S102	V107L	107	Missense	distal	5	no	69.119	69.356	EPSD;PhosphoSitePlus	TCGA;COSMIC	46.832	Up-regulation
CAMK_CAMKL_AMPK_PRKAA2_ST	P08151	GLI1	P54646	PRKAA2	S102	T97M	97	Missense	distal	-5	no	69.119	71.473	EPSD;PhosphoSitePlus	TCGA;COSMIC	46.832	Up-regulation
CAMK_CAMKL_AMPK_PRKAA2_ST	P08151	GLI1	P54646	PRKAA2	T205	S200C	200	Missense	distal	-5	no	47.728	36.979	EPSD	TCGA;COSMIC	46.832	Loss
CAMK_CAMKL_AMPK_PRKAA2_ST	P08151	GLI1	P54646	PRKAA2	T205	D209Y	209	Missense	distal	4	no	47.728	32.544	EPSD	TCGA;COSMIC	46.832	Loss
CAMK_CAMKL_AMPK_PRKAA2_ST	P08151	GLI1	P54646	PRKAA2	T205	P210S	210	Missense	distal	5	no	47.728	47.855	EPSD	TCGA;COSMIC	46.832	Up-regulation
CAMK_CAMKL_AMPK_PRKAA2_ST	P08151	GLI1	P54646	PRKAA2	T205	Q208H	208	Missense	distal	3	no	47.728	46.744	EPSD	TCGA;COSMIC	46.832	Loss
CAMK_CAMKL_AMPK_PRKAA2_ST	P08151	GLI1	P54646	PRKAA2	S408	R405G	405	Missense	distal	-3	no	68.083	56.148	PhosphoSitePlus;EPSD	TCGA;COSMIC	46.832	Down-regulation
CAMK_CAMKL_AMPK_PRKAA2_ST	P08151	GLI1	P54646	PRKAA2	S408	R405W	405	Missense	distal	-3	no	68.083	51.939	PhosphoSitePlus;EPSD	TCGA;COSMIC	46.832	Down-regulation
CAMK_CAMKL_AMPK_PRKAA2_ST	P08151	GLI1	P54646	PRKAA2	S410	R405G	405	Missense	distal	-5	no	40.398	46.975	EPSD	TCGA;COSMIC	46.832	Gain
CAMK_CAMKL_AMPK_PRKAA2_ST	P08151	GLI1	P54646	PRKAA2	S521	R515W	515	Missense	distal	-6	no	55.210	54.881	EPSD	TCGA;COSMIC	46.832	Down-regulation
CAMK_CAMKL_AMPK_PRKAA2_ST	P08151	GLI1	P54646	PRKAA2	T527	R531L	531	Missense	distal	4	no	36.212	52.699	EPSD	TCGA;COSMIC	46.832	Gain
CAMK_CAMKL_AMPK_PRKAA2_ST	P08151	GLI1	P54646	PRKAA2	S545	R541H	541	Missense	distal	-4	no	59.044	58.258	EPSD	TCGA;COSMIC	46.832	Down-regulation
CAMK_CAMKL_AMPK_PRKAA2_ST	P08151	GLI1	P54646	PRKAA2	S545	E540K	540	Missense	distal	-5	no	59.044	52.395	EPSD	TCGA;COSMIC	46.832	Down-regulation
CAMK_CAMKL_AMPK_PRKAA2_ST	P08151	GLI1	P54646	PRKAA2	S545	S543N	543	Missense	proximal	-2	no	59.044	56.776	EPSD	TCGA;COSMIC	46.832	Down-regulation
CAMK_CAMKL_AMPK_PRKAA2_ST	P08151	GLI1	P54646	PRKAA2	S545	L539P	539	Missense	distal	-6	no	59.044	59.640	EPSD	TCGA	46.832	Up-regulation
CAMK_CAMKL_AMPK_PRKAA2_ST	P08151	GLI1	P54646	PRKAA2	S937	V936A	936	Missense	proximal	-1	no	48.235	48.419	EPSD	TCGA;COSMIC	46.832	Up-regulation
CAMK_CAMKL_AMPK_PRKAA2_ST	P08151	GLI1	P54646	PRKAA2	S937	L931M	931	Missense	distal	-6	no	48.235	48.204	EPSD	TCGA;COSMIC	46.832	Down-regulation
CAMK_CAMKL_AMPK_PRKAA2_ST	P08151	GLI1	P54646	PRKAA2	S937	R940H	940	Missense	distal	3	no	48.235	51.199	EPSD	TCGA;GDSC;CCLE	46.832	Up-regulation
CAMK_CAMKL_AMPK_PRKAA2_ST	P08151	GLI1	P54646	PRKAA2	S1071	S1064F	1064	Missense	distal	-7	no	47.458	47.212	EPSD	TCGA;ICGC;COSMIC	46.832	Down-regulation
CAMK_CAMKL_AMPK_PRKAA2_ST	P08151	GLI1	P54646	PRKAA2	S1071	P1077L	1077	Missense	distal	6	no	47.458	49.386	EPSD	TCGA;COSMIC	46.832	Up-regulation
CAMK_CAMKL_AMPK_PRKAA2_ST	P08151	GLI1	P54646	PRKAA2	S1071	G1069S	1069	Missense	proximal	-2	no	47.458	49.882	EPSD	TCGA;COSMIC	46.832	Up-regulation
CAMK_CAMKL_AMPK_PRKAA2_ST	P08151	GLI1	P54646	PRKAA2	S1071	S1070N	1070	Missense	proximal	-1	no	47.458	47.552	EPSD	TCGA	46.832	Up-regulation
CAMK_CAMKL_AMPK_PRKAA2_ST	P08151	GLI1	P54646	PRKAA2	T1074	P1077L	1077	Missense	distal	3	no	66.875	68.531	EPSD;PhosphoSitePlus	TCGA;COSMIC	46.832	Up-regulation
CAMK_CAMKL_AMPK_PRKAA2_ST	P08151	GLI1	P54646	PRKAA2	T1074	G1069S	1069	Missense	distal	-5	no	66.875	65.987	EPSD;PhosphoSitePlus	TCGA;COSMIC	46.832	Down-regulation
CAMK_CAMKL_AMPK_PRKAA2_ST	P08151	GLI1	P54646	PRKAA2	T1074	S1070N	1070	Missense	distal	-4	no	66.875	65.939	EPSD;PhosphoSitePlus	TCGA	46.832	Down-regulation
CAMK_CAMKL_AMPK_PRKAA2_ST	Q9BZL4	PPP1R12C	P54646	PRKAA2	T290	G284R	284	Missense	distal	-6	no	51.675	51.835	EPSD	TCGA;ICGC	46.832	Up-regulation
CAMK_CAMKL_AMPK_PRKAA2_ST	Q9BZL4	PPP1R12C	P54646	PRKAA2	S325	R328W	328	Missense	distal	3	no	53.368	55.073	EPSD	TCGA;ICGC;COSMIC	46.832	Up-regulation
CAMK_CAMKL_AMPK_PRKAA2_ST	Q9BZL4	PPP1R12C	P54646	PRKAA2	S325	R319W	319	Missense	distal	-6	no	53.368	53.039	EPSD	TCGA;ICGC;COSMIC	46.832	Down-regulation
CAMK_CAMKL_AMPK_PRKAA2_ST	Q9BZL4	PPP1R12C	P54646	PRKAA2	S344	R351H	351	Missense	distal	7	no	55.060	54.685	EPSD	TCGA;ICGC;COSMIC	46.832	Down-regulation
CAMK_CAMKL_AMPK_PRKAA2_ST	Q9BZL4	PPP1R12C	P54646	PRKAA2	S399	K406E	406	Missense	distal	7	no	54.644	54.953	EPSD	TCGA;ICGC	46.832	Up-regulation
CAMK_CAMKL_AMPK_PRKAA2_ST	Q9BZL4	PPP1R12C	P54646	PRKAA2	S399	P400S	400	Missense	proximal	1	no	54.644	54.745	EPSD	TCGA;ICGC;COSMIC	46.832	Up-regulation
CAMK_CAMKL_AMPK_PRKAA2_ST	Q9BZL4	PPP1R12C	P54646	PRKAA2	S399	V397I	397	Missense	proximal	-2	no	54.644	55.300	EPSD	TCGA;ICGC;COSMIC	46.832	Up-regulation
CAMK_CAMKL_AMPK_PRKAA2_ST	Q9BZL4	PPP1R12C	P54646	PRKAA2	S509	P507L	507	Missense	proximal	-2	no	55.078	54.131	EPSD	TCGA	46.832	Down-regulation
CAMK_CAMKL_AMPK_PRKAA2_ST	Q9BZL4	PPP1R12C	P54646	PRKAA2	S509	P505L	505	Missense	distal	-4	no	55.078	53.345	EPSD	TCGA;ICGC;COSMIC;GDSC;CCLE	46.832	Down-regulation
CAMK_CAMKL_AMPK_PRKAA2_ST	Q9BZL4	PPP1R12C	P54646	PRKAA2	S509	P505A	505	Missense	distal	-4	no	55.078	53.667	EPSD	TCGA;ICGC;COSMIC	46.832	Down-regulation
CAMK_CAMKL_AMPK_PRKAA2_ST	Q9BZL4	PPP1R12C	P54646	PRKAA2	S559	R554H	554	Missense	distal	-5	no	49.854	36.245	EPSD	TCGA;ICGC;COSMIC	46.832	Loss
CAMK_CAMKL_AMPK_PRKAA2_ST	Q9BZL4	PPP1R12C	P54646	PRKAA2	S559	Q561P	561	Missense	proximal	2	no	49.854	59.318	EPSD	TCGA;ICGC;COSMIC	46.832	Up-regulation
CAMK_CAMKL_AMPK_PRKAA2_ST	Q9BZL4	PPP1R12C	P54646	PRKAA2	S559	R558K	558	Missense	proximal	-1	no	49.854	49.708	EPSD	TCGA;ICGC;COSMIC	46.832	Down-regulation
CAMK_CAMKL_AMPK_PRKAA2_ST	Q9BZL4	PPP1R12C	P54646	PRKAA2	S559	R557W	557	Missense	proximal	-2	no	49.854	42.858	EPSD	TCGA;ICGC	46.832	Loss
CAMK_CAMKL_AMPK_PRKAA2_ST	Q9BZL4	PPP1R12C	P54646	PRKAA2	S559	L565P	565	Missense	distal	6	no	49.854	47.926	EPSD	TCGA;ICGC;COSMIC	46.832	Down-regulation
CAMK_CAMKL_AMPK_PRKAA2_ST	Q9BZL4	PPP1R12C	P54646	PRKAA2	S559	T564P	564	Missense	distal	5	no	49.854	49.983	EPSD	TCGA;ICGC	46.832	Up-regulation
CAMK_CAMKL_AMPK_PRKAA2_ST	Q9BZL4	PPP1R12C	P54646	PRKAA2	T564	Q561P	561	Missense	distal	-3	no	42.766	48.120	EPSD	TCGA;ICGC;COSMIC	46.832	Gain
CAMK_CAMKL_AMPK_PRKAA2_ST	Q9BXM7	PINK1	P54646	PRKAA2	S228	E231K	231	Missense	distal	3	no	65.909	65.067	PhosphoSitePlus;EPSD	TCGA;ICGC;COSMIC	46.832	Down-regulation
CAMK_CAMKL_AMPK_PRKAA2_ST	Q9BXM7	PINK1	P54646	PRKAA2	S228	S225P	225	Missense	distal	-3	no	65.909	64.523	PhosphoSitePlus;EPSD	TCGA;ICGC;COSMIC	46.832	Down-regulation
CAMK_CAMKL_AMPK_PRKAA2_ST	Q9BXM7	PINK1	P54646	PRKAA2	S284	P286S	286	Missense	proximal	2	no	70.151	67.981	EPSD;PhosphoSitePlus	TCGA;ICGC	46.832	Down-regulation
CAMK_CAMKL_AMPK_PRKAA2_ST	Q9BXM7	PINK1	P54646	PRKAA2	S284	L278I	278	Missense	distal	-6	no	70.151	69.733	EPSD;PhosphoSitePlus	TCGA;ICGC	46.832	Down-regulation
CAMK_CAMKL_AMPK_PRKAA2_ST	Q9BXM7	PINK1	P54646	PRKAA2	S495	R492Q	492	Missense	distal	-3	no	68.340	54.075	EPSD;PhosphoSitePlus	TCGA	46.832	Down-regulation
CAMK_CAMKL_AMPK_PRKAA2_ST	Q9BXM7	PINK1	P54646	PRKAA2	S495	A494T	494	Missense	proximal	-1	no	68.340	68.109	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	46.832	Down-regulation
CAMK_CAMKL_AMPK_PRKAA2_ST	Q92819	HAS2	P54646	PRKAA2	T110	V106L	106	Missense	distal	-4	no	64.631	63.867	PhosphoSitePlus	TCGA	46.832	Down-regulation
CAMK_CAMKL_AMPK_PRKAA2_ST	Q92819	HAS2	P54646	PRKAA2	S334	E339K	339	Missense	distal	5	no	50.856	50.864	EPSD	TCGA;ICGC;COSMIC	46.832	Up-regulation
CAMK_CAMKL_AMPK_PRKAA2_ST	Q92819	HAS2	P54646	PRKAA2	S334	T331I	331	Missense	distal	-3	no	50.856	47.776	EPSD	TCGA;ICGC;COSMIC	46.832	Down-regulation
CAMK_CAMKL_AMPK_PRKAA2_ST	Q92819	HAS2	P54646	PRKAA2	S334	T338I	338	Missense	distal	4	no	50.856	48.369	EPSD	TCGA;ICGC;COSMIC	46.832	Down-regulation
CAMK_CAMKL_AMPK_PRKAA2_ST	Q92819	HAS2	P54646	PRKAA2	S334	S334F	334	Missense	central	0	yes	50.856	0.000	EPSD	TCGA;ICGC;COSMIC	46.832	Loss
CAMK_CAMKL_AMPK_PRKAA2_ST	Q92819	HAS2	P54646	PRKAA2	S445	P449L	449	Missense	distal	4	no	41.368	49.702	EPSD	TCGA;ICGC;COSMIC	46.832	Gain
CAMK_CAMKL_AMPK_PRKAA2_ST	Q9UQB8	BAIAP2	P54646	PRKAA2	S259	A257V	257	Missense	proximal	-2	no	55.506	52.609	EPSD	TCGA;COSMIC	46.832	Down-regulation
CAMK_CAMKL_AMPK_PRKAA2_ST	Q9UQB8	BAIAP2	P54646	PRKAA2	S259	P255L	255	Missense	distal	-4	no	55.506	53.774	EPSD	TCGA;COSMIC	46.832	Down-regulation
CAMK_CAMKL_AMPK_PRKAA2_ST	Q9UQB8	BAIAP2	P54646	PRKAA2	S259	L258R	258	Missense	proximal	-1	no	55.506	55.135	EPSD	TCGA;COSMIC	46.832	Down-regulation
CAMK_CAMKL_AMPK_PRKAA2_ST	Q9UQB8	BAIAP2	P54646	PRKAA2	S261	A257V	257	Missense	distal	-4	no	54.374	54.816	EPSD	TCGA;COSMIC	46.832	Up-regulation
CAMK_CAMKL_AMPK_PRKAA2_ST	Q9UQB8	BAIAP2	P54646	PRKAA2	S261	P255L	255	Missense	distal	-6	no	54.374	53.778	EPSD	TCGA;COSMIC	46.832	Down-regulation
CAMK_CAMKL_AMPK_PRKAA2_ST	Q9UQB8	BAIAP2	P54646	PRKAA2	S261	L258R	258	Missense	distal	-3	no	54.374	65.330	EPSD	TCGA;COSMIC	46.832	Up-regulation
CAMK_CAMKL_AMPK_PRKAA2_ST	Q9UQB8	BAIAP2	P54646	PRKAA2	S291	R289W	289	Missense	proximal	-2	no	49.144	42.148	EPSD	TCGA;COSMIC	46.832	Loss
CAMK_CAMKL_AMPK_PRKAA2_ST	Q9UQB8	BAIAP2	P54646	PRKAA2	S291	E294K	294	Missense	distal	3	no	49.144	48.302	EPSD	TCGA	46.832	Down-regulation
CAMK_CAMKL_AMPK_PRKAA2_ST	Q9UQB8	BAIAP2	P54646	PRKAA2	S295	R289W	289	Missense	distal	-6	no	50.843	50.514	EPSD	TCGA;COSMIC	46.832	Down-regulation
CAMK_CAMKL_AMPK_PRKAA2_ST	Q9UQB8	BAIAP2	P54646	PRKAA2	S295	G301S	301	Missense	distal	6	no	50.843	51.935	EPSD	TCGA;COSMIC	46.832	Up-regulation
CAMK_CAMKL_AMPK_PRKAA2_ST	Q9UQB8	BAIAP2	P54646	PRKAA2	S295	E294K	294	Missense	proximal	-1	no	50.843	50.622	EPSD	TCGA	46.832	Down-regulation
CAMK_CAMKL_AMPK_PRKAA2_ST	Q9UQB8	BAIAP2	P54646	PRKAA2	S323	K322E	322	Missense	proximal	-1	no	49.561	49.782	EPSD	TCGA;COSMIC	46.832	Up-regulation
CAMK_CAMKL_AMPK_PRKAA2_ST	Q9UQB8	BAIAP2	P54646	PRKAA2	S323	S325P	325	Missense	proximal	2	no	49.561	51.732	EPSD	TCGA;COSMIC	46.832	Up-regulation
CAMK_CAMKL_AMPK_PRKAA2_ST	Q9UQB8	BAIAP2	P54646	PRKAA2	S323	P327S	327	Missense	distal	4	no	49.561	51.410	EPSD	TCGA;COSMIC	46.832	Up-regulation
CAMK_CAMKL_AMPK_PRKAA2_ST	Q9UQB8	BAIAP2	P54646	PRKAA2	S323	P327L	327	Missense	distal	4	no	49.561	57.895	EPSD	TCGA;COSMIC;GDSC	46.832	Up-regulation
CAMK_CAMKL_AMPK_PRKAA2_ST	Q9UQB8	BAIAP2	P54646	PRKAA2	S323	A318V	318	Missense	distal	-5	no	49.561	46.916	EPSD	TCGA;COSMIC	46.832	Down-regulation
CAMK_CAMKL_AMPK_PRKAA2_ST	Q9UQB8	BAIAP2	P54646	PRKAA2	S325	K322E	322	Missense	distal	-3	no	53.701	45.328	EPSD	TCGA;COSMIC	46.832	Loss
CAMK_CAMKL_AMPK_PRKAA2_ST	Q9UQB8	BAIAP2	P54646	PRKAA2	S325	S325P	325	Missense	central	0	yes	53.701	0.000	EPSD	TCGA;COSMIC	46.832	Loss
CAMK_CAMKL_AMPK_PRKAA2_ST	Q9UQB8	BAIAP2	P54646	PRKAA2	S325	P327S	327	Missense	proximal	2	no	53.701	51.531	EPSD	TCGA;COSMIC	46.832	Down-regulation
CAMK_CAMKL_AMPK_PRKAA2_ST	Q9UQB8	BAIAP2	P54646	PRKAA2	S325	P327L	327	Missense	proximal	2	no	53.701	47.589	EPSD	TCGA;COSMIC;GDSC	46.832	Down-regulation
CAMK_CAMKL_AMPK_PRKAA2_ST	Q9UQB8	BAIAP2	P54646	PRKAA2	S325	A318V	318	Missense	distal	-7	no	53.701	53.525	EPSD	TCGA;COSMIC	46.832	Down-regulation
CAMK_CAMKL_AMPK_PRKAA2_ST	Q9UQB8	BAIAP2	P54646	PRKAA2	S329	K322E	322	Missense	distal	-7	no	55.272	55.077	EPSD	TCGA;COSMIC	46.832	Down-regulation
CAMK_CAMKL_AMPK_PRKAA2_ST	Q9UQB8	BAIAP2	P54646	PRKAA2	S329	S325P	325	Missense	distal	-4	no	55.272	55.293	EPSD	TCGA;COSMIC	46.832	Up-regulation
CAMK_CAMKL_AMPK_PRKAA2_ST	Q9UQB8	BAIAP2	P54646	PRKAA2	S329	S336F	336	Missense	distal	7	no	55.272	57.187	EPSD	TCGA;COSMIC	46.832	Up-regulation
CAMK_CAMKL_AMPK_PRKAA2_ST	Q9UQB8	BAIAP2	P54646	PRKAA2	S329	P327S	327	Missense	proximal	-2	no	55.272	54.700	EPSD	TCGA;COSMIC	46.832	Down-regulation
CAMK_CAMKL_AMPK_PRKAA2_ST	Q9UQB8	BAIAP2	P54646	PRKAA2	S329	P327L	327	Missense	proximal	-2	no	55.272	54.324	EPSD	TCGA;COSMIC;GDSC	46.832	Down-regulation
CAMK_CAMKL_AMPK_PRKAA2_ST	Q9UQB8	BAIAP2	P54646	PRKAA2	S329	S336P	336	Missense	distal	7	no	55.272	57.421	EPSD	TCGA;COSMIC	46.832	Up-regulation
CAMK_CAMKL_AMPK_PRKAA2_ST	Q9UQB8	BAIAP2	P54646	PRKAA2	S334	S336F	336	Missense	proximal	2	no	57.884	43.673	EPSD	TCGA;COSMIC	46.832	Loss
CAMK_CAMKL_AMPK_PRKAA2_ST	Q9UQB8	BAIAP2	P54646	PRKAA2	S334	P327S	327	Missense	distal	-7	no	57.884	58.030	EPSD	TCGA;COSMIC	46.832	Up-regulation
CAMK_CAMKL_AMPK_PRKAA2_ST	Q9UQB8	BAIAP2	P54646	PRKAA2	S334	P327L	327	Missense	distal	-7	no	57.884	57.910	EPSD	TCGA;COSMIC;GDSC	46.832	Up-regulation
CAMK_CAMKL_AMPK_PRKAA2_ST	Q9UQB8	BAIAP2	P54646	PRKAA2	S334	S336P	336	Missense	proximal	2	no	57.884	60.054	EPSD	TCGA;COSMIC	46.832	Up-regulation
CAMK_CAMKL_AMPK_PRKAA2_ST	Q9UQB8	BAIAP2	P54646	PRKAA2	S336	P342L	342	Missense	distal	6	no	53.770	55.699	EPSD	TCGA;COSMIC	46.832	Up-regulation
CAMK_CAMKL_AMPK_PRKAA2_ST	Q9UQB8	BAIAP2	P54646	PRKAA2	S336	S336F	336	Missense	central	0	yes	53.770	0.000	EPSD	TCGA;COSMIC	46.832	Loss
CAMK_CAMKL_AMPK_PRKAA2_ST	Q9UQB8	BAIAP2	P54646	PRKAA2	S336	S336P	336	Missense	central	0	yes	53.770	0.000	EPSD	TCGA;COSMIC	46.832	Loss
CAMK_CAMKL_AMPK_PRKAA2_ST	Q9UQB8	BAIAP2	P54646	PRKAA2	S338	P342L	342	Missense	distal	4	no	41.520	49.853	EPSD	TCGA;COSMIC	46.832	Gain
CAMK_CAMKL_AMPK_PRKAA2_ST	Q9UQB8	BAIAP2	P54646	PRKAA2	T360	S366F	366	Missense	distal	6	no	49.934	47.610	EPSD	TCGA;COSMIC	46.832	Down-regulation
CAMK_CAMKL_AMPK_PRKAA2_ST	Q9UQB8	BAIAP2	P54646	PRKAA2	S366	S366F	366	Missense	central	0	yes	65.938	0.000	PhosphoSitePlus	TCGA;COSMIC	46.832	Loss
CAMK_CAMKL_AMPK_PRKAA2_ST	Q9UQB8	BAIAP2	P54646	PRKAA2	S366	L371P	371	Missense	distal	5	no	65.938	65.755	PhosphoSitePlus	TCGA;COSMIC	46.832	Down-regulation
CAMK_CAMKL_AMPK_PRKAA2_ST	Q9UQB8	BAIAP2	P54646	PRKAA2	T392	S391N	391	Missense	proximal	-1	no	52.040	52.135	EPSD	TCGA;COSMIC	46.832	Up-regulation
CAMK_CAMKL_AMPK_PRKAA2_ST	Q9UQB8	BAIAP2	P54646	PRKAA2	T392	A386T	386	Missense	distal	-6	no	52.040	52.882	EPSD	TCGA;COSMIC	46.832	Up-regulation
CAMK_CAMKL_AMPK_PRKAA2_ST	Q9UQB8	BAIAP2	P54646	PRKAA2	S452	S446C	446	Missense	distal	-6	no	49.826	47.794	EPSD	TCGA	46.832	Down-regulation
CAMK_CAMKL_AMPK_PRKAA2_ST	Q9UQB8	BAIAP2	P54646	PRKAA2	S452	K451E	451	Missense	proximal	-1	no	49.826	50.046	EPSD	TCGA;ICGC;COSMIC	46.832	Up-regulation
CAMK_CAMKL_AMPK_PRKAA2_ST	Q9UQB8	BAIAP2	P54646	PRKAA2	S452	L459M	459	Missense	distal	7	no	49.826	52.996	EPSD	TCGA;ICGC	46.832	Up-regulation
CAMK_CAMKL_AMPK_PRKAA2_ST	Q13177	PAK2	P54646	PRKAA2	S19	P12A	12	Missense	distal	-7	no	48.254	48.281	EPSD	TCGA;ICGC;COSMIC	46.832	Up-regulation
CAMK_CAMKL_AMPK_PRKAA2_ST	Q13177	PAK2	P54646	PRKAA2	S19	M18K	18	Missense	proximal	-1	no	48.254	48.203	EPSD	TCGA;ICGC;COSMIC	46.832	Down-regulation
CAMK_CAMKL_AMPK_PRKAA2_ST	Q13177	PAK2	P54646	PRKAA2	S20	M18K	18	Missense	proximal	-2	no	62.155	62.588	PhosphoSitePlus	TCGA;ICGC;COSMIC	46.832	Up-regulation
CAMK_CAMKL_AMPK_PRKAA2_ST	Q13177	PAK2	P54646	PRKAA2	T21	M18K	18	Missense	distal	-3	no	38.914	48.399	EPSD	TCGA;ICGC;COSMIC	46.832	Gain
CAMK_CAMKL_AMPK_PRKAA2_ST	Q13177	PAK2	P54646	PRKAA2	T195	T190A	190	Missense	distal	-5	no	51.250	50.648	EPSD	TCGA;ICGC;COSMIC	46.832	Down-regulation
CAMK_CAMKL_AMPK_PRKAA2_ST	Q13177	PAK2	P54646	PRKAA2	T238	E234D	234	Missense	distal	-4	no	55.175	56.529	EPSD	TCGA;ICGC;COSMIC	46.832	Up-regulation
CAMK_CAMKL_AMPK_PRKAA2_ST	Q13177	PAK2	P54646	PRKAA2	S398	R400P	400	Missense	proximal	2	no	50.360	55.657	EPSD	TCGA;ICGC;COSMIC	46.832	Up-regulation
CAMK_CAMKL_AMPK_PRKAA2_ST	Q13177	PAK2	P54646	PRKAA2	S398	R400H	400	Missense	proximal	2	no	50.360	43.872	EPSD	TCGA;ICGC;COSMIC	46.832	Loss
CAMK_CAMKL_AMPK_PRKAA2_ST	Q13177	PAK2	P54646	PRKAA2	S398	E396G	396	Missense	proximal	-2	no	50.360	50.692	EPSD	TCGA;ICGC;COSMIC	46.832	Up-regulation
CAMK_CAMKL_AMPK_PRKAA2_ST	Q13177	PAK2	P54646	PRKAA2	S398	R400C	400	Missense	proximal	2	no	50.360	55.397	EPSD	TCGA;ICGC;COSMIC	46.832	Up-regulation
CAMK_CAMKL_AMPK_PRKAA2_ST	Q13177	PAK2	P54646	PRKAA2	S507	L509F	509	Missense	proximal	2	no	58.874	48.604	EPSD	TCGA;ICGC;COSMIC	46.832	Down-regulation
CAMK_CAMKL_AMPK_PRKAA2_ST	Q13177	PAK2	P54646	PRKAA2	S507	M514I	514	Missense	distal	7	no	58.874	56.746	EPSD	TCGA;ICGC;COSMIC	46.832	Down-regulation
CAMK_CAMKL_AMPK_PRKAA2_ST	Q13177	PAK2	P54646	PRKAA2	S507	P505L	505	Missense	proximal	-2	no	58.874	57.926	EPSD	TCGA;ICGC;COSMIC	46.832	Down-regulation
CAMK_CAMKL_AMPK_PRKAA2_ST	Q13177	PAK2	P54646	PRKAA2	S507	A503V	503	Missense	distal	-4	no	58.874	59.316	EPSD	TCGA;ICGC;COSMIC	46.832	Up-regulation
CAMK_CAMKL_AMPK_PRKAA2_ST	Q13177	PAK2	P54646	PRKAA2	T510	P505L	505	Missense	distal	-5	no	40.619	47.494	EPSD	TCGA;ICGC;COSMIC	46.832	Gain
CAMK_CAMKL_AMPK_PRKAA2_ST	O14920	IKBKB	P54646	PRKAA2	S177	G176D	176	Missense	proximal	-1	no	74.270	73.928	PhosphoSitePlus;EPSD	TCGA;COSMIC	46.832	Down-regulation
CAMK_CAMKL_AMPK_PRKAA2_ST	O14920	IKBKB	P54646	PRKAA2	S177	K171R	171	Missense	distal	-6	no	74.270	74.016	PhosphoSitePlus;EPSD	TCGA;COSMIC	46.832	Down-regulation
CAMK_CAMKL_AMPK_PRKAA2_ST	O14920	IKBKB	P54646	PRKAA2	S177	V183M	183	Missense	distal	6	no	74.270	77.088	PhosphoSitePlus;EPSD	TCGA;COSMIC	46.832	Up-regulation
CAMK_CAMKL_AMPK_PRKAA2_ST	O14920	IKBKB	P54646	PRKAA2	S181	G176D	176	Missense	distal	-5	no	67.182	60.474	EPSD;PhosphoSitePlus	TCGA;COSMIC	46.832	Down-regulation
CAMK_CAMKL_AMPK_PRKAA2_ST	O14920	IKBKB	P54646	PRKAA2	S181	V183M	183	Missense	proximal	2	no	67.182	62.966	EPSD;PhosphoSitePlus	TCGA;COSMIC	46.832	Down-regulation
CAMK_CAMKL_AMPK_PRKAA2_ST	O14920	IKBKB	P54646	PRKAA2	T368	P363R	363	Missense	distal	-5	no	51.577	48.273	EPSD	TCGA;COSMIC	46.832	Down-regulation
CAMK_CAMKL_AMPK_PRKAA2_ST	O14920	IKBKB	P54646	PRKAA2	T368	P363L	363	Missense	distal	-5	no	51.577	58.452	EPSD	TCGA;COSMIC	46.832	Up-regulation
CAMK_CAMKL_AMPK_PRKAA2_ST	O14920	IKBKB	P54646	PRKAA2	S675	R680Q	680	Missense	distal	5	no	50.915	50.950	EPSD	TCGA;COSMIC	46.832	Up-regulation
CAMK_CAMKL_AMPK_PRKAA2_ST	O14920	IKBKB	P54646	PRKAA2	S689	Q690E	690	Missense	proximal	1	no	47.393	47.439	EPSD	TCGA;COSMIC	46.832	Up-regulation
CAMK_CAMKL_AMPK_PRKAA2_ST	O14920	IKBKB	P54646	PRKAA2	S689	S689C	689	Missense	central	0	yes	47.393	0.000	EPSD	TCGA;COSMIC	46.832	Loss
CAMK_CAMKL_AMPK_PRKAA2_ST	O14920	IKBKB	P54646	PRKAA2	S689	A694T	694	Missense	distal	5	no	47.393	47.115	EPSD	TCGA	46.832	Down-regulation
CAMK_CAMKL_AMPK_PRKAA2_ST	O14920	IKBKB	P54646	PRKAA2	S692	Q690E	690	Missense	proximal	-2	no	50.831	51.228	EPSD	TCGA;COSMIC	46.832	Up-regulation
CAMK_CAMKL_AMPK_PRKAA2_ST	O14920	IKBKB	P54646	PRKAA2	S692	S689C	689	Missense	distal	-3	no	50.831	45.084	EPSD	TCGA;COSMIC	46.832	Loss
CAMK_CAMKL_AMPK_PRKAA2_ST	O14920	IKBKB	P54646	PRKAA2	S692	A694T	694	Missense	proximal	2	no	50.831	47.124	EPSD	TCGA	46.832	Down-regulation
CAMK_CAMKL_AMPK_PRKAA2_ST	O14920	IKBKB	P54646	PRKAA2	T693	Q690E	690	Missense	distal	-3	no	55.094	55.536	EPSD	TCGA;COSMIC	46.832	Up-regulation
CAMK_CAMKL_AMPK_PRKAA2_ST	O14920	IKBKB	P54646	PRKAA2	T693	S689C	689	Missense	distal	-4	no	55.094	54.063	EPSD	TCGA;COSMIC	46.832	Down-regulation
CAMK_CAMKL_AMPK_PRKAA2_ST	O14920	IKBKB	P54646	PRKAA2	T693	A694T	694	Missense	proximal	1	no	55.094	55.108	EPSD	TCGA	46.832	Up-regulation
CAMK_CAMKL_AMPK_PRKAA2_ST	O14920	IKBKB	P54646	PRKAA2	S697	Q690E	690	Missense	distal	-7	no	49.686	49.942	EPSD	TCGA;COSMIC	46.832	Up-regulation
CAMK_CAMKL_AMPK_PRKAA2_ST	O14920	IKBKB	P54646	PRKAA2	S697	K703N	703	Missense	distal	6	no	49.686	50.547	EPSD	TCGA	46.832	Up-regulation
CAMK_CAMKL_AMPK_PRKAA2_ST	O14920	IKBKB	P54646	PRKAA2	S697	K704N	704	Missense	distal	7	no	49.686	50.055	EPSD	TCGA;COSMIC	46.832	Up-regulation
CAMK_CAMKL_AMPK_PRKAA2_ST	O14920	IKBKB	P54646	PRKAA2	S697	A694T	694	Missense	distal	-3	no	49.686	52.630	EPSD	TCGA	46.832	Up-regulation
CAMK_CAMKL_AMPK_PRKAA2_ST	P05549	TFAP2A	P54646	PRKAA2	S119	R124C	124	Missense	distal	5	no	47.541	47.274	EPSD	TCGA;COSMIC	46.832	Down-regulation
CAMK_CAMKL_AMPK_PRKAA2_ST	P05549	TFAP2A	P54646	PRKAA2	S119	Q117L	117	Missense	proximal	-2	no	47.541	50.319	EPSD	TCGA;COSMIC	46.832	Up-regulation
CAMK_CAMKL_AMPK_PRKAA2_ST	P05549	TFAP2A	P54646	PRKAA2	S187	S191F	191	Missense	distal	4	no	56.740	60.257	EPSD	TCGA;COSMIC	46.832	Up-regulation
CAMK_CAMKL_AMPK_PRKAA2_ST	P05549	TFAP2A	P54646	PRKAA2	S187	S191C	191	Missense	distal	4	no	56.740	39.445	EPSD	TCGA;COSMIC	46.832	Loss
CAMK_CAMKL_AMPK_PRKAA2_ST	P05549	TFAP2A	P54646	PRKAA2	S187	S181F	181	Missense	distal	-6	no	56.740	55.412	EPSD	TCGA;COSMIC	46.832	Down-regulation
CAMK_CAMKL_AMPK_PRKAA2_ST	P05549	TFAP2A	P54646	PRKAA2	S191	S191F	191	Missense	central	0	yes	49.438	0.000	EPSD	TCGA;COSMIC	46.832	Loss
CAMK_CAMKL_AMPK_PRKAA2_ST	P05549	TFAP2A	P54646	PRKAA2	S191	S191C	191	Missense	central	0	yes	49.438	0.000	EPSD	TCGA;COSMIC	46.832	Loss
CAMK_CAMKL_AMPK_PRKAA2_ST	P05549	TFAP2A	P54646	PRKAA2	S219	T224N	224	Missense	distal	5	no	67.563	67.818	PhosphoSitePlus	TCGA;COSMIC	46.832	Up-regulation
CAMK_CAMKL_AMPK_PRKAA2_ST	P05549	TFAP2A	P54646	PRKAA2	S239	S239L	239	Missense	central	0	yes	50.389	0.000	EPSD	TCGA;COSMIC	46.832	Loss
CAMK_CAMKL_AMPK_PRKAA2_ST	P05549	TFAP2A	P54646	PRKAA2	S239	E242K	242	Missense	distal	3	no	50.389	49.547	EPSD	TCGA;COSMIC	46.832	Down-regulation
CAMK_CAMKL_AMPK_PRKAA2_ST	P05549	TFAP2A	P54646	PRKAA2	S326	E330V	330	Missense	distal	4	no	44.538	54.951	EPSD	TCGA;COSMIC	46.832	Gain
AGC_NDR_NDR_STK38L_ST	O60285	NUAK1	Q9Y2H1	STK38L	T211	F208C	208	Missense	distal	-3	no	8.221	8.083	PhosphoSitePlus	TCGA;ICGC;COSMIC	2.379	Down-regulation
AGC_NDR_NDR_STK38L_ST	O60285	NUAK1	Q9Y2H1	STK38L	T211	P216S	216	Missense	distal	5	no	8.221	7.647	PhosphoSitePlus	TCGA;ICGC;COSMIC	2.379	Down-regulation
AGC_NDR_NDR_STK38L_ST	O60285	NUAK1	Q9Y2H1	STK38L	T211	T211M	211	Missense	central	0	yes	8.221	0.000	PhosphoSitePlus	TCGA;ICGC;COSMIC	2.379	Loss
AGC_NDR_NDR_STK38L_ST	O60285	NUAK1	Q9Y2H1	STK38L	T211	K207R	207	Missense	distal	-4	no	8.221	8.134	PhosphoSitePlus	TCGA;ICGC;COSMIC	2.379	Down-regulation
AGC_NDR_NDR_STK38L_ST	O60285	NUAK1	Q9Y2H1	STK38L	T211	K207T	207	Missense	distal	-4	no	8.221	8.053	PhosphoSitePlus	TCGA;ICGC;COSMIC	2.379	Down-regulation
AGC_NDR_NDR_STK38L_ST	O60285	NUAK1	Q9Y2H1	STK38L	T356	E363Q	363	Missense	distal	7	no	2.373	2.383	EPSD	TCGA;ICGC;COSMIC	2.379	Gain
AGC_NDR_NDR_STK38L_ST	O60285	NUAK1	Q9Y2H1	STK38L	T356	K350N	350	Missense	distal	-6	no	2.373	2.417	EPSD	TCGA;ICGC;COSMIC	2.379	Gain
AGC_NDR_NDR_STK38L_ST	O60285	NUAK1	Q9Y2H1	STK38L	S390	K391N	391	Missense	proximal	1	no	2.052	2.397	EPSD	TCGA;ICGC;COSMIC	2.379	Gain
AGC_NDR_NDR_STK38L_ST	O60285	NUAK1	Q9Y2H1	STK38L	S444	P443S	443	Missense	proximal	-1	no	2.435	2.645	EPSD	TCGA;ICGC;COSMIC	2.379	Up-regulation
AGC_NDR_NDR_STK38L_ST	O60285	NUAK1	Q9Y2H1	STK38L	S444	P451L	451	Missense	distal	7	no	2.435	2.417	EPSD	TCGA;ICGC;COSMIC	2.379	Down-regulation
AGC_NDR_NDR_STK38L_ST	O60285	NUAK1	Q9Y2H1	STK38L	S570	D574N	574	Missense	distal	4	no	2.117	2.444	EPSD	TCGA;ICGC;COSMIC	2.379	Gain
AGC_NDR_NDR_STK38L_ST	O60285	NUAK1	Q9Y2H1	STK38L	S636	R631W	631	Missense	distal	-5	no	2.432	1.638	EPSD	TCGA;ICGC;COSMIC	2.379	Loss
AGC_NDR_NDR_STK38L_ST	O60285	NUAK1	Q9Y2H1	STK38L	S636	M643I	643	Missense	distal	7	no	2.432	2.400	EPSD	TCGA;ICGC;COSMIC	2.379	Down-regulation
AGC_NDR_NDR_STK38L_ST	O60285	NUAK1	Q9Y2H1	STK38L	S636	R631Q	631	Missense	distal	-5	no	2.432	1.679	EPSD	TCGA;ICGC;COSMIC	2.379	Loss
AGC_NDR_NDR_STK38L_ST	O60285	NUAK1	Q9Y2H1	STK38L	S636	D642N	642	Missense	distal	6	no	2.432	2.198	EPSD	TCGA;ICGC;COSMIC	2.379	Loss
AGC_NDR_NDR_STK38L_ST	Q96QF0	RAB3IP	Q9Y2H1	STK38L	T141	D145N	145	Missense	distal	4	no	2.261	2.587	EPSD	TCGA;ICGC;COSMIC	2.379	Gain
AGC_NDR_NDR_STK38L_ST	Q96QF0	RAB3IP	Q9Y2H1	STK38L	S154	R160H	160	Missense	distal	6	no	3.223	3.169	EPSD	TCGA;COSMIC;GDSC	2.379	Down-regulation
AGC_NDR_NDR_STK38L_ST	Q96QF0	RAB3IP	Q9Y2H1	STK38L	S154	R160C	160	Missense	distal	6	no	3.223	3.159	EPSD	TCGA;ICGC;COSMIC	2.379	Down-regulation
AGC_NDR_NDR_STK38L_ST	Q96QF0	RAB3IP	Q9Y2H1	STK38L	T257	E251Q	251	Missense	distal	-6	no	2.497	2.498	EPSD	TCGA;COSMIC	2.379	Up-regulation
AGC_NDR_NDR_STK38L_ST	Q96QF0	RAB3IP	Q9Y2H1	STK38L	T257	P264T	264	Missense	distal	7	no	2.497	2.432	EPSD	TCGA;COSMIC	2.379	Down-regulation
AGC_NDR_NDR_STK38L_ST	Q96QF0	RAB3IP	Q9Y2H1	STK38L	T257	T257I	257	Missense	central	0	yes	2.497	0.000	EPSD	TCGA	2.379	Loss
AGC_NDR_NDR_STK38L_ST	Q96QF0	RAB3IP	Q9Y2H1	STK38L	T257	V252L	252	Missense	distal	-5	no	2.497	2.376	EPSD	TCGA	2.379	Loss
AGC_NDR_NDR_STK38L_ST	Q96QF0	RAB3IP	Q9Y2H1	STK38L	T257	K256N	256	Missense	proximal	-1	no	2.497	2.588	EPSD	TCGA	2.379	Up-regulation
AGC_NDR_NDR_STK38L_ST	Q96QF0	RAB3IP	Q9Y2H1	STK38L	S266	T268M	268	Missense	proximal	2	no	2.583	2.656	EPSD	TCGA;COSMIC	2.379	Up-regulation
AGC_NDR_NDR_STK38L_ST	Q96QF0	RAB3IP	Q9Y2H1	STK38L	S266	P264T	264	Missense	proximal	-2	no	2.583	2.525	EPSD	TCGA;COSMIC	2.379	Down-regulation
AGC_NDR_NDR_STK38L_ST	Q96QF0	RAB3IP	Q9Y2H1	STK38L	S266	P267S	267	Missense	proximal	1	no	2.583	3.199	EPSD	TCGA;COSMIC	2.379	Up-regulation
AGC_NDR_NDR_STK38L_ST	Q96QF0	RAB3IP	Q9Y2H1	STK38L	S266	P267L	267	Missense	proximal	1	no	2.583	2.699	EPSD	TCGA;COSMIC	2.379	Up-regulation
AGC_NDR_NDR_STK38L_ST	Q96QF0	RAB3IP	Q9Y2H1	STK38L	S266	P273S	273	Missense	distal	7	no	2.583	2.524	EPSD	TCGA	2.379	Down-regulation
AGC_NDR_NDR_STK38L_ST	Q96QF0	RAB3IP	Q9Y2H1	STK38L	S288	G295D	295	Missense	distal	7	no	8.086	8.073	PhosphoSitePlus	TCGA;COSMIC;GDSC	2.379	Down-regulation
AGC_NDR_NDR_STK38L_ST	Q96QF0	RAB3IP	Q9Y2H1	STK38L	S288	R285I	285	Missense	distal	-3	no	8.086	7.952	PhosphoSitePlus	TCGA;COSMIC	2.379	Down-regulation
AGC_NDR_NDR_STK38L_ST	P46937	YAP1	Q9Y2H1	STK38L	S94	F95C	95	Missense	proximal	1	no	4.182	4.187	EPSD	TCGA;ICGC	2.379	Up-regulation
AGC_NDR_NDR_STK38L_ST	P46937	YAP1	Q9Y2H1	STK38L	S105	R106Q	106	Missense	proximal	1	no	3.816	3.751	EPSD	TCGA;ICGC;COSMIC;CCLE	2.379	Down-regulation
AGC_NDR_NDR_STK38L_ST	P46937	YAP1	Q9Y2H1	STK38L	S105	S109N	109	Missense	distal	4	no	3.816	3.074	EPSD	TCGA;ICGC;COSMIC	2.379	Down-regulation
AGC_NDR_NDR_STK38L_ST	P46937	YAP1	Q9Y2H1	STK38L	S109	R106Q	106	Missense	distal	-3	no	2.488	2.344	EPSD	TCGA;ICGC;COSMIC;CCLE	2.379	Loss
AGC_NDR_NDR_STK38L_ST	P46937	YAP1	Q9Y2H1	STK38L	S109	S109N	109	Missense	central	0	yes	2.488	0.000	EPSD	TCGA;ICGC;COSMIC	2.379	Loss
AGC_NDR_NDR_STK38L_ST	P46937	YAP1	Q9Y2H1	STK38L	S127	Q121H	121	Missense	distal	-6	no	9.436	9.452	PhosphoSitePlus	TCGA;ICGC;COSMIC	2.379	Up-regulation
AGC_NDR_NDR_STK38L_ST	P46937	YAP1	Q9Y2H1	STK38L	S127	P129S	129	Missense	proximal	2	no	9.436	9.491	PhosphoSitePlus	TCGA;ICGC;COSMIC	2.379	Up-regulation
AGC_NDR_NDR_STK38L_ST	P46937	YAP1	Q9Y2H1	STK38L	S127	R124P	124	Missense	distal	-3	no	9.436	9.293	PhosphoSitePlus	TCGA;ICGC;COSMIC	2.379	Down-regulation
AGC_NDR_NDR_STK38L_ST	P46937	YAP1	Q9Y2H1	STK38L	S127	R124Q	124	Missense	distal	-3	no	9.436	9.292	PhosphoSitePlus	TCGA;ICGC;COSMIC	2.379	Down-regulation
AGC_NDR_NDR_STK38L_ST	P46937	YAP1	Q9Y2H1	STK38L	T154	T154A	154	Missense	central	0	yes	2.447	0.000	EPSD	TCGA;ICGC;COSMIC	2.379	Loss
AGC_NDR_NDR_STK38L_ST	P46937	YAP1	Q9Y2H1	STK38L	T154	Q158H	158	Missense	distal	4	no	2.447	2.864	EPSD	TCGA;ICGC;COSMIC	2.379	Up-regulation
AGC_NDR_NDR_STK38L_ST	P46937	YAP1	Q9Y2H1	STK38L	S163	Q158H	158	Missense	distal	-5	no	2.081	3.374	EPSD	TCGA;ICGC;COSMIC	2.379	Gain
AGC_NDR_NDR_STK38L_ST	P46937	YAP1	Q9Y2H1	STK38L	S336	P341A	341	Missense	distal	5	no	3.535	3.059	EPSD	TCGA;ICGC;COSMIC	2.379	Down-regulation
AGC_NDR_NDR_STK38L_ST	P46937	YAP1	Q9Y2H1	STK38L	S336	I333N	333	Missense	distal	-3	no	3.535	3.525	EPSD	TCGA;ICGC;COSMIC	2.379	Down-regulation
AGC_NDR_NDR_STK38L_ST	P46937	YAP1	Q9Y2H1	STK38L	S336	N339H	339	Missense	distal	3	no	3.535	4.032	EPSD	TCGA;ICGC;COSMIC	2.379	Up-regulation
AGC_NDR_NDR_STK38L_ST	P46937	YAP1	Q9Y2H1	STK38L	T378	D383E	383	Missense	distal	5	no	3.593	3.550	EPSD	TCGA;ICGC;COSMIC	2.379	Down-regulation
AGC_NDR_NDR_STK38L_ST	P46937	YAP1	Q9Y2H1	STK38L	T379	D383E	383	Missense	distal	4	no	2.065	2.598	EPSD	TCGA;ICGC;COSMIC	2.379	Gain
AGC_NDR_NDR_STK38L_ST	P46937	YAP1	Q9Y2H1	STK38L	S397	E396D	396	Missense	proximal	-1	no	7.869	8.000	EPSD	TCGA;ICGC;COSMIC	2.379	Up-regulation
AGC_NDR_NDR_STK38L_ST	P46937	YAP1	Q9Y2H1	STK38L	S499	L501F	501	Missense	proximal	2	no	2.920	3.017	EPSD	TCGA;ICGC;COSMIC	2.379	Up-regulation
AGC_NDR_NDR_STK38L_ST	Q9Y2H1	STK38L	Q9Y2H1	STK38L	S282	A280V	280	Missense	proximal	-2	no	7.554	7.508	PhosphoSitePlus	TCGA;COSMIC	2.379	Down-regulation
AGC_NDR_NDR_STK38L_ST	Q9Y2H1	STK38L	Q9Y2H1	STK38L	T450	S454F	454	Missense	distal	4	no	3.445	2.597	EPSD	TCGA;ICGC	2.379	Down-regulation
AGC_NDR_NDR_STK38L_ST	Q9Y2H1	STK38L	Q9Y2H1	STK38L	T450	K444T	444	Missense	distal	-6	no	3.445	3.422	EPSD	TCGA;ICGC	2.379	Down-regulation
CK1_CK1_CK1-D_CSNK1E_ST	O15055	PER2	P49674	CSNK1E	T43	H41R	41	Missense	proximal	-2	no	27.802	25.627	EPSD	TCGA;ICGC;COSMIC	22.404	Down-regulation
CK1_CK1_CK1-D_CSNK1E_ST	O15055	PER2	P49674	CSNK1E	S56	R51W	51	Missense	distal	-5	no	22.846	22.035	EPSD	TCGA;ICGC;COSMIC	22.404	Loss
CK1_CK1_CK1-D_CSNK1E_ST	O15055	PER2	P49674	CSNK1E	S56	K63N	63	Missense	distal	7	no	22.846	22.862	EPSD	TCGA;ICGC	22.404	Up-regulation
CK1_CK1_CK1-D_CSNK1E_ST	O15055	PER2	P49674	CSNK1E	S56	R51P	51	Missense	distal	-5	no	22.846	23.358	EPSD	TCGA;ICGC;COSMIC	22.404	Up-regulation
CK1_CK1_CK1-D_CSNK1E_ST	O15055	PER2	P49674	CSNK1E	S56	D60N	60	Missense	distal	4	no	22.846	22.880	EPSD	TCGA;ICGC;COSMIC	22.404	Up-regulation
CK1_CK1_CK1-D_CSNK1E_ST	O15055	PER2	P49674	CSNK1E	S810	V817M	817	Missense	distal	7	no	25.780	25.512	EPSD	TCGA;ICGC;COSMIC;GDSC;CCLE	22.404	Down-regulation
CK1_CK1_CK1-D_CSNK1E_ST	O15055	PER2	P49674	CSNK1E	S810	S813Y	813	Missense	distal	3	no	25.780	15.909	EPSD	TCGA;ICGC	22.404	Loss
CK1_CK1_CK1-D_CSNK1E_ST	O15055	PER2	P49674	CSNK1E	S971	A964T	964	Missense	distal	-7	no	24.632	24.636	EPSD	TCGA;ICGC	22.404	Up-regulation
CK1_CK1_CK1-D_CSNK1E_ST	O15055	PER2	P49674	CSNK1E	S971	A972S	972	Missense	proximal	1	no	24.632	24.921	EPSD	TCGA;ICGC;COSMIC	22.404	Up-regulation
CK1_CK1_CK1-D_CSNK1E_ST	O15055	PER2	P49674	CSNK1E	S971	P978S	978	Missense	distal	7	no	24.632	24.428	EPSD	TCGA;ICGC;COSMIC	22.404	Down-regulation
CK1_CK1_CK1-D_CSNK1E_ST	O15055	PER2	P49674	CSNK1E	S977	P979T	979	Missense	proximal	2	no	21.713	24.123	EPSD	TCGA;ICGC;COSMIC	22.404	Gain
CK1_CK1_CK1-D_CSNK1E_ST	O15055	PER2	P49674	CSNK1E	T1013	A1016T	1016	Missense	distal	3	no	27.830	28.852	EPSD	TCGA;ICGC;COSMIC	22.404	Up-regulation
CK1_CK1_CK1-D_CSNK1E_ST	O15055	PER2	P49674	CSNK1E	T1013	V1018L	1018	Missense	distal	5	no	27.830	27.696	EPSD	TCGA;ICGC;COSMIC	22.404	Down-regulation
CK1_CK1_CK1-D_CSNK1E_ST	O15055	PER2	P49674	CSNK1E	T1013	A1020V	1020	Missense	distal	7	no	27.830	28.286	EPSD	TCGA;ICGC;COSMIC	22.404	Up-regulation
CK1_CK1_CK1-D_CSNK1E_ST	O15055	PER2	P49674	CSNK1E	T1015	A1016T	1016	Missense	proximal	1	no	27.017	26.694	EPSD	TCGA;ICGC;COSMIC	22.404	Down-regulation
CK1_CK1_CK1-D_CSNK1E_ST	O15055	PER2	P49674	CSNK1E	T1015	V1018L	1018	Missense	distal	3	no	27.017	28.800	EPSD	TCGA;ICGC;COSMIC	22.404	Up-regulation
CK1_CK1_CK1-D_CSNK1E_ST	O15055	PER2	P49674	CSNK1E	T1015	A1020V	1020	Missense	distal	5	no	27.017	27.935	EPSD	TCGA;ICGC;COSMIC	22.404	Up-regulation
CK1_CK1_CK1-D_CSNK1E_ST	Q92997	DVL3	P49674	CSNK1E	T15	L18F	18	Missense	distal	3	no	19.702	23.977	EPSD	TCGA;ICGC;COSMIC	22.404	Gain
CK1_CK1_CK1-D_CSNK1E_ST	Q92997	DVL3	P49674	CSNK1E	S125	Q126R	126	Missense	proximal	1	no	29.683	30.071	EPSD	TCGA;ICGC	22.404	Up-regulation
CK1_CK1_CK1-D_CSNK1E_ST	Q92997	DVL3	P49674	CSNK1E	T178	G172S	172	Missense	distal	-6	no	27.369	28.454	EPSD	TCGA;ICGC;COSMIC	22.404	Up-regulation
CK1_CK1_CK1-D_CSNK1E_ST	Q92997	DVL3	P49674	CSNK1E	S209	R212C	212	Missense	distal	3	no	36.405	29.357	EPSD	TCGA;ICGC;COSMIC	22.404	Down-regulation
CK1_CK1_CK1-D_CSNK1E_ST	Q92997	DVL3	P49674	CSNK1E	S234	S227F	227	Missense	distal	-7	no	26.611	26.607	EPSD	TCGA;ICGC;COSMIC	22.404	Down-regulation
CK1_CK1_CK1-D_CSNK1E_ST	Q92997	DVL3	P49674	CSNK1E	S234	R231Q	231	Missense	distal	-3	no	26.611	26.451	EPSD	TCGA;ICGC;COSMIC	22.404	Down-regulation
CK1_CK1_CK1-D_CSNK1E_ST	Q92997	DVL3	P49674	CSNK1E	S234	R228Q	228	Missense	distal	-6	no	26.611	27.068	EPSD	TCGA;ICGC	22.404	Up-regulation
CK1_CK1_CK1-D_CSNK1E_ST	Q92997	DVL3	P49674	CSNK1E	S234	T239M	239	Missense	distal	5	no	26.611	26.867	EPSD	TCGA;ICGC;COSMIC	22.404	Up-regulation
CK1_CK1_CK1-D_CSNK1E_ST	Q92997	DVL3	P49674	CSNK1E	S237	R231Q	231	Missense	distal	-6	no	25.798	26.254	EPSD	TCGA;ICGC;COSMIC	22.404	Up-regulation
CK1_CK1_CK1-D_CSNK1E_ST	Q92997	DVL3	P49674	CSNK1E	S237	T239M	239	Missense	proximal	2	no	25.798	25.679	EPSD	TCGA;ICGC;COSMIC	22.404	Down-regulation
CK1_CK1_CK1-D_CSNK1E_ST	Q92997	DVL3	P49674	CSNK1E	S268	D273Y	273	Missense	distal	5	no	23.063	24.625	EPSD	TCGA;ICGC;COSMIC	22.404	Up-regulation
CK1_CK1_CK1-D_CSNK1E_ST	Q92997	DVL3	P49674	CSNK1E	S268	G261S	261	Missense	distal	-7	no	23.063	23.064	EPSD	TCGA;ICGC;COSMIC	22.404	Up-regulation
CK1_CK1_CK1-D_CSNK1E_ST	Q92997	DVL3	P49674	CSNK1E	S516	P523S	523	Missense	distal	7	no	27.900	27.695	EPSD	TCGA;COSMIC	22.404	Down-regulation
CK1_CK1_CK1-D_CSNK1E_ST	Q92997	DVL3	P49674	CSNK1E	S516	D510N	510	Missense	distal	-6	no	27.900	28.369	EPSD	TCGA;COSMIC	22.404	Up-regulation
CK1_CK1_CK1-D_CSNK1E_ST	Q92997	DVL3	P49674	CSNK1E	S564	G562V	562	Missense	proximal	-2	no	24.646	25.720	EPSD	TCGA;COSMIC	22.404	Up-regulation
CK1_CK1_CK1-D_CSNK1E_ST	Q92997	DVL3	P49674	CSNK1E	S567	G562V	562	Missense	distal	-5	no	37.739	37.506	EPSD	TCGA;COSMIC	22.404	Down-regulation
CK1_CK1_CK1-D_CSNK1E_ST	Q92997	DVL3	P49674	CSNK1E	S575	G577V	577	Missense	proximal	2	no	23.230	25.017	EPSD	TCGA;COSMIC	22.404	Up-regulation
CK1_CK1_CK1-D_CSNK1E_ST	Q92997	DVL3	P49674	CSNK1E	S575	G582S	582	Missense	distal	7	no	23.230	23.026	EPSD	TCGA;COSMIC	22.404	Down-regulation
CK1_CK1_CK1-D_CSNK1E_ST	Q92997	DVL3	P49674	CSNK1E	S575	S576G	576	Missense	proximal	1	no	23.230	22.251	EPSD	TCGA;COSMIC	22.404	Loss
CK1_CK1_CK1-D_CSNK1E_ST	Q92997	DVL3	P49674	CSNK1E	S578	G577V	577	Missense	proximal	-1	no	23.547	20.734	EPSD	TCGA;COSMIC	22.404	Loss
CK1_CK1_CK1-D_CSNK1E_ST	Q92997	DVL3	P49674	CSNK1E	S578	G582S	582	Missense	distal	4	no	23.547	23.438	EPSD	TCGA;COSMIC	22.404	Down-regulation
CK1_CK1_CK1-D_CSNK1E_ST	Q92997	DVL3	P49674	CSNK1E	S578	S583G	583	Missense	distal	5	no	23.547	24.994	EPSD	TCGA;COSMIC	22.404	Up-regulation
CK1_CK1_CK1-D_CSNK1E_ST	Q92997	DVL3	P49674	CSNK1E	S578	S576G	576	Missense	proximal	-2	no	23.547	21.346	EPSD	TCGA;COSMIC	22.404	Loss
CK1_CK1_CK1-D_CSNK1E_ST	Q92997	DVL3	P49674	CSNK1E	S639	R645C	645	Missense	distal	6	no	23.548	18.210	EPSD;PhosphoSitePlus	TCGA;COSMIC	22.404	Loss
CK1_CK1_CK1-D_CSNK1E_ST	Q92997	DVL3	P49674	CSNK1E	S643	R645C	645	Missense	proximal	2	no	22.651	23.632	EPSD;PhosphoSitePlus	TCGA;COSMIC	22.404	Up-regulation
CK1_CK1_CK1-D_CSNK1E_ST	Q92997	DVL3	P49674	CSNK1E	S697	E693K	693	Missense	distal	-4	no	30.413	24.847	EPSD	TCGA;COSMIC	22.404	Down-regulation
CK1_CK1_CK1-D_CSNK1E_ST	Q92997	DVL3	P49674	CSNK1E	S697	P692L	692	Missense	distal	-5	no	30.413	29.770	EPSD	TCGA;ICGC;COSMIC	22.404	Down-regulation
CK1_CK1_CK1-D_CSNK1E_ST	O95863	SNAI1	P49674	CSNK1E	S104	P110S	110	Missense	distal	6	no	33.743	33.105	PhosphoSitePlus;EPSD	TCGA;ICGC;COSMIC	22.404	Down-regulation
CK1_CK1_CK1-D_CSNK1E_ST	O95863	SNAI1	P49674	CSNK1E	S107	P110S	110	Missense	distal	3	no	39.045	40.027	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	22.404	Up-regulation
CK1_CK1_CK1-D_CSNK1E_ST	O95863	SNAI1	P49674	CSNK1E	S107	S114F	114	Missense	distal	7	no	39.045	39.778	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	22.404	Up-regulation
CK1_CK1_CK1-D_CSNK1E_ST	Q8TD43	TRPM4	P49674	CSNK1E	S104	W110L	110	Missense	distal	6	no	23.239	24.862	EPSD	TCGA;ICGC;COSMIC	22.404	Up-regulation
CK1_CK1_CK1-D_CSNK1E_ST	Q8TD43	TRPM4	P49674	CSNK1E	S104	V102A	102	Missense	proximal	-2	no	23.239	25.225	EPSD	TCGA;ICGC;COSMIC	22.404	Up-regulation
CK1_CK1_CK1-D_CSNK1E_ST	Q8TD43	TRPM4	P49674	CSNK1E	S104	V102I	102	Missense	proximal	-2	no	23.239	23.578	EPSD	TCGA;ICGC;COSMIC	22.404	Up-regulation
CK1_CK1_CK1-D_CSNK1E_ST	Q8TD43	TRPM4	P49674	CSNK1E	S104	W110R	110	Missense	distal	6	no	23.239	28.195	EPSD	TCGA;ICGC	22.404	Up-regulation
CK1_CK1_CK1-D_CSNK1E_ST	Q8TD43	TRPM4	P49674	CSNK1E	S104	R108H	108	Missense	distal	4	no	23.239	23.200	EPSD	TCGA;ICGC;COSMIC;GDSC	22.404	Down-regulation
CK1_CK1_CK1-D_CSNK1E_ST	Q8TD43	TRPM4	P49674	CSNK1E	S255	R248H	248	Missense	distal	-7	no	22.910	22.909	EPSD	TCGA;ICGC;COSMIC	22.404	Down-regulation
CK1_CK1_CK1-D_CSNK1E_ST	Q9Y6Q9	NCOA3	P49674	CSNK1E	S13	L11M	11	Missense	proximal	-2	no	19.626	22.815	EPSD	TCGA;ICGC;COSMIC	22.404	Gain
CK1_CK1_CK1-D_CSNK1E_ST	Q9Y6Q9	NCOA3	P49674	CSNK1E	S102	T103A	103	Missense	proximal	1	no	34.349	34.672	PhosphoSitePlus	TCGA;ICGC;COSMIC	22.404	Up-regulation
CK1_CK1_CK1-D_CSNK1E_ST	Q9Y6Q9	NCOA3	P49674	CSNK1E	S102	G106R	106	Missense	distal	4	no	34.349	34.412	PhosphoSitePlus	TCGA;ICGC;COSMIC	22.404	Up-regulation
CK1_CK1_CK1-D_CSNK1E_ST	Q9Y6Q9	NCOA3	P49674	CSNK1E	S102	D99N	99	Missense	distal	-3	no	34.349	31.911	PhosphoSitePlus	TCGA;ICGC;COSMIC	22.404	Down-regulation
CK1_CK1_CK1-D_CSNK1E_ST	Q9Y6Q9	NCOA3	P49674	CSNK1E	S214	A213G	213	Missense	proximal	-1	no	37.141	32.286	EPSD	TCGA;ICGC;COSMIC	22.404	Down-regulation
CK1_CK1_CK1-D_CSNK1E_ST	Q9Y6Q9	NCOA3	P49674	CSNK1E	S214	A213V	213	Missense	proximal	-1	no	37.141	29.473	EPSD	TCGA;ICGC;COSMIC	22.404	Down-regulation
CK1_CK1_CK1-D_CSNK1E_ST	Q9Y6Q9	NCOA3	P49674	CSNK1E	S287	G292V	292	Missense	distal	5	no	25.354	25.327	EPSD	TCGA;ICGC;COSMIC	22.404	Down-regulation
CK1_CK1_CK1-D_CSNK1E_ST	Q9Y6Q9	NCOA3	P49674	CSNK1E	S414	P412A	412	Missense	proximal	-2	no	21.894	24.082	EPSD	TCGA;ICGC;COSMIC	22.404	Gain
CK1_CK1_CK1-D_CSNK1E_ST	Q9Y6Q9	NCOA3	P49674	CSNK1E	T425	S429R	429	Missense	distal	4	no	25.196	25.369	EPSD	TCGA;ICGC;COSMIC	22.404	Up-regulation
CK1_CK1_CK1-D_CSNK1E_ST	Q9Y6Q9	NCOA3	P49674	CSNK1E	S652	K647R	647	Missense	distal	-5	no	24.559	24.745	EPSD	TCGA;ICGC;COSMIC	22.404	Up-regulation
CK1_CK1_CK1-D_CSNK1E_ST	Q9Y6Q9	NCOA3	P49674	CSNK1E	S662	S662C	662	Missense	central	0	yes	24.334	0.000	EPSD	TCGA;COSMIC	22.404	Loss
CK1_CK1_CK1-D_CSNK1E_ST	Q9Y6Q9	NCOA3	P49674	CSNK1E	S662	S669C	669	Missense	distal	7	no	24.334	24.697	EPSD	TCGA;ICGC;COSMIC	22.404	Up-regulation
CK1_CK1_CK1-D_CSNK1E_ST	Q9Y6Q9	NCOA3	P49674	CSNK1E	S712	D709Y	709	Missense	distal	-3	no	23.305	18.902	EPSD	TCGA;COSMIC	22.404	Loss
CK1_CK1_CK1-D_CSNK1E_ST	Q9Y6Q9	NCOA3	P49674	CSNK1E	S712	S715F	715	Missense	distal	3	no	23.305	20.777	EPSD	TCGA;COSMIC	22.404	Loss
CK1_CK1_CK1-D_CSNK1E_ST	Q9Y6Q9	NCOA3	P49674	CSNK1E	S715	D709Y	709	Missense	distal	-6	no	25.096	25.013	EPSD	TCGA;COSMIC	22.404	Down-regulation
CK1_CK1_CK1-D_CSNK1E_ST	Q9Y6Q9	NCOA3	P49674	CSNK1E	S715	S715F	715	Missense	central	0	yes	25.096	0.000	EPSD	TCGA;COSMIC	22.404	Loss
CK1_CK1_CK1-D_CSNK1E_ST	Q9Y6Q9	NCOA3	P49674	CSNK1E	S715	V721A	721	Missense	distal	6	no	25.096	26.597	EPSD	TCGA	22.404	Up-regulation
CK1_CK1_CK1-D_CSNK1E_ST	Q9Y6Q9	NCOA3	P49674	CSNK1E	S771	I774S	774	Missense	distal	3	no	22.699	26.697	EPSD	TCGA;ICGC;COSMIC	22.404	Up-regulation
CK1_CK1_CK1-D_CSNK1E_ST	Q9Y6Q9	NCOA3	P49674	CSNK1E	S772	I774S	774	Missense	proximal	2	no	23.792	23.253	EPSD	TCGA;ICGC;COSMIC	22.404	Down-regulation
CK1_CK1_CK1-D_CSNK1E_ST	Q9Y6Q9	NCOA3	P49674	CSNK1E	S844	S841T	841	Missense	distal	-3	no	28.117	26.223	EPSD	TCGA;ICGC;COSMIC	22.404	Down-regulation
CK1_CK1_CK1-D_CSNK1E_ST	Q9Y6Q9	NCOA3	P49674	CSNK1E	S844	R849C	849	Missense	distal	5	no	28.117	27.895	EPSD	TCGA;ICGC;COSMIC	22.404	Down-regulation
CK1_CK1_CK1-D_CSNK1E_ST	Q9Y6Q9	NCOA3	P49674	CSNK1E	S844	R849H	849	Missense	distal	5	no	28.117	27.543	EPSD	TCGA;ICGC	22.404	Down-regulation
CK1_CK1_CK1-D_CSNK1E_ST	Q9Y6Q9	NCOA3	P49674	CSNK1E	S916	P915S	915	Missense	proximal	-1	no	24.860	25.764	EPSD	TCGA;ICGC;COSMIC	22.404	Up-regulation
CK1_CK1_CK1-D_CSNK1E_ST	Q9Y6Q9	NCOA3	P49674	CSNK1E	S917	P915S	915	Missense	proximal	-2	no	21.526	22.855	EPSD	TCGA;ICGC;COSMIC	22.404	Gain
CK1_CK1_CK1-D_CSNK1E_ST	P49674	CSNK1E	P49674	CSNK1E	T44	P47S	47	Missense	distal	3	no	33.821	34.803	EPSD	TCGA;ICGC;COSMIC	22.404	Up-regulation
CK1_CK1_CK1-D_CSNK1E_ST	P49674	CSNK1E	P49674	CSNK1E	S323	M317I	317	Missense	distal	-6	no	32.443	32.657	PhosphoSitePlus;EPSD	TCGA;ICGC;COSMIC	22.404	Up-regulation
CK1_CK1_CK1-D_CSNK1E_ST	P49674	CSNK1E	P49674	CSNK1E	T334	T334M	334	Missense	central	0	yes	36.881	0.000	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	22.404	Loss
CK1_CK1_CK1-D_CSNK1E_ST	P49674	CSNK1E	P49674	CSNK1E	T337	R342C	342	Missense	distal	5	no	34.851	34.628	EPSD;PhosphoSitePlus	TCGA	22.404	Down-regulation
CK1_CK1_CK1-D_CSNK1E_ST	P49674	CSNK1E	P49674	CSNK1E	T337	T334M	334	Missense	distal	-3	no	34.851	35.733	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	22.404	Up-regulation
CK1_CK1_CK1-D_CSNK1E_ST	P49674	CSNK1E	P49674	CSNK1E	T351	P358T	358	Missense	distal	7	no	26.172	26.519	EPSD	TCGA;ICGC;COSMIC	22.404	Up-regulation
CK1_CK1_CK1-D_CSNK1E_ST	P49674	CSNK1E	P49674	CSNK1E	S354	P358T	358	Missense	distal	4	no	23.316	23.354	EPSD	TCGA;ICGC;COSMIC	22.404	Up-regulation
CK1_CK1_CK1-D_CSNK1E_ST	P49674	CSNK1E	P49674	CSNK1E	S368	S368L	368	Missense	central	0	yes	35.358	0.000	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC;GDSC;CCLE	22.404	Loss
CK1_CK1_CK1-D_CSNK1E_ST	P49674	CSNK1E	P49674	CSNK1E	S368	A366V	366	Missense	proximal	-2	no	35.358	33.372	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC;CCLE	22.404	Down-regulation
CK1_CK1_CK1-D_CSNK1E_ST	P49674	CSNK1E	P49674	CSNK1E	S368	S368P	368	Missense	central	0	yes	35.358	0.000	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	22.404	Loss
CK1_CK1_CK1-D_CSNK1E_ST	P49674	CSNK1E	P49674	CSNK1E	S368	E373D	373	Missense	distal	5	no	35.358	35.227	EPSD;PhosphoSitePlus	TCGA	22.404	Down-regulation
CK1_CK1_CK1-D_CSNK1E_ST	P49674	CSNK1E	P49674	CSNK1E	S390	S389F	389	Missense	proximal	-1	no	23.913	16.207	EPSD	TCGA;ICGC;COSMIC	22.404	Loss
CK1_CK1_CK1-D_CSNK1E_ST	P49674	CSNK1E	P49674	CSNK1E	S390	R396W	396	Missense	distal	6	no	23.913	18.957	EPSD	TCGA;ICGC	22.404	Loss
CK1_CK1_CK1-D_CSNK1E_ST	P49674	CSNK1E	P49674	CSNK1E	S390	N387S	387	Missense	distal	-3	no	23.913	26.178	EPSD	TCGA;ICGC;COSMIC	22.404	Up-regulation
CK1_CK1_CK1-D_CSNK1E_ST	P49674	CSNK1E	P49674	CSNK1E	S405	R401Q	401	Missense	distal	-4	no	24.727	26.478	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	22.404	Up-regulation
CK1_CK1_CK1-D_CSNK1E_ST	P49674	CSNK1E	P49674	CSNK1E	S405	A404V	404	Missense	proximal	-1	no	24.727	17.059	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	22.404	Loss
CK1_CK1_CK1-D_CSNK1E_ST	P49674	CSNK1E	P49674	CSNK1E	S405	R401W	401	Missense	distal	-4	no	24.727	18.820	EPSD;PhosphoSitePlus	TCGA;ICGC	22.404	Loss
CK1_CK1_CK1-D_CSNK1E_ST	O14641	DVL2	P49674	CSNK1E	S143	P149L	149	Missense	distal	6	no	32.930	29.134	PhosphoSitePlus;EPSD	TCGA;ICGC;COSMIC	22.404	Down-regulation
CK1_CK1_CK1-D_CSNK1E_ST	O14641	DVL2	P49674	CSNK1E	S143	S141Y	141	Missense	proximal	-2	no	32.930	27.395	PhosphoSitePlus;EPSD	TCGA;ICGC;COSMIC	22.404	Down-regulation
CK1_CK1_CK1-D_CSNK1E_ST	O14641	DVL2	P49674	CSNK1E	S155	R161W	161	Missense	distal	6	no	29.945	24.989	EPSD	TCGA;ICGC;COSMIC	22.404	Down-regulation
CK1_CK1_CK1-D_CSNK1E_ST	O14641	DVL2	P49674	CSNK1E	S155	P149L	149	Missense	distal	-6	no	29.945	29.320	EPSD	TCGA;ICGC;COSMIC	22.404	Down-regulation
CK1_CK1_CK1-D_CSNK1E_ST	O14641	DVL2	P49674	CSNK1E	S158	R161W	161	Missense	distal	3	no	29.778	26.272	EPSD	TCGA;ICGC;COSMIC	22.404	Down-regulation
CK1_CK1_CK1-D_CSNK1E_ST	O14641	DVL2	P49674	CSNK1E	S158	R165H	165	Missense	distal	7	no	29.778	29.910	EPSD	TCGA;ICGC;COSMIC	22.404	Up-regulation
CK1_CK1_CK1-D_CSNK1E_ST	O14641	DVL2	P49674	CSNK1E	T224	R231C	231	Missense	distal	7	no	32.742	32.804	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	22.404	Up-regulation
CK1_CK1_CK1-D_CSNK1E_ST	O14641	DVL2	P49674	CSNK1E	T224	S218I	218	Missense	distal	-6	no	32.742	32.917	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	22.404	Up-regulation
CK1_CK1_CK1-D_CSNK1E_ST	O14641	DVL2	P49674	CSNK1E	S227	R231C	231	Missense	distal	4	no	26.666	26.670	EPSD	TCGA;ICGC;COSMIC	22.404	Up-regulation
CK1_CK1_CK1-D_CSNK1E_ST	O14641	DVL2	P49674	CSNK1E	S228	R231C	231	Missense	distal	3	no	35.464	28.416	EPSD	TCGA;ICGC;COSMIC	22.404	Down-regulation
CK1_CK1_CK1-D_CSNK1E_ST	O14641	DVL2	P49674	CSNK1E	S252	R246H	246	Missense	distal	-6	no	22.926	23.609	EPSD	TCGA;ICGC;COSMIC	22.404	Up-regulation
CK1_CK1_CK1-D_CSNK1E_ST	O14641	DVL2	P49674	CSNK1E	S252	R246C	246	Missense	distal	-6	no	22.926	22.557	EPSD	TCGA;ICGC;COSMIC	22.404	Down-regulation
CK1_CK1_CK1-D_CSNK1E_ST	O14641	DVL2	P49674	CSNK1E	S252	P245L	245	Missense	distal	-7	no	22.926	22.922	EPSD	TCGA;ICGC;COSMIC	22.404	Down-regulation
CK1_CK1_CK1-D_CSNK1E_ST	O14641	DVL2	P49674	CSNK1E	S252	D258Y	258	Missense	distal	6	no	22.926	18.886	EPSD	TCGA;ICGC	22.404	Loss
CK1_CK1_CK1-D_CSNK1E_ST	O14641	DVL2	P49674	CSNK1E	S255	D258Y	258	Missense	distal	3	no	30.144	19.487	EPSD	TCGA;ICGC	22.404	Loss
CK1_CK1_CK1-D_CSNK1E_ST	O14641	DVL2	P49674	CSNK1E	S286	N287H	287	Missense	proximal	1	no	24.069	24.094	EPSD	TCGA;ICGC;COSMIC	22.404	Up-regulation
CK1_CK1_CK1-D_CSNK1E_ST	O14641	DVL2	P49674	CSNK1E	S286	R289W	289	Missense	distal	3	no	24.069	20.563	EPSD	TCGA;ICGC;COSMIC;GDSC;CCLE	22.404	Loss
CK1_CK1_CK1-D_CSNK1E_ST	O14641	DVL2	P49674	CSNK1E	S398	S397F	397	Missense	proximal	-1	no	39.333	31.627	EPSD	TCGA;ICGC	22.404	Down-regulation
CK1_CK1_CK1-D_CSNK1E_ST	O14641	DVL2	P49674	CSNK1E	S398	S398F	398	Missense	central	0	yes	39.333	0.000	EPSD	TCGA;ICGC;COSMIC	22.404	Loss
CK1_CK1_CK1-D_CSNK1E_ST	O14641	DVL2	P49674	CSNK1E	S398	G395D	395	Missense	distal	-3	no	39.333	39.230	EPSD	TCGA;ICGC;COSMIC	22.404	Down-regulation
CK1_CK1_CK1-D_CSNK1E_ST	O14641	DVL2	P49674	CSNK1E	T401	S397F	397	Missense	distal	-4	no	27.722	22.600	EPSD	TCGA;ICGC	22.404	Down-regulation
CK1_CK1_CK1-D_CSNK1E_ST	O14641	DVL2	P49674	CSNK1E	T401	S398F	398	Missense	distal	-3	no	27.722	25.286	EPSD	TCGA;ICGC;COSMIC	22.404	Down-regulation
CK1_CK1_CK1-D_CSNK1E_ST	O14641	DVL2	P49674	CSNK1E	T401	G395D	395	Missense	distal	-6	no	27.722	27.906	EPSD	TCGA;ICGC;COSMIC	22.404	Up-regulation
CK1_CK1_CK1-D_CSNK1E_ST	O14641	DVL2	P49674	CSNK1E	S404	S397F	397	Missense	distal	-7	no	31.747	31.743	EPSD	TCGA;ICGC	22.404	Down-regulation
CK1_CK1_CK1-D_CSNK1E_ST	O14641	DVL2	P49674	CSNK1E	S404	S398F	398	Missense	distal	-6	no	31.747	30.597	EPSD	TCGA;ICGC;COSMIC	22.404	Down-regulation
CK1_CK1_CK1-D_CSNK1E_ST	O14641	DVL2	P49674	CSNK1E	S404	P409S	409	Missense	distal	5	no	31.747	31.454	EPSD	TCGA;ICGC	22.404	Down-regulation
CK1_CK1_CK1-D_CSNK1E_ST	O14641	DVL2	P49674	CSNK1E	S407	P409S	409	Missense	proximal	2	no	23.280	24.855	EPSD	TCGA;ICGC	22.404	Up-regulation
CK1_CK1_CK1-D_CSNK1E_ST	O14641	DVL2	P49674	CSNK1E	S580	S583N	583	Missense	distal	3	no	26.817	21.507	EPSD	TCGA;ICGC;COSMIC	22.404	Loss
CK1_CK1_CK1-D_CSNK1E_ST	O14641	DVL2	P49674	CSNK1E	S583	S583N	583	Missense	central	0	yes	41.730	0.000	EPSD	TCGA;ICGC;COSMIC	22.404	Loss
CK1_CK1_CK1-D_CSNK1E_ST	O14641	DVL2	P49674	CSNK1E	S614	E608K	608	Missense	distal	-6	no	20.603	22.735	EPSD	TCGA;ICGC;COSMIC	22.404	Gain
CK1_CK1_CK1-D_CSNK1E_ST	O14641	DVL2	P49674	CSNK1E	S616	E613K	613	Missense	distal	-3	no	25.336	26.425	EPSD	TCGA;ICGC;COSMIC	22.404	Up-regulation
CK1_CK1_CK1-D_CSNK1E_ST	O14641	DVL2	P49674	CSNK1E	S616	K615T	615	Missense	proximal	-1	no	25.336	26.270	EPSD	TCGA;ICGC;COSMIC	22.404	Up-regulation
CK1_CK1_CK1-D_CSNK1E_ST	O14641	DVL2	P49674	CSNK1E	S616	E623G	623	Missense	distal	7	no	25.336	25.357	EPSD	TCGA;ICGC	22.404	Up-regulation
CK1_CK1_CK1-D_CSNK1E_ST	O14641	DVL2	P49674	CSNK1E	S618	E613K	613	Missense	distal	-5	no	31.832	30.949	EPSD	TCGA;ICGC;COSMIC	22.404	Down-regulation
CK1_CK1_CK1-D_CSNK1E_ST	O14641	DVL2	P49674	CSNK1E	S618	K615T	615	Missense	distal	-3	no	31.832	31.221	EPSD	TCGA;ICGC;COSMIC	22.404	Down-regulation
CK1_CK1_CK1-D_CSNK1E_ST	O14641	DVL2	P49674	CSNK1E	S618	E623G	623	Missense	distal	5	no	31.832	32.669	EPSD	TCGA;ICGC	22.404	Up-regulation
CK1_CK1_CK1-D_CSNK1E_ST	O14641	DVL2	P49674	CSNK1E	S620	E613K	613	Missense	distal	-7	no	24.754	24.755	EPSD	TCGA;ICGC;COSMIC	22.404	Up-regulation
CK1_CK1_CK1-D_CSNK1E_ST	O14641	DVL2	P49674	CSNK1E	S620	K615T	615	Missense	distal	-5	no	24.754	25.009	EPSD	TCGA;ICGC;COSMIC	22.404	Up-regulation
CK1_CK1_CK1-D_CSNK1E_ST	O14641	DVL2	P49674	CSNK1E	S620	E623G	623	Missense	distal	3	no	24.754	27.472	EPSD	TCGA;ICGC	22.404	Up-regulation
CK1_CK1_CK1-D_CSNK1E_ST	O14641	DVL2	P49674	CSNK1E	S622	K615T	615	Missense	distal	-7	no	39.245	39.248	EPSD	TCGA;ICGC;COSMIC	22.404	Up-regulation
CK1_CK1_CK1-D_CSNK1E_ST	O14641	DVL2	P49674	CSNK1E	S622	E623G	623	Missense	proximal	1	no	39.245	38.899	EPSD	TCGA;ICGC	22.404	Down-regulation
CK1_CK1_CK1-D_CSNK1E_ST	O14641	DVL2	P49674	CSNK1E	S626	R632W	632	Missense	distal	6	no	33.690	28.734	EPSD	TCGA;ICGC;COSMIC	22.404	Down-regulation
CK1_CK1_CK1-D_CSNK1E_ST	O14641	DVL2	P49674	CSNK1E	S626	E623G	623	Missense	distal	-3	no	33.690	36.340	EPSD	TCGA;ICGC	22.404	Up-regulation
CK1_CK1_CK1-D_CSNK1E_ST	O14641	DVL2	P49674	CSNK1E	S630	R632W	632	Missense	proximal	2	no	25.061	24.939	EPSD	TCGA;ICGC;COSMIC	22.404	Down-regulation
CK1_CK1_CK1-D_CSNK1E_ST	O14641	DVL2	P49674	CSNK1E	S638	R632W	632	Missense	distal	-6	no	27.041	26.751	EPSD	TCGA;ICGC;COSMIC	22.404	Down-regulation
CK1_CK1_CK1-D_CSNK1E_ST	Q13148	TARDBP	P49674	CSNK1E	T88	S91L	91	Missense	distal	3	no	24.176	17.373	EPSD	TCGA;ICGC;COSMIC	22.404	Loss
CK1_CK1_CK1-D_CSNK1E_ST	Q13148	TARDBP	P49674	CSNK1E	S91	S91L	91	Missense	central	0	yes	22.843	0.000	EPSD	TCGA;ICGC;COSMIC	22.404	Loss
CK1_CK1_CK1-D_CSNK1E_ST	Q13148	TARDBP	P49674	CSNK1E	S92	A99T	99	Missense	distal	7	no	27.727	27.836	EPSD	TCGA;ICGC;COSMIC	22.404	Up-regulation
CK1_CK1_CK1-D_CSNK1E_ST	Q13148	TARDBP	P49674	CSNK1E	S92	S91L	91	Missense	proximal	-1	no	27.727	19.420	EPSD	TCGA;ICGC;COSMIC	22.404	Loss
CK1_CK1_CK1-D_CSNK1E_ST	Q13148	TARDBP	P49674	CSNK1E	S305	G304S	304	Missense	proximal	-1	no	23.258	24.438	EPSD	TCGA;COSMIC	22.404	Up-regulation
CK1_CK1_CK1-D_CSNK1E_ST	Q13148	TARDBP	P49674	CSNK1E	S389	S393P	393	Missense	distal	4	no	25.241	25.275	EPSD	TCGA;COSMIC	22.404	Up-regulation
CK1_CK1_CK1-D_CSNK1E_ST	Q13148	TARDBP	P49674	CSNK1E	S389	S393L	393	Missense	distal	4	no	25.241	25.385	EPSD	TCGA;COSMIC	22.404	Up-regulation
CK1_CK1_CK1-D_CSNK1E_ST	Q13148	TARDBP	P49674	CSNK1E	S404	S407C	407	Missense	distal	3	no	23.075	13.983	EPSD	TCGA;COSMIC	22.404	Loss
CK1_CK1_CK1-D_CSNK1E_ST	O75581	LRP6	P49674	CSNK1E	S122	E115D	115	Missense	distal	-7	no	27.140	27.141	EPSD	TCGA;ICGC;COSMIC	22.404	Up-regulation
CK1_CK1_CK1-D_CSNK1E_ST	O75581	LRP6	P49674	CSNK1E	S172	N178S	178	Missense	distal	6	no	21.764	24.956	EPSD	TCGA;ICGC	22.404	Gain
CK1_CK1_CK1-D_CSNK1E_ST	O75581	LRP6	P49674	CSNK1E	S1420	A1419S	1419	Missense	proximal	-1	no	33.744	30.069	PhosphoSitePlus;EPSD	TCGA;COSMIC	22.404	Down-regulation
CK1_CK1_CK1-D_CSNK1E_ST	O75581	LRP6	P49674	CSNK1E	S1430	L1432V	1432	Missense	proximal	2	no	20.331	23.352	EPSD	TCGA;COSMIC	22.404	Gain
CK1_CK1_CK1-D_CSNK1E_ST	O75581	LRP6	P49674	CSNK1E	S1431	S1435T	1435	Missense	distal	4	no	36.080	36.153	EPSD;PhosphoSitePlus	TCGA	22.404	Up-regulation
CK1_CK1_CK1-D_CSNK1E_ST	O75581	LRP6	P49674	CSNK1E	S1431	S1431Y	1431	Missense	central	0	yes	36.080	0.000	EPSD;PhosphoSitePlus	TCGA;COSMIC	22.404	Loss
CK1_CK1_CK1-D_CSNK1E_ST	O75581	LRP6	P49674	CSNK1E	S1431	S1431F	1431	Missense	central	0	yes	36.080	0.000	EPSD;PhosphoSitePlus	TCGA;COSMIC	22.404	Loss
CK1_CK1_CK1-D_CSNK1E_ST	O75581	LRP6	P49674	CSNK1E	S1431	L1432V	1432	Missense	proximal	1	no	36.080	36.416	EPSD;PhosphoSitePlus	TCGA;COSMIC	22.404	Up-regulation
CK1_CK1_CK1-D_CSNK1E_ST	O75581	LRP6	P49674	CSNK1E	S1431	S1433A	1433	Missense	proximal	2	no	36.080	38.742	EPSD;PhosphoSitePlus	TCGA	22.404	Up-regulation
CK1_CK1_CK1-D_CSNK1E_ST	O75581	LRP6	P49674	CSNK1E	S1444	S1447C	1447	Missense	distal	3	no	30.982	21.890	EPSD	TCGA;COSMIC	22.404	Loss
CK1_CK1_CK1-D_CSNK1E_ST	O75581	LRP6	P49674	CSNK1E	S1444	R1441Q	1441	Missense	distal	-3	no	30.982	30.821	EPSD	TCGA;COSMIC	22.404	Down-regulation
CK1_CK1_CK1-D_CSNK1E_ST	O75581	LRP6	P49674	CSNK1E	S1444	M1445I	1445	Missense	proximal	1	no	30.982	30.466	EPSD	TCGA;COSMIC	22.404	Down-regulation
CK1_CK1_CK1-D_CSNK1E_ST	O75581	LRP6	P49674	CSNK1E	S1455	R1462P	1462	Missense	distal	7	no	23.599	23.501	EPSD	TCGA;COSMIC	22.404	Down-regulation
CK1_CK1_CK1-D_CSNK1E_ST	O75581	LRP6	P49674	CSNK1E	S1455	S1456N	1456	Missense	proximal	1	no	23.599	23.270	EPSD	TCGA	22.404	Down-regulation
CK1_CK1_CK1-D_CSNK1E_ST	O75581	LRP6	P49674	CSNK1E	S1455	G1454R	1454	Missense	proximal	-1	no	23.599	18.516	EPSD	TCGA;COSMIC	22.404	Loss
CK1_CK1_CK1-D_CSNK1E_ST	O75581	LRP6	P49674	CSNK1E	T1466	R1462P	1462	Missense	distal	-4	no	23.177	24.847	EPSD	TCGA;COSMIC	22.404	Up-regulation
CK1_CK1_CK1-D_CSNK1E_ST	O75581	LRP6	P49674	CSNK1E	S1469	R1462P	1462	Missense	distal	-7	no	30.665	30.670	EPSD	TCGA;COSMIC	22.404	Up-regulation
CK1_CK1_CK1-D_CSNK1E_ST	O75581	LRP6	P49674	CSNK1E	S1544	Y1541S	1541	Missense	distal	-3	no	23.885	28.115	EPSD	TCGA;COSMIC	22.404	Up-regulation
CK1_CK1_CK1-D_CSNK1E_ST	O75581	LRP6	P49674	CSNK1E	S1544	R1545Q	1545	Missense	proximal	1	no	23.885	23.496	EPSD	TCGA;COSMIC	22.404	Down-regulation
CK1_CK1_CK1-D_CSNK1E_ST	P12830	CDH1	P49674	CSNK1E	S237	E243Q	243	Missense	distal	6	no	20.337	23.266	EPSD	TCGA;ICGC;COSMIC	22.404	Gain
CK1_CK1_CK1-D_CSNK1E_ST	P12830	CDH1	P49674	CSNK1E	T576	D569E	569	Missense	distal	-7	no	32.821	32.820	EPSD	TCGA;COSMIC;CCLE	22.404	Down-regulation
CK1_CK1_CK1-D_CSNK1E_ST	P12830	CDH1	P49674	CSNK1E	S844	S850F	850	Missense	distal	6	no	39.355	36.150	PhosphoSitePlus	TCGA;COSMIC	22.404	Down-regulation
CK1_CK1_CK1-D_CSNK1E_ST	P12830	CDH1	P49674	CSNK1E	S844	E841K	841	Missense	distal	-3	no	39.355	40.445	PhosphoSitePlus	TCGA;COSMIC	22.404	Up-regulation
CK1_CK1_CK1-D_CSNK1E_ST	P12830	CDH1	P49674	CSNK1E	S847	S850F	850	Missense	distal	3	no	27.367	24.840	EPSD	TCGA;COSMIC	22.404	Down-regulation
CK1_CK1_CK1-D_CSNK1E_ST	P12830	CDH1	P49674	CSNK1E	S847	E841K	841	Missense	distal	-6	no	27.367	29.499	EPSD	TCGA;COSMIC	22.404	Up-regulation
CK1_CK1_CK1-D_CSNK1E_ST	P12830	CDH1	P49674	CSNK1E	S851	S850F	850	Missense	proximal	-1	no	29.793	22.087	EPSD	TCGA;COSMIC	22.404	Loss
CK1_CK1_CK1-D_CSNK1E_ST	P12830	CDH1	P49674	CSNK1E	S853	S850F	850	Missense	distal	-3	no	33.379	30.943	EPSD	TCGA;COSMIC	22.404	Down-regulation
CK1_CK1_CK1-D_CSNK1E_ST	Q13114	TRAF3	P49674	CSNK1E	S349	S356F	356	Missense	distal	7	no	37.747	38.480	PhosphoSitePlus	TCGA;COSMIC	22.404	Up-regulation
CK1_CK1_CK1-D_CSNK1E_ST	Q13114	TRAF3	P49674	CSNK1E	S366	L364P	364	Missense	proximal	-2	no	19.679	24.964	EPSD	TCGA	22.404	Gain
CK1_CK1_CK1-D_CSNK1E_ST	P25054	APC	P49674	CSNK1E	S5	A2D	2	Missense	distal	-3	no	23.043	24.727	EPSD	TCGA;COSMIC	22.404	Up-regulation
CK1_CK1_CK1-D_CSNK1E_ST	P25054	APC	P49674	CSNK1E	S5	A3T	3	Missense	proximal	-2	no	23.043	19.396	EPSD	TCGA;ICGC;COSMIC	22.404	Loss
CK1_CK1_CK1-D_CSNK1E_ST	P25054	APC	P49674	CSNK1E	T39	M44V	44	Missense	distal	5	no	32.352	33.562	EPSD	TCGA;ICGC;COSMIC	22.404	Up-regulation
CK1_CK1_CK1-D_CSNK1E_ST	P25054	APC	P49674	CSNK1E	S62	D67Y	67	Missense	distal	5	no	22.018	23.580	EPSD	TCGA;ICGC;COSMIC	22.404	Gain
CK1_CK1_CK1-D_CSNK1E_ST	P25054	APC	P49674	CSNK1E	S102	G108A	108	Missense	distal	6	no	29.973	28.790	EPSD	TCGA;ICGC;COSMIC	22.404	Down-regulation
CK1_CK1_CK1-D_CSNK1E_ST	P25054	APC	P49674	CSNK1E	S102	E109A	109	Missense	distal	7	no	29.973	30.232	EPSD	TCGA;ICGC;COSMIC	22.404	Up-regulation
CK1_CK1_CK1-D_CSNK1E_ST	P25054	APC	P49674	CSNK1E	S111	G108A	108	Missense	distal	-3	no	23.480	21.692	EPSD	TCGA;ICGC;COSMIC	22.404	Loss
CK1_CK1_CK1-D_CSNK1E_ST	P25054	APC	P49674	CSNK1E	S111	E109A	109	Missense	proximal	-2	no	23.480	27.640	EPSD	TCGA;ICGC;COSMIC	22.404	Up-regulation
CK1_CK1_CK1-D_CSNK1E_ST	P25054	APC	P49674	CSNK1E	S290	R283Q	283	Missense	distal	-7	no	32.387	32.392	EPSD	TCGA;ICGC;COSMIC	22.404	Up-regulation
CK1_CK1_CK1-D_CSNK1E_ST	P25054	APC	P49674	CSNK1E	S290	S294F	294	Missense	distal	4	no	32.387	32.505	EPSD	TCGA;ICGC;COSMIC	22.404	Up-regulation
CK1_CK1_CK1-D_CSNK1E_ST	P25054	APC	P49674	CSNK1E	S290	A289V	289	Missense	proximal	-1	no	32.387	24.719	EPSD	TCGA;ICGC;COSMIC	22.404	Down-regulation
CK1_CK1_CK1-D_CSNK1E_ST	P25054	APC	P49674	CSNK1E	S293	S299C	299	Missense	distal	6	no	26.270	21.107	EPSD	TCGA;ICGC;COSMIC	22.404	Loss
CK1_CK1_CK1-D_CSNK1E_ST	P25054	APC	P49674	CSNK1E	S293	S294F	294	Missense	proximal	1	no	26.270	25.233	EPSD	TCGA;ICGC;COSMIC	22.404	Down-regulation
CK1_CK1_CK1-D_CSNK1E_ST	P25054	APC	P49674	CSNK1E	S293	A289V	289	Missense	distal	-4	no	26.270	20.868	EPSD	TCGA;ICGC;COSMIC	22.404	Loss
CK1_CK1_CK1-D_CSNK1E_ST	P25054	APC	P49674	CSNK1E	S296	S299C	299	Missense	distal	3	no	24.861	15.769	EPSD	TCGA;ICGC;COSMIC	22.404	Loss
CK1_CK1_CK1-D_CSNK1E_ST	P25054	APC	P49674	CSNK1E	S296	R302Q	302	Missense	distal	6	no	24.861	23.796	EPSD	TCGA;ICGC;COSMIC	22.404	Down-regulation
CK1_CK1_CK1-D_CSNK1E_ST	P25054	APC	P49674	CSNK1E	S296	S294F	294	Missense	proximal	-2	no	24.861	16.824	EPSD	TCGA;ICGC;COSMIC	22.404	Loss
CK1_CK1_CK1-D_CSNK1E_ST	P25054	APC	P49674	CSNK1E	S296	A289V	289	Missense	distal	-7	no	24.861	24.860	EPSD	TCGA;ICGC;COSMIC	22.404	Down-regulation
CK1_CK1_CK1-D_CSNK1E_ST	P25054	APC	P49674	CSNK1E	S747	P745H	745	Missense	proximal	-2	no	32.569	29.166	EPSD	TCGA;ICGC;COSMIC	22.404	Down-regulation
CK1_CK1_CK1-D_CSNK1E_ST	P25054	APC	P49674	CSNK1E	S747	N741S	741	Missense	distal	-6	no	32.569	33.002	EPSD	TCGA;ICGC;COSMIC	22.404	Up-regulation
CK1_CK1_CK1-D_CSNK1E_ST	P25054	APC	P49674	CSNK1E	S844	D842V	842	Missense	proximal	-2	no	20.317	23.222	EPSD	TCGA;ICGC;COSMIC	22.404	Gain
CK1_CK1_CK1-D_CSNK1E_ST	P25054	APC	P49674	CSNK1E	T899	S906Y	906	Missense	distal	7	no	22.179	23.065	EPSD	TCGA;ICGC;COSMIC	22.404	Gain
CK1_CK1_CK1-D_CSNK1E_ST	P25054	APC	P49674	CSNK1E	S1117	N1124I	1124	Missense	distal	7	no	22.552	22.356	EPSD	TCGA;ICGC;COSMIC	22.404	Loss
CK1_CK1_CK1-D_CSNK1E_ST	P25054	APC	P49674	CSNK1E	S1117	H1119R	1119	Missense	proximal	2	no	22.552	21.231	EPSD	TCGA;ICGC;COSMIC	22.404	Loss
CK1_CK1_CK1-D_CSNK1E_ST	P25054	APC	P49674	CSNK1E	S1117	N1122D	1122	Missense	distal	5	no	22.552	22.207	EPSD	TCGA;ICGC;COSMIC	22.404	Loss
CK1_CK1_CK1-D_CSNK1E_ST	P25054	APC	P49674	CSNK1E	S1215	T1218M	1218	Missense	distal	3	no	20.873	25.359	EPSD	TCGA;ICGC;COSMIC	22.404	Gain
CK1_CK1_CK1-D_CSNK1E_ST	P25054	APC	P49674	CSNK1E	S1219	T1218M	1218	Missense	proximal	-1	no	23.419	18.682	EPSD	TCGA;ICGC;COSMIC	22.404	Loss
CK1_CK1_CK1-D_CSNK1E_ST	P25054	APC	P49674	CSNK1E	S1219	S1215I	1215	Missense	distal	-4	no	23.419	19.081	EPSD	TCGA;ICGC;COSMIC	22.404	Loss
CK1_CK1_CK1-D_CSNK1E_ST	P25054	APC	P49674	CSNK1E	S1219	S1219F	1219	Missense	central	0	yes	23.419	0.000	EPSD	TCGA;ICGC	22.404	Loss
CK1_CK1_CK1-D_CSNK1E_ST	P25054	APC	P49674	CSNK1E	S1279	S1278L	1278	Missense	proximal	-1	no	36.697	28.390	PhosphoSitePlus;EPSD	TCGA;ICGC;COSMIC	22.404	Down-regulation
CK1_CK1_CK1-D_CSNK1E_ST	P25054	APC	P49674	CSNK1E	S1279	S1272L	1272	Missense	distal	-7	no	36.697	36.691	PhosphoSitePlus;EPSD	TCGA;ICGC;COSMIC	22.404	Down-regulation
CK1_CK1_CK1-D_CSNK1E_ST	P25054	APC	P49674	CSNK1E	S1279	L1277V	1277	Missense	proximal	-2	no	36.697	42.184	PhosphoSitePlus;EPSD	TCGA	22.404	Up-regulation
CK1_CK1_CK1-D_CSNK1E_ST	P25054	APC	P49674	CSNK1E	S1340	S1343C	1343	Missense	distal	3	no	23.203	14.111	EPSD	TCGA;ICGC;COSMIC	22.404	Loss
CK1_CK1_CK1-D_CSNK1E_ST	P25054	APC	P49674	CSNK1E	S1344	S1343C	1343	Missense	proximal	-1	no	23.502	16.229	EPSD	TCGA;ICGC;COSMIC	22.404	Loss
CK1_CK1_CK1-D_CSNK1E_ST	P25054	APC	P49674	CSNK1E	T1368	Q1367E	1367	Missense	proximal	-1	no	27.840	31.727	EPSD	TCGA;ICGC;COSMIC	22.404	Up-regulation
CK1_CK1_CK1-D_CSNK1E_ST	P25054	APC	P49674	CSNK1E	T1368	P1361S	1361	Missense	distal	-7	no	27.840	27.841	EPSD	TCGA;ICGC;COSMIC	22.404	Up-regulation
CK1_CK1_CK1-D_CSNK1E_ST	P25054	APC	P49674	CSNK1E	S1389	R1386K	1386	Missense	distal	-3	no	25.057	25.611	EPSD	TCGA;ICGC;COSMIC	22.404	Up-regulation
CK1_CK1_CK1-D_CSNK1E_ST	P25054	APC	P49674	CSNK1E	S1389	S1389F	1389	Missense	central	0	yes	25.057	0.000	EPSD	TCGA;ICGC;COSMIC	22.404	Loss
CK1_CK1_CK1-D_CSNK1E_ST	P25054	APC	P49674	CSNK1E	S1389	L1393I	1393	Missense	distal	4	no	25.057	24.887	EPSD	TCGA;ICGC;COSMIC	22.404	Down-regulation
CK1_CK1_CK1-D_CSNK1E_ST	P25054	APC	P49674	CSNK1E	S1392	R1386K	1386	Missense	distal	-6	no	34.913	36.051	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	22.404	Up-regulation
CK1_CK1_CK1-D_CSNK1E_ST	P25054	APC	P49674	CSNK1E	S1392	S1389F	1389	Missense	distal	-3	no	34.913	32.477	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	22.404	Down-regulation
CK1_CK1_CK1-D_CSNK1E_ST	P25054	APC	P49674	CSNK1E	S1392	L1393I	1393	Missense	proximal	1	no	34.913	35.536	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	22.404	Up-regulation
CK1_CK1_CK1-D_CSNK1E_ST	P25054	APC	P49674	CSNK1E	S1392	R1399H	1399	Missense	distal	7	no	34.913	35.046	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	22.404	Up-regulation
CK1_CK1_CK1-D_CSNK1E_ST	P25054	APC	P49674	CSNK1E	S1505	A1508D	1508	Missense	distal	3	no	29.860	36.805	EPSD	TCGA;ICGC	22.404	Up-regulation
CK1_CK1_CK1-D_CSNK1E_ST	P25054	APC	P49674	CSNK1E	S1539	E1544Q	1544	Missense	distal	5	no	23.087	22.275	EPSD	TCGA;ICGC;COSMIC	22.404	Loss
CK1_CK1_CK1-D_CSNK1E_ST	P25054	APC	P49674	CSNK1E	S1539	E1540G	1540	Missense	proximal	1	no	23.087	22.741	EPSD	TCGA;ICGC;COSMIC	22.404	Down-regulation
CK1_CK1_CK1-D_CSNK1E_ST	P25054	APC	P49674	CSNK1E	S1539	S1539L	1539	Missense	central	0	yes	23.087	0.000	EPSD	TCGA;ICGC;COSMIC	22.404	Loss
CK1_CK1_CK1-D_CSNK1E_ST	P25054	APC	P49674	CSNK1E	S1610	P1613H	1613	Missense	distal	3	no	23.379	15.981	EPSD	TCGA;ICGC	22.404	Loss
CK1_CK1_CK1-D_CSNK1E_ST	P25054	APC	P49674	CSNK1E	S1656	D1659V	1659	Missense	distal	3	no	34.573	25.202	EPSD	TCGA;ICGC;COSMIC	22.404	Down-regulation
CK1_CK1_CK1-D_CSNK1E_ST	P25054	APC	P49674	CSNK1E	S1754	Q1749K	1749	Missense	distal	-5	no	25.033	24.429	EPSD	TCGA;ICGC;COSMIC	22.404	Down-regulation
CK1_CK1_CK1-D_CSNK1E_ST	P25054	APC	P49674	CSNK1E	S1754	S1758F	1758	Missense	distal	4	no	25.033	25.151	EPSD	TCGA;ICGC;COSMIC	22.404	Up-regulation
CK1_CK1_CK1-D_CSNK1E_ST	P25054	APC	P49674	CSNK1E	S1754	S1757Y	1757	Missense	distal	3	no	25.033	15.162	EPSD	TCGA;ICGC	22.404	Loss
CK1_CK1_CK1-D_CSNK1E_ST	P25054	APC	P49674	CSNK1E	S1754	A1755V	1755	Missense	proximal	1	no	25.033	25.005	EPSD	TCGA;ICGC;COSMIC	22.404	Down-regulation
CK1_CK1_CK1-D_CSNK1E_ST	P25054	APC	P49674	CSNK1E	S1757	S1758F	1758	Missense	proximal	1	no	26.313	25.277	EPSD	TCGA;ICGC;COSMIC	22.404	Down-regulation
CK1_CK1_CK1-D_CSNK1E_ST	P25054	APC	P49674	CSNK1E	S1757	S1757Y	1757	Missense	central	0	yes	26.313	0.000	EPSD	TCGA;ICGC	22.404	Loss
CK1_CK1_CK1-D_CSNK1E_ST	P25054	APC	P49674	CSNK1E	S1757	A1755V	1755	Missense	proximal	-2	no	26.313	24.327	EPSD	TCGA;ICGC;COSMIC	22.404	Down-regulation
CK1_CK1_CK1-D_CSNK1E_ST	P25054	APC	P49674	CSNK1E	S1896	E1891Q	1891	Missense	distal	-5	no	24.125	23.848	EPSD	TCGA;ICGC;COSMIC	22.404	Down-regulation
CK1_CK1_CK1-D_CSNK1E_ST	P25054	APC	P49674	CSNK1E	S1896	A1892V	1892	Missense	distal	-4	no	24.125	18.724	EPSD	TCGA;ICGC;COSMIC	22.404	Loss
CK1_CK1_CK1-D_CSNK1E_ST	P25054	APC	P49674	CSNK1E	S2110	H2116Q	2116	Missense	distal	6	no	29.100	30.268	EPSD	TCGA;ICGC;COSMIC	22.404	Up-regulation
CK1_CK1_CK1-D_CSNK1E_ST	P25054	APC	P49674	CSNK1E	S2110	G2107S	2107	Missense	distal	-3	no	29.100	28.824	EPSD	TCGA;ICGC;COSMIC	22.404	Down-regulation
CK1_CK1_CK1-D_CSNK1E_ST	P25054	APC	P49674	CSNK1E	S2241	T2243A	2243	Missense	proximal	2	no	30.815	32.643	EPSD	TCGA;ICGC	22.404	Up-regulation
CK1_CK1_CK1-D_CSNK1E_ST	P25054	APC	P49674	CSNK1E	S2241	S2242N	2242	Missense	proximal	1	no	30.815	30.487	EPSD	TCGA;ICGC;COSMIC	22.404	Down-regulation
CK1_CK1_CK1-D_CSNK1E_ST	P25054	APC	P49674	CSNK1E	S2241	P2234S	2234	Missense	distal	-7	no	30.815	30.816	EPSD	TCGA;ICGC;COSMIC	22.404	Up-regulation
CK1_CK1_CK1-D_CSNK1E_ST	P25054	APC	P49674	CSNK1E	S2241	S2242I	2242	Missense	proximal	1	no	30.815	30.786	EPSD	TCGA;ICGC	22.404	Down-regulation
CK1_CK1_CK1-D_CSNK1E_ST	P25054	APC	P49674	CSNK1E	S2241	P2245H	2245	Missense	distal	4	no	30.815	30.916	EPSD	TCGA;ICGC	22.404	Up-regulation
CK1_CK1_CK1-D_CSNK1E_ST	P25054	APC	P49674	CSNK1E	S2244	T2243A	2243	Missense	proximal	-1	no	27.434	33.209	EPSD	TCGA;ICGC	22.404	Up-regulation
CK1_CK1_CK1-D_CSNK1E_ST	P25054	APC	P49674	CSNK1E	S2244	G2250V	2250	Missense	distal	6	no	27.434	24.750	EPSD	TCGA;ICGC;COSMIC	22.404	Down-regulation
CK1_CK1_CK1-D_CSNK1E_ST	P25054	APC	P49674	CSNK1E	S2244	S2242N	2242	Missense	proximal	-2	no	27.434	20.322	EPSD	TCGA;ICGC;COSMIC	22.404	Loss
CK1_CK1_CK1-D_CSNK1E_ST	P25054	APC	P49674	CSNK1E	S2244	S2242I	2242	Missense	proximal	-2	no	27.434	26.646	EPSD	TCGA;ICGC	22.404	Down-regulation
CK1_CK1_CK1-D_CSNK1E_ST	P25054	APC	P49674	CSNK1E	S2244	P2245H	2245	Missense	proximal	1	no	27.434	27.428	EPSD	TCGA;ICGC	22.404	Down-regulation
CK1_CK1_CK1-D_CSNK1E_ST	P25054	APC	P49674	CSNK1E	S2247	T2243A	2243	Missense	distal	-4	no	20.654	23.188	EPSD	TCGA;ICGC	22.404	Gain
CK1_CK1_CK1-D_CSNK1E_ST	P25054	APC	P49674	CSNK1E	S2270	S2277A	2277	Missense	distal	7	no	22.607	23.049	EPSD	TCGA;ICGC;COSMIC	22.404	Up-regulation
CK1_CK1_CK1-D_CSNK1E_ST	P25054	APC	P49674	CSNK1E	S2302	S2307L	2307	Missense	distal	5	no	23.817	25.102	EPSD	TCGA;ICGC;COSMIC;CCLE	22.404	Up-regulation
CK1_CK1_CK1-D_CSNK1E_ST	P25054	APC	P49674	CSNK1E	S2302	S2300C	2300	Missense	proximal	-2	no	23.817	16.643	EPSD	TCGA;ICGC;COSMIC	22.404	Loss
CK1_CK1_CK1-D_CSNK1E_ST	P25054	APC	P49674	CSNK1E	S2302	S2300Y	2300	Missense	proximal	-2	no	23.817	18.282	EPSD	TCGA	22.404	Loss
CK1_CK1_CK1-D_CSNK1E_ST	P25054	APC	P49674	CSNK1E	S2304	S2307L	2307	Missense	distal	3	no	23.361	16.557	EPSD	TCGA;ICGC;COSMIC;CCLE	22.404	Loss
CK1_CK1_CK1-D_CSNK1E_ST	P25054	APC	P49674	CSNK1E	S2304	S2300C	2300	Missense	distal	-4	no	23.361	16.761	EPSD	TCGA;ICGC;COSMIC	22.404	Loss
CK1_CK1_CK1-D_CSNK1E_ST	P25054	APC	P49674	CSNK1E	S2304	S2300Y	2300	Missense	distal	-4	no	23.361	18.220	EPSD	TCGA	22.404	Loss
CK1_CK1_CK1-D_CSNK1E_ST	P25054	APC	P49674	CSNK1E	S2307	A2313S	2313	Missense	distal	6	no	21.287	24.986	EPSD	TCGA;ICGC;COSMIC	22.404	Gain
CK1_CK1_CK1-D_CSNK1E_ST	P25054	APC	P49674	CSNK1E	S2359	G2360S	2360	Missense	proximal	1	no	22.635	23.615	EPSD	TCGA;ICGC;COSMIC	22.404	Up-regulation
CK1_CK1_CK1-D_CSNK1E_ST	P25054	APC	P49674	CSNK1E	S2390	A2388V	2388	Missense	proximal	-2	no	23.664	21.678	EPSD	TCGA;ICGC;COSMIC;CCLE	22.404	Loss
CK1_CK1_CK1-D_CSNK1E_ST	P25054	APC	P49674	CSNK1E	S2396	Q2403H	2403	Missense	distal	7	no	22.425	22.455	EPSD	TCGA;ICGC;COSMIC	22.404	Up-regulation
CK1_CK1_CK1-D_CSNK1E_ST	P25054	APC	P49674	CSNK1E	S2396	L2401P	2401	Missense	distal	5	no	22.425	21.433	EPSD	TCGA;ICGC;COSMIC	22.404	Loss
CK1_CK1_CK1-D_CSNK1E_ST	P25054	APC	P49674	CSNK1E	T2422	S2429F	2429	Missense	distal	7	no	23.894	24.627	EPSD	TCGA;COSMIC	22.404	Up-regulation
CK1_CK1_CK1-D_CSNK1E_ST	P25054	APC	P49674	CSNK1E	S2425	S2429F	2429	Missense	distal	4	no	32.289	32.406	EPSD	TCGA;COSMIC	22.404	Up-regulation
CK1_CK1_CK1-D_CSNK1E_ST	P25054	APC	P49674	CSNK1E	S2425	D2430H	2430	Missense	distal	5	no	32.289	32.565	EPSD	TCGA;ICGC;COSMIC	22.404	Up-regulation
CK1_CK1_CK1-D_CSNK1E_ST	P25054	APC	P49674	CSNK1E	S2464	S2464Y	2464	Missense	central	0	yes	27.851	0.000	EPSD	TCGA;ICGC;COSMIC	22.404	Loss
CK1_CK1_CK1-D_CSNK1E_ST	P25054	APC	P49674	CSNK1E	S2473	A2472D	2472	Missense	proximal	-1	no	31.375	26.011	EPSD	TCGA;ICGC	22.404	Down-regulation
CK1_CK1_CK1-D_CSNK1E_ST	P25054	APC	P49674	CSNK1E	S2533	P2540S	2540	Missense	distal	7	no	28.080	27.876	EPSD	TCGA;ICGC;COSMIC	22.404	Down-regulation
CK1_CK1_CK1-D_CSNK1E_ST	P25054	APC	P49674	CSNK1E	S2533	H2532Y	2532	Missense	proximal	-1	no	28.080	27.758	EPSD	TCGA;ICGC;COSMIC	22.404	Down-regulation
CK1_CK1_CK1-D_CSNK1E_ST	P25054	APC	P49674	CSNK1E	S2535	I2541V	2541	Missense	distal	6	no	26.508	24.909	EPSD	TCGA;ICGC;COSMIC	22.404	Down-regulation
CK1_CK1_CK1-D_CSNK1E_ST	P25054	APC	P49674	CSNK1E	S2535	P2540S	2540	Missense	distal	5	no	26.508	26.215	EPSD	TCGA;ICGC;COSMIC	22.404	Down-regulation
CK1_CK1_CK1-D_CSNK1E_ST	P25054	APC	P49674	CSNK1E	S2535	H2532Y	2532	Missense	distal	-3	no	26.508	27.059	EPSD	TCGA;ICGC;COSMIC	22.404	Up-regulation
CK1_CK1_CK1-D_CSNK1E_ST	P25054	APC	P49674	CSNK1E	T2546	R2543K	2543	Missense	distal	-3	no	24.642	25.195	EPSD	TCGA	22.404	Up-regulation
CK1_CK1_CK1-D_CSNK1E_ST	P25054	APC	P49674	CSNK1E	T2546	R2549H	2549	Missense	distal	3	no	24.642	18.306	EPSD	TCGA;ICGC;COSMIC	22.404	Loss
CK1_CK1_CK1-D_CSNK1E_ST	P25054	APC	P49674	CSNK1E	T2546	I2541V	2541	Missense	distal	-5	no	24.642	25.041	EPSD	TCGA;ICGC;COSMIC	22.404	Up-regulation
CK1_CK1_CK1-D_CSNK1E_ST	P25054	APC	P49674	CSNK1E	T2546	P2540S	2540	Missense	distal	-6	no	24.642	25.298	EPSD	TCGA;ICGC;COSMIC	22.404	Up-regulation
CK1_CK1_CK1-D_CSNK1E_ST	P25054	APC	P49674	CSNK1E	T2546	E2550V	2550	Missense	distal	4	no	24.642	24.588	EPSD	TCGA;ICGC;COSMIC	22.404	Down-regulation
CK1_CK1_CK1-D_CSNK1E_ST	P25054	APC	P49674	CSNK1E	T2563	S2569N	2569	Missense	distal	6	no	24.739	21.546	EPSD	TCGA;ICGC;COSMIC	22.404	Loss
CK1_CK1_CK1-D_CSNK1E_ST	P25054	APC	P49674	CSNK1E	S2569	S2569N	2569	Missense	central	0	yes	23.725	0.000	EPSD	TCGA;ICGC;COSMIC	22.404	Loss
CK1_CK1_CK1-D_CSNK1E_ST	P25054	APC	P49674	CSNK1E	S2569	L2574I	2574	Missense	distal	5	no	23.725	23.433	EPSD	TCGA;ICGC;COSMIC	22.404	Down-regulation
CK1_CK1_CK1-D_CSNK1E_ST	P25054	APC	P49674	CSNK1E	S2577	L2574I	2574	Missense	distal	-3	no	25.007	27.674	EPSD	TCGA;ICGC;COSMIC	22.404	Up-regulation
CK1_CK1_CK1-D_CSNK1E_ST	P25054	APC	P49674	CSNK1E	S2577	S2577P	2577	Missense	central	0	yes	25.007	0.000	EPSD	TCGA;ICGC	22.404	Loss
CK1_CK1_CK1-D_CSNK1E_ST	P25054	APC	P49674	CSNK1E	S2580	K2585I	2585	Missense	distal	5	no	32.695	33.016	EPSD	TCGA;ICGC;COSMIC	22.404	Up-regulation
CK1_CK1_CK1-D_CSNK1E_ST	P25054	APC	P49674	CSNK1E	S2580	L2574I	2574	Missense	distal	-6	no	32.695	34.151	EPSD	TCGA;ICGC;COSMIC	22.404	Up-regulation
CK1_CK1_CK1-D_CSNK1E_ST	P25054	APC	P49674	CSNK1E	S2580	S2577P	2577	Missense	distal	-3	no	32.695	33.129	EPSD	TCGA;ICGC	22.404	Up-regulation
CK1_CK1_CK1-D_CSNK1E_ST	P25054	APC	P49674	CSNK1E	S2625	N2624D	2624	Missense	proximal	-1	no	20.747	25.840	EPSD	TCGA;ICGC;COSMIC	22.404	Gain
CK1_CK1_CK1-D_CSNK1E_ST	P25054	APC	P49674	CSNK1E	S2765	R2759H	2759	Missense	distal	-6	no	33.220	33.903	EPSD	TCGA;ICGC;COSMIC	22.404	Up-regulation
CK1_CK1_CK1-D_CSNK1E_ST	P25054	APC	P49674	CSNK1E	S2768	G2775V	2775	Missense	distal	7	no	27.070	27.764	EPSD	TCGA;ICGC;COSMIC	22.404	Up-regulation
CK1_CK1_CK1-D_CSNK1E_ST	P25054	APC	P49674	CSNK1E	S2772	G2775V	2775	Missense	distal	3	no	23.426	17.541	EPSD	TCGA;ICGC;COSMIC	22.404	Loss
CK1_CK1_CK1-D_CSNK1E_ST	P25054	APC	P49674	CSNK1E	S2772	A2779V	2779	Missense	distal	7	no	23.426	23.882	EPSD	TCGA;ICGC;COSMIC	22.404	Up-regulation
CK1_CK1_CK1-D_CSNK1E_ST	P25054	APC	P49674	CSNK1E	T2776	R2780T	2780	Missense	distal	4	no	25.531	25.431	EPSD	TCGA;ICGC;COSMIC	22.404	Down-regulation
CK1_CK1_CK1-D_CSNK1E_ST	P25054	APC	P49674	CSNK1E	T2776	P2783L	2783	Missense	distal	7	no	25.531	25.917	EPSD	TCGA;ICGC;COSMIC	22.404	Up-regulation
CK1_CK1_CK1-D_CSNK1E_ST	P25054	APC	P49674	CSNK1E	T2776	G2775V	2775	Missense	proximal	-1	no	25.531	22.718	EPSD	TCGA;ICGC;COSMIC	22.404	Down-regulation
CK1_CK1_CK1-D_CSNK1E_ST	P25054	APC	P49674	CSNK1E	T2776	A2779V	2779	Missense	distal	3	no	25.531	23.106	EPSD	TCGA;ICGC;COSMIC	22.404	Down-regulation
CK1_CK1_CK1-D_CSNK1E_ST	P25054	APC	P49674	CSNK1E	S2793	S2794T	2794	Missense	proximal	1	no	26.193	25.581	EPSD	TCGA;ICGC;COSMIC	22.404	Down-regulation
CK1_CK1_CK1-D_CSNK1E_ST	P25054	APC	P49674	CSNK1E	S2797	R2801W	2801	Missense	distal	4	no	31.982	32.000	EPSD	TCGA;ICGC;COSMIC	22.404	Up-regulation
CK1_CK1_CK1-D_CSNK1E_ST	P25054	APC	P49674	CSNK1E	S2797	S2794T	2794	Missense	distal	-3	no	31.982	30.088	EPSD	TCGA;ICGC;COSMIC	22.404	Down-regulation
CK1_CK1_CK1-D_CSNK1E_ST	P25054	APC	P49674	CSNK1E	S2797	Q2804P	2804	Missense	distal	7	no	31.982	31.783	EPSD	TCGA	22.404	Down-regulation
CK1_CK1_CK1-D_CSNK1E_ST	P25054	APC	P49674	CSNK1E	T2798	R2801W	2801	Missense	distal	3	no	23.150	19.645	EPSD	TCGA;ICGC;COSMIC	22.404	Loss
CK1_CK1_CK1-D_CSNK1E_ST	P25054	APC	P49674	CSNK1E	T2798	S2794T	2794	Missense	distal	-4	no	23.150	21.509	EPSD	TCGA;ICGC;COSMIC	22.404	Loss
CK1_CK1_CK1-D_CSNK1E_ST	P25054	APC	P49674	CSNK1E	T2798	Q2804P	2804	Missense	distal	6	no	23.150	24.677	EPSD	TCGA	22.404	Up-regulation
CK1_CK1_CK1-D_CSNK1E_ST	P25054	APC	P49674	CSNK1E	S2825	T2823R	2823	Missense	proximal	-2	no	22.865	18.746	EPSD	TCGA;ICGC;COSMIC	22.404	Loss
CK1_CK1_CK1-D_CSNK1E_ST	P25054	APC	P49674	CSNK1E	S2826	T2823R	2823	Missense	distal	-3	no	24.690	24.747	EPSD	TCGA;ICGC;COSMIC	22.404	Up-regulation
CK1_CK1_CK1-D_CSNK1E_ST	P25054	APC	P49674	CSNK1E	T2828	T2823R	2823	Missense	distal	-5	no	26.711	26.641	EPSD	TCGA;ICGC;COSMIC	22.404	Down-regulation
CK1_CK1_CK1-D_CSNK1E_ST	P35222	CTNNB1	P49674	CSNK1E	T41	S45F	45	Missense	distal	4	no	35.952	36.070	EPSD	TCGA;COSMIC;GDSC;CCLE	22.404	Up-regulation
CK1_CK1_CK1-D_CSNK1E_ST	P35222	CTNNB1	P49674	CSNK1E	T41	G34R	34	Missense	distal	-7	no	35.952	35.948	EPSD	TCGA;COSMIC	22.404	Down-regulation
CK1_CK1_CK1-D_CSNK1E_ST	P35222	CTNNB1	P49674	CSNK1E	T41	S45P	45	Missense	distal	4	no	35.952	35.986	EPSD	TCGA;COSMIC;CCLE	22.404	Up-regulation
CK1_CK1_CK1-D_CSNK1E_ST	P35222	CTNNB1	P49674	CSNK1E	T41	G34V	34	Missense	distal	-7	no	35.952	35.951	EPSD	TCGA;COSMIC;CCLE	22.404	Down-regulation
CK1_CK1_CK1-D_CSNK1E_ST	P35222	CTNNB1	P49674	CSNK1E	T41	T41A	41	Missense	central	0	yes	35.952	0.000	EPSD	TCGA;COSMIC;GDSC;CCLE	22.404	Loss
CK1_CK1_CK1-D_CSNK1E_ST	P35222	CTNNB1	P49674	CSNK1E	T41	S37C	37	Missense	distal	-4	no	35.952	29.353	EPSD	TCGA;COSMIC;GDSC;CCLE	22.404	Down-regulation
CK1_CK1_CK1-D_CSNK1E_ST	P35222	CTNNB1	P49674	CSNK1E	T41	S37F	37	Missense	distal	-4	no	35.952	30.830	EPSD	TCGA;COSMIC;GDSC;CCLE	22.404	Down-regulation
CK1_CK1_CK1-D_CSNK1E_ST	P35222	CTNNB1	P49674	CSNK1E	T41	T41I	41	Missense	central	0	yes	35.952	0.000	EPSD	TCGA;COSMIC	22.404	Loss
CK1_CK1_CK1-D_CSNK1E_ST	P35222	CTNNB1	P49674	CSNK1E	T41	S45Y	45	Missense	distal	4	no	35.952	36.101	EPSD	TCGA;COSMIC	22.404	Up-regulation
CK1_CK1_CK1-D_CSNK1E_ST	P35222	CTNNB1	P49674	CSNK1E	T41	H36P	36	Missense	distal	-5	no	35.952	37.086	EPSD	TCGA;COSMIC;CCLE	22.404	Up-regulation
CK1_CK1_CK1-D_CSNK1E_ST	P35222	CTNNB1	P49674	CSNK1E	T41	I35S	35	Missense	distal	-6	no	35.952	35.778	EPSD	TCGA;COSMIC	22.404	Down-regulation
CK1_CK1_CK1-D_CSNK1E_ST	P35222	CTNNB1	P49674	CSNK1E	T41	S37Y	37	Missense	distal	-4	no	35.952	30.812	EPSD	TCGA;COSMIC	22.404	Down-regulation
CK1_CK1_CK1-D_CSNK1E_ST	P35222	CTNNB1	P49674	CSNK1E	T41	S37A	37	Missense	distal	-4	no	35.952	36.845	EPSD	TCGA;COSMIC;GDSC;CCLE	22.404	Up-regulation
CK1_CK1_CK1-D_CSNK1E_ST	P35222	CTNNB1	P49674	CSNK1E	T41	T41N	41	Missense	central	0	yes	35.952	0.000	EPSD	TCGA;COSMIC	22.404	Loss
CK1_CK1_CK1-D_CSNK1E_ST	P35222	CTNNB1	P49674	CSNK1E	T41	S45C	45	Missense	distal	4	no	35.952	36.130	EPSD	TCGA;COSMIC;GDSC;CCLE	22.404	Up-regulation
CK1_CK1_CK1-D_CSNK1E_ST	P35222	CTNNB1	P49674	CSNK1E	T41	S37P	37	Missense	distal	-4	no	35.952	34.137	EPSD	TCGA;COSMIC;GDSC;CCLE	22.404	Down-regulation
CK1_CK1_CK1-D_CSNK1E_ST	P35222	CTNNB1	P49674	CSNK1E	S45	S45F	45	Missense	central	0	yes	38.292	0.000	PhosphoSitePlus	TCGA;COSMIC;GDSC;CCLE	22.404	Loss
CK1_CK1_CK1-D_CSNK1E_ST	P35222	CTNNB1	P49674	CSNK1E	S45	S45P	45	Missense	central	0	yes	38.292	0.000	PhosphoSitePlus	TCGA;COSMIC;CCLE	22.404	Loss
CK1_CK1_CK1-D_CSNK1E_ST	P35222	CTNNB1	P49674	CSNK1E	S45	T41A	41	Missense	distal	-4	no	38.292	40.825	PhosphoSitePlus	TCGA;COSMIC;GDSC;CCLE	22.404	Up-regulation
CK1_CK1_CK1-D_CSNK1E_ST	P35222	CTNNB1	P49674	CSNK1E	S45	T41I	41	Missense	distal	-4	no	38.292	35.594	PhosphoSitePlus	TCGA;COSMIC	22.404	Down-regulation
CK1_CK1_CK1-D_CSNK1E_ST	P35222	CTNNB1	P49674	CSNK1E	S45	S45Y	45	Missense	central	0	yes	38.292	0.000	PhosphoSitePlus	TCGA;COSMIC	22.404	Loss
CK1_CK1_CK1-D_CSNK1E_ST	P35222	CTNNB1	P49674	CSNK1E	S45	T41N	41	Missense	distal	-4	no	38.292	34.399	PhosphoSitePlus	TCGA;COSMIC	22.404	Down-regulation
CK1_CK1_CK1-D_CSNK1E_ST	P35222	CTNNB1	P49674	CSNK1E	S45	S45C	45	Missense	central	0	yes	38.292	0.000	PhosphoSitePlus	TCGA;COSMIC;GDSC;CCLE	22.404	Loss
CK1_CK1_CK1-D_CSNK1E_ST	P35222	CTNNB1	P49674	CSNK1E	S250	I256M	256	Missense	distal	6	no	24.069	25.722	EPSD	TCGA;COSMIC	22.404	Up-regulation
CK1_CK1_CK1-D_CSNK1E_ST	P35222	CTNNB1	P49674	CSNK1E	S250	I256T	256	Missense	distal	6	no	24.069	23.084	EPSD	TCGA;COSMIC	22.404	Down-regulation
CK1_CK1_CK1-D_CSNK1E_ST	P35222	CTNNB1	P49674	CSNK1E	T393	E396D	396	Missense	distal	3	no	18.635	24.839	EPSD	TCGA	22.404	Gain
CK1_CK1_CK1-D_CSNK1E_ST	P35222	CTNNB1	P49674	CSNK1E	T556	M553V	553	Missense	distal	-3	no	23.473	21.489	EPSD	TCGA;COSMIC	22.404	Loss
CK1_CK1_CK1-D_CSNK1E_ST	Q13541	EIF4EBP1	P49674	CSNK1E	T50	R56Q	56	Missense	distal	6	no	32.732	31.667	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC;GDSC;CCLE	22.404	Down-regulation
CK1_CK1_CK1-D_CSNK1E_ST	Q13541	EIF4EBP1	P49674	CSNK1E	T50	R56W	56	Missense	distal	6	no	32.732	27.776	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	22.404	Down-regulation
CK1_CK1_CK1-D_CSNK1E_ST	Q13541	EIF4EBP1	P49674	CSNK1E	S83	S86N	86	Missense	distal	3	no	27.070	21.760	EPSD	TCGA;ICGC;COSMIC	22.404	Loss
CK1_CK1_CK1-D_CSNK1E_ST	Q13541	EIF4EBP1	P49674	CSNK1E	S86	S86N	86	Missense	central	0	yes	28.540	0.000	EPSD	TCGA;ICGC;COSMIC	22.404	Loss
CK1_CK1_CK1-D_CSNK1E_ST	Q9BZL6	PRKD2	P49674	CSNK1E	S225	R224H	224	Missense	proximal	-1	no	23.231	23.786	EPSD	TCGA;COSMIC	22.404	Up-regulation
CK1_CK1_CK1-D_CSNK1E_ST	Q9BZL6	PRKD2	P49674	CSNK1E	S225	E228K	228	Missense	distal	3	no	23.231	23.133	EPSD	TCGA;COSMIC;CCLE	22.404	Down-regulation
CK1_CK1_CK1-D_CSNK1E_ST	Q9BZL6	PRKD2	P49674	CSNK1E	S344	E345Q	345	Missense	proximal	1	no	22.484	21.995	EPSD	TCGA;COSMIC;CCLE	22.404	Loss
CK1_CK1_CK1-D_CSNK1E_ST	Q9BZL6	PRKD2	P49674	CSNK1E	S344	A339T	339	Missense	distal	-5	no	22.484	21.820	EPSD	TCGA;COSMIC	22.404	Loss
CK1_CK1_CK1-D_CSNK1E_ST	Q9BZL6	PRKD2	P49674	CSNK1E	S347	E345Q	345	Missense	proximal	-2	no	22.533	20.147	EPSD	TCGA;COSMIC;CCLE	22.404	Loss
CK1_CK1_CK1-D_CSNK1E_ST	Q9BZL6	PRKD2	P49674	CSNK1E	T714	A716T	716	Missense	proximal	2	no	27.170	25.343	EPSD	TCGA;COSMIC	22.404	Down-regulation
CK1_CK1_CK1-D_CSNK1E_ST	Q9BZL6	PRKD2	P49674	CSNK1E	T714	R709H	709	Missense	distal	-5	no	27.170	26.549	EPSD	TCGA;COSMIC	22.404	Down-regulation
CK1_CK1_CK1-D_CSNK1E_ST	Q9BZL6	PRKD2	P49674	CSNK1E	T714	P715S	715	Missense	proximal	1	no	27.170	27.466	EPSD	TCGA;COSMIC	22.404	Up-regulation
CK1_CK1_CK1-D_CSNK1E_ST	Q9BZL6	PRKD2	P49674	CSNK1E	T714	E721K	721	Missense	distal	7	no	27.170	27.525	EPSD	TCGA;COSMIC	22.404	Up-regulation
CK1_CK1_CK1-D_CSNK1E_ST	O60716	CTNND1	P49674	CSNK1E	T111	P117H	117	Missense	distal	6	no	24.169	21.474	EPSD	TCGA;COSMIC	22.404	Loss
CK1_CK1_CK1-D_CSNK1E_ST	O60716	CTNND1	P49674	CSNK1E	S168	L163W	163	Missense	distal	-5	no	25.621	24.940	EPSD	TCGA;COSMIC	22.404	Down-regulation
CK1_CK1_CK1-D_CSNK1E_ST	O60716	CTNND1	P49674	CSNK1E	S268	R264Q	264	Missense	distal	-4	no	44.781	46.532	PhosphoSitePlus	TCGA;COSMIC	22.404	Up-regulation
CK1_CK1_CK1-D_CSNK1E_ST	O60716	CTNND1	P49674	CSNK1E	S268	S269T	269	Missense	proximal	1	no	44.781	44.170	PhosphoSitePlus	TCGA	22.404	Down-regulation
CK1_CK1_CK1-D_CSNK1E_ST	O60716	CTNND1	P49674	CSNK1E	S268	V265I	265	Missense	distal	-3	no	44.781	47.257	PhosphoSitePlus	TCGA;COSMIC	22.404	Up-regulation
CK1_CK1_CK1-D_CSNK1E_ST	O60716	CTNND1	P49674	CSNK1E	S268	D271N	271	Missense	distal	3	no	44.781	38.687	PhosphoSitePlus	TCGA;COSMIC	22.404	Down-regulation
CK1_CK1_CK1-D_CSNK1E_ST	O60716	CTNND1	P49674	CSNK1E	S268	F275L	275	Missense	distal	7	no	44.781	44.637	PhosphoSitePlus	TCGA;COSMIC	22.404	Down-regulation
CK1_CK1_CK1-D_CSNK1E_ST	O60716	CTNND1	P49674	CSNK1E	S268	R274H	274	Missense	distal	6	no	44.781	42.549	PhosphoSitePlus	TCGA;COSMIC;GDSC;CCLE	22.404	Down-regulation
CK1_CK1_CK1-D_CSNK1E_ST	O60716	CTNND1	P49674	CSNK1E	S268	R264W	264	Missense	distal	-4	no	44.781	38.875	PhosphoSitePlus	TCGA;COSMIC	22.404	Down-regulation
CK1_CK1_CK1-D_CSNK1E_ST	O60716	CTNND1	P49674	CSNK1E	S268	V263I	263	Missense	distal	-5	no	44.781	44.383	PhosphoSitePlus	TCGA	22.404	Down-regulation
CK1_CK1_CK1-D_CSNK1E_ST	O60716	CTNND1	P49674	CSNK1E	S651	E657D	657	Missense	distal	6	no	19.964	23.594	EPSD	TCGA;COSMIC	22.404	Gain
CK1_CK1_CK1-D_CSNK1E_ST	O60716	CTNND1	P49674	CSNK1E	S943	L944V	944	Missense	proximal	1	no	23.434	23.769	EPSD	TCGA;COSMIC	22.404	Up-regulation
CK1_CK1_CK1-D_CSNK1E_ST	O60716	CTNND1	P49674	CSNK1E	S943	E939K	939	Missense	distal	-4	no	23.434	17.868	EPSD	TCGA;COSMIC	22.404	Loss
CK1_CK1_CK1-D_CSNK1E_ST	O60353	FZD6	P49674	CSNK1E	S624	E631K	631	Missense	distal	7	no	31.668	32.023	EPSD	TCGA;ICGC;COSMIC	22.404	Up-regulation
CK1_CK1_CK1-D_CSNK1E_ST	O60353	FZD6	P49674	CSNK1E	S624	S629F	629	Missense	distal	5	no	31.668	32.673	EPSD	TCGA;COSMIC	22.404	Up-regulation
CK1_CK1_CK1-D_CSNK1E_ST	O60353	FZD6	P49674	CSNK1E	S624	S626C	626	Missense	proximal	2	no	31.668	29.865	EPSD	TCGA;ICGC;COSMIC	22.404	Down-regulation
CK1_CK1_CK1-D_CSNK1E_ST	O60353	FZD6	P49674	CSNK1E	S624	G630V	630	Missense	distal	6	no	31.668	28.984	EPSD	TCGA;ICGC;COSMIC	22.404	Down-regulation
CK1_CK1_CK1-D_CSNK1E_ST	O60353	FZD6	P49674	CSNK1E	S624	A622V	622	Missense	proximal	-2	no	31.668	29.682	EPSD	TCGA;ICGC;COSMIC	22.404	Down-regulation
CK1_CK1_CK1-D_CSNK1E_ST	O60353	FZD6	P49674	CSNK1E	S624	I625V	625	Missense	proximal	1	no	31.668	31.381	EPSD	TCGA;ICGC	22.404	Down-regulation
CK1_CK1_CK1-D_CSNK1E_ST	O60353	FZD6	P49674	CSNK1E	S645	R647W	647	Missense	proximal	2	no	33.678	33.556	EPSD	TCGA;ICGC;COSMIC	22.404	Down-regulation
CK1_CK1_CK1-D_CSNK1E_ST	O60353	FZD6	P49674	CSNK1E	S648	R647W	647	Missense	proximal	-1	no	22.685	17.872	PhosphoSitePlus	TCGA;ICGC;COSMIC	22.404	Loss
CK1_CK1_CK1-D_CSNK1E_ST	O60353	FZD6	P49674	CSNK1E	S674	L669S	669	Missense	distal	-5	no	28.754	30.262	EPSD	TCGA;ICGC;COSMIC	22.404	Up-regulation
CK1_CK1_CK1-D_CSNK1E_ST	O60353	FZD6	P49674	CSNK1E	S674	S678N	678	Missense	distal	4	no	28.754	28.846	EPSD	TCGA	22.404	Up-regulation
CK1_CK1_CK1-D_CSNK1E_ST	O60353	FZD6	P49674	CSNK1E	S675	L669S	669	Missense	distal	-6	no	22.598	23.879	EPSD	TCGA;ICGC;COSMIC	22.404	Up-regulation
CK1_CK1_CK1-D_CSNK1E_ST	O60353	FZD6	P49674	CSNK1E	S675	S678N	678	Missense	distal	3	no	22.598	17.289	EPSD	TCGA	22.404	Loss
CAMK_CAMK1_CAMK1_ST	Q9UQL6	HDAC5	Q14012	CAMK1	T546	E551D	551	Missense	distal	5	no	36.489	35.174	EPSD	TCGA;ICGC;COSMIC	32.882	Down-regulation
CAMK_CAMK1_CAMK1_ST	P46527	CDKN1B	Q14012	CAMK1	S106	A103V	103	Missense	distal	-3	no	34.909	34.019	EPSD	TCGA;ICGC	32.882	Down-regulation
CAMK_CAMK1_CAMK1_ST	P46527	CDKN1B	Q14012	CAMK1	T157	S161C	161	Missense	distal	4	no	48.065	48.870	PhosphoSitePlus;EPSD	TCGA;ICGC;COSMIC	32.882	Up-regulation
CAMK_CAMK1_CAMK1_ST	P46527	CDKN1B	Q14012	CAMK1	T157	S161Y	161	Missense	distal	4	no	48.065	48.284	PhosphoSitePlus;EPSD	TCGA;ICGC	32.882	Up-regulation
CAMK_CAMK1_CAMK1_ST	P46527	CDKN1B	Q14012	CAMK1	T157	G150E	150	Missense	distal	-7	no	48.065	48.879	PhosphoSitePlus;EPSD	TCGA;ICGC;COSMIC	32.882	Up-regulation
CAMK_CAMK1_CAMK1_ST	Q9NP62	GCM1	Q14012	CAMK1	S47	K42Q	42	Missense	distal	-5	no	46.907	44.841	PhosphoSitePlus	TCGA	32.882	Down-regulation
CAMK_CAMK1_CAMK1_ST	Q9NP62	GCM1	Q14012	CAMK1	S47	H43L	43	Missense	distal	-4	no	46.907	45.385	PhosphoSitePlus	TCGA;ICGC;COSMIC	32.882	Down-regulation
CAMK_CAMK1_CAMK1_ST	Q9NP62	GCM1	Q14012	CAMK1	S47	R54W	54	Missense	distal	7	no	46.907	47.470	PhosphoSitePlus	TCGA;ICGC;COSMIC	32.882	Up-regulation
CAMK_CAMK1_CAMK1_ST	Q9NP62	GCM1	Q14012	CAMK1	S47	K42I	42	Missense	distal	-5	no	46.907	47.725	PhosphoSitePlus	TCGA;ICGC	32.882	Up-regulation
CAMK_CAMK1_CAMK1_ST	Q9NP62	GCM1	Q14012	CAMK1	T174	V179I	179	Missense	distal	5	no	42.288	42.652	EPSD	TCGA;ICGC;COSMIC	32.882	Up-regulation
CAMK_CAMK1_CAMK1_ST	Q9NP62	GCM1	Q14012	CAMK1	T174	K170E	170	Missense	distal	-4	no	42.288	39.930	EPSD	TCGA;ICGC	32.882	Down-regulation
CAMK_CAMK1_CAMK1_ST	Q9NP62	GCM1	Q14012	CAMK1	S269	S270N	270	Missense	proximal	1	no	39.497	36.056	EPSD	TCGA;ICGC;COSMIC	32.882	Down-regulation
CAMK_CAMK1_CAMK1_ST	Q9NP62	GCM1	Q14012	CAMK1	S269	S276G	276	Missense	distal	7	no	39.497	39.478	EPSD	TCGA;ICGC;COSMIC	32.882	Down-regulation
CAMK_CAMK1_CAMK1_ST	O43432	EIF4G3	Q14012	CAMK1	S536	A531T	531	Missense	distal	-5	no	29.718	34.746	EPSD	TCGA	32.882	Gain
CAMK_CAMK1_CAMK1_ST	P24844	MYL9	Q14012	CAMK1	T10	K7R	7	Missense	distal	-3	no	31.125	37.344	EPSD	TCGA;ICGC;COSMIC	32.882	Gain
CAMK_CAMK1_CAMK1_ST	P24844	MYL9	Q14012	CAMK1	T11	K7R	7	Missense	distal	-4	no	34.276	36.619	EPSD	TCGA;ICGC;COSMIC	32.882	Up-regulation
CAMK_CAMK1_CAMK1_ST	P24844	MYL9	Q14012	CAMK1	T11	T11I	11	Missense	central	0	yes	34.276	0.000	EPSD	TCGA;ICGC;COSMIC	32.882	Loss
CAMK_CAMK1_CAMK1_ST	P24844	MYL9	Q14012	CAMK1	T11	R17W	17	Missense	distal	6	no	34.276	33.583	EPSD	TCGA;ICGC;COSMIC	32.882	Down-regulation
CAMK_CAMK1_CAMK1_ST	P24844	MYL9	Q14012	CAMK1	T11	A6V	6	Missense	distal	-5	no	34.276	36.214	EPSD	TCGA;ICGC	32.882	Up-regulation
CAMK_CAMK1_CAMK1_ST	P24844	MYL9	Q14012	CAMK1	T19	R17W	17	Missense	proximal	-2	no	41.883	32.973	EPSD	TCGA;ICGC;COSMIC	32.882	Down-regulation
CAMK_CAMK1_CAMK1_ST	P24844	MYL9	Q14012	CAMK1	S20	R17W	17	Missense	distal	-3	no	50.791	34.729	PhosphoSitePlus	TCGA;ICGC;COSMIC	32.882	Down-regulation
CAMK_CAMK1_CAMK1_ST	P24844	MYL9	Q14012	CAMK1	T128	R133H	133	Missense	distal	5	no	39.643	37.944	EPSD	TCGA;COSMIC	32.882	Down-regulation
CAMK_CAMK1_CAMK1_ST	P24844	MYL9	Q14012	CAMK1	T128	M130V	130	Missense	proximal	2	no	39.643	40.081	EPSD	TCGA;ICGC;COSMIC;CCLE	32.882	Up-regulation
CAMK_CAMK1_CAMK1_ST	P24844	MYL9	Q14012	CAMK1	T128	D121A	121	Missense	distal	-7	no	39.643	39.756	EPSD	TCGA;ICGC;COSMIC	32.882	Up-regulation
CAMK_CAMK1_CAMK1_ST	P24844	MYL9	Q14012	CAMK1	T128	T129I	129	Missense	proximal	1	no	39.643	39.765	EPSD	TCGA;ICGC;COSMIC	32.882	Up-regulation
CAMK_CAMK1_CAMK1_ST	Q05469	LIPE	Q14012	CAMK1	S565	R566H	566	Missense	proximal	1	no	38.493	37.354	EPSD	TCGA;ICGC;COSMIC;GDSC;CCLE	32.882	Down-regulation
CAMK_CAMK1_CAMK1_ST	Q05469	LIPE	Q14012	CAMK1	S607	L610P	610	Missense	distal	3	no	34.844	34.840	EPSD	TCGA;ICGC;COSMIC	32.882	Down-regulation
CAMK_CAMK1_CAMK1_ST	Q05469	LIPE	Q14012	CAMK1	T813	R810Q	810	Missense	distal	-3	no	43.057	33.991	EPSD	TCGA;ICGC;COSMIC;GDSC	32.882	Down-regulation
CAMK_CAMK1_CAMK1_ST	Q05469	LIPE	Q14012	CAMK1	S855	E856K	856	Missense	proximal	1	no	51.500	44.472	PhosphoSitePlus	TCGA;ICGC;COSMIC	32.882	Down-regulation
CAMK_CAMK1_CAMK1_ST	Q05469	LIPE	Q14012	CAMK1	S855	P849L	849	Missense	distal	-6	no	51.500	50.807	PhosphoSitePlus	TCGA;ICGC;COSMIC	32.882	Down-regulation
CAMK_CAMK1_CAMK1_ST	Q05469	LIPE	Q14012	CAMK1	S855	R851C	851	Missense	distal	-4	no	51.500	44.095	PhosphoSitePlus	TCGA;ICGC;COSMIC	32.882	Down-regulation
CAMK_CAMK1_CAMK1_ST	Q05469	LIPE	Q14012	CAMK1	S855	R851H	851	Missense	distal	-4	no	51.500	47.609	PhosphoSitePlus	TCGA;ICGC;COSMIC	32.882	Down-regulation
CAMK_CAMK1_CAMK1_ST	Q05469	LIPE	Q14012	CAMK1	S951	R949C	949	Missense	proximal	-2	no	34.694	25.835	EPSD	TCGA;ICGC;COSMIC	32.882	Loss
CAMK_CAMK1_CAMK1_ST	Q9UQM7	CAMK2A	Q14012	CAMK1	T10	E17Q	17	Missense	distal	7	no	35.370	35.704	EPSD	TCGA;ICGC;COSMIC	32.882	Up-regulation
CAMK_CAMK1_CAMK1_ST	Q9UQM7	CAMK2A	Q14012	CAMK1	T10	F16L	16	Missense	distal	6	no	35.370	35.687	EPSD	TCGA;ICGC;COSMIC	32.882	Up-regulation
CAMK_CAMK1_CAMK1_ST	Q9UQM7	CAMK2A	Q14012	CAMK1	T10	E17D	17	Missense	distal	7	no	35.370	37.823	EPSD	TCGA;ICGC;COSMIC	32.882	Up-regulation
CAMK_CAMK1_CAMK1_ST	Q9UQM7	CAMK2A	Q14012	CAMK1	T10	E17K	17	Missense	distal	7	no	35.370	36.297	EPSD	TCGA;ICGC;COSMIC	32.882	Up-regulation
CAMK_CAMK1_CAMK1_ST	Q9UQM7	CAMK2A	Q14012	CAMK1	T261	R259H	259	Missense	proximal	-2	no	37.406	31.953	EPSD	TCGA;ICGC;COSMIC	32.882	Loss
CAMK_CAMK1_CAMK1_ST	Q9UQM7	CAMK2A	Q14012	CAMK1	T276	V277M	277	Missense	proximal	1	no	40.965	38.624	EPSD	TCGA;ICGC;COSMIC	32.882	Down-regulation
CAMK_CAMK1_CAMK1_ST	Q9UQM7	CAMK2A	Q14012	CAMK1	T276	S275Y	275	Missense	proximal	-1	no	40.965	40.945	EPSD	TCGA;ICGC;COSMIC	32.882	Down-regulation
CAMK_CAMK1_CAMK1_ST	Q9UQM7	CAMK2A	Q14012	CAMK1	T276	R274C	274	Missense	proximal	-2	no	40.965	32.106	EPSD	TCGA;ICGC	32.882	Loss
CAMK_CAMK1_CAMK1_ST	Q9UQM7	CAMK2A	Q14012	CAMK1	T286	V287M	287	Missense	proximal	1	no	42.306	39.965	EPSD	TCGA;ICGC;COSMIC	32.882	Down-regulation
CAMK_CAMK1_CAMK1_ST	Q9UQM7	CAMK2A	Q14012	CAMK1	S314	F313L	313	Missense	proximal	-1	no	40.259	40.308	EPSD	TCGA;ICGC;COSMIC	32.882	Up-regulation
CAMK_CAMK1_CAMK1_ST	Q9UQM7	CAMK2A	Q14012	CAMK1	S331	D325N	325	Missense	distal	-6	no	40.579	40.411	EPSD	TCGA;ICGC;COSMIC	32.882	Down-regulation
CAMK_CAMK1_CAMK1_ST	Q9Y570	PPME1	Q14012	CAMK1	S265	K270N	270	Missense	distal	5	no	33.108	30.107	EPSD	TCGA;ICGC;COSMIC	32.882	Loss
TK_Src_SrcA_YES1_Y	P09917	ALOX5	P07947	YES1	Y23	D19E	19	Missense	distal	-4	no	24.000	23.692	PhosphoSitePlus;EPSD	TCGA;ICGC;COSMIC	16.372	Down-regulation
TK_Src_SrcA_YES1_Y	P09917	ALOX5	P07947	YES1	Y23	A16T	16	Missense	distal	-7	no	24.000	23.969	PhosphoSitePlus;EPSD	TCGA;ICGC;COSMIC	16.372	Down-regulation
TK_Src_SrcA_YES1_Y	P09917	ALOX5	P07947	YES1	Y23	G28C	28	Missense	distal	5	no	24.000	23.348	PhosphoSitePlus;EPSD	TCGA;ICGC;COSMIC	16.372	Down-regulation
TK_Src_SrcA_YES1_Y	P09917	ALOX5	P07947	YES1	Y446	T445I	445	Missense	proximal	-1	no	20.656	20.209	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	16.372	Down-regulation
TK_Src_SrcA_YES1_Y	Q05397	PTK2	P07947	YES1	Y251	C257R	257	Missense	distal	6	no	15.154	17.927	EPSD	TCGA;ICGC;COSMIC	16.372	Gain
TK_Src_SrcA_YES1_Y	Q05397	PTK2	P07947	YES1	Y407	E403K	403	Missense	distal	-4	no	18.472	16.861	EPSD	TCGA;ICGC;COSMIC	16.372	Down-regulation
TK_Src_SrcA_YES1_Y	Q05397	PTK2	P07947	YES1	Y407	E404G	404	Missense	distal	-3	no	18.472	14.774	EPSD	TCGA;ICGC;COSMIC	16.372	Loss
TK_Src_SrcA_YES1_Y	Q05397	PTK2	P07947	YES1	Y861	I860M	860	Missense	proximal	-1	no	28.135	28.044	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	16.372	Down-regulation
TK_Src_SrcA_YES1_Y	Q05397	PTK2	P07947	YES1	Y861	P867S	867	Missense	distal	6	no	28.135	24.102	EPSD;PhosphoSitePlus	TCGA;ICGC	16.372	Down-regulation
TK_Src_SrcA_YES1_Y	Q05397	PTK2	P07947	YES1	Y861	H859R	859	Missense	proximal	-2	no	28.135	28.180	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	16.372	Up-regulation
TK_Src_SrcA_YES1_Y	P04626	ERBB2	P07947	YES1	Y923	E930K	930	Missense	distal	7	no	19.455	19.826	EPSD	TCGA;COSMIC	16.372	Up-regulation
TK_Src_SrcA_YES1_Y	P04626	ERBB2	P07947	YES1	Y923	M916I	916	Missense	distal	-7	no	19.455	19.454	EPSD	TCGA;COSMIC	16.372	Down-regulation
TK_Src_SrcA_YES1_Y	P04626	ERBB2	P07947	YES1	Y1005	R1006C	1006	Missense	proximal	1	no	17.646	16.180	EPSD	TCGA;COSMIC	16.372	Loss
TK_Src_SrcA_YES1_Y	P04626	ERBB2	P07947	YES1	Y1221	N1219S	1219	Missense	proximal	-2	no	22.614	22.586	EPSD	TCGA;COSMIC	16.372	Down-regulation
TK_Src_SrcA_YES1_Y	P04626	ERBB2	P07947	YES1	Y1221	S1214N	1214	Missense	distal	-7	no	22.614	22.612	EPSD	TCGA;COSMIC;CCLE	16.372	Down-regulation
TK_Src_SrcA_YES1_Y	P04626	ERBB2	P07947	YES1	Y1222	N1219S	1219	Missense	distal	-3	no	16.726	16.219	EPSD	TCGA;COSMIC	16.372	Loss
TK_Src_SrcA_YES1_Y	P04626	ERBB2	P07947	YES1	Y1248	E1244Q	1244	Missense	distal	-4	no	16.654	15.872	EPSD	TCGA;COSMIC	16.372	Loss
TK_Src_SrcA_YES1_Y	P04626	ERBB2	P07947	YES1	Y1248	E1247A	1247	Missense	proximal	-1	no	16.654	17.093	EPSD	TCGA;COSMIC	16.372	Up-regulation
TK_Src_SrcA_YES1_Y	P04626	ERBB2	P07947	YES1	Y1248	P1241H	1241	Missense	distal	-7	no	16.654	16.620	EPSD	TCGA;COSMIC	16.372	Down-regulation
TK_Src_SrcA_YES1_Y	Q969T9	WBP2	P07947	YES1	Y231	A228T	228	Missense	distal	-3	no	27.279	15.455	PhosphoSitePlus;EPSD	TCGA;COSMIC	16.372	Loss
TK_Src_SrcA_YES1_Y	Q969T9	WBP2	P07947	YES1	Y231	A224T	224	Missense	distal	-7	no	27.279	27.247	PhosphoSitePlus;EPSD	TCGA;ICGC;COSMIC	16.372	Down-regulation
TK_Src_SrcA_YES1_Y	P46527	CDKN1B	P07947	YES1	Y74	G72D	72	Missense	proximal	-2	no	31.675	31.684	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	16.372	Up-regulation
TK_Src_SrcA_YES1_Y	P46527	CDKN1B	P07947	YES1	Y74	K81R	81	Missense	distal	7	no	31.675	32.056	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	16.372	Up-regulation
TK_Src_SrcA_YES1_Y	P46527	CDKN1B	P07947	YES1	Y88	K81R	81	Missense	distal	-7	no	30.194	30.163	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	16.372	Down-regulation
TK_Src_SrcA_YES1_Y	P46527	CDKN1B	P07947	YES1	Y89	K96Q	96	Missense	distal	7	no	28.772	28.259	PhosphoSitePlus;EPSD	TCGA;ICGC;COSMIC	16.372	Down-regulation
TK_Src_SrcA_YES1_Y	Q16555	DPYSL2	P07947	YES1	Y479	S486N	486	Missense	distal	7	no	31.780	31.726	PhosphoSitePlus	TCGA	16.372	Down-regulation
TK_Src_SrcA_YES1_Y	Q16543	CDC37	P07947	YES1	Y298	P294S	294	Missense	distal	-4	no	29.701	29.736	PhosphoSitePlus	TCGA;ICGC;COSMIC	16.372	Up-regulation
TK_Src_SrcA_YES1_Y	P11802	CDK4	P07947	YES1	Y17	R24L	24	Missense	distal	7	no	28.759	26.418	PhosphoSitePlus	TCGA;ICGC;COSMIC	16.372	Down-regulation
TK_Src_SrcA_YES1_Y	P11802	CDK4	P07947	YES1	Y17	A23S	23	Missense	distal	6	no	28.759	25.270	PhosphoSitePlus	TCGA;ICGC;COSMIC	16.372	Down-regulation
TK_Src_SrcA_YES1_Y	P11802	CDK4	P07947	YES1	Y17	G15R	15	Missense	proximal	-2	no	28.759	28.761	PhosphoSitePlus	TCGA;ICGC;COSMIC	16.372	Up-regulation
TK_Src_SrcA_YES1_Y	P11802	CDK4	P07947	YES1	Y17	K22M	22	Missense	distal	5	no	28.759	27.139	PhosphoSitePlus	TCGA;ICGC;COSMIC	16.372	Down-regulation
TK_Src_SrcA_YES1_Y	P11802	CDK4	P07947	YES1	Y17	R24H	24	Missense	distal	7	no	28.759	26.607	PhosphoSitePlus	TCGA;ICGC;COSMIC;GDSC;CCLE	16.372	Down-regulation
TK_Src_SrcA_YES1_Y	P11802	CDK4	P07947	YES1	Y17	R24S	24	Missense	distal	7	no	28.759	27.703	PhosphoSitePlus	TCGA;ICGC;COSMIC	16.372	Down-regulation
TK_Src_SrcA_YES1_Y	P11802	CDK4	P07947	YES1	Y17	R24C	24	Missense	distal	7	no	28.759	27.072	PhosphoSitePlus	TCGA;ICGC;COSMIC;GDSC;CCLE	16.372	Down-regulation
TK_Src_SrcA_YES1_Y	P11802	CDK4	P07947	YES1	Y17	K22Q	22	Missense	distal	5	no	28.759	28.320	PhosphoSitePlus	TCGA;ICGC;COSMIC;GDSC;CCLE	16.372	Down-regulation
TK_Src_SrcA_YES1_Y	P11802	CDK4	P07947	YES1	Y165	R163K	163	Missense	proximal	-2	no	17.679	17.662	EPSD	TCGA;COSMIC	16.372	Down-regulation
Other_IKK_TBK1_ST	Q96FA3	PELI1	Q9UHD2	TBK1	S76	S78L	78	Missense	proximal	2	no	180.586	177.301	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	145.681	Down-regulation
Other_IKK_TBK1_ST	Q96FA3	PELI1	Q9UHD2	TBK1	S76	Y79H	79	Missense	distal	3	no	180.586	180.157	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	145.681	Down-regulation
Other_IKK_TBK1_ST	Q96FA3	PELI1	Q9UHD2	TBK1	S76	S70G	70	Missense	distal	-6	no	180.586	162.255	EPSD;PhosphoSitePlus	TCGA;ICGC	145.681	Down-regulation
Other_IKK_TBK1_ST	Q96FA3	PELI1	Q9UHD2	TBK1	T80	V87L	87	Missense	distal	7	no	178.443	178.385	PhosphoSitePlus;EPSD	TCGA;ICGC;COSMIC	145.681	Down-regulation
Other_IKK_TBK1_ST	Q96FA3	PELI1	Q9UHD2	TBK1	T80	S78L	78	Missense	proximal	-2	no	178.443	178.291	PhosphoSitePlus;EPSD	TCGA;ICGC;COSMIC	145.681	Down-regulation
Other_IKK_TBK1_ST	Q96FA3	PELI1	Q9UHD2	TBK1	T80	Y79H	79	Missense	proximal	-1	no	178.443	179.361	PhosphoSitePlus;EPSD	TCGA;ICGC;COSMIC	145.681	Up-regulation
Other_IKK_TBK1_ST	Q96FA3	PELI1	Q9UHD2	TBK1	T80	Q85H	85	Missense	distal	5	no	178.443	175.971	PhosphoSitePlus;EPSD	TCGA;ICGC;COSMIC	145.681	Down-regulation
Other_IKK_TBK1_ST	Q96FA3	PELI1	Q9UHD2	TBK1	S82	V87L	87	Missense	distal	5	no	154.905	153.068	EPSD	TCGA;ICGC;COSMIC	145.681	Down-regulation
Other_IKK_TBK1_ST	Q96FA3	PELI1	Q9UHD2	TBK1	S82	V89F	89	Missense	distal	7	no	154.905	154.964	EPSD	TCGA;ICGC;COSMIC	145.681	Up-regulation
Other_IKK_TBK1_ST	Q96FA3	PELI1	Q9UHD2	TBK1	S82	S78L	78	Missense	distal	-4	no	154.905	154.670	EPSD	TCGA;ICGC;COSMIC	145.681	Down-regulation
Other_IKK_TBK1_ST	Q96FA3	PELI1	Q9UHD2	TBK1	S82	Y79H	79	Missense	distal	-3	no	154.905	153.251	EPSD	TCGA;ICGC;COSMIC	145.681	Down-regulation
Other_IKK_TBK1_ST	Q96FA3	PELI1	Q9UHD2	TBK1	S82	Q85H	85	Missense	distal	3	no	154.905	155.630	EPSD	TCGA;ICGC;COSMIC	145.681	Up-regulation
Other_IKK_TBK1_ST	Q96FA3	PELI1	Q9UHD2	TBK1	T288	P283H	283	Missense	distal	-5	no	175.899	175.348	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	145.681	Down-regulation
Other_IKK_TBK1_ST	Q96FA3	PELI1	Q9UHD2	TBK1	S293	V299I	299	Missense	distal	6	no	183.079	176.478	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC;CCLE	145.681	Down-regulation
Other_IKK_TBK1_ST	Q13501	SQSTM1	Q9UHD2	TBK1	S182	R183H	183	Missense	proximal	1	no	146.626	138.431	EPSD	TCGA;ICGC	145.681	Loss
Other_IKK_TBK1_ST	Q13501	SQSTM1	Q9UHD2	TBK1	S182	L185F	185	Missense	distal	3	no	146.626	147.582	EPSD	TCGA	145.681	Up-regulation
Other_IKK_TBK1_ST	Q13501	SQSTM1	Q9UHD2	TBK1	S229	S229L	229	Missense	central	0	yes	146.836	0.000	EPSD	TCGA;COSMIC	145.681	Loss
Other_IKK_TBK1_ST	Q13501	SQSTM1	Q9UHD2	TBK1	S229	P228L	228	Missense	proximal	-1	no	146.836	146.433	EPSD	TCGA;COSMIC	145.681	Down-regulation
Other_IKK_TBK1_ST	Q13501	SQSTM1	Q9UHD2	TBK1	S266	S266R	266	Missense	central	0	yes	163.942	0.000	EPSD	TCGA;ICGC	145.681	Loss
Other_IKK_TBK1_ST	Q13501	SQSTM1	Q9UHD2	TBK1	S272	S277G	277	Missense	distal	5	no	160.990	157.386	EPSD	TCGA;ICGC;COSMIC	145.681	Down-regulation
Other_IKK_TBK1_ST	Q13501	SQSTM1	Q9UHD2	TBK1	S272	S276Y	276	Missense	distal	4	no	160.990	152.544	EPSD	TCGA;ICGC	145.681	Down-regulation
Other_IKK_TBK1_ST	Q13501	SQSTM1	Q9UHD2	TBK1	S272	S277I	277	Missense	distal	5	no	160.990	158.645	EPSD	TCGA;ICGC	145.681	Down-regulation
Other_IKK_TBK1_ST	Q13501	SQSTM1	Q9UHD2	TBK1	S272	S266R	266	Missense	distal	-6	no	160.990	156.466	EPSD	TCGA;ICGC	145.681	Down-regulation
Other_IKK_TBK1_ST	Q13501	SQSTM1	Q9UHD2	TBK1	S275	S277G	277	Missense	proximal	2	no	154.122	146.800	EPSD	TCGA;ICGC;COSMIC	145.681	Down-regulation
Other_IKK_TBK1_ST	Q13501	SQSTM1	Q9UHD2	TBK1	S275	S276Y	276	Missense	proximal	1	no	154.122	172.188	EPSD	TCGA;ICGC	145.681	Up-regulation
Other_IKK_TBK1_ST	Q13501	SQSTM1	Q9UHD2	TBK1	S275	S277I	277	Missense	proximal	2	no	154.122	147.491	EPSD	TCGA;ICGC	145.681	Down-regulation
Other_IKK_TBK1_ST	Q13501	SQSTM1	Q9UHD2	TBK1	S276	S277G	277	Missense	proximal	1	no	158.047	156.718	EPSD	TCGA;ICGC;COSMIC	145.681	Down-regulation
Other_IKK_TBK1_ST	Q13501	SQSTM1	Q9UHD2	TBK1	S276	S276Y	276	Missense	central	0	yes	158.047	0.000	EPSD	TCGA;ICGC	145.681	Loss
Other_IKK_TBK1_ST	Q13501	SQSTM1	Q9UHD2	TBK1	S276	S277I	277	Missense	proximal	1	no	158.047	171.424	EPSD	TCGA;ICGC	145.681	Up-regulation
Other_IKK_TBK1_ST	Q13501	SQSTM1	Q9UHD2	TBK1	S287	P293S	293	Missense	distal	6	no	140.969	145.849	EPSD	TCGA;ICGC;COSMIC	145.681	Gain
Other_IKK_TBK1_ST	Q13501	SQSTM1	Q9UHD2	TBK1	S355	P348L	348	Missense	distal	-7	no	155.173	155.765	EPSD	TCGA;COSMIC	145.681	Up-regulation
Other_IKK_TBK1_ST	Q13501	SQSTM1	Q9UHD2	TBK1	S365	L367V	367	Missense	proximal	2	no	156.094	158.623	EPSD	TCGA;COSMIC	145.681	Up-regulation
Other_IKK_TBK1_ST	Q13501	SQSTM1	Q9UHD2	TBK1	S365	S365C	365	Missense	central	0	yes	156.094	0.000	EPSD	TCGA	145.681	Loss
Other_IKK_TBK1_ST	Q13501	SQSTM1	Q9UHD2	TBK1	S366	L367V	367	Missense	proximal	1	no	155.023	131.060	EPSD	TCGA;COSMIC	145.681	Loss
Other_IKK_TBK1_ST	Q13501	SQSTM1	Q9UHD2	TBK1	S366	S365C	365	Missense	proximal	-1	no	155.023	156.449	EPSD	TCGA	145.681	Up-regulation
Other_IKK_TBK1_ST	Q13501	SQSTM1	Q9UHD2	TBK1	S403	S397F	397	Missense	distal	-6	no	177.440	165.681	PhosphoSitePlus	TCGA;COSMIC	145.681	Down-regulation
Other_IKK_TBK1_ST	Q96CV9	OPTN	Q9UHD2	TBK1	S162	N169S	169	Missense	distal	7	no	148.195	148.111	EPSD	TCGA	145.681	Down-regulation
Other_IKK_TBK1_ST	Q96CV9	OPTN	Q9UHD2	TBK1	S174	F178V	178	Missense	distal	4	no	134.519	147.699	EPSD	TCGA;ICGC;COSMIC	145.681	Gain
Other_IKK_TBK1_ST	Q96CV9	OPTN	Q9UHD2	TBK1	S177	A184S	184	Missense	distal	7	no	192.197	192.172	PhosphoSitePlus;EPSD	TCGA;ICGC;COSMIC	145.681	Down-regulation
Other_IKK_TBK1_ST	Q96CV9	OPTN	Q9UHD2	TBK1	S177	D176Y	176	Missense	proximal	-1	no	192.197	192.706	PhosphoSitePlus;EPSD	TCGA;ICGC;COSMIC	145.681	Up-regulation
Other_IKK_TBK1_ST	Q96CV9	OPTN	Q9UHD2	TBK1	S177	E175Q	175	Missense	proximal	-2	no	192.197	192.456	PhosphoSitePlus;EPSD	TCGA;ICGC;COSMIC	145.681	Up-regulation
Other_IKK_TBK1_ST	Q96CV9	OPTN	Q9UHD2	TBK1	S177	F178V	178	Missense	proximal	1	no	192.197	161.472	PhosphoSitePlus;EPSD	TCGA;ICGC;COSMIC	145.681	Down-regulation
Other_IKK_TBK1_ST	Q96CV9	OPTN	Q9UHD2	TBK1	S177	A184D	184	Missense	distal	7	no	192.197	192.175	PhosphoSitePlus;EPSD	TCGA;ICGC	145.681	Down-regulation
Other_IKK_TBK1_ST	Q96CV9	OPTN	Q9UHD2	TBK1	S308	E315K	315	Missense	distal	7	no	145.900	145.961	EPSD	TCGA;ICGC;COSMIC	145.681	Up-regulation
Other_IKK_TBK1_ST	Q96CV9	OPTN	Q9UHD2	TBK1	S308	E312K	312	Missense	distal	4	no	145.900	143.780	EPSD	TCGA;ICGC;COSMIC	145.681	Loss
Other_IKK_TBK1_ST	Q96CV9	OPTN	Q9UHD2	TBK1	S308	E315D	315	Missense	distal	7	no	145.900	145.876	EPSD	TCGA;ICGC;COSMIC	145.681	Down-regulation
Other_IKK_TBK1_ST	Q96CV9	OPTN	Q9UHD2	TBK1	S308	E312A	312	Missense	distal	4	no	145.900	149.466	EPSD	TCGA;ICGC;COSMIC	145.681	Up-regulation
Other_IKK_TBK1_ST	Q96CV9	OPTN	Q9UHD2	TBK1	S367	E371K	371	Missense	distal	4	no	146.093	143.973	EPSD	TCGA;COSMIC	145.681	Loss
Other_IKK_TBK1_ST	Q96CV9	OPTN	Q9UHD2	TBK1	S473	A480S	480	Missense	distal	7	no	174.328	174.302	EPSD;PhosphoSitePlus	TCGA;ICGC	145.681	Down-regulation
Other_IKK_TBK1_ST	Q96CV9	OPTN	Q9UHD2	TBK1	S513	G509R	509	Missense	distal	-4	no	179.077	178.873	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	145.681	Down-regulation
Other_IKK_TBK1_ST	P23443	RPS6KB1	Q9UHD2	TBK1	T250	H251Y	251	Missense	proximal	1	no	134.526	152.576	EPSD	TCGA;COSMIC	145.681	Gain
Other_IKK_TBK1_ST	P23443	RPS6KB1	Q9UHD2	TBK1	T252	H251Y	251	Missense	proximal	-1	no	145.889	144.971	EPSD	TCGA;COSMIC	145.681	Loss
Other_IKK_TBK1_ST	P23443	RPS6KB1	Q9UHD2	TBK1	T387	Q389E	389	Missense	proximal	2	no	159.307	161.148	EPSD	TCGA;COSMIC	145.681	Up-regulation
Other_IKK_TBK1_ST	P23443	RPS6KB1	Q9UHD2	TBK1	T390	Q389E	389	Missense	proximal	-1	no	158.953	159.409	EPSD	TCGA;COSMIC	145.681	Up-regulation
Other_IKK_TBK1_ST	Q8TEV9	SMCR8	Q9UHD2	TBK1	S402	E405K	405	Missense	distal	3	no	173.904	174.403	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC;CCLE	145.681	Up-regulation
Other_IKK_TBK1_ST	Q8TEV9	SMCR8	Q9UHD2	TBK1	S402	Q395K	395	Missense	distal	-7	no	173.904	172.939	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	145.681	Down-regulation
Other_IKK_TBK1_ST	Q8TEV9	SMCR8	Q9UHD2	TBK1	S402	P407S	407	Missense	distal	5	no	173.904	174.575	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	145.681	Up-regulation
Other_IKK_TBK1_ST	Q8TEV9	SMCR8	Q9UHD2	TBK1	S417	V411L	411	Missense	distal	-6	no	147.876	145.064	EPSD	TCGA;ICGC;COSMIC	145.681	Loss
Other_IKK_TBK1_ST	Q8TEV9	SMCR8	Q9UHD2	TBK1	S471	T477M	477	Missense	distal	6	no	165.570	171.568	EPSD	TCGA;ICGC;COSMIC	145.681	Up-regulation
Other_IKK_TBK1_ST	Q8TEV9	SMCR8	Q9UHD2	TBK1	S471	E478D	478	Missense	distal	7	no	165.570	165.546	EPSD	TCGA;ICGC	145.681	Down-regulation
Other_IKK_TBK1_ST	Q8TEV9	SMCR8	Q9UHD2	TBK1	T511	S516T	516	Missense	distal	5	no	147.255	146.297	EPSD	TCGA;ICGC;COSMIC	145.681	Down-regulation
Other_IKK_TBK1_ST	Q8TEV9	SMCR8	Q9UHD2	TBK1	T511	S513N	513	Missense	proximal	2	no	147.255	140.552	EPSD	TCGA;ICGC;COSMIC	145.681	Loss
Other_IKK_TBK1_ST	Q8TEV9	SMCR8	Q9UHD2	TBK1	T511	S516I	516	Missense	distal	5	no	147.255	144.910	EPSD	TCGA;ICGC	145.681	Loss
Other_IKK_TBK1_ST	Q8TEV9	SMCR8	Q9UHD2	TBK1	S513	S516T	516	Missense	distal	3	no	146.784	148.367	EPSD	TCGA;ICGC;COSMIC	145.681	Up-regulation
Other_IKK_TBK1_ST	Q8TEV9	SMCR8	Q9UHD2	TBK1	S513	S513N	513	Missense	central	0	yes	146.784	0.000	EPSD	TCGA;ICGC;COSMIC	145.681	Loss
Other_IKK_TBK1_ST	Q8TEV9	SMCR8	Q9UHD2	TBK1	S513	S516I	516	Missense	distal	3	no	146.784	147.733	EPSD	TCGA;ICGC	145.681	Up-regulation
Other_IKK_TBK1_ST	Q8TEV9	SMCR8	Q9UHD2	TBK1	S516	S513N	513	Missense	distal	-3	no	159.533	150.813	EPSD	TCGA;ICGC;COSMIC	145.681	Down-regulation
Other_IKK_TBK1_ST	Q8TEV9	SMCR8	Q9UHD2	TBK1	S516	S516I	516	Missense	central	0	yes	159.533	0.000	EPSD	TCGA;ICGC	145.681	Loss
Other_IKK_TBK1_ST	Q8TEV9	SMCR8	Q9UHD2	TBK1	S667	R661W	661	Missense	distal	-6	no	146.772	121.326	EPSD	TCGA;ICGC;COSMIC;CCLE	145.681	Loss
Other_IKK_TBK1_ST	Q8TEV9	SMCR8	Q9UHD2	TBK1	S667	K665E	665	Missense	proximal	-2	no	146.772	147.708	EPSD	TCGA;ICGC	145.681	Up-regulation
Other_IKK_TBK1_ST	Q8TEV9	SMCR8	Q9UHD2	TBK1	T796	R802C	802	Missense	distal	6	no	176.896	171.534	PhosphoSitePlus;EPSD	TCGA;ICGC;COSMIC	145.681	Down-regulation
Other_IKK_TBK1_ST	Q8TEV9	SMCR8	Q9UHD2	TBK1	S886	R883H	883	Missense	distal	-3	no	162.049	162.389	EPSD	TCGA;ICGC	145.681	Up-regulation
Other_IKK_TBK1_ST	Q8TEV9	SMCR8	Q9UHD2	TBK1	S886	M885V	885	Missense	proximal	-1	no	162.049	162.076	EPSD	TCGA;ICGC;COSMIC	145.681	Up-regulation
Other_IKK_TBK1_ST	Q8TEV9	SMCR8	Q9UHD2	TBK1	S886	R883C	883	Missense	distal	-3	no	162.049	158.664	EPSD	TCGA;ICGC;COSMIC	145.681	Down-regulation
Other_IKK_TBK1_ST	Q8TEV9	SMCR8	Q9UHD2	TBK1	S886	F887V	887	Missense	proximal	1	no	162.049	131.324	EPSD	TCGA;ICGC	145.681	Loss
Other_IKK_TBK1_ST	Q8TEV9	SMCR8	Q9UHD2	TBK1	S932	D928V	928	Missense	distal	-4	no	165.178	164.683	EPSD	TCGA;ICGC;COSMIC	145.681	Down-regulation
Other_IKK_TBK1_ST	Q8TEV9	SMCR8	Q9UHD2	TBK1	S932	S932I	932	Missense	central	0	yes	165.178	0.000	EPSD	TCGA;ICGC;COSMIC	145.681	Loss
Other_IKK_TBK1_ST	Q14653	IRF3	Q9UHD2	TBK1	S123	G129E	129	Missense	distal	6	no	141.209	148.930	EPSD	TCGA;COSMIC	145.681	Gain
Other_IKK_TBK1_ST	Q14653	IRF3	Q9UHD2	TBK1	S173	P170S	170	Missense	distal	-3	no	174.935	179.199	EPSD;PhosphoSitePlus	TCGA;COSMIC;CCLE	145.681	Up-regulation
Other_IKK_TBK1_ST	Q14653	IRF3	Q9UHD2	TBK1	S175	P170S	170	Missense	distal	-5	no	184.189	185.154	EPSD;PhosphoSitePlus	TCGA;COSMIC;CCLE	145.681	Up-regulation
Other_IKK_TBK1_ST	Q14653	IRF3	Q9UHD2	TBK1	T253	T253K	253	Missense	central	0	yes	153.950	0.000	EPSD	TCGA;COSMIC	145.681	Loss
Other_IKK_TBK1_ST	Q14653	IRF3	Q9UHD2	TBK1	S259	T253K	253	Missense	distal	-6	no	149.360	143.765	EPSD	TCGA;COSMIC	145.681	Loss
Other_IKK_TBK1_ST	Q14653	IRF3	Q9UHD2	TBK1	S259	V261A	261	Missense	proximal	2	no	149.360	148.146	EPSD	TCGA;COSMIC	145.681	Down-regulation
Other_IKK_TBK1_ST	Q01094	E2F1	Q9UHD2	TBK1	S341	P346L	346	Missense	distal	5	no	156.414	155.386	EPSD	TCGA;ICGC;COSMIC	145.681	Down-regulation
Other_IKK_TBK1_ST	Q01094	E2F1	Q9UHD2	TBK1	T344	P346L	346	Missense	proximal	2	no	154.924	157.799	EPSD	TCGA;ICGC;COSMIC	145.681	Up-regulation
Other_IKK_TBK1_ST	Q01094	E2F1	Q9UHD2	TBK1	S349	P346L	346	Missense	distal	-3	no	145.505	146.324	EPSD	TCGA;ICGC;COSMIC	145.681	Gain
Other_IKK_TBK1_ST	Q01094	E2F1	Q9UHD2	TBK1	S382	E389K	389	Missense	distal	7	no	150.970	151.030	EPSD	TCGA;ICGC;COSMIC	145.681	Up-regulation
Other_IKK_TBK1_ST	Q92985	IRF7	Q9UHD2	TBK1	S487	C494R	494	Missense	distal	7	no	149.138	149.096	EPSD	TCGA;COSMIC	145.681	Down-regulation
Other_IKK_TBK1_ST	P31749	AKT1	Q9UHD2	TBK1	T87	P93S	93	Missense	distal	6	no	145.011	149.891	EPSD	TCGA;ICGC;COSMIC	145.681	Gain
Other_IKK_TBK1_ST	P31749	AKT1	Q9UHD2	TBK1	T87	W80R	80	Missense	distal	-7	no	145.011	147.240	EPSD	TCGA;ICGC;COSMIC	145.681	Gain
Other_IKK_TBK1_ST	P31749	AKT1	Q9UHD2	TBK1	S122	E116K	116	Missense	distal	-6	no	162.113	159.336	EPSD	TCGA;ICGC;COSMIC	145.681	Down-regulation
Other_IKK_TBK1_ST	P31749	AKT1	Q9UHD2	TBK1	S122	R121W	121	Missense	proximal	-1	no	162.113	164.509	EPSD	TCGA;ICGC;COSMIC	145.681	Up-regulation
Other_IKK_TBK1_ST	P31749	AKT1	Q9UHD2	TBK1	T308	G311D	311	Missense	distal	3	no	166.338	166.559	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC;GDSC;CCLE	145.681	Up-regulation
Other_IKK_TBK1_ST	P31749	AKT1	Q9UHD2	TBK1	S473	S475L	475	Missense	proximal	2	no	176.752	173.467	PhosphoSitePlus;EPSD	TCGA;ICGC;COSMIC	145.681	Down-regulation
Other_IKK_TBK1_ST	P31749	AKT1	Q9UHD2	TBK1	S475	S475L	475	Missense	central	0	yes	156.921	0.000	EPSD	TCGA;ICGC;COSMIC	145.681	Loss
Other_IKK_TBK1_ST	P42226	STAT6	Q9UHD2	TBK1	S837	H838P	838	Missense	proximal	1	no	140.774	149.093	EPSD	TCGA;ICGC;COSMIC	145.681	Gain
Other_IKK_TBK1_ST	Q9UHD2	TBK1	Q9UHD2	TBK1	S172	E165Q	165	Missense	distal	-7	no	192.036	192.469	PhosphoSitePlus	TCGA;ICGC;COSMIC	145.681	Up-regulation
Other_IKK_TBK1_ST	Q9UHD2	TBK1	Q9UHD2	TBK1	S172	D167N	167	Missense	distal	-5	no	192.036	190.824	PhosphoSitePlus	TCGA;ICGC;COSMIC	145.681	Down-regulation
Other_IKK_TBK1_ST	Q9UHD2	TBK1	Q9UHD2	TBK1	S172	V171A	171	Missense	proximal	-1	no	192.036	192.334	PhosphoSitePlus	TCGA;ICGC	145.681	Up-regulation
Other_IKK_TBK1_ST	Q9UHD2	TBK1	Q9UHD2	TBK1	T176	D183Y	183	Missense	distal	7	no	158.077	158.126	EPSD	TCGA;ICGC;COSMIC	145.681	Up-regulation
Other_IKK_TBK1_ST	Q9UHD2	TBK1	Q9UHD2	TBK1	T176	V171A	171	Missense	distal	-5	no	158.077	157.447	EPSD	TCGA;ICGC	145.681	Down-regulation
Other_IKK_TBK1_ST	Q9UHD2	TBK1	Q9UHD2	TBK1	T333	E337K	337	Missense	distal	4	no	161.014	158.893	EPSD	TCGA;ICGC;COSMIC	145.681	Down-regulation
Other_IKK_TBK1_ST	Q9UHD2	TBK1	Q9UHD2	TBK1	T333	I326V	326	Missense	distal	-7	no	161.014	161.773	EPSD	TCGA;ICGC;COSMIC	145.681	Up-regulation
Other_IKK_TBK1_ST	Q9UHD2	TBK1	Q9UHD2	TBK1	T333	F335V	335	Missense	proximal	2	no	161.014	170.504	EPSD	TCGA;ICGC;COSMIC	145.681	Up-regulation
Other_IKK_TBK1_ST	Q9UHD2	TBK1	Q9UHD2	TBK1	S509	S510G	510	Missense	proximal	1	no	158.064	156.735	EPSD	TCGA;ICGC;COSMIC	145.681	Down-regulation
Other_IKK_TBK1_ST	Q9UHD2	TBK1	Q9UHD2	TBK1	S510	S510G	510	Missense	central	0	yes	161.396	0.000	EPSD	TCGA;ICGC;COSMIC	145.681	Loss
Other_IKK_TBK1_ST	Q9UHD2	TBK1	Q9UHD2	TBK1	S527	A533V	533	Missense	distal	6	no	157.770	159.589	EPSD	TCGA;ICGC;COSMIC	145.681	Up-regulation
Other_IKK_TBK1_ST	Q9UHD2	TBK1	Q9UHD2	TBK1	S527	D523H	523	Missense	distal	-4	no	157.770	156.958	EPSD	TCGA;ICGC;COSMIC	145.681	Down-regulation
Other_IKK_TBK1_ST	Q9UHD2	TBK1	Q9UHD2	TBK1	S716	D720Y	720	Missense	distal	4	no	166.161	161.581	EPSD	TCGA;ICGC;COSMIC	145.681	Down-regulation
Other_IKK_TBK1_ST	Q13568	IRF5	Q9UHD2	TBK1	S156	M153L	153	Missense	distal	-3	no	160.190	161.969	EPSD	TCGA;ICGC;COSMIC	145.681	Up-regulation
Other_IKK_TBK1_ST	Q13568	IRF5	Q9UHD2	TBK1	S156	S158N	158	Missense	proximal	2	no	160.190	153.487	EPSD	TCGA;ICGC;COSMIC	145.681	Down-regulation
Other_IKK_TBK1_ST	Q13568	IRF5	Q9UHD2	TBK1	S156	L157M	157	Missense	proximal	1	no	160.190	154.764	EPSD	TCGA;ICGC;COSMIC	145.681	Down-regulation
Other_IKK_TBK1_ST	Q13568	IRF5	Q9UHD2	TBK1	S158	M153L	153	Missense	distal	-5	no	182.527	182.602	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	145.681	Up-regulation
Other_IKK_TBK1_ST	Q13568	IRF5	Q9UHD2	TBK1	S158	S158N	158	Missense	central	0	yes	182.527	0.000	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	145.681	Loss
Other_IKK_TBK1_ST	Q13568	IRF5	Q9UHD2	TBK1	S158	L157M	157	Missense	proximal	-1	no	182.527	182.605	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	145.681	Up-regulation
Other_IKK_TBK1_ST	Q8IUC6	TICAM1	Q9UHD2	TBK1	S60	L64F	64	Missense	distal	4	no	158.797	150.972	EPSD	TCGA;ICGC;COSMIC	145.681	Down-regulation
Other_IKK_TBK1_ST	Q8IUC6	TICAM1	Q9UHD2	TBK1	S343	T341N	341	Missense	proximal	-2	no	146.451	145.631	EPSD	TCGA;ICGC;COSMIC	145.681	Loss
Other_IKK_TBK1_ST	Q8IUC6	TICAM1	Q9UHD2	TBK1	S343	C349W	349	Missense	distal	6	no	146.451	140.976	EPSD	TCGA;ICGC;COSMIC	145.681	Loss
Other_IKK_TBK1_ST	Q8IUC6	TICAM1	Q9UHD2	TBK1	S343	T342A	342	Missense	proximal	-1	no	146.451	146.667	EPSD	TCGA;ICGC;COSMIC	145.681	Up-regulation
Other_IKK_TBK1_ST	Q8IUC6	TICAM1	Q9UHD2	TBK1	S500	E493D	493	Missense	distal	-7	no	158.144	158.577	EPSD	TCGA;ICGC;COSMIC	145.681	Up-regulation
Other_IKK_TBK1_ST	Q8IUC6	TICAM1	Q9UHD2	TBK1	S500	E493K	493	Missense	distal	-7	no	158.144	157.612	EPSD	TCGA;ICGC;COSMIC	145.681	Down-regulation
Other_IKK_TBK1_ST	Q8IUC6	TICAM1	Q9UHD2	TBK1	S500	S505N	505	Missense	distal	5	no	158.144	155.360	EPSD	TCGA;ICGC;COSMIC	145.681	Down-regulation
Other_IKK_TBK1_ST	Q04206	RELA	Q9UHD2	TBK1	S45	E39K	39	Missense	distal	-6	no	150.604	147.827	EPSD	TCGA;ICGC;COSMIC	145.681	Down-regulation
Other_IKK_TBK1_ST	Q04206	RELA	Q9UHD2	TBK1	S45	E49K	49	Missense	distal	4	no	150.604	148.483	EPSD	TCGA;ICGC;COSMIC	145.681	Down-regulation
Other_IKK_TBK1_ST	Q04206	RELA	Q9UHD2	TBK1	S45	G44V	44	Missense	proximal	-1	no	150.604	149.479	EPSD	TCGA;ICGC;COSMIC	145.681	Down-regulation
Other_IKK_TBK1_ST	Q04206	RELA	Q9UHD2	TBK1	T254	P256S	256	Missense	proximal	2	no	143.782	149.942	EPSD	TCGA;ICGC;COSMIC	145.681	Gain
Other_IKK_TBK1_ST	Q04206	RELA	Q9UHD2	TBK1	T254	P256L	256	Missense	proximal	2	no	143.782	146.657	EPSD	TCGA;ICGC;COSMIC	145.681	Gain
Other_IKK_TBK1_ST	Q04206	RELA	Q9UHD2	TBK1	T254	R253W	253	Missense	proximal	-1	no	143.782	146.179	EPSD	TCGA;ICGC;COSMIC	145.681	Gain
Other_IKK_TBK1_ST	Q04206	RELA	Q9UHD2	TBK1	S261	P256S	256	Missense	distal	-5	no	152.743	153.708	EPSD	TCGA;ICGC;COSMIC	145.681	Up-regulation
Other_IKK_TBK1_ST	Q04206	RELA	Q9UHD2	TBK1	S261	P256L	256	Missense	distal	-5	no	152.743	153.841	EPSD	TCGA;ICGC;COSMIC	145.681	Up-regulation
Other_IKK_TBK1_ST	Q04206	RELA	Q9UHD2	TBK1	S261	A258V	258	Missense	distal	-3	no	152.743	153.635	EPSD	TCGA;ICGC;COSMIC	145.681	Up-regulation
Other_IKK_TBK1_ST	Q04206	RELA	Q9UHD2	TBK1	T305	F309L	309	Missense	distal	4	no	142.317	150.143	EPSD	TCGA;ICGC;COSMIC	145.681	Gain
Other_IKK_TBK1_ST	Q04206	RELA	Q9UHD2	TBK1	S319	G320E	320	Missense	proximal	1	no	158.507	154.141	EPSD	TCGA;ICGC;COSMIC	145.681	Down-regulation
Other_IKK_TBK1_ST	Q04206	RELA	Q9UHD2	TBK1	T322	G320E	320	Missense	proximal	-2	no	144.904	145.968	EPSD	TCGA;ICGC;COSMIC	145.681	Gain
Other_IKK_TBK1_ST	Q04206	RELA	Q9UHD2	TBK1	T435	E438V	438	Missense	distal	3	no	145.704	145.936	EPSD	TCGA;ICGC;COSMIC	145.681	Up-regulation
Other_IKK_TBK1_ST	Q04206	RELA	Q9UHD2	TBK1	T435	E438Q	438	Missense	distal	3	no	145.704	145.368	EPSD	TCGA;ICGC;COSMIC	145.681	Loss
Other_IKK_TBK1_ST	Q04206	RELA	Q9UHD2	TBK1	S468	V469I	469	Missense	proximal	1	no	132.336	154.272	EPSD	TCGA;ICGC;COSMIC	145.681	Gain
Other_IKK_TBK1_ST	Q04206	RELA	Q9UHD2	TBK1	S536	S529L	529	Missense	distal	-7	no	167.526	167.605	PhosphoSitePlus	TCGA;ICGC;COSMIC;GDSC;CCLE	145.681	Up-regulation
Other_IKK_TBK1_ST	Q7Z434	MAVS	Q9UHD2	TBK1	S94	T99I	99	Missense	distal	5	no	165.735	164.348	EPSD	TCGA;ICGC	145.681	Down-regulation
Other_IKK_TBK1_ST	Q7Z434	MAVS	Q9UHD2	TBK1	S94	E87K	87	Missense	distal	-7	no	165.735	165.203	EPSD	TCGA;ICGC	145.681	Down-regulation
Other_IKK_TBK1_ST	Q7Z434	MAVS	Q9UHD2	TBK1	S100	R102C	102	Missense	proximal	2	no	149.638	148.145	EPSD	TCGA;ICGC;COSMIC;CCLE	145.681	Down-regulation
Other_IKK_TBK1_ST	Q7Z434	MAVS	Q9UHD2	TBK1	S100	T99I	99	Missense	proximal	-1	no	149.638	150.052	EPSD	TCGA;ICGC	145.681	Up-regulation
Other_IKK_TBK1_ST	Q7Z434	MAVS	Q9UHD2	TBK1	S111	L112V	112	Missense	proximal	1	no	190.929	166.966	EPSD	TCGA;ICGC;COSMIC	145.681	Down-regulation
Other_IKK_TBK1_ST	Q7Z434	MAVS	Q9UHD2	TBK1	T163	P170S	170	Missense	distal	7	no	155.442	155.407	EPSD	TCGA;ICGC;COSMIC	145.681	Down-regulation
Other_IKK_TBK1_ST	Q7Z434	MAVS	Q9UHD2	TBK1	S217	S217F	217	Missense	central	0	yes	151.239	0.000	EPSD	TCGA;ICGC;COSMIC	145.681	Loss
Other_IKK_TBK1_ST	Q7Z434	MAVS	Q9UHD2	TBK1	S217	P223L	223	Missense	distal	6	no	151.239	153.707	EPSD	TCGA;ICGC;COSMIC	145.681	Up-regulation
Other_IKK_TBK1_ST	Q7Z434	MAVS	Q9UHD2	TBK1	T250	S256P	256	Missense	distal	6	no	154.502	149.622	EPSD	TCGA;ICGC;COSMIC	145.681	Down-regulation
Other_IKK_TBK1_ST	Q7Z434	MAVS	Q9UHD2	TBK1	S253	S256P	256	Missense	distal	3	no	149.579	151.229	EPSD	TCGA;ICGC;COSMIC	145.681	Up-regulation
Other_IKK_TBK1_ST	Q7Z434	MAVS	Q9UHD2	TBK1	S366	V372A	372	Missense	distal	6	no	157.086	155.267	EPSD	TCGA;ICGC;COSMIC	145.681	Down-regulation
Other_IKK_TBK1_ST	Q7Z434	MAVS	Q9UHD2	TBK1	T379	V372A	372	Missense	distal	-7	no	150.045	150.232	EPSD	TCGA;ICGC;COSMIC	145.681	Up-regulation
Other_IKK_TBK1_ST	Q7Z434	MAVS	Q9UHD2	TBK1	S383	A390G	390	Missense	distal	7	no	149.201	149.228	EPSD	TCGA;ICGC;COSMIC	145.681	Up-regulation
Other_IKK_TBK1_ST	Q7Z434	MAVS	Q9UHD2	TBK1	T388	A395T	395	Missense	distal	7	no	147.669	147.662	EPSD	TCGA;ICGC	145.681	Down-regulation
Other_IKK_TBK1_ST	Q7Z434	MAVS	Q9UHD2	TBK1	T388	A390G	390	Missense	proximal	2	no	147.669	142.317	EPSD	TCGA;ICGC;COSMIC	145.681	Loss
Other_IKK_TBK1_ST	Q7Z434	MAVS	Q9UHD2	TBK1	S401	D406H	406	Missense	distal	5	no	162.766	158.523	EPSD	TCGA;ICGC;COSMIC	145.681	Down-regulation
Other_IKK_TBK1_ST	Q7Z434	MAVS	Q9UHD2	TBK1	S401	A395T	395	Missense	distal	-6	no	162.766	163.761	EPSD	TCGA;ICGC	145.681	Up-regulation
Other_IKK_TBK1_ST	Q7Z434	MAVS	Q9UHD2	TBK1	S401	G396S	396	Missense	distal	-5	no	162.766	163.522	EPSD	TCGA;ICGC;COSMIC;GDSC	145.681	Up-regulation
Other_IKK_TBK1_ST	Q7Z434	MAVS	Q9UHD2	TBK1	S401	A397T	397	Missense	distal	-4	no	162.766	162.370	EPSD	TCGA;ICGC;COSMIC	145.681	Down-regulation
Other_IKK_TBK1_ST	Q7Z434	MAVS	Q9UHD2	TBK1	S402	G396S	396	Missense	distal	-6	no	135.352	153.683	EPSD	TCGA;ICGC;COSMIC;GDSC	145.681	Gain
Other_IKK_TBK1_ST	Q7Z434	MAVS	Q9UHD2	TBK1	S408	D406H	406	Missense	proximal	-2	no	157.020	156.092	EPSD	TCGA;ICGC;COSMIC	145.681	Down-regulation
Other_IKK_TBK1_ST	Q7Z434	MAVS	Q9UHD2	TBK1	S408	L414I	414	Missense	distal	6	no	157.020	156.008	EPSD	TCGA;ICGC;COSMIC	145.681	Down-regulation
Other_IKK_TBK1_ST	Q7Z434	MAVS	Q9UHD2	TBK1	S408	G413D	413	Missense	distal	5	no	157.020	162.093	EPSD	TCGA;ICGC;COSMIC	145.681	Up-regulation
Other_IKK_TBK1_ST	P30086	PEBP1	Q9UHD2	TBK1	S52	L58V	58	Missense	distal	6	no	146.491	152.080	EPSD	TCGA;ICGC;COSMIC	145.681	Up-regulation
Other_IKK_TBK1_ST	P30086	PEBP1	Q9UHD2	TBK1	S52	G57V	57	Missense	distal	5	no	146.491	150.232	EPSD	TCGA;ICGC;COSMIC	145.681	Up-regulation
Other_IKK_TBK1_ST	P30086	PEBP1	Q9UHD2	TBK1	S52	S54L	54	Missense	proximal	2	no	146.491	143.206	EPSD	TCGA;ICGC;COSMIC	145.681	Loss
Other_IKK_TBK1_ST	P30086	PEBP1	Q9UHD2	TBK1	S60	K62Q	62	Missense	proximal	2	no	153.647	153.699	EPSD	TCGA;ICGC;COSMIC	145.681	Up-regulation
Other_IKK_TBK1_ST	P30086	PEBP1	Q9UHD2	TBK1	S60	L58V	58	Missense	proximal	-2	no	153.647	151.884	EPSD	TCGA;ICGC;COSMIC	145.681	Down-regulation
Other_IKK_TBK1_ST	P30086	PEBP1	Q9UHD2	TBK1	S60	G57V	57	Missense	distal	-3	no	153.647	151.527	EPSD	TCGA;ICGC;COSMIC	145.681	Down-regulation
Other_IKK_TBK1_ST	P30086	PEBP1	Q9UHD2	TBK1	S60	S54L	54	Missense	distal	-6	no	153.647	142.231	EPSD	TCGA;ICGC;COSMIC	145.681	Loss
Other_IKK_TBK1_ST	P30086	PEBP1	Q9UHD2	TBK1	T65	K62Q	62	Missense	distal	-3	no	142.306	149.387	EPSD	TCGA;ICGC;COSMIC	145.681	Gain
Other_IKK_TBK1_ST	P30086	PEBP1	Q9UHD2	TBK1	S98	S104F	104	Missense	distal	6	no	145.978	134.646	EPSD	TCGA;ICGC;COSMIC	145.681	Loss
Other_IKK_TBK1_ST	P30086	PEBP1	Q9UHD2	TBK1	S98	M92T	92	Missense	distal	-6	no	145.978	151.152	EPSD	TCGA;ICGC;COSMIC	145.681	Up-regulation
Other_IKK_TBK1_ST	P30086	PEBP1	Q9UHD2	TBK1	S99	S104F	104	Missense	distal	5	no	158.633	155.052	EPSD	TCGA;ICGC;COSMIC	145.681	Down-regulation
Other_IKK_TBK1_ST	P30086	PEBP1	Q9UHD2	TBK1	S99	M92T	92	Missense	distal	-7	no	158.633	158.769	EPSD	TCGA;ICGC;COSMIC	145.681	Up-regulation
Other_IKK_TBK1_ST	P30086	PEBP1	Q9UHD2	TBK1	T101	G108D	108	Missense	distal	7	no	152.009	151.959	EPSD	TCGA;ICGC;COSMIC	145.681	Down-regulation
Other_IKK_TBK1_ST	P30086	PEBP1	Q9UHD2	TBK1	T101	G108C	108	Missense	distal	7	no	152.009	152.055	EPSD	TCGA;ICGC;COSMIC	145.681	Up-regulation
Other_IKK_TBK1_ST	P30086	PEBP1	Q9UHD2	TBK1	T101	S104F	104	Missense	distal	3	no	152.009	153.729	EPSD	TCGA;ICGC;COSMIC	145.681	Up-regulation
Other_IKK_TBK1_ST	P30086	PEBP1	Q9UHD2	TBK1	S109	S109L	109	Missense	central	0	yes	177.206	0.000	PhosphoSitePlus	TCGA;ICGC;COSMIC	145.681	Loss
Other_IKK_TBK1_ST	P30086	PEBP1	Q9UHD2	TBK1	S109	G108D	108	Missense	proximal	-1	no	177.206	175.924	PhosphoSitePlus	TCGA;ICGC;COSMIC	145.681	Down-regulation
Other_IKK_TBK1_ST	P30086	PEBP1	Q9UHD2	TBK1	S109	G108C	108	Missense	proximal	-1	no	177.206	177.402	PhosphoSitePlus	TCGA;ICGC;COSMIC	145.681	Up-regulation
Other_IKK_TBK1_ST	P30086	PEBP1	Q9UHD2	TBK1	S109	G110W	110	Missense	proximal	1	no	177.206	117.197	PhosphoSitePlus	TCGA;ICGC;COSMIC	145.681	Loss
Other_IKK_TBK1_ST	P30086	PEBP1	Q9UHD2	TBK1	S109	S104F	104	Missense	distal	-5	no	177.206	175.993	PhosphoSitePlus	TCGA;ICGC;COSMIC	145.681	Down-regulation
Other_IKK_TBK1_ST	P30086	PEBP1	Q9UHD2	TBK1	S109	G116D	116	Missense	distal	7	no	177.206	177.156	PhosphoSitePlus	TCGA;ICGC;COSMIC	145.681	Down-regulation
Other_IKK_TBK1_ST	P30086	PEBP1	Q9UHD2	TBK1	S153	G147V	147	Missense	distal	-6	no	158.653	168.378	EPSD	TCGA;ICGC;COSMIC	145.681	Up-regulation
Other_IKK_TBK1_ST	P03372	ESR1	Q9UHD2	TBK1	S305	I298M	298	Missense	distal	-7	no	183.655	184.612	PhosphoSitePlus	TCGA;ICGC;COSMIC	145.681	Up-regulation
Other_IKK_TBK1_ST	P03372	ESR1	Q9UHD2	TBK1	S305	A307S	307	Missense	proximal	2	no	183.655	185.625	PhosphoSitePlus	TCGA;ICGC;COSMIC	145.681	Up-regulation
Other_IKK_TBK1_ST	P03372	ESR1	Q9UHD2	TBK1	S305	T311M	311	Missense	distal	6	no	183.655	189.652	PhosphoSitePlus	TCGA;ICGC;COSMIC	145.681	Up-regulation
Other_IKK_TBK1_ST	P03372	ESR1	Q9UHD2	TBK1	S341	P336T	336	Missense	distal	-5	no	174.879	175.370	EPSD	TCGA;ICGC;COSMIC	145.681	Up-regulation
Other_IKK_TBK1_ST	P03372	ESR1	Q9UHD2	TBK1	S341	G344D	344	Missense	distal	3	no	174.879	175.101	EPSD	TCGA;ICGC;COSMIC	145.681	Up-regulation
Other_IKK_TBK1_ST	P03372	ESR1	Q9UHD2	TBK1	S554	R548H	548	Missense	distal	-6	no	155.372	153.835	EPSD	TCGA;ICGC;COSMIC	145.681	Down-regulation
Other_IKK_TBK1_ST	P03372	ESR1	Q9UHD2	TBK1	S554	R548C	548	Missense	distal	-6	no	155.372	147.046	EPSD	TCGA;ICGC;COSMIC;GDSC;CCLE	145.681	Down-regulation
Other_IKK_TBK1_ST	P03372	ESR1	Q9UHD2	TBK1	S554	A551E	551	Missense	distal	-3	no	155.372	153.768	EPSD	TCGA;ICGC;COSMIC	145.681	Down-regulation
Other_IKK_TBK1_ST	P03372	ESR1	Q9UHD2	TBK1	S554	A551V	551	Missense	distal	-3	no	155.372	156.264	EPSD	TCGA;ICGC;COSMIC;CCLE	145.681	Up-regulation
Other_IKK_TBK1_ST	P03372	ESR1	Q9UHD2	TBK1	S554	R555C	555	Missense	proximal	1	no	155.372	117.352	EPSD	TCGA;ICGC;COSMIC	145.681	Loss
Other_IKK_TBK1_ST	P03372	ESR1	Q9UHD2	TBK1	S554	R555H	555	Missense	proximal	1	no	155.372	147.177	EPSD	TCGA;ICGC;COSMIC;GDSC	145.681	Down-regulation
Other_IKK_TBK1_ST	P03372	ESR1	Q9UHD2	TBK1	S573	S575L	575	Missense	proximal	2	no	146.561	143.276	EPSD	TCGA;ICGC;COSMIC	145.681	Loss
Other_IKK_TBK1_ST	P03372	ESR1	Q9UHD2	TBK1	T574	S575L	575	Missense	proximal	1	no	134.608	150.012	EPSD	TCGA;ICGC;COSMIC	145.681	Gain
Other_IKK_TBK1_ST	P03372	ESR1	Q9UHD2	TBK1	S578	T585M	585	Missense	distal	7	no	159.592	159.573	EPSD	TCGA;ICGC;COSMIC	145.681	Down-regulation
Other_IKK_TBK1_ST	P03372	ESR1	Q9UHD2	TBK1	S578	S575L	575	Missense	distal	-3	no	159.592	156.147	EPSD	TCGA;ICGC;COSMIC	145.681	Down-regulation
Other_IKK_TBK1_ST	P03372	ESR1	Q9UHD2	TBK1	S578	K581T	581	Missense	distal	3	no	159.592	159.586	EPSD	TCGA;ICGC	145.681	Down-regulation
TK_Tie_TEK_Y	Q02763	TEK	Q02763	TEK	Y860	R867K	867	Missense	distal	7	no	2.860	2.870	EPSD	TCGA;COSMIC	0.993	Up-regulation
TK_Tie_TEK_Y	Q02763	TEK	Q02763	TEK	Y860	R856T	856	Missense	distal	-4	no	2.860	2.823	EPSD	TCGA;COSMIC	0.993	Down-regulation
TK_Tie_TEK_Y	Q02763	TEK	Q02763	TEK	Y860	K858E	858	Missense	proximal	-2	no	2.860	2.818	EPSD	TCGA	0.993	Down-regulation
TK_Tie_TEK_Y	Q02763	TEK	Q02763	TEK	Y860	K858T	858	Missense	proximal	-2	no	2.860	2.804	EPSD	TCGA	0.993	Down-regulation
TK_Tie_TEK_Y	Q02763	TEK	Q02763	TEK	Y992	G988C	988	Missense	distal	-4	no	3.019	3.004	PhosphoSitePlus;EPSD	TCGA;COSMIC	0.993	Down-regulation
TK_Tie_TEK_Y	Q02763	TEK	Q02763	TEK	Y1048	E1049K	1049	Missense	proximal	1	no	2.657	2.525	EPSD	TCGA;COSMIC	0.993	Down-regulation
TK_Tie_TEK_Y	Q02763	TEK	Q02763	TEK	Y1102	V1103M	1103	Missense	proximal	1	no	2.672	2.581	EPSD	TCGA;COSMIC;GDSC;CCLE	0.993	Down-regulation
TK_Tie_TEK_Y	Q02763	TEK	Q02763	TEK	Y1102	T1106M	1106	Missense	distal	4	no	2.672	2.346	EPSD	TCGA;COSMIC	0.993	Down-regulation
TK_Tie_TEK_Y	Q02763	TEK	Q02763	TEK	Y1102	R1099Q	1099	Missense	distal	-3	no	2.672	2.680	EPSD	TCGA;COSMIC	0.993	Up-regulation
TK_Tie_TEK_Y	Q02763	TEK	Q02763	TEK	Y1102	L1107F	1107	Missense	distal	5	no	2.672	2.752	EPSD	TCGA;COSMIC	0.993	Up-regulation
TK_Tie_TEK_Y	Q02763	TEK	Q02763	TEK	Y1108	V1103M	1103	Missense	distal	-5	no	2.631	2.644	EPSD;PhosphoSitePlus	TCGA;COSMIC;GDSC;CCLE	0.993	Up-regulation
TK_Tie_TEK_Y	Q02763	TEK	Q02763	TEK	Y1108	T1106M	1106	Missense	proximal	-2	no	2.631	2.587	EPSD;PhosphoSitePlus	TCGA;COSMIC	0.993	Down-regulation
TK_Tie_TEK_Y	Q02763	TEK	Q02763	TEK	Y1108	G1115E	1115	Missense	distal	7	no	2.631	2.623	EPSD;PhosphoSitePlus	TCGA;COSMIC	0.993	Down-regulation
TK_Tie_TEK_Y	Q02763	TEK	Q02763	TEK	Y1108	L1107F	1107	Missense	proximal	-1	no	2.631	2.370	EPSD;PhosphoSitePlus	TCGA;COSMIC	0.993	Down-regulation
TK_Tie_TEK_Y	Q02763	TEK	Q02763	TEK	Y1113	T1106M	1106	Missense	distal	-7	no	2.428	2.414	EPSD	TCGA;COSMIC	0.993	Down-regulation
TK_Tie_TEK_Y	Q02763	TEK	Q02763	TEK	Y1113	G1115E	1115	Missense	proximal	2	no	2.428	2.147	EPSD	TCGA;COSMIC	0.993	Down-regulation
TK_Tie_TEK_Y	Q02763	TEK	Q02763	TEK	Y1113	L1107F	1107	Missense	distal	-6	no	2.428	2.172	EPSD	TCGA;COSMIC	0.993	Down-regulation
CAMK_PKD_PRKD3_ST	Q9UQL6	HDAC5	O94806	PRKD3	S7	P4S	4	Missense	distal	-3	no	2.665	2.646	EPSD	TCGA;ICGC;COSMIC	1.136	Down-regulation
CAMK_PKD_PRKD3_ST	Q9UQL6	HDAC5	O94806	PRKD3	T199	L192F	192	Missense	distal	-7	no	2.172	2.322	EPSD	TCGA;ICGC;COSMIC	1.136	Up-regulation
CAMK_PKD_PRKD3_ST	Q15139	PRKD1	O94806	PRKD3	S218	S223C	223	Missense	distal	5	no	1.586	1.588	EPSD	TCGA;ICGC;COSMIC	1.136	Up-regulation
CAMK_PKD_PRKD3_ST	Q15139	PRKD1	O94806	PRKD3	S218	R216C	216	Missense	proximal	-2	no	1.586	1.489	EPSD	TCGA;ICGC;COSMIC	1.136	Down-regulation
CAMK_PKD_PRKD3_ST	Q15139	PRKD1	O94806	PRKD3	S218	S213T	213	Missense	distal	-5	no	1.586	1.823	EPSD	TCGA;ICGC;COSMIC	1.136	Up-regulation
CAMK_PKD_PRKD3_ST	Q15139	PRKD1	O94806	PRKD3	S218	V212A	212	Missense	distal	-6	no	1.586	1.616	EPSD	TCGA;ICGC	1.136	Up-regulation
CAMK_PKD_PRKD3_ST	Q15139	PRKD1	O94806	PRKD3	S218	V212I	212	Missense	distal	-6	no	1.586	1.559	EPSD	TCGA;ICGC;COSMIC	1.136	Down-regulation
CAMK_PKD_PRKD3_ST	Q15139	PRKD1	O94806	PRKD3	S412	K414N	414	Missense	proximal	2	no	2.536	2.530	EPSD	TCGA	1.136	Down-regulation
CAMK_PKD_PRKD3_ST	Q15139	PRKD1	O94806	PRKD3	S412	L406I	406	Missense	distal	-6	no	2.536	2.593	EPSD	TCGA;COSMIC	1.136	Up-regulation
CAMK_PKD_PRKD3_ST	Q15139	PRKD1	O94806	PRKD3	S549	P545L	545	Missense	distal	-4	no	2.374	2.401	EPSD	TCGA;COSMIC	1.136	Up-regulation
CAMK_PKD_PRKD3_ST	Q15139	PRKD1	O94806	PRKD3	S549	G551C	551	Missense	proximal	2	no	2.374	2.373	EPSD	TCGA;COSMIC	1.136	Down-regulation
CAMK_PKD_PRKD3_ST	Q15139	PRKD1	O94806	PRKD3	S738	R740Q	740	Missense	proximal	2	no	5.753	5.779	PhosphoSitePlus;EPSD	TCGA;ICGC;COSMIC	1.136	Up-regulation
CAMK_PKD_PRKD3_ST	Q15139	PRKD1	O94806	PRKD3	S738	R732Q	732	Missense	distal	-6	no	5.753	5.764	PhosphoSitePlus;EPSD	TCGA;COSMIC	1.136	Up-regulation
CAMK_PKD_PRKD3_ST	Q15139	PRKD1	O94806	PRKD3	S738	R732L	732	Missense	distal	-6	no	5.753	5.698	PhosphoSitePlus;EPSD	TCGA;COSMIC	1.136	Down-regulation
CAMK_PKD_PRKD3_ST	Q15139	PRKD1	O94806	PRKD3	S738	R732W	732	Missense	distal	-6	no	5.753	5.766	PhosphoSitePlus;EPSD	TCGA;COSMIC	1.136	Up-regulation
CAMK_PKD_PRKD3_ST	Q15139	PRKD1	O94806	PRKD3	S742	R740Q	740	Missense	proximal	-2	no	6.201	6.197	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	1.136	Down-regulation
CAMK_PKD_PRKD3_ST	Q15139	PRKD1	O94806	PRKD3	S742	A748S	748	Missense	distal	6	no	6.201	6.132	EPSD;PhosphoSitePlus	TCGA;COSMIC	1.136	Down-regulation
CAMK_PKD_PRKD3_ST	Q15139	PRKD1	O94806	PRKD3	S742	T746A	746	Missense	distal	4	no	6.201	6.181	EPSD;PhosphoSitePlus	TCGA	1.136	Down-regulation
CAMK_PKD_PRKD3_ST	Q9Y2X7	GIT1	O94806	PRKD3	S25	R26S	26	Missense	proximal	1	no	1.575	1.640	EPSD	TCGA;ICGC;COSMIC	1.136	Up-regulation
CAMK_PKD_PRKD3_ST	Q9Y2X7	GIT1	O94806	PRKD3	S25	P19H	19	Missense	distal	-6	no	1.575	1.563	EPSD	TCGA;ICGC	1.136	Down-regulation
CAMK_PKD_PRKD3_ST	Q9Y2X7	GIT1	O94806	PRKD3	S46	R52H	52	Missense	distal	6	no	5.616	5.586	PhosphoSitePlus	TCGA;ICGC	1.136	Down-regulation
CAMK_PKD_PRKD3_ST	Q9Y2X7	GIT1	O94806	PRKD3	S46	R39Q	39	Missense	distal	-7	no	5.616	5.459	PhosphoSitePlus	TCGA;ICGC;COSMIC	1.136	Down-regulation
CAMK_PKD_PRKD3_ST	Q9Y2X7	GIT1	O94806	PRKD3	S54	R52H	52	Missense	proximal	-2	no	2.494	2.426	EPSD	TCGA;ICGC	1.136	Down-regulation
CAMK_PKD_PRKD3_ST	Q9Y2X7	GIT1	O94806	PRKD3	S54	L61M	61	Missense	distal	7	no	2.494	2.517	EPSD	TCGA;ICGC	1.136	Up-regulation
CAMK_PKD_PRKD3_ST	Q9Y2X7	GIT1	O94806	PRKD3	T307	N301K	301	Missense	distal	-6	no	1.729	1.780	EPSD	TCGA;COSMIC	1.136	Up-regulation
AGC_PKC_PKCa_PRKCB_ST	P10636	MAPT	P05771-2	PRKCB	S171	R168H	168	Missense	distal	-3	no	2.924	-0.062	EPSD	TCGA;ICGC;COSMIC	0.942	Loss
AGC_PKC_PKCa_PRKCB_ST	P10636	MAPT	P05771-2	PRKCB	S171	R168C	168	Missense	distal	-3	no	2.924	-0.975	EPSD	TCGA;ICGC;COSMIC	0.942	Loss
AGC_PKC_PKCa_PRKCB_ST	P10636	MAPT	P05771-2	PRKCB	S214	P212L	212	Missense	proximal	-2	no	1.656	0.968	EPSD	TCGA;ICGC;COSMIC	0.942	Down-regulation
AGC_PKC_PKCa_PRKCB_ST	P10636	MAPT	P05771-2	PRKCB	S214	E220K	220	Missense	distal	6	no	1.656	2.152	EPSD	TCGA;ICGC;COSMIC	0.942	Up-regulation
AGC_PKC_PKCa_PRKCB_ST	P10636	MAPT	P05771-2	PRKCB	S355	E348V	348	Missense	distal	-7	no	3.476	3.593	EPSD	TCGA;ICGC;COSMIC	0.942	Up-regulation
AGC_PKC_PKCa_PRKCB_ST	P10636	MAPT	P05771-2	PRKCB	S355	D350G	350	Missense	distal	-5	no	3.476	3.360	EPSD	TCGA;ICGC;COSMIC	0.942	Down-regulation
AGC_PKC_PKCa_PRKCB_ST	P10636	MAPT	P05771-2	PRKCB	S369	Q373R	373	Missense	distal	4	no	3.530	4.150	EPSD	TCGA;ICGC;COSMIC	0.942	Up-regulation
AGC_PKC_PKCa_PRKCB_ST	P10636	MAPT	P05771-2	PRKCB	S369	K366E	366	Missense	distal	-3	no	3.530	0.195	EPSD	TCGA;ICGC;COSMIC	0.942	Loss
AGC_PKC_PKCa_PRKCB_ST	P10636	MAPT	P05771-2	PRKCB	S438	P436T	436	Missense	proximal	-2	no	1.209	1.654	EPSD	TCGA;ICGC;COSMIC	0.942	Up-regulation
AGC_PKC_PKCa_PRKCB_ST	P10636	MAPT	P05771-2	PRKCB	S438	P436L	436	Missense	proximal	-2	no	1.209	0.521	EPSD	TCGA;ICGC;COSMIC	0.942	Loss
AGC_PKC_PKCa_PRKCB_ST	P10636	MAPT	P05771-2	PRKCB	S438	K440E	440	Missense	proximal	2	no	1.209	-4.205	EPSD	TCGA;ICGC;COSMIC	0.942	Loss
AGC_PKC_PKCa_PRKCB_ST	P10636	MAPT	P05771-2	PRKCB	S438	S443F	443	Missense	distal	5	no	1.209	1.165	EPSD	TCGA;ICGC;COSMIC	0.942	Down-regulation
AGC_PKC_PKCa_PRKCB_ST	P10636	MAPT	P05771-2	PRKCB	S438	V431L	431	Missense	distal	-7	no	1.209	1.197	EPSD	TCGA;ICGC;COSMIC	0.942	Down-regulation
AGC_PKC_PKCa_PRKCB_ST	P10636	MAPT	P05771-2	PRKCB	S438	S444F	444	Missense	distal	6	no	1.209	0.792	EPSD	TCGA;ICGC	0.942	Loss
AGC_PKC_PKCa_PRKCB_ST	P10636	MAPT	P05771-2	PRKCB	T470	R472Q	472	Missense	proximal	2	no	3.997	-2.552	EPSD	TCGA	0.942	Loss
AGC_PKC_PKCa_PRKCB_ST	P10636	MAPT	P05771-2	PRKCB	T470	R472W	472	Missense	proximal	2	no	3.997	-5.517	EPSD	TCGA;COSMIC	0.942	Loss
AGC_PKC_PKCa_PRKCB_ST	P05107	ITGB2	P05771-2	PRKCB	T118	A112S	112	Missense	distal	-6	no	4.279	4.356	EPSD	TCGA;ICGC;COSMIC	0.942	Up-regulation
AGC_PKC_PKCa_PRKCB_ST	P05107	ITGB2	P05771-2	PRKCB	T118	R121Q	121	Missense	distal	3	no	4.279	3.714	EPSD	TCGA;ICGC;COSMIC	0.942	Down-regulation
AGC_PKC_PKCa_PRKCB_ST	P05107	ITGB2	P05771-2	PRKCB	T118	R121W	121	Missense	distal	3	no	4.279	2.927	EPSD	TCGA;ICGC;COSMIC	0.942	Down-regulation
AGC_PKC_PKCa_PRKCB_ST	P05107	ITGB2	P05771-2	PRKCB	T118	R120W	120	Missense	proximal	2	no	4.279	-5.235	EPSD	TCGA;ICGC	0.942	Loss
AGC_PKC_PKCa_PRKCB_ST	P05107	ITGB2	P05771-2	PRKCB	S496	D500G	500	Missense	distal	4	no	3.467	3.054	EPSD	TCGA;ICGC;COSMIC	0.942	Down-regulation
AGC_PKC_PKCa_PRKCB_ST	P05107	ITGB2	P05771-2	PRKCB	S496	R498Q	498	Missense	proximal	2	no	3.467	-3.081	EPSD	TCGA;ICGC;COSMIC	0.942	Loss
AGC_PKC_PKCa_PRKCB_ST	P05107	ITGB2	P05771-2	PRKCB	S496	G495R	495	Missense	proximal	-1	no	3.467	4.000	EPSD	TCGA;ICGC;COSMIC	0.942	Up-regulation
AGC_PKC_PKCa_PRKCB_ST	P05107	ITGB2	P05771-2	PRKCB	S591	R587C	587	Missense	distal	-4	no	5.199	5.705	EPSD	TCGA;ICGC;COSMIC	0.942	Up-regulation
AGC_PKC_PKCa_PRKCB_ST	P05107	ITGB2	P05771-2	PRKCB	S591	R586Q	586	Missense	distal	-5	no	5.199	5.182	EPSD	TCGA;ICGC;COSMIC	0.942	Down-regulation
AGC_PKC_PKCa_PRKCB_ST	P05107	ITGB2	P05771-2	PRKCB	S591	G594D	594	Missense	distal	3	no	5.199	5.569	EPSD	TCGA;ICGC;COSMIC	0.942	Up-regulation
AGC_PKC_PKCa_PRKCB_ST	P05107	ITGB2	P05771-2	PRKCB	S591	R597H	597	Missense	distal	6	no	5.199	4.439	EPSD	TCGA;ICGC;COSMIC	0.942	Down-regulation
AGC_PKC_PKCa_PRKCB_ST	P05107	ITGB2	P05771-2	PRKCB	S745	L743R	743	Missense	proximal	-2	no	0.240	2.760	PhosphoSitePlus;EPSD	TCGA;ICGC;COSMIC	0.942	Gain
AGC_PKC_PKCa_PRKCB_ST	P05107	ITGB2	P05771-2	PRKCB	S745	W747L	747	Missense	proximal	2	no	0.240	3.122	PhosphoSitePlus;EPSD	TCGA;ICGC;COSMIC	0.942	Gain
AGC_PKC_PKCa_PRKCB_ST	P98082	DAB2	P05771-2	PRKCB	S24	K21E	21	Missense	distal	-3	no	12.413	9.078	PhosphoSitePlus	TCGA;ICGC;COSMIC	0.942	Down-regulation
AGC_PKC_PKCa_PRKCB_ST	P98082	DAB2	P05771-2	PRKCB	S24	A18G	18	Missense	distal	-6	no	12.413	12.351	PhosphoSitePlus	TCGA;ICGC;COSMIC	0.942	Down-regulation
AGC_PKC_PKCa_PRKCB_ST	P98082	DAB2	P05771-2	PRKCB	S24	A22T	22	Missense	proximal	-2	no	12.413	12.818	PhosphoSitePlus	TCGA;ICGC;COSMIC	0.942	Up-regulation
AGC_PKC_PKCa_PRKCB_ST	P98082	DAB2	P05771-2	PRKCB	S24	A18V	18	Missense	distal	-6	no	12.413	12.479	PhosphoSitePlus	TCGA;ICGC;COSMIC	0.942	Up-regulation
AGC_PKC_PKCa_PRKCB_ST	P98082	DAB2	P05771-2	PRKCB	S24	K29N	29	Missense	distal	5	no	12.413	12.039	PhosphoSitePlus	TCGA;ICGC;COSMIC	0.942	Down-regulation
AGC_PKC_PKCa_PRKCB_ST	P98082	DAB2	P05771-2	PRKCB	S249	L250S	250	Missense	proximal	1	no	4.764	3.424	EPSD	TCGA;ICGC	0.942	Down-regulation
AGC_PKC_PKCa_PRKCB_ST	P98082	DAB2	P05771-2	PRKCB	S249	D244N	244	Missense	distal	-5	no	4.764	4.697	EPSD	TCGA;ICGC;COSMIC	0.942	Down-regulation
AGC_PKC_PKCa_PRKCB_ST	P98082	DAB2	P05771-2	PRKCB	S249	E242G	242	Missense	distal	-7	no	4.764	4.956	EPSD	TCGA	0.942	Up-regulation
AGC_PKC_PKCa_PRKCB_ST	P98082	DAB2	P05771-2	PRKCB	S313	S313C	313	Missense	central	0	yes	1.710	0.000	EPSD	TCGA;ICGC;COSMIC	0.942	Loss
AGC_PKC_PKCa_PRKCB_ST	P98082	DAB2	P05771-2	PRKCB	S313	S313Y	313	Missense	central	0	yes	1.710	0.000	EPSD	TCGA;ICGC;COSMIC	0.942	Loss
AGC_PKC_PKCa_PRKCB_ST	P98082	DAB2	P05771-2	PRKCB	S313	S313F	313	Missense	central	0	yes	1.710	0.000	EPSD	TCGA;ICGC;COSMIC	0.942	Loss
AGC_PKC_PKCa_PRKCB_ST	P98082	DAB2	P05771-2	PRKCB	S313	S316Y	316	Missense	distal	3	no	1.710	1.696	EPSD	TCGA;ICGC	0.942	Down-regulation
AGC_PKC_PKCa_PRKCB_ST	P98082	DAB2	P05771-2	PRKCB	S390	K392R	392	Missense	proximal	2	no	3.515	5.138	EPSD	TCGA;ICGC;COSMIC	0.942	Up-regulation
AGC_PKC_PKCa_PRKCB_ST	P98082	DAB2	P05771-2	PRKCB	S390	S390C	390	Missense	central	0	yes	3.515	0.000	EPSD	TCGA;ICGC;COSMIC	0.942	Loss
AGC_PKC_PKCa_PRKCB_ST	P98082	DAB2	P05771-2	PRKCB	S390	Q386H	386	Missense	distal	-4	no	3.515	3.700	EPSD	TCGA;ICGC;COSMIC	0.942	Up-regulation
AGC_PKC_PKCa_PRKCB_ST	P98082	DAB2	P05771-2	PRKCB	S407	P402L	402	Missense	distal	-5	no	1.602	1.621	EPSD	TCGA;ICGC;COSMIC	0.942	Up-regulation
AGC_PKC_PKCa_PRKCB_ST	P98082	DAB2	P05771-2	PRKCB	S407	P402S	402	Missense	distal	-5	no	1.602	1.627	EPSD	TCGA;ICGC;COSMIC	0.942	Up-regulation
AGC_PKC_PKCa_PRKCB_ST	P98082	DAB2	P05771-2	PRKCB	S423	H425R	425	Missense	proximal	2	no	-0.632	5.730	EPSD	TCGA;COSMIC	0.942	Gain
AGC_PKC_PKCa_PRKCB_ST	P98082	DAB2	P05771-2	PRKCB	S436	R441T	441	Missense	distal	5	no	1.854	1.514	EPSD	TCGA;ICGC;COSMIC	0.942	Down-regulation
AGC_PKC_PKCa_PRKCB_ST	P98082	DAB2	P05771-2	PRKCB	S436	Q435E	435	Missense	proximal	-1	no	1.854	1.719	EPSD	TCGA;COSMIC	0.942	Down-regulation
AGC_PKC_PKCa_PRKCB_ST	P98082	DAB2	P05771-2	PRKCB	S723	P725R	725	Missense	proximal	2	no	1.537	7.369	EPSD	TCGA;COSMIC	0.942	Up-regulation
AGC_PKC_PKCa_PRKCB_ST	P98082	DAB2	P05771-2	PRKCB	S723	S723F	723	Missense	central	0	yes	1.537	0.000	EPSD	TCGA;COSMIC;CCLE	0.942	Loss
AGC_PKC_PKCa_PRKCB_ST	P98082	DAB2	P05771-2	PRKCB	S723	S723P	723	Missense	central	0	yes	1.537	0.000	EPSD	TCGA;COSMIC	0.942	Loss
AGC_PKC_PKCa_PRKCB_ST	P05771	PRKCB	P05771-2	PRKCB	S16	A21S	21	Missense	distal	5	no	2.322	2.193	EPSD	TCGA;ICGC	0.942	Down-regulation
AGC_PKC_PKCa_PRKCB_ST	P05771	PRKCB	P05771-2	PRKCB	S16	E14K	14	Missense	proximal	-2	no	2.322	3.766	EPSD	TCGA	0.942	Up-regulation
AGC_PKC_PKCa_PRKCB_ST	P05771	PRKCB	P05771-2	PRKCB	S16	F20S	20	Missense	distal	4	no	2.322	2.471	EPSD	TCGA;ICGC;COSMIC	0.942	Up-regulation
AGC_PKC_PKCa_PRKCB_ST	P05771	PRKCB	P05771-2	PRKCB	S16	R19L	19	Missense	distal	3	no	2.322	1.236	EPSD	TCGA;ICGC;COSMIC	0.942	Down-regulation
AGC_PKC_PKCa_PRKCB_ST	P05771	PRKCB	P05771-2	PRKCB	S16	R19C	19	Missense	distal	3	no	2.322	1.469	EPSD	TCGA;ICGC;COSMIC	0.942	Down-regulation
AGC_PKC_PKCa_PRKCB_ST	P05771	PRKCB	P05771-2	PRKCB	S16	V18M	18	Missense	proximal	2	no	2.322	0.863	EPSD	TCGA;ICGC;COSMIC	0.942	Loss
AGC_PKC_PKCa_PRKCB_ST	P05771	PRKCB	P05771-2	PRKCB	S16	A21T	21	Missense	distal	5	no	2.322	2.260	EPSD	TCGA;ICGC;COSMIC	0.942	Down-regulation
AGC_PKC_PKCa_PRKCB_ST	P05771	PRKCB	P05771-2	PRKCB	T17	A21S	21	Missense	distal	4	no	3.564	4.034	EPSD	TCGA;ICGC	0.942	Up-regulation
AGC_PKC_PKCa_PRKCB_ST	P05771	PRKCB	P05771-2	PRKCB	T17	E14K	14	Missense	distal	-3	no	3.564	6.899	EPSD	TCGA	0.942	Up-regulation
AGC_PKC_PKCa_PRKCB_ST	P05771	PRKCB	P05771-2	PRKCB	T17	F20S	20	Missense	distal	3	no	3.564	3.826	EPSD	TCGA;ICGC;COSMIC	0.942	Up-regulation
AGC_PKC_PKCa_PRKCB_ST	P05771	PRKCB	P05771-2	PRKCB	T17	R19L	19	Missense	proximal	2	no	3.564	-3.068	EPSD	TCGA;ICGC;COSMIC	0.942	Loss
AGC_PKC_PKCa_PRKCB_ST	P05771	PRKCB	P05771-2	PRKCB	T17	R19C	19	Missense	proximal	2	no	3.564	-0.929	EPSD	TCGA;ICGC;COSMIC	0.942	Loss
AGC_PKC_PKCa_PRKCB_ST	P05771	PRKCB	P05771-2	PRKCB	T17	V18M	18	Missense	proximal	1	no	3.564	2.841	EPSD	TCGA;ICGC;COSMIC	0.942	Down-regulation
AGC_PKC_PKCa_PRKCB_ST	P05771	PRKCB	P05771-2	PRKCB	T17	A21T	21	Missense	distal	4	no	3.564	4.006	EPSD	TCGA;ICGC;COSMIC	0.942	Up-regulation
AGC_PKC_PKCa_PRKCB_ST	P05771	PRKCB	P05771-2	PRKCB	T40	A41T	41	Missense	proximal	1	no	3.397	2.951	EPSD	TCGA;ICGC;COSMIC	0.942	Down-regulation
AGC_PKC_PKCa_PRKCB_ST	P05771	PRKCB	P05771-2	PRKCB	T40	R42H	42	Missense	proximal	2	no	3.397	-2.965	EPSD	TCGA;ICGC;COSMIC	0.942	Loss
AGC_PKC_PKCa_PRKCB_ST	P05771	PRKCB	P05771-2	PRKCB	T48	A41T	41	Missense	distal	-7	no	2.065	2.036	EPSD	TCGA;ICGC;COSMIC	0.942	Down-regulation
AGC_PKC_PKCa_PRKCB_ST	P05771	PRKCB	P05771-2	PRKCB	T48	S51R	51	Missense	distal	3	no	2.065	2.830	EPSD	TCGA;ICGC;COSMIC	0.942	Up-regulation
AGC_PKC_PKCa_PRKCB_ST	P05771	PRKCB	P05771-2	PRKCB	T48	D55N	55	Missense	distal	7	no	2.065	2.144	EPSD	TCGA;ICGC;COSMIC	0.942	Up-regulation
AGC_PKC_PKCa_PRKCB_ST	P05771	PRKCB	P05771-2	PRKCB	T48	C53G	53	Missense	distal	5	no	2.065	2.078	EPSD	TCGA;ICGC;COSMIC	0.942	Up-regulation
AGC_PKC_PKCa_PRKCB_ST	P05771	PRKCB	P05771-2	PRKCB	T48	R42H	42	Missense	distal	-6	no	2.065	1.819	EPSD	TCGA;ICGC;COSMIC	0.942	Down-regulation
AGC_PKC_PKCa_PRKCB_ST	P05771	PRKCB	P05771-2	PRKCB	S110	H107R	107	Missense	distal	-3	no	-1.227	1.760	EPSD	TCGA;ICGC;COSMIC	0.942	Gain
AGC_PKC_PKCa_PRKCB_ST	P05771	PRKCB	P05771-2	PRKCB	S111	H107R	107	Missense	distal	-4	no	2.681	2.375	EPSD	TCGA;ICGC;COSMIC	0.942	Down-regulation
AGC_PKC_PKCa_PRKCB_ST	P05771	PRKCB	P05771-2	PRKCB	S111	C115F	115	Missense	distal	4	no	2.681	2.652	EPSD	TCGA;ICGC;COSMIC;GDSC;CCLE	0.942	Down-regulation
AGC_PKC_PKCa_PRKCB_ST	P05771	PRKCB	P05771-2	PRKCB	S111	P112L	112	Missense	proximal	1	no	2.681	3.817	EPSD	TCGA;ICGC;COSMIC	0.942	Up-regulation
AGC_PKC_PKCa_PRKCB_ST	P05771	PRKCB	P05771-2	PRKCB	T314	K309N	309	Missense	distal	-5	no	1.587	1.420	EPSD	TCGA;ICGC;COSMIC	0.942	Down-regulation
AGC_PKC_PKCa_PRKCB_ST	P05771	PRKCB	P05771-2	PRKCB	T314	T314A	314	Missense	central	0	yes	1.587	0.000	EPSD	TCGA;ICGC;COSMIC	0.942	Loss
AGC_PKC_PKCa_PRKCB_ST	P05771	PRKCB	P05771-2	PRKCB	T314	K315N	315	Missense	proximal	1	no	1.587	-1.232	EPSD	TCGA;ICGC;COSMIC	0.942	Loss
AGC_PKC_PKCa_PRKCB_ST	P05771	PRKCB	P05771-2	PRKCB	T314	T321M	321	Missense	distal	7	no	1.587	1.619	EPSD	TCGA;ICGC;COSMIC	0.942	Up-regulation
AGC_PKC_PKCa_PRKCB_ST	P05771	PRKCB	P05771-2	PRKCB	T500	D494N	494	Missense	distal	-6	no	2.613	2.679	EPSD	TCGA;ICGC;COSMIC	0.942	Up-regulation
AGC_PKC_PKCa_PRKCB_ST	P05771	PRKCB	P05771-2	PRKCB	T500	T498I	498	Missense	proximal	-2	no	2.613	2.450	EPSD	TCGA;ICGC;COSMIC	0.942	Down-regulation
AGC_PKC_PKCa_PRKCB_ST	P05771	PRKCB	P05771-2	PRKCB	T500	T498A	498	Missense	proximal	-2	no	2.613	2.208	EPSD	TCGA;ICGC;COSMIC	0.942	Down-regulation
AGC_PKC_PKCa_PRKCB_ST	P05771	PRKCB	P05771-2	PRKCB	T500	F501L	501	Missense	proximal	1	no	2.613	2.113	EPSD	TCGA;ICGC;COSMIC	0.942	Down-regulation
AGC_PKC_PKCa_PRKCB_ST	P05771	PRKCB	P05771-2	PRKCB	S565	A568D	568	Missense	distal	3	no	0.626	0.946	EPSD	TCGA;ICGC;COSMIC	0.942	Gain
AGC_PKC_PKCa_PRKCB_ST	P05771	PRKCB	P05771-2	PRKCB	S565	E567K	567	Missense	proximal	2	no	0.626	6.039	EPSD	TCGA;ICGC;COSMIC;CCLE	0.942	Gain
AGC_PKC_PKCa_PRKCB_ST	P53004	BLVRA	P05771-2	PRKCB	S21	G20S	20	Missense	proximal	-1	no	6.698	6.627	EPSD	TCGA	0.942	Down-regulation
AGC_PKC_PKCa_PRKCB_ST	P53004	BLVRA	P05771-2	PRKCB	S21	R23W	23	Missense	proximal	2	no	6.698	-2.815	EPSD	TCGA;ICGC;COSMIC	0.942	Loss
AGC_PKC_PKCa_PRKCB_ST	P53004	BLVRA	P05771-2	PRKCB	S230	S235C	235	Missense	distal	5	no	1.308	1.271	PhosphoSitePlus;EPSD	TCGA;ICGC;COSMIC	0.942	Down-regulation
AGC_PKC_PKCa_PRKCB_ST	P53004	BLVRA	P05771-2	PRKCB	S230	K234N	234	Missense	distal	4	no	1.308	0.732	PhosphoSitePlus;EPSD	TCGA	0.942	Loss
AGC_PKC_PKCa_PRKCB_ST	P53004	BLVRA	P05771-2	PRKCB	S230	S237C	237	Missense	distal	7	no	1.308	1.335	PhosphoSitePlus;EPSD	TCGA;ICGC;COSMIC	0.942	Up-regulation
AGC_PKC_PKCa_PRKCB_ST	P53004	BLVRA	P05771-2	PRKCB	S230	G236W	236	Missense	distal	6	no	1.308	1.080	PhosphoSitePlus;EPSD	TCGA;ICGC;COSMIC	0.942	Down-regulation
AGC_PKC_PKCa_PRKCB_ST	P53004	BLVRA	P05771-2	PRKCB	S230	N226H	226	Missense	distal	-4	no	1.308	1.307	PhosphoSitePlus;EPSD	TCGA;ICGC;COSMIC	0.942	Down-regulation
AGC_PKC_PKCa_PRKCB_ST	P53004	BLVRA	P05771-2	PRKCB	S230	H232N	232	Missense	proximal	2	no	1.308	2.392	PhosphoSitePlus;EPSD	TCGA;ICGC;COSMIC	0.942	Up-regulation
AGC_PKC_PKCa_PRKCB_ST	Q07869	PPARA	P05771-2	PRKCB	S163	G165R	165	Missense	proximal	2	no	-2.930	5.804	EPSD	TCGA;ICGC;COSMIC	0.942	Gain
AGC_PKC_PKCa_PRKCB_ST	Q07869	PPARA	P05771-2	PRKCB	S179	R172C	172	Missense	distal	-7	no	2.928	3.144	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	0.942	Up-regulation
AGC_PKC_PKCa_PRKCB_ST	Q07869	PPARA	P05771-2	PRKCB	S179	R178I	178	Missense	proximal	-1	no	2.928	2.348	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	0.942	Down-regulation
AGC_PKC_PKCa_PRKCB_ST	P15336	ATF2	P05771-2	PRKCB	S100	E93Q	93	Missense	distal	-7	no	5.803	5.668	EPSD	TCGA;COSMIC	0.942	Down-regulation
AGC_PKC_PKCa_PRKCB_ST	P15336	ATF2	P05771-2	PRKCB	S146	E148K	148	Missense	proximal	2	no	-3.872	1.542	EPSD	TCGA;COSMIC	0.942	Gain
AGC_PKC_PKCa_PRKCB_ST	P15336	ATF2	P05771-2	PRKCB	S314	P312L	312	Missense	proximal	-2	no	1.491	0.804	EPSD	TCGA;COSMIC	0.942	Loss
AGC_PKC_PKCa_PRKCB_ST	P15336	ATF2	P05771-2	PRKCB	S314	S321F	321	Missense	distal	7	no	1.491	1.549	EPSD	TCGA;COSMIC	0.942	Up-regulation
AGC_PKC_PKCa_PRKCB_ST	P15336	ATF2	P05771-2	PRKCB	S314	E308Q	308	Missense	distal	-6	no	1.491	1.473	EPSD	TCGA;COSMIC	0.942	Down-regulation
AGC_PKC_PKCa_PRKCB_ST	P15336	ATF2	P05771-2	PRKCB	S314	S310F	310	Missense	distal	-4	no	1.491	1.470	EPSD	TCGA;COSMIC	0.942	Down-regulation
AGC_PKC_PKCa_PRKCB_ST	P15336	ATF2	P05771-2	PRKCB	S340	P334A	334	Missense	distal	-6	no	2.871	2.908	EPSD	TCGA;COSMIC	0.942	Up-regulation
AGC_PKC_PKCa_PRKCB_ST	P15336	ATF2	P05771-2	PRKCB	S340	T339A	339	Missense	proximal	-1	no	2.871	2.717	EPSD	TCGA;COSMIC	0.942	Down-regulation
AGC_PKC_PKCa_PRKCB_ST	P15336	ATF2	P05771-2	PRKCB	S455	S456L	456	Missense	proximal	1	no	-0.054	1.286	EPSD	TCGA;COSMIC	0.942	Gain
AGC_PKC_PKCa_PRKCB_ST	P43629	KIR3DL1	P05771-2	PRKCB	S245	S239N	239	Missense	distal	-6	no	3.334	3.431	EPSD	TCGA;ICGC;COSMIC	0.942	Up-regulation
AGC_PKC_PKCa_PRKCB_ST	P43629	KIR3DL1	P05771-2	PRKCB	S245	S249C	249	Missense	distal	4	no	3.334	3.213	EPSD	TCGA;ICGC;COSMIC	0.942	Down-regulation
AGC_PKC_PKCa_PRKCB_ST	P43629	KIR3DL1	P05771-2	PRKCB	S245	M252I	252	Missense	distal	7	no	3.334	3.275	EPSD	TCGA;ICGC;COSMIC;GDSC;CCLE	0.942	Down-regulation
AGC_PKC_PKCa_PRKCB_ST	P43629	KIR3DL1	P05771-2	PRKCB	S245	S246F	246	Missense	proximal	1	no	3.334	5.174	EPSD	TCGA;ICGC;COSMIC	0.942	Up-regulation
AGC_PKC_PKCa_PRKCB_ST	P43629	KIR3DL1	P05771-2	PRKCB	S296	F294S	294	Missense	proximal	-2	no	2.010	2.746	EPSD	TCGA;ICGC	0.942	Up-regulation
AGC_PKC_PKCa_PRKCB_ST	P43629	KIR3DL1	P05771-2	PRKCB	S388	E390K	390	Missense	proximal	2	no	-2.942	2.472	EPSD	TCGA;COSMIC	0.942	Gain
AGC_PKC_PKCa_PRKCB_ST	P43629	KIR3DL1	P05771-2	PRKCB	S415	R413C	413	Missense	proximal	-2	no	7.824	6.358	PhosphoSitePlus	TCGA;ICGC;COSMIC	0.942	Down-regulation
AGC_PKC_PKCa_PRKCB_ST	P43629	KIR3DL1	P05771-2	PRKCB	S415	P421H	421	Missense	distal	6	no	7.824	7.621	PhosphoSitePlus	TCGA;COSMIC	0.942	Down-regulation
AGC_PKC_PKCa_PRKCB_ST	P43629	KIR3DL1	P05771-2	PRKCB	S415	Q408K	408	Missense	distal	-7	no	7.824	7.754	PhosphoSitePlus	TCGA;COSMIC	0.942	Down-regulation
AGC_PKC_PKCa_PRKCB_ST	P43629	KIR3DL1	P05771-2	PRKCB	S415	R413H	413	Missense	proximal	-2	no	7.824	5.809	PhosphoSitePlus	TCGA;COSMIC	0.942	Down-regulation
AGC_PKC_PKCa_PRKCB_ST	P43629	KIR3DL1	P05771-2	PRKCB	S415	T412S	412	Missense	distal	-3	no	7.824	6.909	PhosphoSitePlus	TCGA;COSMIC	0.942	Down-regulation
AGC_PKC_PKCa_PRKCB_ST	P43629	KIR3DL1	P05771-2	PRKCB	S415	P418H	418	Missense	distal	3	no	7.824	7.717	PhosphoSitePlus	TCGA;COSMIC	0.942	Down-regulation
AGC_PKC_PKCa_PRKCB_ST	P56537	EIF6	P05771-2	PRKCB	S6	R4P	4	Missense	proximal	-2	no	1.585	-0.247	EPSD	TCGA;ICGC;COSMIC	0.942	Loss
AGC_PKC_PKCa_PRKCB_ST	P56537	EIF6	P05771-2	PRKCB	S235	R237W	237	Missense	proximal	2	no	2.749	-6.764	PhosphoSitePlus	TCGA;ICGC;COSMIC	0.942	Loss
AGC_PKC_PKCa_PRKCB_ST	P56537	EIF6	P05771-2	PRKCB	S239	R237W	237	Missense	proximal	-2	no	1.491	-1.786	EPSD	TCGA;ICGC;COSMIC	0.942	Loss
AGC_PKC_PKCa_PRKCB_ST	Q06124	PTPN11	P05771-2	PRKCB	S140	L136H	136	Missense	distal	-4	no	1.121	1.044	EPSD	TCGA;ICGC;COSMIC	0.942	Down-regulation
AGC_PKC_PKCa_PRKCB_ST	Q06124	PTPN11	P05771-2	PRKCB	S140	S142N	142	Missense	proximal	2	no	1.121	1.840	EPSD	TCGA;ICGC;COSMIC;GDSC;CCLE	0.942	Up-regulation
AGC_PKC_PKCa_PRKCB_ST	Q06124	PTPN11	P05771-2	PRKCB	S140	D146Y	146	Missense	distal	6	no	1.121	0.792	EPSD	TCGA;ICGC;COSMIC	0.942	Loss
AGC_PKC_PKCa_PRKCB_ST	Q06124	PTPN11	P05771-2	PRKCB	S160	D155N	155	Missense	distal	-5	no	0.985	0.919	EPSD	TCGA;ICGC;COSMIC	0.942	Loss
AGC_PKC_PKCa_PRKCB_ST	Q06124	PTPN11	P05771-2	PRKCB	S160	D156N	156	Missense	distal	-4	no	0.985	0.977	EPSD	TCGA;ICGC;COSMIC	0.942	Down-regulation
AGC_PKC_PKCa_PRKCB_ST	Q06124	PTPN11	P05771-2	PRKCB	S160	G163D	163	Missense	distal	3	no	0.985	1.355	EPSD	TCGA;ICGC;COSMIC	0.942	Up-regulation
AGC_PKC_PKCa_PRKCB_ST	Q06124	PTPN11	P05771-2	PRKCB	T397	E400K	400	Missense	distal	3	no	1.295	1.243	EPSD	TCGA;ICGC	0.942	Down-regulation
AGC_PKC_PKCa_PRKCB_ST	Q06124	PTPN11	P05771-2	PRKCB	S503	Q510L	510	Missense	distal	7	no	3.497	3.651	EPSD	TCGA;ICGC;COSMIC	0.942	Up-regulation
AGC_PKC_PKCa_PRKCB_ST	Q06124	PTPN11	P05771-2	PRKCB	S503	Q510H	510	Missense	distal	7	no	3.497	3.647	EPSD	TCGA;ICGC;COSMIC;GDSC;CCLE	0.942	Up-regulation
AGC_PKC_PKCa_PRKCB_ST	P49841	GSK3B	P05771-2	PRKCB	S13	Q19R	19	Missense	distal	6	no	1.665	2.470	EPSD	TCGA	0.942	Up-regulation
AGC_PKC_PKCa_PRKCB_ST	P49841	GSK3B	P05771-2	PRKCB	S25	A22S	22	Missense	distal	-3	no	0.733	1.264	EPSD	TCGA;ICGC	0.942	Gain
AGC_PKC_PKCa_PRKCB_ST	P49841	GSK3B	P05771-2	PRKCB	S35	G34S	34	Missense	proximal	-1	no	2.853	2.782	EPSD	TCGA;COSMIC	0.942	Down-regulation
AGC_PKC_PKCa_PRKCB_ST	P35579	MYH9	P05771-2	PRKCB	S197	A195V	195	Missense	proximal	-2	no	3.845	4.056	EPSD	TCGA;ICGC;COSMIC	0.942	Up-regulation
AGC_PKC_PKCa_PRKCB_ST	P35579	MYH9	P05771-2	PRKCB	S197	A192V	192	Missense	distal	-5	no	3.845	3.815	EPSD	TCGA;ICGC;COSMIC	0.942	Down-regulation
AGC_PKC_PKCa_PRKCB_ST	P35579	MYH9	P05771-2	PRKCB	T226	K228R	228	Missense	proximal	2	no	0.035	1.658	EPSD	TCGA	0.942	Gain
AGC_PKC_PKCa_PRKCB_ST	P35579	MYH9	P05771-2	PRKCB	S232	S233F	233	Missense	proximal	1	no	-0.459	1.380	EPSD	TCGA;ICGC;COSMIC	0.942	Gain
AGC_PKC_PKCa_PRKCB_ST	P35579	MYH9	P05771-2	PRKCB	S344	M337I	337	Missense	distal	-7	no	3.033	2.763	EPSD	TCGA;ICGC;COSMIC	0.942	Down-regulation
AGC_PKC_PKCa_PRKCB_ST	P35579	MYH9	P05771-2	PRKCB	S344	L347F	347	Missense	distal	3	no	3.033	3.091	EPSD	TCGA;ICGC;COSMIC	0.942	Up-regulation
AGC_PKC_PKCa_PRKCB_ST	P35579	MYH9	P05771-2	PRKCB	S541	Q548L	548	Missense	distal	7	no	1.313	1.467	EPSD	TCGA;ICGC;COSMIC	0.942	Up-regulation
AGC_PKC_PKCa_PRKCB_ST	P35579	MYH9	P05771-2	PRKCB	S541	E544D	544	Missense	distal	3	no	1.313	1.058	EPSD	TCGA;ICGC	0.942	Down-regulation
AGC_PKC_PKCa_PRKCB_ST	P35579	MYH9	P05771-2	PRKCB	S541	K536N	536	Missense	distal	-5	no	1.313	1.146	EPSD	TCGA;ICGC;COSMIC	0.942	Down-regulation
AGC_PKC_PKCa_PRKCB_ST	P35579	MYH9	P05771-2	PRKCB	T725	P726S	726	Missense	proximal	1	no	1.022	0.818	EPSD	TCGA;ICGC;COSMIC	0.942	Loss
AGC_PKC_PKCa_PRKCB_ST	P35579	MYH9	P05771-2	PRKCB	S1017	A1019T	1019	Missense	proximal	2	no	-0.586	2.770	EPSD	TCGA;ICGC;COSMIC	0.942	Gain
AGC_PKC_PKCa_PRKCB_ST	P35579	MYH9	P05771-2	PRKCB	S1122	E1115K	1115	Missense	distal	-7	no	1.709	1.505	EPSD	TCGA;ICGC;COSMIC	0.942	Down-regulation
AGC_PKC_PKCa_PRKCB_ST	P35579	MYH9	P05771-2	PRKCB	T1208	K1209E	1209	Missense	proximal	1	no	2.263	0.271	EPSD	TCGA;ICGC;COSMIC	0.942	Loss
AGC_PKC_PKCa_PRKCB_ST	P35579	MYH9	P05771-2	PRKCB	S1243	R1247P	1247	Missense	distal	4	no	2.520	1.637	EPSD	TCGA;ICGC;COSMIC	0.942	Down-regulation
AGC_PKC_PKCa_PRKCB_ST	P35579	MYH9	P05771-2	PRKCB	S1340	E1347K	1347	Missense	distal	7	no	6.141	6.120	EPSD	TCGA;ICGC;COSMIC	0.942	Down-regulation
AGC_PKC_PKCa_PRKCB_ST	P35579	MYH9	P05771-2	PRKCB	S1340	E1337K	1337	Missense	distal	-3	no	6.141	9.476	EPSD	TCGA;ICGC;COSMIC	0.942	Up-regulation
AGC_PKC_PKCa_PRKCB_ST	P35579	MYH9	P05771-2	PRKCB	S1340	R1342W	1342	Missense	proximal	2	no	6.141	-3.372	EPSD	TCGA;ICGC;COSMIC	0.942	Loss
AGC_PKC_PKCa_PRKCB_ST	P35579	MYH9	P05771-2	PRKCB	S1340	S1340P	1340	Missense	central	0	yes	6.141	0.000	EPSD	TCGA;ICGC	0.942	Loss
AGC_PKC_PKCa_PRKCB_ST	P35579	MYH9	P05771-2	PRKCB	S1398	E1402K	1402	Missense	distal	4	no	4.442	5.033	EPSD	TCGA;ICGC;COSMIC	0.942	Up-regulation
AGC_PKC_PKCa_PRKCB_ST	P35579	MYH9	P05771-2	PRKCB	S1511	S1512F	1512	Missense	proximal	1	no	0.299	2.138	EPSD	TCGA;ICGC;COSMIC	0.942	Gain
AGC_PKC_PKCa_PRKCB_ST	P35579	MYH9	P05771-2	PRKCB	S1526	E1531V	1531	Missense	distal	5	no	1.959	1.655	EPSD	TCGA;ICGC;COSMIC	0.942	Down-regulation
AGC_PKC_PKCa_PRKCB_ST	P35579	MYH9	P05771-2	PRKCB	S1526	Q1532R	1532	Missense	distal	6	no	1.959	2.765	EPSD	TCGA;ICGC	0.942	Up-regulation
AGC_PKC_PKCa_PRKCB_ST	P35579	MYH9	P05771-2	PRKCB	S1526	E1522K	1522	Missense	distal	-4	no	1.959	1.696	EPSD	TCGA;ICGC;COSMIC	0.942	Down-regulation
AGC_PKC_PKCa_PRKCB_ST	P35579	MYH9	P05771-2	PRKCB	S1892	R1898C	1898	Missense	distal	6	no	3.035	1.840	EPSD	TCGA;ICGC;COSMIC	0.942	Down-regulation
AGC_PKC_PKCa_PRKCB_ST	P35579	MYH9	P05771-2	PRKCB	S1892	A1891T	1891	Missense	proximal	-1	no	3.035	3.190	EPSD	TCGA;ICGC;COSMIC;GDSC;CCLE	0.942	Up-regulation
AGC_PKC_PKCa_PRKCB_ST	P35579	MYH9	P05771-2	PRKCB	S1915	S1916F	1916	Missense	proximal	1	no	0.074	1.914	EPSD	TCGA;ICGC;COSMIC	0.942	Gain
AGC_PKC_PKCa_PRKCB_ST	P35579	MYH9	P05771-2	PRKCB	S1916	R1912H	1912	Missense	distal	-4	no	4.740	5.046	PhosphoSitePlus	TCGA;ICGC;COSMIC	0.942	Up-regulation
AGC_PKC_PKCa_PRKCB_ST	P35579	MYH9	P05771-2	PRKCB	S1916	S1916F	1916	Missense	central	0	yes	4.740	0.000	PhosphoSitePlus	TCGA;ICGC;COSMIC	0.942	Loss
AGC_PKC_PKCa_PRKCB_ST	P35579	MYH9	P05771-2	PRKCB	S1916	M1910I	1910	Missense	distal	-6	no	4.740	4.734	PhosphoSitePlus	TCGA;ICGC;COSMIC	0.942	Down-regulation
AGC_PKC_PKCa_PRKCB_ST	P35579	MYH9	P05771-2	PRKCB	S1916	A1909V	1909	Missense	distal	-7	no	4.740	4.776	PhosphoSitePlus	TCGA;ICGC;COSMIC	0.942	Up-regulation
AGC_PKC_PKCa_PRKCB_ST	Q9UBS0	RPS6KB2	P05771-2	PRKCB	S254	G256R	256	Missense	proximal	2	no	-5.375	3.359	EPSD	TCGA;ICGC;COSMIC	0.942	Gain
AGC_PKC_PKCa_PRKCB_ST	Q9UBS0	RPS6KB2	P05771-2	PRKCB	S410	S410L	410	Missense	central	0	yes	7.610	0.000	EPSD	TCGA;ICGC;COSMIC	0.942	Loss
AGC_PKC_PKCa_PRKCB_ST	Q9UBS0	RPS6KB2	P05771-2	PRKCB	S417	R419W	419	Missense	proximal	2	no	1.767	-7.746	EPSD	TCGA;ICGC;COSMIC	0.942	Loss
AGC_PKC_PKCa_PRKCB_ST	Q9UBS0	RPS6KB2	P05771-2	PRKCB	S417	S410L	410	Missense	distal	-7	no	1.767	1.761	EPSD	TCGA;ICGC;COSMIC	0.942	Down-regulation
AGC_PKC_PKCa_PRKCB_ST	Q9H1D0	TRPV6	P05771-2	PRKCB	S184	A191T	191	Missense	distal	7	no	3.920	3.829	PhosphoSitePlus;EPSD	TCGA;ICGC	0.942	Down-regulation
AGC_PKC_PKCa_PRKCB_ST	P21730	C5AR1	P05771-2	PRKCB	S327	R320Q	320	Missense	distal	-7	no	1.648	1.673	EPSD	TCGA;ICGC;COSMIC	0.942	Up-regulation
AGC_PKC_PKCa_PRKCB_ST	P21730	C5AR1	P05771-2	PRKCB	S332	S338Y	338	Missense	distal	6	no	1.111	1.006	EPSD	TCGA;ICGC;COSMIC	0.942	Down-regulation
AGC_PKC_PKCa_PRKCB_ST	P21730	C5AR1	P05771-2	PRKCB	S334	S338Y	338	Missense	distal	4	no	0.990	1.405	PhosphoSitePlus	TCGA;ICGC;COSMIC	0.942	Up-regulation
AGC_PKC_PKCa_PRKCB_ST	P14598	NCF1	P05771-2	PRKCB	S103	R110H	110	Missense	distal	7	no	0.933	1.159	EPSD	TCGA;ICGC	0.942	Gain
AGC_PKC_PKCa_PRKCB_ST	P14598	NCF1	P05771-2	PRKCB	T133	N131K	131	Missense	proximal	-2	no	-0.381	1.450	EPSD	TCGA	0.942	Gain
AGC_PKC_PKCa_PRKCB_ST	P14598	NCF1	P05771-2	PRKCB	S328	F331S	331	Missense	distal	3	no	6.012	6.274	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	0.942	Up-regulation
AGC_PKC_PKCa_PRKCB_ST	Q14152	EIF3A	P05771-2	PRKCB	S108	E102G	102	Missense	distal	-6	no	1.189	0.923	EPSD	TCGA;COSMIC	0.942	Loss
AGC_PKC_PKCa_PRKCB_ST	Q14152	EIF3A	P05771-2	PRKCB	S263	H257D	257	Missense	distal	-6	no	1.904	1.967	EPSD	TCGA;COSMIC	0.942	Up-regulation
AGC_PKC_PKCa_PRKCB_ST	Q14152	EIF3A	P05771-2	PRKCB	S263	P266T	266	Missense	distal	3	no	1.904	2.017	EPSD	TCGA;COSMIC	0.942	Up-regulation
AGC_PKC_PKCa_PRKCB_ST	Q14152	EIF3A	P05771-2	PRKCB	S263	H257Y	257	Missense	distal	-6	no	1.904	1.955	EPSD	TCGA;COSMIC	0.942	Up-regulation
AGC_PKC_PKCa_PRKCB_ST	Q14152	EIF3A	P05771-2	PRKCB	S319	S319P	319	Missense	central	0	yes	3.351	0.000	EPSD	TCGA;COSMIC	0.942	Loss
AGC_PKC_PKCa_PRKCB_ST	Q14152	EIF3A	P05771-2	PRKCB	S584	E583D	583	Missense	proximal	-1	no	1.203	1.116	EPSD	TCGA;COSMIC	0.942	Down-regulation
AGC_PKC_PKCa_PRKCB_ST	Q14152	EIF3A	P05771-2	PRKCB	S584	E580K	580	Missense	distal	-4	no	1.203	0.940	EPSD	TCGA	0.942	Loss
AGC_PKC_PKCa_PRKCB_ST	Q14152	EIF3A	P05771-2	PRKCB	T635	R637Q	637	Missense	proximal	2	no	6.625	0.076	EPSD	TCGA;COSMIC	0.942	Loss
AGC_PKC_PKCa_PRKCB_ST	Q14152	EIF3A	P05771-2	PRKCB	S949	R946T	946	Missense	distal	-3	no	7.541	5.060	EPSD	TCGA;COSMIC	0.942	Down-regulation
AGC_PKC_PKCa_PRKCB_ST	Q14152	EIF3A	P05771-2	PRKCB	S949	R956W	956	Missense	distal	7	no	7.541	7.842	EPSD	TCGA	0.942	Up-regulation
AGC_PKC_PKCa_PRKCB_ST	Q14152	EIF3A	P05771-2	PRKCB	S949	L950F	950	Missense	proximal	1	no	7.541	8.041	EPSD	TCGA;COSMIC	0.942	Up-regulation
AGC_PKC_PKCa_PRKCB_ST	Q14152	EIF3A	P05771-2	PRKCB	S949	R956Q	956	Missense	distal	7	no	7.541	7.617	EPSD	TCGA;COSMIC	0.942	Up-regulation
AGC_PKC_PKCa_PRKCB_ST	Q14152	EIF3A	P05771-2	PRKCB	S978	R976G	976	Missense	proximal	-2	no	3.884	2.017	EPSD	TCGA;COSMIC	0.942	Down-regulation
AGC_PKC_PKCa_PRKCB_ST	Q14152	EIF3A	P05771-2	PRKCB	S978	R979H	979	Missense	proximal	1	no	3.884	2.178	EPSD	TCGA;COSMIC;CCLE	0.942	Down-regulation
AGC_PKC_PKCa_PRKCB_ST	Q14152	EIF3A	P05771-2	PRKCB	S988	W989C	989	Missense	proximal	1	no	3.944	3.981	EPSD	TCGA	0.942	Up-regulation
AGC_PKC_PKCa_PRKCB_ST	Q14152	EIF3A	P05771-2	PRKCB	S1028	G1027E	1027	Missense	proximal	-1	no	3.070	3.282	EPSD	TCGA;COSMIC	0.942	Up-regulation
AGC_PKC_PKCa_PRKCB_ST	Q14152	EIF3A	P05771-2	PRKCB	S1059	R1061C	1061	Missense	proximal	2	no	3.998	-0.495	EPSD	TCGA;COSMIC	0.942	Loss
AGC_PKC_PKCa_PRKCB_ST	Q14152	EIF3A	P05771-2	PRKCB	S1059	R1061H	1061	Missense	proximal	2	no	3.998	-2.364	EPSD	TCGA;COSMIC	0.942	Loss
AGC_PKC_PKCa_PRKCB_ST	Q14152	EIF3A	P05771-2	PRKCB	S1059	R1061L	1061	Missense	proximal	2	no	3.998	-2.634	EPSD	TCGA;COSMIC	0.942	Loss
AGC_PKC_PKCa_PRKCB_ST	Q14152	EIF3A	P05771-2	PRKCB	S1059	A1063V	1063	Missense	distal	4	no	3.998	4.550	EPSD	TCGA	0.942	Up-regulation
AGC_PKC_PKCa_PRKCB_ST	Q14152	EIF3A	P05771-2	PRKCB	S1059	A1053T	1053	Missense	distal	-6	no	3.998	4.138	EPSD	TCGA;COSMIC	0.942	Up-regulation
AGC_PKC_PKCa_PRKCB_ST	Q14152	EIF3A	P05771-2	PRKCB	S1059	W1060C	1060	Missense	proximal	1	no	3.998	4.034	EPSD	TCGA	0.942	Up-regulation
AGC_PKC_PKCa_PRKCB_ST	Q14152	EIF3A	P05771-2	PRKCB	S1149	D1155N	1155	Missense	distal	6	no	5.495	5.762	EPSD	TCGA;COSMIC	0.942	Up-regulation
AGC_PKC_PKCa_PRKCB_ST	Q14152	EIF3A	P05771-2	PRKCB	S1149	R1147H	1147	Missense	proximal	-2	no	5.495	3.480	EPSD	TCGA;COSMIC	0.942	Down-regulation
AGC_PKC_PKCa_PRKCB_ST	Q14152	EIF3A	P05771-2	PRKCB	S1149	R1156W	1156	Missense	distal	7	no	5.495	5.796	EPSD	TCGA;COSMIC	0.942	Up-regulation
AGC_PKC_PKCa_PRKCB_ST	Q14152	EIF3A	P05771-2	PRKCB	S1149	R1151H	1151	Missense	proximal	2	no	5.495	-0.867	EPSD	TCGA;COSMIC	0.942	Loss
AGC_PKC_PKCa_PRKCB_ST	Q14152	EIF3A	P05771-2	PRKCB	S1262	S1256C	1256	Missense	distal	-6	no	2.811	2.670	EPSD	TCGA;COSMIC	0.942	Down-regulation
AGC_PKC_PKCa_PRKCB_ST	Q14152	EIF3A	P05771-2	PRKCB	S1263	S1256C	1256	Missense	distal	-7	no	6.275	6.219	EPSD	TCGA;COSMIC	0.942	Down-regulation
AGC_PKC_PKCa_PRKCB_ST	Q14152	EIF3A	P05771-2	PRKCB	S1302	R1304H	1304	Missense	proximal	2	no	2.157	-4.205	EPSD	TCGA;COSMIC;GDSC	0.942	Loss
AGC_PKC_PKCa_PRKCB_ST	Q14152	EIF3A	P05771-2	PRKCB	S1302	S1309Y	1309	Missense	distal	7	no	2.157	2.101	EPSD	TCGA	0.942	Down-regulation
AGC_PKC_PKCa_PRKCB_ST	Q14152	EIF3A	P05771-2	PRKCB	S1302	G1297E	1297	Missense	distal	-5	no	2.157	2.300	EPSD	TCGA	0.942	Up-regulation
AGC_PKC_PKCa_PRKCB_ST	Q14152	EIF3A	P05771-2	PRKCB	S1309	R1312C	1312	Missense	distal	3	no	1.871	1.019	EPSD	TCGA	0.942	Down-regulation
AGC_PKC_PKCa_PRKCB_ST	Q14152	EIF3A	P05771-2	PRKCB	S1309	R1304H	1304	Missense	distal	-5	no	1.871	1.624	EPSD	TCGA;COSMIC;GDSC	0.942	Down-regulation
AGC_PKC_PKCa_PRKCB_ST	Q14152	EIF3A	P05771-2	PRKCB	S1309	S1309Y	1309	Missense	central	0	yes	1.871	0.000	EPSD	TCGA	0.942	Loss
AGC_PKC_PKCa_PRKCB_ST	Q14152	EIF3A	P05771-2	PRKCB	S1309	R1311T	1311	Missense	proximal	2	no	1.871	-2.771	EPSD	TCGA;COSMIC	0.942	Loss
AGC_PKC_PKCa_PRKCB_ST	Q14152	EIF3A	P05771-2	PRKCB	S1309	R1316K	1316	Missense	distal	7	no	1.871	1.982	EPSD	TCGA	0.942	Up-regulation
AGC_PKC_PKCa_PRKCB_ST	Q14152	EIF3A	P05771-2	PRKCB	S1355	E1350K	1350	Missense	distal	-5	no	2.833	2.907	EPSD	TCGA;COSMIC	0.942	Up-regulation
AGC_PKC_PKCa_PRKCB_ST	Q14152	EIF3A	P05771-2	PRKCB	S1364	R1366H	1366	Missense	proximal	2	no	3.567	-2.795	PhosphoSitePlus	TCGA;COSMIC;GDSC;CCLE	0.942	Loss
AGC_PKC_PKCa_PRKCB_ST	Q14152	EIF3A	P05771-2	PRKCB	S1364	R1367H	1367	Missense	distal	3	no	3.567	2.762	PhosphoSitePlus	TCGA;COSMIC;GDSC	0.942	Down-regulation
AGC_PKC_PKCa_PRKCB_ST	P20700	LMNB1	P05771-2	PRKCB	S52	T55A	55	Missense	distal	3	no	1.197	0.804	EPSD	TCGA;ICGC	0.942	Loss
AGC_PKC_PKCa_PRKCB_ST	P20700	LMNB1	P05771-2	PRKCB	S126	A131T	131	Missense	distal	5	no	2.979	2.917	EPSD	TCGA;ICGC;COSMIC;CCLE	0.942	Down-regulation
AGC_PKC_PKCa_PRKCB_ST	P20700	LMNB1	P05771-2	PRKCB	S200	C198F	198	Missense	proximal	-2	no	2.652	1.429	EPSD	TCGA	0.942	Down-regulation
AGC_PKC_PKCa_PRKCB_ST	P20700	LMNB1	P05771-2	PRKCB	T219	E218K	218	Missense	proximal	-1	no	4.447	4.591	EPSD	TCGA;ICGC;COSMIC	0.942	Up-regulation
AGC_PKC_PKCa_PRKCB_ST	P20700	LMNB1	P05771-2	PRKCB	S232	Y238H	238	Missense	distal	6	no	4.265	4.579	EPSD	TCGA;ICGC;COSMIC	0.942	Up-regulation
AGC_PKC_PKCa_PRKCB_ST	P20700	LMNB1	P05771-2	PRKCB	S232	V230A	230	Missense	proximal	-2	no	4.265	4.053	EPSD	TCGA;ICGC;COSMIC	0.942	Down-regulation
AGC_PKC_PKCa_PRKCB_ST	P20700	LMNB1	P05771-2	PRKCB	S288	V286A	286	Missense	proximal	-2	no	3.903	3.691	EPSD	TCGA;ICGC;COSMIC	0.942	Down-regulation
AGC_PKC_PKCa_PRKCB_ST	P20700	LMNB1	P05771-2	PRKCB	S302	S296N	296	Missense	distal	-6	no	2.387	2.484	EPSD	TCGA;ICGC	0.942	Up-regulation
AGC_PKC_PKCa_PRKCB_ST	P20700	LMNB1	P05771-2	PRKCB	S302	R299I	299	Missense	distal	-3	no	2.387	-0.808	EPSD	TCGA;ICGC;COSMIC	0.942	Loss
AGC_PKC_PKCa_PRKCB_ST	P20700	LMNB1	P05771-2	PRKCB	S302	R297H	297	Missense	distal	-5	no	2.387	2.140	EPSD	TCGA;ICGC;COSMIC	0.942	Down-regulation
AGC_PKC_PKCa_PRKCB_ST	P20700	LMNB1	P05771-2	PRKCB	T340	M346L	346	Missense	distal	6	no	2.010	1.688	EPSD	TCGA;COSMIC	0.942	Down-regulation
AGC_PKC_PKCa_PRKCB_ST	P20700	LMNB1	P05771-2	PRKCB	T340	M338V	338	Missense	proximal	-2	no	2.010	2.468	EPSD	TCGA;ICGC;COSMIC	0.942	Up-regulation
AGC_PKC_PKCa_PRKCB_ST	P20700	LMNB1	P05771-2	PRKCB	T340	R337H	337	Missense	distal	-3	no	2.010	-0.977	EPSD	TCGA;ICGC;COSMIC	0.942	Loss
AGC_PKC_PKCa_PRKCB_ST	P20700	LMNB1	P05771-2	PRKCB	S405	R410C	410	Missense	distal	5	no	7.169	6.726	PhosphoSitePlus;EPSD	TCGA;ICGC;COSMIC	0.942	Down-regulation
AGC_PKC_PKCa_PRKCB_ST	P20700	LMNB1	P05771-2	PRKCB	S408	R410C	410	Missense	proximal	2	no	1.690	-2.803	EPSD	TCGA;ICGC;COSMIC	0.942	Loss
AGC_PKC_PKCa_PRKCB_ST	P20700	LMNB1	P05771-2	PRKCB	T411	R410C	410	Missense	proximal	-1	no	2.783	2.079	EPSD	TCGA;ICGC;COSMIC	0.942	Down-regulation
AGC_PKC_PKCa_PRKCB_ST	P20700	LMNB1	P05771-2	PRKCB	S481	Y482F	482	Missense	proximal	1	no	4.071	4.698	EPSD	TCGA;ICGC;COSMIC	0.942	Up-regulation
AGC_PKC_PKCa_PRKCB_ST	P20700	LMNB1	P05771-2	PRKCB	T575	N580S	580	Missense	distal	5	no	1.841	1.747	EPSD	TCGA;ICGC;COSMIC	0.942	Down-regulation
AGC_PKC_PKCa_PRKCB_ST	P20700	LMNB1	P05771-2	PRKCB	T575	S582R	582	Missense	distal	7	no	1.841	1.671	EPSD	TCGA	0.942	Down-regulation
AGC_PKC_PKCa_PRKCB_ST	P20700	LMNB1	P05771-2	PRKCB	T575	N580T	580	Missense	distal	5	no	1.841	1.813	EPSD	TCGA;ICGC;COSMIC	0.942	Down-regulation
AGC_PKC_PKCa_PRKCB_ST	P20700	LMNB1	P05771-2	PRKCB	T575	R581I	581	Missense	distal	6	no	1.841	0.707	EPSD	TCGA;ICGC	0.942	Loss
AGC_PKC_PKCa_PRKCB_ST	P20700	LMNB1	P05771-2	PRKCB	S579	N580S	580	Missense	proximal	1	no	2.788	3.470	EPSD	TCGA;ICGC;COSMIC	0.942	Up-regulation
AGC_PKC_PKCa_PRKCB_ST	P20700	LMNB1	P05771-2	PRKCB	S579	S582R	582	Missense	distal	3	no	2.788	3.553	EPSD	TCGA	0.942	Up-regulation
AGC_PKC_PKCa_PRKCB_ST	P20700	LMNB1	P05771-2	PRKCB	S579	A584V	584	Missense	distal	5	no	2.788	2.653	EPSD	TCGA;ICGC	0.942	Down-regulation
AGC_PKC_PKCa_PRKCB_ST	P20700	LMNB1	P05771-2	PRKCB	S579	N580T	580	Missense	proximal	1	no	2.788	3.634	EPSD	TCGA;ICGC;COSMIC	0.942	Up-regulation
AGC_PKC_PKCa_PRKCB_ST	P20700	LMNB1	P05771-2	PRKCB	S579	R581I	581	Missense	proximal	2	no	2.788	-2.494	EPSD	TCGA;ICGC	0.942	Loss
AGC_PKC_PKCa_PRKCB_ST	Q04637	EIF4G1	P05771-2	PRKCB	S45	S45Y	45	Missense	central	0	yes	1.205	0.000	EPSD	TCGA;COSMIC	0.942	Loss
AGC_PKC_PKCa_PRKCB_ST	P62491	RAB11A	P05771-2	PRKCB	S177	S177F	177	Missense	central	0	yes	5.356	0.000	PhosphoSitePlus	TCGA;ICGC;COSMIC	0.942	Loss
AGC_PKC_PKCa_PRKCB_ST	P62491	RAB11A	P05771-2	PRKCB	S177	R174H	174	Missense	distal	-3	no	5.356	2.369	PhosphoSitePlus	TCGA;ICGC;COSMIC	0.942	Down-regulation
AGC_PKC_PKCa_PRKCB_ST	P62491	RAB11A	P05771-2	PRKCB	S177	E171D	171	Missense	distal	-6	no	5.356	5.259	PhosphoSitePlus	TCGA;ICGC	0.942	Down-regulation
AGC_PKC_PKCa_PRKCB_ST	O15350	TP73	P05771-2	PRKCB	S235	G232A	232	Missense	distal	-3	no	0.758	1.046	EPSD	TCGA	0.942	Gain
AGC_PKC_PKCa_PRKCB_ST	O15350	TP73	P05771-2	PRKCB	S326	A324V	324	Missense	proximal	-2	no	6.967	7.179	EPSD	TCGA;ICGC;COSMIC	0.942	Up-regulation
AGC_PKC_PKCa_PRKCB_ST	O15350	TP73	P05771-2	PRKCB	S388	P382L	382	Missense	distal	-6	no	2.009	2.025	PhosphoSitePlus	TCGA;ICGC;COSMIC	0.942	Up-regulation
AGC_PKC_PKCa_PRKCB_ST	O15350	TP73	P05771-2	PRKCB	S388	D387Y	387	Missense	proximal	-1	no	2.009	2.054	PhosphoSitePlus	TCGA;ICGC;COSMIC	0.942	Up-regulation
AGC_PKC_PKCa_PRKCB_ST	O15350	TP73	P05771-2	PRKCB	S388	Q391R	391	Missense	distal	3	no	2.009	2.574	PhosphoSitePlus	TCGA;ICGC;COSMIC;CCLE	0.942	Up-regulation
AGC_PKC_PKCa_PRKCB_ST	O15350	TP73	P05771-2	PRKCB	S388	V386G	386	Missense	proximal	-2	no	2.009	1.723	PhosphoSitePlus	TCGA;ICGC	0.942	Down-regulation
AGC_PKC_PKCa_PRKCB_ST	O15350	TP73	P05771-2	PRKCB	S426	G419W	419	Missense	distal	-7	no	3.051	3.121	EPSD	TCGA;COSMIC	0.942	Up-regulation
AGC_PKC_PKCa_PRKCB_ST	P28329	CHAT	P05771-2	PRKCB	T373	D379Y	379	Missense	distal	6	no	4.094	3.766	EPSD	TCGA;COSMIC	0.942	Down-regulation
AGC_PKC_PKCa_PRKCB_ST	P28329	CHAT	P05771-2	PRKCB	T373	S377L	377	Missense	distal	4	no	4.094	3.806	EPSD	TCGA;COSMIC	0.942	Down-regulation
AGC_PKC_PKCa_PRKCB_ST	P28329	CHAT	P05771-2	PRKCB	S377	D379Y	379	Missense	proximal	2	no	1.429	1.612	EPSD	TCGA;COSMIC	0.942	Up-regulation
AGC_PKC_PKCa_PRKCB_ST	P28329	CHAT	P05771-2	PRKCB	S377	S377L	377	Missense	central	0	yes	1.429	0.000	EPSD	TCGA;COSMIC	0.942	Loss
AGC_PKC_PKCa_PRKCB_ST	P28329	CHAT	P05771-2	PRKCB	T462	H460L	460	Missense	proximal	-2	no	1.163	0.658	EPSD	TCGA;COSMIC	0.942	Loss
AGC_PKC_PKCa_PRKCB_ST	P28329	CHAT	P05771-2	PRKCB	T462	L457M	457	Missense	distal	-5	no	1.163	1.171	EPSD	TCGA;COSMIC	0.942	Up-regulation
AGC_PKC_PKCa_PRKCB_ST	P28329	CHAT	P05771-2	PRKCB	T462	R466K	466	Missense	distal	4	no	1.163	1.048	EPSD	TCGA;COSMIC	0.942	Down-regulation
AGC_PKC_PKCa_PRKCB_ST	P28329	CHAT	P05771-2	PRKCB	S464	H460L	460	Missense	distal	-4	no	5.753	5.830	EPSD	TCGA;COSMIC	0.942	Up-regulation
AGC_PKC_PKCa_PRKCB_ST	P28329	CHAT	P05771-2	PRKCB	S464	L457M	457	Missense	distal	-7	no	5.753	5.866	EPSD	TCGA;COSMIC	0.942	Up-regulation
AGC_PKC_PKCa_PRKCB_ST	P28329	CHAT	P05771-2	PRKCB	S464	R470Q	470	Missense	distal	6	no	5.753	4.948	EPSD	TCGA;COSMIC	0.942	Down-regulation
AGC_PKC_PKCa_PRKCB_ST	P28329	CHAT	P05771-2	PRKCB	S464	R466K	466	Missense	proximal	2	no	5.753	4.129	EPSD	TCGA;COSMIC	0.942	Down-regulation
AGC_PKC_PKCa_PRKCB_ST	P28329	CHAT	P05771-2	PRKCB	S465	H460L	460	Missense	distal	-5	no	4.475	4.468	EPSD	TCGA;COSMIC	0.942	Down-regulation
AGC_PKC_PKCa_PRKCB_ST	P28329	CHAT	P05771-2	PRKCB	S465	R470Q	470	Missense	distal	5	no	4.475	4.498	EPSD	TCGA;COSMIC	0.942	Up-regulation
AGC_PKC_PKCa_PRKCB_ST	P28329	CHAT	P05771-2	PRKCB	S465	R466K	466	Missense	proximal	1	no	4.475	4.589	EPSD	TCGA;COSMIC	0.942	Up-regulation
AGC_PKC_PKCa_PRKCB_ST	P28329	CHAT	P05771-2	PRKCB	S558	A557V	557	Missense	proximal	-1	no	6.129	6.233	EPSD	TCGA;COSMIC	0.942	Up-regulation
AGC_PKC_PKCa_PRKCB_ST	P28329	CHAT	P05771-2	PRKCB	S558	P552L	552	Missense	distal	-6	no	6.129	6.144	EPSD	TCGA;COSMIC	0.942	Up-regulation
AGC_PKC_PKCa_PRKCB_ST	P28329	CHAT	P05771-2	PRKCB	S558	S556R	556	Missense	proximal	-2	no	6.129	8.081	EPSD	TCGA;COSMIC	0.942	Up-regulation
AGC_PKC_PKCa_PRKCB_ST	P28329	CHAT	P05771-2	PRKCB	S558	G565E	565	Missense	distal	7	no	6.129	5.960	EPSD	TCGA;COSMIC	0.942	Down-regulation
AGC_PKC_PKCa_PRKCB_ST	P35637	FUS	P05771-2	PRKCB	S257	G256R	256	Missense	proximal	-1	no	4.568	5.101	PhosphoSitePlus	TCGA;ICGC;COSMIC;GDSC	0.942	Up-regulation
AGC_PKC_PKCa_PRKCB_ST	P35637	FUS	P05771-2	PRKCB	S277	E278K	278	Missense	proximal	1	no	1.565	3.557	EPSD	TCGA;ICGC;COSMIC	0.942	Up-regulation
AGC_PKC_PKCa_PRKCB_ST	P35637	FUS	P05771-2	PRKCB	T326	Q319H	319	Missense	distal	-7	no	2.138	2.438	EPSD	TCGA;ICGC;COSMIC	0.942	Up-regulation
AGC_PKC_PKCa_PRKCB_ST	P35637	FUS	P05771-2	PRKCB	S346	I351V	351	Missense	distal	5	no	1.509	1.416	EPSD	TCGA;COSMIC	0.942	Down-regulation
AGC_PKC_PKCa_PRKCB_ST	P35637	FUS	P05771-2	PRKCB	S346	A349G	349	Missense	distal	3	no	1.509	1.460	EPSD	TCGA	0.942	Down-regulation
AGC_PKC_PKCa_PRKCB_ST	P35637	FUS	P05771-2	PRKCB	S346	W353R	353	Missense	distal	7	no	1.509	1.209	EPSD	TCGA;COSMIC	0.942	Down-regulation
AGC_PKC_PKCa_PRKCB_ST	P35637	FUS	P05771-2	PRKCB	S360	F359L	359	Missense	proximal	-1	no	1.325	1.167	EPSD	TCGA	0.942	Down-regulation
AGC_PKC_PKCa_PRKCB_ST	P35637	FUS	P05771-2	PRKCB	S360	W353R	353	Missense	distal	-7	no	1.325	0.904	EPSD	TCGA;COSMIC	0.942	Loss
AGC_PKC_PKCa_PRKCB_ST	P35637	FUS	P05771-2	PRKCB	S439	E443K	443	Missense	distal	4	no	4.862	5.453	EPSD	TCGA;COSMIC	0.942	Up-regulation
AGC_PKC_PKCa_PRKCB_ST	P35637	FUS	P05771-2	PRKCB	S439	N437S	437	Missense	proximal	-2	no	4.862	4.630	EPSD	TCGA;COSMIC	0.942	Down-regulation
AGC_PKC_PKCa_PRKCB_ST	Q9UBU3	GHRL	P05771-2	PRKCB	S41	S41L	41	Missense	central	0	yes	9.523	0.000	PhosphoSitePlus	TCGA;COSMIC	0.942	Loss
AGC_PKC_PKCa_PRKCB_ST	P49840	GSK3A	P05771-2	PRKCB	S266	D263N	263	Missense	distal	-3	no	2.948	3.917	EPSD	TCGA;ICGC	0.942	Up-regulation
AGC_PKC_PKCa_PRKCB_ST	P49840	GSK3A	P05771-2	PRKCB	S266	L270W	270	Missense	distal	4	no	2.948	2.511	EPSD	TCGA;ICGC;COSMIC	0.942	Down-regulation
AGC_PKC_PKCa_PRKCB_ST	P49840	GSK3A	P05771-2	PRKCB	S266	C262R	262	Missense	distal	-4	no	2.948	2.442	EPSD	TCGA;ICGC;COSMIC	0.942	Down-regulation
AGC_PKC_PKCa_PRKCB_ST	P49840	GSK3A	P05771-2	PRKCB	S266	G265D	265	Missense	proximal	-1	no	2.948	3.074	EPSD	TCGA;ICGC	0.942	Up-regulation
AGC_PKC_PKCa_PRKCB_ST	P49840	GSK3A	P05771-2	PRKCB	S266	Q269P	269	Missense	distal	3	no	2.948	2.814	EPSD	TCGA;ICGC	0.942	Down-regulation
TK_Syk_SYK_Y	P02730	SLC4A1	P43405	SYK	Y8	E14D	14	Missense	distal	6	no	18.384	18.167	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	13.041	Down-regulation
TK_Syk_SYK_Y	P02730	SLC4A1	P43405	SYK	Y8	E2K	2	Missense	distal	-6	no	18.384	17.553	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	13.041	Down-regulation
TK_Syk_SYK_Y	P02730	SLC4A1	P43405	SYK	Y8	Q5R	5	Missense	distal	-3	no	18.384	18.449	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	13.041	Up-regulation
TK_Syk_SYK_Y	P02730	SLC4A1	P43405	SYK	Y8	E13D	13	Missense	distal	5	no	18.384	18.496	EPSD;PhosphoSitePlus	TCGA;ICGC	13.041	Up-regulation
TK_Syk_SYK_Y	P02730	SLC4A1	P43405	SYK	Y21	L16M	16	Missense	distal	-5	no	26.467	27.085	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	13.041	Up-regulation
TK_Syk_SYK_Y	P02730	SLC4A1	P43405	SYK	Y21	E14D	14	Missense	distal	-7	no	26.467	26.044	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	13.041	Down-regulation
TK_Syk_SYK_Y	P02730	SLC4A1	P43405	SYK	Y21	E20K	20	Missense	proximal	-1	no	26.467	24.347	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	13.041	Down-regulation
TK_Syk_SYK_Y	P02730	SLC4A1	P43405	SYK	Y21	P24T	24	Missense	distal	3	no	26.467	22.350	EPSD;PhosphoSitePlus	TCGA;ICGC	13.041	Down-regulation
TK_Syk_SYK_Y	P02730	SLC4A1	P43405	SYK	Y21	P24S	24	Missense	distal	3	no	26.467	22.641	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	13.041	Down-regulation
TK_Syk_SYK_Y	P02730	SLC4A1	P43405	SYK	Y359	P354Q	354	Missense	distal	-5	no	17.193	17.001	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	13.041	Down-regulation
TK_Syk_SYK_Y	P02730	SLC4A1	P43405	SYK	Y904	E899D	899	Missense	distal	-5	no	22.145	22.324	PhosphoSitePlus;EPSD	TCGA;ICGC;COSMIC	13.041	Up-regulation
TK_Syk_SYK_Y	P02730	SLC4A1	P43405	SYK	Y904	D905N	905	Missense	proximal	1	no	22.145	20.826	PhosphoSitePlus;EPSD	TCGA;ICGC;COSMIC	13.041	Down-regulation
TK_Syk_SYK_Y	P02730	SLC4A1	P43405	SYK	Y904	A908T	908	Missense	distal	4	no	22.145	22.310	PhosphoSitePlus;EPSD	TCGA;ICGC;COSMIC	13.041	Up-regulation
TK_Syk_SYK_Y	P02730	SLC4A1	P43405	SYK	Y904	E906K	906	Missense	proximal	2	no	22.145	20.087	PhosphoSitePlus;EPSD	TCGA;ICGC;COSMIC;CCLE	13.041	Down-regulation
TK_Syk_SYK_Y	P02730	SLC4A1	P43405	SYK	Y904	P910L	910	Missense	distal	6	no	22.145	21.740	PhosphoSitePlus;EPSD	TCGA;ICGC;COSMIC;CCLE	13.041	Down-regulation
TK_Syk_SYK_Y	P02730	SLC4A1	P43405	SYK	Y904	R901Q	901	Missense	distal	-3	no	22.145	22.079	PhosphoSitePlus;EPSD	TCGA;ICGC;COSMIC	13.041	Down-regulation
TK_Syk_SYK_Y	P29353	SHC1	P43405	SYK	Y349	P354A	354	Missense	distal	5	no	15.004	15.120	EPSD	TCGA;COSMIC	13.041	Up-regulation
TK_Syk_SYK_Y	P29353	SHC1	P43405	SYK	Y349	F353L	353	Missense	distal	4	no	15.004	15.105	EPSD	TCGA;COSMIC	13.041	Up-regulation
TK_Syk_SYK_Y	P29353	SHC1	P43405	SYK	Y349	P344S	344	Missense	distal	-5	no	15.004	15.393	EPSD	TCGA;COSMIC	13.041	Up-regulation
TK_Syk_SYK_Y	P29353	SHC1	P43405	SYK	Y350	P354A	354	Missense	distal	4	no	15.904	15.607	EPSD	TCGA;COSMIC	13.041	Down-regulation
TK_Syk_SYK_Y	P29353	SHC1	P43405	SYK	Y350	E357K	357	Missense	distal	7	no	15.904	15.586	EPSD	TCGA;COSMIC	13.041	Down-regulation
TK_Syk_SYK_Y	P29353	SHC1	P43405	SYK	Y350	F353L	353	Missense	distal	3	no	15.904	19.371	EPSD	TCGA;COSMIC	13.041	Up-regulation
TK_Syk_SYK_Y	P29353	SHC1	P43405	SYK	Y350	P344S	344	Missense	distal	-6	no	15.904	16.371	EPSD	TCGA;COSMIC	13.041	Up-regulation
TK_Syk_SYK_Y	Q8IWV1	LAX1	P43405	SYK	Y193	P197H	197	Missense	distal	4	no	21.486	21.108	EPSD;PhosphoSitePlus	TCGA	13.041	Down-regulation
TK_Syk_SYK_Y	Q8IWV1	LAX1	P43405	SYK	Y193	S187L	187	Missense	distal	-6	no	21.486	20.546	EPSD;PhosphoSitePlus	TCGA;COSMIC	13.041	Down-regulation
TK_Syk_SYK_Y	Q8IWV1	LAX1	P43405	SYK	Y193	S190L	190	Missense	distal	-3	no	21.486	16.367	EPSD;PhosphoSitePlus	TCGA;COSMIC	13.041	Down-regulation
TK_Syk_SYK_Y	Q8IWV1	LAX1	P43405	SYK	Y193	A199S	199	Missense	distal	6	no	21.486	21.817	EPSD;PhosphoSitePlus	TCGA;COSMIC	13.041	Up-regulation
TK_Syk_SYK_Y	Q8IWV1	LAX1	P43405	SYK	Y268	D275Y	275	Missense	distal	7	no	21.314	20.546	PhosphoSitePlus;EPSD	TCGA;COSMIC	13.041	Down-regulation
TK_Syk_SYK_Y	Q8IWV1	LAX1	P43405	SYK	Y268	Q263E	263	Missense	distal	-5	no	21.314	22.200	PhosphoSitePlus;EPSD	TCGA;COSMIC	13.041	Up-regulation
TK_Syk_SYK_Y	Q8IWV1	LAX1	P43405	SYK	Y268	S265P	265	Missense	distal	-3	no	21.314	18.444	PhosphoSitePlus;EPSD	TCGA;COSMIC	13.041	Down-regulation
TK_Syk_SYK_Y	Q8IWV1	LAX1	P43405	SYK	Y268	Q263H	263	Missense	distal	-5	no	21.314	21.431	PhosphoSitePlus;EPSD	TCGA;COSMIC	13.041	Up-regulation
TK_Syk_SYK_Y	P19174	PLCG1	P43405	SYK	Y472	M479I	479	Missense	distal	7	no	16.799	16.684	EPSD	TCGA;ICGC;COSMIC	13.041	Down-regulation
TK_Syk_SYK_Y	P19174	PLCG1	P43405	SYK	Y481	M479I	479	Missense	proximal	-2	no	14.244	14.593	EPSD	TCGA;ICGC;COSMIC	13.041	Up-regulation
TK_Syk_SYK_Y	P19174	PLCG1	P43405	SYK	Y481	I486M	486	Missense	distal	5	no	14.244	14.227	EPSD	TCGA;ICGC;COSMIC	13.041	Down-regulation
TK_Syk_SYK_Y	P19174	PLCG1	P43405	SYK	Y481	N484Y	484	Missense	distal	3	no	14.244	13.225	EPSD	TCGA;ICGC;COSMIC	13.041	Down-regulation
TK_Syk_SYK_Y	P19174	PLCG1	P43405	SYK	Y771	A767P	767	Missense	distal	-4	no	17.856	18.104	PhosphoSitePlus;EPSD	TCGA;ICGC;COSMIC	13.041	Up-regulation
TK_Syk_SYK_Y	P19174	PLCG1	P43405	SYK	Y771	R778C	778	Missense	distal	7	no	17.856	17.597	PhosphoSitePlus;EPSD	TCGA;ICGC;COSMIC;GDSC;CCLE	13.041	Down-regulation
TK_Syk_SYK_Y	P19174	PLCG1	P43405	SYK	Y783	F782L	782	Missense	proximal	-1	no	15.446	13.853	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	13.041	Down-regulation
TK_Syk_SYK_Y	P19174	PLCG1	P43405	SYK	Y783	P788H	788	Missense	distal	5	no	15.446	15.491	EPSD;PhosphoSitePlus	TCGA;ICGC	13.041	Up-regulation
TK_Syk_SYK_Y	P19174	PLCG1	P43405	SYK	Y783	R778C	778	Missense	distal	-5	no	15.446	15.027	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC;GDSC;CCLE	13.041	Down-regulation
TK_Syk_SYK_Y	Q8WV28	BLNK	P43405	SYK	Y72	E77K	77	Missense	distal	5	no	26.174	26.362	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC;CCLE	13.041	Up-regulation
TK_Syk_SYK_Y	Q8WV28	BLNK	P43405	SYK	Y72	S79L	79	Missense	distal	7	no	26.174	25.475	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	13.041	Down-regulation
TK_Syk_SYK_Y	Q8WV28	BLNK	P43405	SYK	Y72	S70N	70	Missense	proximal	-2	no	26.174	26.087	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	13.041	Down-regulation
TK_Syk_SYK_Y	Q8WV28	BLNK	P43405	SYK	Y84	E77K	77	Missense	distal	-7	no	22.896	22.129	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC;CCLE	13.041	Down-regulation
TK_Syk_SYK_Y	Q8WV28	BLNK	P43405	SYK	Y84	V85M	85	Missense	proximal	1	no	22.896	21.078	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC;CCLE	13.041	Down-regulation
TK_Syk_SYK_Y	Q8WV28	BLNK	P43405	SYK	Y84	P87S	87	Missense	distal	3	no	22.896	19.069	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	13.041	Down-regulation
TK_Syk_SYK_Y	Q8WV28	BLNK	P43405	SYK	Y84	S79L	79	Missense	distal	-5	no	22.896	21.743	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	13.041	Down-regulation
TK_Syk_SYK_Y	Q8WV28	BLNK	P43405	SYK	Y84	Y84C	84	Missense	central	0	yes	22.896	0.000	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	13.041	Loss
TK_Syk_SYK_Y	Q8WV28	BLNK	P43405	SYK	Y96	E102K	102	Missense	distal	6	no	27.373	26.949	PhosphoSitePlus;EPSD	TCGA;ICGC;COSMIC	13.041	Down-regulation
TK_Syk_SYK_Y	Q8WV28	BLNK	P43405	SYK	Y178	D184H	184	Missense	distal	6	no	20.252	19.890	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	13.041	Down-regulation
TK_Syk_SYK_Y	Q8WV28	BLNK	P43405	SYK	Y178	E175Q	175	Missense	distal	-3	no	20.252	15.694	EPSD;PhosphoSitePlus	TCGA;ICGC	13.041	Down-regulation
TK_Syk_SYK_Y	Q8WV28	BLNK	P43405	SYK	Y178	P181T	181	Missense	distal	3	no	20.252	16.134	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	13.041	Down-regulation
TK_Syk_SYK_Y	Q8WV28	BLNK	P43405	SYK	Y178	E183K	183	Missense	distal	5	no	20.252	20.439	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	13.041	Up-regulation
TK_Syk_SYK_Y	Q8WV28	BLNK	P43405	SYK	Y178	D174N	174	Missense	distal	-4	no	20.252	19.008	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	13.041	Down-regulation
TK_Syk_SYK_Y	Q8WV28	BLNK	P43405	SYK	Y189	D184H	184	Missense	distal	-5	no	24.592	23.644	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	13.041	Down-regulation
TK_Syk_SYK_Y	Q8WV28	BLNK	P43405	SYK	Y189	E194K	194	Missense	distal	5	no	24.592	24.780	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	13.041	Up-regulation
TK_Syk_SYK_Y	Q8WV28	BLNK	P43405	SYK	Y189	E183K	183	Missense	distal	-6	no	24.592	23.761	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	13.041	Down-regulation
TK_Syk_SYK_Y	Q8WV28	BLNK	P43405	SYK	Y189	E187K	187	Missense	proximal	-2	no	24.592	22.705	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	13.041	Down-regulation
TK_Syk_SYK_Y	P16885	PLCG2	P43405	SYK	Y647	W646G	646	Missense	proximal	-1	no	11.649	14.472	EPSD	TCGA;ICGC;COSMIC	13.041	Gain
TK_Syk_SYK_Y	P16885	PLCG2	P43405	SYK	Y759	D754N	754	Missense	distal	-5	no	16.328	15.798	PhosphoSitePlus	TCGA;ICGC;COSMIC	13.041	Down-regulation
TK_Syk_SYK_Y	P16885	PLCG2	P43405	SYK	Y759	D754A	754	Missense	distal	-5	no	16.328	15.196	PhosphoSitePlus	TCGA;ICGC;COSMIC	13.041	Down-regulation
TK_Syk_SYK_Y	P16885	PLCG2	P43405	SYK	Y759	S763N	763	Missense	distal	4	no	16.328	16.347	PhosphoSitePlus	TCGA;ICGC;COSMIC	13.041	Up-regulation
TK_Syk_SYK_Y	P16885	PLCG2	P43405	SYK	Y759	V755I	755	Missense	distal	-4	no	16.328	16.724	PhosphoSitePlus	TCGA;ICGC;COSMIC	13.041	Up-regulation
TK_Syk_SYK_Y	P16885	PLCG2	P43405	SYK	Y811	G812V	812	Missense	proximal	1	no	13.402	12.933	EPSD	TCGA;ICGC;COSMIC	13.041	Loss
TK_Syk_SYK_Y	P16885	PLCG2	P43405	SYK	Y1048	M1043V	1043	Missense	distal	-5	no	16.841	16.793	EPSD	TCGA;ICGC;COSMIC	13.041	Down-regulation
TK_Syk_SYK_Y	P16885	PLCG2	P43405	SYK	Y1048	E1046D	1046	Missense	proximal	-2	no	16.841	17.647	EPSD	TCGA;ICGC;COSMIC	13.041	Up-regulation
TK_Syk_SYK_Y	P14317	HCLS1	P43405	SYK	Y177	L173V	173	Missense	distal	-4	no	12.126	13.212	EPSD	TCGA;ICGC;COSMIC	13.041	Gain
TK_Syk_SYK_Y	P14317	HCLS1	P43405	SYK	Y177	G179E	179	Missense	proximal	2	no	12.126	13.906	EPSD	TCGA;ICGC;COSMIC	13.041	Gain
TK_Syk_SYK_Y	P14317	HCLS1	P43405	SYK	Y378	E375K	375	Missense	distal	-3	no	30.061	27.181	PhosphoSitePlus;EPSD	TCGA;ICGC;COSMIC	13.041	Down-regulation
TK_Syk_SYK_Y	P14317	HCLS1	P43405	SYK	Y378	E373D	373	Missense	distal	-5	no	30.061	30.240	PhosphoSitePlus;EPSD	TCGA;ICGC;COSMIC	13.041	Up-regulation
TK_Syk_SYK_Y	P14317	HCLS1	P43405	SYK	Y378	D380Y	380	Missense	proximal	2	no	30.061	25.775	PhosphoSitePlus;EPSD	TCGA;ICGC;COSMIC	13.041	Down-regulation
TK_Syk_SYK_Y	P14317	HCLS1	P43405	SYK	Y378	P372L	372	Missense	distal	-6	no	30.061	29.586	PhosphoSitePlus;EPSD	TCGA;ICGC;COSMIC	13.041	Down-regulation
TK_Syk_SYK_Y	P14317	HCLS1	P43405	SYK	Y378	E373K	373	Missense	distal	-5	no	30.061	29.406	PhosphoSitePlus;EPSD	TCGA	13.041	Down-regulation
TK_Syk_SYK_Y	P14317	HCLS1	P43405	SYK	Y397	D391N	391	Missense	distal	-6	no	29.543	29.093	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	13.041	Down-regulation
TK_Syk_SYK_Y	P14317	HCLS1	P43405	SYK	Y397	Y397S	397	Missense	central	0	yes	29.543	0.000	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	13.041	Loss
TK_Syk_SYK_Y	P14317	HCLS1	P43405	SYK	Y397	E398K	398	Missense	proximal	1	no	29.543	26.062	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	13.041	Down-regulation
TK_Syk_SYK_Y	P12318	FCGR2A	P43405	SYK	Y281	E282A	282	Missense	proximal	1	no	23.005	16.266	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	13.041	Down-regulation
TK_Syk_SYK_Y	P12318	FCGR2A	P43405	SYK	Y281	D280E	280	Missense	proximal	-1	no	23.005	21.334	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	13.041	Down-regulation
TK_Syk_SYK_Y	P12318	FCGR2A	P43405	SYK	Y281	T283A	283	Missense	proximal	2	no	23.005	21.909	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	13.041	Down-regulation
TK_Syk_SYK_Y	P12318	FCGR2A	P43405	SYK	Y281	G287S	287	Missense	distal	6	no	23.005	23.091	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	13.041	Up-regulation
TK_Syk_SYK_Y	P12318	FCGR2A	P43405	SYK	Y288	E282A	282	Missense	distal	-6	no	15.595	14.170	EPSD	TCGA;ICGC;COSMIC	13.041	Down-regulation
TK_Syk_SYK_Y	P12318	FCGR2A	P43405	SYK	Y288	T283A	283	Missense	distal	-5	no	15.595	15.217	EPSD	TCGA;ICGC;COSMIC	13.041	Down-regulation
TK_Syk_SYK_Y	P12318	FCGR2A	P43405	SYK	Y288	G287S	287	Missense	proximal	-1	no	15.595	16.941	EPSD	TCGA;ICGC;COSMIC	13.041	Up-regulation
TK_Syk_SYK_Y	P12318	FCGR2A	P43405	SYK	Y304	I303M	303	Missense	proximal	-1	no	15.344	15.326	PhosphoSitePlus;EPSD	TCGA;ICGC;COSMIC	13.041	Down-regulation
TK_Syk_SYK_Y	P12318	FCGR2A	P43405	SYK	Y304	D311H	311	Missense	distal	7	no	15.344	14.759	PhosphoSitePlus;EPSD	TCGA;ICGC;COSMIC	13.041	Down-regulation
TK_Syk_SYK_Y	P12318	FCGR2A	P43405	SYK	Y304	K301I	301	Missense	distal	-3	no	15.344	14.134	PhosphoSitePlus;EPSD	TCGA;ICGC;COSMIC	13.041	Down-regulation
TK_Syk_SYK_Y	P12318	FCGR2A	P43405	SYK	Y304	P308S	308	Missense	distal	4	no	15.344	15.287	PhosphoSitePlus;EPSD	TCGA;ICGC;COSMIC	13.041	Down-regulation
TK_Syk_SYK_Y	P12318	FCGR2A	P43405	SYK	Y304	D299Y	299	Missense	distal	-5	no	15.344	14.122	PhosphoSitePlus;EPSD	TCGA	13.041	Down-regulation
TK_Syk_SYK_Y	P13569	CFTR	P43405	SYK	Y512	S511F	511	Missense	proximal	-1	no	13.984	11.238	PhosphoSitePlus	TCGA;ICGC;COSMIC	13.041	Loss
TK_Syk_SYK_Y	P13569	CFTR	P43405	SYK	Y512	N505D	505	Missense	distal	-7	no	13.984	14.468	PhosphoSitePlus	TCGA;ICGC;COSMIC	13.041	Up-regulation
TK_Syk_SYK_Y	P13569	CFTR	P43405	SYK	Y1424	V1421E	1421	Missense	distal	-3	no	9.678	14.412	EPSD	TCGA;COSMIC	13.041	Gain
TK_Syk_SYK_Y	Q9GZY6	LAT2	P43405	SYK	Y40	I39S	39	Missense	proximal	-1	no	13.112	14.863	EPSD	TCGA;ICGC;COSMIC	13.041	Up-regulation
TK_Syk_SYK_Y	Q9GZY6	LAT2	P43405	SYK	Y110	P113H	113	Missense	distal	3	no	20.418	14.903	EPSD	TCGA;ICGC;COSMIC	13.041	Down-regulation
TK_Syk_SYK_Y	Q9GZY6	LAT2	P43405	SYK	Y136	D131E	131	Missense	distal	-5	no	21.870	21.691	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	13.041	Down-regulation
TK_Syk_SYK_Y	Q9GZY6	LAT2	P43405	SYK	Y233	A240D	240	Missense	distal	7	no	21.413	22.256	PhosphoSitePlus;EPSD	TCGA;ICGC;COSMIC	13.041	Up-regulation
TK_Syk_SYK_Y	Q9GZY6	LAT2	P43405	SYK	Y233	E226K	226	Missense	distal	-7	no	21.413	20.647	PhosphoSitePlus;EPSD	TCGA;ICGC	13.041	Down-regulation
TK_Syk_SYK_Y	Q14247	CTTN	P43405	SYK	Y215	Q216E	216	Missense	proximal	1	no	9.008	14.780	EPSD	TCGA;ICGC;COSMIC	13.041	Gain
TK_Syk_SYK_Y	Q14247	CTTN	P43405	SYK	Y228	G234E	234	Missense	distal	6	no	13.148	13.615	EPSD	TCGA;ICGC;COSMIC	13.041	Up-regulation
TK_Syk_SYK_Y	Q14247	CTTN	P43405	SYK	Y228	H222R	222	Missense	distal	-6	no	13.148	13.135	EPSD	TCGA;ICGC;COSMIC	13.041	Down-regulation
TK_Syk_SYK_Y	P52566	ARHGDIB	P43405	SYK	Y24	S31F	31	Missense	distal	7	no	17.657	16.961	PhosphoSitePlus	TCGA;ICGC;COSMIC	13.041	Down-regulation
TK_Syk_SYK_Y	P52566	ARHGDIB	P43405	SYK	Y146	Y146C	146	Missense	central	0	yes	13.420	0.000	EPSD	TCGA;ICGC;COSMIC	13.041	Loss
TK_Syk_SYK_Y	P52566	ARHGDIB	P43405	SYK	Y153	Y146C	146	Missense	distal	-7	no	14.241	14.048	EPSD	TCGA;ICGC;COSMIC	13.041	Down-regulation
TK_Syk_SYK_Y	P52566	ARHGDIB	P43405	SYK	Y153	E154D	154	Missense	proximal	1	no	14.241	10.601	EPSD	TCGA;ICGC;COSMIC	13.041	Loss
TK_Syk_SYK_Y	P52566	ARHGDIB	P43405	SYK	Y153	T157A	157	Missense	distal	4	no	14.241	14.076	EPSD	TCGA;ICGC;COSMIC	13.041	Down-regulation
TK_Syk_SYK_Y	P42229	STAT5A	P43405	SYK	Y694	Q698P	698	Missense	distal	4	no	15.261	15.552	PhosphoSitePlus	TCGA;ICGC	13.041	Up-regulation
TK_Syk_SYK_Y	P22681	CBL	P43405	SYK	Y141	R139I	139	Missense	proximal	-2	no	18.842	19.188	EPSD	TCGA;ICGC;COSMIC	13.041	Up-regulation
TK_Syk_SYK_Y	P22681	CBL	P43405	SYK	Y141	E143D	143	Missense	proximal	2	no	18.842	19.903	EPSD	TCGA;ICGC	13.041	Up-regulation
TK_Syk_SYK_Y	P22681	CBL	P43405	SYK	Y371	L370S	370	Missense	proximal	-1	no	9.832	14.171	EPSD	TCGA;ICGC	13.041	Gain
TK_Syk_SYK_Y	P22681	CBL	P43405	SYK	Y455	Y455N	455	Missense	central	0	yes	16.274	0.000	EPSD	TCGA	13.041	Loss
TK_Syk_SYK_Y	P22681	CBL	P43405	SYK	Y731	T730M	730	Missense	proximal	-1	no	19.225	17.912	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	13.041	Down-regulation
TK_Syk_SYK_Y	P22681	CBL	P43405	SYK	Y774	D772Y	772	Missense	proximal	-2	no	27.322	23.132	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	13.041	Down-regulation
TK_Syk_SYK_Y	P22681	CBL	P43405	SYK	Y774	D775V	775	Missense	proximal	1	no	27.322	27.241	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	13.041	Down-regulation
TK_Syk_SYK_Y	P37840	SNCA	P43405	SYK	Y125	P120S	120	Missense	distal	-5	no	26.604	26.993	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	13.041	Up-regulation
TK_Syk_SYK_Y	P37840	SNCA	P43405	SYK	Y125	S129F	129	Missense	distal	4	no	26.604	25.584	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	13.041	Down-regulation
TK_Syk_SYK_Y	P37840	SNCA	P43405	SYK	Y133	E137K	137	Missense	distal	4	no	19.060	18.656	PhosphoSitePlus;EPSD	TCGA;ICGC;COSMIC	13.041	Down-regulation
TK_Syk_SYK_Y	P37840	SNCA	P43405	SYK	Y133	D135Y	135	Missense	proximal	2	no	19.060	14.774	PhosphoSitePlus;EPSD	TCGA;ICGC;COSMIC	13.041	Down-regulation
TK_Syk_SYK_Y	P37840	SNCA	P43405	SYK	Y133	S129F	129	Missense	distal	-4	no	19.060	16.748	PhosphoSitePlus;EPSD	TCGA;ICGC;COSMIC	13.041	Down-regulation
TK_Syk_SYK_Y	P37840	SNCA	P43405	SYK	Y136	E137K	137	Missense	proximal	1	no	20.521	17.040	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	13.041	Down-regulation
TK_Syk_SYK_Y	P37840	SNCA	P43405	SYK	Y136	D135Y	135	Missense	proximal	-1	no	20.521	16.493	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	13.041	Down-regulation
TK_Syk_SYK_Y	P37840	SNCA	P43405	SYK	Y136	S129F	129	Missense	distal	-7	no	20.521	19.409	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	13.041	Down-regulation
TK_Syk_SYK_Y	P43405	SYK	P43405	SYK	Y28	E26K	26	Missense	proximal	-2	no	17.283	15.396	EPSD	TCGA;ICGC;COSMIC	13.041	Down-regulation
TK_Syk_SYK_Y	P43405	SYK	P43405	SYK	Y348	A353T	353	Missense	distal	5	no	25.445	25.356	EPSD;PhosphoSitePlus	TCGA;COSMIC;GDSC;CCLE	13.041	Down-regulation
TK_Syk_SYK_Y	P43405	SYK	P43405	SYK	Y348	T345R	345	Missense	distal	-3	no	25.445	23.770	EPSD;PhosphoSitePlus	TCGA;COSMIC	13.041	Down-regulation
TK_Syk_SYK_Y	P43405	SYK	P43405	SYK	Y348	D344G	344	Missense	distal	-4	no	25.445	22.969	EPSD;PhosphoSitePlus	TCGA;COSMIC	13.041	Down-regulation
TK_Syk_SYK_Y	P43405	SYK	P43405	SYK	Y352	E357Q	357	Missense	distal	5	no	19.592	19.866	PhosphoSitePlus;EPSD	TCGA	13.041	Up-regulation
TK_Syk_SYK_Y	P43405	SYK	P43405	SYK	Y352	A353T	353	Missense	proximal	1	no	19.592	20.970	PhosphoSitePlus;EPSD	TCGA;COSMIC;GDSC;CCLE	13.041	Up-regulation
TK_Syk_SYK_Y	P43405	SYK	P43405	SYK	Y352	T345R	345	Missense	distal	-7	no	19.592	19.485	PhosphoSitePlus;EPSD	TCGA;COSMIC	13.041	Down-regulation
TK_Syk_SYK_Y	P43405	SYK	P43405	SYK	Y364	E357Q	357	Missense	distal	-7	no	13.434	12.347	EPSD	TCGA	13.041	Loss
TK_Syk_SYK_Y	P43405	SYK	P43405	SYK	Y364	K361N	361	Missense	distal	-3	no	13.434	14.524	EPSD	TCGA;COSMIC	13.041	Up-regulation
TK_Syk_SYK_Y	P43405	SYK	P43405	SYK	Y364	T371M	371	Missense	distal	7	no	13.434	13.324	EPSD	TCGA;COSMIC	13.041	Down-regulation
TK_Syk_SYK_Y	P43405	SYK	P43405	SYK	Y364	E362K	362	Missense	proximal	-2	no	13.434	11.547	EPSD	TCGA;COSMIC	13.041	Loss
TK_Syk_SYK_Y	P43405	SYK	P43405	SYK	Y525	Q529H	529	Missense	distal	4	no	17.499	17.412	EPSD;PhosphoSitePlus	TCGA	13.041	Down-regulation
TK_Syk_SYK_Y	P43405	SYK	P43405	SYK	Y525	K527N	527	Missense	proximal	2	no	17.499	18.529	EPSD;PhosphoSitePlus	TCGA;COSMIC	13.041	Up-regulation
TK_Syk_SYK_Y	P43405	SYK	P43405	SYK	Y525	A521T	521	Missense	distal	-4	no	17.499	18.441	EPSD;PhosphoSitePlus	TCGA;COSMIC	13.041	Up-regulation
TK_Syk_SYK_Y	P43405	SYK	P43405	SYK	Y526	Q529H	529	Missense	distal	3	no	17.966	15.150	EPSD;PhosphoSitePlus	TCGA	13.041	Down-regulation
TK_Syk_SYK_Y	P43405	SYK	P43405	SYK	Y526	K527N	527	Missense	proximal	1	no	17.966	16.488	EPSD;PhosphoSitePlus	TCGA;COSMIC	13.041	Down-regulation
TK_Syk_SYK_Y	P43405	SYK	P43405	SYK	Y526	A521T	521	Missense	distal	-5	no	17.966	18.344	EPSD;PhosphoSitePlus	TCGA;COSMIC	13.041	Up-regulation
TK_Syk_SYK_Y	Q06187	BTK	P43405	SYK	Y551	D549N	549	Missense	proximal	-2	no	15.858	13.839	PhosphoSitePlus	TCGA;ICGC;COSMIC	13.041	Down-regulation
TK_Syk_SYK_Y	Q8N6F7	GCSAM	P43405	SYK	Y148	E149K	149	Missense	proximal	1	no	20.333	16.852	EPSD	TCGA;COSMIC	13.041	Down-regulation
TK_Syk_SYK_Y	Q8N6F7	GCSAM	P43405	SYK	Y148	E147K	147	Missense	proximal	-1	no	20.333	18.213	EPSD	TCGA;ICGC;COSMIC	13.041	Down-regulation
TK_Syk_SYK_Y	Q13094	LCP2	P43405	SYK	Y113	S115R	115	Missense	proximal	2	no	26.457	24.760	PhosphoSitePlus;EPSD	TCGA;ICGC;COSMIC	13.041	Down-regulation
TK_Syk_SYK_Y	Q13094	LCP2	P43405	SYK	Y113	E109D	109	Missense	distal	-4	no	26.457	27.734	PhosphoSitePlus;EPSD	TCGA;ICGC;COSMIC	13.041	Up-regulation
TK_Syk_SYK_Y	Q13094	LCP2	P43405	SYK	Y113	D111N	111	Missense	proximal	-2	no	26.457	24.438	PhosphoSitePlus;EPSD	TCGA;ICGC;COSMIC;GDSC;CCLE	13.041	Down-regulation
TK_Syk_SYK_Y	Q13094	LCP2	P43405	SYK	Y128	D127N	127	Missense	proximal	-1	no	32.230	30.740	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	13.041	Down-regulation
TK_Syk_SYK_Y	Q13094	LCP2	P43405	SYK	Y128	E123K	123	Missense	distal	-5	no	32.230	31.576	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	13.041	Down-regulation
TK_Syk_SYK_Y	Q13094	LCP2	P43405	SYK	Y128	N132S	132	Missense	distal	4	no	32.230	32.211	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	13.041	Down-regulation
TK_Syk_SYK_Y	Q13094	LCP2	P43405	SYK	Y128	G122V	122	Missense	distal	-6	no	32.230	32.094	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	13.041	Down-regulation
TK_Syk_SYK_Y	Q13094	LCP2	P43405	SYK	Y145	A143E	143	Missense	proximal	-2	no	28.463	32.011	EPSD	TCGA;ICGC	13.041	Up-regulation
TK_Syk_SYK_Y	Q13094	LCP2	P43405	SYK	Y145	V139M	139	Missense	distal	-6	no	28.463	28.277	EPSD	TCGA;ICGC;COSMIC;CCLE	13.041	Down-regulation
TK_Syk_SYK_Y	Q13094	LCP2	P43405	SYK	Y145	D144E	144	Missense	proximal	-1	no	28.463	26.792	EPSD	TCGA;ICGC;COSMIC	13.041	Down-regulation
TK_Syk_SYK_Y	Q13094	LCP2	P43405	SYK	Y173	D175Y	175	Missense	proximal	2	no	14.138	9.852	EPSD	TCGA;ICGC;COSMIC	13.041	Loss
TK_Syk_SYK_Y	Q13094	LCP2	P43405	SYK	Y173	Y173C	173	Missense	central	0	yes	14.138	0.000	EPSD	TCGA;ICGC	13.041	Loss
TK_Syk_SYK_Y	Q13094	LCP2	P43405	SYK	Y423	W422C	422	Missense	proximal	-1	no	18.723	19.436	EPSD	TCGA;ICGC;COSMIC	13.041	Up-regulation
TK_Syk_SYK_Y	Q13094	LCP2	P43405	SYK	Y459	P458L	458	Missense	proximal	-1	no	14.950	12.360	EPSD	TCGA;COSMIC	13.041	Loss
TK_Syk_SYK_Y	Q13094	LCP2	P43405	SYK	Y459	K466N	466	Missense	distal	7	no	14.950	15.066	EPSD	TCGA	13.041	Up-regulation
TK_Syk_SYK_Y	O14986	PIP5K1B	P43405	SYK	Y105	I109N	109	Missense	distal	4	no	16.430	16.888	PhosphoSitePlus	TCGA;ICGC;COSMIC	13.041	Up-regulation
STE_STE20_FRAY_STK39_ST	Q13621	SLC12A1	Q9UEW8	STK39	S91	A84T	84	Missense	distal	-7	no	87.080	86.122	EPSD	TCGA;ICGC;COSMIC	61.825	Down-regulation
STE_STE20_FRAY_STK39_ST	Q13621	SLC12A1	Q9UEW8	STK39	T95	F101C	101	Missense	distal	6	no	174.299	172.328	EPSD;PhosphoSitePlus	TCGA;ICGC	61.825	Down-regulation
STE_STE20_FRAY_STK39_ST	Q13621	SLC12A1	Q9UEW8	STK39	T100	D107N	107	Missense	distal	7	no	176.343	176.326	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	61.825	Down-regulation
STE_STE20_FRAY_STK39_ST	Q13621	SLC12A1	Q9UEW8	STK39	T100	N104K	104	Missense	distal	4	no	176.343	172.271	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	61.825	Down-regulation
STE_STE20_FRAY_STK39_ST	Q13621	SLC12A1	Q9UEW8	STK39	T100	F101C	101	Missense	proximal	1	no	176.343	162.122	EPSD;PhosphoSitePlus	TCGA;ICGC	61.825	Down-regulation
STE_STE20_FRAY_STK39_ST	Q13621	SLC12A1	Q9UEW8	STK39	T105	V109I	109	Missense	distal	4	no	157.976	155.854	PhosphoSitePlus;EPSD	TCGA;ICGC;COSMIC	61.825	Down-regulation
STE_STE20_FRAY_STK39_ST	Q13621	SLC12A1	Q9UEW8	STK39	T105	D107N	107	Missense	proximal	2	no	157.976	147.017	PhosphoSitePlus;EPSD	TCGA;ICGC;COSMIC	61.825	Down-regulation
STE_STE20_FRAY_STK39_ST	Q13621	SLC12A1	Q9UEW8	STK39	T105	N104K	104	Missense	proximal	-1	no	157.976	152.582	PhosphoSitePlus;EPSD	TCGA;ICGC;COSMIC	61.825	Down-regulation
STE_STE20_FRAY_STK39_ST	Q13621	SLC12A1	Q9UEW8	STK39	T105	F101C	101	Missense	distal	-4	no	157.976	150.126	PhosphoSitePlus;EPSD	TCGA;ICGC	61.825	Down-regulation
STE_STE20_FRAY_STK39_ST	Q13621	SLC12A1	Q9UEW8	STK39	T105	K111R	111	Missense	distal	6	no	157.976	156.752	PhosphoSitePlus;EPSD	TCGA;ICGC;COSMIC	61.825	Down-regulation
STE_STE20_FRAY_STK39_ST	Q13621	SLC12A1	Q9UEW8	STK39	T105	A108V	108	Missense	distal	3	no	157.976	157.277	PhosphoSitePlus;EPSD	TCGA;ICGC;COSMIC	61.825	Down-regulation
STE_STE20_FRAY_STK39_ST	Q13621	SLC12A1	Q9UEW8	STK39	T105	K111N	111	Missense	distal	6	no	157.976	156.122	PhosphoSitePlus;EPSD	TCGA;ICGC;COSMIC	61.825	Down-regulation
STE_STE20_FRAY_STK39_ST	Q13621	SLC12A1	Q9UEW8	STK39	S120	R116C	116	Missense	distal	-4	no	64.347	60.287	EPSD	TCGA;ICGC;COSMIC	61.825	Loss
STE_STE20_FRAY_STK39_ST	Q13621	SLC12A1	Q9UEW8	STK39	S120	P124H	124	Missense	distal	4	no	64.347	74.905	EPSD	TCGA;ICGC;COSMIC	61.825	Up-regulation
STE_STE20_FRAY_STK39_ST	Q13621	SLC12A1	Q9UEW8	STK39	S120	S120N	120	Missense	central	0	yes	64.347	0.000	EPSD	TCGA;ICGC;COSMIC	61.825	Loss
STE_STE20_FRAY_STK39_ST	Q13621	SLC12A1	Q9UEW8	STK39	S120	T118I	118	Missense	proximal	-2	no	64.347	60.404	EPSD	TCGA;ICGC;COSMIC	61.825	Loss
STE_STE20_FRAY_STK39_ST	Q13621	SLC12A1	Q9UEW8	STK39	T145	V152A	152	Missense	distal	7	no	90.681	90.663	EPSD	TCGA;ICGC;COSMIC	61.825	Down-regulation
STE_STE20_FRAY_STK39_ST	Q13621	SLC12A1	Q9UEW8	STK39	T145	T145I	145	Missense	central	0	yes	90.681	0.000	EPSD	TCGA;ICGC;COSMIC	61.825	Loss
STE_STE20_FRAY_STK39_ST	Q13621	SLC12A1	Q9UEW8	STK39	T882	H887Y	887	Missense	distal	5	no	131.807	121.519	EPSD	TCGA;ICGC;COSMIC	61.825	Down-regulation
STE_STE20_FRAY_STK39_ST	Q13621	SLC12A1	Q9UEW8	STK39	T882	V888A	888	Missense	distal	6	no	131.807	131.119	EPSD	TCGA;ICGC	61.825	Down-regulation
STE_STE20_FRAY_STK39_ST	Q13621	SLC12A1	Q9UEW8	STK39	S885	H887Y	887	Missense	proximal	2	no	62.500	49.772	EPSD	TCGA;ICGC;COSMIC	61.825	Loss
STE_STE20_FRAY_STK39_ST	Q13621	SLC12A1	Q9UEW8	STK39	S885	V888A	888	Missense	distal	3	no	62.500	63.199	EPSD	TCGA;ICGC	61.825	Up-regulation
STE_STE20_FRAY_STK39_ST	Q9Y6R1	SLC4A4	Q9UEW8	STK39	S38	R42K	42	Missense	distal	4	no	82.066	81.822	EPSD	TCGA;ICGC;COSMIC	61.825	Down-regulation
STE_STE20_FRAY_STK39_ST	Q9Y6R1	SLC4A4	Q9UEW8	STK39	S38	R43I	43	Missense	distal	5	no	82.066	91.423	EPSD	TCGA;ICGC;COSMIC	61.825	Up-regulation
STE_STE20_FRAY_STK39_ST	Q9Y6R1	SLC4A4	Q9UEW8	STK39	S38	P36L	36	Missense	proximal	-2	no	82.066	70.323	EPSD	TCGA;ICGC	61.825	Down-regulation
STE_STE20_FRAY_STK39_ST	Q9Y6R1	SLC4A4	Q9UEW8	STK39	T49	K54N	54	Missense	distal	5	no	94.930	90.469	EPSD	TCGA	61.825	Down-regulation
STE_STE20_FRAY_STK39_ST	Q9Y6R1	SLC4A4	Q9UEW8	STK39	T49	K48N	48	Missense	proximal	-1	no	94.930	100.324	EPSD	TCGA;ICGC;COSMIC	61.825	Up-regulation
STE_STE20_FRAY_STK39_ST	Q9Y6R1	SLC4A4	Q9UEW8	STK39	T49	R42K	42	Missense	distal	-7	no	94.930	93.717	EPSD	TCGA;ICGC;COSMIC	61.825	Down-regulation
STE_STE20_FRAY_STK39_ST	Q9Y6R1	SLC4A4	Q9UEW8	STK39	T49	R43I	43	Missense	distal	-6	no	94.930	69.434	EPSD	TCGA;ICGC;COSMIC	61.825	Down-regulation
STE_STE20_FRAY_STK39_ST	Q9Y6R1	SLC4A4	Q9UEW8	STK39	S65	Y64C	64	Missense	proximal	-1	no	113.053	107.189	PhosphoSitePlus	TCGA;ICGC;COSMIC	61.825	Down-regulation
STE_STE20_FRAY_STK39_ST	Q9Y6R1	SLC4A4	Q9UEW8	STK39	S65	E62D	62	Missense	distal	-3	no	113.053	115.912	PhosphoSitePlus	TCGA;ICGC;COSMIC	61.825	Up-regulation
STE_STE20_FRAY_STK39_ST	Q9Y6R1	SLC4A4	Q9UEW8	STK39	S65	S61Y	61	Missense	distal	-4	no	113.053	116.347	PhosphoSitePlus	TCGA;ICGC;COSMIC	61.825	Up-regulation
STE_STE20_FRAY_STK39_ST	Q9Y6R1	SLC4A4	Q9UEW8	STK39	S65	R59I	59	Missense	distal	-6	no	113.053	87.557	PhosphoSitePlus	TCGA;ICGC	61.825	Down-regulation
STE_STE20_FRAY_STK39_ST	Q9Y6R1	SLC4A4	Q9UEW8	STK39	T207	K203R	203	Missense	distal	-4	no	82.087	72.791	EPSD	TCGA;ICGC;COSMIC	61.825	Down-regulation
STE_STE20_FRAY_STK39_ST	Q9Y6R1	SLC4A4	Q9UEW8	STK39	T207	R210W	210	Missense	distal	3	no	82.087	80.827	EPSD	TCGA;ICGC;COSMIC	61.825	Down-regulation
STE_STE20_FRAY_STK39_ST	Q9Y6R1	SLC4A4	Q9UEW8	STK39	T230	S223F	223	Missense	distal	-7	no	77.218	78.177	EPSD	TCGA;ICGC;COSMIC	61.825	Up-regulation
STE_STE20_FRAY_STK39_ST	Q9Y6R1	SLC4A4	Q9UEW8	STK39	T230	K229E	229	Missense	proximal	-1	no	77.218	78.446	EPSD	TCGA;ICGC;COSMIC	61.825	Up-regulation
STE_STE20_FRAY_STK39_ST	Q9Y6R1	SLC4A4	Q9UEW8	STK39	T239	P246T	246	Missense	distal	7	no	65.823	65.828	EPSD	TCGA;ICGC;COSMIC	61.825	Up-regulation
STE_STE20_FRAY_STK39_ST	Q9Y6R1	SLC4A4	Q9UEW8	STK39	S245	P246T	246	Missense	proximal	1	no	86.181	68.085	EPSD	TCGA;ICGC;COSMIC	61.825	Down-regulation
STE_STE20_FRAY_STK39_ST	Q9Y6R1	SLC4A4	Q9UEW8	STK39	T249	P246T	246	Missense	distal	-3	no	77.158	74.827	EPSD	TCGA;ICGC;COSMIC	61.825	Down-regulation
STE_STE20_FRAY_STK39_ST	Q9Y6R1	SLC4A4	Q9UEW8	STK39	T254	S257C	257	Missense	distal	3	no	139.254	138.087	EPSD	TCGA;ICGC;COSMIC	61.825	Down-regulation
STE_STE20_FRAY_STK39_ST	Q9Y6R1	SLC4A4	Q9UEW8	STK39	S255	S257C	257	Missense	proximal	2	no	70.159	66.413	EPSD	TCGA;ICGC;COSMIC	61.825	Down-regulation
STE_STE20_FRAY_STK39_ST	Q9Y6R1	SLC4A4	Q9UEW8	STK39	S400	K404N	404	Missense	distal	4	no	59.785	63.858	EPSD	TCGA;ICGC;COSMIC;CCLE	61.825	Gain
STE_STE20_FRAY_STK39_ST	Q9Y6R1	SLC4A4	Q9UEW8	STK39	S1026	S1026I	1026	Missense	central	0	yes	98.211	0.000	EPSD	TCGA;ICGC;COSMIC	61.825	Loss
STE_STE20_FRAY_STK39_ST	Q9Y6R1	SLC4A4	Q9UEW8	STK39	S1026	D1030G	1030	Missense	distal	4	no	98.211	82.702	EPSD	TCGA;ICGC	61.825	Down-regulation
STE_STE20_FRAY_STK39_ST	P55011	SLC12A2	Q9UEW8	STK39	T266	G262R	262	Missense	distal	-4	no	65.275	68.786	EPSD	TCGA;ICGC;COSMIC	61.825	Up-regulation
STE_STE20_FRAY_STK39_ST	P55011	SLC12A2	Q9UEW8	STK39	T266	N261D	261	Missense	distal	-5	no	65.275	81.355	EPSD	TCGA;ICGC;COSMIC	61.825	Up-regulation
STE_STE20_FRAY_STK39_ST	P55011	SLC12A2	Q9UEW8	STK39	T266	T266A	266	Missense	central	0	yes	65.275	0.000	EPSD	TCGA;ICGC;COSMIC	61.825	Loss
STE_STE20_FRAY_STK39_ST	P55011	SLC12A2	Q9UEW8	STK39	T268	G262R	262	Missense	distal	-6	no	57.823	78.911	EPSD	TCGA;ICGC;COSMIC	61.825	Gain
STE_STE20_FRAY_STK39_ST	P55011	SLC12A2	Q9UEW8	STK39	S953	K958I	958	Missense	distal	5	no	61.947	59.781	EPSD	TCGA;ICGC;COSMIC	61.825	Loss
STE_STE20_FRAY_STK39_ST	P55011	SLC12A2	Q9UEW8	STK39	T964	D961N	961	Missense	distal	-3	no	84.888	83.512	EPSD	TCGA;ICGC;COSMIC	61.825	Down-regulation
STE_STE20_FRAY_STK39_ST	P55011	SLC12A2	Q9UEW8	STK39	T964	D961Y	961	Missense	distal	-3	no	84.888	85.347	EPSD	TCGA;ICGC;COSMIC	61.825	Up-regulation
STE_STE20_FRAY_STK39_ST	P55011	SLC12A2	Q9UEW8	STK39	T964	K958I	958	Missense	distal	-6	no	84.888	73.270	EPSD	TCGA;ICGC;COSMIC	61.825	Down-regulation
STE_STE20_FRAY_STK39_ST	P55011	SLC12A2	Q9UEW8	STK39	T986	E993D	993	Missense	distal	7	no	101.283	101.305	EPSD	TCGA;ICGC;COSMIC	61.825	Up-regulation
STE_STE20_FRAY_STK39_ST	P55011	SLC12A2	Q9UEW8	STK39	T1144	E1140Q	1140	Missense	distal	-4	no	56.179	67.159	EPSD	TCGA;ICGC;COSMIC;GDSC;CCLE	61.825	Gain
STE_STE20_FRAY_STK39_ST	Q9H2X9	SLC12A5	Q9UEW8	STK39	S54	E58K	58	Missense	distal	4	no	63.461	65.471	EPSD	TCGA;ICGC;COSMIC	61.825	Up-regulation
STE_STE20_FRAY_STK39_ST	Q9H2X9	SLC12A5	Q9UEW8	STK39	S54	K59N	59	Missense	distal	5	no	63.461	59.000	EPSD	TCGA;COSMIC	61.825	Loss
STE_STE20_FRAY_STK39_ST	Q9H2X9	SLC12A5	Q9UEW8	STK39	S54	E47K	47	Missense	distal	-7	no	63.461	61.778	EPSD	TCGA;ICGC;COSMIC	61.825	Loss
STE_STE20_FRAY_STK39_ST	Q9H2X9	SLC12A5	Q9UEW8	STK39	S54	P50S	50	Missense	distal	-4	no	63.461	60.213	EPSD	TCGA;ICGC;COSMIC	61.825	Loss
STE_STE20_FRAY_STK39_ST	Q9H2X9	SLC12A5	Q9UEW8	STK39	S54	E58D	58	Missense	distal	4	no	63.461	72.643	EPSD	TCGA;ICGC;COSMIC	61.825	Up-regulation
STE_STE20_FRAY_STK39_ST	Q9H2X9	SLC12A5	Q9UEW8	STK39	S54	S54N	54	Missense	central	0	yes	63.461	0.000	EPSD	TCGA;ICGC;COSMIC	61.825	Loss
STE_STE20_FRAY_STK39_ST	Q9H2X9	SLC12A5	Q9UEW8	STK39	T92	N93Y	93	Missense	proximal	1	no	54.286	67.123	EPSD	TCGA;COSMIC	61.825	Gain
STE_STE20_FRAY_STK39_ST	Q9H2X9	SLC12A5	Q9UEW8	STK39	T335	T335M	335	Missense	central	0	yes	80.046	0.000	EPSD	TCGA;COSMIC	61.825	Loss
STE_STE20_FRAY_STK39_ST	Q9H2X9	SLC12A5	Q9UEW8	STK39	T335	G332E	332	Missense	distal	-3	no	80.046	79.526	EPSD	TCGA;COSMIC	61.825	Down-regulation
STE_STE20_FRAY_STK39_ST	Q9H2X9	SLC12A5	Q9UEW8	STK39	T335	G332R	332	Missense	distal	-3	no	80.046	82.728	EPSD	TCGA;COSMIC	61.825	Up-regulation
STE_STE20_FRAY_STK39_ST	Q9H2X9	SLC12A5	Q9UEW8	STK39	T335	R339Q	339	Missense	distal	4	no	80.046	74.353	EPSD	TCGA;COSMIC	61.825	Down-regulation
STE_STE20_FRAY_STK39_ST	Q9H2X9	SLC12A5	Q9UEW8	STK39	T335	T338A	338	Missense	distal	3	no	80.046	79.949	EPSD	TCGA;COSMIC	61.825	Down-regulation
STE_STE20_FRAY_STK39_ST	Q9H2X9	SLC12A5	Q9UEW8	STK39	T335	E334Q	334	Missense	proximal	-1	no	80.046	80.897	EPSD	TCGA;COSMIC	61.825	Up-regulation
STE_STE20_FRAY_STK39_ST	Q9H2X9	SLC12A5	Q9UEW8	STK39	T1030	E1025D	1025	Missense	distal	-5	no	116.173	147.679	EPSD	TCGA;ICGC;COSMIC	61.825	Up-regulation
STE_STE20_FRAY_STK39_ST	Q9H2X9	SLC12A5	Q9UEW8	STK39	T1032	A1038T	1038	Missense	distal	6	no	134.520	134.738	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	61.825	Up-regulation
STE_STE20_FRAY_STK39_ST	Q9H2X9	SLC12A5	Q9UEW8	STK39	T1032	E1025D	1025	Missense	distal	-7	no	134.520	132.703	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	61.825	Down-regulation
STE_STE20_FRAY_STK39_ST	Q9H2X9	SLC12A5	Q9UEW8	STK39	S1045	P1044L	1044	Missense	proximal	-1	no	75.757	73.779	EPSD	TCGA;ICGC;COSMIC	61.825	Down-regulation
STE_STE20_FRAY_STK39_ST	Q9H2X9	SLC12A5	Q9UEW8	STK39	S1045	A1038T	1038	Missense	distal	-7	no	75.757	74.799	EPSD	TCGA;ICGC;COSMIC	61.825	Down-regulation
STE_STE20_FRAY_STK39_ST	Q9H2X9	SLC12A5	Q9UEW8	STK39	S1045	S1048F	1048	Missense	distal	3	no	75.757	75.057	EPSD	TCGA;ICGC;COSMIC	61.825	Down-regulation
STE_STE20_FRAY_STK39_ST	Q9H2X9	SLC12A5	Q9UEW8	STK39	S1045	S1045N	1045	Missense	central	0	yes	75.757	0.000	EPSD	TCGA;ICGC	61.825	Loss
STE_STE20_FRAY_STK39_ST	Q9Y666	SLC12A7	Q9UEW8	STK39	T958	R956W	956	Missense	proximal	-2	no	81.330	77.712	EPSD	TCGA;ICGC;COSMIC	61.825	Down-regulation
STE_STE20_FRAY_STK39_ST	Q9Y666	SLC12A7	Q9UEW8	STK39	T958	A959V	959	Missense	proximal	1	no	81.330	98.121	EPSD	TCGA;ICGC;COSMIC;GDSC	61.825	Up-regulation
STE_STE20_FRAY_STK39_ST	Q9Y666	SLC12A7	Q9UEW8	STK39	T958	A959T	959	Missense	proximal	1	no	81.330	90.768	EPSD	TCGA;ICGC;COSMIC;CCLE	61.825	Up-regulation
STE_STE20_FRAY_STK39_ST	Q9Y666	SLC12A7	Q9UEW8	STK39	S960	R956W	956	Missense	distal	-4	no	72.283	72.074	EPSD	TCGA;ICGC;COSMIC	61.825	Down-regulation
STE_STE20_FRAY_STK39_ST	Q9Y666	SLC12A7	Q9UEW8	STK39	S960	A959V	959	Missense	proximal	-1	no	72.283	74.843	EPSD	TCGA;ICGC;COSMIC;GDSC	61.825	Up-regulation
STE_STE20_FRAY_STK39_ST	Q9Y666	SLC12A7	Q9UEW8	STK39	S960	A959T	959	Missense	proximal	-1	no	72.283	75.175	EPSD	TCGA;ICGC;COSMIC;CCLE	61.825	Up-regulation
STE_STE20_FRAY_STK39_ST	Q9Y666	SLC12A7	Q9UEW8	STK39	T962	R956W	956	Missense	distal	-6	no	71.316	53.947	EPSD	TCGA;ICGC;COSMIC	61.825	Loss
STE_STE20_FRAY_STK39_ST	Q9Y666	SLC12A7	Q9UEW8	STK39	T962	A959V	959	Missense	distal	-3	no	71.316	72.020	EPSD	TCGA;ICGC;COSMIC;GDSC	61.825	Up-regulation
STE_STE20_FRAY_STK39_ST	Q9Y666	SLC12A7	Q9UEW8	STK39	T962	A959T	959	Missense	distal	-3	no	71.316	72.974	EPSD	TCGA;ICGC;COSMIC;CCLE	61.825	Up-regulation
STE_STE20_FRAY_STK39_ST	Q9Y666	SLC12A7	Q9UEW8	STK39	T973	A970V	970	Missense	distal	-3	no	142.688	143.392	PhosphoSitePlus;EPSD	TCGA;ICGC;COSMIC	61.825	Up-regulation
STE_STE20_FRAY_STK39_ST	Q9Y666	SLC12A7	Q9UEW8	STK39	T980	W981C	981	Missense	proximal	1	no	144.176	131.793	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	61.825	Down-regulation
STE_STE20_FRAY_STK39_ST	Q9Y666	SLC12A7	Q9UEW8	STK39	T982	A988P	988	Missense	distal	6	no	67.085	69.926	EPSD	TCGA;ICGC;COSMIC	61.825	Up-regulation
STE_STE20_FRAY_STK39_ST	Q9Y666	SLC12A7	Q9UEW8	STK39	T982	W981C	981	Missense	proximal	-1	no	67.085	61.508	EPSD	TCGA;ICGC;COSMIC	61.825	Loss
STE_STE20_FRAY_STK39_ST	Q9Y666	SLC12A7	Q9UEW8	STK39	T982	A988T	988	Missense	distal	6	no	67.085	67.303	EPSD	TCGA;ICGC;COSMIC	61.825	Up-regulation
STE_STE20_FRAY_STK39_ST	Q9UHW9	SLC12A6	Q9UEW8	STK39	T18	F15L	15	Missense	distal	-3	no	108.850	104.090	EPSD	TCGA;ICGC;COSMIC	61.825	Down-regulation
STE_STE20_FRAY_STK39_ST	Q9UHW9	SLC12A6	Q9UEW8	STK39	T18	D24A	24	Missense	distal	6	no	108.850	107.691	EPSD	TCGA;COSMIC	61.825	Down-regulation
STE_STE20_FRAY_STK39_ST	Q9UHW9	SLC12A6	Q9UEW8	STK39	T18	D24H	24	Missense	distal	6	no	108.850	109.960	EPSD	TCGA;ICGC;COSMIC	61.825	Up-regulation
STE_STE20_FRAY_STK39_ST	Q9UHW9	SLC12A6	Q9UEW8	STK39	T18	R14Q	14	Missense	distal	-4	no	108.850	111.394	EPSD	TCGA;ICGC;COSMIC	61.825	Up-regulation
STE_STE20_FRAY_STK39_ST	Q9UHW9	SLC12A6	Q9UEW8	STK39	T18	D23N	23	Missense	distal	5	no	108.850	96.676	EPSD	TCGA;ICGC	61.825	Down-regulation
STE_STE20_FRAY_STK39_ST	Q9UHW9	SLC12A6	Q9UEW8	STK39	T20	F15L	15	Missense	distal	-5	no	92.495	79.196	EPSD	TCGA;ICGC;COSMIC	61.825	Down-regulation
STE_STE20_FRAY_STK39_ST	Q9UHW9	SLC12A6	Q9UEW8	STK39	T20	D24A	24	Missense	distal	4	no	92.495	74.658	EPSD	TCGA;COSMIC	61.825	Down-regulation
STE_STE20_FRAY_STK39_ST	Q9UHW9	SLC12A6	Q9UEW8	STK39	T20	D24H	24	Missense	distal	4	no	92.495	90.591	EPSD	TCGA;ICGC;COSMIC	61.825	Down-regulation
STE_STE20_FRAY_STK39_ST	Q9UHW9	SLC12A6	Q9UEW8	STK39	T20	I25M	25	Missense	distal	5	no	92.495	89.586	EPSD	TCGA;COSMIC	61.825	Down-regulation
STE_STE20_FRAY_STK39_ST	Q9UHW9	SLC12A6	Q9UEW8	STK39	T20	R14Q	14	Missense	distal	-6	no	92.495	78.208	EPSD	TCGA;ICGC;COSMIC	61.825	Down-regulation
STE_STE20_FRAY_STK39_ST	Q9UHW9	SLC12A6	Q9UEW8	STK39	T20	D23N	23	Missense	distal	3	no	92.495	92.471	EPSD	TCGA;ICGC	61.825	Down-regulation
STE_STE20_FRAY_STK39_ST	Q9UHW9	SLC12A6	Q9UEW8	STK39	S29	D24A	24	Missense	distal	-5	no	73.880	30.365	EPSD	TCGA;COSMIC	61.825	Loss
STE_STE20_FRAY_STK39_ST	Q9UHW9	SLC12A6	Q9UEW8	STK39	S29	D24H	24	Missense	distal	-5	no	73.880	64.460	EPSD	TCGA;ICGC;COSMIC	61.825	Down-regulation
STE_STE20_FRAY_STK39_ST	Q9UHW9	SLC12A6	Q9UEW8	STK39	S29	I25M	25	Missense	distal	-4	no	73.880	77.199	EPSD	TCGA;COSMIC	61.825	Up-regulation
STE_STE20_FRAY_STK39_ST	Q9UHW9	SLC12A6	Q9UEW8	STK39	S29	S36R	36	Missense	distal	7	no	73.880	73.878	EPSD	TCGA;ICGC;COSMIC	61.825	Down-regulation
STE_STE20_FRAY_STK39_ST	Q9UHW9	SLC12A6	Q9UEW8	STK39	S29	D23N	23	Missense	distal	-6	no	73.880	83.509	EPSD	TCGA;ICGC	61.825	Up-regulation
STE_STE20_FRAY_STK39_ST	Q9UHW9	SLC12A6	Q9UEW8	STK39	T31	I25M	25	Missense	distal	-6	no	51.443	63.285	EPSD	TCGA;COSMIC	61.825	Gain
STE_STE20_FRAY_STK39_ST	Q9UHW9	SLC12A6	Q9UEW8	STK39	T54	S57N	57	Missense	distal	3	no	71.164	70.792	EPSD	TCGA	61.825	Down-regulation
STE_STE20_FRAY_STK39_ST	Q9UHW9	SLC12A6	Q9UEW8	STK39	T67	G65R	65	Missense	proximal	-2	no	53.674	65.151	EPSD	TCGA;COSMIC	61.825	Gain
STE_STE20_FRAY_STK39_ST	Q9UHW9	SLC12A6	Q9UEW8	STK39	T68	A66V	66	Missense	proximal	-2	no	72.709	77.953	EPSD	TCGA;COSMIC	61.825	Up-regulation
STE_STE20_FRAY_STK39_ST	Q9UHW9	SLC12A6	Q9UEW8	STK39	T68	G65R	65	Missense	distal	-3	no	72.709	75.390	EPSD	TCGA;COSMIC	61.825	Up-regulation
STE_STE20_FRAY_STK39_ST	Q9UHW9	SLC12A6	Q9UEW8	STK39	T72	A66V	66	Missense	distal	-6	no	81.995	72.853	EPSD	TCGA;COSMIC	61.825	Down-regulation
STE_STE20_FRAY_STK39_ST	Q9UHW9	SLC12A6	Q9UEW8	STK39	T72	G65R	65	Missense	distal	-7	no	81.995	81.521	EPSD	TCGA;COSMIC	61.825	Down-regulation
STE_STE20_FRAY_STK39_ST	Q9UHW9	SLC12A6	Q9UEW8	STK39	S96	S96P	96	Missense	central	0	yes	125.264	0.000	EPSD;PhosphoSitePlus	TCGA;COSMIC	61.825	Loss
STE_STE20_FRAY_STK39_ST	Q9UHW9	SLC12A6	Q9UEW8	STK39	T157	R152C	152	Missense	distal	-5	no	55.144	67.080	EPSD	TCGA;COSMIC	61.825	Gain
STE_STE20_FRAY_STK39_ST	Q9UHW9	SLC12A6	Q9UEW8	STK39	T187	Y192C	192	Missense	distal	5	no	72.686	67.126	EPSD	TCGA;COSMIC	61.825	Down-regulation
STE_STE20_FRAY_STK39_ST	Q9UHW9	SLC12A6	Q9UEW8	STK39	T187	T187I	187	Missense	central	0	yes	72.686	0.000	EPSD	TCGA;COSMIC	61.825	Loss
STE_STE20_FRAY_STK39_ST	Q9UHW9	SLC12A6	Q9UEW8	STK39	T1028	R1026P	1026	Missense	proximal	-2	no	102.031	100.410	EPSD	TCGA;COSMIC	61.825	Down-regulation
STE_STE20_FRAY_STK39_ST	Q9UHW9	SLC12A6	Q9UEW8	STK39	T1038	E1036K	1036	Missense	proximal	-2	no	93.526	105.264	EPSD	TCGA;COSMIC	61.825	Up-regulation
STE_STE20_FRAY_STK39_ST	Q9UHW9	SLC12A6	Q9UEW8	STK39	T1040	E1036K	1036	Missense	distal	-4	no	97.170	114.902	EPSD	TCGA;COSMIC	61.825	Up-regulation
STE_STE20_FRAY_STK39_ST	Q9UHW9	SLC12A6	Q9UEW8	STK39	T1086	R1083W	1083	Missense	distal	-3	no	66.052	65.387	EPSD	TCGA	61.825	Down-regulation
STE_STE20_FRAY_STK39_ST	Q9UP95	SLC12A4	Q9UEW8	STK39	T983	T985M	985	Missense	proximal	2	no	176.865	165.460	PhosphoSitePlus;EPSD	TCGA;COSMIC	61.825	Down-regulation
STE_STE20_FRAY_STK39_ST	Q9UP95	SLC12A4	Q9UEW8	STK39	T985	T985M	985	Missense	central	0	yes	90.002	0.000	EPSD	TCGA;COSMIC	61.825	Loss
STE_STE20_FRAY_STK39_ST	Q9UP95	SLC12A4	Q9UEW8	STK39	T991	T985M	985	Missense	distal	-6	no	98.365	104.722	EPSD	TCGA;COSMIC	61.825	Up-regulation
STE_STE20_FRAY_STK39_ST	P55017	SLC12A3	Q9UEW8	STK39	T14	R19C	19	Missense	distal	5	no	75.566	79.578	EPSD	TCGA;ICGC;COSMIC	61.825	Up-regulation
STE_STE20_FRAY_STK39_ST	P55017	SLC12A3	Q9UEW8	STK39	T46	P42L	42	Missense	distal	-4	no	151.632	130.267	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	61.825	Down-regulation
STE_STE20_FRAY_STK39_ST	P55017	SLC12A3	Q9UEW8	STK39	T46	T50A	50	Missense	distal	4	no	151.632	136.157	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	61.825	Down-regulation
STE_STE20_FRAY_STK39_ST	P55017	SLC12A3	Q9UEW8	STK39	T46	S39N	39	Missense	distal	-7	no	151.632	151.426	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	61.825	Down-regulation
STE_STE20_FRAY_STK39_ST	P55017	SLC12A3	Q9UEW8	STK39	T50	R54C	54	Missense	distal	4	no	82.847	76.609	EPSD	TCGA;ICGC;COSMIC	61.825	Down-regulation
STE_STE20_FRAY_STK39_ST	P55017	SLC12A3	Q9UEW8	STK39	T50	T50A	50	Missense	central	0	yes	82.847	0.000	EPSD	TCGA;ICGC;COSMIC	61.825	Loss
STE_STE20_FRAY_STK39_ST	P55017	SLC12A3	Q9UEW8	STK39	T55	R54C	54	Missense	proximal	-1	no	164.354	153.219	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	61.825	Down-regulation
STE_STE20_FRAY_STK39_ST	P55017	SLC12A3	Q9UEW8	STK39	T55	T50A	50	Missense	distal	-5	no	164.354	121.839	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	61.825	Down-regulation
STE_STE20_FRAY_STK39_ST	P55017	SLC12A3	Q9UEW8	STK39	T55	D62N	62	Missense	distal	7	no	164.354	164.336	EPSD;PhosphoSitePlus	TCGA;ICGC	61.825	Down-regulation
STE_STE20_FRAY_STK39_ST	P55017	SLC12A3	Q9UEW8	STK39	T60	R54C	54	Missense	distal	-6	no	159.444	136.866	PhosphoSitePlus;EPSD	TCGA;ICGC;COSMIC	61.825	Down-regulation
STE_STE20_FRAY_STK39_ST	P55017	SLC12A3	Q9UEW8	STK39	T60	V63L	63	Missense	distal	3	no	159.444	158.604	PhosphoSitePlus;EPSD	TCGA;ICGC;COSMIC	61.825	Down-regulation
STE_STE20_FRAY_STK39_ST	P55017	SLC12A3	Q9UEW8	STK39	T60	D62N	62	Missense	proximal	2	no	159.444	148.485	PhosphoSitePlus;EPSD	TCGA;ICGC	61.825	Down-regulation
STE_STE20_FRAY_STK39_ST	P55017	SLC12A3	Q9UEW8	STK39	T66	E68Q	68	Missense	proximal	2	no	69.898	68.154	EPSD	TCGA	61.825	Down-regulation
STE_STE20_FRAY_STK39_ST	P55017	SLC12A3	Q9UEW8	STK39	T66	V63L	63	Missense	distal	-3	no	69.898	66.335	EPSD	TCGA;ICGC;COSMIC	61.825	Down-regulation
STE_STE20_FRAY_STK39_ST	P55017	SLC12A3	Q9UEW8	STK39	T66	E68K	68	Missense	proximal	2	no	69.898	79.180	EPSD	TCGA;ICGC;COSMIC	61.825	Up-regulation
STE_STE20_FRAY_STK39_ST	P55017	SLC12A3	Q9UEW8	STK39	T66	D62N	62	Missense	distal	-4	no	69.898	63.334	EPSD	TCGA;ICGC	61.825	Down-regulation
STE_STE20_FRAY_STK39_ST	P55017	SLC12A3	Q9UEW8	STK39	T74	E68Q	68	Missense	distal	-6	no	101.488	101.533	EPSD	TCGA	61.825	Up-regulation
STE_STE20_FRAY_STK39_ST	P55017	SLC12A3	Q9UEW8	STK39	T74	R80Q	80	Missense	distal	6	no	101.488	101.388	EPSD	TCGA;ICGC;COSMIC	61.825	Down-regulation
STE_STE20_FRAY_STK39_ST	P55017	SLC12A3	Q9UEW8	STK39	T74	R80W	80	Missense	distal	6	no	101.488	101.690	EPSD	TCGA;ICGC;COSMIC	61.825	Up-regulation
STE_STE20_FRAY_STK39_ST	P55017	SLC12A3	Q9UEW8	STK39	T74	E68K	68	Missense	distal	-6	no	101.488	101.943	EPSD	TCGA;ICGC;COSMIC	61.825	Up-regulation
STE_STE20_FRAY_STK39_ST	P55017	SLC12A3	Q9UEW8	STK39	T85	R80Q	80	Missense	distal	-5	no	60.708	69.620	EPSD	TCGA;ICGC;COSMIC	61.825	Gain
STE_STE20_FRAY_STK39_ST	P55017	SLC12A3	Q9UEW8	STK39	T85	R80W	80	Missense	distal	-5	no	60.708	72.845	EPSD	TCGA;ICGC;COSMIC	61.825	Gain
STE_STE20_FRAY_STK39_ST	P55017	SLC12A3	Q9UEW8	STK39	T753	A752T	752	Missense	proximal	-1	no	63.580	66.471	EPSD	TCGA;ICGC;COSMIC	61.825	Up-regulation
STE_STE20_FRAY_STK39_ST	P55017	SLC12A3	Q9UEW8	STK39	T753	Q747E	747	Missense	distal	-6	no	63.580	63.535	EPSD	TCGA;COSMIC	61.825	Down-regulation
TKL_IRAK_IRAK1_ST	Q96FA3	PELI1	P51617	IRAK1	S70	S70G	70	Missense	central	0	yes	121.890	0.000	EPSD;PhosphoSitePlus	TCGA;ICGC	67.712	Loss
TKL_IRAK_IRAK1_ST	Q96FA3	PELI1	P51617	IRAK1	S76	S78L	78	Missense	proximal	2	no	121.388	111.122	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	67.712	Down-regulation
TKL_IRAK_IRAK1_ST	Q96FA3	PELI1	P51617	IRAK1	S76	Y79H	79	Missense	distal	3	no	121.388	119.740	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	67.712	Down-regulation
TKL_IRAK_IRAK1_ST	Q96FA3	PELI1	P51617	IRAK1	S76	S70G	70	Missense	distal	-6	no	121.388	109.257	EPSD;PhosphoSitePlus	TCGA;ICGC	67.712	Down-regulation
TKL_IRAK_IRAK1_ST	Q96FA3	PELI1	P51617	IRAK1	S78	S78L	78	Missense	central	0	yes	133.451	0.000	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	67.712	Loss
TKL_IRAK_IRAK1_ST	Q96FA3	PELI1	P51617	IRAK1	S78	Y79H	79	Missense	proximal	1	no	133.451	133.471	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	67.712	Up-regulation
TKL_IRAK_IRAK1_ST	Q96FA3	PELI1	P51617	IRAK1	S78	Q85H	85	Missense	distal	7	no	133.451	136.854	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	67.712	Up-regulation
TKL_IRAK_IRAK1_ST	Q96FA3	PELI1	P51617	IRAK1	T80	V87L	87	Missense	distal	7	no	113.437	102.540	PhosphoSitePlus;EPSD	TCGA;ICGC;COSMIC	67.712	Down-regulation
TKL_IRAK_IRAK1_ST	Q96FA3	PELI1	P51617	IRAK1	T80	S78L	78	Missense	proximal	-2	no	113.437	113.188	PhosphoSitePlus;EPSD	TCGA;ICGC;COSMIC	67.712	Down-regulation
TKL_IRAK_IRAK1_ST	Q96FA3	PELI1	P51617	IRAK1	T80	Y79H	79	Missense	proximal	-1	no	113.437	112.572	PhosphoSitePlus;EPSD	TCGA;ICGC;COSMIC	67.712	Down-regulation
TKL_IRAK_IRAK1_ST	Q96FA3	PELI1	P51617	IRAK1	T80	Q85H	85	Missense	distal	5	no	113.437	114.822	PhosphoSitePlus;EPSD	TCGA;ICGC;COSMIC	67.712	Up-regulation
TKL_IRAK_IRAK1_ST	Q96FA3	PELI1	P51617	IRAK1	S82	V87L	87	Missense	distal	5	no	122.719	124.480	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	67.712	Up-regulation
TKL_IRAK_IRAK1_ST	Q96FA3	PELI1	P51617	IRAK1	S82	V89F	89	Missense	distal	7	no	122.719	103.437	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	67.712	Down-regulation
TKL_IRAK_IRAK1_ST	Q96FA3	PELI1	P51617	IRAK1	S82	S78L	78	Missense	distal	-4	no	122.719	116.604	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	67.712	Down-regulation
TKL_IRAK_IRAK1_ST	Q96FA3	PELI1	P51617	IRAK1	S82	Y79H	79	Missense	distal	-3	no	122.719	122.487	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	67.712	Down-regulation
TKL_IRAK_IRAK1_ST	Q96FA3	PELI1	P51617	IRAK1	S82	Q85H	85	Missense	distal	3	no	122.719	119.190	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	67.712	Down-regulation
TKL_IRAK_IRAK1_ST	Q96FA3	PELI1	P51617	IRAK1	T86	V87L	87	Missense	proximal	1	no	110.913	112.785	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	67.712	Up-regulation
TKL_IRAK_IRAK1_ST	Q96FA3	PELI1	P51617	IRAK1	T86	V89F	89	Missense	distal	3	no	110.913	107.074	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	67.712	Down-regulation
TKL_IRAK_IRAK1_ST	Q96FA3	PELI1	P51617	IRAK1	T86	Y79H	79	Missense	distal	-7	no	110.913	113.245	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	67.712	Up-regulation
TKL_IRAK_IRAK1_ST	Q96FA3	PELI1	P51617	IRAK1	T86	Q85H	85	Missense	proximal	-1	no	110.913	111.946	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	67.712	Up-regulation
TKL_IRAK_IRAK1_ST	Q96FA3	PELI1	P51617	IRAK1	T288	P283H	283	Missense	distal	-5	no	130.428	136.041	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	67.712	Up-regulation
TKL_IRAK_IRAK1_ST	Q96FA3	PELI1	P51617	IRAK1	S293	V299I	299	Missense	distal	6	no	116.243	111.895	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC;CCLE	67.712	Down-regulation
TKL_IRAK_IRAK1_ST	P51617	IRAK1	P51617	IRAK1	T113	P111S	111	Missense	proximal	-2	no	81.507	81.219	EPSD	TCGA;COSMIC	67.712	Down-regulation
TKL_IRAK_IRAK1_ST	P51617	IRAK1	P51617	IRAK1	T113	P109S	109	Missense	distal	-4	no	81.507	82.223	EPSD	TCGA;COSMIC;CCLE	67.712	Up-regulation
TKL_IRAK_IRAK1_ST	P51617	IRAK1	P51617	IRAK1	S119	E126D	126	Missense	distal	7	no	77.258	73.806	EPSD	TCGA;COSMIC	67.712	Down-regulation
TKL_IRAK_IRAK1_ST	P51617	IRAK1	P51617	IRAK1	S131	E126D	126	Missense	distal	-5	no	80.572	81.432	EPSD	TCGA;COSMIC	67.712	Up-regulation
TKL_IRAK_IRAK1_ST	P51617	IRAK1	P51617	IRAK1	T209	G208D	208	Missense	proximal	-1	no	117.499	113.953	EPSD;PhosphoSitePlus	TCGA;COSMIC	67.712	Down-regulation
TKL_IRAK_IRAK1_ST	P51617	IRAK1	P51617	IRAK1	T381	S376R	376	Missense	distal	-5	no	80.256	81.449	EPSD	TCGA	67.712	Up-regulation
TKL_IRAK_IRAK1_ST	P51617	IRAK1	P51617	IRAK1	T381	L388M	388	Missense	distal	7	no	80.256	77.918	EPSD	TCGA;COSMIC	67.712	Down-regulation
TKL_IRAK_IRAK1_ST	P51617	IRAK1	P51617	IRAK1	T387	T381S	381	Missense	distal	-6	no	112.578	103.773	PhosphoSitePlus;EPSD	TCGA;COSMIC	67.712	Down-regulation
TKL_IRAK_IRAK1_ST	P51617	IRAK1	P51617	IRAK1	T387	L391V	391	Missense	distal	4	no	112.578	116.584	PhosphoSitePlus;EPSD	TCGA	67.712	Up-regulation
TKL_IRAK_IRAK1_ST	P51617	IRAK1	P51617	IRAK1	T387	L388M	388	Missense	proximal	1	no	112.578	112.271	PhosphoSitePlus;EPSD	TCGA;COSMIC	67.712	Down-regulation
TKL_IRAK_IRAK1_ST	Q9HAT8	PELI2	P51617	IRAK1	S78	I71M	71	Missense	distal	-7	no	72.191	72.251	EPSD	TCGA;ICGC;COSMIC	67.712	Up-regulation
TKL_IRAK_IRAK1_ST	Q9HAT8	PELI2	P51617	IRAK1	S78	C73R	73	Missense	distal	-5	no	72.191	70.103	EPSD	TCGA;ICGC;COSMIC	67.712	Down-regulation
TKL_IRAK_IRAK1_ST	Q9HAT8	PELI2	P51617	IRAK1	S78	I71S	71	Missense	distal	-7	no	72.191	68.101	EPSD	TCGA;ICGC;COSMIC	67.712	Down-regulation
TKL_IRAK_IRAK1_ST	Q9HAT8	PELI2	P51617	IRAK1	S80	C73R	73	Missense	distal	-7	no	91.169	90.670	EPSD	TCGA;ICGC;COSMIC	67.712	Down-regulation
TKL_IRAK_IRAK1_ST	Q9HAT8	PELI2	P51617	IRAK1	T82	V89M	89	Missense	distal	7	no	113.740	100.504	EPSD	TCGA;ICGC;COSMIC	67.712	Down-regulation
TKL_IRAK_IRAK1_ST	Q9HAT8	PELI2	P51617	IRAK1	S84	V91M	91	Missense	distal	7	no	75.820	62.585	EPSD	TCGA;ICGC;COSMIC	67.712	Loss
TKL_IRAK_IRAK1_ST	Q9HAT8	PELI2	P51617	IRAK1	S84	V89M	89	Missense	distal	5	no	75.820	77.716	EPSD	TCGA;ICGC;COSMIC	67.712	Up-regulation
TKL_IRAK_IRAK1_ST	Q9HAT8	PELI2	P51617	IRAK1	T88	E92G	92	Missense	distal	4	no	85.663	83.537	EPSD	TCGA;ICGC;COSMIC	67.712	Down-regulation
TKL_IRAK_IRAK1_ST	Q9HAT8	PELI2	P51617	IRAK1	T88	V91M	91	Missense	distal	3	no	85.663	82.669	EPSD	TCGA;ICGC;COSMIC	67.712	Down-regulation
TKL_IRAK_IRAK1_ST	Q9HAT8	PELI2	P51617	IRAK1	T88	V89M	89	Missense	proximal	1	no	85.663	87.228	EPSD	TCGA;ICGC;COSMIC	67.712	Up-regulation
TKL_IRAK_IRAK1_ST	Q9HAT8	PELI2	P51617	IRAK1	S235	R229Q	229	Missense	distal	-6	no	78.469	88.579	EPSD	TCGA;ICGC;COSMIC	67.712	Up-regulation
TKL_IRAK_IRAK1_ST	Q9HAT8	PELI2	P51617	IRAK1	S235	Q228P	228	Missense	distal	-7	no	78.469	73.746	EPSD	TCGA;ICGC;COSMIC	67.712	Down-regulation
TKL_IRAK_IRAK1_ST	Q9HAT8	PELI2	P51617	IRAK1	T290	N297K	297	Missense	distal	7	no	135.720	143.708	PhosphoSitePlus	TCGA;ICGC;COSMIC	67.712	Up-regulation
TKL_IRAK_IRAK1_ST	Q9HAT8	PELI2	P51617	IRAK1	S295	N297K	297	Missense	proximal	2	no	95.219	101.533	EPSD	TCGA;ICGC;COSMIC	67.712	Up-regulation
TKL_IRAK_IRAK1_ST	P40763	STAT3	P51617	IRAK1	T545	S540L	540	Missense	distal	-5	no	71.747	78.710	EPSD	TCGA;ICGC;COSMIC	67.712	Up-regulation
TKL_IRAK_IRAK1_ST	P40763	STAT3	P51617	IRAK1	T632	S636F	636	Missense	distal	4	no	75.720	71.001	EPSD	TCGA;ICGC;COSMIC	67.712	Down-regulation
TKL_IRAK_IRAK1_ST	P40763	STAT3	P51617	IRAK1	T632	G630S	630	Missense	proximal	-2	no	75.720	75.951	EPSD	TCGA;ICGC;COSMIC	67.712	Up-regulation
TKL_IRAK_IRAK1_ST	P40763	STAT3	P51617	IRAK1	T632	P639L	639	Missense	distal	7	no	75.720	80.331	EPSD	TCGA;ICGC;COSMIC	67.712	Up-regulation
TKL_IRAK_IRAK1_ST	P40763	STAT3	P51617	IRAK1	T632	E638K	638	Missense	distal	6	no	75.720	78.688	EPSD	TCGA;ICGC;COSMIC	67.712	Up-regulation
TKL_IRAK_IRAK1_ST	P40763	STAT3	P51617	IRAK1	T632	T632I	632	Missense	central	0	yes	75.720	0.000	EPSD	TCGA;ICGC;COSMIC	67.712	Loss
TKL_IRAK_IRAK1_ST	P40763	STAT3	P51617	IRAK1	T632	V637M	637	Missense	distal	5	no	75.720	77.616	EPSD	TCGA;ICGC;COSMIC	67.712	Up-regulation
TKL_IRAK_IRAK1_ST	P40763	STAT3	P51617	IRAK1	S727	R729H	729	Missense	proximal	2	no	112.460	112.743	PhosphoSitePlus	TCGA;ICGC;COSMIC;GDSC;CCLE	67.712	Up-regulation
TKL_IRAK_IRAK1_ST	P40763	STAT3	P51617	IRAK1	S727	P725L	725	Missense	proximal	-2	no	112.460	111.923	PhosphoSitePlus	TCGA;ICGC;COSMIC	67.712	Down-regulation
CMGC_CDKL_CDKL5_ST	Q9HCJ2	LRRC4C	O76039	CDKL5	S173	S173Y	173	Missense	central	0	yes	4.176	0.000	EPSD	TCGA;COSMIC	2.968	Loss
CMGC_CDKL_CDKL5_ST	Q9HCJ2	LRRC4C	O76039	CDKL5	S173	G180V	180	Missense	distal	7	no	4.176	4.160	EPSD	TCGA;ICGC;COSMIC	2.968	Down-regulation
CMGC_CDKL_CDKL5_ST	Q9HCJ2	LRRC4C	O76039	CDKL5	S173	P172S	172	Missense	proximal	-1	no	4.176	3.977	EPSD	TCGA;ICGC;COSMIC	2.968	Down-regulation
CMGC_CDKL_CDKL5_ST	Q9HCJ2	LRRC4C	O76039	CDKL5	S173	P172A	172	Missense	proximal	-1	no	4.176	3.987	EPSD	TCGA;ICGC;COSMIC	2.968	Down-regulation
CMGC_CDKL_CDKL5_ST	Q9HCJ2	LRRC4C	O76039	CDKL5	S173	L174S	174	Missense	proximal	1	no	4.176	4.305	EPSD	TCGA;ICGC;COSMIC	2.968	Up-regulation
CMGC_CDKL_CDKL5_ST	Q9HCJ2	LRRC4C	O76039	CDKL5	S173	R175L	175	Missense	proximal	2	no	4.176	4.175	EPSD	TCGA;ICGC;COSMIC;GDSC;CCLE	2.968	Down-regulation
CMGC_CDKL_CDKL5_ST	Q9HCJ2	LRRC4C	O76039	CDKL5	S173	R175H	175	Missense	proximal	2	no	4.176	4.156	EPSD	TCGA;ICGC;COSMIC	2.968	Down-regulation
CMGC_CDKL_CDKL5_ST	Q9HCJ2	LRRC4C	O76039	CDKL5	S173	A167V	167	Missense	distal	-6	no	4.176	4.124	EPSD	TCGA;ICGC;COSMIC	2.968	Down-regulation
CMGC_CDKL_CDKL5_ST	Q9HCJ2	LRRC4C	O76039	CDKL5	S173	P172L	172	Missense	proximal	-1	no	4.176	4.059	EPSD	TCGA;ICGC;COSMIC	2.968	Down-regulation
CMGC_CDKL_CDKL5_ST	Q9HCJ2	LRRC4C	O76039	CDKL5	S173	Y166C	166	Missense	distal	-7	no	4.176	4.585	EPSD	TCGA;ICGC;COSMIC	2.968	Up-regulation
CMGC_CDKL_CDKL5_ST	Q9HCJ2	LRRC4C	O76039	CDKL5	S173	R170K	170	Missense	distal	-3	no	4.176	3.906	EPSD	TCGA;ICGC;COSMIC	2.968	Down-regulation
CMGC_CDKL_CDKL5_ST	Q9HCJ2	LRRC4C	O76039	CDKL5	S383	R376W	376	Missense	distal	-7	no	2.790	3.079	EPSD	TCGA;ICGC;COSMIC	2.968	Gain
CMGC_CDKL_CDKL5_ST	Q9HCJ2	LRRC4C	O76039	CDKL5	S631	Q636H	636	Missense	distal	5	no	6.210	6.213	PhosphoSitePlus	TCGA;ICGC;COSMIC	2.968	Up-regulation
CMGC_CDKL_CDKL5_ST	Q9HCJ2	LRRC4C	O76039	CDKL5	S631	D633E	633	Missense	proximal	2	no	6.210	6.002	PhosphoSitePlus	TCGA;ICGC;COSMIC	2.968	Down-regulation
CMGC_CDKL_CDKL5_ST	Q9HCJ2	LRRC4C	O76039	CDKL5	S631	E637Q	637	Missense	distal	6	no	6.210	5.958	PhosphoSitePlus	TCGA;ICGC;COSMIC	2.968	Down-regulation
CMGC_CDKL_CDKL5_ST	Q9HCJ2	LRRC4C	O76039	CDKL5	S631	M629I	629	Missense	proximal	-2	no	6.210	6.115	PhosphoSitePlus	TCGA;ICGC;COSMIC;GDSC;CCLE	2.968	Down-regulation
CMGC_CDKL_CDKL5_ST	Q9HCJ2	LRRC4C	O76039	CDKL5	S631	K632I	632	Missense	proximal	1	no	6.210	6.162	PhosphoSitePlus	TCGA;ICGC	2.968	Down-regulation
CMGC_CDKL_CDKL5_ST	Q9HCJ2	LRRC4C	O76039	CDKL5	S631	R628Q	628	Missense	distal	-3	no	6.210	5.681	PhosphoSitePlus	TCGA;ICGC;COSMIC;GDSC;CCLE	2.968	Down-regulation
CMGC_CDKL_CDKL5_ST	Q9HCJ2	LRRC4C	O76039	CDKL5	S631	P624L	624	Missense	distal	-7	no	6.210	4.040	PhosphoSitePlus	TCGA;ICGC;COSMIC	2.968	Down-regulation
CMGC_CDKL_CDKL5_ST	O76039	CDKL5	O76039	CDKL5	T169	V172I	172	Missense	distal	3	no	12.683	12.374	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	2.968	Down-regulation
CMGC_CDKL_CDKL5_ST	O76039	CDKL5	O76039	CDKL5	T169	R175I	175	Missense	distal	6	no	12.683	12.211	EPSD;PhosphoSitePlus	TCGA;ICGC	2.968	Down-regulation
CMGC_CDKL_CDKL5_ST	O76039	CDKL5	O76039	CDKL5	S343	I346V	346	Missense	distal	3	no	2.741	3.049	EPSD	TCGA;ICGC;COSMIC	2.968	Gain
CMGC_CDKL_CDKL5_ST	O76039	CDKL5	O76039	CDKL5	S350	I346V	346	Missense	distal	-4	no	4.962	4.947	EPSD	TCGA;ICGC;COSMIC	2.968	Down-regulation
CMGC_CDKL_CDKL5_ST	O76039	CDKL5	O76039	CDKL5	S350	R355W	355	Missense	distal	5	no	4.962	4.966	EPSD	TCGA;ICGC;COSMIC	2.968	Up-regulation
CMGC_CDKL_CDKL5_ST	O76039	CDKL5	O76039	CDKL5	S350	L353M	353	Missense	distal	3	no	4.962	5.008	EPSD	TCGA;ICGC;COSMIC	2.968	Up-regulation
CMGC_CDKL_CDKL5_ST	O76039	CDKL5	O76039	CDKL5	S375	G373V	373	Missense	proximal	-2	no	2.764	3.108	EPSD	TCGA;ICGC;COSMIC	2.968	Gain
CMGC_CDKL_CDKL5_ST	O76039	CDKL5	O76039	CDKL5	S526	P530A	530	Missense	distal	4	no	2.979	3.042	EPSD	TCGA;ICGC;COSMIC	2.968	Up-regulation
CMGC_CDKL_CDKL5_ST	O76039	CDKL5	O76039	CDKL5	S766	K772N	772	Missense	distal	6	no	4.173	3.995	EPSD	TCGA;ICGC	2.968	Down-regulation
CMGC_CDKL_CDKL5_ST	O76039	CDKL5	O76039	CDKL5	S766	L771F	771	Missense	distal	5	no	4.173	4.176	EPSD	TCGA;ICGC;COSMIC	2.968	Up-regulation
CMGC_CDKL_CDKL5_ST	O76039	CDKL5	O76039	CDKL5	S768	K772N	772	Missense	distal	4	no	2.983	2.955	EPSD	TCGA;ICGC	2.968	Loss
CMGC_CDKL_CDKL5_ST	O76039	CDKL5	O76039	CDKL5	S768	L771F	771	Missense	distal	3	no	2.983	2.940	EPSD	TCGA;ICGC;COSMIC	2.968	Loss
CMGC_CDKL_CDKL5_ST	O76039	CDKL5	O76039	CDKL5	S796	T803K	803	Missense	distal	7	no	3.186	3.199	EPSD	TCGA;ICGC;COSMIC	2.968	Up-regulation
CMGC_CDKL_CDKL5_ST	O76039	CDKL5	O76039	CDKL5	S796	T792A	792	Missense	distal	-4	no	3.186	3.181	EPSD	TCGA;ICGC;COSMIC	2.968	Down-regulation
CMGC_CDKL_CDKL5_ST	O76039	CDKL5	O76039	CDKL5	S796	T803M	803	Missense	distal	7	no	3.186	3.180	EPSD	TCGA;ICGC	2.968	Down-regulation
CMGC_CDKL_CDKL5_ST	O76039	CDKL5	O76039	CDKL5	S796	S790F	790	Missense	distal	-6	no	3.186	3.151	EPSD	TCGA;ICGC;COSMIC	2.968	Down-regulation
CMGC_CDKL_CDKL5_ST	O76039	CDKL5	O76039	CDKL5	T803	T803K	803	Missense	central	0	yes	2.974	0.000	EPSD	TCGA;ICGC;COSMIC	2.968	Loss
CMGC_CDKL_CDKL5_ST	O76039	CDKL5	O76039	CDKL5	T803	T803M	803	Missense	central	0	yes	2.974	0.000	EPSD	TCGA;ICGC	2.968	Loss
CMGC_CDKL_CDKL5_ST	O76039	CDKL5	O76039	CDKL5	T803	K806T	806	Missense	distal	3	no	2.974	2.813	EPSD	TCGA;ICGC	2.968	Loss
CMGC_CDKL_CDKL5_ST	Q66K74	MAP1S	O76039	CDKL5	S321	E314K	314	Missense	distal	-7	no	4.124	4.198	EPSD	TCGA;COSMIC	2.968	Up-regulation
CMGC_CDKL_CDKL5_ST	Q66K74	MAP1S	O76039	CDKL5	S481	V476M	476	Missense	distal	-5	no	5.895	5.849	EPSD	TCGA;COSMIC	2.968	Down-regulation
CMGC_CDKL_CDKL5_ST	Q66K74	MAP1S	O76039	CDKL5	S766	R773Q	773	Missense	distal	7	no	5.382	5.364	EPSD	TCGA;COSMIC	2.968	Down-regulation
CMGC_CDKL_CDKL5_ST	Q66K74	MAP1S	O76039	CDKL5	S766	S762I	762	Missense	distal	-4	no	5.382	5.383	EPSD	TCGA;COSMIC	2.968	Up-regulation
CMGC_CDKL_CDKL5_ST	Q66K74	MAP1S	O76039	CDKL5	S788	T782M	782	Missense	distal	-6	no	3.706	3.663	EPSD	TCGA;COSMIC	2.968	Down-regulation
CMGC_CDKL_CDKL5_ST	Q66K74	MAP1S	O76039	CDKL5	S788	S788N	788	Missense	central	0	yes	3.706	0.000	EPSD	TCGA;COSMIC	2.968	Loss
CMGC_CDKL_CDKL5_ST	Q66K74	MAP1S	O76039	CDKL5	S788	P792S	792	Missense	distal	4	no	3.706	3.750	EPSD	TCGA;COSMIC	2.968	Up-regulation
CMGC_CDKL_CDKL5_ST	Q66K74	MAP1S	O76039	CDKL5	S790	S788N	788	Missense	proximal	-2	no	2.214	3.089	EPSD	TCGA;COSMIC	2.968	Gain
CMGC_CDKL_CDKL5_ST	Q66K74	MAP1S	O76039	CDKL5	T925	G930E	930	Missense	distal	5	no	5.304	5.300	EPSD	TCGA	2.968	Down-regulation
CMGC_CDKL_CDKL5_ST	Q66K74	MAP1S	O76039	CDKL5	T925	R926G	926	Missense	proximal	1	no	5.304	5.289	EPSD	TCGA;COSMIC	2.968	Down-regulation
CMGC_CDKL_CDKL5_ST	Q8TDM6	DLG5	O76039	CDKL5	S711	R707Q	707	Missense	distal	-4	no	3.698	3.701	EPSD	TCGA;ICGC;COSMIC	2.968	Up-regulation
CMGC_CDKL_CDKL5_ST	Q8TDM6	DLG5	O76039	CDKL5	S711	R707W	707	Missense	distal	-4	no	3.698	3.699	EPSD	TCGA;ICGC;COSMIC	2.968	Up-regulation
CMGC_CDKL_CDKL5_ST	Q8TDM6	DLG5	O76039	CDKL5	S711	S711F	711	Missense	central	0	yes	3.698	0.000	EPSD	TCGA;ICGC;COSMIC	2.968	Loss
CMGC_CDKL_CDKL5_ST	Q8TDM6	DLG5	O76039	CDKL5	T849	Q843H	843	Missense	distal	-6	no	4.364	4.507	EPSD	TCGA;ICGC;COSMIC	2.968	Up-regulation
CMGC_CDKL_CDKL5_ST	Q8TDM6	DLG5	O76039	CDKL5	S865	G862E	862	Missense	distal	-3	no	4.577	4.817	EPSD	TCGA;ICGC;COSMIC	2.968	Up-regulation
CMGC_CDKL_CDKL5_ST	Q8TDM6	DLG5	O76039	CDKL5	S865	P858Q	858	Missense	distal	-7	no	4.577	3.339	EPSD	TCGA;ICGC;COSMIC	2.968	Down-regulation
CMGC_CDKL_CDKL5_ST	Q8TDM6	DLG5	O76039	CDKL5	T984	N977S	977	Missense	distal	-7	no	1.965	3.118	EPSD	TCGA;ICGC;COSMIC	2.968	Gain
CMGC_CDKL_CDKL5_ST	Q8TDM6	DLG5	O76039	CDKL5	S1118	P1125A	1125	Missense	distal	7	no	4.571	4.600	EPSD	TCGA;ICGC;COSMIC	2.968	Up-regulation
CMGC_CDKL_CDKL5_ST	Q8TDM6	DLG5	O76039	CDKL5	S1118	R1112L	1112	Missense	distal	-6	no	4.571	4.642	EPSD	TCGA	2.968	Up-regulation
CMGC_CDKL_CDKL5_ST	Q8TDM6	DLG5	O76039	CDKL5	S1118	R1120W	1120	Missense	proximal	2	no	4.571	4.553	EPSD	TCGA;ICGC;COSMIC	2.968	Down-regulation
CMGC_CDKL_CDKL5_ST	Q8TDM6	DLG5	O76039	CDKL5	S1265	R1260G	1260	Missense	distal	-5	no	4.843	4.532	EPSD	TCGA;ICGC;COSMIC	2.968	Down-regulation
CMGC_CDKL_CDKL5_ST	Q8TDM6	DLG5	O76039	CDKL5	S1265	E1272K	1272	Missense	distal	7	no	4.843	4.870	EPSD	TCGA;ICGC;COSMIC	2.968	Up-regulation
CMGC_CDKL_CDKL5_ST	Q8TDM6	DLG5	O76039	CDKL5	S1265	A1271V	1271	Missense	distal	6	no	4.843	4.494	EPSD	TCGA;ICGC;COSMIC	2.968	Down-regulation
CMGC_CDKL_CDKL5_ST	Q8TDM6	DLG5	O76039	CDKL5	S1265	R1260H	1260	Missense	distal	-5	no	4.843	4.325	EPSD	TCGA;COSMIC	2.968	Down-regulation
CMGC_CDKL_CDKL5_ST	Q8TDM6	DLG5	O76039	CDKL5	S1278	P1283L	1283	Missense	distal	5	no	4.516	4.507	EPSD	TCGA;COSMIC	2.968	Down-regulation
CMGC_CDKL_CDKL5_ST	Q8TDM6	DLG5	O76039	CDKL5	S1278	E1272K	1272	Missense	distal	-6	no	4.516	4.529	EPSD	TCGA;ICGC;COSMIC	2.968	Up-regulation
CMGC_CDKL_CDKL5_ST	Q8TDM6	DLG5	O76039	CDKL5	S1278	A1271V	1271	Missense	distal	-7	no	4.516	4.182	EPSD	TCGA;ICGC;COSMIC	2.968	Down-regulation
CMGC_CDKL_CDKL5_ST	Q8TDM6	DLG5	O76039	CDKL5	S1278	K1275N	1275	Missense	distal	-3	no	4.516	4.282	EPSD	TCGA;COSMIC	2.968	Down-regulation
CMGC_CDKL_CDKL5_ST	Q8TDM6	DLG5	O76039	CDKL5	S1314	L1307M	1307	Missense	distal	-7	no	2.607	3.181	EPSD	TCGA;ICGC	2.968	Gain
CMGC_CDKL_CDKL5_ST	Q8TDM6	DLG5	O76039	CDKL5	S1700	S1700Y	1700	Missense	central	0	yes	4.675	0.000	EPSD	TCGA;ICGC;COSMIC	2.968	Loss
CMGC_CDKL_CDKL5_ST	Q8TDM6	DLG5	O76039	CDKL5	S1700	S1700F	1700	Missense	central	0	yes	4.675	0.000	EPSD	TCGA;ICGC;COSMIC	2.968	Loss
CMGC_MAPK_p38_MAPK11_ST	P15336	ATF2	Q15759	MAPK11	T69	P70S	70	Missense	proximal	1	no	47.733	32.234	PhosphoSitePlus;EPSD	TCGA;COSMIC	33.886	Loss
CMGC_MAPK_p38_MAPK11_ST	P15336	ATF2	Q15759	MAPK11	T71	P70S	70	Missense	proximal	-1	no	48.904	48.849	EPSD;PhosphoSitePlus	TCGA;COSMIC	33.886	Down-regulation
CMGC_MAPK_p38_MAPK11_ST	P15336	ATF2	Q15759	MAPK11	S90	E93Q	93	Missense	distal	3	no	41.360	40.875	EPSD	TCGA;COSMIC	33.886	Down-regulation
CMGC_MAPK_p38_MAPK11_ST	P15336	ATF2	Q15759	MAPK11	S90	G83D	83	Missense	distal	-7	no	41.360	41.383	EPSD	TCGA;COSMIC	33.886	Up-regulation
CMGC_MAPK_p38_MAPK11_ST	P15336	ATF2	Q15759	MAPK11	S112	T116A	116	Missense	distal	4	no	44.471	44.440	EPSD	TCGA;COSMIC	33.886	Down-regulation
CMGC_MAPK_p38_MAPK11_ST	P15336	ATF2	Q15759	MAPK11	S112	S112P	112	Missense	central	0	yes	44.471	0.000	EPSD	TCGA;COSMIC	33.886	Loss
CMGC_MAPK_p38_MAPK11_ST	P15336	ATF2	Q15759	MAPK11	T116	T116A	116	Missense	central	0	yes	41.067	0.000	EPSD	TCGA;COSMIC	33.886	Loss
CMGC_MAPK_p38_MAPK11_ST	P15336	ATF2	Q15759	MAPK11	T116	S112P	112	Missense	distal	-4	no	41.067	39.350	EPSD	TCGA;COSMIC	33.886	Down-regulation
CMGC_MAPK_p38_MAPK11_ST	P15336	ATF2	Q15759	MAPK11	S136	D135N	135	Missense	proximal	-1	no	36.910	36.819	EPSD	TCGA	33.886	Down-regulation
CMGC_MAPK_p38_MAPK11_ST	P15336	ATF2	Q15759	MAPK11	S136	S136N	136	Missense	central	0	yes	36.910	0.000	EPSD	TCGA	33.886	Loss
CMGC_MAPK_p38_MAPK11_ST	P15336	ATF2	Q15759	MAPK11	S266	G263C	263	Missense	distal	-3	no	33.396	34.611	EPSD	TCGA;COSMIC	33.886	Gain
CMGC_MAPK_p38_MAPK11_ST	P15336	ATF2	Q15759	MAPK11	S314	P312L	312	Missense	proximal	-2	no	35.026	34.690	EPSD	TCGA;COSMIC	33.886	Down-regulation
CMGC_MAPK_p38_MAPK11_ST	P15336	ATF2	Q15759	MAPK11	S314	S321F	321	Missense	distal	7	no	35.026	34.007	EPSD	TCGA;COSMIC	33.886	Down-regulation
CMGC_MAPK_p38_MAPK11_ST	P15336	ATF2	Q15759	MAPK11	S314	E308Q	308	Missense	distal	-6	no	35.026	34.979	EPSD	TCGA;COSMIC	33.886	Down-regulation
CMGC_MAPK_p38_MAPK11_ST	P15336	ATF2	Q15759	MAPK11	S314	S310F	310	Missense	distal	-4	no	35.026	32.535	EPSD	TCGA;COSMIC	33.886	Loss
CMGC_MAPK_p38_MAPK11_ST	P15336	ATF2	Q15759	MAPK11	T325	P326S	326	Missense	proximal	1	no	40.490	24.992	EPSD	TCGA;COSMIC	33.886	Loss
CMGC_MAPK_p38_MAPK11_ST	P15336	ATF2	Q15759	MAPK11	T325	S321F	321	Missense	distal	-4	no	40.490	37.999	EPSD	TCGA;COSMIC	33.886	Down-regulation
CMGC_MAPK_p38_MAPK11_ST	P15336	ATF2	Q15759	MAPK11	S328	P326S	326	Missense	proximal	-2	no	36.572	36.510	EPSD	TCGA;COSMIC	33.886	Down-regulation
CMGC_MAPK_p38_MAPK11_ST	P15336	ATF2	Q15759	MAPK11	S328	P334A	334	Missense	distal	6	no	36.572	36.584	EPSD	TCGA;COSMIC	33.886	Up-regulation
CMGC_MAPK_p38_MAPK11_ST	P15336	ATF2	Q15759	MAPK11	S328	S321F	321	Missense	distal	-7	no	36.572	36.324	EPSD	TCGA;COSMIC	33.886	Down-regulation
CMGC_MAPK_p38_MAPK11_ST	P15336	ATF2	Q15759	MAPK11	T333	P326S	326	Missense	distal	-7	no	42.604	42.743	EPSD	TCGA;COSMIC	33.886	Up-regulation
CMGC_MAPK_p38_MAPK11_ST	P15336	ATF2	Q15759	MAPK11	T333	P334A	334	Missense	proximal	1	no	42.604	33.569	EPSD	TCGA;COSMIC	33.886	Loss
CMGC_MAPK_p38_MAPK11_ST	P15336	ATF2	Q15759	MAPK11	T333	T339A	339	Missense	distal	6	no	42.604	42.637	EPSD	TCGA;COSMIC	33.886	Up-regulation
CMGC_MAPK_p38_MAPK11_ST	P15336	ATF2	Q15759	MAPK11	S446	Q453H	453	Missense	distal	7	no	43.614	43.730	EPSD	TCGA;COSMIC	33.886	Up-regulation
CMGC_MAPK_p38_MAPK11_ST	P15336	ATF2	Q15759	MAPK11	S455	S456L	456	Missense	proximal	1	no	29.393	35.074	EPSD	TCGA;COSMIC	33.886	Gain
CMGC_MAPK_p38_MAPK11_ST	P15336	ATF2	Q15759	MAPK11	S464	A471V	471	Missense	distal	7	no	41.606	41.215	EPSD	TCGA;COSMIC	33.886	Down-regulation
CMGC_MAPK_p38_MAPK11_ST	P04179	SOD2	Q15759	MAPK11	T79	L84V	84	Missense	distal	5	no	45.525	45.911	PhosphoSitePlus;EPSD	TCGA;COSMIC	33.886	Up-regulation
CMGC_MAPK_p38_MAPK11_ST	P04179	SOD2	Q15759	MAPK11	T79	D77N	77	Missense	proximal	-2	no	45.525	45.560	PhosphoSitePlus;EPSD	TCGA;COSMIC	33.886	Up-regulation
CMGC_MAPK_p38_MAPK11_ST	P04179	SOD2	Q15759	MAPK11	T79	K75T	75	Missense	distal	-4	no	45.525	45.075	PhosphoSitePlus;EPSD	TCGA;ICGC	33.886	Down-regulation
CMGC_MAPK_p38_MAPK11_ST	P04179	SOD2	Q15759	MAPK11	S106	G110D	110	Missense	distal	4	no	47.202	46.723	EPSD;PhosphoSitePlus	TCGA;COSMIC	33.886	Down-regulation
CMGC_MAPK_p38_MAPK11_ST	Q15759	MAPK11	Q15759	MAPK11	T241	G240D	240	Missense	proximal	-1	no	46.807	46.737	PhosphoSitePlus;EPSD	TCGA;ICGC	33.886	Down-regulation
CMGC_MAPK_p38_MAPK11_ST	Q15759	MAPK11	Q15759	MAPK11	T241	R234C	234	Missense	distal	-7	no	46.807	46.610	PhosphoSitePlus;EPSD	TCGA;ICGC;COSMIC	33.886	Down-regulation
CMGC_MAPK_p38_MAPK11_ST	Q15759	MAPK11	Q15759	MAPK11	T241	R234H	234	Missense	distal	-7	no	46.807	46.698	PhosphoSitePlus;EPSD	TCGA;ICGC;COSMIC	33.886	Down-regulation
CMGC_MAPK_p38_MAPK11_ST	Q15759	MAPK11	Q15759	MAPK11	S243	G240D	240	Missense	distal	-3	no	35.783	36.170	EPSD	TCGA;ICGC	33.886	Up-regulation
CMGC_MAPK_p38_MAPK11_ST	O00418	EEF2K	Q15759	MAPK11	S74	E67K	67	Missense	distal	-7	no	41.457	41.544	EPSD	TCGA;ICGC;COSMIC	33.886	Up-regulation
CMGC_MAPK_p38_MAPK11_ST	O00418	EEF2K	Q15759	MAPK11	S74	H80Y	80	Missense	distal	6	no	41.457	41.423	EPSD	TCGA;ICGC;COSMIC	33.886	Down-regulation
CMGC_MAPK_p38_MAPK11_ST	O00418	EEF2K	Q15759	MAPK11	S74	R68W	68	Missense	distal	-6	no	41.457	41.360	EPSD	TCGA	33.886	Down-regulation
CMGC_MAPK_p38_MAPK11_ST	O00418	EEF2K	Q15759	MAPK11	S74	S74C	74	Missense	central	0	yes	41.457	0.000	EPSD	TCGA;ICGC;COSMIC	33.886	Loss
CMGC_MAPK_p38_MAPK11_ST	O00418	EEF2K	Q15759	MAPK11	S359	S366F	366	Missense	distal	7	no	45.186	44.167	EPSD	TCGA;ICGC;COSMIC	33.886	Down-regulation
CMGC_MAPK_p38_MAPK11_ST	O00418	EEF2K	Q15759	MAPK11	S359	S366C	366	Missense	distal	7	no	45.186	43.586	EPSD	TCGA;ICGC;COSMIC	33.886	Down-regulation
CMGC_MAPK_p38_MAPK11_ST	O00418	EEF2K	Q15759	MAPK11	S396	A400V	400	Missense	distal	4	no	51.873	49.859	PhosphoSitePlus	TCGA;ICGC;COSMIC	33.886	Down-regulation
CMGC_MAPK_p38_MAPK11_ST	O00418	EEF2K	Q15759	MAPK11	S396	S396F	396	Missense	central	0	yes	51.873	0.000	PhosphoSitePlus	TCGA;ICGC;COSMIC	33.886	Loss
CMGC_MAPK_p38_MAPK11_ST	O00418	EEF2K	Q15759	MAPK11	S396	S392F	392	Missense	distal	-4	no	51.873	49.382	PhosphoSitePlus	TCGA;ICGC;COSMIC	33.886	Down-regulation
CMGC_MAPK_p38_MAPK11_ST	O00418	EEF2K	Q15759	MAPK11	S396	D391N	391	Missense	distal	-5	no	51.873	51.770	PhosphoSitePlus	TCGA;ICGC	33.886	Down-regulation
CMGC_MAPK_p38_MAPK11_ST	O00418	EEF2K	Q15759	MAPK11	T401	A400V	400	Missense	proximal	-1	no	39.858	39.116	EPSD	TCGA;ICGC;COSMIC	33.886	Down-regulation
CMGC_MAPK_p38_MAPK11_ST	O00418	EEF2K	Q15759	MAPK11	T401	S396F	396	Missense	distal	-5	no	39.858	39.566	EPSD	TCGA;ICGC;COSMIC	33.886	Down-regulation
CMGC_MAPK_p38_MAPK11_ST	Q00613	HSF1	Q15759	MAPK11	S275	P276L	276	Missense	proximal	1	no	42.662	32.845	EPSD	TCGA;COSMIC	33.886	Loss
CMGC_MAPK_p38_MAPK11_ST	Q00613	HSF1	Q15759	MAPK11	S275	M277V	277	Missense	proximal	2	no	42.662	42.588	EPSD	TCGA;COSMIC	33.886	Down-regulation
CMGC_MAPK_p38_MAPK11_ST	Q00613	HSF1	Q15759	MAPK11	S279	P276L	276	Missense	distal	-3	no	40.834	41.252	EPSD	TCGA;COSMIC	33.886	Up-regulation
CMGC_MAPK_p38_MAPK11_ST	Q00613	HSF1	Q15759	MAPK11	S279	E286K	286	Missense	distal	7	no	40.834	40.868	EPSD	TCGA;COSMIC	33.886	Up-regulation
CMGC_MAPK_p38_MAPK11_ST	Q00613	HSF1	Q15759	MAPK11	S279	M277V	277	Missense	proximal	-2	no	40.834	40.913	EPSD	TCGA;COSMIC	33.886	Up-regulation
CMGC_MAPK_p38_MAPK11_ST	Q00613	HSF1	Q15759	MAPK11	S292	R296C	296	Missense	distal	4	no	44.972	43.407	EPSD	TCGA;COSMIC	33.886	Down-regulation
CMGC_MAPK_p38_MAPK11_ST	Q00613	HSF1	Q15759	MAPK11	S292	P288L	288	Missense	distal	-4	no	44.972	43.400	EPSD	TCGA;COSMIC	33.886	Down-regulation
CMGC_MAPK_p38_MAPK11_ST	Q00613	HSF1	Q15759	MAPK11	S292	E286K	286	Missense	distal	-6	no	44.972	45.012	EPSD	TCGA;COSMIC	33.886	Up-regulation
CMGC_MAPK_p38_MAPK11_ST	Q00613	HSF1	Q15759	MAPK11	S303	E300Q	300	Missense	distal	-3	no	47.052	47.319	EPSD;PhosphoSitePlus	TCGA	33.886	Up-regulation
CMGC_MAPK_p38_MAPK11_ST	Q00613	HSF1	Q15759	MAPK11	S303	R296C	296	Missense	distal	-7	no	47.052	46.855	EPSD;PhosphoSitePlus	TCGA;COSMIC	33.886	Down-regulation
CMGC_MAPK_p38_MAPK11_ST	Q00613	HSF1	Q15759	MAPK11	S307	E300Q	300	Missense	distal	-7	no	47.026	46.921	PhosphoSitePlus;EPSD	TCGA	33.886	Down-regulation
CMGC_MAPK_p38_MAPK11_ST	Q00613	HSF1	Q15759	MAPK11	S314	R317H	317	Missense	distal	3	no	37.205	37.030	EPSD	TCGA;COSMIC	33.886	Down-regulation
CMGC_MAPK_p38_MAPK11_ST	Q00613	HSF1	Q15759	MAPK11	S314	S320F	320	Missense	distal	6	no	37.205	37.280	EPSD	TCGA;COSMIC	33.886	Up-regulation
CMGC_MAPK_p38_MAPK11_ST	Q00613	HSF1	Q15759	MAPK11	T323	R317H	317	Missense	distal	-6	no	34.256	34.182	EPSD	TCGA;COSMIC	33.886	Down-regulation
CMGC_MAPK_p38_MAPK11_ST	Q00613	HSF1	Q15759	MAPK11	T323	T323I	323	Missense	central	0	yes	34.256	0.000	EPSD	TCGA;COSMIC	33.886	Loss
CMGC_MAPK_p38_MAPK11_ST	Q00613	HSF1	Q15759	MAPK11	T323	S320F	320	Missense	distal	-3	no	34.256	35.076	EPSD	TCGA;COSMIC	33.886	Up-regulation
CMGC_MAPK_p38_MAPK11_ST	Q00613	HSF1	Q15759	MAPK11	T323	A329T	329	Missense	distal	6	no	34.256	34.223	EPSD	TCGA;COSMIC	33.886	Down-regulation
CMGC_MAPK_p38_MAPK11_ST	Q00613	HSF1	Q15759	MAPK11	T323	P327L	327	Missense	distal	4	no	34.256	33.033	EPSD	TCGA	33.886	Loss
CMGC_MAPK_p38_MAPK11_ST	Q00613	HSF1	Q15759	MAPK11	S326	D332Y	332	Missense	distal	6	no	48.115	48.096	EPSD;PhosphoSitePlus	TCGA;COSMIC	33.886	Down-regulation
CMGC_MAPK_p38_MAPK11_ST	Q00613	HSF1	Q15759	MAPK11	S326	T323I	323	Missense	distal	-3	no	48.115	49.220	EPSD;PhosphoSitePlus	TCGA;COSMIC	33.886	Up-regulation
CMGC_MAPK_p38_MAPK11_ST	Q00613	HSF1	Q15759	MAPK11	S326	S320F	320	Missense	distal	-6	no	48.115	47.846	EPSD;PhosphoSitePlus	TCGA;COSMIC	33.886	Down-regulation
CMGC_MAPK_p38_MAPK11_ST	Q00613	HSF1	Q15759	MAPK11	S326	A329T	329	Missense	distal	3	no	48.115	48.873	EPSD;PhosphoSitePlus	TCGA;COSMIC	33.886	Up-regulation
CMGC_MAPK_p38_MAPK11_ST	Q00613	HSF1	Q15759	MAPK11	S326	S333F	333	Missense	distal	7	no	48.115	47.095	EPSD;PhosphoSitePlus	TCGA;COSMIC	33.886	Down-regulation
CMGC_MAPK_p38_MAPK11_ST	Q00613	HSF1	Q15759	MAPK11	S326	P327L	327	Missense	proximal	1	no	48.115	38.297	EPSD;PhosphoSitePlus	TCGA	33.886	Down-regulation
CMGC_MAPK_p38_MAPK11_ST	Q00613	HSF1	Q15759	MAPK11	T346	A351T	351	Missense	distal	5	no	35.196	35.587	EPSD	TCGA;COSMIC	33.886	Up-regulation
CMGC_MAPK_p38_MAPK11_ST	Q00613	HSF1	Q15759	MAPK11	T346	E339G	339	Missense	distal	-7	no	35.196	35.158	EPSD	TCGA;COSMIC	33.886	Down-regulation
CMGC_MAPK_p38_MAPK11_ST	Q00613	HSF1	Q15759	MAPK11	S363	P364S	364	Missense	proximal	1	no	44.089	28.590	EPSD	TCGA;COSMIC	33.886	Loss
CMGC_MAPK_p38_MAPK11_ST	Q00613	HSF1	Q15759	MAPK11	T369	P364S	364	Missense	distal	-5	no	45.588	45.747	EPSD	TCGA;COSMIC	33.886	Up-regulation
CMGC_MAPK_p38_MAPK11_ST	Q00613	HSF1	Q15759	MAPK11	S419	P420L	420	Missense	proximal	1	no	42.318	32.500	EPSD	TCGA;ICGC;COSMIC	33.886	Loss
CMGC_MAPK_p38_MAPK11_ST	Q00613	HSF1	Q15759	MAPK11	S419	P425S	425	Missense	distal	6	no	42.318	42.310	EPSD	TCGA;ICGC;COSMIC	33.886	Down-regulation
CMGC_MAPK_p38_MAPK11_ST	Q00613	HSF1	Q15759	MAPK11	S444	E441K	441	Missense	distal	-3	no	41.001	41.035	EPSD	TCGA;COSMIC	33.886	Up-regulation
CMGC_MAPK_p38_MAPK11_ST	Q00613	HSF1	Q15759	MAPK11	S458	E453K	453	Missense	distal	-5	no	42.074	42.090	EPSD	TCGA;COSMIC	33.886	Up-regulation
CMGC_MAPK_p38_MAPK11_ST	Q8N122	RPTOR	Q15759	MAPK11	S704	R709Q	709	Missense	distal	5	no	33.943	33.741	EPSD	TCGA;COSMIC	33.886	Loss
CMGC_MAPK_p38_MAPK11_ST	Q8N122	RPTOR	Q15759	MAPK11	T706	C713F	713	Missense	distal	7	no	35.602	36.183	EPSD	TCGA	33.886	Up-regulation
CMGC_MAPK_p38_MAPK11_ST	Q8N122	RPTOR	Q15759	MAPK11	T706	R709Q	709	Missense	distal	3	no	35.602	35.415	EPSD	TCGA;COSMIC	33.886	Down-regulation
CMGC_MAPK_p38_MAPK11_ST	Q8N122	RPTOR	Q15759	MAPK11	S711	C713F	713	Missense	proximal	2	no	44.879	44.549	EPSD	TCGA	33.886	Down-regulation
CMGC_MAPK_p38_MAPK11_ST	Q8N122	RPTOR	Q15759	MAPK11	S711	R709Q	709	Missense	proximal	-2	no	44.879	44.882	EPSD	TCGA;COSMIC	33.886	Up-regulation
CMGC_MAPK_p38_MAPK11_ST	Q8N122	RPTOR	Q15759	MAPK11	T714	S719F	719	Missense	distal	5	no	41.037	41.844	EPSD	TCGA;ICGC;COSMIC	33.886	Up-regulation
CMGC_MAPK_p38_MAPK11_ST	Q8N122	RPTOR	Q15759	MAPK11	T714	C713F	713	Missense	proximal	-1	no	41.037	41.025	EPSD	TCGA	33.886	Down-regulation
CMGC_MAPK_p38_MAPK11_ST	Q8N122	RPTOR	Q15759	MAPK11	T714	R709Q	709	Missense	distal	-5	no	41.037	40.994	EPSD	TCGA;COSMIC	33.886	Down-regulation
CMGC_MAPK_p38_MAPK11_ST	Q8N122	RPTOR	Q15759	MAPK11	T731	G724E	724	Missense	distal	-7	no	37.316	37.354	EPSD	TCGA;COSMIC	33.886	Up-regulation
CMGC_MAPK_p38_MAPK11_ST	Q8N122	RPTOR	Q15759	MAPK11	S771	E775K	775	Missense	distal	4	no	49.052	49.249	PhosphoSitePlus;EPSD	TCGA;COSMIC	33.886	Up-regulation
CMGC_MAPK_p38_MAPK11_ST	Q8N122	RPTOR	Q15759	MAPK11	S863	T857M	857	Missense	distal	-6	no	45.457	45.415	EPSD;PhosphoSitePlus	TCGA;COSMIC	33.886	Down-regulation
CMGC_MAPK_p38_MAPK11_ST	Q8N122	RPTOR	Q15759	MAPK11	S877	S877F	877	Missense	central	0	yes	36.051	0.000	EPSD	TCGA;COSMIC	33.886	Loss
CMGC_MAPK_p38_MAPK11_ST	Q8N122	RPTOR	Q15759	MAPK11	S877	P879L	879	Missense	proximal	2	no	36.051	36.314	EPSD	TCGA;COSMIC	33.886	Up-regulation
CMGC_MAPK_p38_MAPK11_ST	Q8N122	RPTOR	Q15759	MAPK11	S887	D891N	891	Missense	distal	4	no	42.638	42.109	EPSD	TCGA;COSMIC	33.886	Down-regulation
CMGC_MAPK_p38_MAPK11_ST	Q01094	E2F1	Q15759	MAPK11	S121	E124Q	124	Missense	distal	3	no	46.718	46.233	EPSD	TCGA;ICGC;COSMIC	33.886	Down-regulation
CMGC_MAPK_p38_MAPK11_ST	Q01094	E2F1	Q15759	MAPK11	S121	R127H	127	Missense	distal	6	no	46.718	46.721	EPSD	TCGA;ICGC;COSMIC;GDSC;CCLE	33.886	Up-regulation
CMGC_MAPK_p38_MAPK11_ST	Q01094	E2F1	Q15759	MAPK11	S131	E124Q	124	Missense	distal	-7	no	38.340	38.236	EPSD	TCGA;ICGC;COSMIC	33.886	Down-regulation
CMGC_MAPK_p38_MAPK11_ST	Q01094	E2F1	Q15759	MAPK11	S131	R127H	127	Missense	distal	-4	no	38.340	37.001	EPSD	TCGA;ICGC;COSMIC;GDSC;CCLE	33.886	Down-regulation
CMGC_MAPK_p38_MAPK11_ST	Q01094	E2F1	Q15759	MAPK11	S131	R138C	138	Missense	distal	7	no	38.340	37.364	EPSD	TCGA;ICGC;COSMIC;GDSC;CCLE	33.886	Down-regulation
CMGC_MAPK_p38_MAPK11_ST	Q01094	E2F1	Q15759	MAPK11	S307	I306V	306	Missense	proximal	-1	no	34.651	35.106	EPSD	TCGA;ICGC;COSMIC	33.886	Up-regulation
CMGC_MAPK_p38_MAPK11_ST	Q01094	E2F1	Q15759	MAPK11	T311	I306V	306	Missense	distal	-5	no	37.432	37.429	EPSD	TCGA;ICGC;COSMIC	33.886	Down-regulation
CMGC_MAPK_p38_MAPK11_ST	Q01094	E2F1	Q15759	MAPK11	S340	P346L	346	Missense	distal	6	no	35.695	35.732	EPSD	TCGA;ICGC;COSMIC	33.886	Up-regulation
CMGC_MAPK_p38_MAPK11_ST	Q01094	E2F1	Q15759	MAPK11	S341	P346L	346	Missense	distal	5	no	39.854	39.757	EPSD	TCGA;ICGC;COSMIC	33.886	Down-regulation
CMGC_MAPK_p38_MAPK11_ST	Q01094	E2F1	Q15759	MAPK11	S349	P346L	346	Missense	distal	-3	no	35.962	36.380	EPSD	TCGA;ICGC;COSMIC	33.886	Up-regulation
CMGC_MAPK_p38_MAPK11_ST	Q01094	E2F1	Q15759	MAPK11	S352	P346L	346	Missense	distal	-6	no	35.108	35.047	EPSD	TCGA;ICGC;COSMIC	33.886	Down-regulation
CMGC_MAPK_p38_MAPK11_ST	Q01094	E2F1	Q15759	MAPK11	S403	H406Y	406	Missense	distal	3	no	47.567	47.787	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	33.886	Up-regulation
CMGC_MAPK_p38_MAPK11_ST	Q01094	E2F1	Q15759	MAPK11	T433	D426N	426	Missense	distal	-7	no	44.423	44.411	PhosphoSitePlus;EPSD	TCGA;ICGC	33.886	Down-regulation
CMGC_MAPK_p38_MAPK11_ST	P00533	EGFR	Q15759	MAPK11	S227	R222C	222	Missense	distal	-5	no	34.848	34.599	EPSD	TCGA;COSMIC	33.886	Down-regulation
CMGC_MAPK_p38_MAPK11_ST	P00533	EGFR	Q15759	MAPK11	S227	S229C	229	Missense	proximal	2	no	34.848	32.853	EPSD	TCGA;COSMIC	33.886	Loss
CMGC_MAPK_p38_MAPK11_ST	P00533	EGFR	Q15759	MAPK11	S227	C223Y	223	Missense	distal	-4	no	34.848	36.679	EPSD	TCGA;COSMIC	33.886	Up-regulation
CMGC_MAPK_p38_MAPK11_ST	P00533	EGFR	Q15759	MAPK11	S227	R222L	222	Missense	distal	-5	no	34.848	34.760	EPSD	TCGA;COSMIC	33.886	Down-regulation
CMGC_MAPK_p38_MAPK11_ST	P00533	EGFR	Q15759	MAPK11	S227	S227F	227	Missense	central	0	yes	34.848	0.000	EPSD	TCGA;COSMIC	33.886	Loss
CMGC_MAPK_p38_MAPK11_ST	P00533	EGFR	Q15759	MAPK11	S227	P228L	228	Missense	proximal	1	no	34.848	25.030	EPSD	TCGA;COSMIC	33.886	Loss
CMGC_MAPK_p38_MAPK11_ST	P00533	EGFR	Q15759	MAPK11	S227	N234S	234	Missense	distal	7	no	34.848	35.495	EPSD	TCGA;COSMIC	33.886	Up-regulation
CMGC_MAPK_p38_MAPK11_ST	P00533	EGFR	Q15759	MAPK11	S227	R224H	224	Missense	distal	-3	no	34.848	35.186	EPSD	TCGA;COSMIC	33.886	Up-regulation
CMGC_MAPK_p38_MAPK11_ST	P00533	EGFR	Q15759	MAPK11	S511	P512S	512	Missense	proximal	1	no	42.006	26.508	EPSD	TCGA;COSMIC	33.886	Loss
CMGC_MAPK_p38_MAPK11_ST	P00533	EGFR	Q15759	MAPK11	T693	P699L	699	Missense	distal	6	no	43.228	43.265	EPSD	TCGA;COSMIC	33.886	Up-regulation
CMGC_MAPK_p38_MAPK11_ST	P00533	EGFR	Q15759	MAPK11	S752	I759N	759	Missense	distal	7	no	45.508	46.175	EPSD	TCGA;COSMIC	33.886	Up-regulation
CMGC_MAPK_p38_MAPK11_ST	P00533	EGFR	Q15759	MAPK11	S752	K754E	754	Missense	proximal	2	no	45.508	44.941	EPSD	TCGA;COSMIC	33.886	Down-regulation
CMGC_MAPK_p38_MAPK11_ST	P00533	EGFR	Q15759	MAPK11	S752	K754I	754	Missense	proximal	2	no	45.508	43.362	EPSD	TCGA;COSMIC	33.886	Down-regulation
CMGC_MAPK_p38_MAPK11_ST	P00533	EGFR	Q15759	MAPK11	S752	P753L	753	Missense	proximal	1	no	45.508	35.691	EPSD	TCGA;COSMIC	33.886	Down-regulation
CMGC_MAPK_p38_MAPK11_ST	P00533	EGFR	Q15759	MAPK11	S752	P753S	753	Missense	proximal	1	no	45.508	30.010	EPSD	TCGA;COSMIC;GDSC;CCLE	33.886	Loss
CMGC_MAPK_p38_MAPK11_ST	P00533	EGFR	Q15759	MAPK11	S991	F997V	997	Missense	distal	6	no	37.298	37.279	EPSD	TCGA;COSMIC	33.886	Down-regulation
CMGC_MAPK_p38_MAPK11_ST	P00533	EGFR	Q15759	MAPK11	S1026	T1032S	1032	Missense	distal	6	no	47.162	47.175	EPSD	TCGA;COSMIC	33.886	Up-regulation
CMGC_MAPK_p38_MAPK11_ST	P00533	EGFR	Q15759	MAPK11	S1026	P1019L	1019	Missense	distal	-7	no	47.162	47.076	EPSD	TCGA;COSMIC	33.886	Down-regulation
CMGC_MAPK_p38_MAPK11_ST	P00533	EGFR	Q15759	MAPK11	S1026	R1031Q	1031	Missense	distal	5	no	47.162	46.960	EPSD	TCGA;COSMIC	33.886	Down-regulation
CMGC_MAPK_p38_MAPK11_ST	P00533	EGFR	Q15759	MAPK11	T1032	R1031Q	1031	Missense	proximal	-1	no	35.865	35.807	EPSD	TCGA;COSMIC	33.886	Down-regulation
CMGC_MAPK_p38_MAPK11_ST	P00533	EGFR	Q15759	MAPK11	S1037	T1032S	1032	Missense	distal	-5	no	36.856	36.935	EPSD	TCGA;COSMIC	33.886	Up-regulation
CMGC_MAPK_p38_MAPK11_ST	P00533	EGFR	Q15759	MAPK11	S1037	S1042N	1042	Missense	distal	5	no	36.856	37.454	EPSD	TCGA;COSMIC	33.886	Up-regulation
CMGC_MAPK_p38_MAPK11_ST	P00533	EGFR	Q15759	MAPK11	S1037	R1031Q	1031	Missense	distal	-6	no	36.856	36.811	EPSD	TCGA;COSMIC	33.886	Down-regulation
CMGC_MAPK_p38_MAPK11_ST	P00533	EGFR	Q15759	MAPK11	S1039	T1032S	1032	Missense	distal	-7	no	46.998	47.020	PhosphoSitePlus;EPSD	TCGA;COSMIC	33.886	Up-regulation
CMGC_MAPK_p38_MAPK11_ST	P00533	EGFR	Q15759	MAPK11	S1039	S1042N	1042	Missense	distal	3	no	46.998	46.375	PhosphoSitePlus;EPSD	TCGA;COSMIC	33.886	Down-regulation
CMGC_MAPK_p38_MAPK11_ST	P00533	EGFR	Q15759	MAPK11	T1041	S1042N	1042	Missense	proximal	1	no	45.985	20.054	EPSD;PhosphoSitePlus	TCGA;COSMIC	33.886	Loss
CMGC_MAPK_p38_MAPK11_ST	Q8IW41	MAPKAPK5	Q15759	MAPK11	T182	T182P	182	Missense	central	0	yes	48.021	0.000	PhosphoSitePlus	TCGA;ICGC;COSMIC	33.886	Loss
CMGC_MAPK_p38_MAPK11_ST	Q8IW41	MAPKAPK5	Q15759	MAPK11	T182	G178S	178	Missense	distal	-4	no	48.021	50.025	PhosphoSitePlus	TCGA;ICGC;COSMIC	33.886	Up-regulation
CMGC_MAPK_p38_MAPK11_ST	Q8IW41	MAPKAPK5	Q15759	MAPK11	T186	T182P	182	Missense	distal	-4	no	41.298	40.177	EPSD	TCGA;ICGC;COSMIC	33.886	Down-regulation
CMGC_MAPK_p38_MAPK11_ST	Q8IW41	MAPKAPK5	Q15759	MAPK11	S212	T214M	214	Missense	proximal	2	no	39.481	37.170	EPSD	TCGA;ICGC;COSMIC	33.886	Down-regulation
CMGC_MAPK_p38_MAPK11_ST	Q8IW41	MAPKAPK5	Q15759	MAPK11	T214	T214M	214	Missense	central	0	yes	41.160	0.000	EPSD	TCGA;ICGC;COSMIC	33.886	Loss
CMGC_MAPK_p38_MAPK11_ST	Q8IW41	MAPKAPK5	Q15759	MAPK11	S348	D344N	344	Missense	distal	-4	no	33.722	34.246	EPSD	TCGA;ICGC;COSMIC	33.886	Gain
CMGC_MAPK_p38_MAPK11_ST	Q8IW41	MAPKAPK5	Q15759	MAPK11	S348	L352P	352	Missense	distal	4	no	33.722	34.945	EPSD	TCGA;ICGC;COSMIC	33.886	Gain
CMGC_MAPK_p38_MAPK11_ST	P30305	CDC25B	Q15759	MAPK11	S50	S49A	49	Missense	proximal	-1	no	35.045	35.135	EPSD	TCGA;ICGC;COSMIC	33.886	Up-regulation
CMGC_MAPK_p38_MAPK11_ST	P30305	CDC25B	Q15759	MAPK11	T54	S49A	49	Missense	distal	-5	no	35.036	34.952	EPSD	TCGA;ICGC;COSMIC	33.886	Down-regulation
CMGC_MAPK_p38_MAPK11_ST	P30305	CDC25B	Q15759	MAPK11	S115	G110C	110	Missense	distal	-5	no	53.047	52.748	EPSD	TCGA;ICGC;COSMIC	33.886	Down-regulation
CMGC_MAPK_p38_MAPK11_ST	P30305	CDC25B	Q15759	MAPK11	S115	G110D	110	Missense	distal	-5	no	53.047	53.005	EPSD	TCGA;COSMIC	33.886	Down-regulation
CMGC_MAPK_p38_MAPK11_ST	P30305	CDC25B	Q15759	MAPK11	S115	S115F	115	Missense	central	0	yes	53.047	0.000	EPSD	TCGA;COSMIC	33.886	Loss
CMGC_MAPK_p38_MAPK11_ST	P30305	CDC25B	Q15759	MAPK11	S117	G110C	110	Missense	distal	-7	no	43.493	43.343	EPSD	TCGA;ICGC;COSMIC	33.886	Down-regulation
CMGC_MAPK_p38_MAPK11_ST	P30305	CDC25B	Q15759	MAPK11	S117	G110D	110	Missense	distal	-7	no	43.493	43.516	EPSD	TCGA;COSMIC	33.886	Up-regulation
CMGC_MAPK_p38_MAPK11_ST	P30305	CDC25B	Q15759	MAPK11	S117	S115F	115	Missense	proximal	-2	no	43.493	42.382	EPSD	TCGA;COSMIC	33.886	Down-regulation
CMGC_MAPK_p38_MAPK11_ST	P30305	CDC25B	Q15759	MAPK11	S160	S160I	160	Missense	central	0	yes	34.688	0.000	EPSD	TCGA	33.886	Loss
CMGC_MAPK_p38_MAPK11_ST	P30305	CDC25B	Q15759	MAPK11	S160	S160C	160	Missense	central	0	yes	34.688	0.000	EPSD	TCGA;COSMIC	33.886	Loss
CMGC_MAPK_p38_MAPK11_ST	P30305	CDC25B	Q15759	MAPK11	S160	P153L	153	Missense	distal	-7	no	34.688	34.602	EPSD	TCGA;ICGC;COSMIC	33.886	Down-regulation
CMGC_MAPK_p38_MAPK11_ST	P30305	CDC25B	Q15759	MAPK11	S160	V162M	162	Missense	proximal	2	no	34.688	34.762	EPSD	TCGA;ICGC;COSMIC	33.886	Up-regulation
CMGC_MAPK_p38_MAPK11_ST	P30305	CDC25B	Q15759	MAPK11	S160	R164Q	164	Missense	distal	4	no	34.688	34.656	EPSD	TCGA	33.886	Down-regulation
CMGC_MAPK_p38_MAPK11_ST	P30305	CDC25B	Q15759	MAPK11	S186	E193D	193	Missense	distal	7	no	36.692	36.354	EPSD	TCGA	33.886	Down-regulation
CMGC_MAPK_p38_MAPK11_ST	P30305	CDC25B	Q15759	MAPK11	S186	D191H	191	Missense	distal	5	no	36.692	36.726	EPSD	TCGA;COSMIC	33.886	Up-regulation
CMGC_MAPK_p38_MAPK11_ST	P30305	CDC25B	Q15759	MAPK11	S238	D240H	240	Missense	proximal	2	no	38.938	38.548	EPSD	TCGA;ICGC	33.886	Down-regulation
CMGC_MAPK_p38_MAPK11_ST	P30305	CDC25B	Q15759	MAPK11	S238	V245M	245	Missense	distal	7	no	38.938	39.365	EPSD	TCGA;COSMIC	33.886	Up-regulation
CMGC_MAPK_p38_MAPK11_ST	P30305	CDC25B	Q15759	MAPK11	S238	S238R	238	Missense	central	0	yes	38.938	0.000	EPSD	TCGA;ICGC;COSMIC;CCLE	33.886	Loss
CMGC_MAPK_p38_MAPK11_ST	P30305	CDC25B	Q15759	MAPK11	S238	L237I	237	Missense	proximal	-1	no	38.938	38.131	EPSD	TCGA	33.886	Down-regulation
CMGC_MAPK_p38_MAPK11_ST	P30305	CDC25B	Q15759	MAPK11	S238	R241Q	241	Missense	distal	3	no	38.938	38.751	EPSD	TCGA;ICGC	33.886	Down-regulation
CMGC_MAPK_p38_MAPK11_ST	P30305	CDC25B	Q15759	MAPK11	S249	V245M	245	Missense	distal	-4	no	45.401	45.321	PhosphoSitePlus	TCGA;COSMIC	33.886	Down-regulation
CMGC_MAPK_p38_MAPK11_ST	P30305	CDC25B	Q15759	MAPK11	S321	R317Q	317	Missense	distal	-4	no	45.485	43.686	EPSD	TCGA;COSMIC	33.886	Down-regulation
CMGC_MAPK_p38_MAPK11_ST	P30305	CDC25B	Q15759	MAPK11	T355	E358K	358	Missense	distal	3	no	40.945	41.527	EPSD	TCGA;ICGC;COSMIC	33.886	Up-regulation
CMGC_MAPK_p38_MAPK11_ST	P30305	CDC25B	Q15759	MAPK11	T355	R352W	352	Missense	distal	-3	no	40.945	41.284	EPSD	TCGA;ICGC;COSMIC	33.886	Up-regulation
CMGC_MAPK_p38_MAPK11_ST	P30305	CDC25B	Q15759	MAPK11	S375	E380Q	380	Missense	distal	5	no	37.282	37.055	EPSD	TCGA;COSMIC	33.886	Down-regulation
CMGC_MAPK_p38_MAPK11_ST	P30305	CDC25B	Q15759	MAPK11	S375	S373T	373	Missense	proximal	-2	no	37.282	37.478	EPSD	TCGA;ICGC;COSMIC	33.886	Up-regulation
CMGC_MAPK_p38_MAPK11_ST	P30305	CDC25B	Q15759	MAPK11	S375	R369H	369	Missense	distal	-6	no	37.282	37.208	EPSD	TCGA;COSMIC	33.886	Down-regulation
CMGC_MAPK_p38_MAPK11_ST	P30305	CDC25B	Q15759	MAPK11	S470	E464D	464	Missense	distal	-6	no	41.932	41.862	EPSD	TCGA;ICGC	33.886	Down-regulation
CMGC_MAPK_p38_MAPK11_ST	P30305	CDC25B	Q15759	MAPK11	S470	A463V	463	Missense	distal	-7	no	41.932	41.869	EPSD	TCGA;ICGC;COSMIC	33.886	Down-regulation
CMGC_MAPK_p38_MAPK11_ST	P41235	HNF4A	Q15759	MAPK11	S147	A154V	154	Missense	distal	7	no	37.117	36.725	EPSD	TCGA;ICGC;COSMIC	33.886	Down-regulation
CMGC_MAPK_p38_MAPK11_ST	P41235	HNF4A	Q15759	MAPK11	S147	N153D	153	Missense	distal	6	no	37.117	37.105	EPSD	TCGA;ICGC;COSMIC	33.886	Down-regulation
CMGC_MAPK_p38_MAPK11_ST	P41235	HNF4A	Q15759	MAPK11	S147	S151Y	151	Missense	distal	4	no	37.117	36.014	EPSD	TCGA;COSMIC	33.886	Down-regulation
CMGC_MAPK_p38_MAPK11_ST	P41235	HNF4A	Q15759	MAPK11	S167	V160F	160	Missense	distal	-7	no	47.102	47.084	PhosphoSitePlus	TCGA	33.886	Down-regulation
CMGC_MAPK_p38_MAPK11_ST	P41235	HNF4A	Q15759	MAPK11	S167	S170C	170	Missense	distal	3	no	47.102	45.047	PhosphoSitePlus	TCGA;COSMIC	33.886	Down-regulation
CMGC_MAPK_p38_MAPK11_ST	P41235	HNF4A	Q15759	MAPK11	S167	G174S	174	Missense	distal	7	no	47.102	47.733	PhosphoSitePlus	TCGA;ICGC;COSMIC	33.886	Up-regulation
CMGC_MAPK_p38_MAPK11_ST	P41235	HNF4A	Q15759	MAPK11	S378	D381N	381	Missense	distal	3	no	41.933	41.554	EPSD	TCGA;ICGC;COSMIC	33.886	Down-regulation
CMGC_MAPK_p38_MAPK11_ST	P41235	HNF4A	Q15759	MAPK11	S378	A382S	382	Missense	distal	4	no	41.933	42.315	EPSD	TCGA;ICGC;COSMIC	33.886	Up-regulation
CMGC_MAPK_p38_MAPK11_ST	P41235	HNF4A	Q15759	MAPK11	S378	H384N	384	Missense	distal	6	no	41.933	41.930	EPSD	TCGA;COSMIC	33.886	Down-regulation
CMGC_MAPK_p38_MAPK11_ST	P41235	HNF4A	Q15759	MAPK11	S378	G377E	377	Missense	proximal	-1	no	41.933	42.002	EPSD	TCGA;ICGC;COSMIC	33.886	Up-regulation
CMGC_MAPK_p38_MAPK11_ST	P41235	HNF4A	Q15759	MAPK11	S378	S380N	380	Missense	proximal	2	no	41.933	41.720	EPSD	TCGA;COSMIC	33.886	Down-regulation
CMGC_MAPK_p38_MAPK11_ST	P41235	HNF4A	Q15759	MAPK11	S378	G376R	376	Missense	proximal	-2	no	41.933	41.956	EPSD	TCGA;ICGC;COSMIC	33.886	Up-regulation
CMGC_MAPK_p38_MAPK11_ST	P41235	HNF4A	Q15759	MAPK11	S378	S380G	380	Missense	proximal	2	no	41.933	39.895	EPSD	TCGA;COSMIC	33.886	Down-regulation
CMGC_MAPK_p38_MAPK11_ST	P41235	HNF4A	Q15759	MAPK11	S378	D381V	381	Missense	distal	3	no	41.933	40.683	EPSD	TCGA;ICGC;COSMIC	33.886	Down-regulation
CMGC_MAPK_p38_MAPK11_ST	P41235	HNF4A	Q15759	MAPK11	T429	P433S	433	Missense	distal	4	no	35.953	36.356	EPSD	TCGA;COSMIC	33.886	Up-regulation
CMGC_MAPK_p38_MAPK11_ST	P41235	HNF4A	Q15759	MAPK11	T429	G425R	425	Missense	distal	-4	no	35.953	37.199	EPSD	TCGA;COSMIC	33.886	Up-regulation
CMGC_MAPK_p38_MAPK11_ST	P41235	HNF4A	Q15759	MAPK11	T429	R422Q	422	Missense	distal	-7	no	35.953	35.839	EPSD	TCGA;COSMIC	33.886	Down-regulation
CMGC_MAPK_p38_MAPK11_ST	P41235	HNF4A	Q15759	MAPK11	T429	T432I	432	Missense	distal	3	no	35.953	34.046	EPSD	TCGA;COSMIC	33.886	Down-regulation
CMGC_MAPK_p38_MAPK11_ST	P41235	HNF4A	Q15759	MAPK11	T432	P433S	433	Missense	proximal	1	no	43.031	27.532	EPSD	TCGA;COSMIC	33.886	Loss
CMGC_MAPK_p38_MAPK11_ST	P41235	HNF4A	Q15759	MAPK11	T432	G425R	425	Missense	distal	-7	no	43.031	43.078	EPSD	TCGA;COSMIC	33.886	Up-regulation
CMGC_MAPK_p38_MAPK11_ST	P41235	HNF4A	Q15759	MAPK11	T432	T432I	432	Missense	central	0	yes	43.031	0.000	EPSD	TCGA;COSMIC	33.886	Loss
CMGC_MAPK_p38_MAPK11_ST	P41235	HNF4A	Q15759	MAPK11	S436	S443Y	443	Missense	distal	7	no	35.117	34.545	EPSD	TCGA;COSMIC	33.886	Down-regulation
CMGC_MAPK_p38_MAPK11_ST	P41235	HNF4A	Q15759	MAPK11	S436	P433S	433	Missense	distal	-3	no	35.117	34.975	EPSD	TCGA;COSMIC	33.886	Down-regulation
CMGC_MAPK_p38_MAPK11_ST	P41235	HNF4A	Q15759	MAPK11	S436	G442E	442	Missense	distal	6	no	35.117	35.086	EPSD	TCGA;COSMIC	33.886	Down-regulation
CMGC_MAPK_p38_MAPK11_ST	P41235	HNF4A	Q15759	MAPK11	S436	T432I	432	Missense	distal	-4	no	35.117	32.479	EPSD	TCGA;COSMIC	33.886	Loss
CMGC_MAPK_p38_MAPK11_ST	P17544	ATF7	Q15759	MAPK11	T51	T53N	53	Missense	proximal	2	no	48.874	48.466	PhosphoSitePlus	TCGA;ICGC	33.886	Down-regulation
CMGC_MAPK_p38_MAPK11_ST	P17544	ATF7	Q15759	MAPK11	T53	K59N	59	Missense	distal	6	no	52.229	52.274	EPSD	TCGA;ICGC;COSMIC	33.886	Up-regulation
CMGC_MAPK_p38_MAPK11_ST	P17544	ATF7	Q15759	MAPK11	T53	T53N	53	Missense	central	0	yes	52.229	0.000	EPSD	TCGA;ICGC	33.886	Loss
CMGC_MAPK_p38_MAPK11_ST	P17544	ATF7	Q15759	MAPK11	S128	P129L	129	Missense	proximal	1	no	37.974	28.156	EPSD	TCGA	33.886	Loss
CMGC_MAPK_p38_MAPK11_ST	P17544	ATF7	Q15759	MAPK11	S128	P122A	122	Missense	distal	-6	no	37.974	37.930	EPSD	TCGA;ICGC;COSMIC	33.886	Down-regulation
CMGC_MAPK_p38_MAPK11_ST	P17544	ATF7	Q15759	MAPK11	S132	P129L	129	Missense	distal	-3	no	36.141	36.559	EPSD	TCGA	33.886	Up-regulation
CMGC_MAPK_p38_MAPK11_ST	P17544	ATF7	Q15759	MAPK11	S136	P129L	129	Missense	distal	-7	no	42.677	42.592	EPSD	TCGA	33.886	Down-regulation
CMGC_MAPK_p38_MAPK11_ST	P17544	ATF7	Q15759	MAPK11	T148	S155F	155	Missense	distal	7	no	51.979	50.959	EPSD	TCGA;COSMIC	33.886	Down-regulation
CMGC_MAPK_p38_MAPK11_ST	P17544	ATF7	Q15759	MAPK11	T156	S155F	155	Missense	proximal	-1	no	38.937	38.069	EPSD	TCGA;COSMIC	33.886	Down-regulation
CMGC_MAPK_p38_MAPK11_ST	P17544	ATF7	Q15759	MAPK11	T158	S155F	155	Missense	distal	-3	no	43.279	44.099	EPSD	TCGA;COSMIC	33.886	Up-regulation
CMGC_MAPK_p38_MAPK11_ST	P17544	ATF7	Q15759	MAPK11	T327	R334Q	334	Missense	distal	7	no	44.232	43.986	EPSD	TCGA;COSMIC	33.886	Down-regulation
CMGC_MAPK_p38_MAPK11_ST	P13807	GYS1	Q15759	MAPK11	S645	P644L	644	Missense	proximal	-1	no	49.264	48.910	EPSD;PhosphoSitePlus	TCGA;COSMIC	33.886	Down-regulation
CMGC_MAPK_p38_MAPK11_ST	P13807	GYS1	Q15759	MAPK11	S645	S647L	647	Missense	proximal	2	no	49.264	48.339	EPSD;PhosphoSitePlus	TCGA;COSMIC	33.886	Down-regulation
CMGC_MAPK_p38_MAPK11_ST	P13807	GYS1	Q15759	MAPK11	S647	P644L	644	Missense	distal	-3	no	35.853	36.271	EPSD	TCGA;COSMIC	33.886	Up-regulation
CMGC_MAPK_p38_MAPK11_ST	P13807	GYS1	Q15759	MAPK11	S647	S647L	647	Missense	central	0	yes	35.853	0.000	EPSD	TCGA;COSMIC	33.886	Loss
CMGC_MAPK_p38_MAPK11_ST	P13807	GYS1	Q15759	MAPK11	S653	S647L	647	Missense	distal	-6	no	47.120	46.964	EPSD;PhosphoSitePlus	TCGA;COSMIC	33.886	Down-regulation
CMGC_MAPK_p38_MAPK11_ST	P13807	GYS1	Q15759	MAPK11	T713	S720G	720	Missense	distal	7	no	41.768	41.137	EPSD	TCGA;COSMIC	33.886	Down-regulation
CMGC_MAPK_p38_MAPK11_ST	P13807	GYS1	Q15759	MAPK11	T713	L719I	719	Missense	distal	6	no	41.768	41.830	EPSD	TCGA;COSMIC	33.886	Up-regulation
CMGC_MAPK_p38_MAPK11_ST	P13807	GYS1	Q15759	MAPK11	T715	S720G	720	Missense	distal	5	no	37.151	37.705	EPSD	TCGA;COSMIC	33.886	Up-regulation
CMGC_MAPK_p38_MAPK11_ST	P13807	GYS1	Q15759	MAPK11	T715	L719I	719	Missense	distal	4	no	37.151	35.974	EPSD	TCGA;COSMIC	33.886	Down-regulation
CMGC_MAPK_p38_MAPK11_ST	P13807	GYS1	Q15759	MAPK11	S717	S720G	720	Missense	distal	3	no	35.331	35.112	EPSD	TCGA;COSMIC	33.886	Down-regulation
CMGC_MAPK_p38_MAPK11_ST	P13807	GYS1	Q15759	MAPK11	S717	L719I	719	Missense	proximal	2	no	35.331	33.288	EPSD	TCGA;COSMIC	33.886	Loss
CMGC_MAPK_p38_MAPK11_ST	P13807	GYS1	Q15759	MAPK11	S718	S720G	720	Missense	proximal	2	no	38.533	36.494	EPSD	TCGA;COSMIC	33.886	Down-regulation
CMGC_MAPK_p38_MAPK11_ST	P13807	GYS1	Q15759	MAPK11	S718	L719I	719	Missense	proximal	1	no	38.533	-0.441	EPSD	TCGA;COSMIC	33.886	Loss
CMGC_MAPK_p38_MAPK11_ST	P13807	GYS1	Q15759	MAPK11	T721	S720G	720	Missense	proximal	-1	no	47.813	47.907	EPSD;PhosphoSitePlus	TCGA;COSMIC	33.886	Up-regulation
CMGC_MAPK_p38_MAPK11_ST	P13807	GYS1	Q15759	MAPK11	T721	L719I	719	Missense	proximal	-2	no	47.813	47.059	EPSD;PhosphoSitePlus	TCGA;COSMIC	33.886	Down-regulation
CMGC_MAPK_p38_MAPK11_ST	P13807	GYS1	Q15759	MAPK11	S727	S720G	720	Missense	distal	-7	no	56.521	56.378	PhosphoSitePlus;EPSD	TCGA;COSMIC	33.886	Down-regulation
CMGC_MAPK_p38_MAPK11_ST	P13807	GYS1	Q15759	MAPK11	S727	G733C	733	Missense	distal	6	no	56.521	56.586	PhosphoSitePlus;EPSD	TCGA;COSMIC	33.886	Up-regulation
CMGC_MAPK_p38_MAPK11_ST	P13807	GYS1	Q15759	MAPK11	T729	G733C	733	Missense	distal	4	no	37.500	35.429	EPSD	TCGA;COSMIC	33.886	Down-regulation
CMGC_MAPK_p38_MAPK11_ST	P13807	GYS1	Q15759	MAPK11	S731	G733C	733	Missense	proximal	2	no	40.841	40.886	EPSD	TCGA;COSMIC	33.886	Up-regulation
CMGC_MAPK_p38_MAPK11_ST	Q02156	PRKCE	Q15759	MAPK11	T309	D305Y	305	Missense	distal	-4	no	43.170	42.658	EPSD	TCGA;ICGC;COSMIC	33.886	Down-regulation
CMGC_MAPK_p38_MAPK11_ST	Q02156	PRKCE	Q15759	MAPK11	T309	D305N	305	Missense	distal	-4	no	43.170	43.693	EPSD	TCGA;ICGC;COSMIC	33.886	Up-regulation
CMGC_MAPK_p38_MAPK11_ST	Q02156	PRKCE	Q15759	MAPK11	T309	P310L	310	Missense	proximal	1	no	43.170	33.352	EPSD	TCGA;ICGC;COSMIC	33.886	Loss
CMGC_MAPK_p38_MAPK11_ST	Q02156	PRKCE	Q15759	MAPK11	T309	V308I	308	Missense	proximal	-1	no	43.170	42.715	EPSD	TCGA;ICGC;COSMIC	33.886	Down-regulation
CMGC_MAPK_p38_MAPK11_ST	Q02156	PRKCE	Q15759	MAPK11	T309	L306M	306	Missense	distal	-3	no	43.170	42.604	EPSD	TCGA;ICGC;COSMIC	33.886	Down-regulation
CMGC_MAPK_p38_MAPK11_ST	Q02156	PRKCE	Q15759	MAPK11	S337	E341K	341	Missense	distal	4	no	34.854	35.051	EPSD	TCGA;ICGC;COSMIC	33.886	Up-regulation
CMGC_MAPK_p38_MAPK11_ST	Q02156	PRKCE	Q15759	MAPK11	S346	E341K	341	Missense	distal	-5	no	42.139	42.155	EPSD	TCGA;ICGC;COSMIC	33.886	Up-regulation
CMGC_MAPK_p38_MAPK11_ST	Q02156	PRKCE	Q15759	MAPK11	S381	S381F	381	Missense	central	0	yes	48.729	0.000	EPSD	TCGA;ICGC	33.886	Loss
CMGC_MAPK_p38_MAPK11_ST	Q02156	PRKCE	Q15759	MAPK11	S381	S388R	388	Missense	distal	7	no	48.729	48.104	EPSD	TCGA;ICGC;COSMIC	33.886	Down-regulation
CMGC_MAPK_p38_MAPK11_ST	Q02156	PRKCE	Q15759	MAPK11	S381	R377L	377	Missense	distal	-4	no	48.729	46.198	EPSD	TCGA;ICGC;COSMIC	33.886	Down-regulation
CMGC_MAPK_p38_MAPK11_ST	Q02156	PRKCE	Q15759	MAPK11	S381	E374K	374	Missense	distal	-7	no	48.729	48.816	EPSD	TCGA;ICGC;COSMIC	33.886	Up-regulation
CMGC_MAPK_p38_MAPK11_ST	Q02156	PRKCE	Q15759	MAPK11	S388	S381F	381	Missense	distal	-7	no	39.349	39.102	EPSD	TCGA;ICGC	33.886	Down-regulation
CMGC_MAPK_p38_MAPK11_ST	Q02156	PRKCE	Q15759	MAPK11	S388	S388R	388	Missense	central	0	yes	39.349	0.000	EPSD	TCGA;ICGC;COSMIC	33.886	Loss
CMGC_MAPK_p38_MAPK11_ST	Q01844	EWSR1	Q15759	MAPK11	T79	T79I	79	Missense	central	0	yes	48.696	0.000	PhosphoSitePlus	TCGA;ICGC;COSMIC	33.886	Loss
CMGC_MAPK_p38_MAPK11_ST	P30281	CCND3	Q15759	MAPK11	S133	I126M	126	Missense	distal	-7	no	42.758	42.895	EPSD	TCGA;COSMIC	33.886	Up-regulation
CMGC_MAPK_p38_MAPK11_ST	P30281	CCND3	Q15759	MAPK11	S133	R135L	135	Missense	proximal	2	no	42.758	42.578	EPSD	TCGA;COSMIC	33.886	Down-regulation
CMGC_MAPK_p38_MAPK11_ST	P30281	CCND3	Q15759	MAPK11	S262	Q260E	260	Missense	proximal	-2	no	33.567	33.922	EPSD	TCGA;COSMIC	33.886	Gain
CMGC_MAPK_p38_MAPK11_ST	P30281	CCND3	Q15759	MAPK11	S263	P265T	265	Missense	proximal	2	no	32.863	34.247	EPSD	TCGA;COSMIC	33.886	Gain
CMGC_MAPK_p38_MAPK11_ST	P30281	CCND3	Q15759	MAPK11	S264	P265T	265	Missense	proximal	1	no	37.891	13.306	EPSD	TCGA;COSMIC	33.886	Loss
CMGC_MAPK_p38_MAPK11_ST	P30281	CCND3	Q15759	MAPK11	S264	S263C	263	Missense	proximal	-1	no	37.891	37.034	EPSD	TCGA;COSMIC	33.886	Down-regulation
CMGC_MAPK_p38_MAPK11_ST	P30281	CCND3	Q15759	MAPK11	S264	Q260E	260	Missense	distal	-4	no	37.891	38.475	EPSD	TCGA;COSMIC	33.886	Up-regulation
CMGC_MAPK_p38_MAPK11_ST	P30281	CCND3	Q15759	MAPK11	S264	T261S	261	Missense	distal	-3	no	37.891	37.559	EPSD	TCGA;ICGC;COSMIC	33.886	Down-regulation
CMGC_MAPK_p38_MAPK11_ST	P30281	CCND3	Q15759	MAPK11	S264	A266V	266	Missense	proximal	2	no	37.891	38.086	EPSD	TCGA;ICGC;COSMIC;GDSC	33.886	Up-regulation
CMGC_MAPK_p38_MAPK11_ST	P30281	CCND3	Q15759	MAPK11	T281	P278R	278	Missense	distal	-3	no	34.875	35.118	EPSD	TCGA;COSMIC	33.886	Up-regulation
CMGC_MAPK_p38_MAPK11_ST	P30281	CCND3	Q15759	MAPK11	T281	T283A	283	Missense	proximal	2	no	34.875	32.293	EPSD	TCGA;ICGC;COSMIC;CCLE	33.886	Loss
CMGC_MAPK_p38_MAPK11_ST	P30281	CCND3	Q15759	MAPK11	T281	V287I	287	Missense	distal	6	no	34.875	34.925	EPSD	TCGA;COSMIC	33.886	Up-regulation
CMGC_MAPK_p38_MAPK11_ST	P30281	CCND3	Q15759	MAPK11	S282	T283A	283	Missense	proximal	1	no	27.607	43.156	EPSD	TCGA;ICGC;COSMIC;CCLE	33.886	Gain
CMGC_MAPK_p38_MAPK11_ST	P30281	CCND3	Q15759	MAPK11	T283	P278R	278	Missense	distal	-5	no	51.057	51.005	PhosphoSitePlus	TCGA;COSMIC	33.886	Down-regulation
CMGC_MAPK_p38_MAPK11_ST	P30281	CCND3	Q15759	MAPK11	T283	T283A	283	Missense	central	0	yes	51.057	0.000	PhosphoSitePlus	TCGA;ICGC;COSMIC;CCLE	33.886	Loss
CMGC_MAPK_p38_MAPK11_ST	P30281	CCND3	Q15759	MAPK11	T283	V287I	287	Missense	distal	4	no	51.057	50.650	PhosphoSitePlus	TCGA;COSMIC	33.886	Down-regulation
CMGC_MAPK_p38_MAPK11_ST	P30281	CCND3	Q15759	MAPK11	T288	T283A	283	Missense	distal	-5	no	38.653	38.649	EPSD	TCGA;ICGC;COSMIC;CCLE	33.886	Down-regulation
CMGC_MAPK_p38_MAPK11_ST	P30281	CCND3	Q15759	MAPK11	T288	V287I	287	Missense	proximal	-1	no	38.653	38.198	EPSD	TCGA;COSMIC	33.886	Down-regulation
CMGC_MAPK_p38_MAPK11_ST	P04150	NR3C1	Q15759	MAPK11	S45	A51T	51	Missense	distal	6	no	37.002	36.969	EPSD	TCGA;ICGC;COSMIC	33.886	Down-regulation
CMGC_MAPK_p38_MAPK11_ST	P04150	NR3C1	Q15759	MAPK11	S45	S42Y	42	Missense	distal	-3	no	37.002	37.393	EPSD	TCGA;ICGC;COSMIC	33.886	Up-regulation
CMGC_MAPK_p38_MAPK11_ST	P04150	NR3C1	Q15759	MAPK11	T145	K140N	140	Missense	distal	-5	no	37.721	37.456	EPSD	TCGA;ICGC;COSMIC	33.886	Down-regulation
CMGC_MAPK_p38_MAPK11_ST	P04150	NR3C1	Q15759	MAPK11	S211	P212H	212	Missense	proximal	1	no	51.399	10.337	EPSD	TCGA;ICGC;COSMIC	33.886	Loss
CMGC_MAPK_p38_MAPK11_ST	P04150	NR3C1	Q15759	MAPK11	S226	N222T	222	Missense	distal	-4	no	50.001	50.139	PhosphoSitePlus	TCGA;ICGC;COSMIC	33.886	Up-regulation
CMGC_MAPK_p38_MAPK11_ST	P04150	NR3C1	Q15759	MAPK11	S226	A229V	229	Missense	distal	3	no	50.001	49.483	PhosphoSitePlus	TCGA;ICGC;COSMIC	33.886	Down-regulation
CMGC_MAPK_p38_MAPK11_ST	P04150	NR3C1	Q15759	MAPK11	S226	G230R	230	Missense	distal	4	no	50.001	49.494	PhosphoSitePlus	TCGA;ICGC	33.886	Down-regulation
CMGC_MAPK_p38_MAPK11_ST	P04150	NR3C1	Q15759	MAPK11	S226	I219L	219	Missense	distal	-7	no	50.001	50.072	PhosphoSitePlus	TCGA;ICGC;COSMIC	33.886	Up-regulation
CMGC_MAPK_p38_MAPK11_ST	P04150	NR3C1	Q15759	MAPK11	T288	P289S	289	Missense	proximal	1	no	39.583	24.085	EPSD	TCGA;ICGC;COSMIC	33.886	Loss
CMGC_MAPK_p38_MAPK11_ST	P04150	NR3C1	Q15759	MAPK11	S340	Q344R	344	Missense	distal	4	no	36.454	36.485	EPSD	TCGA;ICGC;COSMIC	33.886	Up-regulation
CMGC_MAPK_p38_MAPK11_ST	P04150	NR3C1	Q15759	MAPK11	S395	S395I	395	Missense	central	0	yes	37.828	0.000	EPSD	TCGA;ICGC	33.886	Loss
CMGC_MAPK_p38_MAPK11_ST	P04150	NR3C1	Q15759	MAPK11	S404	S404Y	404	Missense	central	0	yes	37.425	0.000	EPSD	TCGA;ICGC	33.886	Loss
CMGC_MAPK_p38_MAPK11_ST	P04150	NR3C1	Q15759	MAPK11	S407	S404Y	404	Missense	distal	-3	no	33.686	34.077	EPSD	TCGA;ICGC	33.886	Gain
TK_EGFR_ERBB4_Y	Q15303	ERBB4	Q15303	ERBB4	Y875	Y875F	875	Missense	central	0	yes	0.000	0.000	EPSD	TCGA;COSMIC	0.000	Loss
TK_EGFR_ERBB4_Y	Q15303	ERBB4	Q15303	ERBB4	Y1022	Y1022C	1022	Missense	central	0	yes	0.000	0.000	EPSD	TCGA;COSMIC	0.000	Loss
TK_EGFR_ERBB4_Y	Q15303	ERBB4	Q15303	ERBB4	Y1128	Y1128H	1128	Missense	central	0	yes	0.000	0.000	EPSD	TCGA;COSMIC	0.000	Loss
TK_EGFR_ERBB4_Y	Q15303	ERBB4	Q15303	ERBB4	Y1150	Y1150C	1150	Missense	central	0	yes	0.000	0.000	EPSD	TCGA;COSMIC	0.000	Loss
TK_EGFR_ERBB4_Y	Q15303	ERBB4	Q15303	ERBB4	Y1242	Y1242F	1242	Missense	central	0	yes	0.000	0.000	EPSD	TCGA;COSMIC	0.000	Loss
Other_NKF2_PINK1_ST	Q6NUN9	ZNF746	Q9BXM7	PINK1	T278	A276T	276	Missense	proximal	-2	no	12.917	11.331	EPSD	TCGA;ICGC;COSMIC	11.649	Loss
Other_NKF2_PINK1_ST	O95202	LETM1	Q9BXM7	PINK1	S126	L124F	124	Missense	proximal	-2	no	8.305	12.063	EPSD	TCGA;ICGC;COSMIC	11.649	Gain
Other_NKF2_PINK1_ST	O95202	LETM1	Q9BXM7	PINK1	T192	G188S	188	Missense	distal	-4	no	25.697	26.094	PhosphoSitePlus	TCGA;ICGC;COSMIC	11.649	Up-regulation
Other_NKF2_PINK1_ST	O95202	LETM1	Q9BXM7	PINK1	T192	R196C	196	Missense	distal	4	no	25.697	25.689	PhosphoSitePlus	TCGA;ICGC	11.649	Down-regulation
Other_NKF2_PINK1_ST	O95202	LETM1	Q9BXM7	PINK1	T192	H189Y	189	Missense	distal	-3	no	25.697	25.889	PhosphoSitePlus	TCGA;ICGC	11.649	Up-regulation
Other_NKF2_PINK1_ST	Q9BXM7	PINK1	Q9BXM7	PINK1	S228	E231K	231	Missense	distal	3	no	26.175	26.778	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	11.649	Up-regulation
Other_NKF2_PINK1_ST	Q9BXM7	PINK1	Q9BXM7	PINK1	S228	S225P	225	Missense	distal	-3	no	26.175	26.263	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	11.649	Up-regulation
Other_NKF2_PINK1_ST	Q9BXM7	PINK1	Q9BXM7	PINK1	S402	G395S	395	Missense	distal	-7	no	24.684	24.616	PhosphoSitePlus;EPSD	TCGA;ICGC	11.649	Down-regulation
Other_NKF2_PINK1_ST	Q9BXM7	PINK1	Q9BXM7	PINK1	S402	G409R	409	Missense	distal	7	no	24.684	24.420	PhosphoSitePlus;EPSD	TCGA;ICGC;COSMIC	11.649	Down-regulation
Other_NKF2_PINK1_ST	Q9BXM7	PINK1	Q9BXM7	PINK1	S402	R407W	407	Missense	distal	5	no	24.684	24.105	PhosphoSitePlus;EPSD	TCGA;ICGC;COSMIC	11.649	Down-regulation
Other_NKF2_PINK1_ST	Q8IXI2	RHOT1	Q9BXM7	PINK1	S156	S156L	156	Missense	central	0	yes	26.785	0.000	PhosphoSitePlus	TCGA;ICGC;COSMIC	11.649	Loss
Other_NKF2_PINK1_ST	Q8IXI2	RHOT1	Q9BXM7	PINK1	S156	N154S	154	Missense	proximal	-2	no	26.785	27.969	PhosphoSitePlus	TCGA;ICGC;COSMIC	11.649	Up-regulation
TKL_RAF_RAF_RAF1_ST	P04049	RAF1	P04049	RAF1	S12	F17S	17	Missense	distal	5	no	9.852	9.297	EPSD	TCGA;ICGC;COSMIC	7.934	Down-regulation
TKL_RAF_RAF_RAF1_ST	P04049	RAF1	P04049	RAF1	S12	D19Y	19	Missense	distal	7	no	9.852	9.231	EPSD	TCGA;ICGC;COSMIC	7.934	Down-regulation
TKL_RAF_RAF_RAF1_ST	P04049	RAF1	P04049	RAF1	T182	D186N	186	Missense	distal	4	no	7.941	8.135	EPSD	TCGA;COSMIC	7.934	Up-regulation
TKL_RAF_RAF_RAF1_ST	P04049	RAF1	P04049	RAF1	S204	N198K	198	Missense	distal	-6	no	10.128	10.074	EPSD	TCGA;ICGC	7.934	Down-regulation
TKL_RAF_RAF_RAF1_ST	P04049	RAF1	P04049	RAF1	S220	R215C	215	Missense	distal	-5	no	8.780	8.478	EPSD	TCGA;ICGC;COSMIC	7.934	Down-regulation
TKL_RAF_RAF_RAF1_ST	P04049	RAF1	P04049	RAF1	S220	R223M	223	Missense	distal	3	no	8.780	8.363	EPSD	TCGA;ICGC;COSMIC	7.934	Down-regulation
TKL_RAF_RAF_RAF1_ST	P04049	RAF1	P04049	RAF1	S220	P225H	225	Missense	distal	5	no	8.780	8.750	EPSD	TCGA;ICGC	7.934	Down-regulation
TKL_RAF_RAF_RAF1_ST	P04049	RAF1	P04049	RAF1	S227	R223M	223	Missense	distal	-4	no	8.404	8.525	EPSD	TCGA;ICGC;COSMIC	7.934	Up-regulation
TKL_RAF_RAF_RAF1_ST	P04049	RAF1	P04049	RAF1	S227	P225H	225	Missense	proximal	-2	no	8.404	8.388	EPSD	TCGA;ICGC	7.934	Down-regulation
TKL_RAF_RAF_RAF1_ST	P04049	RAF1	P04049	RAF1	S257	S257L	257	Missense	central	0	yes	11.654	0.000	EPSD	TCGA;COSMIC;GDSC;CCLE	7.934	Loss
TKL_RAF_RAF_RAF1_ST	P04049	RAF1	P04049	RAF1	S257	P261R	261	Missense	distal	4	no	11.654	11.832	EPSD	TCGA;COSMIC;CCLE	7.934	Up-regulation
TKL_RAF_RAF_RAF1_ST	P04049	RAF1	P04049	RAF1	S257	S257W	257	Missense	central	0	yes	11.654	0.000	EPSD	TCGA;COSMIC	7.934	Loss
TKL_RAF_RAF_RAF1_ST	P04049	RAF1	P04049	RAF1	S257	S259F	259	Missense	proximal	2	no	11.654	10.784	EPSD	TCGA;COSMIC;GDSC;CCLE	7.934	Down-regulation
TKL_RAF_RAF_RAF1_ST	P04049	RAF1	P04049	RAF1	S257	H264Y	264	Missense	distal	7	no	11.654	11.206	EPSD	TCGA;COSMIC	7.934	Down-regulation
TKL_RAF_RAF_RAF1_ST	P04049	RAF1	P04049	RAF1	S259	S257L	257	Missense	proximal	-2	no	15.532	15.626	EPSD;PhosphoSitePlus	TCGA;COSMIC;GDSC;CCLE	7.934	Up-regulation
TKL_RAF_RAF_RAF1_ST	P04049	RAF1	P04049	RAF1	S259	P261R	261	Missense	proximal	2	no	15.532	14.464	EPSD;PhosphoSitePlus	TCGA;COSMIC;CCLE	7.934	Down-regulation
TKL_RAF_RAF_RAF1_ST	P04049	RAF1	P04049	RAF1	S259	S257W	257	Missense	proximal	-2	no	15.532	15.528	EPSD;PhosphoSitePlus	TCGA;COSMIC	7.934	Down-regulation
TKL_RAF_RAF_RAF1_ST	P04049	RAF1	P04049	RAF1	S259	S259F	259	Missense	central	0	yes	15.532	0.000	EPSD;PhosphoSitePlus	TCGA;COSMIC;GDSC;CCLE	7.934	Loss
TKL_RAF_RAF_RAF1_ST	P04049	RAF1	P04049	RAF1	S259	H264Y	264	Missense	distal	5	no	15.532	15.212	EPSD;PhosphoSitePlus	TCGA;COSMIC	7.934	Down-regulation
TKL_RAF_RAF_RAF1_ST	P04049	RAF1	P04049	RAF1	T268	P261R	261	Missense	distal	-7	no	13.672	13.760	EPSD	TCGA;COSMIC;CCLE	7.934	Up-regulation
TKL_RAF_RAF_RAF1_ST	P04049	RAF1	P04049	RAF1	T268	H264Y	264	Missense	distal	-4	no	13.672	12.489	EPSD	TCGA;COSMIC	7.934	Down-regulation
TKL_RAF_RAF_RAF1_ST	P04049	RAF1	P04049	RAF1	S338	R333H	333	Missense	distal	-5	no	14.086	13.761	EPSD;PhosphoSitePlus	TCGA;COSMIC	7.934	Down-regulation
TKL_RAF_RAF_RAF1_ST	P04049	RAF1	P04049	RAF1	S338	S339I	339	Missense	proximal	1	no	14.086	14.321	EPSD;PhosphoSitePlus	TCGA	7.934	Up-regulation
TKL_RAF_RAF_RAF1_ST	P04049	RAF1	P04049	RAF1	S605	E607Q	607	Missense	proximal	2	no	7.264	8.484	EPSD	TCGA;COSMIC	7.934	Gain
TKL_RAF_RAF_RAF1_ST	P04049	RAF1	P04049	RAF1	S621	A620T	620	Missense	proximal	-1	no	15.150	15.058	PhosphoSitePlus;EPSD	TCGA;COSMIC	7.934	Down-regulation
TKL_RAF_RAF_RAF1_ST	P04049	RAF1	P04049	RAF1	S621	R627Q	627	Missense	distal	6	no	15.150	15.268	PhosphoSitePlus;EPSD	TCGA;COSMIC	7.934	Up-regulation
TKL_RAF_RAF_RAF1_ST	Q13118	KLF10	P04049	RAF1	T93	S97N	97	Missense	distal	4	no	13.824	12.515	PhosphoSitePlus	TCGA	7.934	Down-regulation
TKL_RAF_RAF_RAF1_ST	Q13118	KLF10	P04049	RAF1	T93	P94A	94	Missense	proximal	1	no	13.824	13.066	PhosphoSitePlus	TCGA;COSMIC	7.934	Down-regulation
TKL_RAF_RAF_RAF1_ST	Q13118	KLF10	P04049	RAF1	S143	E138K	138	Missense	distal	-5	no	8.635	8.820	EPSD	TCGA;COSMIC	7.934	Up-regulation
TKL_RAF_RAF_RAF1_ST	Q13118	KLF10	P04049	RAF1	S143	P148S	148	Missense	distal	5	no	8.635	7.976	EPSD	TCGA;COSMIC	7.934	Down-regulation
TKL_RAF_RAF_RAF1_ST	Q13118	KLF10	P04049	RAF1	S353	P359L	359	Missense	distal	6	no	8.658	9.254	EPSD	TCGA;COSMIC	7.934	Up-regulation
TKL_RAF_RAF_RAF1_ST	Q13118	KLF10	P04049	RAF1	S353	P348L	348	Missense	distal	-5	no	8.658	8.908	EPSD	TCGA;ICGC;COSMIC	7.934	Up-regulation
TKL_RAF_RAF_RAF1_ST	Q13118	KLF10	P04049	RAF1	S353	F350C	350	Missense	distal	-3	no	8.658	5.840	EPSD	TCGA	7.934	Loss
TKL_RAF_RAF_RAF1_ST	Q13118	KLF10	P04049	RAF1	S353	P352S	352	Missense	proximal	-1	no	8.658	9.192	EPSD	TCGA;COSMIC	7.934	Up-regulation
TKL_RAF_RAF_RAF1_ST	Q13118	KLF10	P04049	RAF1	S353	P352L	352	Missense	proximal	-1	no	8.658	9.092	EPSD	TCGA;COSMIC	7.934	Up-regulation
TKL_RAF_RAF_RAF1_ST	Q13118	KLF10	P04049	RAF1	S353	V357I	357	Missense	distal	4	no	8.658	8.287	EPSD	TCGA;COSMIC	7.934	Down-regulation
TKL_RAF_RAF_RAF1_ST	Q13118	KLF10	P04049	RAF1	S384	Y380C	380	Missense	distal	-4	no	7.651	8.952	EPSD	TCGA;COSMIC	7.934	Gain
TKL_RAF_RAF_RAF1_ST	Q13118	KLF10	P04049	RAF1	T394	T392M	392	Missense	proximal	-2	no	8.435	8.482	EPSD	TCGA;COSMIC	7.934	Up-regulation
TKL_RAF_RAF_RAF1_ST	Q13118	KLF10	P04049	RAF1	T424	R418K	418	Missense	distal	-6	no	7.771	7.963	EPSD	TCGA;COSMIC	7.934	Gain
TKL_RAF_RAF_RAF1_ST	Q92934	BAD	P04049	RAF1	S75	S71I	71	Missense	distal	-4	no	17.199	13.504	PhosphoSitePlus;EPSD	TCGA;ICGC;COSMIC	7.934	Down-regulation
TKL_RAF_RAF_RAF1_ST	Q92934	BAD	P04049	RAF1	S99	A100T	100	Missense	proximal	1	no	13.786	14.250	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	7.934	Up-regulation
TKL_RAF_RAF_RAF1_ST	Q92934	BAD	P04049	RAF1	S118	M117I	117	Missense	proximal	-1	no	14.641	14.355	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	7.934	Down-regulation
TKL_RAF_RAF_RAF1_ST	Q92934	BAD	P04049	RAF1	S134	R131H	131	Missense	distal	-3	no	8.211	0.605	EPSD	TCGA;ICGC;COSMIC	7.934	Loss
TKL_RAF_RAF_RAF1_ST	Q92934	BAD	P04049	RAF1	S134	G136D	136	Missense	proximal	2	no	8.211	7.769	EPSD	TCGA;ICGC;COSMIC	7.934	Loss
TKL_RAF_RAF_RAF1_ST	Q92934	BAD	P04049	RAF1	S134	S134I	134	Missense	central	0	yes	8.211	0.000	EPSD	TCGA	7.934	Loss
TKL_RAF_RAF_RAF1_ST	Q02750	MAP2K1	P04049	RAF1	S218	V224M	224	Missense	distal	6	no	14.805	14.807	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	7.934	Up-regulation
TKL_RAF_RAF_RAF1_ST	Q02750	MAP2K1	P04049	RAF1	S222	V224M	224	Missense	proximal	2	no	13.804	13.284	PhosphoSitePlus;EPSD	TCGA;ICGC;COSMIC	7.934	Down-regulation
TKL_RAF_RAF_RAF1_ST	Q02750	MAP2K1	P04049	RAF1	S222	R227K	227	Missense	distal	5	no	13.804	13.665	PhosphoSitePlus;EPSD	TCGA;ICGC;COSMIC	7.934	Down-regulation
TKL_RAF_RAF_RAF1_ST	Q02750	MAP2K1	P04049	RAF1	T292	G294R	294	Missense	proximal	2	no	9.208	9.234	EPSD	TCGA;ICGC;COSMIC	7.934	Up-regulation
TKL_RAF_RAF_RAF1_ST	Q02750	MAP2K1	P04049	RAF1	T292	G294V	294	Missense	proximal	2	no	9.208	10.212	EPSD	TCGA;ICGC;COSMIC	7.934	Up-regulation
TKL_RAF_RAF_RAF1_ST	Q02750	MAP2K1	P04049	RAF1	T292	G294E	294	Missense	proximal	2	no	9.208	9.432	EPSD	TCGA;ICGC;COSMIC	7.934	Up-regulation
TKL_RAF_RAF_RAF1_ST	Q02750	MAP2K1	P04049	RAF1	T292	P290S	290	Missense	proximal	-2	no	9.208	9.303	EPSD	TCGA;ICGC	7.934	Up-regulation
TKL_RAF_RAF_RAF1_ST	Q05639	EEF1A2	P04049	RAF1	S21	G25S	25	Missense	distal	4	no	12.629	12.872	PhosphoSitePlus	TCGA;ICGC	7.934	Up-regulation
TKL_RAF_RAF_RAF1_ST	Q05639	EEF1A2	P04049	RAF1	S76	G70S	70	Missense	distal	-6	no	8.505	8.309	EPSD	TCGA;ICGC;COSMIC	7.934	Down-regulation
TKL_RAF_RAF_RAF1_ST	Q05639	EEF1A2	P04049	RAF1	S76	F80L	80	Missense	distal	4	no	8.505	9.428	EPSD	TCGA;ICGC;COSMIC	7.934	Up-regulation
TKL_RAF_RAF_RAF1_ST	Q05639	EEF1A2	P04049	RAF1	S76	D74N	74	Missense	proximal	-2	no	8.505	8.600	EPSD	TCGA;ICGC	7.934	Up-regulation
TKL_RAF_RAF_RAF1_ST	Q05639	EEF1A2	P04049	RAF1	T279	A281T	281	Missense	proximal	2	no	10.255	9.465	EPSD	TCGA;ICGC;COSMIC	7.934	Down-regulation
TKL_RAF_RAF_RAF1_ST	Q05639	EEF1A2	P04049	RAF1	T279	M276I	276	Missense	distal	-3	no	10.255	10.110	EPSD	TCGA;ICGC;COSMIC	7.934	Down-regulation
TKL_RAF_RAF_RAF1_ST	Q05639	EEF1A2	P04049	RAF1	S358	V360A	360	Missense	proximal	2	no	9.098	9.363	EPSD	TCGA;ICGC;COSMIC	7.934	Up-regulation
TKL_RAF_RAF_RAF1_ST	Q05639	EEF1A2	P04049	RAF1	S358	P359L	359	Missense	proximal	1	no	9.098	8.729	EPSD	TCGA;ICGC;COSMIC	7.934	Down-regulation
TKL_RAF_RAF_RAF1_ST	Q05639	EEF1A2	P04049	RAF1	S358	A355T	355	Missense	distal	-3	no	9.098	7.873	EPSD	TCGA;ICGC;COSMIC	7.934	Loss
TKL_RAF_RAF_RAF1_ST	Q05639	EEF1A2	P04049	RAF1	T432	T432M	432	Missense	central	0	yes	10.550	0.000	EPSD	TCGA;ICGC;COSMIC	7.934	Loss
TKL_RAF_RAF_RAF1_ST	P01106	MYC	P04049	RAF1	S159	S161L	161	Missense	proximal	2	no	8.148	8.210	EPSD	TCGA;ICGC;COSMIC	7.934	Up-regulation
TKL_RAF_RAF_RAF1_ST	P01106	MYC	P04049	RAF1	S202	S207L	207	Missense	distal	5	no	9.051	9.427	EPSD	TCGA;ICGC;COSMIC	7.934	Up-regulation
TKL_RAF_RAF_RAF1_ST	P01106	MYC	P04049	RAF1	T343	K341R	341	Missense	proximal	-2	no	10.530	10.533	EPSD	TCGA;ICGC;COSMIC	7.934	Up-regulation
TKL_RAF_RAF_RAF1_ST	O14974	PPP1R12A	P04049	RAF1	S357	S354I	354	Missense	distal	-3	no	5.386	8.098	EPSD	TCGA;ICGC;COSMIC	7.934	Gain
TKL_RAF_RAF_RAF1_ST	O14974	PPP1R12A	P04049	RAF1	S472	R475K	475	Missense	distal	3	no	8.586	8.373	EPSD	TCGA;ICGC;COSMIC	7.934	Down-regulation
TKL_RAF_RAF_RAF1_ST	O14974	PPP1R12A	P04049	RAF1	S520	R523Q	523	Missense	distal	3	no	8.204	7.138	EPSD	TCGA;GDSC	7.934	Loss
TKL_RAF_RAF_RAF1_ST	O14974	PPP1R12A	P04049	RAF1	S525	R523Q	523	Missense	proximal	-2	no	10.526	10.616	EPSD	TCGA;GDSC	7.934	Up-regulation
TKL_RAF_RAF_RAF1_ST	O14974	PPP1R12A	P04049	RAF1	T696	R694T	694	Missense	proximal	-2	no	13.629	13.633	PhosphoSitePlus	TCGA;COSMIC	7.934	Up-regulation
TKL_RAF_RAF_RAF1_ST	O14974	PPP1R12A	P04049	RAF1	T696	T700S	700	Missense	distal	4	no	13.629	14.627	PhosphoSitePlus	TCGA;ICGC;COSMIC	7.934	Up-regulation
TKL_RAF_RAF_RAF1_ST	O14974	PPP1R12A	P04049	RAF1	T702	E706Q	706	Missense	distal	4	no	8.040	8.650	EPSD	TCGA;ICGC;COSMIC	7.934	Up-regulation
TKL_RAF_RAF_RAF1_ST	O14974	PPP1R12A	P04049	RAF1	T702	T700S	700	Missense	proximal	-2	no	8.040	8.070	EPSD	TCGA;ICGC;COSMIC	7.934	Up-regulation
TKL_RAF_RAF_RAF1_ST	O14974	PPP1R12A	P04049	RAF1	S759	R760K	760	Missense	proximal	1	no	9.199	9.185	EPSD	TCGA;ICGC;COSMIC	7.934	Down-regulation
TKL_RAF_RAF_RAF1_ST	O14974	PPP1R12A	P04049	RAF1	S759	T761M	761	Missense	proximal	2	no	9.199	9.203	EPSD	TCGA;ICGC;COSMIC	7.934	Up-regulation
TKL_RAF_RAF_RAF1_ST	O14974	PPP1R12A	P04049	RAF1	T892	E891K	891	Missense	proximal	-1	no	11.068	11.129	EPSD	TCGA;ICGC;COSMIC	7.934	Up-regulation
TKL_RAF_RAF_RAF1_ST	O14974	PPP1R12A	P04049	RAF1	T892	S894Y	894	Missense	proximal	2	no	11.068	11.409	EPSD	TCGA;COSMIC	7.934	Up-regulation
TKL_RAF_RAF_RAF1_ST	O14974	PPP1R12A	P04049	RAF1	S910	S903A	903	Missense	distal	-7	no	10.625	10.538	EPSD	TCGA;ICGC;COSMIC	7.934	Down-regulation
TKL_RAF_RAF_RAF1_ST	O14974	PPP1R12A	P04049	RAF1	S910	R907C	907	Missense	distal	-3	no	10.625	3.632	EPSD	TCGA;ICGC;COSMIC	7.934	Loss
CAMK_MAPKAPK_MK2_MAPKAPK2_ST	Q8N5C8	TAB3	P49137	MAPKAPK2	S103	P109S	109	Missense	distal	6	no	12.834	12.851	EPSD	TCGA;ICGC;COSMIC	11.681	Up-regulation
CAMK_MAPKAPK_MK2_MAPKAPK2_ST	Q8N5C8	TAB3	P49137	MAPKAPK2	S103	Q110R	110	Missense	distal	7	no	12.834	13.197	EPSD	TCGA;ICGC	11.681	Up-regulation
CAMK_MAPKAPK_MK2_MAPKAPK2_ST	Q8N5C8	TAB3	P49137	MAPKAPK2	S347	G344E	344	Missense	distal	-3	no	7.667	13.031	EPSD	TCGA;ICGC;COSMIC	11.681	Gain
CAMK_MAPKAPK_MK2_MAPKAPK2_ST	Q8N5C8	TAB3	P49137	MAPKAPK2	S356	T354S	354	Missense	proximal	-2	no	12.174	13.928	EPSD	TCGA;ICGC;COSMIC	11.681	Up-regulation
CAMK_MAPKAPK_MK2_MAPKAPK2_ST	Q8N5C8	TAB3	P49137	MAPKAPK2	S356	A349V	349	Missense	distal	-7	no	12.174	12.218	EPSD	TCGA;ICGC;COSMIC	11.681	Up-regulation
CAMK_MAPKAPK_MK2_MAPKAPK2_ST	Q8N5C8	TAB3	P49137	MAPKAPK2	S356	G361C	361	Missense	distal	5	no	12.174	12.129	EPSD	TCGA;ICGC;COSMIC;CCLE	11.681	Down-regulation
CAMK_MAPKAPK_MK2_MAPKAPK2_ST	Q8N5C8	TAB3	P49137	MAPKAPK2	S356	M363I	363	Missense	distal	7	no	12.174	12.056	EPSD	TCGA;ICGC	11.681	Down-regulation
CAMK_MAPKAPK_MK2_MAPKAPK2_ST	Q8N5C8	TAB3	P49137	MAPKAPK2	S357	T354S	354	Missense	distal	-3	no	12.050	11.596	EPSD	TCGA;ICGC;COSMIC	11.681	Loss
CAMK_MAPKAPK_MK2_MAPKAPK2_ST	Q8N5C8	TAB3	P49137	MAPKAPK2	S357	G361C	361	Missense	distal	4	no	12.050	12.062	EPSD	TCGA;ICGC;COSMIC;CCLE	11.681	Up-regulation
CAMK_MAPKAPK_MK2_MAPKAPK2_ST	Q8N5C8	TAB3	P49137	MAPKAPK2	S357	M363I	363	Missense	distal	6	no	12.050	12.042	EPSD	TCGA;ICGC	11.681	Down-regulation
CAMK_MAPKAPK_MK2_MAPKAPK2_ST	Q8N5C8	TAB3	P49137	MAPKAPK2	S359	T354S	354	Missense	distal	-5	no	11.696	11.777	EPSD	TCGA;ICGC;COSMIC	11.681	Up-regulation
CAMK_MAPKAPK_MK2_MAPKAPK2_ST	Q8N5C8	TAB3	P49137	MAPKAPK2	S359	G361C	361	Missense	proximal	2	no	11.696	11.730	EPSD	TCGA;ICGC;COSMIC;CCLE	11.681	Up-regulation
CAMK_MAPKAPK_MK2_MAPKAPK2_ST	Q8N5C8	TAB3	P49137	MAPKAPK2	S359	M363I	363	Missense	distal	4	no	11.696	11.603	EPSD	TCGA;ICGC	11.681	Loss
CAMK_MAPKAPK_MK2_MAPKAPK2_ST	Q8N5C8	TAB3	P49137	MAPKAPK2	S385	R382K	382	Missense	distal	-3	no	18.895	13.771	EPSD	TCGA;ICGC;COSMIC	11.681	Down-regulation
CAMK_MAPKAPK_MK2_MAPKAPK2_ST	Q8N5C8	TAB3	P49137	MAPKAPK2	S409	S411L	411	Missense	proximal	2	no	15.751	15.336	EPSD	TCGA;ICGC;COSMIC	11.681	Down-regulation
CAMK_MAPKAPK_MK2_MAPKAPK2_ST	Q8N5C8	TAB3	P49137	MAPKAPK2	S409	T404M	404	Missense	distal	-5	no	15.751	15.571	EPSD	TCGA;ICGC;COSMIC	11.681	Down-regulation
CAMK_MAPKAPK_MK2_MAPKAPK2_ST	Q8N5C8	TAB3	P49137	MAPKAPK2	S409	G413W	413	Missense	distal	4	no	15.751	15.765	EPSD	TCGA;ICGC;COSMIC	11.681	Up-regulation
CAMK_MAPKAPK_MK2_MAPKAPK2_ST	Q8N5C8	TAB3	P49137	MAPKAPK2	S409	P410L	410	Missense	proximal	1	no	15.751	15.842	EPSD	TCGA;ICGC;COSMIC	11.681	Up-regulation
CAMK_MAPKAPK_MK2_MAPKAPK2_ST	Q8N5C8	TAB3	P49137	MAPKAPK2	S409	G413V	413	Missense	distal	4	no	15.751	15.812	EPSD	TCGA;ICGC;COSMIC	11.681	Up-regulation
CAMK_MAPKAPK_MK2_MAPKAPK2_ST	Q8N5C8	TAB3	P49137	MAPKAPK2	S409	S415C	415	Missense	distal	6	no	15.751	15.723	EPSD	TCGA;ICGC;COSMIC	11.681	Down-regulation
CAMK_MAPKAPK_MK2_MAPKAPK2_ST	Q8N5C8	TAB3	P49137	MAPKAPK2	S409	S409F	409	Missense	central	0	yes	15.751	0.000	EPSD	TCGA;ICGC;COSMIC	11.681	Loss
CAMK_MAPKAPK_MK2_MAPKAPK2_ST	Q8N5C8	TAB3	P49137	MAPKAPK2	S411	S411L	411	Missense	central	0	yes	12.529	0.000	EPSD	TCGA;ICGC;COSMIC	11.681	Loss
CAMK_MAPKAPK_MK2_MAPKAPK2_ST	Q8N5C8	TAB3	P49137	MAPKAPK2	S411	T404M	404	Missense	distal	-7	no	12.529	12.589	EPSD	TCGA;ICGC;COSMIC	11.681	Up-regulation
CAMK_MAPKAPK_MK2_MAPKAPK2_ST	Q8N5C8	TAB3	P49137	MAPKAPK2	S411	G413W	413	Missense	proximal	2	no	12.529	12.548	EPSD	TCGA;ICGC;COSMIC	11.681	Up-regulation
CAMK_MAPKAPK_MK2_MAPKAPK2_ST	Q8N5C8	TAB3	P49137	MAPKAPK2	S411	P410L	410	Missense	proximal	-1	no	12.529	12.528	EPSD	TCGA;ICGC;COSMIC	11.681	Down-regulation
CAMK_MAPKAPK_MK2_MAPKAPK2_ST	Q8N5C8	TAB3	P49137	MAPKAPK2	S411	G413V	413	Missense	proximal	2	no	12.529	12.629	EPSD	TCGA;ICGC;COSMIC	11.681	Up-regulation
CAMK_MAPKAPK_MK2_MAPKAPK2_ST	Q8N5C8	TAB3	P49137	MAPKAPK2	S411	S415C	415	Missense	distal	4	no	12.529	12.352	EPSD	TCGA;ICGC;COSMIC	11.681	Down-regulation
CAMK_MAPKAPK_MK2_MAPKAPK2_ST	Q8N5C8	TAB3	P49137	MAPKAPK2	S411	S409F	409	Missense	proximal	-2	no	12.529	7.103	EPSD	TCGA;ICGC;COSMIC	11.681	Loss
CAMK_MAPKAPK_MK2_MAPKAPK2_ST	Q8N5C8	TAB3	P49137	MAPKAPK2	S415	S411L	411	Missense	distal	-4	no	17.875	18.079	EPSD	TCGA;ICGC;COSMIC	11.681	Up-regulation
CAMK_MAPKAPK_MK2_MAPKAPK2_ST	Q8N5C8	TAB3	P49137	MAPKAPK2	S415	G413W	413	Missense	proximal	-2	no	17.875	17.195	EPSD	TCGA;ICGC;COSMIC	11.681	Down-regulation
CAMK_MAPKAPK_MK2_MAPKAPK2_ST	Q8N5C8	TAB3	P49137	MAPKAPK2	S415	P410L	410	Missense	distal	-5	no	17.875	18.380	EPSD	TCGA;ICGC;COSMIC	11.681	Up-regulation
CAMK_MAPKAPK_MK2_MAPKAPK2_ST	Q8N5C8	TAB3	P49137	MAPKAPK2	S415	G413V	413	Missense	proximal	-2	no	17.875	17.416	EPSD	TCGA;ICGC;COSMIC	11.681	Down-regulation
CAMK_MAPKAPK_MK2_MAPKAPK2_ST	Q8N5C8	TAB3	P49137	MAPKAPK2	S415	S415C	415	Missense	central	0	yes	17.875	0.000	EPSD	TCGA;ICGC;COSMIC	11.681	Loss
CAMK_MAPKAPK_MK2_MAPKAPK2_ST	Q8N5C8	TAB3	P49137	MAPKAPK2	S415	P421T	421	Missense	distal	6	no	17.875	17.889	EPSD	TCGA;ICGC	11.681	Up-regulation
CAMK_MAPKAPK_MK2_MAPKAPK2_ST	Q8N5C8	TAB3	P49137	MAPKAPK2	S415	S409F	409	Missense	distal	-6	no	17.875	17.983	EPSD	TCGA;ICGC;COSMIC	11.681	Up-regulation
CAMK_MAPKAPK_MK2_MAPKAPK2_ST	Q8N5C8	TAB3	P49137	MAPKAPK2	S504	S498R	498	Missense	distal	-6	no	11.715	11.727	EPSD	TCGA;ICGC;COSMIC	11.681	Up-regulation
CAMK_MAPKAPK_MK2_MAPKAPK2_ST	Q8N5C8	TAB3	P49137	MAPKAPK2	S563	S563C	563	Missense	central	0	yes	17.200	0.000	EPSD	TCGA;COSMIC	11.681	Loss
CAMK_MAPKAPK_MK2_MAPKAPK2_ST	Q8N5C8	TAB3	P49137	MAPKAPK2	S563	T570M	570	Missense	distal	7	no	17.200	16.752	EPSD	TCGA;COSMIC	11.681	Down-regulation
CAMK_MAPKAPK_MK2_MAPKAPK2_ST	Q8N5C8	TAB3	P49137	MAPKAPK2	S563	A567V	567	Missense	distal	4	no	17.200	17.049	EPSD	TCGA;COSMIC	11.681	Down-regulation
CAMK_MAPKAPK_MK2_MAPKAPK2_ST	Q8N5C8	TAB3	P49137	MAPKAPK2	S563	P569S	569	Missense	distal	6	no	17.200	17.217	EPSD	TCGA;COSMIC	11.681	Up-regulation
CAMK_MAPKAPK_MK2_MAPKAPK2_ST	Q8N5C8	TAB3	P49137	MAPKAPK2	S563	P569L	569	Missense	distal	6	no	17.200	17.196	EPSD	TCGA;COSMIC;GDSC;CCLE	11.681	Down-regulation
CAMK_MAPKAPK_MK2_MAPKAPK2_ST	Q8N5C8	TAB3	P49137	MAPKAPK2	S563	R560I	560	Missense	distal	-3	no	17.200	11.911	EPSD	TCGA;COSMIC	11.681	Down-regulation
CAMK_MAPKAPK_MK2_MAPKAPK2_ST	Q8N5C8	TAB3	P49137	MAPKAPK2	S645	E638Q	638	Missense	distal	-7	no	16.864	16.915	EPSD	TCGA;ICGC;COSMIC	11.681	Up-regulation
CAMK_MAPKAPK_MK2_MAPKAPK2_ST	Q8N5C8	TAB3	P49137	MAPKAPK2	S645	A652T	652	Missense	distal	7	no	16.864	16.965	EPSD	TCGA;ICGC;COSMIC	11.681	Up-regulation
CAMK_MAPKAPK_MK2_MAPKAPK2_ST	Q8N5C8	TAB3	P49137	MAPKAPK2	S645	R642Q	642	Missense	distal	-3	no	16.864	11.100	EPSD	TCGA;ICGC;COSMIC	11.681	Loss
CAMK_MAPKAPK_MK2_MAPKAPK2_ST	Q8N5C8	TAB3	P49137	MAPKAPK2	S645	A641T	641	Missense	distal	-4	no	16.864	16.738	EPSD	TCGA;ICGC;COSMIC	11.681	Down-regulation
CAMK_MAPKAPK_MK2_MAPKAPK2_ST	Q8N5C8	TAB3	P49137	MAPKAPK2	S669	T670S	670	Missense	proximal	1	no	17.529	17.383	EPSD	TCGA;ICGC;COSMIC	11.681	Down-regulation
CAMK_MAPKAPK_MK2_MAPKAPK2_ST	Q8N5C8	TAB3	P49137	MAPKAPK2	S669	R674Q	674	Missense	distal	5	no	17.529	17.748	EPSD	TCGA;ICGC;COSMIC;GDSC;CCLE	11.681	Up-regulation
CAMK_MAPKAPK_MK2_MAPKAPK2_ST	Q8N5C8	TAB3	P49137	MAPKAPK2	S669	R666Q	666	Missense	distal	-3	no	17.529	11.765	EPSD	TCGA;ICGC;COSMIC	11.681	Down-regulation
CAMK_MAPKAPK_MK2_MAPKAPK2_ST	Q8N5C8	TAB3	P49137	MAPKAPK2	S672	T670S	670	Missense	proximal	-2	no	11.605	13.359	EPSD	TCGA;ICGC;COSMIC	11.681	Gain
CAMK_MAPKAPK_MK2_MAPKAPK2_ST	P30305	CDC25B	P49137	MAPKAPK2	S91	R92Q	92	Missense	proximal	1	no	13.750	13.297	EPSD	TCGA;COSMIC	11.681	Down-regulation
CAMK_MAPKAPK_MK2_MAPKAPK2_ST	P30305	CDC25B	P49137	MAPKAPK2	S91	S89Y	89	Missense	proximal	-2	no	13.750	8.879	EPSD	TCGA;COSMIC	11.681	Loss
CAMK_MAPKAPK_MK2_MAPKAPK2_ST	P30305	CDC25B	P49137	MAPKAPK2	S91	E96K	96	Missense	distal	5	no	13.750	13.964	EPSD	TCGA;COSMIC	11.681	Up-regulation
CAMK_MAPKAPK_MK2_MAPKAPK2_ST	P30305	CDC25B	P49137	MAPKAPK2	S91	R84H	84	Missense	distal	-7	no	13.750	13.841	EPSD	TCGA;COSMIC	11.681	Up-regulation
CAMK_MAPKAPK_MK2_MAPKAPK2_ST	P30305	CDC25B	P49137	MAPKAPK2	S117	G110C	110	Missense	distal	-7	no	13.328	13.315	EPSD	TCGA;ICGC;COSMIC	11.681	Down-regulation
CAMK_MAPKAPK_MK2_MAPKAPK2_ST	P30305	CDC25B	P49137	MAPKAPK2	S117	G110D	110	Missense	distal	-7	no	13.328	13.310	EPSD	TCGA;COSMIC	11.681	Down-regulation
CAMK_MAPKAPK_MK2_MAPKAPK2_ST	P30305	CDC25B	P49137	MAPKAPK2	S117	S115F	115	Missense	proximal	-2	no	13.328	7.902	EPSD	TCGA;COSMIC	11.681	Loss
CAMK_MAPKAPK_MK2_MAPKAPK2_ST	P30305	CDC25B	P49137	MAPKAPK2	S151	P153L	153	Missense	proximal	2	no	12.970	12.748	EPSD	TCGA;ICGC;COSMIC	11.681	Down-regulation
CAMK_MAPKAPK_MK2_MAPKAPK2_ST	P30305	CDC25B	P49137	MAPKAPK2	S151	R148H	148	Missense	distal	-3	no	12.970	8.211	EPSD	TCGA;ICGC	11.681	Loss
CAMK_MAPKAPK_MK2_MAPKAPK2_ST	P30305	CDC25B	P49137	MAPKAPK2	T167	S160I	160	Missense	distal	-7	no	12.481	12.513	EPSD	TCGA	11.681	Up-regulation
CAMK_MAPKAPK_MK2_MAPKAPK2_ST	P30305	CDC25B	P49137	MAPKAPK2	T167	S160C	160	Missense	distal	-7	no	12.481	12.526	EPSD	TCGA;COSMIC	11.681	Up-regulation
CAMK_MAPKAPK_MK2_MAPKAPK2_ST	P30305	CDC25B	P49137	MAPKAPK2	T167	V162M	162	Missense	distal	-5	no	12.481	12.033	EPSD	TCGA;ICGC;COSMIC	11.681	Down-regulation
CAMK_MAPKAPK_MK2_MAPKAPK2_ST	P30305	CDC25B	P49137	MAPKAPK2	T167	R164Q	164	Missense	distal	-3	no	12.481	6.718	EPSD	TCGA	11.681	Loss
CAMK_MAPKAPK_MK2_MAPKAPK2_ST	P30305	CDC25B	P49137	MAPKAPK2	S169	V162M	162	Missense	distal	-7	no	12.723	12.718	PhosphoSitePlus;EPSD	TCGA;ICGC;COSMIC	11.681	Down-regulation
CAMK_MAPKAPK_MK2_MAPKAPK2_ST	P30305	CDC25B	P49137	MAPKAPK2	S169	R164Q	164	Missense	distal	-5	no	12.723	12.005	PhosphoSitePlus;EPSD	TCGA	11.681	Down-regulation
CAMK_MAPKAPK_MK2_MAPKAPK2_ST	P30305	CDC25B	P49137	MAPKAPK2	S229	A225V	225	Missense	distal	-4	no	12.727	12.806	EPSD	TCGA;ICGC;COSMIC	11.681	Up-regulation
CAMK_MAPKAPK_MK2_MAPKAPK2_ST	P30305	CDC25B	P49137	MAPKAPK2	S229	Q226H	226	Missense	distal	-3	no	12.727	13.731	EPSD	TCGA;ICGC;COSMIC	11.681	Up-regulation
CAMK_MAPKAPK_MK2_MAPKAPK2_ST	P30305	CDC25B	P49137	MAPKAPK2	S230	A225V	225	Missense	distal	-5	no	16.350	17.021	EPSD	TCGA;ICGC;COSMIC	11.681	Up-regulation
CAMK_MAPKAPK_MK2_MAPKAPK2_ST	P30305	CDC25B	P49137	MAPKAPK2	S230	Q226H	226	Missense	distal	-4	no	16.350	16.400	EPSD	TCGA;ICGC;COSMIC	11.681	Up-regulation
CAMK_MAPKAPK_MK2_MAPKAPK2_ST	P30305	CDC25B	P49137	MAPKAPK2	S230	L237I	237	Missense	distal	7	no	16.350	16.443	EPSD	TCGA	11.681	Up-regulation
CAMK_MAPKAPK_MK2_MAPKAPK2_ST	P30305	CDC25B	P49137	MAPKAPK2	S323	R317Q	317	Missense	distal	-6	no	19.707	19.761	EPSD;PhosphoSitePlus	TCGA;COSMIC	11.681	Up-regulation
CAMK_MAPKAPK_MK2_MAPKAPK2_ST	P30305	CDC25B	P49137	MAPKAPK2	S353	E358K	358	Missense	distal	5	no	16.982	17.196	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	11.681	Up-regulation
CAMK_MAPKAPK_MK2_MAPKAPK2_ST	P30305	CDC25B	P49137	MAPKAPK2	S353	R352W	352	Missense	proximal	-1	no	16.982	17.000	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	11.681	Up-regulation
CAMK_MAPKAPK_MK2_MAPKAPK2_ST	P30305	CDC25B	P49137	MAPKAPK2	T355	E358K	358	Missense	distal	3	no	15.395	15.267	EPSD	TCGA;ICGC;COSMIC	11.681	Down-regulation
CAMK_MAPKAPK_MK2_MAPKAPK2_ST	P30305	CDC25B	P49137	MAPKAPK2	T355	R352W	352	Missense	distal	-3	no	15.395	6.816	EPSD	TCGA;ICGC;COSMIC	11.681	Loss
CAMK_MAPKAPK_MK2_MAPKAPK2_ST	P30305	CDC25B	P49137	MAPKAPK2	S375	E380Q	380	Missense	distal	5	no	19.277	19.423	EPSD;PhosphoSitePlus	TCGA;COSMIC	11.681	Up-regulation
CAMK_MAPKAPK_MK2_MAPKAPK2_ST	P30305	CDC25B	P49137	MAPKAPK2	S375	S373T	373	Missense	proximal	-2	no	19.277	17.522	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	11.681	Down-regulation
CAMK_MAPKAPK_MK2_MAPKAPK2_ST	P30305	CDC25B	P49137	MAPKAPK2	S375	R369H	369	Missense	distal	-6	no	19.277	19.341	EPSD;PhosphoSitePlus	TCGA;COSMIC	11.681	Up-regulation
CAMK_MAPKAPK_MK2_MAPKAPK2_ST	P30305	CDC25B	P49137	MAPKAPK2	T561	R568W	568	Missense	distal	7	no	12.938	12.665	EPSD	TCGA;COSMIC	11.681	Down-regulation
CAMK_MAPKAPK_MK2_MAPKAPK2_ST	P30305	CDC25B	P49137	MAPKAPK2	T561	R562H	562	Missense	proximal	1	no	12.938	12.549	EPSD	TCGA;COSMIC;CCLE	11.681	Down-regulation
CAMK_MAPKAPK_MK2_MAPKAPK2_ST	P30305	CDC25B	P49137	MAPKAPK2	S563	R568W	568	Missense	distal	5	no	12.463	12.682	EPSD	TCGA;COSMIC	11.681	Up-regulation
CAMK_MAPKAPK_MK2_MAPKAPK2_ST	P30305	CDC25B	P49137	MAPKAPK2	S563	R562H	562	Missense	proximal	-1	no	12.463	12.486	EPSD	TCGA;COSMIC;CCLE	11.681	Up-regulation
CAMK_MAPKAPK_MK2_MAPKAPK2_ST	Q13151	HNRNPA0	P49137	MAPKAPK2	S84	S88L	88	Missense	distal	4	no	18.815	18.663	PhosphoSitePlus	TCGA;ICGC;COSMIC	11.681	Down-regulation
CAMK_MAPKAPK_MK2_MAPKAPK2_ST	Q13151	HNRNPA0	P49137	MAPKAPK2	S88	S88L	88	Missense	central	0	yes	15.347	0.000	EPSD	TCGA;ICGC;COSMIC	11.681	Loss
CAMK_MAPKAPK_MK2_MAPKAPK2_ST	P17302	GJA1	P49137	MAPKAPK2	S251	D245N	245	Missense	distal	-6	no	12.263	12.271	EPSD	TCGA	11.681	Up-regulation
CAMK_MAPKAPK_MK2_MAPKAPK2_ST	P17302	GJA1	P49137	MAPKAPK2	S296	R299H	299	Missense	distal	3	no	16.244	16.107	EPSD	TCGA;COSMIC	11.681	Down-regulation
CAMK_MAPKAPK_MK2_MAPKAPK2_ST	P17302	GJA1	P49137	MAPKAPK2	S296	R293K	293	Missense	distal	-3	no	16.244	11.120	EPSD	TCGA;ICGC;COSMIC	11.681	Loss
CAMK_MAPKAPK_MK2_MAPKAPK2_ST	P17302	GJA1	P49137	MAPKAPK2	S296	C298S	298	Missense	proximal	2	no	16.244	16.644	EPSD	TCGA;ICGC;COSMIC	11.681	Up-regulation
CAMK_MAPKAPK_MK2_MAPKAPK2_ST	P17302	GJA1	P49137	MAPKAPK2	S296	S296F	296	Missense	central	0	yes	16.244	0.000	EPSD	TCGA;ICGC;COSMIC	11.681	Loss
CAMK_MAPKAPK_MK2_MAPKAPK2_ST	P17302	GJA1	P49137	MAPKAPK2	S296	S296Y	296	Missense	central	0	yes	16.244	0.000	EPSD	TCGA;ICGC	11.681	Loss
CAMK_MAPKAPK_MK2_MAPKAPK2_ST	P17302	GJA1	P49137	MAPKAPK2	S330	S330F	330	Missense	central	0	yes	12.334	0.000	EPSD	TCGA;ICGC;COSMIC	11.681	Loss
CAMK_MAPKAPK_MK2_MAPKAPK2_ST	P17302	GJA1	P49137	MAPKAPK2	S330	A332T	332	Missense	proximal	2	no	12.334	12.387	EPSD	TCGA;ICGC;COSMIC	11.681	Up-regulation
CAMK_MAPKAPK_MK2_MAPKAPK2_ST	P17302	GJA1	P49137	MAPKAPK2	S330	G324E	324	Missense	distal	-6	no	12.334	12.256	EPSD	TCGA;ICGC;COSMIC	11.681	Down-regulation
CAMK_MAPKAPK_MK2_MAPKAPK2_ST	P17302	GJA1	P49137	MAPKAPK2	S365	V359L	359	Missense	distal	-6	no	16.040	16.027	EPSD	TCGA;ICGC;COSMIC	11.681	Down-regulation
CAMK_MAPKAPK_MK2_MAPKAPK2_ST	P17302	GJA1	P49137	MAPKAPK2	S365	S369N	369	Missense	distal	4	no	16.040	15.846	EPSD	TCGA;ICGC;COSMIC	11.681	Down-regulation
CAMK_MAPKAPK_MK2_MAPKAPK2_ST	P17302	GJA1	P49137	MAPKAPK2	S369	S369N	369	Missense	central	0	yes	17.238	0.000	EPSD	TCGA;ICGC;COSMIC	11.681	Loss
CAMK_MAPKAPK_MK2_MAPKAPK2_ST	P17302	GJA1	P49137	MAPKAPK2	S373	S369N	369	Missense	distal	-4	no	17.666	17.888	EPSD	TCGA;ICGC;COSMIC	11.681	Up-regulation
CAMK_MAPKAPK_MK2_MAPKAPK2_ST	P04792	HSPB1	P49137	MAPKAPK2	S15	L10H	10	Missense	distal	-5	no	16.320	15.502	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	11.681	Down-regulation
CAMK_MAPKAPK_MK2_MAPKAPK2_ST	P04792	HSPB1	P49137	MAPKAPK2	S74	L81I	81	Missense	distal	7	no	13.380	13.473	EPSD	TCGA;ICGC;COSMIC	11.681	Up-regulation
CAMK_MAPKAPK_MK2_MAPKAPK2_ST	P04792	HSPB1	P49137	MAPKAPK2	S78	L81I	81	Missense	distal	3	no	17.170	17.177	PhosphoSitePlus;EPSD	TCGA;ICGC;COSMIC	11.681	Up-regulation
CAMK_MAPKAPK_MK2_MAPKAPK2_ST	P04792	HSPB1	P49137	MAPKAPK2	S82	L81I	81	Missense	proximal	-1	no	17.328	17.329	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	11.681	Up-regulation
CAMK_MAPKAPK_MK2_MAPKAPK2_ST	P04792	HSPB1	P49137	MAPKAPK2	S158	E160K	160	Missense	proximal	2	no	13.817	13.519	EPSD	TCGA;ICGC;COSMIC	11.681	Down-regulation
CAMK_MAPKAPK_MK2_MAPKAPK2_ST	P04792	HSPB1	P49137	MAPKAPK2	S158	S158F	158	Missense	central	0	yes	13.817	0.000	EPSD	TCGA	11.681	Loss
CAMK_MAPKAPK_MK2_MAPKAPK2_ST	P53667	LIMK1	P49137	MAPKAPK2	S281	P276L	276	Missense	distal	-5	no	11.360	11.865	EPSD	TCGA;COSMIC;CCLE	11.681	Gain
CAMK_MAPKAPK_MK2_MAPKAPK2_ST	P53667	LIMK1	P49137	MAPKAPK2	S286	P280S	280	Missense	distal	-6	no	13.115	13.114	EPSD	TCGA;COSMIC	11.681	Down-regulation
CAMK_MAPKAPK_MK2_MAPKAPK2_ST	P53667	LIMK1	P49137	MAPKAPK2	S286	R289Q	289	Missense	distal	3	no	13.115	13.019	EPSD	TCGA;COSMIC	11.681	Down-regulation
CAMK_MAPKAPK_MK2_MAPKAPK2_ST	P53667	LIMK1	P49137	MAPKAPK2	S286	R289W	289	Missense	distal	3	no	13.115	13.077	EPSD	TCGA;COSMIC	11.681	Down-regulation
CAMK_MAPKAPK_MK2_MAPKAPK2_ST	P53667	LIMK1	P49137	MAPKAPK2	S298	P303T	303	Missense	distal	5	no	21.044	20.918	EPSD	TCGA;COSMIC	11.681	Down-regulation
CAMK_MAPKAPK_MK2_MAPKAPK2_ST	P53667	LIMK1	P49137	MAPKAPK2	S313	P311S	311	Missense	proximal	-2	no	10.158	13.390	EPSD	TCGA;COSMIC	11.681	Gain
CAMK_MAPKAPK_MK2_MAPKAPK2_ST	P53667	LIMK1	P49137	MAPKAPK2	S323	R329Q	329	Missense	distal	6	no	21.826	21.806	PhosphoSitePlus	TCGA;COSMIC	11.681	Down-regulation
CAMK_MAPKAPK_MK2_MAPKAPK2_ST	P53667	LIMK1	P49137	MAPKAPK2	S323	R329W	329	Missense	distal	6	no	21.826	21.800	PhosphoSitePlus	TCGA;COSMIC	11.681	Down-regulation
CAMK_MAPKAPK_MK2_MAPKAPK2_ST	P53667	LIMK1	P49137	MAPKAPK2	S323	R325H	325	Missense	proximal	2	no	21.826	21.315	PhosphoSitePlus	TCGA	11.681	Down-regulation
CAMK_MAPKAPK_MK2_MAPKAPK2_ST	P53667	LIMK1	P49137	MAPKAPK2	S323	S321C	321	Missense	proximal	-2	no	21.826	18.348	PhosphoSitePlus	TCGA;COSMIC	11.681	Down-regulation
CAMK_MAPKAPK_MK2_MAPKAPK2_ST	P53667	LIMK1	P49137	MAPKAPK2	S323	R320C	320	Missense	distal	-3	no	21.826	13.426	PhosphoSitePlus	TCGA;COSMIC	11.681	Down-regulation
CAMK_MAPKAPK_MK2_MAPKAPK2_ST	P53667	LIMK1	P49137	MAPKAPK2	S637	E636K	636	Missense	proximal	-1	no	13.178	13.188	EPSD	TCGA;COSMIC	11.681	Up-regulation
CAMK_MAPKAPK_MK2_MAPKAPK2_ST	Q96J92	WNK4	P49137	MAPKAPK2	S47	P54S	54	Missense	distal	7	no	16.734	16.617	EPSD	TCGA;ICGC;COSMIC	11.681	Down-regulation
CAMK_MAPKAPK_MK2_MAPKAPK2_ST	Q96J92	WNK4	P49137	MAPKAPK2	S97	S101G	101	Missense	distal	4	no	14.096	13.907	EPSD	TCGA;ICGC;COSMIC	11.681	Down-regulation
CAMK_MAPKAPK_MK2_MAPKAPK2_ST	Q96J92	WNK4	P49137	MAPKAPK2	S575	A574G	574	Missense	proximal	-1	no	15.562	15.575	PhosphoSitePlus	TCGA;ICGC;COSMIC	11.681	Up-regulation
CAMK_MAPKAPK_MK2_MAPKAPK2_ST	Q96J92	WNK4	P49137	MAPKAPK2	S575	L570F	570	Missense	distal	-5	no	15.562	14.864	PhosphoSitePlus	TCGA;ICGC;COSMIC	11.681	Down-regulation
CAMK_MAPKAPK_MK2_MAPKAPK2_ST	Q96J92	WNK4	P49137	MAPKAPK2	S680	R687T	687	Missense	distal	7	no	16.618	16.892	EPSD	TCGA;ICGC;COSMIC	11.681	Up-regulation
CAMK_MAPKAPK_MK2_MAPKAPK2_ST	Q96J92	WNK4	P49137	MAPKAPK2	S682	R687T	687	Missense	distal	5	no	12.775	12.713	EPSD	TCGA;ICGC;COSMIC	11.681	Down-regulation
CAMK_MAPKAPK_MK2_MAPKAPK2_ST	Q96J92	WNK4	P49137	MAPKAPK2	S728	S728L	728	Missense	central	0	yes	11.762	0.000	EPSD	TCGA;ICGC;COSMIC	11.681	Loss
CAMK_MAPKAPK_MK2_MAPKAPK2_ST	Q96J92	WNK4	P49137	MAPKAPK2	S1053	E1052K	1052	Missense	proximal	-1	no	14.462	14.472	EPSD	TCGA;ICGC;COSMIC	11.681	Up-regulation
CAMK_MAPKAPK_MK2_MAPKAPK2_ST	Q96J92	WNK4	P49137	MAPKAPK2	S1190	R1185C	1185	Missense	distal	-5	no	17.327	16.722	EPSD	TCGA;ICGC;COSMIC	11.681	Down-regulation
CAMK_MAPKAPK_MK2_MAPKAPK2_ST	Q96J92	WNK4	P49137	MAPKAPK2	S1201	P1208Q	1208	Missense	distal	7	no	17.888	17.436	EPSD	TCGA;ICGC;COSMIC	11.681	Down-regulation
CAMK_MAPKAPK_MK2_MAPKAPK2_ST	Q96J92	WNK4	P49137	MAPKAPK2	S1217	I1212N	1212	Missense	distal	-5	no	17.773	16.770	EPSD	TCGA;ICGC;COSMIC	11.681	Down-regulation
CAMK_MAPKAPK_MK2_MAPKAPK2_ST	Q96J92	WNK4	P49137	MAPKAPK2	S1219	I1212N	1212	Missense	distal	-7	no	12.359	12.377	EPSD	TCGA;ICGC;COSMIC	11.681	Up-regulation
CAMK_MAPKAPK_MK2_MAPKAPK2_ST	P16220	CREB1	P49137	MAPKAPK2	S98	S103A	103	Missense	distal	5	no	14.856	14.896	EPSD	TCGA;COSMIC	11.681	Up-regulation
CAMK_MAPKAPK_MK2_MAPKAPK2_ST	P16220	CREB1	P49137	MAPKAPK2	S133	L128I	128	Missense	distal	-5	no	17.252	17.064	PhosphoSitePlus	TCGA;COSMIC	11.681	Down-regulation
CAMK_MAPKAPK_MK2_MAPKAPK2_ST	Q6JBY9	RCSD1	P49137	MAPKAPK2	S17	D13E	13	Missense	distal	-4	no	15.435	15.264	EPSD	TCGA;ICGC;COSMIC	11.681	Down-regulation
CAMK_MAPKAPK_MK2_MAPKAPK2_ST	Q6JBY9	RCSD1	P49137	MAPKAPK2	S17	P18S	18	Missense	proximal	1	no	15.435	15.325	EPSD	TCGA;ICGC;COSMIC	11.681	Down-regulation
CAMK_MAPKAPK_MK2_MAPKAPK2_ST	Q6JBY9	RCSD1	P49137	MAPKAPK2	S17	S19L	19	Missense	proximal	2	no	15.435	15.020	EPSD	TCGA;ICGC;COSMIC	11.681	Down-regulation
CAMK_MAPKAPK_MK2_MAPKAPK2_ST	Q6JBY9	RCSD1	P49137	MAPKAPK2	S50	P47L	47	Missense	distal	-3	no	12.794	12.368	EPSD	TCGA;ICGC;COSMIC;GDSC;CCLE	11.681	Down-regulation
CAMK_MAPKAPK_MK2_MAPKAPK2_ST	Q6JBY9	RCSD1	P49137	MAPKAPK2	S105	K107N	107	Missense	proximal	2	no	12.299	12.389	EPSD	TCGA;COSMIC	11.681	Up-regulation
CAMK_MAPKAPK_MK2_MAPKAPK2_ST	Q6JBY9	RCSD1	P49137	MAPKAPK2	S105	A98T	98	Missense	distal	-7	no	12.299	12.278	EPSD	TCGA;ICGC;COSMIC	11.681	Down-regulation
CAMK_MAPKAPK_MK2_MAPKAPK2_ST	Q6JBY9	RCSD1	P49137	MAPKAPK2	S135	S132Y	132	Missense	distal	-3	no	11.197	11.785	EPSD	TCGA;ICGC;COSMIC	11.681	Gain
CAMK_MAPKAPK_MK2_MAPKAPK2_ST	Q6JBY9	RCSD1	P49137	MAPKAPK2	S171	Q178P	178	Missense	distal	7	no	15.142	15.593	EPSD	TCGA;ICGC;COSMIC	11.681	Up-regulation
CAMK_MAPKAPK_MK2_MAPKAPK2_ST	Q6JBY9	RCSD1	P49137	MAPKAPK2	S171	P170T	170	Missense	proximal	-1	no	15.142	15.137	EPSD	TCGA;COSMIC	11.681	Down-regulation
CAMK_MAPKAPK_MK2_MAPKAPK2_ST	Q6JBY9	RCSD1	P49137	MAPKAPK2	S171	R168S	168	Missense	distal	-3	no	15.142	8.812	EPSD	TCGA;ICGC;COSMIC	11.681	Loss
CAMK_MAPKAPK_MK2_MAPKAPK2_ST	Q6JBY9	RCSD1	P49137	MAPKAPK2	S171	R173Q	173	Missense	proximal	2	no	15.142	14.838	EPSD	TCGA;ICGC;COSMIC	11.681	Down-regulation
CAMK_MAPKAPK_MK2_MAPKAPK2_ST	Q6JBY9	RCSD1	P49137	MAPKAPK2	S179	Q178P	178	Missense	proximal	-1	no	19.154	19.140	PhosphoSitePlus;EPSD	TCGA;ICGC;COSMIC	11.681	Down-regulation
CAMK_MAPKAPK_MK2_MAPKAPK2_ST	Q6JBY9	RCSD1	P49137	MAPKAPK2	S179	R173Q	173	Missense	distal	-6	no	19.154	19.208	PhosphoSitePlus;EPSD	TCGA;ICGC;COSMIC	11.681	Up-regulation
CAMK_MAPKAPK_MK2_MAPKAPK2_ST	Q6JBY9	RCSD1	P49137	MAPKAPK2	S242	P243H	243	Missense	proximal	1	no	11.822	11.346	EPSD	TCGA;COSMIC	11.681	Loss
CAMK_MAPKAPK_MK2_MAPKAPK2_ST	Q6JBY9	RCSD1	P49137	MAPKAPK2	S242	R240K	240	Missense	proximal	-2	no	11.822	9.648	EPSD	TCGA;COSMIC	11.681	Loss
CAMK_MAPKAPK_MK2_MAPKAPK2_ST	Q6JBY9	RCSD1	P49137	MAPKAPK2	S242	R240M	240	Missense	proximal	-2	no	11.822	11.963	EPSD	TCGA;COSMIC	11.681	Up-regulation
CAMK_MAPKAPK_MK2_MAPKAPK2_ST	Q6JBY9	RCSD1	P49137	MAPKAPK2	S244	P243H	243	Missense	proximal	-1	no	19.793	19.805	EPSD;PhosphoSitePlus	TCGA;COSMIC	11.681	Up-regulation
CAMK_MAPKAPK_MK2_MAPKAPK2_ST	Q6JBY9	RCSD1	P49137	MAPKAPK2	S244	R240K	240	Missense	distal	-4	no	19.793	20.037	EPSD;PhosphoSitePlus	TCGA;COSMIC	11.681	Up-regulation
CAMK_MAPKAPK_MK2_MAPKAPK2_ST	Q6JBY9	RCSD1	P49137	MAPKAPK2	S244	R240M	240	Missense	distal	-4	no	19.793	19.945	EPSD;PhosphoSitePlus	TCGA;COSMIC	11.681	Up-regulation
CAMK_MAPKAPK_MK2_MAPKAPK2_ST	Q6JBY9	RCSD1	P49137	MAPKAPK2	S298	A305S	305	Missense	distal	7	no	16.417	16.217	EPSD	TCGA;ICGC;COSMIC	11.681	Down-regulation
CAMK_MAPKAPK_MK2_MAPKAPK2_ST	Q6JBY9	RCSD1	P49137	MAPKAPK2	S298	G297E	297	Missense	proximal	-1	no	16.417	16.401	EPSD	TCGA;ICGC;COSMIC	11.681	Down-regulation
CAMK_MAPKAPK_MK2_MAPKAPK2_ST	Q6JBY9	RCSD1	P49137	MAPKAPK2	S298	E293G	293	Missense	distal	-5	no	16.417	15.588	EPSD	TCGA;ICGC	11.681	Down-regulation
CAMK_MAPKAPK_MK2_MAPKAPK2_ST	P63104	YWHAZ	P49137	MAPKAPK2	S190	A195V	195	Missense	distal	5	no	11.589	11.732	EPSD	TCGA;ICGC	11.681	Gain
CAMK_MAPKAPK_MK2_MAPKAPK2_ST	Q9UKV8	AGO2	P49137	MAPKAPK2	S153	E157K	157	Missense	distal	4	no	15.685	15.504	EPSD	TCGA;ICGC;COSMIC	11.681	Down-regulation
CAMK_MAPKAPK_MK2_MAPKAPK2_ST	Q9UKV8	AGO2	P49137	MAPKAPK2	S385	R384Q	384	Missense	proximal	-1	no	12.419	12.443	EPSD	TCGA;ICGC;COSMIC	11.681	Up-regulation
CAMK_MAPKAPK_MK2_MAPKAPK2_ST	Q9UKV8	AGO2	P49137	MAPKAPK2	S385	P392S	392	Missense	distal	7	no	12.419	12.302	EPSD	TCGA;ICGC;COSMIC	11.681	Down-regulation
CAMK_MAPKAPK_MK2_MAPKAPK2_ST	Q9UKV8	AGO2	P49137	MAPKAPK2	S387	R384Q	384	Missense	distal	-3	no	18.966	13.202	PhosphoSitePlus	TCGA;ICGC;COSMIC	11.681	Down-regulation
CAMK_MAPKAPK_MK2_MAPKAPK2_ST	Q9UKV8	AGO2	P49137	MAPKAPK2	S387	V394I	394	Missense	distal	7	no	18.966	18.926	PhosphoSitePlus	TCGA;ICGC;COSMIC	11.681	Down-regulation
CAMK_MAPKAPK_MK2_MAPKAPK2_ST	Q9UKV8	AGO2	P49137	MAPKAPK2	S387	P392S	392	Missense	distal	5	no	18.966	18.883	PhosphoSitePlus	TCGA;ICGC;COSMIC	11.681	Down-regulation
CAMK_MAPKAPK_MK2_MAPKAPK2_ST	Q9UKV8	AGO2	P49137	MAPKAPK2	S798	P802R	802	Missense	distal	4	no	17.334	17.328	EPSD	TCGA;COSMIC	11.681	Down-regulation
CAMK_MAPKAPK_MK2_MAPKAPK2_ST	Q9UKV8	AGO2	P49137	MAPKAPK2	S798	R792C	792	Missense	distal	-6	no	17.334	17.384	EPSD	TCGA;COSMIC	11.681	Up-regulation
CAMK_MAPKAPK_MK2_MAPKAPK2_ST	O95816	BAG2	P49137	MAPKAPK2	S20	D23N	23	Missense	distal	3	no	18.718	18.671	PhosphoSitePlus	TCGA;ICGC;COSMIC	11.681	Down-regulation
CAMK_MAPKAPK_MK2_MAPKAPK2_ST	O95816	BAG2	P49137	MAPKAPK2	S20	S25P	25	Missense	distal	5	no	18.718	18.801	PhosphoSitePlus	TCGA	11.681	Up-regulation
CAMK_MAPKAPK_MK2_MAPKAPK2_ST	O95816	BAG2	P49137	MAPKAPK2	S143	S144C	144	Missense	proximal	1	no	12.085	11.847	EPSD	TCGA;ICGC;COSMIC	11.681	Down-regulation
CAMK_MAPKAPK_MK2_MAPKAPK2_ST	Q9Y580	RBM7	P49137	MAPKAPK2	S113	E118K	118	Missense	distal	5	no	13.214	13.427	EPSD	TCGA;COSMIC	11.681	Up-regulation
CAMK_MAPKAPK_MK2_MAPKAPK2_ST	Q9Y580	RBM7	P49137	MAPKAPK2	S115	E118K	118	Missense	distal	3	no	11.996	11.869	EPSD	TCGA;COSMIC	11.681	Down-regulation
CAMK_MAPKAPK_MK2_MAPKAPK2_ST	Q9Y580	RBM7	P49137	MAPKAPK2	S136	P138L	138	Missense	proximal	2	no	19.857	19.634	EPSD;PhosphoSitePlus	TCGA;COSMIC	11.681	Down-regulation
CAMK_MAPKAPK_MK2_MAPKAPK2_ST	Q9Y580	RBM7	P49137	MAPKAPK2	S155	G158E	158	Missense	distal	3	no	15.293	15.376	EPSD	TCGA;COSMIC	11.681	Up-regulation
CAMK_MAPKAPK_MK2_MAPKAPK2_ST	Q9Y580	RBM7	P49137	MAPKAPK2	S178	S184C	184	Missense	distal	6	no	13.579	13.551	EPSD	TCGA;COSMIC	11.681	Down-regulation
CAMK_MAPKAPK_MK2_MAPKAPK2_ST	Q9Y580	RBM7	P49137	MAPKAPK2	S178	S185L	185	Missense	distal	7	no	13.579	13.223	EPSD	TCGA;COSMIC	11.681	Down-regulation
CAMK_MAPKAPK_MK2_MAPKAPK2_ST	Q9Y580	RBM7	P49137	MAPKAPK2	S178	S178N	178	Missense	central	0	yes	13.579	0.000	EPSD	TCGA	11.681	Loss
CAMK_MAPKAPK_MK2_MAPKAPK2_ST	Q9Y580	RBM7	P49137	MAPKAPK2	S180	S184C	184	Missense	distal	4	no	13.837	13.661	EPSD	TCGA;COSMIC	11.681	Down-regulation
CAMK_MAPKAPK_MK2_MAPKAPK2_ST	Q9Y580	RBM7	P49137	MAPKAPK2	S180	S185L	185	Missense	distal	5	no	13.837	14.007	EPSD	TCGA;COSMIC	11.681	Up-regulation
CAMK_MAPKAPK_MK2_MAPKAPK2_ST	Q9Y580	RBM7	P49137	MAPKAPK2	S180	S178N	178	Missense	proximal	-2	no	13.837	11.473	EPSD	TCGA	11.681	Loss
CAMK_MAPKAPK_MK2_MAPKAPK2_ST	Q9Y580	RBM7	P49137	MAPKAPK2	S186	S184C	184	Missense	proximal	-2	no	14.525	11.047	EPSD	TCGA;COSMIC	11.681	Loss
CAMK_MAPKAPK_MK2_MAPKAPK2_ST	Q9Y580	RBM7	P49137	MAPKAPK2	S186	Q191H	191	Missense	distal	5	no	14.525	14.612	EPSD	TCGA;COSMIC	11.681	Up-regulation
CAMK_MAPKAPK_MK2_MAPKAPK2_ST	Q9Y580	RBM7	P49137	MAPKAPK2	S186	W189R	189	Missense	distal	3	no	14.525	14.563	EPSD	TCGA;COSMIC	11.681	Up-regulation
CAMK_MAPKAPK_MK2_MAPKAPK2_ST	Q9Y580	RBM7	P49137	MAPKAPK2	S186	R190C	190	Missense	distal	4	no	14.525	14.412	EPSD	TCGA;COSMIC	11.681	Down-regulation
CAMK_MAPKAPK_MK2_MAPKAPK2_ST	Q9Y580	RBM7	P49137	MAPKAPK2	S204	S204Y	204	Missense	central	0	yes	16.724	0.000	PhosphoSitePlus;EPSD	TCGA;COSMIC	11.681	Loss
CAMK_MAPKAPK_MK2_MAPKAPK2_ST	Q9Y580	RBM7	P49137	MAPKAPK2	S204	R198H	198	Missense	distal	-6	no	16.724	16.788	PhosphoSitePlus;EPSD	TCGA;COSMIC	11.681	Up-regulation
CAMK_MAPKAPK_MK2_MAPKAPK2_ST	O00418	EEF2K	P49137	MAPKAPK2	S66	E67K	67	Missense	proximal	1	no	12.392	11.928	EPSD	TCGA;ICGC;COSMIC	11.681	Down-regulation
CAMK_MAPKAPK_MK2_MAPKAPK2_ST	O00418	EEF2K	P49137	MAPKAPK2	S66	S61G	61	Missense	distal	-5	no	12.392	11.513	EPSD	TCGA;ICGC	11.681	Loss
CAMK_MAPKAPK_MK2_MAPKAPK2_ST	O00418	EEF2K	P49137	MAPKAPK2	S66	R68W	68	Missense	proximal	2	no	12.392	12.082	EPSD	TCGA	11.681	Down-regulation
CAMK_MAPKAPK_MK2_MAPKAPK2_ST	O00418	EEF2K	P49137	MAPKAPK2	S66	S61I	61	Missense	distal	-5	no	12.392	12.698	EPSD	TCGA;ICGC	11.681	Up-regulation
CAMK_MAPKAPK_MK2_MAPKAPK2_ST	O00418	EEF2K	P49137	MAPKAPK2	S71	E67K	67	Missense	distal	-4	no	13.537	13.704	EPSD	TCGA;ICGC;COSMIC	11.681	Up-regulation
CAMK_MAPKAPK_MK2_MAPKAPK2_ST	O00418	EEF2K	P49137	MAPKAPK2	S71	R68W	68	Missense	distal	-3	no	13.537	4.958	EPSD	TCGA	11.681	Loss
CAMK_MAPKAPK_MK2_MAPKAPK2_ST	O00418	EEF2K	P49137	MAPKAPK2	S71	S74C	74	Missense	distal	3	no	13.537	13.418	EPSD	TCGA;ICGC;COSMIC	11.681	Down-regulation
CAMK_MAPKAPK_MK2_MAPKAPK2_ST	O00418	EEF2K	P49137	MAPKAPK2	S72	E67K	67	Missense	distal	-5	no	11.866	11.258	EPSD	TCGA;ICGC;COSMIC	11.681	Loss
CAMK_MAPKAPK_MK2_MAPKAPK2_ST	O00418	EEF2K	P49137	MAPKAPK2	S72	R68W	68	Missense	distal	-4	no	11.866	12.084	EPSD	TCGA	11.681	Up-regulation
CAMK_MAPKAPK_MK2_MAPKAPK2_ST	O00418	EEF2K	P49137	MAPKAPK2	S72	S74C	74	Missense	proximal	2	no	11.866	11.466	EPSD	TCGA;ICGC;COSMIC	11.681	Loss
CAMK_MAPKAPK_MK2_MAPKAPK2_ST	O00418	EEF2K	P49137	MAPKAPK2	S78	H80Y	80	Missense	proximal	2	no	11.838	11.763	EPSD	TCGA;ICGC;COSMIC	11.681	Down-regulation
CAMK_MAPKAPK_MK2_MAPKAPK2_ST	O00418	EEF2K	P49137	MAPKAPK2	S78	S74C	74	Missense	distal	-4	no	11.838	12.078	EPSD	TCGA;ICGC;COSMIC	11.681	Up-regulation
CAMK_MAPKAPK_MK2_MAPKAPK2_ST	O00418	EEF2K	P49137	MAPKAPK2	S366	S366F	366	Missense	central	0	yes	16.411	0.000	EPSD	TCGA;ICGC;COSMIC	11.681	Loss
CAMK_MAPKAPK_MK2_MAPKAPK2_ST	O00418	EEF2K	P49137	MAPKAPK2	S366	S366C	366	Missense	central	0	yes	16.411	0.000	EPSD	TCGA;ICGC;COSMIC	11.681	Loss
CAMK_MAPKAPK_MK2_MAPKAPK2_ST	O00418	EEF2K	P49137	MAPKAPK2	S366	P371S	371	Missense	distal	5	no	16.411	16.328	EPSD	TCGA;ICGC;COSMIC	11.681	Down-regulation
CAMK_MAPKAPK_MK2_MAPKAPK2_ST	O00418	EEF2K	P49137	MAPKAPK2	S368	S366F	366	Missense	proximal	-2	no	14.738	9.312	EPSD	TCGA;ICGC;COSMIC	11.681	Loss
CAMK_MAPKAPK_MK2_MAPKAPK2_ST	O00418	EEF2K	P49137	MAPKAPK2	S368	S366C	366	Missense	proximal	-2	no	14.738	11.260	EPSD	TCGA;ICGC;COSMIC	11.681	Loss
CAMK_MAPKAPK_MK2_MAPKAPK2_ST	O00418	EEF2K	P49137	MAPKAPK2	S368	P371S	371	Missense	distal	3	no	14.738	14.744	EPSD	TCGA;ICGC;COSMIC	11.681	Up-regulation
CAMK_MAPKAPK_MK2_MAPKAPK2_ST	O00418	EEF2K	P49137	MAPKAPK2	S377	P371S	371	Missense	distal	-6	no	17.589	17.588	PhosphoSitePlus	TCGA;ICGC;COSMIC	11.681	Down-regulation
CAMK_MAPKAPK_MK2_MAPKAPK2_ST	O00418	EEF2K	P49137	MAPKAPK2	S398	A400V	400	Missense	proximal	2	no	12.900	12.594	EPSD	TCGA;ICGC;COSMIC	11.681	Down-regulation
CAMK_MAPKAPK_MK2_MAPKAPK2_ST	O00418	EEF2K	P49137	MAPKAPK2	S398	S396F	396	Missense	proximal	-2	no	12.900	7.473	EPSD	TCGA;ICGC;COSMIC	11.681	Loss
CAMK_MAPKAPK_MK2_MAPKAPK2_ST	O00418	EEF2K	P49137	MAPKAPK2	S398	S392F	392	Missense	distal	-6	no	12.900	13.008	EPSD	TCGA;ICGC;COSMIC	11.681	Up-regulation
CAMK_MAPKAPK_MK2_MAPKAPK2_ST	O00418	EEF2K	P49137	MAPKAPK2	S398	D391N	391	Missense	distal	-7	no	12.900	12.910	EPSD	TCGA;ICGC	11.681	Up-regulation
CAMK_MAPKAPK_MK2_MAPKAPK2_ST	P07101	TH	P49137	MAPKAPK2	S19	A23T	23	Missense	distal	4	no	19.504	19.529	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	11.681	Up-regulation
CAMK_MAPKAPK_MK2_MAPKAPK2_ST	P07101	TH	P49137	MAPKAPK2	S19	R15H	15	Missense	distal	-4	no	19.504	19.743	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC;GDSC	11.681	Up-regulation
CAMK_MAPKAPK_MK2_MAPKAPK2_ST	P07101	TH	P49137	MAPKAPK2	S71	R64W	64	Missense	distal	-7	no	19.024	19.102	EPSD;PhosphoSitePlus	TCGA;COSMIC	11.681	Up-regulation
CAMK_MAPKAPK_MK2_MAPKAPK2_ST	P07101	TH	P49137	MAPKAPK2	S71	K78N	78	Missense	distal	7	no	19.024	18.929	EPSD;PhosphoSitePlus	TCGA;COSMIC	11.681	Down-regulation
CAMK_MAPKAPK_MK2_MAPKAPK2_ST	P07101	TH	P49137	MAPKAPK2	S118	S125L	125	Missense	distal	7	no	12.033	11.676	EPSD	TCGA;COSMIC	11.681	Loss
CAMK_MAPKAPK_MK2_MAPKAPK2_ST	P07101	TH	P49137	MAPKAPK2	S118	R120M	120	Missense	proximal	2	no	12.033	11.869	EPSD	TCGA;COSMIC	11.681	Down-regulation
CAMK_MAPKAPK_MK2_MAPKAPK2_ST	P07101	TH	P49137	MAPKAPK2	S118	A111T	111	Missense	distal	-7	no	12.033	12.012	EPSD	TCGA	11.681	Down-regulation
CAMK_MAPKAPK_MK2_MAPKAPK2_ST	P07101	TH	P49137	MAPKAPK2	S435	E436K	436	Missense	proximal	1	no	13.210	12.746	EPSD	TCGA;COSMIC	11.681	Down-regulation
CAMK_MAPKAPK_MK2_MAPKAPK2_ST	P07101	TH	P49137	MAPKAPK2	S435	R441P	441	Missense	distal	6	no	13.210	13.197	EPSD	TCGA;COSMIC	11.681	Down-regulation
CAMK_MAPKAPK_MK2_MAPKAPK2_ST	P07101	TH	P49137	MAPKAPK2	S435	G428R	428	Missense	distal	-7	no	13.210	13.118	EPSD	TCGA;COSMIC	11.681	Down-regulation
CAMK_MAPKAPK_MK2_MAPKAPK2_ST	P05783	KRT18	P49137	MAPKAPK2	S30	P28L	28	Missense	proximal	-2	no	16.484	16.358	EPSD	TCGA;ICGC;COSMIC	11.681	Down-regulation
CAMK_MAPKAPK_MK2_MAPKAPK2_ST	P05783	KRT18	P49137	MAPKAPK2	S34	P28L	28	Missense	distal	-6	no	11.834	11.865	EPSD	TCGA;ICGC;COSMIC	11.681	Up-regulation
CAMK_MAPKAPK_MK2_MAPKAPK2_ST	P05783	KRT18	P49137	MAPKAPK2	S34	G41D	41	Missense	distal	7	no	11.834	11.926	EPSD	TCGA;ICGC;COSMIC	11.681	Up-regulation
CAMK_MAPKAPK_MK2_MAPKAPK2_ST	P05783	KRT18	P49137	MAPKAPK2	S34	G38D	38	Missense	distal	4	no	11.834	11.828	EPSD	TCGA;ICGC;COSMIC	11.681	Down-regulation
CAMK_MAPKAPK_MK2_MAPKAPK2_ST	P05783	KRT18	P49137	MAPKAPK2	S44	G41D	41	Missense	distal	-3	no	8.535	12.076	EPSD	TCGA;ICGC;COSMIC	11.681	Gain
CAMK_MAPKAPK_MK2_MAPKAPK2_ST	P05783	KRT18	P49137	MAPKAPK2	S53	G57D	57	Missense	distal	4	no	19.256	19.250	PhosphoSitePlus	TCGA;ICGC;COSMIC	11.681	Down-regulation
CAMK_MAPKAPK_MK2_MAPKAPK2_ST	P05783	KRT18	P49137	MAPKAPK2	S53	S60Y	60	Missense	distal	7	no	19.256	18.761	PhosphoSitePlus	TCGA;ICGC;COSMIC	11.681	Down-regulation
CAMK_MAPKAPK_MK2_MAPKAPK2_ST	P05783	KRT18	P49137	MAPKAPK2	S127	P121S	121	Missense	distal	-6	no	12.738	12.737	EPSD	TCGA;ICGC;COSMIC	11.681	Down-regulation
CAMK_MAPKAPK_MK2_MAPKAPK2_ST	P05783	KRT18	P49137	MAPKAPK2	S127	G120E	120	Missense	distal	-7	no	12.738	12.680	EPSD	TCGA	11.681	Down-regulation
CAMK_MAPKAPK_MK2_MAPKAPK2_ST	P18615	NELFE	P49137	MAPKAPK2	S51	R48C	48	Missense	distal	-3	no	21.458	13.058	PhosphoSitePlus;EPSD	TCGA;COSMIC	11.681	Down-regulation
CAMK_MAPKAPK_MK2_MAPKAPK2_ST	P18615	NELFE	P49137	MAPKAPK2	T91	S89C	89	Missense	proximal	-2	no	15.610	12.132	EPSD	TCGA;COSMIC	11.681	Down-regulation
CAMK_MAPKAPK_MK2_MAPKAPK2_ST	P18615	NELFE	P49137	MAPKAPK2	T91	E93Q	93	Missense	proximal	2	no	15.610	15.409	EPSD	TCGA;COSMIC	11.681	Down-regulation
CAMK_MAPKAPK_MK2_MAPKAPK2_ST	P18615	NELFE	P49137	MAPKAPK2	T91	R88C	88	Missense	distal	-3	no	15.610	7.210	EPSD	TCGA;COSMIC	11.681	Loss
CAMK_MAPKAPK_MK2_MAPKAPK2_ST	P18615	NELFE	P49137	MAPKAPK2	S115	R112T	112	Missense	distal	-3	no	17.486	11.611	EPSD;PhosphoSitePlus	TCGA;COSMIC	11.681	Loss
CAMK_MAPKAPK_MK2_MAPKAPK2_ST	P18615	NELFE	P49137	MAPKAPK2	S123	R126H	126	Missense	distal	3	no	13.347	13.210	EPSD	TCGA	11.681	Down-regulation
CAMK_MAPKAPK_MK2_MAPKAPK2_ST	P18615	NELFE	P49137	MAPKAPK2	S181	P183L	183	Missense	proximal	2	no	13.293	13.070	EPSD	TCGA;COSMIC	11.681	Down-regulation
CAMK_MAPKAPK_MK2_MAPKAPK2_ST	P18615	NELFE	P49137	MAPKAPK2	S187	P183L	183	Missense	distal	-4	no	19.365	19.489	EPSD	TCGA;COSMIC	11.681	Up-regulation
CAMK_MAPKAPK_MK2_MAPKAPK2_ST	P18615	NELFE	P49137	MAPKAPK2	S187	R194K	194	Missense	distal	7	no	19.365	19.142	EPSD	TCGA;COSMIC	11.681	Down-regulation
CAMK_MAPKAPK_MK2_MAPKAPK2_ST	P18615	NELFE	P49137	MAPKAPK2	S191	D197N	197	Missense	distal	6	no	15.717	15.724	EPSD	TCGA	11.681	Up-regulation
CAMK_MAPKAPK_MK2_MAPKAPK2_ST	P18615	NELFE	P49137	MAPKAPK2	S191	R194K	194	Missense	distal	3	no	15.717	15.642	EPSD	TCGA;COSMIC	11.681	Down-regulation
CAMK_MAPKAPK_MK2_MAPKAPK2_ST	P18615	NELFE	P49137	MAPKAPK2	S251	R255W	255	Missense	distal	4	no	19.741	19.631	EPSD;PhosphoSitePlus	TCGA	11.681	Down-regulation
CAMK_MAPKAPK_MK2_MAPKAPK2_ST	P18615	NELFE	P49137	MAPKAPK2	S251	R256Q	256	Missense	distal	5	no	19.741	19.960	EPSD;PhosphoSitePlus	TCGA;COSMIC	11.681	Up-regulation
CAMK_MAPKAPK_MK2_MAPKAPK2_ST	P18615	NELFE	P49137	MAPKAPK2	S251	S251L	251	Missense	central	0	yes	19.741	0.000	EPSD;PhosphoSitePlus	TCGA;COSMIC	11.681	Loss
CAMK_MAPKAPK_MK2_MAPKAPK2_ST	P18615	NELFE	P49137	MAPKAPK2	S251	D250E	250	Missense	proximal	-1	no	19.741	19.729	EPSD;PhosphoSitePlus	TCGA;COSMIC	11.681	Down-regulation
CAMK_MAPKAPK_MK2_MAPKAPK2_ST	P49137	MAPKAPK2	P49137	MAPKAPK2	S328	H322Y	322	Missense	distal	-6	no	12.202	12.228	EPSD	TCGA;ICGC;GDSC;CCLE	11.681	Up-regulation
CAMK_MAPKAPK_MK2_MAPKAPK2_ST	Q07352	ZFP36L1	P49137	MAPKAPK2	S54	R51W	51	Missense	distal	-3	no	16.902	8.323	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	11.681	Loss
CAMK_MAPKAPK_MK2_MAPKAPK2_ST	Q07352	ZFP36L1	P49137	MAPKAPK2	S54	V55D	55	Missense	proximal	1	no	16.902	16.361	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	11.681	Down-regulation
CAMK_MAPKAPK_MK2_MAPKAPK2_ST	Q07352	ZFP36L1	P49137	MAPKAPK2	S90	R87G	87	Missense	distal	-3	no	15.713	5.053	EPSD	TCGA;ICGC;COSMIC	11.681	Loss
CAMK_MAPKAPK_MK2_MAPKAPK2_ST	Q07352	ZFP36L1	P49137	MAPKAPK2	S90	G95V	95	Missense	distal	5	no	15.713	15.606	EPSD	TCGA;ICGC;COSMIC	11.681	Down-regulation
CAMK_MAPKAPK_MK2_MAPKAPK2_ST	Q07352	ZFP36L1	P49137	MAPKAPK2	S90	R87Q	87	Missense	distal	-3	no	15.713	9.949	EPSD	TCGA;ICGC;COSMIC	11.681	Loss
CAMK_MAPKAPK_MK2_MAPKAPK2_ST	Q07352	ZFP36L1	P49137	MAPKAPK2	S90	D83H	83	Missense	distal	-7	no	15.713	15.730	EPSD	TCGA;ICGC;COSMIC	11.681	Up-regulation
CAMK_MAPKAPK_MK2_MAPKAPK2_ST	Q07352	ZFP36L1	P49137	MAPKAPK2	S92	R87G	87	Missense	distal	-5	no	20.305	19.272	PhosphoSitePlus;EPSD	TCGA;ICGC;COSMIC	11.681	Down-regulation
CAMK_MAPKAPK_MK2_MAPKAPK2_ST	Q07352	ZFP36L1	P49137	MAPKAPK2	S92	G95V	95	Missense	distal	3	no	20.305	20.346	PhosphoSitePlus;EPSD	TCGA;ICGC;COSMIC	11.681	Up-regulation
CAMK_MAPKAPK_MK2_MAPKAPK2_ST	Q07352	ZFP36L1	P49137	MAPKAPK2	S92	L98M	98	Missense	distal	6	no	20.305	20.308	PhosphoSitePlus;EPSD	TCGA;ICGC	11.681	Up-regulation
CAMK_MAPKAPK_MK2_MAPKAPK2_ST	Q07352	ZFP36L1	P49137	MAPKAPK2	S92	R87Q	87	Missense	distal	-5	no	20.305	19.587	PhosphoSitePlus;EPSD	TCGA;ICGC;COSMIC	11.681	Down-regulation
CAMK_MAPKAPK_MK2_MAPKAPK2_ST	Q07352	ZFP36L1	P49137	MAPKAPK2	S192	A186T	186	Missense	distal	-6	no	12.901	12.871	EPSD	TCGA;ICGC;COSMIC	11.681	Down-regulation
CAMK_MAPKAPK_MK2_MAPKAPK2_ST	Q07352	ZFP36L1	P49137	MAPKAPK2	S201	S201R	201	Missense	central	0	yes	12.685	0.000	EPSD	TCGA;ICGC;COSMIC	11.681	Loss
CAMK_MAPKAPK_MK2_MAPKAPK2_ST	Q07352	ZFP36L1	P49137	MAPKAPK2	S203	S201R	201	Missense	proximal	-2	no	15.900	13.634	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	11.681	Down-regulation
CAMK_MAPKAPK_MK2_MAPKAPK2_ST	Q07352	ZFP36L1	P49137	MAPKAPK2	S283	P281L	281	Missense	proximal	-2	no	17.575	17.449	EPSD	TCGA;ICGC;COSMIC	11.681	Down-regulation
CAMK_MAPKAPK_MK2_MAPKAPK2_ST	Q07352	ZFP36L1	P49137	MAPKAPK2	S283	M288T	288	Missense	distal	5	no	17.575	17.394	EPSD	TCGA;ICGC;COSMIC;CCLE	11.681	Down-regulation
CAMK_MAPKAPK_MK2_MAPKAPK2_ST	Q07352	ZFP36L1	P49137	MAPKAPK2	S283	L278I	278	Missense	distal	-5	no	17.575	17.387	EPSD	TCGA;ICGC;COSMIC	11.681	Down-regulation
CAMK_MAPKAPK_MK2_MAPKAPK2_ST	Q07352	ZFP36L1	P49137	MAPKAPK2	S314	S312R	312	Missense	proximal	-2	no	11.767	9.500	EPSD	TCGA;ICGC;COSMIC	11.681	Loss
CAMK_MAPKAPK_MK2_MAPKAPK2_ST	Q07352	ZFP36L1	P49137	MAPKAPK2	S314	S318F	318	Missense	distal	4	no	11.767	11.456	EPSD	TCGA;ICGC;COSMIC;GDSC;CCLE	11.681	Loss
CAMK_MAPKAPK_MK2_MAPKAPK2_ST	Q07352	ZFP36L1	P49137	MAPKAPK2	S316	S312R	312	Missense	distal	-4	no	14.018	14.030	EPSD	TCGA;ICGC;COSMIC	11.681	Up-regulation
CAMK_MAPKAPK_MK2_MAPKAPK2_ST	Q07352	ZFP36L1	P49137	MAPKAPK2	S316	S318F	318	Missense	proximal	2	no	14.018	13.304	EPSD	TCGA;ICGC;COSMIC;GDSC;CCLE	11.681	Down-regulation
CAMK_MAPKAPK_MK2_MAPKAPK2_ST	Q9NQC3	RTN4	P49137	MAPKAPK2	S15	P8S	8	Missense	distal	-7	no	12.823	12.825	EPSD	TCGA;ICGC;COSMIC	11.681	Up-regulation
CAMK_MAPKAPK_MK2_MAPKAPK2_ST	Q9NQC3	RTN4	P49137	MAPKAPK2	S196	E197V	197	Missense	proximal	1	no	14.712	14.819	EPSD	TCGA;ICGC;COSMIC	11.681	Up-regulation
CAMK_MAPKAPK_MK2_MAPKAPK2_ST	Q9NQC3	RTN4	P49137	MAPKAPK2	S239	S234C	234	Missense	distal	-5	no	13.945	13.494	EPSD	TCGA;COSMIC	11.681	Down-regulation
CAMK_MAPKAPK_MK2_MAPKAPK2_ST	Q9NQC3	RTN4	P49137	MAPKAPK2	S239	L238P	238	Missense	proximal	-1	no	13.945	13.946	EPSD	TCGA;COSMIC;CCLE	11.681	Up-regulation
CAMK_MAPKAPK_MK2_MAPKAPK2_ST	Q9NQC3	RTN4	P49137	MAPKAPK2	S245	L238P	238	Missense	distal	-7	no	11.788	11.753	EPSD	TCGA;COSMIC;CCLE	11.681	Down-regulation
CAMK_MAPKAPK_MK2_MAPKAPK2_ST	Q9NQC3	RTN4	P49137	MAPKAPK2	S440	E439Q	439	Missense	proximal	-1	no	12.476	12.489	EPSD	TCGA;COSMIC	11.681	Up-regulation
CAMK_MAPKAPK_MK2_MAPKAPK2_ST	Q9NQC3	RTN4	P49137	MAPKAPK2	S440	S440R	440	Missense	central	0	yes	12.476	0.000	EPSD	TCGA;COSMIC	11.681	Loss
CAMK_MAPKAPK_MK2_MAPKAPK2_ST	Q9NQC3	RTN4	P49137	MAPKAPK2	S440	S438I	438	Missense	proximal	-2	no	12.476	8.134	EPSD	TCGA	11.681	Loss
CAMK_MAPKAPK_MK2_MAPKAPK2_ST	Q9NQC3	RTN4	P49137	MAPKAPK2	S440	E435K	435	Missense	distal	-5	no	12.476	11.868	EPSD	TCGA;COSMIC	11.681	Down-regulation
CAMK_MAPKAPK_MK2_MAPKAPK2_ST	Q9NQC3	RTN4	P49137	MAPKAPK2	S525	A522T	522	Missense	distal	-3	no	8.920	12.266	EPSD	TCGA	11.681	Gain
CAMK_MAPKAPK_MK2_MAPKAPK2_ST	Q9NQC3	RTN4	P49137	MAPKAPK2	S881	L885V	885	Missense	distal	4	no	13.058	13.083	EPSD	TCGA;COSMIC	11.681	Up-regulation
CAMK_MAPKAPK_MK2_MAPKAPK2_ST	Q9NQC3	RTN4	P49137	MAPKAPK2	T890	L885V	885	Missense	distal	-5	no	12.221	11.914	EPSD	TCGA;COSMIC	11.681	Down-regulation
CAMK_MAPKAPK_MK2_MAPKAPK2_ST	Q9NQC3	RTN4	P49137	MAPKAPK2	S993	I995V	995	Missense	proximal	2	no	18.917	19.000	EPSD	TCGA;COSMIC	11.681	Up-regulation
CAMK_MAPKAPK_MK2_MAPKAPK2_ST	Q9NQC3	RTN4	P49137	MAPKAPK2	S993	A998V	998	Missense	distal	5	no	18.917	19.061	EPSD	TCGA	11.681	Up-regulation
CAMK_MAPKAPK_MK2_MAPKAPK2_ST	Q9NQC3	RTN4	P49137	MAPKAPK2	S1094	A1095D	1095	Missense	proximal	1	no	12.406	12.115	EPSD	TCGA;COSMIC	11.681	Down-regulation
CAMK_MAPKAPK_MK2_MAPKAPK2_ST	P53350	PLK1	P49137	MAPKAPK2	S137	R134H	134	Missense	distal	-3	no	16.932	12.173	EPSD	TCGA;ICGC	11.681	Down-regulation
CAMK_MAPKAPK_MK2_MAPKAPK2_ST	P53350	PLK1	P49137	MAPKAPK2	S326	L319M	319	Missense	distal	-7	no	12.908	12.906	PhosphoSitePlus;EPSD	TCGA;ICGC;COSMIC	11.681	Down-regulation
CAMK_MAPKAPK_MK2_MAPKAPK2_ST	P53350	PLK1	P49137	MAPKAPK2	S326	S326L	326	Missense	central	0	yes	12.908	0.000	PhosphoSitePlus;EPSD	TCGA;ICGC;COSMIC;CCLE	11.681	Loss
CAMK_MAPKAPK_MK2_MAPKAPK2_ST	P53350	PLK1	P49137	MAPKAPK2	S326	P323L	323	Missense	distal	-3	no	12.908	12.482	PhosphoSitePlus;EPSD	TCGA;ICGC;COSMIC	11.681	Down-regulation
CAMK_MAPKAPK_MK2_MAPKAPK2_ST	P53350	PLK1	P49137	MAPKAPK2	S330	S335C	335	Missense	distal	5	no	12.702	12.946	EPSD	TCGA;ICGC;COSMIC	11.681	Up-regulation
CAMK_MAPKAPK_MK2_MAPKAPK2_ST	P53350	PLK1	P49137	MAPKAPK2	S330	S326L	326	Missense	distal	-4	no	12.702	12.906	EPSD	TCGA;ICGC;COSMIC;CCLE	11.681	Up-regulation
CAMK_MAPKAPK_MK2_MAPKAPK2_ST	P53350	PLK1	P49137	MAPKAPK2	S330	P323L	323	Missense	distal	-7	no	12.702	12.736	EPSD	TCGA;ICGC;COSMIC	11.681	Up-regulation
CAMK_MAPKAPK_MK2_MAPKAPK2_ST	P53350	PLK1	P49137	MAPKAPK2	S330	R337W	337	Missense	distal	7	no	12.702	12.429	EPSD	TCGA;ICGC;COSMIC	11.681	Down-regulation
CAMK_MAPKAPK_MK2_MAPKAPK2_ST	P53350	PLK1	P49137	MAPKAPK2	S565	R560H	560	Missense	distal	-5	no	12.059	11.581	EPSD	TCGA;ICGC;COSMIC	11.681	Loss
CAMK_MAPKAPK_MK2_MAPKAPK2_ST	P53350	PLK1	P49137	MAPKAPK2	S592	R594C	594	Missense	proximal	2	no	12.258	11.962	EPSD	TCGA;ICGC;COSMIC	11.681	Down-regulation
CAMK_MAPKAPK_MK2_MAPKAPK2_ST	P53350	PLK1	P49137	MAPKAPK2	S597	R594C	594	Missense	distal	-3	no	18.136	9.737	EPSD	TCGA;ICGC;COSMIC	11.681	Loss
CAMK_MAPKAPK_MK2_MAPKAPK2_ST	P31749	AKT1	P49137	MAPKAPK2	S124	R121W	121	Missense	distal	-3	no	19.183	10.604	EPSD	TCGA;ICGC;COSMIC	11.681	Loss
CAMK_MAPKAPK_MK2_MAPKAPK2_ST	P31749	AKT1	P49137	MAPKAPK2	S124	A131T	131	Missense	distal	7	no	19.183	19.284	EPSD	TCGA;ICGC;COSMIC	11.681	Up-regulation
CAMK_MAPKAPK_MK2_MAPKAPK2_ST	P31749	AKT1	P49137	MAPKAPK2	S473	S475L	475	Missense	proximal	2	no	12.620	12.205	PhosphoSitePlus	TCGA;ICGC;COSMIC	11.681	Down-regulation
CAMK_MAPKAPK_MK2_MAPKAPK2_ST	P31749	AKT1	P49137	MAPKAPK2	S477	S475L	475	Missense	proximal	-2	no	12.069	8.712	EPSD	TCGA;ICGC;COSMIC	11.681	Loss
CAMK_MAPKAPK_MK2_MAPKAPK2_ST	P04637	TP53	P49137	MAPKAPK2	S20	P27S	27	Missense	distal	7	no	12.451	12.334	PhosphoSitePlus	TCGA;ICGC;COSMIC	11.681	Down-regulation
CAMK_MAPKAPK_MK2_MAPKAPK2_ST	P04637	TP53	P49137	MAPKAPK2	S20	P27L	27	Missense	distal	7	no	12.451	11.978	PhosphoSitePlus	TCGA;ICGC;COSMIC;GDSC;CCLE	11.681	Down-regulation
CAMK_MAPKAPK_MK2_MAPKAPK2_ST	P04637	TP53	P49137	MAPKAPK2	S183	H179R	179	Missense	distal	-4	no	12.691	12.452	EPSD	TCGA;ICGC;COSMIC;GDSC;CCLE	11.681	Down-regulation
CAMK_MAPKAPK_MK2_MAPKAPK2_ST	P04637	TP53	P49137	MAPKAPK2	S183	C176F	176	Missense	distal	-7	no	12.691	12.736	EPSD	TCGA;ICGC;COSMIC;GDSC;CCLE	11.681	Up-regulation
CAMK_MAPKAPK_MK2_MAPKAPK2_ST	P04637	TP53	P49137	MAPKAPK2	S183	R181H	181	Missense	proximal	-2	no	12.691	10.260	EPSD	TCGA;ICGC;COSMIC;CCLE	11.681	Loss
CAMK_MAPKAPK_MK2_MAPKAPK2_ST	P04637	TP53	P49137	MAPKAPK2	S183	G187S	187	Missense	distal	4	no	12.691	12.880	EPSD	TCGA;ICGC;COSMIC	11.681	Up-regulation
CAMK_MAPKAPK_MK2_MAPKAPK2_ST	P04637	TP53	P49137	MAPKAPK2	S183	H179Y	179	Missense	distal	-4	no	12.691	12.784	EPSD	TCGA;ICGC;COSMIC	11.681	Up-regulation
CAMK_MAPKAPK_MK2_MAPKAPK2_ST	P04637	TP53	P49137	MAPKAPK2	S183	C176Y	176	Missense	distal	-7	no	12.691	12.722	EPSD	TCGA;ICGC;COSMIC;GDSC;CCLE	11.681	Up-regulation
CAMK_MAPKAPK_MK2_MAPKAPK2_ST	P04637	TP53	P49137	MAPKAPK2	S183	P190L	190	Missense	distal	7	no	12.691	12.218	EPSD	TCGA;ICGC;COSMIC;CCLE	11.681	Down-regulation
CAMK_MAPKAPK_MK2_MAPKAPK2_ST	P04637	TP53	P49137	MAPKAPK2	S183	H178Q	178	Missense	distal	-5	no	12.691	12.451	EPSD	TCGA;ICGC;COSMIC	11.681	Down-regulation
CAMK_MAPKAPK_MK2_MAPKAPK2_ST	P04637	TP53	P49137	MAPKAPK2	S183	E180K	180	Missense	distal	-3	no	12.691	12.863	EPSD	TCGA;ICGC;COSMIC;CCLE	11.681	Up-regulation
CAMK_MAPKAPK_MK2_MAPKAPK2_ST	P04637	TP53	P49137	MAPKAPK2	S183	C176S	176	Missense	distal	-7	no	12.691	12.647	EPSD	TCGA;ICGC;COSMIC;GDSC;CCLE	11.681	Down-regulation
CAMK_MAPKAPK_MK2_MAPKAPK2_ST	P04637	TP53	P49137	MAPKAPK2	S183	H179N	179	Missense	distal	-4	no	12.691	12.662	EPSD	TCGA;ICGC;COSMIC	11.681	Down-regulation
CAMK_MAPKAPK_MK2_MAPKAPK2_ST	P04637	TP53	P49137	MAPKAPK2	S183	H179P	179	Missense	distal	-4	no	12.691	12.520	EPSD	TCGA;ICGC;COSMIC	11.681	Down-regulation
CAMK_MAPKAPK_MK2_MAPKAPK2_ST	P04637	TP53	P49137	MAPKAPK2	S183	H179L	179	Missense	distal	-4	no	12.691	12.644	EPSD	TCGA;ICGC;COSMIC	11.681	Down-regulation
CAMK_MAPKAPK_MK2_MAPKAPK2_ST	P04637	TP53	P49137	MAPKAPK2	S183	H179D	179	Missense	distal	-4	no	12.691	12.700	EPSD	TCGA;ICGC;COSMIC;GDSC;CCLE	11.681	Up-regulation
CAMK_MAPKAPK_MK2_MAPKAPK2_ST	P04637	TP53	P49137	MAPKAPK2	S183	P190R	190	Missense	distal	7	no	12.691	12.603	EPSD	TCGA;ICGC;COSMIC	11.681	Down-regulation
CAMK_MAPKAPK_MK2_MAPKAPK2_ST	P04637	TP53	P49137	MAPKAPK2	S183	P177R	177	Missense	distal	-6	no	12.691	12.704	EPSD	TCGA;ICGC;COSMIC	11.681	Up-regulation
CAMK_MAPKAPK_MK2_MAPKAPK2_ST	P04637	TP53	P49137	MAPKAPK2	S183	P177H	177	Missense	distal	-6	no	12.691	12.768	EPSD	TCGA;ICGC;COSMIC	11.681	Up-regulation
CAMK_MAPKAPK_MK2_MAPKAPK2_ST	P04637	TP53	P49137	MAPKAPK2	S183	H179Q	179	Missense	distal	-4	no	12.691	12.641	EPSD	TCGA;ICGC;COSMIC;GDSC;CCLE	11.681	Down-regulation
CAMK_MAPKAPK_MK2_MAPKAPK2_ST	P04637	TP53	P49137	MAPKAPK2	S183	P177T	177	Missense	distal	-6	no	12.691	12.676	EPSD	TCGA;ICGC;COSMIC;GDSC;CCLE	11.681	Down-regulation
CAMK_MAPKAPK_MK2_MAPKAPK2_ST	P04637	TP53	P49137	MAPKAPK2	S183	R181P	181	Missense	proximal	-2	no	12.691	11.727	EPSD	TCGA;ICGC;COSMIC;CCLE	11.681	Down-regulation
CAMK_MAPKAPK_MK2_MAPKAPK2_ST	P04637	TP53	P49137	MAPKAPK2	S183	C176R	176	Missense	distal	-7	no	12.691	12.612	EPSD	TCGA;ICGC;COSMIC	11.681	Down-regulation
CAMK_MAPKAPK_MK2_MAPKAPK2_ST	P04637	TP53	P49137	MAPKAPK2	S183	R181C	181	Missense	proximal	-2	no	12.691	11.480	EPSD	TCGA;ICGC;COSMIC;GDSC;CCLE	11.681	Loss
CAMK_MAPKAPK_MK2_MAPKAPK2_ST	P04637	TP53	P49137	MAPKAPK2	S183	P177L	177	Missense	distal	-6	no	12.691	12.723	EPSD	TCGA;ICGC;COSMIC;GDSC;CCLE	11.681	Up-regulation
CAMK_MAPKAPK_MK2_MAPKAPK2_ST	P04637	TP53	P49137	MAPKAPK2	S269	G266E	266	Missense	distal	-3	no	8.205	13.569	EPSD	TCGA;ICGC;COSMIC;GDSC;CCLE	11.681	Gain
CAMK_MAPKAPK_MK2_MAPKAPK2_ST	P04637	TP53	P49137	MAPKAPK2	S269	G266R	266	Missense	distal	-3	no	8.205	18.865	EPSD	TCGA;ICGC;COSMIC;GDSC;CCLE	11.681	Gain
CAMK_MAPKAPK_MK2_MAPKAPK2_ST	P04637	TP53	P49137	MAPKAPK2	S314	K319N	319	Missense	distal	5	no	12.556	12.490	EPSD	TCGA;ICGC;COSMIC	11.681	Down-regulation
CAMK_MAPKAPK_MK2_MAPKAPK2_ST	P04637	TP53	P49137	MAPKAPK2	S314	A307V	307	Missense	distal	-7	no	12.556	12.599	EPSD	TCGA;ICGC;COSMIC;GDSC	11.681	Up-regulation
CAMK_MAPKAPK_MK2_MAPKAPK2_ST	P04637	TP53	P49137	MAPKAPK2	S314	K320E	320	Missense	distal	6	no	12.556	12.570	EPSD	TCGA;ICGC;COSMIC	11.681	Up-regulation
CAMK_MAPKAPK_MK2_MAPKAPK2_ST	P04637	TP53	P49137	MAPKAPK2	S314	S315C	315	Missense	proximal	1	no	12.556	12.317	EPSD	TCGA;ICGC;COSMIC	11.681	Down-regulation
CAMK_MAPKAPK_MK2_MAPKAPK2_ST	P04637	TP53	P49137	MAPKAPK2	S315	K319N	319	Missense	distal	4	no	12.896	12.941	EPSD	TCGA;ICGC;COSMIC	11.681	Up-regulation
CAMK_MAPKAPK_MK2_MAPKAPK2_ST	P04637	TP53	P49137	MAPKAPK2	S315	K320E	320	Missense	distal	5	no	12.896	12.682	EPSD	TCGA;ICGC;COSMIC	11.681	Down-regulation
CAMK_MAPKAPK_MK2_MAPKAPK2_ST	P04637	TP53	P49137	MAPKAPK2	S315	S315C	315	Missense	central	0	yes	12.896	0.000	EPSD	TCGA;ICGC;COSMIC	11.681	Loss
CAMK_MAPKAPK_MK2_MAPKAPK2_ST	P04637	TP53	P49137	MAPKAPK2	S378	S376C	376	Missense	proximal	-2	no	13.171	9.693	EPSD	TCGA;ICGC;COSMIC	11.681	Loss
CAMK_MAPKAPK_MK2_MAPKAPK2_ST	P04637	TP53	P49137	MAPKAPK2	S378	Q375K	375	Missense	distal	-3	no	13.171	13.811	EPSD	TCGA;ICGC;COSMIC	11.681	Up-regulation
CAMK_MAPKAPK_MK2_MAPKAPK2_ST	Q14134	TRIM29	P49137	MAPKAPK2	S21	S23L	23	Missense	proximal	2	no	12.763	12.348	EPSD	TCGA;ICGC;COSMIC	11.681	Down-regulation
CAMK_MAPKAPK_MK2_MAPKAPK2_ST	Q14134	TRIM29	P49137	MAPKAPK2	S21	R20G	20	Missense	proximal	-1	no	12.763	12.790	EPSD	TCGA;ICGC	11.681	Up-regulation
CAMK_MAPKAPK_MK2_MAPKAPK2_ST	Q14134	TRIM29	P49137	MAPKAPK2	S21	S26N	26	Missense	distal	5	no	12.763	13.002	EPSD	TCGA;ICGC;COSMIC	11.681	Up-regulation
CAMK_MAPKAPK_MK2_MAPKAPK2_ST	Q14134	TRIM29	P49137	MAPKAPK2	S21	G24D	24	Missense	distal	3	no	12.763	12.753	EPSD	TCGA;ICGC;COSMIC	11.681	Down-regulation
CAMK_MAPKAPK_MK2_MAPKAPK2_ST	Q14134	TRIM29	P49137	MAPKAPK2	S23	S23L	23	Missense	central	0	yes	18.844	0.000	EPSD	TCGA;ICGC;COSMIC	11.681	Loss
CAMK_MAPKAPK_MK2_MAPKAPK2_ST	Q14134	TRIM29	P49137	MAPKAPK2	S23	R20G	20	Missense	distal	-3	no	18.844	8.185	EPSD	TCGA;ICGC	11.681	Loss
CAMK_MAPKAPK_MK2_MAPKAPK2_ST	Q14134	TRIM29	P49137	MAPKAPK2	S23	S26N	26	Missense	distal	3	no	18.844	18.688	EPSD	TCGA;ICGC;COSMIC	11.681	Down-regulation
CAMK_MAPKAPK_MK2_MAPKAPK2_ST	Q14134	TRIM29	P49137	MAPKAPK2	S23	G24D	24	Missense	proximal	1	no	18.844	18.914	EPSD	TCGA;ICGC;COSMIC	11.681	Up-regulation
CAMK_MAPKAPK_MK2_MAPKAPK2_ST	Q14134	TRIM29	P49137	MAPKAPK2	S26	S23L	23	Missense	distal	-3	no	10.675	11.914	EPSD	TCGA;ICGC;COSMIC	11.681	Gain
CAMK_MAPKAPK_MK2_MAPKAPK2_ST	Q14134	TRIM29	P49137	MAPKAPK2	S28	S23L	23	Missense	distal	-5	no	16.012	16.506	EPSD	TCGA;ICGC;COSMIC	11.681	Up-regulation
CAMK_MAPKAPK_MK2_MAPKAPK2_ST	Q14134	TRIM29	P49137	MAPKAPK2	S28	S26N	26	Missense	proximal	-2	no	16.012	13.647	EPSD	TCGA;ICGC;COSMIC	11.681	Down-regulation
CAMK_MAPKAPK_MK2_MAPKAPK2_ST	Q14134	TRIM29	P49137	MAPKAPK2	S28	G24D	24	Missense	distal	-4	no	16.012	15.934	EPSD	TCGA;ICGC;COSMIC	11.681	Down-regulation
CAMK_MAPKAPK_MK2_MAPKAPK2_ST	Q14134	TRIM29	P49137	MAPKAPK2	S141	E147K	147	Missense	distal	6	no	12.305	12.291	EPSD	TCGA;ICGC;COSMIC	11.681	Down-regulation
CAMK_MAPKAPK_MK2_MAPKAPK2_ST	Q14134	TRIM29	P49137	MAPKAPK2	S141	R136Q	136	Missense	distal	-5	no	12.305	11.587	EPSD	TCGA;ICGC;COSMIC	11.681	Loss
CAMK_MAPKAPK_MK2_MAPKAPK2_ST	Q14134	TRIM29	P49137	MAPKAPK2	S141	G146R	146	Missense	distal	5	no	12.305	12.035	EPSD	TCGA;ICGC;COSMIC	11.681	Down-regulation
CAMK_MAPKAPK_MK2_MAPKAPK2_ST	Q14134	TRIM29	P49137	MAPKAPK2	S152	D157N	157	Missense	distal	5	no	17.151	17.117	EPSD	TCGA;ICGC;COSMIC	11.681	Down-regulation
CAMK_MAPKAPK_MK2_MAPKAPK2_ST	Q14134	TRIM29	P49137	MAPKAPK2	S152	A156V	156	Missense	distal	4	no	17.151	17.000	EPSD	TCGA;ICGC;COSMIC	11.681	Down-regulation
CAMK_MAPKAPK_MK2_MAPKAPK2_ST	Q14134	TRIM29	P49137	MAPKAPK2	S152	R150Q	150	Missense	proximal	-2	no	17.151	17.158	EPSD	TCGA;ICGC;COSMIC	11.681	Up-regulation
CAMK_MAPKAPK_MK2_MAPKAPK2_ST	Q14134	TRIM29	P49137	MAPKAPK2	S152	E147K	147	Missense	distal	-5	no	17.151	16.543	EPSD	TCGA;ICGC;COSMIC	11.681	Down-regulation
CAMK_MAPKAPK_MK2_MAPKAPK2_ST	Q14134	TRIM29	P49137	MAPKAPK2	S152	G146R	146	Missense	distal	-6	no	17.151	17.079	EPSD	TCGA;ICGC;COSMIC	11.681	Down-regulation
CAMK_MAPKAPK_MK2_MAPKAPK2_ST	Q14134	TRIM29	P49137	MAPKAPK2	T158	D157N	157	Missense	proximal	-1	no	13.302	13.303	EPSD	TCGA;ICGC;COSMIC	11.681	Up-regulation
CAMK_MAPKAPK_MK2_MAPKAPK2_ST	Q14134	TRIM29	P49137	MAPKAPK2	T158	A156V	156	Missense	proximal	-2	no	13.302	11.101	EPSD	TCGA;ICGC;COSMIC	11.681	Loss
CAMK_MAPKAPK_MK2_MAPKAPK2_ST	Q14134	TRIM29	P49137	MAPKAPK2	T158	S164F	164	Missense	distal	6	no	13.302	13.257	EPSD	TCGA;ICGC;COSMIC	11.681	Down-regulation
CAMK_MAPKAPK_MK2_MAPKAPK2_ST	Q14134	TRIM29	P49137	MAPKAPK2	S166	S164F	164	Missense	proximal	-2	no	19.687	14.261	EPSD	TCGA;ICGC;COSMIC	11.681	Down-regulation
CAMK_MAPKAPK_MK2_MAPKAPK2_ST	Q14134	TRIM29	P49137	MAPKAPK2	S168	D174N	174	Missense	distal	6	no	14.034	14.041	EPSD	TCGA;ICGC;COSMIC	11.681	Up-regulation
CAMK_MAPKAPK_MK2_MAPKAPK2_ST	Q14134	TRIM29	P49137	MAPKAPK2	S168	S164F	164	Missense	distal	-4	no	14.034	14.429	EPSD	TCGA;ICGC;COSMIC	11.681	Up-regulation
CAMK_MAPKAPK_MK2_MAPKAPK2_ST	Q14134	TRIM29	P49137	MAPKAPK2	S301	F302L	302	Missense	proximal	1	no	14.704	15.148	EPSD	TCGA;ICGC;COSMIC	11.681	Up-regulation
CAMK_MAPKAPK_MK2_MAPKAPK2_ST	Q14134	TRIM29	P49137	MAPKAPK2	S301	R298H	298	Missense	distal	-3	no	14.704	9.945	EPSD	TCGA;ICGC;COSMIC	11.681	Loss
CAMK_MAPKAPK_MK2_MAPKAPK2_ST	Q14134	TRIM29	P49137	MAPKAPK2	S472	Y474H	474	Missense	proximal	2	no	12.203	12.278	EPSD	TCGA;ICGC;COSMIC	11.681	Up-regulation
CAMK_MAPKAPK_MK2_MAPKAPK2_ST	Q14134	TRIM29	P49137	MAPKAPK2	S472	P465L	465	Missense	distal	-7	no	12.203	12.237	EPSD	TCGA;COSMIC	11.681	Up-regulation
CAMK_MAPKAPK_MK2_MAPKAPK2_ST	Q14134	TRIM29	P49137	MAPKAPK2	S472	R470I	470	Missense	proximal	-2	no	12.203	10.128	EPSD	TCGA	11.681	Loss
CAMK_MAPKAPK_MK2_MAPKAPK2_ST	Q14134	TRIM29	P49137	MAPKAPK2	S550	R549Q	549	Missense	proximal	-1	no	13.078	13.102	PhosphoSitePlus;EPSD	TCGA;ICGC;COSMIC	11.681	Up-regulation
CAMK_MAPKAPK_MK2_MAPKAPK2_ST	Q14134	TRIM29	P49137	MAPKAPK2	S550	P557L	557	Missense	distal	7	no	13.078	12.605	PhosphoSitePlus;EPSD	TCGA;COSMIC	11.681	Down-regulation
CAMK_MAPKAPK_MK2_MAPKAPK2_ST	Q14134	TRIM29	P49137	MAPKAPK2	S550	S552N	552	Missense	proximal	2	no	13.078	12.662	PhosphoSitePlus;EPSD	TCGA;COSMIC	11.681	Down-regulation
CAMK_MAPKAPK_MK2_MAPKAPK2_ST	Q14134	TRIM29	P49137	MAPKAPK2	S550	P545H	545	Missense	distal	-5	no	13.078	12.765	PhosphoSitePlus;EPSD	TCGA;ICGC;COSMIC	11.681	Down-regulation
CAMK_MAPKAPK_MK2_MAPKAPK2_ST	Q14134	TRIM29	P49137	MAPKAPK2	S552	R549Q	549	Missense	distal	-3	no	19.038	13.274	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	11.681	Down-regulation
CAMK_MAPKAPK_MK2_MAPKAPK2_ST	Q14134	TRIM29	P49137	MAPKAPK2	S552	P557L	557	Missense	distal	5	no	19.038	19.125	EPSD;PhosphoSitePlus	TCGA;COSMIC	11.681	Up-regulation
CAMK_MAPKAPK_MK2_MAPKAPK2_ST	Q14134	TRIM29	P49137	MAPKAPK2	S552	S552N	552	Missense	central	0	yes	19.038	0.000	EPSD;PhosphoSitePlus	TCGA;COSMIC	11.681	Loss
CAMK_MAPKAPK_MK2_MAPKAPK2_ST	Q14134	TRIM29	P49137	MAPKAPK2	S552	P545H	545	Missense	distal	-7	no	19.038	19.097	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	11.681	Up-regulation
CAMK_MAPKAPK_MK2_MAPKAPK2_ST	Q14134	TRIM29	P49137	MAPKAPK2	S584	G581R	581	Missense	distal	-3	no	1.613	12.272	EPSD	TCGA;COSMIC	11.681	Gain
CAMK_MAPKAPK_MK2_MAPKAPK2_ST	P09917	ALOX5	P49137	MAPKAPK2	T250	I246L	246	Missense	distal	-4	no	11.645	11.705	EPSD	TCGA;ICGC;COSMIC	11.681	Gain
CAMK_MAPKAPK_MK2_MAPKAPK2_ST	P09917	ALOX5	P49137	MAPKAPK2	S272	E274D	274	Missense	proximal	2	no	17.029	16.785	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	11.681	Down-regulation
CAMK_MAPKAPK_MK2_MAPKAPK2_ST	O95453	PARN	P49137	MAPKAPK2	S167	C169Y	169	Missense	proximal	2	no	12.562	12.271	EPSD	TCGA;COSMIC	11.681	Down-regulation
CAMK_MAPKAPK_MK2_MAPKAPK2_ST	O95453	PARN	P49137	MAPKAPK2	S167	T172A	172	Missense	distal	5	no	12.562	12.644	EPSD	TCGA;COSMIC	11.681	Up-regulation
CAMK_MAPKAPK_MK2_MAPKAPK2_ST	O95453	PARN	P49137	MAPKAPK2	S167	P174S	174	Missense	distal	7	no	12.562	12.445	EPSD	TCGA;COSMIC	11.681	Down-regulation
CAMK_MAPKAPK_MK2_MAPKAPK2_ST	O95453	PARN	P49137	MAPKAPK2	S167	T172M	172	Missense	distal	5	no	12.562	12.742	EPSD	TCGA;COSMIC	11.681	Up-regulation
CAMK_MAPKAPK_MK2_MAPKAPK2_ST	O95453	PARN	P49137	MAPKAPK2	S167	V162A	162	Missense	distal	-5	no	12.562	11.890	EPSD	TCGA;COSMIC	11.681	Down-regulation
CAMK_MAPKAPK_MK2_MAPKAPK2_ST	O95453	PARN	P49137	MAPKAPK2	T527	D529Y	529	Missense	proximal	2	no	12.253	12.015	EPSD	TCGA;COSMIC	11.681	Down-regulation
CAMK_MAPKAPK_MK2_MAPKAPK2_ST	O95453	PARN	P49137	MAPKAPK2	T527	T527I	527	Missense	central	0	yes	12.253	0.000	EPSD	TCGA;COSMIC	11.681	Loss
CAMK_MAPKAPK_MK2_MAPKAPK2_ST	O95453	PARN	P49137	MAPKAPK2	S557	R554H	554	Missense	distal	-3	no	16.300	11.540	PhosphoSitePlus	TCGA;COSMIC	11.681	Loss
CAMK_MAPKAPK_MK2_MAPKAPK2_ST	O95453	PARN	P49137	MAPKAPK2	S596	T594S	594	Missense	proximal	-2	no	11.258	13.012	EPSD	TCGA;COSMIC	11.681	Gain
CAMK_MAPKAPK_MK2_MAPKAPK2_ST	O95453	PARN	P49137	MAPKAPK2	S623	S625L	625	Missense	proximal	2	no	13.123	12.708	EPSD	TCGA;COSMIC	11.681	Down-regulation
CAMK_MAPKAPK_MK2_MAPKAPK2_ST	P17844	DDX5	P49137	MAPKAPK2	S198	C191G	191	Missense	distal	-7	no	13.931	13.944	PhosphoSitePlus	TCGA;ICGC;COSMIC	11.681	Up-regulation
CAMK_MAPKAPK_MK2_MAPKAPK2_ST	P17844	DDX5	P49137	MAPKAPK2	S198	R195H	195	Missense	distal	-3	no	13.931	9.171	PhosphoSitePlus	TCGA;ICGC;COSMIC;CCLE	11.681	Loss
CAMK_MAPKAPK_MK2_MAPKAPK2_ST	P17844	DDX5	P49137	MAPKAPK2	S279	D272N	272	Missense	distal	-7	no	11.872	11.882	EPSD	TCGA;ICGC;COSMIC	11.681	Up-regulation
CAMK_MAPKAPK_MK2_MAPKAPK2_ST	P17844	DDX5	P49137	MAPKAPK2	S279	T281S	281	Missense	proximal	2	no	11.872	11.849	EPSD	TCGA;ICGC;COSMIC	11.681	Down-regulation
CAMK_MAPKAPK_MK2_MAPKAPK2_ST	P17844	DDX5	P49137	MAPKAPK2	S422	P419R	419	Missense	distal	-3	no	9.493	14.158	EPSD	TCGA;ICGC;COSMIC	11.681	Gain
CAMK_MAPKAPK_MK2_MAPKAPK2_ST	P17844	DDX5	P49137	MAPKAPK2	S498	R496S	496	Missense	proximal	-2	no	9.502	11.769	EPSD	TCGA;ICGC	11.681	Gain
CAMK_MAPKAPK_MK2_MAPKAPK2_ST	P17844	DDX5	P49137	MAPKAPK2	S519	D525H	525	Missense	distal	6	no	13.223	13.221	EPSD	TCGA;ICGC;COSMIC	11.681	Down-regulation
CAMK_MAPKAPK_MK2_MAPKAPK2_ST	P17844	DDX5	P49137	MAPKAPK2	S519	F526C	526	Missense	distal	7	no	13.223	13.578	EPSD	TCGA;ICGC;COSMIC	11.681	Up-regulation
CAMK_MAPKAPK_MK2_MAPKAPK2_ST	Q13546	RIPK1	P49137	MAPKAPK2	S32	G29R	29	Missense	distal	-3	no	3.618	14.277	EPSD	TCGA;ICGC;COSMIC	11.681	Gain
CAMK_MAPKAPK_MK2_MAPKAPK2_ST	Q13546	RIPK1	P49137	MAPKAPK2	S320	R317T	317	Missense	distal	-3	no	17.125	11.250	PhosphoSitePlus	TCGA;ICGC;COSMIC	11.681	Loss
CAMK_MAPKAPK_MK2_MAPKAPK2_ST	Q13546	RIPK1	P49137	MAPKAPK2	S335	R332W	332	Missense	distal	-3	no	17.725	9.147	EPSD	TCGA;ICGC;COSMIC	11.681	Loss
CAMK_MAPKAPK_MK2_MAPKAPK2_ST	Q13546	RIPK1	P49137	MAPKAPK2	S335	T337I	337	Missense	proximal	2	no	17.725	17.285	EPSD	TCGA;ICGC;COSMIC	11.681	Down-regulation
CAMK_MAPKAPK_MK2_MAPKAPK2_ST	Q13546	RIPK1	P49137	MAPKAPK2	S416	E409D	409	Missense	distal	-7	no	14.768	14.808	EPSD	TCGA;ICGC;COSMIC	11.681	Up-regulation
CAMK_MAPKAPK_MK2_MAPKAPK2_ST	Q13546	RIPK1	P49137	MAPKAPK2	S416	R414M	414	Missense	proximal	-2	no	14.768	14.910	EPSD	TCGA;ICGC;COSMIC	11.681	Up-regulation
CAMK_MAPKAPK_MK2_MAPKAPK2_ST	Q13546	RIPK1	P49137	MAPKAPK2	S416	P419L	419	Missense	distal	3	no	14.768	14.659	EPSD	TCGA;ICGC;COSMIC	11.681	Down-regulation
CAMK_MAPKAPK_MK2_MAPKAPK2_ST	Q13546	RIPK1	P49137	MAPKAPK2	S416	S416F	416	Missense	central	0	yes	14.768	0.000	EPSD	TCGA;ICGC	11.681	Loss
CAMK_MAPKAPK_MK2_MAPKAPK2_ST	P11831	SRF	P49137	MAPKAPK2	S237	E242K	242	Missense	distal	5	no	11.669	11.882	EPSD	TCGA;COSMIC	11.681	Gain
CAMK_MAPKAPK_MK2_MAPKAPK2_ST	P11831	SRF	P49137	MAPKAPK2	S251	T244R	244	Missense	distal	-7	no	12.468	12.464	EPSD	TCGA;COSMIC	11.681	Down-regulation
CAMK_MAPKAPK_MK2_MAPKAPK2_ST	P11831	SRF	P49137	MAPKAPK2	S251	E252K	252	Missense	proximal	1	no	12.468	12.004	EPSD	TCGA;COSMIC	11.681	Down-regulation
CAMK_MAPKAPK_MK2_MAPKAPK2_ST	P11831	SRF	P49137	MAPKAPK2	S251	L246F	246	Missense	distal	-5	no	12.468	11.771	EPSD	TCGA;ICGC;COSMIC	11.681	Down-regulation
CAMK_MAPKAPK_MK2_MAPKAPK2_ST	P11831	SRF	P49137	MAPKAPK2	S251	D245N	245	Missense	distal	-6	no	12.468	12.476	EPSD	TCGA;COSMIC	11.681	Up-regulation
CAMK_MAPKAPK_MK2_MAPKAPK2_ST	P11831	SRF	P49137	MAPKAPK2	S251	D245Y	245	Missense	distal	-6	no	12.468	12.507	EPSD	TCGA;ICGC;COSMIC	11.681	Up-regulation
CAMK_MAPKAPK_MK2_MAPKAPK2_ST	P11831	SRF	P49137	MAPKAPK2	S313	V310I	310	Missense	distal	-3	no	9.632	12.071	EPSD	TCGA;ICGC;COSMIC	11.681	Gain
CAMK_MAPKAPK_MK2_MAPKAPK2_ST	Q13263	TRIM28	P49137	MAPKAPK2	S285	S279N	279	Missense	distal	-6	no	16.286	16.358	EPSD	TCGA;COSMIC	11.681	Up-regulation
CAMK_MAPKAPK_MK2_MAPKAPK2_ST	Q13263	TRIM28	P49137	MAPKAPK2	S285	V287I	287	Missense	proximal	2	no	16.286	16.203	EPSD	TCGA;ICGC;COSMIC	11.681	Down-regulation
CAMK_MAPKAPK_MK2_MAPKAPK2_ST	Q13263	TRIM28	P49137	MAPKAPK2	S285	Q288R	288	Missense	distal	3	no	16.286	16.382	EPSD	TCGA;ICGC;COSMIC	11.681	Up-regulation
CAMK_MAPKAPK_MK2_MAPKAPK2_ST	Q13263	TRIM28	P49137	MAPKAPK2	S437	S437C	437	Missense	central	0	yes	11.763	0.000	EPSD	TCGA;ICGC;COSMIC	11.681	Loss
CAMK_MAPKAPK_MK2_MAPKAPK2_ST	Q13263	TRIM28	P49137	MAPKAPK2	S437	S439R	439	Missense	proximal	2	no	11.763	11.659	EPSD	TCGA;COSMIC	11.681	Loss
CAMK_MAPKAPK_MK2_MAPKAPK2_ST	Q13263	TRIM28	P49137	MAPKAPK2	S437	M443I	443	Missense	distal	6	no	11.763	11.755	EPSD	TCGA;ICGC;COSMIC	11.681	Down-regulation
CAMK_MAPKAPK_MK2_MAPKAPK2_ST	Q13263	TRIM28	P49137	MAPKAPK2	S473	G480S	480	Missense	distal	7	no	19.200	19.405	PhosphoSitePlus	TCGA;ICGC	11.681	Up-regulation
CAMK_MAPKAPK_MK2_MAPKAPK2_ST	Q13263	TRIM28	P49137	MAPKAPK2	S473	R472H	472	Missense	proximal	-1	no	19.200	19.222	PhosphoSitePlus	TCGA;COSMIC	11.681	Up-regulation
CAMK_MAPKAPK_MK2_MAPKAPK2_ST	Q13263	TRIM28	P49137	MAPKAPK2	S489	D496N	496	Missense	distal	7	no	13.101	12.923	EPSD	TCGA;ICGC	11.681	Down-regulation
CAMK_MAPKAPK_MK2_MAPKAPK2_ST	Q13263	TRIM28	P49137	MAPKAPK2	S489	E491D	491	Missense	proximal	2	no	13.101	12.857	EPSD	TCGA;COSMIC	11.681	Down-regulation
CAMK_MAPKAPK_MK2_MAPKAPK2_ST	Q13263	TRIM28	P49137	MAPKAPK2	S489	R492C	492	Missense	distal	3	no	13.101	13.051	EPSD	TCGA;ICGC;COSMIC;GDSC;CCLE	11.681	Down-regulation
CAMK_MAPKAPK_MK2_MAPKAPK2_ST	Q13263	TRIM28	P49137	MAPKAPK2	S489	R483H	483	Missense	distal	-6	no	13.101	13.165	EPSD	TCGA;ICGC;COSMIC	11.681	Up-regulation
CAMK_MAPKAPK_MK2_MAPKAPK2_ST	Q13263	TRIM28	P49137	MAPKAPK2	S501	D496N	496	Missense	distal	-5	no	12.041	12.119	EPSD	TCGA;ICGC	11.681	Up-regulation
CAMK_MAPKAPK_MK2_MAPKAPK2_ST	Q13263	TRIM28	P49137	MAPKAPK2	S501	V508L	508	Missense	distal	7	no	12.041	11.908	EPSD	TCGA;ICGC;COSMIC	11.681	Down-regulation
CAMK_MAPKAPK_MK2_MAPKAPK2_ST	Q13263	TRIM28	P49137	MAPKAPK2	S501	V508D	508	Missense	distal	7	no	12.041	12.152	EPSD	TCGA	11.681	Up-regulation
CAMK_MAPKAPK_MK2_MAPKAPK2_ST	Q13263	TRIM28	P49137	MAPKAPK2	S594	P590S	590	Missense	distal	-4	no	14.830	14.751	EPSD	TCGA;ICGC;COSMIC	11.681	Down-regulation
CAMK_MAPKAPK_MK2_MAPKAPK2_ST	Q13263	TRIM28	P49137	MAPKAPK2	S594	A587V	587	Missense	distal	-7	no	14.830	14.874	EPSD	TCGA;ICGC;COSMIC	11.681	Up-regulation
CAMK_MAPKAPK_MK2_MAPKAPK2_ST	Q13263	TRIM28	P49137	MAPKAPK2	S594	S598G	598	Missense	distal	4	no	14.830	14.642	EPSD	TCGA	11.681	Down-regulation
CAMK_MAPKAPK_MK2_MAPKAPK2_ST	Q13263	TRIM28	P49137	MAPKAPK2	S594	R591H	591	Missense	distal	-3	no	14.830	10.071	EPSD	TCGA;ICGC	11.681	Loss
CAMK_MAPKAPK_MK2_MAPKAPK2_ST	Q13263	TRIM28	P49137	MAPKAPK2	S598	S598G	598	Missense	central	0	yes	14.103	0.000	EPSD	TCGA	11.681	Loss
CAMK_MAPKAPK_MK2_MAPKAPK2_ST	Q13263	TRIM28	P49137	MAPKAPK2	S598	R591H	591	Missense	distal	-7	no	14.103	14.194	EPSD	TCGA;ICGC	11.681	Up-regulation
CAMK_MAPKAPK_MK2_MAPKAPK2_ST	P33241	LSP1	P49137	MAPKAPK2	S252	E254K	254	Missense	proximal	2	no	19.119	18.821	PhosphoSitePlus	TCGA;COSMIC;CCLE	11.681	Down-regulation
CAMK_MAPKAPK_MK2_MAPKAPK2_ST	P33241	LSP1	P49137	MAPKAPK2	S257	E254K	254	Missense	distal	-3	no	12.185	12.356	EPSD	TCGA;COSMIC;CCLE	11.681	Up-regulation
CAMK_MAPKAPK_MK2_MAPKAPK2_ST	P33241	LSP1	P49137	MAPKAPK2	S265	E271K	271	Missense	distal	6	no	12.598	12.583	EPSD	TCGA;COSMIC	11.681	Down-regulation
CAMK_MAPKAPK_MK2_MAPKAPK2_ST	P33241	LSP1	P49137	MAPKAPK2	S276	E271K	271	Missense	distal	-5	no	13.318	12.711	EPSD	TCGA;COSMIC	11.681	Down-regulation
CAMK_MAPKAPK_MK2_MAPKAPK2_ST	O75925	PIAS1	P49137	MAPKAPK2	S289	L294F	294	Missense	distal	5	no	12.924	13.142	EPSD	TCGA;ICGC;COSMIC	11.681	Up-regulation
CAMK_MAPKAPK_MK2_MAPKAPK2_ST	O75925	PIAS1	P49137	MAPKAPK2	S322	P320S	320	Missense	proximal	-2	no	8.753	11.985	EPSD	TCGA;ICGC;COSMIC	11.681	Gain
CAMK_MAPKAPK_MK2_MAPKAPK2_ST	O75925	PIAS1	P49137	MAPKAPK2	S451	A445V	445	Missense	distal	-6	no	12.877	12.906	EPSD	TCGA;ICGC;COSMIC	11.681	Up-regulation
CAMK_MAPKAPK_MK2_MAPKAPK2_ST	O75925	PIAS1	P49137	MAPKAPK2	S451	K456E	456	Missense	distal	5	no	12.877	12.663	EPSD	TCGA;ICGC;COSMIC	11.681	Down-regulation
CAMK_MAPKAPK_MK2_MAPKAPK2_ST	O75925	PIAS1	P49137	MAPKAPK2	S451	V444L	444	Missense	distal	-7	no	12.877	12.874	EPSD	TCGA;ICGC;COSMIC	11.681	Down-regulation
CAMK_MAPKAPK_MK2_MAPKAPK2_ST	O75925	PIAS1	P49137	MAPKAPK2	S468	E473D	473	Missense	distal	5	no	13.034	13.215	EPSD	TCGA;ICGC;COSMIC	11.681	Up-regulation
CAMK_MAPKAPK_MK2_MAPKAPK2_ST	O75925	PIAS1	P49137	MAPKAPK2	S468	P475S	475	Missense	distal	7	no	13.034	12.917	EPSD	TCGA;ICGC;COSMIC	11.681	Down-regulation
CAMK_MAPKAPK_MK2_MAPKAPK2_ST	O75925	PIAS1	P49137	MAPKAPK2	S485	P486S	486	Missense	proximal	1	no	14.895	14.785	EPSD	TCGA;ICGC;COSMIC	11.681	Down-regulation
CAMK_MAPKAPK_MK2_MAPKAPK2_ST	O75925	PIAS1	P49137	MAPKAPK2	S485	N491H	491	Missense	distal	6	no	14.895	14.885	EPSD	TCGA;ICGC;COSMIC	11.681	Down-regulation
CAMK_MAPKAPK_MK2_MAPKAPK2_ST	O75925	PIAS1	P49137	MAPKAPK2	T487	P486S	486	Missense	proximal	-1	no	11.846	11.845	EPSD	TCGA;ICGC;COSMIC	11.681	Down-regulation
CAMK_MAPKAPK_MK2_MAPKAPK2_ST	O75925	PIAS1	P49137	MAPKAPK2	T487	G494S	494	Missense	distal	7	no	11.846	12.051	EPSD	TCGA;ICGC;COSMIC	11.681	Up-regulation
CAMK_MAPKAPK_MK2_MAPKAPK2_ST	O75925	PIAS1	P49137	MAPKAPK2	T487	N491H	491	Missense	distal	4	no	11.846	11.737	EPSD	TCGA;ICGC;COSMIC	11.681	Down-regulation
CAMK_MAPKAPK_MK2_MAPKAPK2_ST	O75925	PIAS1	P49137	MAPKAPK2	S488	P486S	486	Missense	proximal	-2	no	9.957	13.189	EPSD	TCGA;ICGC;COSMIC	11.681	Gain
CAMK_MAPKAPK_MK2_MAPKAPK2_ST	O75925	PIAS1	P49137	MAPKAPK2	S503	S510R	510	Missense	distal	7	no	11.873	11.902	EPSD	TCGA;ICGC	11.681	Up-regulation
CAMK_MAPKAPK_MK2_MAPKAPK2_ST	O75925	PIAS1	P49137	MAPKAPK2	S503	P504L	504	Missense	proximal	1	no	11.873	11.964	EPSD	TCGA;ICGC;COSMIC	11.681	Up-regulation
CAMK_MAPKAPK_MK2_MAPKAPK2_ST	O75925	PIAS1	P49137	MAPKAPK2	S503	P499S	499	Missense	distal	-4	no	11.873	11.794	EPSD	TCGA;ICGC;COSMIC	11.681	Down-regulation
CAMK_MAPKAPK_MK2_MAPKAPK2_ST	O75925	PIAS1	P49137	MAPKAPK2	S510	S510R	510	Missense	central	0	yes	17.412	0.000	EPSD	TCGA;ICGC	11.681	Loss
CAMK_MAPKAPK_MK2_MAPKAPK2_ST	O75925	PIAS1	P49137	MAPKAPK2	S510	P504L	504	Missense	distal	-6	no	17.412	17.443	EPSD	TCGA;ICGC;COSMIC	11.681	Up-regulation
CAMK_MAPKAPK_MK2_MAPKAPK2_ST	O75925	PIAS1	P49137	MAPKAPK2	S522	T521P	521	Missense	proximal	-1	no	12.530	12.535	PhosphoSitePlus	TCGA	11.681	Up-regulation
CAMK_MAPKAPK_MK2_MAPKAPK2_ST	O75925	PIAS1	P49137	MAPKAPK2	S522	Y518H	518	Missense	distal	-4	no	12.530	12.437	PhosphoSitePlus	TCGA;ICGC;COSMIC	11.681	Down-regulation
CAMK_MAPKAPK_MK2_MAPKAPK2_ST	Q9NY61	AATF	P49137	MAPKAPK2	S20	R18G	18	Missense	proximal	-2	no	13.145	12.075	EPSD	TCGA;ICGC	11.681	Down-regulation
CAMK_MAPKAPK_MK2_MAPKAPK2_ST	Q9NY61	AATF	P49137	MAPKAPK2	S141	P147S	147	Missense	distal	6	no	14.027	14.044	EPSD	TCGA;ICGC	11.681	Up-regulation
CAMK_MAPKAPK_MK2_MAPKAPK2_ST	Q9NY61	AATF	P49137	MAPKAPK2	S143	P147S	147	Missense	distal	4	no	19.058	19.117	EPSD	TCGA;ICGC	11.681	Up-regulation
CAMK_MAPKAPK_MK2_MAPKAPK2_ST	Q9NY61	AATF	P49137	MAPKAPK2	S143	F149S	149	Missense	distal	6	no	19.058	19.103	EPSD	TCGA;ICGC	11.681	Up-regulation
CAMK_MAPKAPK_MK2_MAPKAPK2_ST	Q9NY61	AATF	P49137	MAPKAPK2	S155	E158D	158	Missense	distal	3	no	14.094	14.001	EPSD	TCGA;ICGC	11.681	Down-regulation
CAMK_MAPKAPK_MK2_MAPKAPK2_ST	Q9NY61	AATF	P49137	MAPKAPK2	S155	S153N	153	Missense	proximal	-2	no	14.094	11.730	EPSD	TCGA;ICGC	11.681	Down-regulation
CAMK_MAPKAPK_MK2_MAPKAPK2_ST	Q9NY61	AATF	P49137	MAPKAPK2	S155	F149S	149	Missense	distal	-6	no	14.094	13.986	EPSD	TCGA;ICGC	11.681	Down-regulation
CAMK_MAPKAPK_MK2_MAPKAPK2_ST	Q9NY61	AATF	P49137	MAPKAPK2	T366	H371R	371	Missense	distal	5	no	12.539	12.233	PhosphoSitePlus	TCGA;ICGC	11.681	Down-regulation
CAMK_MAPKAPK_MK2_MAPKAPK2_ST	Q9NY61	AATF	P49137	MAPKAPK2	T366	R365H	365	Missense	proximal	-1	no	12.539	12.561	PhosphoSitePlus	TCGA;ICGC	11.681	Up-regulation
CAMK_MAPKAPK_MK2_MAPKAPK2_ST	Q9NY61	AATF	P49137	MAPKAPK2	T412	R405S	405	Missense	distal	-7	no	13.095	13.130	EPSD	TCGA;ICGC	11.681	Up-regulation
CAMK_MAPKAPK_MK2_MAPKAPK2_ST	Q9NY61	AATF	P49137	MAPKAPK2	T412	R414H	414	Missense	proximal	2	no	13.095	12.585	EPSD	TCGA;ICGC	11.681	Down-regulation
CAMK_MAPKAPK_MK2_MAPKAPK2_ST	Q9NY61	AATF	P49137	MAPKAPK2	T412	R418Q	418	Missense	distal	6	no	13.095	13.075	EPSD	TCGA;ICGC;CCLE	11.681	Down-regulation
CAMK_MAPKAPK_MK2_MAPKAPK2_ST	Q9NY61	AATF	P49137	MAPKAPK2	T412	R408Q	408	Missense	distal	-4	no	13.095	13.285	EPSD	TCGA;ICGC	11.681	Up-regulation
CAMK_MAPKAPK_MK2_MAPKAPK2_ST	Q9NY61	AATF	P49137	MAPKAPK2	S477	S478F	478	Missense	proximal	1	no	13.480	13.238	EPSD	TCGA;ICGC	11.681	Down-regulation
CAMK_MAPKAPK_MK2_MAPKAPK2_ST	Q9NY61	AATF	P49137	MAPKAPK2	S477	I472M	472	Missense	distal	-5	no	13.480	12.913	EPSD	TCGA;ICGC	11.681	Down-regulation
CAMK_MAPKAPK_MK2_MAPKAPK2_ST	Q9NY61	AATF	P49137	MAPKAPK2	S477	R474W	474	Missense	distal	-3	no	13.480	4.901	EPSD	TCGA;ICGC	11.681	Loss
CAMK_MAPKAPK_MK2_MAPKAPK2_ST	Q9NY61	AATF	P49137	MAPKAPK2	S510	R516W	516	Missense	distal	6	no	13.918	13.893	EPSD	TCGA;ICGC	11.681	Down-regulation
CAMK_MAPKAPK_MK2_MAPKAPK2_ST	Q00613	HSF1	P49137	MAPKAPK2	S123	E128K	128	Missense	distal	5	no	11.501	11.714	EPSD	TCGA;COSMIC	11.681	Gain
CAMK_MAPKAPK_MK2_MAPKAPK2_ST	Q00613	HSF1	P49137	MAPKAPK2	S136	R133H	133	Missense	distal	-3	no	17.499	12.740	EPSD	TCGA;COSMIC	11.681	Down-regulation
CAMK_MAPKAPK_MK2_MAPKAPK2_ST	Q00613	HSF1	P49137	MAPKAPK2	S136	I130V	130	Missense	distal	-6	no	17.499	17.505	EPSD	TCGA;COSMIC	11.681	Up-regulation
CAMK_MAPKAPK_MK2_MAPKAPK2_ST	Q00613	HSF1	P49137	MAPKAPK2	S216	S221Y	221	Missense	distal	5	no	11.426	11.850	EPSD	TCGA;COSMIC	11.681	Gain
CAMK_MAPKAPK_MK2_MAPKAPK2_ST	Q00613	HSF1	P49137	MAPKAPK2	S218	S221Y	221	Missense	distal	3	no	12.045	11.795	EPSD	TCGA;COSMIC	11.681	Down-regulation
CAMK_MAPKAPK_MK2_MAPKAPK2_ST	Q00613	HSF1	P49137	MAPKAPK2	S248	S250C	250	Missense	proximal	2	no	12.237	11.837	EPSD	TCGA;COSMIC	11.681	Down-regulation
CAMK_MAPKAPK_MK2_MAPKAPK2_ST	Q00613	HSF1	P49137	MAPKAPK2	S248	A254T	254	Missense	distal	6	no	12.237	12.245	EPSD	TCGA;COSMIC;CCLE	11.681	Up-regulation
CAMK_MAPKAPK_MK2_MAPKAPK2_ST	Q00613	HSF1	P49137	MAPKAPK2	S250	S250C	250	Missense	central	0	yes	13.284	0.000	EPSD	TCGA;COSMIC	11.681	Loss
CAMK_MAPKAPK_MK2_MAPKAPK2_ST	Q00613	HSF1	P49137	MAPKAPK2	S250	A254T	254	Missense	distal	4	no	13.284	13.310	EPSD	TCGA;COSMIC;CCLE	11.681	Up-regulation
CAMK_MAPKAPK_MK2_MAPKAPK2_ST	Q00613	HSF1	P49137	MAPKAPK2	S251	S250C	250	Missense	proximal	-1	no	13.186	13.196	EPSD	TCGA;COSMIC	11.681	Up-regulation
CAMK_MAPKAPK_MK2_MAPKAPK2_ST	Q00613	HSF1	P49137	MAPKAPK2	S251	A254T	254	Missense	distal	3	no	13.186	13.213	EPSD	TCGA;COSMIC;CCLE	11.681	Up-regulation
CAMK_MAPKAPK_MK2_MAPKAPK2_ST	Q00613	HSF1	P49137	MAPKAPK2	S279	P276L	276	Missense	distal	-3	no	11.909	11.483	EPSD	TCGA;COSMIC	11.681	Loss
CAMK_MAPKAPK_MK2_MAPKAPK2_ST	Q00613	HSF1	P49137	MAPKAPK2	S279	E286K	286	Missense	distal	7	no	11.909	11.636	EPSD	TCGA;COSMIC	11.681	Loss
CAMK_MAPKAPK_MK2_MAPKAPK2_ST	Q00613	HSF1	P49137	MAPKAPK2	S279	M277V	277	Missense	proximal	-2	no	11.909	10.239	EPSD	TCGA;COSMIC	11.681	Loss
CAMK_MAPKAPK_MK2_MAPKAPK2_ST	Q00613	HSF1	P49137	MAPKAPK2	S290	R296C	296	Missense	distal	6	no	15.437	15.412	EPSD	TCGA;COSMIC	11.681	Down-regulation
CAMK_MAPKAPK_MK2_MAPKAPK2_ST	Q00613	HSF1	P49137	MAPKAPK2	S290	P288L	288	Missense	proximal	-2	no	15.437	15.311	EPSD	TCGA;COSMIC	11.681	Down-regulation
CAMK_MAPKAPK_MK2_MAPKAPK2_ST	Q00613	HSF1	P49137	MAPKAPK2	S290	E286K	286	Missense	distal	-4	no	15.437	15.604	EPSD	TCGA;COSMIC	11.681	Up-regulation
CAMK_MAPKAPK_MK2_MAPKAPK2_ST	Q00613	HSF1	P49137	MAPKAPK2	S292	R296C	296	Missense	distal	4	no	15.145	15.032	EPSD	TCGA;COSMIC	11.681	Down-regulation
CAMK_MAPKAPK_MK2_MAPKAPK2_ST	Q00613	HSF1	P49137	MAPKAPK2	S292	P288L	288	Missense	distal	-4	no	15.145	15.269	EPSD	TCGA;COSMIC	11.681	Up-regulation
CAMK_MAPKAPK_MK2_MAPKAPK2_ST	Q00613	HSF1	P49137	MAPKAPK2	S292	E286K	286	Missense	distal	-6	no	15.145	15.208	EPSD	TCGA;COSMIC	11.681	Up-regulation
CAMK_MAPKAPK_MK2_MAPKAPK2_ST	Q00613	HSF1	P49137	MAPKAPK2	S307	E300Q	300	Missense	distal	-7	no	12.426	12.477	EPSD	TCGA	11.681	Up-regulation
CAMK_MAPKAPK_MK2_MAPKAPK2_ST	Q00613	HSF1	P49137	MAPKAPK2	S320	R317H	317	Missense	distal	-3	no	17.071	12.312	EPSD	TCGA;COSMIC	11.681	Down-regulation
CAMK_MAPKAPK_MK2_MAPKAPK2_ST	Q00613	HSF1	P49137	MAPKAPK2	S320	T323I	323	Missense	distal	3	no	17.071	16.889	EPSD	TCGA;COSMIC	11.681	Down-regulation
CAMK_MAPKAPK_MK2_MAPKAPK2_ST	Q00613	HSF1	P49137	MAPKAPK2	S320	S320F	320	Missense	central	0	yes	17.071	0.000	EPSD	TCGA;COSMIC	11.681	Loss
CAMK_MAPKAPK_MK2_MAPKAPK2_ST	Q00613	HSF1	P49137	MAPKAPK2	S320	P327L	327	Missense	distal	7	no	17.071	16.597	EPSD	TCGA	11.681	Down-regulation
CAMK_MAPKAPK_MK2_MAPKAPK2_ST	Q00613	HSF1	P49137	MAPKAPK2	S326	D332Y	332	Missense	distal	6	no	12.640	12.630	EPSD	TCGA;COSMIC	11.681	Down-regulation
CAMK_MAPKAPK_MK2_MAPKAPK2_ST	Q00613	HSF1	P49137	MAPKAPK2	S326	T323I	323	Missense	distal	-3	no	12.640	13.226	EPSD	TCGA;COSMIC	11.681	Up-regulation
CAMK_MAPKAPK_MK2_MAPKAPK2_ST	Q00613	HSF1	P49137	MAPKAPK2	S326	S320F	320	Missense	distal	-6	no	12.640	12.748	EPSD	TCGA;COSMIC	11.681	Up-regulation
CAMK_MAPKAPK_MK2_MAPKAPK2_ST	Q00613	HSF1	P49137	MAPKAPK2	S326	A329T	329	Missense	distal	3	no	12.640	12.668	EPSD	TCGA;COSMIC	11.681	Up-regulation
CAMK_MAPKAPK_MK2_MAPKAPK2_ST	Q00613	HSF1	P49137	MAPKAPK2	S326	S333F	333	Missense	distal	7	no	12.640	12.060	EPSD	TCGA;COSMIC	11.681	Down-regulation
CAMK_MAPKAPK_MK2_MAPKAPK2_ST	Q00613	HSF1	P49137	MAPKAPK2	S326	P327L	327	Missense	proximal	1	no	12.640	12.731	EPSD	TCGA	11.681	Up-regulation
CAMK_MAPKAPK_MK2_MAPKAPK2_ST	Q00613	HSF1	P49137	MAPKAPK2	S338	D332Y	332	Missense	distal	-6	no	12.439	12.477	EPSD	TCGA;COSMIC	11.681	Up-regulation
CAMK_MAPKAPK_MK2_MAPKAPK2_ST	Q00613	HSF1	P49137	MAPKAPK2	S338	E339G	339	Missense	proximal	1	no	12.439	11.936	EPSD	TCGA;COSMIC	11.681	Down-regulation
CAMK_MAPKAPK_MK2_MAPKAPK2_ST	Q00613	HSF1	P49137	MAPKAPK2	S338	S333F	333	Missense	distal	-5	no	12.439	12.236	EPSD	TCGA;COSMIC	11.681	Down-regulation
CAMK_MAPKAPK_MK2_MAPKAPK2_ST	Q00613	HSF1	P49137	MAPKAPK2	T355	A351T	351	Missense	distal	-4	no	13.826	13.701	EPSD	TCGA;COSMIC	11.681	Down-regulation
CAMK_MAPKAPK_MK2_MAPKAPK2_ST	Q00613	HSF1	P49137	MAPKAPK2	S363	P364S	364	Missense	proximal	1	no	18.111	18.000	EPSD	TCGA;COSMIC	11.681	Down-regulation
CAMK_MAPKAPK_MK2_MAPKAPK2_ST	Q00613	HSF1	P49137	MAPKAPK2	S458	E453K	453	Missense	distal	-5	no	12.274	11.667	EPSD	TCGA;COSMIC	11.681	Loss
CAMK_MAPKAPK_MK2_MAPKAPK2_ST	Q00613	HSF1	P49137	MAPKAPK2	S513	A507V	507	Missense	distal	-6	no	12.325	12.354	EPSD	TCGA;ICGC;COSMIC	11.681	Up-regulation
CAMK_MAPKAPK_MK2_MAPKAPK2_ST	Q07817	BCL2L1	P49137	MAPKAPK2	S49	A50V	50	Missense	proximal	1	no	13.185	13.435	EPSD	TCGA;ICGC;COSMIC	11.681	Up-regulation
CAMK_MAPKAPK_MK2_MAPKAPK2_ST	Q07817	BCL2L1	P49137	MAPKAPK2	S62	A64V	64	Missense	proximal	2	no	12.896	12.591	PhosphoSitePlus	TCGA	11.681	Down-regulation
CAMK_MAPKAPK_MK2_MAPKAPK2_ST	Q16875	PFKFB3	P49137	MAPKAPK2	S211	R208G	208	Missense	distal	-3	no	14.175	3.515	EPSD	TCGA;COSMIC	11.681	Loss
CAMK_MAPKAPK_MK2_MAPKAPK2_ST	Q16875	PFKFB3	P49137	MAPKAPK2	S211	V218M	218	Missense	distal	7	no	14.175	14.253	EPSD	TCGA;ICGC;COSMIC	11.681	Up-regulation
CAMK_MAPKAPK_MK2_MAPKAPK2_ST	Q16875	PFKFB3	P49137	MAPKAPK2	S446	R443W	443	Missense	distal	-3	no	16.027	7.448	EPSD	TCGA;ICGC;COSMIC;CCLE	11.681	Loss
CAMK_MAPKAPK_MK2_MAPKAPK2_ST	Q16875	PFKFB3	P49137	MAPKAPK2	S461	S461C	461	Missense	central	0	yes	18.167	0.000	PhosphoSitePlus	TCGA;COSMIC	11.681	Loss
CAMK_MAPKAPK_MK2_MAPKAPK2_ST	Q16875	PFKFB3	P49137	MAPKAPK2	S461	P464L	464	Missense	distal	3	no	18.167	18.058	PhosphoSitePlus	TCGA;COSMIC	11.681	Down-regulation
CAMK_MAPKAPK_MK2_MAPKAPK2_ST	Q16875	PFKFB3	P49137	MAPKAPK2	S461	N460Y	460	Missense	proximal	-1	no	18.167	18.171	PhosphoSitePlus	TCGA;COSMIC	11.681	Up-regulation
CAMK_MAPKAPK_MK2_MAPKAPK2_ST	Q16875	PFKFB3	P49137	MAPKAPK2	S478	R475G	475	Missense	distal	-3	no	15.214	4.555	EPSD	TCGA;COSMIC	11.681	Loss
CAMK_MAPKAPK_MK2_MAPKAPK2_ST	P49815	TSC2	P49137	MAPKAPK2	S188	K185R	185	Missense	distal	-3	no	7.755	12.879	EPSD	TCGA;ICGC	11.681	Gain
CAMK_MAPKAPK_MK2_MAPKAPK2_ST	P49815	TSC2	P49137	MAPKAPK2	S311	S311F	311	Missense	central	0	yes	14.604	0.000	EPSD	TCGA;ICGC;COSMIC	11.681	Loss
CAMK_MAPKAPK_MK2_MAPKAPK2_ST	P49815	TSC2	P49137	MAPKAPK2	S540	R537H	537	Missense	distal	-3	no	19.462	14.703	EPSD	TCGA;ICGC;COSMIC	11.681	Down-regulation
CAMK_MAPKAPK_MK2_MAPKAPK2_ST	P49815	TSC2	P49137	MAPKAPK2	S609	A607V	607	Missense	proximal	-2	no	12.074	9.874	EPSD	TCGA;ICGC	11.681	Loss
CAMK_MAPKAPK_MK2_MAPKAPK2_ST	P49815	TSC2	P49137	MAPKAPK2	S660	K657R	657	Missense	distal	-3	no	7.985	13.109	EPSD	TCGA;ICGC;COSMIC	11.681	Gain
CAMK_MAPKAPK_MK2_MAPKAPK2_ST	P49815	TSC2	P49137	MAPKAPK2	S937	R943K	943	Missense	distal	6	no	18.542	18.514	EPSD	TCGA;ICGC;COSMIC	11.681	Down-regulation
CAMK_MAPKAPK_MK2_MAPKAPK2_ST	P49815	TSC2	P49137	MAPKAPK2	S937	R934S	934	Missense	distal	-3	no	18.542	12.213	EPSD	TCGA;ICGC;COSMIC	11.681	Down-regulation
CAMK_MAPKAPK_MK2_MAPKAPK2_ST	P49815	TSC2	P49137	MAPKAPK2	S939	R943K	943	Missense	distal	4	no	19.644	19.469	EPSD	TCGA;ICGC;COSMIC	11.681	Down-regulation
CAMK_MAPKAPK_MK2_MAPKAPK2_ST	P49815	TSC2	P49137	MAPKAPK2	S939	R934S	934	Missense	distal	-5	no	19.644	19.491	EPSD	TCGA;ICGC;COSMIC	11.681	Down-regulation
CAMK_MAPKAPK_MK2_MAPKAPK2_ST	P49815	TSC2	P49137	MAPKAPK2	S946	R943K	943	Missense	distal	-3	no	16.852	11.728	EPSD	TCGA;ICGC;COSMIC	11.681	Down-regulation
CAMK_MAPKAPK_MK2_MAPKAPK2_ST	P49815	TSC2	P49137	MAPKAPK2	S979	R978H	978	Missense	proximal	-1	no	16.711	16.733	EPSD	TCGA;ICGC;COSMIC	11.681	Up-regulation
CAMK_MAPKAPK_MK2_MAPKAPK2_ST	P49815	TSC2	P49137	MAPKAPK2	S981	R978H	978	Missense	distal	-3	no	21.035	16.276	EPSD	TCGA;ICGC;COSMIC	11.681	Down-regulation
CAMK_MAPKAPK_MK2_MAPKAPK2_ST	P49815	TSC2	P49137	MAPKAPK2	S983	R978H	978	Missense	distal	-5	no	12.332	11.855	EPSD	TCGA;ICGC;COSMIC	11.681	Down-regulation
CAMK_MAPKAPK_MK2_MAPKAPK2_ST	P49815	TSC2	P49137	MAPKAPK2	S999	D1004N	1004	Missense	distal	5	no	13.470	13.436	EPSD	TCGA;COSMIC	11.681	Down-regulation
CAMK_MAPKAPK_MK2_MAPKAPK2_ST	P49815	TSC2	P49137	MAPKAPK2	S999	G1001V	1001	Missense	proximal	2	no	13.470	13.570	EPSD	TCGA;COSMIC	11.681	Up-regulation
CAMK_MAPKAPK_MK2_MAPKAPK2_ST	P49815	TSC2	P49137	MAPKAPK2	S1096	P1098L	1098	Missense	proximal	2	no	13.090	12.867	EPSD	TCGA;COSMIC	11.681	Down-regulation
CAMK_MAPKAPK_MK2_MAPKAPK2_ST	P49815	TSC2	P49137	MAPKAPK2	S1096	G1091S	1091	Missense	distal	-5	no	13.090	13.969	EPSD	TCGA;COSMIC	11.681	Up-regulation
CAMK_MAPKAPK_MK2_MAPKAPK2_ST	P49815	TSC2	P49137	MAPKAPK2	S1121	R1127Q	1127	Missense	distal	6	no	11.737	11.717	EPSD	TCGA	11.681	Down-regulation
CAMK_MAPKAPK_MK2_MAPKAPK2_ST	P49815	TSC2	P49137	MAPKAPK2	S1130	L1137F	1137	Missense	distal	7	no	16.204	15.981	EPSD	TCGA;COSMIC	11.681	Down-regulation
CAMK_MAPKAPK_MK2_MAPKAPK2_ST	P49815	TSC2	P49137	MAPKAPK2	S1130	R1127Q	1127	Missense	distal	-3	no	16.204	10.440	EPSD	TCGA	11.681	Loss
CAMK_MAPKAPK_MK2_MAPKAPK2_ST	P49815	TSC2	P49137	MAPKAPK2	S1132	L1137F	1137	Missense	distal	5	no	18.682	18.901	EPSD	TCGA;COSMIC	11.681	Up-regulation
CAMK_MAPKAPK_MK2_MAPKAPK2_ST	P49815	TSC2	P49137	MAPKAPK2	S1132	R1127Q	1127	Missense	distal	-5	no	18.682	17.964	EPSD	TCGA	11.681	Down-regulation
CAMK_MAPKAPK_MK2_MAPKAPK2_ST	P49815	TSC2	P49137	MAPKAPK2	S1254	L1249M	1249	Missense	distal	-5	no	15.117	14.361	PhosphoSitePlus	TCGA	11.681	Down-regulation
CAMK_MAPKAPK_MK2_MAPKAPK2_ST	P49815	TSC2	P49137	MAPKAPK2	S1259	K1262E	1262	Missense	distal	3	no	12.844	12.972	EPSD	TCGA	11.681	Up-regulation
CAMK_MAPKAPK_MK2_MAPKAPK2_ST	P49815	TSC2	P49137	MAPKAPK2	S1259	P1264L	1264	Missense	distal	5	no	12.844	12.931	EPSD	TCGA;COSMIC	11.681	Up-regulation
CAMK_MAPKAPK_MK2_MAPKAPK2_ST	P49815	TSC2	P49137	MAPKAPK2	S1259	P1265H	1265	Missense	distal	6	no	12.844	12.827	EPSD	TCGA	11.681	Down-regulation
CAMK_MAPKAPK_MK2_MAPKAPK2_ST	P49815	TSC2	P49137	MAPKAPK2	S1269	P1264L	1264	Missense	distal	-5	no	11.620	12.125	EPSD	TCGA;COSMIC	11.681	Gain
CAMK_MAPKAPK_MK2_MAPKAPK2_ST	P49815	TSC2	P49137	MAPKAPK2	S1269	P1265H	1265	Missense	distal	-4	no	11.620	11.791	EPSD	TCGA	11.681	Gain
CAMK_MAPKAPK_MK2_MAPKAPK2_ST	P49815	TSC2	P49137	MAPKAPK2	T1271	R1268C	1268	Missense	distal	-3	no	17.058	8.658	EPSD	TCGA;COSMIC;CCLE	11.681	Loss
CAMK_MAPKAPK_MK2_MAPKAPK2_ST	P49815	TSC2	P49137	MAPKAPK2	T1271	P1264L	1264	Missense	distal	-7	no	17.058	17.092	EPSD	TCGA;COSMIC	11.681	Up-regulation
CAMK_MAPKAPK_MK2_MAPKAPK2_ST	P49815	TSC2	P49137	MAPKAPK2	T1271	P1265H	1265	Missense	distal	-6	no	17.058	17.134	EPSD	TCGA	11.681	Up-regulation
CAMK_MAPKAPK_MK2_MAPKAPK2_ST	P49815	TSC2	P49137	MAPKAPK2	S1336	E1343D	1343	Missense	distal	7	no	12.197	12.008	EPSD	TCGA	11.681	Down-regulation
CAMK_MAPKAPK_MK2_MAPKAPK2_ST	P49815	TSC2	P49137	MAPKAPK2	S1336	S1341N	1341	Missense	distal	5	no	12.197	12.436	EPSD	TCGA;COSMIC	11.681	Up-regulation
CAMK_MAPKAPK_MK2_MAPKAPK2_ST	P49815	TSC2	P49137	MAPKAPK2	S1338	E1343D	1343	Missense	distal	5	no	19.408	19.590	EPSD	TCGA	11.681	Up-regulation
CAMK_MAPKAPK_MK2_MAPKAPK2_ST	P49815	TSC2	P49137	MAPKAPK2	S1338	S1341N	1341	Missense	distal	3	no	19.408	19.252	EPSD	TCGA;COSMIC	11.681	Down-regulation
CAMK_MAPKAPK_MK2_MAPKAPK2_ST	P49815	TSC2	P49137	MAPKAPK2	S1340	E1343D	1343	Missense	distal	3	no	13.750	13.657	EPSD	TCGA	11.681	Down-regulation
CAMK_MAPKAPK_MK2_MAPKAPK2_ST	P49815	TSC2	P49137	MAPKAPK2	S1340	S1341N	1341	Missense	proximal	1	no	13.750	13.268	EPSD	TCGA;COSMIC	11.681	Down-regulation
CAMK_MAPKAPK_MK2_MAPKAPK2_ST	P49815	TSC2	P49137	MAPKAPK2	S1346	H1348Q	1348	Missense	proximal	2	no	12.473	12.680	EPSD	TCGA;COSMIC	11.681	Up-regulation
CAMK_MAPKAPK_MK2_MAPKAPK2_ST	P49815	TSC2	P49137	MAPKAPK2	S1346	E1343D	1343	Missense	distal	-3	no	12.473	10.650	EPSD	TCGA	11.681	Loss
CAMK_MAPKAPK_MK2_MAPKAPK2_ST	P49815	TSC2	P49137	MAPKAPK2	S1346	S1341N	1341	Missense	distal	-5	no	12.473	11.776	EPSD	TCGA;COSMIC	11.681	Down-regulation
CAMK_MAPKAPK_MK2_MAPKAPK2_ST	P49815	TSC2	P49137	MAPKAPK2	S1364	E1360K	1360	Missense	distal	-4	no	14.445	14.612	EPSD	TCGA	11.681	Up-regulation
CAMK_MAPKAPK_MK2_MAPKAPK2_ST	P49815	TSC2	P49137	MAPKAPK2	S1385	S1386I	1386	Missense	proximal	1	no	11.883	11.981	EPSD	TCGA;COSMIC	11.681	Up-regulation
CAMK_MAPKAPK_MK2_MAPKAPK2_ST	P49815	TSC2	P49137	MAPKAPK2	S1387	S1386I	1386	Missense	proximal	-1	no	13.645	13.647	EPSD	TCGA;COSMIC	11.681	Up-regulation
CAMK_MAPKAPK_MK2_MAPKAPK2_ST	P49815	TSC2	P49137	MAPKAPK2	S1388	S1386I	1386	Missense	proximal	-2	no	12.312	7.971	EPSD	TCGA;COSMIC	11.681	Loss
CAMK_MAPKAPK_MK2_MAPKAPK2_ST	P49815	TSC2	P49137	MAPKAPK2	S1447	S1449C	1449	Missense	proximal	2	no	11.840	11.441	EPSD	TCGA;COSMIC	11.681	Loss
CAMK_MAPKAPK_MK2_MAPKAPK2_ST	P49815	TSC2	P49137	MAPKAPK2	S1447	R1451C	1451	Missense	distal	4	no	11.840	11.728	EPSD	TCGA;COSMIC	11.681	Down-regulation
CAMK_MAPKAPK_MK2_MAPKAPK2_ST	P49815	TSC2	P49137	MAPKAPK2	S1449	S1449C	1449	Missense	central	0	yes	15.020	0.000	EPSD	TCGA;COSMIC	11.681	Loss
CAMK_MAPKAPK_MK2_MAPKAPK2_ST	P49815	TSC2	P49137	MAPKAPK2	S1449	R1451C	1451	Missense	proximal	2	no	15.020	14.724	EPSD	TCGA;COSMIC	11.681	Down-regulation
CAMK_MAPKAPK_MK2_MAPKAPK2_ST	P49815	TSC2	P49137	MAPKAPK2	S1454	S1449C	1449	Missense	distal	-5	no	18.407	17.955	EPSD	TCGA;COSMIC	11.681	Down-regulation
CAMK_MAPKAPK_MK2_MAPKAPK2_ST	P49815	TSC2	P49137	MAPKAPK2	S1454	R1457Q	1457	Missense	distal	3	no	18.407	18.311	EPSD	TCGA;COSMIC	11.681	Down-regulation
CAMK_MAPKAPK_MK2_MAPKAPK2_ST	P49815	TSC2	P49137	MAPKAPK2	S1454	R1451C	1451	Missense	distal	-3	no	18.407	10.007	EPSD	TCGA;COSMIC	11.681	Loss
CAMK_MAPKAPK_MK2_MAPKAPK2_ST	P49815	TSC2	P49137	MAPKAPK2	T1462	S1466L	1466	Missense	distal	4	no	14.028	13.876	EPSD	TCGA	11.681	Down-regulation
CAMK_MAPKAPK_MK2_MAPKAPK2_ST	P49815	TSC2	P49137	MAPKAPK2	T1462	R1457Q	1457	Missense	distal	-5	no	14.028	13.310	EPSD	TCGA;COSMIC	11.681	Down-regulation
CAMK_MAPKAPK_MK2_MAPKAPK2_ST	P49815	TSC2	P49137	MAPKAPK2	S1464	S1466L	1466	Missense	proximal	2	no	13.136	12.721	EPSD	TCGA	11.681	Down-regulation
CAMK_MAPKAPK_MK2_MAPKAPK2_ST	P49815	TSC2	P49137	MAPKAPK2	S1464	R1457Q	1457	Missense	distal	-7	no	13.136	13.223	EPSD	TCGA;COSMIC	11.681	Up-regulation
CAMK_MAPKAPK_MK2_MAPKAPK2_ST	P49815	TSC2	P49137	MAPKAPK2	S1466	S1466L	1466	Missense	central	0	yes	13.799	0.000	EPSD	TCGA	11.681	Loss
CAMK_MAPKAPK_MK2_MAPKAPK2_ST	P49815	TSC2	P49137	MAPKAPK2	S1730	S1730P	1730	Missense	central	0	yes	14.551	0.000	EPSD	TCGA;COSMIC	11.681	Loss
CAMK_MAPKAPK_MK2_MAPKAPK2_ST	P49815	TSC2	P49137	MAPKAPK2	S1730	D1734N	1734	Missense	distal	4	no	14.551	14.552	EPSD	TCGA	11.681	Up-regulation
CAMK_MAPKAPK_MK2_MAPKAPK2_ST	P49815	TSC2	P49137	MAPKAPK2	S1798	E1805K	1805	Missense	distal	7	no	15.750	15.477	EPSD	TCGA;COSMIC	11.681	Down-regulation
CAMK_MAPKAPK_MK2_MAPKAPK2_ST	P49815	TSC2	P49137	MAPKAPK2	S1798	S1798C	1798	Missense	central	0	yes	15.750	0.000	EPSD	TCGA;COSMIC	11.681	Loss
CAMK_MAPKAPK_MK2_MAPKAPK2_ST	P49815	TSC2	P49137	MAPKAPK2	S1798	S1798F	1798	Missense	central	0	yes	15.750	0.000	EPSD	TCGA;COSMIC	11.681	Loss
CAMK_MAPKAPK_MK2_MAPKAPK2_ST	P30307	CDC25C	P49137	MAPKAPK2	S38	D36Y	36	Missense	proximal	-2	no	14.586	14.074	EPSD	TCGA;ICGC	11.681	Down-regulation
CAMK_MAPKAPK_MK2_MAPKAPK2_ST	P30307	CDC25C	P49137	MAPKAPK2	S75	D73N	73	Missense	proximal	-2	no	11.119	13.115	EPSD	TCGA;ICGC;COSMIC	11.681	Gain
CAMK_MAPKAPK_MK2_MAPKAPK2_ST	P30307	CDC25C	P49137	MAPKAPK2	S216	N222K	222	Missense	distal	6	no	19.967	19.960	PhosphoSitePlus	TCGA;ICGC;COSMIC	11.681	Down-regulation
CAMK_MAPKAPK_MK2_MAPKAPK2_ST	P30307	CDC25C	P49137	MAPKAPK2	S216	P215Q	215	Missense	proximal	-1	no	19.967	19.980	PhosphoSitePlus	TCGA;ICGC;COSMIC	11.681	Up-regulation
CAMK_MAPKAPK_MK2_MAPKAPK2_ST	P30307	CDC25C	P49137	MAPKAPK2	S216	R213H	213	Missense	distal	-3	no	19.967	15.208	PhosphoSitePlus	TCGA;ICGC;COSMIC	11.681	Down-regulation
CAMK_MAPKAPK_MK2_MAPKAPK2_ST	P30307	CDC25C	P49137	MAPKAPK2	S216	R213C	213	Missense	distal	-3	no	19.967	11.567	PhosphoSitePlus	TCGA;ICGC;COSMIC	11.681	Loss
CAMK_MAPKAPK_MK2_MAPKAPK2_ST	P30307	CDC25C	P49137	MAPKAPK2	S216	S214F	214	Missense	proximal	-2	no	19.967	14.541	PhosphoSitePlus	TCGA;ICGC;COSMIC	11.681	Down-regulation
CAMK_MAPKAPK_MK2_MAPKAPK2_ST	P30307	CDC25C	P49137	MAPKAPK2	S216	L221S	221	Missense	distal	5	no	19.967	19.798	PhosphoSitePlus	TCGA;ICGC;COSMIC	11.681	Down-regulation
CAMK_MAPKAPK_MK2_MAPKAPK2_ST	P30307	CDC25C	P49137	MAPKAPK2	S216	P218S	218	Missense	proximal	2	no	19.967	20.159	PhosphoSitePlus	TCGA;ICGC	11.681	Up-regulation
CAMK_MAPKAPK_MK2_MAPKAPK2_ST	Q14457	BECN1	P49137	MAPKAPK2	S90	P84L	84	Missense	distal	-6	no	16.933	16.965	PhosphoSitePlus	TCGA;ICGC;COSMIC	11.681	Up-regulation
CAMK_MAPKAPK_MK2_MAPKAPK2_ST	Q14457	BECN1	P49137	MAPKAPK2	S96	T98P	98	Missense	proximal	2	no	13.051	12.836	EPSD	TCGA;ICGC;COSMIC	11.681	Down-regulation
CAMK_MAPKAPK_MK2_MAPKAPK2_ST	Q14457	BECN1	P49137	MAPKAPK2	S295	R292H	292	Missense	distal	-3	no	15.735	10.975	EPSD	TCGA;ICGC	11.681	Loss
CAMK_MAPKAPK_MK2_MAPKAPK2_ST	Q14457	BECN1	P49137	MAPKAPK2	S414	G411S	411	Missense	distal	-3	no	8.972	13.302	EPSD	TCGA;ICGC;COSMIC	11.681	Gain
CAMK_MAPKAPK_MK2_MAPKAPK2_ST	P35900	KRT20	P49137	MAPKAPK2	S13	V20L	20	Missense	distal	7	no	19.361	19.228	PhosphoSitePlus	TCGA;ICGC;COSMIC	11.681	Down-regulation
CAMK_MAPKAPK_MK2_MAPKAPK2_ST	P35900	KRT20	P49137	MAPKAPK2	S15	V20L	20	Missense	distal	5	no	13.805	13.791	EPSD	TCGA;ICGC;COSMIC	11.681	Down-regulation
CAMK_MAPKAPK_MK2_MAPKAPK2_ST	P35900	KRT20	P49137	MAPKAPK2	T31	T31M	31	Missense	central	0	yes	13.404	0.000	EPSD	TCGA;ICGC;COSMIC;CCLE	11.681	Loss
CAMK_MAPKAPK_MK2_MAPKAPK2_ST	P35900	KRT20	P49137	MAPKAPK2	T31	R28C	28	Missense	distal	-3	no	13.404	5.004	EPSD	TCGA;ICGC;COSMIC	11.681	Loss
CAMK_MAPKAPK_MK2_MAPKAPK2_ST	P35900	KRT20	P49137	MAPKAPK2	T31	G37E	37	Missense	distal	6	no	13.404	13.418	EPSD	TCGA;ICGC;COSMIC	11.681	Up-regulation
CAMK_MAPKAPK_MK2_MAPKAPK2_ST	P35900	KRT20	P49137	MAPKAPK2	T31	P33T	33	Missense	proximal	2	no	13.404	13.619	EPSD	TCGA;ICGC;COSMIC	11.681	Up-regulation
CAMK_MAPKAPK_MK2_MAPKAPK2_ST	P35900	KRT20	P49137	MAPKAPK2	T31	T31A	31	Missense	central	0	yes	13.404	0.000	EPSD	TCGA;ICGC;COSMIC	11.681	Loss
CAMK_MAPKAPK_MK2_MAPKAPK2_ST	P35900	KRT20	P49137	MAPKAPK2	S34	T31M	31	Missense	distal	-3	no	12.843	10.327	EPSD	TCGA;ICGC;COSMIC;CCLE	11.681	Loss
CAMK_MAPKAPK_MK2_MAPKAPK2_ST	P35900	KRT20	P49137	MAPKAPK2	S34	G40R	40	Missense	distal	6	no	12.843	12.871	EPSD	TCGA;ICGC;COSMIC	11.681	Up-regulation
CAMK_MAPKAPK_MK2_MAPKAPK2_ST	P35900	KRT20	P49137	MAPKAPK2	S34	R28C	28	Missense	distal	-6	no	12.843	12.893	EPSD	TCGA;ICGC;COSMIC	11.681	Up-regulation
CAMK_MAPKAPK_MK2_MAPKAPK2_ST	P35900	KRT20	P49137	MAPKAPK2	S34	G41S	41	Missense	distal	7	no	12.843	13.048	EPSD	TCGA;ICGC;COSMIC	11.681	Up-regulation
CAMK_MAPKAPK_MK2_MAPKAPK2_ST	P35900	KRT20	P49137	MAPKAPK2	S34	G37E	37	Missense	distal	3	no	12.843	12.926	EPSD	TCGA;ICGC;COSMIC	11.681	Up-regulation
CAMK_MAPKAPK_MK2_MAPKAPK2_ST	P35900	KRT20	P49137	MAPKAPK2	S34	P33T	33	Missense	proximal	-1	no	12.843	12.838	EPSD	TCGA;ICGC;COSMIC	11.681	Down-regulation
CAMK_MAPKAPK_MK2_MAPKAPK2_ST	P35900	KRT20	P49137	MAPKAPK2	S34	T31A	31	Missense	distal	-3	no	12.843	9.497	EPSD	TCGA;ICGC;COSMIC	11.681	Loss
CAMK_MAPKAPK_MK2_MAPKAPK2_ST	P35900	KRT20	P49137	MAPKAPK2	S83	L85Q	85	Missense	proximal	2	no	13.206	13.213	EPSD	TCGA;ICGC;COSMIC	11.681	Up-regulation
CAMK_MAPKAPK_MK2_MAPKAPK2_ST	P35900	KRT20	P49137	MAPKAPK2	S96	V100M	100	Missense	distal	4	no	13.788	13.820	EPSD	TCGA;ICGC;COSMIC	11.681	Up-regulation
CAMK_MAPKAPK_MK2_MAPKAPK2_ST	P35900	KRT20	P49137	MAPKAPK2	S118	I124T	124	Missense	distal	6	no	12.619	12.642	EPSD	TCGA;ICGC;COSMIC	11.681	Up-regulation
CAMK_MAPKAPK_MK2_MAPKAPK2_ST	P35900	KRT20	P49137	MAPKAPK2	S118	E125K	125	Missense	distal	7	no	12.619	12.346	EPSD	TCGA;ICGC;COSMIC	11.681	Down-regulation
CAMK_MAPKAPK_MK2_MAPKAPK2_ST	P35900	KRT20	P49137	MAPKAPK2	S118	R115H	115	Missense	distal	-3	no	12.619	7.859	EPSD	TCGA;ICGC	11.681	Loss
CAMK_MAPKAPK_MK2_MAPKAPK2_ST	P35900	KRT20	P49137	MAPKAPK2	S293	T292N	292	Missense	proximal	-1	no	17.428	17.447	EPSD	TCGA;ICGC;COSMIC	11.681	Up-regulation
CAMK_MAPKAPK_MK2_MAPKAPK2_ST	P35900	KRT20	P49137	MAPKAPK2	S293	R291C	291	Missense	proximal	-2	no	17.428	16.217	EPSD	TCGA;ICGC;COSMIC	11.681	Down-regulation
CAMK_MAPKAPK_MK2_MAPKAPK2_ST	P35900	KRT20	P49137	MAPKAPK2	S293	E288K	288	Missense	distal	-5	no	17.428	16.821	EPSD	TCGA;ICGC	11.681	Down-regulation
CAMK_MAPKAPK_MK2_MAPKAPK2_ST	P35900	KRT20	P49137	MAPKAPK2	S295	T292N	292	Missense	distal	-3	no	12.513	11.843	EPSD	TCGA;ICGC;COSMIC	11.681	Down-regulation
CAMK_MAPKAPK_MK2_MAPKAPK2_ST	P35900	KRT20	P49137	MAPKAPK2	S295	R291C	291	Missense	distal	-4	no	12.513	12.741	EPSD	TCGA;ICGC;COSMIC	11.681	Up-regulation
CAMK_MAPKAPK_MK2_MAPKAPK2_ST	P35900	KRT20	P49137	MAPKAPK2	S295	E288K	288	Missense	distal	-7	no	12.513	12.553	EPSD	TCGA;ICGC	11.681	Up-regulation
CAMK_CAMKL_MARK_MARK3_ST	P27448	MARK3	P27448-3	MARK3	S383	S380C	380	Missense	distal	-3	no	295.051	297.072	EPSD	TCGA;ICGC;COSMIC	255.132	Up-regulation
CAMK_CAMKL_MARK_MARK3_ST	P27448	MARK3	P27448-3	MARK3	S383	K386R	386	Missense	distal	3	no	295.051	295.487	EPSD	TCGA;COSMIC	255.132	Up-regulation
CAMK_CAMKL_MARK_MARK3_ST	P27448	MARK3	P27448-3	MARK3	S390	K386R	386	Missense	distal	-4	no	263.021	251.181	EPSD	TCGA;COSMIC	255.132	Loss
CAMK_CAMKL_MARK_MARK3_ST	P27448	MARK3	P27448-3	MARK3	S391	G398D	398	Missense	distal	7	no	258.245	258.402	EPSD	TCGA;ICGC;COSMIC	255.132	Up-regulation
CAMK_CAMKL_MARK_MARK3_ST	P27448	MARK3	P27448-3	MARK3	S391	K386R	386	Missense	distal	-5	no	258.245	163.349	EPSD	TCGA;COSMIC	255.132	Loss
CAMK_CAMKL_MARK_MARK3_ST	P27448	MARK3	P27448-3	MARK3	S436	A431V	431	Missense	distal	-5	no	265.635	257.691	EPSD	TCGA;ICGC;COSMIC;GDSC;CCLE	255.132	Down-regulation
CAMK_CAMKL_MARK_MARK3_ST	P27448	MARK3	P27448-3	MARK3	S451	S456G	456	Missense	distal	5	no	317.408	294.887	EPSD	TCGA;ICGC;COSMIC	255.132	Down-regulation
CAMK_CAMKL_MARK_MARK3_ST	P27448	MARK3	P27448-3	MARK3	S451	S458I	458	Missense	distal	7	no	317.408	317.335	EPSD	TCGA;ICGC;COSMIC	255.132	Down-regulation
CAMK_CAMKL_MARK_MARK3_ST	P27448	MARK3	P27448-3	MARK3	S452	S456G	456	Missense	distal	4	no	394.378	395.055	EPSD	TCGA;ICGC;COSMIC	255.132	Up-regulation
CAMK_CAMKL_MARK_MARK3_ST	P27448	MARK3	P27448-3	MARK3	S452	S458I	458	Missense	distal	6	no	394.378	399.496	EPSD	TCGA;ICGC;COSMIC	255.132	Up-regulation
CAMK_CAMKL_MARK_MARK3_ST	P27448	MARK3	P27448-3	MARK3	S455	S456G	456	Missense	proximal	1	no	258.075	258.069	EPSD	TCGA;ICGC;COSMIC	255.132	Down-regulation
CAMK_CAMKL_MARK_MARK3_ST	P27448	MARK3	P27448-3	MARK3	S455	S458I	458	Missense	distal	3	no	258.075	258.486	EPSD	TCGA;ICGC;COSMIC	255.132	Up-regulation
CAMK_CAMKL_MARK_MARK3_ST	P27448	MARK3	P27448-3	MARK3	S458	S456G	456	Missense	proximal	-2	no	318.747	313.205	EPSD	TCGA;ICGC;COSMIC	255.132	Down-regulation
CAMK_CAMKL_MARK_MARK3_ST	P27448	MARK3	P27448-3	MARK3	S458	S458I	458	Missense	central	0	yes	318.747	0.000	EPSD	TCGA;ICGC;COSMIC	255.132	Loss
CAMK_CAMKL_MARK_MARK3_ST	P27448	MARK3	P27448-3	MARK3	S469	A466D	466	Missense	distal	-3	no	343.219	347.001	EPSD	TCGA;ICGC;COSMIC	255.132	Up-regulation
CAMK_CAMKL_MARK_MARK3_ST	P27448	MARK3	P27448-3	MARK3	S476	A481V	481	Missense	distal	5	no	355.903	337.593	EPSD	TCGA;ICGC;COSMIC	255.132	Down-regulation
CAMK_CAMKL_MARK_MARK3_ST	P27448	MARK3	P27448-3	MARK3	S499	R505P	505	Missense	distal	6	no	263.040	263.125	EPSD	TCGA;ICGC;COSMIC	255.132	Up-regulation
CAMK_CAMKL_MARK_MARK3_ST	P27448	MARK3	P27448-3	MARK3	S499	R505Q	505	Missense	distal	6	no	263.040	246.616	EPSD	TCGA;ICGC;COSMIC	255.132	Loss
CAMK_CAMKL_MARK_MARK3_ST	P27448	MARK3	P27448-3	MARK3	S540	I544V	544	Missense	distal	4	no	256.896	257.176	EPSD	TCGA;ICGC;COSMIC	255.132	Up-regulation
CAMK_CAMKL_MARK_MARK3_ST	P27448	MARK3	P27448-3	MARK3	S540	S546I	546	Missense	distal	6	no	256.896	262.014	EPSD	TCGA;ICGC;COSMIC	255.132	Up-regulation
CAMK_CAMKL_MARK_MARK3_ST	P27448	MARK3	P27448-3	MARK3	T564	P569L	569	Missense	distal	5	no	326.655	368.366	EPSD	TCGA;ICGC;COSMIC	255.132	Up-regulation
CAMK_CAMKL_MARK_MARK3_ST	P27448	MARK3	P27448-3	MARK3	T564	R570Q	570	Missense	distal	6	no	326.655	310.232	EPSD	TCGA;ICGC;COSMIC	255.132	Down-regulation
CAMK_CAMKL_MARK_MARK3_ST	P27448	MARK3	P27448-3	MARK3	T564	T559N	559	Missense	distal	-5	no	326.655	357.562	EPSD	TCGA;ICGC	255.132	Up-regulation
CAMK_CAMKL_MARK_MARK3_ST	P27448	MARK3	P27448-3	MARK3	T576	A575T	575	Missense	proximal	-1	no	260.044	260.049	EPSD	TCGA;ICGC;COSMIC	255.132	Up-regulation
CAMK_CAMKL_MARK_MARK3_ST	P27448	MARK3	P27448-3	MARK3	T576	P569L	569	Missense	distal	-7	no	260.044	255.340	EPSD	TCGA;ICGC;COSMIC	255.132	Down-regulation
CAMK_CAMKL_MARK_MARK3_ST	P27448	MARK3	P27448-3	MARK3	T576	R570Q	570	Missense	distal	-6	no	260.044	261.260	EPSD	TCGA;ICGC;COSMIC	255.132	Up-regulation
CAMK_CAMKL_MARK_MARK3_ST	P27448	MARK3	P27448-3	MARK3	T576	P580H	580	Missense	distal	4	no	260.044	260.327	EPSD	TCGA;ICGC	255.132	Up-regulation
CAMK_CAMKL_MARK_MARK3_ST	P27448	MARK3	P27448-3	MARK3	T602	T609N	609	Missense	distal	7	no	369.966	369.477	EPSD;PhosphoSitePlus	TCGA;ICGC	255.132	Down-regulation
CAMK_CAMKL_MARK_MARK3_ST	P27448	MARK3	P27448-3	MARK3	S606	T609N	609	Missense	distal	3	no	332.106	331.441	EPSD;PhosphoSitePlus	TCGA;ICGC	255.132	Down-regulation
CAMK_CAMKL_MARK_MARK3_ST	P27448	MARK3	P27448-3	MARK3	S606	T613I	613	Missense	distal	7	no	332.106	333.265	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	255.132	Up-regulation
CAMK_CAMKL_MARK_MARK3_ST	P27448	MARK3	P27448-3	MARK3	S663	M670L	670	Missense	distal	7	no	360.773	360.401	EPSD	TCGA;COSMIC	255.132	Down-regulation
CAMK_CAMKL_MARK_MARK3_ST	P27448	MARK3	P27448-3	MARK3	S668	P672T	672	Missense	distal	4	no	261.915	261.403	EPSD	TCGA;COSMIC	255.132	Down-regulation
CAMK_CAMKL_MARK_MARK3_ST	P27448	MARK3	P27448-3	MARK3	S668	M670L	670	Missense	proximal	2	no	261.915	259.771	EPSD	TCGA;COSMIC	255.132	Down-regulation
CAMK_CAMKL_MARK_MARK3_ST	P27448	MARK3	P27448-3	MARK3	S668	P672S	672	Missense	distal	4	no	261.915	261.325	EPSD	TCGA;COSMIC	255.132	Down-regulation
CAMK_CAMKL_MARK_MARK3_ST	P27448	MARK3	P27448-3	MARK3	S669	P672T	672	Missense	distal	3	no	418.837	418.829	EPSD	TCGA;COSMIC	255.132	Down-regulation
CAMK_CAMKL_MARK_MARK3_ST	P27448	MARK3	P27448-3	MARK3	S669	M670L	670	Missense	proximal	1	no	418.837	418.831	EPSD	TCGA;COSMIC	255.132	Down-regulation
CAMK_CAMKL_MARK_MARK3_ST	P27448	MARK3	P27448-3	MARK3	S669	P672S	672	Missense	distal	3	no	418.837	418.483	EPSD	TCGA;COSMIC	255.132	Down-regulation
CAMK_CAMKL_MARK_MARK3_ST	P27448	MARK3	P27448-3	MARK3	S724	C718Y	718	Missense	distal	-6	no	353.601	354.641	EPSD	TCGA;COSMIC	255.132	Up-regulation
CAMK_CAMKL_MARK_MARK3_ST	P27448	MARK3	P27448-3	MARK3	S724	S724A	724	Missense	central	0	yes	353.601	0.000	EPSD	TCGA	255.132	Loss
CK1_CK1_CK1-G_CSNK1G2_ST	Q14457	BECN1	P78368	CSNK1G2	S7	S4T	4	Missense	distal	-3	no	1.776	1.775	EPSD	TCGA;ICGC;COSMIC	1.578	Down-regulation
CK1_CK1_CK1-G_CSNK1G2_ST	Q14457	BECN1	P78368	CSNK1G2	T11	S4T	4	Missense	distal	-7	no	2.345	2.307	EPSD	TCGA;ICGC;COSMIC	1.578	Down-regulation
CK1_CK1_CK1-G_CSNK1G2_ST	Q14457	BECN1	P78368	CSNK1G2	T11	F16L	16	Missense	distal	5	no	2.345	2.375	EPSD	TCGA;ICGC;COSMIC	1.578	Up-regulation
CK1_CK1_CK1-G_CSNK1G2_ST	Q14457	BECN1	P78368	CSNK1G2	S96	T98P	98	Missense	proximal	2	no	3.351	3.346	EPSD	TCGA;ICGC;COSMIC	1.578	Down-regulation
CK1_CK1_CK1-G_CSNK1G2_ST	Q14457	BECN1	P78368	CSNK1G2	T406	I403T	403	Missense	distal	-3	no	7.721	7.700	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	1.578	Down-regulation
CK1_CK1_CK1-G_CSNK1G2_ST	Q14457	BECN1	P78368	CSNK1G2	T406	G411S	411	Missense	distal	5	no	7.721	7.664	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	1.578	Down-regulation
CK1_CK1_CK1-G_CSNK1G2_ST	Q14457	BECN1	P78368	CSNK1G2	T406	I403N	403	Missense	distal	-3	no	7.721	7.698	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	1.578	Down-regulation
CK1_CK1_CK1-G_CSNK1G2_ST	Q14457	BECN1	P78368	CSNK1G2	S409	I403T	403	Missense	distal	-6	no	8.514	8.404	PhosphoSitePlus;EPSD	TCGA;ICGC;COSMIC	1.578	Down-regulation
CK1_CK1_CK1-G_CSNK1G2_ST	Q14457	BECN1	P78368	CSNK1G2	S409	G411S	411	Missense	proximal	2	no	8.514	8.368	PhosphoSitePlus;EPSD	TCGA;ICGC;COSMIC	1.578	Down-regulation
CK1_CK1_CK1-G_CSNK1G2_ST	Q14457	BECN1	P78368	CSNK1G2	S409	I403N	403	Missense	distal	-6	no	8.514	8.454	PhosphoSitePlus;EPSD	TCGA;ICGC;COSMIC	1.578	Down-regulation
CK1_CK1_CK1-G_CSNK1G2_ST	P84022	SMAD3	P78368	CSNK1G2	T8	P9S	9	Missense	proximal	1	no	3.665	3.618	EPSD	TCGA;ICGC;COSMIC	1.578	Down-regulation
CK1_CK1_CK1-G_CSNK1G2_ST	P84022	SMAD3	P78368	CSNK1G2	T388	A382V	382	Missense	distal	-6	no	3.568	3.587	EPSD	TCGA;ICGC;COSMIC	1.578	Up-regulation
CK1_CK1_CK1-G_CSNK1G2_ST	P84022	SMAD3	P78368	CSNK1G2	T388	C394F	394	Missense	distal	6	no	3.568	3.571	EPSD	TCGA;ICGC;COSMIC	1.578	Up-regulation
CK1_CK1_CK1-G_CSNK1G2_ST	P84022	SMAD3	P78368	CSNK1G2	T388	P393L	393	Missense	distal	5	no	3.568	3.634	EPSD	TCGA;ICGC;COSMIC	1.578	Up-regulation
CK1_CK1_CK1-G_CSNK1G2_ST	O14654	IRS4	P78368	CSNK1G2	S66	S62F	62	Missense	distal	-4	no	3.144	3.150	EPSD	TCGA;ICGC;COSMIC	1.578	Up-regulation
CK1_CK1_CK1-G_CSNK1G2_ST	O14654	IRS4	P78368	CSNK1G2	S68	S62F	62	Missense	distal	-6	no	1.608	1.748	EPSD	TCGA;ICGC;COSMIC	1.578	Up-regulation
CK1_CK1_CK1-G_CSNK1G2_ST	O14654	IRS4	P78368	CSNK1G2	S68	V75A	75	Missense	distal	7	no	1.608	1.599	EPSD	TCGA;ICGC	1.578	Down-regulation
CK1_CK1_CK1-G_CSNK1G2_ST	O14654	IRS4	P78368	CSNK1G2	S558	G565V	565	Missense	distal	7	no	1.678	1.659	EPSD	TCGA;ICGC;COSMIC	1.578	Down-regulation
CK1_CK1_CK1-G_CSNK1G2_ST	O14654	IRS4	P78368	CSNK1G2	S558	A553V	553	Missense	distal	-5	no	1.678	1.648	EPSD	TCGA;ICGC;COSMIC	1.578	Down-regulation
CK1_CK1_CK1-G_CSNK1G2_ST	O14654	IRS4	P78368	CSNK1G2	S558	G559S	559	Missense	proximal	1	no	1.678	1.528	EPSD	TCGA;ICGC;COSMIC	1.578	Loss
CK1_CK1_CK1-G_CSNK1G2_ST	O14654	IRS4	P78368	CSNK1G2	S570	G565V	565	Missense	distal	-5	no	1.794	1.689	EPSD	TCGA;ICGC;COSMIC	1.578	Down-regulation
CK1_CK1_CK1-G_CSNK1G2_ST	O14654	IRS4	P78368	CSNK1G2	S570	G567R	567	Missense	distal	-3	no	1.794	1.800	EPSD	TCGA;ICGC;COSMIC	1.578	Up-regulation
CK1_CK1_CK1-G_CSNK1G2_ST	O14654	IRS4	P78368	CSNK1G2	S570	G571V	571	Missense	proximal	1	no	1.794	1.674	EPSD	TCGA;ICGC;COSMIC;GDSC;CCLE	1.578	Down-regulation
CK1_CK1_CK1-G_CSNK1G2_ST	O14654	IRS4	P78368	CSNK1G2	T643	G650V	650	Missense	distal	7	no	3.133	3.114	EPSD	TCGA;ICGC	1.578	Down-regulation
CK1_CK1_CK1-G_CSNK1G2_ST	O14654	IRS4	P78368	CSNK1G2	T643	G650W	650	Missense	distal	7	no	3.133	3.097	EPSD	TCGA;ICGC;COSMIC	1.578	Down-regulation
CK1_CK1_CK1-G_CSNK1G2_ST	O14654	IRS4	P78368	CSNK1G2	S770	K766T	766	Missense	distal	-4	no	2.537	2.390	EPSD	TCGA;ICGC	1.578	Down-regulation
CK1_CK1_CK1-G_CSNK1G2_ST	O14654	IRS4	P78368	CSNK1G2	S770	N765S	765	Missense	distal	-5	no	2.537	2.614	EPSD	TCGA;ICGC;COSMIC	1.578	Up-regulation
CK1_CK1_CK1-G_CSNK1G2_ST	O14654	IRS4	P78368	CSNK1G2	S804	S802T	802	Missense	proximal	-2	no	1.640	1.634	EPSD	TCGA;ICGC;COSMIC	1.578	Down-regulation
CK1_CK1_CK1-G_CSNK1G2_ST	O14654	IRS4	P78368	CSNK1G2	S804	S810Y	810	Missense	distal	6	no	1.640	1.536	EPSD	TCGA;ICGC	1.578	Loss
CK1_CK1_CK1-G_CSNK1G2_ST	O14654	IRS4	P78368	CSNK1G2	S804	F809L	809	Missense	distal	5	no	1.640	1.670	EPSD	TCGA;ICGC;COSMIC	1.578	Up-regulation
CK1_CK1_CK1-G_CSNK1G2_ST	O14654	IRS4	P78368	CSNK1G2	S804	K803R	803	Missense	proximal	-1	no	1.640	1.810	EPSD	TCGA;ICGC;COSMIC	1.578	Up-regulation
AGC_PKC_PKCd_PRKCQ_ST	O94992	HEXIM1	Q04759	PRKCQ	S268	S268L	268	Missense	central	0	yes	1.985	0.000	EPSD	TCGA;ICGC;COSMIC	1.204	Loss
AGC_PKC_PKCd_PRKCQ_ST	O94992	HEXIM1	Q04759	PRKCQ	S268	E272D	272	Missense	distal	4	no	1.985	1.978	EPSD	TCGA;ICGC;COSMIC	1.204	Down-regulation
AGC_PKC_PKCd_PRKCQ_ST	P35241	RDX	Q04759	PRKCQ	S249	I245F	245	Missense	distal	-4	no	1.618	1.627	EPSD	TCGA;COSMIC	1.204	Up-regulation
AGC_PKC_PKCd_PRKCQ_ST	P35241	RDX	Q04759	PRKCQ	S249	R246K	246	Missense	distal	-3	no	1.618	1.200	EPSD	TCGA;COSMIC	1.204	Loss
AGC_PKC_PKCd_PRKCQ_ST	P35241	RDX	Q04759	PRKCQ	S249	K254T	254	Missense	distal	5	no	1.618	1.599	EPSD	TCGA;ICGC;COSMIC	1.204	Down-regulation
AGC_PKC_PKCd_PRKCQ_ST	P35241	RDX	Q04759	PRKCQ	S249	F255Y	255	Missense	distal	6	no	1.618	1.616	EPSD	TCGA;COSMIC	1.204	Down-regulation
AGC_PKC_PKCd_PRKCQ_ST	P35241	RDX	Q04759	PRKCQ	T564	R569Q	569	Missense	distal	5	no	1.468	1.443	PhosphoSitePlus	TCGA;ICGC	1.204	Down-regulation
AGC_PKC_PKCd_PRKCQ_ST	P35241	RDX	Q04759	PRKCQ	T564	D560Y	560	Missense	distal	-4	no	1.468	1.473	PhosphoSitePlus	TCGA;COSMIC	1.204	Up-regulation
AGC_PKC_PKCd_PRKCQ_ST	P35241	RDX	Q04759	PRKCQ	T564	R566Q	566	Missense	proximal	2	no	1.468	1.230	PhosphoSitePlus	TCGA;COSMIC	1.204	Down-regulation
AGC_PKC_PKCd_PRKCQ_ST	P35241	RDX	Q04759	PRKCQ	T564	A557T	557	Missense	distal	-7	no	1.468	1.469	PhosphoSitePlus	TCGA;ICGC;COSMIC	1.204	Up-regulation
AGC_PKC_PKCd_PRKCQ_ST	O15530	PDPK1	Q04759	PRKCQ	S410	G409S	409	Missense	proximal	-1	no	1.791	1.795	EPSD	TCGA;COSMIC	1.204	Up-regulation
AGC_PKC_PKCd_PRKCQ_ST	Q92934	BAD	Q04759	PRKCQ	S74	S71I	71	Missense	distal	-3	no	1.454	1.233	EPSD	TCGA;ICGC;COSMIC	1.204	Down-regulation
AGC_PKC_PKCd_PRKCQ_ST	Q92934	BAD	Q04759	PRKCQ	S75	S71I	71	Missense	distal	-4	no	2.338	2.313	PhosphoSitePlus;EPSD	TCGA;ICGC;COSMIC	1.204	Down-regulation
AGC_PKC_PKCd_PRKCQ_ST	Q92934	BAD	Q04759	PRKCQ	S97	A100T	100	Missense	distal	3	no	1.818	1.811	EPSD	TCGA;ICGC;COSMIC	1.204	Down-regulation
AGC_PKC_PKCd_PRKCQ_ST	Q92934	BAD	Q04759	PRKCQ	S99	A100T	100	Missense	proximal	1	no	2.414	2.410	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	1.204	Down-regulation
AGC_PKC_PKCd_PRKCQ_ST	Q92934	BAD	Q04759	PRKCQ	S118	M117I	117	Missense	proximal	-1	no	2.130	2.127	EPSD	TCGA;ICGC;COSMIC	1.204	Down-regulation
AGC_PKC_PKCd_PRKCQ_ST	Q92934	BAD	Q04759	PRKCQ	S134	R131H	131	Missense	distal	-3	no	1.741	0.628	EPSD	TCGA;ICGC;COSMIC	1.204	Loss
AGC_PKC_PKCd_PRKCQ_ST	Q92934	BAD	Q04759	PRKCQ	S134	G136D	136	Missense	proximal	2	no	1.741	1.730	EPSD	TCGA;ICGC;COSMIC	1.204	Down-regulation
AGC_PKC_PKCd_PRKCQ_ST	Q92934	BAD	Q04759	PRKCQ	S134	S134I	134	Missense	central	0	yes	1.741	0.000	EPSD	TCGA	1.204	Loss
AGC_PKC_PKCd_PRKCQ_ST	Q92934	BAD	Q04759	PRKCQ	S164	G162V	162	Missense	proximal	-2	no	1.894	1.825	EPSD	TCGA;ICGC;COSMIC	1.204	Down-regulation
AGC_PKC_PKCd_PRKCQ_ST	Q92934	BAD	Q04759	PRKCQ	S164	S164F	164	Missense	central	0	yes	1.894	0.000	EPSD	TCGA;ICGC;COSMIC;GDSC;CCLE	1.204	Loss
AGC_PKC_PKCd_PRKCQ_ST	Q92934	BAD	Q04759	PRKCQ	S164	S167P	167	Missense	distal	3	no	1.894	1.890	EPSD	TCGA;COSMIC	1.204	Down-regulation
AGC_PKC_PKCd_PRKCQ_ST	Q92934	BAD	Q04759	PRKCQ	S164	S163N	163	Missense	proximal	-1	no	1.894	1.891	EPSD	TCGA;ICGC;COSMIC	1.204	Down-regulation
AGC_PKC_PKCd_PRKCQ_ST	Q92934	BAD	Q04759	PRKCQ	S164	G162E	162	Missense	proximal	-2	no	1.894	1.832	EPSD	TCGA;ICGC	1.204	Down-regulation
AGC_PKC_PKCd_PRKCQ_ST	P15311	EZR	Q04759	PRKCQ	S66	K60M	60	Missense	distal	-6	no	1.743	1.836	EPSD	TCGA;ICGC;COSMIC	1.204	Up-regulation
AGC_PKC_PKCd_PRKCQ_ST	P15311	EZR	Q04759	PRKCQ	S112	G109R	109	Missense	distal	-3	no	0.672	1.990	EPSD	TCGA;ICGC;COSMIC	1.204	Gain
AGC_PKC_PKCd_PRKCQ_ST	P15311	EZR	Q04759	PRKCQ	S249	S249F	249	Missense	central	0	yes	1.607	0.000	EPSD	TCGA;ICGC;COSMIC	1.204	Loss
AGC_PKC_PKCd_PRKCQ_ST	P15311	EZR	Q04759	PRKCQ	T332	R330T	330	Missense	proximal	-2	no	1.880	1.194	EPSD	TCGA;ICGC;COSMIC	1.204	Loss
AGC_PKC_PKCd_PRKCQ_ST	P15311	EZR	Q04759	PRKCQ	S366	E362K	362	Missense	distal	-4	no	1.178	1.212	EPSD	TCGA;ICGC;COSMIC	1.204	Gain
AGC_PKC_PKCd_PRKCQ_ST	P15311	EZR	Q04759	PRKCQ	S366	E364D	364	Missense	proximal	-2	no	1.178	1.207	EPSD	TCGA;ICGC	1.204	Gain
AGC_PKC_PKCd_PRKCQ_ST	P15311	EZR	Q04759	PRKCQ	T567	R562Q	562	Missense	distal	-5	no	1.525	1.289	PhosphoSitePlus	TCGA;ICGC	1.204	Down-regulation
AGC_PKC_PKCd_PRKCQ_ST	P15311	EZR	Q04759	PRKCQ	T567	R569Q	569	Missense	proximal	2	no	1.525	1.288	PhosphoSitePlus	TCGA;ICGC;COSMIC	1.204	Down-regulation
AGC_PKC_PKCd_PRKCQ_ST	Q04759	PRKCQ	Q04759	PRKCQ	S657	P653L	653	Missense	distal	-4	no	1.776	1.758	EPSD	TCGA;ICGC;COSMIC	1.204	Down-regulation
AGC_PKC_PKCd_PRKCQ_ST	Q04759	PRKCQ	Q04759	PRKCQ	S657	N663S	663	Missense	distal	6	no	1.776	1.788	EPSD	TCGA;ICGC;COSMIC	1.204	Up-regulation
AGC_PKC_PKCd_PRKCQ_ST	Q04759	PRKCQ	Q04759	PRKCQ	S657	R652W	652	Missense	distal	-5	no	1.776	1.514	EPSD	TCGA;ICGC;COSMIC	1.204	Down-regulation
AGC_PKC_PKCd_PRKCQ_ST	Q04759	PRKCQ	Q04759	PRKCQ	S695	E702G	702	Missense	distal	7	no	1.753	1.758	EPSD	TCGA;ICGC;COSMIC	1.204	Up-regulation
AGC_PKC_PKCd_PRKCQ_ST	Q04759	PRKCQ	Q04759	PRKCQ	S695	S695F	695	Missense	central	0	yes	1.753	0.000	EPSD	TCGA;ICGC;COSMIC	1.204	Loss
AGC_PKC_PKCd_PRKCQ_ST	Q04759	PRKCQ	Q04759	PRKCQ	S695	G700R	700	Missense	distal	5	no	1.753	1.784	EPSD	TCGA;ICGC;COSMIC	1.204	Up-regulation
AGC_PKC_PKCd_PRKCQ_ST	Q04759	PRKCQ	Q04759	PRKCQ	S695	N689D	689	Missense	distal	-6	no	1.753	1.789	EPSD	TCGA;ICGC;COSMIC	1.204	Up-regulation
AGC_PKC_PKCd_PRKCQ_ST	Q04759	PRKCQ	Q04759	PRKCQ	S706	E702G	702	Missense	distal	-4	no	1.770	1.772	EPSD	TCGA;ICGC;COSMIC	1.204	Up-regulation
AGC_PKC_PKCd_PRKCQ_ST	Q04759	PRKCQ	Q04759	PRKCQ	S706	R703W	703	Missense	distal	-3	no	1.770	0.458	EPSD	TCGA;ICGC;COSMIC	1.204	Loss
AGC_PKC_PKCd_PRKCQ_ST	Q04759	PRKCQ	Q04759	PRKCQ	S706	G700R	700	Missense	distal	-6	no	1.770	1.524	EPSD	TCGA;ICGC;COSMIC	1.204	Down-regulation
AGC_PKC_PKCd_PRKCQ_ST	P35568	IRS1	Q04759	PRKCQ	S24	R20C	20	Missense	distal	-4	no	1.549	1.491	EPSD	TCGA;ICGC;COSMIC	1.204	Down-regulation
AGC_PKC_PKCd_PRKCQ_ST	P35568	IRS1	Q04759	PRKCQ	S24	R20H	20	Missense	distal	-4	no	1.549	1.499	EPSD	TCGA;ICGC	1.204	Down-regulation
AGC_PKC_PKCd_PRKCQ_ST	P35568	IRS1	Q04759	PRKCQ	S36	E37K	37	Missense	proximal	1	no	1.488	1.497	EPSD	TCGA;ICGC;COSMIC;GDSC;CCLE	1.204	Up-regulation
AGC_PKC_PKCd_PRKCQ_ST	P35568	IRS1	Q04759	PRKCQ	S36	A42V	42	Missense	distal	6	no	1.488	1.468	EPSD	TCGA;ICGC;COSMIC	1.204	Down-regulation
AGC_PKC_PKCd_PRKCQ_ST	P35568	IRS1	Q04759	PRKCQ	S36	A42T	42	Missense	distal	6	no	1.488	1.468	EPSD	TCGA;ICGC;COSMIC	1.204	Down-regulation
AGC_PKC_PKCd_PRKCQ_ST	P35568	IRS1	Q04759	PRKCQ	S36	S36N	36	Missense	central	0	yes	1.488	0.000	EPSD	TCGA;ICGC;COSMIC	1.204	Loss
AGC_PKC_PKCd_PRKCQ_ST	P35568	IRS1	Q04759	PRKCQ	S36	R33C	33	Missense	distal	-3	no	1.488	0.188	EPSD	TCGA;ICGC;COSMIC	1.204	Loss
AGC_PKC_PKCd_PRKCQ_ST	P35568	IRS1	Q04759	PRKCQ	S193	V195M	195	Missense	proximal	2	no	1.310	1.382	EPSD	TCGA;ICGC;COSMIC	1.204	Up-regulation
AGC_PKC_PKCd_PRKCQ_ST	P35568	IRS1	Q04759	PRKCQ	S268	E263K	263	Missense	distal	-5	no	1.946	2.158	EPSD	TCGA;ICGC;COSMIC	1.204	Up-regulation
AGC_PKC_PKCd_PRKCQ_ST	P35568	IRS1	Q04759	PRKCQ	S268	K269N	269	Missense	proximal	1	no	1.946	1.940	EPSD	TCGA;ICGC;COSMIC	1.204	Down-regulation
AGC_PKC_PKCd_PRKCQ_ST	P35568	IRS1	Q04759	PRKCQ	S268	P266S	266	Missense	proximal	-2	no	1.946	1.874	EPSD	TCGA;ICGC;COSMIC	1.204	Down-regulation
AGC_PKC_PKCd_PRKCQ_ST	P35568	IRS1	Q04759	PRKCQ	S268	S261I	261	Missense	distal	-7	no	1.946	1.950	EPSD	TCGA;ICGC;COSMIC	1.204	Up-regulation
AGC_PKC_PKCd_PRKCQ_ST	P35568	IRS1	Q04759	PRKCQ	S268	N275S	275	Missense	distal	7	no	1.946	1.941	EPSD	TCGA;ICGC;COSMIC	1.204	Down-regulation
AGC_PKC_PKCd_PRKCQ_ST	P35568	IRS1	Q04759	PRKCQ	S270	E263K	263	Missense	distal	-7	no	2.580	2.563	EPSD	TCGA;ICGC;COSMIC	1.204	Down-regulation
AGC_PKC_PKCd_PRKCQ_ST	P35568	IRS1	Q04759	PRKCQ	S270	K269N	269	Missense	proximal	-1	no	2.580	2.575	EPSD	TCGA;ICGC;COSMIC	1.204	Down-regulation
AGC_PKC_PKCd_PRKCQ_ST	P35568	IRS1	Q04759	PRKCQ	S270	P266S	266	Missense	distal	-4	no	2.580	2.588	EPSD	TCGA;ICGC;COSMIC	1.204	Up-regulation
AGC_PKC_PKCd_PRKCQ_ST	P35568	IRS1	Q04759	PRKCQ	S270	C276F	276	Missense	distal	6	no	2.580	2.586	EPSD	TCGA;ICGC;COSMIC	1.204	Up-regulation
AGC_PKC_PKCd_PRKCQ_ST	P35568	IRS1	Q04759	PRKCQ	S270	N275S	275	Missense	distal	5	no	2.580	2.582	EPSD	TCGA;ICGC;COSMIC	1.204	Up-regulation
AGC_PKC_PKCd_PRKCQ_ST	P35568	IRS1	Q04759	PRKCQ	S272	K269N	269	Missense	distal	-3	no	1.399	0.635	EPSD	TCGA;ICGC;COSMIC	1.204	Loss
AGC_PKC_PKCd_PRKCQ_ST	P35568	IRS1	Q04759	PRKCQ	S272	P266S	266	Missense	distal	-6	no	1.399	1.389	EPSD	TCGA;ICGC;COSMIC	1.204	Down-regulation
AGC_PKC_PKCd_PRKCQ_ST	P35568	IRS1	Q04759	PRKCQ	S272	C276F	276	Missense	distal	4	no	1.399	1.427	EPSD	TCGA;ICGC;COSMIC	1.204	Up-regulation
AGC_PKC_PKCd_PRKCQ_ST	P35568	IRS1	Q04759	PRKCQ	S272	N275S	275	Missense	distal	3	no	1.399	1.405	EPSD	TCGA;ICGC;COSMIC	1.204	Up-regulation
AGC_PKC_PKCd_PRKCQ_ST	P35568	IRS1	Q04759	PRKCQ	S307	A314G	314	Missense	distal	7	no	1.791	1.823	EPSD	TCGA;ICGC;COSMIC	1.204	Up-regulation
AGC_PKC_PKCd_PRKCQ_ST	P35568	IRS1	Q04759	PRKCQ	S323	R327H	327	Missense	distal	4	no	1.628	1.478	EPSD	TCGA;ICGC	1.204	Down-regulation
AGC_PKC_PKCd_PRKCQ_ST	P35568	IRS1	Q04759	PRKCQ	S323	A328T	328	Missense	distal	5	no	1.628	1.621	EPSD	TCGA;ICGC;COSMIC	1.204	Down-regulation
AGC_PKC_PKCd_PRKCQ_ST	P35568	IRS1	Q04759	PRKCQ	S323	S330N	330	Missense	distal	7	no	1.628	1.634	EPSD	TCGA;ICGC;COSMIC	1.204	Up-regulation
AGC_PKC_PKCd_PRKCQ_ST	P35568	IRS1	Q04759	PRKCQ	S323	S323A	323	Missense	central	0	yes	1.628	0.000	EPSD	TCGA;ICGC;COSMIC	1.204	Loss
AGC_PKC_PKCd_PRKCQ_ST	P35568	IRS1	Q04759	PRKCQ	S323	P321L	321	Missense	proximal	-2	no	1.628	1.414	EPSD	TCGA;ICGC;COSMIC	1.204	Down-regulation
AGC_PKC_PKCd_PRKCQ_ST	P35568	IRS1	Q04759	PRKCQ	S330	R327H	327	Missense	distal	-3	no	1.440	0.327	EPSD	TCGA;ICGC	1.204	Loss
AGC_PKC_PKCd_PRKCQ_ST	P35568	IRS1	Q04759	PRKCQ	S330	A328T	328	Missense	proximal	-2	no	1.440	1.427	EPSD	TCGA;ICGC;COSMIC	1.204	Down-regulation
AGC_PKC_PKCd_PRKCQ_ST	P35568	IRS1	Q04759	PRKCQ	S330	S330N	330	Missense	central	0	yes	1.440	0.000	EPSD	TCGA;ICGC;COSMIC	1.204	Loss
AGC_PKC_PKCd_PRKCQ_ST	P35568	IRS1	Q04759	PRKCQ	S330	S323A	323	Missense	distal	-7	no	1.440	1.439	EPSD	TCGA;ICGC;COSMIC	1.204	Down-regulation
AGC_PKC_PKCd_PRKCQ_ST	P35568	IRS1	Q04759	PRKCQ	S341	T335I	335	Missense	distal	-6	no	2.052	2.050	EPSD	TCGA;ICGC;COSMIC	1.204	Down-regulation
AGC_PKC_PKCd_PRKCQ_ST	P35568	IRS1	Q04759	PRKCQ	S341	R338H	338	Missense	distal	-3	no	2.052	0.939	EPSD	TCGA;ICGC;COSMIC	1.204	Loss
AGC_PKC_PKCd_PRKCQ_ST	P35568	IRS1	Q04759	PRKCQ	S341	R338C	338	Missense	distal	-3	no	2.052	0.753	EPSD	TCGA;ICGC;COSMIC	1.204	Loss
AGC_PKC_PKCd_PRKCQ_ST	P35568	IRS1	Q04759	PRKCQ	S341	P346H	346	Missense	distal	5	no	2.052	2.048	EPSD	TCGA;ICGC	1.204	Down-regulation
AGC_PKC_PKCd_PRKCQ_ST	P35568	IRS1	Q04759	PRKCQ	S362	A363D	363	Missense	proximal	1	no	1.815	1.808	EPSD	TCGA;ICGC;COSMIC	1.204	Down-regulation
AGC_PKC_PKCd_PRKCQ_ST	P35568	IRS1	Q04759	PRKCQ	S362	A356T	356	Missense	distal	-6	no	1.815	1.863	EPSD	TCGA;ICGC;COSMIC	1.204	Up-regulation
AGC_PKC_PKCd_PRKCQ_ST	P35568	IRS1	Q04759	PRKCQ	S362	A363T	363	Missense	proximal	1	no	1.815	1.811	EPSD	TCGA;ICGC;COSMIC	1.204	Down-regulation
AGC_PKC_PKCd_PRKCQ_ST	P35568	IRS1	Q04759	PRKCQ	S362	R360W	360	Missense	proximal	-2	no	1.815	1.101	EPSD	TCGA;ICGC;CCLE	1.204	Loss
AGC_PKC_PKCd_PRKCQ_ST	P35568	IRS1	Q04759	PRKCQ	S362	H359R	359	Missense	distal	-3	no	1.815	2.928	EPSD	TCGA;ICGC	1.204	Up-regulation
AGC_PKC_PKCd_PRKCQ_ST	P35568	IRS1	Q04759	PRKCQ	S383	P389L	389	Missense	distal	6	no	1.259	1.242	EPSD	TCGA;ICGC;COSMIC	1.204	Down-regulation
AGC_PKC_PKCd_PRKCQ_ST	P35568	IRS1	Q04759	PRKCQ	S383	R381H	381	Missense	proximal	-2	no	1.259	0.656	EPSD	TCGA	1.204	Loss
AGC_PKC_PKCd_PRKCQ_ST	P35568	IRS1	Q04759	PRKCQ	S383	P384H	384	Missense	proximal	1	no	1.259	1.257	EPSD	TCGA;ICGC;COSMIC	1.204	Down-regulation
AGC_PKC_PKCd_PRKCQ_ST	P35568	IRS1	Q04759	PRKCQ	S383	P378S	378	Missense	distal	-5	no	1.259	1.261	EPSD	TCGA;ICGC;COSMIC	1.204	Up-regulation
AGC_PKC_PKCd_PRKCQ_ST	P35568	IRS1	Q04759	PRKCQ	S412	R411Q	411	Missense	proximal	-1	no	1.494	1.484	EPSD	TCGA;ICGC	1.204	Down-regulation
AGC_PKC_PKCd_PRKCQ_ST	P35568	IRS1	Q04759	PRKCQ	S413	R411Q	411	Missense	proximal	-2	no	2.138	1.481	EPSD	TCGA;ICGC	1.204	Down-regulation
AGC_PKC_PKCd_PRKCQ_ST	P35568	IRS1	Q04759	PRKCQ	S441	F438V	438	Missense	distal	-3	no	1.831	1.448	EPSD	TCGA;ICGC;COSMIC	1.204	Down-regulation
AGC_PKC_PKCd_PRKCQ_ST	P35568	IRS1	Q04759	PRKCQ	S441	V445I	445	Missense	distal	4	no	1.831	1.855	EPSD	TCGA;ICGC;COSMIC	1.204	Up-regulation
AGC_PKC_PKCd_PRKCQ_ST	P35568	IRS1	Q04759	PRKCQ	S441	R443H	443	Missense	proximal	2	no	1.831	1.605	EPSD	TCGA;ICGC	1.204	Down-regulation
AGC_PKC_PKCd_PRKCQ_ST	P35568	IRS1	Q04759	PRKCQ	T525	R520W	520	Missense	distal	-5	no	1.703	1.442	EPSD	TCGA;ICGC;COSMIC	1.204	Down-regulation
AGC_PKC_PKCd_PRKCQ_ST	P35568	IRS1	Q04759	PRKCQ	T525	R522Q	522	Missense	distal	-3	no	1.703	0.475	EPSD	TCGA;ICGC;COSMIC	1.204	Loss
AGC_PKC_PKCd_PRKCQ_ST	P35568	IRS1	Q04759	PRKCQ	T525	R520Q	520	Missense	distal	-5	no	1.703	1.468	EPSD	TCGA;ICGC;COSMIC	1.204	Down-regulation
AGC_PKC_PKCd_PRKCQ_ST	P35568	IRS1	Q04759	PRKCQ	S527	R520W	520	Missense	distal	-7	no	1.950	1.974	EPSD	TCGA;ICGC;COSMIC	1.204	Up-regulation
AGC_PKC_PKCd_PRKCQ_ST	P35568	IRS1	Q04759	PRKCQ	S527	R522Q	522	Missense	distal	-5	no	1.950	1.714	EPSD	TCGA;ICGC;COSMIC	1.204	Down-regulation
AGC_PKC_PKCd_PRKCQ_ST	P35568	IRS1	Q04759	PRKCQ	S527	R520Q	520	Missense	distal	-7	no	1.950	1.971	EPSD	TCGA;ICGC;COSMIC	1.204	Up-regulation
AGC_PKC_PKCd_PRKCQ_ST	P35568	IRS1	Q04759	PRKCQ	S574	S581Y	581	Missense	distal	7	no	1.323	1.334	EPSD	TCGA;ICGC;COSMIC	1.204	Up-regulation
AGC_PKC_PKCd_PRKCQ_ST	P35568	IRS1	Q04759	PRKCQ	S574	P569L	569	Missense	distal	-5	no	1.323	1.240	EPSD	TCGA;ICGC;COSMIC	1.204	Down-regulation
AGC_PKC_PKCd_PRKCQ_ST	P35568	IRS1	Q04759	PRKCQ	S603	H607R	607	Missense	distal	4	no	2.139	2.289	EPSD	TCGA;ICGC	1.204	Up-regulation
AGC_PKC_PKCd_PRKCQ_ST	P35568	IRS1	Q04759	PRKCQ	S603	R600C	600	Missense	distal	-3	no	2.139	0.839	EPSD	TCGA;ICGC;COSMIC	1.204	Loss
AGC_PKC_PKCd_PRKCQ_ST	P35568	IRS1	Q04759	PRKCQ	S792	R797C	797	Missense	distal	5	no	1.315	1.285	EPSD	TCGA;ICGC;COSMIC	1.204	Down-regulation
AGC_PKC_PKCd_PRKCQ_ST	P35568	IRS1	Q04759	PRKCQ	S862	A856T	856	Missense	distal	-6	no	1.309	1.357	EPSD	TCGA;ICGC;COSMIC	1.204	Up-regulation
AGC_PKC_PKCd_PRKCQ_ST	P35568	IRS1	Q04759	PRKCQ	S862	R857W	857	Missense	distal	-5	no	1.309	1.047	EPSD	TCGA;ICGC;COSMIC	1.204	Loss
AGC_PKC_PKCd_PRKCQ_ST	P35568	IRS1	Q04759	PRKCQ	S869	E876Q	876	Missense	distal	7	no	1.781	1.759	EPSD	TCGA;ICGC;COSMIC	1.204	Down-regulation
AGC_PKC_PKCd_PRKCQ_ST	P35568	IRS1	Q04759	PRKCQ	S1000	S1005L	1005	Missense	distal	5	no	1.727	1.721	EPSD	TCGA;ICGC	1.204	Down-regulation
AGC_PKC_PKCd_PRKCQ_ST	P35568	IRS1	Q04759	PRKCQ	S1084	R1081H	1081	Missense	distal	-3	no	1.829	0.716	EPSD	TCGA;ICGC;COSMIC	1.204	Loss
AGC_PKC_PKCd_PRKCQ_ST	P35568	IRS1	Q04759	PRKCQ	S1084	R1089C	1089	Missense	distal	5	no	1.829	1.800	EPSD	TCGA;ICGC;COSMIC	1.204	Down-regulation
AGC_PKC_PKCd_PRKCQ_ST	P35568	IRS1	Q04759	PRKCQ	S1222	S1223G	1223	Missense	proximal	1	no	1.283	1.279	EPSD	TCGA;ICGC;COSMIC	1.204	Down-regulation
AGC_PKC_PKCd_PRKCQ_ST	P35568	IRS1	Q04759	PRKCQ	S1223	S1223G	1223	Missense	central	0	yes	2.309	0.000	EPSD	TCGA;ICGC;COSMIC	1.204	Loss
AGC_PKC_PKCd_PRKCQ_ST	Q3V6T2	CCDC88A	Q04759	PRKCQ	S230	L224V	224	Missense	distal	-6	no	1.221	1.238	EPSD	TCGA;ICGC;COSMIC	1.204	Up-regulation
AGC_PKC_PKCd_PRKCQ_ST	Q3V6T2	CCDC88A	Q04759	PRKCQ	S230	H226Y	226	Missense	distal	-4	no	1.221	1.216	EPSD	TCGA;ICGC;COSMIC	1.204	Down-regulation
AGC_PKC_PKCd_PRKCQ_ST	Q3V6T2	CCDC88A	Q04759	PRKCQ	S245	L249V	249	Missense	distal	4	no	2.334	2.317	EPSD	TCGA;ICGC;COSMIC	1.204	Down-regulation
AGC_PKC_PKCd_PRKCQ_ST	Q3V6T2	CCDC88A	Q04759	PRKCQ	S1675	H1668Y	1668	Missense	distal	-7	no	1.302	1.304	EPSD	TCGA;ICGC;COSMIC	1.204	Up-regulation
AGC_PKC_PKCd_PRKCQ_ST	Q3V6T2	CCDC88A	Q04759	PRKCQ	S1675	H1668R	1668	Missense	distal	-7	no	1.302	1.282	EPSD	TCGA;ICGC;COSMIC	1.204	Down-regulation
AGC_PKC_PKCd_PRKCQ_ST	O95267	RASGRP1	Q04759	PRKCQ	T184	S180Y	180	Missense	distal	-4	no	1.751	1.732	PhosphoSitePlus	TCGA;ICGC	1.204	Down-regulation
AGC_PKC_PKCd_PRKCQ_ST	O95267	RASGRP1	Q04759	PRKCQ	T184	K188Q	188	Missense	distal	4	no	1.751	1.661	PhosphoSitePlus	TCGA;ICGC;COSMIC	1.204	Down-regulation
AGC_PKC_PKCd_PRKCQ_ST	O95267	RASGRP1	Q04759	PRKCQ	T184	Q185R	185	Missense	proximal	1	no	1.751	1.767	PhosphoSitePlus	TCGA;ICGC;COSMIC	1.204	Up-regulation
AGC_PKC_PKCd_PRKCQ_ST	O95267	RASGRP1	Q04759	PRKCQ	T184	K188R	188	Missense	distal	4	no	1.751	1.814	PhosphoSitePlus	TCGA;ICGC	1.204	Up-regulation
AGC_PKC_PKCd_PRKCQ_ST	O95267	RASGRP1	Q04759	PRKCQ	S198	K194T	194	Missense	distal	-4	no	2.197	2.157	EPSD	TCGA;ICGC;COSMIC	1.204	Down-regulation
AGC_PKC_PKCd_PRKCQ_ST	O95267	RASGRP1	Q04759	PRKCQ	S198	R195Q	195	Missense	distal	-3	no	2.197	0.969	EPSD	TCGA;ICGC;COSMIC;GDSC	1.204	Loss
AGC_PKC_PKCd_PRKCQ_ST	O95267	RASGRP1	Q04759	PRKCQ	S661	S661Y	661	Missense	central	0	yes	1.503	0.000	EPSD	TCGA;ICGC;COSMIC;GDSC;CCLE	1.204	Loss
AGC_PKC_PKCd_PRKCQ_ST	O95267	RASGRP1	Q04759	PRKCQ	S661	V655M	655	Missense	distal	-6	no	1.503	1.428	EPSD	TCGA;ICGC;COSMIC	1.204	Down-regulation
AGC_PKC_PKCd_PRKCQ_ST	O95267	RASGRP1	Q04759	PRKCQ	S732	E739K	739	Missense	distal	7	no	1.220	1.171	EPSD	TCGA;ICGC;COSMIC	1.204	Loss
AGC_PKC_PKCd_PRKCQ_ST	O95267	RASGRP1	Q04759	PRKCQ	S732	E728K	728	Missense	distal	-4	no	1.220	1.254	EPSD	TCGA;ICGC;COSMIC	1.204	Up-regulation
AGC_PKC_PKCd_PRKCQ_ST	Q9BXL7	CARD11	Q04759	PRKCQ	S68	L66R	66	Missense	proximal	-2	no	0.596	1.346	EPSD	TCGA;ICGC	1.204	Gain
AGC_PKC_PKCd_PRKCQ_ST	Q9BXL7	CARD11	Q04759	PRKCQ	S116	E121Q	121	Missense	distal	5	no	2.631	2.637	EPSD	TCGA;ICGC;COSMIC	1.204	Up-regulation
AGC_PKC_PKCd_PRKCQ_ST	Q9BXL7	CARD11	Q04759	PRKCQ	S116	P111H	111	Missense	distal	-5	no	2.631	2.602	EPSD	TCGA;ICGC;COSMIC	1.204	Down-regulation
AGC_PKC_PKCd_PRKCQ_ST	Q9BXL7	CARD11	Q04759	PRKCQ	S116	R113W	113	Missense	distal	-3	no	2.631	1.319	EPSD	TCGA;ICGC;COSMIC	1.204	Down-regulation
AGC_PKC_PKCd_PRKCQ_ST	Q9BXL7	CARD11	Q04759	PRKCQ	S439	S433R	433	Missense	distal	-6	no	2.329	2.157	EPSD	TCGA;ICGC;COSMIC	1.204	Down-regulation
AGC_PKC_PKCd_PRKCQ_ST	Q9BXL7	CARD11	Q04759	PRKCQ	S439	S433T	433	Missense	distal	-6	no	2.329	2.408	EPSD	TCGA;ICGC;COSMIC	1.204	Up-regulation
AGC_PKC_PKCd_PRKCQ_ST	Q9BXL7	CARD11	Q04759	PRKCQ	S512	R518Q	518	Missense	distal	6	no	1.722	1.683	EPSD	TCGA;ICGC;COSMIC	1.204	Down-regulation
AGC_PKC_PKCd_PRKCQ_ST	Q9BXL7	CARD11	Q04759	PRKCQ	S520	G526R	526	Missense	distal	6	no	2.190	2.241	EPSD	TCGA;ICGC;COSMIC;GDSC;CCLE	1.204	Up-regulation
AGC_PKC_PKCd_PRKCQ_ST	Q9BXL7	CARD11	Q04759	PRKCQ	S520	F522V	522	Missense	proximal	2	no	2.190	2.119	EPSD	TCGA;ICGC;COSMIC	1.204	Down-regulation
AGC_PKC_PKCd_PRKCQ_ST	Q9BXL7	CARD11	Q04759	PRKCQ	S520	R518Q	518	Missense	proximal	-2	no	2.190	1.533	EPSD	TCGA;ICGC;COSMIC	1.204	Down-regulation
AGC_PKC_PKCd_PRKCQ_ST	Q9BXL7	CARD11	Q04759	PRKCQ	S585	H583R	583	Missense	proximal	-2	no	0.670	1.273	EPSD	TCGA;ICGC;COSMIC	1.204	Gain
AGC_PKC_PKCd_PRKCQ_ST	Q9BXL7	CARD11	Q04759	PRKCQ	T586	H583R	583	Missense	distal	-3	no	0.346	1.459	EPSD	TCGA;ICGC;COSMIC	1.204	Gain
AGC_PKC_PKCd_PRKCQ_ST	Q9BXL7	CARD11	Q04759	PRKCQ	S610	E607K	607	Missense	distal	-3	no	1.052	2.069	EPSD	TCGA;ICGC;COSMIC	1.204	Gain
AGC_PKC_PKCd_PRKCQ_ST	Q9BXL7	CARD11	Q04759	PRKCQ	S644	M639K	639	Missense	distal	-5	no	2.782	2.928	EPSD	TCGA	1.204	Up-regulation
AGC_PKC_PKCd_PRKCQ_ST	Q9BXL7	CARD11	Q04759	PRKCQ	S644	F640L	640	Missense	distal	-4	no	2.782	2.773	EPSD	TCGA;ICGC;COSMIC	1.204	Down-regulation
AGC_PKC_PKCd_PRKCQ_ST	Q9BXL7	CARD11	Q04759	PRKCQ	S644	S644Y	644	Missense	central	0	yes	2.782	0.000	EPSD	TCGA;ICGC	1.204	Loss
AGC_PKC_PKCd_PRKCQ_ST	Q9BXL7	CARD11	Q04759	PRKCQ	S652	S652L	652	Missense	central	0	yes	1.778	0.000	EPSD	TCGA;ICGC;COSMIC;GDSC;CCLE	1.204	Loss
AGC_PKC_PKCd_PRKCQ_ST	Q9BXL7	CARD11	Q04759	PRKCQ	S652	G657E	657	Missense	distal	5	no	1.778	1.779	EPSD	TCGA;ICGC;COSMIC	1.204	Up-regulation
AGC_PKC_PKCd_PRKCQ_ST	Q9BXL7	CARD11	Q04759	PRKCQ	S886	R884W	884	Missense	proximal	-2	no	1.869	1.155	EPSD	TCGA;ICGC;COSMIC	1.204	Loss
AGC_PKC_PKCd_PRKCQ_ST	Q9BXL7	CARD11	Q04759	PRKCQ	S886	R888C	888	Missense	proximal	2	no	1.869	1.605	EPSD	TCGA;ICGC;COSMIC	1.204	Down-regulation
AGC_PKC_PKCd_PRKCQ_ST	Q9BXL7	CARD11	Q04759	PRKCQ	S923	R918W	918	Missense	distal	-5	no	2.375	2.113	EPSD	TCGA;ICGC;COSMIC	1.204	Down-regulation
AGC_PKC_PKCd_PRKCQ_ST	Q9BXL7	CARD11	Q04759	PRKCQ	S923	P926L	926	Missense	distal	3	no	2.375	2.369	EPSD	TCGA;ICGC;COSMIC	1.204	Down-regulation
AGC_PKC_PKCd_PRKCQ_ST	Q9BXL7	CARD11	Q04759	PRKCQ	T1020	Q1018R	1018	Missense	proximal	-2	no	0.671	1.327	EPSD	TCGA;ICGC;COSMIC	1.204	Gain
AGC_PKC_PKCd_PRKCQ_ST	P10588	NR2F6	Q04759	PRKCQ	S83	I84V	84	Missense	proximal	1	no	1.324	1.321	PhosphoSitePlus	TCGA;ICGC;COSMIC	1.204	Down-regulation
AGC_PKC_PKCd_PRKCQ_ST	P10588	NR2F6	Q04759	PRKCQ	S89	S94F	94	Missense	distal	5	no	2.271	2.270	EPSD	TCGA;ICGC;COSMIC	1.204	Down-regulation
AGC_PKC_PKCd_PRKCQ_ST	P10588	NR2F6	Q04759	PRKCQ	S89	R96C	96	Missense	distal	7	no	2.271	2.377	EPSD	TCGA;ICGC;COSMIC;GDSC	1.204	Up-regulation
AGC_PKC_PKCd_PRKCQ_ST	P10588	NR2F6	Q04759	PRKCQ	S89	S94Y	94	Missense	distal	5	no	2.271	2.268	EPSD	TCGA;ICGC;COSMIC	1.204	Down-regulation
AGC_PKC_PKCd_PRKCQ_ST	P10588	NR2F6	Q04759	PRKCQ	S89	I84V	84	Missense	distal	-5	no	2.271	2.243	EPSD	TCGA;ICGC;COSMIC	1.204	Down-regulation
AGC_PKC_PKCd_PRKCQ_ST	P01116	KRAS	Q04759	PRKCQ	S65	E62K	62	Missense	distal	-3	no	0.260	1.277	EPSD	TCGA;ICGC;COSMIC	1.204	Gain
AGC_PKC_PKCd_PRKCQ_ST	P01116	KRAS	Q04759	PRKCQ	S172	K176Q	176	Missense	distal	4	no	2.221	2.131	EPSD	TCGA;ICGC;COSMIC	1.204	Down-regulation
AGC_PKC_PKCd_PRKCQ_ST	P15407	FOSL1	Q04759	PRKCQ	S251	R249P	249	Missense	proximal	-2	no	1.542	1.006	EPSD	TCGA;COSMIC	1.204	Loss
AGC_PKC_PKCd_PRKCQ_ST	P15407	FOSL1	Q04759	PRKCQ	S251	H248N	248	Missense	distal	-3	no	1.542	1.474	EPSD	TCGA;COSMIC	1.204	Down-regulation
AGC_PKC_PKCd_PRKCQ_ST	P15407	FOSL1	Q04759	PRKCQ	S251	A247T	247	Missense	distal	-4	no	1.542	1.522	EPSD	TCGA;COSMIC	1.204	Down-regulation
AGC_PKC_PKCd_PRKCQ_ST	P15407	FOSL1	Q04759	PRKCQ	S251	G256R	256	Missense	distal	5	no	1.542	1.573	EPSD	TCGA;COSMIC	1.204	Up-regulation
AGC_PKC_PKCd_PRKCQ_ST	P15407	FOSL1	Q04759	PRKCQ	S251	R249C	249	Missense	proximal	-2	no	1.542	0.838	EPSD	TCGA;COSMIC	1.204	Loss
AGC_PKC_PKCd_PRKCQ_ST	P15407	FOSL1	Q04759	PRKCQ	S252	R249P	249	Missense	distal	-3	no	2.235	1.249	EPSD	TCGA;COSMIC	1.204	Down-regulation
AGC_PKC_PKCd_PRKCQ_ST	P15407	FOSL1	Q04759	PRKCQ	S252	H248N	248	Missense	distal	-4	no	2.235	2.233	EPSD	TCGA;COSMIC	1.204	Down-regulation
AGC_PKC_PKCd_PRKCQ_ST	P15407	FOSL1	Q04759	PRKCQ	S252	A247T	247	Missense	distal	-5	no	2.235	2.206	EPSD	TCGA;COSMIC	1.204	Down-regulation
AGC_PKC_PKCd_PRKCQ_ST	P15407	FOSL1	Q04759	PRKCQ	S252	G256R	256	Missense	distal	4	no	2.235	2.418	EPSD	TCGA;COSMIC	1.204	Up-regulation
AGC_PKC_PKCd_PRKCQ_ST	P15407	FOSL1	Q04759	PRKCQ	S252	R249C	249	Missense	distal	-3	no	2.235	0.936	EPSD	TCGA;COSMIC	1.204	Loss
AGC_PKC_PKCd_PRKCQ_ST	P15407	FOSL1	Q04759	PRKCQ	S253	R249P	249	Missense	distal	-4	no	1.518	1.475	EPSD	TCGA;COSMIC	1.204	Down-regulation
AGC_PKC_PKCd_PRKCQ_ST	P15407	FOSL1	Q04759	PRKCQ	S253	H248N	248	Missense	distal	-5	no	1.518	1.501	EPSD	TCGA;COSMIC	1.204	Down-regulation
AGC_PKC_PKCd_PRKCQ_ST	P15407	FOSL1	Q04759	PRKCQ	S253	A247T	247	Missense	distal	-6	no	1.518	1.566	EPSD	TCGA;COSMIC	1.204	Up-regulation
AGC_PKC_PKCd_PRKCQ_ST	P15407	FOSL1	Q04759	PRKCQ	S253	G256R	256	Missense	distal	3	no	1.518	1.541	EPSD	TCGA;COSMIC	1.204	Up-regulation
AGC_PKC_PKCd_PRKCQ_ST	P15407	FOSL1	Q04759	PRKCQ	S253	R249C	249	Missense	distal	-4	no	1.518	1.460	EPSD	TCGA;COSMIC	1.204	Down-regulation
AGC_PKC_PKCd_PRKCQ_ST	P15407	FOSL1	Q04759	PRKCQ	S254	G256R	256	Missense	proximal	2	no	1.136	1.416	EPSD	TCGA;COSMIC	1.204	Gain
AGC_PKC_PKCd_PRKCQ_ST	P15407	FOSL1	Q04759	PRKCQ	S259	G256R	256	Missense	distal	-3	no	0.336	1.654	EPSD	TCGA;COSMIC	1.204	Gain
AGC_PKC_PKCd_PRKCQ_ST	P26038	MSN	Q04759	PRKCQ	S6	R8C	8	Missense	proximal	2	no	1.727	1.462	EPSD	TCGA;ICGC;COSMIC;GDSC;CCLE	1.204	Down-regulation
AGC_PKC_PKCd_PRKCQ_ST	P26038	MSN	Q04759	PRKCQ	S6	K3T	3	Missense	distal	-3	no	1.727	0.912	EPSD	TCGA;ICGC	1.204	Loss
AGC_PKC_PKCd_PRKCQ_ST	P26038	MSN	Q04759	PRKCQ	S56	G54S	54	Missense	proximal	-2	no	1.155	1.270	EPSD	TCGA;ICGC;COSMIC	1.204	Gain
AGC_PKC_PKCd_PRKCQ_ST	P26038	MSN	Q04759	PRKCQ	S74	D69N	69	Missense	distal	-5	no	2.000	2.044	EPSD	TCGA;ICGC;COSMIC	1.204	Up-regulation
AGC_PKC_PKCd_PRKCQ_ST	P26038	MSN	Q04759	PRKCQ	S74	A67V	67	Missense	distal	-7	no	2.000	2.007	EPSD	TCGA;ICGC	1.204	Up-regulation
AGC_PKC_PKCd_PRKCQ_ST	P26038	MSN	Q04759	PRKCQ	S144	H142R	142	Missense	proximal	-2	no	0.861	1.464	EPSD	TCGA;ICGC;COSMIC	1.204	Gain
AGC_PKC_PKCd_PRKCQ_ST	P26038	MSN	Q04759	PRKCQ	S214	I208M	208	Missense	distal	-6	no	2.190	2.139	EPSD	TCGA;ICGC;COSMIC	1.204	Down-regulation
AGC_PKC_PKCd_PRKCQ_ST	P26038	MSN	Q04759	PRKCQ	S214	S207N	207	Missense	distal	-7	no	2.190	2.191	EPSD	TCGA;ICGC;COSMIC	1.204	Up-regulation
AGC_PKC_PKCd_PRKCQ_ST	P26038	MSN	Q04759	PRKCQ	S249	D252H	252	Missense	distal	3	no	1.577	1.582	EPSD	TCGA;ICGC;COSMIC	1.204	Up-regulation
AGC_PKC_PKCd_PRKCQ_ST	P26038	MSN	Q04759	PRKCQ	S384	A386T	386	Missense	proximal	2	no	2.355	2.331	EPSD	TCGA;ICGC;COSMIC	1.204	Down-regulation
AGC_PKC_PKCd_PRKCQ_ST	P26038	MSN	Q04759	PRKCQ	S384	R381H	381	Missense	distal	-3	no	2.355	1.242	EPSD	TCGA;ICGC;COSMIC	1.204	Down-regulation
AGC_PKC_PKCd_PRKCQ_ST	P26038	MSN	Q04759	PRKCQ	S384	K388T	388	Missense	distal	4	no	2.355	2.246	EPSD	TCGA;ICGC	1.204	Down-regulation
AGC_PKC_PKCd_PRKCQ_ST	P26038	MSN	Q04759	PRKCQ	S384	S384N	384	Missense	central	0	yes	2.355	0.000	EPSD	TCGA;ICGC	1.204	Loss
AGC_PKC_PKCd_PRKCQ_ST	P26038	MSN	Q04759	PRKCQ	S440	R435Q	435	Missense	distal	-5	no	1.649	1.414	EPSD	TCGA;ICGC;COSMIC	1.204	Down-regulation
AGC_PKC_PKCd_PRKCQ_ST	P26038	MSN	Q04759	PRKCQ	S440	K438M	438	Missense	proximal	-2	no	1.649	1.272	EPSD	TCGA;ICGC;COSMIC	1.204	Down-regulation
AGC_PKC_PKCd_PRKCQ_ST	P26038	MSN	Q04759	PRKCQ	S440	Q436H	436	Missense	distal	-4	no	1.649	1.647	EPSD	TCGA;ICGC;COSMIC	1.204	Down-regulation
AGC_PKC_PKCd_PRKCQ_ST	P26038	MSN	Q04759	PRKCQ	S504	R503C	503	Missense	proximal	-1	no	1.474	1.462	EPSD	TCGA;ICGC;COSMIC	1.204	Down-regulation
AGC_PKC_PKCd_PRKCQ_ST	P26038	MSN	Q04759	PRKCQ	S504	R508C	508	Missense	distal	4	no	1.474	1.298	EPSD	TCGA;ICGC;COSMIC	1.204	Down-regulation
AGC_PKC_PKCd_PRKCQ_ST	P26038	MSN	Q04759	PRKCQ	S504	R503H	503	Missense	proximal	-1	no	1.474	1.463	EPSD	TCGA;ICGC;COSMIC	1.204	Down-regulation
AGC_PKC_PKCd_PRKCQ_ST	P26038	MSN	Q04759	PRKCQ	S504	E505K	505	Missense	proximal	1	no	1.474	1.483	EPSD	TCGA;ICGC;COSMIC	1.204	Up-regulation
AGC_PKC_PKCd_PRKCQ_ST	P26038	MSN	Q04759	PRKCQ	S536	D534Y	534	Missense	proximal	-2	no	1.722	1.826	EPSD	TCGA;ICGC;COSMIC	1.204	Up-regulation
AGC_PKC_PKCd_PRKCQ_ST	P26038	MSN	Q04759	PRKCQ	S536	A532D	532	Missense	distal	-4	no	1.722	1.707	EPSD	TCGA;ICGC;COSMIC	1.204	Down-regulation
AGC_PKC_PKCd_PRKCQ_ST	P26038	MSN	Q04759	PRKCQ	T558	R560C	560	Missense	proximal	2	no	1.471	1.206	PhosphoSitePlus	TCGA;ICGC;COSMIC	1.204	Down-regulation
AGC_PKC_PKCd_PRKCQ_ST	P26038	MSN	Q04759	PRKCQ	T558	Q561H	561	Missense	distal	3	no	1.471	1.470	PhosphoSitePlus	TCGA;ICGC;COSMIC	1.204	Down-regulation
AGC_PKC_PKCd_PRKCQ_ST	P26038	MSN	Q04759	PRKCQ	T558	K557N	557	Missense	proximal	-1	no	1.471	1.465	PhosphoSitePlus	TCGA;ICGC	1.204	Down-regulation
AGC_PKC_PKCd_PRKCQ_ST	P26038	MSN	Q04759	PRKCQ	T558	R553Q	553	Missense	distal	-5	no	1.471	1.235	PhosphoSitePlus	TCGA;ICGC	1.204	Down-regulation
AGC_PKC_PKCd_PRKCQ_ST	O43516	WIPF1	Q04759	PRKCQ	S137	A138V	138	Missense	proximal	1	no	2.250	2.242	EPSD	TCGA;ICGC;COSMIC	1.204	Down-regulation
AGC_PKC_PKCd_PRKCQ_ST	O43516	WIPF1	Q04759	PRKCQ	S137	F141L	141	Missense	distal	4	no	2.250	2.219	EPSD	TCGA;ICGC;COSMIC	1.204	Down-regulation
AGC_PKC_PKCd_PRKCQ_ST	O43516	WIPF1	Q04759	PRKCQ	S142	A138V	138	Missense	distal	-4	no	1.664	1.643	EPSD	TCGA;ICGC;COSMIC	1.204	Down-regulation
AGC_PKC_PKCd_PRKCQ_ST	O43516	WIPF1	Q04759	PRKCQ	S142	F141L	141	Missense	proximal	-1	no	1.664	1.662	EPSD	TCGA;ICGC;COSMIC	1.204	Down-regulation
AGC_PKC_PKCd_PRKCQ_ST	O43516	WIPF1	Q04759	PRKCQ	S203	R201L	201	Missense	proximal	-2	no	1.566	0.816	EPSD	TCGA;ICGC;COSMIC	1.204	Loss
AGC_PKC_PKCd_PRKCQ_ST	O43516	WIPF1	Q04759	PRKCQ	S203	R201G	201	Missense	proximal	-2	no	1.566	0.844	EPSD	TCGA;ICGC;COSMIC	1.204	Loss
AGC_PKC_PKCd_PRKCQ_ST	O43516	WIPF1	Q04759	PRKCQ	S203	R201W	201	Missense	proximal	-2	no	1.566	0.852	EPSD	TCGA;ICGC;COSMIC	1.204	Loss
AGC_PKC_PKCd_PRKCQ_ST	O43516	WIPF1	Q04759	PRKCQ	S203	S197G	197	Missense	distal	-6	no	1.566	1.641	EPSD	TCGA;ICGC;COSMIC	1.204	Up-regulation
AGC_PKC_PKCd_PRKCQ_ST	O43516	WIPF1	Q04759	PRKCQ	S203	R201Q	201	Missense	proximal	-2	no	1.566	0.910	EPSD	TCGA;ICGC;COSMIC	1.204	Loss
AGC_PKC_PKCd_PRKCQ_ST	O43516	WIPF1	Q04759	PRKCQ	S214	G216W	216	Missense	proximal	2	no	1.518	1.533	EPSD	TCGA;ICGC;COSMIC	1.204	Up-regulation
AGC_PKC_PKCd_PRKCQ_ST	O43516	WIPF1	Q04759	PRKCQ	S214	T218S	218	Missense	distal	4	no	1.518	1.543	EPSD	TCGA;ICGC;COSMIC	1.204	Up-regulation
AGC_PKC_PKCd_PRKCQ_ST	O43516	WIPF1	Q04759	PRKCQ	S214	P215L	215	Missense	proximal	1	no	1.518	1.513	EPSD	TCGA;ICGC;COSMIC	1.204	Down-regulation
AGC_PKC_PKCd_PRKCQ_ST	O43516	WIPF1	Q04759	PRKCQ	S214	P213L	213	Missense	proximal	-1	no	1.518	1.514	EPSD	TCGA;ICGC;COSMIC	1.204	Down-regulation
AGC_PKC_PKCd_PRKCQ_ST	O43516	WIPF1	Q04759	PRKCQ	S214	P213S	213	Missense	proximal	-1	no	1.518	1.519	EPSD	TCGA;ICGC;COSMIC	1.204	Up-regulation
AGC_PKC_PKCd_PRKCQ_ST	O43516	WIPF1	Q04759	PRKCQ	S214	G216E	216	Missense	proximal	2	no	1.518	1.507	EPSD	TCGA;ICGC	1.204	Down-regulation
AGC_PKC_PKCd_PRKCQ_ST	O43516	WIPF1	Q04759	PRKCQ	S214	G216R	216	Missense	proximal	2	no	1.518	1.798	EPSD	TCGA;ICGC;COSMIC	1.204	Up-regulation
AGC_PKC_PKCd_PRKCQ_ST	O43516	WIPF1	Q04759	PRKCQ	S214	Q212K	212	Missense	proximal	-2	no	1.518	1.930	EPSD	TCGA;ICGC;COSMIC	1.204	Up-regulation
AGC_PKC_PKCd_PRKCQ_ST	O43516	WIPF1	Q04759	PRKCQ	S241	S244L	244	Missense	distal	3	no	1.276	1.266	EPSD	TCGA;ICGC;COSMIC	1.204	Down-regulation
AGC_PKC_PKCd_PRKCQ_ST	O43516	WIPF1	Q04759	PRKCQ	S241	R236H	236	Missense	distal	-5	no	1.276	1.055	EPSD	TCGA;ICGC;COSMIC	1.204	Loss
AGC_PKC_PKCd_PRKCQ_ST	O43516	WIPF1	Q04759	PRKCQ	S247	P250L	250	Missense	distal	3	no	1.403	1.397	EPSD	TCGA;ICGC;COSMIC	1.204	Down-regulation
AGC_PKC_PKCd_PRKCQ_ST	O43516	WIPF1	Q04759	PRKCQ	S247	S244L	244	Missense	distal	-3	no	1.403	1.143	EPSD	TCGA;ICGC;COSMIC	1.204	Loss
AGC_PKC_PKCd_PRKCQ_ST	O43516	WIPF1	Q04759	PRKCQ	S301	A306V	306	Missense	distal	5	no	1.451	1.440	EPSD	TCGA;ICGC;COSMIC	1.204	Down-regulation
AGC_PKC_PKCd_PRKCQ_ST	O43516	WIPF1	Q04759	PRKCQ	S301	T297A	297	Missense	distal	-4	no	1.451	1.471	EPSD	TCGA;ICGC;COSMIC	1.204	Up-regulation
AGC_PKC_PKCd_PRKCQ_ST	O43516	WIPF1	Q04759	PRKCQ	S340	S343L	343	Missense	distal	3	no	1.634	1.624	EPSD	TCGA;ICGC;COSMIC	1.204	Down-regulation
AGC_PKC_PKCd_PRKCQ_ST	O43516	WIPF1	Q04759	PRKCQ	S340	R337Q	337	Missense	distal	-3	no	1.634	0.406	EPSD	TCGA;ICGC;COSMIC	1.204	Loss
AGC_PKC_PKCd_PRKCQ_ST	O43516	WIPF1	Q04759	PRKCQ	S390	R393W	393	Missense	distal	3	no	1.714	1.692	EPSD	TCGA;ICGC;GDSC;CCLE	1.204	Down-regulation
AGC_PKC_PKCd_PRKCQ_ST	O43516	WIPF1	Q04759	PRKCQ	S424	G426R	426	Missense	proximal	2	no	1.282	1.562	EPSD	TCGA;ICGC;COSMIC	1.204	Up-regulation
AGC_PKC_PKCd_PRKCQ_ST	O43516	WIPF1	Q04759	PRKCQ	S424	P429S	429	Missense	distal	5	no	1.282	1.280	EPSD	TCGA;ICGC;COSMIC	1.204	Down-regulation
AGC_PKC_PKCd_PRKCQ_ST	O43516	WIPF1	Q04759	PRKCQ	S424	P420H	420	Missense	distal	-4	no	1.282	1.276	EPSD	TCGA;ICGC;COSMIC	1.204	Down-regulation
AGC_PKC_PKCd_PRKCQ_ST	O43516	WIPF1	Q04759	PRKCQ	S434	P429S	429	Missense	distal	-5	no	1.313	1.315	EPSD	TCGA;ICGC;COSMIC	1.204	Up-regulation
AGC_PKC_PKCd_PRKCQ_ST	O43516	WIPF1	Q04759	PRKCQ	S436	D443H	443	Missense	distal	7	no	1.374	1.355	EPSD	TCGA;ICGC;COSMIC	1.204	Down-regulation
AGC_PKC_PKCd_PRKCQ_ST	O43516	WIPF1	Q04759	PRKCQ	S436	D443N	443	Missense	distal	7	no	1.374	1.357	EPSD	TCGA;ICGC	1.204	Down-regulation
AGC_PKC_PKCd_PRKCQ_ST	O43516	WIPF1	Q04759	PRKCQ	S436	P429S	429	Missense	distal	-7	no	1.374	1.377	EPSD	TCGA;ICGC;COSMIC	1.204	Up-regulation
AGC_PKC_PKCd_PRKCQ_ST	O43516	WIPF1	Q04759	PRKCQ	S488	G494C	494	Missense	distal	6	no	2.044	2.047	PhosphoSitePlus	TCGA	1.204	Up-regulation
AGC_PKC_PKCd_PRKCQ_ST	O43516	WIPF1	Q04759	PRKCQ	S488	E483K	483	Missense	distal	-5	no	2.044	2.256	PhosphoSitePlus	TCGA;ICGC;COSMIC	1.204	Up-regulation
AGC_PKC_PKCd_PRKCQ_ST	O43516	WIPF1	Q04759	PRKCQ	S488	R490Q	490	Missense	proximal	2	no	2.044	1.807	PhosphoSitePlus	TCGA;ICGC;COSMIC;CCLE	1.204	Down-regulation
AGC_PKC_PKCd_PRKCQ_ST	Q9Y4G8	RAPGEF2	Q04759	PRKCQ	S276	I270T	270	Missense	distal	-6	no	1.646	1.648	EPSD	TCGA;ICGC;COSMIC	1.204	Up-regulation
AGC_PKC_PKCd_PRKCQ_ST	Q9Y4G8	RAPGEF2	Q04759	PRKCQ	S276	I272F	272	Missense	distal	-4	no	1.646	1.656	EPSD	TCGA;ICGC;COSMIC	1.204	Up-regulation
AGC_PKC_PKCd_PRKCQ_ST	Q9Y4G8	RAPGEF2	Q04759	PRKCQ	S276	R278G	278	Missense	proximal	2	no	1.646	1.367	EPSD	TCGA;ICGC;COSMIC	1.204	Down-regulation
AGC_PKC_PKCd_PRKCQ_ST	Q9Y4G8	RAPGEF2	Q04759	PRKCQ	S478	R482I	482	Missense	distal	4	no	1.434	1.262	EPSD	TCGA;ICGC;COSMIC	1.204	Down-regulation
AGC_PKC_PKCd_PRKCQ_ST	Q9Y4G8	RAPGEF2	Q04759	PRKCQ	S478	E472D	472	Missense	distal	-6	no	1.434	1.431	EPSD	TCGA;ICGC;COSMIC	1.204	Down-regulation
AGC_PKC_PKCd_PRKCQ_ST	Q9Y4G8	RAPGEF2	Q04759	PRKCQ	S478	L477V	477	Missense	proximal	-1	no	1.434	1.433	EPSD	TCGA;ICGC	1.204	Down-regulation
AGC_PKC_PKCd_PRKCQ_ST	Q9Y4G8	RAPGEF2	Q04759	PRKCQ	S498	S501P	501	Missense	distal	3	no	1.825	1.822	EPSD	TCGA;ICGC;COSMIC	1.204	Down-regulation
AGC_PKC_PKCd_PRKCQ_ST	Q9Y4G8	RAPGEF2	Q04759	PRKCQ	S498	P503L	503	Missense	distal	5	no	1.825	1.817	EPSD	TCGA;ICGC;COSMIC	1.204	Down-regulation
AGC_PKC_PKCd_PRKCQ_ST	Q9Y4G8	RAPGEF2	Q04759	PRKCQ	S498	R499H	499	Missense	proximal	1	no	1.825	1.808	EPSD	TCGA;ICGC;COSMIC	1.204	Down-regulation
AGC_PKC_PKCd_PRKCQ_ST	Q9Y4G8	RAPGEF2	Q04759	PRKCQ	S498	I491L	491	Missense	distal	-7	no	1.825	1.826	EPSD	TCGA;ICGC;COSMIC	1.204	Up-regulation
AGC_PKC_PKCd_PRKCQ_ST	Q9Y4G8	RAPGEF2	Q04759	PRKCQ	S498	P503T	503	Missense	distal	5	no	1.825	1.817	EPSD	TCGA;ICGC;COSMIC	1.204	Down-regulation
AGC_PKC_PKCd_PRKCQ_ST	Q9Y4G8	RAPGEF2	Q04759	PRKCQ	S501	S501P	501	Missense	central	0	yes	1.840	0.000	EPSD	TCGA;ICGC;COSMIC	1.204	Loss
AGC_PKC_PKCd_PRKCQ_ST	Q9Y4G8	RAPGEF2	Q04759	PRKCQ	S501	P503L	503	Missense	proximal	2	no	1.840	1.758	EPSD	TCGA;ICGC;COSMIC	1.204	Down-regulation
AGC_PKC_PKCd_PRKCQ_ST	Q9Y4G8	RAPGEF2	Q04759	PRKCQ	S501	R499H	499	Missense	proximal	-2	no	1.840	1.237	EPSD	TCGA;ICGC;COSMIC	1.204	Down-regulation
AGC_PKC_PKCd_PRKCQ_ST	Q9Y4G8	RAPGEF2	Q04759	PRKCQ	S501	P503T	503	Missense	proximal	2	no	1.840	1.776	EPSD	TCGA;ICGC;COSMIC	1.204	Down-regulation
AGC_PKC_PKCd_PRKCQ_ST	Q9Y4G8	RAPGEF2	Q04759	PRKCQ	S579	L576W	576	Missense	distal	-3	no	1.170	1.208	EPSD	TCGA	1.204	Gain
AGC_PKC_PKCd_PRKCQ_ST	Q9Y4G8	RAPGEF2	Q04759	PRKCQ	S912	R905C	905	Missense	distal	-7	no	1.529	1.553	EPSD	TCGA;ICGC;COSMIC;CCLE	1.204	Up-regulation
AGC_PKC_PKCd_PRKCQ_ST	Q9Y4G8	RAPGEF2	Q04759	PRKCQ	S912	R909Q	909	Missense	distal	-3	no	1.529	0.301	EPSD	TCGA;ICGC;COSMIC	1.204	Loss
AGC_PKC_PKCd_PRKCQ_ST	Q9Y4G8	RAPGEF2	Q04759	PRKCQ	S912	A911S	911	Missense	proximal	-1	no	1.529	1.531	EPSD	TCGA;ICGC;COSMIC	1.204	Up-regulation
AGC_PKC_PKCd_PRKCQ_ST	Q9Y4G8	RAPGEF2	Q04759	PRKCQ	S930	R924Q	924	Missense	distal	-6	no	1.176	1.381	EPSD	TCGA;ICGC;COSMIC	1.204	Gain
AGC_PKC_PKCd_PRKCQ_ST	Q9Y4G8	RAPGEF2	Q04759	PRKCQ	S959	R957L	957	Missense	proximal	-2	no	1.710	0.959	EPSD	TCGA;ICGC;COSMIC	1.204	Loss
AGC_PKC_PKCd_PRKCQ_ST	Q9Y4G8	RAPGEF2	Q04759	PRKCQ	S959	S959C	959	Missense	central	0	yes	1.710	0.000	EPSD	TCGA;ICGC;COSMIC	1.204	Loss
AGC_PKC_PKCd_PRKCQ_ST	Q9Y4G8	RAPGEF2	Q04759	PRKCQ	S959	R957C	957	Missense	proximal	-2	no	1.710	1.006	EPSD	TCGA;ICGC;COSMIC	1.204	Loss
AGC_PKC_PKCd_PRKCQ_ST	Q9Y4G8	RAPGEF2	Q04759	PRKCQ	S959	R955W	955	Missense	distal	-4	no	1.710	1.654	EPSD	TCGA;ICGC;COSMIC	1.204	Down-regulation
AGC_PKC_PKCd_PRKCQ_ST	Q9Y4G8	RAPGEF2	Q04759	PRKCQ	S960	R957L	957	Missense	distal	-3	no	2.930	1.581	PhosphoSitePlus	TCGA;ICGC;COSMIC	1.204	Down-regulation
AGC_PKC_PKCd_PRKCQ_ST	Q9Y4G8	RAPGEF2	Q04759	PRKCQ	S960	S959C	959	Missense	proximal	-1	no	2.930	2.926	PhosphoSitePlus	TCGA;ICGC;COSMIC	1.204	Down-regulation
AGC_PKC_PKCd_PRKCQ_ST	Q9Y4G8	RAPGEF2	Q04759	PRKCQ	S960	R957C	957	Missense	distal	-3	no	2.930	1.631	PhosphoSitePlus	TCGA;ICGC;COSMIC	1.204	Down-regulation
AGC_PKC_PKCd_PRKCQ_ST	Q9Y4G8	RAPGEF2	Q04759	PRKCQ	S960	R955W	955	Missense	distal	-5	no	2.930	2.669	PhosphoSitePlus	TCGA;ICGC;COSMIC	1.204	Down-regulation
AGC_PKC_PKCd_PRKCQ_ST	Q9Y4G8	RAPGEF2	Q04759	PRKCQ	S1089	K1086Q	1086	Missense	distal	-3	no	1.308	0.497	EPSD	TCGA;ICGC;COSMIC	1.204	Loss
AGC_PKC_PKCd_PRKCQ_ST	Q9Y4G8	RAPGEF2	Q04759	PRKCQ	S1153	R1151Q	1151	Missense	proximal	-2	no	1.545	0.888	EPSD	TCGA;ICGC;COSMIC	1.204	Loss
AGC_PKC_PKCd_PRKCQ_ST	Q9Y4G8	RAPGEF2	Q04759	PRKCQ	S1153	S1152Y	1152	Missense	proximal	-1	no	1.545	1.541	EPSD	TCGA;ICGC;COSMIC	1.204	Down-regulation
AGC_PKC_PKCd_PRKCQ_ST	Q9Y4G8	RAPGEF2	Q04759	PRKCQ	S1153	S1158L	1158	Missense	distal	5	no	1.545	1.539	EPSD	TCGA;ICGC;COSMIC	1.204	Down-regulation
AGC_PKC_PKCd_PRKCQ_ST	Q9Y4G8	RAPGEF2	Q04759	PRKCQ	S1176	E1181D	1181	Missense	distal	5	no	1.864	1.862	EPSD	TCGA;ICGC;COSMIC	1.204	Down-regulation
AGC_PKC_PKCd_PRKCQ_ST	Q9Y4G8	RAPGEF2	Q04759	PRKCQ	S1176	R1172H	1172	Missense	distal	-4	no	1.864	1.814	EPSD	TCGA;ICGC;COSMIC	1.204	Down-regulation
AGC_PKC_PKCd_PRKCQ_ST	Q9Y4G8	RAPGEF2	Q04759	PRKCQ	S1248	R1246S	1246	Missense	proximal	-2	no	1.374	0.766	EPSD	TCGA;ICGC;COSMIC	1.204	Loss
AGC_PKC_PKCd_PRKCQ_ST	Q9Y4G8	RAPGEF2	Q04759	PRKCQ	S1248	C1252S	1252	Missense	distal	4	no	1.374	1.404	EPSD	TCGA;ICGC;COSMIC	1.204	Up-regulation
AGC_PKC_PKCd_PRKCQ_ST	Q9Y4G8	RAPGEF2	Q04759	PRKCQ	S1248	S1244I	1244	Missense	distal	-4	no	1.374	1.349	EPSD	TCGA;ICGC;COSMIC	1.204	Down-regulation
AGC_PKC_PKCd_PRKCQ_ST	Q9Y4G8	RAPGEF2	Q04759	PRKCQ	S1248	G1245C	1245	Missense	distal	-3	no	1.374	1.393	EPSD	TCGA;ICGC;COSMIC	1.204	Up-regulation
AGC_PKC_PKCd_PRKCQ_ST	Q9Y4G8	RAPGEF2	Q04759	PRKCQ	S1251	R1246S	1246	Missense	distal	-5	no	1.215	1.025	EPSD	TCGA;ICGC;COSMIC	1.204	Loss
AGC_PKC_PKCd_PRKCQ_ST	Q9Y4G8	RAPGEF2	Q04759	PRKCQ	S1251	C1252S	1252	Missense	proximal	1	no	1.215	1.218	EPSD	TCGA;ICGC;COSMIC	1.204	Up-regulation
AGC_PKC_PKCd_PRKCQ_ST	Q9Y4G8	RAPGEF2	Q04759	PRKCQ	S1251	S1244I	1244	Missense	distal	-7	no	1.215	1.219	EPSD	TCGA;ICGC;COSMIC	1.204	Up-regulation
AGC_PKC_PKCd_PRKCQ_ST	Q9Y4G8	RAPGEF2	Q04759	PRKCQ	S1251	G1245C	1245	Missense	distal	-6	no	1.215	1.208	EPSD	TCGA;ICGC;COSMIC	1.204	Down-regulation
AGC_PKC_PKCd_PRKCQ_ST	Q9Y4G8	RAPGEF2	Q04759	PRKCQ	S1251	D1258A	1258	Missense	distal	7	no	1.215	1.182	EPSD	TCGA;ICGC;COSMIC	1.204	Loss
AGC_PKC_PKCd_PRKCQ_ST	Q9Y4G8	RAPGEF2	Q04759	PRKCQ	S1325	A1327V	1327	Missense	proximal	2	no	1.277	1.219	EPSD	TCGA;ICGC;COSMIC	1.204	Down-regulation
AGC_PKC_PKCd_PRKCQ_ST	Q9Y4G8	RAPGEF2	Q04759	PRKCQ	S1325	A1320T	1320	Missense	distal	-5	no	1.277	1.248	EPSD	TCGA;ICGC	1.204	Down-regulation
AGC_PKC_PKCd_PRKCQ_ST	Q13191	CBLB	Q04759	PRKCQ	S277	S282I	282	Missense	distal	5	no	1.339	1.334	EPSD	TCGA;ICGC;COSMIC	1.204	Down-regulation
AGC_PKC_PKCd_PRKCQ_ST	Q13191	CBLB	Q04759	PRKCQ	S277	R272Q	272	Missense	distal	-5	no	1.339	1.103	EPSD	TCGA;ICGC;COSMIC	1.204	Loss
AGC_PKC_PKCd_PRKCQ_ST	Q13191	CBLB	Q04759	PRKCQ	S282	F285L	285	Missense	distal	3	no	1.782	1.779	PhosphoSitePlus	TCGA;ICGC;COSMIC	1.204	Down-regulation
AGC_PKC_PKCd_PRKCQ_ST	Q13191	CBLB	Q04759	PRKCQ	S282	C289F	289	Missense	distal	7	no	1.782	1.774	PhosphoSitePlus	TCGA;ICGC;COSMIC	1.204	Down-regulation
AGC_PKC_PKCd_PRKCQ_ST	Q13191	CBLB	Q04759	PRKCQ	S282	S282I	282	Missense	central	0	yes	1.782	0.000	PhosphoSitePlus	TCGA;ICGC;COSMIC	1.204	Loss
AGC_PKC_PKCd_PRKCQ_ST	Q13191	CBLB	Q04759	PRKCQ	T471	R468Q	468	Missense	distal	-3	no	1.691	0.463	EPSD	TCGA;ICGC;COSMIC	1.204	Loss
AGC_PKC_PKCd_PRKCQ_ST	Q13191	CBLB	Q04759	PRKCQ	S533	R538K	538	Missense	distal	5	no	1.241	1.231	EPSD	TCGA;ICGC;COSMIC	1.204	Down-regulation
AGC_PKC_PKCd_PRKCQ_ST	Q13191	CBLB	Q04759	PRKCQ	S533	S533F	533	Missense	central	0	yes	1.241	0.000	EPSD	TCGA;ICGC;COSMIC	1.204	Loss
AGC_PKC_PKCd_PRKCQ_ST	Q13191	CBLB	Q04759	PRKCQ	S672	Y665C	665	Missense	distal	-7	no	1.394	1.396	EPSD	TCGA;ICGC;COSMIC	1.204	Up-regulation
AGC_PKC_PKCd_PRKCQ_ST	Q13191	CBLB	Q04759	PRKCQ	S672	D666E	666	Missense	distal	-6	no	1.394	1.397	EPSD	TCGA;ICGC	1.204	Up-regulation
AGC_PKC_PKCd_PRKCQ_ST	Q13191	CBLB	Q04759	PRKCQ	S672	P674S	674	Missense	proximal	2	no	1.394	1.335	EPSD	TCGA;ICGC;COSMIC	1.204	Down-regulation
AGC_PKC_PKCd_PRKCQ_ST	Q13191	CBLB	Q04759	PRKCQ	S672	R670W	670	Missense	proximal	-2	no	1.394	0.680	EPSD	TCGA;ICGC;COSMIC	1.204	Loss
AGC_PKC_PKCd_PRKCQ_ST	Q13191	CBLB	Q04759	PRKCQ	S672	V667I	667	Missense	distal	-5	no	1.394	1.423	EPSD	TCGA;ICGC;COSMIC	1.204	Up-regulation
AGC_PKC_PKCd_PRKCQ_ST	Q13191	CBLB	Q04759	PRKCQ	S672	P674L	674	Missense	proximal	2	no	1.394	1.313	EPSD	TCGA;ICGC;COSMIC	1.204	Down-regulation
AGC_PKC_PKCd_PRKCQ_ST	Q13191	CBLB	Q04759	PRKCQ	S672	T679I	679	Missense	distal	7	no	1.394	1.391	EPSD	TCGA;ICGC	1.204	Down-regulation
AGC_PKC_PKCd_PRKCQ_ST	Q13191	CBLB	Q04759	PRKCQ	S793	N788S	788	Missense	distal	-5	no	1.494	1.543	EPSD	TCGA;ICGC;COSMIC	1.204	Up-regulation
AGC_PKC_PKCd_PRKCQ_ST	Q13191	CBLB	Q04759	PRKCQ	S800	L805I	805	Missense	distal	5	no	1.372	1.373	EPSD	TCGA;ICGC	1.204	Up-regulation
AGC_PKC_PKCd_PRKCQ_ST	Q13191	CBLB	Q04759	PRKCQ	S886	R884I	884	Missense	proximal	-2	no	1.420	0.687	EPSD	TCGA;COSMIC	1.204	Loss
AGC_PKC_PKCd_PRKCQ_ST	Q13191	CBLB	Q04759	PRKCQ	S886	T882S	882	Missense	distal	-4	no	1.420	1.449	EPSD	TCGA;COSMIC	1.204	Up-regulation
AGC_PKC_PKCd_PRKCQ_ST	Q13191	CBLB	Q04759	PRKCQ	S977	R979C	979	Missense	proximal	2	no	1.450	1.186	EPSD	TCGA;COSMIC	1.204	Loss
AGC_PKC_PKCd_PRKCQ_ST	Q5JVS0	HABP4	Q04759	PRKCQ	T375	R369H	369	Missense	distal	-6	no	1.246	1.451	PhosphoSitePlus;EPSD	TCGA;COSMIC	1.204	Up-regulation
AGC_PKC_PKCd_PRKCQ_ST	Q5JVS0	HABP4	Q04759	PRKCQ	T375	G377E	377	Missense	proximal	2	no	1.246	1.235	PhosphoSitePlus;EPSD	TCGA;COSMIC;GDSC;CCLE	1.204	Down-regulation
AGC_PKC_PKCd_PRKCQ_ST	Q9UEW8	STK39	Q04759	PRKCQ	S142	M138L	138	Missense	distal	-4	no	1.248	1.232	EPSD	TCGA;ICGC;COSMIC	1.204	Down-regulation
AGC_PKC_PKCd_PRKCQ_ST	Q9UEW8	STK39	Q04759	PRKCQ	S142	D148N	148	Missense	distal	6	no	1.248	1.257	EPSD	TCGA;ICGC;COSMIC	1.204	Up-regulation
AGC_PKC_PKCd_PRKCQ_ST	Q9UEW8	STK39	Q04759	PRKCQ	S142	S145L	145	Missense	distal	3	no	1.248	1.238	EPSD	TCGA	1.204	Down-regulation
AGC_PKC_PKCd_PRKCQ_ST	Q9UEW8	STK39	Q04759	PRKCQ	S142	G144C	144	Missense	proximal	2	no	1.248	1.263	EPSD	TCGA;ICGC;COSMIC	1.204	Up-regulation
AGC_PKC_PKCd_PRKCQ_ST	Q9UEW8	STK39	Q04759	PRKCQ	S323	P322A	322	Missense	proximal	-1	no	1.819	1.818	PhosphoSitePlus;EPSD	TCGA;ICGC;COSMIC	1.204	Down-regulation
AGC_PKC_PKCd_PRKCQ_ST	Q9UEW8	STK39	Q04759	PRKCQ	S448	Y444H	444	Missense	distal	-4	no	1.421	1.426	EPSD	TCGA;ICGC;COSMIC	1.204	Up-regulation
AGC_PKC_PKCd_PRKCQ_ST	Q9UEW8	STK39	Q04759	PRKCQ	S448	E446K	446	Missense	proximal	-2	no	1.421	1.961	EPSD	TCGA;ICGC;COSMIC	1.204	Up-regulation
AGC_PKC_PKCd_PRKCQ_ST	Q9UEW8	STK39	Q04759	PRKCQ	S448	V452M	452	Missense	distal	4	no	1.421	1.470	EPSD	TCGA;ICGC;COSMIC	1.204	Up-regulation
AGC_PKC_PKCd_PRKCQ_ST	P32942	ICAM3	Q04759	PRKCQ	S518	H513Q	513	Missense	distal	-5	no	2.100	2.086	PhosphoSitePlus	TCGA;ICGC;COSMIC	1.204	Down-regulation
AGC_PKC_PKCd_PRKCQ_ST	P32942	ICAM3	Q04759	PRKCQ	S525	T531K	531	Missense	distal	6	no	1.574	1.617	EPSD	TCGA;ICGC;COSMIC	1.204	Up-regulation
AGC_PKC_PKCd_PRKCQ_ST	P32942	ICAM3	Q04759	PRKCQ	S525	P529S	529	Missense	distal	4	no	1.574	1.560	EPSD	TCGA;ICGC;GDSC;CCLE	1.204	Down-regulation
AGC_PKC_PKCd_PRKCQ_ST	O14974	PPP1R12A	Q04759	PRKCQ	S332	S332F	332	Missense	central	0	yes	1.700	0.000	EPSD	TCGA;ICGC;COSMIC	1.204	Loss
AGC_PKC_PKCd_PRKCQ_ST	O14974	PPP1R12A	Q04759	PRKCQ	S332	N330H	330	Missense	proximal	-2	no	1.700	1.758	EPSD	TCGA;ICGC;COSMIC	1.204	Up-regulation
AGC_PKC_PKCd_PRKCQ_ST	O14974	PPP1R12A	Q04759	PRKCQ	S332	S336Y	336	Missense	distal	4	no	1.700	1.684	EPSD	TCGA;ICGC;COSMIC	1.204	Down-regulation
AGC_PKC_PKCd_PRKCQ_ST	O14974	PPP1R12A	Q04759	PRKCQ	S336	S332F	332	Missense	distal	-4	no	1.562	1.546	EPSD	TCGA;ICGC;COSMIC	1.204	Down-regulation
AGC_PKC_PKCd_PRKCQ_ST	O14974	PPP1R12A	Q04759	PRKCQ	S336	N330H	330	Missense	distal	-6	no	1.562	1.550	EPSD	TCGA;ICGC;COSMIC	1.204	Down-regulation
AGC_PKC_PKCd_PRKCQ_ST	O14974	PPP1R12A	Q04759	PRKCQ	S336	S336Y	336	Missense	central	0	yes	1.562	0.000	EPSD	TCGA;ICGC;COSMIC	1.204	Loss
AGC_PKC_PKCd_PRKCQ_ST	O14974	PPP1R12A	Q04759	PRKCQ	S353	E358K	358	Missense	distal	5	no	1.469	1.488	EPSD	TCGA;ICGC;COSMIC	1.204	Up-regulation
AGC_PKC_PKCd_PRKCQ_ST	O14974	PPP1R12A	Q04759	PRKCQ	S353	C355Y	355	Missense	proximal	2	no	1.469	1.490	EPSD	TCGA;ICGC;COSMIC	1.204	Up-regulation
AGC_PKC_PKCd_PRKCQ_ST	O14974	PPP1R12A	Q04759	PRKCQ	S353	K349N	349	Missense	distal	-4	no	1.469	1.442	EPSD	TCGA;ICGC;COSMIC	1.204	Down-regulation
AGC_PKC_PKCd_PRKCQ_ST	O14974	PPP1R12A	Q04759	PRKCQ	S353	S354I	354	Missense	proximal	1	no	1.469	1.466	EPSD	TCGA;ICGC;COSMIC	1.204	Down-regulation
AGC_PKC_PKCd_PRKCQ_ST	O14974	PPP1R12A	Q04759	PRKCQ	S353	D360V	360	Missense	distal	7	no	1.469	1.476	EPSD	TCGA;ICGC;COSMIC	1.204	Up-regulation
AGC_PKC_PKCd_PRKCQ_ST	O14974	PPP1R12A	Q04759	PRKCQ	S432	R437M	437	Missense	distal	5	no	1.559	1.536	EPSD	TCGA;ICGC;COSMIC	1.204	Down-regulation
AGC_PKC_PKCd_PRKCQ_ST	O14974	PPP1R12A	Q04759	PRKCQ	S432	W436C	436	Missense	distal	4	no	1.559	1.554	EPSD	TCGA;ICGC;COSMIC	1.204	Down-regulation
AGC_PKC_PKCd_PRKCQ_ST	O14974	PPP1R12A	Q04759	PRKCQ	S432	S432F	432	Missense	central	0	yes	1.559	0.000	EPSD	TCGA;ICGC;COSMIC	1.204	Loss
AGC_PKC_PKCd_PRKCQ_ST	O14974	PPP1R12A	Q04759	PRKCQ	S472	R475K	475	Missense	distal	3	no	1.692	1.683	EPSD	TCGA;ICGC;COSMIC	1.204	Down-regulation
AGC_PKC_PKCd_PRKCQ_ST	O14974	PPP1R12A	Q04759	PRKCQ	S477	R475K	475	Missense	proximal	-2	no	1.608	1.364	EPSD	TCGA;ICGC;COSMIC	1.204	Down-regulation
AGC_PKC_PKCd_PRKCQ_ST	O14974	PPP1R12A	Q04759	PRKCQ	S478	R475K	475	Missense	distal	-3	no	1.328	0.910	EPSD	TCGA;ICGC;COSMIC	1.204	Loss
AGC_PKC_PKCd_PRKCQ_ST	O14974	PPP1R12A	Q04759	PRKCQ	S519	R523Q	523	Missense	distal	4	no	1.411	1.259	EPSD	TCGA;GDSC	1.204	Down-regulation
AGC_PKC_PKCd_PRKCQ_ST	O14974	PPP1R12A	Q04759	PRKCQ	S520	R523Q	523	Missense	distal	3	no	1.331	1.312	EPSD	TCGA;GDSC	1.204	Down-regulation
AGC_PKC_PKCd_PRKCQ_ST	O14974	PPP1R12A	Q04759	PRKCQ	S554	R557K	557	Missense	distal	3	no	1.320	1.310	EPSD	TCGA;ICGC;COSMIC	1.204	Down-regulation
AGC_PKC_PKCd_PRKCQ_ST	O14974	PPP1R12A	Q04759	PRKCQ	S668	R667I	667	Missense	proximal	-1	no	2.668	2.655	EPSD	TCGA;ICGC;COSMIC	1.204	Down-regulation
AGC_PKC_PKCd_PRKCQ_ST	O14974	PPP1R12A	Q04759	PRKCQ	S692	R694T	694	Missense	proximal	2	no	1.489	1.227	EPSD	TCGA;COSMIC	1.204	Down-regulation
AGC_PKC_PKCd_PRKCQ_ST	O14974	PPP1R12A	Q04759	PRKCQ	S695	R694T	694	Missense	proximal	-1	no	1.491	1.478	EPSD	TCGA;COSMIC	1.204	Down-regulation
AGC_PKC_PKCd_PRKCQ_ST	O14974	PPP1R12A	Q04759	PRKCQ	S695	T700S	700	Missense	distal	5	no	1.491	1.496	EPSD	TCGA;ICGC;COSMIC	1.204	Up-regulation
AGC_PKC_PKCd_PRKCQ_ST	O14974	PPP1R12A	Q04759	PRKCQ	T696	R694T	694	Missense	proximal	-2	no	1.373	0.687	EPSD	TCGA;COSMIC	1.204	Loss
AGC_PKC_PKCd_PRKCQ_ST	O14974	PPP1R12A	Q04759	PRKCQ	T696	T700S	700	Missense	distal	4	no	1.373	1.398	EPSD	TCGA;ICGC;COSMIC	1.204	Up-regulation
AGC_PKC_PKCd_PRKCQ_ST	O14974	PPP1R12A	Q04759	PRKCQ	S716	R715C	715	Missense	proximal	-1	no	2.440	2.428	EPSD	TCGA;ICGC;COSMIC	1.204	Down-regulation
AGC_PKC_PKCd_PRKCQ_ST	O14974	PPP1R12A	Q04759	PRKCQ	S802	T807P	807	Missense	distal	5	no	2.142	2.150	EPSD	TCGA;ICGC;COSMIC	1.204	Up-regulation
AGC_PKC_PKCd_PRKCQ_ST	O14974	PPP1R12A	Q04759	PRKCQ	S802	T807I	807	Missense	distal	5	no	2.142	2.143	EPSD	TCGA;ICGC;COSMIC	1.204	Up-regulation
AGC_PKC_PKCd_PRKCQ_ST	O14974	PPP1R12A	Q04759	PRKCQ	S852	R851K	851	Missense	proximal	-1	no	2.201	2.196	EPSD	TCGA;ICGC;COSMIC	1.204	Down-regulation
AGC_PKC_PKCd_PRKCQ_ST	O14974	PPP1R12A	Q04759	PRKCQ	S852	T853A	853	Missense	proximal	1	no	2.201	2.205	EPSD	TCGA;ICGC;COSMIC	1.204	Up-regulation
AGC_PKC_PKCd_PRKCQ_ST	O14974	PPP1R12A	Q04759	PRKCQ	S852	S852Y	852	Missense	central	0	yes	2.201	0.000	EPSD	TCGA;ICGC	1.204	Loss
AGC_PKC_PKCd_PRKCQ_ST	O14974	PPP1R12A	Q04759	PRKCQ	T853	R851K	851	Missense	proximal	-2	no	1.351	1.107	PhosphoSitePlus	TCGA;ICGC;COSMIC	1.204	Loss
AGC_PKC_PKCd_PRKCQ_ST	O14974	PPP1R12A	Q04759	PRKCQ	T853	T853A	853	Missense	central	0	yes	1.351	0.000	PhosphoSitePlus	TCGA;ICGC;COSMIC	1.204	Loss
AGC_PKC_PKCd_PRKCQ_ST	O14974	PPP1R12A	Q04759	PRKCQ	T853	S852Y	852	Missense	proximal	-1	no	1.351	1.347	PhosphoSitePlus	TCGA;ICGC	1.204	Down-regulation
AGC_PKC_PKCd_PRKCQ_ST	O14974	PPP1R12A	Q04759	PRKCQ	S894	E891K	891	Missense	distal	-3	no	0.602	1.619	EPSD	TCGA;ICGC;COSMIC	1.204	Gain
AGC_PKC_PKCd_PRKCQ_ST	O14974	PPP1R12A	Q04759	PRKCQ	S903	S903A	903	Missense	central	0	yes	1.716	0.000	EPSD	TCGA;ICGC;COSMIC	1.204	Loss
AGC_PKC_PKCd_PRKCQ_ST	O14974	PPP1R12A	Q04759	PRKCQ	S903	R907C	907	Missense	distal	4	no	1.716	1.540	EPSD	TCGA;ICGC;COSMIC	1.204	Down-regulation
AGC_PKC_PKCd_PRKCQ_ST	O14974	PPP1R12A	Q04759	PRKCQ	S910	R907C	907	Missense	distal	-3	no	1.794	0.495	EPSD	TCGA;ICGC;COSMIC	1.204	Loss
AGC_PKC_PKCd_PRKCQ_ST	O14974	PPP1R12A	Q04759	PRKCQ	S921	P919S	919	Missense	proximal	-2	no	1.657	1.584	EPSD	TCGA	1.204	Down-regulation
AGC_PKC_PKCd_PRKCQ_ST	O14974	PPP1R12A	Q04759	PRKCQ	S922	S929L	929	Missense	distal	7	no	1.269	1.290	EPSD	TCGA;ICGC;COSMIC	1.204	Up-regulation
AGC_PKC_PKCd_PRKCQ_ST	O14974	PPP1R12A	Q04759	PRKCQ	S922	P919S	919	Missense	distal	-3	no	1.269	1.165	EPSD	TCGA	1.204	Loss
AGC_PKC_PKCd_PRKCQ_ST	O14974	PPP1R12A	Q04759	PRKCQ	S929	S929L	929	Missense	central	0	yes	1.417	0.000	EPSD	TCGA;ICGC;COSMIC	1.204	Loss
AGC_PKC_PKCd_PRKCQ_ST	O14974	PPP1R12A	Q04759	PRKCQ	S929	K933R	933	Missense	distal	4	no	1.417	1.480	EPSD	TCGA;ICGC;COSMIC	1.204	Up-regulation
AGC_PKC_PKCd_PRKCQ_ST	Q15052	ARHGEF6	Q04759	PRKCQ	S101	V94I	94	Missense	distal	-7	no	1.420	1.417	EPSD	TCGA;ICGC;COSMIC	1.204	Down-regulation
AGC_PKC_PKCd_PRKCQ_ST	Q15052	ARHGEF6	Q04759	PRKCQ	S101	K98N	98	Missense	distal	-3	no	1.420	0.657	EPSD	TCGA;COSMIC	1.204	Loss
AGC_PKC_PKCd_PRKCQ_ST	Q15052	ARHGEF6	Q04759	PRKCQ	S101	T102N	102	Missense	proximal	1	no	1.420	1.422	EPSD	TCGA;ICGC	1.204	Up-regulation
AGC_PKC_PKCd_PRKCQ_ST	Q15052	ARHGEF6	Q04759	PRKCQ	S124	S131T	131	Missense	distal	7	no	1.795	1.817	EPSD	TCGA;ICGC;COSMIC	1.204	Up-regulation
AGC_PKC_PKCd_PRKCQ_ST	Q15052	ARHGEF6	Q04759	PRKCQ	S124	N129T	129	Missense	distal	5	no	1.795	1.792	EPSD	TCGA	1.204	Down-regulation
AGC_PKC_PKCd_PRKCQ_ST	Q15052	ARHGEF6	Q04759	PRKCQ	S150	T156M	156	Missense	distal	6	no	1.234	1.253	EPSD	TCGA;COSMIC	1.204	Up-regulation
AGC_PKC_PKCd_PRKCQ_ST	Q15052	ARHGEF6	Q04759	PRKCQ	S150	K151N	151	Missense	proximal	1	no	1.234	1.227	EPSD	TCGA;ICGC;COSMIC	1.204	Down-regulation
AGC_PKC_PKCd_PRKCQ_ST	Q15052	ARHGEF6	Q04759	PRKCQ	S150	L146R	146	Missense	distal	-4	no	1.234	1.296	EPSD	TCGA;ICGC	1.204	Up-regulation
AGC_PKC_PKCd_PRKCQ_ST	Q15052	ARHGEF6	Q04759	PRKCQ	S220	R215C	215	Missense	distal	-5	no	1.562	1.301	EPSD	TCGA;COSMIC	1.204	Down-regulation
AGC_PKC_PKCd_PRKCQ_ST	Q15052	ARHGEF6	Q04759	PRKCQ	S220	R215H	215	Missense	distal	-5	no	1.562	1.341	EPSD	TCGA;COSMIC	1.204	Down-regulation
AGC_PKC_PKCd_PRKCQ_ST	Q15052	ARHGEF6	Q04759	PRKCQ	S220	R222K	222	Missense	proximal	2	no	1.562	1.480	EPSD	TCGA;COSMIC	1.204	Down-regulation
AGC_PKC_PKCd_PRKCQ_ST	Q15052	ARHGEF6	Q04759	PRKCQ	S220	L224I	224	Missense	distal	4	no	1.562	1.569	EPSD	TCGA;COSMIC	1.204	Up-regulation
AGC_PKC_PKCd_PRKCQ_ST	Q15052	ARHGEF6	Q04759	PRKCQ	S225	V229A	229	Missense	distal	4	no	2.148	2.195	PhosphoSitePlus;EPSD	TCGA;COSMIC	1.204	Up-regulation
AGC_PKC_PKCd_PRKCQ_ST	Q15052	ARHGEF6	Q04759	PRKCQ	S225	R222K	222	Missense	distal	-3	no	2.148	1.730	PhosphoSitePlus;EPSD	TCGA;COSMIC	1.204	Down-regulation
AGC_PKC_PKCd_PRKCQ_ST	Q15052	ARHGEF6	Q04759	PRKCQ	S488	P485L	485	Missense	distal	-3	no	1.525	1.161	EPSD;PhosphoSitePlus	TCGA;COSMIC	1.204	Loss
AGC_PKC_PKCd_PRKCQ_ST	Q15052	ARHGEF6	Q04759	PRKCQ	S488	R486W	486	Missense	proximal	-2	no	1.525	0.811	EPSD;PhosphoSitePlus	TCGA;COSMIC	1.204	Loss
AGC_PKC_PKCd_PRKCQ_ST	Q15052	ARHGEF6	Q04759	PRKCQ	S560	A566V	566	Missense	distal	6	no	1.452	1.432	EPSD	TCGA;COSMIC	1.204	Down-regulation
AGC_PKC_PKCd_PRKCQ_ST	Q15052	ARHGEF6	Q04759	PRKCQ	S560	S563L	563	Missense	distal	3	no	1.452	1.442	EPSD	TCGA;COSMIC	1.204	Down-regulation
AGC_PKC_PKCd_PRKCQ_ST	Q15052	ARHGEF6	Q04759	PRKCQ	S561	A566V	566	Missense	distal	5	no	1.365	1.355	EPSD	TCGA;COSMIC	1.204	Down-regulation
AGC_PKC_PKCd_PRKCQ_ST	Q15052	ARHGEF6	Q04759	PRKCQ	S561	S568F	568	Missense	distal	7	no	1.365	1.374	EPSD	TCGA;COSMIC	1.204	Up-regulation
AGC_PKC_PKCd_PRKCQ_ST	Q15052	ARHGEF6	Q04759	PRKCQ	S561	S563L	563	Missense	proximal	2	no	1.365	1.343	EPSD	TCGA;COSMIC	1.204	Down-regulation
AGC_PKC_PKCd_PRKCQ_ST	Q15052	ARHGEF6	Q04759	PRKCQ	S620	K627R	627	Missense	distal	7	no	1.272	1.214	EPSD	TCGA;COSMIC	1.204	Down-regulation
AGC_PKC_PKCd_PRKCQ_ST	Q15052	ARHGEF6	Q04759	PRKCQ	T635	K628T	628	Missense	distal	-7	no	1.566	1.580	EPSD	TCGA;COSMIC	1.204	Up-regulation
AGC_PKC_PKCd_PRKCQ_ST	Q15052	ARHGEF6	Q04759	PRKCQ	T635	L630I	630	Missense	distal	-5	no	1.566	1.575	EPSD	TCGA;COSMIC;GDSC;CCLE	1.204	Up-regulation
AGC_PKC_PKCd_PRKCQ_ST	Q15052	ARHGEF6	Q04759	PRKCQ	S640	E643Q	643	Missense	distal	3	no	1.823	1.827	EPSD	TCGA;COSMIC	1.204	Up-regulation
AGC_PKC_PKCd_PRKCQ_ST	Q15052	ARHGEF6	Q04759	PRKCQ	S649	E643Q	643	Missense	distal	-6	no	1.243	1.193	EPSD	TCGA;COSMIC	1.204	Loss
AGC_PKC_PKCd_PRKCQ_ST	Q15052	ARHGEF6	Q04759	PRKCQ	S684	Q687H	687	Missense	distal	3	no	2.236	2.235	EPSD	TCGA;COSMIC	1.204	Down-regulation
AGC_PKC_PKCd_PRKCQ_ST	Q15052	ARHGEF6	Q04759	PRKCQ	S684	D683Y	683	Missense	proximal	-1	no	2.236	2.237	EPSD	TCGA;COSMIC	1.204	Up-regulation
AGC_PKC_PKCd_PRKCQ_ST	Q15052	ARHGEF6	Q04759	PRKCQ	S684	P691H	691	Missense	distal	7	no	2.236	2.245	EPSD	TCGA	1.204	Up-regulation
AGC_PKC_PKCd_PRKCQ_ST	Q15052	ARHGEF6	Q04759	PRKCQ	S684	R681Q	681	Missense	distal	-3	no	2.236	1.008	EPSD	TCGA;COSMIC	1.204	Loss
AGC_PKC_PKCd_PRKCQ_ST	Q8IV61	RASGRP3	Q04759	PRKCQ	T133	R131I	131	Missense	proximal	-2	no	2.341	1.608	PhosphoSitePlus	TCGA;ICGC	1.204	Down-regulation
AGC_PKC_PKCd_PRKCQ_ST	Q8IV61	RASGRP3	Q04759	PRKCQ	T133	R135K	135	Missense	proximal	2	no	2.341	2.259	PhosphoSitePlus	TCGA;ICGC;COSMIC	1.204	Down-regulation
AGC_PKC_PKCd_PRKCQ_ST	Q8IV61	RASGRP3	Q04759	PRKCQ	T133	R131K	131	Missense	proximal	-2	no	2.341	2.097	PhosphoSitePlus	TCGA;ICGC;COSMIC	1.204	Down-regulation
AGC_PKC_PKCd_PRKCQ_ST	Q8IV61	RASGRP3	Q04759	PRKCQ	T133	D127N	127	Missense	distal	-6	no	2.341	2.304	PhosphoSitePlus	TCGA;ICGC;COSMIC	1.204	Down-regulation
AGC_PKC_PKCd_PRKCQ_ST	Q8IV61	RASGRP3	Q04759	PRKCQ	T133	Q134H	134	Missense	proximal	1	no	2.341	2.340	PhosphoSitePlus	TCGA;ICGC;COSMIC	1.204	Down-regulation
AGC_PKC_PKCd_PRKCQ_ST	Q8IV61	RASGRP3	Q04759	PRKCQ	S552	P551R	551	Missense	proximal	-1	no	1.608	1.617	EPSD	TCGA;ICGC;COSMIC	1.204	Up-regulation
AGC_PKC_PKCd_PRKCQ_ST	Q8IV61	RASGRP3	Q04759	PRKCQ	S554	P551R	551	Missense	distal	-3	no	1.069	2.055	EPSD	TCGA;ICGC;COSMIC	1.204	Gain
AGC_PKA_PRKACB_ST	Q01130	SRSF2	P22694	PRKACB	S121	S128R	128	Missense	distal	7	no	3.788	3.764	PhosphoSitePlus;EPSD	TCGA;ICGC;COSMIC	2.323	Down-regulation
AGC_PKA_PRKACB_ST	Q01130	SRSF2	P22694	PRKACB	S128	R129L	129	Missense	proximal	1	no	2.373	2.610	EPSD;PhosphoSitePlus	TCGA;COSMIC	2.323	Up-regulation
AGC_PKA_PRKACB_ST	Q01130	SRSF2	P22694	PRKACB	S128	R129G	129	Missense	proximal	1	no	2.373	2.342	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	2.323	Down-regulation
AGC_PKA_PRKACB_ST	Q01130	SRSF2	P22694	PRKACB	S128	S128R	128	Missense	central	0	yes	2.373	0.000	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	2.323	Loss
AGC_PKA_PRKACB_ST	Q01130	SRSF2	P22694	PRKACB	S130	R129L	129	Missense	proximal	-1	no	2.496	2.536	EPSD;PhosphoSitePlus	TCGA;COSMIC	2.323	Up-regulation
AGC_PKA_PRKACB_ST	Q01130	SRSF2	P22694	PRKACB	S130	S136C	136	Missense	distal	6	no	2.496	2.506	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	2.323	Up-regulation
AGC_PKA_PRKACB_ST	Q01130	SRSF2	P22694	PRKACB	S130	R129G	129	Missense	proximal	-1	no	2.496	2.522	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	2.323	Up-regulation
AGC_PKA_PRKACB_ST	Q01130	SRSF2	P22694	PRKACB	S130	S128R	128	Missense	proximal	-2	no	2.496	3.139	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	2.323	Up-regulation
AGC_PKA_PRKACB_ST	Q01130	SRSF2	P22694	PRKACB	S134	R129L	129	Missense	distal	-5	no	2.934	2.871	EPSD	TCGA;COSMIC	2.323	Down-regulation
AGC_PKA_PRKACB_ST	Q01130	SRSF2	P22694	PRKACB	S134	S136C	136	Missense	proximal	2	no	2.934	2.944	EPSD	TCGA;ICGC;COSMIC	2.323	Up-regulation
AGC_PKA_PRKACB_ST	Q01130	SRSF2	P22694	PRKACB	S134	R129G	129	Missense	distal	-5	no	2.934	3.381	EPSD	TCGA;ICGC;COSMIC	2.323	Up-regulation
AGC_PKA_PRKACB_ST	Q01130	SRSF2	P22694	PRKACB	S134	S128R	128	Missense	distal	-6	no	2.934	2.957	EPSD	TCGA;ICGC;COSMIC	2.323	Up-regulation
AGC_PKA_PRKACB_ST	Q01130	SRSF2	P22694	PRKACB	S136	R129L	129	Missense	distal	-7	no	3.388	3.182	EPSD	TCGA;COSMIC	2.323	Down-regulation
AGC_PKA_PRKACB_ST	Q01130	SRSF2	P22694	PRKACB	S136	S136C	136	Missense	central	0	yes	3.388	0.000	EPSD	TCGA;ICGC;COSMIC	2.323	Loss
AGC_PKA_PRKACB_ST	Q01130	SRSF2	P22694	PRKACB	S136	R129G	129	Missense	distal	-7	no	3.388	3.111	EPSD	TCGA;ICGC;COSMIC	2.323	Down-regulation
AGC_PKA_PRKACB_ST	Q01130	SRSF2	P22694	PRKACB	S136	S142F	142	Missense	distal	6	no	3.388	3.395	EPSD	TCGA;ICGC;COSMIC	2.323	Up-regulation
AGC_PKA_PRKACB_ST	Q01130	SRSF2	P22694	PRKACB	T153	S149P	149	Missense	distal	-4	no	2.409	2.519	EPSD	TCGA;COSMIC	2.323	Up-regulation
AGC_PKA_PRKACB_ST	Q01130	SRSF2	P22694	PRKACB	T153	S157Y	157	Missense	distal	4	no	2.409	2.411	EPSD	TCGA;ICGC	2.323	Up-regulation
AGC_PKA_PRKACB_ST	Q01130	SRSF2	P22694	PRKACB	S171	R167Q	167	Missense	distal	-4	no	2.390	2.405	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	2.323	Up-regulation
AGC_PKA_PRKACB_ST	Q01130	SRSF2	P22694	PRKACB	S171	R167L	167	Missense	distal	-4	no	2.390	2.412	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC;GDSC	2.323	Up-regulation
AGC_PKA_PRKACB_ST	Q01130	SRSF2	P22694	PRKACB	S171	R168K	168	Missense	distal	-3	no	2.390	2.367	EPSD;PhosphoSitePlus	TCGA;COSMIC	2.323	Down-regulation
AGC_PKA_PRKACB_ST	Q01130	SRSF2	P22694	PRKACB	S183	S179C	179	Missense	distal	-4	no	3.859	3.912	EPSD	TCGA;COSMIC	2.323	Up-regulation
AGC_PKA_PRKACB_ST	Q01130	SRSF2	P22694	PRKACB	S185	S179C	179	Missense	distal	-6	no	4.744	4.765	EPSD	TCGA;COSMIC	2.323	Up-regulation
AGC_PKA_PRKACB_ST	Q01130	SRSF2	P22694	PRKACB	S200	R205L	205	Missense	distal	5	no	3.925	3.927	EPSD	TCGA;COSMIC	2.323	Up-regulation
AGC_PKA_PRKACB_ST	Q01130	SRSF2	P22694	PRKACB	S200	S200F	200	Missense	central	0	yes	3.925	0.000	EPSD	TCGA;ICGC;COSMIC	2.323	Loss
CK1_CK1_CK1-G_CSNK1G1_ST	P25054	APC	Q9HCP0	CSNK1G1	S95	S92P	92	Missense	distal	-3	no	2.401	1.926	EPSD	TCGA;ICGC;COSMIC	1.928	Loss
CK1_CK1_CK1-G_CSNK1G1_ST	P25054	APC	Q9HCP0	CSNK1G1	S98	S92P	92	Missense	distal	-6	no	2.046	1.013	EPSD	TCGA;ICGC;COSMIC	1.928	Loss
CK1_CK1_CK1-G_CSNK1G1_ST	P25054	APC	Q9HCP0	CSNK1G1	S299	S299C	299	Missense	central	0	yes	1.952	0.000	EPSD	TCGA;ICGC;COSMIC	1.928	Loss
CK1_CK1_CK1-G_CSNK1G1_ST	P25054	APC	Q9HCP0	CSNK1G1	S299	R302Q	302	Missense	distal	3	no	1.952	1.892	EPSD	TCGA;ICGC;COSMIC	1.928	Loss
CK1_CK1_CK1-G_CSNK1G1_ST	P25054	APC	Q9HCP0	CSNK1G1	S299	S294F	294	Missense	distal	-5	no	1.952	2.064	EPSD	TCGA;ICGC;COSMIC	1.928	Up-regulation
CK1_CK1_CK1-G_CSNK1G1_ST	P25054	APC	Q9HCP0	CSNK1G1	S559	K561N	561	Missense	proximal	2	no	2.048	2.024	EPSD	TCGA;ICGC;COSMIC	1.928	Down-regulation
CK1_CK1_CK1-G_CSNK1G1_ST	P25054	APC	Q9HCP0	CSNK1G1	S559	T562M	562	Missense	distal	3	no	2.048	2.049	EPSD	TCGA;ICGC;COSMIC	1.928	Up-regulation
CK1_CK1_CK1-G_CSNK1G1_ST	P25054	APC	Q9HCP0	CSNK1G1	S751	P745H	745	Missense	distal	-6	no	1.836	2.072	EPSD	TCGA;ICGC;COSMIC	1.928	Gain
CK1_CK1_CK1-G_CSNK1G1_ST	P25054	APC	Q9HCP0	CSNK1G1	S780	D777G	777	Missense	distal	-3	no	2.279	2.122	EPSD	TCGA;ICGC;COSMIC	1.928	Down-regulation
CK1_CK1_CK1-G_CSNK1G1_ST	P25054	APC	Q9HCP0	CSNK1G1	S780	R786H	786	Missense	distal	6	no	2.279	2.302	EPSD	TCGA;ICGC;COSMIC	1.928	Up-regulation
CK1_CK1_CK1-G_CSNK1G1_ST	P25054	APC	Q9HCP0	CSNK1G1	S780	N778S	778	Missense	proximal	-2	no	2.279	2.314	EPSD	TCGA;ICGC;COSMIC	1.928	Up-regulation
CK1_CK1_CK1-G_CSNK1G1_ST	P25054	APC	Q9HCP0	CSNK1G1	T867	P865S	865	Missense	proximal	-2	no	1.988	2.054	EPSD	TCGA;ICGC;COSMIC	1.928	Up-regulation
CK1_CK1_CK1-G_CSNK1G1_ST	P25054	APC	Q9HCP0	CSNK1G1	T867	E868Q	868	Missense	proximal	1	no	1.988	1.986	EPSD	TCGA;ICGC;COSMIC	1.928	Down-regulation
CK1_CK1_CK1-G_CSNK1G1_ST	P25054	APC	Q9HCP0	CSNK1G1	T867	E868D	868	Missense	proximal	1	no	1.988	1.913	EPSD	TCGA;ICGC;COSMIC	1.928	Loss
CK1_CK1_CK1-G_CSNK1G1_ST	P25054	APC	Q9HCP0	CSNK1G1	S874	E868Q	868	Missense	distal	-6	no	2.555	2.381	EPSD	TCGA;ICGC;COSMIC	1.928	Down-regulation
CK1_CK1_CK1-G_CSNK1G1_ST	P25054	APC	Q9HCP0	CSNK1G1	S874	E868D	868	Missense	distal	-6	no	2.555	3.087	EPSD	TCGA;ICGC;COSMIC	1.928	Up-regulation
CK1_CK1_CK1-G_CSNK1G1_ST	P25054	APC	Q9HCP0	CSNK1G1	S963	S959Y	959	Missense	distal	-4	no	3.170	3.148	EPSD	TCGA;ICGC;COSMIC	1.928	Down-regulation
CK1_CK1_CK1-G_CSNK1G1_ST	P25054	APC	Q9HCP0	CSNK1G1	S963	S966G	966	Missense	distal	3	no	3.170	3.118	EPSD	TCGA;ICGC;COSMIC	1.928	Down-regulation
CK1_CK1_CK1-G_CSNK1G1_ST	P25054	APC	Q9HCP0	CSNK1G1	S1128	N1122D	1122	Missense	distal	-6	no	1.539	1.949	EPSD	TCGA;ICGC;COSMIC	1.928	Gain
CK1_CK1_CK1-G_CSNK1G1_ST	P25054	APC	Q9HCP0	CSNK1G1	S1371	Q1367E	1367	Missense	distal	-4	no	1.970	1.977	EPSD	TCGA;ICGC;COSMIC	1.928	Up-regulation
CK1_CK1_CK1-G_CSNK1G1_ST	P25054	APC	Q9HCP0	CSNK1G1	S1504	A1508D	1508	Missense	distal	4	no	5.966	5.604	EPSD;PhosphoSitePlus	TCGA;ICGC	1.928	Down-regulation
CK1_CK1_CK1-G_CSNK1G1_ST	P25054	APC	Q9HCP0	CSNK1G1	S1505	A1508D	1508	Missense	distal	3	no	5.317	5.457	EPSD;PhosphoSitePlus	TCGA;ICGC	1.928	Up-regulation
CK1_CK1_CK1-G_CSNK1G1_ST	P25054	APC	Q9HCP0	CSNK1G1	S1507	A1508D	1508	Missense	proximal	1	no	5.668	5.516	PhosphoSitePlus;EPSD	TCGA;ICGC	1.928	Down-regulation
CK1_CK1_CK1-G_CSNK1G1_ST	P25054	APC	Q9HCP0	CSNK1G1	S1510	A1508D	1508	Missense	proximal	-2	no	5.287	5.303	EPSD;PhosphoSitePlus	TCGA;ICGC	1.928	Up-regulation
CK1_CK1_CK1-G_CSNK1G1_ST	P25054	APC	Q9HCP0	CSNK1G1	S1539	E1540G	1540	Missense	proximal	1	no	2.392	2.412	EPSD	TCGA;ICGC;COSMIC	1.928	Up-regulation
CK1_CK1_CK1-G_CSNK1G1_ST	P25054	APC	Q9HCP0	CSNK1G1	S1539	S1539L	1539	Missense	central	0	yes	2.392	0.000	EPSD	TCGA;ICGC;COSMIC	1.928	Loss
CK1_CK1_CK1-G_CSNK1G1_ST	P25054	APC	Q9HCP0	CSNK1G1	S1652	D1659V	1659	Missense	distal	7	no	2.224	2.234	EPSD	TCGA;ICGC;COSMIC	1.928	Up-regulation
CK1_CK1_CK1-G_CSNK1G1_ST	P25054	APC	Q9HCP0	CSNK1G1	T1653	D1659V	1659	Missense	distal	6	no	1.825	1.935	EPSD	TCGA;ICGC;COSMIC	1.928	Gain
CK1_CK1_CK1-G_CSNK1G1_ST	P25054	APC	Q9HCP0	CSNK1G1	T1655	D1659V	1659	Missense	distal	4	no	2.326	2.655	EPSD	TCGA;ICGC;COSMIC	1.928	Up-regulation
CK1_CK1_CK1-G_CSNK1G1_ST	P25054	APC	Q9HCP0	CSNK1G1	S1658	D1659V	1659	Missense	proximal	1	no	2.003	2.262	EPSD	TCGA;ICGC;COSMIC	1.928	Up-regulation
CK1_CK1_CK1-G_CSNK1G1_ST	P25054	APC	Q9HCP0	CSNK1G1	T1661	D1659V	1659	Missense	proximal	-2	no	2.545	2.547	EPSD	TCGA;ICGC;COSMIC	1.928	Up-regulation
CK1_CK1_CK1-G_CSNK1G1_ST	P25054	APC	Q9HCP0	CSNK1G1	S1861	S1861Y	1861	Missense	central	0	yes	1.959	0.000	EPSD	TCGA;ICGC;COSMIC	1.928	Loss
CK1_CK1_CK1-G_CSNK1G1_ST	P25054	APC	Q9HCP0	CSNK1G1	S1863	S1861Y	1861	Missense	proximal	-2	no	2.538	2.512	EPSD	TCGA;ICGC;COSMIC	1.928	Down-regulation
CK1_CK1_CK1-G_CSNK1G1_ST	P25054	APC	Q9HCP0	CSNK1G1	S2034	S2029Y	2029	Missense	distal	-5	no	2.197	2.298	EPSD	TCGA;ICGC;COSMIC	1.928	Up-regulation
CK1_CK1_CK1-G_CSNK1G1_ST	P25054	APC	Q9HCP0	CSNK1G1	S2034	S2029F	2029	Missense	distal	-5	no	2.197	2.310	EPSD	TCGA;ICGC;COSMIC	1.928	Up-regulation
CK1_CK1_CK1-G_CSNK1G1_ST	P25054	APC	Q9HCP0	CSNK1G1	S2349	P2346S	2346	Missense	distal	-3	no	1.975	2.449	EPSD	TCGA;ICGC;COSMIC	1.928	Up-regulation
CK1_CK1_CK1-G_CSNK1G1_ST	P25054	APC	Q9HCP0	CSNK1G1	S2359	G2360S	2360	Missense	proximal	1	no	2.784	2.837	EPSD	TCGA;ICGC;COSMIC	1.928	Up-regulation
CK1_CK1_CK1-G_CSNK1G1_ST	P25054	APC	Q9HCP0	CSNK1G1	S2374	Q2372H	2372	Missense	proximal	-2	no	2.089	2.097	EPSD	TCGA;ICGC;COSMIC	1.928	Up-regulation
CK1_CK1_CK1-G_CSNK1G1_ST	P25054	APC	Q9HCP0	CSNK1G1	S2396	Q2403H	2403	Missense	distal	7	no	2.015	2.014	EPSD	TCGA;ICGC;COSMIC	1.928	Down-regulation
CK1_CK1_CK1-G_CSNK1G1_ST	P25054	APC	Q9HCP0	CSNK1G1	S2396	L2401P	2401	Missense	distal	5	no	2.015	2.010	EPSD	TCGA;ICGC;COSMIC	1.928	Down-regulation
CK1_CK1_CK1-G_CSNK1G1_ST	P25054	APC	Q9HCP0	CSNK1G1	S2427	S2429F	2429	Missense	proximal	2	no	2.689	2.850	EPSD	TCGA;COSMIC	1.928	Up-regulation
CK1_CK1_CK1-G_CSNK1G1_ST	P25054	APC	Q9HCP0	CSNK1G1	S2427	D2430H	2430	Missense	distal	3	no	2.689	2.574	EPSD	TCGA;ICGC;COSMIC	1.928	Down-regulation
CK1_CK1_CK1-G_CSNK1G1_ST	P25054	APC	Q9HCP0	CSNK1G1	T2475	A2472D	2472	Missense	distal	-3	no	1.646	2.093	EPSD	TCGA;ICGC	1.928	Gain
CK1_CK1_CK1-G_CSNK1G1_ST	P25054	APC	Q9HCP0	CSNK1G1	S2575	S2569N	2569	Missense	distal	-6	no	2.091	1.472	EPSD	TCGA;ICGC;COSMIC	1.928	Loss
CK1_CK1_CK1-G_CSNK1G1_ST	P25054	APC	Q9HCP0	CSNK1G1	S2575	L2574I	2574	Missense	proximal	-1	no	2.091	2.067	EPSD	TCGA;ICGC;COSMIC	1.928	Down-regulation
CK1_CK1_CK1-G_CSNK1G1_ST	P25054	APC	Q9HCP0	CSNK1G1	S2575	S2577P	2577	Missense	proximal	2	no	2.091	2.293	EPSD	TCGA;ICGC	1.928	Up-regulation
CK1_CK1_CK1-G_CSNK1G1_ST	P25054	APC	Q9HCP0	CSNK1G1	S2627	N2624D	2624	Missense	distal	-3	no	2.082	2.353	EPSD	TCGA;ICGC;COSMIC	1.928	Up-regulation
CK1_CK1_CK1-G_CSNK1G1_ST	O75581	LRP6	Q9HCP0	CSNK1G1	S646	I645L	645	Missense	proximal	-1	no	2.084	2.108	EPSD	TCGA;ICGC;COSMIC	1.928	Up-regulation
CK1_CK1_CK1-G_CSNK1G1_ST	O75581	LRP6	Q9HCP0	CSNK1G1	S646	R644Q	644	Missense	proximal	-2	no	2.084	2.057	EPSD	TCGA;ICGC;COSMIC	1.928	Down-regulation
CK1_CK1_CK1-G_CSNK1G1_ST	O75581	LRP6	Q9HCP0	CSNK1G1	S646	I642S	642	Missense	distal	-4	no	2.084	2.108	EPSD	TCGA	1.928	Up-regulation
CK1_CK1_CK1-G_CSNK1G1_ST	O75581	LRP6	Q9HCP0	CSNK1G1	T1408	E1407K	1407	Missense	proximal	-1	no	1.931	1.899	EPSD	TCGA;COSMIC	1.928	Loss
CK1_CK1_CK1-G_CSNK1G1_ST	O75581	LRP6	Q9HCP0	CSNK1G1	T1511	S1505Y	1505	Missense	distal	-6	no	3.064	2.316	EPSD	TCGA	1.928	Down-regulation
CK1_CK1_CK1-G_CSNK1G1_ST	Q04206	RELA	Q9HCP0	CSNK1G1	S311	F309L	309	Missense	proximal	-2	no	1.998	2.021	EPSD	TCGA;ICGC;COSMIC	1.928	Up-regulation
CK1_CK1_CK1-G_CSNK1G1_ST	Q04206	RELA	Q9HCP0	CSNK1G1	S311	E307K	307	Missense	distal	-4	no	1.998	1.988	EPSD	TCGA;ICGC;COSMIC	1.928	Down-regulation
CK1_CK1_CK1-G_CSNK1G1_ST	Q04206	RELA	Q9HCP0	CSNK1G1	S311	T308A	308	Missense	distal	-3	no	1.998	1.656	EPSD	TCGA;ICGC;COSMIC	1.928	Loss
CK1_CK1_CK1-G_CSNK1G1_ST	Q04206	RELA	Q9HCP0	CSNK1G1	S468	V469I	469	Missense	proximal	1	no	2.623	2.550	EPSD	TCGA;ICGC;COSMIC	1.928	Down-regulation
CK1_CK1_CK1-G_CSNK1G1_ST	Q04206	RELA	Q9HCP0	CSNK1G1	S472	V469I	469	Missense	distal	-3	no	2.443	2.267	EPSD	TCGA;ICGC;COSMIC	1.928	Down-regulation
CK1_CK1_CK1-G_CSNK1G1_ST	Q04206	RELA	Q9HCP0	CSNK1G1	S536	S529L	529	Missense	distal	-7	no	3.108	2.962	PhosphoSitePlus	TCGA;ICGC;COSMIC;GDSC;CCLE	1.928	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	P12931	SRC	O14757	CHEK1	S12	S6N	6	Missense	distal	-6	no	8.908	8.949	EPSD	TCGA;ICGC;COSMIC	5.604	Up-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	P12931	SRC	O14757	CHEK1	S12	R14W	14	Missense	proximal	2	no	8.908	8.734	EPSD	TCGA;ICGC;COSMIC	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	P12931	SRC	O14757	CHEK1	S17	R14W	14	Missense	distal	-3	no	9.633	-23.970	EPSD	TCGA;ICGC;COSMIC	5.604	Loss
CAMK_CAMKL_CHK1_CHEK1_ST	P12931	SRC	O14757	CHEK1	T101	T101A	101	Missense	central	0	yes	6.978	0.000	EPSD	TCGA;ICGC;COSMIC	5.604	Loss
CAMK_CAMKL_CHK1_CHEK1_ST	P12931	SRC	O14757	CHEK1	T101	R98M	98	Missense	distal	-3	no	6.978	1.829	EPSD	TCGA;ICGC;COSMIC	5.604	Loss
CAMK_CAMKL_CHK1_CHEK1_ST	P12931	SRC	O14757	CHEK1	T101	S104F	104	Missense	distal	3	no	6.978	7.166	EPSD	TCGA;ICGC;COSMIC	5.604	Up-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	P12931	SRC	O14757	CHEK1	T101	E96V	96	Missense	distal	-5	no	6.978	7.864	EPSD	TCGA;ICGC;COSMIC	5.604	Up-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	P12931	SRC	O14757	CHEK1	S104	T101A	101	Missense	distal	-3	no	-6.110	7.747	EPSD	TCGA;ICGC;COSMIC	5.604	Gain
CAMK_CAMKL_CHK1_CHEK1_ST	P12931	SRC	O14757	CHEK1	T443	S450F	450	Missense	distal	7	no	6.263	5.833	EPSD	TCGA;ICGC;COSMIC	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q6PD62	CTR9	O14757	CHEK1	T263	P266S	266	Missense	distal	3	no	12.864	12.535	EPSD	TCGA;ICGC	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q6PD62	CTR9	O14757	CHEK1	T263	L258I	258	Missense	distal	-5	no	12.864	10.833	EPSD	TCGA;ICGC	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q6PD62	CTR9	O14757	CHEK1	T766	D771N	771	Missense	distal	5	no	8.467	8.378	EPSD	TCGA;ICGC;COSMIC	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q6PD62	CTR9	O14757	CHEK1	S941	K935N	935	Missense	distal	-6	no	12.944	13.075	EPSD	TCGA;ICGC;COSMIC	5.604	Up-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q6PD62	CTR9	O14757	CHEK1	S1054	D1060Y	1060	Missense	distal	6	no	9.751	10.676	EPSD	TCGA;ICGC;COSMIC	5.604	Up-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q6PD62	CTR9	O14757	CHEK1	S1054	E1047K	1047	Missense	distal	-7	no	9.751	10.449	EPSD	TCGA;ICGC;COSMIC	5.604	Up-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q6PD62	CTR9	O14757	CHEK1	S1081	R1074W	1074	Missense	distal	-7	no	8.022	6.476	PhosphoSitePlus	TCGA;ICGC;COSMIC	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q6PD62	CTR9	O14757	CHEK1	S1097	S1091T	1091	Missense	distal	-6	no	9.646	9.715	EPSD	TCGA;ICGC;COSMIC	5.604	Up-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q6PD62	CTR9	O14757	CHEK1	S1114	S1112N	1112	Missense	proximal	-2	no	8.649	8.838	EPSD	TCGA;ICGC;COSMIC	5.604	Up-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	P11047	LAMC1	O14757	CHEK1	S159	R165C	165	Missense	distal	6	no	7.612	7.906	EPSD	TCGA;ICGC;COSMIC	5.604	Up-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	P11047	LAMC1	O14757	CHEK1	S159	H153Y	153	Missense	distal	-6	no	7.612	7.745	EPSD	TCGA;ICGC;COSMIC	5.604	Up-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	P11047	LAMC1	O14757	CHEK1	S159	A161G	161	Missense	proximal	2	no	7.612	7.091	EPSD	TCGA;ICGC;COSMIC	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	P11047	LAMC1	O14757	CHEK1	T258	R255H	255	Missense	distal	-3	no	13.605	7.796	PhosphoSitePlus	TCGA;ICGC;COSMIC;GDSC;CCLE	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	P11047	LAMC1	O14757	CHEK1	S578	Q575R	575	Missense	distal	-3	no	1.851	9.058	EPSD	TCGA;ICGC;COSMIC	5.604	Gain
CAMK_CAMKL_CHK1_CHEK1_ST	P11047	LAMC1	O14757	CHEK1	S1149	E1146K	1146	Missense	distal	-3	no	5.583	8.846	EPSD	TCGA;ICGC;COSMIC	5.604	Gain
CAMK_CAMKL_CHK1_CHEK1_ST	P11047	LAMC1	O14757	CHEK1	S1149	K1156N	1156	Missense	distal	7	no	5.583	5.645	EPSD	TCGA;ICGC;COSMIC	5.604	Gain
CAMK_CAMKL_CHK1_CHEK1_ST	P11047	LAMC1	O14757	CHEK1	S1149	R1143W	1143	Missense	distal	-6	no	5.583	5.903	EPSD	TCGA;ICGC;COSMIC	5.604	Gain
CAMK_CAMKL_CHK1_CHEK1_ST	P11047	LAMC1	O14757	CHEK1	S1552	D1555H	1555	Missense	distal	3	no	6.723	5.193	EPSD	TCGA;ICGC;COSMIC	5.604	Loss
CAMK_CAMKL_CHK1_CHEK1_ST	P11047	LAMC1	O14757	CHEK1	S1552	V1558M	1558	Missense	distal	6	no	6.723	6.848	EPSD	TCGA;ICGC;COSMIC	5.604	Up-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	P11047	LAMC1	O14757	CHEK1	S1559	D1555H	1555	Missense	distal	-4	no	14.923	14.663	EPSD	TCGA;ICGC;COSMIC	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	P11047	LAMC1	O14757	CHEK1	S1559	V1558M	1558	Missense	proximal	-1	no	14.923	14.879	EPSD	TCGA;ICGC;COSMIC	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q9NUU7	DDX19A	O14757	CHEK1	T34	N35S	35	Missense	proximal	1	no	7.302	7.305	EPSD	TCGA;ICGC;COSMIC	5.604	Up-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q9NUU7	DDX19A	O14757	CHEK1	T34	S41N	41	Missense	distal	7	no	7.302	7.531	EPSD	TCGA;ICGC;COSMIC	5.604	Up-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q9NUU7	DDX19A	O14757	CHEK1	T34	G36D	36	Missense	proximal	2	no	7.302	7.833	EPSD	TCGA;ICGC	5.604	Up-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q9NUU7	DDX19A	O14757	CHEK1	T42	N35S	35	Missense	distal	-7	no	5.399	5.936	EPSD	TCGA;ICGC;COSMIC	5.604	Gain
CAMK_CAMKL_CHK1_CHEK1_ST	Q9NUU7	DDX19A	O14757	CHEK1	T42	S41N	41	Missense	proximal	-1	no	5.399	5.617	EPSD	TCGA;ICGC;COSMIC	5.604	Gain
CAMK_CAMKL_CHK1_CHEK1_ST	Q9NUU7	DDX19A	O14757	CHEK1	S346	T344R	344	Missense	proximal	-2	no	7.002	6.847	EPSD	TCGA;COSMIC	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q9NUU7	DDX19A	O14757	CHEK1	S353	K354Q	354	Missense	proximal	1	no	8.920	8.929	EPSD	TCGA	5.604	Up-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q9NUU7	DDX19A	O14757	CHEK1	T467	E463G	463	Missense	distal	-4	no	11.433	11.256	EPSD	TCGA;COSMIC	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q9NUU7	DDX19A	O14757	CHEK1	T467	D468Y	468	Missense	proximal	1	no	11.433	11.310	EPSD	TCGA	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	P22626	HNRNPA2B1	O14757	CHEK1	S85	D87H	87	Missense	proximal	2	no	7.328	6.785	EPSD	TCGA;ICGC;COSMIC	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	P22626	HNRNPA2B1	O14757	CHEK1	S85	E92Q	92	Missense	distal	7	no	7.328	7.242	EPSD	TCGA;ICGC;COSMIC	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	P22626	HNRNPA2B1	O14757	CHEK1	S102	H108P	108	Missense	distal	6	no	9.122	9.365	EPSD	TCGA;ICGC;COSMIC	5.604	Up-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	P22626	HNRNPA2B1	O14757	CHEK1	S102	K104N	104	Missense	proximal	2	no	9.122	8.713	EPSD	TCGA;ICGC;COSMIC	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	P22626	HNRNPA2B1	O14757	CHEK1	S102	E101G	101	Missense	proximal	-1	no	9.122	9.229	EPSD	TCGA;ICGC;COSMIC	5.604	Up-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	P22626	HNRNPA2B1	O14757	CHEK1	S189	S189P	189	Missense	central	0	yes	8.250	0.000	EPSD	TCGA;ICGC;COSMIC	5.604	Loss
CAMK_CAMKL_CHK1_CHEK1_ST	P22626	HNRNPA2B1	O14757	CHEK1	S189	A187V	187	Missense	proximal	-2	no	8.250	8.327	EPSD	TCGA;ICGC;COSMIC	5.604	Up-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	P22626	HNRNPA2B1	O14757	CHEK1	S189	R190T	190	Missense	proximal	1	no	8.250	8.232	EPSD	TCGA;ICGC;COSMIC	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	P22626	HNRNPA2B1	O14757	CHEK1	S189	E192K	192	Missense	distal	3	no	8.250	7.434	EPSD	TCGA;ICGC;COSMIC	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	P22626	HNRNPA2B1	O14757	CHEK1	S231	R238S	238	Missense	distal	7	no	7.700	7.608	EPSD	TCGA;ICGC;COSMIC	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	P22626	HNRNPA2B1	O14757	CHEK1	S231	G233A	233	Missense	proximal	2	no	7.700	8.221	EPSD	TCGA;ICGC;COSMIC	5.604	Up-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	P22626	HNRNPA2B1	O14757	CHEK1	S231	G237V	237	Missense	distal	6	no	7.700	7.764	EPSD	TCGA;ICGC;COSMIC	5.604	Up-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	P22626	HNRNPA2B1	O14757	CHEK1	S231	R238C	238	Missense	distal	7	no	7.700	7.295	EPSD	TCGA;ICGC;COSMIC;GDSC;CCLE	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	P84098	RPL19	O14757	CHEK1	S12	K8N	8	Missense	distal	-4	no	11.238	11.123	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	P84098	RPL19	O14757	CHEK1	S12	R16C	16	Missense	distal	4	no	11.238	11.342	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	5.604	Up-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	P84098	RPL19	O14757	CHEK1	T29	E28K	28	Missense	proximal	-1	no	6.088	6.030	EPSD	TCGA;COSMIC	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	P84098	RPL19	O14757	CHEK1	T29	D25H	25	Missense	distal	-4	no	6.088	5.828	EPSD	TCGA;ICGC;COSMIC	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	P84098	RPL19	O14757	CHEK1	T29	E31K	31	Missense	proximal	2	no	6.088	6.129	EPSD	TCGA;COSMIC	5.604	Up-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	P84098	RPL19	O14757	CHEK1	T29	L24V	24	Missense	distal	-5	no	6.088	2.611	EPSD	TCGA;COSMIC	5.604	Loss
CAMK_CAMKL_CHK1_CHEK1_ST	P84098	RPL19	O14757	CHEK1	T56	R62G	62	Missense	distal	6	no	5.624	5.748	PhosphoSitePlus;EPSD	TCGA;COSMIC	5.604	Up-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	P84098	RPL19	O14757	CHEK1	T56	R52C	52	Missense	distal	-4	no	5.624	5.250	PhosphoSitePlus;EPSD	TCGA;COSMIC	5.604	Loss
CAMK_CAMKL_CHK1_CHEK1_ST	P84098	RPL19	O14757	CHEK1	T67	R62G	62	Missense	distal	-5	no	10.349	10.183	EPSD	TCGA;COSMIC	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	P84098	RPL19	O14757	CHEK1	T67	T67I	67	Missense	central	0	yes	10.349	0.000	EPSD	TCGA;ICGC;COSMIC	5.604	Loss
CAMK_CAMKL_CHK1_CHEK1_ST	P84098	RPL19	O14757	CHEK1	S189	E193K	193	Missense	distal	4	no	6.586	6.580	EPSD	TCGA;ICGC;COSMIC	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	P84098	RPL19	O14757	CHEK1	S189	E191K	191	Missense	proximal	2	no	6.586	6.628	EPSD	TCGA;ICGC;COSMIC	5.604	Up-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	P67809	YBX1	O14757	CHEK1	T303	Q298L	298	Missense	distal	-5	no	2.878	6.251	EPSD	TCGA	5.604	Gain
CAMK_CAMKL_CHK1_CHEK1_ST	P67809	YBX1	O14757	CHEK1	S314	P309L	309	Missense	distal	-5	no	1.699	6.405	EPSD	TCGA;ICGC;COSMIC	5.604	Gain
CAMK_CAMKL_CHK1_CHEK1_ST	Q7Z2Z1	TICRR	O14757	CHEK1	S613	T616A	616	Missense	distal	3	no	6.310	6.548	EPSD	TCGA;ICGC;COSMIC	5.604	Up-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q7Z2Z1	TICRR	O14757	CHEK1	T626	S630Y	630	Missense	distal	4	no	8.697	8.871	EPSD	TCGA;ICGC	5.604	Up-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q7Z2Z1	TICRR	O14757	CHEK1	S836	R832G	832	Missense	distal	-4	no	7.648	7.674	EPSD	TCGA;ICGC;COSMIC	5.604	Up-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q7Z2Z1	TICRR	O14757	CHEK1	S836	D842N	842	Missense	distal	6	no	7.648	7.966	EPSD	TCGA;ICGC;COSMIC	5.604	Up-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q7Z2Z1	TICRR	O14757	CHEK1	S836	S830G	830	Missense	distal	-6	no	7.648	7.686	EPSD	TCGA;ICGC;COSMIC	5.604	Up-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q7Z2Z1	TICRR	O14757	CHEK1	S851	N858T	858	Missense	distal	7	no	7.281	6.985	EPSD	TCGA;ICGC;COSMIC	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q7Z2Z1	TICRR	O14757	CHEK1	S851	R848G	848	Missense	distal	-3	no	7.281	-0.493	EPSD	TCGA	5.604	Loss
CAMK_CAMKL_CHK1_CHEK1_ST	Q7Z2Z1	TICRR	O14757	CHEK1	S851	R848C	848	Missense	distal	-3	no	7.281	-0.810	EPSD	TCGA;ICGC;COSMIC	5.604	Loss
CAMK_CAMKL_CHK1_CHEK1_ST	Q7Z2Z1	TICRR	O14757	CHEK1	S865	N858T	858	Missense	distal	-7	no	12.767	12.438	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q7Z2Z1	TICRR	O14757	CHEK1	S865	A867V	867	Missense	proximal	2	no	12.767	12.204	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q7Z2Z1	TICRR	O14757	CHEK1	S865	E868D	868	Missense	distal	3	no	12.767	12.865	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	5.604	Up-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q7Z2Z1	TICRR	O14757	CHEK1	S891	R884T	884	Missense	distal	-7	no	7.297	6.690	EPSD	TCGA;ICGC;COSMIC	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q7Z2Z1	TICRR	O14757	CHEK1	S891	E889Q	889	Missense	proximal	-2	no	7.297	7.382	EPSD	TCGA;ICGC;COSMIC	5.604	Up-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q7Z2Z1	TICRR	O14757	CHEK1	S891	A885V	885	Missense	distal	-6	no	7.297	7.435	EPSD	TCGA;ICGC	5.604	Up-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q7Z2Z1	TICRR	O14757	CHEK1	S938	R931Q	931	Missense	distal	-7	no	11.595	11.853	EPSD	TCGA;ICGC;COSMIC;GDSC;CCLE	5.604	Up-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q7Z2Z1	TICRR	O14757	CHEK1	S1026	S1031C	1031	Missense	distal	5	no	8.434	8.087	EPSD	TCGA;ICGC;COSMIC	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q7Z2Z1	TICRR	O14757	CHEK1	S1026	A1027V	1027	Missense	proximal	1	no	8.434	8.410	EPSD	TCGA;ICGC;COSMIC	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q7Z2Z1	TICRR	O14757	CHEK1	S1026	S1033P	1033	Missense	distal	7	no	8.434	8.489	EPSD	TCGA;ICGC	5.604	Up-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q7Z2Z1	TICRR	O14757	CHEK1	S1045	R1038Q	1038	Missense	distal	-7	no	9.058	9.316	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	5.604	Up-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q7Z2Z1	TICRR	O14757	CHEK1	S1045	D1052E	1052	Missense	distal	7	no	9.058	9.000	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q7Z2Z1	TICRR	O14757	CHEK1	S1057	R1054K	1054	Missense	distal	-3	no	9.076	5.250	EPSD	TCGA;ICGC;COSMIC	5.604	Loss
CAMK_CAMKL_CHK1_CHEK1_ST	Q7Z2Z1	TICRR	O14757	CHEK1	S1057	D1052E	1052	Missense	distal	-5	no	9.076	8.676	EPSD	TCGA;ICGC;COSMIC	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q7Z2Z1	TICRR	O14757	CHEK1	S1057	R1063W	1063	Missense	distal	6	no	9.076	9.542	EPSD	TCGA;ICGC;COSMIC	5.604	Up-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q7Z2Z1	TICRR	O14757	CHEK1	S1125	I1124M	1124	Missense	proximal	-1	no	9.804	9.898	EPSD	TCGA;ICGC;COSMIC	5.604	Up-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q7Z2Z1	TICRR	O14757	CHEK1	S1125	S1125C	1125	Missense	central	0	yes	9.804	0.000	EPSD	TCGA;ICGC;COSMIC	5.604	Loss
CAMK_CAMKL_CHK1_CHEK1_ST	Q7Z2Z1	TICRR	O14757	CHEK1	S1125	P1121A	1121	Missense	distal	-4	no	9.804	9.948	EPSD	TCGA;ICGC;COSMIC;GDSC;CCLE	5.604	Up-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q7Z2Z1	TICRR	O14757	CHEK1	S1161	S1167L	1167	Missense	distal	6	no	6.137	6.547	EPSD	TCGA;ICGC;COSMIC	5.604	Up-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q7Z2Z1	TICRR	O14757	CHEK1	S1161	L1157F	1157	Missense	distal	-4	no	6.137	5.843	EPSD	TCGA;ICGC;COSMIC	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q7Z2Z1	TICRR	O14757	CHEK1	S1224	S1224C	1224	Missense	central	0	yes	6.096	0.000	EPSD	TCGA;ICGC;COSMIC	5.604	Loss
CAMK_CAMKL_CHK1_CHEK1_ST	Q7Z2Z1	TICRR	O14757	CHEK1	S1394	Q1399P	1399	Missense	distal	5	no	6.766	6.712	EPSD	TCGA;ICGC;COSMIC	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q7Z2Z1	TICRR	O14757	CHEK1	S1428	G1426R	1426	Missense	proximal	-2	no	6.687	6.653	EPSD	TCGA;ICGC;COSMIC	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q7Z2Z1	TICRR	O14757	CHEK1	S1428	P1435L	1435	Missense	distal	7	no	6.687	6.623	EPSD	TCGA;ICGC;COSMIC	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q7Z2Z1	TICRR	O14757	CHEK1	S1428	Q1424R	1424	Missense	distal	-4	no	6.687	6.527	EPSD	TCGA;ICGC;COSMIC	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q7Z2Z1	TICRR	O14757	CHEK1	S1615	P1608H	1608	Missense	distal	-7	no	5.556	5.907	EPSD	TCGA;ICGC;COSMIC;GDSC;CCLE	5.604	Gain
CAMK_CAMKL_CHK1_CHEK1_ST	Q7Z2Z1	TICRR	O14757	CHEK1	S1772	G1769R	1769	Missense	distal	-3	no	-0.448	7.327	EPSD	TCGA;ICGC;COSMIC	5.604	Gain
CAMK_CAMKL_CHK1_CHEK1_ST	Q7Z2Z1	TICRR	O14757	CHEK1	S1797	D1796E	1796	Missense	proximal	-1	no	5.667	5.608	EPSD	TCGA;ICGC;COSMIC	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q7Z2Z1	TICRR	O14757	CHEK1	S1797	C1791R	1791	Missense	distal	-6	no	5.667	5.552	EPSD	TCGA;ICGC	5.604	Loss
CAMK_CAMKL_CHK1_CHEK1_ST	Q7Z2Z1	TICRR	O14757	CHEK1	S1894	T1896A	1896	Missense	proximal	2	no	7.027	7.875	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	5.604	Up-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q7Z2Z1	TICRR	O14757	CHEK1	S1894	T1896I	1896	Missense	proximal	2	no	7.027	6.913	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q7Z2Z1	TICRR	O14757	CHEK1	S1894	S1888F	1888	Missense	distal	-6	no	7.027	7.301	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	5.604	Up-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q7Z2Z1	TICRR	O14757	CHEK1	S1894	R1891C	1891	Missense	distal	-3	no	7.027	-1.064	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	5.604	Loss
CAMK_CAMKL_CHK1_CHEK1_ST	Q7Z2Z1	TICRR	O14757	CHEK1	S1894	P1892L	1892	Missense	proximal	-2	no	7.027	6.848	EPSD;PhosphoSitePlus	TCGA;ICGC	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q7Z2Z1	TICRR	O14757	CHEK1	T1898	T1896A	1896	Missense	proximal	-2	no	9.472	9.332	PhosphoSitePlus;EPSD	TCGA;ICGC;COSMIC	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q7Z2Z1	TICRR	O14757	CHEK1	T1898	T1896I	1896	Missense	proximal	-2	no	9.472	9.346	PhosphoSitePlus;EPSD	TCGA;ICGC;COSMIC	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q7Z2Z1	TICRR	O14757	CHEK1	T1898	R1891C	1891	Missense	distal	-7	no	9.472	8.744	PhosphoSitePlus;EPSD	TCGA;ICGC;COSMIC	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q7Z2Z1	TICRR	O14757	CHEK1	T1898	P1892L	1892	Missense	distal	-6	no	9.472	9.399	PhosphoSitePlus;EPSD	TCGA;ICGC	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q9NRL2	BAZ1A	O14757	CHEK1	S601	P594L	594	Missense	distal	-7	no	7.837	7.623	EPSD	TCGA;ICGC;COSMIC	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q9NRL2	BAZ1A	O14757	CHEK1	S842	Q849R	849	Missense	distal	7	no	7.148	6.993	EPSD	TCGA;ICGC;COSMIC	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q9NRL2	BAZ1A	O14757	CHEK1	S960	R959T	959	Missense	proximal	-1	no	9.431	9.474	EPSD	TCGA;ICGC;COSMIC	5.604	Up-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q9NRL2	BAZ1A	O14757	CHEK1	S960	S961Y	961	Missense	proximal	1	no	9.431	9.413	EPSD	TCGA;ICGC;COSMIC	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q9NRL2	BAZ1A	O14757	CHEK1	S1205	R1209K	1209	Missense	distal	4	no	9.737	9.639	EPSD	TCGA;ICGC	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q9NRL2	BAZ1A	O14757	CHEK1	S1205	R1200C	1200	Missense	distal	-5	no	9.737	9.059	EPSD	TCGA;ICGC;COSMIC	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q9NRL2	BAZ1A	O14757	CHEK1	S1206	R1209K	1209	Missense	distal	3	no	9.311	9.957	EPSD	TCGA;ICGC	5.604	Up-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q9NRL2	BAZ1A	O14757	CHEK1	S1206	R1200C	1200	Missense	distal	-6	no	9.311	9.426	EPSD	TCGA;ICGC;COSMIC	5.604	Up-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q9NRL2	BAZ1A	O14757	CHEK1	S1426	R1423Q	1423	Missense	distal	-3	no	10.205	2.999	EPSD	TCGA;COSMIC	5.604	Loss
CAMK_CAMKL_CHK1_CHEK1_ST	Q9NRL2	BAZ1A	O14757	CHEK1	S1426	G1431E	1431	Missense	distal	5	no	10.205	10.482	EPSD	TCGA;COSMIC	5.604	Up-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q9NRL2	BAZ1A	O14757	CHEK1	S1426	G1431R	1431	Missense	distal	5	no	10.205	10.293	EPSD	TCGA;COSMIC	5.604	Up-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q9NRL2	BAZ1A	O14757	CHEK1	S1540	V1537I	1537	Missense	distal	-3	no	6.375	6.081	EPSD	TCGA;ICGC;COSMIC	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q9NRL2	BAZ1A	O14757	CHEK1	S1540	N1541H	1541	Missense	proximal	1	no	6.375	6.338	EPSD	TCGA;ICGC;COSMIC	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	P54132	BLM	O14757	CHEK1	S42	S48F	48	Missense	distal	6	no	6.851	7.253	EPSD	TCGA;ICGC;COSMIC	5.604	Up-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	P54132	BLM	O14757	CHEK1	S104	D110N	110	Missense	distal	6	no	10.128	10.446	EPSD	TCGA;ICGC;COSMIC	5.604	Up-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	P54132	BLM	O14757	CHEK1	S104	Q100H	100	Missense	distal	-4	no	10.128	9.770	EPSD	TCGA;ICGC;COSMIC	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	P54132	BLM	O14757	CHEK1	S104	Q97H	97	Missense	distal	-7	no	10.128	9.811	EPSD	TCGA;ICGC;COSMIC	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	P54132	BLM	O14757	CHEK1	T182	Q184E	184	Missense	proximal	2	no	10.690	10.805	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	5.604	Up-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	P54132	BLM	O14757	CHEK1	T182	K188R	188	Missense	distal	6	no	10.690	10.778	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	5.604	Up-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	P54132	BLM	O14757	CHEK1	T182	R179I	179	Missense	distal	-3	no	10.690	1.932	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	5.604	Loss
CAMK_CAMKL_CHK1_CHEK1_ST	P54132	BLM	O14757	CHEK1	T182	Q184L	184	Missense	proximal	2	no	10.690	9.862	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	P54132	BLM	O14757	CHEK1	T182	S175I	175	Missense	distal	-7	no	10.690	10.047	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	P54132	BLM	O14757	CHEK1	S269	E265Q	265	Missense	distal	-4	no	9.017	8.974	EPSD	TCGA;ICGC;COSMIC	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	P54132	BLM	O14757	CHEK1	S269	K273R	273	Missense	distal	4	no	9.017	9.116	EPSD	TCGA;ICGC;COSMIC	5.604	Up-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	P54132	BLM	O14757	CHEK1	S269	K273N	273	Missense	distal	4	no	9.017	9.085	EPSD	TCGA;ICGC;COSMIC	5.604	Up-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	P54132	BLM	O14757	CHEK1	T412	N405S	405	Missense	distal	-7	no	6.894	7.432	EPSD	TCGA;ICGC	5.604	Up-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	P54132	BLM	O14757	CHEK1	S434	D433H	433	Missense	proximal	-1	no	7.911	8.068	EPSD	TCGA;ICGC;COSMIC	5.604	Up-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	P54132	BLM	O14757	CHEK1	S434	R431K	431	Missense	distal	-3	no	7.911	4.086	EPSD	TCGA;ICGC;COSMIC	5.604	Loss
CAMK_CAMKL_CHK1_CHEK1_ST	P54132	BLM	O14757	CHEK1	S434	R429K	429	Missense	distal	-5	no	7.911	9.087	EPSD	TCGA;ICGC;COSMIC	5.604	Up-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	P54132	BLM	O14757	CHEK1	S434	P438H	438	Missense	distal	4	no	7.911	7.983	EPSD	TCGA;ICGC	5.604	Up-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	P54132	BLM	O14757	CHEK1	S434	G437V	437	Missense	distal	3	no	7.911	8.337	EPSD	TCGA;ICGC;COSMIC	5.604	Up-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	P54132	BLM	O14757	CHEK1	S539	E546Q	546	Missense	distal	7	no	8.908	8.822	PhosphoSitePlus;EPSD	TCGA;ICGC;COSMIC	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	P54132	BLM	O14757	CHEK1	S539	K535Q	535	Missense	distal	-4	no	8.908	8.967	PhosphoSitePlus;EPSD	TCGA;ICGC;COSMIC	5.604	Up-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	P54132	BLM	O14757	CHEK1	S597	L600F	600	Missense	distal	3	no	5.636	6.258	EPSD	TCGA;ICGC;COSMIC	5.604	Up-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	P54132	BLM	O14757	CHEK1	S602	L600F	600	Missense	proximal	-2	no	7.824	8.009	EPSD	TCGA;ICGC;COSMIC	5.604	Up-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	P54132	BLM	O14757	CHEK1	S646	K653M	653	Missense	distal	7	no	9.083	8.899	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	P54132	BLM	O14757	CHEK1	S646	L647I	647	Missense	proximal	1	no	9.083	9.056	EPSD;PhosphoSitePlus	TCGA;COSMIC	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	P54132	BLM	O14757	CHEK1	S646	R643C	643	Missense	distal	-3	no	9.083	0.991	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	5.604	Loss
CAMK_CAMKL_CHK1_CHEK1_ST	P54132	BLM	O14757	CHEK1	S646	K653N	653	Missense	distal	7	no	9.083	9.144	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	5.604	Up-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	P54132	BLM	O14757	CHEK1	S823	S823C	823	Missense	central	0	yes	6.061	0.000	EPSD	TCGA;ICGC;COSMIC	5.604	Loss
CAMK_CAMKL_CHK1_CHEK1_ST	P54132	BLM	O14757	CHEK1	S823	R818H	818	Missense	distal	-5	no	6.061	3.596	EPSD	TCGA;ICGC;CCLE	5.604	Loss
CAMK_CAMKL_CHK1_CHEK1_ST	P54132	BLM	O14757	CHEK1	S823	M827I	827	Missense	distal	4	no	6.061	6.002	EPSD	TCGA;ICGC;COSMIC	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	P54132	BLM	O14757	CHEK1	S823	S823F	823	Missense	central	0	yes	6.061	0.000	EPSD	TCGA;ICGC;COSMIC	5.604	Loss
CAMK_CAMKL_CHK1_CHEK1_ST	P54132	BLM	O14757	CHEK1	S823	R818C	818	Missense	distal	-5	no	6.061	5.383	EPSD	TCGA;ICGC;COSMIC	5.604	Loss
CAMK_CAMKL_CHK1_CHEK1_ST	P54132	BLM	O14757	CHEK1	S823	P825Q	825	Missense	proximal	2	no	6.061	6.572	EPSD	TCGA;ICGC;COSMIC	5.604	Up-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	P54132	BLM	O14757	CHEK1	S1128	G1134E	1134	Missense	distal	6	no	8.259	7.777	EPSD	TCGA;ICGC;COSMIC	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	P54132	BLM	O14757	CHEK1	S1128	G1132V	1132	Missense	distal	4	no	8.259	8.303	EPSD	TCGA;ICGC;COSMIC	5.604	Up-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	P54132	BLM	O14757	CHEK1	S1254	E1258K	1258	Missense	distal	4	no	5.807	5.801	EPSD	TCGA;ICGC;COSMIC	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	P54132	BLM	O14757	CHEK1	S1254	S1252Y	1252	Missense	proximal	-2	no	5.807	5.920	EPSD	TCGA;ICGC;COSMIC	5.604	Up-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	P54132	BLM	O14757	CHEK1	S1254	D1256E	1256	Missense	proximal	2	no	5.807	5.890	EPSD	TCGA;ICGC;COSMIC	5.604	Up-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	P54132	BLM	O14757	CHEK1	S1254	L1253V	1253	Missense	proximal	-1	no	5.807	5.802	EPSD	TCGA;ICGC	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	P54132	BLM	O14757	CHEK1	S1254	E1258D	1258	Missense	distal	4	no	5.807	5.899	EPSD	TCGA;ICGC;COSMIC	5.604	Up-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	O00716	E2F3	O14757	CHEK1	T181	T181M	181	Missense	central	0	yes	8.888	0.000	EPSD	TCGA;ICGC;COSMIC	5.604	Loss
CAMK_CAMKL_CHK1_CHEK1_ST	O00716	E2F3	O14757	CHEK1	T181	L186R	186	Missense	distal	5	no	8.888	9.029	EPSD	TCGA;ICGC;COSMIC;GDSC;CCLE	5.604	Up-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	O00716	E2F3	O14757	CHEK1	T181	R178W	178	Missense	distal	-3	no	8.888	-24.715	EPSD	TCGA;ICGC	5.604	Loss
CAMK_CAMKL_CHK1_CHEK1_ST	O00716	E2F3	O14757	CHEK1	S235	V239I	239	Missense	distal	4	no	8.306	8.247	EPSD	TCGA;ICGC;COSMIC	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	O00716	E2F3	O14757	CHEK1	S235	K232N	232	Missense	distal	-3	no	8.306	1.764	EPSD	TCGA;ICGC	5.604	Loss
CAMK_CAMKL_CHK1_CHEK1_ST	O00716	E2F3	O14757	CHEK1	S308	R305Q	305	Missense	distal	-3	no	6.273	-0.934	EPSD	TCGA;ICGC;COSMIC	5.604	Loss
CAMK_CAMKL_CHK1_CHEK1_ST	O14757	CHEK1	O14757	CHEK1	S280	G281D	281	Missense	proximal	1	no	10.080	10.167	EPSD	TCGA;ICGC;COSMIC	5.604	Up-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	O14757	CHEK1	O14757	CHEK1	S280	T279I	279	Missense	proximal	-1	no	10.080	9.993	EPSD	TCGA;ICGC;COSMIC	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	O14757	CHEK1	O14757	CHEK1	S280	S284L	284	Missense	distal	4	no	10.080	10.116	EPSD	TCGA;ICGC;COSMIC	5.604	Up-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	O14757	CHEK1	O14757	CHEK1	S291	S288R	288	Missense	distal	-3	no	-0.373	9.323	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	5.604	Gain
CAMK_CAMKL_CHK1_CHEK1_ST	O14757	CHEK1	O14757	CHEK1	S296	Q295E	295	Missense	proximal	-1	no	6.583	6.477	PhosphoSitePlus;EPSD	TCGA;ICGC;COSMIC	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	O14757	CHEK1	O14757	CHEK1	S296	G289V	289	Missense	distal	-7	no	6.583	6.598	PhosphoSitePlus;EPSD	TCGA;ICGC;COSMIC	5.604	Up-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	O14757	CHEK1	O14757	CHEK1	S296	S296F	296	Missense	central	0	yes	6.583	0.000	PhosphoSitePlus;EPSD	TCGA;ICGC;COSMIC	5.604	Loss
CAMK_CAMKL_CHK1_CHEK1_ST	O14757	CHEK1	O14757	CHEK1	S296	N297T	297	Missense	proximal	1	no	6.583	6.593	PhosphoSitePlus;EPSD	TCGA;ICGC	5.604	Up-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	O14757	CHEK1	O14757	CHEK1	S316	E309K	309	Missense	distal	-7	no	5.834	6.531	EPSD;PhosphoSitePlus	TCGA;COSMIC	5.604	Up-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	O14757	CHEK1	O14757	CHEK1	S316	R322H	322	Missense	distal	6	no	5.834	6.122	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	5.604	Up-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	O14757	CHEK1	O14757	CHEK1	T382	R379Q	379	Missense	distal	-3	no	9.696	2.489	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	5.604	Loss
CAMK_CAMKL_CHK1_CHEK1_ST	Q14669	TRIP12	O14757	CHEK1	T54	G61E	61	Missense	distal	7	no	8.431	8.666	EPSD	TCGA;COSMIC	5.604	Up-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q14669	TRIP12	O14757	CHEK1	T54	D48N	48	Missense	distal	-6	no	8.431	8.644	EPSD	TCGA;COSMIC	5.604	Up-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q14669	TRIP12	O14757	CHEK1	T54	D48A	48	Missense	distal	-6	no	8.431	8.477	EPSD	TCGA;COSMIC	5.604	Up-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q14669	TRIP12	O14757	CHEK1	S77	N84D	84	Missense	distal	7	no	8.888	9.050	EPSD	TCGA	5.604	Up-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q14669	TRIP12	O14757	CHEK1	S77	R74H	74	Missense	distal	-3	no	8.888	3.079	EPSD	TCGA;COSMIC;GDSC	5.604	Loss
CAMK_CAMKL_CHK1_CHEK1_ST	Q14669	TRIP12	O14757	CHEK1	S85	S85Y	85	Missense	central	0	yes	7.771	0.000	EPSD	TCGA;COSMIC	5.604	Loss
CAMK_CAMKL_CHK1_CHEK1_ST	Q14669	TRIP12	O14757	CHEK1	S85	N84D	84	Missense	proximal	-1	no	7.771	7.682	EPSD	TCGA	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q14669	TRIP12	O14757	CHEK1	S100	T98I	98	Missense	proximal	-2	no	9.903	9.777	EPSD	TCGA;COSMIC	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q14669	TRIP12	O14757	CHEK1	S100	P107Q	107	Missense	distal	7	no	9.903	10.095	EPSD	TCGA;COSMIC	5.604	Up-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q14669	TRIP12	O14757	CHEK1	S100	N105S	105	Missense	distal	5	no	9.903	9.905	EPSD	TCGA;COSMIC	5.604	Up-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q14669	TRIP12	O14757	CHEK1	S109	P107Q	107	Missense	proximal	-2	no	5.781	5.642	EPSD	TCGA;COSMIC	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q14669	TRIP12	O14757	CHEK1	S109	K112N	112	Missense	distal	3	no	5.781	5.978	EPSD	TCGA;COSMIC	5.604	Up-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q14669	TRIP12	O14757	CHEK1	S109	N105S	105	Missense	distal	-4	no	5.781	5.487	EPSD	TCGA;COSMIC	5.604	Loss
CAMK_CAMKL_CHK1_CHEK1_ST	Q14669	TRIP12	O14757	CHEK1	T152	Q147L	147	Missense	distal	-5	no	4.752	8.125	EPSD	TCGA;COSMIC	5.604	Gain
CAMK_CAMKL_CHK1_CHEK1_ST	Q14669	TRIP12	O14757	CHEK1	S236	R235H	235	Missense	proximal	-1	no	6.191	6.317	EPSD	TCGA;COSMIC	5.604	Up-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q14669	TRIP12	O14757	CHEK1	S238	R235H	235	Missense	distal	-3	no	8.739	2.929	EPSD	TCGA;COSMIC	5.604	Loss
CAMK_CAMKL_CHK1_CHEK1_ST	Q14669	TRIP12	O14757	CHEK1	S246	E248K	248	Missense	proximal	2	no	8.213	8.255	EPSD	TCGA	5.604	Up-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q14669	TRIP12	O14757	CHEK1	S312	R309C	309	Missense	distal	-3	no	7.808	-0.283	EPSD	TCGA;COSMIC	5.604	Loss
CAMK_CAMKL_CHK1_CHEK1_ST	Q14669	TRIP12	O14757	CHEK1	S312	R309H	309	Missense	distal	-3	no	7.808	1.999	EPSD	TCGA;COSMIC	5.604	Loss
CAMK_CAMKL_CHK1_CHEK1_ST	Q14669	TRIP12	O14757	CHEK1	S312	S305Y	305	Missense	distal	-7	no	7.808	6.150	EPSD	TCGA;COSMIC	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q14669	TRIP12	O14757	CHEK1	T329	Q326R	326	Missense	distal	-3	no	0.632	7.839	EPSD	TCGA;COSMIC	5.604	Gain
CAMK_CAMKL_CHK1_CHEK1_ST	Q14669	TRIP12	O14757	CHEK1	S780	N787Y	787	Missense	distal	7	no	8.069	7.325	EPSD	TCGA;COSMIC	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q14669	TRIP12	O14757	CHEK1	S780	P774S	774	Missense	distal	-6	no	8.069	7.972	EPSD	TCGA;COSMIC	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q14669	TRIP12	O14757	CHEK1	S938	T941I	941	Missense	distal	3	no	6.571	6.340	EPSD	TCGA;COSMIC	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q14669	TRIP12	O14757	CHEK1	S987	S983I	983	Missense	distal	-4	no	6.774	6.795	EPSD	TCGA;ICGC	5.604	Up-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q14669	TRIP12	O14757	CHEK1	T1032	K1029E	1029	Missense	distal	-3	no	6.788	3.525	EPSD	TCGA;COSMIC	5.604	Loss
CAMK_CAMKL_CHK1_CHEK1_ST	Q14669	TRIP12	O14757	CHEK1	T1032	T1032I	1032	Missense	central	0	yes	6.788	0.000	EPSD	TCGA;COSMIC	5.604	Loss
CAMK_CAMKL_CHK1_CHEK1_ST	Q14669	TRIP12	O14757	CHEK1	T1032	A1028T	1028	Missense	distal	-4	no	6.788	6.357	EPSD	TCGA;COSMIC	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q14669	TRIP12	O14757	CHEK1	S1078	A1076T	1076	Missense	proximal	-2	no	12.866	13.006	PhosphoSitePlus	TCGA;COSMIC	5.604	Up-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q14669	TRIP12	O14757	CHEK1	T1358	Y1355H	1355	Missense	distal	-3	no	-3.934	7.200	EPSD	TCGA	5.604	Gain
CAMK_CAMKL_CHK1_CHEK1_ST	Q14669	TRIP12	O14757	CHEK1	S1367	Q1361L	1361	Missense	distal	-6	no	8.740	8.763	EPSD	TCGA;COSMIC	5.604	Up-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q14669	TRIP12	O14757	CHEK1	S1367	D1372N	1372	Missense	distal	5	no	8.740	8.651	EPSD	TCGA	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q14669	TRIP12	O14757	CHEK1	T1377	S1381I	1381	Missense	distal	4	no	11.435	11.487	EPSD	TCGA;COSMIC	5.604	Up-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q14669	TRIP12	O14757	CHEK1	T1377	D1378N	1378	Missense	proximal	1	no	11.435	11.328	EPSD	TCGA;COSMIC	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q14669	TRIP12	O14757	CHEK1	T1377	D1372N	1372	Missense	distal	-5	no	11.435	12.704	EPSD	TCGA	5.604	Up-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q14669	TRIP12	O14757	CHEK1	T1377	P1383H	1383	Missense	distal	6	no	11.435	11.192	EPSD	TCGA	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q14669	TRIP12	O14757	CHEK1	T1421	T1424M	1424	Missense	distal	3	no	7.001	7.057	EPSD	TCGA;COSMIC	5.604	Up-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q14669	TRIP12	O14757	CHEK1	T1421	S1427F	1427	Missense	distal	6	no	7.001	7.404	EPSD	TCGA;COSMIC	5.604	Up-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q14669	TRIP12	O14757	CHEK1	T1421	R1416K	1416	Missense	distal	-5	no	7.001	8.176	EPSD	TCGA;COSMIC	5.604	Up-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q9UKI8	TLK1	O14757	CHEK1	S188	L194S	194	Missense	distal	6	no	9.328	8.919	EPSD	TCGA;ICGC;COSMIC	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q9UKI8	TLK1	O14757	CHEK1	S188	P186L	186	Missense	proximal	-2	no	9.328	9.149	EPSD	TCGA;ICGC;COSMIC	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q9UKI8	TLK1	O14757	CHEK1	S188	R185Q	185	Missense	distal	-3	no	9.328	2.121	EPSD	TCGA;ICGC;COSMIC	5.604	Loss
CAMK_CAMKL_CHK1_CHEK1_ST	Q9UKI8	TLK1	O14757	CHEK1	S188	L194F	194	Missense	distal	6	no	9.328	9.321	EPSD	TCGA;COSMIC	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q9UKI8	TLK1	O14757	CHEK1	T353	R349H	349	Missense	distal	-4	no	8.007	7.809	EPSD	TCGA;COSMIC	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q9UKI8	TLK1	O14757	CHEK1	T353	T353R	353	Missense	central	0	yes	8.007	0.000	EPSD	TCGA;ICGC;COSMIC	5.604	Loss
CAMK_CAMKL_CHK1_CHEK1_ST	Q9UKI8	TLK1	O14757	CHEK1	T353	K348T	348	Missense	distal	-5	no	8.007	7.752	EPSD	TCGA;ICGC;COSMIC	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q9UKI8	TLK1	O14757	CHEK1	T353	N356T	356	Missense	distal	3	no	8.007	7.022	EPSD	TCGA;ICGC;COSMIC	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q9UKI8	TLK1	O14757	CHEK1	S679	E686Q	686	Missense	distal	7	no	7.733	7.647	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q9UKI8	TLK1	O14757	CHEK1	S679	L684I	684	Missense	distal	5	no	7.733	7.833	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	5.604	Up-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q9UKI8	TLK1	O14757	CHEK1	S743	S743Y	743	Missense	central	0	yes	8.144	0.000	PhosphoSitePlus;EPSD	TCGA;ICGC;COSMIC;GDSC;CCLE	5.604	Loss
CAMK_CAMKL_CHK1_CHEK1_ST	Q9UKI8	TLK1	O14757	CHEK1	S743	L747P	747	Missense	distal	4	no	8.144	8.247	PhosphoSitePlus;EPSD	TCGA;ICGC;COSMIC	5.604	Up-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q9UKI8	TLK1	O14757	CHEK1	S743	M738V	738	Missense	distal	-5	no	8.144	9.040	PhosphoSitePlus;EPSD	TCGA;ICGC;COSMIC	5.604	Up-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	P49761	CLK3	O14757	CHEK1	S157	Y155C	155	Missense	proximal	-2	no	10.275	10.210	PhosphoSitePlus	TCGA;ICGC;COSMIC	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	P49761	CLK3	O14757	CHEK1	S157	R156H	156	Missense	proximal	-1	no	10.275	10.400	PhosphoSitePlus	TCGA	5.604	Up-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	P49761	CLK3	O14757	CHEK1	S157	R154Q	154	Missense	distal	-3	no	10.275	3.068	PhosphoSitePlus	TCGA	5.604	Loss
CAMK_CAMKL_CHK1_CHEK1_ST	P49761	CLK3	O14757	CHEK1	S173	S173F	173	Missense	central	0	yes	8.724	0.000	EPSD	TCGA;ICGC;COSMIC	5.604	Loss
CAMK_CAMKL_CHK1_CHEK1_ST	P49761	CLK3	O14757	CHEK1	S173	R172S	172	Missense	proximal	-1	no	8.724	8.563	EPSD	TCGA;COSMIC	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	P49761	CLK3	O14757	CHEK1	S175	S173F	173	Missense	proximal	-2	no	8.264	8.554	EPSD	TCGA;ICGC;COSMIC	5.604	Up-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	P49761	CLK3	O14757	CHEK1	S175	R172S	172	Missense	distal	-3	no	8.264	-1.432	EPSD	TCGA;COSMIC	5.604	Loss
CAMK_CAMKL_CHK1_CHEK1_ST	P49761	CLK3	O14757	CHEK1	S186	R187Q	187	Missense	proximal	1	no	13.199	13.208	EPSD	TCGA;ICGC;COSMIC	5.604	Up-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	P49761	CLK3	O14757	CHEK1	S197	R202H	202	Missense	distal	5	no	6.038	6.054	EPSD	TCGA;COSMIC;GDSC;CCLE	5.604	Up-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	P49761	CLK3	O14757	CHEK1	S197	R196W	196	Missense	proximal	-1	no	6.038	6.156	EPSD	TCGA;ICGC;COSMIC	5.604	Up-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	P49761	CLK3	O14757	CHEK1	S197	R196Q	196	Missense	proximal	-1	no	6.038	6.054	EPSD	TCGA;COSMIC	5.604	Up-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	P49761	CLK3	O14757	CHEK1	S197	S195F	195	Missense	proximal	-2	no	6.038	6.328	EPSD	TCGA;ICGC;COSMIC	5.604	Up-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	P49761	CLK3	O14757	CHEK1	S197	R194I	194	Missense	distal	-3	no	6.038	-2.720	EPSD	TCGA;COSMIC	5.604	Loss
CAMK_CAMKL_CHK1_CHEK1_ST	P49761	CLK3	O14757	CHEK1	S197	S197P	197	Missense	central	0	yes	6.038	0.000	EPSD	TCGA;ICGC;COSMIC	5.604	Loss
CAMK_CAMKL_CHK1_CHEK1_ST	P49761	CLK3	O14757	CHEK1	S199	R202H	202	Missense	distal	3	no	9.036	9.067	EPSD	TCGA;COSMIC;GDSC;CCLE	5.604	Up-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	P49761	CLK3	O14757	CHEK1	S199	R196W	196	Missense	distal	-3	no	9.036	-24.567	EPSD	TCGA;ICGC;COSMIC	5.604	Loss
CAMK_CAMKL_CHK1_CHEK1_ST	P49761	CLK3	O14757	CHEK1	S199	R196Q	196	Missense	distal	-3	no	9.036	1.829	EPSD	TCGA;COSMIC	5.604	Loss
CAMK_CAMKL_CHK1_CHEK1_ST	P49761	CLK3	O14757	CHEK1	S199	S195F	195	Missense	distal	-4	no	9.036	8.794	EPSD	TCGA;ICGC;COSMIC	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	P49761	CLK3	O14757	CHEK1	S199	R194I	194	Missense	distal	-5	no	9.036	9.981	EPSD	TCGA;COSMIC	5.604	Up-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	P49761	CLK3	O14757	CHEK1	S199	S197P	197	Missense	proximal	-2	no	9.036	9.320	EPSD	TCGA;ICGC;COSMIC	5.604	Up-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	P49761	CLK3	O14757	CHEK1	S215	R212C	212	Missense	distal	-3	no	9.322	1.231	EPSD	TCGA;COSMIC	5.604	Loss
CAMK_CAMKL_CHK1_CHEK1_ST	P49761	CLK3	O14757	CHEK1	S215	R212L	212	Missense	distal	-3	no	9.322	-9.225	EPSD	TCGA;COSMIC	5.604	Loss
CAMK_CAMKL_CHK1_CHEK1_ST	P49761	CLK3	O14757	CHEK1	S226	Y231C	231	Missense	distal	5	no	9.928	10.035	EPSD	TCGA;COSMIC	5.604	Up-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	P49761	CLK3	O14757	CHEK1	S226	R223Q	223	Missense	distal	-3	no	9.928	2.721	EPSD	TCGA;ICGC;COSMIC	5.604	Loss
CAMK_CAMKL_CHK1_CHEK1_ST	P49761	CLK3	O14757	CHEK1	S243	R242Q	242	Missense	proximal	-1	no	9.239	9.254	EPSD	TCGA;COSMIC	5.604	Up-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	P49761	CLK3	O14757	CHEK1	S243	R250W	250	Missense	distal	7	no	9.239	8.737	EPSD	TCGA	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	P49761	CLK3	O14757	CHEK1	S243	R241W	241	Missense	proximal	-2	no	9.239	9.360	EPSD	TCGA;ICGC;COSMIC	5.604	Up-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	P49761	CLK3	O14757	CHEK1	S243	R241Q	241	Missense	proximal	-2	no	9.239	9.285	EPSD	TCGA;ICGC;COSMIC	5.604	Up-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	P49761	CLK3	O14757	CHEK1	S265	A269T	269	Missense	distal	4	no	10.395	10.213	EPSD	TCGA;ICGC;COSMIC	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	P49761	CLK3	O14757	CHEK1	S265	R262H	262	Missense	distal	-3	no	10.395	4.586	EPSD	TCGA;ICGC;COSMIC	5.604	Loss
CAMK_CAMKL_CHK1_CHEK1_ST	P49761	CLK3	O14757	CHEK1	S267	A269T	269	Missense	proximal	2	no	8.524	7.676	EPSD	TCGA;ICGC;COSMIC	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	P49761	CLK3	O14757	CHEK1	S267	R262H	262	Missense	distal	-5	no	8.524	6.059	EPSD	TCGA;ICGC;COSMIC	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q53H47	SETMAR	O14757	CHEK1	S508	R506Q	506	Missense	proximal	-2	no	9.479	9.525	PhosphoSitePlus	TCGA;ICGC;COSMIC	5.604	Up-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	O75461	E2F6	O14757	CHEK1	S52	R54I	54	Missense	proximal	2	no	6.974	6.563	PhosphoSitePlus;EPSD	TCGA	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	P04637	TP53	O14757	CHEK1	S183	E180K	180	Missense	distal	-3	no	2.591	5.854	EPSD	TCGA;ICGC;COSMIC;CCLE	5.604	Gain
CAMK_CAMKL_CHK1_CHEK1_ST	P04637	TP53	O14757	CHEK1	S269	C275Y	275	Missense	distal	6	no	5.247	5.607	EPSD	TCGA;ICGC;COSMIC;GDSC;CCLE	5.604	Gain
CAMK_CAMKL_CHK1_CHEK1_ST	P04637	TP53	O14757	CHEK1	S269	G266E	266	Missense	distal	-3	no	5.247	5.933	EPSD	TCGA;ICGC;COSMIC;GDSC;CCLE	5.604	Gain
CAMK_CAMKL_CHK1_CHEK1_ST	P04637	TP53	O14757	CHEK1	S269	G266R	266	Missense	distal	-3	no	5.247	13.022	EPSD	TCGA;ICGC;COSMIC;GDSC;CCLE	5.604	Gain
CAMK_CAMKL_CHK1_CHEK1_ST	P04637	TP53	O14757	CHEK1	S378	Q375K	375	Missense	distal	-3	no	3.588	6.970	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	5.604	Gain
CAMK_CAMKL_CHK1_CHEK1_ST	O15350	TP73	O14757	CHEK1	S426	G419W	419	Missense	distal	-7	no	6.018	4.434	EPSD	TCGA;COSMIC	5.604	Loss
CAMK_CAMKL_CHK1_CHEK1_ST	Q12789	GTF3C1	O14757	CHEK1	T508	R505P	505	Missense	distal	-3	no	7.593	0.456	EPSD	TCGA;ICGC;COSMIC	5.604	Loss
CAMK_CAMKL_CHK1_CHEK1_ST	Q12789	GTF3C1	O14757	CHEK1	T508	S501F	501	Missense	distal	-7	no	7.593	5.861	EPSD	TCGA;ICGC;COSMIC	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q12789	GTF3C1	O14757	CHEK1	T508	R505Q	505	Missense	distal	-3	no	7.593	0.386	EPSD	TCGA;ICGC;COSMIC	5.604	Loss
CAMK_CAMKL_CHK1_CHEK1_ST	Q12789	GTF3C1	O14757	CHEK1	S603	E610K	610	Missense	distal	7	no	11.942	11.777	EPSD	TCGA;ICGC;COSMIC;CCLE	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q12789	GTF3C1	O14757	CHEK1	S695	P694A	694	Missense	proximal	-1	no	7.572	7.458	EPSD	TCGA;ICGC;COSMIC	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q12789	GTF3C1	O14757	CHEK1	T725	P731S	731	Missense	distal	6	no	7.270	6.650	EPSD	TCGA;COSMIC	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q12789	GTF3C1	O14757	CHEK1	T725	P729L	729	Missense	distal	4	no	7.270	7.166	EPSD	TCGA;ICGC;COSMIC	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q12789	GTF3C1	O14757	CHEK1	S761	S754N	754	Missense	distal	-7	no	7.852	7.315	EPSD	TCGA;ICGC;COSMIC	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q12789	GTF3C1	O14757	CHEK1	S761	R758I	758	Missense	distal	-3	no	7.852	-0.906	EPSD	TCGA;ICGC	5.604	Loss
CAMK_CAMKL_CHK1_CHEK1_ST	Q12789	GTF3C1	O14757	CHEK1	S836	G840C	840	Missense	distal	4	no	7.266	7.353	EPSD	TCGA;ICGC;COSMIC	5.604	Up-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q12789	GTF3C1	O14757	CHEK1	S836	T831M	831	Missense	distal	-5	no	7.266	4.948	EPSD	TCGA;ICGC	5.604	Loss
CAMK_CAMKL_CHK1_CHEK1_ST	Q12789	GTF3C1	O14757	CHEK1	S836	A839V	839	Missense	distal	3	no	7.266	7.510	EPSD	TCGA;ICGC;COSMIC	5.604	Up-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q12789	GTF3C1	O14757	CHEK1	S845	G840C	840	Missense	distal	-5	no	6.410	5.897	EPSD	TCGA;ICGC;COSMIC	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q12789	GTF3C1	O14757	CHEK1	S845	S845F	845	Missense	central	0	yes	6.410	0.000	EPSD	TCGA;ICGC;COSMIC	5.604	Loss
CAMK_CAMKL_CHK1_CHEK1_ST	Q12789	GTF3C1	O14757	CHEK1	S845	A839V	839	Missense	distal	-6	no	6.410	6.548	EPSD	TCGA;ICGC;COSMIC	5.604	Up-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q12789	GTF3C1	O14757	CHEK1	S1062	D1069N	1069	Missense	distal	7	no	11.732	11.571	EPSD	TCGA;ICGC;COSMIC	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q12789	GTF3C1	O14757	CHEK1	S1063	D1069N	1069	Missense	distal	6	no	7.279	7.597	EPSD	TCGA;ICGC;COSMIC	5.604	Up-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q12789	GTF3C1	O14757	CHEK1	T1158	S1161F	1161	Missense	distal	3	no	9.378	9.566	EPSD	TCGA;ICGC	5.604	Up-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q12789	GTF3C1	O14757	CHEK1	T1158	R1163L	1163	Missense	distal	5	no	9.378	9.237	EPSD	TCGA;ICGC;COSMIC	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q12789	GTF3C1	O14757	CHEK1	T1158	F1159C	1159	Missense	proximal	1	no	9.378	9.399	EPSD	TCGA;ICGC	5.604	Up-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q12789	GTF3C1	O14757	CHEK1	S1168	R1163L	1163	Missense	distal	-5	no	3.990	6.967	EPSD	TCGA;ICGC;COSMIC	5.604	Gain
CAMK_CAMKL_CHK1_CHEK1_ST	Q12789	GTF3C1	O14757	CHEK1	S1173	G1179R	1179	Missense	distal	6	no	9.124	8.999	EPSD	TCGA;ICGC;COSMIC	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q12789	GTF3C1	O14757	CHEK1	S1173	E1180K	1180	Missense	distal	7	no	9.124	8.958	EPSD	TCGA;ICGC;COSMIC	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q12789	GTF3C1	O14757	CHEK1	S1173	E1180G	1180	Missense	distal	7	no	9.124	8.889	EPSD	TCGA;ICGC	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q12789	GTF3C1	O14757	CHEK1	S1202	S1202L	1202	Missense	central	0	yes	9.980	0.000	EPSD	TCGA;ICGC;COSMIC	5.604	Loss
CAMK_CAMKL_CHK1_CHEK1_ST	Q12789	GTF3C1	O14757	CHEK1	S1379	S1380L	1380	Missense	proximal	1	no	7.706	7.697	EPSD	TCGA;ICGC;COSMIC	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q12789	GTF3C1	O14757	CHEK1	S1379	S1385F	1385	Missense	distal	6	no	7.706	8.109	EPSD	TCGA;ICGC;COSMIC	5.604	Up-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q12789	GTF3C1	O14757	CHEK1	S1379	N1386S	1386	Missense	distal	7	no	7.706	7.477	EPSD	TCGA;ICGC	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q12789	GTF3C1	O14757	CHEK1	S1379	K1373R	1373	Missense	distal	-6	no	7.706	7.716	EPSD	TCGA;ICGC;COSMIC	5.604	Up-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q12789	GTF3C1	O14757	CHEK1	S1380	S1380L	1380	Missense	central	0	yes	10.872	0.000	EPSD	TCGA;ICGC;COSMIC	5.604	Loss
CAMK_CAMKL_CHK1_CHEK1_ST	Q12789	GTF3C1	O14757	CHEK1	S1380	S1385F	1385	Missense	distal	5	no	10.872	10.546	EPSD	TCGA;ICGC;COSMIC	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q12789	GTF3C1	O14757	CHEK1	S1380	N1386S	1386	Missense	distal	6	no	10.872	10.737	EPSD	TCGA;ICGC	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q12789	GTF3C1	O14757	CHEK1	S1380	K1373R	1373	Missense	distal	-7	no	10.872	9.692	EPSD	TCGA;ICGC;COSMIC	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q12789	GTF3C1	O14757	CHEK1	S1611	E1618K	1618	Missense	distal	7	no	9.591	9.425	EPSD	TCGA;ICGC;COSMIC	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q12789	GTF3C1	O14757	CHEK1	S1611	D1614G	1614	Missense	distal	3	no	9.591	7.946	EPSD	TCGA;ICGC;COSMIC;GDSC;CCLE	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q12789	GTF3C1	O14757	CHEK1	S1611	D1615V	1615	Missense	distal	4	no	9.591	9.651	EPSD	TCGA;ICGC;COSMIC	5.604	Up-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q12789	GTF3C1	O14757	CHEK1	S1611	E1613K	1613	Missense	proximal	2	no	9.591	9.633	EPSD	TCGA;ICGC;COSMIC	5.604	Up-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q12789	GTF3C1	O14757	CHEK1	S1611	G1610D	1610	Missense	proximal	-1	no	9.591	9.542	EPSD	TCGA;ICGC;COSMIC	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q12789	GTF3C1	O14757	CHEK1	S1767	E1761A	1761	Missense	distal	-6	no	13.121	13.117	EPSD	TCGA;ICGC;COSMIC	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q12789	GTF3C1	O14757	CHEK1	S1841	P1836L	1836	Missense	distal	-5	no	4.151	8.857	EPSD	TCGA;ICGC	5.604	Gain
CAMK_CAMKL_CHK1_CHEK1_ST	Q12789	GTF3C1	O14757	CHEK1	S1842	E1848K	1848	Missense	distal	6	no	7.120	7.389	EPSD	TCGA;ICGC;COSMIC;CCLE	5.604	Up-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q12789	GTF3C1	O14757	CHEK1	S1842	P1846L	1846	Missense	distal	4	no	7.120	7.016	EPSD	TCGA;ICGC;COSMIC	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q12789	GTF3C1	O14757	CHEK1	S1842	P1836L	1836	Missense	distal	-6	no	7.120	7.046	EPSD	TCGA;ICGC	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q12789	GTF3C1	O14757	CHEK1	S1842	S1845N	1845	Missense	distal	3	no	7.120	7.961	EPSD	TCGA;ICGC	5.604	Up-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q12789	GTF3C1	O14757	CHEK1	S1865	R1863H	1863	Missense	proximal	-2	no	10.048	10.113	EPSD	TCGA;ICGC;COSMIC	5.604	Up-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q12789	GTF3C1	O14757	CHEK1	S1865	R1863C	1863	Missense	proximal	-2	no	10.048	9.996	EPSD	TCGA;ICGC;COSMIC	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q12789	GTF3C1	O14757	CHEK1	S1865	R1858W	1858	Missense	distal	-7	no	10.048	8.502	EPSD	TCGA;ICGC;COSMIC	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q5T8P6	RBM26	O14757	CHEK1	S15	F10L	10	Missense	distal	-5	no	2.378	5.941	EPSD	TCGA;ICGC;COSMIC	5.604	Gain
CAMK_CAMKL_CHK1_CHEK1_ST	Q5T8P6	RBM26	O14757	CHEK1	S164	P159T	159	Missense	distal	-5	no	4.783	7.434	EPSD	TCGA;ICGC;COSMIC	5.604	Gain
CAMK_CAMKL_CHK1_CHEK1_ST	Q5T8P6	RBM26	O14757	CHEK1	S176	R175W	175	Missense	proximal	-1	no	8.076	8.194	EPSD	TCGA;ICGC;COSMIC	5.604	Up-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q5T8P6	RBM26	O14757	CHEK1	S176	R175Q	175	Missense	proximal	-1	no	8.076	8.092	EPSD	TCGA;ICGC;COSMIC	5.604	Up-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q5T8P6	RBM26	O14757	CHEK1	S176	R183Q	183	Missense	distal	7	no	8.076	8.231	EPSD	TCGA;ICGC;COSMIC;GDSC;CCLE	5.604	Up-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q5T8P6	RBM26	O14757	CHEK1	S178	R175W	175	Missense	distal	-3	no	11.077	-22.526	EPSD	TCGA;ICGC;COSMIC	5.604	Loss
CAMK_CAMKL_CHK1_CHEK1_ST	Q5T8P6	RBM26	O14757	CHEK1	S178	R185Q	185	Missense	distal	7	no	11.077	11.232	EPSD	TCGA;ICGC;COSMIC	5.604	Up-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q5T8P6	RBM26	O14757	CHEK1	S178	R175Q	175	Missense	distal	-3	no	11.077	3.870	EPSD	TCGA;ICGC;COSMIC	5.604	Loss
CAMK_CAMKL_CHK1_CHEK1_ST	Q5T8P6	RBM26	O14757	CHEK1	S178	R183Q	183	Missense	distal	5	no	11.077	11.153	EPSD	TCGA;ICGC;COSMIC;GDSC;CCLE	5.604	Up-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q5T8P6	RBM26	O14757	CHEK1	S180	R175W	175	Missense	distal	-5	no	10.411	9.552	EPSD	TCGA;ICGC;COSMIC	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q5T8P6	RBM26	O14757	CHEK1	S180	R185Q	185	Missense	distal	5	no	10.411	10.486	EPSD	TCGA;ICGC;COSMIC	5.604	Up-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q5T8P6	RBM26	O14757	CHEK1	S180	R175Q	175	Missense	distal	-5	no	10.411	10.015	EPSD	TCGA;ICGC;COSMIC	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q5T8P6	RBM26	O14757	CHEK1	S180	R183Q	183	Missense	distal	3	no	10.411	11.473	EPSD	TCGA;ICGC;COSMIC;GDSC;CCLE	5.604	Up-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q5T8P6	RBM26	O14757	CHEK1	S184	R185Q	185	Missense	proximal	1	no	9.977	9.985	EPSD	TCGA;ICGC;COSMIC	5.604	Up-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q5T8P6	RBM26	O14757	CHEK1	S184	E190D	190	Missense	distal	6	no	9.977	10.063	EPSD	TCGA;ICGC;COSMIC	5.604	Up-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q5T8P6	RBM26	O14757	CHEK1	S184	R183Q	183	Missense	proximal	-1	no	9.977	9.992	EPSD	TCGA;ICGC;COSMIC;GDSC;CCLE	5.604	Up-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q5T8P6	RBM26	O14757	CHEK1	S186	R185Q	185	Missense	proximal	-1	no	9.794	9.810	EPSD	TCGA;ICGC;COSMIC	5.604	Up-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q5T8P6	RBM26	O14757	CHEK1	S186	E190D	190	Missense	distal	4	no	9.794	9.886	EPSD	TCGA;ICGC;COSMIC	5.604	Up-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q5T8P6	RBM26	O14757	CHEK1	S186	R183Q	183	Missense	distal	-3	no	9.794	2.587	EPSD	TCGA;ICGC;COSMIC;GDSC;CCLE	5.604	Loss
CAMK_CAMKL_CHK1_CHEK1_ST	Q5T8P6	RBM26	O14757	CHEK1	S188	R185Q	185	Missense	distal	-3	no	9.428	2.221	EPSD	TCGA;ICGC;COSMIC	5.604	Loss
CAMK_CAMKL_CHK1_CHEK1_ST	Q5T8P6	RBM26	O14757	CHEK1	S188	E190D	190	Missense	proximal	2	no	9.428	9.345	EPSD	TCGA;ICGC;COSMIC	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q5T8P6	RBM26	O14757	CHEK1	S188	R183Q	183	Missense	distal	-5	no	9.428	9.032	EPSD	TCGA;ICGC;COSMIC;GDSC;CCLE	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q5T8P6	RBM26	O14757	CHEK1	T493	S496F	496	Missense	distal	3	no	5.819	6.007	EPSD	TCGA;ICGC;COSMIC	5.604	Up-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q5T8P6	RBM26	O14757	CHEK1	T493	G495S	495	Missense	proximal	2	no	5.819	5.884	EPSD	TCGA;ICGC;COSMIC	5.604	Up-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q5T8P6	RBM26	O14757	CHEK1	S608	T615A	615	Missense	distal	7	no	7.751	7.868	EPSD	TCGA;ICGC	5.604	Up-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	P16989	YBX3	O14757	CHEK1	T112	E114K	114	Missense	proximal	2	no	11.798	11.839	PhosphoSitePlus	TCGA;ICGC;COSMIC	5.604	Up-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	P16989	YBX3	O14757	CHEK1	T112	K113N	113	Missense	proximal	1	no	11.798	11.769	PhosphoSitePlus	TCGA;ICGC	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	P16989	YBX3	O14757	CHEK1	T112	N108H	108	Missense	distal	-4	no	11.798	11.614	PhosphoSitePlus	TCGA;ICGC;COSMIC	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	P16989	YBX3	O14757	CHEK1	T112	F106C	106	Missense	distal	-6	no	11.798	11.559	PhosphoSitePlus	TCGA;ICGC;COSMIC	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	P16989	YBX3	O14757	CHEK1	S203	D208Y	208	Missense	distal	5	no	6.827	6.286	EPSD	TCGA;ICGC;COSMIC	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	P16989	YBX3	O14757	CHEK1	S217	R220Q	220	Missense	distal	3	no	9.466	10.528	EPSD	TCGA;ICGC	5.604	Up-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	P16989	YBX3	O14757	CHEK1	T286	P280L	280	Missense	distal	-6	no	6.117	6.043	EPSD	TCGA;COSMIC	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	P16989	YBX3	O14757	CHEK1	T286	V281A	281	Missense	distal	-5	no	6.117	3.677	EPSD	TCGA;COSMIC	5.604	Loss
CAMK_CAMKL_CHK1_CHEK1_ST	P16989	YBX3	O14757	CHEK1	T286	R288H	288	Missense	proximal	2	no	6.117	6.135	EPSD	TCGA;COSMIC	5.604	Up-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	P16989	YBX3	O14757	CHEK1	S293	R300Q	300	Missense	distal	7	no	11.199	11.354	EPSD	TCGA	5.604	Up-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	P16989	YBX3	O14757	CHEK1	S293	R288H	288	Missense	distal	-5	no	11.199	8.734	EPSD	TCGA;COSMIC	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	P16989	YBX3	O14757	CHEK1	S293	R298H	298	Missense	distal	5	no	11.199	11.215	EPSD	TCGA;COSMIC;CCLE	5.604	Up-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	P16989	YBX3	O14757	CHEK1	S318	E312D	312	Missense	distal	-6	no	7.050	7.000	EPSD	TCGA;COSMIC	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q27J81	INF2	O14757	CHEK1	S574	R578C	578	Missense	distal	4	no	7.239	7.342	PhosphoSitePlus	TCGA;ICGC;COSMIC	5.604	Up-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q27J81	INF2	O14757	CHEK1	S574	P573S	573	Missense	proximal	-1	no	7.239	6.792	PhosphoSitePlus	TCGA;ICGC;COSMIC	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q27J81	INF2	O14757	CHEK1	S586	A592D	592	Missense	distal	6	no	7.871	7.299	EPSD	TCGA;ICGC;COSMIC	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q27J81	INF2	O14757	CHEK1	S586	A592T	592	Missense	distal	6	no	7.871	7.793	EPSD	TCGA;ICGC;COSMIC	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q27J81	INF2	O14757	CHEK1	S586	P590S	590	Missense	distal	4	no	7.871	7.731	EPSD	TCGA;ICGC;COSMIC	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q27J81	INF2	O14757	CHEK1	S607	S607F	607	Missense	central	0	yes	8.081	0.000	EPSD	TCGA;ICGC	5.604	Loss
CAMK_CAMKL_CHK1_CHEK1_ST	Q27J81	INF2	O14757	CHEK1	S855	E851K	851	Missense	distal	-4	no	12.364	12.261	EPSD	TCGA;ICGC;COSMIC	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q27J81	INF2	O14757	CHEK1	S855	V858M	858	Missense	distal	3	no	12.364	11.938	EPSD	TCGA;ICGC;COSMIC	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q27J81	INF2	O14757	CHEK1	S855	S857F	857	Missense	proximal	2	no	12.364	12.219	EPSD	TCGA;ICGC;COSMIC	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q27J81	INF2	O14757	CHEK1	S855	R852Q	852	Missense	distal	-3	no	12.364	5.157	EPSD	TCGA;ICGC;COSMIC	5.604	Loss
CAMK_CAMKL_CHK1_CHEK1_ST	Q27J81	INF2	O14757	CHEK1	S1077	R1075H	1075	Missense	proximal	-2	no	12.154	12.219	EPSD	TCGA;ICGC;COSMIC	5.604	Up-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q27J81	INF2	O14757	CHEK1	S1077	R1075C	1075	Missense	proximal	-2	no	12.154	12.103	EPSD	TCGA;ICGC	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q27J81	INF2	O14757	CHEK1	S1117	L1114H	1114	Missense	distal	-3	no	-5.236	7.502	EPSD	TCGA;ICGC;COSMIC	5.604	Gain
CAMK_CAMKL_CHK1_CHEK1_ST	Q27J81	INF2	O14757	CHEK1	S1147	E1144K	1144	Missense	distal	-3	no	3.249	6.512	EPSD	TCGA;ICGC;COSMIC	5.604	Gain
CAMK_CAMKL_CHK1_CHEK1_ST	Q27J81	INF2	O14757	CHEK1	S1194	A1197V	1197	Missense	distal	3	no	8.336	8.580	EPSD	TCGA;ICGC;COSMIC;GDSC;CCLE	5.604	Up-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q27J81	INF2	O14757	CHEK1	S1227	V1233A	1233	Missense	distal	6	no	9.118	9.230	EPSD	TCGA;ICGC;COSMIC	5.604	Up-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q27J81	INF2	O14757	CHEK1	S1227	R1225C	1225	Missense	proximal	-2	no	9.118	9.066	EPSD	TCGA;ICGC;COSMIC	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q27J81	INF2	O14757	CHEK1	S1229	V1233A	1233	Missense	distal	4	no	6.137	6.220	EPSD	TCGA;ICGC;COSMIC	5.604	Up-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q27J81	INF2	O14757	CHEK1	S1229	R1225C	1225	Missense	distal	-4	no	6.137	5.763	EPSD	TCGA;ICGC;COSMIC	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	P30304	CDC25A	O14757	CHEK1	S76	S69T	69	Missense	distal	-7	no	13.331	12.464	PhosphoSitePlus;EPSD	TCGA;ICGC;COSMIC	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	P30304	CDC25A	O14757	CHEK1	S76	R73K	73	Missense	distal	-3	no	13.331	9.506	PhosphoSitePlus;EPSD	TCGA;ICGC;COSMIC	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	P30304	CDC25A	O14757	CHEK1	S76	N70S	70	Missense	distal	-6	no	13.331	13.290	PhosphoSitePlus;EPSD	TCGA;ICGC;COSMIC	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	P30304	CDC25A	O14757	CHEK1	S76	E78K	78	Missense	proximal	2	no	13.331	13.373	PhosphoSitePlus;EPSD	TCGA;ICGC;COSMIC	5.604	Up-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	P30304	CDC25A	O14757	CHEK1	S107	L113F	113	Missense	distal	6	no	7.848	7.841	EPSD	TCGA;ICGC;COSMIC	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	P30304	CDC25A	O14757	CHEK1	S124	R121S	121	Missense	distal	-3	no	10.290	0.594	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	5.604	Loss
CAMK_CAMKL_CHK1_CHEK1_ST	P30304	CDC25A	O14757	CHEK1	S124	L119V	119	Missense	distal	-5	no	10.290	6.813	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	P30304	CDC25A	O14757	CHEK1	S124	P117S	117	Missense	distal	-7	no	10.290	10.960	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	5.604	Up-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	P30304	CDC25A	O14757	CHEK1	S124	D125N	125	Missense	proximal	1	no	10.290	10.182	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	P30304	CDC25A	O14757	CHEK1	S124	L127V	127	Missense	distal	3	no	10.290	11.062	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	5.604	Up-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	P30304	CDC25A	O14757	CHEK1	S293	S298N	298	Missense	distal	5	no	9.771	9.769	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	P30304	CDC25A	O14757	CHEK1	S505	S505N	505	Missense	central	0	yes	7.469	0.000	EPSD	TCGA;ICGC;COSMIC	5.604	Loss
CAMK_CAMKL_CHK1_CHEK1_ST	P30304	CDC25A	O14757	CHEK1	T507	S505N	505	Missense	proximal	-2	no	6.453	6.642	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	5.604	Up-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	P46013	MKI67	O14757	CHEK1	S166	D173E	173	Missense	distal	7	no	8.077	8.020	EPSD	TCGA;ICGC;COSMIC	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	P46013	MKI67	O14757	CHEK1	S166	D173H	173	Missense	distal	7	no	8.077	7.486	EPSD	TCGA;ICGC;COSMIC	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	P46013	MKI67	O14757	CHEK1	S166	K160R	160	Missense	distal	-6	no	8.077	8.087	EPSD	TCGA;ICGC;COSMIC	5.604	Up-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	P46013	MKI67	O14757	CHEK1	S166	D165H	165	Missense	proximal	-1	no	8.077	8.235	EPSD	TCGA;ICGC;COSMIC	5.604	Up-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	P46013	MKI67	O14757	CHEK1	S166	V162I	162	Missense	distal	-4	no	8.077	7.797	EPSD	TCGA;ICGC;COSMIC	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	P46013	MKI67	O14757	CHEK1	S166	A168V	168	Missense	proximal	2	no	8.077	7.515	EPSD	TCGA;ICGC;COSMIC	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	P46013	MKI67	O14757	CHEK1	S166	A168T	168	Missense	proximal	2	no	8.077	7.229	EPSD	TCGA;ICGC;COSMIC	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	P46013	MKI67	O14757	CHEK1	S166	A168S	168	Missense	proximal	2	no	8.077	7.621	EPSD	TCGA;ICGC;COSMIC	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	P46013	MKI67	O14757	CHEK1	T167	V162I	162	Missense	distal	-5	no	4.771	6.217	EPSD	TCGA;ICGC;COSMIC	5.604	Gain
CAMK_CAMKL_CHK1_CHEK1_ST	P46013	MKI67	O14757	CHEK1	S296	R290C	290	Missense	distal	-6	no	11.621	11.736	EPSD	TCGA;ICGC;COSMIC	5.604	Up-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	P46013	MKI67	O14757	CHEK1	S296	R293I	293	Missense	distal	-3	no	11.621	2.863	EPSD	TCGA;ICGC;COSMIC	5.604	Loss
CAMK_CAMKL_CHK1_CHEK1_ST	P46013	MKI67	O14757	CHEK1	S296	S296Y	296	Missense	central	0	yes	11.621	0.000	EPSD	TCGA;ICGC;COSMIC	5.604	Loss
CAMK_CAMKL_CHK1_CHEK1_ST	P46013	MKI67	O14757	CHEK1	S330	Q327K	327	Missense	distal	-3	no	2.814	6.195	EPSD	TCGA;ICGC;COSMIC	5.604	Gain
CAMK_CAMKL_CHK1_CHEK1_ST	P46013	MKI67	O14757	CHEK1	S374	R372T	372	Missense	proximal	-2	no	7.227	7.382	EPSD	TCGA;ICGC;COSMIC	5.604	Up-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	P46013	MKI67	O14757	CHEK1	S374	G378C	378	Missense	distal	4	no	7.227	7.314	EPSD	TCGA;ICGC;COSMIC	5.604	Up-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	P46013	MKI67	O14757	CHEK1	S374	Y367C	367	Missense	distal	-7	no	7.227	7.898	EPSD	TCGA;ICGC;COSMIC	5.604	Up-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	P46013	MKI67	O14757	CHEK1	S374	R372G	372	Missense	proximal	-2	no	7.227	7.261	EPSD	TCGA;ICGC;COSMIC	5.604	Up-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	P46013	MKI67	O14757	CHEK1	S396	A403P	403	Missense	distal	7	no	9.227	9.234	EPSD	TCGA;ICGC;COSMIC	5.604	Up-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	P46013	MKI67	O14757	CHEK1	T401	D407H	407	Missense	distal	6	no	9.023	9.583	EPSD	TCGA;ICGC;COSMIC	5.604	Up-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	P46013	MKI67	O14757	CHEK1	T401	A403P	403	Missense	proximal	2	no	9.023	8.491	EPSD	TCGA;ICGC;COSMIC	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	P46013	MKI67	O14757	CHEK1	S507	S507F	507	Missense	central	0	yes	9.465	0.000	EPSD	TCGA;COSMIC	5.604	Loss
CAMK_CAMKL_CHK1_CHEK1_ST	P46013	MKI67	O14757	CHEK1	S507	R503I	503	Missense	distal	-4	no	9.465	9.177	EPSD	TCGA	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	P46013	MKI67	O14757	CHEK1	S507	R513I	513	Missense	distal	6	no	9.465	9.420	EPSD	TCGA;COSMIC	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	P46013	MKI67	O14757	CHEK1	S563	V569A	569	Missense	distal	6	no	6.510	6.622	EPSD	TCGA;COSMIC	5.604	Up-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	P46013	MKI67	O14757	CHEK1	S598	A591G	591	Missense	distal	-7	no	9.987	9.316	EPSD	TCGA	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	P46013	MKI67	O14757	CHEK1	S598	R596H	596	Missense	proximal	-2	no	9.987	10.052	EPSD	TCGA;COSMIC	5.604	Up-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	P46013	MKI67	O14757	CHEK1	S598	R596C	596	Missense	proximal	-2	no	9.987	9.936	EPSD	TCGA;COSMIC	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	P46013	MKI67	O14757	CHEK1	T694	V699E	699	Missense	distal	5	no	10.172	10.343	EPSD	TCGA;COSMIC	5.604	Up-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	P46013	MKI67	O14757	CHEK1	S853	D860H	860	Missense	distal	7	no	9.469	8.878	EPSD	TCGA;COSMIC	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	P46013	MKI67	O14757	CHEK1	S853	S853F	853	Missense	central	0	yes	9.469	0.000	EPSD	TCGA	5.604	Loss
CAMK_CAMKL_CHK1_CHEK1_ST	P46013	MKI67	O14757	CHEK1	T1335	K1330N	1330	Missense	distal	-5	no	9.811	8.918	EPSD	TCGA;COSMIC	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	P46013	MKI67	O14757	CHEK1	T1335	Q1334H	1334	Missense	proximal	-1	no	9.811	9.922	EPSD	TCGA;COSMIC	5.604	Up-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	P46013	MKI67	O14757	CHEK1	T1335	E1339K	1339	Missense	distal	4	no	9.811	9.805	EPSD	TCGA;COSMIC	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	P46013	MKI67	O14757	CHEK1	T1335	P1336A	1336	Missense	proximal	1	no	9.811	9.866	EPSD	TCGA;COSMIC	5.604	Up-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	P46013	MKI67	O14757	CHEK1	T1335	E1338K	1338	Missense	distal	3	no	9.811	8.995	EPSD	TCGA;COSMIC	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	P46013	MKI67	O14757	CHEK1	T1335	G1328S	1328	Missense	distal	-7	no	9.811	10.033	EPSD	TCGA;COSMIC;CCLE	5.604	Up-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	P46013	MKI67	O14757	CHEK1	T1335	R1331K	1331	Missense	distal	-4	no	9.811	9.912	EPSD	TCGA;COSMIC	5.604	Up-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	P46013	MKI67	O14757	CHEK1	T1335	P1336S	1336	Missense	proximal	1	no	9.811	9.848	EPSD	TCGA;COSMIC	5.604	Up-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	P46013	MKI67	O14757	CHEK1	T1335	P1333A	1333	Missense	proximal	-2	no	9.811	9.642	EPSD	TCGA;COSMIC	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	P46013	MKI67	O14757	CHEK1	T1335	Q1341H	1341	Missense	distal	6	no	9.811	10.106	EPSD	TCGA;COSMIC	5.604	Up-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	P46013	MKI67	O14757	CHEK1	T1531	A1526T	1526	Missense	distal	-5	no	2.854	6.714	EPSD	TCGA;COSMIC	5.604	Gain
CAMK_CAMKL_CHK1_CHEK1_ST	P46013	MKI67	O14757	CHEK1	S1533	M1538V	1538	Missense	distal	5	no	12.861	12.888	EPSD	TCGA	5.604	Up-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	P46013	MKI67	O14757	CHEK1	S1533	A1526T	1526	Missense	distal	-7	no	12.861	11.544	EPSD	TCGA;COSMIC	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	P46013	MKI67	O14757	CHEK1	S1533	A1534V	1534	Missense	proximal	1	no	12.861	12.837	EPSD	TCGA;COSMIC	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	P46013	MKI67	O14757	CHEK1	S1533	H1539R	1539	Missense	distal	6	no	12.861	12.573	EPSD	TCGA;COSMIC	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	P46013	MKI67	O14757	CHEK1	T1577	K1572N	1572	Missense	distal	-5	no	11.310	10.416	EPSD	TCGA;COSMIC	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	P46013	MKI67	O14757	CHEK1	T1577	R1574W	1574	Missense	distal	-3	no	11.310	-22.293	EPSD	TCGA;COSMIC	5.604	Loss
CAMK_CAMKL_CHK1_CHEK1_ST	P46013	MKI67	O14757	CHEK1	T1601	D1608N	1608	Missense	distal	7	no	7.610	7.448	EPSD	TCGA;COSMIC	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	P46013	MKI67	O14757	CHEK1	T1601	M1605I	1605	Missense	distal	4	no	7.610	7.551	EPSD	TCGA;COSMIC;GDSC;CCLE	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	P46013	MKI67	O14757	CHEK1	T1601	R1598Q	1598	Missense	distal	-3	no	7.610	0.403	EPSD	TCGA;COSMIC	5.604	Loss
CAMK_CAMKL_CHK1_CHEK1_ST	P46013	MKI67	O14757	CHEK1	T1601	H1600R	1600	Missense	proximal	-1	no	7.610	7.485	EPSD	TCGA;COSMIC	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	P46013	MKI67	O14757	CHEK1	T1635	K1634N	1634	Missense	proximal	-1	no	7.087	7.293	EPSD	TCGA;COSMIC	5.604	Up-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	P46013	MKI67	O14757	CHEK1	T1635	T1635A	1635	Missense	central	0	yes	7.087	0.000	EPSD	TCGA;COSMIC	5.604	Loss
CAMK_CAMKL_CHK1_CHEK1_ST	P46013	MKI67	O14757	CHEK1	T1764	L1759I	1759	Missense	distal	-5	no	9.501	7.470	PhosphoSitePlus	TCGA	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	P46013	MKI67	O14757	CHEK1	T1943	A1948V	1948	Missense	distal	5	no	9.129	9.025	EPSD	TCGA;COSMIC	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	P46013	MKI67	O14757	CHEK1	T1943	Q1942H	1942	Missense	proximal	-1	no	9.129	9.239	EPSD	TCGA	5.604	Up-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	P46013	MKI67	O14757	CHEK1	S2173	G2176D	2176	Missense	distal	3	no	5.584	7.229	EPSD	TCGA	5.604	Gain
CAMK_CAMKL_CHK1_CHEK1_ST	P46013	MKI67	O14757	CHEK1	S2261	G2263W	2263	Missense	proximal	2	no	13.599	13.394	EPSD	TCGA;COSMIC	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	P46013	MKI67	O14757	CHEK1	S2261	S2261L	2261	Missense	central	0	yes	13.599	0.000	EPSD	TCGA;COSMIC	5.604	Loss
CAMK_CAMKL_CHK1_CHEK1_ST	P46013	MKI67	O14757	CHEK1	S2261	A2265V	2265	Missense	distal	4	no	13.599	13.517	EPSD	TCGA	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	P46013	MKI67	O14757	CHEK1	S2261	R2258Q	2258	Missense	distal	-3	no	13.599	6.392	EPSD	TCGA;GDSC;CCLE	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	P46013	MKI67	O14757	CHEK1	T2333	T2332M	2332	Missense	proximal	-1	no	6.417	6.423	EPSD	TCGA;COSMIC	5.604	Up-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	P46013	MKI67	O14757	CHEK1	S2382	G2384D	2384	Missense	proximal	2	no	9.988	10.519	EPSD	TCGA;COSMIC	5.604	Up-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	P46013	MKI67	O14757	CHEK1	S2382	R2377K	2377	Missense	distal	-5	no	9.988	11.163	EPSD	TCGA;COSMIC	5.604	Up-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	P46013	MKI67	O14757	CHEK1	S2382	G2384V	2384	Missense	proximal	2	no	9.988	9.946	EPSD	TCGA;COSMIC	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	P46013	MKI67	O14757	CHEK1	S2382	R2379Q	2379	Missense	distal	-3	no	9.988	2.781	EPSD	TCGA;COSMIC	5.604	Loss
CAMK_CAMKL_CHK1_CHEK1_ST	P46013	MKI67	O14757	CHEK1	T2577	E2573K	2573	Missense	distal	-4	no	6.245	6.143	EPSD	TCGA;COSMIC	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	P46013	MKI67	O14757	CHEK1	T2577	H2571Y	2571	Missense	distal	-6	no	6.245	6.378	EPSD	TCGA;COSMIC	5.604	Up-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	P46013	MKI67	O14757	CHEK1	T2577	K2583Q	2583	Missense	distal	6	no	6.245	6.327	EPSD	TCGA;COSMIC	5.604	Up-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	P46013	MKI67	O14757	CHEK1	S2920	Q2913P	2913	Missense	distal	-7	no	5.683	5.015	EPSD	TCGA;COSMIC	5.604	Loss
CAMK_CAMKL_CHK1_CHEK1_ST	P46013	MKI67	O14757	CHEK1	S3041	V3046F	3046	Missense	distal	5	no	11.028	10.788	EPSD	TCGA	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	P46013	MKI67	O14757	CHEK1	S3041	E3043K	3043	Missense	proximal	2	no	11.028	11.070	EPSD	TCGA;COSMIC;CCLE	5.604	Up-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	P46013	MKI67	O14757	CHEK1	S3128	E3121K	3121	Missense	distal	-7	no	5.334	6.031	EPSD	TCGA;COSMIC	5.604	Gain
CAMK_CAMKL_CHK1_CHEK1_ST	P46013	MKI67	O14757	CHEK1	S3249	R3248T	3248	Missense	proximal	-1	no	8.179	8.222	EPSD	TCGA;COSMIC	5.604	Up-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	P46013	MKI67	O14757	CHEK1	S3249	S3249R	3249	Missense	central	0	yes	8.179	0.000	EPSD	TCGA;COSMIC	5.604	Loss
CAMK_CAMKL_CHK1_CHEK1_ST	Q14186	TFDP1	O14757	CHEK1	S120	F119L	119	Missense	proximal	-1	no	9.814	9.800	EPSD	TCGA;ICGC	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q14186	TFDP1	O14757	CHEK1	S120	G113D	113	Missense	distal	-7	no	9.814	9.805	EPSD	TCGA;ICGC;COSMIC	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q14186	TFDP1	O14757	CHEK1	S120	L116P	116	Missense	distal	-4	no	9.814	9.998	EPSD	TCGA;ICGC;COSMIC	5.604	Up-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q14186	TFDP1	O14757	CHEK1	S120	K126E	126	Missense	distal	6	no	9.814	9.544	EPSD	TCGA;ICGC;COSMIC	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q14186	TFDP1	O14757	CHEK1	S120	R117W	117	Missense	distal	-3	no	9.814	-23.789	EPSD	TCGA;ICGC;COSMIC	5.604	Loss
CAMK_CAMKL_CHK1_CHEK1_ST	Q14186	TFDP1	O14757	CHEK1	S120	E125D	125	Missense	distal	5	no	9.814	9.815	EPSD	TCGA;ICGC;COSMIC	5.604	Up-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q14186	TFDP1	O14757	CHEK1	S120	E125K	125	Missense	distal	5	no	9.814	9.749	EPSD	TCGA;ICGC;COSMIC	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q14186	TFDP1	O14757	CHEK1	S120	L116I	116	Missense	distal	-4	no	9.814	9.782	EPSD	TCGA;ICGC	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q14186	TFDP1	O14757	CHEK1	T132	R129S	129	Missense	distal	-3	no	6.695	-3.001	EPSD	TCGA;ICGC;COSMIC	5.604	Loss
CAMK_CAMKL_CHK1_CHEK1_ST	Q14186	TFDP1	O14757	CHEK1	T132	Q128P	128	Missense	distal	-4	no	6.695	6.463	EPSD	TCGA;ICGC;COSMIC	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q14186	TFDP1	O14757	CHEK1	T132	K126E	126	Missense	distal	-6	no	6.695	6.663	EPSD	TCGA;ICGC;COSMIC	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q14186	TFDP1	O14757	CHEK1	T132	E137K	137	Missense	distal	5	no	6.695	6.630	EPSD	TCGA;ICGC;COSMIC	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q14186	TFDP1	O14757	CHEK1	T132	E125D	125	Missense	distal	-7	no	6.695	6.242	EPSD	TCGA;ICGC;COSMIC	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q14186	TFDP1	O14757	CHEK1	T132	E125K	125	Missense	distal	-7	no	6.695	7.392	EPSD	TCGA;ICGC;COSMIC	5.604	Up-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q14186	TFDP1	O14757	CHEK1	T133	R129S	129	Missense	distal	-4	no	7.856	7.548	EPSD	TCGA;ICGC;COSMIC	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q14186	TFDP1	O14757	CHEK1	T133	Q128P	128	Missense	distal	-5	no	7.856	6.522	EPSD	TCGA;ICGC;COSMIC	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q14186	TFDP1	O14757	CHEK1	T133	K126E	126	Missense	distal	-7	no	7.856	7.158	EPSD	TCGA;ICGC;COSMIC	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q14186	TFDP1	O14757	CHEK1	T133	E137K	137	Missense	distal	4	no	7.856	7.850	EPSD	TCGA;ICGC;COSMIC	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q14186	TFDP1	O14757	CHEK1	S147	F146C	146	Missense	proximal	-1	no	8.124	8.047	EPSD	TCGA;ICGC;COSMIC	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q14186	TFDP1	O14757	CHEK1	T388	G394R	394	Missense	distal	6	no	5.810	5.686	EPSD	TCGA;COSMIC	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q9UJM3	ERRFI1	O14757	CHEK1	S251	R244Q	244	Missense	distal	-7	no	15.938	16.196	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	5.604	Up-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q9UJM3	ERRFI1	O14757	CHEK1	S302	S307L	307	Missense	distal	5	no	10.251	10.008	PhosphoSitePlus;EPSD	TCGA;ICGC;COSMIC	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q9UJM3	ERRFI1	O14757	CHEK1	S302	E304A	304	Missense	proximal	2	no	10.251	10.159	PhosphoSitePlus;EPSD	TCGA;ICGC;COSMIC	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q9UJM3	ERRFI1	O14757	CHEK1	S334	P333S	333	Missense	proximal	-1	no	8.988	8.541	EPSD	TCGA;ICGC;COSMIC	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q9UJM3	ERRFI1	O14757	CHEK1	S369	G371E	371	Missense	proximal	2	no	11.718	12.332	EPSD	TCGA;ICGC;COSMIC	5.604	Up-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q9UJM3	ERRFI1	O14757	CHEK1	S369	E370K	370	Missense	proximal	1	no	11.718	11.644	EPSD	TCGA;ICGC;COSMIC	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q9UJM3	ERRFI1	O14757	CHEK1	S369	V376G	376	Missense	distal	7	no	11.718	11.688	EPSD	TCGA;ICGC	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q9BXW9	FANCD2	O14757	CHEK1	S8	R5T	5	Missense	distal	-3	no	8.107	-12.462	EPSD	TCGA;ICGC;COSMIC	5.604	Loss
CAMK_CAMKL_CHK1_CHEK1_ST	Q9BXW9	FANCD2	O14757	CHEK1	S331	N334H	334	Missense	distal	3	no	10.926	10.113	PhosphoSitePlus	TCGA;ICGC;COSMIC	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q9BXW9	FANCD2	O14757	CHEK1	S592	A587T	587	Missense	distal	-5	no	2.526	6.387	EPSD	TCGA;ICGC;COSMIC	5.604	Gain
CAMK_CAMKL_CHK1_CHEK1_ST	Q9BXW9	FANCD2	O14757	CHEK1	S717	V715A	715	Missense	proximal	-2	no	5.613	5.536	EPSD	TCGA;ICGC;COSMIC	5.604	Loss
CAMK_CAMKL_CHK1_CHEK1_ST	Q9BXW9	FANCD2	O14757	CHEK1	S978	L972F	972	Missense	distal	-6	no	5.665	5.914	EPSD	TCGA;ICGC;COSMIC	5.604	Up-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q9BXW9	FANCD2	O14757	CHEK1	S1195	S1195N	1195	Missense	central	0	yes	7.106	0.000	EPSD	TCGA;ICGC;COSMIC	5.604	Loss
CAMK_CAMKL_CHK1_CHEK1_ST	Q9UKM9	RALY	O14757	CHEK1	S106	S106C	106	Missense	central	0	yes	14.696	0.000	EPSD	TCGA;ICGC;COSMIC	5.604	Loss
CAMK_CAMKL_CHK1_CHEK1_ST	Q9UKM9	RALY	O14757	CHEK1	S106	A107V	107	Missense	proximal	1	no	14.696	14.671	EPSD	TCGA;ICGC;COSMIC	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q9UKM9	RALY	O14757	CHEK1	T160	R157C	157	Missense	distal	-3	no	7.506	-0.585	PhosphoSitePlus	TCGA;COSMIC	5.604	Loss
CAMK_CAMKL_CHK1_CHEK1_ST	Q9UKM9	RALY	O14757	CHEK1	S184	E186K	186	Missense	proximal	2	no	6.004	6.046	EPSD	TCGA;COSMIC	5.604	Up-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q12888	TP53BP1	O14757	CHEK1	T1270	E1271K	1271	Missense	proximal	1	no	8.486	8.412	EPSD	TCGA;COSMIC	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q12888	TP53BP1	O14757	CHEK1	S1317	S1311F	1311	Missense	distal	-6	no	11.275	11.548	EPSD	TCGA;COSMIC	5.604	Up-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q12888	TP53BP1	O14757	CHEK1	S1430	S1435P	1435	Missense	distal	5	no	6.504	6.422	EPSD	TCGA;COSMIC	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q14966	ZNF638	O14757	CHEK1	S36	L39F	39	Missense	distal	3	no	9.476	10.099	EPSD	TCGA;ICGC;COSMIC	5.604	Up-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q14966	ZNF638	O14757	CHEK1	S375	N372K	372	Missense	distal	-3	no	2.646	9.189	PhosphoSitePlus	TCGA;ICGC;COSMIC	5.604	Gain
CAMK_CAMKL_CHK1_CHEK1_ST	Q14966	ZNF638	O14757	CHEK1	T409	D415Y	415	Missense	distal	6	no	5.191	6.116	EPSD	TCGA;ICGC;COSMIC	5.604	Gain
CAMK_CAMKL_CHK1_CHEK1_ST	Q14966	ZNF638	O14757	CHEK1	S488	R485Q	485	Missense	distal	-3	no	10.760	3.553	EPSD	TCGA;ICGC;COSMIC;GDSC;CCLE	5.604	Loss
CAMK_CAMKL_CHK1_CHEK1_ST	Q14966	ZNF638	O14757	CHEK1	S488	S488C	488	Missense	central	0	yes	10.760	0.000	EPSD	TCGA;ICGC;COSMIC	5.604	Loss
CAMK_CAMKL_CHK1_CHEK1_ST	Q14966	ZNF638	O14757	CHEK1	S488	P491S	491	Missense	distal	3	no	10.760	10.431	EPSD	TCGA;ICGC;COSMIC	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q14966	ZNF638	O14757	CHEK1	S488	R487H	487	Missense	proximal	-1	no	10.760	10.886	EPSD	TCGA;ICGC	5.604	Up-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q14966	ZNF638	O14757	CHEK1	S490	R497K	497	Missense	distal	7	no	8.142	8.217	EPSD	TCGA;ICGC;COSMIC	5.604	Up-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q14966	ZNF638	O14757	CHEK1	S490	R485Q	485	Missense	distal	-5	no	8.142	7.746	EPSD	TCGA;ICGC;COSMIC;GDSC;CCLE	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q14966	ZNF638	O14757	CHEK1	S490	S488C	488	Missense	proximal	-2	no	8.142	8.190	EPSD	TCGA;ICGC;COSMIC	5.604	Up-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q14966	ZNF638	O14757	CHEK1	S490	P491S	491	Missense	proximal	1	no	8.142	8.179	EPSD	TCGA;ICGC;COSMIC	5.604	Up-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q14966	ZNF638	O14757	CHEK1	S490	R487H	487	Missense	distal	-3	no	8.142	2.333	EPSD	TCGA;ICGC	5.604	Loss
CAMK_CAMKL_CHK1_CHEK1_ST	Q14966	ZNF638	O14757	CHEK1	S500	R497K	497	Missense	distal	-3	no	9.280	5.455	EPSD	TCGA;ICGC;COSMIC	5.604	Loss
CAMK_CAMKL_CHK1_CHEK1_ST	Q14966	ZNF638	O14757	CHEK1	S500	R507L	507	Missense	distal	7	no	9.280	9.180	EPSD	TCGA;ICGC;COSMIC	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q14966	ZNF638	O14757	CHEK1	S500	S502I	502	Missense	proximal	2	no	9.280	8.774	EPSD	TCGA;ICGC;COSMIC	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q14966	ZNF638	O14757	CHEK1	S500	S501L	501	Missense	proximal	1	no	9.280	9.272	EPSD	TCGA;ICGC;COSMIC;GDSC;CCLE	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q14966	ZNF638	O14757	CHEK1	S500	R507Q	507	Missense	distal	7	no	9.280	9.435	EPSD	TCGA;ICGC;COSMIC;CCLE	5.604	Up-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q14966	ZNF638	O14757	CHEK1	S501	R497K	497	Missense	distal	-4	no	9.081	9.182	EPSD	TCGA;ICGC;COSMIC	5.604	Up-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q14966	ZNF638	O14757	CHEK1	S501	R507L	507	Missense	distal	6	no	9.081	9.402	EPSD	TCGA;ICGC;COSMIC	5.604	Up-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q14966	ZNF638	O14757	CHEK1	S501	S502I	502	Missense	proximal	1	no	9.081	9.045	EPSD	TCGA;ICGC;COSMIC	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q14966	ZNF638	O14757	CHEK1	S501	S501L	501	Missense	central	0	yes	9.081	0.000	EPSD	TCGA;ICGC;COSMIC;GDSC;CCLE	5.604	Loss
CAMK_CAMKL_CHK1_CHEK1_ST	Q14966	ZNF638	O14757	CHEK1	S501	R507Q	507	Missense	distal	6	no	9.081	9.074	EPSD	TCGA;ICGC;COSMIC;CCLE	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q14966	ZNF638	O14757	CHEK1	S510	R507L	507	Missense	distal	-3	no	9.474	-9.073	EPSD	TCGA;ICGC;COSMIC	5.604	Loss
CAMK_CAMKL_CHK1_CHEK1_ST	Q14966	ZNF638	O14757	CHEK1	S510	R507Q	507	Missense	distal	-3	no	9.474	2.267	EPSD	TCGA;ICGC;COSMIC;CCLE	5.604	Loss
CAMK_CAMKL_CHK1_CHEK1_ST	Q14966	ZNF638	O14757	CHEK1	S510	R509Q	509	Missense	proximal	-1	no	9.474	9.489	EPSD	TCGA;ICGC;COSMIC	5.604	Up-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q14966	ZNF638	O14757	CHEK1	S520	R524I	524	Missense	distal	4	no	6.328	6.329	EPSD	TCGA;ICGC	5.604	Up-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q14966	ZNF638	O14757	CHEK1	S522	R528H	528	Missense	distal	6	no	7.756	8.044	EPSD	TCGA;ICGC;COSMIC	5.604	Up-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q14966	ZNF638	O14757	CHEK1	S522	R524I	524	Missense	proximal	2	no	7.756	7.345	EPSD	TCGA;ICGC	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q14966	ZNF638	O14757	CHEK1	S537	S537F	537	Missense	central	0	yes	7.789	0.000	EPSD	TCGA;ICGC;COSMIC	5.604	Loss
CAMK_CAMKL_CHK1_CHEK1_ST	Q14966	ZNF638	O14757	CHEK1	S537	R544Q	544	Missense	distal	7	no	7.789	7.944	EPSD	TCGA;ICGC;COSMIC;CCLE	5.604	Up-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q14966	ZNF638	O14757	CHEK1	S537	R540H	540	Missense	distal	3	no	7.789	7.820	EPSD	TCGA;ICGC;COSMIC	5.604	Up-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q14966	ZNF638	O14757	CHEK1	S539	S537F	537	Missense	proximal	-2	no	9.882	10.172	EPSD	TCGA;ICGC;COSMIC	5.604	Up-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q14966	ZNF638	O14757	CHEK1	S539	R544Q	544	Missense	distal	5	no	9.882	9.958	EPSD	TCGA;ICGC;COSMIC;CCLE	5.604	Up-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q14966	ZNF638	O14757	CHEK1	S539	R540H	540	Missense	proximal	1	no	9.882	9.817	EPSD	TCGA;ICGC;COSMIC	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q14966	ZNF638	O14757	CHEK1	S541	S537F	537	Missense	distal	-4	no	7.529	7.287	EPSD	TCGA;ICGC;COSMIC	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q14966	ZNF638	O14757	CHEK1	S541	R544Q	544	Missense	distal	3	no	7.529	8.591	EPSD	TCGA;ICGC;COSMIC;CCLE	5.604	Up-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q14966	ZNF638	O14757	CHEK1	S541	P548L	548	Missense	distal	7	no	7.529	7.466	EPSD	TCGA;ICGC;COSMIC	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q14966	ZNF638	O14757	CHEK1	S541	R540H	540	Missense	proximal	-1	no	7.529	7.655	EPSD	TCGA;ICGC;COSMIC	5.604	Up-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q14966	ZNF638	O14757	CHEK1	S614	S614N	614	Missense	central	0	yes	6.677	0.000	EPSD	TCGA;ICGC;COSMIC	5.604	Loss
CAMK_CAMKL_CHK1_CHEK1_ST	Q14966	ZNF638	O14757	CHEK1	S614	T612I	612	Missense	proximal	-2	no	6.677	6.551	EPSD	TCGA;ICGC;COSMIC	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q14966	ZNF638	O14757	CHEK1	S614	P618S	618	Missense	distal	4	no	6.677	6.537	EPSD	TCGA;ICGC	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q14966	ZNF638	O14757	CHEK1	S614	P618L	618	Missense	distal	4	no	6.677	6.573	EPSD	TCGA;ICGC	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q14966	ZNF638	O14757	CHEK1	S624	A625T	625	Missense	proximal	1	no	5.919	5.909	EPSD	TCGA;ICGC;COSMIC	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q14966	ZNF638	O14757	CHEK1	S624	P618S	618	Missense	distal	-6	no	5.919	5.822	EPSD	TCGA;ICGC	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q14966	ZNF638	O14757	CHEK1	S624	P618L	618	Missense	distal	-6	no	5.919	5.846	EPSD	TCGA;ICGC	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q14966	ZNF638	O14757	CHEK1	S641	C639F	639	Missense	proximal	-2	no	6.761	7.004	EPSD	TCGA;ICGC;COSMIC	5.604	Up-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q14966	ZNF638	O14757	CHEK1	S641	S636C	636	Missense	distal	-5	no	6.761	6.294	EPSD	TCGA;ICGC;COSMIC	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q14966	ZNF638	O14757	CHEK1	S641	L644V	644	Missense	distal	3	no	6.761	7.534	EPSD	TCGA;ICGC;COSMIC	5.604	Up-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q14966	ZNF638	O14757	CHEK1	S641	R638C	638	Missense	distal	-3	no	6.761	-1.330	EPSD	TCGA;ICGC;COSMIC;GDSC;CCLE	5.604	Loss
CAMK_CAMKL_CHK1_CHEK1_ST	Q14966	ZNF638	O14757	CHEK1	S641	T648A	648	Missense	distal	7	no	6.761	6.878	EPSD	TCGA;ICGC	5.604	Up-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q14966	ZNF638	O14757	CHEK1	S661	D657N	657	Missense	distal	-4	no	5.901	5.825	EPSD	TCGA;ICGC;COSMIC	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q14966	ZNF638	O14757	CHEK1	S661	V655L	655	Missense	distal	-6	no	5.901	5.913	EPSD	TCGA;ICGC;COSMIC	5.604	Up-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q14966	ZNF638	O14757	CHEK1	S801	S801Y	801	Missense	central	0	yes	6.110	0.000	EPSD	TCGA;ICGC;COSMIC	5.604	Loss
CAMK_CAMKL_CHK1_CHEK1_ST	Q14966	ZNF638	O14757	CHEK1	S1245	I1251F	1251	Missense	distal	6	no	6.669	7.030	EPSD	TCGA;ICGC;COSMIC	5.604	Up-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q14966	ZNF638	O14757	CHEK1	S1245	L1240I	1240	Missense	distal	-5	no	6.669	4.638	EPSD	TCGA;ICGC;COSMIC	5.604	Loss
CAMK_CAMKL_CHK1_CHEK1_ST	Q14966	ZNF638	O14757	CHEK1	S1444	E1451K	1451	Missense	distal	7	no	6.606	6.441	EPSD	TCGA;ICGC;COSMIC	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q14966	ZNF638	O14757	CHEK1	S1468	G1466R	1466	Missense	proximal	-2	no	9.304	9.270	EPSD	TCGA;ICGC;COSMIC	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q14966	ZNF638	O14757	CHEK1	S1479	D1485H	1485	Missense	distal	6	no	6.658	7.217	EPSD	TCGA;ICGC;COSMIC	5.604	Up-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q14966	ZNF638	O14757	CHEK1	T1487	D1485H	1485	Missense	proximal	-2	no	9.382	9.498	EPSD	TCGA;ICGC;COSMIC	5.604	Up-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q14966	ZNF638	O14757	CHEK1	T1487	S1490Y	1490	Missense	distal	3	no	9.382	8.154	EPSD	TCGA;ICGC;COSMIC	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q14966	ZNF638	O14757	CHEK1	S1823	E1822Q	1822	Missense	proximal	-1	no	6.539	6.644	EPSD	TCGA;ICGC;COSMIC	5.604	Up-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q14966	ZNF638	O14757	CHEK1	T1848	I1843T	1843	Missense	distal	-5	no	8.423	8.399	EPSD	TCGA;ICGC;COSMIC	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q14966	ZNF638	O14757	CHEK1	T1848	K1854N	1854	Missense	distal	6	no	8.423	8.558	EPSD	TCGA;ICGC;COSMIC	5.604	Up-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q14966	ZNF638	O14757	CHEK1	T1853	K1854N	1854	Missense	proximal	1	no	5.828	5.799	EPSD	TCGA;ICGC;COSMIC	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q99590	SCAF11	O14757	CHEK1	T331	R325C	325	Missense	distal	-6	no	8.052	8.168	EPSD	TCGA;ICGC;COSMIC	5.604	Up-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q99590	SCAF11	O14757	CHEK1	T331	R325H	325	Missense	distal	-6	no	8.052	8.162	EPSD	TCGA;ICGC;COSMIC	5.604	Up-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q99590	SCAF11	O14757	CHEK1	S402	E408G	408	Missense	distal	6	no	5.466	5.948	EPSD	TCGA;ICGC;COSMIC	5.604	Gain
CAMK_CAMKL_CHK1_CHEK1_ST	Q99590	SCAF11	O14757	CHEK1	T689	E690K	690	Missense	proximal	1	no	6.485	6.411	EPSD	TCGA;ICGC;COSMIC	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q99590	SCAF11	O14757	CHEK1	S796	R791I	791	Missense	distal	-5	no	7.134	8.080	EPSD	TCGA;ICGC	5.604	Up-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q99590	SCAF11	O14757	CHEK1	S796	R790Q	790	Missense	distal	-6	no	7.134	7.216	EPSD	TCGA;ICGC;GDSC;CCLE	5.604	Up-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q99590	SCAF11	O14757	CHEK1	S816	P817S	817	Missense	proximal	1	no	9.655	9.692	EPSD	TCGA;ICGC;COSMIC	5.604	Up-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q99590	SCAF11	O14757	CHEK1	T823	P817S	817	Missense	distal	-6	no	9.084	8.987	EPSD	TCGA;ICGC;COSMIC	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q99590	SCAF11	O14757	CHEK1	T823	K825E	825	Missense	proximal	2	no	9.084	9.043	EPSD	TCGA;ICGC;COSMIC	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q99590	SCAF11	O14757	CHEK1	S832	Q831P	831	Missense	proximal	-1	no	5.434	5.704	EPSD	TCGA;ICGC;COSMIC	5.604	Gain
CAMK_CAMKL_CHK1_CHEK1_ST	Q99590	SCAF11	O14757	CHEK1	S839	G842D	842	Missense	distal	3	no	4.463	6.108	EPSD	TCGA;ICGC	5.604	Gain
CAMK_CAMKL_CHK1_CHEK1_ST	Q99590	SCAF11	O14757	CHEK1	S846	G842D	842	Missense	distal	-4	no	7.652	7.688	EPSD	TCGA;ICGC	5.604	Up-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q99590	SCAF11	O14757	CHEK1	S862	R865Q	865	Missense	distal	3	no	4.598	5.660	EPSD	TCGA;ICGC;COSMIC	5.604	Gain
CAMK_CAMKL_CHK1_CHEK1_ST	Q99590	SCAF11	O14757	CHEK1	S880	R877I	877	Missense	distal	-3	no	8.233	-0.525	EPSD	TCGA;ICGC;COSMIC	5.604	Loss
CAMK_CAMKL_CHK1_CHEK1_ST	Q99590	SCAF11	O14757	CHEK1	S902	P903L	903	Missense	proximal	1	no	7.337	7.364	EPSD	TCGA;ICGC;COSMIC	5.604	Up-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q99590	SCAF11	O14757	CHEK1	S902	S907F	907	Missense	distal	5	no	7.337	7.012	EPSD	TCGA;ICGC;COSMIC	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q99590	SCAF11	O14757	CHEK1	S902	G904V	904	Missense	proximal	2	no	7.337	7.295	EPSD	TCGA;ICGC;COSMIC	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q99590	SCAF11	O14757	CHEK1	S911	S907F	907	Missense	distal	-4	no	10.838	10.596	EPSD	TCGA;ICGC;COSMIC	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q99590	SCAF11	O14757	CHEK1	S911	G904V	904	Missense	distal	-7	no	10.838	10.853	EPSD	TCGA;ICGC;COSMIC	5.604	Up-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q99590	SCAF11	O14757	CHEK1	S911	S911I	911	Missense	central	0	yes	10.838	0.000	EPSD	TCGA;ICGC	5.604	Loss
CAMK_CAMKL_CHK1_CHEK1_ST	Q99590	SCAF11	O14757	CHEK1	S937	R930K	930	Missense	distal	-7	no	8.093	9.273	EPSD	TCGA;ICGC;COSMIC	5.604	Up-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q99590	SCAF11	O14757	CHEK1	S937	S935Y	935	Missense	proximal	-2	no	8.093	8.206	EPSD	TCGA;ICGC;COSMIC	5.604	Up-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q99590	SCAF11	O14757	CHEK1	S937	R944I	944	Missense	distal	7	no	8.093	7.709	EPSD	TCGA;ICGC	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q99590	SCAF11	O14757	CHEK1	S939	S935Y	935	Missense	distal	-4	no	7.553	7.376	EPSD	TCGA;ICGC;COSMIC	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q99590	SCAF11	O14757	CHEK1	S939	R944I	944	Missense	distal	5	no	7.553	7.513	EPSD	TCGA;ICGC	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q99590	SCAF11	O14757	CHEK1	S943	R944I	944	Missense	proximal	1	no	6.778	6.717	EPSD	TCGA;ICGC	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q99590	SCAF11	O14757	CHEK1	S951	S953P	953	Missense	proximal	2	no	8.936	8.859	EPSD	TCGA;COSMIC	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q99590	SCAF11	O14757	CHEK1	S951	R944I	944	Missense	distal	-7	no	8.936	8.553	EPSD	TCGA;ICGC	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q99590	SCAF11	O14757	CHEK1	S953	S953P	953	Missense	central	0	yes	8.300	0.000	EPSD	TCGA;COSMIC	5.604	Loss
CAMK_CAMKL_CHK1_CHEK1_ST	Q99590	SCAF11	O14757	CHEK1	S1030	K1027Q	1027	Missense	distal	-3	no	8.788	5.406	EPSD	TCGA;COSMIC	5.604	Loss
CAMK_CAMKL_CHK1_CHEK1_ST	Q99590	SCAF11	O14757	CHEK1	S1104	R1100Q	1100	Missense	distal	-4	no	6.104	6.264	EPSD	TCGA;ICGC	5.604	Up-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q99590	SCAF11	O14757	CHEK1	S1127	E1130Q	1130	Missense	distal	3	no	7.093	6.692	PhosphoSitePlus	TCGA;ICGC;COSMIC	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q99590	SCAF11	O14757	CHEK1	S1127	S1132L	1132	Missense	distal	5	no	7.093	6.849	PhosphoSitePlus	TCGA;ICGC;COSMIC	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q99590	SCAF11	O14757	CHEK1	S1127	R1125Q	1125	Missense	proximal	-2	no	7.093	7.139	PhosphoSitePlus	TCGA;ICGC	5.604	Up-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q99590	SCAF11	O14757	CHEK1	S1188	G1185E	1185	Missense	distal	-3	no	5.102	5.788	EPSD	TCGA;ICGC	5.604	Gain
CAMK_CAMKL_CHK1_CHEK1_ST	Q99590	SCAF11	O14757	CHEK1	S1189	N1195S	1195	Missense	distal	6	no	7.193	7.058	EPSD	TCGA;ICGC;COSMIC	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q99590	SCAF11	O14757	CHEK1	S1189	G1185E	1185	Missense	distal	-4	no	7.193	7.370	EPSD	TCGA;ICGC	5.604	Up-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q99590	SCAF11	O14757	CHEK1	S1361	S1358R	1358	Missense	distal	-3	no	-3.697	5.998	EPSD	TCGA;ICGC;COSMIC	5.604	Gain
CAMK_CAMKL_CHK1_CHEK1_ST	Q9UQ35	SRRM2	O14757	CHEK1	S24	G28C	28	Missense	distal	4	no	11.692	11.779	EPSD	TCGA;ICGC;COSMIC	5.604	Up-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q9UQ35	SRRM2	O14757	CHEK1	T111	G107A	107	Missense	distal	-4	no	6.570	6.615	EPSD	TCGA;ICGC;COSMIC	5.604	Up-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q9UQ35	SRRM2	O14757	CHEK1	T111	Q114H	114	Missense	distal	3	no	6.570	5.538	EPSD	TCGA;ICGC;COSMIC;GDSC;CCLE	5.604	Loss
CAMK_CAMKL_CHK1_CHEK1_ST	Q9UQ35	SRRM2	O14757	CHEK1	S178	S177C	177	Missense	proximal	-1	no	10.891	11.087	EPSD	TCGA;ICGC;COSMIC	5.604	Up-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q9UQ35	SRRM2	O14757	CHEK1	S178	R175W	175	Missense	distal	-3	no	10.891	-22.712	EPSD	TCGA;ICGC;COSMIC	5.604	Loss
CAMK_CAMKL_CHK1_CHEK1_ST	Q9UQ35	SRRM2	O14757	CHEK1	S178	S179R	179	Missense	proximal	1	no	10.891	10.917	EPSD	TCGA;ICGC;COSMIC	5.604	Up-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q9UQ35	SRRM2	O14757	CHEK1	S178	R181H	181	Missense	distal	3	no	10.891	10.922	EPSD	TCGA;ICGC;COSMIC	5.604	Up-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q9UQ35	SRRM2	O14757	CHEK1	S182	S179R	179	Missense	distal	-3	no	-0.927	8.769	EPSD	TCGA;ICGC;COSMIC	5.604	Gain
CAMK_CAMKL_CHK1_CHEK1_ST	Q9UQ35	SRRM2	O14757	CHEK1	T184	S177C	177	Missense	distal	-7	no	10.108	9.120	EPSD	TCGA;ICGC;COSMIC	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q9UQ35	SRRM2	O14757	CHEK1	T184	S179R	179	Missense	distal	-5	no	10.108	10.319	EPSD	TCGA;ICGC;COSMIC	5.604	Up-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q9UQ35	SRRM2	O14757	CHEK1	T184	R181H	181	Missense	distal	-3	no	10.108	4.298	EPSD	TCGA;ICGC;COSMIC	5.604	Loss
CAMK_CAMKL_CHK1_CHEK1_ST	Q9UQ35	SRRM2	O14757	CHEK1	S202	E201K	201	Missense	proximal	-1	no	6.308	6.250	EPSD	TCGA;ICGC;COSMIC	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q9UQ35	SRRM2	O14757	CHEK1	S202	D195H	195	Missense	distal	-7	no	6.308	6.219	EPSD	TCGA;ICGC;COSMIC	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q9UQ35	SRRM2	O14757	CHEK1	S202	P205L	205	Missense	distal	3	no	6.308	5.544	EPSD	TCGA;ICGC;COSMIC	5.604	Loss
CAMK_CAMKL_CHK1_CHEK1_ST	Q9UQ35	SRRM2	O14757	CHEK1	S202	R199M	199	Missense	distal	-3	no	6.308	1.159	EPSD	TCGA;ICGC;COSMIC	5.604	Loss
CAMK_CAMKL_CHK1_CHEK1_ST	Q9UQ35	SRRM2	O14757	CHEK1	S202	R198C	198	Missense	distal	-4	no	6.308	5.934	EPSD	TCGA;ICGC;COSMIC	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q9UQ35	SRRM2	O14757	CHEK1	S212	P205L	205	Missense	distal	-7	no	6.451	6.236	EPSD	TCGA;ICGC;COSMIC	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q9UQ35	SRRM2	O14757	CHEK1	S212	S212G	212	Missense	central	0	yes	6.451	0.000	EPSD	TCGA;ICGC;COSMIC	5.604	Loss
CAMK_CAMKL_CHK1_CHEK1_ST	Q9UQ35	SRRM2	O14757	CHEK1	T233	P232S	232	Missense	proximal	-1	no	8.336	7.889	EPSD	TCGA;ICGC	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q9UQ35	SRRM2	O14757	CHEK1	T233	S231F	231	Missense	proximal	-2	no	8.336	8.626	EPSD	TCGA;ICGC;COSMIC	5.604	Up-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q9UQ35	SRRM2	O14757	CHEK1	S248	R245Q	245	Missense	distal	-3	no	10.348	3.141	EPSD	TCGA;ICGC;COSMIC	5.604	Loss
CAMK_CAMKL_CHK1_CHEK1_ST	Q9UQ35	SRRM2	O14757	CHEK1	S248	P255L	255	Missense	distal	7	no	10.348	10.285	EPSD	TCGA;ICGC;COSMIC	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q9UQ35	SRRM2	O14757	CHEK1	S248	R249Q	249	Missense	proximal	1	no	10.348	10.357	EPSD	TCGA;ICGC;COSMIC	5.604	Up-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q9UQ35	SRRM2	O14757	CHEK1	S250	R245Q	245	Missense	distal	-5	no	7.002	6.606	EPSD	TCGA;ICGC;COSMIC	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q9UQ35	SRRM2	O14757	CHEK1	S250	P255L	255	Missense	distal	5	no	7.002	6.840	EPSD	TCGA;ICGC;COSMIC	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q9UQ35	SRRM2	O14757	CHEK1	S250	R249Q	249	Missense	proximal	-1	no	7.002	7.017	EPSD	TCGA;ICGC;COSMIC	5.604	Up-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q9UQ35	SRRM2	O14757	CHEK1	T252	R245Q	245	Missense	distal	-7	no	7.267	7.525	EPSD	TCGA;ICGC;COSMIC	5.604	Up-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q9UQ35	SRRM2	O14757	CHEK1	T252	P255L	255	Missense	distal	3	no	7.267	6.504	EPSD	TCGA;ICGC;COSMIC	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q9UQ35	SRRM2	O14757	CHEK1	T252	R249Q	249	Missense	distal	-3	no	7.267	0.060	EPSD	TCGA;ICGC;COSMIC	5.604	Loss
CAMK_CAMKL_CHK1_CHEK1_ST	Q9UQ35	SRRM2	O14757	CHEK1	S297	R303H	303	Missense	distal	6	no	8.855	9.142	EPSD	TCGA;ICGC;COSMIC	5.604	Up-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q9UQ35	SRRM2	O14757	CHEK1	S297	G304R	304	Missense	distal	7	no	8.855	8.849	EPSD	TCGA;ICGC;COSMIC	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q9UQ35	SRRM2	O14757	CHEK1	S323	R320Q	320	Missense	distal	-3	no	9.116	1.909	EPSD	TCGA;ICGC	5.604	Loss
CAMK_CAMKL_CHK1_CHEK1_ST	Q9UQ35	SRRM2	O14757	CHEK1	T348	K343T	343	Missense	distal	-5	no	5.816	5.561	EPSD	TCGA;ICGC;COSMIC	5.604	Loss
CAMK_CAMKL_CHK1_CHEK1_ST	Q9UQ35	SRRM2	O14757	CHEK1	S474	T476A	476	Missense	proximal	2	no	4.920	5.768	EPSD	TCGA;ICGC;COSMIC	5.604	Gain
CAMK_CAMKL_CHK1_CHEK1_ST	Q9UQ35	SRRM2	O14757	CHEK1	S486	G482V	482	Missense	distal	-4	no	6.013	5.979	EPSD	TCGA;ICGC;COSMIC	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q9UQ35	SRRM2	O14757	CHEK1	S486	S486G	486	Missense	central	0	yes	6.013	0.000	EPSD	TCGA;ICGC;COSMIC	5.604	Loss
CAMK_CAMKL_CHK1_CHEK1_ST	Q9UQ35	SRRM2	O14757	CHEK1	S486	R483K	483	Missense	distal	-3	no	6.013	2.187	EPSD	TCGA;ICGC;COSMIC	5.604	Loss
CAMK_CAMKL_CHK1_CHEK1_ST	Q9UQ35	SRRM2	O14757	CHEK1	S495	R494Q	494	Missense	proximal	-1	no	6.706	6.721	EPSD	TCGA;ICGC;COSMIC	5.604	Up-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q9UQ35	SRRM2	O14757	CHEK1	S495	P500S	500	Missense	distal	5	no	6.706	6.788	EPSD	TCGA;ICGC;COSMIC	5.604	Up-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q9UQ35	SRRM2	O14757	CHEK1	S497	R494Q	494	Missense	distal	-3	no	11.538	4.331	EPSD	TCGA;ICGC;COSMIC	5.604	Loss
CAMK_CAMKL_CHK1_CHEK1_ST	Q9UQ35	SRRM2	O14757	CHEK1	S497	P500S	500	Missense	distal	3	no	11.538	11.208	EPSD	TCGA;ICGC;COSMIC	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q9UQ35	SRRM2	O14757	CHEK1	T499	R494Q	494	Missense	distal	-5	no	8.894	8.498	EPSD	TCGA;ICGC;COSMIC	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q9UQ35	SRRM2	O14757	CHEK1	T499	S506Y	506	Missense	distal	7	no	8.894	8.379	EPSD	TCGA;COSMIC	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q9UQ35	SRRM2	O14757	CHEK1	T499	P500S	500	Missense	proximal	1	no	8.894	8.930	EPSD	TCGA;ICGC;COSMIC	5.604	Up-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q9UQ35	SRRM2	O14757	CHEK1	T501	R494Q	494	Missense	distal	-7	no	10.444	10.702	EPSD	TCGA;ICGC;COSMIC	5.604	Up-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q9UQ35	SRRM2	O14757	CHEK1	T501	S506Y	506	Missense	distal	5	no	10.444	9.990	EPSD	TCGA;COSMIC	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q9UQ35	SRRM2	O14757	CHEK1	T501	S508F	508	Missense	distal	7	no	10.444	10.014	EPSD	TCGA;ICGC;COSMIC	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q9UQ35	SRRM2	O14757	CHEK1	T501	P500S	500	Missense	proximal	-1	no	10.444	9.997	EPSD	TCGA;ICGC;COSMIC	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q9UQ35	SRRM2	O14757	CHEK1	S506	S506Y	506	Missense	central	0	yes	10.490	0.000	EPSD	TCGA;COSMIC	5.604	Loss
CAMK_CAMKL_CHK1_CHEK1_ST	Q9UQ35	SRRM2	O14757	CHEK1	S506	S508F	508	Missense	proximal	2	no	10.490	10.346	EPSD	TCGA;ICGC;COSMIC	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q9UQ35	SRRM2	O14757	CHEK1	S506	P500S	500	Missense	distal	-6	no	10.490	10.393	EPSD	TCGA;ICGC;COSMIC	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q9UQ35	SRRM2	O14757	CHEK1	S510	S506Y	506	Missense	distal	-4	no	8.007	7.830	EPSD	TCGA;COSMIC	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q9UQ35	SRRM2	O14757	CHEK1	S510	R514C	514	Missense	distal	4	no	8.007	8.110	EPSD	TCGA;ICGC;COSMIC	5.604	Up-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q9UQ35	SRRM2	O14757	CHEK1	S510	S508F	508	Missense	proximal	-2	no	8.007	8.296	EPSD	TCGA;ICGC;COSMIC	5.604	Up-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q9UQ35	SRRM2	O14757	CHEK1	S518	W522C	522	Missense	distal	4	no	9.935	9.976	EPSD	TCGA	5.604	Up-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q9UQ35	SRRM2	O14757	CHEK1	S518	R514C	514	Missense	distal	-4	no	9.935	9.561	EPSD	TCGA;ICGC;COSMIC	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q9UQ35	SRRM2	O14757	CHEK1	S518	R524T	524	Missense	distal	6	no	9.935	10.158	EPSD	TCGA;ICGC;COSMIC	5.604	Up-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q9UQ35	SRRM2	O14757	CHEK1	S527	W522C	522	Missense	distal	-5	no	10.142	10.323	EPSD	TCGA	5.604	Up-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q9UQ35	SRRM2	O14757	CHEK1	S527	Q529H	529	Missense	proximal	2	no	10.142	9.632	EPSD	TCGA;ICGC	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q9UQ35	SRRM2	O14757	CHEK1	S527	R524T	524	Missense	distal	-3	no	10.142	-10.427	EPSD	TCGA;ICGC;COSMIC	5.604	Loss
CAMK_CAMKL_CHK1_CHEK1_ST	Q9UQ35	SRRM2	O14757	CHEK1	S527	R531H	531	Missense	distal	4	no	10.142	10.303	EPSD	TCGA;ICGC;COSMIC	5.604	Up-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q9UQ35	SRRM2	O14757	CHEK1	S534	S536F	536	Missense	proximal	2	no	10.389	10.245	EPSD	TCGA;ICGC;COSMIC	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q9UQ35	SRRM2	O14757	CHEK1	S534	Q529H	529	Missense	distal	-5	no	10.389	8.320	EPSD	TCGA;ICGC	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q9UQ35	SRRM2	O14757	CHEK1	S534	R531H	531	Missense	distal	-3	no	10.389	4.580	EPSD	TCGA;ICGC;COSMIC	5.604	Loss
CAMK_CAMKL_CHK1_CHEK1_ST	Q9UQ35	SRRM2	O14757	CHEK1	S536	S536F	536	Missense	central	0	yes	10.394	0.000	EPSD	TCGA;ICGC;COSMIC	5.604	Loss
CAMK_CAMKL_CHK1_CHEK1_ST	Q9UQ35	SRRM2	O14757	CHEK1	S536	Q529H	529	Missense	distal	-7	no	10.394	10.077	EPSD	TCGA;ICGC	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q9UQ35	SRRM2	O14757	CHEK1	S536	R531H	531	Missense	distal	-5	no	10.394	7.929	EPSD	TCGA;ICGC;COSMIC	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q9UQ35	SRRM2	O14757	CHEK1	S543	R546T	546	Missense	distal	3	no	5.717	5.577	EPSD	TCGA;ICGC;COSMIC	5.604	Loss
CAMK_CAMKL_CHK1_CHEK1_ST	Q9UQ35	SRRM2	O14757	CHEK1	S543	S536F	536	Missense	distal	-7	no	5.717	3.985	EPSD	TCGA;ICGC;COSMIC	5.604	Loss
CAMK_CAMKL_CHK1_CHEK1_ST	Q9UQ35	SRRM2	O14757	CHEK1	S562	S564C	564	Missense	proximal	2	no	7.793	7.432	EPSD	TCGA;ICGC;COSMIC	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q9UQ35	SRRM2	O14757	CHEK1	S562	H563Y	563	Missense	proximal	1	no	7.793	7.815	EPSD	TCGA;ICGC;COSMIC	5.604	Up-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q9UQ35	SRRM2	O14757	CHEK1	S564	S564C	564	Missense	central	0	yes	10.230	0.000	EPSD	TCGA;ICGC;COSMIC	5.604	Loss
CAMK_CAMKL_CHK1_CHEK1_ST	Q9UQ35	SRRM2	O14757	CHEK1	S564	H563Y	563	Missense	proximal	-1	no	10.230	10.272	EPSD	TCGA;ICGC;COSMIC	5.604	Up-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q9UQ35	SRRM2	O14757	CHEK1	S573	R580C	580	Missense	distal	7	no	7.570	7.165	EPSD	TCGA;ICGC;CCLE	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q9UQ35	SRRM2	O14757	CHEK1	S575	R580C	580	Missense	distal	5	no	11.312	11.068	EPSD	TCGA;ICGC;CCLE	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q9UQ35	SRRM2	O14757	CHEK1	T577	R580C	580	Missense	distal	3	no	10.330	9.383	EPSD	TCGA;ICGC;CCLE	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q9UQ35	SRRM2	O14757	CHEK1	S584	R580C	580	Missense	distal	-4	no	7.028	6.654	EPSD	TCGA;ICGC;CCLE	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q9UQ35	SRRM2	O14757	CHEK1	S584	R591K	591	Missense	distal	7	no	7.028	7.103	EPSD	TCGA;ICGC;COSMIC	5.604	Up-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q9UQ35	SRRM2	O14757	CHEK1	S584	T588I	588	Missense	distal	4	no	7.028	7.068	EPSD	TCGA;ICGC;COSMIC	5.604	Up-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q9UQ35	SRRM2	O14757	CHEK1	S584	A590D	590	Missense	distal	6	no	7.028	6.456	EPSD	TCGA;ICGC	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q9UQ35	SRRM2	O14757	CHEK1	S586	R580C	580	Missense	distal	-6	no	9.434	9.549	EPSD	TCGA;ICGC;CCLE	5.604	Up-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q9UQ35	SRRM2	O14757	CHEK1	S586	R591K	591	Missense	distal	5	no	9.434	9.557	EPSD	TCGA;ICGC;COSMIC	5.604	Up-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q9UQ35	SRRM2	O14757	CHEK1	S586	R592Q	592	Missense	distal	6	no	9.434	9.427	EPSD	TCGA;ICGC;COSMIC	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q9UQ35	SRRM2	O14757	CHEK1	S586	T588I	588	Missense	proximal	2	no	9.434	9.319	EPSD	TCGA;ICGC;COSMIC	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q9UQ35	SRRM2	O14757	CHEK1	S586	R592W	592	Missense	distal	6	no	9.434	9.900	EPSD	TCGA;ICGC;COSMIC	5.604	Up-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q9UQ35	SRRM2	O14757	CHEK1	S586	A590D	590	Missense	distal	4	no	9.434	9.291	EPSD	TCGA;ICGC	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q9UQ35	SRRM2	O14757	CHEK1	T588	R591K	591	Missense	distal	3	no	9.565	10.212	EPSD	TCGA;ICGC;COSMIC	5.604	Up-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q9UQ35	SRRM2	O14757	CHEK1	T588	S594L	594	Missense	distal	6	no	9.565	9.975	EPSD	TCGA;ICGC;COSMIC	5.604	Up-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q9UQ35	SRRM2	O14757	CHEK1	T588	T588I	588	Missense	central	0	yes	9.565	0.000	EPSD	TCGA;ICGC;COSMIC	5.604	Loss
CAMK_CAMKL_CHK1_CHEK1_ST	Q9UQ35	SRRM2	O14757	CHEK1	T588	R592W	592	Missense	distal	4	no	9.565	9.628	EPSD	TCGA;ICGC;COSMIC	5.604	Up-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q9UQ35	SRRM2	O14757	CHEK1	T588	A590D	590	Missense	proximal	2	no	9.565	9.575	EPSD	TCGA;ICGC	5.604	Up-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q9UQ35	SRRM2	O14757	CHEK1	S594	R601S	601	Missense	distal	7	no	8.725	8.632	EPSD	TCGA;ICGC;COSMIC	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q9UQ35	SRRM2	O14757	CHEK1	S594	R591K	591	Missense	distal	-3	no	8.725	4.899	EPSD	TCGA;ICGC;COSMIC	5.604	Loss
CAMK_CAMKL_CHK1_CHEK1_ST	Q9UQ35	SRRM2	O14757	CHEK1	S594	S594L	594	Missense	central	0	yes	8.725	0.000	EPSD	TCGA;ICGC;COSMIC	5.604	Loss
CAMK_CAMKL_CHK1_CHEK1_ST	Q9UQ35	SRRM2	O14757	CHEK1	S594	R592Q	592	Missense	proximal	-2	no	8.725	8.771	EPSD	TCGA;ICGC;COSMIC	5.604	Up-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q9UQ35	SRRM2	O14757	CHEK1	S594	T588I	588	Missense	distal	-6	no	8.725	8.654	EPSD	TCGA;ICGC;COSMIC	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q9UQ35	SRRM2	O14757	CHEK1	S594	R592W	592	Missense	proximal	-2	no	8.725	8.846	EPSD	TCGA;ICGC;COSMIC	5.604	Up-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q9UQ35	SRRM2	O14757	CHEK1	S594	A590D	590	Missense	distal	-4	no	8.725	8.716	EPSD	TCGA;ICGC	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q9UQ35	SRRM2	O14757	CHEK1	S594	R597G	597	Missense	distal	3	no	8.725	8.640	EPSD	TCGA	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q9UQ35	SRRM2	O14757	CHEK1	S596	R602C	602	Missense	distal	6	no	9.124	9.418	EPSD	TCGA;ICGC;COSMIC	5.604	Up-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q9UQ35	SRRM2	O14757	CHEK1	S596	R601S	601	Missense	distal	5	no	9.124	9.227	EPSD	TCGA;ICGC;COSMIC	5.604	Up-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q9UQ35	SRRM2	O14757	CHEK1	S596	R591K	591	Missense	distal	-5	no	9.124	10.300	EPSD	TCGA;ICGC;COSMIC	5.604	Up-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q9UQ35	SRRM2	O14757	CHEK1	S596	S594L	594	Missense	proximal	-2	no	9.124	9.229	EPSD	TCGA;ICGC;COSMIC	5.604	Up-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q9UQ35	SRRM2	O14757	CHEK1	S596	R592Q	592	Missense	distal	-4	no	9.124	9.284	EPSD	TCGA;ICGC;COSMIC	5.604	Up-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q9UQ35	SRRM2	O14757	CHEK1	S596	R592W	592	Missense	distal	-4	no	9.124	8.362	EPSD	TCGA;ICGC;COSMIC	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q9UQ35	SRRM2	O14757	CHEK1	S596	R603K	603	Missense	distal	7	no	9.124	9.199	EPSD	TCGA;ICGC	5.604	Up-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q9UQ35	SRRM2	O14757	CHEK1	S596	A590D	590	Missense	distal	-6	no	9.124	9.078	EPSD	TCGA;ICGC	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q9UQ35	SRRM2	O14757	CHEK1	S596	R597G	597	Missense	proximal	1	no	9.124	9.115	EPSD	TCGA	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q9UQ35	SRRM2	O14757	CHEK1	T598	R602C	602	Missense	distal	4	no	9.349	9.453	EPSD	TCGA;ICGC;COSMIC	5.604	Up-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q9UQ35	SRRM2	O14757	CHEK1	T598	R601S	601	Missense	distal	3	no	9.349	9.352	EPSD	TCGA;ICGC;COSMIC	5.604	Up-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q9UQ35	SRRM2	O14757	CHEK1	T598	R591K	591	Missense	distal	-7	no	9.349	10.529	EPSD	TCGA;ICGC;COSMIC	5.604	Up-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q9UQ35	SRRM2	O14757	CHEK1	T598	R605W	605	Missense	distal	7	no	9.349	8.848	EPSD	TCGA;ICGC;COSMIC;CCLE	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q9UQ35	SRRM2	O14757	CHEK1	T598	S594L	594	Missense	distal	-4	no	9.349	9.402	EPSD	TCGA;ICGC;COSMIC	5.604	Up-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q9UQ35	SRRM2	O14757	CHEK1	T598	R592Q	592	Missense	distal	-6	no	9.349	9.431	EPSD	TCGA;ICGC;COSMIC	5.604	Up-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q9UQ35	SRRM2	O14757	CHEK1	T598	R592W	592	Missense	distal	-6	no	9.349	9.669	EPSD	TCGA;ICGC;COSMIC	5.604	Up-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q9UQ35	SRRM2	O14757	CHEK1	T598	R603K	603	Missense	distal	5	no	9.349	9.473	EPSD	TCGA;ICGC	5.604	Up-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q9UQ35	SRRM2	O14757	CHEK1	T598	R597G	597	Missense	proximal	-1	no	9.349	9.367	EPSD	TCGA	5.604	Up-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q9UQ35	SRRM2	O14757	CHEK1	T600	R602C	602	Missense	proximal	2	no	10.532	10.266	EPSD	TCGA;ICGC;COSMIC	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q9UQ35	SRRM2	O14757	CHEK1	T600	R601S	601	Missense	proximal	1	no	10.532	10.506	EPSD	TCGA;ICGC;COSMIC	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q9UQ35	SRRM2	O14757	CHEK1	T600	R605W	605	Missense	distal	5	no	10.532	10.364	EPSD	TCGA;ICGC;COSMIC;CCLE	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q9UQ35	SRRM2	O14757	CHEK1	T600	S594L	594	Missense	distal	-6	no	10.532	10.557	EPSD	TCGA;ICGC;COSMIC	5.604	Up-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q9UQ35	SRRM2	O14757	CHEK1	T600	R603K	603	Missense	distal	3	no	10.532	11.179	EPSD	TCGA;ICGC	5.604	Up-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q9UQ35	SRRM2	O14757	CHEK1	T600	R597G	597	Missense	distal	-3	no	10.532	2.758	EPSD	TCGA	5.604	Loss
CAMK_CAMKL_CHK1_CHEK1_ST	Q9UQ35	SRRM2	O14757	CHEK1	S604	R602C	602	Missense	proximal	-2	no	9.233	9.181	EPSD	TCGA;ICGC;COSMIC	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q9UQ35	SRRM2	O14757	CHEK1	S604	R601S	601	Missense	distal	-3	no	9.233	-0.463	EPSD	TCGA;ICGC;COSMIC	5.604	Loss
CAMK_CAMKL_CHK1_CHEK1_ST	Q9UQ35	SRRM2	O14757	CHEK1	S604	R605W	605	Missense	proximal	1	no	9.233	9.203	EPSD	TCGA;ICGC;COSMIC;CCLE	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q9UQ35	SRRM2	O14757	CHEK1	S604	R603K	603	Missense	proximal	-1	no	9.233	9.085	EPSD	TCGA;ICGC	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q9UQ35	SRRM2	O14757	CHEK1	S604	R597G	597	Missense	distal	-7	no	9.233	9.271	EPSD	TCGA	5.604	Up-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q9UQ35	SRRM2	O14757	CHEK1	S606	R602C	602	Missense	distal	-4	no	11.265	10.891	EPSD	TCGA;ICGC;COSMIC	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q9UQ35	SRRM2	O14757	CHEK1	S606	R601S	601	Missense	distal	-5	no	11.265	11.054	EPSD	TCGA;ICGC;COSMIC	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q9UQ35	SRRM2	O14757	CHEK1	S606	R605W	605	Missense	proximal	-1	no	11.265	11.383	EPSD	TCGA;ICGC;COSMIC;CCLE	5.604	Up-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q9UQ35	SRRM2	O14757	CHEK1	S606	R603K	603	Missense	distal	-3	no	11.265	7.440	EPSD	TCGA;ICGC	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q9UQ35	SRRM2	O14757	CHEK1	T608	R602C	602	Missense	distal	-6	no	8.834	8.950	EPSD	TCGA;ICGC;COSMIC	5.604	Up-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q9UQ35	SRRM2	O14757	CHEK1	T608	S615F	615	Missense	distal	7	no	8.834	8.404	EPSD	TCGA	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q9UQ35	SRRM2	O14757	CHEK1	T608	R601S	601	Missense	distal	-7	no	8.834	9.093	EPSD	TCGA;ICGC;COSMIC	5.604	Up-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q9UQ35	SRRM2	O14757	CHEK1	T608	R605W	605	Missense	distal	-3	no	8.834	-24.769	EPSD	TCGA;ICGC;COSMIC;CCLE	5.604	Loss
CAMK_CAMKL_CHK1_CHEK1_ST	Q9UQ35	SRRM2	O14757	CHEK1	T608	R603K	603	Missense	distal	-5	no	8.834	10.010	EPSD	TCGA;ICGC	5.604	Up-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q9UQ35	SRRM2	O14757	CHEK1	S615	S615F	615	Missense	central	0	yes	8.413	0.000	EPSD	TCGA	5.604	Loss
CAMK_CAMKL_CHK1_CHEK1_ST	Q9UQ35	SRRM2	O14757	CHEK1	S615	S617C	617	Missense	proximal	2	no	8.413	8.052	EPSD	TCGA	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q9UQ35	SRRM2	O14757	CHEK1	S615	R622S	622	Missense	distal	7	no	8.413	8.320	EPSD	TCGA;ICGC;COSMIC	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q9UQ35	SRRM2	O14757	CHEK1	S617	S615F	615	Missense	proximal	-2	no	10.600	10.890	EPSD	TCGA	5.604	Up-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q9UQ35	SRRM2	O14757	CHEK1	S617	S617C	617	Missense	central	0	yes	10.600	0.000	EPSD	TCGA	5.604	Loss
CAMK_CAMKL_CHK1_CHEK1_ST	Q9UQ35	SRRM2	O14757	CHEK1	S617	R622S	622	Missense	distal	5	no	10.600	10.703	EPSD	TCGA;ICGC;COSMIC	5.604	Up-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q9UQ35	SRRM2	O14757	CHEK1	S617	R623H	623	Missense	distal	6	no	10.600	10.888	EPSD	TCGA;ICGC	5.604	Up-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q9UQ35	SRRM2	O14757	CHEK1	T619	S615F	615	Missense	distal	-4	no	9.168	8.926	EPSD	TCGA	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q9UQ35	SRRM2	O14757	CHEK1	T619	S617C	617	Missense	proximal	-2	no	9.168	9.216	EPSD	TCGA	5.604	Up-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q9UQ35	SRRM2	O14757	CHEK1	T619	R622S	622	Missense	distal	3	no	9.168	9.171	EPSD	TCGA;ICGC;COSMIC	5.604	Up-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q9UQ35	SRRM2	O14757	CHEK1	T619	R623H	623	Missense	distal	4	no	9.168	9.329	EPSD	TCGA;ICGC	5.604	Up-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q9UQ35	SRRM2	O14757	CHEK1	S625	R622S	622	Missense	distal	-3	no	10.749	1.053	EPSD	TCGA;ICGC;COSMIC	5.604	Loss
CAMK_CAMKL_CHK1_CHEK1_ST	Q9UQ35	SRRM2	O14757	CHEK1	S625	R632Q	632	Missense	distal	7	no	10.749	10.904	EPSD	TCGA;ICGC;COSMIC	5.604	Up-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q9UQ35	SRRM2	O14757	CHEK1	S625	R623H	623	Missense	proximal	-2	no	10.749	10.814	EPSD	TCGA;ICGC	5.604	Up-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q9UQ35	SRRM2	O14757	CHEK1	T627	R634S	634	Missense	distal	7	no	8.793	8.701	EPSD	TCGA;ICGC;COSMIC	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q9UQ35	SRRM2	O14757	CHEK1	T627	R622S	622	Missense	distal	-5	no	8.793	8.582	EPSD	TCGA;ICGC;COSMIC	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q9UQ35	SRRM2	O14757	CHEK1	T627	R632Q	632	Missense	distal	5	no	8.793	8.869	EPSD	TCGA;ICGC;COSMIC	5.604	Up-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q9UQ35	SRRM2	O14757	CHEK1	T627	R623H	623	Missense	distal	-4	no	8.793	8.596	EPSD	TCGA;ICGC	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q9UQ35	SRRM2	O14757	CHEK1	S629	S635F	635	Missense	distal	6	no	9.936	10.339	EPSD	TCGA;ICGC	5.604	Up-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q9UQ35	SRRM2	O14757	CHEK1	S629	R634S	634	Missense	distal	5	no	9.936	10.039	EPSD	TCGA;ICGC;COSMIC	5.604	Up-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q9UQ35	SRRM2	O14757	CHEK1	S629	R622S	622	Missense	distal	-7	no	9.936	10.195	EPSD	TCGA;ICGC;COSMIC	5.604	Up-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q9UQ35	SRRM2	O14757	CHEK1	S629	R632Q	632	Missense	distal	3	no	9.936	10.998	EPSD	TCGA;ICGC;COSMIC	5.604	Up-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q9UQ35	SRRM2	O14757	CHEK1	S629	R623H	623	Missense	distal	-6	no	9.936	10.045	EPSD	TCGA;ICGC	5.604	Up-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q9UQ35	SRRM2	O14757	CHEK1	S635	S635F	635	Missense	central	0	yes	9.654	0.000	EPSD	TCGA;ICGC	5.604	Loss
CAMK_CAMKL_CHK1_CHEK1_ST	Q9UQ35	SRRM2	O14757	CHEK1	S635	S637C	637	Missense	proximal	2	no	9.654	9.292	EPSD	TCGA;ICGC;COSMIC	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q9UQ35	SRRM2	O14757	CHEK1	S635	R634S	634	Missense	proximal	-1	no	9.654	9.492	EPSD	TCGA;ICGC;COSMIC	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q9UQ35	SRRM2	O14757	CHEK1	S635	R632Q	632	Missense	distal	-3	no	9.654	2.447	EPSD	TCGA;ICGC;COSMIC	5.604	Loss
CAMK_CAMKL_CHK1_CHEK1_ST	Q9UQ35	SRRM2	O14757	CHEK1	S637	R643T	643	Missense	distal	6	no	11.078	11.301	EPSD	TCGA;ICGC;COSMIC	5.604	Up-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q9UQ35	SRRM2	O14757	CHEK1	S637	S635F	635	Missense	proximal	-2	no	11.078	11.368	EPSD	TCGA;ICGC	5.604	Up-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q9UQ35	SRRM2	O14757	CHEK1	S637	S637C	637	Missense	central	0	yes	11.078	0.000	EPSD	TCGA;ICGC;COSMIC	5.604	Loss
CAMK_CAMKL_CHK1_CHEK1_ST	Q9UQ35	SRRM2	O14757	CHEK1	S637	R634S	634	Missense	distal	-3	no	11.078	1.382	EPSD	TCGA;ICGC;COSMIC	5.604	Loss
CAMK_CAMKL_CHK1_CHEK1_ST	Q9UQ35	SRRM2	O14757	CHEK1	S637	R632Q	632	Missense	distal	-5	no	11.078	10.682	EPSD	TCGA;ICGC;COSMIC	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q9UQ35	SRRM2	O14757	CHEK1	S639	R643T	643	Missense	distal	4	no	10.214	10.175	EPSD	TCGA;ICGC;COSMIC	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q9UQ35	SRRM2	O14757	CHEK1	S639	S635F	635	Missense	distal	-4	no	10.214	9.972	EPSD	TCGA;ICGC	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q9UQ35	SRRM2	O14757	CHEK1	S639	S637C	637	Missense	proximal	-2	no	10.214	10.261	EPSD	TCGA;ICGC;COSMIC	5.604	Up-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q9UQ35	SRRM2	O14757	CHEK1	S639	R634S	634	Missense	distal	-5	no	10.214	10.003	EPSD	TCGA;ICGC;COSMIC	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q9UQ35	SRRM2	O14757	CHEK1	S639	R632Q	632	Missense	distal	-7	no	10.214	10.472	EPSD	TCGA;ICGC;COSMIC	5.604	Up-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q9UQ35	SRRM2	O14757	CHEK1	S644	R650K	650	Missense	distal	6	no	6.073	5.985	EPSD	TCGA;ICGC;COSMIC	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q9UQ35	SRRM2	O14757	CHEK1	S644	R643T	643	Missense	proximal	-1	no	6.073	6.117	EPSD	TCGA;ICGC;COSMIC	5.604	Up-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q9UQ35	SRRM2	O14757	CHEK1	S644	S637C	637	Missense	distal	-7	no	6.073	5.086	EPSD	TCGA;ICGC;COSMIC	5.604	Loss
CAMK_CAMKL_CHK1_CHEK1_ST	Q9UQ35	SRRM2	O14757	CHEK1	S644	R648H	648	Missense	distal	4	no	6.073	6.235	EPSD	TCGA;ICGC;COSMIC	5.604	Up-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q9UQ35	SRRM2	O14757	CHEK1	S649	R650K	650	Missense	proximal	1	no	8.534	8.535	EPSD	TCGA;ICGC;COSMIC	5.604	Up-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q9UQ35	SRRM2	O14757	CHEK1	S649	R643T	643	Missense	distal	-6	no	8.534	8.684	EPSD	TCGA;ICGC;COSMIC	5.604	Up-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q9UQ35	SRRM2	O14757	CHEK1	S649	R648H	648	Missense	proximal	-1	no	8.534	8.660	EPSD	TCGA;ICGC;COSMIC	5.604	Up-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q9UQ35	SRRM2	O14757	CHEK1	T651	R650K	650	Missense	proximal	-1	no	9.375	9.226	EPSD	TCGA;ICGC;COSMIC	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q9UQ35	SRRM2	O14757	CHEK1	T651	R648H	648	Missense	distal	-3	no	9.375	3.565	EPSD	TCGA;ICGC;COSMIC	5.604	Loss
CAMK_CAMKL_CHK1_CHEK1_ST	Q9UQ35	SRRM2	O14757	CHEK1	S660	R659L	659	Missense	proximal	-1	no	11.050	11.149	EPSD	TCGA;ICGC;COSMIC	5.604	Up-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q9UQ35	SRRM2	O14757	CHEK1	T662	S669L	669	Missense	distal	7	no	8.408	8.400	EPSD	TCGA;ICGC;COSMIC	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q9UQ35	SRRM2	O14757	CHEK1	T662	R668L	668	Missense	distal	6	no	8.408	8.730	EPSD	TCGA;ICGC;COSMIC	5.604	Up-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q9UQ35	SRRM2	O14757	CHEK1	T662	R659L	659	Missense	distal	-3	no	8.408	-10.138	EPSD	TCGA;ICGC;COSMIC	5.604	Loss
CAMK_CAMKL_CHK1_CHEK1_ST	Q9UQ35	SRRM2	O14757	CHEK1	S669	S669L	669	Missense	central	0	yes	8.147	0.000	EPSD	TCGA;ICGC;COSMIC	5.604	Loss
CAMK_CAMKL_CHK1_CHEK1_ST	Q9UQ35	SRRM2	O14757	CHEK1	S669	R668L	668	Missense	proximal	-1	no	8.147	8.247	EPSD	TCGA;ICGC;COSMIC	5.604	Up-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q9UQ35	SRRM2	O14757	CHEK1	S671	S669L	669	Missense	proximal	-2	no	10.095	10.200	EPSD	TCGA;ICGC;COSMIC	5.604	Up-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q9UQ35	SRRM2	O14757	CHEK1	S671	R668L	668	Missense	distal	-3	no	10.095	-8.452	EPSD	TCGA;ICGC;COSMIC	5.604	Loss
CAMK_CAMKL_CHK1_CHEK1_ST	Q9UQ35	SRRM2	O14757	CHEK1	S671	R677C	677	Missense	distal	6	no	10.095	10.389	EPSD	TCGA;ICGC;COSMIC;CCLE	5.604	Up-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q9UQ35	SRRM2	O14757	CHEK1	T673	S669L	669	Missense	distal	-4	no	9.960	10.012	EPSD	TCGA;ICGC;COSMIC	5.604	Up-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q9UQ35	SRRM2	O14757	CHEK1	T673	R668L	668	Missense	distal	-5	no	9.960	12.936	EPSD	TCGA;ICGC;COSMIC	5.604	Up-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q9UQ35	SRRM2	O14757	CHEK1	T673	R677C	677	Missense	distal	4	no	9.960	10.063	EPSD	TCGA;ICGC;COSMIC;CCLE	5.604	Up-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q9UQ35	SRRM2	O14757	CHEK1	S683	R688M	688	Missense	distal	5	no	9.973	9.964	EPSD	TCGA;ICGC;COSMIC	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q9UQ35	SRRM2	O14757	CHEK1	S683	R677C	677	Missense	distal	-6	no	9.973	10.089	EPSD	TCGA;ICGC;COSMIC;CCLE	5.604	Up-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q9UQ35	SRRM2	O14757	CHEK1	T685	R688M	688	Missense	distal	3	no	9.371	9.286	EPSD	TCGA;ICGC;COSMIC	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q9UQ35	SRRM2	O14757	CHEK1	S692	R693W	693	Missense	proximal	1	no	5.825	5.795	EPSD	TCGA;ICGC;COSMIC	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q9UQ35	SRRM2	O14757	CHEK1	S692	R693Q	693	Missense	proximal	1	no	5.825	5.834	EPSD	TCGA;ICGC;COSMIC	5.604	Up-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q9UQ35	SRRM2	O14757	CHEK1	S692	R698K	698	Missense	distal	6	no	5.825	5.737	EPSD	TCGA;ICGC;COSMIC	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q9UQ35	SRRM2	O14757	CHEK1	S692	R693L	693	Missense	proximal	1	no	5.825	5.790	EPSD	TCGA;ICGC;COSMIC	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q9UQ35	SRRM2	O14757	CHEK1	S692	R695S	695	Missense	distal	3	no	5.825	5.827	EPSD	TCGA;ICGC;COSMIC	5.604	Up-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q9UQ35	SRRM2	O14757	CHEK1	S692	R688M	688	Missense	distal	-4	no	5.825	5.662	EPSD	TCGA;ICGC;COSMIC	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q9UQ35	SRRM2	O14757	CHEK1	S694	R693W	693	Missense	proximal	-1	no	11.190	11.307	EPSD	TCGA;ICGC;COSMIC	5.604	Up-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q9UQ35	SRRM2	O14757	CHEK1	S694	R693Q	693	Missense	proximal	-1	no	11.190	11.205	EPSD	TCGA;ICGC;COSMIC	5.604	Up-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q9UQ35	SRRM2	O14757	CHEK1	S694	R698K	698	Missense	distal	4	no	11.190	11.091	EPSD	TCGA;ICGC;COSMIC	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q9UQ35	SRRM2	O14757	CHEK1	S694	R693L	693	Missense	proximal	-1	no	11.190	11.289	EPSD	TCGA;ICGC;COSMIC	5.604	Up-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q9UQ35	SRRM2	O14757	CHEK1	S694	R695S	695	Missense	proximal	1	no	11.190	11.164	EPSD	TCGA;ICGC;COSMIC	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q9UQ35	SRRM2	O14757	CHEK1	S694	R688M	688	Missense	distal	-6	no	11.190	11.331	EPSD	TCGA;ICGC;COSMIC	5.604	Up-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q9UQ35	SRRM2	O14757	CHEK1	T696	R693W	693	Missense	distal	-3	no	8.455	-25.149	EPSD	TCGA;ICGC;COSMIC	5.604	Loss
CAMK_CAMKL_CHK1_CHEK1_ST	Q9UQ35	SRRM2	O14757	CHEK1	T696	R693Q	693	Missense	distal	-3	no	8.455	1.248	EPSD	TCGA;ICGC;COSMIC	5.604	Loss
CAMK_CAMKL_CHK1_CHEK1_ST	Q9UQ35	SRRM2	O14757	CHEK1	T696	R698K	698	Missense	proximal	2	no	8.455	9.141	EPSD	TCGA;ICGC;COSMIC	5.604	Up-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q9UQ35	SRRM2	O14757	CHEK1	T696	R693L	693	Missense	distal	-3	no	8.455	-10.092	EPSD	TCGA;ICGC;COSMIC	5.604	Loss
CAMK_CAMKL_CHK1_CHEK1_ST	Q9UQ35	SRRM2	O14757	CHEK1	T696	R695S	695	Missense	proximal	-1	no	8.455	8.293	EPSD	TCGA;ICGC;COSMIC	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q9UQ35	SRRM2	O14757	CHEK1	S702	R698K	698	Missense	distal	-4	no	8.184	8.285	EPSD	TCGA;ICGC;COSMIC	5.604	Up-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q9UQ35	SRRM2	O14757	CHEK1	S702	R695S	695	Missense	distal	-7	no	8.184	8.443	EPSD	TCGA;ICGC;COSMIC	5.604	Up-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q9UQ35	SRRM2	O14757	CHEK1	S704	R698K	698	Missense	distal	-6	no	8.404	8.394	EPSD	TCGA;ICGC;COSMIC	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q9UQ35	SRRM2	O14757	CHEK1	S704	R710C	710	Missense	distal	6	no	8.404	8.698	EPSD	TCGA;ICGC;COSMIC	5.604	Up-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q9UQ35	SRRM2	O14757	CHEK1	S706	R710C	710	Missense	distal	4	no	7.487	7.591	EPSD	TCGA;ICGC;COSMIC	5.604	Up-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q9UQ35	SRRM2	O14757	CHEK1	S713	R710C	710	Missense	distal	-3	no	9.425	1.334	EPSD	TCGA;ICGC;COSMIC	5.604	Loss
CAMK_CAMKL_CHK1_CHEK1_ST	Q9UQ35	SRRM2	O14757	CHEK1	S713	R716I	716	Missense	distal	3	no	9.425	9.053	EPSD	TCGA;ICGC;COSMIC	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q9UQ35	SRRM2	O14757	CHEK1	S713	R720I	720	Missense	distal	7	no	9.425	9.040	EPSD	TCGA;ICGC;COSMIC	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q9UQ35	SRRM2	O14757	CHEK1	S715	R710C	710	Missense	distal	-5	no	10.269	9.590	EPSD	TCGA;ICGC;COSMIC	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q9UQ35	SRRM2	O14757	CHEK1	S715	R716I	716	Missense	proximal	1	no	10.269	10.207	EPSD	TCGA;ICGC;COSMIC	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q9UQ35	SRRM2	O14757	CHEK1	S715	R720I	720	Missense	distal	5	no	10.269	10.229	EPSD	TCGA;ICGC;COSMIC	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q9UQ35	SRRM2	O14757	CHEK1	S724	G725D	725	Missense	proximal	1	no	9.792	9.880	EPSD	TCGA;ICGC;COSMIC	5.604	Up-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q9UQ35	SRRM2	O14757	CHEK1	S724	R720I	720	Missense	distal	-4	no	9.792	9.504	EPSD	TCGA;ICGC;COSMIC	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q9UQ35	SRRM2	O14757	CHEK1	S726	G725D	725	Missense	proximal	-1	no	9.372	9.323	EPSD	TCGA;ICGC;COSMIC	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q9UQ35	SRRM2	O14757	CHEK1	S726	R720I	720	Missense	distal	-6	no	9.372	9.451	EPSD	TCGA;ICGC;COSMIC	5.604	Up-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q9UQ35	SRRM2	O14757	CHEK1	T736	S737F	737	Missense	proximal	1	no	6.428	6.423	EPSD	TCGA;ICGC;COSMIC	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q9UQ35	SRRM2	O14757	CHEK1	T736	S743F	743	Missense	distal	7	no	6.428	5.998	EPSD	TCGA;ICGC;COSMIC	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q9UQ35	SRRM2	O14757	CHEK1	S743	S737F	737	Missense	distal	-6	no	6.639	6.912	EPSD	TCGA;ICGC;COSMIC	5.604	Up-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q9UQ35	SRRM2	O14757	CHEK1	S743	S743F	743	Missense	central	0	yes	6.639	0.000	EPSD	TCGA;ICGC;COSMIC	5.604	Loss
CAMK_CAMKL_CHK1_CHEK1_ST	Q9UQ35	SRRM2	O14757	CHEK1	S743	S745L	745	Missense	proximal	2	no	6.639	6.244	EPSD	TCGA;ICGC;COSMIC	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q9UQ35	SRRM2	O14757	CHEK1	S745	S743F	743	Missense	proximal	-2	no	8.179	8.468	EPSD	TCGA;ICGC;COSMIC	5.604	Up-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q9UQ35	SRRM2	O14757	CHEK1	S745	S745L	745	Missense	central	0	yes	8.179	0.000	EPSD	TCGA;ICGC;COSMIC	5.604	Loss
CAMK_CAMKL_CHK1_CHEK1_ST	Q9UQ35	SRRM2	O14757	CHEK1	S756	L762V	762	Missense	distal	6	no	9.432	9.299	EPSD	TCGA;ICGC;COSMIC	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q9UQ35	SRRM2	O14757	CHEK1	S756	S755Y	755	Missense	proximal	-1	no	9.432	9.761	EPSD	TCGA;ICGC;COSMIC	5.604	Up-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q9UQ35	SRRM2	O14757	CHEK1	S756	L762F	762	Missense	distal	6	no	9.432	9.426	EPSD	TCGA;ICGC;COSMIC	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q9UQ35	SRRM2	O14757	CHEK1	S756	S763C	763	Missense	distal	7	no	9.432	9.119	EPSD	TCGA;COSMIC	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q9UQ35	SRRM2	O14757	CHEK1	S756	R758Q	758	Missense	proximal	2	no	9.432	9.961	EPSD	TCGA;ICGC	5.604	Up-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q9UQ35	SRRM2	O14757	CHEK1	S756	S759R	759	Missense	distal	3	no	9.432	9.430	EPSD	TCGA;ICGC;COSMIC	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q9UQ35	SRRM2	O14757	CHEK1	S756	S756L	756	Missense	central	0	yes	9.432	0.000	EPSD	TCGA;ICGC;COSMIC	5.604	Loss
CAMK_CAMKL_CHK1_CHEK1_ST	Q9UQ35	SRRM2	O14757	CHEK1	S756	R753C	753	Missense	distal	-3	no	9.432	1.341	EPSD	TCGA;ICGC;COSMIC	5.604	Loss
CAMK_CAMKL_CHK1_CHEK1_ST	Q9UQ35	SRRM2	O14757	CHEK1	S756	I754M	754	Missense	proximal	-2	no	9.432	9.446	EPSD	TCGA;ICGC;COSMIC	5.604	Up-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q9UQ35	SRRM2	O14757	CHEK1	S761	L762V	762	Missense	proximal	1	no	7.275	7.277	EPSD	TCGA;ICGC;COSMIC	5.604	Up-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q9UQ35	SRRM2	O14757	CHEK1	S761	S755Y	755	Missense	distal	-6	no	7.275	7.437	EPSD	TCGA;ICGC;COSMIC	5.604	Up-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q9UQ35	SRRM2	O14757	CHEK1	S761	L762F	762	Missense	proximal	1	no	7.275	7.279	EPSD	TCGA;ICGC;COSMIC	5.604	Up-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q9UQ35	SRRM2	O14757	CHEK1	S761	S763C	763	Missense	proximal	2	no	7.275	6.914	EPSD	TCGA;COSMIC	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q9UQ35	SRRM2	O14757	CHEK1	S761	R758Q	758	Missense	distal	-3	no	7.275	0.068	EPSD	TCGA;ICGC	5.604	Loss
CAMK_CAMKL_CHK1_CHEK1_ST	Q9UQ35	SRRM2	O14757	CHEK1	S761	S759R	759	Missense	proximal	-2	no	7.275	7.374	EPSD	TCGA;ICGC;COSMIC	5.604	Up-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q9UQ35	SRRM2	O14757	CHEK1	S761	R766Q	766	Missense	distal	5	no	7.275	7.350	EPSD	TCGA;ICGC;COSMIC	5.604	Up-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q9UQ35	SRRM2	O14757	CHEK1	S761	S756L	756	Missense	distal	-5	no	7.275	10.463	EPSD	TCGA;ICGC;COSMIC	5.604	Up-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q9UQ35	SRRM2	O14757	CHEK1	S761	I754M	754	Missense	distal	-7	no	7.275	7.517	EPSD	TCGA;ICGC;COSMIC	5.604	Up-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q9UQ35	SRRM2	O14757	CHEK1	S763	L762V	762	Missense	proximal	-1	no	9.043	9.038	EPSD	TCGA;ICGC;COSMIC	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q9UQ35	SRRM2	O14757	CHEK1	S763	L762F	762	Missense	proximal	-1	no	9.043	9.056	EPSD	TCGA;ICGC;COSMIC	5.604	Up-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q9UQ35	SRRM2	O14757	CHEK1	S763	S763C	763	Missense	central	0	yes	9.043	0.000	EPSD	TCGA;COSMIC	5.604	Loss
CAMK_CAMKL_CHK1_CHEK1_ST	Q9UQ35	SRRM2	O14757	CHEK1	S763	R758Q	758	Missense	distal	-5	no	9.043	8.647	EPSD	TCGA;ICGC	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q9UQ35	SRRM2	O14757	CHEK1	S763	S759R	759	Missense	distal	-4	no	9.043	9.351	EPSD	TCGA;ICGC;COSMIC	5.604	Up-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q9UQ35	SRRM2	O14757	CHEK1	S763	R766Q	766	Missense	distal	3	no	9.043	10.105	EPSD	TCGA;ICGC;COSMIC	5.604	Up-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q9UQ35	SRRM2	O14757	CHEK1	S763	S756L	756	Missense	distal	-7	no	9.043	8.159	EPSD	TCGA;ICGC;COSMIC	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q9UQ35	SRRM2	O14757	CHEK1	S780	S783F	783	Missense	distal	3	no	11.388	11.577	EPSD	TCGA	5.604	Up-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q9UQ35	SRRM2	O14757	CHEK1	S780	R777H	777	Missense	distal	-3	no	11.388	5.579	EPSD	TCGA;ICGC;COSMIC	5.604	Loss
CAMK_CAMKL_CHK1_CHEK1_ST	Q9UQ35	SRRM2	O14757	CHEK1	S780	S780L	780	Missense	central	0	yes	11.388	0.000	EPSD	TCGA;ICGC;COSMIC	5.604	Loss
CAMK_CAMKL_CHK1_CHEK1_ST	Q9UQ35	SRRM2	O14757	CHEK1	S799	R795S	795	Missense	distal	-4	no	5.671	5.363	EPSD	TCGA;ICGC;COSMIC	5.604	Loss
CAMK_CAMKL_CHK1_CHEK1_ST	Q9UQ35	SRRM2	O14757	CHEK1	S799	R796P	796	Missense	distal	-3	no	5.671	-1.466	EPSD	TCGA;ICGC;COSMIC	5.604	Loss
CAMK_CAMKL_CHK1_CHEK1_ST	Q9UQ35	SRRM2	O14757	CHEK1	S799	P793S	793	Missense	distal	-6	no	5.671	5.574	EPSD	TCGA;ICGC;COSMIC	5.604	Loss
CAMK_CAMKL_CHK1_CHEK1_ST	Q9UQ35	SRRM2	O14757	CHEK1	S799	R796H	796	Missense	distal	-3	no	5.671	-0.138	EPSD	TCGA;ICGC;COSMIC	5.604	Loss
CAMK_CAMKL_CHK1_CHEK1_ST	Q9UQ35	SRRM2	O14757	CHEK1	S817	T810M	810	Missense	distal	-7	no	6.577	7.043	EPSD	TCGA;ICGC;COSMIC	5.604	Up-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q9UQ35	SRRM2	O14757	CHEK1	S817	S815I	815	Missense	proximal	-2	no	6.577	6.705	EPSD	TCGA;ICGC;COSMIC	5.604	Up-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q9UQ35	SRRM2	O14757	CHEK1	S819	S815I	815	Missense	distal	-4	no	7.934	7.955	EPSD	TCGA;ICGC;COSMIC	5.604	Up-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q9UQ35	SRRM2	O14757	CHEK1	S831	Q833R	833	Missense	proximal	2	no	8.136	7.607	EPSD	TCGA;ICGC;COSMIC	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q9UQ35	SRRM2	O14757	CHEK1	S831	S838L	838	Missense	distal	7	no	8.136	8.128	EPSD	TCGA;ICGC;COSMIC	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q9UQ35	SRRM2	O14757	CHEK1	S831	S836F	836	Missense	distal	5	no	8.136	7.811	EPSD	TCGA;ICGC;COSMIC	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q9UQ35	SRRM2	O14757	CHEK1	S836	Q833R	833	Missense	distal	-3	no	2.307	9.513	EPSD	TCGA;ICGC;COSMIC	5.604	Gain
CAMK_CAMKL_CHK1_CHEK1_ST	Q9UQ35	SRRM2	O14757	CHEK1	S887	T885A	885	Missense	proximal	-2	no	9.297	9.157	EPSD	TCGA;ICGC;COSMIC	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q9UQ35	SRRM2	O14757	CHEK1	S929	S931F	931	Missense	proximal	2	no	8.316	8.172	EPSD	TCGA;ICGC;COSMIC	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q9UQ35	SRRM2	O14757	CHEK1	S929	R928I	928	Missense	proximal	-1	no	8.316	8.272	EPSD	TCGA	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q9UQ35	SRRM2	O14757	CHEK1	S968	G971E	971	Missense	distal	3	no	4.234	5.782	EPSD	TCGA;ICGC	5.604	Gain
CAMK_CAMKL_CHK1_CHEK1_ST	Q9UQ35	SRRM2	O14757	CHEK1	S1101	E1107D	1107	Missense	distal	6	no	6.646	6.732	EPSD	TCGA;ICGC;COSMIC	5.604	Up-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q9UQ35	SRRM2	O14757	CHEK1	S1140	R1137K	1137	Missense	distal	-3	no	6.166	2.341	EPSD	TCGA	5.604	Loss
CAMK_CAMKL_CHK1_CHEK1_ST	Q9UQ35	SRRM2	O14757	CHEK1	S1140	P1146R	1146	Missense	distal	6	no	6.166	5.634	EPSD	TCGA;ICGC;COSMIC	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q9UQ35	SRRM2	O14757	CHEK1	S1140	Q1139P	1139	Missense	proximal	-1	no	6.166	6.437	EPSD	TCGA;ICGC;COSMIC	5.604	Up-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q9UQ35	SRRM2	O14757	CHEK1	S1140	P1133L	1133	Missense	distal	-7	no	6.166	5.952	EPSD	TCGA;ICGC;COSMIC	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q9UQ35	SRRM2	O14757	CHEK1	S1140	E1134K	1134	Missense	distal	-6	no	6.166	6.198	EPSD	TCGA;ICGC;COSMIC	5.604	Up-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q9UQ35	SRRM2	O14757	CHEK1	S1140	R1137M	1137	Missense	distal	-3	no	6.166	1.017	EPSD	TCGA;ICGC;COSMIC	5.604	Loss
CAMK_CAMKL_CHK1_CHEK1_ST	Q9UQ35	SRRM2	O14757	CHEK1	S1214	E1212Q	1212	Missense	proximal	-2	no	6.835	6.919	EPSD	TCGA;ICGC;COSMIC	5.604	Up-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q9UQ35	SRRM2	O14757	CHEK1	S1214	T1208S	1208	Missense	distal	-6	no	6.835	6.765	EPSD	TCGA;ICGC;COSMIC	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q9UQ35	SRRM2	O14757	CHEK1	S1214	R1207S	1207	Missense	distal	-7	no	6.835	7.094	EPSD	TCGA;ICGC;COSMIC	5.604	Up-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q9UQ35	SRRM2	O14757	CHEK1	S1258	K1261E	1261	Missense	distal	3	no	4.848	5.664	EPSD	TCGA;ICGC;COSMIC	5.604	Gain
CAMK_CAMKL_CHK1_CHEK1_ST	Q9UQ35	SRRM2	O14757	CHEK1	S1266	E1259Q	1259	Missense	distal	-7	no	6.016	5.792	EPSD	TCGA;ICGC;COSMIC	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q9UQ35	SRRM2	O14757	CHEK1	S1266	E1273K	1273	Missense	distal	7	no	6.016	5.851	EPSD	TCGA;ICGC;COSMIC	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q9UQ35	SRRM2	O14757	CHEK1	S1266	K1261E	1261	Missense	distal	-5	no	6.016	3.454	EPSD	TCGA;ICGC;COSMIC	5.604	Loss
CAMK_CAMKL_CHK1_CHEK1_ST	Q9UQ35	SRRM2	O14757	CHEK1	S1266	L1260P	1260	Missense	distal	-6	no	6.016	6.089	EPSD	TCGA;ICGC;COSMIC	5.604	Up-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q9UQ35	SRRM2	O14757	CHEK1	S1266	K1261T	1261	Missense	distal	-5	no	6.016	5.762	EPSD	TCGA;ICGC	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q9UQ35	SRRM2	O14757	CHEK1	S1266	M1263V	1263	Missense	distal	-3	no	6.016	2.701	EPSD	TCGA;ICGC	5.604	Loss
CAMK_CAMKL_CHK1_CHEK1_ST	Q9UQ35	SRRM2	O14757	CHEK1	S1326	G1328E	1328	Missense	proximal	2	no	6.442	7.056	EPSD	TCGA;ICGC	5.604	Up-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q9UQ35	SRRM2	O14757	CHEK1	S1415	D1408H	1408	Missense	distal	-7	no	7.237	7.148	EPSD	TCGA;ICGC;COSMIC	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q9UQ35	SRRM2	O14757	CHEK1	S1415	A1409V	1409	Missense	distal	-6	no	7.237	7.375	EPSD	TCGA;ICGC;COSMIC	5.604	Up-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q9UQ35	SRRM2	O14757	CHEK1	S1415	R1412I	1412	Missense	distal	-3	no	7.237	-1.521	EPSD	TCGA;ICGC;COSMIC	5.604	Loss
CAMK_CAMKL_CHK1_CHEK1_ST	Q9UQ35	SRRM2	O14757	CHEK1	S1419	S1424P	1424	Missense	distal	5	no	8.175	8.093	EPSD	TCGA;ICGC;COSMIC	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q9UQ35	SRRM2	O14757	CHEK1	S1419	R1412I	1412	Missense	distal	-7	no	8.175	7.792	EPSD	TCGA;ICGC;COSMIC	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q9UQ35	SRRM2	O14757	CHEK1	S1421	M1427I	1427	Missense	distal	6	no	6.266	5.908	EPSD	TCGA;ICGC;COSMIC	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q9UQ35	SRRM2	O14757	CHEK1	S1421	S1424P	1424	Missense	distal	3	no	6.266	6.596	EPSD	TCGA;ICGC;COSMIC	5.604	Up-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q9UQ35	SRRM2	O14757	CHEK1	S1436	D1429H	1429	Missense	distal	-7	no	12.624	12.535	EPSD	TCGA;ICGC;COSMIC	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q9UQ35	SRRM2	O14757	CHEK1	S1436	G1430V	1430	Missense	distal	-6	no	12.624	12.598	EPSD	TCGA;ICGC;COSMIC	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q9UQ35	SRRM2	O14757	CHEK1	S1441	R1448T	1448	Missense	distal	7	no	7.836	7.676	EPSD	TCGA;ICGC;COSMIC	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q9UQ35	SRRM2	O14757	CHEK1	S1441	P1445R	1445	Missense	distal	4	no	7.836	7.746	EPSD	TCGA;ICGC;COSMIC	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q9UQ35	SRRM2	O14757	CHEK1	S1441	G1446E	1446	Missense	distal	5	no	7.836	8.112	EPSD	TCGA;ICGC	5.604	Up-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q9UQ35	SRRM2	O14757	CHEK1	S1443	R1448T	1448	Missense	distal	5	no	5.936	5.817	EPSD	TCGA;ICGC;COSMIC	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q9UQ35	SRRM2	O14757	CHEK1	S1443	P1445R	1445	Missense	proximal	2	no	5.936	5.918	EPSD	TCGA;ICGC;COSMIC	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q9UQ35	SRRM2	O14757	CHEK1	S1443	G1446E	1446	Missense	distal	3	no	5.936	7.484	EPSD	TCGA;ICGC	5.604	Up-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q9UQ35	SRRM2	O14757	CHEK1	S1443	D1449N	1449	Missense	distal	6	no	5.936	6.254	EPSD	TCGA;ICGC	5.604	Up-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q9UQ35	SRRM2	O14757	CHEK1	S1451	R1448T	1448	Missense	distal	-3	no	9.066	-11.503	EPSD	TCGA;ICGC;COSMIC	5.604	Loss
CAMK_CAMKL_CHK1_CHEK1_ST	Q9UQ35	SRRM2	O14757	CHEK1	S1451	P1445R	1445	Missense	distal	-6	no	9.066	8.888	EPSD	TCGA;ICGC;COSMIC	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q9UQ35	SRRM2	O14757	CHEK1	S1451	G1446E	1446	Missense	distal	-5	no	9.066	7.845	EPSD	TCGA;ICGC	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q9UQ35	SRRM2	O14757	CHEK1	S1451	D1449N	1449	Missense	proximal	-2	no	9.066	9.207	EPSD	TCGA;ICGC	5.604	Up-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q9UQ35	SRRM2	O14757	CHEK1	S1474	E1479A	1479	Missense	distal	5	no	10.843	10.776	EPSD	TCGA;ICGC;COSMIC	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q9UQ35	SRRM2	O14757	CHEK1	S1474	D1481N	1481	Missense	distal	7	no	10.843	10.681	EPSD	TCGA;ICGC;COSMIC	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q9UQ35	SRRM2	O14757	CHEK1	S1474	R1475T	1475	Missense	proximal	1	no	10.843	10.825	EPSD	TCGA;ICGC;COSMIC	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q9UQ35	SRRM2	O14757	CHEK1	S1474	T1472M	1472	Missense	proximal	-2	no	10.843	10.731	EPSD	TCGA;ICGC;COSMIC	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q9UQ35	SRRM2	O14757	CHEK1	S1478	E1479A	1479	Missense	proximal	1	no	8.662	8.580	EPSD	TCGA;ICGC;COSMIC	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q9UQ35	SRRM2	O14757	CHEK1	S1478	D1481N	1481	Missense	distal	3	no	8.662	7.946	EPSD	TCGA;ICGC;COSMIC	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q9UQ35	SRRM2	O14757	CHEK1	S1478	R1475T	1475	Missense	distal	-3	no	8.662	-11.907	EPSD	TCGA;ICGC;COSMIC	5.604	Loss
CAMK_CAMKL_CHK1_CHEK1_ST	Q9UQ35	SRRM2	O14757	CHEK1	S1478	T1472M	1472	Missense	distal	-6	no	8.662	8.654	EPSD	TCGA;ICGC;COSMIC	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q9UQ35	SRRM2	O14757	CHEK1	S1497	S1501L	1501	Missense	distal	4	no	7.995	8.031	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	5.604	Up-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q9UQ35	SRRM2	O14757	CHEK1	S1497	P1493R	1493	Missense	distal	-4	no	7.995	8.067	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	5.604	Up-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q9UQ35	SRRM2	O14757	CHEK1	S1497	S1501A	1501	Missense	distal	4	no	7.995	8.188	EPSD;PhosphoSitePlus	TCGA;ICGC	5.604	Up-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q9UQ35	SRRM2	O14757	CHEK1	S1499	L1505P	1505	Missense	distal	6	no	8.804	9.014	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	5.604	Up-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q9UQ35	SRRM2	O14757	CHEK1	S1499	S1501L	1501	Missense	proximal	2	no	8.804	8.410	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q9UQ35	SRRM2	O14757	CHEK1	S1499	P1493R	1493	Missense	distal	-6	no	8.804	8.627	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q9UQ35	SRRM2	O14757	CHEK1	S1499	S1501A	1501	Missense	proximal	2	no	8.804	9.260	EPSD;PhosphoSitePlus	TCGA;ICGC	5.604	Up-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q9UQ35	SRRM2	O14757	CHEK1	S1501	L1505P	1505	Missense	distal	4	no	8.668	8.772	EPSD	TCGA;ICGC;COSMIC	5.604	Up-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q9UQ35	SRRM2	O14757	CHEK1	S1501	S1501L	1501	Missense	central	0	yes	8.668	0.000	EPSD	TCGA;ICGC;COSMIC	5.604	Loss
CAMK_CAMKL_CHK1_CHEK1_ST	Q9UQ35	SRRM2	O14757	CHEK1	S1501	S1501A	1501	Missense	central	0	yes	8.668	0.000	EPSD	TCGA;ICGC	5.604	Loss
CAMK_CAMKL_CHK1_CHEK1_ST	Q9UQ35	SRRM2	O14757	CHEK1	S1517	E1515Q	1515	Missense	proximal	-2	no	7.818	7.902	EPSD	TCGA;ICGC;COSMIC	5.604	Up-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q9UQ35	SRRM2	O14757	CHEK1	S1517	T1511I	1511	Missense	distal	-6	no	7.818	7.748	EPSD	TCGA;ICGC;COSMIC	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q9UQ35	SRRM2	O14757	CHEK1	S1519	E1515Q	1515	Missense	distal	-4	no	7.222	7.179	EPSD	TCGA;ICGC;COSMIC	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q9UQ35	SRRM2	O14757	CHEK1	S1519	K1526E	1526	Missense	distal	7	no	7.222	7.388	EPSD	TCGA;ICGC;COSMIC	5.604	Up-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q9UQ35	SRRM2	O14757	CHEK1	S1539	Q1543E	1543	Missense	distal	4	no	7.300	7.208	EPSD	TCGA;ICGC;COSMIC	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q9UQ35	SRRM2	O14757	CHEK1	S1539	S1539P	1539	Missense	central	0	yes	7.300	0.000	EPSD	TCGA;ICGC;COSMIC	5.604	Loss
CAMK_CAMKL_CHK1_CHEK1_ST	Q9UQ35	SRRM2	O14757	CHEK1	S1539	R1538C	1538	Missense	proximal	-1	no	7.300	7.335	EPSD	TCGA;ICGC;COSMIC	5.604	Up-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q9UQ35	SRRM2	O14757	CHEK1	S1539	P1532L	1532	Missense	distal	-7	no	7.300	7.085	EPSD	TCGA;ICGC;COSMIC	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q9UQ35	SRRM2	O14757	CHEK1	S1539	S1539L	1539	Missense	central	0	yes	7.300	0.000	EPSD	TCGA;ICGC;COSMIC	5.604	Loss
CAMK_CAMKL_CHK1_CHEK1_ST	Q9UQ35	SRRM2	O14757	CHEK1	S1541	Q1543E	1543	Missense	proximal	2	no	8.184	8.299	EPSD	TCGA;ICGC;COSMIC	5.604	Up-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q9UQ35	SRRM2	O14757	CHEK1	S1541	S1539P	1539	Missense	proximal	-2	no	8.184	8.468	EPSD	TCGA;ICGC;COSMIC	5.604	Up-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q9UQ35	SRRM2	O14757	CHEK1	S1541	R1538C	1538	Missense	distal	-3	no	8.184	0.092	EPSD	TCGA;ICGC;COSMIC	5.604	Loss
CAMK_CAMKL_CHK1_CHEK1_ST	Q9UQ35	SRRM2	O14757	CHEK1	S1541	S1539L	1539	Missense	proximal	-2	no	8.184	8.289	EPSD	TCGA;ICGC;COSMIC	5.604	Up-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q9UQ35	SRRM2	O14757	CHEK1	S1559	S1565Y	1565	Missense	distal	6	no	7.111	7.852	EPSD	TCGA;ICGC;COSMIC	5.604	Up-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q9UQ35	SRRM2	O14757	CHEK1	S1577	S1581L	1581	Missense	distal	4	no	7.120	7.157	EPSD	TCGA;ICGC;COSMIC	5.604	Up-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q9UQ35	SRRM2	O14757	CHEK1	S1577	R1570K	1570	Missense	distal	-7	no	7.120	8.300	EPSD	TCGA;ICGC	5.604	Up-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q9UQ35	SRRM2	O14757	CHEK1	S1579	S1581L	1581	Missense	proximal	2	no	7.043	6.648	EPSD	TCGA;ICGC;COSMIC	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q9UQ35	SRRM2	O14757	CHEK1	S1581	S1581L	1581	Missense	central	0	yes	7.711	0.000	EPSD	TCGA;ICGC;COSMIC	5.604	Loss
CAMK_CAMKL_CHK1_CHEK1_ST	Q9UQ35	SRRM2	O14757	CHEK1	S1616	P1622S	1622	Missense	distal	6	no	8.302	7.682	EPSD	TCGA;ICGC;COSMIC	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q9UQ35	SRRM2	O14757	CHEK1	S1638	R1645K	1645	Missense	distal	7	no	7.683	7.758	EPSD	TCGA;ICGC;COSMIC	5.604	Up-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q9UQ35	SRRM2	O14757	CHEK1	S1640	R1645K	1645	Missense	distal	5	no	7.474	7.598	EPSD	TCGA;ICGC;COSMIC	5.604	Up-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q9UQ35	SRRM2	O14757	CHEK1	S1640	P1647L	1647	Missense	distal	7	no	7.474	7.411	EPSD	TCGA;ICGC;COSMIC	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q9UQ35	SRRM2	O14757	CHEK1	S1648	R1645K	1645	Missense	distal	-3	no	12.260	8.434	EPSD	TCGA;ICGC;COSMIC	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q9UQ35	SRRM2	O14757	CHEK1	S1648	P1647L	1647	Missense	proximal	-1	no	12.260	12.073	EPSD	TCGA;ICGC;COSMIC	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q9UQ35	SRRM2	O14757	CHEK1	S1648	S1648Y	1648	Missense	central	0	yes	12.260	0.000	EPSD	TCGA;ICGC;COSMIC	5.604	Loss
CAMK_CAMKL_CHK1_CHEK1_ST	Q9UQ35	SRRM2	O14757	CHEK1	S1672	P1678R	1678	Missense	distal	6	no	10.112	9.580	EPSD	TCGA;ICGC;COSMIC	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q9UQ35	SRRM2	O14757	CHEK1	S1672	S1674L	1674	Missense	proximal	2	no	10.112	9.718	EPSD	TCGA;ICGC;COSMIC	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q9UQ35	SRRM2	O14757	CHEK1	S1672	R1673G	1673	Missense	proximal	1	no	10.112	10.103	EPSD	TCGA	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q9UQ35	SRRM2	O14757	CHEK1	S1690	R1692Q	1692	Missense	proximal	2	no	6.896	7.425	EPSD	TCGA;ICGC;COSMIC;GDSC;CCLE	5.604	Up-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q9UQ35	SRRM2	O14757	CHEK1	S1691	R1692Q	1692	Missense	proximal	1	no	5.807	5.815	EPSD	TCGA;ICGC;COSMIC;GDSC;CCLE	5.604	Up-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q9UQ35	SRRM2	O14757	CHEK1	S1711	R1705S	1705	Missense	distal	-6	no	6.961	7.041	EPSD	TCGA	5.604	Up-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q9UQ35	SRRM2	O14757	CHEK1	S1711	R1717H	1717	Missense	distal	6	no	6.961	7.249	EPSD	TCGA;ICGC;COSMIC	5.604	Up-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q9UQ35	SRRM2	O14757	CHEK1	S1711	S1718C	1718	Missense	distal	7	no	6.961	6.648	EPSD	TCGA;ICGC;COSMIC	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q9UQ35	SRRM2	O14757	CHEK1	S1711	R1708C	1708	Missense	distal	-3	no	6.961	-1.130	EPSD	TCGA;ICGC;COSMIC	5.604	Loss
CAMK_CAMKL_CHK1_CHEK1_ST	Q9UQ35	SRRM2	O14757	CHEK1	T1720	R1719I	1719	Missense	proximal	-1	no	7.375	7.331	EPSD	TCGA;ICGC;COSMIC	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q9UQ35	SRRM2	O14757	CHEK1	T1720	R1717H	1717	Missense	distal	-3	no	7.375	1.566	EPSD	TCGA;ICGC;COSMIC	5.604	Loss
CAMK_CAMKL_CHK1_CHEK1_ST	Q9UQ35	SRRM2	O14757	CHEK1	T1720	S1718C	1718	Missense	proximal	-2	no	7.375	7.423	EPSD	TCGA;ICGC;COSMIC	5.604	Up-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q9UQ35	SRRM2	O14757	CHEK1	S1729	S1731F	1731	Missense	proximal	2	no	6.212	6.067	EPSD	TCGA;ICGC;COSMIC	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q9UQ35	SRRM2	O14757	CHEK1	S1729	P1728L	1728	Missense	proximal	-1	no	6.212	6.025	EPSD	TCGA;ICGC;COSMIC	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q9UQ35	SRRM2	O14757	CHEK1	S1747	R1744Q	1744	Missense	distal	-3	no	10.408	3.201	EPSD	TCGA;ICGC;COSMIC	5.604	Loss
CAMK_CAMKL_CHK1_CHEK1_ST	Q9UQ35	SRRM2	O14757	CHEK1	S1747	R1743H	1743	Missense	distal	-4	no	10.408	10.210	EPSD	TCGA;ICGC	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q9UQ35	SRRM2	O14757	CHEK1	S1747	R1745W	1745	Missense	proximal	-2	no	10.408	10.529	EPSD	TCGA;ICGC	5.604	Up-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q9UQ35	SRRM2	O14757	CHEK1	S1749	R1744Q	1744	Missense	distal	-5	no	11.554	11.158	EPSD	TCGA;ICGC;COSMIC	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q9UQ35	SRRM2	O14757	CHEK1	S1749	R1743H	1743	Missense	distal	-6	no	11.554	11.663	EPSD	TCGA;ICGC	5.604	Up-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q9UQ35	SRRM2	O14757	CHEK1	S1749	R1745W	1745	Missense	distal	-4	no	11.554	10.792	EPSD	TCGA;ICGC	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q9UQ35	SRRM2	O14757	CHEK1	S1762	S1764L	1764	Missense	proximal	2	no	7.307	6.913	EPSD	TCGA;ICGC;COSMIC	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q9UQ35	SRRM2	O14757	CHEK1	S1762	R1761C	1761	Missense	proximal	-1	no	7.307	7.342	EPSD	TCGA;ICGC;COSMIC	5.604	Up-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q9UQ35	SRRM2	O14757	CHEK1	S1764	S1764L	1764	Missense	central	0	yes	10.026	0.000	EPSD	TCGA;ICGC;COSMIC	5.604	Loss
CAMK_CAMKL_CHK1_CHEK1_ST	Q9UQ35	SRRM2	O14757	CHEK1	S1764	R1761C	1761	Missense	distal	-3	no	10.026	1.934	EPSD	TCGA;ICGC;COSMIC	5.604	Loss
CAMK_CAMKL_CHK1_CHEK1_ST	Q9UQ35	SRRM2	O14757	CHEK1	S1775	R1778S	1778	Missense	distal	3	no	13.234	13.236	EPSD	TCGA;ICGC;COSMIC	5.604	Up-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q9UQ35	SRRM2	O14757	CHEK1	S1775	S1773F	1773	Missense	proximal	-2	no	13.234	13.523	EPSD	TCGA;ICGC;COSMIC	5.604	Up-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q9UQ35	SRRM2	O14757	CHEK1	T1784	R1778S	1778	Missense	distal	-6	no	6.236	6.316	EPSD	TCGA;ICGC;COSMIC	5.604	Up-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q9UQ35	SRRM2	O14757	CHEK1	T1784	R1783G	1783	Missense	proximal	-1	no	6.236	6.253	EPSD	TCGA;ICGC;COSMIC	5.604	Up-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q9UQ35	SRRM2	O14757	CHEK1	T1784	R1786Q	1786	Missense	proximal	2	no	6.236	6.765	EPSD	TCGA;ICGC;COSMIC;GDSC;CCLE	5.604	Up-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q9UQ35	SRRM2	O14757	CHEK1	S1791	R1786Q	1786	Missense	distal	-5	no	9.800	9.403	EPSD	TCGA;ICGC;COSMIC;GDSC;CCLE	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q9UQ35	SRRM2	O14757	CHEK1	S1793	R1786Q	1786	Missense	distal	-7	no	10.373	10.631	EPSD	TCGA;ICGC;COSMIC;GDSC;CCLE	5.604	Up-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q9UQ35	SRRM2	O14757	CHEK1	S1818	G1819D	1819	Missense	proximal	1	no	9.078	9.166	EPSD	TCGA;ICGC;COSMIC	5.604	Up-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q9UQ35	SRRM2	O14757	CHEK1	S1818	H1821Y	1821	Missense	distal	3	no	9.078	7.822	EPSD	TCGA;ICGC;COSMIC	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q9UQ35	SRRM2	O14757	CHEK1	S1818	R1812W	1812	Missense	distal	-6	no	9.078	9.398	EPSD	TCGA;ICGC;COSMIC	5.604	Up-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q9UQ35	SRRM2	O14757	CHEK1	S1830	S1830N	1830	Missense	central	0	yes	8.697	0.000	EPSD	TCGA;ICGC;COSMIC	5.604	Loss
CAMK_CAMKL_CHK1_CHEK1_ST	Q9UQ35	SRRM2	O14757	CHEK1	S1830	R1827W	1827	Missense	distal	-3	no	8.697	-24.906	EPSD	TCGA;ICGC;COSMIC;CCLE	5.604	Loss
CAMK_CAMKL_CHK1_CHEK1_ST	Q9UQ35	SRRM2	O14757	CHEK1	S1830	R1827Q	1827	Missense	distal	-3	no	8.697	1.490	EPSD	TCGA;COSMIC;GDSC;CCLE	5.604	Loss
CAMK_CAMKL_CHK1_CHEK1_ST	Q9UQ35	SRRM2	O14757	CHEK1	S1842	R1841H	1841	Missense	proximal	-1	no	9.900	10.025	EPSD	TCGA;ICGC;COSMIC	5.604	Up-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q9UQ35	SRRM2	O14757	CHEK1	T1844	R1841H	1841	Missense	distal	-3	no	8.740	2.931	EPSD	TCGA;ICGC;COSMIC	5.604	Loss
CAMK_CAMKL_CHK1_CHEK1_ST	Q9UQ35	SRRM2	O14757	CHEK1	S1852	R1853C	1853	Missense	proximal	1	no	8.816	8.806	EPSD	TCGA;ICGC;COSMIC	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q9UQ35	SRRM2	O14757	CHEK1	S1852	S1854P	1854	Missense	proximal	2	no	8.816	8.739	EPSD	TCGA;ICGC;COSMIC	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q9UQ35	SRRM2	O14757	CHEK1	S1852	S1852P	1852	Missense	central	0	yes	8.816	0.000	EPSD	TCGA;ICGC;COSMIC	5.604	Loss
CAMK_CAMKL_CHK1_CHEK1_ST	Q9UQ35	SRRM2	O14757	CHEK1	S1854	R1853C	1853	Missense	proximal	-1	no	8.432	8.467	EPSD	TCGA;ICGC;COSMIC	5.604	Up-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q9UQ35	SRRM2	O14757	CHEK1	S1854	S1854P	1854	Missense	central	0	yes	8.432	0.000	EPSD	TCGA;ICGC;COSMIC	5.604	Loss
CAMK_CAMKL_CHK1_CHEK1_ST	Q9UQ35	SRRM2	O14757	CHEK1	S1854	S1852P	1852	Missense	proximal	-2	no	8.432	8.716	EPSD	TCGA;ICGC;COSMIC	5.604	Up-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q9UQ35	SRRM2	O14757	CHEK1	S1854	P1860Q	1860	Missense	distal	6	no	8.432	7.894	EPSD	TCGA;ICGC;COSMIC	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q9UQ35	SRRM2	O14757	CHEK1	T1856	R1853C	1853	Missense	distal	-3	no	8.195	0.104	EPSD	TCGA;ICGC;COSMIC	5.604	Loss
CAMK_CAMKL_CHK1_CHEK1_ST	Q9UQ35	SRRM2	O14757	CHEK1	T1856	S1854P	1854	Missense	proximal	-2	no	8.195	8.479	EPSD	TCGA;ICGC;COSMIC	5.604	Up-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q9UQ35	SRRM2	O14757	CHEK1	T1856	R1863H	1863	Missense	distal	7	no	8.195	7.903	EPSD	TCGA;ICGC	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q9UQ35	SRRM2	O14757	CHEK1	T1856	S1852P	1852	Missense	distal	-4	no	8.195	8.432	EPSD	TCGA;ICGC;COSMIC	5.604	Up-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q9UQ35	SRRM2	O14757	CHEK1	T1856	P1860Q	1860	Missense	distal	4	no	8.195	8.106	EPSD	TCGA;ICGC;COSMIC	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q9UQ35	SRRM2	O14757	CHEK1	S1866	T1872S	1872	Missense	distal	6	no	10.039	9.728	EPSD	TCGA	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q9UQ35	SRRM2	O14757	CHEK1	S1866	H1873D	1873	Missense	distal	7	no	10.039	10.630	EPSD	TCGA;ICGC;COSMIC	5.604	Up-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q9UQ35	SRRM2	O14757	CHEK1	S1866	R1863H	1863	Missense	distal	-3	no	10.039	4.229	EPSD	TCGA;ICGC	5.604	Loss
CAMK_CAMKL_CHK1_CHEK1_ST	Q9UQ35	SRRM2	O14757	CHEK1	S1866	P1860Q	1860	Missense	distal	-6	no	10.039	9.943	EPSD	TCGA;ICGC;COSMIC	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q9UQ35	SRRM2	O14757	CHEK1	S1878	T1872S	1872	Missense	distal	-6	no	6.953	6.884	EPSD	TCGA	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q9UQ35	SRRM2	O14757	CHEK1	S1878	H1873D	1873	Missense	distal	-5	no	6.953	8.431	EPSD	TCGA;ICGC;COSMIC	5.604	Up-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q9UQ35	SRRM2	O14757	CHEK1	T1880	H1873D	1873	Missense	distal	-7	no	6.239	6.327	EPSD	TCGA;ICGC;COSMIC	5.604	Up-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q9UQ35	SRRM2	O14757	CHEK1	S1888	R1891Q	1891	Missense	distal	3	no	10.205	11.267	EPSD	TCGA;ICGC;COSMIC	5.604	Up-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q9UQ35	SRRM2	O14757	CHEK1	S1890	R1891Q	1891	Missense	proximal	1	no	7.529	7.537	EPSD	TCGA;ICGC;COSMIC	5.604	Up-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q9UQ35	SRRM2	O14757	CHEK1	T1892	R1899W	1899	Missense	distal	7	no	8.214	7.712	EPSD	TCGA;ICGC;COSMIC	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q9UQ35	SRRM2	O14757	CHEK1	T1892	R1891Q	1891	Missense	proximal	-1	no	8.214	8.229	EPSD	TCGA;ICGC;COSMIC	5.604	Up-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q9UQ35	SRRM2	O14757	CHEK1	S1900	R1899W	1899	Missense	proximal	-1	no	8.678	8.795	EPSD	TCGA;ICGC;COSMIC	5.604	Up-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q9UQ35	SRRM2	O14757	CHEK1	S1902	R1899W	1899	Missense	distal	-3	no	8.410	-25.193	EPSD	TCGA;ICGC;COSMIC	5.604	Loss
CAMK_CAMKL_CHK1_CHEK1_ST	Q9UQ35	SRRM2	O14757	CHEK1	S1902	R1909Q	1909	Missense	distal	7	no	8.410	8.565	EPSD	TCGA;ICGC;COSMIC	5.604	Up-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q9UQ35	SRRM2	O14757	CHEK1	T1904	R1899W	1899	Missense	distal	-5	no	8.797	7.938	EPSD	TCGA;ICGC;COSMIC	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q9UQ35	SRRM2	O14757	CHEK1	T1904	S1911F	1911	Missense	distal	7	no	8.797	8.367	EPSD	TCGA;ICGC;COSMIC	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q9UQ35	SRRM2	O14757	CHEK1	T1904	R1909Q	1909	Missense	distal	5	no	8.797	8.872	EPSD	TCGA;ICGC;COSMIC	5.604	Up-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q9UQ35	SRRM2	O14757	CHEK1	S1911	S1911F	1911	Missense	central	0	yes	10.154	0.000	EPSD	TCGA;ICGC;COSMIC	5.604	Loss
CAMK_CAMKL_CHK1_CHEK1_ST	Q9UQ35	SRRM2	O14757	CHEK1	S1911	R1909Q	1909	Missense	proximal	-2	no	10.154	10.200	EPSD	TCGA;ICGC;COSMIC	5.604	Up-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q9UQ35	SRRM2	O14757	CHEK1	S1913	S1911F	1911	Missense	proximal	-2	no	12.021	12.311	EPSD	TCGA;ICGC;COSMIC	5.604	Up-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q9UQ35	SRRM2	O14757	CHEK1	S1913	R1909Q	1909	Missense	distal	-4	no	12.021	12.181	EPSD	TCGA;ICGC;COSMIC	5.604	Up-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q9UQ35	SRRM2	O14757	CHEK1	S1923	R1926T	1926	Missense	distal	3	no	9.000	8.860	EPSD	TCGA;ICGC;COSMIC	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q9UQ35	SRRM2	O14757	CHEK1	S1925	R1926T	1926	Missense	proximal	1	no	10.440	10.422	EPSD	TCGA;ICGC;COSMIC	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q9UQ35	SRRM2	O14757	CHEK1	T1927	R1934H	1934	Missense	distal	7	no	9.219	8.926	EPSD	TCGA;ICGC;COSMIC	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q9UQ35	SRRM2	O14757	CHEK1	T1927	R1926T	1926	Missense	proximal	-1	no	9.219	9.262	EPSD	TCGA;ICGC;COSMIC	5.604	Up-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q9UQ35	SRRM2	O14757	CHEK1	S1935	R1934H	1934	Missense	proximal	-1	no	7.026	7.152	EPSD	TCGA;ICGC;COSMIC	5.604	Up-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q9UQ35	SRRM2	O14757	CHEK1	S1935	S1935P	1935	Missense	central	0	yes	7.026	0.000	EPSD	TCGA;ICGC;COSMIC	5.604	Loss
CAMK_CAMKL_CHK1_CHEK1_ST	Q9UQ35	SRRM2	O14757	CHEK1	S1937	R1943C	1943	Missense	distal	6	no	8.934	9.228	EPSD	TCGA;ICGC	5.604	Up-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q9UQ35	SRRM2	O14757	CHEK1	S1937	R1934H	1934	Missense	distal	-3	no	8.934	3.124	EPSD	TCGA;ICGC;COSMIC	5.604	Loss
CAMK_CAMKL_CHK1_CHEK1_ST	Q9UQ35	SRRM2	O14757	CHEK1	S1937	R1943L	1943	Missense	distal	6	no	8.934	9.256	EPSD	TCGA;ICGC;COSMIC	5.604	Up-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q9UQ35	SRRM2	O14757	CHEK1	S1937	S1935P	1935	Missense	proximal	-2	no	8.934	9.218	EPSD	TCGA;ICGC;COSMIC	5.604	Up-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q9UQ35	SRRM2	O14757	CHEK1	T1939	R1943C	1943	Missense	distal	4	no	8.050	8.154	EPSD	TCGA;ICGC	5.604	Up-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q9UQ35	SRRM2	O14757	CHEK1	T1939	R1934H	1934	Missense	distal	-5	no	8.050	5.585	EPSD	TCGA;ICGC;COSMIC	5.604	Loss
CAMK_CAMKL_CHK1_CHEK1_ST	Q9UQ35	SRRM2	O14757	CHEK1	T1939	R1943L	1943	Missense	distal	4	no	8.050	8.036	EPSD	TCGA;ICGC;COSMIC	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q9UQ35	SRRM2	O14757	CHEK1	T1939	S1935P	1935	Missense	distal	-4	no	8.050	8.286	EPSD	TCGA;ICGC;COSMIC	5.604	Up-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q9UQ35	SRRM2	O14757	CHEK1	T1941	R1943C	1943	Missense	proximal	2	no	10.178	9.912	EPSD	TCGA;ICGC	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q9UQ35	SRRM2	O14757	CHEK1	T1941	R1934H	1934	Missense	distal	-7	no	10.178	10.119	EPSD	TCGA;ICGC;COSMIC	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q9UQ35	SRRM2	O14757	CHEK1	T1941	R1943L	1943	Missense	proximal	2	no	10.178	9.879	EPSD	TCGA;ICGC;COSMIC	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q9UQ35	SRRM2	O14757	CHEK1	T1941	S1935P	1935	Missense	distal	-6	no	10.178	10.275	EPSD	TCGA;ICGC;COSMIC	5.604	Up-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q9UQ35	SRRM2	O14757	CHEK1	S1946	R1943C	1943	Missense	distal	-3	no	11.287	3.196	EPSD	TCGA;ICGC	5.604	Loss
CAMK_CAMKL_CHK1_CHEK1_ST	Q9UQ35	SRRM2	O14757	CHEK1	S1946	R1943L	1943	Missense	distal	-3	no	11.287	-7.260	EPSD	TCGA;ICGC;COSMIC	5.604	Loss
CAMK_CAMKL_CHK1_CHEK1_ST	Q9UQ35	SRRM2	O14757	CHEK1	S1948	R1943C	1943	Missense	distal	-5	no	10.690	10.012	EPSD	TCGA;ICGC	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q9UQ35	SRRM2	O14757	CHEK1	S1948	R1943L	1943	Missense	distal	-5	no	10.690	13.667	EPSD	TCGA;ICGC;COSMIC	5.604	Up-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q9UQ35	SRRM2	O14757	CHEK1	S1948	R1955H	1955	Missense	distal	7	no	10.690	10.397	EPSD	TCGA;ICGC;COSMIC	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q9UQ35	SRRM2	O14757	CHEK1	S1948	R1955C	1955	Missense	distal	7	no	10.690	10.284	EPSD	TCGA;ICGC;COSMIC	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q9UQ35	SRRM2	O14757	CHEK1	T1950	R1943C	1943	Missense	distal	-7	no	9.383	8.655	EPSD	TCGA;ICGC	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q9UQ35	SRRM2	O14757	CHEK1	T1950	R1943L	1943	Missense	distal	-7	no	9.383	8.758	EPSD	TCGA;ICGC;COSMIC	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q9UQ35	SRRM2	O14757	CHEK1	T1950	R1955H	1955	Missense	distal	5	no	9.383	9.399	EPSD	TCGA;ICGC;COSMIC	5.604	Up-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q9UQ35	SRRM2	O14757	CHEK1	T1950	R1955C	1955	Missense	distal	5	no	9.383	9.139	EPSD	TCGA;ICGC;COSMIC	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q9UQ35	SRRM2	O14757	CHEK1	S1958	S1958C	1958	Missense	central	0	yes	10.255	0.000	EPSD	TCGA;ICGC;COSMIC	5.604	Loss
CAMK_CAMKL_CHK1_CHEK1_ST	Q9UQ35	SRRM2	O14757	CHEK1	S1958	R1955H	1955	Missense	distal	-3	no	10.255	4.445	EPSD	TCGA;ICGC;COSMIC	5.604	Loss
CAMK_CAMKL_CHK1_CHEK1_ST	Q9UQ35	SRRM2	O14757	CHEK1	S1958	R1955C	1955	Missense	distal	-3	no	10.255	2.163	EPSD	TCGA;ICGC;COSMIC	5.604	Loss
CAMK_CAMKL_CHK1_CHEK1_ST	Q9UQ35	SRRM2	O14757	CHEK1	S1960	S1958C	1958	Missense	proximal	-2	no	11.578	11.626	EPSD	TCGA;ICGC;COSMIC	5.604	Up-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q9UQ35	SRRM2	O14757	CHEK1	S1960	R1955H	1955	Missense	distal	-5	no	11.578	9.113	EPSD	TCGA;ICGC;COSMIC	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q9UQ35	SRRM2	O14757	CHEK1	S1960	R1955C	1955	Missense	distal	-5	no	11.578	10.900	EPSD	TCGA;ICGC;COSMIC	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q9UQ35	SRRM2	O14757	CHEK1	T1962	S1958C	1958	Missense	distal	-4	no	9.102	9.037	EPSD	TCGA;ICGC;COSMIC	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q9UQ35	SRRM2	O14757	CHEK1	T1962	R1955H	1955	Missense	distal	-7	no	9.102	9.043	EPSD	TCGA;ICGC;COSMIC	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q9UQ35	SRRM2	O14757	CHEK1	T1962	R1955C	1955	Missense	distal	-7	no	9.102	8.374	EPSD	TCGA;ICGC;COSMIC	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q9UQ35	SRRM2	O14757	CHEK1	S1982	V1989I	1989	Missense	distal	7	no	11.918	11.497	EPSD	TCGA;ICGC;COSMIC	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q9UQ35	SRRM2	O14757	CHEK1	S1982	S1987Y	1987	Missense	distal	5	no	11.918	11.463	EPSD	TCGA;ICGC	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q9UQ35	SRRM2	O14757	CHEK1	S1984	R1991Q	1991	Missense	distal	7	no	9.464	9.619	EPSD	TCGA;ICGC;COSMIC	5.604	Up-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q9UQ35	SRRM2	O14757	CHEK1	S1984	V1989I	1989	Missense	distal	5	no	9.464	9.406	EPSD	TCGA;ICGC;COSMIC	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q9UQ35	SRRM2	O14757	CHEK1	S1984	S1987Y	1987	Missense	distal	3	no	9.464	8.236	EPSD	TCGA;ICGC	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q9UQ35	SRRM2	O14757	CHEK1	T1986	R1991Q	1991	Missense	distal	5	no	8.766	8.842	EPSD	TCGA;ICGC;COSMIC	5.604	Up-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q9UQ35	SRRM2	O14757	CHEK1	T1986	V1989I	1989	Missense	distal	3	no	8.766	8.053	EPSD	TCGA;ICGC;COSMIC	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q9UQ35	SRRM2	O14757	CHEK1	T1986	S1987Y	1987	Missense	proximal	1	no	8.766	8.749	EPSD	TCGA;ICGC	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q9UQ35	SRRM2	O14757	CHEK1	S1994	R1991Q	1991	Missense	distal	-3	no	10.602	3.395	EPSD	TCGA;ICGC;COSMIC	5.604	Loss
CAMK_CAMKL_CHK1_CHEK1_ST	Q9UQ35	SRRM2	O14757	CHEK1	S1994	S1994C	1994	Missense	central	0	yes	10.602	0.000	EPSD	TCGA;ICGC;COSMIC	5.604	Loss
CAMK_CAMKL_CHK1_CHEK1_ST	Q9UQ35	SRRM2	O14757	CHEK1	S1994	V1989I	1989	Missense	distal	-5	no	10.602	12.047	EPSD	TCGA;ICGC;COSMIC	5.604	Up-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q9UQ35	SRRM2	O14757	CHEK1	S1994	S1987Y	1987	Missense	distal	-7	no	10.602	8.944	EPSD	TCGA;ICGC	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q9UQ35	SRRM2	O14757	CHEK1	S1996	R1991Q	1991	Missense	distal	-5	no	9.955	9.559	EPSD	TCGA;ICGC;COSMIC	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q9UQ35	SRRM2	O14757	CHEK1	S1996	S1994C	1994	Missense	proximal	-2	no	9.955	10.003	EPSD	TCGA;ICGC;COSMIC	5.604	Up-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q9UQ35	SRRM2	O14757	CHEK1	S1996	V1989I	1989	Missense	distal	-7	no	9.955	9.519	EPSD	TCGA;ICGC;COSMIC	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q9UQ35	SRRM2	O14757	CHEK1	T1998	R1991Q	1991	Missense	distal	-7	no	8.160	8.418	EPSD	TCGA;ICGC;COSMIC	5.604	Up-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q9UQ35	SRRM2	O14757	CHEK1	T1998	S1994C	1994	Missense	distal	-4	no	8.160	8.094	EPSD	TCGA;ICGC;COSMIC	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q9UQ35	SRRM2	O14757	CHEK1	S2008	R2015C	2015	Missense	distal	7	no	10.311	9.905	EPSD	TCGA;ICGC;COSMIC	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q9UQ35	SRRM2	O14757	CHEK1	T2010	R2017H	2017	Missense	distal	7	no	7.039	6.747	EPSD	TCGA;ICGC;COSMIC	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q9UQ35	SRRM2	O14757	CHEK1	T2010	R2016H	2016	Missense	distal	6	no	7.039	7.327	EPSD	TCGA;ICGC;COSMIC	5.604	Up-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q9UQ35	SRRM2	O14757	CHEK1	T2010	R2015C	2015	Missense	distal	5	no	7.039	6.796	EPSD	TCGA;ICGC;COSMIC	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q9UQ35	SRRM2	O14757	CHEK1	S2018	R2017H	2017	Missense	proximal	-1	no	10.226	10.351	EPSD	TCGA;ICGC;COSMIC	5.604	Up-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q9UQ35	SRRM2	O14757	CHEK1	S2018	R2021Q	2021	Missense	distal	3	no	10.226	11.288	EPSD	TCGA;ICGC;COSMIC	5.604	Up-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q9UQ35	SRRM2	O14757	CHEK1	S2018	R2016H	2016	Missense	proximal	-2	no	10.226	10.290	EPSD	TCGA;ICGC;COSMIC	5.604	Up-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q9UQ35	SRRM2	O14757	CHEK1	S2018	R2015C	2015	Missense	distal	-3	no	10.226	2.134	EPSD	TCGA;ICGC;COSMIC	5.604	Loss
CAMK_CAMKL_CHK1_CHEK1_ST	Q9UQ35	SRRM2	O14757	CHEK1	S2020	R2017H	2017	Missense	distal	-3	no	10.148	4.339	EPSD	TCGA;ICGC;COSMIC	5.604	Loss
CAMK_CAMKL_CHK1_CHEK1_ST	Q9UQ35	SRRM2	O14757	CHEK1	S2020	R2021Q	2021	Missense	proximal	1	no	10.148	10.157	EPSD	TCGA;ICGC;COSMIC	5.604	Up-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q9UQ35	SRRM2	O14757	CHEK1	S2020	R2016H	2016	Missense	distal	-4	no	10.148	9.951	EPSD	TCGA;ICGC;COSMIC	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q9UQ35	SRRM2	O14757	CHEK1	S2020	R2015C	2015	Missense	distal	-5	no	10.148	9.470	EPSD	TCGA;ICGC;COSMIC	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q9UQ35	SRRM2	O14757	CHEK1	T2022	R2017H	2017	Missense	distal	-5	no	7.122	4.657	EPSD	TCGA;ICGC;COSMIC	5.604	Loss
CAMK_CAMKL_CHK1_CHEK1_ST	Q9UQ35	SRRM2	O14757	CHEK1	T2022	R2029H	2029	Missense	distal	7	no	7.122	6.829	EPSD	TCGA;ICGC;COSMIC	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q9UQ35	SRRM2	O14757	CHEK1	T2022	R2021Q	2021	Missense	proximal	-1	no	7.122	7.137	EPSD	TCGA;ICGC;COSMIC	5.604	Up-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q9UQ35	SRRM2	O14757	CHEK1	T2022	R2016H	2016	Missense	distal	-6	no	7.122	7.232	EPSD	TCGA;ICGC;COSMIC	5.604	Up-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q9UQ35	SRRM2	O14757	CHEK1	T2022	R2015C	2015	Missense	distal	-7	no	7.122	6.394	EPSD	TCGA;ICGC;COSMIC	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q9UQ35	SRRM2	O14757	CHEK1	S2030	R2029H	2029	Missense	proximal	-1	no	8.049	8.174	EPSD	TCGA;ICGC;COSMIC	5.604	Up-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q9UQ35	SRRM2	O14757	CHEK1	S2032	R2029H	2029	Missense	distal	-3	no	12.257	6.447	EPSD	TCGA;ICGC;COSMIC	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q9UQ35	SRRM2	O14757	CHEK1	S2032	P2038S	2038	Missense	distal	6	no	12.257	11.637	EPSD	TCGA;ICGC;COSMIC	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q9UQ35	SRRM2	O14757	CHEK1	T2034	R2029H	2029	Missense	distal	-5	no	6.689	4.224	EPSD	TCGA;ICGC;COSMIC	5.604	Loss
CAMK_CAMKL_CHK1_CHEK1_ST	Q9UQ35	SRRM2	O14757	CHEK1	T2034	P2038S	2038	Missense	distal	4	no	6.689	6.549	EPSD	TCGA;ICGC;COSMIC	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q9UQ35	SRRM2	O14757	CHEK1	S2042	R2043Q	2043	Missense	proximal	1	no	12.881	12.890	EPSD	TCGA;ICGC;CCLE	5.604	Up-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q9UQ35	SRRM2	O14757	CHEK1	S2042	P2038S	2038	Missense	distal	-4	no	12.881	12.645	EPSD	TCGA;ICGC;COSMIC	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q9UQ35	SRRM2	O14757	CHEK1	S2044	I2050N	2050	Missense	distal	6	no	9.101	9.193	EPSD	TCGA	5.604	Up-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q9UQ35	SRRM2	O14757	CHEK1	S2044	R2043Q	2043	Missense	proximal	-1	no	9.101	9.117	EPSD	TCGA;ICGC;CCLE	5.604	Up-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q9UQ35	SRRM2	O14757	CHEK1	S2044	P2038S	2038	Missense	distal	-6	no	9.101	9.004	EPSD	TCGA;ICGC;COSMIC	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q9UQ35	SRRM2	O14757	CHEK1	S2046	I2050N	2050	Missense	distal	4	no	8.169	8.137	EPSD	TCGA	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q9UQ35	SRRM2	O14757	CHEK1	S2046	R2043Q	2043	Missense	distal	-3	no	8.169	0.962	EPSD	TCGA;ICGC;CCLE	5.604	Loss
CAMK_CAMKL_CHK1_CHEK1_ST	Q9UQ35	SRRM2	O14757	CHEK1	S2054	I2050N	2050	Missense	distal	-4	no	7.310	7.585	EPSD	TCGA	5.604	Up-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q9UQ35	SRRM2	O14757	CHEK1	S2054	R2055S	2055	Missense	proximal	1	no	7.310	7.285	EPSD	TCGA;ICGC;COSMIC	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q9UQ35	SRRM2	O14757	CHEK1	S2054	R2057C	2057	Missense	distal	3	no	7.310	6.363	EPSD	TCGA;ICGC;COSMIC	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q9UQ35	SRRM2	O14757	CHEK1	S2054	R2060Q	2060	Missense	distal	6	no	7.310	7.304	EPSD	TCGA;ICGC;COSMIC	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q9UQ35	SRRM2	O14757	CHEK1	S2056	I2050N	2050	Missense	distal	-6	no	10.857	10.899	EPSD	TCGA	5.604	Up-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q9UQ35	SRRM2	O14757	CHEK1	S2056	R2055S	2055	Missense	proximal	-1	no	10.857	10.696	EPSD	TCGA;ICGC;COSMIC	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q9UQ35	SRRM2	O14757	CHEK1	S2056	R2057C	2057	Missense	proximal	1	no	10.857	10.847	EPSD	TCGA;ICGC;COSMIC	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q9UQ35	SRRM2	O14757	CHEK1	S2056	R2060Q	2060	Missense	distal	4	no	10.857	10.856	EPSD	TCGA;ICGC;COSMIC	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q9UQ35	SRRM2	O14757	CHEK1	T2058	R2055S	2055	Missense	distal	-3	no	7.889	-1.807	EPSD	TCGA;ICGC;COSMIC	5.604	Loss
CAMK_CAMKL_CHK1_CHEK1_ST	Q9UQ35	SRRM2	O14757	CHEK1	T2058	R2057C	2057	Missense	proximal	-1	no	7.889	7.924	EPSD	TCGA;ICGC;COSMIC	5.604	Up-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q9UQ35	SRRM2	O14757	CHEK1	T2058	R2060Q	2060	Missense	proximal	2	no	7.889	8.418	EPSD	TCGA;ICGC;COSMIC	5.604	Up-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q9UQ35	SRRM2	O14757	CHEK1	S2081	R2087H	2087	Missense	distal	6	no	10.233	10.521	EPSD	TCGA;ICGC;COSMIC	5.604	Up-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q9UQ35	SRRM2	O14757	CHEK1	S2083	R2087H	2087	Missense	distal	4	no	5.552	5.713	EPSD	TCGA;ICGC;COSMIC	5.604	Gain
CAMK_CAMKL_CHK1_CHEK1_ST	Q9UQ35	SRRM2	O14757	CHEK1	S2090	R2097I	2097	Missense	distal	7	no	10.934	10.550	EPSD	TCGA;ICGC;COSMIC	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q9UQ35	SRRM2	O14757	CHEK1	S2090	P2093S	2093	Missense	distal	3	no	10.934	10.605	EPSD	TCGA;ICGC;COSMIC	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q9UQ35	SRRM2	O14757	CHEK1	S2090	R2087H	2087	Missense	distal	-3	no	10.934	5.125	EPSD	TCGA;ICGC;COSMIC	5.604	Loss
CAMK_CAMKL_CHK1_CHEK1_ST	Q9UQ35	SRRM2	O14757	CHEK1	T2092	R2097I	2097	Missense	distal	5	no	7.816	7.775	EPSD	TCGA;ICGC;COSMIC	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q9UQ35	SRRM2	O14757	CHEK1	T2092	P2093S	2093	Missense	proximal	1	no	7.816	7.852	EPSD	TCGA;ICGC;COSMIC	5.604	Up-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q9UQ35	SRRM2	O14757	CHEK1	T2092	H2099Y	2099	Missense	distal	7	no	7.816	7.501	EPSD	TCGA;ICGC;COSMIC	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q9UQ35	SRRM2	O14757	CHEK1	T2092	H2099N	2099	Missense	distal	7	no	7.816	8.245	EPSD	TCGA;ICGC;COSMIC	5.604	Up-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q9UQ35	SRRM2	O14757	CHEK1	T2092	R2087H	2087	Missense	distal	-5	no	7.816	5.350	EPSD	TCGA;ICGC;COSMIC	5.604	Loss
CAMK_CAMKL_CHK1_CHEK1_ST	Q9UQ35	SRRM2	O14757	CHEK1	S2100	R2097I	2097	Missense	distal	-3	no	5.727	-3.031	EPSD	TCGA;ICGC;COSMIC	5.604	Loss
CAMK_CAMKL_CHK1_CHEK1_ST	Q9UQ35	SRRM2	O14757	CHEK1	S2100	R2103Q	2103	Missense	distal	3	no	5.727	6.790	EPSD	TCGA;ICGC;COSMIC	5.604	Up-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q9UQ35	SRRM2	O14757	CHEK1	S2100	P2093S	2093	Missense	distal	-7	no	5.727	6.397	EPSD	TCGA;ICGC;COSMIC	5.604	Up-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q9UQ35	SRRM2	O14757	CHEK1	S2100	H2099Y	2099	Missense	proximal	-1	no	5.727	5.770	EPSD	TCGA;ICGC;COSMIC	5.604	Up-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q9UQ35	SRRM2	O14757	CHEK1	S2100	H2099N	2099	Missense	proximal	-1	no	5.727	5.659	EPSD	TCGA;ICGC;COSMIC	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q9UQ35	SRRM2	O14757	CHEK1	S2132	R2129C	2129	Missense	distal	-3	no	12.872	4.781	EPSD	TCGA;ICGC;COSMIC;GDSC	5.604	Loss
CAMK_CAMKL_CHK1_CHEK1_ST	Q9UQ35	SRRM2	O14757	CHEK1	S2132	P2126L	2126	Missense	distal	-6	no	12.872	12.799	EPSD	TCGA;ICGC	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q9UQ35	SRRM2	O14757	CHEK1	S2209	R2207T	2207	Missense	proximal	-2	no	10.101	10.256	EPSD	TCGA;ICGC;COSMIC	5.604	Up-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q9UQ35	SRRM2	O14757	CHEK1	S2209	A2202T	2202	Missense	distal	-7	no	10.101	8.784	EPSD	TCGA;ICGC;COSMIC	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q9UQ35	SRRM2	O14757	CHEK1	S2209	R2207I	2207	Missense	proximal	-2	no	10.101	10.130	EPSD	TCGA;ICGC	5.604	Up-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q9UQ35	SRRM2	O14757	CHEK1	T2261	A2265S	2265	Missense	distal	4	no	5.910	5.717	EPSD	TCGA;ICGC;COSMIC	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q9UQ35	SRRM2	O14757	CHEK1	T2291	P2290L	2290	Missense	proximal	-1	no	8.619	8.432	EPSD	TCGA;ICGC	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q9UQ35	SRRM2	O14757	CHEK1	T2302	P2303Q	2303	Missense	proximal	1	no	7.234	7.306	EPSD	TCGA;ICGC;COSMIC	5.604	Up-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q9UQ35	SRRM2	O14757	CHEK1	T2302	T2302P	2302	Missense	central	0	yes	7.234	0.000	EPSD	TCGA;ICGC;COSMIC	5.604	Loss
CAMK_CAMKL_CHK1_CHEK1_ST	Q9UQ35	SRRM2	O14757	CHEK1	S2314	L2311V	2311	Missense	distal	-3	no	-3.901	6.183	EPSD	TCGA;ICGC;COSMIC	5.604	Gain
CAMK_CAMKL_CHK1_CHEK1_ST	Q9UQ35	SRRM2	O14757	CHEK1	T2316	P2318S	2318	Missense	proximal	2	no	6.674	6.751	EPSD	TCGA;ICGC;COSMIC	5.604	Up-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q9UQ35	SRRM2	O14757	CHEK1	T2316	L2311V	2311	Missense	distal	-5	no	6.674	3.197	EPSD	TCGA;ICGC;COSMIC	5.604	Loss
CAMK_CAMKL_CHK1_CHEK1_ST	Q9UQ35	SRRM2	O14757	CHEK1	S2343	R2342W	2342	Missense	proximal	-1	no	5.723	5.841	EPSD	TCGA;ICGC;COSMIC	5.604	Up-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q9UQ35	SRRM2	O14757	CHEK1	S2343	L2338M	2338	Missense	distal	-5	no	5.723	1.350	EPSD	TCGA;ICGC;COSMIC	5.604	Loss
CAMK_CAMKL_CHK1_CHEK1_ST	Q9UQ35	SRRM2	O14757	CHEK1	S2407	A2413P	2413	Missense	distal	6	no	13.696	13.927	EPSD	TCGA;ICGC;COSMIC	5.604	Up-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q9UQ35	SRRM2	O14757	CHEK1	S2407	P2410S	2410	Missense	distal	3	no	13.696	13.366	EPSD	TCGA;ICGC;COSMIC	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q9UQ35	SRRM2	O14757	CHEK1	S2407	P2414S	2414	Missense	distal	7	no	13.696	13.641	EPSD	TCGA;ICGC	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q9UQ35	SRRM2	O14757	CHEK1	S2407	A2413T	2413	Missense	distal	6	no	13.696	13.618	EPSD	TCGA;ICGC;COSMIC	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q9UQ35	SRRM2	O14757	CHEK1	S2407	R2404Q	2404	Missense	distal	-3	no	13.696	6.489	EPSD	TCGA;ICGC;COSMIC	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q9UQ35	SRRM2	O14757	CHEK1	T2409	A2413P	2413	Missense	distal	4	no	6.681	6.628	EPSD	TCGA;ICGC;COSMIC	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q9UQ35	SRRM2	O14757	CHEK1	T2409	Q2416H	2416	Missense	distal	7	no	6.681	6.234	EPSD	TCGA;ICGC	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q9UQ35	SRRM2	O14757	CHEK1	T2409	P2410S	2410	Missense	proximal	1	no	6.681	6.718	EPSD	TCGA;ICGC;COSMIC	5.604	Up-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q9UQ35	SRRM2	O14757	CHEK1	T2409	P2414S	2414	Missense	distal	5	no	6.681	6.763	EPSD	TCGA;ICGC	5.604	Up-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q9UQ35	SRRM2	O14757	CHEK1	T2409	A2413T	2413	Missense	distal	4	no	6.681	6.499	EPSD	TCGA;ICGC;COSMIC	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q9UQ35	SRRM2	O14757	CHEK1	T2409	R2404Q	2404	Missense	distal	-5	no	6.681	6.285	EPSD	TCGA;ICGC;COSMIC	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q9UQ35	SRRM2	O14757	CHEK1	S2421	R2423Q	2423	Missense	proximal	2	no	7.443	7.972	EPSD	TCGA;ICGC;COSMIC;CCLE	5.604	Up-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q9UQ35	SRRM2	O14757	CHEK1	S2421	Q2416H	2416	Missense	distal	-5	no	7.443	5.374	EPSD	TCGA;ICGC	5.604	Loss
CAMK_CAMKL_CHK1_CHEK1_ST	Q9UQ35	SRRM2	O14757	CHEK1	S2421	P2414S	2414	Missense	distal	-7	no	7.443	8.113	EPSD	TCGA;ICGC	5.604	Up-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q9UQ35	SRRM2	O14757	CHEK1	S2426	R2423Q	2423	Missense	distal	-3	no	9.019	1.812	EPSD	TCGA;ICGC;COSMIC;CCLE	5.604	Loss
CAMK_CAMKL_CHK1_CHEK1_ST	Q9UQ35	SRRM2	O14757	CHEK1	T2467	S2472Y	2472	Missense	distal	5	no	5.883	5.429	EPSD	TCGA;ICGC	5.604	Loss
CAMK_CAMKL_CHK1_CHEK1_ST	Q9UQ35	SRRM2	O14757	CHEK1	S2533	S2535W	2535	Missense	proximal	2	no	7.570	7.300	EPSD	TCGA;ICGC;COSMIC	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q9UQ35	SRRM2	O14757	CHEK1	S2533	S2536L	2536	Missense	distal	3	no	7.570	7.136	EPSD	TCGA;ICGC;COSMIC	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q9UQ35	SRRM2	O14757	CHEK1	S2533	S2533Y	2533	Missense	central	0	yes	7.570	0.000	EPSD	TCGA;ICGC;COSMIC	5.604	Loss
CAMK_CAMKL_CHK1_CHEK1_ST	Q9UQ35	SRRM2	O14757	CHEK1	S2533	S2535L	2535	Missense	proximal	2	no	7.570	7.176	EPSD	TCGA;ICGC;COSMIC	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q9UQ35	SRRM2	O14757	CHEK1	S2533	S2538P	2538	Missense	distal	5	no	7.570	7.488	EPSD	TCGA;ICGC;COSMIC	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q9UQ35	SRRM2	O14757	CHEK1	S2533	R2530Q	2530	Missense	distal	-3	no	7.570	0.363	EPSD	TCGA;ICGC;COSMIC;GDSC;CCLE	5.604	Loss
CAMK_CAMKL_CHK1_CHEK1_ST	Q9UQ35	SRRM2	O14757	CHEK1	S2534	S2533Y	2533	Missense	proximal	-1	no	5.492	5.821	EPSD	TCGA;ICGC;COSMIC	5.604	Gain
CAMK_CAMKL_CHK1_CHEK1_ST	Q9UQ35	SRRM2	O14757	CHEK1	S2534	S2538P	2538	Missense	distal	4	no	5.492	5.632	EPSD	TCGA;ICGC;COSMIC	5.604	Gain
CAMK_CAMKL_CHK1_CHEK1_ST	Q9UQ35	SRRM2	O14757	CHEK1	S2534	R2530Q	2530	Missense	distal	-4	no	5.492	5.652	EPSD	TCGA;ICGC;COSMIC;GDSC;CCLE	5.604	Gain
CAMK_CAMKL_CHK1_CHEK1_ST	Q9UQ35	SRRM2	O14757	CHEK1	S2581	K2587N	2587	Missense	distal	6	no	10.877	11.011	EPSD	TCGA;ICGC	5.604	Up-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q9UQ35	SRRM2	O14757	CHEK1	S2608	S2607C	2607	Missense	proximal	-1	no	6.702	6.899	EPSD	TCGA;ICGC;COSMIC	5.604	Up-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q9UQ35	SRRM2	O14757	CHEK1	S2608	K2604T	2604	Missense	distal	-4	no	6.702	6.242	EPSD	TCGA;ICGC;COSMIC	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q9UQ35	SRRM2	O14757	CHEK1	S2608	R2603Q	2603	Missense	distal	-5	no	6.702	6.306	EPSD	TCGA;ICGC;COSMIC	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q9UQ35	SRRM2	O14757	CHEK1	S2609	S2607C	2607	Missense	proximal	-2	no	8.854	8.901	EPSD	TCGA;ICGC;COSMIC	5.604	Up-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q9UQ35	SRRM2	O14757	CHEK1	S2609	K2604T	2604	Missense	distal	-5	no	8.854	8.599	EPSD	TCGA;ICGC;COSMIC	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q9UQ35	SRRM2	O14757	CHEK1	S2609	R2603Q	2603	Missense	distal	-6	no	8.854	8.936	EPSD	TCGA;ICGC;COSMIC	5.604	Up-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q9UQ35	SRRM2	O14757	CHEK1	S2664	P2665H	2665	Missense	proximal	1	no	7.024	7.021	EPSD	TCGA;ICGC;COSMIC	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q9UQ35	SRRM2	O14757	CHEK1	S2677	S2675F	2675	Missense	proximal	-2	no	6.507	6.796	EPSD	TCGA;ICGC;COSMIC	5.604	Up-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q9UQ35	SRRM2	O14757	CHEK1	S2677	R2679W	2679	Missense	proximal	2	no	6.507	6.332	EPSD	TCGA;ICGC	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q9UQ35	SRRM2	O14757	CHEK1	S2677	R2679Q	2679	Missense	proximal	2	no	6.507	7.035	EPSD	TCGA;ICGC	5.604	Up-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q9UQ35	SRRM2	O14757	CHEK1	S2702	S2706L	2706	Missense	distal	4	no	8.080	8.116	EPSD	TCGA;ICGC;COSMIC	5.604	Up-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q9UQ35	SRRM2	O14757	CHEK1	S2702	R2708Q	2708	Missense	distal	6	no	8.080	8.073	EPSD	TCGA;ICGC	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q9UQ35	SRRM2	O14757	CHEK1	S2727	R2720Q	2720	Missense	distal	-7	no	8.884	9.142	EPSD	TCGA;ICGC	5.604	Up-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q9P2D1	CHD7	O14757	CHEK1	S417	P410S	410	Missense	distal	-7	no	9.414	10.084	EPSD	TCGA;ICGC;COSMIC	5.604	Up-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q9P2D1	CHD7	O14757	CHEK1	S417	V424F	424	Missense	distal	7	no	9.414	8.856	EPSD	TCGA;ICGC;COSMIC	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q9P2D1	CHD7	O14757	CHEK1	T689	K683R	683	Missense	distal	-6	no	7.870	7.880	EPSD	TCGA;ICGC;COSMIC	5.604	Up-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q9P2D1	CHD7	O14757	CHEK1	T1227	N1225S	1225	Missense	proximal	-2	no	6.721	6.532	PhosphoSitePlus	TCGA;ICGC;COSMIC	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q9P2D1	CHD7	O14757	CHEK1	T1227	G1233V	1233	Missense	distal	6	no	6.721	6.785	PhosphoSitePlus	TCGA;ICGC;COSMIC	5.604	Up-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q9P2D1	CHD7	O14757	CHEK1	T1227	T1227A	1227	Missense	central	0	yes	6.721	0.000	PhosphoSitePlus	TCGA;ICGC;COSMIC	5.604	Loss
CAMK_CAMKL_CHK1_CHEK1_ST	Q9P2D1	CHD7	O14757	CHEK1	T1635	R1632H	1632	Missense	distal	-3	no	9.656	3.846	EPSD	TCGA;ICGC;COSMIC	5.604	Loss
CAMK_CAMKL_CHK1_CHEK1_ST	Q9P2D1	CHD7	O14757	CHEK1	T1635	R1629C	1629	Missense	distal	-6	no	9.656	9.771	EPSD	TCGA;ICGC;COSMIC	5.604	Up-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q9P2D1	CHD7	O14757	CHEK1	S1882	E1877Q	1877	Missense	distal	-5	no	5.307	6.297	EPSD	TCGA;ICGC;COSMIC	5.604	Gain
CAMK_CAMKL_CHK1_CHEK1_ST	Q9P2D1	CHD7	O14757	CHEK1	S1882	E1877D	1877	Missense	distal	-5	no	5.307	5.707	EPSD	TCGA;ICGC;COSMIC	5.604	Gain
CAMK_CAMKL_CHK1_CHEK1_ST	Q9P2D1	CHD7	O14757	CHEK1	T2283	M2289I	2289	Missense	distal	6	no	10.714	10.356	EPSD	TCGA;ICGC;COSMIC	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q9P2D1	CHD7	O14757	CHEK1	T2283	F2287L	2287	Missense	distal	4	no	10.714	10.652	EPSD	TCGA;ICGC;COSMIC	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q9P2D1	CHD7	O14757	CHEK1	S2490	P2493R	2493	Missense	distal	3	no	6.783	6.451	EPSD	TCGA	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q9P2D1	CHD7	O14757	CHEK1	S2490	S2490L	2490	Missense	central	0	yes	6.783	0.000	EPSD	TCGA;ICGC;COSMIC	5.604	Loss
CAMK_CAMKL_CHK1_CHEK1_ST	Q9P2D1	CHD7	O14757	CHEK1	S2490	R2491C	2491	Missense	proximal	1	no	6.783	6.773	EPSD	TCGA;ICGC;COSMIC	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q9P2D1	CHD7	O14757	CHEK1	S2490	R2491H	2491	Missense	proximal	1	no	6.783	6.718	EPSD	TCGA;ICGC;COSMIC	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q9P2D1	CHD7	O14757	CHEK1	S2490	R2495S	2495	Missense	distal	5	no	6.783	6.886	EPSD	TCGA;ICGC;COSMIC	5.604	Up-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q9P2D1	CHD7	O14757	CHEK1	T2494	P2493R	2493	Missense	proximal	-1	no	11.447	11.162	EPSD	TCGA	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q9P2D1	CHD7	O14757	CHEK1	T2494	S2490L	2490	Missense	distal	-4	no	11.447	11.499	EPSD	TCGA;ICGC;COSMIC	5.604	Up-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q9P2D1	CHD7	O14757	CHEK1	T2494	R2491C	2491	Missense	distal	-3	no	11.447	3.356	EPSD	TCGA;ICGC;COSMIC	5.604	Loss
CAMK_CAMKL_CHK1_CHEK1_ST	Q9P2D1	CHD7	O14757	CHEK1	T2494	S2501F	2501	Missense	distal	7	no	11.447	11.017	EPSD	TCGA;ICGC;COSMIC	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q9P2D1	CHD7	O14757	CHEK1	T2494	L2498F	2498	Missense	distal	4	no	11.447	11.509	EPSD	TCGA;ICGC	5.604	Up-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q9P2D1	CHD7	O14757	CHEK1	T2494	R2491H	2491	Missense	distal	-3	no	11.447	5.638	EPSD	TCGA;ICGC;COSMIC	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q9P2D1	CHD7	O14757	CHEK1	T2494	R2495S	2495	Missense	proximal	1	no	11.447	11.421	EPSD	TCGA;ICGC;COSMIC	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q9P2D1	CHD7	O14757	CHEK1	S2533	S2535N	2535	Missense	proximal	2	no	5.504	5.686	EPSD	TCGA;ICGC;COSMIC	5.604	Gain
CAMK_CAMKL_CHK1_CHEK1_ST	Q9P2D1	CHD7	O14757	CHEK1	S2535	T2532M	2532	Missense	distal	-3	no	-6.464	8.956	EPSD	TCGA;ICGC;COSMIC	5.604	Gain
CAMK_CAMKL_CHK1_CHEK1_ST	Q9P2D1	CHD7	O14757	CHEK1	S2619	L2616R	2616	Missense	distal	-3	no	-10.397	8.150	EPSD	TCGA;ICGC;COSMIC	5.604	Gain
CAMK_CAMKL_CHK1_CHEK1_ST	Q9P2D1	CHD7	O14757	CHEK1	T2705	M2699K	2699	Missense	distal	-6	no	8.993	8.841	EPSD	TCGA;ICGC;COSMIC	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q9P2D1	CHD7	O14757	CHEK1	T2705	R2710L	2710	Missense	distal	5	no	8.993	8.853	EPSD	TCGA;ICGC;COSMIC	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q9P2D1	CHD7	O14757	CHEK1	S2715	R2710L	2710	Missense	distal	-5	no	3.399	6.376	EPSD	TCGA;ICGC;COSMIC	5.604	Gain
CAMK_CAMKL_CHK1_CHEK1_ST	Q13439	GOLGA4	O14757	CHEK1	S10	E11K	11	Missense	proximal	1	no	6.808	6.734	EPSD	TCGA;ICGC;COSMIC	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q13439	GOLGA4	O14757	CHEK1	S10	L5P	5	Missense	distal	-5	no	6.808	2.101	EPSD	TCGA;ICGC;COSMIC	5.604	Loss
CAMK_CAMKL_CHK1_CHEK1_ST	Q13439	GOLGA4	O14757	CHEK1	S10	K4E	4	Missense	distal	-6	no	6.808	6.776	EPSD	TCGA	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q13439	GOLGA4	O14757	CHEK1	S37	R34I	34	Missense	distal	-3	no	8.135	-0.623	EPSD	TCGA;ICGC;COSMIC	5.604	Loss
CAMK_CAMKL_CHK1_CHEK1_ST	Q13439	GOLGA4	O14757	CHEK1	T39	R34I	34	Missense	distal	-5	no	8.217	9.163	EPSD	TCGA;ICGC;COSMIC	5.604	Up-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q13439	GOLGA4	O14757	CHEK1	S41	R34I	34	Missense	distal	-7	no	6.884	6.501	EPSD	TCGA;ICGC;COSMIC	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q13439	GOLGA4	O14757	CHEK1	S89	V94M	94	Missense	distal	5	no	11.344	11.317	EPSD	TCGA;COSMIC	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q13439	GOLGA4	O14757	CHEK1	S98	R99Q	99	Missense	proximal	1	no	13.469	13.478	EPSD	TCGA;COSMIC	5.604	Up-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q13439	GOLGA4	O14757	CHEK1	S98	V94M	94	Missense	distal	-4	no	13.469	13.313	EPSD	TCGA;COSMIC	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q9UEY8	ADD3	O14757	CHEK1	S42	L45P	45	Missense	distal	3	no	7.170	7.933	EPSD	TCGA;ICGC;COSMIC	5.604	Up-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q9UEY8	ADD3	O14757	CHEK1	S180	I174K	174	Missense	distal	-6	no	10.811	10.722	EPSD	TCGA;ICGC;COSMIC	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q9UEY8	ADD3	O14757	CHEK1	S180	I175T	175	Missense	distal	-5	no	10.811	10.786	EPSD	TCGA;ICGC;COSMIC	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q9UEY8	ADD3	O14757	CHEK1	S402	A408T	408	Missense	distal	6	no	12.112	12.034	EPSD	TCGA;ICGC;COSMIC	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q9UEY8	ADD3	O14757	CHEK1	S402	D403Y	403	Missense	proximal	1	no	12.112	11.990	EPSD	TCGA;ICGC;COSMIC	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q9UEY8	ADD3	O14757	CHEK1	S402	R395G	395	Missense	distal	-7	no	12.112	12.150	EPSD	TCGA;ICGC;COSMIC	5.604	Up-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q9UEY8	ADD3	O14757	CHEK1	S402	P398S	398	Missense	distal	-4	no	12.112	11.876	EPSD	TCGA;ICGC;COSMIC	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q9UEY8	ADD3	O14757	CHEK1	S693	K686N	686	Missense	distal	-7	no	8.097	6.639	PhosphoSitePlus	TCGA;ICGC	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q9BW19	KIFC1	O14757	CHEK1	S26	G32V	32	Missense	distal	6	no	8.994	9.058	PhosphoSitePlus	TCGA;ICGC;COSMIC	5.604	Up-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q9BW19	KIFC1	O14757	CHEK1	S71	P70A	70	Missense	proximal	-1	no	5.969	5.855	EPSD	TCGA;ICGC;COSMIC	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q9BW19	KIFC1	O14757	CHEK1	T159	C153F	153	Missense	distal	-6	no	9.916	10.154	EPSD	TCGA;ICGC;COSMIC	5.604	Up-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q9BW19	KIFC1	O14757	CHEK1	T159	R152Q	152	Missense	distal	-7	no	9.916	10.174	EPSD	TCGA;ICGC;COSMIC	5.604	Up-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q9BW19	KIFC1	O14757	CHEK1	T159	R154H	154	Missense	distal	-5	no	9.916	7.450	EPSD	TCGA	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q9BW19	KIFC1	O14757	CHEK1	T326	G323R	323	Missense	distal	-3	no	4.733	12.508	EPSD	TCGA;ICGC;COSMIC	5.604	Gain
CAMK_CAMKL_CHK1_CHEK1_ST	Q9BW19	KIFC1	O14757	CHEK1	T359	G362A	362	Missense	distal	3	no	7.057	7.239	EPSD	TCGA;ICGC;COSMIC	5.604	Up-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q9BW19	KIFC1	O14757	CHEK1	T359	R356W	356	Missense	distal	-3	no	7.057	-26.546	EPSD	TCGA;ICGC;COSMIC	5.604	Loss
CAMK_CAMKL_CHK1_CHEK1_ST	Q9BW19	KIFC1	O14757	CHEK1	S540	R534W	534	Missense	distal	-6	no	9.068	9.388	EPSD	TCGA;ICGC;COSMIC;CCLE	5.604	Up-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q9BW19	KIFC1	O14757	CHEK1	S540	R537H	537	Missense	distal	-3	no	9.068	3.259	EPSD	TCGA;ICGC;COSMIC	5.604	Loss
CAMK_CAMKL_CHK1_CHEK1_ST	Q9BW19	KIFC1	O14757	CHEK1	S540	R534L	534	Missense	distal	-6	no	9.068	9.172	EPSD	TCGA;ICGC;COSMIC	5.604	Up-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q9BW19	KIFC1	O14757	CHEK1	S540	L544I	544	Missense	distal	4	no	9.068	9.083	EPSD	TCGA;ICGC;COSMIC	5.604	Up-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q9BW19	KIFC1	O14757	CHEK1	S540	E533K	533	Missense	distal	-7	no	9.068	9.765	EPSD	TCGA;ICGC;COSMIC	5.604	Up-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q9BW19	KIFC1	O14757	CHEK1	S540	R537C	537	Missense	distal	-3	no	9.068	0.977	EPSD	TCGA;ICGC;COSMIC	5.604	Loss
CAMK_CAMKL_CHK1_CHEK1_ST	Q9BW19	KIFC1	O14757	CHEK1	S648	E649K	649	Missense	proximal	1	no	6.706	6.632	EPSD	TCGA;ICGC;COSMIC	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q9BW19	KIFC1	O14757	CHEK1	S648	R655H	655	Missense	distal	7	no	6.706	6.413	EPSD	TCGA;ICGC;COSMIC	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q9BW19	KIFC1	O14757	CHEK1	S648	P642L	642	Missense	distal	-6	no	6.706	6.633	EPSD	TCGA;ICGC;COSMIC	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	P43243	MATR3	O14757	CHEK1	S54	R51C	51	Missense	distal	-3	no	12.242	4.150	EPSD	TCGA;ICGC;COSMIC	5.604	Loss
CAMK_CAMKL_CHK1_CHEK1_ST	P43243	MATR3	O14757	CHEK1	S63	A69T	69	Missense	distal	6	no	8.472	8.395	EPSD	TCGA;ICGC;COSMIC	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	P43243	MATR3	O14757	CHEK1	S63	H70Y	70	Missense	distal	7	no	8.472	8.158	EPSD	TCGA;ICGC;COSMIC	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	P43243	MATR3	O14757	CHEK1	T150	E151K	151	Missense	proximal	1	no	10.156	10.082	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	P43243	MATR3	O14757	CHEK1	T150	P154S	154	Missense	distal	4	no	10.156	10.016	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	P43243	MATR3	O14757	CHEK1	T166	R167W	167	Missense	proximal	1	no	6.691	6.661	EPSD	TCGA;ICGC;COSMIC	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	P43243	MATR3	O14757	CHEK1	T166	R167Q	167	Missense	proximal	1	no	6.691	6.699	EPSD	TCGA;ICGC;COSMIC	5.604	Up-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	P43243	MATR3	O14757	CHEK1	S188	R185T	185	Missense	distal	-3	no	9.262	-11.307	EPSD	TCGA;ICGC	5.604	Loss
CAMK_CAMKL_CHK1_CHEK1_ST	P43243	MATR3	O14757	CHEK1	S188	R192C	192	Missense	distal	4	no	9.262	9.366	EPSD	TCGA;ICGC;CCLE	5.604	Up-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	P43243	MATR3	O14757	CHEK1	S188	F189S	189	Missense	proximal	1	no	9.262	9.267	EPSD	TCGA;ICGC	5.604	Up-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	P43243	MATR3	O14757	CHEK1	S188	R185K	185	Missense	distal	-3	no	9.262	5.436	EPSD	TCGA;ICGC	5.604	Loss
CAMK_CAMKL_CHK1_CHEK1_ST	P43243	MATR3	O14757	CHEK1	S195	R192C	192	Missense	distal	-3	no	10.722	2.631	PhosphoSitePlus;EPSD	TCGA;ICGC;CCLE	5.604	Loss
CAMK_CAMKL_CHK1_CHEK1_ST	P43243	MATR3	O14757	CHEK1	S195	F189S	189	Missense	distal	-6	no	10.722	10.449	PhosphoSitePlus;EPSD	TCGA;ICGC	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	P43243	MATR3	O14757	CHEK1	S234	D233Y	233	Missense	proximal	-1	no	6.706	6.905	EPSD	TCGA;ICGC;COSMIC	5.604	Up-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	P43243	MATR3	O14757	CHEK1	S234	G227V	227	Missense	distal	-7	no	6.706	6.721	EPSD	TCGA;ICGC;COSMIC;CCLE	5.604	Up-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	P43243	MATR3	O14757	CHEK1	S248	Y250C	250	Missense	proximal	2	no	6.962	6.897	EPSD	TCGA;ICGC;COSMIC	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	P43243	MATR3	O14757	CHEK1	S248	R255C	255	Missense	distal	7	no	6.962	6.556	EPSD	TCGA;ICGC;COSMIC;CCLE	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	P43243	MATR3	O14757	CHEK1	S307	G312E	312	Missense	distal	5	no	6.619	6.895	EPSD	TCGA;ICGC;COSMIC	5.604	Up-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	P43243	MATR3	O14757	CHEK1	S307	I310M	310	Missense	distal	3	no	6.619	6.906	EPSD	TCGA	5.604	Up-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	P43243	MATR3	O14757	CHEK1	S307	H301Y	301	Missense	distal	-6	no	6.619	6.751	EPSD	TCGA;ICGC;COSMIC	5.604	Up-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	P43243	MATR3	O14757	CHEK1	S307	I310V	310	Missense	distal	3	no	6.619	7.332	EPSD	TCGA;ICGC;COSMIC	5.604	Up-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	P43243	MATR3	O14757	CHEK1	S307	V300I	300	Missense	distal	-7	no	6.619	6.182	EPSD	TCGA;ICGC;COSMIC	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	P43243	MATR3	O14757	CHEK1	S592	D590H	590	Missense	proximal	-2	no	6.533	6.649	EPSD	TCGA;ICGC;COSMIC	5.604	Up-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	P43243	MATR3	O14757	CHEK1	S596	D590H	590	Missense	distal	-6	no	10.374	10.576	EPSD	TCGA;ICGC;COSMIC	5.604	Up-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	P43243	MATR3	O14757	CHEK1	S759	P754L	754	Missense	distal	-5	no	2.341	7.048	EPSD	TCGA;ICGC;COSMIC	5.604	Gain
CAMK_CAMKL_CHK1_CHEK1_ST	P33992	MCM5	O14757	CHEK1	S423	S417L	417	Missense	distal	-6	no	11.644	11.668	EPSD	TCGA;COSMIC	5.604	Up-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	P33992	MCM5	O14757	CHEK1	S423	R425W	425	Missense	proximal	2	no	11.644	11.469	EPSD	TCGA;COSMIC	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	P33992	MCM5	O14757	CHEK1	S605	R598K	598	Missense	distal	-7	no	9.322	10.502	EPSD	TCGA;COSMIC	5.604	Up-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	P33992	MCM5	O14757	CHEK1	S605	R611W	611	Missense	distal	6	no	9.322	9.789	EPSD	TCGA;COSMIC;GDSC	5.604	Up-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	P33992	MCM5	O14757	CHEK1	T633	M626I	626	Missense	distal	-7	no	5.688	5.446	PhosphoSitePlus	TCGA;COSMIC;GDSC;CCLE	5.604	Loss
CAMK_CAMKL_CHK1_CHEK1_ST	Q96T58	SPEN	O14757	CHEK1	S43	P39S	39	Missense	distal	-4	no	10.511	10.275	EPSD	TCGA;ICGC;COSMIC	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q96T58	SPEN	O14757	CHEK1	T177	D172N	172	Missense	distal	-5	no	5.141	6.410	EPSD	TCGA;ICGC	5.604	Gain
CAMK_CAMKL_CHK1_CHEK1_ST	Q96T58	SPEN	O14757	CHEK1	S190	A196T	196	Missense	distal	6	no	6.239	6.162	EPSD	TCGA;ICGC;COSMIC	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q96T58	SPEN	O14757	CHEK1	S190	A185V	185	Missense	distal	-5	no	6.239	8.679	EPSD	TCGA;ICGC;COSMIC	5.604	Up-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q96T58	SPEN	O14757	CHEK1	S190	A185T	185	Missense	distal	-5	no	6.239	10.100	EPSD	TCGA;ICGC;COSMIC;GDSC	5.604	Up-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q96T58	SPEN	O14757	CHEK1	S244	S247L	247	Missense	distal	3	no	6.042	5.608	EPSD	TCGA;ICGC;COSMIC;CCLE	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q96T58	SPEN	O14757	CHEK1	S244	H246Y	246	Missense	proximal	2	no	6.042	5.822	EPSD	TCGA;ICGC;COSMIC	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q96T58	SPEN	O14757	CHEK1	S260	Q253E	253	Missense	distal	-7	no	8.135	8.360	EPSD	TCGA;ICGC;COSMIC	5.604	Up-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q96T58	SPEN	O14757	CHEK1	S260	R257I	257	Missense	distal	-3	no	8.135	-0.623	EPSD	TCGA;ICGC	5.604	Loss
CAMK_CAMKL_CHK1_CHEK1_ST	Q96T58	SPEN	O14757	CHEK1	S278	S278A	278	Missense	central	0	yes	7.149	0.000	EPSD	TCGA;ICGC;COSMIC	5.604	Loss
CAMK_CAMKL_CHK1_CHEK1_ST	Q96T58	SPEN	O14757	CHEK1	S278	G271D	271	Missense	distal	-7	no	7.149	7.141	EPSD	TCGA;ICGC;COSMIC	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q96T58	SPEN	O14757	CHEK1	S623	Y626C	626	Missense	distal	3	no	7.308	7.586	EPSD	TCGA;ICGC;COSMIC	5.604	Up-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q96T58	SPEN	O14757	CHEK1	S623	Q628E	628	Missense	distal	5	no	7.308	7.422	EPSD	TCGA;ICGC;COSMIC	5.604	Up-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q96T58	SPEN	O14757	CHEK1	S623	R630C	630	Missense	distal	7	no	7.308	6.903	EPSD	TCGA;ICGC;COSMIC	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q96T58	SPEN	O14757	CHEK1	S623	R630H	630	Missense	distal	7	no	7.308	7.016	EPSD	TCGA;ICGC;COSMIC	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q96T58	SPEN	O14757	CHEK1	S646	R653Q	653	Missense	distal	7	no	6.338	6.492	EPSD	TCGA;ICGC;COSMIC	5.604	Up-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q96T58	SPEN	O14757	CHEK1	S727	I722T	722	Missense	distal	-5	no	8.901	8.877	EPSD	TCGA;ICGC;COSMIC	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q96T58	SPEN	O14757	CHEK1	S727	R733H	733	Missense	distal	6	no	8.901	9.189	EPSD	TCGA;ICGC	5.604	Up-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q96T58	SPEN	O14757	CHEK1	S727	R724Q	724	Missense	distal	-3	no	8.901	1.694	EPSD	TCGA;ICGC;COSMIC	5.604	Loss
CAMK_CAMKL_CHK1_CHEK1_ST	Q96T58	SPEN	O14757	CHEK1	S736	R733H	733	Missense	distal	-3	no	13.238	7.429	EPSD	TCGA;ICGC	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q96T58	SPEN	O14757	CHEK1	S736	G738A	738	Missense	proximal	2	no	13.238	13.759	EPSD	TCGA;ICGC;COSMIC	5.604	Up-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q96T58	SPEN	O14757	CHEK1	S757	R762W	762	Missense	distal	5	no	6.656	6.487	EPSD	TCGA;ICGC;COSMIC	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q96T58	SPEN	O14757	CHEK1	S765	S765N	765	Missense	central	0	yes	8.886	0.000	EPSD	TCGA;ICGC;COSMIC	5.604	Loss
CAMK_CAMKL_CHK1_CHEK1_ST	Q96T58	SPEN	O14757	CHEK1	S765	R762W	762	Missense	distal	-3	no	8.886	-24.717	EPSD	TCGA;ICGC;COSMIC	5.604	Loss
CAMK_CAMKL_CHK1_CHEK1_ST	Q96T58	SPEN	O14757	CHEK1	S765	S765C	765	Missense	central	0	yes	8.886	0.000	EPSD	TCGA;ICGC;COSMIC	5.604	Loss
CAMK_CAMKL_CHK1_CHEK1_ST	Q96T58	SPEN	O14757	CHEK1	S830	S835C	835	Missense	distal	5	no	6.492	6.145	EPSD	TCGA;ICGC;COSMIC	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q96T58	SPEN	O14757	CHEK1	S830	S836L	836	Missense	distal	6	no	6.492	6.901	EPSD	TCGA;ICGC;COSMIC	5.604	Up-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q96T58	SPEN	O14757	CHEK1	S830	S830F	830	Missense	central	0	yes	6.492	0.000	EPSD	TCGA;ICGC;COSMIC	5.604	Loss
CAMK_CAMKL_CHK1_CHEK1_ST	Q96T58	SPEN	O14757	CHEK1	S832	S835C	835	Missense	distal	3	no	6.015	5.065	EPSD	TCGA;ICGC;COSMIC	5.604	Loss
CAMK_CAMKL_CHK1_CHEK1_ST	Q96T58	SPEN	O14757	CHEK1	S832	S836L	836	Missense	distal	4	no	6.015	6.051	EPSD	TCGA;ICGC;COSMIC	5.604	Up-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q96T58	SPEN	O14757	CHEK1	S832	S830F	830	Missense	proximal	-2	no	6.015	6.304	EPSD	TCGA;ICGC;COSMIC	5.604	Up-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q96T58	SPEN	O14757	CHEK1	S847	E845K	845	Missense	proximal	-2	no	11.313	11.170	EPSD	TCGA;ICGC;COSMIC	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q96T58	SPEN	O14757	CHEK1	S946	V952M	952	Missense	distal	6	no	6.815	6.940	EPSD	TCGA;ICGC;COSMIC	5.604	Up-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q96T58	SPEN	O14757	CHEK1	S946	L945R	945	Missense	proximal	-1	no	6.815	6.716	EPSD	TCGA;ICGC;COSMIC	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q96T58	SPEN	O14757	CHEK1	T1059	A1061V	1061	Missense	proximal	2	no	12.296	11.733	PhosphoSitePlus	TCGA;ICGC;COSMIC	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q96T58	SPEN	O14757	CHEK1	T1059	P1063L	1063	Missense	distal	4	no	12.296	12.192	PhosphoSitePlus	TCGA;ICGC;COSMIC	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q96T58	SPEN	O14757	CHEK1	T1059	T1059I	1059	Missense	central	0	yes	12.296	0.000	PhosphoSitePlus	TCGA;ICGC;COSMIC	5.604	Loss
CAMK_CAMKL_CHK1_CHEK1_ST	Q96T58	SPEN	O14757	CHEK1	T1140	R1137C	1137	Missense	distal	-3	no	5.971	-2.120	EPSD	TCGA;ICGC;COSMIC	5.604	Loss
CAMK_CAMKL_CHK1_CHEK1_ST	Q96T58	SPEN	O14757	CHEK1	S1194	E1190Q	1190	Missense	distal	-4	no	7.605	7.562	EPSD	TCGA;ICGC;COSMIC	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q96T58	SPEN	O14757	CHEK1	S1252	E1256K	1256	Missense	distal	4	no	9.043	9.037	EPSD	TCGA;ICGC;COSMIC	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q96T58	SPEN	O14757	CHEK1	S1252	D1254H	1254	Missense	proximal	2	no	9.043	8.500	EPSD	TCGA;ICGC;COSMIC	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q96T58	SPEN	O14757	CHEK1	S1252	S1248L	1248	Missense	distal	-4	no	9.043	9.095	EPSD	TCGA;ICGC;COSMIC	5.604	Up-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q96T58	SPEN	O14757	CHEK1	S1268	S1268F	1268	Missense	central	0	yes	9.381	0.000	EPSD	TCGA;ICGC;COSMIC	5.604	Loss
CAMK_CAMKL_CHK1_CHEK1_ST	Q96T58	SPEN	O14757	CHEK1	S1268	E1271D	1271	Missense	distal	3	no	9.381	9.478	EPSD	TCGA;ICGC;COSMIC	5.604	Up-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q96T58	SPEN	O14757	CHEK1	S1306	E1305V	1305	Missense	proximal	-1	no	7.820	8.005	EPSD	TCGA;ICGC;COSMIC;CCLE	5.604	Up-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q96T58	SPEN	O14757	CHEK1	S1369	R1366Q	1366	Missense	distal	-3	no	9.734	2.527	EPSD	TCGA;ICGC;COSMIC	5.604	Loss
CAMK_CAMKL_CHK1_CHEK1_ST	Q96T58	SPEN	O14757	CHEK1	S1424	N1429K	1429	Missense	distal	5	no	9.156	9.179	EPSD	TCGA;ICGC;COSMIC	5.604	Up-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q96T58	SPEN	O14757	CHEK1	S1424	E1427Q	1427	Missense	distal	3	no	9.156	8.756	EPSD	TCGA;ICGC;COSMIC	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q96T58	SPEN	O14757	CHEK1	S1424	K1430T	1430	Missense	distal	6	no	9.156	9.467	EPSD	TCGA;ICGC;COSMIC	5.604	Up-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q96T58	SPEN	O14757	CHEK1	T1441	F1434S	1434	Missense	distal	-7	no	5.510	7.242	EPSD	TCGA;ICGC;COSMIC	5.604	Gain
CAMK_CAMKL_CHK1_CHEK1_ST	Q96T58	SPEN	O14757	CHEK1	S1453	R1458C	1458	Missense	distal	5	no	13.331	13.088	EPSD	TCGA;ICGC;COSMIC	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q96T58	SPEN	O14757	CHEK1	S1453	S1457A	1457	Missense	distal	4	no	13.331	13.525	EPSD	TCGA;ICGC;COSMIC	5.604	Up-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q96T58	SPEN	O14757	CHEK1	S1453	A1451T	1451	Missense	proximal	-2	no	13.331	13.471	EPSD	TCGA;ICGC;COSMIC	5.604	Up-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q96T58	SPEN	O14757	CHEK1	S1485	D1484E	1484	Missense	proximal	-1	no	9.113	9.055	EPSD	TCGA;ICGC;COSMIC	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q96T58	SPEN	O14757	CHEK1	S1485	P1489R	1489	Missense	distal	4	no	9.113	9.024	EPSD	TCGA;ICGC;COSMIC	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q96T58	SPEN	O14757	CHEK1	S1485	R1488I	1488	Missense	distal	3	no	9.113	8.741	EPSD	TCGA;ICGC;COSMIC;GDSC;CCLE	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q96T58	SPEN	O14757	CHEK1	T1502	M1495I	1495	Missense	distal	-7	no	7.571	7.329	EPSD	TCGA;ICGC;COSMIC	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q96T58	SPEN	O14757	CHEK1	T1502	D1509N	1509	Missense	distal	7	no	7.571	7.410	EPSD	TCGA;ICGC;COSMIC	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q96T58	SPEN	O14757	CHEK1	T1502	K1497N	1497	Missense	distal	-5	no	7.571	6.678	EPSD	TCGA;ICGC	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q96T58	SPEN	O14757	CHEK1	S1504	D1509N	1509	Missense	distal	5	no	13.048	12.959	EPSD	TCGA;ICGC;COSMIC	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q96T58	SPEN	O14757	CHEK1	S1504	D1510N	1510	Missense	distal	6	no	13.048	13.366	EPSD	TCGA;ICGC;COSMIC	5.604	Up-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q96T58	SPEN	O14757	CHEK1	S1504	K1497N	1497	Missense	distal	-7	no	13.048	11.590	EPSD	TCGA;ICGC	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q96T58	SPEN	O14757	CHEK1	S1566	S1571N	1571	Missense	distal	5	no	5.651	5.649	EPSD	TCGA;ICGC;COSMIC	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q96T58	SPEN	O14757	CHEK1	S2392	S2387N	2387	Missense	distal	-5	no	8.135	8.628	EPSD	TCGA;ICGC;COSMIC	5.604	Up-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q96T58	SPEN	O14757	CHEK1	S2392	Q2386H	2386	Missense	distal	-6	no	8.135	8.162	EPSD	TCGA;ICGC;COSMIC	5.604	Up-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q96T58	SPEN	O14757	CHEK1	S2407	S2400Y	2400	Missense	distal	-7	no	6.767	5.109	EPSD	TCGA;ICGC;COSMIC	5.604	Loss
CAMK_CAMKL_CHK1_CHEK1_ST	Q96T58	SPEN	O14757	CHEK1	S2407	D2401N	2401	Missense	distal	-6	no	6.767	6.980	EPSD	TCGA;ICGC;COSMIC	5.604	Up-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q96T58	SPEN	O14757	CHEK1	S2407	S2411L	2411	Missense	distal	4	no	6.767	6.803	EPSD	TCGA;ICGC;COSMIC	5.604	Up-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q96T58	SPEN	O14757	CHEK1	S2407	S2403R	2403	Missense	distal	-4	no	6.767	7.075	EPSD	TCGA;ICGC;COSMIC	5.604	Up-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q96T58	SPEN	O14757	CHEK1	S2416	S2411L	2411	Missense	distal	-5	no	3.388	6.576	EPSD	TCGA;ICGC;COSMIC	5.604	Gain
CAMK_CAMKL_CHK1_CHEK1_ST	Q96T58	SPEN	O14757	CHEK1	T2423	P2428S	2428	Missense	distal	5	no	6.850	6.932	EPSD	TCGA;ICGC;COSMIC	5.604	Up-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q96T58	SPEN	O14757	CHEK1	T2423	S2426Y	2426	Missense	distal	3	no	6.850	5.622	EPSD	TCGA;ICGC;COSMIC	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q96T58	SPEN	O14757	CHEK1	S3014	A3009G	3009	Missense	distal	-5	no	4.525	7.299	EPSD	TCGA	5.604	Gain
CAMK_CAMKL_CHK1_CHEK1_ST	Q96T58	SPEN	O14757	CHEK1	T3102	I3108M	3108	Missense	distal	6	no	6.301	6.659	EPSD	TCGA;ICGC;COSMIC	5.604	Up-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q96T58	SPEN	O14757	CHEK1	T3139	P3140L	3140	Missense	proximal	1	no	6.682	6.710	EPSD	TCGA;ICGC;COSMIC	5.604	Up-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q96T58	SPEN	O14757	CHEK1	T3139	R3132K	3132	Missense	distal	-7	no	6.682	7.862	EPSD	TCGA;ICGC;COSMIC	5.604	Up-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q9NRM7	LATS2	O14757	CHEK1	T58	M64I	64	Missense	distal	6	no	6.889	6.531	EPSD	TCGA;ICGC;COSMIC	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q9NRM7	LATS2	O14757	CHEK1	T58	D56Y	56	Missense	proximal	-2	no	6.889	6.954	EPSD	TCGA;ICGC;COSMIC	5.604	Up-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q9NRM7	LATS2	O14757	CHEK1	S172	G175R	175	Missense	distal	3	no	6.543	6.628	EPSD	TCGA;ICGC;COSMIC	5.604	Up-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q9NRM7	LATS2	O14757	CHEK1	S172	P166S	166	Missense	distal	-6	no	6.543	6.445	EPSD	TCGA;ICGC;COSMIC	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q9NRM7	LATS2	O14757	CHEK1	S172	T168M	168	Missense	distal	-4	no	6.543	6.738	EPSD	TCGA;ICGC;COSMIC	5.604	Up-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q9NRM7	LATS2	O14757	CHEK1	S274	P280L	280	Missense	distal	6	no	8.401	8.191	EPSD	TCGA;ICGC;COSMIC	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q9NRM7	LATS2	O14757	CHEK1	S408	P414L	414	Missense	distal	6	no	10.512	10.302	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q9NRM7	LATS2	O14757	CHEK1	S528	R525C	525	Missense	distal	-3	no	11.224	3.132	EPSD	TCGA;ICGC;COSMIC;GDSC;CCLE	5.604	Loss
CAMK_CAMKL_CHK1_CHEK1_ST	Q9NRM7	LATS2	O14757	CHEK1	S528	S528L	528	Missense	central	0	yes	11.224	0.000	EPSD	TCGA;ICGC;COSMIC	5.604	Loss
CAMK_CAMKL_CHK1_CHEK1_ST	Q9NRM7	LATS2	O14757	CHEK1	S598	A601T	601	Missense	distal	3	no	6.398	6.160	EPSD	TCGA;ICGC;COSMIC	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q9NRM7	LATS2	O14757	CHEK1	S598	R593C	593	Missense	distal	-5	no	6.398	5.719	EPSD	TCGA;ICGC;COSMIC	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q9NRM7	LATS2	O14757	CHEK1	S835	R832G	832	Missense	distal	-3	no	7.876	0.102	PhosphoSitePlus;EPSD	TCGA;ICGC;COSMIC	5.604	Loss
CAMK_CAMKL_CHK1_CHEK1_ST	Q9NRM7	LATS2	O14757	CHEK1	S835	Q833H	833	Missense	proximal	-2	no	7.876	7.895	PhosphoSitePlus;EPSD	TCGA;ICGC;COSMIC	5.604	Up-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q9NRM7	LATS2	O14757	CHEK1	S835	L841F	841	Missense	distal	6	no	7.876	7.869	PhosphoSitePlus;EPSD	TCGA;ICGC;COSMIC	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q9NRM7	LATS2	O14757	CHEK1	S839	S846F	846	Missense	distal	7	no	5.616	5.186	EPSD	TCGA	5.604	Loss
CAMK_CAMKL_CHK1_CHEK1_ST	Q9NRM7	LATS2	O14757	CHEK1	S839	R832G	832	Missense	distal	-7	no	5.616	5.654	EPSD	TCGA;ICGC;COSMIC	5.604	Up-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q9NRM7	LATS2	O14757	CHEK1	S839	Q833H	833	Missense	distal	-6	no	5.616	5.644	EPSD	TCGA;ICGC;COSMIC	5.604	Up-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q9NRM7	LATS2	O14757	CHEK1	S839	L841F	841	Missense	proximal	2	no	5.616	5.866	EPSD	TCGA;ICGC;COSMIC	5.604	Up-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q5UIP0	RIF1	O14757	CHEK1	S7	L9F	9	Missense	proximal	2	no	9.501	9.751	EPSD	TCGA;ICGC;COSMIC	5.604	Up-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q5UIP0	RIF1	O14757	CHEK1	S7	E14D	14	Missense	distal	7	no	9.501	9.559	EPSD	TCGA;ICGC;COSMIC	5.604	Up-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q5UIP0	RIF1	O14757	CHEK1	S223	E220K	220	Missense	distal	-3	no	2.960	6.222	EPSD	TCGA;ICGC;COSMIC;GDSC;CCLE	5.604	Gain
CAMK_CAMKL_CHK1_CHEK1_ST	Q5UIP0	RIF1	O14757	CHEK1	S401	T394A	394	Missense	distal	-7	no	5.010	6.327	EPSD	TCGA;ICGC;COSMIC	5.604	Gain
CAMK_CAMKL_CHK1_CHEK1_ST	Q5UIP0	RIF1	O14757	CHEK1	S782	R785K	785	Missense	distal	3	no	6.330	6.977	EPSD	TCGA;ICGC;COSMIC	5.604	Up-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q5UIP0	RIF1	O14757	CHEK1	S782	S787L	787	Missense	distal	5	no	6.330	6.087	EPSD	TCGA;ICGC;COSMIC	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q5UIP0	RIF1	O14757	CHEK1	S802	F804C	804	Missense	proximal	2	no	10.559	10.342	EPSD	TCGA	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q5UIP0	RIF1	O14757	CHEK1	S802	K805T	805	Missense	distal	3	no	10.559	9.772	EPSD	TCGA	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q5UIP0	RIF1	O14757	CHEK1	S818	L817P	817	Missense	proximal	-1	no	6.874	7.060	EPSD	TCGA;ICGC;COSMIC	5.604	Up-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q5UIP0	RIF1	O14757	CHEK1	S818	S813Y	813	Missense	distal	-5	no	6.874	6.190	EPSD	TCGA;ICGC;COSMIC	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q5UIP0	RIF1	O14757	CHEK1	S1030	V1035L	1035	Missense	distal	5	no	8.098	7.939	EPSD	TCGA;ICGC;COSMIC	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q5UIP0	RIF1	O14757	CHEK1	S1030	L1026V	1026	Missense	distal	-4	no	8.098	8.346	EPSD	TCGA;ICGC;COSMIC	5.604	Up-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q5UIP0	RIF1	O14757	CHEK1	S1030	K1034Q	1034	Missense	distal	4	no	8.098	8.196	EPSD	TCGA;ICGC;COSMIC	5.604	Up-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q5UIP0	RIF1	O14757	CHEK1	S1030	G1037S	1037	Missense	distal	7	no	8.098	8.000	EPSD	TCGA;ICGC;COSMIC	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q5UIP0	RIF1	O14757	CHEK1	S1089	L1086R	1086	Missense	distal	-3	no	-7.673	10.873	EPSD	TCGA;ICGC;COSMIC	5.604	Gain
CAMK_CAMKL_CHK1_CHEK1_ST	Q5UIP0	RIF1	O14757	CHEK1	T1372	K1376N	1376	Missense	distal	4	no	7.207	7.275	EPSD	TCGA;ICGC;COSMIC	5.604	Up-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q5UIP0	RIF1	O14757	CHEK1	S1418	R1420Q	1420	Missense	proximal	2	no	8.615	9.144	EPSD	TCGA;ICGC;COSMIC	5.604	Up-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q5UIP0	RIF1	O14757	CHEK1	S1418	R1421C	1421	Missense	distal	3	no	8.615	7.668	EPSD	TCGA;ICGC	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q5UIP0	RIF1	O14757	CHEK1	S1422	R1420Q	1420	Missense	proximal	-2	no	7.244	7.290	EPSD	TCGA;ICGC;COSMIC	5.604	Up-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q5UIP0	RIF1	O14757	CHEK1	S1422	R1421C	1421	Missense	proximal	-1	no	7.244	7.279	EPSD	TCGA;ICGC	5.604	Up-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q5UIP0	RIF1	O14757	CHEK1	S1437	R1444H	1444	Missense	distal	7	no	7.019	6.726	EPSD	TCGA;ICGC;COSMIC	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q5UIP0	RIF1	O14757	CHEK1	S1437	S1431N	1431	Missense	distal	-6	no	7.019	7.060	EPSD	TCGA;ICGC;COSMIC	5.604	Up-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q5UIP0	RIF1	O14757	CHEK1	S1437	D1433Y	1433	Missense	distal	-4	no	7.019	6.472	EPSD	TCGA;ICGC;COSMIC	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q5UIP0	RIF1	O14757	CHEK1	S1437	N1436T	1436	Missense	proximal	-1	no	7.019	7.005	EPSD	TCGA;ICGC;COSMIC	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q5UIP0	RIF1	O14757	CHEK1	T1534	R1535W	1535	Missense	proximal	1	no	11.148	11.118	EPSD	TCGA;ICGC;COSMIC	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q5UIP0	RIF1	O14757	CHEK1	T1538	R1535W	1535	Missense	distal	-3	no	7.580	-26.023	EPSD	TCGA;ICGC;COSMIC	5.604	Loss
CAMK_CAMKL_CHK1_CHEK1_ST	Q5UIP0	RIF1	O14757	CHEK1	T1538	S1542Y	1542	Missense	distal	4	no	7.580	7.754	EPSD	TCGA	5.604	Up-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q5UIP0	RIF1	O14757	CHEK1	S1542	R1535W	1535	Missense	distal	-7	no	5.816	4.270	EPSD	TCGA;ICGC;COSMIC	5.604	Loss
CAMK_CAMKL_CHK1_CHEK1_ST	Q5UIP0	RIF1	O14757	CHEK1	S1542	S1542Y	1542	Missense	central	0	yes	5.816	0.000	EPSD	TCGA	5.604	Loss
CAMK_CAMKL_CHK1_CHEK1_ST	Q5UIP0	RIF1	O14757	CHEK1	T1656	K1653N	1653	Missense	distal	-3	no	6.845	0.303	EPSD	TCGA;ICGC;COSMIC	5.604	Loss
CAMK_CAMKL_CHK1_CHEK1_ST	Q5UIP0	RIF1	O14757	CHEK1	S1688	D1690H	1690	Missense	proximal	2	no	8.193	7.650	EPSD	TCGA;ICGC;COSMIC	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q5UIP0	RIF1	O14757	CHEK1	T1822	K1819R	1819	Missense	distal	-3	no	7.091	10.917	EPSD	TCGA;ICGC;COSMIC	5.604	Up-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q5UIP0	RIF1	O14757	CHEK1	T1822	S1818L	1818	Missense	distal	-4	no	7.091	7.143	EPSD	TCGA;ICGC;COSMIC	5.604	Up-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q5UIP0	RIF1	O14757	CHEK1	T1822	S1826Y	1826	Missense	distal	4	no	7.091	7.265	EPSD	TCGA;ICGC	5.604	Up-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q5UIP0	RIF1	O14757	CHEK1	S1826	K1819R	1819	Missense	distal	-7	no	6.399	5.220	EPSD	TCGA;ICGC;COSMIC	5.604	Loss
CAMK_CAMKL_CHK1_CHEK1_ST	Q5UIP0	RIF1	O14757	CHEK1	S1826	S1826Y	1826	Missense	central	0	yes	6.399	0.000	EPSD	TCGA;ICGC	5.604	Loss
CAMK_CAMKL_CHK1_CHEK1_ST	Q5UIP0	RIF1	O14757	CHEK1	S1826	V1832A	1832	Missense	distal	6	no	6.399	6.512	EPSD	TCGA;ICGC;COSMIC	5.604	Up-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q5UIP0	RIF1	O14757	CHEK1	S1952	N1949H	1949	Missense	distal	-3	no	3.203	7.762	EPSD	TCGA;ICGC	5.604	Gain
CAMK_CAMKL_CHK1_CHEK1_ST	Q5UIP0	RIF1	O14757	CHEK1	S2205	R2203C	2203	Missense	proximal	-2	no	12.302	12.251	PhosphoSitePlus	TCGA;ICGC;COSMIC	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q5UIP0	RIF1	O14757	CHEK1	S2205	I2210L	2210	Missense	distal	5	no	12.302	12.202	PhosphoSitePlus	TCGA;ICGC	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q5UIP0	RIF1	O14757	CHEK1	S2205	R2202C	2202	Missense	distal	-3	no	12.302	4.211	PhosphoSitePlus	TCGA;ICGC;COSMIC	5.604	Loss
CAMK_CAMKL_CHK1_CHEK1_ST	Q5UIP0	RIF1	O14757	CHEK1	S2205	I2210T	2210	Missense	distal	5	no	12.302	12.223	PhosphoSitePlus	TCGA;ICGC;COSMIC	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q5UIP0	RIF1	O14757	CHEK1	S2205	R2203H	2203	Missense	proximal	-2	no	12.302	12.367	PhosphoSitePlus	TCGA;ICGC	5.604	Up-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q5UIP0	RIF1	O14757	CHEK1	S2224	S2228Y	2228	Missense	distal	4	no	8.876	9.050	EPSD	TCGA;ICGC;COSMIC	5.604	Up-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q5UIP0	RIF1	O14757	CHEK1	S2224	R2222W	2222	Missense	proximal	-2	no	8.876	8.997	EPSD	TCGA;ICGC;COSMIC;CCLE	5.604	Up-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q5UIP0	RIF1	O14757	CHEK1	S2230	S2228Y	2228	Missense	proximal	-2	no	9.819	9.931	EPSD	TCGA;ICGC;COSMIC	5.604	Up-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q5UIP0	RIF1	O14757	CHEK1	S2230	S2233R	2233	Missense	distal	3	no	9.819	9.816	EPSD	TCGA;ICGC;COSMIC	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q5UIP0	RIF1	O14757	CHEK1	S2230	S2234Y	2234	Missense	distal	4	no	9.819	9.993	EPSD	TCGA;ICGC	5.604	Up-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q5UIP0	RIF1	O14757	CHEK1	S2393	L2399P	2399	Missense	distal	6	no	6.016	6.226	EPSD	TCGA;COSMIC	5.604	Up-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q5UIP0	RIF1	O14757	CHEK1	S2401	L2399P	2399	Missense	proximal	-2	no	6.579	6.758	EPSD	TCGA;COSMIC	5.604	Up-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q5UIP0	RIF1	O14757	CHEK1	S2465	L2459I	2459	Missense	distal	-6	no	6.321	6.295	EPSD	TCGA;COSMIC	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q96GD4	AURKB	O14757	CHEK1	T73	E78Q	78	Missense	distal	5	no	10.670	10.557	EPSD	TCGA;ICGC;COSMIC	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q96GD4	AURKB	O14757	CHEK1	T232	G235D	235	Missense	distal	3	no	5.281	6.926	EPSD	TCGA;COSMIC	5.604	Gain
CAMK_CAMKL_CHK1_CHEK1_ST	Q96GD4	AURKB	O14757	CHEK1	S313	S313L	313	Missense	central	0	yes	8.877	0.000	EPSD	TCGA;COSMIC	5.604	Loss
CAMK_CAMKL_CHK1_CHEK1_ST	Q96GD4	AURKB	O14757	CHEK1	S331	P336L	336	Missense	distal	5	no	7.984	7.822	PhosphoSitePlus	TCGA;COSMIC	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q96GD4	AURKB	O14757	CHEK1	S331	R332Q	332	Missense	proximal	1	no	7.984	7.993	PhosphoSitePlus	TCGA;COSMIC	5.604	Up-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q9NXE8	CWC25	O14757	CHEK1	S195	S195N	195	Missense	central	0	yes	9.059	0.000	EPSD	TCGA	5.604	Loss
CAMK_CAMKL_CHK1_CHEK1_ST	Q9NXE8	CWC25	O14757	CHEK1	S195	S194L	194	Missense	proximal	-1	no	9.059	9.320	EPSD	TCGA	5.604	Up-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q9NXE8	CWC25	O14757	CHEK1	S195	E202G	202	Missense	distal	7	no	9.059	8.825	EPSD	TCGA	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q9NXE8	CWC25	O14757	CHEK1	S201	S195N	195	Missense	distal	-6	no	8.239	8.280	EPSD	TCGA	5.604	Up-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q9NXE8	CWC25	O14757	CHEK1	S201	S194L	194	Missense	distal	-7	no	8.239	7.355	EPSD	TCGA	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q9NXE8	CWC25	O14757	CHEK1	S201	E202G	202	Missense	proximal	1	no	8.239	8.156	EPSD	TCGA	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q9NXE8	CWC25	O14757	CHEK1	S201	A207T	207	Missense	distal	6	no	8.239	8.162	EPSD	TCGA	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q9NXE8	CWC25	O14757	CHEK1	T245	G242R	242	Missense	distal	-3	no	4.562	12.337	EPSD	TCGA	5.604	Gain
CAMK_CAMKL_CHK1_CHEK1_ST	Q9NXE8	CWC25	O14757	CHEK1	S260	M254I	254	Missense	distal	-6	no	6.272	6.208	EPSD	TCGA	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q9NXE8	CWC25	O14757	CHEK1	S260	G253R	253	Missense	distal	-7	no	6.272	6.233	EPSD	TCGA	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q9NXE8	CWC25	O14757	CHEK1	S260	R259S	259	Missense	proximal	-1	no	6.272	6.110	EPSD	TCGA	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q9NXE8	CWC25	O14757	CHEK1	S260	M254L	254	Missense	distal	-6	no	6.272	6.234	EPSD	TCGA	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q9NXE8	CWC25	O14757	CHEK1	S262	R259S	259	Missense	distal	-3	no	10.536	0.840	EPSD	TCGA	5.604	Loss
CAMK_CAMKL_CHK1_CHEK1_ST	Q9NXE8	CWC25	O14757	CHEK1	S264	R259S	259	Missense	distal	-5	no	11.550	11.338	EPSD	TCGA	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q9NXE8	CWC25	O14757	CHEK1	S288	S286F	286	Missense	proximal	-2	no	6.871	7.161	EPSD	TCGA	5.604	Up-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q9NXE8	CWC25	O14757	CHEK1	S288	R292K	292	Missense	distal	4	no	6.871	6.773	EPSD	TCGA	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q9NXE8	CWC25	O14757	CHEK1	S288	S288F	288	Missense	central	0	yes	6.871	0.000	EPSD	TCGA	5.604	Loss
CAMK_CAMKL_CHK1_CHEK1_ST	Q9NXE8	CWC25	O14757	CHEK1	S288	R287Q	287	Missense	proximal	-1	no	6.871	6.886	EPSD	TCGA	5.604	Up-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q9NXE8	CWC25	O14757	CHEK1	S295	R292K	292	Missense	distal	-3	no	8.612	4.786	EPSD	TCGA	5.604	Loss
CAMK_CAMKL_CHK1_CHEK1_ST	Q9NXE8	CWC25	O14757	CHEK1	S295	S288F	288	Missense	distal	-7	no	8.612	6.880	EPSD	TCGA	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q9NXE8	CWC25	O14757	CHEK1	S295	P296L	296	Missense	proximal	1	no	8.612	8.640	EPSD	TCGA	5.604	Up-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q9NXE8	CWC25	O14757	CHEK1	T311	R315M	315	Missense	distal	4	no	10.509	10.569	EPSD	TCGA	5.604	Up-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q9NXE8	CWC25	O14757	CHEK1	T311	S304F	304	Missense	distal	-7	no	10.509	8.777	EPSD	TCGA	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q9NXE8	CWC25	O14757	CHEK1	S318	R315M	315	Missense	distal	-3	no	9.670	4.521	EPSD	TCGA	5.604	Loss
CAMK_CAMKL_CHK1_CHEK1_ST	Q9NXE8	CWC25	O14757	CHEK1	S337	E340Q	340	Missense	distal	3	no	9.505	9.104	PhosphoSitePlus	TCGA	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q9NXE8	CWC25	O14757	CHEK1	S337	R343Q	343	Missense	distal	6	no	9.505	9.498	PhosphoSitePlus	TCGA;ICGC;GDSC;CCLE	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q9NXE8	CWC25	O14757	CHEK1	S337	S337F	337	Missense	central	0	yes	9.505	0.000	PhosphoSitePlus	TCGA	5.604	Loss
CAMK_CAMKL_CHK1_CHEK1_ST	Q96PK6	RBM14	O14757	CHEK1	S147	V144G	144	Missense	distal	-3	no	5.557	6.246	EPSD	TCGA;ICGC;COSMIC	5.604	Gain
CAMK_CAMKL_CHK1_CHEK1_ST	Q96PK6	RBM14	O14757	CHEK1	S147	R141H	141	Missense	distal	-6	no	5.557	5.666	EPSD	TCGA;ICGC;COSMIC;CCLE	5.604	Gain
CAMK_CAMKL_CHK1_CHEK1_ST	Q96PK6	RBM14	O14757	CHEK1	T206	R203H	203	Missense	distal	-3	no	7.813	2.004	EPSD	TCGA;ICGC;COSMIC	5.604	Loss
CAMK_CAMKL_CHK1_CHEK1_ST	Q96PK6	RBM14	O14757	CHEK1	S215	R214C	214	Missense	proximal	-1	no	10.265	10.300	EPSD	TCGA;ICGC;COSMIC	5.604	Up-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q96PK6	RBM14	O14757	CHEK1	S294	S300Y	300	Missense	distal	6	no	5.932	6.674	EPSD	TCGA;ICGC	5.604	Up-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q96PK6	RBM14	O14757	CHEK1	T518	A513T	513	Missense	distal	-5	no	1.860	5.721	EPSD	TCGA;ICGC;COSMIC	5.604	Gain
CAMK_CAMKL_CHK1_CHEK1_ST	Q96PK6	RBM14	O14757	CHEK1	S520	R517H	517	Missense	distal	-3	no	10.194	4.385	EPSD	TCGA;ICGC;COSMIC;GDSC;CCLE	5.604	Loss
CAMK_CAMKL_CHK1_CHEK1_ST	Q96PK6	RBM14	O14757	CHEK1	S520	A513T	513	Missense	distal	-7	no	10.194	8.877	EPSD	TCGA;ICGC;COSMIC	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q96PK6	RBM14	O14757	CHEK1	S520	T518S	518	Missense	proximal	-2	no	10.194	9.940	EPSD	TCGA;ICGC;COSMIC	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q96PK6	RBM14	O14757	CHEK1	S560	S560F	560	Missense	central	0	yes	7.634	0.000	EPSD	TCGA;ICGC;COSMIC	5.604	Loss
CAMK_CAMKL_CHK1_CHEK1_ST	Q96PK6	RBM14	O14757	CHEK1	S560	P554S	554	Missense	distal	-6	no	7.634	7.536	EPSD	TCGA;ICGC;COSMIC	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q96PK6	RBM14	O14757	CHEK1	S618	S623L	623	Missense	distal	5	no	7.059	6.815	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q96PK6	RBM14	O14757	CHEK1	S618	R625C	625	Missense	distal	7	no	7.059	6.653	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q96PK6	RBM14	O14757	CHEK1	S627	S623L	623	Missense	distal	-4	no	7.028	7.080	PhosphoSitePlus;EPSD	TCGA;ICGC;COSMIC	5.604	Up-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q96PK6	RBM14	O14757	CHEK1	S627	R625C	625	Missense	proximal	-2	no	7.028	6.976	PhosphoSitePlus;EPSD	TCGA;ICGC;COSMIC	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q96PK6	RBM14	O14757	CHEK1	S627	R626H	626	Missense	proximal	-1	no	7.028	7.153	PhosphoSitePlus;EPSD	TCGA;ICGC;COSMIC;GDSC;CCLE	5.604	Up-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q96PK6	RBM14	O14757	CHEK1	T629	R636C	636	Missense	distal	7	no	10.671	10.265	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q96PK6	RBM14	O14757	CHEK1	T629	S623L	623	Missense	distal	-6	no	10.671	10.695	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	5.604	Up-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q96PK6	RBM14	O14757	CHEK1	T629	R625C	625	Missense	distal	-4	no	10.671	10.297	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q96PK6	RBM14	O14757	CHEK1	T629	R626H	626	Missense	distal	-3	no	10.671	4.862	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC;GDSC;CCLE	5.604	Loss
CAMK_CAMKL_CHK1_CHEK1_ST	Q13907	IDI1	O14757	CHEK1	S55	V56L	56	Missense	proximal	1	no	14.294	14.291	PhosphoSitePlus	TCGA;ICGC;COSMIC	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q13907	IDI1	O14757	CHEK1	S55	L49I	49	Missense	distal	-6	no	14.294	14.268	PhosphoSitePlus	TCGA;ICGC;COSMIC	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	O14757	CHEK1	O14757	CHEK1	T378	R379Q	379	Missense	proximal	1	no	6.209	6.218	PhosphoSitePlus	TCGA;ICGC;COSMIC	5.604	Up-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q9H8G2	CAAP1	O14757	CHEK1	T90	S96L	96	Missense	distal	6	no	5.330	5.740	EPSD	TCGA;ICGC;COSMIC	5.604	Gain
CAMK_CAMKL_CHK1_CHEK1_ST	Q9Y520	PRRC2C	O14757	CHEK1	S191	S189L	189	Missense	proximal	-2	no	7.641	7.746	EPSD	TCGA;COSMIC	5.604	Up-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q9Y520	PRRC2C	O14757	CHEK1	S208	D212Y	212	Missense	distal	4	no	6.325	6.449	EPSD	TCGA;COSMIC	5.604	Up-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q9Y520	PRRC2C	O14757	CHEK1	S395	T402P	402	Missense	distal	7	no	5.511	5.633	EPSD	TCGA;COSMIC	5.604	Gain
CAMK_CAMKL_CHK1_CHEK1_ST	Q9Y520	PRRC2C	O14757	CHEK1	S403	R400C	400	Missense	distal	-3	no	8.824	0.733	EPSD	TCGA;COSMIC	5.604	Loss
CAMK_CAMKL_CHK1_CHEK1_ST	Q9Y520	PRRC2C	O14757	CHEK1	S403	T402P	402	Missense	proximal	-1	no	8.824	9.067	EPSD	TCGA;COSMIC	5.604	Up-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q9Y520	PRRC2C	O14757	CHEK1	S453	R449Q	449	Missense	distal	-4	no	8.461	8.621	EPSD	TCGA;COSMIC	5.604	Up-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q9Y520	PRRC2C	O14757	CHEK1	S633	R635C	635	Missense	proximal	2	no	5.644	5.378	EPSD	TCGA;COSMIC	5.604	Loss
CAMK_CAMKL_CHK1_CHEK1_ST	Q9Y520	PRRC2C	O14757	CHEK1	S633	R635H	635	Missense	proximal	2	no	5.644	5.663	EPSD	TCGA;COSMIC	5.604	Up-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q9Y520	PRRC2C	O14757	CHEK1	S633	V627I	627	Missense	distal	-6	no	5.644	5.631	EPSD	TCGA;COSMIC;CCLE	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q9Y520	PRRC2C	O14757	CHEK1	S785	S782R	782	Missense	distal	-3	no	-0.461	9.235	EPSD	TCGA	5.604	Gain
CAMK_CAMKL_CHK1_CHEK1_ST	Q9Y520	PRRC2C	O14757	CHEK1	T821	Q818R	818	Missense	distal	-3	no	1.458	8.664	EPSD	TCGA;COSMIC	5.604	Gain
CAMK_CAMKL_CHK1_CHEK1_ST	Q9Y520	PRRC2C	O14757	CHEK1	T826	P829R	829	Missense	distal	3	no	6.156	5.824	EPSD	TCGA;COSMIC	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q9Y520	PRRC2C	O14757	CHEK1	T826	D831Y	831	Missense	distal	5	no	6.156	5.615	EPSD	TCGA	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q9Y520	PRRC2C	O14757	CHEK1	S867	E865Q	865	Missense	proximal	-2	no	9.602	9.687	EPSD	TCGA;COSMIC	5.604	Up-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q9Y520	PRRC2C	O14757	CHEK1	S867	A869T	869	Missense	proximal	2	no	9.602	8.754	EPSD	TCGA;COSMIC	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q9Y520	PRRC2C	O14757	CHEK1	S867	E868D	868	Missense	proximal	1	no	9.602	9.607	EPSD	TCGA;COSMIC	5.604	Up-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q9Y520	PRRC2C	O14757	CHEK1	S867	F874C	874	Missense	distal	7	no	9.602	9.719	EPSD	TCGA	5.604	Up-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q9Y520	PRRC2C	O14757	CHEK1	S876	A869T	869	Missense	distal	-7	no	6.991	5.674	EPSD	TCGA;COSMIC	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q9Y520	PRRC2C	O14757	CHEK1	S876	F874C	874	Missense	proximal	-2	no	6.991	6.749	EPSD	TCGA	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q9Y520	PRRC2C	O14757	CHEK1	S905	R911W	911	Missense	distal	6	no	7.115	7.582	EPSD	TCGA;COSMIC	5.604	Up-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q9Y520	PRRC2C	O14757	CHEK1	S924	V925I	925	Missense	proximal	1	no	8.986	8.956	EPSD	TCGA	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q9Y520	PRRC2C	O14757	CHEK1	S924	G928A	928	Missense	distal	4	no	8.986	9.112	EPSD	TCGA;COSMIC	5.604	Up-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q9Y520	PRRC2C	O14757	CHEK1	S924	P919L	919	Missense	distal	-5	no	8.986	13.692	EPSD	TCGA;COSMIC	5.604	Up-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q9Y520	PRRC2C	O14757	CHEK1	S924	S926F	926	Missense	proximal	2	no	8.986	8.841	EPSD	TCGA;COSMIC	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q9Y520	PRRC2C	O14757	CHEK1	S924	R921Q	921	Missense	distal	-3	no	8.986	1.779	EPSD	TCGA;COSMIC	5.604	Loss
CAMK_CAMKL_CHK1_CHEK1_ST	Q9Y520	PRRC2C	O14757	CHEK1	S926	V925I	925	Missense	proximal	-1	no	9.532	9.395	EPSD	TCGA	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q9Y520	PRRC2C	O14757	CHEK1	S926	G928A	928	Missense	proximal	2	no	9.532	10.054	EPSD	TCGA;COSMIC	5.604	Up-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q9Y520	PRRC2C	O14757	CHEK1	S926	P919L	919	Missense	distal	-7	no	9.532	9.318	EPSD	TCGA;COSMIC	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q9Y520	PRRC2C	O14757	CHEK1	S926	S926F	926	Missense	central	0	yes	9.532	0.000	EPSD	TCGA;COSMIC	5.604	Loss
CAMK_CAMKL_CHK1_CHEK1_ST	Q9Y520	PRRC2C	O14757	CHEK1	S926	R921Q	921	Missense	distal	-5	no	9.532	9.136	EPSD	TCGA;COSMIC	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q9Y520	PRRC2C	O14757	CHEK1	S999	N1006T	1006	Missense	distal	7	no	6.359	6.063	EPSD	TCGA;COSMIC	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q9Y520	PRRC2C	O14757	CHEK1	S999	R992C	992	Missense	distal	-7	no	6.359	5.631	EPSD	TCGA;COSMIC	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q9Y520	PRRC2C	O14757	CHEK1	S1155	K1161T	1161	Missense	distal	6	no	7.537	7.847	EPSD	TCGA;COSMIC	5.604	Up-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q9Y520	PRRC2C	O14757	CHEK1	S1155	R1152Q	1152	Missense	distal	-3	no	7.537	0.330	EPSD	TCGA;COSMIC	5.604	Loss
CAMK_CAMKL_CHK1_CHEK1_ST	Q9Y520	PRRC2C	O14757	CHEK1	S1155	E1149V	1149	Missense	distal	-6	no	7.537	7.670	EPSD	TCGA;COSMIC	5.604	Up-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q9Y520	PRRC2C	O14757	CHEK1	T1215	R1216Q	1216	Missense	proximal	1	no	9.178	9.187	EPSD	TCGA;COSMIC	5.604	Up-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q9Y520	PRRC2C	O14757	CHEK1	S1242	E1241K	1241	Missense	proximal	-1	no	7.926	7.868	EPSD	TCGA;COSMIC	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q9Y520	PRRC2C	O14757	CHEK1	S1242	S1246C	1246	Missense	distal	4	no	7.926	8.080	EPSD	TCGA;COSMIC	5.604	Up-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q9Y520	PRRC2C	O14757	CHEK1	S1242	R1239Q	1239	Missense	distal	-3	no	7.926	0.719	EPSD	TCGA;COSMIC	5.604	Loss
CAMK_CAMKL_CHK1_CHEK1_ST	Q9Y520	PRRC2C	O14757	CHEK1	S1242	S1242C	1242	Missense	central	0	yes	7.926	0.000	EPSD	TCGA;COSMIC	5.604	Loss
CAMK_CAMKL_CHK1_CHEK1_ST	Q9Y520	PRRC2C	O14757	CHEK1	S1248	E1241K	1241	Missense	distal	-7	no	7.198	7.895	EPSD	TCGA;COSMIC	5.604	Up-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q9Y520	PRRC2C	O14757	CHEK1	S1248	S1246C	1246	Missense	proximal	-2	no	7.198	7.245	EPSD	TCGA;COSMIC	5.604	Up-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q9Y520	PRRC2C	O14757	CHEK1	S1248	S1242C	1242	Missense	distal	-6	no	7.198	7.233	EPSD	TCGA;COSMIC	5.604	Up-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q9Y520	PRRC2C	O14757	CHEK1	T1364	S1363Y	1363	Missense	proximal	-1	no	6.899	7.227	EPSD	TCGA;COSMIC	5.604	Up-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q9Y520	PRRC2C	O14757	CHEK1	S1544	Q1546R	1546	Missense	proximal	2	no	9.518	8.989	EPSD	TCGA;COSMIC	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q9Y520	PRRC2C	O14757	CHEK1	S1568	P1561H	1561	Missense	distal	-7	no	9.330	9.681	EPSD	TCGA;COSMIC	5.604	Up-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q9Y520	PRRC2C	O14757	CHEK1	S1568	R1565S	1565	Missense	distal	-3	no	9.330	-0.366	EPSD	TCGA;COSMIC	5.604	Loss
CAMK_CAMKL_CHK1_CHEK1_ST	Q9Y520	PRRC2C	O14757	CHEK1	T1625	K1619N	1619	Missense	distal	-6	no	7.071	7.203	EPSD	TCGA;COSMIC	5.604	Up-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q9Y520	PRRC2C	O14757	CHEK1	T1625	D1631Y	1631	Missense	distal	6	no	7.071	7.996	EPSD	TCGA;COSMIC	5.604	Up-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q9Y520	PRRC2C	O14757	CHEK1	T1625	R1629I	1629	Missense	distal	4	no	7.071	7.072	EPSD	TCGA	5.604	Up-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q9Y520	PRRC2C	O14757	CHEK1	S1962	Q1964E	1964	Missense	proximal	2	no	7.933	8.048	EPSD	TCGA;COSMIC	5.604	Up-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q9Y520	PRRC2C	O14757	CHEK1	S2105	E2108Q	2108	Missense	distal	3	no	6.011	5.611	EPSD	TCGA	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q9Y520	PRRC2C	O14757	CHEK1	S2122	R2126I	2126	Missense	distal	4	no	9.468	9.469	EPSD	TCGA	5.604	Up-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q9Y520	PRRC2C	O14757	CHEK1	S2506	L2501I	2501	Missense	distal	-5	no	6.287	4.256	EPSD	TCGA;COSMIC	5.604	Loss
CAMK_CAMKL_CHK1_CHEK1_ST	Q9Y520	PRRC2C	O14757	CHEK1	T2682	A2677T	2677	Missense	distal	-5	no	3.542	7.402	EPSD	TCGA;COSMIC	5.604	Gain
CAMK_CAMKL_CHK1_CHEK1_ST	Q9Y520	PRRC2C	O14757	CHEK1	S2692	N2696H	2696	Missense	distal	4	no	8.173	8.365	EPSD	TCGA;COSMIC	5.604	Up-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q9NS23	RASSF1	O14757	CHEK1	S179	V175M	175	Missense	distal	-4	no	12.253	12.097	EPSD	TCGA;COSMIC	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q9NS23	RASSF1	O14757	CHEK1	S188	R194W	194	Missense	distal	6	no	9.034	9.501	EPSD	TCGA	5.604	Up-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q9NS23	RASSF1	O14757	CHEK1	S201	R205C	205	Missense	distal	4	no	6.475	6.579	EPSD	TCGA;COSMIC	5.604	Up-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q9NS23	RASSF1	O14757	CHEK1	S201	V202A	202	Missense	proximal	1	no	6.475	6.500	EPSD	TCGA;COSMIC	5.604	Up-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q9NS23	RASSF1	O14757	CHEK1	S201	R194W	194	Missense	distal	-7	no	6.475	4.930	EPSD	TCGA	5.604	Loss
CAMK_CAMKL_CHK1_CHEK1_ST	Q9NS23	RASSF1	O14757	CHEK1	T206	R205C	205	Missense	proximal	-1	no	5.700	5.735	EPSD	TCGA;COSMIC	5.604	Up-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q9NS23	RASSF1	O14757	CHEK1	T206	V202A	202	Missense	distal	-4	no	5.700	5.779	EPSD	TCGA;COSMIC	5.604	Up-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	O75151	PHF2	O14757	CHEK1	T496	T493A	493	Missense	distal	-3	no	-7.297	6.561	EPSD	TCGA;ICGC;COSMIC;CCLE	5.604	Gain
CAMK_CAMKL_CHK1_CHEK1_ST	O75151	PHF2	O14757	CHEK1	T654	A661T	661	Missense	distal	7	no	6.116	6.000	EPSD	TCGA;ICGC;COSMIC	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	O75151	PHF2	O14757	CHEK1	S705	P700L	700	Missense	distal	-5	no	5.433	10.140	EPSD	TCGA;ICGC;COSMIC	5.604	Gain
CAMK_CAMKL_CHK1_CHEK1_ST	O75151	PHF2	O14757	CHEK1	T719	T716M	716	Missense	distal	-3	no	-8.725	6.695	EPSD	TCGA;ICGC;COSMIC	5.604	Gain
CAMK_CAMKL_CHK1_CHEK1_ST	O75151	PHF2	O14757	CHEK1	S771	L768R	768	Missense	distal	-3	no	-7.874	10.672	EPSD	TCGA;ICGC;COSMIC	5.604	Gain
CAMK_CAMKL_CHK1_CHEK1_ST	O75151	PHF2	O14757	CHEK1	S899	K894N	894	Missense	distal	-5	no	10.805	9.911	EPSD	TCGA;COSMIC	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	O75151	PHF2	O14757	CHEK1	S899	P903S	903	Missense	distal	4	no	10.805	10.665	EPSD	TCGA;COSMIC	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	O75151	PHF2	O14757	CHEK1	S899	P903L	903	Missense	distal	4	no	10.805	10.701	EPSD	TCGA;COSMIC	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	O75151	PHF2	O14757	CHEK1	S899	R896M	896	Missense	distal	-3	no	10.805	5.656	EPSD	TCGA;COSMIC	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	O75151	PHF2	O14757	CHEK1	S899	S893L	893	Missense	distal	-6	no	10.805	10.829	EPSD	TCGA	5.604	Up-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	O75151	PHF2	O14757	CHEK1	S929	R922C	922	Missense	distal	-7	no	8.732	8.004	PhosphoSitePlus	TCGA	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	O75151	PHF2	O14757	CHEK1	S929	E923D	923	Missense	distal	-6	no	8.732	8.681	PhosphoSitePlus	TCGA;COSMIC	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	O75151	PHF2	O14757	CHEK1	S929	A935V	935	Missense	distal	6	no	8.732	8.619	PhosphoSitePlus	TCGA;COSMIC	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	O75151	PHF2	O14757	CHEK1	S1058	T1064I	1064	Missense	distal	6	no	6.255	5.987	EPSD	TCGA	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	P52272	HNRNPM	O14757	CHEK1	S86	Q85R	85	Missense	proximal	-1	no	7.337	7.322	EPSD	TCGA;ICGC;COSMIC	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	P52272	HNRNPM	O14757	CHEK1	T99	V101M	101	Missense	proximal	2	no	5.453	5.632	EPSD	TCGA;ICGC;COSMIC	5.604	Gain
CAMK_CAMKL_CHK1_CHEK1_ST	P52272	HNRNPM	O14757	CHEK1	S136	N133K	133	Missense	distal	-3	no	1.526	8.069	EPSD	TCGA;ICGC;COSMIC	5.604	Gain
CAMK_CAMKL_CHK1_CHEK1_ST	P52272	HNRNPM	O14757	CHEK1	S204	G203V	203	Missense	proximal	-1	no	7.595	7.672	EPSD	TCGA;ICGC;COSMIC	5.604	Up-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	P52272	HNRNPM	O14757	CHEK1	S204	R201G	201	Missense	distal	-3	no	7.595	-0.180	EPSD	TCGA;ICGC;COSMIC	5.604	Loss
CAMK_CAMKL_CHK1_CHEK1_ST	P52272	HNRNPM	O14757	CHEK1	S225	S225N	225	Missense	central	0	yes	7.770	0.000	EPSD	TCGA;ICGC;COSMIC	5.604	Loss
CAMK_CAMKL_CHK1_CHEK1_ST	P52272	HNRNPM	O14757	CHEK1	S365	G366R	366	Missense	proximal	1	no	10.196	10.204	EPSD	TCGA;ICGC;COSMIC	5.604	Up-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	P52272	HNRNPM	O14757	CHEK1	S365	R362Q	362	Missense	distal	-3	no	10.196	2.989	EPSD	TCGA;ICGC;COSMIC	5.604	Loss
CAMK_CAMKL_CHK1_CHEK1_ST	P52272	HNRNPM	O14757	CHEK1	S432	R436H	436	Missense	distal	4	no	8.821	8.982	PhosphoSitePlus	TCGA;COSMIC	5.604	Up-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	P52272	HNRNPM	O14757	CHEK1	S432	E433K	433	Missense	proximal	1	no	8.821	8.747	PhosphoSitePlus	TCGA;COSMIC	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	P52272	HNRNPM	O14757	CHEK1	S432	G431D	431	Missense	proximal	-1	no	8.821	8.772	PhosphoSitePlus	TCGA;ICGC;COSMIC	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	P52272	HNRNPM	O14757	CHEK1	S432	R429C	429	Missense	distal	-3	no	8.821	0.730	PhosphoSitePlus	TCGA;ICGC;COSMIC	5.604	Loss
CAMK_CAMKL_CHK1_CHEK1_ST	P52272	HNRNPM	O14757	CHEK1	S432	R436C	436	Missense	distal	4	no	8.821	8.925	PhosphoSitePlus	TCGA;COSMIC	5.604	Up-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	P52272	HNRNPM	O14757	CHEK1	S446	M450R	450	Missense	distal	4	no	8.749	8.689	EPSD	TCGA	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	P52272	HNRNPM	O14757	CHEK1	S446	M444V	444	Missense	proximal	-2	no	8.749	8.798	EPSD	TCGA;COSMIC	5.604	Up-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	P52272	HNRNPM	O14757	CHEK1	S446	R449L	449	Missense	distal	3	no	8.749	8.317	EPSD	TCGA;COSMIC	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	P52272	HNRNPM	O14757	CHEK1	S446	R443C	443	Missense	distal	-3	no	8.749	0.657	EPSD	TCGA	5.604	Loss
CAMK_CAMKL_CHK1_CHEK1_ST	P52272	HNRNPM	O14757	CHEK1	S446	R449C	449	Missense	distal	3	no	8.749	7.801	EPSD	TCGA;COSMIC	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	P52272	HNRNPM	O14757	CHEK1	S452	M450R	450	Missense	proximal	-2	no	10.492	10.449	EPSD	TCGA	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	P52272	HNRNPM	O14757	CHEK1	S452	R449L	449	Missense	distal	-3	no	10.492	-8.054	EPSD	TCGA;COSMIC	5.604	Loss
CAMK_CAMKL_CHK1_CHEK1_ST	P52272	HNRNPM	O14757	CHEK1	S452	M457V	457	Missense	distal	5	no	10.492	10.519	EPSD	TCGA;COSMIC	5.604	Up-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	P52272	HNRNPM	O14757	CHEK1	S452	R449C	449	Missense	distal	-3	no	10.492	2.401	EPSD	TCGA;COSMIC	5.604	Loss
CAMK_CAMKL_CHK1_CHEK1_ST	P52272	HNRNPM	O14757	CHEK1	S452	R456C	456	Missense	distal	4	no	10.492	10.596	EPSD	TCGA;COSMIC	5.604	Up-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	P52272	HNRNPM	O14757	CHEK1	S467	M472I	472	Missense	distal	5	no	6.839	6.808	EPSD	TCGA;COSMIC	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	P52272	HNRNPM	O14757	CHEK1	S467	R471P	471	Missense	distal	4	no	6.839	6.929	EPSD	TCGA;COSMIC	5.604	Up-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	P52272	HNRNPM	O14757	CHEK1	S467	E470D	470	Missense	distal	3	no	6.839	6.937	EPSD	TCGA;COSMIC	5.604	Up-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	P52272	HNRNPM	O14757	CHEK1	S468	M472I	472	Missense	distal	4	no	6.452	6.394	EPSD	TCGA;COSMIC	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	P52272	HNRNPM	O14757	CHEK1	S468	R471P	471	Missense	distal	3	no	6.452	6.784	EPSD	TCGA;COSMIC	5.604	Up-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	P52272	HNRNPM	O14757	CHEK1	S468	E470D	470	Missense	proximal	2	no	6.452	6.370	EPSD	TCGA;COSMIC	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	P52272	HNRNPM	O14757	CHEK1	S481	M486T	486	Missense	distal	5	no	10.530	10.419	EPSD	TCGA	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	P52272	HNRNPM	O14757	CHEK1	S481	V483M	483	Missense	proximal	2	no	10.530	10.709	EPSD	TCGA;ICGC;COSMIC	5.604	Up-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	P52272	HNRNPM	O14757	CHEK1	S481	R485H	485	Missense	distal	4	no	10.530	10.691	EPSD	TCGA;ICGC;COSMIC	5.604	Up-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	P52272	HNRNPM	O14757	CHEK1	S481	R485C	485	Missense	distal	4	no	10.530	10.633	EPSD	TCGA;COSMIC	5.604	Up-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	P52272	HNRNPM	O14757	CHEK1	S528	M529T	529	Missense	proximal	1	no	6.152	6.174	EPSD	TCGA;COSMIC	5.604	Up-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	P52272	HNRNPM	O14757	CHEK1	S528	R524H	524	Missense	distal	-4	no	6.152	5.955	EPSD	TCGA;COSMIC	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	P52272	HNRNPM	O14757	CHEK1	S528	R531C	531	Missense	distal	3	no	6.152	5.205	EPSD	TCGA;ICGC;COSMIC	5.604	Loss
CAMK_CAMKL_CHK1_CHEK1_ST	P52272	HNRNPM	O14757	CHEK1	S528	A535T	535	Missense	distal	7	no	6.152	6.036	EPSD	TCGA;COSMIC	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	P52272	HNRNPM	O14757	CHEK1	S528	S528N	528	Missense	central	0	yes	6.152	0.000	EPSD	TCGA	5.604	Loss
CAMK_CAMKL_CHK1_CHEK1_ST	P52272	HNRNPM	O14757	CHEK1	T553	R557C	557	Missense	distal	4	no	9.689	9.792	EPSD	TCGA;COSMIC	5.604	Up-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	P52272	HNRNPM	O14757	CHEK1	T553	R550H	550	Missense	distal	-3	no	9.689	3.879	EPSD	TCGA;COSMIC	5.604	Loss
CAMK_CAMKL_CHK1_CHEK1_ST	P52272	HNRNPM	O14757	CHEK1	T553	R550C	550	Missense	distal	-3	no	9.689	1.597	EPSD	TCGA;COSMIC;CCLE	5.604	Loss
CAMK_CAMKL_CHK1_CHEK1_ST	P52272	HNRNPM	O14757	CHEK1	T553	A552T	552	Missense	proximal	-1	no	9.689	9.560	EPSD	TCGA;COSMIC	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	P52272	HNRNPM	O14757	CHEK1	S701	E700Q	700	Missense	proximal	-1	no	6.393	6.499	EPSD	TCGA;COSMIC	5.604	Up-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	P52272	HNRNPM	O14757	CHEK1	S701	E706K	706	Missense	distal	5	no	6.393	6.328	EPSD	TCGA;COSMIC	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q15648	MED1	O14757	CHEK1	S18	R22Q	22	Missense	distal	4	no	8.941	8.940	EPSD	TCGA;ICGC;COSMIC	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q15648	MED1	O14757	CHEK1	S18	A25T	25	Missense	distal	7	no	8.941	8.824	EPSD	TCGA;ICGC;COSMIC	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q15648	MED1	O14757	CHEK1	S238	K235R	235	Missense	distal	-3	no	3.498	7.323	EPSD	TCGA;ICGC;COSMIC	5.604	Gain
CAMK_CAMKL_CHK1_CHEK1_ST	Q15648	MED1	O14757	CHEK1	S387	P381A	381	Missense	distal	-6	no	6.340	6.116	EPSD	TCGA;ICGC;COSMIC	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q15648	MED1	O14757	CHEK1	S387	S387R	387	Missense	central	0	yes	6.340	0.000	EPSD	TCGA	5.604	Loss
CAMK_CAMKL_CHK1_CHEK1_ST	Q15648	MED1	O14757	CHEK1	S387	L382F	382	Missense	distal	-5	no	6.340	2.776	EPSD	TCGA;ICGC;COSMIC	5.604	Loss
CAMK_CAMKL_CHK1_CHEK1_ST	Q15648	MED1	O14757	CHEK1	S434	E441K	441	Missense	distal	7	no	6.500	6.335	EPSD	TCGA;ICGC;COSMIC	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q15648	MED1	O14757	CHEK1	S434	S434F	434	Missense	central	0	yes	6.500	0.000	EPSD	TCGA;ICGC;COSMIC	5.604	Loss
CAMK_CAMKL_CHK1_CHEK1_ST	Q15648	MED1	O14757	CHEK1	S434	R427I	427	Missense	distal	-7	no	6.500	6.117	EPSD	TCGA;ICGC;COSMIC	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q15648	MED1	O14757	CHEK1	S434	P435L	435	Missense	proximal	1	no	6.500	6.528	EPSD	TCGA;ICGC;COSMIC	5.604	Up-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q15648	MED1	O14757	CHEK1	S434	G436W	436	Missense	proximal	2	no	6.500	6.296	EPSD	TCGA;ICGC;COSMIC	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q15648	MED1	O14757	CHEK1	S503	M508I	508	Missense	distal	5	no	7.993	7.962	EPSD	TCGA;ICGC;COSMIC	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q15648	MED1	O14757	CHEK1	S588	S588L	588	Missense	central	0	yes	10.283	0.000	EPSD	TCGA;ICGC;COSMIC	5.604	Loss
CAMK_CAMKL_CHK1_CHEK1_ST	Q15648	MED1	O14757	CHEK1	S671	S671Y	671	Missense	central	0	yes	12.462	0.000	EPSD	TCGA;ICGC;COSMIC	5.604	Loss
CAMK_CAMKL_CHK1_CHEK1_ST	Q15648	MED1	O14757	CHEK1	S671	R677H	677	Missense	distal	6	no	12.462	12.750	EPSD	TCGA;ICGC;COSMIC;GDSC;CCLE	5.604	Up-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q15648	MED1	O14757	CHEK1	S671	R677C	677	Missense	distal	6	no	12.462	12.756	EPSD	TCGA	5.604	Up-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q15648	MED1	O14757	CHEK1	S671	S671F	671	Missense	central	0	yes	12.462	0.000	EPSD	TCGA;ICGC;COSMIC	5.604	Loss
CAMK_CAMKL_CHK1_CHEK1_ST	Q15648	MED1	O14757	CHEK1	T704	P700T	700	Missense	distal	-4	no	7.190	6.902	PhosphoSitePlus	TCGA;ICGC;COSMIC	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q15648	MED1	O14757	CHEK1	T704	F708C	708	Missense	distal	4	no	7.190	7.246	PhosphoSitePlus	TCGA;ICGC;COSMIC	5.604	Up-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q15648	MED1	O14757	CHEK1	S771	R768Q	768	Missense	distal	-3	no	7.402	0.195	EPSD	TCGA;ICGC;COSMIC	5.604	Loss
CAMK_CAMKL_CHK1_CHEK1_ST	Q15648	MED1	O14757	CHEK1	S850	G847R	847	Missense	distal	-3	no	-1.718	6.057	EPSD	TCGA;ICGC;COSMIC	5.604	Gain
CAMK_CAMKL_CHK1_CHEK1_ST	Q15648	MED1	O14757	CHEK1	T928	Q925R	925	Missense	distal	-3	no	2.953	10.160	EPSD	TCGA;ICGC	5.604	Gain
CAMK_CAMKL_CHK1_CHEK1_ST	Q15648	MED1	O14757	CHEK1	S1207	P1208A	1208	Missense	proximal	1	no	5.984	6.038	EPSD	TCGA;ICGC;COSMIC	5.604	Up-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q16204	CCDC6	O14757	CHEK1	S17	G14R	14	Missense	distal	-3	no	1.840	9.614	EPSD	TCGA	5.604	Gain
CAMK_CAMKL_CHK1_CHEK1_ST	Q16204	CCDC6	O14757	CHEK1	S65	Q67H	67	Missense	proximal	2	no	12.699	12.189	EPSD	TCGA;ICGC;COSMIC	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q16204	CCDC6	O14757	CHEK1	S240	P243S	243	Missense	distal	3	no	6.503	6.174	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q16204	CCDC6	O14757	CHEK1	S240	R246K	246	Missense	distal	6	no	6.503	6.415	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q16204	CCDC6	O14757	CHEK1	S244	P243S	243	Missense	proximal	-1	no	5.651	5.204	PhosphoSitePlus;EPSD	TCGA;ICGC;COSMIC	5.604	Loss
CAMK_CAMKL_CHK1_CHEK1_ST	Q16204	CCDC6	O14757	CHEK1	S244	R246K	246	Missense	proximal	2	no	5.651	6.337	PhosphoSitePlus;EPSD	TCGA;ICGC;COSMIC	5.604	Up-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q16204	CCDC6	O14757	CHEK1	S249	P243S	243	Missense	distal	-6	no	9.198	9.101	EPSD	TCGA;ICGC;COSMIC	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q16204	CCDC6	O14757	CHEK1	S249	R246K	246	Missense	distal	-3	no	9.198	5.373	EPSD	TCGA;ICGC;COSMIC	5.604	Loss
CAMK_CAMKL_CHK1_CHEK1_ST	Q16204	CCDC6	O14757	CHEK1	S323	R320Q	320	Missense	distal	-3	no	12.375	5.168	EPSD	TCGA;ICGC;COSMIC	5.604	Loss
CAMK_CAMKL_CHK1_CHEK1_ST	Q16204	CCDC6	O14757	CHEK1	S327	R320Q	320	Missense	distal	-7	no	5.399	5.657	EPSD	TCGA;ICGC;COSMIC	5.604	Gain
CAMK_CAMKL_CHK1_CHEK1_ST	Q16204	CCDC6	O14757	CHEK1	T349	R348H	348	Missense	proximal	-1	no	5.569	5.694	EPSD	TCGA;ICGC;COSMIC	5.604	Gain
CAMK_CAMKL_CHK1_CHEK1_ST	Q16204	CCDC6	O14757	CHEK1	S351	R348H	348	Missense	distal	-3	no	5.883	0.074	EPSD	TCGA;ICGC;COSMIC	5.604	Loss
CAMK_CAMKL_CHK1_CHEK1_ST	Q16204	CCDC6	O14757	CHEK1	S351	S351Y	351	Missense	central	0	yes	5.883	0.000	EPSD	TCGA;ICGC;COSMIC	5.604	Loss
CAMK_CAMKL_CHK1_CHEK1_ST	Q16204	CCDC6	O14757	CHEK1	S351	P358H	358	Missense	distal	7	no	5.883	5.627	EPSD	TCGA;ICGC	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q16204	CCDC6	O14757	CHEK1	S367	P365S	365	Missense	proximal	-2	no	9.393	9.109	EPSD	TCGA;ICGC;COSMIC	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q16204	CCDC6	O14757	CHEK1	S417	P412L	412	Missense	distal	-5	no	0.936	5.643	EPSD	TCGA;ICGC;COSMIC	5.604	Gain
CAMK_CAMKL_CHK1_CHEK1_ST	Q16204	CCDC6	O14757	CHEK1	S419	R425W	425	Missense	distal	6	no	6.785	7.252	EPSD	TCGA;ICGC;COSMIC	5.604	Up-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q16204	CCDC6	O14757	CHEK1	S419	F423I	423	Missense	distal	4	no	6.785	6.739	EPSD	TCGA;ICGC;COSMIC	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q16204	CCDC6	O14757	CHEK1	S419	F423L	423	Missense	distal	4	no	6.785	6.724	EPSD	TCGA;COSMIC	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q16204	CCDC6	O14757	CHEK1	S419	P412L	412	Missense	distal	-7	no	6.785	6.571	EPSD	TCGA;ICGC;COSMIC	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q9Y2T7	YBX2	O14757	CHEK1	S189	P188S	188	Missense	proximal	-1	no	12.256	11.809	EPSD	TCGA;ICGC;COSMIC	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q9Y2T7	YBX2	O14757	CHEK1	S189	P188L	188	Missense	proximal	-1	no	12.256	12.070	EPSD	TCGA;ICGC;COSMIC	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q9Y2T7	YBX2	O14757	CHEK1	S189	R182Q	182	Missense	distal	-7	no	12.256	12.514	EPSD	TCGA;ICGC;COSMIC	5.604	Up-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q9Y2T7	YBX2	O14757	CHEK1	S208	G205E	205	Missense	distal	-3	no	5.153	5.839	EPSD	TCGA;ICGC;COSMIC	5.604	Gain
CAMK_CAMKL_CHK1_CHEK1_ST	Q86WB0	ZC3HC1	O14757	CHEK1	T84	R81T	81	Missense	distal	-3	no	10.986	-9.583	PhosphoSitePlus	TCGA;ICGC;COSMIC	5.604	Loss
CAMK_CAMKL_CHK1_CHEK1_ST	Q86WB0	ZC3HC1	O14757	CHEK1	T84	A91T	91	Missense	distal	7	no	10.986	10.869	PhosphoSitePlus	TCGA;ICGC	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q86WB0	ZC3HC1	O14757	CHEK1	T84	A77V	77	Missense	distal	-7	no	10.986	10.329	PhosphoSitePlus	TCGA;ICGC;COSMIC	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q86WB0	ZC3HC1	O14757	CHEK1	S354	V361A	361	Missense	distal	7	no	10.381	10.302	EPSD	TCGA;COSMIC	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q86WB0	ZC3HC1	O14757	CHEK1	S354	R351L	351	Missense	distal	-3	no	10.381	-8.166	EPSD	TCGA;COSMIC	5.604	Loss
CAMK_CAMKL_CHK1_CHEK1_ST	Q86WB0	ZC3HC1	O14757	CHEK1	S354	R351Q	351	Missense	distal	-3	no	10.381	3.174	EPSD	TCGA;COSMIC	5.604	Loss
CAMK_CAMKL_CHK1_CHEK1_ST	Q86WB0	ZC3HC1	O14757	CHEK1	T379	R380Q	380	Missense	proximal	1	no	9.170	9.178	EPSD	TCGA;COSMIC	5.604	Up-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q86WB0	ZC3HC1	O14757	CHEK1	T379	R376C	376	Missense	distal	-3	no	9.170	1.078	EPSD	TCGA;COSMIC	5.604	Loss
CAMK_CAMKL_CHK1_CHEK1_ST	Q86WB0	ZC3HC1	O14757	CHEK1	S407	S410C	410	Missense	distal	3	no	13.059	12.110	EPSD	TCGA;COSMIC	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q86WB0	ZC3HC1	O14757	CHEK1	S407	C406S	406	Missense	proximal	-1	no	13.059	12.863	EPSD	TCGA;COSMIC	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q86WB0	ZC3HC1	O14757	CHEK1	S407	S411L	411	Missense	distal	4	no	13.059	13.096	EPSD	TCGA	5.604	Up-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q86WB0	ZC3HC1	O14757	CHEK1	S471	A467V	467	Missense	distal	-4	no	8.256	8.177	EPSD	TCGA;ICGC;COSMIC	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	P08631	HCK	O14757	CHEK1	S181	S181F	181	Missense	central	0	yes	5.617	0.000	EPSD	TCGA;COSMIC	5.604	Loss
CAMK_CAMKL_CHK1_CHEK1_ST	P08631	HCK	O14757	CHEK1	S296	S298L	298	Missense	proximal	2	no	5.778	5.384	EPSD	TCGA;COSMIC	5.604	Loss
CAMK_CAMKL_CHK1_CHEK1_ST	P08631	HCK	O14757	CHEK1	S296	M292I	292	Missense	distal	-4	no	5.778	5.653	EPSD	TCGA;COSMIC	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	P49790	NUP153	O14757	CHEK1	S297	G302S	302	Missense	distal	5	no	8.363	8.555	PhosphoSitePlus;EPSD	TCGA;ICGC;COSMIC	5.604	Up-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	P49790	NUP153	O14757	CHEK1	S297	M291I	291	Missense	distal	-6	no	8.363	8.300	PhosphoSitePlus;EPSD	TCGA;ICGC;COSMIC	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	P49790	NUP153	O14757	CHEK1	S297	Q295R	295	Missense	proximal	-2	no	8.363	8.317	PhosphoSitePlus;EPSD	TCGA;ICGC	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	P49790	NUP153	O14757	CHEK1	S320	E316Q	316	Missense	distal	-4	no	7.054	7.011	EPSD	TCGA;ICGC;COSMIC	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	P49790	NUP153	O14757	CHEK1	S320	R327K	327	Missense	distal	7	no	7.054	7.129	EPSD	TCGA;ICGC;COSMIC	5.604	Up-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	P49790	NUP153	O14757	CHEK1	S320	R327I	327	Missense	distal	7	no	7.054	6.669	EPSD	TCGA;ICGC;COSMIC	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	P49790	NUP153	O14757	CHEK1	S359	P363S	363	Missense	distal	4	no	6.536	6.396	EPSD	TCGA;ICGC;COSMIC	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	P49790	NUP153	O14757	CHEK1	T369	K371E	371	Missense	proximal	2	no	7.453	7.411	EPSD	TCGA;ICGC	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	P49790	NUP153	O14757	CHEK1	T369	P363S	363	Missense	distal	-6	no	7.453	7.355	EPSD	TCGA;ICGC;COSMIC	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	P49790	NUP153	O14757	CHEK1	S374	K371E	371	Missense	distal	-3	no	6.002	2.739	EPSD	TCGA;ICGC	5.604	Loss
CAMK_CAMKL_CHK1_CHEK1_ST	P49790	NUP153	O14757	CHEK1	S374	S380I	380	Missense	distal	6	no	6.002	6.044	EPSD	TCGA;ICGC;COSMIC	5.604	Up-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	P49790	NUP153	O14757	CHEK1	S374	R379Q	379	Missense	distal	5	no	6.002	6.077	EPSD	TCGA;ICGC;COSMIC	5.604	Up-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	P49790	NUP153	O14757	CHEK1	S607	G606R	606	Missense	proximal	-1	no	7.698	7.681	EPSD	TCGA;ICGC;COSMIC	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	P49790	NUP153	O14757	CHEK1	S607	A600S	600	Missense	distal	-7	no	7.698	7.248	EPSD	TCGA;ICGC;COSMIC	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	P49790	NUP153	O14757	CHEK1	S937	I934R	934	Missense	distal	-3	no	1.062	9.820	EPSD	TCGA;ICGC;COSMIC	5.604	Gain
CAMK_CAMKL_CHK1_CHEK1_ST	P49790	NUP153	O14757	CHEK1	S1019	G1025S	1025	Missense	distal	6	no	9.747	9.535	EPSD	TCGA;ICGC;COSMIC	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	P49790	NUP153	O14757	CHEK1	S1019	E1012D	1012	Missense	distal	-7	no	9.747	9.294	EPSD	TCGA;ICGC	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q9NWH9	SLTM	O14757	CHEK1	S97	D95H	95	Missense	proximal	-2	no	5.727	5.844	EPSD	TCGA;ICGC;COSMIC	5.604	Up-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q9NWH9	SLTM	O14757	CHEK1	S97	A102V	102	Missense	distal	5	no	5.727	5.624	EPSD	TCGA;ICGC;COSMIC	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q9NWH9	SLTM	O14757	CHEK1	S330	K333R	333	Missense	distal	3	no	6.399	5.752	EPSD	TCGA;ICGC;COSMIC	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q9NWH9	SLTM	O14757	CHEK1	S373	G370R	370	Missense	distal	-3	no	-0.306	7.468	EPSD	TCGA;COSMIC	5.604	Gain
CAMK_CAMKL_CHK1_CHEK1_ST	Q9NWH9	SLTM	O14757	CHEK1	T417	R420Q	420	Missense	distal	3	no	5.108	6.170	EPSD	TCGA;ICGC;COSMIC	5.604	Gain
CAMK_CAMKL_CHK1_CHEK1_ST	Q9NWH9	SLTM	O14757	CHEK1	S909	R906I	906	Missense	distal	-3	no	8.091	-0.667	EPSD	TCGA	5.604	Loss
CAMK_CAMKL_CHK1_CHEK1_ST	Q9NWH9	SLTM	O14757	CHEK1	S962	R959Q	959	Missense	distal	-3	no	9.658	2.451	EPSD	TCGA;COSMIC	5.604	Loss
CAMK_CAMKL_CHK1_CHEK1_ST	O15294	OGT	O14757	CHEK1	T819	T819I	819	Missense	central	0	yes	8.146	0.000	EPSD	TCGA;ICGC;COSMIC	5.604	Loss
CAMK_CAMKL_CHK1_CHEK1_ST	O15294	OGT	O14757	CHEK1	T819	T819P	819	Missense	central	0	yes	8.146	0.000	EPSD	TCGA;ICGC;COSMIC	5.604	Loss
CAMK_CAMKL_CHK1_CHEK1_ST	O15294	OGT	O14757	CHEK1	T819	R825H	825	Missense	distal	6	no	8.146	8.434	EPSD	TCGA;ICGC;COSMIC	5.604	Up-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	O15294	OGT	O14757	CHEK1	S1004	Q1011P	1011	Missense	distal	7	no	12.665	12.473	EPSD	TCGA;ICGC	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	O15294	OGT	O14757	CHEK1	S1004	P1005L	1005	Missense	proximal	1	no	12.665	12.693	EPSD	TCGA;ICGC	5.604	Up-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q8NG66	NEK11	O14757	CHEK1	S273	K270T	270	Missense	distal	-3	no	9.778	-6.966	PhosphoSitePlus	TCGA;ICGC;COSMIC	5.604	Loss
CAMK_CAMKL_CHK1_CHEK1_ST	Q8NG66	NEK11	O14757	CHEK1	S273	E280K	280	Missense	distal	7	no	9.778	9.612	PhosphoSitePlus	TCGA;ICGC;COSMIC	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q8NG66	NEK11	O14757	CHEK1	S273	S273L	273	Missense	central	0	yes	9.778	0.000	PhosphoSitePlus	TCGA;ICGC;COSMIC	5.604	Loss
CAMK_CAMKL_CHK1_CHEK1_ST	Q8NG66	NEK11	O14757	CHEK1	S273	P276S	276	Missense	distal	3	no	9.778	9.448	PhosphoSitePlus	TCGA;ICGC;COSMIC;CCLE	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	P10636	MAPT	O14757	CHEK1	T52	P47L	47	Missense	distal	-5	no	1.989	6.696	EPSD	TCGA;ICGC;COSMIC	5.604	Gain
CAMK_CAMKL_CHK1_CHEK1_ST	P10636	MAPT	O14757	CHEK1	S64	P59L	59	Missense	distal	-5	no	0.973	5.680	EPSD	TCGA;ICGC;COSMIC	5.604	Gain
CAMK_CAMKL_CHK1_CHEK1_ST	P10636	MAPT	O14757	CHEK1	S113	E117K	117	Missense	distal	4	no	5.761	5.755	EPSD	TCGA;ICGC;COSMIC	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	P10636	MAPT	O14757	CHEK1	S113	A118V	118	Missense	distal	5	no	5.761	5.658	EPSD	TCGA;ICGC;COSMIC	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	P10636	MAPT	O14757	CHEK1	T167	R168H	168	Missense	proximal	1	no	7.796	7.730	EPSD	TCGA;ICGC;COSMIC	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	P10636	MAPT	O14757	CHEK1	T167	R168C	168	Missense	proximal	1	no	7.796	7.786	EPSD	TCGA;ICGC;COSMIC	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	P10636	MAPT	O14757	CHEK1	S214	P212L	212	Missense	proximal	-2	no	12.525	12.346	EPSD	TCGA;ICGC;COSMIC	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	P10636	MAPT	O14757	CHEK1	S214	E220K	220	Missense	distal	6	no	12.525	12.795	EPSD	TCGA;ICGC;COSMIC	5.604	Up-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	P10636	MAPT	O14757	CHEK1	S341	E348V	348	Missense	distal	7	no	10.855	10.650	EPSD	TCGA;ICGC;COSMIC	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	P10636	MAPT	O14757	CHEK1	S341	G339R	339	Missense	proximal	-2	no	10.855	10.821	EPSD	TCGA;ICGC;COSMIC	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	P10636	MAPT	O14757	CHEK1	S341	S341F	341	Missense	central	0	yes	10.855	0.000	EPSD	TCGA;ICGC;COSMIC	5.604	Loss
CAMK_CAMKL_CHK1_CHEK1_ST	P10636	MAPT	O14757	CHEK1	S369	K366E	366	Missense	distal	-3	no	6.623	3.360	EPSD	TCGA;ICGC;COSMIC	5.604	Loss
CAMK_CAMKL_CHK1_CHEK1_ST	P10636	MAPT	O14757	CHEK1	T386	G387R	387	Missense	proximal	1	no	7.562	7.570	EPSD	TCGA;COSMIC	5.604	Up-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	P10636	MAPT	O14757	CHEK1	S451	E456K	456	Missense	distal	5	no	9.414	9.349	EPSD	TCGA;ICGC;COSMIC	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	P10636	MAPT	O14757	CHEK1	S451	S452C	452	Missense	proximal	1	no	9.414	9.430	EPSD	TCGA;ICGC;COSMIC	5.604	Up-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	P10636	MAPT	O14757	CHEK1	S451	S444F	444	Missense	distal	-7	no	9.414	7.682	EPSD	TCGA;ICGC	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	P10636	MAPT	O14757	CHEK1	S451	S452Y	452	Missense	proximal	1	no	9.414	9.397	EPSD	TCGA;ICGC;COSMIC	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q04837	SSBP1	O14757	CHEK1	S67	G68R	68	Missense	proximal	1	no	8.214	8.223	PhosphoSitePlus	TCGA;COSMIC	5.604	Up-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q04837	SSBP1	O14757	CHEK1	S67	Q74L	74	Missense	distal	7	no	8.214	7.959	PhosphoSitePlus	TCGA;ICGC;COSMIC	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q04837	SSBP1	O14757	CHEK1	S67	V72A	72	Missense	distal	5	no	8.214	8.318	PhosphoSitePlus	TCGA;ICGC;COSMIC	5.604	Up-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q04837	SSBP1	O14757	CHEK1	T130	V125L	125	Missense	distal	-5	no	4.959	8.436	EPSD	TCGA;ICGC;COSMIC	5.604	Gain
CAMK_CAMKL_CHK1_CHEK1_ST	Q14676	MDC1	O14757	CHEK1	S112	D117N	117	Missense	distal	5	no	7.587	7.498	EPSD	TCGA;ICGC;COSMIC	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q14676	MDC1	O14757	CHEK1	S112	L115P	115	Missense	distal	3	no	7.587	8.351	EPSD	TCGA;ICGC;COSMIC	5.604	Up-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q14676	MDC1	O14757	CHEK1	S112	R114H	114	Missense	proximal	2	no	7.587	7.606	EPSD	TCGA;ICGC;COSMIC	5.604	Up-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q14676	MDC1	O14757	CHEK1	S168	L175V	175	Missense	distal	7	no	6.964	7.100	EPSD	TCGA;ICGC;COSMIC	5.604	Up-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q14676	MDC1	O14757	CHEK1	S453	E459K	459	Missense	distal	6	no	6.224	6.494	EPSD	TCGA;ICGC;COSMIC	5.604	Up-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q14676	MDC1	O14757	CHEK1	S485	A479T	479	Missense	distal	-6	no	13.565	13.760	EPSD	TCGA;ICGC;COSMIC	5.604	Up-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q14676	MDC1	O14757	CHEK1	S485	P491S	491	Missense	distal	6	no	13.565	12.945	EPSD	TCGA;ICGC;COSMIC	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q14676	MDC1	O14757	CHEK1	S485	S485P	485	Missense	central	0	yes	13.565	0.000	EPSD	TCGA;ICGC	5.604	Loss
CAMK_CAMKL_CHK1_CHEK1_ST	Q14676	MDC1	O14757	CHEK1	S874	D875H	875	Missense	proximal	1	no	7.950	7.806	EPSD	TCGA;ICGC;COSMIC	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q14676	MDC1	O14757	CHEK1	S874	E879Q	879	Missense	distal	5	no	7.950	7.837	EPSD	TCGA;ICGC;COSMIC	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q14676	MDC1	O14757	CHEK1	S874	S874P	874	Missense	central	0	yes	7.950	0.000	EPSD	TCGA;ICGC	5.604	Loss
CAMK_CAMKL_CHK1_CHEK1_ST	Q14676	MDC1	O14757	CHEK1	S981	S981L	981	Missense	central	0	yes	5.787	0.000	EPSD	TCGA;ICGC;COSMIC	5.604	Loss
CAMK_CAMKL_CHK1_CHEK1_ST	Q14676	MDC1	O14757	CHEK1	S981	V984I	984	Missense	distal	3	no	5.787	5.074	EPSD	TCGA;ICGC	5.604	Loss
CAMK_CAMKL_CHK1_CHEK1_ST	Q14676	MDC1	O14757	CHEK1	S986	S981L	981	Missense	distal	-5	no	2.974	6.162	EPSD	TCGA;ICGC;COSMIC	5.604	Gain
CAMK_CAMKL_CHK1_CHEK1_ST	Q14676	MDC1	O14757	CHEK1	T1220	Q1226E	1226	Missense	distal	6	no	8.632	8.281	EPSD	TCGA;COSMIC	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q14676	MDC1	O14757	CHEK1	T1302	R1308Q	1308	Missense	distal	6	no	8.841	8.834	EPSD	TCGA;COSMIC	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q14676	MDC1	O14757	CHEK1	T1314	R1313K	1313	Missense	proximal	-1	no	8.538	8.390	EPSD	TCGA;COSMIC	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q14676	MDC1	O14757	CHEK1	T1314	R1308Q	1308	Missense	distal	-6	no	8.538	8.620	EPSD	TCGA;COSMIC	5.604	Up-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q14676	MDC1	O14757	CHEK1	T1314	T1321I	1321	Missense	distal	7	no	8.538	8.313	EPSD	TCGA;COSMIC	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q14676	MDC1	O14757	CHEK1	T1478	R1480K	1480	Missense	proximal	2	no	4.978	5.664	EPSD	TCGA;COSMIC	5.604	Gain
CAMK_CAMKL_CHK1_CHEK1_ST	Q14676	MDC1	O14757	CHEK1	T1688	S1686Y	1686	Missense	proximal	-2	no	7.838	7.951	EPSD	TCGA;COSMIC	5.604	Up-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q14676	MDC1	O14757	CHEK1	T1781	L1778R	1778	Missense	distal	-3	no	-10.217	8.330	EPSD	TCGA;ICGC;COSMIC	5.604	Gain
CAMK_CAMKL_CHK1_CHEK1_ST	Q14676	MDC1	O14757	CHEK1	S1814	K1812N	1812	Missense	proximal	-2	no	8.693	8.963	EPSD	TCGA;ICGC;COSMIC	5.604	Up-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q14676	MDC1	O14757	CHEK1	S1814	S1820L	1820	Missense	distal	6	no	8.693	9.102	EPSD	TCGA;ICGC;COSMIC	5.604	Up-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q14676	MDC1	O14757	CHEK1	S1814	R1811H	1811	Missense	distal	-3	no	8.693	2.883	EPSD	TCGA;ICGC;COSMIC	5.604	Loss
CAMK_CAMKL_CHK1_CHEK1_ST	Q14676	MDC1	O14757	CHEK1	S1878	R1879H	1879	Missense	proximal	1	no	7.677	7.611	EPSD	TCGA;ICGC	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q14676	MDC1	O14757	CHEK1	S1878	I1876M	1876	Missense	proximal	-2	no	7.677	7.691	EPSD	TCGA;ICGC	5.604	Up-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q14676	MDC1	O14757	CHEK1	S1878	T1884S	1884	Missense	distal	6	no	7.677	7.366	EPSD	TCGA;ICGC;COSMIC	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	P52292	KPNA2	O14757	CHEK1	T25	R29C	29	Missense	distal	4	no	6.135	6.238	EPSD	TCGA;ICGC;COSMIC	5.604	Up-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	P52292	KPNA2	O14757	CHEK1	T25	M27T	27	Missense	proximal	2	no	6.135	5.670	EPSD	TCGA;ICGC;COSMIC	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	P52292	KPNA2	O14757	CHEK1	T25	D23N	23	Missense	proximal	-2	no	6.135	6.277	EPSD	TCGA;ICGC;COSMIC	5.604	Up-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	P52292	KPNA2	O14757	CHEK1	T25	D23H	23	Missense	proximal	-2	no	6.135	6.251	EPSD	TCGA;ICGC;COSMIC	5.604	Up-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	P52292	KPNA2	O14757	CHEK1	S54	T61A	61	Missense	distal	7	no	11.941	12.057	PhosphoSitePlus	TCGA;ICGC;COSMIC	5.604	Up-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	P52292	KPNA2	O14757	CHEK1	S54	D59N	59	Missense	distal	5	no	11.941	11.852	PhosphoSitePlus	TCGA;ICGC;COSMIC	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	P52292	KPNA2	O14757	CHEK1	S54	P57S	57	Missense	distal	3	no	11.941	11.612	PhosphoSitePlus	TCGA;ICGC;COSMIC	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	P52292	KPNA2	O14757	CHEK1	S54	R51I	51	Missense	distal	-3	no	11.941	3.183	PhosphoSitePlus	TCGA;ICGC;COSMIC	5.604	Loss
CAMK_CAMKL_CHK1_CHEK1_ST	P52292	KPNA2	O14757	CHEK1	T230	S234C	234	Missense	distal	4	no	5.966	6.121	EPSD	TCGA;ICGC;COSMIC	5.604	Up-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	P52292	KPNA2	O14757	CHEK1	T230	L233H	233	Missense	distal	3	no	5.966	6.428	EPSD	TCGA;ICGC;COSMIC	5.604	Up-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	P52292	KPNA2	O14757	CHEK1	T230	R227C	227	Missense	distal	-3	no	5.966	-2.125	EPSD	TCGA;ICGC;COSMIC	5.604	Loss
CAMK_CAMKL_CHK1_CHEK1_ST	O95707	POP4	O14757	CHEK1	S10	A8V	8	Missense	proximal	-2	no	6.269	6.346	PhosphoSitePlus	TCGA;ICGC;COSMIC	5.604	Up-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	O95707	POP4	O14757	CHEK1	S10	A14V	14	Missense	distal	4	no	6.269	6.187	PhosphoSitePlus	TCGA;COSMIC	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	O95707	POP4	O14757	CHEK1	S17	D18Y	18	Missense	proximal	1	no	6.378	6.256	EPSD	TCGA;ICGC;COSMIC	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	O95707	POP4	O14757	CHEK1	S17	D18N	18	Missense	proximal	1	no	6.378	6.271	EPSD	TCGA;ICGC;COSMIC	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	O95707	POP4	O14757	CHEK1	S17	A14V	14	Missense	distal	-3	no	6.378	4.626	EPSD	TCGA;COSMIC	5.604	Loss
CAMK_CAMKL_CHK1_CHEK1_ST	P35612	ADD2	O14757	CHEK1	S62	E65K	65	Missense	distal	3	no	6.159	5.343	EPSD	TCGA;ICGC;COSMIC	5.604	Loss
CAMK_CAMKL_CHK1_CHEK1_ST	P35612	ADD2	O14757	CHEK1	S62	M56I	56	Missense	distal	-6	no	6.159	6.096	EPSD	TCGA;ICGC;COSMIC	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	P35612	ADD2	O14757	CHEK1	S396	A402V	402	Missense	distal	6	no	10.020	9.908	EPSD	TCGA;ICGC;COSMIC	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	P35612	ADD2	O14757	CHEK1	S396	S396R	396	Missense	central	0	yes	10.020	0.000	EPSD	TCGA;ICGC;COSMIC	5.604	Loss
CAMK_CAMKL_CHK1_CHEK1_ST	P35612	ADD2	O14757	CHEK1	S396	T392P	392	Missense	distal	-4	no	10.020	10.307	EPSD	TCGA;ICGC;COSMIC	5.604	Up-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	P35612	ADD2	O14757	CHEK1	S532	S530N	530	Missense	proximal	-2	no	10.836	11.025	EPSD	TCGA;ICGC;COSMIC	5.604	Up-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	P35612	ADD2	O14757	CHEK1	S667	E660K	660	Missense	distal	-7	no	6.906	7.604	EPSD	TCGA;ICGC;COSMIC	5.604	Up-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	P35612	ADD2	O14757	CHEK1	T671	T675M	675	Missense	distal	4	no	6.141	6.240	EPSD	TCGA;COSMIC	5.604	Up-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	P35612	ADD2	O14757	CHEK1	S686	T679A	679	Missense	distal	-7	no	4.705	6.021	EPSD	TCGA;ICGC;COSMIC	5.604	Gain
CAMK_CAMKL_CHK1_CHEK1_ST	P35612	ADD2	O14757	CHEK1	T711	K707N	707	Missense	distal	-4	no	6.300	6.186	EPSD	TCGA;ICGC;COSMIC	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	P35612	ADD2	O14757	CHEK1	T711	P712L	712	Missense	proximal	1	no	6.300	6.328	EPSD	TCGA;ICGC;COSMIC	5.604	Up-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	P35612	ADD2	O14757	CHEK1	S713	K707N	707	Missense	distal	-6	no	8.097	8.229	PhosphoSitePlus	TCGA;ICGC;COSMIC	5.604	Up-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	P35612	ADD2	O14757	CHEK1	S713	P712L	712	Missense	proximal	-1	no	8.097	7.911	PhosphoSitePlus	TCGA;ICGC;COSMIC	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	P35611	ADD1	O14757	CHEK1	S59	P65H	65	Missense	distal	6	no	5.981	5.737	EPSD	TCGA;ICGC;COSMIC	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	P35611	ADD1	O14757	CHEK1	S353	R354C	354	Missense	proximal	1	no	6.163	6.154	EPSD	TCGA;ICGC;COSMIC	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	P35611	ADD1	O14757	CHEK1	S355	R354C	354	Missense	proximal	-1	no	7.969	8.004	EPSD	TCGA;ICGC;COSMIC	5.604	Up-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	P35611	ADD1	O14757	CHEK1	T470	S468L	468	Missense	proximal	-2	no	5.527	5.632	EPSD	TCGA;ICGC;COSMIC;CCLE	5.604	Gain
CAMK_CAMKL_CHK1_CHEK1_ST	Q6UB98	ANKRD12	O14757	CHEK1	S526	S524Y	524	Missense	proximal	-2	no	7.615	7.727	EPSD	TCGA;ICGC;COSMIC	5.604	Up-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q6UB98	ANKRD12	O14757	CHEK1	T632	E627K	627	Missense	distal	-5	no	3.412	5.974	EPSD	TCGA;ICGC;COSMIC	5.604	Gain
CAMK_CAMKL_CHK1_CHEK1_ST	Q6UB98	ANKRD12	O14757	CHEK1	S1047	K1046I	1046	Missense	proximal	-1	no	10.093	10.198	EPSD	TCGA;COSMIC	5.604	Up-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q6UB98	ANKRD12	O14757	CHEK1	S1047	K1044N	1044	Missense	distal	-3	no	10.093	3.551	EPSD	TCGA;ICGC;COSMIC	5.604	Loss
CAMK_CAMKL_CHK1_CHEK1_ST	Q6UB98	ANKRD12	O14757	CHEK1	S1047	S1047F	1047	Missense	central	0	yes	10.093	0.000	EPSD	TCGA;ICGC;COSMIC	5.604	Loss
CAMK_CAMKL_CHK1_CHEK1_ST	Q6UB98	ANKRD12	O14757	CHEK1	S1056	S1056L	1056	Missense	central	0	yes	6.113	0.000	EPSD	TCGA;ICGC;COSMIC	5.604	Loss
CAMK_CAMKL_CHK1_CHEK1_ST	Q6UB98	ANKRD12	O14757	CHEK1	S1311	S1311R	1311	Missense	central	0	yes	6.033	0.000	EPSD	TCGA;ICGC;COSMIC	5.604	Loss
CAMK_CAMKL_CHK1_CHEK1_ST	Q6UB98	ANKRD12	O14757	CHEK1	S1311	M1312I	1312	Missense	proximal	1	no	6.033	6.011	EPSD	TCGA;ICGC;COSMIC	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q6UB98	ANKRD12	O14757	CHEK1	S1650	M1655I	1655	Missense	distal	5	no	7.093	7.062	EPSD	TCGA;ICGC;COSMIC	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q6UB98	ANKRD12	O14757	CHEK1	S1650	L1645W	1645	Missense	distal	-5	no	7.093	3.257	EPSD	TCGA;ICGC;COSMIC	5.604	Loss
CAMK_CAMKL_CHK1_CHEK1_ST	Q6UB98	ANKRD12	O14757	CHEK1	S1758	T1755R	1755	Missense	distal	-3	no	-10.706	9.863	EPSD	TCGA;ICGC;COSMIC	5.604	Gain
CAMK_CAMKL_CHK1_CHEK1_ST	Q6UB98	ANKRD12	O14757	CHEK1	S1790	R1791C	1791	Missense	proximal	1	no	9.650	9.640	EPSD	TCGA;ICGC;COSMIC	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q9H8N7	ZNF395	O14757	CHEK1	S66	L70P	70	Missense	distal	4	no	6.704	6.808	EPSD	TCGA;ICGC;COSMIC	5.604	Up-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q9H8N7	ZNF395	O14757	CHEK1	S66	K63E	63	Missense	distal	-3	no	6.704	3.441	EPSD	TCGA;ICGC;COSMIC	5.604	Loss
CAMK_CAMKL_CHK1_CHEK1_ST	Q9H8N7	ZNF395	O14757	CHEK1	S66	S68L	68	Missense	proximal	2	no	6.704	6.310	EPSD	TCGA;ICGC	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q9H8N7	ZNF395	O14757	CHEK1	T67	L70P	70	Missense	distal	3	no	5.172	5.936	EPSD	TCGA;ICGC;COSMIC	5.604	Gain
CAMK_CAMKL_CHK1_CHEK1_ST	Q9H8N7	ZNF395	O14757	CHEK1	S275	P269A	269	Missense	distal	-6	no	8.740	8.517	EPSD	TCGA;ICGC;COSMIC	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q9H8N7	ZNF395	O14757	CHEK1	S275	S275F	275	Missense	central	0	yes	8.740	0.000	EPSD	TCGA;ICGC;COSMIC	5.604	Loss
CAMK_CAMKL_CHK1_CHEK1_ST	Q9H8N7	ZNF395	O14757	CHEK1	S275	K273N	273	Missense	proximal	-2	no	8.740	9.011	EPSD	TCGA;ICGC	5.604	Up-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q9H8N7	ZNF395	O14757	CHEK1	S376	S377T	377	Missense	proximal	1	no	7.777	7.785	EPSD	TCGA;ICGC;COSMIC	5.604	Up-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q9H8N7	ZNF395	O14757	CHEK1	S376	P382S	382	Missense	distal	6	no	7.777	7.158	EPSD	TCGA;ICGC;COSMIC	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q9H8N7	ZNF395	O14757	CHEK1	S447	S441C	441	Missense	distal	-6	no	8.186	8.222	PhosphoSitePlus	TCGA;ICGC;COSMIC	5.604	Up-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q9H8N7	ZNF395	O14757	CHEK1	S447	S451G	451	Missense	distal	4	no	8.186	8.253	PhosphoSitePlus	TCGA;ICGC;COSMIC	5.604	Up-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q9H8N7	ZNF395	O14757	CHEK1	S447	V443F	443	Missense	distal	-4	no	8.186	7.644	PhosphoSitePlus	TCGA;ICGC;COSMIC	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q9H8N7	ZNF395	O14757	CHEK1	S447	E452K	452	Missense	distal	5	no	8.186	8.121	PhosphoSitePlus	TCGA;ICGC;COSMIC	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q9H8N7	ZNF395	O14757	CHEK1	S447	P453H	453	Missense	distal	6	no	8.186	7.942	PhosphoSitePlus	TCGA;ICGC;COSMIC	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q9H8N7	ZNF395	O14757	CHEK1	S449	S451G	451	Missense	proximal	2	no	10.362	10.297	EPSD	TCGA;ICGC;COSMIC	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q9H8N7	ZNF395	O14757	CHEK1	S449	V443F	443	Missense	distal	-6	no	10.362	10.624	EPSD	TCGA;ICGC;COSMIC	5.604	Up-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q9H8N7	ZNF395	O14757	CHEK1	S449	E452K	452	Missense	distal	3	no	10.362	9.546	EPSD	TCGA;ICGC;COSMIC	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q9H8N7	ZNF395	O14757	CHEK1	S449	P453H	453	Missense	distal	4	no	10.362	10.434	EPSD	TCGA;ICGC;COSMIC	5.604	Up-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q9H8N7	ZNF395	O14757	CHEK1	S474	R480L	480	Missense	distal	6	no	8.825	9.147	EPSD	TCGA;ICGC;COSMIC	5.604	Up-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q9H8N7	ZNF395	O14757	CHEK1	S474	G481W	481	Missense	distal	7	no	8.825	8.318	EPSD	TCGA;ICGC;COSMIC	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q9H8N7	ZNF395	O14757	CHEK1	S474	P469L	469	Missense	distal	-5	no	8.825	13.532	EPSD	TCGA;ICGC;COSMIC	5.604	Up-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q9H8N7	ZNF395	O14757	CHEK1	S474	G481R	481	Missense	distal	7	no	8.825	8.819	EPSD	TCGA;ICGC;COSMIC	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	P12956	XRCC6	O14757	CHEK1	S53	M48I	48	Missense	distal	-5	no	5.603	7.945	EPSD	TCGA;ICGC;COSMIC	5.604	Gain
CAMK_CAMKL_CHK1_CHEK1_ST	P12956	XRCC6	O14757	CHEK1	T170	K164N	164	Missense	distal	-6	no	8.495	8.627	EPSD	TCGA;ICGC;COSMIC	5.604	Up-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	P12956	XRCC6	O14757	CHEK1	T334	K331N	331	Missense	distal	-3	no	6.400	-0.143	EPSD	TCGA;ICGC;COSMIC;GDSC;CCLE	5.604	Loss
CAMK_CAMKL_CHK1_CHEK1_ST	P12956	XRCC6	O14757	CHEK1	S477	R470H	470	Missense	distal	-7	no	12.198	12.139	PhosphoSitePlus	TCGA;ICGC;COSMIC	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	P12956	XRCC6	O14757	CHEK1	S477	E479Q	479	Missense	proximal	2	no	12.198	12.083	PhosphoSitePlus	TCGA;ICGC;COSMIC	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	P12956	XRCC6	O14757	CHEK1	S477	V482M	482	Missense	distal	5	no	12.198	12.171	PhosphoSitePlus	TCGA;ICGC;COSMIC	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	P12956	XRCC6	O14757	CHEK1	S520	A513V	513	Missense	distal	-7	no	11.067	10.411	EPSD	TCGA;ICGC;COSMIC	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	P12956	XRCC6	O14757	CHEK1	S520	A513T	513	Missense	distal	-7	no	11.067	9.751	EPSD	TCGA;GDSC	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q13257	MAD2L1	O14757	CHEK1	S6	L3R	3	Missense	distal	-3	no	-9.247	9.300	EPSD	TCGA;ICGC;COSMIC	5.604	Gain
CAMK_CAMKL_CHK1_CHEK1_ST	Q13257	MAD2L1	O14757	CHEK1	S185	R182L	182	Missense	distal	-3	no	7.770	-10.777	PhosphoSitePlus;EPSD	TCGA;ICGC;COSMIC	5.604	Loss
CAMK_CAMKL_CHK1_CHEK1_ST	Q13257	MAD2L1	O14757	CHEK1	S185	H191R	191	Missense	distal	6	no	7.770	7.482	PhosphoSitePlus;EPSD	TCGA;ICGC;COSMIC	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q13257	MAD2L1	O14757	CHEK1	S185	R184C	184	Missense	proximal	-1	no	7.770	7.805	PhosphoSitePlus;EPSD	TCGA;ICGC;COSMIC	5.604	Up-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q13257	MAD2L1	O14757	CHEK1	T187	R182L	182	Missense	distal	-5	no	6.561	9.538	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	5.604	Up-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q13257	MAD2L1	O14757	CHEK1	T187	H191R	191	Missense	distal	4	no	6.561	6.400	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q13257	MAD2L1	O14757	CHEK1	T187	R184C	184	Missense	distal	-3	no	6.561	-1.530	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	5.604	Loss
CAMK_CAMKL_CHK1_CHEK1_ST	Q13043	STK4	O14757	CHEK1	T120	R117Q	117	Missense	distal	-3	no	8.540	1.333	EPSD	TCGA;ICGC;COSMIC;GDSC;CCLE	5.604	Loss
CAMK_CAMKL_CHK1_CHEK1_ST	Q13043	STK4	O14757	CHEK1	T120	T120M	120	Missense	central	0	yes	8.540	0.000	EPSD	TCGA;ICGC;COSMIC	5.604	Loss
CAMK_CAMKL_CHK1_CHEK1_ST	Q13043	STK4	O14757	CHEK1	T120	R115Q	115	Missense	distal	-5	no	8.540	8.144	EPSD	TCGA;ICGC;COSMIC	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q13043	STK4	O14757	CHEK1	T122	T128A	128	Missense	distal	6	no	6.461	6.538	EPSD	TCGA;ICGC;COSMIC	5.604	Up-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q13043	STK4	O14757	CHEK1	T122	R117Q	117	Missense	distal	-5	no	6.461	6.064	EPSD	TCGA;ICGC;COSMIC;GDSC;CCLE	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q13043	STK4	O14757	CHEK1	T122	T120M	120	Missense	proximal	-2	no	6.461	6.349	EPSD	TCGA;ICGC;COSMIC	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q13043	STK4	O14757	CHEK1	T122	R115Q	115	Missense	distal	-7	no	6.461	6.719	EPSD	TCGA;ICGC;COSMIC	5.604	Up-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q13043	STK4	O14757	CHEK1	T243	P240R	240	Missense	distal	-3	no	1.302	8.439	EPSD	TCGA;COSMIC	5.604	Gain
CAMK_CAMKL_CHK1_CHEK1_ST	Q13043	STK4	O14757	CHEK1	S307	D313Y	313	Missense	distal	6	no	12.367	13.292	EPSD	TCGA	5.604	Up-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q13043	STK4	O14757	CHEK1	S307	Q305H	305	Missense	proximal	-2	no	12.367	12.385	EPSD	TCGA;COSMIC	5.604	Up-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q13043	STK4	O14757	CHEK1	T387	E386K	386	Missense	proximal	-1	no	8.578	8.521	EPSD	TCGA;COSMIC	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	O75592	MYCBP2	O14757	CHEK1	S87	K82E	82	Missense	distal	-5	no	9.871	7.310	EPSD	TCGA	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	O75592	MYCBP2	O14757	CHEK1	S87	N94K	94	Missense	distal	7	no	9.871	9.810	EPSD	TCGA;COSMIC	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	O75592	MYCBP2	O14757	CHEK1	S87	R86I	86	Missense	proximal	-1	no	9.871	9.828	EPSD	TCGA	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	O75592	MYCBP2	O14757	CHEK1	S89	K82E	82	Missense	distal	-7	no	9.675	8.977	EPSD	TCGA	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	O75592	MYCBP2	O14757	CHEK1	S89	N94K	94	Missense	distal	5	no	9.675	9.697	EPSD	TCGA;COSMIC	5.604	Up-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	O75592	MYCBP2	O14757	CHEK1	S89	R86I	86	Missense	distal	-3	no	9.675	0.917	EPSD	TCGA	5.604	Loss
CAMK_CAMKL_CHK1_CHEK1_ST	O75592	MYCBP2	O14757	CHEK1	S351	G352R	352	Missense	proximal	1	no	9.354	9.363	EPSD	TCGA;COSMIC	5.604	Up-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	O75592	MYCBP2	O14757	CHEK1	S351	K348N	348	Missense	distal	-3	no	9.354	2.811	EPSD	TCGA	5.604	Loss
CAMK_CAMKL_CHK1_CHEK1_ST	O75592	MYCBP2	O14757	CHEK1	S861	P863S	863	Missense	proximal	2	no	12.192	12.269	EPSD	TCGA;COSMIC	5.604	Up-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	O75592	MYCBP2	O14757	CHEK1	S1176	A1183V	1183	Missense	distal	7	no	6.584	6.663	EPSD	TCGA;COSMIC	5.604	Up-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	O75592	MYCBP2	O14757	CHEK1	S1176	D1169N	1169	Missense	distal	-7	no	6.584	6.276	EPSD	TCGA;COSMIC	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	O75592	MYCBP2	O14757	CHEK1	S1176	Q1182R	1182	Missense	distal	6	no	6.584	6.590	EPSD	TCGA;COSMIC	5.604	Up-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	O75592	MYCBP2	O14757	CHEK1	S1176	V1174A	1174	Missense	proximal	-2	no	6.584	6.507	EPSD	TCGA	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	O75592	MYCBP2	O14757	CHEK1	S1189	A1183V	1183	Missense	distal	-6	no	7.319	7.457	EPSD	TCGA;COSMIC	5.604	Up-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	O75592	MYCBP2	O14757	CHEK1	S1189	K1186Q	1186	Missense	distal	-3	no	7.319	3.937	EPSD	TCGA;COSMIC	5.604	Loss
CAMK_CAMKL_CHK1_CHEK1_ST	O75592	MYCBP2	O14757	CHEK1	S1189	Q1182R	1182	Missense	distal	-7	no	7.319	7.061	EPSD	TCGA;COSMIC	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	O75592	MYCBP2	O14757	CHEK1	S1472	E1473Q	1473	Missense	proximal	1	no	7.680	7.614	EPSD	TCGA;COSMIC	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	O75592	MYCBP2	O14757	CHEK1	S1586	E1588D	1588	Missense	proximal	2	no	6.682	6.600	EPSD	TCGA	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	O75592	MYCBP2	O14757	CHEK1	S1586	E1588K	1588	Missense	proximal	2	no	6.682	6.724	EPSD	TCGA	5.604	Up-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	O75592	MYCBP2	O14757	CHEK1	S1586	R1579Q	1579	Missense	distal	-7	no	6.682	6.940	EPSD	TCGA;COSMIC	5.604	Up-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	O75592	MYCBP2	O14757	CHEK1	S1757	G1763E	1763	Missense	distal	6	no	7.310	6.828	EPSD	TCGA;COSMIC	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	O75592	MYCBP2	O14757	CHEK1	S2281	K2279N	2279	Missense	proximal	-2	no	8.573	8.844	EPSD	TCGA;COSMIC	5.604	Up-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	O75592	MYCBP2	O14757	CHEK1	S2281	Q2277E	2277	Missense	distal	-4	no	8.573	8.616	EPSD	TCGA;COSMIC	5.604	Up-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	O75592	MYCBP2	O14757	CHEK1	S2281	S2276T	2276	Missense	distal	-5	no	8.573	9.705	EPSD	TCGA;COSMIC	5.604	Up-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	O75592	MYCBP2	O14757	CHEK1	S2281	S2276Y	2276	Missense	distal	-5	no	8.573	7.889	EPSD	TCGA	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	O75592	MYCBP2	O14757	CHEK1	S2353	P2354Q	2354	Missense	proximal	1	no	6.610	6.681	EPSD	TCGA;COSMIC	5.604	Up-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	O75592	MYCBP2	O14757	CHEK1	S2353	R2350H	2350	Missense	distal	-3	no	6.610	0.801	EPSD	TCGA;COSMIC	5.604	Loss
CAMK_CAMKL_CHK1_CHEK1_ST	O75592	MYCBP2	O14757	CHEK1	S2353	R2350C	2350	Missense	distal	-3	no	6.610	-1.481	EPSD	TCGA;COSMIC;GDSC	5.604	Loss
CAMK_CAMKL_CHK1_CHEK1_ST	O75592	MYCBP2	O14757	CHEK1	T2355	P2354Q	2354	Missense	proximal	-1	no	6.273	6.003	EPSD	TCGA;COSMIC	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	O75592	MYCBP2	O14757	CHEK1	T2355	R2350H	2350	Missense	distal	-5	no	6.273	3.808	EPSD	TCGA;COSMIC	5.604	Loss
CAMK_CAMKL_CHK1_CHEK1_ST	O75592	MYCBP2	O14757	CHEK1	T2355	R2350C	2350	Missense	distal	-5	no	6.273	5.595	EPSD	TCGA;COSMIC;GDSC	5.604	Loss
CAMK_CAMKL_CHK1_CHEK1_ST	O75592	MYCBP2	O14757	CHEK1	S2445	A2439V	2439	Missense	distal	-6	no	8.657	8.795	EPSD	TCGA;ICGC;COSMIC;CCLE	5.604	Up-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	O75592	MYCBP2	O14757	CHEK1	S2445	R2442H	2442	Missense	distal	-3	no	8.657	2.848	EPSD	TCGA;ICGC	5.604	Loss
CAMK_CAMKL_CHK1_CHEK1_ST	O75592	MYCBP2	O14757	CHEK1	S2643	D2640H	2640	Missense	distal	-3	no	3.763	7.290	EPSD	TCGA;COSMIC	5.604	Gain
CAMK_CAMKL_CHK1_CHEK1_ST	O75592	MYCBP2	O14757	CHEK1	S2652	S2649R	2649	Missense	distal	-3	no	-0.908	8.788	EPSD	TCGA;COSMIC	5.604	Gain
CAMK_CAMKL_CHK1_CHEK1_ST	O75592	MYCBP2	O14757	CHEK1	S2661	D2668H	2668	Missense	distal	7	no	7.309	6.718	EPSD	TCGA;COSMIC	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	O75592	MYCBP2	O14757	CHEK1	S2684	I2681M	2681	Missense	distal	-3	no	4.389	7.998	EPSD	TCGA;COSMIC	5.604	Gain
CAMK_CAMKL_CHK1_CHEK1_ST	O75592	MYCBP2	O14757	CHEK1	S2689	S2685F	2685	Missense	distal	-4	no	5.830	5.588	EPSD	TCGA;COSMIC	5.604	Loss
CAMK_CAMKL_CHK1_CHEK1_ST	O75592	MYCBP2	O14757	CHEK1	S2689	S2684F	2684	Missense	distal	-5	no	5.830	5.455	EPSD	TCGA	5.604	Loss
CAMK_CAMKL_CHK1_CHEK1_ST	O75592	MYCBP2	O14757	CHEK1	S2745	K2740M	2740	Missense	distal	-5	no	9.153	6.581	EPSD	TCGA;COSMIC	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	O75592	MYCBP2	O14757	CHEK1	S2745	S2751Y	2751	Missense	distal	6	no	9.153	9.895	EPSD	TCGA	5.604	Up-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	O75592	MYCBP2	O14757	CHEK1	S2768	M2766I	2766	Missense	proximal	-2	no	10.948	10.934	EPSD	TCGA;COSMIC	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	O75592	MYCBP2	O14757	CHEK1	S2768	P2775A	2775	Missense	distal	7	no	10.948	10.942	EPSD	TCGA;COSMIC	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	O75592	MYCBP2	O14757	CHEK1	S2768	K2761T	2761	Missense	distal	-7	no	10.948	9.161	EPSD	TCGA;COSMIC	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	O75592	MYCBP2	O14757	CHEK1	S2774	P2775A	2775	Missense	proximal	1	no	6.470	6.525	EPSD	TCGA;COSMIC	5.604	Up-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	O75592	MYCBP2	O14757	CHEK1	S2794	S2801Y	2801	Missense	distal	7	no	6.415	5.900	EPSD	TCGA	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	O75592	MYCBP2	O14757	CHEK1	S2806	L2812V	2812	Missense	distal	6	no	10.069	9.935	EPSD	TCGA;COSMIC	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	O75592	MYCBP2	O14757	CHEK1	S2806	R2803C	2803	Missense	distal	-3	no	10.069	1.977	EPSD	TCGA;COSMIC	5.604	Loss
CAMK_CAMKL_CHK1_CHEK1_ST	O75592	MYCBP2	O14757	CHEK1	S2806	N2811S	2811	Missense	distal	5	no	10.069	10.070	EPSD	TCGA;COSMIC	5.604	Up-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	O75592	MYCBP2	O14757	CHEK1	S2806	P2807S	2807	Missense	proximal	1	no	10.069	10.105	EPSD	TCGA;COSMIC	5.604	Up-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	O75592	MYCBP2	O14757	CHEK1	S2806	S2801Y	2801	Missense	distal	-5	no	10.069	9.384	EPSD	TCGA	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	O75592	MYCBP2	O14757	CHEK1	S2831	P2827S	2827	Missense	distal	-4	no	7.183	6.946	EPSD	TCGA;COSMIC	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	O75592	MYCBP2	O14757	CHEK1	S2831	R2830C	2830	Missense	proximal	-1	no	7.183	7.218	EPSD	TCGA;COSMIC;CCLE	5.604	Up-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	O75592	MYCBP2	O14757	CHEK1	S2833	P2840L	2840	Missense	distal	7	no	5.981	5.918	EPSD	TCGA;COSMIC	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	O75592	MYCBP2	O14757	CHEK1	S2833	P2827S	2827	Missense	distal	-6	no	5.981	5.883	EPSD	TCGA;COSMIC	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	O75592	MYCBP2	O14757	CHEK1	S2833	R2830C	2830	Missense	distal	-3	no	5.981	-2.111	EPSD	TCGA;COSMIC;CCLE	5.604	Loss
CAMK_CAMKL_CHK1_CHEK1_ST	O75592	MYCBP2	O14757	CHEK1	S2858	L2854F	2854	Missense	distal	-4	no	6.461	6.167	EPSD	TCGA;COSMIC	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	O75592	MYCBP2	O14757	CHEK1	S2858	R2857W	2857	Missense	proximal	-1	no	6.461	6.578	EPSD	TCGA	5.604	Up-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	O75592	MYCBP2	O14757	CHEK1	S2860	L2854F	2854	Missense	distal	-6	no	10.860	11.109	EPSD	TCGA;COSMIC	5.604	Up-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	O75592	MYCBP2	O14757	CHEK1	S2860	R2857W	2857	Missense	distal	-3	no	10.860	-22.743	EPSD	TCGA	5.604	Loss
CAMK_CAMKL_CHK1_CHEK1_ST	O75592	MYCBP2	O14757	CHEK1	S2865	S2870Y	2870	Missense	distal	5	no	5.740	5.286	EPSD	TCGA	5.604	Loss
CAMK_CAMKL_CHK1_CHEK1_ST	O75592	MYCBP2	O14757	CHEK1	S2882	S2876F	2876	Missense	distal	-6	no	6.114	6.387	EPSD	TCGA;COSMIC	5.604	Up-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	O75592	MYCBP2	O14757	CHEK1	S2882	S2882C	2882	Missense	central	0	yes	6.114	0.000	EPSD	TCGA;COSMIC	5.604	Loss
CAMK_CAMKL_CHK1_CHEK1_ST	O75592	MYCBP2	O14757	CHEK1	S2907	N2906Y	2906	Missense	proximal	-1	no	7.040	7.151	EPSD	TCGA;COSMIC	5.604	Up-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	O75592	MYCBP2	O14757	CHEK1	S2907	D2910Y	2910	Missense	distal	3	no	7.040	4.255	EPSD	TCGA;COSMIC	5.604	Loss
CAMK_CAMKL_CHK1_CHEK1_ST	O75592	MYCBP2	O14757	CHEK1	S3084	K3081N	3081	Missense	distal	-3	no	6.362	-0.181	EPSD	TCGA;ICGC;COSMIC	5.604	Loss
CAMK_CAMKL_CHK1_CHEK1_ST	O75592	MYCBP2	O14757	CHEK1	S3084	P3090L	3090	Missense	distal	6	no	6.362	6.152	EPSD	TCGA;ICGC;COSMIC	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	O75592	MYCBP2	O14757	CHEK1	S3339	Q3336K	3336	Missense	distal	-3	no	3.797	7.178	EPSD	TCGA;ICGC	5.604	Gain
CAMK_CAMKL_CHK1_CHEK1_ST	O75592	MYCBP2	O14757	CHEK1	S3388	M3381T	3381	Missense	distal	-7	no	6.107	5.641	EPSD	TCGA;ICGC	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	O75592	MYCBP2	O14757	CHEK1	S3440	S3440L	3440	Missense	central	0	yes	12.195	0.000	EPSD	TCGA;COSMIC	5.604	Loss
CAMK_CAMKL_CHK1_CHEK1_ST	O75592	MYCBP2	O14757	CHEK1	S3440	R3437I	3437	Missense	distal	-3	no	12.195	3.437	EPSD	TCGA;COSMIC	5.604	Loss
CAMK_CAMKL_CHK1_CHEK1_ST	O75592	MYCBP2	O14757	CHEK1	S3467	G3468A	3468	Missense	proximal	1	no	9.344	9.345	EPSD	TCGA;COSMIC	5.604	Up-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	O75592	MYCBP2	O14757	CHEK1	S3467	V3472A	3472	Missense	distal	5	no	9.344	9.448	EPSD	TCGA;COSMIC	5.604	Up-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	O75592	MYCBP2	O14757	CHEK1	S3481	L3477F	3477	Missense	distal	-4	no	12.798	12.504	EPSD	TCGA;COSMIC	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	O75592	MYCBP2	O14757	CHEK1	S3481	R3486W	3486	Missense	distal	5	no	12.798	12.630	EPSD	TCGA;COSMIC	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	O75592	MYCBP2	O14757	CHEK1	S3481	P3480L	3480	Missense	proximal	-1	no	12.798	12.612	EPSD	TCGA;COSMIC	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	O75592	MYCBP2	O14757	CHEK1	S3489	R3486W	3486	Missense	distal	-3	no	10.182	-23.422	EPSD	TCGA;COSMIC	5.604	Loss
CAMK_CAMKL_CHK1_CHEK1_ST	O75592	MYCBP2	O14757	CHEK1	S3758	R3765Q	3765	Missense	distal	7	no	10.523	10.677	EPSD	TCGA	5.604	Up-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	O75592	MYCBP2	O14757	CHEK1	S3758	N3753S	3753	Missense	distal	-5	no	10.523	10.030	EPSD	TCGA;COSMIC	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	O75592	MYCBP2	O14757	CHEK1	T4088	T4093A	4093	Missense	distal	5	no	5.527	5.768	EPSD	TCGA;COSMIC	5.604	Gain
CAMK_CAMKL_CHK1_CHEK1_ST	O75592	MYCBP2	O14757	CHEK1	T4088	K4084E	4084	Missense	distal	-4	no	5.527	5.629	EPSD	TCGA;COSMIC	5.604	Gain
CAMK_CAMKL_CHK1_CHEK1_ST	O75592	MYCBP2	O14757	CHEK1	T4089	T4093A	4093	Missense	distal	4	no	7.236	7.418	EPSD	TCGA;COSMIC	5.604	Up-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	O75592	MYCBP2	O14757	CHEK1	T4089	K4084E	4084	Missense	distal	-5	no	7.236	4.674	EPSD	TCGA;COSMIC	5.604	Loss
CAMK_CAMKL_CHK1_CHEK1_ST	Q9BRD0	BUD13	O14757	CHEK1	T135	H133L	133	Missense	proximal	-2	no	9.017	8.958	EPSD	TCGA;ICGC;COSMIC	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q9BRD0	BUD13	O14757	CHEK1	T135	P140T	140	Missense	distal	5	no	9.017	8.876	EPSD	TCGA;ICGC;COSMIC	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q9BRD0	BUD13	O14757	CHEK1	T135	S139F	139	Missense	distal	4	no	9.017	9.115	EPSD	TCGA;ICGC;COSMIC	5.604	Up-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q9BRD0	BUD13	O14757	CHEK1	T135	K142N	142	Missense	distal	7	no	9.017	9.078	EPSD	TCGA;ICGC	5.604	Up-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q9BRD0	BUD13	O14757	CHEK1	T135	P136L	136	Missense	proximal	1	no	9.017	9.044	EPSD	TCGA;ICGC;COSMIC	5.604	Up-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q9BRD0	BUD13	O14757	CHEK1	T147	S151C	151	Missense	distal	4	no	10.525	10.679	EPSD	TCGA;ICGC;COSMIC	5.604	Up-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q9BRD0	BUD13	O14757	CHEK1	T147	P140T	140	Missense	distal	-7	no	10.525	10.328	EPSD	TCGA;ICGC;COSMIC	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q9BRD0	BUD13	O14757	CHEK1	T147	D149Y	149	Missense	proximal	2	no	10.525	9.762	EPSD	TCGA;ICGC;COSMIC	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q9BRD0	BUD13	O14757	CHEK1	T147	K142N	142	Missense	distal	-5	no	10.525	9.631	EPSD	TCGA;ICGC	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q9BRD0	BUD13	O14757	CHEK1	T159	R156P	156	Missense	distal	-3	no	8.933	1.797	EPSD	TCGA;ICGC;COSMIC	5.604	Loss
CAMK_CAMKL_CHK1_CHEK1_ST	Q9BRD0	BUD13	O14757	CHEK1	S172	H170R	170	Missense	proximal	-2	no	7.652	7.587	EPSD	TCGA;ICGC;COSMIC	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q9BRD0	BUD13	O14757	CHEK1	S172	R178S	178	Missense	distal	6	no	7.652	7.564	EPSD	TCGA;ICGC;COSMIC	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q9BRD0	BUD13	O14757	CHEK1	S172	R178K	178	Missense	distal	6	no	7.652	7.564	EPSD	TCGA;ICGC;COSMIC	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q9BRD0	BUD13	O14757	CHEK1	S184	R178S	178	Missense	distal	-6	no	11.487	11.568	EPSD	TCGA;ICGC;COSMIC	5.604	Up-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q9BRD0	BUD13	O14757	CHEK1	S184	R178K	178	Missense	distal	-6	no	11.487	11.477	EPSD	TCGA;ICGC;COSMIC	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q9BRD0	BUD13	O14757	CHEK1	S184	P189L	189	Missense	distal	5	no	11.487	11.326	EPSD	TCGA;ICGC;COSMIC	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q9BRD0	BUD13	O14757	CHEK1	S185	R178S	178	Missense	distal	-7	no	5.452	5.712	EPSD	TCGA;ICGC;COSMIC	5.604	Gain
CAMK_CAMKL_CHK1_CHEK1_ST	Q9BRD0	BUD13	O14757	CHEK1	S185	R178K	178	Missense	distal	-7	no	5.452	6.632	EPSD	TCGA;ICGC;COSMIC	5.604	Gain
CAMK_CAMKL_CHK1_CHEK1_ST	Q9BRD0	BUD13	O14757	CHEK1	S197	P200S	200	Missense	distal	3	no	11.188	10.858	EPSD	TCGA;ICGC;COSMIC	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q9BRD0	BUD13	O14757	CHEK1	S197	S197F	197	Missense	central	0	yes	11.188	0.000	EPSD	TCGA;ICGC;COSMIC	5.604	Loss
CAMK_CAMKL_CHK1_CHEK1_ST	Q9BRD0	BUD13	O14757	CHEK1	S197	R204S	204	Missense	distal	7	no	11.188	11.095	EPSD	TCGA;ICGC;COSMIC	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q9BRD0	BUD13	O14757	CHEK1	S222	H220R	220	Missense	proximal	-2	no	11.661	11.596	EPSD	TCGA;ICGC;COSMIC	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q9BRD0	BUD13	O14757	CHEK1	S222	H220Y	220	Missense	proximal	-2	no	11.661	11.610	EPSD	TCGA;ICGC;COSMIC	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q9BRD0	BUD13	O14757	CHEK1	S235	S236L	236	Missense	proximal	1	no	9.590	9.581	EPSD	TCGA;ICGC;COSMIC	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q9BRD0	BUD13	O14757	CHEK1	S235	S239C	239	Missense	distal	4	no	9.590	9.744	EPSD	TCGA;ICGC;COSMIC	5.604	Up-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q9BRD0	BUD13	O14757	CHEK1	S235	R230Q	230	Missense	distal	-5	no	9.590	9.194	EPSD	TCGA;ICGC;COSMIC	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q9BRD0	BUD13	O14757	CHEK1	S271	S271F	271	Missense	central	0	yes	7.796	0.000	EPSD	TCGA;ICGC;COSMIC	5.604	Loss
CAMK_CAMKL_CHK1_CHEK1_ST	Q9BRD0	BUD13	O14757	CHEK1	S271	D273Y	273	Missense	proximal	2	no	7.796	7.033	EPSD	TCGA;ICGC;COSMIC	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q9BRD0	BUD13	O14757	CHEK1	S271	D270V	270	Missense	proximal	-1	no	7.796	7.922	EPSD	TCGA;ICGC	5.604	Up-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q9BRD0	BUD13	O14757	CHEK1	S296	K297N	297	Missense	proximal	1	no	9.392	9.363	EPSD	TCGA;COSMIC	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q9BRD0	BUD13	O14757	CHEK1	S296	R293I	293	Missense	distal	-3	no	9.392	0.634	EPSD	TCGA;ICGC;COSMIC	5.604	Loss
CAMK_CAMKL_CHK1_CHEK1_ST	Q9BRD0	BUD13	O14757	CHEK1	S364	P359L	359	Missense	distal	-5	no	1.148	5.855	EPSD	TCGA;COSMIC	5.604	Gain
CAMK_CAMKL_CHK1_CHEK1_ST	Q9BRD0	BUD13	O14757	CHEK1	S385	H383Q	383	Missense	proximal	-2	no	8.920	8.902	EPSD	TCGA;COSMIC	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q9BRD0	BUD13	O14757	CHEK1	S385	R384W	384	Missense	proximal	-1	no	8.920	9.038	EPSD	TCGA;COSMIC	5.604	Up-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	O60343	TBC1D4	O14757	CHEK1	S66	E61K	61	Missense	distal	-5	no	9.780	12.342	EPSD	TCGA;ICGC;COSMIC	5.604	Up-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	O60343	TBC1D4	O14757	CHEK1	S318	R315W	315	Missense	distal	-3	no	9.143	-24.460	EPSD	TCGA;COSMIC	5.604	Loss
CAMK_CAMKL_CHK1_CHEK1_ST	O60343	TBC1D4	O14757	CHEK1	S318	R315Q	315	Missense	distal	-3	no	9.143	1.936	EPSD	TCGA;ICGC;COSMIC	5.604	Loss
CAMK_CAMKL_CHK1_CHEK1_ST	O60343	TBC1D4	O14757	CHEK1	S341	A342T	342	Missense	proximal	1	no	7.708	7.697	EPSD	TCGA;ICGC;COSMIC	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	O60343	TBC1D4	O14757	CHEK1	S341	R336Q	336	Missense	distal	-5	no	7.708	7.312	EPSD	TCGA;ICGC;COSMIC;CCLE	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	O60343	TBC1D4	O14757	CHEK1	S485	L487V	487	Missense	proximal	2	no	10.062	10.349	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	5.604	Up-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	O60343	TBC1D4	O14757	CHEK1	S588	R594W	594	Missense	distal	6	no	11.594	12.061	PhosphoSitePlus;EPSD	TCGA;ICGC;COSMIC	5.604	Up-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	O60343	TBC1D4	O14757	CHEK1	S588	R585W	585	Missense	distal	-3	no	11.594	-22.009	PhosphoSitePlus;EPSD	TCGA;ICGC	5.604	Loss
CAMK_CAMKL_CHK1_CHEK1_ST	O60343	TBC1D4	O14757	CHEK1	S597	R594W	594	Missense	distal	-3	no	9.239	-24.364	EPSD	TCGA;ICGC;COSMIC	5.604	Loss
CAMK_CAMKL_CHK1_CHEK1_ST	O60343	TBC1D4	O14757	CHEK1	S605	S609F	609	Missense	distal	4	no	7.953	8.051	EPSD	TCGA;ICGC;COSMIC	5.604	Up-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	O60343	TBC1D4	O14757	CHEK1	S673	C677R	677	Missense	distal	4	no	11.329	11.225	EPSD	TCGA;ICGC	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	O60343	TBC1D4	O14757	CHEK1	T749	K747E	747	Missense	proximal	-2	no	7.985	8.128	EPSD	TCGA;COSMIC	5.604	Up-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	O60343	TBC1D4	O14757	CHEK1	T749	G743E	743	Missense	distal	-6	no	7.985	7.825	EPSD	TCGA	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	O60343	TBC1D4	O14757	CHEK1	T749	R748S	748	Missense	proximal	-1	no	7.985	7.824	EPSD	TCGA;COSMIC	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	O60343	TBC1D4	O14757	CHEK1	T749	R748M	748	Missense	proximal	-1	no	7.985	8.035	EPSD	TCGA;COSMIC	5.604	Up-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	O60343	TBC1D4	O14757	CHEK1	S750	K747E	747	Missense	distal	-3	no	6.571	3.308	EPSD	TCGA;COSMIC	5.604	Loss
CAMK_CAMKL_CHK1_CHEK1_ST	O60343	TBC1D4	O14757	CHEK1	S750	G743E	743	Missense	distal	-7	no	6.571	7.016	EPSD	TCGA	5.604	Up-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	O60343	TBC1D4	O14757	CHEK1	S750	R748S	748	Missense	proximal	-2	no	6.571	6.472	EPSD	TCGA;COSMIC	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	O60343	TBC1D4	O14757	CHEK1	S750	R748M	748	Missense	proximal	-2	no	6.571	6.614	EPSD	TCGA;COSMIC	5.604	Up-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	O60343	TBC1D4	O14757	CHEK1	S751	K747E	747	Missense	distal	-4	no	10.184	10.287	EPSD	TCGA;COSMIC	5.604	Up-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	O60343	TBC1D4	O14757	CHEK1	S751	R748S	748	Missense	distal	-3	no	10.184	0.488	EPSD	TCGA;COSMIC	5.604	Loss
CAMK_CAMKL_CHK1_CHEK1_ST	O60343	TBC1D4	O14757	CHEK1	S751	R748M	748	Missense	distal	-3	no	10.184	5.036	EPSD	TCGA;COSMIC	5.604	Loss
CAMK_CAMKL_CHK1_CHEK1_ST	O60343	TBC1D4	O14757	CHEK1	S771	R773W	773	Missense	proximal	2	no	9.775	9.600	EPSD	TCGA;COSMIC	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	O60343	TBC1D4	O14757	CHEK1	S771	V765A	765	Missense	distal	-6	no	9.775	9.637	EPSD	TCGA;COSMIC	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	O60343	TBC1D4	O14757	CHEK1	S782	P788S	788	Missense	distal	6	no	8.379	7.760	EPSD	TCGA;COSMIC	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	O60343	TBC1D4	O14757	CHEK1	S822	E824K	824	Missense	proximal	2	no	9.075	9.116	EPSD	TCGA;COSMIC	5.604	Up-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	O60343	TBC1D4	O14757	CHEK1	S822	G823E	823	Missense	proximal	1	no	9.075	9.158	EPSD	TCGA;COSMIC	5.604	Up-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	O60343	TBC1D4	O14757	CHEK1	S822	P816L	816	Missense	distal	-6	no	9.075	9.002	EPSD	TCGA;COSMIC	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	O60343	TBC1D4	O14757	CHEK1	S822	D825V	825	Missense	distal	3	no	9.075	7.856	EPSD	TCGA;COSMIC	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	O60343	TBC1D4	O14757	CHEK1	S822	K829N	829	Missense	distal	7	no	9.075	9.136	EPSD	TCGA;COSMIC	5.604	Up-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	O60343	TBC1D4	O14757	CHEK1	S951	Q946H	946	Missense	distal	-5	no	6.741	4.672	EPSD	TCGA;COSMIC	5.604	Loss
CAMK_CAMKL_CHK1_CHEK1_ST	O60343	TBC1D4	O14757	CHEK1	S1207	E1203D	1203	Missense	distal	-4	no	11.305	11.164	EPSD	TCGA;COSMIC	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	O60343	TBC1D4	O14757	CHEK1	S1207	K1201E	1201	Missense	distal	-6	no	11.305	11.273	EPSD	TCGA;COSMIC	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	P36507	MAP2K2	O14757	CHEK1	T59	L58V	58	Missense	proximal	-1	no	7.692	7.686	PhosphoSitePlus	TCGA;ICGC;COSMIC	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	P36507	MAP2K2	O14757	CHEK1	T59	E66K	66	Missense	distal	7	no	7.692	7.526	PhosphoSitePlus	TCGA;ICGC;COSMIC	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	P36507	MAP2K2	O14757	CHEK1	T59	F57L	57	Missense	proximal	-2	no	7.692	7.507	PhosphoSitePlus	TCGA;ICGC;COSMIC	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	P36507	MAP2K2	O14757	CHEK1	T59	R53W	53	Missense	distal	-6	no	7.692	8.012	PhosphoSitePlus	TCGA;ICGC	5.604	Up-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	P36507	MAP2K2	O14757	CHEK1	T59	F57V	57	Missense	proximal	-2	no	7.692	7.593	PhosphoSitePlus	TCGA;ICGC;COSMIC	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	P36507	MAP2K2	O14757	CHEK1	T59	R53Q	53	Missense	distal	-6	no	7.692	7.774	PhosphoSitePlus	TCGA;ICGC;COSMIC	5.604	Up-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	P36507	MAP2K2	O14757	CHEK1	T59	G65S	65	Missense	distal	6	no	7.692	7.480	PhosphoSitePlus	TCGA;ICGC;COSMIC	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	P36507	MAP2K2	O14757	CHEK1	T59	K63R	63	Missense	distal	4	no	7.692	7.790	PhosphoSitePlus	TCGA;ICGC;COSMIC	5.604	Up-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	P36507	MAP2K2	O14757	CHEK1	S295	H292R	292	Missense	distal	-3	no	4.391	10.200	EPSD	TCGA;ICGC;COSMIC	5.604	Gain
CAMK_CAMKL_CHK1_CHEK1_ST	P36507	MAP2K2	O14757	CHEK1	S306	R313W	313	Missense	distal	7	no	8.439	7.938	EPSD	TCGA;ICGC;COSMIC;CCLE	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q9GZR7	DDX24	O14757	CHEK1	S82	E86Q	86	Missense	distal	4	no	7.723	7.814	PhosphoSitePlus	TCGA	5.604	Up-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q9GZR7	DDX24	O14757	CHEK1	S82	E85Q	85	Missense	distal	3	no	7.723	7.322	PhosphoSitePlus	TCGA;ICGC;COSMIC	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q9GZR7	DDX24	O14757	CHEK1	S82	A80S	80	Missense	proximal	-2	no	7.723	7.608	PhosphoSitePlus	TCGA;ICGC;COSMIC	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q9GZR7	DDX24	O14757	CHEK1	S208	F212Y	212	Missense	distal	4	no	8.739	8.815	EPSD	TCGA;ICGC;COSMIC	5.604	Up-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q9GZR7	DDX24	O14757	CHEK1	S208	L204F	204	Missense	distal	-4	no	8.739	8.445	EPSD	TCGA;ICGC;COSMIC	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q14247	CTTN	O14757	CHEK1	S113	G120V	120	Missense	distal	7	no	11.869	11.899	EPSD	TCGA;ICGC;COSMIC	5.604	Up-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q14247	CTTN	O14757	CHEK1	S113	Q114P	114	Missense	proximal	1	no	11.869	11.798	EPSD	TCGA;ICGC;COSMIC	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q14247	CTTN	O14757	CHEK1	S113	S113L	113	Missense	central	0	yes	11.869	0.000	EPSD	TCGA;ICGC;COSMIC;GDSC;CCLE	5.604	Loss
CAMK_CAMKL_CHK1_CHEK1_ST	Q14247	CTTN	O14757	CHEK1	S150	E146G	146	Missense	distal	-4	no	10.762	10.585	EPSD	TCGA;ICGC;COSMIC	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q14247	CTTN	O14757	CHEK1	S150	S155F	155	Missense	distal	5	no	10.762	10.437	EPSD	TCGA;ICGC;COSMIC	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q14247	CTTN	O14757	CHEK1	S150	G143R	143	Missense	distal	-7	no	10.762	10.724	EPSD	TCGA;ICGC;COSMIC	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q14247	CTTN	O14757	CHEK1	S155	Y162C	162	Missense	distal	7	no	6.590	6.792	EPSD	TCGA;ICGC;COSMIC	5.604	Up-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q14247	CTTN	O14757	CHEK1	S155	S155F	155	Missense	central	0	yes	6.590	0.000	EPSD	TCGA;ICGC;COSMIC	5.604	Loss
CAMK_CAMKL_CHK1_CHEK1_ST	Q14247	CTTN	O14757	CHEK1	S187	R189K	189	Missense	proximal	2	no	9.171	9.857	EPSD	TCGA;ICGC;COSMIC	5.604	Up-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q14247	CTTN	O14757	CHEK1	S187	S192F	192	Missense	distal	5	no	9.171	8.846	EPSD	TCGA;ICGC;COSMIC	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q14247	CTTN	O14757	CHEK1	S187	H185L	185	Missense	proximal	-2	no	9.171	9.113	EPSD	TCGA;ICGC;COSMIC	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q14247	CTTN	O14757	CHEK1	S192	R189K	189	Missense	distal	-3	no	9.783	5.957	EPSD	TCGA;ICGC;COSMIC	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q14247	CTTN	O14757	CHEK1	S192	S192F	192	Missense	central	0	yes	9.783	0.000	EPSD	TCGA;ICGC;COSMIC	5.604	Loss
CAMK_CAMKL_CHK1_CHEK1_ST	Q14247	CTTN	O14757	CHEK1	S192	H185L	185	Missense	distal	-7	no	9.783	9.217	EPSD	TCGA;ICGC;COSMIC	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q14247	CTTN	O14757	CHEK1	S224	H222R	222	Missense	proximal	-2	no	8.271	8.207	EPSD	TCGA;ICGC;COSMIC	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q14247	CTTN	O14757	CHEK1	S224	T219M	219	Missense	distal	-5	no	8.271	5.954	EPSD	TCGA;ICGC;COSMIC	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q14247	CTTN	O14757	CHEK1	S282	A284V	284	Missense	proximal	2	no	8.959	8.396	EPSD	TCGA;COSMIC;CCLE	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q9BTD8	RBM42	O14757	CHEK1	S406	R399H	399	Missense	distal	-7	no	11.286	11.226	PhosphoSitePlus	TCGA;COSMIC	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q9BTD8	RBM42	O14757	CHEK1	S406	P405S	405	Missense	proximal	-1	no	11.286	10.839	PhosphoSitePlus	TCGA;COSMIC	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q9BTD8	RBM42	O14757	CHEK1	S406	A400T	400	Missense	distal	-6	no	11.286	11.481	PhosphoSitePlus	TCGA;COSMIC	5.604	Up-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	P39748	FEN1	O14757	CHEK1	T195	R192Q	192	Missense	distal	-3	no	12.080	4.873	PhosphoSitePlus	TCGA;ICGC;COSMIC	5.604	Loss
CAMK_CAMKL_CHK1_CHEK1_ST	P39748	FEN1	O14757	CHEK1	S255	K254N	254	Missense	proximal	-1	no	8.229	8.435	EPSD	TCGA;ICGC;COSMIC	5.604	Up-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	P39748	FEN1	O14757	CHEK1	S255	S255I	255	Missense	central	0	yes	8.229	0.000	EPSD	TCGA;ICGC;COSMIC	5.604	Loss
CAMK_CAMKL_CHK1_CHEK1_ST	P39748	FEN1	O14757	CHEK1	S255	V260M	260	Missense	distal	5	no	8.229	8.202	EPSD	TCGA;ICGC;COSMIC	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	P39748	FEN1	O14757	CHEK1	S335	R339H	339	Missense	distal	4	no	8.627	8.788	EPSD	TCGA;ICGC;COSMIC;GDSC;CCLE	5.604	Up-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	P39748	FEN1	O14757	CHEK1	S335	Q333H	333	Missense	proximal	-2	no	8.627	8.645	EPSD	TCGA;ICGC;COSMIC	5.604	Up-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q99848	EBNA1BP2	O14757	CHEK1	S207	K204T	204	Missense	distal	-3	no	6.142	-10.601	EPSD	TCGA;ICGC	5.604	Loss
CAMK_CAMKL_CHK1_CHEK1_ST	Q99848	EBNA1BP2	O14757	CHEK1	S207	K204E	204	Missense	distal	-3	no	6.142	2.879	EPSD	TCGA;ICGC	5.604	Loss
CAMK_CAMKL_CHK1_CHEK1_ST	Q13263	TRIM28	O14757	CHEK1	S138	F134L	134	Missense	distal	-4	no	5.776	6.070	EPSD	TCGA;ICGC;COSMIC	5.604	Up-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q13263	TRIM28	O14757	CHEK1	S138	S138G	138	Missense	central	0	yes	5.776	0.000	EPSD	TCGA;ICGC;COSMIC	5.604	Loss
CAMK_CAMKL_CHK1_CHEK1_ST	Q13263	TRIM28	O14757	CHEK1	S138	E131D	131	Missense	distal	-7	no	5.776	5.323	EPSD	TCGA;ICGC;COSMIC;CCLE	5.604	Loss
CAMK_CAMKL_CHK1_CHEK1_ST	Q13263	TRIM28	O14757	CHEK1	S285	S279N	279	Missense	distal	-6	no	8.908	8.949	EPSD	TCGA;COSMIC	5.604	Up-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q13263	TRIM28	O14757	CHEK1	S285	V287I	287	Missense	proximal	2	no	8.908	8.509	EPSD	TCGA;ICGC;COSMIC	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q13263	TRIM28	O14757	CHEK1	S285	Q288R	288	Missense	distal	3	no	8.908	7.846	EPSD	TCGA;ICGC;COSMIC	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q13263	TRIM28	O14757	CHEK1	T415	P422S	422	Missense	distal	7	no	5.657	5.602	EPSD	TCGA;ICGC;COSMIC	5.604	Loss
CAMK_CAMKL_CHK1_CHEK1_ST	Q13263	TRIM28	O14757	CHEK1	T415	E411D	411	Missense	distal	-4	no	5.657	5.516	EPSD	TCGA;ICGC	5.604	Loss
CAMK_CAMKL_CHK1_CHEK1_ST	Q13263	TRIM28	O14757	CHEK1	T415	R412H	412	Missense	distal	-3	no	5.657	-0.152	EPSD	TCGA;ICGC	5.604	Loss
CAMK_CAMKL_CHK1_CHEK1_ST	Q13263	TRIM28	O14757	CHEK1	S437	S437C	437	Missense	central	0	yes	9.298	0.000	EPSD	TCGA;ICGC;COSMIC	5.604	Loss
CAMK_CAMKL_CHK1_CHEK1_ST	Q13263	TRIM28	O14757	CHEK1	S437	S439R	439	Missense	proximal	2	no	9.298	9.203	EPSD	TCGA;COSMIC	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q13263	TRIM28	O14757	CHEK1	S437	M443I	443	Missense	distal	6	no	9.298	8.940	EPSD	TCGA;ICGC;COSMIC	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q13263	TRIM28	O14757	CHEK1	S473	G480S	480	Missense	distal	7	no	8.214	8.116	PhosphoSitePlus	TCGA;ICGC	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q13263	TRIM28	O14757	CHEK1	S473	R472H	472	Missense	proximal	-1	no	8.214	8.340	PhosphoSitePlus	TCGA;COSMIC	5.604	Up-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q13263	TRIM28	O14757	CHEK1	S594	P590S	590	Missense	distal	-4	no	8.218	7.981	EPSD	TCGA;ICGC;COSMIC	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q13263	TRIM28	O14757	CHEK1	S594	A587V	587	Missense	distal	-7	no	8.218	7.561	EPSD	TCGA;ICGC;COSMIC	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q13263	TRIM28	O14757	CHEK1	S594	S598G	598	Missense	distal	4	no	8.218	8.285	EPSD	TCGA	5.604	Up-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q13263	TRIM28	O14757	CHEK1	S594	R591H	591	Missense	distal	-3	no	8.218	2.408	EPSD	TCGA;ICGC	5.604	Loss
CAMK_CAMKL_CHK1_CHEK1_ST	Q13263	TRIM28	O14757	CHEK1	S752	Y755C	755	Missense	distal	3	no	6.033	6.311	EPSD	TCGA;ICGC;COSMIC	5.604	Up-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q13263	TRIM28	O14757	CHEK1	S756	Y755C	755	Missense	proximal	-1	no	8.323	8.190	EPSD	TCGA;ICGC;COSMIC	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	P49792	RANBP2	O14757	CHEK1	S26	M27I	27	Missense	proximal	1	no	10.697	10.675	EPSD	TCGA;ICGC;COSMIC	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	P49792	RANBP2	O14757	CHEK1	S26	G29A	29	Missense	distal	3	no	10.697	10.878	EPSD	TCGA;ICGC;COSMIC	5.604	Up-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	P49792	RANBP2	O14757	CHEK1	S767	R769Q	769	Missense	proximal	2	no	6.870	7.399	EPSD	TCGA;ICGC;COSMIC	5.604	Up-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	P49792	RANBP2	O14757	CHEK1	T1226	I1221T	1221	Missense	distal	-5	no	10.522	10.498	EPSD	TCGA;ICGC;COSMIC	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	P49792	RANBP2	O14757	CHEK1	T1226	R1231C	1231	Missense	distal	5	no	10.522	10.278	EPSD	TCGA;ICGC;COSMIC	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	P49792	RANBP2	O14757	CHEK1	T1310	N1311D	1311	Missense	proximal	1	no	6.861	6.968	EPSD	TCGA;ICGC	5.604	Up-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	P49792	RANBP2	O14757	CHEK1	T1310	K1306Q	1306	Missense	distal	-4	no	6.861	6.920	EPSD	TCGA;ICGC	5.604	Up-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	P49792	RANBP2	O14757	CHEK1	T1525	P1518S	1518	Missense	distal	-7	no	5.080	5.750	EPSD	TCGA;ICGC;COSMIC	5.604	Gain
CAMK_CAMKL_CHK1_CHEK1_ST	P49792	RANBP2	O14757	CHEK1	S1773	F1775Y	1775	Missense	proximal	2	no	5.636	5.484	EPSD	TCGA	5.604	Loss
CAMK_CAMKL_CHK1_CHEK1_ST	P49792	RANBP2	O14757	CHEK1	S1773	I1780V	1780	Missense	distal	7	no	5.636	6.057	EPSD	TCGA;ICGC;COSMIC	5.604	Up-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	P49792	RANBP2	O14757	CHEK1	S1773	K1769N	1769	Missense	distal	-4	no	5.636	5.522	EPSD	TCGA;ICGC;COSMIC	5.604	Loss
CAMK_CAMKL_CHK1_CHEK1_ST	P49792	RANBP2	O14757	CHEK1	S1773	A1770V	1770	Missense	distal	-3	no	5.636	3.885	EPSD	TCGA;ICGC	5.604	Loss
CAMK_CAMKL_CHK1_CHEK1_ST	P49792	RANBP2	O14757	CHEK1	S1833	S1832F	1832	Missense	proximal	-1	no	6.053	6.327	EPSD	TCGA;ICGC;COSMIC	5.604	Up-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	P49792	RANBP2	O14757	CHEK1	S1833	G1834A	1834	Missense	proximal	1	no	6.053	6.054	EPSD	TCGA;ICGC;COSMIC	5.604	Up-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	P49792	RANBP2	O14757	CHEK1	S1955	T1954I	1954	Missense	proximal	-1	no	9.165	9.078	EPSD	TCGA	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	P49792	RANBP2	O14757	CHEK1	S1972	F1968L	1968	Missense	distal	-4	no	6.041	6.335	EPSD	TCGA;ICGC;COSMIC	5.604	Up-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	P49792	RANBP2	O14757	CHEK1	S1972	G1975V	1975	Missense	distal	3	no	6.041	6.467	EPSD	TCGA;ICGC;COSMIC	5.604	Up-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	P49792	RANBP2	O14757	CHEK1	S1972	D1965Y	1965	Missense	distal	-7	no	6.041	4.613	EPSD	TCGA;ICGC;COSMIC	5.604	Loss
CAMK_CAMKL_CHK1_CHEK1_ST	P49792	RANBP2	O14757	CHEK1	S1972	F1971L	1971	Missense	proximal	-1	no	6.041	6.027	EPSD	TCGA;ICGC;COSMIC	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	P49792	RANBP2	O14757	CHEK1	S1972	N1967H	1967	Missense	distal	-5	no	6.041	3.294	EPSD	TCGA;ICGC;COSMIC	5.604	Loss
CAMK_CAMKL_CHK1_CHEK1_ST	P49792	RANBP2	O14757	CHEK1	S1972	F1979L	1979	Missense	distal	7	no	6.041	6.463	EPSD	TCGA;ICGC	5.604	Up-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	P49792	RANBP2	O14757	CHEK1	T1992	G1994R	1994	Missense	proximal	2	no	5.696	5.666	EPSD	TCGA;ICGC;COSMIC	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	P49792	RANBP2	O14757	CHEK1	T2289	Q2286H	2286	Missense	distal	-3	no	4.419	5.817	EPSD	TCGA;ICGC;COSMIC	5.604	Gain
CAMK_CAMKL_CHK1_CHEK1_ST	P49792	RANBP2	O14757	CHEK1	T2458	H2452Y	2452	Missense	distal	-6	no	6.832	6.964	EPSD	TCGA;ICGC;COSMIC	5.604	Up-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	P49792	RANBP2	O14757	CHEK1	S2839	E2834K	2834	Missense	distal	-5	no	4.346	6.908	EPSD	TCGA;ICGC;COSMIC	5.604	Gain
CAMK_CAMKL_CHK1_CHEK1_ST	Q9BQG0	MYBBP1A	O14757	CHEK1	T79	L77V	77	Missense	proximal	-2	no	8.017	8.103	EPSD	TCGA;ICGC;COSMIC	5.604	Up-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q9BQG0	MYBBP1A	O14757	CHEK1	T79	R76C	76	Missense	distal	-3	no	8.017	-0.075	EPSD	TCGA;ICGC	5.604	Loss
CAMK_CAMKL_CHK1_CHEK1_ST	Q9BQG0	MYBBP1A	O14757	CHEK1	S399	V395M	395	Missense	distal	-4	no	7.515	7.359	EPSD	TCGA;ICGC;COSMIC	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q9BQG0	MYBBP1A	O14757	CHEK1	T637	I640M	640	Missense	distal	3	no	6.856	7.143	EPSD	TCGA;ICGC;COSMIC	5.604	Up-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q9BQG0	MYBBP1A	O14757	CHEK1	T637	R633C	633	Missense	distal	-4	no	6.856	6.482	EPSD	TCGA;ICGC	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q9BQG0	MYBBP1A	O14757	CHEK1	S698	E701Q	701	Missense	distal	3	no	7.415	7.015	EPSD	TCGA;ICGC;COSMIC	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q9BQG0	MYBBP1A	O14757	CHEK1	S775	E780K	780	Missense	distal	5	no	8.939	8.874	EPSD	TCGA;ICGC;COSMIC	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q9BQG0	MYBBP1A	O14757	CHEK1	S979	L982P	982	Missense	distal	3	no	8.367	9.130	EPSD	TCGA;ICGC;COSMIC	5.604	Up-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q9BQG0	MYBBP1A	O14757	CHEK1	S979	T975S	975	Missense	distal	-4	no	8.367	8.418	EPSD	TCGA;ICGC;COSMIC	5.604	Up-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q9BQG0	MYBBP1A	O14757	CHEK1	S991	N990Y	990	Missense	proximal	-1	no	7.011	7.121	EPSD	TCGA;ICGC;COSMIC	5.604	Up-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q9BQG0	MYBBP1A	O14757	CHEK1	S991	R989H	989	Missense	proximal	-2	no	7.011	7.075	EPSD	TCGA;ICGC	5.604	Up-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q9BQG0	MYBBP1A	O14757	CHEK1	S991	P996S	996	Missense	distal	5	no	7.011	7.093	EPSD	TCGA;ICGC;COSMIC	5.604	Up-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q9BQG0	MYBBP1A	O14757	CHEK1	S991	V995I	995	Missense	distal	4	no	7.011	6.951	EPSD	TCGA;ICGC;COSMIC	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q9BQG0	MYBBP1A	O14757	CHEK1	S1000	H1005R	1005	Missense	distal	5	no	6.898	6.882	EPSD	TCGA;ICGC;COSMIC	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q9BQG0	MYBBP1A	O14757	CHEK1	S1000	P1006L	1006	Missense	distal	6	no	6.898	6.688	EPSD	TCGA;ICGC;COSMIC	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q9BQG0	MYBBP1A	O14757	CHEK1	S1000	P996S	996	Missense	distal	-4	no	6.898	6.662	EPSD	TCGA;ICGC;COSMIC	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q9BQG0	MYBBP1A	O14757	CHEK1	S1000	V995I	995	Missense	distal	-5	no	6.898	8.344	EPSD	TCGA;ICGC;COSMIC	5.604	Up-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q9BQG0	MYBBP1A	O14757	CHEK1	S1243	A1246T	1246	Missense	distal	3	no	8.906	8.668	EPSD	TCGA;ICGC;COSMIC	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q9BQG0	MYBBP1A	O14757	CHEK1	S1310	S1314N	1314	Missense	distal	4	no	10.671	10.691	PhosphoSitePlus	TCGA;ICGC;COSMIC	5.604	Up-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q9BQG0	MYBBP1A	O14757	CHEK1	S1310	A1316V	1316	Missense	distal	6	no	10.671	10.559	PhosphoSitePlus	TCGA;ICGC;COSMIC	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q9BQG0	MYBBP1A	O14757	CHEK1	S1310	S1310N	1310	Missense	central	0	yes	10.671	0.000	PhosphoSitePlus	TCGA;ICGC;COSMIC	5.604	Loss
CAMK_CAMKL_CHK1_CHEK1_ST	Q9BQG0	MYBBP1A	O14757	CHEK1	S1310	P1309T	1309	Missense	proximal	-1	no	10.671	10.429	PhosphoSitePlus	TCGA;ICGC;COSMIC	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q9HC62	SENP2	O14757	CHEK1	S32	L36V	36	Missense	distal	4	no	14.222	14.296	EPSD	TCGA;COSMIC	5.604	Up-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q9HC62	SENP2	O14757	CHEK1	S32	D33G	33	Missense	proximal	1	no	14.222	14.134	EPSD	TCGA;ICGC;COSMIC	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q9HC62	SENP2	O14757	CHEK1	S34	L36V	36	Missense	proximal	2	no	10.144	10.431	EPSD	TCGA;COSMIC	5.604	Up-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q9HC62	SENP2	O14757	CHEK1	S34	D33G	33	Missense	proximal	-1	no	10.144	10.193	EPSD	TCGA;ICGC;COSMIC	5.604	Up-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q9HC62	SENP2	O14757	CHEK1	S168	R166H	166	Missense	proximal	-2	no	11.559	11.623	EPSD	TCGA;ICGC;COSMIC	5.604	Up-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q9HC62	SENP2	O14757	CHEK1	S333	S326L	326	Missense	distal	-7	no	11.612	10.728	EPSD	TCGA;COSMIC	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q9HC62	SENP2	O14757	CHEK1	S333	G332R	332	Missense	proximal	-1	no	11.612	11.595	EPSD	TCGA;COSMIC	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q9HC62	SENP2	O14757	CHEK1	S333	R330C	330	Missense	distal	-3	no	11.612	3.520	EPSD	TCGA;COSMIC	5.604	Loss
CAMK_CAMKL_CHK1_CHEK1_ST	Q9HC62	SENP2	O14757	CHEK1	S335	G332R	332	Missense	distal	-3	no	2.156	9.930	EPSD	TCGA;COSMIC	5.604	Gain
CAMK_CAMKL_CHK1_CHEK1_ST	Q9HC62	SENP2	O14757	CHEK1	S344	I345V	345	Missense	proximal	1	no	12.074	12.103	PhosphoSitePlus	TCGA;COSMIC	5.604	Up-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q9HC62	SENP2	O14757	CHEK1	S344	K351N	351	Missense	distal	7	no	12.074	12.136	PhosphoSitePlus	TCGA;COSMIC	5.604	Up-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q9HC62	SENP2	O14757	CHEK1	S344	I346L	346	Missense	proximal	2	no	12.074	12.186	PhosphoSitePlus	TCGA;COSMIC	5.604	Up-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q08AD1	CAMSAP2	O14757	CHEK1	S687	S688G	688	Missense	proximal	1	no	7.151	7.168	EPSD	TCGA;ICGC;COSMIC	5.604	Up-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q08AD1	CAMSAP2	O14757	CHEK1	S980	R976K	976	Missense	distal	-4	no	6.922	7.023	EPSD	TCGA;COSMIC	5.604	Up-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q08AD1	CAMSAP2	O14757	CHEK1	S1019	P1013S	1013	Missense	distal	-6	no	8.023	7.925	EPSD	TCGA;ICGC;COSMIC	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q9Y3Y2	CHTOP	O14757	CHEK1	T33	T33M	33	Missense	central	0	yes	7.189	0.000	EPSD	TCGA;COSMIC;GDSC;CCLE	5.604	Loss
CAMK_CAMKL_CHK1_CHEK1_ST	Q9Y3Y2	CHTOP	O14757	CHEK1	T33	L27R	27	Missense	distal	-6	no	7.189	7.085	EPSD	TCGA;COSMIC	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q9Y3Y2	CHTOP	O14757	CHEK1	T33	K28N	28	Missense	distal	-5	no	7.189	6.295	EPSD	TCGA;ICGC	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q9Y3Y2	CHTOP	O14757	CHEK1	T33	P32L	32	Missense	proximal	-1	no	7.189	7.003	EPSD	TCGA;ICGC;COSMIC	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	P30305	CDC25B	O14757	CHEK1	S151	P153L	153	Missense	proximal	2	no	9.075	8.757	EPSD	TCGA;ICGC;COSMIC	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	P30305	CDC25B	O14757	CHEK1	S151	R148H	148	Missense	distal	-3	no	9.075	3.265	EPSD	TCGA;ICGC	5.604	Loss
CAMK_CAMKL_CHK1_CHEK1_ST	P30305	CDC25B	O14757	CHEK1	T167	S160I	160	Missense	distal	-7	no	7.142	6.499	EPSD	TCGA	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	P30305	CDC25B	O14757	CHEK1	T167	S160C	160	Missense	distal	-7	no	7.142	6.155	EPSD	TCGA;COSMIC	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	P30305	CDC25B	O14757	CHEK1	T167	V162M	162	Missense	distal	-5	no	7.142	6.245	EPSD	TCGA;ICGC;COSMIC	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	P30305	CDC25B	O14757	CHEK1	T167	R164Q	164	Missense	distal	-3	no	7.142	-0.065	EPSD	TCGA	5.604	Loss
CAMK_CAMKL_CHK1_CHEK1_ST	P30305	CDC25B	O14757	CHEK1	S230	A225V	225	Missense	distal	-5	no	9.172	11.612	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	5.604	Up-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	P30305	CDC25B	O14757	CHEK1	S230	Q226H	226	Missense	distal	-4	no	9.172	8.815	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	P30305	CDC25B	O14757	CHEK1	S230	L237I	237	Missense	distal	7	no	9.172	8.888	EPSD;PhosphoSitePlus	TCGA	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	P30305	CDC25B	O14757	CHEK1	S323	R317Q	317	Missense	distal	-6	no	8.657	8.739	EPSD	TCGA;COSMIC	5.604	Up-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	P30305	CDC25B	O14757	CHEK1	S353	E358K	358	Missense	distal	5	no	9.037	8.971	EPSD	TCGA;ICGC;COSMIC	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	P30305	CDC25B	O14757	CHEK1	S353	R352W	352	Missense	proximal	-1	no	9.037	9.154	EPSD	TCGA;ICGC;COSMIC	5.604	Up-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	P30305	CDC25B	O14757	CHEK1	T355	E358K	358	Missense	distal	3	no	7.993	7.177	EPSD	TCGA;ICGC;COSMIC	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	P30305	CDC25B	O14757	CHEK1	T355	R352W	352	Missense	distal	-3	no	7.993	-25.610	EPSD	TCGA;ICGC;COSMIC	5.604	Loss
CAMK_CAMKL_CHK1_CHEK1_ST	P30305	CDC25B	O14757	CHEK1	S375	E380Q	380	Missense	distal	5	no	9.149	9.036	EPSD	TCGA;COSMIC	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	P30305	CDC25B	O14757	CHEK1	S375	S373T	373	Missense	proximal	-2	no	9.149	9.403	EPSD	TCGA;ICGC;COSMIC	5.604	Up-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	P30305	CDC25B	O14757	CHEK1	S375	R369H	369	Missense	distal	-6	no	9.149	9.259	EPSD	TCGA;COSMIC	5.604	Up-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	P30305	CDC25B	O14757	CHEK1	S563	R568W	568	Missense	distal	5	no	6.380	6.211	PhosphoSitePlus;EPSD	TCGA;COSMIC	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	P30305	CDC25B	O14757	CHEK1	S563	R562H	562	Missense	proximal	-1	no	6.380	6.505	PhosphoSitePlus;EPSD	TCGA;COSMIC;CCLE	5.604	Up-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q5JSZ5	PRRC2B	O14757	CHEK1	S31	S37P	37	Missense	distal	6	no	5.019	5.639	EPSD	TCGA;ICGC;COSMIC	5.604	Gain
CAMK_CAMKL_CHK1_CHEK1_ST	Q5JSZ5	PRRC2B	O14757	CHEK1	S37	A34G	34	Missense	distal	-3	no	5.727	4.664	EPSD	TCGA;ICGC;COSMIC	5.604	Loss
CAMK_CAMKL_CHK1_CHEK1_ST	Q5JSZ5	PRRC2B	O14757	CHEK1	S37	A34T	34	Missense	distal	-3	no	5.727	-8.131	EPSD	TCGA;ICGC;COSMIC;GDSC;CCLE	5.604	Loss
CAMK_CAMKL_CHK1_CHEK1_ST	Q5JSZ5	PRRC2B	O14757	CHEK1	S37	S37P	37	Missense	central	0	yes	5.727	0.000	EPSD	TCGA;ICGC;COSMIC	5.604	Loss
CAMK_CAMKL_CHK1_CHEK1_ST	Q5JSZ5	PRRC2B	O14757	CHEK1	S37	R42I	42	Missense	distal	5	no	5.727	5.687	EPSD	TCGA;ICGC	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q5JSZ5	PRRC2B	O14757	CHEK1	S104	Q105E	105	Missense	proximal	1	no	5.996	6.062	EPSD	TCGA;ICGC;COSMIC	5.604	Up-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q5JSZ5	PRRC2B	O14757	CHEK1	S104	P107L	107	Missense	distal	3	no	5.996	5.233	EPSD	TCGA;ICGC;COSMIC	5.604	Loss
CAMK_CAMKL_CHK1_CHEK1_ST	Q5JSZ5	PRRC2B	O14757	CHEK1	S104	S109L	109	Missense	distal	5	no	5.996	5.752	EPSD	TCGA;ICGC	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q5JSZ5	PRRC2B	O14757	CHEK1	S120	P125L	125	Missense	distal	5	no	8.802	8.640	EPSD	TCGA;ICGC	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q5JSZ5	PRRC2B	O14757	CHEK1	S166	F167L	167	Missense	proximal	1	no	9.677	9.673	PhosphoSitePlus	TCGA;ICGC;COSMIC	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q5JSZ5	PRRC2B	O14757	CHEK1	S166	R163G	163	Missense	distal	-3	no	9.677	1.902	PhosphoSitePlus	TCGA;ICGC;COSMIC	5.604	Loss
CAMK_CAMKL_CHK1_CHEK1_ST	Q5JSZ5	PRRC2B	O14757	CHEK1	S236	R233T	233	Missense	distal	-3	no	12.090	-8.479	EPSD	TCGA;ICGC;COSMIC	5.604	Loss
CAMK_CAMKL_CHK1_CHEK1_ST	Q5JSZ5	PRRC2B	O14757	CHEK1	S480	R477W	477	Missense	distal	-3	no	7.562	-26.041	EPSD	TCGA;ICGC;COSMIC	5.604	Loss
CAMK_CAMKL_CHK1_CHEK1_ST	Q5JSZ5	PRRC2B	O14757	CHEK1	T736	R733T	733	Missense	distal	-3	no	6.742	-13.827	EPSD	TCGA;ICGC;COSMIC	5.604	Loss
CAMK_CAMKL_CHK1_CHEK1_ST	Q5JSZ5	PRRC2B	O14757	CHEK1	T736	P742H	742	Missense	distal	6	no	6.742	6.498	EPSD	TCGA;ICGC;COSMIC	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q5JSZ5	PRRC2B	O14757	CHEK1	T736	I738F	738	Missense	proximal	2	no	6.742	7.104	EPSD	TCGA;ICGC;COSMIC	5.604	Up-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q5JSZ5	PRRC2B	O14757	CHEK1	S778	S781F	781	Missense	distal	3	no	7.062	7.250	EPSD	TCGA;COSMIC	5.604	Up-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q5JSZ5	PRRC2B	O14757	CHEK1	S778	E777Q	777	Missense	proximal	-1	no	7.062	7.168	EPSD	TCGA;ICGC;COSMIC	5.604	Up-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q5JSZ5	PRRC2B	O14757	CHEK1	T895	R892Q	892	Missense	distal	-3	no	6.965	-0.242	EPSD	TCGA;ICGC;GDSC	5.604	Loss
CAMK_CAMKL_CHK1_CHEK1_ST	Q5JSZ5	PRRC2B	O14757	CHEK1	S1132	R1127Q	1127	Missense	distal	-5	no	10.231	9.835	EPSD	TCGA;ICGC;COSMIC	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q5JSZ5	PRRC2B	O14757	CHEK1	S1132	R1128W	1128	Missense	distal	-4	no	10.231	9.469	EPSD	TCGA;COSMIC	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q5JSZ5	PRRC2B	O14757	CHEK1	S1167	D1173V	1173	Missense	distal	6	no	10.017	10.477	EPSD	TCGA;ICGC;COSMIC	5.604	Up-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q5JSZ5	PRRC2B	O14757	CHEK1	S1167	K1170N	1170	Missense	distal	3	no	10.017	10.215	EPSD	TCGA;ICGC	5.604	Up-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q5JSZ5	PRRC2B	O14757	CHEK1	S1167	S1167N	1167	Missense	central	0	yes	10.017	0.000	EPSD	TCGA;ICGC;COSMIC	5.604	Loss
CAMK_CAMKL_CHK1_CHEK1_ST	Q5JSZ5	PRRC2B	O14757	CHEK1	S1167	E1163D	1163	Missense	distal	-4	no	10.017	9.876	EPSD	TCGA;ICGC	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q5JSZ5	PRRC2B	O14757	CHEK1	S1167	S1160L	1160	Missense	distal	-7	no	10.017	9.133	EPSD	TCGA;COSMIC	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q5JSZ5	PRRC2B	O14757	CHEK1	S1235	S1242F	1242	Missense	distal	7	no	5.912	5.482	EPSD	TCGA;ICGC;COSMIC	5.604	Loss
CAMK_CAMKL_CHK1_CHEK1_ST	Q5JSZ5	PRRC2B	O14757	CHEK1	S1422	R1425K	1425	Missense	distal	3	no	9.656	10.303	EPSD	TCGA;ICGC;COSMIC	5.604	Up-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q5JSZ5	PRRC2B	O14757	CHEK1	S1422	R1419W	1419	Missense	distal	-3	no	9.656	-23.947	EPSD	TCGA;ICGC	5.604	Loss
CAMK_CAMKL_CHK1_CHEK1_ST	Q5JSZ5	PRRC2B	O14757	CHEK1	S1458	R1455H	1455	Missense	distal	-3	no	10.513	4.704	EPSD	TCGA;ICGC;COSMIC	5.604	Loss
CAMK_CAMKL_CHK1_CHEK1_ST	Q5JSZ5	PRRC2B	O14757	CHEK1	S1508	E1512K	1512	Missense	distal	4	no	6.461	6.455	EPSD	TCGA;COSMIC	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q5JSZ5	PRRC2B	O14757	CHEK1	S1508	A1515S	1515	Missense	distal	7	no	6.461	6.411	EPSD	TCGA;COSMIC	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q5JSZ5	PRRC2B	O14757	CHEK1	S1595	R1601Q	1601	Missense	distal	6	no	8.712	8.705	EPSD	TCGA;COSMIC	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q5JSZ5	PRRC2B	O14757	CHEK1	S1595	S1595F	1595	Missense	central	0	yes	8.712	0.000	EPSD	TCGA;COSMIC	5.604	Loss
CAMK_CAMKL_CHK1_CHEK1_ST	Q5JSZ5	PRRC2B	O14757	CHEK1	S1595	R1597H	1597	Missense	proximal	2	no	8.712	8.730	EPSD	TCGA;COSMIC	5.604	Up-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q5JSZ5	PRRC2B	O14757	CHEK1	S1858	A1859V	1859	Missense	proximal	1	no	6.978	6.954	EPSD	TCGA;COSMIC	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q5JSZ5	PRRC2B	O14757	CHEK1	S1858	R1860H	1860	Missense	proximal	2	no	6.978	6.997	EPSD	TCGA;COSMIC	5.604	Up-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q5JSZ5	PRRC2B	O14757	CHEK1	S2085	P2079S	2079	Missense	distal	-6	no	11.961	11.864	EPSD	TCGA	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q5JSZ5	PRRC2B	O14757	CHEK1	S2085	G2084S	2084	Missense	proximal	-1	no	11.961	11.783	EPSD	TCGA;COSMIC	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q5JSZ5	PRRC2B	O14757	CHEK1	S2103	S2105F	2105	Missense	proximal	2	no	6.503	6.358	EPSD	TCGA;COSMIC	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q5JSZ5	PRRC2B	O14757	CHEK1	S2103	Q2102H	2102	Missense	proximal	-1	no	6.503	6.613	EPSD	TCGA	5.604	Up-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	P02545	LMNA	O14757	CHEK1	S51	G58R	58	Missense	distal	7	no	9.757	9.752	EPSD	TCGA;ICGC;COSMIC	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	P02545	LMNA	O14757	CHEK1	S51	L52V	52	Missense	proximal	1	no	9.757	9.760	EPSD	TCGA;ICGC;COSMIC	5.604	Up-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	P02545	LMNA	O14757	CHEK1	S51	Y45C	45	Missense	distal	-6	no	9.757	9.631	EPSD	TCGA;ICGC;COSMIC	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	P02545	LMNA	O14757	CHEK1	S75	V69M	69	Missense	distal	-6	no	10.848	10.898	EPSD	TCGA;ICGC;COSMIC	5.604	Up-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	P02545	LMNA	O14757	CHEK1	S75	K78N	78	Missense	distal	3	no	10.848	11.045	EPSD	TCGA;ICGC;COSMIC	5.604	Up-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	P02545	LMNA	O14757	CHEK1	T157	E154K	154	Missense	distal	-3	no	3.684	6.947	EPSD	TCGA;ICGC;COSMIC	5.604	Gain
CAMK_CAMKL_CHK1_CHEK1_ST	P02545	LMNA	O14757	CHEK1	T224	N231S	231	Missense	distal	7	no	10.611	10.381	EPSD	TCGA;COSMIC	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	P02545	LMNA	O14757	CHEK1	T224	D230Y	230	Missense	distal	6	no	10.611	11.536	EPSD	TCGA;COSMIC	5.604	Up-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	P02545	LMNA	O14757	CHEK1	T224	R220H	220	Missense	distal	-4	no	10.611	10.413	EPSD	TCGA	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	P02545	LMNA	O14757	CHEK1	T224	R221H	221	Missense	distal	-3	no	10.611	4.801	EPSD	TCGA;COSMIC	5.604	Loss
CAMK_CAMKL_CHK1_CHEK1_ST	P02545	LMNA	O14757	CHEK1	S268	A274T	274	Missense	distal	6	no	11.876	11.798	EPSD	TCGA	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	P02545	LMNA	O14757	CHEK1	S301	R296H	296	Missense	distal	-5	no	10.314	7.849	EPSD	TCGA;COSMIC	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	P02545	LMNA	O14757	CHEK1	S301	A304T	304	Missense	distal	3	no	10.314	10.077	EPSD	TCGA;COSMIC	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	P02545	LMNA	O14757	CHEK1	S307	A304T	304	Missense	distal	-3	no	7.332	-6.525	PhosphoSitePlus	TCGA;COSMIC	5.604	Loss
CAMK_CAMKL_CHK1_CHEK1_ST	P02545	LMNA	O14757	CHEK1	S404	R399H	399	Missense	distal	-5	no	7.892	5.426	EPSD	TCGA;COSMIC	5.604	Loss
CAMK_CAMKL_CHK1_CHEK1_ST	P02545	LMNA	O14757	CHEK1	S404	R401C	401	Missense	distal	-3	no	7.892	-0.200	EPSD	TCGA;COSMIC	5.604	Loss
CAMK_CAMKL_CHK1_CHEK1_ST	P02545	LMNA	O14757	CHEK1	S458	R453Q	453	Missense	distal	-5	no	9.534	9.138	EPSD	TCGA	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	P02545	LMNA	O14757	CHEK1	S458	R453W	453	Missense	distal	-5	no	9.534	8.675	EPSD	TCGA	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	P02545	LMNA	O14757	CHEK1	S458	S463F	463	Missense	distal	5	no	9.534	9.209	EPSD	TCGA	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	P02545	LMNA	O14757	CHEK1	T585	R584H	584	Missense	proximal	-1	no	6.830	6.956	EPSD	TCGA	5.604	Up-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	P02545	LMNA	O14757	CHEK1	T585	G589R	589	Missense	distal	4	no	6.830	6.814	EPSD	TCGA;COSMIC	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	P02545	LMNA	O14757	CHEK1	T585	S583L	583	Missense	proximal	-2	no	6.830	6.935	EPSD	TCGA;COSMIC	5.604	Up-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	P02545	LMNA	O14757	CHEK1	S657	N660S	660	Missense	distal	3	no	10.155	9.314	EPSD	TCGA;COSMIC	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	O15151	MDM4	O14757	CHEK1	S96	D100N	100	Missense	distal	4	no	6.210	6.179	EPSD	TCGA;ICGC;COSMIC	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	O15151	MDM4	O14757	CHEK1	S127	S132C	132	Missense	distal	5	no	6.492	6.144	EPSD	TCGA;ICGC;COSMIC	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	O15151	MDM4	O14757	CHEK1	S127	Q124H	124	Missense	distal	-3	no	6.492	7.889	EPSD	TCGA;COSMIC	5.604	Up-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	O15151	MDM4	O14757	CHEK1	S127	A123T	123	Missense	distal	-4	no	6.492	6.061	EPSD	TCGA;COSMIC	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	O15151	MDM4	O14757	CHEK1	T150	P156S	156	Missense	distal	6	no	9.666	9.046	EPSD	TCGA;ICGC;COSMIC	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	O15151	MDM4	O14757	CHEK1	T150	D154N	154	Missense	distal	4	no	9.666	9.635	EPSD	TCGA;ICGC;COSMIC;CCLE	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	O15151	MDM4	O14757	CHEK1	S342	T338P	338	Missense	distal	-4	no	8.442	8.730	PhosphoSitePlus;EPSD	TCGA;COSMIC	5.604	Up-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	O15151	MDM4	O14757	CHEK1	S367	V371I	371	Missense	distal	4	no	8.466	8.406	EPSD;PhosphoSitePlus	TCGA;COSMIC	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	O15151	MDM4	O14757	CHEK1	S367	P369S	369	Missense	proximal	2	no	8.466	8.542	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	5.604	Up-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	O95625	ZBTB11	O14757	CHEK1	S130	V132F	132	Missense	proximal	2	no	9.242	9.205	EPSD	TCGA	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	O95625	ZBTB11	O14757	CHEK1	S130	D124H	124	Missense	distal	-6	no	9.242	9.444	EPSD	TCGA;ICGC;COSMIC	5.604	Up-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	O95625	ZBTB11	O14757	CHEK1	S130	R125Q	125	Missense	distal	-5	no	9.242	8.846	EPSD	TCGA;ICGC;COSMIC	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	O95625	ZBTB11	O14757	CHEK1	S130	R127C	127	Missense	distal	-3	no	9.242	1.151	EPSD	TCGA;ICGC;COSMIC	5.604	Loss
CAMK_CAMKL_CHK1_CHEK1_ST	O95625	ZBTB11	O14757	CHEK1	S193	S192Y	192	Missense	proximal	-1	no	5.503	5.832	EPSD	TCGA;ICGC;COSMIC	5.604	Gain
CAMK_CAMKL_CHK1_CHEK1_ST	O95625	ZBTB11	O14757	CHEK1	S442	S435Y	435	Missense	distal	-7	no	5.826	4.168	EPSD	TCGA;ICGC;COSMIC	5.604	Loss
CAMK_CAMKL_CHK1_CHEK1_ST	O95625	ZBTB11	O14757	CHEK1	S442	S448I	448	Missense	distal	6	no	5.826	5.869	EPSD	TCGA;ICGC;COSMIC	5.604	Up-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	O95625	ZBTB11	O14757	CHEK1	S511	R510C	510	Missense	proximal	-1	no	9.371	9.406	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	5.604	Up-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	O95625	ZBTB11	O14757	CHEK1	S511	R506G	506	Missense	distal	-5	no	9.371	9.206	EPSD;PhosphoSitePlus	TCGA;ICGC	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	O95625	ZBTB11	O14757	CHEK1	S537	A533T	533	Missense	distal	-4	no	5.926	5.495	PhosphoSitePlus;EPSD	TCGA;ICGC;COSMIC	5.604	Loss
CAMK_CAMKL_CHK1_CHEK1_ST	O95625	ZBTB11	O14757	CHEK1	S537	V539A	539	Missense	proximal	2	no	5.926	6.489	PhosphoSitePlus;EPSD	TCGA;ICGC;COSMIC	5.604	Up-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	O95625	ZBTB11	O14757	CHEK1	S665	K672N	672	Missense	distal	7	no	6.915	6.977	EPSD	TCGA;ICGC;COSMIC	5.604	Up-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	O95625	ZBTB11	O14757	CHEK1	S665	S665Y	665	Missense	central	0	yes	6.915	0.000	EPSD	TCGA;ICGC;COSMIC	5.604	Loss
CAMK_CAMKL_CHK1_CHEK1_ST	O95625	ZBTB11	O14757	CHEK1	S665	R667Q	667	Missense	proximal	2	no	6.915	7.444	EPSD	TCGA;ICGC;COSMIC;CCLE	5.604	Up-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	O95625	ZBTB11	O14757	CHEK1	S665	T659A	659	Missense	distal	-6	no	6.915	6.720	EPSD	TCGA;ICGC	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q9UPP1	PHF8	O14757	CHEK1	S104	R102C	102	Missense	proximal	-2	no	9.702	9.650	EPSD	TCGA;COSMIC	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q9UPP1	PHF8	O14757	CHEK1	S104	S104F	104	Missense	central	0	yes	9.702	0.000	EPSD	TCGA;COSMIC	5.604	Loss
CAMK_CAMKL_CHK1_CHEK1_ST	Q9UPP1	PHF8	O14757	CHEK1	S104	H111R	111	Missense	distal	7	no	9.702	9.994	EPSD	TCGA;COSMIC	5.604	Up-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q9UPP1	PHF8	O14757	CHEK1	S105	R102C	102	Missense	distal	-3	no	9.913	1.822	EPSD	TCGA;COSMIC	5.604	Loss
CAMK_CAMKL_CHK1_CHEK1_ST	Q9UPP1	PHF8	O14757	CHEK1	S105	S104F	104	Missense	proximal	-1	no	9.913	10.187	EPSD	TCGA;COSMIC	5.604	Up-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q9UPP1	PHF8	O14757	CHEK1	S105	H111R	111	Missense	distal	6	no	9.913	9.625	EPSD	TCGA;COSMIC	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q9UPP1	PHF8	O14757	CHEK1	S621	R616T	616	Missense	distal	-5	no	4.821	5.742	EPSD	TCGA;COSMIC	5.604	Gain
CAMK_CAMKL_CHK1_CHEK1_ST	Q9UPP1	PHF8	O14757	CHEK1	S826	E825K	825	Missense	proximal	-1	no	6.625	6.568	EPSD	TCGA;COSMIC	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q9UPP1	PHF8	O14757	CHEK1	S874	R867Q	867	Missense	distal	-7	no	6.172	6.430	EPSD	TCGA;COSMIC	5.604	Up-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q9UPP1	PHF8	O14757	CHEK1	S874	P878T	878	Missense	distal	4	no	6.172	6.044	EPSD	TCGA;COSMIC	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q9UPP1	PHF8	O14757	CHEK1	S874	K869N	869	Missense	distal	-5	no	6.172	5.279	EPSD	TCGA	5.604	Loss
CAMK_CAMKL_CHK1_CHEK1_ST	Q9UPP1	PHF8	O14757	CHEK1	T900	R894C	894	Missense	distal	-6	no	5.875	5.990	EPSD	TCGA	5.604	Up-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q9UPP1	PHF8	O14757	CHEK1	T900	S904Y	904	Missense	distal	4	no	5.875	6.049	EPSD	TCGA;COSMIC	5.604	Up-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q9UPP1	PHF8	O14757	CHEK1	T900	R901W	901	Missense	proximal	1	no	5.875	5.845	EPSD	TCGA;COSMIC	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q9UPP1	PHF8	O14757	CHEK1	T900	R897H	897	Missense	distal	-3	no	5.875	0.065	EPSD	TCGA;COSMIC	5.604	Loss
CAMK_CAMKL_CHK1_CHEK1_ST	Q9UPP1	PHF8	O14757	CHEK1	S904	S904Y	904	Missense	central	0	yes	10.335	0.000	PhosphoSitePlus	TCGA;COSMIC	5.604	Loss
CAMK_CAMKL_CHK1_CHEK1_ST	Q9UPP1	PHF8	O14757	CHEK1	S904	R901W	901	Missense	distal	-3	no	10.335	-23.268	PhosphoSitePlus	TCGA;COSMIC	5.604	Loss
CAMK_CAMKL_CHK1_CHEK1_ST	Q9UPP1	PHF8	O14757	CHEK1	S904	R897H	897	Missense	distal	-7	no	10.335	10.276	PhosphoSitePlus	TCGA;COSMIC	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q9UPP1	PHF8	O14757	CHEK1	S1021	R1018Q	1018	Missense	distal	-3	no	11.227	4.020	EPSD	TCGA	5.604	Loss
CAMK_CAMKL_CHK1_CHEK1_ST	Q9UPP1	PHF8	O14757	CHEK1	S1021	S1026R	1026	Missense	distal	5	no	11.227	11.123	EPSD	TCGA;ICGC;COSMIC	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q9UPP1	PHF8	O14757	CHEK1	S1021	S1021P	1021	Missense	central	0	yes	11.227	0.000	EPSD	TCGA	5.604	Loss
CAMK_CAMKL_CHK1_CHEK1_ST	Q9UPP1	PHF8	O14757	CHEK1	S1024	S1021P	1021	Missense	distal	-3	no	3.615	6.174	EPSD	TCGA	5.604	Gain
CAMK_CAMKL_CHK1_CHEK1_ST	Q9H0H5	RACGAP1	O14757	CHEK1	T63	R65Q	65	Missense	proximal	2	no	8.710	9.239	EPSD	TCGA;ICGC;COSMIC	5.604	Up-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q9H0H5	RACGAP1	O14757	CHEK1	T145	S151Y	151	Missense	distal	6	no	9.217	9.958	EPSD	TCGA;ICGC;COSMIC	5.604	Up-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q9H0H5	RACGAP1	O14757	CHEK1	S185	R184C	184	Missense	proximal	-1	no	6.899	6.934	EPSD	TCGA;ICGC;COSMIC	5.604	Up-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q9H0H5	RACGAP1	O14757	CHEK1	T186	R184C	184	Missense	proximal	-2	no	9.475	9.424	EPSD	TCGA;ICGC;COSMIC	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q9H0H5	RACGAP1	O14757	CHEK1	T186	S185T	185	Missense	proximal	-1	no	9.475	9.680	EPSD	TCGA;ICGC;COSMIC	5.604	Up-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q9H0H5	RACGAP1	O14757	CHEK1	T186	G193D	193	Missense	distal	7	no	9.475	9.768	EPSD	TCGA;ICGC;COSMIC	5.604	Up-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q9H0H5	RACGAP1	O14757	CHEK1	S187	R184C	184	Missense	distal	-3	no	10.203	2.112	EPSD	TCGA;ICGC;COSMIC	5.604	Loss
CAMK_CAMKL_CHK1_CHEK1_ST	Q9H0H5	RACGAP1	O14757	CHEK1	S187	S185T	185	Missense	proximal	-2	no	10.203	10.457	EPSD	TCGA;ICGC;COSMIC	5.604	Up-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q9H0H5	RACGAP1	O14757	CHEK1	S187	G193D	193	Missense	distal	6	no	10.203	9.807	EPSD	TCGA;ICGC;COSMIC	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q9H0H5	RACGAP1	O14757	CHEK1	S203	Q210H	210	Missense	distal	7	no	6.016	5.569	PhosphoSitePlus	TCGA;ICGC;COSMIC	5.604	Loss
CAMK_CAMKL_CHK1_CHEK1_ST	Q9H0H5	RACGAP1	O14757	CHEK1	S203	R202C	202	Missense	proximal	-1	no	6.016	6.051	PhosphoSitePlus	TCGA;ICGC;COSMIC	5.604	Up-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q9H0H5	RACGAP1	O14757	CHEK1	T272	R269T	269	Missense	distal	-3	no	7.235	-13.334	EPSD	TCGA;ICGC;COSMIC	5.604	Loss
CAMK_CAMKL_CHK1_CHEK1_ST	Q9H0H5	RACGAP1	O14757	CHEK1	T272	V275E	275	Missense	distal	3	no	7.235	8.356	EPSD	TCGA;ICGC;COSMIC	5.604	Up-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q9H0H5	RACGAP1	O14757	CHEK1	S299	I295F	295	Missense	distal	-4	no	7.389	7.127	EPSD	TCGA;ICGC;COSMIC	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q9H0H5	RACGAP1	O14757	CHEK1	S299	P302S	302	Missense	distal	3	no	7.389	7.060	EPSD	TCGA;ICGC;COSMIC	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q9H0H5	RACGAP1	O14757	CHEK1	S299	S299F	299	Missense	central	0	yes	7.389	0.000	EPSD	TCGA;ICGC;COSMIC	5.604	Loss
CAMK_CAMKL_CHK1_CHEK1_ST	Q9H0H5	RACGAP1	O14757	CHEK1	T405	L409V	409	Missense	distal	4	no	7.444	7.518	EPSD	TCGA;ICGC;COSMIC	5.604	Up-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q9H0H5	RACGAP1	O14757	CHEK1	T405	S410C	410	Missense	distal	5	no	7.444	7.097	EPSD	TCGA;ICGC;COSMIC	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q9H0H5	RACGAP1	O14757	CHEK1	T405	E398Q	398	Missense	distal	-7	no	7.444	7.219	EPSD	TCGA;ICGC;COSMIC	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q9H0H5	RACGAP1	O14757	CHEK1	T405	K411N	411	Missense	distal	6	no	7.444	7.578	EPSD	TCGA;ICGC;COSMIC	5.604	Up-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q9H0H5	RACGAP1	O14757	CHEK1	S420	D414G	414	Missense	distal	-6	no	5.456	5.666	EPSD	TCGA;ICGC;COSMIC	5.604	Gain
CAMK_CAMKL_CHK1_CHEK1_ST	Q9H0H5	RACGAP1	O14757	CHEK1	S420	F425V	425	Missense	distal	5	no	5.456	5.695	EPSD	TCGA;ICGC;COSMIC	5.604	Gain
CAMK_CAMKL_CHK1_CHEK1_ST	Q9H0H5	RACGAP1	O14757	CHEK1	S533	V528I	528	Missense	distal	-5	no	9.239	10.684	EPSD	TCGA;ICGC;COSMIC	5.604	Up-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q9H0H5	RACGAP1	O14757	CHEK1	S533	R530C	530	Missense	distal	-3	no	9.239	1.148	EPSD	TCGA;ICGC;COSMIC	5.604	Loss
CAMK_CAMKL_CHK1_CHEK1_ST	Q9H0H5	RACGAP1	O14757	CHEK1	S590	R597K	597	Missense	distal	7	no	8.547	8.622	EPSD	TCGA;ICGC	5.604	Up-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q9H0H5	RACGAP1	O14757	CHEK1	S600	P607L	607	Missense	distal	7	no	9.329	9.266	EPSD	TCGA;ICGC;COSMIC	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q9H0H5	RACGAP1	O14757	CHEK1	S600	R597K	597	Missense	distal	-3	no	9.329	5.504	EPSD	TCGA;ICGC	5.604	Loss
CAMK_CAMKL_CHK1_CHEK1_ST	Q9H0H5	RACGAP1	O14757	CHEK1	S611	S613T	613	Missense	proximal	2	no	8.941	8.549	EPSD	TCGA;ICGC;COSMIC	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q9H0H5	RACGAP1	O14757	CHEK1	S611	P607L	607	Missense	distal	-4	no	8.941	8.756	EPSD	TCGA;ICGC;COSMIC	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q9H0H5	RACGAP1	O14757	CHEK1	S611	S613N	613	Missense	proximal	2	no	8.941	9.122	EPSD	TCGA;ICGC;COSMIC	5.604	Up-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q9UMR2	DDX19B	O14757	CHEK1	S93	R98Q	98	Missense	distal	5	no	7.232	7.307	PhosphoSitePlus	TCGA;ICGC;COSMIC	5.604	Up-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q9UMR2	DDX19B	O14757	CHEK1	S347	C340R	340	Missense	distal	-7	no	7.002	7.730	EPSD	TCGA	5.604	Up-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q9UMR2	DDX19B	O14757	CHEK1	S354	V360L	360	Missense	distal	6	no	8.920	9.054	EPSD	TCGA;COSMIC	5.604	Up-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q9UMR2	DDX19B	O14757	CHEK1	T468	E473K	473	Missense	distal	5	no	11.433	11.367	EPSD	TCGA;COSMIC	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q9UMR2	DDX19B	O14757	CHEK1	T468	D469Y	469	Missense	proximal	1	no	11.433	11.310	EPSD	TCGA	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q86UE8	TLK2	O14757	CHEK1	S34	N31K	31	Missense	distal	-3	no	0.376	6.919	EPSD	TCGA;ICGC;COSMIC	5.604	Gain
CAMK_CAMKL_CHK1_CHEK1_ST	Q86UE8	TLK2	O14757	CHEK1	S46	G43R	43	Missense	distal	-3	no	2.773	10.548	EPSD	TCGA;ICGC;COSMIC;CCLE	5.604	Gain
CAMK_CAMKL_CHK1_CHEK1_ST	Q86UE8	TLK2	O14757	CHEK1	S115	P119L	119	Missense	distal	4	no	5.865	5.761	EPSD	TCGA;ICGC;COSMIC	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q86UE8	TLK2	O14757	CHEK1	S115	P121L	121	Missense	distal	6	no	5.865	5.655	EPSD	TCGA;ICGC;COSMIC	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q86UE8	TLK2	O14757	CHEK1	S196	S194F	194	Missense	proximal	-2	no	5.326	5.616	EPSD	TCGA;COSMIC	5.604	Gain
CAMK_CAMKL_CHK1_CHEK1_ST	Q86UE8	TLK2	O14757	CHEK1	T268	K272N	272	Missense	distal	4	no	13.094	13.162	EPSD	TCGA	5.604	Up-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q92974	ARHGEF2	O14757	CHEK1	T103	A97V	97	Missense	distal	-6	no	9.192	9.330	EPSD	TCGA;ICGC;COSMIC	5.604	Up-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q92974	ARHGEF2	O14757	CHEK1	T103	A96T	96	Missense	distal	-7	no	9.192	7.876	EPSD	TCGA	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q92974	ARHGEF2	O14757	CHEK1	S122	P120L	120	Missense	proximal	-2	no	6.578	6.399	EPSD	TCGA;COSMIC	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q92974	ARHGEF2	O14757	CHEK1	S122	P126S	126	Missense	distal	4	no	6.578	6.438	EPSD	TCGA;COSMIC	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q92974	ARHGEF2	O14757	CHEK1	S122	R117Q	117	Missense	distal	-5	no	6.578	6.182	EPSD	TCGA;COSMIC	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q92974	ARHGEF2	O14757	CHEK1	S142	R139H	139	Missense	distal	-3	no	6.650	0.841	EPSD	TCGA;ICGC;COSMIC	5.604	Loss
CAMK_CAMKL_CHK1_CHEK1_ST	Q92974	ARHGEF2	O14757	CHEK1	S172	R168C	168	Missense	distal	-4	no	10.777	10.404	PhosphoSitePlus	TCGA;ICGC;COSMIC	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q92974	ARHGEF2	O14757	CHEK1	S172	S174F	174	Missense	proximal	2	no	10.777	10.633	PhosphoSitePlus	TCGA;COSMIC;CCLE	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q92974	ARHGEF2	O14757	CHEK1	T184	R183Q	183	Missense	proximal	-1	no	10.615	10.631	EPSD	TCGA;COSMIC	5.604	Up-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q92974	ARHGEF2	O14757	CHEK1	T184	T184I	184	Missense	central	0	yes	10.615	0.000	EPSD	TCGA;COSMIC	5.604	Loss
CAMK_CAMKL_CHK1_CHEK1_ST	Q92974	ARHGEF2	O14757	CHEK1	S186	R183Q	183	Missense	distal	-3	no	7.012	-0.194	EPSD	TCGA;COSMIC	5.604	Loss
CAMK_CAMKL_CHK1_CHEK1_ST	Q92974	ARHGEF2	O14757	CHEK1	S186	T184I	184	Missense	proximal	-2	no	7.012	6.886	EPSD	TCGA;COSMIC	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q92974	ARHGEF2	O14757	CHEK1	T258	R262C	262	Missense	distal	4	no	6.469	6.573	EPSD	TCGA;COSMIC	5.604	Up-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q92974	ARHGEF2	O14757	CHEK1	T258	T258I	258	Missense	central	0	yes	6.469	0.000	EPSD	TCGA;COSMIC	5.604	Loss
CAMK_CAMKL_CHK1_CHEK1_ST	Q92974	ARHGEF2	O14757	CHEK1	T258	T263M	263	Missense	distal	5	no	6.469	6.580	EPSD	TCGA;COSMIC;CCLE	5.604	Up-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q92974	ARHGEF2	O14757	CHEK1	T258	R262H	262	Missense	distal	4	no	6.469	6.630	EPSD	TCGA;CCLE	5.604	Up-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q92974	ARHGEF2	O14757	CHEK1	T258	R259H	259	Missense	proximal	1	no	6.469	6.404	EPSD	TCGA;COSMIC	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q92974	ARHGEF2	O14757	CHEK1	T455	R452W	452	Missense	distal	-3	no	7.432	-26.171	EPSD	TCGA;COSMIC	5.604	Loss
CAMK_CAMKL_CHK1_CHEK1_ST	Q92974	ARHGEF2	O14757	CHEK1	T455	P456S	456	Missense	proximal	1	no	7.432	7.469	EPSD	TCGA;COSMIC	5.604	Up-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q92974	ARHGEF2	O14757	CHEK1	T455	P451T	451	Missense	distal	-4	no	7.432	7.145	EPSD	TCGA;COSMIC	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q92974	ARHGEF2	O14757	CHEK1	S645	R650C	650	Missense	distal	5	no	10.882	10.638	EPSD	TCGA;COSMIC;CCLE	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q92974	ARHGEF2	O14757	CHEK1	S645	L640V	640	Missense	distal	-5	no	10.882	7.405	EPSD	TCGA;COSMIC	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q92974	ARHGEF2	O14757	CHEK1	S645	R638S	638	Missense	distal	-7	no	10.882	11.141	EPSD	TCGA;COSMIC	5.604	Up-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q92974	ARHGEF2	O14757	CHEK1	S719	R724T	724	Missense	distal	5	no	10.291	10.172	EPSD	TCGA;COSMIC	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q92974	ARHGEF2	O14757	CHEK1	S782	R783W	783	Missense	proximal	1	no	11.920	11.891	EPSD	TCGA;COSMIC	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q92974	ARHGEF2	O14757	CHEK1	T802	P797S	797	Missense	distal	-5	no	4.422	5.941	EPSD	TCGA;COSMIC	5.604	Gain
CAMK_CAMKL_CHK1_CHEK1_ST	Q92974	ARHGEF2	O14757	CHEK1	S886	A889T	889	Missense	distal	3	no	10.562	10.325	EPSD	TCGA;COSMIC	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q92974	ARHGEF2	O14757	CHEK1	S886	D891N	891	Missense	distal	5	no	10.562	10.473	EPSD	TCGA;COSMIC	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q92974	ARHGEF2	O14757	CHEK1	S886	R885H	885	Missense	proximal	-1	no	10.562	10.688	EPSD	TCGA;COSMIC	5.604	Up-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q92974	ARHGEF2	O14757	CHEK1	S886	R883W	883	Missense	distal	-3	no	10.562	-23.041	EPSD	TCGA;COSMIC	5.604	Loss
CAMK_CAMKL_CHK1_CHEK1_ST	Q92974	ARHGEF2	O14757	CHEK1	S956	S953R	953	Missense	distal	-3	no	-3.780	5.916	EPSD	TCGA;COSMIC	5.604	Gain
CAMK_CAMKL_CHK1_CHEK1_ST	Q92974	ARHGEF2	O14757	CHEK1	S960	R966T	966	Missense	distal	6	no	6.584	6.807	EPSD	TCGA;COSMIC	5.604	Up-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q92974	ARHGEF2	O14757	CHEK1	S960	S953R	953	Missense	distal	-7	no	6.584	6.324	EPSD	TCGA;COSMIC	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q92974	ARHGEF2	O14757	CHEK1	S960	R954H	954	Missense	distal	-6	no	6.584	6.693	EPSD	TCGA;COSMIC	5.604	Up-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q92974	ARHGEF2	O14757	CHEK1	S960	R954C	954	Missense	distal	-6	no	6.584	6.699	EPSD	TCGA;COSMIC	5.604	Up-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q92974	ARHGEF2	O14757	CHEK1	S960	S960N	960	Missense	central	0	yes	6.584	0.000	EPSD	TCGA;COSMIC	5.604	Loss
CAMK_CAMKL_CHK1_CHEK1_ST	Q92974	ARHGEF2	O14757	CHEK1	T965	R966T	966	Missense	proximal	1	no	5.668	5.650	EPSD	TCGA;COSMIC	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q92974	ARHGEF2	O14757	CHEK1	T965	S960N	960	Missense	distal	-5	no	5.668	6.161	EPSD	TCGA;COSMIC	5.604	Up-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q9Y570	PPME1	O14757	CHEK1	S42	Q48R	48	Missense	distal	6	no	9.468	9.475	EPSD	TCGA;ICGC;COSMIC	5.604	Up-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q9Y570	PPME1	O14757	CHEK1	S42	R39W	39	Missense	distal	-3	no	9.468	-24.135	EPSD	TCGA;ICGC	5.604	Loss
CAMK_CAMKL_CHK1_CHEK1_ST	Q9Y570	PPME1	O14757	CHEK1	S306	G300S	300	Missense	distal	-6	no	8.610	8.572	EPSD	TCGA;ICGC;COSMIC;GDSC;CCLE	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q9Y570	PPME1	O14757	CHEK1	S306	C312Y	312	Missense	distal	6	no	8.610	8.970	EPSD	TCGA;ICGC;COSMIC	5.604	Up-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q9Y570	PPME1	O14757	CHEK1	S306	L308F	308	Missense	proximal	2	no	8.610	8.860	EPSD	TCGA;ICGC	5.604	Up-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	P27816	MAP4	O14757	CHEK1	S68	P66L	66	Missense	proximal	-2	no	6.283	6.104	EPSD	TCGA;ICGC;COSMIC	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	P27816	MAP4	O14757	CHEK1	S68	P66S	66	Missense	proximal	-2	no	6.283	5.999	EPSD	TCGA;ICGC;COSMIC	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	P27816	MAP4	O14757	CHEK1	T324	S330L	330	Missense	distal	6	no	8.033	8.443	EPSD	TCGA;ICGC;COSMIC	5.604	Up-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	P27816	MAP4	O14757	CHEK1	T324	E325G	325	Missense	proximal	1	no	8.033	7.950	EPSD	TCGA;ICGC;COSMIC	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	P27816	MAP4	O14757	CHEK1	T451	T456S	456	Missense	distal	5	no	9.226	9.448	EPSD	TCGA;ICGC;COSMIC	5.604	Up-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	P27816	MAP4	O14757	CHEK1	T451	E455D	455	Missense	distal	4	no	9.226	9.318	EPSD	TCGA;ICGC;COSMIC	5.604	Up-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	P27816	MAP4	O14757	CHEK1	T451	T451P	451	Missense	central	0	yes	9.226	0.000	EPSD	TCGA;ICGC	5.604	Loss
CAMK_CAMKL_CHK1_CHEK1_ST	P27816	MAP4	O14757	CHEK1	S602	S605F	605	Missense	distal	3	no	8.609	8.798	EPSD	TCGA;ICGC;COSMIC	5.604	Up-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	P27816	MAP4	O14757	CHEK1	S602	A595T	595	Missense	distal	-7	no	8.609	7.293	EPSD	TCGA;ICGC	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	P27816	MAP4	O14757	CHEK1	S602	D604E	604	Missense	proximal	2	no	8.609	8.692	EPSD	TCGA;ICGC;COSMIC	5.604	Up-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	P27816	MAP4	O14757	CHEK1	S602	H606R	606	Missense	distal	4	no	8.609	8.448	EPSD	TCGA;ICGC;COSMIC	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	P27816	MAP4	O14757	CHEK1	S609	H606R	606	Missense	distal	-3	no	2.469	8.279	EPSD	TCGA;ICGC;COSMIC	5.604	Gain
CAMK_CAMKL_CHK1_CHEK1_ST	P27816	MAP4	O14757	CHEK1	S801	K802N	802	Missense	proximal	1	no	6.145	6.116	EPSD	TCGA;ICGC;COSMIC	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	P27816	MAP4	O14757	CHEK1	S863	R860H	860	Missense	distal	-3	no	11.041	5.231	EPSD	TCGA;ICGC;GDSC	5.604	Loss
CAMK_CAMKL_CHK1_CHEK1_ST	P27816	MAP4	O14757	CHEK1	T900	R897W	897	Missense	distal	-3	no	5.698	-27.905	EPSD	TCGA;ICGC;COSMIC	5.604	Loss
CAMK_CAMKL_CHK1_CHEK1_ST	P27816	MAP4	O14757	CHEK1	T909	P902H	902	Missense	distal	-7	no	7.205	7.556	EPSD	TCGA;ICGC	5.604	Up-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	P27816	MAP4	O14757	CHEK1	S915	L920H	920	Missense	distal	5	no	6.537	6.694	EPSD	TCGA;ICGC;COSMIC	5.604	Up-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	P27816	MAP4	O14757	CHEK1	T925	L920H	920	Missense	distal	-5	no	7.980	2.538	PhosphoSitePlus	TCGA;ICGC;COSMIC	5.604	Loss
CAMK_CAMKL_CHK1_CHEK1_ST	P27816	MAP4	O14757	CHEK1	S941	K938N	938	Missense	distal	-3	no	7.208	0.665	EPSD	TCGA;ICGC;COSMIC	5.604	Loss
CAMK_CAMKL_CHK1_CHEK1_ST	P27816	MAP4	O14757	CHEK1	S996	H1003Y	1003	Missense	distal	7	no	5.698	5.383	EPSD	TCGA;ICGC;COSMIC	5.604	Loss
CAMK_CAMKL_CHK1_CHEK1_ST	P27816	MAP4	O14757	CHEK1	S1037	N1044S	1044	Missense	distal	7	no	7.338	7.109	EPSD	TCGA;ICGC;COSMIC	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	P27816	MAP4	O14757	CHEK1	S1041	N1044S	1044	Missense	distal	3	no	8.448	7.607	EPSD	TCGA;ICGC;COSMIC	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	P27816	MAP4	O14757	CHEK1	S1073	G1078S	1078	Missense	distal	5	no	7.338	7.529	EPSD	TCGA;ICGC;COSMIC	5.604	Up-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	P27816	MAP4	O14757	CHEK1	S1073	V1071M	1071	Missense	proximal	-2	no	7.338	7.289	EPSD	TCGA;ICGC;COSMIC	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q9UK53	ING1	O14757	CHEK1	S306	E303K	303	Missense	distal	-3	no	2.813	6.076	EPSD	TCGA;COSMIC	5.604	Gain
CAMK_CAMKL_CHK1_CHEK1_ST	Q9UK53	ING1	O14757	CHEK1	S342	A337V	337	Missense	distal	-5	no	8.514	10.954	EPSD	TCGA	5.604	Up-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q9UK53	ING1	O14757	CHEK1	S342	A335V	335	Missense	distal	-7	no	8.514	7.858	EPSD	TCGA;COSMIC	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q9UK53	ING1	O14757	CHEK1	S342	L346I	346	Missense	distal	4	no	8.514	8.529	EPSD	TCGA	5.604	Up-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	O43395	PRPF3	O14757	CHEK1	S174	E179K	179	Missense	distal	5	no	8.206	8.141	EPSD	TCGA;COSMIC	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	O43395	PRPF3	O14757	CHEK1	S174	K171N	171	Missense	distal	-3	no	8.206	1.663	EPSD	TCGA;COSMIC	5.604	Loss
CAMK_CAMKL_CHK1_CHEK1_ST	O43395	PRPF3	O14757	CHEK1	S174	P173S	173	Missense	proximal	-1	no	8.206	7.759	EPSD	TCGA;COSMIC	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	O43395	PRPF3	O14757	CHEK1	S174	P173L	173	Missense	proximal	-1	no	8.206	8.020	EPSD	TCGA;COSMIC	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	O43395	PRPF3	O14757	CHEK1	S174	R180Q	180	Missense	distal	6	no	8.206	8.199	EPSD	TCGA;COSMIC	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	O43395	PRPF3	O14757	CHEK1	T186	E179K	179	Missense	distal	-7	no	5.039	5.737	EPSD	TCGA;COSMIC	5.604	Gain
CAMK_CAMKL_CHK1_CHEK1_ST	O43395	PRPF3	O14757	CHEK1	S307	D304H	304	Missense	distal	-3	no	2.865	6.392	EPSD	TCGA;COSMIC	5.604	Gain
CAMK_CAMKL_CHK1_CHEK1_ST	O43395	PRPF3	O14757	CHEK1	S552	K556T	556	Missense	distal	4	no	7.654	7.713	EPSD	TCGA;COSMIC	5.604	Up-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	O43395	PRPF3	O14757	CHEK1	S552	R549Q	549	Missense	distal	-3	no	7.654	0.447	EPSD	TCGA;COSMIC	5.604	Loss
CAMK_CAMKL_CHK1_CHEK1_ST	O43395	PRPF3	O14757	CHEK1	S552	L551V	551	Missense	proximal	-1	no	7.654	7.648	EPSD	TCGA;COSMIC	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q00341	HDLBP	O14757	CHEK1	T149	R146T	146	Missense	distal	-3	no	6.467	-14.101	EPSD	TCGA;COSMIC	5.604	Loss
CAMK_CAMKL_CHK1_CHEK1_ST	Q00341	HDLBP	O14757	CHEK1	T149	A145V	145	Missense	distal	-4	no	6.467	6.388	EPSD	TCGA;COSMIC	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q00341	HDLBP	O14757	CHEK1	T149	A156V	156	Missense	distal	7	no	6.467	6.547	EPSD	TCGA;ICGC;COSMIC	5.604	Up-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q00341	HDLBP	O14757	CHEK1	S611	R608S	608	Missense	distal	-3	no	10.896	1.200	EPSD	TCGA;ICGC;COSMIC	5.604	Loss
CAMK_CAMKL_CHK1_CHEK1_ST	Q00341	HDLBP	O14757	CHEK1	S622	E620D	620	Missense	proximal	-2	no	6.131	6.117	EPSD	TCGA;ICGC;COSMIC	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q00341	HDLBP	O14757	CHEK1	S622	E625Q	625	Missense	distal	3	no	6.131	5.731	EPSD	TCGA;ICGC;COSMIC	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q00341	HDLBP	O14757	CHEK1	S622	I627F	627	Missense	distal	5	no	6.131	5.949	EPSD	TCGA	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q00341	HDLBP	O14757	CHEK1	S645	S645F	645	Missense	central	0	yes	13.038	0.000	EPSD	TCGA;ICGC;COSMIC	5.604	Loss
CAMK_CAMKL_CHK1_CHEK1_ST	Q00341	HDLBP	O14757	CHEK1	S645	R640W	640	Missense	distal	-5	no	13.038	12.179	EPSD	TCGA;ICGC;COSMIC	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q00341	HDLBP	O14757	CHEK1	S706	R703M	703	Missense	distal	-3	no	10.384	5.235	EPSD	TCGA;ICGC;COSMIC	5.604	Loss
CAMK_CAMKL_CHK1_CHEK1_ST	Q00341	HDLBP	O14757	CHEK1	S706	V700I	700	Missense	distal	-6	no	10.384	10.370	EPSD	TCGA;ICGC;COSMIC	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q00341	HDLBP	O14757	CHEK1	T757	R751C	751	Missense	distal	-6	no	9.881	9.997	EPSD	TCGA;ICGC;COSMIC	5.604	Up-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q00341	HDLBP	O14757	CHEK1	T757	R754C	754	Missense	distal	-3	no	9.881	1.790	EPSD	TCGA;ICGC;COSMIC	5.604	Loss
CAMK_CAMKL_CHK1_CHEK1_ST	Q00341	HDLBP	O14757	CHEK1	T757	K752N	752	Missense	distal	-5	no	9.881	8.988	EPSD	TCGA	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q00341	HDLBP	O14757	CHEK1	T757	R760C	760	Missense	distal	3	no	9.881	8.934	EPSD	TCGA;ICGC;COSMIC	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q00341	HDLBP	O14757	CHEK1	T757	V761A	761	Missense	distal	4	no	9.881	9.964	EPSD	TCGA;ICGC	5.604	Up-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q00341	HDLBP	O14757	CHEK1	T842	T848A	848	Missense	distal	6	no	9.276	9.354	EPSD	TCGA;ICGC;COSMIC	5.604	Up-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q00341	HDLBP	O14757	CHEK1	S904	F909L	909	Missense	distal	5	no	11.035	11.117	EPSD	TCGA;ICGC;COSMIC	5.604	Up-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q00341	HDLBP	O14757	CHEK1	S1245	P1251L	1251	Missense	distal	6	no	7.392	7.182	EPSD	TCGA;ICGC;COSMIC	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q00341	HDLBP	O14757	CHEK1	S1245	E1248G	1248	Missense	distal	3	no	7.392	5.845	EPSD	TCGA;ICGC;COSMIC	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q00341	HDLBP	O14757	CHEK1	S1245	F1250L	1250	Missense	distal	5	no	7.392	7.473	EPSD	TCGA;ICGC;COSMIC	5.604	Up-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q86WR7	PROSER2	O14757	CHEK1	S27	G30S	30	Missense	distal	3	no	7.358	7.445	EPSD	TCGA;ICGC;COSMIC	5.604	Up-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q86WR7	PROSER2	O14757	CHEK1	S31	G30S	30	Missense	proximal	-1	no	5.817	5.639	EPSD	TCGA;ICGC;COSMIC	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q86WR7	PROSER2	O14757	CHEK1	S38	R40C	40	Missense	proximal	2	no	6.454	6.188	EPSD	TCGA;ICGC;COSMIC;GDSC;CCLE	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q86WR7	PROSER2	O14757	CHEK1	S43	R40C	40	Missense	distal	-3	no	9.852	1.760	PhosphoSitePlus	TCGA;ICGC;COSMIC;GDSC;CCLE	5.604	Loss
CAMK_CAMKL_CHK1_CHEK1_ST	Q86WR7	PROSER2	O14757	CHEK1	T45	R40C	40	Missense	distal	-5	no	10.315	9.637	EPSD	TCGA;ICGC;COSMIC;GDSC;CCLE	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q86WR7	PROSER2	O14757	CHEK1	S179	A177P	177	Missense	proximal	-2	no	7.143	7.313	EPSD	TCGA;ICGC;COSMIC	5.604	Up-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q14004	CDK13	O14757	CHEK1	S285	S291L	291	Missense	distal	6	no	11.317	11.727	EPSD	TCGA	5.604	Up-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q14004	CDK13	O14757	CHEK1	S325	S332C	332	Missense	distal	7	no	8.291	7.978	EPSD	TCGA;ICGC;COSMIC	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q14004	CDK13	O14757	CHEK1	S342	L335M	335	Missense	distal	-7	no	5.769	6.253	EPSD	TCGA;ICGC;COSMIC	5.604	Up-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q14004	CDK13	O14757	CHEK1	S369	Y376H	376	Missense	distal	7	no	7.734	8.048	EPSD	TCGA;ICGC;COSMIC	5.604	Up-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q14004	CDK13	O14757	CHEK1	S375	Y376H	376	Missense	proximal	1	no	8.517	8.495	EPSD	TCGA;ICGC;COSMIC	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q14004	CDK13	O14757	CHEK1	S397	S400I	400	Missense	distal	3	no	8.338	7.963	EPSD	TCGA;ICGC	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q14004	CDK13	O14757	CHEK1	S397	R393H	393	Missense	distal	-4	no	8.338	8.140	EPSD	TCGA;ICGC;COSMIC	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q14004	CDK13	O14757	CHEK1	S397	S390N	390	Missense	distal	-7	no	8.338	7.800	EPSD	TCGA;ICGC;COSMIC	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q14004	CDK13	O14757	CHEK1	S413	Y415H	415	Missense	proximal	2	no	7.332	7.552	EPSD	TCGA;ICGC;COSMIC	5.604	Up-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q14004	CDK13	O14757	CHEK1	S433	P440S	440	Missense	distal	7	no	11.421	11.365	EPSD	TCGA;ICGC;COSMIC	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q14004	CDK13	O14757	CHEK1	S433	I438S	438	Missense	distal	5	no	11.421	11.564	EPSD	TCGA;ICGC	5.604	Up-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q14004	CDK13	O14757	CHEK1	S433	R434C	434	Missense	proximal	1	no	11.421	11.411	EPSD	TCGA;ICGC;COSMIC	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q14004	CDK13	O14757	CHEK1	S437	P440S	440	Missense	distal	3	no	10.637	10.307	PhosphoSitePlus	TCGA;ICGC;COSMIC	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q14004	CDK13	O14757	CHEK1	S437	I438S	438	Missense	proximal	1	no	10.637	10.672	PhosphoSitePlus	TCGA;ICGC	5.604	Up-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q14004	CDK13	O14757	CHEK1	S437	R434C	434	Missense	distal	-3	no	10.637	2.545	PhosphoSitePlus	TCGA;ICGC;COSMIC	5.604	Loss
CAMK_CAMKL_CHK1_CHEK1_ST	Q14004	CDK13	O14757	CHEK1	S630	R626Q	626	Missense	distal	-4	no	5.529	5.689	EPSD	TCGA;ICGC;COSMIC;GDSC;CCLE	5.604	Gain
CAMK_CAMKL_CHK1_CHEK1_ST	Q14004	CDK13	O14757	CHEK1	S630	D623A	623	Missense	distal	-7	no	5.529	6.209	EPSD	TCGA;ICGC;COSMIC	5.604	Gain
CAMK_CAMKL_CHK1_CHEK1_ST	Q14004	CDK13	O14757	CHEK1	S630	K636N	636	Missense	distal	6	no	5.529	5.663	EPSD	TCGA;ICGC	5.604	Gain
CAMK_CAMKL_CHK1_CHEK1_ST	Q14004	CDK13	O14757	CHEK1	S863	Y870N	870	Missense	distal	7	no	12.300	13.044	EPSD	TCGA;ICGC;COSMIC	5.604	Up-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q14004	CDK13	O14757	CHEK1	S863	R860Q	860	Missense	distal	-3	no	12.300	5.093	EPSD	TCGA;ICGC;COSMIC	5.604	Loss
CAMK_CAMKL_CHK1_CHEK1_ST	Q14004	CDK13	O14757	CHEK1	S863	P869S	869	Missense	distal	6	no	12.300	11.680	EPSD	TCGA;ICGC;COSMIC	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q14004	CDK13	O14757	CHEK1	S863	R868Q	868	Missense	distal	5	no	12.300	12.375	EPSD	TCGA;ICGC;COSMIC	5.604	Up-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q14004	CDK13	O14757	CHEK1	T871	Y870N	870	Missense	proximal	-1	no	8.053	7.943	EPSD	TCGA;ICGC;COSMIC	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q14004	CDK13	O14757	CHEK1	T871	P869S	869	Missense	proximal	-2	no	8.053	7.769	EPSD	TCGA;ICGC;COSMIC	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q14004	CDK13	O14757	CHEK1	T871	R868Q	868	Missense	distal	-3	no	8.053	0.846	EPSD	TCGA;ICGC;COSMIC	5.604	Loss
CAMK_CAMKL_CHK1_CHEK1_ST	Q14004	CDK13	O14757	CHEK1	T1058	N1057T	1057	Missense	proximal	-1	no	7.433	7.419	EPSD	TCGA	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q14004	CDK13	O14757	CHEK1	T1058	T1058A	1058	Missense	central	0	yes	7.433	0.000	EPSD	TCGA;ICGC;COSMIC	5.604	Loss
CAMK_CAMKL_CHK1_CHEK1_ST	Q6T4R5	NHS	O14757	CHEK1	S140	A146T	146	Missense	distal	6	no	10.545	10.467	EPSD	TCGA;ICGC;COSMIC	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q6T4R5	NHS	O14757	CHEK1	S140	D141V	141	Missense	proximal	1	no	10.545	10.434	EPSD	TCGA;ICGC;COSMIC	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q6T4R5	NHS	O14757	CHEK1	S140	D141Y	141	Missense	proximal	1	no	10.545	10.423	EPSD	TCGA;ICGC;COSMIC	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q6T4R5	NHS	O14757	CHEK1	S566	L563M	563	Missense	distal	-3	no	-4.378	9.020	EPSD	TCGA;ICGC;COSMIC	5.604	Gain
CAMK_CAMKL_CHK1_CHEK1_ST	Q5JTH9	RRP12	O14757	CHEK1	S9	V11G	11	Missense	proximal	2	no	7.159	7.200	EPSD	TCGA;ICGC	5.604	Up-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q5JTH9	RRP12	O14757	CHEK1	S23	K19E	19	Missense	distal	-4	no	6.161	6.263	EPSD	TCGA;ICGC;COSMIC	5.604	Up-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q5JTH9	RRP12	O14757	CHEK1	S23	A29T	29	Missense	distal	6	no	6.161	6.083	EPSD	TCGA;ICGC	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q5JTH9	RRP12	O14757	CHEK1	S608	A604S	604	Missense	distal	-4	no	5.768	5.388	EPSD	TCGA;ICGC;COSMIC	5.604	Loss
CAMK_CAMKL_CHK1_CHEK1_ST	Q5JTH9	RRP12	O14757	CHEK1	S652	T646M	646	Missense	distal	-6	no	7.770	7.763	EPSD	TCGA;ICGC;COSMIC	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q5JTH9	RRP12	O14757	CHEK1	S829	R836H	836	Missense	distal	7	no	6.515	6.222	EPSD	TCGA;ICGC;COSMIC	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q5JTH9	RRP12	O14757	CHEK1	S829	D823N	823	Missense	distal	-6	no	6.515	6.728	EPSD	TCGA;ICGC	5.604	Up-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q5JTH9	RRP12	O14757	CHEK1	S1105	R1106L	1106	Missense	proximal	1	no	10.895	10.861	EPSD	TCGA	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q5JTH9	RRP12	O14757	CHEK1	S1105	Q1103R	1103	Missense	proximal	-2	no	10.895	10.849	EPSD	TCGA;ICGC;COSMIC	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q5JTH9	RRP12	O14757	CHEK1	S1105	R1106W	1106	Missense	proximal	1	no	10.895	10.866	EPSD	TCGA;ICGC;COSMIC	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q9HAW4	CLSPN	O14757	CHEK1	S253	S253F	253	Missense	central	0	yes	8.166	0.000	EPSD	TCGA;ICGC;COSMIC	5.604	Loss
CAMK_CAMKL_CHK1_CHEK1_ST	Q9HAW4	CLSPN	O14757	CHEK1	S253	G257V	257	Missense	distal	4	no	8.166	8.210	EPSD	TCGA;ICGC;COSMIC	5.604	Up-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q9HAW4	CLSPN	O14757	CHEK1	S253	E251K	251	Missense	proximal	-2	no	8.166	8.023	EPSD	TCGA;ICGC;COSMIC	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q9HAW4	CLSPN	O14757	CHEK1	S341	S336P	336	Missense	distal	-5	no	5.730	4.211	EPSD	TCGA;ICGC;COSMIC	5.604	Loss
CAMK_CAMKL_CHK1_CHEK1_ST	Q9HAW4	CLSPN	O14757	CHEK1	S798	Q792K	792	Missense	distal	-6	no	7.299	7.207	EPSD	TCGA;COSMIC	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q9HAW4	CLSPN	O14757	CHEK1	S798	F800L	800	Missense	proximal	2	no	7.299	7.050	EPSD	TCGA;ICGC;COSMIC	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q9HAW4	CLSPN	O14757	CHEK1	S798	P801H	801	Missense	distal	3	no	7.299	6.998	EPSD	TCGA;COSMIC	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q9HAW4	CLSPN	O14757	CHEK1	S798	R795L	795	Missense	distal	-3	no	7.299	-11.247	EPSD	TCGA;ICGC;COSMIC	5.604	Loss
CAMK_CAMKL_CHK1_CHEK1_ST	Q9HAW4	CLSPN	O14757	CHEK1	S798	P801S	801	Missense	distal	3	no	7.299	6.970	EPSD	TCGA;ICGC;COSMIC	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q9HAW4	CLSPN	O14757	CHEK1	S798	G796E	796	Missense	proximal	-2	no	7.299	7.228	EPSD	TCGA;COSMIC	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q9HAW4	CLSPN	O14757	CHEK1	S798	A803S	803	Missense	distal	5	no	7.299	7.281	EPSD	TCGA;COSMIC	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q9HAW4	CLSPN	O14757	CHEK1	S810	P809S	809	Missense	proximal	-1	no	7.595	7.148	EPSD	TCGA;COSMIC	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q9HAW4	CLSPN	O14757	CHEK1	S810	A803S	803	Missense	distal	-7	no	7.595	7.145	EPSD	TCGA;COSMIC	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q9HAW4	CLSPN	O14757	CHEK1	S921	Q922E	922	Missense	proximal	1	no	9.563	9.629	EPSD	TCGA;ICGC;COSMIC	5.604	Up-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q9HAW4	CLSPN	O14757	CHEK1	S1223	R1224C	1224	Missense	proximal	1	no	9.247	9.237	EPSD	TCGA	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q9HAW4	CLSPN	O14757	CHEK1	S1300	E1294K	1294	Missense	distal	-6	no	6.030	6.062	EPSD	TCGA;ICGC;COSMIC	5.604	Up-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q9HAW4	CLSPN	O14757	CHEK1	S1300	A1295T	1295	Missense	distal	-5	no	6.030	9.891	EPSD	TCGA;ICGC;COSMIC	5.604	Up-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q9HAW4	CLSPN	O14757	CHEK1	S1310	S1310C	1310	Missense	central	0	yes	8.199	0.000	EPSD	TCGA;COSMIC	5.604	Loss
CAMK_CAMKL_CHK1_CHEK1_ST	Q9HAW4	CLSPN	O14757	CHEK1	S1310	S1314Y	1314	Missense	distal	4	no	8.199	8.373	EPSD	TCGA;COSMIC	5.604	Up-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q14738	PPP2R5D	O14757	CHEK1	S88	Q87H	87	Missense	proximal	-1	no	8.975	9.085	EPSD	TCGA;COSMIC	5.604	Up-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q14738	PPP2R5D	O14757	CHEK1	S89	Q87H	87	Missense	proximal	-2	no	7.439	7.457	EPSD	TCGA;COSMIC	5.604	Up-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q14738	PPP2R5D	O14757	CHEK1	S573	V579A	579	Missense	distal	6	no	13.785	13.897	EPSD	TCGA	5.604	Up-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	P55039	DRG2	O14757	CHEK1	S72	S72C	72	Missense	central	0	yes	5.814	0.000	PhosphoSitePlus	TCGA;ICGC;COSMIC	5.604	Loss
CAMK_CAMKL_CHK1_CHEK1_ST	P55039	DRG2	O14757	CHEK1	S72	A66V	66	Missense	distal	-6	no	5.814	5.952	PhosphoSitePlus	TCGA;ICGC;COSMIC	5.604	Up-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	P55039	DRG2	O14757	CHEK1	S72	V65M	65	Missense	distal	-7	no	5.814	5.620	PhosphoSitePlus	TCGA;ICGC;COSMIC	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	O43660	PLRG1	O14757	CHEK1	S201	I200M	200	Missense	proximal	-1	no	10.695	10.789	EPSD	TCGA;ICGC;COSMIC	5.604	Up-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	O43660	PLRG1	O14757	CHEK1	S201	R198M	198	Missense	distal	-3	no	10.695	5.547	EPSD	TCGA;COSMIC;GDSC	5.604	Loss
CAMK_CAMKL_CHK1_CHEK1_ST	O43660	PLRG1	O14757	CHEK1	S201	H203R	203	Missense	proximal	2	no	10.695	10.677	EPSD	TCGA;COSMIC	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	O43660	PLRG1	O14757	CHEK1	T386	V379A	379	Missense	distal	-7	no	8.114	8.770	EPSD	TCGA;COSMIC	5.604	Up-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	O43660	PLRG1	O14757	CHEK1	T386	S391C	391	Missense	distal	5	no	8.114	7.766	EPSD	TCGA;COSMIC	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	O43660	PLRG1	O14757	CHEK1	T386	S389C	389	Missense	distal	3	no	8.114	7.164	EPSD	TCGA;COSMIC	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	P15822	HIVEP1	O14757	CHEK1	S148	E149K	149	Missense	proximal	1	no	9.483	9.409	EPSD	TCGA;ICGC;COSMIC	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	P15822	HIVEP1	O14757	CHEK1	S148	P153T	153	Missense	distal	5	no	9.483	9.343	EPSD	TCGA;ICGC;COSMIC	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	P15822	HIVEP1	O14757	CHEK1	S148	S148Y	148	Missense	central	0	yes	9.483	0.000	EPSD	TCGA;ICGC;COSMIC	5.604	Loss
CAMK_CAMKL_CHK1_CHEK1_ST	P15822	HIVEP1	O14757	CHEK1	S148	P153S	153	Missense	distal	5	no	9.483	9.565	EPSD	TCGA;ICGC;COSMIC	5.604	Up-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	P15822	HIVEP1	O14757	CHEK1	S215	P216S	216	Missense	proximal	1	no	5.977	6.014	EPSD	TCGA;ICGC;COSMIC;CCLE	5.604	Up-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	P15822	HIVEP1	O14757	CHEK1	S577	S571P	571	Missense	distal	-6	no	9.026	9.124	EPSD	TCGA;ICGC;COSMIC	5.604	Up-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	P15822	HIVEP1	O14757	CHEK1	S681	R678H	678	Missense	distal	-3	no	9.543	3.734	EPSD	TCGA;ICGC;COSMIC	5.604	Loss
CAMK_CAMKL_CHK1_CHEK1_ST	P15822	HIVEP1	O14757	CHEK1	S804	K811M	811	Missense	distal	7	no	10.048	9.864	EPSD	TCGA	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	P15822	HIVEP1	O14757	CHEK1	S804	R802I	802	Missense	proximal	-2	no	10.048	10.077	EPSD	TCGA;ICGC	5.604	Up-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	P15822	HIVEP1	O14757	CHEK1	S805	K811M	811	Missense	distal	6	no	9.547	9.948	EPSD	TCGA	5.604	Up-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	P15822	HIVEP1	O14757	CHEK1	S805	R802I	802	Missense	distal	-3	no	9.547	0.789	EPSD	TCGA;ICGC	5.604	Loss
CAMK_CAMKL_CHK1_CHEK1_ST	P15822	HIVEP1	O14757	CHEK1	S841	S848L	848	Missense	distal	7	no	6.547	6.539	EPSD	TCGA;ICGC;COSMIC	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	P15822	HIVEP1	O14757	CHEK1	S841	S848P	848	Missense	distal	7	no	6.547	6.602	EPSD	TCGA;ICGC	5.604	Up-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	P15822	HIVEP1	O14757	CHEK1	S841	S841P	841	Missense	central	0	yes	6.547	0.000	EPSD	TCGA;ICGC;COSMIC	5.604	Loss
CAMK_CAMKL_CHK1_CHEK1_ST	P15822	HIVEP1	O14757	CHEK1	S866	H859Y	859	Missense	distal	-7	no	7.550	6.210	EPSD	TCGA;ICGC;COSMIC	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	P15822	HIVEP1	O14757	CHEK1	S866	P860S	860	Missense	distal	-6	no	7.550	7.452	EPSD	TCGA;ICGC;COSMIC	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	P15822	HIVEP1	O14757	CHEK1	T1274	K1281N	1281	Missense	distal	7	no	5.923	5.984	EPSD	TCGA;ICGC;COSMIC	5.604	Up-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	P15822	HIVEP1	O14757	CHEK1	S1300	S1297R	1297	Missense	distal	-3	no	-3.427	6.269	EPSD	TCGA;ICGC	5.604	Gain
CAMK_CAMKL_CHK1_CHEK1_ST	P15822	HIVEP1	O14757	CHEK1	S1368	T1374M	1374	Missense	distal	6	no	9.521	9.611	EPSD	TCGA;ICGC;COSMIC;CCLE	5.604	Up-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	P15822	HIVEP1	O14757	CHEK1	S1368	R1365H	1365	Missense	distal	-3	no	9.521	3.711	EPSD	TCGA;ICGC;COSMIC;CCLE	5.604	Loss
CAMK_CAMKL_CHK1_CHEK1_ST	P15822	HIVEP1	O14757	CHEK1	S1368	R1361W	1361	Missense	distal	-7	no	9.521	7.975	EPSD	TCGA;ICGC;COSMIC	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	P15822	HIVEP1	O14757	CHEK1	S1377	T1374M	1374	Missense	distal	-3	no	-8.987	6.433	EPSD	TCGA;ICGC;COSMIC;CCLE	5.604	Gain
CAMK_CAMKL_CHK1_CHEK1_ST	P15822	HIVEP1	O14757	CHEK1	S1387	D1389N	1389	Missense	proximal	2	no	6.320	6.036	EPSD	TCGA;ICGC;COSMIC	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	P15822	HIVEP1	O14757	CHEK1	S1387	S1387L	1387	Missense	central	0	yes	6.320	0.000	EPSD	TCGA;ICGC;COSMIC	5.604	Loss
CAMK_CAMKL_CHK1_CHEK1_ST	P15822	HIVEP1	O14757	CHEK1	S1434	S1434F	1434	Missense	central	0	yes	11.920	0.000	EPSD	TCGA;ICGC;COSMIC	5.604	Loss
CAMK_CAMKL_CHK1_CHEK1_ST	P15822	HIVEP1	O14757	CHEK1	S1434	S1441R	1441	Missense	distal	7	no	11.920	12.013	EPSD	TCGA;ICGC	5.604	Up-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	P15822	HIVEP1	O14757	CHEK1	S1749	S1749P	1749	Missense	central	0	yes	10.716	0.000	PhosphoSitePlus	TCGA;ICGC;COSMIC	5.604	Loss
CAMK_CAMKL_CHK1_CHEK1_ST	P15822	HIVEP1	O14757	CHEK1	S1749	S1749F	1749	Missense	central	0	yes	10.716	0.000	PhosphoSitePlus	TCGA;ICGC;COSMIC	5.604	Loss
CAMK_CAMKL_CHK1_CHEK1_ST	P15822	HIVEP1	O14757	CHEK1	S1749	S1743L	1743	Missense	distal	-6	no	10.716	10.740	PhosphoSitePlus	TCGA;ICGC;CCLE	5.604	Up-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	P15822	HIVEP1	O14757	CHEK1	S1952	L1947P	1947	Missense	distal	-5	no	11.395	6.688	EPSD	TCGA;ICGC	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	P15822	HIVEP1	O14757	CHEK1	S2101	R2108Q	2108	Missense	distal	7	no	5.982	6.137	EPSD	TCGA;ICGC;COSMIC	5.604	Up-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	P15822	HIVEP1	O14757	CHEK1	S2101	R2096C	2096	Missense	distal	-5	no	5.982	5.304	EPSD	TCGA;ICGC;COSMIC	5.604	Loss
CAMK_CAMKL_CHK1_CHEK1_ST	P15822	HIVEP1	O14757	CHEK1	S2273	R2280H	2280	Missense	distal	7	no	7.067	6.774	EPSD	TCGA	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	P15822	HIVEP1	O14757	CHEK1	S2273	S2273Y	2273	Missense	central	0	yes	7.067	0.000	EPSD	TCGA;ICGC;COSMIC	5.604	Loss
CAMK_CAMKL_CHK1_CHEK1_ST	P15822	HIVEP1	O14757	CHEK1	S2599	V2594I	2594	Missense	distal	-5	no	8.799	10.244	EPSD	TCGA;ICGC;COSMIC	5.604	Up-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	P15822	HIVEP1	O14757	CHEK1	T2699	R2696M	2696	Missense	distal	-3	no	6.307	1.159	EPSD	TCGA;ICGC;COSMIC	5.604	Loss
CAMK_CAMKL_CHK1_CHEK1_ST	P15822	HIVEP1	O14757	CHEK1	T2699	L2693V	2693	Missense	distal	-6	no	6.307	6.295	EPSD	TCGA;ICGC;COSMIC	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	P15822	HIVEP1	O14757	CHEK1	T2699	D2704N	2704	Missense	distal	5	no	6.307	6.219	EPSD	TCGA;ICGC;COSMIC	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	P15822	HIVEP1	O14757	CHEK1	T2699	R2695Q	2695	Missense	distal	-4	no	6.307	6.467	EPSD	TCGA;ICGC;COSMIC	5.604	Up-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	P15822	HIVEP1	O14757	CHEK1	T2699	V2705L	2705	Missense	distal	6	no	6.307	6.441	EPSD	TCGA;ICGC;COSMIC	5.604	Up-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q9HB96	FANCE	O14757	CHEK1	S180	L178F	178	Missense	proximal	-2	no	9.078	9.263	EPSD	TCGA;ICGC;COSMIC	5.604	Up-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q9HB96	FANCE	O14757	CHEK1	S180	S180F	180	Missense	central	0	yes	9.078	0.000	EPSD	TCGA;ICGC;COSMIC	5.604	Loss
CAMK_CAMKL_CHK1_CHEK1_ST	Q9HB96	FANCE	O14757	CHEK1	S204	R200C	200	Missense	distal	-4	no	8.434	8.060	EPSD	TCGA;ICGC;COSMIC;GDSC	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q9HB96	FANCE	O14757	CHEK1	S204	R200H	200	Missense	distal	-4	no	8.434	8.236	EPSD	TCGA;ICGC;COSMIC	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q9HB96	FANCE	O14757	CHEK1	S374	R381H	381	Missense	distal	7	no	14.596	14.303	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q96QD9	FYTTD1	O14757	CHEK1	S118	G112E	112	Missense	distal	-6	no	7.159	7.000	EPSD	TCGA;COSMIC	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	P06493	CDK1	O14757	CHEK1	S39	R36K	36	Missense	distal	-3	no	12.639	8.814	EPSD	TCGA;ICGC;COSMIC	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	P06493	CDK1	O14757	CHEK1	S53	E57V	57	Missense	distal	4	no	5.802	5.954	EPSD	TCGA;ICGC;COSMIC	5.604	Up-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	P06493	CDK1	O14757	CHEK1	S53	R59C	59	Missense	distal	6	no	5.802	6.096	EPSD	TCGA;ICGC;COSMIC;GDSC	5.604	Up-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	P06493	CDK1	O14757	CHEK1	S53	R50W	50	Missense	distal	-3	no	5.802	-27.801	EPSD	TCGA;ICGC;COSMIC	5.604	Loss
CAMK_CAMKL_CHK1_CHEK1_ST	P06493	CDK1	O14757	CHEK1	T183	R180H	180	Missense	distal	-3	no	7.979	2.170	EPSD	TCGA;ICGC;COSMIC	5.604	Loss
CAMK_CAMKL_CHK1_CHEK1_ST	P06493	CDK1	O14757	CHEK1	S208	D211G	211	Missense	distal	3	no	9.309	7.665	PhosphoSitePlus	TCGA;ICGC;COSMIC	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	P06493	CDK1	O14757	CHEK1	S208	L213P	213	Missense	distal	5	no	9.309	9.471	PhosphoSitePlus	TCGA;ICGC;COSMIC	5.604	Up-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	P06493	CDK1	O14757	CHEK1	S248	S251F	251	Missense	distal	3	no	5.583	5.771	EPSD	TCGA;ICGC;COSMIC	5.604	Gain
CAMK_CAMKL_CHK1_CHEK1_ST	P06493	CDK1	O14757	CHEK1	S248	V253A	253	Missense	distal	5	no	5.583	5.686	EPSD	TCGA;ICGC	5.604	Gain
CAMK_CAMKL_CHK1_CHEK1_ST	Q9BY77	POLDIP3	O14757	CHEK1	T256	L250F	250	Missense	distal	-6	no	7.393	7.642	EPSD	TCGA;ICGC;COSMIC	5.604	Up-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q9BY77	POLDIP3	O14757	CHEK1	T256	R255Q	255	Missense	proximal	-1	no	7.393	7.408	EPSD	TCGA;ICGC;COSMIC	5.604	Up-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q9BY77	POLDIP3	O14757	CHEK1	S375	R379C	379	Missense	distal	4	no	6.093	6.197	EPSD	TCGA;ICGC;COSMIC	5.604	Up-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q9BY77	POLDIP3	O14757	CHEK1	S375	P369Q	369	Missense	distal	-6	no	6.093	5.998	EPSD	TCGA;ICGC;COSMIC	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q9BY77	POLDIP3	O14757	CHEK1	S375	R380K	380	Missense	distal	5	no	6.093	6.217	EPSD	TCGA;ICGC;COSMIC	5.604	Up-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q9BY77	POLDIP3	O14757	CHEK1	S383	R379C	379	Missense	distal	-4	no	9.236	8.862	EPSD	TCGA;ICGC;COSMIC	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q9BY77	POLDIP3	O14757	CHEK1	S383	R380K	380	Missense	distal	-3	no	9.236	5.410	EPSD	TCGA;ICGC;COSMIC	5.604	Loss
CAMK_CAMKL_CHK1_CHEK1_ST	P26373	RPL13	O14757	CHEK1	S106	P100T	100	Missense	distal	-6	no	8.211	8.183	EPSD	TCGA;ICGC;COSMIC	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	P26373	RPL13	O14757	CHEK1	S106	R101K	101	Missense	distal	-5	no	8.211	9.387	EPSD	TCGA;ICGC;COSMIC	5.604	Up-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	P26373	RPL13	O14757	CHEK1	S106	S109F	109	Missense	distal	3	no	8.211	8.400	EPSD	TCGA;ICGC;COSMIC	5.604	Up-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	P26373	RPL13	O14757	CHEK1	S132	S132L	132	Missense	central	0	yes	7.319	0.000	EPSD	TCGA;ICGC;COSMIC	5.604	Loss
CAMK_CAMKL_CHK1_CHEK1_ST	P26373	RPL13	O14757	CHEK1	S139	S132L	132	Missense	distal	-7	no	6.106	5.222	EPSD	TCGA;ICGC;COSMIC	5.604	Loss
CAMK_CAMKL_CHK1_CHEK1_ST	P26373	RPL13	O14757	CHEK1	S139	S140F	140	Missense	proximal	1	no	6.106	6.102	EPSD	TCGA;ICGC;COSMIC	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	P26373	RPL13	O14757	CHEK1	S139	E143K	143	Missense	distal	4	no	6.106	6.100	EPSD	TCGA;ICGC;COSMIC	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	P26373	RPL13	O14757	CHEK1	S140	S140F	140	Missense	central	0	yes	6.494	0.000	EPSD	TCGA;ICGC;COSMIC	5.604	Loss
CAMK_CAMKL_CHK1_CHEK1_ST	P26373	RPL13	O14757	CHEK1	S140	E143K	143	Missense	distal	3	no	6.494	5.678	EPSD	TCGA;ICGC;COSMIC	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	P18858	LIG1	O14757	CHEK1	T311	T311M	311	Missense	central	0	yes	7.858	0.000	EPSD	TCGA;COSMIC	5.604	Loss
CAMK_CAMKL_CHK1_CHEK1_ST	P18858	LIG1	O14757	CHEK1	T311	R317C	317	Missense	distal	6	no	7.858	8.152	EPSD	TCGA;COSMIC	5.604	Up-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	P18858	LIG1	O14757	CHEK1	T311	R307G	307	Missense	distal	-4	no	7.858	7.885	EPSD	TCGA;COSMIC	5.604	Up-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	P18858	LIG1	O14757	CHEK1	T311	S318F	318	Missense	distal	7	no	7.858	7.428	EPSD	TCGA;COSMIC	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	P18858	LIG1	O14757	CHEK1	T311	R307Q	307	Missense	distal	-4	no	7.858	8.018	EPSD	TCGA;COSMIC	5.604	Up-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	P18858	LIG1	O14757	CHEK1	S419	R413W	413	Missense	distal	-6	no	7.217	7.537	EPSD	TCGA;COSMIC	5.604	Up-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	P18858	LIG1	O14757	CHEK1	S419	T420I	420	Missense	proximal	1	no	7.217	7.174	EPSD	TCGA;COSMIC	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	P18858	LIG1	O14757	CHEK1	S419	A421S	421	Missense	proximal	2	no	7.217	6.761	EPSD	TCGA;COSMIC	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	P18858	LIG1	O14757	CHEK1	S552	R557C	557	Missense	distal	5	no	7.927	7.683	EPSD	TCGA;COSMIC	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	P18858	LIG1	O14757	CHEK1	S552	R557H	557	Missense	distal	5	no	7.927	7.943	EPSD	TCGA;COSMIC	5.604	Up-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	P18858	LIG1	O14757	CHEK1	S901	R898Q	898	Missense	distal	-3	no	14.400	7.193	EPSD	TCGA;COSMIC	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	P18858	LIG1	O14757	CHEK1	S901	N905S	905	Missense	distal	4	no	14.400	14.380	EPSD	TCGA;COSMIC	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	P43405	SYK	O14757	CHEK1	S93	Y91C	91	Missense	proximal	-2	no	7.128	7.063	EPSD	TCGA;ICGC;COSMIC	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	P43405	SYK	O14757	CHEK1	S93	A86T	86	Missense	distal	-7	no	7.128	5.811	EPSD	TCGA;ICGC;GDSC;CCLE	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	P43405	SYK	O14757	CHEK1	S295	G288R	288	Missense	distal	-7	no	11.476	11.438	PhosphoSitePlus	TCGA;ICGC;COSMIC	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	P43405	SYK	O14757	CHEK1	S295	I289M	289	Missense	distal	-6	no	11.476	11.540	PhosphoSitePlus	TCGA;ICGC;COSMIC	5.604	Up-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	P43405	SYK	O14757	CHEK1	S295	S297C	297	Missense	proximal	2	no	11.476	11.115	PhosphoSitePlus	TCGA;ICGC;COSMIC	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	P43405	SYK	O14757	CHEK1	S295	G288E	288	Missense	distal	-7	no	11.476	11.921	PhosphoSitePlus	TCGA;ICGC;COSMIC	5.604	Up-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	P43405	SYK	O14757	CHEK1	S295	R292I	292	Missense	distal	-3	no	11.476	2.718	PhosphoSitePlus	TCGA;ICGC	5.604	Loss
CAMK_CAMKL_CHK1_CHEK1_ST	P43405	SYK	O14757	CHEK1	S297	S297C	297	Missense	central	0	yes	5.822	0.000	EPSD	TCGA;ICGC;COSMIC	5.604	Loss
CAMK_CAMKL_CHK1_CHEK1_ST	P43405	SYK	O14757	CHEK1	S297	R292I	292	Missense	distal	-5	no	5.822	6.767	EPSD	TCGA;ICGC	5.604	Up-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	P43405	SYK	O14757	CHEK1	S307	G311R	311	Missense	distal	4	no	12.325	12.308	EPSD	TCGA;COSMIC	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	P43405	SYK	O14757	CHEK1	S316	G311R	311	Missense	distal	-5	no	8.686	8.851	EPSD	TCGA;COSMIC	5.604	Up-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	P43405	SYK	O14757	CHEK1	S316	S316G	316	Missense	central	0	yes	8.686	0.000	EPSD	TCGA;COSMIC	5.604	Loss
CAMK_CAMKL_CHK1_CHEK1_ST	P43405	SYK	O14757	CHEK1	S316	F320L	320	Missense	distal	4	no	8.686	8.624	EPSD	TCGA;COSMIC	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	P43405	SYK	O14757	CHEK1	S579	E580D	580	Missense	proximal	1	no	5.736	5.740	EPSD	TCGA;COSMIC	5.604	Up-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	P43405	SYK	O14757	CHEK1	S579	G575E	575	Missense	distal	-4	no	5.736	5.913	EPSD	TCGA;COSMIC	5.604	Up-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	P43405	SYK	O14757	CHEK1	S579	G578E	578	Missense	proximal	-1	no	5.736	5.628	EPSD	TCGA;COSMIC;GDSC;CCLE	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	P43405	SYK	O14757	CHEK1	S579	E580K	580	Missense	proximal	1	no	5.736	5.662	EPSD	TCGA;COSMIC	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	P43405	SYK	O14757	CHEK1	S579	E586D	586	Missense	distal	7	no	5.736	5.794	EPSD	TCGA;GDSC;CCLE	5.604	Up-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	P43405	SYK	O14757	CHEK1	S579	R574Q	574	Missense	distal	-5	no	5.736	5.340	EPSD	TCGA;COSMIC	5.604	Loss
CAMK_CAMKL_CHK1_CHEK1_ST	P52294	KPNA1	O14757	CHEK1	S13	R10C	10	Missense	distal	-3	no	10.253	2.162	EPSD	TCGA;ICGC;COSMIC	5.604	Loss
CAMK_CAMKL_CHK1_CHEK1_ST	P52294	KPNA1	O14757	CHEK1	S13	E7D	7	Missense	distal	-6	no	10.253	10.203	EPSD	TCGA;ICGC;COSMIC	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	P52294	KPNA1	O14757	CHEK1	S221	R225C	225	Missense	distal	4	no	7.413	7.516	EPSD	TCGA;ICGC;COSMIC	5.604	Up-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	P52294	KPNA1	O14757	CHEK1	S244	E248K	248	Missense	distal	4	no	13.709	13.703	EPSD	TCGA;ICGC;COSMIC	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	P52294	KPNA1	O14757	CHEK1	T396	R395W	395	Missense	proximal	-1	no	5.697	5.815	EPSD	TCGA;ICGC;COSMIC	5.604	Up-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	P52294	KPNA1	O14757	CHEK1	T396	A392S	392	Missense	distal	-4	no	5.697	5.318	EPSD	TCGA	5.604	Loss
CAMK_CAMKL_CHK1_CHEK1_ST	P52294	KPNA1	O14757	CHEK1	T396	R397K	397	Missense	proximal	1	no	5.697	5.698	EPSD	TCGA;ICGC;COSMIC	5.604	Up-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	P52294	KPNA1	O14757	CHEK1	T396	R395Q	395	Missense	proximal	-1	no	5.697	5.713	EPSD	TCGA;ICGC;COSMIC	5.604	Up-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q8N4C8	MINK1	O14757	CHEK1	T59	E63K	63	Missense	distal	4	no	5.783	5.777	EPSD	TCGA;ICGC;COSMIC	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q8N4C8	MINK1	O14757	CHEK1	T187	I189N	189	Missense	proximal	2	no	8.698	9.386	EPSD	TCGA;ICGC;COSMIC	5.604	Up-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q8N4C8	MINK1	O14757	CHEK1	T187	R184K	184	Missense	distal	-3	no	8.698	4.872	EPSD	TCGA	5.604	Loss
CAMK_CAMKL_CHK1_CHEK1_ST	Q8N4C8	MINK1	O14757	CHEK1	T280	T280M	280	Missense	central	0	yes	11.652	0.000	PhosphoSitePlus	TCGA;ICGC;COSMIC	5.604	Loss
CAMK_CAMKL_CHK1_CHEK1_ST	Q8N4C8	MINK1	O14757	CHEK1	S601	D604N	604	Missense	distal	3	no	11.420	10.704	EPSD	TCGA;ICGC;COSMIC	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q8N4C8	MINK1	O14757	CHEK1	S601	R598Q	598	Missense	distal	-3	no	11.420	4.213	EPSD	TCGA;ICGC;COSMIC	5.604	Loss
CAMK_CAMKL_CHK1_CHEK1_ST	Q8N4C8	MINK1	O14757	CHEK1	S641	D642H	642	Missense	proximal	1	no	9.572	9.428	EPSD	TCGA;ICGC;COSMIC	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q8N4C8	MINK1	O14757	CHEK1	S641	R638H	638	Missense	distal	-3	no	9.572	3.763	EPSD	TCGA;ICGC	5.604	Loss
CAMK_CAMKL_CHK1_CHEK1_ST	Q8N4C8	MINK1	O14757	CHEK1	S699	R694C	694	Missense	distal	-5	no	9.766	9.087	EPSD	TCGA;ICGC;COSMIC	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q8N4C8	MINK1	O14757	CHEK1	S699	A702T	702	Missense	distal	3	no	9.766	9.528	EPSD	TCGA;ICGC	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q8N4C8	MINK1	O14757	CHEK1	S701	R694C	694	Missense	distal	-7	no	9.668	8.940	EPSD	TCGA;ICGC;COSMIC	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q8N4C8	MINK1	O14757	CHEK1	S701	A702T	702	Missense	proximal	1	no	9.668	9.658	EPSD	TCGA;ICGC	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q8N4C8	MINK1	O14757	CHEK1	S749	S754C	754	Missense	distal	5	no	8.314	7.967	EPSD	TCGA;ICGC;COSMIC	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q8N4C8	MINK1	O14757	CHEK1	S749	G756R	756	Missense	distal	7	no	8.314	8.308	EPSD	TCGA;ICGC;COSMIC	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q8N4C8	MINK1	O14757	CHEK1	S772	V769M	769	Missense	distal	-3	no	3.617	6.932	EPSD	TCGA;ICGC;COSMIC	5.604	Gain
CAMK_CAMKL_CHK1_CHEK1_ST	Q8N4C8	MINK1	O14757	CHEK1	S993	V995F	995	Missense	proximal	2	no	10.038	10.000	EPSD	TCGA;ICGC;COSMIC	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q8N4C8	MINK1	O14757	CHEK1	S1006	R1003Q	1003	Missense	distal	-3	no	11.868	4.661	EPSD	TCGA	5.604	Loss
CAMK_CAMKL_CHK1_CHEK1_ST	Q8N4C8	MINK1	O14757	CHEK1	S1006	R1012W	1012	Missense	distal	6	no	11.868	12.334	EPSD	TCGA;ICGC;COSMIC	5.604	Up-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	P30307	CDC25C	O14757	CHEK1	S38	D36Y	36	Missense	proximal	-2	no	10.974	11.039	EPSD	TCGA;ICGC	5.604	Up-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	P30307	CDC25C	O14757	CHEK1	S216	N222K	222	Missense	distal	6	no	12.705	12.570	PhosphoSitePlus	TCGA;ICGC;COSMIC	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	P30307	CDC25C	O14757	CHEK1	S216	P215Q	215	Missense	proximal	-1	no	12.705	12.435	PhosphoSitePlus	TCGA;ICGC;COSMIC	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	P30307	CDC25C	O14757	CHEK1	S216	R213H	213	Missense	distal	-3	no	12.705	6.896	PhosphoSitePlus	TCGA;ICGC;COSMIC	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	P30307	CDC25C	O14757	CHEK1	S216	R213C	213	Missense	distal	-3	no	12.705	4.614	PhosphoSitePlus	TCGA;ICGC;COSMIC	5.604	Loss
CAMK_CAMKL_CHK1_CHEK1_ST	P30307	CDC25C	O14757	CHEK1	S216	S214F	214	Missense	proximal	-2	no	12.705	12.995	PhosphoSitePlus	TCGA;ICGC;COSMIC	5.604	Up-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	P30307	CDC25C	O14757	CHEK1	S216	L221S	221	Missense	distal	5	no	12.705	12.949	PhosphoSitePlus	TCGA;ICGC;COSMIC	5.604	Up-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	P30307	CDC25C	O14757	CHEK1	S216	P218S	218	Missense	proximal	2	no	12.705	12.782	PhosphoSitePlus	TCGA;ICGC	5.604	Up-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	P30307	CDC25C	O14757	CHEK1	S263	S263F	263	Missense	central	0	yes	10.181	0.000	EPSD	TCGA;ICGC;COSMIC	5.604	Loss
CAMK_CAMKL_CHK1_CHEK1_ST	Q02750	MAP2K1	O14757	CHEK1	T55	R49H	49	Missense	distal	-6	no	7.717	7.827	PhosphoSitePlus	TCGA;ICGC;COSMIC	5.604	Up-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q02750	MAP2K1	O14757	CHEK1	T55	Q56P	56	Missense	proximal	1	no	7.717	7.646	PhosphoSitePlus	TCGA;ICGC;COSMIC;GDSC;CCLE	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q02750	MAP2K1	O14757	CHEK1	T55	K57N	57	Missense	proximal	2	no	7.717	7.308	PhosphoSitePlus	TCGA;ICGC;COSMIC;CCLE	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q02750	MAP2K1	O14757	CHEK1	T55	K57T	57	Missense	proximal	2	no	7.717	6.734	PhosphoSitePlus	TCGA;ICGC;COSMIC	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q02750	MAP2K1	O14757	CHEK1	T55	F53L	53	Missense	proximal	-2	no	7.717	7.532	PhosphoSitePlus	TCGA;ICGC;COSMIC;GDSC;CCLE	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q02750	MAP2K1	O14757	CHEK1	T55	F53V	53	Missense	proximal	-2	no	7.717	7.619	PhosphoSitePlus	TCGA;ICGC;COSMIC	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q02750	MAP2K1	O14757	CHEK1	T55	F53I	53	Missense	proximal	-2	no	7.717	7.555	PhosphoSitePlus	TCGA;ICGC;COSMIC	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q02750	MAP2K1	O14757	CHEK1	T292	G294R	294	Missense	proximal	2	no	5.758	5.728	EPSD	TCGA;ICGC;COSMIC	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q02750	MAP2K1	O14757	CHEK1	T292	G294V	294	Missense	proximal	2	no	5.758	5.717	EPSD	TCGA;ICGC;COSMIC	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q02750	MAP2K1	O14757	CHEK1	T292	G294E	294	Missense	proximal	2	no	5.758	6.372	EPSD	TCGA;ICGC;COSMIC	5.604	Up-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q02750	MAP2K1	O14757	CHEK1	T292	P290S	290	Missense	proximal	-2	no	5.758	5.474	EPSD	TCGA;ICGC	5.604	Loss
CAMK_CAMKL_CHK1_CHEK1_ST	Q02750	MAP2K1	O14757	CHEK1	S298	G294R	294	Missense	distal	-4	no	7.076	7.050	EPSD	TCGA;ICGC;COSMIC	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q02750	MAP2K1	O14757	CHEK1	S298	G294V	294	Missense	distal	-4	no	7.076	7.042	EPSD	TCGA;ICGC;COSMIC	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q02750	MAP2K1	O14757	CHEK1	S298	G294E	294	Missense	distal	-4	no	7.076	7.253	EPSD	TCGA;ICGC;COSMIC	5.604	Up-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q02750	MAP2K1	O14757	CHEK1	S298	R305Q	305	Missense	distal	7	no	7.076	7.231	EPSD	TCGA;ICGC	5.604	Up-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q02750	MAP2K1	O14757	CHEK1	S298	D303N	303	Missense	distal	5	no	7.076	6.987	EPSD	TCGA;ICGC;COSMIC	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	P06400	RB1	O14757	CHEK1	S83	L88F	88	Missense	distal	5	no	6.116	6.034	EPSD	TCGA;ICGC;COSMIC	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	P06400	RB1	O14757	CHEK1	S83	E79D	79	Missense	distal	-4	no	6.116	5.975	EPSD	TCGA;ICGC	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	P06400	RB1	O14757	CHEK1	S83	G90S	90	Missense	distal	7	no	6.116	6.017	EPSD	TCGA;ICGC;COSMIC	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	P06400	RB1	O14757	CHEK1	S83	V87A	87	Missense	distal	4	no	6.116	6.198	EPSD	TCGA;ICGC;COSMIC	5.604	Up-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	P06400	RB1	O14757	CHEK1	S163	E170A	170	Missense	distal	7	no	7.685	7.401	EPSD	TCGA;ICGC	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	P06400	RB1	O14757	CHEK1	S163	E170G	170	Missense	distal	7	no	7.685	7.450	EPSD	TCGA;ICGC;COSMIC	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	P06400	RB1	O14757	CHEK1	S163	V157A	157	Missense	distal	-6	no	7.685	7.547	EPSD	TCGA;ICGC;COSMIC	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	P06400	RB1	O14757	CHEK1	T619	S624Y	624	Missense	distal	5	no	7.081	6.627	EPSD	TCGA;ICGC;COSMIC	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	P06400	RB1	O14757	CHEK1	T619	R621H	621	Missense	proximal	2	no	7.081	7.100	EPSD	TCGA;ICGC;COSMIC;CCLE	5.604	Up-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	P06400	RB1	O14757	CHEK1	S624	Q631H	631	Missense	distal	7	no	11.640	11.192	EPSD	TCGA;ICGC;COSMIC	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	P06400	RB1	O14757	CHEK1	S624	S624Y	624	Missense	central	0	yes	11.640	0.000	EPSD	TCGA;ICGC;COSMIC	5.604	Loss
CAMK_CAMKL_CHK1_CHEK1_ST	P06400	RB1	O14757	CHEK1	S624	R621H	621	Missense	distal	-3	no	11.640	5.831	EPSD	TCGA;ICGC;COSMIC;CCLE	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	P06400	RB1	O14757	CHEK1	T766	M761L	761	Missense	distal	-5	no	5.906	10.279	EPSD	TCGA;ICGC;COSMIC	5.604	Up-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	P06400	RB1	O14757	CHEK1	T778	I782M	782	Missense	distal	4	no	7.192	7.251	EPSD	TCGA;ICGC;COSMIC	5.604	Up-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	P19838	NFKB1	O14757	CHEK1	S328	R335Q	335	Missense	distal	7	no	8.043	8.198	PhosphoSitePlus	TCGA;COSMIC	5.604	Up-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	P19838	NFKB1	O14757	CHEK1	S337	R335Q	335	Missense	proximal	-2	no	7.660	7.706	EPSD	TCGA;COSMIC	5.604	Up-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q9BXB4	OSBPL11	O14757	CHEK1	S43	S40R	40	Missense	distal	-3	no	-1.567	8.129	EPSD	TCGA;ICGC;COSMIC	5.604	Gain
CAMK_CAMKL_CHK1_CHEK1_ST	Q9BXB4	OSBPL11	O14757	CHEK1	S48	S43T	43	Missense	distal	-5	no	10.060	11.192	EPSD	TCGA;ICGC;COSMIC	5.604	Up-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q9BXB4	OSBPL11	O14757	CHEK1	S48	S43C	43	Missense	distal	-5	no	10.060	9.593	EPSD	TCGA;ICGC;COSMIC	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q9BXB4	OSBPL11	O14757	CHEK1	S170	P167S	167	Missense	distal	-3	no	5.967	3.407	EPSD	TCGA;ICGC;COSMIC	5.604	Loss
CAMK_CAMKL_CHK1_CHEK1_ST	Q9BXB4	OSBPL11	O14757	CHEK1	S174	S181A	181	Missense	distal	7	no	11.064	11.113	EPSD	TCGA;ICGC;COSMIC	5.604	Up-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q9BXB4	OSBPL11	O14757	CHEK1	S174	P167S	167	Missense	distal	-7	no	11.064	11.734	EPSD	TCGA;ICGC;COSMIC	5.604	Up-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q96RL1	UIMC1	O14757	CHEK1	S12	S14F	14	Missense	proximal	2	no	7.956	7.811	EPSD	TCGA;ICGC;COSMIC	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q96RL1	UIMC1	O14757	CHEK1	S12	E13K	13	Missense	proximal	1	no	7.956	7.882	EPSD	TCGA;ICGC	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q96RL1	UIMC1	O14757	CHEK1	S330	P326R	326	Missense	distal	-4	no	11.430	11.501	EPSD	TCGA;ICGC;COSMIC	5.604	Up-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q96RL1	UIMC1	O14757	CHEK1	S330	P329L	329	Missense	proximal	-1	no	11.430	11.243	EPSD	TCGA;ICGC;COSMIC	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q96RL1	UIMC1	O14757	CHEK1	S330	P329S	329	Missense	proximal	-1	no	11.430	10.983	EPSD	TCGA;ICGC;COSMIC	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q96RL1	UIMC1	O14757	CHEK1	S463	P464L	464	Missense	proximal	1	no	10.592	10.620	EPSD	TCGA;ICGC;COSMIC	5.604	Up-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q96RL1	UIMC1	O14757	CHEK1	S627	R624Q	624	Missense	distal	-3	no	7.791	0.584	PhosphoSitePlus	TCGA;COSMIC	5.604	Loss
CAMK_CAMKL_CHK1_CHEK1_ST	Q96RL1	UIMC1	O14757	CHEK1	S627	R624L	624	Missense	distal	-3	no	7.791	-10.755	PhosphoSitePlus	TCGA;COSMIC	5.604	Loss
CAMK_CAMKL_CHK1_CHEK1_ST	Q96RL1	UIMC1	O14757	CHEK1	S653	A648S	648	Missense	distal	-5	no	4.192	6.920	EPSD	TCGA;COSMIC	5.604	Gain
CAMK_CAMKL_CHK1_CHEK1_ST	Q96ST3	SIN3A	O14757	CHEK1	S139	Y144D	144	Missense	distal	5	no	5.638	6.179	EPSD	TCGA;ICGC;COSMIC	5.604	Up-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q96ST3	SIN3A	O14757	CHEK1	S139	Q140K	140	Missense	proximal	1	no	5.638	5.630	EPSD	TCGA;ICGC;COSMIC	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q96ST3	SIN3A	O14757	CHEK1	T432	R428C	428	Missense	distal	-4	no	9.233	8.859	EPSD	TCGA;ICGC;COSMIC	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q96ST3	SIN3A	O14757	CHEK1	T432	T432I	432	Missense	central	0	yes	9.233	0.000	EPSD	TCGA;ICGC;COSMIC	5.604	Loss
CAMK_CAMKL_CHK1_CHEK1_ST	Q96ST3	SIN3A	O14757	CHEK1	T432	C425F	425	Missense	distal	-7	no	9.233	8.488	EPSD	TCGA;ICGC;COSMIC	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q96ST3	SIN3A	O14757	CHEK1	S641	E646K	646	Missense	distal	5	no	6.078	6.013	EPSD	TCGA;ICGC;COSMIC	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q96ST3	SIN3A	O14757	CHEK1	S641	L640F	640	Missense	proximal	-1	no	6.078	6.091	EPSD	TCGA;ICGC;COSMIC	5.604	Up-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q96ST3	SIN3A	O14757	CHEK1	S748	E752V	752	Missense	distal	4	no	8.244	8.397	EPSD	TCGA;COSMIC	5.604	Up-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q96ST3	SIN3A	O14757	CHEK1	S748	I753T	753	Missense	distal	5	no	8.244	8.165	EPSD	TCGA;ICGC;COSMIC	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q96ST3	SIN3A	O14757	CHEK1	S748	S746Y	746	Missense	proximal	-2	no	8.244	8.357	EPSD	TCGA;ICGC;COSMIC	5.604	Up-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q96ST3	SIN3A	O14757	CHEK1	S755	E752V	752	Missense	distal	-3	no	5.642	4.267	EPSD	TCGA;COSMIC	5.604	Loss
CAMK_CAMKL_CHK1_CHEK1_ST	Q96ST3	SIN3A	O14757	CHEK1	S755	I753T	753	Missense	proximal	-2	no	5.642	5.768	EPSD	TCGA;ICGC;COSMIC	5.604	Up-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q96ST3	SIN3A	O14757	CHEK1	S911	R908W	908	Missense	distal	-3	no	13.347	-20.256	EPSD	TCGA;ICGC;COSMIC	5.604	Loss
CAMK_CAMKL_CHK1_CHEK1_ST	Q96ST3	SIN3A	O14757	CHEK1	S911	E914K	914	Missense	distal	3	no	13.347	12.531	EPSD	TCGA;ICGC	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q96ST3	SIN3A	O14757	CHEK1	S938	I933V	933	Missense	distal	-5	no	8.201	6.756	EPSD	TCGA;ICGC;COSMIC	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q96ST3	SIN3A	O14757	CHEK1	S938	Q944E	944	Missense	distal	6	no	8.201	7.850	EPSD	TCGA;ICGC;COSMIC	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q96ST3	SIN3A	O14757	CHEK1	S938	S940I	940	Missense	proximal	2	no	8.201	7.695	EPSD	TCGA;ICGC	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q96ST3	SIN3A	O14757	CHEK1	S940	I933V	933	Missense	distal	-7	no	5.172	5.608	EPSD	TCGA;ICGC;COSMIC	5.604	Gain
CAMK_CAMKL_CHK1_CHEK1_ST	Q13470	TNK1	O14757	CHEK1	S68	R67H	67	Missense	proximal	-1	no	10.801	10.926	EPSD	TCGA;ICGC;COSMIC	5.604	Up-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q13470	TNK1	O14757	CHEK1	S508	G515W	515	Missense	distal	7	no	5.696	5.189	EPSD	TCGA;COSMIC	5.604	Loss
CAMK_CAMKL_CHK1_CHEK1_ST	Q32P44	EML3	O14757	CHEK1	S156	R153Q	153	Missense	distal	-3	no	9.006	1.799	EPSD	TCGA;COSMIC	5.604	Loss
CAMK_CAMKL_CHK1_CHEK1_ST	Q32P44	EML3	O14757	CHEK1	S156	S158F	158	Missense	proximal	2	no	9.006	8.862	EPSD	TCGA;COSMIC	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q32P44	EML3	O14757	CHEK1	S156	R154I	154	Missense	proximal	-2	no	9.006	9.035	EPSD	TCGA	5.604	Up-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q32P44	EML3	O14757	CHEK1	S157	R153Q	153	Missense	distal	-4	no	7.989	8.149	EPSD	TCGA;COSMIC	5.604	Up-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q32P44	EML3	O14757	CHEK1	S157	S158F	158	Missense	proximal	1	no	7.989	7.984	EPSD	TCGA;COSMIC	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q32P44	EML3	O14757	CHEK1	S157	R154I	154	Missense	distal	-3	no	7.989	-0.769	EPSD	TCGA	5.604	Loss
CAMK_CAMKL_CHK1_CHEK1_ST	Q32P44	EML3	O14757	CHEK1	S176	R183Q	183	Missense	distal	7	no	8.278	8.433	PhosphoSitePlus	TCGA;COSMIC	5.604	Up-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q32P44	EML3	O14757	CHEK1	S176	A178T	178	Missense	proximal	2	no	8.278	7.430	PhosphoSitePlus	TCGA;COSMIC	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q32P44	EML3	O14757	CHEK1	S186	E188D	188	Missense	proximal	2	no	10.618	10.535	EPSD	TCGA;COSMIC	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q32P44	EML3	O14757	CHEK1	S186	E188K	188	Missense	proximal	2	no	10.618	10.660	EPSD	TCGA;COSMIC	5.604	Up-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q32P44	EML3	O14757	CHEK1	S186	R183Q	183	Missense	distal	-3	no	10.618	3.411	EPSD	TCGA;COSMIC	5.604	Loss
CAMK_CAMKL_CHK1_CHEK1_ST	Q32P44	EML3	O14757	CHEK1	S198	G200V	200	Missense	proximal	2	no	5.937	5.895	EPSD	TCGA;COSMIC	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q32P44	EML3	O14757	CHEK1	S198	P202S	202	Missense	distal	4	no	5.937	5.797	EPSD	TCGA;ICGC;COSMIC	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q32P44	EML3	O14757	CHEK1	S198	R205L	205	Missense	distal	7	no	5.937	5.836	EPSD	TCGA;COSMIC	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q32P44	EML3	O14757	CHEK1	S490	R487W	487	Missense	distal	-3	no	9.058	-24.546	EPSD	TCGA;COSMIC;GDSC;CCLE	5.604	Loss
CAMK_CAMKL_CHK1_CHEK1_ST	Q32P44	EML3	O14757	CHEK1	S490	G496C	496	Missense	distal	6	no	9.058	9.227	EPSD	TCGA	5.604	Up-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q32P44	EML3	O14757	CHEK1	S844	S844N	844	Missense	central	0	yes	5.660	0.000	EPSD	TCGA;COSMIC	5.604	Loss
CAMK_CAMKL_CHK1_CHEK1_ST	Q32P44	EML3	O14757	CHEK1	S844	T848M	848	Missense	distal	4	no	5.660	5.759	EPSD	TCGA;COSMIC	5.604	Up-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q9Y4F5	CEP170B	O14757	CHEK1	S421	R418C	418	Missense	distal	-3	no	8.973	0.882	EPSD	TCGA	5.604	Loss
CAMK_CAMKL_CHK1_CHEK1_ST	Q9Y4F5	CEP170B	O14757	CHEK1	S421	P426L	426	Missense	distal	5	no	8.973	8.811	EPSD	TCGA;COSMIC	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q9Y4F5	CEP170B	O14757	CHEK1	S421	R415Q	415	Missense	distal	-6	no	8.973	9.055	EPSD	TCGA;COSMIC	5.604	Up-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q9Y4F5	CEP170B	O14757	CHEK1	S605	A606T	606	Missense	proximal	1	no	12.206	12.195	EPSD	TCGA;COSMIC	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q9Y4F5	CEP170B	O14757	CHEK1	S636	P638S	638	Missense	proximal	2	no	6.435	6.512	EPSD	TCGA;ICGC;COSMIC	5.604	Up-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q9Y4F5	CEP170B	O14757	CHEK1	S636	L630P	630	Missense	distal	-6	no	6.435	6.509	EPSD	TCGA;COSMIC	5.604	Up-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q9Y4F5	CEP170B	O14757	CHEK1	S636	L639R	639	Missense	distal	3	no	6.435	6.867	EPSD	TCGA;COSMIC	5.604	Up-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q9Y4F5	CEP170B	O14757	CHEK1	S711	S717N	717	Missense	distal	6	no	7.834	7.968	EPSD	TCGA	5.604	Up-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q9Y4F5	CEP170B	O14757	CHEK1	S868	E867D	867	Missense	proximal	-1	no	8.373	8.431	EPSD	TCGA;COSMIC	5.604	Up-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q9Y4F5	CEP170B	O14757	CHEK1	S868	R865W	865	Missense	distal	-3	no	8.373	-25.230	EPSD	TCGA;ICGC;COSMIC;GDSC;CCLE	5.604	Loss
CAMK_CAMKL_CHK1_CHEK1_ST	Q9Y4F5	CEP170B	O14757	CHEK1	S875	G881S	881	Missense	distal	6	no	6.636	6.424	EPSD	TCGA;COSMIC	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q9Y4F5	CEP170B	O14757	CHEK1	S875	P877L	877	Missense	proximal	2	no	6.636	6.319	EPSD	TCGA;COSMIC	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q9Y4F5	CEP170B	O14757	CHEK1	S930	E936K	936	Missense	distal	6	no	7.980	8.250	EPSD	TCGA;COSMIC	5.604	Up-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q9Y4F5	CEP170B	O14757	CHEK1	S930	D934T	934	Missense	distal	4	no	7.980	7.941	EPSD	TCGA	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q9Y4F5	CEP170B	O14757	CHEK1	S930	A926T	926	Missense	distal	-4	no	7.980	7.550	EPSD	TCGA	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q9Y4F5	CEP170B	O14757	CHEK1	T942	G939R	939	Missense	distal	-3	no	-0.163	7.611	EPSD	TCGA;COSMIC	5.604	Gain
CAMK_CAMKL_CHK1_CHEK1_ST	Q9Y4F5	CEP170B	O14757	CHEK1	S1007	H1012Q	1012	Missense	distal	5	no	8.938	8.998	EPSD	TCGA;COSMIC	5.604	Up-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q9Y4F5	CEP170B	O14757	CHEK1	S1007	S1007P	1007	Missense	central	0	yes	8.938	0.000	EPSD	TCGA;COSMIC	5.604	Loss
CAMK_CAMKL_CHK1_CHEK1_ST	Q9Y4F5	CEP170B	O14757	CHEK1	S1007	Q1006R	1006	Missense	proximal	-1	no	8.938	8.923	EPSD	TCGA	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q9Y4F5	CEP170B	O14757	CHEK1	S1057	A1062T	1062	Missense	distal	5	no	8.934	8.693	EPSD	TCGA;COSMIC	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q9Y4F5	CEP170B	O14757	CHEK1	S1165	A1161V	1161	Missense	distal	-4	no	6.049	5.970	EPSD	TCGA;ICGC	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q9Y4F5	CEP170B	O14757	CHEK1	S1165	R1166C	1166	Missense	proximal	1	no	6.049	6.039	EPSD	TCGA;COSMIC	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q9Y4F5	CEP170B	O14757	CHEK1	S1165	S1165P	1165	Missense	central	0	yes	6.049	0.000	EPSD	TCGA;COSMIC	5.604	Loss
CAMK_CAMKL_CHK1_CHEK1_ST	Q9Y4F5	CEP170B	O14757	CHEK1	S1179	R1174Q	1174	Missense	distal	-5	no	6.912	6.515	EPSD	TCGA;ICGC;COSMIC	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q9Y4F5	CEP170B	O14757	CHEK1	T1210	M1211V	1211	Missense	proximal	1	no	7.302	7.309	EPSD	TCGA	5.604	Up-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q9Y4F5	CEP170B	O14757	CHEK1	T1210	S1206N	1206	Missense	distal	-4	no	7.302	7.596	EPSD	TCGA;COSMIC	5.604	Up-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q8WWI1	LMO7	O14757	CHEK1	S706	S706P	706	Missense	central	0	yes	6.000	0.000	EPSD	TCGA;ICGC;COSMIC	5.604	Loss
CAMK_CAMKL_CHK1_CHEK1_ST	Q8WWI1	LMO7	O14757	CHEK1	T818	A824T	824	Missense	distal	6	no	9.464	9.386	EPSD	TCGA;ICGC	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q8WWI1	LMO7	O14757	CHEK1	S925	P928L	928	Missense	distal	3	no	8.062	7.299	EPSD	TCGA;ICGC;COSMIC	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q8WWI1	LMO7	O14757	CHEK1	T932	P928L	928	Missense	distal	-4	no	12.357	12.173	EPSD	TCGA;ICGC;COSMIC	5.604	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q9Y6W5	WASF2	P27361	MAPK3	T129	P130S	130	Missense	proximal	1	no	13.089	4.036	EPSD	TCGA;ICGC	9.358	Loss
CMGC_MAPK_ERK1_MAPK3_ST	Q9Y6W5	WASF2	P27361	MAPK3	T129	L136V	136	Missense	distal	7	no	13.089	13.137	EPSD	TCGA;ICGC;COSMIC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q9Y6W5	WASF2	P27361	MAPK3	T129	L133I	133	Missense	distal	4	no	13.089	12.951	EPSD	TCGA;ICGC;COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q9Y6W5	WASF2	P27361	MAPK3	T137	P130S	130	Missense	distal	-7	no	14.841	14.803	EPSD	TCGA;ICGC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q9Y6W5	WASF2	P27361	MAPK3	T137	L136V	136	Missense	proximal	-1	no	14.841	14.845	EPSD	TCGA;ICGC;COSMIC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q9Y6W5	WASF2	P27361	MAPK3	T137	L133I	133	Missense	distal	-4	no	14.841	14.821	EPSD	TCGA;ICGC;COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q9Y6W5	WASF2	P27361	MAPK3	S257	F262L	262	Missense	distal	5	no	16.804	16.957	EPSD	TCGA;ICGC;COSMIC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q9Y6W5	WASF2	P27361	MAPK3	S257	S254T	254	Missense	distal	-3	no	16.804	16.774	EPSD	TCGA;ICGC;COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q9Y6W5	WASF2	P27361	MAPK3	S257	S263F	263	Missense	distal	6	no	16.804	16.090	EPSD	TCGA;ICGC;COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q9Y6W5	WASF2	P27361	MAPK3	S257	Q251R	251	Missense	distal	-6	no	16.804	16.794	EPSD	TCGA;ICGC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q9Y6W5	WASF2	P27361	MAPK3	S257	D253E	253	Missense	distal	-4	no	16.804	16.815	EPSD	TCGA;ICGC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q9Y6W5	WASF2	P27361	MAPK3	S259	F262L	262	Missense	distal	3	no	16.799	16.831	EPSD	TCGA;ICGC;COSMIC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q9Y6W5	WASF2	P27361	MAPK3	S259	S254T	254	Missense	distal	-5	no	16.799	16.783	EPSD	TCGA;ICGC;COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q9Y6W5	WASF2	P27361	MAPK3	S259	S263F	263	Missense	distal	4	no	16.799	16.384	EPSD	TCGA;ICGC;COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q9Y6W5	WASF2	P27361	MAPK3	S259	D253E	253	Missense	distal	-6	no	16.799	16.843	EPSD	TCGA;ICGC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q9Y6W5	WASF2	P27361	MAPK3	S296	P297L	297	Missense	proximal	1	no	16.695	7.656	EPSD	TCGA;ICGC;COSMIC	9.358	Loss
CMGC_MAPK_ERK1_MAPK3_ST	Q9Y6W5	WASF2	P27361	MAPK3	S296	P297S	297	Missense	proximal	1	no	16.695	7.641	EPSD	TCGA;ICGC	9.358	Loss
CMGC_MAPK_ERK1_MAPK3_ST	Q9Y6W5	WASF2	P27361	MAPK3	S343	G345W	345	Missense	proximal	2	no	15.818	15.762	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q9Y6W5	WASF2	P27361	MAPK3	S343	G345E	345	Missense	proximal	2	no	15.818	15.826	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q9Y6W5	WASF2	P27361	MAPK3	T346	S351L	351	Missense	distal	5	no	17.447	17.176	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q9Y6W5	WASF2	P27361	MAPK3	T346	G345W	345	Missense	proximal	-1	no	17.447	17.233	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q9Y6W5	WASF2	P27361	MAPK3	T346	G345E	345	Missense	proximal	-1	no	17.447	17.488	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q9Y6W5	WASF2	P27361	MAPK3	S351	S351L	351	Missense	central	0	yes	17.575	0.000	PhosphoSitePlus;EPSD	TCGA;ICGC;COSMIC	9.358	Loss
CMGC_MAPK_ERK1_MAPK3_ST	Q9Y6W5	WASF2	P27361	MAPK3	S351	G345W	345	Missense	distal	-6	no	17.575	16.955	PhosphoSitePlus;EPSD	TCGA;ICGC;COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q9Y6W5	WASF2	P27361	MAPK3	S351	G345E	345	Missense	distal	-6	no	17.575	17.621	PhosphoSitePlus;EPSD	TCGA;ICGC;COSMIC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q9Y6W5	WASF2	P27361	MAPK3	S484	E485Q	485	Missense	proximal	1	no	11.190	12.495	EPSD	TCGA;ICGC;COSMIC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q9Y6W5	WASF2	P27361	MAPK3	S489	E485Q	485	Missense	distal	-4	no	11.136	11.094	EPSD	TCGA;ICGC;COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P11388	TOP2A	P27361	MAPK3	S4	E2K	2	Missense	proximal	-2	no	14.357	13.663	EPSD	TCGA	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P11388	TOP2A	P27361	MAPK3	S4	P5L	5	Missense	proximal	1	no	14.357	5.319	EPSD	TCGA;ICGC;COSMIC	9.358	Loss
CMGC_MAPK_ERK1_MAPK3_ST	P11388	TOP2A	P27361	MAPK3	S387	S387R	387	Missense	central	0	yes	12.402	0.000	EPSD	TCGA	9.358	Loss
CMGC_MAPK_ERK1_MAPK3_ST	P11388	TOP2A	P27361	MAPK3	T950	N945I	945	Missense	distal	-5	no	16.507	16.453	EPSD	TCGA	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P11388	TOP2A	P27361	MAPK3	T950	T955A	955	Missense	distal	5	no	16.507	16.387	EPSD	TCGA;ICGC;COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P11388	TOP2A	P27361	MAPK3	T950	E948G	948	Missense	proximal	-2	no	16.507	16.036	EPSD	TCGA;ICGC;COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P11388	TOP2A	P27361	MAPK3	T950	E948D	948	Missense	proximal	-2	no	16.507	16.546	EPSD	TCGA;ICGC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P11388	TOP2A	P27361	MAPK3	S1115	S1117C	1117	Missense	proximal	2	no	11.365	11.303	EPSD	TCGA;ICGC;COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P11388	TOP2A	P27361	MAPK3	S1115	D1116N	1116	Missense	proximal	1	no	11.365	5.878	EPSD	TCGA;ICGC;COSMIC	9.358	Loss
CMGC_MAPK_ERK1_MAPK3_ST	P11388	TOP2A	P27361	MAPK3	S1115	S1117F	1117	Missense	proximal	2	no	11.365	11.314	EPSD	TCGA;ICGC;COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P11388	TOP2A	P27361	MAPK3	S1115	D1120Y	1120	Missense	distal	5	no	11.365	11.190	EPSD	TCGA;ICGC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P11388	TOP2A	P27361	MAPK3	T1124	D1130H	1130	Missense	distal	6	no	9.508	9.462	EPSD	TCGA;ICGC;COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P11388	TOP2A	P27361	MAPK3	T1124	S1117C	1117	Missense	distal	-7	no	9.508	9.778	EPSD	TCGA;ICGC;COSMIC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P11388	TOP2A	P27361	MAPK3	T1124	S1117F	1117	Missense	distal	-7	no	9.508	9.727	EPSD	TCGA;ICGC;COSMIC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P11388	TOP2A	P27361	MAPK3	T1124	D1120Y	1120	Missense	distal	-4	no	9.508	9.440	EPSD	TCGA;ICGC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P11388	TOP2A	P27361	MAPK3	T1124	M1131V	1131	Missense	distal	7	no	9.508	9.376	EPSD	TCGA;ICGC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P11388	TOP2A	P27361	MAPK3	S1213	R1215H	1215	Missense	proximal	2	no	14.675	14.672	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P11388	TOP2A	P27361	MAPK3	S1213	E1209D	1209	Missense	distal	-4	no	14.675	14.663	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P11388	TOP2A	P27361	MAPK3	S1247	E1245K	1245	Missense	proximal	-2	no	16.348	15.654	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P11388	TOP2A	P27361	MAPK3	S1247	E1242G	1242	Missense	distal	-5	no	16.348	16.339	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P11388	TOP2A	P27361	MAPK3	S1354	P1350L	1350	Missense	distal	-4	no	16.824	16.711	EPSD;PhosphoSitePlus	TCGA	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P11388	TOP2A	P27361	MAPK3	S1361	E1368Q	1368	Missense	distal	7	no	15.263	15.358	PhosphoSitePlus;EPSD	TCGA;ICGC;COSMIC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P11388	TOP2A	P27361	MAPK3	S1377	E1380K	1380	Missense	distal	3	no	9.456	9.445	EPSD	TCGA;ICGC;COSMIC;GDSC;CCLE	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P11388	TOP2A	P27361	MAPK3	S1377	D1382H	1382	Missense	distal	5	no	9.456	9.390	EPSD	TCGA;ICGC;COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q07820	MCL1	P27361	MAPK3	S121	E123K	123	Missense	proximal	2	no	14.022	14.015	EPSD	TCGA;ICGC;COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q07820	MCL1	P27361	MAPK3	T163	S162W	162	Missense	proximal	-1	no	16.774	16.494	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P15056	BRAF	P27361	MAPK3	S151	R146W	146	Missense	distal	-5	no	14.464	14.311	EPSD	TCGA;ICGC;COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P15056	BRAF	P27361	MAPK3	S316	S317F	317	Missense	proximal	1	no	6.647	9.486	EPSD	TCGA;ICGC;COSMIC	9.358	Gain
CMGC_MAPK_ERK1_MAPK3_ST	P15056	BRAF	P27361	MAPK3	S317	L312I	312	Missense	distal	-5	no	15.604	15.570	EPSD	TCGA;ICGC;COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P15056	BRAF	P27361	MAPK3	S317	A320T	320	Missense	distal	3	no	15.604	15.635	EPSD	TCGA;ICGC;COSMIC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P15056	BRAF	P27361	MAPK3	S317	P318L	318	Missense	proximal	1	no	15.604	6.566	EPSD	TCGA;ICGC;COSMIC	9.358	Loss
CMGC_MAPK_ERK1_MAPK3_ST	P15056	BRAF	P27361	MAPK3	S317	P318S	318	Missense	proximal	1	no	15.604	6.551	EPSD	TCGA;ICGC;COSMIC	9.358	Loss
CMGC_MAPK_ERK1_MAPK3_ST	P15056	BRAF	P27361	MAPK3	S317	S317F	317	Missense	central	0	yes	15.604	0.000	EPSD	TCGA;ICGC;COSMIC	9.358	Loss
CMGC_MAPK_ERK1_MAPK3_ST	P15056	BRAF	P27361	MAPK3	S319	L312I	312	Missense	distal	-7	no	11.603	11.649	EPSD	TCGA;ICGC;COSMIC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P15056	BRAF	P27361	MAPK3	S319	A320T	320	Missense	proximal	1	no	11.603	11.965	EPSD	TCGA;ICGC;COSMIC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P15056	BRAF	P27361	MAPK3	S319	P318L	318	Missense	proximal	-1	no	11.603	11.508	EPSD	TCGA;ICGC;COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P15056	BRAF	P27361	MAPK3	S319	P318S	318	Missense	proximal	-1	no	11.603	11.597	EPSD	TCGA;ICGC;COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P15056	BRAF	P27361	MAPK3	S319	S317F	317	Missense	proximal	-2	no	11.603	10.303	EPSD	TCGA;ICGC;COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P15056	BRAF	P27361	MAPK3	S335	P341L	341	Missense	distal	6	no	16.219	15.992	EPSD	TCGA;ICGC;COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P15056	BRAF	P27361	MAPK3	T401	T401I	401	Missense	central	0	yes	15.379	0.000	PhosphoSitePlus;EPSD	TCGA;ICGC;COSMIC	9.358	Loss
CMGC_MAPK_ERK1_MAPK3_ST	P15056	BRAF	P27361	MAPK3	T401	G397S	397	Missense	distal	-4	no	15.379	15.418	PhosphoSitePlus;EPSD	TCGA;ICGC;COSMIC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P15056	BRAF	P27361	MAPK3	T401	T401A	401	Missense	central	0	yes	15.379	0.000	PhosphoSitePlus;EPSD	TCGA;ICGC;COSMIC	9.358	Loss
CMGC_MAPK_ERK1_MAPK3_ST	P15056	BRAF	P27361	MAPK3	S419	S419Y	419	Missense	central	0	yes	14.652	0.000	EPSD	TCGA;ICGC;COSMIC	9.358	Loss
CMGC_MAPK_ERK1_MAPK3_ST	P15056	BRAF	P27361	MAPK3	S467	G469A	469	Missense	proximal	2	no	10.411	10.389	EPSD	TCGA;ICGC;COSMIC;GDSC;CCLE	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P15056	BRAF	P27361	MAPK3	S467	G466V	466	Missense	proximal	-1	no	10.411	10.393	EPSD	TCGA;ICGC;COSMIC;GDSC;CCLE	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P15056	BRAF	P27361	MAPK3	S467	G466E	466	Missense	proximal	-1	no	10.411	10.452	EPSD	TCGA;ICGC;COSMIC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P15056	BRAF	P27361	MAPK3	S467	G469V	469	Missense	proximal	2	no	10.411	10.402	EPSD	TCGA;ICGC;COSMIC;GDSC;CCLE	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P15056	BRAF	P27361	MAPK3	S467	G466A	466	Missense	proximal	-1	no	10.411	10.343	EPSD	TCGA;ICGC;COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P15056	BRAF	P27361	MAPK3	S467	G464V	464	Missense	distal	-3	no	10.411	10.371	EPSD	TCGA;ICGC;COSMIC;GDSC;CCLE	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P15056	BRAF	P27361	MAPK3	S467	G469R	469	Missense	proximal	2	no	10.411	10.415	EPSD	TCGA;ICGC;COSMIC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P15056	BRAF	P27361	MAPK3	S467	R462T	462	Missense	distal	-5	no	10.411	10.441	EPSD	TCGA;ICGC;COSMIC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P15056	BRAF	P27361	MAPK3	S467	F468C	468	Missense	proximal	1	no	10.411	1.317	EPSD	TCGA;ICGC;COSMIC	9.358	Loss
CMGC_MAPK_ERK1_MAPK3_ST	P15056	BRAF	P27361	MAPK3	S467	S467L	467	Missense	central	0	yes	10.411	0.000	EPSD	TCGA;ICGC;COSMIC	9.358	Loss
CMGC_MAPK_ERK1_MAPK3_ST	P15056	BRAF	P27361	MAPK3	S467	G469E	469	Missense	proximal	2	no	10.411	10.419	EPSD	TCGA;ICGC;COSMIC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P15056	BRAF	P27361	MAPK3	S467	V471I	471	Missense	distal	4	no	10.411	10.293	EPSD	TCGA;ICGC;COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P15056	BRAF	P27361	MAPK3	S467	G464E	464	Missense	distal	-3	no	10.411	10.424	EPSD	TCGA;ICGC;COSMIC;GDSC;CCLE	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P15056	BRAF	P27361	MAPK3	S675	L678I	678	Missense	distal	3	no	15.482	15.463	EPSD	TCGA;ICGC;COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P15056	BRAF	P27361	MAPK3	S732	L733F	733	Missense	proximal	1	no	6.932	9.757	EPSD	TCGA;ICGC;COSMIC	9.358	Gain
CMGC_MAPK_ERK1_MAPK3_ST	P15056	BRAF	P27361	MAPK3	S750	P751A	751	Missense	proximal	1	no	17.108	7.869	EPSD	TCGA;ICGC;COSMIC	9.358	Loss
CMGC_MAPK_ERK1_MAPK3_ST	P15056	BRAF	P27361	MAPK3	S750	A747D	747	Missense	distal	-3	no	17.108	17.177	EPSD	TCGA;ICGC;COSMIC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P15056	BRAF	P27361	MAPK3	T753	P751A	751	Missense	proximal	-2	no	19.962	17.611	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P15056	BRAF	P27361	MAPK3	T753	A747D	747	Missense	distal	-6	no	19.962	20.217	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P04626	ERBB2	P27361	MAPK3	S196	S196F	196	Missense	central	0	yes	18.475	0.000	EPSD	TCGA;COSMIC	9.358	Loss
CMGC_MAPK_ERK1_MAPK3_ST	P04626	ERBB2	P27361	MAPK3	S196	R203C	203	Missense	distal	7	no	18.475	18.917	EPSD	TCGA;COSMIC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P04626	ERBB2	P27361	MAPK3	T701	V697L	697	Missense	distal	-4	no	18.033	18.045	PhosphoSitePlus	TCGA;COSMIC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P04626	ERBB2	P27361	MAPK3	S760	L755S	755	Missense	distal	-5	no	15.436	15.496	EPSD	TCGA;COSMIC;GDSC;CCLE	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P04626	ERBB2	P27361	MAPK3	S760	I767M	767	Missense	distal	7	no	15.436	15.488	EPSD	TCGA;COSMIC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P04626	ERBB2	P27361	MAPK3	S760	L755M	755	Missense	distal	-5	no	15.436	15.377	EPSD	TCGA;COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P04626	ERBB2	P27361	MAPK3	S760	L755W	755	Missense	distal	-5	no	15.436	15.296	EPSD	TCGA;COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P04626	ERBB2	P27361	MAPK3	S760	R756K	756	Missense	distal	-4	no	15.436	15.429	EPSD	TCGA;COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P04626	ERBB2	P27361	MAPK3	S760	I767F	767	Missense	distal	7	no	15.436	15.528	EPSD	TCGA;COSMIC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P04626	ERBB2	P27361	MAPK3	S779	V777L	777	Missense	proximal	-2	no	16.319	16.589	EPSD	TCGA;COSMIC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P04626	ERBB2	P27361	MAPK3	S779	G776S	776	Missense	distal	-3	no	16.319	16.352	EPSD	TCGA;COSMIC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P04626	ERBB2	P27361	MAPK3	S779	V777M	777	Missense	proximal	-2	no	16.319	15.219	EPSD	TCGA;COSMIC;GDSC;CCLE	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P04626	ERBB2	P27361	MAPK3	S779	R784C	784	Missense	distal	5	no	16.319	15.940	EPSD	TCGA;COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P04626	ERBB2	P27361	MAPK3	S779	G776V	776	Missense	distal	-3	no	16.319	16.280	EPSD	TCGA;COSMIC;GDSC;CCLE	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P04626	ERBB2	P27361	MAPK3	S998	L994V	994	Missense	distal	-4	no	18.499	18.487	EPSD	TCGA	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P04626	ERBB2	P27361	MAPK3	S998	D993N	993	Missense	distal	-5	no	18.499	18.493	EPSD	TCGA;COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P04626	ERBB2	P27361	MAPK3	S1073	E1079K	1079	Missense	distal	6	no	17.843	17.767	EPSD	TCGA;COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P04626	ERBB2	P27361	MAPK3	S1073	A1070V	1070	Missense	distal	-3	no	17.843	17.862	EPSD	TCGA;COSMIC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P04626	ERBB2	P27361	MAPK3	S1073	G1080W	1080	Missense	distal	7	no	17.843	18.450	EPSD	TCGA;COSMIC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P04626	ERBB2	P27361	MAPK3	S1107	R1111W	1111	Missense	distal	4	no	14.208	13.741	EPSD	TCGA;COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P04626	ERBB2	P27361	MAPK3	S1134	V1128I	1128	Missense	distal	-6	no	16.818	16.749	EPSD	TCGA;COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P04626	ERBB2	P27361	MAPK3	S1151	R1146Q	1146	Missense	distal	-5	no	17.420	17.413	EPSD	TCGA;COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P04626	ERBB2	P27361	MAPK3	T1198	P1199T	1199	Missense	proximal	1	no	15.781	6.904	EPSD	TCGA;COSMIC	9.358	Loss
CMGC_MAPK_ERK1_MAPK3_ST	P04626	ERBB2	P27361	MAPK3	S1214	H1208Y	1208	Missense	distal	-6	no	16.479	16.390	EPSD	TCGA;COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P04626	ERBB2	P27361	MAPK3	S1214	N1219S	1219	Missense	distal	5	no	16.479	16.601	EPSD	TCGA;COSMIC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P04626	ERBB2	P27361	MAPK3	S1214	S1214N	1214	Missense	central	0	yes	16.479	0.000	EPSD	TCGA;COSMIC;CCLE	9.358	Loss
CMGC_MAPK_ERK1_MAPK3_ST	P04626	ERBB2	P27361	MAPK3	S1235	P1234S	1234	Missense	proximal	-1	no	11.082	11.076	EPSD	TCGA;COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P04626	ERBB2	P27361	MAPK3	S1235	P1233S	1233	Missense	proximal	-2	no	11.082	10.006	EPSD	TCGA;COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P04626	ERBB2	P27361	MAPK3	S1235	P1241H	1241	Missense	distal	6	no	11.082	10.988	EPSD	TCGA;COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P04626	ERBB2	P27361	MAPK3	T1236	P1234S	1234	Missense	proximal	-2	no	12.477	11.401	EPSD	TCGA;COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P04626	ERBB2	P27361	MAPK3	T1236	P1233S	1233	Missense	distal	-3	no	12.477	12.468	EPSD	TCGA;COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P04626	ERBB2	P27361	MAPK3	T1236	P1241H	1241	Missense	distal	5	no	12.477	12.412	EPSD	TCGA;COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P04626	ERBB2	P27361	MAPK3	T1240	E1244Q	1244	Missense	distal	4	no	17.623	17.532	EPSD	TCGA;COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P04626	ERBB2	P27361	MAPK3	T1240	E1247A	1247	Missense	distal	7	no	17.623	17.865	EPSD	TCGA;COSMIC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P04626	ERBB2	P27361	MAPK3	T1240	P1234S	1234	Missense	distal	-6	no	17.623	17.708	EPSD	TCGA;COSMIC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P04626	ERBB2	P27361	MAPK3	T1240	P1233S	1233	Missense	distal	-7	no	17.623	17.586	EPSD	TCGA;COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P04626	ERBB2	P27361	MAPK3	T1240	P1241H	1241	Missense	proximal	1	no	17.623	9.867	EPSD	TCGA;COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P04626	ERBB2	P27361	MAPK3	T1242	E1244Q	1244	Missense	proximal	2	no	10.287	10.274	EPSD	TCGA;COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P04626	ERBB2	P27361	MAPK3	T1242	E1247A	1247	Missense	distal	5	no	10.287	10.056	EPSD	TCGA;COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P04626	ERBB2	P27361	MAPK3	T1242	P1241H	1241	Missense	proximal	-1	no	10.287	10.242	EPSD	TCGA;COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P10636	MAPT	P27361	MAPK3	S46	T52I	52	Missense	distal	6	no	15.672	15.258	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P10636	MAPT	P27361	MAPK3	S46	P47S	47	Missense	proximal	1	no	15.672	6.619	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	9.358	Loss
CMGC_MAPK_ERK1_MAPK3_ST	P10636	MAPT	P27361	MAPK3	S46	P47L	47	Missense	proximal	1	no	15.672	6.634	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	9.358	Loss
CMGC_MAPK_ERK1_MAPK3_ST	P10636	MAPT	P27361	MAPK3	S46	G42C	42	Missense	distal	-4	no	15.672	15.473	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P10636	MAPT	P27361	MAPK3	T50	D54E	54	Missense	distal	4	no	16.613	16.632	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P10636	MAPT	P27361	MAPK3	T50	T52I	52	Missense	proximal	2	no	16.613	16.589	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P10636	MAPT	P27361	MAPK3	T50	P47S	47	Missense	distal	-3	no	16.613	16.604	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P10636	MAPT	P27361	MAPK3	T50	P47L	47	Missense	distal	-3	no	16.613	16.528	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P10636	MAPT	P27361	MAPK3	T50	G55R	55	Missense	distal	5	no	16.613	16.533	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P10636	MAPT	P27361	MAPK3	S68	A66S	66	Missense	proximal	-2	no	9.012	10.286	EPSD	TCGA;ICGC;COSMIC	9.358	Gain
CMGC_MAPK_ERK1_MAPK3_ST	P10636	MAPT	P27361	MAPK3	T69	A72V	72	Missense	distal	3	no	15.297	15.303	EPSD	TCGA;ICGC;COSMIC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P10636	MAPT	P27361	MAPK3	T69	A66S	66	Missense	distal	-3	no	15.297	15.388	EPSD	TCGA;ICGC;COSMIC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P10636	MAPT	P27361	MAPK3	T111	E117K	117	Missense	distal	6	no	15.249	15.173	EPSD	TCGA;ICGC;COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P10636	MAPT	P27361	MAPK3	T111	A118V	118	Missense	distal	7	no	15.249	15.221	EPSD	TCGA;ICGC;COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P10636	MAPT	P27361	MAPK3	S228	S232Y	232	Missense	distal	4	no	17.196	16.979	EPSD	TCGA;ICGC;COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P10636	MAPT	P27361	MAPK3	S228	D223Y	223	Missense	distal	-5	no	17.196	17.167	EPSD	TCGA;ICGC;COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P10636	MAPT	P27361	MAPK3	S228	S227F	227	Missense	proximal	-1	no	17.196	16.991	EPSD	TCGA;ICGC;COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P10636	MAPT	P27361	MAPK3	S228	P234L	234	Missense	distal	6	no	17.196	16.969	EPSD	TCGA;ICGC;COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P10636	MAPT	P27361	MAPK3	S232	S232Y	232	Missense	central	0	yes	16.576	0.000	EPSD	TCGA;ICGC;COSMIC	9.358	Loss
CMGC_MAPK_ERK1_MAPK3_ST	P10636	MAPT	P27361	MAPK3	S232	S227F	227	Missense	distal	-5	no	16.576	16.442	EPSD	TCGA;ICGC;COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P10636	MAPT	P27361	MAPK3	S232	P234L	234	Missense	proximal	2	no	16.576	16.555	EPSD	TCGA;ICGC;COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P10636	MAPT	P27361	MAPK3	S238	S232Y	232	Missense	distal	-6	no	16.113	15.860	EPSD	TCGA;ICGC;COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P10636	MAPT	P27361	MAPK3	S238	A240T	240	Missense	proximal	2	no	16.113	16.140	EPSD	TCGA;ICGC;COSMIC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P10636	MAPT	P27361	MAPK3	S238	P234L	234	Missense	distal	-4	no	16.113	16.000	EPSD	TCGA;ICGC;COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P10636	MAPT	P27361	MAPK3	S238	R244Q	244	Missense	distal	6	no	16.113	16.044	EPSD	TCGA;ICGC;COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P10636	MAPT	P27361	MAPK3	S411	P415L	415	Missense	distal	4	no	14.840	14.686	EPSD	TCGA;ICGC;COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P10636	MAPT	P27361	MAPK3	T416	P415L	415	Missense	proximal	-1	no	14.703	14.608	EPSD	TCGA;ICGC;COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P10636	MAPT	P27361	MAPK3	S428	A430S	430	Missense	proximal	2	no	17.002	17.040	EPSD	TCGA;ICGC;COSMIC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P10636	MAPT	P27361	MAPK3	S428	V431L	431	Missense	distal	3	no	17.002	17.007	EPSD	TCGA;ICGC;COSMIC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P10636	MAPT	P27361	MAPK3	S428	A430V	430	Missense	proximal	2	no	17.002	17.015	EPSD	TCGA;ICGC;COSMIC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P10636	MAPT	P27361	MAPK3	S438	P436T	436	Missense	proximal	-2	no	20.015	19.029	EPSD	TCGA;ICGC;COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P10636	MAPT	P27361	MAPK3	S438	P436L	436	Missense	proximal	-2	no	20.015	18.631	EPSD	TCGA;ICGC;COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P10636	MAPT	P27361	MAPK3	S438	K440E	440	Missense	proximal	2	no	20.015	20.022	EPSD	TCGA;ICGC;COSMIC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P10636	MAPT	P27361	MAPK3	S438	S443F	443	Missense	distal	5	no	20.015	19.590	EPSD	TCGA;ICGC;COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P10636	MAPT	P27361	MAPK3	S438	V431L	431	Missense	distal	-7	no	20.015	20.011	EPSD	TCGA;ICGC;COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P10636	MAPT	P27361	MAPK3	S438	S444F	444	Missense	distal	6	no	20.015	19.301	EPSD	TCGA;ICGC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P10636	MAPT	P27361	MAPK3	T470	R472Q	472	Missense	proximal	2	no	14.131	14.121	EPSD	TCGA	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P10636	MAPT	P27361	MAPK3	T470	R472W	472	Missense	proximal	2	no	14.131	14.070	EPSD	TCGA;COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P10636	MAPT	P27361	MAPK3	T492	A485T	485	Missense	distal	-7	no	13.516	13.443	EPSD	TCGA;COSMIC;GDSC;CCLE	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P10636	MAPT	P27361	MAPK3	T492	P493Q	493	Missense	proximal	1	no	13.516	5.572	EPSD	TCGA;COSMIC	9.358	Loss
CMGC_MAPK_ERK1_MAPK3_ST	P10636	MAPT	P27361	MAPK3	T498	P493Q	493	Missense	distal	-5	no	16.656	16.608	EPSD	TCGA;COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q13541	EIF4EBP1	P27361	MAPK3	T70	L75M	75	Missense	distal	5	no	16.526	16.406	EPSD	TCGA;ICGC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q13541	EIF4EBP1	P27361	MAPK3	S83	S86N	86	Missense	distal	3	no	15.837	15.816	EPSD	TCGA;ICGC;COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q13541	EIF4EBP1	P27361	MAPK3	S86	S86N	86	Missense	central	0	yes	11.448	0.000	EPSD	TCGA;ICGC;COSMIC	9.358	Loss
CMGC_MAPK_ERK1_MAPK3_ST	Q13541	EIF4EBP1	P27361	MAPK3	S101	A107V	107	Missense	distal	6	no	17.868	17.955	EPSD	TCGA;ICGC;COSMIC;GDSC;CCLE	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q13541	EIF4EBP1	P27361	MAPK3	S112	G109S	109	Missense	distal	-3	no	10.620	10.652	EPSD	TCGA	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q13541	EIF4EBP1	P27361	MAPK3	S112	G109C	109	Missense	distal	-3	no	10.620	10.475	EPSD	TCGA;COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q13541	EIF4EBP1	P27361	MAPK3	S112	A107V	107	Missense	distal	-5	no	10.620	10.643	EPSD	TCGA;ICGC;COSMIC;GDSC;CCLE	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P49715	CEBPA	P27361	MAPK3	S332	R339W	339	Missense	distal	7	no	10.348	10.925	EPSD	TCGA;ICGC;COSMIC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q16828	DUSP6	P27361	MAPK3	S159	S154W	154	Missense	distal	-5	no	16.518	16.319	EPSD;PhosphoSitePlus	TCGA;COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q16828	DUSP6	P27361	MAPK3	S197	P204L	204	Missense	distal	7	no	17.628	17.820	EPSD;PhosphoSitePlus	TCGA;COSMIC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q16828	DUSP6	P27361	MAPK3	S197	S200T	200	Missense	distal	3	no	17.628	17.614	EPSD;PhosphoSitePlus	TCGA;COSMIC;GDSC;CCLE	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q16828	DUSP6	P27361	MAPK3	S197	S194L	194	Missense	distal	-3	no	17.628	17.552	EPSD;PhosphoSitePlus	TCGA;COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q16828	DUSP6	P27361	MAPK3	S205	P204L	204	Missense	proximal	-1	no	9.420	9.326	EPSD	TCGA;COSMIC	9.358	Loss
CMGC_MAPK_ERK1_MAPK3_ST	Q16828	DUSP6	P27361	MAPK3	S205	S200T	200	Missense	distal	-5	no	9.420	9.405	EPSD	TCGA;COSMIC;GDSC;CCLE	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q16828	DUSP6	P27361	MAPK3	S205	P212S	212	Missense	distal	7	no	9.420	9.343	EPSD	TCGA;COSMIC	9.358	Loss
CMGC_MAPK_ERK1_MAPK3_ST	P41235	HNF4A	P27361	MAPK3	S142	D135N	135	Missense	distal	-7	no	9.379	9.403	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P41235	HNF4A	P27361	MAPK3	S167	V160F	160	Missense	distal	-7	no	14.115	14.185	EPSD;PhosphoSitePlus	TCGA	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P41235	HNF4A	P27361	MAPK3	S167	S170C	170	Missense	distal	3	no	14.115	14.029	EPSD;PhosphoSitePlus	TCGA;COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P41235	HNF4A	P27361	MAPK3	S167	G174S	174	Missense	distal	7	no	14.115	13.975	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P41235	HNF4A	P27361	MAPK3	S378	D381N	381	Missense	distal	3	no	16.130	16.120	EPSD	TCGA;ICGC;COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P41235	HNF4A	P27361	MAPK3	S378	A382S	382	Missense	distal	4	no	16.130	16.462	EPSD	TCGA;ICGC;COSMIC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P41235	HNF4A	P27361	MAPK3	S378	H384N	384	Missense	distal	6	no	16.130	16.124	EPSD	TCGA;COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P41235	HNF4A	P27361	MAPK3	S378	G377E	377	Missense	proximal	-1	no	16.130	16.172	EPSD	TCGA;ICGC;COSMIC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P41235	HNF4A	P27361	MAPK3	S378	S380N	380	Missense	proximal	2	no	16.130	16.113	EPSD	TCGA;COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P41235	HNF4A	P27361	MAPK3	S378	G376R	376	Missense	proximal	-2	no	16.130	16.847	EPSD	TCGA;ICGC;COSMIC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P41235	HNF4A	P27361	MAPK3	S378	S380G	380	Missense	proximal	2	no	16.130	16.113	EPSD	TCGA;COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P41235	HNF4A	P27361	MAPK3	S378	D381V	381	Missense	distal	3	no	16.130	16.104	EPSD	TCGA;ICGC;COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P41235	HNF4A	P27361	MAPK3	T429	P433S	433	Missense	distal	4	no	13.500	13.549	EPSD	TCGA;COSMIC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P41235	HNF4A	P27361	MAPK3	T429	G425R	425	Missense	distal	-4	no	13.500	13.461	EPSD	TCGA;COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P41235	HNF4A	P27361	MAPK3	T429	R422Q	422	Missense	distal	-7	no	13.500	13.499	EPSD	TCGA;COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P41235	HNF4A	P27361	MAPK3	T429	T432I	432	Missense	distal	3	no	13.500	13.462	EPSD	TCGA;COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P41235	HNF4A	P27361	MAPK3	T432	P433S	433	Missense	proximal	1	no	17.272	8.219	EPSD	TCGA;COSMIC	9.358	Loss
CMGC_MAPK_ERK1_MAPK3_ST	P41235	HNF4A	P27361	MAPK3	T432	G425R	425	Missense	distal	-7	no	17.272	17.318	EPSD	TCGA;COSMIC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P41235	HNF4A	P27361	MAPK3	T432	T432I	432	Missense	central	0	yes	17.272	0.000	EPSD	TCGA;COSMIC	9.358	Loss
CMGC_MAPK_ERK1_MAPK3_ST	P41235	HNF4A	P27361	MAPK3	S436	S443Y	443	Missense	distal	7	no	15.690	15.945	EPSD	TCGA;COSMIC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P41235	HNF4A	P27361	MAPK3	S436	P433S	433	Missense	distal	-3	no	15.690	15.682	EPSD	TCGA;COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P41235	HNF4A	P27361	MAPK3	S436	G442E	442	Missense	distal	6	no	15.690	15.791	EPSD	TCGA;COSMIC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P41235	HNF4A	P27361	MAPK3	S436	T432I	432	Missense	distal	-4	no	15.690	15.589	EPSD	TCGA;COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P41235	HNF4A	P27361	MAPK3	T455	V457I	457	Missense	proximal	2	no	9.549	9.539	EPSD	TCGA;COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P41235	HNF4A	P27361	MAPK3	T455	V453I	453	Missense	proximal	-2	no	9.549	9.365	EPSD	TCGA;COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P41235	HNF4A	P27361	MAPK3	S461	V457I	457	Missense	distal	-4	no	10.418	10.411	EPSD;PhosphoSitePlus	TCGA;COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P41235	HNF4A	P27361	MAPK3	S461	T467A	467	Missense	distal	6	no	10.418	10.047	EPSD;PhosphoSitePlus	TCGA	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q9NYV6	RRN3	P27361	MAPK3	S44	R51W	51	Missense	distal	7	no	15.208	15.784	EPSD	TCGA;ICGC;COSMIC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q9NYV6	RRN3	P27361	MAPK3	S44	R47S	47	Missense	distal	3	no	15.208	15.230	EPSD	TCGA;ICGC;COSMIC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q9NYV6	RRN3	P27361	MAPK3	S172	E175K	175	Missense	distal	3	no	10.486	10.476	EPSD	TCGA;ICGC;COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q9NYV6	RRN3	P27361	MAPK3	S172	D174E	174	Missense	proximal	2	no	10.486	10.489	EPSD	TCGA;ICGC;COSMIC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q9NYV6	RRN3	P27361	MAPK3	T200	R195I	195	Missense	distal	-5	no	16.458	16.409	EPSD	TCGA;ICGC;COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q9NYV6	RRN3	P27361	MAPK3	S409	A402T	402	Missense	distal	-7	no	10.269	10.195	EPSD	TCGA;ICGC;COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q9NYV6	RRN3	P27361	MAPK3	T623	V619M	619	Missense	distal	-4	no	16.050	16.022	EPSD	TCGA;COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q9NYV6	RRN3	P27361	MAPK3	S625	F631L	631	Missense	distal	6	no	9.466	9.824	EPSD	TCGA;COSMIC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q9NYV6	RRN3	P27361	MAPK3	S625	V619M	619	Missense	distal	-6	no	9.466	9.374	EPSD	TCGA;COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q9NYV6	RRN3	P27361	MAPK3	S626	F631L	631	Missense	distal	5	no	12.891	13.045	EPSD	TCGA;COSMIC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q9NYV6	RRN3	P27361	MAPK3	S626	V619M	619	Missense	distal	-7	no	12.891	12.947	EPSD	TCGA;COSMIC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q9NYV6	RRN3	P27361	MAPK3	S633	S640F	640	Missense	distal	7	no	18.912	19.403	PhosphoSitePlus	TCGA;COSMIC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q9NYV6	RRN3	P27361	MAPK3	S633	F631L	631	Missense	proximal	-2	no	18.912	19.904	PhosphoSitePlus	TCGA;COSMIC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q9NYV6	RRN3	P27361	MAPK3	S635	S640F	640	Missense	distal	5	no	10.745	10.320	EPSD	TCGA;COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q9NYV6	RRN3	P27361	MAPK3	S635	P641S	641	Missense	distal	6	no	10.745	10.875	EPSD	TCGA;COSMIC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q9NYV6	RRN3	P27361	MAPK3	S635	F631L	631	Missense	distal	-4	no	10.745	10.794	EPSD	TCGA;COSMIC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q9NYV6	RRN3	P27361	MAPK3	S636	S640F	640	Missense	distal	4	no	11.145	10.731	EPSD	TCGA;COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q9NYV6	RRN3	P27361	MAPK3	S636	P641S	641	Missense	distal	5	no	11.145	11.188	EPSD	TCGA;COSMIC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q9NYV6	RRN3	P27361	MAPK3	S636	F631L	631	Missense	distal	-5	no	11.145	11.220	EPSD	TCGA;COSMIC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q9NYV6	RRN3	P27361	MAPK3	S637	S640F	640	Missense	distal	3	no	10.512	10.447	EPSD	TCGA;COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q9NYV6	RRN3	P27361	MAPK3	S637	P641S	641	Missense	distal	4	no	10.512	10.560	EPSD	TCGA;COSMIC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q9NYV6	RRN3	P27361	MAPK3	S637	F631L	631	Missense	distal	-6	no	10.512	10.647	EPSD	TCGA;COSMIC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q9NYV6	RRN3	P27361	MAPK3	S640	S640F	640	Missense	central	0	yes	17.471	0.000	EPSD	TCGA;COSMIC	9.358	Loss
CMGC_MAPK_ERK1_MAPK3_ST	Q9NYV6	RRN3	P27361	MAPK3	S640	P641S	641	Missense	proximal	1	no	17.471	8.418	EPSD	TCGA;COSMIC	9.358	Loss
CMGC_MAPK_ERK1_MAPK3_ST	Q9NYV6	RRN3	P27361	MAPK3	S649	S649I	649	Missense	central	0	yes	20.025	0.000	EPSD	TCGA;COSMIC	9.358	Loss
CMGC_MAPK_ERK1_MAPK3_ST	P07101	TH	P27361	MAPK3	T3	P4L	4	Missense	proximal	1	no	12.306	3.268	EPSD	TCGA;ICGC;COSMIC;GDSC;CCLE	9.358	Loss
CMGC_MAPK_ERK1_MAPK3_ST	P07101	TH	P27361	MAPK3	T8	R15H	15	Missense	distal	7	no	13.260	13.228	EPSD	TCGA;ICGC;COSMIC;GDSC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P07101	TH	P27361	MAPK3	T8	P4L	4	Missense	distal	-4	no	13.260	13.147	EPSD	TCGA;ICGC;COSMIC;GDSC;CCLE	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P07101	TH	P27361	MAPK3	S62	R64W	64	Missense	proximal	2	no	17.063	17.002	EPSD;PhosphoSitePlus	TCGA;COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P07101	TH	P27361	MAPK3	S62	P63T	63	Missense	proximal	1	no	17.063	8.186	EPSD;PhosphoSitePlus	TCGA;COSMIC	9.358	Loss
CMGC_MAPK_ERK1_MAPK3_ST	P07101	TH	P27361	MAPK3	S62	P63L	63	Missense	proximal	1	no	17.063	8.025	EPSD;PhosphoSitePlus	TCGA;COSMIC	9.358	Loss
CMGC_MAPK_ERK1_MAPK3_ST	P07101	TH	P27361	MAPK3	S62	P63S	63	Missense	proximal	1	no	17.063	8.009	EPSD;PhosphoSitePlus	TCGA;COSMIC	9.358	Loss
CMGC_MAPK_ERK1_MAPK3_ST	P07101	TH	P27361	MAPK3	S118	S125L	125	Missense	distal	7	no	17.120	17.389	EPSD	TCGA;COSMIC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P07101	TH	P27361	MAPK3	S118	R120M	120	Missense	proximal	2	no	17.120	17.088	EPSD	TCGA;COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P07101	TH	P27361	MAPK3	S118	A111T	111	Missense	distal	-7	no	17.120	17.046	EPSD	TCGA	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P07101	TH	P27361	MAPK3	S502	I497M	497	Missense	distal	-5	no	17.074	17.050	EPSD	TCGA;COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P07101	TH	P27361	MAPK3	S502	R508H	508	Missense	distal	6	no	17.074	17.093	EPSD	TCGA	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P07101	TH	P27361	MAPK3	S502	R508S	508	Missense	distal	6	no	17.074	17.315	EPSD	TCGA;COSMIC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P07101	TH	P27361	MAPK3	S502	D498N	498	Missense	distal	-4	no	17.074	17.048	EPSD	TCGA;COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P49790	NUP153	P27361	MAPK3	T102	D98N	98	Missense	distal	-4	no	13.795	13.769	EPSD	TCGA;ICGC;COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P49790	NUP153	P27361	MAPK3	T102	G99E	99	Missense	distal	-3	no	13.795	13.808	EPSD	TCGA;ICGC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P49790	NUP153	P27361	MAPK3	T115	A119T	119	Missense	distal	4	no	9.198	9.416	EPSD	TCGA;ICGC	9.358	Gain
CMGC_MAPK_ERK1_MAPK3_ST	P49790	NUP153	P27361	MAPK3	S174	S172C	172	Missense	proximal	-2	no	10.339	7.899	EPSD	TCGA;ICGC;COSMIC	9.358	Loss
CMGC_MAPK_ERK1_MAPK3_ST	P49790	NUP153	P27361	MAPK3	S174	S174Y	174	Missense	central	0	yes	10.339	0.000	EPSD	TCGA;ICGC	9.358	Loss
CMGC_MAPK_ERK1_MAPK3_ST	P49790	NUP153	P27361	MAPK3	S174	N180H	180	Missense	distal	6	no	10.339	10.345	EPSD	TCGA;ICGC;COSMIC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P49790	NUP153	P27361	MAPK3	S209	P210T	210	Missense	proximal	1	no	17.101	8.223	EPSD	TCGA;ICGC;COSMIC	9.358	Loss
CMGC_MAPK_ERK1_MAPK3_ST	P49790	NUP153	P27361	MAPK3	S209	H216Y	216	Missense	distal	7	no	17.101	17.218	EPSD	TCGA;ICGC;COSMIC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P49790	NUP153	P27361	MAPK3	S209	S203L	203	Missense	distal	-6	no	17.101	16.769	EPSD	TCGA;ICGC;COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P49790	NUP153	P27361	MAPK3	S209	L207V	207	Missense	proximal	-2	no	17.101	16.831	EPSD	TCGA;ICGC;COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P49790	NUP153	P27361	MAPK3	S209	R214H	214	Missense	distal	5	no	17.101	17.136	EPSD	TCGA;ICGC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P49790	NUP153	P27361	MAPK3	S215	P210T	210	Missense	distal	-5	no	10.514	10.504	EPSD	TCGA;ICGC;COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P49790	NUP153	P27361	MAPK3	S215	H216Y	216	Missense	proximal	1	no	10.514	11.222	EPSD	TCGA;ICGC;COSMIC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P49790	NUP153	P27361	MAPK3	S215	Q220R	220	Missense	distal	5	no	10.514	10.516	EPSD	TCGA;ICGC;COSMIC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P49790	NUP153	P27361	MAPK3	S215	R214H	214	Missense	proximal	-1	no	10.514	10.517	EPSD	TCGA;ICGC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P49790	NUP153	P27361	MAPK3	S240	G237E	237	Missense	distal	-3	no	16.590	16.603	EPSD	TCGA;ICGC;COSMIC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P49790	NUP153	P27361	MAPK3	S240	S247L	247	Missense	distal	7	no	16.590	16.860	EPSD	TCGA;ICGC;COSMIC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P49790	NUP153	P27361	MAPK3	S240	S240F	240	Missense	central	0	yes	16.590	0.000	EPSD	TCGA;ICGC;COSMIC	9.358	Loss
CMGC_MAPK_ERK1_MAPK3_ST	P49790	NUP153	P27361	MAPK3	S257	P261T	261	Missense	distal	4	no	15.553	15.489	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P49790	NUP153	P27361	MAPK3	S257	P261S	261	Missense	distal	4	no	15.553	15.602	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P49790	NUP153	P27361	MAPK3	S257	P258S	258	Missense	proximal	1	no	15.553	6.500	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	9.358	Loss
CMGC_MAPK_ERK1_MAPK3_ST	P49790	NUP153	P27361	MAPK3	S320	E316Q	316	Missense	distal	-4	no	17.303	17.260	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P49790	NUP153	P27361	MAPK3	S320	R327K	327	Missense	distal	7	no	17.303	17.309	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P49790	NUP153	P27361	MAPK3	S320	R327I	327	Missense	distal	7	no	17.303	17.532	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P49790	NUP153	P27361	MAPK3	S334	L336V	336	Missense	proximal	2	no	14.207	14.205	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P49790	NUP153	P27361	MAPK3	S334	R327K	327	Missense	distal	-7	no	14.207	14.208	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P49790	NUP153	P27361	MAPK3	S334	R327I	327	Missense	distal	-7	no	14.207	14.315	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P49790	NUP153	P27361	MAPK3	S338	L336V	336	Missense	proximal	-2	no	16.571	16.301	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P49790	NUP153	P27361	MAPK3	T369	K371E	371	Missense	proximal	2	no	15.353	15.361	EPSD;PhosphoSitePlus	TCGA;ICGC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P49790	NUP153	P27361	MAPK3	T369	P363S	363	Missense	distal	-6	no	15.353	15.438	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P49790	NUP153	P27361	MAPK3	T388	L387V	387	Missense	proximal	-1	no	14.277	14.281	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P49790	NUP153	P27361	MAPK3	T388	S386Y	386	Missense	proximal	-2	no	14.277	14.043	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P49790	NUP153	P27361	MAPK3	S426	G424D	424	Missense	proximal	-2	no	8.889	9.399	EPSD	TCGA;ICGC;COSMIC	9.358	Gain
CMGC_MAPK_ERK1_MAPK3_ST	P49790	NUP153	P27361	MAPK3	T486	P492S	492	Missense	distal	6	no	10.174	10.304	EPSD	TCGA;ICGC;COSMIC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P49790	NUP153	P27361	MAPK3	T486	S491F	491	Missense	distal	5	no	10.174	9.749	EPSD	TCGA;ICGC;COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P49790	NUP153	P27361	MAPK3	T486	E493D	493	Missense	distal	7	no	10.174	10.176	EPSD	TCGA;ICGC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P49790	NUP153	P27361	MAPK3	S491	P492S	492	Missense	proximal	1	no	15.623	6.570	EPSD	TCGA;ICGC;COSMIC	9.358	Loss
CMGC_MAPK_ERK1_MAPK3_ST	P49790	NUP153	P27361	MAPK3	S491	S491F	491	Missense	central	0	yes	15.623	0.000	EPSD	TCGA;ICGC;COSMIC	9.358	Loss
CMGC_MAPK_ERK1_MAPK3_ST	P49790	NUP153	P27361	MAPK3	S491	E493D	493	Missense	proximal	2	no	15.623	15.621	EPSD	TCGA;ICGC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P49790	NUP153	P27361	MAPK3	S498	P492S	492	Missense	distal	-6	no	15.717	15.801	EPSD	TCGA;ICGC;COSMIC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P49790	NUP153	P27361	MAPK3	S498	S491F	491	Missense	distal	-7	no	15.717	15.936	EPSD	TCGA;ICGC;COSMIC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P49790	NUP153	P27361	MAPK3	S498	S504L	504	Missense	distal	6	no	15.717	15.360	EPSD	TCGA;ICGC;COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P49790	NUP153	P27361	MAPK3	S500	S504L	504	Missense	distal	4	no	16.603	16.400	EPSD	TCGA;ICGC;COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P49790	NUP153	P27361	MAPK3	S500	E493D	493	Missense	distal	-7	no	16.603	16.613	EPSD	TCGA;ICGC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P49790	NUP153	P27361	MAPK3	S516	S516C	516	Missense	central	0	yes	17.006	0.000	PhosphoSitePlus;EPSD	TCGA;ICGC;COSMIC	9.358	Loss
CMGC_MAPK_ERK1_MAPK3_ST	P49790	NUP153	P27361	MAPK3	S516	P517L	517	Missense	proximal	1	no	17.006	7.968	PhosphoSitePlus;EPSD	TCGA;ICGC;COSMIC	9.358	Loss
CMGC_MAPK_ERK1_MAPK3_ST	P49790	NUP153	P27361	MAPK3	S522	S516C	516	Missense	distal	-6	no	16.518	15.959	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P49790	NUP153	P27361	MAPK3	S522	P517L	517	Missense	distal	-5	no	16.518	16.464	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P49790	NUP153	P27361	MAPK3	S522	F527C	527	Missense	distal	5	no	16.518	16.420	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P49790	NUP153	P27361	MAPK3	S529	P530L	530	Missense	proximal	1	no	15.387	6.349	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	9.358	Loss
CMGC_MAPK_ERK1_MAPK3_ST	P49790	NUP153	P27361	MAPK3	S529	F527C	527	Missense	proximal	-2	no	15.387	14.248	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P49790	NUP153	P27361	MAPK3	S573	H575Y	575	Missense	proximal	2	no	9.772	9.766	EPSD	TCGA;ICGC;COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P49790	NUP153	P27361	MAPK3	T588	K587N	587	Missense	proximal	-1	no	14.960	14.967	EPSD	TCGA;ICGC;COSMIC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P49790	NUP153	P27361	MAPK3	S614	A618T	618	Missense	distal	4	no	15.797	16.015	EPSD	TCGA;ICGC;COSMIC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P49790	NUP153	P27361	MAPK3	S619	A618T	618	Missense	proximal	-1	no	14.573	14.676	EPSD	TCGA;ICGC;COSMIC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P49790	NUP153	P27361	MAPK3	S633	T632R	632	Missense	proximal	-1	no	15.589	15.578	EPSD	TCGA;ICGC;COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P49790	NUP153	P27361	MAPK3	S633	A631T	631	Missense	proximal	-2	no	15.589	16.954	EPSD	TCGA;ICGC;COSMIC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P49790	NUP153	P27361	MAPK3	S644	I650S	650	Missense	distal	6	no	9.060	9.629	EPSD	TCGA;ICGC;COSMIC	9.358	Gain
CMGC_MAPK_ERK1_MAPK3_ST	P49790	NUP153	P27361	MAPK3	S646	S647F	647	Missense	proximal	1	no	7.756	10.596	EPSD	TCGA;ICGC	9.358	Gain
CMGC_MAPK_ERK1_MAPK3_ST	P49790	NUP153	P27361	MAPK3	T699	N701S	701	Missense	proximal	2	no	15.269	15.286	EPSD	TCGA;ICGC;COSMIC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P49790	NUP153	P27361	MAPK3	T747	P748S	748	Missense	proximal	1	no	13.833	4.779	EPSD	TCGA;ICGC;COSMIC	9.358	Loss
CMGC_MAPK_ERK1_MAPK3_ST	P49790	NUP153	P27361	MAPK3	T747	C745G	745	Missense	proximal	-2	no	13.833	15.232	EPSD	TCGA	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P49790	NUP153	P27361	MAPK3	T996	S1003Y	1003	Missense	distal	7	no	13.637	13.892	EPSD	TCGA;ICGC;COSMIC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P49790	NUP153	P27361	MAPK3	T996	P992Q	992	Missense	distal	-4	no	13.637	13.598	EPSD	TCGA	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P49790	NUP153	P27361	MAPK3	T1032	A1036T	1036	Missense	distal	4	no	14.509	14.727	EPSD	TCGA	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P49790	NUP153	P27361	MAPK3	T1032	G1025S	1025	Missense	distal	-7	no	14.509	14.471	EPSD	TCGA;ICGC;COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P49790	NUP153	P27361	MAPK3	T1032	P1035L	1035	Missense	distal	3	no	14.509	14.472	EPSD	TCGA;ICGC;COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P49790	NUP153	P27361	MAPK3	T1032	S1031A	1031	Missense	proximal	-1	no	14.509	14.375	EPSD	TCGA;ICGC;COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P49790	NUP153	P27361	MAPK3	T1032	G1027D	1027	Missense	distal	-5	no	14.509	14.517	EPSD	TCGA;ICGC;COSMIC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P49790	NUP153	P27361	MAPK3	S1152	S1147L	1147	Missense	distal	-5	no	10.188	10.128	EPSD	TCGA;ICGC;COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P49790	NUP153	P27361	MAPK3	S1152	P1158L	1158	Missense	distal	6	no	10.188	9.961	EPSD	TCGA;ICGC;COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P49790	NUP153	P27361	MAPK3	S1152	T1156A	1156	Missense	distal	4	no	10.188	9.970	EPSD	TCGA;ICGC;COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P49790	NUP153	P27361	MAPK3	S1456	S1457C	1457	Missense	proximal	1	no	9.519	3.264	EPSD	TCGA;ICGC;COSMIC	9.358	Loss
CMGC_MAPK_ERK1_MAPK3_ST	P49790	NUP153	P27361	MAPK3	S1456	F1462L	1462	Missense	distal	6	no	9.519	9.876	EPSD	TCGA;ICGC;COSMIC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P49790	NUP153	P27361	MAPK3	S1457	S1457C	1457	Missense	central	0	yes	9.644	0.000	EPSD	TCGA;ICGC;COSMIC	9.358	Loss
CMGC_MAPK_ERK1_MAPK3_ST	P49790	NUP153	P27361	MAPK3	S1457	F1462L	1462	Missense	distal	5	no	9.644	9.798	EPSD	TCGA;ICGC;COSMIC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P49790	NUP153	P27361	MAPK3	S1461	S1457C	1457	Missense	distal	-4	no	11.219	10.981	EPSD	TCGA;ICGC;COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P49790	NUP153	P27361	MAPK3	S1461	F1462L	1462	Missense	proximal	1	no	11.219	8.394	EPSD	TCGA;ICGC;COSMIC	9.358	Loss
CMGC_MAPK_ERK1_MAPK3_ST	P04049	RAF1	P27361	MAPK3	S25	A20V	20	Missense	distal	-5	no	10.015	10.038	EPSD	TCGA;ICGC;COSMIC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P04049	RAF1	P27361	MAPK3	S25	D19Y	19	Missense	distal	-6	no	10.015	9.823	EPSD	TCGA;ICGC;COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P04049	RAF1	P27361	MAPK3	T260	S257L	257	Missense	distal	-3	no	13.506	13.431	EPSD	TCGA;COSMIC;GDSC;CCLE	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P04049	RAF1	P27361	MAPK3	T260	P261R	261	Missense	proximal	1	no	13.506	4.006	EPSD	TCGA;COSMIC;CCLE	9.358	Loss
CMGC_MAPK_ERK1_MAPK3_ST	P04049	RAF1	P27361	MAPK3	T260	S257W	257	Missense	distal	-3	no	13.506	13.301	EPSD	TCGA;COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P04049	RAF1	P27361	MAPK3	T260	S259F	259	Missense	proximal	-1	no	13.506	13.302	EPSD	TCGA;COSMIC;GDSC;CCLE	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P04049	RAF1	P27361	MAPK3	T260	H264Y	264	Missense	distal	4	no	13.506	13.431	EPSD	TCGA;COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P04049	RAF1	P27361	MAPK3	S283	I281M	281	Missense	proximal	-2	no	9.633	8.717	EPSD	TCGA;COSMIC	9.358	Loss
CMGC_MAPK_ERK1_MAPK3_ST	P04049	RAF1	P27361	MAPK3	S283	E286K	286	Missense	distal	3	no	9.633	9.622	EPSD	TCGA;COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P04049	RAF1	P27361	MAPK3	S289	E286K	286	Missense	distal	-3	no	16.543	16.512	PhosphoSitePlus;EPSD	TCGA;COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P04049	RAF1	P27361	MAPK3	S296	T303A	303	Missense	distal	7	no	17.053	17.281	EPSD;PhosphoSitePlus	TCGA;COSMIC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P04049	RAF1	P27361	MAPK3	S301	T303A	303	Missense	proximal	2	no	15.772	15.745	EPSD;PhosphoSitePlus	TCGA;COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P04049	RAF1	P27361	MAPK3	T310	T303A	303	Missense	distal	-7	no	17.122	17.195	EPSD	TCGA;COSMIC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P04049	RAF1	P27361	MAPK3	S339	R333H	333	Missense	distal	-6	no	10.322	10.318	EPSD	TCGA;COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P04049	RAF1	P27361	MAPK3	S339	S339I	339	Missense	central	0	yes	10.322	0.000	EPSD	TCGA	9.358	Loss
CMGC_MAPK_ERK1_MAPK3_ST	P04049	RAF1	P27361	MAPK3	S359	R354W	354	Missense	distal	-5	no	9.764	9.610	EPSD	TCGA;COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P04049	RAF1	P27361	MAPK3	S359	T353I	353	Missense	distal	-6	no	9.764	9.534	EPSD	TCGA;COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P04049	RAF1	P27361	MAPK3	S359	G366V	366	Missense	distal	7	no	9.764	9.943	EPSD	TCGA;COSMIC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P04049	RAF1	P27361	MAPK3	S359	F360S	360	Missense	proximal	1	no	9.764	6.924	EPSD	TCGA;COSMIC	9.358	Loss
CMGC_MAPK_ERK1_MAPK3_ST	P04049	RAF1	P27361	MAPK3	S604	S605F	605	Missense	proximal	1	no	6.648	9.487	EPSD	TCGA;COSMIC	9.358	Gain
CMGC_MAPK_ERK1_MAPK3_ST	P04049	RAF1	P27361	MAPK3	S642	P646L	646	Missense	distal	4	no	20.254	20.100	EPSD	TCGA;COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q16690	DUSP5	P27361	MAPK3	T321	E314K	314	Missense	distal	-7	no	16.427	16.479	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC;GDSC;CCLE	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q16690	DUSP5	P27361	MAPK3	S346	G340C	340	Missense	distal	-6	no	16.493	15.996	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC;CCLE	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q16690	DUSP5	P27361	MAPK3	S376	E372K	372	Missense	distal	-4	no	18.334	18.275	PhosphoSitePlus;EPSD	TCGA;ICGC;COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q16690	DUSP5	P27361	MAPK3	S376	A381V	381	Missense	distal	5	no	18.334	18.323	PhosphoSitePlus;EPSD	TCGA;ICGC;COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q16690	DUSP5	P27361	MAPK3	S376	T380M	380	Missense	distal	4	no	18.334	18.069	PhosphoSitePlus;EPSD	TCGA;ICGC;COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P15336	ATF2	P27361	MAPK3	T69	P70S	70	Missense	proximal	1	no	14.813	5.760	PhosphoSitePlus;EPSD	TCGA;COSMIC	9.358	Loss
CMGC_MAPK_ERK1_MAPK3_ST	P15336	ATF2	P27361	MAPK3	T71	P70S	70	Missense	proximal	-1	no	14.842	14.836	EPSD;PhosphoSitePlus	TCGA;COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P15336	ATF2	P27361	MAPK3	S90	E93Q	93	Missense	distal	3	no	15.922	15.913	EPSD	TCGA;COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P15336	ATF2	P27361	MAPK3	S90	G83D	83	Missense	distal	-7	no	15.922	15.927	EPSD	TCGA;COSMIC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P15336	ATF2	P27361	MAPK3	S112	T116A	116	Missense	distal	4	no	15.741	15.523	EPSD	TCGA;COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P15336	ATF2	P27361	MAPK3	S112	S112P	112	Missense	central	0	yes	15.741	0.000	EPSD	TCGA;COSMIC	9.358	Loss
CMGC_MAPK_ERK1_MAPK3_ST	P15336	ATF2	P27361	MAPK3	T116	T116A	116	Missense	central	0	yes	14.801	0.000	EPSD	TCGA;COSMIC	9.358	Loss
CMGC_MAPK_ERK1_MAPK3_ST	P15336	ATF2	P27361	MAPK3	T116	S112P	112	Missense	distal	-4	no	14.801	14.774	EPSD	TCGA;COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P15336	ATF2	P27361	MAPK3	S136	D135N	135	Missense	proximal	-1	no	16.279	16.277	EPSD	TCGA	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P15336	ATF2	P27361	MAPK3	S136	S136N	136	Missense	central	0	yes	16.279	0.000	EPSD	TCGA	9.358	Loss
CMGC_MAPK_ERK1_MAPK3_ST	P15336	ATF2	P27361	MAPK3	S143	E148K	148	Missense	distal	5	no	10.251	10.122	EPSD	TCGA;COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P15336	ATF2	P27361	MAPK3	S143	S136N	136	Missense	distal	-7	no	10.251	10.318	EPSD	TCGA	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P15336	ATF2	P27361	MAPK3	S266	G260E	260	Missense	distal	-6	no	17.433	17.479	EPSD	TCGA;COSMIC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P15336	ATF2	P27361	MAPK3	S266	P267S	267	Missense	proximal	1	no	17.433	8.380	EPSD	TCGA;COSMIC	9.358	Loss
CMGC_MAPK_ERK1_MAPK3_ST	P15336	ATF2	P27361	MAPK3	S266	G263C	263	Missense	distal	-3	no	17.433	17.288	EPSD	TCGA;COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P15336	ATF2	P27361	MAPK3	S314	S321F	321	Missense	distal	7	no	9.200	9.691	EPSD	TCGA;COSMIC	9.358	Gain
CMGC_MAPK_ERK1_MAPK3_ST	P15336	ATF2	P27361	MAPK3	T320	S321F	321	Missense	proximal	1	no	8.253	11.092	EPSD	TCGA;COSMIC	9.358	Gain
CMGC_MAPK_ERK1_MAPK3_ST	P15336	ATF2	P27361	MAPK3	T325	P326S	326	Missense	proximal	1	no	14.306	5.252	EPSD	TCGA;COSMIC	9.358	Loss
CMGC_MAPK_ERK1_MAPK3_ST	P15336	ATF2	P27361	MAPK3	T325	S321F	321	Missense	distal	-4	no	14.306	14.117	EPSD	TCGA;COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P15336	ATF2	P27361	MAPK3	S328	P326S	326	Missense	proximal	-2	no	17.676	16.600	EPSD	TCGA;COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P15336	ATF2	P27361	MAPK3	S328	P334A	334	Missense	distal	6	no	17.676	17.280	EPSD	TCGA;COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P15336	ATF2	P27361	MAPK3	S328	S321F	321	Missense	distal	-7	no	17.676	17.895	EPSD	TCGA;COSMIC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P15336	ATF2	P27361	MAPK3	T333	P326S	326	Missense	distal	-7	no	15.687	15.649	EPSD	TCGA;COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P15336	ATF2	P27361	MAPK3	T333	P334A	334	Missense	proximal	1	no	15.687	6.447	EPSD	TCGA;COSMIC	9.358	Loss
CMGC_MAPK_ERK1_MAPK3_ST	P15336	ATF2	P27361	MAPK3	T333	T339A	339	Missense	distal	6	no	15.687	15.316	EPSD	TCGA;COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P15336	ATF2	P27361	MAPK3	S446	Q453H	453	Missense	distal	7	no	17.263	17.201	EPSD	TCGA;COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P15336	ATF2	P27361	MAPK3	S484	D482Y	482	Missense	proximal	-2	no	9.093	9.391	EPSD	TCGA;COSMIC	9.358	Gain
CMGC_MAPK_ERK1_MAPK3_ST	P15336	ATF2	P27361	MAPK3	S497	S500L	500	Missense	distal	3	no	9.495	9.464	EPSD	TCGA;COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P15336	ATF2	P27361	MAPK3	S497	Q499L	499	Missense	proximal	2	no	9.495	9.494	EPSD	TCGA;COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P15336	ATF2	P27361	MAPK3	S497	P502L	502	Missense	distal	5	no	9.495	9.268	EPSD	TCGA;COSMIC	9.358	Loss
CMGC_MAPK_ERK1_MAPK3_ST	P15336	ATF2	P27361	MAPK3	S497	P502T	502	Missense	distal	5	no	9.495	9.403	EPSD	TCGA;COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P15336	ATF2	P27361	MAPK3	S498	S500L	500	Missense	proximal	2	no	12.964	12.940	EPSD	TCGA;COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P15336	ATF2	P27361	MAPK3	S498	Q499L	499	Missense	proximal	1	no	12.964	11.870	EPSD	TCGA;COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P15336	ATF2	P27361	MAPK3	S498	P502L	502	Missense	distal	4	no	12.964	12.809	EPSD	TCGA;COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P15336	ATF2	P27361	MAPK3	S498	P502T	502	Missense	distal	4	no	12.964	12.900	EPSD	TCGA;COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P15336	ATF2	P27361	MAPK3	S500	S500L	500	Missense	central	0	yes	12.203	0.000	EPSD	TCGA;COSMIC	9.358	Loss
CMGC_MAPK_ERK1_MAPK3_ST	P15336	ATF2	P27361	MAPK3	S500	Q499L	499	Missense	proximal	-1	no	12.203	12.195	EPSD	TCGA;COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P15336	ATF2	P27361	MAPK3	S500	P502L	502	Missense	proximal	2	no	12.203	12.182	EPSD	TCGA;COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P15336	ATF2	P27361	MAPK3	S500	P502T	502	Missense	proximal	2	no	12.203	12.194	EPSD	TCGA;COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P49023	PXN	P27361	MAPK3	T29	E27G	27	Missense	proximal	-2	no	16.399	15.929	EPSD	TCGA	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P49023	PXN	P27361	MAPK3	S32	E27G	27	Missense	distal	-5	no	10.893	10.884	EPSD	TCGA	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P49023	PXN	P27361	MAPK3	S119	Q124H	124	Missense	distal	5	no	10.827	10.864	EPSD	TCGA;COSMIC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P49023	PXN	P27361	MAPK3	S130	M134I	134	Missense	distal	4	no	15.799	15.836	EPSD;PhosphoSitePlus	TCGA;COSMIC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P49023	PXN	P27361	MAPK3	S130	E128K	128	Missense	proximal	-2	no	15.799	15.104	EPSD;PhosphoSitePlus	TCGA;COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P49023	PXN	P27361	MAPK3	S130	Q124H	124	Missense	distal	-6	no	15.799	15.785	EPSD;PhosphoSitePlus	TCGA;COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P49023	PXN	P27361	MAPK3	S188	S188N	188	Missense	central	0	yes	16.817	0.000	EPSD	TCGA	9.358	Loss
CMGC_MAPK_ERK1_MAPK3_ST	P49023	PXN	P27361	MAPK3	S226	S227F	227	Missense	proximal	1	no	6.899	9.739	EPSD	TCGA;COSMIC	9.358	Gain
CMGC_MAPK_ERK1_MAPK3_ST	P49023	PXN	P27361	MAPK3	S230	S227F	227	Missense	distal	-3	no	14.654	14.512	EPSD	TCGA;COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P49023	PXN	P27361	MAPK3	S230	V237A	237	Missense	distal	7	no	14.654	14.682	EPSD	TCGA	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P49023	PXN	P27361	MAPK3	S244	V248I	248	Missense	distal	4	no	12.682	12.564	EPSD	TCGA;COSMIC;CCLE	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P49023	PXN	P27361	MAPK3	S244	R247H	247	Missense	distal	3	no	12.682	12.690	EPSD	TCGA;COSMIC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P49023	PXN	P27361	MAPK3	S244	V237A	237	Missense	distal	-7	no	12.682	12.683	EPSD	TCGA	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P42224	STAT1	P27361	MAPK3	S485	E480K	480	Missense	distal	-5	no	10.553	10.541	EPSD	TCGA;ICGC;COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P42224	STAT1	P27361	MAPK3	T489	R494Q	494	Missense	distal	5	no	11.420	11.418	EPSD	TCGA;ICGC;COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P42224	STAT1	P27361	MAPK3	S532	P538L	538	Missense	distal	6	no	18.108	17.881	EPSD	TCGA;ICGC;COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P42224	STAT1	P27361	MAPK3	S532	D534N	534	Missense	proximal	2	no	18.108	18.102	EPSD	TCGA;ICGC;COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P42224	STAT1	P27361	MAPK3	S532	P538S	538	Missense	distal	6	no	18.108	18.238	EPSD	TCGA;ICGC;COSMIC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P42224	STAT1	P27361	MAPK3	S532	A531T	531	Missense	proximal	-1	no	18.108	18.211	EPSD	TCGA;ICGC;COSMIC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P42224	STAT1	P27361	MAPK3	S606	R608W	608	Missense	proximal	2	no	10.573	10.513	EPSD	TCGA;ICGC;COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P42224	STAT1	P27361	MAPK3	S606	E605D	605	Missense	proximal	-1	no	10.573	10.551	EPSD	TCGA;ICGC;COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P42224	STAT1	P27361	MAPK3	S606	E609K	609	Missense	distal	3	no	10.573	10.562	EPSD	TCGA;ICGC;COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P42224	STAT1	P27361	MAPK3	S606	A611T	611	Missense	distal	5	no	10.573	10.693	EPSD	TCGA	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P42224	STAT1	P27361	MAPK3	S727	D732H	732	Missense	distal	5	no	21.132	21.066	PhosphoSitePlus	TCGA;ICGC;COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P42224	STAT1	P27361	MAPK3	S727	E733K	733	Missense	distal	6	no	21.132	21.056	PhosphoSitePlus	TCGA;ICGC;COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P14618	PKM	P27361	MAPK3	T25	R32C	32	Missense	distal	7	no	9.773	10.215	EPSD	TCGA;ICGC;COSMIC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P14618	PKM	P27361	MAPK3	T25	R32H	32	Missense	distal	7	no	9.773	9.740	EPSD	TCGA;ICGC;COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P14618	PKM	P27361	MAPK3	S37	R43P	43	Missense	distal	6	no	16.418	16.530	PhosphoSitePlus	TCGA;ICGC;COSMIC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P14618	PKM	P27361	MAPK3	S37	R32C	32	Missense	distal	-5	no	16.418	16.302	PhosphoSitePlus	TCGA;ICGC;COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P14618	PKM	P27361	MAPK3	S37	R32H	32	Missense	distal	-5	no	16.418	16.428	PhosphoSitePlus	TCGA;ICGC;COSMIC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P14618	PKM	P27361	MAPK3	T143	L144P	144	Missense	proximal	1	no	4.699	13.738	EPSD	TCGA;ICGC;COSMIC	9.358	Gain
CMGC_MAPK_ERK1_MAPK3_ST	P14618	PKM	P27361	MAPK3	S243	A242V	242	Missense	proximal	-1	no	10.490	10.540	EPSD	TCGA;COSMIC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P14618	PKM	P27361	MAPK3	S420	V417L	417	Missense	distal	-3	no	11.313	11.310	EPSD	TCGA;ICGC;COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P56270	MAZ	P27361	MAPK3	S323	M322I	322	Missense	proximal	-1	no	10.768	10.792	EPSD	TCGA;ICGC;COSMIC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P56270	MAZ	P27361	MAPK3	S323	S323N	323	Missense	central	0	yes	10.768	0.000	EPSD	TCGA;COSMIC	9.358	Loss
CMGC_MAPK_ERK1_MAPK3_ST	P56270	MAZ	P27361	MAPK3	S402	S403W	403	Missense	proximal	1	no	8.595	9.745	EPSD	TCGA;ICGC;COSMIC	9.358	Gain
CMGC_MAPK_ERK1_MAPK3_ST	Q9BUB5	MKNK1	P27361	MAPK3	S221	L218W	218	Missense	distal	-3	no	12.818	12.689	EPSD	TCGA;COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q9BUB5	MKNK1	P27361	MAPK3	T255	E261K	261	Missense	distal	6	no	17.074	16.998	EPSD	TCGA;COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q9BUB5	MKNK1	P27361	MAPK3	T255	S259C	259	Missense	distal	4	no	17.074	16.571	EPSD	TCGA;COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q9BUB5	MKNK1	P27361	MAPK3	T255	A260T	260	Missense	distal	5	no	17.074	17.194	EPSD	TCGA	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q9BUB5	MKNK1	P27361	MAPK3	T385	P379L	379	Missense	distal	-6	no	14.907	14.660	PhosphoSitePlus	TCGA;ICGC;COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q9BUB5	MKNK1	P27361	MAPK3	T385	A378T	378	Missense	distal	-7	no	14.907	14.834	PhosphoSitePlus	TCGA;ICGC;COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q9BUB5	MKNK1	P27361	MAPK3	S437	P439S	439	Missense	proximal	2	no	17.038	17.040	EPSD	TCGA;COSMIC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q9BUB5	MKNK1	P27361	MAPK3	S437	R443C	443	Missense	distal	6	no	17.038	16.413	EPSD	TCGA;COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q9BUB5	MKNK1	P27361	MAPK3	S437	S437F	437	Missense	central	0	yes	17.038	0.000	EPSD	TCGA;COSMIC	9.358	Loss
CMGC_MAPK_ERK1_MAPK3_ST	Q9BUB5	MKNK1	P27361	MAPK3	S460	D458G	458	Missense	proximal	-2	no	19.168	18.659	EPSD	TCGA	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q9UJY1	HSPB8	P27361	MAPK3	S24	S24C	24	Missense	central	0	yes	19.917	0.000	PhosphoSitePlus;EPSD	TCGA;ICGC;COSMIC	9.358	Loss
CMGC_MAPK_ERK1_MAPK3_ST	Q9UJY1	HSPB8	P27361	MAPK3	S24	R29H	29	Missense	distal	5	no	19.917	19.953	PhosphoSitePlus;EPSD	TCGA;ICGC;COSMIC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q9UJY1	HSPB8	P27361	MAPK3	S27	S24C	24	Missense	distal	-3	no	11.443	11.265	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q9UJY1	HSPB8	P27361	MAPK3	S27	R29H	29	Missense	proximal	2	no	11.443	11.440	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q9UJY1	HSPB8	P27361	MAPK3	S28	R29H	29	Missense	proximal	1	no	8.840	10.585	EPSD	TCGA;ICGC;COSMIC	9.358	Gain
CMGC_MAPK_ERK1_MAPK3_ST	Q9UJY1	HSPB8	P27361	MAPK3	T87	E84K	84	Missense	distal	-3	no	14.689	14.657	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC;GDSC;CCLE	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q9UJY1	HSPB8	P27361	MAPK3	T87	P88H	88	Missense	proximal	1	no	14.689	6.933	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	9.358	Loss
CMGC_MAPK_ERK1_MAPK3_ST	Q9UJY1	HSPB8	P27361	MAPK3	T87	E84Q	84	Missense	distal	-3	no	14.689	14.663	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q9UJY1	HSPB8	P27361	MAPK3	T87	E94K	94	Missense	distal	7	no	14.689	14.759	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC;GDSC;CCLE	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q9UJY1	HSPB8	P27361	MAPK3	S104	L110F	110	Missense	distal	6	no	11.361	11.004	EPSD	TCGA;ICGC;COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q05682	CALD1	P27361	MAPK3	S480	V478G	478	Missense	proximal	-2	no	10.179	9.717	EPSD	TCGA;COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q05682	CALD1	P27361	MAPK3	S480	K485N	485	Missense	distal	5	no	10.179	10.208	EPSD	TCGA;COSMIC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q05682	CALD1	P27361	MAPK3	T638	S643Y	643	Missense	distal	5	no	13.188	12.972	EPSD	TCGA;COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q05682	CALD1	P27361	MAPK3	T638	S643F	643	Missense	distal	5	no	13.188	12.763	EPSD	TCGA;COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q05682	CALD1	P27361	MAPK3	T638	K631N	631	Missense	distal	-7	no	13.188	13.171	EPSD	TCGA;COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q05682	CALD1	P27361	MAPK3	T638	F634C	634	Missense	distal	-4	no	13.188	13.139	EPSD	TCGA;COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q05682	CALD1	P27361	MAPK3	S642	S643Y	643	Missense	proximal	1	no	7.662	9.666	EPSD	TCGA;COSMIC	9.358	Gain
CMGC_MAPK_ERK1_MAPK3_ST	Q05682	CALD1	P27361	MAPK3	S642	S643F	643	Missense	proximal	1	no	7.662	10.501	EPSD	TCGA;COSMIC	9.358	Gain
CMGC_MAPK_ERK1_MAPK3_ST	Q05682	CALD1	P27361	MAPK3	S700	A698T	698	Missense	proximal	-2	no	9.340	10.705	EPSD	TCGA;COSMIC	9.358	Gain
CMGC_MAPK_ERK1_MAPK3_ST	Q05682	CALD1	P27361	MAPK3	S700	K696T	696	Missense	distal	-4	no	9.340	9.366	EPSD	TCGA;COSMIC	9.358	Gain
CMGC_MAPK_ERK1_MAPK3_ST	Q05682	CALD1	P27361	MAPK3	S759	S765Y	765	Missense	distal	6	no	13.838	13.456	PhosphoSitePlus;EPSD	TCGA	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P53004	BLVRA	P27361	MAPK3	S211	E217K	217	Missense	distal	6	no	14.049	13.973	EPSD	TCGA;ICGC;COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P53004	BLVRA	P27361	MAPK3	S230	S235C	235	Missense	distal	5	no	12.213	11.690	PhosphoSitePlus	TCGA;ICGC;COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P53004	BLVRA	P27361	MAPK3	S230	K234N	234	Missense	distal	4	no	12.213	12.205	PhosphoSitePlus	TCGA	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P53004	BLVRA	P27361	MAPK3	S230	S237C	237	Missense	distal	7	no	12.213	12.825	PhosphoSitePlus	TCGA;ICGC;COSMIC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P53004	BLVRA	P27361	MAPK3	S230	G236W	236	Missense	distal	6	no	12.213	11.381	PhosphoSitePlus	TCGA;ICGC;COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P53004	BLVRA	P27361	MAPK3	S230	N226H	226	Missense	distal	-4	no	12.213	12.211	PhosphoSitePlus	TCGA;ICGC;COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P53004	BLVRA	P27361	MAPK3	S230	H232N	232	Missense	proximal	2	no	12.213	12.211	PhosphoSitePlus	TCGA;ICGC;COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P38936	CDKN1A	P27361	MAPK3	T57	G61V	61	Missense	distal	4	no	13.226	13.164	EPSD	TCGA;ICGC;COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P38936	CDKN1A	P27361	MAPK3	T57	E56K	56	Missense	proximal	-1	no	13.226	13.196	EPSD	TCGA;ICGC;COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P38936	CDKN1A	P27361	MAPK3	T57	P58L	58	Missense	proximal	1	no	13.226	4.188	EPSD	TCGA;ICGC;COSMIC	9.358	Loss
CMGC_MAPK_ERK1_MAPK3_ST	P38936	CDKN1A	P27361	MAPK3	S98	R94W	94	Missense	distal	-4	no	15.652	15.444	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P38936	CDKN1A	P27361	MAPK3	S98	R93S	93	Missense	distal	-5	no	15.652	15.697	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P38936	CDKN1A	P27361	MAPK3	S98	R94P	94	Missense	distal	-4	no	15.652	15.701	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P38936	CDKN1A	P27361	MAPK3	S98	P95S	95	Missense	distal	-3	no	15.652	15.643	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P38936	CDKN1A	P27361	MAPK3	S130	D136H	136	Missense	distal	6	no	16.417	16.371	PhosphoSitePlus;EPSD	TCGA;ICGC;COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P38936	CDKN1A	P27361	MAPK3	S130	G132C	132	Missense	proximal	2	no	16.417	16.373	PhosphoSitePlus;EPSD	TCGA;ICGC;COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P38936	CDKN1A	P27361	MAPK3	S130	E128K	128	Missense	proximal	-2	no	16.417	15.723	PhosphoSitePlus;EPSD	TCGA;ICGC;COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P38936	CDKN1A	P27361	MAPK3	S130	G135A	135	Missense	distal	5	no	16.417	16.227	PhosphoSitePlus;EPSD	TCGA	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P38936	CDKN1A	P27361	MAPK3	S137	D136H	136	Missense	proximal	-1	no	10.411	10.419	EPSD	TCGA;ICGC;COSMIC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P38936	CDKN1A	P27361	MAPK3	S137	G132C	132	Missense	distal	-5	no	10.411	10.293	EPSD	TCGA;ICGC;COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P38936	CDKN1A	P27361	MAPK3	S137	G135A	135	Missense	proximal	-2	no	10.411	10.177	EPSD	TCGA	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P38936	CDKN1A	P27361	MAPK3	S137	R142W	142	Missense	distal	5	no	10.411	9.943	EPSD	TCGA;ICGC;COSMIC;GDSC;CCLE	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P38936	CDKN1A	P27361	MAPK3	T145	D149H	149	Missense	distal	4	no	9.904	9.884	EPSD	TCGA;ICGC;COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P38936	CDKN1A	P27361	MAPK3	T145	R142W	142	Missense	distal	-3	no	9.904	9.737	EPSD	TCGA;ICGC;COSMIC;GDSC;CCLE	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q92934	BAD	P27361	MAPK3	S25	E19D	19	Missense	distal	-6	no	18.920	18.875	EPSD	TCGA;ICGC;COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q92934	BAD	P27361	MAPK3	S25	S25N	25	Missense	central	0	yes	18.920	0.000	EPSD	TCGA	9.358	Loss
CMGC_MAPK_ERK1_MAPK3_ST	Q92934	BAD	P27361	MAPK3	S57	G62E	62	Missense	distal	5	no	9.816	9.857	EPSD	TCGA;ICGC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q92934	BAD	P27361	MAPK3	S75	S71I	71	Missense	distal	-4	no	11.801	11.641	PhosphoSitePlus	TCGA;ICGC;COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q92934	BAD	P27361	MAPK3	S124	M117I	117	Missense	distal	-7	no	10.499	10.485	EPSD	TCGA;ICGC;COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q92934	BAD	P27361	MAPK3	S124	R131H	131	Missense	distal	7	no	10.499	10.466	EPSD	TCGA;ICGC;COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q92934	BAD	P27361	MAPK3	T139	G136D	136	Missense	distal	-3	no	9.743	9.752	EPSD	TCGA;ICGC;COSMIC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q92934	BAD	P27361	MAPK3	T139	S134I	134	Missense	distal	-5	no	9.743	9.648	EPSD	TCGA	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q92934	BAD	P27361	MAPK3	S163	S164F	164	Missense	proximal	1	no	7.943	10.783	EPSD	TCGA;ICGC;COSMIC;GDSC;CCLE	9.358	Gain
CMGC_MAPK_ERK1_MAPK3_ST	Q9H8Y8	GORASP2	P27361	MAPK3	S26	V22A	22	Missense	distal	-4	no	19.020	19.040	EPSD	TCGA;ICGC;COSMIC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q9H8Y8	GORASP2	P27361	MAPK3	S26	G28E	28	Missense	proximal	2	no	19.020	19.028	EPSD	TCGA;ICGC;COSMIC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q9H8Y8	GORASP2	P27361	MAPK3	S26	S26F	26	Missense	central	0	yes	19.020	0.000	EPSD	TCGA;ICGC;COSMIC	9.358	Loss
CMGC_MAPK_ERK1_MAPK3_ST	Q9H8Y8	GORASP2	P27361	MAPK3	S245	N240I	240	Missense	distal	-5	no	16.426	16.372	EPSD	TCGA;ICGC;COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q9H8Y8	GORASP2	P27361	MAPK3	T264	S260Y	260	Missense	distal	-4	no	16.378	16.275	EPSD	TCGA;ICGC;COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q9H8Y8	GORASP2	P27361	MAPK3	S432	V425I	425	Missense	distal	-7	no	11.605	11.647	EPSD	TCGA;ICGC;COSMIC;GDSC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P19793	RXRA	P27361	MAPK3	S17	Q14K	14	Missense	distal	-3	no	9.954	9.949	EPSD	TCGA;ICGC;COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P19793	RXRA	P27361	MAPK3	S17	Q14L	14	Missense	distal	-3	no	9.954	9.924	EPSD	TCGA;ICGC;COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P19793	RXRA	P27361	MAPK3	S21	S27C	27	Missense	distal	6	no	18.489	17.622	EPSD	TCGA;ICGC;COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P19793	RXRA	P27361	MAPK3	S21	Q14K	14	Missense	distal	-7	no	18.489	18.491	EPSD	TCGA;ICGC;COSMIC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P19793	RXRA	P27361	MAPK3	S21	Q14L	14	Missense	distal	-7	no	18.489	18.552	EPSD	TCGA;ICGC;COSMIC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P19793	RXRA	P27361	MAPK3	S49	L47V	47	Missense	proximal	-2	no	16.919	16.649	EPSD	TCGA;ICGC;COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P19793	RXRA	P27361	MAPK3	S49	S43F	43	Missense	distal	-6	no	16.919	16.451	EPSD	TCGA;ICGC;COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P19793	RXRA	P27361	MAPK3	S66	V67F	67	Missense	proximal	1	no	8.445	11.654	EPSD	TCGA;ICGC;COSMIC	9.358	Gain
CMGC_MAPK_ERK1_MAPK3_ST	P19793	RXRA	P27361	MAPK3	T82	S78L	78	Missense	distal	-4	no	16.644	16.504	EPSD	TCGA;ICGC;COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P19793	RXRA	P27361	MAPK3	T82	M77V	77	Missense	distal	-5	no	16.644	16.687	EPSD	TCGA;ICGC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P19793	RXRA	P27361	MAPK3	S225	P231L	231	Missense	distal	6	no	9.861	9.635	EPSD	TCGA;ICGC;COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P19793	RXRA	P27361	MAPK3	S225	A226T	226	Missense	proximal	1	no	9.861	10.224	EPSD	TCGA;ICGC;COSMIC;GDSC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P19793	RXRA	P27361	MAPK3	S260	V265I	265	Missense	distal	5	no	19.444	19.318	PhosphoSitePlus	TCGA	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P19793	RXRA	P27361	MAPK3	S260	G255W	255	Missense	distal	-5	no	19.444	19.288	PhosphoSitePlus	TCGA;ICGC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P78536	ADAM17	P27361	MAPK3	S180	P181L	181	Missense	proximal	1	no	16.765	7.727	EPSD	TCGA;ICGC;COSMIC	9.358	Loss
CMGC_MAPK_ERK1_MAPK3_ST	P78536	ADAM17	P27361	MAPK3	S180	S176L	176	Missense	distal	-4	no	16.765	16.625	EPSD	TCGA;ICGC;COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P78536	ADAM17	P27361	MAPK3	S180	R177C	177	Missense	distal	-3	no	16.765	16.625	EPSD	TCGA;ICGC;COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P78536	ADAM17	P27361	MAPK3	T801	T796M	796	Missense	distal	-5	no	9.682	9.580	EPSD	TCGA;ICGC;COSMIC;CCLE	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P78536	ADAM17	P27361	MAPK3	T801	R802K	802	Missense	proximal	1	no	9.682	2.030	EPSD	TCGA;ICGC;COSMIC	9.358	Loss
CMGC_MAPK_ERK1_MAPK3_ST	P78536	ADAM17	P27361	MAPK3	T801	A806V	806	Missense	distal	5	no	9.682	9.671	EPSD	TCGA;ICGC;COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P78536	ADAM17	P27361	MAPK3	S808	R813C	813	Missense	distal	5	no	11.225	10.846	EPSD	TCGA;ICGC;COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P78536	ADAM17	P27361	MAPK3	S808	R802K	802	Missense	distal	-6	no	11.225	11.227	EPSD	TCGA;ICGC;COSMIC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P78536	ADAM17	P27361	MAPK3	S808	A806V	806	Missense	proximal	-2	no	11.225	11.922	EPSD	TCGA;ICGC;COSMIC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q8WX93	PALLD	P27361	MAPK3	S9	E8Q	8	Missense	proximal	-1	no	9.510	9.455	EPSD	TCGA;ICGC;COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q8WX93	PALLD	P27361	MAPK3	S15	E8Q	8	Missense	distal	-7	no	10.249	10.299	EPSD	TCGA;ICGC;COSMIC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q8WX93	PALLD	P27361	MAPK3	S15	K22N	22	Missense	distal	7	no	10.249	10.240	EPSD	TCGA;ICGC;COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q8WX93	PALLD	P27361	MAPK3	S71	S71F	71	Missense	central	0	yes	15.044	0.000	EPSD	TCGA;ICGC;COSMIC	9.358	Loss
CMGC_MAPK_ERK1_MAPK3_ST	Q8WX93	PALLD	P27361	MAPK3	S71	P72H	72	Missense	proximal	1	no	15.044	7.289	EPSD	TCGA;COSMIC	9.358	Loss
CMGC_MAPK_ERK1_MAPK3_ST	Q8WX93	PALLD	P27361	MAPK3	T100	A106E	106	Missense	distal	6	no	14.893	15.287	EPSD	TCGA;ICGC;COSMIC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q8WX93	PALLD	P27361	MAPK3	T100	P101H	101	Missense	proximal	1	no	14.893	7.137	EPSD	TCGA;COSMIC	9.358	Loss
CMGC_MAPK_ERK1_MAPK3_ST	Q8WX93	PALLD	P27361	MAPK3	T100	Q95H	95	Missense	distal	-5	no	14.893	14.910	EPSD	TCGA;COSMIC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q8WX93	PALLD	P27361	MAPK3	S125	S132N	132	Missense	distal	7	no	14.755	14.921	EPSD	TCGA;COSMIC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q8WX93	PALLD	P27361	MAPK3	S125	P126L	126	Missense	proximal	1	no	14.755	5.717	EPSD	TCGA;COSMIC	9.358	Loss
CMGC_MAPK_ERK1_MAPK3_ST	Q8WX93	PALLD	P27361	MAPK3	S132	S136N	136	Missense	distal	4	no	9.644	9.497	EPSD	TCGA	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q8WX93	PALLD	P27361	MAPK3	S132	S132N	132	Missense	central	0	yes	9.644	0.000	EPSD	TCGA;COSMIC	9.358	Loss
CMGC_MAPK_ERK1_MAPK3_ST	Q8WX93	PALLD	P27361	MAPK3	S132	P126L	126	Missense	distal	-6	no	9.644	9.396	EPSD	TCGA;COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q8WX93	PALLD	P27361	MAPK3	T147	R143C	143	Missense	distal	-4	no	13.536	13.375	EPSD	TCGA;COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q8WX93	PALLD	P27361	MAPK3	T147	G144R	144	Missense	distal	-3	no	13.536	13.531	EPSD	TCGA;COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q8WX93	PALLD	P27361	MAPK3	T147	R143S	143	Missense	distal	-4	no	13.536	13.613	EPSD	TCGA;COSMIC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q8WX93	PALLD	P27361	MAPK3	T147	P148L	148	Missense	proximal	1	no	13.536	4.498	EPSD	TCGA;COSMIC	9.358	Loss
CMGC_MAPK_ERK1_MAPK3_ST	Q8WX93	PALLD	P27361	MAPK3	T147	S149G	149	Missense	proximal	2	no	13.536	13.519	EPSD	TCGA;COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q8WX93	PALLD	P27361	MAPK3	S192	R189T	189	Missense	distal	-3	no	13.583	13.591	EPSD	TCGA;COSMIC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q8WX93	PALLD	P27361	MAPK3	S199	S202R	202	Missense	distal	3	no	15.780	15.758	EPSD	TCGA;COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q8WX93	PALLD	P27361	MAPK3	S206	P207S	207	Missense	proximal	1	no	15.447	6.394	EPSD	TCGA;COSMIC	9.358	Loss
CMGC_MAPK_ERK1_MAPK3_ST	Q8WX93	PALLD	P27361	MAPK3	S206	S202R	202	Missense	distal	-4	no	15.447	15.370	EPSD	TCGA;COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q8WX93	PALLD	P27361	MAPK3	S222	G228E	228	Missense	distal	6	no	17.496	17.597	EPSD	TCGA;COSMIC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q8WX93	PALLD	P27361	MAPK3	S236	A239V	239	Missense	distal	3	no	13.902	13.909	EPSD	TCGA;COSMIC;GDSC;CCLE	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q8WX93	PALLD	P27361	MAPK3	S401	G398R	398	Missense	distal	-3	no	16.434	16.429	EPSD	TCGA;COSMIC;CCLE	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q8WX93	PALLD	P27361	MAPK3	S423	L428I	428	Missense	distal	5	no	15.594	15.472	EPSD	TCGA;COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q8WX93	PALLD	P27361	MAPK3	S423	R430Q	430	Missense	distal	7	no	15.594	15.624	EPSD	TCGA;COSMIC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q8WX93	PALLD	P27361	MAPK3	S484	S484F	484	Missense	central	0	yes	15.389	0.000	EPSD	TCGA;COSMIC	9.358	Loss
CMGC_MAPK_ERK1_MAPK3_ST	Q8WX93	PALLD	P27361	MAPK3	T635	L640R	640	Missense	distal	5	no	14.894	15.022	EPSD	TCGA;ICGC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q8WX93	PALLD	P27361	MAPK3	T635	A637S	637	Missense	proximal	2	no	14.894	14.933	EPSD	TCGA;ICGC;COSMIC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q8WX93	PALLD	P27361	MAPK3	S641	L640R	640	Missense	proximal	-1	no	16.563	16.610	EPSD	TCGA;ICGC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q8WX93	PALLD	P27361	MAPK3	S641	A637S	637	Missense	distal	-4	no	16.563	16.695	EPSD	TCGA;ICGC;COSMIC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q8WX93	PALLD	P27361	MAPK3	S641	P648L	648	Missense	distal	7	no	16.563	16.756	EPSD	TCGA;ICGC;COSMIC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q9UBN7	HDAC6	P27361	MAPK3	S28	S31L	31	Missense	distal	3	no	9.646	9.614	EPSD	TCGA;ICGC;COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q9UBN7	HDAC6	P27361	MAPK3	S28	R33Q	33	Missense	distal	5	no	9.646	9.644	EPSD	TCGA;ICGC;COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q9UBN7	HDAC6	P27361	MAPK3	S412	P408H	408	Missense	distal	-4	no	14.743	14.707	EPSD	TCGA;COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q9UBN7	HDAC6	P27361	MAPK3	T527	R529L	529	Missense	proximal	2	no	14.189	14.178	EPSD	TCGA;COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q9UBN7	HDAC6	P27361	MAPK3	S886	V882D	882	Missense	distal	-4	no	9.709	9.825	EPSD	TCGA;COSMIC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q9UBN7	HDAC6	P27361	MAPK3	S886	M879I	879	Missense	distal	-7	no	9.709	9.695	EPSD	TCGA	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q9UBN7	HDAC6	P27361	MAPK3	S886	K881T	881	Missense	distal	-5	no	9.709	9.739	EPSD	TCGA	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q9UBN7	HDAC6	P27361	MAPK3	T1021	G1014R	1014	Missense	distal	-7	no	15.977	16.022	EPSD	TCGA;COSMIC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q9UBN7	HDAC6	P27361	MAPK3	T1021	E1017K	1017	Missense	distal	-4	no	15.977	15.917	EPSD	TCGA;COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q9UBN7	HDAC6	P27361	MAPK3	T1031	S1035L	1035	Missense	distal	4	no	16.435	16.231	EPSD;PhosphoSitePlus	TCGA;COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q9UBN7	HDAC6	P27361	MAPK3	T1031	Q1030H	1030	Missense	proximal	-1	no	16.435	16.476	EPSD;PhosphoSitePlus	TCGA	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q9UBN7	HDAC6	P27361	MAPK3	S1035	S1035L	1035	Missense	central	0	yes	17.446	0.000	PhosphoSitePlus;EPSD	TCGA;COSMIC	9.358	Loss
CMGC_MAPK_ERK1_MAPK3_ST	Q9UBN7	HDAC6	P27361	MAPK3	S1035	Q1030H	1030	Missense	distal	-5	no	17.446	17.463	PhosphoSitePlus;EPSD	TCGA	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q9UBN7	HDAC6	P27361	MAPK3	T1041	S1035L	1035	Missense	distal	-6	no	14.772	14.441	EPSD	TCGA;COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q9UBN7	HDAC6	P27361	MAPK3	T1041	Q1043H	1043	Missense	proximal	2	no	14.772	14.779	EPSD	TCGA;COSMIC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q9UBN7	HDAC6	P27361	MAPK3	T1048	Q1043H	1043	Missense	distal	-5	no	9.982	9.999	EPSD	TCGA;COSMIC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q9UBN7	HDAC6	P27361	MAPK3	S1062	E1061K	1061	Missense	proximal	-1	no	9.401	9.371	EPSD	TCGA;COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q9UBN7	HDAC6	P27361	MAPK3	S1062	G1064E	1064	Missense	proximal	2	no	9.401	9.409	EPSD	TCGA;COSMIC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q9UBN7	HDAC6	P27361	MAPK3	S1068	E1061K	1061	Missense	distal	-7	no	10.297	10.349	EPSD	TCGA;COSMIC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q9UBN7	HDAC6	P27361	MAPK3	S1068	G1064E	1064	Missense	distal	-4	no	10.297	10.312	EPSD	TCGA;COSMIC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q04637	EIF4G1	P27361	MAPK3	S15	A22T	22	Missense	distal	7	no	15.941	15.713	EPSD	TCGA;ICGC;COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q04637	EIF4G1	P27361	MAPK3	T43	S45Y	45	Missense	proximal	2	no	12.683	12.661	EPSD	TCGA;COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q04637	EIF4G1	P27361	MAPK3	S134	G139S	139	Missense	distal	5	no	16.905	16.970	EPSD	TCGA	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q04637	EIF4G1	P27361	MAPK3	S253	S260I	260	Missense	distal	7	no	15.425	15.823	EPSD	TCGA	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q04637	EIF4G1	P27361	MAPK3	S257	S260I	260	Missense	distal	3	no	10.015	9.964	EPSD	TCGA	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q04637	EIF4G1	P27361	MAPK3	S261	S267L	267	Missense	distal	6	no	18.445	18.088	EPSD	TCGA;COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q04637	EIF4G1	P27361	MAPK3	S261	S260I	260	Missense	proximal	-1	no	18.445	18.314	EPSD	TCGA	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q04637	EIF4G1	P27361	MAPK3	S263	S267L	267	Missense	distal	4	no	16.762	16.559	EPSD	TCGA;COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q04637	EIF4G1	P27361	MAPK3	S263	S260I	260	Missense	distal	-3	no	16.762	16.651	EPSD	TCGA	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q04637	EIF4G1	P27361	MAPK3	T265	S267L	267	Missense	proximal	2	no	17.256	17.233	EPSD	TCGA;COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q04637	EIF4G1	P27361	MAPK3	T265	S260I	260	Missense	distal	-5	no	17.256	17.162	EPSD	TCGA	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q04637	EIF4G1	P27361	MAPK3	S267	S267L	267	Missense	central	0	yes	17.935	0.000	EPSD	TCGA;COSMIC	9.358	Loss
CMGC_MAPK_ERK1_MAPK3_ST	Q04637	EIF4G1	P27361	MAPK3	S267	S260I	260	Missense	distal	-7	no	17.935	18.127	EPSD	TCGA	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q04637	EIF4G1	P27361	MAPK3	S269	S267L	267	Missense	proximal	-2	no	18.952	18.644	EPSD	TCGA;COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q04637	EIF4G1	P27361	MAPK3	T1179	R1173Q	1173	Missense	distal	-6	no	14.976	14.986	EPSD	TCGA	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P50616	TOB1	P27361	MAPK3	S147	S147L	147	Missense	central	0	yes	10.821	0.000	EPSD	TCGA;ICGC;COSMIC	9.358	Loss
CMGC_MAPK_ERK1_MAPK3_ST	P50616	TOB1	P27361	MAPK3	S147	I142T	142	Missense	distal	-5	no	10.821	10.899	EPSD	TCGA;ICGC;COSMIC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P50616	TOB1	P27361	MAPK3	S152	S147L	147	Missense	distal	-5	no	16.831	16.772	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P50616	TOB1	P27361	MAPK3	S154	S147L	147	Missense	distal	-7	no	17.394	17.539	PhosphoSitePlus;EPSD	TCGA;ICGC;COSMIC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P50616	TOB1	P27361	MAPK3	S164	S164N	164	Missense	central	0	yes	16.627	0.000	EPSD;PhosphoSitePlus	TCGA	9.358	Loss
CMGC_MAPK_ERK1_MAPK3_ST	P50616	TOB1	P27361	MAPK3	S164	M168V	168	Missense	distal	4	no	16.627	16.782	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P50616	TOB1	P27361	MAPK3	T166	S164N	164	Missense	proximal	-2	no	9.578	8.634	EPSD	TCGA	9.358	Loss
CMGC_MAPK_ERK1_MAPK3_ST	P50616	TOB1	P27361	MAPK3	T166	M168V	168	Missense	proximal	2	no	9.578	9.597	EPSD	TCGA;ICGC;COSMIC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P50616	TOB1	P27361	MAPK3	S205	S205F	205	Missense	central	0	yes	16.223	0.000	EPSD	TCGA;ICGC;COSMIC	9.358	Loss
CMGC_MAPK_ERK1_MAPK3_ST	P50616	TOB1	P27361	MAPK3	S205	N208S	208	Missense	distal	3	no	16.223	16.243	EPSD	TCGA;ICGC;COSMIC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P50616	TOB1	P27361	MAPK3	S205	G210R	210	Missense	distal	5	no	16.223	16.144	EPSD	TCGA;ICGC;COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P50616	TOB1	P27361	MAPK3	S205	L209F	209	Missense	distal	4	no	16.223	16.012	EPSD	TCGA;ICGC;COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P50616	TOB1	P27361	MAPK3	S205	V201A	201	Missense	distal	-4	no	16.223	16.243	EPSD	TCGA;ICGC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P50616	TOB1	P27361	MAPK3	S205	R203H	203	Missense	proximal	-2	no	16.223	16.395	EPSD	TCGA;ICGC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P50616	TOB1	P27361	MAPK3	S205	K200N	200	Missense	distal	-5	no	16.223	16.228	EPSD	TCGA;ICGC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P50616	TOB1	P27361	MAPK3	S268	S265T	265	Missense	distal	-3	no	16.658	16.628	EPSD	TCGA;ICGC;COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P49815	TSC2	P27361	MAPK3	T23	S30Y	30	Missense	distal	7	no	18.214	18.469	EPSD	TCGA;ICGC;COSMIC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P49815	TSC2	P27361	MAPK3	T23	K16N	16	Missense	distal	-7	no	18.214	18.198	EPSD	TCGA;ICGC;COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P49815	TSC2	P27361	MAPK3	S30	E32Q	32	Missense	proximal	2	no	10.019	10.005	EPSD	TCGA;ICGC;COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P49815	TSC2	P27361	MAPK3	S30	S30Y	30	Missense	central	0	yes	10.019	0.000	EPSD	TCGA;ICGC;COSMIC	9.358	Loss
CMGC_MAPK_ERK1_MAPK3_ST	P49815	TSC2	P27361	MAPK3	S540	R537H	537	Missense	distal	-3	no	16.225	16.231	EPSD	TCGA;ICGC;COSMIC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P49815	TSC2	P27361	MAPK3	S664	G668W	668	Missense	distal	4	no	18.206	17.753	PhosphoSitePlus	TCGA;ICGC;COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P49815	TSC2	P27361	MAPK3	S775	P768L	768	Missense	distal	-7	no	10.332	10.439	EPSD	TCGA;ICGC;COSMIC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P49815	TSC2	P27361	MAPK3	S923	R917L	917	Missense	distal	-6	no	11.019	10.847	EPSD	TCGA	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P49815	TSC2	P27361	MAPK3	S923	R917W	917	Missense	distal	-6	no	11.019	10.496	EPSD	TCGA;ICGC;COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P49815	TSC2	P27361	MAPK3	S923	R917Q	917	Missense	distal	-6	no	11.019	11.028	EPSD	TCGA	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P49815	TSC2	P27361	MAPK3	T927	R934S	934	Missense	distal	7	no	15.895	15.726	EPSD	TCGA;ICGC;COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P49815	TSC2	P27361	MAPK3	S1002	D1004N	1004	Missense	proximal	2	no	9.362	9.356	EPSD	TCGA;COSMIC	9.358	Loss
CMGC_MAPK_ERK1_MAPK3_ST	P49815	TSC2	P27361	MAPK3	S1002	G1001V	1001	Missense	proximal	-1	no	9.362	9.344	EPSD	TCGA;COSMIC	9.358	Loss
CMGC_MAPK_ERK1_MAPK3_ST	P49815	TSC2	P27361	MAPK3	S1045	L1051I	1051	Missense	distal	6	no	14.972	14.759	EPSD	TCGA	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P49815	TSC2	P27361	MAPK3	S1045	E1049K	1049	Missense	distal	4	no	14.972	14.934	EPSD	TCGA;COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P49815	TSC2	P27361	MAPK3	S1045	S1045F	1045	Missense	central	0	yes	14.972	0.000	EPSD	TCGA	9.358	Loss
CMGC_MAPK_ERK1_MAPK3_ST	P49815	TSC2	P27361	MAPK3	S1045	S1045Y	1045	Missense	central	0	yes	14.972	0.000	EPSD	TCGA;COSMIC	9.358	Loss
CMGC_MAPK_ERK1_MAPK3_ST	P49815	TSC2	P27361	MAPK3	S1097	P1098L	1098	Missense	proximal	1	no	16.656	7.618	EPSD	TCGA;COSMIC	9.358	Loss
CMGC_MAPK_ERK1_MAPK3_ST	P49815	TSC2	P27361	MAPK3	S1097	G1091S	1091	Missense	distal	-6	no	16.656	16.718	EPSD	TCGA;COSMIC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P49815	TSC2	P27361	MAPK3	S1387	S1386I	1386	Missense	proximal	-1	no	9.585	9.454	EPSD	TCGA;COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P49815	TSC2	P27361	MAPK3	S1388	S1386I	1386	Missense	proximal	-2	no	16.488	15.725	EPSD	TCGA;COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P49815	TSC2	P27361	MAPK3	S1448	S1449C	1449	Missense	proximal	1	no	9.785	3.531	EPSD	TCGA;COSMIC	9.358	Loss
CMGC_MAPK_ERK1_MAPK3_ST	P49815	TSC2	P27361	MAPK3	S1448	R1451C	1451	Missense	distal	3	no	9.785	9.722	EPSD	TCGA;COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P49815	TSC2	P27361	MAPK3	S1449	S1449C	1449	Missense	central	0	yes	17.069	0.000	EPSD	TCGA;COSMIC	9.358	Loss
CMGC_MAPK_ERK1_MAPK3_ST	P49815	TSC2	P27361	MAPK3	S1449	R1451C	1451	Missense	proximal	2	no	17.069	17.020	EPSD	TCGA;COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P49815	TSC2	P27361	MAPK3	S1452	S1449C	1449	Missense	distal	-3	no	17.941	17.764	EPSD	TCGA;COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P49815	TSC2	P27361	MAPK3	S1452	R1457Q	1457	Missense	distal	5	no	17.941	17.940	EPSD	TCGA;COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P49815	TSC2	P27361	MAPK3	S1452	R1451C	1451	Missense	proximal	-1	no	17.941	17.756	EPSD	TCGA;COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P49815	TSC2	P27361	MAPK3	S1464	S1466L	1466	Missense	proximal	2	no	9.946	9.923	EPSD	TCGA	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P49815	TSC2	P27361	MAPK3	S1464	R1457Q	1457	Missense	distal	-7	no	9.946	9.945	EPSD	TCGA;COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P49815	TSC2	P27361	MAPK3	S1539	D1541N	1541	Missense	proximal	2	no	9.681	9.675	EPSD	TCGA;COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P49815	TSC2	P27361	MAPK3	S1798	E1805K	1805	Missense	distal	7	no	9.592	9.663	EPSD	TCGA;COSMIC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P49815	TSC2	P27361	MAPK3	S1798	S1798C	1798	Missense	central	0	yes	9.592	0.000	EPSD	TCGA;COSMIC	9.358	Loss
CMGC_MAPK_ERK1_MAPK3_ST	P49815	TSC2	P27361	MAPK3	S1798	S1798F	1798	Missense	central	0	yes	9.592	0.000	EPSD	TCGA;COSMIC	9.358	Loss
CMGC_MAPK_ERK1_MAPK3_ST	P10415	BCL2	P27361	MAPK3	T56	A61T	61	Missense	distal	5	no	15.980	16.099	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC;CCLE	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q9NQ66	PLCB1	P27361	MAPK3	T39	R44S	44	Missense	distal	5	no	15.226	15.369	EPSD	TCGA;ICGC;COSMIC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q9NQ66	PLCB1	P27361	MAPK3	T39	D33N	33	Missense	distal	-6	no	15.226	15.164	EPSD	TCGA;ICGC;COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q9NQ66	PLCB1	P27361	MAPK3	S387	A394S	394	Missense	distal	7	no	9.702	9.356	EPSD	TCGA;ICGC;COSMIC	9.358	Loss
CMGC_MAPK_ERK1_MAPK3_ST	Q9NQ66	PLCB1	P27361	MAPK3	S387	T383A	383	Missense	distal	-4	no	9.702	9.629	EPSD	TCGA;ICGC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q9NQ66	PLCB1	P27361	MAPK3	S410	S417F	417	Missense	distal	7	no	9.264	9.754	EPSD	TCGA;ICGC;COSMIC	9.358	Gain
CMGC_MAPK_ERK1_MAPK3_ST	Q9NQ66	PLCB1	P27361	MAPK3	S417	S410L	410	Missense	distal	-7	no	16.108	16.253	EPSD	TCGA;ICGC;COSMIC;GDSC;CCLE	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q9NQ66	PLCB1	P27361	MAPK3	S417	S417F	417	Missense	central	0	yes	16.108	0.000	EPSD	TCGA;ICGC;COSMIC	9.358	Loss
CMGC_MAPK_ERK1_MAPK3_ST	Q9NQ66	PLCB1	P27361	MAPK3	S417	E412A	412	Missense	distal	-5	no	16.108	16.044	EPSD	TCGA;ICGC;COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q9NQ66	PLCB1	P27361	MAPK3	S417	V415M	415	Missense	proximal	-2	no	16.108	15.008	EPSD	TCGA;ICGC;COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q9NQ66	PLCB1	P27361	MAPK3	S454	P455L	455	Missense	proximal	1	no	15.399	6.361	EPSD	TCGA;ICGC;COSMIC	9.358	Loss
CMGC_MAPK_ERK1_MAPK3_ST	Q9NQ66	PLCB1	P27361	MAPK3	S454	S454R	454	Missense	central	0	yes	15.399	0.000	EPSD	TCGA;ICGC;COSMIC	9.358	Loss
CMGC_MAPK_ERK1_MAPK3_ST	Q9NQ66	PLCB1	P27361	MAPK3	S454	D457N	457	Missense	distal	3	no	15.399	15.388	EPSD	TCGA;ICGC;COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q9NQ66	PLCB1	P27361	MAPK3	S500	S501Y	501	Missense	proximal	1	no	7.521	9.526	EPSD	TCGA;ICGC;COSMIC	9.358	Gain
CMGC_MAPK_ERK1_MAPK3_ST	Q9NQ66	PLCB1	P27361	MAPK3	S501	G505A	505	Missense	distal	4	no	17.376	17.206	EPSD	TCGA;COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q9NQ66	PLCB1	P27361	MAPK3	S501	S495R	495	Missense	distal	-6	no	17.376	17.216	EPSD	TCGA;ICGC;COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q9NQ66	PLCB1	P27361	MAPK3	S501	S501Y	501	Missense	central	0	yes	17.376	0.000	EPSD	TCGA;ICGC;COSMIC	9.358	Loss
CMGC_MAPK_ERK1_MAPK3_ST	Q9NQ66	PLCB1	P27361	MAPK3	S501	M496I	496	Missense	distal	-5	no	17.376	17.400	EPSD	TCGA;ICGC;COSMIC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q9NQ66	PLCB1	P27361	MAPK3	S501	E498K	498	Missense	distal	-3	no	17.376	17.345	EPSD	TCGA;ICGC;COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q9NQ66	PLCB1	P27361	MAPK3	S582	V584M	584	Missense	proximal	2	no	17.743	17.725	EPSD	TCGA;ICGC;COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q9NQ66	PLCB1	P27361	MAPK3	S582	F586Y	586	Missense	distal	4	no	17.743	17.941	EPSD	TCGA;ICGC;COSMIC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q9NQ66	PLCB1	P27361	MAPK3	T871	H866N	866	Missense	distal	-5	no	15.473	15.469	EPSD	TCGA;ICGC;COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q9NQ66	PLCB1	P27361	MAPK3	T871	V864L	864	Missense	distal	-7	no	15.473	15.468	EPSD	TCGA;ICGC;COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q9NQ66	PLCB1	P27361	MAPK3	T871	H866Y	866	Missense	distal	-5	no	15.473	15.445	EPSD	TCGA;ICGC;COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q9NQ66	PLCB1	P27361	MAPK3	S876	S881N	881	Missense	distal	5	no	9.885	9.763	EPSD	TCGA;ICGC;COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q9NQ66	PLCB1	P27361	MAPK3	S982	T989M	989	Missense	distal	7	no	17.827	18.159	PhosphoSitePlus	TCGA;ICGC;COSMIC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q9NQ66	PLCB1	P27361	MAPK3	S982	G986C	986	Missense	distal	4	no	17.827	17.484	PhosphoSitePlus	TCGA;ICGC;COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q9NQ66	PLCB1	P27361	MAPK3	S982	P983H	983	Missense	proximal	1	no	17.827	10.071	PhosphoSitePlus	TCGA;ICGC;COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q9NQ66	PLCB1	P27361	MAPK3	S982	H985Y	985	Missense	distal	3	no	17.827	17.811	PhosphoSitePlus	TCGA;ICGC;COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q9NQ66	PLCB1	P27361	MAPK3	S982	S981N	981	Missense	proximal	-1	no	17.827	17.778	PhosphoSitePlus	TCGA;ICGC;COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q9NQ66	PLCB1	P27361	MAPK3	T1197	V1193G	1193	Missense	distal	-4	no	20.818	20.931	EPSD	TCGA;ICGC;COSMIC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q9NQ66	PLCB1	P27361	MAPK3	T1197	G1191V	1191	Missense	distal	-6	no	20.818	20.551	EPSD	TCGA;ICGC;COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q9NQ66	PLCB1	P27361	MAPK3	T1197	P1190T	1190	Missense	distal	-7	no	20.818	20.857	EPSD	TCGA;ICGC;COSMIC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q9NQ66	PLCB1	P27361	MAPK3	T1197	P1190H	1190	Missense	distal	-7	no	20.818	20.852	EPSD	TCGA;ICGC;COSMIC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q9NQ66	PLCB1	P27361	MAPK3	S1199	V1193G	1193	Missense	distal	-6	no	10.765	11.032	EPSD	TCGA;ICGC;COSMIC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q9NQ66	PLCB1	P27361	MAPK3	S1200	V1193G	1193	Missense	distal	-7	no	12.511	12.399	EPSD	TCGA;ICGC;COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q9NQ66	PLCB1	P27361	MAPK3	S1200	I1207V	1207	Missense	distal	7	no	12.511	12.430	EPSD	TCGA;ICGC;COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q13950	RUNX2	P27361	MAPK3	S24	P29T	29	Missense	distal	5	no	10.701	10.608	EPSD;PhosphoSitePlus	TCGA;COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q13950	RUNX2	P27361	MAPK3	S24	D20N	20	Missense	distal	-4	no	10.701	10.675	EPSD;PhosphoSitePlus	TCGA;COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q13950	RUNX2	P27361	MAPK3	S24	P29S	29	Missense	distal	5	no	10.701	10.744	EPSD;PhosphoSitePlus	TCGA;COSMIC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q13950	RUNX2	P27361	MAPK3	S28	P29T	29	Missense	proximal	1	no	16.754	7.876	EPSD;PhosphoSitePlus	TCGA;COSMIC	9.358	Loss
CMGC_MAPK_ERK1_MAPK3_ST	Q13950	RUNX2	P27361	MAPK3	S28	P29S	29	Missense	proximal	1	no	16.754	7.700	EPSD;PhosphoSitePlus	TCGA;COSMIC	9.358	Loss
CMGC_MAPK_ERK1_MAPK3_ST	Q13950	RUNX2	P27361	MAPK3	S294	P296S	296	Missense	proximal	2	no	14.564	14.566	EPSD;PhosphoSitePlus	TCGA;COSMIC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q13950	RUNX2	P27361	MAPK3	S298	P296S	296	Missense	proximal	-2	no	9.480	8.404	EPSD	TCGA;COSMIC	9.358	Loss
CMGC_MAPK_ERK1_MAPK3_ST	Q13950	RUNX2	P27361	MAPK3	S302	Q309E	309	Missense	distal	7	no	10.485	10.390	EPSD	TCGA;COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q13950	RUNX2	P27361	MAPK3	S302	P296S	296	Missense	distal	-6	no	10.485	10.569	EPSD	TCGA;COSMIC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q13950	RUNX2	P27361	MAPK3	S305	S312F	312	Missense	distal	7	no	10.376	10.866	EPSD	TCGA;COSMIC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q13950	RUNX2	P27361	MAPK3	S305	Q309E	309	Missense	distal	4	no	10.376	10.467	EPSD	TCGA;COSMIC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q13950	RUNX2	P27361	MAPK3	S305	T311M	311	Missense	distal	6	no	10.376	9.881	EPSD	TCGA;COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q13950	RUNX2	P27361	MAPK3	S305	M310T	310	Missense	distal	5	no	10.376	10.631	EPSD	TCGA;COSMIC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q13950	RUNX2	P27361	MAPK3	S312	S312F	312	Missense	central	0	yes	13.545	0.000	PhosphoSitePlus;EPSD	TCGA;COSMIC	9.358	Loss
CMGC_MAPK_ERK1_MAPK3_ST	Q13950	RUNX2	P27361	MAPK3	S312	Q309E	309	Missense	distal	-3	no	13.545	13.571	PhosphoSitePlus;EPSD	TCGA;COSMIC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q13950	RUNX2	P27361	MAPK3	S312	T318S	318	Missense	distal	6	no	13.545	13.700	PhosphoSitePlus;EPSD	TCGA;COSMIC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q13950	RUNX2	P27361	MAPK3	S312	T311M	311	Missense	proximal	-1	no	13.545	13.420	PhosphoSitePlus;EPSD	TCGA;COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q13950	RUNX2	P27361	MAPK3	S312	M310T	310	Missense	proximal	-2	no	13.545	15.314	PhosphoSitePlus;EPSD	TCGA;COSMIC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q13950	RUNX2	P27361	MAPK3	T319	S312F	312	Missense	distal	-7	no	14.702	14.921	EPSD	TCGA;COSMIC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q13950	RUNX2	P27361	MAPK3	T319	R325Q	325	Missense	distal	6	no	14.702	14.633	EPSD	TCGA;COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q13950	RUNX2	P27361	MAPK3	T319	T318S	318	Missense	proximal	-1	no	14.702	14.732	EPSD	TCGA;COSMIC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q13950	RUNX2	P27361	MAPK3	T319	P320L	320	Missense	proximal	1	no	14.702	5.664	EPSD	TCGA;COSMIC	9.358	Loss
CMGC_MAPK_ERK1_MAPK3_ST	Q13950	RUNX2	P27361	MAPK3	S322	T318S	318	Missense	distal	-4	no	10.246	10.304	EPSD	TCGA;COSMIC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q13950	RUNX2	P27361	MAPK3	S322	P320L	320	Missense	proximal	-2	no	10.246	8.861	EPSD	TCGA;COSMIC	9.358	Loss
CMGC_MAPK_ERK1_MAPK3_ST	Q13950	RUNX2	P27361	MAPK3	S340	V335A	335	Missense	distal	-5	no	10.197	10.174	EPSD;PhosphoSitePlus	TCGA	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q13950	RUNX2	P27361	MAPK3	S340	R337M	337	Missense	distal	-3	no	10.197	10.108	EPSD;PhosphoSitePlus	TCGA;COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q13950	RUNX2	P27361	MAPK3	S340	R338H	338	Missense	proximal	-2	no	10.197	10.369	EPSD;PhosphoSitePlus	TCGA;COSMIC;CCLE	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q13950	RUNX2	P27361	MAPK3	S340	D341Y	341	Missense	proximal	1	no	10.197	11.750	EPSD;PhosphoSitePlus	TCGA;COSMIC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q13950	RUNX2	P27361	MAPK3	S465	P460S	460	Missense	distal	-5	no	15.290	15.295	EPSD	TCGA;COSMIC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q13950	RUNX2	P27361	MAPK3	S465	P466S	466	Missense	proximal	1	no	15.290	6.237	EPSD	TCGA;COSMIC	9.358	Loss
CMGC_MAPK_ERK1_MAPK3_ST	Q13950	RUNX2	P27361	MAPK3	S499	V506F	506	Missense	distal	7	no	11.318	11.491	EPSD	TCGA;COSMIC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q13950	RUNX2	P27361	MAPK3	S499	S503Y	503	Missense	distal	4	no	11.318	11.102	EPSD	TCGA;COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q13950	RUNX2	P27361	MAPK3	S501	V506F	506	Missense	distal	5	no	11.548	11.390	EPSD	TCGA;COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q13950	RUNX2	P27361	MAPK3	S501	S503Y	503	Missense	proximal	2	no	11.548	11.527	EPSD	TCGA;COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q13950	RUNX2	P27361	MAPK3	S502	V506F	506	Missense	distal	4	no	12.013	11.822	EPSD	TCGA;COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q13950	RUNX2	P27361	MAPK3	S502	S503Y	503	Missense	proximal	1	no	12.013	14.018	EPSD	TCGA;COSMIC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q13950	RUNX2	P27361	MAPK3	S503	V506F	506	Missense	distal	3	no	20.559	20.532	EPSD;PhosphoSitePlus	TCGA;COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q13950	RUNX2	P27361	MAPK3	S503	S503Y	503	Missense	central	0	yes	20.559	0.000	EPSD;PhosphoSitePlus	TCGA;COSMIC	9.358	Loss
CMGC_MAPK_ERK1_MAPK3_ST	Q13950	RUNX2	P27361	MAPK3	T505	V506F	506	Missense	proximal	1	no	8.064	11.273	EPSD	TCGA;COSMIC	9.358	Gain
CMGC_MAPK_ERK1_MAPK3_ST	P17655	CAPN2	P27361	MAPK3	S50	P49T	49	Missense	proximal	-1	no	11.625	11.589	PhosphoSitePlus	TCGA;ICGC;COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P17655	CAPN2	P27361	MAPK3	S50	A57T	57	Missense	distal	7	no	11.625	11.397	PhosphoSitePlus	TCGA;ICGC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P17655	CAPN2	P27361	MAPK3	T380	N384S	384	Missense	distal	4	no	10.301	10.447	EPSD	TCGA;ICGC;COSMIC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P17655	CAPN2	P27361	MAPK3	T380	G373R	373	Missense	distal	-7	no	10.301	10.346	EPSD	TCGA	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P17655	CAPN2	P27361	MAPK3	T380	R375S	375	Missense	distal	-5	no	10.301	10.346	EPSD	TCGA;ICGC;COSMIC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P17655	CAPN2	P27361	MAPK3	T406	D400N	400	Missense	distal	-6	no	9.557	9.495	EPSD	TCGA;ICGC;COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P17655	CAPN2	P27361	MAPK3	T406	Q413E	413	Missense	distal	7	no	9.557	9.462	EPSD	TCGA;ICGC;COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P17655	CAPN2	P27361	MAPK3	T406	V409M	409	Missense	distal	3	no	9.557	9.532	EPSD	TCGA;ICGC;COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P17655	CAPN2	P27361	MAPK3	T464	V471A	471	Missense	distal	7	no	9.340	9.368	EPSD	TCGA;ICGC;COSMIC	9.358	Gain
CMGC_MAPK_ERK1_MAPK3_ST	P28324	ELK4	P27361	MAPK3	T135	S136F	136	Missense	proximal	1	no	6.882	9.722	EPSD	TCGA;ICGC;COSMIC	9.358	Gain
CMGC_MAPK_ERK1_MAPK3_ST	P28324	ELK4	P27361	MAPK3	S180	E177D	177	Missense	distal	-3	no	17.767	17.764	EPSD	TCGA;ICGC;COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P28324	ELK4	P27361	MAPK3	S180	S180F	180	Missense	central	0	yes	17.767	0.000	EPSD	TCGA;ICGC;COSMIC	9.358	Loss
CMGC_MAPK_ERK1_MAPK3_ST	P28324	ELK4	P27361	MAPK3	T185	K190R	190	Missense	distal	5	no	14.448	14.456	EPSD	TCGA;ICGC;COSMIC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P28324	ELK4	P27361	MAPK3	T185	S180F	180	Missense	distal	-5	no	14.448	14.313	EPSD	TCGA;ICGC;COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P28324	ELK4	P27361	MAPK3	T194	K190R	190	Missense	distal	-4	no	16.000	16.007	EPSD	TCGA;ICGC;COSMIC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P28324	ELK4	P27361	MAPK3	S215	S217C	217	Missense	proximal	2	no	16.641	16.579	EPSD	TCGA;ICGC;COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P28324	ELK4	P27361	MAPK3	S215	E219Q	219	Missense	distal	4	no	16.641	16.550	EPSD	TCGA;ICGC;COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P28324	ELK4	P27361	MAPK3	S215	I214F	214	Missense	proximal	-1	no	16.641	16.568	EPSD	TCGA;ICGC;COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P28324	ELK4	P27361	MAPK3	S215	G211D	211	Missense	distal	-4	no	16.641	16.644	EPSD	TCGA;ICGC;COSMIC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P28324	ELK4	P27361	MAPK3	S218	E219Q	219	Missense	proximal	1	no	9.220	10.524	EPSD	TCGA;ICGC;COSMIC	9.358	Gain
CMGC_MAPK_ERK1_MAPK3_ST	P28324	ELK4	P27361	MAPK3	S387	R390K	390	Missense	distal	3	no	17.434	17.432	PhosphoSitePlus;EPSD	TCGA;ICGC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P28324	ELK4	P27361	MAPK3	T420	D416G	416	Missense	distal	-4	no	18.224	18.221	EPSD	TCGA;ICGC;COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P28324	ELK4	P27361	MAPK3	T420	P418L	418	Missense	proximal	-2	no	18.224	16.840	EPSD	TCGA;ICGC;COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P28324	ELK4	P27361	MAPK3	S425	P418L	418	Missense	distal	-7	no	22.250	22.357	EPSD	TCGA;ICGC;COSMIC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	O75030	MITF	P27361	MAPK3	T23	S29G	29	Missense	distal	6	no	11.407	11.174	EPSD	TCGA;ICGC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	O75030	MITF	P27361	MAPK3	T23	H18R	18	Missense	distal	-5	no	11.407	11.397	EPSD	TCGA;ICGC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	O75030	MITF	P27361	MAPK3	S175	A177T	177	Missense	proximal	2	no	10.252	10.280	EPSD	TCGA;ICGC;COSMIC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	O75030	MITF	P27361	MAPK3	S175	V172L	172	Missense	distal	-3	no	10.252	10.249	EPSD	TCGA;ICGC;COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	O75030	MITF	P27361	MAPK3	S175	P178L	178	Missense	distal	3	no	10.252	10.215	EPSD	TCGA;ICGC;COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	O75030	MITF	P27361	MAPK3	S175	P171L	171	Missense	distal	-4	no	10.252	10.139	EPSD	TCGA;ICGC;COSMIC;CCLE	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	O75030	MITF	P27361	MAPK3	S180	A177T	177	Missense	distal	-3	no	20.188	20.249	EPSD	TCGA;ICGC;COSMIC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	O75030	MITF	P27361	MAPK3	S180	T186M	186	Missense	distal	6	no	20.188	19.693	EPSD	TCGA;ICGC;COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	O75030	MITF	P27361	MAPK3	S180	P178L	178	Missense	proximal	-2	no	20.188	18.803	EPSD	TCGA;ICGC;COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	O75030	MITF	P27361	MAPK3	S216	R217Q	217	Missense	proximal	1	no	8.475	10.032	EPSD	TCGA;ICGC;COSMIC	9.358	Gain
CMGC_MAPK_ERK1_MAPK3_ST	P03372	ESR1	P27361	MAPK3	S106	P113S	113	Missense	distal	7	no	16.212	16.134	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P03372	ESR1	P27361	MAPK3	S118	P113S	113	Missense	distal	-5	no	15.977	15.982	PhosphoSitePlus;EPSD	TCGA;ICGC;COSMIC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P03372	ESR1	P27361	MAPK3	S294	W292R	292	Missense	proximal	-2	no	14.592	16.488	EPSD	TCGA;ICGC;COSMIC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P03372	ESR1	P27361	MAPK3	S294	I298M	298	Missense	distal	4	no	14.592	14.554	EPSD	TCGA;ICGC;COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P03372	ESR1	P27361	MAPK3	S294	L291I	291	Missense	distal	-3	no	14.592	14.556	EPSD	TCGA;ICGC;COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P03372	ESR1	P27361	MAPK3	S573	S575L	575	Missense	proximal	2	no	9.490	9.466	EPSD	TCGA;ICGC;COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P03372	ESR1	P27361	MAPK3	S575	S575L	575	Missense	central	0	yes	11.699	0.000	EPSD	TCGA;ICGC;COSMIC	9.358	Loss
CMGC_MAPK_ERK1_MAPK3_ST	P03372	ESR1	P27361	MAPK3	S575	K581T	581	Missense	distal	6	no	11.699	11.752	EPSD	TCGA;ICGC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P03372	ESR1	P27361	MAPK3	S576	S575L	575	Missense	proximal	-1	no	13.096	13.007	EPSD	TCGA;ICGC;COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P03372	ESR1	P27361	MAPK3	S576	K581T	581	Missense	distal	5	no	13.096	13.112	EPSD	TCGA;ICGC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P03372	ESR1	P27361	MAPK3	S578	T585M	585	Missense	distal	7	no	10.031	10.363	EPSD	TCGA;ICGC;COSMIC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P03372	ESR1	P27361	MAPK3	S578	S575L	575	Missense	distal	-3	no	10.031	9.955	EPSD	TCGA;ICGC;COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P03372	ESR1	P27361	MAPK3	S578	K581T	581	Missense	distal	3	no	10.031	10.041	EPSD	TCGA;ICGC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q13614	MTMR2	P27361	MAPK3	S26	S33L	33	Missense	distal	7	no	10.236	10.506	EPSD	TCGA;ICGC;COSMIC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q13614	MTMR2	P27361	MAPK3	S27	S33L	33	Missense	distal	6	no	10.494	10.137	EPSD	TCGA;ICGC;COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q13614	MTMR2	P27361	MAPK3	S27	E34D	34	Missense	distal	7	no	10.494	10.496	EPSD	TCGA;ICGC;COSMIC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q13614	MTMR2	P27361	MAPK3	S29	S33L	33	Missense	distal	4	no	10.079	9.876	EPSD	TCGA;ICGC;COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q13614	MTMR2	P27361	MAPK3	S29	E34D	34	Missense	distal	5	no	10.079	10.061	EPSD	TCGA;ICGC;COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q13614	MTMR2	P27361	MAPK3	S58	L64P	64	Missense	distal	6	no	14.679	14.905	PhosphoSitePlus	TCGA;ICGC;COSMIC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q13614	MTMR2	P27361	MAPK3	S260	R266H	266	Missense	distal	6	no	9.502	9.520	EPSD	TCGA;COSMIC;CCLE	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q13614	MTMR2	P27361	MAPK3	S558	V563I	563	Missense	distal	5	no	10.270	10.143	EPSD	TCGA;COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q13614	MTMR2	P27361	MAPK3	S622	Q615H	615	Missense	distal	-7	no	10.697	10.687	EPSD	TCGA;COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q13614	MTMR2	P27361	MAPK3	T637	V642I	642	Missense	distal	5	no	16.641	16.515	EPSD	TCGA;COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P41212	ETV6	P27361	MAPK3	T4	K11N	11	Missense	distal	7	no	13.152	13.143	EPSD	TCGA;ICGC;COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P41212	ETV6	P27361	MAPK3	T4	A6V	6	Missense	proximal	2	no	13.152	13.165	EPSD	TCGA;ICGC;COSMIC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P41212	ETV6	P27361	MAPK3	S16	K11N	11	Missense	distal	-5	no	10.814	10.820	EPSD	TCGA;ICGC;COSMIC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P41212	ETV6	P27361	MAPK3	S16	S22C	22	Missense	distal	6	no	10.814	9.947	EPSD	TCGA;ICGC;COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P41212	ETV6	P27361	MAPK3	S16	P19H	19	Missense	distal	3	no	10.814	10.795	EPSD	TCGA;ICGC;COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P41212	ETV6	P27361	MAPK3	S16	R14Q	14	Missense	proximal	-2	no	10.814	10.450	EPSD	TCGA;ICGC;COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P41212	ETV6	P27361	MAPK3	T18	K11N	11	Missense	distal	-7	no	18.242	18.225	EPSD	TCGA;ICGC;COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P41212	ETV6	P27361	MAPK3	T18	S22C	22	Missense	distal	4	no	18.242	17.738	EPSD	TCGA;ICGC;COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P41212	ETV6	P27361	MAPK3	T18	P19H	19	Missense	proximal	1	no	18.242	10.486	EPSD	TCGA;ICGC;COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P41212	ETV6	P27361	MAPK3	T18	R14Q	14	Missense	distal	-4	no	18.242	18.252	EPSD	TCGA;ICGC;COSMIC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P41212	ETV6	P27361	MAPK3	S22	S22C	22	Missense	central	0	yes	18.707	0.000	EPSD	TCGA;ICGC;COSMIC	9.358	Loss
CMGC_MAPK_ERK1_MAPK3_ST	P41212	ETV6	P27361	MAPK3	S22	P19H	19	Missense	distal	-3	no	18.707	18.667	EPSD	TCGA;ICGC;COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P41212	ETV6	P27361	MAPK3	S22	A28T	28	Missense	distal	6	no	18.707	19.078	EPSD	TCGA;ICGC;COSMIC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P41212	ETV6	P27361	MAPK3	S26	S22C	22	Missense	distal	-4	no	12.337	12.099	EPSD	TCGA;ICGC;COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P41212	ETV6	P27361	MAPK3	S26	P19H	19	Missense	distal	-7	no	12.337	12.371	EPSD	TCGA;ICGC;COSMIC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P41212	ETV6	P27361	MAPK3	S26	A28T	28	Missense	proximal	2	no	12.337	12.364	EPSD	TCGA;ICGC;COSMIC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P41212	ETV6	P27361	MAPK3	S29	S22C	22	Missense	distal	-7	no	9.503	9.772	EPSD	TCGA;ICGC;COSMIC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P41212	ETV6	P27361	MAPK3	S29	A28T	28	Missense	proximal	-1	no	9.503	9.606	EPSD	TCGA;ICGC;COSMIC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P41212	ETV6	P27361	MAPK3	T31	A28T	28	Missense	distal	-3	no	15.403	15.465	EPSD	TCGA;ICGC;COSMIC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P41212	ETV6	P27361	MAPK3	T86	G91D	91	Missense	distal	5	no	10.112	10.135	EPSD	TCGA;ICGC;COSMIC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P41212	ETV6	P27361	MAPK3	T86	D83N	83	Missense	distal	-3	no	10.112	10.090	EPSD	TCGA;ICGC;COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P41212	ETV6	P27361	MAPK3	T86	L79S	79	Missense	distal	-7	no	10.112	9.967	EPSD	TCGA;ICGC;COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P41212	ETV6	P27361	MAPK3	T86	E88K	88	Missense	proximal	2	no	10.112	10.104	EPSD	TCGA;ICGC;COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P41212	ETV6	P27361	MAPK3	S131	L129I	129	Missense	proximal	-2	no	15.976	15.522	EPSD	TCGA;ICGC;COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P41212	ETV6	P27361	MAPK3	S131	G137E	137	Missense	distal	6	no	15.976	16.077	EPSD	TCGA;ICGC;COSMIC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P41212	ETV6	P27361	MAPK3	S131	L129P	129	Missense	proximal	-2	no	15.976	17.360	EPSD	TCGA;ICGC;COSMIC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P41212	ETV6	P27361	MAPK3	S184	R191Q	191	Missense	distal	7	no	16.650	16.680	EPSD	TCGA;ICGC;COSMIC;GDSC;CCLE	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P41212	ETV6	P27361	MAPK3	S184	R181L	181	Missense	distal	-3	no	16.650	16.612	EPSD	TCGA;ICGC;COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P41212	ETV6	P27361	MAPK3	S184	R181C	181	Missense	distal	-3	no	16.650	16.510	EPSD	TCGA;ICGC;COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P41212	ETV6	P27361	MAPK3	S184	R183M	183	Missense	proximal	-1	no	16.650	16.536	EPSD	TCGA;ICGC;COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P41212	ETV6	P27361	MAPK3	S193	R191Q	191	Missense	proximal	-2	no	16.703	16.339	EPSD	TCGA;ICGC;COSMIC;GDSC;CCLE	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P41212	ETV6	P27361	MAPK3	S193	P194S	194	Missense	proximal	1	no	16.703	7.649	EPSD	TCGA;ICGC;COSMIC;GDSC;CCLE	9.358	Loss
CMGC_MAPK_ERK1_MAPK3_ST	P41212	ETV6	P27361	MAPK3	S193	R199Q	199	Missense	distal	6	no	16.703	16.634	EPSD	TCGA;ICGC;COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P41212	ETV6	P27361	MAPK3	S203	R202L	202	Missense	proximal	-1	no	17.076	17.029	EPSD	TCGA;ICGC;COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P41212	ETV6	P27361	MAPK3	S203	P204L	204	Missense	proximal	1	no	17.076	8.038	EPSD	TCGA;ICGC;COSMIC	9.358	Loss
CMGC_MAPK_ERK1_MAPK3_ST	P41212	ETV6	P27361	MAPK3	S203	R210C	210	Missense	distal	7	no	17.076	17.519	EPSD	TCGA;ICGC;COSMIC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P41212	ETV6	P27361	MAPK3	S203	R199Q	199	Missense	distal	-4	no	17.076	17.086	EPSD	TCGA;ICGC;COSMIC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P41212	ETV6	P27361	MAPK3	S213	P214L	214	Missense	proximal	1	no	15.938	6.900	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC;CCLE	9.358	Loss
CMGC_MAPK_ERK1_MAPK3_ST	P41212	ETV6	P27361	MAPK3	S213	R217T	217	Missense	distal	4	no	15.938	15.972	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P41212	ETV6	P27361	MAPK3	S213	R210C	210	Missense	distal	-3	no	15.938	15.798	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P41212	ETV6	P27361	MAPK3	S213	R211H	211	Missense	proximal	-2	no	15.938	16.111	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P41212	ETV6	P27361	MAPK3	S213	Q219R	219	Missense	distal	6	no	15.938	16.008	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P41212	ETV6	P27361	MAPK3	S236	E241K	241	Missense	distal	5	no	10.493	10.365	EPSD	TCGA;ICGC;COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P41212	ETV6	P27361	MAPK3	S236	S238Y	238	Missense	proximal	2	no	10.493	10.472	EPSD	TCGA;ICGC;COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P41212	ETV6	P27361	MAPK3	S238	E241K	241	Missense	distal	3	no	17.742	17.731	EPSD	TCGA;ICGC;COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P41212	ETV6	P27361	MAPK3	S238	S238Y	238	Missense	central	0	yes	17.742	0.000	EPSD	TCGA;ICGC;COSMIC	9.358	Loss
CMGC_MAPK_ERK1_MAPK3_ST	P41212	ETV6	P27361	MAPK3	S248	E241K	241	Missense	distal	-7	no	9.596	9.647	EPSD	TCGA;ICGC;COSMIC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P41212	ETV6	P27361	MAPK3	S248	P253L	253	Missense	distal	5	no	9.596	9.368	EPSD	TCGA;ICGC;COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P41212	ETV6	P27361	MAPK3	S257	P253L	253	Missense	distal	-4	no	18.675	18.562	PhosphoSitePlus;EPSD	TCGA;ICGC;COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P41212	ETV6	P27361	MAPK3	S307	D311N	311	Missense	distal	4	no	9.603	9.576	EPSD	TCGA;ICGC;COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P41212	ETV6	P27361	MAPK3	S307	R309W	309	Missense	proximal	2	no	9.603	9.543	EPSD	TCGA;ICGC;COSMIC;GDSC;CCLE	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P41212	ETV6	P27361	MAPK3	S307	G301W	301	Missense	distal	-6	no	9.603	8.983	EPSD	TCGA;ICGC;COSMIC	9.358	Loss
CMGC_MAPK_ERK1_MAPK3_ST	P41212	ETV6	P27361	MAPK3	S323	E327Q	327	Missense	distal	4	no	16.845	16.754	EPSD	TCGA;ICGC;COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P41212	ETV6	P27361	MAPK3	S439	E444K	444	Missense	distal	5	no	9.952	9.824	EPSD	TCGA;ICGC;COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P41212	ETV6	P27361	MAPK3	S439	R433H	433	Missense	distal	-6	no	9.952	9.948	EPSD	TCGA;ICGC;COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P19419	ELK1	P27361	MAPK3	T133	P134L	134	Missense	proximal	1	no	15.764	6.726	EPSD	TCGA;ICGC	9.358	Loss
CMGC_MAPK_ERK1_MAPK3_ST	P19419	ELK1	P27361	MAPK3	S200	S194L	194	Missense	distal	-6	no	15.230	14.899	EPSD	TCGA;ICGC;COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P19419	ELK1	P27361	MAPK3	S200	S196R	196	Missense	distal	-4	no	15.230	15.153	EPSD	TCGA;ICGC;COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P19419	ELK1	P27361	MAPK3	S200	P201L	201	Missense	proximal	1	no	15.230	6.192	EPSD	TCGA;ICGC;COSMIC	9.358	Loss
CMGC_MAPK_ERK1_MAPK3_ST	P19419	ELK1	P27361	MAPK3	S200	G195R	195	Missense	distal	-5	no	15.230	15.228	EPSD	TCGA;COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P19419	ELK1	P27361	MAPK3	S202	S196R	196	Missense	distal	-6	no	14.103	13.942	EPSD	TCGA;ICGC;COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P19419	ELK1	P27361	MAPK3	S202	P201L	201	Missense	proximal	-1	no	14.103	14.008	EPSD	TCGA;ICGC;COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P19419	ELK1	P27361	MAPK3	S202	G195R	195	Missense	distal	-7	no	14.103	14.148	EPSD	TCGA;COSMIC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P19419	ELK1	P27361	MAPK3	T222	P224S	224	Missense	proximal	2	no	13.614	13.616	EPSD	TCGA;ICGC;COSMIC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P19419	ELK1	P27361	MAPK3	T222	E225K	225	Missense	distal	3	no	13.614	13.603	EPSD	TCGA;ICGC;COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P19419	ELK1	P27361	MAPK3	S304	S308C	308	Missense	distal	4	no	14.893	14.390	EPSD	TCGA;ICGC;COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P19419	ELK1	P27361	MAPK3	S304	A301V	301	Missense	distal	-3	no	14.893	14.912	EPSD	TCGA;ICGC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P19419	ELK1	P27361	MAPK3	S304	G298V	298	Missense	distal	-6	no	14.893	14.626	EPSD	TCGA;ICGC;COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P19419	ELK1	P27361	MAPK3	S304	S303Y	303	Missense	proximal	-1	no	14.893	14.816	EPSD	TCGA;ICGC;COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P19419	ELK1	P27361	MAPK3	S324	S324N	324	Missense	central	0	yes	17.994	0.000	EPSD	TCGA;ICGC;COSMIC	9.358	Loss
CMGC_MAPK_ERK1_MAPK3_ST	P19419	ELK1	P27361	MAPK3	S324	P325L	325	Missense	proximal	1	no	17.994	8.956	EPSD	TCGA;ICGC	9.358	Loss
CMGC_MAPK_ERK1_MAPK3_ST	P19419	ELK1	P27361	MAPK3	S326	S324N	324	Missense	proximal	-2	no	9.502	8.558	EPSD	TCGA;ICGC;COSMIC	9.358	Loss
CMGC_MAPK_ERK1_MAPK3_ST	P19419	ELK1	P27361	MAPK3	S326	P325L	325	Missense	proximal	-1	no	9.502	9.408	EPSD	TCGA;ICGC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P19419	ELK1	P27361	MAPK3	T353	A351V	351	Missense	proximal	-2	no	14.553	15.250	EPSD	TCGA;ICGC;COSMIC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P19419	ELK1	P27361	MAPK3	T368	L372Q	372	Missense	distal	4	no	13.845	13.857	EPSD	TCGA;ICGC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P19419	ELK1	P27361	MAPK3	S383	W379C	379	Missense	distal	-4	no	16.736	16.783	EPSD;PhosphoSitePlus	TCGA	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P19419	ELK1	P27361	MAPK3	S383	F378L	378	Missense	distal	-5	no	16.736	16.811	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P19419	ELK1	P27361	MAPK3	S389	S383T	383	Missense	distal	-6	no	16.106	15.937	PhosphoSitePlus;EPSD	TCGA;COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P19419	ELK1	P27361	MAPK3	S389	A391D	391	Missense	proximal	2	no	16.106	16.133	PhosphoSitePlus;EPSD	TCGA;ICGC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P19419	ELK1	P27361	MAPK3	S422	K427R	427	Missense	distal	5	no	21.537	21.545	EPSD	TCGA;ICGC;COSMIC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P12980	LYL1	P27361	MAPK3	S25	A18E	18	Missense	distal	-7	no	18.155	18.038	EPSD	TCGA;ICGC;COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P12980	LYL1	P27361	MAPK3	S25	C22R	22	Missense	distal	-3	no	18.155	18.295	EPSD	TCGA;ICGC;COSMIC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P12980	LYL1	P27361	MAPK3	S36	E43D	43	Missense	distal	7	no	17.023	17.025	PhosphoSitePlus	TCGA;ICGC;COSMIC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P12980	LYL1	P27361	MAPK3	S52	G59S	59	Missense	distal	7	no	17.100	16.961	EPSD	TCGA;ICGC;COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P08047	SP1	P27361	MAPK3	S42	T49A	49	Missense	distal	7	no	10.411	10.638	EPSD	TCGA;ICGC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P08047	SP1	P27361	MAPK3	S59	L61V	61	Missense	proximal	2	no	16.761	16.759	PhosphoSitePlus;EPSD	TCGA;ICGC;COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P08047	SP1	P27361	MAPK3	S59	S59F	59	Missense	central	0	yes	16.761	0.000	PhosphoSitePlus;EPSD	TCGA;ICGC;COSMIC	9.358	Loss
CMGC_MAPK_ERK1_MAPK3_ST	P08047	SP1	P27361	MAPK3	S73	S69N	69	Missense	distal	-4	no	14.920	14.859	EPSD	TCGA;ICGC;COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P08047	SP1	P27361	MAPK3	S73	C68R	68	Missense	distal	-5	no	14.920	15.037	EPSD	TCGA;ICGC;COSMIC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P08047	SP1	P27361	MAPK3	S73	P74S	74	Missense	proximal	1	no	14.920	5.867	EPSD	TCGA;ICGC;COSMIC	9.358	Loss
CMGC_MAPK_ERK1_MAPK3_ST	P08047	SP1	P27361	MAPK3	S73	S78N	78	Missense	distal	5	no	14.920	14.798	EPSD	TCGA;ICGC;COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P08047	SP1	P27361	MAPK3	T278	V272I	272	Missense	distal	-6	no	14.656	14.587	EPSD	TCGA;ICGC;COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P08047	SP1	P27361	MAPK3	T278	S271N	271	Missense	distal	-7	no	14.656	14.723	EPSD	TCGA;ICGC;COSMIC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P08047	SP1	P27361	MAPK3	T453	S446C	446	Missense	distal	-7	no	14.945	15.214	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P08047	SP1	P27361	MAPK3	S588	D590E	590	Missense	proximal	2	no	15.263	15.265	EPSD	TCGA;ICGC;COSMIC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P08047	SP1	P27361	MAPK3	S588	S588N	588	Missense	central	0	yes	15.263	0.000	EPSD	TCGA;ICGC;COSMIC	9.358	Loss
CMGC_MAPK_ERK1_MAPK3_ST	P08047	SP1	P27361	MAPK3	S661	R666H	666	Missense	distal	5	no	10.288	10.324	EPSD	TCGA;ICGC;COSMIC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P08047	SP1	P27361	MAPK3	T739	I744F	744	Missense	distal	5	no	15.700	15.668	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P08047	SP1	P27361	MAPK3	T739	A742T	742	Missense	distal	3	no	15.700	15.730	EPSD;PhosphoSitePlus	TCGA;ICGC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P08047	SP1	P27361	MAPK3	T739	G736S	736	Missense	distal	-3	no	15.700	15.732	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P55211	CASP9	P27361	MAPK3	S87	D83Y	83	Missense	distal	-4	no	12.012	11.944	EPSD	TCGA;ICGC;COSMIC;CCLE	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P55211	CASP9	P27361	MAPK3	S87	G81D	81	Missense	distal	-6	no	12.012	12.014	EPSD	TCGA;ICGC;COSMIC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P55211	CASP9	P27361	MAPK3	T107	E114D	114	Missense	distal	7	no	14.149	14.151	EPSD	TCGA;ICGC;COSMIC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P55211	CASP9	P27361	MAPK3	T107	P101A	101	Missense	distal	-6	no	14.149	13.917	EPSD	TCGA;ICGC;COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P55211	CASP9	P27361	MAPK3	T107	P113S	113	Missense	distal	6	no	14.149	14.278	EPSD	TCGA;ICGC;COSMIC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P55211	CASP9	P27361	MAPK3	S302	S307F	307	Missense	distal	5	no	16.569	16.144	EPSD	TCGA;ICGC;COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P55211	CASP9	P27361	MAPK3	S307	S307F	307	Missense	central	0	yes	16.881	0.000	EPSD	TCGA;ICGC;COSMIC	9.358	Loss
CMGC_MAPK_ERK1_MAPK3_ST	O43561	LAT	P27361	MAPK3	S84	P82S	82	Missense	proximal	-2	no	17.347	16.271	EPSD	TCGA;COSMIC;CCLE	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	O43561	LAT	P27361	MAPK3	S240	A238S	238	Missense	proximal	-2	no	9.498	10.773	EPSD	TCGA	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	O43561	LAT	P27361	MAPK3	S240	P236T	236	Missense	distal	-4	no	9.498	9.467	EPSD	TCGA;COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	O43561	LAT	P27361	MAPK3	S241	A238S	238	Missense	distal	-3	no	10.504	10.596	EPSD	TCGA	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	O43561	LAT	P27361	MAPK3	S241	P236T	236	Missense	distal	-5	no	10.504	10.494	EPSD	TCGA;COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q15788	NCOA1	P27361	MAPK3	S16	S22L	22	Missense	distal	6	no	12.112	11.756	EPSD	TCGA;ICGC;COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q15788	NCOA1	P27361	MAPK3	S22	S22L	22	Missense	central	0	yes	17.253	0.000	EPSD	TCGA;ICGC;COSMIC	9.358	Loss
CMGC_MAPK_ERK1_MAPK3_ST	Q15788	NCOA1	P27361	MAPK3	S97	D91N	91	Missense	distal	-6	no	9.649	9.588	EPSD	TCGA;ICGC;COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q15788	NCOA1	P27361	MAPK3	S325	R320H	320	Missense	distal	-5	no	18.757	18.766	EPSD	TCGA;ICGC;COSMIC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q15788	NCOA1	P27361	MAPK3	S325	R329K	329	Missense	distal	4	no	18.757	18.765	EPSD	TCGA;ICGC;COSMIC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q15788	NCOA1	P27361	MAPK3	S325	G321S	321	Missense	distal	-4	no	18.757	18.795	EPSD	TCGA;ICGC;COSMIC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q15788	NCOA1	P27361	MAPK3	S325	A323V	323	Missense	proximal	-2	no	18.757	19.454	EPSD	TCGA;ICGC;COSMIC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q15788	NCOA1	P27361	MAPK3	S325	G321D	321	Missense	distal	-4	no	18.757	18.760	EPSD	TCGA;ICGC;COSMIC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q15788	NCOA1	P27361	MAPK3	S325	R329G	329	Missense	distal	4	no	18.757	18.743	EPSD	TCGA;ICGC;COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q15788	NCOA1	P27361	MAPK3	S372	H368Y	368	Missense	distal	-4	no	16.818	16.778	EPSD	TCGA;ICGC;COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q15788	NCOA1	P27361	MAPK3	S372	S372C	372	Missense	central	0	yes	16.818	0.000	EPSD	TCGA;ICGC;COSMIC	9.358	Loss
CMGC_MAPK_ERK1_MAPK3_ST	Q15788	NCOA1	P27361	MAPK3	S372	G370R	370	Missense	proximal	-2	no	16.818	17.535	EPSD	TCGA;ICGC;COSMIC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q15788	NCOA1	P27361	MAPK3	S372	D376E	376	Missense	distal	4	no	16.818	16.838	EPSD	TCGA;ICGC;COSMIC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q15788	NCOA1	P27361	MAPK3	S395	P388L	388	Missense	distal	-7	no	14.953	15.060	EPSD	TCGA;ICGC;COSMIC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q15788	NCOA1	P27361	MAPK3	S517	V519I	519	Missense	proximal	2	no	16.656	16.646	EPSD	TCGA;ICGC;COSMIC;GDSC;CCLE	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q15788	NCOA1	P27361	MAPK3	S517	S513L	513	Missense	distal	-4	no	16.656	16.516	EPSD	TCGA;ICGC;COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q15788	NCOA1	P27361	MAPK3	S517	P518S	518	Missense	proximal	1	no	16.656	7.602	EPSD	TCGA;ICGC;COSMIC	9.358	Loss
CMGC_MAPK_ERK1_MAPK3_ST	Q15788	NCOA1	P27361	MAPK3	S517	S516R	516	Missense	proximal	-1	no	16.656	16.614	EPSD	TCGA;ICGC;COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q15788	NCOA1	P27361	MAPK3	S517	S513A	513	Missense	distal	-4	no	16.656	16.524	EPSD	TCGA;ICGC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q15788	NCOA1	P27361	MAPK3	T539	S540Y	540	Missense	proximal	1	no	7.410	9.415	EPSD	TCGA;ICGC	9.358	Gain
CMGC_MAPK_ERK1_MAPK3_ST	Q15788	NCOA1	P27361	MAPK3	S558	S551F	551	Missense	distal	-7	no	14.632	14.851	EPSD	TCGA;ICGC;COSMIC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q15788	NCOA1	P27361	MAPK3	S569	R572T	572	Missense	distal	3	no	15.846	15.854	EPSD	TCGA;ICGC;COSMIC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q15788	NCOA1	P27361	MAPK3	S569	S566A	566	Missense	distal	-3	no	15.846	15.754	EPSD	TCGA;ICGC;COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q15788	NCOA1	P27361	MAPK3	S603	N600K	600	Missense	distal	-3	no	9.461	9.455	EPSD	TCGA;ICGC;COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q15788	NCOA1	P27361	MAPK3	S620	R618I	618	Missense	proximal	-2	no	9.542	9.104	EPSD	TCGA;ICGC;COSMIC	9.358	Loss
CMGC_MAPK_ERK1_MAPK3_ST	Q15788	NCOA1	P27361	MAPK3	S679	S672L	672	Missense	distal	-7	no	10.883	11.028	EPSD	TCGA;ICGC;COSMIC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q15788	NCOA1	P27361	MAPK3	S679	S675Y	675	Missense	distal	-4	no	10.883	10.780	EPSD	TCGA;ICGC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q15788	NCOA1	P27361	MAPK3	S679	R686W	686	Missense	distal	7	no	10.883	11.460	EPSD	TCGA;ICGC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q15788	NCOA1	P27361	MAPK3	S698	S698R	698	Missense	central	0	yes	15.369	0.000	EPSD	TCGA;ICGC;COSMIC	9.358	Loss
CMGC_MAPK_ERK1_MAPK3_ST	Q15788	NCOA1	P27361	MAPK3	T763	L766M	766	Missense	distal	3	no	14.531	14.501	EPSD	TCGA;ICGC;COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q15788	NCOA1	P27361	MAPK3	T763	L768V	768	Missense	distal	5	no	14.531	14.535	EPSD	TCGA;ICGC;COSMIC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q15788	NCOA1	P27361	MAPK3	T763	K758N	758	Missense	distal	-5	no	14.531	14.537	EPSD	TCGA;ICGC;COSMIC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q15788	NCOA1	P27361	MAPK3	T763	L760V	760	Missense	distal	-3	no	14.531	14.534	EPSD	TCGA;ICGC;COSMIC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q15788	NCOA1	P27361	MAPK3	T789	P794H	794	Missense	distal	5	no	14.106	14.041	EPSD	TCGA;ICGC;COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q15788	NCOA1	P27361	MAPK3	T789	T792I	792	Missense	distal	3	no	14.106	14.068	EPSD	TCGA;ICGC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q15788	NCOA1	P27361	MAPK3	T979	I983M	983	Missense	distal	4	no	15.913	15.875	EPSD	TCGA;ICGC;COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q15788	NCOA1	P27361	MAPK3	T979	P975T	975	Missense	distal	-4	no	15.913	15.882	EPSD	TCGA;ICGC;COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q15788	NCOA1	P27361	MAPK3	S997	S999F	999	Missense	proximal	2	no	16.555	16.505	EPSD	TCGA;ICGC;COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q15788	NCOA1	P27361	MAPK3	S999	S999F	999	Missense	central	0	yes	15.214	0.000	EPSD	TCGA;ICGC;COSMIC	9.358	Loss
CMGC_MAPK_ERK1_MAPK3_ST	Q15788	NCOA1	P27361	MAPK3	S1006	S999F	999	Missense	distal	-7	no	15.764	15.984	EPSD	TCGA;ICGC;COSMIC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q15788	NCOA1	P27361	MAPK3	T1026	P1022A	1022	Missense	distal	-4	no	13.828	13.724	EPSD	TCGA;ICGC;COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q15788	NCOA1	P27361	MAPK3	T1026	S1033L	1033	Missense	distal	7	no	13.828	14.098	EPSD	TCGA;ICGC;COSMIC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q15788	NCOA1	P27361	MAPK3	T1026	A1031D	1031	Missense	distal	5	no	13.828	14.041	EPSD	TCGA;ICGC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q15788	NCOA1	P27361	MAPK3	S1033	M1036I	1036	Missense	distal	3	no	14.922	14.932	EPSD	TCGA;ICGC;COSMIC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q15788	NCOA1	P27361	MAPK3	S1033	P1034S	1034	Missense	proximal	1	no	14.922	5.868	EPSD	TCGA;ICGC;COSMIC	9.358	Loss
CMGC_MAPK_ERK1_MAPK3_ST	Q15788	NCOA1	P27361	MAPK3	S1033	S1033L	1033	Missense	central	0	yes	14.922	0.000	EPSD	TCGA;ICGC;COSMIC	9.358	Loss
CMGC_MAPK_ERK1_MAPK3_ST	Q15788	NCOA1	P27361	MAPK3	S1033	A1031D	1031	Missense	proximal	-2	no	14.922	15.666	EPSD	TCGA;ICGC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q15788	NCOA1	P27361	MAPK3	S1033	G1037D	1037	Missense	distal	4	no	14.922	14.963	EPSD	TCGA;ICGC;COSMIC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q15788	NCOA1	P27361	MAPK3	S1250	A1243P	1243	Missense	distal	-7	no	15.421	15.309	EPSD	TCGA;ICGC;COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q15788	NCOA1	P27361	MAPK3	S1250	P1251T	1251	Missense	proximal	1	no	15.421	6.544	EPSD	TCGA;ICGC;COSMIC	9.358	Loss
CMGC_MAPK_ERK1_MAPK3_ST	Q15788	NCOA1	P27361	MAPK3	T1271	S1275F	1275	Missense	distal	4	no	16.115	15.701	EPSD	TCGA;GDSC;CCLE	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q15788	NCOA1	P27361	MAPK3	T1271	Q1270K	1270	Missense	proximal	-1	no	16.115	16.141	EPSD	TCGA	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q15788	NCOA1	P27361	MAPK3	T1271	Q1270E	1270	Missense	proximal	-1	no	16.115	16.171	EPSD	TCGA;ICGC;COSMIC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q15788	NCOA1	P27361	MAPK3	T1271	S1266Y	1266	Missense	distal	-5	no	16.115	16.051	EPSD	TCGA;ICGC;COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q15788	NCOA1	P27361	MAPK3	S1279	S1275F	1275	Missense	distal	-4	no	15.028	14.839	EPSD	TCGA;GDSC;CCLE	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q15788	NCOA1	P27361	MAPK3	S1279	W1285L	1285	Missense	distal	6	no	15.028	15.736	EPSD	TCGA;ICGC;COSMIC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q15788	NCOA1	P27361	MAPK3	T1426	Q1430H	1430	Missense	distal	4	no	20.148	20.198	EPSD	TCGA	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q96RK0	CIC	P27361	MAPK3	S105	E104K	104	Missense	proximal	-1	no	18.171	18.141	EPSD	TCGA;COSMIC;GDSC;CCLE	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q96RK0	CIC	P27361	MAPK3	S191	N193Y	193	Missense	proximal	2	no	15.426	15.421	EPSD	TCGA;COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q96RK0	CIC	P27361	MAPK3	S191	E186Q	186	Missense	distal	-5	no	15.426	15.407	EPSD	TCGA;COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q96RK0	CIC	P27361	MAPK3	S191	G189E	189	Missense	proximal	-2	no	15.426	15.896	EPSD	TCGA;COSMIC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q96RK0	CIC	P27361	MAPK3	S349	S349L	349	Missense	central	0	yes	9.953	0.000	EPSD	TCGA	9.358	Loss
CMGC_MAPK_ERK1_MAPK3_ST	Q96RK0	CIC	P27361	MAPK3	S496	R492W	492	Missense	distal	-4	no	17.896	17.689	EPSD	TCGA;ICGC;COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q96RK0	CIC	P27361	MAPK3	S496	F495L	495	Missense	proximal	-1	no	17.896	18.012	EPSD	TCGA;ICGC;COSMIC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q96RK0	CIC	P27361	MAPK3	S496	S502F	502	Missense	distal	6	no	17.896	17.182	EPSD	TCGA;ICGC;COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q96RK0	CIC	P27361	MAPK3	S496	S501F	501	Missense	distal	5	no	17.896	17.472	EPSD	TCGA;ICGC;COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q96RK0	CIC	P27361	MAPK3	S496	R492Q	492	Missense	distal	-4	no	17.896	17.906	EPSD	TCGA;ICGC;COSMIC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q96RK0	CIC	P27361	MAPK3	S502	F495L	495	Missense	distal	-7	no	10.102	10.028	EPSD	TCGA;ICGC;COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q96RK0	CIC	P27361	MAPK3	S502	S502F	502	Missense	central	0	yes	10.102	0.000	EPSD	TCGA;ICGC;COSMIC	9.358	Loss
CMGC_MAPK_ERK1_MAPK3_ST	Q96RK0	CIC	P27361	MAPK3	S502	S501F	501	Missense	proximal	-1	no	10.102	9.898	EPSD	TCGA;ICGC;COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q96RK0	CIC	P27361	MAPK3	S538	S543L	543	Missense	distal	5	no	15.087	14.816	EPSD	TCGA;ICGC;COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q96RK0	CIC	P27361	MAPK3	T583	A582P	582	Missense	proximal	-1	no	16.618	16.757	EPSD	TCGA;ICGC;COSMIC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q96RK0	CIC	P27361	MAPK3	T583	R589Q	589	Missense	distal	6	no	16.618	16.549	EPSD	TCGA;ICGC;COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q96RK0	CIC	P27361	MAPK3	T583	G580A	580	Missense	distal	-3	no	16.618	16.559	EPSD	TCGA;ICGC;COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q96RK0	CIC	P27361	MAPK3	T583	F590L	590	Missense	distal	7	no	16.618	16.397	EPSD	TCGA;ICGC;COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q96RK0	CIC	P27361	MAPK3	T583	R589W	589	Missense	distal	6	no	16.618	15.795	EPSD	TCGA;ICGC;COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q96RK0	CIC	P27361	MAPK3	T583	P576S	576	Missense	distal	-7	no	16.618	16.580	EPSD	TCGA;ICGC;COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q96RK0	CIC	P27361	MAPK3	S700	E698K	698	Missense	proximal	-2	no	15.564	14.870	EPSD	TCGA;ICGC;COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q96RK0	CIC	P27361	MAPK3	S739	H743L	743	Missense	distal	4	no	15.295	15.232	EPSD	TCGA;ICGC;COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q96RK0	CIC	P27361	MAPK3	S739	P742L	742	Missense	distal	3	no	15.295	15.258	EPSD	TCGA;ICGC;COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q96RK0	CIC	P27361	MAPK3	S739	A737T	737	Missense	proximal	-2	no	15.295	16.660	EPSD	TCGA;ICGC;COSMIC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q96RK0	CIC	P27361	MAPK3	S739	A746V	746	Missense	distal	7	no	15.295	15.267	EPSD	TCGA;ICGC;COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q96RK0	CIC	P27361	MAPK3	S904	P909Q	909	Missense	distal	5	no	16.255	16.153	EPSD	TCGA;ICGC;COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q96RK0	CIC	P27361	MAPK3	S904	A900P	900	Missense	distal	-4	no	16.255	16.360	EPSD	TCGA;ICGC;COSMIC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q96RK0	CIC	P27361	MAPK3	S904	P910L	910	Missense	distal	6	no	16.255	16.029	EPSD	TCGA;ICGC;COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q96RK0	CIC	P27361	MAPK3	S904	P905L	905	Missense	proximal	1	no	16.255	7.217	EPSD	TCGA;ICGC;COSMIC	9.358	Loss
CMGC_MAPK_ERK1_MAPK3_ST	Q96RK0	CIC	P27361	MAPK3	S946	S950L	950	Missense	distal	4	no	16.358	16.154	EPSD	TCGA;ICGC;COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q96RK0	CIC	P27361	MAPK3	S946	P947S	947	Missense	proximal	1	no	16.358	7.304	EPSD	TCGA;ICGC;COSMIC	9.358	Loss
CMGC_MAPK_ERK1_MAPK3_ST	Q96RK0	CIC	P27361	MAPK3	S982	V978M	978	Missense	distal	-4	no	19.417	19.389	EPSD	TCGA;ICGC;COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q96RK0	CIC	P27361	MAPK3	S1173	P1177L	1177	Missense	distal	4	no	16.957	16.803	EPSD	TCGA;ICGC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q96RK0	CIC	P27361	MAPK3	S1173	R1171Q	1171	Missense	proximal	-2	no	16.957	16.594	EPSD	TCGA;COSMIC;GDSC;CCLE	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q96RK0	CIC	P27361	MAPK3	T1228	E1224Q	1224	Missense	distal	-4	no	15.870	15.828	EPSD	TCGA;ICGC;COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q96RK0	CIC	P27361	MAPK3	T1240	E1237K	1237	Missense	distal	-3	no	16.065	16.034	EPSD	TCGA;COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q96RK0	CIC	P27361	MAPK3	T1240	A1243T	1243	Missense	distal	3	no	16.065	16.095	EPSD	TCGA	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q96RK0	CIC	P27361	MAPK3	S1246	A1243T	1243	Missense	distal	-3	no	18.368	18.430	EPSD	TCGA	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q96RK0	CIC	P27361	MAPK3	T1291	S1294R	1294	Missense	distal	3	no	16.488	16.466	EPSD	TCGA;COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q96RK0	CIC	P27361	MAPK3	S1294	S1294R	1294	Missense	central	0	yes	19.937	0.000	EPSD	TCGA;COSMIC	9.358	Loss
CMGC_MAPK_ERK1_MAPK3_ST	Q96RK0	CIC	P27361	MAPK3	T1318	R1321H	1321	Missense	distal	3	no	14.369	14.377	EPSD	TCGA;COSMIC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q96RK0	CIC	P27361	MAPK3	T1318	D1317E	1317	Missense	proximal	-1	no	14.369	14.391	EPSD	TCGA;ICGC;COSMIC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q96RK0	CIC	P27361	MAPK3	T1318	K1322Q	1322	Missense	distal	4	no	14.369	14.316	EPSD	TCGA;ICGC;COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q96RK0	CIC	P27361	MAPK3	S1373	S1378F	1378	Missense	distal	5	no	15.892	15.467	EPSD	TCGA;COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q96RK0	CIC	P27361	MAPK3	S1373	P1374L	1374	Missense	proximal	1	no	15.892	6.854	EPSD	TCGA;COSMIC	9.358	Loss
CMGC_MAPK_ERK1_MAPK3_ST	Q96RK0	CIC	P27361	MAPK3	S1382	S1378F	1378	Missense	distal	-4	no	14.315	14.126	EPSD	TCGA;COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q96RK0	CIC	P27361	MAPK3	S1382	R1384W	1384	Missense	proximal	2	no	14.315	14.255	EPSD	TCGA;ICGC;COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q96RK0	CIC	P27361	MAPK3	S1409	R1412L	1412	Missense	distal	3	no	18.257	18.247	PhosphoSitePlus;EPSD	TCGA;COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q96RK0	CIC	P27361	MAPK3	S1409	S1409L	1409	Missense	central	0	yes	18.257	0.000	PhosphoSitePlus;EPSD	TCGA;ICGC;COSMIC	9.358	Loss
CMGC_MAPK_ERK1_MAPK3_ST	Q96RK0	CIC	P27361	MAPK3	S1409	A1403T	1403	Missense	distal	-6	no	18.257	18.405	PhosphoSitePlus;EPSD	TCGA;COSMIC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q96RK0	CIC	P27361	MAPK3	T1426	S1429I	1429	Missense	distal	3	no	14.172	14.120	EPSD	TCGA;ICGC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P61586	RHOA	P27361	MAPK3	S73	D76Y	76	Missense	distal	3	no	11.807	11.787	EPSD	TCGA;ICGC;COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P61586	RHOA	P27361	MAPK3	S73	L69P	69	Missense	distal	-4	no	11.807	11.920	EPSD	TCGA;ICGC;COSMIC;GDSC;CCLE	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P61586	RHOA	P27361	MAPK3	S73	R68C	68	Missense	distal	-5	no	11.807	11.691	EPSD	TCGA;ICGC;COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P61586	RHOA	P27361	MAPK3	S73	R70S	70	Missense	distal	-3	no	11.807	11.845	EPSD	TCGA;ICGC;COSMIC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P61586	RHOA	P27361	MAPK3	S73	Y66N	66	Missense	distal	-7	no	11.807	11.756	EPSD	TCGA;ICGC;COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P61586	RHOA	P27361	MAPK3	S73	S73F	73	Missense	central	0	yes	11.807	0.000	EPSD	TCGA;ICGC;COSMIC;CCLE	9.358	Loss
CMGC_MAPK_ERK1_MAPK3_ST	P61586	RHOA	P27361	MAPK3	S73	S73P	73	Missense	central	0	yes	11.807	0.000	EPSD	TCGA;ICGC;COSMIC	9.358	Loss
CMGC_MAPK_ERK1_MAPK3_ST	P61586	RHOA	P27361	MAPK3	S73	P75S	75	Missense	proximal	2	no	11.807	11.809	EPSD	TCGA;ICGC;COSMIC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P61586	RHOA	P27361	MAPK3	S73	L69M	69	Missense	distal	-4	no	11.807	11.767	EPSD	TCGA;ICGC;COSMIC;CCLE	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P61586	RHOA	P27361	MAPK3	S88	E93K	93	Missense	distal	5	no	17.374	17.246	PhosphoSitePlus;EPSD	TCGA;ICGC;COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P61586	RHOA	P27361	MAPK3	T100	F106L	106	Missense	distal	6	no	13.651	14.008	EPSD;PhosphoSitePlus	TCGA;COSMIC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P61586	RHOA	P27361	MAPK3	T100	F106V	106	Missense	distal	6	no	13.651	13.926	EPSD;PhosphoSitePlus	TCGA;COSMIC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P61586	RHOA	P27361	MAPK3	T100	P96S	96	Missense	distal	-4	no	13.651	13.678	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P61586	RHOA	P27361	MAPK3	T100	E93K	93	Missense	distal	-7	no	13.651	13.702	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q92793	CREBBP	P27361	MAPK3	S23	D29Y	29	Missense	distal	6	no	10.043	9.837	EPSD	TCGA;ICGC;COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q92793	CREBBP	P27361	MAPK3	S93	G98C	98	Missense	distal	5	no	16.984	16.525	PhosphoSitePlus	TCGA;ICGC;COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q92793	CREBBP	P27361	MAPK3	S121	G119V	119	Missense	proximal	-2	no	14.842	15.305	EPSD	TCGA;ICGC;COSMIC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q92793	CREBBP	P27361	MAPK3	S745	M739I	739	Missense	distal	-6	no	14.467	14.491	EPSD	TCGA	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q92793	CREBBP	P27361	MAPK3	S745	P746S	746	Missense	proximal	1	no	14.467	5.414	EPSD	TCGA;COSMIC	9.358	Loss
CMGC_MAPK_ERK1_MAPK3_ST	Q92793	CREBBP	P27361	MAPK3	S745	V751I	751	Missense	distal	6	no	14.467	14.336	EPSD	TCGA;COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q92793	CREBBP	P27361	MAPK3	S745	R742C	742	Missense	distal	-3	no	14.467	14.327	EPSD	TCGA;COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q92793	CREBBP	P27361	MAPK3	S1019	E1012K	1012	Missense	distal	-7	no	9.471	9.522	EPSD	TCGA;COSMIC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q92793	CREBBP	P27361	MAPK3	S1019	E1024D	1024	Missense	distal	5	no	9.471	9.453	EPSD	TCGA	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q92793	CREBBP	P27361	MAPK3	S1019	E1023K	1023	Missense	distal	4	no	9.471	9.432	EPSD	TCGA;COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q92793	CREBBP	P27361	MAPK3	S1019	S1013P	1013	Missense	distal	-6	no	9.471	9.386	EPSD	TCGA;COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q92793	CREBBP	P27361	MAPK3	S1386	F1389S	1389	Missense	distal	3	no	9.555	9.620	EPSD	TCGA;COSMIC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q92793	CREBBP	P27361	MAPK3	S1386	M1385I	1385	Missense	proximal	-1	no	9.555	9.579	EPSD	TCGA;COSMIC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q92793	CREBBP	P27361	MAPK3	S1386	R1392Q	1392	Missense	distal	6	no	9.555	9.486	EPSD	TCGA;COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q92793	CREBBP	P27361	MAPK3	S1578	Q1579H	1579	Missense	proximal	1	no	9.970	10.158	EPSD	TCGA	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q92793	CREBBP	P27361	MAPK3	S1578	T1575N	1575	Missense	distal	-3	no	9.970	9.956	EPSD	TCGA	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q92793	CREBBP	P27361	MAPK3	S1763	G1757C	1757	Missense	distal	-6	no	17.993	17.496	EPSD	TCGA;COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q92793	CREBBP	P27361	MAPK3	S1763	R1768C	1768	Missense	distal	5	no	17.993	17.614	EPSD	TCGA;COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q92793	CREBBP	P27361	MAPK3	S1763	S1767L	1767	Missense	distal	4	no	17.993	17.790	EPSD	TCGA;COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q92793	CREBBP	P27361	MAPK3	S1763	E1766K	1766	Missense	distal	3	no	17.993	17.982	EPSD	TCGA;COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q92793	CREBBP	P27361	MAPK3	S1884	S1881N	1881	Missense	distal	-3	no	17.209	17.165	EPSD	TCGA	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q92793	CREBBP	P27361	MAPK3	T1894	P1900A	1900	Missense	distal	6	no	9.983	9.587	EPSD	TCGA;COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q92793	CREBBP	P27361	MAPK3	T1899	P1900A	1900	Missense	proximal	1	no	18.704	9.464	EPSD	TCGA;COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q92793	CREBBP	P27361	MAPK3	T1899	P1903L	1903	Missense	distal	4	no	18.704	18.549	EPSD	TCGA	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q92793	CREBBP	P27361	MAPK3	T1990	Q1994H	1994	Missense	distal	4	no	12.179	12.229	EPSD	TCGA;COSMIC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q92793	CREBBP	P27361	MAPK3	T1990	R1985C	1985	Missense	distal	-5	no	12.179	12.062	EPSD	TCGA;COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q92793	CREBBP	P27361	MAPK3	T1990	A1996T	1996	Missense	distal	6	no	12.179	12.549	EPSD	TCGA;COSMIC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q92793	CREBBP	P27361	MAPK3	S1993	Q1994H	1994	Missense	proximal	1	no	9.797	9.985	EPSD	TCGA;COSMIC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q92793	CREBBP	P27361	MAPK3	S1993	A1996T	1996	Missense	distal	3	no	9.797	9.827	EPSD	TCGA;COSMIC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q92793	CREBBP	P27361	MAPK3	S2063	A2066T	2066	Missense	distal	3	no	15.063	15.093	EPSD	TCGA;COSMIC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q92793	CREBBP	P27361	MAPK3	S2076	S2079F	2079	Missense	distal	3	no	16.918	16.853	EPSD	TCGA;COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q92793	CREBBP	P27361	MAPK3	S2076	R2072W	2072	Missense	distal	-4	no	16.918	16.710	EPSD	TCGA;COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q92793	CREBBP	P27361	MAPK3	S2076	P2077S	2077	Missense	proximal	1	no	16.918	7.864	EPSD	TCGA	9.358	Loss
CMGC_MAPK_ERK1_MAPK3_ST	Q92793	CREBBP	P27361	MAPK3	S2076	R2072Q	2072	Missense	distal	-4	no	16.918	16.928	EPSD	TCGA;COSMIC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q92793	CREBBP	P27361	MAPK3	S2078	S2079F	2079	Missense	proximal	1	no	9.749	12.589	EPSD	TCGA;COSMIC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q92793	CREBBP	P27361	MAPK3	S2078	R2072W	2072	Missense	distal	-6	no	9.749	9.227	EPSD	TCGA;COSMIC	9.358	Loss
CMGC_MAPK_ERK1_MAPK3_ST	Q92793	CREBBP	P27361	MAPK3	S2078	P2077S	2077	Missense	proximal	-1	no	9.749	9.743	EPSD	TCGA	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q92793	CREBBP	P27361	MAPK3	S2078	R2072Q	2072	Missense	distal	-6	no	9.749	9.759	EPSD	TCGA;COSMIC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q92793	CREBBP	P27361	MAPK3	S2079	S2079F	2079	Missense	central	0	yes	17.643	0.000	EPSD	TCGA;COSMIC	9.358	Loss
CMGC_MAPK_ERK1_MAPK3_ST	Q92793	CREBBP	P27361	MAPK3	S2079	R2072W	2072	Missense	distal	-7	no	17.643	17.888	EPSD	TCGA;COSMIC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q92793	CREBBP	P27361	MAPK3	S2079	P2077S	2077	Missense	proximal	-2	no	17.643	16.567	EPSD	TCGA	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q92793	CREBBP	P27361	MAPK3	S2079	R2072Q	2072	Missense	distal	-7	no	17.643	17.642	EPSD	TCGA;COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q92793	CREBBP	P27361	MAPK3	S2307	M2301I	2301	Missense	distal	-6	no	15.501	15.525	EPSD	TCGA;COSMIC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q92793	CREBBP	P27361	MAPK3	S2315	S2315C	2315	Missense	central	0	yes	16.838	0.000	EPSD	TCGA;COSMIC	9.358	Loss
CMGC_MAPK_ERK1_MAPK3_ST	Q92793	CREBBP	P27361	MAPK3	S2315	Q2317K	2317	Missense	proximal	2	no	16.838	16.843	EPSD	TCGA;COSMIC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q92793	CREBBP	P27361	MAPK3	S2328	S2328L	2328	Missense	central	0	yes	9.512	0.000	EPSD	TCGA;COSMIC;CCLE	9.358	Loss
CMGC_MAPK_ERK1_MAPK3_ST	Q92793	CREBBP	P27361	MAPK3	S2328	P2331S	2331	Missense	distal	3	no	9.512	9.508	EPSD	TCGA;COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q92793	CREBBP	P27361	MAPK3	S2345	S2340N	2340	Missense	distal	-5	no	15.983	15.943	EPSD	TCGA	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q92793	CREBBP	P27361	MAPK3	S2345	R2344Q	2344	Missense	proximal	-1	no	15.983	15.944	EPSD	TCGA;COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q92793	CREBBP	P27361	MAPK3	S2345	R2344W	2344	Missense	proximal	-1	no	15.983	15.745	EPSD	TCGA;COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q92793	CREBBP	P27361	MAPK3	S2345	A2347V	2347	Missense	proximal	2	no	15.983	15.996	EPSD	TCGA;COSMIC;GDSC;CCLE	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q92793	CREBBP	P27361	MAPK3	S2345	S2338F	2338	Missense	distal	-7	no	15.983	16.202	EPSD	TCGA	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q92793	CREBBP	P27361	MAPK3	S2345	S2351F	2351	Missense	distal	6	no	15.983	15.270	EPSD	TCGA;COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q92793	CREBBP	P27361	MAPK3	S2351	R2344Q	2344	Missense	distal	-7	no	15.918	15.917	EPSD	TCGA;COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q92793	CREBBP	P27361	MAPK3	S2351	R2353L	2353	Missense	proximal	2	no	15.918	15.908	EPSD	TCGA;COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q92793	CREBBP	P27361	MAPK3	S2351	S2356F	2356	Missense	distal	5	no	15.918	15.494	EPSD	TCGA;COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q92793	CREBBP	P27361	MAPK3	S2351	R2344W	2344	Missense	distal	-7	no	15.918	16.164	EPSD	TCGA;COSMIC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q92793	CREBBP	P27361	MAPK3	S2351	A2347V	2347	Missense	distal	-4	no	15.918	15.898	EPSD	TCGA;COSMIC;GDSC;CCLE	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q92793	CREBBP	P27361	MAPK3	S2351	S2351F	2351	Missense	central	0	yes	15.918	0.000	EPSD	TCGA;COSMIC	9.358	Loss
CMGC_MAPK_ERK1_MAPK3_ST	Q92793	CREBBP	P27361	MAPK3	S2356	R2353L	2353	Missense	distal	-3	no	9.396	9.359	EPSD	TCGA;COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q92793	CREBBP	P27361	MAPK3	S2356	S2356F	2356	Missense	central	0	yes	9.396	0.000	EPSD	TCGA;COSMIC	9.358	Loss
CMGC_MAPK_ERK1_MAPK3_ST	Q92793	CREBBP	P27361	MAPK3	S2356	S2351F	2351	Missense	distal	-5	no	9.396	9.262	EPSD	TCGA;COSMIC	9.358	Loss
CMGC_MAPK_ERK1_MAPK3_ST	Q92793	CREBBP	P27361	MAPK3	S2361	S2356F	2356	Missense	distal	-5	no	10.060	9.926	EPSD	TCGA;COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q92793	CREBBP	P27361	MAPK3	S2362	S2356F	2356	Missense	distal	-6	no	16.541	16.074	EPSD	TCGA;COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q92793	CREBBP	P27361	MAPK3	S2364	P2371L	2371	Missense	distal	7	no	17.386	17.579	EPSD	TCGA;COSMIC;GDSC;CCLE	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q92793	CREBBP	P27361	MAPK3	S2372	S2372L	2372	Missense	central	0	yes	16.983	0.000	EPSD	TCGA;COSMIC	9.358	Loss
CMGC_MAPK_ERK1_MAPK3_ST	Q92793	CREBBP	P27361	MAPK3	S2372	P2371L	2371	Missense	proximal	-1	no	16.983	16.889	EPSD	TCGA;COSMIC;GDSC;CCLE	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q92793	CREBBP	P27361	MAPK3	S2377	G2381V	2381	Missense	distal	4	no	16.925	16.863	EPSD	TCGA;COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q92793	CREBBP	P27361	MAPK3	S2377	G2381C	2381	Missense	distal	4	no	16.925	16.582	EPSD	TCGA;COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q92793	CREBBP	P27361	MAPK3	S2377	S2372L	2372	Missense	distal	-5	no	16.925	16.866	EPSD	TCGA;COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q92793	CREBBP	P27361	MAPK3	S2377	H2384Q	2384	Missense	distal	7	no	16.925	16.987	EPSD	TCGA;COSMIC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q92793	CREBBP	P27361	MAPK3	S2377	S2382F	2382	Missense	distal	5	no	16.925	16.501	EPSD	TCGA;COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q92793	CREBBP	P27361	MAPK3	S2377	P2371L	2371	Missense	distal	-6	no	16.925	16.678	EPSD	TCGA;COSMIC;GDSC;CCLE	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q92793	CREBBP	P27361	MAPK3	S2382	G2381V	2381	Missense	proximal	-1	no	16.838	16.820	EPSD	TCGA;COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q92793	CREBBP	P27361	MAPK3	S2382	G2381C	2381	Missense	proximal	-1	no	16.838	16.677	EPSD	TCGA;COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q92793	CREBBP	P27361	MAPK3	S2382	H2384Q	2384	Missense	proximal	2	no	16.838	16.832	EPSD	TCGA;COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q92793	CREBBP	P27361	MAPK3	S2382	P2385L	2385	Missense	distal	3	no	16.838	16.802	EPSD	TCGA;COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q92793	CREBBP	P27361	MAPK3	S2382	S2382F	2382	Missense	central	0	yes	16.838	0.000	EPSD	TCGA;COSMIC	9.358	Loss
CMGC_MAPK_ERK1_MAPK3_ST	Q92793	CREBBP	P27361	MAPK3	S2422	D2429N	2429	Missense	distal	7	no	9.858	9.917	EPSD	TCGA;COSMIC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q92793	CREBBP	P27361	MAPK3	S2425	D2429N	2429	Missense	distal	4	no	10.188	10.161	EPSD	TCGA;COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q01196	RUNX1	P27361	MAPK3	S212	P216H	216	Missense	distal	4	no	17.427	17.335	EPSD	TCGA	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q01196	RUNX1	P27361	MAPK3	T219	P216H	216	Missense	distal	-3	no	13.849	13.809	EPSD	TCGA	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q01196	RUNX1	P27361	MAPK3	S435	A440T	440	Missense	distal	5	no	19.908	20.028	EPSD	TCGA;ICGC;COSMIC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q01196	RUNX1	P27361	MAPK3	S442	A440T	440	Missense	proximal	-2	no	8.749	10.114	EPSD	TCGA;ICGC;COSMIC	9.358	Gain
CMGC_MAPK_ERK1_MAPK3_ST	Q01860	POU5F1	P27361	MAPK3	S111	P112R	112	Missense	proximal	1	no	15.165	5.664	PhosphoSitePlus	TCGA;ICGC;COSMIC	9.358	Loss
CMGC_MAPK_ERK1_MAPK3_ST	Q01860	POU5F1	P27361	MAPK3	S111	S111F	111	Missense	central	0	yes	15.165	0.000	PhosphoSitePlus	TCGA;ICGC;COSMIC	9.358	Loss
CMGC_MAPK_ERK1_MAPK3_ST	Q01860	POU5F1	P27361	MAPK3	S111	P112L	112	Missense	proximal	1	no	15.165	6.127	PhosphoSitePlus	TCGA;ICGC;COSMIC	9.358	Loss
CMGC_MAPK_ERK1_MAPK3_ST	Q01860	POU5F1	P27361	MAPK3	S111	V117I	117	Missense	distal	6	no	15.165	15.034	PhosphoSitePlus	TCGA;ICGC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q01860	POU5F1	P27361	MAPK3	T118	P112R	112	Missense	distal	-6	no	16.550	16.474	EPSD	TCGA;ICGC;COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q01860	POU5F1	P27361	MAPK3	T118	S111F	111	Missense	distal	-7	no	16.550	16.769	EPSD	TCGA;ICGC;COSMIC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q01860	POU5F1	P27361	MAPK3	T118	P112L	112	Missense	distal	-6	no	16.550	16.303	EPSD	TCGA;ICGC;COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q01860	POU5F1	P27361	MAPK3	T118	V117I	117	Missense	proximal	-1	no	16.550	16.502	EPSD	TCGA;ICGC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q01860	POU5F1	P27361	MAPK3	T118	P119H	119	Missense	proximal	1	no	16.550	8.794	EPSD	TCGA;ICGC;COSMIC	9.358	Loss
CMGC_MAPK_ERK1_MAPK3_ST	P49841	GSK3B	P27361	MAPK3	S21	Q19R	19	Missense	proximal	-2	no	9.036	9.400	EPSD	TCGA	9.358	Gain
CMGC_MAPK_ERK1_MAPK3_ST	P49841	GSK3B	P27361	MAPK3	T43	D49N	49	Missense	distal	6	no	15.457	15.405	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P49841	GSK3B	P27361	MAPK3	S66	T59I	59	Missense	distal	-7	no	9.307	9.422	EPSD	TCGA;ICGC;COSMIC	9.358	Gain
CMGC_MAPK_ERK1_MAPK3_ST	Q16584	MAP3K11	P27361	MAPK3	S11	S11N	11	Missense	central	0	yes	16.073	0.000	EPSD	TCGA;ICGC;COSMIC	9.358	Loss
CMGC_MAPK_ERK1_MAPK3_ST	Q16584	MAP3K11	P27361	MAPK3	S15	S11N	11	Missense	distal	-4	no	11.096	11.035	EPSD	TCGA;ICGC;COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q16584	MAP3K11	P27361	MAPK3	S35	G40S	40	Missense	distal	5	no	17.686	17.750	EPSD	TCGA;ICGC;COSMIC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q16584	MAP3K11	P27361	MAPK3	S507	R514K	514	Missense	distal	7	no	15.795	15.800	EPSD	TCGA;ICGC;COSMIC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q16584	MAP3K11	P27361	MAPK3	S524	E518K	518	Missense	distal	-6	no	15.473	15.331	EPSD	TCGA;ICGC;COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q16584	MAP3K11	P27361	MAPK3	S524	P525L	525	Missense	proximal	1	no	15.473	6.435	EPSD	TCGA;ICGC;COSMIC	9.358	Loss
CMGC_MAPK_ERK1_MAPK3_ST	Q16584	MAP3K11	P27361	MAPK3	S524	G520R	520	Missense	distal	-4	no	15.473	15.434	EPSD	TCGA;ICGC;COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q16584	MAP3K11	P27361	MAPK3	S524	R529W	529	Missense	distal	5	no	15.473	15.005	EPSD	TCGA;COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q16584	MAP3K11	P27361	MAPK3	S524	R531Q	531	Missense	distal	7	no	15.473	15.503	EPSD	TCGA;ICGC;COSMIC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q16584	MAP3K11	P27361	MAPK3	S548	R550Q	550	Missense	proximal	2	no	14.117	14.108	EPSD	TCGA	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q16584	MAP3K11	P27361	MAPK3	S548	S548F	548	Missense	central	0	yes	14.117	0.000	EPSD	TCGA;ICGC;COSMIC	9.358	Loss
CMGC_MAPK_ERK1_MAPK3_ST	Q16584	MAP3K11	P27361	MAPK3	S569	S570F	570	Missense	proximal	1	no	8.369	11.209	EPSD	TCGA;ICGC;COSMIC	9.358	Gain
CMGC_MAPK_ERK1_MAPK3_ST	Q16584	MAP3K11	P27361	MAPK3	S570	Q577H	577	Missense	distal	7	no	17.779	17.717	EPSD	TCGA;COSMIC;GDSC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q16584	MAP3K11	P27361	MAPK3	S570	S570F	570	Missense	central	0	yes	17.779	0.000	EPSD	TCGA;ICGC;COSMIC	9.358	Loss
CMGC_MAPK_ERK1_MAPK3_ST	Q16584	MAP3K11	P27361	MAPK3	S674	R669H	669	Missense	distal	-5	no	16.454	16.464	EPSD	TCGA;ICGC;COSMIC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q16584	MAP3K11	P27361	MAPK3	T677	A684T	684	Missense	distal	7	no	17.924	17.697	EPSD	TCGA;ICGC;COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q16584	MAP3K11	P27361	MAPK3	T680	P687L	687	Missense	distal	7	no	15.975	16.167	EPSD	TCGA;ICGC;COSMIC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q16584	MAP3K11	P27361	MAPK3	T680	A684T	684	Missense	distal	4	no	15.975	16.193	EPSD	TCGA;ICGC;COSMIC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q16584	MAP3K11	P27361	MAPK3	T682	P687L	687	Missense	distal	5	no	15.983	15.755	EPSD	TCGA;ICGC;COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q16584	MAP3K11	P27361	MAPK3	T682	T688I	688	Missense	distal	6	no	15.983	15.569	EPSD	TCGA;COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q16584	MAP3K11	P27361	MAPK3	T682	A684T	684	Missense	proximal	2	no	15.983	16.011	EPSD	TCGA;ICGC;COSMIC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q16584	MAP3K11	P27361	MAPK3	S693	P687L	687	Missense	distal	-6	no	17.772	17.524	EPSD	TCGA;ICGC;COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q16584	MAP3K11	P27361	MAPK3	S693	T688I	688	Missense	distal	-5	no	17.772	17.693	EPSD	TCGA;COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q16584	MAP3K11	P27361	MAPK3	T702	P706L	706	Missense	distal	4	no	14.155	14.001	EPSD	TCGA;ICGC;COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q16584	MAP3K11	P27361	MAPK3	T702	D704N	704	Missense	proximal	2	no	14.155	14.149	EPSD	TCGA	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q16584	MAP3K11	P27361	MAPK3	S705	P706L	706	Missense	proximal	1	no	17.626	8.588	PhosphoSitePlus;EPSD	TCGA;ICGC;COSMIC	9.358	Loss
CMGC_MAPK_ERK1_MAPK3_ST	Q16584	MAP3K11	P27361	MAPK3	S705	D704N	704	Missense	proximal	-1	no	17.626	17.624	PhosphoSitePlus;EPSD	TCGA	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q16584	MAP3K11	P27361	MAPK3	T708	P706L	706	Missense	proximal	-2	no	15.274	13.890	EPSD	TCGA;ICGC;COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q16584	MAP3K11	P27361	MAPK3	T708	D704N	704	Missense	distal	-4	no	15.274	15.248	EPSD	TCGA	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q16584	MAP3K11	P27361	MAPK3	S740	R747H	747	Missense	distal	7	no	17.364	17.332	EPSD	TCGA;COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q16584	MAP3K11	P27361	MAPK3	S740	P743L	743	Missense	distal	3	no	17.364	17.328	EPSD	TCGA;COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q16584	MAP3K11	P27361	MAPK3	T752	R747H	747	Missense	distal	-5	no	18.143	18.153	EPSD	TCGA;COSMIC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q16584	MAP3K11	P27361	MAPK3	T752	R757H	757	Missense	distal	5	no	18.143	18.179	EPSD	TCGA;COSMIC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q16584	MAP3K11	P27361	MAPK3	T755	R757H	757	Missense	proximal	2	no	15.926	15.923	EPSD	TCGA;COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q16584	MAP3K11	P27361	MAPK3	S758	R757H	757	Missense	proximal	-1	no	16.235	16.238	EPSD;PhosphoSitePlus	TCGA;COSMIC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q16584	MAP3K11	P27361	MAPK3	S770	R773C	773	Missense	distal	3	no	14.890	14.827	EPSD	TCGA;ICGC;COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q16584	MAP3K11	P27361	MAPK3	S770	R768Q	768	Missense	proximal	-2	no	14.890	14.527	EPSD	TCGA	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q16584	MAP3K11	P27361	MAPK3	S770	S770L	770	Missense	central	0	yes	14.890	0.000	EPSD	TCGA;COSMIC	9.358	Loss
CMGC_MAPK_ERK1_MAPK3_ST	Q16584	MAP3K11	P27361	MAPK3	S770	P771L	771	Missense	proximal	1	no	14.890	5.852	EPSD	TCGA;COSMIC	9.358	Loss
CMGC_MAPK_ERK1_MAPK3_ST	Q16584	MAP3K11	P27361	MAPK3	S780	A784V	784	Missense	distal	4	no	11.080	11.188	EPSD	TCGA;ICGC;COSMIC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q16584	MAP3K11	P27361	MAPK3	S780	R773C	773	Missense	distal	-7	no	11.080	11.266	EPSD	TCGA;ICGC;COSMIC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q16584	MAP3K11	P27361	MAPK3	S780	R787L	787	Missense	distal	7	no	11.080	11.180	EPSD	TCGA;COSMIC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q16584	MAP3K11	P27361	MAPK3	S780	P778S	778	Missense	proximal	-2	no	11.080	10.004	EPSD	TCGA;ICGC;COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q16584	MAP3K11	P27361	MAPK3	S789	A784V	784	Missense	distal	-5	no	16.353	16.376	EPSD	TCGA;ICGC;COSMIC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q16584	MAP3K11	P27361	MAPK3	S789	R787L	787	Missense	proximal	-2	no	16.353	16.368	EPSD	TCGA;COSMIC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q16584	MAP3K11	P27361	MAPK3	S789	P790L	790	Missense	proximal	1	no	16.353	7.315	EPSD	TCGA;COSMIC	9.358	Loss
CMGC_MAPK_ERK1_MAPK3_ST	Q16584	MAP3K11	P27361	MAPK3	S789	P792S	792	Missense	distal	3	no	16.353	16.348	EPSD	TCGA	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q16584	MAP3K11	P27361	MAPK3	S793	R787L	787	Missense	distal	-6	no	17.525	17.353	EPSD	TCGA;COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q16584	MAP3K11	P27361	MAPK3	S793	P790L	790	Missense	distal	-3	no	17.525	17.440	EPSD	TCGA;COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q16584	MAP3K11	P27361	MAPK3	S793	R800Q	800	Missense	distal	7	no	17.525	17.554	EPSD	TCGA;COSMIC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q16584	MAP3K11	P27361	MAPK3	S793	P792S	792	Missense	proximal	-1	no	17.525	17.519	EPSD	TCGA	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q16584	MAP3K11	P27361	MAPK3	S815	D814E	814	Missense	proximal	-1	no	11.816	11.837	EPSD	TCGA;ICGC;COSMIC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q96FF9	CDCA5	P27361	MAPK3	S21	S15C	15	Missense	distal	-6	no	17.568	17.009	EPSD	TCGA;ICGC;COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q96FF9	CDCA5	P27361	MAPK3	S29	S33L	33	Missense	distal	4	no	12.561	12.358	EPSD	TCGA;ICGC;COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q96FF9	CDCA5	P27361	MAPK3	S29	S29F	29	Missense	central	0	yes	12.561	0.000	EPSD	TCGA;ICGC;COSMIC	9.358	Loss
CMGC_MAPK_ERK1_MAPK3_ST	Q96FF9	CDCA5	P27361	MAPK3	S75	S75L	75	Missense	central	0	yes	16.138	0.000	EPSD	TCGA;ICGC;COSMIC	9.358	Loss
CMGC_MAPK_ERK1_MAPK3_ST	Q96FF9	CDCA5	P27361	MAPK3	S79	S75L	75	Missense	distal	-4	no	14.812	14.672	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q96FF9	CDCA5	P27361	MAPK3	T111	P116H	116	Missense	distal	5	no	16.827	16.762	EPSD	TCGA;ICGC;COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q96FF9	CDCA5	P27361	MAPK3	T111	V108I	108	Missense	distal	-3	no	16.827	16.788	EPSD	TCGA;ICGC;COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q96FF9	CDCA5	P27361	MAPK3	S114	P116H	116	Missense	proximal	2	no	9.766	9.753	EPSD	TCGA;ICGC;COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q96FF9	CDCA5	P27361	MAPK3	S114	V108I	108	Missense	distal	-6	no	9.766	9.698	EPSD	TCGA;ICGC;COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q96FF9	CDCA5	P27361	MAPK3	T115	P116H	116	Missense	proximal	1	no	15.340	7.584	EPSD	TCGA;ICGC;COSMIC	9.358	Loss
CMGC_MAPK_ERK1_MAPK3_ST	Q96FF9	CDCA5	P27361	MAPK3	T115	V108I	108	Missense	distal	-7	no	15.340	15.382	EPSD	TCGA;ICGC;COSMIC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q96FF9	CDCA5	P27361	MAPK3	T159	S156C	156	Missense	distal	-3	no	14.467	14.289	EPSD	TCGA;ICGC;COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q96FF9	CDCA5	P27361	MAPK3	T159	S158F	158	Missense	proximal	-1	no	14.467	14.263	EPSD	TCGA;ICGC;COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q96FF9	CDCA5	P27361	MAPK3	S209	G207V	207	Missense	proximal	-2	no	14.429	14.891	PhosphoSitePlus;EPSD	TCGA;ICGC;COSMIC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q96FF9	CDCA5	P27361	MAPK3	S209	P212L	212	Missense	distal	3	no	14.429	14.392	PhosphoSitePlus;EPSD	TCGA;ICGC;COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q96FF9	CDCA5	P27361	MAPK3	S209	P211L	211	Missense	proximal	2	no	14.429	14.407	PhosphoSitePlus;EPSD	TCGA;ICGC;COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q96FF9	CDCA5	P27361	MAPK3	S209	E213D	213	Missense	distal	4	no	14.429	14.409	PhosphoSitePlus;EPSD	TCGA;ICGC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q8IZP0	ABI1	P27361	MAPK3	S183	S183G	183	Missense	central	0	yes	18.665	0.000	EPSD;PhosphoSitePlus	TCGA;COSMIC	9.358	Loss
CMGC_MAPK_ERK1_MAPK3_ST	Q8IZP0	ABI1	P27361	MAPK3	S183	P177L	177	Missense	distal	-6	no	18.665	18.418	EPSD;PhosphoSitePlus	TCGA;COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q8IZP0	ABI1	P27361	MAPK3	S183	P181L	181	Missense	proximal	-2	no	18.665	17.281	EPSD;PhosphoSitePlus	TCGA	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q8IZP0	ABI1	P27361	MAPK3	T196	P197H	197	Missense	proximal	1	no	14.732	6.976	EPSD	TCGA;COSMIC	9.358	Loss
CMGC_MAPK_ERK1_MAPK3_ST	Q8IZP0	ABI1	P27361	MAPK3	T238	S240C	240	Missense	proximal	2	no	10.382	10.321	EPSD	TCGA;COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q8IZP0	ABI1	P27361	MAPK3	S248	R249Q	249	Missense	proximal	1	no	8.656	10.213	EPSD	TCGA	9.358	Gain
CMGC_MAPK_ERK1_MAPK3_ST	Q8IZP0	ABI1	P27361	MAPK3	T336	V339M	339	Missense	distal	3	no	15.296	15.271	EPSD	TCGA;COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q8IZP0	ABI1	P27361	MAPK3	T336	T340I	340	Missense	distal	4	no	15.296	15.068	EPSD	TCGA;ICGC;COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q8IZP0	ABI1	P27361	MAPK3	T336	R335Q	335	Missense	proximal	-1	no	15.296	15.257	EPSD	TCGA;COSMIC;CCLE	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q8IZP0	ABI1	P27361	MAPK3	S392	Q386R	386	Missense	distal	-6	no	14.393	14.383	EPSD;PhosphoSitePlus	TCGA;COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q8IZP0	ABI1	P27361	MAPK3	S392	P396L	396	Missense	distal	4	no	14.393	14.238	EPSD;PhosphoSitePlus	TCGA;COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q8IZP0	ABI1	P27361	MAPK3	T394	P396L	396	Missense	proximal	2	no	14.735	14.713	EPSD;PhosphoSitePlus	TCGA;COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q8IZP0	ABI1	P27361	MAPK3	S410	P405L	405	Missense	distal	-5	no	16.907	16.853	PhosphoSitePlus;EPSD	TCGA	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q8IZP0	ABI1	P27361	MAPK3	S466	D463N	463	Missense	distal	-3	no	9.532	9.511	EPSD	TCGA;COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P35658	NUP214	P27361	MAPK3	S30	P35L	35	Missense	distal	5	no	15.068	14.840	EPSD	TCGA;ICGC;COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P35658	NUP214	P27361	MAPK3	S30	D29E	29	Missense	proximal	-1	no	15.068	15.090	EPSD	TCGA;ICGC;COSMIC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P35658	NUP214	P27361	MAPK3	T416	E418Q	418	Missense	proximal	2	no	14.782	14.768	EPSD	TCGA;ICGC;COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P35658	NUP214	P27361	MAPK3	S430	S433R	433	Missense	distal	3	no	18.796	18.774	EPSD	TCGA;ICGC;COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P35658	NUP214	P27361	MAPK3	S433	S433R	433	Missense	central	0	yes	9.866	0.000	EPSD	TCGA;ICGC;COSMIC	9.358	Loss
CMGC_MAPK_ERK1_MAPK3_ST	P35658	NUP214	P27361	MAPK3	T434	S433R	433	Missense	proximal	-1	no	14.751	14.710	EPSD	TCGA;ICGC;COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P35658	NUP214	P27361	MAPK3	T437	S433R	433	Missense	distal	-4	no	16.689	16.612	EPSD	TCGA;ICGC;COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P35658	NUP214	P27361	MAPK3	T437	P444T	444	Missense	distal	7	no	16.689	16.730	EPSD	TCGA;ICGC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P35658	NUP214	P27361	MAPK3	S440	S433R	433	Missense	distal	-7	no	9.966	10.049	EPSD	TCGA;ICGC;COSMIC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P35658	NUP214	P27361	MAPK3	S440	P444T	444	Missense	distal	4	no	9.966	9.902	EPSD	TCGA;ICGC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P35658	NUP214	P27361	MAPK3	S462	A465S	465	Missense	distal	3	no	16.511	16.555	EPSD	TCGA;ICGC;COSMIC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P35658	NUP214	P27361	MAPK3	S462	S462L	462	Missense	central	0	yes	16.511	0.000	EPSD	TCGA;ICGC;COSMIC	9.358	Loss
CMGC_MAPK_ERK1_MAPK3_ST	P35658	NUP214	P27361	MAPK3	S483	F484I	484	Missense	proximal	1	no	10.983	7.690	EPSD	TCGA;ICGC;COSMIC	9.358	Loss
CMGC_MAPK_ERK1_MAPK3_ST	P35658	NUP214	P27361	MAPK3	S483	G485R	485	Missense	proximal	2	no	10.983	10.988	EPSD	TCGA;ICGC;COSMIC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P35658	NUP214	P27361	MAPK3	S501	S506F	506	Missense	distal	5	no	12.628	12.203	EPSD	TCGA;ICGC;COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P35658	NUP214	P27361	MAPK3	S501	P500S	500	Missense	proximal	-1	no	12.628	12.622	EPSD	TCGA;ICGC;COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P35658	NUP214	P27361	MAPK3	S501	D507N	507	Missense	distal	6	no	12.628	12.575	EPSD	TCGA;ICGC;COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P35658	NUP214	P27361	MAPK3	T519	S521Y	521	Missense	proximal	2	no	11.920	11.898	EPSD	TCGA;ICGC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P35658	NUP214	P27361	MAPK3	T519	F520L	520	Missense	proximal	1	no	11.920	9.096	EPSD	TCGA;ICGC;COSMIC	9.358	Loss
CMGC_MAPK_ERK1_MAPK3_ST	P35658	NUP214	P27361	MAPK3	T519	S526F	526	Missense	distal	7	no	11.920	12.411	EPSD	TCGA;ICGC;COSMIC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P35658	NUP214	P27361	MAPK3	T519	F522V	522	Missense	distal	3	no	11.920	11.947	EPSD	TCGA;ICGC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P35658	NUP214	P27361	MAPK3	T533	L530V	530	Missense	distal	-3	no	14.038	14.041	EPSD	TCGA;ICGC;COSMIC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P35658	NUP214	P27361	MAPK3	T533	S526F	526	Missense	distal	-7	no	14.038	14.257	EPSD	TCGA;ICGC;COSMIC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P35658	NUP214	P27361	MAPK3	T533	S529F	529	Missense	distal	-4	no	14.038	13.849	EPSD	TCGA;ICGC;COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P35658	NUP214	P27361	MAPK3	S537	L530V	530	Missense	distal	-7	no	15.176	15.181	EPSD	TCGA;ICGC;COSMIC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P35658	NUP214	P27361	MAPK3	S547	G549V	549	Missense	proximal	2	no	12.827	12.819	EPSD	TCGA;ICGC;COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P35658	NUP214	P27361	MAPK3	T560	P563S	563	Missense	distal	3	no	16.717	16.712	EPSD	TCGA;ICGC;COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P35658	NUP214	P27361	MAPK3	T580	S581P	581	Missense	proximal	1	no	6.266	15.320	EPSD	TCGA;ICGC;COSMIC	9.358	Gain
CMGC_MAPK_ERK1_MAPK3_ST	P35658	NUP214	P27361	MAPK3	T598	T592A	592	Missense	distal	-6	no	15.639	15.491	EPSD	TCGA;ICGC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P35658	NUP214	P27361	MAPK3	S610	S616Y	616	Missense	distal	6	no	17.882	17.500	EPSD	TCGA;ICGC;COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P35658	NUP214	P27361	MAPK3	S610	P607H	607	Missense	distal	-3	no	17.882	17.842	EPSD	TCGA;ICGC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P35658	NUP214	P27361	MAPK3	S646	S642L	642	Missense	distal	-4	no	15.451	15.311	EPSD	TCGA;ICGC;COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P35658	NUP214	P27361	MAPK3	S678	S678C	678	Missense	central	0	yes	16.323	0.000	EPSD	TCGA;COSMIC	9.358	Loss
CMGC_MAPK_ERK1_MAPK3_ST	P35658	NUP214	P27361	MAPK3	S678	P679S	679	Missense	proximal	1	no	16.323	7.270	EPSD	TCGA;COSMIC	9.358	Loss
CMGC_MAPK_ERK1_MAPK3_ST	P35658	NUP214	P27361	MAPK3	T1021	R1020C	1020	Missense	proximal	-1	no	14.464	14.279	EPSD	TCGA;COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P35658	NUP214	P27361	MAPK3	T1021	S1023F	1023	Missense	proximal	2	no	14.464	14.414	EPSD	TCGA;COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P35658	NUP214	P27361	MAPK3	T1021	S1027R	1027	Missense	distal	6	no	14.464	14.223	EPSD	TCGA;COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P35658	NUP214	P27361	MAPK3	S1081	S1087L	1087	Missense	distal	6	no	14.585	14.228	EPSD	TCGA;COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P35658	NUP214	P27361	MAPK3	T1134	P1132L	1132	Missense	proximal	-2	no	15.218	13.834	EPSD	TCGA;COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P35658	NUP214	P27361	MAPK3	T1134	K1129N	1129	Missense	distal	-5	no	15.218	15.224	EPSD	TCGA;COSMIC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P35658	NUP214	P27361	MAPK3	T1134	L1128F	1128	Missense	distal	-6	no	15.218	15.083	EPSD	TCGA;COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P35658	NUP214	P27361	MAPK3	T1134	T1134A	1134	Missense	central	0	yes	15.218	0.000	EPSD	TCGA;COSMIC	9.358	Loss
CMGC_MAPK_ERK1_MAPK3_ST	P35658	NUP214	P27361	MAPK3	S1136	P1132L	1132	Missense	distal	-4	no	9.690	9.578	EPSD	TCGA;COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P35658	NUP214	P27361	MAPK3	S1136	K1129N	1129	Missense	distal	-7	no	9.690	9.674	EPSD	TCGA;COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P35658	NUP214	P27361	MAPK3	S1136	T1134A	1134	Missense	proximal	-2	no	9.690	8.325	EPSD	TCGA;COSMIC	9.358	Loss
CMGC_MAPK_ERK1_MAPK3_ST	P35658	NUP214	P27361	MAPK3	T1150	A1148T	1148	Missense	proximal	-2	no	15.675	17.040	EPSD	TCGA	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P35658	NUP214	P27361	MAPK3	T1150	T1150K	1150	Missense	central	0	yes	15.675	0.000	EPSD	TCGA;COSMIC	9.358	Loss
CMGC_MAPK_ERK1_MAPK3_ST	P35658	NUP214	P27361	MAPK3	T1156	T1150K	1150	Missense	distal	-6	no	14.200	14.210	EPSD	TCGA;COSMIC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P35658	NUP214	P27361	MAPK3	T1178	K1173E	1173	Missense	distal	-5	no	12.304	12.316	EPSD	TCGA;COSMIC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P35658	NUP214	P27361	MAPK3	T1178	S1175A	1175	Missense	distal	-3	no	12.304	12.212	EPSD	TCGA	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P35658	NUP214	P27361	MAPK3	T1203	S1207Y	1207	Missense	distal	4	no	16.186	15.970	EPSD	TCGA	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P35658	NUP214	P27361	MAPK3	S1215	S1219L	1219	Missense	distal	4	no	11.303	11.100	EPSD	TCGA;COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P35658	NUP214	P27361	MAPK3	S1215	S1215L	1215	Missense	central	0	yes	11.303	0.000	EPSD	TCGA;COSMIC	9.358	Loss
CMGC_MAPK_ERK1_MAPK3_ST	P35658	NUP214	P27361	MAPK3	S1217	S1219L	1219	Missense	proximal	2	no	17.250	17.227	EPSD	TCGA;COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P35658	NUP214	P27361	MAPK3	S1217	S1215L	1215	Missense	proximal	-2	no	17.250	16.942	EPSD	TCGA;COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P35658	NUP214	P27361	MAPK3	T1229	I1227L	1227	Missense	proximal	-2	no	14.531	14.985	EPSD	TCGA;COSMIC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P35658	NUP214	P27361	MAPK3	T1229	P1232L	1232	Missense	distal	3	no	14.531	14.494	EPSD	TCGA	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P35658	NUP214	P27361	MAPK3	T1231	I1227L	1227	Missense	distal	-4	no	15.182	15.201	EPSD	TCGA;COSMIC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P35658	NUP214	P27361	MAPK3	T1231	P1232L	1232	Missense	proximal	1	no	15.182	6.144	EPSD	TCGA	9.358	Loss
CMGC_MAPK_ERK1_MAPK3_ST	P35658	NUP214	P27361	MAPK3	S1272	P1274L	1274	Missense	proximal	2	no	16.201	16.180	EPSD	TCGA;COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P35658	NUP214	P27361	MAPK3	S1272	E1266G	1266	Missense	distal	-6	no	16.201	16.155	EPSD	TCGA;COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P35658	NUP214	P27361	MAPK3	T1284	G1286E	1286	Missense	proximal	2	no	14.715	14.723	EPSD	TCGA;COSMIC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P35658	NUP214	P27361	MAPK3	S1307	S1307F	1307	Missense	central	0	yes	9.475	0.000	EPSD	TCGA;ICGC;COSMIC	9.358	Loss
CMGC_MAPK_ERK1_MAPK3_ST	P35658	NUP214	P27361	MAPK3	S1307	L1310M	1310	Missense	distal	3	no	9.475	9.445	EPSD	TCGA;ICGC;COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P35658	NUP214	P27361	MAPK3	T1312	S1307F	1307	Missense	distal	-5	no	14.510	14.376	EPSD	TCGA;ICGC;COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P35658	NUP214	P27361	MAPK3	T1312	E1319K	1319	Missense	distal	7	no	14.510	14.581	EPSD	TCGA;COSMIC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P35658	NUP214	P27361	MAPK3	T1312	L1310M	1310	Missense	proximal	-2	no	14.510	13.140	EPSD	TCGA;ICGC;COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P35658	NUP214	P27361	MAPK3	T1946	G1950E	1950	Missense	distal	4	no	10.439	10.499	EPSD	TCGA;COSMIC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P35658	NUP214	P27361	MAPK3	T1946	G1952E	1952	Missense	distal	6	no	10.439	10.539	EPSD	TCGA;ICGC;COSMIC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P35658	NUP214	P27361	MAPK3	S2002	G2009S	2009	Missense	distal	7	no	16.922	16.783	EPSD	TCGA;COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P35658	NUP214	P27361	MAPK3	S2002	P2003H	2003	Missense	proximal	1	no	16.922	9.166	EPSD	TCGA	9.358	Loss
CMGC_MAPK_ERK1_MAPK3_ST	Q15672	TWIST1	P27361	MAPK3	S99	G97S	97	Missense	proximal	-2	no	17.724	18.764	EPSD	TCGA;ICGC;COSMIC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q15672	TWIST1	P27361	MAPK3	S102	G97S	97	Missense	distal	-5	no	10.246	10.289	EPSD	TCGA;ICGC;COSMIC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P28562	DUSP1	P27361	MAPK3	T141	S137R	137	Missense	distal	-4	no	12.707	12.630	EPSD	TCGA;ICGC;COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P28562	DUSP1	P27361	MAPK3	S323	P324L	324	Missense	proximal	1	no	14.525	5.487	EPSD	TCGA;ICGC;COSMIC	9.358	Loss
CMGC_MAPK_ERK1_MAPK3_ST	P28562	DUSP1	P27361	MAPK3	S323	A325T	325	Missense	proximal	2	no	14.525	14.553	EPSD	TCGA;ICGC;COSMIC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P28562	DUSP1	P27361	MAPK3	S323	S318L	318	Missense	distal	-5	no	14.525	14.466	EPSD	TCGA;ICGC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P28562	DUSP1	P27361	MAPK3	S359	A353V	353	Missense	distal	-6	no	18.543	18.530	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC;GDSC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P28562	DUSP1	P27361	MAPK3	S359	L354P	354	Missense	distal	-5	no	18.543	18.598	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q92974	ARHGEF2	P27361	MAPK3	S163	R168C	168	Missense	distal	5	no	16.999	16.620	EPSD	TCGA;ICGC;COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q92974	ARHGEF2	P27361	MAPK3	S172	R168C	168	Missense	distal	-4	no	9.741	9.580	EPSD	TCGA;ICGC;COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q92974	ARHGEF2	P27361	MAPK3	S172	S174F	174	Missense	proximal	2	no	9.741	9.690	EPSD	TCGA;COSMIC;CCLE	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q92974	ARHGEF2	P27361	MAPK3	T455	R452W	452	Missense	distal	-3	no	12.419	12.252	EPSD	TCGA;COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q92974	ARHGEF2	P27361	MAPK3	T455	P456S	456	Missense	proximal	1	no	12.419	3.366	EPSD	TCGA;COSMIC	9.358	Loss
CMGC_MAPK_ERK1_MAPK3_ST	Q92974	ARHGEF2	P27361	MAPK3	T455	P451T	451	Missense	distal	-4	no	12.419	12.388	EPSD	TCGA;COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q92974	ARHGEF2	P27361	MAPK3	S648	R650C	650	Missense	proximal	2	no	17.806	17.757	EPSD	TCGA;COSMIC;CCLE	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q92974	ARHGEF2	P27361	MAPK3	S648	R653Q	653	Missense	distal	5	no	17.806	17.804	EPSD	TCGA;COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q92974	ARHGEF2	P27361	MAPK3	T679	V674M	674	Missense	distal	-5	no	15.038	14.995	EPSD;PhosphoSitePlus	TCGA	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q92974	ARHGEF2	P27361	MAPK3	S696	P697L	697	Missense	proximal	1	no	15.941	6.903	EPSD	TCGA;COSMIC	9.358	Loss
CMGC_MAPK_ERK1_MAPK3_ST	Q92974	ARHGEF2	P27361	MAPK3	S696	P697A	697	Missense	proximal	1	no	15.941	6.701	EPSD	TCGA;COSMIC	9.358	Loss
CMGC_MAPK_ERK1_MAPK3_ST	Q92974	ARHGEF2	P27361	MAPK3	S696	T695M	695	Missense	proximal	-1	no	15.941	15.816	EPSD	TCGA;COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q92974	ARHGEF2	P27361	MAPK3	S733	P734L	734	Missense	proximal	1	no	18.244	9.206	EPSD	TCGA	9.358	Loss
CMGC_MAPK_ERK1_MAPK3_ST	Q92974	ARHGEF2	P27361	MAPK3	S733	A738V	738	Missense	distal	5	no	18.244	18.232	EPSD	TCGA;COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q92974	ARHGEF2	P27361	MAPK3	S932	R936W	936	Missense	distal	4	no	14.564	14.096	EPSD	TCGA;COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q92974	ARHGEF2	P27361	MAPK3	S932	P933L	933	Missense	proximal	1	no	14.564	5.526	EPSD	TCGA;COSMIC	9.358	Loss
CMGC_MAPK_ERK1_MAPK3_ST	Q92974	ARHGEF2	P27361	MAPK3	S956	S953R	953	Missense	distal	-3	no	16.965	16.927	EPSD	TCGA;COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q92974	ARHGEF2	P27361	MAPK3	S956	R954H	954	Missense	proximal	-2	no	16.965	17.137	EPSD	TCGA;COSMIC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q92974	ARHGEF2	P27361	MAPK3	S956	R954C	954	Missense	proximal	-2	no	16.965	14.849	EPSD	TCGA;COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q92974	ARHGEF2	P27361	MAPK3	S956	S960N	960	Missense	distal	4	no	16.965	16.818	EPSD	TCGA;COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q92974	ARHGEF2	P27361	MAPK3	S960	R966T	966	Missense	distal	6	no	20.015	20.102	EPSD	TCGA;COSMIC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q92974	ARHGEF2	P27361	MAPK3	S960	S953R	953	Missense	distal	-7	no	20.015	20.098	EPSD	TCGA;COSMIC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q92974	ARHGEF2	P27361	MAPK3	S960	R954H	954	Missense	distal	-6	no	20.015	20.011	EPSD	TCGA;COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q92974	ARHGEF2	P27361	MAPK3	S960	R954C	954	Missense	distal	-6	no	20.015	19.616	EPSD	TCGA;COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q92974	ARHGEF2	P27361	MAPK3	S960	S960N	960	Missense	central	0	yes	20.015	0.000	EPSD	TCGA;COSMIC	9.358	Loss
CMGC_MAPK_ERK1_MAPK3_ST	Q15796	SMAD2	P27361	MAPK3	T172	P176R	176	Missense	distal	4	no	13.836	13.738	EPSD	TCGA	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q15796	SMAD2	P27361	MAPK3	S245	S250F	250	Missense	distal	5	no	20.102	19.677	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q15796	SMAD2	P27361	MAPK3	S250	S250F	250	Missense	central	0	yes	17.689	0.000	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	9.358	Loss
CMGC_MAPK_ERK1_MAPK3_ST	Q15796	SMAD2	P27361	MAPK3	S255	D262Y	262	Missense	distal	7	no	18.277	18.426	PhosphoSitePlus;EPSD	TCGA;ICGC;COSMIC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q15796	SMAD2	P27361	MAPK3	S255	S250F	250	Missense	distal	-5	no	18.277	18.143	PhosphoSitePlus;EPSD	TCGA;ICGC;COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q15796	SMAD2	P27361	MAPK3	S417	G421W	421	Missense	distal	4	no	9.485	9.031	EPSD	TCGA;ICGC;COSMIC	9.358	Loss
CMGC_MAPK_ERK1_MAPK3_ST	Q15796	SMAD2	P27361	MAPK3	S417	G421A	421	Missense	distal	4	no	9.485	9.314	EPSD	TCGA;ICGC;COSMIC	9.358	Loss
CMGC_MAPK_ERK1_MAPK3_ST	Q15796	SMAD2	P27361	MAPK3	S417	S417R	417	Missense	central	0	yes	9.485	0.000	EPSD	TCGA;ICGC	9.358	Loss
CMGC_MAPK_ERK1_MAPK3_ST	Q15796	SMAD2	P27361	MAPK3	T454	K451E	451	Missense	distal	-3	no	9.423	9.455	EPSD	TCGA;ICGC;COSMIC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q15796	SMAD2	P27361	MAPK3	T454	D450E	450	Missense	distal	-4	no	9.423	9.434	EPSD	TCGA;ICGC;COSMIC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q15796	SMAD2	P27361	MAPK3	T454	D450N	450	Missense	distal	-4	no	9.423	9.397	EPSD	TCGA;ICGC;COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q15796	SMAD2	P27361	MAPK3	T454	G457A	457	Missense	distal	3	no	9.423	9.395	EPSD	TCGA;ICGC;COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q15796	SMAD2	P27361	MAPK3	S458	K451E	451	Missense	distal	-7	no	15.165	15.114	EPSD	TCGA;ICGC;COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q15796	SMAD2	P27361	MAPK3	S458	G457A	457	Missense	proximal	-1	no	15.165	15.098	EPSD	TCGA;ICGC;COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q15796	SMAD2	P27361	MAPK3	S464	G457A	457	Missense	distal	-7	no	9.782	9.894	EPSD	TCGA;ICGC;COSMIC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P16144	ITGB4	P27361	MAPK3	S7	S7R	7	Missense	central	0	yes	14.938	0.000	EPSD	TCGA;ICGC;COSMIC	9.358	Loss
CMGC_MAPK_ERK1_MAPK3_ST	P16144	ITGB4	P27361	MAPK3	S7	R5H	5	Missense	proximal	-2	no	14.938	15.111	EPSD	TCGA;ICGC;COSMIC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P16144	ITGB4	P27361	MAPK3	S19	L17F	17	Missense	proximal	-2	no	10.849	9.857	EPSD	TCGA;ICGC;COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P16144	ITGB4	P27361	MAPK3	S128	P125Q	125	Missense	distal	-3	no	15.588	15.534	EPSD	TCGA;ICGC;COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P16144	ITGB4	P27361	MAPK3	S128	E124Q	124	Missense	distal	-4	no	15.588	15.545	EPSD	TCGA;ICGC;COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P16144	ITGB4	P27361	MAPK3	S202	D198E	198	Missense	distal	-4	no	12.834	12.845	EPSD	TCGA;ICGC;COSMIC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P16144	ITGB4	P27361	MAPK3	S202	F201V	201	Missense	proximal	-1	no	12.834	12.954	EPSD	TCGA;ICGC;COSMIC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P16144	ITGB4	P27361	MAPK3	S202	S202F	202	Missense	central	0	yes	12.834	0.000	EPSD	TCGA;ICGC;COSMIC	9.358	Loss
CMGC_MAPK_ERK1_MAPK3_ST	P16144	ITGB4	P27361	MAPK3	S377	G380S	380	Missense	distal	3	no	17.332	17.347	EPSD	TCGA;ICGC;COSMIC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P16144	ITGB4	P27361	MAPK3	S377	R382Q	382	Missense	distal	5	no	17.332	17.330	EPSD	TCGA;ICGC;COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P16144	ITGB4	P27361	MAPK3	S377	D376G	376	Missense	proximal	-1	no	17.332	17.313	EPSD	TCGA;ICGC;COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P16144	ITGB4	P27361	MAPK3	S377	R382W	382	Missense	distal	5	no	17.332	16.864	EPSD	TCGA;ICGC;COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P16144	ITGB4	P27361	MAPK3	S377	R373W	373	Missense	distal	-4	no	17.332	17.125	EPSD	TCGA;ICGC;COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P16144	ITGB4	P27361	MAPK3	S397	S397F	397	Missense	central	0	yes	9.948	0.000	EPSD	TCGA;ICGC;COSMIC	9.358	Loss
CMGC_MAPK_ERK1_MAPK3_ST	P16144	ITGB4	P27361	MAPK3	T776	H773R	773	Missense	distal	-3	no	16.164	16.158	EPSD	TCGA;ICGC;COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P16144	ITGB4	P27361	MAPK3	T776	D775N	775	Missense	proximal	-1	no	16.164	16.162	EPSD	TCGA;ICGC;COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P16144	ITGB4	P27361	MAPK3	S1119	M1116K	1116	Missense	distal	-3	no	9.619	9.695	EPSD	TCGA;ICGC;COSMIC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P16144	ITGB4	P27361	MAPK3	S1345	G1340E	1340	Missense	distal	-5	no	10.061	10.070	EPSD	TCGA;ICGC;COSMIC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P16144	ITGB4	P27361	MAPK3	S1345	D1351N	1351	Missense	distal	6	no	10.061	10.008	EPSD	TCGA;ICGC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P16144	ITGB4	P27361	MAPK3	S1345	M1348I	1348	Missense	distal	3	no	10.061	10.071	EPSD	TCGA;ICGC;COSMIC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P16144	ITGB4	P27361	MAPK3	S1345	E1341G	1341	Missense	distal	-4	no	10.061	10.046	EPSD	TCGA;ICGC;COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P16144	ITGB4	P27361	MAPK3	S1356	D1351N	1351	Missense	distal	-5	no	16.245	16.239	PhosphoSitePlus	TCGA;ICGC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P16144	ITGB4	P27361	MAPK3	S1356	R1355C	1355	Missense	proximal	-1	no	16.245	16.060	PhosphoSitePlus	TCGA;ICGC;COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P16144	ITGB4	P27361	MAPK3	S1356	G1359S	1359	Missense	distal	3	no	16.245	16.260	PhosphoSitePlus	TCGA;ICGC;COSMIC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P16144	ITGB4	P27361	MAPK3	S1356	S1358L	1358	Missense	proximal	2	no	16.245	16.222	PhosphoSitePlus	TCGA;ICGC;COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P16144	ITGB4	P27361	MAPK3	S1356	R1362K	1362	Missense	distal	6	no	16.245	16.279	PhosphoSitePlus	TCGA;ICGC;COSMIC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P16144	ITGB4	P27361	MAPK3	S1360	R1355C	1355	Missense	distal	-5	no	10.739	10.623	EPSD	TCGA;ICGC;COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P16144	ITGB4	P27361	MAPK3	S1360	G1359S	1359	Missense	proximal	-1	no	10.739	10.805	EPSD	TCGA;ICGC;COSMIC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P16144	ITGB4	P27361	MAPK3	S1360	S1358L	1358	Missense	proximal	-2	no	10.739	10.431	EPSD	TCGA;ICGC;COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P16144	ITGB4	P27361	MAPK3	S1360	R1362K	1362	Missense	proximal	2	no	10.739	10.735	EPSD	TCGA;ICGC;COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P16144	ITGB4	P27361	MAPK3	S1474	Y1469H	1469	Missense	distal	-5	no	16.072	16.099	EPSD	TCGA;COSMIC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P16144	ITGB4	P27361	MAPK3	S1474	Y1469F	1469	Missense	distal	-5	no	16.072	16.001	EPSD	TCGA;COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P16144	ITGB4	P27361	MAPK3	T1530	R1533C	1533	Missense	distal	3	no	15.543	15.480	EPSD	TCGA;COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P16144	ITGB4	P27361	MAPK3	S1696	V1703M	1703	Missense	distal	7	no	14.845	14.977	EPSD	TCGA;COSMIC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P16144	ITGB4	P27361	MAPK3	S1696	E1698D	1698	Missense	proximal	2	no	14.845	14.842	EPSD	TCGA;COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P16144	ITGB4	P27361	MAPK3	S1696	D1693N	1693	Missense	distal	-3	no	14.845	14.824	EPSD	TCGA;COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P16144	ITGB4	P27361	MAPK3	T1804	T1810A	1810	Missense	distal	6	no	10.793	10.422	EPSD	TCGA;COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P16144	ITGB4	P27361	MAPK3	T1804	T1804A	1804	Missense	central	0	yes	10.793	0.000	EPSD	TCGA	9.358	Loss
CMGC_MAPK_ERK1_MAPK3_ST	P16144	ITGB4	P27361	MAPK3	T1807	T1813S	1813	Missense	distal	6	no	9.270	9.425	EPSD	TCGA;COSMIC	9.358	Gain
CMGC_MAPK_ERK1_MAPK3_ST	P16144	ITGB4	P27361	MAPK3	S1808	T1813S	1813	Missense	distal	5	no	9.657	9.792	EPSD	TCGA;COSMIC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P16144	ITGB4	P27361	MAPK3	S1808	M1815V	1815	Missense	distal	7	no	9.657	9.524	EPSD	TCGA;COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P16144	ITGB4	P27361	MAPK3	S1808	T1810A	1810	Missense	proximal	2	no	9.657	9.629	EPSD	TCGA;COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P16144	ITGB4	P27361	MAPK3	S1808	T1804A	1804	Missense	distal	-4	no	9.657	9.583	EPSD	TCGA	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	O95817	BAG3	P27361	MAPK3	S7	A3T	3	Missense	distal	-4	no	16.326	16.399	EPSD	TCGA;ICGC;COSMIC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	O95817	BAG3	P27361	MAPK3	S7	A4V	4	Missense	distal	-3	no	16.326	16.345	EPSD	TCGA;ICGC;COSMIC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	O95817	BAG3	P27361	MAPK3	S7	V12A	12	Missense	distal	5	no	16.326	16.337	EPSD	TCGA;ICGC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	O95817	BAG3	P27361	MAPK3	S136	S136L	136	Missense	central	0	yes	15.572	0.000	EPSD	TCGA;ICGC;COSMIC	9.358	Loss
CMGC_MAPK_ERK1_MAPK3_ST	O95817	BAG3	P27361	MAPK3	S136	A129V	129	Missense	distal	-7	no	15.572	15.571	EPSD	TCGA;ICGC;COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	O95817	BAG3	P27361	MAPK3	S173	R170W	170	Missense	distal	-3	no	15.221	15.053	EPSD	TCGA;ICGC;COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	O95817	BAG3	P27361	MAPK3	S264	R261Q	261	Missense	distal	-3	no	13.797	13.789	EPSD	TCGA;ICGC;COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	O95817	BAG3	P27361	MAPK3	S279	R276L	276	Missense	distal	-3	no	16.045	16.007	EPSD	TCGA;ICGC;COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	O95817	BAG3	P27361	MAPK3	T285	P292L	292	Missense	distal	7	no	16.402	16.594	PhosphoSitePlus;EPSD	TCGA;ICGC;COSMIC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	O95817	BAG3	P27361	MAPK3	S289	R294H	294	Missense	distal	5	no	16.568	16.604	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	O95817	BAG3	P27361	MAPK3	S289	P292L	292	Missense	distal	3	no	16.568	16.532	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	O95817	BAG3	P27361	MAPK3	S291	R294H	294	Missense	distal	3	no	17.901	17.908	EPSD	TCGA;ICGC;COSMIC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	O95817	BAG3	P27361	MAPK3	S291	P292L	292	Missense	proximal	1	no	17.901	8.863	EPSD	TCGA;ICGC;COSMIC	9.358	Loss
CMGC_MAPK_ERK1_MAPK3_ST	O95817	BAG3	P27361	MAPK3	S386	S386F	386	Missense	central	0	yes	17.196	0.000	EPSD	TCGA;ICGC;COSMIC	9.358	Loss
CMGC_MAPK_ERK1_MAPK3_ST	O95817	BAG3	P27361	MAPK3	T406	A401T	401	Missense	distal	-5	no	13.749	13.832	EPSD	TCGA;ICGC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	O95817	BAG3	P27361	MAPK3	T566	P562S	562	Missense	distal	-4	no	10.269	10.296	EPSD	TCGA;ICGC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	O95817	BAG3	P27361	MAPK3	T568	P562S	562	Missense	distal	-6	no	18.226	18.311	EPSD	TCGA;ICGC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P20339	RAB5A	P27361	MAPK3	S123	S123N	123	Missense	central	0	yes	14.916	0.000	PhosphoSitePlus	TCGA;ICGC;COSMIC	9.358	Loss
CMGC_MAPK_ERK1_MAPK3_ST	P20339	RAB5A	P27361	MAPK3	S193	A191S	191	Missense	proximal	-2	no	8.548	9.823	EPSD	TCGA;ICGC;COSMIC	9.358	Gain
CMGC_MAPK_ERK1_MAPK3_ST	P20339	RAB5A	P27361	MAPK3	T202	V199I	199	Missense	distal	-3	no	11.081	11.042	EPSD	TCGA;ICGC;COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P20339	RAB5A	P27361	MAPK3	T205	V199I	199	Missense	distal	-6	no	11.801	11.732	EPSD	TCGA;ICGC;COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q15648	MED1	P27361	MAPK3	T212	H218Y	218	Missense	distal	6	no	15.272	15.112	EPSD	TCGA;ICGC;COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q15648	MED1	P27361	MAPK3	T212	G209V	209	Missense	distal	-3	no	15.272	15.232	EPSD	TCGA;ICGC;COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q15648	MED1	P27361	MAPK3	S238	E244K	244	Missense	distal	6	no	16.950	16.874	EPSD	TCGA;ICGC;COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q15648	MED1	P27361	MAPK3	S238	K235R	235	Missense	distal	-3	no	16.950	16.963	EPSD	TCGA;ICGC;COSMIC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q15648	MED1	P27361	MAPK3	S434	E441K	441	Missense	distal	7	no	15.651	15.722	EPSD	TCGA;ICGC;COSMIC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q15648	MED1	P27361	MAPK3	S434	S434F	434	Missense	central	0	yes	15.651	0.000	EPSD	TCGA;ICGC;COSMIC	9.358	Loss
CMGC_MAPK_ERK1_MAPK3_ST	Q15648	MED1	P27361	MAPK3	S434	R427I	427	Missense	distal	-7	no	15.651	15.759	EPSD	TCGA;ICGC;COSMIC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q15648	MED1	P27361	MAPK3	S434	P435L	435	Missense	proximal	1	no	15.651	6.613	EPSD	TCGA;ICGC;COSMIC	9.358	Loss
CMGC_MAPK_ERK1_MAPK3_ST	Q15648	MED1	P27361	MAPK3	S434	G436W	436	Missense	proximal	2	no	15.651	15.595	EPSD	TCGA;ICGC;COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q15648	MED1	P27361	MAPK3	T522	P523Q	523	Missense	proximal	1	no	13.472	5.528	EPSD	TCGA;ICGC;COSMIC	9.358	Loss
CMGC_MAPK_ERK1_MAPK3_ST	Q15648	MED1	P27361	MAPK3	T562	P563S	563	Missense	proximal	1	no	15.389	6.336	EPSD	TCGA;ICGC;COSMIC	9.358	Loss
CMGC_MAPK_ERK1_MAPK3_ST	Q15648	MED1	P27361	MAPK3	T562	N565I	565	Missense	distal	3	no	15.389	15.359	EPSD	TCGA;ICGC;COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q15648	MED1	P27361	MAPK3	T562	N555S	555	Missense	distal	-7	no	15.389	15.322	EPSD	TCGA;ICGC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q15648	MED1	P27361	MAPK3	T562	T561N	561	Missense	proximal	-1	no	15.389	15.371	EPSD	TCGA;ICGC;COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q15648	MED1	P27361	MAPK3	T562	M557T	557	Missense	distal	-5	no	15.389	15.492	EPSD	TCGA;ICGC;COSMIC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q15648	MED1	P27361	MAPK3	S621	T628M	628	Missense	distal	7	no	15.019	15.351	EPSD	TCGA;ICGC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q15648	MED1	P27361	MAPK3	S621	P625A	625	Missense	distal	4	no	15.019	14.737	EPSD	TCGA;ICGC;COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q15648	MED1	P27361	MAPK3	S621	H627D	627	Missense	distal	6	no	15.019	15.065	EPSD	TCGA;ICGC;COSMIC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q15648	MED1	P27361	MAPK3	T623	T628M	628	Missense	distal	5	no	15.231	14.976	EPSD	TCGA;ICGC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q15648	MED1	P27361	MAPK3	T623	P625A	625	Missense	proximal	2	no	15.231	15.194	EPSD	TCGA;ICGC;COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q15648	MED1	P27361	MAPK3	T623	H627D	627	Missense	distal	4	no	15.231	15.252	EPSD	TCGA;ICGC;COSMIC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q15648	MED1	P27361	MAPK3	T628	T628M	628	Missense	central	0	yes	15.844	0.000	EPSD	TCGA;ICGC	9.358	Loss
CMGC_MAPK_ERK1_MAPK3_ST	Q15648	MED1	P27361	MAPK3	T628	P625A	625	Missense	distal	-3	no	15.844	15.744	EPSD	TCGA;ICGC;COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q15648	MED1	P27361	MAPK3	T628	S634L	634	Missense	distal	6	no	15.844	15.488	EPSD	TCGA;ICGC;COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q15648	MED1	P27361	MAPK3	T628	H627D	627	Missense	proximal	-1	no	15.844	15.837	EPSD	TCGA;ICGC;COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q15648	MED1	P27361	MAPK3	S664	S671Y	671	Missense	distal	7	no	14.853	15.108	EPSD	TCGA;ICGC;COSMIC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q15648	MED1	P27361	MAPK3	S664	S671F	671	Missense	distal	7	no	14.853	15.344	EPSD	TCGA;ICGC;COSMIC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q15648	MED1	P27361	MAPK3	S675	S682L	682	Missense	distal	7	no	16.204	16.474	EPSD	TCGA;ICGC;COSMIC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q15648	MED1	P27361	MAPK3	S675	S671Y	671	Missense	distal	-4	no	16.204	16.101	EPSD	TCGA;ICGC;COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q15648	MED1	P27361	MAPK3	S675	R677H	677	Missense	proximal	2	no	16.204	16.201	EPSD	TCGA;ICGC;COSMIC;GDSC;CCLE	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q15648	MED1	P27361	MAPK3	S675	R677C	677	Missense	proximal	2	no	16.204	16.155	EPSD	TCGA	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q15648	MED1	P27361	MAPK3	S675	S682T	682	Missense	distal	7	no	16.204	16.322	EPSD	TCGA;ICGC;COSMIC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q15648	MED1	P27361	MAPK3	S675	S671F	671	Missense	distal	-4	no	16.204	16.015	EPSD	TCGA;ICGC;COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q15648	MED1	P27361	MAPK3	T805	S810Y	810	Missense	distal	5	no	15.425	15.209	EPSD	TCGA;ICGC;COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q15648	MED1	P27361	MAPK3	S848	G847R	847	Missense	proximal	-1	no	15.619	15.643	EPSD	TCGA;ICGC;COSMIC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q15648	MED1	P27361	MAPK3	S853	G847R	847	Missense	distal	-6	no	17.767	17.669	EPSD	TCGA;ICGC;COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q15648	MED1	P27361	MAPK3	S887	D891G	891	Missense	distal	4	no	9.678	9.637	EPSD	TCGA;ICGC;COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q15648	MED1	P27361	MAPK3	S887	S889T	889	Missense	proximal	2	no	9.678	9.667	EPSD	TCGA;ICGC;COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q15648	MED1	P27361	MAPK3	S1021	H1024Y	1024	Missense	distal	3	no	15.783	15.767	EPSD	TCGA;ICGC;COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q15648	MED1	P27361	MAPK3	S1023	H1024Y	1024	Missense	proximal	1	no	9.492	10.199	EPSD	TCGA;ICGC;COSMIC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q15648	MED1	P27361	MAPK3	S1042	S1049C	1049	Missense	distal	7	no	17.902	18.514	EPSD	TCGA;ICGC;COSMIC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q15648	MED1	P27361	MAPK3	S1045	S1049C	1049	Missense	distal	4	no	9.698	9.195	EPSD	TCGA;ICGC;COSMIC	9.358	Loss
CMGC_MAPK_ERK1_MAPK3_ST	Q15648	MED1	P27361	MAPK3	T1051	S1049C	1049	Missense	proximal	-2	no	14.190	11.750	EPSD	TCGA;ICGC;COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q15648	MED1	P27361	MAPK3	S1090	S1091F	1091	Missense	proximal	1	no	8.225	11.065	EPSD	TCGA;ICGC;COSMIC	9.358	Gain
CMGC_MAPK_ERK1_MAPK3_ST	Q15648	MED1	P27361	MAPK3	S1155	S1156F	1156	Missense	proximal	1	no	7.655	10.495	EPSD	TCGA;ICGC;COSMIC	9.358	Gain
CMGC_MAPK_ERK1_MAPK3_ST	Q15648	MED1	P27361	MAPK3	S1156	G1154D	1154	Missense	proximal	-2	no	16.897	17.407	EPSD	TCGA;ICGC;COSMIC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q15648	MED1	P27361	MAPK3	S1156	S1149F	1149	Missense	distal	-7	no	16.897	17.116	EPSD	TCGA;ICGC;COSMIC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q15648	MED1	P27361	MAPK3	S1156	S1156F	1156	Missense	central	0	yes	16.897	0.000	EPSD	TCGA;ICGC;COSMIC	9.358	Loss
CMGC_MAPK_ERK1_MAPK3_ST	Q15648	MED1	P27361	MAPK3	S1192	H1195Y	1195	Missense	distal	3	no	14.651	14.635	EPSD	TCGA;ICGC;COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q15648	MED1	P27361	MAPK3	S1207	P1208A	1208	Missense	proximal	1	no	14.894	5.655	EPSD	TCGA;ICGC;COSMIC	9.358	Loss
CMGC_MAPK_ERK1_MAPK3_ST	Q15648	MED1	P27361	MAPK3	T1215	P1208A	1208	Missense	distal	-7	no	16.152	16.264	EPSD	TCGA;ICGC;COSMIC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q15648	MED1	P27361	MAPK3	T1215	S1218C	1218	Missense	distal	3	no	16.152	16.066	EPSD	TCGA;ICGC;COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q15648	MED1	P27361	MAPK3	S1223	S1227L	1227	Missense	distal	4	no	15.688	15.485	EPSD	TCGA;ICGC;COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q15648	MED1	P27361	MAPK3	S1223	S1218C	1218	Missense	distal	-5	no	15.688	15.526	EPSD	TCGA;ICGC;COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q15648	MED1	P27361	MAPK3	S1294	P1301L	1301	Missense	distal	7	no	15.910	16.103	EPSD	TCGA;ICGC;COSMIC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q15648	MED1	P27361	MAPK3	S1401	P1402R	1402	Missense	proximal	1	no	16.180	6.679	EPSD	TCGA;ICGC;COSMIC	9.358	Loss
CMGC_MAPK_ERK1_MAPK3_ST	Q15648	MED1	P27361	MAPK3	S1401	V1408M	1408	Missense	distal	7	no	16.180	16.312	EPSD	TCGA;ICGC;COSMIC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q15648	MED1	P27361	MAPK3	S1401	K1407T	1407	Missense	distal	6	no	16.180	16.233	EPSD	TCGA;ICGC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q15648	MED1	P27361	MAPK3	S1433	S1439F	1439	Missense	distal	6	no	17.484	16.771	EPSD	TCGA;ICGC;COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q15648	MED1	P27361	MAPK3	S1433	P1434L	1434	Missense	proximal	1	no	17.484	8.446	EPSD	TCGA;ICGC;COSMIC	9.358	Loss
CMGC_MAPK_ERK1_MAPK3_ST	Q15648	MED1	P27361	MAPK3	S1433	I1436M	1436	Missense	distal	3	no	17.484	17.474	EPSD	TCGA;ICGC;COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q15648	MED1	P27361	MAPK3	T1440	S1439F	1439	Missense	proximal	-1	no	13.736	13.532	EPSD	TCGA;ICGC;COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q15648	MED1	P27361	MAPK3	T1440	P1434L	1434	Missense	distal	-6	no	13.736	13.489	EPSD	TCGA;ICGC;COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q15648	MED1	P27361	MAPK3	T1440	I1436M	1436	Missense	distal	-4	no	13.736	13.716	EPSD	TCGA;ICGC;COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q15648	MED1	P27361	MAPK3	S1447	P1448S	1448	Missense	proximal	1	no	16.294	7.241	EPSD	TCGA;ICGC;COSMIC	9.358	Loss
CMGC_MAPK_ERK1_MAPK3_ST	Q15648	MED1	P27361	MAPK3	S1447	P1448A	1448	Missense	proximal	1	no	16.294	7.055	EPSD	TCGA;ICGC;COSMIC	9.358	Loss
CMGC_MAPK_ERK1_MAPK3_ST	Q15648	MED1	P27361	MAPK3	S1449	P1448S	1448	Missense	proximal	-1	no	9.714	9.708	EPSD	TCGA;ICGC;COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q15648	MED1	P27361	MAPK3	S1449	P1448A	1448	Missense	proximal	-1	no	9.714	9.575	EPSD	TCGA;ICGC;COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q15648	MED1	P27361	MAPK3	S1453	P1448S	1448	Missense	distal	-5	no	17.235	17.240	EPSD	TCGA;ICGC;COSMIC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q15648	MED1	P27361	MAPK3	S1453	P1448A	1448	Missense	distal	-5	no	17.235	17.141	EPSD	TCGA;ICGC;COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q15648	MED1	P27361	MAPK3	S1479	Q1477H	1477	Missense	proximal	-2	no	16.450	16.986	EPSD	TCGA;ICGC;COSMIC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q15648	MED1	P27361	MAPK3	S1479	S1475F	1475	Missense	distal	-4	no	16.450	16.261	EPSD	TCGA	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q15648	MED1	P27361	MAPK3	S1479	D1484V	1484	Missense	distal	5	no	16.450	16.226	EPSD	TCGA;ICGC;COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q15648	MED1	P27361	MAPK3	S1479	D1484N	1484	Missense	distal	5	no	16.450	16.370	EPSD	TCGA;ICGC;COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q15648	MED1	P27361	MAPK3	S1532	H1526D	1526	Missense	distal	-6	no	9.482	9.586	EPSD	TCGA;ICGC;COSMIC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q15648	MED1	P27361	MAPK3	S1532	S1527G	1527	Missense	distal	-5	no	9.482	9.439	EPSD	TCGA;ICGC;COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q15648	MED1	P27361	MAPK3	S1558	S1558L	1558	Missense	central	0	yes	10.298	0.000	EPSD	TCGA;ICGC;COSMIC	9.358	Loss
CMGC_MAPK_ERK1_MAPK3_ST	Q15648	MED1	P27361	MAPK3	S1558	A1554S	1554	Missense	distal	-4	no	10.298	10.430	EPSD	TCGA;ICGC;COSMIC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q15648	MED1	P27361	MAPK3	S1558	S1561I	1561	Missense	distal	3	no	10.298	10.247	EPSD	TCGA;ICGC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q15648	MED1	P27361	MAPK3	S1561	S1558L	1558	Missense	distal	-3	no	17.939	17.863	EPSD	TCGA;ICGC;COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q15648	MED1	P27361	MAPK3	S1561	A1554S	1554	Missense	distal	-7	no	17.939	17.789	EPSD	TCGA;ICGC;COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q15648	MED1	P27361	MAPK3	S1561	S1561I	1561	Missense	central	0	yes	17.939	0.000	EPSD	TCGA;ICGC	9.358	Loss
CMGC_MAPK_ERK1_MAPK3_ST	O75582	RPS6KA5	P27361	MAPK3	S253	S253Y	253	Missense	central	0	yes	14.937	0.000	EPSD	TCGA;ICGC;COSMIC	9.358	Loss
CMGC_MAPK_ERK1_MAPK3_ST	O75582	RPS6KA5	P27361	MAPK3	S253	D258N	258	Missense	distal	5	no	14.937	14.857	EPSD	TCGA;ICGC;COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	O75582	RPS6KA5	P27361	MAPK3	S360	T353A	353	Missense	distal	-7	no	17.950	18.023	PhosphoSitePlus;EPSD	TCGA;COSMIC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	O75582	RPS6KA5	P27361	MAPK3	S376	Y375F	375	Missense	proximal	-1	no	9.775	9.648	EPSD	TCGA;ICGC;COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	O75582	RPS6KA5	P27361	MAPK3	S376	S376C	376	Missense	central	0	yes	9.775	0.000	EPSD	TCGA;ICGC	9.358	Loss
CMGC_MAPK_ERK1_MAPK3_ST	O75582	RPS6KA5	P27361	MAPK3	S376	L383I	383	Missense	distal	7	no	9.775	9.904	EPSD	TCGA;ICGC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	O75582	RPS6KA5	P27361	MAPK3	T581	K580N	580	Missense	proximal	-1	no	17.145	17.151	EPSD;PhosphoSitePlus	TCGA;COSMIC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	O75582	RPS6KA5	P27361	MAPK3	T581	H587Q	587	Missense	distal	6	no	17.145	17.057	EPSD;PhosphoSitePlus	TCGA;ICGC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	O75582	RPS6KA5	P27361	MAPK3	T700	P701L	701	Missense	proximal	1	no	16.688	7.650	EPSD	TCGA;COSMIC	9.358	Loss
CMGC_MAPK_ERK1_MAPK3_ST	O75582	RPS6KA5	P27361	MAPK3	T700	I703S	703	Missense	distal	3	no	16.688	16.739	EPSD	TCGA;ICGC;COSMIC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	O75582	RPS6KA5	P27361	MAPK3	S767	S768F	768	Missense	proximal	1	no	9.155	11.995	EPSD	TCGA	9.358	Gain
CMGC_MAPK_ERK1_MAPK3_ST	O75582	RPS6KA5	P27361	MAPK3	S768	H769Y	769	Missense	proximal	1	no	9.457	10.164	EPSD	TCGA;COSMIC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	O75582	RPS6KA5	P27361	MAPK3	S768	T775S	775	Missense	distal	7	no	9.457	9.338	EPSD	TCGA;COSMIC;GDSC;CCLE	9.358	Loss
CMGC_MAPK_ERK1_MAPK3_ST	O75582	RPS6KA5	P27361	MAPK3	S768	S768F	768	Missense	central	0	yes	9.457	0.000	EPSD	TCGA	9.358	Loss
CMGC_MAPK_ERK1_MAPK3_ST	O75582	RPS6KA5	P27361	MAPK3	S770	H769Y	769	Missense	proximal	-1	no	10.362	10.324	EPSD	TCGA;COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	O75582	RPS6KA5	P27361	MAPK3	S770	T775S	775	Missense	distal	5	no	10.362	10.497	EPSD	TCGA;COSMIC;GDSC;CCLE	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	O75582	RPS6KA5	P27361	MAPK3	S770	S768F	768	Missense	proximal	-2	no	10.362	9.062	EPSD	TCGA	9.358	Loss
CMGC_MAPK_ERK1_MAPK3_ST	O75582	RPS6KA5	P27361	MAPK3	T775	H769Y	769	Missense	distal	-6	no	17.486	17.397	EPSD	TCGA;COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	O75582	RPS6KA5	P27361	MAPK3	T775	P782H	782	Missense	distal	7	no	17.486	17.546	EPSD	TCGA	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	O75582	RPS6KA5	P27361	MAPK3	T775	S768F	768	Missense	distal	-7	no	17.486	17.705	EPSD	TCGA	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	O75582	RPS6KA5	P27361	MAPK3	S788	N789D	789	Missense	proximal	1	no	3.931	9.418	EPSD	TCGA;COSMIC	9.358	Gain
CMGC_MAPK_ERK1_MAPK3_ST	O75582	RPS6KA5	P27361	MAPK3	T793	F797L	797	Missense	distal	4	no	9.895	10.106	EPSD	TCGA;COSMIC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	O75582	RPS6KA5	P27361	MAPK3	T793	N789D	789	Missense	distal	-4	no	9.895	9.921	EPSD	TCGA;COSMIC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	O75582	RPS6KA5	P27361	MAPK3	T793	D787V	787	Missense	distal	-6	no	9.895	9.626	EPSD	TCGA;COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P29590	PML	P27361	MAPK3	S40	A47T	47	Missense	distal	7	no	16.781	16.554	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P29590	PML	P27361	MAPK3	T196	R195C	195	Missense	proximal	-1	no	16.585	16.400	EPSD	TCGA;ICGC;COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P29590	PML	P27361	MAPK3	T196	S190C	190	Missense	distal	-6	no	16.585	16.026	EPSD	TCGA;ICGC;COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P29590	PML	P27361	MAPK3	T196	R195H	195	Missense	proximal	-1	no	16.585	16.588	EPSD	TCGA;ICGC;COSMIC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P29590	PML	P27361	MAPK3	S403	P410S	410	Missense	distal	7	no	15.600	15.522	EPSD	TCGA;ICGC;COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P29590	PML	P27361	MAPK3	S403	E405K	405	Missense	proximal	2	no	15.600	15.592	EPSD	TCGA;ICGC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P29590	PML	P27361	MAPK3	T409	P410S	410	Missense	proximal	1	no	14.911	5.857	EPSD	TCGA;ICGC;COSMIC	9.358	Loss
CMGC_MAPK_ERK1_MAPK3_ST	P29590	PML	P27361	MAPK3	T409	E405K	405	Missense	distal	-4	no	14.911	14.851	EPSD	TCGA;ICGC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P29590	PML	P27361	MAPK3	T409	P413L	413	Missense	distal	4	no	14.911	14.756	EPSD	TCGA;ICGC;COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P29590	PML	P27361	MAPK3	S505	L501F	501	Missense	distal	-4	no	14.608	14.559	EPSD	TCGA;ICGC;COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P29590	PML	P27361	MAPK3	S518	S518L	518	Missense	central	0	yes	16.965	0.000	EPSD	TCGA;ICGC;COSMIC	9.358	Loss
CMGC_MAPK_ERK1_MAPK3_ST	P29590	PML	P27361	MAPK3	S583	S582P	582	Missense	proximal	-1	no	9.745	9.750	EPSD	TCGA	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P29590	PML	P27361	MAPK3	T867	R861L	861	Missense	distal	-6	no	17.550	17.379	EPSD	TCGA;ICGC;COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P29590	PML	P27361	MAPK3	S879	E876D	876	Missense	distal	-3	no	11.285	11.281	EPSD	TCGA;ICGC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	O15027	SEC16A	P27361	MAPK3	S1623	E1617D	1617	Missense	distal	-6	no	10.809	10.765	EPSD	TCGA;ICGC;COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	O15027	SEC16A	P27361	MAPK3	T1876	A1873T	1873	Missense	distal	-3	no	13.176	13.237	EPSD	TCGA;ICGC;COSMIC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	O15027	SEC16A	P27361	MAPK3	S1905	P1901S	1901	Missense	distal	-4	no	18.669	18.696	EPSD	TCGA;ICGC;COSMIC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q9NRA0	SPHK2	P27361	MAPK3	S107	S111L	111	Missense	distal	4	no	15.947	15.744	EPSD	TCGA;COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q9NRA0	SPHK2	P27361	MAPK3	S107	R106C	106	Missense	proximal	-1	no	15.947	15.762	EPSD	TCGA;COSMIC;GDSC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q9NRA0	SPHK2	P27361	MAPK3	T404	D406Y	406	Missense	proximal	2	no	15.509	15.499	EPSD	TCGA;COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q9NRA0	SPHK2	P27361	MAPK3	S414	R418H	418	Missense	distal	4	no	15.285	15.291	EPSD	TCGA;COSMIC;CCLE	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q9NRA0	SPHK2	P27361	MAPK3	S473	S472F	472	Missense	proximal	-1	no	16.344	16.139	EPSD	TCGA;COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q9NRA0	SPHK2	P27361	MAPK3	S473	P467S	467	Missense	distal	-6	no	16.344	16.428	EPSD	TCGA;COSMIC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q9NRA0	SPHK2	P27361	MAPK3	S477	S472F	472	Missense	distal	-5	no	17.035	16.900	EPSD	TCGA;COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q9NRA0	SPHK2	P27361	MAPK3	S477	S484P	484	Missense	distal	7	no	17.035	17.112	EPSD	TCGA;COSMIC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q9NRA0	SPHK2	P27361	MAPK3	S484	S484P	484	Missense	central	0	yes	17.628	0.000	EPSD	TCGA;COSMIC	9.358	Loss
CMGC_MAPK_ERK1_MAPK3_ST	Q9NRA0	SPHK2	P27361	MAPK3	T503	S497C	497	Missense	distal	-6	no	14.766	14.207	EPSD	TCGA;COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q9NRA0	SPHK2	P27361	MAPK3	T503	L499F	499	Missense	distal	-4	no	14.766	14.717	EPSD	TCGA;COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q9NRA0	SPHK2	P27361	MAPK3	T503	P502S	502	Missense	proximal	-1	no	14.766	14.760	EPSD	TCGA	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P05412	JUN	P27361	MAPK3	S73	S73L	73	Missense	central	0	yes	16.312	0.000	PhosphoSitePlus;EPSD	TCGA;ICGC;COSMIC	9.358	Loss
CMGC_MAPK_ERK1_MAPK3_ST	P05412	JUN	P27361	MAPK3	T91	G86W	86	Missense	distal	-5	no	15.046	14.890	EPSD	TCGA;ICGC;COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P05412	JUN	P27361	MAPK3	T93	G86W	86	Missense	distal	-7	no	12.688	12.979	EPSD	TCGA;ICGC;COSMIC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P05412	JUN	P27361	MAPK3	T93	C99Y	99	Missense	distal	6	no	12.688	13.173	EPSD	TCGA;ICGC;COSMIC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P05412	JUN	P27361	MAPK3	T239	P244L	244	Missense	distal	5	no	15.173	14.946	EPSD	TCGA;ICGC;COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P05412	JUN	P27361	MAPK3	S243	P244L	244	Missense	proximal	1	no	18.294	9.256	EPSD	TCGA;ICGC;COSMIC	9.358	Loss
CMGC_MAPK_ERK1_MAPK3_ST	P05412	JUN	P27361	MAPK3	T325	M323V	323	Missense	proximal	-2	no	8.383	9.483	EPSD	TCGA;ICGC;COSMIC	9.358	Gain
CMGC_MAPK_ERK1_MAPK3_ST	P05412	JUN	P27361	MAPK3	T330	M323V	323	Missense	distal	-7	no	11.215	11.159	EPSD	TCGA;ICGC;COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q03060	CREM	P27361	MAPK3	S24	E20G	20	Missense	distal	-4	no	11.372	11.358	EPSD	TCGA;ICGC;COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q03060	CREM	P27361	MAPK3	S24	G28V	28	Missense	distal	4	no	11.372	11.309	EPSD	TCGA;ICGC;COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q02750	MAP2K1	P27361	MAPK3	S24	N21T	21	Missense	distal	-3	no	9.481	9.496	EPSD	TCGA	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q02750	MAP2K1	P27361	MAPK3	S24	E31V	31	Missense	distal	7	no	9.481	9.695	EPSD	TCGA;ICGC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q02750	MAP2K1	P27361	MAPK3	S25	N21T	21	Missense	distal	-4	no	11.000	11.003	EPSD	TCGA	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q02750	MAP2K1	P27361	MAPK3	S25	E31V	31	Missense	distal	6	no	11.000	10.694	EPSD	TCGA;ICGC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q02750	MAP2K1	P27361	MAPK3	T55	Q56P	56	Missense	proximal	1	no	6.232	14.176	EPSD	TCGA;ICGC;COSMIC;GDSC;CCLE	9.358	Gain
CMGC_MAPK_ERK1_MAPK3_ST	Q02750	MAP2K1	P27361	MAPK3	S231	L235H	235	Missense	distal	4	no	17.940	18.003	EPSD	TCGA;ICGC;COSMIC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q02750	MAP2K1	P27361	MAPK3	S231	S231L	231	Missense	central	0	yes	17.940	0.000	EPSD	TCGA;ICGC;COSMIC	9.358	Loss
CMGC_MAPK_ERK1_MAPK3_ST	Q02750	MAP2K1	P27361	MAPK3	S231	V224M	224	Missense	distal	-7	no	17.940	17.996	EPSD	TCGA;ICGC;COSMIC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q02750	MAP2K1	P27361	MAPK3	S231	R227K	227	Missense	distal	-4	no	17.940	17.933	EPSD	TCGA;ICGC;COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q02750	MAP2K1	P27361	MAPK3	T286	P290S	290	Missense	distal	4	no	14.936	14.985	PhosphoSitePlus;EPSD	TCGA;ICGC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q02750	MAP2K1	P27361	MAPK3	T292	G294R	294	Missense	proximal	2	no	16.441	16.445	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q02750	MAP2K1	P27361	MAPK3	T292	G294V	294	Missense	proximal	2	no	16.441	16.432	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q02750	MAP2K1	P27361	MAPK3	T292	G294E	294	Missense	proximal	2	no	16.441	16.449	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q02750	MAP2K1	P27361	MAPK3	T292	P290S	290	Missense	proximal	-2	no	16.441	15.365	EPSD;PhosphoSitePlus	TCGA;ICGC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q02750	MAP2K1	P27361	MAPK3	S299	G294R	294	Missense	distal	-5	no	9.721	9.719	EPSD	TCGA;ICGC;COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q02750	MAP2K1	P27361	MAPK3	S299	G294V	294	Missense	distal	-5	no	9.721	9.689	EPSD	TCGA;ICGC;COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q02750	MAP2K1	P27361	MAPK3	S299	G294E	294	Missense	distal	-5	no	9.721	9.730	EPSD	TCGA;ICGC;COSMIC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q02750	MAP2K1	P27361	MAPK3	S299	R305Q	305	Missense	distal	6	no	9.721	9.652	EPSD	TCGA;ICGC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q02750	MAP2K1	P27361	MAPK3	S299	D303N	303	Missense	distal	4	no	9.721	9.694	EPSD	TCGA;ICGC;COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q00613	HSF1	P27361	MAPK3	S244	S250C	250	Missense	distal	6	no	15.761	14.894	EPSD	TCGA;COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q00613	HSF1	P27361	MAPK3	S275	P276L	276	Missense	proximal	1	no	17.431	8.393	EPSD	TCGA;COSMIC	9.358	Loss
CMGC_MAPK_ERK1_MAPK3_ST	Q00613	HSF1	P27361	MAPK3	S275	M277V	277	Missense	proximal	2	no	17.431	17.449	EPSD	TCGA;COSMIC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q00613	HSF1	P27361	MAPK3	S279	P276L	276	Missense	distal	-3	no	14.389	14.305	EPSD	TCGA;COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q00613	HSF1	P27361	MAPK3	S279	E286K	286	Missense	distal	7	no	14.389	14.460	EPSD	TCGA;COSMIC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q00613	HSF1	P27361	MAPK3	S279	M277V	277	Missense	proximal	-2	no	14.389	15.489	EPSD	TCGA;COSMIC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q00613	HSF1	P27361	MAPK3	S292	R296C	296	Missense	distal	4	no	16.604	16.247	EPSD	TCGA;COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q00613	HSF1	P27361	MAPK3	S292	P288L	288	Missense	distal	-4	no	16.604	16.492	EPSD	TCGA;COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q00613	HSF1	P27361	MAPK3	S292	E286K	286	Missense	distal	-6	no	16.604	16.463	EPSD	TCGA;COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q00613	HSF1	P27361	MAPK3	S303	E300Q	300	Missense	distal	-3	no	17.854	17.828	EPSD	TCGA	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q00613	HSF1	P27361	MAPK3	S303	R296C	296	Missense	distal	-7	no	17.854	18.041	EPSD	TCGA;COSMIC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q00613	HSF1	P27361	MAPK3	S307	E300Q	300	Missense	distal	-7	no	16.210	16.260	PhosphoSitePlus;EPSD	TCGA	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q00613	HSF1	P27361	MAPK3	S314	R317H	317	Missense	distal	3	no	17.255	17.263	EPSD	TCGA;COSMIC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q00613	HSF1	P27361	MAPK3	S314	S320F	320	Missense	distal	6	no	17.255	16.541	EPSD	TCGA;COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q00613	HSF1	P27361	MAPK3	S326	D332Y	332	Missense	distal	6	no	15.827	15.621	EPSD;PhosphoSitePlus	TCGA;COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q00613	HSF1	P27361	MAPK3	S326	T323I	323	Missense	distal	-3	no	15.827	15.745	EPSD;PhosphoSitePlus	TCGA;COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q00613	HSF1	P27361	MAPK3	S326	S320F	320	Missense	distal	-6	no	15.827	15.359	EPSD;PhosphoSitePlus	TCGA;COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q00613	HSF1	P27361	MAPK3	S326	A329T	329	Missense	distal	3	no	15.827	15.857	EPSD;PhosphoSitePlus	TCGA;COSMIC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q00613	HSF1	P27361	MAPK3	S326	S333F	333	Missense	distal	7	no	15.827	16.317	EPSD;PhosphoSitePlus	TCGA;COSMIC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q00613	HSF1	P27361	MAPK3	S326	P327L	327	Missense	proximal	1	no	15.827	6.789	EPSD;PhosphoSitePlus	TCGA	9.358	Loss
CMGC_MAPK_ERK1_MAPK3_ST	Q00613	HSF1	P27361	MAPK3	S363	P364S	364	Missense	proximal	1	no	17.748	8.695	EPSD	TCGA;COSMIC	9.358	Loss
CMGC_MAPK_ERK1_MAPK3_ST	Q00613	HSF1	P27361	MAPK3	T369	P364S	364	Missense	distal	-5	no	15.694	15.699	EPSD	TCGA;COSMIC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q00613	HSF1	P27361	MAPK3	S419	P420L	420	Missense	proximal	1	no	15.478	6.440	EPSD	TCGA;ICGC;COSMIC	9.358	Loss
CMGC_MAPK_ERK1_MAPK3_ST	Q00613	HSF1	P27361	MAPK3	S419	P425S	425	Missense	distal	6	no	15.478	15.607	EPSD	TCGA;ICGC;COSMIC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q00613	HSF1	P27361	MAPK3	S444	E441K	441	Missense	distal	-3	no	18.515	18.484	EPSD	TCGA;COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q00613	HSF1	P27361	MAPK3	S458	E453K	453	Missense	distal	-5	no	15.842	15.830	EPSD	TCGA;COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q00613	HSF1	P27361	MAPK3	S498	E493K	493	Missense	distal	-5	no	9.746	9.734	EPSD	TCGA;ICGC;COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q00613	HSF1	P27361	MAPK3	S498	F500L	500	Missense	proximal	2	no	9.746	9.773	EPSD	TCGA;ICGC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q00613	HSF1	P27361	MAPK3	T511	A507V	507	Missense	distal	-4	no	9.425	9.405	EPSD	TCGA;ICGC;COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q00613	HSF1	P27361	MAPK3	S513	A507V	507	Missense	distal	-6	no	9.594	9.580	EPSD	TCGA;ICGC;COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q9UIG0	BAZ1B	P27361	MAPK3	S158	E164D	164	Missense	distal	6	no	15.160	15.115	PhosphoSitePlus	TCGA;ICGC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q9UIG0	BAZ1B	P27361	MAPK3	S161	S166Y	166	Missense	distal	5	no	10.489	10.273	EPSD	TCGA	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q9UIG0	BAZ1B	P27361	MAPK3	S161	Q168E	168	Missense	distal	7	no	10.489	10.394	EPSD	TCGA;ICGC;COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q9UIG0	BAZ1B	P27361	MAPK3	S161	E164D	164	Missense	distal	3	no	10.489	10.491	EPSD	TCGA;ICGC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q9UIG0	BAZ1B	P27361	MAPK3	S197	S204L	204	Missense	distal	7	no	17.898	18.167	EPSD	TCGA;ICGC;COSMIC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q9UIG0	BAZ1B	P27361	MAPK3	S197	R199Q	199	Missense	proximal	2	no	17.898	17.888	EPSD	TCGA;ICGC;COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q9UIG0	BAZ1B	P27361	MAPK3	S197	P202R	202	Missense	distal	5	no	17.898	17.797	EPSD	TCGA;ICGC;COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q9UIG0	BAZ1B	P27361	MAPK3	S197	R195H	195	Missense	proximal	-2	no	17.898	18.070	EPSD	TCGA;ICGC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q9UIG0	BAZ1B	P27361	MAPK3	S197	D192N	192	Missense	distal	-5	no	17.898	17.892	EPSD	TCGA	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q9UIG0	BAZ1B	P27361	MAPK3	S312	T310S	310	Missense	proximal	-2	no	17.440	17.350	EPSD	TCGA;ICGC;COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q9UIG0	BAZ1B	P27361	MAPK3	S349	L342F	342	Missense	distal	-7	no	14.444	14.519	EPSD	TCGA;ICGC;COSMIC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q9UIG0	BAZ1B	P27361	MAPK3	S349	G348D	348	Missense	proximal	-1	no	14.444	14.463	EPSD	TCGA;ICGC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q9UIG0	BAZ1B	P27361	MAPK3	S361	P362H	362	Missense	proximal	1	no	16.637	8.881	EPSD	TCGA;ICGC;COSMIC	9.358	Loss
CMGC_MAPK_ERK1_MAPK3_ST	Q9UIG0	BAZ1B	P27361	MAPK3	S361	E364Q	364	Missense	distal	3	no	16.637	16.628	EPSD	TCGA;ICGC;COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q9UIG0	BAZ1B	P27361	MAPK3	S361	P362S	362	Missense	proximal	1	no	16.637	7.583	EPSD	TCGA;ICGC;COSMIC	9.358	Loss
CMGC_MAPK_ERK1_MAPK3_ST	Q9UIG0	BAZ1B	P27361	MAPK3	S374	H379Q	379	Missense	distal	5	no	13.797	13.759	EPSD	TCGA;ICGC;COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q9UIG0	BAZ1B	P27361	MAPK3	S374	M372I	372	Missense	proximal	-2	no	13.797	14.713	EPSD	TCGA;ICGC;COSMIC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q9UIG0	BAZ1B	P27361	MAPK3	S374	N376D	376	Missense	proximal	2	no	13.797	13.803	EPSD	TCGA;ICGC;COSMIC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q9UIG0	BAZ1B	P27361	MAPK3	S374	P375S	375	Missense	proximal	1	no	13.797	4.743	EPSD	TCGA;ICGC;COSMIC	9.358	Loss
CMGC_MAPK_ERK1_MAPK3_ST	Q9UIG0	BAZ1B	P27361	MAPK3	S374	S374L	374	Missense	central	0	yes	13.797	0.000	EPSD	TCGA;ICGC;COSMIC	9.358	Loss
CMGC_MAPK_ERK1_MAPK3_ST	Q9UIG0	BAZ1B	P27361	MAPK3	S423	L428P	428	Missense	distal	5	no	16.421	16.648	EPSD	TCGA;ICGC;COSMIC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q9UIG0	BAZ1B	P27361	MAPK3	S423	S417F	417	Missense	distal	-6	no	16.421	15.953	EPSD	TCGA;ICGC;COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q9UIG0	BAZ1B	P27361	MAPK3	T430	L428P	428	Missense	proximal	-2	no	15.578	16.962	EPSD	TCGA;ICGC;COSMIC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q9UIG0	BAZ1B	P27361	MAPK3	T430	P431S	431	Missense	proximal	1	no	15.578	6.524	EPSD	TCGA;ICGC;COSMIC	9.358	Loss
CMGC_MAPK_ERK1_MAPK3_ST	Q9UIG0	BAZ1B	P27361	MAPK3	T460	R455Q	455	Missense	distal	-5	no	14.590	14.582	EPSD	TCGA;ICGC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q9UIG0	BAZ1B	P27361	MAPK3	T460	T460A	460	Missense	central	0	yes	14.590	0.000	EPSD	TCGA;ICGC;COSMIC;GDSC;CCLE	9.358	Loss
CMGC_MAPK_ERK1_MAPK3_ST	Q9UIG0	BAZ1B	P27361	MAPK3	T460	G459D	459	Missense	proximal	-1	no	14.590	14.609	EPSD	TCGA;ICGC;COSMIC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q9UIG0	BAZ1B	P27361	MAPK3	T983	V977I	977	Missense	distal	-6	no	15.432	15.364	EPSD	TCGA;ICGC;COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q9UIG0	BAZ1B	P27361	MAPK3	S1468	A1472V	1472	Missense	distal	4	no	9.795	9.903	EPSD	TCGA;ICGC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q9UIG0	BAZ1B	P27361	MAPK3	S1468	G1466W	1466	Missense	proximal	-2	no	9.795	8.615	EPSD	TCGA;ICGC;COSMIC	9.358	Loss
CMGC_MAPK_ERK1_MAPK3_ST	Q9UIG0	BAZ1B	P27361	MAPK3	S1476	A1472V	1472	Missense	distal	-4	no	9.496	9.476	EPSD	TCGA;ICGC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q9ULV5	HSF4	P27361	MAPK3	S52	R53H	53	Missense	proximal	1	no	7.773	9.518	EPSD	TCGA	9.358	Gain
CMGC_MAPK_ERK1_MAPK3_ST	Q9ULV5	HSF4	P27361	MAPK3	S298	G300E	300	Missense	proximal	2	no	17.561	17.569	PhosphoSitePlus	TCGA;ICGC;COSMIC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q9ULV5	HSF4	P27361	MAPK3	S298	E304K	304	Missense	distal	6	no	17.561	17.485	PhosphoSitePlus	TCGA;ICGC;COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q9ULV5	HSF4	P27361	MAPK3	S298	A297T	297	Missense	proximal	-1	no	17.561	17.665	PhosphoSitePlus	TCGA;ICGC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q9ULV5	HSF4	P27361	MAPK3	S298	A297V	297	Missense	proximal	-1	no	17.561	17.611	PhosphoSitePlus	TCGA;ICGC;COSMIC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q9ULV5	HSF4	P27361	MAPK3	S298	P296L	296	Missense	proximal	-2	no	17.561	16.177	PhosphoSitePlus	TCGA;ICGC;COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q9ULV5	HSF4	P27361	MAPK3	S298	A305V	305	Missense	distal	7	no	17.561	17.533	PhosphoSitePlus	TCGA;ICGC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q9ULV5	HSF4	P27361	MAPK3	S340	S338R	338	Missense	proximal	-2	no	14.072	13.748	EPSD	TCGA;ICGC;COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q9ULV5	HSF4	P27361	MAPK3	S340	S340I	340	Missense	central	0	yes	14.072	0.000	EPSD	TCGA;ICGC;COSMIC	9.358	Loss
CMGC_MAPK_ERK1_MAPK3_ST	Q9ULV5	HSF4	P27361	MAPK3	S340	E342G	342	Missense	proximal	2	no	14.072	14.064	EPSD	TCGA;ICGC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q9ULV5	HSF4	P27361	MAPK3	S489	S491F	491	Missense	proximal	2	no	18.414	18.364	EPSD	TCGA;ICGC;COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q9ULV5	HSF4	P27361	MAPK3	S489	S491P	491	Missense	proximal	2	no	18.414	18.412	EPSD	TCGA;COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q9ULV5	HSF4	P27361	MAPK3	S489	S489G	489	Missense	central	0	yes	18.414	0.000	EPSD	TCGA;ICGC;COSMIC	9.358	Loss
CMGC_MAPK_ERK1_MAPK3_ST	Q9ULV5	HSF4	P27361	MAPK3	S491	S491F	491	Missense	central	0	yes	19.828	0.000	EPSD	TCGA;ICGC;COSMIC	9.358	Loss
CMGC_MAPK_ERK1_MAPK3_ST	Q9ULV5	HSF4	P27361	MAPK3	S491	S491P	491	Missense	central	0	yes	19.828	0.000	EPSD	TCGA;COSMIC	9.358	Loss
CMGC_MAPK_ERK1_MAPK3_ST	Q9ULV5	HSF4	P27361	MAPK3	S491	S489G	489	Missense	proximal	-2	no	19.828	18.788	EPSD	TCGA;ICGC;COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q8N122	RPTOR	P27361	MAPK3	S8	L10F	10	Missense	proximal	2	no	16.132	16.105	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q8N122	RPTOR	P27361	MAPK3	S8	L11M	11	Missense	distal	3	no	16.132	16.102	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q8N122	RPTOR	P27361	MAPK3	T706	C713F	713	Missense	distal	7	no	16.131	16.010	EPSD	TCGA	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q8N122	RPTOR	P27361	MAPK3	S711	C713F	713	Missense	proximal	2	no	17.781	17.793	EPSD	TCGA	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q8N122	RPTOR	P27361	MAPK3	S711	R709Q	709	Missense	proximal	-2	no	17.781	17.418	EPSD	TCGA;COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q8N122	RPTOR	P27361	MAPK3	T714	S719F	719	Missense	distal	5	no	15.978	15.553	EPSD	TCGA;ICGC;COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q8N122	RPTOR	P27361	MAPK3	T714	C713F	713	Missense	proximal	-1	no	15.978	16.000	EPSD	TCGA	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q8N122	RPTOR	P27361	MAPK3	T714	R709Q	709	Missense	distal	-5	no	15.978	15.970	EPSD	TCGA;COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q8N122	RPTOR	P27361	MAPK3	S771	E775K	775	Missense	distal	4	no	18.362	18.324	EPSD	TCGA;COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q8N122	RPTOR	P27361	MAPK3	S803	Q810H	810	Missense	distal	7	no	10.000	9.938	EPSD	TCGA;COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q8N122	RPTOR	P27361	MAPK3	S863	T857M	857	Missense	distal	-6	no	17.807	17.554	EPSD;PhosphoSitePlus	TCGA;COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q8N122	RPTOR	P27361	MAPK3	S877	S877F	877	Missense	central	0	yes	16.346	0.000	EPSD	TCGA;COSMIC	9.358	Loss
CMGC_MAPK_ERK1_MAPK3_ST	Q8N122	RPTOR	P27361	MAPK3	S877	P879L	879	Missense	proximal	2	no	16.346	16.325	EPSD	TCGA;COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q8N122	RPTOR	P27361	MAPK3	S881	S877F	877	Missense	distal	-4	no	9.382	9.193	EPSD	TCGA;COSMIC	9.358	Loss
CMGC_MAPK_ERK1_MAPK3_ST	Q8N122	RPTOR	P27361	MAPK3	S881	P879L	879	Missense	proximal	-2	no	9.382	7.998	EPSD	TCGA;COSMIC	9.358	Loss
CMGC_MAPK_ERK1_MAPK3_ST	Q8N122	RPTOR	P27361	MAPK3	S920	R927L	927	Missense	distal	7	no	10.601	10.702	EPSD	TCGA;COSMIC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P49407	ARRB1	P27361	MAPK3	S86	S86L	86	Missense	central	0	yes	10.307	0.000	EPSD	TCGA;ICGC;COSMIC	9.358	Loss
CMGC_MAPK_ERK1_MAPK3_ST	P49407	ARRB1	P27361	MAPK3	T275	N281K	281	Missense	distal	6	no	14.733	14.754	EPSD	TCGA;ICGC;COSMIC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P49407	ARRB1	P27361	MAPK3	T275	C269Y	269	Missense	distal	-6	no	14.733	15.039	EPSD	TCGA;ICGC;COSMIC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P27361	MAPK3	P27361	MAPK3	T17	E18Q	18	Missense	proximal	1	no	8.188	9.492	EPSD	TCGA;ICGC;COSMIC	9.358	Gain
CMGC_MAPK_ERK1_MAPK3_ST	P27361	MAPK3	P27361	MAPK3	S263	L269P	269	Missense	distal	6	no	18.959	19.186	EPSD	TCGA;ICGC;COSMIC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P31645	SLC6A4	P27361	MAPK3	S52	D58N	58	Missense	distal	6	no	17.221	17.169	EPSD	TCGA;ICGC;COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P31645	SLC6A4	P27361	MAPK3	S52	A55T	55	Missense	distal	3	no	17.221	17.252	EPSD	TCGA;ICGC;COSMIC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P31645	SLC6A4	P27361	MAPK3	S52	A55V	55	Missense	distal	3	no	17.221	17.228	EPSD	TCGA;ICGC;COSMIC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P31645	SLC6A4	P27361	MAPK3	S559	L557P	557	Missense	proximal	-2	no	17.046	18.430	EPSD	TCGA;ICGC;COSMIC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P31645	SLC6A4	P27361	MAPK3	T603	P601L	601	Missense	proximal	-2	no	10.235	8.851	EPSD	TCGA;ICGC;COSMIC	9.358	Loss
CMGC_MAPK_ERK1_MAPK3_ST	P31645	SLC6A4	P27361	MAPK3	T603	R596Q	596	Missense	distal	-7	no	10.235	10.234	EPSD	TCGA;ICGC;COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P31645	SLC6A4	P27361	MAPK3	T603	R607C	607	Missense	distal	4	no	10.235	9.878	EPSD	TCGA;ICGC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P31645	SLC6A4	P27361	MAPK3	T603	R596W	596	Missense	distal	-7	no	10.235	10.481	EPSD	TCGA;ICGC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P31645	SLC6A4	P27361	MAPK3	T613	R607C	607	Missense	distal	-6	no	18.182	17.783	EPSD	TCGA;ICGC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P33076	CIITA	P27361	MAPK3	S280	P281A	281	Missense	proximal	1	no	19.345	10.105	PhosphoSitePlus;EPSD	TCGA;COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P33076	CIITA	P27361	MAPK3	S280	T273I	273	Missense	distal	-7	no	19.345	19.460	PhosphoSitePlus;EPSD	TCGA;COSMIC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P33076	CIITA	P27361	MAPK3	S288	R283Q	283	Missense	distal	-5	no	16.051	16.043	EPSD;PhosphoSitePlus	TCGA;COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P33076	CIITA	P27361	MAPK3	S288	P281A	281	Missense	distal	-7	no	16.051	16.163	EPSD;PhosphoSitePlus	TCGA;COSMIC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P33076	CIITA	P27361	MAPK3	S834	T841M	841	Missense	distal	7	no	9.295	9.626	EPSD	TCGA	9.358	Gain
CMGC_MAPK_ERK1_MAPK3_ST	P33076	CIITA	P27361	MAPK3	S834	R832H	832	Missense	proximal	-2	no	9.295	9.467	EPSD	TCGA;ICGC	9.358	Gain
CMGC_MAPK_ERK1_MAPK3_ST	P33076	CIITA	P27361	MAPK3	S942	T940M	940	Missense	proximal	-2	no	9.374	7.606	EPSD	TCGA;COSMIC	9.358	Loss
CMGC_MAPK_ERK1_MAPK3_ST	P33076	CIITA	P27361	MAPK3	S942	S944W	944	Missense	proximal	2	no	9.374	9.301	EPSD	TCGA;COSMIC	9.358	Loss
CMGC_MAPK_ERK1_MAPK3_ST	P33076	CIITA	P27361	MAPK3	S942	S942R	942	Missense	central	0	yes	9.374	0.000	EPSD	TCGA	9.358	Loss
CMGC_MAPK_ERK1_MAPK3_ST	P78347	GTF2I	P27361	MAPK3	S19	R20S	20	Missense	proximal	1	no	9.384	9.831	EPSD	TCGA;ICGC;COSMIC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P78347	GTF2I	P27361	MAPK3	S19	E18K	18	Missense	proximal	-1	no	9.384	9.353	EPSD	TCGA;ICGC;COSMIC	9.358	Loss
CMGC_MAPK_ERK1_MAPK3_ST	P78347	GTF2I	P27361	MAPK3	T24	R20S	20	Missense	distal	-4	no	12.054	12.131	EPSD	TCGA;ICGC;COSMIC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P78347	GTF2I	P27361	MAPK3	T24	L30V	30	Missense	distal	6	no	12.054	11.972	EPSD	TCGA;ICGC;COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P78347	GTF2I	P27361	MAPK3	T24	E18K	18	Missense	distal	-6	no	12.054	11.912	EPSD	TCGA;ICGC;COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P78347	GTF2I	P27361	MAPK3	T24	A29D	29	Missense	distal	5	no	12.054	12.267	EPSD	TCGA;ICGC;COSMIC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P78347	GTF2I	P27361	MAPK3	T24	S28L	28	Missense	distal	4	no	12.054	11.851	EPSD	TCGA;ICGC;COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P78347	GTF2I	P27361	MAPK3	S210	P211A	211	Missense	proximal	1	no	15.908	6.668	EPSD	TCGA;ICGC;COSMIC	9.358	Loss
CMGC_MAPK_ERK1_MAPK3_ST	P78347	GTF2I	P27361	MAPK3	T558	R555I	555	Missense	distal	-3	no	15.496	15.423	EPSD	TCGA;COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P78347	GTF2I	P27361	MAPK3	S620	R619Q	619	Missense	proximal	-1	no	16.076	16.037	EPSD	TCGA;COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P78347	GTF2I	P27361	MAPK3	S620	P617S	617	Missense	distal	-3	no	16.076	16.067	EPSD	TCGA;COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P78347	GTF2I	P27361	MAPK3	S651	I650F	650	Missense	proximal	-1	no	10.634	10.561	EPSD	TCGA;COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P78347	GTF2I	P27361	MAPK3	S971	E969Q	969	Missense	proximal	-2	no	11.455	11.337	EPSD	TCGA	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P78347	GTF2I	P27361	MAPK3	S988	Q989E	989	Missense	proximal	1	no	11.089	9.785	EPSD	TCGA	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q14790	CASP8	P27361	MAPK3	S60	L66V	66	Missense	distal	6	no	9.486	9.404	EPSD	TCGA;COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q14790	CASP8	P27361	MAPK3	S60	L66R	66	Missense	distal	6	no	9.486	9.601	EPSD	TCGA;COSMIC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	O43521	BCL2L11	P27361	MAPK3	S59	P63S	63	Missense	distal	4	no	16.761	16.810	EPSD	TCGA;ICGC;COSMIC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	O43521	BCL2L11	P27361	MAPK3	S69	P63S	63	Missense	distal	-6	no	18.489	18.574	PhosphoSitePlus	TCGA;ICGC;COSMIC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	O43521	BCL2L11	P27361	MAPK3	S69	A68V	68	Missense	proximal	-1	no	18.489	18.539	PhosphoSitePlus	TCGA;ICGC;COSMIC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	O43521	BCL2L11	P27361	MAPK3	S77	S77F	77	Missense	central	0	yes	15.478	0.000	EPSD	TCGA;ICGC;COSMIC	9.358	Loss
CMGC_MAPK_ERK1_MAPK3_ST	O43521	BCL2L11	P27361	MAPK3	S77	R84T	84	Missense	distal	7	no	15.478	15.427	EPSD	TCGA;ICGC;COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	O43521	BCL2L11	P27361	MAPK3	S98	R91Q	91	Missense	distal	-7	no	10.615	10.614	EPSD	TCGA;ICGC;COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	O43521	BCL2L11	P27361	MAPK3	S98	Y96C	96	Missense	proximal	-2	no	10.615	8.408	EPSD	TCGA;ICGC;COSMIC	9.358	Loss
CMGC_MAPK_ERK1_MAPK3_ST	P42229	STAT5A	P27361	MAPK3	S128	E122Q	122	Missense	distal	-6	no	12.917	12.783	EPSD	TCGA;ICGC;COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P42229	STAT5A	P27361	MAPK3	S128	D135E	135	Missense	distal	7	no	12.917	12.915	EPSD	TCGA;COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P42229	STAT5A	P27361	MAPK3	S193	A187S	187	Missense	distal	-6	no	16.457	16.774	EPSD	TCGA;COSMIC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P42229	STAT5A	P27361	MAPK3	S777	R778H	778	Missense	proximal	1	no	9.885	11.630	EPSD	TCGA;COSMIC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P42229	STAT5A	P27361	MAPK3	S777	D776G	776	Missense	proximal	-1	no	9.885	9.866	EPSD	TCGA;COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P42229	STAT5A	P27361	MAPK3	S780	R778H	778	Missense	proximal	-2	no	18.628	18.800	PhosphoSitePlus	TCGA;COSMIC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P42229	STAT5A	P27361	MAPK3	S780	D776G	776	Missense	distal	-4	no	18.628	18.625	PhosphoSitePlus	TCGA;COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q15366	PCBP2	P27361	MAPK3	S90	S85R	85	Missense	distal	-5	no	9.558	9.512	EPSD	TCGA;ICGC;COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q15366	PCBP2	P27361	MAPK3	S90	P97L	97	Missense	distal	7	no	9.558	9.750	EPSD	TCGA;ICGC;COSMIC;GDSC;CCLE	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q15366	PCBP2	P27361	MAPK3	S90	S86Y	86	Missense	distal	-4	no	9.558	9.455	EPSD	TCGA;ICGC;COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q15366	PCBP2	P27361	MAPK3	S90	T88I	88	Missense	proximal	-2	no	9.558	8.705	EPSD	TCGA;ICGC;COSMIC	9.358	Loss
CMGC_MAPK_ERK1_MAPK3_ST	Q15366	PCBP2	P27361	MAPK3	S107	V103M	103	Missense	distal	-4	no	10.101	10.073	EPSD	TCGA;ICGC;COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q15366	PCBP2	P27361	MAPK3	S173	P175L	175	Missense	proximal	2	no	16.839	16.818	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q15366	PCBP2	P27361	MAPK3	S173	L170I	170	Missense	distal	-3	no	16.839	16.803	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q15366	PCBP2	P27361	MAPK3	S173	P175T	175	Missense	proximal	2	no	16.839	16.830	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q15366	PCBP2	P27361	MAPK3	S208	G203D	203	Missense	distal	-5	no	11.745	11.754	EPSD	TCGA;ICGC;COSMIC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q15366	PCBP2	P27361	MAPK3	T213	P220H	220	Missense	distal	7	no	14.340	14.400	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q15366	PCBP2	P27361	MAPK3	S272	I268T	268	Missense	distal	-4	no	17.860	17.961	PhosphoSitePlus;EPSD	TCGA;COSMIC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q8N9N5	BANP	P27361	MAPK3	S19	D17Y	17	Missense	proximal	-2	no	19.122	19.420	EPSD	TCGA;ICGC;COSMIC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q8N9N5	BANP	P27361	MAPK3	S19	L18M	18	Missense	proximal	-1	no	19.122	19.055	EPSD	TCGA;ICGC;COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q8N9N5	BANP	P27361	MAPK3	S90	P95S	95	Missense	distal	5	no	14.270	14.313	EPSD	TCGA;COSMIC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q8N9N5	BANP	P27361	MAPK3	S90	Q93H	93	Missense	distal	3	no	14.270	14.277	EPSD	TCGA;COSMIC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q8N9N5	BANP	P27361	MAPK3	S90	V84I	84	Missense	distal	-6	no	14.270	14.201	EPSD	TCGA	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q8N9N5	BANP	P27361	MAPK3	S100	P95S	95	Missense	distal	-5	no	16.242	16.247	EPSD	TCGA;COSMIC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q8N9N5	BANP	P27361	MAPK3	S100	G99V	99	Missense	proximal	-1	no	16.242	16.224	EPSD	TCGA;COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q8N9N5	BANP	P27361	MAPK3	S100	Q93H	93	Missense	distal	-7	no	16.242	16.232	EPSD	TCGA;COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q8N9N5	BANP	P27361	MAPK3	S334	R335W	335	Missense	proximal	1	no	8.285	9.882	EPSD	TCGA;COSMIC	9.358	Gain
CMGC_MAPK_ERK1_MAPK3_ST	Q8N9N5	BANP	P27361	MAPK3	T337	S340L	340	Missense	distal	3	no	16.081	16.049	PhosphoSitePlus;EPSD	TCGA	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q8N9N5	BANP	P27361	MAPK3	T337	S341F	341	Missense	distal	4	no	16.081	15.666	PhosphoSitePlus;EPSD	TCGA;COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q8N9N5	BANP	P27361	MAPK3	T337	R335W	335	Missense	proximal	-2	no	16.081	14.184	PhosphoSitePlus;EPSD	TCGA;COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q8N9N5	BANP	P27361	MAPK3	T337	N339S	339	Missense	proximal	2	no	16.081	16.098	PhosphoSitePlus;EPSD	TCGA	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q8N9N5	BANP	P27361	MAPK3	T352	P348L	348	Missense	distal	-4	no	14.465	14.352	EPSD;PhosphoSitePlus	TCGA;COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q8N9N5	BANP	P27361	MAPK3	T352	P353S	353	Missense	proximal	1	no	14.465	5.411	EPSD;PhosphoSitePlus	TCGA;COSMIC	9.358	Loss
CMGC_MAPK_ERK1_MAPK3_ST	Q8N9N5	BANP	P27361	MAPK3	T352	P355S	355	Missense	distal	3	no	14.465	14.460	EPSD;PhosphoSitePlus	TCGA;COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q8N9N5	BANP	P27361	MAPK3	T352	T352A	352	Missense	central	0	yes	14.465	0.000	EPSD;PhosphoSitePlus	TCGA;COSMIC	9.358	Loss
CMGC_MAPK_ERK1_MAPK3_ST	Q8N9N5	BANP	P27361	MAPK3	T352	A356T	356	Missense	distal	4	no	14.465	14.683	EPSD;PhosphoSitePlus	TCGA;COSMIC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q8N9N5	BANP	P27361	MAPK3	T352	T352I	352	Missense	central	0	yes	14.465	0.000	EPSD;PhosphoSitePlus	TCGA	9.358	Loss
CMGC_MAPK_ERK1_MAPK3_ST	Q16559	TAL2	P27361	MAPK3	S100	E94Q	94	Missense	distal	-6	no	19.528	19.393	PhosphoSitePlus	TCGA;ICGC;COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q16559	TAL2	P27361	MAPK3	S100	Q97L	97	Missense	distal	-3	no	19.528	19.497	PhosphoSitePlus	TCGA;COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q16559	TAL2	P27361	MAPK3	S100	S100L	100	Missense	central	0	yes	19.528	0.000	PhosphoSitePlus	TCGA;ICGC;COSMIC	9.358	Loss
CMGC_MAPK_ERK1_MAPK3_ST	Q16559	TAL2	P27361	MAPK3	S100	P99S	99	Missense	proximal	-1	no	19.528	19.522	PhosphoSitePlus	TCGA;ICGC;COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q16559	TAL2	P27361	MAPK3	S100	Q97H	97	Missense	distal	-3	no	19.528	19.542	PhosphoSitePlus	TCGA;ICGC;COSMIC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	O00429	DNM1L	P27361	MAPK3	S412	S412L	412	Missense	central	0	yes	10.500	0.000	EPSD	TCGA;COSMIC	9.358	Loss
CMGC_MAPK_ERK1_MAPK3_ST	O00429	DNM1L	P27361	MAPK3	S616	A622V	622	Missense	distal	6	no	18.171	18.258	PhosphoSitePlus	TCGA;COSMIC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	O00429	DNM1L	P27361	MAPK3	S616	G620C	620	Missense	distal	4	no	18.171	17.828	PhosphoSitePlus	TCGA	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	O00429	DNM1L	P27361	MAPK3	S724	A719S	719	Missense	distal	-5	no	10.850	10.949	EPSD	TCGA	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P17542	TAL1	P27361	MAPK3	S172	P171L	171	Missense	proximal	-1	no	14.841	14.747	EPSD	TCGA;COSMIC;GDSC;CCLE	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P17542	TAL1	P27361	MAPK3	S300	D296Y	296	Missense	distal	-4	no	15.182	15.114	EPSD	TCGA;ICGC;COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P17542	TAL1	P27361	MAPK3	S300	T305K	305	Missense	distal	5	no	15.182	15.165	EPSD	TCGA;COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P17542	TAL1	P27361	MAPK3	S300	G297E	297	Missense	distal	-3	no	15.182	15.195	EPSD	TCGA;COSMIC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P17542	TAL1	P27361	MAPK3	S300	S293I	293	Missense	distal	-7	no	15.182	15.373	EPSD	TCGA;COSMIC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P17542	TAL1	P27361	MAPK3	S303	A309V	309	Missense	distal	6	no	11.936	12.024	EPSD	TCGA;COSMIC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P17542	TAL1	P27361	MAPK3	S303	P308H	308	Missense	distal	5	no	11.936	11.871	EPSD	TCGA;COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P17542	TAL1	P27361	MAPK3	S303	A309E	309	Missense	distal	6	no	11.936	12.330	EPSD	TCGA;COSMIC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P17542	TAL1	P27361	MAPK3	S303	D296Y	296	Missense	distal	-7	no	11.936	12.012	EPSD	TCGA;ICGC;COSMIC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P17542	TAL1	P27361	MAPK3	S303	T305K	305	Missense	proximal	2	no	11.936	11.931	EPSD	TCGA;COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P17542	TAL1	P27361	MAPK3	S303	G297E	297	Missense	distal	-6	no	11.936	11.982	EPSD	TCGA;COSMIC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P17542	TAL1	P27361	MAPK3	T313	A309V	309	Missense	distal	-4	no	9.647	9.627	EPSD	TCGA;COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P17542	TAL1	P27361	MAPK3	T313	P308H	308	Missense	distal	-5	no	9.647	9.616	EPSD	TCGA;COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P17542	TAL1	P27361	MAPK3	T313	T313K	313	Missense	central	0	yes	9.647	0.000	EPSD	TCGA;COSMIC	9.358	Loss
CMGC_MAPK_ERK1_MAPK3_ST	P17542	TAL1	P27361	MAPK3	T313	A309E	309	Missense	distal	-4	no	9.647	9.754	EPSD	TCGA;COSMIC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P17542	TAL1	P27361	MAPK3	T313	P319S	319	Missense	distal	6	no	9.647	9.777	EPSD	TCGA;ICGC;COSMIC;CCLE	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P17542	TAL1	P27361	MAPK3	S316	T313K	313	Missense	distal	-3	no	9.898	9.878	EPSD	TCGA;COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P17542	TAL1	P27361	MAPK3	S316	A309E	309	Missense	distal	-7	no	9.898	9.781	EPSD	TCGA;COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P17542	TAL1	P27361	MAPK3	S316	P319S	319	Missense	distal	3	no	9.898	9.894	EPSD	TCGA;ICGC;COSMIC;CCLE	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q13485	SMAD4	P27361	MAPK3	T9	S12R	12	Missense	distal	3	no	14.802	14.780	EPSD	TCGA;ICGC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q13485	SMAD4	P27361	MAPK3	S138	Y133N	133	Missense	distal	-5	no	15.185	15.208	EPSD	TCGA;ICGC;COSMIC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q13485	SMAD4	P27361	MAPK3	S138	H132Y	132	Missense	distal	-6	no	15.185	15.096	EPSD	TCGA;ICGC;COSMIC;GDSC;CCLE	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q13485	SMAD4	P27361	MAPK3	S138	E134K	134	Missense	distal	-4	no	15.185	15.125	EPSD	TCGA;ICGC;COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q13485	SMAD4	P27361	MAPK3	S138	V137A	137	Missense	proximal	-1	no	15.185	15.135	EPSD	TCGA;ICGC;COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q13485	SMAD4	P27361	MAPK3	S138	H132Q	132	Missense	distal	-6	no	15.185	15.199	EPSD	TCGA;ICGC;COSMIC;CCLE	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q13485	SMAD4	P27361	MAPK3	T277	P275T	275	Missense	proximal	-2	no	16.892	15.906	PhosphoSitePlus	TCGA;ICGC;COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q13485	SMAD4	P27361	MAPK3	S504	W509G	509	Missense	distal	5	no	9.251	9.798	EPSD	TCGA;ICGC;COSMIC	9.358	Gain
CMGC_MAPK_ERK1_MAPK3_ST	Q13485	SMAD4	P27361	MAPK3	S504	W509R	509	Missense	distal	5	no	9.251	9.719	EPSD	TCGA;ICGC;COSMIC	9.358	Gain
CMGC_MAPK_ERK1_MAPK3_ST	P00533	EGFR	P27361	MAPK3	S77	E84V	84	Missense	distal	7	no	10.908	11.122	EPSD	TCGA;ICGC;COSMIC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P00533	EGFR	P27361	MAPK3	S77	I82V	82	Missense	distal	5	no	10.908	11.035	EPSD	TCGA;ICGC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P00533	EGFR	P27361	MAPK3	S227	R222C	222	Missense	distal	-5	no	15.963	15.847	EPSD	TCGA;COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P00533	EGFR	P27361	MAPK3	S227	S229C	229	Missense	proximal	2	no	15.963	15.902	EPSD	TCGA;COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P00533	EGFR	P27361	MAPK3	S227	C223Y	223	Missense	distal	-4	no	15.963	16.098	EPSD	TCGA;COSMIC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P00533	EGFR	P27361	MAPK3	S227	R222L	222	Missense	distal	-5	no	15.963	15.949	EPSD	TCGA;COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P00533	EGFR	P27361	MAPK3	S227	S227F	227	Missense	central	0	yes	15.963	0.000	EPSD	TCGA;COSMIC	9.358	Loss
CMGC_MAPK_ERK1_MAPK3_ST	P00533	EGFR	P27361	MAPK3	S227	P228L	228	Missense	proximal	1	no	15.963	6.925	EPSD	TCGA;COSMIC	9.358	Loss
CMGC_MAPK_ERK1_MAPK3_ST	P00533	EGFR	P27361	MAPK3	S227	N234S	234	Missense	distal	7	no	15.963	15.797	EPSD	TCGA;COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P00533	EGFR	P27361	MAPK3	S227	R224H	224	Missense	distal	-3	no	15.963	15.970	EPSD	TCGA;COSMIC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P00533	EGFR	P27361	MAPK3	S229	R222C	222	Missense	distal	-7	no	10.196	10.383	EPSD	TCGA;COSMIC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P00533	EGFR	P27361	MAPK3	S229	S229C	229	Missense	central	0	yes	10.196	0.000	EPSD	TCGA;COSMIC	9.358	Loss
CMGC_MAPK_ERK1_MAPK3_ST	P00533	EGFR	P27361	MAPK3	S229	C223Y	223	Missense	distal	-6	no	10.196	10.502	EPSD	TCGA;COSMIC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P00533	EGFR	P27361	MAPK3	S229	R222L	222	Missense	distal	-7	no	10.196	10.258	EPSD	TCGA;COSMIC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P00533	EGFR	P27361	MAPK3	S229	S227F	227	Missense	proximal	-2	no	10.196	8.896	EPSD	TCGA;COSMIC	9.358	Loss
CMGC_MAPK_ERK1_MAPK3_ST	P00533	EGFR	P27361	MAPK3	S229	P228L	228	Missense	proximal	-1	no	10.196	10.102	EPSD	TCGA;COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P00533	EGFR	P27361	MAPK3	S229	N234S	234	Missense	distal	5	no	10.196	10.319	EPSD	TCGA;COSMIC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P00533	EGFR	P27361	MAPK3	S229	R224H	224	Missense	distal	-5	no	10.196	10.206	EPSD	TCGA;COSMIC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P00533	EGFR	P27361	MAPK3	S511	P512S	512	Missense	proximal	1	no	15.023	5.970	EPSD	TCGA;COSMIC	9.358	Loss
CMGC_MAPK_ERK1_MAPK3_ST	P00533	EGFR	P27361	MAPK3	T693	P699L	699	Missense	distal	6	no	18.879	18.652	PhosphoSitePlus	TCGA;COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P00533	EGFR	P27361	MAPK3	S752	I759N	759	Missense	distal	7	no	15.913	15.680	EPSD	TCGA;COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P00533	EGFR	P27361	MAPK3	S752	K754E	754	Missense	proximal	2	no	15.913	15.920	EPSD	TCGA;COSMIC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P00533	EGFR	P27361	MAPK3	S752	K754I	754	Missense	proximal	2	no	15.913	15.894	EPSD	TCGA;COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P00533	EGFR	P27361	MAPK3	S752	P753L	753	Missense	proximal	1	no	15.913	6.874	EPSD	TCGA;COSMIC	9.358	Loss
CMGC_MAPK_ERK1_MAPK3_ST	P00533	EGFR	P27361	MAPK3	S752	P753S	753	Missense	proximal	1	no	15.913	6.859	EPSD	TCGA;COSMIC;GDSC;CCLE	9.358	Loss
CMGC_MAPK_ERK1_MAPK3_ST	P00533	EGFR	P27361	MAPK3	S991	F997V	997	Missense	distal	6	no	16.779	17.054	EPSD	TCGA;COSMIC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P00533	EGFR	P27361	MAPK3	S1026	T1032S	1032	Missense	distal	6	no	16.359	16.514	EPSD	TCGA;COSMIC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P00533	EGFR	P27361	MAPK3	S1026	P1019L	1019	Missense	distal	-7	no	16.359	16.466	EPSD	TCGA;COSMIC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P00533	EGFR	P27361	MAPK3	S1026	R1031Q	1031	Missense	distal	5	no	16.359	16.358	EPSD	TCGA;COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P00533	EGFR	P27361	MAPK3	S1028	T1032S	1032	Missense	distal	4	no	9.954	10.066	EPSD	TCGA;COSMIC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P00533	EGFR	P27361	MAPK3	T1032	R1031Q	1031	Missense	proximal	-1	no	13.788	13.749	EPSD	TCGA;COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P00533	EGFR	P27361	MAPK3	T1085	E1079K	1079	Missense	distal	-6	no	10.911	10.769	EPSD	TCGA;COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P00533	EGFR	P27361	MAPK3	T1085	D1084N	1084	Missense	proximal	-1	no	10.911	10.909	EPSD	TCGA	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P00533	EGFR	P27361	MAPK3	S1153	D1152N	1152	Missense	proximal	-1	no	15.338	15.335	EPSD	TCGA;ICGC;COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P00533	EGFR	P27361	MAPK3	S1153	T1150S	1150	Missense	distal	-3	no	15.338	15.368	EPSD	TCGA;ICGC;COSMIC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P00533	EGFR	P27361	MAPK3	S1153	F1151L	1151	Missense	proximal	-2	no	15.338	16.329	EPSD	TCGA;ICGC;COSMIC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P00533	EGFR	P27361	MAPK3	S1153	V1147A	1147	Missense	distal	-6	no	15.338	15.351	EPSD	TCGA;ICGC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P00533	EGFR	P27361	MAPK3	S1204	A1201V	1201	Missense	distal	-3	no	11.806	11.825	EPSD	TCGA;ICGC;COSMIC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P00533	EGFR	P27361	MAPK3	S1205	A1201V	1201	Missense	distal	-4	no	10.816	10.796	EPSD	TCGA;ICGC;COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P63000	RAC1	P27361	MAPK3	S71	P69S	69	Missense	proximal	-2	no	11.073	9.997	EPSD	TCGA;ICGC;COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P63000	RAC1	P27361	MAPK3	S71	P73L	73	Missense	proximal	2	no	11.073	11.051	EPSD	TCGA;ICGC;COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P63000	RAC1	P27361	MAPK3	S71	R68S	68	Missense	distal	-3	no	11.073	11.110	EPSD	TCGA;ICGC;COSMIC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P63000	RAC1	P27361	MAPK3	S71	R68H	68	Missense	distal	-3	no	11.073	11.079	EPSD	TCGA;ICGC;COSMIC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P63000	RAC1	P27361	MAPK3	S71	R68C	68	Missense	distal	-3	no	11.073	10.933	EPSD	TCGA;ICGC;COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P63000	RAC1	P27361	MAPK3	S71	S71F	71	Missense	central	0	yes	11.073	0.000	EPSD	TCGA;ICGC;COSMIC	9.358	Loss
CMGC_MAPK_ERK1_MAPK3_ST	P63000	RAC1	P27361	MAPK3	T108	P106L	106	Missense	proximal	-2	no	16.930	15.546	PhosphoSitePlus	TCGA;COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	O60244	MED14	P27361	MAPK3	S151	P155S	155	Missense	distal	4	no	10.021	10.070	EPSD	TCGA;ICGC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	O60244	MED14	P27361	MAPK3	S151	A153T	153	Missense	proximal	2	no	10.021	10.048	EPSD	TCGA;ICGC;COSMIC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	O60244	MED14	P27361	MAPK3	S986	P984H	984	Missense	proximal	-2	no	17.048	15.820	PhosphoSitePlus	TCGA;ICGC;COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	O60244	MED14	P27361	MAPK3	S986	P987S	987	Missense	proximal	1	no	17.048	7.994	PhosphoSitePlus	TCGA;ICGC;COSMIC	9.358	Loss
CMGC_MAPK_ERK1_MAPK3_ST	O60244	MED14	P27361	MAPK3	S1061	L1057W	1057	Missense	distal	-4	no	13.717	13.572	EPSD	TCGA;ICGC;COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	O60244	MED14	P27361	MAPK3	S1061	A1063V	1063	Missense	proximal	2	no	13.717	13.730	EPSD	TCGA;ICGC;COSMIC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	O60244	MED14	P27361	MAPK3	S1064	L1057W	1057	Missense	distal	-7	no	11.437	11.621	EPSD	TCGA;ICGC;COSMIC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	O60244	MED14	P27361	MAPK3	S1064	A1063V	1063	Missense	proximal	-1	no	11.437	11.486	EPSD	TCGA;ICGC;COSMIC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	O60244	MED14	P27361	MAPK3	S1086	A1082T	1082	Missense	distal	-4	no	15.169	15.242	EPSD	TCGA;ICGC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	O60244	MED14	P27361	MAPK3	S1095	P1096T	1096	Missense	proximal	1	no	18.957	10.080	EPSD	TCGA;ICGC;COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	O60244	MED14	P27361	MAPK3	S1095	P1096S	1096	Missense	proximal	1	no	18.957	9.904	EPSD	TCGA;ICGC;COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	O60244	MED14	P27361	MAPK3	S1101	P1096T	1096	Missense	distal	-5	no	14.180	14.169	EPSD	TCGA;ICGC;COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	O60244	MED14	P27361	MAPK3	S1101	A1106V	1106	Missense	distal	5	no	14.180	14.168	EPSD	TCGA	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	O60244	MED14	P27361	MAPK3	S1101	P1096S	1096	Missense	distal	-5	no	14.180	14.185	EPSD	TCGA;ICGC;COSMIC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	O60244	MED14	P27361	MAPK3	S1112	A1106V	1106	Missense	distal	-6	no	16.484	16.471	EPSD	TCGA	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	O60244	MED14	P27361	MAPK3	S1119	R1123H	1123	Missense	distal	4	no	14.917	14.923	EPSD	TCGA;ICGC;COSMIC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	O60244	MED14	P27361	MAPK3	S1128	R1123H	1123	Missense	distal	-5	no	16.417	16.427	EPSD	TCGA;ICGC;COSMIC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	O60244	MED14	P27361	MAPK3	S1136	V1138A	1138	Missense	proximal	2	no	16.122	16.109	EPSD	TCGA;ICGC;COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	O60244	MED14	P27361	MAPK3	S1136	P1137S	1137	Missense	proximal	1	no	16.122	7.069	EPSD	TCGA;ICGC	9.358	Loss
CMGC_MAPK_ERK1_MAPK3_ST	O60244	MED14	P27361	MAPK3	S1142	G1148E	1148	Missense	distal	6	no	9.283	9.383	EPSD	TCGA;ICGC;COSMIC	9.358	Gain
CMGC_MAPK_ERK1_MAPK3_ST	O60244	MED14	P27361	MAPK3	S1144	V1138A	1138	Missense	distal	-6	no	16.725	16.738	EPSD	TCGA;ICGC;COSMIC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	O60244	MED14	P27361	MAPK3	S1144	G1148E	1148	Missense	distal	4	no	16.725	16.785	EPSD	TCGA;ICGC;COSMIC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	O60244	MED14	P27361	MAPK3	S1144	P1137S	1137	Missense	distal	-7	no	16.725	16.687	EPSD	TCGA;ICGC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	O60244	MED14	P27361	MAPK3	S1151	G1148E	1148	Missense	distal	-3	no	9.953	9.966	EPSD	TCGA;ICGC;COSMIC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	O60244	MED14	P27361	MAPK3	S1151	T1153I	1153	Missense	proximal	2	no	9.953	9.929	EPSD	TCGA;ICGC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	O60244	MED14	P27361	MAPK3	S1254	T1260M	1260	Missense	distal	6	no	15.993	15.499	EPSD	TCGA	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	O60244	MED14	P27361	MAPK3	S1254	N1258S	1258	Missense	distal	4	no	15.993	16.140	EPSD	TCGA;ICGC;COSMIC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	O60244	MED14	P27361	MAPK3	S1254	V1251L	1251	Missense	distal	-3	no	15.993	15.990	EPSD	TCGA;ICGC;COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	O60244	MED14	P27361	MAPK3	T1354	P1347L	1347	Missense	distal	-7	no	17.503	17.610	EPSD	TCGA;ICGC;COSMIC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	O60244	MED14	P27361	MAPK3	T1354	T1354M	1354	Missense	central	0	yes	17.503	0.000	EPSD	TCGA;ICGC;COSMIC	9.358	Loss
CMGC_MAPK_ERK1_MAPK3_ST	O60244	MED14	P27361	MAPK3	T1354	V1358A	1358	Missense	distal	4	no	17.503	17.395	EPSD	TCGA;ICGC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P61978	HNRNPK	P27361	MAPK3	S116	P117L	117	Missense	proximal	1	no	16.938	7.900	EPSD	TCGA;ICGC	9.358	Loss
CMGC_MAPK_ERK1_MAPK3_ST	P61978	HNRNPK	P27361	MAPK3	S216	R221H	221	Missense	distal	5	no	14.264	14.300	EPSD	TCGA;ICGC;COSMIC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P61978	HNRNPK	P27361	MAPK3	S284	M283V	283	Missense	proximal	-1	no	16.461	16.532	PhosphoSitePlus;EPSD	TCGA;ICGC;COSMIC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P61978	HNRNPK	P27361	MAPK3	S353	S355L	355	Missense	proximal	2	no	16.088	16.064	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P61978	HNRNPK	P27361	MAPK3	S353	E356D	356	Missense	distal	3	no	16.088	16.090	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P61978	HNRNPK	P27361	MAPK3	S353	E356A	356	Missense	distal	3	no	16.088	16.057	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P61978	HNRNPK	P27361	MAPK3	S379	A374S	374	Missense	distal	-5	no	10.614	10.713	EPSD	TCGA;ICGC;COSMIC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P61978	HNRNPK	P27361	MAPK3	S379	D382N	382	Missense	distal	3	no	10.614	10.604	EPSD	TCGA;ICGC;COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P61978	HNRNPK	P27361	MAPK3	S379	L383I	383	Missense	distal	4	no	10.614	10.477	EPSD	TCGA;ICGC;COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P61978	HNRNPK	P27361	MAPK3	S379	R377C	377	Missense	proximal	-2	no	10.614	8.498	EPSD	TCGA;ICGC;COSMIC	9.358	Loss
CMGC_MAPK_ERK1_MAPK3_ST	P61978	HNRNPK	P27361	MAPK3	T440	R433L	433	Missense	distal	-7	no	11.582	11.644	EPSD	TCGA;ICGC;COSMIC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P29966	MARCKS	P27361	MAPK3	S27	P28L	28	Missense	proximal	1	no	17.186	8.148	EPSD	TCGA;ICGC;COSMIC	9.358	Loss
CMGC_MAPK_ERK1_MAPK3_ST	P29966	MARCKS	P27361	MAPK3	S27	S29F	29	Missense	proximal	2	no	17.186	17.136	EPSD	TCGA;ICGC;COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P29966	MARCKS	P27361	MAPK3	S308	A306S	306	Missense	proximal	-2	no	8.368	9.642	EPSD	TCGA;ICGC;COSMIC	9.358	Gain
CMGC_MAPK_ERK1_MAPK3_ST	P29966	MARCKS	P27361	MAPK3	S314	S308L	308	Missense	distal	-6	no	11.578	11.246	EPSD	TCGA;ICGC;COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P29966	MARCKS	P27361	MAPK3	S314	E320K	320	Missense	distal	6	no	11.578	11.502	EPSD	TCGA;ICGC;COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	O43524	FOXO3	P27361	MAPK3	S161	N159H	159	Missense	proximal	-2	no	10.249	11.041	EPSD	TCGA	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	O43524	FOXO3	P27361	MAPK3	S161	L165P	165	Missense	distal	4	no	10.249	10.403	EPSD	TCGA;ICGC;COSMIC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	O43524	FOXO3	P27361	MAPK3	S294	S299I	299	Missense	distal	5	no	18.649	18.256	PhosphoSitePlus;EPSD	TCGA;ICGC;COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	O43524	FOXO3	P27361	MAPK3	S294	R298C	298	Missense	distal	4	no	18.649	18.292	PhosphoSitePlus;EPSD	TCGA;ICGC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	O43524	FOXO3	P27361	MAPK3	S294	G293D	293	Missense	proximal	-1	no	18.649	18.668	PhosphoSitePlus;EPSD	TCGA;ICGC;COSMIC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	O43524	FOXO3	P27361	MAPK3	S299	L303M	303	Missense	distal	4	no	9.609	9.434	EPSD	TCGA;ICGC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	O43524	FOXO3	P27361	MAPK3	S299	A305V	305	Missense	distal	6	no	9.609	9.696	EPSD	TCGA;ICGC;COSMIC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	O43524	FOXO3	P27361	MAPK3	S299	S299I	299	Missense	central	0	yes	9.609	0.000	EPSD	TCGA;ICGC;COSMIC	9.358	Loss
CMGC_MAPK_ERK1_MAPK3_ST	O43524	FOXO3	P27361	MAPK3	S299	R298C	298	Missense	proximal	-1	no	9.609	9.424	EPSD	TCGA;ICGC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	O43524	FOXO3	P27361	MAPK3	S299	G293D	293	Missense	distal	-6	no	9.609	9.610	EPSD	TCGA;ICGC;COSMIC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	O43524	FOXO3	P27361	MAPK3	S325	R323L	323	Missense	proximal	-2	no	15.988	16.004	EPSD	TCGA;ICGC;COSMIC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	O43524	FOXO3	P27361	MAPK3	S325	M328I	328	Missense	distal	3	no	15.988	15.999	EPSD	TCGA;ICGC;COSMIC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	O43524	FOXO3	P27361	MAPK3	S344	A341V	341	Missense	distal	-3	no	17.722	17.741	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	O43524	FOXO3	P27361	MAPK3	S344	D340G	340	Missense	distal	-4	no	17.722	17.718	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	O43524	FOXO3	P27361	MAPK3	S355	C362F	362	Missense	distal	7	no	16.937	16.816	EPSD	TCGA;ICGC;COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	O43524	FOXO3	P27361	MAPK3	S402	P397S	397	Missense	distal	-5	no	15.143	15.148	EPSD	TCGA;ICGC;COSMIC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	O43524	FOXO3	P27361	MAPK3	S402	P397L	397	Missense	distal	-5	no	15.143	15.089	EPSD	TCGA;ICGC;COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	O43524	FOXO3	P27361	MAPK3	S402	S402L	402	Missense	central	0	yes	15.143	0.000	EPSD	TCGA;ICGC;COSMIC	9.358	Loss
CMGC_MAPK_ERK1_MAPK3_ST	O43524	FOXO3	P27361	MAPK3	S413	S412C	412	Missense	proximal	-1	no	9.925	9.698	EPSD	TCGA;ICGC;COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	O43524	FOXO3	P27361	MAPK3	S425	L423M	423	Missense	proximal	-2	no	16.864	15.494	EPSD;PhosphoSitePlus	TCGA;ICGC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	O43524	FOXO3	P27361	MAPK3	S425	S425F	425	Missense	central	0	yes	16.864	0.000	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	9.358	Loss
CMGC_MAPK_ERK1_MAPK3_ST	O43524	FOXO3	P27361	MAPK3	S429	G436R	436	Missense	distal	7	no	10.656	10.686	EPSD	TCGA;ICGC;COSMIC;GDSC;CCLE	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	O43524	FOXO3	P27361	MAPK3	S429	L423M	423	Missense	distal	-6	no	10.656	10.566	EPSD	TCGA;ICGC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	O43524	FOXO3	P27361	MAPK3	S429	S425F	425	Missense	distal	-4	no	10.656	10.467	EPSD	TCGA;ICGC;COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	O43524	FOXO3	P27361	MAPK3	S429	V434M	434	Missense	distal	5	no	10.656	10.531	EPSD	TCGA;ICGC;COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	O43524	FOXO3	P27361	MAPK3	S446	Q449H	449	Missense	distal	3	no	15.312	15.320	EPSD	TCGA;ICGC;COSMIC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	O43524	FOXO3	P27361	MAPK3	S574	M580I	580	Missense	distal	6	no	15.818	15.898	EPSD	TCGA;ICGC;COSMIC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	O43524	FOXO3	P27361	MAPK3	S667	A665S	665	Missense	proximal	-2	no	11.953	13.228	EPSD	TCGA;ICGC;COSMIC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	O43524	FOXO3	P27361	MAPK3	S667	S669R	669	Missense	proximal	2	no	11.953	11.941	EPSD	TCGA;ICGC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	O43524	FOXO3	P27361	MAPK3	S669	A665S	665	Missense	distal	-4	no	11.016	11.148	EPSD	TCGA;ICGC;COSMIC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	O43524	FOXO3	P27361	MAPK3	S669	S669R	669	Missense	central	0	yes	11.016	0.000	EPSD	TCGA;ICGC	9.358	Loss
CMGC_MAPK_ERK1_MAPK3_ST	Q13115	DUSP4	P27361	MAPK3	S112	I106V	106	Missense	distal	-6	no	17.462	17.530	EPSD	TCGA;ICGC;COSMIC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q13115	DUSP4	P27361	MAPK3	S318	S315R	315	Missense	distal	-3	no	15.499	15.461	EPSD	TCGA;ICGC;COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q13115	DUSP4	P27361	MAPK3	S318	S318L	318	Missense	central	0	yes	15.499	0.000	EPSD	TCGA;ICGC;COSMIC	9.358	Loss
CMGC_MAPK_ERK1_MAPK3_ST	Q13115	DUSP4	P27361	MAPK3	S318	P319S	319	Missense	proximal	1	no	15.499	6.445	EPSD	TCGA;ICGC;COSMIC	9.358	Loss
CMGC_MAPK_ERK1_MAPK3_ST	Q13115	DUSP4	P27361	MAPK3	S318	R313C	313	Missense	distal	-5	no	15.499	15.383	EPSD	TCGA;ICGC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q13115	DUSP4	P27361	MAPK3	S345	S338F	338	Missense	distal	-7	no	15.420	15.639	EPSD	TCGA;ICGC;COSMIC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q13115	DUSP4	P27361	MAPK3	S345	S347L	347	Missense	proximal	2	no	15.420	15.397	EPSD	TCGA;ICGC;COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q13115	DUSP4	P27361	MAPK3	T356	R353Q	353	Missense	distal	-3	no	13.385	13.378	EPSD	TCGA;ICGC;COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q13115	DUSP4	P27361	MAPK3	T359	R353Q	353	Missense	distal	-6	no	16.806	16.816	EPSD	TCGA;ICGC;COSMIC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q13115	DUSP4	P27361	MAPK3	S367	S371F	371	Missense	distal	4	no	11.751	11.337	EPSD	TCGA;ICGC;COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q13115	DUSP4	P27361	MAPK3	S367	S367R	367	Missense	central	0	yes	11.751	0.000	EPSD	TCGA;ICGC;COSMIC	9.358	Loss
CMGC_MAPK_ERK1_MAPK3_ST	Q13115	DUSP4	P27361	MAPK3	S371	S371F	371	Missense	central	0	yes	10.009	0.000	EPSD	TCGA;ICGC;COSMIC	9.358	Loss
CMGC_MAPK_ERK1_MAPK3_ST	Q13115	DUSP4	P27361	MAPK3	S371	S367R	367	Missense	distal	-4	no	10.009	9.932	EPSD	TCGA;ICGC;COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q13115	DUSP4	P27361	MAPK3	S376	S371F	371	Missense	distal	-5	no	9.397	9.263	EPSD	TCGA;ICGC;COSMIC	9.358	Loss
CMGC_MAPK_ERK1_MAPK3_ST	Q9UHB6	LIMA1	P27361	MAPK3	S4	S3L	3	Missense	proximal	-1	no	16.033	15.944	EPSD	TCGA;ICGC;COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q9UHB6	LIMA1	P27361	MAPK3	S4	E2K	2	Missense	proximal	-2	no	16.033	15.339	EPSD	TCGA;ICGC;COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q9UHB6	LIMA1	P27361	MAPK3	S132	P134L	134	Missense	proximal	2	no	15.907	15.885	EPSD	TCGA;COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q9UHB6	LIMA1	P27361	MAPK3	S132	R127G	127	Missense	distal	-5	no	15.907	15.909	EPSD	TCGA;ICGC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q9UHB6	LIMA1	P27361	MAPK3	S132	R127K	127	Missense	distal	-5	no	15.907	15.906	EPSD	TCGA;ICGC;COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q9UHB6	LIMA1	P27361	MAPK3	S228	D233N	233	Missense	distal	5	no	9.401	9.320	EPSD	TCGA;COSMIC	9.358	Loss
CMGC_MAPK_ERK1_MAPK3_ST	Q9UHB6	LIMA1	P27361	MAPK3	T337	R335C	335	Missense	proximal	-2	no	14.391	12.275	EPSD	TCGA	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q9UHB6	LIMA1	P27361	MAPK3	T337	P338S	338	Missense	proximal	1	no	14.391	5.338	EPSD	TCGA;COSMIC	9.358	Loss
CMGC_MAPK_ERK1_MAPK3_ST	Q9UHB6	LIMA1	P27361	MAPK3	T337	E340K	340	Missense	distal	3	no	14.391	14.380	EPSD	TCGA;COSMIC;GDSC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q9UHB6	LIMA1	P27361	MAPK3	S374	S374N	374	Missense	central	0	yes	16.594	0.000	PhosphoSitePlus;EPSD	TCGA;COSMIC	9.358	Loss
CMGC_MAPK_ERK1_MAPK3_ST	P24941	CDK2	P27361	MAPK3	T221	D223Y	223	Missense	proximal	2	no	17.340	17.330	EPSD	TCGA;GDSC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q05209	PTPN12	P27361	MAPK3	T81	R74Q	74	Missense	distal	-7	no	15.493	15.492	EPSD	TCGA;ICGC;COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q05209	PTPN12	P27361	MAPK3	T81	D85N	85	Missense	distal	4	no	15.493	15.466	EPSD	TCGA;ICGC;COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q05209	PTPN12	P27361	MAPK3	S332	D331N	331	Missense	proximal	-1	no	17.090	17.088	EPSD	TCGA;COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q05209	PTPN12	P27361	MAPK3	T367	H360Y	360	Missense	distal	-7	no	13.676	13.723	EPSD	TCGA;COSMIC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q05209	PTPN12	P27361	MAPK3	S449	L443F	443	Missense	distal	-6	no	9.846	9.711	EPSD	TCGA;COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q05209	PTPN12	P27361	MAPK3	S449	G452V	452	Missense	distal	3	no	9.846	9.824	EPSD	TCGA	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q05209	PTPN12	P27361	MAPK3	S468	K474T	474	Missense	distal	6	no	17.703	17.756	EPSD	TCGA	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q05209	PTPN12	P27361	MAPK3	T509	N504D	504	Missense	distal	-5	no	15.251	15.257	EPSD	TCGA;COSMIC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q05209	PTPN12	P27361	MAPK3	T519	R525C	525	Missense	distal	6	no	14.140	13.515	EPSD	TCGA;COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q05209	PTPN12	P27361	MAPK3	S537	E530D	530	Missense	distal	-7	no	10.914	10.924	EPSD	TCGA	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q05209	PTPN12	P27361	MAPK3	T569	Q575K	575	Missense	distal	6	no	16.217	16.321	EPSD	TCGA;COSMIC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q05209	PTPN12	P27361	MAPK3	S571	Q575K	575	Missense	distal	4	no	16.653	16.705	PhosphoSitePlus	TCGA;COSMIC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q05209	PTPN12	P27361	MAPK3	T578	Q575K	575	Missense	distal	-3	no	13.705	13.700	EPSD	TCGA;COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q05209	PTPN12	P27361	MAPK3	T578	D585N	585	Missense	distal	7	no	13.705	13.765	EPSD	TCGA;COSMIC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q05209	PTPN12	P27361	MAPK3	S588	D585N	585	Missense	distal	-3	no	16.520	16.499	EPSD	TCGA;COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q05209	PTPN12	P27361	MAPK3	T593	T598I	598	Missense	distal	5	no	14.354	14.096	EPSD	TCGA;COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q05209	PTPN12	P27361	MAPK3	S596	T598I	598	Missense	proximal	2	no	10.282	10.258	EPSD	TCGA;COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q05209	PTPN12	P27361	MAPK3	S673	P678L	678	Missense	distal	5	no	15.757	15.530	EPSD	TCGA;COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q05209	PTPN12	P27361	MAPK3	S673	R680I	680	Missense	distal	7	no	15.757	15.986	EPSD	TCGA;COSMIC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q05209	PTPN12	P27361	MAPK3	T681	V686L	686	Missense	distal	5	no	13.665	13.661	EPSD	TCGA	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q05209	PTPN12	P27361	MAPK3	T681	P678L	678	Missense	distal	-3	no	13.665	13.581	EPSD	TCGA;COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q05209	PTPN12	P27361	MAPK3	T681	E683A	683	Missense	proximal	2	no	13.665	13.635	EPSD	TCGA;COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q05209	PTPN12	P27361	MAPK3	T681	E683G	683	Missense	proximal	2	no	13.665	13.657	EPSD	TCGA	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q05209	PTPN12	P27361	MAPK3	T681	R680I	680	Missense	proximal	-1	no	13.665	13.575	EPSD	TCGA;COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q05209	PTPN12	P27361	MAPK3	S684	V686L	686	Missense	proximal	2	no	12.824	12.826	EPSD	TCGA	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q05209	PTPN12	P27361	MAPK3	S684	P678L	678	Missense	distal	-6	no	12.824	12.577	EPSD	TCGA;COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q05209	PTPN12	P27361	MAPK3	S684	E683A	683	Missense	proximal	-1	no	12.824	12.715	EPSD	TCGA;COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q05209	PTPN12	P27361	MAPK3	S684	E683G	683	Missense	proximal	-1	no	12.824	12.783	EPSD	TCGA	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q05209	PTPN12	P27361	MAPK3	S684	R680I	680	Missense	distal	-4	no	12.824	12.742	EPSD	TCGA;COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q05209	PTPN12	P27361	MAPK3	T693	V686L	686	Missense	distal	-7	no	14.867	14.862	EPSD	TCGA	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q05209	PTPN12	P27361	MAPK3	T693	S700T	700	Missense	distal	7	no	14.867	14.985	EPSD	TCGA;COSMIC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P16949	STMN1	P27361	MAPK3	S25	S31Y	31	Missense	distal	6	no	20.581	20.198	PhosphoSitePlus;EPSD	TCGA;COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P16949	STMN1	P27361	MAPK3	S25	S28P	28	Missense	distal	3	no	20.581	20.585	PhosphoSitePlus;EPSD	TCGA;ICGC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P16949	STMN1	P27361	MAPK3	S25	K29I	29	Missense	distal	4	no	20.581	20.378	PhosphoSitePlus;EPSD	TCGA;ICGC;COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P16949	STMN1	P27361	MAPK3	S28	K29I	29	Missense	proximal	1	no	2.642	10.288	EPSD	TCGA;ICGC;COSMIC	9.358	Gain
CMGC_MAPK_ERK1_MAPK3_ST	P16949	STMN1	P27361	MAPK3	S38	S31Y	31	Missense	distal	-7	no	17.700	17.818	EPSD;PhosphoSitePlus	TCGA;COSMIC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P16949	STMN1	P27361	MAPK3	S38	P39S	39	Missense	proximal	1	no	17.700	8.646	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	9.358	Loss
CMGC_MAPK_ERK1_MAPK3_ST	Q9UKX7	NUP50	P27361	MAPK3	S141	L145F	145	Missense	distal	4	no	9.603	9.392	EPSD	TCGA;COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q9UKX7	NUP50	P27361	MAPK3	S142	L145F	145	Missense	distal	3	no	11.541	11.509	EPSD	TCGA;COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q9UKX7	NUP50	P27361	MAPK3	S221	P222A	222	Missense	proximal	1	no	17.386	8.147	EPSD;PhosphoSitePlus	TCGA;COSMIC	9.358	Loss
CMGC_MAPK_ERK1_MAPK3_ST	Q9UKX7	NUP50	P27361	MAPK3	S221	E218V	218	Missense	distal	-3	no	17.386	17.334	EPSD;PhosphoSitePlus	TCGA;COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q9UKX7	NUP50	P27361	MAPK3	S270	G265V	265	Missense	distal	-5	no	10.911	10.878	EPSD	TCGA;COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q9UKX7	NUP50	P27361	MAPK3	S270	K275R	275	Missense	distal	5	no	10.911	10.919	EPSD	TCGA;COSMIC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q9UKX7	NUP50	P27361	MAPK3	S315	S314A	314	Missense	proximal	-1	no	15.216	15.082	PhosphoSitePlus;EPSD	TCGA;COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q15746	MYLK	P27361	MAPK3	S259	N257K	257	Missense	proximal	-2	no	9.463	9.143	EPSD	TCGA;ICGC;COSMIC	9.358	Loss
CMGC_MAPK_ERK1_MAPK3_ST	Q15746	MYLK	P27361	MAPK3	S299	A292T	292	Missense	distal	-7	no	13.189	13.115	EPSD	TCGA;ICGC;COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q15746	MYLK	P27361	MAPK3	S299	K295N	295	Missense	distal	-4	no	13.189	13.211	EPSD	TCGA;ICGC;COSMIC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q15746	MYLK	P27361	MAPK3	S328	T331M	331	Missense	distal	3	no	15.316	15.268	EPSD	TCGA;ICGC;COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q15746	MYLK	P27361	MAPK3	T335	T331M	331	Missense	distal	-4	no	15.827	15.705	EPSD	TCGA;ICGC;COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q15746	MYLK	P27361	MAPK3	T335	T341N	341	Missense	distal	6	no	15.827	15.753	EPSD	TCGA;ICGC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q15746	MYLK	P27361	MAPK3	S365	R371K	371	Missense	distal	6	no	17.290	17.324	EPSD	TCGA;ICGC;COSMIC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q15746	MYLK	P27361	MAPK3	S515	S518G	518	Missense	distal	3	no	9.561	9.546	EPSD	TCGA;ICGC;COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q15746	MYLK	P27361	MAPK3	S515	S517F	517	Missense	proximal	2	no	9.561	9.511	EPSD	TCGA;ICGC;COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q15746	MYLK	P27361	MAPK3	S947	D952N	952	Missense	distal	5	no	16.192	16.112	EPSD	TCGA;ICGC;COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q15746	MYLK	P27361	MAPK3	S947	E940Q	940	Missense	distal	-7	no	16.192	16.242	EPSD	TCGA;ICGC;COSMIC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q15746	MYLK	P27361	MAPK3	S947	D952A	952	Missense	distal	5	no	16.192	15.979	EPSD	TCGA;ICGC;COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q15746	MYLK	P27361	MAPK3	S947	E942K	942	Missense	distal	-5	no	16.192	16.181	EPSD	TCGA;ICGC;COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q15746	MYLK	P27361	MAPK3	S947	R954C	954	Missense	distal	7	no	16.192	16.635	EPSD	TCGA;ICGC;COSMIC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q15746	MYLK	P27361	MAPK3	S947	E940D	940	Missense	distal	-7	no	16.192	16.203	EPSD	TCGA;ICGC;COSMIC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q15746	MYLK	P27361	MAPK3	T978	P979L	979	Missense	proximal	1	no	18.294	9.256	EPSD	TCGA;ICGC;COSMIC	9.358	Loss
CMGC_MAPK_ERK1_MAPK3_ST	Q15746	MYLK	P27361	MAPK3	T978	R982C	982	Missense	distal	4	no	18.294	17.937	EPSD	TCGA;ICGC;COSMIC;GDSC;CCLE	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q15746	MYLK	P27361	MAPK3	S1208	R1204W	1204	Missense	distal	-4	no	9.454	9.246	EPSD	TCGA;ICGC;COSMIC	9.358	Loss
CMGC_MAPK_ERK1_MAPK3_ST	Q15746	MYLK	P27361	MAPK3	S1208	V1213M	1213	Missense	distal	5	no	9.454	9.330	EPSD	TCGA;ICGC;COSMIC;GDSC	9.358	Loss
CMGC_MAPK_ERK1_MAPK3_ST	Q15746	MYLK	P27361	MAPK3	S1208	R1204Q	1204	Missense	distal	-4	no	9.454	9.464	EPSD	TCGA;ICGC;COSMIC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q15746	MYLK	P27361	MAPK3	T1230	M1236I	1236	Missense	distal	6	no	16.362	16.442	EPSD	TCGA	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q15746	MYLK	P27361	MAPK3	T1230	P1237S	1237	Missense	distal	7	no	16.362	16.285	EPSD	TCGA;ICGC;COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q15746	MYLK	P27361	MAPK3	T1230	A1235V	1235	Missense	distal	5	no	16.362	16.351	EPSD	TCGA;ICGC;COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q15746	MYLK	P27361	MAPK3	T1230	M1236L	1236	Missense	distal	6	no	16.362	16.655	EPSD	TCGA;ICGC;COSMIC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q15746	MYLK	P27361	MAPK3	S1659	D1664G	1664	Missense	distal	5	no	14.109	14.086	EPSD	TCGA;ICGC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q15746	MYLK	P27361	MAPK3	S1776	P1780S	1780	Missense	distal	4	no	16.022	16.071	EPSD	TCGA;COSMIC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q15746	MYLK	P27361	MAPK3	S1779	P1780S	1780	Missense	proximal	1	no	17.370	8.316	PhosphoSitePlus	TCGA;COSMIC	9.358	Loss
CMGC_MAPK_ERK1_MAPK3_ST	O75581	LRP6	P27361	MAPK3	S1430	S1431Y	1431	Missense	proximal	1	no	8.360	10.365	EPSD	TCGA;COSMIC	9.358	Gain
CMGC_MAPK_ERK1_MAPK3_ST	O75581	LRP6	P27361	MAPK3	S1430	S1431F	1431	Missense	proximal	1	no	8.360	11.199	EPSD	TCGA;COSMIC	9.358	Gain
CMGC_MAPK_ERK1_MAPK3_ST	O75581	LRP6	P27361	MAPK3	S1508	G1503E	1503	Missense	distal	-5	no	16.432	16.441	EPSD	TCGA;COSMIC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	O75581	LRP6	P27361	MAPK3	S1508	S1505Y	1505	Missense	distal	-3	no	16.432	16.369	EPSD	TCGA	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	O75581	LRP6	P27361	MAPK3	T1511	S1505Y	1505	Missense	distal	-6	no	9.366	9.113	EPSD	TCGA	9.358	Loss
CMGC_MAPK_ERK1_MAPK3_ST	O75581	LRP6	P27361	MAPK3	S1516	R1523W	1523	Missense	distal	7	no	9.043	9.619	EPSD	TCGA;COSMIC	9.358	Gain
CMGC_MAPK_ERK1_MAPK3_ST	O75581	LRP6	P27361	MAPK3	S1521	R1523W	1523	Missense	proximal	2	no	11.130	11.069	EPSD	TCGA;COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	O75581	LRP6	P27361	MAPK3	S1521	H1524Q	1524	Missense	distal	3	no	11.130	11.122	EPSD	TCGA;COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	O75581	LRP6	P27361	MAPK3	S1521	H1524Y	1524	Missense	distal	3	no	11.130	11.114	EPSD	TCGA	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	O75581	LRP6	P27361	MAPK3	S1521	P1519S	1519	Missense	proximal	-2	no	11.130	10.054	EPSD	TCGA;COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	O75581	LRP6	P27361	MAPK3	T1530	R1523W	1523	Missense	distal	-7	no	17.151	17.397	EPSD	TCGA;COSMIC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	O75581	LRP6	P27361	MAPK3	T1530	H1524Q	1524	Missense	distal	-6	no	17.151	17.165	EPSD	TCGA;COSMIC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	O75581	LRP6	P27361	MAPK3	T1530	H1524Y	1524	Missense	distal	-6	no	17.151	17.063	EPSD	TCGA	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	O75581	LRP6	P27361	MAPK3	T1572	S1579P	1579	Missense	distal	7	no	17.564	17.641	EPSD;PhosphoSitePlus	TCGA;COSMIC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	O75581	LRP6	P27361	MAPK3	T1572	R1574Q	1574	Missense	proximal	2	no	17.564	17.554	EPSD;PhosphoSitePlus	TCGA;COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	O75581	LRP6	P27361	MAPK3	S1575	S1579P	1579	Missense	distal	4	no	10.244	10.195	EPSD	TCGA;COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	O75581	LRP6	P27361	MAPK3	S1575	R1574Q	1574	Missense	proximal	-1	no	10.244	10.205	EPSD	TCGA;COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	O75581	LRP6	P27361	MAPK3	S1590	S1596G	1596	Missense	distal	6	no	19.917	19.684	EPSD	TCGA;COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	O75581	LRP6	P27361	MAPK3	S1607	P1604T	1604	Missense	distal	-3	no	21.647	21.609	EPSD	TCGA;COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q02447	SP3	P27361	MAPK3	S73	I69M	69	Missense	distal	-4	no	18.394	18.374	PhosphoSitePlus	TCGA;COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q02447	SP3	P27361	MAPK3	S317	R315W	315	Missense	proximal	-2	no	16.716	14.820	EPSD	TCGA;COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q02447	SP3	P27361	MAPK3	S544	N541D	541	Missense	distal	-3	no	13.899	13.920	EPSD	TCGA;COSMIC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q8IX03	WWC1	P27361	MAPK3	S255	H256Y	256	Missense	proximal	1	no	8.811	9.518	EPSD	TCGA;ICGC;COSMIC	9.358	Gain
CMGC_MAPK_ERK1_MAPK3_ST	Q8IX03	WWC1	P27361	MAPK3	S270	S265C	265	Missense	distal	-5	no	11.158	10.996	EPSD	TCGA;ICGC;COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q8IX03	WWC1	P27361	MAPK3	S270	S269L	269	Missense	proximal	-1	no	11.158	11.069	EPSD	TCGA;ICGC;COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q8IX03	WWC1	P27361	MAPK3	S441	R446Q	446	Missense	distal	5	no	11.099	11.098	EPSD	TCGA;ICGC;COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q8IX03	WWC1	P27361	MAPK3	T527	S525F	525	Missense	proximal	-2	no	16.615	15.315	EPSD	TCGA;ICGC;COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q8IX03	WWC1	P27361	MAPK3	T527	P528S	528	Missense	proximal	1	no	16.615	7.562	EPSD	TCGA;ICGC;COSMIC	9.358	Loss
CMGC_MAPK_ERK1_MAPK3_ST	Q8IX03	WWC1	P27361	MAPK3	T527	S523F	523	Missense	distal	-4	no	16.615	16.426	EPSD	TCGA;ICGC;COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q8IX03	WWC1	P27361	MAPK3	T527	S533F	533	Missense	distal	6	no	16.615	15.901	EPSD	TCGA;ICGC;COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q8IX03	WWC1	P27361	MAPK3	T527	M531I	531	Missense	distal	4	no	16.615	16.652	EPSD	TCGA;ICGC;COSMIC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q8IX03	WWC1	P27361	MAPK3	T532	S533F	533	Missense	proximal	1	no	7.478	10.318	EPSD	TCGA;ICGC;COSMIC	9.358	Gain
CMGC_MAPK_ERK1_MAPK3_ST	Q8IX03	WWC1	P27361	MAPK3	S535	R537C	537	Missense	proximal	2	no	17.324	17.276	EPSD	TCGA;ICGC;COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q8IX03	WWC1	P27361	MAPK3	S535	P528S	528	Missense	distal	-7	no	17.324	17.287	EPSD	TCGA;ICGC;COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q8IX03	WWC1	P27361	MAPK3	S535	L540F	540	Missense	distal	5	no	17.324	17.171	EPSD	TCGA;ICGC;COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q8IX03	WWC1	P27361	MAPK3	S535	P536S	536	Missense	proximal	1	no	17.324	8.271	EPSD	TCGA;ICGC;COSMIC	9.358	Loss
CMGC_MAPK_ERK1_MAPK3_ST	Q8IX03	WWC1	P27361	MAPK3	S535	S533F	533	Missense	proximal	-2	no	17.324	16.024	EPSD	TCGA;ICGC;COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q8IX03	WWC1	P27361	MAPK3	S535	M531I	531	Missense	distal	-4	no	17.324	17.345	EPSD	TCGA;ICGC;COSMIC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q8IX03	WWC1	P27361	MAPK3	S539	L540F	540	Missense	proximal	1	no	8.524	11.348	EPSD	TCGA;ICGC;COSMIC	9.358	Gain
CMGC_MAPK_ERK1_MAPK3_ST	Q8IX03	WWC1	P27361	MAPK3	S542	P549L	549	Missense	distal	7	no	17.035	17.228	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q8IX03	WWC1	P27361	MAPK3	S542	R537C	537	Missense	distal	-5	no	17.035	16.919	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q8IX03	WWC1	P27361	MAPK3	S542	L540F	540	Missense	proximal	-2	no	17.035	16.044	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q8IX03	WWC1	P27361	MAPK3	S542	S548F	548	Missense	distal	6	no	17.035	16.322	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q8IX03	WWC1	P27361	MAPK3	S542	P536S	536	Missense	distal	-6	no	17.035	17.120	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q8IX03	WWC1	P27361	MAPK3	S548	P549L	549	Missense	proximal	1	no	19.648	10.610	PhosphoSitePlus;EPSD	TCGA;ICGC;COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q8IX03	WWC1	P27361	MAPK3	S548	M551I	551	Missense	distal	3	no	19.648	19.658	PhosphoSitePlus;EPSD	TCGA;ICGC;COSMIC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q8IX03	WWC1	P27361	MAPK3	S548	S548F	548	Missense	central	0	yes	19.648	0.000	PhosphoSitePlus;EPSD	TCGA;ICGC;COSMIC	9.358	Loss
CMGC_MAPK_ERK1_MAPK3_ST	Q8IX03	WWC1	P27361	MAPK3	T596	E597Q	597	Missense	proximal	1	no	8.558	9.862	EPSD	TCGA;ICGC;COSMIC	9.358	Gain
CMGC_MAPK_ERK1_MAPK3_ST	Q8IX03	WWC1	P27361	MAPK3	S876	A875D	875	Missense	proximal	-1	no	14.104	14.191	EPSD	TCGA;ICGC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q8IX03	WWC1	P27361	MAPK3	T895	P898S	898	Missense	distal	3	no	16.724	16.719	EPSD	TCGA;ICGC;COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q8IX03	WWC1	P27361	MAPK3	T895	S899P	899	Missense	distal	4	no	16.724	16.675	EPSD	TCGA;ICGC;COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q8IX03	WWC1	P27361	MAPK3	S899	P898S	898	Missense	proximal	-1	no	16.387	16.381	EPSD	TCGA;ICGC;COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q8IX03	WWC1	P27361	MAPK3	S899	S899P	899	Missense	central	0	yes	16.387	0.000	EPSD	TCGA;ICGC;COSMIC	9.358	Loss
CMGC_MAPK_ERK1_MAPK3_ST	Q8IX03	WWC1	P27361	MAPK3	T912	S914F	914	Missense	proximal	2	no	14.243	14.192	EPSD	TCGA;ICGC;COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q8IX03	WWC1	P27361	MAPK3	T912	P913L	913	Missense	proximal	1	no	14.243	5.205	EPSD	TCGA	9.358	Loss
CMGC_MAPK_ERK1_MAPK3_ST	Q8IX03	WWC1	P27361	MAPK3	S914	R920L	920	Missense	distal	6	no	9.490	9.375	EPSD	TCGA;ICGC;COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q8IX03	WWC1	P27361	MAPK3	S914	S914F	914	Missense	central	0	yes	9.490	0.000	EPSD	TCGA;ICGC;COSMIC	9.358	Loss
CMGC_MAPK_ERK1_MAPK3_ST	Q8IX03	WWC1	P27361	MAPK3	S914	P913L	913	Missense	proximal	-1	no	9.490	9.395	EPSD	TCGA	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q8IX03	WWC1	P27361	MAPK3	T929	R926C	926	Missense	distal	-3	no	10.266	10.126	EPSD	TCGA;ICGC;COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q8IX03	WWC1	P27361	MAPK3	T929	S931F	931	Missense	proximal	2	no	10.266	10.215	EPSD	TCGA;ICGC;COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q8IX03	WWC1	P27361	MAPK3	T929	F930S	930	Missense	proximal	1	no	10.266	7.426	EPSD	TCGA;ICGC;COSMIC	9.358	Loss
CMGC_MAPK_ERK1_MAPK3_ST	Q8IX03	WWC1	P27361	MAPK3	S931	R926C	926	Missense	distal	-5	no	16.230	16.114	EPSD	TCGA;ICGC;COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q8IX03	WWC1	P27361	MAPK3	S931	Q937K	937	Missense	distal	6	no	16.230	16.334	EPSD	TCGA;ICGC;COSMIC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q8IX03	WWC1	P27361	MAPK3	S931	S931F	931	Missense	central	0	yes	16.230	0.000	EPSD	TCGA;ICGC;COSMIC	9.358	Loss
CMGC_MAPK_ERK1_MAPK3_ST	Q8IX03	WWC1	P27361	MAPK3	S931	F930S	930	Missense	proximal	-1	no	16.230	16.434	EPSD	TCGA;ICGC;COSMIC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q8IX03	WWC1	P27361	MAPK3	S936	Q937K	937	Missense	proximal	1	no	9.850	0.640	EPSD	TCGA;ICGC;COSMIC	9.358	Loss
CMGC_MAPK_ERK1_MAPK3_ST	Q8IX03	WWC1	P27361	MAPK3	S936	V939L	939	Missense	distal	3	no	9.850	9.855	EPSD	TCGA;ICGC;COSMIC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q8IX03	WWC1	P27361	MAPK3	S936	S931F	931	Missense	distal	-5	no	9.850	9.715	EPSD	TCGA;ICGC;COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q8IX03	WWC1	P27361	MAPK3	S936	R941W	941	Missense	distal	5	no	9.850	9.382	EPSD	TCGA;ICGC;COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q8IX03	WWC1	P27361	MAPK3	S936	F930S	930	Missense	distal	-6	no	9.850	10.317	EPSD	TCGA;ICGC;COSMIC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P11362	FGFR1	P27361	MAPK3	T454	S461F	461	Missense	distal	7	no	14.335	14.826	EPSD	TCGA;COSMIC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P11362	FGFR1	P27361	MAPK3	S588	P587L	587	Missense	proximal	-1	no	9.602	9.508	EPSD	TCGA;COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	O15525	MAFG	P27361	MAPK3	S124	R119Q	119	Missense	distal	-5	no	15.420	15.413	PhosphoSitePlus	TCGA;ICGC;COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P14784	IL2RB	P27361	MAPK3	T282	F288L	288	Missense	distal	6	no	11.124	11.481	EPSD	TCGA;ICGC;COSMIC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P14784	IL2RB	P27361	MAPK3	S431	P438A	438	Missense	distal	7	no	14.421	14.690	EPSD	TCGA;ICGC;COSMIC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P14784	IL2RB	P27361	MAPK3	S431	S433R	433	Missense	proximal	2	no	14.421	14.409	EPSD	TCGA;ICGC;COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P14784	IL2RB	P27361	MAPK3	S458	R454K	454	Missense	distal	-4	no	9.727	9.720	EPSD	TCGA;ICGC;COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P14784	IL2RB	P27361	MAPK3	S458	E452K	452	Missense	distal	-6	no	9.727	9.586	EPSD	TCGA;ICGC;COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P14784	IL2RB	P27361	MAPK3	S458	R462K	462	Missense	distal	4	no	9.727	9.736	EPSD	TCGA;ICGC;COSMIC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P14784	IL2RB	P27361	MAPK3	S458	P457S	457	Missense	proximal	-1	no	9.727	9.722	EPSD	TCGA;ICGC;COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P14784	IL2RB	P27361	MAPK3	T476	P474S	474	Missense	proximal	-2	no	15.038	13.962	PhosphoSitePlus	TCGA;ICGC;COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P14784	IL2RB	P27361	MAPK3	T476	P480S	480	Missense	distal	4	no	15.038	15.087	PhosphoSitePlus	TCGA;ICGC;COSMIC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P14784	IL2RB	P27361	MAPK3	T533	R528C	528	Missense	distal	-5	no	9.774	9.657	EPSD	TCGA;ICGC;COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P06239	LCK	P27361	MAPK3	S59	E52K	52	Missense	distal	-7	no	17.222	17.273	PhosphoSitePlus	TCGA;ICGC;COSMIC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P06239	LCK	P27361	MAPK3	S59	P56L	56	Missense	distal	-3	no	17.222	17.137	PhosphoSitePlus	TCGA;ICGC;COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P06239	LCK	P27361	MAPK3	S75	D77V	77	Missense	proximal	2	no	9.553	9.539	EPSD	TCGA;COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P06239	LCK	P27361	MAPK3	S75	L80M	80	Missense	distal	5	no	9.553	9.433	EPSD	TCGA	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P06239	LCK	P27361	MAPK3	S75	A68V	68	Missense	distal	-7	no	9.553	9.552	EPSD	TCGA	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P06239	LCK	P27361	MAPK3	S156	E157K	157	Missense	proximal	1	no	10.064	2.159	EPSD	TCGA;COSMIC	9.358	Loss
CMGC_MAPK_ERK1_MAPK3_ST	P06239	LCK	P27361	MAPK3	S162	E157K	157	Missense	distal	-5	no	9.683	9.672	EPSD	TCGA;COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P06239	LCK	P27361	MAPK3	S194	F191L	191	Missense	distal	-3	no	16.825	16.891	EPSD	TCGA;COSMIC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P06239	LCK	P27361	MAPK3	S194	P200S	200	Missense	distal	6	no	16.825	16.955	EPSD	TCGA;COSMIC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P06239	LCK	P27361	MAPK3	S194	R196Q	196	Missense	proximal	2	no	16.825	16.816	EPSD	TCGA;COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P06239	LCK	P27361	MAPK3	S281	Q277K	277	Missense	distal	-4	no	15.533	15.516	EPSD	TCGA;COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P06239	LCK	P27361	MAPK3	S281	S274N	274	Missense	distal	-7	no	15.533	15.601	EPSD	TCGA;COSMIC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P06239	LCK	P27361	MAPK3	S281	S281F	281	Missense	central	0	yes	15.533	0.000	EPSD	TCGA;COSMIC	9.358	Loss
CMGC_MAPK_ERK1_MAPK3_ST	P06239	LCK	P27361	MAPK3	S281	A284T	284	Missense	distal	3	no	15.533	15.564	EPSD	TCGA	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P06239	LCK	P27361	MAPK3	S373	V372M	372	Missense	proximal	-1	no	9.982	9.910	EPSD	TCGA;COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P06239	LCK	P27361	MAPK3	S373	T375I	375	Missense	proximal	2	no	9.982	9.958	EPSD	TCGA	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P06239	LCK	P27361	MAPK3	S373	R366Q	366	Missense	distal	-7	no	9.982	9.981	EPSD	TCGA;COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P06239	LCK	P27361	MAPK3	T501	Y505C	505	Missense	distal	4	no	11.178	10.891	EPSD	TCGA;ICGC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P42702	LIFR	P27361	MAPK3	S368	R365H	365	Missense	distal	-3	no	10.615	10.621	EPSD	TCGA;ICGC;COSMIC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P42702	LIFR	P27361	MAPK3	S368	R365C	365	Missense	distal	-3	no	10.615	10.475	EPSD	TCGA;ICGC;COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P42702	LIFR	P27361	MAPK3	S368	S368N	368	Missense	central	0	yes	10.615	0.000	EPSD	TCGA;ICGC;COSMIC	9.358	Loss
CMGC_MAPK_ERK1_MAPK3_ST	P42702	LIFR	P27361	MAPK3	S534	A533D	533	Missense	proximal	-1	no	17.155	17.242	EPSD	TCGA;ICGC;COSMIC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P42702	LIFR	P27361	MAPK3	S534	E532K	532	Missense	proximal	-2	no	17.155	16.461	EPSD	TCGA;ICGC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P42702	LIFR	P27361	MAPK3	T541	S546R	546	Missense	distal	5	no	10.356	10.213	EPSD	TCGA;ICGC;COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P42702	LIFR	P27361	MAPK3	T541	W542C	542	Missense	proximal	1	no	10.356	2.952	EPSD	TCGA;ICGC	9.358	Loss
CMGC_MAPK_ERK1_MAPK3_ST	P42702	LIFR	P27361	MAPK3	T904	L911V	911	Missense	distal	7	no	15.727	15.775	EPSD	TCGA;ICGC;COSMIC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P42702	LIFR	P27361	MAPK3	T904	P902S	902	Missense	proximal	-2	no	15.727	14.651	EPSD	TCGA;ICGC;COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P42702	LIFR	P27361	MAPK3	T904	P902H	902	Missense	proximal	-2	no	15.727	14.499	EPSD	TCGA;ICGC;COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P42702	LIFR	P27361	MAPK3	S927	R932H	932	Missense	distal	5	no	16.348	16.384	EPSD	TCGA;ICGC;COSMIC;GDSC;CCLE	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P42702	LIFR	P27361	MAPK3	S1041	N1038T	1038	Missense	distal	-3	no	17.599	17.613	EPSD	TCGA;ICGC;COSMIC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P42702	LIFR	P27361	MAPK3	S1041	D1043N	1043	Missense	proximal	2	no	17.599	17.593	EPSD	TCGA;ICGC;COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P42702	LIFR	P27361	MAPK3	S1041	S1047F	1047	Missense	distal	6	no	17.599	16.886	EPSD	TCGA;ICGC;COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P42702	LIFR	P27361	MAPK3	S1041	P1045L	1045	Missense	distal	4	no	17.599	17.445	EPSD	TCGA;ICGC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P42702	LIFR	P27361	MAPK3	S1044	N1038T	1038	Missense	distal	-6	no	17.176	17.130	PhosphoSitePlus	TCGA;ICGC;COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P42702	LIFR	P27361	MAPK3	S1044	D1043N	1043	Missense	proximal	-1	no	17.176	17.174	PhosphoSitePlus	TCGA;ICGC;COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P42702	LIFR	P27361	MAPK3	S1044	N1051Y	1051	Missense	distal	7	no	17.176	17.265	PhosphoSitePlus	TCGA;ICGC;COSMIC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P42702	LIFR	P27361	MAPK3	S1044	S1047F	1047	Missense	distal	3	no	17.176	17.112	PhosphoSitePlus	TCGA;ICGC;COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P42702	LIFR	P27361	MAPK3	S1044	P1045L	1045	Missense	proximal	1	no	17.176	8.138	PhosphoSitePlus	TCGA;ICGC	9.358	Loss
CMGC_MAPK_ERK1_MAPK3_ST	P42702	LIFR	P27361	MAPK3	S1056	S1062F	1062	Missense	distal	6	no	11.583	10.870	EPSD	TCGA;ICGC;COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P42702	LIFR	P27361	MAPK3	S1056	N1051Y	1051	Missense	distal	-5	no	11.583	11.560	EPSD	TCGA;ICGC;COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P42702	LIFR	P27361	MAPK3	S1056	G1058E	1058	Missense	proximal	2	no	11.583	11.591	EPSD	TCGA;ICGC;COSMIC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P42702	LIFR	P27361	MAPK3	S1056	I1054L	1054	Missense	proximal	-2	no	11.583	12.037	EPSD	TCGA;ICGC;COSMIC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P42702	LIFR	P27361	MAPK3	S1059	S1062F	1062	Missense	distal	3	no	16.075	16.010	EPSD	TCGA;ICGC;COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P42702	LIFR	P27361	MAPK3	S1059	R1066Q	1066	Missense	distal	7	no	16.075	16.105	EPSD	TCGA;ICGC;COSMIC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P42702	LIFR	P27361	MAPK3	S1059	G1058E	1058	Missense	proximal	-1	no	16.075	16.116	EPSD	TCGA;ICGC;COSMIC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P42702	LIFR	P27361	MAPK3	S1059	S1065F	1065	Missense	distal	6	no	16.075	15.361	EPSD	TCGA;ICGC;COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P42702	LIFR	P27361	MAPK3	S1059	I1054L	1054	Missense	distal	-5	no	16.075	16.110	EPSD	TCGA;ICGC;COSMIC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P42702	LIFR	P27361	MAPK3	S1062	S1062F	1062	Missense	central	0	yes	11.245	0.000	EPSD	TCGA;ICGC;COSMIC	9.358	Loss
CMGC_MAPK_ERK1_MAPK3_ST	P42702	LIFR	P27361	MAPK3	S1062	R1066Q	1066	Missense	distal	4	no	11.245	11.201	EPSD	TCGA;ICGC;COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P42702	LIFR	P27361	MAPK3	S1062	G1058E	1058	Missense	distal	-4	no	11.245	11.259	EPSD	TCGA;ICGC;COSMIC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P42702	LIFR	P27361	MAPK3	S1062	S1065F	1065	Missense	distal	3	no	11.245	11.181	EPSD	TCGA;ICGC;COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P42702	LIFR	P27361	MAPK3	S1065	R1066Q	1066	Missense	proximal	1	no	8.322	9.879	EPSD	TCGA;ICGC;COSMIC	9.358	Gain
CMGC_MAPK_ERK1_MAPK3_ST	P42702	LIFR	P27361	MAPK3	S1077	G1082E	1082	Missense	distal	5	no	17.669	17.710	EPSD	TCGA;ICGC;COSMIC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P42702	LIFR	P27361	MAPK3	S1077	G1083E	1083	Missense	distal	6	no	17.669	17.770	EPSD	TCGA;ICGC;COSMIC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P42702	LIFR	P27361	MAPK3	S1086	T1088K	1088	Missense	proximal	2	no	12.169	12.164	EPSD	TCGA;ICGC;COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P42702	LIFR	P27361	MAPK3	S1086	G1082E	1082	Missense	distal	-4	no	12.169	12.184	EPSD	TCGA;ICGC;COSMIC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P42702	LIFR	P27361	MAPK3	S1086	G1083E	1083	Missense	distal	-3	no	12.169	12.182	EPSD	TCGA;ICGC;COSMIC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q14247	CTTN	P27361	MAPK3	S113	Q114P	114	Missense	proximal	1	no	8.661	16.605	EPSD	TCGA;ICGC;COSMIC	9.358	Gain
CMGC_MAPK_ERK1_MAPK3_ST	Q08499	PDE4D	P27361	MAPK3	S18	G23E	23	Missense	distal	5	no	10.692	10.733	EPSD	TCGA;ICGC;COSMIC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q08499	PDE4D	P27361	MAPK3	S164	M169T	169	Missense	distal	5	no	13.348	13.603	EPSD	TCGA;ICGC;COSMIC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q08499	PDE4D	P27361	MAPK3	S164	G158S	158	Missense	distal	-6	no	13.348	13.410	EPSD	TCGA;ICGC;COSMIC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q08499	PDE4D	P27361	MAPK3	S164	P165S	165	Missense	proximal	1	no	13.348	4.294	EPSD	TCGA;ICGC;COSMIC	9.358	Loss
CMGC_MAPK_ERK1_MAPK3_ST	Q08499	PDE4D	P27361	MAPK3	S164	A161V	161	Missense	distal	-3	no	13.348	13.367	EPSD	TCGA;ICGC;COSMIC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q08499	PDE4D	P27361	MAPK3	S164	R163W	163	Missense	proximal	-1	no	13.348	13.109	EPSD	TCGA;ICGC;COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q08499	PDE4D	P27361	MAPK3	S164	R163Q	163	Missense	proximal	-1	no	13.348	13.309	EPSD	TCGA;ICGC;COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q08499	PDE4D	P27361	MAPK3	S171	M169T	169	Missense	proximal	-2	no	15.078	16.846	EPSD	TCGA;ICGC;COSMIC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q08499	PDE4D	P27361	MAPK3	S171	P165S	165	Missense	distal	-6	no	15.078	15.162	EPSD	TCGA;ICGC;COSMIC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q08499	PDE4D	P27361	MAPK3	S171	S174F	174	Missense	distal	3	no	15.078	15.013	EPSD	TCGA;ICGC;COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q08499	PDE4D	P27361	MAPK3	S202	S195T	195	Missense	distal	-7	no	16.308	16.385	EPSD	TCGA;ICGC;COSMIC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q08499	PDE4D	P27361	MAPK3	S202	S207P	207	Missense	distal	5	no	16.308	16.265	EPSD	TCGA	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q08499	PDE4D	P27361	MAPK3	S202	D196N	196	Missense	distal	-6	no	16.308	16.247	EPSD	TCGA;ICGC;COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q08499	PDE4D	P27361	MAPK3	T224	G218R	218	Missense	distal	-6	no	13.622	13.524	EPSD	TCGA;ICGC;COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q08499	PDE4D	P27361	MAPK3	T224	G218E	218	Missense	distal	-6	no	13.622	13.668	EPSD	TCGA;ICGC;COSMIC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q08499	PDE4D	P27361	MAPK3	S255	N259K	259	Missense	distal	4	no	15.109	15.117	EPSD	TCGA;ICGC;COSMIC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q08499	PDE4D	P27361	MAPK3	S255	S262T	262	Missense	distal	7	no	15.109	15.227	EPSD	TCGA	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q08499	PDE4D	P27361	MAPK3	T336	E331Q	331	Missense	distal	-5	no	11.009	10.991	EPSD	TCGA;ICGC;COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q08499	PDE4D	P27361	MAPK3	T336	E331A	331	Missense	distal	-5	no	11.009	10.945	EPSD	TCGA;ICGC;COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q08499	PDE4D	P27361	MAPK3	T336	F337L	337	Missense	proximal	1	no	11.009	8.185	EPSD	TCGA;ICGC;COSMIC	9.358	Loss
CMGC_MAPK_ERK1_MAPK3_ST	Q08499	PDE4D	P27361	MAPK3	S348	T350S	350	Missense	proximal	2	no	16.099	16.111	EPSD	TCGA;ICGC;COSMIC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q08499	PDE4D	P27361	MAPK3	S348	K354N	354	Missense	distal	6	no	16.099	16.078	EPSD	TCGA;ICGC;COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q08499	PDE4D	P27361	MAPK3	S374	L370F	370	Missense	distal	-4	no	9.804	9.756	EPSD	TCGA;ICGC;COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q08499	PDE4D	P27361	MAPK3	S657	D661N	661	Missense	distal	4	no	15.411	15.384	EPSD	TCGA;ICGC;COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q08499	PDE4D	P27361	MAPK3	S657	C660F	660	Missense	distal	3	no	15.411	15.432	EPSD	TCGA;ICGC;COSMIC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q08499	PDE4D	P27361	MAPK3	S806	R805H	805	Missense	proximal	-1	no	18.466	18.469	EPSD	TCGA;ICGC;COSMIC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q08499	PDE4D	P27361	MAPK3	S806	R805C	805	Missense	proximal	-1	no	18.466	18.281	EPSD	TCGA;ICGC;COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q08499	PDE4D	P27361	MAPK3	S806	V801G	801	Missense	distal	-5	no	18.466	18.499	EPSD	TCGA;ICGC;COSMIC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P04637	TP53	P27361	MAPK3	S20	P27S	27	Missense	distal	7	no	10.750	10.673	EPSD	TCGA;ICGC;COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P04637	TP53	P27361	MAPK3	S20	P27L	27	Missense	distal	7	no	10.750	10.943	EPSD	TCGA;ICGC;COSMIC;GDSC;CCLE	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P04637	TP53	P27361	MAPK3	S33	P27S	27	Missense	distal	-6	no	15.325	15.410	EPSD	TCGA;ICGC;COSMIC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P04637	TP53	P27361	MAPK3	S33	P27L	27	Missense	distal	-6	no	15.325	15.078	EPSD	TCGA;ICGC;COSMIC;GDSC;CCLE	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P04637	TP53	P27361	MAPK3	S46	D48N	48	Missense	proximal	2	no	14.562	14.556	EPSD	TCGA;ICGC;COSMIC;GDSC;CCLE	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P04637	TP53	P27361	MAPK3	T81	A79V	79	Missense	proximal	-2	no	16.918	17.615	EPSD	TCGA;ICGC;COSMIC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P04637	TP53	P27361	MAPK3	T81	P77L	77	Missense	distal	-4	no	16.918	16.806	EPSD	TCGA;ICGC;COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P04637	TP53	P27361	MAPK3	T81	P82L	82	Missense	proximal	1	no	16.918	7.880	EPSD	TCGA;ICGC;COSMIC	9.358	Loss
CMGC_MAPK_ERK1_MAPK3_ST	P04637	TP53	P27361	MAPK3	T81	A74T	74	Missense	distal	-7	no	16.918	16.845	EPSD	TCGA;ICGC;COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P04637	TP53	P27361	MAPK3	S127	K132N	132	Missense	distal	5	no	16.318	16.347	EPSD	TCGA;ICGC;COSMIC;GDSC;CCLE	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P04637	TP53	P27361	MAPK3	S127	S121Y	121	Missense	distal	-6	no	16.318	16.064	EPSD	TCGA;ICGC;COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P04637	TP53	P27361	MAPK3	S127	M133K	133	Missense	distal	6	no	16.318	16.759	EPSD	TCGA;ICGC;COSMIC;CCLE	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P04637	TP53	P27361	MAPK3	S127	K132E	132	Missense	distal	5	no	16.318	16.446	EPSD	TCGA;ICGC;COSMIC;GDSC;CCLE	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P04637	TP53	P27361	MAPK3	S127	Y126C	126	Missense	proximal	-1	no	16.318	16.168	EPSD	TCGA;ICGC;COSMIC;GDSC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P04637	TP53	P27361	MAPK3	S127	S127P	127	Missense	central	0	yes	16.318	0.000	EPSD	TCGA;ICGC;COSMIC;GDSC;CCLE	9.358	Loss
CMGC_MAPK_ERK1_MAPK3_ST	P04637	TP53	P27361	MAPK3	S127	Y126N	126	Missense	proximal	-1	no	16.318	16.346	EPSD	TCGA;ICGC;COSMIC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P04637	TP53	P27361	MAPK3	S127	L130V	130	Missense	distal	3	no	16.318	16.312	EPSD	TCGA;ICGC;COSMIC;GDSC;CCLE	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P04637	TP53	P27361	MAPK3	S127	K132T	132	Missense	distal	5	no	16.318	16.334	EPSD	TCGA;ICGC;COSMIC;GDSC;CCLE	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P04637	TP53	P27361	MAPK3	S127	S127Y	127	Missense	central	0	yes	16.318	0.000	EPSD	TCGA;ICGC;COSMIC	9.358	Loss
CMGC_MAPK_ERK1_MAPK3_ST	P04637	TP53	P27361	MAPK3	S127	S127F	127	Missense	central	0	yes	16.318	0.000	EPSD	TCGA;ICGC;COSMIC;CCLE	9.358	Loss
CMGC_MAPK_ERK1_MAPK3_ST	P04637	TP53	P27361	MAPK3	S127	M133R	133	Missense	distal	6	no	16.318	16.725	EPSD	TCGA;ICGC;COSMIC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P04637	TP53	P27361	MAPK3	S127	K132R	132	Missense	distal	5	no	16.318	16.326	EPSD	TCGA;ICGC;COSMIC;GDSC;CCLE	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P04637	TP53	P27361	MAPK3	S127	F134L	134	Missense	distal	7	no	16.318	16.097	EPSD	TCGA;ICGC;COSMIC;CCLE	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P04637	TP53	P27361	MAPK3	S127	Y126S	126	Missense	proximal	-1	no	16.318	16.394	EPSD	TCGA;ICGC;COSMIC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P04637	TP53	P27361	MAPK3	S127	L130P	130	Missense	distal	3	no	16.318	16.354	EPSD	TCGA;ICGC;COSMIC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P04637	TP53	P27361	MAPK3	S127	L130F	130	Missense	distal	3	no	16.318	16.285	EPSD	TCGA;ICGC;COSMIC;CCLE	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P04637	TP53	P27361	MAPK3	S127	F134V	134	Missense	distal	7	no	16.318	16.145	EPSD	TCGA;ICGC;COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P04637	TP53	P27361	MAPK3	S127	T125M	125	Missense	proximal	-2	no	16.318	14.549	EPSD	TCGA;ICGC;COSMIC;GDSC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P04637	TP53	P27361	MAPK3	S127	Y126D	126	Missense	proximal	-1	no	16.318	16.348	EPSD	TCGA;ICGC;COSMIC;GDSC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P04637	TP53	P27361	MAPK3	S127	K120E	120	Missense	distal	-7	no	16.318	16.266	EPSD	TCGA;ICGC;COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P04637	TP53	P27361	MAPK3	S127	N131S	131	Missense	distal	4	no	16.318	16.464	EPSD	TCGA;ICGC;COSMIC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P04637	TP53	P27361	MAPK3	S127	T125P	125	Missense	proximal	-2	no	16.318	17.304	EPSD	TCGA;ICGC;COSMIC;CCLE	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P04637	TP53	P27361	MAPK3	S127	S127C	127	Missense	central	0	yes	16.318	0.000	EPSD	TCGA;ICGC;COSMIC;CCLE	9.358	Loss
CMGC_MAPK_ERK1_MAPK3_ST	P04637	TP53	P27361	MAPK3	S127	N131I	131	Missense	distal	4	no	16.318	16.123	EPSD	TCGA;ICGC;COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P04637	TP53	P27361	MAPK3	S127	Y126H	126	Missense	proximal	-1	no	16.318	16.355	EPSD	TCGA;ICGC;COSMIC;GDSC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P04637	TP53	P27361	MAPK3	S127	K132Q	132	Missense	distal	5	no	16.318	16.324	EPSD	TCGA;ICGC;COSMIC;GDSC;CCLE	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P04637	TP53	P27361	MAPK3	S127	L130R	130	Missense	distal	3	no	16.318	16.328	EPSD	TCGA;ICGC;COSMIC;CCLE	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P04637	TP53	P27361	MAPK3	T150	W146S	146	Missense	distal	-4	no	12.555	12.840	EPSD	TCGA;ICGC;COSMIC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P04637	TP53	P27361	MAPK3	T150	P152L	152	Missense	proximal	2	no	12.555	12.534	EPSD	TCGA;ICGC;COSMIC;GDSC;CCLE	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P04637	TP53	P27361	MAPK3	T150	D148N	148	Missense	proximal	-2	no	12.555	12.142	EPSD	TCGA;ICGC;COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P04637	TP53	P27361	MAPK3	T150	P151H	151	Missense	proximal	1	no	12.555	4.799	EPSD	TCGA;ICGC;COSMIC;GDSC;CCLE	9.358	Loss
CMGC_MAPK_ERK1_MAPK3_ST	P04637	TP53	P27361	MAPK3	T150	P151A	151	Missense	proximal	1	no	12.555	3.316	EPSD	TCGA;ICGC;COSMIC;CCLE	9.358	Loss
CMGC_MAPK_ERK1_MAPK3_ST	P04637	TP53	P27361	MAPK3	T150	R156P	156	Missense	distal	6	no	12.555	12.667	EPSD	TCGA;ICGC;COSMIC;GDSC;CCLE	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P04637	TP53	P27361	MAPK3	T150	V143A	143	Missense	distal	-7	no	12.555	12.556	EPSD	TCGA;ICGC;COSMIC;GDSC;CCLE	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P04637	TP53	P27361	MAPK3	T150	P151S	151	Missense	proximal	1	no	12.555	3.502	EPSD	TCGA;ICGC;COSMIC;GDSC;CCLE	9.358	Loss
CMGC_MAPK_ERK1_MAPK3_ST	P04637	TP53	P27361	MAPK3	T150	V157F	157	Missense	distal	7	no	12.555	12.728	EPSD	TCGA;ICGC;COSMIC;GDSC;CCLE	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P04637	TP53	P27361	MAPK3	T150	V157G	157	Missense	distal	7	no	12.555	12.377	EPSD	TCGA;ICGC;COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P04637	TP53	P27361	MAPK3	T150	V157D	157	Missense	distal	7	no	12.555	12.344	EPSD	TCGA;ICGC;COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P04637	TP53	P27361	MAPK3	T150	L145R	145	Missense	distal	-5	no	12.555	12.569	EPSD	TCGA;ICGC;COSMIC;GDSC;CCLE	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P04637	TP53	P27361	MAPK3	T150	T155I	155	Missense	distal	5	no	12.555	12.298	EPSD	TCGA;ICGC;COSMIC;CCLE	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P04637	TP53	P27361	MAPK3	T150	V143M	143	Missense	distal	-7	no	12.555	12.611	EPSD	TCGA;ICGC;COSMIC;GDSC;CCLE	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P04637	TP53	P27361	MAPK3	T150	T155N	155	Missense	distal	5	no	12.555	12.569	EPSD	TCGA;ICGC;COSMIC;GDSC;CCLE	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P04637	TP53	P27361	MAPK3	T150	P152S	152	Missense	proximal	2	no	12.555	12.557	EPSD	TCGA;ICGC;COSMIC;CCLE	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P04637	TP53	P27361	MAPK3	T150	R156C	156	Missense	distal	6	no	12.555	11.930	EPSD	TCGA;ICGC;COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P04637	TP53	P27361	MAPK3	T150	P151T	151	Missense	proximal	1	no	12.555	3.678	EPSD	TCGA;ICGC;COSMIC	9.358	Loss
CMGC_MAPK_ERK1_MAPK3_ST	P04637	TP53	P27361	MAPK3	T150	T155P	155	Missense	distal	5	no	12.555	12.648	EPSD	TCGA;ICGC;COSMIC;CCLE	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P04637	TP53	P27361	MAPK3	T150	V143G	143	Missense	distal	-7	no	12.555	12.444	EPSD	TCGA;ICGC;COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P04637	TP53	P27361	MAPK3	T150	P152Q	152	Missense	proximal	2	no	12.555	12.535	EPSD	TCGA;ICGC;COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P04637	TP53	P27361	MAPK3	T150	R156H	156	Missense	distal	6	no	12.555	12.574	EPSD	TCGA;ICGC;COSMIC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P04637	TP53	P27361	MAPK3	T150	L145P	145	Missense	distal	-5	no	12.555	12.610	EPSD	TCGA;ICGC;COSMIC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P04637	TP53	P27361	MAPK3	T150	Q144L	144	Missense	distal	-6	no	12.555	12.374	EPSD	TCGA;ICGC;COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P04637	TP53	P27361	MAPK3	T150	Q144H	144	Missense	distal	-6	no	12.555	12.541	EPSD	TCGA;ICGC;COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P04637	TP53	P27361	MAPK3	T150	G154V	154	Missense	distal	4	no	12.555	12.493	EPSD	TCGA;ICGC;COSMIC;GDSC;CCLE	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P04637	TP53	P27361	MAPK3	T150	V157L	157	Missense	distal	7	no	12.555	12.507	EPSD	TCGA;ICGC;COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P04637	TP53	P27361	MAPK3	T150	P151R	151	Missense	proximal	1	no	12.555	3.055	EPSD	TCGA;ICGC;COSMIC	9.358	Loss
CMGC_MAPK_ERK1_MAPK3_ST	P04637	TP53	P27361	MAPK3	T150	Q144P	144	Missense	distal	-6	no	12.555	12.621	EPSD	TCGA;ICGC;COSMIC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P04637	TP53	P27361	MAPK3	T150	V143E	143	Missense	distal	-7	no	12.555	12.438	EPSD	TCGA;ICGC;COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P04637	TP53	P27361	MAPK3	T150	R156G	156	Missense	distal	6	no	12.555	12.565	EPSD	TCGA;ICGC;COSMIC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P04637	TP53	P27361	MAPK3	T150	P151L	151	Missense	proximal	1	no	12.555	3.517	EPSD	TCGA;ICGC;COSMIC	9.358	Loss
CMGC_MAPK_ERK1_MAPK3_ST	P04637	TP53	P27361	MAPK3	T155	R156P	156	Missense	proximal	1	no	3.205	12.706	EPSD	TCGA;ICGC;COSMIC;GDSC;CCLE	9.358	Gain
CMGC_MAPK_ERK1_MAPK3_ST	P04637	TP53	P27361	MAPK3	S269	C275S	275	Missense	distal	6	no	8.661	9.528	EPSD	TCGA;ICGC;COSMIC	9.358	Gain
CMGC_MAPK_ERK1_MAPK3_ST	P04637	TP53	P27361	MAPK3	S269	R267P	267	Missense	proximal	-2	no	8.661	10.061	EPSD	TCGA;ICGC;COSMIC;GDSC;CCLE	9.358	Gain
CMGC_MAPK_ERK1_MAPK3_ST	P04637	TP53	P27361	MAPK3	S315	K319N	319	Missense	distal	4	no	16.542	16.534	EPSD	TCGA;ICGC;COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P04637	TP53	P27361	MAPK3	S315	K320E	320	Missense	distal	5	no	16.542	16.670	EPSD	TCGA;ICGC;COSMIC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P04637	TP53	P27361	MAPK3	S315	S315C	315	Missense	central	0	yes	16.542	0.000	EPSD	TCGA;ICGC;COSMIC	9.358	Loss
CMGC_MAPK_ERK1_MAPK3_ST	P04637	TP53	P27361	MAPK3	S376	S376C	376	Missense	central	0	yes	10.149	0.000	EPSD	TCGA;ICGC;COSMIC	9.358	Loss
CMGC_MAPK_ERK1_MAPK3_ST	P04637	TP53	P27361	MAPK3	S376	Q375K	375	Missense	proximal	-1	no	10.149	10.174	EPSD	TCGA;ICGC;COSMIC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P04637	TP53	P27361	MAPK3	S378	S376C	376	Missense	proximal	-2	no	9.499	7.059	EPSD	TCGA;ICGC;COSMIC	9.358	Loss
CMGC_MAPK_ERK1_MAPK3_ST	P04637	TP53	P27361	MAPK3	S378	Q375K	375	Missense	distal	-3	no	9.499	9.494	EPSD	TCGA;ICGC;COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P27708	CAD	P27361	MAPK3	T166	R168Q	168	Missense	proximal	2	no	13.797	13.788	EPSD	TCGA;ICGC;COSMIC;CCLE	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P27708	CAD	P27361	MAPK3	T456	Y451C	451	Missense	distal	-5	no	16.501	16.403	PhosphoSitePlus	TCGA;ICGC;COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P27708	CAD	P27361	MAPK3	T456	L453V	453	Missense	distal	-3	no	16.501	16.505	PhosphoSitePlus	TCGA;ICGC;COSMIC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P27708	CAD	P27361	MAPK3	T456	Q462H	462	Missense	distal	6	no	16.501	16.590	PhosphoSitePlus	TCGA;ICGC;COSMIC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P27708	CAD	P27361	MAPK3	T456	P454S	454	Missense	proximal	-2	no	16.501	15.425	PhosphoSitePlus	TCGA;ICGC;COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P27708	CAD	P27361	MAPK3	T504	T508I	508	Missense	distal	4	no	14.150	13.922	EPSD	TCGA;ICGC;COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P27708	CAD	P27361	MAPK3	S586	L589P	589	Missense	distal	3	no	10.028	10.065	EPSD	TCGA;ICGC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P27708	CAD	P27361	MAPK3	S1038	R1033Q	1033	Missense	distal	-5	no	15.210	15.202	EPSD	TCGA;COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P27708	CAD	P27361	MAPK3	S1222	V1226I	1226	Missense	distal	4	no	10.154	10.036	EPSD	TCGA;COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P27708	CAD	P27361	MAPK3	S1222	V1217I	1217	Missense	distal	-5	no	10.154	10.135	EPSD	TCGA	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P27708	CAD	P27361	MAPK3	S1222	F1223Y	1223	Missense	proximal	1	no	10.154	9.319	EPSD	TCGA	9.358	Loss
CMGC_MAPK_ERK1_MAPK3_ST	P27708	CAD	P27361	MAPK3	S1321	N1324D	1324	Missense	distal	3	no	9.505	9.515	EPSD	TCGA;COSMIC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P27708	CAD	P27361	MAPK3	S1407	G1401A	1401	Missense	distal	-6	no	10.659	10.405	EPSD	TCGA;COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P27708	CAD	P27361	MAPK3	S1407	Y1413H	1413	Missense	distal	6	no	10.659	10.818	EPSD	TCGA;COSMIC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P27708	CAD	P27361	MAPK3	S1407	L1405F	1405	Missense	proximal	-2	no	10.659	9.667	EPSD	TCGA;COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P27708	CAD	P27361	MAPK3	S1407	G1401V	1401	Missense	distal	-6	no	10.659	10.392	EPSD	TCGA;COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P27708	CAD	P27361	MAPK3	T1833	R1838H	1838	Missense	distal	5	no	15.527	15.563	EPSD	TCGA;COSMIC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P27708	CAD	P27361	MAPK3	T1833	R1838L	1838	Missense	distal	5	no	15.527	15.400	EPSD	TCGA;COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P27708	CAD	P27361	MAPK3	T1833	E1835Q	1835	Missense	proximal	2	no	15.527	15.514	EPSD	TCGA;COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P27708	CAD	P27361	MAPK3	T1833	P1837H	1837	Missense	distal	4	no	15.527	15.436	EPSD	TCGA	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P27708	CAD	P27361	MAPK3	T1833	G1840D	1840	Missense	distal	7	no	15.527	15.494	EPSD	TCGA;COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P27708	CAD	P27361	MAPK3	T1833	E1829D	1829	Missense	distal	-4	no	15.527	15.516	EPSD	TCGA;COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P27708	CAD	P27361	MAPK3	T1884	G1887C	1887	Missense	distal	3	no	13.281	13.211	EPSD	TCGA;COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P27708	CAD	P27361	MAPK3	T1884	L1881P	1881	Missense	distal	-3	no	13.281	13.365	EPSD	TCGA;COSMIC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P27708	CAD	P27361	MAPK3	T1884	G1883R	1883	Missense	proximal	-1	no	13.281	13.305	EPSD	TCGA;COSMIC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P27708	CAD	P27361	MAPK3	S1900	P1901H	1901	Missense	proximal	1	no	15.232	7.476	EPSD	TCGA;COSMIC	9.358	Loss
CMGC_MAPK_ERK1_MAPK3_ST	P27708	CAD	P27361	MAPK3	S1900	A1899T	1899	Missense	proximal	-1	no	15.232	15.335	EPSD	TCGA;COSMIC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P27708	CAD	P27361	MAPK3	T1906	P1901H	1901	Missense	distal	-5	no	16.229	16.198	EPSD	TCGA;COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P27708	CAD	P27361	MAPK3	T1906	A1899T	1899	Missense	distal	-7	no	16.229	16.156	EPSD	TCGA;COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P27708	CAD	P27361	MAPK3	S1928	V1929F	1929	Missense	proximal	1	no	6.963	10.172	EPSD	TCGA;COSMIC	9.358	Gain
CMGC_MAPK_ERK1_MAPK3_ST	Q969H0	FBXW7	P27361	MAPK3	S26	M33I	33	Missense	distal	7	no	12.241	12.189	EPSD	TCGA;ICGC;COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q969H0	FBXW7	P27361	MAPK3	S372	G368E	368	Missense	distal	-4	no	15.767	15.781	EPSD	TCGA;ICGC;COSMIC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q969H0	FBXW7	P27361	MAPK3	S372	K374Q	374	Missense	proximal	2	no	15.767	15.761	EPSD	TCGA	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q969H0	FBXW7	P27361	MAPK3	S372	W365S	365	Missense	distal	-7	no	15.767	15.438	EPSD	TCGA;ICGC;COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q969H0	FBXW7	P27361	MAPK3	S372	P373S	373	Missense	proximal	1	no	15.767	6.713	EPSD	TCGA;ICGC;COSMIC	9.358	Loss
CMGC_MAPK_ERK1_MAPK3_ST	Q969H0	FBXW7	P27361	MAPK3	S688	R689W	689	Missense	proximal	1	no	9.905	11.502	EPSD	TCGA;ICGC;COSMIC;GDSC;CCLE	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q969H0	FBXW7	P27361	MAPK3	S688	R689Q	689	Missense	proximal	1	no	9.905	11.462	EPSD	TCGA;ICGC;COSMIC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P10275	AR	P27361	MAPK3	T18	R13G	13	Missense	distal	-5	no	10.192	10.194	EPSD	TCGA;ICGC;COSMIC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P10275	AR	P27361	MAPK3	T18	P15L	15	Missense	distal	-3	no	10.192	10.108	EPSD	TCGA;ICGC;COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P10275	AR	P27361	MAPK3	T18	Y19C	19	Missense	proximal	1	no	10.192	1.932	EPSD	TCGA;ICGC	9.358	Loss
CMGC_MAPK_ERK1_MAPK3_ST	P10275	AR	P27361	MAPK3	T18	K17N	17	Missense	proximal	-1	no	10.192	10.198	EPSD	TCGA;ICGC;COSMIC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P10275	AR	P27361	MAPK3	S96	G95S	95	Missense	proximal	-1	no	16.503	16.569	EPSD	TCGA;ICGC;COSMIC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P10275	AR	P27361	MAPK3	S96	E93D	93	Missense	distal	-3	no	16.503	16.500	EPSD	TCGA;ICGC;COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P10275	AR	P27361	MAPK3	S258	R264W	264	Missense	distal	6	no	15.215	14.392	EPSD	TCGA;ICGC;COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P10275	AR	P27361	MAPK3	S258	A253V	253	Missense	distal	-5	no	15.215	15.238	EPSD	TCGA;ICGC;COSMIC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P10275	AR	P27361	MAPK3	T282	E289K	289	Missense	distal	7	no	14.843	14.914	EPSD	TCGA;ICGC;COSMIC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P10275	AR	P27361	MAPK3	T282	R280C	280	Missense	proximal	-2	no	14.843	12.727	EPSD	TCGA;ICGC;COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P10275	AR	P27361	MAPK3	S310	E308K	308	Missense	proximal	-2	no	15.424	14.729	EPSD	TCGA;COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P10275	AR	P27361	MAPK3	S310	Y316H	316	Missense	distal	6	no	15.424	15.583	EPSD	TCGA;ICGC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P10275	AR	P27361	MAPK3	S516	P513S	513	Missense	distal	-3	no	17.503	17.494	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P10275	AR	P27361	MAPK3	S651	E645K	645	Missense	distal	-6	no	18.402	18.260	PhosphoSitePlus;EPSD	TCGA;ICGC;COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P10275	AR	P27361	MAPK3	T657	V662L	662	Missense	distal	5	no	9.892	9.888	EPSD	TCGA;ICGC;COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P10275	AR	P27361	MAPK3	T657	T661S	661	Missense	distal	4	no	9.892	10.005	EPSD	TCGA;ICGC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q15750	TAB1	P27361	MAPK3	S16	D20Y	20	Missense	distal	4	no	9.490	9.393	EPSD	TCGA	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q15750	TAB1	P27361	MAPK3	S16	W17C	17	Missense	proximal	1	no	9.490	2.086	EPSD	TCGA;ICGC;COSMIC	9.358	Loss
CMGC_MAPK_ERK1_MAPK3_ST	Q15750	TAB1	P27361	MAPK3	T431	E429K	429	Missense	proximal	-2	no	13.827	13.133	EPSD	TCGA;ICGC;COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q15750	TAB1	P27361	MAPK3	T431	A430T	430	Missense	proximal	-1	no	13.827	13.930	EPSD	TCGA;ICGC;COSMIC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q15750	TAB1	P27361	MAPK3	T431	T433I	433	Missense	proximal	2	no	13.827	13.803	EPSD	TCGA;ICGC;COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q15750	TAB1	P27361	MAPK3	S438	T433I	433	Missense	distal	-5	no	16.253	16.175	PhosphoSitePlus	TCGA;ICGC;COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q15750	TAB1	P27361	MAPK3	S492	V493M	493	Missense	proximal	1	no	10.093	5.836	EPSD	TCGA;ICGC;COSMIC	9.358	Loss
CMGC_MAPK_ERK1_MAPK3_ST	Q15750	TAB1	P27361	MAPK3	S492	L490P	490	Missense	proximal	-2	no	10.093	11.477	EPSD	TCGA;ICGC;COSMIC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P35228	NOS2	P27361	MAPK3	S37	D42G	42	Missense	distal	5	no	16.647	16.624	EPSD	TCGA;ICGC;COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P35228	NOS2	P27361	MAPK3	S56	V61M	61	Missense	distal	5	no	14.780	14.656	EPSD	TCGA;ICGC;COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P35228	NOS2	P27361	MAPK3	S56	P57L	57	Missense	proximal	1	no	14.780	5.742	EPSD	TCGA;ICGC;COSMIC	9.358	Loss
CMGC_MAPK_ERK1_MAPK3_ST	P35228	NOS2	P27361	MAPK3	S56	T63M	63	Missense	distal	7	no	14.780	15.112	EPSD	TCGA;ICGC;COSMIC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P35228	NOS2	P27361	MAPK3	S56	Q58K	58	Missense	proximal	2	no	14.780	14.786	EPSD	TCGA;ICGC;COSMIC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P35228	NOS2	P27361	MAPK3	S67	V61M	61	Missense	distal	-6	no	15.378	15.286	EPSD	TCGA;ICGC;COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P35228	NOS2	P27361	MAPK3	S67	K66M	66	Missense	proximal	-1	no	15.378	15.278	EPSD	TCGA;COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P35228	NOS2	P27361	MAPK3	S67	T63M	63	Missense	distal	-4	no	15.378	15.257	EPSD	TCGA;ICGC;COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P35228	NOS2	P27361	MAPK3	S67	S67F	67	Missense	central	0	yes	15.378	0.000	EPSD	TCGA;ICGC;COSMIC	9.358	Loss
CMGC_MAPK_ERK1_MAPK3_ST	P35228	NOS2	P27361	MAPK3	S67	V72G	72	Missense	distal	5	no	15.378	15.580	EPSD	TCGA;ICGC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P35228	NOS2	P27361	MAPK3	T77	P78S	78	Missense	proximal	1	no	15.836	6.782	EPSD	TCGA;ICGC	9.358	Loss
CMGC_MAPK_ERK1_MAPK3_ST	P35228	NOS2	P27361	MAPK3	T77	P82L	82	Missense	distal	5	no	15.836	15.608	EPSD	TCGA;ICGC;COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P35228	NOS2	P27361	MAPK3	T77	V72G	72	Missense	distal	-5	no	15.836	15.868	EPSD	TCGA;ICGC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P35228	NOS2	P27361	MAPK3	S80	P78S	78	Missense	proximal	-2	no	9.549	8.473	EPSD	TCGA;ICGC	9.358	Loss
CMGC_MAPK_ERK1_MAPK3_ST	P35228	NOS2	P27361	MAPK3	S80	P82L	82	Missense	proximal	2	no	9.549	9.528	EPSD	TCGA;ICGC;COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P35228	NOS2	P27361	MAPK3	S81	P78S	78	Missense	distal	-3	no	15.418	15.409	EPSD	TCGA;ICGC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P35228	NOS2	P27361	MAPK3	S81	P82L	82	Missense	proximal	1	no	15.418	6.380	EPSD	TCGA;ICGC;COSMIC	9.358	Loss
CMGC_MAPK_ERK1_MAPK3_ST	P35228	NOS2	P27361	MAPK3	S124	M120L	120	Missense	distal	-4	no	9.561	9.601	EPSD	TCGA;ICGC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P35228	NOS2	P27361	MAPK3	S124	G128A	128	Missense	distal	4	no	9.561	9.391	EPSD	TCGA;ICGC;COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P35228	NOS2	P27361	MAPK3	S124	P122L	122	Missense	proximal	-2	no	9.561	8.177	EPSD	TCGA;ICGC;COSMIC	9.358	Loss
CMGC_MAPK_ERK1_MAPK3_ST	P35228	NOS2	P27361	MAPK3	S124	M120I	120	Missense	distal	-4	no	9.561	9.582	EPSD	TCGA;ICGC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P35228	NOS2	P27361	MAPK3	S425	T432I	432	Missense	distal	7	no	9.208	9.488	EPSD	TCGA;ICGC;COSMIC	9.358	Gain
CMGC_MAPK_ERK1_MAPK3_ST	P35228	NOS2	P27361	MAPK3	S745	R740W	740	Missense	distal	-5	no	15.298	15.144	PhosphoSitePlus	TCGA;ICGC;COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P35228	NOS2	P27361	MAPK3	S898	I902F	902	Missense	distal	4	no	9.855	9.782	EPSD	TCGA;ICGC;COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P35228	NOS2	P27361	MAPK3	S898	S898F	898	Missense	central	0	yes	9.855	0.000	EPSD	TCGA;ICGC;COSMIC	9.358	Loss
CMGC_MAPK_ERK1_MAPK3_ST	P35228	NOS2	P27361	MAPK3	S911	S912F	912	Missense	proximal	1	no	7.048	9.888	EPSD	TCGA;ICGC;COSMIC	9.358	Gain
CMGC_MAPK_ERK1_MAPK3_ST	P13631	RARG	P27361	MAPK3	S36	S43I	43	Missense	distal	7	no	16.532	16.930	EPSD	TCGA;ICGC;COSMIC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P13631	RARG	P27361	MAPK3	S36	M41I	41	Missense	distal	5	no	16.532	16.530	EPSD	TCGA;ICGC;COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P13631	RARG	P27361	MAPK3	S36	G35R	35	Missense	proximal	-1	no	16.532	16.556	EPSD	TCGA;ICGC;COSMIC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P13631	RARG	P27361	MAPK3	S43	S43I	43	Missense	central	0	yes	14.622	0.000	EPSD	TCGA;ICGC;COSMIC	9.358	Loss
CMGC_MAPK_ERK1_MAPK3_ST	P13631	RARG	P27361	MAPK3	S43	M41I	41	Missense	proximal	-2	no	14.622	15.538	EPSD	TCGA;ICGC;COSMIC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P13631	RARG	P27361	MAPK3	S43	P44L	44	Missense	proximal	1	no	14.622	5.584	EPSD	TCGA;ICGC;COSMIC	9.358	Loss
CMGC_MAPK_ERK1_MAPK3_ST	P13631	RARG	P27361	MAPK3	S77	P82L	82	Missense	distal	5	no	18.579	18.351	EPSD	TCGA;ICGC;COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P13631	RARG	P27361	MAPK3	S77	S77L	77	Missense	central	0	yes	18.579	0.000	EPSD	TCGA;ICGC;COSMIC	9.358	Loss
CMGC_MAPK_ERK1_MAPK3_ST	P13631	RARG	P27361	MAPK3	S77	P82A	82	Missense	distal	5	no	18.579	18.366	EPSD	TCGA;COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P13631	RARG	P27361	MAPK3	S79	P82L	82	Missense	distal	3	no	17.409	17.372	PhosphoSitePlus	TCGA;ICGC;COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P13631	RARG	P27361	MAPK3	S79	S77L	77	Missense	proximal	-2	no	17.409	17.101	PhosphoSitePlus	TCGA;ICGC;COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P13631	RARG	P27361	MAPK3	S79	P82A	82	Missense	distal	3	no	17.409	17.360	PhosphoSitePlus	TCGA;COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P13631	RARG	P27361	MAPK3	S176	E174K	174	Missense	proximal	-2	no	16.552	15.858	EPSD	TCGA;ICGC;COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P13631	RARG	P27361	MAPK3	S176	E173K	173	Missense	distal	-3	no	16.552	16.521	EPSD	TCGA;COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P13631	RARG	P27361	MAPK3	S176	S179N	179	Missense	distal	3	no	16.552	16.531	EPSD	TCGA;COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P13631	RARG	P27361	MAPK3	S179	E174K	174	Missense	distal	-5	no	13.070	13.058	EPSD	TCGA;ICGC;COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P13631	RARG	P27361	MAPK3	S179	E173K	173	Missense	distal	-6	no	13.070	12.928	EPSD	TCGA;COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P13631	RARG	P27361	MAPK3	S179	S179N	179	Missense	central	0	yes	13.070	0.000	EPSD	TCGA;COSMIC	9.358	Loss
CMGC_MAPK_ERK1_MAPK3_ST	P13631	RARG	P27361	MAPK3	S436	S437R	437	Missense	proximal	1	no	10.454	10.007	EPSD	TCGA;ICGC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P13631	RARG	P27361	MAPK3	S436	P442S	442	Missense	distal	6	no	10.454	10.584	EPSD	TCGA;COSMIC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P13631	RARG	P27361	MAPK3	S437	P442S	442	Missense	distal	5	no	9.340	9.383	EPSD	TCGA;COSMIC	9.358	Gain
CMGC_MAPK_ERK1_MAPK3_ST	P33981	TTK	P27361	MAPK3	S214	G217S	217	Missense	distal	3	no	10.029	10.044	EPSD	TCGA;ICGC;COSMIC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P33981	TTK	P27361	MAPK3	S281	T288I	288	Missense	distal	7	no	17.437	17.717	EPSD	TCGA;ICGC;COSMIC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P33981	TTK	P27361	MAPK3	T453	S449Y	449	Missense	distal	-4	no	10.836	10.733	EPSD	TCGA;COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P33981	TTK	P27361	MAPK3	T468	P469L	469	Missense	proximal	1	no	15.750	6.712	EPSD	TCGA;COSMIC;GDSC	9.358	Loss
CMGC_MAPK_ERK1_MAPK3_ST	P33981	TTK	P27361	MAPK3	T468	K472N	472	Missense	distal	4	no	15.750	15.742	EPSD	TCGA	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P33981	TTK	P27361	MAPK3	S582	L575W	575	Missense	distal	-7	no	9.807	9.991	EPSD	TCGA;COSMIC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P33981	TTK	P27361	MAPK3	S582	L575F	575	Missense	distal	-7	no	9.807	9.881	EPSD	TCGA;COSMIC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P33981	TTK	P27361	MAPK3	S582	S582I	582	Missense	central	0	yes	9.807	0.000	EPSD	TCGA;COSMIC	9.358	Loss
CMGC_MAPK_ERK1_MAPK3_ST	P33981	TTK	P27361	MAPK3	S582	S582G	582	Missense	central	0	yes	9.807	0.000	EPSD	TCGA;COSMIC	9.358	Loss
CMGC_MAPK_ERK1_MAPK3_ST	P33981	TTK	P27361	MAPK3	S821	G814C	814	Missense	distal	-7	no	15.858	16.090	PhosphoSitePlus	TCGA;COSMIC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P33981	TTK	P27361	MAPK3	S821	S824F	824	Missense	distal	3	no	15.858	15.794	PhosphoSitePlus	TCGA;COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P33981	TTK	P27361	MAPK3	S821	L816R	816	Missense	distal	-5	no	15.858	15.872	PhosphoSitePlus	TCGA;COSMIC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P33981	TTK	P27361	MAPK3	S821	S821Y	821	Missense	central	0	yes	15.858	0.000	PhosphoSitePlus	TCGA;COSMIC	9.358	Loss
CMGC_MAPK_ERK1_MAPK3_ST	P33981	TTK	P27361	MAPK3	S844	G839S	839	Missense	distal	-5	no	10.791	10.834	EPSD	TCGA;COSMIC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P33981	TTK	P27361	MAPK3	T849	R854G	854	Missense	distal	5	no	11.635	11.714	EPSD	TCGA;COSMIC;CCLE	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P33981	TTK	P27361	MAPK3	T849	R854K	854	Missense	distal	5	no	11.635	11.627	EPSD	TCGA;COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q86UR1	NOXA1	P27361	MAPK3	S239	S239F	239	Missense	central	0	yes	14.287	0.000	EPSD	TCGA;ICGC	9.358	Loss
CMGC_MAPK_ERK1_MAPK3_ST	Q86UR1	NOXA1	P27361	MAPK3	S282	G289E	289	Missense	distal	7	no	16.898	16.863	PhosphoSitePlus	TCGA;ICGC;COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q86UR1	NOXA1	P27361	MAPK3	S409	A412T	412	Missense	distal	3	no	10.299	10.330	EPSD	TCGA;ICGC;COSMIC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q86UR1	NOXA1	P27361	MAPK3	S470	R466Q	466	Missense	distal	-4	no	14.527	14.537	EPSD	TCGA;COSMIC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	O60331	PIP5K1C	P27361	MAPK3	S355	L353H	353	Missense	proximal	-2	no	9.471	9.627	EPSD	TCGA;ICGC;COSMIC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	O60331	PIP5K1C	P27361	MAPK3	S355	K351N	351	Missense	distal	-4	no	9.471	9.494	EPSD	TCGA;ICGC;COSMIC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	O60331	PIP5K1C	P27361	MAPK3	S402	Y403F	403	Missense	proximal	1	no	8.791	9.625	EPSD	TCGA;ICGC;COSMIC	9.358	Gain
CMGC_MAPK_ERK1_MAPK3_ST	O60331	PIP5K1C	P27361	MAPK3	S453	P454A	454	Missense	proximal	1	no	13.524	4.284	EPSD	TCGA;ICGC;COSMIC	9.358	Loss
CMGC_MAPK_ERK1_MAPK3_ST	O60331	PIP5K1C	P27361	MAPK3	S453	R459C	459	Missense	distal	6	no	13.524	12.898	EPSD	TCGA;ICGC;COSMIC;CCLE	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	O60331	PIP5K1C	P27361	MAPK3	S515	C511Y	511	Missense	distal	-4	no	11.215	11.350	EPSD	TCGA;ICGC;COSMIC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	O60331	PIP5K1C	P27361	MAPK3	S539	S541L	541	Missense	proximal	2	no	16.757	16.733	EPSD	TCGA;ICGC;COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	O60331	PIP5K1C	P27361	MAPK3	S539	S534F	534	Missense	distal	-5	no	16.757	16.622	EPSD	TCGA;ICGC;COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	O60331	PIP5K1C	P27361	MAPK3	S539	P540S	540	Missense	proximal	1	no	16.757	7.703	EPSD	TCGA;ICGC;COSMIC	9.358	Loss
CMGC_MAPK_ERK1_MAPK3_ST	O60331	PIP5K1C	P27361	MAPK3	S539	R538Q	538	Missense	proximal	-1	no	16.757	16.718	EPSD	TCGA;ICGC;COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	O60331	PIP5K1C	P27361	MAPK3	S539	R538W	538	Missense	proximal	-1	no	16.757	16.518	EPSD	TCGA;ICGC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	O60331	PIP5K1C	P27361	MAPK3	T553	R551Q	551	Missense	proximal	-2	no	10.824	10.460	EPSD	TCGA;ICGC;COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	O60331	PIP5K1C	P27361	MAPK3	T553	R548W	548	Missense	distal	-5	no	10.824	10.670	EPSD	TCGA;ICGC;COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	O60331	PIP5K1C	P27361	MAPK3	T553	R548Q	548	Missense	distal	-5	no	10.824	10.816	EPSD	TCGA;ICGC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	O60331	PIP5K1C	P27361	MAPK3	T553	R551W	551	Missense	proximal	-2	no	10.824	8.927	EPSD	TCGA;ICGC;COSMIC	9.358	Loss
CMGC_MAPK_ERK1_MAPK3_ST	O60331	PIP5K1C	P27361	MAPK3	S650	D643N	643	Missense	distal	-7	no	18.963	18.988	PhosphoSitePlus	TCGA;ICGC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	O60331	PIP5K1C	P27361	MAPK3	S650	E644D	644	Missense	distal	-6	no	18.963	18.919	PhosphoSitePlus	TCGA;ICGC;COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	O60331	PIP5K1C	P27361	MAPK3	S650	Y654C	654	Missense	distal	4	no	18.963	18.676	PhosphoSitePlus	TCGA;ICGC;COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	O60331	PIP5K1C	P27361	MAPK3	S650	H653Y	653	Missense	distal	3	no	18.963	18.947	PhosphoSitePlus	TCGA;ICGC;COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	O60331	PIP5K1C	P27361	MAPK3	S650	Y649H	649	Missense	proximal	-1	no	18.963	19.001	PhosphoSitePlus	TCGA;ICGC;COSMIC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	O60331	PIP5K1C	P27361	MAPK3	S650	A656V	656	Missense	distal	6	no	18.963	19.050	PhosphoSitePlus	TCGA;ICGC;COSMIC;CCLE	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	O60331	PIP5K1C	P27361	MAPK3	S650	S646C	646	Missense	distal	-4	no	18.963	18.725	PhosphoSitePlus	TCGA;ICGC;COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	O60331	PIP5K1C	P27361	MAPK3	S655	Y654C	654	Missense	proximal	-1	no	9.580	9.430	EPSD	TCGA;ICGC;COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	O60331	PIP5K1C	P27361	MAPK3	S655	H653Y	653	Missense	proximal	-2	no	9.580	9.498	EPSD	TCGA;ICGC;COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	O60331	PIP5K1C	P27361	MAPK3	S655	Y649H	649	Missense	distal	-6	no	9.580	9.668	EPSD	TCGA;ICGC;COSMIC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	O60331	PIP5K1C	P27361	MAPK3	S655	A658P	658	Missense	distal	3	no	9.580	9.628	EPSD	TCGA;ICGC;COSMIC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	O60331	PIP5K1C	P27361	MAPK3	S655	A656V	656	Missense	proximal	1	no	9.580	9.397	EPSD	TCGA;ICGC;COSMIC;CCLE	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	O60331	PIP5K1C	P27361	MAPK3	S662	A658P	658	Missense	distal	-4	no	12.268	12.373	EPSD	TCGA;ICGC;COSMIC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	O60331	PIP5K1C	P27361	MAPK3	S662	A656V	656	Missense	distal	-6	no	12.268	12.255	EPSD	TCGA;ICGC;COSMIC;CCLE	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P27824	CANX	P27361	MAPK3	S55	P53H	53	Missense	proximal	-2	no	18.319	17.091	EPSD	TCGA;COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P27824	CANX	P27361	MAPK3	S583	D577G	577	Missense	distal	-6	no	18.094	18.093	PhosphoSitePlus	TCGA;COSMIC;GDSC;CCLE	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P27824	CANX	P27361	MAPK3	S583	D577Y	577	Missense	distal	-6	no	18.094	17.901	PhosphoSitePlus	TCGA;COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q12931	TRAP1	P27361	MAPK3	S367	R368H	368	Missense	proximal	1	no	8.690	10.434	EPSD	TCGA;ICGC;COSMIC;GDSC	9.358	Gain
CMGC_MAPK_ERK1_MAPK3_ST	Q12931	TRAP1	P27361	MAPK3	S472	S472F	472	Missense	central	0	yes	9.483	0.000	EPSD	TCGA;ICGC;COSMIC	9.358	Loss
CMGC_MAPK_ERK1_MAPK3_ST	Q12931	TRAP1	P27361	MAPK3	S472	S477F	477	Missense	distal	5	no	9.483	9.058	EPSD	TCGA;ICGC;COSMIC	9.358	Loss
CMGC_MAPK_ERK1_MAPK3_ST	Q12931	TRAP1	P27361	MAPK3	S511	M517T	517	Missense	distal	6	no	13.698	14.193	PhosphoSitePlus	TCGA;ICGC;COSMIC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q12931	TRAP1	P27361	MAPK3	S568	A571T	571	Missense	distal	3	no	12.835	12.866	EPSD	TCGA;ICGC;COSMIC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q92908	GATA6	P27361	MAPK3	T34	P36L	36	Missense	proximal	2	no	17.386	17.364	EPSD	TCGA;ICGC;COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q92908	GATA6	P27361	MAPK3	S37	P36L	36	Missense	proximal	-1	no	19.186	19.092	EPSD	TCGA;ICGC;COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q92908	GATA6	P27361	MAPK3	T62	A69V	69	Missense	distal	7	no	10.474	10.446	EPSD	TCGA;ICGC;COSMIC;GDSC;CCLE	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q92908	GATA6	P27361	MAPK3	T515	S520C	520	Missense	distal	5	no	18.227	17.704	EPSD	TCGA;ICGC;COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q92908	GATA6	P27361	MAPK3	T515	P516L	516	Missense	proximal	1	no	18.227	9.189	EPSD	TCGA;ICGC;COSMIC	9.358	Loss
CMGC_MAPK_ERK1_MAPK3_ST	Q92908	GATA6	P27361	MAPK3	S531	N529K	529	Missense	proximal	-2	no	17.038	16.718	EPSD	TCGA;ICGC;COSMIC;GDSC;CCLE	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q92908	GATA6	P27361	MAPK3	S531	N529H	529	Missense	proximal	-2	no	17.038	17.831	EPSD	TCGA;ICGC;COSMIC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q92908	GATA6	P27361	MAPK3	S531	A538T	538	Missense	distal	7	no	17.038	16.811	EPSD	TCGA;ICGC;COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q92908	GATA6	P27361	MAPK3	T534	N529K	529	Missense	distal	-5	no	9.798	9.792	EPSD	TCGA;ICGC;COSMIC;GDSC;CCLE	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q92908	GATA6	P27361	MAPK3	T534	N529H	529	Missense	distal	-5	no	9.798	9.802	EPSD	TCGA;ICGC;COSMIC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q92908	GATA6	P27361	MAPK3	T534	G540R	540	Missense	distal	6	no	9.798	9.788	EPSD	TCGA;ICGC;COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q92908	GATA6	P27361	MAPK3	T534	A538T	538	Missense	distal	4	no	9.798	10.016	EPSD	TCGA;ICGC;COSMIC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q86UC2	RSPH3	P27361	MAPK3	T243	R250T	250	Missense	distal	7	no	16.075	16.024	EPSD	TCGA;ICGC;COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q86UC2	RSPH3	P27361	MAPK3	T286	D282G	282	Missense	distal	-4	no	16.241	16.238	PhosphoSitePlus	TCGA;ICGC;COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q86UC2	RSPH3	P27361	MAPK3	S553	M550I	550	Missense	distal	-3	no	11.104	11.120	EPSD	TCGA;COSMIC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q9UQC2	GAB2	P27361	MAPK3	S140	S140F	140	Missense	central	0	yes	9.973	0.000	EPSD	TCGA;COSMIC	9.358	Loss
CMGC_MAPK_ERK1_MAPK3_ST	Q9UQC2	GAB2	P27361	MAPK3	S141	S140F	140	Missense	proximal	-1	no	18.281	18.077	EPSD	TCGA;COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q9UQC2	GAB2	P27361	MAPK3	S147	S140F	140	Missense	distal	-7	no	9.265	9.484	EPSD	TCGA;COSMIC	9.358	Gain
CMGC_MAPK_ERK1_MAPK3_ST	Q9UQC2	GAB2	P27361	MAPK3	T171	P175H	175	Missense	distal	4	no	9.953	9.862	EPSD	TCGA	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q9UQC2	GAB2	P27361	MAPK3	T265	R270H	270	Missense	distal	5	no	9.756	9.792	EPSD	TCGA;COSMIC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q9UQC2	GAB2	P27361	MAPK3	T265	T265N	265	Missense	central	0	yes	9.756	0.000	EPSD	TCGA;COSMIC;CCLE	9.358	Loss
CMGC_MAPK_ERK1_MAPK3_ST	Q9UQC2	GAB2	P27361	MAPK3	T265	T265I	265	Missense	central	0	yes	9.756	0.000	EPSD	TCGA;COSMIC	9.358	Loss
CMGC_MAPK_ERK1_MAPK3_ST	Q9UQC2	GAB2	P27361	MAPK3	T265	F261S	261	Missense	distal	-4	no	9.756	9.945	EPSD	TCGA	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q9UQC2	GAB2	P27361	MAPK3	T294	T294N	294	Missense	central	0	yes	9.384	0.000	EPSD	TCGA;COSMIC	9.358	Loss
CMGC_MAPK_ERK1_MAPK3_ST	Q9UQC2	GAB2	P27361	MAPK3	S368	S368N	368	Missense	central	0	yes	16.275	0.000	EPSD	TCGA;COSMIC	9.358	Loss
CMGC_MAPK_ERK1_MAPK3_ST	Q9UQC2	GAB2	P27361	MAPK3	S381	V382F	382	Missense	proximal	1	no	7.065	10.273	EPSD	TCGA;COSMIC	9.358	Gain
CMGC_MAPK_ERK1_MAPK3_ST	Q9UQC2	GAB2	P27361	MAPK3	S404	S405F	405	Missense	proximal	1	no	7.054	9.894	EPSD	TCGA;COSMIC	9.358	Gain
CMGC_MAPK_ERK1_MAPK3_ST	Q9UQC2	GAB2	P27361	MAPK3	S480	I477N	477	Missense	distal	-3	no	17.922	17.989	EPSD	TCGA;COSMIC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q9UQC2	GAB2	P27361	MAPK3	S543	D537N	537	Missense	distal	-6	no	15.174	15.112	EPSD	TCGA;COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q9UQC2	GAB2	P27361	MAPK3	S623	P621Q	621	Missense	proximal	-2	no	18.019	16.255	PhosphoSitePlus	TCGA;COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q9UQC2	GAB2	P27361	MAPK3	S623	A616D	616	Missense	distal	-7	no	18.019	17.911	PhosphoSitePlus	TCGA;COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q9UQC2	GAB2	P27361	MAPK3	S625	P621Q	621	Missense	distal	-4	no	16.490	16.451	EPSD	TCGA;COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P10828	THRB	P27361	MAPK3	T2	P3L	3	Missense	proximal	1	no	12.355	3.317	EPSD	TCGA;ICGC;COSMIC	9.358	Loss
CMGC_MAPK_ERK1_MAPK3_ST	P10828	THRB	P27361	MAPK3	T2	T7I	7	Missense	distal	5	no	12.355	12.098	EPSD	TCGA;ICGC;COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P10828	THRB	P27361	MAPK3	S55	S55L	55	Missense	central	0	yes	16.674	0.000	EPSD	TCGA;ICGC;COSMIC;GDSC;CCLE	9.358	Loss
CMGC_MAPK_ERK1_MAPK3_ST	P10828	THRB	P27361	MAPK3	S55	P56L	56	Missense	proximal	1	no	16.674	7.636	EPSD	TCGA;ICGC;COSMIC	9.358	Loss
CMGC_MAPK_ERK1_MAPK3_ST	P10828	THRB	P27361	MAPK3	S55	H57Y	57	Missense	proximal	2	no	16.674	16.667	EPSD	TCGA;ICGC;COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P10828	THRB	P27361	MAPK3	S55	E52G	52	Missense	distal	-3	no	16.674	16.661	EPSD	TCGA;ICGC;COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P10828	THRB	P27361	MAPK3	S142	G149E	149	Missense	distal	7	no	10.118	10.083	PhosphoSitePlus	TCGA;ICGC;COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P10828	THRB	P27361	MAPK3	S142	S144F	144	Missense	proximal	2	no	10.118	10.067	PhosphoSitePlus	TCGA;ICGC;COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P10828	THRB	P27361	MAPK3	S142	P141S	141	Missense	proximal	-1	no	10.118	10.112	PhosphoSitePlus	TCGA;ICGC;COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P10828	THRB	P27361	MAPK3	S142	L139I	139	Missense	distal	-3	no	10.118	10.082	PhosphoSitePlus	TCGA;ICGC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P10301	RRAS	P27361	MAPK3	S201	K208N	208	Missense	distal	7	no	20.640	20.631	PhosphoSitePlus	TCGA;ICGC;COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P10301	RRAS	P27361	MAPK3	S201	P200L	200	Missense	proximal	-1	no	20.640	20.546	PhosphoSitePlus	TCGA;ICGC;COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P10301	RRAS	P27361	MAPK3	S201	P200S	200	Missense	proximal	-1	no	20.640	20.635	PhosphoSitePlus	TCGA;ICGC;COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P10301	RRAS	P27361	MAPK3	S204	K208N	208	Missense	distal	4	no	11.768	11.760	EPSD	TCGA;ICGC;COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P10301	RRAS	P27361	MAPK3	S204	P200L	200	Missense	distal	-4	no	11.768	11.656	EPSD	TCGA;ICGC;COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P10301	RRAS	P27361	MAPK3	S204	P200S	200	Missense	distal	-4	no	11.768	11.796	EPSD	TCGA;ICGC;COSMIC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q92797	SYMPK	P27361	MAPK3	S16	T10A	10	Missense	distal	-6	no	10.950	10.802	EPSD	TCGA;ICGC;COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q92797	SYMPK	P27361	MAPK3	S16	A15T	15	Missense	proximal	-1	no	10.950	11.054	EPSD	TCGA;ICGC;COSMIC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q92797	SYMPK	P27361	MAPK3	S195	D200N	200	Missense	distal	5	no	16.815	16.735	EPSD	TCGA;ICGC;COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q92797	SYMPK	P27361	MAPK3	S195	L194M	194	Missense	proximal	-1	no	16.815	16.749	EPSD	TCGA;ICGC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q92797	SYMPK	P27361	MAPK3	S195	R197H	197	Missense	proximal	2	no	16.815	16.812	EPSD	TCGA;ICGC;COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q92797	SYMPK	P27361	MAPK3	S195	I191V	191	Missense	distal	-4	no	16.815	16.823	EPSD	TCGA;ICGC;COSMIC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q92797	SYMPK	P27361	MAPK3	S870	R876Q	876	Missense	distal	6	no	18.666	18.597	EPSD	TCGA;ICGC;COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q92797	SYMPK	P27361	MAPK3	S870	R876W	876	Missense	distal	6	no	18.666	17.843	EPSD	TCGA;ICGC;COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q92797	SYMPK	P27361	MAPK3	S938	P939L	939	Missense	proximal	1	no	16.166	7.128	EPSD	TCGA;ICGC;GDSC;CCLE	9.358	Loss
CMGC_MAPK_ERK1_MAPK3_ST	Q92797	SYMPK	P27361	MAPK3	S1081	A1077V	1077	Missense	distal	-4	no	9.423	9.403	EPSD	TCGA;ICGC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q92797	SYMPK	P27361	MAPK3	T1083	A1077V	1077	Missense	distal	-6	no	16.399	16.386	EPSD	TCGA;ICGC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q92797	SYMPK	P27361	MAPK3	S1185	E1186Q	1186	Missense	proximal	1	no	8.747	10.051	EPSD	TCGA;ICGC;COSMIC	9.358	Gain
CMGC_MAPK_ERK1_MAPK3_ST	Q92797	SYMPK	P27361	MAPK3	S1243	P1244L	1244	Missense	proximal	1	no	17.169	8.131	EPSD	TCGA;ICGC;COSMIC	9.358	Loss
CMGC_MAPK_ERK1_MAPK3_ST	Q92797	SYMPK	P27361	MAPK3	T1246	P1244L	1244	Missense	proximal	-2	no	9.525	8.140	EPSD	TCGA;ICGC;COSMIC	9.358	Loss
CMGC_MAPK_ERK1_MAPK3_ST	Q92797	SYMPK	P27361	MAPK3	T1257	P1258L	1258	Missense	proximal	1	no	16.741	7.703	PhosphoSitePlus	TCGA;ICGC;COSMIC	9.358	Loss
CMGC_MAPK_ERK1_MAPK3_ST	Q92797	SYMPK	P27361	MAPK3	S1259	P1258L	1258	Missense	proximal	-1	no	18.473	18.378	EPSD	TCGA;ICGC;COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q9NRF2	SH2B1	P27361	MAPK3	S88	P94L	94	Missense	distal	6	no	17.328	17.101	EPSD	TCGA;ICGC;COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q9NRF2	SH2B1	P27361	MAPK3	S88	P90T	90	Missense	proximal	2	no	17.328	17.319	EPSD	TCGA;ICGC;COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q9NRF2	SH2B1	P27361	MAPK3	S96	P94L	94	Missense	proximal	-2	no	16.625	15.241	PhosphoSitePlus	TCGA;ICGC;COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q9NRF2	SH2B1	P27361	MAPK3	S96	A99V	99	Missense	distal	3	no	16.625	16.632	PhosphoSitePlus	TCGA;ICGC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q9NRF2	SH2B1	P27361	MAPK3	S96	P90T	90	Missense	distal	-6	no	16.625	16.541	PhosphoSitePlus	TCGA;ICGC;COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q9NRF2	SH2B1	P27361	MAPK3	S96	S102L	102	Missense	distal	6	no	16.625	16.269	PhosphoSitePlus	TCGA;ICGC;COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q9NRF2	SH2B1	P27361	MAPK3	S102	A99V	99	Missense	distal	-3	no	16.228	16.247	EPSD	TCGA;ICGC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q9NRF2	SH2B1	P27361	MAPK3	S102	S102L	102	Missense	central	0	yes	16.228	0.000	EPSD	TCGA;ICGC;COSMIC	9.358	Loss
CMGC_MAPK_ERK1_MAPK3_ST	Q9NRF2	SH2B1	P27361	MAPK3	S144	T143A	143	Missense	proximal	-1	no	9.509	9.406	EPSD	TCGA;ICGC;COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q9NRF2	SH2B1	P27361	MAPK3	S219	D216H	216	Missense	distal	-3	no	15.125	15.116	EPSD	TCGA;ICGC;COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q9NRF2	SH2B1	P27361	MAPK3	S384	R386C	386	Missense	proximal	2	no	13.920	13.871	EPSD	TCGA;ICGC;COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P53355	DAPK1	P27361	MAPK3	T180	A185T	185	Missense	distal	5	no	11.848	11.968	EPSD	TCGA;ICGC;COSMIC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P53355	DAPK1	P27361	MAPK3	T180	T180I	180	Missense	central	0	yes	11.848	0.000	EPSD	TCGA;ICGC;COSMIC	9.358	Loss
CMGC_MAPK_ERK1_MAPK3_ST	P53355	DAPK1	P27361	MAPK3	S321	M328V	328	Missense	distal	7	no	9.981	9.848	EPSD	TCGA;ICGC;COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P53355	DAPK1	P27361	MAPK3	S321	R317I	317	Missense	distal	-4	no	9.981	9.898	EPSD	TCGA;ICGC;COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P53355	DAPK1	P27361	MAPK3	S342	A347S	347	Missense	distal	5	no	11.902	12.157	EPSD	TCGA;ICGC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P53355	DAPK1	P27361	MAPK3	T612	G610R	610	Missense	proximal	-2	no	13.278	13.994	EPSD	TCGA;ICGC;COSMIC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P53355	DAPK1	P27361	MAPK3	S734	P733H	733	Missense	proximal	-1	no	20.876	20.831	PhosphoSitePlus	TCGA	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P53355	DAPK1	P27361	MAPK3	S734	P735L	735	Missense	proximal	1	no	20.876	11.838	PhosphoSitePlus	TCGA;ICGC;COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P53355	DAPK1	P27361	MAPK3	T1053	V1051M	1051	Missense	proximal	-2	no	14.530	13.430	EPSD	TCGA;ICGC;COSMIC;GDSC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P53355	DAPK1	P27361	MAPK3	S1115	R1114H	1114	Missense	proximal	-1	no	10.334	10.337	EPSD	TCGA;ICGC;COSMIC;CCLE	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P53355	DAPK1	P27361	MAPK3	S1115	D1118N	1118	Missense	distal	3	no	10.334	10.324	EPSD	TCGA;ICGC;COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P53355	DAPK1	P27361	MAPK3	S1425	S1429F	1429	Missense	distal	4	no	9.567	9.152	EPSD	TCGA;ICGC;COSMIC	9.358	Loss
CMGC_MAPK_ERK1_MAPK3_ST	Q16254	E2F4	P27361	MAPK3	T14	K20T	20	Missense	distal	6	no	17.274	17.327	EPSD	TCGA;ICGC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q16254	E2F4	P27361	MAPK3	T14	H18R	18	Missense	distal	4	no	17.274	17.268	EPSD	TCGA;ICGC;COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q16254	E2F4	P27361	MAPK3	S21	K20T	20	Missense	proximal	-1	no	9.905	9.930	EPSD	TCGA;ICGC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q16254	E2F4	P27361	MAPK3	S21	H18R	18	Missense	distal	-3	no	9.905	9.899	EPSD	TCGA;ICGC;COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q16254	E2F4	P27361	MAPK3	S202	K197N	197	Missense	distal	-5	no	13.160	13.166	EPSD	TCGA;ICGC;COSMIC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q16254	E2F4	P27361	MAPK3	S218	S218N	218	Missense	central	0	yes	16.771	0.000	EPSD	TCGA;ICGC;COSMIC	9.358	Loss
CMGC_MAPK_ERK1_MAPK3_ST	Q16254	E2F4	P27361	MAPK3	T224	L228V	228	Missense	distal	4	no	16.649	16.629	EPSD	TCGA;ICGC;COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q16254	E2F4	P27361	MAPK3	T224	P227L	227	Missense	distal	3	no	16.649	16.613	EPSD	TCGA;ICGC;COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q16254	E2F4	P27361	MAPK3	T224	P231L	231	Missense	distal	7	no	16.649	16.842	EPSD	TCGA;ICGC;COSMIC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q16254	E2F4	P27361	MAPK3	T224	S218N	218	Missense	distal	-6	no	16.649	16.527	EPSD	TCGA;ICGC;COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q16254	E2F4	P27361	MAPK3	S244	S244I	244	Missense	central	0	yes	16.884	0.000	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	9.358	Loss
CMGC_MAPK_ERK1_MAPK3_ST	Q16254	E2F4	P27361	MAPK3	T248	P253S	253	Missense	distal	5	no	12.642	12.685	EPSD	TCGA;ICGC;COSMIC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q16254	E2F4	P27361	MAPK3	T248	S244I	244	Missense	distal	-4	no	12.642	12.483	EPSD	TCGA;ICGC;COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q16254	E2F4	P27361	MAPK3	S384	P385S	385	Missense	proximal	1	no	17.924	8.870	PhosphoSitePlus;EPSD	TCGA;ICGC;COSMIC	9.358	Loss
CMGC_MAPK_ERK1_MAPK3_ST	Q16254	E2F4	P27361	MAPK3	S384	D389N	389	Missense	distal	5	no	17.924	17.843	PhosphoSitePlus;EPSD	TCGA;ICGC;COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q16254	E2F4	P27361	MAPK3	S384	L383V	383	Missense	proximal	-1	no	17.924	17.928	PhosphoSitePlus;EPSD	TCGA;ICGC;COSMIC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q16254	E2F4	P27361	MAPK3	S384	R382H	382	Missense	proximal	-2	no	17.924	18.096	PhosphoSitePlus;EPSD	TCGA;ICGC;COSMIC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q8NET8	TRPV3	P27361	MAPK3	T35	A41T	41	Missense	distal	6	no	13.858	14.228	EPSD	TCGA;ICGC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q8NET8	TRPV3	P27361	MAPK3	T35	P31Q	31	Missense	distal	-4	no	13.858	13.818	EPSD	TCGA;ICGC;COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q8NET8	TRPV3	P27361	MAPK3	T35	S40I	40	Missense	distal	5	no	13.858	13.465	EPSD	TCGA;ICGC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q8NET8	TRPV3	P27361	MAPK3	T264	T264M	264	Missense	central	0	yes	13.493	0.000	PhosphoSitePlus	TCGA;ICGC;COSMIC;GDSC;CCLE	9.358	Loss
CMGC_MAPK_ERK1_MAPK3_ST	Q8NET8	TRPV3	P27361	MAPK3	T264	E257Q	257	Missense	distal	-7	no	13.493	13.543	PhosphoSitePlus	TCGA;ICGC;COSMIC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q8NET8	TRPV3	P27361	MAPK3	T264	G258C	258	Missense	distal	-6	no	13.493	12.996	PhosphoSitePlus	TCGA;ICGC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P41182	BCL6	P27361	MAPK3	S250	R244L	244	Missense	distal	-6	no	16.503	16.331	EPSD	TCGA;ICGC;COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P41182	BCL6	P27361	MAPK3	S260	P261R	261	Missense	proximal	1	no	15.759	6.259	EPSD	TCGA;ICGC;COSMIC	9.358	Loss
CMGC_MAPK_ERK1_MAPK3_ST	P41182	BCL6	P27361	MAPK3	S260	I265N	265	Missense	distal	5	no	15.759	16.030	EPSD	TCGA;ICGC;COSMIC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P41182	BCL6	P27361	MAPK3	S330	K326N	326	Missense	distal	-4	no	15.960	15.983	EPSD	TCGA;ICGC;COSMIC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P41182	BCL6	P27361	MAPK3	S333	K326N	326	Missense	distal	-7	no	17.639	17.623	PhosphoSitePlus;EPSD	TCGA;ICGC;COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P41182	BCL6	P27361	MAPK3	S343	S349N	349	Missense	distal	6	no	20.314	20.085	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P41182	BCL6	P27361	MAPK3	S343	E346K	346	Missense	distal	3	no	20.314	20.303	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P41182	BCL6	P27361	MAPK3	S361	A364V	364	Missense	distal	3	no	16.217	16.224	EPSD	TCGA;ICGC;COSMIC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P41182	BCL6	P27361	MAPK3	S361	K365N	365	Missense	distal	4	no	16.217	16.209	EPSD	TCGA;ICGC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P41182	BCL6	P27361	MAPK3	S361	P367L	367	Missense	distal	6	no	16.217	15.990	EPSD	TCGA;ICGC;COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P41182	BCL6	P27361	MAPK3	S366	A364V	364	Missense	proximal	-2	no	15.222	15.919	EPSD	TCGA;ICGC;COSMIC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P41182	BCL6	P27361	MAPK3	S366	K365N	365	Missense	proximal	-1	no	15.222	15.229	EPSD	TCGA;ICGC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P41182	BCL6	P27361	MAPK3	S366	P367L	367	Missense	proximal	1	no	15.222	6.184	EPSD	TCGA;ICGC;COSMIC	9.358	Loss
CMGC_MAPK_ERK1_MAPK3_ST	P41182	BCL6	P27361	MAPK3	S404	R406Q	406	Missense	proximal	2	no	15.477	15.468	EPSD	TCGA;ICGC;COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P41182	BCL6	P27361	MAPK3	S404	P405L	405	Missense	proximal	1	no	15.477	6.439	EPSD	TCGA;ICGC;COSMIC	9.358	Loss
CMGC_MAPK_ERK1_MAPK3_ST	P41182	BCL6	P27361	MAPK3	S427	L425R	425	Missense	proximal	-2	no	16.223	16.208	EPSD	TCGA;ICGC;COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P41182	BCL6	P27361	MAPK3	S427	A433V	433	Missense	distal	6	no	16.223	16.311	EPSD	TCGA;ICGC;COSMIC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P41182	BCL6	P27361	MAPK3	S427	T429I	429	Missense	proximal	2	no	16.223	16.200	EPSD	TCGA;ICGC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P41182	BCL6	P27361	MAPK3	S427	L425I	425	Missense	proximal	-2	no	16.223	15.769	EPSD	TCGA;ICGC;COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P41182	BCL6	P27361	MAPK3	S457	R452M	452	Missense	distal	-5	no	16.788	16.715	EPSD	TCGA;ICGC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P41182	BCL6	P27361	MAPK3	S457	R459H	459	Missense	proximal	2	no	16.788	16.785	EPSD	TCGA;ICGC;COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P41182	BCL6	P27361	MAPK3	S460	R459H	459	Missense	proximal	-1	no	9.365	9.368	EPSD	TCGA;ICGC;COSMIC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P41182	BCL6	P27361	MAPK3	S466	M470I	470	Missense	distal	4	no	16.090	16.127	EPSD	TCGA;ICGC;COSMIC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P41182	BCL6	P27361	MAPK3	S466	R459H	459	Missense	distal	-7	no	16.090	16.079	EPSD	TCGA;ICGC;COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q13164	MAPK7	P27361	MAPK3	S210	P211S	211	Missense	proximal	1	no	12.253	3.200	EPSD	TCGA;ICGC;COSMIC	9.358	Loss
CMGC_MAPK_ERK1_MAPK3_ST	Q13164	MAPK7	P27361	MAPK3	S282	A288D	288	Missense	distal	6	no	16.909	17.258	EPSD	TCGA;ICGC;COSMIC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q13164	MAPK7	P27361	MAPK3	S421	A424S	424	Missense	distal	3	no	15.099	15.142	EPSD	TCGA;ICGC;COSMIC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q13164	MAPK7	P27361	MAPK3	S421	P420S	420	Missense	proximal	-1	no	15.099	15.093	EPSD	TCGA;ICGC;COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q13164	MAPK7	P27361	MAPK3	S433	A430V	430	Missense	distal	-3	no	14.748	14.767	EPSD	TCGA;ICGC;COSMIC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q13164	MAPK7	P27361	MAPK3	T594	P589R	589	Missense	distal	-5	no	13.741	13.701	EPSD	TCGA;ICGC;COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q13164	MAPK7	P27361	MAPK3	S707	V710A	710	Missense	distal	3	no	15.393	15.386	EPSD	TCGA;ICGC;COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q13164	MAPK7	P27361	MAPK3	T733	G738E	738	Missense	distal	5	no	14.651	14.692	PhosphoSitePlus	TCGA;ICGC;COSMIC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q01844	EWSR1	P27361	MAPK3	T79	T79I	79	Missense	central	0	yes	13.962	0.000	PhosphoSitePlus	TCGA;ICGC;COSMIC	9.358	Loss
CMGC_MAPK_ERK1_MAPK3_ST	Q9H9Z2	LIN28A	P27361	MAPK3	T189	P188Q	188	Missense	proximal	-1	no	12.129	12.042	EPSD	TCGA;ICGC;COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q9H9Z2	LIN28A	P27361	MAPK3	T189	G186E	186	Missense	distal	-3	no	12.129	12.142	EPSD	TCGA;ICGC;COSMIC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q12772	SREBF2	P27361	MAPK3	S79	G82R	82	Missense	distal	3	no	9.393	9.387	EPSD	TCGA;ICGC;COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q12772	SREBF2	P27361	MAPK3	S79	S73N	73	Missense	distal	-6	no	9.393	9.271	EPSD	TCGA;ICGC;COSMIC	9.358	Loss
CMGC_MAPK_ERK1_MAPK3_ST	Q12772	SREBF2	P27361	MAPK3	S101	A104V	104	Missense	distal	3	no	16.091	16.097	EPSD	TCGA;ICGC;COSMIC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q12772	SREBF2	P27361	MAPK3	S106	A104V	104	Missense	proximal	-2	no	14.132	14.829	EPSD	TCGA;ICGC;COSMIC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q12772	SREBF2	P27361	MAPK3	S117	P122S	122	Missense	distal	5	no	16.101	16.144	EPSD	TCGA;ICGC;COSMIC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q12772	SREBF2	P27361	MAPK3	S117	P118L	118	Missense	proximal	1	no	16.101	7.063	EPSD	TCGA;ICGC	9.358	Loss
CMGC_MAPK_ERK1_MAPK3_ST	Q12772	SREBF2	P27361	MAPK3	T124	P122S	122	Missense	proximal	-2	no	16.527	15.451	EPSD	TCGA;ICGC;COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q12772	SREBF2	P27361	MAPK3	T124	P118L	118	Missense	distal	-6	no	16.527	16.280	EPSD	TCGA;ICGC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q12772	SREBF2	P27361	MAPK3	T128	R134H	134	Missense	distal	6	no	13.838	13.857	EPSD	TCGA;ICGC;COSMIC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q12772	SREBF2	P27361	MAPK3	T128	P122S	122	Missense	distal	-6	no	13.838	13.922	EPSD	TCGA;ICGC;COSMIC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q12772	SREBF2	P27361	MAPK3	T128	P135L	135	Missense	distal	7	no	13.838	14.030	EPSD	TCGA;ICGC;COSMIC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q12772	SREBF2	P27361	MAPK3	S252	L253F	253	Missense	proximal	1	no	6.835	9.659	EPSD	TCGA;ICGC;COSMIC	9.358	Gain
CMGC_MAPK_ERK1_MAPK3_ST	Q12772	SREBF2	P27361	MAPK3	S432	N427S	427	Missense	distal	-5	no	16.998	17.038	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q12772	SREBF2	P27361	MAPK3	S455	L457V	457	Missense	proximal	2	no	19.584	19.582	PhosphoSitePlus;EPSD	TCGA;ICGC;COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q12772	SREBF2	P27361	MAPK3	S469	A473V	473	Missense	distal	4	no	18.967	19.075	EPSD	TCGA;ICGC;COSMIC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q12772	SREBF2	P27361	MAPK3	S855	M854I	854	Missense	proximal	-1	no	15.976	16.000	EPSD	TCGA;ICGC;COSMIC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q12772	SREBF2	P27361	MAPK3	S914	P915L	915	Missense	proximal	1	no	17.229	8.191	EPSD	TCGA;ICGC;COSMIC	9.358	Loss
CMGC_MAPK_ERK1_MAPK3_ST	Q12772	SREBF2	P27361	MAPK3	S1046	A1045D	1045	Missense	proximal	-1	no	14.561	14.648	EPSD	TCGA;ICGC;COSMIC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q12772	SREBF2	P27361	MAPK3	S1094	R1089H	1089	Missense	distal	-5	no	9.761	9.770	EPSD	TCGA;ICGC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q12772	SREBF2	P27361	MAPK3	S1094	R1089C	1089	Missense	distal	-5	no	9.761	9.644	EPSD	TCGA;ICGC;COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q12772	SREBF2	P27361	MAPK3	S1098	R1102W	1102	Missense	distal	4	no	16.461	15.994	EPSD	TCGA;ICGC;COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P05787	KRT8	P27361	MAPK3	S31	S37F	37	Missense	distal	6	no	10.269	9.556	EPSD	TCGA;ICGC;COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P05787	KRT8	P27361	MAPK3	S36	S37F	37	Missense	proximal	1	no	8.548	11.388	EPSD	TCGA;ICGC;COSMIC	9.358	Gain
CMGC_MAPK_ERK1_MAPK3_ST	P05787	KRT8	P27361	MAPK3	S37	S37F	37	Missense	central	0	yes	11.111	0.000	EPSD	TCGA;ICGC;COSMIC	9.358	Loss
CMGC_MAPK_ERK1_MAPK3_ST	P05787	KRT8	P27361	MAPK3	S432	S438G	438	Missense	distal	6	no	15.714	15.481	PhosphoSitePlus	TCGA;COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P05787	KRT8	P27361	MAPK3	S436	S438G	438	Missense	proximal	2	no	10.523	10.506	EPSD	TCGA;COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P06401	PGR	P27361	MAPK3	S20	S25F	25	Missense	distal	5	no	18.590	18.165	EPSD	TCGA;ICGC;COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P06401	PGR	P27361	MAPK3	S20	S20F	20	Missense	central	0	yes	18.590	0.000	EPSD	TCGA;ICGC;COSMIC	9.358	Loss
CMGC_MAPK_ERK1_MAPK3_ST	P06401	PGR	P27361	MAPK3	S20	L27P	27	Missense	distal	7	no	18.590	18.397	EPSD	TCGA;ICGC;COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P06401	PGR	P27361	MAPK3	S25	S25F	25	Missense	central	0	yes	19.870	0.000	EPSD	TCGA;ICGC;COSMIC	9.358	Loss
CMGC_MAPK_ERK1_MAPK3_ST	P06401	PGR	P27361	MAPK3	S25	S20F	20	Missense	distal	-5	no	19.870	19.736	EPSD	TCGA;ICGC;COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P06401	PGR	P27361	MAPK3	S25	L27P	27	Missense	proximal	2	no	19.870	19.892	EPSD	TCGA;ICGC;COSMIC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P06401	PGR	P27361	MAPK3	S102	G109R	109	Missense	distal	7	no	16.064	16.094	EPSD	TCGA;ICGC;COSMIC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P06401	PGR	P27361	MAPK3	S102	S102I	102	Missense	central	0	yes	16.064	0.000	EPSD	TCGA;ICGC	9.358	Loss
CMGC_MAPK_ERK1_MAPK3_ST	P06401	PGR	P27361	MAPK3	S102	S101C	101	Missense	proximal	-1	no	16.064	15.837	EPSD	TCGA;ICGC;COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P06401	PGR	P27361	MAPK3	S102	S108I	108	Missense	distal	6	no	16.064	15.494	EPSD	TCGA;ICGC;COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P06401	PGR	P27361	MAPK3	S130	P132S	132	Missense	proximal	2	no	15.019	15.021	EPSD	TCGA;ICGC;COSMIC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P06401	PGR	P27361	MAPK3	S190	L197F	197	Missense	distal	7	no	15.067	15.288	EPSD	TCGA;ICGC;COSMIC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P06401	PGR	P27361	MAPK3	S213	A218V	218	Missense	distal	5	no	15.680	15.668	EPSD	TCGA;ICGC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P06401	PGR	P27361	MAPK3	S273	R274H	274	Missense	proximal	1	no	8.252	9.997	EPSD	TCGA;ICGC;COSMIC	9.358	Gain
CMGC_MAPK_ERK1_MAPK3_ST	P06401	PGR	P27361	MAPK3	S294	T299A	299	Missense	distal	5	no	17.200	17.080	PhosphoSitePlus	TCGA;ICGC;COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P06401	PGR	P27361	MAPK3	S294	A287E	287	Missense	distal	-7	no	17.200	17.082	PhosphoSitePlus	TCGA;ICGC;COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P06401	PGR	P27361	MAPK3	S294	R293C	293	Missense	proximal	-1	no	17.200	17.015	PhosphoSitePlus	TCGA;ICGC;COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P06401	PGR	P27361	MAPK3	S328	G332R	332	Missense	distal	4	no	10.883	10.897	EPSD	TCGA;ICGC;COSMIC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P06401	PGR	P27361	MAPK3	S345	F339Y	339	Missense	distal	-6	no	15.926	16.140	EPSD	TCGA;ICGC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P06401	PGR	P27361	MAPK3	T351	A354T	354	Missense	distal	3	no	17.189	17.219	EPSD	TCGA;ICGC;COSMIC;GDSC;CCLE	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P06401	PGR	P27361	MAPK3	S400	A394V	394	Missense	distal	-6	no	13.499	13.486	EPSD	TCGA;ICGC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P06401	PGR	P27361	MAPK3	S554	Q556H	556	Missense	proximal	2	no	17.793	17.800	EPSD	TCGA;ICGC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P06401	PGR	P27361	MAPK3	S554	S552N	552	Missense	proximal	-2	no	17.793	16.849	EPSD	TCGA;ICGC;COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P06401	PGR	P27361	MAPK3	S558	Q556H	556	Missense	proximal	-2	no	10.925	11.461	EPSD	TCGA;ICGC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P06401	PGR	P27361	MAPK3	S558	S552N	552	Missense	distal	-6	no	10.925	10.803	EPSD	TCGA;ICGC;COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P06401	PGR	P27361	MAPK3	S676	Q679E	679	Missense	distal	3	no	17.015	17.024	EPSD	TCGA;ICGC;COSMIC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P06401	PGR	P27361	MAPK3	S676	L683F	683	Missense	distal	7	no	17.015	17.236	EPSD	TCGA;ICGC;COSMIC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P06401	PGR	P27361	MAPK3	S676	R672T	672	Missense	distal	-4	no	17.015	17.034	EPSD	TCGA;ICGC;COSMIC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P06401	PGR	P27361	MAPK3	S676	S676L	676	Missense	central	0	yes	17.015	0.000	EPSD	TCGA;ICGC;COSMIC	9.358	Loss
CMGC_MAPK_ERK1_MAPK3_ST	P06401	PGR	P27361	MAPK3	S676	Q679L	679	Missense	distal	3	no	17.015	17.005	EPSD	TCGA	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P06401	PGR	P27361	MAPK3	S676	R672I	672	Missense	distal	-4	no	17.015	16.933	EPSD	TCGA;ICGC;COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P06401	PGR	P27361	MAPK3	S676	P677T	677	Missense	proximal	1	no	17.015	8.138	EPSD	TCGA;ICGC;COSMIC	9.358	Loss
CMGC_MAPK_ERK1_MAPK3_ST	Q15596	NCOA2	P27361	MAPK3	S29	G27E	27	Missense	proximal	-2	no	17.592	18.063	EPSD	TCGA;ICGC;COSMIC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q15596	NCOA2	P27361	MAPK3	S29	G27R	27	Missense	proximal	-2	no	17.592	18.309	EPSD	TCGA;ICGC;COSMIC;GDSC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q15596	NCOA2	P27361	MAPK3	S29	P23S	23	Missense	distal	-6	no	17.592	17.677	EPSD	TCGA;ICGC;COSMIC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q15596	NCOA2	P27361	MAPK3	T197	R201W	201	Missense	distal	4	no	10.003	9.535	EPSD	TCGA	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q15596	NCOA2	P27361	MAPK3	S267	S266L	266	Missense	proximal	-1	no	9.697	9.609	EPSD	TCGA;ICGC;COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q15596	NCOA2	P27361	MAPK3	S267	L264I	264	Missense	distal	-3	no	9.697	9.662	EPSD	TCGA;ICGC;COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q15596	NCOA2	P27361	MAPK3	S267	S269N	269	Missense	proximal	2	no	9.697	9.680	EPSD	TCGA;ICGC;COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q15596	NCOA2	P27361	MAPK3	S267	R261S	261	Missense	distal	-6	no	9.697	9.858	EPSD	TCGA;ICGC;COSMIC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q15596	NCOA2	P27361	MAPK3	S269	S266L	266	Missense	distal	-3	no	10.984	10.909	EPSD	TCGA;ICGC;COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q15596	NCOA2	P27361	MAPK3	S269	L276F	276	Missense	distal	7	no	10.984	11.205	EPSD	TCGA;ICGC;COSMIC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q15596	NCOA2	P27361	MAPK3	S269	L264I	264	Missense	distal	-5	no	10.984	10.950	EPSD	TCGA;ICGC;COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q15596	NCOA2	P27361	MAPK3	S269	S269N	269	Missense	central	0	yes	10.984	0.000	EPSD	TCGA;ICGC;COSMIC	9.358	Loss
CMGC_MAPK_ERK1_MAPK3_ST	Q15596	NCOA2	P27361	MAPK3	S402	Q406K	406	Missense	distal	4	no	16.657	16.710	EPSD	TCGA;ICGC;COSMIC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q15596	NCOA2	P27361	MAPK3	S402	S399R	399	Missense	distal	-3	no	16.657	16.620	EPSD	TCGA;ICGC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q15596	NCOA2	P27361	MAPK3	S487	R491H	491	Missense	distal	4	no	14.608	14.614	EPSD	TCGA;ICGC;COSMIC;GDSC;CCLE	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q15596	NCOA2	P27361	MAPK3	S493	R491H	491	Missense	proximal	-2	no	15.343	15.515	EPSD	TCGA;ICGC;COSMIC;GDSC;CCLE	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q15596	NCOA2	P27361	MAPK3	S554	K558T	558	Missense	distal	4	no	15.398	15.424	EPSD	TCGA;ICGC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q15596	NCOA2	P27361	MAPK3	S565	S565F	565	Missense	central	0	yes	17.377	0.000	EPSD	TCGA;ICGC;COSMIC	9.358	Loss
CMGC_MAPK_ERK1_MAPK3_ST	Q15596	NCOA2	P27361	MAPK3	S565	M569V	569	Missense	distal	4	no	17.377	17.532	EPSD	TCGA;ICGC;COSMIC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q15596	NCOA2	P27361	MAPK3	S565	P566L	566	Missense	proximal	1	no	17.377	8.339	EPSD	TCGA;ICGC;COSMIC	9.358	Loss
CMGC_MAPK_ERK1_MAPK3_ST	Q15596	NCOA2	P27361	MAPK3	S565	K558T	558	Missense	distal	-7	no	17.377	17.369	EPSD	TCGA;ICGC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q15596	NCOA2	P27361	MAPK3	S655	S655L	655	Missense	central	0	yes	14.809	0.000	EPSD	TCGA;ICGC;COSMIC	9.358	Loss
CMGC_MAPK_ERK1_MAPK3_ST	Q15596	NCOA2	P27361	MAPK3	S655	M652L	652	Missense	distal	-3	no	14.809	14.861	EPSD	TCGA;ICGC;COSMIC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q15596	NCOA2	P27361	MAPK3	S655	P654A	654	Missense	proximal	-1	no	14.809	14.670	EPSD	TCGA;ICGC;COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q15596	NCOA2	P27361	MAPK3	S671	L672F	672	Missense	proximal	1	no	9.373	12.197	EPSD	TCGA;ICGC;COSMIC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q15596	NCOA2	P27361	MAPK3	S671	S668T	668	Missense	distal	-3	no	9.373	9.343	EPSD	TCGA;ICGC;COSMIC	9.358	Loss
CMGC_MAPK_ERK1_MAPK3_ST	Q15596	NCOA2	P27361	MAPK3	S699	D702Y	702	Missense	distal	3	no	15.367	15.348	EPSD	TCGA;ICGC;COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q15596	NCOA2	P27361	MAPK3	S699	S699F	699	Missense	central	0	yes	15.367	0.000	EPSD	TCGA;ICGC	9.358	Loss
CMGC_MAPK_ERK1_MAPK3_ST	Q15596	NCOA2	P27361	MAPK3	S736	T729A	729	Missense	distal	-7	no	18.552	18.625	PhosphoSitePlus	TCGA;ICGC;COSMIC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q15596	NCOA2	P27361	MAPK3	T763	P760T	760	Missense	distal	-3	no	14.607	14.569	EPSD	TCGA;ICGC;COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q15596	NCOA2	P27361	MAPK3	S851	A848T	848	Missense	distal	-3	no	17.368	17.429	EPSD	TCGA;ICGC;COSMIC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q15596	NCOA2	P27361	MAPK3	T854	A848T	848	Missense	distal	-6	no	15.982	16.130	EPSD	TCGA;ICGC;COSMIC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q15596	NCOA2	P27361	MAPK3	S895	T897N	897	Missense	proximal	2	no	18.373	18.367	EPSD	TCGA;ICGC;COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q15596	NCOA2	P27361	MAPK3	S895	A899D	899	Missense	distal	4	no	18.373	18.584	EPSD	TCGA;ICGC;COSMIC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q15596	NCOA2	P27361	MAPK3	S994	T1001M	1001	Missense	distal	7	no	9.916	10.248	EPSD	TCGA;ICGC;COSMIC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q15596	NCOA2	P27361	MAPK3	S994	M990V	990	Missense	distal	-4	no	9.916	9.944	EPSD	TCGA;ICGC;COSMIC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q15596	NCOA2	P27361	MAPK3	S1059	G1057D	1057	Missense	proximal	-2	no	14.165	14.674	EPSD	TCGA;ICGC;COSMIC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q15596	NCOA2	P27361	MAPK3	S1072	P1068L	1068	Missense	distal	-4	no	15.613	15.501	EPSD	TCGA;ICGC;COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q15596	NCOA2	P27361	MAPK3	S1072	A1070S	1070	Missense	proximal	-2	no	15.613	16.888	EPSD	TCGA;ICGC;COSMIC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q15596	NCOA2	P27361	MAPK3	S1072	A1069V	1069	Missense	distal	-3	no	15.613	15.633	EPSD	TCGA;ICGC;COSMIC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q15596	NCOA2	P27361	MAPK3	T1273	M1272T	1272	Missense	proximal	-1	no	12.431	12.557	EPSD	TCGA;ICGC;COSMIC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P36956	SREBF1	P27361	MAPK3	T105	P106A	106	Missense	proximal	1	no	13.759	4.519	EPSD	TCGA;COSMIC	9.358	Loss
CMGC_MAPK_ERK1_MAPK3_ST	P36956	SREBF1	P27361	MAPK3	T105	S98P	98	Missense	distal	-7	no	13.759	13.796	EPSD	TCGA;COSMIC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P36956	SREBF1	P27361	MAPK3	S117	F116S	116	Missense	proximal	-1	no	14.822	15.026	PhosphoSitePlus	TCGA;COSMIC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P36956	SREBF1	P27361	MAPK3	T426	T419I	419	Missense	distal	-7	no	13.292	13.407	EPSD	TCGA;COSMIC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P36956	SREBF1	P27361	MAPK3	T426	V421A	421	Missense	distal	-5	no	13.292	13.269	EPSD	TCGA	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P36956	SREBF1	P27361	MAPK3	S461	P459L	459	Missense	proximal	-2	no	21.242	19.858	EPSD	TCGA	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	O60504	SORBS3	P27361	MAPK3	S28	V35L	35	Missense	distal	7	no	9.957	9.909	EPSD	TCGA;ICGC;COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	O60504	SORBS3	P27361	MAPK3	S29	V35L	35	Missense	distal	6	no	9.439	9.521	EPSD	TCGA;ICGC;COSMIC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	O60504	SORBS3	P27361	MAPK3	S97	I94N	94	Missense	distal	-3	no	9.314	9.381	EPSD	TCGA;ICGC;COSMIC	9.358	Gain
CMGC_MAPK_ERK1_MAPK3_ST	O60504	SORBS3	P27361	MAPK3	T106	T108A	108	Missense	proximal	2	no	9.482	9.455	EPSD	TCGA;ICGC;COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	O60504	SORBS3	P27361	MAPK3	S217	A215S	215	Missense	proximal	-2	no	9.172	10.447	EPSD	TCGA;ICGC	9.358	Gain
CMGC_MAPK_ERK1_MAPK3_ST	O60504	SORBS3	P27361	MAPK3	S339	D345N	345	Missense	distal	6	no	15.206	15.154	EPSD	TCGA;ICGC;COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	O60504	SORBS3	P27361	MAPK3	S339	A335S	335	Missense	distal	-4	no	15.206	15.338	EPSD	TCGA;ICGC;COSMIC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	O60504	SORBS3	P27361	MAPK3	S348	D345N	345	Missense	distal	-3	no	15.273	15.252	EPSD	TCGA;ICGC;COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	O60504	SORBS3	P27361	MAPK3	S348	R353W	353	Missense	distal	5	no	15.273	14.805	EPSD	TCGA;ICGC;COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	O60504	SORBS3	P27361	MAPK3	S373	K380N	380	Missense	distal	7	no	14.892	14.883	EPSD	TCGA;ICGC;COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	O60504	SORBS3	P27361	MAPK3	S508	Y509F	509	Missense	proximal	1	no	10.384	11.219	EPSD	TCGA;ICGC;COSMIC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	O60504	SORBS3	P27361	MAPK3	S508	R501C	501	Missense	distal	-7	no	10.384	10.571	EPSD	TCGA;COSMIC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	O60504	SORBS3	P27361	MAPK3	S530	P531S	531	Missense	proximal	1	no	16.232	7.178	EPSD	TCGA;COSMIC	9.358	Loss
CMGC_MAPK_ERK1_MAPK3_ST	O60504	SORBS3	P27361	MAPK3	S530	G524S	524	Missense	distal	-6	no	16.232	16.294	EPSD	TCGA;COSMIC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	O60504	SORBS3	P27361	MAPK3	S545	P546L	546	Missense	proximal	1	no	18.021	8.983	EPSD	TCGA;ICGC;COSMIC	9.358	Loss
CMGC_MAPK_ERK1_MAPK3_ST	O60504	SORBS3	P27361	MAPK3	S545	R538C	538	Missense	distal	-7	no	18.021	18.208	EPSD	TCGA;COSMIC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	O60504	SORBS3	P27361	MAPK3	S551	P546L	546	Missense	distal	-5	no	16.335	16.280	EPSD	TCGA;ICGC;COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	O60504	SORBS3	P27361	MAPK3	S551	D557N	557	Missense	distal	6	no	16.335	16.282	EPSD	TCGA;ICGC;COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	O60504	SORBS3	P27361	MAPK3	S563	R565C	565	Missense	proximal	2	no	14.694	14.645	EPSD	TCGA;ICGC;COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	O60504	SORBS3	P27361	MAPK3	S563	T567A	567	Missense	distal	4	no	14.694	14.476	EPSD	TCGA;ICGC;COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	O60504	SORBS3	P27361	MAPK3	S563	D557N	557	Missense	distal	-6	no	14.694	14.632	EPSD	TCGA;ICGC;COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	O60504	SORBS3	P27361	MAPK3	S563	R566H	566	Missense	distal	3	no	14.694	14.702	EPSD	TCGA;ICGC;COSMIC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	O60504	SORBS3	P27361	MAPK3	T585	P586S	586	Missense	proximal	1	no	15.686	6.633	EPSD	TCGA;ICGC;COSMIC	9.358	Loss
CMGC_MAPK_ERK1_MAPK3_ST	O60504	SORBS3	P27361	MAPK3	S606	I612M	612	Missense	distal	6	no	16.076	15.996	EPSD	TCGA;ICGC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	O60504	SORBS3	P27361	MAPK3	T615	I612M	612	Missense	distal	-3	no	15.479	15.463	EPSD	TCGA;ICGC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P04150	NR3C1	P27361	MAPK3	T8	P9H	9	Missense	proximal	1	no	15.349	7.594	EPSD	TCGA;COSMIC	9.358	Loss
CMGC_MAPK_ERK1_MAPK3_ST	P04150	NR3C1	P27361	MAPK3	S45	A51T	51	Missense	distal	6	no	14.239	14.610	EPSD	TCGA;ICGC;COSMIC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P04150	NR3C1	P27361	MAPK3	S45	S42Y	42	Missense	distal	-3	no	14.239	14.176	EPSD	TCGA;ICGC;COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P04150	NR3C1	P27361	MAPK3	S211	P212H	212	Missense	proximal	1	no	15.027	7.272	EPSD	TCGA;ICGC;COSMIC	9.358	Loss
CMGC_MAPK_ERK1_MAPK3_ST	P04150	NR3C1	P27361	MAPK3	S226	N222T	222	Missense	distal	-4	no	16.907	16.910	PhosphoSitePlus	TCGA;ICGC;COSMIC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P04150	NR3C1	P27361	MAPK3	S226	A229V	229	Missense	distal	3	no	16.907	16.913	PhosphoSitePlus	TCGA;ICGC;COSMIC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P04150	NR3C1	P27361	MAPK3	S226	G230R	230	Missense	distal	4	no	16.907	16.921	PhosphoSitePlus	TCGA;ICGC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P04150	NR3C1	P27361	MAPK3	S226	I219L	219	Missense	distal	-7	no	16.907	16.860	PhosphoSitePlus	TCGA;ICGC;COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P04150	NR3C1	P27361	MAPK3	T288	P289S	289	Missense	proximal	1	no	14.563	5.510	EPSD	TCGA;ICGC;COSMIC	9.358	Loss
CMGC_MAPK_ERK1_MAPK3_ST	P04150	NR3C1	P27361	MAPK3	S395	S395I	395	Missense	central	0	yes	16.269	0.000	EPSD	TCGA;ICGC	9.358	Loss
CMGC_MAPK_ERK1_MAPK3_ST	P04150	NR3C1	P27361	MAPK3	S404	S404Y	404	Missense	central	0	yes	15.097	0.000	EPSD	TCGA;ICGC	9.358	Loss
CMGC_MAPK_ERK1_MAPK3_ST	P04150	NR3C1	P27361	MAPK3	S408	S404Y	404	Missense	distal	-4	no	11.181	11.078	EPSD	TCGA;ICGC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P04150	NR3C1	P27361	MAPK3	S409	P416Q	416	Missense	distal	7	no	9.342	9.464	EPSD	TCGA;ICGC;COSMIC	9.358	Gain
CMGC_MAPK_ERK1_MAPK3_ST	P04150	NR3C1	P27361	MAPK3	T413	P416Q	416	Missense	distal	3	no	9.451	9.424	EPSD	TCGA;ICGC;COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P43364	MAGEA11	P27361	MAPK3	S13	C12F	12	Missense	proximal	-1	no	16.354	16.377	EPSD	TCGA;ICGC;COSMIC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P43364	MAGEA11	P27361	MAPK3	S13	K20T	20	Missense	distal	7	no	16.354	16.297	EPSD	TCGA;ICGC;COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P43364	MAGEA11	P27361	MAPK3	S13	G8V	8	Missense	distal	-5	no	16.354	16.321	EPSD	TCGA;ICGC;COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P43364	MAGEA11	P27361	MAPK3	S13	K20N	20	Missense	distal	7	no	16.354	16.345	EPSD	TCGA;ICGC;COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P43364	MAGEA11	P27361	MAPK3	S76	R78S	78	Missense	proximal	2	no	15.314	15.327	EPSD	TCGA;ICGC;COSMIC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P43364	MAGEA11	P27361	MAPK3	S76	S76C	76	Missense	central	0	yes	15.314	0.000	EPSD	TCGA;ICGC;COSMIC	9.358	Loss
CMGC_MAPK_ERK1_MAPK3_ST	P43364	MAGEA11	P27361	MAPK3	S76	A70S	70	Missense	distal	-6	no	15.314	15.630	EPSD	TCGA;ICGC;COSMIC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P43364	MAGEA11	P27361	MAPK3	S76	P77L	77	Missense	proximal	1	no	15.314	6.276	EPSD	TCGA;ICGC;COSMIC	9.358	Loss
CMGC_MAPK_ERK1_MAPK3_ST	P43364	MAGEA11	P27361	MAPK3	S76	E73G	73	Missense	distal	-3	no	15.314	15.301	EPSD	TCGA;ICGC;COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P43364	MAGEA11	P27361	MAPK3	S76	A70V	70	Missense	distal	-6	no	15.314	15.301	EPSD	TCGA;ICGC;COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P43364	MAGEA11	P27361	MAPK3	S76	R79I	79	Missense	distal	3	no	15.314	15.285	EPSD	TCGA;ICGC;COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P43364	MAGEA11	P27361	MAPK3	S168	E162K	162	Missense	distal	-6	no	17.154	17.012	EPSD	TCGA;ICGC;COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P43364	MAGEA11	P27361	MAPK3	S174	F180L	180	Missense	distal	6	no	17.385	17.742	PhosphoSitePlus	TCGA;ICGC;COSMIC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P43364	MAGEA11	P27361	MAPK3	S181	F180L	180	Missense	proximal	-1	no	15.962	16.077	EPSD	TCGA;ICGC;COSMIC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P43364	MAGEA11	P27361	MAPK3	S208	G204E	204	Missense	distal	-4	no	15.720	15.735	EPSD	TCGA;ICGC;COSMIC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P43364	MAGEA11	P27361	MAPK3	S208	S208L	208	Missense	central	0	yes	15.720	0.000	EPSD	TCGA;ICGC;COSMIC;GDSC;CCLE	9.358	Loss
CMGC_MAPK_ERK1_MAPK3_ST	P43364	MAGEA11	P27361	MAPK3	S208	E201K	201	Missense	distal	-7	no	15.720	15.772	EPSD	TCGA;ICGC;COSMIC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P43364	MAGEA11	P27361	MAPK3	S208	P205T	205	Missense	distal	-3	no	15.720	15.682	EPSD	TCGA;ICGC;COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P43364	MAGEA11	P27361	MAPK3	S216	H223N	223	Missense	distal	7	no	12.555	12.583	EPSD	TCGA;ICGC;COSMIC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P43364	MAGEA11	P27361	MAPK3	S216	S218F	218	Missense	proximal	2	no	12.555	12.504	EPSD	TCGA;ICGC;COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P35568	IRS1	P27361	MAPK3	S193	V195M	195	Missense	proximal	2	no	13.681	13.663	EPSD	TCGA;ICGC;COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P35568	IRS1	P27361	MAPK3	S312	A314G	314	Missense	proximal	2	no	14.927	14.949	EPSD	TCGA;ICGC;COSMIC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P35568	IRS1	P27361	MAPK3	S323	R327H	327	Missense	distal	4	no	10.232	10.238	EPSD	TCGA;ICGC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P35568	IRS1	P27361	MAPK3	S323	A328T	328	Missense	distal	5	no	10.232	10.351	EPSD	TCGA;ICGC;COSMIC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P35568	IRS1	P27361	MAPK3	S323	S330N	330	Missense	distal	7	no	10.232	10.397	EPSD	TCGA;ICGC;COSMIC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P35568	IRS1	P27361	MAPK3	S323	S323A	323	Missense	central	0	yes	10.232	0.000	EPSD	TCGA;ICGC;COSMIC	9.358	Loss
CMGC_MAPK_ERK1_MAPK3_ST	P35568	IRS1	P27361	MAPK3	S323	P321L	321	Missense	proximal	-2	no	10.232	8.847	EPSD	TCGA;ICGC;COSMIC	9.358	Loss
CMGC_MAPK_ERK1_MAPK3_ST	P35568	IRS1	P27361	MAPK3	S345	R338H	338	Missense	distal	-7	no	17.160	17.149	EPSD	TCGA;ICGC;COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P35568	IRS1	P27361	MAPK3	S345	R338C	338	Missense	distal	-7	no	17.160	17.347	EPSD	TCGA;ICGC;COSMIC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P35568	IRS1	P27361	MAPK3	S345	P346H	346	Missense	proximal	1	no	17.160	9.404	EPSD	TCGA;ICGC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P35568	IRS1	P27361	MAPK3	S348	P346H	346	Missense	proximal	-2	no	17.318	16.091	EPSD	TCGA;ICGC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P35568	IRS1	P27361	MAPK3	S383	P389L	389	Missense	distal	6	no	16.168	15.941	EPSD	TCGA;ICGC;COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P35568	IRS1	P27361	MAPK3	S383	R381H	381	Missense	proximal	-2	no	16.168	16.340	EPSD	TCGA	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P35568	IRS1	P27361	MAPK3	S383	P384H	384	Missense	proximal	1	no	16.168	8.412	EPSD	TCGA;ICGC;COSMIC	9.358	Loss
CMGC_MAPK_ERK1_MAPK3_ST	P35568	IRS1	P27361	MAPK3	S383	P378S	378	Missense	distal	-5	no	16.168	16.173	EPSD	TCGA;ICGC;COSMIC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P35568	IRS1	P27361	MAPK3	S388	P389L	389	Missense	proximal	1	no	13.889	4.851	EPSD	TCGA;ICGC;COSMIC	9.358	Loss
CMGC_MAPK_ERK1_MAPK3_ST	P35568	IRS1	P27361	MAPK3	S388	R381H	381	Missense	distal	-7	no	13.889	13.878	EPSD	TCGA	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P35568	IRS1	P27361	MAPK3	S388	S395C	395	Missense	distal	7	no	13.889	14.501	EPSD	TCGA;ICGC;COSMIC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P35568	IRS1	P27361	MAPK3	S388	P384H	384	Missense	distal	-4	no	13.889	13.854	EPSD	TCGA;ICGC;COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P35568	IRS1	P27361	MAPK3	S419	G424S	424	Missense	distal	5	no	14.960	15.025	EPSD	TCGA;ICGC;COSMIC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P35568	IRS1	P27361	MAPK3	S434	S428L	428	Missense	distal	-6	no	15.936	15.605	EPSD	TCGA;ICGC;COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P35568	IRS1	P27361	MAPK3	S434	F438V	438	Missense	distal	4	no	15.936	16.128	EPSD	TCGA;ICGC;COSMIC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P35568	IRS1	P27361	MAPK3	T446	V445I	445	Missense	proximal	-1	no	15.156	15.109	EPSD	TCGA;ICGC;COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P35568	IRS1	P27361	MAPK3	T446	R443H	443	Missense	distal	-3	no	15.156	15.163	EPSD	TCGA;ICGC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P35568	IRS1	P27361	MAPK3	T495	T498I	498	Missense	distal	3	no	17.120	17.082	EPSD	TCGA;ICGC;COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P35568	IRS1	P27361	MAPK3	T495	G489C	489	Missense	distal	-6	no	17.120	16.623	EPSD	TCGA;ICGC;COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P35568	IRS1	P27361	MAPK3	T495	G488V	488	Missense	distal	-7	no	17.120	17.232	EPSD	TCGA;ICGC;COSMIC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P35568	IRS1	P27361	MAPK3	S503	T498I	498	Missense	distal	-5	no	14.163	14.085	EPSD	TCGA;ICGC;COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P35568	IRS1	P27361	MAPK3	S503	P504A	504	Missense	proximal	1	no	14.163	4.924	EPSD	TCGA;ICGC;COSMIC	9.358	Loss
CMGC_MAPK_ERK1_MAPK3_ST	P35568	IRS1	P27361	MAPK3	S603	H607R	607	Missense	distal	4	no	9.681	9.674	EPSD	TCGA;ICGC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P35568	IRS1	P27361	MAPK3	S603	R600C	600	Missense	distal	-3	no	9.681	9.541	EPSD	TCGA;ICGC;COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P35568	IRS1	P27361	MAPK3	S616	G611C	611	Missense	distal	-5	no	18.082	17.963	PhosphoSitePlus	TCGA;ICGC;COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P35568	IRS1	P27361	MAPK3	S666	S672C	672	Missense	distal	6	no	13.469	12.602	EPSD	TCGA;ICGC;COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P35568	IRS1	P27361	MAPK3	S672	I675V	675	Missense	distal	3	no	15.175	15.189	EPSD	TCGA;ICGC;COSMIC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P35568	IRS1	P27361	MAPK3	S672	G676E	676	Missense	distal	4	no	15.175	15.236	EPSD	TCGA	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P35568	IRS1	P27361	MAPK3	S672	S672C	672	Missense	central	0	yes	15.175	0.000	EPSD	TCGA;ICGC;COSMIC	9.358	Loss
CMGC_MAPK_ERK1_MAPK3_ST	P35568	IRS1	P27361	MAPK3	S736	M733I	733	Missense	distal	-3	no	15.159	15.175	EPSD	TCGA;ICGC;COSMIC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P35568	IRS1	P27361	MAPK3	S736	N742D	742	Missense	distal	6	no	15.159	15.211	EPSD	TCGA;ICGC;COSMIC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P35568	IRS1	P27361	MAPK3	S745	N742D	742	Missense	distal	-3	no	15.265	15.287	EPSD	TCGA;ICGC;COSMIC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P35568	IRS1	P27361	MAPK3	S892	P890S	890	Missense	proximal	-2	no	18.854	17.778	EPSD	TCGA;ICGC;COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P35568	IRS1	P27361	MAPK3	S1000	S1005L	1005	Missense	distal	5	no	10.799	10.528	EPSD	TCGA;ICGC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P35568	IRS1	P27361	MAPK3	S1005	S1005L	1005	Missense	central	0	yes	15.382	0.000	EPSD	TCGA;ICGC	9.358	Loss
CMGC_MAPK_ERK1_MAPK3_ST	P35568	IRS1	P27361	MAPK3	S1011	S1005L	1005	Missense	distal	-6	no	9.596	9.264	EPSD	TCGA;ICGC	9.358	Loss
CMGC_MAPK_ERK1_MAPK3_ST	P35568	IRS1	P27361	MAPK3	S1011	R1016Q	1016	Missense	distal	5	no	9.596	9.594	EPSD	TCGA;ICGC;COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P35568	IRS1	P27361	MAPK3	S1043	P1047S	1047	Missense	distal	4	no	16.583	16.632	EPSD	TCGA;ICGC;COSMIC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P35568	IRS1	P27361	MAPK3	S1078	R1081H	1081	Missense	distal	3	no	14.980	14.987	EPSD	TCGA;ICGC;COSMIC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P35568	IRS1	P27361	MAPK3	T1107	S1109C	1109	Missense	proximal	2	no	14.450	14.388	EPSD	TCGA;ICGC;COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P35568	IRS1	P27361	MAPK3	S1216	S1223G	1223	Missense	distal	7	no	9.348	9.488	EPSD	TCGA;ICGC;COSMIC	9.358	Gain
CMGC_MAPK_ERK1_MAPK3_ST	P35568	IRS1	P27361	MAPK3	S1218	S1223G	1223	Missense	distal	5	no	10.887	10.822	EPSD	TCGA;ICGC;COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P35568	IRS1	P27361	MAPK3	T1219	S1223G	1223	Missense	distal	4	no	10.236	10.075	EPSD	TCGA;ICGC;COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P35568	IRS1	P27361	MAPK3	S1222	S1223G	1223	Missense	proximal	1	no	12.032	9.546	EPSD	TCGA;ICGC;COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P35568	IRS1	P27361	MAPK3	S1223	S1223G	1223	Missense	central	0	yes	11.468	0.000	EPSD	TCGA;ICGC;COSMIC	9.358	Loss
CMGC_MAPK_ERK1_MAPK3_ST	P35568	IRS1	P27361	MAPK3	S1227	S1223G	1223	Missense	distal	-4	no	10.304	10.266	EPSD	TCGA;ICGC;COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P35568	IRS1	P27361	MAPK3	S1227	S1233G	1233	Missense	distal	6	no	10.304	10.072	EPSD	TCGA;ICGC;COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P46527	CDKN1B	P27361	MAPK3	S10	S7C	7	Missense	distal	-3	no	14.456	14.278	EPSD	TCGA;ICGC;COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P46527	CDKN1B	P27361	MAPK3	S10	G9W	9	Missense	proximal	-1	no	14.456	14.242	EPSD	TCGA;ICGC;COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P46527	CDKN1B	P27361	MAPK3	S106	A103V	103	Missense	distal	-3	no	9.902	9.921	EPSD	TCGA;ICGC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q14934	NFATC4	P27361	MAPK3	S819	G824V	824	Missense	distal	5	no	18.092	17.890	EPSD	TCGA;COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P02686	MBP	P27361	MAPK3	S19	T17M	17	Missense	proximal	-2	no	9.539	7.771	EPSD	TCGA;ICGC	9.358	Loss
CMGC_MAPK_ERK1_MAPK3_ST	P02686	MBP	P27361	MAPK3	S19	E25K	25	Missense	distal	6	no	9.539	9.463	EPSD	TCGA;ICGC;COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P02686	MBP	P27361	MAPK3	S26	E25K	25	Missense	proximal	-1	no	9.387	9.357	EPSD	TCGA;ICGC;COSMIC	9.358	Loss
CMGC_MAPK_ERK1_MAPK3_ST	P02686	MBP	P27361	MAPK3	S26	K29N	29	Missense	distal	3	no	9.387	9.390	EPSD	TCGA;ICGC;COSMIC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P02686	MBP	P27361	MAPK3	T106	A99V	99	Missense	distal	-7	no	9.764	9.763	EPSD	TCGA;ICGC;COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q9UPT5	EXOC7	P27361	MAPK3	S130	D128N	128	Missense	proximal	-2	no	16.918	16.505	EPSD	TCGA;ICGC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q9UPT5	EXOC7	P27361	MAPK3	S242	S243Y	243	Missense	proximal	1	no	7.891	9.896	EPSD	TCGA;COSMIC	9.358	Gain
CMGC_MAPK_ERK1_MAPK3_ST	Q9UPT5	EXOC7	P27361	MAPK3	S250	S243Y	243	Missense	distal	-7	no	18.233	18.351	PhosphoSitePlus	TCGA;COSMIC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q9UPT5	EXOC7	P27361	MAPK3	T260	D259Y	259	Missense	proximal	-1	no	14.904	14.874	EPSD	TCGA;ICGC;COSMIC	9.358	Down-regulation
TKL_RIPK_RIPK3_ST	Q9UER7	DAXX	Q9Y572	RIPK3	S110	S110F	110	Missense	central	0	yes	27.214	0.000	EPSD	TCGA;ICGC;COSMIC	23.118	Loss
TKL_RIPK_RIPK3_ST	Q9UER7	DAXX	Q9Y572	RIPK3	S110	E104K	104	Missense	distal	-6	no	27.214	27.371	EPSD	TCGA;ICGC;COSMIC	23.118	Up-regulation
TKL_RIPK_RIPK3_ST	Q9UER7	DAXX	Q9Y572	RIPK3	T162	P155S	155	Missense	distal	-7	no	21.322	23.754	EPSD	TCGA;ICGC;COSMIC	23.118	Gain
TKL_RIPK_RIPK3_ST	Q9UER7	DAXX	Q9Y572	RIPK3	T162	P168S	168	Missense	distal	6	no	21.322	24.527	EPSD	TCGA;ICGC;COSMIC	23.118	Gain
TKL_RIPK_RIPK3_ST	Q9UER7	DAXX	Q9Y572	RIPK3	S165	P168S	168	Missense	distal	3	no	11.861	23.470	EPSD	TCGA;ICGC;COSMIC	23.118	Gain
TKL_RIPK_RIPK3_ST	Q9UER7	DAXX	Q9Y572	RIPK3	T181	S176C	176	Missense	distal	-5	no	25.707	25.115	EPSD	TCGA;ICGC;COSMIC	23.118	Down-regulation
TKL_RIPK_RIPK3_ST	Q9UER7	DAXX	Q9Y572	RIPK3	T181	R180M	180	Missense	proximal	-1	no	25.707	24.969	EPSD	TCGA;ICGC	23.118	Down-regulation
TKL_RIPK_RIPK3_ST	Q9UER7	DAXX	Q9Y572	RIPK3	T181	A175T	175	Missense	distal	-6	no	25.707	25.929	EPSD	TCGA;ICGC	23.118	Up-regulation
TKL_RIPK_RIPK3_ST	Q9UER7	DAXX	Q9Y572	RIPK3	T401	H404Y	404	Missense	distal	3	no	20.657	24.226	EPSD	TCGA;ICGC;COSMIC	23.118	Gain
TKL_RIPK_RIPK3_ST	Q9UER7	DAXX	Q9Y572	RIPK3	T584	S588F	588	Missense	distal	4	no	24.391	25.524	EPSD	TCGA;ICGC;COSMIC;CCLE	23.118	Up-regulation
TKL_RIPK_RIPK3_ST	Q9UER7	DAXX	Q9Y572	RIPK3	T584	S587P	587	Missense	distal	3	no	24.391	12.782	EPSD	TCGA;ICGC;COSMIC	23.118	Loss
TKL_RIPK_RIPK3_ST	Q9UER7	DAXX	Q9Y572	RIPK3	T584	S588Y	588	Missense	distal	4	no	24.391	24.309	EPSD	TCGA;ICGC;COSMIC	23.118	Down-regulation
TKL_RIPK_RIPK3_ST	Q9UER7	DAXX	Q9Y572	RIPK3	T584	S587F	587	Missense	distal	3	no	24.391	20.386	EPSD	TCGA;ICGC;COSMIC	23.118	Loss
TKL_RIPK_RIPK3_ST	Q9UER7	DAXX	Q9Y572	RIPK3	S632	R633W	633	Missense	proximal	1	no	28.632	28.484	EPSD	TCGA;ICGC;COSMIC;GDSC	23.118	Down-regulation
TKL_RIPK_RIPK3_ST	Q9UER7	DAXX	Q9Y572	RIPK3	T639	R633W	633	Missense	distal	-6	no	25.590	25.759	EPSD	TCGA;ICGC;COSMIC;GDSC	23.118	Up-regulation
TKL_RIPK_RIPK3_ST	Q9UER7	DAXX	Q9Y572	RIPK3	T639	G642V	642	Missense	distal	3	no	25.590	22.849	EPSD	TCGA;ICGC;COSMIC	23.118	Loss
TKL_RIPK_RIPK3_ST	Q9UER7	DAXX	Q9Y572	RIPK3	T639	N646S	646	Missense	distal	7	no	25.590	27.747	EPSD	TCGA;ICGC	23.118	Up-regulation
TKL_RIPK_RIPK3_ST	Q9UER7	DAXX	Q9Y572	RIPK3	S668	P667L	667	Missense	proximal	-1	no	51.604	51.431	PhosphoSitePlus	TCGA;ICGC;COSMIC	23.118	Down-regulation
TKL_RIPK_RIPK3_ST	Q9UER7	DAXX	Q9Y572	RIPK3	S668	C664F	664	Missense	distal	-4	no	51.604	51.507	PhosphoSitePlus	TCGA;ICGC;COSMIC	23.118	Down-regulation
TKL_RIPK_RIPK3_ST	Q9UER7	DAXX	Q9Y572	RIPK3	S668	S671F	671	Missense	distal	3	no	51.604	47.599	PhosphoSitePlus	TCGA;ICGC;COSMIC	23.118	Down-regulation
TKL_RIPK_RIPK3_ST	Q9UER7	DAXX	Q9Y572	RIPK3	S668	K662N	662	Missense	distal	-6	no	51.604	51.408	PhosphoSitePlus	TCGA;ICGC;COSMIC	23.118	Down-regulation
TKL_RIPK_RIPK3_ST	Q9UER7	DAXX	Q9Y572	RIPK3	S690	R685M	685	Missense	distal	-5	no	26.081	26.334	EPSD	TCGA;ICGC	23.118	Up-regulation
TKL_RIPK_RIPK3_ST	Q9UER7	DAXX	Q9Y572	RIPK3	T695	P701L	701	Missense	distal	6	no	23.693	26.028	EPSD	TCGA;ICGC;COSMIC	23.118	Up-regulation
TKL_RIPK_RIPK3_ST	Q9UER7	DAXX	Q9Y572	RIPK3	T695	S702F	702	Missense	distal	7	no	23.693	22.265	EPSD	TCGA;ICGC;COSMIC	23.118	Loss
TKL_RIPK_RIPK3_ST	Q9UER7	DAXX	Q9Y572	RIPK3	T709	S702F	702	Missense	distal	-7	no	31.362	30.325	EPSD	TCGA;ICGC;COSMIC	23.118	Down-regulation
TKL_RIPK_RIPK3_ST	Q9UER7	DAXX	Q9Y572	RIPK3	S739	D738H	738	Missense	proximal	-1	no	27.218	26.442	EPSD	TCGA;ICGC;COSMIC	23.118	Down-regulation
TKL_RIPK_RIPK3_ST	Q9UER7	DAXX	Q9Y572	RIPK3	S739	S739F	739	Missense	central	0	yes	27.218	0.000	EPSD	TCGA;ICGC;COSMIC	23.118	Loss
TKL_RIPK_RIPK3_ST	Q9UER7	DAXX	Q9Y572	RIPK3	S739	V735M	735	Missense	distal	-4	no	27.218	27.151	EPSD	TCGA;ICGC;COSMIC	23.118	Down-regulation
TKL_RIPK_RIPK3_ST	Q9Y572	RIPK3	Q9Y572	RIPK3	S199	R196W	196	Missense	distal	-3	no	55.827	56.056	EPSD	TCGA;ICGC;COSMIC	23.118	Up-regulation
TKL_RIPK_RIPK3_ST	Q9Y572	RIPK3	Q9Y572	RIPK3	S199	V204I	204	Missense	distal	5	no	55.827	55.186	EPSD	TCGA;ICGC;COSMIC	23.118	Down-regulation
TKL_RIPK_RIPK3_ST	Q9Y572	RIPK3	Q9Y572	RIPK3	T333	R332I	332	Missense	proximal	-1	no	25.511	24.730	EPSD	TCGA;ICGC	23.118	Down-regulation
TKL_RIPK_RIPK3_ST	Q9Y572	RIPK3	Q9Y572	RIPK3	S339	R332I	332	Missense	distal	-7	no	26.917	27.325	EPSD	TCGA;ICGC	23.118	Up-regulation
TKL_RIPK_RIPK3_ST	Q9Y572	RIPK3	Q9Y572	RIPK3	T416	P409S	409	Missense	distal	-7	no	25.166	27.598	EPSD	TCGA;ICGC;COSMIC	23.118	Up-regulation
TKL_RIPK_RIPK3_ST	Q9Y572	RIPK3	Q9Y572	RIPK3	T416	P411S	411	Missense	distal	-5	no	25.166	26.238	EPSD	TCGA;ICGC;COSMIC	23.118	Up-regulation
TKL_RIPK_RIPK3_ST	Q8NB16	MLKL	Q9Y572	RIPK3	T357	M359L	359	Missense	proximal	2	no	44.609	44.663	PhosphoSitePlus;EPSD	TCGA;ICGC;COSMIC	23.118	Up-regulation
TKL_RIPK_RIPK3_ST	Q8NB16	MLKL	Q9Y572	RIPK3	T357	E351K	351	Missense	distal	-6	no	44.609	44.766	PhosphoSitePlus;EPSD	TCGA;ICGC;COSMIC	23.118	Up-regulation
TKL_RIPK_RIPK3_ST	Q8NB16	MLKL	Q9Y572	RIPK3	T357	Q356H	356	Missense	proximal	-1	no	44.609	44.661	PhosphoSitePlus;EPSD	TCGA;ICGC	23.118	Up-regulation
TKL_RIPK_RIPK3_ST	Q8NB16	MLKL	Q9Y572	RIPK3	S358	M359L	359	Missense	proximal	1	no	47.147	47.432	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	23.118	Up-regulation
TKL_RIPK_RIPK3_ST	Q8NB16	MLKL	Q9Y572	RIPK3	S358	E351K	351	Missense	distal	-7	no	47.147	47.369	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	23.118	Up-regulation
TKL_RIPK_RIPK3_ST	Q8NB16	MLKL	Q9Y572	RIPK3	S358	Q356H	356	Missense	proximal	-2	no	47.147	44.312	EPSD;PhosphoSitePlus	TCGA;ICGC	23.118	Down-regulation
TKL_RIPK_RIPK3_ST	P09622	DLD	Q9Y572	RIPK3	T135	A130E	130	Missense	distal	-5	no	42.289	41.820	PhosphoSitePlus	TCGA;ICGC;COSMIC	23.118	Down-regulation
TKL_RIPK_RIPK3_ST	P09622	DLD	Q9Y572	RIPK3	S208	G205A	205	Missense	distal	-3	no	24.972	26.157	EPSD	TCGA;COSMIC	23.118	Up-regulation
TKL_RIPK_RIPK3_ST	P09622	DLD	Q9Y572	RIPK3	S208	A206V	206	Missense	proximal	-2	no	24.972	22.571	EPSD	TCGA;COSMIC	23.118	Loss
TKL_RIPK_RIPK3_ST	P09622	DLD	Q9Y572	RIPK3	S208	S208F	208	Missense	central	0	yes	24.972	0.000	EPSD	TCGA;COSMIC	23.118	Loss
TKL_RIPK_RIPK3_ST	P09622	DLD	Q9Y572	RIPK3	S208	G205C	205	Missense	distal	-3	no	24.972	25.515	EPSD	TCGA;COSMIC	23.118	Up-regulation
STE_STE20_KHS_MAP4K1_ST	Q16584	MAP3K11	Q92918	MAP4K1	T277	A282V	282	Missense	distal	5	no	2.492	2.563	EPSD	TCGA;ICGC;COSMIC	2.024	Up-regulation
STE_STE20_KHS_MAP4K1_ST	Q16584	MAP3K11	Q92918	MAP4K1	S281	A282V	282	Missense	proximal	1	no	7.980	7.742	PhosphoSitePlus	TCGA;ICGC;COSMIC	2.024	Down-regulation
STE_STE20_KHS_MAP4K1_ST	Q16584	MAP3K11	Q92918	MAP4K1	S419	K413N	413	Missense	distal	-6	no	2.622	2.778	EPSD	TCGA;ICGC;COSMIC	2.024	Up-regulation
STE_STE20_KHS_MAP4K1_ST	Q16584	MAP3K11	Q92918	MAP4K1	T526	P525L	525	Missense	proximal	-1	no	4.012	4.228	EPSD	TCGA;ICGC;COSMIC	2.024	Up-regulation
STE_STE20_KHS_MAP4K1_ST	Q16584	MAP3K11	Q92918	MAP4K1	T526	G520R	520	Missense	distal	-6	no	4.012	3.990	EPSD	TCGA;ICGC;COSMIC	2.024	Down-regulation
STE_STE20_KHS_MAP4K1_ST	Q16584	MAP3K11	Q92918	MAP4K1	T526	R529W	529	Missense	distal	3	no	4.012	4.018	EPSD	TCGA;COSMIC	2.024	Up-regulation
STE_STE20_KHS_MAP4K1_ST	Q16584	MAP3K11	Q92918	MAP4K1	T526	R531Q	531	Missense	distal	5	no	4.012	3.965	EPSD	TCGA;ICGC;COSMIC	2.024	Down-regulation
STE_STE20_KHS_MAP4K1_ST	Q16584	MAP3K11	Q92918	MAP4K1	S693	P687L	687	Missense	distal	-6	no	2.901	2.996	EPSD	TCGA;ICGC;COSMIC	2.024	Up-regulation
STE_STE20_KHS_MAP4K1_ST	Q16584	MAP3K11	Q92918	MAP4K1	S693	T688I	688	Missense	distal	-5	no	2.901	2.754	EPSD	TCGA;COSMIC	2.024	Down-regulation
STE_STE20_KHS_MAP4K1_ST	Q16584	MAP3K11	Q92918	MAP4K1	S746	R747H	747	Missense	proximal	1	no	2.845	2.547	EPSD	TCGA;COSMIC	2.024	Down-regulation
STE_STE20_KHS_MAP4K1_ST	Q16584	MAP3K11	Q92918	MAP4K1	S746	P743L	743	Missense	distal	-3	no	2.845	2.835	EPSD	TCGA;COSMIC	2.024	Down-regulation
STE_STE20_KHS_MAP4K1_ST	Q16584	MAP3K11	Q92918	MAP4K1	S774	R773C	773	Missense	proximal	-1	no	3.104	2.941	EPSD	TCGA;ICGC;COSMIC	2.024	Down-regulation
STE_STE20_KHS_MAP4K1_ST	Q16584	MAP3K11	Q92918	MAP4K1	S774	R768Q	768	Missense	distal	-6	no	3.104	3.501	EPSD	TCGA	2.024	Up-regulation
STE_STE20_KHS_MAP4K1_ST	Q16584	MAP3K11	Q92918	MAP4K1	S774	S770L	770	Missense	distal	-4	no	3.104	2.932	EPSD	TCGA;COSMIC	2.024	Down-regulation
STE_STE20_KHS_MAP4K1_ST	Q16584	MAP3K11	Q92918	MAP4K1	S774	P771L	771	Missense	distal	-3	no	3.104	3.094	EPSD	TCGA;COSMIC	2.024	Down-regulation
STE_STE20_KHS_MAP4K1_ST	Q16584	MAP3K11	Q92918	MAP4K1	S774	P778S	778	Missense	distal	4	no	3.104	3.058	EPSD	TCGA;ICGC;COSMIC	2.024	Down-regulation
STE_STE20_KHS_MAP4K1_ST	Q9BXL7	CARD11	Q92918	MAP4K1	S212	A209T	209	Missense	distal	-3	no	2.422	2.600	EPSD	TCGA;ICGC;COSMIC	2.024	Up-regulation
STE_STE20_KHS_MAP4K1_ST	Q9BXL7	CARD11	Q92918	MAP4K1	S212	K215N	215	Missense	distal	3	no	2.422	2.439	EPSD	TCGA;ICGC;COSMIC	2.024	Up-regulation
STE_STE20_KHS_MAP4K1_ST	Q9BXL7	CARD11	Q92918	MAP4K1	S212	R207C	207	Missense	distal	-5	no	2.422	2.542	EPSD	TCGA;ICGC;COSMIC	2.024	Up-regulation
STE_STE20_KHS_MAP4K1_ST	Q9BXL7	CARD11	Q92918	MAP4K1	S212	K215T	215	Missense	distal	3	no	2.422	2.505	EPSD	TCGA;ICGC;COSMIC	2.024	Up-regulation
STE_STE20_KHS_MAP4K1_ST	Q9BXL7	CARD11	Q92918	MAP4K1	S433	S433R	433	Missense	central	0	yes	2.160	0.000	EPSD	TCGA;ICGC;COSMIC	2.024	Loss
STE_STE20_KHS_MAP4K1_ST	Q9BXL7	CARD11	Q92918	MAP4K1	S433	V429I	429	Missense	distal	-4	no	2.160	2.042	EPSD	TCGA;ICGC;COSMIC	2.024	Down-regulation
STE_STE20_KHS_MAP4K1_ST	Q9BXL7	CARD11	Q92918	MAP4K1	S433	N430S	430	Missense	distal	-3	no	2.160	2.136	EPSD	TCGA;ICGC;COSMIC	2.024	Down-regulation
STE_STE20_KHS_MAP4K1_ST	Q9BXL7	CARD11	Q92918	MAP4K1	T532	G526R	526	Missense	distal	-6	no	2.288	2.266	EPSD	TCGA;ICGC;COSMIC;GDSC;CCLE	2.024	Down-regulation
STE_STE20_KHS_MAP4K1_ST	Q9BXL7	CARD11	Q92918	MAP4K1	T532	P536S	536	Missense	distal	4	no	2.288	2.242	EPSD	TCGA;ICGC;COSMIC	2.024	Down-regulation
STE_STE20_KHS_MAP4K1_ST	Q9BXL7	CARD11	Q92918	MAP4K1	T532	E528K	528	Missense	distal	-4	no	2.288	2.018	EPSD	TCGA;ICGC;COSMIC	2.024	Loss
STE_STE20_KHS_MAP4K1_ST	Q9BXL7	CARD11	Q92918	MAP4K1	T532	G531D	531	Missense	proximal	-1	no	2.288	2.298	EPSD	TCGA;ICGC;COSMIC	2.024	Up-regulation
STE_STE20_KHS_MAP4K1_ST	Q9BXL7	CARD11	Q92918	MAP4K1	T532	G531S	531	Missense	proximal	-1	no	2.288	2.671	EPSD	TCGA;ICGC;COSMIC	2.024	Up-regulation
STE_STE20_KHS_MAP4K1_ST	Q9BXL7	CARD11	Q92918	MAP4K1	T532	E529K	529	Missense	distal	-3	no	2.288	2.378	EPSD	TCGA;ICGC;COSMIC	2.024	Up-regulation
STE_STE20_KHS_MAP4K1_ST	Q9BXL7	CARD11	Q92918	MAP4K1	T532	D533N	533	Missense	proximal	1	no	2.288	2.251	EPSD	TCGA;ICGC;COSMIC	2.024	Down-regulation
STE_STE20_KHS_MAP4K1_ST	Q9BXL7	CARD11	Q92918	MAP4K1	S535	P536S	536	Missense	proximal	1	no	3.463	3.888	EPSD	TCGA;ICGC;COSMIC	2.024	Up-regulation
STE_STE20_KHS_MAP4K1_ST	Q9BXL7	CARD11	Q92918	MAP4K1	S535	E528K	528	Missense	distal	-7	no	3.463	3.499	EPSD	TCGA;ICGC;COSMIC	2.024	Up-regulation
STE_STE20_KHS_MAP4K1_ST	Q9BXL7	CARD11	Q92918	MAP4K1	S535	G531D	531	Missense	distal	-4	no	3.463	3.378	EPSD	TCGA;ICGC;COSMIC	2.024	Down-regulation
STE_STE20_KHS_MAP4K1_ST	Q9BXL7	CARD11	Q92918	MAP4K1	S535	G531S	531	Missense	distal	-4	no	3.463	3.433	EPSD	TCGA;ICGC;COSMIC	2.024	Down-regulation
STE_STE20_KHS_MAP4K1_ST	Q9BXL7	CARD11	Q92918	MAP4K1	S535	E529K	529	Missense	distal	-6	no	3.463	3.474	EPSD	TCGA;ICGC;COSMIC	2.024	Up-regulation
STE_STE20_KHS_MAP4K1_ST	Q9BXL7	CARD11	Q92918	MAP4K1	S535	D533N	533	Missense	proximal	-2	no	3.463	3.661	EPSD	TCGA;ICGC;COSMIC	2.024	Up-regulation
STE_STE20_KHS_MAP4K1_ST	Q9BXL7	CARD11	Q92918	MAP4K1	S538	I544T	544	Missense	distal	6	no	1.604	2.472	EPSD	TCGA;ICGC;COSMIC	2.024	Gain
STE_STE20_KHS_MAP4K1_ST	Q9BXL7	CARD11	Q92918	MAP4K1	S615	R608H	608	Missense	distal	-7	no	2.675	2.746	EPSD	TCGA;ICGC;COSMIC	2.024	Up-regulation
STE_STE20_KHS_MAP4K1_ST	Q9BXL7	CARD11	Q92918	MAP4K1	S615	S614T	614	Missense	proximal	-1	no	2.675	2.290	EPSD	TCGA;ICGC;COSMIC	2.024	Down-regulation
STE_STE20_KHS_MAP4K1_ST	Q9BXL7	CARD11	Q92918	MAP4K1	S615	S621F	621	Missense	distal	6	no	2.675	1.096	EPSD	TCGA;ICGC;COSMIC	2.024	Loss
STE_STE20_KHS_MAP4K1_ST	Q9BXL7	CARD11	Q92918	MAP4K1	S652	S652L	652	Missense	central	0	yes	3.120	0.000	EPSD	TCGA;ICGC;COSMIC;GDSC;CCLE	2.024	Loss
STE_STE20_KHS_MAP4K1_ST	Q9BXL7	CARD11	Q92918	MAP4K1	S652	G657E	657	Missense	distal	5	no	3.120	3.143	EPSD	TCGA;ICGC;COSMIC	2.024	Up-regulation
STE_STE20_KHS_MAP4K1_ST	Q9BXL7	CARD11	Q92918	MAP4K1	T864	G860S	860	Missense	distal	-4	no	2.650	2.620	EPSD	TCGA;ICGC;COSMIC	2.024	Down-regulation
STE_STE20_KHS_MAP4K1_ST	Q9BXL7	CARD11	Q92918	MAP4K1	T880	A877V	877	Missense	distal	-3	no	2.799	2.941	EPSD	TCGA;ICGC;COSMIC	2.024	Up-regulation
STE_STE20_KHS_MAP4K1_ST	Q9BXL7	CARD11	Q92918	MAP4K1	T880	R884W	884	Missense	distal	4	no	2.799	2.516	EPSD	TCGA;ICGC;COSMIC	2.024	Down-regulation
STE_STE20_KHS_MAP4K1_ST	Q9BXL7	CARD11	Q92918	MAP4K1	S923	R918W	918	Missense	distal	-5	no	2.838	2.995	EPSD	TCGA;ICGC;COSMIC	2.024	Up-regulation
STE_STE20_KHS_MAP4K1_ST	Q9BXL7	CARD11	Q92918	MAP4K1	S923	P926L	926	Missense	distal	3	no	2.838	2.765	EPSD	TCGA;ICGC;COSMIC	2.024	Down-regulation
STE_STE20_KHS_MAP4K1_ST	Q9BXL7	CARD11	Q92918	MAP4K1	T1020	R1027Q	1027	Missense	distal	7	no	2.283	2.269	EPSD	TCGA;ICGC;COSMIC	2.024	Down-regulation
STE_STE20_KHS_MAP4K1_ST	Q9BXL7	CARD11	Q92918	MAP4K1	T1020	Q1018R	1018	Missense	proximal	-2	no	2.283	1.982	EPSD	TCGA;ICGC;COSMIC	2.024	Loss
STE_STE20_KHS_MAP4K1_ST	Q9BXL7	CARD11	Q92918	MAP4K1	T1020	T1020M	1020	Missense	central	0	yes	2.283	0.000	EPSD	TCGA;ICGC;COSMIC	2.024	Loss
STE_STE20_KHS_MAP4K1_ST	Q92918	MAP4K1	Q92918	MAP4K1	T165	R169C	169	Missense	distal	4	no	9.210	8.852	PhosphoSitePlus	TCGA;ICGC;COSMIC	2.024	Down-regulation
STE_STE20_KHS_MAP4K1_ST	Q92918	MAP4K1	Q92918	MAP4K1	T165	A164D	164	Missense	proximal	-1	no	9.210	8.771	PhosphoSitePlus	TCGA;ICGC;COSMIC	2.024	Down-regulation
STE_STE20_KHS_MAP4K1_ST	Q92918	MAP4K1	Q92918	MAP4K1	T165	R169H	169	Missense	distal	4	no	9.210	8.890	PhosphoSitePlus	TCGA;ICGC;COSMIC	2.024	Down-regulation
STE_STE20_KHS_MAP4K1_ST	Q92918	MAP4K1	Q92918	MAP4K1	S320	R323H	323	Missense	distal	3	no	2.186	2.180	EPSD	TCGA;ICGC	2.024	Down-regulation
STE_STE20_KHS_MAP4K1_ST	Q92918	MAP4K1	Q92918	MAP4K1	S366	R362Q	362	Missense	distal	-4	no	1.837	2.137	EPSD	TCGA;ICGC;COSMIC	2.024	Gain
STE_STE20_KHS_MAP4K1_ST	Q92918	MAP4K1	Q92918	MAP4K1	S407	E409K	409	Missense	proximal	2	no	2.828	2.732	EPSD	TCGA;ICGC;COSMIC	2.024	Down-regulation
STE_STE20_KHS_MAP4K1_ST	Q92918	MAP4K1	Q92918	MAP4K1	S407	P401S	401	Missense	distal	-6	no	2.828	3.544	EPSD	TCGA;ICGC;COSMIC	2.024	Up-regulation
STE_STE20_KHS_MAP4K1_ST	Q92918	MAP4K1	Q92918	MAP4K1	S407	P411H	411	Missense	distal	4	no	2.828	2.717	EPSD	TCGA;ICGC;COSMIC	2.024	Down-regulation
STE_STE20_KHS_MAP4K1_ST	Q92918	MAP4K1	Q92918	MAP4K1	S407	G412R	412	Missense	distal	5	no	2.828	2.895	EPSD	TCGA;ICGC;COSMIC	2.024	Up-regulation
STE_STE20_KHS_MAP4K1_ST	Q92918	MAP4K1	Q92918	MAP4K1	S430	A429T	429	Missense	proximal	-1	no	2.575	2.123	EPSD	TCGA;ICGC;COSMIC	2.024	Down-regulation
STE_STE20_KHS_MAP4K1_ST	Q92918	MAP4K1	Q92918	MAP4K1	S430	G423R	423	Missense	distal	-7	no	2.575	2.579	EPSD	TCGA;ICGC;COSMIC;CCLE	2.024	Up-regulation
STE_STE20_KHS_MAP4K1_ST	Q92918	MAP4K1	Q92918	MAP4K1	S444	R438H	438	Missense	distal	-6	no	1.914	2.254	EPSD	TCGA;ICGC;COSMIC	2.024	Gain
STE_STE20_KHS_MAP4K1_ST	Q92918	MAP4K1	Q92918	MAP4K1	T445	R438H	438	Missense	distal	-7	no	2.333	2.404	EPSD	TCGA;ICGC;COSMIC	2.024	Up-regulation
STE_STE20_KHS_MAP4K1_ST	Q13094	LCP2	Q92918	MAP4K1	S246	R252S	252	Missense	distal	6	no	2.359	4.298	EPSD	TCGA;ICGC;COSMIC	2.024	Up-regulation
STE_STE20_KHS_MAP4K1_ST	Q13094	LCP2	Q92918	MAP4K1	S246	D244E	244	Missense	proximal	-2	no	2.359	2.514	EPSD	TCGA;ICGC;COSMIC	2.024	Up-regulation
STE_STE20_KHS_MAP4K1_ST	Q13094	LCP2	Q92918	MAP4K1	S246	P242L	242	Missense	distal	-4	no	2.359	1.845	EPSD	TCGA;ICGC	2.024	Loss
STE_STE20_KHS_MAP4K1_ST	Q13094	LCP2	Q92918	MAP4K1	S297	E292D	292	Missense	distal	-5	no	3.146	3.206	EPSD	TCGA;ICGC;COSMIC	2.024	Up-regulation
STE_STE20_KHS_MAP4K1_ST	Q13094	LCP2	Q92918	MAP4K1	S297	R296S	296	Missense	proximal	-1	no	3.146	3.277	EPSD	TCGA;ICGC;COSMIC	2.024	Up-regulation
STE_STE20_KHS_MAP4K1_ST	Q13094	LCP2	Q92918	MAP4K1	S344	P351H	351	Missense	distal	7	no	2.268	2.283	EPSD	TCGA;ICGC;COSMIC	2.024	Up-regulation
STE_STE20_KHS_MAP4K1_ST	Q13094	LCP2	Q92918	MAP4K1	S344	R345K	345	Missense	proximal	1	no	2.268	2.162	EPSD	TCGA;ICGC;COSMIC	2.024	Down-regulation
STE_STE20_KHS_MAP4K1_ST	Q13094	LCP2	Q92918	MAP4K1	S344	M337T	337	Missense	distal	-7	no	2.268	2.248	EPSD	TCGA;ICGC;COSMIC	2.024	Down-regulation
STE_STE20_KHS_MAP4K1_ST	Q13094	LCP2	Q92918	MAP4K1	S344	R345I	345	Missense	proximal	1	no	2.268	2.097	EPSD	TCGA;ICGC;COSMIC	2.024	Down-regulation
STE_STE20_KHS_MAP4K1_ST	Q13094	LCP2	Q92918	MAP4K1	S376	S382C	382	Missense	distal	6	no	9.054	8.124	PhosphoSitePlus	TCGA;ICGC;COSMIC	2.024	Down-regulation
Other_CAMKK_CAMKK-Meta_CAMKK1_ST	Q16566	CAMK4	Q8N5S9	CAMKK1	S12	A11S	11	Missense	proximal	-1	no	2.421	2.436	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	1.176	Up-regulation
Other_CAMKK_CAMKK-Meta_CAMKK1_ST	Q16566	CAMK4	Q8N5S9	CAMKK1	S13	A11S	11	Missense	proximal	-2	no	2.064	2.028	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	1.176	Down-regulation
Other_CAMKK_CAMKK-Meta_CAMKK1_ST	Q16566	CAMK4	Q8N5S9	CAMKK1	S13	S20G	20	Missense	distal	7	no	2.064	2.029	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	1.176	Down-regulation
Other_CAMKK_CAMKK-Meta_CAMKK1_ST	Q16566	CAMK4	Q8N5S9	CAMKK1	T200	G206W	206	Missense	distal	6	no	5.150	5.180	PhosphoSitePlus;EPSD	TCGA;ICGC;COSMIC	1.176	Up-regulation
Other_CAMKK_CAMKK-Meta_CAMKK1_ST	Q16566	CAMK4	Q8N5S9	CAMKK1	T200	G203E	203	Missense	distal	3	no	5.150	5.089	PhosphoSitePlus;EPSD	TCGA;ICGC;COSMIC	1.176	Down-regulation
Other_CAMKK_CAMKK-Meta_CAMKK1_ST	Q16566	CAMK4	Q8N5S9	CAMKK1	T200	M198V	198	Missense	proximal	-2	no	5.150	5.195	PhosphoSitePlus;EPSD	TCGA;ICGC;COSMIC	1.176	Up-regulation
Other_CAMKK_CAMKK-Meta_CAMKK1_ST	Q16566	CAMK4	Q8N5S9	CAMKK1	T204	G206W	206	Missense	proximal	2	no	3.913	3.989	EPSD	TCGA;ICGC;COSMIC	1.176	Up-regulation
Other_CAMKK_CAMKK-Meta_CAMKK1_ST	Q16566	CAMK4	Q8N5S9	CAMKK1	T204	G203E	203	Missense	proximal	-1	no	3.913	3.941	EPSD	TCGA;ICGC;COSMIC	1.176	Up-regulation
Other_CAMKK_CAMKK-Meta_CAMKK1_ST	Q16566	CAMK4	Q8N5S9	CAMKK1	T204	E211K	211	Missense	distal	7	no	3.913	3.884	EPSD	TCGA;ICGC;COSMIC	1.176	Down-regulation
Other_CAMKK_CAMKK-Meta_CAMKK1_ST	Q16566	CAMK4	Q8N5S9	CAMKK1	T204	A209V	209	Missense	distal	5	no	3.913	3.910	EPSD	TCGA;ICGC;COSMIC	1.176	Down-regulation
Other_CAMKK_CAMKK-Meta_CAMKK1_ST	Q16566	CAMK4	Q8N5S9	CAMKK1	T204	M198V	198	Missense	distal	-6	no	3.913	3.927	EPSD	TCGA;ICGC;COSMIC	1.176	Up-regulation
Other_CAMKK_CAMKK-Meta_CAMKK1_ST	Q8TDC3	BRSK1	Q8N5S9	CAMKK1	T189	E188K	188	Missense	proximal	-1	no	4.887	4.872	EPSD	TCGA;COSMIC	1.176	Down-regulation
Other_CAMKK_CAMKK-Meta_CAMKK1_ST	Q8TDC3	BRSK1	Q8N5S9	CAMKK1	T189	G192A	192	Missense	distal	3	no	4.887	4.836	EPSD	TCGA;COSMIC	1.176	Down-regulation
Other_CAMKK_CAMKK-Meta_CAMKK1_ST	Q8TDC3	BRSK1	Q8N5S9	CAMKK1	T406	S404N	404	Missense	proximal	-2	no	1.986	1.965	EPSD	TCGA;COSMIC	1.176	Down-regulation
Other_CAMKK_CAMKK-Meta_CAMKK1_ST	Q8TDC3	BRSK1	Q8N5S9	CAMKK1	T406	L403P	403	Missense	distal	-3	no	1.986	1.679	EPSD	TCGA;COSMIC	1.176	Down-regulation
Other_CAMKK_CAMKK-Meta_CAMKK1_ST	Q8TDC3	BRSK1	Q8N5S9	CAMKK1	T406	D407N	407	Missense	proximal	1	no	1.986	1.967	EPSD	TCGA;COSMIC	1.176	Down-regulation
Other_CAMKK_CAMKK-Meta_CAMKK1_ST	Q8TDC3	BRSK1	Q8N5S9	CAMKK1	T406	G411S	411	Missense	distal	5	no	1.986	1.976	EPSD	TCGA;COSMIC	1.176	Down-regulation
Other_CAMKK_CAMKK-Meta_CAMKK1_ST	Q8IU85	CAMK1D	Q8N5S9	CAMKK1	S179	G175R	175	Missense	distal	-4	no	1.759	1.825	EPSD	TCGA;ICGC;COSMIC	1.176	Up-regulation
Other_CAMKK_CAMKK-Meta_CAMKK1_ST	Q8IU85	CAMK1D	Q8N5S9	CAMKK1	T180	G175R	175	Missense	distal	-5	no	4.531	4.339	PhosphoSitePlus	TCGA;ICGC;COSMIC	1.176	Down-regulation
Other_CAMKK_CAMKK-Meta_CAMKK1_ST	Q8IU85	CAMK1D	Q8N5S9	CAMKK1	S327	G325R	325	Missense	proximal	-2	no	1.519	1.525	EPSD	TCGA;ICGC;COSMIC	1.176	Up-regulation
Other_CAMKK_CAMKK-Meta_CAMKK1_ST	Q8IU85	CAMK1D	Q8N5S9	CAMKK1	S327	S331L	331	Missense	distal	4	no	1.519	1.390	EPSD	TCGA;ICGC;COSMIC	1.176	Down-regulation
Other_CAMKK_CAMKK-Meta_CAMKK1_ST	Q8IU85	CAMK1D	Q8N5S9	CAMKK1	S327	A333V	333	Missense	distal	6	no	1.519	1.529	EPSD	TCGA;ICGC	1.176	Up-regulation
Other_CAMKK_CAMKK-Meta_CAMKK1_ST	Q14012	CAMK1	Q8N5S9	CAMKK1	S176	A178T	178	Missense	proximal	2	no	2.101	1.747	EPSD	TCGA;ICGC	1.176	Down-regulation
Other_CAMKK_CAMKK-Meta_CAMKK1_ST	Q14012	CAMK1	Q8N5S9	CAMKK1	T177	A178T	178	Missense	proximal	1	no	4.909	4.972	PhosphoSitePlus	TCGA;ICGC	1.176	Up-regulation
Other_CAMKK_CAMKK-Meta_CAMKK1_ST	Q14012	CAMK1	Q8N5S9	CAMKK1	T181	A178T	178	Missense	distal	-3	no	2.155	1.844	EPSD	TCGA;ICGC	1.176	Down-regulation
CK1_CK1_CK1-D_CSNK1D_ST	O15055	PER2	P48730	CSNK1D	S56	R51W	51	Missense	distal	-5	no	12.088	8.829	EPSD	TCGA;ICGC;COSMIC	11.915	Loss
CK1_CK1_CK1-D_CSNK1D_ST	O15055	PER2	P48730	CSNK1D	S56	K63N	63	Missense	distal	7	no	12.088	11.965	EPSD	TCGA;ICGC	11.915	Down-regulation
CK1_CK1_CK1-D_CSNK1D_ST	O15055	PER2	P48730	CSNK1D	S56	R51P	51	Missense	distal	-5	no	12.088	12.193	EPSD	TCGA;ICGC;COSMIC	11.915	Up-regulation
CK1_CK1_CK1-D_CSNK1D_ST	O15055	PER2	P48730	CSNK1D	S56	D60N	60	Missense	distal	4	no	12.088	11.387	EPSD	TCGA;ICGC;COSMIC	11.915	Loss
CK1_CK1_CK1-D_CSNK1D_ST	O15055	PER2	P48730	CSNK1D	S82	L83P	83	Missense	proximal	1	no	14.216	14.265	EPSD	TCGA;ICGC;COSMIC	11.915	Up-regulation
CK1_CK1_CK1-D_CSNK1D_ST	O15055	PER2	P48730	CSNK1D	S82	S82R	82	Missense	central	0	yes	14.216	0.000	EPSD	TCGA;ICGC;COSMIC	11.915	Loss
CK1_CK1_CK1-D_CSNK1D_ST	O15055	PER2	P48730	CSNK1D	S82	S82N	82	Missense	central	0	yes	14.216	0.000	EPSD	TCGA;ICGC;COSMIC	11.915	Loss
CK1_CK1_CK1-D_CSNK1D_ST	O15055	PER2	P48730	CSNK1D	S98	S99G	99	Missense	proximal	1	no	10.283	13.443	EPSD	TCGA;ICGC;COSMIC	11.915	Gain
CK1_CK1_CK1-D_CSNK1D_ST	O15055	PER2	P48730	CSNK1D	S771	Q769L	769	Missense	proximal	-2	no	15.052	10.664	EPSD	TCGA;ICGC;COSMIC	11.915	Loss
CK1_CK1_CK1-D_CSNK1D_ST	O15055	PER2	P48730	CSNK1D	S771	P776H	776	Missense	distal	5	no	15.052	13.426	EPSD	TCGA;ICGC;COSMIC	11.915	Down-regulation
CK1_CK1_CK1-D_CSNK1D_ST	O15055	PER2	P48730	CSNK1D	S771	P776L	776	Missense	distal	5	no	15.052	13.931	EPSD	TCGA;ICGC;COSMIC	11.915	Down-regulation
CK1_CK1_CK1-D_CSNK1D_ST	O15055	PER2	P48730	CSNK1D	T774	Q769L	769	Missense	distal	-5	no	12.777	10.471	EPSD	TCGA;ICGC;COSMIC	11.915	Loss
CK1_CK1_CK1-D_CSNK1D_ST	O15055	PER2	P48730	CSNK1D	T774	P776H	776	Missense	proximal	2	no	12.777	12.309	EPSD	TCGA;ICGC;COSMIC	11.915	Down-regulation
CK1_CK1_CK1-D_CSNK1D_ST	O15055	PER2	P48730	CSNK1D	T774	P776L	776	Missense	proximal	2	no	12.777	11.872	EPSD	TCGA;ICGC;COSMIC	11.915	Loss
CK1_CK1_CK1-D_CSNK1D_ST	O15055	PER2	P48730	CSNK1D	S810	V817M	817	Missense	distal	7	no	13.908	14.113	EPSD	TCGA;ICGC;COSMIC;GDSC;CCLE	11.915	Up-regulation
CK1_CK1_CK1-D_CSNK1D_ST	O15055	PER2	P48730	CSNK1D	S810	S813Y	813	Missense	distal	3	no	13.908	10.079	EPSD	TCGA;ICGC	11.915	Loss
CK1_CK1_CK1-D_CSNK1D_ST	O15055	PER2	P48730	CSNK1D	S977	A972S	972	Missense	distal	-5	no	12.031	11.604	EPSD	TCGA;ICGC;COSMIC	11.915	Loss
CK1_CK1_CK1-D_CSNK1D_ST	O15055	PER2	P48730	CSNK1D	S977	R984L	984	Missense	distal	7	no	12.031	13.310	EPSD	TCGA;ICGC;COSMIC	11.915	Up-regulation
CK1_CK1_CK1-D_CSNK1D_ST	O15055	PER2	P48730	CSNK1D	S977	P979T	979	Missense	proximal	2	no	12.031	11.872	EPSD	TCGA;ICGC;COSMIC	11.915	Loss
CK1_CK1_CK1-D_CSNK1D_ST	O15055	PER2	P48730	CSNK1D	S977	P978S	978	Missense	proximal	1	no	12.031	9.712	EPSD	TCGA;ICGC;COSMIC	11.915	Loss
CK1_CK1_CK1-D_CSNK1D_ST	O15055	PER2	P48730	CSNK1D	S977	R984H	984	Missense	distal	7	no	12.031	14.984	EPSD	TCGA;ICGC;COSMIC;GDSC;CCLE	11.915	Up-regulation
CK1_CK1_CK1-D_CSNK1D_ST	O15055	PER2	P48730	CSNK1D	S986	R984L	984	Missense	proximal	-2	no	12.057	9.152	EPSD	TCGA;ICGC;COSMIC	11.915	Loss
CK1_CK1_CK1-D_CSNK1D_ST	O15055	PER2	P48730	CSNK1D	S986	P979T	979	Missense	distal	-7	no	12.057	10.327	EPSD	TCGA;ICGC;COSMIC	11.915	Loss
CK1_CK1_CK1-D_CSNK1D_ST	O15055	PER2	P48730	CSNK1D	S986	R984H	984	Missense	proximal	-2	no	12.057	14.205	EPSD	TCGA;ICGC;COSMIC;GDSC;CCLE	11.915	Up-regulation
CK1_CK1_CK1-D_CSNK1D_ST	O15055	PER2	P48730	CSNK1D	S986	P988S	988	Missense	proximal	2	no	12.057	12.671	EPSD	TCGA;ICGC;COSMIC	11.915	Up-regulation
CK1_CK1_CK1-D_CSNK1D_ST	O15055	PER2	P48730	CSNK1D	S987	R984L	984	Missense	distal	-3	no	13.506	12.489	EPSD	TCGA;ICGC;COSMIC	11.915	Down-regulation
CK1_CK1_CK1-D_CSNK1D_ST	O15055	PER2	P48730	CSNK1D	S987	R984H	984	Missense	distal	-3	no	13.506	12.988	EPSD	TCGA;ICGC;COSMIC;GDSC;CCLE	11.915	Down-regulation
CK1_CK1_CK1-D_CSNK1D_ST	O15055	PER2	P48730	CSNK1D	S987	P988S	988	Missense	proximal	1	no	13.506	11.187	EPSD	TCGA;ICGC;COSMIC	11.915	Loss
CK1_CK1_CK1-D_CSNK1D_ST	O15055	PER2	P48730	CSNK1D	S1236	E1242K	1242	Missense	distal	6	no	12.959	11.160	EPSD	TCGA;ICGC;COSMIC	11.915	Loss
CK1_CK1_CK1-D_CSNK1D_ST	P27707	DCK	P48730	CSNK1D	S11	F12V	12	Missense	proximal	1	no	16.389	18.263	EPSD;PhosphoSitePlus	TCGA	11.915	Up-regulation
CK1_CK1_CK1-D_CSNK1D_ST	P27707	DCK	P48730	CSNK1D	S11	R7K	7	Missense	distal	-4	no	16.389	16.645	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	11.915	Up-regulation
CK1_CK1_CK1-D_CSNK1D_ST	P27707	DCK	P48730	CSNK1D	S11	S8N	8	Missense	distal	-3	no	16.389	14.180	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	11.915	Down-regulation
CK1_CK1_CK1-D_CSNK1D_ST	P27707	DCK	P48730	CSNK1D	S11	R7I	7	Missense	distal	-4	no	16.389	16.876	EPSD;PhosphoSitePlus	TCGA;ICGC	11.915	Up-regulation
CK1_CK1_CK1-D_CSNK1D_ST	P27707	DCK	P48730	CSNK1D	S15	F12V	12	Missense	distal	-3	no	13.354	12.098	EPSD;PhosphoSitePlus	TCGA	11.915	Down-regulation
CK1_CK1_CK1-D_CSNK1D_ST	P27707	DCK	P48730	CSNK1D	S15	S8N	8	Missense	distal	-7	no	13.354	14.091	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	11.915	Up-regulation
CK1_CK1_CK1-D_CSNK1D_ST	P27707	DCK	P48730	CSNK1D	T19	I26M	26	Missense	distal	7	no	16.185	17.544	EPSD	TCGA;ICGC;COSMIC	11.915	Up-regulation
CK1_CK1_CK1-D_CSNK1D_ST	P27707	DCK	P48730	CSNK1D	T19	I26V	26	Missense	distal	7	no	16.185	17.340	EPSD	TCGA;ICGC	11.915	Up-regulation
CK1_CK1_CK1-D_CSNK1D_ST	P27707	DCK	P48730	CSNK1D	T19	F12V	12	Missense	distal	-7	no	16.185	15.665	EPSD	TCGA	11.915	Down-regulation
CK1_CK1_CK1-D_CSNK1D_ST	P27707	DCK	P48730	CSNK1D	T19	K23N	23	Missense	distal	4	no	16.185	15.639	EPSD	TCGA;ICGC	11.915	Down-regulation
CK1_CK1_CK1-D_CSNK1D_ST	P27707	DCK	P48730	CSNK1D	T72	E69K	69	Missense	distal	-3	no	13.371	10.724	PhosphoSitePlus;EPSD	TCGA;ICGC;COSMIC	11.915	Loss
CK1_CK1_CK1-D_CSNK1D_ST	P27707	DCK	P48730	CSNK1D	T72	D66Y	66	Missense	distal	-6	no	13.371	11.780	PhosphoSitePlus;EPSD	TCGA;ICGC	11.915	Loss
CK1_CK1_CK1-D_CSNK1D_ST	P27707	DCK	P48730	CSNK1D	S74	E69K	69	Missense	distal	-5	no	14.916	13.338	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	11.915	Down-regulation
CK1_CK1_CK1-D_CSNK1D_ST	P10636	MAPT	P48730	CSNK1D	S56	P59L	59	Missense	distal	3	no	16.124	17.104	EPSD	TCGA;ICGC;COSMIC	11.915	Up-regulation
CK1_CK1_CK1-D_CSNK1D_ST	P10636	MAPT	P48730	CSNK1D	S56	P59T	59	Missense	distal	3	no	16.124	17.356	EPSD	TCGA;ICGC;COSMIC	11.915	Up-regulation
CK1_CK1_CK1-D_CSNK1D_ST	P10636	MAPT	P48730	CSNK1D	S56	D54E	54	Missense	proximal	-2	no	16.124	16.496	EPSD	TCGA;ICGC;COSMIC	11.915	Up-regulation
CK1_CK1_CK1-D_CSNK1D_ST	P10636	MAPT	P48730	CSNK1D	S56	T52I	52	Missense	distal	-4	no	16.124	16.500	EPSD	TCGA;ICGC;COSMIC	11.915	Up-regulation
CK1_CK1_CK1-D_CSNK1D_ST	P10636	MAPT	P48730	CSNK1D	S56	G60S	60	Missense	distal	4	no	16.124	16.001	EPSD	TCGA;ICGC;COSMIC	11.915	Down-regulation
CK1_CK1_CK1-D_CSNK1D_ST	P10636	MAPT	P48730	CSNK1D	S56	G55R	55	Missense	proximal	-1	no	16.124	15.966	EPSD	TCGA;ICGC;COSMIC	11.915	Down-regulation
CK1_CK1_CK1-D_CSNK1D_ST	P10636	MAPT	P48730	CSNK1D	S64	A66S	66	Missense	proximal	2	no	15.022	14.289	EPSD	TCGA;ICGC;COSMIC	11.915	Down-regulation
CK1_CK1_CK1-D_CSNK1D_ST	P10636	MAPT	P48730	CSNK1D	S64	P59L	59	Missense	distal	-5	no	15.022	13.389	EPSD	TCGA;ICGC;COSMIC	11.915	Down-regulation
CK1_CK1_CK1-D_CSNK1D_ST	P10636	MAPT	P48730	CSNK1D	S64	P59T	59	Missense	distal	-5	no	15.022	13.594	EPSD	TCGA;ICGC;COSMIC	11.915	Down-regulation
CK1_CK1_CK1-D_CSNK1D_ST	P10636	MAPT	P48730	CSNK1D	S64	G60S	60	Missense	distal	-4	no	15.022	15.314	EPSD	TCGA;ICGC;COSMIC	11.915	Up-regulation
CK1_CK1_CK1-D_CSNK1D_ST	P10636	MAPT	P48730	CSNK1D	S68	A72V	72	Missense	distal	4	no	14.093	15.344	EPSD	TCGA;ICGC;COSMIC	11.915	Up-regulation
CK1_CK1_CK1-D_CSNK1D_ST	P10636	MAPT	P48730	CSNK1D	S68	A66S	66	Missense	proximal	-2	no	14.093	12.826	EPSD	TCGA;ICGC;COSMIC	11.915	Down-regulation
CK1_CK1_CK1-D_CSNK1D_ST	P10636	MAPT	P48730	CSNK1D	T71	A77V	77	Missense	distal	6	no	12.010	10.913	EPSD	TCGA;ICGC	11.915	Loss
CK1_CK1_CK1-D_CSNK1D_ST	P10636	MAPT	P48730	CSNK1D	T71	A72V	72	Missense	proximal	1	no	12.010	15.711	EPSD	TCGA;ICGC;COSMIC	11.915	Up-regulation
CK1_CK1_CK1-D_CSNK1D_ST	P10636	MAPT	P48730	CSNK1D	T71	A66S	66	Missense	distal	-5	no	12.010	11.583	EPSD	TCGA;ICGC;COSMIC	11.915	Loss
CK1_CK1_CK1-D_CSNK1D_ST	P10636	MAPT	P48730	CSNK1D	S113	E117K	117	Missense	distal	4	no	16.388	16.856	EPSD	TCGA;ICGC;COSMIC	11.915	Up-regulation
CK1_CK1_CK1-D_CSNK1D_ST	P10636	MAPT	P48730	CSNK1D	S113	A118V	118	Missense	distal	5	no	16.388	15.871	EPSD	TCGA;ICGC;COSMIC	11.915	Down-regulation
CK1_CK1_CK1-D_CSNK1D_ST	P10636	MAPT	P48730	CSNK1D	T123	E117K	117	Missense	distal	-6	no	12.455	11.656	EPSD	TCGA;ICGC;COSMIC	11.915	Loss
CK1_CK1_CK1-D_CSNK1D_ST	P10636	MAPT	P48730	CSNK1D	T123	A118V	118	Missense	distal	-5	no	12.455	12.949	EPSD	TCGA;ICGC;COSMIC	11.915	Up-regulation
CK1_CK1_CK1-D_CSNK1D_ST	P10636	MAPT	P48730	CSNK1D	T167	R168H	168	Missense	proximal	1	no	10.768	12.887	EPSD	TCGA;ICGC;COSMIC	11.915	Gain
CK1_CK1_CK1-D_CSNK1D_ST	P10636	MAPT	P48730	CSNK1D	S171	R168H	168	Missense	distal	-3	no	13.725	13.207	EPSD	TCGA;ICGC;COSMIC	11.915	Down-regulation
CK1_CK1_CK1-D_CSNK1D_ST	P10636	MAPT	P48730	CSNK1D	S171	R168C	168	Missense	distal	-3	no	13.725	13.088	EPSD	TCGA;ICGC;COSMIC	11.915	Down-regulation
CK1_CK1_CK1-D_CSNK1D_ST	P10636	MAPT	P48730	CSNK1D	S228	S232Y	232	Missense	distal	4	no	15.102	15.704	EPSD	TCGA;ICGC;COSMIC	11.915	Up-regulation
CK1_CK1_CK1-D_CSNK1D_ST	P10636	MAPT	P48730	CSNK1D	S228	D223Y	223	Missense	distal	-5	no	15.102	13.912	EPSD	TCGA;ICGC;COSMIC	11.915	Down-regulation
CK1_CK1_CK1-D_CSNK1D_ST	P10636	MAPT	P48730	CSNK1D	S228	S227F	227	Missense	proximal	-1	no	15.102	15.614	EPSD	TCGA;ICGC;COSMIC	11.915	Up-regulation
CK1_CK1_CK1-D_CSNK1D_ST	P10636	MAPT	P48730	CSNK1D	S228	P234L	234	Missense	distal	6	no	15.102	15.708	EPSD	TCGA;ICGC;COSMIC	11.915	Up-regulation
CK1_CK1_CK1-D_CSNK1D_ST	P10636	MAPT	P48730	CSNK1D	S238	S232Y	232	Missense	distal	-6	no	14.130	12.110	EPSD	TCGA;ICGC;COSMIC	11.915	Down-regulation
CK1_CK1_CK1-D_CSNK1D_ST	P10636	MAPT	P48730	CSNK1D	S238	A240T	240	Missense	proximal	2	no	14.130	12.625	EPSD	TCGA;ICGC;COSMIC	11.915	Down-regulation
CK1_CK1_CK1-D_CSNK1D_ST	P10636	MAPT	P48730	CSNK1D	S238	P234L	234	Missense	distal	-4	no	14.130	14.328	EPSD	TCGA;ICGC;COSMIC	11.915	Up-regulation
CK1_CK1_CK1-D_CSNK1D_ST	P10636	MAPT	P48730	CSNK1D	S238	R244Q	244	Missense	distal	6	no	14.130	15.448	EPSD	TCGA;ICGC;COSMIC	11.915	Up-regulation
CK1_CK1_CK1-D_CSNK1D_ST	P10636	MAPT	P48730	CSNK1D	S355	D350G	350	Missense	distal	-5	no	11.733	11.939	EPSD	TCGA;ICGC;COSMIC	11.915	Gain
CK1_CK1_CK1-D_CSNK1D_ST	P10636	MAPT	P48730	CSNK1D	S388	G387R	387	Missense	proximal	-1	no	14.560	14.402	EPSD	TCGA;COSMIC	11.915	Down-regulation
CK1_CK1_CK1-D_CSNK1D_ST	Q99814	EPAS1	P48730	CSNK1D	S148	R144C	144	Missense	distal	-4	no	11.538	11.954	EPSD	TCGA;ICGC;COSMIC;GDSC;CCLE	11.915	Gain
CK1_CK1_CK1-D_CSNK1D_ST	Q99814	EPAS1	P48730	CSNK1D	S148	E145D	145	Missense	distal	-3	no	11.538	12.418	EPSD	TCGA;ICGC;COSMIC	11.915	Gain
CK1_CK1_CK1-D_CSNK1D_ST	Q99814	EPAS1	P48730	CSNK1D	S383	G378C	378	Missense	distal	-5	no	16.536	15.731	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	11.915	Down-regulation
CK1_CK1_CK1-D_CSNK1D_ST	Q99814	EPAS1	P48730	CSNK1D	S383	G380E	380	Missense	distal	-3	no	16.536	16.637	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	11.915	Up-regulation
CK1_CK1_CK1-D_CSNK1D_ST	Q13148	TARDBP	P48730	CSNK1D	S20	S20L	20	Missense	central	0	yes	15.835	0.000	EPSD	TCGA;ICGC;COSMIC	11.915	Loss
CK1_CK1_CK1-D_CSNK1D_ST	Q13148	TARDBP	P48730	CSNK1D	T88	S91L	91	Missense	distal	3	no	13.047	11.259	EPSD	TCGA;ICGC;COSMIC	11.915	Loss
CK1_CK1_CK1-D_CSNK1D_ST	Q13148	TARDBP	P48730	CSNK1D	S92	A99T	99	Missense	distal	7	no	14.725	16.520	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	11.915	Up-regulation
CK1_CK1_CK1-D_CSNK1D_ST	Q13148	TARDBP	P48730	CSNK1D	S92	S91L	91	Missense	proximal	-1	no	14.725	14.840	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	11.915	Up-regulation
CK1_CK1_CK1-D_CSNK1D_ST	Q13148	TARDBP	P48730	CSNK1D	S273	R268I	268	Missense	distal	-5	no	15.148	14.117	EPSD	TCGA;ICGC	11.915	Down-regulation
CK1_CK1_CK1-D_CSNK1D_ST	Q13148	TARDBP	P48730	CSNK1D	S292	G288E	288	Missense	distal	-4	no	13.238	13.426	EPSD;PhosphoSitePlus	TCGA;COSMIC	11.915	Up-regulation
CK1_CK1_CK1-D_CSNK1D_ST	Q13148	TARDBP	P48730	CSNK1D	S292	R293T	293	Missense	proximal	1	no	13.238	13.042	EPSD;PhosphoSitePlus	TCGA;COSMIC	11.915	Down-regulation
CK1_CK1_CK1-D_CSNK1D_ST	Q13148	TARDBP	P48730	CSNK1D	S305	G304S	304	Missense	proximal	-1	no	14.174	14.235	EPSD;PhosphoSitePlus	TCGA;COSMIC	11.915	Up-regulation
CK1_CK1_CK1-D_CSNK1D_ST	Q13148	TARDBP	P48730	CSNK1D	S317	A315V	315	Missense	proximal	-2	no	13.388	10.688	EPSD;PhosphoSitePlus	TCGA;COSMIC	11.915	Loss
CK1_CK1_CK1-D_CSNK1D_ST	Q13148	TARDBP	P48730	CSNK1D	S317	A321G	321	Missense	distal	4	no	13.388	13.681	EPSD;PhosphoSitePlus	TCGA;COSMIC	11.915	Up-regulation
CK1_CK1_CK1-D_CSNK1D_ST	Q13148	TARDBP	P48730	CSNK1D	S389	S393P	393	Missense	distal	4	no	12.633	12.938	EPSD;PhosphoSitePlus	TCGA;COSMIC	11.915	Up-regulation
CK1_CK1_CK1-D_CSNK1D_ST	Q13148	TARDBP	P48730	CSNK1D	S389	S393L	393	Missense	distal	4	no	12.633	12.998	EPSD;PhosphoSitePlus	TCGA;COSMIC	11.915	Up-regulation
CK1_CK1_CK1-D_CSNK1D_ST	Q13148	TARDBP	P48730	CSNK1D	S393	S393P	393	Missense	central	0	yes	18.774	0.000	PhosphoSitePlus;EPSD	TCGA;COSMIC	11.915	Loss
CK1_CK1_CK1-D_CSNK1D_ST	Q13148	TARDBP	P48730	CSNK1D	S393	S393L	393	Missense	central	0	yes	18.774	0.000	PhosphoSitePlus;EPSD	TCGA;COSMIC	11.915	Loss
CK1_CK1_CK1-D_CSNK1D_ST	Q13148	TARDBP	P48730	CSNK1D	S395	S393P	393	Missense	proximal	-2	no	17.157	16.268	EPSD;PhosphoSitePlus	TCGA;COSMIC	11.915	Down-regulation
CK1_CK1_CK1-D_CSNK1D_ST	Q13148	TARDBP	P48730	CSNK1D	S395	S393L	393	Missense	proximal	-2	no	17.157	13.536	EPSD;PhosphoSitePlus	TCGA;COSMIC	11.915	Down-regulation
CK1_CK1_CK1-D_CSNK1D_ST	O14641	DVL2	P48730	CSNK1D	T6	E13D	13	Missense	distal	7	no	11.873	12.259	EPSD	TCGA;ICGC;COSMIC	11.915	Gain
CK1_CK1_CK1-D_CSNK1D_ST	O14641	DVL2	P48730	CSNK1D	T6	G12E	12	Missense	distal	6	no	11.873	13.504	EPSD	TCGA;ICGC;COSMIC	11.915	Gain
CK1_CK1_CK1-D_CSNK1D_ST	O14641	DVL2	P48730	CSNK1D	S126	E123K	123	Missense	distal	-3	no	12.649	10.003	EPSD	TCGA;ICGC;COSMIC	11.915	Loss
CK1_CK1_CK1-D_CSNK1D_ST	O14641	DVL2	P48730	CSNK1D	S155	R161W	161	Missense	distal	6	no	11.853	13.880	EPSD	TCGA;ICGC;COSMIC	11.915	Gain
CK1_CK1_CK1-D_CSNK1D_ST	O14641	DVL2	P48730	CSNK1D	S155	P149L	149	Missense	distal	-6	no	11.853	12.801	EPSD	TCGA;ICGC;COSMIC	11.915	Gain
CK1_CK1_CK1-D_CSNK1D_ST	O14641	DVL2	P48730	CSNK1D	S169	R165H	165	Missense	distal	-4	no	12.854	12.883	EPSD	TCGA;ICGC;COSMIC	11.915	Up-regulation
CK1_CK1_CK1-D_CSNK1D_ST	O14641	DVL2	P48730	CSNK1D	S195	S196C	196	Missense	proximal	1	no	12.326	12.990	EPSD	TCGA;ICGC;COSMIC	11.915	Up-regulation
CK1_CK1_CK1-D_CSNK1D_ST	O14641	DVL2	P48730	CSNK1D	S211	S218I	218	Missense	distal	7	no	13.144	13.372	EPSD	TCGA;ICGC;COSMIC	11.915	Up-regulation
CK1_CK1_CK1-D_CSNK1D_ST	O14641	DVL2	P48730	CSNK1D	S211	D215Y	215	Missense	distal	4	no	13.144	13.350	EPSD	TCGA;ICGC;COSMIC	11.915	Up-regulation
CK1_CK1_CK1-D_CSNK1D_ST	O14641	DVL2	P48730	CSNK1D	T224	R231C	231	Missense	distal	7	no	12.393	10.478	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	11.915	Loss
CK1_CK1_CK1-D_CSNK1D_ST	O14641	DVL2	P48730	CSNK1D	T224	S218I	218	Missense	distal	-6	no	12.393	11.333	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	11.915	Loss
CK1_CK1_CK1-D_CSNK1D_ST	O14641	DVL2	P48730	CSNK1D	S286	N287H	287	Missense	proximal	1	no	13.541	15.679	EPSD	TCGA;ICGC;COSMIC	11.915	Up-regulation
CK1_CK1_CK1-D_CSNK1D_ST	O14641	DVL2	P48730	CSNK1D	S286	R289W	289	Missense	distal	3	no	13.541	15.579	EPSD	TCGA;ICGC;COSMIC;GDSC;CCLE	11.915	Up-regulation
CK1_CK1_CK1-D_CSNK1D_ST	O14641	DVL2	P48730	CSNK1D	S358	P359H	359	Missense	proximal	1	no	15.495	16.635	EPSD	TCGA;ICGC;COSMIC	11.915	Up-regulation
CK1_CK1_CK1-D_CSNK1D_ST	O14641	DVL2	P48730	CSNK1D	S358	Q360H	360	Missense	proximal	2	no	15.495	14.536	EPSD	TCGA;ICGC;COSMIC	11.915	Down-regulation
CK1_CK1_CK1-D_CSNK1D_ST	O14641	DVL2	P48730	CSNK1D	S398	S397F	397	Missense	proximal	-1	no	11.560	12.072	EPSD	TCGA;ICGC	11.915	Gain
CK1_CK1_CK1-D_CSNK1D_ST	O14641	DVL2	P48730	CSNK1D	S398	G395D	395	Missense	distal	-3	no	11.560	12.541	EPSD	TCGA;ICGC;COSMIC	11.915	Gain
CK1_CK1_CK1-D_CSNK1D_ST	O14641	DVL2	P48730	CSNK1D	T403	S397F	397	Missense	distal	-6	no	12.220	11.491	EPSD	TCGA;ICGC	11.915	Loss
CK1_CK1_CK1-D_CSNK1D_ST	O14641	DVL2	P48730	CSNK1D	T403	S398F	398	Missense	distal	-5	no	12.220	11.555	EPSD	TCGA;ICGC;COSMIC	11.915	Loss
CK1_CK1_CK1-D_CSNK1D_ST	O14641	DVL2	P48730	CSNK1D	T403	P409S	409	Missense	distal	6	no	12.220	14.511	EPSD	TCGA;ICGC	11.915	Up-regulation
CK1_CK1_CK1-D_CSNK1D_ST	O14641	DVL2	P48730	CSNK1D	S425	S418P	418	Missense	distal	-7	no	13.355	13.840	EPSD	TCGA;ICGC;COSMIC	11.915	Up-regulation
CK1_CK1_CK1-D_CSNK1D_ST	O14641	DVL2	P48730	CSNK1D	S586	S583N	583	Missense	distal	-3	no	15.874	13.664	EPSD	TCGA;ICGC;COSMIC	11.915	Down-regulation
CK1_CK1_CK1-D_CSNK1D_ST	O14641	DVL2	P48730	CSNK1D	S589	S583N	583	Missense	distal	-6	no	13.242	12.892	EPSD	TCGA;ICGC;COSMIC	11.915	Down-regulation
CK1_CK1_CK1-D_CSNK1D_ST	O14641	DVL2	P48730	CSNK1D	S597	T604M	604	Missense	distal	7	no	14.692	14.024	EPSD	TCGA;ICGC;COSMIC	11.915	Down-regulation
CK1_CK1_CK1-D_CSNK1D_ST	O14641	DVL2	P48730	CSNK1D	S597	R603C	603	Missense	distal	6	no	14.692	12.617	EPSD	TCGA;ICGC;COSMIC	11.915	Down-regulation
CK1_CK1_CK1-D_CSNK1D_ST	O14641	DVL2	P48730	CSNK1D	S616	E613K	613	Missense	distal	-3	no	16.189	13.543	EPSD	TCGA;ICGC;COSMIC	11.915	Down-regulation
CK1_CK1_CK1-D_CSNK1D_ST	O14641	DVL2	P48730	CSNK1D	S616	K615T	615	Missense	proximal	-1	no	16.189	15.579	EPSD	TCGA;ICGC;COSMIC	11.915	Down-regulation
CK1_CK1_CK1-D_CSNK1D_ST	O14641	DVL2	P48730	CSNK1D	S616	E623G	623	Missense	distal	7	no	16.189	16.373	EPSD	TCGA;ICGC	11.915	Up-regulation
CK1_CK1_CK1-D_CSNK1D_ST	O14641	DVL2	P48730	CSNK1D	S618	K615T	615	Missense	distal	-3	no	11.808	13.420	EPSD	TCGA;ICGC;COSMIC	11.915	Gain
CK1_CK1_CK1-D_CSNK1D_ST	O14641	DVL2	P48730	CSNK1D	S618	E623G	623	Missense	distal	5	no	11.808	12.241	EPSD	TCGA;ICGC	11.915	Gain
CK1_CK1_CK1-D_CSNK1D_ST	O14641	DVL2	P48730	CSNK1D	S620	E613K	613	Missense	distal	-7	no	12.404	10.471	EPSD	TCGA;ICGC;COSMIC	11.915	Loss
CK1_CK1_CK1-D_CSNK1D_ST	O14641	DVL2	P48730	CSNK1D	S620	K615T	615	Missense	distal	-5	no	12.404	11.517	EPSD	TCGA;ICGC;COSMIC	11.915	Loss
CK1_CK1_CK1-D_CSNK1D_ST	O14641	DVL2	P48730	CSNK1D	S620	E623G	623	Missense	distal	3	no	12.404	11.960	EPSD	TCGA;ICGC	11.915	Down-regulation
CK1_CK1_CK1-D_CSNK1D_ST	O14641	DVL2	P48730	CSNK1D	S625	R632W	632	Missense	distal	7	no	11.091	13.899	EPSD	TCGA;ICGC;COSMIC	11.915	Gain
CK1_CK1_CK1-D_CSNK1D_ST	O14641	DVL2	P48730	CSNK1D	S638	R632W	632	Missense	distal	-6	no	15.008	13.480	EPSD	TCGA;ICGC;COSMIC	11.915	Down-regulation
CK1_CK1_CK1-D_CSNK1D_ST	Q00987	MDM2	P48730	CSNK1D	S17	T16A	16	Missense	proximal	-1	no	13.405	14.759	EPSD	TCGA;COSMIC	11.915	Up-regulation
CK1_CK1_CK1-D_CSNK1D_ST	Q00987	MDM2	P48730	CSNK1D	S240	S246L	246	Missense	distal	6	no	17.704	16.018	EPSD;PhosphoSitePlus	TCGA;COSMIC	11.915	Down-regulation
CK1_CK1_CK1-D_CSNK1D_ST	Q00987	MDM2	P48730	CSNK1D	S242	S246L	246	Missense	distal	4	no	14.165	14.529	EPSD	TCGA;COSMIC	11.915	Up-regulation
CK1_CK1_CK1-D_CSNK1D_ST	Q00987	MDM2	P48730	CSNK1D	S246	S246L	246	Missense	central	0	yes	21.837	0.000	EPSD	TCGA;COSMIC	11.915	Loss
CK1_CK1_CK1-D_CSNK1D_ST	Q00987	MDM2	P48730	CSNK1D	S253	S246L	246	Missense	distal	-7	no	12.531	10.831	EPSD;PhosphoSitePlus	TCGA;COSMIC	11.915	Loss
CK1_CK1_CK1-D_CSNK1D_ST	P53041	PPP5C	P48730	CSNK1D	T362	R367Q	367	Missense	distal	5	no	13.346	12.711	PhosphoSitePlus	TCGA;ICGC;COSMIC;GDSC;CCLE	11.915	Down-regulation
CK1_CK1_CK1-D_CSNK1D_ST	P53041	PPP5C	P48730	CSNK1D	T362	G360S	360	Missense	proximal	-2	no	13.346	12.743	PhosphoSitePlus	TCGA;ICGC	11.915	Down-regulation
CK1_CK1_CK1-D_CSNK1D_ST	P56817	BACE1	P48730	CSNK1D	T47	P44S	44	Missense	distal	-3	no	9.046	13.046	EPSD	TCGA;ICGC;COSMIC	11.915	Gain
CK1_CK1_CK1-D_CSNK1D_ST	P56817	BACE1	P48730	CSNK1D	S71	V77M	77	Missense	distal	6	no	11.760	15.383	EPSD	TCGA;ICGC;COSMIC	11.915	Gain
CK1_CK1_CK1-D_CSNK1D_ST	P12830	CDH1	P48730	CSNK1D	S770	L776M	776	Missense	distal	6	no	10.013	12.583	EPSD	TCGA;COSMIC	11.915	Gain
CK1_CK1_CK1-D_CSNK1D_ST	P12830	CDH1	P48730	CSNK1D	S838	E841K	841	Missense	distal	3	no	13.691	12.802	EPSD	TCGA;COSMIC	11.915	Down-regulation
CK1_CK1_CK1-D_CSNK1D_ST	P12830	CDH1	P48730	CSNK1D	S840	E841K	841	Missense	proximal	1	no	15.917	12.536	EPSD	TCGA;COSMIC	11.915	Down-regulation
CK1_CK1_CK1-D_CSNK1D_ST	P12830	CDH1	P48730	CSNK1D	S844	S850F	850	Missense	distal	6	no	22.190	21.643	PhosphoSitePlus	TCGA;COSMIC	11.915	Down-regulation
CK1_CK1_CK1-D_CSNK1D_ST	P12830	CDH1	P48730	CSNK1D	S844	E841K	841	Missense	distal	-3	no	22.190	19.544	PhosphoSitePlus	TCGA;COSMIC	11.915	Down-regulation
CK1_CK1_CK1-D_CSNK1D_ST	P25054	APC	P48730	CSNK1D	S5	A2D	2	Missense	distal	-3	no	12.628	15.396	EPSD	TCGA;COSMIC	11.915	Up-regulation
CK1_CK1_CK1-D_CSNK1D_ST	P25054	APC	P48730	CSNK1D	S5	A3T	3	Missense	proximal	-2	no	12.628	12.970	EPSD	TCGA;ICGC;COSMIC	11.915	Up-regulation
CK1_CK1_CK1-D_CSNK1D_ST	P25054	APC	P48730	CSNK1D	S102	G108A	108	Missense	distal	6	no	12.883	12.713	EPSD	TCGA;ICGC;COSMIC	11.915	Down-regulation
CK1_CK1_CK1-D_CSNK1D_ST	P25054	APC	P48730	CSNK1D	S102	E109A	109	Missense	distal	7	no	12.883	12.660	EPSD	TCGA;ICGC;COSMIC	11.915	Down-regulation
CK1_CK1_CK1-D_CSNK1D_ST	P25054	APC	P48730	CSNK1D	S111	G108A	108	Missense	distal	-3	no	17.073	15.287	EPSD	TCGA;ICGC;COSMIC	11.915	Down-regulation
CK1_CK1_CK1-D_CSNK1D_ST	P25054	APC	P48730	CSNK1D	S111	E109A	109	Missense	proximal	-2	no	17.073	17.258	EPSD	TCGA;ICGC;COSMIC	11.915	Up-regulation
CK1_CK1_CK1-D_CSNK1D_ST	P25054	APC	P48730	CSNK1D	S705	A703E	703	Missense	proximal	-2	no	12.044	11.860	EPSD	TCGA;ICGC;COSMIC	11.915	Loss
CK1_CK1_CK1-D_CSNK1D_ST	P25054	APC	P48730	CSNK1D	S780	D777G	777	Missense	distal	-3	no	12.201	11.220	EPSD	TCGA;ICGC;COSMIC	11.915	Loss
CK1_CK1_CK1-D_CSNK1D_ST	P25054	APC	P48730	CSNK1D	S780	R786H	786	Missense	distal	6	no	12.201	13.459	EPSD	TCGA;ICGC;COSMIC	11.915	Up-regulation
CK1_CK1_CK1-D_CSNK1D_ST	P25054	APC	P48730	CSNK1D	S780	N778S	778	Missense	proximal	-2	no	12.201	13.823	EPSD	TCGA;ICGC;COSMIC	11.915	Up-regulation
CK1_CK1_CK1-D_CSNK1D_ST	P25054	APC	P48730	CSNK1D	S905	S905R	905	Missense	central	0	yes	12.169	0.000	EPSD	TCGA	11.915	Loss
CK1_CK1_CK1-D_CSNK1D_ST	P25054	APC	P48730	CSNK1D	S905	S906Y	906	Missense	proximal	1	no	12.169	12.277	EPSD	TCGA;ICGC;COSMIC	11.915	Up-regulation
CK1_CK1_CK1-D_CSNK1D_ST	P25054	APC	P48730	CSNK1D	S987	P981S	981	Missense	distal	-6	no	11.866	13.509	EPSD	TCGA;ICGC;COSMIC	11.915	Gain
CK1_CK1_CK1-D_CSNK1D_ST	P25054	APC	P48730	CSNK1D	S1032	L1029I	1029	Missense	distal	-3	no	15.228	9.362	EPSD	TCGA;ICGC;COSMIC	11.915	Loss
CK1_CK1_CK1-D_CSNK1D_ST	P25054	APC	P48730	CSNK1D	S1032	L1036W	1036	Missense	distal	4	no	15.228	15.570	EPSD	TCGA;ICGC;COSMIC	11.915	Up-regulation
CK1_CK1_CK1-D_CSNK1D_ST	P25054	APC	P48730	CSNK1D	S1032	L1036F	1036	Missense	distal	4	no	15.228	15.287	EPSD	TCGA;ICGC;COSMIC	11.915	Up-regulation
CK1_CK1_CK1-D_CSNK1D_ST	P25054	APC	P48730	CSNK1D	S1032	Y1027H	1027	Missense	distal	-5	no	15.228	14.447	EPSD	TCGA;ICGC;COSMIC	11.915	Down-regulation
CK1_CK1_CK1-D_CSNK1D_ST	P25054	APC	P48730	CSNK1D	S1081	D1083H	1083	Missense	proximal	2	no	12.862	11.408	EPSD	TCGA;ICGC;COSMIC	11.915	Loss
CK1_CK1_CK1-D_CSNK1D_ST	P25054	APC	P48730	CSNK1D	S1081	K1088T	1088	Missense	distal	7	no	12.862	14.192	EPSD	TCGA;ICGC;COSMIC	11.915	Up-regulation
CK1_CK1_CK1-D_CSNK1D_ST	P25054	APC	P48730	CSNK1D	S1081	V1077D	1077	Missense	distal	-4	no	12.862	13.085	EPSD	TCGA;ICGC;COSMIC	11.915	Up-regulation
CK1_CK1_CK1-D_CSNK1D_ST	P25054	APC	P48730	CSNK1D	S1128	N1124I	1124	Missense	distal	-4	no	14.298	14.526	EPSD	TCGA;ICGC;COSMIC	11.915	Up-regulation
CK1_CK1_CK1-D_CSNK1D_ST	P25054	APC	P48730	CSNK1D	S1128	N1122D	1122	Missense	distal	-6	no	14.298	14.219	EPSD	TCGA;ICGC;COSMIC	11.915	Down-regulation
CK1_CK1_CK1-D_CSNK1D_ST	P25054	APC	P48730	CSNK1D	T1220	T1218M	1218	Missense	proximal	-2	no	12.367	9.121	EPSD	TCGA;ICGC;COSMIC	11.915	Loss
CK1_CK1_CK1-D_CSNK1D_ST	P25054	APC	P48730	CSNK1D	T1220	S1215I	1215	Missense	distal	-5	no	12.367	11.224	EPSD	TCGA;ICGC;COSMIC	11.915	Loss
CK1_CK1_CK1-D_CSNK1D_ST	P25054	APC	P48730	CSNK1D	T1220	S1219F	1219	Missense	proximal	-1	no	12.367	12.879	EPSD	TCGA;ICGC	11.915	Up-regulation
CK1_CK1_CK1-D_CSNK1D_ST	P25054	APC	P48730	CSNK1D	S1222	T1218M	1218	Missense	distal	-4	no	15.401	15.512	EPSD	TCGA;ICGC;COSMIC	11.915	Up-regulation
CK1_CK1_CK1-D_CSNK1D_ST	P25054	APC	P48730	CSNK1D	S1222	S1215I	1215	Missense	distal	-7	no	15.401	15.095	EPSD	TCGA;ICGC;COSMIC	11.915	Down-regulation
CK1_CK1_CK1-D_CSNK1D_ST	P25054	APC	P48730	CSNK1D	S1222	S1219F	1219	Missense	distal	-3	no	15.401	13.314	EPSD	TCGA;ICGC	11.915	Down-regulation
CK1_CK1_CK1-D_CSNK1D_ST	P25054	APC	P48730	CSNK1D	T1301	E1295K	1295	Missense	distal	-6	no	12.823	12.024	EPSD	TCGA;ICGC;COSMIC	11.915	Down-regulation
CK1_CK1_CK1-D_CSNK1D_ST	P25054	APC	P48730	CSNK1D	T1301	D1297G	1297	Missense	distal	-4	no	12.823	12.775	EPSD	TCGA;ICGC;COSMIC	11.915	Down-regulation
CK1_CK1_CK1-D_CSNK1D_ST	P25054	APC	P48730	CSNK1D	T1301	S1298Y	1298	Missense	distal	-3	no	12.823	11.552	EPSD	TCGA;ICGC;COSMIC	11.915	Loss
CK1_CK1_CK1-D_CSNK1D_ST	P25054	APC	P48730	CSNK1D	S1343	S1343C	1343	Missense	central	0	yes	11.943	0.000	EPSD	TCGA;ICGC;COSMIC	11.915	Loss
CK1_CK1_CK1-D_CSNK1D_ST	P25054	APC	P48730	CSNK1D	S1364	P1361S	1361	Missense	distal	-3	no	9.160	13.159	EPSD	TCGA;ICGC;COSMIC	11.915	Gain
CK1_CK1_CK1-D_CSNK1D_ST	P25054	APC	P48730	CSNK1D	T1368	Q1367E	1367	Missense	proximal	-1	no	14.760	15.545	EPSD	TCGA;ICGC;COSMIC	11.915	Up-regulation
CK1_CK1_CK1-D_CSNK1D_ST	P25054	APC	P48730	CSNK1D	T1368	P1361S	1361	Missense	distal	-7	no	14.760	14.275	EPSD	TCGA;ICGC;COSMIC	11.915	Down-regulation
CK1_CK1_CK1-D_CSNK1D_ST	P25054	APC	P48730	CSNK1D	S1505	A1508D	1508	Missense	distal	3	no	14.387	13.909	EPSD;PhosphoSitePlus	TCGA;ICGC	11.915	Down-regulation
CK1_CK1_CK1-D_CSNK1D_ST	P25054	APC	P48730	CSNK1D	S1539	E1544Q	1544	Missense	distal	5	no	13.822	13.359	EPSD	TCGA;ICGC;COSMIC	11.915	Down-regulation
CK1_CK1_CK1-D_CSNK1D_ST	P25054	APC	P48730	CSNK1D	S1539	E1540G	1540	Missense	proximal	1	no	13.822	14.436	EPSD	TCGA;ICGC;COSMIC	11.915	Up-regulation
CK1_CK1_CK1-D_CSNK1D_ST	P25054	APC	P48730	CSNK1D	S1539	S1539L	1539	Missense	central	0	yes	13.822	0.000	EPSD	TCGA;ICGC;COSMIC	11.915	Loss
CK1_CK1_CK1-D_CSNK1D_ST	P25054	APC	P48730	CSNK1D	T1556	I1557V	1557	Missense	proximal	1	no	12.380	15.078	EPSD	TCGA;ICGC;COSMIC	11.915	Up-regulation
CK1_CK1_CK1-D_CSNK1D_ST	P25054	APC	P48730	CSNK1D	T1556	D1562N	1562	Missense	distal	6	no	12.380	12.820	EPSD	TCGA;ICGC;COSMIC	11.915	Up-regulation
CK1_CK1_CK1-D_CSNK1D_ST	P25054	APC	P48730	CSNK1D	T1556	A1553V	1553	Missense	distal	-3	no	12.380	11.573	EPSD	TCGA;ICGC;COSMIC	11.915	Loss
CK1_CK1_CK1-D_CSNK1D_ST	P25054	APC	P48730	CSNK1D	T1556	L1563I	1563	Missense	distal	7	no	12.380	10.802	EPSD	TCGA;ICGC;COSMIC	11.915	Loss
CK1_CK1_CK1-D_CSNK1D_ST	P25054	APC	P48730	CSNK1D	S1567	D1562N	1562	Missense	distal	-5	no	11.221	12.908	EPSD	TCGA;ICGC;COSMIC	11.915	Gain
CK1_CK1_CK1-D_CSNK1D_ST	P25054	APC	P48730	CSNK1D	S1754	A1755V	1755	Missense	proximal	1	no	10.956	14.657	EPSD	TCGA;ICGC;COSMIC	11.915	Gain
CK1_CK1_CK1-D_CSNK1D_ST	P25054	APC	P48730	CSNK1D	S1757	S1758F	1758	Missense	proximal	1	no	12.417	13.808	EPSD	TCGA;ICGC;COSMIC	11.915	Up-regulation
CK1_CK1_CK1-D_CSNK1D_ST	P25054	APC	P48730	CSNK1D	S1757	S1757Y	1757	Missense	central	0	yes	12.417	0.000	EPSD	TCGA;ICGC	11.915	Loss
CK1_CK1_CK1-D_CSNK1D_ST	P25054	APC	P48730	CSNK1D	S1757	A1755V	1755	Missense	proximal	-2	no	12.417	9.717	EPSD	TCGA;ICGC;COSMIC	11.915	Loss
CK1_CK1_CK1-D_CSNK1D_ST	P25054	APC	P48730	CSNK1D	S1861	S1861Y	1861	Missense	central	0	yes	12.600	0.000	EPSD	TCGA;ICGC;COSMIC	11.915	Loss
CK1_CK1_CK1-D_CSNK1D_ST	P25054	APC	P48730	CSNK1D	S1863	S1861Y	1861	Missense	proximal	-2	no	12.254	8.532	EPSD	TCGA;ICGC;COSMIC	11.915	Loss
CK1_CK1_CK1-D_CSNK1D_ST	P25054	APC	P48730	CSNK1D	S1864	S1861Y	1861	Missense	distal	-3	no	12.673	11.401	EPSD	TCGA;ICGC;COSMIC	11.915	Loss
CK1_CK1_CK1-D_CSNK1D_ST	P25054	APC	P48730	CSNK1D	S1896	E1891Q	1891	Missense	distal	-5	no	12.520	12.156	EPSD	TCGA;ICGC;COSMIC	11.915	Down-regulation
CK1_CK1_CK1-D_CSNK1D_ST	P25054	APC	P48730	CSNK1D	S1896	A1892V	1892	Missense	distal	-4	no	12.520	11.753	EPSD	TCGA;ICGC;COSMIC	11.915	Loss
CK1_CK1_CK1-D_CSNK1D_ST	P25054	APC	P48730	CSNK1D	S2034	D2033G	2033	Missense	proximal	-1	no	12.704	12.307	EPSD	TCGA;ICGC;COSMIC	11.915	Down-regulation
CK1_CK1_CK1-D_CSNK1D_ST	P25054	APC	P48730	CSNK1D	S2034	S2029Y	2029	Missense	distal	-5	no	12.704	11.524	EPSD	TCGA;ICGC;COSMIC	11.915	Loss
CK1_CK1_CK1-D_CSNK1D_ST	P25054	APC	P48730	CSNK1D	S2034	S2029F	2029	Missense	distal	-5	no	12.704	12.040	EPSD	TCGA;ICGC;COSMIC	11.915	Down-regulation
CK1_CK1_CK1-D_CSNK1D_ST	P25054	APC	P48730	CSNK1D	S2110	G2107S	2107	Missense	distal	-3	no	11.746	12.495	EPSD	TCGA;ICGC;COSMIC	11.915	Gain
CK1_CK1_CK1-D_CSNK1D_ST	P25054	APC	P48730	CSNK1D	S2242	P2245H	2245	Missense	distal	3	no	11.010	12.616	EPSD	TCGA;ICGC	11.915	Gain
CK1_CK1_CK1-D_CSNK1D_ST	P25054	APC	P48730	CSNK1D	S2244	T2243A	2243	Missense	proximal	-1	no	13.176	14.530	EPSD	TCGA;ICGC	11.915	Up-regulation
CK1_CK1_CK1-D_CSNK1D_ST	P25054	APC	P48730	CSNK1D	S2244	G2250V	2250	Missense	distal	6	no	13.176	11.909	EPSD	TCGA;ICGC;COSMIC	11.915	Loss
CK1_CK1_CK1-D_CSNK1D_ST	P25054	APC	P48730	CSNK1D	S2244	S2242N	2242	Missense	proximal	-2	no	13.176	11.553	EPSD	TCGA;ICGC;COSMIC	11.915	Loss
CK1_CK1_CK1-D_CSNK1D_ST	P25054	APC	P48730	CSNK1D	S2244	S2242I	2242	Missense	proximal	-2	no	13.176	9.139	EPSD	TCGA;ICGC	11.915	Loss
CK1_CK1_CK1-D_CSNK1D_ST	P25054	APC	P48730	CSNK1D	S2244	P2245H	2245	Missense	proximal	1	no	13.176	14.316	EPSD	TCGA;ICGC	11.915	Up-regulation
CK1_CK1_CK1-D_CSNK1D_ST	P25054	APC	P48730	CSNK1D	S2290	G2293V	2293	Missense	distal	3	no	12.000	9.422	EPSD	TCGA;ICGC;COSMIC	11.915	Loss
CK1_CK1_CK1-D_CSNK1D_ST	P25054	APC	P48730	CSNK1D	S2307	S2307L	2307	Missense	central	0	yes	12.844	0.000	EPSD	TCGA;ICGC;COSMIC;CCLE	11.915	Loss
CK1_CK1_CK1-D_CSNK1D_ST	P25054	APC	P48730	CSNK1D	S2307	S2300C	2300	Missense	distal	-7	no	12.844	11.799	EPSD	TCGA;ICGC;COSMIC	11.915	Loss
CK1_CK1_CK1-D_CSNK1D_ST	P25054	APC	P48730	CSNK1D	S2307	A2313S	2313	Missense	distal	6	no	12.844	14.484	EPSD	TCGA;ICGC;COSMIC	11.915	Up-regulation
CK1_CK1_CK1-D_CSNK1D_ST	P25054	APC	P48730	CSNK1D	S2307	S2300Y	2300	Missense	distal	-7	no	12.844	10.412	EPSD	TCGA	11.915	Loss
CK1_CK1_CK1-D_CSNK1D_ST	P25054	APC	P48730	CSNK1D	S2310	S2307L	2307	Missense	distal	-3	no	13.717	11.512	EPSD	TCGA;ICGC;COSMIC;CCLE	11.915	Loss
CK1_CK1_CK1-D_CSNK1D_ST	P25054	APC	P48730	CSNK1D	S2310	A2313S	2313	Missense	distal	3	no	13.717	14.038	EPSD	TCGA;ICGC;COSMIC	11.915	Up-regulation
CK1_CK1_CK1-D_CSNK1D_ST	P25054	APC	P48730	CSNK1D	S2359	G2360S	2360	Missense	proximal	1	no	14.602	11.442	EPSD	TCGA;ICGC;COSMIC	11.915	Loss
CK1_CK1_CK1-D_CSNK1D_ST	P25054	APC	P48730	CSNK1D	S2427	S2429F	2429	Missense	proximal	2	no	12.268	11.593	EPSD	TCGA;COSMIC	11.915	Loss
CK1_CK1_CK1-D_CSNK1D_ST	P25054	APC	P48730	CSNK1D	S2427	D2430H	2430	Missense	distal	3	no	12.268	11.905	EPSD	TCGA;ICGC;COSMIC	11.915	Loss
CK1_CK1_CK1-D_CSNK1D_ST	P25054	APC	P48730	CSNK1D	S2464	S2464Y	2464	Missense	central	0	yes	13.202	0.000	EPSD	TCGA;ICGC;COSMIC	11.915	Loss
CK1_CK1_CK1-D_CSNK1D_ST	P25054	APC	P48730	CSNK1D	S2487	S2494F	2494	Missense	distal	7	no	10.557	12.570	EPSD	TCGA;ICGC;COSMIC	11.915	Gain
CK1_CK1_CK1-D_CSNK1D_ST	P25054	APC	P48730	CSNK1D	S2580	K2585I	2585	Missense	distal	5	no	13.437	13.199	EPSD	TCGA;ICGC;COSMIC	11.915	Down-regulation
CK1_CK1_CK1-D_CSNK1D_ST	P25054	APC	P48730	CSNK1D	S2580	L2574I	2574	Missense	distal	-6	no	13.437	13.073	EPSD	TCGA;ICGC;COSMIC	11.915	Down-regulation
CK1_CK1_CK1-D_CSNK1D_ST	P25054	APC	P48730	CSNK1D	S2580	S2577P	2577	Missense	distal	-3	no	13.437	9.438	EPSD	TCGA;ICGC	11.915	Loss
CK1_CK1_CK1-D_CSNK1D_ST	P25054	APC	P48730	CSNK1D	S2581	K2585I	2585	Missense	distal	4	no	12.419	12.109	EPSD	TCGA;ICGC;COSMIC	11.915	Down-regulation
CK1_CK1_CK1-D_CSNK1D_ST	P25054	APC	P48730	CSNK1D	S2581	L2574I	2574	Missense	distal	-7	no	12.419	13.813	EPSD	TCGA;ICGC;COSMIC	11.915	Up-regulation
CK1_CK1_CK1-D_CSNK1D_ST	P25054	APC	P48730	CSNK1D	S2581	S2577P	2577	Missense	distal	-4	no	12.419	11.955	EPSD	TCGA;ICGC	11.915	Down-regulation
CK1_CK1_CK1-D_CSNK1D_ST	P25054	APC	P48730	CSNK1D	T2611	R2613I	2613	Missense	proximal	2	no	11.987	13.062	EPSD	TCGA;ICGC;COSMIC	11.915	Up-regulation
CK1_CK1_CK1-D_CSNK1D_ST	P25054	APC	P48730	CSNK1D	T2629	N2624D	2624	Missense	distal	-5	no	12.809	11.122	EPSD	TCGA;ICGC;COSMIC	11.915	Loss
CK1_CK1_CK1-D_CSNK1D_ST	P25054	APC	P48730	CSNK1D	T2676	S2671Y	2671	Missense	distal	-5	no	12.372	11.192	EPSD	TCGA;ICGC	11.915	Loss
CK1_CK1_CK1-D_CSNK1D_ST	P25054	APC	P48730	CSNK1D	T2676	S2674Y	2674	Missense	proximal	-2	no	12.372	8.650	EPSD	TCGA;ICGC;COSMIC	11.915	Loss
CK1_CK1_CK1-D_CSNK1D_ST	P25054	APC	P48730	CSNK1D	T2782	R2780T	2780	Missense	proximal	-2	no	12.427	14.750	EPSD	TCGA;ICGC;COSMIC	11.915	Up-regulation
CK1_CK1_CK1-D_CSNK1D_ST	P25054	APC	P48730	CSNK1D	T2782	F2784C	2784	Missense	proximal	2	no	12.427	12.266	EPSD	TCGA;ICGC;COSMIC	11.915	Down-regulation
CK1_CK1_CK1-D_CSNK1D_ST	P25054	APC	P48730	CSNK1D	T2782	P2783L	2783	Missense	proximal	1	no	12.427	12.378	EPSD	TCGA;ICGC;COSMIC	11.915	Down-regulation
CK1_CK1_CK1-D_CSNK1D_ST	P25054	APC	P48730	CSNK1D	T2782	G2775V	2775	Missense	distal	-7	no	12.427	10.171	EPSD	TCGA;ICGC;COSMIC	11.915	Loss
CK1_CK1_CK1-D_CSNK1D_ST	P25054	APC	P48730	CSNK1D	T2782	A2779V	2779	Missense	distal	-3	no	12.427	11.620	EPSD	TCGA;ICGC;COSMIC	11.915	Loss
CK1_CK1_CK1-D_CSNK1D_ST	P25054	APC	P48730	CSNK1D	S2797	R2801W	2801	Missense	distal	4	no	12.827	13.288	EPSD	TCGA;ICGC;COSMIC	11.915	Up-regulation
CK1_CK1_CK1-D_CSNK1D_ST	P25054	APC	P48730	CSNK1D	S2797	S2794T	2794	Missense	distal	-3	no	12.827	11.144	EPSD	TCGA;ICGC;COSMIC	11.915	Loss
CK1_CK1_CK1-D_CSNK1D_ST	P25054	APC	P48730	CSNK1D	S2797	Q2804P	2804	Missense	distal	7	no	12.827	11.891	EPSD	TCGA	11.915	Loss
CK1_CK1_CK1-D_CSNK1D_ST	P25054	APC	P48730	CSNK1D	S2826	T2823R	2823	Missense	distal	-3	no	12.151	12.646	EPSD	TCGA;ICGC;COSMIC	11.915	Up-regulation
CK1_CK1_CK1-D_CSNK1D_ST	P04637	TP53	P48730	CSNK1D	S6	P4L	4	Missense	proximal	-2	no	15.860	13.128	EPSD	TCGA;ICGC;COSMIC	11.915	Down-regulation
CK1_CK1_CK1-D_CSNK1D_ST	P04637	TP53	P48730	CSNK1D	S9	P4L	4	Missense	distal	-5	no	18.861	17.228	PhosphoSitePlus;EPSD	TCGA;ICGC;COSMIC	11.915	Down-regulation
CK1_CK1_CK1-D_CSNK1D_ST	P04637	TP53	P48730	CSNK1D	S20	P27S	27	Missense	distal	7	no	12.521	11.660	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	11.915	Loss
CK1_CK1_CK1-D_CSNK1D_ST	P04637	TP53	P48730	CSNK1D	S20	P27L	27	Missense	distal	7	no	12.521	13.465	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC;GDSC;CCLE	11.915	Up-regulation
CK1_CK1_CK1-D_CSNK1D_ST	P04637	TP53	P48730	CSNK1D	S127	K132N	132	Missense	distal	5	no	12.589	12.872	EPSD	TCGA;ICGC;COSMIC;GDSC;CCLE	11.915	Up-regulation
CK1_CK1_CK1-D_CSNK1D_ST	P04637	TP53	P48730	CSNK1D	S127	S121Y	121	Missense	distal	-6	no	12.589	10.569	EPSD	TCGA;ICGC;COSMIC	11.915	Loss
CK1_CK1_CK1-D_CSNK1D_ST	P04637	TP53	P48730	CSNK1D	S127	M133K	133	Missense	distal	6	no	12.589	10.065	EPSD	TCGA;ICGC;COSMIC;CCLE	11.915	Loss
CK1_CK1_CK1-D_CSNK1D_ST	P04637	TP53	P48730	CSNK1D	S127	K132E	132	Missense	distal	5	no	12.589	12.465	EPSD	TCGA;ICGC;COSMIC;GDSC;CCLE	11.915	Down-regulation
CK1_CK1_CK1-D_CSNK1D_ST	P04637	TP53	P48730	CSNK1D	S127	Y126C	126	Missense	proximal	-1	no	12.589	13.293	EPSD	TCGA;ICGC;COSMIC;GDSC	11.915	Up-regulation
CK1_CK1_CK1-D_CSNK1D_ST	P04637	TP53	P48730	CSNK1D	S127	S127P	127	Missense	central	0	yes	12.589	0.000	EPSD	TCGA;ICGC;COSMIC;GDSC;CCLE	11.915	Loss
CK1_CK1_CK1-D_CSNK1D_ST	P04637	TP53	P48730	CSNK1D	S127	Y126N	126	Missense	proximal	-1	no	12.589	14.117	EPSD	TCGA;ICGC;COSMIC	11.915	Up-regulation
CK1_CK1_CK1-D_CSNK1D_ST	P04637	TP53	P48730	CSNK1D	S127	L130V	130	Missense	distal	3	no	12.589	10.877	EPSD	TCGA;ICGC;COSMIC;GDSC;CCLE	11.915	Loss
CK1_CK1_CK1-D_CSNK1D_ST	P04637	TP53	P48730	CSNK1D	S127	K132T	132	Missense	distal	5	no	12.589	11.850	EPSD	TCGA;ICGC;COSMIC;GDSC;CCLE	11.915	Loss
CK1_CK1_CK1-D_CSNK1D_ST	P04637	TP53	P48730	CSNK1D	S127	S127Y	127	Missense	central	0	yes	12.589	0.000	EPSD	TCGA;ICGC;COSMIC	11.915	Loss
CK1_CK1_CK1-D_CSNK1D_ST	P04637	TP53	P48730	CSNK1D	S127	S127F	127	Missense	central	0	yes	12.589	0.000	EPSD	TCGA;ICGC;COSMIC;CCLE	11.915	Loss
CK1_CK1_CK1-D_CSNK1D_ST	P04637	TP53	P48730	CSNK1D	S127	M133R	133	Missense	distal	6	no	12.589	8.792	EPSD	TCGA;ICGC;COSMIC	11.915	Loss
CK1_CK1_CK1-D_CSNK1D_ST	P04637	TP53	P48730	CSNK1D	S127	K132R	132	Missense	distal	5	no	12.589	12.638	EPSD	TCGA;ICGC;COSMIC;GDSC;CCLE	11.915	Up-regulation
CK1_CK1_CK1-D_CSNK1D_ST	P04637	TP53	P48730	CSNK1D	S127	F134L	134	Missense	distal	7	no	12.589	12.381	EPSD	TCGA;ICGC;COSMIC;CCLE	11.915	Down-regulation
CK1_CK1_CK1-D_CSNK1D_ST	P04637	TP53	P48730	CSNK1D	S127	Y126S	126	Missense	proximal	-1	no	12.589	13.782	EPSD	TCGA;ICGC;COSMIC	11.915	Up-regulation
CK1_CK1_CK1-D_CSNK1D_ST	P04637	TP53	P48730	CSNK1D	S127	L130P	130	Missense	distal	3	no	12.589	11.608	EPSD	TCGA;ICGC;COSMIC	11.915	Loss
CK1_CK1_CK1-D_CSNK1D_ST	P04637	TP53	P48730	CSNK1D	S127	L130F	130	Missense	distal	3	no	12.589	13.217	EPSD	TCGA;ICGC;COSMIC;CCLE	11.915	Up-regulation
CK1_CK1_CK1-D_CSNK1D_ST	P04637	TP53	P48730	CSNK1D	S127	F134V	134	Missense	distal	7	no	12.589	11.957	EPSD	TCGA;ICGC;COSMIC	11.915	Down-regulation
CK1_CK1_CK1-D_CSNK1D_ST	P04637	TP53	P48730	CSNK1D	S127	T125M	125	Missense	proximal	-2	no	12.589	9.343	EPSD	TCGA;ICGC;COSMIC;GDSC	11.915	Loss
CK1_CK1_CK1-D_CSNK1D_ST	P04637	TP53	P48730	CSNK1D	S127	Y126D	126	Missense	proximal	-1	no	12.589	14.119	EPSD	TCGA;ICGC;COSMIC;GDSC	11.915	Up-regulation
CK1_CK1_CK1-D_CSNK1D_ST	P04637	TP53	P48730	CSNK1D	S127	K120E	120	Missense	distal	-7	no	12.589	14.521	EPSD	TCGA;ICGC;COSMIC	11.915	Up-regulation
CK1_CK1_CK1-D_CSNK1D_ST	P04637	TP53	P48730	CSNK1D	S127	N131S	131	Missense	distal	4	no	12.589	12.894	EPSD	TCGA;ICGC;COSMIC	11.915	Up-regulation
CK1_CK1_CK1-D_CSNK1D_ST	P04637	TP53	P48730	CSNK1D	S127	T125P	125	Missense	proximal	-2	no	12.589	10.092	EPSD	TCGA;ICGC;COSMIC;CCLE	11.915	Loss
CK1_CK1_CK1-D_CSNK1D_ST	P04637	TP53	P48730	CSNK1D	S127	S127C	127	Missense	central	0	yes	12.589	0.000	EPSD	TCGA;ICGC;COSMIC;CCLE	11.915	Loss
CK1_CK1_CK1-D_CSNK1D_ST	P04637	TP53	P48730	CSNK1D	S127	N131I	131	Missense	distal	4	no	12.589	12.824	EPSD	TCGA;ICGC;COSMIC	11.915	Up-regulation
CK1_CK1_CK1-D_CSNK1D_ST	P04637	TP53	P48730	CSNK1D	S127	Y126H	126	Missense	proximal	-1	no	12.589	12.384	EPSD	TCGA;ICGC;COSMIC;GDSC	11.915	Down-regulation
CK1_CK1_CK1-D_CSNK1D_ST	P04637	TP53	P48730	CSNK1D	S127	K132Q	132	Missense	distal	5	no	12.589	12.002	EPSD	TCGA;ICGC;COSMIC;GDSC;CCLE	11.915	Down-regulation
CK1_CK1_CK1-D_CSNK1D_ST	P04637	TP53	P48730	CSNK1D	S127	L130R	130	Missense	distal	3	no	12.589	11.133	EPSD	TCGA;ICGC;COSMIC;CCLE	11.915	Loss
CK1_CK1_CK1-D_CSNK1D_ST	P49810	PSEN2	P48730	CSNK1D	S9	C14F	14	Missense	distal	5	no	13.968	13.132	EPSD	TCGA;ICGC;COSMIC	11.915	Down-regulation
CK1_CK1_CK1-D_CSNK1D_ST	P49810	PSEN2	P48730	CSNK1D	T18	C14F	14	Missense	distal	-4	no	13.520	13.280	EPSD	TCGA;ICGC;COSMIC	11.915	Down-regulation
CK1_CK1_CK1-D_CSNK1D_ST	P49810	PSEN2	P48730	CSNK1D	S19	C14F	14	Missense	distal	-5	no	14.760	14.685	EPSD	TCGA;ICGC;COSMIC	11.915	Down-regulation
CK1_CK1_CK1-D_CSNK1D_ST	P49810	PSEN2	P48730	CSNK1D	T27	R29H	29	Missense	proximal	2	no	15.278	14.430	EPSD	TCGA;ICGC;COSMIC	11.915	Down-regulation
CK1_CK1_CK1-D_CSNK1D_ST	P49810	PSEN2	P48730	CSNK1D	T27	E33G	33	Missense	distal	6	no	15.278	13.647	EPSD	TCGA;COSMIC	11.915	Down-regulation
CK1_CK1_CK1-D_CSNK1D_ST	P49810	PSEN2	P48730	CSNK1D	T27	T27M	27	Missense	central	0	yes	15.278	0.000	EPSD	TCGA;ICGC;COSMIC	11.915	Loss
CK1_CK1_CK1-D_CSNK1D_ST	P49810	PSEN2	P48730	CSNK1D	S327	D326N	326	Missense	proximal	-1	no	18.777	18.775	EPSD;PhosphoSitePlus	TCGA	11.915	Down-regulation
CK1_CK1_CK1-D_CSNK1D_ST	P49810	PSEN2	P48730	CSNK1D	S327	E322K	322	Missense	distal	-5	no	18.777	17.199	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	11.915	Down-regulation
CK1_CK1_CK1-D_CSNK1D_ST	P49810	PSEN2	P48730	CSNK1D	S330	P337L	337	Missense	distal	7	no	13.880	14.825	PhosphoSitePlus;EPSD	TCGA;COSMIC	11.915	Up-regulation
CK1_CK1_CK1-D_CSNK1D_ST	P49810	PSEN2	P48730	CSNK1D	S330	D326N	326	Missense	distal	-4	no	13.880	13.874	PhosphoSitePlus;EPSD	TCGA	11.915	Down-regulation
CK1_CK1_CK1-D_CSNK1D_ST	P35222	CTNNB1	P48730	CSNK1D	T3	T3A	3	Missense	central	0	yes	15.968	0.000	EPSD	TCGA;COSMIC	11.915	Loss
CK1_CK1_CK1-D_CSNK1D_ST	P35222	CTNNB1	P48730	CSNK1D	T3	D6A	6	Missense	distal	3	no	15.968	16.446	EPSD	TCGA;ICGC;COSMIC	11.915	Up-regulation
CK1_CK1_CK1-D_CSNK1D_ST	P35222	CTNNB1	P48730	CSNK1D	S33	G34R	34	Missense	proximal	1	no	14.040	12.220	EPSD	TCGA;COSMIC	11.915	Down-regulation
CK1_CK1_CK1-D_CSNK1D_ST	P35222	CTNNB1	P48730	CSNK1D	S33	G34V	34	Missense	proximal	1	no	14.040	14.145	EPSD	TCGA;COSMIC;CCLE	11.915	Up-regulation
CK1_CK1_CK1-D_CSNK1D_ST	P35222	CTNNB1	P48730	CSNK1D	S33	G34E	34	Missense	proximal	1	no	14.040	13.426	EPSD	TCGA;COSMIC;GDSC;CCLE	11.915	Down-regulation
CK1_CK1_CK1-D_CSNK1D_ST	P35222	CTNNB1	P48730	CSNK1D	S33	S37C	37	Missense	distal	4	no	14.040	14.059	EPSD	TCGA;COSMIC;GDSC;CCLE	11.915	Up-regulation
CK1_CK1_CK1-D_CSNK1D_ST	P35222	CTNNB1	P48730	CSNK1D	S33	S37F	37	Missense	distal	4	no	14.040	14.463	EPSD	TCGA;COSMIC;GDSC;CCLE	11.915	Up-regulation
CK1_CK1_CK1-D_CSNK1D_ST	P35222	CTNNB1	P48730	CSNK1D	S33	S33F	33	Missense	central	0	yes	14.040	0.000	EPSD	TCGA;COSMIC;GDSC;CCLE	11.915	Loss
CK1_CK1_CK1-D_CSNK1D_ST	P35222	CTNNB1	P48730	CSNK1D	S33	D32H	32	Missense	proximal	-1	no	14.040	12.305	EPSD	TCGA;COSMIC	11.915	Down-regulation
CK1_CK1_CK1-D_CSNK1D_ST	P35222	CTNNB1	P48730	CSNK1D	S33	D32G	32	Missense	proximal	-1	no	14.040	13.643	EPSD	TCGA;COSMIC	11.915	Down-regulation
CK1_CK1_CK1-D_CSNK1D_ST	P35222	CTNNB1	P48730	CSNK1D	S33	S33A	33	Missense	central	0	yes	14.040	0.000	EPSD	TCGA;COSMIC	11.915	Loss
CK1_CK1_CK1-D_CSNK1D_ST	P35222	CTNNB1	P48730	CSNK1D	S33	S33Y	33	Missense	central	0	yes	14.040	0.000	EPSD	TCGA;COSMIC;GDSC;CCLE	11.915	Loss
CK1_CK1_CK1-D_CSNK1D_ST	P35222	CTNNB1	P48730	CSNK1D	S33	D32V	32	Missense	proximal	-1	no	14.040	13.967	EPSD	TCGA;COSMIC;CCLE	11.915	Down-regulation
CK1_CK1_CK1-D_CSNK1D_ST	P35222	CTNNB1	P48730	CSNK1D	S33	S33P	33	Missense	central	0	yes	14.040	0.000	EPSD	TCGA;COSMIC;CCLE	11.915	Loss
CK1_CK1_CK1-D_CSNK1D_ST	P35222	CTNNB1	P48730	CSNK1D	S33	H36P	36	Missense	distal	3	no	14.040	12.434	EPSD	TCGA;COSMIC;CCLE	11.915	Down-regulation
CK1_CK1_CK1-D_CSNK1D_ST	P35222	CTNNB1	P48730	CSNK1D	S33	D32Y	32	Missense	proximal	-1	no	14.040	12.510	EPSD	TCGA;COSMIC;CCLE	11.915	Down-regulation
CK1_CK1_CK1-D_CSNK1D_ST	P35222	CTNNB1	P48730	CSNK1D	S33	I35S	35	Missense	proximal	2	no	14.040	13.198	EPSD	TCGA;COSMIC	11.915	Down-regulation
CK1_CK1_CK1-D_CSNK1D_ST	P35222	CTNNB1	P48730	CSNK1D	S33	S37Y	37	Missense	distal	4	no	14.040	14.642	EPSD	TCGA;COSMIC	11.915	Up-regulation
CK1_CK1_CK1-D_CSNK1D_ST	P35222	CTNNB1	P48730	CSNK1D	S33	S33C	33	Missense	central	0	yes	14.040	0.000	EPSD	TCGA;COSMIC;GDSC;CCLE	11.915	Loss
CK1_CK1_CK1-D_CSNK1D_ST	P35222	CTNNB1	P48730	CSNK1D	S33	S37A	37	Missense	distal	4	no	14.040	13.871	EPSD	TCGA;COSMIC;GDSC;CCLE	11.915	Down-regulation
CK1_CK1_CK1-D_CSNK1D_ST	P35222	CTNNB1	P48730	CSNK1D	S33	D32N	32	Missense	proximal	-1	no	14.040	14.038	EPSD	TCGA;COSMIC;CCLE	11.915	Down-regulation
CK1_CK1_CK1-D_CSNK1D_ST	P35222	CTNNB1	P48730	CSNK1D	S33	S37P	37	Missense	distal	4	no	14.040	14.345	EPSD	TCGA;COSMIC;GDSC;CCLE	11.915	Up-regulation
CK1_CK1_CK1-D_CSNK1D_ST	P35222	CTNNB1	P48730	CSNK1D	S33	D32A	32	Missense	proximal	-1	no	14.040	14.514	EPSD	TCGA;COSMIC	11.915	Up-regulation
CK1_CK1_CK1-D_CSNK1D_ST	P35222	CTNNB1	P48730	CSNK1D	T40	G34E	34	Missense	distal	-6	no	11.145	12.052	EPSD	TCGA;COSMIC;GDSC;CCLE	11.915	Gain
CK1_CK1_CK1-D_CSNK1D_ST	P35222	CTNNB1	P48730	CSNK1D	T40	I35S	35	Missense	distal	-5	no	11.145	12.288	EPSD	TCGA;COSMIC	11.915	Gain
CK1_CK1_CK1-D_CSNK1D_ST	P35222	CTNNB1	P48730	CSNK1D	T41	S45F	45	Missense	distal	4	no	11.711	12.134	EPSD	TCGA;COSMIC;GDSC;CCLE	11.915	Gain
CK1_CK1_CK1-D_CSNK1D_ST	P35222	CTNNB1	P48730	CSNK1D	T41	S45P	45	Missense	distal	4	no	11.711	12.016	EPSD	TCGA;COSMIC;CCLE	11.915	Gain
CK1_CK1_CK1-D_CSNK1D_ST	P35222	CTNNB1	P48730	CSNK1D	T41	G34E	34	Missense	distal	-7	no	11.711	12.035	EPSD	TCGA;COSMIC;GDSC;CCLE	11.915	Gain
CK1_CK1_CK1-D_CSNK1D_ST	P35222	CTNNB1	P48730	CSNK1D	T41	S45Y	45	Missense	distal	4	no	11.711	12.313	EPSD	TCGA;COSMIC	11.915	Gain
CK1_CK1_CK1-D_CSNK1D_ST	P35222	CTNNB1	P48730	CSNK1D	T41	H36P	36	Missense	distal	-5	no	11.711	13.666	EPSD	TCGA;COSMIC;CCLE	11.915	Gain
CK1_CK1_CK1-D_CSNK1D_ST	P35222	CTNNB1	P48730	CSNK1D	T41	I35S	35	Missense	distal	-6	no	11.711	12.770	EPSD	TCGA;COSMIC	11.915	Gain
CK1_CK1_CK1-D_CSNK1D_ST	P35222	CTNNB1	P48730	CSNK1D	T41	S37A	37	Missense	distal	-4	no	11.711	12.012	EPSD	TCGA;COSMIC;GDSC;CCLE	11.915	Gain
CK1_CK1_CK1-D_CSNK1D_ST	P35222	CTNNB1	P48730	CSNK1D	S45	S45F	45	Missense	central	0	yes	13.837	0.000	PhosphoSitePlus	TCGA;COSMIC;GDSC;CCLE	11.915	Loss
CK1_CK1_CK1-D_CSNK1D_ST	P35222	CTNNB1	P48730	CSNK1D	S45	S45P	45	Missense	central	0	yes	13.837	0.000	PhosphoSitePlus	TCGA;COSMIC;CCLE	11.915	Loss
CK1_CK1_CK1-D_CSNK1D_ST	P35222	CTNNB1	P48730	CSNK1D	S45	T41A	41	Missense	distal	-4	no	13.837	14.534	PhosphoSitePlus	TCGA;COSMIC;GDSC;CCLE	11.915	Up-regulation
CK1_CK1_CK1-D_CSNK1D_ST	P35222	CTNNB1	P48730	CSNK1D	S45	T41I	41	Missense	distal	-4	no	13.837	14.213	PhosphoSitePlus	TCGA;COSMIC	11.915	Up-regulation
CK1_CK1_CK1-D_CSNK1D_ST	P35222	CTNNB1	P48730	CSNK1D	S45	S45Y	45	Missense	central	0	yes	13.837	0.000	PhosphoSitePlus	TCGA;COSMIC	11.915	Loss
CK1_CK1_CK1-D_CSNK1D_ST	P35222	CTNNB1	P48730	CSNK1D	S45	T41N	41	Missense	distal	-4	no	13.837	13.985	PhosphoSitePlus	TCGA;COSMIC	11.915	Up-regulation
CK1_CK1_CK1-D_CSNK1D_ST	P35222	CTNNB1	P48730	CSNK1D	S45	S45C	45	Missense	central	0	yes	13.837	0.000	PhosphoSitePlus	TCGA;COSMIC;GDSC;CCLE	11.915	Loss
CK1_CK1_CK1-D_CSNK1D_ST	P35222	CTNNB1	P48730	CSNK1D	T59	S60F	60	Missense	proximal	1	no	14.261	15.652	EPSD	TCGA;COSMIC	11.915	Up-regulation
CK1_CK1_CK1-D_CSNK1D_ST	P35222	CTNNB1	P48730	CSNK1D	T59	E54D	54	Missense	distal	-5	no	14.261	13.241	EPSD	TCGA;COSMIC	11.915	Down-regulation
CK1_CK1_CK1-D_CSNK1D_ST	P35222	CTNNB1	P48730	CSNK1D	T59	E55K	55	Missense	distal	-4	no	14.261	14.111	EPSD	TCGA;COSMIC	11.915	Down-regulation
CK1_CK1_CK1-D_CSNK1D_ST	P35222	CTNNB1	P48730	CSNK1D	S179	R185G	185	Missense	distal	6	no	13.351	14.791	EPSD	TCGA;COSMIC	11.915	Up-regulation
CK1_CK1_CK1-D_CSNK1D_ST	P35222	CTNNB1	P48730	CSNK1D	T393	R386G	386	Missense	distal	-7	no	10.129	11.942	EPSD	TCGA;COSMIC	11.915	Gain
CK1_CK1_CK1-D_CSNK1D_ST	P35222	CTNNB1	P48730	CSNK1D	T393	K394E	394	Missense	proximal	1	no	10.129	13.511	EPSD	TCGA	11.915	Gain
CK1_CK1_CK1-D_CSNK1D_ST	P35222	CTNNB1	P48730	CSNK1D	T547	R542H	542	Missense	distal	-5	no	12.866	11.015	EPSD	TCGA;COSMIC	11.915	Loss
CK1_CK1_CK1-D_CSNK1D_ST	P35222	CTNNB1	P48730	CSNK1D	T547	M553V	553	Missense	distal	6	no	12.866	9.242	EPSD	TCGA;COSMIC	11.915	Loss
CK1_CK1_CK1-D_CSNK1D_ST	P35222	CTNNB1	P48730	CSNK1D	T547	V541A	541	Missense	distal	-6	no	12.866	13.178	EPSD	TCGA;COSMIC	11.915	Up-regulation
CK1_CK1_CK1-D_CSNK1D_ST	P35222	CTNNB1	P48730	CSNK1D	T653	S646C	646	Missense	distal	-7	no	13.053	12.009	EPSD	TCGA;COSMIC	11.915	Down-regulation
CK1_CK1_CK1-D_CSNK1D_ST	P35222	CTNNB1	P48730	CSNK1D	T653	E649Q	649	Missense	distal	-4	no	13.053	12.953	EPSD	TCGA;COSMIC	11.915	Down-regulation
CK1_CK1_CK1-D_CSNK1D_ST	P35222	CTNNB1	P48730	CSNK1D	T653	T653K	653	Missense	central	0	yes	13.053	0.000	EPSD	TCGA;COSMIC	11.915	Loss
CK1_CK1_CK1-D_CSNK1D_ST	Q14511	NEDD9	P48730	CSNK1D	T126	G125D	125	Missense	proximal	-1	no	11.809	12.207	EPSD	TCGA;ICGC;COSMIC	11.915	Gain
CK1_CK1_CK1-D_CSNK1D_ST	Q14511	NEDD9	P48730	CSNK1D	T126	Q119E	119	Missense	distal	-7	no	11.809	13.267	EPSD	TCGA;ICGC;COSMIC	11.915	Gain
CK1_CK1_CK1-D_CSNK1D_ST	Q14511	NEDD9	P48730	CSNK1D	S298	S298F	298	Missense	central	0	yes	12.728	0.000	EPSD	TCGA;ICGC;COSMIC	11.915	Loss
CK1_CK1_CK1-D_CSNK1D_ST	Q14511	NEDD9	P48730	CSNK1D	S309	A316T	316	Missense	distal	7	no	10.355	12.150	EPSD	TCGA;ICGC;COSMIC;GDSC;CCLE	11.915	Gain
CK1_CK1_CK1-D_CSNK1D_ST	Q14511	NEDD9	P48730	CSNK1D	S375	S369P	369	Missense	distal	-6	no	15.892	14.249	EPSD	TCGA	11.915	Down-regulation
CK1_CK1_CK1-D_CSNK1D_ST	Q14511	NEDD9	P48730	CSNK1D	S395	S393L	393	Missense	proximal	-2	no	14.119	10.498	EPSD	TCGA;ICGC;COSMIC	11.915	Loss
CK1_CK1_CK1-D_CSNK1D_ST	Q14511	NEDD9	P48730	CSNK1D	S621	D627Y	627	Missense	distal	6	no	13.835	11.882	EPSD	TCGA;ICGC;COSMIC	11.915	Loss
CK1_CK1_CK1-D_CSNK1D_ST	Q14511	NEDD9	P48730	CSNK1D	T804	T805M	805	Missense	proximal	1	no	15.147	14.949	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	11.915	Down-regulation
CK1_CK1_CK1-D_CSNK1D_ST	Q14511	NEDD9	P48730	CSNK1D	T804	T805K	805	Missense	proximal	1	no	15.147	13.167	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	11.915	Down-regulation
CK1_CK1_CK1-D_CSNK1D_ST	P46937	YAP1	P48730	CSNK1D	T119	Q121H	121	Missense	proximal	2	no	13.730	12.771	EPSD	TCGA;ICGC;COSMIC	11.915	Down-regulation
CK1_CK1_CK1-D_CSNK1D_ST	P46937	YAP1	P48730	CSNK1D	T119	R124P	124	Missense	distal	5	no	13.730	13.924	EPSD	TCGA;ICGC;COSMIC	11.915	Up-regulation
CK1_CK1_CK1-D_CSNK1D_ST	P46937	YAP1	P48730	CSNK1D	T119	R124Q	124	Missense	distal	5	no	13.730	13.094	EPSD	TCGA;ICGC;COSMIC	11.915	Down-regulation
CK1_CK1_CK1-D_CSNK1D_ST	P46937	YAP1	P48730	CSNK1D	S164	I167M	167	Missense	distal	3	no	10.651	13.097	EPSD	TCGA;ICGC	11.915	Gain
CK1_CK1_CK1-D_CSNK1D_ST	P46937	YAP1	P48730	CSNK1D	S217	A214T	214	Missense	distal	-3	no	12.270	13.122	EPSD	TCGA;ICGC	11.915	Up-regulation
CK1_CK1_CK1-D_CSNK1D_ST	P46937	YAP1	P48730	CSNK1D	S274	S276N	276	Missense	proximal	2	no	12.283	12.132	EPSD	TCGA;ICGC	11.915	Down-regulation
CK1_CK1_CK1-D_CSNK1D_ST	P46937	YAP1	P48730	CSNK1D	S274	A268G	268	Missense	distal	-6	no	12.283	11.477	EPSD	TCGA;ICGC;COSMIC	11.915	Loss
CK1_CK1_CK1-D_CSNK1D_ST	P46937	YAP1	P48730	CSNK1D	S274	Q275H	275	Missense	proximal	1	no	12.283	13.883	EPSD	TCGA;ICGC;COSMIC	11.915	Up-regulation
CK1_CK1_CK1-D_CSNK1D_ST	P46937	YAP1	P48730	CSNK1D	S340	I333N	333	Missense	distal	-7	no	11.201	12.244	EPSD	TCGA;ICGC;COSMIC	11.915	Gain
CK1_CK1_CK1-D_CSNK1D_ST	P46937	YAP1	P48730	CSNK1D	S400	E396D	396	Missense	distal	-4	no	16.819	16.679	EPSD	TCGA;ICGC;COSMIC	11.915	Down-regulation
CK1_CK1_CK1-D_CSNK1D_ST	O43312	MTSS1	P48730	CSNK1D	S285	S292L	292	Missense	distal	7	no	10.536	12.341	EPSD	TCGA;COSMIC	11.915	Gain
CK1_CK1_CK1-D_CSNK1D_ST	O43312	MTSS1	P48730	CSNK1D	S290	S297A	297	Missense	distal	7	no	11.802	12.262	EPSD	TCGA;COSMIC	11.915	Gain
CK1_CK1_CK1-D_CSNK1D_ST	O43312	MTSS1	P48730	CSNK1D	S290	S294F	294	Missense	distal	4	no	11.802	12.225	EPSD	TCGA;COSMIC	11.915	Gain
CK1_CK1_CK1-D_CSNK1D_ST	O43312	MTSS1	P48730	CSNK1D	S290	G289V	289	Missense	proximal	-1	no	11.802	12.126	EPSD	TCGA;COSMIC	11.915	Gain
CK1_CK1_CK1-D_CSNK1D_ST	O43312	MTSS1	P48730	CSNK1D	S322	A329V	329	Missense	distal	7	no	12.960	13.882	PhosphoSitePlus	TCGA;COSMIC	11.915	Up-regulation
CK1_CK1_CK1-D_CSNK1D_ST	O43312	MTSS1	P48730	CSNK1D	S446	A451V	451	Missense	distal	5	no	14.585	14.068	EPSD	TCGA;COSMIC	11.915	Down-regulation
CK1_CK1_CK1-D_CSNK1D_ST	O43312	MTSS1	P48730	CSNK1D	S555	R550T	550	Missense	distal	-5	no	12.852	11.528	EPSD	TCGA;COSMIC	11.915	Loss
CK1_CK1_CK1-D_CSNK1D_ST	O43312	MTSS1	P48730	CSNK1D	S555	R559Q	559	Missense	distal	4	no	12.852	12.893	EPSD	TCGA;COSMIC	11.915	Up-regulation
CK1_CK1_CK1-D_CSNK1D_ST	O43312	MTSS1	P48730	CSNK1D	S555	D553N	553	Missense	proximal	-2	no	12.852	10.519	EPSD	TCGA;COSMIC	11.915	Loss
CK1_CK1_CK1-D_CSNK1D_ST	O43312	MTSS1	P48730	CSNK1D	T658	T658A	658	Missense	central	0	yes	14.453	0.000	EPSD	TCGA;COSMIC	11.915	Loss
CK1_CK1_CK1-D_CSNK1D_ST	O43312	MTSS1	P48730	CSNK1D	T658	G656V	656	Missense	proximal	-2	no	14.453	12.416	EPSD	TCGA;COSMIC	11.915	Down-regulation
CK1_CK1_CK1-D_CSNK1D_ST	O43312	MTSS1	P48730	CSNK1D	S666	G667D	667	Missense	proximal	1	no	13.216	12.684	EPSD	TCGA;COSMIC	11.915	Down-regulation
CK1_CK1_CK1-D_CSNK1D_ST	O43312	MTSS1	P48730	CSNK1D	S666	S666R	666	Missense	central	0	yes	13.216	0.000	EPSD	TCGA;COSMIC	11.915	Loss
CK1_CK1_CK1-D_CSNK1D_ST	Q9BZL6	PRKD2	P48730	CSNK1D	S200	S206L	206	Missense	distal	6	no	14.712	13.027	EPSD	TCGA;COSMIC	11.915	Down-regulation
CK1_CK1_CK1-D_CSNK1D_ST	Q9BZL6	PRKD2	P48730	CSNK1D	S200	R195C	195	Missense	distal	-5	no	14.712	14.234	EPSD	TCGA;COSMIC	11.915	Down-regulation
CK1_CK1_CK1-D_CSNK1D_ST	Q9BZL6	PRKD2	P48730	CSNK1D	S200	K193E	193	Missense	distal	-7	no	14.712	16.645	EPSD	TCGA;COSMIC	11.915	Up-regulation
CK1_CK1_CK1-D_CSNK1D_ST	Q9BZL6	PRKD2	P48730	CSNK1D	S200	S203T	203	Missense	distal	3	no	14.712	13.176	EPSD	TCGA;COSMIC	11.915	Down-regulation
CK1_CK1_CK1-D_CSNK1D_ST	Q9BZL6	PRKD2	P48730	CSNK1D	S200	R195H	195	Missense	distal	-5	no	14.712	12.862	EPSD	TCGA;COSMIC	11.915	Down-regulation
CK1_CK1_CK1-D_CSNK1D_ST	Q9BZL6	PRKD2	P48730	CSNK1D	S200	R194W	194	Missense	distal	-6	no	14.712	13.184	EPSD	TCGA	11.915	Down-regulation
CK1_CK1_CK1-D_CSNK1D_ST	Q9BZL6	PRKD2	P48730	CSNK1D	S200	T199M	199	Missense	proximal	-1	no	14.712	14.404	EPSD	TCGA	11.915	Down-regulation
CK1_CK1_CK1-D_CSNK1D_ST	Q9BZL6	PRKD2	P48730	CSNK1D	S223	R224H	224	Missense	proximal	1	no	14.388	16.507	EPSD	TCGA;COSMIC	11.915	Up-regulation
CK1_CK1_CK1-D_CSNK1D_ST	Q9BZL6	PRKD2	P48730	CSNK1D	S223	E228K	228	Missense	distal	5	no	14.388	14.512	EPSD	TCGA;COSMIC;CCLE	11.915	Up-regulation
CK1_CK1_CK1-D_CSNK1D_ST	Q9BZL6	PRKD2	P48730	CSNK1D	S344	E345Q	345	Missense	proximal	1	no	13.396	12.711	EPSD	TCGA;COSMIC;CCLE	11.915	Down-regulation
CK1_CK1_CK1-D_CSNK1D_ST	Q9BZL6	PRKD2	P48730	CSNK1D	S344	A339T	339	Missense	distal	-5	no	13.396	11.535	EPSD	TCGA;COSMIC	11.915	Loss
CK1_CK1_CK1-D_CSNK1D_ST	Q9BZL6	PRKD2	P48730	CSNK1D	S362	E363K	363	Missense	proximal	1	no	16.185	12.804	EPSD	TCGA;COSMIC	11.915	Down-regulation
CK1_CK1_CK1-D_CSNK1D_ST	Q9BZL6	PRKD2	P48730	CSNK1D	S362	E356G	356	Missense	distal	-6	no	16.185	15.278	EPSD	TCGA;COSMIC	11.915	Down-regulation
CK1_CK1_CK1-D_CSNK1D_ST	Q9BZL6	PRKD2	P48730	CSNK1D	S375	P380L	380	Missense	distal	5	no	13.244	12.123	EPSD	TCGA;COSMIC	11.915	Down-regulation
CK1_CK1_CK1-D_CSNK1D_ST	Q9BZL6	PRKD2	P48730	CSNK1D	S375	M382T	382	Missense	distal	7	no	13.244	13.912	EPSD	TCGA;COSMIC	11.915	Up-regulation
CK1_CK1_CK1-D_CSNK1D_ST	Q9BZL6	PRKD2	P48730	CSNK1D	S797	R795H	795	Missense	proximal	-2	no	9.923	12.071	EPSD	TCGA;COSMIC	11.915	Gain
CK1_CK1_CK1-D_CSNK1D_ST	P43629	KIR3DL1	P48730	CSNK1D	S246	S239N	239	Missense	distal	-7	no	15.252	15.989	EPSD	TCGA;ICGC;COSMIC	11.915	Up-regulation
CK1_CK1_CK1-D_CSNK1D_ST	P43629	KIR3DL1	P48730	CSNK1D	S246	S249C	249	Missense	distal	3	no	15.252	12.240	EPSD	TCGA;ICGC;COSMIC	11.915	Down-regulation
CK1_CK1_CK1-D_CSNK1D_ST	P43629	KIR3DL1	P48730	CSNK1D	S246	M252I	252	Missense	distal	6	no	15.252	11.651	EPSD	TCGA;ICGC;COSMIC;GDSC;CCLE	11.915	Loss
CK1_CK1_CK1-D_CSNK1D_ST	P43629	KIR3DL1	P48730	CSNK1D	S246	S246F	246	Missense	central	0	yes	15.252	0.000	EPSD	TCGA;ICGC;COSMIC	11.915	Loss
CK1_CK1_CK1-D_CSNK1D_ST	P43629	KIR3DL1	P48730	CSNK1D	S385	D389N	389	Missense	distal	4	no	15.402	14.701	EPSD;PhosphoSitePlus	TCGA;COSMIC	11.915	Down-regulation
CK1_CK1_CK1-D_CSNK1D_ST	P43629	KIR3DL1	P48730	CSNK1D	S385	E390K	390	Missense	distal	5	no	15.402	15.526	EPSD;PhosphoSitePlus	TCGA;COSMIC	11.915	Up-regulation
CK1_CK1_CK1-D_CSNK1D_ST	P43629	KIR3DL1	P48730	CSNK1D	S388	P393R	393	Missense	distal	5	no	19.910	19.716	PhosphoSitePlus;EPSD	TCGA;COSMIC	11.915	Down-regulation
CK1_CK1_CK1-D_CSNK1D_ST	P43629	KIR3DL1	P48730	CSNK1D	S388	D389N	389	Missense	proximal	1	no	19.910	18.602	PhosphoSitePlus;EPSD	TCGA;COSMIC	11.915	Down-regulation
CK1_CK1_CK1-D_CSNK1D_ST	P43629	KIR3DL1	P48730	CSNK1D	S388	E395K	395	Missense	distal	7	no	19.910	20.152	PhosphoSitePlus;EPSD	TCGA;ICGC;COSMIC;GDSC;CCLE	11.915	Up-regulation
CK1_CK1_CK1-D_CSNK1D_ST	P43629	KIR3DL1	P48730	CSNK1D	S388	E390K	390	Missense	proximal	2	no	19.910	19.148	PhosphoSitePlus;EPSD	TCGA;COSMIC	11.915	Down-regulation
CK1_CK1_CK1-D_CSNK1D_ST	Q9Y6Q9	NCOA3	P48730	CSNK1D	S551	P552L	552	Missense	proximal	1	no	13.774	13.725	EPSD	TCGA;ICGC;COSMIC	11.915	Down-regulation
CK1_CK1_CK1-D_CSNK1D_ST	Q9Y6Q9	NCOA3	P48730	CSNK1D	S601	A606S	606	Missense	distal	5	no	19.748	20.135	PhosphoSitePlus	TCGA;ICGC;COSMIC	11.915	Up-regulation
CK1_CK1_CK1-D_CSNK1D_ST	Q9Y6Q9	NCOA3	P48730	CSNK1D	S601	E607D	607	Missense	distal	6	no	19.748	18.704	PhosphoSitePlus	TCGA	11.915	Down-regulation
CK1_CK1_CK1-D_CSNK1D_ST	Q9Y6Q9	NCOA3	P48730	CSNK1D	S602	A606S	606	Missense	distal	4	no	13.759	13.928	EPSD	TCGA;ICGC;COSMIC	11.915	Up-regulation
CK1_CK1_CK1-D_CSNK1D_ST	Q9Y6Q9	NCOA3	P48730	CSNK1D	S602	E607D	607	Missense	distal	5	no	13.759	13.735	EPSD	TCGA	11.915	Down-regulation
CK1_CK1_CK1-D_CSNK1D_ST	Q9Y6Q9	NCOA3	P48730	CSNK1D	S652	K647R	647	Missense	distal	-5	no	15.054	15.490	EPSD	TCGA;ICGC;COSMIC	11.915	Up-regulation
CK1_CK1_CK1-D_CSNK1D_ST	Q9Y6Q9	NCOA3	P48730	CSNK1D	S655	S662C	662	Missense	distal	7	no	13.926	12.538	EPSD	TCGA;COSMIC	11.915	Down-regulation
CK1_CK1_CK1-D_CSNK1D_ST	Q9Y6Q9	NCOA3	P48730	CSNK1D	T663	S662C	662	Missense	proximal	-1	no	12.088	11.599	EPSD	TCGA;COSMIC	11.915	Loss
CK1_CK1_CK1-D_CSNK1D_ST	Q9Y6Q9	NCOA3	P48730	CSNK1D	T663	S669C	669	Missense	distal	6	no	12.088	7.101	EPSD	TCGA;ICGC;COSMIC	11.915	Loss
CK1_CK1_CK1-D_CSNK1D_ST	Q9Y6Q9	NCOA3	P48730	CSNK1D	S767	I774S	774	Missense	distal	7	no	12.982	12.755	EPSD	TCGA;ICGC;COSMIC	11.915	Down-regulation
CK1_CK1_CK1-D_CSNK1D_ST	Q9Y6Q9	NCOA3	P48730	CSNK1D	S772	I774S	774	Missense	proximal	2	no	12.752	11.910	EPSD	TCGA;ICGC;COSMIC	11.915	Loss
CK1_CK1_CK1-D_CSNK1D_ST	Q9Y6Q9	NCOA3	P48730	CSNK1D	S857	R854Q	854	Missense	distal	-3	no	13.588	11.568	EPSD	TCGA;ICGC;COSMIC	11.915	Loss
CK1_CK1_CK1-D_CSNK1D_ST	Q9Y6Q9	NCOA3	P48730	CSNK1D	S866	I873M	873	Missense	distal	7	no	10.773	12.132	EPSD	TCGA;ICGC;COSMIC	11.915	Gain
CK1_CK1_CK1-D_CSNK1D_ST	Q9Y6Q9	NCOA3	P48730	CSNK1D	S866	S867G	867	Missense	proximal	1	no	10.773	13.932	EPSD	TCGA;ICGC;COSMIC	11.915	Gain
CK1_CK1_CK1-D_CSNK1D_ST	P30291	WEE1	P48730	CSNK1D	S212	E218K	218	Missense	distal	6	no	17.521	15.723	PhosphoSitePlus	TCGA;ICGC;COSMIC	11.915	Down-regulation
CK1_CK1_CK1-D_CSNK1D_ST	P30291	WEE1	P48730	CSNK1D	S212	L213R	213	Missense	proximal	1	no	17.521	16.591	PhosphoSitePlus	TCGA;ICGC;COSMIC	11.915	Down-regulation
CK1_CK1_CK1-D_CSNK1D_ST	P30291	WEE1	P48730	CSNK1D	S212	V206F	206	Missense	distal	-6	no	17.521	16.947	PhosphoSitePlus	TCGA;ICGC;COSMIC	11.915	Down-regulation
CK1_CK1_CK1-D_CSNK1D_ST	P30291	WEE1	P48730	CSNK1D	T239	P237A	237	Missense	proximal	-2	no	10.909	13.064	EPSD	TCGA;ICGC;COSMIC	11.915	Gain
CK1_CK1_CK1-D_CSNK1D_ST	P30291	WEE1	P48730	CSNK1D	S242	P237A	237	Missense	distal	-5	no	13.310	13.744	EPSD	TCGA;ICGC;COSMIC	11.915	Up-regulation
CK1_CK1_CK1-D_CSNK1D_ST	P30291	WEE1	P48730	CSNK1D	S242	H246Y	246	Missense	distal	4	no	13.310	13.148	EPSD	TCGA;ICGC;COSMIC	11.915	Down-regulation
CK1_CK1_CK1-D_CSNK1D_ST	P30291	WEE1	P48730	CSNK1D	S480	L483F	483	Missense	distal	3	no	11.482	12.111	EPSD	TCGA;ICGC;COSMIC	11.915	Gain
CK1_CK1_CK1-D_CSNK1D_ST	P30291	WEE1	P48730	CSNK1D	S559	H566R	566	Missense	distal	7	no	13.064	10.110	EPSD	TCGA;ICGC;COSMIC	11.915	Loss
Atypical_PDHK_PDHK_PDK4_ST	P29803	PDHA2	Q16654	PDK4	S128	Y123C	123	Missense	distal	-5	no	2.424	2.487	EPSD	TCGA;ICGC;COSMIC	1.272	Up-regulation
Atypical_PDHK_PDHK_PDK4_ST	P29803	PDHA2	Q16654	PDK4	S128	E135Q	135	Missense	distal	7	no	2.424	2.420	EPSD	TCGA;ICGC;COSMIC	1.272	Down-regulation
Atypical_PDHK_PDHK_PDK4_ST	P29803	PDHA2	Q16654	PDK4	T231	G228V	228	Missense	distal	-3	no	1.976	2.043	EPSD	TCGA;ICGC;COSMIC	1.272	Up-regulation
Atypical_PDHK_PDHK_PDK4_ST	P29803	PDHA2	Q16654	PDK4	T231	Y225F	225	Missense	distal	-6	no	1.976	1.679	EPSD	TCGA;ICGC;COSMIC	1.272	Down-regulation
Atypical_PDHK_PDHK_PDK4_ST	P29803	PDHA2	Q16654	PDK4	T231	Y225C	225	Missense	distal	-6	no	1.976	1.679	EPSD	TCGA;ICGC;COSMIC	1.272	Down-regulation
Atypical_PDHK_PDHK_PDK4_ST	P29803	PDHA2	Q16654	PDK4	T231	E232V	232	Missense	proximal	1	no	1.976	2.012	EPSD	TCGA;ICGC;COSMIC	1.272	Up-regulation
Atypical_PDHK_PDHK_PDK4_ST	P29803	PDHA2	Q16654	PDK4	T231	G226R	226	Missense	distal	-5	no	1.976	2.502	EPSD	TCGA;ICGC;COSMIC	1.272	Up-regulation
Atypical_PDHK_PDHK_PDK4_ST	P29803	PDHA2	Q16654	PDK4	T231	R233K	233	Missense	proximal	2	no	1.976	1.839	EPSD	TCGA;ICGC;COSMIC	1.272	Down-regulation
Atypical_PDHK_PDHK_PDK4_ST	P29803	PDHA2	Q16654	PDK4	T284	Y285H	285	Missense	proximal	1	no	2.392	2.114	EPSD	TCGA;ICGC;COSMIC	1.272	Down-regulation
Atypical_PDHK_PDHK_PDK4_ST	P29803	PDHA2	Q16654	PDK4	T284	M280I	280	Missense	distal	-4	no	2.392	2.269	EPSD	TCGA;ICGC;COSMIC	1.272	Down-regulation
Atypical_PDHK_PDHK_PDK4_ST	P29803	PDHA2	Q16654	PDK4	S291	Y285H	285	Missense	distal	-6	no	13.830	13.524	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	1.272	Down-regulation
Atypical_PDHK_PDHK_PDK4_ST	P29803	PDHA2	Q16654	PDK4	S291	M292I	292	Missense	proximal	1	no	13.830	13.733	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	1.272	Down-regulation
Atypical_PDHK_PDHK_PDK4_ST	P29803	PDHA2	Q16654	PDK4	S291	S298C	298	Missense	distal	7	no	13.830	13.808	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	1.272	Down-regulation
Atypical_PDHK_PDHK_PDK4_ST	P29803	PDHA2	Q16654	PDK4	S291	S293T	293	Missense	proximal	2	no	13.830	13.773	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	1.272	Down-regulation
Atypical_PDHK_PDHK_PDK4_ST	P29803	PDHA2	Q16654	PDK4	S298	R300C	300	Missense	proximal	2	no	14.303	14.144	PhosphoSitePlus;EPSD	TCGA;ICGC;COSMIC	1.272	Down-regulation
Atypical_PDHK_PDHK_PDK4_ST	P29803	PDHA2	Q16654	PDK4	S298	R302Q	302	Missense	distal	4	no	14.303	13.911	PhosphoSitePlus;EPSD	TCGA;ICGC;COSMIC	1.272	Down-regulation
Atypical_PDHK_PDHK_PDK4_ST	P29803	PDHA2	Q16654	PDK4	S298	R300H	300	Missense	proximal	2	no	14.303	14.139	PhosphoSitePlus;EPSD	TCGA;ICGC;COSMIC;CCLE	1.272	Down-regulation
Atypical_PDHK_PDHK_PDK4_ST	P29803	PDHA2	Q16654	PDK4	S298	M292I	292	Missense	distal	-6	no	14.303	14.196	PhosphoSitePlus;EPSD	TCGA;ICGC;COSMIC	1.272	Down-regulation
Atypical_PDHK_PDHK_PDK4_ST	P29803	PDHA2	Q16654	PDK4	S298	R300S	300	Missense	proximal	2	no	14.303	14.210	PhosphoSitePlus;EPSD	TCGA;ICGC;COSMIC	1.272	Down-regulation
Atypical_PDHK_PDHK_PDK4_ST	P29803	PDHA2	Q16654	PDK4	S298	R300L	300	Missense	proximal	2	no	14.303	14.155	PhosphoSitePlus;EPSD	TCGA;ICGC;COSMIC	1.272	Down-regulation
Atypical_PDHK_PDHK_PDK4_ST	P29803	PDHA2	Q16654	PDK4	S298	S298C	298	Missense	central	0	yes	14.303	0.000	PhosphoSitePlus;EPSD	TCGA;ICGC;COSMIC	1.272	Loss
Atypical_PDHK_PDHK_PDK4_ST	P29803	PDHA2	Q16654	PDK4	S298	S293T	293	Missense	distal	-5	no	14.303	14.145	PhosphoSitePlus;EPSD	TCGA;ICGC;COSMIC	1.272	Down-regulation
Atypical_PDHK_PDHK_PDK4_ST	P29803	PDHA2	Q16654	PDK4	S310	V308G	308	Missense	proximal	-2	no	0.655	2.789	EPSD	TCGA;ICGC;COSMIC	1.272	Gain
Other_PLK_SAK_PLK4_ST	O00444	PLK4	O00444	PLK4	S22	L17M	17	Missense	distal	-5	no	540.424	540.560	PhosphoSitePlus;EPSD	TCGA;COSMIC	416.076	Up-regulation
Other_PLK_SAK_PLK4_ST	O00444	PLK4	O00444	PLK4	T170	T174N	174	Missense	distal	4	no	531.423	510.038	EPSD;PhosphoSitePlus	TCGA;ICGC	416.076	Down-regulation
Other_PLK_SAK_PLK4_ST	O00444	PLK4	O00444	PLK4	S298	S303I	303	Missense	distal	5	no	437.770	437.954	EPSD	TCGA;ICGC;COSMIC	416.076	Up-regulation
Other_PLK_SAK_PLK4_ST	O00444	PLK4	O00444	PLK4	S298	S301G	301	Missense	distal	3	no	437.770	419.704	EPSD	TCGA;ICGC;COSMIC	416.076	Down-regulation
Other_PLK_SAK_PLK4_ST	O00444	PLK4	O00444	PLK4	S305	R310T	310	Missense	distal	5	no	601.221	600.422	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	416.076	Down-regulation
Other_PLK_SAK_PLK4_ST	O00444	PLK4	O00444	PLK4	S305	S303I	303	Missense	proximal	-2	no	601.221	497.421	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	416.076	Down-regulation
Other_PLK_SAK_PLK4_ST	O00444	PLK4	O00444	PLK4	S305	R310I	310	Missense	distal	5	no	601.221	603.689	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	416.076	Up-regulation
Other_PLK_SAK_PLK4_ST	O00444	PLK4	O00444	PLK4	S305	S301G	301	Missense	distal	-4	no	601.221	541.845	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	416.076	Down-regulation
Other_PLK_SAK_PLK4_ST	O00444	PLK4	O00444	PLK4	S589	V595A	595	Missense	distal	6	no	369.407	484.147	EPSD	TCGA;COSMIC	416.076	Gain
Other_PLK_SAK_PLK4_ST	Q9HC77	CENPJ	O00444	PLK4	S471	I475M	475	Missense	distal	4	no	403.155	429.737	EPSD	TCGA;ICGC	416.076	Gain
Other_PLK_SAK_PLK4_ST	Q9HC77	CENPJ	O00444	PLK4	T545	M546I	546	Missense	proximal	1	no	437.865	472.391	EPSD	TCGA;ICGC;COSMIC	416.076	Up-regulation
Other_PLK_SAK_PLK4_ST	Q9HC77	CENPJ	O00444	PLK4	T545	P541S	541	Missense	distal	-4	no	437.865	545.071	EPSD	TCGA;ICGC;COSMIC	416.076	Up-regulation
Other_PLK_SAK_PLK4_ST	Q9HC77	CENPJ	O00444	PLK4	S589	F590L	590	Missense	proximal	1	no	412.511	427.777	EPSD	TCGA;ICGC	416.076	Gain
Other_PLK_SAK_PLK4_ST	Q9HC77	CENPJ	O00444	PLK4	S595	S589L	589	Missense	distal	-6	no	529.474	530.449	PhosphoSitePlus	TCGA;ICGC;COSMIC	416.076	Up-regulation
Other_PLK_SAK_PLK4_ST	Q9HC77	CENPJ	O00444	PLK4	S595	F590L	590	Missense	distal	-5	no	529.474	529.193	PhosphoSitePlus	TCGA;ICGC	416.076	Down-regulation
Other_PLK_SAK_PLK4_ST	Q9HC77	CENPJ	O00444	PLK4	S660	L667F	667	Missense	distal	7	no	472.220	469.578	EPSD	TCGA;ICGC;COSMIC	416.076	Down-regulation
Other_PLK_SAK_PLK4_ST	Q9HC77	CENPJ	O00444	PLK4	S662	L667F	667	Missense	distal	5	no	423.146	429.183	EPSD	TCGA;ICGC;COSMIC	416.076	Up-regulation
Other_PLK_SAK_PLK4_ST	Q9HC77	CENPJ	O00444	PLK4	S717	R721T	721	Missense	distal	4	no	401.231	432.169	EPSD	TCGA;ICGC;COSMIC	416.076	Gain
Other_PLK_SAK_PLK4_ST	Q9HC77	CENPJ	O00444	PLK4	S1125	P1126S	1126	Missense	proximal	1	no	331.902	476.469	EPSD	TCGA;ICGC;COSMIC	416.076	Gain
Other_PLK_SAK_PLK4_ST	Q969U6	FBXW5	O00444	PLK4	S151	S156L	156	Missense	distal	5	no	614.676	612.346	PhosphoSitePlus	TCGA;ICGC;COSMIC	416.076	Down-regulation
Other_PLK_SAK_PLK4_ST	Q15154	PCM1	O00444	PLK4	S65	P66L	66	Missense	proximal	1	no	260.301	493.238	EPSD	TCGA;ICGC;COSMIC	416.076	Gain
Other_PLK_SAK_PLK4_ST	Q15154	PCM1	O00444	PLK4	S330	G327S	327	Missense	distal	-3	no	415.893	423.608	EPSD	TCGA;ICGC	416.076	Gain
Other_PLK_SAK_PLK4_ST	Q15154	PCM1	O00444	PLK4	S370	R366K	366	Missense	distal	-4	no	467.069	371.762	EPSD	TCGA;ICGC;COSMIC	416.076	Loss
Other_PLK_SAK_PLK4_ST	Q15154	PCM1	O00444	PLK4	S372	R366K	366	Missense	distal	-6	no	751.413	750.760	PhosphoSitePlus	TCGA;ICGC;COSMIC	416.076	Down-regulation
Other_PLK_SAK_PLK4_ST	Q15154	PCM1	O00444	PLK4	S380	K382T	382	Missense	proximal	2	no	389.244	465.715	EPSD	TCGA;ICGC	416.076	Gain
Other_PLK_SAK_PLK4_ST	Q15154	PCM1	O00444	PLK4	T441	Q438H	438	Missense	distal	-3	no	416.129	417.959	EPSD	TCGA;ICGC;COSMIC	416.076	Up-regulation
Other_PLK_SAK_PLK4_ST	Q15154	PCM1	O00444	PLK4	T441	D437N	437	Missense	distal	-4	no	416.129	427.937	EPSD	TCGA;ICGC;COSMIC	416.076	Up-regulation
Other_PLK_SAK_PLK4_ST	Q15154	PCM1	O00444	PLK4	T441	S435G	435	Missense	distal	-6	no	416.129	412.039	EPSD	TCGA;ICGC	416.076	Loss
Other_PLK_SAK_PLK4_ST	Q15154	PCM1	O00444	PLK4	S471	S464C	464	Missense	distal	-7	no	426.015	390.108	EPSD	TCGA;ICGC;COSMIC	416.076	Loss
Other_PLK_SAK_PLK4_ST	Q15154	PCM1	O00444	PLK4	S690	D697N	697	Missense	distal	7	no	425.538	426.651	EPSD	TCGA;ICGC;COSMIC	416.076	Up-regulation
Other_PLK_SAK_PLK4_ST	Q15154	PCM1	O00444	PLK4	S694	D697N	697	Missense	distal	3	no	449.069	443.704	EPSD	TCGA;ICGC;COSMIC	416.076	Down-regulation
Other_PLK_SAK_PLK4_ST	Q15154	PCM1	O00444	PLK4	S1283	Q1285R	1285	Missense	proximal	2	no	385.657	426.343	EPSD	TCGA;ICGC;COSMIC	416.076	Gain
Other_PLK_SAK_PLK4_ST	Q15154	PCM1	O00444	PLK4	S1283	A1284T	1284	Missense	proximal	1	no	385.657	438.395	EPSD	TCGA;ICGC;COSMIC	416.076	Gain
Other_PLK_SAK_PLK4_ST	Q15154	PCM1	O00444	PLK4	S1462	E1458K	1458	Missense	distal	-4	no	419.235	335.304	EPSD	TCGA;ICGC;COSMIC	416.076	Loss
Other_PLK_SAK_PLK4_ST	Q15154	PCM1	O00444	PLK4	S1464	D1470H	1470	Missense	distal	6	no	480.026	474.057	EPSD	TCGA;ICGC;COSMIC	416.076	Down-regulation
Other_PLK_SAK_PLK4_ST	Q15154	PCM1	O00444	PLK4	S1464	E1458K	1458	Missense	distal	-6	no	480.026	479.853	EPSD	TCGA;ICGC;COSMIC	416.076	Down-regulation
Other_PLK_SAK_PLK4_ST	Q15154	PCM1	O00444	PLK4	T1468	D1470H	1470	Missense	proximal	2	no	502.854	484.425	EPSD	TCGA;ICGC;COSMIC	416.076	Down-regulation
Other_PLK_SAK_PLK4_ST	Q15154	PCM1	O00444	PLK4	T1468	K1475N	1475	Missense	distal	7	no	502.854	507.412	EPSD	TCGA;ICGC;COSMIC	416.076	Up-regulation
Other_PLK_SAK_PLK4_ST	Q15154	PCM1	O00444	PLK4	T1472	K1475N	1475	Missense	distal	3	no	402.411	428.629	EPSD	TCGA;ICGC;COSMIC	416.076	Gain
Other_PLK_SAK_PLK4_ST	Q15154	PCM1	O00444	PLK4	T1532	R1529C	1529	Missense	distal	-3	no	437.175	415.785	EPSD	TCGA;COSMIC	416.076	Loss
Other_PLK_SAK_PLK4_ST	Q15154	PCM1	O00444	PLK4	S1786	S1786C	1786	Missense	central	0	yes	499.236	0.000	EPSD	TCGA;COSMIC	416.076	Loss
Other_PLK_SAK_PLK4_ST	Q15154	PCM1	O00444	PLK4	S1786	V1781L	1781	Missense	distal	-5	no	499.236	499.078	EPSD	TCGA;ICGC	416.076	Down-regulation
Other_PLK_SAK_PLK4_ST	Q15154	PCM1	O00444	PLK4	S1786	T1790S	1790	Missense	distal	4	no	499.236	489.102	EPSD	TCGA;COSMIC	416.076	Down-regulation
Other_PLK_SAK_PLK4_ST	Q15468	STIL	O00444	PLK4	T557	S556Y	556	Missense	proximal	-1	no	444.543	429.796	EPSD	TCGA;ICGC	416.076	Down-regulation
Other_PLK_SAK_PLK4_ST	O43303	CCP110	O00444	PLK4	S21	P27S	27	Missense	distal	6	no	381.485	503.063	EPSD	TCGA;ICGC;COSMIC	416.076	Gain
Other_PLK_SAK_PLK4_ST	O43303	CCP110	O00444	PLK4	S24	P27S	27	Missense	distal	3	no	504.720	587.364	EPSD	TCGA;ICGC;COSMIC	416.076	Up-regulation
Other_PLK_SAK_PLK4_ST	O43303	CCP110	O00444	PLK4	S24	L20P	20	Missense	distal	-4	no	504.720	431.492	EPSD	TCGA;ICGC;COSMIC	416.076	Down-regulation
Other_PLK_SAK_PLK4_ST	O43303	CCP110	O00444	PLK4	S98	N96D	96	Missense	proximal	-2	no	526.438	474.184	PhosphoSitePlus	TCGA;ICGC;COSMIC	416.076	Down-regulation
Other_PLK_SAK_PLK4_ST	O43303	CCP110	O00444	PLK4	S98	N96S	96	Missense	proximal	-2	no	526.438	515.957	PhosphoSitePlus	TCGA;ICGC	416.076	Down-regulation
Other_PLK_SAK_PLK4_ST	O43303	CCP110	O00444	PLK4	S98	D99Y	99	Missense	proximal	1	no	526.438	477.308	PhosphoSitePlus	TCGA;ICGC;COSMIC	416.076	Down-regulation
Other_PLK_SAK_PLK4_ST	O43303	CCP110	O00444	PLK4	S247	R246H	246	Missense	proximal	-1	no	464.522	461.480	EPSD	TCGA;ICGC;COSMIC	416.076	Down-regulation
Other_PLK_SAK_PLK4_ST	O43303	CCP110	O00444	PLK4	S247	S247I	247	Missense	central	0	yes	464.522	0.000	EPSD	TCGA;ICGC;COSMIC	416.076	Loss
Other_PLK_SAK_PLK4_ST	O43303	CCP110	O00444	PLK4	S356	I354M	354	Missense	proximal	-2	no	458.797	536.028	EPSD	TCGA;ICGC;COSMIC	416.076	Up-regulation
Other_PLK_SAK_PLK4_ST	O43303	CCP110	O00444	PLK4	S356	S360L	360	Missense	distal	4	no	458.797	446.596	EPSD	TCGA;ICGC;COSMIC	416.076	Down-regulation
Other_PLK_SAK_PLK4_ST	O43303	CCP110	O00444	PLK4	S356	E350K	350	Missense	distal	-6	no	458.797	458.624	EPSD	TCGA;ICGC;COSMIC	416.076	Down-regulation
Other_PLK_SAK_PLK4_ST	O43303	CCP110	O00444	PLK4	S356	K355N	355	Missense	proximal	-1	no	458.797	465.619	EPSD	TCGA;ICGC	416.076	Up-regulation
Other_PLK_SAK_PLK4_ST	O43303	CCP110	O00444	PLK4	T358	I354M	354	Missense	distal	-4	no	487.503	525.354	EPSD	TCGA;ICGC;COSMIC	416.076	Up-regulation
Other_PLK_SAK_PLK4_ST	O43303	CCP110	O00444	PLK4	T358	S360L	360	Missense	proximal	2	no	487.503	518.706	EPSD	TCGA;ICGC;COSMIC	416.076	Up-regulation
Other_PLK_SAK_PLK4_ST	O43303	CCP110	O00444	PLK4	T358	K355N	355	Missense	distal	-3	no	487.503	497.091	EPSD	TCGA;ICGC	416.076	Up-regulation
Other_PLK_SAK_PLK4_ST	O43303	CCP110	O00444	PLK4	T382	R377Q	377	Missense	distal	-5	no	478.780	478.923	EPSD	TCGA;ICGC;COSMIC;GDSC;CCLE	416.076	Up-regulation
Other_PLK_SAK_PLK4_ST	O43303	CCP110	O00444	PLK4	T382	R379H	379	Missense	distal	-3	no	478.780	473.231	EPSD	TCGA;ICGC;GDSC	416.076	Down-regulation
Other_PLK_SAK_PLK4_ST	O43303	CCP110	O00444	PLK4	T382	R379L	379	Missense	distal	-3	no	478.780	484.764	EPSD	TCGA;ICGC;COSMIC	416.076	Up-regulation
Other_PLK_SAK_PLK4_ST	O43303	CCP110	O00444	PLK4	T382	A385V	385	Missense	distal	3	no	478.780	421.587	EPSD	TCGA;ICGC;COSMIC	416.076	Down-regulation
Other_PLK_SAK_PLK4_ST	O43303	CCP110	O00444	PLK4	S918	M925I	925	Missense	distal	7	no	447.637	444.468	EPSD	TCGA;ICGC;COSMIC	416.076	Down-regulation
AGC_DMPK_CRIK_CIT_ST	P24844	MYL9	O14578	CIT	T11	K7R	7	Missense	distal	-4	no	0.458	0.495	EPSD	TCGA;ICGC;COSMIC	0.226	Up-regulation
AGC_DMPK_CRIK_CIT_ST	P24844	MYL9	O14578	CIT	T11	T11I	11	Missense	central	0	yes	0.458	0.000	EPSD	TCGA;ICGC;COSMIC	0.226	Loss
AGC_DMPK_CRIK_CIT_ST	P24844	MYL9	O14578	CIT	T11	R17W	17	Missense	distal	6	no	0.458	0.490	EPSD	TCGA;ICGC;COSMIC	0.226	Up-regulation
AGC_DMPK_CRIK_CIT_ST	P24844	MYL9	O14578	CIT	T11	A6V	6	Missense	distal	-5	no	0.458	0.442	EPSD	TCGA;ICGC	0.226	Down-regulation
AGC_DMPK_CRIK_CIT_ST	P24844	MYL9	O14578	CIT	T19	R17W	17	Missense	proximal	-2	no	6.379	6.350	PhosphoSitePlus;EPSD	TCGA;ICGC;COSMIC	0.226	Down-regulation
AGC_DMPK_CRIK_CIT_ST	P24844	MYL9	O14578	CIT	S20	R17W	17	Missense	distal	-3	no	6.070	6.056	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	0.226	Down-regulation
Other_Aur_AURKC_ST	Q9NQS7	INCENP	Q9UQB9	AURKC	S61	T59I	59	Missense	proximal	-2	no	18.509	14.342	EPSD	TCGA;ICGC;COSMIC	14.093	Down-regulation
Other_Aur_AURKC_ST	Q9NQS7	INCENP	Q9UQB9	AURKC	S72	R69K	69	Missense	distal	-3	no	20.122	19.178	EPSD	TCGA	14.093	Down-regulation
Other_Aur_AURKC_ST	Q9NQS7	INCENP	Q9UQB9	AURKC	S91	R88H	88	Missense	distal	-3	no	19.994	20.057	EPSD	TCGA;ICGC	14.093	Up-regulation
Other_Aur_AURKC_ST	Q9NQS7	INCENP	Q9UQB9	AURKC	S94	R100S	100	Missense	distal	6	no	18.704	19.552	EPSD	TCGA;ICGC;COSMIC	14.093	Up-regulation
Other_Aur_AURKC_ST	Q9NQS7	INCENP	Q9UQB9	AURKC	S94	R88H	88	Missense	distal	-6	no	18.704	18.845	EPSD	TCGA;ICGC	14.093	Up-regulation
Other_Aur_AURKC_ST	Q9NQS7	INCENP	Q9UQB9	AURKC	S142	A137T	137	Missense	distal	-5	no	14.841	14.931	EPSD	TCGA;ICGC;COSMIC	14.093	Up-regulation
Other_Aur_AURKC_ST	Q9NQS7	INCENP	Q9UQB9	AURKC	S142	M136T	136	Missense	distal	-6	no	14.841	14.982	EPSD	TCGA;ICGC;COSMIC	14.093	Up-regulation
Other_Aur_AURKC_ST	Q9NQS7	INCENP	Q9UQB9	AURKC	T184	H182D	182	Missense	proximal	-2	no	19.442	11.332	EPSD	TCGA;ICGC;COSMIC	14.093	Loss
Other_Aur_AURKC_ST	Q9NQS7	INCENP	Q9UQB9	AURKC	T184	S188Y	188	Missense	distal	4	no	19.442	18.194	EPSD	TCGA;ICGC;COSMIC	14.093	Down-regulation
Other_Aur_AURKC_ST	Q9NQS7	INCENP	Q9UQB9	AURKC	T184	P191T	191	Missense	distal	7	no	19.442	19.645	EPSD	TCGA;ICGC	14.093	Up-regulation
Other_Aur_AURKC_ST	Q9NQS7	INCENP	Q9UQB9	AURKC	T184	Q181L	181	Missense	distal	-3	no	19.442	19.110	EPSD	TCGA;ICGC;COSMIC	14.093	Down-regulation
Other_Aur_AURKC_ST	Q9NQS7	INCENP	Q9UQB9	AURKC	T207	P212L	212	Missense	distal	5	no	17.060	17.153	EPSD	TCGA;ICGC	14.093	Up-regulation
Other_Aur_AURKC_ST	Q9NQS7	INCENP	Q9UQB9	AURKC	S269	S263F	263	Missense	distal	-6	no	15.126	15.492	EPSD	TCGA;ICGC;COSMIC	14.093	Up-regulation
Other_Aur_AURKC_ST	Q9NQS7	INCENP	Q9UQB9	AURKC	S269	P270Q	270	Missense	proximal	1	no	15.126	15.646	EPSD	TCGA;ICGC;COSMIC	14.093	Up-regulation
Other_Aur_AURKC_ST	Q9NQS7	INCENP	Q9UQB9	AURKC	S306	Q301E	301	Missense	distal	-5	no	18.471	18.432	EPSD	TCGA;ICGC;COSMIC	14.093	Down-regulation
Other_Aur_AURKC_ST	Q9NQS7	INCENP	Q9UQB9	AURKC	S306	P310S	310	Missense	distal	4	no	18.471	19.420	EPSD	TCGA;ICGC;COSMIC	14.093	Up-regulation
Other_Aur_AURKC_ST	Q9NQS7	INCENP	Q9UQB9	AURKC	S336	T343S	343	Missense	distal	7	no	18.620	18.413	EPSD	TCGA;ICGC;COSMIC	14.093	Down-regulation
Other_Aur_AURKC_ST	Q9NQS7	INCENP	Q9UQB9	AURKC	S336	K342N	342	Missense	distal	6	no	18.620	17.840	EPSD	TCGA;ICGC;COSMIC	14.093	Down-regulation
Other_Aur_AURKC_ST	Q9NQS7	INCENP	Q9UQB9	AURKC	S411	E407K	407	Missense	distal	-4	no	15.627	15.316	EPSD	TCGA;ICGC;COSMIC	14.093	Down-regulation
Other_Aur_AURKC_ST	Q9NQS7	INCENP	Q9UQB9	AURKC	S421	P425L	425	Missense	distal	4	no	16.139	15.713	EPSD	TCGA;ICGC;COSMIC	14.093	Down-regulation
Other_Aur_AURKC_ST	Q9NQS7	INCENP	Q9UQB9	AURKC	S486	L492P	492	Missense	distal	6	no	15.849	18.091	EPSD	TCGA	14.093	Up-regulation
Other_Aur_AURKC_ST	Q9NQS7	INCENP	Q9UQB9	AURKC	S486	P491A	491	Missense	distal	5	no	15.849	15.839	EPSD	TCGA;ICGC;COSMIC	14.093	Down-regulation
Other_Aur_AURKC_ST	Q9NQS7	INCENP	Q9UQB9	AURKC	S486	R490W	490	Missense	distal	4	no	15.849	15.895	EPSD	TCGA;ICGC;COSMIC	14.093	Up-regulation
Other_Aur_AURKC_ST	Q9NQS7	INCENP	Q9UQB9	AURKC	S486	S481L	481	Missense	distal	-5	no	15.849	15.435	EPSD	TCGA;ICGC;COSMIC	14.093	Down-regulation
Other_Aur_AURKC_ST	Q9NQS7	INCENP	Q9UQB9	AURKC	S486	R490Q	490	Missense	distal	4	no	15.849	15.194	EPSD	TCGA;ICGC;COSMIC	14.093	Down-regulation
Other_Aur_AURKC_ST	Q9NQS7	INCENP	Q9UQB9	AURKC	T524	R522C	522	Missense	proximal	-2	no	19.996	12.157	EPSD	TCGA;ICGC;COSMIC	14.093	Loss
Other_Aur_AURKC_ST	Q9NQS7	INCENP	Q9UQB9	AURKC	T524	R522H	522	Missense	proximal	-2	no	19.996	19.998	EPSD	TCGA;ICGC	14.093	Up-regulation
Other_Aur_AURKC_ST	Q9NQS7	INCENP	Q9UQB9	AURKC	T524	R527H	527	Missense	distal	3	no	19.996	19.847	EPSD	TCGA;ICGC;CCLE	14.093	Down-regulation
Other_Aur_AURKC_ST	Q9NQS7	INCENP	Q9UQB9	AURKC	T892	S894F	894	Missense	proximal	2	no	30.253	31.161	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	14.093	Up-regulation
Other_Aur_AURKC_ST	Q9NQS7	INCENP	Q9UQB9	AURKC	S893	S894F	894	Missense	proximal	1	no	32.340	30.261	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	14.093	Down-regulation
Other_Aur_AURKC_ST	Q9NQS7	INCENP	Q9UQB9	AURKC	S893	P900L	900	Missense	distal	7	no	32.340	32.687	EPSD;PhosphoSitePlus	TCGA;ICGC	14.093	Up-regulation
Other_Aur_AURKC_ST	Q9NQS7	INCENP	Q9UQB9	AURKC	S894	S894F	894	Missense	central	0	yes	30.434	0.000	PhosphoSitePlus;EPSD	TCGA;ICGC;COSMIC	14.093	Loss
Other_Aur_AURKC_ST	Q9NQS7	INCENP	Q9UQB9	AURKC	S894	P900L	900	Missense	distal	6	no	30.434	28.191	PhosphoSitePlus;EPSD	TCGA;ICGC	14.093	Down-regulation
Other_Aur_AURKC_ST	O15392	BIRC5	Q9UQB9	AURKC	S20	P26S	26	Missense	distal	6	no	28.038	27.573	PhosphoSitePlus	TCGA;ICGC;COSMIC	14.093	Down-regulation
Other_Aur_AURKC_ST	O15392	BIRC5	Q9UQB9	AURKC	S20	F13S	13	Missense	distal	-7	no	28.038	27.497	PhosphoSitePlus	TCGA;ICGC	14.093	Down-regulation
Other_Aur_AURKC_ST	O75410	TACC1	Q9UQB9	AURKC	S91	S94L	94	Missense	distal	3	no	15.108	15.884	EPSD	TCGA;ICGC;COSMIC	14.093	Up-regulation
Other_Aur_AURKC_ST	O75410	TACC1	Q9UQB9	AURKC	S91	A97T	97	Missense	distal	6	no	15.108	15.135	EPSD	TCGA;ICGC;COSMIC	14.093	Up-regulation
Other_Aur_AURKC_ST	O75410	TACC1	Q9UQB9	AURKC	S315	S313L	313	Missense	proximal	-2	no	14.898	10.184	EPSD	TCGA;ICGC;COSMIC	14.093	Loss
Other_Aur_AURKC_ST	O75410	TACC1	Q9UQB9	AURKC	S361	G357C	357	Missense	distal	-4	no	14.188	14.090	EPSD	TCGA;ICGC;COSMIC	14.093	Loss
Other_Aur_AURKC_ST	O75410	TACC1	Q9UQB9	AURKC	T504	G501D	501	Missense	distal	-3	no	14.606	13.868	EPSD	TCGA;COSMIC	14.093	Loss
Other_Aur_AURKC_ST	O75410	TACC1	Q9UQB9	AURKC	T504	E507Q	507	Missense	distal	3	no	14.606	14.773	EPSD	TCGA;COSMIC	14.093	Up-regulation
Other_Aur_AURKC_ST	O75410	TACC1	Q9UQB9	AURKC	S759	R752Q	752	Missense	distal	-7	no	15.038	15.502	EPSD	TCGA;COSMIC	14.093	Up-regulation
Other_Aur_AURKC_ST	O75410	TACC1	Q9UQB9	AURKC	S759	A764D	764	Missense	distal	5	no	15.038	15.123	EPSD	TCGA;COSMIC	14.093	Up-regulation
Other_Aur_AURKC_ST	O75410	TACC1	Q9UQB9	AURKC	S759	H763Y	763	Missense	distal	4	no	15.038	14.732	EPSD	TCGA;COSMIC	14.093	Down-regulation
Other_Aur_AURKC_ST	O75410	TACC1	Q9UQB9	AURKC	S759	K756E	756	Missense	distal	-3	no	15.038	14.443	EPSD	TCGA;GDSC	14.093	Down-regulation
Other_Aur_AURKC_ST	P25963	NFKBIA	Q9UQB9	AURKC	S32	D31N	31	Missense	proximal	-1	no	31.679	32.149	PhosphoSitePlus	TCGA;ICGC;COSMIC	14.093	Up-regulation
Other_Aur_AURKC_ST	P25963	NFKBIA	Q9UQB9	AURKC	S32	D27H	27	Missense	distal	-5	no	31.679	31.838	PhosphoSitePlus	TCGA;ICGC;COSMIC	14.093	Up-regulation
STE_STE7_MEK7_MAP2K7_ST	P45984	MAPK9	O14733	MAP2K7	T183	A176V	176	Missense	distal	-7	no	8.801	8.759	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	2.107	Down-regulation
STE_STE7_MEK7_MAP2K7_ST	P45984	MAPK9	O14733	MAP2K7	T183	C177Y	177	Missense	distal	-6	no	8.801	8.630	EPSD;PhosphoSitePlus	TCGA;ICGC	2.107	Down-regulation
STE_STE7_MEK7_MAP2K7_ST	P45984	MAPK9	O14733	MAP2K7	T183	M181I	181	Missense	proximal	-2	no	8.801	8.668	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	2.107	Down-regulation
STE_STE7_MEK7_MAP2K7_ST	P45984	MAPK9	O14733	MAP2K7	T183	T183A	183	Missense	central	0	yes	8.801	0.000	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	2.107	Loss
STE_STE7_MEK7_MAP2K7_ST	P45984	MAPK9	O14733	MAP2K7	S390	S397L	397	Missense	distal	7	no	2.742	2.695	EPSD	TCGA;ICGC;COSMIC	2.107	Down-regulation
STE_STE7_MEK7_MAP2K7_ST	P45984	MAPK9	O14733	MAP2K7	S390	S392L	392	Missense	proximal	2	no	2.742	2.677	EPSD	TCGA;ICGC;COSMIC;GDSC;CCLE	2.107	Down-regulation
STE_STE7_MEK7_MAP2K7_ST	P45984	MAPK9	O14733	MAP2K7	T404	S397L	397	Missense	distal	-7	no	6.076	5.974	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	2.107	Down-regulation
STE_STE7_MEK7_MAP2K7_ST	P45984	MAPK9	O14733	MAP2K7	T404	D410Y	410	Missense	distal	6	no	6.076	5.967	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	2.107	Down-regulation
STE_STE7_MEK7_MAP2K7_ST	P45984	MAPK9	O14733	MAP2K7	T404	T404M	404	Missense	central	0	yes	6.076	0.000	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	2.107	Loss
STE_STE7_MEK7_MAP2K7_ST	P45984	MAPK9	O14733	MAP2K7	S407	L413I	413	Missense	distal	6	no	5.531	5.429	PhosphoSitePlus;EPSD	TCGA;ICGC	2.107	Down-regulation
STE_STE7_MEK7_MAP2K7_ST	P45984	MAPK9	O14733	MAP2K7	S407	D410Y	410	Missense	distal	3	no	5.531	5.305	PhosphoSitePlus;EPSD	TCGA;ICGC;COSMIC	2.107	Down-regulation
STE_STE7_MEK7_MAP2K7_ST	P45984	MAPK9	O14733	MAP2K7	S407	T404M	404	Missense	distal	-3	no	5.531	5.571	PhosphoSitePlus;EPSD	TCGA;ICGC;COSMIC	2.107	Up-regulation
STE_STE7_MEK7_MAP2K7_ST	P53779	MAPK10	O14733	MAP2K7	T216	R212S	212	Missense	distal	-4	no	1.801	2.124	EPSD	TCGA;COSMIC	2.107	Gain
STE_STE7_MEK7_MAP2K7_ST	P53779	MAPK10	O14733	MAP2K7	T221	R227H	227	Missense	distal	6	no	9.126	9.099	PhosphoSitePlus	TCGA;COSMIC	2.107	Down-regulation
STE_STE7_MEK7_MAP2K7_ST	P53779	MAPK10	O14733	MAP2K7	T221	M219I	219	Missense	proximal	-2	no	9.126	8.993	PhosphoSitePlus	TCGA;COSMIC	2.107	Down-regulation
STE_STE7_MEK7_MAP2K7_ST	P53779	MAPK10	O14733	MAP2K7	T221	G215S	215	Missense	distal	-6	no	9.126	8.907	PhosphoSitePlus	TCGA;COSMIC	2.107	Down-regulation
STE_STE7_MEK7_MAP2K7_ST	P45983	MAPK8	O14733	MAP2K7	S179	T178M	178	Missense	proximal	-1	no	0.724	2.176	EPSD	TCGA;ICGC;COSMIC	2.107	Gain
STE_STE7_MEK7_MAP2K7_ST	P45983	MAPK8	O14733	MAP2K7	T183	T178M	178	Missense	distal	-5	no	9.246	9.300	PhosphoSitePlus;EPSD	TCGA;ICGC;COSMIC	2.107	Up-regulation
STE_STE7_MEK7_MAP2K7_ST	P45983	MAPK8	O14733	MAP2K7	T183	P184L	184	Missense	proximal	1	no	9.246	8.913	PhosphoSitePlus;EPSD	TCGA;ICGC;COSMIC	2.107	Down-regulation
STE_STE7_MEK7_MAP2K7_ST	P45983	MAPK8	O14733	MAP2K7	T183	R189C	189	Missense	distal	6	no	9.246	9.203	PhosphoSitePlus;EPSD	TCGA;ICGC;COSMIC	2.107	Down-regulation
STE_STE7_MEK7_MAP2K7_ST	P45983	MAPK8	O14733	MAP2K7	T183	R189L	189	Missense	distal	6	no	9.246	9.317	PhosphoSitePlus;EPSD	TCGA;ICGC;COSMIC	2.107	Up-regulation
STE_STE7_MEK7_MAP2K7_ST	P45983	MAPK8	O14733	MAP2K7	T183	R189H	189	Missense	distal	6	no	9.246	9.219	PhosphoSitePlus;EPSD	TCGA;ICGC;COSMIC	2.107	Down-regulation
STE_STE7_MEK7_MAP2K7_ST	Q13158	FADD	O14733	MAP2K7	S194	P195L	195	Missense	proximal	1	no	5.970	5.638	PhosphoSitePlus	TCGA;COSMIC	2.107	Down-regulation
STE_STE7_MEK7_MAP2K7_ST	Q13158	FADD	O14733	MAP2K7	S194	N188Y	188	Missense	distal	-6	no	5.970	6.002	PhosphoSitePlus	TCGA;ICGC;COSMIC	2.107	Up-regulation
STE_STE7_MEK7_MAP2K7_ST	Q13158	FADD	O14733	MAP2K7	S197	P195L	195	Missense	proximal	-2	no	2.596	2.625	EPSD	TCGA;COSMIC	2.107	Up-regulation
TK_Src_Frk_FRK_Y	P60484	PTEN	P42685	FRK	Y155	L152P	152	Missense	distal	-3	no	2.445	2.910	EPSD	TCGA;ICGC;COSMIC;GDSC;CCLE	2.774	Gain
TK_Src_Frk_FRK_Y	P60484	PTEN	P42685	FRK	Y336	R335P	335	Missense	proximal	-1	no	10.404	10.300	PhosphoSitePlus	TCGA;ICGC;COSMIC	2.774	Down-regulation
TK_Src_Frk_FRK_Y	P60484	PTEN	P42685	FRK	Y336	F341V	341	Missense	distal	5	no	10.404	10.415	PhosphoSitePlus	TCGA;ICGC;COSMIC;GDSC;CCLE	2.774	Up-regulation
TK_Src_Frk_FRK_Y	P60484	PTEN	P42685	FRK	Y336	K342N	342	Missense	distal	6	no	10.404	10.383	PhosphoSitePlus	TCGA;ICGC;COSMIC	2.774	Down-regulation
TK_Src_Frk_FRK_Y	P60484	PTEN	P42685	FRK	Y336	F337I	337	Missense	proximal	1	no	10.404	10.053	PhosphoSitePlus	TCGA;ICGC;COSMIC	2.774	Down-regulation
TK_Src_Frk_FRK_Y	P60484	PTEN	P42685	FRK	Y336	F341C	341	Missense	distal	5	no	10.404	10.372	PhosphoSitePlus	TCGA;ICGC;COSMIC	2.774	Down-regulation
Other_NAK_MPSK_STK16_ST	O75716	STK16	O75716	STK16	T185	S180F	180	Missense	distal	-5	no	3.433	3.430	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	1.527	Down-regulation
Other_NAK_MPSK_STK16_ST	O75716	STK16	O75716	STK16	S197	R193Q	193	Missense	distal	-4	no	3.400	3.391	PhosphoSitePlus;EPSD	TCGA;ICGC;COSMIC	1.527	Down-regulation
Other_NAK_MPSK_STK16_ST	O75716	STK16	O75716	STK16	S197	C194R	194	Missense	distal	-3	no	3.400	3.407	PhosphoSitePlus;EPSD	TCGA;ICGC;COSMIC	1.527	Up-regulation
Other_NAK_MPSK_STK16_ST	O75716	STK16	O75716	STK16	S197	R193W	193	Missense	distal	-4	no	3.400	3.391	PhosphoSitePlus;EPSD	TCGA;ICGC;COSMIC	1.527	Down-regulation
Other_NAK_MPSK_STK16_ST	Q9Y295	DRG1	O75716	STK16	T100	I106M	106	Missense	distal	6	no	3.396	3.412	EPSD	TCGA;ICGC;COSMIC	1.527	Up-regulation
Other_NAK_MPSK_STK16_ST	Q9Y295	DRG1	O75716	STK16	T101	I106M	106	Missense	distal	5	no	3.377	3.304	PhosphoSitePlus	TCGA;ICGC;COSMIC	1.527	Down-regulation
TK_EGFR_ERBB2_Y	O43157	PLXNB1	P04626	ERBB2	Y1708	V1703L	1703	Missense	distal	-5	no	6.099	5.836	PhosphoSitePlus;EPSD	TCGA;COSMIC	2.878	Down-regulation
TK_EGFR_ERBB2_Y	O43157	PLXNB1	P04626	ERBB2	Y1708	S1702F	1702	Missense	distal	-6	no	6.099	5.682	PhosphoSitePlus;EPSD	TCGA;COSMIC;GDSC;CCLE	2.878	Down-regulation
TK_EGFR_ERBB2_Y	O43157	PLXNB1	P04626	ERBB2	Y1732	D1736N	1736	Missense	distal	4	no	5.600	5.501	EPSD;PhosphoSitePlus	TCGA;COSMIC	2.878	Down-regulation
TK_EGFR_ERBB2_Y	P04626	ERBB2	P04626	ERBB2	Y877	D873N	873	Missense	distal	-4	no	5.903	5.898	EPSD;PhosphoSitePlus	TCGA;COSMIC	2.878	Down-regulation
TK_EGFR_ERBB2_Y	P04626	ERBB2	P04626	ERBB2	Y1023	E1021Q	1021	Missense	proximal	-2	no	5.878	5.896	EPSD;PhosphoSitePlus	TCGA;COSMIC	2.878	Up-regulation
TK_EGFR_ERBB2_Y	P04626	ERBB2	P04626	ERBB2	Y1112	R1111W	1111	Missense	proximal	-1	no	5.879	5.435	EPSD;PhosphoSitePlus	TCGA;COSMIC	2.878	Down-regulation
TK_EGFR_ERBB2_Y	P04626	ERBB2	P04626	ERBB2	Y1139	R1146Q	1146	Missense	distal	7	no	7.850	7.834	EPSD;PhosphoSitePlus	TCGA;COSMIC	2.878	Down-regulation
TK_EGFR_ERBB2_Y	P04626	ERBB2	P04626	ERBB2	Y1196	P1199T	1199	Missense	distal	3	no	6.266	6.415	EPSD;PhosphoSitePlus	TCGA;COSMIC	2.878	Up-regulation
TK_EGFR_ERBB2_Y	P04626	ERBB2	P04626	ERBB2	Y1221	N1219S	1219	Missense	proximal	-2	no	7.240	7.508	EPSD;PhosphoSitePlus	TCGA;COSMIC	2.878	Up-regulation
TK_EGFR_ERBB2_Y	P04626	ERBB2	P04626	ERBB2	Y1221	S1214N	1214	Missense	distal	-7	no	7.240	7.138	EPSD;PhosphoSitePlus	TCGA;COSMIC;CCLE	2.878	Down-regulation
TK_EGFR_ERBB2_Y	P04626	ERBB2	P04626	ERBB2	Y1222	N1219S	1219	Missense	distal	-3	no	7.251	7.049	PhosphoSitePlus;EPSD	TCGA;COSMIC	2.878	Down-regulation
TK_EGFR_ERBB2_Y	P35222	CTNNB1	P04626	ERBB2	Y30	S37F	37	Missense	distal	7	no	2.709	2.999	EPSD	TCGA;COSMIC;GDSC;CCLE	2.878	Gain
TK_EGFR_ERBB2_Y	P35222	CTNNB1	P04626	ERBB2	Y30	S33F	33	Missense	distal	3	no	2.709	2.890	EPSD	TCGA;COSMIC;GDSC;CCLE	2.878	Gain
TK_EGFR_ERBB2_Y	P35222	CTNNB1	P04626	ERBB2	Y30	S33Y	33	Missense	distal	3	no	2.709	2.907	EPSD	TCGA;COSMIC;GDSC;CCLE	2.878	Gain
TK_EGFR_ERBB2_Y	P35222	CTNNB1	P04626	ERBB2	Y654	E649Q	649	Missense	distal	-5	no	6.363	6.417	PhosphoSitePlus	TCGA;COSMIC	2.878	Up-regulation
TK_EGFR_ERBB2_Y	P35222	CTNNB1	P04626	ERBB2	Y654	T653K	653	Missense	proximal	-1	no	6.363	6.519	PhosphoSitePlus	TCGA;COSMIC	2.878	Up-regulation
TK_EGFR_ERBB2_Y	P35222	CTNNB1	P04626	ERBB2	Y716	R717H	717	Missense	proximal	1	no	2.749	3.129	EPSD	TCGA;COSMIC	2.878	Gain
TK_EGFR_ERBB2_Y	P06493	CDK1	P04626	ERBB2	Y15	K9R	9	Missense	distal	-6	no	4.825	4.859	PhosphoSitePlus	TCGA;ICGC;COSMIC	2.878	Up-regulation
AGC_DMPK_GEK_CDC42BPA_ST	Q5VT25	CDC42BPA	Q5VT25	CDC42BPA	S222	R216P	216	Missense	distal	-6	no	5.515	5.489	EPSD	TCGA;ICGC;COSMIC	2.124	Down-regulation
AGC_DMPK_GEK_CDC42BPA_ST	Q5VT25	CDC42BPA	Q5VT25	CDC42BPA	S222	L224V	224	Missense	proximal	2	no	5.515	5.688	EPSD	TCGA;ICGC;COSMIC	2.124	Up-regulation
AGC_DMPK_GEK_CDC42BPA_ST	Q5VT25	CDC42BPA	Q5VT25	CDC42BPA	S222	L226V	226	Missense	distal	4	no	5.515	5.604	EPSD	TCGA;ICGC;COSMIC	2.124	Up-regulation
AGC_DMPK_GEK_CDC42BPA_ST	Q5VT25	CDC42BPA	Q5VT25	CDC42BPA	S222	E228K	228	Missense	distal	6	no	5.515	5.523	EPSD	TCGA;ICGC;COSMIC	2.124	Up-regulation
AGC_DMPK_GEK_CDC42BPA_ST	Q5VT25	CDC42BPA	Q5VT25	CDC42BPA	S234	T231K	231	Missense	distal	-3	no	5.474	5.439	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	2.124	Down-regulation
AGC_DMPK_GEK_CDC42BPA_ST	Q5VT25	CDC42BPA	Q5VT25	CDC42BPA	S234	E228K	228	Missense	distal	-6	no	5.474	5.456	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	2.124	Down-regulation
AGC_DMPK_GEK_CDC42BPA_ST	Q5VT25	CDC42BPA	Q5VT25	CDC42BPA	T240	D242Y	242	Missense	proximal	2	no	5.481	5.319	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	2.124	Down-regulation
AGC_DMPK_GEK_CDC42BPA_ST	Q5VT25	CDC42BPA	Q5VT25	CDC42BPA	T240	I244N	244	Missense	distal	4	no	5.481	5.499	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	2.124	Up-regulation
AGC_DMPK_GEK_CDC42BPA_ST	Q5VT25	CDC42BPA	Q5VT25	CDC42BPA	S465	E464A	464	Missense	proximal	-1	no	2.074	2.151	EPSD	TCGA;ICGC;COSMIC	2.124	Gain
AGC_DMPK_GEK_CDC42BPA_ST	Q5VT25	CDC42BPA	Q5VT25	CDC42BPA	S1654	S1651F	1651	Missense	distal	-3	no	3.012	2.945	EPSD	TCGA;COSMIC	2.124	Down-regulation
AGC_DMPK_GEK_CDC42BPA_ST	P24844	MYL9	Q5VT25	CDC42BPA	S20	R17W	17	Missense	distal	-3	no	5.235	5.229	PhosphoSitePlus	TCGA;ICGC;COSMIC	2.124	Down-regulation
AGC_DMPK_GEK_CDC42BPA_ST	P24844	MYL9	Q5VT25	CDC42BPA	T97	R104C	104	Missense	distal	7	no	2.207	2.114	EPSD	TCGA;ICGC	2.124	Loss
AGC_DMPK_GEK_CDC42BPA_ST	P24844	MYL9	Q5VT25	CDC42BPA	T97	K93T	93	Missense	distal	-4	no	2.207	1.859	EPSD	TCGA;ICGC;COSMIC	2.124	Loss
AGC_DMPK_GEK_CDC42BPA_ST	P24844	MYL9	Q5VT25	CDC42BPA	T135	E137K	137	Missense	proximal	2	no	2.231	2.390	EPSD	TCGA;COSMIC	2.124	Up-regulation
AGC_DMPK_GEK_CDC42BPA_ST	P24844	MYL9	Q5VT25	CDC42BPA	T135	R133H	133	Missense	proximal	-2	no	2.231	1.921	EPSD	TCGA;COSMIC	2.124	Loss
AGC_DMPK_GEK_CDC42BPA_ST	P24844	MYL9	Q5VT25	CDC42BPA	T135	M130V	130	Missense	distal	-5	no	2.231	2.439	EPSD	TCGA;ICGC;COSMIC;CCLE	2.124	Up-regulation
AGC_DMPK_GEK_CDC42BPA_ST	P24844	MYL9	Q5VT25	CDC42BPA	T135	T129I	129	Missense	distal	-6	no	2.231	2.120	EPSD	TCGA;ICGC;COSMIC	2.124	Loss
AGC_DMPK_GEK_CDC42BPA_ST	P24844	MYL9	Q5VT25	CDC42BPA	T135	E137D	137	Missense	proximal	2	no	2.231	2.253	EPSD	TCGA	2.124	Up-regulation
STE_STE20_FRAY_OXSR1_ST	Q13621	SLC12A1	O95747	OXSR1	S91	A84T	84	Missense	distal	-7	no	24.831	24.839	EPSD	TCGA;ICGC;COSMIC	17.710	Up-regulation
STE_STE20_FRAY_OXSR1_ST	Q13621	SLC12A1	O95747	OXSR1	T95	F101C	101	Missense	distal	6	no	50.566	50.899	EPSD;PhosphoSitePlus	TCGA;ICGC	17.710	Up-regulation
STE_STE20_FRAY_OXSR1_ST	Q13621	SLC12A1	O95747	OXSR1	T100	D107N	107	Missense	distal	7	no	44.600	44.368	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	17.710	Down-regulation
STE_STE20_FRAY_OXSR1_ST	Q13621	SLC12A1	O95747	OXSR1	T100	N104K	104	Missense	distal	4	no	44.600	44.735	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	17.710	Up-regulation
STE_STE20_FRAY_OXSR1_ST	Q13621	SLC12A1	O95747	OXSR1	T100	F101C	101	Missense	proximal	1	no	44.600	42.971	EPSD;PhosphoSitePlus	TCGA;ICGC	17.710	Down-regulation
STE_STE20_FRAY_OXSR1_ST	Q13621	SLC12A1	O95747	OXSR1	T105	V109I	109	Missense	distal	4	no	50.424	50.527	PhosphoSitePlus;EPSD	TCGA;ICGC;COSMIC	17.710	Up-regulation
STE_STE20_FRAY_OXSR1_ST	Q13621	SLC12A1	O95747	OXSR1	T105	D107N	107	Missense	proximal	2	no	50.424	52.032	PhosphoSitePlus;EPSD	TCGA;ICGC;COSMIC	17.710	Up-regulation
STE_STE20_FRAY_OXSR1_ST	Q13621	SLC12A1	O95747	OXSR1	T105	N104K	104	Missense	proximal	-1	no	50.424	45.370	PhosphoSitePlus;EPSD	TCGA;ICGC;COSMIC	17.710	Down-regulation
STE_STE20_FRAY_OXSR1_ST	Q13621	SLC12A1	O95747	OXSR1	T105	F101C	101	Missense	distal	-4	no	50.424	49.588	PhosphoSitePlus;EPSD	TCGA;ICGC	17.710	Down-regulation
STE_STE20_FRAY_OXSR1_ST	Q13621	SLC12A1	O95747	OXSR1	T105	K111R	111	Missense	distal	6	no	50.424	49.896	PhosphoSitePlus;EPSD	TCGA;ICGC;COSMIC	17.710	Down-regulation
STE_STE20_FRAY_OXSR1_ST	Q13621	SLC12A1	O95747	OXSR1	T105	A108V	108	Missense	distal	3	no	50.424	51.196	PhosphoSitePlus;EPSD	TCGA;ICGC;COSMIC	17.710	Up-regulation
STE_STE20_FRAY_OXSR1_ST	Q13621	SLC12A1	O95747	OXSR1	T105	K111N	111	Missense	distal	6	no	50.424	50.645	PhosphoSitePlus;EPSD	TCGA;ICGC;COSMIC	17.710	Up-regulation
STE_STE20_FRAY_OXSR1_ST	Q13621	SLC12A1	O95747	OXSR1	T118	R116C	116	Missense	proximal	-2	no	46.996	45.492	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	17.710	Down-regulation
STE_STE20_FRAY_OXSR1_ST	Q13621	SLC12A1	O95747	OXSR1	T118	P124H	124	Missense	distal	6	no	46.996	46.301	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	17.710	Down-regulation
STE_STE20_FRAY_OXSR1_ST	Q13621	SLC12A1	O95747	OXSR1	T118	S120N	120	Missense	proximal	2	no	46.996	46.064	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	17.710	Down-regulation
STE_STE20_FRAY_OXSR1_ST	Q13621	SLC12A1	O95747	OXSR1	T118	T118I	118	Missense	central	0	yes	46.996	0.000	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	17.710	Loss
STE_STE20_FRAY_OXSR1_ST	Q13621	SLC12A1	O95747	OXSR1	T118	K111R	111	Missense	distal	-7	no	46.996	47.001	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	17.710	Up-regulation
STE_STE20_FRAY_OXSR1_ST	Q13621	SLC12A1	O95747	OXSR1	T118	K111N	111	Missense	distal	-7	no	46.996	46.999	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	17.710	Up-regulation
STE_STE20_FRAY_OXSR1_ST	Q13621	SLC12A1	O95747	OXSR1	S120	R116C	116	Missense	distal	-4	no	46.596	46.241	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	17.710	Down-regulation
STE_STE20_FRAY_OXSR1_ST	Q13621	SLC12A1	O95747	OXSR1	S120	P124H	124	Missense	distal	4	no	46.596	46.300	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	17.710	Down-regulation
STE_STE20_FRAY_OXSR1_ST	Q13621	SLC12A1	O95747	OXSR1	S120	S120N	120	Missense	central	0	yes	46.596	0.000	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	17.710	Loss
STE_STE20_FRAY_OXSR1_ST	Q13621	SLC12A1	O95747	OXSR1	S120	T118I	118	Missense	proximal	-2	no	46.596	43.242	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	17.710	Down-regulation
STE_STE20_FRAY_OXSR1_ST	Q13621	SLC12A1	O95747	OXSR1	S122	R116C	116	Missense	distal	-6	no	19.343	18.895	EPSD	TCGA;ICGC;COSMIC	17.710	Down-regulation
STE_STE20_FRAY_OXSR1_ST	Q13621	SLC12A1	O95747	OXSR1	S122	P124H	124	Missense	proximal	2	no	19.343	23.762	EPSD	TCGA;ICGC;COSMIC	17.710	Up-regulation
STE_STE20_FRAY_OXSR1_ST	Q13621	SLC12A1	O95747	OXSR1	S122	R128Q	128	Missense	distal	6	no	19.343	19.782	EPSD	TCGA;ICGC;COSMIC	17.710	Up-regulation
STE_STE20_FRAY_OXSR1_ST	Q13621	SLC12A1	O95747	OXSR1	S122	S120N	120	Missense	proximal	-2	no	19.343	19.867	EPSD	TCGA;ICGC;COSMIC	17.710	Up-regulation
STE_STE20_FRAY_OXSR1_ST	Q13621	SLC12A1	O95747	OXSR1	S122	T118I	118	Missense	distal	-4	no	19.343	17.497	EPSD	TCGA;ICGC;COSMIC	17.710	Loss
STE_STE20_FRAY_OXSR1_ST	Q13621	SLC12A1	O95747	OXSR1	T882	H887Y	887	Missense	distal	5	no	26.055	26.076	EPSD	TCGA;ICGC;COSMIC	17.710	Up-regulation
STE_STE20_FRAY_OXSR1_ST	Q13621	SLC12A1	O95747	OXSR1	T882	V888A	888	Missense	distal	6	no	26.055	25.436	EPSD	TCGA;ICGC	17.710	Down-regulation
STE_STE20_FRAY_OXSR1_ST	Q13621	SLC12A1	O95747	OXSR1	S885	H887Y	887	Missense	proximal	2	no	18.307	16.860	EPSD	TCGA;ICGC;COSMIC	17.710	Loss
STE_STE20_FRAY_OXSR1_ST	Q13621	SLC12A1	O95747	OXSR1	S885	V888A	888	Missense	distal	3	no	18.307	17.536	EPSD	TCGA;ICGC	17.710	Loss
STE_STE20_FRAY_OXSR1_ST	P55011	SLC12A2	O95747	OXSR1	T964	D961Y	961	Missense	distal	-3	no	7.878	19.446	EPSD	TCGA;ICGC;COSMIC	17.710	Gain
STE_STE20_FRAY_OXSR1_ST	P55017	SLC12A3	O95747	OXSR1	T46	P42L	42	Missense	distal	-4	no	45.760	43.659	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	17.710	Down-regulation
STE_STE20_FRAY_OXSR1_ST	P55017	SLC12A3	O95747	OXSR1	T46	T50A	50	Missense	distal	4	no	45.760	45.813	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	17.710	Up-regulation
STE_STE20_FRAY_OXSR1_ST	P55017	SLC12A3	O95747	OXSR1	T50	R54C	54	Missense	distal	4	no	27.861	28.093	EPSD	TCGA;ICGC;COSMIC	17.710	Up-regulation
STE_STE20_FRAY_OXSR1_ST	P55017	SLC12A3	O95747	OXSR1	T50	T50A	50	Missense	central	0	yes	27.861	0.000	EPSD	TCGA;ICGC;COSMIC	17.710	Loss
STE_STE20_FRAY_OXSR1_ST	P55017	SLC12A3	O95747	OXSR1	T55	R54C	54	Missense	proximal	-1	no	45.147	41.310	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	17.710	Down-regulation
STE_STE20_FRAY_OXSR1_ST	P55017	SLC12A3	O95747	OXSR1	T55	T50A	50	Missense	distal	-5	no	45.147	40.047	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	17.710	Down-regulation
STE_STE20_FRAY_OXSR1_ST	P55017	SLC12A3	O95747	OXSR1	T55	D62N	62	Missense	distal	7	no	45.147	44.915	EPSD;PhosphoSitePlus	TCGA;ICGC	17.710	Down-regulation
STE_STE20_FRAY_OXSR1_ST	P55017	SLC12A3	O95747	OXSR1	T60	R54C	54	Missense	distal	-6	no	53.253	52.805	PhosphoSitePlus;EPSD	TCGA;ICGC;COSMIC	17.710	Down-regulation
STE_STE20_FRAY_OXSR1_ST	P55017	SLC12A3	O95747	OXSR1	T60	V63L	63	Missense	distal	3	no	53.253	53.183	PhosphoSitePlus;EPSD	TCGA;ICGC;COSMIC	17.710	Down-regulation
STE_STE20_FRAY_OXSR1_ST	P55017	SLC12A3	O95747	OXSR1	T60	D62N	62	Missense	proximal	2	no	53.253	54.860	PhosphoSitePlus;EPSD	TCGA;ICGC	17.710	Up-regulation
STE_STE20_FRAY_OXSR1_ST	P55017	SLC12A3	O95747	OXSR1	T66	E68Q	68	Missense	proximal	2	no	20.194	19.724	EPSD	TCGA	17.710	Down-regulation
STE_STE20_FRAY_OXSR1_ST	P55017	SLC12A3	O95747	OXSR1	T66	V63L	63	Missense	distal	-3	no	20.194	18.265	EPSD	TCGA;ICGC;COSMIC	17.710	Down-regulation
STE_STE20_FRAY_OXSR1_ST	P55017	SLC12A3	O95747	OXSR1	T66	E68K	68	Missense	proximal	2	no	20.194	19.115	EPSD	TCGA;ICGC;COSMIC	17.710	Down-regulation
STE_STE20_FRAY_OXSR1_ST	P55017	SLC12A3	O95747	OXSR1	T66	D62N	62	Missense	distal	-4	no	20.194	20.906	EPSD	TCGA;ICGC	17.710	Up-regulation
STE_STE20_FRAY_OXSR1_ST	P55017	SLC12A3	O95747	OXSR1	S73	E68Q	68	Missense	distal	-5	no	43.984	39.836	EPSD;PhosphoSitePlus	TCGA	17.710	Down-regulation
STE_STE20_FRAY_OXSR1_ST	P55017	SLC12A3	O95747	OXSR1	S73	R80Q	80	Missense	distal	7	no	43.984	44.045	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	17.710	Up-regulation
STE_STE20_FRAY_OXSR1_ST	P55017	SLC12A3	O95747	OXSR1	S73	R80W	80	Missense	distal	7	no	43.984	44.115	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	17.710	Up-regulation
STE_STE20_FRAY_OXSR1_ST	P55017	SLC12A3	O95747	OXSR1	S73	E68K	68	Missense	distal	-5	no	43.984	40.878	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	17.710	Down-regulation
STE_STE20_FRAY_OXSR1_ST	P55017	SLC12A3	O95747	OXSR1	T74	E68Q	68	Missense	distal	-6	no	25.815	26.292	EPSD	TCGA	17.710	Up-regulation
STE_STE20_FRAY_OXSR1_ST	P55017	SLC12A3	O95747	OXSR1	T74	R80Q	80	Missense	distal	6	no	25.815	26.254	EPSD	TCGA;ICGC;COSMIC	17.710	Up-regulation
STE_STE20_FRAY_OXSR1_ST	P55017	SLC12A3	O95747	OXSR1	T74	R80W	80	Missense	distal	6	no	25.815	26.261	EPSD	TCGA;ICGC;COSMIC	17.710	Up-regulation
STE_STE20_FRAY_OXSR1_ST	P55017	SLC12A3	O95747	OXSR1	T74	E68K	68	Missense	distal	-6	no	25.815	26.095	EPSD	TCGA;ICGC;COSMIC	17.710	Up-regulation
TK_Src_SrcA_SRC_Y	Q14790	CASP8	P12931	SRC	Y334	L336F	336	Missense	proximal	2	no	21.016	20.659	EPSD	TCGA;COSMIC	20.673	Loss
TK_Src_SrcA_SRC_Y	Q14790	CASP8	P12931	SRC	Y380	S375F	375	Missense	distal	-5	no	21.749	21.425	EPSD;PhosphoSitePlus	TCGA;COSMIC	20.673	Down-regulation
TK_Src_SrcA_SRC_Y	P60484	PTEN	P12931	SRC	Y27	I28S	28	Missense	proximal	1	no	19.914	21.357	EPSD	TCGA;ICGC;COSMIC	20.673	Gain
TK_Src_SrcA_SRC_Y	P60484	PTEN	P12931	SRC	Y27	I28T	28	Missense	proximal	1	no	19.914	20.703	EPSD	TCGA;ICGC;COSMIC	20.673	Gain
TK_Src_SrcA_SRC_Y	P60484	PTEN	P12931	SRC	Y46	N48I	48	Missense	proximal	2	no	22.622	21.533	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	20.673	Down-regulation
TK_Src_SrcA_SRC_Y	P60484	PTEN	P12931	SRC	Y46	E43K	43	Missense	distal	-3	no	22.622	20.911	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	20.673	Down-regulation
TK_Src_SrcA_SRC_Y	P60484	PTEN	P12931	SRC	Y46	Y46H	46	Missense	central	0	yes	22.622	0.000	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC;CCLE	20.673	Loss
TK_Src_SrcA_SRC_Y	P60484	PTEN	P12931	SRC	Y46	G44D	44	Missense	proximal	-2	no	22.622	22.912	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	20.673	Up-regulation
TK_Src_SrcA_SRC_Y	P60484	PTEN	P12931	SRC	Y46	L42V	42	Missense	distal	-4	no	22.622	22.781	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	20.673	Up-regulation
TK_Src_SrcA_SRC_Y	P60484	PTEN	P12931	SRC	Y46	N48K	48	Missense	proximal	2	no	22.622	21.527	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	20.673	Down-regulation
TK_Src_SrcA_SRC_Y	P60484	PTEN	P12931	SRC	Y46	R47K	47	Missense	proximal	1	no	22.622	22.205	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	20.673	Down-regulation
TK_Src_SrcA_SRC_Y	P60484	PTEN	P12931	SRC	Y46	R47M	47	Missense	proximal	1	no	22.622	22.094	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	20.673	Down-regulation
TK_Src_SrcA_SRC_Y	P60484	PTEN	P12931	SRC	Y46	A39P	39	Missense	distal	-7	no	22.622	22.825	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	20.673	Up-regulation
TK_Src_SrcA_SRC_Y	P60484	PTEN	P12931	SRC	Y46	N49T	49	Missense	distal	3	no	22.622	21.770	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	20.673	Down-regulation
TK_Src_SrcA_SRC_Y	P60484	PTEN	P12931	SRC	Y46	A39V	39	Missense	distal	-7	no	22.622	22.674	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	20.673	Up-regulation
TK_Src_SrcA_SRC_Y	P60484	PTEN	P12931	SRC	Y176	R173C	173	Missense	distal	-3	no	21.281	19.632	EPSD	TCGA;ICGC;COSMIC;GDSC;CCLE	20.673	Loss
TK_Src_SrcA_SRC_Y	P60484	PTEN	P12931	SRC	Y176	R173H	173	Missense	distal	-3	no	21.281	21.245	EPSD	TCGA;ICGC;COSMIC;GDSC;CCLE	20.673	Down-regulation
TK_Src_SrcA_SRC_Y	P60484	PTEN	P12931	SRC	Y176	S170N	170	Missense	distal	-6	no	21.281	21.254	EPSD	TCGA;ICGC;COSMIC	20.673	Down-regulation
TK_Src_SrcA_SRC_Y	P60484	PTEN	P12931	SRC	Y176	Y178C	178	Missense	proximal	2	no	21.281	20.290	EPSD	TCGA;ICGC;COSMIC	20.673	Loss
TK_Src_SrcA_SRC_Y	P60484	PTEN	P12931	SRC	Y176	S170G	170	Missense	distal	-6	no	21.281	21.138	EPSD	TCGA;ICGC;COSMIC	20.673	Down-regulation
TK_Src_SrcA_SRC_Y	P60484	PTEN	P12931	SRC	Y176	Q171K	171	Missense	distal	-5	no	21.281	21.132	EPSD	TCGA;ICGC;COSMIC	20.673	Down-regulation
TK_Src_SrcA_SRC_Y	P60484	PTEN	P12931	SRC	Y176	S170R	170	Missense	distal	-6	no	21.281	21.140	EPSD	TCGA;ICGC;COSMIC	20.673	Down-regulation
TK_Src_SrcA_SRC_Y	P60484	PTEN	P12931	SRC	Y176	S170I	170	Missense	distal	-6	no	21.281	21.258	EPSD	TCGA;ICGC;COSMIC	20.673	Down-regulation
TK_Src_SrcA_SRC_Y	P60484	PTEN	P12931	SRC	Y176	Y177F	177	Missense	proximal	1	no	21.281	19.309	EPSD	TCGA;ICGC;COSMIC	20.673	Loss
TK_Src_SrcA_SRC_Y	P60484	PTEN	P12931	SRC	Y176	Q171R	171	Missense	distal	-5	no	21.281	21.440	EPSD	TCGA;ICGC;COSMIC	20.673	Up-regulation
TK_Src_SrcA_SRC_Y	P60484	PTEN	P12931	SRC	Y176	R173L	173	Missense	distal	-3	no	21.281	20.086	EPSD	TCGA;ICGC;COSMIC	20.673	Loss
TK_Src_SrcA_SRC_Y	P60484	PTEN	P12931	SRC	Y176	L181P	181	Missense	distal	5	no	21.281	21.266	EPSD	TCGA;ICGC;COSMIC	20.673	Down-regulation
TK_Src_SrcA_SRC_Y	P60484	PTEN	P12931	SRC	Y176	Q171E	171	Missense	distal	-5	no	21.281	21.708	EPSD	TCGA;ICGC;COSMIC	20.673	Up-regulation
TK_Src_SrcA_SRC_Y	P60484	PTEN	P12931	SRC	Y176	Y177D	177	Missense	proximal	1	no	21.281	21.679	EPSD	TCGA;ICGC;COSMIC	20.673	Up-regulation
TK_Src_SrcA_SRC_Y	P60484	PTEN	P12931	SRC	Y177	R173C	173	Missense	distal	-4	no	21.132	19.533	EPSD	TCGA;ICGC;COSMIC;GDSC;CCLE	20.673	Loss
TK_Src_SrcA_SRC_Y	P60484	PTEN	P12931	SRC	Y177	R173H	173	Missense	distal	-4	no	21.132	20.648	EPSD	TCGA;ICGC;COSMIC;GDSC;CCLE	20.673	Loss
TK_Src_SrcA_SRC_Y	P60484	PTEN	P12931	SRC	Y177	S170N	170	Missense	distal	-7	no	21.132	21.100	EPSD	TCGA;ICGC;COSMIC	20.673	Down-regulation
TK_Src_SrcA_SRC_Y	P60484	PTEN	P12931	SRC	Y177	Y178C	178	Missense	proximal	1	no	21.132	18.856	EPSD	TCGA;ICGC;COSMIC	20.673	Loss
TK_Src_SrcA_SRC_Y	P60484	PTEN	P12931	SRC	Y177	S170G	170	Missense	distal	-7	no	21.132	20.758	EPSD	TCGA;ICGC;COSMIC	20.673	Down-regulation
TK_Src_SrcA_SRC_Y	P60484	PTEN	P12931	SRC	Y177	Q171K	171	Missense	distal	-6	no	21.132	21.244	EPSD	TCGA;ICGC;COSMIC	20.673	Up-regulation
TK_Src_SrcA_SRC_Y	P60484	PTEN	P12931	SRC	Y177	S170R	170	Missense	distal	-7	no	21.132	21.380	EPSD	TCGA;ICGC;COSMIC	20.673	Up-regulation
TK_Src_SrcA_SRC_Y	P60484	PTEN	P12931	SRC	Y177	S170I	170	Missense	distal	-7	no	21.132	20.876	EPSD	TCGA;ICGC;COSMIC	20.673	Down-regulation
TK_Src_SrcA_SRC_Y	P60484	PTEN	P12931	SRC	Y177	Y177F	177	Missense	central	0	yes	21.132	0.000	EPSD	TCGA;ICGC;COSMIC	20.673	Loss
TK_Src_SrcA_SRC_Y	P60484	PTEN	P12931	SRC	Y177	Q171R	171	Missense	distal	-6	no	21.132	21.030	EPSD	TCGA;ICGC;COSMIC	20.673	Down-regulation
TK_Src_SrcA_SRC_Y	P60484	PTEN	P12931	SRC	Y177	R173L	173	Missense	distal	-4	no	21.132	20.175	EPSD	TCGA;ICGC;COSMIC	20.673	Loss
TK_Src_SrcA_SRC_Y	P60484	PTEN	P12931	SRC	Y177	L181P	181	Missense	distal	4	no	21.132	21.104	EPSD	TCGA;ICGC;COSMIC	20.673	Down-regulation
TK_Src_SrcA_SRC_Y	P60484	PTEN	P12931	SRC	Y177	Q171E	171	Missense	distal	-6	no	21.132	21.256	EPSD	TCGA;ICGC;COSMIC	20.673	Up-regulation
TK_Src_SrcA_SRC_Y	P60484	PTEN	P12931	SRC	Y177	Y177D	177	Missense	central	0	yes	21.132	0.000	EPSD	TCGA;ICGC;COSMIC	20.673	Loss
TK_Src_SrcA_SRC_Y	P60484	PTEN	P12931	SRC	Y178	R173H	173	Missense	distal	-5	no	20.648	20.858	EPSD	TCGA;ICGC;COSMIC;GDSC;CCLE	20.673	Gain
TK_Src_SrcA_SRC_Y	P60484	PTEN	P12931	SRC	Y178	Q171R	171	Missense	distal	-7	no	20.648	20.873	EPSD	TCGA;ICGC;COSMIC	20.673	Gain
TK_Src_SrcA_SRC_Y	P60484	PTEN	P12931	SRC	Y178	L181P	181	Missense	distal	3	no	20.648	20.746	EPSD	TCGA;ICGC;COSMIC	20.673	Gain
TK_Src_SrcA_SRC_Y	P60484	PTEN	P12931	SRC	Y178	Q171E	171	Missense	distal	-7	no	20.648	20.702	EPSD	TCGA;ICGC;COSMIC	20.673	Gain
TK_Src_SrcA_SRC_Y	P60484	PTEN	P12931	SRC	Y240	R233Q	233	Missense	distal	-7	no	21.485	21.261	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC;GDSC;CCLE	20.673	Down-regulation
TK_Src_SrcA_SRC_Y	P60484	PTEN	P12931	SRC	Y240	P246L	246	Missense	distal	6	no	21.485	21.501	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC;CCLE	20.673	Up-regulation
TK_Src_SrcA_SRC_Y	P60484	PTEN	P12931	SRC	Y240	M239R	239	Missense	proximal	-1	no	21.485	20.329	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	20.673	Loss
TK_Src_SrcA_SRC_Y	P60484	PTEN	P12931	SRC	Y240	M239V	239	Missense	proximal	-1	no	21.485	23.091	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	20.673	Up-regulation
TK_Src_SrcA_SRC_Y	P60484	PTEN	P12931	SRC	Y240	P246R	246	Missense	distal	6	no	21.485	21.464	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	20.673	Down-regulation
TK_Src_SrcA_SRC_Y	P60484	PTEN	P12931	SRC	Y240	L247F	247	Missense	distal	7	no	21.485	21.499	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	20.673	Up-regulation
TK_Src_SrcA_SRC_Y	P60484	PTEN	P12931	SRC	Y240	P246S	246	Missense	distal	6	no	21.485	21.469	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	20.673	Down-regulation
TK_Src_SrcA_SRC_Y	P60484	PTEN	P12931	SRC	Y240	Q245P	245	Missense	distal	5	no	21.485	21.613	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	20.673	Up-regulation
TK_Src_SrcA_SRC_Y	P60484	PTEN	P12931	SRC	Y240	F241S	241	Missense	proximal	1	no	21.485	23.362	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC;CCLE	20.673	Up-regulation
TK_Src_SrcA_SRC_Y	P60484	PTEN	P12931	SRC	Y315	D312N	312	Missense	distal	-3	no	24.283	23.775	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	20.673	Down-regulation
TK_Src_SrcA_SRC_Y	P60484	PTEN	P12931	SRC	Y315	K322E	322	Missense	distal	7	no	24.283	24.279	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	20.673	Down-regulation
TK_Src_SrcA_SRC_Y	P60484	PTEN	P12931	SRC	Y315	D310G	310	Missense	distal	-5	no	24.283	24.131	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC;GDSC;CCLE	20.673	Down-regulation
TK_Src_SrcA_SRC_Y	P60484	PTEN	P12931	SRC	Y315	R308C	308	Missense	distal	-7	no	24.283	23.142	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	20.673	Down-regulation
TK_Src_SrcA_SRC_Y	P60484	PTEN	P12931	SRC	Y315	L320S	320	Missense	distal	5	no	24.283	24.092	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	20.673	Down-regulation
TK_Src_SrcA_SRC_Y	P60484	PTEN	P12931	SRC	Y377	E373K	373	Missense	distal	-4	no	20.933	19.763	EPSD;PhosphoSitePlus	TCGA;ICGC	20.673	Loss
TK_Src_SrcA_SRC_Y	P60484	PTEN	P12931	SRC	Y377	N372D	372	Missense	distal	-5	no	20.933	21.145	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	20.673	Up-regulation
TK_Src_SrcA_SRC_Y	P17302	GJA1	P12931	SRC	Y265	Q263K	263	Missense	proximal	-2	no	20.925	20.755	PhosphoSitePlus;EPSD	TCGA;ICGC;COSMIC	20.673	Down-regulation
TK_Src_SrcA_SRC_Y	P17302	GJA1	P12931	SRC	Y265	F268S	268	Missense	distal	3	no	20.925	20.044	PhosphoSitePlus;EPSD	TCGA;ICGC;COSMIC	20.673	Loss
TK_Src_SrcA_SRC_Y	P17302	GJA1	P12931	SRC	Y265	G261V	261	Missense	distal	-4	no	20.925	20.109	PhosphoSitePlus;EPSD	TCGA;ICGC;COSMIC	20.673	Loss
TK_Src_SrcA_SRC_Y	Q13813	SPTAN1	P12931	SRC	Y644	H643N	643	Missense	proximal	-1	no	20.825	19.308	EPSD	TCGA;ICGC;COSMIC	20.673	Loss
TK_Src_SrcA_SRC_Y	Q13813	SPTAN1	P12931	SRC	Y644	H643Y	643	Missense	proximal	-1	no	20.825	21.420	EPSD	TCGA;ICGC;COSMIC	20.673	Up-regulation
TK_Src_SrcA_SRC_Y	Q13813	SPTAN1	P12931	SRC	Y766	R765H	765	Missense	proximal	-1	no	19.188	21.083	EPSD	TCGA;ICGC;COSMIC	20.673	Gain
TK_Src_SrcA_SRC_Y	Q13813	SPTAN1	P12931	SRC	Y976	L975I	975	Missense	proximal	-1	no	20.548	21.283	EPSD	TCGA;ICGC	20.673	Gain
TK_Src_SrcA_SRC_Y	Q13813	SPTAN1	P12931	SRC	Y1073	G1080C	1080	Missense	distal	7	no	23.247	23.326	PhosphoSitePlus;EPSD	TCGA;ICGC;COSMIC	20.673	Up-regulation
TK_Src_SrcA_SRC_Y	Q13813	SPTAN1	P12931	SRC	Y1176	E1183K	1183	Missense	distal	7	no	22.468	22.473	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC;GDSC;CCLE	20.673	Up-regulation
TK_Src_SrcA_SRC_Y	Q13813	SPTAN1	P12931	SRC	Y1176	R1181M	1181	Missense	distal	5	no	22.468	22.835	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	20.673	Up-regulation
TK_Src_SrcA_SRC_Y	Q13813	SPTAN1	P12931	SRC	Y1176	E1183V	1183	Missense	distal	7	no	22.468	22.526	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	20.673	Up-regulation
TK_Src_SrcA_SRC_Y	Q13813	SPTAN1	P12931	SRC	Y1176	A1169S	1169	Missense	distal	-7	no	22.468	22.792	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	20.673	Up-regulation
TK_Src_SrcA_SRC_Y	Q13813	SPTAN1	P12931	SRC	Y1411	E1415K	1415	Missense	distal	4	no	22.713	22.714	EPSD	TCGA;ICGC;COSMIC	20.673	Up-regulation
TK_Src_SrcA_SRC_Y	Q13813	SPTAN1	P12931	SRC	Y1411	G1409R	1409	Missense	proximal	-2	no	22.713	21.355	EPSD	TCGA;ICGC;COSMIC	20.673	Down-regulation
TK_Src_SrcA_SRC_Y	Q13813	SPTAN1	P12931	SRC	Y1579	A1574V	1574	Missense	distal	-5	no	22.200	22.201	EPSD	TCGA;ICGC;COSMIC;CCLE	20.673	Up-regulation
TK_Src_SrcA_SRC_Y	P16035	TIMP2	P12931	SRC	Y62	I66M	66	Missense	distal	4	no	23.336	23.289	EPSD;PhosphoSitePlus	TCGA;COSMIC	20.673	Down-regulation
TK_Src_SrcA_SRC_Y	P35916	FLT4	P12931	SRC	Y833	E829K	829	Missense	distal	-4	no	21.340	20.170	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC;CCLE	20.673	Loss
TK_Src_SrcA_SRC_Y	P35916	FLT4	P12931	SRC	Y853	G854S	854	Missense	proximal	1	no	20.985	20.870	EPSD;PhosphoSitePlus	TCGA	20.673	Down-regulation
TK_Src_SrcA_SRC_Y	P35916	FLT4	P12931	SRC	Y853	L851H	851	Missense	proximal	-2	no	20.985	21.850	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	20.673	Up-regulation
TK_Src_SrcA_SRC_Y	P35916	FLT4	P12931	SRC	Y853	G857R	857	Missense	distal	4	no	20.985	20.983	EPSD;PhosphoSitePlus	TCGA;ICGC	20.673	Down-regulation
TK_Src_SrcA_SRC_Y	P35916	FLT4	P12931	SRC	Y1063	R1060W	1060	Missense	distal	-3	no	20.766	19.556	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	20.673	Loss
TK_Src_SrcA_SRC_Y	P35916	FLT4	P12931	SRC	Y1063	R1070L	1070	Missense	distal	7	no	20.766	20.741	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	20.673	Down-regulation
TK_Src_SrcA_SRC_Y	P35916	FLT4	P12931	SRC	Y1063	R1070S	1070	Missense	distal	7	no	20.766	20.728	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	20.673	Down-regulation
TK_Src_SrcA_SRC_Y	P35916	FLT4	P12931	SRC	Y1063	V1069I	1069	Missense	distal	6	no	20.766	20.773	EPSD;PhosphoSitePlus	TCGA	20.673	Up-regulation
TK_Src_SrcA_SRC_Y	P35916	FLT4	P12931	SRC	Y1063	R1070C	1070	Missense	distal	7	no	20.766	20.838	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	20.673	Up-regulation
TK_Src_SrcA_SRC_Y	P35916	FLT4	P12931	SRC	Y1063	F1056C	1056	Missense	distal	-7	no	20.766	20.205	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	20.673	Loss
TK_Src_SrcA_SRC_Y	P35916	FLT4	P12931	SRC	Y1063	D1061N	1061	Missense	proximal	-2	no	20.766	20.486	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	20.673	Loss
TK_Src_SrcA_SRC_Y	P35916	FLT4	P12931	SRC	Y1063	R1060Q	1060	Missense	distal	-3	no	20.766	21.382	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	20.673	Up-regulation
TK_Src_SrcA_SRC_Y	P35916	FLT4	P12931	SRC	Y1068	R1070L	1070	Missense	proximal	2	no	21.795	21.562	EPSD	TCGA;ICGC;COSMIC	20.673	Down-regulation
TK_Src_SrcA_SRC_Y	P35916	FLT4	P12931	SRC	Y1068	R1070S	1070	Missense	proximal	2	no	21.795	22.626	EPSD	TCGA;ICGC;COSMIC	20.673	Up-regulation
TK_Src_SrcA_SRC_Y	P35916	FLT4	P12931	SRC	Y1068	V1069I	1069	Missense	proximal	1	no	21.795	21.135	EPSD	TCGA	20.673	Down-regulation
TK_Src_SrcA_SRC_Y	P35916	FLT4	P12931	SRC	Y1068	R1070C	1070	Missense	proximal	2	no	21.795	21.195	EPSD	TCGA;ICGC;COSMIC	20.673	Down-regulation
TK_Src_SrcA_SRC_Y	P35916	FLT4	P12931	SRC	Y1068	S1073R	1073	Missense	distal	5	no	21.795	21.819	EPSD	TCGA;ICGC;COSMIC	20.673	Up-regulation
TK_Src_SrcA_SRC_Y	P35916	FLT4	P12931	SRC	Y1068	G1072S	1072	Missense	distal	4	no	21.795	21.820	EPSD	TCGA;ICGC;COSMIC	20.673	Up-regulation
TK_Src_SrcA_SRC_Y	P35916	FLT4	P12931	SRC	Y1068	D1061N	1061	Missense	distal	-7	no	21.795	21.714	EPSD	TCGA;ICGC;COSMIC	20.673	Down-regulation
TK_Src_SrcA_SRC_Y	P35916	FLT4	P12931	SRC	Y1231	A1228T	1228	Missense	distal	-3	no	20.502	20.697	EPSD	TCGA;COSMIC	20.673	Gain
TK_Src_SrcA_SRC_Y	P35916	FLT4	P12931	SRC	Y1337	Q1330R	1330	Missense	distal	-7	no	21.735	21.959	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	20.673	Up-regulation
TK_Src_SrcA_SRC_Y	P35916	FLT4	P12931	SRC	Y1337	S1335N	1335	Missense	proximal	-2	no	21.735	22.357	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	20.673	Up-regulation
TK_Src_SrcA_SRC_Y	P35916	FLT4	P12931	SRC	Y1337	E1339K	1339	Missense	proximal	2	no	21.735	20.565	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	20.673	Loss
TK_Src_SrcA_SRC_Y	P35916	FLT4	P12931	SRC	Y1337	Q1330H	1330	Missense	distal	-7	no	21.735	21.664	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	20.673	Down-regulation
TK_Src_SrcA_SRC_Y	P01112	HRAS	P12931	SRC	Y32	D33N	33	Missense	proximal	1	no	20.815	19.423	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	20.673	Loss
TK_Src_SrcA_SRC_Y	P01112	HRAS	P12931	SRC	Y32	E31K	31	Missense	proximal	-1	no	20.815	18.907	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	20.673	Loss
TK_Src_SrcA_SRC_Y	P01112	HRAS	P12931	SRC	Y64	Q61K	61	Missense	distal	-3	no	23.344	22.513	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC;CCLE	20.673	Down-regulation
TK_Src_SrcA_SRC_Y	P01112	HRAS	P12931	SRC	Y64	Q61L	61	Missense	distal	-3	no	23.344	21.533	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC;GDSC;CCLE	20.673	Down-regulation
TK_Src_SrcA_SRC_Y	P01112	HRAS	P12931	SRC	Y64	G60S	60	Missense	distal	-4	no	23.344	23.056	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	20.673	Down-regulation
TK_Src_SrcA_SRC_Y	P01112	HRAS	P12931	SRC	Y64	Q61H	61	Missense	distal	-3	no	23.344	22.693	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC;GDSC;CCLE	20.673	Down-regulation
TK_Src_SrcA_SRC_Y	P01112	HRAS	P12931	SRC	Y64	Q61R	61	Missense	distal	-3	no	23.344	22.728	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC;GDSC;CCLE	20.673	Down-regulation
TK_Src_SrcA_SRC_Y	P01112	HRAS	P12931	SRC	Y64	Y71H	71	Missense	distal	7	no	23.344	23.382	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	20.673	Up-regulation
TK_Src_SrcA_SRC_Y	P01112	HRAS	P12931	SRC	Y64	G60V	60	Missense	distal	-4	no	23.344	22.528	EPSD;PhosphoSitePlus	TCGA	20.673	Down-regulation
TK_Src_SrcA_SRC_Y	P01112	HRAS	P12931	SRC	Y64	A59T	59	Missense	distal	-5	no	23.344	23.134	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	20.673	Down-regulation
TK_Src_SrcA_SRC_Y	Q9Y2W1	THRAP3	P12931	SRC	Y54	R48S	48	Missense	distal	-6	no	20.852	20.992	EPSD	TCGA;ICGC;COSMIC	20.673	Up-regulation
TK_Src_SrcA_SRC_Y	Q9Y2W1	THRAP3	P12931	SRC	Y54	R50C	50	Missense	distal	-4	no	20.852	19.252	EPSD	TCGA;ICGC;COSMIC	20.673	Loss
TK_Src_SrcA_SRC_Y	Q9Y2W1	THRAP3	P12931	SRC	Y293	Q294E	294	Missense	proximal	1	no	20.674	21.659	EPSD	TCGA;ICGC;COSMIC	20.673	Up-regulation
TK_Src_SrcA_SRC_Y	Q9Y2W1	THRAP3	P12931	SRC	Y293	L287V	287	Missense	distal	-6	no	20.674	20.493	EPSD	TCGA;ICGC;COSMIC	20.673	Loss
TK_Src_SrcA_SRC_Y	Q9Y2W1	THRAP3	P12931	SRC	Y526	K527E	527	Missense	proximal	1	no	20.116	22.510	EPSD	TCGA;ICGC;COSMIC	20.673	Gain
TK_Src_SrcA_SRC_Y	Q9Y2W1	THRAP3	P12931	SRC	Y790	S786L	786	Missense	distal	-4	no	21.316	20.628	EPSD	TCGA;ICGC;COSMIC	20.673	Loss
TK_Src_SrcA_SRC_Y	Q9Y2W1	THRAP3	P12931	SRC	Y790	E797D	797	Missense	distal	7	no	21.316	21.278	EPSD	TCGA;ICGC;COSMIC	20.673	Down-regulation
TK_Src_SrcA_SRC_Y	Q9Y2W1	THRAP3	P12931	SRC	Y795	E797D	797	Missense	proximal	2	no	20.766	20.478	EPSD	TCGA;ICGC;COSMIC	20.673	Loss
TK_Src_SrcA_SRC_Y	P06396	GSN	P12931	SRC	Y465	G470R	470	Missense	distal	5	no	24.763	24.582	PhosphoSitePlus;EPSD	TCGA;COSMIC	20.673	Down-regulation
TK_Src_SrcA_SRC_Y	P06396	GSN	P12931	SRC	Y465	D472Y	472	Missense	distal	7	no	24.763	24.780	PhosphoSitePlus;EPSD	TCGA;COSMIC	20.673	Up-regulation
TK_Src_SrcA_SRC_Y	P06396	GSN	P12931	SRC	Y651	R656Q	656	Missense	distal	5	no	21.179	21.204	EPSD;PhosphoSitePlus	TCGA;COSMIC;GDSC;CCLE	20.673	Up-regulation
TK_Src_SrcA_SRC_Y	Q9H5V8	CDCP1	P12931	SRC	Y283	R276K	276	Missense	distal	-7	no	20.689	20.356	EPSD	TCGA;ICGC;COSMIC	20.673	Loss
TK_Src_SrcA_SRC_Y	Q9H5V8	CDCP1	P12931	SRC	Y734	E738K	738	Missense	distal	4	no	24.372	24.373	PhosphoSitePlus;EPSD	TCGA;ICGC;COSMIC	20.673	Up-regulation
TK_Src_SrcA_SRC_Y	Q9H5V8	CDCP1	P12931	SRC	Y734	D728N	728	Missense	distal	-6	no	24.372	24.182	PhosphoSitePlus;EPSD	TCGA;ICGC;COSMIC	20.673	Down-regulation
TK_Src_SrcA_SRC_Y	Q9H5V8	CDCP1	P12931	SRC	Y743	E738K	738	Missense	distal	-5	no	21.825	21.249	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	20.673	Down-regulation
TK_Src_SrcA_SRC_Y	Q9H5V8	CDCP1	P12931	SRC	Y743	G744R	744	Missense	proximal	1	no	21.825	20.832	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	20.673	Down-regulation
TK_Src_SrcA_SRC_Y	Q9H5V8	CDCP1	P12931	SRC	Y806	H810R	810	Missense	distal	4	no	22.731	22.717	EPSD	TCGA;ICGC;COSMIC	20.673	Down-regulation
TK_Src_SrcA_SRC_Y	P41235	HNF4A	P12931	SRC	Y23	L19P	19	Missense	distal	-4	no	22.972	23.607	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	20.673	Up-regulation
TK_Src_SrcA_SRC_Y	P41235	HNF4A	P12931	SRC	Y286	K290T	290	Missense	distal	4	no	23.521	23.527	EPSD;PhosphoSitePlus	TCGA;COSMIC	20.673	Up-regulation
TK_Src_SrcA_SRC_Y	P41235	HNF4A	P12931	SRC	Y286	Y286F	286	Missense	central	0	yes	23.521	0.000	EPSD;PhosphoSitePlus	TCGA;COSMIC	20.673	Loss
TK_Src_SrcA_SRC_Y	P41235	HNF4A	P12931	SRC	Y286	D282N	282	Missense	distal	-4	no	23.521	22.989	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	20.673	Down-regulation
TK_Src_SrcA_SRC_Y	P41235	HNF4A	P12931	SRC	Y446	E444K	444	Missense	proximal	-2	no	20.896	19.536	EPSD	TCGA;COSMIC	20.673	Loss
TK_Src_SrcA_SRC_Y	P41235	HNF4A	P12931	SRC	Y446	S443Y	443	Missense	distal	-3	no	20.896	19.975	EPSD	TCGA;COSMIC	20.673	Loss
TK_Src_SrcA_SRC_Y	P41235	HNF4A	P12931	SRC	Y446	G442E	442	Missense	distal	-4	no	20.896	21.329	EPSD	TCGA;COSMIC	20.673	Up-regulation
TK_Src_SrcA_SRC_Y	P41235	HNF4A	P12931	SRC	Y446	V453I	453	Missense	distal	7	no	20.896	20.870	EPSD	TCGA;COSMIC	20.673	Down-regulation
TK_Src_SrcA_SRC_Y	P29353	SHC1	P12931	SRC	Y349	P354A	354	Missense	distal	5	no	24.617	24.395	EPSD;PhosphoSitePlus	TCGA;COSMIC	20.673	Down-regulation
TK_Src_SrcA_SRC_Y	P29353	SHC1	P12931	SRC	Y349	F353L	353	Missense	distal	4	no	24.617	24.635	EPSD;PhosphoSitePlus	TCGA;COSMIC	20.673	Up-regulation
TK_Src_SrcA_SRC_Y	P29353	SHC1	P12931	SRC	Y349	P344S	344	Missense	distal	-5	no	24.617	24.719	EPSD;PhosphoSitePlus	TCGA;COSMIC	20.673	Up-regulation
TK_Src_SrcA_SRC_Y	P29353	SHC1	P12931	SRC	Y350	P354A	354	Missense	distal	4	no	21.289	21.308	EPSD;PhosphoSitePlus	TCGA;COSMIC	20.673	Up-regulation
TK_Src_SrcA_SRC_Y	P29353	SHC1	P12931	SRC	Y350	E357K	357	Missense	distal	7	no	21.289	21.293	EPSD;PhosphoSitePlus	TCGA;COSMIC	20.673	Up-regulation
TK_Src_SrcA_SRC_Y	P29353	SHC1	P12931	SRC	Y350	F353L	353	Missense	distal	3	no	21.289	21.048	EPSD;PhosphoSitePlus	TCGA;COSMIC	20.673	Down-regulation
TK_Src_SrcA_SRC_Y	P29353	SHC1	P12931	SRC	Y350	P344S	344	Missense	distal	-6	no	21.289	21.338	EPSD;PhosphoSitePlus	TCGA;COSMIC	20.673	Up-regulation
TK_Src_SrcA_SRC_Y	Q12879	GRIN2A	P12931	SRC	Y1118	R1114T	1114	Missense	distal	-4	no	21.911	21.521	EPSD	TCGA;ICGC;COSMIC	20.673	Down-regulation
TK_Src_SrcA_SRC_Y	Q12879	GRIN2A	P12931	SRC	Y1118	D1121H	1121	Missense	distal	3	no	21.911	22.189	EPSD	TCGA;ICGC;COSMIC	20.673	Up-regulation
TK_Src_SrcA_SRC_Y	Q12879	GRIN2A	P12931	SRC	Y1118	K1116T	1116	Missense	proximal	-2	no	21.911	21.843	EPSD	TCGA;ICGC;COSMIC	20.673	Down-regulation
TK_Src_SrcA_SRC_Y	Q12879	GRIN2A	P12931	SRC	Y1118	P1113L	1113	Missense	distal	-5	no	21.911	21.755	EPSD	TCGA;ICGC;COSMIC	20.673	Down-regulation
TK_Src_SrcA_SRC_Y	Q12879	GRIN2A	P12931	SRC	Y1118	E1125K	1125	Missense	distal	7	no	21.911	21.915	EPSD	TCGA;ICGC;COSMIC	20.673	Up-regulation
TK_Src_SrcA_SRC_Y	Q12879	GRIN2A	P12931	SRC	Y1267	A1261V	1261	Missense	distal	-6	no	23.865	23.705	EPSD;PhosphoSitePlus	TCGA	20.673	Down-regulation
TK_Src_SrcA_SRC_Y	Q12879	GRIN2A	P12931	SRC	Y1267	T1262S	1262	Missense	distal	-5	no	23.865	24.174	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	20.673	Up-regulation
TK_Src_SrcA_SRC_Y	Q12879	GRIN2A	P12931	SRC	Y1267	D1270H	1270	Missense	distal	3	no	23.865	24.144	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	20.673	Up-regulation
TK_Src_SrcA_SRC_Y	Q12879	GRIN2A	P12931	SRC	Y1292	R1288H	1288	Missense	distal	-4	no	21.705	21.221	EPSD	TCGA;ICGC;COSMIC	20.673	Down-regulation
TK_Src_SrcA_SRC_Y	Q12879	GRIN2A	P12931	SRC	Y1292	R1288C	1288	Missense	distal	-4	no	21.705	20.105	EPSD	TCGA;ICGC;COSMIC	20.673	Loss
TK_Src_SrcA_SRC_Y	Q12879	GRIN2A	P12931	SRC	Y1292	D1297N	1297	Missense	distal	5	no	21.705	21.863	EPSD	TCGA;ICGC;COSMIC	20.673	Up-regulation
TK_Src_SrcA_SRC_Y	Q12879	GRIN2A	P12931	SRC	Y1292	Y1292F	1292	Missense	central	0	yes	21.705	0.000	EPSD	TCGA;ICGC;COSMIC	20.673	Loss
TK_Src_SrcA_SRC_Y	Q12879	GRIN2A	P12931	SRC	Y1292	D1293Y	1293	Missense	proximal	1	no	21.705	21.306	EPSD	TCGA;ICGC;COSMIC	20.673	Down-regulation
TK_Src_SrcA_SRC_Y	Q12879	GRIN2A	P12931	SRC	Y1292	Q1289H	1289	Missense	distal	-3	no	21.705	21.054	EPSD	TCGA;ICGC;COSMIC	20.673	Down-regulation
TK_Src_SrcA_SRC_Y	Q12879	GRIN2A	P12931	SRC	Y1292	I1286S	1286	Missense	distal	-6	no	21.705	21.727	EPSD	TCGA;ICGC;COSMIC	20.673	Up-regulation
TK_Src_SrcA_SRC_Y	Q12879	GRIN2A	P12931	SRC	Y1325	R1318Q	1318	Missense	distal	-7	no	24.289	24.064	PhosphoSitePlus;EPSD	TCGA;ICGC;COSMIC	20.673	Down-regulation
TK_Src_SrcA_SRC_Y	Q12879	GRIN2A	P12931	SRC	Y1325	S1330N	1330	Missense	distal	5	no	24.289	24.288	PhosphoSitePlus;EPSD	TCGA;ICGC	20.673	Down-regulation
TK_Src_SrcA_SRC_Y	Q12879	GRIN2A	P12931	SRC	Y1325	G1322E	1322	Missense	distal	-3	no	24.289	24.892	PhosphoSitePlus;EPSD	TCGA;ICGC;COSMIC;GDSC;CCLE	20.673	Up-regulation
TK_Src_SrcA_SRC_Y	Q12879	GRIN2A	P12931	SRC	Y1325	G1326D	1326	Missense	proximal	1	no	24.289	24.666	PhosphoSitePlus;EPSD	TCGA;ICGC;COSMIC	20.673	Up-regulation
TK_Src_SrcA_SRC_Y	Q12879	GRIN2A	P12931	SRC	Y1387	S1390L	1390	Missense	distal	3	no	20.630	21.271	EPSD	TCGA;COSMIC	20.673	Gain
TK_Src_SrcA_SRC_Y	Q12879	GRIN2A	P12931	SRC	Y1423	S1425L	1425	Missense	proximal	2	no	23.431	22.368	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	20.673	Down-regulation
TK_Src_SrcA_SRC_Y	Q12879	GRIN2A	P12931	SRC	Y1423	R1417W	1417	Missense	distal	-6	no	23.431	23.164	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC;CCLE	20.673	Down-regulation
TK_Src_SrcA_SRC_Y	Q12879	GRIN2A	P12931	SRC	Y1423	S1425W	1425	Missense	proximal	2	no	23.431	22.957	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	20.673	Down-regulation
TK_Src_SrcA_SRC_Y	Q12879	GRIN2A	P12931	SRC	Y1423	R1417L	1417	Missense	distal	-6	no	23.431	23.503	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	20.673	Up-regulation
TK_Src_SrcA_SRC_Y	P40763	STAT3	P12931	SRC	Y22	L21V	21	Missense	proximal	-1	no	19.643	20.753	EPSD	TCGA	20.673	Gain
TK_Src_SrcA_SRC_Y	P40763	STAT3	P12931	SRC	Y79	H81L	81	Missense	proximal	2	no	21.754	21.674	EPSD	TCGA;ICGC;COSMIC	20.673	Down-regulation
TK_Src_SrcA_SRC_Y	P40763	STAT3	P12931	SRC	Y446	E444K	444	Missense	proximal	-2	no	21.778	20.419	EPSD	TCGA;ICGC;COSMIC	20.673	Loss
TK_Src_SrcA_SRC_Y	P40763	STAT3	P12931	SRC	Y446	T440I	440	Missense	distal	-6	no	21.778	21.808	EPSD	TCGA	20.673	Up-regulation
TK_Src_SrcA_SRC_Y	O15379	HDAC3	P12931	SRC	Y207	G204C	204	Missense	distal	-3	no	24.457	21.916	EPSD	TCGA;ICGC	20.673	Down-regulation
TK_Src_SrcA_SRC_Y	O15379	HDAC3	P12931	SRC	Y207	P201L	201	Missense	distal	-6	no	24.457	24.437	EPSD	TCGA;ICGC;COSMIC	20.673	Down-regulation
TK_Src_SrcA_SRC_Y	O15379	HDAC3	P12931	SRC	Y331	A333V	333	Missense	proximal	2	no	20.606	20.817	PhosphoSitePlus;EPSD	TCGA;ICGC;COSMIC	20.673	Gain
TK_Src_SrcA_SRC_Y	P52732	KIF11	P12931	SRC	Y125	D130H	130	Missense	distal	5	no	21.964	22.253	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	20.673	Up-regulation
TK_Src_SrcA_SRC_Y	P52732	KIF11	P12931	SRC	Y125	P131L	131	Missense	distal	6	no	21.964	21.980	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	20.673	Up-regulation
TK_Src_SrcA_SRC_Y	P52732	KIF11	P12931	SRC	Y211	N206S	206	Missense	distal	-5	no	23.526	23.655	PhosphoSitePlus;EPSD	TCGA;ICGC;COSMIC	20.673	Up-regulation
TK_Src_SrcA_SRC_Y	P52732	KIF11	P12931	SRC	Y211	Q212H	212	Missense	proximal	1	no	23.526	22.460	PhosphoSitePlus;EPSD	TCGA;ICGC;COSMIC	20.673	Down-regulation
TK_Src_SrcA_SRC_Y	P52732	KIF11	P12931	SRC	Y211	L214F	214	Missense	distal	3	no	23.526	23.767	PhosphoSitePlus;EPSD	TCGA	20.673	Up-regulation
TK_Src_SrcA_SRC_Y	P52732	KIF11	P12931	SRC	Y399	Y399C	399	Missense	central	0	yes	22.269	0.000	EPSD	TCGA;ICGC;COSMIC	20.673	Loss
TK_Src_SrcA_SRC_Y	P31645	SLC6A4	P12931	SRC	Y47	S44P	44	Missense	distal	-3	no	21.046	19.928	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	20.673	Loss
TK_Src_SrcA_SRC_Y	Q7Z3C6	ATG9A	P12931	SRC	Y8	R10H	10	Missense	proximal	2	no	21.985	21.832	PhosphoSitePlus;EPSD	TCGA;ICGC	20.673	Down-regulation
TK_Src_SrcA_SRC_Y	Q7Z3C6	ATG9A	P12931	SRC	Y15	P19S	19	Missense	distal	4	no	21.348	21.369	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	20.673	Up-regulation
TK_Src_SrcA_SRC_Y	Q7Z3C6	ATG9A	P12931	SRC	Y15	R10H	10	Missense	distal	-5	no	21.348	21.557	EPSD;PhosphoSitePlus	TCGA;ICGC	20.673	Up-regulation
TK_Src_SrcA_SRC_Y	Q7Z3C6	ATG9A	P12931	SRC	Y209	R211H	211	Missense	proximal	2	no	20.973	20.820	EPSD	TCGA	20.673	Down-regulation
TK_Src_SrcA_SRC_Y	Q7Z3C6	ATG9A	P12931	SRC	Y209	R214H	214	Missense	distal	5	no	20.973	21.078	EPSD	TCGA;COSMIC	20.673	Up-regulation
TK_Src_SrcA_SRC_Y	P78347	GTF2I	P12931	SRC	Y248	Q250E	250	Missense	proximal	2	no	22.681	22.990	PhosphoSitePlus;EPSD	TCGA;ICGC;COSMIC	20.673	Up-regulation
TK_Src_SrcA_SRC_Y	P78347	GTF2I	P12931	SRC	Y248	Y251C	251	Missense	distal	3	no	22.681	21.606	PhosphoSitePlus;EPSD	TCGA;ICGC;COSMIC	20.673	Down-regulation
TK_Src_SrcA_SRC_Y	P78347	GTF2I	P12931	SRC	Y249	Q250E	250	Missense	proximal	1	no	23.134	24.119	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	20.673	Up-regulation
TK_Src_SrcA_SRC_Y	P78347	GTF2I	P12931	SRC	Y249	Y251C	251	Missense	proximal	2	no	23.134	22.143	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	20.673	Down-regulation
TK_Src_SrcA_SRC_Y	P78347	GTF2I	P12931	SRC	Y398	G401R	401	Missense	distal	3	no	21.584	20.299	EPSD	TCGA;COSMIC	20.673	Loss
TK_Src_SrcA_SRC_Y	P16885	PLCG2	P12931	SRC	Y720	V717I	717	Missense	distal	-3	no	21.309	20.203	EPSD	TCGA;ICGC;COSMIC	20.673	Loss
TK_Src_SrcA_SRC_Y	P16885	PLCG2	P12931	SRC	Y720	R727Q	727	Missense	distal	7	no	21.309	21.266	EPSD	TCGA;ICGC;COSMIC;GDSC;CCLE	20.673	Down-regulation
TK_Src_SrcA_SRC_Y	P16885	PLCG2	P12931	SRC	Y753	D754N	754	Missense	proximal	1	no	21.079	19.687	PhosphoSitePlus;EPSD	TCGA;ICGC;COSMIC	20.673	Loss
TK_Src_SrcA_SRC_Y	P16885	PLCG2	P12931	SRC	Y753	D754A	754	Missense	proximal	1	no	21.079	20.387	PhosphoSitePlus;EPSD	TCGA;ICGC;COSMIC	20.673	Loss
TK_Src_SrcA_SRC_Y	P16885	PLCG2	P12931	SRC	Y753	V755I	755	Missense	proximal	2	no	21.079	19.884	PhosphoSitePlus;EPSD	TCGA;ICGC;COSMIC	20.673	Loss
TK_Src_SrcA_SRC_Y	P16885	PLCG2	P12931	SRC	Y1048	M1043V	1043	Missense	distal	-5	no	22.202	22.520	EPSD	TCGA;ICGC;COSMIC	20.673	Up-regulation
TK_Src_SrcA_SRC_Y	P16885	PLCG2	P12931	SRC	Y1048	E1046D	1046	Missense	proximal	-2	no	22.202	21.914	EPSD	TCGA;ICGC;COSMIC	20.673	Down-regulation
TK_Src_SrcA_SRC_Y	P16885	PLCG2	P12931	SRC	Y1137	F1134V	1134	Missense	distal	-3	no	20.388	21.526	EPSD	TCGA;ICGC	20.673	Gain
TK_Src_SrcA_SRC_Y	P16885	PLCG2	P12931	SRC	Y1137	D1140N	1140	Missense	distal	3	no	20.388	21.464	EPSD	TCGA;ICGC;COSMIC	20.673	Gain
TK_Src_SrcA_SRC_Y	P16885	PLCG2	P12931	SRC	Y1197	E1194D	1194	Missense	distal	-3	no	23.077	23.122	EPSD	TCGA;ICGC;COSMIC	20.673	Up-regulation
TK_Src_SrcA_SRC_Y	P16885	PLCG2	P12931	SRC	Y1197	S1198A	1198	Missense	proximal	1	no	23.077	22.877	EPSD	TCGA;ICGC;COSMIC	20.673	Down-regulation
TK_Src_SrcA_SRC_Y	P16885	PLCG2	P12931	SRC	Y1197	R1201H	1201	Missense	distal	4	no	23.077	23.090	EPSD	TCGA;ICGC;COSMIC	20.673	Up-regulation
TK_Src_SrcA_SRC_Y	P19022	CDH2	P12931	SRC	Y496	V491I	491	Missense	distal	-5	no	21.765	21.557	EPSD	TCGA;COSMIC	20.673	Down-regulation
TK_Src_SrcA_SRC_Y	P19022	CDH2	P12931	SRC	Y496	K502N	502	Missense	distal	6	no	21.765	21.721	EPSD	TCGA;COSMIC	20.673	Down-regulation
TK_Src_SrcA_SRC_Y	P19022	CDH2	P12931	SRC	Y496	E493V	493	Missense	distal	-3	no	21.765	19.886	EPSD	TCGA;COSMIC	20.673	Loss
TK_Src_SrcA_SRC_Y	P19022	CDH2	P12931	SRC	Y496	P501R	501	Missense	distal	5	no	21.765	21.612	EPSD	TCGA;COSMIC	20.673	Down-regulation
TK_Src_SrcA_SRC_Y	P19022	CDH2	P12931	SRC	Y496	P501S	501	Missense	distal	5	no	21.765	21.588	EPSD	TCGA;COSMIC	20.673	Down-regulation
TK_Src_SrcA_SRC_Y	P19022	CDH2	P12931	SRC	Y496	V491L	491	Missense	distal	-5	no	21.765	21.604	EPSD	TCGA;COSMIC	20.673	Down-regulation
TK_Src_SrcA_SRC_Y	P19022	CDH2	P12931	SRC	Y496	F497L	497	Missense	proximal	1	no	21.765	22.096	EPSD	TCGA;COSMIC	20.673	Up-regulation
TK_Src_SrcA_SRC_Y	P19022	CDH2	P12931	SRC	Y820	R823L	823	Missense	distal	3	no	20.104	21.793	EPSD;PhosphoSitePlus	TCGA;COSMIC	20.673	Gain
TK_Src_SrcA_SRC_Y	P19022	CDH2	P12931	SRC	Y884	S877R	877	Missense	distal	-7	no	22.289	22.537	PhosphoSitePlus;EPSD	TCGA;COSMIC	20.673	Up-regulation
TK_Src_SrcA_SRC_Y	P19022	CDH2	P12931	SRC	Y884	D889N	889	Missense	distal	5	no	22.289	22.447	PhosphoSitePlus;EPSD	TCGA;COSMIC	20.673	Up-regulation
TK_Src_SrcA_SRC_Y	P19022	CDH2	P12931	SRC	Y884	S878I	878	Missense	distal	-6	no	22.289	22.266	PhosphoSitePlus;EPSD	TCGA;COSMIC	20.673	Down-regulation
TK_Src_SrcA_SRC_Y	P30411	BDKRB2	P12931	SRC	Y347	G349E	349	Missense	proximal	2	no	20.555	21.510	PhosphoSitePlus;EPSD	TCGA;ICGC	20.673	Gain
TK_Src_SrcA_SRC_Y	Q96J92	WNK4	P12931	SRC	Y348	K351N	351	Missense	distal	3	no	19.178	21.496	EPSD	TCGA;ICGC;COSMIC	20.673	Gain
TK_Src_SrcA_SRC_Y	Q96J92	WNK4	P12931	SRC	Y375	E372Q	372	Missense	distal	-3	no	20.778	19.898	EPSD	TCGA;ICGC;COSMIC	20.673	Loss
TK_Src_SrcA_SRC_Y	Q96J92	WNK4	P12931	SRC	Y375	S376F	376	Missense	proximal	1	no	20.778	18.901	EPSD	TCGA;ICGC;COSMIC	20.673	Loss
TK_Src_SrcA_SRC_Y	Q96J92	WNK4	P12931	SRC	Y1164	R1166W	1166	Missense	proximal	2	no	23.734	24.091	PhosphoSitePlus;EPSD	TCGA;ICGC;COSMIC	20.673	Up-regulation
TK_Src_SrcA_SRC_Y	Q96J92	WNK4	P12931	SRC	Y1164	S1165R	1165	Missense	proximal	1	no	23.734	22.855	PhosphoSitePlus;EPSD	TCGA;ICGC;COSMIC	20.673	Down-regulation
TK_Src_SrcA_SRC_Y	Q96J92	WNK4	P12931	SRC	Y1164	R1166Q	1166	Missense	proximal	2	no	23.734	24.083	PhosphoSitePlus;EPSD	TCGA;ICGC;COSMIC	20.673	Up-regulation
TK_Src_SrcA_SRC_Y	Q03135	CAV1	P12931	SRC	Y14	G11A	11	Missense	distal	-3	no	22.478	21.754	PhosphoSitePlus	TCGA;ICGC;COSMIC	20.673	Down-regulation
TK_Src_SrcA_SRC_Y	Q03135	CAV1	P12931	SRC	Y14	E10K	10	Missense	distal	-4	no	22.478	21.308	PhosphoSitePlus	TCGA;ICGC;COSMIC	20.673	Down-regulation
TK_Src_SrcA_SRC_Y	Q03135	CAV1	P12931	SRC	Y14	E20K	20	Missense	distal	6	no	22.478	22.476	PhosphoSitePlus	TCGA;ICGC;COSMIC	20.673	Down-regulation
TK_Src_SrcA_SRC_Y	Q03135	CAV1	P12931	SRC	Y14	V7A	7	Missense	distal	-7	no	22.478	22.427	PhosphoSitePlus	TCGA;ICGC;COSMIC	20.673	Down-regulation
TK_Src_SrcA_SRC_Y	Q03135	CAV1	P12931	SRC	Y14	T15A	15	Missense	proximal	1	no	22.478	22.933	PhosphoSitePlus	TCGA;ICGC;COSMIC	20.673	Up-regulation
TK_Src_SrcA_SRC_Y	Q03135	CAV1	P12931	SRC	Y14	R19Q	19	Missense	distal	5	no	22.478	22.503	PhosphoSitePlus	TCGA;ICGC;COSMIC	20.673	Up-regulation
TK_Src_SrcA_SRC_Y	Q03135	CAV1	P12931	SRC	Y25	E20K	20	Missense	distal	-5	no	21.787	21.211	EPSD	TCGA;ICGC;COSMIC	20.673	Down-regulation
TK_Src_SrcA_SRC_Y	Q03135	CAV1	P12931	SRC	Y25	R19Q	19	Missense	distal	-6	no	21.787	21.890	EPSD	TCGA;ICGC;COSMIC	20.673	Up-regulation
TK_Src_SrcA_SRC_Y	P35790	CHKA	P12931	SRC	Y333	M327I	327	Missense	distal	-6	no	20.473	20.992	EPSD;PhosphoSitePlus	TCGA;COSMIC	20.673	Gain
TK_Src_SrcA_SRC_Y	Q9Y2X7	GIT1	P12931	SRC	Y224	R229Q	229	Missense	distal	5	no	21.866	21.891	EPSD	TCGA	20.673	Up-regulation
TK_Src_SrcA_SRC_Y	Q9Y2X7	GIT1	P12931	SRC	Y284	E286K	286	Missense	proximal	2	no	23.461	22.292	PhosphoSitePlus;EPSD	TCGA;COSMIC	20.673	Down-regulation
TK_Src_SrcA_SRC_Y	Q13480	GAB1	P12931	SRC	Y259	L261R	261	Missense	proximal	2	no	20.690	20.922	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	20.673	Up-regulation
TK_Src_SrcA_SRC_Y	Q13480	GAB1	P12931	SRC	Y285	T289N	289	Missense	distal	4	no	22.654	22.692	EPSD	TCGA;ICGC;COSMIC	20.673	Up-regulation
TK_Src_SrcA_SRC_Y	Q13480	GAB1	P12931	SRC	Y406	R410Q	410	Missense	distal	4	no	21.248	21.270	EPSD	TCGA;ICGC;COSMIC	20.673	Up-regulation
TK_Src_SrcA_SRC_Y	Q13480	GAB1	P12931	SRC	Y447	P452L	452	Missense	distal	5	no	20.885	20.899	EPSD	TCGA;ICGC;COSMIC	20.673	Up-regulation
TK_Src_SrcA_SRC_Y	Q13480	GAB1	P12931	SRC	Y447	M450K	450	Missense	distal	3	no	20.885	19.259	EPSD	TCGA;ICGC;COSMIC	20.673	Loss
TK_Src_SrcA_SRC_Y	O43823	AKAP8	P12931	SRC	Y146	E142K	142	Missense	distal	-4	no	21.034	19.864	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	20.673	Loss
TK_Src_SrcA_SRC_Y	O43823	AKAP8	P12931	SRC	Y146	R147L	147	Missense	proximal	1	no	21.034	20.367	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	20.673	Loss
TK_Src_SrcA_SRC_Y	O43823	AKAP8	P12931	SRC	Y146	P145L	145	Missense	proximal	-1	no	21.034	21.020	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	20.673	Down-regulation
TK_Src_SrcA_SRC_Y	O43823	AKAP8	P12931	SRC	Y146	Y152C	152	Missense	distal	6	no	21.034	21.075	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	20.673	Up-regulation
TK_Src_SrcA_SRC_Y	O43823	AKAP8	P12931	SRC	Y170	S171N	171	Missense	proximal	1	no	21.005	20.106	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	20.673	Loss
TK_Src_SrcA_SRC_Y	O43823	AKAP8	P12931	SRC	Y170	F166S	166	Missense	distal	-4	no	21.005	21.924	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	20.673	Up-regulation
TK_Src_SrcA_SRC_Y	O43823	AKAP8	P12931	SRC	Y311	L310P	310	Missense	proximal	-1	no	20.837	20.851	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	20.673	Up-regulation
TK_Src_SrcA_SRC_Y	O43823	AKAP8	P12931	SRC	Y311	P314A	314	Missense	distal	3	no	20.837	20.143	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	20.673	Loss
TK_Src_SrcA_SRC_Y	Q92945	KHSRP	P12931	SRC	Y149	Y149C	149	Missense	central	0	yes	21.215	0.000	EPSD	TCGA;ICGC	20.673	Loss
TK_Src_SrcA_SRC_Y	Q92945	KHSRP	P12931	SRC	Y317	S319C	319	Missense	proximal	2	no	21.728	20.296	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	20.673	Loss
TK_Src_SrcA_SRC_Y	Q92945	KHSRP	P12931	SRC	Y317	R314Q	314	Missense	distal	-3	no	21.728	22.344	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	20.673	Up-regulation
TK_Src_SrcA_SRC_Y	Q92945	KHSRP	P12931	SRC	Y317	R320W	320	Missense	distal	3	no	21.728	21.631	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	20.673	Down-regulation
TK_Src_SrcA_SRC_Y	Q92945	KHSRP	P12931	SRC	Y674	A676V	676	Missense	proximal	2	no	21.239	21.450	EPSD	TCGA;ICGC;COSMIC	20.673	Up-regulation
TK_Src_SrcA_SRC_Y	P61978	HNRNPK	P12931	SRC	Y225	D231N	231	Missense	distal	6	no	24.096	24.100	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	20.673	Up-regulation
TK_Src_SrcA_SRC_Y	P61978	HNRNPK	P12931	SRC	Y225	R221H	221	Missense	distal	-4	no	24.096	23.612	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	20.673	Down-regulation
TK_Src_SrcA_SRC_Y	P61978	HNRNPK	P12931	SRC	Y230	D231N	231	Missense	proximal	1	no	20.802	19.410	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	20.673	Loss
TK_Src_SrcA_SRC_Y	P61978	HNRNPK	P12931	SRC	Y230	G237D	237	Missense	distal	7	no	20.802	20.740	EPSD;PhosphoSitePlus	TCGA;ICGC	20.673	Down-regulation
TK_Src_SrcA_SRC_Y	P61978	HNRNPK	P12931	SRC	Y230	T233A	233	Missense	distal	3	no	20.802	20.757	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	20.673	Down-regulation
TK_Src_SrcA_SRC_Y	P61978	HNRNPK	P12931	SRC	Y234	M241I	241	Missense	distal	7	no	23.464	23.438	PhosphoSitePlus;EPSD	TCGA;ICGC;COSMIC	20.673	Down-regulation
TK_Src_SrcA_SRC_Y	P61978	HNRNPK	P12931	SRC	Y234	T240A	240	Missense	distal	6	no	23.464	23.478	PhosphoSitePlus;EPSD	TCGA;ICGC;COSMIC	20.673	Up-regulation
TK_Src_SrcA_SRC_Y	P61978	HNRNPK	P12931	SRC	Y234	D231N	231	Missense	distal	-3	no	23.464	22.956	PhosphoSitePlus;EPSD	TCGA;ICGC;COSMIC	20.673	Down-regulation
TK_Src_SrcA_SRC_Y	P61978	HNRNPK	P12931	SRC	Y234	G237D	237	Missense	distal	3	no	23.464	23.091	PhosphoSitePlus;EPSD	TCGA;ICGC	20.673	Down-regulation
TK_Src_SrcA_SRC_Y	P61978	HNRNPK	P12931	SRC	Y234	T233A	233	Missense	proximal	-1	no	23.464	23.481	PhosphoSitePlus;EPSD	TCGA;ICGC;COSMIC	20.673	Up-regulation
TK_Src_SrcA_SRC_Y	P61978	HNRNPK	P12931	SRC	Y236	M241I	241	Missense	distal	5	no	22.448	22.204	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	20.673	Down-regulation
TK_Src_SrcA_SRC_Y	P61978	HNRNPK	P12931	SRC	Y236	T240A	240	Missense	distal	4	no	22.448	22.452	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	20.673	Up-regulation
TK_Src_SrcA_SRC_Y	P61978	HNRNPK	P12931	SRC	Y236	D231N	231	Missense	distal	-5	no	22.448	22.235	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	20.673	Down-regulation
TK_Src_SrcA_SRC_Y	P61978	HNRNPK	P12931	SRC	Y236	G237D	237	Missense	proximal	1	no	22.448	22.826	EPSD;PhosphoSitePlus	TCGA;ICGC	20.673	Up-regulation
TK_Src_SrcA_SRC_Y	P61978	HNRNPK	P12931	SRC	Y236	T233A	233	Missense	distal	-3	no	22.448	22.253	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	20.673	Down-regulation
TK_Src_SrcA_SRC_Y	P61978	HNRNPK	P12931	SRC	Y333	R332H	332	Missense	proximal	-1	no	20.981	22.876	EPSD	TCGA;ICGC;COSMIC	20.673	Up-regulation
TK_Src_SrcA_SRC_Y	P61978	HNRNPK	P12931	SRC	Y333	R328I	328	Missense	distal	-5	no	20.981	20.759	EPSD	TCGA;ICGC	20.673	Down-regulation
TK_Src_SrcA_SRC_Y	P61978	HNRNPK	P12931	SRC	Y369	A374S	374	Missense	distal	5	no	20.658	20.703	EPSD	TCGA;ICGC;COSMIC	20.673	Gain
TK_Src_SrcA_SRC_Y	P26010	ITGB7	P12931	SRC	Y758	R755H	755	Missense	distal	-3	no	23.252	23.217	PhosphoSitePlus;EPSD	TCGA;COSMIC	20.673	Down-regulation
TK_Src_SrcA_SRC_Y	P26010	ITGB7	P12931	SRC	Y758	R760H	760	Missense	proximal	2	no	23.252	23.099	PhosphoSitePlus;EPSD	TCGA;COSMIC	20.673	Down-regulation
TK_Src_SrcA_SRC_Y	P26010	ITGB7	P12931	SRC	Y778	P776L	776	Missense	proximal	-2	no	20.987	19.456	EPSD	TCGA;COSMIC	20.673	Loss
TK_Src_SrcA_SRC_Y	P26010	ITGB7	P12931	SRC	Y778	S780R	780	Missense	proximal	2	no	20.987	20.156	EPSD	TCGA;COSMIC	20.673	Loss
TK_Src_SrcA_SRC_Y	P26010	ITGB7	P12931	SRC	Y778	S780N	780	Missense	proximal	2	no	20.987	20.739	EPSD	TCGA;COSMIC	20.673	Down-regulation
TK_Src_SrcA_SRC_Y	P23246	SFPQ	P12931	SRC	Y293	R287K	287	Missense	distal	-6	no	21.695	21.909	EPSD	TCGA	20.673	Up-regulation
TK_Src_SrcA_SRC_Y	P23246	SFPQ	P12931	SRC	Y293	R296L	296	Missense	distal	3	no	21.695	23.383	EPSD	TCGA;ICGC;COSMIC	20.673	Up-regulation
TK_Src_SrcA_SRC_Y	P23246	SFPQ	P12931	SRC	Y293	E290K	290	Missense	distal	-3	no	21.695	19.984	EPSD	TCGA;ICGC;COSMIC	20.673	Loss
TK_Src_SrcA_SRC_Y	P23246	SFPQ	P12931	SRC	Y488	A481T	481	Missense	distal	-7	no	21.123	21.543	EPSD	TCGA;ICGC	20.673	Up-regulation
TK_Src_SrcA_SRC_Y	P23246	SFPQ	P12931	SRC	Y597	E595G	595	Missense	proximal	-2	no	22.451	21.874	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	20.673	Down-regulation
TK_Src_SrcA_SRC_Y	P23246	SFPQ	P12931	SRC	Y597	Y602F	602	Missense	distal	5	no	22.451	22.287	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	20.673	Down-regulation
TK_Src_SrcA_SRC_Y	P23246	SFPQ	P12931	SRC	Y597	Y597H	597	Missense	central	0	yes	22.451	0.000	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	20.673	Loss
TK_Src_SrcA_SRC_Y	P23246	SFPQ	P12931	SRC	Y597	R591H	591	Missense	distal	-6	no	22.451	22.418	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	20.673	Down-regulation
TK_Src_SrcA_SRC_Y	P23246	SFPQ	P12931	SRC	Y698	E697Q	697	Missense	proximal	-1	no	21.343	20.937	EPSD	TCGA;ICGC	20.673	Down-regulation
TK_Src_SrcA_SRC_Y	P23246	SFPQ	P12931	SRC	Y698	K703Q	703	Missense	distal	5	no	21.343	21.311	EPSD	TCGA;ICGC;COSMIC	20.673	Down-regulation
TK_Src_SrcA_SRC_Y	P23246	SFPQ	P12931	SRC	Y698	R693I	693	Missense	distal	-5	no	21.343	21.121	EPSD	TCGA;ICGC;COSMIC	20.673	Down-regulation
TK_Src_SrcA_SRC_Y	O14641	DVL2	P12931	SRC	Y27	E24Q	24	Missense	distal	-3	no	20.822	19.941	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	20.673	Loss
TK_Src_SrcA_SRC_Y	O14641	DVL2	P12931	SRC	Y27	E24D	24	Missense	distal	-3	no	20.822	20.867	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	20.673	Up-regulation
TK_Src_SrcA_SRC_Y	O14641	DVL2	P12931	SRC	Y295	I294M	294	Missense	proximal	-1	no	21.058	19.827	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	20.673	Loss
TK_Src_SrcA_SRC_Y	O14641	DVL2	P12931	SRC	Y295	M300I	300	Missense	distal	5	no	21.058	20.814	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	20.673	Down-regulation
TK_Src_SrcA_SRC_Y	O14641	DVL2	P12931	SRC	Y295	R289W	289	Missense	distal	-6	no	21.058	20.790	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC;GDSC;CCLE	20.673	Down-regulation
TK_Src_SrcA_SRC_Y	P15311	EZR	P12931	SRC	Y116	G109R	109	Missense	distal	-7	no	20.745	21.367	EPSD	TCGA;ICGC;COSMIC	20.673	Up-regulation
TK_Src_SrcA_SRC_Y	P15311	EZR	P12931	SRC	Y116	L111F	111	Missense	distal	-5	no	20.745	20.681	EPSD	TCGA;ICGC;COSMIC	20.673	Down-regulation
TK_Src_SrcA_SRC_Y	P15311	EZR	P12931	SRC	Y478	P480Q	480	Missense	proximal	2	no	25.069	25.194	PhosphoSitePlus;EPSD	TCGA;ICGC;COSMIC	20.673	Up-regulation
TK_Src_SrcA_SRC_Y	Q15139	PRKD1	P12931	SRC	Y463	E470G	470	Missense	distal	7	no	21.351	21.375	EPSD;PhosphoSitePlus	TCGA;COSMIC	20.673	Up-regulation
TK_Src_SrcA_SRC_Y	Q15139	PRKD1	P12931	SRC	Y502	G504E	504	Missense	proximal	2	no	21.516	22.471	EPSD;PhosphoSitePlus	TCGA;COSMIC	20.673	Up-regulation
TK_Src_SrcA_SRC_Y	Q15139	PRKD1	P12931	SRC	Y749	E753G	753	Missense	distal	4	no	21.703	21.691	EPSD	TCGA;COSMIC	20.673	Down-regulation
TK_Src_SrcA_SRC_Y	Q15139	PRKD1	P12931	SRC	Y749	P747T	747	Missense	proximal	-2	no	21.703	20.679	EPSD	TCGA;COSMIC	20.673	Down-regulation
TK_Src_SrcA_SRC_Y	Q15139	PRKD1	P12931	SRC	Y749	A748S	748	Missense	proximal	-1	no	21.703	21.592	EPSD	TCGA;COSMIC	20.673	Down-regulation
TK_Src_SrcA_SRC_Y	Q15139	PRKD1	P12931	SRC	Y749	T746A	746	Missense	distal	-3	no	21.703	21.508	EPSD	TCGA	20.673	Down-regulation
TK_Src_SrcA_SRC_Y	Q93052	LPP	P12931	SRC	Y244	Y244F	244	Missense	central	0	yes	22.155	0.000	PhosphoSitePlus;EPSD	TCGA;ICGC;COSMIC	20.673	Loss
TK_Src_SrcA_SRC_Y	Q93052	LPP	P12931	SRC	Y244	I243M	243	Missense	proximal	-1	no	22.155	20.923	PhosphoSitePlus;EPSD	TCGA;ICGC	20.673	Down-regulation
TK_Src_SrcA_SRC_Y	Q93052	LPP	P12931	SRC	Y244	G250V	250	Missense	distal	6	no	22.155	22.149	PhosphoSitePlus;EPSD	TCGA;ICGC	20.673	Down-regulation
TK_Src_SrcA_SRC_Y	Q93052	LPP	P12931	SRC	Y287	G286R	286	Missense	proximal	-1	no	21.800	21.029	EPSD	TCGA;ICGC;COSMIC	20.673	Down-regulation
TK_Src_SrcA_SRC_Y	Q93052	LPP	P12931	SRC	Y287	G280E	280	Missense	distal	-7	no	21.800	22.251	EPSD	TCGA;ICGC;COSMIC	20.673	Up-regulation
TK_Src_SrcA_SRC_Y	Q93052	LPP	P12931	SRC	Y301	G308R	308	Missense	distal	7	no	22.380	22.387	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	20.673	Up-regulation
TK_Src_SrcA_SRC_Y	Q93052	LPP	P12931	SRC	Y317	P323S	323	Missense	distal	6	no	23.340	23.324	EPSD	TCGA;ICGC;COSMIC	20.673	Down-regulation
TK_Src_SrcA_SRC_Y	Q93052	LPP	P12931	SRC	Y317	P315L	315	Missense	proximal	-2	no	23.340	21.809	EPSD	TCGA;ICGC;COSMIC	20.673	Down-regulation
TK_Src_SrcA_SRC_Y	Q93052	LPP	P12931	SRC	Y317	R310I	310	Missense	distal	-7	no	23.340	22.836	EPSD	TCGA;ICGC	20.673	Down-regulation
TK_Src_SrcA_SRC_Y	Q93052	LPP	P12931	SRC	Y332	R328W	328	Missense	distal	-4	no	20.717	19.344	EPSD	TCGA;ICGC;COSMIC	20.673	Loss
TK_Src_SrcA_SRC_Y	Q93052	LPP	P12931	SRC	Y332	G336A	336	Missense	distal	4	no	20.717	20.740	EPSD	TCGA;ICGC;COSMIC	20.673	Up-regulation
TK_Src_SrcA_SRC_Y	P53355	DAPK1	P12931	SRC	Y12	R5G	5	Missense	distal	-7	no	21.097	20.475	EPSD	TCGA;ICGC;COSMIC	20.673	Loss
TK_Src_SrcA_SRC_Y	P53355	DAPK1	P12931	SRC	Y12	N8S	8	Missense	distal	-4	no	21.097	20.682	EPSD	TCGA;ICGC;COSMIC	20.673	Down-regulation
TK_Src_SrcA_SRC_Y	P53355	DAPK1	P12931	SRC	Y12	G16R	16	Missense	distal	4	no	21.097	21.095	EPSD	TCGA;ICGC;COSMIC	20.673	Down-regulation
TK_Src_SrcA_SRC_Y	P53355	DAPK1	P12931	SRC	Y13	N8S	8	Missense	distal	-5	no	22.105	22.233	EPSD	TCGA;ICGC;COSMIC	20.673	Up-regulation
TK_Src_SrcA_SRC_Y	P53355	DAPK1	P12931	SRC	Y13	G16R	16	Missense	distal	3	no	22.105	20.820	EPSD	TCGA;ICGC;COSMIC	20.673	Down-regulation
TK_Src_SrcA_SRC_Y	O15492	RGS16	P12931	SRC	Y168	P169S	169	Missense	proximal	1	no	21.869	24.014	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	20.673	Up-regulation
TK_Src_SrcA_SRC_Y	O15492	RGS16	P12931	SRC	Y168	L162Q	162	Missense	distal	-6	no	21.869	21.900	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	20.673	Up-regulation
TK_Src_SrcA_SRC_Y	O15492	RGS16	P12931	SRC	Y168	S174L	174	Missense	distal	6	no	21.869	21.901	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	20.673	Up-regulation
TK_Src_SrcA_SRC_Y	O15492	RGS16	P12931	SRC	Y168	L162P	162	Missense	distal	-6	no	21.869	21.889	EPSD;PhosphoSitePlus	TCGA;ICGC	20.673	Up-regulation
TK_Src_SrcA_SRC_Y	O15492	RGS16	P12931	SRC	Y177	R178W	178	Missense	proximal	1	no	21.421	21.338	PhosphoSitePlus;EPSD	TCGA;ICGC;COSMIC	20.673	Down-regulation
TK_Src_SrcA_SRC_Y	O15492	RGS16	P12931	SRC	Y177	S174L	174	Missense	distal	-3	no	21.421	19.153	PhosphoSitePlus;EPSD	TCGA;ICGC;COSMIC	20.673	Loss
TK_Src_SrcA_SRC_Y	Q9Y371	SH3GLB1	P12931	SRC	Y80	R85T	85	Missense	distal	5	no	23.958	24.103	PhosphoSitePlus	TCGA;ICGC;COSMIC	20.673	Up-regulation
TK_Src_SrcA_SRC_Y	Q9Y371	SH3GLB1	P12931	SRC	Y80	F78C	78	Missense	proximal	-2	no	23.958	23.698	PhosphoSitePlus	TCGA;ICGC;COSMIC	20.673	Down-regulation
TK_Src_SrcA_SRC_Y	Q9UPT8	ZC3H4	P12931	SRC	Y196	Y201C	201	Missense	distal	5	no	23.086	23.131	EPSD	TCGA;ICGC;COSMIC	20.673	Up-regulation
TK_Src_SrcA_SRC_Y	Q9UPT8	ZC3H4	P12931	SRC	Y201	D207E	207	Missense	distal	6	no	22.368	22.418	EPSD	TCGA;ICGC;COSMIC	20.673	Up-regulation
TK_Src_SrcA_SRC_Y	Q9UPT8	ZC3H4	P12931	SRC	Y201	D207N	207	Missense	distal	6	no	22.368	22.372	EPSD	TCGA;ICGC;COSMIC	20.673	Up-regulation
TK_Src_SrcA_SRC_Y	Q9UPT8	ZC3H4	P12931	SRC	Y201	Y201C	201	Missense	central	0	yes	22.368	0.000	EPSD	TCGA;ICGC;COSMIC	20.673	Loss
TK_Src_SrcA_SRC_Y	Q9UPT8	ZC3H4	P12931	SRC	Y204	D207E	207	Missense	distal	3	no	21.334	21.428	EPSD	TCGA;ICGC;COSMIC	20.673	Up-regulation
TK_Src_SrcA_SRC_Y	Q9UPT8	ZC3H4	P12931	SRC	Y204	D207N	207	Missense	distal	3	no	21.334	22.409	EPSD	TCGA;ICGC;COSMIC	20.673	Up-regulation
TK_Src_SrcA_SRC_Y	Q9UPT8	ZC3H4	P12931	SRC	Y204	Y201C	201	Missense	distal	-3	no	21.334	19.533	EPSD	TCGA;ICGC;COSMIC	20.673	Loss
TK_Src_SrcA_SRC_Y	Q9UPT8	ZC3H4	P12931	SRC	Y217	E223G	223	Missense	distal	6	no	23.941	23.932	EPSD	TCGA;ICGC;COSMIC	20.673	Down-regulation
TK_Src_SrcA_SRC_Y	Q9UPT8	ZC3H4	P12931	SRC	Y217	D218N	218	Missense	proximal	1	no	23.941	22.550	EPSD	TCGA;ICGC;COSMIC	20.673	Down-regulation
TK_Src_SrcA_SRC_Y	Q9UPT8	ZC3H4	P12931	SRC	Y217	D219E	219	Missense	proximal	2	no	23.941	24.229	EPSD	TCGA;ICGC;COSMIC	20.673	Up-regulation
TK_Src_SrcA_SRC_Y	Q9UPT8	ZC3H4	P12931	SRC	Y217	K222R	222	Missense	distal	5	no	23.941	23.885	EPSD	TCGA;ICGC;COSMIC	20.673	Down-regulation
TK_Src_SrcA_SRC_Y	Q9UPT8	ZC3H4	P12931	SRC	Y364	D359N	359	Missense	distal	-5	no	22.518	22.306	EPSD	TCGA;ICGC;COSMIC	20.673	Down-regulation
TK_Src_SrcA_SRC_Y	Q9UPT8	ZC3H4	P12931	SRC	Y364	M368V	368	Missense	distal	4	no	22.518	22.555	EPSD	TCGA;ICGC;COSMIC	20.673	Up-regulation
TK_Src_SrcA_SRC_Y	Q9UPT8	ZC3H4	P12931	SRC	Y364	E361K	361	Missense	distal	-3	no	22.518	20.807	EPSD	TCGA;ICGC	20.673	Down-regulation
TK_Src_SrcA_SRC_Y	Q9UPT8	ZC3H4	P12931	SRC	Y1218	R1222W	1222	Missense	distal	4	no	22.748	22.721	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	20.673	Down-regulation
TK_Src_SrcA_SRC_Y	Q9UPT8	ZC3H4	P12931	SRC	Y1218	N1219S	1219	Missense	proximal	1	no	22.748	23.648	EPSD;PhosphoSitePlus	TCGA	20.673	Up-regulation
TK_Src_SrcA_SRC_Y	Q9NWQ8	PAG1	P12931	SRC	Y163	K167N	167	Missense	distal	4	no	20.831	20.875	EPSD	TCGA;ICGC;COSMIC	20.673	Up-regulation
TK_Src_SrcA_SRC_Y	Q9NWQ8	PAG1	P12931	SRC	Y181	K188R	188	Missense	distal	7	no	22.670	22.696	EPSD	TCGA;ICGC;COSMIC;CCLE	20.673	Up-regulation
TK_Src_SrcA_SRC_Y	Q9NWQ8	PAG1	P12931	SRC	Y181	M175V	175	Missense	distal	-6	no	22.670	22.961	EPSD	TCGA;ICGC;COSMIC;GDSC;CCLE	20.673	Up-regulation
TK_Src_SrcA_SRC_Y	Q9NWQ8	PAG1	P12931	SRC	Y317	A315D	315	Missense	proximal	-2	no	20.641	21.910	PhosphoSitePlus	TCGA;ICGC	20.673	Gain
TK_Src_SrcA_SRC_Y	Q9NWQ8	PAG1	P12931	SRC	Y387	A389V	389	Missense	proximal	2	no	24.001	24.212	EPSD	TCGA;ICGC;COSMIC;GDSC;CCLE	20.673	Up-regulation
TK_Src_SrcA_SRC_Y	Q9NWQ8	PAG1	P12931	SRC	Y417	D422E	422	Missense	distal	5	no	21.965	22.172	EPSD	TCGA;ICGC;COSMIC	20.673	Up-regulation
TK_Src_SrcA_SRC_Y	Q9NWQ8	PAG1	P12931	SRC	Y417	D416N	416	Missense	proximal	-1	no	21.965	21.015	EPSD	TCGA;ICGC;COSMIC	20.673	Down-regulation
TK_Src_SrcA_SRC_Y	Q9NWQ8	PAG1	P12931	SRC	Y417	S419R	419	Missense	proximal	2	no	21.965	21.133	EPSD	TCGA	20.673	Down-regulation
TK_Src_SrcA_SRC_Y	Q9NWQ8	PAG1	P12931	SRC	Y417	D416A	416	Missense	proximal	-1	no	21.965	22.062	EPSD	TCGA	20.673	Up-regulation
TK_Src_SrcA_SRC_Y	Q16832	DDR2	P12931	SRC	Y471	R478H	478	Missense	distal	7	no	21.934	21.920	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC;CCLE	20.673	Down-regulation
TK_Src_SrcA_SRC_Y	Q16832	DDR2	P12931	SRC	Y471	S469L	469	Missense	proximal	-2	no	21.934	21.190	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	20.673	Down-regulation
TK_Src_SrcA_SRC_Y	Q16832	DDR2	P12931	SRC	Y471	R478G	478	Missense	distal	7	no	21.934	21.927	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	20.673	Down-regulation
TK_Src_SrcA_SRC_Y	Q16832	DDR2	P12931	SRC	Y471	R473H	473	Missense	proximal	2	no	21.934	21.782	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	20.673	Down-regulation
TK_Src_SrcA_SRC_Y	Q16832	DDR2	P12931	SRC	Y471	P476S	476	Missense	distal	5	no	21.934	21.757	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	20.673	Down-regulation
TK_Src_SrcA_SRC_Y	Q16832	DDR2	P12931	SRC	Y481	R478H	478	Missense	distal	-3	no	21.232	21.197	EPSD	TCGA;ICGC;COSMIC;CCLE	20.673	Down-regulation
TK_Src_SrcA_SRC_Y	Q16832	DDR2	P12931	SRC	Y481	R478G	478	Missense	distal	-3	no	21.232	22.125	EPSD	TCGA;ICGC;COSMIC	20.673	Up-regulation
TK_Src_SrcA_SRC_Y	Q16832	DDR2	P12931	SRC	Y481	P476S	476	Missense	distal	-5	no	21.232	21.334	EPSD	TCGA;ICGC;COSMIC	20.673	Up-regulation
TK_Src_SrcA_SRC_Y	Q16832	DDR2	P12931	SRC	Y521	E516Q	516	Missense	distal	-5	no	20.680	20.253	EPSD	TCGA;ICGC;COSMIC	20.673	Loss
TK_Src_SrcA_SRC_Y	Q16832	DDR2	P12931	SRC	Y521	P515H	515	Missense	distal	-6	no	20.680	20.556	EPSD	TCGA;ICGC;COSMIC	20.673	Loss
TK_Src_SrcA_SRC_Y	Q16832	DDR2	P12931	SRC	Y521	H520Q	520	Missense	proximal	-1	no	20.680	20.617	EPSD	TCGA;ICGC;COSMIC	20.673	Loss
TK_Src_SrcA_SRC_Y	Q16832	DDR2	P12931	SRC	Y740	I743V	743	Missense	distal	3	no	22.905	22.966	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	20.673	Up-regulation
TK_Src_SrcA_SRC_Y	Q16832	DDR2	P12931	SRC	Y740	G738V	738	Missense	proximal	-2	no	22.905	21.629	EPSD;PhosphoSitePlus	TCGA;ICGC	20.673	Down-regulation
TK_Src_SrcA_SRC_Y	Q16832	DDR2	P12931	SRC	Y741	I743V	743	Missense	proximal	2	no	21.636	22.831	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	20.673	Up-regulation
TK_Src_SrcA_SRC_Y	Q16832	DDR2	P12931	SRC	Y741	G738V	738	Missense	distal	-3	no	21.636	20.360	EPSD;PhosphoSitePlus	TCGA;ICGC	20.673	Loss
TK_Src_SrcA_SRC_Y	Q8N556	AFAP1	P12931	SRC	Y94	S101R	101	Missense	distal	7	no	25.289	25.327	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	20.673	Up-regulation
TK_Src_SrcA_SRC_Y	Q8N556	AFAP1	P12931	SRC	Y122	E128D	128	Missense	distal	6	no	21.756	21.706	EPSD	TCGA;ICGC;COSMIC	20.673	Down-regulation
TK_Src_SrcA_SRC_Y	Q8N556	AFAP1	P12931	SRC	Y125	E128D	128	Missense	distal	3	no	21.006	20.911	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	20.673	Down-regulation
TK_Src_SrcA_SRC_Y	Q8N556	AFAP1	P12931	SRC	Y451	T444R	444	Missense	distal	-7	no	22.849	23.001	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	20.673	Up-regulation
TK_Src_SrcA_SRC_Y	Q8N556	AFAP1	P12931	SRC	Y451	P446S	446	Missense	distal	-5	no	22.849	22.951	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	20.673	Up-regulation
TK_Src_SrcA_SRC_Y	Q8N556	AFAP1	P12931	SRC	Y491	G490V	490	Missense	proximal	-1	no	19.482	21.473	EPSD	TCGA;ICGC;COSMIC	20.673	Gain
TK_Src_SrcA_SRC_Y	Q8N556	AFAP1	P12931	SRC	Y501	A498T	498	Missense	distal	-3	no	21.075	21.270	EPSD	TCGA;ICGC;COSMIC	20.673	Up-regulation
TK_Src_SrcA_SRC_Y	Q8N556	AFAP1	P12931	SRC	Y501	P494S	494	Missense	distal	-7	no	21.075	21.196	EPSD	TCGA;ICGC;COSMIC	20.673	Up-regulation
TK_Src_SrcA_SRC_Y	Q8N556	AFAP1	P12931	SRC	Y501	D503N	503	Missense	proximal	2	no	21.075	21.288	EPSD	TCGA;ICGC;COSMIC	20.673	Up-regulation
TK_Src_SrcA_SRC_Y	Q8N556	AFAP1	P12931	SRC	Y501	G496R	496	Missense	distal	-5	no	21.075	21.059	EPSD	TCGA;ICGC	20.673	Down-regulation
TK_Src_SrcA_SRC_Y	Q96RI1	NR1H4	P12931	SRC	Y77	S74L	74	Missense	distal	-3	no	22.496	20.228	PhosphoSitePlus	TCGA;COSMIC	20.673	Loss
TK_Src_SrcA_SRC_Y	Q96RI1	NR1H4	P12931	SRC	Y77	P84T	84	Missense	distal	7	no	22.496	22.446	PhosphoSitePlus	TCGA;COSMIC	20.673	Down-regulation
TK_Src_SrcA_SRC_Y	Q96RI1	NR1H4	P12931	SRC	Y77	S72F	72	Missense	distal	-5	no	22.496	22.173	PhosphoSitePlus	TCGA;COSMIC	20.673	Down-regulation
TK_Src_SrcA_SRC_Y	Q13322	GRB10	P12931	SRC	Y16	Q22K	22	Missense	distal	6	no	20.861	20.877	EPSD	TCGA;ICGC;COSMIC	20.673	Up-regulation
TK_Src_SrcA_SRC_Y	Q13322	GRB10	P12931	SRC	Y16	T23I	23	Missense	distal	7	no	20.861	20.931	EPSD	TCGA;ICGC;COSMIC	20.673	Up-regulation
TK_Src_SrcA_SRC_Y	Q13322	GRB10	P12931	SRC	Y16	P14L	14	Missense	proximal	-2	no	20.861	19.331	EPSD	TCGA;ICGC;COSMIC;GDSC;CCLE	20.673	Loss
TK_Src_SrcA_SRC_Y	Q13435	SF3B2	P12931	SRC	Y379	E380K	380	Missense	proximal	1	no	24.933	22.538	PhosphoSitePlus;EPSD	TCGA;ICGC;COSMIC	20.673	Down-regulation
TK_Src_SrcA_SRC_Y	Q13435	SF3B2	P12931	SRC	Y591	E598K	598	Missense	distal	7	no	23.212	23.216	EPSD	TCGA;ICGC;COSMIC	20.673	Up-regulation
TK_Src_SrcA_SRC_Y	Q13435	SF3B2	P12931	SRC	Y645	P643T	643	Missense	proximal	-2	no	20.833	19.809	EPSD	TCGA;ICGC	20.673	Loss
TK_Src_SrcA_SRC_Y	Q13435	SF3B2	P12931	SRC	Y645	P651S	651	Missense	distal	6	no	20.833	20.817	EPSD	TCGA;ICGC;COSMIC	20.673	Down-regulation
TK_Src_SrcA_SRC_Y	Q13435	SF3B2	P12931	SRC	Y806	T810M	810	Missense	distal	4	no	21.090	21.032	EPSD	TCGA;COSMIC	20.673	Down-regulation
TK_Src_SrcA_SRC_Y	Q13435	SF3B2	P12931	SRC	Y806	M799I	799	Missense	distal	-7	no	21.090	21.376	EPSD	TCGA;COSMIC	20.673	Up-regulation
TK_Src_SrcA_SRC_Y	Q9NYF8	BCLAF1	P12931	SRC	Y81	G77C	77	Missense	distal	-4	no	22.817	21.200	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	20.673	Down-regulation
TK_Src_SrcA_SRC_Y	Q9NYF8	BCLAF1	P12931	SRC	Y81	G84E	84	Missense	distal	3	no	22.817	22.539	EPSD;PhosphoSitePlus	TCGA;COSMIC	20.673	Down-regulation
TK_Src_SrcA_SRC_Y	Q9NYF8	BCLAF1	P12931	SRC	Y81	G83E	83	Missense	proximal	2	no	22.817	23.772	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	20.673	Up-regulation
TK_Src_SrcA_SRC_Y	Q9NYF8	BCLAF1	P12931	SRC	Y81	R76K	76	Missense	distal	-5	no	22.817	22.509	EPSD;PhosphoSitePlus	TCGA;COSMIC	20.673	Down-regulation
TK_Src_SrcA_SRC_Y	Q9NYF8	BCLAF1	P12931	SRC	Y81	G83R	83	Missense	proximal	2	no	22.817	23.114	EPSD;PhosphoSitePlus	TCGA;COSMIC	20.673	Up-regulation
TK_Src_SrcA_SRC_Y	Q9NYF8	BCLAF1	P12931	SRC	Y81	Y80H	80	Missense	proximal	-1	no	22.817	22.222	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	20.673	Down-regulation
TK_Src_SrcA_SRC_Y	Q9NYF8	BCLAF1	P12931	SRC	Y133	R131P	131	Missense	proximal	-2	no	19.719	21.251	EPSD	TCGA;ICGC;COSMIC	20.673	Gain
TK_Src_SrcA_SRC_Y	Q9NYF8	BCLAF1	P12931	SRC	Y150	S148Y	148	Missense	proximal	-2	no	21.992	21.445	EPSD;PhosphoSitePlus	TCGA;COSMIC	20.673	Down-regulation
TK_Src_SrcA_SRC_Y	Q9NYF8	BCLAF1	P12931	SRC	Y150	S147L	147	Missense	distal	-3	no	21.992	19.724	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	20.673	Loss
TK_Src_SrcA_SRC_Y	Q9NYF8	BCLAF1	P12931	SRC	Y150	Y150H	150	Missense	central	0	yes	21.992	0.000	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC;GDSC;CCLE	20.673	Loss
TK_Src_SrcA_SRC_Y	Q9NYF8	BCLAF1	P12931	SRC	Y150	R145C	145	Missense	distal	-5	no	21.992	21.272	EPSD;PhosphoSitePlus	TCGA;COSMIC;CCLE	20.673	Down-regulation
TK_Src_SrcA_SRC_Y	Q9NYF8	BCLAF1	P12931	SRC	Y150	K152R	152	Missense	proximal	2	no	21.992	22.504	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	20.673	Up-regulation
TK_Src_SrcA_SRC_Y	Q9NYF8	BCLAF1	P12931	SRC	Y150	S144A	144	Missense	distal	-6	no	21.992	21.902	EPSD;PhosphoSitePlus	TCGA;COSMIC	20.673	Down-regulation
TK_Src_SrcA_SRC_Y	Q9NYF8	BCLAF1	P12931	SRC	Y150	P154L	154	Missense	distal	4	no	21.992	22.021	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	20.673	Up-regulation
TK_Src_SrcA_SRC_Y	Q9NYF8	BCLAF1	P12931	SRC	Y150	P149L	149	Missense	proximal	-1	no	21.992	21.978	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	20.673	Down-regulation
TK_Src_SrcA_SRC_Y	Q9NYF8	BCLAF1	P12931	SRC	Y150	S151N	151	Missense	proximal	1	no	21.992	21.093	EPSD;PhosphoSitePlus	TCGA	20.673	Down-regulation
TK_Src_SrcA_SRC_Y	Q9NYF8	BCLAF1	P12931	SRC	Y284	Y284C	284	Missense	central	0	yes	20.774	0.000	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	20.673	Loss
TK_Src_SrcA_SRC_Y	Q9NYF8	BCLAF1	P12931	SRC	Y284	N279I	279	Missense	distal	-5	no	20.774	20.596	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	20.673	Loss
TK_Src_SrcA_SRC_Y	Q9NYF8	BCLAF1	P12931	SRC	Y284	R283Q	283	Missense	proximal	-1	no	20.774	22.606	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	20.673	Up-regulation
TK_Src_SrcA_SRC_Y	Q9NYF8	BCLAF1	P12931	SRC	Y408	Q410K	410	Missense	proximal	2	no	21.959	21.098	EPSD;PhosphoSitePlus	TCGA;COSMIC	20.673	Down-regulation
TK_Src_SrcA_SRC_Y	Q9NYF8	BCLAF1	P12931	SRC	Y408	D401A	401	Missense	distal	-7	no	21.959	21.586	EPSD;PhosphoSitePlus	TCGA;COSMIC	20.673	Down-regulation
TK_Src_SrcA_SRC_Y	Q9NYF8	BCLAF1	P12931	SRC	Y733	K734T	734	Missense	proximal	1	no	20.434	21.077	EPSD	TCGA;COSMIC	20.673	Gain
TK_Src_SrcA_SRC_Y	O15530	PDPK1	P12931	SRC	Y248	V249I	249	Missense	proximal	1	no	22.781	22.121	EPSD	TCGA;COSMIC	20.673	Down-regulation
TK_Src_SrcA_SRC_Y	O15530	PDPK1	P12931	SRC	Y485	P489S	489	Missense	distal	4	no	21.125	21.146	EPSD	TCGA;COSMIC	20.673	Up-regulation
TK_Src_SrcA_SRC_Y	O15530	PDPK1	P12931	SRC	Y486	P489S	489	Missense	distal	3	no	21.574	20.835	EPSD	TCGA;COSMIC	20.673	Down-regulation
TK_Src_SrcA_SRC_Y	O15530	PDPK1	P12931	SRC	Y486	V493L	493	Missense	distal	7	no	21.574	21.522	EPSD	TCGA;COSMIC	20.673	Down-regulation
TK_Src_SrcA_SRC_Y	Q15654	TRIP6	P12931	SRC	Y123	R120P	120	Missense	distal	-3	no	23.813	23.769	EPSD	TCGA;ICGC;COSMIC	20.673	Down-regulation
TK_Src_SrcA_SRC_Y	Q9Y613	FHOD1	P12931	SRC	Y99	G97S	97	Missense	proximal	-2	no	22.246	21.633	PhosphoSitePlus	TCGA;ICGC;COSMIC	20.673	Down-regulation
TK_Src_SrcA_SRC_Y	Q9Y613	FHOD1	P12931	SRC	Y99	R92Q	92	Missense	distal	-7	no	22.246	22.021	PhosphoSitePlus	TCGA;ICGC;COSMIC	20.673	Down-regulation
TK_Src_SrcA_SRC_Y	Q9Y613	FHOD1	P12931	SRC	Y176	L181F	181	Missense	distal	5	no	20.923	20.981	EPSD	TCGA;ICGC;COSMIC	20.673	Up-regulation
TK_Src_SrcA_SRC_Y	Q9Y613	FHOD1	P12931	SRC	Y439	E435K	435	Missense	distal	-4	no	20.937	19.767	EPSD	TCGA;ICGC;COSMIC	20.673	Loss
TK_Src_SrcA_SRC_Y	Q9Y613	FHOD1	P12931	SRC	Y878	S875C	875	Missense	distal	-3	no	23.528	20.806	EPSD	TCGA;ICGC;COSMIC	20.673	Down-regulation
TK_Src_SrcA_SRC_Y	Q9Y613	FHOD1	P12931	SRC	Y878	P872R	872	Missense	distal	-6	no	23.528	23.437	EPSD	TCGA;ICGC;COSMIC	20.673	Down-regulation
TK_Src_SrcA_SRC_Y	Q9Y613	FHOD1	P12931	SRC	Y878	S875F	875	Missense	distal	-3	no	23.528	20.934	EPSD	TCGA;ICGC;COSMIC	20.673	Down-regulation
TK_Src_SrcA_SRC_Y	P00533	EGFR	P12931	SRC	Y112	E114K	114	Missense	proximal	2	no	22.347	21.178	EPSD	TCGA;ICGC;COSMIC	20.673	Down-regulation
TK_Src_SrcA_SRC_Y	P00533	EGFR	P12931	SRC	Y112	R108K	108	Missense	distal	-4	no	22.347	21.629	EPSD	TCGA;ICGC;COSMIC;GDSC;CCLE	20.673	Down-regulation
TK_Src_SrcA_SRC_Y	P00533	EGFR	P12931	SRC	Y112	R108G	108	Missense	distal	-4	no	22.347	22.366	EPSD	TCGA;ICGC;COSMIC	20.673	Up-regulation
TK_Src_SrcA_SRC_Y	P00533	EGFR	P12931	SRC	Y112	S116F	116	Missense	distal	4	no	22.347	22.337	EPSD	TCGA;ICGC;COSMIC	20.673	Down-regulation
TK_Src_SrcA_SRC_Y	P00533	EGFR	P12931	SRC	Y113	E114K	114	Missense	proximal	1	no	21.380	18.986	EPSD	TCGA;ICGC;COSMIC	20.673	Loss
TK_Src_SrcA_SRC_Y	P00533	EGFR	P12931	SRC	Y113	R108K	108	Missense	distal	-5	no	21.380	21.072	EPSD	TCGA;ICGC;COSMIC;GDSC;CCLE	20.673	Down-regulation
TK_Src_SrcA_SRC_Y	P00533	EGFR	P12931	SRC	Y113	R108G	108	Missense	distal	-5	no	21.380	21.396	EPSD	TCGA;ICGC;COSMIC	20.673	Up-regulation
TK_Src_SrcA_SRC_Y	P00533	EGFR	P12931	SRC	Y113	S116F	116	Missense	distal	3	no	21.380	22.262	EPSD	TCGA;ICGC;COSMIC	20.673	Up-regulation
TK_Src_SrcA_SRC_Y	P00533	EGFR	P12931	SRC	Y764	S768I	768	Missense	distal	4	no	23.344	23.326	EPSD;PhosphoSitePlus	TCGA;COSMIC;GDSC;CCLE	20.673	Down-regulation
TK_Src_SrcA_SRC_Y	P00533	EGFR	P12931	SRC	Y764	I759N	759	Missense	distal	-5	no	23.344	23.521	EPSD;PhosphoSitePlus	TCGA;COSMIC	20.673	Up-regulation
TK_Src_SrcA_SRC_Y	P00533	EGFR	P12931	SRC	Y764	V769L	769	Missense	distal	5	no	23.344	23.439	EPSD;PhosphoSitePlus	TCGA;COSMIC	20.673	Up-regulation
TK_Src_SrcA_SRC_Y	P00533	EGFR	P12931	SRC	Y869	E872G	872	Missense	distal	3	no	21.933	22.211	EPSD;PhosphoSitePlus	TCGA;COSMIC	20.673	Up-regulation
TK_Src_SrcA_SRC_Y	P00533	EGFR	P12931	SRC	Y869	E866K	866	Missense	distal	-3	no	21.933	20.222	EPSD;PhosphoSitePlus	TCGA;COSMIC	20.673	Loss
TK_Src_SrcA_SRC_Y	P00533	EGFR	P12931	SRC	Y869	A864V	864	Missense	distal	-5	no	21.933	21.934	EPSD;PhosphoSitePlus	TCGA;COSMIC;GDSC	20.673	Up-regulation
TK_Src_SrcA_SRC_Y	P00533	EGFR	P12931	SRC	Y915	G917R	917	Missense	proximal	2	no	20.564	20.861	EPSD;PhosphoSitePlus	TCGA;COSMIC;GDSC	20.673	Gain
TK_Src_SrcA_SRC_Y	P00533	EGFR	P12931	SRC	Y915	G917A	917	Missense	proximal	2	no	20.564	21.340	EPSD;PhosphoSitePlus	TCGA;COSMIC	20.673	Gain
TK_Src_SrcA_SRC_Y	P00533	EGFR	P12931	SRC	Y978	R977H	977	Missense	proximal	-1	no	20.188	22.083	EPSD	TCGA;COSMIC	20.673	Gain
TK_Src_SrcA_SRC_Y	P00533	EGFR	P12931	SRC	Y998	A1000V	1000	Missense	proximal	2	no	22.476	22.686	EPSD	TCGA;COSMIC	20.673	Up-regulation
TK_Src_SrcA_SRC_Y	P00533	EGFR	P12931	SRC	Y998	F997V	997	Missense	proximal	-1	no	22.476	24.445	EPSD	TCGA;COSMIC	20.673	Up-regulation
TK_Src_SrcA_SRC_Y	P00533	EGFR	P12931	SRC	Y1016	P1019L	1019	Missense	distal	3	no	20.800	20.702	PhosphoSitePlus;EPSD	TCGA;COSMIC	20.673	Down-regulation
TK_Src_SrcA_SRC_Y	P00533	EGFR	P12931	SRC	Y1016	D1009N	1009	Missense	distal	-7	no	20.800	20.719	PhosphoSitePlus;EPSD	TCGA;COSMIC	20.673	Down-regulation
TK_Src_SrcA_SRC_Y	P00533	EGFR	P12931	SRC	Y1125	P1123S	1123	Missense	proximal	-2	no	24.203	23.417	EPSD;PhosphoSitePlus	TCGA;ICGC	20.673	Down-regulation
TK_Src_SrcA_SRC_Y	P00533	EGFR	P12931	SRC	Y1172	P1178L	1178	Missense	distal	6	no	22.551	22.567	EPSD	TCGA;ICGC;COSMIC	20.673	Up-regulation
TK_Src_SrcA_SRC_Y	P00533	EGFR	P12931	SRC	Y1172	L1167M	1167	Missense	distal	-5	no	22.551	22.394	EPSD	TCGA;ICGC;COSMIC	20.673	Down-regulation
TK_Src_SrcA_SRC_Y	P16662	UGT2B7	P12931	SRC	Y438	V432L	432	Missense	distal	-6	no	22.427	22.608	PhosphoSitePlus	TCGA;ICGC;COSMIC	20.673	Up-regulation
TK_Src_SrcA_SRC_Y	P16662	UGT2B7	P12931	SRC	Y438	D435N	435	Missense	distal	-3	no	22.427	21.919	PhosphoSitePlus	TCGA;ICGC;COSMIC	20.673	Down-regulation
TK_Src_SrcA_SRC_Y	P16662	UGT2B7	P12931	SRC	Y438	V442G	442	Missense	distal	4	no	22.427	22.431	PhosphoSitePlus	TCGA;ICGC	20.673	Up-regulation
TK_Src_SrcA_SRC_Y	P16662	UGT2B7	P12931	SRC	Y438	S437L	437	Missense	proximal	-1	no	22.427	22.765	PhosphoSitePlus	TCGA;ICGC;COSMIC	20.673	Up-regulation
TK_Src_SrcA_SRC_Y	Q15691	MAPRE1	P12931	SRC	Y124	A117T	117	Missense	distal	-7	no	20.498	20.918	EPSD	TCGA;ICGC;COSMIC	20.673	Gain
TK_Src_SrcA_SRC_Y	P12931	SRC	P12931	SRC	Y338	V340L	340	Missense	proximal	2	no	23.077	22.154	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	20.673	Down-regulation
TK_Src_SrcA_SRC_Y	P12931	SRC	P12931	SRC	Y338	E342K	342	Missense	distal	4	no	23.077	23.078	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	20.673	Up-regulation
TK_Src_SrcA_SRC_Y	P12931	SRC	P12931	SRC	Y419	A425V	425	Missense	distal	6	no	24.549	24.558	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC;CCLE	20.673	Up-regulation
TK_Src_SrcA_SRC_Y	P33151	CDH5	P12931	SRC	Y658	D659N	659	Missense	proximal	1	no	20.985	19.593	EPSD;PhosphoSitePlus	TCGA;COSMIC	20.673	Loss
TK_Src_SrcA_SRC_Y	P33151	CDH5	P12931	SRC	Y685	A686V	686	Missense	proximal	1	no	21.644	21.059	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	20.673	Down-regulation
TK_Src_SrcA_SRC_Y	P33151	CDH5	P12931	SRC	Y725	D726E	726	Missense	proximal	1	no	24.899	25.505	EPSD	TCGA;ICGC;COSMIC	20.673	Up-regulation
TK_Src_SrcA_SRC_Y	P33151	CDH5	P12931	SRC	Y725	G732C	732	Missense	distal	7	no	24.899	24.978	EPSD	TCGA;ICGC;COSMIC	20.673	Up-regulation
TK_Src_SrcA_SRC_Y	P33151	CDH5	P12931	SRC	Y725	G732S	732	Missense	distal	7	no	24.899	24.868	EPSD	TCGA;ICGC;COSMIC	20.673	Down-regulation
TK_Src_SrcA_SRC_Y	P33151	CDH5	P12931	SRC	Y725	P724L	724	Missense	proximal	-1	no	24.899	24.885	EPSD	TCGA;COSMIC	20.673	Down-regulation
TK_Src_SrcA_SRC_Y	P33151	CDH5	P12931	SRC	Y725	D719N	719	Missense	distal	-6	no	24.899	24.709	EPSD	TCGA	20.673	Down-regulation
TK_Src_SrcA_SRC_Y	P33151	CDH5	P12931	SRC	Y731	D726E	726	Missense	distal	-5	no	21.971	22.071	PhosphoSitePlus;EPSD	TCGA;ICGC;COSMIC	20.673	Up-regulation
TK_Src_SrcA_SRC_Y	P33151	CDH5	P12931	SRC	Y731	G732C	732	Missense	proximal	1	no	21.971	19.674	PhosphoSitePlus;EPSD	TCGA;ICGC;COSMIC	20.673	Loss
TK_Src_SrcA_SRC_Y	P33151	CDH5	P12931	SRC	Y731	G732S	732	Missense	proximal	1	no	21.971	21.856	PhosphoSitePlus;EPSD	TCGA;ICGC;COSMIC	20.673	Down-regulation
TK_Src_SrcA_SRC_Y	P33151	CDH5	P12931	SRC	Y731	P724L	724	Missense	distal	-7	no	21.971	21.856	PhosphoSitePlus;EPSD	TCGA;COSMIC	20.673	Down-regulation
TK_Src_SrcA_SRC_Y	P33151	CDH5	P12931	SRC	Y731	S736Y	736	Missense	distal	5	no	21.971	22.384	PhosphoSitePlus;EPSD	TCGA;ICGC	20.673	Up-regulation
TK_Src_SrcA_SRC_Y	Q92556	ELMO1	P12931	SRC	Y140	R139Q	139	Missense	proximal	-1	no	19.398	21.230	EPSD	TCGA;ICGC;COSMIC;GDSC;CCLE	20.673	Gain
TK_Src_SrcA_SRC_Y	Q92556	ELMO1	P12931	SRC	Y216	S212N	212	Missense	distal	-4	no	20.326	20.740	EPSD	TCGA;ICGC;COSMIC	20.673	Gain
TK_Src_SrcA_SRC_Y	Q92556	ELMO1	P12931	SRC	Y395	A388T	388	Missense	distal	-7	no	20.907	21.327	EPSD	TCGA;ICGC;COSMIC	20.673	Up-regulation
TK_Src_SrcA_SRC_Y	Q92556	ELMO1	P12931	SRC	Y395	E401D	401	Missense	distal	6	no	20.907	20.857	EPSD	TCGA;ICGC;COSMIC	20.673	Down-regulation
TK_Src_SrcA_SRC_Y	Q92556	ELMO1	P12931	SRC	Y395	H391N	391	Missense	distal	-4	no	20.907	21.536	EPSD	TCGA;ICGC;COSMIC	20.673	Up-regulation
TK_Src_SrcA_SRC_Y	Q92556	ELMO1	P12931	SRC	Y395	Q392K	392	Missense	distal	-3	no	20.907	20.076	EPSD	TCGA;ICGC;COSMIC	20.673	Loss
TK_Src_SrcA_SRC_Y	Q92556	ELMO1	P12931	SRC	Y511	R518C	518	Missense	distal	7	no	20.767	20.839	EPSD	TCGA;COSMIC	20.673	Up-regulation
TK_Src_SrcA_SRC_Y	Q92556	ELMO1	P12931	SRC	Y511	T512N	512	Missense	proximal	1	no	20.767	20.521	EPSD	TCGA;ICGC;COSMIC	20.673	Loss
TK_Src_SrcA_SRC_Y	Q92556	ELMO1	P12931	SRC	Y511	E513K	513	Missense	proximal	2	no	20.767	19.597	EPSD	TCGA;ICGC;COSMIC	20.673	Loss
TK_Src_SrcA_SRC_Y	Q92556	ELMO1	P12931	SRC	Y511	E513Q	513	Missense	proximal	2	no	20.767	20.458	EPSD	TCGA;ICGC;COSMIC	20.673	Loss
TK_Src_SrcA_SRC_Y	Q92556	ELMO1	P12931	SRC	Y511	R518H	518	Missense	distal	7	no	20.767	20.753	EPSD	TCGA	20.673	Down-regulation
TK_Src_SrcA_SRC_Y	Q92556	ELMO1	P12931	SRC	Y724	D725H	725	Missense	proximal	1	no	20.794	19.349	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC;CCLE	20.673	Loss
TK_Src_SrcA_SRC_Y	P32004	L1CAM	P12931	SRC	Y589	E596V	596	Missense	distal	7	no	21.043	21.101	EPSD	TCGA;COSMIC	20.673	Up-regulation
TK_Src_SrcA_SRC_Y	P32004	L1CAM	P12931	SRC	Y589	E596K	596	Missense	distal	7	no	21.043	21.047	EPSD	TCGA;COSMIC;GDSC;CCLE	20.673	Up-regulation
TK_Src_SrcA_SRC_Y	P32004	L1CAM	P12931	SRC	Y589	D585N	585	Missense	distal	-4	no	21.043	20.511	EPSD	TCGA;COSMIC	20.673	Loss
TK_Src_SrcA_SRC_Y	P32004	L1CAM	P12931	SRC	Y589	S590N	590	Missense	proximal	1	no	21.043	20.144	EPSD	TCGA;COSMIC;GDSC;CCLE	20.673	Loss
TK_Src_SrcA_SRC_Y	P32004	L1CAM	P12931	SRC	Y811	P812S	812	Missense	proximal	1	no	18.897	21.042	EPSD	TCGA	20.673	Gain
TK_Src_SrcA_SRC_Y	P46934	NEDD4	P12931	SRC	Y412	S408Y	408	Missense	distal	-4	no	20.940	20.894	EPSD	TCGA;ICGC;COSMIC	20.673	Down-regulation
TK_Src_SrcA_SRC_Y	P29350	PTPN6	P12931	SRC	Y61	D59N	59	Missense	proximal	-2	no	20.996	20.716	EPSD	TCGA;COSMIC	20.673	Down-regulation
TK_Src_SrcA_SRC_Y	P29350	PTPN6	P12931	SRC	Y214	T216M	216	Missense	proximal	2	no	21.100	20.952	EPSD	TCGA;COSMIC	20.673	Down-regulation
TK_Src_SrcA_SRC_Y	P29350	PTPN6	P12931	SRC	Y214	A220V	220	Missense	distal	6	no	21.100	21.110	EPSD	TCGA	20.673	Up-regulation
TK_Src_SrcA_SRC_Y	P29350	PTPN6	P12931	SRC	Y564	E561Q	561	Missense	distal	-3	no	25.378	24.498	PhosphoSitePlus;EPSD	TCGA;ICGC;COSMIC	20.673	Down-regulation
TK_Src_SrcA_SRC_Y	Q05397	PTK2	P12931	SRC	Y194	V201I	201	Missense	distal	7	no	20.702	20.676	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	20.673	Down-regulation
TK_Src_SrcA_SRC_Y	Q05397	PTK2	P12931	SRC	Y397	E403K	403	Missense	distal	6	no	21.314	21.312	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	20.673	Down-regulation
TK_Src_SrcA_SRC_Y	Q05397	PTK2	P12931	SRC	Y397	D395Y	395	Missense	proximal	-2	no	21.314	19.864	EPSD;PhosphoSitePlus	TCGA;ICGC	20.673	Loss
TK_Src_SrcA_SRC_Y	Q05397	PTK2	P12931	SRC	Y397	E404G	404	Missense	distal	7	no	21.314	21.338	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	20.673	Up-regulation
TK_Src_SrcA_SRC_Y	Q05397	PTK2	P12931	SRC	Y407	E403K	403	Missense	distal	-4	no	23.970	22.800	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	20.673	Down-regulation
TK_Src_SrcA_SRC_Y	Q05397	PTK2	P12931	SRC	Y407	E404G	404	Missense	distal	-3	no	23.970	23.367	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	20.673	Down-regulation
TK_Src_SrcA_SRC_Y	Q05397	PTK2	P12931	SRC	Y441	A448T	448	Missense	distal	7	no	21.321	21.301	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	20.673	Down-regulation
TK_Src_SrcA_SRC_Y	Q05397	PTK2	P12931	SRC	Y441	V436I	436	Missense	distal	-5	no	21.321	21.112	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	20.673	Down-regulation
TK_Src_SrcA_SRC_Y	Q05397	PTK2	P12931	SRC	Y441	A448D	448	Missense	distal	7	no	21.321	21.301	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	20.673	Down-regulation
TK_Src_SrcA_SRC_Y	Q05397	PTK2	P12931	SRC	Y861	I860M	860	Missense	proximal	-1	no	23.332	22.100	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	20.673	Down-regulation
TK_Src_SrcA_SRC_Y	Q05397	PTK2	P12931	SRC	Y861	P867S	867	Missense	distal	6	no	23.332	23.316	EPSD;PhosphoSitePlus	TCGA;ICGC	20.673	Down-regulation
TK_Src_SrcA_SRC_Y	Q05397	PTK2	P12931	SRC	Y861	H859R	859	Missense	proximal	-2	no	23.332	22.466	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	20.673	Down-regulation
TK_Src_SrcA_SRC_Y	P30304	CDC25A	P12931	SRC	Y486	R487W	487	Missense	proximal	1	no	21.860	21.776	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	20.673	Down-regulation
TK_Src_SrcA_SRC_Y	P30304	CDC25A	P12931	SRC	Y486	E492K	492	Missense	distal	6	no	21.860	21.858	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	20.673	Down-regulation
TK_Src_SrcA_SRC_Y	P07355	ANXA2	P12931	SRC	Y24	K28M	28	Missense	distal	4	no	22.045	21.991	PhosphoSitePlus	TCGA;COSMIC	20.673	Down-regulation
TK_Src_SrcA_SRC_Y	P07355	ANXA2	P12931	SRC	Y188	G183C	183	Missense	distal	-5	no	21.347	20.612	EPSD	TCGA;COSMIC	20.673	Loss
TK_Src_SrcA_SRC_Y	O75604	USP2	P12931	SRC	Y228	R229Q	229	Missense	proximal	1	no	20.069	21.061	EPSD	TCGA;ICGC;COSMIC	20.673	Gain
TK_Src_SrcA_SRC_Y	P35228	NOS2	P12931	SRC	Y46	D42G	42	Missense	distal	-4	no	20.974	20.315	EPSD	TCGA;ICGC;COSMIC	20.673	Loss
TK_Src_SrcA_SRC_Y	P35228	NOS2	P12931	SRC	Y151	E145K	145	Missense	distal	-6	no	22.633	22.621	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC;GDSC;CCLE	20.673	Down-regulation
TK_Src_SrcA_SRC_Y	P35228	NOS2	P12931	SRC	Y151	E156Q	156	Missense	distal	5	no	22.633	22.634	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	20.673	Up-regulation
TK_Src_SrcA_SRC_Y	P35228	NOS2	P12931	SRC	Y151	K155T	155	Missense	distal	4	no	22.633	22.638	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	20.673	Up-regulation
TK_Src_SrcA_SRC_Y	P35228	NOS2	P12931	SRC	Y1055	R1061W	1061	Missense	distal	6	no	20.639	20.741	PhosphoSitePlus;EPSD	TCGA;ICGC;COSMIC	20.673	Gain
TK_Src_SrcA_SRC_Y	P35228	NOS2	P12931	SRC	Y1055	G1050D	1050	Missense	distal	-5	no	20.639	20.791	PhosphoSitePlus;EPSD	TCGA;ICGC;COSMIC	20.673	Gain
TK_Src_SrcA_SRC_Y	P35228	NOS2	P12931	SRC	Y1123	R1122H	1122	Missense	proximal	-1	no	19.538	21.434	EPSD	TCGA;ICGC;COSMIC	20.673	Gain
TK_Src_SrcA_SRC_Y	P35228	NOS2	P12931	SRC	Y1123	R1122C	1122	Missense	proximal	-1	no	19.538	20.960	EPSD	TCGA;ICGC;COSMIC	20.673	Gain
TK_Src_SrcA_SRC_Y	O43490	PROM1	P12931	SRC	Y828	R821Q	821	Missense	distal	-7	no	22.681	22.456	EPSD;PhosphoSitePlus	TCGA;COSMIC	20.673	Down-regulation
TK_Src_SrcA_SRC_Y	P35579	MYH9	P12931	SRC	Y1408	A1407V	1407	Missense	proximal	-1	no	19.578	20.915	EPSD	TCGA;ICGC;COSMIC	20.673	Gain
TK_Src_SrcA_SRC_Y	P35579	MYH9	P12931	SRC	Y1861	Q1864P	1864	Missense	distal	3	no	20.211	21.585	EPSD	TCGA;ICGC;COSMIC	20.673	Gain
TK_Src_SrcA_SRC_Y	Q9BZL6	PRKD2	P12931	SRC	Y717	A716T	716	Missense	proximal	-1	no	21.371	21.354	EPSD	TCGA;COSMIC	20.673	Down-regulation
TK_Src_SrcA_SRC_Y	Q9BZL6	PRKD2	P12931	SRC	Y717	P715S	715	Missense	proximal	-2	no	21.371	20.585	EPSD	TCGA;COSMIC	20.673	Loss
TK_Src_SrcA_SRC_Y	Q9BZL6	PRKD2	P12931	SRC	Y717	E721K	721	Missense	distal	4	no	21.371	21.372	EPSD	TCGA;COSMIC	20.673	Up-regulation
TK_Src_SrcA_SRC_Y	Q9BXP5	SRRT	P12931	SRC	Y8	D5N	5	Missense	distal	-3	no	21.784	21.276	EPSD	TCGA;ICGC;COSMIC	20.673	Down-regulation
TK_Src_SrcA_SRC_Y	Q9BXP5	SRRT	P12931	SRC	Y8	R13M	13	Missense	distal	5	no	21.784	22.150	EPSD	TCGA;ICGC;CCLE	20.673	Up-regulation
TK_Src_SrcA_SRC_Y	Q9BXP5	SRRT	P12931	SRC	Y8	D6N	6	Missense	proximal	-2	no	21.784	21.504	EPSD	TCGA;ICGC;COSMIC	20.673	Down-regulation
TK_Src_SrcA_SRC_Y	Q9BXP5	SRRT	P12931	SRC	Y23	R17K	17	Missense	distal	-6	no	21.701	21.915	EPSD	TCGA;ICGC;COSMIC;GDSC;CCLE	20.673	Up-regulation
TK_Src_SrcA_SRC_Y	Q9BXP5	SRRT	P12931	SRC	Y23	Y23N	23	Missense	central	0	yes	21.701	0.000	EPSD	TCGA;ICGC;COSMIC	20.673	Loss
TK_Src_SrcA_SRC_Y	Q9BXP5	SRRT	P12931	SRC	Y55	R62W	62	Missense	distal	7	no	22.374	22.470	EPSD	TCGA;ICGC;COSMIC	20.673	Up-regulation
TK_Src_SrcA_SRC_Y	Q9BXP5	SRRT	P12931	SRC	Y55	R49H	49	Missense	distal	-6	no	22.374	22.341	EPSD	TCGA;ICGC;COSMIC;CCLE	20.673	Down-regulation
TK_Src_SrcA_SRC_Y	Q9BXP5	SRRT	P12931	SRC	Y55	R56Q	56	Missense	proximal	1	no	22.374	23.366	EPSD	TCGA;ICGC;COSMIC;CCLE	20.673	Up-regulation
TK_Src_SrcA_SRC_Y	Q9BXP5	SRRT	P12931	SRC	Y58	R62W	62	Missense	distal	4	no	21.327	21.300	EPSD	TCGA;ICGC;COSMIC	20.673	Down-regulation
TK_Src_SrcA_SRC_Y	Q9BXP5	SRRT	P12931	SRC	Y58	R56Q	56	Missense	proximal	-2	no	21.327	22.073	EPSD	TCGA;ICGC;COSMIC;CCLE	20.673	Up-regulation
TK_Src_SrcA_SRC_Y	Q96TC7	RMDN3	P12931	SRC	Y176	S172G	172	Missense	distal	-4	no	21.241	21.529	PhosphoSitePlus	TCGA;ICGC;COSMIC	20.673	Up-regulation
TK_Src_SrcA_SRC_Y	P04626	ERBB2	P12931	SRC	Y772	D769N	769	Missense	distal	-3	no	22.817	22.309	EPSD	TCGA;COSMIC	20.673	Down-regulation
TK_Src_SrcA_SRC_Y	P04626	ERBB2	P12931	SRC	Y772	V777L	777	Missense	distal	5	no	22.817	22.912	EPSD	TCGA;COSMIC	20.673	Up-regulation
TK_Src_SrcA_SRC_Y	P04626	ERBB2	P12931	SRC	Y772	G776S	776	Missense	distal	4	no	22.817	22.842	EPSD	TCGA;COSMIC	20.673	Up-regulation
TK_Src_SrcA_SRC_Y	P04626	ERBB2	P12931	SRC	Y772	D769Y	769	Missense	distal	-3	no	22.817	21.428	EPSD	TCGA;COSMIC;CCLE	20.673	Down-regulation
TK_Src_SrcA_SRC_Y	P04626	ERBB2	P12931	SRC	Y772	D769H	769	Missense	distal	-3	no	22.817	21.240	EPSD	TCGA;COSMIC	20.673	Down-regulation
TK_Src_SrcA_SRC_Y	P04626	ERBB2	P12931	SRC	Y772	I767M	767	Missense	distal	-5	no	22.817	22.706	EPSD	TCGA;COSMIC	20.673	Down-regulation
TK_Src_SrcA_SRC_Y	P04626	ERBB2	P12931	SRC	Y772	I767F	767	Missense	distal	-5	no	22.817	22.799	EPSD	TCGA;COSMIC	20.673	Down-regulation
TK_Src_SrcA_SRC_Y	P04626	ERBB2	P12931	SRC	Y772	V777M	777	Missense	distal	5	no	22.817	23.111	EPSD	TCGA;COSMIC;GDSC;CCLE	20.673	Up-regulation
TK_Src_SrcA_SRC_Y	P04626	ERBB2	P12931	SRC	Y772	G776V	776	Missense	distal	4	no	22.817	22.813	EPSD	TCGA;COSMIC;GDSC;CCLE	20.673	Down-regulation
TK_Src_SrcA_SRC_Y	P04626	ERBB2	P12931	SRC	Y877	D873N	873	Missense	distal	-4	no	22.382	21.850	PhosphoSitePlus	TCGA;COSMIC	20.673	Down-regulation
TK_Src_SrcA_SRC_Y	P04626	ERBB2	P12931	SRC	Y1005	R1006C	1006	Missense	proximal	1	no	22.300	20.997	EPSD	TCGA;COSMIC	20.673	Down-regulation
TK_Src_SrcA_SRC_Y	P04626	ERBB2	P12931	SRC	Y1023	E1021Q	1021	Missense	proximal	-2	no	22.106	20.916	EPSD	TCGA;COSMIC	20.673	Down-regulation
TK_Src_SrcA_SRC_Y	P04626	ERBB2	P12931	SRC	Y1127	V1128I	1128	Missense	proximal	1	no	21.830	21.171	EPSD	TCGA;COSMIC	20.673	Down-regulation
TK_Src_SrcA_SRC_Y	P04626	ERBB2	P12931	SRC	Y1139	R1146Q	1146	Missense	distal	7	no	21.461	21.419	EPSD	TCGA;COSMIC	20.673	Down-regulation
TK_Src_SrcA_SRC_Y	P04626	ERBB2	P12931	SRC	Y1196	P1199T	1199	Missense	distal	3	no	22.534	21.883	EPSD	TCGA;COSMIC	20.673	Down-regulation
TK_Src_SrcA_SRC_Y	P04626	ERBB2	P12931	SRC	Y1221	N1219S	1219	Missense	proximal	-2	no	21.140	20.517	EPSD	TCGA;COSMIC	20.673	Loss
TK_Src_SrcA_SRC_Y	P04626	ERBB2	P12931	SRC	Y1221	S1214N	1214	Missense	distal	-7	no	21.140	21.108	EPSD	TCGA;COSMIC;CCLE	20.673	Down-regulation
TK_Src_SrcA_SRC_Y	Q14247	CTTN	P12931	SRC	Y154	S155F	155	Missense	proximal	1	no	21.047	19.170	EPSD	TCGA;ICGC;COSMIC	20.673	Loss
TK_Src_SrcA_SRC_Y	P12830	CDH1	P12931	SRC	Y753	R749W	749	Missense	distal	-4	no	23.287	21.914	EPSD	TCGA;COSMIC	20.673	Down-regulation
TK_Src_SrcA_SRC_Y	P12830	CDH1	P12931	SRC	Y753	Y754C	754	Missense	proximal	1	no	23.287	21.010	EPSD	TCGA;COSMIC	20.673	Down-regulation
TK_Src_SrcA_SRC_Y	P12830	CDH1	P12931	SRC	Y754	G761E	761	Missense	distal	7	no	22.006	21.983	PhosphoSitePlus	TCGA;COSMIC	20.673	Down-regulation
TK_Src_SrcA_SRC_Y	P12830	CDH1	P12931	SRC	Y754	R749W	749	Missense	distal	-5	no	22.006	21.341	PhosphoSitePlus	TCGA;COSMIC	20.673	Down-regulation
TK_Src_SrcA_SRC_Y	P12830	CDH1	P12931	SRC	Y754	Y754C	754	Missense	central	0	yes	22.006	0.000	PhosphoSitePlus	TCGA;COSMIC	20.673	Loss
TK_Src_SrcA_SRC_Y	P12830	CDH1	P12931	SRC	Y755	G761E	761	Missense	distal	6	no	21.893	21.902	EPSD	TCGA;COSMIC	20.673	Up-regulation
TK_Src_SrcA_SRC_Y	P12830	CDH1	P12931	SRC	Y755	R749W	749	Missense	distal	-6	no	21.893	21.625	EPSD	TCGA;COSMIC	20.673	Down-regulation
TK_Src_SrcA_SRC_Y	P12830	CDH1	P12931	SRC	Y755	Y754C	754	Missense	proximal	-1	no	21.893	20.824	EPSD	TCGA;COSMIC	20.673	Down-regulation
TK_Src_SrcA_SRC_Y	P12830	CDH1	P12931	SRC	Y827	A824V	824	Missense	distal	-3	no	23.234	22.683	EPSD	TCGA;COSMIC	20.673	Down-regulation
TK_Src_SrcA_SRC_Y	P12830	CDH1	P12931	SRC	Y859	E864K	864	Missense	distal	5	no	21.785	21.817	EPSD	TCGA;COSMIC;GDSC;CCLE	20.673	Up-regulation
TK_Src_SrcA_SRC_Y	Q9UGK3	STAP2	P12931	SRC	Y310	Q306H	306	Missense	distal	-4	no	23.487	23.382	EPSD	TCGA;ICGC	20.673	Down-regulation
TK_Src_SrcA_SRC_Y	Q9UGK3	STAP2	P12931	SRC	Y310	G317D	317	Missense	distal	7	no	23.487	23.425	EPSD	TCGA;ICGC;COSMIC;GDSC;CCLE	20.673	Down-regulation
TK_Src_SrcA_SRC_Y	Q96P31	FCRL3	P12931	SRC	Y133	T128S	128	Missense	distal	-5	no	21.037	21.346	EPSD	TCGA;ICGC;COSMIC	20.673	Up-regulation
TK_Src_SrcA_SRC_Y	Q96P31	FCRL3	P12931	SRC	Y133	N127T	127	Missense	distal	-6	no	21.037	21.012	EPSD	TCGA;ICGC;COSMIC	20.673	Down-regulation
TK_Src_SrcA_SRC_Y	Q96P31	FCRL3	P12931	SRC	Y133	K138N	138	Missense	distal	5	no	21.037	20.955	EPSD	TCGA;ICGC;COSMIC	20.673	Down-regulation
TK_Src_SrcA_SRC_Y	Q96P31	FCRL3	P12931	SRC	Y650	M644I	644	Missense	distal	-6	no	20.454	20.973	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	20.673	Gain
TK_Src_SrcA_SRC_Y	Q96P31	FCRL3	P12931	SRC	Y662	I661V	661	Missense	proximal	-1	no	21.137	21.511	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	20.673	Up-regulation
TK_Src_SrcA_SRC_Y	Q96P31	FCRL3	P12931	SRC	Y662	S658R	658	Missense	distal	-4	no	21.137	21.407	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	20.673	Up-regulation
TK_Src_SrcA_SRC_Y	Q96P31	FCRL3	P12931	SRC	Y662	N659T	659	Missense	distal	-3	no	21.137	20.466	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	20.673	Loss
TK_Src_SrcA_SRC_Y	Q96P31	FCRL3	P12931	SRC	Y692	K697M	697	Missense	distal	5	no	20.577	20.886	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	20.673	Gain
TK_Src_SrcA_SRC_Y	Q96P31	FCRL3	P12931	SRC	Y722	E715D	715	Missense	distal	-7	no	22.894	22.865	PhosphoSitePlus;EPSD	TCGA;ICGC;COSMIC	20.673	Down-regulation
TK_Src_SrcA_SRC_Y	Q96P31	FCRL3	P12931	SRC	Y722	P726L	726	Missense	distal	4	no	22.894	22.923	PhosphoSitePlus;EPSD	TCGA;COSMIC	20.673	Up-regulation
TK_Src_SrcA_SRC_Y	Q96P31	FCRL3	P12931	SRC	Y722	N724I	724	Missense	proximal	2	no	22.894	21.805	PhosphoSitePlus;EPSD	TCGA;ICGC;COSMIC	20.673	Down-regulation
TK_Src_SrcA_SRC_Y	Q96P31	FCRL3	P12931	SRC	Y722	E716Q	716	Missense	distal	-6	no	22.894	22.770	PhosphoSitePlus;EPSD	TCGA;ICGC;COSMIC	20.673	Down-regulation
TK_Src_SrcA_SRC_Y	Q96P31	FCRL3	P12931	SRC	Y722	V725A	725	Missense	distal	3	no	22.894	22.324	PhosphoSitePlus;EPSD	TCGA;COSMIC	20.673	Down-regulation
TK_Src_SrcA_SRC_Y	Q13642	FHL1	P12931	SRC	Y149	T156I	156	Missense	distal	7	no	20.765	20.834	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	20.673	Up-regulation
TK_Src_SrcA_SRC_Y	Q13642	FHL1	P12931	SRC	Y149	F148L	148	Missense	proximal	-1	no	20.765	21.624	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	20.673	Up-regulation
TK_Src_SrcA_SRC_Y	Q13642	FHL1	P12931	SRC	Y176	G172A	172	Missense	distal	-4	no	21.239	20.556	EPSD	TCGA;ICGC;COSMIC	20.673	Loss
TK_Src_SrcA_SRC_Y	Q13642	FHL1	P12931	SRC	Y207	V210M	210	Missense	distal	3	no	21.325	20.959	EPSD	TCGA;ICGC;COSMIC	20.673	Down-regulation
TK_Src_SrcA_SRC_Y	Q13642	FHL1	P12931	SRC	Y207	E204A	204	Missense	distal	-3	no	21.325	19.997	EPSD	TCGA;ICGC;COSMIC	20.673	Loss
TK_Src_SrcA_SRC_Y	Q13642	FHL1	P12931	SRC	Y207	K214N	214	Missense	distal	7	no	21.325	21.281	EPSD	TCGA;ICGC;COSMIC	20.673	Down-regulation
TK_Src_SrcA_SRC_Y	Q13642	FHL1	P12931	SRC	Y207	F200S	200	Missense	distal	-7	no	21.325	21.658	EPSD	TCGA;ICGC;COSMIC	20.673	Up-regulation
TK_Src_SrcA_SRC_Y	Q13642	FHL1	P12931	SRC	Y208	V210M	210	Missense	proximal	2	no	22.496	22.230	EPSD	TCGA;ICGC;COSMIC	20.673	Down-regulation
TK_Src_SrcA_SRC_Y	Q13642	FHL1	P12931	SRC	Y208	E204A	204	Missense	distal	-4	no	22.496	21.380	EPSD	TCGA;ICGC;COSMIC	20.673	Down-regulation
TK_Src_SrcA_SRC_Y	Q13642	FHL1	P12931	SRC	Y208	K214N	214	Missense	distal	6	no	22.496	22.451	EPSD	TCGA;ICGC;COSMIC	20.673	Down-regulation
TK_Src_SrcA_SRC_Y	P35222	CTNNB1	P12931	SRC	Y86	R90Q	90	Missense	distal	4	no	21.696	21.718	EPSD	TCGA;COSMIC	20.673	Up-regulation
TK_Src_SrcA_SRC_Y	P35222	CTNNB1	P12931	SRC	Y86	R90L	90	Missense	distal	4	no	21.696	21.730	EPSD	TCGA	20.673	Up-regulation
TK_Src_SrcA_SRC_Y	P35222	CTNNB1	P12931	SRC	Y86	G84R	84	Missense	proximal	-2	no	21.696	20.339	EPSD	TCGA;COSMIC	20.673	Loss
TK_Src_SrcA_SRC_Y	P35222	CTNNB1	P12931	SRC	Y86	A80T	80	Missense	distal	-6	no	21.696	21.734	EPSD	TCGA	20.673	Up-regulation
TK_Src_SrcA_SRC_Y	P35222	CTNNB1	P12931	SRC	Y333	E334A	334	Missense	proximal	1	no	22.219	20.922	PhosphoSitePlus;EPSD	TCGA;COSMIC	20.673	Down-regulation
TK_Src_SrcA_SRC_Y	P35222	CTNNB1	P12931	SRC	Y333	K335T	335	Missense	proximal	2	no	22.219	23.303	PhosphoSitePlus;EPSD	TCGA;COSMIC	20.673	Up-regulation
TK_Src_SrcA_SRC_Y	P35222	CTNNB1	P12931	SRC	Y333	K335I	335	Missense	proximal	2	no	22.219	22.226	PhosphoSitePlus;EPSD	TCGA;COSMIC	20.673	Up-regulation
TK_Src_SrcA_SRC_Y	P35222	CTNNB1	P12931	SRC	Y333	Y333F	333	Missense	central	0	yes	22.219	0.000	PhosphoSitePlus;EPSD	TCGA;COSMIC	20.673	Loss
TK_Src_SrcA_SRC_Y	P35222	CTNNB1	P12931	SRC	Y333	M328I	328	Missense	distal	-5	no	22.219	22.330	PhosphoSitePlus;EPSD	TCGA;COSMIC	20.673	Up-regulation
TK_Src_SrcA_SRC_Y	P35222	CTNNB1	P12931	SRC	Y333	T339N	339	Missense	distal	6	no	22.219	22.212	PhosphoSitePlus;EPSD	TCGA;COSMIC	20.673	Down-regulation
TK_Src_SrcA_SRC_Y	P35222	CTNNB1	P12931	SRC	Y333	E334K	334	Missense	proximal	1	no	22.219	19.825	PhosphoSitePlus;EPSD	TCGA;COSMIC;GDSC;CCLE	20.673	Loss
TK_Src_SrcA_SRC_Y	P35222	CTNNB1	P12931	SRC	Y333	L336P	336	Missense	distal	3	no	22.219	22.317	PhosphoSitePlus;EPSD	TCGA;COSMIC	20.673	Up-regulation
TK_Src_SrcA_SRC_Y	P35222	CTNNB1	P12931	SRC	Y716	R717H	717	Missense	proximal	1	no	21.309	21.236	EPSD	TCGA;COSMIC	20.673	Down-regulation
TK_Src_SrcA_SRC_Y	P35222	CTNNB1	P12931	SRC	Y716	P714R	714	Missense	proximal	-2	no	21.309	19.778	EPSD	TCGA;COSMIC	20.673	Loss
TK_Src_SrcA_SRC_Y	P35222	CTNNB1	P12931	SRC	Y716	P714L	714	Missense	proximal	-2	no	21.309	19.779	EPSD	TCGA;COSMIC	20.673	Loss
TK_Src_SrcA_SRC_Y	P35222	CTNNB1	P12931	SRC	Y724	R717H	717	Missense	distal	-7	no	20.894	20.599	EPSD	TCGA;COSMIC	20.673	Loss
TK_Src_SrcA_SRC_Y	P09327	VIL1	P12931	SRC	Y461	V464I	464	Missense	distal	3	no	21.130	21.070	EPSD	TCGA;COSMIC	20.673	Down-regulation
TK_Src_SrcA_SRC_Y	P01889	HLA-B	P12931	SRC	Y344	G339V	339	Missense	distal	-5	no	21.507	21.478	PhosphoSitePlus	TCGA;ICGC;COSMIC	20.673	Down-regulation
TK_Src_SrcA_SRC_Y	P01889	HLA-B	P12931	SRC	Y344	G339A	339	Missense	distal	-5	no	21.507	21.477	PhosphoSitePlus	TCGA;ICGC;COSMIC	20.673	Down-regulation
TK_Src_SrcA_SRC_Y	P01889	HLA-B	P12931	SRC	Y344	G338S	338	Missense	distal	-6	no	21.507	21.650	PhosphoSitePlus	TCGA;ICGC;COSMIC	20.673	Up-regulation
TK_Src_SrcA_SRC_Y	P01889	HLA-B	P12931	SRC	Y344	A348V	348	Missense	distal	4	no	21.507	21.480	PhosphoSitePlus	TCGA;ICGC;COSMIC;GDSC	20.673	Down-regulation
TK_Src_SrcA_SRC_Y	Q13769	THOC5	P12931	SRC	Y37	Y37C	37	Missense	central	0	yes	22.081	0.000	EPSD	TCGA;ICGC;COSMIC	20.673	Loss
TK_Src_SrcA_SRC_Y	Q13769	THOC5	P12931	SRC	Y37	A41T	41	Missense	distal	4	no	22.081	22.077	EPSD	TCGA;ICGC;COSMIC	20.673	Down-regulation
TK_Src_SrcA_SRC_Y	Q9Y3Q4	HCN4	P12931	SRC	Y13	R11Q	11	Missense	proximal	-2	no	20.018	20.763	EPSD	TCGA;ICGC;COSMIC;CCLE	20.673	Gain
TK_Src_SrcA_SRC_Y	Q9Y3Q4	HCN4	P12931	SRC	Y506	A513T	513	Missense	distal	7	no	22.963	22.943	EPSD	TCGA;ICGC;COSMIC	20.673	Down-regulation
TK_Src_SrcA_SRC_Y	Q9Y3Q4	HCN4	P12931	SRC	Y506	F509L	509	Missense	distal	3	no	22.963	22.722	EPSD	TCGA;ICGC	20.673	Down-regulation
TK_Src_SrcA_SRC_Y	Q9Y3Q4	HCN4	P12931	SRC	Y531	R525H	525	Missense	distal	-6	no	21.210	21.177	PhosphoSitePlus	TCGA;ICGC;COSMIC	20.673	Down-regulation
TK_Src_SrcA_SRC_Y	Q9Y3Q4	HCN4	P12931	SRC	Y531	M538L	538	Missense	distal	7	no	21.210	21.157	PhosphoSitePlus	TCGA;ICGC;COSMIC	20.673	Down-regulation
TK_Src_SrcA_SRC_Y	Q9Y3Q4	HCN4	P12931	SRC	Y531	V534E	534	Missense	distal	3	no	21.210	20.555	PhosphoSitePlus	TCGA;ICGC;COSMIC	20.673	Loss
TK_Src_SrcA_SRC_Y	Q9Y3Q4	HCN4	P12931	SRC	Y531	M538I	538	Missense	distal	7	no	21.210	21.184	PhosphoSitePlus	TCGA;ICGC;COSMIC	20.673	Down-regulation
TK_Src_SrcA_SRC_Y	Q9Y3Q4	HCN4	P12931	SRC	Y531	K532T	532	Missense	proximal	1	no	21.210	21.852	PhosphoSitePlus	TCGA;ICGC	20.673	Up-regulation
TK_Src_SrcA_SRC_Y	Q9Y3Q4	HCN4	P12931	SRC	Y531	Y537C	537	Missense	distal	6	no	21.210	21.251	PhosphoSitePlus	TCGA;ICGC	20.673	Up-regulation
TK_Src_SrcA_SRC_Y	Q9Y3Q4	HCN4	P12931	SRC	Y537	M538L	538	Missense	proximal	1	no	21.034	20.895	EPSD	TCGA;ICGC;COSMIC	20.673	Down-regulation
TK_Src_SrcA_SRC_Y	Q9Y3Q4	HCN4	P12931	SRC	Y537	V534E	534	Missense	distal	-3	no	21.034	22.913	EPSD	TCGA;ICGC;COSMIC	20.673	Up-regulation
TK_Src_SrcA_SRC_Y	Q9Y3Q4	HCN4	P12931	SRC	Y537	M538I	538	Missense	proximal	1	no	21.034	20.997	EPSD	TCGA;ICGC;COSMIC	20.673	Down-regulation
TK_Src_SrcA_SRC_Y	Q9Y3Q4	HCN4	P12931	SRC	Y537	K532T	532	Missense	distal	-5	no	21.034	21.117	EPSD	TCGA;ICGC	20.673	Up-regulation
TK_Src_SrcA_SRC_Y	Q9Y3Q4	HCN4	P12931	SRC	Y537	Y537C	537	Missense	central	0	yes	21.034	0.000	EPSD	TCGA;ICGC	20.673	Loss
TK_Src_SrcA_SRC_Y	P04083	ANXA1	P12931	SRC	Y21	S27L	27	Missense	distal	6	no	22.100	22.132	PhosphoSitePlus	TCGA;ICGC;COSMIC	20.673	Up-regulation
TK_Src_SrcA_SRC_Y	P04083	ANXA1	P12931	SRC	Y21	E17K	17	Missense	distal	-4	no	22.100	20.930	PhosphoSitePlus	TCGA;ICGC;COSMIC	20.673	Down-regulation
TK_Src_SrcA_SRC_Y	P49279	SLC11A1	P12931	SRC	Y15	G16C	16	Missense	proximal	1	no	23.138	20.841	PhosphoSitePlus	TCGA	20.673	Down-regulation
TK_Src_SrcA_SRC_Y	P48048	KCNJ1	P12931	SRC	Y337	T332K	332	Missense	distal	-5	no	21.579	21.496	PhosphoSitePlus	TCGA;COSMIC	20.673	Down-regulation
TK_Src_SrcA_SRC_Y	P48048	KCNJ1	P12931	SRC	Y337	G335R	335	Missense	proximal	-2	no	21.579	20.221	PhosphoSitePlus	TCGA;COSMIC	20.673	Loss
TK_Src_SrcA_SRC_Y	P48048	KCNJ1	P12931	SRC	Y337	F341L	341	Missense	distal	4	no	21.579	21.597	PhosphoSitePlus	TCGA;COSMIC	20.673	Up-regulation
TK_Src_SrcA_SRC_Y	P31431	SDC4	P12931	SRC	Y180	G183C	183	Missense	distal	3	no	21.173	20.100	PhosphoSitePlus	TCGA;COSMIC	20.673	Loss
TK_Src_SrcA_SRC_Y	P31431	SDC4	P12931	SRC	Y180	S179G	179	Missense	proximal	-1	no	21.173	20.630	PhosphoSitePlus	TCGA;COSMIC	20.673	Loss
TK_Src_SrcA_SRC_Y	P31431	SDC4	P12931	SRC	Y180	K184N	184	Missense	distal	4	no	21.173	21.217	PhosphoSitePlus	TCGA;COSMIC	20.673	Up-regulation
TK_Src_SrcA_SRC_Y	P31431	SDC4	P12931	SRC	Y180	D181Y	181	Missense	proximal	1	no	21.173	20.775	PhosphoSitePlus	TCGA;COSMIC	20.673	Down-regulation
TK_Src_SrcA_SRC_Y	P01111	NRAS	P12931	SRC	Y32	P34L	34	Missense	proximal	2	no	20.815	20.359	PhosphoSitePlus	TCGA;ICGC;COSMIC	20.673	Loss
TK_Src_SrcA_SRC_Y	P01111	NRAS	P12931	SRC	Y64	Q61K	61	Missense	distal	-3	no	23.002	22.171	EPSD	TCGA;ICGC;COSMIC;GDSC;CCLE	20.673	Down-regulation
TK_Src_SrcA_SRC_Y	P01111	NRAS	P12931	SRC	Y64	Q61R	61	Missense	distal	-3	no	23.002	22.386	EPSD	TCGA;ICGC;COSMIC;GDSC;CCLE	20.673	Down-regulation
TK_Src_SrcA_SRC_Y	P01111	NRAS	P12931	SRC	Y64	D57A	57	Missense	distal	-7	no	23.002	22.629	EPSD	TCGA;ICGC;COSMIC	20.673	Down-regulation
TK_Src_SrcA_SRC_Y	P01111	NRAS	P12931	SRC	Y64	Q61L	61	Missense	distal	-3	no	23.002	21.191	EPSD	TCGA;ICGC;COSMIC;GDSC;CCLE	20.673	Down-regulation
TK_Src_SrcA_SRC_Y	P01111	NRAS	P12931	SRC	Y64	Q61H	61	Missense	distal	-3	no	23.002	22.351	EPSD	TCGA;ICGC;COSMIC;GDSC;CCLE	20.673	Down-regulation
TK_Src_SrcA_SRC_Y	P01111	NRAS	P12931	SRC	Y64	E62K	62	Missense	proximal	-2	no	23.002	21.643	EPSD	TCGA;ICGC;COSMIC	20.673	Down-regulation
TK_Src_SrcA_SRC_Y	P01111	NRAS	P12931	SRC	Y64	A66V	66	Missense	proximal	2	no	23.002	23.213	EPSD	TCGA;COSMIC	20.673	Up-regulation
TK_Src_SrcA_SRC_Y	P01111	NRAS	P12931	SRC	Y157	R164H	164	Missense	distal	7	no	21.101	21.087	EPSD	TCGA;ICGC	20.673	Down-regulation
TK_Src_SrcA_SRC_Y	P01111	NRAS	P12931	SRC	Y157	R164C	164	Missense	distal	7	no	21.101	21.173	EPSD	TCGA;ICGC;COSMIC	20.673	Up-regulation
TK_Src_SrcA_SRC_Y	Q9NZQ3	NCKIPSD	P12931	SRC	Y161	D157H	157	Missense	distal	-4	no	22.909	21.748	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	20.673	Down-regulation
TK_Src_SrcA_SRC_Y	Q9NZQ3	NCKIPSD	P12931	SRC	Y161	L154V	154	Missense	distal	-7	no	22.909	22.872	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	20.673	Down-regulation
TK_Src_SrcA_SRC_Y	Q9NZQ3	NCKIPSD	P12931	SRC	Y227	D224V	224	Missense	distal	-3	no	21.295	19.370	PhosphoSitePlus;EPSD	TCGA;COSMIC	20.673	Loss
TK_Src_SrcA_SRC_Y	Q9NZQ3	NCKIPSD	P12931	SRC	Y227	D224G	224	Missense	distal	-3	no	21.295	20.646	PhosphoSitePlus;EPSD	TCGA;COSMIC	20.673	Loss
TK_Src_SrcA_SRC_Y	Q9NZQ3	NCKIPSD	P12931	SRC	Y227	S229N	229	Missense	proximal	2	no	21.295	21.047	PhosphoSitePlus;EPSD	TCGA;COSMIC	20.673	Down-regulation
TK_Src_SrcA_SRC_Y	Q68CZ2	TNS3	P12931	SRC	Y549	R553Q	553	Missense	distal	4	no	21.183	21.205	EPSD	TCGA;ICGC;COSMIC	20.673	Up-regulation
TK_Src_SrcA_SRC_Y	P46937	YAP1	P12931	SRC	Y391	E396D	396	Missense	distal	5	no	21.123	20.915	EPSD	TCGA;ICGC;COSMIC	20.673	Down-regulation
TK_Src_SrcA_SRC_Y	Q9UKT4	FBXO5	P12931	SRC	Y318	F321C	321	Missense	distal	3	no	21.250	19.533	EPSD	TCGA;COSMIC	20.673	Loss
TK_Src_SrcA_SRC_Y	P08238	HSP90AB1	P12931	SRC	Y192	E195D	195	Missense	distal	3	no	20.852	20.757	EPSD	TCGA;ICGC;COSMIC	20.673	Down-regulation
TK_Src_SrcA_SRC_Y	P08238	HSP90AB1	P12931	SRC	Y192	K186E	186	Missense	distal	-6	no	20.852	20.864	EPSD	TCGA;ICGC;COSMIC	20.673	Up-regulation
TK_Src_SrcA_SRC_Y	P08238	HSP90AB1	P12931	SRC	Y192	R197W	197	Missense	distal	5	no	20.852	21.444	EPSD	TCGA;ICGC;COSMIC	20.673	Up-regulation
TK_Src_SrcA_SRC_Y	P08238	HSP90AB1	P12931	SRC	Y301	E303K	303	Missense	proximal	2	no	23.893	22.724	PhosphoSitePlus	TCGA;ICGC;COSMIC	20.673	Down-regulation
TK_Src_SrcA_SRC_Y	P08238	HSP90AB1	P12931	SRC	Y301	F304L	304	Missense	distal	3	no	23.893	23.653	PhosphoSitePlus	TCGA;ICGC;COSMIC	20.673	Down-regulation
TK_Src_SrcA_SRC_Y	P08238	HSP90AB1	P12931	SRC	Y305	D311Y	311	Missense	distal	6	no	22.401	22.456	EPSD	TCGA;ICGC;COSMIC	20.673	Up-regulation
TK_Src_SrcA_SRC_Y	P08238	HSP90AB1	P12931	SRC	Y305	E303K	303	Missense	proximal	-2	no	22.401	21.042	EPSD	TCGA;ICGC;COSMIC	20.673	Down-regulation
TK_Src_SrcA_SRC_Y	P08238	HSP90AB1	P12931	SRC	Y305	F304L	304	Missense	proximal	-1	no	22.401	23.260	EPSD	TCGA;ICGC;COSMIC	20.673	Up-regulation
TK_Src_SrcA_SRC_Y	P08238	HSP90AB1	P12931	SRC	Y430	K427N	427	Missense	distal	-3	no	21.849	23.097	EPSD	TCGA;ICGC;COSMIC	20.673	Up-regulation
TK_Src_SrcA_SRC_Y	Q9NV92	NDFIP2	P12931	SRC	Y151	P149S	149	Missense	proximal	-2	no	21.718	20.932	EPSD	TCGA;ICGC;COSMIC	20.673	Down-regulation
TK_Src_SrcA_SRC_Y	Q9NV92	NDFIP2	P12931	SRC	Y186	L183V	183	Missense	distal	-3	no	20.224	21.036	EPSD	TCGA;ICGC;COSMIC	20.673	Gain
TK_Src_SrcA_SRC_Y	Q969T9	WBP2	P12931	SRC	Y232	A228T	228	Missense	distal	-4	no	20.903	21.178	EPSD	TCGA;COSMIC	20.673	Up-regulation
TK_Src_SrcA_SRC_Y	P10398	ARAF	P12931	SRC	Y42	D43N	43	Missense	proximal	1	no	22.899	21.508	EPSD	TCGA;ICGC;COSMIC	20.673	Down-regulation
TK_Src_SrcA_SRC_Y	P10398	ARAF	P12931	SRC	Y42	V41I	41	Missense	proximal	-1	no	22.899	22.525	EPSD	TCGA;ICGC;COSMIC	20.673	Down-regulation
TK_Src_SrcA_SRC_Y	P10398	ARAF	P12931	SRC	Y155	F154L	154	Missense	proximal	-1	no	20.789	21.648	EPSD	TCGA;ICGC;COSMIC	20.673	Up-regulation
TK_Src_SrcA_SRC_Y	P10398	ARAF	P12931	SRC	Y155	R151H	151	Missense	distal	-4	no	20.789	20.305	EPSD	TCGA;ICGC;COSMIC	20.673	Loss
TK_Src_SrcA_SRC_Y	P10398	ARAF	P12931	SRC	Y301	Y296C	296	Missense	distal	-5	no	22.006	21.742	EPSD;PhosphoSitePlus	TCGA;ICGC	20.673	Down-regulation
TK_Src_SrcA_SRC_Y	P10398	ARAF	P12931	SRC	Y302	Y296C	296	Missense	distal	-6	no	23.384	22.851	PhosphoSitePlus;EPSD	TCGA;ICGC	20.673	Down-regulation
TK_Src_SrcA_SRC_Y	P98175	RBM10	P12931	SRC	Y16	R15C	15	Missense	proximal	-1	no	22.309	23.730	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	20.673	Up-regulation
TK_Src_SrcA_SRC_Y	P98175	RBM10	P12931	SRC	Y36	R30H	30	Missense	distal	-6	no	20.980	20.948	EPSD	TCGA;ICGC;COSMIC	20.673	Down-regulation
TK_Src_SrcA_SRC_Y	P98175	RBM10	P12931	SRC	Y48	R46H	46	Missense	proximal	-2	no	20.514	21.380	EPSD	TCGA;ICGC;COSMIC	20.673	Gain
TK_Src_SrcA_SRC_Y	P98175	RBM10	P12931	SRC	Y57	E62D	62	Missense	distal	5	no	21.216	21.009	EPSD	TCGA;ICGC;COSMIC	20.673	Down-regulation
TK_Src_SrcA_SRC_Y	P98175	RBM10	P12931	SRC	Y57	K54N	54	Missense	distal	-3	no	21.216	22.465	EPSD	TCGA;ICGC;COSMIC	20.673	Up-regulation
TK_Src_SrcA_SRC_Y	P98175	RBM10	P12931	SRC	Y57	H55Y	55	Missense	proximal	-2	no	21.216	20.548	EPSD	TCGA;ICGC;COSMIC	20.673	Loss
TK_Src_SrcA_SRC_Y	P98175	RBM10	P12931	SRC	Y57	G53D	53	Missense	distal	-4	no	21.216	21.875	EPSD	TCGA;ICGC;COSMIC	20.673	Up-regulation
TK_Src_SrcA_SRC_Y	P98175	RBM10	P12931	SRC	Y70	A66V	66	Missense	distal	-4	no	22.513	22.379	EPSD	TCGA;ICGC	20.673	Down-regulation
TK_Src_SrcA_SRC_Y	P98175	RBM10	P12931	SRC	Y70	E71K	71	Missense	proximal	1	no	22.513	20.118	EPSD	TCGA;ICGC;COSMIC	20.673	Loss
TK_Src_SrcA_SRC_Y	P98175	RBM10	P12931	SRC	Y107	E110D	110	Missense	distal	3	no	21.824	21.729	EPSD	TCGA;ICGC;COSMIC	20.673	Down-regulation
TK_Src_SrcA_SRC_Y	P98175	RBM10	P12931	SRC	Y107	R108Q	108	Missense	proximal	1	no	21.824	22.817	EPSD	TCGA;ICGC;COSMIC	20.673	Up-regulation
TK_Src_SrcA_SRC_Y	P98175	RBM10	P12931	SRC	Y561	D568N	568	Missense	distal	7	no	21.534	21.532	EPSD	TCGA;COSMIC	20.673	Down-regulation
TK_Src_SrcA_SRC_Y	P98175	RBM10	P12931	SRC	Y561	Y564F	564	Missense	distal	3	no	21.534	22.175	EPSD	TCGA;COSMIC	20.673	Up-regulation
TK_Src_SrcA_SRC_Y	P98175	RBM10	P12931	SRC	Y561	T556S	556	Missense	distal	-5	no	21.534	21.842	EPSD	TCGA;COSMIC	20.673	Up-regulation
TK_Src_SrcA_SRC_Y	P98175	RBM10	P12931	SRC	Y561	P565T	565	Missense	distal	4	no	21.534	21.549	EPSD	TCGA;COSMIC	20.673	Up-regulation
TK_Src_SrcA_SRC_Y	P98175	RBM10	P12931	SRC	Y825	E820K	820	Missense	distal	-5	no	20.859	20.283	EPSD	TCGA;COSMIC	20.673	Loss
TK_Src_SrcA_SRC_Y	P51636	CAV2	P12931	SRC	Y27	A34S	34	Missense	distal	7	no	23.474	23.485	EPSD	TCGA;ICGC;COSMIC	20.673	Up-regulation
TK_Src_SrcA_SRC_Y	P51636	CAV2	P12931	SRC	Y27	A34T	34	Missense	distal	7	no	23.474	23.455	EPSD	TCGA;ICGC;COSMIC	20.673	Down-regulation
TK_Src_SrcA_SRC_Y	Q15642	TRIP10	P12931	SRC	Y190	E189K	189	Missense	proximal	-1	no	22.464	20.555	EPSD	TCGA	20.673	Loss
TK_Src_SrcA_SRC_Y	Q15642	TRIP10	P12931	SRC	Y190	A192T	192	Missense	proximal	2	no	22.464	22.557	EPSD	TCGA;ICGC;COSMIC	20.673	Up-regulation
TK_Src_SrcA_SRC_Y	Q15642	TRIP10	P12931	SRC	Y190	A191T	191	Missense	proximal	1	no	22.464	22.009	EPSD	TCGA;ICGC;COSMIC	20.673	Down-regulation
TK_Src_SrcA_SRC_Y	P60953	CDC42	P12931	SRC	Y64	R66K	66	Missense	proximal	2	no	21.957	21.445	PhosphoSitePlus	TCGA;COSMIC	20.673	Down-regulation
TK_Src_SrcA_SRC_Y	P60953	CDC42	P12931	SRC	Y64	D65V	65	Missense	proximal	1	no	21.957	20.681	PhosphoSitePlus	TCGA;COSMIC	20.673	Down-regulation
TK_Src_SrcA_SRC_Y	P60953	CDC42	P12931	SRC	Y64	D63V	63	Missense	proximal	-1	no	21.957	23.390	PhosphoSitePlus	TCGA;COSMIC	20.673	Up-regulation
TK_Src_SrcA_SRC_Y	P60953	CDC42	P12931	SRC	Y64	E62D	62	Missense	proximal	-2	no	21.957	21.669	PhosphoSitePlus	TCGA;COSMIC	20.673	Down-regulation
TK_Src_SrcA_SRC_Y	P60953	CDC42	P12931	SRC	Y64	D57Y	57	Missense	distal	-7	no	21.957	21.506	PhosphoSitePlus	TCGA;COSMIC	20.673	Down-regulation
TK_Src_SrcA_SRC_Y	P52566	ARHGDIB	P12931	SRC	Y153	Y146C	146	Missense	distal	-7	no	23.618	23.125	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	20.673	Down-regulation
TK_Src_SrcA_SRC_Y	P52566	ARHGDIB	P12931	SRC	Y153	E154D	154	Missense	proximal	1	no	23.618	23.012	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	20.673	Down-regulation
TK_Src_SrcA_SRC_Y	P52566	ARHGDIB	P12931	SRC	Y153	T157A	157	Missense	distal	4	no	23.618	23.622	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	20.673	Up-regulation
TK_Src_SrcA_SRC_Y	P52565	ARHGDIA	P12931	SRC	Y156	E154K	154	Missense	proximal	-2	no	23.928	22.568	EPSD;PhosphoSitePlus	TCGA;COSMIC	20.673	Down-regulation
TK_Src_SrcA_SRC_Y	P52565	ARHGDIA	P12931	SRC	Y156	R152W	152	Missense	distal	-4	no	23.928	22.555	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	20.673	Down-regulation
TK_Src_SrcA_SRC_Y	P49789	FHIT	P12931	SRC	Y114	E115K	115	Missense	proximal	1	no	24.910	22.515	PhosphoSitePlus	TCGA;ICGC;COSMIC	20.673	Down-regulation
TK_Src_SrcA_SRC_Y	P49789	FHIT	P12931	SRC	Y114	D111H	111	Missense	distal	-3	no	24.910	23.333	PhosphoSitePlus	TCGA;ICGC;COSMIC	20.673	Down-regulation
TK_Src_SrcA_SRC_Y	P49789	FHIT	P12931	SRC	Y114	H108R	108	Missense	distal	-6	no	24.910	24.942	PhosphoSitePlus	TCGA;ICGC;COSMIC	20.673	Up-regulation
TK_Src_SrcA_SRC_Y	Q15417	CNN3	P12931	SRC	Y10	K17N	17	Missense	distal	7	no	20.934	20.889	PhosphoSitePlus	TCGA;ICGC;COSMIC;CCLE	20.673	Down-regulation
TK_Src_SrcA_SRC_Y	Q16595	FXN	P12931	SRC	Y143	T149M	149	Missense	distal	6	no	21.346	21.397	EPSD	TCGA;ICGC;COSMIC	20.673	Up-regulation
TK_Src_SrcA_SRC_Y	Q16595	FXN	P12931	SRC	Y143	I145T	145	Missense	proximal	2	no	21.346	22.424	EPSD	TCGA;ICGC;COSMIC	20.673	Up-regulation
TK_Src_SrcA_SRC_Y	Q05655	PRKCD	P12931	SRC	Y64	R67C	67	Missense	distal	3	no	21.321	21.533	EPSD	TCGA;ICGC;COSMIC	20.673	Up-regulation
TK_Src_SrcA_SRC_Y	Q05655	PRKCD	P12931	SRC	Y64	S57L	57	Missense	distal	-7	no	21.321	21.085	EPSD	TCGA;ICGC;COSMIC;GDSC;CCLE	20.673	Down-regulation
TK_Src_SrcA_SRC_Y	Q05655	PRKCD	P12931	SRC	Y514	C509R	509	Missense	distal	-5	no	21.007	21.727	EPSD	TCGA;ICGC;COSMIC	20.673	Up-regulation
TK_Src_SrcA_SRC_Y	Q05655	PRKCD	P12931	SRC	Y514	T511N	511	Missense	distal	-3	no	21.007	21.677	EPSD	TCGA;ICGC;COSMIC	20.673	Up-regulation
TK_Src_SrcA_SRC_Y	Q05655	PRKCD	P12931	SRC	Y514	A516S	516	Missense	proximal	2	no	21.007	21.359	EPSD	TCGA;ICGC;COSMIC	20.673	Up-regulation
TK_Src_SrcA_SRC_Y	Q05655	PRKCD	P12931	SRC	Y514	L520I	520	Missense	distal	6	no	21.007	20.995	EPSD	TCGA;ICGC;COSMIC	20.673	Down-regulation
TK_Src_SrcA_SRC_Y	Q05655	PRKCD	P12931	SRC	Y567	P568S	568	Missense	proximal	1	no	21.050	23.196	EPSD	TCGA;ICGC;COSMIC	20.673	Up-regulation
TK_Src_SrcA_SRC_Y	P42229	STAT5A	P12931	SRC	Y683	Y683S	683	Missense	central	0	yes	20.697	0.000	EPSD	TCGA;COSMIC	20.673	Loss
TK_Src_SrcA_SRC_Y	P46527	CDKN1B	P12931	SRC	Y74	G72D	72	Missense	proximal	-2	no	21.499	21.789	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	20.673	Up-regulation
TK_Src_SrcA_SRC_Y	P46527	CDKN1B	P12931	SRC	Y74	K81R	81	Missense	distal	7	no	21.499	21.525	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	20.673	Up-regulation
TK_Src_SrcA_SRC_Y	P46527	CDKN1B	P12931	SRC	Y88	K81R	81	Missense	distal	-7	no	21.012	21.345	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	20.673	Up-regulation
TK_Src_SrcA_SRC_Y	P46527	CDKN1B	P12931	SRC	Y89	K96Q	96	Missense	distal	7	no	22.542	22.525	PhosphoSitePlus;EPSD	TCGA;ICGC;COSMIC	20.673	Down-regulation
TK_Src_SrcA_SRC_Y	Q96AC1	FERMT2	P12931	SRC	Y179	G176E	176	Missense	distal	-3	no	23.819	24.423	EPSD	TCGA;ICGC;COSMIC	20.673	Up-regulation
TK_Src_SrcA_SRC_Y	Q96AE4	FUBP1	P12931	SRC	Y590	M593T	593	Missense	distal	3	no	21.333	21.174	EPSD	TCGA;ICGC;COSMIC	20.673	Down-regulation
TK_Src_SrcA_SRC_Y	Q96AE4	FUBP1	P12931	SRC	Y611	E617Q	617	Missense	distal	6	no	21.502	21.484	EPSD	TCGA;ICGC;COSMIC	20.673	Down-regulation
TK_Src_SrcA_SRC_Y	Q96AE4	FUBP1	P12931	SRC	Y611	Y611C	611	Missense	central	0	yes	21.502	0.000	EPSD	TCGA;ICGC;COSMIC	20.673	Loss
TK_Src_SrcA_SRC_Y	Q96AE4	FUBP1	P12931	SRC	Y611	P604H	604	Missense	distal	-7	no	21.502	21.576	EPSD	TCGA;ICGC;COSMIC	20.673	Up-regulation
TK_Src_SrcA_SRC_Y	P55211	CASP9	P12931	SRC	Y251	G255R	255	Missense	distal	4	no	22.764	22.762	PhosphoSitePlus	TCGA;ICGC;COSMIC	20.673	Down-regulation
TK_Src_SrcA_SRC_Y	P55211	CASP9	P12931	SRC	Y251	F246L	246	Missense	distal	-5	no	22.764	22.828	PhosphoSitePlus	TCGA;ICGC;COSMIC	20.673	Up-regulation
TK_Src_SrcA_SRC_Y	O95297	MPZL1	P12931	SRC	Y263	A264V	264	Missense	proximal	1	no	21.164	20.580	PhosphoSitePlus;EPSD	TCGA	20.673	Loss
TK_Src_SrcA_SRC_Y	O95297	MPZL1	P12931	SRC	Y263	S258L	258	Missense	distal	-5	no	21.164	20.906	PhosphoSitePlus;EPSD	TCGA;ICGC;COSMIC	20.673	Down-regulation
TK_Src_SrcA_SRC_Y	O95297	MPZL1	P12931	SRC	Y263	R267Q	267	Missense	distal	4	no	21.164	21.186	PhosphoSitePlus;EPSD	TCGA;ICGC;COSMIC	20.673	Up-regulation
TK_Src_SrcA_SRC_Y	O95297	MPZL1	P12931	SRC	Y263	Y263C	263	Missense	central	0	yes	21.164	0.000	PhosphoSitePlus;EPSD	TCGA;ICGC;COSMIC	20.673	Loss
TK_Src_SrcA_SRC_Y	O95297	MPZL1	P12931	SRC	Y263	K268N	268	Missense	distal	5	no	21.164	21.082	PhosphoSitePlus;EPSD	TCGA;ICGC	20.673	Down-regulation
TK_Src_SrcA_SRC_Y	Q96KB5	PBK	P12931	SRC	Y74	R75Q	75	Missense	proximal	1	no	20.120	21.112	PhosphoSitePlus;EPSD	TCGA;ICGC;COSMIC	20.673	Gain
TK_Src_SrcA_SRC_Y	Q9NPY3	CD93	P12931	SRC	Y628	A625T	625	Missense	distal	-3	no	21.340	21.534	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	20.673	Up-regulation
TK_Src_SrcA_SRC_Y	Q9NPY3	CD93	P12931	SRC	Y628	S629F	629	Missense	proximal	1	no	21.340	19.462	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	20.673	Loss
TK_Src_SrcA_SRC_Y	Q9NPY3	CD93	P12931	SRC	Y628	P632L	632	Missense	distal	4	no	21.340	21.368	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	20.673	Up-regulation
TK_Src_SrcA_SRC_Y	P05106	ITGB3	P12931	SRC	Y773	T767K	767	Missense	distal	-6	no	20.548	20.675	PhosphoSitePlus;EPSD	TCGA;ICGC;COSMIC	20.673	Gain
TK_Src_SrcA_SRC_Y	P05106	ITGB3	P12931	SRC	Y773	S778C	778	Missense	distal	5	no	20.548	21.007	PhosphoSitePlus;EPSD	TCGA;ICGC;COSMIC	20.673	Gain
TK_Src_SrcA_SRC_Y	Q9NPF5	DMAP1	P12931	SRC	Y58	G52D	52	Missense	distal	-6	no	21.313	21.620	EPSD	TCGA;ICGC;COSMIC	20.673	Up-regulation
TK_Src_SrcA_SRC_Y	Q9NPF5	DMAP1	P12931	SRC	Y58	E51D	51	Missense	distal	-7	no	21.313	21.285	EPSD	TCGA;ICGC;COSMIC	20.673	Down-regulation
TK_Src_SrcA_SRC_Y	Q14258	TRIM25	P12931	SRC	Y456	K458N	458	Missense	proximal	2	no	20.207	21.302	EPSD	TCGA;ICGC;COSMIC	20.673	Gain
TK_Src_SrcA_SRC_Y	O15056	SYNJ2	P12931	SRC	Y1136	T1141S	1141	Missense	distal	5	no	20.704	20.534	EPSD	TCGA;ICGC;COSMIC	20.673	Loss
TK_Src_SrcA_SRC_Y	O15056	SYNJ2	P12931	SRC	Y1136	S1130F	1130	Missense	distal	-6	no	20.704	20.568	EPSD	TCGA;ICGC;COSMIC	20.673	Loss
TK_Src_SrcA_SRC_Y	O15056	SYNJ2	P12931	SRC	Y1136	Q1135E	1135	Missense	proximal	-1	no	20.704	21.110	EPSD	TCGA;ICGC;COSMIC	20.673	Up-regulation
TK_Src_SrcA_SRC_Y	O15056	SYNJ2	P12931	SRC	Y1136	T1141M	1141	Missense	distal	5	no	20.704	20.926	EPSD	TCGA;ICGC;COSMIC;GDSC;CCLE	20.673	Up-regulation
TK_Src_SrcA_SRC_Y	O15056	SYNJ2	P12931	SRC	Y1411	L1408V	1408	Missense	distal	-3	no	20.502	21.314	EPSD	TCGA;ICGC;COSMIC	20.673	Gain
TK_Src_SrcA_SRC_Y	Q99704	DOK1	P12931	SRC	Y146	E139D	139	Missense	distal	-7	no	21.479	21.451	EPSD	TCGA;ICGC;COSMIC	20.673	Down-regulation
TK_Src_SrcA_SRC_Y	Q99704	DOK1	P12931	SRC	Y315	S310F	310	Missense	distal	-5	no	21.446	21.123	EPSD	TCGA;COSMIC	20.673	Down-regulation
TK_Src_SrcA_SRC_Y	Q99704	DOK1	P12931	SRC	Y315	D317N	317	Missense	proximal	2	no	21.446	21.659	EPSD	TCGA;COSMIC	20.673	Up-regulation
TK_Src_SrcA_SRC_Y	Q99704	DOK1	P12931	SRC	Y315	P318S	318	Missense	distal	3	no	21.446	20.708	EPSD	TCGA;ICGC	20.673	Down-regulation
TK_Src_SrcA_SRC_Y	Q99704	DOK1	P12931	SRC	Y337	E342G	342	Missense	distal	5	no	20.863	21.020	EPSD	TCGA;COSMIC	20.673	Up-regulation
TK_Src_SrcA_SRC_Y	Q99704	DOK1	P12931	SRC	Y337	R332Q	332	Missense	distal	-5	no	20.863	20.704	EPSD	TCGA;ICGC;COSMIC	20.673	Down-regulation
TK_Src_SrcA_SRC_Y	Q99704	DOK1	P12931	SRC	Y337	P335L	335	Missense	proximal	-2	no	20.863	19.332	EPSD	TCGA	20.673	Loss
TK_Src_SrcA_SRC_Y	Q99704	DOK1	P12931	SRC	Y362	P365H	365	Missense	distal	3	no	25.224	24.627	PhosphoSitePlus	TCGA;COSMIC	20.673	Down-regulation
TK_Src_SrcA_SRC_Y	Q99704	DOK1	P12931	SRC	Y377	P370Q	370	Missense	distal	-7	no	22.425	22.569	EPSD	TCGA;COSMIC	20.673	Up-regulation
TK_Src_SrcA_SRC_Y	Q99704	DOK1	P12931	SRC	Y398	P404L	404	Missense	distal	6	no	22.688	22.704	EPSD	TCGA;COSMIC	20.673	Up-regulation
TK_Src_SrcA_SRC_Y	Q99704	DOK1	P12931	SRC	Y409	P404L	404	Missense	distal	-5	no	21.550	21.393	EPSD	TCGA;COSMIC	20.673	Down-regulation
TK_Src_SrcA_SRC_Y	Q9UBS0	RPS6KB2	P12931	SRC	Y45	P41L	41	Missense	distal	-4	no	21.312	20.677	PhosphoSitePlus	TCGA;ICGC;COSMIC	20.673	Down-regulation
TK_Src_SrcA_SRC_Y	P51692	STAT5B	P12931	SRC	Y679	S680F	680	Missense	proximal	1	no	23.363	21.486	EPSD	TCGA;ICGC;COSMIC	20.673	Down-regulation
TK_Src_SrcA_SRC_Y	P63010	AP2B1	P12931	SRC	Y136	A142T	142	Missense	distal	6	no	20.851	20.837	EPSD	TCGA;ICGC	20.673	Down-regulation
TK_Src_SrcA_SRC_Y	P63010	AP2B1	P12931	SRC	Y136	R138Q	138	Missense	proximal	2	no	20.851	21.200	EPSD	TCGA;ICGC;COSMIC	20.673	Up-regulation
TK_Src_SrcA_SRC_Y	P63010	AP2B1	P12931	SRC	Y136	P135S	135	Missense	proximal	-1	no	20.851	20.499	EPSD	TCGA;ICGC;COSMIC	20.673	Loss
TK_Src_SrcA_SRC_Y	P63010	AP2B1	P12931	SRC	Y276	D273N	273	Missense	distal	-3	no	20.937	20.429	EPSD	TCGA;ICGC;COSMIC	20.673	Loss
TK_Src_SrcA_SRC_Y	P63010	AP2B1	P12931	SRC	Y277	D273N	273	Missense	distal	-4	no	21.866	21.334	EPSD	TCGA;ICGC;COSMIC	20.673	Down-regulation
TK_Src_SrcA_SRC_Y	P63010	AP2B1	P12931	SRC	Y333	V326L	326	Missense	distal	-7	no	21.042	21.078	EPSD	TCGA;ICGC;COSMIC	20.673	Up-regulation
TK_Src_SrcA_SRC_Y	P63000	RAC1	P12931	SRC	Y64	D63N	63	Missense	proximal	-1	no	21.521	20.571	PhosphoSitePlus	TCGA;ICGC;COSMIC;GDSC;CCLE	20.673	Loss
TK_Src_SrcA_SRC_Y	P63000	RAC1	P12931	SRC	Y64	P69S	69	Missense	distal	5	no	21.521	21.343	PhosphoSitePlus	TCGA;ICGC;COSMIC	20.673	Down-regulation
TK_Src_SrcA_SRC_Y	P63000	RAC1	P12931	SRC	Y64	R68S	68	Missense	distal	4	no	21.521	21.547	PhosphoSitePlus	TCGA;ICGC;COSMIC	20.673	Up-regulation
TK_Src_SrcA_SRC_Y	P63000	RAC1	P12931	SRC	Y64	R68H	68	Missense	distal	4	no	21.521	21.534	PhosphoSitePlus	TCGA;ICGC;COSMIC	20.673	Up-regulation
TK_Src_SrcA_SRC_Y	P63000	RAC1	P12931	SRC	Y64	Q61R	61	Missense	distal	-3	no	21.521	20.904	PhosphoSitePlus	TCGA;ICGC;COSMIC	20.673	Down-regulation
TK_Src_SrcA_SRC_Y	P63000	RAC1	P12931	SRC	Y64	R68C	68	Missense	distal	4	no	21.521	21.522	PhosphoSitePlus	TCGA;ICGC;COSMIC	20.673	Up-regulation
TK_Src_SrcA_SRC_Y	P63000	RAC1	P12931	SRC	Y64	S71F	71	Missense	distal	7	no	21.521	21.548	PhosphoSitePlus	TCGA;ICGC;COSMIC	20.673	Up-regulation
TK_Src_SrcA_SRC_Y	P63000	RAC1	P12931	SRC	Y64	D63Y	63	Missense	proximal	-1	no	21.521	22.683	PhosphoSitePlus	TCGA;ICGC	20.673	Up-regulation
TK_Src_SrcA_SRC_Y	P63000	RAC1	P12931	SRC	Y64	D63H	63	Missense	proximal	-1	no	21.521	22.088	PhosphoSitePlus	TCGA;COSMIC	20.673	Up-regulation
TK_Src_SrcA_SRC_Y	P04049	RAF1	P12931	SRC	Y340	R333H	333	Missense	distal	-7	no	24.009	23.714	PhosphoSitePlus;EPSD	TCGA;COSMIC	20.673	Down-regulation
TK_Src_SrcA_SRC_Y	P04049	RAF1	P12931	SRC	Y340	S339I	339	Missense	proximal	-1	no	24.009	25.082	PhosphoSitePlus;EPSD	TCGA	20.673	Up-regulation
TK_Src_SrcA_SRC_Y	P04049	RAF1	P12931	SRC	Y341	S339I	339	Missense	proximal	-2	no	22.588	21.607	EPSD;PhosphoSitePlus	TCGA	20.673	Down-regulation
TK_Src_SrcA_SRC_Y	P51809	VAMP7	P12931	SRC	Y45	H47N	47	Missense	proximal	2	no	20.005	20.742	PhosphoSitePlus	TCGA;ICGC;COSMIC	20.673	Gain
TK_Src_SrcA_SRC_Y	Q12913	PTPRJ	P12931	SRC	Y1094	I1095M	1095	Missense	proximal	1	no	21.844	21.880	EPSD	TCGA;ICGC;COSMIC	20.673	Up-regulation
TK_Src_SrcA_SRC_Y	Q12913	PTPRJ	P12931	SRC	Y1094	A1097G	1097	Missense	distal	3	no	21.844	22.037	EPSD	TCGA;ICGC;COSMIC	20.673	Up-regulation
TK_Src_SrcA_SRC_Y	Q12913	PTPRJ	P12931	SRC	Y1268	V1265L	1265	Missense	distal	-3	no	21.912	21.101	EPSD	TCGA;ICGC;COSMIC	20.673	Down-regulation
TK_Src_SrcA_SRC_Y	Q12913	PTPRJ	P12931	SRC	Y1268	Y1272H	1272	Missense	distal	4	no	21.912	21.934	EPSD	TCGA;ICGC;COSMIC;GDSC;CCLE	20.673	Up-regulation
TK_Src_SrcA_SRC_Y	Q12913	PTPRJ	P12931	SRC	Y1268	R1275Q	1275	Missense	distal	7	no	21.912	21.870	EPSD	TCGA;ICGC;COSMIC	20.673	Down-regulation
TK_Src_SrcA_SRC_Y	Q12913	PTPRJ	P12931	SRC	Y1311	Q1312R	1312	Missense	proximal	1	no	20.784	19.792	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	20.673	Loss
TK_Src_SrcA_SRC_Y	O15350	TP73	P12931	SRC	Y28	S34L	34	Missense	distal	6	no	21.706	21.738	PhosphoSitePlus	TCGA;ICGC;COSMIC	20.673	Up-regulation
TK_Src_SrcA_SRC_Y	O15350	TP73	P12931	SRC	Y99	T105I	105	Missense	distal	6	no	20.647	20.676	EPSD	TCGA;ICGC;COSMIC	20.673	Gain
TK_Src_SrcA_SRC_Y	Q96KG7	MEGF10	P12931	SRC	Y1016	K1012N	1012	Missense	distal	-4	no	22.190	23.053	EPSD	TCGA;ICGC;COSMIC	20.673	Up-regulation
TK_Src_SrcA_SRC_Y	Q96KG7	MEGF10	P12931	SRC	Y1016	D1009N	1009	Missense	distal	-7	no	22.190	22.109	EPSD	TCGA;COSMIC	20.673	Down-regulation
TK_Src_SrcA_SRC_Y	Q96KG7	MEGF10	P12931	SRC	Y1016	C1021R	1021	Missense	distal	5	no	22.190	21.756	EPSD	TCGA;ICGC;COSMIC	20.673	Down-regulation
TK_Src_SrcA_SRC_Y	Q96KG7	MEGF10	P12931	SRC	Y1030	P1036L	1036	Missense	distal	6	no	21.659	21.675	PhosphoSitePlus	TCGA;ICGC;COSMIC	20.673	Up-regulation
TK_Src_SrcA_SRC_Y	Q96KG7	MEGF10	P12931	SRC	Y1061	A1062T	1062	Missense	proximal	1	no	22.793	22.338	EPSD	TCGA;ICGC;COSMIC	20.673	Down-regulation
TK_Src_SrcA_SRC_Y	Q96KG7	MEGF10	P12931	SRC	Y1061	S1067T	1067	Missense	distal	6	no	22.793	22.783	EPSD	TCGA;ICGC;COSMIC	20.673	Down-regulation
TK_Src_SrcA_SRC_Y	Q96KG7	MEGF10	P12931	SRC	Y1075	A1070V	1070	Missense	distal	-5	no	24.403	24.404	EPSD	TCGA;ICGC;COSMIC	20.673	Up-regulation
TK_Src_SrcA_SRC_Y	Q9P219	CCDC88C	P12931	SRC	Y1272	H1266R	1266	Missense	distal	-6	no	21.980	22.013	EPSD	TCGA;ICGC;COSMIC	20.673	Up-regulation
TK_Src_SrcA_SRC_Y	Q9P219	CCDC88C	P12931	SRC	Y1272	K1269R	1269	Missense	distal	-3	no	21.980	22.195	EPSD	TCGA;ICGC;COSMIC	20.673	Up-regulation
TK_Src_SrcA_SRC_Y	Q9P219	CCDC88C	P12931	SRC	Y1272	A1277T	1277	Missense	distal	5	no	21.980	22.195	EPSD	TCGA;ICGC;COSMIC	20.673	Up-regulation
TK_Src_SrcA_SRC_Y	P19404	NDUFV2	P12931	SRC	Y193	Y193C	193	Missense	central	0	yes	24.443	0.000	PhosphoSitePlus	TCGA;ICGC;COSMIC	20.673	Loss
TK_Src_SrcA_SRC_Y	P19404	NDUFV2	P12931	SRC	Y193	D195Y	195	Missense	proximal	2	no	24.443	24.463	PhosphoSitePlus	TCGA;ICGC;COSMIC	20.673	Up-regulation
TK_Src_SrcA_SRC_Y	P52789	HK2	P12931	SRC	Y112	P115S	115	Missense	distal	3	no	21.159	20.421	EPSD	TCGA;COSMIC	20.673	Loss
TK_Src_SrcA_SRC_Y	P52789	HK2	P12931	SRC	Y112	E106D	106	Missense	distal	-6	no	21.159	21.237	EPSD	TCGA	20.673	Up-regulation
TK_Src_SrcA_SRC_Y	Q13936	CACNA1C	P12931	SRC	Y1142	E1139Q	1139	Missense	distal	-3	no	20.948	20.068	EPSD	TCGA	20.673	Loss
TK_Src_SrcA_SRC_Y	Q13936	CACNA1C	P12931	SRC	Y1142	R1143C	1143	Missense	proximal	1	no	20.948	19.645	EPSD	TCGA;COSMIC	20.673	Loss
TK_Src_SrcA_SRC_Y	Q13936	CACNA1C	P12931	SRC	Y1142	E1135K	1135	Missense	distal	-7	no	20.948	20.785	EPSD	TCGA;COSMIC	20.673	Down-regulation
TK_Src_SrcA_SRC_Y	Q13936	CACNA1C	P12931	SRC	Y1142	T1149M	1149	Missense	distal	7	no	20.948	21.045	EPSD	TCGA;COSMIC	20.673	Up-regulation
TK_Src_SrcA_SRC_Y	Q13936	CACNA1C	P12931	SRC	Y1667	K1665N	1665	Missense	proximal	-2	no	20.055	20.848	EPSD	TCGA;COSMIC	20.673	Gain
TK_Src_SrcA_SRC_Y	Q13936	CACNA1C	P12931	SRC	Y1667	F1666L	1666	Missense	proximal	-1	no	20.055	20.915	EPSD	TCGA;COSMIC	20.673	Gain
TK_Src_SrcA_SRC_Y	Q13936	CACNA1C	P12931	SRC	Y1920	E1913K	1913	Missense	distal	-7	no	21.274	21.111	EPSD	TCGA;COSMIC	20.673	Down-regulation
TK_Src_SrcA_SRC_Y	P23743	DGKA	P12931	SRC	Y50	V43I	43	Missense	distal	-7	no	21.272	21.288	EPSD	TCGA;ICGC;COSMIC	20.673	Up-regulation
TK_Src_SrcA_SRC_Y	P23743	DGKA	P12931	SRC	Y50	A47V	47	Missense	distal	-3	no	21.272	20.721	EPSD	TCGA;ICGC	20.673	Down-regulation
TK_Src_SrcA_SRC_Y	P23743	DGKA	P12931	SRC	Y623	Q627E	627	Missense	distal	4	no	23.173	23.166	EPSD	TCGA;ICGC;COSMIC	20.673	Down-regulation
TK_Src_SrcA_SRC_Y	P23743	DGKA	P12931	SRC	Y623	G620E	620	Missense	distal	-3	no	23.173	23.777	EPSD	TCGA;ICGC;COSMIC	20.673	Up-regulation
TK_Src_SrcA_SRC_Y	P23743	DGKA	P12931	SRC	Y623	I622V	622	Missense	proximal	-1	no	23.173	23.548	EPSD	TCGA;ICGC;COSMIC	20.673	Up-regulation
TK_Src_SrcA_SRC_Y	P23743	DGKA	P12931	SRC	Y669	I668M	668	Missense	proximal	-1	no	21.351	20.120	EPSD	TCGA;ICGC;COSMIC	20.673	Loss
TK_Src_SrcA_SRC_Y	P03372	ESR1	P12931	SRC	Y537	L541Q	541	Missense	distal	4	no	21.208	21.196	PhosphoSitePlus	TCGA;ICGC;COSMIC	20.673	Down-regulation
TK_Src_SrcA_SRC_Y	P03372	ESR1	P12931	SRC	Y537	Y537H	537	Missense	central	0	yes	21.208	0.000	PhosphoSitePlus	TCGA;ICGC;COSMIC	20.673	Loss
TK_Src_SrcA_SRC_Y	P03372	ESR1	P12931	SRC	Y537	V533M	533	Missense	distal	-4	no	21.208	20.782	PhosphoSitePlus	TCGA;ICGC;COSMIC	20.673	Down-regulation
TK_Src_SrcA_SRC_Y	P03372	ESR1	P12931	SRC	Y537	D538G	538	Missense	proximal	1	no	21.208	20.830	PhosphoSitePlus	TCGA;ICGC;COSMIC	20.673	Down-regulation
TK_Src_SrcA_SRC_Y	P03372	ESR1	P12931	SRC	Y537	Y537N	537	Missense	central	0	yes	21.208	0.000	PhosphoSitePlus	TCGA;ICGC;COSMIC	20.673	Loss
TK_Src_SrcA_SRC_Y	P03372	ESR1	P12931	SRC	Y537	Y537S	537	Missense	central	0	yes	21.208	0.000	PhosphoSitePlus	TCGA;ICGC;COSMIC	20.673	Loss
TK_Src_SrcA_SRC_Y	P18827	SDC1	P12931	SRC	Y299	Y299F	299	Missense	central	0	yes	20.945	0.000	EPSD	TCGA;ICGC;COSMIC	20.673	Loss
TK_Src_SrcA_SRC_Y	P18827	SDC1	P12931	SRC	Y299	N295S	295	Missense	distal	-4	no	20.945	20.530	EPSD	TCGA;ICGC;COSMIC	20.673	Loss
TK_Src_SrcA_SRC_Y	Q9UKW4	VAV3	P12931	SRC	Y173	Y173S	173	Missense	central	0	yes	24.937	0.000	PhosphoSitePlus	TCGA;ICGC;COSMIC	20.673	Loss
TK_Src_SrcA_SRC_Y	Q9UKW4	VAV3	P12931	SRC	Y173	D167N	167	Missense	distal	-6	no	24.937	24.747	PhosphoSitePlus	TCGA;ICGC;COSMIC	20.673	Down-regulation
TK_Src_SrcA_SRC_Y	Q9UKW4	VAV3	P12931	SRC	Y207	E209D	209	Missense	proximal	2	no	21.098	20.810	EPSD	TCGA;ICGC;COSMIC	20.673	Down-regulation
TK_Src_SrcA_SRC_Y	Q9UKW4	VAV3	P12931	SRC	Y265	Q262K	262	Missense	distal	-3	no	23.288	22.456	EPSD	TCGA;COSMIC	20.673	Down-regulation
TK_Src_SrcA_SRC_Y	Q9UKW4	VAV3	P12931	SRC	Y265	V267I	267	Missense	proximal	2	no	23.288	22.093	EPSD	TCGA;ICGC	20.673	Down-regulation
TK_Src_SrcA_SRC_Y	Q9UKW4	VAV3	P12931	SRC	Y278	L275S	275	Missense	distal	-3	no	19.515	21.783	EPSD	TCGA;COSMIC	20.673	Gain
TK_Src_SrcA_SRC_Y	Q9UKW4	VAV3	P12931	SRC	Y706	E705G	705	Missense	proximal	-1	no	21.623	20.156	EPSD	TCGA	20.673	Loss
TK_Src_SrcA_SRC_Y	Q9UKW4	VAV3	P12931	SRC	Y706	E705K	705	Missense	proximal	-1	no	21.623	19.715	EPSD	TCGA;ICGC;COSMIC	20.673	Loss
TK_Src_SrcA_SRC_Y	P61586	RHOA	P12931	SRC	Y66	Q63K	63	Missense	distal	-3	no	20.795	19.964	PhosphoSitePlus;EPSD	TCGA;ICGC;COSMIC	20.673	Loss
TK_Src_SrcA_SRC_Y	P61586	RHOA	P12931	SRC	Y66	L69P	69	Missense	distal	3	no	20.795	20.893	PhosphoSitePlus;EPSD	TCGA;ICGC;COSMIC;GDSC;CCLE	20.673	Up-regulation
TK_Src_SrcA_SRC_Y	P61586	RHOA	P12931	SRC	Y66	D59G	59	Missense	distal	-7	no	20.795	20.373	PhosphoSitePlus;EPSD	TCGA;COSMIC	20.673	Loss
TK_Src_SrcA_SRC_Y	P61586	RHOA	P12931	SRC	Y66	E64Q	64	Missense	proximal	-2	no	20.795	19.605	PhosphoSitePlus;EPSD	TCGA	20.673	Loss
TK_Src_SrcA_SRC_Y	P61586	RHOA	P12931	SRC	Y66	R68C	68	Missense	proximal	2	no	20.795	20.195	PhosphoSitePlus;EPSD	TCGA;ICGC;COSMIC	20.673	Loss
TK_Src_SrcA_SRC_Y	P61586	RHOA	P12931	SRC	Y66	G62E	62	Missense	distal	-4	no	20.795	21.228	PhosphoSitePlus;EPSD	TCGA;ICGC;COSMIC;CCLE	20.673	Up-regulation
TK_Src_SrcA_SRC_Y	P61586	RHOA	P12931	SRC	Y66	R70S	70	Missense	distal	4	no	20.795	20.821	PhosphoSitePlus;EPSD	TCGA;ICGC;COSMIC	20.673	Up-regulation
TK_Src_SrcA_SRC_Y	P61586	RHOA	P12931	SRC	Y66	D59N	59	Missense	distal	-7	no	20.795	20.715	PhosphoSitePlus;EPSD	TCGA;ICGC;COSMIC	20.673	Down-regulation
TK_Src_SrcA_SRC_Y	P61586	RHOA	P12931	SRC	Y66	Y66N	66	Missense	central	0	yes	20.795	0.000	PhosphoSitePlus;EPSD	TCGA;ICGC;COSMIC	20.673	Loss
TK_Src_SrcA_SRC_Y	P61586	RHOA	P12931	SRC	Y66	S73F	73	Missense	distal	7	no	20.795	20.822	PhosphoSitePlus;EPSD	TCGA;ICGC;COSMIC;CCLE	20.673	Up-regulation
TK_Src_SrcA_SRC_Y	P61586	RHOA	P12931	SRC	Y66	S73P	73	Missense	distal	7	no	20.795	20.815	PhosphoSitePlus;EPSD	TCGA;ICGC;COSMIC	20.673	Up-regulation
TK_Src_SrcA_SRC_Y	P61586	RHOA	P12931	SRC	Y66	T60K	60	Missense	distal	-6	no	20.795	20.921	PhosphoSitePlus;EPSD	TCGA;ICGC;COSMIC	20.673	Up-regulation
TK_Src_SrcA_SRC_Y	P61586	RHOA	P12931	SRC	Y66	D59Y	59	Missense	distal	-7	no	20.795	20.345	PhosphoSitePlus;EPSD	TCGA;ICGC;COSMIC	20.673	Loss
TK_Src_SrcA_SRC_Y	P61586	RHOA	P12931	SRC	Y66	L69M	69	Missense	distal	3	no	20.795	20.402	PhosphoSitePlus;EPSD	TCGA;ICGC;COSMIC;CCLE	20.673	Loss
TK_Src_SrcA_SRC_Y	P61586	RHOA	P12931	SRC	Y66	A61D	61	Missense	distal	-5	no	20.795	20.977	PhosphoSitePlus;EPSD	TCGA;ICGC;COSMIC	20.673	Up-regulation
TK_Src_SrcA_SRC_Y	P61586	RHOA	P12931	SRC	Y66	G62R	62	Missense	distal	-4	no	20.795	20.777	PhosphoSitePlus;EPSD	TCGA;ICGC;COSMIC	20.673	Down-regulation
TK_Src_SrcA_SRC_Y	P07949	RET	P12931	SRC	Y809	R813W	813	Missense	distal	4	no	20.746	20.718	EPSD	TCGA;ICGC	20.673	Down-regulation
TK_Src_SrcA_SRC_Y	P07949	RET	P12931	SRC	Y809	A807T	807	Missense	proximal	-2	no	20.746	20.874	EPSD	TCGA;ICGC;COSMIC	20.673	Up-regulation
TK_Src_SrcA_SRC_Y	P07949	RET	P12931	SRC	Y900	E901K	901	Missense	proximal	1	no	22.850	20.455	EPSD	TCGA;ICGC;COSMIC	20.673	Loss
TK_Src_SrcA_SRC_Y	P07949	RET	P12931	SRC	Y900	G894S	894	Missense	distal	-6	no	22.850	22.993	EPSD	TCGA;ICGC;COSMIC	20.673	Up-regulation
TK_Src_SrcA_SRC_Y	P07949	RET	P12931	SRC	Y900	K907T	907	Missense	distal	7	no	22.850	22.808	EPSD	TCGA;ICGC;COSMIC	20.673	Down-regulation
TK_Src_SrcA_SRC_Y	P07949	RET	P12931	SRC	Y905	E901K	901	Missense	distal	-4	no	24.148	22.978	PhosphoSitePlus	TCGA;ICGC;COSMIC	20.673	Down-regulation
TK_Src_SrcA_SRC_Y	P07949	RET	P12931	SRC	Y905	R912W	912	Missense	distal	7	no	24.148	24.244	PhosphoSitePlus	TCGA;ICGC;COSMIC	20.673	Up-regulation
TK_Src_SrcA_SRC_Y	P07949	RET	P12931	SRC	Y905	R912Q	912	Missense	distal	7	no	24.148	24.105	PhosphoSitePlus	TCGA;ICGC;COSMIC	20.673	Down-regulation
TK_Src_SrcA_SRC_Y	P07949	RET	P12931	SRC	Y905	K907T	907	Missense	proximal	2	no	24.148	25.232	PhosphoSitePlus	TCGA;ICGC;COSMIC	20.673	Up-regulation
TK_Src_SrcA_SRC_Y	P07949	RET	P12931	SRC	Y1029	G1032D	1032	Missense	distal	3	no	22.382	22.009	EPSD	TCGA;ICGC;COSMIC	20.673	Down-regulation
TK_Src_SrcA_SRC_Y	P07949	RET	P12931	SRC	Y1062	N1059D	1059	Missense	distal	-3	no	21.549	22.057	EPSD	TCGA;ICGC;COSMIC	20.673	Up-regulation
TK_Src_SrcA_SRC_Y	P07949	RET	P12931	SRC	Y1096	L1101V	1101	Missense	distal	5	no	22.266	22.171	EPSD	TCGA;ICGC;COSMIC;GDSC;CCLE	20.673	Down-regulation
TK_Src_SrcA_SRC_Y	P07949	RET	P12931	SRC	Y1096	D1093G	1093	Missense	distal	-3	no	22.266	21.618	EPSD	TCGA;ICGC;COSMIC	20.673	Down-regulation
TK_Src_SrcA_SRC_Y	P07949	RET	P12931	SRC	Y1096	D1093N	1093	Missense	distal	-3	no	22.266	21.758	EPSD	TCGA;ICGC;COSMIC	20.673	Down-regulation
TK_Src_SrcA_SRC_Y	P07949	RET	P12931	SRC	Y1096	N1092H	1092	Missense	distal	-4	no	22.266	21.638	EPSD	TCGA;ICGC	20.673	Down-regulation
TK_Src_SrcA_SRC_Y	Q92529	SHC3	P12931	SRC	Y341	H339Q	339	Missense	proximal	-2	no	22.240	22.119	EPSD	TCGA;ICGC;COSMIC	20.673	Down-regulation
TK_Src_SrcA_SRC_Y	Q92529	SHC3	P12931	SRC	Y341	S347I	347	Missense	distal	6	no	22.240	22.260	EPSD	TCGA;ICGC	20.673	Up-regulation
TK_Src_SrcA_SRC_Y	Q92529	SHC3	P12931	SRC	Y342	H339Q	339	Missense	distal	-3	no	22.964	23.616	EPSD	TCGA;ICGC;COSMIC	20.673	Up-regulation
TK_Src_SrcA_SRC_Y	Q92529	SHC3	P12931	SRC	Y342	S347I	347	Missense	distal	5	no	22.964	23.111	EPSD	TCGA;ICGC	20.673	Up-regulation
TK_Src_SrcA_SRC_Y	Q92529	SHC3	P12931	SRC	Y379	G386E	386	Missense	distal	7	no	22.159	22.136	EPSD	TCGA;ICGC;COSMIC	20.673	Down-regulation
TK_Src_SrcA_SRC_Y	Q92529	SHC3	P12931	SRC	Y379	E376K	376	Missense	distal	-3	no	22.159	20.448	EPSD	TCGA;ICGC;COSMIC	20.673	Loss
TK_Src_SrcA_SRC_Y	Q92529	SHC3	P12931	SRC	Y379	L385S	385	Missense	distal	6	no	22.159	22.127	EPSD	TCGA;ICGC;COSMIC	20.673	Down-regulation
TK_Src_SrcA_SRC_Y	Q92529	SHC3	P12931	SRC	Y380	G386E	386	Missense	distal	6	no	20.950	20.959	EPSD	TCGA;ICGC;COSMIC	20.673	Up-regulation
TK_Src_SrcA_SRC_Y	Q92529	SHC3	P12931	SRC	Y380	E376K	376	Missense	distal	-4	no	20.950	19.780	EPSD	TCGA;ICGC;COSMIC	20.673	Loss
TK_Src_SrcA_SRC_Y	Q92529	SHC3	P12931	SRC	Y380	L385S	385	Missense	distal	5	no	20.950	20.758	EPSD	TCGA;ICGC;COSMIC	20.673	Down-regulation
TK_Src_SrcA_SRC_Y	Q92529	SHC3	P12931	SRC	Y406	D404N	404	Missense	proximal	-2	no	25.471	25.191	EPSD	TCGA;ICGC;COSMIC	20.673	Down-regulation
TK_Src_SrcA_SRC_Y	Q92529	SHC3	P12931	SRC	Y406	S402F	402	Missense	distal	-4	no	25.471	24.552	EPSD	TCGA;ICGC;COSMIC	20.673	Down-regulation
TK_Src_SrcA_SRC_Y	Q92529	SHC3	P12931	SRC	Y406	D404G	404	Missense	proximal	-2	no	25.471	25.181	EPSD	TCGA;ICGC	20.673	Down-regulation
TK_Src_SrcA_SRC_Y	Q92529	SHC3	P12931	SRC	Y424	T418A	418	Missense	distal	-6	no	23.493	23.456	EPSD	TCGA;ICGC;COSMIC	20.673	Down-regulation
TK_Src_SrcA_SRC_Y	Q92529	SHC3	P12931	SRC	Y424	T418M	418	Missense	distal	-6	no	23.493	23.005	EPSD	TCGA;ICGC;COSMIC	20.673	Down-regulation
TK_Src_SrcA_SRC_Y	P23528	CFL1	P12931	SRC	Y68	D65N	65	Missense	distal	-3	no	22.250	21.742	PhosphoSitePlus	TCGA;COSMIC	20.673	Down-regulation
TK_Src_SrcA_SRC_Y	P23528	CFL1	P12931	SRC	Y85	A83T	83	Missense	proximal	-2	no	20.579	20.708	EPSD	TCGA;COSMIC	20.673	Gain
TK_Src_SrcA_SRC_Y	P23528	CFL1	P12931	SRC	Y140	R146C	146	Missense	distal	6	no	22.300	22.380	EPSD	TCGA;COSMIC	20.673	Up-regulation
TK_Src_SrcA_SRC_Y	P50402	EMD	P12931	SRC	Y74	E80Q	80	Missense	distal	6	no	24.147	24.130	PhosphoSitePlus;EPSD	TCGA;ICGC;COSMIC	20.673	Down-regulation
TK_Src_SrcA_SRC_Y	P50402	EMD	P12931	SRC	Y74	A71S	71	Missense	distal	-3	no	24.147	25.053	PhosphoSitePlus;EPSD	TCGA;ICGC;COSMIC	20.673	Up-regulation
TK_Src_SrcA_SRC_Y	P50402	EMD	P12931	SRC	Y94	S87I	87	Missense	distal	-7	no	23.020	22.764	EPSD	TCGA;ICGC;COSMIC	20.673	Down-regulation
TK_Src_SrcA_SRC_Y	P50402	EMD	P12931	SRC	Y94	G89C	89	Missense	distal	-5	no	23.020	22.285	EPSD	TCGA	20.673	Down-regulation
TK_Src_SrcA_SRC_Y	P50402	EMD	P12931	SRC	Y95	G89C	89	Missense	distal	-6	no	25.691	25.297	EPSD;PhosphoSitePlus	TCGA	20.673	Down-regulation
TK_Src_SrcA_SRC_Y	P50402	EMD	P12931	SRC	Y161	R157Q	157	Missense	distal	-4	no	23.589	23.210	EPSD	TCGA;ICGC;COSMIC	20.673	Down-regulation
TK_Src_SrcA_SRC_Y	P50402	EMD	P12931	SRC	Y161	R157W	157	Missense	distal	-4	no	23.589	22.216	EPSD	TCGA;ICGC;COSMIC	20.673	Down-regulation
TK_Src_SrcA_SRC_Y	P05023	ATP1A1	P12931	SRC	Y10	R7H	7	Missense	distal	-3	no	21.659	21.624	EPSD	TCGA	20.673	Down-regulation
TK_Src_SrcA_SRC_Y	P05023	ATP1A1	P12931	SRC	Y902	D897N	897	Missense	distal	-5	no	20.791	20.579	EPSD	TCGA;ICGC;COSMIC	20.673	Loss
TK_Src_SrcA_SRC_Y	P05023	ATP1A1	P12931	SRC	Y902	Q904H	904	Missense	proximal	2	no	20.791	20.289	EPSD	TCGA;ICGC;COSMIC	20.673	Loss
TK_Src_SrcA_SRC_Y	P37173	TGFBR2	P12931	SRC	Y448	M450I	450	Missense	proximal	2	no	22.187	21.257	EPSD	TCGA;ICGC;COSMIC	20.673	Down-regulation
TK_Src_SrcA_SRC_Y	P37173	TGFBR2	P12931	SRC	Y448	A451T	451	Missense	distal	3	no	22.187	22.231	EPSD	TCGA;COSMIC	20.673	Up-regulation
TK_Src_SrcA_SRC_Y	P37173	TGFBR2	P12931	SRC	Y448	M450V	450	Missense	proximal	2	no	22.187	22.452	EPSD	TCGA	20.673	Up-regulation
TK_Src_SrcA_SRC_Y	Q9H2X6	HIPK2	P12931	SRC	Y367	E371Q	371	Missense	distal	4	no	22.388	22.396	EPSD	TCGA;ICGC;COSMIC	20.673	Up-regulation
TK_Src_SrcA_SRC_Y	Q9H2X6	HIPK2	P12931	SRC	Y367	P370S	370	Missense	distal	3	no	22.388	21.649	EPSD	TCGA;ICGC;COSMIC	20.673	Down-regulation
TK_Src_SrcA_SRC_Y	O15379	HDAC3	P12931	SRC	Y325	E330K	330	Missense	distal	5	no	21.584	21.617	PhosphoSitePlus	TCGA;ICGC;COSMIC	20.673	Up-regulation
TK_Src_SrcA_SRC_Y	O15379	HDAC3	P12931	SRC	Y325	A318T	318	Missense	distal	-7	no	21.584	22.004	PhosphoSitePlus	TCGA;ICGC	20.673	Up-regulation
TK_Src_SrcA_SRC_Y	P53801	PTTG1IP	P12931	SRC	Y174	K169N	169	Missense	distal	-5	no	22.321	22.585	PhosphoSitePlus	TCGA;COSMIC	20.673	Up-regulation
TK_Src_SrcA_SRC_Y	Q9Y446	PKP3	P12931	SRC	Y84	Q83K	83	Missense	proximal	-1	no	21.024	19.521	EPSD	TCGA	20.673	Loss
TK_Src_SrcA_SRC_Y	Q9Y446	PKP3	P12931	SRC	Y390	D394G	394	Missense	distal	4	no	21.488	21.448	EPSD	TCGA;ICGC;COSMIC	20.673	Down-regulation
TK_Src_SrcA_SRC_Y	Q9Y446	PKP3	P12931	SRC	Y390	D391Y	391	Missense	proximal	1	no	21.488	21.090	EPSD	TCGA;ICGC;COSMIC	20.673	Down-regulation
TK_Src_SrcA_SRC_Y	Q9Y446	PKP3	P12931	SRC	Y390	A393T	393	Missense	distal	3	no	21.488	21.532	EPSD	TCGA;ICGC;COSMIC;GDSC;CCLE	20.673	Up-regulation
TK_Src_SrcA_SRC_Y	P31040	SDHA	P12931	SRC	Y169	R162T	162	Missense	distal	-7	no	23.239	23.087	EPSD	TCGA;COSMIC	20.673	Down-regulation
TK_Src_SrcA_SRC_Y	P31040	SDHA	P12931	SRC	Y169	R171H	171	Missense	proximal	2	no	23.239	23.087	EPSD	TCGA;COSMIC;GDSC;CCLE	20.673	Down-regulation
TK_Src_SrcA_SRC_Y	O14746	TERT	P12931	SRC	Y949	R951Q	951	Missense	proximal	2	no	21.333	21.682	EPSD	TCGA;COSMIC	20.673	Up-regulation
TK_Src_SrcA_SRC_Y	O43597	SPRY2	P12931	SRC	Y55	R50Q	50	Missense	distal	-5	no	22.341	22.182	PhosphoSitePlus	TCGA;ICGC;COSMIC	20.673	Down-regulation
TK_Src_SrcA_SRC_Y	O43597	SPRY2	P12931	SRC	Y55	G58W	58	Missense	distal	3	no	22.341	20.959	PhosphoSitePlus	TCGA;ICGC;COSMIC	20.673	Down-regulation
TK_Src_SrcA_SRC_Y	O43597	SPRY2	P12931	SRC	Y55	A48G	48	Missense	distal	-7	no	22.341	22.291	PhosphoSitePlus	TCGA;ICGC;COSMIC	20.673	Down-regulation
TK_Src_SrcA_SRC_Y	O43597	SPRY2	P12931	SRC	Y55	E57G	57	Missense	proximal	2	no	22.341	21.386	PhosphoSitePlus	TCGA;ICGC;COSMIC	20.673	Down-regulation
TK_Src_SrcA_SRC_Y	Q15746	MYLK	P12931	SRC	Y464	E458K	458	Missense	distal	-6	no	22.458	22.446	PhosphoSitePlus;EPSD	TCGA;ICGC;COSMIC	20.673	Down-regulation
TK_Src_SrcA_SRC_Y	Q15746	MYLK	P12931	SRC	Y464	G468D	468	Missense	distal	4	no	22.458	22.499	PhosphoSitePlus;EPSD	TCGA;ICGC;GDSC;CCLE	20.673	Up-regulation
TK_Src_SrcA_SRC_Y	Q15746	MYLK	P12931	SRC	Y846	G842S	842	Missense	distal	-4	no	21.336	21.048	EPSD	TCGA;ICGC;COSMIC	20.673	Down-regulation
TK_Src_SrcA_SRC_Y	P37840	SNCA	P12931	SRC	Y125	P120S	120	Missense	distal	-5	no	23.320	23.422	PhosphoSitePlus	TCGA;ICGC;COSMIC	20.673	Up-regulation
TK_Src_SrcA_SRC_Y	P37840	SNCA	P12931	SRC	Y125	S129F	129	Missense	distal	4	no	23.320	23.309	PhosphoSitePlus	TCGA;ICGC;COSMIC	20.673	Down-regulation
TK_Src_SrcA_SRC_Y	P37840	SNCA	P12931	SRC	Y136	D135Y	135	Missense	proximal	-1	no	20.221	21.383	EPSD	TCGA;ICGC;COSMIC	20.673	Gain
TK_Src_SrcA_SRC_Y	P57737	CORO7	P12931	SRC	Y615	R620S	620	Missense	distal	5	no	21.658	21.633	EPSD	TCGA;COSMIC	20.673	Down-regulation
TK_Src_SrcA_SRC_Y	P57737	CORO7	P12931	SRC	Y615	R620C	620	Missense	distal	5	no	21.658	22.091	EPSD	TCGA;COSMIC	20.673	Up-regulation
TK_Src_SrcA_SRC_Y	Q14289	PTK2B	P12931	SRC	Y402	I397L	397	Missense	distal	-5	no	22.034	22.082	PhosphoSitePlus	TCGA;ICGC;COSMIC	20.673	Up-regulation
TK_Src_SrcA_SRC_Y	Q14289	PTK2B	P12931	SRC	Y440	Y440C	440	Missense	central	0	yes	22.476	0.000	EPSD	TCGA;COSMIC	20.673	Loss
TK_Src_SrcA_SRC_Y	Q14289	PTK2B	P12931	SRC	Y440	H447Y	447	Missense	distal	7	no	22.476	22.438	EPSD	TCGA;ICGC;COSMIC	20.673	Down-regulation
TK_Src_SrcA_SRC_Y	Q14289	PTK2B	P12931	SRC	Y579	R586H	586	Missense	distal	7	no	26.652	26.638	EPSD	TCGA;COSMIC	20.673	Down-regulation
TK_Src_SrcA_SRC_Y	Q14289	PTK2B	P12931	SRC	Y579	A582S	582	Missense	distal	3	no	26.652	26.608	EPSD	TCGA	20.673	Down-regulation
TK_Src_SrcA_SRC_Y	Q14289	PTK2B	P12931	SRC	Y579	R586C	586	Missense	distal	7	no	26.652	26.725	EPSD	TCGA;ICGC;COSMIC	20.673	Up-regulation
TK_Src_SrcA_SRC_Y	Q14289	PTK2B	P12931	SRC	Y580	R586H	586	Missense	distal	6	no	23.910	23.939	EPSD	TCGA;COSMIC	20.673	Up-regulation
TK_Src_SrcA_SRC_Y	Q14289	PTK2B	P12931	SRC	Y580	A582S	582	Missense	proximal	2	no	23.910	24.262	EPSD	TCGA	20.673	Up-regulation
TK_Src_SrcA_SRC_Y	Q14289	PTK2B	P12931	SRC	Y580	R586C	586	Missense	distal	6	no	23.910	23.990	EPSD	TCGA;ICGC;COSMIC	20.673	Up-regulation
TK_Src_SrcA_SRC_Y	Q14289	PTK2B	P12931	SRC	Y722	R723S	723	Missense	proximal	1	no	19.994	20.873	EPSD	TCGA;ICGC;COSMIC	20.673	Gain
TK_Src_SrcA_SRC_Y	Q14289	PTK2B	P12931	SRC	Y834	M832T	832	Missense	proximal	-2	no	20.093	21.190	EPSD	TCGA	20.673	Gain
TK_Src_SrcA_SRC_Y	Q14289	PTK2B	P12931	SRC	Y849	G854W	854	Missense	distal	5	no	21.052	21.463	EPSD	TCGA;ICGC;COSMIC	20.673	Up-regulation
TK_Src_SrcA_SRC_Y	P18433	PTPRA	P12931	SRC	Y588	Y588F	588	Missense	central	0	yes	22.140	0.000	EPSD	TCGA;ICGC;COSMIC	20.673	Loss
TK_Src_SrcA_SRC_Y	P18433	PTPRA	P12931	SRC	Y588	R581W	581	Missense	distal	-7	no	22.140	21.667	EPSD	TCGA;COSMIC;GDSC	20.673	Down-regulation
TK_Src_SrcA_SRC_Y	P18433	PTPRA	P12931	SRC	Y588	A591T	591	Missense	distal	3	no	22.140	22.184	EPSD	TCGA;ICGC;COSMIC	20.673	Up-regulation
TK_Src_SrcA_SRC_Y	P18433	PTPRA	P12931	SRC	Y588	E583K	583	Missense	distal	-5	no	22.140	21.563	EPSD	TCGA;ICGC;COSMIC	20.673	Down-regulation
TK_Src_SrcA_SRC_Y	P10275	AR	P12931	SRC	Y225	K222N	222	Missense	distal	-3	no	19.542	20.791	EPSD	TCGA;ICGC;COSMIC	20.673	Gain
TK_Src_SrcA_SRC_Y	P10275	AR	P12931	SRC	Y269	R264W	264	Missense	distal	-5	no	21.045	20.380	EPSD	TCGA;ICGC;COSMIC	20.673	Loss
TK_Src_SrcA_SRC_Y	P10275	AR	P12931	SRC	Y269	A270T	270	Missense	proximal	1	no	21.045	20.591	EPSD	TCGA;ICGC;COSMIC;GDSC;CCLE	20.673	Loss
TK_Src_SrcA_SRC_Y	P10275	AR	P12931	SRC	Y309	E308K	308	Missense	proximal	-1	no	23.332	21.424	EPSD	TCGA;COSMIC	20.673	Down-regulation
TK_Src_SrcA_SRC_Y	P10275	AR	P12931	SRC	Y309	Y316H	316	Missense	distal	7	no	23.332	23.369	EPSD	TCGA;ICGC	20.673	Up-regulation
TK_Src_SrcA_SRC_Y	P10275	AR	P12931	SRC	Y364	S361N	361	Missense	distal	-3	no	21.254	21.214	EPSD	TCGA;ICGC;COSMIC	20.673	Down-regulation
TK_Src_SrcA_SRC_Y	P10275	AR	P12931	SRC	Y364	L371Q	371	Missense	distal	7	no	21.254	21.236	EPSD	TCGA;ICGC;COSMIC	20.673	Down-regulation
TK_Src_SrcA_SRC_Y	P10275	AR	P12931	SRC	Y364	L369V	369	Missense	distal	5	no	21.254	21.159	EPSD	TCGA;ICGC;COSMIC	20.673	Down-regulation
TK_Src_SrcA_SRC_Y	P10275	AR	P12931	SRC	Y365	S361N	361	Missense	distal	-4	no	20.577	20.992	EPSD	TCGA;ICGC;COSMIC	20.673	Gain
TK_Src_SrcA_SRC_Y	P10275	AR	P12931	SRC	Y535	E541Q	541	Missense	distal	6	no	22.172	22.154	PhosphoSitePlus	TCGA;ICGC;COSMIC	20.673	Down-regulation
TK_Src_SrcA_SRC_Y	P10275	AR	P12931	SRC	Y535	E541K	541	Missense	distal	6	no	22.172	22.170	PhosphoSitePlus	TCGA;ICGC;COSMIC	20.673	Down-regulation
TK_Src_SrcA_SRC_Y	P10275	AR	P12931	SRC	Y858	F857V	857	Missense	proximal	-1	no	19.697	21.666	EPSD	TCGA;ICGC;COSMIC	20.673	Gain
TK_Src_SrcA_SRC_Y	O14976	GAK	P12931	SRC	Y285	P280L	280	Missense	distal	-5	no	22.876	22.719	EPSD	TCGA;ICGC;COSMIC	20.673	Down-regulation
TK_Src_SrcA_SRC_Y	O14976	GAK	P12931	SRC	Y338	N335S	335	Missense	distal	-3	no	20.806	20.847	EPSD	TCGA;COSMIC	20.673	Up-regulation
TK_Src_SrcA_SRC_Y	O14976	GAK	P12931	SRC	Y338	A341T	341	Missense	distal	3	no	20.806	20.850	EPSD	TCGA;COSMIC;GDSC;CCLE	20.673	Up-regulation
TK_Src_SrcA_SRC_Y	O14976	GAK	P12931	SRC	Y371	D376E	376	Missense	distal	5	no	22.598	22.806	EPSD	TCGA	20.673	Up-regulation
TK_Src_SrcA_SRC_Y	O14976	GAK	P12931	SRC	Y371	Q369L	369	Missense	proximal	-2	no	22.598	21.854	EPSD	TCGA;ICGC;COSMIC	20.673	Down-regulation
TK_Src_SrcA_SRC_Y	O14976	GAK	P12931	SRC	Y764	A762T	762	Missense	proximal	-2	no	21.459	21.588	EPSD	TCGA;ICGC;COSMIC	20.673	Up-regulation
TK_Src_SrcA_SRC_Y	P02786	TFRC	P12931	SRC	Y402	A407S	407	Missense	distal	5	no	22.148	22.193	EPSD	TCGA;COSMIC	20.673	Up-regulation
TK_Src_SrcA_SRC_Y	O60331	PIP5K1C	P12931	SRC	Y649	D643N	643	Missense	distal	-6	no	21.315	21.125	PhosphoSitePlus	TCGA;ICGC	20.673	Down-regulation
TK_Src_SrcA_SRC_Y	O60331	PIP5K1C	P12931	SRC	Y649	E644D	644	Missense	distal	-5	no	21.315	21.214	PhosphoSitePlus	TCGA;ICGC;COSMIC	20.673	Down-regulation
TK_Src_SrcA_SRC_Y	O60331	PIP5K1C	P12931	SRC	Y649	Y654C	654	Missense	distal	5	no	21.315	21.359	PhosphoSitePlus	TCGA;ICGC;COSMIC	20.673	Up-regulation
TK_Src_SrcA_SRC_Y	O60331	PIP5K1C	P12931	SRC	Y649	H653Y	653	Missense	distal	4	no	21.315	21.293	PhosphoSitePlus	TCGA;ICGC;COSMIC	20.673	Down-regulation
TK_Src_SrcA_SRC_Y	O60331	PIP5K1C	P12931	SRC	Y649	Y649H	649	Missense	central	0	yes	21.315	0.000	PhosphoSitePlus	TCGA;ICGC;COSMIC	20.673	Loss
TK_Src_SrcA_SRC_Y	O60331	PIP5K1C	P12931	SRC	Y649	A656V	656	Missense	distal	7	no	21.315	21.391	PhosphoSitePlus	TCGA;ICGC;COSMIC;CCLE	20.673	Up-regulation
TK_Src_SrcA_SRC_Y	O60331	PIP5K1C	P12931	SRC	Y649	S646C	646	Missense	distal	-3	no	21.315	18.593	PhosphoSitePlus	TCGA;ICGC;COSMIC	20.673	Loss
TK_Src_SrcA_SRC_Y	P34741	SDC2	P12931	SRC	Y179	G182E	182	Missense	distal	3	no	21.440	21.162	PhosphoSitePlus	TCGA;COSMIC	20.673	Down-regulation
TK_Src_SrcA_SRC_Y	P34741	SDC2	P12931	SRC	Y179	R184L	184	Missense	distal	5	no	21.440	21.607	PhosphoSitePlus	TCGA	20.673	Up-regulation
TK_Src_SrcA_SRC_Y	Q92558	WASF1	P12931	SRC	Y125	D126N	126	Missense	proximal	1	no	20.803	19.411	PhosphoSitePlus	TCGA	20.673	Loss
TK_Src_SrcA_SRC_Y	P22001	KCNA3	P12931	SRC	Y162	I169V	169	Missense	distal	7	no	20.763	20.788	EPSD	TCGA;ICGC;COSMIC	20.673	Up-regulation
TK_Src_SrcA_SRC_Y	P22001	KCNA3	P12931	SRC	Y162	D157H	157	Missense	distal	-5	no	20.763	20.805	EPSD	TCGA;ICGC;COSMIC	20.673	Up-regulation
TK_Src_SrcA_SRC_Y	P22001	KCNA3	P12931	SRC	Y162	S165Y	165	Missense	distal	3	no	20.763	21.003	EPSD	TCGA;ICGC;COSMIC	20.673	Up-regulation
TK_Src_SrcA_SRC_Y	P22001	KCNA3	P12931	SRC	Y162	D157N	157	Missense	distal	-5	no	20.763	20.551	EPSD	TCGA;ICGC	20.673	Loss
TK_Src_SrcA_SRC_Y	P22001	KCNA3	P12931	SRC	Y162	G167D	167	Missense	distal	5	no	20.763	20.398	EPSD	TCGA;ICGC	20.673	Loss
TK_Src_SrcA_SRC_Y	P22001	KCNA3	P12931	SRC	Y162	L160I	160	Missense	proximal	-2	no	20.763	20.526	EPSD	TCGA	20.673	Loss
TK_Src_SrcA_SRC_Y	P22001	KCNA3	P12931	SRC	Y499	E492G	492	Missense	distal	-7	no	21.715	21.264	PhosphoSitePlus;EPSD	TCGA;ICGC;COSMIC	20.673	Down-regulation
TK_Src_SrcA_SRC_Y	A1X283	SH3PXD2B	P12931	SRC	Y42	R43W	43	Missense	proximal	1	no	23.015	22.932	EPSD	TCGA;ICGC;COSMIC	20.673	Down-regulation
TK_Src_SrcA_SRC_Y	A1X283	SH3PXD2B	P12931	SRC	Y42	R44H	44	Missense	proximal	2	no	23.015	22.863	EPSD	TCGA;ICGC;COSMIC;CCLE	20.673	Down-regulation
TK_Src_SrcA_SRC_Y	A1X283	SH3PXD2B	P12931	SRC	Y373	A377T	377	Missense	distal	4	no	22.361	22.356	EPSD	TCGA;ICGC;COSMIC	20.673	Down-regulation
TK_Src_SrcA_SRC_Y	A1X283	SH3PXD2B	P12931	SRC	Y373	Y373C	373	Missense	central	0	yes	22.361	0.000	EPSD	TCGA;ICGC;COSMIC	20.673	Loss
TK_Src_SrcA_SRC_Y	A1X283	SH3PXD2B	P12931	SRC	Y373	E378K	378	Missense	distal	5	no	22.361	22.393	EPSD	TCGA;ICGC;COSMIC	20.673	Up-regulation
TK_Src_SrcA_SRC_Y	A1X283	SH3PXD2B	P12931	SRC	Y374	A377T	377	Missense	distal	3	no	23.334	23.378	EPSD	TCGA;ICGC;COSMIC	20.673	Up-regulation
TK_Src_SrcA_SRC_Y	A1X283	SH3PXD2B	P12931	SRC	Y374	Y373C	373	Missense	proximal	-1	no	23.334	22.265	EPSD	TCGA;ICGC;COSMIC	20.673	Down-regulation
TK_Src_SrcA_SRC_Y	A1X283	SH3PXD2B	P12931	SRC	Y374	E378K	378	Missense	distal	4	no	23.334	23.335	EPSD	TCGA;ICGC;COSMIC	20.673	Up-regulation
TK_Src_SrcA_SRC_Y	A1X283	SH3PXD2B	P12931	SRC	Y855	D860N	860	Missense	distal	5	no	21.160	21.317	EPSD	TCGA;ICGC;COSMIC	20.673	Up-regulation
TK_Src_SrcA_SRC_Y	P06493	CDK1	P12931	SRC	Y15	K9R	9	Missense	distal	-6	no	24.693	24.479	PhosphoSitePlus	TCGA;ICGC;COSMIC	20.673	Down-regulation
TK_Src_SrcA_SRC_Y	P06493	CDK1	P12931	SRC	Y181	R180H	180	Missense	proximal	-1	no	20.616	22.511	EPSD	TCGA;ICGC;COSMIC	20.673	Gain
TK_Src_SrcA_SRC_Y	P22681	CBL	P12931	SRC	Y141	R139I	139	Missense	proximal	-2	no	21.202	20.966	EPSD	TCGA;ICGC;COSMIC	20.673	Down-regulation
TK_Src_SrcA_SRC_Y	P22681	CBL	P12931	SRC	Y141	E143D	143	Missense	proximal	2	no	21.202	20.914	EPSD	TCGA;ICGC	20.673	Down-regulation
TK_Src_SrcA_SRC_Y	P22681	CBL	P12931	SRC	Y368	Q367H	367	Missense	proximal	-1	no	22.291	22.355	EPSD	TCGA;ICGC;COSMIC	20.673	Up-regulation
TK_Src_SrcA_SRC_Y	P22681	CBL	P12931	SRC	Y368	L370S	370	Missense	proximal	2	no	22.291	23.355	EPSD	TCGA;ICGC	20.673	Up-regulation
TK_Src_SrcA_SRC_Y	P22681	CBL	P12931	SRC	Y371	Q367H	367	Missense	distal	-4	no	20.828	20.723	EPSD	TCGA;ICGC;COSMIC	20.673	Down-regulation
TK_Src_SrcA_SRC_Y	P22681	CBL	P12931	SRC	Y371	L370S	370	Missense	proximal	-1	no	20.828	20.490	EPSD	TCGA;ICGC	20.673	Loss
TK_Src_SrcA_SRC_Y	P22681	CBL	P12931	SRC	Y455	Y455N	455	Missense	central	0	yes	20.772	0.000	EPSD	TCGA	20.673	Loss
TK_Src_SrcA_SRC_Y	P22681	CBL	P12931	SRC	Y552	R559Q	559	Missense	distal	7	no	22.252	22.209	EPSD	TCGA;COSMIC	20.673	Down-regulation
TK_Src_SrcA_SRC_Y	P22681	CBL	P12931	SRC	Y552	P546L	546	Missense	distal	-6	no	22.252	22.232	EPSD	TCGA;ICGC;COSMIC	20.673	Down-regulation
TK_Src_SrcA_SRC_Y	P22681	CBL	P12931	SRC	Y552	S558P	558	Missense	distal	6	no	22.252	22.268	EPSD	TCGA;ICGC	20.673	Up-regulation
TK_Src_SrcA_SRC_Y	P22681	CBL	P12931	SRC	Y674	S675F	675	Missense	proximal	1	no	21.059	19.181	EPSD	TCGA;ICGC;COSMIC	20.673	Loss
TK_Src_SrcA_SRC_Y	P22681	CBL	P12931	SRC	Y674	S669Y	669	Missense	distal	-5	no	21.059	20.519	EPSD	TCGA;ICGC	20.673	Loss
TK_Src_SrcA_SRC_Y	P22681	CBL	P12931	SRC	Y674	A678D	678	Missense	distal	4	no	21.059	21.076	EPSD	TCGA;ICGC;COSMIC	20.673	Up-regulation
TK_Src_SrcA_SRC_Y	P22681	CBL	P12931	SRC	Y731	T730M	730	Missense	proximal	-1	no	22.875	22.623	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	20.673	Down-regulation
TK_Src_SrcA_SRC_Y	P22681	CBL	P12931	SRC	Y774	D772Y	772	Missense	proximal	-2	no	25.052	23.602	PhosphoSitePlus;EPSD	TCGA;ICGC;COSMIC	20.673	Down-regulation
TK_Src_SrcA_SRC_Y	P22681	CBL	P12931	SRC	Y774	D775V	775	Missense	proximal	1	no	25.052	23.776	PhosphoSitePlus;EPSD	TCGA;ICGC;COSMIC	20.673	Down-regulation
TK_Src_SrcA_SRC_Y	O14920	IKBKB	P12931	SRC	Y294	T293M	293	Missense	proximal	-1	no	24.919	24.666	EPSD	TCGA;COSMIC	20.673	Down-regulation
TK_Src_SrcA_SRC_Y	Q07954	LRP1	P12931	SRC	Y1937	Y1937C	1937	Missense	central	0	yes	22.490	0.000	EPSD	TCGA;ICGC;COSMIC	20.673	Loss
TK_Src_SrcA_SRC_Y	Q07954	LRP1	P12931	SRC	Y1937	D1940E	1940	Missense	distal	3	no	22.490	22.585	EPSD	TCGA;ICGC;COSMIC	20.673	Up-regulation
TK_Src_SrcA_SRC_Y	Q07954	LRP1	P12931	SRC	Y2000	R1999H	1999	Missense	proximal	-1	no	19.495	21.391	EPSD	TCGA;ICGC;COSMIC	20.673	Gain
TK_Src_SrcA_SRC_Y	Q07954	LRP1	P12931	SRC	Y4507	G4513R	4513	Missense	distal	6	no	23.612	23.586	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	20.673	Down-regulation
TK_Src_SrcA_SRC_Y	Q07954	LRP1	P12931	SRC	Y4507	G4513E	4513	Missense	distal	6	no	23.612	23.621	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	20.673	Up-regulation
TK_Src_SrcA_SRC_Y	Q16625	OCLN	P12931	SRC	Y29	G30C	30	Missense	proximal	1	no	21.526	19.229	EPSD	TCGA;ICGC;COSMIC	20.673	Loss
TK_Src_SrcA_SRC_Y	Q16625	OCLN	P12931	SRC	Y287	P292T	292	Missense	distal	5	no	21.127	21.120	EPSD	TCGA;ICGC;COSMIC	20.673	Down-regulation
TK_Src_SrcA_SRC_Y	Q16625	OCLN	P12931	SRC	Y287	V294I	294	Missense	distal	7	no	21.127	21.102	EPSD	TCGA;COSMIC	20.673	Down-regulation
TK_Src_SrcA_SRC_Y	Q16625	OCLN	P12931	SRC	Y342	S341F	341	Missense	proximal	-1	no	21.477	20.956	EPSD	TCGA;COSMIC	20.673	Down-regulation
TK_Src_SrcA_SRC_Y	Q16625	OCLN	P12931	SRC	Y342	P346L	346	Missense	distal	4	no	21.477	21.506	EPSD	TCGA;COSMIC	20.673	Up-regulation
TK_Src_SrcA_SRC_Y	Q16625	OCLN	P12931	SRC	Y368	G371D	371	Missense	distal	3	no	20.918	20.545	EPSD	TCGA;ICGC	20.673	Loss
TK_Src_SrcA_SRC_Y	Q16625	OCLN	P12931	SRC	Y368	D361H	361	Missense	distal	-7	no	20.918	20.822	EPSD	TCGA;ICGC;COSMIC	20.673	Down-regulation
TK_Src_SrcA_SRC_Y	Q16625	OCLN	P12931	SRC	Y398	G405D	405	Missense	distal	7	no	23.734	23.672	PhosphoSitePlus;EPSD	TCGA;ICGC;COSMIC	20.673	Down-regulation
TK_Src_SrcA_SRC_Y	Q16625	OCLN	P12931	SRC	Y398	R392I	392	Missense	distal	-6	no	23.734	23.852	PhosphoSitePlus;EPSD	TCGA;ICGC	20.673	Up-regulation
TK_Src_SrcA_SRC_Y	Q16625	OCLN	P12931	SRC	Y402	E407K	407	Missense	distal	5	no	20.644	20.677	EPSD;PhosphoSitePlus	TCGA;ICGC;GDSC;CCLE	20.673	Gain
TK_Src_SrcA_SRC_Y	Q99439	CNN2	P12931	SRC	Y303	E298D	298	Missense	distal	-5	no	21.700	21.600	EPSD	TCGA;COSMIC	20.673	Down-regulation
TK_Src_SrcA_SRC_Y	P16591	FER	P12931	SRC	Y42	K40T	40	Missense	proximal	-2	no	22.321	22.253	EPSD	TCGA;ICGC	20.673	Down-regulation
TK_Src_SrcA_SRC_Y	P16591	FER	P12931	SRC	Y714	R707H	707	Missense	distal	-7	no	28.525	28.230	PhosphoSitePlus	TCGA;ICGC;COSMIC	20.673	Down-regulation
TK_Src_SrcA_SRC_Y	P16591	FER	P12931	SRC	Y714	E709G	709	Missense	distal	-5	no	28.525	28.272	PhosphoSitePlus	TCGA;COSMIC	20.673	Down-regulation
TK_Src_SrcA_SRC_Y	P16591	FER	P12931	SRC	Y714	S716Y	716	Missense	proximal	2	no	28.525	28.084	PhosphoSitePlus	TCGA	20.673	Down-regulation
TK_Src_SrcA_SRC_Y	Q00610	CLTC	P12931	SRC	Y377	A370V	370	Missense	distal	-7	no	20.794	20.846	EPSD	TCGA;ICGC	20.673	Up-regulation
TK_Src_SrcA_SRC_Y	Q00610	CLTC	P12931	SRC	Y430	K429I	429	Missense	proximal	-1	no	20.016	22.074	EPSD	TCGA;ICGC;COSMIC	20.673	Gain
TK_Src_SrcA_SRC_Y	Q00610	CLTC	P12931	SRC	Y899	V904I	904	Missense	distal	5	no	24.562	24.612	EPSD	TCGA	20.673	Up-regulation
TK_Src_SrcA_SRC_Y	Q00610	CLTC	P12931	SRC	Y899	L894V	894	Missense	distal	-5	no	24.562	24.723	EPSD	TCGA;ICGC;COSMIC	20.673	Up-regulation
TK_Src_SrcA_SRC_Y	Q00610	CLTC	P12931	SRC	Y899	R895C	895	Missense	distal	-4	no	24.562	22.962	EPSD	TCGA;ICGC;COSMIC	20.673	Down-regulation
TK_Src_SrcA_SRC_Y	Q00610	CLTC	P12931	SRC	Y899	L894I	894	Missense	distal	-5	no	24.562	24.515	EPSD	TCGA;ICGC;COSMIC	20.673	Down-regulation
TK_Src_SrcA_SRC_Y	Q00610	CLTC	P12931	SRC	Y899	R903C	903	Missense	distal	4	no	24.562	24.563	EPSD	TCGA;ICGC;COSMIC	20.673	Up-regulation
TK_Src_SrcA_SRC_Y	Q00610	CLTC	P12931	SRC	Y899	R892I	892	Missense	distal	-7	no	24.562	24.058	EPSD	TCGA;ICGC;COSMIC	20.673	Down-regulation
TK_Src_SrcA_SRC_Y	Q00610	CLTC	P12931	SRC	Y899	Y900H	900	Missense	proximal	1	no	24.562	23.515	EPSD	TCGA;ICGC	20.673	Down-regulation
TK_Src_SrcA_SRC_Y	Q00610	CLTC	P12931	SRC	Y899	L894F	894	Missense	distal	-5	no	24.562	24.497	EPSD	TCGA;ICGC	20.673	Down-regulation
TK_Src_SrcA_SRC_Y	Q00610	CLTC	P12931	SRC	Y900	V904I	904	Missense	distal	4	no	23.371	23.382	EPSD	TCGA	20.673	Up-regulation
TK_Src_SrcA_SRC_Y	Q00610	CLTC	P12931	SRC	Y900	L894V	894	Missense	distal	-6	no	23.371	23.190	EPSD	TCGA;ICGC;COSMIC	20.673	Down-regulation
TK_Src_SrcA_SRC_Y	Q00610	CLTC	P12931	SRC	Y900	R895C	895	Missense	distal	-5	no	23.371	22.651	EPSD	TCGA;ICGC;COSMIC	20.673	Down-regulation
TK_Src_SrcA_SRC_Y	Q00610	CLTC	P12931	SRC	Y900	L894I	894	Missense	distal	-6	no	23.371	23.418	EPSD	TCGA;ICGC;COSMIC	20.673	Up-regulation
TK_Src_SrcA_SRC_Y	Q00610	CLTC	P12931	SRC	Y900	R903C	903	Missense	distal	3	no	23.371	23.583	EPSD	TCGA;ICGC;COSMIC	20.673	Up-regulation
TK_Src_SrcA_SRC_Y	Q00610	CLTC	P12931	SRC	Y900	Y900H	900	Missense	central	0	yes	23.371	0.000	EPSD	TCGA;ICGC	20.673	Loss
TK_Src_SrcA_SRC_Y	Q00610	CLTC	P12931	SRC	Y900	L894F	894	Missense	distal	-6	no	23.371	23.304	EPSD	TCGA;ICGC	20.673	Down-regulation
TK_Src_SrcA_SRC_Y	Q00610	CLTC	P12931	SRC	Y1168	K1163N	1163	Missense	distal	-5	no	21.336	21.599	EPSD	TCGA;COSMIC	20.673	Up-regulation
TK_Src_SrcA_SRC_Y	Q00610	CLTC	P12931	SRC	Y1168	A1164T	1164	Missense	distal	-4	no	21.336	21.610	EPSD	TCGA;COSMIC	20.673	Up-regulation
TK_Src_SrcA_SRC_Y	Q00610	CLTC	P12931	SRC	Y1206	R1204S	1204	Missense	proximal	-2	no	20.975	21.721	EPSD	TCGA;COSMIC	20.673	Up-regulation
TK_Src_SrcA_SRC_Y	Q00610	CLTC	P12931	SRC	Y1477	S1483L	1483	Missense	distal	6	no	22.715	22.747	PhosphoSitePlus	TCGA;COSMIC	20.673	Up-regulation
TK_Src_SrcA_SRC_Y	Q00610	CLTC	P12931	SRC	Y1477	L1470V	1470	Missense	distal	-7	no	22.715	22.679	PhosphoSitePlus	TCGA;ICGC;COSMIC	20.673	Down-regulation
TK_Src_SrcA_SRC_Y	Q00610	CLTC	P12931	SRC	Y1477	R1481Q	1481	Missense	distal	4	no	22.715	22.737	PhosphoSitePlus	TCGA;ICGC;COSMIC	20.673	Up-regulation
TK_Src_SrcA_SRC_Y	Q00610	CLTC	P12931	SRC	Y1634	P1631L	1631	Missense	distal	-3	no	20.961	19.811	EPSD	TCGA	20.673	Loss
TK_Src_SrcA_SRC_Y	Q9NZC7	WWOX	P12931	SRC	Y61	G62E	62	Missense	proximal	1	no	20.541	21.525	EPSD	TCGA;ICGC;COSMIC	20.673	Gain
TK_Src_SrcA_SRC_Y	Q9NZC7	WWOX	P12931	SRC	Y287	K284E	284	Missense	distal	-3	no	18.983	20.694	EPSD	TCGA;ICGC;COSMIC	20.673	Gain
TK_Src_SrcA_SRC_Y	P35637	FUS	P12931	SRC	Y239	R234H	234	Missense	distal	-5	no	20.602	20.812	EPSD	TCGA;COSMIC	20.673	Gain
TK_Src_SrcA_SRC_Y	P04637	TP53	P12931	SRC	Y220	Y220C	220	Missense	central	0	yes	22.082	0.000	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC;GDSC;CCLE	20.673	Loss
TK_Src_SrcA_SRC_Y	P04637	TP53	P12931	SRC	Y220	R213Q	213	Missense	distal	-7	no	22.082	21.857	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC;GDSC;CCLE	20.673	Down-regulation
TK_Src_SrcA_SRC_Y	P04637	TP53	P12931	SRC	Y220	H214R	214	Missense	distal	-6	no	22.082	22.115	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC;GDSC;CCLE	20.673	Up-regulation
TK_Src_SrcA_SRC_Y	P04637	TP53	P12931	SRC	Y220	V218E	218	Missense	proximal	-2	no	22.082	23.935	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	20.673	Up-regulation
TK_Src_SrcA_SRC_Y	P04637	TP53	P12931	SRC	Y220	E224D	224	Missense	distal	4	no	22.082	22.110	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC;GDSC	20.673	Up-regulation
TK_Src_SrcA_SRC_Y	P04637	TP53	P12931	SRC	Y220	Y220H	220	Missense	central	0	yes	22.082	0.000	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	20.673	Loss
TK_Src_SrcA_SRC_Y	P04637	TP53	P12931	SRC	Y220	S215I	215	Missense	distal	-5	no	22.082	21.776	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC;GDSC;CCLE	20.673	Down-regulation
TK_Src_SrcA_SRC_Y	P04637	TP53	P12931	SRC	Y220	V216M	216	Missense	distal	-4	no	22.082	21.656	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC;GDSC;CCLE	20.673	Down-regulation
TK_Src_SrcA_SRC_Y	P04637	TP53	P12931	SRC	Y220	Y220S	220	Missense	central	0	yes	22.082	0.000	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	20.673	Loss
TK_Src_SrcA_SRC_Y	P04637	TP53	P12931	SRC	Y220	S215N	215	Missense	distal	-5	no	22.082	21.954	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC;GDSC;CCLE	20.673	Down-regulation
TK_Src_SrcA_SRC_Y	P04637	TP53	P12931	SRC	Y220	V216G	216	Missense	distal	-4	no	22.082	22.898	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	20.673	Up-regulation
TK_Src_SrcA_SRC_Y	P04637	TP53	P12931	SRC	Y220	R213L	213	Missense	distal	-7	no	22.082	21.598	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC;GDSC;CCLE	20.673	Down-regulation
TK_Src_SrcA_SRC_Y	P04637	TP53	P12931	SRC	Y220	Y220D	220	Missense	central	0	yes	22.082	0.000	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC;GDSC;CCLE	20.673	Loss
TK_Src_SrcA_SRC_Y	P04637	TP53	P12931	SRC	Y220	V216E	216	Missense	distal	-4	no	22.082	23.331	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	20.673	Up-regulation
TK_Src_SrcA_SRC_Y	P04637	TP53	P12931	SRC	Y220	V218G	218	Missense	proximal	-2	no	22.082	23.358	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	20.673	Up-regulation
TK_Src_SrcA_SRC_Y	P04637	TP53	P12931	SRC	Y220	R213P	213	Missense	distal	-7	no	22.082	21.713	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	20.673	Down-regulation
TK_Src_SrcA_SRC_Y	P04637	TP53	P12931	SRC	Y220	H214L	214	Missense	distal	-6	no	22.082	22.186	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	20.673	Up-regulation
TK_Src_SrcA_SRC_Y	P04637	TP53	P12931	SRC	Y220	V216L	216	Missense	distal	-4	no	22.082	21.923	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC;GDSC;CCLE	20.673	Down-regulation
TK_Src_SrcA_SRC_Y	P04637	TP53	P12931	SRC	Y220	S215G	215	Missense	distal	-5	no	22.082	22.014	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC;GDSC;CCLE	20.673	Down-regulation
TK_Src_SrcA_SRC_Y	P04637	TP53	P12931	SRC	Y220	R213G	213	Missense	distal	-7	no	22.082	21.460	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	20.673	Down-regulation
TK_Src_SrcA_SRC_Y	P04637	TP53	P12931	SRC	Y220	S215R	215	Missense	distal	-5	no	22.082	21.998	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC;GDSC;CCLE	20.673	Down-regulation
TK_Src_SrcA_SRC_Y	P04637	TP53	P12931	SRC	Y327	K320E	320	Missense	distal	-7	no	20.561	20.724	EPSD	TCGA;ICGC;COSMIC	20.673	Gain
TK_Src_SrcA_SRC_Y	Q13283	G3BP1	P12931	SRC	Y20	Y20H	20	Missense	central	0	yes	20.808	0.000	EPSD	TCGA;ICGC;COSMIC;CCLE	20.673	Loss
TK_Src_SrcA_SRC_Y	Q13283	G3BP1	P12931	SRC	Y20	R13W	13	Missense	distal	-7	no	20.808	20.335	EPSD	TCGA;ICGC;COSMIC	20.673	Loss
TK_Src_SrcA_SRC_Y	Q13283	G3BP1	P12931	SRC	Y174	D169E	169	Missense	distal	-5	no	21.073	21.173	EPSD	TCGA;ICGC;COSMIC	20.673	Up-regulation
TK_Src_SrcA_SRC_Y	P11802	CDK4	P12931	SRC	Y17	R24L	24	Missense	distal	7	no	22.818	22.793	PhosphoSitePlus	TCGA;ICGC;COSMIC	20.673	Down-regulation
TK_Src_SrcA_SRC_Y	P11802	CDK4	P12931	SRC	Y17	A23S	23	Missense	distal	6	no	22.818	22.814	PhosphoSitePlus	TCGA;ICGC;COSMIC	20.673	Down-regulation
TK_Src_SrcA_SRC_Y	P11802	CDK4	P12931	SRC	Y17	G15R	15	Missense	proximal	-2	no	22.818	21.460	PhosphoSitePlus	TCGA;ICGC;COSMIC	20.673	Down-regulation
TK_Src_SrcA_SRC_Y	P11802	CDK4	P12931	SRC	Y17	K22M	22	Missense	distal	5	no	22.818	23.128	PhosphoSitePlus	TCGA;ICGC;COSMIC	20.673	Up-regulation
TK_Src_SrcA_SRC_Y	P11802	CDK4	P12931	SRC	Y17	R24H	24	Missense	distal	7	no	22.818	22.804	PhosphoSitePlus	TCGA;ICGC;COSMIC;GDSC;CCLE	20.673	Down-regulation
TK_Src_SrcA_SRC_Y	P11802	CDK4	P12931	SRC	Y17	R24S	24	Missense	distal	7	no	22.818	22.780	PhosphoSitePlus	TCGA;ICGC;COSMIC	20.673	Down-regulation
TK_Src_SrcA_SRC_Y	P11802	CDK4	P12931	SRC	Y17	R24C	24	Missense	distal	7	no	22.818	22.890	PhosphoSitePlus	TCGA;ICGC;COSMIC;GDSC;CCLE	20.673	Up-regulation
TK_Src_SrcA_SRC_Y	P11802	CDK4	P12931	SRC	Y17	K22Q	22	Missense	distal	5	no	22.818	22.786	PhosphoSitePlus	TCGA;ICGC;COSMIC;GDSC;CCLE	20.673	Down-regulation
TK_Src_SrcA_SRC_Y	P35968	KDR	P12931	SRC	Y224	Y224F	224	Missense	central	0	yes	20.745	0.000	EPSD	TCGA;ICGC;COSMIC	20.673	Loss
TK_Src_SrcA_SRC_Y	P35968	KDR	P12931	SRC	Y224	V218I	218	Missense	distal	-6	no	20.745	20.972	EPSD	TCGA;ICGC;COSMIC	20.673	Up-regulation
TK_Src_SrcA_SRC_Y	P35968	KDR	P12931	SRC	Y996	P992A	992	Missense	distal	-4	no	23.116	22.774	EPSD	TCGA;ICGC;COSMIC	20.673	Down-regulation
TK_Src_SrcA_SRC_Y	P35968	KDR	P12931	SRC	Y996	K997E	997	Missense	proximal	1	no	23.116	25.511	EPSD	TCGA;ICGC;COSMIC	20.673	Up-regulation
TK_Src_SrcA_SRC_Y	P35968	KDR	P12931	SRC	Y996	P992S	992	Missense	distal	-4	no	23.116	23.169	EPSD	TCGA;ICGC;COSMIC;GDSC;CCLE	20.673	Up-regulation
TK_Src_SrcA_SRC_Y	P35968	KDR	P12931	SRC	Y996	D998N	998	Missense	proximal	2	no	23.116	23.330	EPSD	TCGA;ICGC;COSMIC	20.673	Up-regulation
TK_Src_SrcA_SRC_Y	P35968	KDR	P12931	SRC	Y1054	R1051Q	1051	Missense	distal	-3	no	20.168	20.784	EPSD	TCGA;ICGC;COSMIC	20.673	Gain
TK_Src_SrcA_SRC_Y	P35968	KDR	P12931	SRC	Y1054	K1055T	1055	Missense	proximal	1	no	20.168	20.811	EPSD	TCGA;ICGC;COSMIC	20.673	Gain
TK_Src_SrcA_SRC_Y	P35968	KDR	P12931	SRC	Y1059	K1055T	1055	Missense	distal	-4	no	21.285	21.614	EPSD	TCGA;ICGC;COSMIC	20.673	Up-regulation
TK_Src_SrcA_SRC_Y	P35968	KDR	P12931	SRC	Y1059	D1052N	1052	Missense	distal	-7	no	21.285	21.205	EPSD	TCGA;ICGC;COSMIC	20.673	Down-regulation
TK_Src_SrcA_SRC_Y	P35968	KDR	P12931	SRC	Y1059	G1063E	1063	Missense	distal	4	no	21.285	21.298	EPSD	TCGA;ICGC;COSMIC	20.673	Up-regulation
TK_Src_SrcA_SRC_Y	P35968	KDR	P12931	SRC	Y1059	D1056N	1056	Missense	distal	-3	no	21.285	20.777	EPSD	TCGA;ICGC;COSMIC	20.673	Down-regulation
TK_Src_SrcA_SRC_Y	P35968	KDR	P12931	SRC	Y1059	R1066C	1066	Missense	distal	7	no	21.285	21.358	EPSD	TCGA;ICGC;COSMIC;GDSC;CCLE	20.673	Up-regulation
TK_Src_SrcA_SRC_Y	P35968	KDR	P12931	SRC	Y1059	D1058Y	1058	Missense	proximal	-1	no	21.285	22.448	EPSD	TCGA;ICGC	20.673	Up-regulation
TK_Src_SrcA_SRC_Y	P35968	KDR	P12931	SRC	Y1059	I1053M	1053	Missense	distal	-6	no	21.285	20.767	EPSD	TCGA;ICGC;COSMIC	20.673	Down-regulation
TK_Src_SrcA_SRC_Y	P35968	KDR	P12931	SRC	Y1175	A1168T	1168	Missense	distal	-7	no	20.848	21.268	PhosphoSitePlus	TCGA;ICGC;COSMIC	20.673	Up-regulation
TK_Src_SrcA_SRC_Y	P35968	KDR	P12931	SRC	Y1175	D1174Y	1174	Missense	proximal	-1	no	20.848	22.010	PhosphoSitePlus	TCGA;ICGC;COSMIC	20.673	Up-regulation
TK_Src_SrcA_SRC_Y	P35968	KDR	P12931	SRC	Y1214	H1213Y	1213	Missense	proximal	-1	no	20.456	21.052	EPSD	TCGA;ICGC;COSMIC	20.673	Gain
TK_Src_SrcA_SRC_Y	P35968	KDR	P12931	SRC	Y1309	D1315G	1315	Missense	distal	6	no	21.429	21.470	EPSD	TCGA;ICGC;COSMIC	20.673	Up-regulation
TK_Src_SrcA_SRC_Y	P35968	KDR	P12931	SRC	Y1309	G1304D	1304	Missense	distal	-5	no	21.429	21.581	EPSD	TCGA;ICGC;COSMIC	20.673	Up-regulation
TK_Src_SrcA_SRC_Y	P35968	KDR	P12931	SRC	Y1309	D1312N	1312	Missense	distal	3	no	21.429	22.505	EPSD	TCGA;ICGC;COSMIC;GDSC;CCLE	20.673	Up-regulation
TK_Src_SrcA_SRC_Y	P35968	KDR	P12931	SRC	Y1309	G1304S	1304	Missense	distal	-5	no	21.429	21.497	EPSD	TCGA;ICGC;COSMIC	20.673	Up-regulation
TK_Src_SrcA_SRC_Y	P35968	KDR	P12931	SRC	Y1319	L1326F	1326	Missense	distal	7	no	21.524	21.539	EPSD	TCGA;ICGC;COSMIC	20.673	Up-regulation
TK_Src_SrcA_SRC_Y	P35968	KDR	P12931	SRC	Y1319	D1315G	1315	Missense	distal	-4	no	21.524	20.865	EPSD	TCGA;ICGC;COSMIC	20.673	Down-regulation
TK_Src_SrcA_SRC_Y	P35968	KDR	P12931	SRC	Y1319	D1312N	1312	Missense	distal	-7	no	21.524	21.444	EPSD	TCGA;ICGC;COSMIC;GDSC;CCLE	20.673	Down-regulation
TK_Src_SrcA_SRC_Y	P35968	KDR	P12931	SRC	Y1319	Y1319C	1319	Missense	central	0	yes	21.524	0.000	EPSD	TCGA;ICGC;COSMIC	20.673	Loss
TK_Src_SrcA_SRC_Y	P51813	BMX	P12931	SRC	Y40	E42K	42	Missense	proximal	2	no	21.486	20.316	EPSD	TCGA;ICGC;COSMIC	20.673	Loss
TK_Src_SrcA_SRC_Y	P51813	BMX	P12931	SRC	Y216	Y216H	216	Missense	central	0	yes	20.832	0.000	EPSD	TCGA;ICGC;COSMIC	20.673	Loss
TK_Src_SrcA_SRC_Y	P51813	BMX	P12931	SRC	Y566	D563H	563	Missense	distal	-3	no	25.486	23.909	PhosphoSitePlus	TCGA;ICGC;COSMIC	20.673	Down-regulation
TK_Src_SrcA_SRC_Y	P51813	BMX	P12931	SRC	Y566	L562I	562	Missense	distal	-4	no	25.486	25.048	PhosphoSitePlus	TCGA;ICGC;COSMIC	20.673	Down-regulation
TK_Src_SrcA_SRC_Y	P14923	JUP	P12931	SRC	Y22	E15K	15	Missense	distal	-7	no	21.760	21.596	EPSD	TCGA;ICGC;COSMIC	20.673	Down-regulation
TK_Src_SrcA_SRC_Y	P14923	JUP	P12931	SRC	Y22	D23N	23	Missense	proximal	1	no	21.760	20.368	EPSD	TCGA;ICGC;COSMIC	20.673	Loss
TK_Src_SrcA_SRC_Y	P14923	JUP	P12931	SRC	Y22	G29S	29	Missense	distal	7	no	21.760	21.729	EPSD	TCGA;ICGC;COSMIC	20.673	Down-regulation
TK_Src_SrcA_SRC_Y	P14923	JUP	P12931	SRC	Y324	I318M	318	Missense	distal	-6	no	23.020	22.502	EPSD	TCGA;ICGC;COSMIC	20.673	Down-regulation
TK_Src_SrcA_SRC_Y	P14923	JUP	P12931	SRC	Y324	E325K	325	Missense	proximal	1	no	23.020	20.626	EPSD	TCGA;ICGC;COSMIC	20.673	Loss
TK_Src_SrcA_SRC_Y	P14923	JUP	P12931	SRC	Y324	R320H	320	Missense	distal	-4	no	23.020	22.536	EPSD	TCGA;ICGC;COSMIC	20.673	Down-regulation
TK_Src_SrcA_SRC_Y	P14923	JUP	P12931	SRC	Y644	R651C	651	Missense	distal	7	no	20.870	20.943	PhosphoSitePlus	TCGA	20.673	Up-regulation
TK_Src_SrcA_SRC_Y	P14923	JUP	P12931	SRC	Y644	A645T	645	Missense	proximal	1	no	20.870	20.416	PhosphoSitePlus	TCGA;ICGC;COSMIC	20.673	Loss
TK_Src_SrcA_SRC_Y	Q8WWM7	ATXN2L	P12931	SRC	Y145	G147S	147	Missense	proximal	2	no	21.256	22.384	EPSD	TCGA;ICGC;COSMIC	20.673	Up-regulation
TK_Src_SrcA_SRC_Y	Q8WWM7	ATXN2L	P12931	SRC	Y145	F149L	149	Missense	distal	4	no	21.256	21.274	EPSD	TCGA;ICGC;COSMIC	20.673	Up-regulation
TK_Src_SrcA_SRC_Y	Q8WWM7	ATXN2L	P12931	SRC	Y241	D240N	240	Missense	proximal	-1	no	21.503	20.553	EPSD	TCGA;ICGC;COSMIC	20.673	Loss
TK_Src_SrcA_SRC_Y	Q8WWM7	ATXN2L	P12931	SRC	Y264	N263H	263	Missense	proximal	-1	no	20.154	21.671	EPSD	TCGA;ICGC;COSMIC	20.673	Gain
TK_Src_SrcA_SRC_Y	Q8WWM7	ATXN2L	P12931	SRC	Y349	Y349C	349	Missense	central	0	yes	20.848	0.000	EPSD	TCGA;ICGC;COSMIC	20.673	Loss
TK_Src_SrcA_SRC_Y	Q13017	ARHGAP5	P12931	SRC	Y306	P301S	301	Missense	distal	-5	no	21.741	21.843	EPSD	TCGA;ICGC;COSMIC	20.673	Up-regulation
TK_Src_SrcA_SRC_Y	Q13017	ARHGAP5	P12931	SRC	Y306	H300Y	300	Missense	distal	-6	no	21.741	21.911	EPSD	TCGA;ICGC;COSMIC	20.673	Up-regulation
TK_Src_SrcA_SRC_Y	Q13017	ARHGAP5	P12931	SRC	Y306	P301H	301	Missense	distal	-5	no	21.741	21.969	EPSD	TCGA;ICGC;COSMIC	20.673	Up-regulation
TK_Src_SrcA_SRC_Y	Q13017	ARHGAP5	P12931	SRC	Y630	R635Q	635	Missense	distal	5	no	24.121	24.146	EPSD	TCGA;ICGC;COSMIC	20.673	Up-regulation
TK_Src_SrcA_SRC_Y	Q13017	ARHGAP5	P12931	SRC	Y630	P636S	636	Missense	distal	6	no	24.121	24.105	EPSD	TCGA;ICGC	20.673	Down-regulation
TK_Src_SrcA_SRC_Y	Q13017	ARHGAP5	P12931	SRC	Y991	P989S	989	Missense	proximal	-2	no	21.393	20.607	EPSD	TCGA;ICGC;COSMIC	20.673	Loss
TK_Src_SrcA_SRC_Y	Q13017	ARHGAP5	P12931	SRC	Y991	I994F	994	Missense	distal	3	no	21.393	21.720	EPSD	TCGA;ICGC;COSMIC	20.673	Up-regulation
TK_Src_SrcA_SRC_Y	Q13017	ARHGAP5	P12931	SRC	Y1109	D1106H	1106	Missense	distal	-3	no	23.618	22.041	PhosphoSitePlus	TCGA;ICGC;COSMIC	20.673	Down-regulation
TK_Src_SrcA_SRC_Y	P49023	PXN	P12931	SRC	Y31	E27G	27	Missense	distal	-4	no	23.146	22.713	EPSD	TCGA	20.673	Down-regulation
TK_Src_SrcA_SRC_Y	P49023	PXN	P12931	SRC	Y118	Q124H	124	Missense	distal	6	no	23.383	23.395	EPSD	TCGA;COSMIC	20.673	Up-regulation
TK_Src_SrcA_SRC_Y	P49023	PXN	P12931	SRC	Y181	S188N	188	Missense	distal	7	no	22.194	22.161	EPSD	TCGA	20.673	Down-regulation
TK_Src_SrcA_SRC_Y	P12956	XRCC6	P12931	SRC	Y322	T316I	316	Missense	distal	-6	no	21.247	21.277	EPSD	TCGA;ICGC;COSMIC	20.673	Up-regulation
TK_Src_SrcA_SRC_Y	P12956	XRCC6	P12931	SRC	Y322	D315N	315	Missense	distal	-7	no	21.247	21.167	EPSD	TCGA;ICGC;COSMIC	20.673	Down-regulation
TK_Src_SrcA_SRC_Y	Q6UN15	FIP1L1	P12931	SRC	Y110	A107S	107	Missense	distal	-3	no	21.781	22.686	PhosphoSitePlus	TCGA;ICGC	20.673	Up-regulation
TK_Src_SrcA_SRC_Y	Q6UN15	FIP1L1	P12931	SRC	Y110	T105M	105	Missense	distal	-5	no	21.781	21.674	PhosphoSitePlus	TCGA;ICGC;COSMIC	20.673	Down-regulation
TK_Src_SrcA_SRC_Y	Q6UN15	FIP1L1	P12931	SRC	Y129	G126E	126	Missense	distal	-3	no	21.466	22.069	EPSD	TCGA;ICGC;COSMIC	20.673	Up-regulation
TK_Src_SrcA_SRC_Y	Q6UN15	FIP1L1	P12931	SRC	Y129	T124I	124	Missense	distal	-5	no	21.466	21.469	EPSD	TCGA;ICGC;COSMIC	20.673	Up-regulation
TK_Src_SrcA_SRC_Y	Q6UN15	FIP1L1	P12931	SRC	Y426	S420C	420	Missense	distal	-6	no	21.351	20.814	EPSD	TCGA;ICGC;COSMIC	20.673	Down-regulation
TK_Src_SrcA_SRC_Y	Q6UN15	FIP1L1	P12931	SRC	Y426	P425S	425	Missense	proximal	-1	no	21.351	21.000	EPSD	TCGA;ICGC;COSMIC	20.673	Down-regulation
TK_Src_SrcA_SRC_Y	Q6UN15	FIP1L1	P12931	SRC	Y426	R422H	422	Missense	distal	-4	no	21.351	20.867	EPSD	TCGA;ICGC;COSMIC	20.673	Down-regulation
TK_Src_SrcA_SRC_Y	Q6UN15	FIP1L1	P12931	SRC	Y426	R419C	419	Missense	distal	-7	no	21.351	20.210	EPSD	TCGA;ICGC;COSMIC	20.673	Loss
TK_Src_SrcA_SRC_Y	Q6UN15	FIP1L1	P12931	SRC	Y505	D501A	501	Missense	distal	-4	no	21.632	20.290	EPSD	TCGA;ICGC;COSMIC	20.673	Loss
TK_Src_SrcA_SRC_Y	Q6UN15	FIP1L1	P12931	SRC	Y505	R504Q	504	Missense	proximal	-1	no	21.632	23.464	EPSD	TCGA;ICGC	20.673	Up-regulation
TK_Src_SrcA_SRC_Y	Q6UN15	FIP1L1	P12931	SRC	Y505	E512D	512	Missense	distal	7	no	21.632	21.593	EPSD	TCGA;ICGC;COSMIC	20.673	Down-regulation
TK_Src_SrcA_SRC_Y	P08727	KRT19	P12931	SRC	Y256	R253L	253	Missense	distal	-3	no	20.885	19.691	EPSD	TCGA;ICGC;COSMIC	20.673	Loss
TK_Src_SrcA_SRC_Y	P08727	KRT19	P12931	SRC	Y256	D251G	251	Missense	distal	-5	no	20.885	20.733	EPSD	TCGA;ICGC;COSMIC	20.673	Down-regulation
TK_Src_SrcA_SRC_Y	P08727	KRT19	P12931	SRC	Y391	H390Y	390	Missense	proximal	-1	no	22.099	22.695	PhosphoSitePlus	TCGA;ICGC;COSMIC	20.673	Up-regulation
TK_Src_SrcA_SRC_Y	P08727	KRT19	P12931	SRC	Y391	E385K	385	Missense	distal	-6	no	22.099	22.087	PhosphoSitePlus	TCGA;ICGC;COSMIC	20.673	Down-regulation
TK_Src_SrcA_SRC_Y	P08727	KRT19	P12931	SRC	Y391	E388G	388	Missense	distal	-3	no	22.099	21.496	PhosphoSitePlus	TCGA;ICGC;COSMIC	20.673	Down-regulation
TK_Src_SrcA_SRC_Y	Q14721	KCNB1	P12931	SRC	Y128	C133Y	133	Missense	distal	5	no	21.700	21.655	PhosphoSitePlus	TCGA;ICGC;COSMIC	20.673	Down-regulation
TK_Src_SrcA_SRC_Y	Q14721	KCNB1	P12931	SRC	Y128	D125N	125	Missense	distal	-3	no	21.700	21.192	PhosphoSitePlus	TCGA;ICGC;COSMIC	20.673	Down-regulation
TK_Src_SrcA_SRC_Y	Q14721	KCNB1	P12931	SRC	Y726	S723Y	723	Missense	distal	-3	no	21.536	20.615	EPSD	TCGA;ICGC;COSMIC	20.673	Loss
TK_Src_SrcA_SRC_Y	Q14721	KCNB1	P12931	SRC	Y726	P721T	721	Missense	distal	-5	no	21.536	21.329	EPSD	TCGA;ICGC;COSMIC	20.673	Down-regulation
TK_Src_SrcA_SRC_Y	Q14721	KCNB1	P12931	SRC	Y726	K732N	732	Missense	distal	6	no	21.536	21.491	EPSD	TCGA;ICGC	20.673	Down-regulation
TK_Src_SrcA_SRC_Y	O15259	NPHP1	P12931	SRC	Y46	C49Y	49	Missense	distal	3	no	21.083	22.158	EPSD	TCGA;ICGC	20.673	Up-regulation
TK_Src_SrcA_SRC_Y	O15259	NPHP1	P12931	SRC	Y46	R48I	48	Missense	proximal	2	no	21.083	20.577	EPSD	TCGA;ICGC;COSMIC	20.673	Loss
TK_Src_SrcA_SRC_Y	O15259	NPHP1	P12931	SRC	Y46	N40D	40	Missense	distal	-6	no	21.083	21.273	EPSD	TCGA;ICGC	20.673	Up-regulation
TK_Src_SrcA_SRC_Y	O15259	NPHP1	P12931	SRC	Y46	R42I	42	Missense	distal	-4	no	21.083	19.687	EPSD	TCGA;ICGC;COSMIC	20.673	Loss
TK_Src_SrcA_SRC_Y	Q9UN19	DAPP1	P12931	SRC	Y139	S141F	141	Missense	proximal	2	no	23.548	22.128	PhosphoSitePlus	TCGA;ICGC;COSMIC	20.673	Down-regulation
TK_Src_SrcA_SRC_Y	Q9UN19	DAPP1	P12931	SRC	Y139	V144A	144	Missense	distal	5	no	23.548	23.407	PhosphoSitePlus	TCGA;ICGC;COSMIC	20.673	Down-regulation
TK_Src_SrcA_SRC_Y	Q9UN19	DAPP1	P12931	SRC	Y139	E135K	135	Missense	distal	-4	no	23.548	22.378	PhosphoSitePlus	TCGA;ICGC;COSMIC	20.673	Down-regulation
TK_Src_SrcA_SRC_Y	Q9UN19	DAPP1	P12931	SRC	Y139	S141Y	141	Missense	proximal	2	no	23.548	23.107	PhosphoSitePlus	TCGA;ICGC;COSMIC	20.673	Down-regulation
TK_Src_SrcA_SRC_Y	P11511	CYP19A1	P12931	SRC	Y184	S182L	182	Missense	proximal	-2	no	23.226	22.482	EPSD	TCGA;ICGC;COSMIC;GDSC;CCLE	20.673	Down-regulation
TK_Src_SrcA_SRC_Y	P11511	CYP19A1	P12931	SRC	Y184	N180K	180	Missense	distal	-4	no	23.226	22.363	EPSD	TCGA;ICGC;COSMIC	20.673	Down-regulation
TK_Src_SrcA_SRC_Y	P11511	CYP19A1	P12931	SRC	Y184	E181K	181	Missense	distal	-3	no	23.226	21.515	EPSD	TCGA;ICGC;COSMIC	20.673	Down-regulation
TK_Src_SrcA_SRC_Y	P11511	CYP19A1	P12931	SRC	Y361	E357K	357	Missense	distal	-4	no	22.879	21.709	PhosphoSitePlus	TCGA;ICGC;COSMIC	20.673	Down-regulation
TK_Src_SrcA_SRC_Y	P11511	CYP19A1	P12931	SRC	Y361	R365W	365	Missense	distal	4	no	22.879	22.851	PhosphoSitePlus	TCGA;ICGC;COSMIC	20.673	Down-regulation
TK_Src_SrcA_SRC_Y	P98161	PKD1	P12931	SRC	Y2336	V2334M	2334	Missense	proximal	-2	no	21.526	20.855	EPSD	TCGA;ICGC;COSMIC	20.673	Down-regulation
TK_Src_SrcA_SRC_Y	P98161	PKD1	P12931	SRC	Y4237	E4234K	4234	Missense	distal	-3	no	23.643	21.931	PhosphoSitePlus	TCGA;COSMIC	20.673	Down-regulation
TK_Src_SrcA_SRC_Y	P10636	MAPT	P12931	SRC	Y18	D13N	13	Missense	distal	-5	no	21.842	21.630	PhosphoSitePlus	TCGA;ICGC;COSMIC	20.673	Down-regulation
TK_Src_SrcA_SRC_Y	P10636	MAPT	P12931	SRC	Y18	R23S	23	Missense	distal	5	no	21.842	21.818	PhosphoSitePlus	TCGA;ICGC;COSMIC	20.673	Down-regulation
TK_Src_SrcA_SRC_Y	P10636	MAPT	P12931	SRC	Y18	H14Y	14	Missense	distal	-4	no	21.842	22.010	PhosphoSitePlus	TCGA;ICGC;COSMIC	20.673	Up-regulation
TK_Src_SrcA_SRC_Y	P10636	MAPT	P12931	SRC	Y18	G21W	21	Missense	distal	3	no	21.842	20.461	PhosphoSitePlus	TCGA;ICGC;COSMIC	20.673	Loss
TK_Src_SrcA_SRC_Y	P10636	MAPT	P12931	SRC	Y18	K24I	24	Missense	distal	6	no	21.842	21.835	PhosphoSitePlus	TCGA;ICGC	20.673	Down-regulation
TK_Src_SrcA_SRC_Y	P42224	STAT1	P12931	SRC	Y68	R70H	70	Missense	proximal	2	no	22.217	22.064	EPSD	TCGA;ICGC;COSMIC	20.673	Down-regulation
TK_Src_SrcA_SRC_Y	P42224	STAT1	P12931	SRC	Y68	Q67K	67	Missense	proximal	-1	no	22.217	20.714	EPSD	TCGA	20.673	Down-regulation
TK_Src_SrcA_SRC_Y	P42224	STAT1	P12931	SRC	Y68	R70C	70	Missense	proximal	2	no	22.217	21.616	EPSD	TCGA;ICGC;COSMIC	20.673	Down-regulation
TK_Src_SrcA_SRC_Y	P42224	STAT1	P12931	SRC	Y68	S72Y	72	Missense	distal	4	no	22.217	22.182	EPSD	TCGA;ICGC;COSMIC	20.673	Down-regulation
TK_Src_SrcA_SRC_Y	Q9NR80	ARHGEF4	P12931	SRC	Y165	Y165F	165	Missense	central	0	yes	23.635	0.000	EPSD	TCGA;ICGC;COSMIC	20.673	Loss
TK_Src_SrcA_SRC_Y	Q9NR80	ARHGEF4	P12931	SRC	Y165	V158A	158	Missense	distal	-7	no	23.635	23.583	EPSD	TCGA;ICGC;COSMIC	20.673	Down-regulation
TK_Src_SrcA_SRC_Y	Q9NR80	ARHGEF4	P12931	SRC	Y175	G179V	179	Missense	distal	4	no	22.527	22.523	EPSD	TCGA;ICGC;COSMIC	20.673	Down-regulation
TK_Src_SrcA_SRC_Y	Q9NR80	ARHGEF4	P12931	SRC	Y175	H174Y	174	Missense	proximal	-1	no	22.527	23.122	EPSD	TCGA;ICGC;COSMIC	20.673	Up-regulation
TK_Src_SrcA_SRC_Y	Q9NR80	ARHGEF4	P12931	SRC	Y175	P178S	178	Missense	distal	3	no	22.527	21.788	EPSD	TCGA;ICGC	20.673	Down-regulation
TK_Src_SrcA_SRC_Y	P50281	MMP14	P12931	SRC	Y138	T132S	132	Missense	distal	-6	no	22.285	22.337	EPSD	TCGA;ICGC;COSMIC	20.673	Up-regulation
TK_Src_SrcA_SRC_Y	O43613	HCRTR1	P12931	SRC	Y27	Y34C	34	Missense	distal	7	no	21.876	22.000	EPSD	TCGA	20.673	Up-regulation
TK_Src_SrcA_SRC_Y	O43613	HCRTR1	P12931	SRC	Y27	Y27N	27	Missense	central	0	yes	21.876	0.000	EPSD	TCGA;ICGC;COSMIC	20.673	Loss
TK_Src_SrcA_SRC_Y	P12235	SLC25A4	P12931	SRC	Y174	V179I	179	Missense	distal	5	no	20.732	20.782	EPSD	TCGA;ICGC;COSMIC	20.673	Up-regulation
CMGC_CDK_CDK2_CDK3_ST	Q5TKA1	LIN9	Q00526	CDK3	S58	K59N	59	Missense	proximal	1	no	5.800	3.914	EPSD	TCGA;COSMIC	5.767	Loss
CMGC_CDK_CDK2_CDK3_ST	Q14934	NFATC4	Q00526	CDK3	S120	P114H	114	Missense	distal	-6	no	7.684	8.155	EPSD	TCGA	5.767	Up-regulation
CMGC_CDK_CDK2_CDK3_ST	Q14934	NFATC4	Q00526	CDK3	S819	G824V	824	Missense	distal	5	no	8.863	8.606	EPSD	TCGA;COSMIC	5.767	Down-regulation
CMGC_CDK_CDK2_CDK3_ST	P03372	ESR1	Q00526	CDK3	S46	Y52H	52	Missense	distal	6	no	6.525	6.515	EPSD	TCGA;ICGC;COSMIC	5.767	Down-regulation
CMGC_CDK_CDK2_CDK3_ST	P03372	ESR1	Q00526	CDK3	S46	E41D	41	Missense	distal	-5	no	6.525	6.120	EPSD	TCGA;ICGC;COSMIC	5.767	Down-regulation
CMGC_CDK_CDK2_CDK3_ST	P03372	ESR1	Q00526	CDK3	S46	G40V	40	Missense	distal	-6	no	6.525	5.940	EPSD	TCGA;ICGC;COSMIC	5.767	Down-regulation
CMGC_CDK_CDK2_CDK3_ST	P03372	ESR1	Q00526	CDK3	S106	P113S	113	Missense	distal	7	no	13.716	13.765	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	5.767	Up-regulation
CMGC_CDK_CDK2_CDK3_ST	P03372	ESR1	Q00526	CDK3	S118	P113S	113	Missense	distal	-5	no	13.277	12.711	PhosphoSitePlus;EPSD	TCGA;ICGC;COSMIC	5.767	Down-regulation
CMGC_CDK_CDK2_CDK3_ST	P03372	ESR1	Q00526	CDK3	S294	W292R	292	Missense	proximal	-2	no	9.470	9.626	EPSD	TCGA;ICGC;COSMIC	5.767	Up-regulation
CMGC_CDK_CDK2_CDK3_ST	P03372	ESR1	Q00526	CDK3	S294	I298M	298	Missense	distal	4	no	9.470	9.541	EPSD	TCGA;ICGC;COSMIC	5.767	Up-regulation
CMGC_CDK_CDK2_CDK3_ST	P03372	ESR1	Q00526	CDK3	S294	L291I	291	Missense	distal	-3	no	9.470	9.469	EPSD	TCGA;ICGC;COSMIC	5.767	Down-regulation
CMGC_CDK_CDK2_CDK3_ST	P46531	NOTCH1	Q00526	CDK3	T535	K538N	538	Missense	distal	3	no	10.243	9.015	EPSD	TCGA;ICGC;COSMIC	5.767	Down-regulation
CMGC_CDK_CDK2_CDK3_ST	P46531	NOTCH1	Q00526	CDK3	T535	C532Y	532	Missense	distal	-3	no	10.243	10.212	EPSD	TCGA	5.767	Down-regulation
CMGC_CDK_CDK2_CDK3_ST	P46531	NOTCH1	Q00526	CDK3	T535	A541V	541	Missense	distal	6	no	10.243	10.226	EPSD	TCGA;ICGC;COSMIC	5.767	Down-regulation
CMGC_CDK_CDK2_CDK3_ST	P46531	NOTCH1	Q00526	CDK3	T1861	S1856F	1856	Missense	distal	-5	no	6.686	7.525	EPSD	TCGA;ICGC;COSMIC	5.767	Up-regulation
CMGC_CDK_CDK2_CDK3_ST	P46531	NOTCH1	Q00526	CDK3	T1861	R1854H	1854	Missense	distal	-7	no	6.686	6.465	EPSD	TCGA;ICGC;COSMIC;GDSC;CCLE	5.767	Down-regulation
CMGC_CDK_CDK2_CDK3_ST	P46531	NOTCH1	Q00526	CDK3	T1861	P1862L	1862	Missense	proximal	1	no	6.686	-0.058	EPSD	TCGA;ICGC;COSMIC	5.767	Loss
CMGC_CDK_CDK2_CDK3_ST	P46531	NOTCH1	Q00526	CDK3	S1941	R1940H	1940	Missense	proximal	-1	no	6.027	6.021	EPSD	TCGA;ICGC;COSMIC	5.767	Down-regulation
CMGC_CDK_CDK2_CDK3_ST	P46531	NOTCH1	Q00526	CDK3	S1941	R1946H	1946	Missense	distal	5	no	6.027	5.920	EPSD	TCGA;ICGC;COSMIC	5.767	Down-regulation
CMGC_CDK_CDK2_CDK3_ST	P46531	NOTCH1	Q00526	CDK3	S1941	D1942V	1942	Missense	proximal	1	no	6.027	6.126	EPSD	TCGA;ICGC;COSMIC	5.767	Up-regulation
CMGC_CDK_CDK2_CDK3_ST	P46531	NOTCH1	Q00526	CDK3	S1941	R1937H	1937	Missense	distal	-4	no	6.027	6.406	EPSD	TCGA;ICGC;COSMIC	5.767	Up-regulation
CMGC_CDK_CDK2_CDK3_ST	P46531	NOTCH1	Q00526	CDK3	S1941	A1936T	1936	Missense	distal	-5	no	6.027	6.194	EPSD	TCGA;ICGC;COSMIC	5.767	Up-regulation
CMGC_CDK_CDK2_CDK3_ST	P46531	NOTCH1	Q00526	CDK3	S1941	L1934M	1934	Missense	distal	-7	no	6.027	5.857	EPSD	TCGA;ICGC;COSMIC	5.767	Down-regulation
CMGC_CDK_CDK2_CDK3_ST	P46531	NOTCH1	Q00526	CDK3	T1986	R1982W	1982	Missense	distal	-4	no	6.356	6.894	EPSD	TCGA;ICGC;COSMIC	5.767	Up-regulation
CMGC_CDK_CDK2_CDK3_ST	P46531	NOTCH1	Q00526	CDK3	T1986	H1993Y	1993	Missense	distal	7	no	6.356	6.367	EPSD	TCGA;ICGC	5.767	Up-regulation
CMGC_CDK_CDK2_CDK3_ST	P46531	NOTCH1	Q00526	CDK3	T1986	L1980P	1980	Missense	distal	-6	no	6.356	5.361	EPSD	TCGA;ICGC;COSMIC	5.767	Loss
CMGC_CDK_CDK2_CDK3_ST	P46531	NOTCH1	Q00526	CDK3	T1997	T1996M	1996	Missense	proximal	-1	no	7.292	7.296	EPSD	TCGA;ICGC;COSMIC;GDSC;CCLE	5.767	Up-regulation
CMGC_CDK_CDK2_CDK3_ST	P46531	NOTCH1	Q00526	CDK3	T1997	H1993Y	1993	Missense	distal	-4	no	7.292	7.415	EPSD	TCGA;ICGC	5.767	Up-regulation
CMGC_CDK_CDK2_CDK3_ST	P46531	NOTCH1	Q00526	CDK3	T1997	T1997M	1997	Missense	central	0	yes	7.292	0.000	EPSD	TCGA;ICGC;COSMIC	5.767	Loss
CMGC_CDK_CDK2_CDK3_ST	P46531	NOTCH1	Q00526	CDK3	S2121	V2119M	2119	Missense	proximal	-2	no	9.030	9.195	EPSD	TCGA;ICGC;COSMIC	5.767	Up-regulation
CMGC_CDK_CDK2_CDK3_ST	P46531	NOTCH1	Q00526	CDK3	S2163	S2163I	2163	Missense	central	0	yes	6.163	0.000	EPSD	TCGA;ICGC;COSMIC	5.767	Loss
CMGC_CDK_CDK2_CDK3_ST	P46531	NOTCH1	Q00526	CDK3	S2163	R2159C	2159	Missense	distal	-4	no	6.163	6.695	EPSD	TCGA;ICGC;COSMIC	5.767	Up-regulation
CMGC_CDK_CDK2_CDK3_ST	P46531	NOTCH1	Q00526	CDK3	S2215	V2213L	2213	Missense	proximal	-2	no	10.376	10.599	EPSD	TCGA;ICGC;COSMIC	5.767	Up-regulation
CMGC_CDK_CDK2_CDK3_ST	P46531	NOTCH1	Q00526	CDK3	S2215	P2222L	2222	Missense	distal	7	no	10.376	10.450	EPSD	TCGA;ICGC;COSMIC;CCLE	5.767	Up-regulation
CMGC_CDK_CDK2_CDK3_ST	P46531	NOTCH1	Q00526	CDK3	S2215	P2222S	2222	Missense	distal	7	no	10.376	10.425	EPSD	TCGA;ICGC;COSMIC	5.767	Up-regulation
CMGC_CDK_CDK2_CDK3_ST	P46531	NOTCH1	Q00526	CDK3	S2221	P2222L	2222	Missense	proximal	1	no	11.378	4.633	EPSD	TCGA;ICGC;COSMIC;CCLE	5.767	Loss
CMGC_CDK_CDK2_CDK3_ST	P46531	NOTCH1	Q00526	CDK3	S2221	P2222S	2222	Missense	proximal	1	no	11.378	6.314	EPSD	TCGA;ICGC;COSMIC	5.767	Down-regulation
CMGC_CDK_CDK2_CDK3_ST	P46531	NOTCH1	Q00526	CDK3	S2221	P2227S	2227	Missense	distal	6	no	11.378	11.342	EPSD	TCGA;ICGC;COSMIC	5.767	Down-regulation
CMGC_CDK_CDK2_CDK3_ST	P46531	NOTCH1	Q00526	CDK3	T2511	P2514T	2514	Missense	distal	3	no	14.773	12.299	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	5.767	Down-regulation
CMGC_CDK_CDK2_CDK3_ST	P46531	NOTCH1	Q00526	CDK3	S2513	P2514T	2514	Missense	proximal	1	no	10.776	4.572	PhosphoSitePlus;EPSD	TCGA;ICGC;COSMIC	5.767	Loss
CMGC_CDK_CDK2_CDK3_ST	P46531	NOTCH1	Q00526	CDK3	S2516	S2521F	2521	Missense	distal	5	no	12.861	13.177	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	5.767	Up-regulation
CMGC_CDK_CDK2_CDK3_ST	P46531	NOTCH1	Q00526	CDK3	S2516	S2523L	2523	Missense	distal	7	no	12.861	12.885	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC;GDSC;CCLE	5.767	Up-regulation
CMGC_CDK_CDK2_CDK3_ST	P46531	NOTCH1	Q00526	CDK3	S2516	P2514T	2514	Missense	proximal	-2	no	12.861	12.929	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	5.767	Up-regulation
CMGC_CDK_CDK2_CDK3_ST	P46531	NOTCH1	Q00526	CDK3	S2524	S2521F	2521	Missense	distal	-3	no	5.655	5.769	EPSD	TCGA;ICGC;COSMIC	5.767	Gain
CMGC_CDK_CDK2_CDK3_ST	P05412	JUN	Q00526	CDK3	S73	S73L	73	Missense	central	0	yes	13.846	0.000	PhosphoSitePlus;EPSD	TCGA;ICGC;COSMIC	5.767	Loss
CMGC_CDK_CDK2_CDK3_ST	P05412	JUN	Q00526	CDK3	T91	G86W	86	Missense	distal	-5	no	8.463	8.326	EPSD	TCGA;ICGC;COSMIC	5.767	Down-regulation
CMGC_CDK_CDK2_CDK3_ST	P05412	JUN	Q00526	CDK3	T93	G86W	86	Missense	distal	-7	no	8.816	8.679	EPSD	TCGA;ICGC;COSMIC	5.767	Down-regulation
CMGC_CDK_CDK2_CDK3_ST	P05412	JUN	Q00526	CDK3	T93	C99Y	99	Missense	distal	6	no	8.816	8.830	EPSD	TCGA;ICGC;COSMIC	5.767	Up-regulation
CMGC_CDK_CDK2_CDK3_ST	P05412	JUN	Q00526	CDK3	S243	P244L	244	Missense	proximal	1	no	6.622	-0.123	EPSD	TCGA;ICGC;COSMIC	5.767	Loss
CMGC_CDK_CDK2_CDK3_ST	P18846	ATF1	Q00526	CDK3	S50	D46N	46	Missense	distal	-4	no	7.244	7.689	EPSD	TCGA;ICGC;COSMIC	5.767	Up-regulation
CMGC_CDK_CDK2_CDK3_ST	P18846	ATF1	Q00526	CDK3	S50	S47T	47	Missense	distal	-3	no	7.244	7.336	EPSD	TCGA;ICGC;COSMIC	5.767	Up-regulation
CMGC_CDK_CDK2_CDK3_ST	P18846	ATF1	Q00526	CDK3	S72	T76I	76	Missense	distal	4	no	7.813	7.719	EPSD	TCGA;ICGC	5.767	Down-regulation
CMGC_CDK_CDK2_CDK3_ST	P18846	ATF1	Q00526	CDK3	T184	Q180H	180	Missense	distal	-4	no	9.924	9.509	EPSD	TCGA;COSMIC	5.767	Down-regulation
CMGC_CDK_CDK2_CDK3_ST	P18846	ATF1	Q00526	CDK3	T184	R182Q	182	Missense	proximal	-2	no	9.924	9.768	EPSD	TCGA;COSMIC	5.767	Down-regulation
CMGC_CDK_CDK2_CDK3_ST	Q12800	TFCP2	Q00526	CDK3	S54	E53K	53	Missense	proximal	-1	no	6.933	6.929	EPSD	TCGA;ICGC;COSMIC	5.767	Down-regulation
CMGC_CDK_CDK2_CDK3_ST	Q12800	TFCP2	Q00526	CDK3	S54	I48V	48	Missense	distal	-6	no	6.933	6.300	EPSD	TCGA;ICGC	5.767	Down-regulation
CMGC_CDK_CDK2_CDK3_ST	Q12800	TFCP2	Q00526	CDK3	T258	R257Q	257	Missense	proximal	-1	no	9.058	9.047	EPSD	TCGA;ICGC;COSMIC	5.767	Down-regulation
CMGC_CDK_CDK2_CDK3_ST	Q12800	TFCP2	Q00526	CDK3	S289	P290Q	290	Missense	proximal	1	no	10.601	4.715	EPSD	TCGA;ICGC;COSMIC	5.767	Loss
CMGC_CDK_CDK2_CDK3_ST	Q12800	TFCP2	Q00526	CDK3	S289	Y285F	285	Missense	distal	-4	no	10.601	10.451	EPSD	TCGA;ICGC;COSMIC	5.767	Down-regulation
CMGC_CDK_CDK2_CDK3_ST	Q12800	TFCP2	Q00526	CDK3	S289	E282K	282	Missense	distal	-7	no	10.601	10.505	EPSD	TCGA;COSMIC	5.767	Down-regulation
CMGC_CDK_CDK2_CDK3_ST	Q12800	TFCP2	Q00526	CDK3	S291	P290Q	290	Missense	proximal	-1	no	8.309	8.312	EPSD	TCGA;ICGC;COSMIC	5.767	Up-regulation
CMGC_CDK_CDK2_CDK3_ST	Q12800	TFCP2	Q00526	CDK3	S291	Y285F	285	Missense	distal	-6	no	8.309	8.539	EPSD	TCGA;ICGC;COSMIC	5.767	Up-regulation
CMGC_CDK_CDK2_CDK3_ST	Q12800	TFCP2	Q00526	CDK3	S309	E315Q	315	Missense	distal	6	no	14.086	14.091	PhosphoSitePlus	TCGA;COSMIC	5.767	Up-regulation
CMGC_CDK_CDK2_CDK3_ST	Q8TDN4	CABLES1	Q00526	CDK3	S168	L170M	170	Missense	proximal	2	no	5.803	5.933	EPSD	TCGA;ICGC;COSMIC	5.767	Up-regulation
CMGC_CDK_CDK2_CDK3_ST	Q8TDN4	CABLES1	Q00526	CDK3	S257	A251V	251	Missense	distal	-6	no	7.462	7.417	EPSD	TCGA;ICGC;COSMIC	5.767	Down-regulation
CMGC_CDK_CDK2_CDK3_ST	Q8TDN4	CABLES1	Q00526	CDK3	S287	R283W	283	Missense	distal	-4	no	5.446	5.984	EPSD	TCGA;COSMIC	5.767	Gain
CMGC_CDK_CDK2_CDK3_ST	Q8TDN4	CABLES1	Q00526	CDK3	S287	R283Q	283	Missense	distal	-4	no	5.446	6.240	EPSD	TCGA;COSMIC	5.767	Gain
CMGC_CDK_CDK2_CDK3_ST	Q8TDN4	CABLES1	Q00526	CDK3	S291	S290F	290	Missense	proximal	-1	no	6.075	6.091	EPSD	TCGA;COSMIC	5.767	Up-regulation
CMGC_CDK_CDK2_CDK3_ST	Q8TDN4	CABLES1	Q00526	CDK3	S313	K317N	317	Missense	distal	4	no	15.982	15.995	PhosphoSitePlus	TCGA;COSMIC	5.767	Up-regulation
CMGC_CDK_CDK2_CDK3_ST	Q8TDN4	CABLES1	Q00526	CDK3	T374	S373P	373	Missense	proximal	-1	no	6.136	6.140	EPSD	TCGA;ICGC;COSMIC	5.767	Up-regulation
CMGC_CDK_CDK2_CDK3_ST	Q8TDN4	CABLES1	Q00526	CDK3	S420	R413I	413	Missense	distal	-7	no	5.942	5.922	EPSD	TCGA;ICGC;COSMIC	5.767	Down-regulation
CMGC_CDK_CDK2_CDK3_ST	P06400	RB1	Q00526	CDK3	S230	F226L	226	Missense	distal	-4	no	7.509	7.482	EPSD	TCGA;ICGC;COSMIC	5.767	Down-regulation
CMGC_CDK_CDK2_CDK3_ST	P06400	RB1	Q00526	CDK3	S230	Y225C	225	Missense	distal	-5	no	7.509	7.734	EPSD	TCGA;ICGC	5.767	Up-regulation
CMGC_CDK_CDK2_CDK3_ST	P06400	RB1	Q00526	CDK3	S249	R255Q	255	Missense	distal	6	no	9.420	9.397	EPSD	TCGA;ICGC;COSMIC	5.767	Down-regulation
CMGC_CDK_CDK2_CDK3_ST	P06400	RB1	Q00526	CDK3	S249	R251Q	251	Missense	proximal	2	no	9.420	9.404	EPSD	TCGA;ICGC;COSMIC;CCLE	5.767	Down-regulation
CMGC_CDK_CDK2_CDK3_ST	P06400	RB1	Q00526	CDK3	S249	P245A	245	Missense	distal	-4	no	9.420	9.758	EPSD	TCGA;ICGC;COSMIC	5.767	Up-regulation
CMGC_CDK_CDK2_CDK3_ST	P06400	RB1	Q00526	CDK3	T252	R255Q	255	Missense	distal	3	no	6.845	7.216	EPSD	TCGA;ICGC;COSMIC	5.767	Up-regulation
CMGC_CDK_CDK2_CDK3_ST	P06400	RB1	Q00526	CDK3	T252	R251Q	251	Missense	proximal	-1	no	6.845	6.834	EPSD	TCGA;ICGC;COSMIC;CCLE	5.767	Down-regulation
CMGC_CDK_CDK2_CDK3_ST	P06400	RB1	Q00526	CDK3	T252	P245A	245	Missense	distal	-7	no	6.845	7.092	EPSD	TCGA;ICGC;COSMIC	5.767	Up-regulation
CMGC_CDK_CDK2_CDK3_ST	P06400	RB1	Q00526	CDK3	T252	R259S	259	Missense	distal	7	no	6.845	6.817	EPSD	TCGA;ICGC;COSMIC	5.767	Down-regulation
CMGC_CDK_CDK2_CDK3_ST	P06400	RB1	Q00526	CDK3	T356	S350I	350	Missense	distal	-6	no	5.377	6.330	EPSD	TCGA;ICGC;COSMIC;GDSC	5.767	Gain
CMGC_CDK_CDK2_CDK3_ST	P06400	RB1	Q00526	CDK3	T373	P374A	374	Missense	proximal	1	no	6.520	1.114	EPSD	TCGA;ICGC;COSMIC	5.767	Loss
CMGC_CDK_CDK2_CDK3_ST	P06400	RB1	Q00526	CDK3	T373	M379L	379	Missense	distal	6	no	6.520	6.518	EPSD	TCGA;ICGC;COSMIC	5.767	Down-regulation
CMGC_CDK_CDK2_CDK3_ST	P06400	RB1	Q00526	CDK3	S414	E413Q	413	Missense	proximal	-1	no	5.918	5.915	EPSD	TCGA;ICGC;COSMIC	5.767	Down-regulation
CMGC_CDK_CDK2_CDK3_ST	P06400	RB1	Q00526	CDK3	S567	S567L	567	Missense	central	0	yes	7.495	0.000	EPSD	TCGA;ICGC;COSMIC	5.767	Loss
CMGC_CDK_CDK2_CDK3_ST	P06400	RB1	Q00526	CDK3	S567	W563S	563	Missense	distal	-4	no	7.495	8.651	EPSD	TCGA;ICGC;COSMIC	5.767	Up-regulation
CMGC_CDK_CDK2_CDK3_ST	P06400	RB1	Q00526	CDK3	S567	A562E	562	Missense	distal	-5	no	7.495	7.748	EPSD	TCGA;ICGC;COSMIC	5.767	Up-regulation
CMGC_CDK_CDK2_CDK3_ST	P06400	RB1	Q00526	CDK3	S608	D604G	604	Missense	distal	-4	no	6.784	6.303	EPSD	TCGA;ICGC;COSMIC	5.767	Down-regulation
CMGC_CDK_CDK2_CDK3_ST	P06400	RB1	Q00526	CDK3	S624	Q631H	631	Missense	distal	7	no	6.737	6.731	EPSD	TCGA;ICGC;COSMIC	5.767	Down-regulation
CMGC_CDK_CDK2_CDK3_ST	P06400	RB1	Q00526	CDK3	S624	S624Y	624	Missense	central	0	yes	6.737	0.000	EPSD	TCGA;ICGC;COSMIC	5.767	Loss
CMGC_CDK_CDK2_CDK3_ST	P06400	RB1	Q00526	CDK3	S624	R621H	621	Missense	distal	-3	no	6.737	6.650	EPSD	TCGA;ICGC;COSMIC;CCLE	5.767	Down-regulation
CMGC_CDK_CDK2_CDK3_ST	P06400	RB1	Q00526	CDK3	S780	I782M	782	Missense	proximal	2	no	9.001	9.208	EPSD	TCGA;ICGC;COSMIC	5.767	Up-regulation
CMGC_CDK_CDK2_CDK3_ST	P06400	RB1	Q00526	CDK3	S780	R787Q	787	Missense	distal	7	no	9.001	8.983	EPSD	TCGA;ICGC;COSMIC	5.767	Down-regulation
CMGC_CDK_CDK2_CDK3_ST	P06400	RB1	Q00526	CDK3	S788	I782M	782	Missense	distal	-6	no	7.305	7.025	EPSD	TCGA;ICGC;COSMIC	5.767	Down-regulation
CMGC_CDK_CDK2_CDK3_ST	P06400	RB1	Q00526	CDK3	S788	S788N	788	Missense	central	0	yes	7.305	0.000	EPSD	TCGA;ICGC;COSMIC	5.767	Loss
CMGC_CDK_CDK2_CDK3_ST	P06400	RB1	Q00526	CDK3	S788	R787Q	787	Missense	proximal	-1	no	7.305	7.294	EPSD	TCGA;ICGC;COSMIC	5.767	Down-regulation
CMGC_CDK_CDK2_CDK3_ST	P06400	RB1	Q00526	CDK3	S795	S788N	788	Missense	distal	-7	no	7.086	7.242	EPSD	TCGA;ICGC;COSMIC	5.767	Up-regulation
CMGC_CDK_CDK2_CDK3_ST	P06400	RB1	Q00526	CDK3	S795	R798W	798	Missense	distal	3	no	7.086	7.559	EPSD	TCGA;ICGC;COSMIC;GDSC	5.767	Up-regulation
CMGC_CDK_CDK2_CDK3_ST	P06400	RB1	Q00526	CDK3	S807	N803S	803	Missense	distal	-4	no	13.237	13.728	PhosphoSitePlus;EPSD	TCGA;ICGC	5.767	Up-regulation
CMGC_CDK_CDK2_CDK3_ST	P06400	RB1	Q00526	CDK3	T821	P827S	827	Missense	distal	6	no	6.209	6.173	EPSD	TCGA;ICGC;COSMIC	5.767	Down-regulation
CMGC_CDK_CDK2_CDK3_ST	P06400	RB1	Q00526	CDK3	T826	P827S	827	Missense	proximal	1	no	8.468	3.404	EPSD	TCGA;ICGC;COSMIC	5.767	Loss
CMGC_CDK_CDK2_CDK3_ST	P06400	RB1	Q00526	CDK3	S866	G865V	865	Missense	proximal	-1	no	6.000	5.998	EPSD	TCGA;ICGC;COSMIC	5.767	Down-regulation
CMGC_CDK_CDK2_CDK3_ST	P06400	RB1	Q00526	CDK3	S866	K860R	860	Missense	distal	-6	no	6.000	6.515	EPSD	TCGA;ICGC;COSMIC	5.767	Up-regulation
Other_WNK_WNK2_ST	Q9UEW8	STK39	Q9Y3S1	WNK2	T224	V223F	223	Missense	proximal	-1	no	2.550	2.481	EPSD	TCGA;ICGC;COSMIC	2.413	Down-regulation
Other_WNK_WNK2_ST	Q9UEW8	STK39	Q9Y3S1	WNK2	T224	A218T	218	Missense	distal	-6	no	2.550	2.586	EPSD	TCGA;ICGC;COSMIC	2.413	Up-regulation
Other_WNK_WNK2_ST	Q9UEW8	STK39	Q9Y3S1	WNK2	T224	R225Q	225	Missense	proximal	1	no	2.550	2.301	EPSD	TCGA;ICGC;COSMIC	2.413	Loss
Other_WNK_WNK2_ST	Q9UEW8	STK39	Q9Y3S1	WNK2	T231	V233I	233	Missense	proximal	2	no	2.327	2.474	EPSD	TCGA;ICGC;COSMIC	2.413	Gain
Other_WNK_WNK2_ST	Q9UEW8	STK39	Q9Y3S1	WNK2	T354	R353I	353	Missense	proximal	-1	no	7.924	7.771	PhosphoSitePlus;EPSD	TCGA;ICGC;COSMIC	2.413	Down-regulation
Other_WNK_WNK2_ST	Q9H4A3	WNK1	Q9Y3S1	WNK2	T72	T74A	74	Missense	proximal	2	no	3.150	3.158	EPSD	TCGA;ICGC;COSMIC	2.413	Up-regulation
Other_WNK_WNK2_ST	Q9H4A3	WNK1	Q9Y3S1	WNK2	S382	E388Q	388	Missense	distal	6	no	8.337	8.120	PhosphoSitePlus	TCGA;ICGC;COSMIC	2.413	Down-regulation
Other_WNK_WNK2_ST	Q9H4A3	WNK1	Q9Y3S1	WNK2	S382	R376W	376	Missense	distal	-6	no	8.337	7.100	PhosphoSitePlus	TCGA;ICGC	2.413	Down-regulation
Other_WNK_WNK2_ST	Q9H4A3	WNK1	Q9Y3S1	WNK2	S597	A598V	598	Missense	proximal	1	no	2.940	3.258	EPSD	TCGA;COSMIC	2.413	Up-regulation
Other_WNK_WNK2_ST	Q9H4A3	WNK1	Q9Y3S1	WNK2	T1115	R1109L	1109	Missense	distal	-6	no	2.453	1.464	EPSD	TCGA;COSMIC	2.413	Loss
Other_WNK_WNK2_ST	Q9H4A3	WNK1	Q9Y3S1	WNK2	T1115	R1109H	1109	Missense	distal	-6	no	2.453	1.413	EPSD	TCGA	2.413	Loss
Other_WNK_WNK2_ST	Q9H4A3	WNK1	Q9Y3S1	WNK2	T1115	R1111Q	1111	Missense	distal	-4	no	2.453	2.457	EPSD	TCGA	2.413	Up-regulation
Other_WNK_WNK2_ST	Q9H4A3	WNK1	Q9Y3S1	WNK2	S1193	K1187E	1187	Missense	distal	-6	no	2.683	3.526	EPSD	TCGA;COSMIC	2.413	Up-regulation
Other_WNK_WNK2_ST	Q9H4A3	WNK1	Q9Y3S1	WNK2	S1246	S1253F	1253	Missense	distal	7	no	3.354	3.395	EPSD	TCGA;COSMIC	2.413	Up-regulation
Other_WNK_WNK2_ST	Q9H4A3	WNK1	Q9Y3S1	WNK2	S1246	S1246Y	1246	Missense	central	0	yes	3.354	0.000	EPSD	TCGA;COSMIC	2.413	Loss
Other_WNK_WNK2_ST	Q9H4A3	WNK1	Q9Y3S1	WNK2	S1961	F1958L	1958	Missense	distal	-3	no	2.786	2.758	EPSD	TCGA;COSMIC	2.413	Down-regulation
Other_WNK_WNK2_ST	Q9H4A3	WNK1	Q9Y3S1	WNK2	S1961	R1957C	1957	Missense	distal	-4	no	2.786	2.807	EPSD	TCGA;COSMIC	2.413	Up-regulation
Other_WNK_WNK2_ST	Q9H4A3	WNK1	Q9Y3S1	WNK2	S1961	R1957H	1957	Missense	distal	-4	no	2.786	2.803	EPSD	TCGA;COSMIC	2.413	Up-regulation
Other_WNK_WNK2_ST	Q9H4A3	WNK1	Q9Y3S1	WNK2	T1963	F1958L	1958	Missense	distal	-5	no	2.354	2.583	EPSD	TCGA;COSMIC	2.413	Gain
Other_WNK_WNK2_ST	Q9H4A3	WNK1	Q9Y3S1	WNK2	S2032	Q2035H	2035	Missense	distal	3	no	2.474	2.490	EPSD	TCGA;COSMIC	2.413	Up-regulation
Other_WNK_WNK2_ST	Q9H4A3	WNK1	Q9Y3S1	WNK2	S2032	G2028S	2028	Missense	distal	-4	no	2.474	2.446	EPSD	TCGA;GDSC;CCLE	2.413	Down-regulation
Other_WNK_WNK2_ST	Q9H4A3	WNK1	Q9Y3S1	WNK2	S2145	L2148F	2148	Missense	distal	3	no	2.643	2.622	EPSD	TCGA;COSMIC	2.413	Down-regulation
Other_WNK_WNK2_ST	Q9H4A3	WNK1	Q9Y3S1	WNK2	S2145	S2145N	2145	Missense	central	0	yes	2.643	0.000	EPSD	TCGA;COSMIC	2.413	Loss
TK_Trk_NTRK2_Y	P22001	KCNA3	Q16620	NTRK2	Y485	Y485D	485	Missense	central	0	yes	0.000	0.000	EPSD	TCGA;ICGC;COSMIC	0.000	Loss
AGC_RSK_MSK_RPS6KA4_ST	P16220	CREB1	O75676	RPS6KA4	S98	S103A	103	Missense	distal	5	no	2.588	2.579	EPSD	TCGA;COSMIC	2.457	Down-regulation
AGC_RSK_MSK_RPS6KA4_ST	P16220	CREB1	O75676	RPS6KA4	S103	S103A	103	Missense	central	0	yes	2.746	0.000	EPSD	TCGA;COSMIC	2.457	Loss
AGC_RSK_MSK_RPS6KA4_ST	P16220	CREB1	O75676	RPS6KA4	S133	L128I	128	Missense	distal	-5	no	9.316	9.252	PhosphoSitePlus	TCGA;COSMIC	2.457	Down-regulation
AGC_RSK_MSK_RPS6KA4_ST	P54253	ATXN1	O75676	RPS6KA4	S25	E27K	27	Missense	proximal	2	no	2.589	2.575	EPSD	TCGA;ICGC;COSMIC	2.457	Down-regulation
AGC_RSK_MSK_RPS6KA4_ST	P54253	ATXN1	O75676	RPS6KA4	S26	E27K	27	Missense	proximal	1	no	3.629	3.604	EPSD	TCGA;ICGC;COSMIC	2.457	Down-regulation
AGC_RSK_MSK_RPS6KA4_ST	P54253	ATXN1	O75676	RPS6KA4	S262	P264L	264	Missense	proximal	2	no	3.049	3.045	EPSD	TCGA;ICGC;COSMIC	2.457	Down-regulation
AGC_RSK_MSK_RPS6KA4_ST	P54253	ATXN1	O75676	RPS6KA4	S262	P267L	267	Missense	distal	5	no	3.049	3.141	EPSD	TCGA;ICGC;COSMIC	2.457	Up-regulation
AGC_RSK_MSK_RPS6KA4_ST	P54253	ATXN1	O75676	RPS6KA4	S262	V268I	268	Missense	distal	6	no	3.049	3.038	EPSD	TCGA;ICGC;COSMIC;CCLE	2.457	Down-regulation
AGC_RSK_MSK_RPS6KA4_ST	P54253	ATXN1	O75676	RPS6KA4	S312	E310K	310	Missense	proximal	-2	no	2.446	2.872	EPSD	TCGA;ICGC;COSMIC	2.457	Gain
AGC_RSK_MSK_RPS6KA4_ST	P54253	ATXN1	O75676	RPS6KA4	S339	P337R	337	Missense	proximal	-2	no	0.739	3.117	EPSD	TCGA;ICGC;COSMIC	2.457	Gain
AGC_RSK_MSK_RPS6KA4_ST	P54253	ATXN1	O75676	RPS6KA4	S775	A776V	776	Missense	proximal	1	no	4.941	4.965	PhosphoSitePlus	TCGA;ICGC;COSMIC	2.457	Up-regulation
AGC_RSK_MSK_RPS6KA4_ST	P54253	ATXN1	O75676	RPS6KA4	S775	K771E	771	Missense	distal	-4	no	4.941	4.942	PhosphoSitePlus	TCGA;ICGC;COSMIC;GDSC;CCLE	2.457	Up-regulation
AGC_RSK_MSK_RPS6KA4_ST	Q04206	RELA	O75676	RPS6KA4	S203	D210Y	210	Missense	distal	7	no	3.044	3.085	EPSD	TCGA;ICGC;COSMIC	2.457	Up-regulation
AGC_RSK_MSK_RPS6KA4_ST	Q04206	RELA	O75676	RPS6KA4	S203	G208S	208	Missense	distal	5	no	3.044	3.246	EPSD	TCGA;ICGC;COSMIC;GDSC;CCLE	2.457	Up-regulation
AGC_RSK_MSK_RPS6KA4_ST	Q04206	RELA	O75676	RPS6KA4	S261	P256S	256	Missense	distal	-5	no	2.924	3.026	EPSD	TCGA;ICGC;COSMIC	2.457	Up-regulation
AGC_RSK_MSK_RPS6KA4_ST	Q04206	RELA	O75676	RPS6KA4	S261	P256L	256	Missense	distal	-5	no	2.924	3.008	EPSD	TCGA;ICGC;COSMIC	2.457	Up-regulation
AGC_RSK_MSK_RPS6KA4_ST	Q04206	RELA	O75676	RPS6KA4	S261	A258V	258	Missense	distal	-3	no	2.924	2.637	EPSD	TCGA;ICGC;COSMIC	2.457	Down-regulation
AGC_RSK_MSK_RPS6KA4_ST	Q04206	RELA	O75676	RPS6KA4	S269	S276F	276	Missense	distal	7	no	2.721	2.697	EPSD	TCGA;ICGC;COSMIC	2.457	Down-regulation
AGC_RSK_MSK_RPS6KA4_ST	Q04206	RELA	O75676	RPS6KA4	S269	R274W	274	Missense	distal	5	no	2.721	2.683	EPSD	TCGA;ICGC	2.457	Down-regulation
AGC_RSK_MSK_RPS6KA4_ST	Q04206	RELA	O75676	RPS6KA4	S269	R273W	273	Missense	distal	4	no	2.721	2.749	EPSD	TCGA;ICGC	2.457	Up-regulation
AGC_RSK_MSK_RPS6KA4_ST	Q04206	RELA	O75676	RPS6KA4	S276	S276F	276	Missense	central	0	yes	9.456	0.000	PhosphoSitePlus	TCGA;ICGC;COSMIC	2.457	Loss
AGC_RSK_MSK_RPS6KA4_ST	Q04206	RELA	O75676	RPS6KA4	S276	R274W	274	Missense	proximal	-2	no	9.456	7.449	PhosphoSitePlus	TCGA;ICGC	2.457	Down-regulation
AGC_RSK_MSK_RPS6KA4_ST	Q04206	RELA	O75676	RPS6KA4	S276	R273W	273	Missense	distal	-3	no	9.456	8.134	PhosphoSitePlus	TCGA;ICGC	2.457	Down-regulation
AGC_RSK_MSK_RPS6KA4_ST	Q04206	RELA	O75676	RPS6KA4	S281	S276F	276	Missense	distal	-5	no	3.852	3.805	EPSD	TCGA;ICGC;COSMIC	2.457	Down-regulation
AGC_RSK_MSK_RPS6KA4_ST	Q04206	RELA	O75676	RPS6KA4	S281	R274W	274	Missense	distal	-7	no	3.852	3.606	EPSD	TCGA;ICGC	2.457	Down-regulation
AGC_RSK_MSK_RPS6KA4_ST	Q04206	RELA	O75676	RPS6KA4	T305	F309L	309	Missense	distal	4	no	2.640	2.628	EPSD	TCGA;ICGC;COSMIC	2.457	Down-regulation
AGC_RSK_MSK_RPS6KA4_ST	Q04206	RELA	O75676	RPS6KA4	T305	E307K	307	Missense	proximal	2	no	2.640	2.626	EPSD	TCGA;ICGC;COSMIC	2.457	Down-regulation
AGC_RSK_MSK_RPS6KA4_ST	Q04206	RELA	O75676	RPS6KA4	T305	T308A	308	Missense	distal	3	no	2.640	2.451	EPSD	TCGA;ICGC;COSMIC	2.457	Loss
AGC_RSK_MSK_RPS6KA4_ST	Q04206	RELA	O75676	RPS6KA4	T308	F309L	309	Missense	proximal	1	no	2.492	2.442	EPSD	TCGA;ICGC;COSMIC	2.457	Loss
AGC_RSK_MSK_RPS6KA4_ST	Q04206	RELA	O75676	RPS6KA4	T308	T308A	308	Missense	central	0	yes	2.492	0.000	EPSD	TCGA;ICGC;COSMIC	2.457	Loss
AGC_RSK_MSK_RPS6KA4_ST	Q04206	RELA	O75676	RPS6KA4	S311	F309L	309	Missense	proximal	-2	no	3.231	3.038	EPSD	TCGA;ICGC;COSMIC	2.457	Down-regulation
AGC_RSK_MSK_RPS6KA4_ST	Q04206	RELA	O75676	RPS6KA4	S311	T308A	308	Missense	distal	-3	no	3.231	2.924	EPSD	TCGA;ICGC;COSMIC	2.457	Down-regulation
AGC_RSK_MSK_RPS6KA4_ST	Q04206	RELA	O75676	RPS6KA4	S338	A339T	339	Missense	proximal	1	no	4.164	4.214	EPSD	TCGA;ICGC;COSMIC;CCLE	2.457	Up-regulation
AGC_RSK_MSK_RPS6KA4_ST	Q04206	RELA	O75676	RPS6KA4	S338	A332D	332	Missense	distal	-6	no	4.164	4.165	EPSD	TCGA;ICGC	2.457	Up-regulation
AGC_RSK_MSK_RPS6KA4_ST	Q04206	RELA	O75676	RPS6KA4	S340	A339T	339	Missense	proximal	-1	no	2.941	2.907	EPSD	TCGA;ICGC;COSMIC;CCLE	2.457	Down-regulation
AGC_RSK_MSK_RPS6KA4_ST	O75676	RPS6KA4	O75676	RPS6KA4	T178	D179N	179	Missense	proximal	1	no	3.288	3.252	EPSD	TCGA;ICGC;COSMIC	2.457	Down-regulation
AGC_RSK_MSK_RPS6KA4_ST	O75676	RPS6KA4	O75676	RPS6KA4	S196	T200I	200	Missense	distal	4	no	8.480	8.506	PhosphoSitePlus	TCGA;ICGC	2.457	Up-regulation
AGC_RSK_MSK_RPS6KA4_ST	O75676	RPS6KA4	O75676	RPS6KA4	S433	R429C	429	Missense	distal	-4	no	3.104	3.098	EPSD	TCGA;COSMIC	2.457	Down-regulation
AGC_RSK_MSK_RPS6KA4_ST	O75676	RPS6KA4	O75676	RPS6KA4	S634	G637R	637	Missense	distal	3	no	4.360	3.542	EPSD	TCGA;COSMIC	2.457	Down-regulation
AGC_RSK_MSK_RPS6KA4_ST	O75676	RPS6KA4	O75676	RPS6KA4	S634	E630K	630	Missense	distal	-4	no	4.360	4.359	EPSD	TCGA	2.457	Down-regulation
AGC_RSK_MSK_RPS6KA4_ST	O75676	RPS6KA4	O75676	RPS6KA4	S634	R629C	629	Missense	distal	-5	no	4.360	4.431	EPSD	TCGA;COSMIC	2.457	Up-regulation
AGC_RSK_MSK_RPS6KA4_ST	O75676	RPS6KA4	O75676	RPS6KA4	S671	G677D	677	Missense	distal	6	no	3.640	3.472	EPSD	TCGA;COSMIC	2.457	Down-regulation
AGC_RSK_MSK_RPS6KA4_ST	O75676	RPS6KA4	O75676	RPS6KA4	S682	P684S	684	Missense	proximal	2	no	3.084	3.078	EPSD	TCGA;COSMIC;CCLE	2.457	Down-regulation
AGC_RSK_MSK_RPS6KA4_ST	O75676	RPS6KA4	O75676	RPS6KA4	S682	G677D	677	Missense	distal	-5	no	3.084	3.088	EPSD	TCGA;COSMIC	2.457	Up-regulation
AGC_RSK_MSK_RPS6KA4_ST	O75676	RPS6KA4	O75676	RPS6KA4	S745	R742L	742	Missense	distal	-3	no	3.872	2.363	EPSD	TCGA;ICGC;COSMIC	2.457	Loss
AGC_RSK_MSK_RPS6KA4_ST	O75676	RPS6KA4	O75676	RPS6KA4	S745	T739I	739	Missense	distal	-6	no	3.872	3.871	EPSD	TCGA;COSMIC	2.457	Down-regulation
TKL_MLK_ILK_ILK_ST	O14950	MYL12B	Q13418	ILK	T19	R17C	17	Missense	proximal	-2	no	21.935	16.461	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	15.108	Down-regulation
TKL_MLK_ILK_ILK_ST	O14950	MYL12B	Q13418	ILK	S20	R17C	17	Missense	distal	-3	no	20.941	19.302	PhosphoSitePlus;EPSD	TCGA;ICGC;COSMIC	15.108	Down-regulation
TKL_MLK_ILK_ILK_ST	O14950	MYL12B	Q13418	ILK	T135	D136Y	136	Missense	proximal	1	no	15.716	16.556	EPSD	TCGA;ICGC;COSMIC	15.108	Up-regulation
TKL_MLK_ILK_ILK_ST	O14950	MYL12B	Q13418	ILK	T135	F134L	134	Missense	proximal	-1	no	15.716	15.946	EPSD	TCGA;ICGC;COSMIC	15.108	Up-regulation
TKL_MLK_ILK_ILK_ST	P31749	AKT1	Q13418	ILK	T34	G33D	33	Missense	proximal	-1	no	18.369	18.622	EPSD	TCGA;COSMIC	15.108	Up-regulation
TKL_MLK_ILK_ILK_ST	P31749	AKT1	Q13418	ILK	T34	E40K	40	Missense	distal	6	no	18.369	18.680	EPSD	TCGA;ICGC;COSMIC;CCLE	15.108	Up-regulation
TKL_MLK_ILK_ILK_ST	P31749	AKT1	Q13418	ILK	T65	T65M	65	Missense	central	0	yes	15.698	0.000	EPSD	TCGA;ICGC;COSMIC	15.108	Loss
TKL_MLK_ILK_ILK_ST	P31749	AKT1	Q13418	ILK	T65	R69W	69	Missense	distal	4	no	15.698	15.772	EPSD	TCGA;ICGC;COSMIC	15.108	Up-regulation
TKL_MLK_ILK_ILK_ST	P31749	AKT1	Q13418	ILK	T430	P423T	423	Missense	distal	-7	no	23.358	23.361	EPSD	TCGA;ICGC	15.108	Up-regulation
TKL_MLK_ILK_ILK_ST	P31749	AKT1	Q13418	ILK	T430	S431L	431	Missense	proximal	1	no	23.358	22.443	EPSD	TCGA;ICGC;COSMIC	15.108	Down-regulation
TKL_MLK_ILK_ILK_ST	Q96A00	PPP1R14A	Q13418	ILK	T38	R36C	36	Missense	proximal	-2	no	44.965	39.492	PhosphoSitePlus	TCGA;ICGC;COSMIC	15.108	Down-regulation
TKL_MLK_ILK_ILK_ST	Q96A00	PPP1R14A	Q13418	ILK	T38	R44W	44	Missense	distal	6	no	44.965	43.589	PhosphoSitePlus	TCGA;ICGC;COSMIC	15.108	Down-regulation
TKL_MLK_ILK_ILK_ST	Q8TAE6	PPP1R14C	Q13418	ILK	S47	A51T	51	Missense	distal	4	no	16.626	16.666	EPSD	TCGA;ICGC;COSMIC	15.108	Up-regulation
TKL_MLK_ILK_ILK_ST	Q8TAE6	PPP1R14C	Q13418	ILK	S47	A54V	54	Missense	distal	7	no	16.626	15.861	EPSD	TCGA;ICGC	15.108	Down-regulation
TKL_MLK_ILK_ILK_ST	Q96C90	PPP1R14B	Q13418	ILK	T57	V50L	50	Missense	distal	-7	no	41.632	41.630	PhosphoSitePlus	TCGA;ICGC;COSMIC	15.108	Down-regulation
TKL_LISK_TESK_TESK1_ST	P23528	CFL1	Q15569	TESK1	S3	D9N	9	Missense	distal	6	no	9.660	9.544	PhosphoSitePlus	TCGA;COSMIC	1.889	Down-regulation
CK1_VRK_VRK1_ST	P38432	COIL	Q99986	VRK1	S129	D125H	125	Missense	distal	-4	no	0.325	0.306	EPSD	TCGA;ICGC;COSMIC	0.296	Down-regulation
CK1_VRK_VRK1_ST	P38432	COIL	Q99986	VRK1	S184	C191Y	191	Missense	distal	7	no	0.498	0.496	PhosphoSitePlus	TCGA;ICGC;COSMIC	0.296	Down-regulation
CK1_VRK_VRK1_ST	P38432	COIL	Q99986	VRK1	S184	K186T	186	Missense	proximal	2	no	0.498	0.476	PhosphoSitePlus	TCGA;ICGC;COSMIC	0.296	Down-regulation
CK1_VRK_VRK1_ST	P38432	COIL	Q99986	VRK1	S316	A321V	321	Missense	distal	5	no	0.297	0.307	EPSD	TCGA;ICGC;COSMIC	0.296	Up-regulation
CK1_VRK_VRK1_ST	P38432	COIL	Q99986	VRK1	S317	A321V	321	Missense	distal	4	no	0.331	0.305	EPSD	TCGA;ICGC;COSMIC	0.296	Down-regulation
CK1_VRK_VRK1_ST	P38432	COIL	Q99986	VRK1	T570	S566T	566	Missense	distal	-4	no	0.244	0.297	EPSD	TCGA;ICGC;COSMIC	0.296	Gain
CK1_VRK_VRK1_ST	P05412	JUN	Q99986	VRK1	S73	S73L	73	Missense	central	0	yes	0.503	0.000	PhosphoSitePlus;EPSD	TCGA;ICGC;COSMIC	0.296	Loss
CK1_VRK_VRK1_ST	P15336	ATF2	Q99986	VRK1	S100	E93Q	93	Missense	distal	-7	no	0.327	0.282	EPSD	TCGA;COSMIC	0.296	Loss
CK1_VRK_VRK1_ST	P15336	ATF2	Q99986	VRK1	T116	T116A	116	Missense	central	0	yes	0.320	0.000	EPSD	TCGA;COSMIC	0.296	Loss
CK1_VRK_VRK1_ST	P15336	ATF2	Q99986	VRK1	T116	S112P	112	Missense	distal	-4	no	0.320	0.318	EPSD	TCGA;COSMIC	0.296	Down-regulation
CK1_VRK_VRK1_ST	P15336	ATF2	Q99986	VRK1	S136	D135N	135	Missense	proximal	-1	no	0.374	0.376	EPSD	TCGA	0.296	Up-regulation
CK1_VRK_VRK1_ST	P15336	ATF2	Q99986	VRK1	S136	S136N	136	Missense	central	0	yes	0.374	0.000	EPSD	TCGA	0.296	Loss
CK1_VRK_VRK1_ST	P15336	ATF2	Q99986	VRK1	T305	P312L	312	Missense	distal	7	no	0.369	0.389	EPSD	TCGA;COSMIC	0.296	Up-regulation
CK1_VRK_VRK1_ST	P15336	ATF2	Q99986	VRK1	T305	E308Q	308	Missense	distal	3	no	0.369	0.380	EPSD	TCGA;COSMIC	0.296	Up-regulation
CK1_VRK_VRK1_ST	P15336	ATF2	Q99986	VRK1	T305	R304S	304	Missense	proximal	-1	no	0.369	0.370	EPSD	TCGA;COSMIC	0.296	Up-regulation
CK1_VRK_VRK1_ST	P15336	ATF2	Q99986	VRK1	T305	S310F	310	Missense	distal	5	no	0.369	0.368	EPSD	TCGA;COSMIC	0.296	Down-regulation
CK1_VRK_VRK1_ST	P15336	ATF2	Q99986	VRK1	S310	P312L	312	Missense	proximal	2	no	0.396	0.365	EPSD	TCGA;COSMIC	0.296	Down-regulation
CK1_VRK_VRK1_ST	P15336	ATF2	Q99986	VRK1	S310	E308Q	308	Missense	proximal	-2	no	0.396	0.398	EPSD	TCGA;COSMIC	0.296	Up-regulation
CK1_VRK_VRK1_ST	P15336	ATF2	Q99986	VRK1	S310	R304S	304	Missense	distal	-6	no	0.396	0.416	EPSD	TCGA;COSMIC	0.296	Up-regulation
CK1_VRK_VRK1_ST	P15336	ATF2	Q99986	VRK1	S310	S310F	310	Missense	central	0	yes	0.396	0.000	EPSD	TCGA;COSMIC	0.296	Loss
CK1_VRK_VRK1_ST	P04637	TP53	Q99986	VRK1	S149	P152L	152	Missense	distal	3	no	0.377	0.389	EPSD	TCGA;ICGC;COSMIC;GDSC;CCLE	0.296	Up-regulation
CK1_VRK_VRK1_ST	P04637	TP53	Q99986	VRK1	S149	D148N	148	Missense	proximal	-1	no	0.377	0.379	EPSD	TCGA;ICGC;COSMIC	0.296	Up-regulation
CK1_VRK_VRK1_ST	P04637	TP53	Q99986	VRK1	S149	P151H	151	Missense	proximal	2	no	0.377	0.368	EPSD	TCGA;ICGC;COSMIC;GDSC;CCLE	0.296	Down-regulation
CK1_VRK_VRK1_ST	P04637	TP53	Q99986	VRK1	S149	P151A	151	Missense	proximal	2	no	0.377	0.380	EPSD	TCGA;ICGC;COSMIC;CCLE	0.296	Up-regulation
CK1_VRK_VRK1_ST	P04637	TP53	Q99986	VRK1	S149	R156P	156	Missense	distal	7	no	0.377	0.367	EPSD	TCGA;ICGC;COSMIC;GDSC;CCLE	0.296	Down-regulation
CK1_VRK_VRK1_ST	P04637	TP53	Q99986	VRK1	S149	V143A	143	Missense	distal	-6	no	0.377	0.293	EPSD	TCGA;ICGC;COSMIC;GDSC;CCLE	0.296	Loss
CK1_VRK_VRK1_ST	P04637	TP53	Q99986	VRK1	S149	P151S	151	Missense	proximal	2	no	0.377	0.394	EPSD	TCGA;ICGC;COSMIC;GDSC;CCLE	0.296	Up-regulation
CK1_VRK_VRK1_ST	P04637	TP53	Q99986	VRK1	S149	L145R	145	Missense	distal	-4	no	0.377	0.342	EPSD	TCGA;ICGC;COSMIC;GDSC;CCLE	0.296	Down-regulation
CK1_VRK_VRK1_ST	P04637	TP53	Q99986	VRK1	S149	T155I	155	Missense	distal	6	no	0.377	0.367	EPSD	TCGA;ICGC;COSMIC;CCLE	0.296	Down-regulation
CK1_VRK_VRK1_ST	P04637	TP53	Q99986	VRK1	S149	V143M	143	Missense	distal	-6	no	0.377	0.320	EPSD	TCGA;ICGC;COSMIC;GDSC;CCLE	0.296	Down-regulation
CK1_VRK_VRK1_ST	P04637	TP53	Q99986	VRK1	S149	T155N	155	Missense	distal	6	no	0.377	0.363	EPSD	TCGA;ICGC;COSMIC;GDSC;CCLE	0.296	Down-regulation
CK1_VRK_VRK1_ST	P04637	TP53	Q99986	VRK1	S149	P152S	152	Missense	distal	3	no	0.377	0.382	EPSD	TCGA;ICGC;COSMIC;CCLE	0.296	Up-regulation
CK1_VRK_VRK1_ST	P04637	TP53	Q99986	VRK1	S149	R156C	156	Missense	distal	7	no	0.377	0.378	EPSD	TCGA;ICGC;COSMIC	0.296	Up-regulation
CK1_VRK_VRK1_ST	P04637	TP53	Q99986	VRK1	S149	P151T	151	Missense	proximal	2	no	0.377	0.368	EPSD	TCGA;ICGC;COSMIC	0.296	Down-regulation
CK1_VRK_VRK1_ST	P04637	TP53	Q99986	VRK1	S149	T155P	155	Missense	distal	6	no	0.377	0.388	EPSD	TCGA;ICGC;COSMIC;CCLE	0.296	Up-regulation
CK1_VRK_VRK1_ST	P04637	TP53	Q99986	VRK1	S149	V143G	143	Missense	distal	-6	no	0.377	0.420	EPSD	TCGA;ICGC;COSMIC	0.296	Up-regulation
CK1_VRK_VRK1_ST	P04637	TP53	Q99986	VRK1	S149	P152Q	152	Missense	distal	3	no	0.377	0.382	EPSD	TCGA;ICGC;COSMIC	0.296	Up-regulation
CK1_VRK_VRK1_ST	P04637	TP53	Q99986	VRK1	S149	R156H	156	Missense	distal	7	no	0.377	0.370	EPSD	TCGA;ICGC;COSMIC	0.296	Down-regulation
CK1_VRK_VRK1_ST	P04637	TP53	Q99986	VRK1	S149	P142L	142	Missense	distal	-7	no	0.377	0.350	EPSD	TCGA;ICGC;COSMIC	0.296	Down-regulation
CK1_VRK_VRK1_ST	P04637	TP53	Q99986	VRK1	S149	L145P	145	Missense	distal	-4	no	0.377	0.320	EPSD	TCGA;ICGC;COSMIC	0.296	Down-regulation
CK1_VRK_VRK1_ST	P04637	TP53	Q99986	VRK1	S149	Q144L	144	Missense	distal	-5	no	0.377	0.345	EPSD	TCGA;ICGC;COSMIC	0.296	Down-regulation
CK1_VRK_VRK1_ST	P04637	TP53	Q99986	VRK1	S149	Q144H	144	Missense	distal	-5	no	0.377	0.349	EPSD	TCGA;ICGC;COSMIC	0.296	Down-regulation
CK1_VRK_VRK1_ST	P04637	TP53	Q99986	VRK1	S149	G154V	154	Missense	distal	5	no	0.377	0.382	EPSD	TCGA;ICGC;COSMIC;GDSC;CCLE	0.296	Up-regulation
CK1_VRK_VRK1_ST	P04637	TP53	Q99986	VRK1	S149	P151R	151	Missense	proximal	2	no	0.377	0.370	EPSD	TCGA;ICGC;COSMIC	0.296	Down-regulation
CK1_VRK_VRK1_ST	P04637	TP53	Q99986	VRK1	S149	Q144P	144	Missense	distal	-5	no	0.377	0.373	EPSD	TCGA;ICGC;COSMIC	0.296	Down-regulation
CK1_VRK_VRK1_ST	P04637	TP53	Q99986	VRK1	S149	V143E	143	Missense	distal	-6	no	0.377	0.361	EPSD	TCGA;ICGC;COSMIC	0.296	Down-regulation
CK1_VRK_VRK1_ST	P04637	TP53	Q99986	VRK1	S149	R156G	156	Missense	distal	7	no	0.377	0.366	EPSD	TCGA;ICGC;COSMIC	0.296	Down-regulation
CK1_VRK_VRK1_ST	P04637	TP53	Q99986	VRK1	S149	P151L	151	Missense	proximal	2	no	0.377	0.346	EPSD	TCGA;ICGC;COSMIC	0.296	Down-regulation
CK1_VRK_VRK1_ST	Q99986	VRK1	Q99986	VRK1	T305	M303T	303	Missense	proximal	-2	no	0.338	0.341	EPSD	TCGA;ICGC;COSMIC	0.296	Up-regulation
CK1_VRK_VRK1_ST	Q99986	VRK1	Q99986	VRK1	T355	K359N	359	Missense	distal	4	no	0.477	0.436	PhosphoSitePlus	TCGA;ICGC	0.296	Down-regulation
CK1_VRK_VRK1_ST	Q99986	VRK1	Q99986	VRK1	T355	A351T	351	Missense	distal	-4	no	0.477	0.483	PhosphoSitePlus	TCGA;ICGC;COSMIC	0.296	Up-regulation
CK1_VRK_VRK1_ST	Q99986	VRK1	Q99986	VRK1	T355	K356N	356	Missense	proximal	1	no	0.477	0.468	PhosphoSitePlus	TCGA;ICGC;COSMIC	0.296	Down-regulation
CK1_VRK_VRK1_ST	Q99986	VRK1	Q99986	VRK1	T355	K356E	356	Missense	proximal	1	no	0.477	0.473	PhosphoSitePlus	TCGA;ICGC;COSMIC	0.296	Down-regulation
CK1_VRK_VRK1_ST	Q99986	VRK1	Q99986	VRK1	T378	E381K	381	Missense	distal	3	no	0.283	0.299	EPSD	TCGA;ICGC;COSMIC	0.296	Gain
AGC_PKC_PKCi_PRKCI_ST	Q7KZI7	MARK2	P41743	PRKCI	S30	R36W	36	Missense	distal	6	no	8.250	7.819	EPSD	TCGA;ICGC;COSMIC	6.376	Down-regulation
AGC_PKC_PKCi_PRKCI_ST	Q7KZI7	MARK2	P41743	PRKCI	S30	G37S	37	Missense	distal	7	no	8.250	8.346	EPSD	TCGA	6.376	Up-regulation
AGC_PKC_PKCi_PRKCI_ST	Q7KZI7	MARK2	P41743	PRKCI	S30	M34V	34	Missense	distal	4	no	8.250	8.680	EPSD	TCGA;ICGC;COSMIC	6.376	Up-regulation
AGC_PKC_PKCi_PRKCI_ST	Q7KZI7	MARK2	P41743	PRKCI	S43	R36W	36	Missense	distal	-7	no	5.365	6.716	EPSD	TCGA;ICGC;COSMIC	6.376	Gain
AGC_PKC_PKCi_PRKCI_ST	Q7KZI7	MARK2	P41743	PRKCI	S424	T427A	427	Missense	distal	3	no	10.983	11.102	EPSD	TCGA;COSMIC	6.376	Up-regulation
AGC_PKC_PKCi_PRKCI_ST	Q7KZI7	MARK2	P41743	PRKCI	S505	P509L	509	Missense	distal	4	no	6.311	6.504	EPSD	TCGA;COSMIC	6.376	Gain
AGC_PKC_PKCi_PRKCI_ST	Q7KZI7	MARK2	P41743	PRKCI	S533	R528C	528	Missense	distal	-5	no	8.460	3.430	EPSD	TCGA;COSMIC	6.376	Loss
AGC_PKC_PKCi_PRKCI_ST	Q7KZI7	MARK2	P41743	PRKCI	S569	P566S	566	Missense	distal	-3	no	6.087	8.356	EPSD	TCGA;COSMIC	6.376	Gain
AGC_PKC_PKCi_PRKCI_ST	Q7KZI7	MARK2	P41743	PRKCI	S571	P566S	566	Missense	distal	-5	no	5.921	7.110	EPSD	TCGA;COSMIC	6.376	Gain
AGC_PKC_PKCi_PRKCI_ST	Q7KZI7	MARK2	P41743	PRKCI	T596	H598N	598	Missense	proximal	2	no	11.061	10.767	PhosphoSitePlus	TCGA	6.376	Down-regulation
AGC_PKC_PKCi_PRKCI_ST	Q7KZI7	MARK2	P41743	PRKCI	T596	T596P	596	Missense	central	0	yes	11.061	0.000	PhosphoSitePlus	TCGA;COSMIC	6.376	Loss
AGC_PKC_PKCi_PRKCI_ST	Q7KZI7	MARK2	P41743	PRKCI	T596	R594Q	594	Missense	proximal	-2	no	11.061	10.606	PhosphoSitePlus	TCGA;COSMIC	6.376	Down-regulation
AGC_PKC_PKCi_PRKCI_ST	Q7KZI7	MARK2	P41743	PRKCI	T667	P670L	670	Missense	distal	3	no	9.657	9.860	EPSD	TCGA;COSMIC	6.376	Up-regulation
AGC_PKC_PKCi_PRKCI_ST	Q7KZI7	MARK2	P41743	PRKCI	T667	T667M	667	Missense	central	0	yes	9.657	0.000	EPSD	TCGA;COSMIC	6.376	Loss
AGC_PKC_PKCi_PRKCI_ST	Q7KZI7	MARK2	P41743	PRKCI	S692	R686W	686	Missense	distal	-6	no	5.496	6.645	EPSD	TCGA;COSMIC	6.376	Gain
AGC_PKC_PKCi_PRKCI_ST	Q7KZI7	MARK2	P41743	PRKCI	S769	S769L	769	Missense	central	0	yes	8.015	0.000	EPSD	TCGA;COSMIC	6.376	Loss
AGC_PKC_PKCi_PRKCI_ST	Q7KZI7	MARK2	P41743	PRKCI	S769	R767W	767	Missense	proximal	-2	no	8.015	6.877	EPSD	TCGA	6.376	Down-regulation
AGC_PKC_PKCi_PRKCI_ST	Q4VCS5	AMOT	P41743	PRKCI	S175	L174F	174	Missense	proximal	-1	no	6.276	6.386	EPSD	TCGA	6.376	Gain
AGC_PKC_PKCi_PRKCI_ST	Q4VCS5	AMOT	P41743	PRKCI	S419	Y420F	420	Missense	proximal	1	no	5.238	8.405	EPSD	TCGA;COSMIC	6.376	Gain
AGC_PKC_PKCi_PRKCI_ST	Q4VCS5	AMOT	P41743	PRKCI	T536	S538L	538	Missense	proximal	2	no	7.335	6.660	PhosphoSitePlus;EPSD	TCGA;COSMIC	6.376	Down-regulation
AGC_PKC_PKCi_PRKCI_ST	Q4VCS5	AMOT	P41743	PRKCI	T536	R534I	534	Missense	proximal	-2	no	7.335	6.441	PhosphoSitePlus;EPSD	TCGA;COSMIC;CCLE	6.376	Down-regulation
AGC_PKC_PKCi_PRKCI_ST	Q4VCS5	AMOT	P41743	PRKCI	S538	S538L	538	Missense	central	0	yes	8.288	0.000	EPSD;PhosphoSitePlus	TCGA;COSMIC	6.376	Loss
AGC_PKC_PKCi_PRKCI_ST	Q4VCS5	AMOT	P41743	PRKCI	S538	R534I	534	Missense	distal	-4	no	8.288	7.969	EPSD;PhosphoSitePlus	TCGA;COSMIC;CCLE	6.376	Down-regulation
AGC_PKC_PKCi_PRKCI_ST	Q4VCS5	AMOT	P41743	PRKCI	T750	R747M	747	Missense	distal	-3	no	9.318	7.247	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	6.376	Down-regulation
AGC_PKC_PKCi_PRKCI_ST	Q4VCS5	AMOT	P41743	PRKCI	T750	Q754K	754	Missense	distal	4	no	9.318	9.617	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	6.376	Up-regulation
AGC_PKC_PKCi_PRKCI_ST	Q4VCS5	AMOT	P41743	PRKCI	T750	E745D	745	Missense	distal	-5	no	9.318	7.281	EPSD;PhosphoSitePlus	TCGA;COSMIC	6.376	Down-regulation
AGC_PKC_PKCi_PRKCI_ST	Q4VCS5	AMOT	P41743	PRKCI	T750	I748S	748	Missense	proximal	-2	no	9.318	9.721	EPSD;PhosphoSitePlus	TCGA;ICGC	6.376	Up-regulation
AGC_PKC_PKCi_PRKCI_ST	Q4VCS5	AMOT	P41743	PRKCI	S802	S803F	803	Missense	proximal	1	no	4.729	9.158	EPSD	TCGA;CCLE	6.376	Gain
AGC_PKC_PKCi_PRKCI_ST	Q4VCS5	AMOT	P41743	PRKCI	S855	K856R	856	Missense	proximal	1	no	6.852	3.452	EPSD	TCGA;COSMIC	6.376	Loss
AGC_PKC_PKCi_PRKCI_ST	P08151	GLI1	P41743	PRKCI	S86	I85M	85	Missense	proximal	-1	no	8.494	8.727	EPSD	TCGA;COSMIC	6.376	Up-regulation
AGC_PKC_PKCi_PRKCI_ST	P08151	GLI1	P41743	PRKCI	S86	R81L	81	Missense	distal	-5	no	8.494	5.178	EPSD	TCGA;COSMIC	6.376	Loss
AGC_PKC_PKCi_PRKCI_ST	P08151	GLI1	P41743	PRKCI	S86	S89L	89	Missense	distal	3	no	8.494	9.221	EPSD	TCGA;COSMIC	6.376	Up-regulation
AGC_PKC_PKCi_PRKCI_ST	P08151	GLI1	P41743	PRKCI	S86	S84P	84	Missense	proximal	-2	no	8.494	8.263	EPSD	TCGA;COSMIC	6.376	Down-regulation
AGC_PKC_PKCi_PRKCI_ST	P08151	GLI1	P41743	PRKCI	S86	R81W	81	Missense	distal	-5	no	8.494	3.850	EPSD	TCGA;COSMIC	6.376	Loss
AGC_PKC_PKCi_PRKCI_ST	P08151	GLI1	P41743	PRKCI	S86	R81Q	81	Missense	distal	-5	no	8.494	7.640	EPSD	TCGA;COSMIC	6.376	Down-regulation
AGC_PKC_PKCi_PRKCI_ST	P08151	GLI1	P41743	PRKCI	S86	K79N	79	Missense	distal	-7	no	8.494	8.299	EPSD	TCGA;COSMIC	6.376	Down-regulation
AGC_PKC_PKCi_PRKCI_ST	P08151	GLI1	P41743	PRKCI	S201	S200C	200	Missense	proximal	-1	no	8.249	7.876	EPSD	TCGA;COSMIC	6.376	Down-regulation
AGC_PKC_PKCi_PRKCI_ST	P08151	GLI1	P41743	PRKCI	S201	G197S	197	Missense	distal	-4	no	8.249	8.426	EPSD	TCGA;COSMIC	6.376	Up-regulation
AGC_PKC_PKCi_PRKCI_ST	P08151	GLI1	P41743	PRKCI	S201	G197D	197	Missense	distal	-4	no	8.249	8.222	EPSD	TCGA;COSMIC	6.376	Down-regulation
AGC_PKC_PKCi_PRKCI_ST	P08151	GLI1	P41743	PRKCI	S201	Q208H	208	Missense	distal	7	no	8.249	8.232	EPSD	TCGA;COSMIC	6.376	Down-regulation
AGC_PKC_PKCi_PRKCI_ST	P08151	GLI1	P41743	PRKCI	S243	C242Y	242	Missense	proximal	-1	no	12.133	12.429	EPSD;PhosphoSitePlus	TCGA	6.376	Up-regulation
AGC_PKC_PKCi_PRKCI_ST	P08151	GLI1	P41743	PRKCI	T304	R309W	309	Missense	distal	5	no	10.879	10.369	PhosphoSitePlus;EPSD	TCGA	6.376	Down-regulation
AGC_PKC_PKCi_PRKCI_ST	P08151	GLI1	P41743	PRKCI	T304	R309Q	309	Missense	distal	5	no	10.879	10.865	PhosphoSitePlus;EPSD	TCGA;COSMIC	6.376	Down-regulation
AGC_PKC_PKCi_PRKCI_ST	P08151	GLI1	P41743	PRKCI	S377	S378L	378	Missense	proximal	1	no	4.504	6.837	EPSD	TCGA;COSMIC	6.376	Gain
AGC_PKC_PKCi_PRKCI_ST	P08151	GLI1	P41743	PRKCI	S937	V936A	936	Missense	proximal	-1	no	6.947	7.251	EPSD	TCGA;COSMIC	6.376	Up-regulation
AGC_PKC_PKCi_PRKCI_ST	P08151	GLI1	P41743	PRKCI	S937	L931M	931	Missense	distal	-6	no	6.947	6.492	EPSD	TCGA;COSMIC	6.376	Down-regulation
AGC_PKC_PKCi_PRKCI_ST	P08151	GLI1	P41743	PRKCI	S937	R940H	940	Missense	distal	3	no	6.947	7.342	EPSD	TCGA;GDSC;CCLE	6.376	Up-regulation
AGC_PKC_PKCi_PRKCI_ST	P10636	MAPT	P41743	PRKCI	T50	P47S	47	Missense	distal	-3	no	5.549	7.817	EPSD	TCGA;ICGC;COSMIC	6.376	Gain
AGC_PKC_PKCi_PRKCI_ST	P10636	MAPT	P41743	PRKCI	T71	A77V	77	Missense	distal	6	no	7.912	7.715	EPSD	TCGA;ICGC	6.376	Down-regulation
AGC_PKC_PKCi_PRKCI_ST	P10636	MAPT	P41743	PRKCI	T71	A72V	72	Missense	proximal	1	no	7.912	7.193	EPSD	TCGA;ICGC;COSMIC	6.376	Down-regulation
AGC_PKC_PKCi_PRKCI_ST	P10636	MAPT	P41743	PRKCI	T71	A66S	66	Missense	distal	-5	no	7.912	8.255	EPSD	TCGA;ICGC;COSMIC	6.376	Up-regulation
AGC_PKC_PKCi_PRKCI_ST	P10636	MAPT	P41743	PRKCI	T123	E117K	117	Missense	distal	-6	no	8.172	7.827	EPSD	TCGA;ICGC;COSMIC	6.376	Down-regulation
AGC_PKC_PKCi_PRKCI_ST	P10636	MAPT	P41743	PRKCI	T123	A118V	118	Missense	distal	-5	no	8.172	6.693	EPSD	TCGA;ICGC;COSMIC	6.376	Down-regulation
AGC_PKC_PKCi_PRKCI_ST	P10636	MAPT	P41743	PRKCI	S214	P212L	212	Missense	proximal	-2	no	10.639	10.444	EPSD	TCGA;ICGC;COSMIC	6.376	Down-regulation
AGC_PKC_PKCi_PRKCI_ST	P10636	MAPT	P41743	PRKCI	S214	E220K	220	Missense	distal	6	no	10.639	10.675	EPSD	TCGA;ICGC;COSMIC	6.376	Up-regulation
AGC_PKC_PKCi_PRKCI_ST	P10636	MAPT	P41743	PRKCI	S341	E348V	348	Missense	distal	7	no	6.535	6.423	EPSD	TCGA;ICGC;COSMIC	6.376	Down-regulation
AGC_PKC_PKCi_PRKCI_ST	P10636	MAPT	P41743	PRKCI	S341	G339R	339	Missense	proximal	-2	no	6.535	7.177	EPSD	TCGA;ICGC;COSMIC	6.376	Up-regulation
AGC_PKC_PKCi_PRKCI_ST	P10636	MAPT	P41743	PRKCI	S341	S341F	341	Missense	central	0	yes	6.535	0.000	EPSD	TCGA;ICGC;COSMIC	6.376	Loss
AGC_PKC_PKCi_PRKCI_ST	P10636	MAPT	P41743	PRKCI	T416	P415L	415	Missense	proximal	-1	no	7.632	7.589	EPSD	TCGA;ICGC;COSMIC	6.376	Down-regulation
AGC_PKC_PKCi_PRKCI_ST	P10636	MAPT	P41743	PRKCI	S447	K440E	440	Missense	distal	-7	no	6.735	6.716	EPSD	TCGA;ICGC;COSMIC	6.376	Down-regulation
AGC_PKC_PKCi_PRKCI_ST	P10636	MAPT	P41743	PRKCI	S447	S452C	452	Missense	distal	5	no	6.735	6.434	EPSD	TCGA;ICGC;COSMIC	6.376	Down-regulation
AGC_PKC_PKCi_PRKCI_ST	P10636	MAPT	P41743	PRKCI	S447	S443F	443	Missense	distal	-4	no	6.735	6.355	EPSD	TCGA;ICGC;COSMIC	6.376	Loss
AGC_PKC_PKCi_PRKCI_ST	P10636	MAPT	P41743	PRKCI	S447	S444F	444	Missense	distal	-3	no	6.735	4.324	EPSD	TCGA;ICGC	6.376	Loss
AGC_PKC_PKCi_PRKCI_ST	P10636	MAPT	P41743	PRKCI	S447	S452Y	452	Missense	distal	5	no	6.735	6.769	EPSD	TCGA;ICGC;COSMIC	6.376	Up-regulation
AGC_PKC_PKCi_PRKCI_ST	P10636	MAPT	P41743	PRKCI	T466	R472Q	472	Missense	distal	6	no	6.801	6.715	EPSD	TCGA	6.376	Down-regulation
AGC_PKC_PKCi_PRKCI_ST	P10636	MAPT	P41743	PRKCI	T466	R472W	472	Missense	distal	6	no	6.801	6.369	EPSD	TCGA;COSMIC	6.376	Loss
AGC_PKC_PKCi_PRKCI_ST	P10636	MAPT	P41743	PRKCI	T466	L459R	459	Missense	distal	-7	no	6.801	5.654	EPSD	TCGA;ICGC;COSMIC	6.376	Loss
AGC_PKC_PKCi_PRKCI_ST	P10636	MAPT	P41743	PRKCI	T466	L459F	459	Missense	distal	-7	no	6.801	6.574	EPSD	TCGA;ICGC	6.376	Down-regulation
AGC_PKC_PKCi_PRKCI_ST	P10636	MAPT	P41743	PRKCI	T470	R472Q	472	Missense	proximal	2	no	9.903	9.255	EPSD	TCGA	6.376	Down-regulation
AGC_PKC_PKCi_PRKCI_ST	P10636	MAPT	P41743	PRKCI	T470	R472W	472	Missense	proximal	2	no	9.903	6.638	EPSD	TCGA;COSMIC	6.376	Down-regulation
AGC_PKC_PKCi_PRKCI_ST	Q13464	ROCK1	P41743	PRKCI	S6	R10Q	10	Missense	distal	4	no	11.443	11.609	EPSD	TCGA;ICGC;COSMIC	6.376	Up-regulation
AGC_PKC_PKCi_PRKCI_ST	Q13464	ROCK1	P41743	PRKCI	T9	R10Q	10	Missense	proximal	1	no	6.448	8.458	EPSD	TCGA;ICGC;COSMIC	6.376	Up-regulation
AGC_PKC_PKCi_PRKCI_ST	Q13464	ROCK1	P41743	PRKCI	T298	N295K	295	Missense	distal	-3	no	7.857	8.666	EPSD	TCGA;ICGC;COSMIC	6.376	Up-regulation
AGC_PKC_PKCi_PRKCI_ST	Q13464	ROCK1	P41743	PRKCI	S533	E538K	538	Missense	distal	5	no	6.128	6.414	EPSD	TCGA;ICGC;COSMIC	6.376	Gain
AGC_PKC_PKCi_PRKCI_ST	Q13464	ROCK1	P41743	PRKCI	S633	S633C	633	Missense	central	0	yes	12.099	0.000	EPSD	TCGA;ICGC;COSMIC	6.376	Loss
AGC_PKC_PKCi_PRKCI_ST	Q13464	ROCK1	P41743	PRKCI	S633	R630Q	630	Missense	distal	-3	no	12.099	10.421	EPSD	TCGA;ICGC;COSMIC;GDSC;CCLE	6.376	Down-regulation
AGC_PKC_PKCi_PRKCI_ST	Q13464	ROCK1	P41743	PRKCI	T887	L892F	892	Missense	distal	5	no	8.702	8.810	EPSD	TCGA;ICGC;COSMIC	6.376	Up-regulation
AGC_PKC_PKCi_PRKCI_ST	Q13464	ROCK1	P41743	PRKCI	T887	E886A	886	Missense	proximal	-1	no	8.702	8.731	EPSD	TCGA;ICGC;COSMIC	6.376	Up-regulation
AGC_PKC_PKCi_PRKCI_ST	Q13464	ROCK1	P41743	PRKCI	T890	L892F	892	Missense	proximal	2	no	7.158	6.480	EPSD	TCGA;ICGC;COSMIC	6.376	Down-regulation
AGC_PKC_PKCi_PRKCI_ST	Q13464	ROCK1	P41743	PRKCI	T890	E886A	886	Missense	distal	-4	no	7.158	7.236	EPSD	TCGA;ICGC;COSMIC	6.376	Up-regulation
AGC_PKC_PKCi_PRKCI_ST	Q13464	ROCK1	P41743	PRKCI	T1024	R1019G	1019	Missense	distal	-5	no	8.876	5.420	EPSD;PhosphoSitePlus	TCGA;GDSC;CCLE	6.376	Loss
AGC_PKC_PKCi_PRKCI_ST	Q13464	ROCK1	P41743	PRKCI	T1024	D1026Y	1026	Missense	proximal	2	no	8.876	8.770	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	6.376	Down-regulation
AGC_PKC_PKCi_PRKCI_ST	Q13464	ROCK1	P41743	PRKCI	T1180	H1175Q	1175	Missense	distal	-5	no	9.370	10.446	EPSD	TCGA;ICGC;COSMIC	6.376	Up-regulation
AGC_PKC_PKCi_PRKCI_ST	Q13464	ROCK1	P41743	PRKCI	T1180	P1178S	1178	Missense	proximal	-2	no	9.370	9.601	EPSD	TCGA;ICGC;COSMIC	6.376	Up-regulation
AGC_PKC_PKCi_PRKCI_ST	Q13464	ROCK1	P41743	PRKCI	T1331	R1330Q	1330	Missense	proximal	-1	no	6.613	6.373	EPSD	TCGA;ICGC;COSMIC	6.376	Loss
AGC_PKC_PKCi_PRKCI_ST	Q13464	ROCK1	P41743	PRKCI	S1333	R1330Q	1330	Missense	distal	-3	no	6.478	4.801	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	6.376	Loss
AGC_PKC_PKCi_PRKCI_ST	Q13464	ROCK1	P41743	PRKCI	S1341	R1343W	1343	Missense	proximal	2	no	8.401	5.137	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	6.376	Loss
AGC_PKC_PKCi_PRKCI_ST	Q13464	ROCK1	P41743	PRKCI	S1341	K1347N	1347	Missense	distal	6	no	8.401	8.285	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	6.376	Down-regulation
AGC_PKC_PKCi_PRKCI_ST	Q13464	ROCK1	P41743	PRKCI	S1341	V1346L	1346	Missense	distal	5	no	8.401	8.693	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	6.376	Up-regulation
AGC_PKC_PKCi_PRKCI_ST	Q92934	BAD	P41743	PRKCI	S17	E19D	19	Missense	proximal	2	no	6.885	5.477	EPSD	TCGA;ICGC;COSMIC	6.376	Loss
AGC_PKC_PKCi_PRKCI_ST	Q92934	BAD	P41743	PRKCI	S25	E19D	19	Missense	distal	-6	no	8.959	9.095	EPSD	TCGA;ICGC;COSMIC	6.376	Up-regulation
AGC_PKC_PKCi_PRKCI_ST	Q92934	BAD	P41743	PRKCI	S25	S25N	25	Missense	central	0	yes	8.959	0.000	EPSD	TCGA	6.376	Loss
AGC_PKC_PKCi_PRKCI_ST	Q92934	BAD	P41743	PRKCI	S75	S71I	71	Missense	distal	-4	no	9.961	9.629	PhosphoSitePlus;EPSD	TCGA;ICGC;COSMIC	6.376	Down-regulation
AGC_PKC_PKCi_PRKCI_ST	Q92934	BAD	P41743	PRKCI	S99	A100T	100	Missense	proximal	1	no	9.931	9.055	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	6.376	Down-regulation
AGC_PKC_PKCi_PRKCI_ST	Q92934	BAD	P41743	PRKCI	S118	M117I	117	Missense	proximal	-1	no	7.851	7.617	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	6.376	Down-regulation
AGC_PKC_PKCi_PRKCI_ST	Q13118	KLF10	P41743	PRKCI	T66	V60L	60	Missense	distal	-6	no	6.320	6.491	EPSD	TCGA;COSMIC	6.376	Gain
AGC_PKC_PKCi_PRKCI_ST	Q13118	KLF10	P41743	PRKCI	T66	P64H	64	Missense	proximal	-2	no	6.320	6.657	EPSD	TCGA;COSMIC	6.376	Gain
AGC_PKC_PKCi_PRKCI_ST	Q13118	KLF10	P41743	PRKCI	S328	S329L	329	Missense	proximal	1	no	4.284	6.617	EPSD	TCGA;COSMIC	6.376	Gain
AGC_PKC_PKCi_PRKCI_ST	Q13118	KLF10	P41743	PRKCI	S342	N337S	337	Missense	distal	-5	no	8.185	8.352	EPSD	TCGA;COSMIC	6.376	Up-regulation
AGC_PKC_PKCi_PRKCI_ST	Q13118	KLF10	P41743	PRKCI	S342	P348L	348	Missense	distal	6	no	8.185	8.228	EPSD	TCGA;ICGC;COSMIC	6.376	Up-regulation
AGC_PKC_PKCi_PRKCI_ST	Q13118	KLF10	P41743	PRKCI	S342	G338D	338	Missense	distal	-4	no	8.185	8.158	EPSD	TCGA;COSMIC	6.376	Down-regulation
AGC_PKC_PKCi_PRKCI_ST	Q13118	KLF10	P41743	PRKCI	S342	S335N	335	Missense	distal	-7	no	8.185	8.282	EPSD	TCGA;COSMIC	6.376	Up-regulation
AGC_PKC_PKCi_PRKCI_ST	Q13118	KLF10	P41743	PRKCI	T422	R418K	418	Missense	distal	-4	no	8.101	7.965	EPSD	TCGA;COSMIC	6.376	Down-regulation
AGC_PKC_PKCi_PRKCI_ST	Q13118	KLF10	P41743	PRKCI	T422	L416V	416	Missense	distal	-6	no	8.101	7.929	EPSD	TCGA	6.376	Down-regulation
AGC_PKC_PKCi_PRKCI_ST	Q13118	KLF10	P41743	PRKCI	T422	T424M	424	Missense	proximal	2	no	8.101	7.527	EPSD	TCGA;COSMIC	6.376	Down-regulation
AGC_PKC_PKCi_PRKCI_ST	Q13118	KLF10	P41743	PRKCI	T445	R450C	450	Missense	distal	5	no	9.688	9.028	EPSD;PhosphoSitePlus	TCGA;COSMIC	6.376	Down-regulation
AGC_PKC_PKCi_PRKCI_ST	Q13118	KLF10	P41743	PRKCI	T445	A448V	448	Missense	distal	3	no	9.688	9.944	EPSD;PhosphoSitePlus	TCGA;COSMIC	6.376	Up-regulation
AGC_PKC_PKCi_PRKCI_ST	Q13118	KLF10	P41743	PRKCI	T445	R450H	450	Missense	distal	5	no	9.688	9.561	EPSD;PhosphoSitePlus	TCGA;COSMIC	6.376	Down-regulation
AGC_PKC_PKCi_PRKCI_ST	P15311	EZR	P41743	PRKCI	S249	S249F	249	Missense	central	0	yes	9.309	0.000	EPSD	TCGA;ICGC;COSMIC	6.376	Loss
AGC_PKC_PKCi_PRKCI_ST	P15311	EZR	P41743	PRKCI	T299	I300M	300	Missense	proximal	1	no	6.868	7.972	EPSD	TCGA;ICGC;COSMIC	6.376	Up-regulation
AGC_PKC_PKCi_PRKCI_ST	P15311	EZR	P41743	PRKCI	T299	P297L	297	Missense	proximal	-2	no	6.868	6.673	EPSD	TCGA;ICGC;COSMIC	6.376	Down-regulation
AGC_PKC_PKCi_PRKCI_ST	P15311	EZR	P41743	PRKCI	T299	E301D	301	Missense	proximal	2	no	6.868	5.460	EPSD	TCGA;ICGC	6.376	Loss
AGC_PKC_PKCi_PRKCI_ST	P15311	EZR	P41743	PRKCI	T299	D298G	298	Missense	proximal	-1	no	6.868	6.783	EPSD	TCGA;ICGC	6.376	Down-regulation
AGC_PKC_PKCi_PRKCI_ST	P15311	EZR	P41743	PRKCI	T358	K359N	359	Missense	proximal	1	no	8.091	3.539	EPSD	TCGA;ICGC;COSMIC	6.376	Loss
AGC_PKC_PKCi_PRKCI_ST	P15311	EZR	P41743	PRKCI	T358	D353N	353	Missense	distal	-5	no	8.091	8.790	EPSD	TCGA;ICGC;COSMIC	6.376	Up-regulation
AGC_PKC_PKCi_PRKCI_ST	P15311	EZR	P41743	PRKCI	T358	E362K	362	Missense	distal	4	no	8.091	8.210	EPSD	TCGA;ICGC;COSMIC	6.376	Up-regulation
AGC_PKC_PKCi_PRKCI_ST	P15311	EZR	P41743	PRKCI	T358	E364D	364	Missense	distal	6	no	8.091	7.919	EPSD	TCGA;ICGC	6.376	Down-regulation
AGC_PKC_PKCi_PRKCI_ST	P15311	EZR	P41743	PRKCI	T567	R562Q	562	Missense	distal	-5	no	11.891	11.037	PhosphoSitePlus	TCGA;ICGC	6.376	Down-regulation
AGC_PKC_PKCi_PRKCI_ST	P15311	EZR	P41743	PRKCI	T567	R569Q	569	Missense	proximal	2	no	11.891	11.243	PhosphoSitePlus	TCGA;ICGC;COSMIC	6.376	Down-regulation
AGC_PKC_PKCi_PRKCI_ST	Q15910	EZH2	P41743	PRKCI	S8	K6M	6	Missense	proximal	-2	no	9.834	9.516	EPSD	TCGA;ICGC;COSMIC	6.376	Down-regulation
AGC_PKC_PKCi_PRKCI_ST	Q15910	EZH2	P41743	PRKCI	S8	T4I	4	Missense	distal	-4	no	9.834	9.673	EPSD	TCGA;ICGC;COSMIC	6.376	Down-regulation
AGC_PKC_PKCi_PRKCI_ST	Q15910	EZH2	P41743	PRKCI	S8	T4P	4	Missense	distal	-4	no	9.834	9.677	EPSD	TCGA;ICGC;COSMIC	6.376	Down-regulation
AGC_PKC_PKCi_PRKCI_ST	Q15910	EZH2	P41743	PRKCI	S21	R18C	18	Missense	distal	-3	no	11.389	7.317	EPSD	TCGA;ICGC;COSMIC	6.376	Down-regulation
AGC_PKC_PKCi_PRKCI_ST	Q15910	EZH2	P41743	PRKCI	S21	Q28H	28	Missense	distal	7	no	11.389	11.372	EPSD	TCGA;ICGC	6.376	Down-regulation
AGC_PKC_PKCi_PRKCI_ST	Q15910	EZH2	P41743	PRKCI	S21	R25Q	25	Missense	distal	4	no	11.389	11.556	EPSD	TCGA;ICGC;COSMIC	6.376	Up-regulation
AGC_PKC_PKCi_PRKCI_ST	P08047	SP1	P41743	PRKCI	S7	D5Y	5	Missense	proximal	-2	no	7.903	7.965	EPSD	TCGA;ICGC;COSMIC	6.376	Up-regulation
AGC_PKC_PKCi_PRKCI_ST	P08047	SP1	P41743	PRKCI	S7	A13T	13	Missense	distal	6	no	7.903	7.927	EPSD	TCGA;ICGC;COSMIC	6.376	Up-regulation
AGC_PKC_PKCi_PRKCI_ST	P08047	SP1	P41743	PRKCI	S56	S59F	59	Missense	distal	3	no	6.243	7.071	EPSD	TCGA;ICGC;COSMIC	6.376	Gain
AGC_PKC_PKCi_PRKCI_ST	P08047	SP1	P41743	PRKCI	S59	L61V	61	Missense	proximal	2	no	12.403	11.755	PhosphoSitePlus	TCGA;ICGC;COSMIC	6.376	Down-regulation
AGC_PKC_PKCi_PRKCI_ST	P08047	SP1	P41743	PRKCI	S59	S59F	59	Missense	central	0	yes	12.403	0.000	PhosphoSitePlus	TCGA;ICGC;COSMIC	6.376	Loss
AGC_PKC_PKCi_PRKCI_ST	P08047	SP1	P41743	PRKCI	S73	C68R	68	Missense	distal	-5	no	5.404	10.434	EPSD	TCGA;ICGC;COSMIC	6.376	Gain
AGC_PKC_PKCi_PRKCI_ST	P08047	SP1	P41743	PRKCI	S81	P74S	74	Missense	distal	-7	no	6.769	6.206	EPSD	TCGA;ICGC;COSMIC	6.376	Loss
AGC_PKC_PKCi_PRKCI_ST	P08047	SP1	P41743	PRKCI	S81	S78N	78	Missense	distal	-3	no	6.769	5.599	EPSD	TCGA;ICGC;COSMIC	6.376	Loss
AGC_PKC_PKCi_PRKCI_ST	P08047	SP1	P41743	PRKCI	T679	H676L	676	Missense	distal	-3	no	8.519	7.464	EPSD	TCGA;ICGC;COSMIC	6.376	Down-regulation
AGC_PKC_PKCi_PRKCI_ST	P08047	SP1	P41743	PRKCI	S702	R697K	697	Missense	distal	-5	no	11.514	10.342	EPSD	TCGA;ICGC;COSMIC	6.376	Down-regulation
AGC_PKC_PKCi_PRKCI_ST	Q14247	CTTN	P41743	PRKCI	S33	E34K	34	Missense	proximal	1	no	5.913	9.575	EPSD	TCGA;ICGC;COSMIC	6.376	Gain
AGC_PKC_PKCi_PRKCI_ST	Q14247	CTTN	P41743	PRKCI	S109	Y104C	104	Missense	distal	-5	no	7.813	5.897	EPSD	TCGA;ICGC;COSMIC	6.376	Loss
AGC_PKC_PKCi_PRKCI_ST	Q14247	CTTN	P41743	PRKCI	S109	E103Q	103	Missense	distal	-6	no	7.813	7.020	EPSD	TCGA;ICGC	6.376	Down-regulation
AGC_PKC_PKCi_PRKCI_ST	Q14247	CTTN	P41743	PRKCI	S109	Q114P	114	Missense	distal	5	no	7.813	7.489	EPSD	TCGA;ICGC;COSMIC	6.376	Down-regulation
AGC_PKC_PKCi_PRKCI_ST	Q14247	CTTN	P41743	PRKCI	S109	S113L	113	Missense	distal	4	no	7.813	8.067	EPSD	TCGA;ICGC;COSMIC;GDSC;CCLE	6.376	Up-regulation
AGC_PKC_PKCi_PRKCI_ST	Q14247	CTTN	P41743	PRKCI	S113	G120V	120	Missense	distal	7	no	6.589	6.520	EPSD	TCGA;ICGC;COSMIC	6.376	Down-regulation
AGC_PKC_PKCi_PRKCI_ST	Q14247	CTTN	P41743	PRKCI	S113	Q114P	114	Missense	proximal	1	no	6.589	6.537	EPSD	TCGA;ICGC;COSMIC	6.376	Down-regulation
AGC_PKC_PKCi_PRKCI_ST	Q14247	CTTN	P41743	PRKCI	S113	S113L	113	Missense	central	0	yes	6.589	0.000	EPSD	TCGA;ICGC;COSMIC;GDSC;CCLE	6.376	Loss
AGC_PKC_PKCi_PRKCI_ST	Q14247	CTTN	P41743	PRKCI	T145	E146G	146	Missense	proximal	1	no	7.911	5.957	EPSD	TCGA;ICGC;COSMIC	6.376	Loss
AGC_PKC_PKCi_PRKCI_ST	Q14247	CTTN	P41743	PRKCI	T145	G143R	143	Missense	proximal	-2	no	7.911	8.553	EPSD	TCGA;ICGC;COSMIC	6.376	Up-regulation
AGC_PKC_PKCi_PRKCI_ST	Q14247	CTTN	P41743	PRKCI	S150	E146G	146	Missense	distal	-4	no	11.991	11.891	EPSD	TCGA;ICGC;COSMIC	6.376	Down-regulation
AGC_PKC_PKCi_PRKCI_ST	Q14247	CTTN	P41743	PRKCI	S150	S155F	155	Missense	distal	5	no	11.991	12.185	EPSD	TCGA;ICGC;COSMIC	6.376	Up-regulation
AGC_PKC_PKCi_PRKCI_ST	Q14247	CTTN	P41743	PRKCI	S150	G143R	143	Missense	distal	-7	no	11.991	10.769	EPSD	TCGA;ICGC;COSMIC	6.376	Down-regulation
AGC_PKC_PKCi_PRKCI_ST	Q14247	CTTN	P41743	PRKCI	T182	D177E	177	Missense	distal	-5	no	5.652	7.689	EPSD	TCGA;ICGC;COSMIC	6.376	Gain
AGC_PKC_PKCi_PRKCI_ST	Q14247	CTTN	P41743	PRKCI	S187	R189K	189	Missense	proximal	2	no	13.989	13.122	EPSD	TCGA;ICGC;COSMIC	6.376	Down-regulation
AGC_PKC_PKCi_PRKCI_ST	Q14247	CTTN	P41743	PRKCI	S187	S192F	192	Missense	distal	5	no	13.989	14.184	EPSD	TCGA;ICGC;COSMIC	6.376	Up-regulation
AGC_PKC_PKCi_PRKCI_ST	Q14247	CTTN	P41743	PRKCI	S187	H185L	185	Missense	proximal	-2	no	13.989	13.457	EPSD	TCGA;ICGC;COSMIC	6.376	Down-regulation
AGC_PKC_PKCi_PRKCI_ST	Q14247	CTTN	P41743	PRKCI	S192	R189K	189	Missense	distal	-3	no	6.786	5.369	EPSD	TCGA;ICGC;COSMIC	6.376	Loss
AGC_PKC_PKCi_PRKCI_ST	Q14247	CTTN	P41743	PRKCI	S192	S192F	192	Missense	central	0	yes	6.786	0.000	EPSD	TCGA;ICGC;COSMIC	6.376	Loss
AGC_PKC_PKCi_PRKCI_ST	Q14247	CTTN	P41743	PRKCI	S192	H185L	185	Missense	distal	-7	no	6.786	7.400	EPSD	TCGA;ICGC;COSMIC	6.376	Up-regulation
AGC_PKC_PKCi_PRKCI_ST	Q14247	CTTN	P41743	PRKCI	S224	H222R	222	Missense	proximal	-2	no	8.299	8.683	EPSD	TCGA;ICGC;COSMIC	6.376	Up-regulation
AGC_PKC_PKCi_PRKCI_ST	Q14247	CTTN	P41743	PRKCI	S224	T219M	219	Missense	distal	-5	no	8.299	7.122	EPSD	TCGA;ICGC;COSMIC	6.376	Down-regulation
AGC_PKC_PKCi_PRKCI_ST	Q14247	CTTN	P41743	PRKCI	S261	L256M	256	Missense	distal	-5	no	10.502	11.008	PhosphoSitePlus	TCGA;ICGC;COSMIC	6.376	Up-regulation
AGC_PKC_PKCi_PRKCI_ST	Q14247	CTTN	P41743	PRKCI	S277	K272R	272	Missense	distal	-5	no	5.532	6.704	EPSD	TCGA;COSMIC	6.376	Gain
AGC_PKC_PKCi_PRKCI_ST	Q14247	CTTN	P41743	PRKCI	S282	A284V	284	Missense	proximal	2	no	6.776	5.729	EPSD	TCGA;COSMIC;CCLE	6.376	Loss
AGC_PKC_PKCi_PRKCI_ST	P49757	NUMB	P41743	PRKCI	S194	R196P	196	Missense	proximal	2	no	7.063	4.723	EPSD	TCGA;ICGC;COSMIC	6.376	Loss
AGC_PKC_PKCi_PRKCI_ST	P49757	NUMB	P41743	PRKCI	S194	T201S	201	Missense	distal	7	no	7.063	7.094	EPSD	TCGA;ICGC;COSMIC	6.376	Up-regulation
AGC_PKC_PKCi_PRKCI_ST	P49757	NUMB	P41743	PRKCI	S194	R196G	196	Missense	proximal	2	no	7.063	5.120	EPSD	TCGA;ICGC;COSMIC	6.376	Loss
AGC_PKC_PKCi_PRKCI_ST	P49757	NUMB	P41743	PRKCI	S194	S194L	194	Missense	central	0	yes	7.063	0.000	EPSD	TCGA;ICGC	6.376	Loss
AGC_PKC_PKCi_PRKCI_ST	P49757	NUMB	P41743	PRKCI	S194	R196C	196	Missense	proximal	2	no	7.063	3.469	EPSD	TCGA;ICGC;COSMIC	6.376	Loss
AGC_PKC_PKCi_PRKCI_ST	P49757	NUMB	P41743	PRKCI	T201	S194L	194	Missense	distal	-7	no	6.061	6.838	EPSD	TCGA;ICGC	6.376	Gain
AGC_PKC_PKCi_PRKCI_ST	P49757	NUMB	P41743	PRKCI	S276	F277L	277	Missense	proximal	1	no	8.385	6.290	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	6.376	Loss
AGC_PKC_PKCi_PRKCI_ST	P49757	NUMB	P41743	PRKCI	S276	Q270E	270	Missense	distal	-6	no	8.385	9.178	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	6.376	Up-regulation
AGC_PKC_PKCi_PRKCI_ST	P49757	NUMB	P41743	PRKCI	S627	K626Q	626	Missense	proximal	-1	no	12.310	12.263	EPSD	TCGA;COSMIC	6.376	Down-regulation
AGC_PKC_PKCi_PRKCI_ST	P49757	NUMB	P41743	PRKCI	S627	S627F	627	Missense	central	0	yes	12.310	0.000	EPSD	TCGA;COSMIC	6.376	Loss
AGC_PKC_PKCi_PRKCI_ST	P49757	NUMB	P41743	PRKCI	S627	R630H	630	Missense	distal	3	no	12.310	12.705	EPSD	TCGA;COSMIC;GDSC	6.376	Up-regulation
AGC_PKC_PKCi_PRKCI_ST	P49757	NUMB	P41743	PRKCI	S634	S627F	627	Missense	distal	-7	no	7.373	7.923	EPSD	TCGA;COSMIC	6.376	Up-regulation
AGC_PKC_PKCi_PRKCI_ST	P49757	NUMB	P41743	PRKCI	S634	R630H	630	Missense	distal	-4	no	7.373	7.278	EPSD	TCGA;COSMIC;GDSC	6.376	Down-regulation
AGC_PKC_PKCi_PRKCI_ST	Q9UBS0	RPS6KB2	P41743	PRKCI	S379	A380T	380	Missense	proximal	1	no	6.505	5.629	EPSD	TCGA;ICGC;COSMIC	6.376	Loss
AGC_PKC_PKCi_PRKCI_ST	Q9UBS0	RPS6KB2	P41743	PRKCI	S379	A383G	383	Missense	distal	4	no	6.505	6.875	EPSD	TCGA;ICGC;COSMIC	6.376	Up-regulation
AGC_PKC_PKCi_PRKCI_ST	Q9UBS0	RPS6KB2	P41743	PRKCI	S403	S410L	410	Missense	distal	7	no	7.823	7.672	EPSD	TCGA;ICGC;COSMIC	6.376	Down-regulation
AGC_PKC_PKCi_PRKCI_ST	Q9UBS0	RPS6KB2	P41743	PRKCI	S410	S410L	410	Missense	central	0	yes	6.987	0.000	EPSD	TCGA;ICGC;COSMIC	6.376	Loss
AGC_PKC_PKCi_PRKCI_ST	Q9UBS0	RPS6KB2	P41743	PRKCI	S417	R419W	419	Missense	proximal	2	no	7.655	4.391	EPSD	TCGA;ICGC;COSMIC	6.376	Loss
AGC_PKC_PKCi_PRKCI_ST	Q9UBS0	RPS6KB2	P41743	PRKCI	S417	S410L	410	Missense	distal	-7	no	7.655	8.432	EPSD	TCGA;ICGC;COSMIC	6.376	Up-regulation
AGC_PKC_PKCi_PRKCI_ST	Q6STE5	SMARCD3	P41743	PRKCI	S247	R249H	249	Missense	proximal	2	no	11.235	10.316	PhosphoSitePlus	TCGA;COSMIC	6.376	Down-regulation
AGC_PKC_PKCi_PRKCI_ST	Q6STE5	SMARCD3	P41743	PRKCI	S247	R242W	242	Missense	distal	-5	no	11.235	6.592	PhosphoSitePlus	TCGA;COSMIC	6.376	Down-regulation
AGC_PKC_PKCi_PRKCI_ST	P27448	MARK3	P41743	PRKCI	S400	Q406H	406	Missense	distal	6	no	6.466	6.347	EPSD	TCGA;ICGC;COSMIC	6.376	Loss
AGC_PKC_PKCi_PRKCI_ST	P27448	MARK3	P41743	PRKCI	S400	H403Q	403	Missense	distal	3	no	6.466	6.256	EPSD	TCGA;ICGC;COSMIC	6.376	Loss
AGC_PKC_PKCi_PRKCI_ST	P27448	MARK3	P41743	PRKCI	S400	G398D	398	Missense	proximal	-2	no	6.466	6.453	EPSD	TCGA;ICGC;COSMIC	6.376	Down-regulation
AGC_PKC_PKCi_PRKCI_ST	P27448	MARK3	P41743	PRKCI	T564	P569L	569	Missense	distal	5	no	9.207	9.273	PhosphoSitePlus	TCGA;ICGC;COSMIC	6.376	Up-regulation
AGC_PKC_PKCi_PRKCI_ST	P27448	MARK3	P41743	PRKCI	T564	R570Q	570	Missense	distal	6	no	9.207	9.120	PhosphoSitePlus	TCGA;ICGC;COSMIC	6.376	Down-regulation
AGC_PKC_PKCi_PRKCI_ST	P27448	MARK3	P41743	PRKCI	T564	T559N	559	Missense	distal	-5	no	9.207	8.182	PhosphoSitePlus	TCGA;ICGC	6.376	Down-regulation
AGC_PKC_PKCi_PRKCI_ST	P27448	MARK3	P41743	PRKCI	T576	A575T	575	Missense	proximal	-1	no	7.161	7.168	EPSD	TCGA;ICGC;COSMIC	6.376	Up-regulation
AGC_PKC_PKCi_PRKCI_ST	P27448	MARK3	P41743	PRKCI	T576	P569L	569	Missense	distal	-7	no	7.161	7.375	EPSD	TCGA;ICGC;COSMIC	6.376	Up-regulation
AGC_PKC_PKCi_PRKCI_ST	P27448	MARK3	P41743	PRKCI	T576	R570Q	570	Missense	distal	-6	no	7.161	7.356	EPSD	TCGA;ICGC;COSMIC	6.376	Up-regulation
AGC_PKC_PKCi_PRKCI_ST	P27448	MARK3	P41743	PRKCI	T576	P580H	580	Missense	distal	4	no	7.161	7.083	EPSD	TCGA;ICGC	6.376	Down-regulation
AGC_PKC_PKCi_PRKCI_ST	P27448	MARK3	P41743	PRKCI	S618	T613I	613	Missense	distal	-5	no	12.221	9.505	EPSD	TCGA;ICGC;COSMIC	6.376	Down-regulation
AGC_PKC_PKCi_PRKCI_ST	P27448	MARK3	P41743	PRKCI	S724	C718Y	718	Missense	distal	-6	no	8.174	7.668	EPSD	TCGA;COSMIC	6.376	Down-regulation
AGC_PKC_PKCi_PRKCI_ST	P27448	MARK3	P41743	PRKCI	S724	S724A	724	Missense	central	0	yes	8.174	0.000	EPSD	TCGA	6.376	Loss
AGC_PKC_PKCi_PRKCI_ST	P50613	CDK7	P41743	PRKCI	T25	R30T	30	Missense	distal	5	no	7.009	6.806	EPSD	TCGA;ICGC;COSMIC	6.376	Down-regulation
AGC_PKC_PKCi_PRKCI_ST	P50613	CDK7	P41743	PRKCI	T25	K28R	28	Missense	distal	3	no	7.009	6.858	EPSD	TCGA;ICGC;COSMIC	6.376	Down-regulation
AGC_PKC_PKCi_PRKCI_ST	P50613	CDK7	P41743	PRKCI	T25	E20K	20	Missense	distal	-5	no	7.009	7.156	EPSD	TCGA	6.376	Up-regulation
AGC_PKC_PKCi_PRKCI_ST	P50613	CDK7	P41743	PRKCI	T25	D31Y	31	Missense	distal	6	no	7.009	7.047	EPSD	TCGA;ICGC;COSMIC	6.376	Up-regulation
AGC_PKC_PKCi_PRKCI_ST	P50613	CDK7	P41743	PRKCI	S164	A159T	159	Missense	distal	-5	no	5.629	6.829	EPSD	TCGA;COSMIC	6.376	Gain
AGC_PKC_PKCi_PRKCI_ST	P50613	CDK7	P41743	PRKCI	T170	P165R	165	Missense	distal	-5	no	8.583	12.261	PhosphoSitePlus	TCGA;COSMIC	6.376	Up-regulation
AGC_PKC_PKCi_PRKCI_ST	P50613	CDK7	P41743	PRKCI	T170	N166D	166	Missense	distal	-4	no	8.583	8.277	PhosphoSitePlus	TCGA;COSMIC	6.376	Down-regulation
AGC_PKC_PKCi_PRKCI_ST	Q969H0	FBXW7	P41743	PRKCI	S10	R14Q	14	Missense	distal	4	no	9.953	10.120	PhosphoSitePlus;EPSD	TCGA;ICGC;COSMIC;GDSC;CCLE	6.376	Up-regulation
AGC_PKC_PKCi_PRKCI_ST	Q969H0	FBXW7	P41743	PRKCI	S10	V8L	8	Missense	proximal	-2	no	9.953	9.880	PhosphoSitePlus;EPSD	TCGA;ICGC;COSMIC	6.376	Down-regulation
AGC_PKC_PKCi_PRKCI_ST	Q969H0	FBXW7	P41743	PRKCI	S10	G9S	9	Missense	proximal	-1	no	9.953	10.166	PhosphoSitePlus;EPSD	TCGA;ICGC;COSMIC	6.376	Up-regulation
AGC_PKC_PKCi_PRKCI_ST	Q969H0	FBXW7	P41743	PRKCI	S10	V8M	8	Missense	proximal	-2	no	9.953	10.194	PhosphoSitePlus;EPSD	TCGA;ICGC;COSMIC	6.376	Up-regulation
AGC_PKC_PKCi_PRKCI_ST	Q969H0	FBXW7	P41743	PRKCI	S18	R14Q	14	Missense	distal	-4	no	9.121	9.041	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC;GDSC;CCLE	6.376	Down-regulation
AGC_PKC_PKCi_PRKCI_ST	Q969H0	FBXW7	P41743	PRKCI	S372	G368E	368	Missense	distal	-4	no	8.204	8.304	EPSD	TCGA;ICGC;COSMIC	6.376	Up-regulation
AGC_PKC_PKCi_PRKCI_ST	Q969H0	FBXW7	P41743	PRKCI	S372	K374Q	374	Missense	proximal	2	no	8.204	8.423	EPSD	TCGA	6.376	Up-regulation
AGC_PKC_PKCi_PRKCI_ST	Q969H0	FBXW7	P41743	PRKCI	S372	W365S	365	Missense	distal	-7	no	8.204	7.223	EPSD	TCGA;ICGC;COSMIC	6.376	Down-regulation
AGC_PKC_PKCi_PRKCI_ST	Q969H0	FBXW7	P41743	PRKCI	S372	P373S	373	Missense	proximal	1	no	8.204	5.156	EPSD	TCGA;ICGC;COSMIC	6.376	Loss
AGC_PKC_PKCi_PRKCI_ST	Q969H0	FBXW7	P41743	PRKCI	T680	R674W	674	Missense	distal	-6	no	7.320	8.470	EPSD	TCGA;ICGC;COSMIC	6.376	Up-regulation
AGC_PKC_PKCi_PRKCI_ST	Q969H0	FBXW7	P41743	PRKCI	T680	N679S	679	Missense	proximal	-1	no	7.320	7.465	EPSD	TCGA;ICGC;COSMIC	6.376	Up-regulation
AGC_PKC_PKCi_PRKCI_ST	Q969H0	FBXW7	P41743	PRKCI	T680	R674Q	674	Missense	distal	-6	no	7.320	7.515	EPSD	TCGA;ICGC;COSMIC	6.376	Up-regulation
AGC_PKC_PKCi_PRKCI_ST	Q969H0	FBXW7	P41743	PRKCI	T695	R689W	689	Missense	distal	-6	no	5.380	6.530	EPSD	TCGA;ICGC;COSMIC;GDSC;CCLE	6.376	Gain
AGC_PKC_PKCi_PRKCI_ST	Q8TEW0	PARD3	P41743	PRKCI	S187	Q182E	182	Missense	distal	-5	no	9.421	8.956	EPSD	TCGA;ICGC;COSMIC	6.376	Down-regulation
AGC_PKC_PKCi_PRKCI_ST	Q8TEW0	PARD3	P41743	PRKCI	S187	D192N	192	Missense	distal	5	no	9.421	9.466	EPSD	TCGA;ICGC;COSMIC	6.376	Up-regulation
AGC_PKC_PKCi_PRKCI_ST	Q8TEW0	PARD3	P41743	PRKCI	S386	R392K	392	Missense	distal	6	no	8.859	8.713	EPSD	TCGA;ICGC;COSMIC	6.376	Down-regulation
AGC_PKC_PKCi_PRKCI_ST	Q8TEW0	PARD3	P41743	PRKCI	S386	S386I	386	Missense	central	0	yes	8.859	0.000	EPSD	TCGA;ICGC;COSMIC	6.376	Loss
AGC_PKC_PKCi_PRKCI_ST	Q8TEW0	PARD3	P41743	PRKCI	S386	N391S	391	Missense	distal	5	no	8.859	8.901	EPSD	TCGA;ICGC	6.376	Up-regulation
AGC_PKC_PKCi_PRKCI_ST	Q8TEW0	PARD3	P41743	PRKCI	T453	Y451H	451	Missense	proximal	-2	no	9.219	9.427	EPSD	TCGA;ICGC;COSMIC	6.376	Up-regulation
AGC_PKC_PKCi_PRKCI_ST	Q8TEW0	PARD3	P41743	PRKCI	T453	G457C	457	Missense	distal	4	no	9.219	9.445	EPSD	TCGA;ICGC;COSMIC	6.376	Up-regulation
AGC_PKC_PKCi_PRKCI_ST	Q8TEW0	PARD3	P41743	PRKCI	T453	Y451C	451	Missense	proximal	-2	no	9.219	8.659	EPSD	TCGA;ICGC;COSMIC	6.376	Down-regulation
AGC_PKC_PKCi_PRKCI_ST	Q8TEW0	PARD3	P41743	PRKCI	T468	Q463H	463	Missense	distal	-5	no	7.257	6.182	EPSD	TCGA;ICGC;COSMIC	6.376	Loss
AGC_PKC_PKCi_PRKCI_ST	Q8TEW0	PARD3	P41743	PRKCI	T468	L464R	464	Missense	distal	-4	no	7.257	7.516	EPSD	TCGA;ICGC;COSMIC	6.376	Up-regulation
AGC_PKC_PKCi_PRKCI_ST	Q8TEW0	PARD3	P41743	PRKCI	T468	I462S	462	Missense	distal	-6	no	7.257	6.403	EPSD	TCGA;ICGC	6.376	Down-regulation
AGC_PKC_PKCi_PRKCI_ST	Q8TEW0	PARD3	P41743	PRKCI	S523	G516V	516	Missense	distal	-7	no	7.727	7.682	EPSD	TCGA;ICGC;COSMIC	6.376	Down-regulation
AGC_PKC_PKCi_PRKCI_ST	Q8TEW0	PARD3	P41743	PRKCI	S523	S529L	529	Missense	distal	6	no	7.727	7.621	EPSD	TCGA;ICGC;COSMIC;GDSC;CCLE	6.376	Down-regulation
AGC_PKC_PKCi_PRKCI_ST	Q8TEW0	PARD3	P41743	PRKCI	S529	S529L	529	Missense	central	0	yes	7.752	0.000	EPSD	TCGA;ICGC;COSMIC;GDSC;CCLE	6.376	Loss
AGC_PKC_PKCi_PRKCI_ST	Q8TEW0	PARD3	P41743	PRKCI	T661	S667C	667	Missense	distal	6	no	7.614	7.308	EPSD	TCGA;ICGC;COSMIC	6.376	Down-regulation
AGC_PKC_PKCi_PRKCI_ST	Q8TEW0	PARD3	P41743	PRKCI	T661	D657Y	657	Missense	distal	-4	no	7.614	7.536	EPSD	TCGA;ICGC	6.376	Down-regulation
AGC_PKC_PKCi_PRKCI_ST	Q8TEW0	PARD3	P41743	PRKCI	T668	S667C	667	Missense	proximal	-1	no	8.256	7.883	EPSD	TCGA;ICGC;COSMIC	6.376	Down-regulation
AGC_PKC_PKCi_PRKCI_ST	Q8TEW0	PARD3	P41743	PRKCI	S730	A733D	733	Missense	distal	3	no	6.460	6.626	EPSD	TCGA;ICGC	6.376	Up-regulation
AGC_PKC_PKCi_PRKCI_ST	Q8TEW0	PARD3	P41743	PRKCI	S827	R820Q	820	Missense	distal	-7	no	7.362	7.692	PhosphoSitePlus	TCGA;COSMIC	6.376	Up-regulation
AGC_PKC_PKCi_PRKCI_ST	Q8TEW0	PARD3	P41743	PRKCI	S827	E821V	821	Missense	distal	-6	no	7.362	7.309	PhosphoSitePlus	TCGA;COSMIC	6.376	Down-regulation
AGC_PKC_PKCi_PRKCI_ST	Q8TEW0	PARD3	P41743	PRKCI	S827	R832H	832	Missense	distal	5	no	7.362	7.236	PhosphoSitePlus	TCGA;COSMIC	6.376	Down-regulation
AGC_PKC_PKCi_PRKCI_ST	Q8TEW0	PARD3	P41743	PRKCI	S827	R825C	825	Missense	proximal	-2	no	7.362	6.210	PhosphoSitePlus	TCGA	6.376	Loss
AGC_PKC_PKCi_PRKCI_ST	Q8TEW0	PARD3	P41743	PRKCI	S827	G824E	824	Missense	distal	-3	no	7.362	7.751	PhosphoSitePlus	TCGA	6.376	Up-regulation
AGC_PKC_PKCi_PRKCI_ST	Q8TEW0	PARD3	P41743	PRKCI	S829	G824E	824	Missense	distal	-5	no	5.674	7.812	EPSD	TCGA	6.376	Gain
AGC_PKC_PKCi_PRKCI_ST	Q8TEW0	PARD3	P41743	PRKCI	S852	G856S	856	Missense	distal	4	no	8.007	7.661	EPSD	TCGA;COSMIC	6.376	Down-regulation
AGC_PKC_PKCi_PRKCI_ST	Q8TEW0	PARD3	P41743	PRKCI	S852	K849T	849	Missense	distal	-3	no	8.007	8.175	EPSD	TCGA;COSMIC	6.376	Up-regulation
AGC_PKC_PKCi_PRKCI_ST	Q8TEW0	PARD3	P41743	PRKCI	S889	A896T	896	Missense	distal	7	no	10.239	10.240	EPSD	TCGA;COSMIC	6.376	Up-regulation
AGC_PKC_PKCi_PRKCI_ST	Q8TEW0	PARD3	P41743	PRKCI	S889	K885N	885	Missense	distal	-4	no	10.239	10.490	EPSD	TCGA	6.376	Up-regulation
AGC_PKC_PKCi_PRKCI_ST	Q8TEW0	PARD3	P41743	PRKCI	T901	L902F	902	Missense	proximal	1	no	7.048	9.143	EPSD	TCGA;COSMIC	6.376	Up-regulation
AGC_PKC_PKCi_PRKCI_ST	Q8TEW0	PARD3	P41743	PRKCI	T901	P907S	907	Missense	distal	6	no	7.048	7.197	EPSD	TCGA;COSMIC	6.376	Up-regulation
AGC_PKC_PKCi_PRKCI_ST	Q8TEW0	PARD3	P41743	PRKCI	T901	A896T	896	Missense	distal	-5	no	7.048	8.248	EPSD	TCGA;COSMIC	6.376	Up-regulation
AGC_PKC_PKCi_PRKCI_ST	Q8TEW0	PARD3	P41743	PRKCI	S924	R917S	917	Missense	distal	-7	no	7.329	7.699	EPSD	TCGA;COSMIC	6.376	Up-regulation
AGC_PKC_PKCi_PRKCI_ST	Q8TEW0	PARD3	P41743	PRKCI	S924	D930N	930	Missense	distal	6	no	7.329	7.420	EPSD	TCGA;COSMIC	6.376	Up-regulation
AGC_PKC_PKCi_PRKCI_ST	Q8TEW0	PARD3	P41743	PRKCI	T952	E953K	953	Missense	proximal	1	no	3.265	6.928	EPSD	TCGA	6.376	Gain
AGC_PKC_PKCi_PRKCI_ST	Q8TEW0	PARD3	P41743	PRKCI	T965	S962Y	962	Missense	distal	-3	no	12.389	10.901	EPSD	TCGA	6.376	Down-regulation
AGC_PKC_PKCi_PRKCI_ST	Q8TEW0	PARD3	P41743	PRKCI	S1116	M1123T	1123	Missense	distal	7	no	8.175	8.215	EPSD	TCGA;COSMIC	6.376	Up-regulation
AGC_PKC_PKCi_PRKCI_ST	Q8TEW0	PARD3	P41743	PRKCI	S1116	L1110I	1110	Missense	distal	-6	no	8.175	8.109	EPSD	TCGA;COSMIC	6.376	Down-regulation
AGC_PKC_PKCi_PRKCI_ST	Q8TEW0	PARD3	P41743	PRKCI	S1178	Q1181E	1181	Missense	distal	3	no	11.586	11.637	EPSD	TCGA;COSMIC	6.376	Up-regulation
AGC_PKC_PKCi_PRKCI_ST	Q8TEW0	PARD3	P41743	PRKCI	S1178	R1173C	1173	Missense	distal	-5	no	11.586	6.556	EPSD	TCGA;COSMIC	6.376	Down-regulation
AGC_PKC_PKCi_PRKCI_ST	Q8TEW0	PARD3	P41743	PRKCI	S1178	E1180Q	1180	Missense	proximal	2	no	11.586	11.681	EPSD	TCGA;COSMIC	6.376	Up-regulation
AGC_PKC_PKCi_PRKCI_ST	Q8TEW0	PARD3	P41743	PRKCI	S1178	E1180D	1180	Missense	proximal	2	no	11.586	10.178	EPSD	TCGA;COSMIC	6.376	Down-regulation
AGC_PKC_PKCi_PRKCI_ST	Q8TEW0	PARD3	P41743	PRKCI	S1178	N1185K	1185	Missense	distal	7	no	11.586	11.558	EPSD	TCGA	6.376	Down-regulation
AGC_PKC_PKCi_PRKCI_ST	Q8TEW0	PARD3	P41743	PRKCI	S1178	R1175W	1175	Missense	distal	-3	no	11.586	7.972	EPSD	TCGA;COSMIC	6.376	Down-regulation
AGC_PKC_PKCi_PRKCI_ST	Q8TEW0	PARD3	P41743	PRKCI	S1178	P1184L	1184	Missense	distal	6	no	11.586	11.630	EPSD	TCGA	6.376	Up-regulation
AGC_PKC_PKCi_PRKCI_ST	Q8TEW0	PARD3	P41743	PRKCI	S1178	F1179L	1179	Missense	proximal	1	no	11.586	9.491	EPSD	TCGA	6.376	Down-regulation
AGC_PKC_PKCi_PRKCI_ST	Q8TEW0	PARD3	P41743	PRKCI	S1261	R1258W	1258	Missense	distal	-3	no	8.207	4.593	EPSD	TCGA;COSMIC	6.376	Loss
AGC_PKC_PKCi_PRKCI_ST	Q8TEW0	PARD3	P41743	PRKCI	S1261	G1268C	1268	Missense	distal	7	no	8.207	8.070	EPSD	TCGA;COSMIC	6.376	Down-regulation
AGC_PKC_PKCi_PRKCI_ST	Q8TEW0	PARD3	P41743	PRKCI	S1261	S1261G	1261	Missense	central	0	yes	8.207	0.000	EPSD	TCGA;COSMIC	6.376	Loss
AGC_PKC_PKCi_PRKCI_ST	P78545	ELF3	P41743	PRKCI	S68	S68L	68	Missense	central	0	yes	9.480	0.000	PhosphoSitePlus	TCGA;ICGC;COSMIC	6.376	Loss
AGC_PKC_PKCi_PRKCI_ST	P78545	ELF3	P41743	PRKCI	S68	F66L	66	Missense	proximal	-2	no	9.480	9.487	PhosphoSitePlus	TCGA;ICGC;COSMIC	6.376	Up-regulation
AGC_PKC_PKCi_PRKCI_ST	P78545	ELF3	P41743	PRKCI	S68	D74V	74	Missense	distal	6	no	9.480	9.411	PhosphoSitePlus	TCGA;ICGC;COSMIC	6.376	Down-regulation
AGC_PKC_PKCi_PRKCI_ST	P78545	ELF3	P41743	PRKCI	S210	S204C	204	Missense	distal	-6	no	5.496	6.711	EPSD	TCGA;ICGC;COSMIC	6.376	Gain
AGC_PKC_PKCi_PRKCI_ST	P78545	ELF3	P41743	PRKCI	S254	R251P	251	Missense	distal	-3	no	8.404	5.079	EPSD	TCGA;ICGC;COSMIC	6.376	Loss
AGC_PKC_PKCi_PRKCI_ST	P78545	ELF3	P41743	PRKCI	S254	K252N	252	Missense	proximal	-2	no	8.404	8.000	EPSD	TCGA;ICGC;COSMIC	6.376	Down-regulation
AGC_PKC_PKCi_PRKCI_ST	P78545	ELF3	P41743	PRKCI	S254	R247Q	247	Missense	distal	-7	no	8.404	8.734	EPSD	TCGA;ICGC;COSMIC	6.376	Up-regulation
AGC_PKC_PKCi_PRKCI_ST	P78545	ELF3	P41743	PRKCI	S254	P250R	250	Missense	distal	-4	no	8.404	8.720	EPSD	TCGA;ICGC;COSMIC	6.376	Up-regulation
AGC_PKC_PKCi_PRKCI_ST	P78545	ELF3	P41743	PRKCI	S254	R251L	251	Missense	distal	-3	no	8.404	5.511	EPSD	TCGA;ICGC;COSMIC	6.376	Loss
AGC_PKC_PKCi_PRKCI_ST	P78545	ELF3	P41743	PRKCI	S254	P250S	250	Missense	distal	-4	no	8.404	8.733	EPSD	TCGA;ICGC	6.376	Up-regulation
AGC_PKC_PKCi_PRKCI_ST	P78545	ELF3	P41743	PRKCI	T325	R331W	331	Missense	distal	6	no	6.495	6.063	EPSD	TCGA;ICGC;COSMIC	6.376	Loss
AGC_PKC_PKCi_PRKCI_ST	P78545	ELF3	P41743	PRKCI	T325	L329P	329	Missense	distal	4	no	6.495	6.302	EPSD	TCGA;ICGC;COSMIC	6.376	Loss
AGC_PKC_PKCi_PRKCI_ST	P78545	ELF3	P41743	PRKCI	T325	M324T	324	Missense	proximal	-1	no	6.495	6.528	EPSD	TCGA;ICGC;COSMIC	6.376	Up-regulation
AGC_PKC_PKCi_PRKCI_ST	P78545	ELF3	P41743	PRKCI	T325	A332V	332	Missense	distal	7	no	6.495	6.363	EPSD	TCGA;ICGC;COSMIC	6.376	Loss
AGC_PKC_PKCi_PRKCI_ST	Q16236	NFE2L2	P41743	PRKCI	S215	P214Q	214	Missense	proximal	-1	no	6.785	6.884	EPSD	TCGA;COSMIC	6.376	Up-regulation
AGC_PKC_PKCi_PRKCI_ST	Q16236	NFE2L2	P41743	PRKCI	S549	S549I	549	Missense	central	0	yes	6.498	0.000	EPSD	TCGA;COSMIC	6.376	Loss
AGC_PKC_PKCi_PRKCI_ST	Q16236	NFE2L2	P41743	PRKCI	T559	E563K	563	Missense	distal	4	no	6.260	6.380	EPSD	TCGA;COSMIC	6.376	Gain
AGC_PKC_PKCi_PRKCI_ST	Q16236	NFE2L2	P41743	PRKCI	S577	P575L	575	Missense	proximal	-2	no	6.486	6.291	EPSD	TCGA;COSMIC	6.376	Loss
AGC_PKC_PKCi_PRKCI_ST	Q16236	NFE2L2	P41743	PRKCI	S577	D570N	570	Missense	distal	-7	no	6.486	5.882	EPSD	TCGA;COSMIC	6.376	Loss
AGC_PKC_PKCi_PRKCI_ST	Q16236	NFE2L2	P41743	PRKCI	S577	P575S	575	Missense	proximal	-2	no	6.486	6.716	EPSD	TCGA;COSMIC	6.376	Up-regulation
AGC_PKC_PKCi_PRKCI_ST	Q9NPB6	PARD6A	P41743	PRKCI	S11	A9V	9	Missense	proximal	-2	no	7.305	7.003	EPSD	TCGA;ICGC;COSMIC	6.376	Down-regulation
AGC_PKC_PKCi_PRKCI_ST	Q9NPB6	PARD6A	P41743	PRKCI	S109	R112W	112	Missense	distal	3	no	5.505	6.463	EPSD	TCGA;COSMIC	6.376	Gain
AGC_PKC_PKCi_PRKCI_ST	Q9H8V3	ECT2	P41743	PRKCI	S24	S19C	19	Missense	distal	-5	no	6.713	4.172	EPSD	TCGA;ICGC;COSMIC	6.376	Loss
AGC_PKC_PKCi_PRKCI_ST	Q9H8V3	ECT2	P41743	PRKCI	S24	E28D	28	Missense	distal	4	no	6.713	6.995	EPSD	TCGA;ICGC;COSMIC	6.376	Up-regulation
AGC_PKC_PKCi_PRKCI_ST	Q9H8V3	ECT2	P41743	PRKCI	T359	E355K	355	Missense	distal	-4	no	8.314	8.242	PhosphoSitePlus	TCGA;COSMIC	6.376	Down-regulation
AGC_PKC_PKCi_PRKCI_ST	Q9H8V3	ECT2	P41743	PRKCI	T359	V366A	366	Missense	distal	7	no	8.314	8.447	PhosphoSitePlus	TCGA;COSMIC	6.376	Up-regulation
AGC_PKC_PKCi_PRKCI_ST	Q9H8V3	ECT2	P41743	PRKCI	T359	P360H	360	Missense	proximal	1	no	8.314	7.171	PhosphoSitePlus	TCGA;COSMIC	6.376	Down-regulation
AGC_PKC_PKCi_PRKCI_ST	Q9H8V3	ECT2	P41743	PRKCI	T359	A357S	357	Missense	proximal	-2	no	8.314	8.364	PhosphoSitePlus	TCGA;COSMIC	6.376	Up-regulation
AGC_PKC_PKCi_PRKCI_ST	Q9H8V3	ECT2	P41743	PRKCI	S443	T444I	444	Missense	proximal	1	no	8.358	9.395	EPSD	TCGA;COSMIC	6.376	Up-regulation
AGC_PKC_PKCi_PRKCI_ST	Q9H8V3	ECT2	P41743	PRKCI	S448	T444I	444	Missense	distal	-4	no	6.742	6.581	EPSD	TCGA;COSMIC	6.376	Down-regulation
AGC_PKC_PKCi_PRKCI_ST	Q9H8V3	ECT2	P41743	PRKCI	S844	T846I	846	Missense	proximal	2	no	10.663	9.359	EPSD	TCGA;COSMIC	6.376	Down-regulation
AGC_PKC_PKCi_PRKCI_ST	Q9H8V3	ECT2	P41743	PRKCI	T905	L906S	906	Missense	proximal	1	no	7.278	4.945	EPSD	TCGA;COSMIC	6.376	Loss
AGC_PKC_PKCi_PRKCI_ST	Q9H8V3	ECT2	P41743	PRKCI	T905	R902I	902	Missense	distal	-3	no	7.278	3.767	EPSD	TCGA;COSMIC	6.376	Loss
AGC_PKC_PKCi_PRKCI_ST	Q9H8V3	ECT2	P41743	PRKCI	T911	L906S	906	Missense	distal	-5	no	7.022	7.849	EPSD	TCGA;COSMIC	6.376	Up-regulation
TK_Syk_ZAP70_Y	P29353	SHC1	P43403	ZAP70	Y349	P354A	354	Missense	distal	5	no	11.718	11.623	EPSD	TCGA;COSMIC	5.220	Down-regulation
TK_Syk_ZAP70_Y	P29353	SHC1	P43403	ZAP70	Y349	F353L	353	Missense	distal	4	no	11.718	11.656	EPSD	TCGA;COSMIC	5.220	Down-regulation
TK_Syk_ZAP70_Y	P29353	SHC1	P43403	ZAP70	Y349	P344S	344	Missense	distal	-5	no	11.718	11.713	EPSD	TCGA;COSMIC	5.220	Down-regulation
TK_Syk_ZAP70_Y	P29353	SHC1	P43403	ZAP70	Y350	P354A	354	Missense	distal	4	no	9.502	9.487	EPSD	TCGA;COSMIC	5.220	Down-regulation
TK_Syk_ZAP70_Y	P29353	SHC1	P43403	ZAP70	Y350	E357K	357	Missense	distal	7	no	9.502	9.580	EPSD	TCGA;COSMIC	5.220	Up-regulation
TK_Syk_ZAP70_Y	P29353	SHC1	P43403	ZAP70	Y350	F353L	353	Missense	distal	3	no	9.502	9.818	EPSD	TCGA;COSMIC	5.220	Up-regulation
TK_Syk_ZAP70_Y	P29353	SHC1	P43403	ZAP70	Y350	P344S	344	Missense	distal	-6	no	9.502	9.391	EPSD	TCGA;COSMIC	5.220	Down-regulation
TK_Syk_ZAP70_Y	Q9UQC2	GAB2	P43403	ZAP70	Y194	R201Q	201	Missense	distal	7	no	6.412	6.421	EPSD	TCGA;COSMIC	5.220	Up-regulation
TK_Syk_ZAP70_Y	Q9UQC2	GAB2	P43403	ZAP70	Y194	E191K	191	Missense	distal	-3	no	6.412	4.479	EPSD	TCGA;COSMIC	5.220	Loss
TK_Syk_ZAP70_Y	Q9UQC2	GAB2	P43403	ZAP70	Y194	A188T	188	Missense	distal	-6	no	6.412	5.836	EPSD	TCGA;COSMIC	5.220	Down-regulation
TK_Syk_ZAP70_Y	Q9UQC2	GAB2	P43403	ZAP70	Y266	R270H	270	Missense	distal	4	no	9.840	9.642	EPSD	TCGA;COSMIC	5.220	Down-regulation
TK_Syk_ZAP70_Y	Q9UQC2	GAB2	P43403	ZAP70	Y266	T265N	265	Missense	proximal	-1	no	9.840	9.916	EPSD	TCGA;COSMIC;CCLE	5.220	Up-regulation
TK_Syk_ZAP70_Y	Q9UQC2	GAB2	P43403	ZAP70	Y266	T265I	265	Missense	proximal	-1	no	9.840	9.722	EPSD	TCGA;COSMIC	5.220	Down-regulation
TK_Syk_ZAP70_Y	Q9UQC2	GAB2	P43403	ZAP70	Y266	F261S	261	Missense	distal	-5	no	9.840	9.823	EPSD	TCGA	5.220	Down-regulation
TK_Syk_ZAP70_Y	Q9UQC2	GAB2	P43403	ZAP70	Y293	T294N	294	Missense	proximal	1	no	7.692	6.917	EPSD	TCGA;COSMIC	5.220	Down-regulation
TK_Syk_ZAP70_Y	Q9UQC2	GAB2	P43403	ZAP70	Y411	E407Q	407	Missense	distal	-4	no	6.326	6.077	EPSD	TCGA;COSMIC	5.220	Down-regulation
TK_Syk_ZAP70_Y	Q9UQC2	GAB2	P43403	ZAP70	Y411	R414G	414	Missense	distal	3	no	6.326	4.759	EPSD	TCGA;COSMIC	5.220	Loss
TK_Syk_ZAP70_Y	Q9UQC2	GAB2	P43403	ZAP70	Y411	S405F	405	Missense	distal	-6	no	6.326	5.423	EPSD	TCGA;COSMIC	5.220	Down-regulation
TK_Syk_ZAP70_Y	Q9UQC2	GAB2	P43403	ZAP70	Y411	R414C	414	Missense	distal	3	no	6.326	5.606	EPSD	TCGA;COSMIC;CCLE	5.220	Down-regulation
TK_Syk_ZAP70_Y	Q9UQC2	GAB2	P43403	ZAP70	Y452	D450N	450	Missense	proximal	-2	no	7.321	7.375	EPSD	TCGA;COSMIC	5.220	Up-regulation
TK_Syk_ZAP70_Y	Q9UQC2	GAB2	P43403	ZAP70	Y452	D450Y	450	Missense	proximal	-2	no	7.321	6.570	EPSD	TCGA;COSMIC	5.220	Down-regulation
TK_Syk_ZAP70_Y	Q9UQC2	GAB2	P43403	ZAP70	Y614	G610S	610	Missense	distal	-4	no	9.402	9.734	PhosphoSitePlus	TCGA;COSMIC;CCLE	5.220	Up-regulation
TK_Syk_ZAP70_Y	Q9UQC2	GAB2	P43403	ZAP70	Y614	P621Q	621	Missense	distal	7	no	9.402	9.439	PhosphoSitePlus	TCGA;COSMIC	5.220	Up-regulation
TK_Syk_ZAP70_Y	Q9UQC2	GAB2	P43403	ZAP70	Y614	A616D	616	Missense	proximal	2	no	9.402	9.013	PhosphoSitePlus	TCGA;COSMIC	5.220	Down-regulation
TK_Syk_ZAP70_Y	P43403	ZAP70	P43403	ZAP70	Y126	R124H	124	Missense	proximal	-2	no	8.864	8.459	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	5.220	Down-regulation
TK_Syk_ZAP70_Y	P43403	ZAP70	P43403	ZAP70	Y126	V127M	127	Missense	proximal	1	no	8.864	8.622	EPSD;PhosphoSitePlus	TCGA;ICGC;CCLE	5.220	Down-regulation
TK_Syk_ZAP70_Y	P43403	ZAP70	P43403	ZAP70	Y126	Q129H	129	Missense	distal	3	no	8.864	8.125	EPSD;PhosphoSitePlus	TCGA;ICGC	5.220	Down-regulation
TK_Syk_ZAP70_Y	P43403	ZAP70	P43403	ZAP70	Y126	R128C	128	Missense	proximal	2	no	8.864	8.569	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	5.220	Down-regulation
TK_Syk_ZAP70_Y	P43403	ZAP70	P43403	ZAP70	Y315	V314M	314	Missense	proximal	-1	no	9.219	9.632	PhosphoSitePlus;EPSD	TCGA;ICGC;COSMIC	5.220	Up-regulation
TK_Syk_ZAP70_Y	P43403	ZAP70	P43403	ZAP70	Y315	D321N	321	Missense	distal	6	no	9.219	9.130	PhosphoSitePlus;EPSD	TCGA;ICGC;COSMIC	5.220	Down-regulation
TK_Syk_ZAP70_Y	P43403	ZAP70	P43403	ZAP70	Y319	E324K	324	Missense	distal	5	no	11.898	11.190	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	5.220	Down-regulation
TK_Syk_ZAP70_Y	P43403	ZAP70	P43403	ZAP70	Y319	V314M	314	Missense	distal	-5	no	11.898	11.890	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	5.220	Down-regulation
TK_Syk_ZAP70_Y	P43403	ZAP70	P43403	ZAP70	Y319	D321N	321	Missense	proximal	2	no	11.898	12.160	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	5.220	Up-regulation
TK_Syk_ZAP70_Y	P43403	ZAP70	P43403	ZAP70	Y357	R358L	358	Missense	proximal	1	no	4.801	6.171	EPSD	TCGA;ICGC;COSMIC	5.220	Gain
TK_Syk_ZAP70_Y	P43403	ZAP70	P43403	ZAP70	Y492	R496H	496	Missense	distal	4	no	8.864	8.666	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	5.220	Down-regulation
TK_Syk_ZAP70_Y	P43403	ZAP70	P43403	ZAP70	Y492	Y492C	492	Missense	central	0	yes	8.864	0.000	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	5.220	Loss
TK_Syk_ZAP70_Y	P43403	ZAP70	P43403	ZAP70	Y492	A485S	485	Missense	distal	-7	no	8.864	8.922	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	5.220	Up-regulation
TK_Syk_ZAP70_Y	P43403	ZAP70	P43403	ZAP70	Y493	R496H	496	Missense	distal	3	no	9.310	7.673	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	5.220	Down-regulation
TK_Syk_ZAP70_Y	P43403	ZAP70	P43403	ZAP70	Y493	Y492C	492	Missense	proximal	-1	no	9.310	9.414	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	5.220	Up-regulation
TK_Syk_ZAP70_Y	P43403	ZAP70	P43403	ZAP70	Y569	E567K	567	Missense	proximal	-2	no	6.328	5.974	EPSD	TCGA;ICGC;COSMIC;GDSC	5.220	Down-regulation
TK_Syk_ZAP70_Y	P43403	ZAP70	P43403	ZAP70	Y597	Q591P	591	Missense	distal	-6	no	4.554	5.480	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	5.220	Gain
TK_Syk_ZAP70_Y	Q13094	LCP2	P43403	ZAP70	Y113	S115R	115	Missense	proximal	2	no	13.540	13.430	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	5.220	Down-regulation
TK_Syk_ZAP70_Y	Q13094	LCP2	P43403	ZAP70	Y113	E109D	109	Missense	distal	-4	no	13.540	13.481	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	5.220	Down-regulation
TK_Syk_ZAP70_Y	Q13094	LCP2	P43403	ZAP70	Y113	D111N	111	Missense	proximal	-2	no	13.540	13.593	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC;GDSC;CCLE	5.220	Up-regulation
TK_Syk_ZAP70_Y	Q13094	LCP2	P43403	ZAP70	Y128	D127N	127	Missense	proximal	-1	no	12.246	12.050	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	5.220	Down-regulation
TK_Syk_ZAP70_Y	Q13094	LCP2	P43403	ZAP70	Y128	E123K	123	Missense	distal	-5	no	12.246	12.268	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	5.220	Up-regulation
TK_Syk_ZAP70_Y	Q13094	LCP2	P43403	ZAP70	Y128	N132S	132	Missense	distal	4	no	12.246	12.196	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	5.220	Down-regulation
TK_Syk_ZAP70_Y	Q13094	LCP2	P43403	ZAP70	Y128	G122V	122	Missense	distal	-6	no	12.246	12.588	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	5.220	Up-regulation
TK_Syk_ZAP70_Y	Q13094	LCP2	P43403	ZAP70	Y145	A143E	143	Missense	proximal	-2	no	13.583	13.262	PhosphoSitePlus;EPSD	TCGA;ICGC	5.220	Down-regulation
TK_Syk_ZAP70_Y	Q13094	LCP2	P43403	ZAP70	Y145	V139M	139	Missense	distal	-6	no	13.583	14.516	PhosphoSitePlus;EPSD	TCGA;ICGC;COSMIC;CCLE	5.220	Up-regulation
TK_Syk_ZAP70_Y	Q13094	LCP2	P43403	ZAP70	Y145	D144E	144	Missense	proximal	-1	no	13.583	13.560	PhosphoSitePlus;EPSD	TCGA;ICGC;COSMIC	5.220	Down-regulation
TK_Syk_ZAP70_Y	Q13094	LCP2	P43403	ZAP70	Y423	W422C	422	Missense	proximal	-1	no	5.129	5.426	EPSD	TCGA;ICGC;COSMIC	5.220	Gain
TK_Syk_ZAP70_Y	Q13094	LCP2	P43403	ZAP70	Y426	W422C	422	Missense	distal	-4	no	5.194	5.417	EPSD	TCGA;ICGC;COSMIC	5.220	Gain
TK_Syk_ZAP70_Y	Q8N1K5	THEMIS	P43403	ZAP70	Y540	M543T	543	Missense	distal	3	no	11.017	8.928	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	5.220	Down-regulation
TK_Syk_ZAP70_Y	Q8N1K5	THEMIS	P43403	ZAP70	Y540	E547K	547	Missense	distal	7	no	11.017	11.096	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	5.220	Up-regulation
TK_Syk_ZAP70_Y	Q8N1K5	THEMIS	P43403	ZAP70	Y540	Q539K	539	Missense	proximal	-1	no	11.017	10.880	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	5.220	Down-regulation
TK_Syk_ZAP70_Y	Q8N1K5	THEMIS	P43403	ZAP70	Y540	R545I	545	Missense	distal	5	no	11.017	10.694	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	5.220	Down-regulation
TK_Syk_ZAP70_Y	Q8N1K5	THEMIS	P43403	ZAP70	Y541	M543T	543	Missense	proximal	2	no	10.532	10.363	PhosphoSitePlus;EPSD	TCGA;ICGC;COSMIC	5.220	Down-regulation
TK_Syk_ZAP70_Y	Q8N1K5	THEMIS	P43403	ZAP70	Y541	E547K	547	Missense	distal	6	no	10.532	10.345	PhosphoSitePlus;EPSD	TCGA;ICGC;COSMIC	5.220	Down-regulation
TK_Syk_ZAP70_Y	Q8N1K5	THEMIS	P43403	ZAP70	Y541	Q539K	539	Missense	proximal	-2	no	10.532	10.286	PhosphoSitePlus;EPSD	TCGA;ICGC;COSMIC	5.220	Down-regulation
TK_Syk_ZAP70_Y	Q8N1K5	THEMIS	P43403	ZAP70	Y541	R545I	545	Missense	distal	4	no	10.532	10.398	PhosphoSitePlus;EPSD	TCGA;ICGC;COSMIC	5.220	Down-regulation
TK_Syk_ZAP70_Y	Q16539	MAPK14	P43403	ZAP70	Y323	D324A	324	Missense	proximal	1	no	11.786	11.028	PhosphoSitePlus	TCGA;COSMIC	5.220	Down-regulation
TK_Syk_ZAP70_Y	P51452	DUSP3	P43403	ZAP70	Y138	A137T	137	Missense	proximal	-1	no	11.685	11.603	PhosphoSitePlus;EPSD	TCGA;ICGC;COSMIC	5.220	Down-regulation
TK_Syk_ZAP70_Y	P51452	DUSP3	P43403	ZAP70	Y138	T133M	133	Missense	distal	-5	no	11.685	11.677	PhosphoSitePlus;EPSD	TCGA;ICGC;COSMIC	5.220	Down-regulation
Atypical_BCR_BCR_ST	P27348	YWHAQ	P11274	BCR	S145	R138G	138	Missense	distal	-7	no	2.028	2.040	EPSD	TCGA;ICGC;COSMIC	1.927	Up-regulation
Atypical_BCR_BCR_ST	P27348	YWHAQ	P11274	BCR	S145	G147E	147	Missense	proximal	2	no	2.028	2.049	EPSD	TCGA;ICGC;COSMIC	1.927	Up-regulation
Atypical_BCR_BCR_ST	P27348	YWHAQ	P11274	BCR	S145	R138Q	138	Missense	distal	-7	no	2.028	2.026	EPSD	TCGA;ICGC;COSMIC	1.927	Down-regulation
Atypical_BCR_BCR_ST	P27348	YWHAQ	P11274	BCR	S145	A152S	152	Missense	distal	7	no	2.028	1.890	EPSD	TCGA;ICGC;COSMIC	1.927	Loss
Atypical_BCR_BCR_ST	P27348	YWHAQ	P11274	BCR	S232	E236V	236	Missense	distal	4	no	17.130	17.113	PhosphoSitePlus	TCGA;ICGC;COSMIC	1.927	Down-regulation
Atypical_BCR_BCR_ST	P63104	YWHAZ	P11274	BCR	S156	E151Q	151	Missense	distal	-5	no	3.782	3.897	EPSD	TCGA;ICGC;COSMIC	1.927	Up-regulation
Atypical_BCR_BCR_ST	P63104	YWHAZ	P11274	BCR	S156	I155T	155	Missense	proximal	-1	no	3.782	3.773	EPSD	TCGA	1.927	Down-regulation
Atypical_BCR_BCR_ST	P63104	YWHAZ	P11274	BCR	T205	S210L	210	Missense	distal	5	no	2.352	2.088	EPSD	TCGA;ICGC;COSMIC	1.927	Down-regulation
Atypical_BCR_BCR_ST	P63104	YWHAZ	P11274	BCR	T205	S207I	207	Missense	proximal	2	no	2.352	2.356	EPSD	TCGA;ICGC;COSMIC	1.927	Up-regulation
Atypical_BCR_BCR_ST	P63104	YWHAZ	P11274	BCR	T205	K212T	212	Missense	distal	7	no	2.352	2.438	EPSD	TCGA;ICGC;COSMIC	1.927	Up-regulation
Atypical_BCR_BCR_ST	P63104	YWHAZ	P11274	BCR	T232	G234R	234	Missense	proximal	2	no	16.666	16.660	PhosphoSitePlus	TCGA;ICGC;COSMIC	1.927	Down-regulation
Atypical_BCR_BCR_ST	P63104	YWHAZ	P11274	BCR	T232	G234A	234	Missense	proximal	2	no	16.666	16.601	PhosphoSitePlus	TCGA;ICGC;COSMIC	1.927	Down-regulation
Atypical_BCR_BCR_ST	P63104	YWHAZ	P11274	BCR	T232	Q233E	233	Missense	proximal	1	no	16.666	16.604	PhosphoSitePlus	TCGA;ICGC;COSMIC	1.927	Down-regulation
Atypical_BCR_BCR_ST	P63104	YWHAZ	P11274	BCR	T232	S230L	230	Missense	proximal	-2	no	16.666	16.582	PhosphoSitePlus	TCGA;ICGC;COSMIC	1.927	Down-regulation
Other_WEE_Myt1_PKMYT1_ST	P06493	CDK1	Q99640	PKMYT1	T14	K9R	9	Missense	distal	-5	no	4.767	4.761	PhosphoSitePlus;EPSD	TCGA;ICGC;COSMIC	1.669	Down-regulation
Other_WEE_Myt1_PKMYT1_ST	P06493	CDK1	Q99640	PKMYT1	S53	E57V	57	Missense	distal	4	no	1.729	2.292	EPSD	TCGA;ICGC;COSMIC	1.669	Up-regulation
Other_WEE_Myt1_PKMYT1_ST	P06493	CDK1	Q99640	PKMYT1	S53	R59C	59	Missense	distal	6	no	1.729	1.728	EPSD	TCGA;ICGC;COSMIC;GDSC	1.669	Down-regulation
Other_WEE_Myt1_PKMYT1_ST	P06493	CDK1	Q99640	PKMYT1	S53	R50W	50	Missense	distal	-3	no	1.729	1.738	EPSD	TCGA;ICGC;COSMIC	1.669	Up-regulation
Other_WEE_Myt1_PKMYT1_ST	P06493	CDK1	Q99640	PKMYT1	S248	P242S	242	Missense	distal	-6	no	1.486	1.692	EPSD	TCGA;ICGC;COSMIC	1.669	Gain
Other_NEK_NEK6_NEK7_ST	Q15058	KIF14	Q8TDX7	NEK7	S56	I63M	63	Missense	distal	7	no	8.347	8.316	PhosphoSitePlus;EPSD	TCGA;ICGC;COSMIC	3.120	Down-regulation
Other_NEK_NEK6_NEK7_ST	Q15058	KIF14	Q8TDX7	NEK7	S56	G58C	58	Missense	proximal	2	no	8.347	8.417	PhosphoSitePlus;EPSD	TCGA;ICGC;COSMIC	3.120	Up-regulation
Other_NEK_NEK6_NEK7_ST	Q15058	KIF14	Q8TDX7	NEK7	S56	P52L	52	Missense	distal	-4	no	8.347	8.431	PhosphoSitePlus;EPSD	TCGA;ICGC;COSMIC	3.120	Up-regulation
Other_NEK_NEK6_NEK7_ST	Q15058	KIF14	Q8TDX7	NEK7	T66	I63M	63	Missense	distal	-3	no	3.221	3.360	EPSD	TCGA;ICGC;COSMIC	3.120	Up-regulation
Other_NEK_NEK6_NEK7_ST	Q15058	KIF14	Q8TDX7	NEK7	T66	Y67N	67	Missense	proximal	1	no	3.221	3.227	EPSD	TCGA;ICGC;COSMIC	3.120	Up-regulation
Other_NEK_NEK6_NEK7_ST	Q15058	KIF14	Q8TDX7	NEK7	T66	R65I	65	Missense	proximal	-1	no	3.221	3.209	EPSD	TCGA;ICGC;COSMIC;CCLE	3.120	Down-regulation
Other_NEK_NEK6_NEK7_ST	Q15058	KIF14	Q8TDX7	NEK7	T81	P82L	82	Missense	proximal	1	no	3.616	3.629	EPSD	TCGA;ICGC;COSMIC	3.120	Up-regulation
Other_NEK_NEK6_NEK7_ST	Q15058	KIF14	Q8TDX7	NEK7	T144	I138R	138	Missense	distal	-6	no	3.211	3.148	EPSD	TCGA	3.120	Down-regulation
Other_NEK_NEK6_NEK7_ST	Q15058	KIF14	Q8TDX7	NEK7	T144	E150G	150	Missense	distal	6	no	3.211	3.281	EPSD	TCGA;ICGC;COSMIC	3.120	Up-regulation
Other_NEK_NEK6_NEK7_ST	Q15058	KIF14	Q8TDX7	NEK7	T144	M143V	143	Missense	proximal	-1	no	3.211	3.216	EPSD	TCGA;ICGC;COSMIC	3.120	Up-regulation
Other_NEK_NEK6_NEK7_ST	Q15058	KIF14	Q8TDX7	NEK7	T144	D139Y	139	Missense	distal	-5	no	3.211	3.138	EPSD	TCGA;ICGC;COSMIC	3.120	Down-regulation
Other_NEK_NEK6_NEK7_ST	Q15058	KIF14	Q8TDX7	NEK7	S201	R205K	205	Missense	distal	4	no	3.957	3.835	EPSD	TCGA;ICGC;COSMIC	3.120	Down-regulation
Other_NEK_NEK6_NEK7_ST	Q15058	KIF14	Q8TDX7	NEK7	S201	K195Q	195	Missense	distal	-6	no	3.957	4.048	EPSD	TCGA;ICGC;COSMIC	3.120	Up-regulation
Other_NEK_NEK6_NEK7_ST	Q15058	KIF14	Q8TDX7	NEK7	T561	K554N	554	Missense	distal	-7	no	2.310	3.182	EPSD	TCGA;ICGC;COSMIC	3.120	Gain
Other_NEK_NEK6_NEK7_ST	Q15058	KIF14	Q8TDX7	NEK7	S568	D565V	565	Missense	distal	-3	no	2.334	3.606	EPSD	TCGA;ICGC;COSMIC	3.120	Gain
Other_NEK_NEK6_NEK7_ST	Q15058	KIF14	Q8TDX7	NEK7	T632	K628R	628	Missense	distal	-4	no	3.875	3.978	EPSD	TCGA;ICGC	3.120	Up-regulation
Other_NEK_NEK6_NEK7_ST	Q15058	KIF14	Q8TDX7	NEK7	S1186	S1190C	1190	Missense	distal	4	no	3.032	3.233	EPSD	TCGA;ICGC;COSMIC	3.120	Gain
Other_NEK_NEK6_NEK7_ST	Q15058	KIF14	Q8TDX7	NEK7	S1217	S1220L	1220	Missense	distal	3	no	7.414	7.417	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	3.120	Up-regulation
Other_NEK_NEK6_NEK7_ST	Q15058	KIF14	Q8TDX7	NEK7	S1217	K1212N	1212	Missense	distal	-5	no	7.414	7.390	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	3.120	Down-regulation
Other_NEK_NEK6_NEK7_ST	Q15058	KIF14	Q8TDX7	NEK7	S1219	S1220L	1220	Missense	proximal	1	no	7.531	7.702	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	3.120	Up-regulation
Other_NEK_NEK6_NEK7_ST	Q15058	KIF14	Q8TDX7	NEK7	S1219	K1212N	1212	Missense	distal	-7	no	7.531	8.403	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	3.120	Up-regulation
Other_NEK_NEK6_NEK7_ST	Q15058	KIF14	Q8TDX7	NEK7	S1220	S1220L	1220	Missense	central	0	yes	7.362	0.000	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	3.120	Loss
Other_NEK_NEK6_NEK7_ST	Q15058	KIF14	Q8TDX7	NEK7	S1466	I1470M	1470	Missense	distal	4	no	3.633	3.666	EPSD	TCGA;ICGC;COSMIC	3.120	Up-regulation
Other_NEK_NEK6_NEK7_ST	Q15058	KIF14	Q8TDX7	NEK7	S1466	R1465I	1465	Missense	proximal	-1	no	3.633	3.622	EPSD	TCGA;ICGC;COSMIC	3.120	Down-regulation
Other_NEK_NEK6_NEK7_ST	P54274	TERF1	Q8TDX7	NEK7	S404	G399V	399	Missense	distal	-5	no	3.291	3.135	EPSD	TCGA;COSMIC	3.120	Down-regulation
Other_NEK_NEK6_NEK7_ST	P52732	KIF11	Q8TDX7	NEK7	S36	R33L	33	Missense	distal	-3	no	4.510	6.017	EPSD	TCGA;ICGC;COSMIC	3.120	Up-regulation
Other_NEK_NEK6_NEK7_ST	P52732	KIF11	Q8TDX7	NEK7	S36	A37T	37	Missense	proximal	1	no	4.510	4.511	EPSD	TCGA;ICGC;COSMIC	3.120	Up-regulation
Other_NEK_NEK6_NEK7_ST	P52732	KIF11	Q8TDX7	NEK7	S936	R940K	940	Missense	distal	4	no	4.870	4.748	EPSD	TCGA;ICGC	3.120	Down-regulation
TK_Tec_TXK_Y	P42681	TXK	P42681	TXK	Y91	P98A	98	Missense	distal	7	no	5.928	5.542	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	1.475	Down-regulation
TK_Tec_TXK_Y	P42681	TXK	P42681	TXK	Y91	P95S	95	Missense	distal	4	no	5.928	5.840	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	1.475	Down-regulation
TK_Tec_TXK_Y	P42681	TXK	P42681	TXK	Y91	P98L	98	Missense	distal	7	no	5.928	5.329	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	1.475	Down-regulation
TK_Tec_TXK_Y	P42681	TXK	P42681	TXK	Y91	D92N	92	Missense	proximal	1	no	5.928	5.767	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	1.475	Down-regulation
TK_Tec_TXK_Y	P42681	TXK	P42681	TXK	Y91	I85F	85	Missense	distal	-6	no	5.928	5.943	EPSD;PhosphoSitePlus	TCGA	1.475	Up-regulation
TK_Tec_TXK_Y	P42681	TXK	P42681	TXK	Y91	A89T	89	Missense	proximal	-2	no	5.928	5.473	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	1.475	Down-regulation
TK_Tec_TXK_Y	P42681	TXK	P42681	TXK	Y420	D418V	418	Missense	proximal	-2	no	5.628	5.313	PhosphoSitePlus;EPSD	TCGA;ICGC;COSMIC	1.475	Down-regulation
TK_Tec_TXK_Y	P42681	TXK	P42681	TXK	Y420	A426D	426	Missense	distal	6	no	5.628	5.643	PhosphoSitePlus;EPSD	TCGA;ICGC;COSMIC	1.475	Up-regulation
TK_Tec_TXK_Y	P42681	TXK	P42681	TXK	Y420	V415I	415	Missense	distal	-5	no	5.628	5.555	PhosphoSitePlus;EPSD	TCGA;ICGC	1.475	Down-regulation
TKL_STKR_STKR1_BMPR1B_ST	Q15796	SMAD2	O00238	BMPR1B	S317	F311L	311	Missense	distal	-6	no	-1.119	-1.121	EPSD	TCGA;ICGC;COSMIC	-1.120	Loss
TKL_STKR_STKR1_BMPR1B_ST	Q15796	SMAD2	O00238	BMPR1B	S317	R321Q	321	Missense	distal	4	no	-1.119	-1.077	EPSD	TCGA;ICGC;COSMIC;GDSC;CCLE	-1.120	Up-regulation
TKL_STKR_STKR1_BMPR1B_ST	Q15796	SMAD2	O00238	BMPR1B	S317	G314A	314	Missense	distal	-3	no	-1.119	-1.118	EPSD	TCGA;ICGC;COSMIC	-1.120	Up-regulation
TKL_STKR_STKR1_BMPR1B_ST	Q15796	SMAD2	O00238	BMPR1B	S317	A323V	323	Missense	distal	6	no	-1.119	-1.206	EPSD	TCGA;ICGC;COSMIC	-1.120	Loss
TKL_STKR_STKR1_BMPR1B_ST	Q15796	SMAD2	O00238	BMPR1B	S417	G421W	421	Missense	distal	4	no	-1.094	-0.992	EPSD	TCGA;ICGC;COSMIC	-1.120	Up-regulation
TKL_STKR_STKR1_BMPR1B_ST	Q15796	SMAD2	O00238	BMPR1B	S417	G421A	421	Missense	distal	4	no	-1.094	-1.003	EPSD	TCGA;ICGC;COSMIC	-1.120	Up-regulation
TKL_STKR_STKR1_BMPR1B_ST	Q15796	SMAD2	O00238	BMPR1B	S417	S417R	417	Missense	central	0	yes	-1.094	0.000	EPSD	TCGA;ICGC	-1.120	Loss
TKL_STKR_STKR1_BMPR1B_ST	Q15796	SMAD2	O00238	BMPR1B	S464	G457A	457	Missense	distal	-7	no	-0.891	-0.915	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	-1.120	Down-regulation
TKL_STKR_STKR1_BMPR1B_ST	Q15797	SMAD1	O00238	BMPR1B	T10	A13T	13	Missense	distal	3	no	-1.075	-1.089	EPSD	TCGA;ICGC;COSMIC	-1.120	Down-regulation
TKL_STKR_STKR1_BMPR1B_ST	Q15797	SMAD1	O00238	BMPR1B	S11	A13T	13	Missense	proximal	2	no	-1.096	-1.094	EPSD	TCGA;ICGC;COSMIC	-1.120	Up-regulation
TKL_STKR_STKR1_BMPR1B_ST	Q15797	SMAD1	O00238	BMPR1B	S462	V464L	464	Missense	proximal	2	no	-0.890	-0.888	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	-1.120	Up-regulation
TKL_STKR_STKR1_BMPR1B_ST	Q15797	SMAD1	O00238	BMPR1B	S463	V464L	464	Missense	proximal	1	no	-0.813	-0.811	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	-1.120	Up-regulation
TKL_STKR_STKR1_BMPR1B_ST	Q15797	SMAD1	O00238	BMPR1B	S465	V464L	464	Missense	proximal	-1	no	-0.836	-0.839	PhosphoSitePlus;EPSD	TCGA;ICGC;COSMIC	-1.120	Down-regulation
TK_Jak_TYK2_Y	P29597	TYK2	P29597	TYK2	Y1054	E1053K	1053	Missense	proximal	-1	no	39.574	39.082	EPSD;PhosphoSitePlus	TCGA;COSMIC	21.015	Down-regulation
TK_Jak_TYK2_Y	P29597	TYK2	P29597	TYK2	Y1054	E1050K	1050	Missense	distal	-4	no	39.574	40.704	EPSD;PhosphoSitePlus	TCGA;COSMIC	21.015	Up-regulation
TK_Jak_TYK2_Y	P29597	TYK2	P29597	TYK2	Y1054	E1059D	1059	Missense	distal	5	no	39.574	37.820	EPSD;PhosphoSitePlus	TCGA;COSMIC	21.015	Down-regulation
TK_Jak_TYK2_Y	P29597	TYK2	P29597	TYK2	Y1054	R1058H	1058	Missense	distal	4	no	39.574	38.666	EPSD;PhosphoSitePlus	TCGA;COSMIC	21.015	Down-regulation
TK_Jak_TYK2_Y	P29597	TYK2	P29597	TYK2	Y1054	P1049S	1049	Missense	distal	-5	no	39.574	39.308	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	21.015	Down-regulation
TK_Jak_TYK2_Y	P29597	TYK2	P29597	TYK2	Y1055	E1053K	1053	Missense	proximal	-2	no	39.028	39.691	EPSD;PhosphoSitePlus	TCGA;COSMIC	21.015	Up-regulation
TK_Jak_TYK2_Y	P29597	TYK2	P29597	TYK2	Y1055	E1050K	1050	Missense	distal	-5	no	39.028	39.268	EPSD;PhosphoSitePlus	TCGA;COSMIC	21.015	Up-regulation
TK_Jak_TYK2_Y	P29597	TYK2	P29597	TYK2	Y1055	E1059D	1059	Missense	distal	4	no	39.028	40.056	EPSD;PhosphoSitePlus	TCGA;COSMIC	21.015	Up-regulation
TK_Jak_TYK2_Y	P29597	TYK2	P29597	TYK2	Y1055	R1058H	1058	Missense	distal	3	no	39.028	39.080	EPSD;PhosphoSitePlus	TCGA;COSMIC	21.015	Up-regulation
TK_Jak_TYK2_Y	P29597	TYK2	P29597	TYK2	Y1055	P1049S	1049	Missense	distal	-6	no	39.028	37.479	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	21.015	Down-regulation
TK_Jak_TYK2_Y	P17181	IFNAR1	P29597	TYK2	Y466	V467A	467	Missense	proximal	1	no	38.990	38.998	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	21.015	Up-regulation
TK_Jak_TYK2_Y	P17181	IFNAR1	P29597	TYK2	Y481	Y481H	481	Missense	central	0	yes	40.008	0.000	PhosphoSitePlus;EPSD	TCGA;COSMIC	21.015	Loss
TK_Jak_TYK2_Y	O15304	SIVA1	P29597	TYK2	Y53	H56Q	56	Missense	distal	3	no	41.028	40.936	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	21.015	Down-regulation
TK_Jak_TYK2_Y	P40763	STAT3	P29597	TYK2	Y640	S636F	636	Missense	distal	-4	no	44.286	39.437	PhosphoSitePlus	TCGA;ICGC;COSMIC	21.015	Down-regulation
TK_Jak_TYK2_Y	P40763	STAT3	P29597	TYK2	Y640	N647I	647	Missense	distal	7	no	44.286	40.777	PhosphoSitePlus	TCGA;ICGC;COSMIC	21.015	Down-regulation
TK_Jak_TYK2_Y	P40763	STAT3	P29597	TYK2	Y640	Q644R	644	Missense	distal	4	no	44.286	43.532	PhosphoSitePlus	TCGA;ICGC	21.015	Down-regulation
TK_Jak_TYK2_Y	P40763	STAT3	P29597	TYK2	Y640	Y640F	640	Missense	central	0	yes	44.286	0.000	PhosphoSitePlus	TCGA;ICGC;COSMIC;GDSC;CCLE	21.015	Loss
TK_Jak_TYK2_Y	P40763	STAT3	P29597	TYK2	Y640	T641I	641	Missense	proximal	1	no	44.286	44.330	PhosphoSitePlus	TCGA;ICGC;COSMIC	21.015	Up-regulation
TK_Jak_TYK2_Y	P40763	STAT3	P29597	TYK2	Y640	P639L	639	Missense	proximal	-1	no	44.286	42.915	PhosphoSitePlus	TCGA;ICGC;COSMIC	21.015	Down-regulation
TK_Jak_TYK2_Y	P40763	STAT3	P29597	TYK2	Y640	E638K	638	Missense	proximal	-2	no	44.286	44.950	PhosphoSitePlus	TCGA;ICGC;COSMIC	21.015	Up-regulation
TK_Jak_TYK2_Y	P40763	STAT3	P29597	TYK2	Y640	K642E	642	Missense	proximal	2	no	44.286	42.632	PhosphoSitePlus	TCGA;ICGC;COSMIC	21.015	Down-regulation
TK_Jak_TYK2_Y	P40763	STAT3	P29597	TYK2	Y640	V637M	637	Missense	distal	-3	no	44.286	44.188	PhosphoSitePlus	TCGA;ICGC;COSMIC	21.015	Down-regulation
TK_Jak_TYK2_Y	P40763	STAT3	P29597	TYK2	Y640	N647S	647	Missense	distal	7	no	44.286	45.556	PhosphoSitePlus	TCGA;ICGC	21.015	Up-regulation
TK_Fak_PTK2B_Y	O15259	NPHP1	Q14289	PTK2B	Y46	C49Y	49	Missense	distal	3	no	510.001	513.190	EPSD;PhosphoSitePlus	TCGA;ICGC	366.093	Up-regulation
TK_Fak_PTK2B_Y	O15259	NPHP1	Q14289	PTK2B	Y46	R48I	48	Missense	proximal	2	no	510.001	506.846	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	366.093	Down-regulation
TK_Fak_PTK2B_Y	O15259	NPHP1	Q14289	PTK2B	Y46	N40D	40	Missense	distal	-6	no	510.001	509.480	EPSD;PhosphoSitePlus	TCGA;ICGC	366.093	Down-regulation
TK_Fak_PTK2B_Y	O15259	NPHP1	Q14289	PTK2B	Y46	R42I	42	Missense	distal	-4	no	510.001	390.600	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	366.093	Down-regulation
TK_Fak_PTK2B_Y	O43294	TGFB1I1	Q14289	PTK2B	Y60	T62M	62	Missense	proximal	2	no	569.681	566.554	PhosphoSitePlus	TCGA;COSMIC;GDSC;CCLE	366.093	Down-regulation
TK_Fak_PTK2B_Y	O43294	TGFB1I1	Q14289	PTK2B	Y60	D55N	55	Missense	distal	-5	no	569.681	567.088	PhosphoSitePlus	TCGA;COSMIC	366.093	Down-regulation
TK_Fak_PTK2B_Y	O43294	TGFB1I1	Q14289	PTK2B	Y60	T62K	62	Missense	proximal	2	no	569.681	567.982	PhosphoSitePlus	TCGA;COSMIC	366.093	Down-regulation
TK_Fak_PTK2B_Y	O43294	TGFB1I1	Q14289	PTK2B	Y60	R67W	67	Missense	distal	7	no	569.681	567.428	PhosphoSitePlus	TCGA;COSMIC	366.093	Down-regulation
TK_Fak_PTK2B_Y	P37840	SNCA	Q14289	PTK2B	Y125	P120S	120	Missense	distal	-5	no	505.058	514.888	PhosphoSitePlus	TCGA;ICGC;COSMIC	366.093	Up-regulation
TK_Fak_PTK2B_Y	P37840	SNCA	Q14289	PTK2B	Y125	S129F	129	Missense	distal	4	no	505.058	472.104	PhosphoSitePlus	TCGA;ICGC;COSMIC	366.093	Down-regulation
TK_Fak_PTK2B_Y	P37840	SNCA	Q14289	PTK2B	Y133	E137K	137	Missense	distal	4	no	429.398	415.102	EPSD	TCGA;ICGC;COSMIC	366.093	Down-regulation
TK_Fak_PTK2B_Y	P37840	SNCA	Q14289	PTK2B	Y133	D135Y	135	Missense	proximal	2	no	429.398	425.814	EPSD	TCGA;ICGC;COSMIC	366.093	Down-regulation
TK_Fak_PTK2B_Y	P37840	SNCA	Q14289	PTK2B	Y133	S129F	129	Missense	distal	-4	no	429.398	297.140	EPSD	TCGA;ICGC;COSMIC	366.093	Loss
TK_Fak_PTK2B_Y	Q14289	PTK2B	Q14289	PTK2B	Y402	I397L	397	Missense	distal	-5	no	715.215	714.643	PhosphoSitePlus	TCGA;ICGC;COSMIC	366.093	Down-regulation
TK_Fak_PTK2B_Y	Q14289	PTK2B	Q14289	PTK2B	Y579	R586H	586	Missense	distal	7	no	391.776	390.559	EPSD	TCGA;COSMIC	366.093	Down-regulation
TK_Fak_PTK2B_Y	Q14289	PTK2B	Q14289	PTK2B	Y579	A582S	582	Missense	distal	3	no	391.776	390.694	EPSD	TCGA	366.093	Down-regulation
TK_Fak_PTK2B_Y	Q14289	PTK2B	Q14289	PTK2B	Y579	R586C	586	Missense	distal	7	no	391.776	390.388	EPSD	TCGA;ICGC;COSMIC	366.093	Down-regulation
TK_Fak_PTK2B_Y	Q14289	PTK2B	Q14289	PTK2B	Y580	R586H	586	Missense	distal	6	no	443.113	442.910	EPSD	TCGA;COSMIC	366.093	Down-regulation
TK_Fak_PTK2B_Y	Q14289	PTK2B	Q14289	PTK2B	Y580	A582S	582	Missense	proximal	2	no	443.113	444.366	EPSD	TCGA	366.093	Up-regulation
TK_Fak_PTK2B_Y	Q14289	PTK2B	Q14289	PTK2B	Y580	R586C	586	Missense	distal	6	no	443.113	442.883	EPSD	TCGA;ICGC;COSMIC	366.093	Down-regulation
TK_Fak_PTK2B_Y	Q14289	PTK2B	Q14289	PTK2B	Y722	P717L	717	Missense	distal	-5	no	441.541	438.258	EPSD	TCGA;ICGC;COSMIC	366.093	Down-regulation
TK_Fak_PTK2B_Y	Q14289	PTK2B	Q14289	PTK2B	Y722	P725S	725	Missense	distal	3	no	441.541	440.463	EPSD	TCGA;COSMIC	366.093	Down-regulation
TK_Fak_PTK2B_Y	Q14289	PTK2B	Q14289	PTK2B	Y722	R723S	723	Missense	proximal	1	no	441.541	443.690	EPSD	TCGA;ICGC;COSMIC	366.093	Up-regulation
TK_Fak_PTK2B_Y	Q05397	PTK2	Q14289	PTK2B	Y194	V201I	201	Missense	distal	7	no	377.688	378.402	EPSD	TCGA;ICGC;COSMIC	366.093	Up-regulation
TK_Fak_PTK2B_Y	Q05397	PTK2	Q14289	PTK2B	Y397	E403K	403	Missense	distal	6	no	496.167	496.079	EPSD	TCGA;ICGC;COSMIC	366.093	Down-regulation
TK_Fak_PTK2B_Y	Q05397	PTK2	Q14289	PTK2B	Y397	D395Y	395	Missense	proximal	-2	no	496.167	422.266	EPSD	TCGA;ICGC	366.093	Down-regulation
TK_Fak_PTK2B_Y	Q05397	PTK2	Q14289	PTK2B	Y397	E404G	404	Missense	distal	7	no	496.167	491.961	EPSD	TCGA;ICGC;COSMIC	366.093	Down-regulation
TK_Fak_PTK2B_Y	Q05397	PTK2	Q14289	PTK2B	Y407	E403K	403	Missense	distal	-4	no	679.931	632.573	PhosphoSitePlus	TCGA;ICGC;COSMIC	366.093	Down-regulation
TK_Fak_PTK2B_Y	Q05397	PTK2	Q14289	PTK2B	Y407	E404G	404	Missense	distal	-3	no	679.931	579.300	PhosphoSitePlus	TCGA;ICGC;COSMIC	366.093	Down-regulation
TK_Fak_PTK2B_Y	Q05397	PTK2	Q14289	PTK2B	Y441	A448T	448	Missense	distal	7	no	421.327	421.882	EPSD	TCGA;ICGC;COSMIC	366.093	Up-regulation
TK_Fak_PTK2B_Y	Q05397	PTK2	Q14289	PTK2B	Y441	V436I	436	Missense	distal	-5	no	421.327	422.746	EPSD	TCGA;ICGC;COSMIC	366.093	Up-regulation
TK_Fak_PTK2B_Y	Q05397	PTK2	Q14289	PTK2B	Y441	A448D	448	Missense	distal	7	no	421.327	423.602	EPSD	TCGA;ICGC;COSMIC	366.093	Up-regulation
TK_Fak_PTK2B_Y	P29474	NOS3	Q14289	PTK2B	Y657	Y657C	657	Missense	central	0	yes	449.011	0.000	PhosphoSitePlus	TCGA;ICGC;COSMIC	366.093	Loss
TK_Fak_PTK2B_Y	P29474	NOS3	Q14289	PTK2B	Y657	A656T	656	Missense	proximal	-1	no	449.011	444.061	PhosphoSitePlus	TCGA	366.093	Down-regulation
TK_Fak_PTK2B_Y	P29474	NOS3	Q14289	PTK2B	Y657	P658T	658	Missense	proximal	1	no	449.011	460.878	PhosphoSitePlus	TCGA;ICGC;COSMIC;GDSC;CCLE	366.093	Up-regulation
TK_Fak_PTK2B_Y	P29474	NOS3	Q14289	PTK2B	Y657	A662T	662	Missense	distal	5	no	449.011	468.652	PhosphoSitePlus	TCGA;ICGC;COSMIC	366.093	Up-regulation
AGC_RSK_RSKp70_RPS6KB2_ST	Q15633	TARBP2	Q9UBS0	RPS6KB2	S283	S286C	286	Missense	distal	3	no	10.205	10.299	PhosphoSitePlus	TCGA;COSMIC	4.103	Up-regulation
AGC_RSK_RSKp70_RPS6KB2_ST	P04792	HSPB1	Q9UBS0	RPS6KB2	S15	L10H	10	Missense	distal	-5	no	5.741	5.792	EPSD	TCGA;ICGC;COSMIC	4.103	Up-regulation
AGC_RSK_RSKp70_RPS6KB2_ST	P04792	HSPB1	Q9UBS0	RPS6KB2	S78	L81I	81	Missense	distal	3	no	10.348	10.385	PhosphoSitePlus;EPSD	TCGA;ICGC;COSMIC	4.103	Up-regulation
AGC_RSK_RSKp70_RPS6KB2_ST	P04792	HSPB1	Q9UBS0	RPS6KB2	S82	L81I	81	Missense	proximal	-1	no	9.866	8.753	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	4.103	Down-regulation
AGC_RSK_RSKp70_RPS6KB2_ST	P04792	HSPB1	Q9UBS0	RPS6KB2	T139	F138C	138	Missense	proximal	-1	no	6.546	7.602	EPSD	TCGA;ICGC;COSMIC	4.103	Up-regulation
AGC_RSK_RSKp70_RPS6KB2_ST	P04792	HSPB1	Q9UBS0	RPS6KB2	T143	F138C	138	Missense	distal	-5	no	6.518	6.573	EPSD	TCGA;ICGC;COSMIC	4.103	Up-regulation
AGC_RSK_RSKp70_RPS6KB2_ST	P04792	HSPB1	Q9UBS0	RPS6KB2	T174	I179N	179	Missense	distal	5	no	4.127	4.120	EPSD	TCGA;ICGC;COSMIC	4.103	Down-regulation
AGC_RSK_RSKp70_RPS6KB2_ST	P04792	HSPB1	Q9UBS0	RPS6KB2	T174	K171N	171	Missense	distal	-3	no	4.127	1.613	EPSD	TCGA;ICGC;COSMIC	4.103	Loss
AGC_RSK_RSKp70_RPS6KB2_ST	P49841	GSK3B	Q9UBS0	RPS6KB2	S35	G34S	34	Missense	proximal	-1	no	3.952	5.144	EPSD	TCGA;COSMIC	4.103	Gain
AGC_RSK_RSKp70_RPS6KB2_ST	P49841	GSK3B	Q9UBS0	RPS6KB2	S147	R148G	148	Missense	proximal	1	no	5.899	6.149	EPSD	TCGA;ICGC;COSMIC	4.103	Up-regulation
AGC_RSK_RSKp70_RPS6KB2_ST	P05783	KRT18	Q9UBS0	RPS6KB2	S30	P28L	28	Missense	proximal	-2	no	5.083	5.724	EPSD	TCGA;ICGC;COSMIC	4.103	Up-regulation
AGC_RSK_RSKp70_RPS6KB2_ST	P05783	KRT18	Q9UBS0	RPS6KB2	S53	G57D	57	Missense	distal	4	no	9.837	9.942	PhosphoSitePlus	TCGA;ICGC;COSMIC	4.103	Up-regulation
AGC_RSK_RSKp70_RPS6KB2_ST	P05783	KRT18	Q9UBS0	RPS6KB2	S53	S60Y	60	Missense	distal	7	no	9.837	9.833	PhosphoSitePlus	TCGA;ICGC;COSMIC	4.103	Down-regulation
AGC_RSK_RSKp70_RPS6KB2_ST	P05783	KRT18	Q9UBS0	RPS6KB2	S127	P121S	121	Missense	distal	-6	no	6.467	6.318	EPSD	TCGA;ICGC;COSMIC	4.103	Down-regulation
AGC_RSK_RSKp70_RPS6KB2_ST	P05783	KRT18	Q9UBS0	RPS6KB2	S127	G120E	120	Missense	distal	-7	no	6.467	6.456	EPSD	TCGA	4.103	Down-regulation
AGC_RSK_RSKp70_RPS6KB2_ST	O00418	EEF2K	Q9UBS0	RPS6KB2	S61	E67K	67	Missense	distal	6	no	4.142	4.164	EPSD	TCGA;ICGC;COSMIC	4.103	Up-regulation
AGC_RSK_RSKp70_RPS6KB2_ST	O00418	EEF2K	Q9UBS0	RPS6KB2	S61	S61G	61	Missense	central	0	yes	4.142	0.000	EPSD	TCGA;ICGC	4.103	Loss
AGC_RSK_RSKp70_RPS6KB2_ST	O00418	EEF2K	Q9UBS0	RPS6KB2	S61	R68W	68	Missense	distal	7	no	4.142	4.140	EPSD	TCGA	4.103	Down-regulation
AGC_RSK_RSKp70_RPS6KB2_ST	O00418	EEF2K	Q9UBS0	RPS6KB2	S61	S61I	61	Missense	central	0	yes	4.142	0.000	EPSD	TCGA;ICGC	4.103	Loss
AGC_RSK_RSKp70_RPS6KB2_ST	O00418	EEF2K	Q9UBS0	RPS6KB2	S71	E67K	67	Missense	distal	-4	no	5.698	5.843	EPSD	TCGA;ICGC;COSMIC	4.103	Up-regulation
AGC_RSK_RSKp70_RPS6KB2_ST	O00418	EEF2K	Q9UBS0	RPS6KB2	S71	R68W	68	Missense	distal	-3	no	5.698	0.879	EPSD	TCGA	4.103	Loss
AGC_RSK_RSKp70_RPS6KB2_ST	O00418	EEF2K	Q9UBS0	RPS6KB2	S71	S74C	74	Missense	distal	3	no	5.698	5.792	EPSD	TCGA;ICGC;COSMIC	4.103	Up-regulation
AGC_RSK_RSKp70_RPS6KB2_ST	O00418	EEF2K	Q9UBS0	RPS6KB2	S135	K132Q	132	Missense	distal	-3	no	4.366	2.303	EPSD	TCGA;ICGC;COSMIC	4.103	Loss
AGC_RSK_RSKp70_RPS6KB2_ST	O00418	EEF2K	Q9UBS0	RPS6KB2	S135	R140Q	140	Missense	distal	5	no	4.366	4.348	EPSD	TCGA;ICGC;COSMIC	4.103	Down-regulation
AGC_RSK_RSKp70_RPS6KB2_ST	O00418	EEF2K	Q9UBS0	RPS6KB2	S135	I131M	131	Missense	distal	-4	no	4.366	4.421	EPSD	TCGA;ICGC;COSMIC	4.103	Up-regulation
AGC_RSK_RSKp70_RPS6KB2_ST	O00418	EEF2K	Q9UBS0	RPS6KB2	S135	G141R	141	Missense	distal	6	no	4.366	4.239	EPSD	TCGA;ICGC;COSMIC	4.103	Down-regulation
AGC_RSK_RSKp70_RPS6KB2_ST	O00418	EEF2K	Q9UBS0	RPS6KB2	S241	N240S	240	Missense	proximal	-1	no	3.951	4.735	EPSD	TCGA;ICGC;COSMIC	4.103	Gain
AGC_RSK_RSKp70_RPS6KB2_ST	O00418	EEF2K	Q9UBS0	RPS6KB2	S243	N240S	240	Missense	distal	-3	no	4.356	4.766	EPSD	TCGA;ICGC;COSMIC	4.103	Up-regulation
AGC_RSK_RSKp70_RPS6KB2_ST	O00418	EEF2K	Q9UBS0	RPS6KB2	S366	S366F	366	Missense	central	0	yes	9.928	0.000	PhosphoSitePlus	TCGA;ICGC;COSMIC	4.103	Loss
AGC_RSK_RSKp70_RPS6KB2_ST	O00418	EEF2K	Q9UBS0	RPS6KB2	S366	S366C	366	Missense	central	0	yes	9.928	0.000	PhosphoSitePlus	TCGA;ICGC;COSMIC	4.103	Loss
AGC_RSK_RSKp70_RPS6KB2_ST	O00418	EEF2K	Q9UBS0	RPS6KB2	S366	P371S	371	Missense	distal	5	no	9.928	9.835	PhosphoSitePlus	TCGA;ICGC;COSMIC	4.103	Down-regulation
AGC_RSK_RSKp70_RPS6KB2_ST	O00418	EEF2K	Q9UBS0	RPS6KB2	S377	P371S	371	Missense	distal	-6	no	6.398	6.249	EPSD	TCGA;ICGC;COSMIC	4.103	Down-regulation
AGC_RSK_RSKp70_RPS6KB2_ST	P09651	HNRNPA1	Q9UBS0	RPS6KB2	S6	E5Q	5	Missense	proximal	-1	no	7.662	7.332	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	4.103	Down-regulation
AGC_RSK_RSKp70_RPS6KB2_ST	P09651	HNRNPA1	Q9UBS0	RPS6KB2	S6	P7R	7	Missense	proximal	1	no	7.662	7.516	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	4.103	Down-regulation
AGC_RSK_RSKp70_RPS6KB2_ST	P09651	HNRNPA1	Q9UBS0	RPS6KB2	S6	P10S	10	Missense	distal	4	no	7.662	7.896	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	4.103	Up-regulation
AGC_RSK_RSKp70_RPS6KB2_ST	P09651	HNRNPA1	Q9UBS0	RPS6KB2	S6	L13P	13	Missense	distal	7	no	7.662	7.659	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	4.103	Down-regulation
AGC_RSK_RSKp70_RPS6KB2_ST	P09651	HNRNPA1	Q9UBS0	RPS6KB2	S91	R97T	97	Missense	distal	6	no	6.596	6.468	EPSD	TCGA;ICGC;COSMIC	4.103	Down-regulation
AGC_RSK_RSKp70_RPS6KB2_ST	P09651	HNRNPA1	Q9UBS0	RPS6KB2	S95	R97T	97	Missense	proximal	2	no	6.790	6.872	EPSD	TCGA;ICGC;COSMIC	4.103	Up-regulation
AGC_RSK_RSKp70_RPS6KB2_ST	P09651	HNRNPA1	Q9UBS0	RPS6KB2	S182	E185D	185	Missense	distal	3	no	5.921	5.889	EPSD	TCGA;ICGC;COSMIC	4.103	Down-regulation
AGC_RSK_RSKp70_RPS6KB2_ST	P09651	HNRNPA1	Q9UBS0	RPS6KB2	S182	E185K	185	Missense	distal	3	no	5.921	5.836	EPSD	TCGA;ICGC;COSMIC	4.103	Down-regulation
AGC_RSK_RSKp70_RPS6KB2_ST	P09651	HNRNPA1	Q9UBS0	RPS6KB2	S182	R178K	178	Missense	distal	-4	no	5.921	5.864	EPSD	TCGA;ICGC;COSMIC	4.103	Down-regulation
AGC_RSK_RSKp70_RPS6KB2_ST	P09651	HNRNPA1	Q9UBS0	RPS6KB2	S182	A180D	180	Missense	proximal	-2	no	5.921	6.008	EPSD	TCGA;ICGC;COSMIC	4.103	Up-regulation
AGC_RSK_RSKp70_RPS6KB2_ST	P09651	HNRNPA1	Q9UBS0	RPS6KB2	S188	E185K	185	Missense	distal	-3	no	2.564	5.227	EPSD	TCGA;ICGC;COSMIC	4.103	Gain
AGC_RSK_RSKp70_RPS6KB2_ST	P09651	HNRNPA1	Q9UBS0	RPS6KB2	S197	R194T	194	Missense	distal	-3	no	6.020	1.379	EPSD	TCGA;ICGC;COSMIC	4.103	Loss
AGC_RSK_RSKp70_RPS6KB2_ST	P09651	HNRNPA1	Q9UBS0	RPS6KB2	S197	G200A	200	Missense	distal	3	no	6.020	5.999	EPSD	TCGA;ICGC;COSMIC	4.103	Down-regulation
AGC_RSK_RSKp70_RPS6KB2_ST	P09651	HNRNPA1	Q9UBS0	RPS6KB2	S197	G198C	198	Missense	proximal	1	no	6.020	5.744	EPSD	TCGA;ICGC;COSMIC	4.103	Down-regulation
AGC_RSK_RSKp70_RPS6KB2_ST	P09651	HNRNPA1	Q9UBS0	RPS6KB2	S199	R194T	194	Missense	distal	-5	no	7.042	6.835	EPSD	TCGA;ICGC;COSMIC	4.103	Down-regulation
AGC_RSK_RSKp70_RPS6KB2_ST	P09651	HNRNPA1	Q9UBS0	RPS6KB2	S199	G200A	200	Missense	proximal	1	no	7.042	6.856	EPSD	TCGA;ICGC;COSMIC	4.103	Down-regulation
AGC_RSK_RSKp70_RPS6KB2_ST	P09651	HNRNPA1	Q9UBS0	RPS6KB2	S199	G198C	198	Missense	proximal	-1	no	7.042	8.124	EPSD	TCGA;ICGC;COSMIC	4.103	Up-regulation
AGC_RSK_RSKp70_RPS6KB2_ST	P09651	HNRNPA1	Q9UBS0	RPS6KB2	S286	G283R	283	Missense	distal	-3	no	3.217	8.385	EPSD	TCGA;ICGC;COSMIC	4.103	Gain
AGC_RSK_RSKp70_RPS6KB2_ST	Q6R327	RICTOR	Q9UBS0	RPS6KB2	S21	R18L	18	Missense	distal	-3	no	6.466	0.451	EPSD	TCGA;ICGC;COSMIC	4.103	Loss
AGC_RSK_RSKp70_RPS6KB2_ST	Q6R327	RICTOR	Q9UBS0	RPS6KB2	S35	D36N	36	Missense	proximal	1	no	5.932	6.035	EPSD	TCGA;ICGC;COSMIC	4.103	Up-regulation
AGC_RSK_RSKp70_RPS6KB2_ST	Q6R327	RICTOR	Q9UBS0	RPS6KB2	S35	L42F	42	Missense	distal	7	no	5.932	5.927	EPSD	TCGA;ICGC;COSMIC	4.103	Down-regulation
AGC_RSK_RSKp70_RPS6KB2_ST	Q6R327	RICTOR	Q9UBS0	RPS6KB2	S35	E40K	40	Missense	distal	5	no	5.932	5.887	EPSD	TCGA;ICGC;COSMIC	4.103	Down-regulation
AGC_RSK_RSKp70_RPS6KB2_ST	Q6R327	RICTOR	Q9UBS0	RPS6KB2	S35	L30V	30	Missense	distal	-5	no	5.932	5.935	EPSD	TCGA;ICGC;COSMIC	4.103	Up-regulation
AGC_RSK_RSKp70_RPS6KB2_ST	Q6R327	RICTOR	Q9UBS0	RPS6KB2	S383	H379R	379	Missense	distal	-4	no	6.174	6.342	EPSD	TCGA;ICGC;COSMIC	4.103	Up-regulation
AGC_RSK_RSKp70_RPS6KB2_ST	Q6R327	RICTOR	Q9UBS0	RPS6KB2	S383	R380H	380	Missense	distal	-3	no	6.174	1.883	EPSD	TCGA;ICGC;COSMIC	4.103	Loss
AGC_RSK_RSKp70_RPS6KB2_ST	Q6R327	RICTOR	Q9UBS0	RPS6KB2	S810	R807I	807	Missense	distal	-3	no	7.073	1.658	EPSD	TCGA;COSMIC	4.103	Loss
AGC_RSK_RSKp70_RPS6KB2_ST	Q6R327	RICTOR	Q9UBS0	RPS6KB2	S1035	S1042L	1042	Missense	distal	7	no	6.417	6.415	EPSD	TCGA;ICGC;COSMIC	4.103	Down-regulation
AGC_RSK_RSKp70_RPS6KB2_ST	Q6R327	RICTOR	Q9UBS0	RPS6KB2	S1035	E1038G	1038	Missense	distal	3	no	6.417	6.436	EPSD	TCGA;ICGC;COSMIC	4.103	Up-regulation
AGC_RSK_RSKp70_RPS6KB2_ST	Q6R327	RICTOR	Q9UBS0	RPS6KB2	S1122	G1117E	1117	Missense	distal	-5	no	5.186	5.207	EPSD	TCGA;ICGC;COSMIC	4.103	Up-regulation
AGC_RSK_RSKp70_RPS6KB2_ST	Q6R327	RICTOR	Q9UBS0	RPS6KB2	S1122	L1120V	1120	Missense	proximal	-2	no	5.186	4.447	EPSD	TCGA;ICGC	4.103	Down-regulation
AGC_RSK_RSKp70_RPS6KB2_ST	Q6R327	RICTOR	Q9UBS0	RPS6KB2	T1133	T1135M	1135	Missense	proximal	2	no	4.380	4.464	EPSD	TCGA;ICGC;COSMIC	4.103	Up-regulation
AGC_RSK_RSKp70_RPS6KB2_ST	Q6R327	RICTOR	Q9UBS0	RPS6KB2	T1133	R1130Q	1130	Missense	distal	-3	no	4.380	-0.390	EPSD	TCGA;ICGC;COSMIC;GDSC;CCLE	4.103	Loss
AGC_RSK_RSKp70_RPS6KB2_ST	Q6R327	RICTOR	Q9UBS0	RPS6KB2	T1135	T1135M	1135	Missense	central	0	yes	9.512	0.000	PhosphoSitePlus	TCGA;ICGC;COSMIC	4.103	Loss
AGC_RSK_RSKp70_RPS6KB2_ST	Q6R327	RICTOR	Q9UBS0	RPS6KB2	T1135	R1130Q	1130	Missense	distal	-5	no	9.512	9.251	PhosphoSitePlus	TCGA;ICGC;COSMIC;GDSC;CCLE	4.103	Down-regulation
AGC_RSK_RSKp70_RPS6KB2_ST	Q6R327	RICTOR	Q9UBS0	RPS6KB2	T1198	E1196Q	1196	Missense	proximal	-2	no	4.999	5.130	EPSD	TCGA;ICGC;COSMIC	4.103	Up-regulation
AGC_RSK_RSKp70_RPS6KB2_ST	Q6R327	RICTOR	Q9UBS0	RPS6KB2	T1198	R1200Q	1200	Missense	proximal	2	no	4.999	5.159	EPSD	TCGA;ICGC;COSMIC	4.103	Up-regulation
AGC_RSK_RSKp70_RPS6KB2_ST	Q6R327	RICTOR	Q9UBS0	RPS6KB2	S1219	T1222I	1222	Missense	distal	3	no	8.046	8.121	EPSD	TCGA;ICGC;COSMIC	4.103	Up-regulation
AGC_RSK_RSKp70_RPS6KB2_ST	Q6R327	RICTOR	Q9UBS0	RPS6KB2	S1219	R1216H	1216	Missense	distal	-3	no	8.046	3.755	EPSD	TCGA;ICGC;COSMIC;CCLE	4.103	Loss
AGC_RSK_RSKp70_RPS6KB2_ST	Q6R327	RICTOR	Q9UBS0	RPS6KB2	S1302	R1299G	1299	Missense	distal	-3	no	5.813	0.646	EPSD	TCGA;ICGC;COSMIC	4.103	Loss
AGC_RSK_RSKp70_RPS6KB2_ST	Q6R327	RICTOR	Q9UBS0	RPS6KB2	S1302	A1305S	1305	Missense	distal	3	no	5.813	5.695	EPSD	TCGA;ICGC;COSMIC	4.103	Down-regulation
AGC_RSK_RSKp70_RPS6KB2_ST	Q6R327	RICTOR	Q9UBS0	RPS6KB2	S1307	A1305S	1305	Missense	proximal	-2	no	4.003	4.753	EPSD	TCGA;ICGC;COSMIC	4.103	Gain
AGC_RSK_RSKp70_RPS6KB2_ST	Q6R327	RICTOR	Q9UBS0	RPS6KB2	S1385	K1382Q	1382	Missense	distal	-3	no	4.713	2.650	EPSD	TCGA;ICGC	4.103	Loss
AGC_RSK_RSKp70_RPS6KB2_ST	Q6R327	RICTOR	Q9UBS0	RPS6KB2	S1385	M1381V	1381	Missense	distal	-4	no	4.713	4.709	EPSD	TCGA;ICGC;COSMIC	4.103	Down-regulation
AGC_RSK_RSKp70_RPS6KB2_ST	Q6R327	RICTOR	Q9UBS0	RPS6KB2	S1385	S1378N	1378	Missense	distal	-7	no	4.713	4.915	EPSD	TCGA;ICGC;COSMIC	4.103	Up-regulation
AGC_RSK_RSKp70_RPS6KB2_ST	Q6R327	RICTOR	Q9UBS0	RPS6KB2	S1408	S1407F	1407	Missense	proximal	-1	no	7.257	6.090	EPSD	TCGA;ICGC;COSMIC	4.103	Down-regulation
AGC_RSK_RSKp70_RPS6KB2_ST	Q6R327	RICTOR	Q9UBS0	RPS6KB2	S1408	R1405Q	1405	Missense	distal	-3	no	7.257	2.488	EPSD	TCGA;ICGC;COSMIC	4.103	Loss
TK_Src_SrcA_FGR_Y	P09917	ALOX5	P09769	FGR	Y75	D79Y	79	Missense	distal	4	no	7.615	6.959	EPSD	TCGA	5.114	Down-regulation
TK_Src_SrcA_FGR_Y	P09917	ALOX5	P09769	FGR	Y75	E71K	71	Missense	distal	-4	no	7.615	7.640	EPSD	TCGA;ICGC;COSMIC	5.114	Up-regulation
TK_Src_SrcA_FGR_Y	Q05397	PTK2	P09769	FGR	Y397	E403K	403	Missense	distal	6	no	10.061	10.143	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	5.114	Up-regulation
TK_Src_SrcA_FGR_Y	Q05397	PTK2	P09769	FGR	Y397	D395Y	395	Missense	proximal	-2	no	10.061	9.906	EPSD;PhosphoSitePlus	TCGA;ICGC	5.114	Down-regulation
TK_Src_SrcA_FGR_Y	Q05397	PTK2	P09769	FGR	Y397	E404G	404	Missense	distal	7	no	10.061	7.950	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	5.114	Down-regulation
TK_Src_SrcA_FGR_Y	Q05397	PTK2	P09769	FGR	Y441	A448T	448	Missense	distal	7	no	5.191	5.035	EPSD	TCGA;ICGC;COSMIC	5.114	Loss
TK_Src_SrcA_FGR_Y	Q05397	PTK2	P09769	FGR	Y441	A448D	448	Missense	distal	7	no	5.191	5.577	EPSD	TCGA;ICGC;COSMIC	5.114	Up-regulation
TK_Src_SrcA_FGR_Y	Q9UHD2	TBK1	P09769	FGR	Y340	E337K	337	Missense	distal	-3	no	5.205	4.356	EPSD	TCGA;ICGC;COSMIC	5.114	Loss
TK_Src_SrcA_FGR_Y	Q9UHD2	TBK1	P09769	FGR	Y340	F335V	335	Missense	distal	-5	no	5.205	5.166	EPSD	TCGA;ICGC;COSMIC	5.114	Down-regulation
TK_Src_SrcA_FGR_Y	Q9UHD2	TBK1	P09769	FGR	Y354	E355K	355	Missense	proximal	1	no	9.835	9.267	PhosphoSitePlus;EPSD	TCGA;ICGC;COSMIC	5.114	Down-regulation
TK_Src_SrcA_FGR_Y	Q9UHD2	TBK1	P09769	FGR	Y577	E580K	580	Missense	distal	3	no	7.400	7.373	EPSD	TCGA;ICGC;COSMIC	5.114	Down-regulation
TK_Src_SrcA_FGR_Y	Q9UHD2	TBK1	P09769	FGR	Y577	R574G	574	Missense	distal	-3	no	7.400	7.165	EPSD	TCGA;ICGC;COSMIC	5.114	Down-regulation
TK_Src_SRM_Y	Q13882	PTK6	Q13882	PTK6	Y13	G10D	10	Missense	distal	-3	no	1.093	1.239	EPSD	TCGA;ICGC	1.179	Gain
TK_Src_SRM_Y	Q13882	PTK6	Q13882	PTK6	Y61	G54D	54	Missense	distal	-7	no	1.564	1.615	EPSD	TCGA;ICGC;COSMIC	1.179	Up-regulation
TK_Src_SRM_Y	Q13882	PTK6	Q13882	PTK6	Y61	G60V	60	Missense	proximal	-1	no	1.564	1.575	EPSD	TCGA;ICGC;COSMIC	1.179	Up-regulation
TK_Src_SRM_Y	Q13882	PTK6	Q13882	PTK6	Y66	G60V	60	Missense	distal	-6	no	2.496	2.485	EPSD	TCGA;ICGC;COSMIC	1.179	Down-regulation
TK_Src_SRM_Y	Q13882	PTK6	Q13882	PTK6	Y447	E448K	448	Missense	proximal	1	no	3.022	2.989	PhosphoSitePlus;EPSD	TCGA;ICGC	1.179	Down-regulation
TK_Src_SRM_PTK6_Y	Q13882	PTK6	Q13882	PTK6	Y13	H8Q	8	Missense	distal	-5	no	21.269	19.827	EPSD	TCGA;ICGC;COSMIC	13.984	Down-regulation
TK_Src_SRM_PTK6_Y	Q13882	PTK6	Q13882	PTK6	Y13	G10D	10	Missense	distal	-3	no	21.269	23.101	EPSD	TCGA;ICGC	13.984	Up-regulation
TK_Src_SRM_PTK6_Y	Q13882	PTK6	Q13882	PTK6	Y61	G54D	54	Missense	distal	-7	no	29.459	30.063	EPSD	TCGA;ICGC;COSMIC	13.984	Up-regulation
TK_Src_SRM_PTK6_Y	Q13882	PTK6	Q13882	PTK6	Y61	G60V	60	Missense	proximal	-1	no	29.459	29.444	EPSD	TCGA;ICGC;COSMIC	13.984	Down-regulation
TK_Src_SRM_PTK6_Y	Q13882	PTK6	Q13882	PTK6	Y66	G60V	60	Missense	distal	-6	no	35.898	36.056	EPSD	TCGA;ICGC;COSMIC	13.984	Up-regulation
TK_Src_SRM_PTK6_Y	Q13882	PTK6	Q13882	PTK6	Y114	Y114H	114	Missense	central	0	yes	19.659	0.000	EPSD	TCGA;ICGC;COSMIC	13.984	Loss
TK_Src_SRM_PTK6_Y	Q13882	PTK6	Q13882	PTK6	Y114	P110Q	110	Missense	distal	-4	no	19.659	20.155	EPSD	TCGA;ICGC	13.984	Up-regulation
TK_Src_SRM_PTK6_Y	Q13882	PTK6	Q13882	PTK6	Y351	P356L	356	Missense	distal	5	no	21.722	23.815	EPSD	TCGA;ICGC;COSMIC	13.984	Up-regulation
TK_Src_SRM_PTK6_Y	Q13882	PTK6	Q13882	PTK6	Y351	P356S	356	Missense	distal	5	no	21.722	20.384	EPSD	TCGA;ICGC;COSMIC	13.984	Down-regulation
TK_Src_SRM_PTK6_Y	Q13882	PTK6	Q13882	PTK6	Y351	A355T	355	Missense	distal	4	no	21.722	21.775	EPSD	TCGA;ICGC;COSMIC	13.984	Up-regulation
TK_Src_SRM_PTK6_Y	Q13882	PTK6	Q13882	PTK6	Y447	E448K	448	Missense	proximal	1	no	39.672	39.537	PhosphoSitePlus;EPSD	TCGA;ICGC	13.984	Down-regulation
TK_Src_SRM_Y	P35222	CTNNB1	Q13882	PTK6	Y30	S33P	33	Missense	distal	3	no	0.870	1.725	EPSD	TCGA;COSMIC	1.179	Gain
TK_Src_SRM_Y	P35222	CTNNB1	Q13882	PTK6	Y64	S60F	60	Missense	distal	-4	no	2.081	2.186	EPSD;PhosphoSitePlus	TCGA;COSMIC	1.179	Up-regulation
TK_Src_SRM_Y	P35222	CTNNB1	Q13882	PTK6	Y331	E334A	334	Missense	distal	3	no	2.092	1.760	EPSD;PhosphoSitePlus	TCGA;COSMIC	1.179	Down-regulation
TK_Src_SRM_Y	P35222	CTNNB1	Q13882	PTK6	Y331	K335T	335	Missense	distal	4	no	2.092	2.091	EPSD;PhosphoSitePlus	TCGA;COSMIC	1.179	Down-regulation
TK_Src_SRM_Y	P35222	CTNNB1	Q13882	PTK6	Y331	K335I	335	Missense	distal	4	no	2.092	2.126	EPSD;PhosphoSitePlus	TCGA;COSMIC	1.179	Up-regulation
TK_Src_SRM_Y	P35222	CTNNB1	Q13882	PTK6	Y331	Y333F	333	Missense	proximal	2	no	2.092	2.129	EPSD;PhosphoSitePlus	TCGA;COSMIC	1.179	Up-regulation
TK_Src_SRM_Y	P35222	CTNNB1	Q13882	PTK6	Y331	M328I	328	Missense	distal	-3	no	2.092	2.015	EPSD;PhosphoSitePlus	TCGA;COSMIC	1.179	Down-regulation
TK_Src_SRM_Y	P35222	CTNNB1	Q13882	PTK6	Y331	E334K	334	Missense	distal	3	no	2.092	1.399	EPSD;PhosphoSitePlus	TCGA;COSMIC	1.179	Down-regulation
TK_Src_SRM_Y	P35222	CTNNB1	Q13882	PTK6	Y331	L336P	336	Missense	distal	5	no	2.092	1.837	EPSD;PhosphoSitePlus	TCGA;COSMIC	1.179	Down-regulation
TK_Src_SRM_Y	P35222	CTNNB1	Q13882	PTK6	Y333	E334A	334	Missense	proximal	1	no	1.300	1.272	EPSD;PhosphoSitePlus	TCGA;COSMIC	1.179	Down-regulation
TK_Src_SRM_Y	P35222	CTNNB1	Q13882	PTK6	Y333	K335T	335	Missense	proximal	2	no	1.300	1.323	EPSD;PhosphoSitePlus	TCGA;COSMIC	1.179	Up-regulation
TK_Src_SRM_Y	P35222	CTNNB1	Q13882	PTK6	Y333	K335I	335	Missense	proximal	2	no	1.300	1.403	EPSD;PhosphoSitePlus	TCGA;COSMIC	1.179	Up-regulation
TK_Src_SRM_Y	P35222	CTNNB1	Q13882	PTK6	Y333	Y333F	333	Missense	central	0	yes	1.300	0.000	EPSD;PhosphoSitePlus	TCGA;COSMIC	1.179	Loss
TK_Src_SRM_Y	P35222	CTNNB1	Q13882	PTK6	Y333	M328I	328	Missense	distal	-5	no	1.300	1.342	EPSD;PhosphoSitePlus	TCGA;COSMIC	1.179	Up-regulation
TK_Src_SRM_Y	P35222	CTNNB1	Q13882	PTK6	Y333	T339N	339	Missense	distal	6	no	1.300	1.317	EPSD;PhosphoSitePlus	TCGA;COSMIC	1.179	Up-regulation
TK_Src_SRM_Y	P35222	CTNNB1	Q13882	PTK6	Y333	E334K	334	Missense	proximal	1	no	1.300	1.266	EPSD;PhosphoSitePlus	TCGA;COSMIC	1.179	Down-regulation
TK_Src_SRM_Y	P35222	CTNNB1	Q13882	PTK6	Y333	L336P	336	Missense	distal	3	no	1.300	2.297	EPSD;PhosphoSitePlus	TCGA;COSMIC	1.179	Up-regulation
TK_Src_SRM_Y	P35222	CTNNB1	Q13882	PTK6	Y724	R717H	717	Missense	distal	-7	no	1.285	1.327	EPSD	TCGA;COSMIC	1.179	Up-regulation
TK_Src_SRM_PTK6_Y	P35222	CTNNB1	Q13882	PTK6	Y30	S33P	33	Missense	distal	3	no	8.909	21.568	EPSD	TCGA;COSMIC;CCLE	13.984	Gain
TK_Src_SRM_PTK6_Y	P35222	CTNNB1	Q13882	PTK6	Y64	S60F	60	Missense	distal	-4	no	27.456	29.161	EPSD;PhosphoSitePlus	TCGA;COSMIC	13.984	Up-regulation
TK_Src_SRM_PTK6_Y	P35222	CTNNB1	Q13882	PTK6	Y142	V136A	136	Missense	distal	-6	no	16.974	16.063	PhosphoSitePlus;EPSD	TCGA;COSMIC	13.984	Down-regulation
TK_Src_SRM_PTK6_Y	P35222	CTNNB1	Q13882	PTK6	Y142	I140N	140	Missense	proximal	-2	no	16.974	18.544	PhosphoSitePlus;EPSD	TCGA	13.984	Up-regulation
TK_Src_SRM_PTK6_Y	P35222	CTNNB1	Q13882	PTK6	Y142	D144E	144	Missense	proximal	2	no	16.974	16.564	PhosphoSitePlus;EPSD	TCGA;COSMIC	13.984	Down-regulation
TK_Src_SRM_PTK6_Y	P35222	CTNNB1	Q13882	PTK6	Y331	E334A	334	Missense	distal	3	no	29.435	25.008	EPSD;PhosphoSitePlus	TCGA;COSMIC	13.984	Down-regulation
TK_Src_SRM_PTK6_Y	P35222	CTNNB1	Q13882	PTK6	Y331	K335T	335	Missense	distal	4	no	29.435	29.283	EPSD;PhosphoSitePlus	TCGA;COSMIC	13.984	Down-regulation
TK_Src_SRM_PTK6_Y	P35222	CTNNB1	Q13882	PTK6	Y331	K335I	335	Missense	distal	4	no	29.435	29.830	EPSD;PhosphoSitePlus	TCGA;COSMIC	13.984	Up-regulation
TK_Src_SRM_PTK6_Y	P35222	CTNNB1	Q13882	PTK6	Y331	Y333F	333	Missense	proximal	2	no	29.435	30.481	EPSD;PhosphoSitePlus	TCGA;COSMIC	13.984	Up-regulation
TK_Src_SRM_PTK6_Y	P35222	CTNNB1	Q13882	PTK6	Y331	M328I	328	Missense	distal	-3	no	29.435	27.139	EPSD;PhosphoSitePlus	TCGA;COSMIC	13.984	Down-regulation
TK_Src_SRM_PTK6_Y	P35222	CTNNB1	Q13882	PTK6	Y331	E334K	334	Missense	distal	3	no	29.435	19.693	EPSD;PhosphoSitePlus	TCGA;COSMIC;GDSC;CCLE	13.984	Down-regulation
TK_Src_SRM_PTK6_Y	P35222	CTNNB1	Q13882	PTK6	Y331	L336P	336	Missense	distal	5	no	29.435	27.342	EPSD;PhosphoSitePlus	TCGA;COSMIC	13.984	Down-regulation
TK_Src_SRM_PTK6_Y	P35222	CTNNB1	Q13882	PTK6	Y333	E334A	334	Missense	proximal	1	no	26.739	26.222	EPSD;PhosphoSitePlus	TCGA;COSMIC	13.984	Down-regulation
TK_Src_SRM_PTK6_Y	P35222	CTNNB1	Q13882	PTK6	Y333	K335T	335	Missense	proximal	2	no	26.739	26.899	EPSD;PhosphoSitePlus	TCGA;COSMIC	13.984	Up-regulation
TK_Src_SRM_PTK6_Y	P35222	CTNNB1	Q13882	PTK6	Y333	K335I	335	Missense	proximal	2	no	26.739	27.916	EPSD;PhosphoSitePlus	TCGA;COSMIC	13.984	Up-regulation
TK_Src_SRM_PTK6_Y	P35222	CTNNB1	Q13882	PTK6	Y333	Y333F	333	Missense	central	0	yes	26.739	0.000	EPSD;PhosphoSitePlus	TCGA;COSMIC	13.984	Loss
TK_Src_SRM_PTK6_Y	P35222	CTNNB1	Q13882	PTK6	Y333	M328I	328	Missense	distal	-5	no	26.739	28.043	EPSD;PhosphoSitePlus	TCGA;COSMIC	13.984	Up-regulation
TK_Src_SRM_PTK6_Y	P35222	CTNNB1	Q13882	PTK6	Y333	T339N	339	Missense	distal	6	no	26.739	26.082	EPSD;PhosphoSitePlus	TCGA;COSMIC	13.984	Down-regulation
TK_Src_SRM_PTK6_Y	P35222	CTNNB1	Q13882	PTK6	Y333	E334K	334	Missense	proximal	1	no	26.739	26.604	EPSD;PhosphoSitePlus	TCGA;COSMIC;GDSC;CCLE	13.984	Down-regulation
TK_Src_SRM_PTK6_Y	P35222	CTNNB1	Q13882	PTK6	Y333	L336P	336	Missense	distal	3	no	26.739	38.866	EPSD;PhosphoSitePlus	TCGA;COSMIC	13.984	Up-regulation
TK_Src_SRM_PTK6_Y	P35222	CTNNB1	Q13882	PTK6	Y724	R717H	717	Missense	distal	-7	no	14.615	15.366	EPSD	TCGA;COSMIC	13.984	Up-regulation
TK_Src_SRM_Y	Q9UGK3	STAP2	Q13882	PTK6	Y310	Q306H	306	Missense	distal	-4	no	1.684	1.697	EPSD	TCGA;ICGC	1.179	Up-regulation
TK_Src_SRM_Y	Q9UGK3	STAP2	Q13882	PTK6	Y310	G317D	317	Missense	distal	7	no	1.684	1.625	EPSD	TCGA;ICGC;COSMIC	1.179	Down-regulation
TK_Src_SRM_PTK6_Y	Q9UGK3	STAP2	Q13882	PTK6	Y310	Q306H	306	Missense	distal	-4	no	16.841	17.619	EPSD	TCGA;ICGC	13.984	Up-regulation
TK_Src_SRM_PTK6_Y	Q9UGK3	STAP2	Q13882	PTK6	Y310	G317D	317	Missense	distal	7	no	16.841	16.224	EPSD	TCGA;ICGC;COSMIC;GDSC;CCLE	13.984	Down-regulation
TK_Src_SRM_PTK6_Y	Q96P48	ARAP1	Q13882	PTK6	Y231	P235S	235	Missense	distal	4	no	16.940	17.228	PhosphoSitePlus	TCGA;ICGC;COSMIC	13.984	Up-regulation
TK_Src_SRM_PTK6_Y	Q96P48	ARAP1	Q13882	PTK6	Y737	P742L	742	Missense	distal	5	no	16.376	18.469	EPSD	TCGA;COSMIC	13.984	Up-regulation
TK_Src_SRM_PTK6_Y	Q96P48	ARAP1	Q13882	PTK6	Y737	T743A	743	Missense	distal	6	no	16.376	15.801	EPSD	TCGA;ICGC;COSMIC	13.984	Down-regulation
TK_Src_SRM_Y	P31749	AKT1	Q13882	PTK6	Y315	E322K	322	Missense	distal	7	no	2.431	2.478	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	1.179	Up-regulation
TK_Src_SRM_Y	P31749	AKT1	Q13882	PTK6	Y315	G311D	311	Missense	distal	-4	no	2.431	2.373	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	1.179	Down-regulation
TK_Src_SRM_Y	P31749	AKT1	Q13882	PTK6	Y326	D323N	323	Missense	distal	-3	no	2.808	2.787	PhosphoSitePlus;EPSD	TCGA;ICGC;COSMIC	1.179	Down-regulation
TK_Src_SRM_Y	P31749	AKT1	Q13882	PTK6	Y326	D323Y	323	Missense	distal	-3	no	2.808	2.644	PhosphoSitePlus;EPSD	TCGA;ICGC;COSMIC	1.179	Down-regulation
TK_Src_SRM_Y	P31749	AKT1	Q13882	PTK6	Y326	E322K	322	Missense	distal	-4	no	2.808	2.840	PhosphoSitePlus;EPSD	TCGA;ICGC;COSMIC	1.179	Up-regulation
TK_Src_SRM_Y	P31749	AKT1	Q13882	PTK6	Y437	S431L	431	Missense	distal	-6	no	1.230	1.306	EPSD	TCGA;ICGC;COSMIC	1.179	Up-regulation
TK_Src_SRM_PTK6_Y	P31749	AKT1	Q13882	PTK6	Y315	E322K	322	Missense	distal	7	no	34.424	34.702	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	13.984	Up-regulation
TK_Src_SRM_PTK6_Y	P31749	AKT1	Q13882	PTK6	Y315	G311D	311	Missense	distal	-4	no	34.424	33.721	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC;GDSC;CCLE	13.984	Down-regulation
TK_Src_SRM_PTK6_Y	P31749	AKT1	Q13882	PTK6	Y326	D323N	323	Missense	distal	-3	no	29.725	30.370	PhosphoSitePlus;EPSD	TCGA;ICGC;COSMIC	13.984	Up-regulation
TK_Src_SRM_PTK6_Y	P31749	AKT1	Q13882	PTK6	Y326	D323Y	323	Missense	distal	-3	no	29.725	27.458	PhosphoSitePlus;EPSD	TCGA;ICGC;COSMIC	13.984	Down-regulation
TK_Src_SRM_PTK6_Y	P31749	AKT1	Q13882	PTK6	Y326	E322K	322	Missense	distal	-4	no	29.725	29.844	PhosphoSitePlus;EPSD	TCGA;ICGC;COSMIC	13.984	Up-regulation
TK_Src_SRM_PTK6_Y	P31749	AKT1	Q13882	PTK6	Y437	S431L	431	Missense	distal	-6	no	13.371	14.382	EPSD	TCGA;ICGC;COSMIC	13.984	Gain
TK_Src_SRM_Y	P51692	STAT5B	Q13882	PTK6	Y699	A695T	695	Missense	distal	-4	no	1.817	1.837	PhosphoSitePlus	TCGA	1.179	Up-regulation
TK_Src_SRM_Y	P51692	STAT5B	Q13882	PTK6	Y699	I704T	704	Missense	distal	5	no	1.817	1.593	PhosphoSitePlus	TCGA;ICGC;COSMIC	1.179	Down-regulation
TK_Src_SRM_Y	P51692	STAT5B	Q13882	PTK6	Y699	V700L	700	Missense	proximal	1	no	1.817	1.827	PhosphoSitePlus	TCGA;ICGC;COSMIC	1.179	Up-regulation
TK_Src_SRM_Y	P51692	STAT5B	Q13882	PTK6	Y699	A695V	695	Missense	distal	-4	no	1.817	1.871	PhosphoSitePlus	TCGA;ICGC;COSMIC	1.179	Up-regulation
TK_Src_SRM_PTK6_Y	P51692	STAT5B	Q13882	PTK6	Y683	S680F	680	Missense	distal	-3	no	18.711	13.508	EPSD	TCGA;ICGC;COSMIC	13.984	Loss
TK_Src_SRM_PTK6_Y	P51692	STAT5B	Q13882	PTK6	Y699	A695T	695	Missense	distal	-4	no	28.331	27.978	PhosphoSitePlus	TCGA	13.984	Down-regulation
TK_Src_SRM_PTK6_Y	P51692	STAT5B	Q13882	PTK6	Y699	I704T	704	Missense	distal	5	no	28.331	24.459	PhosphoSitePlus	TCGA;ICGC;COSMIC	13.984	Down-regulation
TK_Src_SRM_PTK6_Y	P51692	STAT5B	Q13882	PTK6	Y699	V700L	700	Missense	proximal	1	no	28.331	28.464	PhosphoSitePlus	TCGA;ICGC;COSMIC	13.984	Up-regulation
TK_Src_SRM_PTK6_Y	P51692	STAT5B	Q13882	PTK6	Y699	A695V	695	Missense	distal	-4	no	28.331	28.819	PhosphoSitePlus	TCGA;ICGC;COSMIC	13.984	Up-regulation
TK_Src_SRM_Y	P49023	PXN	Q13882	PTK6	Y31	E27G	27	Missense	distal	-4	no	2.040	2.147	EPSD;PhosphoSitePlus	TCGA	1.179	Up-regulation
TK_Src_SRM_Y	P49023	PXN	Q13882	PTK6	Y181	S188N	188	Missense	distal	7	no	1.228	1.282	EPSD	TCGA	1.179	Up-regulation
TK_Src_SRM_PTK6_Y	P49023	PXN	Q13882	PTK6	Y31	E27G	27	Missense	distal	-4	no	28.873	30.123	EPSD;PhosphoSitePlus	TCGA	13.984	Up-regulation
TK_Src_SRM_PTK6_Y	P49023	PXN	Q13882	PTK6	Y118	Q124H	124	Missense	distal	6	no	19.182	20.577	PhosphoSitePlus;EPSD	TCGA;COSMIC	13.984	Up-regulation
TK_Src_SRM_PTK6_Y	P49023	PXN	Q13882	PTK6	Y181	S188N	188	Missense	distal	7	no	15.662	15.670	EPSD	TCGA	13.984	Up-regulation
TK_Src_SRM_Y	Q13017	ARHGAP5	Q13882	PTK6	Y587	R583H	583	Missense	distal	-4	no	1.213	1.162	EPSD	TCGA;ICGC;COSMIC	1.179	Loss
TK_Src_SRM_Y	Q13017	ARHGAP5	Q13882	PTK6	Y587	D594Y	594	Missense	distal	7	no	1.213	1.266	EPSD	TCGA;ICGC;COSMIC	1.179	Up-regulation
TK_Src_SRM_Y	Q13017	ARHGAP5	Q13882	PTK6	Y1109	D1106H	1106	Missense	distal	-3	no	2.493	2.413	PhosphoSitePlus	TCGA;ICGC;COSMIC	1.179	Down-regulation
TK_Src_SRM_PTK6_Y	Q13017	ARHGAP5	Q13882	PTK6	Y587	D594Y	594	Missense	distal	7	no	13.144	14.062	EPSD	TCGA;ICGC;COSMIC	13.984	Gain
TK_Src_SRM_PTK6_Y	Q13017	ARHGAP5	Q13882	PTK6	Y1109	D1106H	1106	Missense	distal	-3	no	33.538	31.689	PhosphoSitePlus	TCGA;ICGC;COSMIC	13.984	Down-regulation
Other_ULK_ULK_ULK1_ST	Q16543	CDC37	O75385	ULK1	S127	S120G	120	Missense	distal	-7	no	30.139	27.412	EPSD	TCGA;ICGC;COSMIC	29.179	Loss
Other_ULK_ULK_ULK1_ST	Q16543	CDC37	O75385	ULK1	S127	D122Y	122	Missense	distal	-5	no	30.139	27.322	EPSD	TCGA;ICGC;COSMIC	29.179	Loss
Other_ULK_ULK_ULK1_ST	Q16543	CDC37	O75385	ULK1	S140	E137K	137	Missense	distal	-3	no	34.433	34.466	EPSD	TCGA;ICGC;COSMIC	29.179	Up-regulation
Other_ULK_ULK_ULK1_ST	Q16543	CDC37	O75385	ULK1	S339	V343I	343	Missense	distal	4	no	35.355	35.904	PhosphoSitePlus	TCGA;ICGC;COSMIC	29.179	Up-regulation
Other_ULK_ULK_ULK1_ST	Q16543	CDC37	O75385	ULK1	S339	R335H	335	Missense	distal	-4	no	35.355	36.481	PhosphoSitePlus	TCGA;ICGC;COSMIC	29.179	Up-regulation
Other_ULK_ULK_ULK1_ST	Q16543	CDC37	O75385	ULK1	S339	R335C	335	Missense	distal	-4	no	35.355	30.970	PhosphoSitePlus	TCGA;ICGC;COSMIC	29.179	Down-regulation
Other_ULK_ULK_ULK1_ST	Q16543	CDC37	O75385	ULK1	S339	L341F	341	Missense	proximal	2	no	35.355	34.490	PhosphoSitePlus	TCGA;ICGC;COSMIC	29.179	Down-regulation
Other_ULK_ULK_ULK1_ST	Q16543	CDC37	O75385	ULK1	S339	P344S	344	Missense	distal	5	no	35.355	33.776	PhosphoSitePlus	TCGA;ICGC;COSMIC	29.179	Down-regulation
Other_ULK_ULK_ULK1_ST	Q16543	CDC37	O75385	ULK1	S339	D338G	338	Missense	proximal	-1	no	35.355	36.137	PhosphoSitePlus	TCGA;ICGC;COSMIC	29.179	Up-regulation
Other_ULK_ULK_ULK1_ST	Q8N122	RPTOR	O75385	ULK1	S8	L10F	10	Missense	proximal	2	no	47.595	46.729	EPSD	TCGA;ICGC;COSMIC	29.179	Down-regulation
Other_ULK_ULK_ULK1_ST	Q8N122	RPTOR	O75385	ULK1	S8	L11M	11	Missense	distal	3	no	47.595	44.310	EPSD	TCGA;ICGC;COSMIC	29.179	Down-regulation
Other_ULK_ULK_ULK1_ST	Q8N122	RPTOR	O75385	ULK1	S48	S44C	44	Missense	distal	-4	no	32.222	28.578	EPSD	TCGA;ICGC;COSMIC	29.179	Loss
Other_ULK_ULK_ULK1_ST	Q8N122	RPTOR	O75385	ULK1	S48	K52N	52	Missense	distal	4	no	32.222	32.693	EPSD	TCGA;ICGC	29.179	Up-regulation
Other_ULK_ULK_ULK1_ST	Q8N122	RPTOR	O75385	ULK1	S738	N741S	741	Missense	distal	3	no	43.563	40.847	EPSD	TCGA	29.179	Down-regulation
Other_ULK_ULK_ULK1_ST	Q8N122	RPTOR	O75385	ULK1	S855	T857M	857	Missense	proximal	2	no	37.170	37.342	PhosphoSitePlus;EPSD	TCGA;COSMIC	29.179	Up-regulation
Other_ULK_ULK_ULK1_ST	Q8N122	RPTOR	O75385	ULK1	S859	T857M	857	Missense	proximal	-2	no	49.120	46.383	EPSD;PhosphoSitePlus	TCGA;COSMIC	29.179	Down-regulation
Other_ULK_ULK_ULK1_ST	Q8N122	RPTOR	O75385	ULK1	T1121	D1117E	1117	Missense	distal	-4	no	38.432	35.640	EPSD	TCGA;COSMIC	29.179	Down-regulation
Other_ULK_ULK_ULK1_ST	Q7Z3C6	ATG9A	O75385	ULK1	S14	P19S	19	Missense	distal	5	no	40.041	38.462	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	29.179	Down-regulation
Other_ULK_ULK_ULK1_ST	Q7Z3C6	ATG9A	O75385	ULK1	S14	R10H	10	Missense	distal	-4	no	40.041	41.167	EPSD;PhosphoSitePlus	TCGA;ICGC	29.179	Up-regulation
Other_ULK_ULK_ULK1_ST	Q7Z3C6	ATG9A	O75385	ULK1	S642	A649V	649	Missense	distal	7	no	29.488	29.725	EPSD	TCGA;COSMIC	29.179	Up-regulation
Other_ULK_ULK_ULK1_ST	Q7Z3C6	ATG9A	O75385	ULK1	S642	R645M	645	Missense	distal	3	no	29.488	29.382	EPSD	TCGA;COSMIC	29.179	Down-regulation
Other_ULK_ULK_ULK1_ST	Q7Z3C6	ATG9A	O75385	ULK1	S642	D638Y	638	Missense	distal	-4	no	29.488	21.747	EPSD	TCGA;COSMIC	29.179	Loss
Other_ULK_ULK_ULK1_ST	Q7Z3C6	ATG9A	O75385	ULK1	S642	Q640H	640	Missense	proximal	-2	no	29.488	32.390	EPSD	TCGA;COSMIC	29.179	Up-regulation
Other_ULK_ULK_ULK1_ST	Q7Z3C6	ATG9A	O75385	ULK1	S675	A682G	682	Missense	distal	7	no	43.821	43.397	EPSD	TCGA;COSMIC	29.179	Down-regulation
Other_ULK_ULK_ULK1_ST	Q7Z3C6	ATG9A	O75385	ULK1	S761	P767L	767	Missense	distal	6	no	39.220	39.095	PhosphoSitePlus;EPSD	TCGA;COSMIC	29.179	Down-regulation
Other_ULK_ULK_ULK1_ST	Q7Z3C6	ATG9A	O75385	ULK1	S761	S755Y	755	Missense	distal	-6	no	39.220	33.974	PhosphoSitePlus;EPSD	TCGA	29.179	Down-regulation
Other_ULK_ULK_ULK1_ST	Q7Z3C6	ATG9A	O75385	ULK1	S761	R758H	758	Missense	distal	-3	no	39.220	39.571	PhosphoSitePlus;EPSD	TCGA;COSMIC	29.179	Up-regulation
Other_ULK_ULK_ULK1_ST	Q7Z3C6	ATG9A	O75385	ULK1	S817	V823M	823	Missense	distal	6	no	35.891	36.544	EPSD	TCGA;COSMIC	29.179	Up-regulation
Other_ULK_ULK_ULK1_ST	P09467	FBP1	O75385	ULK1	T256	V258F	258	Missense	proximal	2	no	30.963	30.929	EPSD	TCGA;ICGC;COSMIC	29.179	Down-regulation
Other_ULK_ULK_ULK1_ST	P09467	FBP1	O75385	ULK1	T256	R255H	255	Missense	proximal	-1	no	30.963	31.186	EPSD	TCGA;ICGC;COSMIC	29.179	Up-regulation
Other_ULK_ULK_ULK1_ST	P09467	FBP1	O75385	ULK1	T298	V303L	303	Missense	distal	5	no	32.432	31.989	EPSD	TCGA;ICGC;COSMIC	29.179	Down-regulation
Other_ULK_ULK_ULK1_ST	P09467	FBP1	O75385	ULK1	T298	E301K	301	Missense	distal	3	no	32.432	35.192	EPSD	TCGA;ICGC;COSMIC	29.179	Up-regulation
Other_ULK_ULK_ULK1_ST	P09467	FBP1	O75385	ULK1	T298	A302V	302	Missense	distal	4	no	32.432	31.757	EPSD	TCGA;ICGC;COSMIC	29.179	Down-regulation
Other_ULK_ULK_ULK1_ST	P09467	FBP1	O75385	ULK1	T298	K300Q	300	Missense	proximal	2	no	32.432	33.234	EPSD	TCGA;ICGC;COSMIC	29.179	Up-regulation
Other_ULK_ULK_ULK1_ST	P08235	NR3C2	O75385	ULK1	S129	Q122H	122	Missense	distal	-7	no	29.054	29.372	EPSD	TCGA;ICGC;COSMIC	29.179	Gain
Other_ULK_ULK_ULK1_ST	P08235	NR3C2	O75385	ULK1	S129	N123H	123	Missense	distal	-6	no	29.054	32.506	EPSD	TCGA;ICGC;COSMIC	29.179	Gain
Other_ULK_ULK_ULK1_ST	P08235	NR3C2	O75385	ULK1	S168	S168C	168	Missense	central	0	yes	40.670	0.000	EPSD	TCGA;ICGC;COSMIC	29.179	Loss
Other_ULK_ULK_ULK1_ST	P08235	NR3C2	O75385	ULK1	S168	G169R	169	Missense	proximal	1	no	40.670	40.687	EPSD	TCGA;ICGC;COSMIC	29.179	Up-regulation
Other_ULK_ULK_ULK1_ST	P08235	NR3C2	O75385	ULK1	S168	V172M	172	Missense	distal	4	no	40.670	41.523	EPSD	TCGA;ICGC;COSMIC	29.179	Up-regulation
Other_ULK_ULK_ULK1_ST	P08235	NR3C2	O75385	ULK1	S168	R162I	162	Missense	distal	-6	no	40.670	39.281	EPSD	TCGA;ICGC	29.179	Down-regulation
Other_ULK_ULK_ULK1_ST	P08235	NR3C2	O75385	ULK1	S238	S238F	238	Missense	central	0	yes	38.146	0.000	EPSD	TCGA;ICGC;COSMIC	29.179	Loss
Other_ULK_ULK_ULK1_ST	P08235	NR3C2	O75385	ULK1	S238	R244Q	244	Missense	distal	6	no	38.146	38.574	EPSD	TCGA;ICGC	29.179	Up-regulation
Other_ULK_ULK_ULK1_ST	P08235	NR3C2	O75385	ULK1	S248	S246C	246	Missense	proximal	-2	no	29.999	18.135	EPSD	TCGA;ICGC;COSMIC	29.179	Loss
Other_ULK_ULK_ULK1_ST	P08235	NR3C2	O75385	ULK1	S248	P251H	251	Missense	distal	3	no	29.999	27.108	EPSD	TCGA;ICGC;COSMIC	29.179	Loss
Other_ULK_ULK_ULK1_ST	P08235	NR3C2	O75385	ULK1	S248	R247K	247	Missense	proximal	-1	no	29.999	29.463	EPSD	TCGA;ICGC;COSMIC	29.179	Down-regulation
Other_ULK_ULK_ULK1_ST	P08235	NR3C2	O75385	ULK1	S248	R244Q	244	Missense	distal	-4	no	29.999	28.552	EPSD	TCGA;ICGC	29.179	Loss
Other_ULK_ULK_ULK1_ST	P08235	NR3C2	O75385	ULK1	S266	P264S	264	Missense	proximal	-2	no	27.037	33.097	EPSD	TCGA;ICGC;COSMIC	29.179	Gain
Other_ULK_ULK_ULK1_ST	P08235	NR3C2	O75385	ULK1	S266	S263R	263	Missense	distal	-3	no	27.037	38.476	EPSD	TCGA;ICGC;COSMIC	29.179	Gain
Other_ULK_ULK_ULK1_ST	P08235	NR3C2	O75385	ULK1	S311	V310F	310	Missense	proximal	-1	no	31.527	30.824	EPSD	TCGA;ICGC;COSMIC	29.179	Down-regulation
Other_ULK_ULK_ULK1_ST	P08235	NR3C2	O75385	ULK1	S311	R307K	307	Missense	distal	-4	no	31.527	27.140	EPSD	TCGA;ICGC	29.179	Loss
Other_ULK_ULK_ULK1_ST	P08235	NR3C2	O75385	ULK1	S311	N305D	305	Missense	distal	-6	no	31.527	32.169	EPSD	TCGA;ICGC	29.179	Up-regulation
Other_ULK_ULK_ULK1_ST	P08235	NR3C2	O75385	ULK1	T735	A733V	733	Missense	proximal	-2	no	35.315	31.696	EPSD	TCGA;COSMIC	29.179	Down-regulation
Other_ULK_ULK_ULK1_ST	P08235	NR3C2	O75385	ULK1	T735	V739F	739	Missense	distal	4	no	35.315	34.831	EPSD	TCGA;COSMIC	29.179	Down-regulation
Other_ULK_ULK_ULK1_ST	P08235	NR3C2	O75385	ULK1	T735	M740I	740	Missense	distal	5	no	35.315	37.622	EPSD	TCGA;COSMIC	29.179	Up-regulation
Other_ULK_ULK_ULK1_ST	P08235	NR3C2	O75385	ULK1	T735	V739I	739	Missense	distal	4	no	35.315	35.863	EPSD	TCGA;COSMIC	29.179	Up-regulation
Other_ULK_ULK_ULK1_ST	P08235	NR3C2	O75385	ULK1	T735	L742I	742	Missense	distal	7	no	35.315	35.691	EPSD	TCGA	29.179	Up-regulation
Other_ULK_ULK_ULK1_ST	Q8TEV9	SMCR8	O75385	ULK1	S282	A278T	278	Missense	distal	-4	no	32.005	33.740	EPSD	TCGA;ICGC;COSMIC	29.179	Up-regulation
Other_ULK_ULK_ULK1_ST	Q8TEV9	SMCR8	O75385	ULK1	S282	Q277E	277	Missense	distal	-5	no	32.005	32.480	EPSD	TCGA;ICGC;COSMIC	29.179	Up-regulation
Other_ULK_ULK_ULK1_ST	Q8TEV9	SMCR8	O75385	ULK1	S400	E405K	405	Missense	distal	5	no	42.706	43.615	PhosphoSitePlus;EPSD	TCGA;ICGC;COSMIC;CCLE	29.179	Up-regulation
Other_ULK_ULK_ULK1_ST	Q8TEV9	SMCR8	O75385	ULK1	S400	Q395K	395	Missense	distal	-5	no	42.706	40.126	PhosphoSitePlus;EPSD	TCGA;ICGC;COSMIC	29.179	Down-regulation
Other_ULK_ULK_ULK1_ST	Q8TEV9	SMCR8	O75385	ULK1	S400	P407S	407	Missense	distal	7	no	42.706	42.206	PhosphoSitePlus;EPSD	TCGA;ICGC;COSMIC	29.179	Down-regulation
Other_ULK_ULK_ULK1_ST	Q8TEV9	SMCR8	O75385	ULK1	S447	V443L	443	Missense	distal	-4	no	26.605	29.632	EPSD	TCGA;ICGC	29.179	Gain
Other_ULK_ULK_ULK1_ST	Q8TEV9	SMCR8	O75385	ULK1	S480	T477M	477	Missense	distal	-3	no	15.405	36.552	EPSD	TCGA;ICGC;COSMIC	29.179	Gain
Other_ULK_ULK_ULK1_ST	Q8TEV9	SMCR8	O75385	ULK1	S492	L493F	493	Missense	proximal	1	no	37.994	37.964	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	29.179	Down-regulation
Other_ULK_ULK_ULK1_ST	Q8TEV9	SMCR8	O75385	ULK1	S492	P496S	496	Missense	distal	4	no	37.994	39.096	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	29.179	Up-regulation
Other_ULK_ULK_ULK1_ST	Q8TEV9	SMCR8	O75385	ULK1	S498	L493F	493	Missense	distal	-5	no	33.080	31.349	EPSD	TCGA;ICGC;COSMIC	29.179	Down-regulation
Other_ULK_ULK_ULK1_ST	Q8TEV9	SMCR8	O75385	ULK1	S498	V501G	501	Missense	distal	3	no	33.080	30.489	EPSD	TCGA;ICGC;COSMIC	29.179	Down-regulation
Other_ULK_ULK_ULK1_ST	Q8TEV9	SMCR8	O75385	ULK1	S498	P496S	496	Missense	proximal	-2	no	33.080	39.140	EPSD	TCGA;ICGC;COSMIC	29.179	Up-regulation
Other_ULK_ULK_ULK1_ST	Q8TEV9	SMCR8	O75385	ULK1	S513	S516I	516	Missense	distal	3	no	27.601	31.725	EPSD	TCGA;ICGC	29.179	Gain
Other_ULK_ULK_ULK1_ST	Q8TEV9	SMCR8	O75385	ULK1	S562	S562R	562	Missense	central	0	yes	43.467	0.000	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	29.179	Loss
Other_ULK_ULK_ULK1_ST	Q8TEV9	SMCR8	O75385	ULK1	S562	P564S	564	Missense	proximal	2	no	43.467	44.895	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	29.179	Up-regulation
Other_ULK_ULK_ULK1_ST	Q8TEV9	SMCR8	O75385	ULK1	S606	E608K	608	Missense	proximal	2	no	32.965	32.400	EPSD	TCGA;ICGC	29.179	Down-regulation
Other_ULK_ULK_ULK1_ST	Q8TEV9	SMCR8	O75385	ULK1	S606	A602T	602	Missense	distal	-4	no	32.965	34.699	EPSD	TCGA;ICGC;COSMIC	29.179	Up-regulation
Other_ULK_ULK_ULK1_ST	Q8TEV9	SMCR8	O75385	ULK1	S643	D641N	641	Missense	proximal	-2	no	33.692	33.069	EPSD	TCGA;ICGC	29.179	Down-regulation
Other_ULK_ULK_ULK1_ST	Q8TEV9	SMCR8	O75385	ULK1	T666	R661W	661	Missense	distal	-5	no	40.511	36.605	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC;CCLE	29.179	Down-regulation
Other_ULK_ULK_ULK1_ST	Q8TEV9	SMCR8	O75385	ULK1	T666	K665E	665	Missense	proximal	-1	no	40.511	41.362	EPSD;PhosphoSitePlus	TCGA;ICGC	29.179	Up-regulation
Other_ULK_ULK_ULK1_ST	Q8TEV9	SMCR8	O75385	ULK1	S886	R883H	883	Missense	distal	-3	no	28.927	29.277	EPSD	TCGA;ICGC	29.179	Gain
Other_ULK_ULK_ULK1_ST	Q15436	SEC23A	O75385	ULK1	S150	S154P	154	Missense	distal	4	no	32.746	31.644	EPSD	TCGA;COSMIC	29.179	Down-regulation
Other_ULK_ULK_ULK1_ST	Q15436	SEC23A	O75385	ULK1	S150	Q152H	152	Missense	proximal	2	no	32.746	33.173	EPSD	TCGA;COSMIC	29.179	Up-regulation
Other_ULK_ULK_ULK1_ST	Q15436	SEC23A	O75385	ULK1	S380	F377L	377	Missense	distal	-3	no	24.831	30.631	EPSD	TCGA;COSMIC	29.179	Gain
Other_ULK_ULK_ULK1_ST	Q15436	SEC23A	O75385	ULK1	S567	D564N	564	Missense	distal	-3	no	30.917	26.241	EPSD	TCGA;COSMIC	29.179	Loss
Other_ULK_ULK_ULK1_ST	Q15436	SEC23A	O75385	ULK1	S567	R569K	569	Missense	proximal	2	no	30.917	30.361	EPSD	TCGA;COSMIC	29.179	Down-regulation
Other_ULK_ULK_ULK1_ST	Q15436	SEC23A	O75385	ULK1	S567	F574L	574	Missense	distal	7	no	30.917	30.392	EPSD	TCGA;COSMIC	29.179	Down-regulation
Other_ULK_ULK_ULK1_ST	Q15436	SEC23A	O75385	ULK1	S567	S571L	571	Missense	distal	4	no	30.917	29.693	EPSD	TCGA;COSMIC	29.179	Down-regulation
Other_ULK_ULK_ULK1_ST	Q15436	SEC23A	O75385	ULK1	S567	S566R	566	Missense	proximal	-1	no	30.917	30.389	EPSD	TCGA;COSMIC	29.179	Down-regulation
Other_ULK_ULK_ULK1_ST	Q15436	SEC23A	O75385	ULK1	S588	F589L	589	Missense	proximal	1	no	36.833	36.864	EPSD	TCGA	29.179	Up-regulation
Other_ULK_ULK_ULK1_ST	Q15436	SEC23A	O75385	ULK1	S588	R586I	586	Missense	proximal	-2	no	36.833	34.206	EPSD	TCGA;COSMIC	29.179	Down-regulation
Other_ULK_ULK_ULK1_ST	Q15436	SEC23A	O75385	ULK1	S588	L584S	584	Missense	distal	-4	no	36.833	38.136	EPSD	TCGA	29.179	Up-regulation
Other_ULK_ULK_ULK1_ST	Q15436	SEC23A	O75385	ULK1	S640	R646P	646	Missense	distal	6	no	36.566	36.775	EPSD	TCGA	29.179	Up-regulation
Other_ULK_ULK_ULK1_ST	Q15436	SEC23A	O75385	ULK1	S640	E633D	633	Missense	distal	-7	no	36.566	36.197	EPSD	TCGA;COSMIC	29.179	Down-regulation
Other_ULK_ULK_ULK1_ST	Q15436	SEC23A	O75385	ULK1	S640	R646H	646	Missense	distal	6	no	36.566	37.502	EPSD	TCGA;COSMIC	29.179	Up-regulation
Other_ULK_ULK_ULK1_ST	Q15436	SEC23A	O75385	ULK1	S640	S639I	639	Missense	proximal	-1	no	36.566	35.374	EPSD	TCGA	29.179	Down-regulation
Other_ULK_ULK_ULK1_ST	O75143	ATG13	O75385	ULK1	S43	P45Q	45	Missense	proximal	2	no	27.993	29.391	EPSD	TCGA;ICGC;COSMIC	29.179	Gain
Other_ULK_ULK_ULK1_ST	P08237	PFKM	O75385	ULK1	S400	A404T	404	Missense	distal	4	no	30.003	30.497	EPSD	TCGA;COSMIC	29.179	Up-regulation
Other_ULK_ULK_ULK1_ST	Q15437	SEC23B	O75385	ULK1	S150	Q145E	145	Missense	distal	-5	no	31.701	32.175	EPSD	TCGA;ICGC;COSMIC	29.179	Up-regulation
Other_ULK_ULK_ULK1_ST	Q15437	SEC23B	O75385	ULK1	S150	E149Q	149	Missense	proximal	-1	no	31.701	31.265	EPSD	TCGA;ICGC;COSMIC	29.179	Down-regulation
Other_ULK_ULK_ULK1_ST	Q15437	SEC23B	O75385	ULK1	S154	P159S	159	Missense	distal	5	no	36.350	34.770	EPSD	TCGA;ICGC;COSMIC	29.179	Down-regulation
Other_ULK_ULK_ULK1_ST	Q15437	SEC23B	O75385	ULK1	S154	E149Q	149	Missense	distal	-5	no	36.350	35.875	EPSD	TCGA;ICGC;COSMIC	29.179	Down-regulation
Other_ULK_ULK_ULK1_ST	Q15437	SEC23B	O75385	ULK1	T407	M402V	402	Missense	distal	-5	no	34.319	31.015	EPSD	TCGA;ICGC;COSMIC	29.179	Down-regulation
Other_ULK_ULK_ULK1_ST	Q15437	SEC23B	O75385	ULK1	T407	R401Q	401	Missense	distal	-6	no	34.319	35.729	EPSD	TCGA;ICGC	29.179	Up-regulation
Other_ULK_ULK_ULK1_ST	Q15437	SEC23B	O75385	ULK1	T407	D409N	409	Missense	proximal	2	no	34.319	34.088	EPSD	TCGA;ICGC	29.179	Down-regulation
Other_ULK_ULK_ULK1_ST	Q15437	SEC23B	O75385	ULK1	S490	Y487H	487	Missense	distal	-3	no	14.546	29.736	EPSD	TCGA;ICGC;COSMIC	29.179	Gain
Other_ULK_ULK_ULK1_ST	Q15437	SEC23B	O75385	ULK1	S491	Y487H	487	Missense	distal	-4	no	22.182	29.332	EPSD	TCGA;ICGC;COSMIC	29.179	Gain
Other_ULK_ULK_ULK1_ST	Q15437	SEC23B	O75385	ULK1	T492	Y487H	487	Missense	distal	-5	no	26.396	31.526	EPSD	TCGA;ICGC;COSMIC	29.179	Gain
Other_ULK_ULK_ULK1_ST	Q14457	BECN1	O75385	ULK1	S15	F16L	16	Missense	proximal	1	no	44.157	44.188	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	29.179	Up-regulation
Other_ULK_ULK_ULK1_ST	Q14457	BECN1	O75385	ULK1	S30	R36H	36	Missense	distal	6	no	28.906	29.842	PhosphoSitePlus;EPSD	TCGA;ICGC;COSMIC	29.179	Gain
Other_ULK_ULK_ULK1_ST	Q14457	BECN1	O75385	ULK1	S30	L34M	34	Missense	distal	4	no	28.906	29.452	PhosphoSitePlus;EPSD	TCGA;ICGC	29.179	Gain
Other_ULK_ULK_ULK1_ST	Q14457	BECN1	O75385	ULK1	S414	G411S	411	Missense	distal	-3	no	29.833	27.292	EPSD	TCGA;ICGC;COSMIC	29.179	Loss
Other_ULK_ULK_ULK1_ST	P06733	ENO1	O75385	ULK1	T100	K103N	103	Missense	distal	3	no	34.501	31.451	EPSD	TCGA;ICGC	29.179	Down-regulation
Other_ULK_ULK_ULK1_ST	P06733	ENO1	O75385	ULK1	T100	E96D	96	Missense	distal	-4	no	34.501	37.293	EPSD	TCGA;ICGC;COSMIC	29.179	Up-regulation
Other_ULK_ULK_ULK1_ST	P06733	ENO1	O75385	ULK1	S104	N109S	109	Missense	distal	5	no	32.418	31.116	EPSD	TCGA;ICGC;COSMIC	29.179	Down-regulation
Other_ULK_ULK_ULK1_ST	P06733	ENO1	O75385	ULK1	S104	K103N	103	Missense	proximal	-1	no	32.418	32.706	EPSD	TCGA;ICGC	29.179	Up-regulation
Other_ULK_ULK_ULK1_ST	P06733	ENO1	O75385	ULK1	S115	N109S	109	Missense	distal	-6	no	42.919	44.193	PhosphoSitePlus;EPSD	TCGA;ICGC;COSMIC	29.179	Up-regulation
Other_ULK_ULK_ULK1_ST	P06733	ENO1	O75385	ULK1	S115	L112V	112	Missense	distal	-3	no	42.919	37.385	PhosphoSitePlus;EPSD	TCGA;ICGC;COSMIC	29.179	Down-regulation
Other_ULK_ULK_ULK1_ST	P06733	ENO1	O75385	ULK1	S115	G113W	113	Missense	proximal	-2	no	42.919	34.316	PhosphoSitePlus;EPSD	TCGA;ICGC;COSMIC	29.179	Down-regulation
Other_ULK_ULK_ULK1_ST	P06733	ENO1	O75385	ULK1	S282	L279M	279	Missense	distal	-3	no	39.464	48.639	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	29.179	Up-regulation
Other_ULK_ULK_ULK1_ST	P06733	ENO1	O75385	ULK1	S353	A356V	356	Missense	distal	3	no	34.369	34.014	EPSD	TCGA;ICGC	29.179	Down-regulation
Other_ULK_ULK_ULK1_ST	Q8NFG4	FLCN	O75385	ULK1	S62	S62R	62	Missense	central	0	yes	32.991	0.000	EPSD	TCGA	29.179	Loss
Other_ULK_ULK_ULK1_ST	Q8NFG4	FLCN	O75385	ULK1	S62	S62I	62	Missense	central	0	yes	32.991	0.000	EPSD	TCGA;ICGC;COSMIC	29.179	Loss
Other_ULK_ULK_ULK1_ST	Q8NFG4	FLCN	O75385	ULK1	S62	E65Q	65	Missense	distal	3	no	32.991	32.748	EPSD	TCGA;ICGC;COSMIC	29.179	Down-regulation
Other_ULK_ULK_ULK1_ST	Q8NFG4	FLCN	O75385	ULK1	S62	R57Q	57	Missense	distal	-5	no	32.991	35.122	EPSD	TCGA;ICGC;COSMIC;GDSC;CCLE	29.179	Up-regulation
Other_ULK_ULK_ULK1_ST	Q8NFG4	FLCN	O75385	ULK1	S331	P326Q	326	Missense	distal	-5	no	25.537	29.660	EPSD	TCGA;ICGC;COSMIC	29.179	Gain
Other_ULK_ULK_ULK1_ST	Q8NFG4	FLCN	O75385	ULK1	S331	P326S	326	Missense	distal	-5	no	25.537	29.198	EPSD	TCGA;ICGC;COSMIC	29.179	Gain
Other_ULK_ULK_ULK1_ST	Q8NFG4	FLCN	O75385	ULK1	T568	S575L	575	Missense	distal	7	no	33.544	34.028	EPSD	TCGA;ICGC;COSMIC	29.179	Up-regulation
Other_ULK_ULK_ULK1_ST	Q8NFG4	FLCN	O75385	ULK1	T568	Y561F	561	Missense	distal	-7	no	33.544	33.288	EPSD	TCGA;ICGC;COSMIC	29.179	Down-regulation
Other_ULK_ULK_ULK1_ST	Q8IVP5	FUNDC1	O75385	ULK1	S17	Y11D	11	Missense	distal	-6	no	38.087	42.700	PhosphoSitePlus	TCGA;ICGC;COSMIC	29.179	Up-regulation
Other_ULK_ULK_ULK1_ST	Q8IVP5	FUNDC1	O75385	ULK1	S17	D16N	16	Missense	proximal	-1	no	38.087	38.378	PhosphoSitePlus	TCGA;ICGC;COSMIC	29.179	Up-regulation
Other_ULK_ULK_ULK1_ST	Q8TDY2	RB1CC1	O75385	ULK1	T61	R58T	58	Missense	distal	-3	no	33.797	24.194	EPSD	TCGA;ICGC;COSMIC;GDSC	29.179	Loss
Other_ULK_ULK_ULK1_ST	Q8TDY2	RB1CC1	O75385	ULK1	T61	D67Y	67	Missense	distal	6	no	33.797	32.520	EPSD	TCGA;ICGC;COSMIC	29.179	Down-regulation
Other_ULK_ULK_ULK1_ST	Q8TDY2	RB1CC1	O75385	ULK1	S222	E227Q	227	Missense	distal	5	no	40.072	41.170	EPSD	TCGA;ICGC;COSMIC	29.179	Up-regulation
Other_ULK_ULK_ULK1_ST	Q8TDY2	RB1CC1	O75385	ULK1	S222	R219K	219	Missense	distal	-3	no	40.072	33.784	EPSD	TCGA;ICGC;COSMIC	29.179	Down-regulation
Other_ULK_ULK_ULK1_ST	Q8TDY2	RB1CC1	O75385	ULK1	S222	D228Y	228	Missense	distal	6	no	40.072	38.795	EPSD	TCGA;ICGC	29.179	Down-regulation
Other_ULK_ULK_ULK1_ST	Q8TDY2	RB1CC1	O75385	ULK1	S237	R236I	236	Missense	proximal	-1	no	35.274	34.609	EPSD	TCGA;ICGC;COSMIC	29.179	Down-regulation
Other_ULK_ULK_ULK1_ST	Q8TDY2	RB1CC1	O75385	ULK1	S281	V286A	286	Missense	distal	5	no	32.407	32.486	EPSD	TCGA;ICGC;COSMIC	29.179	Up-regulation
Other_ULK_ULK_ULK1_ST	Q8TDY2	RB1CC1	O75385	ULK1	S281	E280K	280	Missense	proximal	-1	no	32.407	31.556	EPSD	TCGA;ICGC;COSMIC	29.179	Down-regulation
Other_ULK_ULK_ULK1_ST	Q8TDY2	RB1CC1	O75385	ULK1	S629	S629A	629	Missense	central	0	yes	29.418	0.000	EPSD	TCGA;ICGC;COSMIC	29.179	Loss
Other_ULK_ULK_ULK1_ST	Q8TDY2	RB1CC1	O75385	ULK1	T631	S629A	629	Missense	proximal	-2	no	40.590	35.069	EPSD	TCGA;ICGC;COSMIC	29.179	Down-regulation
Other_ULK_ULK_ULK1_ST	Q8TDY2	RB1CC1	O75385	ULK1	S644	S650C	650	Missense	distal	6	no	29.276	28.195	EPSD	TCGA;ICGC;COSMIC	29.179	Loss
Other_ULK_ULK_ULK1_ST	Q8TDY2	RB1CC1	O75385	ULK1	S644	Q639K	639	Missense	distal	-5	no	29.276	26.696	EPSD	TCGA;ICGC;COSMIC	29.179	Loss
Other_ULK_ULK_ULK1_ST	Q8TDY2	RB1CC1	O75385	ULK1	S644	S647P	647	Missense	distal	3	no	29.276	32.929	EPSD	TCGA;ICGC;COSMIC	29.179	Up-regulation
Other_ULK_ULK_ULK1_ST	Q8TDY2	RB1CC1	O75385	ULK1	S1222	D1215H	1215	Missense	distal	-7	no	29.966	30.957	EPSD	TCGA;ICGC;COSMIC	29.179	Up-regulation
Other_ULK_ULK_ULK1_ST	Q8TDY2	RB1CC1	O75385	ULK1	S1222	Q1229R	1229	Missense	distal	7	no	29.966	29.868	EPSD	TCGA;ICGC;COSMIC	29.179	Down-regulation
Other_ULK_ULK_ULK1_ST	Q8TDY2	RB1CC1	O75385	ULK1	S1284	S1279F	1279	Missense	distal	-5	no	31.374	27.833	EPSD	TCGA;ICGC;COSMIC	29.179	Loss
Other_ULK_ULK_ULK1_ST	Q8TDY2	RB1CC1	O75385	ULK1	S1284	L1287S	1287	Missense	distal	3	no	31.374	28.164	EPSD	TCGA;ICGC;COSMIC	29.179	Loss
Other_ULK_ULK_ULK1_ST	Q8TDY2	RB1CC1	O75385	ULK1	S1284	D1283Y	1283	Missense	proximal	-1	no	31.374	31.105	EPSD	TCGA;ICGC;COSMIC	29.179	Down-regulation
Other_ULK_ULK_ULK1_ST	Q8TDY2	RB1CC1	O75385	ULK1	S1286	S1279F	1279	Missense	distal	-7	no	42.267	39.345	EPSD	TCGA;ICGC;COSMIC	29.179	Down-regulation
Other_ULK_ULK_ULK1_ST	Q8TDY2	RB1CC1	O75385	ULK1	S1286	L1287S	1287	Missense	proximal	1	no	42.267	42.266	EPSD	TCGA;ICGC;COSMIC	29.179	Down-regulation
Other_ULK_ULK_ULK1_ST	Q8TDY2	RB1CC1	O75385	ULK1	S1286	D1283Y	1283	Missense	distal	-3	no	42.267	33.672	EPSD	TCGA;ICGC;COSMIC	29.179	Down-regulation
Other_ULK_ULK_ULK1_ST	Q8TDY2	RB1CC1	O75385	ULK1	S1323	Q1329R	1329	Missense	distal	6	no	32.559	32.131	PhosphoSitePlus;EPSD	TCGA;ICGC;COSMIC	29.179	Down-regulation
Other_ULK_ULK_ULK1_ST	Q8TDY2	RB1CC1	O75385	ULK1	S1370	R1377C	1377	Missense	distal	7	no	29.155	29.351	EPSD	TCGA;ICGC;COSMIC;GDSC	29.179	Gain
Other_ULK_ULK_ULK1_ST	Q8TDY2	RB1CC1	O75385	ULK1	S1370	R1375Q	1375	Missense	distal	5	no	29.155	29.930	EPSD	TCGA;ICGC;COSMIC	29.179	Gain
Other_ULK_ULK_ULK1_ST	Q8TDY2	RB1CC1	O75385	ULK1	S1370	R1363Q	1363	Missense	distal	-7	no	29.155	29.912	EPSD	TCGA;ICGC;COSMIC	29.179	Gain
Other_ULK_ULK_ULK1_ST	Q8TDY2	RB1CC1	O75385	ULK1	S1400	S1394I	1394	Missense	distal	-6	no	36.290	34.358	EPSD	TCGA;ICGC;COSMIC	29.179	Down-regulation
Other_ULK_ULK_ULK1_ST	Q8TDY2	RB1CC1	O75385	ULK1	S1400	R1393H	1393	Missense	distal	-7	no	36.290	37.366	EPSD	TCGA;ICGC	29.179	Up-regulation
Other_ULK_ULK_ULK1_ST	Q8TDY2	RB1CC1	O75385	ULK1	S1400	P1399H	1399	Missense	proximal	-1	no	36.290	36.580	EPSD	TCGA;ICGC	29.179	Up-regulation
Other_ULK_ULK_ULK1_ST	Q8TDY2	RB1CC1	O75385	ULK1	S1441	M1442I	1442	Missense	proximal	1	no	30.632	30.598	EPSD	TCGA;ICGC;COSMIC	29.179	Down-regulation
Other_ULK_ULK_ULK1_ST	Q8TDY2	RB1CC1	O75385	ULK1	S1441	E1439Q	1439	Missense	proximal	-2	no	30.632	32.025	EPSD	TCGA	29.179	Up-regulation
Other_ULK_ULK_ULK1_ST	Q8TDY2	RB1CC1	O75385	ULK1	S1441	E1447K	1447	Missense	distal	6	no	30.632	29.849	EPSD	TCGA;ICGC	29.179	Down-regulation
Other_ULK_ULK_ULK1_ST	Q8TDY2	RB1CC1	O75385	ULK1	S1441	N1448D	1448	Missense	distal	7	no	30.632	30.288	EPSD	TCGA;ICGC;COSMIC	29.179	Down-regulation
Other_ULK_ULK_ULK1_ST	Q8TDY2	RB1CC1	O75385	ULK1	S1484	M1481I	1481	Missense	distal	-3	no	48.604	36.907	EPSD	TCGA;ICGC;COSMIC	29.179	Down-regulation
Other_ULK_ULK_ULK1_ST	O15027	SEC16A	O75385	ULK1	S1905	P1901S	1901	Missense	distal	-4	no	48.132	49.522	EPSD	TCGA;ICGC;COSMIC	29.179	Up-regulation
Other_ULK_ULK_ULK1_ST	O00560	SDCBP	O75385	ULK1	S6	E8K	8	Missense	proximal	2	no	29.653	29.088	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	29.179	Loss
Other_ULK_ULK_ULK1_ST	O00560	SDCBP	O75385	ULK1	S60	R67S	67	Missense	distal	7	no	33.060	32.558	PhosphoSitePlus;EPSD	TCGA;ICGC;COSMIC	29.179	Down-regulation
Other_ULK_ULK_ULK1_ST	O00560	SDCBP	O75385	ULK1	S60	R67C	67	Missense	distal	7	no	33.060	33.256	PhosphoSitePlus;EPSD	TCGA;ICGC;COSMIC	29.179	Up-regulation
Other_ULK_ULK_ULK1_ST	O00560	SDCBP	O75385	ULK1	S60	R67H	67	Missense	distal	7	no	33.060	32.722	PhosphoSitePlus;EPSD	TCGA;ICGC;COSMIC	29.179	Down-regulation
Other_ULK_ULK_ULK1_ST	O00560	SDCBP	O75385	ULK1	S60	L53F	53	Missense	distal	-7	no	33.060	32.519	PhosphoSitePlus;EPSD	TCGA;ICGC	29.179	Down-regulation
Other_ULK_ULK_ULK1_ST	O00560	SDCBP	O75385	ULK1	T206	V209I	209	Missense	distal	3	no	33.749	33.933	EPSD	TCGA;COSMIC	29.179	Up-regulation
Other_ULK_ULK_ULK1_ST	O00560	SDCBP	O75385	ULK1	S285	I278T	278	Missense	distal	-7	no	42.351	44.463	EPSD	TCGA;ICGC;COSMIC	29.179	Up-regulation
Other_ULK_ULK_ULK1_ST	O00560	SDCBP	O75385	ULK1	S285	R281W	281	Missense	distal	-4	no	42.351	37.217	EPSD	TCGA;COSMIC	29.179	Down-regulation
Other_ULK_ULK_ULK1_ST	O00560	SDCBP	O75385	ULK1	S289	T294I	294	Missense	distal	5	no	50.554	51.457	EPSD	TCGA;ICGC;COSMIC	29.179	Up-regulation
Other_ULK_ULK_ULK1_ST	O00560	SDCBP	O75385	ULK1	T294	T294I	294	Missense	central	0	yes	42.852	0.000	EPSD	TCGA;ICGC;COSMIC	29.179	Loss
Other_ULK_ULK_ULK1_ST	Q9Y4P1	ATG4B	O75385	ULK1	S44	S44Y	44	Missense	central	0	yes	41.346	0.000	EPSD	TCGA;ICGC;COSMIC	29.179	Loss
Other_ULK_ULK_ULK1_ST	Q9Y4P1	ATG4B	O75385	ULK1	S316	F322L	322	Missense	distal	6	no	41.974	42.447	PhosphoSitePlus	TCGA;COSMIC	29.179	Up-regulation
Other_ULK_ULK_ULK1_ST	Q9Y4P1	ATG4B	O75385	ULK1	S316	A318T	318	Missense	proximal	2	no	41.974	42.410	PhosphoSitePlus	TCGA;COSMIC	29.179	Up-regulation
Other_ULK_ULK_ULK1_ST	Q9Y4P1	ATG4B	O75385	ULK1	S316	A311V	311	Missense	distal	-5	no	41.974	42.502	PhosphoSitePlus	TCGA;COSMIC	29.179	Up-regulation
Other_ULK_ULK_ULK1_ST	Q8NEB9	PIK3C3	O75385	ULK1	S165	S164I	164	Missense	proximal	-1	no	32.357	31.164	EPSD	TCGA;ICGC;COSMIC	29.179	Down-regulation
Other_ULK_ULK_ULK1_ST	Q8NEB9	PIK3C3	O75385	ULK1	S165	D170N	170	Missense	distal	5	no	32.357	32.737	EPSD	TCGA;COSMIC	29.179	Up-regulation
Other_ULK_ULK_ULK1_ST	Q8NEB9	PIK3C3	O75385	ULK1	S207	M203I	203	Missense	distal	-4	no	47.872	45.220	EPSD	TCGA;COSMIC	29.179	Down-regulation
Other_ULK_ULK_ULK1_ST	Q8NEB9	PIK3C3	O75385	ULK1	S207	S207R	207	Missense	central	0	yes	47.872	0.000	EPSD	TCGA	29.179	Loss
Other_ULK_ULK_ULK1_ST	Q8NEB9	PIK3C3	O75385	ULK1	S207	R210Q	210	Missense	distal	3	no	47.872	50.604	EPSD	TCGA;COSMIC	29.179	Up-regulation
Other_ULK_ULK_ULK1_ST	Q8NEB9	PIK3C3	O75385	ULK1	S207	N213Y	213	Missense	distal	6	no	47.872	46.714	EPSD	TCGA;COSMIC	29.179	Down-regulation
Other_ULK_ULK_ULK1_ST	Q8NEB9	PIK3C3	O75385	ULK1	S243	P245L	245	Missense	proximal	2	no	28.940	29.438	EPSD	TCGA;COSMIC	29.179	Gain
Other_ULK_ULK_ULK1_ST	Q8NEB9	PIK3C3	O75385	ULK1	S261	P256T	256	Missense	distal	-5	no	29.432	32.360	EPSD	TCGA;COSMIC	29.179	Up-regulation
Other_ULK_ULK_ULK1_ST	Q8NEB9	PIK3C3	O75385	ULK1	S261	P258L	258	Missense	distal	-3	no	29.432	39.163	EPSD	TCGA;COSMIC	29.179	Up-regulation
Other_ULK_ULK_ULK1_ST	Q8NEB9	PIK3C3	O75385	ULK1	S261	E263D	263	Missense	proximal	2	no	29.432	29.353	EPSD	TCGA;ICGC;COSMIC;CCLE	29.179	Down-regulation
Other_ULK_ULK_ULK1_ST	Q8NEB9	PIK3C3	O75385	ULK1	S268	A274P	274	Missense	distal	6	no	31.168	30.943	EPSD	TCGA;ICGC;COSMIC	29.179	Down-regulation
Other_ULK_ULK_ULK1_ST	Q8NEB9	PIK3C3	O75385	ULK1	S268	E263D	263	Missense	distal	-5	no	31.168	28.697	EPSD	TCGA;ICGC;COSMIC;CCLE	29.179	Loss
Other_ULK_ULK_ULK1_ST	Q8NEB9	PIK3C3	O75385	ULK1	T790	G786V	786	Missense	distal	-4	no	42.354	38.103	EPSD	TCGA;COSMIC	29.179	Down-regulation
Other_ULK_ULK_ULK1_ST	A2RUS2	DENND3	O75385	ULK1	S445	V451I	451	Missense	distal	6	no	30.698	31.019	EPSD	TCGA;ICGC;COSMIC	29.179	Up-regulation
Other_ULK_ULK_ULK1_ST	A2RUS2	DENND3	O75385	ULK1	S460	R467M	467	Missense	distal	7	no	30.033	29.729	EPSD	TCGA;ICGC	29.179	Down-regulation
Other_ULK_ULK_ULK1_ST	A2RUS2	DENND3	O75385	ULK1	S460	S460L	460	Missense	central	0	yes	30.033	0.000	EPSD	TCGA;ICGC;COSMIC	29.179	Loss
Other_ULK_ULK_ULK1_ST	A2RUS2	DENND3	O75385	ULK1	S460	S459Y	459	Missense	proximal	-1	no	30.033	28.698	EPSD	TCGA;ICGC	29.179	Loss
Other_ULK_ULK_ULK1_ST	A2RUS2	DENND3	O75385	ULK1	S472	M469V	469	Missense	distal	-3	no	38.985	24.276	PhosphoSitePlus;EPSD	TCGA;ICGC;COSMIC	29.179	Loss
Other_ULK_ULK_ULK1_ST	A2RUS2	DENND3	O75385	ULK1	S472	R467M	467	Missense	distal	-5	no	38.985	42.049	PhosphoSitePlus;EPSD	TCGA;ICGC	29.179	Up-regulation
Other_ULK_ULK_ULK1_ST	A2RUS2	DENND3	O75385	ULK1	S472	V471I	471	Missense	proximal	-1	no	38.985	38.533	PhosphoSitePlus;EPSD	TCGA;ICGC;COSMIC	29.179	Down-regulation
Other_ULK_ULK_ULK1_ST	A2RUS2	DENND3	O75385	ULK1	S472	D478N	478	Missense	distal	6	no	38.985	38.865	PhosphoSitePlus;EPSD	TCGA;ICGC;COSMIC	29.179	Down-regulation
Other_ULK_ULK_ULK1_ST	A2RUS2	DENND3	O75385	ULK1	S490	S490L	490	Missense	central	0	yes	36.893	0.000	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	29.179	Loss
Other_ULK_ULK_ULK1_ST	A2RUS2	DENND3	O75385	ULK1	S490	T494M	494	Missense	distal	4	no	36.893	36.579	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	29.179	Down-regulation
Other_ULK_ULK_ULK1_ST	A2RUS2	DENND3	O75385	ULK1	S490	A497T	497	Missense	distal	7	no	36.893	36.859	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	29.179	Down-regulation
Other_ULK_ULK_ULK1_ST	A2RUS2	DENND3	O75385	ULK1	T494	S490L	490	Missense	distal	-4	no	32.472	31.170	EPSD	TCGA;ICGC;COSMIC	29.179	Down-regulation
Other_ULK_ULK_ULK1_ST	A2RUS2	DENND3	O75385	ULK1	T494	T494M	494	Missense	central	0	yes	32.472	0.000	EPSD	TCGA;ICGC;COSMIC	29.179	Loss
Other_ULK_ULK_ULK1_ST	A2RUS2	DENND3	O75385	ULK1	T494	A497T	497	Missense	distal	3	no	32.472	29.392	EPSD	TCGA;ICGC;COSMIC	29.179	Down-regulation
Other_ULK_ULK_ULK1_ST	A2RUS2	DENND3	O75385	ULK1	T494	G501D	501	Missense	distal	7	no	32.472	32.501	EPSD	TCGA;ICGC;COSMIC	29.179	Up-regulation
Other_ULK_ULK_ULK1_ST	A2RUS2	DENND3	O75385	ULK1	S1175	R1179T	1179	Missense	distal	4	no	29.960	30.318	EPSD	TCGA;ICGC;COSMIC	29.179	Up-regulation
Other_ULK_ULK_ULK1_ST	Q9C0C7	AMBRA1	O75385	ULK1	S635	A638T	638	Missense	distal	3	no	46.392	43.311	PhosphoSitePlus;EPSD	TCGA;COSMIC	29.179	Down-regulation
Other_ULK_ULK_ULK1_ST	Q9C0C7	AMBRA1	O75385	ULK1	S637	A638T	638	Missense	proximal	1	no	30.996	31.010	EPSD	TCGA;COSMIC	29.179	Up-regulation
Other_ULK_ULK_ULK1_ST	Q9C0C7	AMBRA1	O75385	ULK1	S1072	E1067G	1067	Missense	distal	-5	no	29.853	24.500	EPSD	TCGA;COSMIC	29.179	Loss
Other_ULK_ULK_ULK1_ST	Q13045	FLII	O75385	ULK1	S64	T70M	70	Missense	distal	6	no	32.418	32.744	PhosphoSitePlus	TCGA;COSMIC	29.179	Up-regulation
Other_ULK_ULK_ULK1_ST	Q13045	FLII	O75385	ULK1	S64	T69I	69	Missense	distal	5	no	32.418	33.321	PhosphoSitePlus	TCGA;ICGC	29.179	Up-regulation
Other_ULK_ULK_ULK1_ST	Q13045	FLII	O75385	ULK1	S406	A403V	403	Missense	distal	-3	no	26.112	33.747	EPSD	TCGA;ICGC;COSMIC	29.179	Gain
Other_ULK_ULK_ULK1_ST	Q13045	FLII	O75385	ULK1	S436	R431W	431	Missense	distal	-5	no	34.426	30.520	EPSD	TCGA;COSMIC	29.179	Down-regulation
Other_ULK_ULK_ULK1_ST	Q13045	FLII	O75385	ULK1	S436	R432K	432	Missense	distal	-4	no	34.426	30.038	EPSD	TCGA;COSMIC	29.179	Down-regulation
Other_ULK_ULK_ULK1_ST	Q13045	FLII	O75385	ULK1	S436	D440G	440	Missense	distal	4	no	34.426	33.979	EPSD	TCGA	29.179	Down-regulation
Other_ULK_ULK_ULK1_ST	Q13045	FLII	O75385	ULK1	S488	E493K	493	Missense	distal	5	no	41.275	42.184	EPSD	TCGA;COSMIC	29.179	Up-regulation
Other_ULK_ULK_ULK1_ST	Q13045	FLII	O75385	ULK1	S488	T492M	492	Missense	distal	4	no	41.275	40.960	EPSD	TCGA;ICGC;COSMIC	29.179	Down-regulation
Other_ULK_ULK_ULK1_ST	Q13045	FLII	O75385	ULK1	S822	L823P	823	Missense	proximal	1	no	39.142	39.128	EPSD	TCGA;COSMIC	29.179	Down-regulation
Other_ULK_ULK_ULK1_ST	Q13045	FLII	O75385	ULK1	T826	V830A	830	Missense	distal	4	no	28.636	29.311	EPSD	TCGA	29.179	Gain
Other_ULK_ULK_ULK1_ST	Q13045	FLII	O75385	ULK1	T847	D840N	840	Missense	distal	-7	no	31.621	31.090	EPSD	TCGA;COSMIC	29.179	Down-regulation
Other_ULK_ULK_ULK1_ST	Q13045	FLII	O75385	ULK1	T847	Y846S	846	Missense	proximal	-1	no	31.621	32.956	EPSD	TCGA;COSMIC	29.179	Up-regulation
Other_ULK_ULK_ULK1_ST	Q13045	FLII	O75385	ULK1	T847	A852G	852	Missense	distal	5	no	31.621	29.872	EPSD	TCGA;COSMIC	29.179	Down-regulation
Other_ULK_ULK_ULK1_ST	Q13045	FLII	O75385	ULK1	S856	A852G	852	Missense	distal	-4	no	28.540	30.563	EPSD	TCGA;COSMIC	29.179	Gain
Other_ULK_ULK_ULK1_ST	Q13045	FLII	O75385	ULK1	S860	S860F	860	Missense	central	0	yes	33.650	0.000	EPSD	TCGA;COSMIC	29.179	Loss
CMGC_MAPK_JNK_MAPK9_ST	O95140	MFN2	P45984-2	MAPK9	S27	L29P	29	Missense	proximal	2	no	162.281	162.126	PhosphoSitePlus	TCGA;ICGC;COSMIC	140.458	Down-regulation
CMGC_MAPK_JNK_MAPK9_ST	O95140	MFN2	P45984-2	MAPK9	S27	A26T	26	Missense	proximal	-1	no	162.281	162.020	PhosphoSitePlus	TCGA;ICGC	140.458	Down-regulation
CMGC_MAPK_JNK_MAPK9_ST	P40763	STAT3	P45984-2	MAPK9	T118	A122T	122	Missense	distal	4	no	142.719	142.890	EPSD	TCGA;ICGC;COSMIC	140.458	Up-regulation
CMGC_MAPK_JNK_MAPK9_ST	P40763	STAT3	P45984-2	MAPK9	T118	L116P	116	Missense	proximal	-2	no	142.719	143.793	EPSD	TCGA;ICGC;COSMIC	140.458	Up-regulation
CMGC_MAPK_JNK_MAPK9_ST	P40763	STAT3	P45984-2	MAPK9	T118	R114H	114	Missense	distal	-4	no	142.719	141.079	EPSD	TCGA;ICGC	140.458	Down-regulation
CMGC_MAPK_JNK_MAPK9_ST	P40763	STAT3	P45984-2	MAPK9	T236	A241D	241	Missense	distal	5	no	142.300	142.853	EPSD	TCGA;COSMIC	140.458	Up-regulation
CMGC_MAPK_JNK_MAPK9_ST	P40763	STAT3	P45984-2	MAPK9	T236	Q232H	232	Missense	distal	-4	no	142.300	139.229	EPSD	TCGA;COSMIC	140.458	Loss
CMGC_MAPK_JNK_MAPK9_ST	P40763	STAT3	P45984-2	MAPK9	T714	S719N	719	Missense	distal	5	no	149.040	148.811	EPSD	TCGA;ICGC	140.458	Down-regulation
CMGC_MAPK_JNK_MAPK9_ST	P40763	STAT3	P45984-2	MAPK9	S727	R729H	729	Missense	proximal	2	no	156.513	156.696	PhosphoSitePlus	TCGA;ICGC;COSMIC;GDSC;CCLE	140.458	Up-regulation
CMGC_MAPK_JNK_MAPK9_ST	P40763	STAT3	P45984-2	MAPK9	S727	P725L	725	Missense	proximal	-2	no	156.513	155.438	PhosphoSitePlus	TCGA;ICGC;COSMIC	140.458	Down-regulation
TK_Tec_TEC_Y	Q06187	BTK	P42680	TEC	Y223	K218N	218	Missense	distal	-5	no	353.276	353.678	PhosphoSitePlus	TCGA;ICGC;COSMIC	232.776	Up-regulation
TK_Tec_TEC_Y	Q06187	BTK	P42680	TEC	Y263	P265S	265	Missense	proximal	2	no	221.232	242.642	EPSD	TCGA;ICGC;COSMIC	232.776	Gain
TK_Tec_TEC_Y	Q06187	BTK	P42680	TEC	Y315	A312S	312	Missense	distal	-3	no	255.030	240.243	EPSD	TCGA;ICGC;COSMIC	232.776	Down-regulation
TK_Tec_TEC_Y	Q06187	BTK	P42680	TEC	Y551	D549N	549	Missense	proximal	-2	no	364.283	348.108	EPSD	TCGA;ICGC;COSMIC	232.776	Down-regulation
TK_Tec_TEC_Y	Q08881	ITK	P42680	TEC	Y146	K150N	150	Missense	distal	4	no	284.658	285.234	EPSD	TCGA;ICGC;COSMIC	232.776	Up-regulation
TK_Tec_TEC_Y	Q08881	ITK	P42680	TEC	Y146	T149A	149	Missense	distal	3	no	284.658	306.538	EPSD	TCGA;ICGC;COSMIC	232.776	Up-regulation
TK_Tec_TEC_Y	Q08881	ITK	P42680	TEC	Y180	D181H	181	Missense	proximal	1	no	342.208	343.959	PhosphoSitePlus	TCGA;ICGC;COSMIC	232.776	Up-regulation
TK_Tec_TEC_Y	Q08881	ITK	P42680	TEC	Y180	P187T	187	Missense	distal	7	no	342.208	343.100	PhosphoSitePlus	TCGA;ICGC;COSMIC;GDSC;CCLE	232.776	Up-regulation
TK_Tec_TEC_Y	Q08881	ITK	P42680	TEC	Y180	E173K	173	Missense	distal	-7	no	342.208	342.082	PhosphoSitePlus	TCGA;ICGC;COSMIC	232.776	Down-regulation
TK_Tec_TEC_Y	Q08881	ITK	P42680	TEC	Y180	V175M	175	Missense	distal	-5	no	342.208	343.206	PhosphoSitePlus	TCGA;ICGC	232.776	Up-regulation
TK_Tec_TEC_Y	Q08881	ITK	P42680	TEC	Y512	T516K	516	Missense	distal	4	no	406.594	402.472	EPSD	TCGA;ICGC;COSMIC	232.776	Down-regulation
TK_Tec_TEC_Y	Q08881	ITK	P42680	TEC	Y512	L508Q	508	Missense	distal	-4	no	406.594	408.156	EPSD	TCGA;ICGC;COSMIC	232.776	Up-regulation
TK_Tec_TEC_Y	Q99952	PTPN18	P42680	TEC	Y281	A274T	274	Missense	distal	-7	no	286.893	269.134	PhosphoSitePlus;EPSD	TCGA;ICGC;COSMIC	232.776	Down-regulation
TK_Tec_TEC_Y	Q99952	PTPN18	P42680	TEC	Y281	V288M	288	Missense	distal	7	no	286.893	285.140	PhosphoSitePlus;EPSD	TCGA;ICGC;COSMIC	232.776	Down-regulation
TK_Tec_TEC_Y	Q99952	PTPN18	P42680	TEC	Y281	R282K	282	Missense	proximal	1	no	286.893	286.800	PhosphoSitePlus;EPSD	TCGA;ICGC	232.776	Down-regulation
TK_Tec_TEC_Y	Q99952	PTPN18	P42680	TEC	Y314	A317T	317	Missense	distal	3	no	260.056	238.177	EPSD	TCGA;ICGC;COSMIC	232.776	Down-regulation
TK_Tec_TEC_Y	Q99952	PTPN18	P42680	TEC	Y314	Y314C	314	Missense	central	0	yes	260.056	0.000	EPSD	TCGA;ICGC;COSMIC	232.776	Loss
TK_Tec_TEC_Y	Q99952	PTPN18	P42680	TEC	Y314	D315V	315	Missense	proximal	1	no	260.056	261.323	EPSD	TCGA;ICGC;COSMIC	232.776	Up-regulation
TK_Tec_TEC_Y	Q99952	PTPN18	P42680	TEC	Y354	H348R	348	Missense	distal	-6	no	448.162	454.829	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	232.776	Up-regulation
TK_Tec_TEC_Y	P09038	FGF2	P42680	TEC	Y215	R214L	214	Missense	proximal	-1	no	433.447	435.539	EPSD	TCGA;ICGC	232.776	Up-regulation
TK_Tec_TEC_Y	P09038	FGF2	P42680	TEC	Y215	M218I	218	Missense	distal	3	no	433.447	422.067	EPSD	TCGA;ICGC;COSMIC	232.776	Down-regulation
TK_Tec_TEC_Y	P09038	FGF2	P42680	TEC	Y215	D221Y	221	Missense	distal	6	no	433.447	414.200	EPSD	TCGA;ICGC;COSMIC	232.776	Down-regulation
TK_Tec_TEC_Y	P09038	FGF2	P42680	TEC	Y245	R249Q	249	Missense	distal	4	no	293.041	285.345	EPSD	TCGA;ICGC;COSMIC	232.776	Down-regulation
TK_Tec_TEC_Y	P09038	FGF2	P42680	TEC	Y257	Y257F	257	Missense	central	0	yes	352.187	0.000	EPSD	TCGA;ICGC;COSMIC	232.776	Loss
TK_Tec_TEC_Y	P09038	FGF2	P42680	TEC	Y257	R262Q	262	Missense	distal	5	no	352.187	356.577	EPSD	TCGA;ICGC;COSMIC;GDSC	232.776	Up-regulation
TK_Tec_TEC_Y	P51813	BMX	P42680	TEC	Y202	K199N	199	Missense	distal	-3	no	353.268	367.942	EPSD	TCGA;ICGC;COSMIC	232.776	Up-regulation
TK_Tec_TEC_Y	P51813	BMX	P42680	TEC	Y202	Q205K	205	Missense	distal	3	no	353.268	348.193	EPSD	TCGA;ICGC;COSMIC	232.776	Down-regulation
TK_Tec_TEC_Y	P51813	BMX	P42680	TEC	Y202	P206A	206	Missense	distal	4	no	353.268	378.180	EPSD	TCGA;ICGC;COSMIC	232.776	Up-regulation
TK_Tec_TEC_Y	P51813	BMX	P42680	TEC	Y202	N201H	201	Missense	proximal	-1	no	353.268	356.130	EPSD	TCGA;ICGC;COSMIC	232.776	Up-regulation
TK_Tec_TEC_Y	P51813	BMX	P42680	TEC	Y216	Y216H	216	Missense	central	0	yes	389.832	0.000	PhosphoSitePlus	TCGA;ICGC;COSMIC	232.776	Loss
TK_Tec_TEC_Y	P51813	BMX	P42680	TEC	Y566	D563H	563	Missense	distal	-3	no	380.532	332.057	EPSD	TCGA;ICGC;COSMIC	232.776	Down-regulation
TK_Tec_TEC_Y	P51813	BMX	P42680	TEC	Y566	L562I	562	Missense	distal	-4	no	380.532	378.818	EPSD	TCGA;ICGC;COSMIC	232.776	Down-regulation
TK_Tec_TEC_Y	P42680	TEC	P42680	TEC	Y188	V184I	184	Missense	distal	-4	no	330.850	326.782	EPSD	TCGA;ICGC;COSMIC	232.776	Down-regulation
TK_Tec_TEC_Y	P42680	TEC	P42680	TEC	Y188	V185I	185	Missense	distal	-3	no	330.850	326.154	EPSD	TCGA;ICGC;COSMIC	232.776	Down-regulation
TK_Tec_TEC_Y	P42680	TEC	P42680	TEC	Y188	E181K	181	Missense	distal	-7	no	330.850	330.723	EPSD	TCGA;ICGC;COSMIC	232.776	Down-regulation
TK_Tec_TEC_Y	P42680	TEC	P42680	TEC	Y206	E201K	201	Missense	distal	-5	no	247.841	246.337	PhosphoSitePlus	TCGA;ICGC;COSMIC	232.776	Down-regulation
TK_Tec_TEC_Y	P42680	TEC	P42680	TEC	Y206	K211N	211	Missense	distal	5	no	247.841	251.865	PhosphoSitePlus	TCGA;ICGC;COSMIC	232.776	Up-regulation
TK_Tec_TEC_Y	P42680	TEC	P42680	TEC	Y513	M510I	510	Missense	distal	-3	no	302.507	282.784	EPSD	TCGA;ICGC;COSMIC	232.776	Down-regulation
TK_Tec_TEC_Y	P42680	TEC	P42680	TEC	Y519	S522A	522	Missense	distal	3	no	424.813	439.863	EPSD	TCGA;ICGC;COSMIC	232.776	Up-regulation
Other_TLK_TLK1_ST	Q99638	RAD9A	Q9UKI8	TLK1	S270	S266L	266	Missense	distal	-4	no	2.666	2.054	EPSD	TCGA;ICGC;COSMIC;GDSC;CCLE	2.233	Loss
Other_TLK_TLK1_ST	Q99638	RAD9A	Q9UKI8	TLK1	S270	D274N	274	Missense	distal	4	no	2.666	2.799	EPSD	TCGA;ICGC;COSMIC;GDSC;CCLE	2.233	Up-regulation
Other_TLK_TLK1_ST	Q99638	RAD9A	Q9UKI8	TLK1	S324	R320W	320	Missense	distal	-4	no	2.058	2.388	EPSD	TCGA;ICGC;COSMIC	2.233	Gain
Other_TLK_TLK1_ST	Q96PY6	NEK1	Q9UKI8	TLK1	S14	G16E	16	Missense	proximal	2	no	6.636	6.683	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	2.233	Up-regulation
Other_TLK_TLK1_ST	Q96PY6	NEK1	Q9UKI8	TLK1	S14	Q8H	8	Missense	distal	-6	no	6.636	6.630	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	2.233	Down-regulation
Other_TLK_TLK1_ST	Q96PY6	NEK1	Q9UKI8	TLK1	T141	D139N	139	Missense	proximal	-2	no	6.257	6.149	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	2.233	Down-regulation
Other_TLK_TLK1_ST	Q96PY6	NEK1	Q9UKI8	TLK1	T141	G148E	148	Missense	distal	7	no	6.257	6.001	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	2.233	Down-regulation
Other_TLK_TLK1_ST	Q96PY6	NEK1	Q9UKI8	TLK1	T141	V142E	142	Missense	proximal	1	no	6.257	6.255	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	2.233	Down-regulation
CMGC_CDK_CDC2_CDK1_ST	Q13049	TRIM32	P06493	CDK1	S328	R323T	323	Missense	distal	-5	no	3.556	3.496	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	3.158	Down-regulation
CMGC_CDK_CDC2_CDK1_ST	Q13049	TRIM32	P06493	CDK1	S339	R344W	344	Missense	distal	5	no	3.220	3.333	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC;GDSC	3.158	Up-regulation
CMGC_CDK_CDC2_CDK1_ST	Q13049	TRIM32	P06493	CDK1	S339	R344Q	344	Missense	distal	5	no	3.220	3.244	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	3.158	Up-regulation
CMGC_CDK_CDC2_CDK1_ST	Q13049	TRIM32	P06493	CDK1	S339	P340S	340	Missense	proximal	1	no	3.220	0.036	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	3.158	Loss
CMGC_CDK_CDC2_CDK1_ST	O15151	MDM4	P06493	CDK1	S20	Q26E	26	Missense	distal	6	no	3.656	3.646	EPSD	TCGA;ICGC;COSMIC	3.158	Down-regulation
CMGC_CDK_CDC2_CDK1_ST	O15151	MDM4	P06493	CDK1	S20	R18S	18	Missense	proximal	-2	no	3.656	3.589	EPSD	TCGA;ICGC	3.158	Down-regulation
CMGC_CDK_CDC2_CDK1_ST	P11388	TOP2A	P06493	CDK1	S4	E2K	2	Missense	proximal	-2	no	3.479	3.507	EPSD	TCGA	3.158	Up-regulation
CMGC_CDK_CDC2_CDK1_ST	P11388	TOP2A	P06493	CDK1	S4	P5L	5	Missense	proximal	1	no	3.479	-0.208	EPSD	TCGA;ICGC;COSMIC	3.158	Loss
CMGC_CDK_CDC2_CDK1_ST	P11388	TOP2A	P06493	CDK1	S1247	E1245K	1245	Missense	proximal	-2	no	3.447	3.476	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	3.158	Up-regulation
CMGC_CDK_CDC2_CDK1_ST	P11388	TOP2A	P06493	CDK1	S1247	E1242G	1242	Missense	distal	-5	no	3.447	3.519	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	3.158	Up-regulation
CMGC_CDK_CDC2_CDK1_ST	P11388	TOP2A	P06493	CDK1	S1247	E1242D	1242	Missense	distal	-5	no	3.447	3.438	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	3.158	Down-regulation
CMGC_CDK_CDC2_CDK1_ST	Q99638	RAD9A	P06493	CDK1	S380	D386V	386	Missense	distal	6	no	3.427	3.414	EPSD	TCGA;ICGC	3.158	Down-regulation
CMGC_CDK_CDC2_CDK1_ST	P49792	RANBP2	P06493	CDK1	S700	D693H	693	Missense	distal	-7	no	3.234	3.233	EPSD	TCGA;ICGC;COSMIC	3.158	Down-regulation
CMGC_CDK_CDC2_CDK1_ST	P49792	RANBP2	P06493	CDK1	S700	P701S	701	Missense	proximal	1	no	3.234	0.050	EPSD	TCGA;ICGC;COSMIC	3.158	Loss
CMGC_CDK_CDC2_CDK1_ST	P49792	RANBP2	P06493	CDK1	S700	E706A	706	Missense	distal	6	no	3.234	3.266	EPSD	TCGA;ICGC;COSMIC	3.158	Up-regulation
CMGC_CDK_CDC2_CDK1_ST	P49792	RANBP2	P06493	CDK1	T799	P797A	797	Missense	proximal	-2	no	3.203	3.210	EPSD	TCGA;ICGC;COSMIC	3.158	Up-regulation
CMGC_CDK_CDC2_CDK1_ST	P49792	RANBP2	P06493	CDK1	T799	K798E	798	Missense	proximal	-1	no	3.203	3.165	EPSD	TCGA;GDSC	3.158	Down-regulation
CMGC_CDK_CDC2_CDK1_ST	P49792	RANBP2	P06493	CDK1	T799	Y795N	795	Missense	distal	-4	no	3.203	3.230	EPSD	TCGA;ICGC;COSMIC	3.158	Up-regulation
CMGC_CDK_CDC2_CDK1_ST	P49792	RANBP2	P06493	CDK1	T799	S792I	792	Missense	distal	-7	no	3.203	3.051	EPSD	TCGA;ICGC;COSMIC	3.158	Loss
CMGC_CDK_CDC2_CDK1_ST	P49792	RANBP2	P06493	CDK1	S955	G958R	958	Missense	distal	3	no	3.102	3.295	EPSD	TCGA;ICGC;COSMIC	3.158	Gain
CMGC_CDK_CDC2_CDK1_ST	P49792	RANBP2	P06493	CDK1	S955	D960G	960	Missense	distal	5	no	3.102	3.196	EPSD	TCGA;ICGC;COSMIC	3.158	Gain
CMGC_CDK_CDC2_CDK1_ST	P49792	RANBP2	P06493	CDK1	S1249	I1242S	1242	Missense	distal	-7	no	3.568	3.720	EPSD	TCGA;ICGC;COSMIC	3.158	Up-regulation
CMGC_CDK_CDC2_CDK1_ST	P49792	RANBP2	P06493	CDK1	T1255	S1260L	1260	Missense	distal	5	no	3.395	3.608	EPSD	TCGA	3.158	Up-regulation
CMGC_CDK_CDC2_CDK1_ST	P49792	RANBP2	P06493	CDK1	T1255	A1258T	1258	Missense	distal	3	no	3.395	3.307	EPSD	TCGA;ICGC;COSMIC	3.158	Down-regulation
CMGC_CDK_CDC2_CDK1_ST	P49792	RANBP2	P06493	CDK1	T1412	A1409T	1409	Missense	distal	-3	no	3.716	3.679	EPSD	TCGA;ICGC;COSMIC	3.158	Down-regulation
CMGC_CDK_CDC2_CDK1_ST	P49792	RANBP2	P06493	CDK1	T1412	E1416K	1416	Missense	distal	4	no	3.716	3.747	EPSD	TCGA	3.158	Up-regulation
CMGC_CDK_CDC2_CDK1_ST	P49792	RANBP2	P06493	CDK1	S1573	P1579T	1579	Missense	distal	6	no	3.199	3.208	EPSD	TCGA;ICGC;COSMIC	3.158	Up-regulation
CMGC_CDK_CDC2_CDK1_ST	P49792	RANBP2	P06493	CDK1	S1573	V1578I	1578	Missense	distal	5	no	3.199	3.213	EPSD	TCGA;ICGC;COSMIC	3.158	Up-regulation
CMGC_CDK_CDC2_CDK1_ST	P49792	RANBP2	P06493	CDK1	T1761	S1764F	1764	Missense	distal	3	no	3.468	3.337	EPSD	TCGA;ICGC;COSMIC	3.158	Down-regulation
CMGC_CDK_CDC2_CDK1_ST	P49792	RANBP2	P06493	CDK1	T1761	S1765L	1765	Missense	distal	4	no	3.468	3.349	EPSD	TCGA;ICGC;COSMIC	3.158	Down-regulation
CMGC_CDK_CDC2_CDK1_ST	P49792	RANBP2	P06493	CDK1	S1869	S1869L	1869	Missense	central	0	yes	3.179	0.000	EPSD	TCGA;ICGC;COSMIC;GDSC;CCLE	3.158	Loss
CMGC_CDK_CDC2_CDK1_ST	P49792	RANBP2	P06493	CDK1	T2128	E2134Q	2134	Missense	distal	6	no	3.509	3.520	EPSD	TCGA;ICGC;COSMIC	3.158	Up-regulation
CMGC_CDK_CDC2_CDK1_ST	P49792	RANBP2	P06493	CDK1	T2128	A2124T	2124	Missense	distal	-4	no	3.509	3.545	EPSD	TCGA;ICGC;COSMIC	3.158	Up-regulation
CMGC_CDK_CDC2_CDK1_ST	P49792	RANBP2	P06493	CDK1	S2280	Q2286H	2286	Missense	distal	6	no	3.534	3.532	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	3.158	Down-regulation
CMGC_CDK_CDC2_CDK1_ST	P49792	RANBP2	P06493	CDK1	S2280	S2278Y	2278	Missense	proximal	-2	no	3.534	3.585	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	3.158	Up-regulation
CMGC_CDK_CDC2_CDK1_ST	P49792	RANBP2	P06493	CDK1	T2387	N2383S	2383	Missense	distal	-4	no	3.318	3.391	EPSD	TCGA;ICGC;COSMIC	3.158	Up-regulation
CMGC_CDK_CDC2_CDK1_ST	P49792	RANBP2	P06493	CDK1	T2387	C2381F	2381	Missense	distal	-6	no	3.318	3.326	EPSD	TCGA;ICGC;COSMIC	3.158	Up-regulation
CMGC_CDK_CDC2_CDK1_ST	P49792	RANBP2	P06493	CDK1	T2450	H2452Y	2452	Missense	proximal	2	no	3.386	3.391	EPSD	TCGA;ICGC;COSMIC	3.158	Up-regulation
CMGC_CDK_CDC2_CDK1_ST	P49792	RANBP2	P06493	CDK1	T2450	D2446Y	2446	Missense	distal	-4	no	3.386	3.345	EPSD	TCGA;ICGC;COSMIC	3.158	Down-regulation
CMGC_CDK_CDC2_CDK1_ST	P49792	RANBP2	P06493	CDK1	T2504	P2505L	2505	Missense	proximal	1	no	3.196	-0.490	EPSD	TCGA;ICGC;COSMIC	3.158	Loss
CMGC_CDK_CDC2_CDK1_ST	P49792	RANBP2	P06493	CDK1	T2504	A2507S	2507	Missense	distal	3	no	3.196	3.143	EPSD	TCGA;ICGC;COSMIC	3.158	Loss
CMGC_CDK_CDC2_CDK1_ST	P49792	RANBP2	P06493	CDK1	S2510	P2505L	2505	Missense	distal	-5	no	3.052	3.173	EPSD	TCGA;ICGC;COSMIC	3.158	Gain
CMGC_CDK_CDC2_CDK1_ST	P49792	RANBP2	P06493	CDK1	T2613	I2607M	2607	Missense	distal	-6	no	3.749	3.736	EPSD	TCGA;ICGC;COSMIC	3.158	Down-regulation
CMGC_CDK_CDC2_CDK1_ST	P49792	RANBP2	P06493	CDK1	S2804	S2805P	2805	Missense	proximal	1	no	0.174	3.359	EPSD	TCGA;ICGC;COSMIC	3.158	Gain
CMGC_CDK_CDC2_CDK1_ST	P49792	RANBP2	P06493	CDK1	S3207	I3202T	3202	Missense	distal	-5	no	3.646	3.515	EPSD	TCGA;ICGC;COSMIC	3.158	Down-regulation
CMGC_CDK_CDC2_CDK1_ST	P49792	RANBP2	P06493	CDK1	S3207	E3203Q	3203	Missense	distal	-4	no	3.646	3.658	EPSD	TCGA;ICGC;COSMIC	3.158	Up-regulation
CMGC_CDK_CDC2_CDK1_ST	P49792	RANBP2	P06493	CDK1	S3207	R3214Q	3214	Missense	distal	7	no	3.646	3.642	EPSD	TCGA;ICGC;COSMIC	3.158	Down-regulation
CMGC_CDK_CDC2_CDK1_ST	P30291	WEE1	P06493	CDK1	S472	P473L	473	Missense	proximal	1	no	3.226	-0.460	EPSD	TCGA;ICGC;COSMIC	3.158	Loss
CMGC_CDK_CDC2_CDK1_ST	Q07820	MCL1	P06493	CDK1	S121	E123K	123	Missense	proximal	2	no	3.429	3.424	EPSD	TCGA;ICGC;COSMIC	3.158	Down-regulation
CMGC_CDK_CDC2_CDK1_ST	Q07820	MCL1	P06493	CDK1	T163	S162W	162	Missense	proximal	-1	no	3.054	3.188	EPSD	TCGA;ICGC;COSMIC	3.158	Gain
CMGC_CDK_CDC2_CDK1_ST	Q14980	NUMA1	P06493	CDK1	S112	H105N	105	Missense	distal	-7	no	3.226	3.228	EPSD	TCGA;ICGC;COSMIC	3.158	Up-regulation
CMGC_CDK_CDC2_CDK1_ST	Q14980	NUMA1	P06493	CDK1	S112	F119L	119	Missense	distal	7	no	3.226	3.234	EPSD	TCGA;ICGC;COSMIC	3.158	Up-regulation
CMGC_CDK_CDC2_CDK1_ST	Q14980	NUMA1	P06493	CDK1	S200	S198L	198	Missense	proximal	-2	no	3.131	3.178	EPSD	TCGA;ICGC;COSMIC	3.158	Gain
CMGC_CDK_CDC2_CDK1_ST	Q14980	NUMA1	P06493	CDK1	S203	S198L	198	Missense	distal	-5	no	3.170	3.314	EPSD	TCGA;ICGC;COSMIC	3.158	Up-regulation
CMGC_CDK_CDC2_CDK1_ST	Q14980	NUMA1	P06493	CDK1	S203	P204H	204	Missense	proximal	1	no	3.170	0.486	EPSD	TCGA;ICGC;COSMIC	3.158	Loss
CMGC_CDK_CDC2_CDK1_ST	Q14980	NUMA1	P06493	CDK1	S203	D207N	207	Missense	distal	4	no	3.170	3.197	EPSD	TCGA;ICGC;COSMIC	3.158	Up-regulation
CMGC_CDK_CDC2_CDK1_ST	Q14980	NUMA1	P06493	CDK1	S271	A269T	269	Missense	proximal	-2	no	3.143	3.223	EPSD	TCGA;ICGC;COSMIC	3.158	Gain
CMGC_CDK_CDC2_CDK1_ST	Q14980	NUMA1	P06493	CDK1	S1225	L1226P	1226	Missense	proximal	1	no	-0.045	3.641	EPSD	TCGA;ICGC;COSMIC	3.158	Gain
CMGC_CDK_CDC2_CDK1_ST	Q14980	NUMA1	P06493	CDK1	T1776	R1781W	1781	Missense	distal	5	no	3.052	3.164	EPSD	TCGA;COSMIC	3.158	Gain
CMGC_CDK_CDC2_CDK1_ST	Q14980	NUMA1	P06493	CDK1	T2106	A2105V	2105	Missense	proximal	-1	no	3.671	3.871	EPSD;PhosphoSitePlus	TCGA;COSMIC	3.158	Up-regulation
CMGC_CDK_CDC2_CDK1_ST	Q14980	NUMA1	P06493	CDK1	T2106	A2102V	2102	Missense	distal	-4	no	3.671	3.577	EPSD;PhosphoSitePlus	TCGA;COSMIC	3.158	Down-regulation
CMGC_CDK_CDC2_CDK1_ST	Q96FF9	CDCA5	P06493	CDK1	S21	S15C	15	Missense	distal	-6	no	3.327	3.344	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	3.158	Up-regulation
CMGC_CDK_CDC2_CDK1_ST	Q96FF9	CDCA5	P06493	CDK1	S79	S75L	75	Missense	distal	-4	no	3.218	3.024	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	3.158	Loss
CMGC_CDK_CDC2_CDK1_ST	Q96FF9	CDCA5	P06493	CDK1	S154	E150Q	150	Missense	distal	-4	no	3.197	3.209	EPSD	TCGA;ICGC;COSMIC	3.158	Up-regulation
CMGC_CDK_CDC2_CDK1_ST	Q96FF9	CDCA5	P06493	CDK1	S154	S156C	156	Missense	proximal	2	no	3.197	3.211	EPSD	TCGA;ICGC;COSMIC	3.158	Up-regulation
CMGC_CDK_CDC2_CDK1_ST	Q96FF9	CDCA5	P06493	CDK1	S154	T151I	151	Missense	distal	-3	no	3.197	3.152	EPSD	TCGA;ICGC	3.158	Loss
CMGC_CDK_CDC2_CDK1_ST	Q96FF9	CDCA5	P06493	CDK1	S154	S158F	158	Missense	distal	4	no	3.197	3.101	EPSD	TCGA;ICGC;COSMIC	3.158	Loss
CMGC_CDK_CDC2_CDK1_ST	P10636	MAPT	P06493	CDK1	T498	P493Q	493	Missense	distal	-5	no	3.296	3.299	EPSD	TCGA;COSMIC	3.158	Up-regulation
CMGC_CDK_CDC2_CDK1_ST	Q99728	BARD1	P06493	CDK1	S288	E284D	284	Missense	distal	-4	no	3.330	3.332	EPSD;PhosphoSitePlus	TCGA;ICGC	3.158	Up-regulation
CMGC_CDK_CDC2_CDK1_ST	Q99728	BARD1	P06493	CDK1	S288	P281S	281	Missense	distal	-7	no	3.330	3.371	EPSD;PhosphoSitePlus	TCGA;COSMIC;CCLE	3.158	Up-regulation
CMGC_CDK_CDC2_CDK1_ST	Q99728	BARD1	P06493	CDK1	S496	K503T	503	Missense	distal	7	no	3.257	3.251	EPSD	TCGA;ICGC;COSMIC	3.158	Down-regulation
CMGC_CDK_CDC2_CDK1_ST	Q9NXR1	NDE1	P06493	CDK1	T243	R250W	250	Missense	distal	7	no	3.620	3.627	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	3.158	Up-regulation
CMGC_CDK_CDC2_CDK1_ST	Q9NXR1	NDE1	P06493	CDK1	T243	T240A	240	Missense	distal	-3	no	3.620	3.657	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	3.158	Up-regulation
CMGC_CDK_CDC2_CDK1_ST	Q9NXR1	NDE1	P06493	CDK1	T243	L245F	245	Missense	proximal	2	no	3.620	3.619	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	3.158	Down-regulation
CMGC_CDK_CDC2_CDK1_ST	Q9NXR1	NDE1	P06493	CDK1	T243	T246I	246	Missense	distal	3	no	3.620	3.557	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	3.158	Down-regulation
CMGC_CDK_CDC2_CDK1_ST	Q9NXR1	NDE1	P06493	CDK1	T246	R250W	250	Missense	distal	4	no	4.229	4.156	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	3.158	Down-regulation
CMGC_CDK_CDC2_CDK1_ST	Q9NXR1	NDE1	P06493	CDK1	T246	T240A	240	Missense	distal	-6	no	4.229	4.228	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	3.158	Down-regulation
CMGC_CDK_CDC2_CDK1_ST	Q9NXR1	NDE1	P06493	CDK1	T246	L245F	245	Missense	proximal	-1	no	4.229	4.180	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	3.158	Down-regulation
CMGC_CDK_CDC2_CDK1_ST	Q9NXR1	NDE1	P06493	CDK1	T246	T246I	246	Missense	central	0	yes	4.229	0.000	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	3.158	Loss
CMGC_CDK_CDC2_CDK1_ST	P21333	FLNA	P06493	CDK1	S564	E567K	567	Missense	distal	3	no	3.192	3.296	EPSD	TCGA;ICGC;COSMIC	3.158	Up-regulation
CMGC_CDK_CDC2_CDK1_ST	P21333	FLNA	P06493	CDK1	S564	G562W	562	Missense	proximal	-2	no	3.192	3.141	EPSD	TCGA;ICGC;COSMIC	3.158	Loss
CMGC_CDK_CDC2_CDK1_ST	P21333	FLNA	P06493	CDK1	S564	Q559E	559	Missense	distal	-5	no	3.192	3.220	EPSD	TCGA;ICGC;COSMIC	3.158	Up-regulation
CMGC_CDK_CDC2_CDK1_ST	P21333	FLNA	P06493	CDK1	S564	P565L	565	Missense	proximal	1	no	3.192	-0.494	EPSD	TCGA;ICGC;COSMIC	3.158	Loss
CMGC_CDK_CDC2_CDK1_ST	P21333	FLNA	P06493	CDK1	S959	D954Y	954	Missense	distal	-5	no	3.387	3.423	EPSD	TCGA;ICGC;COSMIC	3.158	Up-regulation
CMGC_CDK_CDC2_CDK1_ST	P21333	FLNA	P06493	CDK1	S966	P967S	967	Missense	proximal	1	no	3.404	0.220	EPSD	TCGA;ICGC;COSMIC	3.158	Loss
CMGC_CDK_CDC2_CDK1_ST	P21333	FLNA	P06493	CDK1	S966	F961L	961	Missense	distal	-5	no	3.404	3.438	EPSD	TCGA;ICGC	3.158	Up-regulation
CMGC_CDK_CDC2_CDK1_ST	P21333	FLNA	P06493	CDK1	S1055	P1051H	1051	Missense	distal	-4	no	3.229	3.210	EPSD	TCGA;ICGC;COSMIC	3.158	Down-regulation
CMGC_CDK_CDC2_CDK1_ST	P21333	FLNA	P06493	CDK1	S1055	P1053H	1053	Missense	proximal	-2	no	3.229	3.376	EPSD	TCGA;ICGC	3.158	Up-regulation
CMGC_CDK_CDC2_CDK1_ST	P21333	FLNA	P06493	CDK1	S1084	A1082V	1082	Missense	proximal	-2	no	3.355	3.520	EPSD;PhosphoSitePlus	TCGA;ICGC	3.158	Up-regulation
CMGC_CDK_CDC2_CDK1_ST	P21333	FLNA	P06493	CDK1	S1084	R1087H	1087	Missense	distal	3	no	3.355	3.263	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	3.158	Down-regulation
CMGC_CDK_CDC2_CDK1_ST	P21333	FLNA	P06493	CDK1	S1084	R1087L	1087	Missense	distal	3	no	3.355	3.102	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	3.158	Loss
CMGC_CDK_CDC2_CDK1_ST	P21333	FLNA	P06493	CDK1	S1084	P1085S	1085	Missense	proximal	1	no	3.355	0.171	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	3.158	Loss
CMGC_CDK_CDC2_CDK1_ST	P21333	FLNA	P06493	CDK1	S1084	D1091N	1091	Missense	distal	7	no	3.355	3.350	EPSD;PhosphoSitePlus	TCGA;ICGC	3.158	Down-regulation
CMGC_CDK_CDC2_CDK1_ST	P21333	FLNA	P06493	CDK1	S1084	L1077P	1077	Missense	distal	-7	no	3.355	3.516	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	3.158	Up-regulation
CMGC_CDK_CDC2_CDK1_ST	P21333	FLNA	P06493	CDK1	S1338	G1337V	1337	Missense	proximal	-1	no	3.349	3.275	EPSD	TCGA;ICGC;COSMIC	3.158	Down-regulation
CMGC_CDK_CDC2_CDK1_ST	P21333	FLNA	P06493	CDK1	S1338	F1345V	1345	Missense	distal	7	no	3.349	3.350	EPSD	TCGA;ICGC	3.158	Up-regulation
CMGC_CDK_CDC2_CDK1_ST	P21333	FLNA	P06493	CDK1	S2033	V2030M	2030	Missense	distal	-3	no	3.370	3.376	EPSD	TCGA;COSMIC	3.158	Up-regulation
CMGC_CDK_CDC2_CDK1_ST	P21333	FLNA	P06493	CDK1	S2033	P2036L	2036	Missense	distal	3	no	3.370	3.238	EPSD	TCGA;COSMIC	3.158	Down-regulation
CMGC_CDK_CDC2_CDK1_ST	P21333	FLNA	P06493	CDK1	S2180	Q2177H	2177	Missense	distal	-3	no	3.165	3.153	EPSD	TCGA;COSMIC	3.158	Loss
CMGC_CDK_CDC2_CDK1_ST	P21333	FLNA	P06493	CDK1	S2224	V2230L	2230	Missense	distal	6	no	3.485	3.459	EPSD	TCGA;COSMIC	3.158	Down-regulation
CMGC_CDK_CDC2_CDK1_ST	P21333	FLNA	P06493	CDK1	S2224	V2230M	2230	Missense	distal	6	no	3.485	3.500	EPSD	TCGA;COSMIC;GDSC;CCLE	3.158	Up-regulation
CMGC_CDK_CDC2_CDK1_ST	P21333	FLNA	P06493	CDK1	T2488	A2491S	2491	Missense	distal	3	no	3.302	3.249	EPSD	TCGA;COSMIC	3.158	Down-regulation
CMGC_CDK_CDC2_CDK1_ST	P21333	FLNA	P06493	CDK1	T2488	V2485A	2485	Missense	distal	-3	no	3.302	3.364	EPSD	TCGA;COSMIC	3.158	Up-regulation
CMGC_CDK_CDC2_CDK1_ST	P21333	FLNA	P06493	CDK1	T2488	R2484H	2484	Missense	distal	-4	no	3.302	3.298	EPSD	TCGA	3.158	Down-regulation
CMGC_CDK_CDC2_CDK1_ST	P21333	FLNA	P06493	CDK1	S2510	A2514V	2514	Missense	distal	4	no	4.141	4.006	EPSD	TCGA	3.158	Down-regulation
CMGC_CDK_CDC2_CDK1_ST	P21333	FLNA	P06493	CDK1	S2640	D2634N	2634	Missense	distal	-6	no	3.246	3.245	EPSD	TCGA;COSMIC	3.158	Down-regulation
CMGC_CDK_CDC2_CDK1_ST	P21333	FLNA	P06493	CDK1	S2640	R2643H	2643	Missense	distal	3	no	3.246	3.154	EPSD	TCGA;COSMIC	3.158	Loss
CMGC_CDK_CDC2_CDK1_ST	P21333	FLNA	P06493	CDK1	S2640	E2635K	2635	Missense	distal	-5	no	3.246	3.277	EPSD	TCGA;COSMIC	3.158	Up-regulation
CMGC_CDK_CDC2_CDK1_ST	P21333	FLNA	P06493	CDK1	S2640	I2637N	2637	Missense	distal	-3	no	3.246	3.270	EPSD	TCGA;COSMIC	3.158	Up-regulation
CMGC_CDK_CDC2_CDK1_ST	P08047	SP1	P06493	CDK1	T739	G736S	736	Missense	distal	-3	no	3.132	3.186	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	3.158	Gain
CMGC_CDK_CDC2_CDK1_ST	P19338	NCL	P06493	CDK1	S67	K71N	71	Missense	distal	4	no	3.190	3.185	EPSD	TCGA;ICGC;COSMIC;GDSC;CCLE	3.158	Down-regulation
CMGC_CDK_CDC2_CDK1_ST	P19338	NCL	P06493	CDK1	T121	G123A	123	Missense	proximal	2	no	3.354	3.325	PhosphoSitePlus;EPSD	TCGA;ICGC;COSMIC	3.158	Down-regulation
CMGC_CDK_CDC2_CDK1_ST	Q14135	VGLL4	P06493	CDK1	S103	R100H	100	Missense	distal	-3	no	3.240	3.251	EPSD	TCGA;COSMIC	3.158	Up-regulation
CMGC_CDK_CDC2_CDK1_ST	O95139	NDUFB6	P06493	CDK1	S29	R31W	31	Missense	proximal	2	no	3.676	3.683	PhosphoSitePlus;EPSD	TCGA;ICGC;COSMIC	3.158	Up-regulation
CMGC_CDK_CDC2_CDK1_ST	O95139	NDUFB6	P06493	CDK1	S29	E27K	27	Missense	proximal	-2	no	3.676	3.705	PhosphoSitePlus;EPSD	TCGA;ICGC;COSMIC	3.158	Up-regulation
CMGC_CDK_CDC2_CDK1_ST	O95139	NDUFB6	P06493	CDK1	S29	V34M	34	Missense	distal	5	no	3.676	3.596	PhosphoSitePlus;EPSD	TCGA;ICGC;COSMIC	3.158	Down-regulation
CMGC_CDK_CDC2_CDK1_ST	O95139	NDUFB6	P06493	CDK1	S55	P56S	56	Missense	proximal	1	no	3.931	0.746	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	3.158	Loss
CMGC_CDK_CDC2_CDK1_ST	O95139	NDUFB6	P06493	CDK1	S55	S55F	55	Missense	central	0	yes	3.931	0.000	EPSD;PhosphoSitePlus	TCGA;ICGC	3.158	Loss
CMGC_CDK_CDC2_CDK1_ST	O95139	NDUFB6	P06493	CDK1	S55	R58M	58	Missense	distal	3	no	3.931	3.821	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	3.158	Down-regulation
CMGC_CDK_CDC2_CDK1_ST	Q9HCH0	NCKAP5L	P06493	CDK1	S177	A172T	172	Missense	distal	-5	no	3.263	3.285	EPSD	TCGA;ICGC;COSMIC	3.158	Up-regulation
CMGC_CDK_CDC2_CDK1_ST	Q9HCH0	NCKAP5L	P06493	CDK1	S473	L476R	476	Missense	distal	3	no	2.909	3.163	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	3.158	Gain
CMGC_CDK_CDC2_CDK1_ST	P18031	PTPN1	P06493	CDK1	S50	D53H	53	Missense	distal	3	no	3.524	3.572	EPSD	TCGA;COSMIC	3.158	Up-regulation
CMGC_CDK_CDC2_CDK1_ST	P18031	PTPN1	P06493	CDK1	S50	Y46H	46	Missense	distal	-4	no	3.524	3.553	EPSD	TCGA;ICGC;COSMIC	3.158	Up-regulation
CMGC_CDK_CDC2_CDK1_ST	P18031	PTPN1	P06493	CDK1	S50	D48Y	48	Missense	proximal	-2	no	3.524	3.556	EPSD	TCGA;ICGC;COSMIC	3.158	Up-regulation
CMGC_CDK_CDC2_CDK1_ST	P18031	PTPN1	P06493	CDK1	S50	P51L	51	Missense	proximal	1	no	3.524	-0.162	EPSD	TCGA;ICGC	3.158	Loss
CMGC_CDK_CDC2_CDK1_ST	P18031	PTPN1	P06493	CDK1	S50	R43Q	43	Missense	distal	-7	no	3.524	3.531	EPSD	TCGA;ICGC	3.158	Up-regulation
CMGC_CDK_CDC2_CDK1_ST	P18031	PTPN1	P06493	CDK1	S386	S386F	386	Missense	central	0	yes	3.252	0.000	PhosphoSitePlus	TCGA;COSMIC	3.158	Loss
CMGC_CDK_CDC2_CDK1_ST	Q96R06	SPAG5	P06493	CDK1	S12	G18R	18	Missense	distal	6	no	3.675	3.734	EPSD	TCGA;ICGC;COSMIC	3.158	Up-regulation
CMGC_CDK_CDC2_CDK1_ST	Q96R06	SPAG5	P06493	CDK1	S12	K6Q	6	Missense	distal	-6	no	3.675	3.669	EPSD	TCGA;ICGC;COSMIC	3.158	Down-regulation
CMGC_CDK_CDC2_CDK1_ST	Q96R06	SPAG5	P06493	CDK1	S66	N63S	63	Missense	distal	-3	no	3.316	3.333	EPSD	TCGA;COSMIC	3.158	Up-regulation
CMGC_CDK_CDC2_CDK1_ST	Q96R06	SPAG5	P06493	CDK1	T111	S110C	110	Missense	proximal	-1	no	3.377	3.494	EPSD	TCGA;ICGC;COSMIC	3.158	Up-regulation
CMGC_CDK_CDC2_CDK1_ST	Q96R06	SPAG5	P06493	CDK1	T111	P106L	106	Missense	distal	-5	no	3.377	3.498	EPSD	TCGA;ICGC;COSMIC	3.158	Up-regulation
CMGC_CDK_CDC2_CDK1_ST	Q96R06	SPAG5	P06493	CDK1	S249	A253V	253	Missense	distal	4	no	3.678	3.542	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	3.158	Down-regulation
CMGC_CDK_CDC2_CDK1_ST	Q96R06	SPAG5	P06493	CDK1	S341	K348N	348	Missense	distal	7	no	3.275	3.273	EPSD	TCGA;ICGC;COSMIC	3.158	Down-regulation
CMGC_CDK_CDC2_CDK1_ST	Q96R06	SPAG5	P06493	CDK1	T963	P964Q	964	Missense	proximal	1	no	3.210	0.788	EPSD	TCGA;ICGC;COSMIC	3.158	Loss
CMGC_CDK_CDC2_CDK1_ST	Q9NTI5	PDS5B	P06493	CDK1	T1220	E1224G	1224	Missense	distal	4	no	3.222	3.158	EPSD	TCGA;ICGC;COSMIC	3.158	Down-regulation
CMGC_CDK_CDC2_CDK1_ST	Q9NTI5	PDS5B	P06493	CDK1	T1220	G1216C	1216	Missense	distal	-4	no	3.222	3.224	EPSD	TCGA;ICGC;COSMIC	3.158	Up-regulation
CMGC_CDK_CDC2_CDK1_ST	Q9NTI5	PDS5B	P06493	CDK1	T1220	V1222I	1222	Missense	proximal	2	no	3.222	3.227	EPSD	TCGA;ICGC;COSMIC	3.158	Up-regulation
CMGC_CDK_CDC2_CDK1_ST	Q9NTI5	PDS5B	P06493	CDK1	S1283	P1284L	1284	Missense	proximal	1	no	3.284	-0.402	EPSD	TCGA;ICGC;COSMIC;GDSC;CCLE	3.158	Loss
CMGC_CDK_CDC2_CDK1_ST	Q14CB8	ARHGAP19	P06493	CDK1	S470	S468C	468	Missense	proximal	-2	no	3.384	3.401	EPSD	TCGA;ICGC;COSMIC	3.158	Up-regulation
CMGC_CDK_CDC2_CDK1_ST	Q9H8V3	ECT2	P06493	CDK1	S121	P122S	122	Missense	proximal	1	no	3.520	0.335	EPSD	TCGA;COSMIC	3.158	Loss
CMGC_CDK_CDC2_CDK1_ST	Q9H8V3	ECT2	P06493	CDK1	S121	P122L	122	Missense	proximal	1	no	3.520	-0.166	EPSD	TCGA;COSMIC;CCLE	3.158	Loss
CMGC_CDK_CDC2_CDK1_ST	Q9H8V3	ECT2	P06493	CDK1	T422	S420A	420	Missense	proximal	-2	no	3.195	3.076	EPSD	TCGA;COSMIC	3.158	Loss
CMGC_CDK_CDC2_CDK1_ST	Q9H8V3	ECT2	P06493	CDK1	T422	S420F	420	Missense	proximal	-2	no	3.195	3.263	EPSD	TCGA;COSMIC	3.158	Up-regulation
CMGC_CDK_CDC2_CDK1_ST	Q9H8V3	ECT2	P06493	CDK1	T444	T444I	444	Missense	central	0	yes	3.438	0.000	EPSD;PhosphoSitePlus	TCGA;COSMIC	3.158	Loss
CMGC_CDK_CDC2_CDK1_ST	Q14978	NOLC1	P06493	CDK1	T259	R262Q	262	Missense	distal	3	no	3.207	3.158	EPSD	TCGA;COSMIC	3.158	Down-regulation
CMGC_CDK_CDC2_CDK1_ST	Q14978	NOLC1	P06493	CDK1	T259	K263N	263	Missense	distal	4	no	3.207	3.202	EPSD	TCGA	3.158	Down-regulation
CMGC_CDK_CDC2_CDK1_ST	Q13586	STIM1	P06493	CDK1	S486	S492P	492	Missense	distal	6	no	3.259	3.252	EPSD	TCGA;COSMIC	3.158	Down-regulation
CMGC_CDK_CDC2_CDK1_ST	Q13586	STIM1	P06493	CDK1	S600	A593T	593	Missense	distal	-7	no	3.181	3.174	EPSD	TCGA;COSMIC	3.158	Down-regulation
CMGC_CDK_CDC2_CDK1_ST	P11171	EPB41	P06493	CDK1	T378	D383H	383	Missense	distal	5	no	3.239	3.206	EPSD	TCGA;ICGC;COSMIC	3.158	Down-regulation
CMGC_CDK_CDC2_CDK1_ST	P11171	EPB41	P06493	CDK1	T378	H371R	371	Missense	distal	-7	no	3.239	3.264	EPSD	TCGA;ICGC;COSMIC	3.158	Up-regulation
CMGC_CDK_CDC2_CDK1_ST	P11171	EPB41	P06493	CDK1	S712	R707C	707	Missense	distal	-5	no	3.336	3.369	EPSD	TCGA;COSMIC	3.158	Up-regulation
CMGC_CDK_CDC2_CDK1_ST	P11171	EPB41	P06493	CDK1	S712	R707H	707	Missense	distal	-5	no	3.336	3.331	EPSD	TCGA;COSMIC;CCLE	3.158	Down-regulation
CMGC_CDK_CDC2_CDK1_ST	P11171	EPB41	P06493	CDK1	S712	R715Q	715	Missense	distal	3	no	3.336	3.287	EPSD	TCGA;COSMIC	3.158	Down-regulation
CMGC_CDK_CDC2_CDK1_ST	Q92974	ARHGEF2	P06493	CDK1	S648	R650C	650	Missense	proximal	2	no	3.293	3.300	EPSD	TCGA;COSMIC;CCLE	3.158	Up-regulation
CMGC_CDK_CDC2_CDK1_ST	Q92974	ARHGEF2	P06493	CDK1	S648	R653Q	653	Missense	distal	5	no	3.293	3.317	EPSD	TCGA;COSMIC	3.158	Up-regulation
CMGC_CDK_CDC2_CDK1_ST	Q92974	ARHGEF2	P06493	CDK1	T679	V674M	674	Missense	distal	-5	no	3.161	3.099	EPSD	TCGA	3.158	Loss
CMGC_CDK_CDC2_CDK1_ST	Q92974	ARHGEF2	P06493	CDK1	S733	A738V	738	Missense	distal	5	no	3.089	3.296	EPSD	TCGA;COSMIC	3.158	Gain
CMGC_CDK_CDC2_CDK1_ST	Q92974	ARHGEF2	P06493	CDK1	S932	R936W	936	Missense	distal	4	no	3.444	3.371	EPSD	TCGA;COSMIC	3.158	Down-regulation
CMGC_CDK_CDC2_CDK1_ST	Q92974	ARHGEF2	P06493	CDK1	S932	P933L	933	Missense	proximal	1	no	3.444	-0.243	EPSD	TCGA;COSMIC	3.158	Loss
CMGC_CDK_CDC2_CDK1_ST	Q92974	ARHGEF2	P06493	CDK1	S956	S953R	953	Missense	distal	-3	no	3.517	3.490	EPSD	TCGA;COSMIC	3.158	Down-regulation
CMGC_CDK_CDC2_CDK1_ST	Q92974	ARHGEF2	P06493	CDK1	S956	R954H	954	Missense	proximal	-2	no	3.517	3.471	EPSD	TCGA;COSMIC	3.158	Down-regulation
CMGC_CDK_CDC2_CDK1_ST	Q92974	ARHGEF2	P06493	CDK1	S956	R954C	954	Missense	proximal	-2	no	3.517	3.467	EPSD	TCGA;COSMIC	3.158	Down-regulation
CMGC_CDK_CDC2_CDK1_ST	Q92974	ARHGEF2	P06493	CDK1	S956	S960N	960	Missense	distal	4	no	3.517	3.499	EPSD	TCGA;COSMIC	3.158	Down-regulation
CMGC_CDK_CDC2_CDK1_ST	Q14202	ZMYM3	P06493	CDK1	S8	D5Y	5	Missense	distal	-3	no	3.266	3.251	EPSD	TCGA;ICGC;COSMIC	3.158	Down-regulation
CMGC_CDK_CDC2_CDK1_ST	Q14202	ZMYM3	P06493	CDK1	S51	S54L	54	Missense	distal	3	no	3.634	3.451	EPSD	TCGA;ICGC;COSMIC	3.158	Down-regulation
CMGC_CDK_CDC2_CDK1_ST	Q14202	ZMYM3	P06493	CDK1	T62	D69N	69	Missense	distal	7	no	3.497	3.491	EPSD	TCGA	3.158	Down-regulation
CMGC_CDK_CDC2_CDK1_ST	Q14202	ZMYM3	P06493	CDK1	S91	P92L	92	Missense	proximal	1	no	3.201	-0.486	EPSD	TCGA;ICGC;COSMIC	3.158	Loss
CMGC_CDK_CDC2_CDK1_ST	Q14202	ZMYM3	P06493	CDK1	S91	Y87S	87	Missense	distal	-4	no	3.201	3.300	EPSD	TCGA;ICGC;COSMIC	3.158	Up-regulation
CMGC_CDK_CDC2_CDK1_ST	Q14202	ZMYM3	P06493	CDK1	S91	P93A	93	Missense	proximal	2	no	3.201	3.193	EPSD	TCGA;ICGC;COSMIC	3.158	Down-regulation
CMGC_CDK_CDC2_CDK1_ST	Q14202	ZMYM3	P06493	CDK1	S91	E94D	94	Missense	distal	3	no	3.201	3.183	EPSD	TCGA;ICGC	3.158	Down-regulation
CMGC_CDK_CDC2_CDK1_ST	Q14202	ZMYM3	P06493	CDK1	S154	E159K	159	Missense	distal	5	no	3.181	3.133	EPSD	TCGA;ICGC;COSMIC	3.158	Loss
CMGC_CDK_CDC2_CDK1_ST	Q14202	ZMYM3	P06493	CDK1	S154	E161K	161	Missense	distal	7	no	3.181	3.177	EPSD	TCGA;ICGC;COSMIC	3.158	Down-regulation
CMGC_CDK_CDC2_CDK1_ST	Q14202	ZMYM3	P06493	CDK1	S154	S148Y	148	Missense	distal	-6	no	3.181	3.199	EPSD	TCGA;ICGC;COSMIC	3.158	Up-regulation
CMGC_CDK_CDC2_CDK1_ST	Q14202	ZMYM3	P06493	CDK1	S154	E160D	160	Missense	distal	6	no	3.181	3.179	EPSD	TCGA;ICGC;COSMIC	3.158	Down-regulation
CMGC_CDK_CDC2_CDK1_ST	Q14202	ZMYM3	P06493	CDK1	S287	R293C	293	Missense	distal	6	no	3.232	3.195	EPSD	TCGA;ICGC;COSMIC	3.158	Down-regulation
CMGC_CDK_CDC2_CDK1_ST	Q14202	ZMYM3	P06493	CDK1	S287	P284H	284	Missense	distal	-3	no	3.232	3.216	EPSD	TCGA;ICGC;COSMIC	3.158	Down-regulation
CMGC_CDK_CDC2_CDK1_ST	Q14202	ZMYM3	P06493	CDK1	S287	R293H	293	Missense	distal	6	no	3.232	3.214	EPSD	TCGA;ICGC;COSMIC	3.158	Down-regulation
CMGC_CDK_CDC2_CDK1_ST	Q14202	ZMYM3	P06493	CDK1	S464	G466V	466	Missense	proximal	2	no	3.456	3.449	EPSD	TCGA;ICGC;COSMIC	3.158	Down-regulation
CMGC_CDK_CDC2_CDK1_ST	Q14202	ZMYM3	P06493	CDK1	S464	L470P	470	Missense	distal	6	no	3.456	3.512	EPSD	TCGA;ICGC;COSMIC	3.158	Up-regulation
CMGC_CDK_CDC2_CDK1_ST	Q14202	ZMYM3	P06493	CDK1	S464	T462I	462	Missense	proximal	-2	no	3.456	3.589	EPSD	TCGA;ICGC;COSMIC	3.158	Up-regulation
CMGC_CDK_CDC2_CDK1_ST	Q14202	ZMYM3	P06493	CDK1	S464	E468A	468	Missense	distal	4	no	3.456	3.560	EPSD	TCGA;ICGC;COSMIC	3.158	Up-regulation
CMGC_CDK_CDC2_CDK1_ST	Q14202	ZMYM3	P06493	CDK1	S464	F471L	471	Missense	distal	7	no	3.456	3.464	EPSD	TCGA;ICGC	3.158	Up-regulation
CMGC_CDK_CDC2_CDK1_ST	Q14202	ZMYM3	P06493	CDK1	S582	G586V	586	Missense	distal	4	no	3.152	3.184	EPSD	TCGA;COSMIC	3.158	Gain
CMGC_CDK_CDC2_CDK1_ST	Q14202	ZMYM3	P06493	CDK1	S582	G586D	586	Missense	distal	4	no	3.152	3.215	EPSD	TCGA	3.158	Gain
CMGC_CDK_CDC2_CDK1_ST	Q14202	ZMYM3	P06493	CDK1	S774	S774F	774	Missense	central	0	yes	3.322	0.000	EPSD	TCGA;COSMIC	3.158	Loss
CMGC_CDK_CDC2_CDK1_ST	Q14202	ZMYM3	P06493	CDK1	S774	P779S	779	Missense	distal	5	no	3.322	3.293	EPSD	TCGA	3.158	Down-regulation
CMGC_CDK_CDC2_CDK1_ST	Q9UQ35	SRRM2	P06493	CDK1	T111	G107A	107	Missense	distal	-4	no	3.260	3.370	EPSD	TCGA;ICGC;COSMIC	3.158	Up-regulation
CMGC_CDK_CDC2_CDK1_ST	Q9UQ35	SRRM2	P06493	CDK1	T111	Q114H	114	Missense	distal	3	no	3.260	3.216	EPSD	TCGA;ICGC;COSMIC;GDSC;CCLE	3.158	Down-regulation
CMGC_CDK_CDC2_CDK1_ST	Q9UQ35	SRRM2	P06493	CDK1	S353	S358N	358	Missense	distal	5	no	3.215	3.256	EPSD	TCGA;ICGC;COSMIC	3.158	Up-regulation
CMGC_CDK_CDC2_CDK1_ST	Q9UQ35	SRRM2	P06493	CDK1	T651	R650K	650	Missense	proximal	-1	no	3.117	3.186	EPSD	TCGA;ICGC;COSMIC	3.158	Gain
CMGC_CDK_CDC2_CDK1_ST	Q9UQ35	SRRM2	P06493	CDK1	T983	P981S	981	Missense	proximal	-2	no	3.215	3.341	EPSD	TCGA;ICGC;COSMIC	3.158	Up-regulation
CMGC_CDK_CDC2_CDK1_ST	Q9UQ35	SRRM2	P06493	CDK1	T983	H989Y	989	Missense	distal	6	no	3.215	3.189	EPSD	TCGA;ICGC;COSMIC;GDSC;CCLE	3.158	Down-regulation
CMGC_CDK_CDC2_CDK1_ST	Q9UQ35	SRRM2	P06493	CDK1	S994	G991V	991	Missense	distal	-3	no	3.309	3.343	EPSD	TCGA;ICGC;COSMIC	3.158	Up-regulation
CMGC_CDK_CDC2_CDK1_ST	Q9UQ35	SRRM2	P06493	CDK1	S994	H989Y	989	Missense	distal	-5	no	3.309	3.337	EPSD	TCGA;ICGC;COSMIC;GDSC;CCLE	3.158	Up-regulation
CMGC_CDK_CDC2_CDK1_ST	Q9UQ35	SRRM2	P06493	CDK1	S994	G991E	991	Missense	distal	-3	no	3.309	3.336	EPSD	TCGA;ICGC	3.158	Up-regulation
CMGC_CDK_CDC2_CDK1_ST	Q9UQ35	SRRM2	P06493	CDK1	S1179	A1178V	1178	Missense	proximal	-1	no	2.974	3.174	EPSD	TCGA;ICGC;COSMIC	3.158	Gain
CMGC_CDK_CDC2_CDK1_ST	Q9UQ35	SRRM2	P06493	CDK1	S1713	R1719I	1719	Missense	distal	6	no	3.161	3.105	EPSD	TCGA;ICGC;COSMIC	3.158	Loss
CMGC_CDK_CDC2_CDK1_ST	Q9UQ35	SRRM2	P06493	CDK1	S1713	R1717H	1717	Missense	distal	4	no	3.161	3.119	EPSD	TCGA;ICGC;COSMIC	3.158	Loss
CMGC_CDK_CDC2_CDK1_ST	Q9UQ35	SRRM2	P06493	CDK1	S1713	S1718C	1718	Missense	distal	5	no	3.161	3.259	EPSD	TCGA;ICGC;COSMIC	3.158	Up-regulation
CMGC_CDK_CDC2_CDK1_ST	Q9UQ35	SRRM2	P06493	CDK1	S1713	R1708C	1708	Missense	distal	-5	no	3.161	3.194	EPSD	TCGA;ICGC;COSMIC	3.158	Up-regulation
CMGC_CDK_CDC2_CDK1_ST	Q9UQ35	SRRM2	P06493	CDK1	S2123	R2119H	2119	Missense	distal	-4	no	3.432	3.428	EPSD	TCGA;ICGC;COSMIC	3.158	Down-regulation
CMGC_CDK_CDC2_CDK1_ST	Q9UQ35	SRRM2	P06493	CDK1	S2123	R2129C	2129	Missense	distal	6	no	3.432	3.394	EPSD	TCGA;ICGC;COSMIC;GDSC	3.158	Down-regulation
CMGC_CDK_CDC2_CDK1_ST	Q9UQ35	SRRM2	P06493	CDK1	S2123	R2119C	2119	Missense	distal	-4	no	3.432	3.362	EPSD	TCGA;ICGC;COSMIC	3.158	Down-regulation
CMGC_CDK_CDC2_CDK1_ST	Q9UQ35	SRRM2	P06493	CDK1	S2123	P2126L	2126	Missense	distal	3	no	3.432	3.299	EPSD	TCGA;ICGC	3.158	Down-regulation
CMGC_CDK_CDC2_CDK1_ST	Q9UQ35	SRRM2	P06493	CDK1	T2125	R2119H	2119	Missense	distal	-6	no	3.266	3.270	EPSD	TCGA;ICGC;COSMIC	3.158	Up-regulation
CMGC_CDK_CDC2_CDK1_ST	Q9UQ35	SRRM2	P06493	CDK1	T2125	R2129C	2129	Missense	distal	4	no	3.266	3.201	EPSD	TCGA;ICGC;COSMIC;GDSC	3.158	Down-regulation
CMGC_CDK_CDC2_CDK1_ST	Q9UQ35	SRRM2	P06493	CDK1	T2125	R2119C	2119	Missense	distal	-6	no	3.266	3.275	EPSD	TCGA;ICGC;COSMIC	3.158	Up-regulation
CMGC_CDK_CDC2_CDK1_ST	Q9UQ35	SRRM2	P06493	CDK1	T2125	P2126L	2126	Missense	proximal	1	no	3.266	-0.421	EPSD	TCGA;ICGC	3.158	Loss
CMGC_CDK_CDC2_CDK1_ST	Q9UQ35	SRRM2	P06493	CDK1	S2132	R2129C	2129	Missense	distal	-3	no	3.271	3.282	EPSD	TCGA;ICGC;COSMIC;GDSC	3.158	Up-regulation
CMGC_CDK_CDC2_CDK1_ST	Q9UQ35	SRRM2	P06493	CDK1	S2132	P2126L	2126	Missense	distal	-6	no	3.271	3.298	EPSD	TCGA;ICGC	3.158	Up-regulation
CMGC_CDK_CDC2_CDK1_ST	Q9UQ35	SRRM2	P06493	CDK1	S2650	S2645L	2645	Missense	distal	-5	no	3.133	3.276	EPSD	TCGA;ICGC	3.158	Gain
CMGC_CDK_CDC2_CDK1_ST	P30260	CDC27	P06493	CDK1	T68	Y73H	73	Missense	distal	5	no	3.903	3.841	EPSD	TCGA;ICGC;COSMIC	3.158	Down-regulation
CMGC_CDK_CDC2_CDK1_ST	P30260	CDC27	P06493	CDK1	T68	K62E	62	Missense	distal	-6	no	3.903	3.902	EPSD	TCGA;ICGC;COSMIC	3.158	Down-regulation
CMGC_CDK_CDC2_CDK1_ST	P17302	GJA1	P06493	CDK1	S279	A276T	276	Missense	distal	-3	no	3.531	3.494	EPSD	TCGA;ICGC;COSMIC	3.158	Down-regulation
CMGC_CDK_CDC2_CDK1_ST	P17302	GJA1	P06493	CDK1	S279	T275I	275	Missense	distal	-4	no	3.531	3.379	EPSD	TCGA;ICGC;COSMIC	3.158	Down-regulation
CMGC_CDK_CDC2_CDK1_ST	P46937	YAP1	P06493	CDK1	T143	S138F	138	Missense	distal	-5	no	3.701	3.811	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	3.158	Up-regulation
CMGC_CDK_CDC2_CDK1_ST	P46937	YAP1	P06493	CDK1	T143	G140E	140	Missense	distal	-3	no	3.701	3.729	EPSD;PhosphoSitePlus	TCGA;ICGC	3.158	Up-regulation
CMGC_CDK_CDC2_CDK1_ST	P38936	CDKN1A	P06493	CDK1	T57	G61V	61	Missense	distal	4	no	3.807	3.839	EPSD	TCGA;ICGC;COSMIC	3.158	Up-regulation
CMGC_CDK_CDC2_CDK1_ST	P38936	CDKN1A	P06493	CDK1	T57	E56K	56	Missense	proximal	-1	no	3.807	3.846	EPSD	TCGA;ICGC;COSMIC	3.158	Up-regulation
CMGC_CDK_CDC2_CDK1_ST	P38936	CDKN1A	P06493	CDK1	T57	P58L	58	Missense	proximal	1	no	3.807	0.121	EPSD	TCGA;ICGC;COSMIC	3.158	Loss
CMGC_CDK_CDC2_CDK1_ST	P38936	CDKN1A	P06493	CDK1	S98	R94W	94	Missense	distal	-4	no	3.213	3.173	EPSD	TCGA;ICGC;COSMIC	3.158	Down-regulation
CMGC_CDK_CDC2_CDK1_ST	P38936	CDKN1A	P06493	CDK1	S98	R93S	93	Missense	distal	-5	no	3.213	3.156	EPSD	TCGA;ICGC;COSMIC	3.158	Loss
CMGC_CDK_CDC2_CDK1_ST	P38936	CDKN1A	P06493	CDK1	S98	R94P	94	Missense	distal	-4	no	3.213	3.229	EPSD	TCGA;ICGC;COSMIC	3.158	Up-regulation
CMGC_CDK_CDC2_CDK1_ST	Q32P44	EML3	P06493	CDK1	S198	G200V	200	Missense	proximal	2	no	3.331	3.324	EPSD	TCGA;COSMIC	3.158	Down-regulation
CMGC_CDK_CDC2_CDK1_ST	Q32P44	EML3	P06493	CDK1	S198	P202S	202	Missense	distal	4	no	3.331	3.327	EPSD	TCGA;ICGC;COSMIC	3.158	Down-regulation
CMGC_CDK_CDC2_CDK1_ST	Q32P44	EML3	P06493	CDK1	S198	R205L	205	Missense	distal	7	no	3.331	3.353	EPSD	TCGA;COSMIC	3.158	Up-regulation
CMGC_CDK_CDC2_CDK1_ST	Q32P44	EML3	P06493	CDK1	T494	R487W	487	Missense	distal	-7	no	3.545	3.475	EPSD	TCGA;COSMIC;GDSC;CCLE	3.158	Down-regulation
CMGC_CDK_CDC2_CDK1_ST	Q32P44	EML3	P06493	CDK1	T494	A500T	500	Missense	distal	6	no	3.545	3.537	EPSD	TCGA;COSMIC	3.158	Down-regulation
CMGC_CDK_CDC2_CDK1_ST	Q32P44	EML3	P06493	CDK1	T494	G496C	496	Missense	proximal	2	no	3.545	3.536	EPSD	TCGA	3.158	Down-regulation
CMGC_CDK_CDC2_CDK1_ST	Q32P44	EML3	P06493	CDK1	S689	A696P	696	Missense	distal	7	no	3.210	3.223	EPSD	TCGA;COSMIC	3.158	Up-regulation
CMGC_CDK_CDC2_CDK1_ST	Q9H1A4	ANAPC1	P06493	CDK1	T221	E219K	219	Missense	proximal	-2	no	3.178	3.206	EPSD	TCGA;ICGC;COSMIC	3.158	Up-regulation
CMGC_CDK_CDC2_CDK1_ST	Q9H1A4	ANAPC1	P06493	CDK1	T291	S286Y	286	Missense	distal	-5	no	3.507	3.588	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	3.158	Up-regulation
CMGC_CDK_CDC2_CDK1_ST	Q9H1A4	ANAPC1	P06493	CDK1	S377	R380I	380	Missense	distal	3	no	3.324	3.157	EPSD;PhosphoSitePlus	TCGA;ICGC	3.158	Loss
CMGC_CDK_CDC2_CDK1_ST	Q9H1A4	ANAPC1	P06493	CDK1	S377	N370S	370	Missense	distal	-7	no	3.324	3.384	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	3.158	Up-regulation
CMGC_CDK_CDC2_CDK1_ST	Q9H1A4	ANAPC1	P06493	CDK1	T537	P538A	538	Missense	proximal	1	no	3.205	2.316	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	3.158	Loss
CMGC_CDK_CDC2_CDK1_ST	Q9H1A4	ANAPC1	P06493	CDK1	T537	D533H	533	Missense	distal	-4	no	3.205	3.193	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	3.158	Down-regulation
CMGC_CDK_CDC2_CDK1_ST	Q9H1A4	ANAPC1	P06493	CDK1	S555	P558L	558	Missense	distal	3	no	3.424	3.291	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	3.158	Down-regulation
CMGC_CDK_CDC2_CDK1_ST	Q9H1A4	ANAPC1	P06493	CDK1	S731	S736L	736	Missense	distal	5	no	3.120	3.333	EPSD	TCGA;ICGC	3.158	Gain
CMGC_CDK_CDC2_CDK1_ST	Q9H1A4	ANAPC1	P06493	CDK1	S731	R726I	726	Missense	distal	-5	no	3.120	3.192	EPSD	TCGA;ICGC	3.158	Gain
CMGC_CDK_CDC2_CDK1_ST	P23443	RPS6KB1	P06493	CDK1	T390	Q389E	389	Missense	proximal	-1	no	3.171	3.214	EPSD	TCGA;COSMIC	3.158	Up-regulation
CMGC_CDK_CDC2_CDK1_ST	Q8IZD2	KMT2E	P06493	CDK1	T904	D902N	902	Missense	proximal	-2	no	3.351	3.362	EPSD	TCGA;ICGC;COSMIC	3.158	Up-regulation
CMGC_CDK_CDC2_CDK1_ST	Q8IZD2	KMT2E	P06493	CDK1	T904	T901A	901	Missense	distal	-3	no	3.351	3.388	EPSD	TCGA;ICGC;COSMIC	3.158	Up-regulation
CMGC_CDK_CDC2_CDK1_ST	Q8IZD2	KMT2E	P06493	CDK1	T904	S909C	909	Missense	distal	5	no	3.351	3.449	EPSD	TCGA;ICGC;COSMIC	3.158	Up-regulation
CMGC_CDK_CDC2_CDK1_ST	Q8IZD2	KMT2E	P06493	CDK1	T904	S909F	909	Missense	distal	5	no	3.351	3.518	EPSD	TCGA;ICGC;COSMIC	3.158	Up-regulation
CMGC_CDK_CDC2_CDK1_ST	Q8IZD2	KMT2E	P06493	CDK1	T1088	T1088I	1088	Missense	central	0	yes	3.506	0.000	EPSD	TCGA;ICGC;COSMIC	3.158	Loss
CMGC_CDK_CDC2_CDK1_ST	Q8IZD2	KMT2E	P06493	CDK1	T1088	D1086V	1086	Missense	proximal	-2	no	3.506	3.533	EPSD	TCGA;ICGC;COSMIC	3.158	Up-regulation
CMGC_CDK_CDC2_CDK1_ST	Q8IZD2	KMT2E	P06493	CDK1	T1088	R1085K	1085	Missense	distal	-3	no	3.506	3.495	EPSD	TCGA;ICGC;COSMIC	3.158	Down-regulation
CMGC_CDK_CDC2_CDK1_ST	Q8IZD2	KMT2E	P06493	CDK1	T1147	K1154N	1154	Missense	distal	7	no	3.525	3.523	EPSD	TCGA;ICGC;COSMIC	3.158	Down-regulation
CMGC_CDK_CDC2_CDK1_ST	Q8IZD2	KMT2E	P06493	CDK1	T1147	D1143N	1143	Missense	distal	-4	no	3.525	3.511	EPSD	TCGA;ICGC;COSMIC	3.158	Down-regulation
CMGC_CDK_CDC2_CDK1_ST	Q8IZD2	KMT2E	P06493	CDK1	S1285	D1278H	1278	Missense	distal	-7	no	3.260	3.259	EPSD	TCGA;ICGC;COSMIC	3.158	Down-regulation
CMGC_CDK_CDC2_CDK1_ST	Q8IZD2	KMT2E	P06493	CDK1	S1466	P1470S	1470	Missense	distal	4	no	3.210	3.206	EPSD	TCGA;COSMIC	3.158	Down-regulation
CMGC_CDK_CDC2_CDK1_ST	Q8IZD2	KMT2E	P06493	CDK1	S1466	P1467T	1467	Missense	proximal	1	no	3.210	0.777	EPSD	TCGA;COSMIC	3.158	Loss
CMGC_CDK_CDC2_CDK1_ST	P12270	TPR	P06493	CDK1	T653	S648L	648	Missense	distal	-5	no	3.119	3.263	EPSD	TCGA;ICGC;COSMIC	3.158	Gain
CMGC_CDK_CDC2_CDK1_ST	P12270	TPR	P06493	CDK1	T2137	P2135L	2135	Missense	proximal	-2	no	3.101	3.274	EPSD	TCGA;ICGC;COSMIC	3.158	Gain
CMGC_CDK_CDC2_CDK1_ST	P12270	TPR	P06493	CDK1	T2137	E2130A	2130	Missense	distal	-7	no	3.101	3.195	EPSD	TCGA;ICGC;COSMIC	3.158	Gain
CMGC_CDK_CDC2_CDK1_ST	Q7Z3J3	RGPD4	P06493	CDK1	T1153	L1156V	1156	Missense	distal	3	no	3.371	3.454	EPSD	TCGA;ICGC;COSMIC	3.158	Up-regulation
CMGC_CDK_CDC2_CDK1_ST	Q7Z3J3	RGPD4	P06493	CDK1	T1153	F1160L	1160	Missense	distal	7	no	3.371	3.379	EPSD	TCGA;ICGC;COSMIC	3.158	Up-regulation
CMGC_CDK_CDC2_CDK1_ST	Q7Z3J3	RGPD4	P06493	CDK1	T1153	F1160C	1160	Missense	distal	7	no	3.371	3.363	EPSD	TCGA;ICGC;COSMIC	3.158	Down-regulation
CMGC_CDK_CDC2_CDK1_ST	Q7Z3J3	RGPD4	P06493	CDK1	T1153	R1146W	1146	Missense	distal	-7	no	3.371	3.301	EPSD	TCGA;ICGC;COSMIC	3.158	Down-regulation
CMGC_CDK_CDC2_CDK1_ST	Q7Z3J3	RGPD4	P06493	CDK1	T1178	L1182P	1182	Missense	distal	4	no	3.040	3.162	EPSD	TCGA;ICGC;COSMIC	3.158	Gain
CMGC_CDK_CDC2_CDK1_ST	Q7Z3J3	RGPD4	P06493	CDK1	S1305	N1310H	1310	Missense	distal	5	no	3.498	3.513	EPSD	TCGA;ICGC;COSMIC	3.158	Up-regulation
CMGC_CDK_CDC2_CDK1_ST	Q7Z3J3	RGPD4	P06493	CDK1	T1412	L1405R	1405	Missense	distal	-7	no	3.095	3.259	EPSD	TCGA;ICGC;COSMIC	3.158	Gain
CMGC_CDK_CDC2_CDK1_ST	Q7Z3J3	RGPD4	P06493	CDK1	T1475	S1482N	1482	Missense	distal	7	no	3.386	3.394	EPSD	TCGA	3.158	Up-regulation
CMGC_CDK_CDC2_CDK1_ST	Q7Z3J3	RGPD4	P06493	CDK1	T1475	E1469K	1469	Missense	distal	-6	no	3.386	3.388	EPSD	TCGA;ICGC;COSMIC	3.158	Up-regulation
CMGC_CDK_CDC2_CDK1_ST	Q7Z3J3	RGPD4	P06493	CDK1	T1475	S1472Y	1472	Missense	distal	-3	no	3.386	3.354	EPSD	TCGA;ICGC;COSMIC	3.158	Down-regulation
CMGC_CDK_CDC2_CDK1_ST	Q7Z3J3	RGPD4	P06493	CDK1	S1487	S1482N	1482	Missense	distal	-5	no	3.270	3.318	EPSD	TCGA	3.158	Up-regulation
CMGC_CDK_CDC2_CDK1_ST	Q7Z3J3	RGPD4	P06493	CDK1	S1487	R1485T	1485	Missense	proximal	-2	no	3.270	3.164	EPSD	TCGA;ICGC;COSMIC	3.158	Down-regulation
CMGC_CDK_CDC2_CDK1_ST	Q7Z3J3	RGPD4	P06493	CDK1	T1638	K1641R	1641	Missense	distal	3	no	3.440	3.457	EPSD	TCGA;ICGC;COSMIC	3.158	Up-regulation
CMGC_CDK_CDC2_CDK1_ST	Q9GZM8	NDEL1	P06493	CDK1	S242	S247F	247	Missense	distal	5	no	3.162	3.328	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	3.158	Up-regulation
CMGC_CDK_CDC2_CDK1_ST	Q9GZM8	NDEL1	P06493	CDK1	T245	S247F	247	Missense	proximal	2	no	3.397	3.419	PhosphoSitePlus;EPSD	TCGA;ICGC;COSMIC	3.158	Up-regulation
CMGC_CDK_CDC2_CDK1_ST	Q16659	MAPK6	P06493	CDK1	S688	H683D	683	Missense	distal	-5	no	3.314	3.305	PhosphoSitePlus;EPSD	TCGA;ICGC;COSMIC	3.158	Down-regulation
CMGC_CDK_CDC2_CDK1_ST	Q13428	TCOF1	P06493	CDK1	S233	P240S	240	Missense	distal	7	no	3.648	3.646	EPSD	TCGA;ICGC;COSMIC	3.158	Down-regulation
CMGC_CDK_CDC2_CDK1_ST	Q13428	TCOF1	P06493	CDK1	S233	P234A	234	Missense	proximal	1	no	3.648	2.759	EPSD	TCGA;ICGC;COSMIC	3.158	Loss
CMGC_CDK_CDC2_CDK1_ST	Q13428	TCOF1	P06493	CDK1	S823	Q821R	821	Missense	proximal	-2	no	3.188	3.242	EPSD	TCGA;ICGC;COSMIC	3.158	Up-regulation
CMGC_CDK_CDC2_CDK1_ST	Q13428	TCOF1	P06493	CDK1	S823	Q821H	821	Missense	proximal	-2	no	3.188	3.196	EPSD	TCGA;ICGC;COSMIC	3.158	Up-regulation
CMGC_CDK_CDC2_CDK1_ST	Q13428	TCOF1	P06493	CDK1	S823	S823F	823	Missense	central	0	yes	3.188	0.000	EPSD	TCGA;ICGC;COSMIC	3.158	Loss
CMGC_CDK_CDC2_CDK1_ST	Q13428	TCOF1	P06493	CDK1	T1270	S1274F	1274	Missense	distal	4	no	3.403	3.307	EPSD	TCGA;COSMIC	3.158	Down-regulation
CMGC_CDK_CDC2_CDK1_ST	Q13428	TCOF1	P06493	CDK1	S1378	S1383F	1383	Missense	distal	5	no	3.685	3.852	EPSD	TCGA;COSMIC	3.158	Up-regulation
CMGC_CDK_CDC2_CDK1_ST	Q01581	HMGCS1	P06493	CDK1	T471	P470R	470	Missense	proximal	-1	no	3.222	3.233	EPSD	TCGA;ICGC;COSMIC	3.158	Up-regulation
CMGC_CDK_CDC2_CDK1_ST	Q96GX5	MASTL	P06493	CDK1	T261	Y263F	263	Missense	proximal	2	no	3.352	3.358	EPSD	TCGA;ICGC;COSMIC	3.158	Up-regulation
CMGC_CDK_CDC2_CDK1_ST	Q96GX5	MASTL	P06493	CDK1	T261	T261A	261	Missense	central	0	yes	3.352	0.000	EPSD	TCGA;ICGC;COSMIC	3.158	Loss
CMGC_CDK_CDC2_CDK1_ST	Q96GX5	MASTL	P06493	CDK1	T380	T381P	381	Missense	proximal	1	no	1.376	3.809	EPSD	TCGA;ICGC;COSMIC	3.158	Gain
CMGC_CDK_CDC2_CDK1_ST	Q96GX5	MASTL	P06493	CDK1	S453	S452C	452	Missense	proximal	-1	no	3.169	3.286	EPSD	TCGA;ICGC;COSMIC	3.158	Up-regulation
CMGC_CDK_CDC2_CDK1_ST	Q96GX5	MASTL	P06493	CDK1	S453	K457N	457	Missense	distal	4	no	3.169	3.164	EPSD	TCGA;ICGC;COSMIC	3.158	Down-regulation
CMGC_CDK_CDC2_CDK1_ST	Q96GX5	MASTL	P06493	CDK1	T519	D515N	515	Missense	distal	-4	no	3.259	3.245	EPSD	TCGA;ICGC;COSMIC	3.158	Down-regulation
CMGC_CDK_CDC2_CDK1_ST	Q96GX5	MASTL	P06493	CDK1	T519	S512Y	512	Missense	distal	-7	no	3.259	3.144	EPSD	TCGA;ICGC;COSMIC	3.158	Loss
CMGC_CDK_CDC2_CDK1_ST	Q96GX5	MASTL	P06493	CDK1	T710	P706S	706	Missense	distal	-4	no	3.401	3.452	EPSD	TCGA;ICGC;COSMIC	3.158	Up-regulation
CMGC_CDK_CDC2_CDK1_ST	Q96GX5	MASTL	P06493	CDK1	T710	S716L	716	Missense	distal	6	no	3.401	3.337	EPSD	TCGA;COSMIC	3.158	Down-regulation
CMGC_CDK_CDC2_CDK1_ST	Q96GX5	MASTL	P06493	CDK1	T718	R721Q	721	Missense	distal	3	no	3.397	3.348	EPSD	TCGA;COSMIC;CCLE	3.158	Down-regulation
CMGC_CDK_CDC2_CDK1_ST	Q96GX5	MASTL	P06493	CDK1	T718	S716L	716	Missense	proximal	-2	no	3.397	3.444	EPSD	TCGA;COSMIC	3.158	Up-regulation
CMGC_CDK_CDC2_CDK1_ST	Q96GX5	MASTL	P06493	CDK1	T722	R721Q	721	Missense	proximal	-1	no	3.459	3.447	EPSD	TCGA;COSMIC;CCLE	3.158	Down-regulation
CMGC_CDK_CDC2_CDK1_ST	Q96GX5	MASTL	P06493	CDK1	T722	S716L	716	Missense	distal	-6	no	3.459	3.487	EPSD	TCGA;COSMIC	3.158	Up-regulation
CMGC_CDK_CDC2_CDK1_ST	Q14493	SLBP	P06493	CDK1	T238	D231N	231	Missense	distal	-7	no	3.325	3.326	EPSD	TCGA;COSMIC	3.158	Up-regulation
CMGC_CDK_CDC2_CDK1_ST	P50570	DNM2	P06493	CDK1	S116	I120M	120	Missense	distal	4	no	3.426	3.488	EPSD	TCGA;ICGC;COSMIC	3.158	Up-regulation
CMGC_CDK_CDC2_CDK1_ST	P50570	DNM2	P06493	CDK1	S116	G114S	114	Missense	proximal	-2	no	3.426	3.336	EPSD	TCGA;ICGC;COSMIC	3.158	Down-regulation
CMGC_CDK_CDC2_CDK1_ST	P50570	DNM2	P06493	CDK1	S116	I120T	120	Missense	distal	4	no	3.426	3.529	EPSD	TCGA;ICGC;COSMIC	3.158	Up-regulation
CMGC_CDK_CDC2_CDK1_ST	P50570	DNM2	P06493	CDK1	S126	V129M	129	Missense	distal	3	no	3.421	3.482	EPSD	TCGA;ICGC;COSMIC	3.158	Up-regulation
CMGC_CDK_CDC2_CDK1_ST	P50570	DNM2	P06493	CDK1	S126	I120M	120	Missense	distal	-6	no	3.421	3.409	EPSD	TCGA;ICGC;COSMIC	3.158	Down-regulation
CMGC_CDK_CDC2_CDK1_ST	P50570	DNM2	P06493	CDK1	S126	I120T	120	Missense	distal	-6	no	3.421	3.397	EPSD	TCGA;ICGC;COSMIC	3.158	Down-regulation
CMGC_CDK_CDC2_CDK1_ST	P50570	DNM2	P06493	CDK1	T404	D406N	406	Missense	proximal	2	no	3.627	3.622	EPSD	TCGA;ICGC;COSMIC	3.158	Down-regulation
CMGC_CDK_CDC2_CDK1_ST	P50570	DNM2	P06493	CDK1	T404	A411S	411	Missense	distal	7	no	3.627	3.637	EPSD	TCGA;ICGC;COSMIC	3.158	Up-regulation
CMGC_CDK_CDC2_CDK1_ST	P50570	DNM2	P06493	CDK1	T404	T400M	400	Missense	distal	-4	no	3.627	3.538	EPSD	TCGA;ICGC;COSMIC	3.158	Down-regulation
CMGC_CDK_CDC2_CDK1_ST	P50570	DNM2	P06493	CDK1	T404	P405R	405	Missense	proximal	1	no	3.627	0.018	EPSD	TCGA	3.158	Loss
CMGC_CDK_CDC2_CDK1_ST	P50570	DNM2	P06493	CDK1	T404	R399W	399	Missense	distal	-5	no	3.627	3.652	EPSD	TCGA;ICGC	3.158	Up-regulation
CMGC_CDK_CDC2_CDK1_ST	O94761	RECQL4	P06493	CDK1	T93	P94S	94	Missense	proximal	1	no	3.723	0.539	EPSD	TCGA;ICGC;COSMIC	3.158	Loss
CMGC_CDK_CDC2_CDK1_ST	O94761	RECQL4	P06493	CDK1	S323	S323N	323	Missense	central	0	yes	3.327	0.000	EPSD	TCGA;ICGC;COSMIC	3.158	Loss
CMGC_CDK_CDC2_CDK1_ST	Q8WUF5	PPP1R13L	P06493	CDK1	T95	G92A	92	Missense	distal	-3	no	3.180	3.277	EPSD	TCGA	3.158	Up-regulation
CMGC_CDK_CDC2_CDK1_ST	Q8WUF5	PPP1R13L	P06493	CDK1	T95	G92C	92	Missense	distal	-3	no	3.180	3.219	EPSD	TCGA;ICGC;COSMIC	3.158	Up-regulation
CMGC_CDK_CDC2_CDK1_ST	Q8WUF5	PPP1R13L	P06493	CDK1	T173	R180C	180	Missense	distal	7	no	3.266	3.272	EPSD	TCGA;ICGC;COSMIC	3.158	Up-regulation
CMGC_CDK_CDC2_CDK1_ST	Q8WUF5	PPP1R13L	P06493	CDK1	S187	P188L	188	Missense	proximal	1	no	3.223	-0.463	EPSD	TCGA;ICGC	3.158	Loss
CMGC_CDK_CDC2_CDK1_ST	Q8WUF5	PPP1R13L	P06493	CDK1	S187	R180C	180	Missense	distal	-7	no	3.223	3.145	EPSD	TCGA;ICGC;COSMIC	3.158	Loss
CMGC_CDK_CDC2_CDK1_ST	Q8WUF5	PPP1R13L	P06493	CDK1	S616	K619E	619	Missense	distal	3	no	3.554	3.450	EPSD	TCGA;ICGC;COSMIC	3.158	Down-regulation
CMGC_CDK_CDC2_CDK1_ST	Q8WUF5	PPP1R13L	P06493	CDK1	S616	R612Q	612	Missense	distal	-4	no	3.554	3.572	EPSD	TCGA;ICGC;COSMIC;GDSC	3.158	Up-regulation
CMGC_CDK_CDC2_CDK1_ST	Q8WUF5	PPP1R13L	P06493	CDK1	S616	S616F	616	Missense	central	0	yes	3.554	0.000	EPSD	TCGA;ICGC;COSMIC	3.158	Loss
CMGC_CDK_CDC2_CDK1_ST	A6NKT7	RGPD3	P06493	CDK1	T800	A805G	805	Missense	distal	5	no	3.065	3.305	EPSD	TCGA;ICGC;COSMIC	3.158	Gain
CMGC_CDK_CDC2_CDK1_ST	A6NKT7	RGPD3	P06493	CDK1	T1153	A1148E	1148	Missense	distal	-5	no	3.362	3.438	EPSD	TCGA;ICGC;COSMIC	3.158	Up-regulation
CMGC_CDK_CDC2_CDK1_ST	A6NKT7	RGPD3	P06493	CDK1	T1153	K1150T	1150	Missense	distal	-3	no	3.362	3.404	EPSD	TCGA;ICGC;COSMIC	3.158	Up-regulation
CMGC_CDK_CDC2_CDK1_ST	A6NKT7	RGPD3	P06493	CDK1	T1153	A1148T	1148	Missense	distal	-5	no	3.362	3.383	EPSD	TCGA;ICGC;COSMIC	3.158	Up-regulation
CMGC_CDK_CDC2_CDK1_ST	A6NKT7	RGPD3	P06493	CDK1	T1153	E1159K	1159	Missense	distal	6	no	3.362	3.364	EPSD	TCGA;ICGC;COSMIC	3.158	Up-regulation
CMGC_CDK_CDC2_CDK1_ST	A6NKT7	RGPD3	P06493	CDK1	T1153	A1148S	1148	Missense	distal	-5	no	3.362	3.385	EPSD	TCGA;ICGC;COSMIC	3.158	Up-regulation
CMGC_CDK_CDC2_CDK1_ST	A6NKT7	RGPD3	P06493	CDK1	S1305	S1303C	1303	Missense	proximal	-2	no	3.427	3.444	EPSD	TCGA;ICGC;COSMIC	3.158	Up-regulation
CMGC_CDK_CDC2_CDK1_ST	A6NKT7	RGPD3	P06493	CDK1	S1305	K1304M	1304	Missense	proximal	-1	no	3.427	3.384	EPSD	TCGA;ICGC;COSMIC	3.158	Down-regulation
CMGC_CDK_CDC2_CDK1_ST	A6NKT7	RGPD3	P06493	CDK1	S1305	A1299S	1299	Missense	distal	-6	no	3.427	3.429	EPSD	TCGA;ICGC;COSMIC	3.158	Up-regulation
CMGC_CDK_CDC2_CDK1_ST	A6NKT7	RGPD3	P06493	CDK1	S1305	K1304R	1304	Missense	proximal	-1	no	3.427	3.358	EPSD	TCGA;ICGC;COSMIC	3.158	Down-regulation
CMGC_CDK_CDC2_CDK1_ST	A6NKT7	RGPD3	P06493	CDK1	S1305	S1303Y	1303	Missense	proximal	-2	no	3.427	3.478	EPSD	TCGA;ICGC;COSMIC	3.158	Up-regulation
CMGC_CDK_CDC2_CDK1_ST	A6NKT7	RGPD3	P06493	CDK1	S1305	A1307V	1307	Missense	proximal	2	no	3.427	3.450	EPSD	TCGA;ICGC	3.158	Up-regulation
CMGC_CDK_CDC2_CDK1_ST	A6NKT7	RGPD3	P06493	CDK1	S1305	A1299D	1299	Missense	distal	-6	no	3.427	3.439	EPSD	TCGA;ICGC	3.158	Up-regulation
CMGC_CDK_CDC2_CDK1_ST	A6NKT7	RGPD3	P06493	CDK1	S1305	A1299P	1299	Missense	distal	-6	no	3.427	3.431	EPSD	TCGA;ICGC;COSMIC	3.158	Up-regulation
CMGC_CDK_CDC2_CDK1_ST	A6NKT7	RGPD3	P06493	CDK1	T1412	R1410I	1410	Missense	proximal	-2	no	3.322	3.349	EPSD	TCGA;ICGC;COSMIC	3.158	Up-regulation
CMGC_CDK_CDC2_CDK1_ST	A6NKT7	RGPD3	P06493	CDK1	T1412	M1415I	1415	Missense	distal	3	no	3.322	3.263	EPSD	TCGA;ICGC;COSMIC	3.158	Down-regulation
CMGC_CDK_CDC2_CDK1_ST	A6NKT7	RGPD3	P06493	CDK1	T1412	D1414G	1414	Missense	proximal	2	no	3.322	3.335	EPSD	TCGA;ICGC	3.158	Up-regulation
CMGC_CDK_CDC2_CDK1_ST	A6NKT7	RGPD3	P06493	CDK1	T1475	L1473S	1473	Missense	proximal	-2	no	3.386	3.339	EPSD	TCGA;ICGC;COSMIC	3.158	Down-regulation
CMGC_CDK_CDC2_CDK1_ST	A6NKT7	RGPD3	P06493	CDK1	T1475	S1472F	1472	Missense	distal	-3	no	3.386	3.359	EPSD	TCGA;ICGC;COSMIC	3.158	Down-regulation
CMGC_CDK_CDC2_CDK1_ST	A6NKT7	RGPD3	P06493	CDK1	T1475	S1472Y	1472	Missense	distal	-3	no	3.386	3.354	EPSD	TCGA;ICGC;COSMIC	3.158	Down-regulation
CMGC_CDK_CDC2_CDK1_ST	A6NKT7	RGPD3	P06493	CDK1	T1638	E1642G	1642	Missense	distal	4	no	3.471	3.408	EPSD	TCGA;ICGC;COSMIC	3.158	Down-regulation
CMGC_CDK_CDC2_CDK1_ST	A6NKT7	RGPD3	P06493	CDK1	T1638	S1631L	1631	Missense	distal	-7	no	3.471	3.270	EPSD	TCGA;ICGC;COSMIC	3.158	Down-regulation
CMGC_CDK_CDC2_CDK1_ST	Q9UPP1	PHF8	P06493	CDK1	S175	T179N	179	Missense	distal	4	no	3.293	3.267	EPSD	TCGA;COSMIC	3.158	Down-regulation
CMGC_CDK_CDC2_CDK1_ST	Q9UPP1	PHF8	P06493	CDK1	S175	L173R	173	Missense	proximal	-2	no	3.293	3.313	EPSD	TCGA;COSMIC	3.158	Up-regulation
CMGC_CDK_CDC2_CDK1_ST	Q9UPP1	PHF8	P06493	CDK1	S175	M171L	171	Missense	distal	-4	no	3.293	3.179	EPSD	TCGA;COSMIC	3.158	Down-regulation
CMGC_CDK_CDC2_CDK1_ST	Q9UPP1	PHF8	P06493	CDK1	S175	T179I	179	Missense	distal	4	no	3.293	3.190	EPSD	TCGA;COSMIC	3.158	Down-regulation
CMGC_CDK_CDC2_CDK1_ST	Q9UPP1	PHF8	P06493	CDK1	T359	H355Y	355	Missense	distal	-4	no	3.531	3.502	EPSD	TCGA;COSMIC	3.158	Down-regulation
CMGC_CDK_CDC2_CDK1_ST	Q9UPP1	PHF8	P06493	CDK1	T359	F366V	366	Missense	distal	7	no	3.531	3.532	EPSD	TCGA;COSMIC	3.158	Up-regulation
CMGC_CDK_CDC2_CDK1_ST	Q9UPP1	PHF8	P06493	CDK1	S880	P878T	878	Missense	proximal	-2	no	3.385	3.472	EPSD	TCGA;COSMIC	3.158	Up-regulation
CMGC_CDK_CDC2_CDK1_ST	Q12778	FOXO1	P06493	CDK1	S329	M332I	332	Missense	distal	3	no	3.261	3.202	EPSD	TCGA;COSMIC	3.158	Down-regulation
CMGC_CDK_CDC2_CDK1_ST	Q12778	FOXO1	P06493	CDK1	S329	G326R	326	Missense	distal	-3	no	3.261	3.289	EPSD	TCGA;ICGC;COSMIC	3.158	Up-regulation
CMGC_CDK_CDC2_CDK1_ST	Q12778	FOXO1	P06493	CDK1	S329	S329L	329	Missense	central	0	yes	3.261	0.000	EPSD	TCGA;ICGC;COSMIC	3.158	Loss
CMGC_CDK_CDC2_CDK1_ST	Q12778	FOXO1	P06493	CDK1	S329	T323A	323	Missense	distal	-6	no	3.261	3.260	EPSD	TCGA;ICGC;COSMIC	3.158	Down-regulation
CMGC_CDK_CDC2_CDK1_ST	Q12778	FOXO1	P06493	CDK1	S394	L387I	387	Missense	distal	-7	no	3.109	3.158	EPSD	TCGA;ICGC;COSMIC	3.158	Gain
CMGC_CDK_CDC2_CDK1_ST	Q86WB0	ZC3HC1	P06493	CDK1	S24	R23C	23	Missense	proximal	-1	no	3.407	3.461	EPSD	TCGA;ICGC;COSMIC	3.158	Up-regulation
CMGC_CDK_CDC2_CDK1_ST	Q86WB0	ZC3HC1	P06493	CDK1	S62	A65V	65	Missense	distal	3	no	3.312	3.159	EPSD	TCGA;GDSC;CCLE	3.158	Down-regulation
CMGC_CDK_CDC2_CDK1_ST	Q86WB0	ZC3HC1	P06493	CDK1	S98	P99A	99	Missense	proximal	1	no	3.590	2.701	EPSD	TCGA;ICGC;COSMIC	3.158	Loss
CMGC_CDK_CDC2_CDK1_ST	Q86WB0	ZC3HC1	P06493	CDK1	S98	S98C	98	Missense	central	0	yes	3.590	0.000	EPSD	TCGA;ICGC;COSMIC	3.158	Loss
CMGC_CDK_CDC2_CDK1_ST	Q86WB0	ZC3HC1	P06493	CDK1	S98	A91T	91	Missense	distal	-7	no	3.590	3.583	EPSD	TCGA;ICGC	3.158	Down-regulation
CMGC_CDK_CDC2_CDK1_ST	O95235	KIF20A	P06493	CDK1	S867	S867I	867	Missense	central	0	yes	3.385	0.000	PhosphoSitePlus;EPSD	TCGA;ICGC;COSMIC	3.158	Loss
CMGC_CDK_CDC2_CDK1_ST	P30304	CDC25A	P06493	CDK1	S321	S317F	317	Missense	distal	-4	no	3.190	3.044	EPSD	TCGA;ICGC;COSMIC	3.158	Loss
CMGC_CDK_CDC2_CDK1_ST	P30304	CDC25A	P06493	CDK1	S361	S367C	367	Missense	distal	6	no	3.369	3.338	EPSD	TCGA;ICGC;COSMIC	3.158	Down-regulation
CMGC_CDK_CDC2_CDK1_ST	P30304	CDC25A	P06493	CDK1	S361	P362L	362	Missense	proximal	1	no	3.369	-0.317	EPSD	TCGA;ICGC;COSMIC	3.158	Loss
CMGC_CDK_CDC2_CDK1_ST	P30304	CDC25A	P06493	CDK1	S361	A366T	366	Missense	distal	5	no	3.369	3.432	EPSD	TCGA;ICGC;COSMIC	3.158	Up-regulation
CMGC_CDK_CDC2_CDK1_ST	P30304	CDC25A	P06493	CDK1	S361	Q355P	355	Missense	distal	-6	no	3.369	3.365	EPSD	TCGA;ICGC;COSMIC	3.158	Down-regulation
CMGC_CDK_CDC2_CDK1_ST	Q15398	DLGAP5	P06493	CDK1	T338	N334S	334	Missense	distal	-4	no	3.161	3.233	EPSD	TCGA;ICGC;COSMIC	3.158	Up-regulation
CMGC_CDK_CDC2_CDK1_ST	Q15398	DLGAP5	P06493	CDK1	T344	D351N	351	Missense	distal	7	no	3.371	3.365	EPSD	TCGA;ICGC;COSMIC	3.158	Down-regulation
CMGC_CDK_CDC2_CDK1_ST	Q15398	DLGAP5	P06493	CDK1	T344	E349K	349	Missense	distal	5	no	3.371	3.323	EPSD	TCGA;ICGC;COSMIC	3.158	Down-regulation
CMGC_CDK_CDC2_CDK1_ST	Q15398	DLGAP5	P06493	CDK1	T639	V643A	643	Missense	distal	4	no	3.313	3.448	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	3.158	Up-regulation
CMGC_CDK_CDC2_CDK1_ST	P52948	NUP98	P06493	CDK1	S839	S839L	839	Missense	central	0	yes	3.422	0.000	EPSD	TCGA;ICGC;COSMIC	3.158	Loss
CMGC_CDK_CDC2_CDK1_ST	Q12888	TP53BP1	P06493	CDK1	S1678	R1682W	1682	Missense	distal	4	no	3.993	3.920	PhosphoSitePlus;EPSD	TCGA;COSMIC	3.158	Down-regulation
CMGC_CDK_CDC2_CDK1_ST	Q12888	TP53BP1	P06493	CDK1	S1678	R1682Q	1682	Missense	distal	4	no	3.993	3.975	PhosphoSitePlus;EPSD	TCGA;COSMIC	3.158	Down-regulation
CMGC_CDK_CDC2_CDK1_ST	Q9BYG3	NIFK	P06493	CDK1	T223	T227N	227	Missense	distal	4	no	3.227	3.201	EPSD	TCGA;COSMIC	3.158	Down-regulation
CMGC_CDK_CDC2_CDK1_ST	O15350	TP73	P06493	CDK1	T167	G172V	172	Missense	distal	5	no	3.416	3.383	EPSD	TCGA;ICGC;COSMIC	3.158	Down-regulation
CMGC_CDK_CDC2_CDK1_ST	O15350	TP73	P06493	CDK1	S412	G419W	419	Missense	distal	7	no	3.757	3.745	EPSD	TCGA;COSMIC	3.158	Down-regulation
CMGC_CDK_CDC2_CDK1_ST	Q09666	AHNAK	P06493	CDK1	S93	R92L	92	Missense	proximal	-1	no	3.165	3.305	EPSD	TCGA;ICGC;COSMIC	3.158	Up-regulation
CMGC_CDK_CDC2_CDK1_ST	Q09666	AHNAK	P06493	CDK1	S93	T99P	99	Missense	distal	6	no	3.165	3.156	EPSD	TCGA;ICGC	3.158	Loss
CMGC_CDK_CDC2_CDK1_ST	Q09666	AHNAK	P06493	CDK1	S216	P217S	217	Missense	proximal	1	no	3.517	0.332	EPSD	TCGA;ICGC;COSMIC	3.158	Loss
CMGC_CDK_CDC2_CDK1_ST	Q09666	AHNAK	P06493	CDK1	S216	S212L	212	Missense	distal	-4	no	3.517	3.322	EPSD	TCGA;ICGC;COSMIC;GDSC	3.158	Down-regulation
CMGC_CDK_CDC2_CDK1_ST	Q09666	AHNAK	P06493	CDK1	S216	P217L	217	Missense	proximal	1	no	3.517	-0.170	EPSD	TCGA;ICGC;COSMIC	3.158	Loss
CMGC_CDK_CDC2_CDK1_ST	Q09666	AHNAK	P06493	CDK1	T490	K487E	487	Missense	distal	-3	no	4.009	4.021	EPSD	TCGA;ICGC;COSMIC	3.158	Up-regulation
CMGC_CDK_CDC2_CDK1_ST	Q09666	AHNAK	P06493	CDK1	T545	N547S	547	Missense	proximal	2	no	3.352	3.347	EPSD	TCGA;ICGC;COSMIC	3.158	Down-regulation
CMGC_CDK_CDC2_CDK1_ST	Q09666	AHNAK	P06493	CDK1	T545	L548P	548	Missense	distal	3	no	3.352	3.485	EPSD	TCGA;ICGC;COSMIC	3.158	Up-regulation
CMGC_CDK_CDC2_CDK1_ST	Q09666	AHNAK	P06493	CDK1	T694	I697F	697	Missense	distal	3	no	3.212	3.178	EPSD	TCGA	3.158	Down-regulation
CMGC_CDK_CDC2_CDK1_ST	Q09666	AHNAK	P06493	CDK1	T694	M699V	699	Missense	distal	5	no	3.212	3.293	EPSD	TCGA;ICGC	3.158	Up-regulation
CMGC_CDK_CDC2_CDK1_ST	Q09666	AHNAK	P06493	CDK1	T1192	P1186L	1186	Missense	distal	-6	no	3.414	3.441	EPSD	TCGA;ICGC;COSMIC	3.158	Up-regulation
CMGC_CDK_CDC2_CDK1_ST	Q09666	AHNAK	P06493	CDK1	T1192	P1193L	1193	Missense	proximal	1	no	3.414	-0.273	EPSD	TCGA;ICGC;COSMIC	3.158	Loss
CMGC_CDK_CDC2_CDK1_ST	Q09666	AHNAK	P06493	CDK1	T1192	P1186S	1186	Missense	distal	-6	no	3.414	3.412	EPSD	TCGA;ICGC;COSMIC	3.158	Down-regulation
CMGC_CDK_CDC2_CDK1_ST	Q09666	AHNAK	P06493	CDK1	T2309	E2304Q	2304	Missense	distal	-5	no	3.454	3.425	EPSD	TCGA;ICGC;COSMIC	3.158	Down-regulation
CMGC_CDK_CDC2_CDK1_ST	Q09666	AHNAK	P06493	CDK1	T2309	P2315S	2315	Missense	distal	6	no	3.454	3.461	EPSD	TCGA;ICGC	3.158	Up-regulation
CMGC_CDK_CDC2_CDK1_ST	Q09666	AHNAK	P06493	CDK1	T2832	M2837I	2837	Missense	distal	5	no	3.419	3.514	EPSD	TCGA;ICGC;COSMIC	3.158	Up-regulation
CMGC_CDK_CDC2_CDK1_ST	Q09666	AHNAK	P06493	CDK1	T2832	K2834N	2834	Missense	proximal	2	no	3.419	3.420	EPSD	TCGA;ICGC;COSMIC	3.158	Up-regulation
CMGC_CDK_CDC2_CDK1_ST	Q09666	AHNAK	P06493	CDK1	T2832	H2829L	2829	Missense	distal	-3	no	3.419	3.404	EPSD	TCGA;ICGC;COSMIC	3.158	Down-regulation
CMGC_CDK_CDC2_CDK1_ST	Q09666	AHNAK	P06493	CDK1	S3412	P3406H	3406	Missense	distal	-6	no	3.740	3.750	EPSD	TCGA;ICGC;COSMIC	3.158	Up-regulation
CMGC_CDK_CDC2_CDK1_ST	Q09666	AHNAK	P06493	CDK1	S3412	I3410T	3410	Missense	proximal	-2	no	3.740	3.607	EPSD	TCGA;ICGC;COSMIC	3.158	Down-regulation
CMGC_CDK_CDC2_CDK1_ST	Q09666	AHNAK	P06493	CDK1	S3412	S3416F	3416	Missense	distal	4	no	3.740	3.644	EPSD	TCGA;ICGC;COSMIC	3.158	Down-regulation
CMGC_CDK_CDC2_CDK1_ST	Q09666	AHNAK	P06493	CDK1	S3412	P3418S	3418	Missense	distal	6	no	3.740	3.748	EPSD	TCGA;ICGC;COSMIC	3.158	Up-regulation
CMGC_CDK_CDC2_CDK1_ST	Q09666	AHNAK	P06493	CDK1	T3716	I3721M	3721	Missense	distal	5	no	3.654	3.559	EPSD	TCGA;ICGC;COSMIC	3.158	Down-regulation
CMGC_CDK_CDC2_CDK1_ST	Q09666	AHNAK	P06493	CDK1	T4100	D4104N	4104	Missense	distal	4	no	3.736	3.762	EPSD	TCGA;ICGC;COSMIC	3.158	Up-regulation
CMGC_CDK_CDC2_CDK1_ST	Q09666	AHNAK	P06493	CDK1	T4100	P4101L	4101	Missense	proximal	1	no	3.736	0.049	EPSD	TCGA;ICGC	3.158	Loss
CMGC_CDK_CDC2_CDK1_ST	Q09666	AHNAK	P06493	CDK1	T4430	G4423V	4423	Missense	distal	-7	no	3.386	3.420	EPSD	TCGA;ICGC;COSMIC	3.158	Up-regulation
CMGC_CDK_CDC2_CDK1_ST	Q09666	AHNAK	P06493	CDK1	T4430	G4423D	4423	Missense	distal	-7	no	3.386	3.484	EPSD	TCGA;ICGC;COSMIC	3.158	Up-regulation
CMGC_CDK_CDC2_CDK1_ST	Q09666	AHNAK	P06493	CDK1	T4430	S4425I	4425	Missense	distal	-5	no	3.386	3.516	EPSD	TCGA;ICGC	3.158	Up-regulation
CMGC_CDK_CDC2_CDK1_ST	Q09666	AHNAK	P06493	CDK1	S4516	M4521V	4521	Missense	distal	5	no	3.413	3.493	EPSD	TCGA;ICGC;COSMIC	3.158	Up-regulation
CMGC_CDK_CDC2_CDK1_ST	Q09666	AHNAK	P06493	CDK1	S4516	P4517Q	4517	Missense	proximal	1	no	3.413	0.990	EPSD	TCGA;ICGC;COSMIC	3.158	Loss
CMGC_CDK_CDC2_CDK1_ST	Q09666	AHNAK	P06493	CDK1	T4564	P4565S	4565	Missense	proximal	1	no	3.625	0.441	EPSD	TCGA;ICGC;COSMIC	3.158	Loss
CMGC_CDK_CDC2_CDK1_ST	Q09666	AHNAK	P06493	CDK1	T4564	G4561D	4561	Missense	distal	-3	no	3.625	3.662	EPSD	TCGA;ICGC;CCLE	3.158	Up-regulation
CMGC_CDK_CDC2_CDK1_ST	Q09666	AHNAK	P06493	CDK1	S4960	D4959G	4959	Missense	proximal	-1	no	3.092	3.227	EPSD	TCGA;ICGC;COSMIC	3.158	Gain
CMGC_CDK_CDC2_CDK1_ST	Q09666	AHNAK	P06493	CDK1	S4986	A4989G	4989	Missense	distal	3	no	3.325	3.150	EPSD	TCGA;ICGC;COSMIC	3.158	Loss
CMGC_CDK_CDC2_CDK1_ST	Q09666	AHNAK	P06493	CDK1	S5110	K5103N	5103	Missense	distal	-7	no	3.499	3.552	EPSD	TCGA;ICGC;COSMIC	3.158	Up-regulation
CMGC_CDK_CDC2_CDK1_ST	Q09666	AHNAK	P06493	CDK1	S5110	L5113V	5113	Missense	distal	3	no	3.499	3.582	EPSD	TCGA;ICGC;COSMIC	3.158	Up-regulation
CMGC_CDK_CDC2_CDK1_ST	Q09666	AHNAK	P06493	CDK1	T5184	S5186F	5186	Missense	proximal	2	no	3.571	3.593	EPSD	TCGA;ICGC;COSMIC	3.158	Up-regulation
CMGC_CDK_CDC2_CDK1_ST	Q09666	AHNAK	P06493	CDK1	T5184	P5185S	5185	Missense	proximal	1	no	3.571	0.386	EPSD	TCGA;ICGC;COSMIC	3.158	Loss
CMGC_CDK_CDC2_CDK1_ST	Q09666	AHNAK	P06493	CDK1	T5184	A5191V	5191	Missense	distal	7	no	3.571	3.605	EPSD	TCGA;ICGC;COSMIC	3.158	Up-regulation
CMGC_CDK_CDC2_CDK1_ST	Q09666	AHNAK	P06493	CDK1	S5731	S5737C	5737	Missense	distal	6	no	3.540	3.509	EPSD	TCGA;ICGC;COSMIC	3.158	Down-regulation
CMGC_CDK_CDC2_CDK1_ST	Q09666	AHNAK	P06493	CDK1	S5731	S5737Y	5737	Missense	distal	6	no	3.540	3.501	EPSD	TCGA;ICGC;COSMIC	3.158	Down-regulation
CMGC_CDK_CDC2_CDK1_ST	Q09666	AHNAK	P06493	CDK1	S5763	K5767E	5767	Missense	distal	4	no	3.373	3.342	PhosphoSitePlus	TCGA;ICGC;COSMIC	3.158	Down-regulation
CMGC_CDK_CDC2_CDK1_ST	Q09666	AHNAK	P06493	CDK1	S5763	P5764L	5764	Missense	proximal	1	no	3.373	-0.313	PhosphoSitePlus	TCGA;ICGC;COSMIC	3.158	Loss
CMGC_CDK_CDC2_CDK1_ST	Q09666	AHNAK	P06493	CDK1	S5763	F5768S	5768	Missense	distal	5	no	3.373	3.207	PhosphoSitePlus	TCGA;ICGC;COSMIC	3.158	Down-regulation
CMGC_CDK_CDC2_CDK1_ST	Q09666	AHNAK	P06493	CDK1	T5794	T5798M	5798	Missense	distal	4	no	3.321	3.280	EPSD	TCGA;ICGC	3.158	Down-regulation
CMGC_CDK_CDC2_CDK1_ST	Q09666	AHNAK	P06493	CDK1	S5863	S5864P	5864	Missense	proximal	1	no	0.448	3.633	EPSD	TCGA;ICGC;COSMIC	3.158	Gain
CMGC_CDK_CDC2_CDK1_ST	Q96IF1	AJUBA	P06493	CDK1	S119	A115V	115	Missense	distal	-4	no	3.371	3.276	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	3.158	Down-regulation
CMGC_CDK_CDC2_CDK1_ST	P55211	CASP9	P06493	CDK1	S302	S307F	307	Missense	distal	5	no	3.188	3.355	EPSD	TCGA;ICGC;COSMIC	3.158	Up-regulation
CMGC_CDK_CDC2_CDK1_ST	Q13042	CDC16	P06493	CDK1	S560	P562L	562	Missense	proximal	2	no	3.693	3.713	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	3.158	Up-regulation
CMGC_CDK_CDC2_CDK1_ST	Q13042	CDC16	P06493	CDK1	S560	K553E	553	Missense	distal	-7	no	3.693	3.738	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	3.158	Up-regulation
CMGC_CDK_CDC2_CDK1_ST	Q13042	CDC16	P06493	CDK1	S560	P561R	561	Missense	proximal	1	no	3.693	0.084	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	3.158	Loss
CMGC_CDK_CDC2_CDK1_ST	Q13042	CDC16	P06493	CDK1	T581	L580R	580	Missense	proximal	-1	no	3.329	3.190	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	3.158	Down-regulation
CMGC_CDK_CDC2_CDK1_ST	Q13042	CDC16	P06493	CDK1	T581	T578M	578	Missense	distal	-3	no	3.329	3.311	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC;GDSC;CCLE	3.158	Down-regulation
CMGC_CDK_CDC2_CDK1_ST	O94782	USP1	P06493	CDK1	S16	R22I	22	Missense	distal	6	no	3.187	3.132	EPSD	TCGA;ICGC	3.158	Loss
CMGC_CDK_CDC2_CDK1_ST	O94782	USP1	P06493	CDK1	S67	K73N	73	Missense	distal	6	no	3.345	3.348	EPSD	TCGA;ICGC;COSMIC	3.158	Up-regulation
CMGC_CDK_CDC2_CDK1_ST	O94782	USP1	P06493	CDK1	S313	D309N	309	Missense	distal	-4	no	3.488	3.474	PhosphoSitePlus	TCGA;ICGC;COSMIC	3.158	Down-regulation
CMGC_CDK_CDC2_CDK1_ST	O94782	USP1	P06493	CDK1	S398	S398Y	398	Missense	central	0	yes	3.359	0.000	EPSD	TCGA;ICGC;COSMIC	3.158	Loss
CMGC_CDK_CDC2_CDK1_ST	O94782	USP1	P06493	CDK1	S398	G393R	393	Missense	distal	-5	no	3.359	3.291	EPSD	TCGA;ICGC;COSMIC	3.158	Down-regulation
CMGC_CDK_CDC2_CDK1_ST	O94782	USP1	P06493	CDK1	T404	S398Y	398	Missense	distal	-6	no	3.499	3.516	EPSD	TCGA;ICGC;COSMIC	3.158	Up-regulation
CMGC_CDK_CDC2_CDK1_ST	O94782	USP1	P06493	CDK1	S768	S766F	766	Missense	proximal	-2	no	3.795	3.863	EPSD	TCGA;ICGC;COSMIC	3.158	Up-regulation
CMGC_CDK_CDC2_CDK1_ST	O94782	USP1	P06493	CDK1	S768	N765K	765	Missense	distal	-3	no	3.795	3.774	EPSD	TCGA	3.158	Down-regulation
CMGC_CDK_CDC2_CDK1_ST	O94782	USP1	P06493	CDK1	S772	S766F	766	Missense	distal	-6	no	3.222	3.246	EPSD	TCGA;ICGC;COSMIC	3.158	Up-regulation
CMGC_CDK_CDC2_CDK1_ST	O94782	USP1	P06493	CDK1	S772	P777L	777	Missense	distal	5	no	3.222	3.407	EPSD	TCGA;ICGC	3.158	Up-regulation
CMGC_CDK_CDC2_CDK1_ST	O94782	USP1	P06493	CDK1	S772	N765K	765	Missense	distal	-7	no	3.222	3.169	EPSD	TCGA	3.158	Down-regulation
CMGC_CDK_CDC2_CDK1_ST	Q92574	TSC1	P06493	CDK1	T357	S361A	361	Missense	distal	4	no	3.356	3.416	EPSD	TCGA	3.158	Up-regulation
CMGC_CDK_CDC2_CDK1_ST	Q92574	TSC1	P06493	CDK1	T357	S361Y	361	Missense	distal	4	no	3.356	3.287	EPSD	TCGA;ICGC;COSMIC	3.158	Down-regulation
CMGC_CDK_CDC2_CDK1_ST	Q92574	TSC1	P06493	CDK1	T417	P412S	412	Missense	distal	-5	no	3.283	3.261	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	3.158	Down-regulation
CMGC_CDK_CDC2_CDK1_ST	Q92574	TSC1	P06493	CDK1	T417	Q413R	413	Missense	distal	-4	no	3.283	3.265	EPSD;PhosphoSitePlus	TCGA;ICGC	3.158	Down-regulation
CMGC_CDK_CDC2_CDK1_ST	Q92574	TSC1	P06493	CDK1	S565	S565N	565	Missense	central	0	yes	3.423	0.000	EPSD	TCGA;ICGC;COSMIC	3.158	Loss
CMGC_CDK_CDC2_CDK1_ST	Q92574	TSC1	P06493	CDK1	T582	S575F	575	Missense	distal	-7	no	3.782	3.635	EPSD	TCGA;ICGC;COSMIC	3.158	Down-regulation
CMGC_CDK_CDC2_CDK1_ST	Q92574	TSC1	P06493	CDK1	T582	P589S	589	Missense	distal	7	no	3.782	3.780	EPSD	TCGA;ICGC;COSMIC	3.158	Down-regulation
CMGC_CDK_CDC2_CDK1_ST	Q92574	TSC1	P06493	CDK1	S584	P589S	589	Missense	distal	5	no	3.520	3.491	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	3.158	Down-regulation
CMGC_CDK_CDC2_CDK1_ST	Q92574	TSC1	P06493	CDK1	S584	P591L	591	Missense	distal	7	no	3.520	3.547	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	3.158	Up-regulation
CMGC_CDK_CDC2_CDK1_ST	Q92574	TSC1	P06493	CDK1	S682	D675G	675	Missense	distal	-7	no	3.246	3.148	EPSD	TCGA;ICGC;COSMIC	3.158	Loss
CMGC_CDK_CDC2_CDK1_ST	Q92574	TSC1	P06493	CDK1	S682	P683S	683	Missense	proximal	1	no	3.246	0.061	EPSD	TCGA;ICGC;COSMIC	3.158	Loss
CMGC_CDK_CDC2_CDK1_ST	Q92574	TSC1	P06493	CDK1	S1141	P1143L	1143	Missense	proximal	2	no	3.628	3.649	EPSD	TCGA;ICGC;COSMIC	3.158	Up-regulation
CMGC_CDK_CDC2_CDK1_ST	Q92574	TSC1	P06493	CDK1	S1141	P1140L	1140	Missense	proximal	-1	no	3.628	3.778	EPSD	TCGA;ICGC;COSMIC	3.158	Up-regulation
CMGC_CDK_CDC2_CDK1_ST	Q92574	TSC1	P06493	CDK1	T1144	P1143L	1143	Missense	proximal	-1	no	3.323	3.474	EPSD	TCGA;ICGC;COSMIC	3.158	Up-regulation
CMGC_CDK_CDC2_CDK1_ST	Q92574	TSC1	P06493	CDK1	T1144	P1140L	1140	Missense	distal	-4	no	3.323	3.180	EPSD	TCGA;ICGC;COSMIC	3.158	Down-regulation
CMGC_CDK_CDC2_CDK1_ST	Q99661	KIF2C	P06493	CDK1	S589	D583N	583	Missense	distal	-6	no	3.234	3.233	EPSD	TCGA;COSMIC	3.158	Down-regulation
CMGC_CDK_CDC2_CDK1_ST	P56181	NDUFV3	P06493	CDK1	S105	S100I	100	Missense	distal	-5	no	3.567	3.697	PhosphoSitePlus	TCGA;ICGC;COSMIC	3.158	Up-regulation
CMGC_CDK_CDC2_CDK1_ST	Q01167	FOXK2	P06493	CDK1	S170	V175I	175	Missense	distal	5	no	3.505	3.519	EPSD	TCGA;ICGC;COSMIC	3.158	Up-regulation
CMGC_CDK_CDC2_CDK1_ST	Q01167	FOXK2	P06493	CDK1	S170	A174V	174	Missense	distal	4	no	3.505	3.370	EPSD	TCGA;ICGC;COSMIC	3.158	Down-regulation
CMGC_CDK_CDC2_CDK1_ST	Q01167	FOXK2	P06493	CDK1	S170	S170Y	170	Missense	central	0	yes	3.505	0.000	EPSD	TCGA;ICGC	3.158	Loss
CMGC_CDK_CDC2_CDK1_ST	Q01167	FOXK2	P06493	CDK1	S199	A206V	206	Missense	distal	7	no	3.231	3.265	EPSD	TCGA;ICGC;COSMIC	3.158	Up-regulation
CMGC_CDK_CDC2_CDK1_ST	Q01167	FOXK2	P06493	CDK1	S199	T201M	201	Missense	proximal	2	no	3.231	3.239	EPSD	TCGA;ICGC;COSMIC	3.158	Up-regulation
CMGC_CDK_CDC2_CDK1_ST	Q01167	FOXK2	P06493	CDK1	S213	A206V	206	Missense	distal	-7	no	3.683	3.531	EPSD	TCGA;ICGC;COSMIC	3.158	Down-regulation
CMGC_CDK_CDC2_CDK1_ST	Q01167	FOXK2	P06493	CDK1	S213	P214S	214	Missense	proximal	1	no	3.683	0.498	EPSD	TCGA;ICGC;COSMIC	3.158	Loss
CMGC_CDK_CDC2_CDK1_ST	Q01167	FOXK2	P06493	CDK1	T648	V641I	641	Missense	distal	-7	no	3.485	3.457	EPSD	TCGA;ICGC;COSMIC	3.158	Down-regulation
CMGC_CDK_CDC2_CDK1_ST	Q9NZJ0	DTL	P06493	CDK1	T464	L460V	460	Missense	distal	-4	no	3.142	3.214	PhosphoSitePlus	TCGA;COSMIC	3.158	Gain
CMGC_CDK_CDC2_CDK1_ST	Q9NZJ0	DTL	P06493	CDK1	S512	P517L	517	Missense	distal	5	no	3.104	3.289	EPSD	TCGA;COSMIC	3.158	Gain
CMGC_CDK_CDC2_CDK1_ST	Q9NZJ0	DTL	P06493	CDK1	S623	P622L	622	Missense	proximal	-1	no	3.844	3.994	EPSD	TCGA;COSMIC	3.158	Up-regulation
CMGC_CDK_CDC2_CDK1_ST	Q9NZJ0	DTL	P06493	CDK1	T702	P698L	698	Missense	distal	-4	no	3.191	3.047	EPSD	TCGA;COSMIC	3.158	Loss
CMGC_CDK_CDC2_CDK1_ST	P49915	GMPS	P06493	CDK1	T616	H619Y	619	Missense	distal	3	no	3.545	3.491	EPSD	TCGA;COSMIC	3.158	Down-regulation
CMGC_CDK_CDC2_CDK1_ST	P49915	GMPS	P06493	CDK1	T616	P612S	612	Missense	distal	-4	no	3.545	3.596	EPSD	TCGA;COSMIC	3.158	Up-regulation
CMGC_CDK_CDC2_CDK1_ST	O00418	EEF2K	P06493	CDK1	S74	E67K	67	Missense	distal	-7	no	3.347	3.302	EPSD	TCGA;ICGC;COSMIC	3.158	Down-regulation
CMGC_CDK_CDC2_CDK1_ST	O00418	EEF2K	P06493	CDK1	S74	H80Y	80	Missense	distal	6	no	3.347	3.321	EPSD	TCGA;ICGC;COSMIC	3.158	Down-regulation
CMGC_CDK_CDC2_CDK1_ST	O00418	EEF2K	P06493	CDK1	S74	R68W	68	Missense	distal	-6	no	3.347	3.355	EPSD	TCGA	3.158	Up-regulation
CMGC_CDK_CDC2_CDK1_ST	O00418	EEF2K	P06493	CDK1	S74	S74C	74	Missense	central	0	yes	3.347	0.000	EPSD	TCGA;ICGC;COSMIC	3.158	Loss
CMGC_CDK_CDC2_CDK1_ST	O00418	EEF2K	P06493	CDK1	S359	S366F	366	Missense	distal	7	no	3.244	3.266	PhosphoSitePlus	TCGA;ICGC;COSMIC	3.158	Up-regulation
CMGC_CDK_CDC2_CDK1_ST	O00418	EEF2K	P06493	CDK1	S359	S366C	366	Missense	distal	7	no	3.244	3.259	PhosphoSitePlus	TCGA;ICGC;COSMIC	3.158	Up-regulation
CMGC_CDK_CDC2_CDK1_ST	O00418	EEF2K	P06493	CDK1	T401	A400V	400	Missense	proximal	-1	no	3.389	3.589	EPSD	TCGA;ICGC;COSMIC	3.158	Up-regulation
CMGC_CDK_CDC2_CDK1_ST	O00418	EEF2K	P06493	CDK1	T401	S396F	396	Missense	distal	-5	no	3.389	3.498	EPSD	TCGA;ICGC;COSMIC	3.158	Up-regulation
CMGC_CDK_CDC2_CDK1_ST	Q9BXS6	NUSAP1	P06493	CDK1	S135	R128S	128	Missense	distal	-7	no	3.211	3.247	EPSD	TCGA;COSMIC	3.158	Up-regulation
CMGC_CDK_CDC2_CDK1_ST	Q9BXS6	NUSAP1	P06493	CDK1	S135	P134S	134	Missense	proximal	-1	no	3.211	3.160	EPSD	TCGA;ICGC;COSMIC	3.158	Down-regulation
CMGC_CDK_CDC2_CDK1_ST	Q9BXS6	NUSAP1	P06493	CDK1	S135	D138H	138	Missense	distal	3	no	3.211	3.259	EPSD	TCGA;COSMIC	3.158	Up-regulation
CMGC_CDK_CDC2_CDK1_ST	Q9BXS6	NUSAP1	P06493	CDK1	T244	P245L	245	Missense	proximal	1	no	3.338	-0.348	EPSD	TCGA;ICGC;COSMIC	3.158	Loss
CMGC_CDK_CDC2_CDK1_ST	Q9BXS6	NUSAP1	P06493	CDK1	T244	S243Y	243	Missense	proximal	-1	no	3.338	3.487	EPSD	TCGA;ICGC;COSMIC	3.158	Up-regulation
CMGC_CDK_CDC2_CDK1_ST	Q9BXS6	NUSAP1	P06493	CDK1	T300	R295C	295	Missense	distal	-5	no	3.540	3.573	PhosphoSitePlus;EPSD	TCGA;ICGC	3.158	Up-regulation
CMGC_CDK_CDC2_CDK1_ST	Q9BXS6	NUSAP1	P06493	CDK1	T338	S333F	333	Missense	distal	-5	no	3.132	3.242	EPSD;PhosphoSitePlus	TCGA;COSMIC	3.158	Gain
CMGC_CDK_CDC2_CDK1_ST	Q5TB30	DEPDC1	P06493	CDK1	T114	L115P	115	Missense	proximal	1	no	-0.331	3.355	EPSD	TCGA;ICGC;COSMIC	3.158	Gain
CMGC_CDK_CDC2_CDK1_ST	O00443	PIK3C2A	P06493	CDK1	T120	K113Q	113	Missense	distal	-7	no	3.322	3.404	EPSD	TCGA;ICGC;COSMIC	3.158	Up-regulation
CMGC_CDK_CDC2_CDK1_ST	O00443	PIK3C2A	P06493	CDK1	T120	T114A	114	Missense	distal	-6	no	3.322	3.321	EPSD	TCGA;ICGC;COSMIC	3.158	Down-regulation
CMGC_CDK_CDC2_CDK1_ST	O00443	PIK3C2A	P06493	CDK1	S124	S128L	128	Missense	distal	4	no	3.162	3.043	EPSD	TCGA;ICGC;COSMIC	3.158	Loss
CMGC_CDK_CDC2_CDK1_ST	O00443	PIK3C2A	P06493	CDK1	S1553	T1555A	1555	Missense	proximal	2	no	3.577	3.570	EPSD	TCGA;COSMIC	3.158	Down-regulation
CMGC_CDK_CDC2_CDK1_ST	O00443	PIK3C2A	P06493	CDK1	T1555	T1555A	1555	Missense	central	0	yes	3.624	0.000	EPSD	TCGA;COSMIC	3.158	Loss
CMGC_CDK_CDC2_CDK1_ST	Q9BW19	KIFC1	P06493	CDK1	S6	S6F	6	Missense	central	0	yes	3.475	0.000	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	3.158	Loss
CMGC_CDK_CDC2_CDK1_ST	Q9BW19	KIFC1	P06493	CDK1	S6	P3L	3	Missense	distal	-3	no	3.475	3.443	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	3.158	Down-regulation
CMGC_CDK_CDC2_CDK1_ST	O60701	UGDH	P06493	CDK1	S47	I42N	42	Missense	distal	-5	no	3.347	3.265	EPSD	TCGA;ICGC;COSMIC	3.158	Down-regulation
CMGC_CDK_CDC2_CDK1_ST	O60701	UGDH	P06493	CDK1	S47	S47Y	47	Missense	central	0	yes	3.347	0.000	EPSD	TCGA;ICGC	3.158	Loss
CMGC_CDK_CDC2_CDK1_ST	P20700	LMNB1	P06493	CDK1	S391	E384K	384	Missense	distal	-7	no	3.303	3.258	EPSD	TCGA;ICGC;COSMIC	3.158	Down-regulation
CMGC_CDK_CDC2_CDK1_ST	P20700	LMNB1	P06493	CDK1	T575	N580S	580	Missense	distal	5	no	3.452	3.412	EPSD	TCGA;ICGC;COSMIC	3.158	Down-regulation
CMGC_CDK_CDC2_CDK1_ST	P20700	LMNB1	P06493	CDK1	T575	S582R	582	Missense	distal	7	no	3.452	3.460	EPSD	TCGA	3.158	Up-regulation
CMGC_CDK_CDC2_CDK1_ST	P20700	LMNB1	P06493	CDK1	T575	N580T	580	Missense	distal	5	no	3.452	3.418	EPSD	TCGA;ICGC;COSMIC	3.158	Down-regulation
CMGC_CDK_CDC2_CDK1_ST	P20700	LMNB1	P06493	CDK1	T575	R581I	581	Missense	distal	6	no	3.452	3.396	EPSD	TCGA;ICGC	3.158	Down-regulation
CMGC_CDK_CDC2_CDK1_ST	Q01196	RUNX1	P06493	CDK1	S435	A440T	440	Missense	distal	5	no	3.236	3.299	EPSD	TCGA;ICGC;COSMIC	3.158	Up-regulation
CMGC_CDK_CDC2_CDK1_ST	Q01094	E2F1	P06493	CDK1	S121	E124Q	124	Missense	distal	3	no	3.476	3.549	EPSD	TCGA;ICGC;COSMIC	3.158	Up-regulation
CMGC_CDK_CDC2_CDK1_ST	Q01094	E2F1	P06493	CDK1	S121	R127H	127	Missense	distal	6	no	3.476	3.457	EPSD	TCGA;ICGC;COSMIC;GDSC;CCLE	3.158	Down-regulation
CMGC_CDK_CDC2_CDK1_ST	Q01094	E2F1	P06493	CDK1	T311	I306V	306	Missense	distal	-5	no	3.452	3.439	EPSD	TCGA;ICGC;COSMIC	3.158	Down-regulation
CMGC_CDK_CDC2_CDK1_ST	Q01094	E2F1	P06493	CDK1	S403	H406Y	406	Missense	distal	3	no	3.534	3.480	EPSD	TCGA;ICGC;COSMIC	3.158	Down-regulation
CMGC_CDK_CDC2_CDK1_ST	Q8IWB6	TEX14	P06493	CDK1	S168	R171Q	171	Missense	distal	3	no	3.816	3.767	EPSD	TCGA;ICGC	3.158	Down-regulation
CMGC_CDK_CDC2_CDK1_ST	Q8IWB6	TEX14	P06493	CDK1	S168	R171W	171	Missense	distal	3	no	3.816	3.687	EPSD	TCGA;ICGC;COSMIC	3.158	Down-regulation
CMGC_CDK_CDC2_CDK1_ST	Q8IWB6	TEX14	P06493	CDK1	S175	G181D	181	Missense	distal	6	no	3.135	3.165	EPSD	TCGA	3.158	Gain
CMGC_CDK_CDC2_CDK1_ST	Q8IWB6	TEX14	P06493	CDK1	T554	I560T	560	Missense	distal	6	no	3.347	3.398	EPSD	TCGA;COSMIC	3.158	Up-regulation
CMGC_CDK_CDC2_CDK1_ST	Q8IWB6	TEX14	P06493	CDK1	T554	E558K	558	Missense	distal	4	no	3.347	3.377	EPSD	TCGA;COSMIC	3.158	Up-regulation
CMGC_CDK_CDC2_CDK1_ST	Q8IWB6	TEX14	P06493	CDK1	T1277	S1275C	1275	Missense	proximal	-2	no	3.674	3.690	EPSD	TCGA;COSMIC	3.158	Up-regulation
CMGC_CDK_CDC2_CDK1_ST	Q8IWB6	TEX14	P06493	CDK1	T1277	E1276Q	1276	Missense	proximal	-1	no	3.674	3.631	EPSD	TCGA;COSMIC	3.158	Down-regulation
CMGC_CDK_CDC2_CDK1_ST	Q8IWB6	TEX14	P06493	CDK1	T1277	R1281I	1281	Missense	distal	4	no	3.674	3.561	EPSD	TCGA;COSMIC;GDSC	3.158	Down-regulation
CMGC_CDK_CDC2_CDK1_ST	Q8IWB6	TEX14	P06493	CDK1	T1277	S1274F	1274	Missense	distal	-3	no	3.674	3.646	EPSD	TCGA;COSMIC	3.158	Down-regulation
CMGC_CDK_CDC2_CDK1_ST	Q8IWB6	TEX14	P06493	CDK1	T1277	S1270Y	1270	Missense	distal	-7	no	3.674	3.559	EPSD	TCGA;COSMIC	3.158	Down-regulation
CMGC_CDK_CDC2_CDK1_ST	Q8IWB6	TEX14	P06493	CDK1	T1277	P1278S	1278	Missense	proximal	1	no	3.674	0.489	EPSD	TCGA;COSMIC	3.158	Loss
CMGC_CDK_CDC2_CDK1_ST	P98170	XIAP	P06493	CDK1	S40	A34S	34	Missense	distal	-6	no	3.582	3.584	PhosphoSitePlus	TCGA;ICGC;COSMIC	3.158	Up-regulation
CMGC_CDK_CDC2_CDK1_ST	P98170	XIAP	P06493	CDK1	S40	F33L	33	Missense	distal	-7	no	3.582	3.528	PhosphoSitePlus	TCGA;ICGC;COSMIC	3.158	Down-regulation
CMGC_CDK_CDC2_CDK1_ST	Q04637	EIF4G1	P06493	CDK1	S134	G139S	139	Missense	distal	5	no	3.596	3.414	EPSD	TCGA	3.158	Down-regulation
CMGC_CDK_CDC2_CDK1_ST	Q04637	EIF4G1	P06493	CDK1	S263	S267L	267	Missense	distal	4	no	3.571	3.452	EPSD	TCGA;COSMIC	3.158	Down-regulation
CMGC_CDK_CDC2_CDK1_ST	Q04637	EIF4G1	P06493	CDK1	S263	S260I	260	Missense	distal	-3	no	3.571	3.531	EPSD	TCGA	3.158	Down-regulation
CMGC_CDK_CDC2_CDK1_ST	P48200	IREB2	P06493	CDK1	S157	K160E	160	Missense	distal	3	no	3.545	3.441	PhosphoSitePlus	TCGA;ICGC;COSMIC	3.158	Down-regulation
CMGC_CDK_CDC2_CDK1_ST	P48200	IREB2	P06493	CDK1	T777	R779H	779	Missense	proximal	2	no	3.293	3.297	EPSD	TCGA;ICGC;COSMIC;CCLE	3.158	Up-regulation
CMGC_CDK_CDC2_CDK1_ST	Q9GZV5	WWTR1	P06493	CDK1	S89	S90P	90	Missense	proximal	1	no	0.058	3.242	EPSD	TCGA;ICGC;COSMIC	3.158	Gain
CMGC_CDK_CDC2_CDK1_ST	Q9GZV5	WWTR1	P06493	CDK1	S105	A111V	111	Missense	distal	6	no	3.387	3.339	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	3.158	Down-regulation
CMGC_CDK_CDC2_CDK1_ST	O60566	BUB1B	P06493	CDK1	T620	S619C	619	Missense	proximal	-1	no	3.148	3.265	EPSD	TCGA;COSMIC	3.158	Gain
CMGC_CDK_CDC2_CDK1_ST	Q15788	NCOA1	P06493	CDK1	S22	S22L	22	Missense	central	0	yes	3.582	0.000	EPSD	TCGA;ICGC;COSMIC	3.158	Loss
CMGC_CDK_CDC2_CDK1_ST	Q15788	NCOA1	P06493	CDK1	S517	V519I	519	Missense	proximal	2	no	3.156	3.161	EPSD	TCGA;ICGC;COSMIC;GDSC;CCLE	3.158	Gain
CMGC_CDK_CDC2_CDK1_ST	Q15788	NCOA1	P06493	CDK1	S517	S516R	516	Missense	proximal	-1	no	3.156	3.218	EPSD	TCGA;ICGC;COSMIC	3.158	Gain
CMGC_CDK_CDC2_CDK1_ST	Q15788	NCOA1	P06493	CDK1	S999	S999F	999	Missense	central	0	yes	3.621	0.000	EPSD	TCGA;ICGC;COSMIC	3.158	Loss
CMGC_CDK_CDC2_CDK1_ST	Q15788	NCOA1	P06493	CDK1	S1006	S999F	999	Missense	distal	-7	no	3.320	3.173	EPSD	TCGA;ICGC;COSMIC	3.158	Down-regulation
CMGC_CDK_CDC2_CDK1_ST	Q9UI09	NDUFA12	P06493	CDK1	T142	P140S	140	Missense	proximal	-2	no	3.480	3.607	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	3.158	Up-regulation
CMGC_CDK_CDC2_CDK1_ST	O94762	RECQL5	P06493	CDK1	T31	A37V	37	Missense	distal	6	no	3.369	3.321	EPSD	TCGA;COSMIC	3.158	Down-regulation
CMGC_CDK_CDC2_CDK1_ST	O94762	RECQL5	P06493	CDK1	S727	H722Y	722	Missense	distal	-5	no	3.147	3.175	PhosphoSitePlus	TCGA;ICGC;COSMIC	3.158	Gain
CMGC_CDK_CDC2_CDK1_ST	O94762	RECQL5	P06493	CDK1	S727	G724E	724	Missense	distal	-3	no	3.147	3.175	PhosphoSitePlus	TCGA;ICGC;COSMIC	3.158	Gain
CMGC_CDK_CDC2_CDK1_ST	O94762	RECQL5	P06493	CDK1	S954	Q951E	951	Missense	distal	-3	no	3.919	3.896	EPSD	TCGA;ICGC;COSMIC	3.158	Down-regulation
CMGC_CDK_CDC2_CDK1_ST	Q14807	KIF22	P06493	CDK1	S140	P141S	141	Missense	proximal	1	no	4.466	1.281	EPSD	TCGA;ICGC;COSMIC	3.158	Loss
CMGC_CDK_CDC2_CDK1_ST	Q14807	KIF22	P06493	CDK1	T463	L460V	460	Missense	distal	-3	no	3.490	3.502	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	3.158	Up-regulation
CMGC_CDK_CDC2_CDK1_ST	Q14807	KIF22	P06493	CDK1	T463	R468W	468	Missense	distal	5	no	3.490	3.603	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	3.158	Up-regulation
CMGC_CDK_CDC2_CDK1_ST	Q9Y6Q9	NCOA3	P06493	CDK1	S505	P499A	499	Missense	distal	-6	no	3.211	3.207	EPSD	TCGA;ICGC;COSMIC	3.158	Down-regulation
CMGC_CDK_CDC2_CDK1_ST	Q9Y6Q9	NCOA3	P06493	CDK1	S505	G511D	511	Missense	distal	6	no	3.211	3.241	EPSD	TCGA	3.158	Up-regulation
CMGC_CDK_CDC2_CDK1_ST	Q9Y6Q9	NCOA3	P06493	CDK1	S543	S542L	542	Missense	proximal	-1	no	3.666	3.867	EPSD	TCGA;ICGC;COSMIC	3.158	Up-regulation
CMGC_CDK_CDC2_CDK1_ST	Q9Y6Q9	NCOA3	P06493	CDK1	S543	S536F	536	Missense	distal	-7	no	3.666	3.519	EPSD	TCGA;ICGC;COSMIC	3.158	Down-regulation
CMGC_CDK_CDC2_CDK1_ST	Q9Y6Q9	NCOA3	P06493	CDK1	S543	S539F	539	Missense	distal	-4	no	3.666	3.519	EPSD	TCGA;ICGC;COSMIC	3.158	Down-regulation
CMGC_CDK_CDC2_CDK1_ST	Q9Y6Q9	NCOA3	P06493	CDK1	S551	P552L	552	Missense	proximal	1	no	3.569	-0.117	EPSD	TCGA;ICGC;COSMIC	3.158	Loss
CMGC_CDK_CDC2_CDK1_ST	P02545	LMNA	P06493	CDK1	S390	R388C	388	Missense	proximal	-2	no	3.258	3.208	EPSD;PhosphoSitePlus	TCGA;COSMIC	3.158	Down-regulation
CMGC_CDK_CDC2_CDK1_ST	P02545	LMNA	P06493	CDK1	S390	S395L	395	Missense	distal	5	no	3.258	3.472	EPSD;PhosphoSitePlus	TCGA;COSMIC	3.158	Up-regulation
CMGC_CDK_CDC2_CDK1_ST	P02545	LMNA	P06493	CDK1	S657	N660S	660	Missense	distal	3	no	3.356	3.351	EPSD	TCGA;COSMIC	3.158	Down-regulation
CMGC_CDK_CDC2_CDK1_ST	Q9UNH5	CDC14A	P06493	CDK1	S453	K449E	449	Missense	distal	-4	no	3.145	3.198	PhosphoSitePlus;EPSD	TCGA;COSMIC	3.158	Gain
CMGC_CDK_CDC2_CDK1_ST	P67870	CSNK2B	P06493	CDK1	S209	T213M	213	Missense	distal	4	no	4.026	3.985	PhosphoSitePlus	TCGA;ICGC	3.158	Down-regulation
CMGC_CDK_CDC2_CDK1_ST	P55273	CDKN2D	P06493	CDK1	S66	S73C	73	Missense	distal	7	no	3.975	3.989	EPSD	TCGA;ICGC;COSMIC	3.158	Up-regulation
CMGC_CDK_CDC2_CDK1_ST	P0C1Z6	TFPT	P06493	CDK1	S167	P168L	168	Missense	proximal	1	no	3.460	-0.227	EPSD	TCGA;COSMIC	3.158	Loss
CMGC_CDK_CDC2_CDK1_ST	P0C1Z6	TFPT	P06493	CDK1	S249	S252C	252	Missense	distal	3	no	3.222	3.173	EPSD	TCGA;COSMIC	3.158	Down-regulation
CMGC_CDK_CDC2_CDK1_ST	O43683	BUB1	P06493	CDK1	T452	M448V	448	Missense	distal	-4	no	3.285	3.244	EPSD	TCGA;ICGC;COSMIC	3.158	Down-regulation
CMGC_CDK_CDC2_CDK1_ST	O43683	BUB1	P06493	CDK1	T452	T452M	452	Missense	central	0	yes	3.285	0.000	EPSD	TCGA;ICGC;COSMIC;CCLE	3.158	Loss
CMGC_CDK_CDC2_CDK1_ST	O43683	BUB1	P06493	CDK1	T452	S459P	459	Missense	distal	7	no	3.285	3.287	EPSD	TCGA;ICGC;COSMIC	3.158	Up-regulation
CMGC_CDK_CDC2_CDK1_ST	O43683	BUB1	P06493	CDK1	S459	V462A	462	Missense	distal	3	no	3.196	3.349	EPSD	TCGA;ICGC;COSMIC	3.158	Up-regulation
CMGC_CDK_CDC2_CDK1_ST	O43683	BUB1	P06493	CDK1	S459	T452M	452	Missense	distal	-7	no	3.196	3.108	EPSD	TCGA;ICGC;COSMIC;CCLE	3.158	Loss
CMGC_CDK_CDC2_CDK1_ST	O43683	BUB1	P06493	CDK1	S459	S459P	459	Missense	central	0	yes	3.196	0.000	EPSD	TCGA;ICGC;COSMIC	3.158	Loss
CMGC_CDK_CDC2_CDK1_ST	O43683	BUB1	P06493	CDK1	T609	S602C	602	Missense	distal	-7	no	3.377	3.263	PhosphoSitePlus;EPSD	TCGA;ICGC;COSMIC	3.158	Down-regulation
CMGC_CDK_CDC2_CDK1_ST	Q14674	ESPL1	P06493	CDK1	S1153	S1153N	1153	Missense	central	0	yes	3.615	0.000	EPSD	TCGA;ICGC;COSMIC	3.158	Loss
CMGC_CDK_CDC2_CDK1_ST	Q14674	ESPL1	P06493	CDK1	S1153	D1147N	1147	Missense	distal	-6	no	3.615	3.613	EPSD	TCGA;ICGC;COSMIC	3.158	Down-regulation
CMGC_CDK_CDC2_CDK1_ST	Q14674	ESPL1	P06493	CDK1	T1210	S1205F	1205	Missense	distal	-5	no	3.327	3.436	EPSD	TCGA;ICGC;COSMIC	3.158	Up-regulation
CMGC_CDK_CDC2_CDK1_ST	Q14674	ESPL1	P06493	CDK1	T1346	P1349H	1349	Missense	distal	3	no	3.511	3.539	EPSD	TCGA;ICGC;COSMIC	3.158	Up-regulation
CMGC_CDK_CDC2_CDK1_ST	P54132	BLM	P06493	CDK1	T125	T125P	125	Missense	central	0	yes	3.172	0.000	EPSD	TCGA;ICGC;COSMIC	3.158	Loss
CMGC_CDK_CDC2_CDK1_ST	P54132	BLM	P06493	CDK1	T125	R132W	132	Missense	distal	7	no	3.172	3.180	EPSD	TCGA;ICGC;COSMIC	3.158	Up-regulation
CMGC_CDK_CDC2_CDK1_ST	P54132	BLM	P06493	CDK1	S706	C704R	704	Missense	proximal	-2	no	3.363	3.413	EPSD	TCGA	3.158	Up-regulation
CMGC_CDK_CDC2_CDK1_ST	P54132	BLM	P06493	CDK1	S714	P715L	715	Missense	proximal	1	no	3.348	-0.339	PhosphoSitePlus;EPSD	TCGA;ICGC;COSMIC	3.158	Loss
CMGC_CDK_CDC2_CDK1_ST	P39748	FEN1	P06493	CDK1	S187	F185L	185	Missense	proximal	-2	no	3.240	3.219	PhosphoSitePlus	TCGA;ICGC;COSMIC	3.158	Down-regulation
CMGC_CDK_CDC2_CDK1_ST	P39748	FEN1	P06493	CDK1	S187	R192Q	192	Missense	distal	5	no	3.240	3.264	PhosphoSitePlus	TCGA;ICGC;COSMIC	3.158	Up-regulation
CMGC_CDK_CDC2_CDK1_ST	P30305	CDC25B	P06493	CDK1	S249	V245M	245	Missense	distal	-4	no	3.152	3.193	EPSD	TCGA;COSMIC	3.158	Gain
CMGC_CDK_CDC2_CDK1_ST	P30305	CDC25B	P06493	CDK1	T355	E358K	358	Missense	distal	3	no	3.512	3.617	EPSD	TCGA;ICGC;COSMIC	3.158	Up-regulation
CMGC_CDK_CDC2_CDK1_ST	P30305	CDC25B	P06493	CDK1	S470	E464D	464	Missense	distal	-6	no	3.246	3.247	EPSD	TCGA;ICGC	3.158	Up-regulation
CMGC_CDK_CDC2_CDK1_ST	P30305	CDC25B	P06493	CDK1	S470	A463V	463	Missense	distal	-7	no	3.246	3.094	EPSD	TCGA;ICGC;COSMIC	3.158	Loss
CMGC_CDK_CDC2_CDK1_ST	O00571	DDX3X	P06493	CDK1	S125	R126P	126	Missense	proximal	1	no	-0.121	3.488	EPSD	TCGA;COSMIC	3.158	Gain
CMGC_CDK_CDC2_CDK1_ST	O00571	DDX3X	P06493	CDK1	T204	V206L	206	Missense	proximal	2	no	3.248	3.254	PhosphoSitePlus;EPSD	TCGA;COSMIC	3.158	Up-regulation
CMGC_CDK_CDC2_CDK1_ST	O00571	DDX3X	P06493	CDK1	T204	Y200S	200	Missense	distal	-4	no	3.248	3.347	PhosphoSitePlus;EPSD	TCGA;COSMIC	3.158	Up-regulation
CMGC_CDK_CDC2_CDK1_ST	O00571	DDX3X	P06493	CDK1	T204	R199C	199	Missense	distal	-5	no	3.248	3.281	PhosphoSitePlus;EPSD	TCGA;COSMIC	3.158	Up-regulation
CMGC_CDK_CDC2_CDK1_ST	O00571	DDX3X	P06493	CDK1	T204	K208N	208	Missense	distal	4	no	3.248	3.243	PhosphoSitePlus;EPSD	TCGA;COSMIC;CCLE	3.158	Down-regulation
CMGC_CDK_CDC2_CDK1_ST	O00571	DDX3X	P06493	CDK1	T204	R199P	199	Missense	distal	-5	no	3.248	3.213	PhosphoSitePlus;EPSD	TCGA;COSMIC;CCLE	3.158	Down-regulation
CMGC_CDK_CDC2_CDK1_ST	O00571	DDX3X	P06493	CDK1	T323	D329H	329	Missense	distal	6	no	3.494	3.505	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	3.158	Up-regulation
CMGC_CDK_CDC2_CDK1_ST	O00571	DDX3X	P06493	CDK1	T323	R326H	326	Missense	distal	3	no	3.494	3.402	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	3.158	Down-regulation
CMGC_CDK_CDC2_CDK1_ST	O00571	DDX3X	P06493	CDK1	S492	P493S	493	Missense	proximal	1	no	3.318	0.133	EPSD	TCGA;ICGC;COSMIC	3.158	Loss
CMGC_CDK_CDC2_CDK1_ST	Q9UGP4	LIMD1	P06493	CDK1	S197	G201S	201	Missense	distal	4	no	3.435	3.542	EPSD	TCGA;ICGC	3.158	Up-regulation
CMGC_CDK_CDC2_CDK1_ST	Q9UGP4	LIMD1	P06493	CDK1	S197	G191D	191	Missense	distal	-6	no	3.435	3.422	EPSD	TCGA;ICGC;COSMIC	3.158	Down-regulation
CMGC_CDK_CDC2_CDK1_ST	Q9UGP4	LIMD1	P06493	CDK1	T294	S296F	296	Missense	proximal	2	no	3.302	3.324	EPSD	TCGA;ICGC;COSMIC	3.158	Up-regulation
CMGC_CDK_CDC2_CDK1_ST	Q9UGP4	LIMD1	P06493	CDK1	S298	S296F	296	Missense	proximal	-2	no	3.116	3.183	EPSD	TCGA;ICGC;COSMIC	3.158	Gain
CMGC_CDK_CDC2_CDK1_ST	Q9UGP4	LIMD1	P06493	CDK1	S384	L388F	388	Missense	distal	4	no	3.807	3.829	EPSD	TCGA;ICGC;COSMIC	3.158	Up-regulation
CMGC_CDK_CDC2_CDK1_ST	Q9UGP4	LIMD1	P06493	CDK1	S384	S387N	387	Missense	distal	3	no	3.807	3.811	EPSD	TCGA;ICGC	3.158	Up-regulation
CMGC_CDK_CDC2_CDK1_ST	Q9UGP4	LIMD1	P06493	CDK1	S424	R428M	428	Missense	distal	4	no	3.218	3.167	EPSD;PhosphoSitePlus	TCGA;ICGC	3.158	Down-regulation
CMGC_CDK_CDC2_CDK1_ST	P26368	U2AF2	P06493	CDK1	T135	A131S	131	Missense	distal	-4	no	3.547	3.574	EPSD	TCGA;ICGC;COSMIC	3.158	Up-regulation
CMGC_CDK_CDC2_CDK1_ST	P26368	U2AF2	P06493	CDK1	T135	G129S	129	Missense	distal	-6	no	3.547	3.524	EPSD	TCGA;ICGC;COSMIC	3.158	Down-regulation
CMGC_CDK_CDC2_CDK1_ST	P26368	U2AF2	P06493	CDK1	S346	Q353E	353	Missense	distal	7	no	3.817	3.827	EPSD	TCGA;ICGC;COSMIC	3.158	Up-regulation
CMGC_CDK_CDC2_CDK1_ST	P26368	U2AF2	P06493	CDK1	S346	V345M	345	Missense	proximal	-1	no	3.817	3.759	EPSD	TCGA;COSMIC	3.158	Down-regulation
CMGC_CDK_CDC2_CDK1_ST	P10275	AR	P06493	CDK1	T282	E289K	289	Missense	distal	7	no	3.389	3.385	EPSD	TCGA;ICGC;COSMIC	3.158	Down-regulation
CMGC_CDK_CDC2_CDK1_ST	P10275	AR	P06493	CDK1	T282	R280C	280	Missense	proximal	-2	no	3.389	3.339	EPSD	TCGA;ICGC;COSMIC	3.158	Down-regulation
CMGC_CDK_CDC2_CDK1_ST	P10275	AR	P06493	CDK1	S310	E308K	308	Missense	proximal	-2	no	3.685	3.714	PhosphoSitePlus;EPSD	TCGA;COSMIC	3.158	Up-regulation
CMGC_CDK_CDC2_CDK1_ST	P10275	AR	P06493	CDK1	S310	Y316H	316	Missense	distal	6	no	3.685	3.711	PhosphoSitePlus;EPSD	TCGA;ICGC	3.158	Up-regulation
CMGC_CDK_CDC2_CDK1_ST	Q9BPX3	NCAPG	P06493	CDK1	T332	A336S	336	Missense	distal	4	no	3.510	3.450	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	3.158	Down-regulation
CMGC_CDK_CDC2_CDK1_ST	Q9BPX3	NCAPG	P06493	CDK1	T332	I326S	326	Missense	distal	-6	no	3.510	3.487	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	3.158	Down-regulation
CMGC_CDK_CDC2_CDK1_ST	Q9BPX3	NCAPG	P06493	CDK1	S844	Y850H	850	Missense	distal	6	no	3.368	3.394	EPSD	TCGA;ICGC;COSMIC	3.158	Up-regulation
CMGC_CDK_CDC2_CDK1_ST	Q14739	LBR	P06493	CDK1	S357	N354S	354	Missense	distal	-3	no	3.481	3.498	EPSD	TCGA	3.158	Up-regulation
CMGC_CDK_CDC2_CDK1_ST	Q14739	LBR	P06493	CDK1	S357	G362R	362	Missense	distal	5	no	3.481	3.289	EPSD	TCGA;ICGC;COSMIC	3.158	Down-regulation
CMGC_CDK_CDC2_CDK1_ST	Q9NRI5	DISC1	P06493	CDK1	S241	P242L	242	Missense	proximal	1	no	3.205	-0.481	EPSD	TCGA;ICGC;COSMIC	3.158	Loss
CMGC_CDK_CDC2_CDK1_ST	Q02750	MAP2K1	P06493	CDK1	T55	Q56P	56	Missense	proximal	1	no	1.505	3.928	EPSD	TCGA;ICGC;COSMIC;GDSC;CCLE	3.158	Gain
CMGC_CDK_CDC2_CDK1_ST	Q02750	MAP2K1	P06493	CDK1	S231	L235H	235	Missense	distal	4	no	3.451	3.547	EPSD	TCGA;ICGC;COSMIC	3.158	Up-regulation
CMGC_CDK_CDC2_CDK1_ST	Q02750	MAP2K1	P06493	CDK1	S231	S231L	231	Missense	central	0	yes	3.451	0.000	EPSD	TCGA;ICGC;COSMIC	3.158	Loss
CMGC_CDK_CDC2_CDK1_ST	Q02750	MAP2K1	P06493	CDK1	S231	V224M	224	Missense	distal	-7	no	3.451	3.508	EPSD	TCGA;ICGC;COSMIC	3.158	Up-regulation
CMGC_CDK_CDC2_CDK1_ST	Q02750	MAP2K1	P06493	CDK1	S231	R227K	227	Missense	distal	-4	no	3.451	3.404	EPSD	TCGA;ICGC;COSMIC	3.158	Down-regulation
CMGC_CDK_CDC2_CDK1_ST	Q02750	MAP2K1	P06493	CDK1	T286	P290S	290	Missense	distal	4	no	3.180	3.177	PhosphoSitePlus;EPSD	TCGA;ICGC	3.158	Down-regulation
CMGC_CDK_CDC2_CDK1_ST	Q02750	MAP2K1	P06493	CDK1	T292	G294R	294	Missense	proximal	2	no	3.399	3.383	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	3.158	Down-regulation
CMGC_CDK_CDC2_CDK1_ST	Q02750	MAP2K1	P06493	CDK1	T292	G294V	294	Missense	proximal	2	no	3.399	3.392	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	3.158	Down-regulation
CMGC_CDK_CDC2_CDK1_ST	Q02750	MAP2K1	P06493	CDK1	T292	G294E	294	Missense	proximal	2	no	3.399	3.386	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	3.158	Down-regulation
CMGC_CDK_CDC2_CDK1_ST	Q02750	MAP2K1	P06493	CDK1	T292	P290S	290	Missense	proximal	-2	no	3.399	3.525	EPSD;PhosphoSitePlus	TCGA;ICGC	3.158	Up-regulation
CMGC_CDK_CDC2_CDK1_ST	P27816	MAP4	P06493	CDK1	S384	K377N	377	Missense	distal	-7	no	3.415	3.468	EPSD	TCGA;COSMIC	3.158	Up-regulation
CMGC_CDK_CDC2_CDK1_ST	P27816	MAP4	P06493	CDK1	S384	M388V	388	Missense	distal	4	no	3.415	3.373	EPSD	TCGA;ICGC;COSMIC	3.158	Down-regulation
CMGC_CDK_CDC2_CDK1_ST	P27816	MAP4	P06493	CDK1	T571	D575G	575	Missense	distal	4	no	3.328	3.265	EPSD	TCGA;ICGC;COSMIC	3.158	Down-regulation
CMGC_CDK_CDC2_CDK1_ST	P27816	MAP4	P06493	CDK1	S624	E626K	626	Missense	proximal	2	no	3.543	3.539	EPSD	TCGA;ICGC	3.158	Down-regulation
CMGC_CDK_CDC2_CDK1_ST	Q8IX90	SKA3	P06493	CDK1	T190	L197P	197	Missense	distal	7	no	3.325	3.297	EPSD	TCGA;ICGC;COSMIC	3.158	Down-regulation
CMGC_CDK_CDC2_CDK1_ST	Q8IX90	SKA3	P06493	CDK1	T190	S196P	196	Missense	distal	6	no	3.325	3.317	EPSD	TCGA;ICGC	3.158	Down-regulation
CMGC_CDK_CDC2_CDK1_ST	Q8IX90	SKA3	P06493	CDK1	S196	L197P	197	Missense	proximal	1	no	-0.370	3.316	EPSD	TCGA;ICGC;COSMIC	3.158	Gain
CMGC_CDK_CDC2_CDK1_ST	Q8IX90	SKA3	P06493	CDK1	T203	L197P	197	Missense	distal	-6	no	3.771	3.744	EPSD	TCGA;ICGC;COSMIC	3.158	Down-regulation
CMGC_CDK_CDC2_CDK1_ST	Q8IX90	SKA3	P06493	CDK1	T203	S196P	196	Missense	distal	-7	no	3.771	3.731	EPSD	TCGA;ICGC	3.158	Down-regulation
CMGC_CDK_CDC2_CDK1_ST	Q8IX90	SKA3	P06493	CDK1	T203	M210I	210	Missense	distal	7	no	3.771	3.786	EPSD	TCGA;ICGC;COSMIC	3.158	Up-regulation
CMGC_CDK_CDC2_CDK1_ST	Q8IX90	SKA3	P06493	CDK1	T358	P362R	362	Missense	distal	4	no	3.753	3.767	PhosphoSitePlus;EPSD	TCGA;ICGC;COSMIC	3.158	Up-regulation
CMGC_CDK_CDC2_CDK1_ST	Q8IX90	SKA3	P06493	CDK1	T358	L355M	355	Missense	distal	-3	no	3.753	3.771	PhosphoSitePlus;EPSD	TCGA;ICGC	3.158	Up-regulation
CMGC_CDK_CDC2_CDK1_ST	O60610	DIAPH1	P06493	CDK1	T768	G766R	766	Missense	proximal	-2	no	3.179	3.157	PhosphoSitePlus	TCGA;COSMIC	3.158	Loss
CMGC_CDK_CDC2_CDK1_ST	O60610	DIAPH1	P06493	CDK1	T768	K770Q	770	Missense	proximal	2	no	3.179	3.177	PhosphoSitePlus	TCGA;COSMIC	3.158	Down-regulation
CMGC_CDK_CDC2_CDK1_ST	Q12959	DLG1	P06493	CDK1	T115	P116L	116	Missense	proximal	1	no	3.222	-0.465	EPSD	TCGA;ICGC;COSMIC	3.158	Loss
CMGC_CDK_CDC2_CDK1_ST	Q12959	DLG1	P06493	CDK1	T115	P116S	116	Missense	proximal	1	no	3.222	0.037	EPSD	TCGA;ICGC;COSMIC	3.158	Loss
CMGC_CDK_CDC2_CDK1_ST	Q12959	DLG1	P06493	CDK1	S122	P116L	116	Missense	distal	-6	no	3.534	3.561	EPSD	TCGA;ICGC;COSMIC	3.158	Up-regulation
CMGC_CDK_CDC2_CDK1_ST	Q12959	DLG1	P06493	CDK1	S122	P116S	116	Missense	distal	-6	no	3.534	3.533	EPSD	TCGA;ICGC;COSMIC	3.158	Down-regulation
CMGC_CDK_CDC2_CDK1_ST	Q12959	DLG1	P06493	CDK1	S158	A165S	165	Missense	distal	7	no	3.415	3.425	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	3.158	Up-regulation
CMGC_CDK_CDC2_CDK1_ST	Q12959	DLG1	P06493	CDK1	S448	A442V	442	Missense	distal	-6	no	3.218	3.239	EPSD	TCGA;COSMIC	3.158	Up-regulation
CMGC_CDK_CDC2_CDK1_ST	P42898	MTHFR	P06493	CDK1	T34	E40K	40	Missense	distal	6	no	3.355	3.357	PhosphoSitePlus	TCGA;ICGC;COSMIC	3.158	Up-regulation
CMGC_CDK_CDC2_CDK1_ST	P42898	MTHFR	P06493	CDK1	T34	S30L	30	Missense	distal	-4	no	3.355	3.161	PhosphoSitePlus	TCGA;ICGC;COSMIC	3.158	Down-regulation
CMGC_CDK_CDC2_CDK1_ST	P42898	MTHFR	P06493	CDK1	T34	R41W	41	Missense	distal	7	no	3.355	3.363	PhosphoSitePlus	TCGA;ICGC;COSMIC;CCLE	3.158	Up-regulation
CMGC_CDK_CDC2_CDK1_ST	Q9UPU5	USP24	P06493	CDK1	S914	V908I	908	Missense	distal	-6	no	3.631	3.634	EPSD	TCGA;ICGC;COSMIC	3.158	Up-regulation
CMGC_CDK_CDC2_CDK1_ST	Q9UPU5	USP24	P06493	CDK1	S914	V908A	908	Missense	distal	-6	no	3.631	3.609	EPSD	TCGA;ICGC;COSMIC	3.158	Down-regulation
CMGC_CDK_CDC2_CDK1_ST	Q9UPU5	USP24	P06493	CDK1	S1141	S1143F	1143	Missense	proximal	2	no	3.540	3.562	EPSD	TCGA;COSMIC	3.158	Up-regulation
CMGC_CDK_CDC2_CDK1_ST	Q9UPU5	USP24	P06493	CDK1	S1141	S1136F	1136	Missense	distal	-5	no	3.540	3.650	EPSD	TCGA;ICGC;COSMIC	3.158	Up-regulation
CMGC_CDK_CDC2_CDK1_ST	Q9UPU5	USP24	P06493	CDK1	T1289	S1294F	1294	Missense	distal	5	no	3.567	3.734	EPSD	TCGA;COSMIC	3.158	Up-regulation
CMGC_CDK_CDC2_CDK1_ST	Q9UPU5	USP24	P06493	CDK1	S2077	S2077L	2077	Missense	central	0	yes	3.223	0.000	EPSD	TCGA;ICGC;COSMIC	3.158	Loss
CMGC_CDK_CDC2_CDK1_ST	Q9UPU5	USP24	P06493	CDK1	S2077	R2083Q	2083	Missense	distal	6	no	3.223	3.206	EPSD	TCGA;COSMIC	3.158	Down-regulation
CMGC_CDK_CDC2_CDK1_ST	Q9UPU5	USP24	P06493	CDK1	S2081	S2077L	2077	Missense	distal	-4	no	3.333	3.139	EPSD	TCGA;ICGC;COSMIC	3.158	Loss
CMGC_CDK_CDC2_CDK1_ST	Q9UPU5	USP24	P06493	CDK1	S2081	R2083Q	2083	Missense	proximal	2	no	3.333	3.329	EPSD	TCGA;COSMIC	3.158	Down-regulation
CMGC_CDK_CDC2_CDK1_ST	Q9UPU5	USP24	P06493	CDK1	S2081	N2088D	2088	Missense	distal	7	no	3.333	3.338	EPSD	TCGA;ICGC	3.158	Up-regulation
CMGC_CDK_CDC2_CDK1_ST	P24928	POLR2A	P06493	CDK1	T368	P369T	369	Missense	proximal	1	no	3.522	1.089	EPSD	TCGA;ICGC;COSMIC	3.158	Loss
CMGC_CDK_CDC2_CDK1_ST	P24928	POLR2A	P06493	CDK1	T543	R546H	546	Missense	distal	3	no	3.231	3.138	EPSD	TCGA;ICGC;COSMIC	3.158	Loss
CMGC_CDK_CDC2_CDK1_ST	P24928	POLR2A	P06493	CDK1	T1518	A1516V	1516	Missense	proximal	-2	no	3.212	3.377	EPSD	TCGA;ICGC	3.158	Up-regulation
CMGC_CDK_CDC2_CDK1_ST	P24928	POLR2A	P06493	CDK1	T1518	M1517V	1517	Missense	proximal	-1	no	3.212	3.269	EPSD	TCGA;ICGC	3.158	Up-regulation
CMGC_CDK_CDC2_CDK1_ST	P24928	POLR2A	P06493	CDK1	S1948	S1944F	1944	Missense	distal	-4	no	3.341	3.194	EPSD	TCGA;ICGC	3.158	Down-regulation
CMGC_CDK_CDC2_CDK1_ST	P24928	POLR2A	P06493	CDK1	S1962	I1961M	1961	Missense	proximal	-1	no	3.683	3.573	EPSD	TCGA;ICGC	3.158	Down-regulation
CMGC_CDK_CDC2_CDK1_ST	Q8N122	RPTOR	P06493	CDK1	S877	S877F	877	Missense	central	0	yes	3.669	0.000	EPSD	TCGA;COSMIC	3.158	Loss
CMGC_CDK_CDC2_CDK1_ST	Q8N122	RPTOR	P06493	CDK1	S877	P879L	879	Missense	proximal	2	no	3.669	3.690	EPSD	TCGA;COSMIC	3.158	Up-regulation
CMGC_CDK_CDC2_CDK1_ST	Q96RL1	UIMC1	P06493	CDK1	S463	P464L	464	Missense	proximal	1	no	3.281	-0.406	EPSD	TCGA;ICGC;COSMIC	3.158	Loss
CMGC_CDK_CDC2_CDK1_ST	Q9UJX5	ANAPC4	P06493	CDK1	S29	S29W	29	Missense	central	0	yes	3.587	0.000	EPSD	TCGA;ICGC;COSMIC	3.158	Loss
CMGC_CDK_CDC2_CDK1_ST	Q53EZ4	CEP55	P06493	CDK1	S436	L437P	437	Missense	proximal	1	no	-0.258	3.429	EPSD	TCGA;ICGC;COSMIC	3.158	Gain
CMGC_CDK_CDC2_CDK1_ST	P50613	CDK7	P06493	CDK1	T110	N105T	105	Missense	distal	-5	no	3.186	3.136	EPSD	TCGA;COSMIC	3.158	Loss
CMGC_CDK_CDC2_CDK1_ST	P50613	CDK7	P06493	CDK1	T110	K115N	115	Missense	distal	5	no	3.186	3.194	EPSD	TCGA	3.158	Up-regulation
CMGC_CDK_CDC2_CDK1_ST	P50613	CDK7	P06493	CDK1	S164	A159T	159	Missense	distal	-5	no	3.375	3.397	EPSD;PhosphoSitePlus	TCGA;COSMIC	3.158	Up-regulation
CMGC_CDK_CDC2_CDK1_ST	P50613	CDK7	P06493	CDK1	S164	P165R	165	Missense	proximal	1	no	3.375	-0.234	EPSD;PhosphoSitePlus	TCGA;COSMIC	3.158	Loss
CMGC_CDK_CDC2_CDK1_ST	P50613	CDK7	P06493	CDK1	S164	N166D	166	Missense	proximal	2	no	3.375	3.380	EPSD;PhosphoSitePlus	TCGA;COSMIC	3.158	Up-regulation
CMGC_CDK_CDC2_CDK1_ST	P50613	CDK7	P06493	CDK1	T231	E234K	234	Missense	distal	3	no	3.153	3.257	EPSD	TCGA;COSMIC	3.158	Gain
CMGC_CDK_CDC2_CDK1_ST	Q14C86	GAPVD1	P06493	CDK1	T80	Q81P	81	Missense	proximal	1	no	1.167	3.590	EPSD	TCGA;ICGC;COSMIC	3.158	Gain
CMGC_CDK_CDC2_CDK1_ST	Q14C86	GAPVD1	P06493	CDK1	S227	R225S	225	Missense	proximal	-2	no	3.723	3.656	EPSD	TCGA;ICGC;COSMIC;GDSC;CCLE	3.158	Down-regulation
CMGC_CDK_CDC2_CDK1_ST	Q14C86	GAPVD1	P06493	CDK1	S227	P228L	228	Missense	proximal	1	no	3.723	0.036	EPSD	TCGA;ICGC;COSMIC	3.158	Loss
CMGC_CDK_CDC2_CDK1_ST	Q14C86	GAPVD1	P06493	CDK1	S227	R225M	225	Missense	proximal	-2	no	3.723	3.673	EPSD	TCGA;ICGC;COSMIC	3.158	Down-regulation
CMGC_CDK_CDC2_CDK1_ST	Q14C86	GAPVD1	P06493	CDK1	T390	S394Y	394	Missense	distal	4	no	3.188	3.119	EPSD	TCGA;ICGC;COSMIC	3.158	Loss
CMGC_CDK_CDC2_CDK1_ST	Q14C86	GAPVD1	P06493	CDK1	T390	E389D	389	Missense	proximal	-1	no	3.188	3.180	EPSD	TCGA;ICGC	3.158	Down-regulation
CMGC_CDK_CDC2_CDK1_ST	Q14C86	GAPVD1	P06493	CDK1	S466	P471L	471	Missense	distal	5	no	3.023	3.208	EPSD	TCGA;ICGC;COSMIC	3.158	Gain
CMGC_CDK_CDC2_CDK1_ST	Q14C86	GAPVD1	P06493	CDK1	S801	D805G	805	Missense	distal	4	no	3.215	3.152	EPSD	TCGA;ICGC;COSMIC	3.158	Loss
CMGC_CDK_CDC2_CDK1_ST	Q14C86	GAPVD1	P06493	CDK1	S801	S798Y	798	Missense	distal	-3	no	3.215	3.182	EPSD	TCGA;ICGC	3.158	Down-regulation
CMGC_CDK_CDC2_CDK1_ST	P06748	NPM1	P06493	CDK1	S10	D3Y	3	Missense	distal	-7	no	3.465	3.411	EPSD	TCGA	3.158	Down-regulation
CMGC_CDK_CDC2_CDK1_ST	P06748	NPM1	P06493	CDK1	S10	L12M	12	Missense	proximal	2	no	3.465	3.451	EPSD	TCGA;ICGC;COSMIC	3.158	Down-regulation
CMGC_CDK_CDC2_CDK1_ST	P06748	NPM1	P06493	CDK1	S10	S4L	4	Missense	distal	-6	no	3.465	3.493	EPSD	TCGA;ICGC;COSMIC	3.158	Up-regulation
CMGC_CDK_CDC2_CDK1_ST	P06748	NPM1	P06493	CDK1	S70	K73Q	73	Missense	distal	3	no	3.554	3.523	PhosphoSitePlus;EPSD	TCGA;ICGC;COSMIC	3.158	Down-regulation
CMGC_CDK_CDC2_CDK1_ST	P06748	NPM1	P06493	CDK1	T95	E93K	93	Missense	proximal	-2	no	3.457	3.485	EPSD	TCGA;ICGC	3.158	Up-regulation
CMGC_CDK_CDC2_CDK1_ST	P06748	NPM1	P06493	CDK1	T219	D213N	213	Missense	distal	-6	no	3.192	3.190	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	3.158	Down-regulation
CMGC_CDK_CDC2_CDK1_ST	Q9Y2I6	NINL	P06493	CDK1	S185	S185R	185	Missense	central	0	yes	3.334	0.000	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	3.158	Loss
CMGC_CDK_CDC2_CDK1_ST	Q9Y2I6	NINL	P06493	CDK1	S585	H584L	584	Missense	proximal	-1	no	3.094	3.210	EPSD	TCGA;ICGC;COSMIC	3.158	Gain
CMGC_CDK_CDC2_CDK1_ST	Q9Y2I6	NINL	P06493	CDK1	S589	H584L	584	Missense	distal	-5	no	3.199	3.289	PhosphoSitePlus;EPSD	TCGA;ICGC;COSMIC	3.158	Up-regulation
CMGC_CDK_CDC2_CDK1_ST	Q9Y2I6	NINL	P06493	CDK1	S589	R593C	593	Missense	distal	4	no	3.199	3.134	PhosphoSitePlus;EPSD	TCGA;ICGC;COSMIC	3.158	Loss
CMGC_CDK_CDC2_CDK1_ST	Q9Y2I6	NINL	P06493	CDK1	S589	R595Q	595	Missense	distal	6	no	3.199	3.182	PhosphoSitePlus;EPSD	TCGA;ICGC;COSMIC	3.158	Down-regulation
CMGC_CDK_CDC2_CDK1_ST	Q8NHV4	NEDD1	P06493	CDK1	S411	S411G	411	Missense	central	0	yes	3.989	0.000	EPSD;PhosphoSitePlus	TCGA;COSMIC	3.158	Loss
CMGC_CDK_CDC2_CDK1_ST	Q9BTA9	WAC	P06493	CDK1	S64	M58T	58	Missense	distal	-6	no	3.405	3.393	EPSD	TCGA;COSMIC	3.158	Down-regulation
CMGC_CDK_CDC2_CDK1_ST	Q9BTA9	WAC	P06493	CDK1	S64	K57R	57	Missense	distal	-7	no	3.405	3.481	EPSD	TCGA;ICGC	3.158	Up-regulation
CMGC_CDK_CDC2_CDK1_ST	Q9BTA9	WAC	P06493	CDK1	S64	R60Q	60	Missense	distal	-4	no	3.405	3.423	EPSD	TCGA;COSMIC	3.158	Up-regulation
CMGC_CDK_CDC2_CDK1_ST	Q9BTA9	WAC	P06493	CDK1	S346	S346F	346	Missense	central	0	yes	4.360	0.000	EPSD	TCGA;ICGC;COSMIC	3.158	Loss
CMGC_CDK_CDC2_CDK1_ST	Q9BTA9	WAC	P06493	CDK1	S346	A342V	342	Missense	distal	-4	no	4.360	4.266	EPSD	TCGA;ICGC;COSMIC	3.158	Down-regulation
CMGC_CDK_CDC2_CDK1_ST	Q9BTA9	WAC	P06493	CDK1	S346	S351L	351	Missense	distal	5	no	4.360	4.574	EPSD	TCGA;ICGC	3.158	Up-regulation
CMGC_CDK_CDC2_CDK1_ST	Q9BTA9	WAC	P06493	CDK1	S351	S346F	346	Missense	distal	-5	no	3.324	3.434	EPSD	TCGA;ICGC;COSMIC	3.158	Up-regulation
CMGC_CDK_CDC2_CDK1_ST	Q9BTA9	WAC	P06493	CDK1	S351	P355S	355	Missense	distal	4	no	3.324	3.321	EPSD	TCGA;COSMIC	3.158	Down-regulation
CMGC_CDK_CDC2_CDK1_ST	Q9BTA9	WAC	P06493	CDK1	S351	Q358R	358	Missense	distal	7	no	3.324	3.329	EPSD	TCGA;COSMIC	3.158	Up-regulation
CMGC_CDK_CDC2_CDK1_ST	Q9BTA9	WAC	P06493	CDK1	S351	S351L	351	Missense	central	0	yes	3.324	0.000	EPSD	TCGA;ICGC	3.158	Loss
CMGC_CDK_CDC2_CDK1_ST	Q9BTA9	WAC	P06493	CDK1	T471	P464S	464	Missense	distal	-7	no	3.127	3.167	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	3.158	Gain
CMGC_CDK_CDC2_CDK1_ST	Q9BTA9	WAC	P06493	CDK1	S548	A549P	549	Missense	proximal	1	no	2.279	3.168	EPSD	TCGA;ICGC;COSMIC	3.158	Gain
CMGC_CDK_CDC2_CDK1_ST	Q9BTA9	WAC	P06493	CDK1	T556	R550Q	550	Missense	distal	-6	no	3.210	3.209	EPSD	TCGA;ICGC;COSMIC	3.158	Down-regulation
CMGC_CDK_CDC2_CDK1_ST	Q9BTA9	WAC	P06493	CDK1	T556	A549P	549	Missense	distal	-7	no	3.210	3.143	EPSD	TCGA;ICGC;COSMIC	3.158	Loss
CMGC_CDK_CDC2_CDK1_ST	Q9BTA9	WAC	P06493	CDK1	T556	R550P	550	Missense	distal	-6	no	3.210	3.205	EPSD	TCGA;ICGC;COSMIC	3.158	Down-regulation
CMGC_CDK_CDC2_CDK1_ST	Q9BTA9	WAC	P06493	CDK1	T556	S551F	551	Missense	distal	-5	no	3.210	3.320	EPSD	TCGA;ICGC;COSMIC	3.158	Up-regulation
CMGC_CDK_CDC2_CDK1_ST	Q96PY5	FMNL2	P06493	CDK1	S1016	S1018F	1018	Missense	proximal	2	no	3.430	3.452	EPSD;PhosphoSitePlus	TCGA;COSMIC	3.158	Up-regulation
CMGC_CDK_CDC2_CDK1_ST	Q14157	UBAP2L	P06493	CDK1	S609	S608L	608	Missense	proximal	-1	no	3.119	3.321	EPSD	TCGA;ICGC;COSMIC	3.158	Gain
CMGC_CDK_CDC2_CDK1_ST	O75154	RAB11FIP3	P06493	CDK1	T562	N555S	555	Missense	distal	-7	no	3.161	3.221	EPSD	TCGA;COSMIC	3.158	Up-regulation
CMGC_CDK_CDC2_CDK1_ST	O75154	RAB11FIP3	P06493	CDK1	T562	P563S	563	Missense	proximal	1	no	3.161	-0.024	EPSD	TCGA;COSMIC	3.158	Loss
CMGC_CDK_CDC2_CDK1_ST	Q8NCD3	HJURP	P06493	CDK1	T380	V379M	379	Missense	proximal	-1	no	3.423	3.366	EPSD	TCGA;COSMIC	3.158	Down-regulation
CMGC_CDK_CDC2_CDK1_ST	Q8NCD3	HJURP	P06493	CDK1	T380	L387F	387	Missense	distal	7	no	3.423	3.415	EPSD	TCGA;COSMIC;CCLE	3.158	Down-regulation
CMGC_CDK_CDC2_CDK1_ST	Q8NCD3	HJURP	P06493	CDK1	S557	I551V	551	Missense	distal	-6	no	3.233	3.230	EPSD	TCGA	3.158	Down-regulation
CMGC_CDK_CDC2_CDK1_ST	P46013	MKI67	P06493	CDK1	S235	P236L	236	Missense	proximal	1	no	3.607	-0.079	EPSD	TCGA;ICGC;COSMIC	3.158	Loss
CMGC_CDK_CDC2_CDK1_ST	P46013	MKI67	P06493	CDK1	S235	P236S	236	Missense	proximal	1	no	3.607	0.422	EPSD	TCGA;ICGC;COSMIC	3.158	Loss
CMGC_CDK_CDC2_CDK1_ST	P46013	MKI67	P06493	CDK1	S235	F237S	237	Missense	proximal	2	no	3.607	3.585	EPSD	TCGA;ICGC	3.158	Down-regulation
CMGC_CDK_CDC2_CDK1_ST	P46013	MKI67	P06493	CDK1	T328	Q327K	327	Missense	proximal	-1	no	3.342	3.423	EPSD	TCGA;ICGC;COSMIC	3.158	Up-regulation
CMGC_CDK_CDC2_CDK1_ST	P46013	MKI67	P06493	CDK1	T328	V323L	323	Missense	distal	-5	no	3.342	3.369	EPSD	TCGA;ICGC;COSMIC	3.158	Up-regulation
CMGC_CDK_CDC2_CDK1_ST	P46013	MKI67	P06493	CDK1	T328	A335T	335	Missense	distal	7	no	3.342	3.356	EPSD	TCGA;ICGC;COSMIC	3.158	Up-regulation
CMGC_CDK_CDC2_CDK1_ST	P46013	MKI67	P06493	CDK1	T328	V333A	333	Missense	distal	5	no	3.342	3.135	EPSD	TCGA;ICGC;COSMIC	3.158	Loss
CMGC_CDK_CDC2_CDK1_ST	P46013	MKI67	P06493	CDK1	T347	E341G	341	Missense	distal	-6	no	3.547	3.561	EPSD	TCGA;ICGC;COSMIC	3.158	Up-regulation
CMGC_CDK_CDC2_CDK1_ST	P46013	MKI67	P06493	CDK1	T347	E341Q	341	Missense	distal	-6	no	3.547	3.543	EPSD	TCGA;ICGC;COSMIC	3.158	Down-regulation
CMGC_CDK_CDC2_CDK1_ST	P46013	MKI67	P06493	CDK1	T543	L539V	539	Missense	distal	-4	no	3.094	3.166	EPSD	TCGA;COSMIC	3.158	Gain
CMGC_CDK_CDC2_CDK1_ST	P46013	MKI67	P06493	CDK1	T543	S538Y	538	Missense	distal	-5	no	3.094	3.174	EPSD	TCGA;COSMIC	3.158	Gain
CMGC_CDK_CDC2_CDK1_ST	P46013	MKI67	P06493	CDK1	S1071	L1076P	1076	Missense	distal	5	no	3.302	3.117	EPSD	TCGA;COSMIC	3.158	Loss
CMGC_CDK_CDC2_CDK1_ST	P46013	MKI67	P06493	CDK1	S1071	E1070K	1070	Missense	proximal	-1	no	3.302	3.341	EPSD	TCGA	3.158	Up-regulation
CMGC_CDK_CDC2_CDK1_ST	P46013	MKI67	P06493	CDK1	S1071	P1072S	1072	Missense	proximal	1	no	3.302	0.117	EPSD	TCGA;COSMIC	3.158	Loss
CMGC_CDK_CDC2_CDK1_ST	P46013	MKI67	P06493	CDK1	S1071	K1073E	1073	Missense	proximal	2	no	3.302	3.307	EPSD	TCGA;COSMIC	3.158	Up-regulation
CMGC_CDK_CDC2_CDK1_ST	P46013	MKI67	P06493	CDK1	T1176	M1174I	1174	Missense	proximal	-2	no	4.400	4.476	EPSD	TCGA;COSMIC	3.158	Up-regulation
CMGC_CDK_CDC2_CDK1_ST	P46013	MKI67	P06493	CDK1	T1176	T1176M	1176	Missense	central	0	yes	4.400	0.000	EPSD	TCGA;COSMIC	3.158	Loss
CMGC_CDK_CDC2_CDK1_ST	P46013	MKI67	P06493	CDK1	T1176	G1181E	1181	Missense	distal	5	no	4.400	4.298	EPSD	TCGA;COSMIC	3.158	Down-regulation
CMGC_CDK_CDC2_CDK1_ST	P46013	MKI67	P06493	CDK1	T1298	A1295V	1295	Missense	distal	-3	no	4.246	4.184	EPSD	TCGA;COSMIC	3.158	Down-regulation
CMGC_CDK_CDC2_CDK1_ST	P46013	MKI67	P06493	CDK1	T1540	M1538V	1538	Missense	proximal	-2	no	4.189	4.217	EPSD	TCGA	3.158	Up-regulation
CMGC_CDK_CDC2_CDK1_ST	P46013	MKI67	P06493	CDK1	T1540	V1545I	1545	Missense	distal	5	no	4.189	4.203	EPSD	TCGA;COSMIC	3.158	Up-regulation
CMGC_CDK_CDC2_CDK1_ST	P46013	MKI67	P06493	CDK1	T1540	A1534V	1534	Missense	distal	-6	no	4.189	4.210	EPSD	TCGA;COSMIC	3.158	Up-regulation
CMGC_CDK_CDC2_CDK1_ST	P46013	MKI67	P06493	CDK1	T1540	H1539R	1539	Missense	proximal	-1	no	4.189	4.166	EPSD	TCGA;COSMIC	3.158	Down-regulation
CMGC_CDK_CDC2_CDK1_ST	P46013	MKI67	P06493	CDK1	T1784	T1784A	1784	Missense	central	0	yes	3.745	0.000	EPSD	TCGA;COSMIC	3.158	Loss
CMGC_CDK_CDC2_CDK1_ST	P46013	MKI67	P06493	CDK1	T1784	T1784I	1784	Missense	central	0	yes	3.745	0.000	EPSD	TCGA;COSMIC	3.158	Loss
CMGC_CDK_CDC2_CDK1_ST	P46013	MKI67	P06493	CDK1	T1784	G1779V	1779	Missense	distal	-5	no	3.745	3.736	EPSD	TCGA;COSMIC	3.158	Down-regulation
CMGC_CDK_CDC2_CDK1_ST	P46013	MKI67	P06493	CDK1	T1848	T1849P	1849	Missense	proximal	1	no	0.830	3.263	EPSD	TCGA;COSMIC	3.158	Gain
CMGC_CDK_CDC2_CDK1_ST	P46013	MKI67	P06493	CDK1	T1897	F1890C	1890	Missense	distal	-7	no	3.128	3.160	EPSD	TCGA;COSMIC	3.158	Gain
CMGC_CDK_CDC2_CDK1_ST	P46013	MKI67	P06493	CDK1	T1923	V1925M	1925	Missense	proximal	2	no	3.161	3.153	EPSD	TCGA	3.158	Loss
CMGC_CDK_CDC2_CDK1_ST	P46013	MKI67	P06493	CDK1	T1923	F1920S	1920	Missense	distal	-3	no	3.161	3.188	EPSD	TCGA	3.158	Up-regulation
CMGC_CDK_CDC2_CDK1_ST	P46013	MKI67	P06493	CDK1	T1923	D1916Y	1916	Missense	distal	-7	no	3.161	3.107	EPSD	TCGA;COSMIC	3.158	Loss
CMGC_CDK_CDC2_CDK1_ST	P46013	MKI67	P06493	CDK1	S1983	P1986A	1986	Missense	distal	3	no	3.059	3.162	EPSD	TCGA;COSMIC	3.158	Gain
CMGC_CDK_CDC2_CDK1_ST	P46013	MKI67	P06493	CDK1	S1983	I1976S	1976	Missense	distal	-7	no	3.059	3.211	EPSD	TCGA;COSMIC	3.158	Gain
CMGC_CDK_CDC2_CDK1_ST	P46013	MKI67	P06493	CDK1	S2223	R2222I	2222	Missense	proximal	-1	no	3.306	3.443	EPSD	TCGA;COSMIC	3.158	Up-regulation
CMGC_CDK_CDC2_CDK1_ST	P46013	MKI67	P06493	CDK1	T2268	G2263W	2263	Missense	distal	-5	no	3.903	3.860	EPSD	TCGA;COSMIC	3.158	Down-regulation
CMGC_CDK_CDC2_CDK1_ST	P46013	MKI67	P06493	CDK1	T2268	S2261L	2261	Missense	distal	-7	no	3.903	3.702	EPSD	TCGA;COSMIC	3.158	Down-regulation
CMGC_CDK_CDC2_CDK1_ST	P46013	MKI67	P06493	CDK1	T2268	A2265V	2265	Missense	distal	-3	no	3.903	3.842	EPSD	TCGA	3.158	Down-regulation
CMGC_CDK_CDC2_CDK1_ST	P46013	MKI67	P06493	CDK1	T2352	R2359W	2359	Missense	distal	7	no	3.281	3.288	EPSD	TCGA;COSMIC	3.158	Up-regulation
CMGC_CDK_CDC2_CDK1_ST	P46013	MKI67	P06493	CDK1	T2352	K2357N	2357	Missense	distal	5	no	3.281	3.289	EPSD	TCGA	3.158	Up-regulation
CMGC_CDK_CDC2_CDK1_ST	P46013	MKI67	P06493	CDK1	T2389	G2384D	2384	Missense	distal	-5	no	4.050	3.968	EPSD	TCGA;COSMIC	3.158	Down-regulation
CMGC_CDK_CDC2_CDK1_ST	P46013	MKI67	P06493	CDK1	T2389	G2384V	2384	Missense	distal	-5	no	4.050	4.041	EPSD	TCGA;COSMIC	3.158	Down-regulation
CMGC_CDK_CDC2_CDK1_ST	P46013	MKI67	P06493	CDK1	S2528	F2525C	2525	Missense	distal	-3	no	3.238	3.250	EPSD	TCGA;COSMIC	3.158	Up-regulation
CMGC_CDK_CDC2_CDK1_ST	P46013	MKI67	P06493	CDK1	S2528	K2523N	2523	Missense	distal	-5	no	3.238	3.202	EPSD	TCGA;COSMIC	3.158	Down-regulation
CMGC_CDK_CDC2_CDK1_ST	Q5BJF6	ODF2	P06493	CDK1	T92	H87Y	87	Missense	distal	-5	no	3.375	3.403	EPSD	TCGA;COSMIC	3.158	Up-regulation
CMGC_CDK_CDC2_CDK1_ST	Q14005	IL16	P06493	CDK1	T757	A764T	764	Missense	distal	7	no	3.184	3.198	PhosphoSitePlus	TCGA;COSMIC	3.158	Up-regulation
CMGC_CDK_CDC2_CDK1_ST	Q14005	IL16	P06493	CDK1	T757	D762N	762	Missense	distal	5	no	3.184	3.136	PhosphoSitePlus	TCGA;COSMIC	3.158	Loss
CMGC_CDK_CDC2_CDK1_ST	Q14005	IL16	P06493	CDK1	T757	P758S	758	Missense	proximal	1	no	3.184	0.000	PhosphoSitePlus	TCGA	3.158	Loss
CMGC_CDK_CDC2_CDK1_ST	Q14005	IL16	P06493	CDK1	S1023	E1030K	1030	Missense	distal	7	no	3.239	3.235	EPSD	TCGA;COSMIC;GDSC;CCLE	3.158	Down-regulation
CMGC_CDK_CDC2_CDK1_ST	Q9UQR0	SCML2	P06493	CDK1	S499	T503P	503	Missense	distal	4	no	3.333	3.329	EPSD	TCGA;ICGC	3.158	Down-regulation
CMGC_CDK_CDC2_CDK1_ST	Q9UQR0	SCML2	P06493	CDK1	S499	R498L	498	Missense	proximal	-1	no	3.333	3.472	EPSD	TCGA;ICGC;COSMIC	3.158	Up-regulation
CMGC_CDK_CDC2_CDK1_ST	Q9UQR0	SCML2	P06493	CDK1	S590	H596L	596	Missense	distal	6	no	3.218	3.167	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	3.158	Down-regulation
CMGC_CDK_CDC2_CDK1_ST	Q9UQR0	SCML2	P06493	CDK1	S590	V586F	586	Missense	distal	-4	no	3.218	3.193	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	3.158	Down-regulation
CMGC_CDK_CDC2_CDK1_ST	P00533	EGFR	P06493	CDK1	T693	P699L	699	Missense	distal	6	no	3.602	3.546	EPSD	TCGA;COSMIC	3.158	Down-regulation
CMGC_CDK_CDC2_CDK1_ST	Q99708	RBBP8	P06493	CDK1	S10	S13C	13	Missense	distal	3	no	3.676	3.627	EPSD	TCGA;ICGC;COSMIC	3.158	Down-regulation
CMGC_CDK_CDC2_CDK1_ST	Q99708	RBBP8	P06493	CDK1	S10	N12K	12	Missense	proximal	2	no	3.676	3.675	EPSD	TCGA;ICGC;COSMIC	3.158	Down-regulation
CMGC_CDK_CDC2_CDK1_ST	Q99708	RBBP8	P06493	CDK1	S10	A14V	14	Missense	distal	4	no	3.676	3.540	EPSD	TCGA;ICGC;COSMIC	3.158	Down-regulation
CMGC_CDK_CDC2_CDK1_ST	Q99708	RBBP8	P06493	CDK1	T245	P246L	246	Missense	proximal	1	no	3.549	-0.138	EPSD	TCGA;ICGC;COSMIC	3.158	Loss
CMGC_CDK_CDC2_CDK1_ST	Q99708	RBBP8	P06493	CDK1	S327	A332T	332	Missense	distal	5	no	3.110	3.174	PhosphoSitePlus	TCGA;ICGC;COSMIC	3.158	Gain
CMGC_CDK_CDC2_CDK1_ST	Q99708	RBBP8	P06493	CDK1	S568	P569T	569	Missense	proximal	1	no	3.390	0.957	EPSD	TCGA;ICGC;COSMIC	3.158	Loss
CMGC_CDK_CDC2_CDK1_ST	Q99708	RBBP8	P06493	CDK1	S568	C567W	567	Missense	proximal	-1	no	3.390	3.407	EPSD	TCGA;ICGC;COSMIC	3.158	Up-regulation
CMGC_CDK_CDC2_CDK1_ST	Q99708	RBBP8	P06493	CDK1	S889	K893N	893	Missense	distal	4	no	3.699	3.695	EPSD	TCGA;ICGC;COSMIC	3.158	Down-regulation
CMGC_CDK_CDC2_CDK1_ST	Q99708	RBBP8	P06493	CDK1	S889	K896T	896	Missense	distal	7	no	3.699	3.693	EPSD	TCGA;ICGC;COSMIC	3.158	Down-regulation
CMGC_CDK_CDC2_CDK1_ST	Q16513	PKN2	P06493	CDK1	T958	R961Q	961	Missense	distal	3	no	3.476	3.427	EPSD	TCGA;COSMIC	3.158	Down-regulation
CMGC_CDK_CDC2_CDK1_ST	O00562	PITPNM1	P06493	CDK1	S382	T389A	389	Missense	distal	7	no	3.280	3.266	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	3.158	Down-regulation
CMGC_CDK_CDC2_CDK1_ST	O00562	PITPNM1	P06493	CDK1	S382	F376L	376	Missense	distal	-6	no	3.280	3.284	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	3.158	Up-regulation
CMGC_CDK_CDC2_CDK1_ST	O00562	PITPNM1	P06493	CDK1	T389	P392S	392	Missense	distal	3	no	3.279	3.329	EPSD	TCGA;ICGC;COSMIC;GDSC;CCLE	3.158	Up-regulation
CMGC_CDK_CDC2_CDK1_ST	O00562	PITPNM1	P06493	CDK1	T389	T389A	389	Missense	central	0	yes	3.279	0.000	EPSD	TCGA;ICGC;COSMIC	3.158	Loss
CMGC_CDK_CDC2_CDK1_ST	O00562	PITPNM1	P06493	CDK1	T389	P392H	392	Missense	distal	3	no	3.279	3.307	EPSD	TCGA;ICGC	3.158	Up-regulation
CMGC_CDK_CDC2_CDK1_ST	O00562	PITPNM1	P06493	CDK1	S896	K903R	903	Missense	distal	7	no	3.383	3.382	EPSD	TCGA	3.158	Down-regulation
CMGC_CDK_CDC2_CDK1_ST	O00562	PITPNM1	P06493	CDK1	S896	E890D	890	Missense	distal	-6	no	3.383	3.384	EPSD	TCGA;COSMIC	3.158	Up-regulation
CMGC_CDK_CDC2_CDK1_ST	O00562	PITPNM1	P06493	CDK1	S896	P897L	897	Missense	proximal	1	no	3.383	-0.303	EPSD	TCGA;COSMIC	3.158	Loss
CMGC_CDK_CDC2_CDK1_ST	O00562	PITPNM1	P06493	CDK1	T1223	A1216V	1216	Missense	distal	-7	no	3.225	3.073	EPSD	TCGA;COSMIC	3.158	Loss
CMGC_CDK_CDC2_CDK1_ST	O00562	PITPNM1	P06493	CDK1	T1223	R1230W	1230	Missense	distal	7	no	3.225	3.233	EPSD	TCGA;COSMIC	3.158	Up-regulation
CMGC_CDK_CDC2_CDK1_ST	O00562	PITPNM1	P06493	CDK1	T1223	P1221A	1221	Missense	proximal	-2	no	3.225	3.232	EPSD	TCGA;COSMIC	3.158	Up-regulation
CMGC_CDK_CDC2_CDK1_ST	O00562	PITPNM1	P06493	CDK1	T1223	E1219K	1219	Missense	distal	-4	no	3.225	3.171	EPSD	TCGA;COSMIC	3.158	Down-regulation
CMGC_CDK_CDC2_CDK1_ST	O00562	PITPNM1	P06493	CDK1	T1223	R1218C	1218	Missense	distal	-5	no	3.225	3.258	EPSD	TCGA;COSMIC	3.158	Up-regulation
CMGC_CDK_CDC2_CDK1_ST	Q9Y2V2	CARHSP1	P06493	CDK1	T23	R25W	25	Missense	proximal	2	no	3.319	3.326	PhosphoSitePlus	TCGA;ICGC;COSMIC	3.158	Up-regulation
CMGC_CDK_CDC2_CDK1_ST	Q9Y2V2	CARHSP1	P06493	CDK1	T23	R27C	27	Missense	distal	4	no	3.319	3.255	PhosphoSitePlus	TCGA;ICGC;COSMIC	3.158	Down-regulation
CMGC_CDK_CDC2_CDK1_ST	Q9Y2V2	CARHSP1	P06493	CDK1	T23	R29H	29	Missense	distal	6	no	3.319	3.300	PhosphoSitePlus	TCGA;ICGC	3.158	Down-regulation
CMGC_CDK_CDC2_CDK1_ST	O00429	DNM1L	P06493	CDK1	T394	I396S	396	Missense	proximal	2	no	3.433	3.412	EPSD	TCGA;COSMIC	3.158	Down-regulation
CMGC_CDK_CDC2_CDK1_ST	P08670	VIM	P06493	CDK1	S420	L421P	421	Missense	proximal	1	no	-0.244	3.442	EPSD	TCGA;ICGC;COSMIC	3.158	Gain
CMGC_CDK_CDC2_CDK1_ST	O00512	BCL9	P06493	CDK1	S62	C64F	64	Missense	proximal	2	no	3.412	3.421	EPSD	TCGA;ICGC;COSMIC	3.158	Up-regulation
CMGC_CDK_CDC2_CDK1_ST	O00512	BCL9	P06493	CDK1	S62	S59F	59	Missense	distal	-3	no	3.412	3.385	EPSD	TCGA;ICGC;COSMIC	3.158	Down-regulation
CMGC_CDK_CDC2_CDK1_ST	O00512	BCL9	P06493	CDK1	T172	V179M	179	Missense	distal	7	no	3.232	3.220	PhosphoSitePlus	TCGA;ICGC;COSMIC	3.158	Down-regulation
CMGC_CDK_CDC2_CDK1_ST	O00512	BCL9	P06493	CDK1	T172	K171R	171	Missense	proximal	-1	no	3.232	3.162	PhosphoSitePlus	TCGA;ICGC;COSMIC	3.158	Down-regulation
CMGC_CDK_CDC2_CDK1_ST	O00512	BCL9	P06493	CDK1	T172	V176A	176	Missense	distal	4	no	3.232	3.368	PhosphoSitePlus	TCGA;ICGC;COSMIC	3.158	Up-regulation
CMGC_CDK_CDC2_CDK1_ST	O00512	BCL9	P06493	CDK1	T172	A174V	174	Missense	proximal	2	no	3.232	3.255	PhosphoSitePlus	TCGA;ICGC;COSMIC	3.158	Up-regulation
CMGC_CDK_CDC2_CDK1_ST	O00512	BCL9	P06493	CDK1	T172	Q170H	170	Missense	proximal	-2	no	3.232	3.240	PhosphoSitePlus	TCGA;ICGC	3.158	Up-regulation
CMGC_CDK_CDC2_CDK1_ST	O00512	BCL9	P06493	CDK1	S441	P447S	447	Missense	distal	6	no	3.178	3.186	EPSD	TCGA;ICGC;COSMIC	3.158	Up-regulation
CMGC_CDK_CDC2_CDK1_ST	O00512	BCL9	P06493	CDK1	S441	V438I	438	Missense	distal	-3	no	3.178	3.157	EPSD	TCGA;ICGC;COSMIC	3.158	Loss
CMGC_CDK_CDC2_CDK1_ST	O00512	BCL9	P06493	CDK1	S441	P442T	442	Missense	proximal	1	no	3.178	0.745	EPSD	TCGA;ICGC;COSMIC	3.158	Loss
CMGC_CDK_CDC2_CDK1_ST	O00512	BCL9	P06493	CDK1	S1335	T1340I	1340	Missense	distal	5	no	3.032	3.190	EPSD	TCGA;ICGC;COSMIC	3.158	Gain
CMGC_CDK_CDC2_CDK1_ST	Q9H410	DSN1	P06493	CDK1	S30	H23Y	23	Missense	distal	-7	no	3.403	3.349	EPSD	TCGA;ICGC;COSMIC	3.158	Down-regulation
CMGC_CDK_CDC2_CDK1_ST	O00311	CDC7	P06493	CDK1	S16	F22S	22	Missense	distal	6	no	3.390	3.441	EPSD	TCGA;ICGC	3.158	Up-regulation
CMGC_CDK_CDC2_CDK1_ST	O00311	CDC7	P06493	CDK1	S302	S297F	297	Missense	distal	-5	no	3.061	3.171	EPSD	TCGA;COSMIC	3.158	Gain
CMGC_CDK_CDC2_CDK1_ST	O14773	TPP1	P06493	CDK1	T478	G473R	473	Missense	distal	-5	no	3.315	3.247	EPSD	TCGA;ICGC;COSMIC	3.158	Down-regulation
CMGC_CDK_CDC2_CDK1_ST	Q8IZP0	ABI1	P06493	CDK1	T196	P197H	197	Missense	proximal	1	no	3.597	0.912	EPSD	TCGA;COSMIC	3.158	Loss
CMGC_CDK_CDC2_CDK1_ST	P16949	STMN1	P06493	CDK1	S25	S31Y	31	Missense	distal	6	no	3.749	3.710	PhosphoSitePlus;EPSD	TCGA;COSMIC	3.158	Down-regulation
CMGC_CDK_CDC2_CDK1_ST	P16949	STMN1	P06493	CDK1	S25	S28P	28	Missense	distal	3	no	3.749	3.699	PhosphoSitePlus;EPSD	TCGA;ICGC	3.158	Down-regulation
CMGC_CDK_CDC2_CDK1_ST	P16949	STMN1	P06493	CDK1	S25	K29I	29	Missense	distal	4	no	3.749	3.667	PhosphoSitePlus;EPSD	TCGA;ICGC;COSMIC	3.158	Down-regulation
CMGC_CDK_CDC2_CDK1_ST	P16949	STMN1	P06493	CDK1	S38	S31Y	31	Missense	distal	-7	no	3.443	3.328	EPSD;PhosphoSitePlus	TCGA;COSMIC	3.158	Down-regulation
CMGC_CDK_CDC2_CDK1_ST	P16949	STMN1	P06493	CDK1	S38	P39S	39	Missense	proximal	1	no	3.443	0.259	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	3.158	Loss
CMGC_CDK_CDC2_CDK1_ST	P11387	TOP1	P06493	CDK1	S394	P393S	393	Missense	proximal	-1	no	3.284	3.232	PhosphoSitePlus;EPSD	TCGA;ICGC;COSMIC	3.158	Down-regulation
CMGC_CDK_CDC2_CDK1_ST	P11387	TOP1	P06493	CDK1	S394	P397S	397	Missense	distal	3	no	3.284	3.334	PhosphoSitePlus;EPSD	TCGA;ICGC;COSMIC	3.158	Up-regulation
CMGC_CDK_CDC2_CDK1_ST	P78344	EIF4G2	P06493	CDK1	T89	L96P	96	Missense	distal	7	no	3.991	3.963	EPSD	TCGA;ICGC;COSMIC	3.158	Down-regulation
CMGC_CDK_CDC2_CDK1_ST	P78344	EIF4G2	P06493	CDK1	T89	R82T	82	Missense	distal	-7	no	3.991	4.047	EPSD	TCGA;ICGC;COSMIC	3.158	Up-regulation
CMGC_CDK_CDC2_CDK1_ST	P06400	RB1	P06493	CDK1	T356	S350I	350	Missense	distal	-6	no	3.378	3.401	EPSD	TCGA;ICGC;COSMIC;GDSC	3.158	Up-regulation
CMGC_CDK_CDC2_CDK1_ST	P06400	RB1	P06493	CDK1	S780	I782M	782	Missense	proximal	2	no	3.910	3.897	EPSD	TCGA;ICGC;COSMIC	3.158	Down-regulation
CMGC_CDK_CDC2_CDK1_ST	P06400	RB1	P06493	CDK1	S780	R787Q	787	Missense	distal	7	no	3.910	3.905	EPSD	TCGA;ICGC;COSMIC	3.158	Down-regulation
CMGC_CDK_CDC2_CDK1_ST	P06400	RB1	P06493	CDK1	S807	N803S	803	Missense	distal	-4	no	3.756	3.829	EPSD;PhosphoSitePlus	TCGA;ICGC	3.158	Up-regulation
CMGC_CDK_CDC2_CDK1_ST	Q8WWK9	CKAP2	P06493	CDK1	S357	A358P	358	Missense	proximal	1	no	2.331	3.220	EPSD	TCGA;COSMIC	3.158	Gain
CMGC_CDK_CDC2_CDK1_ST	Q8WWK9	CKAP2	P06493	CDK1	T579	P573A	573	Missense	distal	-6	no	3.271	3.268	EPSD	TCGA;COSMIC	3.158	Down-regulation
CMGC_CDK_CDC2_CDK1_ST	Q8WWK9	CKAP2	P06493	CDK1	T579	E583K	583	Missense	distal	4	no	3.271	3.302	EPSD	TCGA;COSMIC	3.158	Up-regulation
CMGC_CDK_CDC2_CDK1_ST	Q8WWK9	CKAP2	P06493	CDK1	T579	T584M	584	Missense	distal	5	no	3.271	3.334	EPSD	TCGA;COSMIC	3.158	Up-regulation
CMGC_CDK_CDC2_CDK1_ST	Q8WWK9	CKAP2	P06493	CDK1	T579	T584A	584	Missense	distal	5	no	3.271	3.208	EPSD	TCGA;COSMIC	3.158	Down-regulation
CMGC_CDK_CDC2_CDK1_ST	Q69YH5	CDCA2	P06493	CDK1	T68	Q64R	64	Missense	distal	-4	no	3.243	3.225	EPSD	TCGA;ICGC;COSMIC	3.158	Down-regulation
CMGC_CDK_CDC2_CDK1_ST	Q69YH5	CDCA2	P06493	CDK1	T68	E70G	70	Missense	proximal	2	no	3.243	3.256	EPSD	TCGA;ICGC;COSMIC	3.158	Up-regulation
CMGC_CDK_CDC2_CDK1_ST	Q69YH5	CDCA2	P06493	CDK1	S120	S126Y	126	Missense	distal	6	no	3.204	3.166	EPSD	TCGA;ICGC;COSMIC	3.158	Down-regulation
CMGC_CDK_CDC2_CDK1_ST	Q69YH5	CDCA2	P06493	CDK1	T321	R328C	328	Missense	distal	7	no	3.165	3.171	EPSD	TCGA;ICGC;COSMIC	3.158	Up-regulation
CMGC_CDK_CDC2_CDK1_ST	Q69YH5	CDCA2	P06493	CDK1	T412	S407Y	407	Missense	distal	-5	no	3.839	3.920	PhosphoSitePlus	TCGA;ICGC;COSMIC	3.158	Up-regulation
CMGC_CDK_CDC2_CDK1_ST	Q69YH5	CDCA2	P06493	CDK1	T412	K416I	416	Missense	distal	4	no	3.839	3.758	PhosphoSitePlus	TCGA;ICGC;COSMIC	3.158	Down-regulation
CMGC_CDK_CDC2_CDK1_ST	Q69YH5	CDCA2	P06493	CDK1	S437	S431F	431	Missense	distal	-6	no	3.507	3.531	EPSD	TCGA;ICGC;COSMIC	3.158	Up-regulation
CMGC_CDK_CDC2_CDK1_ST	Q69YH5	CDCA2	P06493	CDK1	S591	E598Q	598	Missense	distal	7	no	3.716	3.706	EPSD	TCGA;ICGC;COSMIC	3.158	Down-regulation
CMGC_CDK_CDC2_CDK1_ST	Q69YH5	CDCA2	P06493	CDK1	S756	D758Y	758	Missense	proximal	2	no	3.415	3.421	EPSD	TCGA;ICGC	3.158	Up-regulation
CMGC_CDK_CDC2_CDK1_ST	P04179	SOD2	P06493	CDK1	S106	G110D	110	Missense	distal	4	no	3.273	3.336	PhosphoSitePlus	TCGA;COSMIC	3.158	Up-regulation
CMGC_CDK_CDC2_CDK1_ST	Q14247	CTTN	P06493	CDK1	S113	Q114P	114	Missense	proximal	1	no	1.245	3.668	EPSD	TCGA;ICGC;COSMIC	3.158	Gain
CMGC_CDK_CDC2_CDK1_ST	O95251	KAT7	P06493	CDK1	S57	S56F	56	Missense	proximal	-1	no	3.123	3.276	EPSD	TCGA;ICGC;COSMIC	3.158	Gain
CMGC_CDK_CDC2_CDK1_ST	O95251	KAT7	P06493	CDK1	S57	S52I	52	Missense	distal	-5	no	3.123	3.253	EPSD	TCGA;ICGC;COSMIC	3.158	Gain
CMGC_CDK_CDC2_CDK1_ST	O95251	KAT7	P06493	CDK1	T187	F181L	181	Missense	distal	-6	no	3.333	3.337	EPSD	TCGA;ICGC;COSMIC	3.158	Up-regulation
CMGC_CDK_CDC2_CDK1_ST	O95251	KAT7	P06493	CDK1	S506	R509C	509	Missense	distal	3	no	4.232	4.112	EPSD	TCGA;COSMIC	3.158	Down-regulation
CMGC_CDK_CDC2_CDK1_ST	O95251	KAT7	P06493	CDK1	S506	S512L	512	Missense	distal	6	no	4.232	4.168	EPSD	TCGA;COSMIC	3.158	Down-regulation
CMGC_CDK_CDC2_CDK1_ST	O95251	KAT7	P06493	CDK1	S506	K503N	503	Missense	distal	-3	no	4.232	4.252	EPSD	TCGA;COSMIC	3.158	Up-regulation
CMGC_CDK_CDC2_CDK1_ST	Q96JH7	VCPIP1	P06493	CDK1	S1132	R1139S	1139	Missense	distal	7	no	3.488	3.480	EPSD	TCGA;ICGC;COSMIC	3.158	Down-regulation
CMGC_CDK_CDC2_CDK1_ST	Q9H4X1	RGCC	P06493	CDK1	T111	L106H	106	Missense	distal	-5	no	3.896	3.805	PhosphoSitePlus	TCGA;ICGC;COSMIC	3.158	Down-regulation
CMGC_CDK_CDC2_CDK1_ST	Q6PGQ7	BORA	P06493	CDK1	T52	R57T	57	Missense	distal	5	no	3.142	3.158	EPSD	TCGA;ICGC	3.158	Gain
CMGC_CDK_CDC2_CDK1_ST	Q6PGQ7	BORA	P06493	CDK1	S233	S229L	229	Missense	distal	-4	no	3.564	3.370	EPSD	TCGA;ICGC	3.158	Down-regulation
CMGC_CDK_CDC2_CDK1_ST	Q6PGQ7	BORA	P06493	CDK1	S233	D231Y	231	Missense	proximal	-2	no	3.564	3.596	EPSD	TCGA;ICGC	3.158	Up-regulation
CMGC_CDK_CDC2_CDK1_ST	Q6PGQ7	BORA	P06493	CDK1	S252	S257T	257	Missense	distal	5	no	3.157	3.163	EPSD;PhosphoSitePlus	TCGA;ICGC	3.158	Gain
CMGC_CDK_CDC2_CDK1_ST	Q6PGQ7	BORA	P06493	CDK1	S252	S246L	246	Missense	distal	-6	no	3.157	3.185	EPSD;PhosphoSitePlus	TCGA;ICGC	3.158	Gain
CMGC_CDK_CDC2_CDK1_ST	Q6PGQ7	BORA	P06493	CDK1	S268	I272V	272	Missense	distal	4	no	3.196	3.216	EPSD	TCGA;ICGC	3.158	Up-regulation
CMGC_CDK_CDC2_CDK1_ST	Q6PGQ7	BORA	P06493	CDK1	S274	I272V	272	Missense	proximal	-2	no	3.375	3.326	EPSD	TCGA;ICGC	3.158	Down-regulation
CMGC_CDK_CDC2_CDK1_ST	Q6PGQ7	BORA	P06493	CDK1	S274	I280T	280	Missense	distal	6	no	3.375	3.426	EPSD	TCGA;ICGC	3.158	Up-regulation
CMGC_CDK_CDC2_CDK1_ST	Q6PGQ7	BORA	P06493	CDK1	S299	K294T	294	Missense	distal	-5	no	3.704	3.618	EPSD	TCGA;ICGC	3.158	Down-regulation
CMGC_CDK_CDC2_CDK1_ST	Q6PGQ7	BORA	P06493	CDK1	S325	P326S	326	Missense	proximal	1	no	3.394	0.210	EPSD	TCGA;ICGC	3.158	Loss
CMGC_CDK_CDC2_CDK1_ST	Q96EB6	SIRT1	P06493	CDK1	S540	R543I	543	Missense	distal	3	no	3.799	3.632	EPSD;PhosphoSitePlus	TCGA;COSMIC	3.158	Down-regulation
CMGC_CDK_CDC2_CDK1_ST	Q96EB6	SIRT1	P06493	CDK1	S682	Q681H	681	Missense	proximal	-1	no	3.276	3.311	EPSD	TCGA;COSMIC	3.158	Up-regulation
CMGC_CDK_CDC2_CDK1_ST	Q96EB6	SIRT1	P06493	CDK1	S682	S675N	675	Missense	distal	-7	no	3.276	3.217	EPSD	TCGA;COSMIC	3.158	Down-regulation
CMGC_CDK_CDC2_CDK1_ST	P13639	EEF2	P06493	CDK1	S360	L358V	358	Missense	proximal	-2	no	3.418	3.417	EPSD	TCGA;ICGC;COSMIC	3.158	Down-regulation
CMGC_CDK_CDC2_CDK1_ST	P13639	EEF2	P06493	CDK1	T735	A736T	736	Missense	proximal	1	no	3.177	1.632	EPSD	TCGA;ICGC;COSMIC	3.158	Loss
CMGC_CDK_CDC2_CDK1_ST	Q9UJX2	CDC23	P06493	CDK1	T562	P568R	568	Missense	distal	6	no	3.187	3.200	PhosphoSitePlus;EPSD	TCGA;ICGC;COSMIC	3.158	Up-regulation
CMGC_CDK_CDC2_CDK1_ST	Q9UJX2	CDC23	P06493	CDK1	T562	R557Q	557	Missense	distal	-5	no	3.187	3.154	PhosphoSitePlus;EPSD	TCGA;ICGC;GDSC;CCLE	3.158	Loss
CMGC_CDK_CDC2_CDK1_ST	Q9UJX2	CDC23	P06493	CDK1	T562	E561K	561	Missense	proximal	-1	no	3.187	3.225	PhosphoSitePlus;EPSD	TCGA;ICGC;COSMIC	3.158	Up-regulation
CMGC_CDK_CDC2_CDK1_ST	Q9UJX2	CDC23	P06493	CDK1	T596	V595A	595	Missense	proximal	-1	no	3.231	3.031	EPSD	TCGA;ICGC;COSMIC	3.158	Loss
CMGC_CDK_CDC2_CDK1_ST	Q13535	ATR	P06493	CDK1	S428	R432C	432	Missense	distal	4	no	3.175	3.111	PhosphoSitePlus	TCGA;COSMIC	3.158	Loss
CMGC_CDK_CDC2_CDK1_ST	Q13535	ATR	P06493	CDK1	S428	G426R	426	Missense	proximal	-2	no	3.175	3.153	PhosphoSitePlus	TCGA;ICGC;COSMIC	3.158	Loss
CMGC_CDK_CDC2_CDK1_ST	Q13535	ATR	P06493	CDK1	S428	P429L	429	Missense	proximal	1	no	3.175	-0.511	PhosphoSitePlus	TCGA;ICGC;COSMIC	3.158	Loss
CMGC_CDK_CDC2_CDK1_ST	Q13535	ATR	P06493	CDK1	S428	R433H	433	Missense	distal	5	no	3.175	3.240	PhosphoSitePlus	TCGA;ICGC;COSMIC	3.158	Up-regulation
CMGC_CDK_CDC2_CDK1_ST	Q13535	ATR	P06493	CDK1	S1007	D1001Y	1001	Missense	distal	-6	no	3.895	3.902	EPSD	TCGA;COSMIC	3.158	Up-regulation
CMGC_CDK_CDC2_CDK1_ST	Q13535	ATR	P06493	CDK1	S1007	L1013V	1013	Missense	distal	6	no	3.895	3.921	EPSD	TCGA;COSMIC	3.158	Up-regulation
CMGC_CDK_CDC2_CDK1_ST	Q13535	ATR	P06493	CDK1	S1693	S1693I	1693	Missense	central	0	yes	3.202	0.000	EPSD	TCGA;ICGC;COSMIC	3.158	Loss
CMGC_CDK_CDC2_CDK1_ST	Q13535	ATR	P06493	CDK1	S1693	D1687H	1687	Missense	distal	-6	no	3.202	3.204	EPSD	TCGA;ICGC;COSMIC	3.158	Up-regulation
CMGC_CDK_CDC2_CDK1_ST	Q13535	ATR	P06493	CDK1	S1693	G1691R	1691	Missense	proximal	-2	no	3.202	3.180	EPSD	TCGA;COSMIC	3.158	Down-regulation
CMGC_CDK_CDC2_CDK1_ST	Q13535	ATR	P06493	CDK1	S1693	E1699A	1699	Missense	distal	6	no	3.202	3.234	EPSD	TCGA;ICGC;COSMIC	3.158	Up-regulation
CMGC_CDK_CDC2_CDK1_ST	Q13535	ATR	P06493	CDK1	T1989	P1985S	1985	Missense	distal	-4	no	3.220	3.271	EPSD	TCGA;ICGC;COSMIC	3.158	Up-regulation
CMGC_CDK_CDC2_CDK1_ST	Q9ULW0	TPX2	P06493	CDK1	T113	A115T	115	Missense	proximal	2	no	3.322	3.328	EPSD	TCGA;ICGC;COSMIC	3.158	Up-regulation
CMGC_CDK_CDC2_CDK1_ST	Q9ULW0	TPX2	P06493	CDK1	T147	A146P	146	Missense	proximal	-1	no	3.081	3.186	EPSD	TCGA;ICGC;COSMIC	3.158	Gain
CMGC_CDK_CDC2_CDK1_ST	Q9ULW0	TPX2	P06493	CDK1	S186	A184T	184	Missense	proximal	-2	no	3.208	3.288	EPSD	TCGA;ICGC;COSMIC	3.158	Up-regulation
CMGC_CDK_CDC2_CDK1_ST	Q9ULW0	TPX2	P06493	CDK1	S293	R288Q	288	Missense	distal	-5	no	3.213	3.181	EPSD	TCGA;ICGC;COSMIC	3.158	Down-regulation
CMGC_CDK_CDC2_CDK1_ST	Q9ULW0	TPX2	P06493	CDK1	S293	R288L	288	Missense	distal	-5	no	3.213	3.299	EPSD	TCGA;ICGC;COSMIC	3.158	Up-regulation
CMGC_CDK_CDC2_CDK1_ST	Q9ULW0	TPX2	P06493	CDK1	S293	P294H	294	Missense	proximal	1	no	3.213	0.529	EPSD	TCGA;ICGC	3.158	Loss
CMGC_CDK_CDC2_CDK1_ST	Q9ULW0	TPX2	P06493	CDK1	S293	G300V	300	Missense	distal	7	no	3.213	3.210	EPSD	TCGA;ICGC;COSMIC	3.158	Down-regulation
CMGC_CDK_CDC2_CDK1_ST	Q9ULW0	TPX2	P06493	CDK1	S293	P291L	291	Missense	proximal	-2	no	3.213	3.387	EPSD	TCGA;ICGC;COSMIC	3.158	Up-regulation
CMGC_CDK_CDC2_CDK1_ST	Q9ULW0	TPX2	P06493	CDK1	S738	R744Q	744	Missense	distal	6	no	3.244	3.227	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	3.158	Down-regulation
CMGC_CDK_CDC2_CDK1_ST	P38398	BRCA1	P06493	CDK1	T528	V525A	525	Missense	distal	-3	no	3.308	3.370	EPSD	TCGA;COSMIC	3.158	Up-regulation
CMGC_CDK_CDC2_CDK1_ST	P38398	BRCA1	P06493	CDK1	T528	P529S	529	Missense	proximal	1	no	3.308	0.124	EPSD	TCGA;COSMIC	3.158	Loss
CMGC_CDK_CDC2_CDK1_ST	P38398	BRCA1	P06493	CDK1	T528	A524T	524	Missense	distal	-4	no	3.308	3.344	EPSD	TCGA;COSMIC	3.158	Up-regulation
CMGC_CDK_CDC2_CDK1_ST	P38398	BRCA1	P06493	CDK1	T967	E962A	962	Missense	distal	-5	no	3.517	3.440	EPSD	TCGA;COSMIC	3.158	Down-regulation
CMGC_CDK_CDC2_CDK1_ST	P38398	BRCA1	P06493	CDK1	S1009	E1013Q	1013	Missense	distal	4	no	3.117	3.160	EPSD	TCGA	3.158	Gain
CMGC_CDK_CDC2_CDK1_ST	O95835	LATS1	P06493	CDK1	S289	I288M	288	Missense	proximal	-1	no	3.292	3.182	EPSD	TCGA;ICGC;COSMIC	3.158	Down-regulation
CMGC_CDK_CDC2_CDK1_ST	O95835	LATS1	P06493	CDK1	S289	P292L	292	Missense	distal	3	no	3.292	3.159	EPSD	TCGA;ICGC;COSMIC	3.158	Down-regulation
CMGC_CDK_CDC2_CDK1_ST	O95835	LATS1	P06493	CDK1	S635	F641L	641	Missense	distal	6	no	3.266	3.253	EPSD	TCGA;ICGC;COSMIC	3.158	Down-regulation
CMGC_CDK_CDC2_CDK1_ST	O95835	LATS1	P06493	CDK1	S635	R630H	630	Missense	distal	-5	no	3.266	3.261	EPSD	TCGA;ICGC	3.158	Down-regulation
CMGC_CDK_CDC2_CDK1_ST	P29590	PML	P06493	CDK1	T196	R195C	195	Missense	proximal	-1	no	3.328	3.383	EPSD	TCGA;ICGC;COSMIC	3.158	Up-regulation
CMGC_CDK_CDC2_CDK1_ST	P29590	PML	P06493	CDK1	T196	S190C	190	Missense	distal	-6	no	3.328	3.345	EPSD	TCGA;ICGC;COSMIC	3.158	Up-regulation
CMGC_CDK_CDC2_CDK1_ST	P29590	PML	P06493	CDK1	T196	R195H	195	Missense	proximal	-1	no	3.328	3.352	EPSD	TCGA;ICGC;COSMIC	3.158	Up-regulation
CMGC_CDK_CDC2_CDK1_ST	P29590	PML	P06493	CDK1	S403	P410S	410	Missense	distal	7	no	3.446	3.444	EPSD	TCGA;ICGC;COSMIC	3.158	Down-regulation
CMGC_CDK_CDC2_CDK1_ST	P29590	PML	P06493	CDK1	S403	E405K	405	Missense	proximal	2	no	3.446	3.441	EPSD	TCGA;ICGC	3.158	Down-regulation
CMGC_CDK_CDC2_CDK1_ST	Q2M2I8	AAK1	P06493	CDK1	T389	A387V	387	Missense	proximal	-2	no	3.236	3.401	PhosphoSitePlus	TCGA;ICGC;COSMIC	3.158	Up-regulation
CMGC_CDK_CDC2_CDK1_ST	Q2M2I8	AAK1	P06493	CDK1	T620	L619V	619	Missense	proximal	-1	no	3.179	3.124	EPSD	TCGA;ICGC;COSMIC	3.158	Loss
CMGC_CDK_CDC2_CDK1_ST	Q2M2I8	AAK1	P06493	CDK1	T620	G617V	617	Missense	distal	-3	no	3.179	3.214	EPSD	TCGA;ICGC;COSMIC	3.158	Up-regulation
CMGC_CDK_CDC2_CDK1_ST	Q2M2I8	AAK1	P06493	CDK1	T620	K626T	626	Missense	distal	6	no	3.179	3.201	EPSD	TCGA;ICGC	3.158	Up-regulation
CMGC_CDK_CDC2_CDK1_ST	P49916	LIG3	P06493	CDK1	S242	S236C	236	Missense	distal	-6	no	3.449	3.466	EPSD	TCGA;ICGC;COSMIC	3.158	Up-regulation
CMGC_CDK_CDC2_CDK1_ST	P49916	LIG3	P06493	CDK1	S242	E238K	238	Missense	distal	-4	no	3.449	3.395	EPSD	TCGA;ICGC;COSMIC	3.158	Down-regulation
CMGC_CDK_CDC2_CDK1_ST	P49916	LIG3	P06493	CDK1	S913	V915L	915	Missense	proximal	2	no	3.734	3.740	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	3.158	Up-regulation
CMGC_CDK_CDC2_CDK1_ST	Q14203	DCTN1	P06493	CDK1	S105	G100A	100	Missense	distal	-5	no	3.163	3.014	EPSD	TCGA;ICGC;COSMIC	3.158	Loss
CMGC_CDK_CDC2_CDK1_ST	Q14203	DCTN1	P06493	CDK1	S105	D110Y	110	Missense	distal	5	no	3.163	3.193	EPSD	TCGA;ICGC;COSMIC	3.158	Up-regulation
CMGC_CDK_CDC2_CDK1_ST	Q14203	DCTN1	P06493	CDK1	S105	T103I	103	Missense	proximal	-2	no	3.163	3.296	EPSD	TCGA;ICGC;COSMIC	3.158	Up-regulation
CMGC_CDK_CDC2_CDK1_ST	Q14203	DCTN1	P06493	CDK1	S105	P106L	106	Missense	proximal	1	no	3.163	-0.523	EPSD	TCGA;COSMIC	3.158	Loss
CMGC_CDK_CDC2_CDK1_ST	Q14203	DCTN1	P06493	CDK1	S203	P209R	209	Missense	distal	6	no	3.392	3.405	EPSD	TCGA;COSMIC	3.158	Up-regulation
CMGC_CDK_CDC2_CDK1_ST	Q14203	DCTN1	P06493	CDK1	S212	P209R	209	Missense	distal	-3	no	3.207	3.180	PhosphoSitePlus	TCGA;COSMIC	3.158	Down-regulation
CMGC_CDK_CDC2_CDK1_ST	Q14203	DCTN1	P06493	CDK1	S1180	R1173H	1173	Missense	distal	-7	no	3.167	3.141	EPSD	TCGA;COSMIC	3.158	Loss
CMGC_CDK_CDC2_CDK1_ST	Q14203	DCTN1	P06493	CDK1	S1180	A1183T	1183	Missense	distal	3	no	3.167	3.079	EPSD	TCGA;COSMIC	3.158	Loss
CMGC_CDK_CDC2_CDK1_ST	Q14203	DCTN1	P06493	CDK1	S1180	R1173C	1173	Missense	distal	-7	no	3.167	3.088	EPSD	TCGA;COSMIC	3.158	Loss
CMGC_CDK_CDC2_CDK1_ST	O14715	RGPD8	P06493	CDK1	T19	R23P	23	Missense	distal	4	no	3.389	3.375	EPSD	TCGA;ICGC;COSMIC	3.158	Down-regulation
CMGC_CDK_CDC2_CDK1_ST	O14715	RGPD8	P06493	CDK1	T19	S21L	21	Missense	proximal	2	no	3.389	3.412	EPSD	TCGA;ICGC;COSMIC	3.158	Up-regulation
CMGC_CDK_CDC2_CDK1_ST	O14715	RGPD8	P06493	CDK1	S395	S400Y	400	Missense	distal	5	no	3.366	3.484	EPSD	TCGA;ICGC;COSMIC	3.158	Up-regulation
CMGC_CDK_CDC2_CDK1_ST	O14715	RGPD8	P06493	CDK1	T1152	P1153A	1153	Missense	proximal	1	no	3.362	2.472	EPSD	TCGA;COSMIC	3.158	Loss
CMGC_CDK_CDC2_CDK1_ST	O14715	RGPD8	P06493	CDK1	T1152	R1145W	1145	Missense	distal	-7	no	3.362	3.292	EPSD	TCGA;COSMIC	3.158	Down-regulation
CMGC_CDK_CDC2_CDK1_ST	O14715	RGPD8	P06493	CDK1	T1152	E1157K	1157	Missense	distal	5	no	3.362	3.314	EPSD	TCGA;COSMIC	3.158	Down-regulation
CMGC_CDK_CDC2_CDK1_ST	O14715	RGPD8	P06493	CDK1	T1152	F1159I	1159	Missense	distal	7	no	3.362	3.365	EPSD	TCGA;COSMIC	3.158	Up-regulation
CMGC_CDK_CDC2_CDK1_ST	O14715	RGPD8	P06493	CDK1	T1474	S1471Y	1471	Missense	distal	-3	no	3.379	3.346	EPSD	TCGA	3.158	Down-regulation
CMGC_CDK_CDC2_CDK1_ST	O14715	RGPD8	P06493	CDK1	S1486	E1485D	1485	Missense	proximal	-1	no	3.342	3.334	EPSD	TCGA;COSMIC	3.158	Down-regulation
CMGC_CDK_CDC2_CDK1_ST	O14715	RGPD8	P06493	CDK1	S1486	A1492V	1492	Missense	distal	6	no	3.342	3.294	EPSD	TCGA	3.158	Down-regulation
CMGC_CDK_CDC2_CDK1_ST	P35251	RFC1	P06493	CDK1	S99	R100P	100	Missense	proximal	1	no	-0.347	3.262	EPSD	TCGA;ICGC;COSMIC	3.158	Gain
CMGC_CDK_CDC2_CDK1_ST	P35251	RFC1	P06493	CDK1	T161	L166P	166	Missense	distal	5	no	3.642	3.457	EPSD	TCGA	3.158	Down-regulation
CMGC_CDK_CDC2_CDK1_ST	O95239	KIF4A	P06493	CDK1	S1013	D1015N	1015	Missense	proximal	2	no	3.656	3.652	EPSD	TCGA;ICGC;COSMIC	3.158	Down-regulation
CMGC_CDK_CDC2_CDK1_ST	O95239	KIF4A	P06493	CDK1	S1013	P1007S	1007	Missense	distal	-6	no	3.656	3.655	EPSD	TCGA;ICGC;COSMIC	3.158	Down-regulation
CMGC_CDK_CDC2_CDK1_ST	O95239	KIF4A	P06493	CDK1	S1013	S1017Y	1017	Missense	distal	4	no	3.656	3.587	EPSD	TCGA;ICGC;COSMIC	3.158	Down-regulation
CMGC_CDK_CDC2_CDK1_ST	O95239	KIF4A	P06493	CDK1	S1225	S1225Y	1225	Missense	central	0	yes	3.430	0.000	EPSD	TCGA;ICGC;COSMIC	3.158	Loss
CMGC_CDK_CDC2_CDK1_ST	O95239	KIF4A	P06493	CDK1	S1225	E1228K	1228	Missense	distal	3	no	3.430	3.535	EPSD	TCGA;ICGC;COSMIC	3.158	Up-regulation
CMGC_CDK_CDC2_CDK1_ST	O95239	KIF4A	P06493	CDK1	S1225	A1231V	1231	Missense	distal	6	no	3.430	3.383	EPSD	TCGA;ICGC;COSMIC	3.158	Down-regulation
CMGC_CDK_CDC2_CDK1_ST	P36956	SREBF1	P06493	CDK1	T105	P106A	106	Missense	proximal	1	no	3.336	2.447	EPSD	TCGA;COSMIC	3.158	Loss
CMGC_CDK_CDC2_CDK1_ST	P36956	SREBF1	P06493	CDK1	T105	S98P	98	Missense	distal	-7	no	3.336	3.296	EPSD	TCGA;COSMIC	3.158	Down-regulation
CMGC_CDK_CDC2_CDK1_ST	P05067	APP	P06493	CDK1	T743	R747P	747	Missense	distal	4	no	3.318	3.304	PhosphoSitePlus	TCGA;COSMIC	3.158	Down-regulation
CMGC_CDK_CDC2_CDK1_ST	P05067	APP	P06493	CDK1	T743	R747C	747	Missense	distal	4	no	3.318	3.254	PhosphoSitePlus	TCGA;COSMIC;GDSC	3.158	Down-regulation
CMGC_CDK_CDC2_CDK1_ST	P05067	APP	P06493	CDK1	T743	R747H	747	Missense	distal	4	no	3.318	3.277	PhosphoSitePlus	TCGA;COSMIC	3.158	Down-regulation
CMGC_CDK_CDC2_CDK1_ST	P17706	PTPN2	P06493	CDK1	S52	R47G	47	Missense	distal	-5	no	3.333	3.401	EPSD	TCGA;ICGC;COSMIC	3.158	Up-regulation
CMGC_CDK_CDC2_CDK1_ST	P17706	PTPN2	P06493	CDK1	S52	R58C	58	Missense	distal	6	no	3.333	3.296	EPSD	TCGA;ICGC;COSMIC	3.158	Down-regulation
CMGC_CDK_CDC2_CDK1_ST	P17706	PTPN2	P06493	CDK1	S298	S298C	298	Missense	central	0	yes	3.171	0.000	EPSD	TCGA;COSMIC	3.158	Loss
CMGC_CDK_CDC2_CDK1_ST	P17706	PTPN2	P06493	CDK1	S298	S298Y	298	Missense	central	0	yes	3.171	0.000	EPSD	TCGA;ICGC;COSMIC	3.158	Loss
CMGC_CDK_CDC2_CDK1_ST	P17706	PTPN2	P06493	CDK1	S298	P299S	299	Missense	proximal	1	no	3.171	-0.014	EPSD	TCGA;ICGC;COSMIC	3.158	Loss
CMGC_CDK_CDC2_CDK1_ST	P17706	PTPN2	P06493	CDK1	S304	S298C	298	Missense	distal	-6	no	3.397	3.413	PhosphoSitePlus	TCGA;COSMIC	3.158	Up-regulation
CMGC_CDK_CDC2_CDK1_ST	P17706	PTPN2	P06493	CDK1	S304	S298Y	298	Missense	distal	-6	no	3.397	3.414	PhosphoSitePlus	TCGA;ICGC;COSMIC	3.158	Up-regulation
CMGC_CDK_CDC2_CDK1_ST	P17706	PTPN2	P06493	CDK1	S304	P299S	299	Missense	distal	-5	no	3.397	3.374	PhosphoSitePlus	TCGA;ICGC;COSMIC	3.158	Down-regulation
CMGC_CDK_CDC2_CDK1_ST	Q13009	TIAM1	P06493	CDK1	T61	R57Q	57	Missense	distal	-4	no	3.365	3.383	EPSD	TCGA;ICGC;COSMIC	3.158	Up-regulation
CMGC_CDK_CDC2_CDK1_ST	Q13009	TIAM1	P06493	CDK1	S1018	S1018N	1018	Missense	central	0	yes	3.433	0.000	EPSD	TCGA;COSMIC	3.158	Loss
CMGC_CDK_CDC2_CDK1_ST	Q13009	TIAM1	P06493	CDK1	S1018	P1021T	1021	Missense	distal	3	no	3.433	3.449	EPSD	TCGA;COSMIC	3.158	Up-regulation
CMGC_CDK_CDC2_CDK1_ST	Q13009	TIAM1	P06493	CDK1	S1466	A1464T	1464	Missense	proximal	-2	no	3.213	3.293	PhosphoSitePlus	TCGA;COSMIC;CCLE	3.158	Up-regulation
CMGC_CDK_CDC2_CDK1_ST	Q13009	TIAM1	P06493	CDK1	S1466	P1467L	1467	Missense	proximal	1	no	3.213	-0.473	PhosphoSitePlus	TCGA;COSMIC	3.158	Loss
CMGC_CDK_CDC2_CDK1_ST	Q9Y3Z3	SAMHD1	P06493	CDK1	T21	R20K	20	Missense	proximal	-1	no	3.093	3.163	EPSD	TCGA;ICGC	3.158	Gain
CMGC_CDK_CDC2_CDK1_ST	Q9Y3Z3	SAMHD1	P06493	CDK1	T21	R20I	20	Missense	proximal	-1	no	3.093	3.229	EPSD	TCGA;ICGC;COSMIC	3.158	Gain
CMGC_CDK_CDC2_CDK1_ST	Q9Y3Z3	SAMHD1	P06493	CDK1	T25	S27F	27	Missense	proximal	2	no	3.616	3.638	EPSD	TCGA;ICGC;COSMIC	3.158	Up-regulation
CMGC_CDK_CDC2_CDK1_ST	Q9Y3Z3	SAMHD1	P06493	CDK1	T25	R20K	20	Missense	distal	-5	no	3.616	3.642	EPSD	TCGA;ICGC	3.158	Up-regulation
CMGC_CDK_CDC2_CDK1_ST	Q9Y3Z3	SAMHD1	P06493	CDK1	T25	R20I	20	Missense	distal	-5	no	3.616	3.688	EPSD	TCGA;ICGC;COSMIC	3.158	Up-regulation
CMGC_CDK_CDC2_CDK1_ST	Q9Y3Z3	SAMHD1	P06493	CDK1	S33	S27F	27	Missense	distal	-6	no	3.315	3.339	EPSD	TCGA;ICGC;COSMIC	3.158	Up-regulation
CMGC_CDK_CDC2_CDK1_ST	Q9Y3Z3	SAMHD1	P06493	CDK1	S33	E37A	37	Missense	distal	4	no	3.315	3.419	EPSD	TCGA;ICGC;COSMIC	3.158	Up-regulation
CMGC_CDK_CDC2_CDK1_ST	Q9Y3Z3	SAMHD1	P06493	CDK1	S33	H39Y	39	Missense	distal	6	no	3.315	3.289	EPSD	TCGA;ICGC;COSMIC	3.158	Down-regulation
CMGC_CDK_CDC2_CDK1_ST	O00267	SUPT5H	P06493	CDK1	S686	F684C	684	Missense	proximal	-2	no	3.414	3.363	EPSD	TCGA;ICGC;COSMIC	3.158	Down-regulation
CMGC_CDK_CDC2_CDK1_ST	O00267	SUPT5H	P06493	CDK1	T791	D795Y	795	Missense	distal	4	no	3.587	3.562	EPSD	TCGA;ICGC;COSMIC	3.158	Down-regulation
CMGC_CDK_CDC2_CDK1_ST	O00267	SUPT5H	P06493	CDK1	T791	G796D	796	Missense	distal	5	no	3.587	3.492	EPSD	TCGA;ICGC	3.158	Down-regulation
CMGC_CDK_CDC2_CDK1_ST	O00267	SUPT5H	P06493	CDK1	T967	G969C	969	Missense	proximal	2	no	3.199	3.190	EPSD	TCGA;ICGC;COSMIC	3.158	Down-regulation
CMGC_CDK_CDC2_CDK1_ST	O00267	SUPT5H	P06493	CDK1	T967	S970L	970	Missense	distal	3	no	3.199	3.016	EPSD	TCGA;ICGC;COSMIC	3.158	Loss
CMGC_CDK_CDC2_CDK1_ST	Q9UKX7	NUP50	P06493	CDK1	S221	P222A	222	Missense	proximal	1	no	3.181	2.292	PhosphoSitePlus	TCGA;COSMIC	3.158	Loss
CMGC_CDK_CDC2_CDK1_ST	Q9UKX7	NUP50	P06493	CDK1	S221	E218V	218	Missense	distal	-3	no	3.181	3.188	PhosphoSitePlus	TCGA;COSMIC	3.158	Up-regulation
CMGC_CDK_CDC2_CDK1_ST	Q96KB5	PBK	P06493	CDK1	T9	K12R	12	Missense	distal	3	no	3.177	3.194	PhosphoSitePlus	TCGA;COSMIC	3.158	Up-regulation
CMGC_CDK_CDC2_CDK1_ST	O14745	SLC9A3R1	P06493	CDK1	S280	P283T	283	Missense	distal	3	no	3.201	3.217	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	3.158	Up-regulation
CMGC_CDK_CDC2_CDK1_ST	P54578	USP14	P06493	CDK1	T459	R465L	465	Missense	distal	6	no	3.815	3.746	EPSD	TCGA;COSMIC	3.158	Down-regulation
CMGC_CDK_CDC2_CDK1_ST	P54578	USP14	P06493	CDK1	T459	S456N	456	Missense	distal	-3	no	3.815	3.799	EPSD	TCGA;COSMIC	3.158	Down-regulation
CMGC_CDK_CDC2_CDK1_ST	P54578	USP14	P06493	CDK1	T459	K454T	454	Missense	distal	-5	no	3.815	3.729	EPSD	TCGA;COSMIC	3.158	Down-regulation
CMGC_CDK_CDC2_CDK1_ST	P54578	USP14	P06493	CDK1	T459	V458A	458	Missense	proximal	-1	no	3.815	3.616	EPSD	TCGA;COSMIC	3.158	Down-regulation
CMGC_CDK_CDC2_CDK1_ST	P54578	USP14	P06493	CDK1	T459	D462Y	462	Missense	distal	3	no	3.815	3.809	EPSD	TCGA	3.158	Down-regulation
CMGC_CDK_CDC2_CDK1_ST	P23769	GATA2	P06493	CDK1	S119	S119R	119	Missense	central	0	yes	3.475	0.000	EPSD	TCGA;ICGC	3.158	Loss
CMGC_CDK_CDC2_CDK1_ST	P23769	GATA2	P06493	CDK1	S119	T124M	124	Missense	distal	5	no	3.475	3.538	EPSD	TCGA;ICGC;COSMIC	3.158	Up-regulation
CMGC_CDK_CDC2_CDK1_ST	P23769	GATA2	P06493	CDK1	T303	R308Q	308	Missense	distal	5	no	3.244	3.268	EPSD	TCGA;ICGC;COSMIC	3.158	Up-regulation
CMGC_CDK_CDC2_CDK1_ST	P23769	GATA2	P06493	CDK1	T303	A302T	302	Missense	proximal	-1	no	3.244	3.271	EPSD	TCGA;ICGC;COSMIC	3.158	Up-regulation
CMGC_CDK_CDC2_CDK1_ST	P23769	GATA2	P06493	CDK1	T303	A300S	300	Missense	distal	-3	no	3.244	3.202	EPSD	TCGA;ICGC;COSMIC	3.158	Down-regulation
CMGC_CDK_CDC2_CDK1_ST	Q96C19	EFHD2	P06493	CDK1	S74	V79I	79	Missense	distal	5	no	3.259	3.273	PhosphoSitePlus	TCGA;ICGC;COSMIC	3.158	Up-regulation
CMGC_CDK_CDC2_CDK1_ST	O14980	XPO1	P06493	CDK1	S384	S387C	387	Missense	distal	3	no	3.405	3.356	EPSD	TCGA;ICGC;COSMIC	3.158	Down-regulation
CMGC_CDK_CDC2_CDK1_ST	O14980	XPO1	P06493	CDK1	S384	E383G	383	Missense	proximal	-1	no	3.405	3.531	EPSD	TCGA;ICGC	3.158	Up-regulation
CMGC_CDK_CDC2_CDK1_ST	O14980	XPO1	P06493	CDK1	S391	S387C	387	Missense	distal	-4	no	3.438	3.302	PhosphoSitePlus	TCGA;ICGC;COSMIC	3.158	Down-regulation
CMGC_CDK_CDC2_CDK1_ST	O14980	XPO1	P06493	CDK1	S391	G396V	396	Missense	distal	5	no	3.438	3.405	PhosphoSitePlus	TCGA;ICGC;COSMIC	3.158	Down-regulation
CMGC_CDK_CDC2_CDK1_ST	P42166	TMPO	P06493	CDK1	S370	S365I	365	Missense	distal	-5	no	3.131	3.261	EPSD	TCGA;ICGC;COSMIC	3.158	Gain
CMGC_CDK_CDC2_CDK1_ST	P42166	TMPO	P06493	CDK1	S424	P430L	430	Missense	distal	6	no	3.464	3.408	PhosphoSitePlus	TCGA;ICGC;COSMIC	3.158	Down-regulation
CMGC_CDK_CDC2_CDK1_ST	P42166	TMPO	P06493	CDK1	S424	R427I	427	Missense	distal	3	no	3.464	3.297	PhosphoSitePlus	TCGA;ICGC	3.158	Down-regulation
CMGC_CDK_CDC2_CDK1_ST	P42166	TMPO	P06493	CDK1	T671	G676R	676	Missense	distal	5	no	3.259	3.067	EPSD	TCGA;ICGC;COSMIC	3.158	Loss
CMGC_CDK_CDC2_CDK1_ST	P42166	TMPO	P06493	CDK1	T671	S664Y	664	Missense	distal	-7	no	3.259	3.144	EPSD	TCGA;ICGC;COSMIC	3.158	Loss
CMGC_CDK_CDC2_CDK1_ST	Q13501	SQSTM1	P06493	CDK1	S170	G173R	173	Missense	distal	3	no	3.109	3.302	EPSD	TCGA;ICGC;COSMIC	3.158	Gain
CMGC_CDK_CDC2_CDK1_ST	Q8IX03	WWC1	P06493	CDK1	S535	R537C	537	Missense	proximal	2	no	3.395	3.402	EPSD	TCGA;ICGC;COSMIC	3.158	Up-regulation
CMGC_CDK_CDC2_CDK1_ST	Q8IX03	WWC1	P06493	CDK1	S535	P528S	528	Missense	distal	-7	no	3.395	3.435	EPSD	TCGA;ICGC;COSMIC	3.158	Up-regulation
CMGC_CDK_CDC2_CDK1_ST	Q8IX03	WWC1	P06493	CDK1	S535	L540F	540	Missense	distal	5	no	3.395	3.348	EPSD	TCGA;ICGC;COSMIC	3.158	Down-regulation
CMGC_CDK_CDC2_CDK1_ST	Q8IX03	WWC1	P06493	CDK1	S535	P536S	536	Missense	proximal	1	no	3.395	0.210	EPSD	TCGA;ICGC;COSMIC	3.158	Loss
CMGC_CDK_CDC2_CDK1_ST	Q8IX03	WWC1	P06493	CDK1	S535	S533F	533	Missense	proximal	-2	no	3.395	3.463	EPSD	TCGA;ICGC;COSMIC	3.158	Up-regulation
CMGC_CDK_CDC2_CDK1_ST	Q8IX03	WWC1	P06493	CDK1	S535	M531I	531	Missense	distal	-4	no	3.395	3.332	EPSD	TCGA;ICGC;COSMIC	3.158	Down-regulation
CMGC_CDK_CDC2_CDK1_ST	Q8IX03	WWC1	P06493	CDK1	S542	P549L	549	Missense	distal	7	no	3.677	3.705	PhosphoSitePlus;EPSD	TCGA;ICGC;COSMIC	3.158	Up-regulation
CMGC_CDK_CDC2_CDK1_ST	Q8IX03	WWC1	P06493	CDK1	S542	R537C	537	Missense	distal	-5	no	3.677	3.710	PhosphoSitePlus;EPSD	TCGA;ICGC;COSMIC	3.158	Up-regulation
CMGC_CDK_CDC2_CDK1_ST	Q8IX03	WWC1	P06493	CDK1	S542	L540F	540	Missense	proximal	-2	no	3.677	3.698	PhosphoSitePlus;EPSD	TCGA;ICGC;COSMIC	3.158	Up-regulation
CMGC_CDK_CDC2_CDK1_ST	Q8IX03	WWC1	P06493	CDK1	S542	S548F	548	Missense	distal	6	no	3.677	3.626	PhosphoSitePlus;EPSD	TCGA;ICGC;COSMIC	3.158	Down-regulation
CMGC_CDK_CDC2_CDK1_ST	Q8IX03	WWC1	P06493	CDK1	S542	P536S	536	Missense	distal	-6	no	3.677	3.676	PhosphoSitePlus;EPSD	TCGA;ICGC;COSMIC	3.158	Down-regulation
CMGC_CDK_CDC2_CDK1_ST	Q8IX03	WWC1	P06493	CDK1	S548	P549L	549	Missense	proximal	1	no	3.675	-0.011	EPSD	TCGA;ICGC;COSMIC	3.158	Loss
CMGC_CDK_CDC2_CDK1_ST	Q8IX03	WWC1	P06493	CDK1	S548	M551I	551	Missense	distal	3	no	3.675	3.617	EPSD	TCGA;ICGC;COSMIC	3.158	Down-regulation
CMGC_CDK_CDC2_CDK1_ST	Q8IX03	WWC1	P06493	CDK1	S548	S548F	548	Missense	central	0	yes	3.675	0.000	EPSD	TCGA;ICGC;COSMIC	3.158	Loss
CMGC_CDK_CDC2_CDK1_ST	Q8IX03	WWC1	P06493	CDK1	T895	P898S	898	Missense	distal	3	no	3.526	3.577	EPSD	TCGA;ICGC;COSMIC	3.158	Up-regulation
CMGC_CDK_CDC2_CDK1_ST	Q8IX03	WWC1	P06493	CDK1	T895	S899P	899	Missense	distal	4	no	3.526	3.530	EPSD	TCGA;ICGC;COSMIC	3.158	Up-regulation
CMGC_CDK_CDC2_CDK1_ST	Q8IX03	WWC1	P06493	CDK1	T912	S914F	914	Missense	proximal	2	no	3.247	3.269	EPSD	TCGA;ICGC;COSMIC	3.158	Up-regulation
CMGC_CDK_CDC2_CDK1_ST	Q8IX03	WWC1	P06493	CDK1	T912	P913L	913	Missense	proximal	1	no	3.247	-0.440	EPSD	TCGA	3.158	Loss
CMGC_CDK_CDC2_CDK1_ST	Q14244	MAP7	P06493	CDK1	S209	N208S	208	Missense	proximal	-1	no	3.353	3.262	PhosphoSitePlus	TCGA	3.158	Down-regulation
CMGC_CDK_CDC2_CDK1_ST	Q14244	MAP7	P06493	CDK1	S714	I717S	717	Missense	distal	3	no	3.464	3.561	EPSD	TCGA	3.158	Up-regulation
CMGC_CDK_CDC2_CDK1_ST	Q96T23	RSF1	P06493	CDK1	T241	Q247H	247	Missense	distal	6	no	3.210	3.208	EPSD	TCGA;COSMIC	3.158	Down-regulation
CMGC_CDK_CDC2_CDK1_ST	Q96T23	RSF1	P06493	CDK1	S570	K565I	565	Missense	distal	-5	no	3.340	3.386	EPSD	TCGA;COSMIC	3.158	Up-regulation
CMGC_CDK_CDC2_CDK1_ST	Q96T23	RSF1	P06493	CDK1	S604	E608Q	608	Missense	distal	4	no	3.244	3.287	EPSD	TCGA;COSMIC	3.158	Up-regulation
CMGC_CDK_CDC2_CDK1_ST	Q96T23	RSF1	P06493	CDK1	S604	P611L	611	Missense	distal	7	no	3.244	3.272	EPSD	TCGA;COSMIC	3.158	Up-regulation
CMGC_CDK_CDC2_CDK1_ST	Q96T23	RSF1	P06493	CDK1	S629	I634M	634	Missense	distal	5	no	3.551	3.456	EPSD	TCGA;COSMIC	3.158	Down-regulation
CMGC_CDK_CDC2_CDK1_ST	P24864	CCNE1	P06493	CDK1	T395	T395I	395	Missense	central	0	yes	3.467	0.000	EPSD	TCGA;ICGC;COSMIC	3.158	Loss
CMGC_CDK_CDC2_CDK1_ST	P24864	CCNE1	P06493	CDK1	T395	P396L	396	Missense	proximal	1	no	3.467	-0.219	EPSD	TCGA;ICGC;COSMIC	3.158	Loss
CMGC_CDK_CDC2_CDK1_ST	O43521	BCL2L11	P06493	CDK1	S59	P63S	63	Missense	distal	4	no	3.382	3.378	EPSD	TCGA;ICGC;COSMIC	3.158	Down-regulation
CMGC_CDK_CDC2_CDK1_ST	O43521	BCL2L11	P06493	CDK1	S69	A68V	68	Missense	proximal	-1	no	3.155	3.355	EPSD	TCGA;ICGC;COSMIC	3.158	Gain
CMGC_CDK_CDC2_CDK1_ST	Q96C36	PYCR2	P06493	CDK1	T301	T296I	296	Missense	distal	-5	no	3.300	3.432	EPSD	TCGA;ICGC;COSMIC	3.158	Up-regulation
CMGC_CDK_CDC2_CDK1_ST	Q96C36	PYCR2	P06493	CDK1	T301	S294F	294	Missense	distal	-7	no	3.300	3.154	EPSD	TCGA;ICGC;COSMIC	3.158	Loss
CMGC_CDK_CDC2_CDK1_ST	Q06413	MEF2C	P06493	CDK1	S98	A103V	103	Missense	distal	5	no	2.978	3.186	EPSD	TCGA;ICGC	3.158	Gain
CMGC_CDK_CDC2_CDK1_ST	Q06413	MEF2C	P06493	CDK1	S110	A103V	103	Missense	distal	-7	no	3.200	3.048	EPSD	TCGA;ICGC	3.158	Loss
CMGC_CDK_CDC2_CDK1_ST	Q06413	MEF2C	P06493	CDK1	S110	S106F	106	Missense	distal	-4	no	3.200	3.053	EPSD	TCGA;ICGC;COSMIC	3.158	Loss
CMGC_CDK_CDC2_CDK1_ST	O43663	PRC1	P06493	CDK1	S513	S516Y	516	Missense	distal	3	no	3.253	3.177	EPSD	TCGA;ICGC;COSMIC	3.158	Down-regulation
CMGC_CDK_CDC2_CDK1_ST	P33993	MCM7	P06493	CDK1	S365	G360R	360	Missense	distal	-5	no	3.344	3.275	EPSD	TCGA;ICGC;COSMIC	3.158	Down-regulation
CMGC_CDK_CDC2_CDK1_ST	P33993	MCM7	P06493	CDK1	S365	V359F	359	Missense	distal	-6	no	3.344	3.348	EPSD	TCGA;ICGC;COSMIC	3.158	Up-regulation
CMGC_CDK_CDC2_CDK1_ST	P22234	PAICS	P06493	CDK1	S27	E23K	23	Missense	distal	-4	no	3.186	3.132	PhosphoSitePlus	TCGA;ICGC;CCLE	3.158	Loss
CMGC_CDK_CDC2_CDK1_ST	Q2NKX8	ERCC6L	P06493	CDK1	S14	H20Y	20	Missense	distal	6	no	3.158	3.133	EPSD	TCGA;ICGC;COSMIC	3.158	Loss
CMGC_CDK_CDC2_CDK1_ST	Q2NKX8	ERCC6L	P06493	CDK1	S1188	A1193G	1193	Missense	distal	5	no	3.965	4.205	EPSD	TCGA;ICGC;COSMIC	3.158	Up-regulation
CMGC_CDK_CDC2_CDK1_ST	Q2NKX8	ERCC6L	P06493	CDK1	S1188	K1192T	1192	Missense	distal	4	no	3.965	3.986	EPSD	TCGA;ICGC;COSMIC	3.158	Up-regulation
CMGC_CDK_CDC2_CDK1_ST	P49821	NDUFV1	P06493	CDK1	T383	R386C	386	Missense	distal	3	no	3.629	3.510	PhosphoSitePlus	TCGA;ICGC;COSMIC	3.158	Down-regulation
CMGC_CDK_CDC2_CDK1_ST	P18858	LIG1	P06493	CDK1	T183	T183M	183	Missense	central	0	yes	3.364	0.000	EPSD	TCGA;COSMIC;GDSC	3.158	Loss
CMGC_CDK_CDC2_CDK1_ST	P18858	LIG1	P06493	CDK1	T233	T227M	227	Missense	distal	-6	no	3.337	3.348	EPSD	TCGA;ICGC;COSMIC	3.158	Up-regulation
CMGC_CDK_CDC2_CDK1_ST	P18858	LIG1	P06493	CDK1	S323	P325S	325	Missense	proximal	2	no	3.431	3.429	EPSD	TCGA;COSMIC	3.158	Down-regulation
CMGC_CDK_CDC2_CDK1_ST	P18858	LIG1	P06493	CDK1	S323	R317C	317	Missense	distal	-6	no	3.431	3.440	EPSD	TCGA;COSMIC	3.158	Up-regulation
CMGC_CDK_CDC2_CDK1_ST	P18858	LIG1	P06493	CDK1	S323	A321T	321	Missense	proximal	-2	no	3.431	3.511	EPSD	TCGA;COSMIC	3.158	Up-regulation
CMGC_CDK_CDC2_CDK1_ST	P18858	LIG1	P06493	CDK1	S323	S323L	323	Missense	central	0	yes	3.431	0.000	EPSD	TCGA;COSMIC	3.158	Loss
CMGC_CDK_CDC2_CDK1_ST	P18858	LIG1	P06493	CDK1	S323	S318F	318	Missense	distal	-5	no	3.431	3.541	EPSD	TCGA;COSMIC	3.158	Up-regulation
CMGC_CDK_CDC2_CDK1_ST	P26358	DNMT1	P06493	CDK1	S714	M712I	712	Missense	proximal	-2	no	3.592	3.668	EPSD	TCGA;ICGC;COSMIC	3.158	Up-regulation
CMGC_CDK_CDC2_CDK1_ST	O00399	DCTN6	P06493	CDK1	T71	D76Y	76	Missense	distal	5	no	3.921	3.951	EPSD	TCGA;ICGC	3.158	Up-regulation
CMGC_CDK_CDC2_CDK1_ST	O00399	DCTN6	P06493	CDK1	T71	D76N	76	Missense	distal	5	no	3.921	3.874	EPSD	TCGA;ICGC	3.158	Down-regulation
CMGC_CDK_CDC2_CDK1_ST	Q9Y4H2	IRS2	P06493	CDK1	T657	D650Y	650	Missense	distal	-7	no	3.213	3.159	EPSD	TCGA;ICGC	3.158	Down-regulation
CMGC_CDK_CDC2_CDK1_ST	Q8WX93	PALLD	P06493	CDK1	T100	A106E	106	Missense	distal	6	no	3.428	3.396	EPSD	TCGA;ICGC;COSMIC	3.158	Down-regulation
CMGC_CDK_CDC2_CDK1_ST	Q8WX93	PALLD	P06493	CDK1	T100	P101H	101	Missense	proximal	1	no	3.428	0.744	EPSD	TCGA;COSMIC	3.158	Loss
CMGC_CDK_CDC2_CDK1_ST	Q8WX93	PALLD	P06493	CDK1	T100	Q95H	95	Missense	distal	-5	no	3.428	3.456	EPSD	TCGA;COSMIC	3.158	Up-regulation
CMGC_CDK_CDC2_CDK1_ST	Q8WX93	PALLD	P06493	CDK1	T147	R143C	143	Missense	distal	-4	no	3.491	3.421	EPSD	TCGA;COSMIC	3.158	Down-regulation
CMGC_CDK_CDC2_CDK1_ST	Q8WX93	PALLD	P06493	CDK1	T147	G144R	144	Missense	distal	-3	no	3.491	3.518	EPSD	TCGA;COSMIC	3.158	Up-regulation
CMGC_CDK_CDC2_CDK1_ST	Q8WX93	PALLD	P06493	CDK1	T147	R143S	143	Missense	distal	-4	no	3.491	3.557	EPSD	TCGA;COSMIC	3.158	Up-regulation
CMGC_CDK_CDC2_CDK1_ST	Q8WX93	PALLD	P06493	CDK1	T147	P148L	148	Missense	proximal	1	no	3.491	-0.196	EPSD	TCGA;COSMIC	3.158	Loss
CMGC_CDK_CDC2_CDK1_ST	Q8WX93	PALLD	P06493	CDK1	T147	S149G	149	Missense	proximal	2	no	3.491	3.514	EPSD	TCGA;COSMIC	3.158	Up-regulation
CMGC_CDK_CDC2_CDK1_ST	Q8WX93	PALLD	P06493	CDK1	S484	S484F	484	Missense	central	0	yes	3.166	0.000	EPSD	TCGA;COSMIC	3.158	Loss
CMGC_CDK_CDC2_CDK1_ST	Q8WX93	PALLD	P06493	CDK1	S641	L640R	640	Missense	proximal	-1	no	3.856	3.716	EPSD;PhosphoSitePlus	TCGA;ICGC	3.158	Down-regulation
CMGC_CDK_CDC2_CDK1_ST	Q8WX93	PALLD	P06493	CDK1	S641	A637S	637	Missense	distal	-4	no	3.856	3.883	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	3.158	Up-regulation
CMGC_CDK_CDC2_CDK1_ST	Q8WX93	PALLD	P06493	CDK1	S641	P648L	648	Missense	distal	7	no	3.856	3.884	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	3.158	Up-regulation
CMGC_CDK_CDC2_CDK1_ST	O60285	NUAK1	P06493	CDK1	S325	R330Q	330	Missense	distal	5	no	3.139	3.163	EPSD	TCGA;ICGC;COSMIC;GDSC;CCLE	3.158	Gain
CMGC_CDK_CDC2_CDK1_ST	O60285	NUAK1	P06493	CDK1	S445	P443S	443	Missense	proximal	-2	no	3.188	3.314	PhosphoSitePlus	TCGA;ICGC;COSMIC	3.158	Up-regulation
CMGC_CDK_CDC2_CDK1_ST	O60285	NUAK1	P06493	CDK1	S445	G452E	452	Missense	distal	7	no	3.188	3.174	PhosphoSitePlus	TCGA;ICGC;COSMIC	3.158	Down-regulation
CMGC_CDK_CDC2_CDK1_ST	O60285	NUAK1	P06493	CDK1	S445	P451L	451	Missense	distal	6	no	3.188	3.132	PhosphoSitePlus	TCGA;ICGC;COSMIC	3.158	Loss
CMGC_CDK_CDC2_CDK1_ST	O60285	NUAK1	P06493	CDK1	S455	T461M	461	Missense	distal	6	no	3.500	3.475	EPSD	TCGA;ICGC;COSMIC	3.158	Down-regulation
CMGC_CDK_CDC2_CDK1_ST	O60285	NUAK1	P06493	CDK1	S455	S459L	459	Missense	distal	4	no	3.500	3.381	EPSD	TCGA;ICGC;COSMIC	3.158	Down-regulation
CMGC_CDK_CDC2_CDK1_ST	O60285	NUAK1	P06493	CDK1	S455	G452E	452	Missense	distal	-3	no	3.500	3.527	EPSD	TCGA;ICGC;COSMIC	3.158	Up-regulation
CMGC_CDK_CDC2_CDK1_ST	O60285	NUAK1	P06493	CDK1	S455	P451L	451	Missense	distal	-4	no	3.500	3.356	EPSD	TCGA;ICGC;COSMIC	3.158	Down-regulation
CMGC_CDK_CDC2_CDK1_ST	O60285	NUAK1	P06493	CDK1	S542	A539S	539	Missense	distal	-3	no	3.304	3.261	EPSD	TCGA;ICGC;COSMIC	3.158	Down-regulation
CMGC_CDK_CDC2_CDK1_ST	O60285	NUAK1	P06493	CDK1	S542	M545I	545	Missense	distal	3	no	3.304	3.245	EPSD	TCGA;ICGC;COSMIC	3.158	Down-regulation
CMGC_CDK_CDC2_CDK1_ST	O60285	NUAK1	P06493	CDK1	S542	V541A	541	Missense	proximal	-1	no	3.304	3.104	EPSD	TCGA;ICGC;COSMIC	3.158	Loss
CMGC_CDK_CDC2_CDK1_ST	P61978	HNRNPK	P06493	CDK1	S284	M283V	283	Missense	proximal	-1	no	3.122	3.179	EPSD	TCGA;ICGC;COSMIC	3.158	Gain
CMGC_CDK_CDC2_CDK1_ST	P20338	RAB4A	P06493	CDK1	S204	R207H	207	Missense	distal	3	no	3.259	3.167	PhosphoSitePlus	TCGA;ICGC;COSMIC	3.158	Down-regulation
CMGC_CDK_CDC2_CDK1_ST	P20338	RAB4A	P06493	CDK1	S204	A210V	210	Missense	distal	6	no	3.259	3.211	PhosphoSitePlus	TCGA;ICGC;COSMIC	3.158	Down-regulation
CMGC_CDK_CDC2_CDK1_ST	P20338	RAB4A	P06493	CDK1	S204	P211S	211	Missense	distal	7	no	3.259	3.257	PhosphoSitePlus	TCGA;ICGC;COSMIC	3.158	Down-regulation
CMGC_CDK_CDC2_CDK1_ST	P20338	RAB4A	P06493	CDK1	S204	R207C	207	Missense	distal	3	no	3.259	3.140	PhosphoSitePlus	TCGA;ICGC;COSMIC;GDSC;CCLE	3.158	Loss
CMGC_CDK_CDC2_CDK1_ST	P20338	RAB4A	P06493	CDK1	S204	P205L	205	Missense	proximal	1	no	3.259	-0.427	PhosphoSitePlus	TCGA;ICGC;COSMIC	3.158	Loss
CMGC_CDK_CDC2_CDK1_ST	P20338	RAB4A	P06493	CDK1	S204	A197T	197	Missense	distal	-7	no	3.259	3.252	PhosphoSitePlus	TCGA;ICGC	3.158	Down-regulation
CMGC_CDK_CDC2_CDK1_ST	P20338	RAB4A	P06493	CDK1	S204	S204L	204	Missense	central	0	yes	3.259	0.000	PhosphoSitePlus	TCGA;ICGC;COSMIC	3.158	Loss
CMGC_CDK_CDC2_CDK1_ST	P20338	RAB4A	P06493	CDK1	S204	A208T	208	Missense	distal	4	no	3.259	3.207	PhosphoSitePlus	TCGA;ICGC;COSMIC	3.158	Down-regulation
CMGC_CDK_CDC2_CDK1_ST	Q9H9S0	NANOG	P06493	CDK1	S65	M58I	58	Missense	distal	-7	no	3.327	3.242	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC;CCLE	3.158	Down-regulation
CMGC_CDK_CDC2_CDK1_ST	Q9H9S0	NANOG	P06493	CDK1	S65	S68Y	68	Missense	distal	3	no	3.327	3.251	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	3.158	Down-regulation
CMGC_CDK_CDC2_CDK1_ST	Q8NFH8	REPS2	P06493	CDK1	S191	T185K	185	Missense	distal	-6	no	3.464	3.476	EPSD	TCGA;COSMIC	3.158	Up-regulation
CMGC_CDK_CDC2_CDK1_ST	P04637	TP53	P06493	CDK1	S33	P27S	27	Missense	distal	-6	no	3.447	3.446	EPSD	TCGA;ICGC;COSMIC	3.158	Down-regulation
CMGC_CDK_CDC2_CDK1_ST	P04637	TP53	P06493	CDK1	S33	P27L	27	Missense	distal	-6	no	3.447	3.474	EPSD	TCGA;ICGC;COSMIC;GDSC;CCLE	3.158	Up-regulation
CMGC_CDK_CDC2_CDK1_ST	P04637	TP53	P06493	CDK1	T81	A79V	79	Missense	proximal	-2	no	3.467	3.632	EPSD	TCGA;ICGC;COSMIC	3.158	Up-regulation
CMGC_CDK_CDC2_CDK1_ST	P04637	TP53	P06493	CDK1	T81	P77L	77	Missense	distal	-4	no	3.467	3.324	EPSD	TCGA;ICGC;COSMIC	3.158	Down-regulation
CMGC_CDK_CDC2_CDK1_ST	P04637	TP53	P06493	CDK1	T81	P82L	82	Missense	proximal	1	no	3.467	-0.219	EPSD	TCGA;ICGC;COSMIC	3.158	Loss
CMGC_CDK_CDC2_CDK1_ST	P04637	TP53	P06493	CDK1	T81	A74T	74	Missense	distal	-7	no	3.467	3.461	EPSD	TCGA;ICGC;COSMIC	3.158	Down-regulation
CMGC_CDK_CDC2_CDK1_ST	P04637	TP53	P06493	CDK1	T155	R156P	156	Missense	proximal	1	no	-0.359	3.250	EPSD	TCGA;ICGC;COSMIC;GDSC;CCLE	3.158	Gain
CMGC_CDK_CDC2_CDK1_ST	P30101	PDIA3	P06493	CDK1	S443	A438T	438	Missense	distal	-5	no	3.306	3.327	EPSD	TCGA;ICGC;COSMIC	3.158	Up-regulation
CMGC_CDK_CDC2_CDK1_ST	Q8NEB9	PIK3C3	P06493	CDK1	T159	S164I	164	Missense	distal	5	no	3.411	3.575	PhosphoSitePlus	TCGA;ICGC;COSMIC	3.158	Up-regulation
CMGC_CDK_CDC2_CDK1_ST	Q8NEB9	PIK3C3	P06493	CDK1	S448	S443F	443	Missense	distal	-5	no	3.168	3.278	EPSD	TCGA;ICGC;COSMIC	3.158	Up-regulation
CMGC_CDK_CDC2_CDK1_ST	Q8NEB9	PIK3C3	P06493	CDK1	S448	S442I	442	Missense	distal	-6	no	3.168	3.191	EPSD	TCGA;ICGC;COSMIC	3.158	Up-regulation
CMGC_CDK_CDC2_CDK1_ST	Q8NEB9	PIK3C3	P06493	CDK1	T668	E661A	661	Missense	distal	-7	no	3.601	3.696	EPSD	TCGA;COSMIC	3.158	Up-regulation
CMGC_CDK_CDC2_CDK1_ST	Q8NEB9	PIK3C3	P06493	CDK1	T668	T675I	675	Missense	distal	7	no	3.601	3.624	EPSD	TCGA	3.158	Up-regulation
CMGC_CDK_CDC2_CDK1_ST	Q8TD19	NEK9	P06493	CDK1	T214	E221Q	221	Missense	distal	7	no	3.620	3.610	EPSD	TCGA;ICGC;COSMIC	3.158	Down-regulation
CMGC_CDK_CDC2_CDK1_ST	Q8TD19	NEK9	P06493	CDK1	T358	Q360H	360	Missense	proximal	2	no	3.298	3.306	EPSD	TCGA;ICGC;COSMIC	3.158	Up-regulation
CMGC_CDK_CDC2_CDK1_ST	Q8TD19	NEK9	P06493	CDK1	T771	P774S	774	Missense	distal	3	no	3.249	3.300	EPSD	TCGA;ICGC;COSMIC	3.158	Up-regulation
CMGC_CDK_CDC2_CDK1_ST	Q8TD19	NEK9	P06493	CDK1	S793	M788I	788	Missense	distal	-5	no	3.343	3.417	EPSD	TCGA;ICGC;COSMIC	3.158	Up-regulation
CMGC_CDK_CDC2_CDK1_ST	Q8TD19	NEK9	P06493	CDK1	S829	P825H	825	Missense	distal	-4	no	3.256	3.237	EPSD	TCGA;ICGC	3.158	Down-regulation
CMGC_CDK_CDC2_CDK1_ST	Q8TD19	NEK9	P06493	CDK1	S829	L831V	831	Missense	proximal	2	no	3.256	3.250	EPSD	TCGA;ICGC;COSMIC	3.158	Down-regulation
CMGC_CDK_CDC2_CDK1_ST	Q8TD19	NEK9	P06493	CDK1	S829	S829Y	829	Missense	central	0	yes	3.256	0.000	EPSD	TCGA;ICGC;COSMIC	3.158	Loss
CMGC_CDK_CDC2_CDK1_ST	Q06481	APLP2	P06493	CDK1	T736	H741R	741	Missense	distal	5	no	3.591	3.526	PhosphoSitePlus	TCGA;COSMIC	3.158	Down-regulation
CMGC_CDK_CDC2_CDK1_ST	Q02952	AKAP12	P06493	CDK1	S253	S248I	248	Missense	distal	-5	no	3.108	3.238	EPSD	TCGA;COSMIC	3.158	Gain
CMGC_CDK_CDC2_CDK1_ST	Q02952	AKAP12	P06493	CDK1	S483	T477S	477	Missense	distal	-6	no	3.493	3.494	EPSD	TCGA;COSMIC	3.158	Up-regulation
CMGC_CDK_CDC2_CDK1_ST	Q02952	AKAP12	P06493	CDK1	S483	Q478R	478	Missense	distal	-5	no	3.493	3.525	EPSD	TCGA;COSMIC	3.158	Up-regulation
CMGC_CDK_CDC2_CDK1_ST	Q02952	AKAP12	P06493	CDK1	S514	R508S	508	Missense	distal	-6	no	3.926	3.919	EPSD	TCGA	3.158	Down-regulation
CMGC_CDK_CDC2_CDK1_ST	Q02952	AKAP12	P06493	CDK1	S743	P737T	737	Missense	distal	-6	no	3.622	3.619	EPSD	TCGA;COSMIC;CCLE	3.158	Down-regulation
CMGC_CDK_CDC2_CDK1_ST	Q02952	AKAP12	P06493	CDK1	S743	P750L	750	Missense	distal	7	no	3.622	3.650	EPSD	TCGA;COSMIC	3.158	Up-regulation
CMGC_CDK_CDC2_CDK1_ST	Q02952	AKAP12	P06493	CDK1	T767	R769I	769	Missense	proximal	2	no	3.239	3.253	PhosphoSitePlus	TCGA	3.158	Up-regulation
CMGC_CDK_CDC2_CDK1_ST	Q02952	AKAP12	P06493	CDK1	S1012	D1011G	1011	Missense	proximal	-1	no	3.194	3.329	EPSD	TCGA;COSMIC	3.158	Up-regulation
CMGC_CDK_CDC2_CDK1_ST	Q02952	AKAP12	P06493	CDK1	S1395	L1400P	1400	Missense	distal	5	no	3.393	3.208	EPSD	TCGA;COSMIC	3.158	Down-regulation
CMGC_CDK_CDC2_CDK1_ST	Q02952	AKAP12	P06493	CDK1	T1484	T1491I	1491	Missense	distal	7	no	3.209	3.232	EPSD	TCGA;COSMIC	3.158	Up-regulation
CMGC_CDK_CDC2_CDK1_ST	Q02952	AKAP12	P06493	CDK1	T1484	D1478N	1478	Missense	distal	-6	no	3.209	3.207	EPSD	TCGA;COSMIC	3.158	Down-regulation
CMGC_CDK_CDC2_CDK1_ST	Q02952	AKAP12	P06493	CDK1	T1484	S1483L	1483	Missense	proximal	-1	no	3.209	3.411	EPSD	TCGA;COSMIC	3.158	Up-regulation
CMGC_CDK_CDC2_CDK1_ST	Q02952	AKAP12	P06493	CDK1	S1727	T1724S	1724	Missense	distal	-3	no	3.563	3.558	EPSD	TCGA;COSMIC	3.158	Down-regulation
CMGC_CDK_CDC2_CDK1_ST	Q02952	AKAP12	P06493	CDK1	T1760	A1758V	1758	Missense	proximal	-2	no	3.158	3.324	EPSD	TCGA;COSMIC	3.158	Up-regulation
AGC_PKG_PRKG1_ST	P04792	HSPB1	Q13976-2	PRKG1	S15	L10H	10	Missense	distal	-5	no	10.333	10.159	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	7.092	Down-regulation
AGC_PKG_PRKG1_ST	P04792	HSPB1	Q13976-2	PRKG1	S78	L81I	81	Missense	distal	3	no	11.052	11.004	PhosphoSitePlus;EPSD	TCGA;ICGC;COSMIC	7.092	Down-regulation
AGC_PKG_PRKG1_ST	P04792	HSPB1	Q13976-2	PRKG1	T143	F138C	138	Missense	distal	-5	no	10.597	10.608	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	7.092	Up-regulation
AGC_PKG_PRKG1_ST	Q13976	PRKG1	Q13976-2	PRKG1	S27	E32D	32	Missense	distal	5	no	10.846	10.837	EPSD	TCGA;COSMIC	7.092	Down-regulation
AGC_PKG_PRKG1_ST	Q13976	PRKG1	Q13976-2	PRKG1	T59	P56T	56	Missense	distal	-3	no	8.128	7.864	EPSD	TCGA;COSMIC	7.092	Down-regulation
AGC_PKG_PRKG1_ST	Q13976	PRKG1	Q13976-2	PRKG1	S65	Q69H	69	Missense	distal	4	no	8.252	8.311	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	7.092	Up-regulation
AGC_PKG_PRKG1_ST	Q13153	PAK1	Q13976-2	PRKG1	S21	G27D	27	Missense	distal	6	no	8.946	9.035	PhosphoSitePlus	TCGA;ICGC;COSMIC	7.092	Up-regulation
AGC_PKG_PRKG1_ST	Q13153	PAK1	Q13976-2	PRKG1	S21	M23T	23	Missense	proximal	2	no	8.946	8.955	PhosphoSitePlus	TCGA;ICGC;COSMIC	7.092	Up-regulation
AGC_PKG_PRKG1_ST	Q13153	PAK1	Q13976-2	PRKG1	S21	A26V	26	Missense	distal	5	no	8.946	8.896	PhosphoSitePlus	TCGA;ICGC;COSMIC	7.092	Down-regulation
AGC_PKG_PRKG1_ST	Q13153	PAK1	Q13976-2	PRKG1	S21	S28N	28	Missense	distal	7	no	8.946	8.887	PhosphoSitePlus	TCGA;ICGC;COSMIC	7.092	Down-regulation
AGC_PKG_PRKG1_ST	Q13153	PAK1	Q13976-2	PRKG1	T271	D265Y	265	Missense	distal	-6	no	7.347	7.476	EPSD	TCGA;ICGC;COSMIC	7.092	Up-regulation
AGC_PKG_PRKG1_ST	Q13153	PAK1	Q13976-2	PRKG1	T271	G264C	264	Missense	distal	-7	no	7.347	7.069	EPSD	TCGA;ICGC;COSMIC	7.092	Loss
AGC_PKG_PRKG1_ST	Q13153	PAK1	Q13976-2	PRKG1	S422	E417Q	417	Missense	distal	-5	no	9.274	9.121	EPSD	TCGA;ICGC;COSMIC	7.092	Down-regulation
AGC_PKG_PRKG1_ST	Q13153	PAK1	Q13976-2	PRKG1	S422	R421L	421	Missense	proximal	-1	no	9.274	8.972	EPSD	TCGA;ICGC;COSMIC	7.092	Down-regulation
AGC_PKG_PRKG1_ST	Q13153	PAK1	Q13976-2	PRKG1	T423	E417Q	417	Missense	distal	-6	no	8.832	9.180	EPSD	TCGA;ICGC;COSMIC	7.092	Up-regulation
AGC_PKG_PRKG1_ST	Q13153	PAK1	Q13976-2	PRKG1	T423	R421L	421	Missense	proximal	-2	no	8.832	3.538	EPSD	TCGA;ICGC;COSMIC	7.092	Loss
AGC_PKG_PRKG1_ST	Q13153	PAK1	Q13976-2	PRKG1	S511	S511L	511	Missense	central	0	yes	10.380	0.000	EPSD	TCGA;ICGC;COSMIC	7.092	Loss
AGC_PKG_PRKG1_ST	Q14847	LASP1	Q13976-2	PRKG1	S61	V65L	65	Missense	distal	4	no	7.442	7.534	EPSD	TCGA;ICGC;COSMIC	7.092	Up-regulation
AGC_PKG_PRKG1_ST	Q14847	LASP1	Q13976-2	PRKG1	S61	A55V	55	Missense	distal	-6	no	7.442	7.106	EPSD	TCGA;COSMIC	7.092	Down-regulation
AGC_PKG_PRKG1_ST	Q14847	LASP1	Q13976-2	PRKG1	S99	P105S	105	Missense	distal	6	no	7.566	7.331	EPSD	TCGA;ICGC;COSMIC	7.092	Down-regulation
AGC_PKG_PRKG1_ST	Q14847	LASP1	Q13976-2	PRKG1	S146	M139V	139	Missense	distal	-7	no	12.899	12.293	PhosphoSitePlus	TCGA;ICGC;COSMIC	7.092	Down-regulation
STE_STE20_PAKB_PAK4_ST	O43623	SNAI2	O96013	PAK4	S100	K97M	97	Missense	distal	-3	no	17.763	15.110	EPSD	TCGA;ICGC;COSMIC	14.946	Down-regulation
STE_STE20_PAKB_PAK4_ST	O43623	SNAI2	O96013	PAK4	S100	D98Y	98	Missense	proximal	-2	no	17.763	20.610	EPSD	TCGA;ICGC;COSMIC	14.946	Up-regulation
STE_STE20_PAKB_PAK4_ST	O43623	SNAI2	O96013	PAK4	S158	S158Y	158	Missense	central	0	yes	19.917	0.000	PhosphoSitePlus	TCGA;ICGC;COSMIC	14.946	Loss
STE_STE20_PAKB_PAK4_ST	O43623	SNAI2	O96013	PAK4	S158	D152N	152	Missense	distal	-6	no	19.917	19.902	PhosphoSitePlus	TCGA	14.946	Down-regulation
STE_STE20_PAKB_PAK4_ST	O43623	SNAI2	O96013	PAK4	S158	C151W	151	Missense	distal	-7	no	19.917	21.369	PhosphoSitePlus	TCGA;ICGC;COSMIC	14.946	Up-regulation
STE_STE20_PAKB_PAK4_ST	O43623	SNAI2	O96013	PAK4	S158	C161Y	161	Missense	distal	3	no	19.917	19.424	PhosphoSitePlus	TCGA;ICGC;COSMIC	14.946	Down-regulation
STE_STE20_PAKB_PAK4_ST	O43623	SNAI2	O96013	PAK4	S170	K166N	166	Missense	distal	-4	no	15.232	14.016	EPSD	TCGA;ICGC;COSMIC	14.946	Loss
STE_STE20_PAKB_PAK4_ST	O43623	SNAI2	O96013	PAK4	S170	A173T	173	Missense	distal	3	no	15.232	14.598	EPSD	TCGA;ICGC;COSMIC;GDSC;CCLE	14.946	Loss
STE_STE20_PAKB_PAK4_ST	O43623	SNAI2	O96013	PAK4	S170	K175E	175	Missense	distal	5	no	15.232	15.131	EPSD	TCGA;ICGC;COSMIC	14.946	Down-regulation
STE_STE20_PAKB_PAK4_ST	O43623	SNAI2	O96013	PAK4	S247	F250L	250	Missense	distal	3	no	15.232	15.491	EPSD	TCGA;ICGC	14.946	Up-regulation
STE_STE20_PAKB_PAK4_ST	O43623	SNAI2	O96013	PAK4	S247	S247F	247	Missense	central	0	yes	15.232	0.000	EPSD	TCGA	14.946	Loss
STE_STE20_PAKB_PAK4_ST	O43623	SNAI2	O96013	PAK4	S247	T249P	249	Missense	proximal	2	no	15.232	15.508	EPSD	TCGA;ICGC;COSMIC	14.946	Up-regulation
STE_STE20_PAKB_PAK4_ST	O43623	SNAI2	O96013	PAK4	S251	F250L	250	Missense	proximal	-1	no	18.576	17.603	EPSD	TCGA;ICGC	14.946	Down-regulation
STE_STE20_PAKB_PAK4_ST	O43623	SNAI2	O96013	PAK4	S251	S247F	247	Missense	distal	-4	no	18.576	16.966	EPSD	TCGA	14.946	Down-regulation
STE_STE20_PAKB_PAK4_ST	O43623	SNAI2	O96013	PAK4	S251	T249P	249	Missense	proximal	-2	no	18.576	18.542	EPSD	TCGA;ICGC;COSMIC	14.946	Down-regulation
STE_STE20_PAKB_PAK4_ST	O96013	PAK4	O96013	PAK4	S97	T95I	95	Missense	proximal	-2	no	13.582	15.417	EPSD	TCGA;ICGC;COSMIC	14.946	Gain
STE_STE20_PAKB_PAK4_ST	O96013	PAK4	O96013	PAK4	S99	T95I	95	Missense	distal	-4	no	17.891	17.153	EPSD	TCGA;ICGC;COSMIC	14.946	Down-regulation
STE_STE20_PAKB_PAK4_ST	O96013	PAK4	O96013	PAK4	S104	R110H	110	Missense	distal	6	no	16.271	16.569	EPSD	TCGA;ICGC;COSMIC	14.946	Up-regulation
STE_STE20_PAKB_PAK4_ST	O96013	PAK4	O96013	PAK4	S142	E143D	143	Missense	proximal	1	no	15.389	15.259	EPSD	TCGA;ICGC;COSMIC	14.946	Down-regulation
STE_STE20_PAKB_PAK4_ST	O96013	PAK4	O96013	PAK4	S142	F138S	138	Missense	distal	-4	no	15.389	16.999	EPSD	TCGA;ICGC	14.946	Up-regulation
STE_STE20_PAKB_PAK4_ST	O96013	PAK4	O96013	PAK4	S217	R218W	218	Missense	proximal	1	no	15.691	14.736	EPSD	TCGA;ICGC;COSMIC	14.946	Loss
STE_STE20_PAKB_PAK4_ST	O96013	PAK4	O96013	PAK4	S246	S246F	246	Missense	central	0	yes	15.674	0.000	EPSD	TCGA;ICGC;COSMIC	14.946	Loss
STE_STE20_PAKB_PAK4_ST	O96013	PAK4	O96013	PAK4	S246	Q241H	241	Missense	distal	-5	no	15.674	15.844	EPSD	TCGA;ICGC;COSMIC	14.946	Up-regulation
STE_STE20_PAKB_PAK4_ST	O96013	PAK4	O96013	PAK4	S247	R254Q	254	Missense	distal	7	no	16.474	16.510	EPSD	TCGA;ICGC;COSMIC	14.946	Up-regulation
STE_STE20_PAKB_PAK4_ST	O96013	PAK4	O96013	PAK4	S247	S246F	246	Missense	proximal	-1	no	16.474	16.299	EPSD	TCGA;ICGC;COSMIC	14.946	Down-regulation
STE_STE20_PAKB_PAK4_ST	O96013	PAK4	O96013	PAK4	S247	Q241H	241	Missense	distal	-6	no	16.474	16.484	EPSD	TCGA;ICGC;COSMIC	14.946	Up-regulation
STE_STE20_PAKB_PAK4_ST	O96013	PAK4	O96013	PAK4	S445	D444N	444	Missense	proximal	-1	no	15.715	15.974	EPSD	TCGA;ICGC	14.946	Up-regulation
STE_STE20_PAKB_PAK4_ST	O96013	PAK4	O96013	PAK4	S445	H450R	450	Missense	distal	5	no	15.715	15.887	EPSD	TCGA;ICGC	14.946	Up-regulation
STE_STE20_PAKB_PAK4_ST	O96013	PAK4	O96013	PAK4	S474	P479L	479	Missense	distal	5	no	31.770	31.511	PhosphoSitePlus	TCGA;ICGC;COSMIC	14.946	Down-regulation
STE_STE20_PAKB_PAK4_ST	O96013	PAK4	O96013	PAK4	S474	T478M	478	Missense	distal	4	no	31.770	31.717	PhosphoSitePlus	TCGA;ICGC;COSMIC	14.946	Down-regulation
STE_STE20_PAKB_PAK4_ST	O96013	PAK4	O96013	PAK4	S474	S474L	474	Missense	central	0	yes	31.770	0.000	PhosphoSitePlus	TCGA;ICGC;COSMIC;GDSC;CCLE	14.946	Loss
STE_STE20_PAKB_PAK4_ST	P35222	CTNNB1	O96013	PAK4	S37	G34R	34	Missense	distal	-3	no	15.702	21.949	EPSD	TCGA;COSMIC	14.946	Up-regulation
STE_STE20_PAKB_PAK4_ST	P35222	CTNNB1	O96013	PAK4	S37	G34V	34	Missense	distal	-3	no	15.702	13.885	EPSD	TCGA;COSMIC;CCLE	14.946	Loss
STE_STE20_PAKB_PAK4_ST	P35222	CTNNB1	O96013	PAK4	S37	T41A	41	Missense	distal	4	no	15.702	15.722	EPSD	TCGA;COSMIC;GDSC;CCLE	14.946	Up-regulation
STE_STE20_PAKB_PAK4_ST	P35222	CTNNB1	O96013	PAK4	S37	G34E	34	Missense	distal	-3	no	15.702	15.982	EPSD	TCGA;COSMIC;GDSC;CCLE	14.946	Up-regulation
STE_STE20_PAKB_PAK4_ST	P35222	CTNNB1	O96013	PAK4	S37	S37C	37	Missense	central	0	yes	15.702	0.000	EPSD	TCGA;COSMIC;GDSC;CCLE	14.946	Loss
STE_STE20_PAKB_PAK4_ST	P35222	CTNNB1	O96013	PAK4	S37	S37F	37	Missense	central	0	yes	15.702	0.000	EPSD	TCGA;COSMIC;GDSC;CCLE	14.946	Loss
STE_STE20_PAKB_PAK4_ST	P35222	CTNNB1	O96013	PAK4	S37	S33F	33	Missense	distal	-4	no	15.702	14.092	EPSD	TCGA;COSMIC;GDSC;CCLE	14.946	Loss
STE_STE20_PAKB_PAK4_ST	P35222	CTNNB1	O96013	PAK4	S37	D32H	32	Missense	distal	-5	no	15.702	15.933	EPSD	TCGA;COSMIC	14.946	Up-regulation
STE_STE20_PAKB_PAK4_ST	P35222	CTNNB1	O96013	PAK4	S37	D32G	32	Missense	distal	-5	no	15.702	15.551	EPSD	TCGA;COSMIC	14.946	Down-regulation
STE_STE20_PAKB_PAK4_ST	P35222	CTNNB1	O96013	PAK4	S37	T41I	41	Missense	distal	4	no	15.702	15.928	EPSD	TCGA;COSMIC	14.946	Up-regulation
STE_STE20_PAKB_PAK4_ST	P35222	CTNNB1	O96013	PAK4	S37	S33A	33	Missense	distal	-4	no	15.702	15.505	EPSD	TCGA;COSMIC	14.946	Down-regulation
STE_STE20_PAKB_PAK4_ST	P35222	CTNNB1	O96013	PAK4	S37	S33Y	33	Missense	distal	-4	no	15.702	14.096	EPSD	TCGA;COSMIC;GDSC;CCLE	14.946	Loss
STE_STE20_PAKB_PAK4_ST	P35222	CTNNB1	O96013	PAK4	S37	D32V	32	Missense	distal	-5	no	15.702	15.347	EPSD	TCGA;COSMIC;CCLE	14.946	Down-regulation
STE_STE20_PAKB_PAK4_ST	P35222	CTNNB1	O96013	PAK4	S37	S33P	33	Missense	distal	-4	no	15.702	15.058	EPSD	TCGA;COSMIC;CCLE	14.946	Down-regulation
STE_STE20_PAKB_PAK4_ST	P35222	CTNNB1	O96013	PAK4	S37	H36P	36	Missense	proximal	-1	no	15.702	13.673	EPSD	TCGA;COSMIC;CCLE	14.946	Loss
STE_STE20_PAKB_PAK4_ST	P35222	CTNNB1	O96013	PAK4	S37	D32Y	32	Missense	distal	-5	no	15.702	16.028	EPSD	TCGA;COSMIC;CCLE	14.946	Up-regulation
STE_STE20_PAKB_PAK4_ST	P35222	CTNNB1	O96013	PAK4	S37	I35S	35	Missense	proximal	-2	no	15.702	16.358	EPSD	TCGA;COSMIC	14.946	Up-regulation
STE_STE20_PAKB_PAK4_ST	P35222	CTNNB1	O96013	PAK4	S37	S37Y	37	Missense	central	0	yes	15.702	0.000	EPSD	TCGA;COSMIC	14.946	Loss
STE_STE20_PAKB_PAK4_ST	P35222	CTNNB1	O96013	PAK4	S37	S33C	33	Missense	distal	-4	no	15.702	13.501	EPSD	TCGA;COSMIC;GDSC;CCLE	14.946	Loss
STE_STE20_PAKB_PAK4_ST	P35222	CTNNB1	O96013	PAK4	S37	S37A	37	Missense	central	0	yes	15.702	0.000	EPSD	TCGA;COSMIC;GDSC;CCLE	14.946	Loss
STE_STE20_PAKB_PAK4_ST	P35222	CTNNB1	O96013	PAK4	S37	D32N	32	Missense	distal	-5	no	15.702	15.756	EPSD	TCGA;COSMIC;CCLE	14.946	Up-regulation
STE_STE20_PAKB_PAK4_ST	P35222	CTNNB1	O96013	PAK4	S37	S33T	33	Missense	distal	-4	no	15.702	14.455	EPSD	TCGA;COSMIC	14.946	Loss
STE_STE20_PAKB_PAK4_ST	P35222	CTNNB1	O96013	PAK4	S37	T41N	41	Missense	distal	4	no	15.702	15.849	EPSD	TCGA;COSMIC	14.946	Up-regulation
STE_STE20_PAKB_PAK4_ST	P35222	CTNNB1	O96013	PAK4	S37	S37P	37	Missense	central	0	yes	15.702	0.000	EPSD	TCGA;COSMIC;GDSC;CCLE	14.946	Loss
STE_STE20_PAKB_PAK4_ST	P35222	CTNNB1	O96013	PAK4	S37	D32A	32	Missense	distal	-5	no	15.702	15.825	EPSD	TCGA;COSMIC	14.946	Up-regulation
STE_STE20_PAKB_PAK4_ST	P35222	CTNNB1	O96013	PAK4	S184	R185G	185	Missense	proximal	1	no	18.116	17.063	EPSD	TCGA;COSMIC	14.946	Down-regulation
STE_STE20_PAKB_PAK4_ST	P35222	CTNNB1	O96013	PAK4	S552	M553V	553	Missense	proximal	1	no	19.614	18.748	EPSD	TCGA;COSMIC	14.946	Down-regulation
STE_STE20_PAKB_PAK4_ST	P35222	CTNNB1	O96013	PAK4	S675	S681F	681	Missense	distal	6	no	29.056	29.182	PhosphoSitePlus	TCGA	14.946	Up-regulation
STE_STE20_PAKB_PAK4_ST	P35222	CTNNB1	O96013	PAK4	S721	P714R	714	Missense	distal	-7	no	13.589	15.412	EPSD	TCGA;COSMIC	14.946	Gain
STE_STE20_PAKB_PAK4_ST	O00401	WASL	O96013	PAK4	S62	S58L	58	Missense	distal	-4	no	18.080	14.989	EPSD	TCGA;ICGC;COSMIC	14.946	Down-regulation
STE_STE20_PAKB_PAK4_ST	O00401	WASL	O96013	PAK4	S479	A481G	481	Missense	proximal	2	no	18.096	17.473	EPSD	TCGA;ICGC	14.946	Down-regulation
STE_STE20_PAKB_PAK4_ST	O00401	WASL	O96013	PAK4	S484	A481G	481	Missense	distal	-3	no	24.018	22.053	PhosphoSitePlus;EPSD	TCGA;ICGC	14.946	Down-regulation
STE_STE20_PAKB_PAK4_ST	O00401	WASL	O96013	PAK4	S485	A481G	481	Missense	distal	-4	no	25.842	25.046	EPSD;PhosphoSitePlus	TCGA;ICGC	14.946	Down-regulation
STE_STE20_PAKB_PAK4_ST	O00401	WASL	O96013	PAK4	S485	D492N	492	Missense	distal	7	no	25.842	25.808	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	14.946	Down-regulation
STE_STE20_PAKB_PAK4_ST	P18084	ITGB5	O96013	PAK4	S149	M144T	144	Missense	distal	-5	no	16.176	15.579	EPSD	TCGA;ICGC;COSMIC	14.946	Down-regulation
STE_STE20_PAKB_PAK4_ST	P18084	ITGB5	O96013	PAK4	S149	D155G	155	Missense	distal	6	no	16.176	16.242	EPSD	TCGA;ICGC;COSMIC	14.946	Up-regulation
STE_STE20_PAKB_PAK4_ST	P18084	ITGB5	O96013	PAK4	S759	K756N	756	Missense	distal	-3	no	26.078	20.241	PhosphoSitePlus;EPSD	TCGA;ICGC	14.946	Down-regulation
STE_STE20_PAKB_PAK4_ST	P18084	ITGB5	O96013	PAK4	S759	A764V	764	Missense	distal	5	no	26.078	25.947	PhosphoSitePlus;EPSD	TCGA;ICGC;COSMIC	14.946	Down-regulation
STE_STE20_PAKB_PAK4_ST	P18084	ITGB5	O96013	PAK4	S762	K756N	756	Missense	distal	-6	no	23.858	23.616	EPSD;PhosphoSitePlus	TCGA;ICGC	14.946	Down-regulation
STE_STE20_PAKB_PAK4_ST	P18084	ITGB5	O96013	PAK4	S762	A764V	764	Missense	proximal	2	no	23.858	23.351	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	14.946	Down-regulation
STE_STE20_PAKB_PAK4_ST	P18084	ITGB5	O96013	PAK4	S770	K776T	776	Missense	distal	6	no	18.652	18.771	EPSD	TCGA;ICGC;COSMIC	14.946	Up-regulation
STE_STE20_PAKB_PAK4_ST	P18084	ITGB5	O96013	PAK4	S770	N771T	771	Missense	proximal	1	no	18.652	18.052	EPSD	TCGA;ICGC;COSMIC	14.946	Down-regulation
STE_STE20_PAKB_PAK4_ST	P18084	ITGB5	O96013	PAK4	S770	P777S	777	Missense	distal	7	no	18.652	18.347	EPSD	TCGA;ICGC;COSMIC	14.946	Down-regulation
STE_STE20_PAKB_PAK4_ST	P18084	ITGB5	O96013	PAK4	S770	P777H	777	Missense	distal	7	no	18.652	18.418	EPSD	TCGA;ICGC	14.946	Down-regulation
STE_STE20_PAKB_PAK4_ST	P18084	ITGB5	O96013	PAK4	S770	A764V	764	Missense	distal	-6	no	18.652	18.447	EPSD	TCGA;ICGC;COSMIC	14.946	Down-regulation
STE_STE20_PAKB_PAK4_ST	P18084	ITGB5	O96013	PAK4	S779	P777S	777	Missense	proximal	-2	no	13.502	16.027	EPSD	TCGA;ICGC;COSMIC	14.946	Gain
STE_STE20_PAKB_PAK4_ST	P18084	ITGB5	O96013	PAK4	S779	P777H	777	Missense	proximal	-2	no	13.502	17.982	EPSD	TCGA;ICGC	14.946	Gain
STE_STE20_PAKB_PAK4_ST	P49023	PXN	O96013	PAK4	S126	E128K	128	Missense	proximal	2	no	17.058	16.205	EPSD	TCGA;COSMIC	14.946	Down-regulation
STE_STE20_PAKB_PAK4_ST	P49023	PXN	O96013	PAK4	S126	Q124H	124	Missense	proximal	-2	no	17.058	20.396	EPSD	TCGA;COSMIC	14.946	Up-regulation
STE_STE20_PAKB_PAK4_ST	P49023	PXN	O96013	PAK4	S272	E268K	268	Missense	distal	-4	no	23.039	23.043	PhosphoSitePlus	TCGA;COSMIC	14.946	Up-regulation
STE_STE20_PAKB_PAK4_ST	P49023	PXN	O96013	PAK4	S272	S274L	274	Missense	proximal	2	no	23.039	20.646	PhosphoSitePlus	TCGA;COSMIC	14.946	Down-regulation
STE_STE20_PAKB_PAK4_ST	Q92974	ARHGEF2	O96013	PAK4	S122	P120L	120	Missense	proximal	-2	no	18.495	18.072	EPSD	TCGA;COSMIC	14.946	Down-regulation
STE_STE20_PAKB_PAK4_ST	Q92974	ARHGEF2	O96013	PAK4	S122	P126S	126	Missense	distal	4	no	18.495	18.408	EPSD	TCGA;COSMIC	14.946	Down-regulation
STE_STE20_PAKB_PAK4_ST	Q92974	ARHGEF2	O96013	PAK4	S122	R117Q	117	Missense	distal	-5	no	18.495	17.839	EPSD	TCGA;COSMIC	14.946	Down-regulation
STE_STE20_PAKB_PAK4_ST	Q92974	ARHGEF2	O96013	PAK4	S133	R139H	139	Missense	distal	6	no	16.653	16.951	EPSD	TCGA;ICGC;COSMIC	14.946	Up-regulation
STE_STE20_PAKB_PAK4_ST	Q92974	ARHGEF2	O96013	PAK4	S133	P126S	126	Missense	distal	-7	no	16.653	16.265	EPSD	TCGA;COSMIC	14.946	Down-regulation
STE_STE20_PAKB_PAK4_ST	Q92974	ARHGEF2	O96013	PAK4	S133	S133F	133	Missense	central	0	yes	16.653	0.000	EPSD	TCGA;COSMIC	14.946	Loss
STE_STE20_PAKB_PAK4_ST	Q92974	ARHGEF2	O96013	PAK4	S142	R139H	139	Missense	distal	-3	no	17.668	13.662	EPSD	TCGA;ICGC;COSMIC	14.946	Loss
STE_STE20_PAKB_PAK4_ST	Q92974	ARHGEF2	O96013	PAK4	S143	R139H	139	Missense	distal	-4	no	23.198	22.726	EPSD	TCGA;ICGC;COSMIC	14.946	Down-regulation
STE_STE20_PAKB_PAK4_ST	Q92974	ARHGEF2	O96013	PAK4	S186	R183Q	183	Missense	distal	-3	no	15.369	9.845	EPSD	TCGA;COSMIC	14.946	Loss
STE_STE20_PAKB_PAK4_ST	Q92974	ARHGEF2	O96013	PAK4	S186	T184I	184	Missense	proximal	-2	no	15.369	17.204	EPSD	TCGA;COSMIC	14.946	Up-regulation
STE_STE20_PAKB_PAK4_ST	Q92974	ARHGEF2	O96013	PAK4	S645	R650C	650	Missense	distal	5	no	19.060	18.752	EPSD	TCGA;COSMIC;CCLE	14.946	Down-regulation
STE_STE20_PAKB_PAK4_ST	Q92974	ARHGEF2	O96013	PAK4	S645	L640V	640	Missense	distal	-5	no	19.060	18.980	EPSD	TCGA;COSMIC	14.946	Down-regulation
STE_STE20_PAKB_PAK4_ST	Q92974	ARHGEF2	O96013	PAK4	S645	R638S	638	Missense	distal	-7	no	19.060	16.849	EPSD	TCGA;COSMIC	14.946	Down-regulation
STE_STE20_PAKB_PAK4_ST	Q92974	ARHGEF2	O96013	PAK4	S733	P734L	734	Missense	proximal	1	no	13.721	16.594	EPSD	TCGA	14.946	Gain
STE_STE20_PAKB_PAK4_ST	Q92974	ARHGEF2	O96013	PAK4	S782	R783W	783	Missense	proximal	1	no	18.870	17.915	EPSD	TCGA;COSMIC	14.946	Down-regulation
STE_STE20_PAKB_PAK4_ST	Q92974	ARHGEF2	O96013	PAK4	S886	A889T	889	Missense	distal	3	no	32.303	31.670	EPSD	TCGA;COSMIC	14.946	Down-regulation
STE_STE20_PAKB_PAK4_ST	Q92974	ARHGEF2	O96013	PAK4	S886	D891N	891	Missense	distal	5	no	32.303	32.250	EPSD	TCGA;COSMIC	14.946	Down-regulation
STE_STE20_PAKB_PAK4_ST	Q92974	ARHGEF2	O96013	PAK4	S886	R885H	885	Missense	proximal	-1	no	32.303	29.924	EPSD	TCGA;COSMIC	14.946	Down-regulation
STE_STE20_PAKB_PAK4_ST	Q92974	ARHGEF2	O96013	PAK4	S886	R883W	883	Missense	distal	-3	no	32.303	25.378	EPSD	TCGA;COSMIC	14.946	Down-regulation
STE_STE20_PAKB_PAK4_ST	Q92974	ARHGEF2	O96013	PAK4	S896	S896R	896	Missense	central	0	yes	24.927	0.000	EPSD	TCGA;COSMIC	14.946	Loss
STE_STE20_PAKB_PAK4_ST	Q92974	ARHGEF2	O96013	PAK4	S896	A889T	889	Missense	distal	-7	no	24.927	23.613	EPSD	TCGA;COSMIC	14.946	Down-regulation
STE_STE20_PAKB_PAK4_ST	Q92974	ARHGEF2	O96013	PAK4	S896	D891N	891	Missense	distal	-5	no	24.927	24.981	EPSD	TCGA;COSMIC	14.946	Up-regulation
STE_STE20_PAKB_PAK4_ST	Q92974	ARHGEF2	O96013	PAK4	S956	S953R	953	Missense	distal	-3	no	13.458	18.786	EPSD	TCGA;COSMIC	14.946	Gain
STE_STE20_PAKB_PAK4_ST	P62826	RAN	O96013	PAK4	S135	R140Q	140	Missense	distal	5	no	27.598	27.490	PhosphoSitePlus	TCGA;COSMIC	14.946	Down-regulation
STE_STE20_PAKB_PAK4_ST	P04637	TP53	O96013	PAK4	S46	D48N	48	Missense	proximal	2	no	16.273	16.431	EPSD	TCGA;ICGC;COSMIC;GDSC;CCLE	14.946	Up-regulation
STE_STE20_PAKB_PAK4_ST	P04637	TP53	O96013	PAK4	S106	G105R	105	Missense	proximal	-1	no	13.479	17.425	EPSD	TCGA;ICGC;COSMIC;CCLE	14.946	Gain
STE_STE20_PAKB_PAK4_ST	P04637	TP53	O96013	PAK4	S106	G105S	105	Missense	proximal	-1	no	13.479	15.277	EPSD	TCGA;ICGC;COSMIC	14.946	Gain
STE_STE20_PAKB_PAK4_ST	P04637	TP53	O96013	PAK4	S183	H179R	179	Missense	distal	-4	no	14.982	15.453	EPSD	TCGA;ICGC;COSMIC;GDSC;CCLE	14.946	Up-regulation
STE_STE20_PAKB_PAK4_ST	P04637	TP53	O96013	PAK4	S183	C176F	176	Missense	distal	-7	no	14.982	16.570	EPSD	TCGA;ICGC;COSMIC;GDSC;CCLE	14.946	Up-regulation
STE_STE20_PAKB_PAK4_ST	P04637	TP53	O96013	PAK4	S183	R181H	181	Missense	proximal	-2	no	14.982	13.692	EPSD	TCGA;ICGC;COSMIC;CCLE	14.946	Loss
STE_STE20_PAKB_PAK4_ST	P04637	TP53	O96013	PAK4	S183	G187S	187	Missense	distal	4	no	14.982	14.795	EPSD	TCGA;ICGC;COSMIC	14.946	Loss
STE_STE20_PAKB_PAK4_ST	P04637	TP53	O96013	PAK4	S183	H179Y	179	Missense	distal	-4	no	14.982	14.338	EPSD	TCGA;ICGC;COSMIC	14.946	Loss
STE_STE20_PAKB_PAK4_ST	P04637	TP53	O96013	PAK4	S183	C176Y	176	Missense	distal	-7	no	14.982	16.522	EPSD	TCGA;ICGC;COSMIC;GDSC;CCLE	14.946	Up-regulation
STE_STE20_PAKB_PAK4_ST	P04637	TP53	O96013	PAK4	S183	P190L	190	Missense	distal	7	no	14.982	15.048	EPSD	TCGA;ICGC;COSMIC;CCLE	14.946	Up-regulation
STE_STE20_PAKB_PAK4_ST	P04637	TP53	O96013	PAK4	S183	P177S	177	Missense	distal	-6	no	14.982	15.090	EPSD	TCGA;ICGC;COSMIC	14.946	Up-regulation
STE_STE20_PAKB_PAK4_ST	P04637	TP53	O96013	PAK4	S183	H178Q	178	Missense	distal	-5	no	14.982	14.812	EPSD	TCGA;ICGC;COSMIC	14.946	Loss
STE_STE20_PAKB_PAK4_ST	P04637	TP53	O96013	PAK4	S183	E180K	180	Missense	distal	-3	no	14.982	20.934	EPSD	TCGA;ICGC;COSMIC;CCLE	14.946	Up-regulation
STE_STE20_PAKB_PAK4_ST	P04637	TP53	O96013	PAK4	S183	C176S	176	Missense	distal	-7	no	14.982	17.468	EPSD	TCGA;ICGC;COSMIC;GDSC;CCLE	14.946	Up-regulation
STE_STE20_PAKB_PAK4_ST	P04637	TP53	O96013	PAK4	S183	H179N	179	Missense	distal	-4	no	14.982	14.444	EPSD	TCGA;ICGC;COSMIC	14.946	Loss
STE_STE20_PAKB_PAK4_ST	P04637	TP53	O96013	PAK4	S183	H179P	179	Missense	distal	-4	no	14.982	15.300	EPSD	TCGA;ICGC;COSMIC	14.946	Up-regulation
STE_STE20_PAKB_PAK4_ST	P04637	TP53	O96013	PAK4	S183	H179L	179	Missense	distal	-4	no	14.982	12.853	EPSD	TCGA;ICGC;COSMIC	14.946	Loss
STE_STE20_PAKB_PAK4_ST	P04637	TP53	O96013	PAK4	S183	H179D	179	Missense	distal	-4	no	14.982	14.863	EPSD	TCGA;ICGC;COSMIC;GDSC;CCLE	14.946	Loss
STE_STE20_PAKB_PAK4_ST	P04637	TP53	O96013	PAK4	S183	P190R	190	Missense	distal	7	no	14.982	14.658	EPSD	TCGA;ICGC;COSMIC	14.946	Loss
STE_STE20_PAKB_PAK4_ST	P04637	TP53	O96013	PAK4	S183	P177R	177	Missense	distal	-6	no	14.982	15.201	EPSD	TCGA;ICGC;COSMIC	14.946	Up-regulation
STE_STE20_PAKB_PAK4_ST	P04637	TP53	O96013	PAK4	S183	P177H	177	Missense	distal	-6	no	14.982	15.032	EPSD	TCGA;ICGC;COSMIC	14.946	Up-regulation
STE_STE20_PAKB_PAK4_ST	P04637	TP53	O96013	PAK4	S183	C176W	176	Missense	distal	-7	no	14.982	16.434	EPSD	TCGA;ICGC;COSMIC;GDSC;CCLE	14.946	Up-regulation
STE_STE20_PAKB_PAK4_ST	P04637	TP53	O96013	PAK4	S183	H179Q	179	Missense	distal	-4	no	14.982	15.057	EPSD	TCGA;ICGC;COSMIC;GDSC;CCLE	14.946	Up-regulation
STE_STE20_PAKB_PAK4_ST	P04637	TP53	O96013	PAK4	S183	P177T	177	Missense	distal	-6	no	14.982	14.956	EPSD	TCGA;ICGC;COSMIC;GDSC;CCLE	14.946	Down-regulation
STE_STE20_PAKB_PAK4_ST	P04637	TP53	O96013	PAK4	S183	R181P	181	Missense	proximal	-2	no	14.982	9.212	EPSD	TCGA;ICGC;COSMIC;CCLE	14.946	Loss
STE_STE20_PAKB_PAK4_ST	P04637	TP53	O96013	PAK4	S183	C176R	176	Missense	distal	-7	no	14.982	19.679	EPSD	TCGA;ICGC;COSMIC	14.946	Up-regulation
STE_STE20_PAKB_PAK4_ST	P04637	TP53	O96013	PAK4	S183	R181C	181	Missense	proximal	-2	no	14.982	9.195	EPSD	TCGA;ICGC;COSMIC;GDSC;CCLE	14.946	Loss
STE_STE20_PAKB_PAK4_ST	P04637	TP53	O96013	PAK4	S183	P177L	177	Missense	distal	-6	no	14.982	14.847	EPSD	TCGA;ICGC;COSMIC;GDSC;CCLE	14.946	Loss
STE_STE20_PAKB_PAK4_ST	P04637	TP53	O96013	PAK4	S215	Y220C	220	Missense	distal	5	no	24.434	24.334	PhosphoSitePlus	TCGA;ICGC;COSMIC;GDSC;CCLE	14.946	Down-regulation
STE_STE20_PAKB_PAK4_ST	P04637	TP53	O96013	PAK4	S215	R213Q	213	Missense	proximal	-2	no	24.434	19.807	PhosphoSitePlus	TCGA;ICGC;COSMIC;GDSC;CCLE	14.946	Down-regulation
STE_STE20_PAKB_PAK4_ST	P04637	TP53	O96013	PAK4	S215	D208N	208	Missense	distal	-7	no	24.434	22.982	PhosphoSitePlus	TCGA;ICGC;COSMIC	14.946	Down-regulation
STE_STE20_PAKB_PAK4_ST	P04637	TP53	O96013	PAK4	S215	H214R	214	Missense	proximal	-1	no	24.434	26.814	PhosphoSitePlus	TCGA;ICGC;COSMIC;GDSC;CCLE	14.946	Up-regulation
STE_STE20_PAKB_PAK4_ST	P04637	TP53	O96013	PAK4	S215	V218E	218	Missense	distal	3	no	24.434	23.835	PhosphoSitePlus	TCGA;ICGC;COSMIC	14.946	Down-regulation
STE_STE20_PAKB_PAK4_ST	P04637	TP53	O96013	PAK4	S215	Y220H	220	Missense	distal	5	no	24.434	24.471	PhosphoSitePlus	TCGA;ICGC;COSMIC	14.946	Up-regulation
STE_STE20_PAKB_PAK4_ST	P04637	TP53	O96013	PAK4	S215	S215I	215	Missense	central	0	yes	24.434	0.000	PhosphoSitePlus	TCGA;ICGC;COSMIC;GDSC;CCLE	14.946	Loss
STE_STE20_PAKB_PAK4_ST	P04637	TP53	O96013	PAK4	S215	V216M	216	Missense	proximal	1	no	24.434	25.300	PhosphoSitePlus	TCGA;ICGC;COSMIC;GDSC;CCLE	14.946	Up-regulation
STE_STE20_PAKB_PAK4_ST	P04637	TP53	O96013	PAK4	S215	Y220S	220	Missense	distal	5	no	24.434	24.538	PhosphoSitePlus	TCGA;ICGC;COSMIC	14.946	Up-regulation
STE_STE20_PAKB_PAK4_ST	P04637	TP53	O96013	PAK4	S215	S215N	215	Missense	central	0	yes	24.434	0.000	PhosphoSitePlus	TCGA;ICGC;COSMIC;GDSC;CCLE	14.946	Loss
STE_STE20_PAKB_PAK4_ST	P04637	TP53	O96013	PAK4	S215	T211I	211	Missense	distal	-4	no	24.434	23.697	PhosphoSitePlus	TCGA;ICGC;COSMIC;CCLE	14.946	Down-regulation
STE_STE20_PAKB_PAK4_ST	P04637	TP53	O96013	PAK4	S215	V216G	216	Missense	proximal	1	no	24.434	24.087	PhosphoSitePlus	TCGA;ICGC;COSMIC	14.946	Down-regulation
STE_STE20_PAKB_PAK4_ST	P04637	TP53	O96013	PAK4	S215	R213L	213	Missense	proximal	-2	no	24.434	18.242	PhosphoSitePlus	TCGA;ICGC;COSMIC;GDSC;CCLE	14.946	Down-regulation
STE_STE20_PAKB_PAK4_ST	P04637	TP53	O96013	PAK4	S215	Y220D	220	Missense	distal	5	no	24.434	24.512	PhosphoSitePlus	TCGA;ICGC;COSMIC;GDSC;CCLE	14.946	Up-regulation
STE_STE20_PAKB_PAK4_ST	P04637	TP53	O96013	PAK4	S215	V216E	216	Missense	proximal	1	no	24.434	24.031	PhosphoSitePlus	TCGA;ICGC;COSMIC	14.946	Down-regulation
STE_STE20_PAKB_PAK4_ST	P04637	TP53	O96013	PAK4	S215	R209K	209	Missense	distal	-6	no	24.434	24.451	PhosphoSitePlus	TCGA;COSMIC	14.946	Up-regulation
STE_STE20_PAKB_PAK4_ST	P04637	TP53	O96013	PAK4	S215	V218G	218	Missense	distal	3	no	24.434	24.232	PhosphoSitePlus	TCGA;ICGC;COSMIC	14.946	Down-regulation
STE_STE20_PAKB_PAK4_ST	P04637	TP53	O96013	PAK4	S215	R213P	213	Missense	proximal	-2	no	24.434	18.665	PhosphoSitePlus	TCGA;ICGC;COSMIC	14.946	Down-regulation
STE_STE20_PAKB_PAK4_ST	P04637	TP53	O96013	PAK4	S215	H214L	214	Missense	proximal	-1	no	24.434	23.519	PhosphoSitePlus	TCGA;ICGC;COSMIC	14.946	Down-regulation
STE_STE20_PAKB_PAK4_ST	P04637	TP53	O96013	PAK4	S215	V216L	216	Missense	proximal	1	no	24.434	25.744	PhosphoSitePlus	TCGA;ICGC;COSMIC;GDSC;CCLE	14.946	Up-regulation
STE_STE20_PAKB_PAK4_ST	P04637	TP53	O96013	PAK4	S215	D208G	208	Missense	distal	-7	no	24.434	24.035	PhosphoSitePlus	TCGA;ICGC;COSMIC	14.946	Down-regulation
STE_STE20_PAKB_PAK4_ST	P04637	TP53	O96013	PAK4	S215	S215G	215	Missense	central	0	yes	24.434	0.000	PhosphoSitePlus	TCGA;ICGC;COSMIC;GDSC;CCLE	14.946	Loss
STE_STE20_PAKB_PAK4_ST	P04637	TP53	O96013	PAK4	S215	R209S	209	Missense	distal	-6	no	24.434	24.324	PhosphoSitePlus	TCGA;ICGC;COSMIC	14.946	Down-regulation
STE_STE20_PAKB_PAK4_ST	P04637	TP53	O96013	PAK4	S215	R213G	213	Missense	proximal	-2	no	24.434	19.747	PhosphoSitePlus	TCGA;ICGC;COSMIC	14.946	Down-regulation
STE_STE20_PAKB_PAK4_ST	P04637	TP53	O96013	PAK4	S215	S215R	215	Missense	central	0	yes	24.434	0.000	PhosphoSitePlus	TCGA;ICGC;COSMIC;GDSC;CCLE	14.946	Loss
STE_STE20_PAKB_PAK4_ST	P04637	TP53	O96013	PAK4	S215	R209I	209	Missense	distal	-6	no	24.434	24.183	PhosphoSitePlus	TCGA;ICGC;COSMIC	14.946	Down-regulation
STE_STE20_PAKB_PAK4_ST	P04637	TP53	O96013	PAK4	S215	T211A	211	Missense	distal	-4	no	24.434	25.485	PhosphoSitePlus	TCGA;ICGC;COSMIC;CCLE	14.946	Up-regulation
STE_STE20_PAKB_PAK4_ST	P04637	TP53	O96013	PAK4	S269	G266R	266	Missense	distal	-3	no	10.413	16.661	EPSD	TCGA;ICGC;COSMIC;GDSC;CCLE	14.946	Gain
STE_STE20_PAKB_PAK4_ST	P04637	TP53	O96013	PAK4	S371	S376C	376	Missense	distal	5	no	21.189	20.985	EPSD	TCGA;ICGC;COSMIC	14.946	Down-regulation
STE_STE20_PAKB_PAK4_ST	P04637	TP53	O96013	PAK4	S371	Q375K	375	Missense	distal	4	no	21.189	21.183	EPSD	TCGA;ICGC;COSMIC	14.946	Down-regulation
STE_STE20_PAKB_PAK4_ST	P04637	TP53	O96013	PAK4	S376	S376C	376	Missense	central	0	yes	18.237	0.000	EPSD	TCGA;ICGC;COSMIC	14.946	Loss
STE_STE20_PAKB_PAK4_ST	P04637	TP53	O96013	PAK4	S376	Q375K	375	Missense	proximal	-1	no	18.237	20.627	EPSD	TCGA;ICGC;COSMIC	14.946	Up-regulation
STE_STE20_PAKB_PAK4_ST	P04637	TP53	O96013	PAK4	S378	S376C	376	Missense	proximal	-2	no	15.211	12.669	EPSD	TCGA;ICGC;COSMIC	14.946	Loss
STE_STE20_PAKB_PAK4_ST	P04637	TP53	O96013	PAK4	S378	Q375K	375	Missense	distal	-3	no	15.211	20.719	EPSD	TCGA;ICGC;COSMIC	14.946	Up-regulation
STE_STE20_PAKB_PAK4_ST	P53667	LIMK1	O96013	PAK4	S58	C52Y	52	Missense	distal	-6	no	15.603	15.800	EPSD	TCGA;COSMIC	14.946	Up-regulation
STE_STE20_PAKB_PAK4_ST	P53667	LIMK1	O96013	PAK4	S58	S60L	60	Missense	proximal	2	no	15.603	13.209	EPSD	TCGA;COSMIC	14.946	Loss
STE_STE20_PAKB_PAK4_ST	P53667	LIMK1	O96013	PAK4	S296	R289Q	289	Missense	distal	-7	no	17.236	14.892	EPSD	TCGA;COSMIC	14.946	Loss
STE_STE20_PAKB_PAK4_ST	P53667	LIMK1	O96013	PAK4	S296	P303T	303	Missense	distal	7	no	17.236	17.014	EPSD	TCGA;COSMIC	14.946	Down-regulation
STE_STE20_PAKB_PAK4_ST	P53667	LIMK1	O96013	PAK4	S296	R289W	289	Missense	distal	-7	no	17.236	13.990	EPSD	TCGA;COSMIC	14.946	Loss
STE_STE20_PAKB_PAK4_ST	P53667	LIMK1	O96013	PAK4	S302	P303T	303	Missense	proximal	1	no	16.285	18.197	EPSD	TCGA;COSMIC	14.946	Up-regulation
STE_STE20_PAKB_PAK4_ST	P53667	LIMK1	O96013	PAK4	S302	L308P	308	Missense	distal	6	no	16.285	16.108	EPSD	TCGA;COSMIC	14.946	Down-regulation
STE_STE20_PAKB_PAK4_ST	P53667	LIMK1	O96013	PAK4	S321	R325H	325	Missense	distal	4	no	16.722	16.756	EPSD	TCGA	14.946	Up-regulation
STE_STE20_PAKB_PAK4_ST	P53667	LIMK1	O96013	PAK4	S321	R315H	315	Missense	distal	-6	no	16.722	16.553	EPSD	TCGA;COSMIC	14.946	Down-regulation
STE_STE20_PAKB_PAK4_ST	P53667	LIMK1	O96013	PAK4	S321	S321C	321	Missense	central	0	yes	16.722	0.000	EPSD	TCGA;COSMIC	14.946	Loss
STE_STE20_PAKB_PAK4_ST	P53667	LIMK1	O96013	PAK4	S321	R320C	320	Missense	proximal	-1	no	16.722	11.998	EPSD	TCGA;COSMIC	14.946	Loss
STE_STE20_PAKB_PAK4_ST	P53667	LIMK1	O96013	PAK4	S323	R329Q	329	Missense	distal	6	no	21.679	22.072	EPSD	TCGA;COSMIC	14.946	Up-regulation
STE_STE20_PAKB_PAK4_ST	P53667	LIMK1	O96013	PAK4	S323	R329W	329	Missense	distal	6	no	21.679	22.235	EPSD	TCGA;COSMIC	14.946	Up-regulation
STE_STE20_PAKB_PAK4_ST	P53667	LIMK1	O96013	PAK4	S323	R325H	325	Missense	proximal	2	no	21.679	21.932	EPSD	TCGA	14.946	Up-regulation
STE_STE20_PAKB_PAK4_ST	P53667	LIMK1	O96013	PAK4	S323	S321C	321	Missense	proximal	-2	no	21.679	19.137	EPSD	TCGA;COSMIC	14.946	Down-regulation
STE_STE20_PAKB_PAK4_ST	P53667	LIMK1	O96013	PAK4	S323	R320C	320	Missense	distal	-3	no	21.679	14.157	EPSD	TCGA;COSMIC	14.946	Loss
STE_STE20_PAKB_PAK4_ST	P53667	LIMK1	O96013	PAK4	T508	D502G	502	Missense	distal	-6	no	26.601	26.543	PhosphoSitePlus	TCGA;COSMIC	14.946	Down-regulation
STE_STE20_PAKB_PAK4_ST	P53667	LIMK1	O96013	PAK4	T508	P513L	513	Missense	distal	5	no	26.601	26.341	PhosphoSitePlus	TCGA;COSMIC	14.946	Down-regulation
STE_STE20_PAKB_PAK4_ST	P03372	ESR1	O96013	PAK4	S10	Q17H	17	Missense	distal	7	no	15.151	15.205	EPSD	TCGA;ICGC;COSMIC	14.946	Up-regulation
STE_STE20_PAKB_PAK4_ST	P03372	ESR1	O96013	PAK4	S10	A9T	9	Missense	proximal	-1	no	15.151	12.734	EPSD	TCGA;COSMIC	14.946	Loss
STE_STE20_PAKB_PAK4_ST	P03372	ESR1	O96013	PAK4	S10	S10C	10	Missense	central	0	yes	15.151	0.000	EPSD	TCGA;ICGC;COSMIC	14.946	Loss
STE_STE20_PAKB_PAK4_ST	P03372	ESR1	O96013	PAK4	S10	A13T	13	Missense	distal	3	no	15.151	14.518	EPSD	TCGA;ICGC;COSMIC	14.946	Loss
STE_STE20_PAKB_PAK4_ST	P03372	ESR1	O96013	PAK4	S167	A166S	166	Missense	proximal	-1	no	19.706	19.212	EPSD	TCGA;ICGC;COSMIC	14.946	Down-regulation
STE_STE20_PAKB_PAK4_ST	P03372	ESR1	O96013	PAK4	S167	K171M	171	Missense	distal	4	no	19.706	19.680	EPSD	TCGA;ICGC;COSMIC	14.946	Down-regulation
STE_STE20_PAKB_PAK4_ST	P03372	ESR1	O96013	PAK4	S212	K206R	206	Missense	distal	-6	no	16.546	16.530	EPSD	TCGA;ICGC;COSMIC	14.946	Down-regulation
STE_STE20_PAKB_PAK4_ST	P03372	ESR1	O96013	PAK4	S212	N217S	217	Missense	distal	5	no	16.546	16.626	EPSD	TCGA;ICGC;COSMIC	14.946	Up-regulation
STE_STE20_PAKB_PAK4_ST	P03372	ESR1	O96013	PAK4	S212	D218N	218	Missense	distal	6	no	16.546	16.583	EPSD	TCGA;ICGC;COSMIC	14.946	Up-regulation
STE_STE20_PAKB_PAK4_ST	P03372	ESR1	O96013	PAK4	S212	A207T	207	Missense	distal	-5	no	16.546	16.212	EPSD	TCGA;ICGC;COSMIC	14.946	Down-regulation
STE_STE20_PAKB_PAK4_ST	P03372	ESR1	O96013	PAK4	S236	K235N	235	Missense	proximal	-1	no	17.263	14.840	EPSD	TCGA;ICGC;COSMIC	14.946	Loss
STE_STE20_PAKB_PAK4_ST	P03372	ESR1	O96013	PAK4	S236	A239S	239	Missense	distal	3	no	17.263	16.405	EPSD	TCGA;ICGC;COSMIC	14.946	Down-regulation
STE_STE20_PAKB_PAK4_ST	P03372	ESR1	O96013	PAK4	S236	R243H	243	Missense	distal	7	no	17.263	17.353	EPSD	TCGA;ICGC;COSMIC	14.946	Up-regulation
STE_STE20_PAKB_PAK4_ST	P03372	ESR1	O96013	PAK4	S236	R243C	243	Missense	distal	7	no	17.263	17.547	EPSD	TCGA;ICGC;COSMIC	14.946	Up-regulation
STE_STE20_PAKB_PAK4_ST	P03372	ESR1	O96013	PAK4	S236	C240Y	240	Missense	distal	4	no	17.263	17.032	EPSD	TCGA;ICGC;COSMIC	14.946	Down-regulation
STE_STE20_PAKB_PAK4_ST	P03372	ESR1	O96013	PAK4	S305	I298M	298	Missense	distal	-7	no	28.139	29.583	PhosphoSitePlus	TCGA;ICGC;COSMIC	14.946	Up-regulation
STE_STE20_PAKB_PAK4_ST	P03372	ESR1	O96013	PAK4	S305	A307S	307	Missense	proximal	2	no	28.139	28.456	PhosphoSitePlus	TCGA;ICGC;COSMIC	14.946	Up-regulation
STE_STE20_PAKB_PAK4_ST	P03372	ESR1	O96013	PAK4	S305	T311M	311	Missense	distal	6	no	28.139	28.076	PhosphoSitePlus	TCGA;ICGC;COSMIC	14.946	Down-regulation
STE_STE20_PAKB_PAK4_ST	P03372	ESR1	O96013	PAK4	S576	S575L	575	Missense	proximal	-1	no	16.807	15.659	EPSD	TCGA;ICGC;COSMIC	14.946	Down-regulation
STE_STE20_PAKB_PAK4_ST	P03372	ESR1	O96013	PAK4	S576	K581T	581	Missense	distal	5	no	16.807	16.729	EPSD	TCGA;ICGC	14.946	Down-regulation
STE_STE20_PAKB_PAK4_ST	Q93045	STMN2	O96013	PAK4	S16	M12V	12	Missense	distal	-4	no	15.340	15.044	EPSD	TCGA;ICGC;COSMIC	14.946	Down-regulation
STE_STE20_PAKB_PAK4_ST	Q93045	STMN2	O96013	PAK4	S50	E55Q	55	Missense	distal	5	no	25.990	25.968	PhosphoSitePlus	TCGA	14.946	Down-regulation
STE_STE20_PAKB_PAK4_ST	Q93045	STMN2	O96013	PAK4	S50	A49S	49	Missense	proximal	-1	no	25.990	25.495	PhosphoSitePlus	TCGA;ICGC;COSMIC	14.946	Down-regulation
STE_STE20_PAKB_PAK4_ST	Q93045	STMN2	O96013	PAK4	S80	S80F	80	Missense	central	0	yes	15.305	0.000	EPSD	TCGA;ICGC;COSMIC	14.946	Loss
STE_STE20_PAKB_PAK4_ST	Q93045	STMN2	O96013	PAK4	S97	K104N	104	Missense	distal	7	no	24.764	24.973	EPSD	TCGA;ICGC;COSMIC	14.946	Up-regulation
CAMK_MLCK_MYLK2_ST	Q06413	MEF2C	Q9H1R3	MYLK2	T70	H76L	76	Missense	distal	6	no	3.520	3.637	EPSD	TCGA	3.166	Up-regulation
CAMK_MLCK_MYLK2_ST	Q06413	MEF2C	Q9H1R3	MYLK2	T70	E74V	74	Missense	distal	4	no	3.520	3.532	EPSD	TCGA;ICGC;COSMIC	3.166	Up-regulation
CAMK_MLCK_MYLK2_ST	Q06413	MEF2C	Q9H1R3	MYLK2	T70	D63G	63	Missense	distal	-7	no	3.520	3.523	EPSD	TCGA;ICGC;COSMIC	3.166	Up-regulation
CAMK_MLCK_MYLK2_ST	Q06413	MEF2C	Q9H1R3	MYLK2	T70	Y72C	72	Missense	proximal	2	no	3.520	3.504	EPSD	TCGA;ICGC;COSMIC	3.166	Down-regulation
CAMK_MLCK_MYLK2_ST	Q06413	MEF2C	Q9H1R3	MYLK2	T70	T70P	70	Missense	central	0	yes	3.520	0.000	EPSD	TCGA;ICGC;COSMIC	3.166	Loss
CAMK_MLCK_MYLK2_ST	Q06413	MEF2C	Q9H1R3	MYLK2	T80	H76L	76	Missense	distal	-4	no	7.263	7.202	PhosphoSitePlus	TCGA	3.166	Down-regulation
CAMK_MLCK_MYLK2_ST	Q06413	MEF2C	Q9H1R3	MYLK2	T80	E74V	74	Missense	distal	-6	no	7.263	6.944	PhosphoSitePlus	TCGA;ICGC;COSMIC	3.166	Down-regulation
CAMK_MLCK_MYLK2_ST	Q06413	MEF2C	Q9H1R3	MYLK2	T80	V85M	85	Missense	distal	5	no	7.263	7.245	PhosphoSitePlus	TCGA;ICGC;COSMIC	3.166	Down-regulation
CAMK_RAD53_CHEK2_ST	P04637	TP53	O96017	CHEK2	T81	A79V	79	Missense	proximal	-2	no	9.581	9.139	EPSD	TCGA;ICGC;COSMIC	8.561	Down-regulation
CAMK_RAD53_CHEK2_ST	P04637	TP53	O96017	CHEK2	T81	P77L	77	Missense	distal	-4	no	9.581	8.804	EPSD	TCGA;ICGC;COSMIC	8.561	Down-regulation
CAMK_RAD53_CHEK2_ST	P04637	TP53	O96017	CHEK2	T81	P82L	82	Missense	proximal	1	no	9.581	10.871	EPSD	TCGA;ICGC;COSMIC	8.561	Up-regulation
CAMK_RAD53_CHEK2_ST	P04637	TP53	O96017	CHEK2	T81	A74T	74	Missense	distal	-7	no	9.581	9.798	EPSD	TCGA;ICGC;COSMIC	8.561	Up-regulation
CAMK_RAD53_CHEK2_ST	P04637	TP53	O96017	CHEK2	S99	G105C	105	Missense	distal	6	no	8.743	8.830	EPSD	TCGA;ICGC;COSMIC;GDSC	8.561	Up-regulation
CAMK_RAD53_CHEK2_ST	P04637	TP53	O96017	CHEK2	S99	S106R	106	Missense	distal	7	no	8.743	8.745	EPSD	TCGA;ICGC;COSMIC;GDSC;CCLE	8.561	Up-regulation
CAMK_RAD53_CHEK2_ST	P04637	TP53	O96017	CHEK2	S99	G105R	105	Missense	distal	6	no	8.743	9.035	EPSD	TCGA;ICGC;COSMIC;CCLE	8.561	Up-regulation
CAMK_RAD53_CHEK2_ST	P04637	TP53	O96017	CHEK2	S99	G105V	105	Missense	distal	6	no	8.743	8.651	EPSD	TCGA;ICGC;COSMIC	8.561	Down-regulation
CAMK_RAD53_CHEK2_ST	P04637	TP53	O96017	CHEK2	S99	G105D	105	Missense	distal	6	no	8.743	8.557	EPSD	TCGA;ICGC;COSMIC	8.561	Loss
CAMK_RAD53_CHEK2_ST	P04637	TP53	O96017	CHEK2	S99	G105S	105	Missense	distal	6	no	8.743	8.970	EPSD	TCGA;ICGC;COSMIC	8.561	Up-regulation
CAMK_RAD53_CHEK2_ST	P04637	TP53	O96017	CHEK2	S99	V97D	97	Missense	proximal	-2	no	8.743	8.325	EPSD	TCGA;ICGC;COSMIC	8.561	Loss
CAMK_RAD53_CHEK2_ST	P04637	TP53	O96017	CHEK2	S99	P92S	92	Missense	distal	-7	no	8.743	8.979	EPSD	TCGA;ICGC	8.561	Up-regulation
CAMK_RAD53_CHEK2_ST	P04637	TP53	O96017	CHEK2	S183	E180K	180	Missense	distal	-3	no	6.465	9.292	EPSD	TCGA;ICGC;COSMIC;CCLE	8.561	Gain
CAMK_RAD53_CHEK2_ST	P04637	TP53	O96017	CHEK2	S269	R273C	273	Missense	distal	4	no	12.111	12.516	EPSD	TCGA;ICGC;COSMIC;GDSC;CCLE	8.561	Up-regulation
CAMK_RAD53_CHEK2_ST	P04637	TP53	O96017	CHEK2	S269	C275S	275	Missense	distal	6	no	12.111	12.251	EPSD	TCGA;ICGC;COSMIC	8.561	Up-regulation
CAMK_RAD53_CHEK2_ST	P04637	TP53	O96017	CHEK2	S269	R273L	273	Missense	distal	4	no	12.111	12.384	EPSD	TCGA;ICGC;COSMIC;GDSC;CCLE	8.561	Up-regulation
CAMK_RAD53_CHEK2_ST	P04637	TP53	O96017	CHEK2	S269	E271K	271	Missense	proximal	2	no	12.111	12.196	EPSD	TCGA;ICGC;COSMIC;GDSC;CCLE	8.561	Up-regulation
CAMK_RAD53_CHEK2_ST	P04637	TP53	O96017	CHEK2	S269	C275Y	275	Missense	distal	6	no	12.111	11.657	EPSD	TCGA;ICGC;COSMIC;GDSC;CCLE	8.561	Down-regulation
CAMK_RAD53_CHEK2_ST	P04637	TP53	O96017	CHEK2	S269	R273S	273	Missense	distal	4	no	12.111	12.064	EPSD	TCGA;ICGC;COSMIC	8.561	Down-regulation
CAMK_RAD53_CHEK2_ST	P04637	TP53	O96017	CHEK2	S269	E271Q	271	Missense	proximal	2	no	12.111	12.047	EPSD	TCGA;ICGC;COSMIC	8.561	Down-regulation
CAMK_RAD53_CHEK2_ST	P04637	TP53	O96017	CHEK2	S269	L265P	265	Missense	distal	-4	no	12.111	12.887	EPSD	TCGA;ICGC;COSMIC;GDSC;CCLE	8.561	Up-regulation
CAMK_RAD53_CHEK2_ST	P04637	TP53	O96017	CHEK2	S269	V272M	272	Missense	distal	3	no	12.111	11.899	EPSD	TCGA;ICGC;COSMIC;GDSC;CCLE	8.561	Down-regulation
CAMK_RAD53_CHEK2_ST	P04637	TP53	O96017	CHEK2	S269	G266E	266	Missense	distal	-3	no	12.111	10.105	EPSD	TCGA;ICGC;COSMIC;GDSC;CCLE	8.561	Down-regulation
CAMK_RAD53_CHEK2_ST	P04637	TP53	O96017	CHEK2	S269	R273P	273	Missense	distal	4	no	12.111	12.292	EPSD	TCGA;ICGC;COSMIC	8.561	Up-regulation
CAMK_RAD53_CHEK2_ST	P04637	TP53	O96017	CHEK2	S269	F270I	270	Missense	proximal	1	no	12.111	7.979	EPSD	TCGA;ICGC;COSMIC	8.561	Loss
CAMK_RAD53_CHEK2_ST	P04637	TP53	O96017	CHEK2	S269	R273H	273	Missense	distal	4	no	12.111	12.337	EPSD	TCGA;ICGC;COSMIC;GDSC;CCLE	8.561	Up-regulation
CAMK_RAD53_CHEK2_ST	P04637	TP53	O96017	CHEK2	S269	A276P	276	Missense	distal	7	no	12.111	12.108	EPSD	TCGA;ICGC;COSMIC	8.561	Down-regulation
CAMK_RAD53_CHEK2_ST	P04637	TP53	O96017	CHEK2	S269	V272L	272	Missense	distal	3	no	12.111	11.625	EPSD	TCGA;ICGC;COSMIC;GDSC;CCLE	8.561	Down-regulation
CAMK_RAD53_CHEK2_ST	P04637	TP53	O96017	CHEK2	S269	V274D	274	Missense	distal	5	no	12.111	12.025	EPSD	TCGA;ICGC;COSMIC;CCLE	8.561	Down-regulation
CAMK_RAD53_CHEK2_ST	P04637	TP53	O96017	CHEK2	S269	G266V	266	Missense	distal	-3	no	12.111	8.572	EPSD	TCGA;ICGC;COSMIC;GDSC;CCLE	8.561	Down-regulation
CAMK_RAD53_CHEK2_ST	P04637	TP53	O96017	CHEK2	S269	R267L	267	Missense	proximal	-2	no	12.111	11.556	EPSD	TCGA;ICGC;COSMIC;GDSC;CCLE	8.561	Down-regulation
CAMK_RAD53_CHEK2_ST	P04637	TP53	O96017	CHEK2	S269	R267W	267	Missense	proximal	-2	no	12.111	10.470	EPSD	TCGA;ICGC;COSMIC;GDSC;CCLE	8.561	Down-regulation
CAMK_RAD53_CHEK2_ST	P04637	TP53	O96017	CHEK2	S269	R267Q	267	Missense	proximal	-2	no	12.111	11.798	EPSD	TCGA;ICGC;COSMIC;CCLE	8.561	Down-regulation
CAMK_RAD53_CHEK2_ST	P04637	TP53	O96017	CHEK2	S269	C275F	275	Missense	distal	6	no	12.111	11.544	EPSD	TCGA;ICGC;COSMIC;GDSC;CCLE	8.561	Down-regulation
CAMK_RAD53_CHEK2_ST	P04637	TP53	O96017	CHEK2	S269	V274G	274	Missense	distal	5	no	12.111	12.080	EPSD	TCGA;ICGC;COSMIC;CCLE	8.561	Down-regulation
CAMK_RAD53_CHEK2_ST	P04637	TP53	O96017	CHEK2	S269	V274L	274	Missense	distal	5	no	12.111	12.065	EPSD	TCGA;ICGC;COSMIC	8.561	Down-regulation
CAMK_RAD53_CHEK2_ST	P04637	TP53	O96017	CHEK2	S269	G266R	266	Missense	distal	-3	no	12.111	18.017	EPSD	TCGA;ICGC;COSMIC;GDSC;CCLE	8.561	Up-regulation
CAMK_RAD53_CHEK2_ST	P04637	TP53	O96017	CHEK2	S269	R267P	267	Missense	proximal	-2	no	12.111	11.605	EPSD	TCGA;ICGC;COSMIC;GDSC;CCLE	8.561	Down-regulation
CAMK_RAD53_CHEK2_ST	P04637	TP53	O96017	CHEK2	S269	A276D	276	Missense	distal	7	no	12.111	12.129	EPSD	TCGA;ICGC;COSMIC	8.561	Up-regulation
CAMK_RAD53_CHEK2_ST	P04637	TP53	O96017	CHEK2	S269	L265R	265	Missense	distal	-4	no	12.111	13.473	EPSD	TCGA;ICGC;COSMIC	8.561	Up-regulation
CAMK_RAD53_CHEK2_ST	P04637	TP53	O96017	CHEK2	S269	R267G	267	Missense	proximal	-2	no	12.111	11.423	EPSD	TCGA;ICGC;COSMIC	8.561	Down-regulation
CAMK_RAD53_CHEK2_ST	P04637	TP53	O96017	CHEK2	S269	F270C	270	Missense	proximal	1	no	12.111	9.108	EPSD	TCGA;ICGC;COSMIC	8.561	Down-regulation
CAMK_RAD53_CHEK2_ST	P04637	TP53	O96017	CHEK2	S269	E271V	271	Missense	proximal	2	no	12.111	12.031	EPSD	TCGA;ICGC;COSMIC	8.561	Down-regulation
CAMK_RAD53_CHEK2_ST	P04637	TP53	O96017	CHEK2	S269	G262V	262	Missense	distal	-7	no	12.111	10.922	EPSD	TCGA;ICGC;COSMIC;GDSC;CCLE	8.561	Down-regulation
CAMK_RAD53_CHEK2_ST	P04637	TP53	O96017	CHEK2	S269	V274F	274	Missense	distal	5	no	12.111	11.874	EPSD	TCGA;ICGC;COSMIC;GDSC;CCLE	8.561	Down-regulation
CAMK_RAD53_CHEK2_ST	P04637	TP53	O96017	CHEK2	S269	F270S	270	Missense	proximal	1	no	12.111	7.355	EPSD	TCGA;ICGC;COSMIC	8.561	Loss
CAMK_RAD53_CHEK2_ST	P04637	TP53	O96017	CHEK2	S269	C275R	275	Missense	distal	6	no	12.111	12.316	EPSD	TCGA;ICGC;COSMIC	8.561	Up-regulation
CAMK_RAD53_CHEK2_ST	P04637	TP53	O96017	CHEK2	S269	C275G	275	Missense	distal	6	no	12.111	12.023	EPSD	TCGA;ICGC;COSMIC;GDSC;CCLE	8.561	Down-regulation
CAMK_RAD53_CHEK2_ST	P04637	TP53	O96017	CHEK2	S269	V272G	272	Missense	distal	3	no	12.111	12.156	EPSD	TCGA;ICGC;COSMIC	8.561	Up-regulation
CAMK_RAD53_CHEK2_ST	P04637	TP53	O96017	CHEK2	S269	R273G	273	Missense	distal	4	no	12.111	12.754	EPSD	TCGA;ICGC;COSMIC	8.561	Up-regulation
CAMK_RAD53_CHEK2_ST	P04637	TP53	O96017	CHEK2	S269	F270V	270	Missense	proximal	1	no	12.111	8.564	EPSD	TCGA;ICGC;COSMIC	8.561	Down-regulation
CAMK_RAD53_CHEK2_ST	P04637	TP53	O96017	CHEK2	S269	C275W	275	Missense	distal	6	no	12.111	11.439	EPSD	TCGA;ICGC;COSMIC	8.561	Down-regulation
CAMK_RAD53_CHEK2_ST	P04637	TP53	O96017	CHEK2	S269	V272A	272	Missense	distal	3	no	12.111	11.446	EPSD	TCGA;ICGC;COSMIC	8.561	Down-regulation
CAMK_RAD53_CHEK2_ST	P04637	TP53	O96017	CHEK2	S269	F270L	270	Missense	proximal	1	no	12.111	10.163	EPSD	TCGA;ICGC;COSMIC	8.561	Down-regulation
CAMK_RAD53_CHEK2_ST	P04637	TP53	O96017	CHEK2	S371	S376C	376	Missense	distal	5	no	9.892	9.776	EPSD	TCGA;ICGC;COSMIC	8.561	Down-regulation
CAMK_RAD53_CHEK2_ST	P04637	TP53	O96017	CHEK2	S371	Q375K	375	Missense	distal	4	no	9.892	10.241	EPSD	TCGA;ICGC;COSMIC	8.561	Up-regulation
CAMK_RAD53_CHEK2_ST	P04637	TP53	O96017	CHEK2	S378	Q375K	375	Missense	distal	-3	no	4.197	9.061	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	8.561	Gain
CAMK_RAD53_CHEK2_ST	O00716	E2F3	O96017	CHEK2	S163	G157E	157	Missense	distal	-6	no	10.585	10.612	EPSD	TCGA;ICGC	8.561	Up-regulation
CAMK_RAD53_CHEK2_ST	O00716	E2F3	O96017	CHEK2	S163	R158K	158	Missense	distal	-5	no	10.585	9.999	EPSD	TCGA;ICGC;COSMIC	8.561	Down-regulation
CAMK_RAD53_CHEK2_ST	O00716	E2F3	O96017	CHEK2	S163	R162Q	162	Missense	proximal	-1	no	10.585	10.605	EPSD	TCGA;ICGC;COSMIC	8.561	Up-regulation
CAMK_RAD53_CHEK2_ST	O00716	E2F3	O96017	CHEK2	T181	T181M	181	Missense	central	0	yes	10.130	0.000	EPSD	TCGA;ICGC;COSMIC	8.561	Loss
CAMK_RAD53_CHEK2_ST	O00716	E2F3	O96017	CHEK2	T181	L186R	186	Missense	distal	5	no	10.130	10.387	EPSD	TCGA;ICGC;COSMIC;GDSC;CCLE	8.561	Up-regulation
CAMK_RAD53_CHEK2_ST	O00716	E2F3	O96017	CHEK2	T181	R178W	178	Missense	distal	-3	no	10.130	-3.099	EPSD	TCGA;ICGC	8.561	Loss
CAMK_RAD53_CHEK2_ST	O00716	E2F3	O96017	CHEK2	S308	R305Q	305	Missense	distal	-3	no	10.470	0.521	EPSD	TCGA;ICGC;COSMIC	8.561	Loss
CAMK_RAD53_CHEK2_ST	O43255	SIAH2	O96017	CHEK2	S167	E162Q	162	Missense	distal	-5	no	8.149	9.032	EPSD	TCGA;ICGC;COSMIC	8.561	Gain
CAMK_RAD53_CHEK2_ST	O96017	CHEK2	O96017	CHEK2	S19	S24C	24	Missense	distal	5	no	9.661	9.545	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	8.561	Down-regulation
CAMK_RAD53_CHEK2_ST	O96017	CHEK2	O96017	CHEK2	S19	C18S	18	Missense	proximal	-1	no	9.661	9.473	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	8.561	Down-regulation
CAMK_RAD53_CHEK2_ST	O96017	CHEK2	O96017	CHEK2	S19	S16R	16	Missense	distal	-3	no	9.661	16.518	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	8.561	Up-regulation
CAMK_RAD53_CHEK2_ST	O96017	CHEK2	O96017	CHEK2	T26	S24C	24	Missense	proximal	-2	no	12.425	12.169	EPSD	TCGA;ICGC;COSMIC	8.561	Down-regulation
CAMK_RAD53_CHEK2_ST	O96017	CHEK2	O96017	CHEK2	S35	S42C	42	Missense	distal	7	no	10.340	10.356	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	8.561	Up-regulation
CAMK_RAD53_CHEK2_ST	O96017	CHEK2	O96017	CHEK2	S44	S42C	42	Missense	proximal	-2	no	8.832	8.575	EPSD	TCGA;ICGC;COSMIC	8.561	Down-regulation
CAMK_RAD53_CHEK2_ST	O96017	CHEK2	O96017	CHEK2	S50	S53F	53	Missense	distal	3	no	9.393	10.141	EPSD	TCGA;ICGC;COSMIC	8.561	Up-regulation
CAMK_RAD53_CHEK2_ST	O96017	CHEK2	O96017	CHEK2	S50	S56R	56	Missense	distal	6	no	9.393	9.458	EPSD	TCGA;ICGC;COSMIC	8.561	Up-regulation
CAMK_RAD53_CHEK2_ST	O96017	CHEK2	O96017	CHEK2	T68	E70G	70	Missense	proximal	2	no	9.703	9.764	EPSD;PhosphoSitePlus	TCGA	8.561	Up-regulation
CAMK_RAD53_CHEK2_ST	O96017	CHEK2	O96017	CHEK2	T389	E394D	394	Missense	distal	5	no	9.292	9.184	EPSD	TCGA;COSMIC	8.561	Down-regulation
CAMK_RAD53_CHEK2_ST	P33981	TTK	O96017	CHEK2	S15	T12R	12	Missense	distal	-3	no	3.267	11.810	EPSD	TCGA;ICGC;COSMIC	8.561	Gain
CAMK_RAD53_CHEK2_ST	P33981	TTK	O96017	CHEK2	S108	Q105H	105	Missense	distal	-3	no	3.214	9.430	EPSD	TCGA	8.561	Gain
CAMK_RAD53_CHEK2_ST	P33981	TTK	O96017	CHEK2	S214	G217S	217	Missense	distal	3	no	11.199	10.499	EPSD	TCGA;ICGC;COSMIC	8.561	Down-regulation
CAMK_RAD53_CHEK2_ST	P33981	TTK	O96017	CHEK2	S329	N326H	326	Missense	distal	-3	no	3.695	8.659	EPSD	TCGA;ICGC;COSMIC	8.561	Gain
CAMK_RAD53_CHEK2_ST	P33981	TTK	O96017	CHEK2	S526	S519L	519	Missense	distal	-7	no	10.853	9.907	EPSD	TCGA;COSMIC	8.561	Down-regulation
CAMK_RAD53_CHEK2_ST	P33981	TTK	O96017	CHEK2	S526	I524M	524	Missense	proximal	-2	no	10.853	10.649	EPSD	TCGA;COSMIC	8.561	Down-regulation
CAMK_RAD53_CHEK2_ST	P33981	TTK	O96017	CHEK2	T686	Q683R	683	Missense	distal	-3	no	4.925	14.874	EPSD	TCGA;COSMIC	8.561	Gain
CAMK_RAD53_CHEK2_ST	P33981	TTK	O96017	CHEK2	T831	S824F	824	Missense	distal	-7	no	10.742	7.347	EPSD	TCGA;COSMIC	8.561	Loss
CAMK_RAD53_CHEK2_ST	P33981	TTK	O96017	CHEK2	S845	G839S	839	Missense	distal	-6	no	8.522	8.791	EPSD	TCGA;COSMIC	8.561	Gain
CAMK_RAD53_CHEK2_ST	P33981	TTK	O96017	CHEK2	T849	R854G	854	Missense	distal	5	no	9.416	9.174	EPSD	TCGA;COSMIC;CCLE	8.561	Down-regulation
CAMK_RAD53_CHEK2_ST	P33981	TTK	O96017	CHEK2	T849	R854K	854	Missense	distal	5	no	9.416	9.261	EPSD	TCGA;COSMIC	8.561	Down-regulation
CAMK_RAD53_CHEK2_ST	Q9NY61	AATF	O96017	CHEK2	S93	S94F	94	Missense	proximal	1	no	3.993	8.749	EPSD	TCGA;ICGC	8.561	Gain
CAMK_RAD53_CHEK2_ST	Q9NY61	AATF	O96017	CHEK2	S141	P147S	147	Missense	distal	6	no	9.381	9.303	EPSD	TCGA;ICGC	8.561	Down-regulation
CAMK_RAD53_CHEK2_ST	Q9NY61	AATF	O96017	CHEK2	S143	P147S	147	Missense	distal	4	no	13.197	12.970	EPSD;PhosphoSitePlus	TCGA;ICGC	8.561	Down-regulation
CAMK_RAD53_CHEK2_ST	Q9NY61	AATF	O96017	CHEK2	S143	F149S	149	Missense	distal	6	no	13.197	13.905	EPSD;PhosphoSitePlus	TCGA;ICGC	8.561	Up-regulation
CAMK_RAD53_CHEK2_ST	Q9NY61	AATF	O96017	CHEK2	T366	H371R	371	Missense	distal	5	no	8.634	8.748	EPSD	TCGA;ICGC	8.561	Up-regulation
CAMK_RAD53_CHEK2_ST	Q9NY61	AATF	O96017	CHEK2	T366	R365H	365	Missense	proximal	-1	no	8.634	8.888	EPSD	TCGA;ICGC	8.561	Up-regulation
CAMK_RAD53_CHEK2_ST	Q9NY61	AATF	O96017	CHEK2	T394	D397N	397	Missense	distal	3	no	11.798	11.329	EPSD	TCGA;ICGC	8.561	Down-regulation
CAMK_RAD53_CHEK2_ST	Q9NY61	AATF	O96017	CHEK2	T394	M401I	401	Missense	distal	7	no	11.798	11.807	EPSD	TCGA;ICGC	8.561	Up-regulation
CAMK_RAD53_CHEK2_ST	Q9NY61	AATF	O96017	CHEK2	T412	R405S	405	Missense	distal	-7	no	12.808	13.211	EPSD	TCGA;ICGC	8.561	Up-regulation
CAMK_RAD53_CHEK2_ST	Q9NY61	AATF	O96017	CHEK2	T412	R414H	414	Missense	proximal	2	no	12.808	12.784	EPSD	TCGA;ICGC	8.561	Down-regulation
CAMK_RAD53_CHEK2_ST	Q9NY61	AATF	O96017	CHEK2	T412	R418Q	418	Missense	distal	6	no	12.808	12.581	EPSD	TCGA;ICGC;CCLE	8.561	Down-regulation
CAMK_RAD53_CHEK2_ST	Q9NY61	AATF	O96017	CHEK2	T412	R408Q	408	Missense	distal	-4	no	12.808	12.906	EPSD	TCGA;ICGC	8.561	Up-regulation
CAMK_RAD53_CHEK2_ST	Q9NY61	AATF	O96017	CHEK2	S477	S478F	478	Missense	proximal	1	no	10.499	15.255	EPSD;PhosphoSitePlus	TCGA;ICGC	8.561	Up-regulation
CAMK_RAD53_CHEK2_ST	Q9NY61	AATF	O96017	CHEK2	S477	I472M	472	Missense	distal	-5	no	10.499	10.311	EPSD;PhosphoSitePlus	TCGA;ICGC	8.561	Down-regulation
CAMK_RAD53_CHEK2_ST	Q9NY61	AATF	O96017	CHEK2	S477	R474W	474	Missense	distal	-3	no	10.499	-2.729	EPSD;PhosphoSitePlus	TCGA;ICGC	8.561	Loss
CAMK_RAD53_CHEK2_ST	Q9NY61	AATF	O96017	CHEK2	S510	R516W	516	Missense	distal	6	no	11.310	10.433	PhosphoSitePlus;EPSD	TCGA;ICGC	8.561	Down-regulation
CAMK_RAD53_CHEK2_ST	Q08050	FOXM1	O96017	CHEK2	S192	R198H	198	Missense	distal	6	no	8.816	8.902	EPSD	TCGA;ICGC;COSMIC	8.561	Up-regulation
CAMK_RAD53_CHEK2_ST	Q08050	FOXM1	O96017	CHEK2	T319	L318F	318	Missense	proximal	-1	no	10.462	11.064	EPSD	TCGA;ICGC;COSMIC	8.561	Up-regulation
CAMK_RAD53_CHEK2_ST	Q08050	FOXM1	O96017	CHEK2	T319	Q322L	322	Missense	distal	3	no	10.462	11.121	EPSD	TCGA;ICGC;COSMIC	8.561	Up-regulation
CAMK_RAD53_CHEK2_ST	Q08050	FOXM1	O96017	CHEK2	T319	D321G	321	Missense	proximal	2	no	10.462	10.714	EPSD	TCGA;ICGC;COSMIC	8.561	Up-regulation
CAMK_RAD53_CHEK2_ST	Q08050	FOXM1	O96017	CHEK2	S340	S340L	340	Missense	central	0	yes	9.446	0.000	EPSD	TCGA;ICGC;COSMIC	8.561	Loss
CAMK_RAD53_CHEK2_ST	Q08050	FOXM1	O96017	CHEK2	T354	E348D	348	Missense	distal	-6	no	15.248	14.931	EPSD	TCGA;ICGC;COSMIC	8.561	Down-regulation
CAMK_RAD53_CHEK2_ST	Q08050	FOXM1	O96017	CHEK2	T354	T357A	357	Missense	distal	3	no	15.248	15.073	EPSD	TCGA;ICGC	8.561	Down-regulation
CAMK_RAD53_CHEK2_ST	Q08050	FOXM1	O96017	CHEK2	T354	R351W	351	Missense	distal	-3	no	15.248	2.020	EPSD	TCGA;ICGC;COSMIC	8.561	Loss
CAMK_RAD53_CHEK2_ST	Q08050	FOXM1	O96017	CHEK2	S376	R373Q	373	Missense	distal	-3	no	12.514	2.565	EPSD	TCGA;ICGC;COSMIC	8.561	Loss
CAMK_RAD53_CHEK2_ST	P18887	XRCC1	O96017	CHEK2	S151	H150Y	150	Missense	proximal	-1	no	13.054	13.654	EPSD	TCGA;ICGC;COSMIC	8.561	Up-regulation
CAMK_RAD53_CHEK2_ST	P18887	XRCC1	O96017	CHEK2	S241	P242L	242	Missense	proximal	1	no	9.554	10.844	EPSD	TCGA;ICGC;COSMIC	8.561	Up-regulation
CAMK_RAD53_CHEK2_ST	P18887	XRCC1	O96017	CHEK2	S266	R272K	272	Missense	distal	6	no	9.337	9.118	EPSD	TCGA;ICGC;COSMIC	8.561	Down-regulation
CAMK_RAD53_CHEK2_ST	P18887	XRCC1	O96017	CHEK2	S266	P270S	270	Missense	distal	4	no	9.337	9.110	EPSD	TCGA;ICGC;COSMIC	8.561	Down-regulation
CAMK_RAD53_CHEK2_ST	P18887	XRCC1	O96017	CHEK2	S266	S266L	266	Missense	central	0	yes	9.337	0.000	EPSD	TCGA;ICGC;COSMIC	8.561	Loss
CAMK_RAD53_CHEK2_ST	P18887	XRCC1	O96017	CHEK2	S266	A263T	263	Missense	distal	-3	no	9.337	6.508	EPSD	TCGA;ICGC;COSMIC;GDSC;CCLE	8.561	Loss
CAMK_RAD53_CHEK2_ST	P18887	XRCC1	O96017	CHEK2	T358	S357N	357	Missense	proximal	-1	no	11.769	12.256	EPSD	TCGA;ICGC	8.561	Up-regulation
CAMK_RAD53_CHEK2_ST	P30304	CDC25A	O96017	CHEK2	S76	S69T	69	Missense	distal	-7	no	12.430	11.583	EPSD	TCGA;ICGC;COSMIC	8.561	Down-regulation
CAMK_RAD53_CHEK2_ST	P30304	CDC25A	O96017	CHEK2	S76	R73K	73	Missense	distal	-3	no	12.430	7.346	EPSD	TCGA;ICGC;COSMIC	8.561	Loss
CAMK_RAD53_CHEK2_ST	P30304	CDC25A	O96017	CHEK2	S76	N70S	70	Missense	distal	-6	no	12.430	12.799	EPSD	TCGA;ICGC;COSMIC	8.561	Up-regulation
CAMK_RAD53_CHEK2_ST	P30304	CDC25A	O96017	CHEK2	S76	E78K	78	Missense	proximal	2	no	12.430	12.516	EPSD	TCGA;ICGC;COSMIC	8.561	Up-regulation
CAMK_RAD53_CHEK2_ST	P30304	CDC25A	O96017	CHEK2	T80	D87Y	87	Missense	distal	7	no	8.924	8.932	EPSD	TCGA;ICGC;COSMIC	8.561	Up-regulation
CAMK_RAD53_CHEK2_ST	P30304	CDC25A	O96017	CHEK2	T80	R73K	73	Missense	distal	-7	no	8.924	8.656	EPSD	TCGA;ICGC;COSMIC	8.561	Down-regulation
CAMK_RAD53_CHEK2_ST	P30304	CDC25A	O96017	CHEK2	T80	E78K	78	Missense	proximal	-2	no	8.924	9.322	EPSD	TCGA;ICGC;COSMIC	8.561	Up-regulation
CAMK_RAD53_CHEK2_ST	P30304	CDC25A	O96017	CHEK2	S107	L113F	113	Missense	distal	6	no	16.295	15.656	EPSD	TCGA;ICGC;COSMIC	8.561	Down-regulation
CAMK_RAD53_CHEK2_ST	P30304	CDC25A	O96017	CHEK2	S124	R121S	121	Missense	distal	-3	no	12.958	6.100	PhosphoSitePlus;EPSD	TCGA;ICGC;COSMIC	8.561	Loss
CAMK_RAD53_CHEK2_ST	P30304	CDC25A	O96017	CHEK2	S124	L119V	119	Missense	distal	-5	no	12.958	12.436	PhosphoSitePlus;EPSD	TCGA;ICGC;COSMIC	8.561	Down-regulation
CAMK_RAD53_CHEK2_ST	P30304	CDC25A	O96017	CHEK2	S124	P117S	117	Missense	distal	-7	no	12.958	13.194	PhosphoSitePlus;EPSD	TCGA;ICGC;COSMIC	8.561	Up-regulation
CAMK_RAD53_CHEK2_ST	P30304	CDC25A	O96017	CHEK2	S124	D125N	125	Missense	proximal	1	no	12.958	11.898	PhosphoSitePlus;EPSD	TCGA;ICGC;COSMIC	8.561	Down-regulation
CAMK_RAD53_CHEK2_ST	P30304	CDC25A	O96017	CHEK2	S124	L127V	127	Missense	distal	3	no	12.958	13.444	PhosphoSitePlus;EPSD	TCGA;ICGC;COSMIC	8.561	Up-regulation
CAMK_RAD53_CHEK2_ST	P30304	CDC25A	O96017	CHEK2	S126	R121S	121	Missense	distal	-5	no	12.035	11.739	EPSD	TCGA;ICGC;COSMIC	8.561	Down-regulation
CAMK_RAD53_CHEK2_ST	P30304	CDC25A	O96017	CHEK2	S126	L119V	119	Missense	distal	-7	no	12.035	11.320	EPSD	TCGA;ICGC;COSMIC	8.561	Down-regulation
CAMK_RAD53_CHEK2_ST	P30304	CDC25A	O96017	CHEK2	S126	D125N	125	Missense	proximal	-1	no	12.035	11.981	EPSD	TCGA;ICGC;COSMIC	8.561	Down-regulation
CAMK_RAD53_CHEK2_ST	P30304	CDC25A	O96017	CHEK2	S126	L127V	127	Missense	proximal	1	no	12.035	10.436	EPSD	TCGA;ICGC;COSMIC	8.561	Down-regulation
CAMK_RAD53_CHEK2_ST	P30304	CDC25A	O96017	CHEK2	S279	P284T	284	Missense	distal	5	no	10.580	10.688	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	8.561	Up-regulation
CAMK_RAD53_CHEK2_ST	P30304	CDC25A	O96017	CHEK2	S279	R275K	275	Missense	distal	-4	no	10.580	10.700	EPSD;PhosphoSitePlus	TCGA;ICGC	8.561	Up-regulation
CAMK_RAD53_CHEK2_ST	P30304	CDC25A	O96017	CHEK2	S293	S298N	298	Missense	distal	5	no	17.004	16.863	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	8.561	Down-regulation
CAMK_RAD53_CHEK2_ST	P30304	CDC25A	O96017	CHEK2	S505	S505N	505	Missense	central	0	yes	10.310	0.000	EPSD	TCGA;ICGC;COSMIC	8.561	Loss
CAMK_RAD53_CHEK2_ST	Q9UHR4	BAIAP2L1	O96017	CHEK2	S132	Q137K	137	Missense	distal	5	no	10.092	10.031	EPSD	TCGA;ICGC;COSMIC	8.561	Down-regulation
CAMK_RAD53_CHEK2_ST	Q9UHR4	BAIAP2L1	O96017	CHEK2	S132	E131K	131	Missense	proximal	-1	no	10.092	10.121	EPSD	TCGA;ICGC;COSMIC	8.561	Up-regulation
CAMK_RAD53_CHEK2_ST	Q9UHR4	BAIAP2L1	O96017	CHEK2	S136	Q137K	137	Missense	proximal	1	no	11.660	8.480	EPSD	TCGA;ICGC;COSMIC	8.561	Loss
CAMK_RAD53_CHEK2_ST	Q9UHR4	BAIAP2L1	O96017	CHEK2	S136	E131K	131	Missense	distal	-5	no	11.660	11.835	EPSD	TCGA;ICGC;COSMIC	8.561	Up-regulation
CAMK_RAD53_CHEK2_ST	Q9UHR4	BAIAP2L1	O96017	CHEK2	S147	R151Q	151	Missense	distal	4	no	12.676	12.740	EPSD	TCGA;ICGC;COSMIC;GDSC;CCLE	8.561	Up-regulation
CAMK_RAD53_CHEK2_ST	Q9UHR4	BAIAP2L1	O96017	CHEK2	S147	A153T	153	Missense	distal	6	no	12.676	12.822	EPSD	TCGA;ICGC;COSMIC	8.561	Up-regulation
CAMK_RAD53_CHEK2_ST	Q9UHR4	BAIAP2L1	O96017	CHEK2	T252	P253L	253	Missense	proximal	1	no	9.111	10.401	EPSD	TCGA;ICGC;COSMIC	8.561	Up-regulation
CAMK_RAD53_CHEK2_ST	Q9UHR4	BAIAP2L1	O96017	CHEK2	T294	L297F	297	Missense	distal	3	no	15.144	15.722	EPSD	TCGA	8.561	Up-regulation
CAMK_RAD53_CHEK2_ST	Q9UHR4	BAIAP2L1	O96017	CHEK2	T294	D299N	299	Missense	distal	5	no	15.144	15.240	EPSD	TCGA;ICGC;COSMIC;CCLE	8.561	Up-regulation
CAMK_RAD53_CHEK2_ST	Q9UHR4	BAIAP2L1	O96017	CHEK2	T294	G290D	290	Missense	distal	-4	no	15.144	14.005	EPSD	TCGA;ICGC;COSMIC	8.561	Down-regulation
CAMK_RAD53_CHEK2_ST	Q9UHR4	BAIAP2L1	O96017	CHEK2	S331	S329L	329	Missense	proximal	-2	no	16.079	15.794	PhosphoSitePlus	TCGA;ICGC	8.561	Down-regulation
CAMK_RAD53_CHEK2_ST	Q9UHR4	BAIAP2L1	O96017	CHEK2	S331	T334M	334	Missense	distal	3	no	16.079	16.357	PhosphoSitePlus	TCGA;ICGC;COSMIC	8.561	Up-regulation
CAMK_RAD53_CHEK2_ST	Q9UHR4	BAIAP2L1	O96017	CHEK2	S331	S331L	331	Missense	central	0	yes	16.079	0.000	PhosphoSitePlus	TCGA;ICGC;COSMIC	8.561	Loss
CAMK_RAD53_CHEK2_ST	Q9UHR4	BAIAP2L1	O96017	CHEK2	S422	V418M	418	Missense	distal	-4	no	13.937	13.952	EPSD	TCGA;ICGC;COSMIC	8.561	Up-regulation
CAMK_RAD53_CHEK2_ST	Q9UHR4	BAIAP2L1	O96017	CHEK2	S422	S422N	422	Missense	central	0	yes	13.937	0.000	EPSD	TCGA;ICGC;COSMIC	8.561	Loss
CAMK_RAD53_CHEK2_ST	Q9NRM7	LATS2	O96017	CHEK2	S172	G175R	175	Missense	distal	3	no	15.417	14.618	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	8.561	Down-regulation
CAMK_RAD53_CHEK2_ST	Q9NRM7	LATS2	O96017	CHEK2	S172	P166S	166	Missense	distal	-6	no	15.417	15.542	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	8.561	Up-regulation
CAMK_RAD53_CHEK2_ST	Q9NRM7	LATS2	O96017	CHEK2	S172	T168M	168	Missense	distal	-4	no	15.417	14.713	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	8.561	Down-regulation
CAMK_RAD53_CHEK2_ST	Q9NRM7	LATS2	O96017	CHEK2	S274	P280L	280	Missense	distal	6	no	14.952	14.805	EPSD	TCGA;ICGC;COSMIC	8.561	Down-regulation
CAMK_RAD53_CHEK2_ST	Q9NRM7	LATS2	O96017	CHEK2	S335	L331M	331	Missense	distal	-4	no	10.962	10.804	EPSD	TCGA;ICGC;COSMIC	8.561	Down-regulation
CAMK_RAD53_CHEK2_ST	Q9NRM7	LATS2	O96017	CHEK2	S408	P414L	414	Missense	distal	6	no	17.778	17.632	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	8.561	Down-regulation
CAMK_RAD53_CHEK2_ST	Q9NRM7	LATS2	O96017	CHEK2	S528	R525C	525	Missense	distal	-3	no	13.147	2.224	EPSD	TCGA;ICGC;COSMIC;GDSC;CCLE	8.561	Loss
CAMK_RAD53_CHEK2_ST	Q9NRM7	LATS2	O96017	CHEK2	S528	S528L	528	Missense	central	0	yes	13.147	0.000	EPSD	TCGA;ICGC;COSMIC	8.561	Loss
CAMK_RAD53_CHEK2_ST	Q9NRM7	LATS2	O96017	CHEK2	S835	R832G	832	Missense	distal	-3	no	14.484	8.578	EPSD	TCGA;ICGC;COSMIC	8.561	Down-regulation
CAMK_RAD53_CHEK2_ST	Q9NRM7	LATS2	O96017	CHEK2	S835	Q833H	833	Missense	proximal	-2	no	14.484	14.451	EPSD	TCGA;ICGC;COSMIC	8.561	Down-regulation
CAMK_RAD53_CHEK2_ST	Q9NRM7	LATS2	O96017	CHEK2	S835	L841F	841	Missense	distal	6	no	14.484	13.845	EPSD	TCGA;ICGC;COSMIC	8.561	Down-regulation
CAMK_RAD53_CHEK2_ST	Q9NRM7	LATS2	O96017	CHEK2	S872	L869M	869	Missense	distal	-3	no	8.535	8.946	EPSD	TCGA;ICGC	8.561	Gain
CAMK_RAD53_CHEK2_ST	P61289	PSME3	O96017	CHEK2	S17	R21Q	21	Missense	distal	4	no	11.102	11.166	EPSD	TCGA;ICGC	8.561	Up-regulation
CAMK_RAD53_CHEK2_ST	Q15717	ELAVL1	O96017	CHEK2	T32	Q29H	29	Missense	distal	-3	no	3.558	9.774	EPSD	TCGA;ICGC;COSMIC	8.561	Gain
CAMK_RAD53_CHEK2_ST	Q15717	ELAVL1	O96017	CHEK2	S48	R53W	53	Missense	distal	5	no	8.866	8.397	EPSD	TCGA;ICGC;COSMIC	8.561	Loss
CAMK_RAD53_CHEK2_ST	Q15717	ELAVL1	O96017	CHEK2	S88	T90P	90	Missense	proximal	2	no	14.048	14.120	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	8.561	Up-regulation
CAMK_RAD53_CHEK2_ST	Q15717	ELAVL1	O96017	CHEK2	S100	I103M	103	Missense	distal	3	no	10.228	9.920	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	8.561	Down-regulation
CAMK_RAD53_CHEK2_ST	Q15717	ELAVL1	O96017	CHEK2	T118	Q119H	119	Missense	proximal	1	no	14.819	11.525	PhosphoSitePlus;EPSD	TCGA;ICGC;COSMIC	8.561	Down-regulation
CAMK_RAD53_CHEK2_ST	Q15717	ELAVL1	O96017	CHEK2	T118	G112V	112	Missense	distal	-6	no	14.819	14.658	PhosphoSitePlus;EPSD	TCGA;ICGC;COSMIC	8.561	Down-regulation
CAMK_RAD53_CHEK2_ST	Q15717	ELAVL1	O96017	CHEK2	T118	V122L	122	Missense	distal	4	no	14.819	14.401	PhosphoSitePlus;EPSD	TCGA;ICGC;COSMIC	8.561	Down-regulation
CAMK_RAD53_CHEK2_ST	Q15717	ELAVL1	O96017	CHEK2	T118	P114L	114	Missense	distal	-4	no	14.819	14.042	PhosphoSitePlus;EPSD	TCGA;ICGC;COSMIC	8.561	Down-regulation
CAMK_RAD53_CHEK2_ST	P29590	PML	O96017	CHEK2	S117	R120W	120	Missense	distal	3	no	16.197	17.590	PhosphoSitePlus	TCGA;ICGC;COSMIC	8.561	Up-regulation
CAMK_RAD53_CHEK2_ST	P29590	PML	O96017	CHEK2	T198	R195C	195	Missense	distal	-3	no	12.540	1.618	EPSD	TCGA;ICGC;COSMIC	8.561	Loss
CAMK_RAD53_CHEK2_ST	P29590	PML	O96017	CHEK2	T198	R195H	195	Missense	distal	-3	no	12.540	8.807	EPSD	TCGA;ICGC;COSMIC	8.561	Down-regulation
CAMK_RAD53_CHEK2_ST	P29590	PML	O96017	CHEK2	T409	P410S	410	Missense	proximal	1	no	8.908	7.390	EPSD	TCGA;ICGC;COSMIC	8.561	Loss
CAMK_RAD53_CHEK2_ST	P29590	PML	O96017	CHEK2	T409	E405K	405	Missense	distal	-4	no	8.908	10.045	EPSD	TCGA;ICGC	8.561	Up-regulation
CAMK_RAD53_CHEK2_ST	P29590	PML	O96017	CHEK2	T409	P413L	413	Missense	distal	4	no	8.908	9.000	EPSD	TCGA;ICGC;COSMIC	8.561	Up-regulation
CAMK_RAD53_CHEK2_ST	P29590	PML	O96017	CHEK2	S512	S518L	518	Missense	distal	6	no	8.833	8.764	EPSD	TCGA;ICGC;COSMIC	8.561	Down-regulation
CAMK_RAD53_CHEK2_ST	P29590	PML	O96017	CHEK2	T513	S518L	518	Missense	distal	5	no	12.490	12.293	EPSD	TCGA;ICGC;COSMIC	8.561	Down-regulation
CAMK_RAD53_CHEK2_ST	P29590	PML	O96017	CHEK2	S518	S518L	518	Missense	central	0	yes	11.658	0.000	EPSD	TCGA;ICGC;COSMIC	8.561	Loss
CAMK_RAD53_CHEK2_ST	P29590	PML	O96017	CHEK2	S547	H544Y	544	Missense	distal	-3	no	9.517	-0.324	EPSD	TCGA;ICGC	8.561	Loss
CAMK_RAD53_CHEK2_ST	P29590	PML	O96017	CHEK2	S723	E716K	716	Missense	distal	-7	no	8.814	9.013	EPSD	TCGA;ICGC;COSMIC	8.561	Up-regulation
CAMK_RAD53_CHEK2_ST	P29590	PML	O96017	CHEK2	S723	R717C	717	Missense	distal	-6	no	8.814	8.565	EPSD	TCGA;ICGC;COSMIC	8.561	Down-regulation
CAMK_RAD53_CHEK2_ST	P21127	CDK11B	O96017	CHEK2	S38	R34C	34	Missense	distal	-4	no	9.284	8.279	EPSD	TCGA;ICGC;COSMIC;GDSC	8.561	Loss
CAMK_RAD53_CHEK2_ST	P21127	CDK11B	O96017	CHEK2	S38	R45L	45	Missense	distal	7	no	9.284	9.306	EPSD	TCGA;ICGC;COSMIC	8.561	Up-regulation
CAMK_RAD53_CHEK2_ST	P21127	CDK11B	O96017	CHEK2	S38	N37K	37	Missense	proximal	-1	no	9.284	9.019	EPSD	TCGA;ICGC	8.561	Down-regulation
CAMK_RAD53_CHEK2_ST	P21127	CDK11B	O96017	CHEK2	S72	D71H	71	Missense	proximal	-1	no	14.163	13.570	EPSD	TCGA;ICGC;COSMIC	8.561	Down-regulation
CAMK_RAD53_CHEK2_ST	P21127	CDK11B	O96017	CHEK2	S72	S72F	72	Missense	central	0	yes	14.163	0.000	EPSD	TCGA;ICGC;COSMIC	8.561	Loss
CAMK_RAD53_CHEK2_ST	P21127	CDK11B	O96017	CHEK2	S72	R76I	76	Missense	distal	4	no	14.163	14.909	EPSD	TCGA;ICGC;COSMIC	8.561	Up-regulation
CAMK_RAD53_CHEK2_ST	Q01094	E2F1	O96017	CHEK2	S313	I306V	306	Missense	distal	-7	no	10.615	11.412	EPSD	TCGA;ICGC;COSMIC	8.561	Up-regulation
CAMK_RAD53_CHEK2_ST	Q01094	E2F1	O96017	CHEK2	S352	P346L	346	Missense	distal	-6	no	9.172	8.972	EPSD	TCGA;ICGC;COSMIC	8.561	Down-regulation
CAMK_RAD53_CHEK2_ST	Q01094	E2F1	O96017	CHEK2	S364	G363R	363	Missense	proximal	-1	no	16.027	15.377	PhosphoSitePlus	TCGA;ICGC;COSMIC	8.561	Down-regulation
CAMK_RAD53_CHEK2_ST	Q01094	E2F1	O96017	CHEK2	S382	E389K	389	Missense	distal	7	no	9.663	9.648	EPSD	TCGA;ICGC;COSMIC	8.561	Down-regulation
CAMK_RAD53_CHEK2_ST	P10636	MAPT	O96017	CHEK2	T30	R23S	23	Missense	distal	-7	no	8.933	9.336	EPSD	TCGA;ICGC;COSMIC	8.561	Up-regulation
CAMK_RAD53_CHEK2_ST	P10636	MAPT	O96017	CHEK2	T30	K24I	24	Missense	distal	-6	no	8.933	8.524	EPSD	TCGA;ICGC	8.561	Loss
CAMK_RAD53_CHEK2_ST	P10636	MAPT	O96017	CHEK2	T50	D54E	54	Missense	distal	4	no	8.993	8.357	EPSD	TCGA;ICGC;COSMIC	8.561	Loss
CAMK_RAD53_CHEK2_ST	P10636	MAPT	O96017	CHEK2	T50	T52I	52	Missense	proximal	2	no	8.993	8.826	EPSD	TCGA;ICGC;COSMIC	8.561	Down-regulation
CAMK_RAD53_CHEK2_ST	P10636	MAPT	O96017	CHEK2	T50	P47S	47	Missense	distal	-3	no	8.993	7.862	EPSD	TCGA;ICGC;COSMIC	8.561	Loss
CAMK_RAD53_CHEK2_ST	P10636	MAPT	O96017	CHEK2	T50	P47L	47	Missense	distal	-3	no	8.993	7.108	EPSD	TCGA;ICGC;COSMIC	8.561	Loss
CAMK_RAD53_CHEK2_ST	P10636	MAPT	O96017	CHEK2	T50	G55R	55	Missense	distal	5	no	8.993	9.235	EPSD	TCGA;ICGC;COSMIC	8.561	Up-regulation
CAMK_RAD53_CHEK2_ST	P10636	MAPT	O96017	CHEK2	T167	R168H	168	Missense	proximal	1	no	11.981	12.282	EPSD	TCGA;ICGC;COSMIC	8.561	Up-regulation
CAMK_RAD53_CHEK2_ST	P10636	MAPT	O96017	CHEK2	T167	R168C	168	Missense	proximal	1	no	11.981	13.285	EPSD	TCGA;ICGC;COSMIC	8.561	Up-regulation
CAMK_RAD53_CHEK2_ST	P10636	MAPT	O96017	CHEK2	S171	R168H	168	Missense	distal	-3	no	11.678	7.945	EPSD	TCGA;ICGC;COSMIC	8.561	Loss
CAMK_RAD53_CHEK2_ST	P10636	MAPT	O96017	CHEK2	S171	R168C	168	Missense	distal	-3	no	11.678	0.756	EPSD	TCGA;ICGC;COSMIC	8.561	Loss
CAMK_RAD53_CHEK2_ST	P10636	MAPT	O96017	CHEK2	S214	P212L	212	Missense	proximal	-2	no	11.886	11.837	EPSD	TCGA;ICGC;COSMIC	8.561	Down-regulation
CAMK_RAD53_CHEK2_ST	P10636	MAPT	O96017	CHEK2	S214	E220K	220	Missense	distal	6	no	11.886	12.020	EPSD	TCGA;ICGC;COSMIC	8.561	Up-regulation
CAMK_RAD53_CHEK2_ST	P10636	MAPT	O96017	CHEK2	S341	E348V	348	Missense	distal	7	no	14.117	14.115	EPSD	TCGA;ICGC;COSMIC	8.561	Down-regulation
CAMK_RAD53_CHEK2_ST	P10636	MAPT	O96017	CHEK2	S341	G339R	339	Missense	proximal	-2	no	14.117	14.804	EPSD	TCGA;ICGC;COSMIC	8.561	Up-regulation
CAMK_RAD53_CHEK2_ST	P10636	MAPT	O96017	CHEK2	S341	S341F	341	Missense	central	0	yes	14.117	0.000	EPSD	TCGA;ICGC;COSMIC	8.561	Loss
CAMK_RAD53_CHEK2_ST	P10636	MAPT	O96017	CHEK2	S411	P415L	415	Missense	distal	4	no	9.726	9.818	EPSD	TCGA;ICGC;COSMIC	8.561	Up-regulation
CAMK_RAD53_CHEK2_ST	P10636	MAPT	O96017	CHEK2	S438	P436T	436	Missense	proximal	-2	no	8.462	8.718	EPSD	TCGA;ICGC;COSMIC	8.561	Gain
CAMK_RAD53_CHEK2_ST	P10636	MAPT	O96017	CHEK2	S438	V431L	431	Missense	distal	-7	no	8.462	9.177	EPSD	TCGA;ICGC;COSMIC	8.561	Gain
CAMK_RAD53_CHEK2_ST	P10636	MAPT	O96017	CHEK2	S451	E456K	456	Missense	distal	5	no	14.339	14.373	EPSD	TCGA;ICGC;COSMIC	8.561	Up-regulation
CAMK_RAD53_CHEK2_ST	P10636	MAPT	O96017	CHEK2	S451	S452C	452	Missense	proximal	1	no	14.339	16.092	EPSD	TCGA;ICGC;COSMIC	8.561	Up-regulation
CAMK_RAD53_CHEK2_ST	P10636	MAPT	O96017	CHEK2	S451	S444F	444	Missense	distal	-7	no	14.339	10.945	EPSD	TCGA;ICGC	8.561	Down-regulation
CAMK_RAD53_CHEK2_ST	P10636	MAPT	O96017	CHEK2	S451	S452Y	452	Missense	proximal	1	no	14.339	15.781	EPSD	TCGA;ICGC;COSMIC	8.561	Up-regulation
CAMK_RAD53_CHEK2_ST	P10636	MAPT	O96017	CHEK2	T492	P493Q	493	Missense	proximal	1	no	6.142	8.669	EPSD	TCGA;COSMIC	8.561	Gain
CAMK_RAD53_CHEK2_ST	P54132	BLM	O96017	CHEK2	T99	Q100H	100	Missense	proximal	1	no	10.248	6.954	EPSD	TCGA;ICGC;COSMIC	8.561	Loss
CAMK_RAD53_CHEK2_ST	P54132	BLM	O96017	CHEK2	T99	A93D	93	Missense	distal	-6	no	10.248	9.915	EPSD	TCGA;ICGC;COSMIC	8.561	Down-regulation
CAMK_RAD53_CHEK2_ST	P54132	BLM	O96017	CHEK2	T99	Q97H	97	Missense	proximal	-2	no	10.248	10.215	EPSD	TCGA;ICGC;COSMIC	8.561	Down-regulation
CAMK_RAD53_CHEK2_ST	P54132	BLM	O96017	CHEK2	S104	D110N	110	Missense	distal	6	no	11.214	11.123	EPSD	TCGA;ICGC;COSMIC	8.561	Down-regulation
CAMK_RAD53_CHEK2_ST	P54132	BLM	O96017	CHEK2	S104	Q100H	100	Missense	distal	-4	no	11.214	10.756	EPSD	TCGA;ICGC;COSMIC	8.561	Down-regulation
CAMK_RAD53_CHEK2_ST	P54132	BLM	O96017	CHEK2	S104	Q97H	97	Missense	distal	-7	no	11.214	12.245	EPSD	TCGA;ICGC;COSMIC	8.561	Up-regulation
CAMK_RAD53_CHEK2_ST	P54132	BLM	O96017	CHEK2	T182	Q184E	184	Missense	proximal	2	no	15.547	15.611	PhosphoSitePlus	TCGA;ICGC;COSMIC	8.561	Up-regulation
CAMK_RAD53_CHEK2_ST	P54132	BLM	O96017	CHEK2	T182	K188R	188	Missense	distal	6	no	15.547	15.766	PhosphoSitePlus	TCGA;ICGC;COSMIC	8.561	Up-regulation
CAMK_RAD53_CHEK2_ST	P54132	BLM	O96017	CHEK2	T182	R179I	179	Missense	distal	-3	no	15.547	6.080	PhosphoSitePlus	TCGA;ICGC;COSMIC	8.561	Loss
CAMK_RAD53_CHEK2_ST	P54132	BLM	O96017	CHEK2	T182	Q184L	184	Missense	proximal	2	no	15.547	15.487	PhosphoSitePlus	TCGA;ICGC;COSMIC	8.561	Down-regulation
CAMK_RAD53_CHEK2_ST	P54132	BLM	O96017	CHEK2	T182	S175I	175	Missense	distal	-7	no	15.547	13.089	PhosphoSitePlus	TCGA;ICGC;COSMIC	8.561	Down-regulation
CAMK_RAD53_CHEK2_ST	P54132	BLM	O96017	CHEK2	S269	E265Q	265	Missense	distal	-4	no	11.009	12.124	EPSD	TCGA;ICGC;COSMIC	8.561	Up-regulation
CAMK_RAD53_CHEK2_ST	P54132	BLM	O96017	CHEK2	S269	K273R	273	Missense	distal	4	no	11.009	10.597	EPSD	TCGA;ICGC;COSMIC	8.561	Down-regulation
CAMK_RAD53_CHEK2_ST	P54132	BLM	O96017	CHEK2	S269	K273N	273	Missense	distal	4	no	11.009	11.139	EPSD	TCGA;ICGC;COSMIC	8.561	Up-regulation
CAMK_RAD53_CHEK2_ST	P54132	BLM	O96017	CHEK2	S314	S310C	310	Missense	distal	-4	no	8.881	7.753	EPSD	TCGA;ICGC	8.561	Loss
CAMK_RAD53_CHEK2_ST	P54132	BLM	O96017	CHEK2	T412	N405S	405	Missense	distal	-7	no	7.612	8.985	EPSD	TCGA;ICGC	8.561	Gain
CAMK_RAD53_CHEK2_ST	P54132	BLM	O96017	CHEK2	S434	D433H	433	Missense	proximal	-1	no	13.150	12.556	EPSD	TCGA;ICGC;COSMIC	8.561	Down-regulation
CAMK_RAD53_CHEK2_ST	P54132	BLM	O96017	CHEK2	S434	R431K	431	Missense	distal	-3	no	13.150	8.065	EPSD	TCGA;ICGC;COSMIC	8.561	Loss
CAMK_RAD53_CHEK2_ST	P54132	BLM	O96017	CHEK2	S434	R429K	429	Missense	distal	-5	no	13.150	12.564	EPSD	TCGA;ICGC;COSMIC	8.561	Down-regulation
CAMK_RAD53_CHEK2_ST	P54132	BLM	O96017	CHEK2	S434	P438H	438	Missense	distal	4	no	13.150	13.195	EPSD	TCGA;ICGC	8.561	Up-regulation
CAMK_RAD53_CHEK2_ST	P54132	BLM	O96017	CHEK2	S434	G437V	437	Missense	distal	3	no	13.150	13.104	EPSD	TCGA;ICGC;COSMIC	8.561	Down-regulation
CAMK_RAD53_CHEK2_ST	P54132	BLM	O96017	CHEK2	S539	E546Q	546	Missense	distal	7	no	9.677	9.664	EPSD	TCGA;ICGC;COSMIC	8.561	Down-regulation
CAMK_RAD53_CHEK2_ST	P54132	BLM	O96017	CHEK2	S539	K535Q	535	Missense	distal	-4	no	9.677	9.655	EPSD	TCGA;ICGC;COSMIC	8.561	Down-regulation
CAMK_RAD53_CHEK2_ST	P54132	BLM	O96017	CHEK2	S602	L600F	600	Missense	proximal	-2	no	12.179	11.089	EPSD	TCGA;ICGC;COSMIC	8.561	Down-regulation
CAMK_RAD53_CHEK2_ST	P54132	BLM	O96017	CHEK2	S646	K653M	653	Missense	distal	7	no	13.457	13.474	EPSD	TCGA;ICGC;COSMIC	8.561	Up-regulation
CAMK_RAD53_CHEK2_ST	P54132	BLM	O96017	CHEK2	S646	L647I	647	Missense	proximal	1	no	13.457	11.273	EPSD	TCGA;COSMIC	8.561	Down-regulation
CAMK_RAD53_CHEK2_ST	P54132	BLM	O96017	CHEK2	S646	R643C	643	Missense	distal	-3	no	13.457	2.534	EPSD	TCGA;ICGC;COSMIC	8.561	Loss
CAMK_RAD53_CHEK2_ST	P54132	BLM	O96017	CHEK2	S646	K653N	653	Missense	distal	7	no	13.457	13.468	EPSD	TCGA;ICGC;COSMIC	8.561	Up-regulation
CAMK_RAD53_CHEK2_ST	P54132	BLM	O96017	CHEK2	S1197	N1194H	1194	Missense	distal	-3	no	3.623	8.587	EPSD	TCGA;ICGC;COSMIC	8.561	Gain
CAMK_RAD53_CHEK2_ST	P54132	BLM	O96017	CHEK2	S1381	Q1387E	1387	Missense	distal	6	no	9.404	9.278	EPSD	TCGA;ICGC;COSMIC	8.561	Down-regulation
CAMK_RAD53_CHEK2_ST	P54132	BLM	O96017	CHEK2	S1381	A1388T	1388	Missense	distal	7	no	9.404	9.406	EPSD	TCGA;ICGC;COSMIC	8.561	Up-regulation
CAMK_RAD53_CHEK2_ST	P54132	BLM	O96017	CHEK2	S1394	Q1387E	1387	Missense	distal	-7	no	8.758	8.958	EPSD	TCGA;ICGC;COSMIC	8.561	Up-regulation
CAMK_RAD53_CHEK2_ST	P54132	BLM	O96017	CHEK2	S1394	A1388T	1388	Missense	distal	-6	no	8.758	8.781	EPSD	TCGA;ICGC;COSMIC	8.561	Up-regulation
CAMK_RAD53_CHEK2_ST	P38398	BRCA1	O96017	CHEK2	S316	W321C	321	Missense	distal	5	no	8.320	8.614	EPSD	TCGA;COSMIC	8.561	Gain
CAMK_RAD53_CHEK2_ST	P38398	BRCA1	O96017	CHEK2	S449	R446T	446	Missense	distal	-3	no	10.890	2.347	EPSD	TCGA;COSMIC	8.561	Loss
CAMK_RAD53_CHEK2_ST	P38398	BRCA1	O96017	CHEK2	T509	E515Q	515	Missense	distal	6	no	11.278	11.404	EPSD	TCGA;COSMIC	8.561	Up-regulation
CAMK_RAD53_CHEK2_ST	P38398	BRCA1	O96017	CHEK2	T509	E515V	515	Missense	distal	6	no	11.278	11.247	EPSD	TCGA;COSMIC	8.561	Down-regulation
CAMK_RAD53_CHEK2_ST	P38398	BRCA1	O96017	CHEK2	T509	E515K	515	Missense	distal	6	no	11.278	11.412	EPSD	TCGA;COSMIC	8.561	Up-regulation
CAMK_RAD53_CHEK2_ST	P38398	BRCA1	O96017	CHEK2	T509	H513Y	513	Missense	distal	4	no	11.278	11.894	EPSD	TCGA;COSMIC	8.561	Up-regulation
CAMK_RAD53_CHEK2_ST	P38398	BRCA1	O96017	CHEK2	S510	E515Q	515	Missense	distal	5	no	12.417	12.511	EPSD	TCGA;COSMIC	8.561	Up-regulation
CAMK_RAD53_CHEK2_ST	P38398	BRCA1	O96017	CHEK2	S510	E515V	515	Missense	distal	5	no	12.417	12.395	EPSD	TCGA;COSMIC	8.561	Down-regulation
CAMK_RAD53_CHEK2_ST	P38398	BRCA1	O96017	CHEK2	S510	E515K	515	Missense	distal	5	no	12.417	12.451	EPSD	TCGA;COSMIC	8.561	Up-regulation
CAMK_RAD53_CHEK2_ST	P38398	BRCA1	O96017	CHEK2	S510	H513Y	513	Missense	distal	3	no	12.417	12.890	EPSD	TCGA;COSMIC	8.561	Up-regulation
CAMK_RAD53_CHEK2_ST	P38398	BRCA1	O96017	CHEK2	S615	R610M	610	Missense	distal	-5	no	10.681	10.231	EPSD	TCGA;COSMIC	8.561	Down-regulation
CAMK_RAD53_CHEK2_ST	P38398	BRCA1	O96017	CHEK2	S615	A622V	622	Missense	distal	7	no	10.681	10.688	EPSD	TCGA;COSMIC	8.561	Up-regulation
CAMK_RAD53_CHEK2_ST	P38398	BRCA1	O96017	CHEK2	S616	R610M	610	Missense	distal	-6	no	12.246	11.885	EPSD	TCGA;COSMIC	8.561	Down-regulation
CAMK_RAD53_CHEK2_ST	P38398	BRCA1	O96017	CHEK2	S616	A622V	622	Missense	distal	6	no	12.246	12.067	EPSD	TCGA;COSMIC	8.561	Down-regulation
CAMK_RAD53_CHEK2_ST	P38398	BRCA1	O96017	CHEK2	T617	R610M	610	Missense	distal	-7	no	9.484	8.338	EPSD	TCGA;COSMIC	8.561	Loss
CAMK_RAD53_CHEK2_ST	P38398	BRCA1	O96017	CHEK2	T617	A622V	622	Missense	distal	5	no	9.484	9.355	EPSD	TCGA;COSMIC	8.561	Down-regulation
CAMK_RAD53_CHEK2_ST	P38398	BRCA1	O96017	CHEK2	S694	K690R	690	Missense	distal	-4	no	14.634	14.514	EPSD	TCGA;COSMIC	8.561	Down-regulation
CAMK_RAD53_CHEK2_ST	P38398	BRCA1	O96017	CHEK2	S694	T688I	688	Missense	distal	-6	no	14.634	14.289	EPSD	TCGA	8.561	Down-regulation
CAMK_RAD53_CHEK2_ST	P38398	BRCA1	O96017	CHEK2	T696	K690R	690	Missense	distal	-6	no	10.674	10.764	EPSD	TCGA;COSMIC	8.561	Up-regulation
CAMK_RAD53_CHEK2_ST	P38398	BRCA1	O96017	CHEK2	T710	G707R	707	Missense	distal	-3	no	5.525	11.431	EPSD	TCGA;COSMIC	8.561	Gain
CAMK_RAD53_CHEK2_ST	P38398	BRCA1	O96017	CHEK2	S868	P871S	871	Missense	distal	3	no	10.273	10.089	EPSD	TCGA;COSMIC	8.561	Down-regulation
CAMK_RAD53_CHEK2_ST	P38398	BRCA1	O96017	CHEK2	S868	S873L	873	Missense	distal	5	no	10.273	10.075	EPSD	TCGA;COSMIC	8.561	Down-regulation
CAMK_RAD53_CHEK2_ST	P38398	BRCA1	O96017	CHEK2	S868	P875S	875	Missense	distal	7	no	10.273	10.263	EPSD	TCGA;COSMIC	8.561	Down-regulation
CAMK_RAD53_CHEK2_ST	P38398	BRCA1	O96017	CHEK2	S868	R866C	866	Missense	proximal	-2	no	10.273	9.747	EPSD	TCGA;COSMIC	8.561	Down-regulation
CAMK_RAD53_CHEK2_ST	P38398	BRCA1	O96017	CHEK2	S896	C903S	903	Missense	distal	7	no	8.599	8.582	EPSD	TCGA;COSMIC	8.561	Down-regulation
CAMK_RAD53_CHEK2_ST	P38398	BRCA1	O96017	CHEK2	S896	S889C	889	Missense	distal	-7	no	8.599	7.377	EPSD	TCGA;COSMIC	8.561	Loss
CAMK_RAD53_CHEK2_ST	P38398	BRCA1	O96017	CHEK2	S896	E902K	902	Missense	distal	6	no	8.599	8.733	EPSD	TCGA;COSMIC	8.561	Up-regulation
CAMK_RAD53_CHEK2_ST	P38398	BRCA1	O96017	CHEK2	S896	V899L	899	Missense	distal	3	no	8.599	8.113	EPSD	TCGA;COSMIC	8.561	Loss
CAMK_RAD53_CHEK2_ST	P38398	BRCA1	O96017	CHEK2	S896	K893N	893	Missense	distal	-3	no	8.599	4.986	EPSD	TCGA;COSMIC	8.561	Loss
CAMK_RAD53_CHEK2_ST	P38398	BRCA1	O96017	CHEK2	S988	P982L	982	Missense	distal	-6	no	10.468	10.267	PhosphoSitePlus	TCGA;COSMIC	8.561	Down-regulation
CAMK_RAD53_CHEK2_ST	P38398	BRCA1	O96017	CHEK2	S988	P985L	985	Missense	distal	-3	no	10.468	8.583	PhosphoSitePlus	TCGA;COSMIC	8.561	Down-regulation
CAMK_RAD53_CHEK2_ST	P38398	BRCA1	O96017	CHEK2	S988	K991Q	991	Missense	distal	3	no	10.468	9.275	PhosphoSitePlus	TCGA;COSMIC	8.561	Down-regulation
CAMK_RAD53_CHEK2_ST	P38398	BRCA1	O96017	CHEK2	S1009	E1013Q	1013	Missense	distal	4	no	9.311	9.110	EPSD	TCGA	8.561	Down-regulation
CAMK_RAD53_CHEK2_ST	P38398	BRCA1	O96017	CHEK2	S1009	N1002K	1002	Missense	distal	-7	no	9.311	10.014	EPSD	TCGA	8.561	Up-regulation
CAMK_RAD53_CHEK2_ST	P38398	BRCA1	O96017	CHEK2	S1245	T1242A	1242	Missense	distal	-3	no	5.785	8.614	EPSD	TCGA;COSMIC	8.561	Gain
CAMK_RAD53_CHEK2_ST	P38398	BRCA1	O96017	CHEK2	T1246	V1247I	1247	Missense	proximal	1	no	11.821	11.235	EPSD	TCGA;COSMIC	8.561	Down-regulation
CAMK_RAD53_CHEK2_ST	P38398	BRCA1	O96017	CHEK2	T1246	T1242A	1242	Missense	distal	-4	no	11.821	12.600	EPSD	TCGA;COSMIC	8.561	Up-regulation
CAMK_RAD53_CHEK2_ST	P38398	BRCA1	O96017	CHEK2	T1246	H1244N	1244	Missense	proximal	-2	no	11.821	11.510	EPSD	TCGA;COSMIC	8.561	Down-regulation
CAMK_RAD53_CHEK2_ST	P38398	BRCA1	O96017	CHEK2	T1246	E1250K	1250	Missense	distal	4	no	11.821	11.968	EPSD	TCGA;COSMIC;GDSC	8.561	Up-regulation
CAMK_RAD53_CHEK2_ST	P38398	BRCA1	O96017	CHEK2	T1312	N1309H	1309	Missense	distal	-3	no	7.627	12.591	EPSD	TCGA;COSMIC	8.561	Gain
CAMK_RAD53_CHEK2_ST	P38398	BRCA1	O96017	CHEK2	T1675	R1670T	1670	Missense	distal	-5	no	10.864	10.985	EPSD	TCGA;COSMIC	8.561	Up-regulation
CAMK_RAD53_CHEK2_ST	P40337	VHL	O96017	CHEK2	S72	S65W	65	Missense	distal	-7	no	15.594	12.708	EPSD	TCGA;ICGC;COSMIC;CCLE	8.561	Down-regulation
CAMK_RAD53_CHEK2_ST	P40337	VHL	O96017	CHEK2	S72	V74D	74	Missense	proximal	2	no	15.594	15.482	EPSD	TCGA;ICGC;COSMIC	8.561	Down-regulation
CAMK_RAD53_CHEK2_ST	P40337	VHL	O96017	CHEK2	S72	N78D	78	Missense	distal	6	no	15.594	15.685	EPSD	TCGA;ICGC;COSMIC	8.561	Up-regulation
CAMK_RAD53_CHEK2_ST	P40337	VHL	O96017	CHEK2	S72	N78Y	78	Missense	distal	6	no	15.594	15.504	EPSD	TCGA;ICGC;COSMIC	8.561	Down-regulation
CAMK_RAD53_CHEK2_ST	P40337	VHL	O96017	CHEK2	S72	R79G	79	Missense	distal	7	no	15.594	15.604	EPSD	TCGA;ICGC;COSMIC	8.561	Up-regulation
CAMK_RAD53_CHEK2_ST	P40337	VHL	O96017	CHEK2	S111	R113Q	113	Missense	proximal	2	no	14.752	14.548	PhosphoSitePlus	TCGA;ICGC;COSMIC	8.561	Down-regulation
CAMK_RAD53_CHEK2_ST	P40337	VHL	O96017	CHEK2	S111	H115N	115	Missense	distal	4	no	14.752	15.068	PhosphoSitePlus	TCGA;COSMIC	8.561	Up-regulation
CAMK_RAD53_CHEK2_ST	P40337	VHL	O96017	CHEK2	S111	R107P	107	Missense	distal	-4	no	14.752	14.166	PhosphoSitePlus	TCGA;ICGC;COSMIC	8.561	Down-regulation
CAMK_RAD53_CHEK2_ST	P40337	VHL	O96017	CHEK2	S111	L118P	118	Missense	distal	7	no	14.752	14.738	PhosphoSitePlus	TCGA;ICGC;COSMIC	8.561	Down-regulation
CAMK_RAD53_CHEK2_ST	P40337	VHL	O96017	CHEK2	S111	H110P	110	Missense	proximal	-1	no	14.752	14.626	PhosphoSitePlus	TCGA;ICGC;COSMIC;GDSC	8.561	Down-regulation
CAMK_RAD53_CHEK2_ST	P40337	VHL	O96017	CHEK2	S111	H115Y	115	Missense	distal	4	no	14.752	15.369	PhosphoSitePlus	TCGA;COSMIC;GDSC;CCLE	8.561	Up-regulation
CAMK_RAD53_CHEK2_ST	P40337	VHL	O96017	CHEK2	S111	S111N	111	Missense	central	0	yes	14.752	0.000	PhosphoSitePlus	TCGA;ICGC;COSMIC;CCLE	8.561	Loss
CAMK_RAD53_CHEK2_ST	P40337	VHL	O96017	CHEK2	S111	W117C	117	Missense	distal	6	no	14.752	15.424	PhosphoSitePlus	TCGA;ICGC;COSMIC	8.561	Up-regulation
CAMK_RAD53_CHEK2_ST	P40337	VHL	O96017	CHEK2	S111	L118F	118	Missense	distal	7	no	14.752	14.769	PhosphoSitePlus	TCGA;ICGC;COSMIC	8.561	Up-regulation
CAMK_RAD53_CHEK2_ST	P40337	VHL	O96017	CHEK2	S168	R167G	167	Missense	proximal	-1	no	7.952	8.602	EPSD	TCGA;COSMIC	8.561	Gain
CAMK_RAD53_CHEK2_ST	P40337	VHL	O96017	CHEK2	S168	R167W	167	Missense	proximal	-1	no	7.952	9.159	EPSD	TCGA;ICGC;COSMIC	8.561	Gain
CAMK_RAD53_CHEK2_ST	Q13263	TRIM28	O96017	CHEK2	S285	S279N	279	Missense	distal	-6	no	11.409	11.040	EPSD	TCGA;COSMIC	8.561	Down-regulation
CAMK_RAD53_CHEK2_ST	Q13263	TRIM28	O96017	CHEK2	S285	V287I	287	Missense	proximal	2	no	11.409	11.321	EPSD	TCGA;ICGC;COSMIC	8.561	Down-regulation
CAMK_RAD53_CHEK2_ST	Q13263	TRIM28	O96017	CHEK2	S285	Q288R	288	Missense	distal	3	no	11.409	11.801	EPSD	TCGA;ICGC;COSMIC	8.561	Up-regulation
CAMK_RAD53_CHEK2_ST	Q13263	TRIM28	O96017	CHEK2	T415	P422S	422	Missense	distal	7	no	11.020	11.010	EPSD	TCGA;ICGC;COSMIC	8.561	Down-regulation
CAMK_RAD53_CHEK2_ST	Q13263	TRIM28	O96017	CHEK2	T415	E411D	411	Missense	distal	-4	no	11.020	9.943	EPSD	TCGA;ICGC	8.561	Down-regulation
CAMK_RAD53_CHEK2_ST	Q13263	TRIM28	O96017	CHEK2	T415	R412H	412	Missense	distal	-3	no	11.020	7.287	EPSD	TCGA;ICGC	8.561	Loss
CAMK_RAD53_CHEK2_ST	Q13263	TRIM28	O96017	CHEK2	S417	P422S	422	Missense	distal	5	no	9.214	9.345	EPSD	TCGA;ICGC;COSMIC	8.561	Up-regulation
CAMK_RAD53_CHEK2_ST	Q13263	TRIM28	O96017	CHEK2	S417	E411D	411	Missense	distal	-6	no	9.214	8.896	EPSD	TCGA;ICGC	8.561	Down-regulation
CAMK_RAD53_CHEK2_ST	Q13263	TRIM28	O96017	CHEK2	S417	R412H	412	Missense	distal	-5	no	9.214	9.084	EPSD	TCGA;ICGC	8.561	Down-regulation
CAMK_RAD53_CHEK2_ST	Q13263	TRIM28	O96017	CHEK2	S473	G480S	480	Missense	distal	7	no	14.111	14.098	PhosphoSitePlus	TCGA;ICGC	8.561	Down-regulation
CAMK_RAD53_CHEK2_ST	Q13263	TRIM28	O96017	CHEK2	S473	R472H	472	Missense	proximal	-1	no	14.111	14.366	PhosphoSitePlus	TCGA;COSMIC	8.561	Up-regulation
CAMK_RAD53_CHEK2_ST	Q13263	TRIM28	O96017	CHEK2	S489	D496N	496	Missense	distal	7	no	8.571	8.559	EPSD	TCGA;ICGC	8.561	Loss
CAMK_RAD53_CHEK2_ST	Q13263	TRIM28	O96017	CHEK2	S489	E491D	491	Missense	proximal	2	no	8.571	8.380	EPSD	TCGA;COSMIC	8.561	Loss
CAMK_RAD53_CHEK2_ST	Q13263	TRIM28	O96017	CHEK2	S489	R492C	492	Missense	distal	3	no	8.571	8.866	EPSD	TCGA;ICGC;COSMIC;GDSC;CCLE	8.561	Up-regulation
CAMK_RAD53_CHEK2_ST	Q13263	TRIM28	O96017	CHEK2	S489	R483H	483	Missense	distal	-6	no	8.571	8.530	EPSD	TCGA;ICGC;COSMIC	8.561	Loss
CAMK_RAD53_CHEK2_ST	Q13263	TRIM28	O96017	CHEK2	T541	P534S	534	Missense	distal	-7	no	10.217	10.453	EPSD	TCGA;ICGC	8.561	Up-regulation
CAMK_RAD53_CHEK2_ST	Q13263	TRIM28	O96017	CHEK2	S594	P590S	590	Missense	distal	-4	no	11.064	11.773	EPSD	TCGA;ICGC;COSMIC	8.561	Up-regulation
CAMK_RAD53_CHEK2_ST	Q13263	TRIM28	O96017	CHEK2	S594	A587V	587	Missense	distal	-7	no	11.064	10.468	EPSD	TCGA;ICGC;COSMIC	8.561	Down-regulation
CAMK_RAD53_CHEK2_ST	Q13263	TRIM28	O96017	CHEK2	S594	S598G	598	Missense	distal	4	no	11.064	11.753	EPSD	TCGA	8.561	Up-regulation
CAMK_RAD53_CHEK2_ST	Q13263	TRIM28	O96017	CHEK2	S594	R591H	591	Missense	distal	-3	no	11.064	7.331	EPSD	TCGA;ICGC	8.561	Loss
CAMK_RAD53_CHEK2_ST	Q13263	TRIM28	O96017	CHEK2	S598	S598G	598	Missense	central	0	yes	10.812	0.000	EPSD	TCGA	8.561	Loss
CAMK_RAD53_CHEK2_ST	Q13263	TRIM28	O96017	CHEK2	S598	R591H	591	Missense	distal	-7	no	10.812	11.177	EPSD	TCGA;ICGC	8.561	Up-regulation
CAMK_RAD53_CHEK2_ST	Q13263	TRIM28	O96017	CHEK2	S683	D688Y	688	Missense	distal	5	no	10.140	10.063	EPSD	TCGA;ICGC;COSMIC	8.561	Down-regulation
CAMK_RAD53_CHEK2_ST	Q13263	TRIM28	O96017	CHEK2	S757	Y755C	755	Missense	proximal	-2	no	8.330	9.223	EPSD	TCGA;ICGC;COSMIC	8.561	Gain
CAMK_RAD53_CHEK2_ST	Q13263	TRIM28	O96017	CHEK2	S824	S823I	823	Missense	proximal	-1	no	8.389	8.880	EPSD	TCGA;ICGC	8.561	Gain
CAMK_RAD53_CHEK2_ST	O15151	MDM4	O96017	CHEK2	S127	Q124H	124	Missense	distal	-3	no	4.067	10.283	EPSD	TCGA;COSMIC	8.561	Gain
CAMK_RAD53_CHEK2_ST	O15151	MDM4	O96017	CHEK2	T150	P156S	156	Missense	distal	6	no	17.703	17.625	EPSD	TCGA;ICGC;COSMIC	8.561	Down-regulation
CAMK_RAD53_CHEK2_ST	O15151	MDM4	O96017	CHEK2	T150	D154N	154	Missense	distal	4	no	17.703	17.343	EPSD	TCGA;ICGC;COSMIC;CCLE	8.561	Down-regulation
CAMK_RAD53_CHEK2_ST	O15151	MDM4	O96017	CHEK2	T151	P156S	156	Missense	distal	5	no	8.770	8.902	EPSD	TCGA;ICGC;COSMIC	8.561	Up-regulation
CAMK_RAD53_CHEK2_ST	O15151	MDM4	O96017	CHEK2	T151	D154N	154	Missense	distal	3	no	8.770	8.301	EPSD	TCGA;ICGC;COSMIC;CCLE	8.561	Loss
CAMK_RAD53_CHEK2_ST	O15151	MDM4	O96017	CHEK2	S342	T338P	338	Missense	distal	-4	no	10.639	10.869	PhosphoSitePlus;EPSD	TCGA;COSMIC	8.561	Up-regulation
CAMK_RAD53_CHEK2_ST	O15151	MDM4	O96017	CHEK2	S367	V371I	371	Missense	distal	4	no	16.057	16.112	EPSD;PhosphoSitePlus	TCGA;COSMIC	8.561	Up-regulation
CAMK_RAD53_CHEK2_ST	O15151	MDM4	O96017	CHEK2	S367	P369S	369	Missense	proximal	2	no	16.057	16.110	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	8.561	Up-regulation
CAMK_RAD53_CHEK2_ST	P30307	CDC25C	O96017	CHEK2	S38	D36Y	36	Missense	proximal	-2	no	15.082	14.627	EPSD	TCGA;ICGC	8.561	Down-regulation
CAMK_RAD53_CHEK2_ST	P30307	CDC25C	O96017	CHEK2	S214	P215Q	215	Missense	proximal	1	no	6.934	9.461	EPSD	TCGA;ICGC;COSMIC	8.561	Gain
CAMK_RAD53_CHEK2_ST	P30307	CDC25C	O96017	CHEK2	S216	N222K	222	Missense	distal	6	no	15.096	15.446	PhosphoSitePlus	TCGA;ICGC;COSMIC	8.561	Up-regulation
CAMK_RAD53_CHEK2_ST	P30307	CDC25C	O96017	CHEK2	S216	P215Q	215	Missense	proximal	-1	no	15.096	14.988	PhosphoSitePlus	TCGA;ICGC;COSMIC	8.561	Down-regulation
CAMK_RAD53_CHEK2_ST	P30307	CDC25C	O96017	CHEK2	S216	R213H	213	Missense	distal	-3	no	15.096	11.364	PhosphoSitePlus	TCGA;ICGC;COSMIC	8.561	Down-regulation
CAMK_RAD53_CHEK2_ST	P30307	CDC25C	O96017	CHEK2	S216	R213C	213	Missense	distal	-3	no	15.096	4.174	PhosphoSitePlus	TCGA;ICGC;COSMIC	8.561	Loss
CAMK_RAD53_CHEK2_ST	P30307	CDC25C	O96017	CHEK2	S216	S214F	214	Missense	proximal	-2	no	15.096	13.721	PhosphoSitePlus	TCGA;ICGC;COSMIC	8.561	Down-regulation
CAMK_RAD53_CHEK2_ST	P30307	CDC25C	O96017	CHEK2	S216	L221S	221	Missense	distal	5	no	15.096	15.293	PhosphoSitePlus	TCGA;ICGC;COSMIC	8.561	Up-regulation
CAMK_RAD53_CHEK2_ST	P30307	CDC25C	O96017	CHEK2	S216	P218S	218	Missense	proximal	2	no	15.096	15.149	PhosphoSitePlus	TCGA;ICGC	8.561	Up-regulation
CAMK_RAD53_CHEK2_ST	P30307	CDC25C	O96017	CHEK2	S263	S263F	263	Missense	central	0	yes	11.758	0.000	EPSD	TCGA;ICGC;COSMIC	8.561	Loss
CAMK_RAD53_CHEK2_ST	P06400	RB1	O96017	CHEK2	S350	S350I	350	Missense	central	0	yes	8.629	0.000	EPSD	TCGA;ICGC;COSMIC;GDSC	8.561	Loss
CAMK_RAD53_CHEK2_ST	P06400	RB1	O96017	CHEK2	S618	S624Y	624	Missense	distal	6	no	11.075	10.480	EPSD	TCGA;ICGC;COSMIC	8.561	Down-regulation
CAMK_RAD53_CHEK2_ST	P06400	RB1	O96017	CHEK2	S618	R621H	621	Missense	distal	3	no	11.075	11.481	EPSD	TCGA;ICGC;COSMIC;CCLE	8.561	Up-regulation
CAMK_RAD53_CHEK2_ST	P06400	RB1	O96017	CHEK2	T619	S624Y	624	Missense	distal	5	no	10.804	10.490	EPSD	TCGA;ICGC;COSMIC	8.561	Down-regulation
CAMK_RAD53_CHEK2_ST	P06400	RB1	O96017	CHEK2	T619	R621H	621	Missense	proximal	2	no	10.804	10.780	EPSD	TCGA;ICGC;COSMIC;CCLE	8.561	Down-regulation
CAMK_RAD53_CHEK2_ST	P06400	RB1	O96017	CHEK2	S624	Q631H	631	Missense	distal	7	no	14.601	14.602	EPSD	TCGA;ICGC;COSMIC	8.561	Up-regulation
CAMK_RAD53_CHEK2_ST	P06400	RB1	O96017	CHEK2	S624	S624Y	624	Missense	central	0	yes	14.601	0.000	EPSD	TCGA;ICGC;COSMIC	8.561	Loss
CAMK_RAD53_CHEK2_ST	P06400	RB1	O96017	CHEK2	S624	R621H	621	Missense	distal	-3	no	14.601	10.868	EPSD	TCGA;ICGC;COSMIC;CCLE	8.561	Down-regulation
CAMK_RAD53_CHEK2_ST	P06400	RB1	O96017	CHEK2	T630	Q631H	631	Missense	proximal	1	no	8.764	5.470	EPSD	TCGA;ICGC;COSMIC	8.561	Loss
CAMK_RAD53_CHEK2_ST	P06400	RB1	O96017	CHEK2	T630	S624Y	624	Missense	distal	-6	no	8.764	8.168	EPSD	TCGA;ICGC;COSMIC	8.561	Loss
CAMK_RAD53_CHEK2_ST	P06400	RB1	O96017	CHEK2	S634	Q631H	631	Missense	distal	-3	no	3.546	9.763	EPSD	TCGA;ICGC;COSMIC	8.561	Gain
CAMK_RAD53_CHEK2_ST	P06400	RB1	O96017	CHEK2	T778	I782M	782	Missense	distal	4	no	11.420	11.199	EPSD	TCGA;ICGC;COSMIC	8.561	Down-regulation
CAMK_RAD53_CHEK2_ST	P06400	RB1	O96017	CHEK2	S780	I782M	782	Missense	proximal	2	no	9.151	9.156	EPSD	TCGA;ICGC;COSMIC	8.561	Up-regulation
CAMK_RAD53_CHEK2_ST	P06400	RB1	O96017	CHEK2	S780	R787Q	787	Missense	distal	7	no	9.151	9.157	EPSD	TCGA;ICGC;COSMIC	8.561	Up-regulation
CAMK_RAD53_CHEK2_ST	P06400	RB1	O96017	CHEK2	T823	P827S	827	Missense	distal	4	no	9.137	8.909	EPSD	TCGA;ICGC;COSMIC	8.561	Down-regulation
CAMK_RAD53_CHEK2_ST	O60673	REV3L	O96017	CHEK2	S423	E429G	429	Missense	distal	6	no	8.976	9.036	EPSD	TCGA;ICGC;COSMIC	8.561	Up-regulation
CAMK_RAD53_CHEK2_ST	O60673	REV3L	O96017	CHEK2	S423	G425R	425	Missense	proximal	2	no	8.976	9.056	EPSD	TCGA;ICGC;COSMIC	8.561	Up-regulation
CAMK_RAD53_CHEK2_ST	O60673	REV3L	O96017	CHEK2	S435	E429G	429	Missense	distal	-6	no	12.643	12.615	EPSD	TCGA;ICGC;COSMIC	8.561	Down-regulation
CAMK_RAD53_CHEK2_ST	O60673	REV3L	O96017	CHEK2	S435	C437Y	437	Missense	proximal	2	no	12.643	12.352	EPSD	TCGA;ICGC;COSMIC	8.561	Down-regulation
CAMK_RAD53_CHEK2_ST	O60673	REV3L	O96017	CHEK2	S435	R438H	438	Missense	distal	3	no	12.643	13.049	EPSD	TCGA;ICGC;COSMIC	8.561	Up-regulation
CAMK_RAD53_CHEK2_ST	O60673	REV3L	O96017	CHEK2	S435	G441R	441	Missense	distal	6	no	12.643	12.935	EPSD	TCGA;ICGC;COSMIC	8.561	Up-regulation
CAMK_RAD53_CHEK2_ST	O60673	REV3L	O96017	CHEK2	S470	M463I	463	Missense	distal	-7	no	11.540	10.630	EPSD	TCGA;ICGC;COSMIC	8.561	Down-regulation
CAMK_RAD53_CHEK2_ST	O60673	REV3L	O96017	CHEK2	S470	S466G	466	Missense	distal	-4	no	11.540	10.461	EPSD	TCGA;ICGC;COSMIC	8.561	Down-regulation
CAMK_RAD53_CHEK2_ST	O60673	REV3L	O96017	CHEK2	S470	D474N	474	Missense	distal	4	no	11.540	11.180	EPSD	TCGA;ICGC	8.561	Down-regulation
CAMK_RAD53_CHEK2_ST	O60673	REV3L	O96017	CHEK2	S545	T550A	550	Missense	distal	5	no	10.208	10.209	EPSD	TCGA;ICGC;COSMIC	8.561	Up-regulation
CAMK_RAD53_CHEK2_ST	O60673	REV3L	O96017	CHEK2	S968	S968Y	968	Missense	central	0	yes	14.181	0.000	EPSD	TCGA;ICGC;COSMIC	8.561	Loss
CAMK_RAD53_CHEK2_ST	O60673	REV3L	O96017	CHEK2	S968	P973T	973	Missense	distal	5	no	14.181	14.289	EPSD	TCGA;ICGC;COSMIC	8.561	Up-regulation
CAMK_RAD53_CHEK2_ST	O60673	REV3L	O96017	CHEK2	S968	K966T	966	Missense	proximal	-2	no	14.181	14.189	EPSD	TCGA;ICGC;COSMIC	8.561	Up-regulation
CAMK_RAD53_CHEK2_ST	O60673	REV3L	O96017	CHEK2	S1075	S1075F	1075	Missense	central	0	yes	19.271	0.000	PhosphoSitePlus	TCGA;ICGC;COSMIC	8.561	Loss
CAMK_RAD53_CHEK2_ST	O60673	REV3L	O96017	CHEK2	S1075	S1081L	1081	Missense	distal	6	no	19.271	19.202	PhosphoSitePlus	TCGA;COSMIC;GDSC;CCLE	8.561	Down-regulation
CAMK_RAD53_CHEK2_ST	O60673	REV3L	O96017	CHEK2	S1075	R1072I	1072	Missense	distal	-3	no	19.271	9.803	PhosphoSitePlus	TCGA;ICGC;COSMIC	8.561	Down-regulation
CAMK_RAD53_CHEK2_ST	O60673	REV3L	O96017	CHEK2	S1123	S1124F	1124	Missense	proximal	1	no	5.778	10.534	EPSD	TCGA;ICGC;COSMIC	8.561	Gain
CAMK_RAD53_CHEK2_ST	O60673	REV3L	O96017	CHEK2	S1130	P1125A	1125	Missense	distal	-5	no	16.877	16.218	EPSD	TCGA;ICGC;COSMIC	8.561	Down-regulation
CAMK_RAD53_CHEK2_ST	O60673	REV3L	O96017	CHEK2	S1130	R1127C	1127	Missense	distal	-3	no	16.877	5.954	EPSD	TCGA	8.561	Loss
CAMK_RAD53_CHEK2_ST	O60673	REV3L	O96017	CHEK2	S1130	R1135T	1135	Missense	distal	5	no	16.877	16.793	EPSD	TCGA;ICGC;COSMIC	8.561	Down-regulation
CAMK_RAD53_CHEK2_ST	O60673	REV3L	O96017	CHEK2	S1130	S1124F	1124	Missense	distal	-6	no	16.877	16.187	EPSD	TCGA;ICGC;COSMIC	8.561	Down-regulation
CAMK_RAD53_CHEK2_ST	O60673	REV3L	O96017	CHEK2	T1224	K1217T	1217	Missense	distal	-7	no	16.756	16.580	EPSD	TCGA;ICGC;COSMIC	8.561	Down-regulation
CAMK_RAD53_CHEK2_ST	O60673	REV3L	O96017	CHEK2	S1258	F1251C	1251	Missense	distal	-7	no	7.749	9.922	EPSD	TCGA;ICGC;COSMIC	8.561	Gain
CAMK_RAD53_CHEK2_ST	O60673	REV3L	O96017	CHEK2	S1515	A1519V	1519	Missense	distal	4	no	10.333	10.666	EPSD	TCGA;ICGC;COSMIC	8.561	Up-regulation
CAMK_RAD53_CHEK2_ST	O60673	REV3L	O96017	CHEK2	S1515	G1521C	1521	Missense	distal	6	no	10.333	10.420	EPSD	TCGA	8.561	Up-regulation
CAMK_RAD53_CHEK2_ST	O60673	REV3L	O96017	CHEK2	S1515	R1512Q	1512	Missense	distal	-3	no	10.333	0.384	EPSD	TCGA;ICGC;COSMIC	8.561	Loss
CAMK_RAD53_CHEK2_ST	O60673	REV3L	O96017	CHEK2	S1515	Q1508R	1508	Missense	distal	-7	no	10.333	10.999	EPSD	TCGA;ICGC;COSMIC	8.561	Up-regulation
CAMK_RAD53_CHEK2_ST	O60673	REV3L	O96017	CHEK2	S1515	A1519S	1519	Missense	distal	4	no	10.333	9.928	EPSD	TCGA;ICGC	8.561	Down-regulation
CAMK_RAD53_CHEK2_ST	O60673	REV3L	O96017	CHEK2	S1576	R1573W	1573	Missense	distal	-3	no	11.716	-1.512	EPSD	TCGA;ICGC;COSMIC	8.561	Loss
CAMK_RAD53_CHEK2_ST	O60673	REV3L	O96017	CHEK2	S1576	S1576L	1576	Missense	central	0	yes	11.716	0.000	EPSD	TCGA;ICGC;COSMIC	8.561	Loss
CAMK_RAD53_CHEK2_ST	O60673	REV3L	O96017	CHEK2	S1576	R1573Q	1573	Missense	distal	-3	no	11.716	1.767	EPSD	TCGA;ICGC;COSMIC;CCLE	8.561	Loss
CAMK_RAD53_CHEK2_ST	O60673	REV3L	O96017	CHEK2	T1578	R1573W	1573	Missense	distal	-5	no	11.860	10.504	EPSD	TCGA;ICGC;COSMIC	8.561	Down-regulation
CAMK_RAD53_CHEK2_ST	O60673	REV3L	O96017	CHEK2	T1578	R1584Q	1584	Missense	distal	6	no	11.860	11.634	EPSD	TCGA;ICGC;COSMIC	8.561	Down-regulation
CAMK_RAD53_CHEK2_ST	O60673	REV3L	O96017	CHEK2	T1578	S1576L	1576	Missense	proximal	-2	no	11.860	11.575	EPSD	TCGA;ICGC;COSMIC	8.561	Down-regulation
CAMK_RAD53_CHEK2_ST	O60673	REV3L	O96017	CHEK2	T1578	R1573Q	1573	Missense	distal	-5	no	11.860	11.983	EPSD	TCGA;ICGC;COSMIC;CCLE	8.561	Up-regulation
CAMK_RAD53_CHEK2_ST	O60673	REV3L	O96017	CHEK2	T1722	E1729Q	1729	Missense	distal	7	no	12.721	12.708	EPSD	TCGA;ICGC;COSMIC	8.561	Down-regulation
CAMK_RAD53_CHEK2_ST	O60673	REV3L	O96017	CHEK2	T1722	W1717C	1717	Missense	distal	-5	no	12.721	13.929	EPSD	TCGA;ICGC;COSMIC	8.561	Up-regulation
CAMK_RAD53_CHEK2_ST	O60673	REV3L	O96017	CHEK2	T1722	R1719I	1719	Missense	distal	-3	no	12.721	3.253	EPSD	TCGA;ICGC	8.561	Loss
CAMK_RAD53_CHEK2_ST	O60673	REV3L	O96017	CHEK2	T1722	S1724R	1724	Missense	proximal	2	no	12.721	12.737	EPSD	TCGA;ICGC;COSMIC	8.561	Up-regulation
CAMK_RAD53_CHEK2_ST	O60673	REV3L	O96017	CHEK2	T1722	E1726D	1726	Missense	distal	4	no	12.721	13.357	EPSD	TCGA;ICGC;COSMIC	8.561	Up-regulation
CAMK_RAD53_CHEK2_ST	O60673	REV3L	O96017	CHEK2	S1757	S1761C	1761	Missense	distal	4	no	14.520	14.972	EPSD	TCGA;ICGC;COSMIC	8.561	Up-regulation
CAMK_RAD53_CHEK2_ST	O60673	REV3L	O96017	CHEK2	S1757	D1760V	1760	Missense	distal	3	no	14.520	14.151	EPSD	TCGA;ICGC;COSMIC	8.561	Down-regulation
CAMK_RAD53_CHEK2_ST	O60673	REV3L	O96017	CHEK2	S1757	R1754Q	1754	Missense	distal	-3	no	14.520	4.571	EPSD	TCGA;ICGC;COSMIC	8.561	Loss
CAMK_RAD53_CHEK2_ST	O60673	REV3L	O96017	CHEK2	S1757	S1761Y	1761	Missense	distal	4	no	14.520	15.409	EPSD	TCGA;ICGC;COSMIC	8.561	Up-regulation
CAMK_RAD53_CHEK2_ST	O60673	REV3L	O96017	CHEK2	S1967	Q1961H	1961	Missense	distal	-6	no	11.688	11.747	EPSD	TCGA;ICGC;COSMIC	8.561	Up-regulation
CAMK_RAD53_CHEK2_ST	O60673	REV3L	O96017	CHEK2	S2147	D2142N	2142	Missense	distal	-5	no	12.232	12.004	EPSD	TCGA;ICGC;COSMIC	8.561	Down-regulation
CAMK_RAD53_CHEK2_ST	O60673	REV3L	O96017	CHEK2	T2187	A2189T	2189	Missense	proximal	2	no	9.802	9.727	EPSD	TCGA;ICGC;COSMIC	8.561	Down-regulation
CAMK_RAD53_CHEK2_ST	O60673	REV3L	O96017	CHEK2	S2430	R2431Q	2431	Missense	proximal	1	no	10.190	13.785	EPSD	TCGA;ICGC;COSMIC	8.561	Up-regulation
CAMK_RAD53_CHEK2_ST	O60673	REV3L	O96017	CHEK2	S2430	D2435A	2435	Missense	distal	5	no	10.190	10.404	EPSD	TCGA;ICGC	8.561	Up-regulation
CAMK_RAD53_CHEK2_ST	O60673	REV3L	O96017	CHEK2	S2430	R2427W	2427	Missense	distal	-3	no	10.190	-3.039	EPSD	TCGA;ICGC;COSMIC	8.561	Loss
CAMK_RAD53_CHEK2_ST	O60673	REV3L	O96017	CHEK2	S2714	D2718N	2718	Missense	distal	4	no	9.330	8.971	EPSD	TCGA;ICGC;COSMIC	8.561	Down-regulation
CAMK_RAD53_CHEK2_ST	O60673	REV3L	O96017	CHEK2	S2714	R2715Q	2715	Missense	proximal	1	no	9.330	12.925	EPSD	TCGA;ICGC;COSMIC;CCLE	8.561	Up-regulation
CAMK_RAD53_CHEK2_ST	O60673	REV3L	O96017	CHEK2	S2714	A2719V	2719	Missense	distal	5	no	9.330	9.201	EPSD	TCGA;ICGC;COSMIC;GDSC;CCLE	8.561	Down-regulation
CAMK_RAD53_CHEK2_ST	O60673	REV3L	O96017	CHEK2	S2714	R2720H	2720	Missense	distal	6	no	9.330	9.416	EPSD	TCGA;ICGC;COSMIC	8.561	Up-regulation
CAMK_RAD53_CHEK2_ST	O60673	REV3L	O96017	CHEK2	S2884	D2882H	2882	Missense	proximal	-2	no	11.433	12.051	EPSD	TCGA;ICGC;COSMIC	8.561	Up-regulation
CAMK_RAD53_CHEK2_ST	O60673	REV3L	O96017	CHEK2	S2884	K2887Q	2887	Missense	distal	3	no	11.433	10.240	EPSD	TCGA;ICGC;COSMIC	8.561	Down-regulation
CAMK_RAD53_CHEK2_ST	O60673	REV3L	O96017	CHEK2	S2884	E2879Q	2879	Missense	distal	-5	no	11.433	12.316	EPSD	TCGA;ICGC;COSMIC	8.561	Up-regulation
CAMK_RAD53_CHEK2_ST	O60673	REV3L	O96017	CHEK2	S2884	T2880M	2880	Missense	distal	-4	no	11.433	10.730	EPSD	TCGA;ICGC;COSMIC	8.561	Down-regulation
CAMK_RAD53_CHEK2_ST	O60673	REV3L	O96017	CHEK2	S2884	E2879K	2879	Missense	distal	-5	no	11.433	11.608	EPSD	TCGA;ICGC;COSMIC	8.561	Up-regulation
CAMK_CAMK2_CAMK2D_ST	Q08289	CACNB2	Q13557	CAMK2D	S73	S67N	67	Missense	distal	-6	no	31.106	40.759	EPSD	TCGA;ICGC;COSMIC	37.605	Gain
CAMK_CAMK2_CAMK2D_ST	Q08289	CACNB2	Q13557	CAMK2D	S218	P220H	220	Missense	proximal	2	no	51.476	50.134	EPSD	TCGA;COSMIC	37.605	Down-regulation
CAMK_CAMK2_CAMK2D_ST	Q08289	CACNB2	Q13557	CAMK2D	S218	P220L	220	Missense	proximal	2	no	51.476	55.345	EPSD	TCGA;COSMIC	37.605	Up-regulation
CAMK_CAMK2_CAMK2D_ST	Q08289	CACNB2	Q13557	CAMK2D	S218	R216G	216	Missense	proximal	-2	no	51.476	50.759	EPSD	TCGA;COSMIC	37.605	Down-regulation
CAMK_CAMK2_CAMK2D_ST	Q08289	CACNB2	Q13557	CAMK2D	T219	P220H	220	Missense	proximal	1	no	42.441	46.030	EPSD	TCGA;COSMIC	37.605	Up-regulation
CAMK_CAMK2_CAMK2D_ST	Q08289	CACNB2	Q13557	CAMK2D	T219	P220L	220	Missense	proximal	1	no	42.441	45.980	EPSD	TCGA;COSMIC	37.605	Up-regulation
CAMK_CAMK2_CAMK2D_ST	Q08289	CACNB2	Q13557	CAMK2D	T219	R216G	216	Missense	distal	-3	no	42.441	-0.517	EPSD	TCGA;COSMIC	37.605	Loss
CAMK_CAMK2_CAMK2D_ST	Q08289	CACNB2	Q13557	CAMK2D	T254	H257Y	257	Missense	distal	3	no	25.219	39.868	EPSD	TCGA;COSMIC	37.605	Gain
CAMK_CAMK2_CAMK2D_ST	Q08289	CACNB2	Q13557	CAMK2D	S514	R511C	511	Missense	distal	-3	no	56.286	26.784	EPSD	TCGA;COSMIC	37.605	Loss
CAMK_CAMK2_CAMK2D_ST	Q08289	CACNB2	Q13557	CAMK2D	S534	R531H	531	Missense	distal	-3	no	49.774	12.450	EPSD	TCGA;COSMIC	37.605	Loss
CAMK_CAMK2_CAMK2D_ST	Q08289	CACNB2	Q13557	CAMK2D	S534	K527T	527	Missense	distal	-7	no	49.774	45.326	EPSD	TCGA;COSMIC	37.605	Down-regulation
CAMK_CAMK2_CAMK2D_ST	Q08289	CACNB2	Q13557	CAMK2D	S534	R531C	531	Missense	distal	-3	no	49.774	20.272	EPSD	TCGA;COSMIC	37.605	Loss
CAMK_CAMK2_CAMK2D_ST	Q08289	CACNB2	Q13557	CAMK2D	T545	S550P	550	Missense	distal	5	no	49.445	52.298	EPSD	TCGA;COSMIC	37.605	Up-regulation
CAMK_CAMK2_CAMK2D_ST	Q08289	CACNB2	Q13557	CAMK2D	T545	R547S	547	Missense	proximal	2	no	49.445	50.251	EPSD	TCGA;COSMIC	37.605	Up-regulation
CAMK_CAMK2_CAMK2D_ST	Q08289	CACNB2	Q13557	CAMK2D	T545	R547H	547	Missense	proximal	2	no	49.445	46.489	EPSD	TCGA;COSMIC	37.605	Down-regulation
CAMK_CAMK2_CAMK2D_ST	Q08289	CACNB2	Q13557	CAMK2D	S546	S550P	550	Missense	distal	4	no	52.500	52.728	EPSD	TCGA;COSMIC	37.605	Up-regulation
CAMK_CAMK2_CAMK2D_ST	Q08289	CACNB2	Q13557	CAMK2D	S546	E553K	553	Missense	distal	7	no	52.500	52.579	EPSD	TCGA;COSMIC	37.605	Up-regulation
CAMK_CAMK2_CAMK2D_ST	Q08289	CACNB2	Q13557	CAMK2D	S546	R547S	547	Missense	proximal	1	no	52.500	46.274	EPSD	TCGA;COSMIC	37.605	Down-regulation
CAMK_CAMK2_CAMK2D_ST	Q08289	CACNB2	Q13557	CAMK2D	S546	E553D	553	Missense	distal	7	no	52.500	52.850	EPSD	TCGA	37.605	Up-regulation
CAMK_CAMK2_CAMK2D_ST	Q08289	CACNB2	Q13557	CAMK2D	S546	R547H	547	Missense	proximal	1	no	52.500	46.230	EPSD	TCGA;COSMIC	37.605	Down-regulation
CAMK_CAMK2_CAMK2D_ST	Q08289	CACNB2	Q13557	CAMK2D	S550	S550P	550	Missense	central	0	yes	41.780	0.000	EPSD	TCGA;COSMIC	37.605	Loss
CAMK_CAMK2_CAMK2D_ST	Q08289	CACNB2	Q13557	CAMK2D	S550	E553K	553	Missense	distal	3	no	41.780	35.761	EPSD	TCGA;COSMIC	37.605	Loss
CAMK_CAMK2_CAMK2D_ST	Q08289	CACNB2	Q13557	CAMK2D	S550	R547S	547	Missense	distal	-3	no	41.780	25.606	EPSD	TCGA;COSMIC	37.605	Loss
CAMK_CAMK2_CAMK2D_ST	Q08289	CACNB2	Q13557	CAMK2D	S550	E553D	553	Missense	distal	3	no	41.780	29.195	EPSD	TCGA	37.605	Loss
CAMK_CAMK2_CAMK2D_ST	Q08289	CACNB2	Q13557	CAMK2D	S550	R547H	547	Missense	distal	-3	no	41.780	4.456	EPSD	TCGA;COSMIC	37.605	Loss
CAMK_CAMK2_CAMK2D_ST	Q08289	CACNB2	Q13557	CAMK2D	T554	S550P	550	Missense	distal	-4	no	87.151	87.711	EPSD	TCGA;COSMIC	37.605	Up-regulation
CAMK_CAMK2_CAMK2D_ST	Q08289	CACNB2	Q13557	CAMK2D	T554	E553K	553	Missense	proximal	-1	no	87.151	87.545	EPSD	TCGA;COSMIC	37.605	Up-regulation
CAMK_CAMK2_CAMK2D_ST	Q08289	CACNB2	Q13557	CAMK2D	T554	R547S	547	Missense	distal	-7	no	87.151	85.092	EPSD	TCGA;COSMIC	37.605	Down-regulation
CAMK_CAMK2_CAMK2D_ST	Q08289	CACNB2	Q13557	CAMK2D	T554	E553D	553	Missense	proximal	-1	no	87.151	84.794	EPSD	TCGA	37.605	Down-regulation
CAMK_CAMK2_CAMK2D_ST	Q08289	CACNB2	Q13557	CAMK2D	T554	R547H	547	Missense	distal	-7	no	87.151	81.902	EPSD	TCGA;COSMIC	37.605	Down-regulation
CAMK_CAMK2_CAMK2D_ST	Q08289	CACNB2	Q13557	CAMK2D	S609	R610Q	610	Missense	proximal	1	no	47.359	42.197	EPSD	TCGA;COSMIC	37.605	Down-regulation
CAMK_CAMK2_CAMK2D_ST	Q08289	CACNB2	Q13557	CAMK2D	S609	D613V	613	Missense	distal	4	no	47.359	46.709	EPSD	TCGA;COSMIC	37.605	Down-regulation
CAMK_CAMK2_CAMK2D_ST	Q08289	CACNB2	Q13557	CAMK2D	S609	E615K	615	Missense	distal	6	no	47.359	47.906	EPSD	TCGA;COSMIC	37.605	Up-regulation
CAMK_CAMK2_CAMK2D_ST	Q08289	CACNB2	Q13557	CAMK2D	S609	R606Q	606	Missense	distal	-3	no	47.359	36.136	EPSD	TCGA	37.605	Loss
CAMK_CAMK2_CAMK2D_ST	P51787	KCNQ1	Q13557	CAMK2D	T404	L405V	405	Missense	proximal	1	no	37.472	39.641	EPSD	TCGA;ICGC;COSMIC	37.605	Gain
CAMK_CAMK2_CAMK2D_ST	P51787	KCNQ1	Q13557	CAMK2D	T470	V465L	465	Missense	distal	-5	no	43.465	41.984	EPSD	TCGA;ICGC;COSMIC	37.605	Down-regulation
CAMK_CAMK2_CAMK2D_ST	P51787	KCNQ1	Q13557	CAMK2D	S484	S484N	484	Missense	central	0	yes	44.012	0.000	PhosphoSitePlus;EPSD	TCGA;ICGC;COSMIC	37.605	Loss
CAMK_CAMK2_CAMK2D_ST	P56524	HDAC4	Q13557	CAMK2D	S210	G204R	204	Missense	distal	-6	no	71.895	73.712	PhosphoSitePlus	TCGA;COSMIC	37.605	Up-regulation
CAMK_CAMK2_CAMK2D_ST	P56524	HDAC4	Q13557	CAMK2D	S246	L241F	241	Missense	distal	-5	no	37.379	39.312	EPSD	TCGA;COSMIC	37.605	Gain
CAMK_CAMK2_CAMK2D_ST	P56524	HDAC4	Q13557	CAMK2D	S246	R253W	253	Missense	distal	7	no	37.379	39.903	EPSD	TCGA;COSMIC	37.605	Gain
CAMK_CAMK2_CAMK2D_ST	P56524	HDAC4	Q13557	CAMK2D	S246	P248L	248	Missense	proximal	2	no	37.379	41.248	EPSD	TCGA;COSMIC	37.605	Gain
CAMK_CAMK2_CAMK2D_ST	P56524	HDAC4	Q13557	CAMK2D	S302	G299R	299	Missense	distal	-3	no	-3.683	39.275	EPSD	TCGA;COSMIC	37.605	Gain
CAMK_CAMK2_CAMK2D_ST	P56524	HDAC4	Q13557	CAMK2D	S309	V310I	310	Missense	proximal	1	no	34.159	39.882	EPSD	TCGA;COSMIC	37.605	Gain
CAMK_CAMK2_CAMK2D_ST	P56524	HDAC4	Q13557	CAMK2D	T465	R460H	460	Missense	distal	-5	no	38.887	40.792	EPSD	TCGA;COSMIC	37.605	Up-regulation
CAMK_CAMK2_CAMK2D_ST	P56524	HDAC4	Q13557	CAMK2D	T465	R464W	464	Missense	proximal	-1	no	38.887	34.822	EPSD	TCGA;COSMIC	37.605	Loss
CAMK_CAMK2_CAMK2D_ST	P56524	HDAC4	Q13557	CAMK2D	S584	E587Q	587	Missense	distal	3	no	42.806	37.207	EPSD	TCGA	37.605	Loss
CAMK_CAMK2_CAMK2D_ST	P56524	HDAC4	Q13557	CAMK2D	S584	R581C	581	Missense	distal	-3	no	42.806	13.304	EPSD	TCGA;COSMIC	37.605	Loss
CAMK_CAMK2_CAMK2D_ST	P56524	HDAC4	Q13557	CAMK2D	S584	P578L	578	Missense	distal	-6	no	42.806	35.856	EPSD	TCGA;COSMIC	37.605	Loss
CAMK_CAMK2_CAMK2D_ST	P56524	HDAC4	Q13557	CAMK2D	S620	G623D	623	Missense	distal	3	no	38.429	33.758	EPSD	TCGA;COSMIC	37.605	Loss
CAMK_CAMK2_CAMK2D_ST	P56524	HDAC4	Q13557	CAMK2D	S628	G623D	623	Missense	distal	-5	no	51.960	51.833	EPSD	TCGA;COSMIC	37.605	Down-regulation
CAMK_CAMK2_CAMK2D_ST	P56524	HDAC4	Q13557	CAMK2D	S628	A630V	630	Missense	proximal	2	no	51.960	46.085	EPSD	TCGA;COSMIC	37.605	Down-regulation
CAMK_CAMK2_CAMK2D_ST	P56524	HDAC4	Q13557	CAMK2D	S632	A630V	630	Missense	proximal	-2	no	41.998	42.272	EPSD	TCGA;COSMIC	37.605	Up-regulation
CAMK_CAMK2_CAMK2D_ST	P56524	HDAC4	Q13557	CAMK2D	S684	R681K	681	Missense	distal	-3	no	51.709	40.301	EPSD	TCGA;COSMIC	37.605	Down-regulation
CAMK_CAMK2_CAMK2D_ST	P56524	HDAC4	Q13557	CAMK2D	S684	S684G	684	Missense	central	0	yes	51.709	0.000	EPSD	TCGA	37.605	Loss
CAMK_CAMK2_CAMK2D_ST	P56524	HDAC4	Q13557	CAMK2D	S684	A679T	679	Missense	distal	-5	no	51.709	50.624	EPSD	TCGA;COSMIC	37.605	Down-regulation
CAMK_CAMK2_CAMK2D_ST	P13688	CEACAM1	Q13557	CAMK2D	T457	A460T	460	Missense	distal	3	no	49.983	36.856	EPSD;PhosphoSitePlus	TCGA;COSMIC	37.605	Loss
CAMK_CAMK2_CAMK2D_ST	P13688	CEACAM1	Q13557	CAMK2D	T457	D462V	462	Missense	distal	5	no	49.983	53.524	EPSD;PhosphoSitePlus	TCGA	37.605	Up-regulation
CAMK_CAMK2_CAMK2D_ST	P13688	CEACAM1	Q13557	CAMK2D	T457	F454S	454	Missense	distal	-3	no	49.983	48.796	EPSD;PhosphoSitePlus	TCGA	37.605	Down-regulation
CAMK_CAMK2_CAMK2D_ST	P13688	CEACAM1	Q13557	CAMK2D	T457	G455R	455	Missense	proximal	-2	no	49.983	50.700	EPSD;PhosphoSitePlus	TCGA;COSMIC;GDSC;CCLE	37.605	Up-regulation
CAMK_CAMK2_CAMK2D_ST	Q8WZ42	TTN	Q13557	CAMK2D	T114	R109Q	109	Missense	distal	-5	no	48.847	48.631	EPSD	TCGA;ICGC;COSMIC	37.605	Down-regulation
CAMK_CAMK2_CAMK2D_ST	Q8WZ42	TTN	Q13557	CAMK2D	T114	S119I	119	Missense	distal	5	no	48.847	49.558	EPSD	TCGA;ICGC;COSMIC	37.605	Up-regulation
CAMK_CAMK2_CAMK2D_ST	Q8WZ42	TTN	Q13557	CAMK2D	T206	V199L	199	Missense	distal	-7	no	34.995	40.987	EPSD	TCGA;ICGC;COSMIC	37.605	Gain
CAMK_CAMK2_CAMK2D_ST	Q8WZ42	TTN	Q13557	CAMK2D	T219	R220Q	220	Missense	proximal	1	no	47.347	42.184	EPSD	TCGA;ICGC;COSMIC	37.605	Down-regulation
CAMK_CAMK2_CAMK2D_ST	Q8WZ42	TTN	Q13557	CAMK2D	T219	R220P	220	Missense	proximal	1	no	47.347	37.487	EPSD	TCGA;ICGC;COSMIC	37.605	Loss
CAMK_CAMK2_CAMK2D_ST	Q8WZ42	TTN	Q13557	CAMK2D	T219	Q212H	212	Missense	distal	-7	no	47.347	45.345	EPSD	TCGA;ICGC;COSMIC	37.605	Down-regulation
CAMK_CAMK2_CAMK2D_ST	Q8WZ42	TTN	Q13557	CAMK2D	S263	P258L	258	Missense	distal	-5	no	44.737	43.377	EPSD	TCGA;ICGC;COSMIC	37.605	Down-regulation
CAMK_CAMK2_CAMK2D_ST	Q8WZ42	TTN	Q13557	CAMK2D	S263	S263L	263	Missense	central	0	yes	44.737	0.000	EPSD	TCGA;ICGC;COSMIC	37.605	Loss
CAMK_CAMK2_CAMK2D_ST	Q8WZ42	TTN	Q13557	CAMK2D	S263	S265F	265	Missense	proximal	2	no	44.737	38.541	EPSD	TCGA;ICGC;COSMIC	37.605	Down-regulation
CAMK_CAMK2_CAMK2D_ST	Q8WZ42	TTN	Q13557	CAMK2D	S263	P269L	269	Missense	distal	6	no	44.737	38.394	EPSD	TCGA;ICGC;COSMIC	37.605	Down-regulation
CAMK_CAMK2_CAMK2D_ST	Q8WZ42	TTN	Q13557	CAMK2D	S263	K260Q	260	Missense	distal	-3	no	44.737	44.922	EPSD	TCGA;ICGC	37.605	Up-regulation
CAMK_CAMK2_CAMK2D_ST	Q8WZ42	TTN	Q13557	CAMK2D	T267	S263L	263	Missense	distal	-4	no	42.936	41.933	EPSD	TCGA;ICGC;COSMIC	37.605	Down-regulation
CAMK_CAMK2_CAMK2D_ST	Q8WZ42	TTN	Q13557	CAMK2D	T267	S265F	265	Missense	proximal	-2	no	42.936	42.693	EPSD	TCGA;ICGC;COSMIC	37.605	Down-regulation
CAMK_CAMK2_CAMK2D_ST	Q8WZ42	TTN	Q13557	CAMK2D	T267	P269L	269	Missense	proximal	2	no	42.936	46.805	EPSD	TCGA;ICGC;COSMIC	37.605	Up-regulation
CAMK_CAMK2_CAMK2D_ST	Q8WZ42	TTN	Q13557	CAMK2D	T267	K260Q	260	Missense	distal	-7	no	42.936	38.099	EPSD	TCGA;ICGC	37.605	Down-regulation
CAMK_CAMK2_CAMK2D_ST	Q8WZ42	TTN	Q13557	CAMK2D	S270	A275S	275	Missense	distal	5	no	46.240	44.071	EPSD	TCGA;ICGC;COSMIC	37.605	Down-regulation
CAMK_CAMK2_CAMK2D_ST	Q8WZ42	TTN	Q13557	CAMK2D	S270	S263L	263	Missense	distal	-7	no	46.240	49.580	EPSD	TCGA;ICGC;COSMIC	37.605	Up-regulation
CAMK_CAMK2_CAMK2D_ST	Q8WZ42	TTN	Q13557	CAMK2D	S270	S265F	265	Missense	distal	-5	no	46.240	47.435	EPSD	TCGA;ICGC;COSMIC	37.605	Up-regulation
CAMK_CAMK2_CAMK2D_ST	Q8WZ42	TTN	Q13557	CAMK2D	S270	P269L	269	Missense	proximal	-1	no	46.240	48.016	EPSD	TCGA;ICGC;COSMIC	37.605	Up-regulation
CAMK_CAMK2_CAMK2D_ST	Q8WZ42	TTN	Q13557	CAMK2D	S284	S291F	291	Missense	distal	7	no	37.197	37.847	EPSD	TCGA;ICGC;COSMIC	37.605	Gain
CAMK_CAMK2_CAMK2D_ST	Q8WZ42	TTN	Q13557	CAMK2D	T300	P301L	301	Missense	proximal	1	no	34.566	38.104	EPSD	TCGA;ICGC;COSMIC	37.605	Gain
CAMK_CAMK2_CAMK2D_ST	Q8WZ42	TTN	Q13557	CAMK2D	S308	P301L	301	Missense	distal	-7	no	36.459	43.050	EPSD	TCGA;ICGC;COSMIC	37.605	Gain
CAMK_CAMK2_CAMK2D_ST	Q8WZ42	TTN	Q13557	CAMK2D	T334	P339S	339	Missense	distal	5	no	52.348	49.495	EPSD	TCGA;ICGC;COSMIC	37.605	Down-regulation
CAMK_CAMK2_CAMK2D_ST	Q8WZ42	TTN	Q13557	CAMK2D	T334	K329N	329	Missense	distal	-5	no	52.348	54.026	EPSD	TCGA;ICGC;COSMIC	37.605	Up-regulation
CAMK_CAMK2_CAMK2D_ST	Q8WZ42	TTN	Q13557	CAMK2D	T334	R328H	328	Missense	distal	-6	no	52.348	50.173	EPSD	TCGA;ICGC;COSMIC	37.605	Down-regulation
CAMK_CAMK2_CAMK2D_ST	Q8WZ42	TTN	Q13557	CAMK2D	S353	E348G	348	Missense	distal	-5	no	51.118	51.705	EPSD	TCGA;ICGC;COSMIC	37.605	Up-regulation
CAMK_CAMK2_CAMK2D_ST	Q8WZ42	TTN	Q13557	CAMK2D	S353	Q347R	347	Missense	distal	-6	no	51.118	48.256	EPSD	TCGA;ICGC;COSMIC	37.605	Down-regulation
CAMK_CAMK2_CAMK2D_ST	Q8WZ42	TTN	Q13557	CAMK2D	S353	S355Y	355	Missense	proximal	2	no	51.118	44.077	EPSD	TCGA;ICGC;COSMIC	37.605	Down-regulation
CAMK_CAMK2_CAMK2D_ST	Q8WZ42	TTN	Q13557	CAMK2D	S353	V351M	351	Missense	proximal	-2	no	51.118	51.503	EPSD	TCGA;ICGC;COSMIC	37.605	Up-regulation
CAMK_CAMK2_CAMK2D_ST	Q8WZ42	TTN	Q13557	CAMK2D	T559	E558G	558	Missense	proximal	-1	no	46.008	45.862	EPSD	TCGA;ICGC;COSMIC	37.605	Down-regulation
CAMK_CAMK2_CAMK2D_ST	Q8WZ42	TTN	Q13557	CAMK2D	T559	E553D	553	Missense	distal	-6	no	46.008	39.828	EPSD	TCGA;ICGC;COSMIC	37.605	Down-regulation
CAMK_CAMK2_CAMK2D_ST	Q8WZ42	TTN	Q13557	CAMK2D	S837	I839T	839	Missense	proximal	2	no	48.246	44.154	EPSD	TCGA;ICGC;COSMIC	37.605	Down-regulation
CAMK_CAMK2_CAMK2D_ST	Q8WZ42	TTN	Q13557	CAMK2D	S837	G836S	836	Missense	proximal	-1	no	48.246	49.049	EPSD	TCGA;ICGC;COSMIC;CCLE	37.605	Up-regulation
CAMK_CAMK2_CAMK2D_ST	Q8WZ42	TTN	Q13557	CAMK2D	S837	G836R	836	Missense	proximal	-1	no	48.246	50.202	EPSD	TCGA;ICGC;COSMIC	37.605	Up-regulation
CAMK_CAMK2_CAMK2D_ST	Q8WZ42	TTN	Q13557	CAMK2D	S837	A835V	835	Missense	proximal	-2	no	48.246	48.520	EPSD	TCGA;ICGC;COSMIC	37.605	Up-regulation
CAMK_CAMK2_CAMK2D_ST	Q8WZ42	TTN	Q13557	CAMK2D	S837	A835T	835	Missense	proximal	-2	no	48.246	47.779	EPSD	TCGA;ICGC;COSMIC	37.605	Down-regulation
CAMK_CAMK2_CAMK2D_ST	Q8WZ42	TTN	Q13557	CAMK2D	S905	V911I	911	Missense	distal	6	no	40.093	38.345	EPSD	TCGA;ICGC;COSMIC;GDSC;CCLE	37.605	Down-regulation
CAMK_CAMK2_CAMK2D_ST	Q8WZ42	TTN	Q13557	CAMK2D	S905	V898M	898	Missense	distal	-7	no	40.093	45.158	EPSD	TCGA;ICGC;COSMIC	37.605	Up-regulation
CAMK_CAMK2_CAMK2D_ST	Q8WZ42	TTN	Q13557	CAMK2D	S905	K900M	900	Missense	distal	-5	no	40.093	41.061	EPSD	TCGA;ICGC;COSMIC	37.605	Up-regulation
CAMK_CAMK2_CAMK2D_ST	Q8WZ42	TTN	Q13557	CAMK2D	T910	V911I	911	Missense	proximal	1	no	34.525	40.247	EPSD	TCGA;ICGC;COSMIC;GDSC;CCLE	37.605	Gain
CAMK_CAMK2_CAMK2D_ST	Q8WZ42	TTN	Q13557	CAMK2D	T1067	Q1073H	1073	Missense	distal	6	no	41.928	39.858	EPSD	TCGA;ICGC;COSMIC	37.605	Down-regulation
CAMK_CAMK2_CAMK2D_ST	Q8WZ42	TTN	Q13557	CAMK2D	S1249	H1246Q	1246	Missense	distal	-3	no	16.632	42.734	EPSD	TCGA;ICGC;COSMIC	37.605	Gain
CAMK_CAMK2_CAMK2D_ST	Q8WZ42	TTN	Q13557	CAMK2D	S1406	P1407S	1407	Missense	proximal	1	no	36.930	40.564	EPSD	TCGA;ICGC;COSMIC	37.605	Gain
CAMK_CAMK2_CAMK2D_ST	Q8WZ42	TTN	Q13557	CAMK2D	S1413	P1407S	1407	Missense	distal	-6	no	37.564	37.915	EPSD	TCGA;ICGC;COSMIC	37.605	Gain
CAMK_CAMK2_CAMK2D_ST	Q8WZ42	TTN	Q13557	CAMK2D	S1418	R1412G	1412	Missense	distal	-6	no	39.060	37.243	EPSD	TCGA;ICGC;COSMIC	37.605	Loss
CAMK_CAMK2_CAMK2D_ST	Q8WZ42	TTN	Q13557	CAMK2D	S1418	A1425E	1425	Missense	distal	7	no	39.060	39.329	EPSD	TCGA;ICGC;COSMIC	37.605	Up-regulation
CAMK_CAMK2_CAMK2D_ST	Q8WZ42	TTN	Q13557	CAMK2D	S1418	R1416H	1416	Missense	proximal	-2	no	39.060	38.169	EPSD	TCGA;ICGC;COSMIC	37.605	Down-regulation
CAMK_CAMK2_CAMK2D_ST	Q8WZ42	TTN	Q13557	CAMK2D	S1418	P1419S	1419	Missense	proximal	1	no	39.060	42.694	EPSD	TCGA;ICGC;COSMIC	37.605	Up-regulation
CAMK_CAMK2_CAMK2D_ST	Q8WZ42	TTN	Q13557	CAMK2D	S1465	C1468W	1468	Missense	distal	3	no	48.117	33.326	EPSD	TCGA;ICGC;COSMIC	37.605	Loss
CAMK_CAMK2_CAMK2D_ST	Q8WZ42	TTN	Q13557	CAMK2D	S1465	V1464L	1464	Missense	proximal	-1	no	48.117	46.922	EPSD	TCGA;ICGC;COSMIC	37.605	Down-regulation
CAMK_CAMK2_CAMK2D_ST	Q8WZ42	TTN	Q13557	CAMK2D	S1465	V1460L	1460	Missense	distal	-5	no	48.117	46.635	EPSD	TCGA;ICGC;COSMIC	37.605	Down-regulation
CAMK_CAMK2_CAMK2D_ST	Q8WZ42	TTN	Q13557	CAMK2D	S1465	E1470K	1470	Missense	distal	5	no	48.117	48.568	EPSD	TCGA;ICGC;COSMIC	37.605	Up-regulation
CAMK_CAMK2_CAMK2D_ST	Q8WZ42	TTN	Q13557	CAMK2D	S1465	Q1472K	1472	Missense	distal	7	no	48.117	49.343	EPSD	TCGA;ICGC;COSMIC	37.605	Up-regulation
CAMK_CAMK2_CAMK2D_ST	Q8WZ42	TTN	Q13557	CAMK2D	S1465	P1463H	1463	Missense	proximal	-2	no	48.117	47.660	EPSD	TCGA;ICGC	37.605	Down-regulation
CAMK_CAMK2_CAMK2D_ST	Q8WZ42	TTN	Q13557	CAMK2D	T1546	V1543E	1543	Missense	distal	-3	no	38.235	4.928	EPSD	TCGA;ICGC;COSMIC	37.605	Loss
CAMK_CAMK2_CAMK2D_ST	Q8WZ42	TTN	Q13557	CAMK2D	T1546	V1550L	1550	Missense	distal	4	no	38.235	41.339	EPSD	TCGA;ICGC;COSMIC	37.605	Up-regulation
CAMK_CAMK2_CAMK2D_ST	Q8WZ42	TTN	Q13557	CAMK2D	T1546	T1546I	1546	Missense	central	0	yes	38.235	0.000	EPSD	TCGA;ICGC;COSMIC	37.605	Loss
CAMK_CAMK2_CAMK2D_ST	Q8WZ42	TTN	Q13557	CAMK2D	T1546	S1542L	1542	Missense	distal	-4	no	38.235	37.232	EPSD	TCGA;ICGC;COSMIC	37.605	Loss
CAMK_CAMK2_CAMK2D_ST	Q8WZ42	TTN	Q13557	CAMK2D	T1546	I1544T	1544	Missense	proximal	-2	no	38.235	37.256	EPSD	TCGA;ICGC;COSMIC	37.605	Loss
CAMK_CAMK2_CAMK2D_ST	Q8WZ42	TTN	Q13557	CAMK2D	T1546	V1547M	1547	Missense	proximal	1	no	38.235	43.109	EPSD	TCGA;ICGC;COSMIC	37.605	Up-regulation
CAMK_CAMK2_CAMK2D_ST	Q8WZ42	TTN	Q13557	CAMK2D	T1546	V1543A	1543	Missense	distal	-3	no	38.235	24.662	EPSD	TCGA;ICGC	37.605	Loss
CAMK_CAMK2_CAMK2D_ST	Q8WZ42	TTN	Q13557	CAMK2D	T1609	G1611E	1611	Missense	proximal	2	no	50.647	48.952	EPSD	TCGA;ICGC;COSMIC	37.605	Down-regulation
CAMK_CAMK2_CAMK2D_ST	Q8WZ42	TTN	Q13557	CAMK2D	T1609	G1608E	1608	Missense	proximal	-1	no	50.647	50.793	EPSD	TCGA;ICGC;COSMIC	37.605	Up-regulation
CAMK_CAMK2_CAMK2D_ST	Q8WZ42	TTN	Q13557	CAMK2D	T1609	P1602S	1602	Missense	distal	-7	no	50.647	53.899	EPSD	TCGA;ICGC;COSMIC	37.605	Up-regulation
CAMK_CAMK2_CAMK2D_ST	Q8WZ42	TTN	Q13557	CAMK2D	S1622	S1619F	1619	Missense	distal	-3	no	37.251	38.438	EPSD	TCGA;ICGC;COSMIC	37.605	Gain
CAMK_CAMK2_CAMK2D_ST	Q8WZ42	TTN	Q13557	CAMK2D	S2072	A2077V	2077	Missense	distal	5	no	41.747	41.534	EPSD	TCGA;ICGC;COSMIC	37.605	Down-regulation
CAMK_CAMK2_CAMK2D_ST	Q8WZ42	TTN	Q13557	CAMK2D	S2072	P2073S	2073	Missense	proximal	1	no	41.747	45.380	EPSD	TCGA;ICGC;COSMIC	37.605	Up-regulation
CAMK_CAMK2_CAMK2D_ST	Q8WZ42	TTN	Q13557	CAMK2D	S2072	S2072R	2072	Missense	central	0	yes	41.747	0.000	EPSD	TCGA;ICGC;COSMIC	37.605	Loss
CAMK_CAMK2_CAMK2D_ST	Q8WZ42	TTN	Q13557	CAMK2D	S2072	P2078S	2078	Missense	distal	6	no	41.747	35.845	EPSD	TCGA;ICGC;COSMIC	37.605	Loss
CAMK_CAMK2_CAMK2D_ST	Q8WZ42	TTN	Q13557	CAMK2D	S2072	K2079T	2079	Missense	distal	7	no	41.747	42.197	EPSD	TCGA;ICGC	37.605	Up-regulation
CAMK_CAMK2_CAMK2D_ST	Q8WZ42	TTN	Q13557	CAMK2D	T2088	E2082K	2082	Missense	distal	-6	no	40.025	38.042	EPSD	TCGA;ICGC;COSMIC;CCLE	37.605	Down-regulation
CAMK_CAMK2_CAMK2D_ST	Q8WZ42	TTN	Q13557	CAMK2D	T2088	G2092E	2092	Missense	distal	4	no	40.025	40.291	EPSD	TCGA;ICGC;COSMIC	37.605	Up-regulation
CAMK_CAMK2_CAMK2D_ST	Q8WZ42	TTN	Q13557	CAMK2D	T2088	S2093F	2093	Missense	distal	5	no	40.025	38.166	EPSD	TCGA;ICGC;COSMIC	37.605	Down-regulation
CAMK_CAMK2_CAMK2D_ST	Q8WZ42	TTN	Q13557	CAMK2D	T2088	R2083K	2083	Missense	distal	-5	no	40.025	40.051	EPSD	TCGA;ICGC;COSMIC	37.605	Up-regulation
CAMK_CAMK2_CAMK2D_ST	Q8WZ42	TTN	Q13557	CAMK2D	T2088	V2089M	2089	Missense	proximal	1	no	40.025	44.900	EPSD	TCGA;ICGC	37.605	Up-regulation
CAMK_CAMK2_CAMK2D_ST	Q8WZ42	TTN	Q13557	CAMK2D	T2193	A2192V	2192	Missense	proximal	-1	no	44.487	45.745	EPSD	TCGA;ICGC;COSMIC	37.605	Up-regulation
CAMK_CAMK2_CAMK2D_ST	Q8WZ42	TTN	Q13557	CAMK2D	T2193	A2192T	2192	Missense	proximal	-1	no	44.487	46.142	EPSD	TCGA;ICGC	37.605	Up-regulation
CAMK_CAMK2_CAMK2D_ST	Q8WZ42	TTN	Q13557	CAMK2D	T2507	N2505Y	2505	Missense	proximal	-2	no	45.070	44.039	EPSD	TCGA;ICGC;COSMIC	37.605	Down-regulation
CAMK_CAMK2_CAMK2D_ST	Q8WZ42	TTN	Q13557	CAMK2D	T2507	N2505D	2505	Missense	proximal	-2	no	45.070	44.363	EPSD	TCGA;ICGC	37.605	Down-regulation
CAMK_CAMK2_CAMK2D_ST	Q8WZ42	TTN	Q13557	CAMK2D	T2507	R2506Q	2506	Missense	proximal	-1	no	45.070	42.167	EPSD	TCGA;ICGC;COSMIC	37.605	Down-regulation
CAMK_CAMK2_CAMK2D_ST	Q8WZ42	TTN	Q13557	CAMK2D	T2507	A2509S	2509	Missense	proximal	2	no	45.070	43.690	EPSD	TCGA;ICGC;COSMIC	37.605	Down-regulation
CAMK_CAMK2_CAMK2D_ST	Q8WZ42	TTN	Q13557	CAMK2D	S2749	E2751K	2751	Missense	proximal	2	no	45.043	40.726	EPSD	TCGA;ICGC;COSMIC	37.605	Down-regulation
CAMK_CAMK2_CAMK2D_ST	Q8WZ42	TTN	Q13557	CAMK2D	S2749	G2744E	2744	Missense	distal	-5	no	45.043	44.456	EPSD	TCGA;ICGC;COSMIC	37.605	Down-regulation
CAMK_CAMK2_CAMK2D_ST	Q8WZ42	TTN	Q13557	CAMK2D	S2749	K2752R	2752	Missense	distal	3	no	45.043	46.359	EPSD	TCGA;ICGC;COSMIC	37.605	Up-regulation
CAMK_CAMK2_CAMK2D_ST	Q8WZ42	TTN	Q13557	CAMK2D	S2749	S2756C	2756	Missense	distal	7	no	45.043	47.021	EPSD	TCGA	37.605	Up-regulation
CAMK_CAMK2_CAMK2D_ST	Q8WZ42	TTN	Q13557	CAMK2D	T3119	G3125R	3125	Missense	distal	6	no	55.190	54.719	EPSD	TCGA;ICGC;COSMIC	37.605	Down-regulation
CAMK_CAMK2_CAMK2D_ST	Q8WZ42	TTN	Q13557	CAMK2D	T3119	M3121I	3121	Missense	proximal	2	no	55.190	58.933	EPSD	TCGA;ICGC;COSMIC	37.605	Up-regulation
CAMK_CAMK2_CAMK2D_ST	Q8WZ42	TTN	Q13557	CAMK2D	T3119	K3126E	3126	Missense	distal	7	no	55.190	55.112	EPSD	TCGA;ICGC;COSMIC	37.605	Down-regulation
CAMK_CAMK2_CAMK2D_ST	Q8WZ42	TTN	Q13557	CAMK2D	T3119	K3126T	3126	Missense	distal	7	no	55.190	55.640	EPSD	TCGA;ICGC;COSMIC	37.605	Up-regulation
CAMK_CAMK2_CAMK2D_ST	Q8WZ42	TTN	Q13557	CAMK2D	T3128	G3125R	3125	Missense	distal	-3	no	16.900	59.858	EPSD	TCGA;ICGC;COSMIC	37.605	Gain
CAMK_CAMK2_CAMK2D_ST	Q8WZ42	TTN	Q13557	CAMK2D	S3208	R3204Q	3204	Missense	distal	-4	no	41.212	38.215	EPSD	TCGA;ICGC	37.605	Down-regulation
CAMK_CAMK2_CAMK2D_ST	Q8WZ42	TTN	Q13557	CAMK2D	T3249	L3242V	3242	Missense	distal	-7	no	49.492	43.500	EPSD	TCGA;ICGC;COSMIC	37.605	Down-regulation
CAMK_CAMK2_CAMK2D_ST	Q8WZ42	TTN	Q13557	CAMK2D	S3379	D3381N	3381	Missense	proximal	2	no	41.287	29.862	EPSD	TCGA;ICGC	37.605	Loss
CAMK_CAMK2_CAMK2D_ST	Q8WZ42	TTN	Q13557	CAMK2D	S3379	D3381E	3381	Missense	proximal	2	no	41.287	33.861	EPSD	TCGA;ICGC;COSMIC	37.605	Loss
CAMK_CAMK2_CAMK2D_ST	Q8WZ42	TTN	Q13557	CAMK2D	S3379	D3381H	3381	Missense	proximal	2	no	41.287	29.713	EPSD	TCGA;ICGC;COSMIC	37.605	Loss
CAMK_CAMK2_CAMK2D_ST	Q8WZ42	TTN	Q13557	CAMK2D	S3379	I3384S	3384	Missense	distal	5	no	41.287	40.576	EPSD	TCGA;ICGC;COSMIC	37.605	Down-regulation
CAMK_CAMK2_CAMK2D_ST	Q8WZ42	TTN	Q13557	CAMK2D	S3379	K3383N	3383	Missense	distal	4	no	41.287	40.871	EPSD	TCGA;ICGC	37.605	Down-regulation
CAMK_CAMK2_CAMK2D_ST	Q8WZ42	TTN	Q13557	CAMK2D	S3379	S3376L	3376	Missense	distal	-3	no	41.287	35.625	EPSD	TCGA;ICGC;COSMIC	37.605	Loss
CAMK_CAMK2_CAMK2D_ST	Q8WZ42	TTN	Q13557	CAMK2D	T3934	E3930K	3930	Missense	distal	-4	no	53.679	56.933	EPSD	TCGA;COSMIC	37.605	Up-regulation
CAMK_CAMK2_CAMK2D_ST	Q8WZ42	TTN	Q13557	CAMK2D	S4486	T4489K	4489	Missense	distal	3	no	41.087	44.779	EPSD	TCGA;COSMIC	37.605	Up-regulation
CAMK_CAMK2_CAMK2D_ST	Q8WZ42	TTN	Q13557	CAMK2D	T5358	R5364H	5364	Missense	distal	6	no	53.250	53.732	EPSD	TCGA;COSMIC	37.605	Up-regulation
CAMK_CAMK2_CAMK2D_ST	Q8WZ42	TTN	Q13557	CAMK2D	T5358	R5364C	5364	Missense	distal	6	no	53.250	52.574	EPSD	TCGA;COSMIC	37.605	Down-regulation
CAMK_CAMK2_CAMK2D_ST	Q8WZ42	TTN	Q13557	CAMK2D	S5401	S5400Y	5400	Missense	proximal	-1	no	40.655	39.156	EPSD	TCGA	37.605	Down-regulation
CAMK_CAMK2_CAMK2D_ST	Q8WZ42	TTN	Q13557	CAMK2D	S7308	E7307K	7307	Missense	proximal	-1	no	40.027	40.421	EPSD	TCGA;ICGC;COSMIC	37.605	Up-regulation
CAMK_CAMK2_CAMK2D_ST	Q8WZ42	TTN	Q13557	CAMK2D	S8740	L8742F	8742	Missense	proximal	2	no	40.516	32.872	EPSD	TCGA;COSMIC	37.605	Loss
CAMK_CAMK2_CAMK2D_ST	Q8WZ42	TTN	Q13557	CAMK2D	S9633	S9633L	9633	Missense	central	0	yes	39.074	0.000	EPSD	TCGA;COSMIC	37.605	Loss
CAMK_CAMK2_CAMK2D_ST	Q8WZ42	TTN	Q13557	CAMK2D	T14633	K14634N	14634	Missense	proximal	1	no	39.528	38.806	EPSD	TCGA;ICGC;COSMIC;CCLE	37.605	Down-regulation
CAMK_CAMK2_CAMK2D_ST	Q8WZ42	TTN	Q13557	CAMK2D	S14680	S14683R	14683	Missense	distal	3	no	48.343	46.687	EPSD	TCGA;COSMIC	37.605	Down-regulation
CAMK_CAMK2_CAMK2D_ST	Q8WZ42	TTN	Q13557	CAMK2D	S14680	S14683T	14683	Missense	distal	3	no	48.343	41.678	EPSD	TCGA;COSMIC	37.605	Down-regulation
CAMK_CAMK2_CAMK2D_ST	Q8WZ42	TTN	Q13557	CAMK2D	T17410	T17405A	17405	Missense	distal	-5	no	44.647	45.731	EPSD	TCGA;COSMIC	37.605	Up-regulation
CAMK_CAMK2_CAMK2D_ST	Q8WZ42	TTN	Q13557	CAMK2D	T17591	P17592H	17592	Missense	proximal	1	no	34.283	37.872	EPSD	TCGA;COSMIC	37.605	Gain
CAMK_CAMK2_CAMK2D_ST	Q8WZ42	TTN	Q13557	CAMK2D	T17596	W17590S	17590	Missense	distal	-6	no	33.027	38.276	EPSD	TCGA;COSMIC	37.605	Gain
CAMK_CAMK2_CAMK2D_ST	Q8WZ42	TTN	Q13557	CAMK2D	S17929	D17928E	17928	Missense	proximal	-1	no	42.182	44.539	EPSD	TCGA;COSMIC	37.605	Up-regulation
CAMK_CAMK2_CAMK2D_ST	Q8WZ42	TTN	Q13557	CAMK2D	S19893	S19893L	19893	Missense	central	0	yes	45.314	0.000	EPSD	TCGA;COSMIC	37.605	Loss
CAMK_CAMK2_CAMK2D_ST	Q8WZ42	TTN	Q13557	CAMK2D	S20205	S20202R	20202	Missense	distal	-3	no	37.917	54.091	EPSD	TCGA;COSMIC	37.605	Up-regulation
CAMK_CAMK2_CAMK2D_ST	Q8WZ42	TTN	Q13557	CAMK2D	T20477	I20470T	20470	Missense	distal	-7	no	49.398	45.831	EPSD	TCGA;COSMIC	37.605	Down-regulation
CAMK_CAMK2_CAMK2D_ST	Q8WZ42	TTN	Q13557	CAMK2D	T22152	K22146N	22146	Missense	distal	-6	no	55.095	64.061	EPSD	TCGA;COSMIC;CCLE	37.605	Up-regulation
CAMK_CAMK2_CAMK2D_ST	Q8WZ42	TTN	Q13557	CAMK2D	S22496	E22493K	22493	Missense	distal	-3	no	9.771	44.054	EPSD	TCGA;ICGC;COSMIC	37.605	Gain
CAMK_CAMK2_CAMK2D_ST	Q8WZ42	TTN	Q13557	CAMK2D	S25507	E25503A	25503	Missense	distal	-4	no	36.196	40.037	EPSD	TCGA;COSMIC	37.605	Gain
CAMK_CAMK2_CAMK2D_ST	Q8WZ42	TTN	Q13557	CAMK2D	T26480	F26486L	26486	Missense	distal	6	no	51.713	52.074	EPSD	TCGA;COSMIC	37.605	Up-regulation
CAMK_CAMK2_CAMK2D_ST	Q8WZ42	TTN	Q13557	CAMK2D	T26972	V26969I	26969	Missense	distal	-3	no	54.033	53.314	EPSD	TCGA	37.605	Down-regulation
CAMK_CAMK2_CAMK2D_ST	Q8WZ42	TTN	Q13557	CAMK2D	T28145	S28144L	28144	Missense	proximal	-1	no	41.140	39.707	EPSD	TCGA;COSMIC	37.605	Down-regulation
CAMK_CAMK2_CAMK2D_ST	Q8WZ42	TTN	Q13557	CAMK2D	S28636	S28637T	28637	Missense	proximal	1	no	44.404	42.002	EPSD	TCGA;COSMIC	37.605	Down-regulation
CAMK_CAMK2_CAMK2D_ST	Q8WZ42	TTN	Q13557	CAMK2D	S29421	S29418F	29418	Missense	distal	-3	no	41.183	42.370	EPSD	TCGA;COSMIC	37.605	Up-regulation
CAMK_CAMK2_CAMK2D_ST	Q8WZ42	TTN	Q13557	CAMK2D	T29626	S29622Y	29622	Missense	distal	-4	no	54.274	56.829	EPSD	TCGA	37.605	Up-regulation
CAMK_CAMK2_CAMK2D_ST	Q8WZ42	TTN	Q13557	CAMK2D	S29720	Q29716R	29716	Missense	distal	-4	no	45.048	48.044	EPSD	TCGA;COSMIC	37.605	Up-regulation
CAMK_CAMK2_CAMK2D_ST	Q8WZ42	TTN	Q13557	CAMK2D	S30920	T30921R	30921	Missense	proximal	1	no	35.937	44.565	EPSD	TCGA;COSMIC	37.605	Gain
CAMK_CAMK2_CAMK2D_ST	Q8WZ42	TTN	Q13557	CAMK2D	T31204	A31200V	31200	Missense	distal	-4	no	47.250	48.701	EPSD	TCGA;COSMIC	37.605	Up-regulation
CAMK_CAMK2_CAMK2D_ST	Q8WZ42	TTN	Q13557	CAMK2D	T33169	I33174M	33174	Missense	distal	5	no	45.214	43.121	EPSD	TCGA;COSMIC	37.605	Down-regulation
CAMK_CAMK2_CAMK2D_ST	Q8WZ42	TTN	Q13557	CAMK2D	S33203	L33202P	33202	Missense	proximal	-1	no	48.714	46.938	EPSD	TCGA	37.605	Down-regulation
CAMK_CAMK2_CAMK2D_ST	Q8WZ42	TTN	Q13557	CAMK2D	T33626	P33625H	33625	Missense	proximal	-1	no	49.680	49.563	EPSD	TCGA;COSMIC	37.605	Down-regulation
CAMK_CAMK2_CAMK2D_ST	Q8WZ42	TTN	Q13557	CAMK2D	S34108	S34112T	34112	Missense	distal	4	no	43.454	42.576	EPSD	TCGA	37.605	Down-regulation
CAMK_CAMK2_CAMK2D_ST	Q8WZ42	TTN	Q13557	CAMK2D	S34266	E34259Q	34259	Missense	distal	-7	no	52.585	54.016	EPSD	TCGA	37.605	Up-regulation
CAMK_CAMK2_CAMK2D_ST	Q14524	SCN5A	Q13557	CAMK2D	T17	R15S	15	Missense	proximal	-2	no	50.514	49.981	EPSD	TCGA;ICGC;COSMIC	37.605	Down-regulation
CAMK_CAMK2_CAMK2D_ST	Q14524	SCN5A	Q13557	CAMK2D	T17	E19Q	19	Missense	proximal	2	no	50.514	50.075	EPSD	TCGA;ICGC;COSMIC	37.605	Down-regulation
CAMK_CAMK2_CAMK2D_ST	Q14524	SCN5A	Q13557	CAMK2D	T17	R14C	14	Missense	distal	-3	no	50.514	21.011	EPSD	TCGA;ICGC;GDSC;CCLE	37.605	Loss
CAMK_CAMK2_CAMK2D_ST	Q14524	SCN5A	Q13557	CAMK2D	T37	R43Q	43	Missense	distal	6	no	45.792	48.342	EPSD	TCGA;ICGC;COSMIC	37.605	Up-regulation
CAMK_CAMK2_CAMK2D_ST	Q14524	SCN5A	Q13557	CAMK2D	T37	S36L	36	Missense	proximal	-1	no	45.792	44.358	EPSD	TCGA;ICGC;COSMIC	37.605	Down-regulation
CAMK_CAMK2_CAMK2D_ST	Q14524	SCN5A	Q13557	CAMK2D	T37	E41K	41	Missense	distal	4	no	45.792	46.247	EPSD	TCGA;ICGC;COSMIC	37.605	Up-regulation
CAMK_CAMK2_CAMK2D_ST	Q14524	SCN5A	Q13557	CAMK2D	T37	R34H	34	Missense	distal	-3	no	45.792	8.467	EPSD	TCGA;ICGC;COSMIC	37.605	Loss
CAMK_CAMK2_CAMK2D_ST	Q14524	SCN5A	Q13557	CAMK2D	S231	T229N	229	Missense	proximal	-2	no	40.944	42.027	EPSD	TCGA;ICGC;COSMIC	37.605	Up-regulation
CAMK_CAMK2_CAMK2D_ST	Q14524	SCN5A	Q13557	CAMK2D	S483	K477N	477	Missense	distal	-6	no	31.227	40.193	EPSD	TCGA;ICGC;COSMIC	37.605	Gain
CAMK_CAMK2_CAMK2D_ST	Q14524	SCN5A	Q13557	CAMK2D	S484	K477N	477	Missense	distal	-7	no	45.288	38.502	EPSD	TCGA;ICGC;COSMIC	37.605	Down-regulation
CAMK_CAMK2_CAMK2D_ST	Q14524	SCN5A	Q13557	CAMK2D	S484	R478M	478	Missense	distal	-6	no	45.288	40.479	EPSD	TCGA;ICGC;COSMIC	37.605	Down-regulation
CAMK_CAMK2_CAMK2D_ST	Q14524	SCN5A	Q13557	CAMK2D	S484	E488G	488	Missense	distal	4	no	45.288	45.022	EPSD	TCGA;ICGC;COSMIC	37.605	Down-regulation
CAMK_CAMK2_CAMK2D_ST	Q14524	SCN5A	Q13557	CAMK2D	S484	G485E	485	Missense	proximal	1	no	45.288	44.291	EPSD	TCGA;ICGC;COSMIC	37.605	Down-regulation
CAMK_CAMK2_CAMK2D_ST	Q14524	SCN5A	Q13557	CAMK2D	S484	S484L	484	Missense	central	0	yes	45.288	0.000	EPSD	TCGA;ICGC;COSMIC	37.605	Loss
CAMK_CAMK2_CAMK2D_ST	Q14524	SCN5A	Q13557	CAMK2D	S497	D501N	501	Missense	distal	4	no	36.751	38.375	EPSD	TCGA;ICGC	37.605	Gain
CAMK_CAMK2_CAMK2D_ST	Q14524	SCN5A	Q13557	CAMK2D	S516	R523H	523	Missense	distal	7	no	71.045	72.117	PhosphoSitePlus;EPSD	TCGA;ICGC;COSMIC	37.605	Up-regulation
CAMK_CAMK2_CAMK2D_ST	Q14524	SCN5A	Q13557	CAMK2D	S516	R513H	513	Missense	distal	-3	no	71.045	33.720	PhosphoSitePlus;EPSD	TCGA;ICGC;COSMIC	37.605	Loss
CAMK_CAMK2_CAMK2D_ST	Q14524	SCN5A	Q13557	CAMK2D	T580	A582D	582	Missense	proximal	2	no	36.592	43.023	EPSD	TCGA;ICGC;COSMIC	37.605	Gain
CAMK_CAMK2_CAMK2D_ST	Q14524	SCN5A	Q13557	CAMK2D	T580	G574E	574	Missense	distal	-6	no	36.592	37.982	EPSD	TCGA;ICGC;COSMIC	37.605	Gain
CAMK_CAMK2_CAMK2D_ST	Q14524	SCN5A	Q13557	CAMK2D	T594	V595G	595	Missense	proximal	1	no	79.320	78.717	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	37.605	Down-regulation
CAMK_CAMK2_CAMK2D_ST	Q14524	SCN5A	Q13557	CAMK2D	T594	C597S	597	Missense	distal	3	no	79.320	78.284	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	37.605	Down-regulation
CAMK_CAMK2_CAMK2D_ST	Q14524	SCN5A	Q13557	CAMK2D	T594	S593N	593	Missense	proximal	-1	no	79.320	78.292	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC;GDSC	37.605	Down-regulation
CAMK_CAMK2_CAMK2D_ST	Q14524	SCN5A	Q13557	CAMK2D	S667	R661Q	661	Missense	distal	-6	no	36.570	39.432	EPSD	TCGA;ICGC;COSMIC	37.605	Gain
CAMK_CAMK2_CAMK2D_ST	Q14524	SCN5A	Q13557	CAMK2D	S671	E678K	678	Missense	distal	7	no	45.789	45.868	EPSD	TCGA;ICGC;COSMIC	37.605	Up-regulation
CAMK_CAMK2_CAMK2D_ST	Q14524	SCN5A	Q13557	CAMK2D	S805	R808C	808	Missense	distal	3	no	38.187	40.879	EPSD	TCGA;ICGC;COSMIC;GDSC;CCLE	37.605	Up-regulation
CAMK_CAMK2_CAMK2D_ST	Q14524	SCN5A	Q13557	CAMK2D	S805	R808H	808	Missense	distal	3	no	38.187	28.640	EPSD	TCGA;ICGC;COSMIC	37.605	Loss
CAMK_CAMK2_CAMK2D_ST	Q14524	SCN5A	Q13557	CAMK2D	S805	S805L	805	Missense	central	0	yes	38.187	0.000	EPSD	TCGA;ICGC;COSMIC	37.605	Loss
CAMK_CAMK2_CAMK2D_ST	Q14524	SCN5A	Q13557	CAMK2D	S805	R811S	811	Missense	distal	6	no	38.187	37.147	EPSD	TCGA;ICGC;COSMIC	37.605	Loss
CAMK_CAMK2_CAMK2D_ST	Q14524	SCN5A	Q13557	CAMK2D	S805	L807M	807	Missense	proximal	2	no	38.187	33.817	EPSD	TCGA;ICGC	37.605	Loss
CAMK_CAMK2_CAMK2D_ST	Q14524	SCN5A	Q13557	CAMK2D	S1003	A997S	997	Missense	distal	-6	no	42.601	41.312	EPSD	TCGA;ICGC;COSMIC	37.605	Down-regulation
CAMK_CAMK2_CAMK2D_ST	Q14524	SCN5A	Q13557	CAMK2D	S1003	Q998H	998	Missense	distal	-5	no	42.601	44.721	EPSD	TCGA;ICGC;COSMIC	37.605	Up-regulation
CAMK_CAMK2_CAMK2D_ST	Q14524	SCN5A	Q13557	CAMK2D	S1003	P1008S	1008	Missense	distal	5	no	42.601	39.748	EPSD	TCGA;ICGC;COSMIC	37.605	Down-regulation
CAMK_CAMK2_CAMK2D_ST	Q14524	SCN5A	Q13557	CAMK2D	S1003	P1008L	1008	Missense	distal	5	no	42.601	38.857	EPSD	TCGA;ICGC;COSMIC	37.605	Down-regulation
CAMK_CAMK2_CAMK2D_ST	Q14524	SCN5A	Q13557	CAMK2D	S1083	Q1077R	1077	Missense	distal	-6	no	51.699	48.837	EPSD	TCGA;COSMIC	37.605	Down-regulation
CAMK_CAMK2_CAMK2D_ST	Q14524	SCN5A	Q13557	CAMK2D	S1083	V1082G	1082	Missense	proximal	-1	no	51.699	51.135	EPSD	TCGA;COSMIC	37.605	Down-regulation
CAMK_CAMK2_CAMK2D_ST	Q14524	SCN5A	Q13557	CAMK2D	S1083	G1084C	1084	Missense	proximal	1	no	51.699	45.651	EPSD	TCGA;COSMIC	37.605	Down-regulation
CAMK_CAMK2_CAMK2D_ST	Q14524	SCN5A	Q13557	CAMK2D	S1083	P1081L	1081	Missense	proximal	-2	no	51.699	51.226	EPSD	TCGA;COSMIC	37.605	Down-regulation
CAMK_CAMK2_CAMK2D_ST	Q14524	SCN5A	Q13557	CAMK2D	S1083	E1078K	1078	Missense	distal	-5	no	51.699	50.523	EPSD	TCGA;COSMIC	37.605	Down-regulation
CAMK_CAMK2_CAMK2D_ST	Q14524	SCN5A	Q13557	CAMK2D	S1083	S1079F	1079	Missense	distal	-4	no	51.699	49.443	EPSD	TCGA;COSMIC	37.605	Down-regulation
CAMK_CAMK2_CAMK2D_ST	Q14524	SCN5A	Q13557	CAMK2D	S1083	P1081A	1081	Missense	proximal	-2	no	51.699	51.244	EPSD	TCGA;COSMIC	37.605	Down-regulation
CAMK_CAMK2_CAMK2D_ST	Q14524	SCN5A	Q13557	CAMK2D	S1925	A1932V	1932	Missense	distal	7	no	51.948	51.894	EPSD	TCGA;COSMIC	37.605	Down-regulation
CAMK_CAMK2_CAMK2D_ST	Q14524	SCN5A	Q13557	CAMK2D	S1925	R1929C	1929	Missense	distal	4	no	51.948	53.164	EPSD	TCGA;COSMIC	37.605	Up-regulation
CAMK_CAMK2_CAMK2D_ST	Q14524	SCN5A	Q13557	CAMK2D	S1925	R1919C	1919	Missense	distal	-6	no	51.948	49.077	EPSD	TCGA;COSMIC	37.605	Down-regulation
CAMK_CAMK2_CAMK2D_ST	Q14524	SCN5A	Q13557	CAMK2D	S1937	G1935V	1935	Missense	proximal	-2	no	38.552	38.654	EPSD	TCGA;COSMIC	37.605	Up-regulation
CAMK_CAMK2_CAMK2D_ST	Q14524	SCN5A	Q13557	CAMK2D	S1937	A1932V	1932	Missense	distal	-5	no	38.552	37.720	EPSD	TCGA;COSMIC	37.605	Down-regulation
CAMK_CAMK2_CAMK2D_ST	Q14524	SCN5A	Q13557	CAMK2D	S1937	G1935S	1935	Missense	proximal	-2	no	38.552	38.737	EPSD	TCGA;COSMIC	37.605	Up-regulation
CAMK_CAMK2_CAMK2D_ST	Q14524	SCN5A	Q13557	CAMK2D	S1985	N1987S	1987	Missense	proximal	2	no	38.885	42.499	EPSD	TCGA	37.605	Up-regulation
CAMK_CAMK2_CAMK2D_ST	Q14524	SCN5A	Q13557	CAMK2D	S1985	N1987I	1987	Missense	proximal	2	no	38.885	43.320	EPSD	TCGA;COSMIC	37.605	Up-regulation
CAMK_CAMK2_CAMK2D_ST	Q14524	SCN5A	Q13557	CAMK2D	S1985	D1986N	1986	Missense	proximal	1	no	38.885	42.565	EPSD	TCGA;COSMIC	37.605	Up-regulation
CAMK_CAMK2_CAMK2D_ST	Q14524	SCN5A	Q13557	CAMK2D	S1985	D1978H	1978	Missense	distal	-7	no	38.885	38.632	EPSD	TCGA;COSMIC;GDSC;CCLE	37.605	Down-regulation
CAMK_CAMK2_CAMK2D_ST	Q14524	SCN5A	Q13557	CAMK2D	S1985	S1985G	1985	Missense	central	0	yes	38.885	0.000	EPSD	TCGA	37.605	Loss
CAMK_CAMK2_CAMK2D_ST	Q14524	SCN5A	Q13557	CAMK2D	S1985	R1991W	1991	Missense	distal	6	no	38.885	34.236	EPSD	TCGA;COSMIC;GDSC;CCLE	37.605	Loss
CAMK_CAMK2_CAMK2D_ST	Q14524	SCN5A	Q13557	CAMK2D	S1985	R1991Q	1991	Missense	distal	6	no	38.885	41.436	EPSD	TCGA;COSMIC;GDSC;CCLE	37.605	Up-regulation
CAMK_CAMK2_CAMK2D_ST	Q14654	KCNJ11	Q13557	CAMK2D	T224	Q218H	218	Missense	distal	-6	no	73.333	68.296	PhosphoSitePlus	TCGA;ICGC;COSMIC	37.605	Down-regulation
CAMK_CAMK2_CAMK2D_ST	Q14654	KCNJ11	Q13557	CAMK2D	T224	S225N	225	Missense	proximal	1	no	73.333	73.560	PhosphoSitePlus	TCGA;ICGC;COSMIC	37.605	Up-regulation
CAMK_CAMK2_CAMK2D_ST	Q16625	OCLN	Q13557	CAMK2D	S25	G30C	30	Missense	distal	5	no	46.884	45.450	EPSD	TCGA;ICGC;COSMIC	37.605	Down-regulation
CAMK_CAMK2_CAMK2D_ST	Q16625	OCLN	Q13557	CAMK2D	S302	D307N	307	Missense	distal	5	no	39.006	41.086	EPSD	TCGA;ICGC;COSMIC	37.605	Up-regulation
CAMK_CAMK2_CAMK2D_ST	Q16625	OCLN	Q13557	CAMK2D	S326	S327F	327	Missense	proximal	1	no	38.813	47.274	EPSD	TCGA;COSMIC	37.605	Up-regulation
CAMK_CAMK2_CAMK2D_ST	Q16625	OCLN	Q13557	CAMK2D	S370	G371D	371	Missense	proximal	1	no	54.325	49.401	EPSD	TCGA;ICGC	37.605	Down-regulation
CAMK_CAMK2_CAMK2D_ST	Q16625	OCLN	Q13557	CAMK2D	T376	G371D	371	Missense	distal	-5	no	41.386	41.259	EPSD	TCGA;ICGC	37.605	Down-regulation
CAMK_CAMK2_CAMK2D_ST	O15084	ANKRD28	Q13557	CAMK2D	T360	L358R	358	Missense	proximal	-2	no	41.180	42.088	EPSD	TCGA;ICGC;COSMIC	37.605	Up-regulation
CAMK_CAMK2_CAMK2D_ST	O15084	ANKRD28	Q13557	CAMK2D	T996	N998K	998	Missense	proximal	2	no	50.749	50.432	EPSD	TCGA;COSMIC	37.605	Down-regulation
CAMK_CAMK2_CAMK2D_ST	O15084	ANKRD28	Q13557	CAMK2D	T996	F997S	997	Missense	proximal	1	no	50.749	42.288	EPSD	TCGA	37.605	Down-regulation
CAMK_CAMK2_CAMK2D_ST	O15084	ANKRD28	Q13557	CAMK2D	T996	P991R	991	Missense	distal	-5	no	50.749	49.177	EPSD	TCGA;COSMIC	37.605	Down-regulation
CAMK_CAMK2_CAMK2D_ST	O15084	ANKRD28	Q13557	CAMK2D	T996	A999T	999	Missense	distal	3	no	50.749	37.622	EPSD	TCGA;ICGC;COSMIC	37.605	Down-regulation
CAMK_CAMK2_CAMK2D_ST	O15084	ANKRD28	Q13557	CAMK2D	S1011	E1013K	1013	Missense	proximal	2	no	71.759	67.442	PhosphoSitePlus	TCGA;ICGC;COSMIC	37.605	Down-regulation
CAMK_CAMK2_CAMK2D_ST	O15084	ANKRD28	Q13557	CAMK2D	S1011	A1014V	1014	Missense	distal	3	no	71.759	50.526	PhosphoSitePlus	TCGA;ICGC;COSMIC	37.605	Down-regulation
AGC_GRK_GRK_GRK6_ST	P07550	ADRB2	P43250	GRK6	S364	V368L	368	Missense	distal	4	no	76.187	76.110	EPSD	TCGA;ICGC;COSMIC	74.824	Down-regulation
AGC_GRK_GRK_GRK6_ST	Q16625	OCLN	P43250	GRK6	S370	G371D	371	Missense	proximal	1	no	75.195	74.287	EPSD	TCGA;ICGC	74.824	Loss
AGC_GRK_GRK_GRK6_ST	P08069	IGF1R	P43250	GRK6	S752	R753Q	753	Missense	proximal	1	no	74.919	75.353	EPSD	TCGA;ICGC;COSMIC	74.824	Up-regulation
AGC_GRK_GRK_GRK6_ST	P08069	IGF1R	P43250	GRK6	S1009	R1003W	1003	Missense	distal	-6	no	75.726	73.559	EPSD	TCGA;COSMIC	74.824	Loss
AGC_GRK_GRK_GRK6_ST	P08069	IGF1R	P43250	GRK6	S1321	R1319T	1319	Missense	proximal	-2	no	111.736	108.984	PhosphoSitePlus	TCGA;COSMIC	74.824	Down-regulation
AGC_GRK_GRK_GRK6_ST	P08069	IGF1R	P43250	GRK6	S1321	G1328D	1328	Missense	distal	7	no	111.736	112.006	PhosphoSitePlus	TCGA;COSMIC	74.824	Up-regulation
AGC_GRK_GRK_GRK6_ST	P08069	IGF1R	P43250	GRK6	S1321	A1325V	1325	Missense	distal	4	no	111.736	111.820	PhosphoSitePlus	TCGA	74.824	Up-regulation
STE_STE20_YSK_STK25_ST	Q9BUL8	PDCD10	O00506	STK25	S39	Q42H	42	Missense	distal	3	no	5.877	5.880	EPSD;PhosphoSitePlus	TCGA;ICGC;GDSC;CCLE	1.379	Up-regulation
STE_STE20_YSK_STK25_ST	Q9BUL8	PDCD10	O00506	STK25	S39	V36L	36	Missense	distal	-3	no	5.877	5.888	EPSD;PhosphoSitePlus	TCGA;ICGC	1.379	Up-regulation
STE_STE20_YSK_STK25_ST	Q9BUL8	PDCD10	O00506	STK25	S39	L33V	33	Missense	distal	-6	no	5.877	5.842	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	1.379	Down-regulation
STE_STE20_YSK_STK25_ST	Q9BUL8	PDCD10	O00506	STK25	T43	Q42H	42	Missense	proximal	-1	no	5.560	5.506	PhosphoSitePlus;EPSD	TCGA;ICGC;GDSC;CCLE	1.379	Down-regulation
STE_STE20_YSK_STK25_ST	Q9BUL8	PDCD10	O00506	STK25	T43	V36L	36	Missense	distal	-7	no	5.560	5.561	PhosphoSitePlus;EPSD	TCGA;ICGC	1.379	Up-regulation
TK_VEGFR_FLT1_Y	P17948	FLT1	P17948	FLT1	Y1053	R1055K	1055	Missense	proximal	2	no	1.851	1.855	EPSD	TCGA;COSMIC	1.801	Up-regulation
TK_VEGFR_FLT1_Y	P17948	FLT1	P17948	FLT1	Y1053	D1052N	1052	Missense	proximal	-1	no	1.851	1.866	EPSD	TCGA;COSMIC;GDSC;CCLE	1.801	Up-regulation
TK_VEGFR_FLT1_Y	P17948	FLT1	P17948	FLT1	Y1169	V1162E	1162	Missense	distal	-7	no	5.215	5.199	EPSD;PhosphoSitePlus	TCGA;COSMIC	1.801	Down-regulation
TK_VEGFR_FLT1_Y	P17948	FLT1	P17948	FLT1	Y1169	P1171S	1171	Missense	proximal	2	no	5.215	5.236	EPSD;PhosphoSitePlus	TCGA;COSMIC	1.801	Up-regulation
TK_VEGFR_FLT1_Y	P17948	FLT1	P17948	FLT1	Y1213	M1220I	1220	Missense	distal	7	no	5.316	5.296	EPSD;PhosphoSitePlus	TCGA;COSMIC	1.801	Down-regulation
TK_VEGFR_FLT1_Y	P17948	FLT1	P17948	FLT1	Y1213	F1219I	1219	Missense	distal	6	no	5.316	5.057	EPSD;PhosphoSitePlus	TCGA;COSMIC	1.801	Down-regulation
TK_VEGFR_FLT1_Y	P17948	FLT1	P17948	FLT1	Y1213	R1212I	1212	Missense	proximal	-1	no	5.316	5.340	EPSD;PhosphoSitePlus	TCGA	1.801	Up-regulation
TK_VEGFR_FLT1_Y	P17948	FLT1	P17948	FLT1	Y1242	G1244D	1244	Missense	proximal	2	no	5.055	5.058	EPSD;PhosphoSitePlus	TCGA;COSMIC;GDSC	1.801	Up-regulation
TK_VEGFR_FLT1_Y	P17948	FLT1	P17948	FLT1	Y1242	D1245N	1245	Missense	distal	3	no	5.055	4.866	EPSD;PhosphoSitePlus	TCGA;COSMIC	1.801	Down-regulation
TK_VEGFR_FLT1_Y	P17948	FLT1	P17948	FLT1	Y1242	T1236S	1236	Missense	distal	-6	no	5.055	5.049	EPSD;PhosphoSitePlus	TCGA;COSMIC	1.801	Down-regulation
TK_VEGFR_FLT1_Y	P17948	FLT1	P17948	FLT1	Y1309	D1310G	1310	Missense	proximal	1	no	4.757	4.769	EPSD	TCGA;COSMIC	1.801	Up-regulation
TK_VEGFR_FLT1_Y	P17948	FLT1	P17948	FLT1	Y1309	Y1309H	1309	Missense	central	0	yes	4.757	0.000	EPSD	TCGA;COSMIC	1.801	Loss
TK_VEGFR_FLT1_Y	P17948	FLT1	P17948	FLT1	Y1309	E1315K	1315	Missense	distal	6	no	4.757	4.526	EPSD	TCGA;COSMIC	1.801	Down-regulation
Other_WNK_WNK3_ST	Q9H4A3	WNK1	Q9BYP7	WNK3	T72	T74A	74	Missense	proximal	2	no	4.561	4.661	EPSD	TCGA;ICGC;COSMIC	2.233	Up-regulation
Other_WNK_WNK3_ST	Q9H4A3	WNK1	Q9BYP7	WNK3	S170	V172E	172	Missense	proximal	2	no	2.460	2.245	EPSD	TCGA;ICGC;COSMIC	2.233	Down-regulation
Other_WNK_WNK3_ST	Q9H4A3	WNK1	Q9BYP7	WNK3	T209	G213E	213	Missense	distal	4	no	2.846	3.154	EPSD	TCGA;ICGC;COSMIC	2.233	Up-regulation
Other_WNK_WNK3_ST	Q9H4A3	WNK1	Q9BYP7	WNK3	S215	G213E	213	Missense	proximal	-2	no	2.069	2.377	EPSD	TCGA;ICGC;COSMIC	2.233	Gain
Other_WNK_WNK3_ST	Q9H4A3	WNK1	Q9BYP7	WNK3	S382	E388Q	388	Missense	distal	6	no	6.659	6.512	PhosphoSitePlus	TCGA;ICGC;COSMIC	2.233	Down-regulation
Other_WNK_WNK3_ST	Q9H4A3	WNK1	Q9BYP7	WNK3	S382	R376W	376	Missense	distal	-6	no	6.659	6.441	PhosphoSitePlus	TCGA;ICGC	2.233	Down-regulation
Other_WNK_WNK3_ST	Q9H4A3	WNK1	Q9BYP7	WNK3	T436	R433L	433	Missense	distal	-3	no	2.350	2.492	EPSD	TCGA;ICGC;COSMIC	2.233	Up-regulation
Other_WNK_WNK3_ST	Q9H4A3	WNK1	Q9BYP7	WNK3	T436	R434H	434	Missense	proximal	-2	no	2.350	3.122	EPSD	TCGA;ICGC;COSMIC	2.233	Up-regulation
Other_WNK_WNK3_ST	Q9H4A3	WNK1	Q9BYP7	WNK3	S563	I558M	558	Missense	distal	-5	no	2.126	2.261	EPSD	TCGA;COSMIC	2.233	Gain
Other_WNK_WNK3_ST	Q9H4A3	WNK1	Q9BYP7	WNK3	S597	A598V	598	Missense	proximal	1	no	3.602	3.995	EPSD	TCGA;COSMIC	2.233	Up-regulation
Other_WNK_WNK3_ST	Q9H4A3	WNK1	Q9BYP7	WNK3	S1289	H1296D	1296	Missense	distal	7	no	2.660	2.884	EPSD	TCGA;COSMIC	2.233	Up-regulation
Other_WNK_WNK3_ST	Q9H4A3	WNK1	Q9BYP7	WNK3	S1289	S1289N	1289	Missense	central	0	yes	2.660	0.000	EPSD	TCGA	2.233	Loss
Other_WNK_WNK3_ST	Q9H4A3	WNK1	Q9BYP7	WNK3	T1913	S1918F	1918	Missense	distal	5	no	2.817	2.792	EPSD	TCGA;COSMIC	2.233	Down-regulation
Other_WNK_WNK3_ST	Q9H4A3	WNK1	Q9BYP7	WNK3	T1928	A1925V	1925	Missense	distal	-3	no	2.931	2.939	EPSD	TCGA;COSMIC	2.233	Up-regulation
Other_WNK_WNK3_ST	Q9H4A3	WNK1	Q9BYP7	WNK3	S1959	R1957H	1957	Missense	proximal	-2	no	2.062	2.835	EPSD	TCGA;COSMIC	2.233	Gain
Other_WNK_WNK3_ST	Q9H4A3	WNK1	Q9BYP7	WNK3	T1970	A1977V	1977	Missense	distal	7	no	2.745	2.677	EPSD	TCGA;COSMIC	2.233	Down-regulation
Other_WNK_WNK3_ST	Q9H4A3	WNK1	Q9BYP7	WNK3	T1970	T1970P	1970	Missense	central	0	yes	2.745	0.000	EPSD	TCGA;COSMIC	2.233	Loss
Other_WNK_WNK3_ST	Q9H4A3	WNK1	Q9BYP7	WNK3	T1970	K1972N	1972	Missense	proximal	2	no	2.745	2.719	EPSD	TCGA;COSMIC	2.233	Down-regulation
Other_WNK_WNK3_ST	Q9H4A3	WNK1	Q9BYP7	WNK3	S2037	Q2044H	2044	Missense	distal	7	no	2.251	2.114	EPSD	TCGA;COSMIC	2.233	Loss
Other_WNK_WNK3_ST	Q9H4A3	WNK1	Q9BYP7	WNK3	S2037	Q2035H	2035	Missense	proximal	-2	no	2.251	2.531	EPSD	TCGA;COSMIC	2.233	Up-regulation
Other_WNK_WNK3_ST	Q9H4A3	WNK1	Q9BYP7	WNK3	T2245	H2251P	2251	Missense	distal	6	no	3.613	3.834	EPSD	TCGA;COSMIC	2.233	Up-regulation
Other_WNK_WNK3_ST	Q9H4A3	WNK1	Q9BYP7	WNK3	T2245	T2239M	2239	Missense	distal	-6	no	3.613	3.463	EPSD	TCGA;COSMIC	2.233	Down-regulation
Other_WNK_WNK3_ST	Q9H4A3	WNK1	Q9BYP7	WNK3	S2370	S2370F	2370	Missense	central	0	yes	2.286	0.000	EPSD	TCGA;COSMIC	2.233	Loss
Other_WNK_WNK3_ST	Q9UHW9	SLC12A6	Q9BYP7	WNK3	S96	S96P	96	Missense	central	0	yes	6.778	0.000	EPSD;PhosphoSitePlus	TCGA;COSMIC	2.233	Loss
Other_WNK_WNK3_ST	Q9UHW9	SLC12A6	Q9BYP7	WNK3	S120	E127K	127	Missense	distal	7	no	3.253	3.201	EPSD	TCGA;COSMIC	2.233	Down-regulation
Other_WNK_WNK3_ST	Q9UHW9	SLC12A6	Q9BYP7	WNK3	S120	R113Q	113	Missense	distal	-7	no	3.253	3.008	EPSD	TCGA	2.233	Down-regulation
Other_WNK_WNK3_ST	Q9UHW9	SLC12A6	Q9BYP7	WNK3	S148	L150F	150	Missense	proximal	2	no	2.255	2.187	EPSD	TCGA;COSMIC	2.233	Loss
Other_WNK_WNK3_ST	Q9UHW9	SLC12A6	Q9BYP7	WNK3	S148	R152C	152	Missense	distal	4	no	2.255	2.361	EPSD	TCGA;COSMIC	2.233	Up-regulation
Other_WNK_WNK3_ST	Q9UHW9	SLC12A6	Q9BYP7	WNK3	T182	T187I	187	Missense	distal	5	no	2.371	2.172	EPSD	TCGA;COSMIC	2.233	Loss
Other_WNK_WNK3_ST	Q9UHW9	SLC12A6	Q9BYP7	WNK3	T182	K177N	177	Missense	distal	-5	no	2.371	2.335	EPSD	TCGA;COSMIC	2.233	Down-regulation
Other_WNK_WNK3_ST	Q9UHW9	SLC12A6	Q9BYP7	WNK3	T991	E995K	995	Missense	distal	4	no	7.155	7.083	EPSD;PhosphoSitePlus	TCGA;COSMIC	2.233	Down-regulation
Other_WNK_WNK3_ST	Q9UHW9	SLC12A6	Q9BYP7	WNK3	T991	R990H	990	Missense	proximal	-1	no	7.155	7.012	EPSD;PhosphoSitePlus	TCGA;COSMIC	2.233	Down-regulation
Other_WNK_WNK3_ST	Q9UHW9	SLC12A6	Q9BYP7	WNK3	T1028	R1026P	1026	Missense	proximal	-2	no	2.932	2.854	EPSD	TCGA;COSMIC	2.233	Down-regulation
Other_WNK_WNK3_ST	Q9UHW9	SLC12A6	Q9BYP7	WNK3	T1038	E1036K	1036	Missense	proximal	-2	no	2.422	2.124	EPSD	TCGA;COSMIC	2.233	Loss
Other_WNK_WNK3_ST	Q9UHW9	SLC12A6	Q9BYP7	WNK3	T1129	E1130V	1130	Missense	proximal	1	no	2.438	2.877	EPSD	TCGA;COSMIC	2.233	Up-regulation
TKL_RIPK_RIPK2_ST	O43353	RIPK2	O43353	RIPK2	S174	R179Q	179	Missense	distal	5	no	7.284	7.217	PhosphoSitePlus;EPSD	TCGA;COSMIC;CCLE	3.253	Down-regulation
TKL_RIPK_RIPK2_ST	O43353	RIPK2	O43353	RIPK2	S174	R171C	171	Missense	distal	-3	no	7.284	7.273	PhosphoSitePlus;EPSD	TCGA;COSMIC	3.253	Down-regulation
TKL_RIPK_RIPK2_ST	O43353	RIPK2	O43353	RIPK2	S174	S174P	174	Missense	central	0	yes	7.284	0.000	PhosphoSitePlus;EPSD	TCGA;COSMIC	3.253	Loss
TKL_RIPK_RIPK2_ST	O43353	RIPK2	O43353	RIPK2	S176	R179Q	179	Missense	distal	3	no	7.813	7.724	EPSD;PhosphoSitePlus	TCGA;COSMIC;CCLE	3.253	Down-regulation
TKL_RIPK_RIPK2_ST	O43353	RIPK2	O43353	RIPK2	S176	R171C	171	Missense	distal	-5	no	7.813	7.774	EPSD;PhosphoSitePlus	TCGA;COSMIC	3.253	Down-regulation
TKL_RIPK_RIPK2_ST	O43353	RIPK2	O43353	RIPK2	S176	S174P	174	Missense	proximal	-2	no	7.813	6.873	EPSD;PhosphoSitePlus	TCGA;COSMIC	3.253	Down-regulation
TKL_RIPK_RIPK2_ST	O43353	RIPK2	O43353	RIPK2	S178	R179Q	179	Missense	proximal	1	no	8.332	8.272	EPSD;PhosphoSitePlus	TCGA;COSMIC;CCLE	3.253	Down-regulation
TKL_RIPK_RIPK2_ST	O43353	RIPK2	O43353	RIPK2	S178	R171C	171	Missense	distal	-7	no	8.332	8.253	EPSD;PhosphoSitePlus	TCGA;COSMIC	3.253	Down-regulation
TKL_RIPK_RIPK2_ST	O43353	RIPK2	O43353	RIPK2	S178	S174P	174	Missense	distal	-4	no	8.332	8.312	EPSD;PhosphoSitePlus	TCGA;COSMIC	3.253	Down-regulation
TKL_RIPK_RIPK2_ST	O43353	RIPK2	O43353	RIPK2	S180	R179Q	179	Missense	proximal	-1	no	6.922	6.877	EPSD;PhosphoSitePlus	TCGA;COSMIC;CCLE	3.253	Down-regulation
TKL_RIPK_RIPK2_ST	O43353	RIPK2	O43353	RIPK2	S180	S174P	174	Missense	distal	-6	no	6.922	6.867	EPSD;PhosphoSitePlus	TCGA;COSMIC	3.253	Down-regulation
TKL_RIPK_RIPK2_ST	O43353	RIPK2	O43353	RIPK2	S181	R179Q	179	Missense	proximal	-2	no	7.197	6.996	EPSD;PhosphoSitePlus	TCGA;COSMIC;CCLE	3.253	Down-regulation
TKL_RIPK_RIPK2_ST	O43353	RIPK2	O43353	RIPK2	S181	S174P	174	Missense	distal	-7	no	7.197	6.998	EPSD;PhosphoSitePlus	TCGA;COSMIC	3.253	Down-regulation
TKL_RIPK_RIPK2_ST	O43353	RIPK2	O43353	RIPK2	S183	I190M	190	Missense	distal	7	no	3.050	3.609	EPSD	TCGA;COSMIC	3.253	Gain
TKL_RIPK_RIPK2_ST	O43353	RIPK2	O43353	RIPK2	S348	Q350K	350	Missense	proximal	2	no	2.475	3.327	EPSD	TCGA;COSMIC	3.253	Gain
TKL_RIPK_RIPK2_ST	O43353	RIPK2	O43353	RIPK2	S355	E353K	353	Missense	proximal	-2	no	3.770	4.402	EPSD	TCGA;COSMIC	3.253	Up-regulation
TKL_RIPK_RIPK2_ST	O43353	RIPK2	O43353	RIPK2	S355	G356S	356	Missense	proximal	1	no	3.770	3.947	EPSD	TCGA;COSMIC	3.253	Up-regulation
TKL_RIPK_RIPK2_ST	O43353	RIPK2	O43353	RIPK2	S355	Q350K	350	Missense	distal	-5	no	3.770	3.804	EPSD	TCGA;COSMIC	3.253	Up-regulation
TKL_RIPK_RIPK2_ST	O43353	RIPK2	O43353	RIPK2	S355	S355G	355	Missense	central	0	yes	3.770	0.000	EPSD	TCGA;COSMIC	3.253	Loss
TKL_RIPK_RIPK2_ST	O43353	RIPK2	O43353	RIPK2	S355	S355C	355	Missense	central	0	yes	3.770	0.000	EPSD	TCGA;COSMIC	3.253	Loss
TKL_RIPK_RIPK2_ST	O43353	RIPK2	O43353	RIPK2	S361	G356S	356	Missense	distal	-5	no	3.262	3.362	EPSD	TCGA;COSMIC	3.253	Up-regulation
TKL_RIPK_RIPK2_ST	O43353	RIPK2	O43353	RIPK2	S361	S355G	355	Missense	distal	-6	no	3.262	3.206	EPSD	TCGA;COSMIC	3.253	Loss
TKL_RIPK_RIPK2_ST	O43353	RIPK2	O43353	RIPK2	S361	S355C	355	Missense	distal	-6	no	3.262	3.194	EPSD	TCGA;COSMIC	3.253	Loss
TKL_RIPK_RIPK2_ST	O43353	RIPK2	O43353	RIPK2	S361	P367S	367	Missense	distal	6	no	3.262	3.432	EPSD	TCGA;COSMIC	3.253	Up-regulation
TKL_RIPK_RIPK2_ST	O43353	RIPK2	O43353	RIPK2	S399	F406L	406	Missense	distal	7	no	3.451	3.386	EPSD	TCGA;COSMIC	3.253	Down-regulation
TKL_RIPK_RIPK2_ST	O43353	RIPK2	O43353	RIPK2	S529	S529L	529	Missense	central	0	yes	3.905	0.000	EPSD	TCGA;COSMIC	3.253	Loss
TKL_RIPK_RIPK2_ST	O43353	RIPK2	O43353	RIPK2	S529	S529P	529	Missense	central	0	yes	3.905	0.000	EPSD	TCGA;COSMIC	3.253	Loss
TKL_RIPK_RIPK2_ST	O43353	RIPK2	O43353	RIPK2	S529	L534V	534	Missense	distal	5	no	3.905	3.930	EPSD	TCGA	3.253	Up-regulation
TK_InsR_IGF1R_Y	P35568	IRS1	P08069	IGF1R	Y47	R54W	54	Missense	distal	7	no	3.370	3.389	EPSD	TCGA;ICGC;COSMIC	3.025	Up-regulation
TK_InsR_IGF1R_Y	P35568	IRS1	P08069	IGF1R	Y47	Y46H	46	Missense	proximal	-1	no	3.370	3.411	EPSD	TCGA;ICGC;COSMIC	3.025	Up-regulation
TK_InsR_IGF1R_Y	P35568	IRS1	P08069	IGF1R	Y47	A42V	42	Missense	distal	-5	no	3.370	3.396	EPSD	TCGA;ICGC;COSMIC	3.025	Up-regulation
TK_InsR_IGF1R_Y	P35568	IRS1	P08069	IGF1R	Y47	A42T	42	Missense	distal	-5	no	3.370	3.335	EPSD	TCGA;ICGC;COSMIC	3.025	Down-regulation
TK_InsR_IGF1R_Y	P35568	IRS1	P08069	IGF1R	Y431	S428L	428	Missense	distal	-3	no	4.578	3.669	EPSD	TCGA;ICGC;COSMIC	3.025	Down-regulation
TK_InsR_IGF1R_Y	P35568	IRS1	P08069	IGF1R	Y431	G424S	424	Missense	distal	-7	no	4.578	4.203	EPSD	TCGA;ICGC;COSMIC	3.025	Down-regulation
TK_InsR_IGF1R_Y	P35568	IRS1	P08069	IGF1R	Y431	F438V	438	Missense	distal	7	no	4.578	4.508	EPSD	TCGA;ICGC;COSMIC	3.025	Down-regulation
TK_InsR_IGF1R_Y	P35568	IRS1	P08069	IGF1R	Y612	H607R	607	Missense	distal	-5	no	5.097	5.047	EPSD	TCGA;ICGC	3.025	Down-regulation
TK_InsR_IGF1R_Y	P35568	IRS1	P08069	IGF1R	Y612	G611C	611	Missense	proximal	-1	no	5.097	5.071	EPSD	TCGA;ICGC;COSMIC	3.025	Down-regulation
TK_InsR_IGF1R_Y	P35568	IRS1	P08069	IGF1R	Y732	M733I	733	Missense	proximal	1	no	3.821	3.194	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	3.025	Down-regulation
TK_InsR_IGF1R_Y	P35568	IRS1	P08069	IGF1R	Y732	C728Y	728	Missense	distal	-4	no	3.821	3.802	EPSD;PhosphoSitePlus	TCGA;COSMIC	3.025	Down-regulation
TK_InsR_IGF1R_Y	P35568	IRS1	P08069	IGF1R	Y732	D731E	731	Missense	proximal	-1	no	3.821	3.828	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	3.025	Up-regulation
TK_InsR_IGF1R_Y	P35568	IRS1	P08069	IGF1R	Y764	S770Y	770	Missense	distal	6	no	3.961	3.798	EPSD	TCGA;ICGC;COSMIC	3.025	Down-regulation
TK_InsR_IGF1R_Y	P35568	IRS1	P08069	IGF1R	Y764	R769K	769	Missense	distal	5	no	3.961	4.028	EPSD	TCGA;ICGC;COSMIC	3.025	Up-regulation
TK_InsR_IGF1R_Y	P35568	IRS1	P08069	IGF1R	Y896	E900A	900	Missense	distal	4	no	5.717	5.786	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	3.025	Up-regulation
TK_InsR_IGF1R_Y	P35568	IRS1	P08069	IGF1R	Y896	P890S	890	Missense	distal	-6	no	5.717	5.708	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	3.025	Down-regulation
TK_InsR_IGF1R_Y	P35568	IRS1	P08069	IGF1R	Y941	E939Q	939	Missense	proximal	-2	no	5.533	5.579	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	3.025	Up-regulation
TK_InsR_IGF1R_Y	P35568	IRS1	P08069	IGF1R	Y941	E939K	939	Missense	proximal	-2	no	5.533	5.505	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	3.025	Down-regulation
TK_InsR_IGF1R_Y	P35568	IRS1	P08069	IGF1R	Y989	R986W	986	Missense	distal	-3	no	7.413	7.030	PhosphoSitePlus;EPSD	TCGA;ICGC;COSMIC;GDSC;CCLE	3.025	Down-regulation
TK_InsR_IGF1R_Y	P35568	IRS1	P08069	IGF1R	Y1001	S1005L	1005	Missense	distal	4	no	3.560	2.716	EPSD	TCGA;ICGC	3.025	Loss
TK_InsR_IGF1R_Y	P35568	IRS1	P08069	IGF1R	Y1012	S1005L	1005	Missense	distal	-7	no	2.680	3.370	EPSD	TCGA;ICGC	3.025	Gain
TK_InsR_IGF1R_Y	P35568	IRS1	P08069	IGF1R	Y1179	I1180M	1180	Missense	proximal	1	no	3.926	4.553	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	3.025	Up-regulation
TK_InsR_IGF1R_Y	P35568	IRS1	P08069	IGF1R	Y1179	G1176S	1176	Missense	distal	-3	no	3.926	4.582	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	3.025	Up-regulation
TK_InsR_IGF1R_Y	P08069	IGF1R	P08069	IGF1R	Y973	P978S	978	Missense	distal	5	no	5.707	5.838	EPSD	TCGA;COSMIC	3.025	Up-regulation
TK_InsR_IGF1R_Y	P08069	IGF1R	P08069	IGF1R	Y973	P978L	978	Missense	distal	5	no	5.707	5.583	EPSD	TCGA;COSMIC	3.025	Down-regulation
TK_InsR_IGF1R_Y	P08069	IGF1R	P08069	IGF1R	Y980	P978S	978	Missense	proximal	-2	no	5.088	5.699	PhosphoSitePlus;EPSD	TCGA;COSMIC	3.025	Up-regulation
TK_InsR_IGF1R_Y	P08069	IGF1R	P08069	IGF1R	Y980	P978L	978	Missense	proximal	-2	no	5.088	5.008	PhosphoSitePlus;EPSD	TCGA;COSMIC	3.025	Down-regulation
TK_InsR_IGF1R_Y	P08069	IGF1R	P08069	IGF1R	Y1161	Y1161C	1161	Missense	central	0	yes	3.599	0.000	EPSD;PhosphoSitePlus	TCGA;COSMIC	3.025	Loss
TK_InsR_IGF1R_Y	P08069	IGF1R	P08069	IGF1R	Y1161	R1167Q	1167	Missense	distal	6	no	3.599	3.675	EPSD;PhosphoSitePlus	TCGA	3.025	Up-regulation
TK_InsR_IGF1R_Y	P08069	IGF1R	P08069	IGF1R	Y1161	T1157M	1157	Missense	distal	-4	no	3.599	3.577	EPSD;PhosphoSitePlus	TCGA	3.025	Down-regulation
TK_InsR_IGF1R_Y	P08069	IGF1R	P08069	IGF1R	Y1165	Y1161C	1161	Missense	distal	-4	no	5.207	5.226	EPSD;PhosphoSitePlus	TCGA;COSMIC	3.025	Up-regulation
TK_InsR_IGF1R_Y	P08069	IGF1R	P08069	IGF1R	Y1165	R1167Q	1167	Missense	proximal	2	no	5.207	5.292	EPSD;PhosphoSitePlus	TCGA	3.025	Up-regulation
TK_InsR_IGF1R_Y	P08069	IGF1R	P08069	IGF1R	Y1165	G1170W	1170	Missense	distal	5	no	5.207	5.153	EPSD;PhosphoSitePlus	TCGA;COSMIC	3.025	Down-regulation
TK_InsR_IGF1R_Y	P08069	IGF1R	P08069	IGF1R	Y1166	Y1161C	1161	Missense	distal	-5	no	5.167	5.128	EPSD;PhosphoSitePlus	TCGA;COSMIC	3.025	Down-regulation
TK_InsR_IGF1R_Y	P08069	IGF1R	P08069	IGF1R	Y1166	R1167Q	1167	Missense	proximal	1	no	5.167	5.339	EPSD;PhosphoSitePlus	TCGA	3.025	Up-regulation
TK_InsR_IGF1R_Y	P08069	IGF1R	P08069	IGF1R	Y1166	G1170W	1170	Missense	distal	4	no	5.167	4.797	EPSD;PhosphoSitePlus	TCGA;COSMIC	3.025	Down-regulation
TK_InsR_IGF1R_Y	Q03431	PTH1R	P08069	IGF1R	Y494	G490R	490	Missense	distal	-4	no	4.394	4.390	PhosphoSitePlus	TCGA;ICGC;COSMIC;GDSC;CCLE	3.025	Down-regulation
TK_InsR_IGF1R_Y	Q03431	PTH1R	P08069	IGF1R	Y494	S491R	491	Missense	distal	-3	no	4.394	4.001	PhosphoSitePlus	TCGA;ICGC;COSMIC	3.025	Down-regulation
TK_InsR_IGF1R_Y	Q03431	PTH1R	P08069	IGF1R	Y494	P498L	498	Missense	distal	4	no	4.394	3.856	PhosphoSitePlus	TCGA;ICGC;COSMIC	3.025	Down-regulation
TK_InsR_IGF1R_Y	Q03431	PTH1R	P08069	IGF1R	Y494	R488C	488	Missense	distal	-6	no	4.394	4.420	PhosphoSitePlus	TCGA;ICGC;COSMIC	3.025	Up-regulation
TK_InsR_IGF1R_Y	Q03431	PTH1R	P08069	IGF1R	Y496	G490R	490	Missense	distal	-6	no	3.200	3.248	EPSD	TCGA;ICGC;COSMIC;GDSC;CCLE	3.025	Up-regulation
TK_InsR_IGF1R_Y	Q03431	PTH1R	P08069	IGF1R	Y496	S491R	491	Missense	distal	-5	no	3.200	3.344	EPSD	TCGA;ICGC;COSMIC	3.025	Up-regulation
TK_InsR_IGF1R_Y	Q03431	PTH1R	P08069	IGF1R	Y496	T503K	503	Missense	distal	7	no	3.200	3.209	EPSD	TCGA;ICGC;COSMIC	3.025	Up-regulation
TK_InsR_IGF1R_Y	Q03431	PTH1R	P08069	IGF1R	Y496	P498L	498	Missense	proximal	2	no	3.200	1.465	EPSD	TCGA;ICGC;COSMIC	3.025	Loss
TK_InsR_IGF1R_Y	P07355	ANXA2	P08069	IGF1R	Y24	K28M	28	Missense	distal	4	no	3.818	3.764	PhosphoSitePlus	TCGA;COSMIC	3.025	Down-regulation
TK_InsR_IGF1R_Y	P12004	PCNA	P08069	IGF1R	Y60	A67P	67	Missense	distal	7	no	4.859	4.864	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	3.025	Up-regulation
TK_InsR_IGF1R_Y	P12004	PCNA	P08069	IGF1R	Y60	A67T	67	Missense	distal	7	no	4.859	4.858	EPSD;PhosphoSitePlus	TCGA;ICGC	3.025	Down-regulation
TK_InsR_IGF1R_Y	P12004	PCNA	P08069	IGF1R	Y114	D120N	120	Missense	distal	6	no	3.957	3.979	EPSD	TCGA;ICGC;COSMIC	3.025	Up-regulation
TK_InsR_IGF1R_Y	P12004	PCNA	P08069	IGF1R	Y114	E109D	109	Missense	distal	-5	no	3.957	4.002	EPSD	TCGA;ICGC;COSMIC	3.025	Up-regulation
TK_InsR_IGF1R_Y	P12004	PCNA	P08069	IGF1R	Y250	M244I	244	Missense	distal	-6	no	2.940	3.029	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	3.025	Gain
TK_InsR_IGF1R_Y	P12004	PCNA	P08069	IGF1R	Y250	M244R	244	Missense	distal	-6	no	2.940	3.034	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	3.025	Gain
TK_InsR_IGF1R_Y	P78324	SIRPA	P08069	IGF1R	Y470	A471V	471	Missense	proximal	1	no	4.343	4.102	EPSD;PhosphoSitePlus	TCGA;ICGC	3.025	Down-regulation
TK_InsR_IGF1R_Y	P78324	SIRPA	P08069	IGF1R	Y470	A463V	463	Missense	distal	-7	no	4.343	4.400	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	3.025	Up-regulation
TK_InsR_IGF1R_Y	P78324	SIRPA	P08069	IGF1R	Y496	R503W	503	Missense	distal	7	no	3.937	3.956	PhosphoSitePlus;EPSD	TCGA;ICGC;COSMIC	3.025	Up-regulation
TK_InsR_IGF1R_Y	P78324	SIRPA	P08069	IGF1R	Y496	P489L	489	Missense	distal	-7	no	3.937	4.368	PhosphoSitePlus;EPSD	TCGA;ICGC;COSMIC	3.025	Up-regulation
TK_InsR_IGF1R_Y	P78324	SIRPA	P08069	IGF1R	Y496	S492Y	492	Missense	distal	-4	no	3.937	3.819	PhosphoSitePlus;EPSD	TCGA;ICGC;COSMIC	3.025	Down-regulation
TKL_MLK_MLK_MAP3K10_ST	Q92630	DYRK2	Q02779	MAP3K10	S30	A29S	29	Missense	proximal	-1	no	2.138	2.139	EPSD	TCGA;ICGC;COSMIC	2.080	Up-regulation
TKL_MLK_MLK_MAP3K10_ST	Q92630	DYRK2	Q02779	MAP3K10	S30	S30F	30	Missense	central	0	yes	2.138	0.000	EPSD	TCGA;ICGC;COSMIC	2.080	Loss
TKL_MLK_MLK_MAP3K10_ST	Q92630	DYRK2	Q02779	MAP3K10	S48	P49L	49	Missense	proximal	1	no	2.449	0.015	EPSD	TCGA;ICGC	2.080	Loss
TKL_MLK_MLK_MAP3K10_ST	Q92630	DYRK2	Q02779	MAP3K10	T381	R378H	378	Missense	distal	-3	no	5.704	5.595	PhosphoSitePlus;EPSD	TCGA;ICGC;COSMIC	2.080	Down-regulation
TKL_MLK_MLK_MAP3K10_ST	Q92630	DYRK2	Q02779	MAP3K10	T381	R378C	378	Missense	distal	-3	no	5.704	5.453	PhosphoSitePlus;EPSD	TCGA;ICGC;COSMIC	2.080	Down-regulation
TKL_MLK_MLK_MAP3K10_ST	Q92630	DYRK2	Q02779	MAP3K10	T381	T381M	381	Missense	central	0	yes	5.704	0.000	PhosphoSitePlus;EPSD	TCGA;ICGC;COSMIC	2.080	Loss
TKL_MLK_MLK_MAP3K10_ST	Q92630	DYRK2	Q02779	MAP3K10	S385	R378H	378	Missense	distal	-7	no	3.184	3.248	EPSD	TCGA;ICGC;COSMIC	2.080	Up-regulation
TKL_MLK_MLK_MAP3K10_ST	Q92630	DYRK2	Q02779	MAP3K10	S385	R378C	378	Missense	distal	-7	no	3.184	3.269	EPSD	TCGA;ICGC;COSMIC	2.080	Up-regulation
TKL_MLK_MLK_MAP3K10_ST	Q92630	DYRK2	Q02779	MAP3K10	S385	E392V	392	Missense	distal	7	no	3.184	3.349	EPSD	TCGA;ICGC;COSMIC	2.080	Up-regulation
TKL_MLK_MLK_MAP3K10_ST	Q92630	DYRK2	Q02779	MAP3K10	S385	T381M	381	Missense	distal	-4	no	3.184	3.157	EPSD	TCGA;ICGC;COSMIC	2.080	Down-regulation
TKL_MLK_MLK_MAP3K10_ST	Q92630	DYRK2	Q02779	MAP3K10	S449	V456G	456	Missense	distal	7	no	6.181	6.038	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	2.080	Down-regulation
TKL_MLK_MLK_MAP3K10_ST	Q92630	DYRK2	Q02779	MAP3K10	S449	D447G	447	Missense	proximal	-2	no	6.181	6.178	EPSD;PhosphoSitePlus	TCGA;ICGC	2.080	Down-regulation
TKL_MLK_MLK_MAP3K10_ST	Q92630	DYRK2	Q02779	MAP3K10	S449	N454H	454	Missense	distal	5	no	6.181	6.158	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	2.080	Down-regulation
TKL_MLK_MLK_MAP3K10_ST	Q92630	DYRK2	Q02779	MAP3K10	S449	R451Q	451	Missense	proximal	2	no	6.181	6.101	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC;CCLE	2.080	Down-regulation
TKL_MLK_MLK_MAP3K10_ST	P15923	TCF3	Q02779	MAP3K10	S139	S134N	134	Missense	distal	-5	no	2.922	3.093	EPSD	TCGA;ICGC;COSMIC	2.080	Up-regulation
TKL_MLK_MLK_MAP3K10_ST	P15923	TCF3	Q02779	MAP3K10	T168	T168M	168	Missense	central	0	yes	2.130	0.000	EPSD	TCGA;ICGC;COSMIC	2.080	Loss
TKL_MLK_MLK_MAP3K10_ST	P15923	TCF3	Q02779	MAP3K10	T168	V173F	173	Missense	distal	5	no	2.130	2.161	EPSD	TCGA;ICGC;COSMIC	2.080	Up-regulation
TKL_MLK_MLK_MAP3K10_ST	P15923	TCF3	Q02779	MAP3K10	T168	G164D	164	Missense	distal	-4	no	2.130	2.088	EPSD	TCGA;ICGC;COSMIC	2.080	Down-regulation
TKL_MLK_MLK_MAP3K10_ST	P15923	TCF3	Q02779	MAP3K10	T168	A162T	162	Missense	distal	-6	no	2.130	2.224	EPSD	TCGA;ICGC	2.080	Up-regulation
TKL_MLK_MLK_MAP3K10_ST	P15923	TCF3	Q02779	MAP3K10	T308	D315N	315	Missense	distal	7	no	3.595	3.764	EPSD	TCGA;ICGC;COSMIC	2.080	Up-regulation
TKL_MLK_MLK_MAP3K10_ST	P15923	TCF3	Q02779	MAP3K10	S379	G376S	376	Missense	distal	-3	no	5.985	6.006	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	2.080	Up-regulation
AGC_DMPK_GEK_DMPK_ST	P11831	SRF	Q09013	DMPK	T217	T217I	217	Missense	central	0	yes	2.565	0.000	EPSD	TCGA;COSMIC	2.483	Loss
AGC_DMPK_GEK_DMPK_ST	P11831	SRF	Q09013	DMPK	S253	E252K	252	Missense	proximal	-1	no	2.947	2.945	EPSD	TCGA;COSMIC	2.483	Down-regulation
AGC_DMPK_GEK_DMPK_ST	P11831	SRF	Q09013	DMPK	S253	L246F	246	Missense	distal	-7	no	2.947	2.978	EPSD	TCGA;ICGC;COSMIC	2.483	Up-regulation
TKL_STKR_STKR2_TGFBR2_ST	P36897	TGFBR1	P37173	TGFBR2	S165	P164A	164	Missense	proximal	-1	no	1.496	1.466	EPSD	TCGA;ICGC;COSMIC	0.983	Down-regulation
TKL_STKR_STKR2_TGFBR2_ST	P36897	TGFBR1	P37173	TGFBR2	T185	T186M	186	Missense	proximal	1	no	1.780	1.775	PhosphoSitePlus;EPSD	TCGA;ICGC;COSMIC	0.983	Down-regulation
TKL_STKR_STKR2_TGFBR2_ST	P36897	TGFBR1	P37173	TGFBR2	T185	D183Y	183	Missense	proximal	-2	no	1.780	1.745	PhosphoSitePlus;EPSD	TCGA;ICGC;COSMIC	0.983	Down-regulation
TKL_STKR_STKR2_TGFBR2_ST	P36897	TGFBR1	P37173	TGFBR2	T186	T186M	186	Missense	central	0	yes	1.939	0.000	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	0.983	Loss
TKL_STKR_STKR2_TGFBR2_ST	P36897	TGFBR1	P37173	TGFBR2	T186	D183Y	183	Missense	distal	-3	no	1.939	1.976	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	0.983	Up-regulation
TKL_STKR_STKR2_TGFBR2_ST	P36897	TGFBR1	P37173	TGFBR2	S187	T186M	186	Missense	proximal	-1	no	2.011	1.990	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	0.983	Down-regulation
TKL_STKR_STKR2_TGFBR2_ST	P36897	TGFBR1	P37173	TGFBR2	S187	D183Y	183	Missense	distal	-4	no	2.011	2.043	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	0.983	Up-regulation
TKL_STKR_STKR2_TGFBR2_ST	P36897	TGFBR1	P37173	TGFBR2	S187	P194S	194	Missense	distal	7	no	2.011	2.022	EPSD;PhosphoSitePlus	TCGA;COSMIC	0.983	Up-regulation
TKL_STKR_STKR2_TGFBR2_ST	P36897	TGFBR1	P37173	TGFBR2	S189	T186M	186	Missense	distal	-3	no	1.713	1.805	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	0.983	Up-regulation
TKL_STKR_STKR2_TGFBR2_ST	P36897	TGFBR1	P37173	TGFBR2	S189	D183Y	183	Missense	distal	-6	no	1.713	1.681	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	0.983	Down-regulation
TKL_STKR_STKR2_TGFBR2_ST	P36897	TGFBR1	P37173	TGFBR2	S189	P194S	194	Missense	distal	5	no	1.713	1.709	EPSD;PhosphoSitePlus	TCGA;COSMIC	0.983	Down-regulation
TKL_STKR_STKR2_TGFBR2_ST	P36897	TGFBR1	P37173	TGFBR2	S191	T186M	186	Missense	distal	-5	no	1.909	1.860	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	0.983	Down-regulation
TKL_STKR_STKR2_TGFBR2_ST	P36897	TGFBR1	P37173	TGFBR2	S191	P194S	194	Missense	distal	3	no	1.909	1.851	EPSD;PhosphoSitePlus	TCGA;COSMIC	0.983	Down-regulation
TKL_STKR_STKR2_TGFBR2_ST	P36897	TGFBR1	P37173	TGFBR2	T296	T296I	296	Missense	central	0	yes	0.990	0.000	EPSD	TCGA;COSMIC	0.983	Loss
TKL_STKR_STKR2_TGFBR2_ST	O75604	USP2	P37173	TGFBR2	S58	R64S	64	Missense	distal	6	no	0.988	1.010	EPSD	TCGA;ICGC;COSMIC	0.983	Up-regulation
TKL_STKR_STKR2_TGFBR2_ST	O75604	USP2	P37173	TGFBR2	S58	T61A	61	Missense	distal	3	no	0.988	0.979	EPSD	TCGA;ICGC;COSMIC	0.983	Loss
TKL_STKR_STKR2_TGFBR2_ST	O75604	USP2	P37173	TGFBR2	S144	F150L	150	Missense	distal	6	no	0.875	0.984	EPSD	TCGA;ICGC;COSMIC	0.983	Gain
TKL_STKR_STKR2_TGFBR2_ST	O75604	USP2	P37173	TGFBR2	S169	T175M	175	Missense	distal	6	no	1.011	0.987	EPSD	TCGA;ICGC;GDSC	0.983	Down-regulation
TKL_STKR_STKR2_TGFBR2_ST	O75604	USP2	P37173	TGFBR2	S169	R168C	168	Missense	proximal	-1	no	1.011	1.032	EPSD	TCGA;ICGC;COSMIC	0.983	Up-regulation
TKL_STKR_STKR2_TGFBR2_ST	O75604	USP2	P37173	TGFBR2	S169	L166M	166	Missense	distal	-3	no	1.011	0.994	EPSD	TCGA;ICGC	0.983	Down-regulation
TKL_STKR_STKR2_TGFBR2_ST	O75604	USP2	P37173	TGFBR2	T175	T175M	175	Missense	central	0	yes	1.091	0.000	EPSD	TCGA;ICGC;GDSC	0.983	Loss
TKL_STKR_STKR2_TGFBR2_ST	O75604	USP2	P37173	TGFBR2	T175	R168C	168	Missense	distal	-7	no	1.091	1.096	EPSD	TCGA;ICGC;COSMIC	0.983	Up-regulation
TKL_STKR_STKR2_TGFBR2_ST	O75604	USP2	P37173	TGFBR2	S207	S209Y	209	Missense	proximal	2	no	1.937	1.745	PhosphoSitePlus;EPSD	TCGA;ICGC;COSMIC	0.983	Down-regulation
TKL_STKR_STKR2_TGFBR2_ST	O75604	USP2	P37173	TGFBR2	S207	Q214H	214	Missense	distal	7	no	1.937	1.940	PhosphoSitePlus;EPSD	TCGA;ICGC;COSMIC	0.983	Up-regulation
TKL_STKR_STKR2_TGFBR2_ST	O75604	USP2	P37173	TGFBR2	S207	R204H	204	Missense	distal	-3	no	1.937	1.900	PhosphoSitePlus;EPSD	TCGA;ICGC;COSMIC	0.983	Down-regulation
TKL_STKR_STKR2_TGFBR2_ST	O75604	USP2	P37173	TGFBR2	S225	R229Q	229	Missense	distal	4	no	1.792	1.785	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	0.983	Down-regulation
TKL_STKR_STKR2_TGFBR2_ST	O75604	USP2	P37173	TGFBR2	S225	P221S	221	Missense	distal	-4	no	1.792	1.655	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	0.983	Down-regulation
CMGC_CLK_CLK1_ST	P00519	ABL1	P49759	CLK1	T613	S620G	620	Missense	distal	7	no	57.730	53.781	EPSD	TCGA;COSMIC	52.547	Down-regulation
CMGC_CLK_CLK1_ST	P00519	ABL1	P49759	CLK1	T613	S620R	620	Missense	distal	7	no	57.730	57.854	EPSD	TCGA;COSMIC	52.547	Up-regulation
CMGC_CLK_CLK1_ST	P00519	ABL1	P49759	CLK1	S620	S620G	620	Missense	central	0	yes	68.910	0.000	EPSD	TCGA;COSMIC	52.547	Loss
CMGC_CLK_CLK1_ST	P00519	ABL1	P49759	CLK1	S620	S620R	620	Missense	central	0	yes	68.910	0.000	EPSD	TCGA;COSMIC	52.547	Loss
CMGC_CLK_CLK1_ST	Q96I25	RBM17	P49759	CLK1	S48	A52T	52	Missense	distal	4	no	95.061	94.970	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	52.547	Down-regulation
CMGC_CLK_CLK1_ST	Q96I25	RBM17	P49759	CLK1	S62	V69A	69	Missense	distal	7	no	98.929	98.423	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	52.547	Down-regulation
CMGC_CLK_CLK1_ST	Q96I25	RBM17	P49759	CLK1	T71	V69A	69	Missense	proximal	-2	no	48.557	53.953	EPSD	TCGA;ICGC;COSMIC	52.547	Gain
CMGC_CLK_CLK1_ST	Q96I25	RBM17	P49759	CLK1	S169	R163Q	163	Missense	distal	-6	no	64.032	63.228	EPSD	TCGA;ICGC;COSMIC	52.547	Down-regulation
CMGC_CLK_CLK1_ST	Q96I25	RBM17	P49759	CLK1	S169	G172E	172	Missense	distal	3	no	64.032	65.765	EPSD	TCGA;ICGC;COSMIC	52.547	Up-regulation
CMGC_CLK_CLK1_ST	Q96I25	RBM17	P49759	CLK1	S222	E215K	215	Missense	distal	-7	no	100.524	99.091	PhosphoSitePlus;EPSD	TCGA;ICGC;COSMIC	52.547	Down-regulation
CMGC_CLK_CLK1_ST	Q96I25	RBM17	P49759	CLK1	T224	F230L	230	Missense	distal	6	no	68.289	70.210	EPSD	TCGA;ICGC;COSMIC	52.547	Up-regulation
CMGC_CLK_CLK1_ST	Q96I25	RBM17	P49759	CLK1	S266	E268D	268	Missense	proximal	2	no	96.706	96.890	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	52.547	Up-regulation
CMGC_CLK_CLK1_ST	Q96I25	RBM17	P49759	CLK1	S266	R273C	273	Missense	distal	7	no	96.706	94.529	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	52.547	Down-regulation
CMGC_CLK_CLK1_ST	Q96I25	RBM17	P49759	CLK1	S266	A264V	264	Missense	proximal	-2	no	96.706	91.309	EPSD;PhosphoSitePlus	TCGA;ICGC	52.547	Down-regulation
CMGC_CLK_CLK1_ST	Q96I25	RBM17	P49759	CLK1	S288	P295A	295	Missense	distal	7	no	100.958	101.523	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	52.547	Up-regulation
CMGC_CLK_CLK1_ST	Q96I25	RBM17	P49759	CLK1	S288	D281N	281	Missense	distal	-7	no	100.958	93.918	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	52.547	Down-regulation
CMGC_CLK_CLK1_ST	Q96I25	RBM17	P49759	CLK1	S288	P295L	295	Missense	distal	7	no	100.958	99.311	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	52.547	Down-regulation
CMGC_CLK_CLK1_ST	Q96I25	RBM17	P49759	CLK1	S288	E284G	284	Missense	distal	-4	no	100.958	101.049	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	52.547	Up-regulation
CMGC_CLK_CLK1_ST	Q96I25	RBM17	P49759	CLK1	S291	P295A	295	Missense	distal	4	no	94.005	94.792	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	52.547	Up-regulation
CMGC_CLK_CLK1_ST	Q96I25	RBM17	P49759	CLK1	S291	P295L	295	Missense	distal	4	no	94.005	94.940	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	52.547	Up-regulation
CMGC_CLK_CLK1_ST	Q96I25	RBM17	P49759	CLK1	S291	T297S	297	Missense	distal	6	no	94.005	95.167	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	52.547	Up-regulation
CMGC_CLK_CLK1_ST	Q96I25	RBM17	P49759	CLK1	S291	E284G	284	Missense	distal	-7	no	94.005	92.207	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	52.547	Down-regulation
CMGC_CLK_CLK1_ST	Q96I25	RBM17	P49759	CLK1	S293	P295A	295	Missense	proximal	2	no	56.282	56.481	EPSD	TCGA;ICGC;COSMIC	52.547	Up-regulation
CMGC_CLK_CLK1_ST	Q96I25	RBM17	P49759	CLK1	S293	P295L	295	Missense	proximal	2	no	56.282	56.109	EPSD	TCGA;ICGC;COSMIC	52.547	Down-regulation
CMGC_CLK_CLK1_ST	Q96I25	RBM17	P49759	CLK1	S293	T297S	297	Missense	distal	4	no	56.282	54.747	EPSD	TCGA;ICGC;COSMIC	52.547	Down-regulation
CMGC_CLK_CLK1_ST	P18031	PTPN1	P49759	CLK1	S50	D53H	53	Missense	distal	3	no	105.509	103.025	EPSD;PhosphoSitePlus	TCGA;COSMIC	52.547	Down-regulation
CMGC_CLK_CLK1_ST	P18031	PTPN1	P49759	CLK1	S50	Y46H	46	Missense	distal	-4	no	105.509	105.448	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	52.547	Down-regulation
CMGC_CLK_CLK1_ST	P18031	PTPN1	P49759	CLK1	S50	D48Y	48	Missense	proximal	-2	no	105.509	98.741	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	52.547	Down-regulation
CMGC_CLK_CLK1_ST	P18031	PTPN1	P49759	CLK1	S50	P51L	51	Missense	proximal	1	no	105.509	105.802	EPSD;PhosphoSitePlus	TCGA;ICGC	52.547	Up-regulation
CMGC_CLK_CLK1_ST	P18031	PTPN1	P49759	CLK1	S50	R43Q	43	Missense	distal	-7	no	105.509	104.621	EPSD;PhosphoSitePlus	TCGA;ICGC	52.547	Down-regulation
CMGC_CLK_CLK1_ST	P18031	PTPN1	P49759	CLK1	S222	A217T	217	Missense	distal	-5	no	45.440	53.788	EPSD	TCGA;COSMIC	52.547	Gain
CMGC_CLK_CLK1_ST	P18031	PTPN1	P49759	CLK1	S222	G220S	220	Missense	proximal	-2	no	45.440	53.742	EPSD	TCGA	52.547	Gain
CMGC_CLK_CLK1_ST	P18031	PTPN1	P49759	CLK1	S222	I219T	219	Missense	distal	-3	no	45.440	53.674	EPSD	TCGA;COSMIC	52.547	Gain
CMGC_CLK_CLK1_ST	P18031	PTPN1	P49759	CLK1	S242	V244I	244	Missense	proximal	2	no	93.842	94.008	EPSD;PhosphoSitePlus	TCGA;COSMIC	52.547	Up-regulation
CMGC_CLK_CLK1_ST	P18031	PTPN1	P49759	CLK1	S243	V244I	244	Missense	proximal	1	no	103.093	103.172	PhosphoSitePlus;EPSD	TCGA;COSMIC	52.547	Up-regulation
CMGC_CLK_CLK1_ST	P18031	PTPN1	P49759	CLK1	S295	S295F	295	Missense	central	0	yes	61.298	0.000	EPSD	TCGA;COSMIC	52.547	Loss
CAMK_CAMKL_BRSK_BRSK2_ST	P49815	TSC2	Q8IWQ3	BRSK2	S946	R943K	943	Missense	distal	-3	no	4.455	4.500	EPSD	TCGA;ICGC;COSMIC	3.184	Up-regulation
CAMK_CAMKL_BRSK_BRSK2_ST	P49815	TSC2	Q8IWQ3	BRSK2	S997	D1004N	1004	Missense	distal	7	no	4.377	4.316	EPSD	TCGA;COSMIC	3.184	Down-regulation
CAMK_CAMKL_BRSK_BRSK2_ST	P49815	TSC2	Q8IWQ3	BRSK2	S997	G1001V	1001	Missense	distal	4	no	4.377	4.524	EPSD	TCGA;COSMIC	3.184	Up-regulation
CAMK_CAMKL_BRSK_BRSK2_ST	P49815	TSC2	Q8IWQ3	BRSK2	S1002	G1001V	1001	Missense	proximal	-1	no	4.017	4.038	EPSD	TCGA;COSMIC	3.184	Up-regulation
CAMK_CAMKL_BRSK_BRSK2_ST	P49815	TSC2	Q8IWQ3	BRSK2	S1095	G1091S	1091	Missense	distal	-4	no	2.731	3.353	EPSD	TCGA;COSMIC	3.184	Gain
CAMK_CAMKL_BRSK_BRSK2_ST	P49815	TSC2	Q8IWQ3	BRSK2	S1097	P1098L	1098	Missense	proximal	1	no	3.312	3.794	EPSD	TCGA;COSMIC	3.184	Up-regulation
CAMK_CAMKL_BRSK_BRSK2_ST	P49815	TSC2	Q8IWQ3	BRSK2	S1097	G1091S	1091	Missense	distal	-6	no	3.312	3.274	EPSD	TCGA;COSMIC	3.184	Down-regulation
CAMK_CAMKL_BRSK_BRSK2_ST	P49815	TSC2	Q8IWQ3	BRSK2	S1338	E1343D	1343	Missense	distal	5	no	4.897	5.002	EPSD	TCGA	3.184	Up-regulation
CAMK_CAMKL_BRSK_BRSK2_ST	P49815	TSC2	Q8IWQ3	BRSK2	S1338	S1341N	1341	Missense	distal	3	no	4.897	5.141	EPSD	TCGA;COSMIC	3.184	Up-regulation
CAMK_CAMKL_BRSK_BRSK2_ST	P49815	TSC2	Q8IWQ3	BRSK2	S1341	H1348Q	1348	Missense	distal	7	no	4.517	4.536	EPSD	TCGA;COSMIC	3.184	Up-regulation
CAMK_CAMKL_BRSK_BRSK2_ST	P49815	TSC2	Q8IWQ3	BRSK2	S1341	E1343D	1343	Missense	proximal	2	no	4.517	4.515	EPSD	TCGA	3.184	Down-regulation
CAMK_CAMKL_BRSK_BRSK2_ST	P49815	TSC2	Q8IWQ3	BRSK2	S1341	S1341N	1341	Missense	central	0	yes	4.517	0.000	EPSD	TCGA;COSMIC	3.184	Loss
CAMK_CAMKL_BRSK_BRSK2_ST	P49815	TSC2	Q8IWQ3	BRSK2	S1379	S1386I	1386	Missense	distal	7	no	3.716	3.729	EPSD	TCGA;COSMIC	3.184	Up-regulation
CAMK_CAMKL_BRSK_BRSK2_ST	P49815	TSC2	Q8IWQ3	BRSK2	S1383	S1386I	1386	Missense	distal	3	no	3.458	3.739	EPSD	TCGA;COSMIC	3.184	Up-regulation
CAMK_CAMKL_BRSK_BRSK2_ST	P49815	TSC2	Q8IWQ3	BRSK2	S1387	S1386I	1386	Missense	proximal	-1	no	9.939	9.772	PhosphoSitePlus	TCGA;COSMIC	3.184	Down-regulation
CAMK_CAMKL_BRSK_BRSK2_ST	P49815	TSC2	Q8IWQ3	BRSK2	T1462	S1466L	1466	Missense	distal	4	no	3.574	3.830	EPSD	TCGA	3.184	Up-regulation
CAMK_CAMKL_BRSK_BRSK2_ST	P49815	TSC2	Q8IWQ3	BRSK2	T1462	R1457Q	1457	Missense	distal	-5	no	3.574	3.598	EPSD	TCGA;COSMIC	3.184	Up-regulation
CAMK_CAMKL_BRSK_BRSK2_ST	P49815	TSC2	Q8IWQ3	BRSK2	S1730	S1730P	1730	Missense	central	0	yes	4.765	0.000	EPSD	TCGA;COSMIC	3.184	Loss
CAMK_CAMKL_BRSK_BRSK2_ST	P49815	TSC2	Q8IWQ3	BRSK2	S1730	D1734N	1734	Missense	distal	4	no	4.765	4.943	EPSD	TCGA	3.184	Up-regulation
Atypical_PIKK_DNAPK_PRKDC_ST	P78527	PRKDC	P78527	PRKDC	S314	L308V	308	Missense	distal	-6	no	8.296	7.829	EPSD	TCGA;ICGC;COSMIC	8.283	Loss
Atypical_PIKK_DNAPK_PRKDC_ST	P78527	PRKDC	P78527	PRKDC	S314	L320V	320	Missense	distal	6	no	8.296	8.285	EPSD	TCGA;ICGC;COSMIC	8.283	Down-regulation
Atypical_PIKK_DNAPK_PRKDC_ST	P78527	PRKDC	P78527	PRKDC	S314	L313F	313	Missense	proximal	-1	no	8.296	8.522	EPSD	TCGA;ICGC;COSMIC	8.283	Up-regulation
Atypical_PIKK_DNAPK_PRKDC_ST	P78527	PRKDC	P78527	PRKDC	S842	E844K	844	Missense	proximal	2	no	8.604	6.628	EPSD	TCGA;ICGC;COSMIC;CCLE	8.283	Loss
Atypical_PIKK_DNAPK_PRKDC_ST	P78527	PRKDC	P78527	PRKDC	S842	K838N	838	Missense	distal	-4	no	8.604	8.880	EPSD	TCGA;ICGC;COSMIC;CCLE	8.283	Up-regulation
Atypical_PIKK_DNAPK_PRKDC_ST	P78527	PRKDC	P78527	PRKDC	S882	S875F	875	Missense	distal	-7	no	8.862	8.317	EPSD	TCGA;ICGC;COSMIC	8.283	Down-regulation
Atypical_PIKK_DNAPK_PRKDC_ST	P78527	PRKDC	P78527	PRKDC	S1058	K1057N	1057	Missense	proximal	-1	no	7.972	8.571	EPSD	TCGA;ICGC;COSMIC	8.283	Gain
Atypical_PIKK_DNAPK_PRKDC_ST	P78527	PRKDC	P78527	PRKDC	S2677	S2674F	2674	Missense	distal	-3	no	8.891	8.874	EPSD	TCGA;ICGC	8.283	Down-regulation
Atypical_PIKK_DNAPK_PRKDC_ST	P78527	PRKDC	P78527	PRKDC	S3821	L3815P	3815	Missense	distal	-6	no	11.993	11.874	EPSD	TCGA;ICGC	8.283	Down-regulation
Atypical_PIKK_DNAPK_PRKDC_ST	P14859	POU2F1	P78527	PRKDC	S88	Q94H	94	Missense	distal	6	no	14.542	14.532	EPSD;PhosphoSitePlus	TCGA;COSMIC	8.283	Down-regulation
Atypical_PIKK_DNAPK_PRKDC_ST	P14859	POU2F1	P78527	PRKDC	S88	V93A	93	Missense	distal	5	no	14.542	14.720	EPSD;PhosphoSitePlus	TCGA;COSMIC	8.283	Up-regulation
Atypical_PIKK_DNAPK_PRKDC_ST	P14859	POU2F1	P78527	PRKDC	S92	Q94H	94	Missense	proximal	2	no	9.504	9.048	PhosphoSitePlus;EPSD	TCGA;COSMIC	8.283	Down-regulation
Atypical_PIKK_DNAPK_PRKDC_ST	P14859	POU2F1	P78527	PRKDC	S92	V93A	93	Missense	proximal	1	no	9.504	10.240	PhosphoSitePlus;EPSD	TCGA;COSMIC	8.283	Up-regulation
Atypical_PIKK_DNAPK_PRKDC_ST	P14859	POU2F1	P78527	PRKDC	T100	Q94H	94	Missense	distal	-6	no	12.846	12.597	EPSD;PhosphoSitePlus	TCGA;COSMIC	8.283	Down-regulation
Atypical_PIKK_DNAPK_PRKDC_ST	P14859	POU2F1	P78527	PRKDC	T100	V93A	93	Missense	distal	-7	no	12.846	13.768	EPSD;PhosphoSitePlus	TCGA;COSMIC	8.283	Up-regulation
Atypical_PIKK_DNAPK_PRKDC_ST	P14859	POU2F1	P78527	PRKDC	S361	L368H	368	Missense	distal	7	no	9.604	10.383	EPSD	TCGA;COSMIC	8.283	Up-regulation
Atypical_PIKK_DNAPK_PRKDC_ST	P14859	POU2F1	P78527	PRKDC	S364	L368H	368	Missense	distal	4	no	9.327	9.330	EPSD	TCGA;COSMIC	8.283	Up-regulation
Atypical_PIKK_DNAPK_PRKDC_ST	P14859	POU2F1	P78527	PRKDC	S370	L368H	368	Missense	proximal	-2	no	9.575	9.547	EPSD	TCGA;COSMIC	8.283	Down-regulation
Atypical_PIKK_DNAPK_PRKDC_ST	P35637	FUS	P78527	PRKDC	S26	S29N	29	Missense	distal	3	no	16.572	16.614	EPSD;PhosphoSitePlus	TCGA;ICGC	8.283	Up-regulation
Atypical_PIKK_DNAPK_PRKDC_ST	P35637	FUS	P78527	PRKDC	S30	S29N	29	Missense	proximal	-1	no	12.400	12.409	EPSD;PhosphoSitePlus	TCGA;ICGC	8.283	Up-regulation
Atypical_PIKK_DNAPK_PRKDC_ST	P35637	FUS	P78527	PRKDC	S42	D46H	46	Missense	distal	4	no	13.722	13.709	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	8.283	Down-regulation
Atypical_PIKK_DNAPK_PRKDC_ST	P35637	FUS	P78527	PRKDC	S54	S53I	53	Missense	proximal	-1	no	11.624	10.257	EPSD;PhosphoSitePlus	TCGA;ICGC	8.283	Down-regulation
Atypical_PIKK_DNAPK_PRKDC_ST	P35637	FUS	P78527	PRKDC	S54	S53N	53	Missense	proximal	-1	no	11.624	11.632	EPSD;PhosphoSitePlus	TCGA;ICGC	8.283	Up-regulation
Atypical_PIKK_DNAPK_PRKDC_ST	P35637	FUS	P78527	PRKDC	S54	Y50C	50	Missense	distal	-4	no	11.624	11.127	EPSD;PhosphoSitePlus	TCGA	8.283	Down-regulation
Atypical_PIKK_DNAPK_PRKDC_ST	P35637	FUS	P78527	PRKDC	S112	S108N	108	Missense	distal	-4	no	9.169	9.147	EPSD;PhosphoSitePlus	TCGA;COSMIC	8.283	Down-regulation
Atypical_PIKK_DNAPK_PRKDC_ST	P35637	FUS	P78527	PRKDC	S131	Y136C	136	Missense	distal	5	no	14.280	14.121	EPSD;PhosphoSitePlus	TCGA;COSMIC	8.283	Down-regulation
Atypical_PIKK_DNAPK_PRKDC_ST	P35637	FUS	P78527	PRKDC	S142	Y136C	136	Missense	distal	-6	no	10.787	10.324	EPSD;PhosphoSitePlus	TCGA;COSMIC	8.283	Down-regulation
Atypical_PIKK_DNAPK_PRKDC_ST	P12956	XRCC6	P78527	PRKDC	S6	E11Q	11	Missense	distal	5	no	10.268	10.279	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	8.283	Up-regulation
Atypical_PIKK_DNAPK_PRKDC_ST	P12956	XRCC6	P78527	PRKDC	T10	E11Q	11	Missense	proximal	1	no	6.355	14.090	EPSD	TCGA;ICGC;COSMIC	8.283	Gain
Atypical_PIKK_DNAPK_PRKDC_ST	P12956	XRCC6	P78527	PRKDC	S51	E54K	54	Missense	distal	3	no	15.081	14.523	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	8.283	Down-regulation
Atypical_PIKK_DNAPK_PRKDC_ST	P12956	XRCC6	P78527	PRKDC	S51	M48I	48	Missense	distal	-3	no	15.081	14.842	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	8.283	Down-regulation
Atypical_PIKK_DNAPK_PRKDC_ST	P12956	XRCC6	P78527	PRKDC	T58	E54K	54	Missense	distal	-4	no	10.382	10.125	EPSD	TCGA;ICGC;COSMIC	8.283	Down-regulation
Atypical_PIKK_DNAPK_PRKDC_ST	Q96SD1	DCLRE1C	P78527	PRKDC	T251	R249C	249	Missense	proximal	-2	no	8.371	8.400	EPSD	TCGA;COSMIC	8.283	Up-regulation
Atypical_PIKK_DNAPK_PRKDC_ST	Q96SD1	DCLRE1C	P78527	PRKDC	T251	C256F	256	Missense	distal	5	no	8.371	8.526	EPSD	TCGA;COSMIC	8.283	Up-regulation
Atypical_PIKK_DNAPK_PRKDC_ST	Q96SD1	DCLRE1C	P78527	PRKDC	T251	Q252H	252	Missense	proximal	1	no	8.371	-1.964	EPSD	TCGA;COSMIC	8.283	Loss
Atypical_PIKK_DNAPK_PRKDC_ST	Q96SD1	DCLRE1C	P78527	PRKDC	T251	R249H	249	Missense	proximal	-2	no	8.371	8.240	EPSD	TCGA;COSMIC	8.283	Loss
Atypical_PIKK_DNAPK_PRKDC_ST	Q96SD1	DCLRE1C	P78527	PRKDC	T251	R257Q	257	Missense	distal	6	no	8.371	8.407	EPSD	TCGA;COSMIC	8.283	Up-regulation
Atypical_PIKK_DNAPK_PRKDC_ST	Q96SD1	DCLRE1C	P78527	PRKDC	S503	N496S	496	Missense	distal	-7	no	10.546	10.862	PhosphoSitePlus;EPSD	TCGA	8.283	Up-regulation
Atypical_PIKK_DNAPK_PRKDC_ST	Q96SD1	DCLRE1C	P78527	PRKDC	S503	S509F	509	Missense	distal	6	no	10.546	10.549	PhosphoSitePlus;EPSD	TCGA;COSMIC	8.283	Up-regulation
Atypical_PIKK_DNAPK_PRKDC_ST	Q96SD1	DCLRE1C	P78527	PRKDC	S510	T511P	511	Missense	proximal	1	no	3.778	9.842	EPSD	TCGA	8.283	Gain
Atypical_PIKK_DNAPK_PRKDC_ST	Q96SD1	DCLRE1C	P78527	PRKDC	S516	T511K	511	Missense	distal	-5	no	12.866	13.074	EPSD;PhosphoSitePlus	TCGA	8.283	Up-regulation
Atypical_PIKK_DNAPK_PRKDC_ST	Q96SD1	DCLRE1C	P78527	PRKDC	S516	T511P	511	Missense	distal	-5	no	12.866	12.736	EPSD;PhosphoSitePlus	TCGA	8.283	Down-regulation
Atypical_PIKK_DNAPK_PRKDC_ST	Q96SD1	DCLRE1C	P78527	PRKDC	S516	S509F	509	Missense	distal	-7	no	12.866	12.321	EPSD;PhosphoSitePlus	TCGA;COSMIC	8.283	Down-regulation
Atypical_PIKK_DNAPK_PRKDC_ST	Q96SD1	DCLRE1C	P78527	PRKDC	S516	L521F	521	Missense	distal	5	no	12.866	12.897	EPSD;PhosphoSitePlus	TCGA;COSMIC	8.283	Up-regulation
Atypical_PIKK_DNAPK_PRKDC_ST	Q96SD1	DCLRE1C	P78527	PRKDC	S518	T511K	511	Missense	distal	-7	no	9.168	9.279	EPSD	TCGA	8.283	Up-regulation
Atypical_PIKK_DNAPK_PRKDC_ST	Q96SD1	DCLRE1C	P78527	PRKDC	S518	T511P	511	Missense	distal	-7	no	9.168	8.837	EPSD	TCGA	8.283	Down-regulation
Atypical_PIKK_DNAPK_PRKDC_ST	Q96SD1	DCLRE1C	P78527	PRKDC	S518	L521F	521	Missense	distal	3	no	9.168	9.264	EPSD	TCGA;COSMIC	8.283	Up-regulation
Atypical_PIKK_DNAPK_PRKDC_ST	Q96SD1	DCLRE1C	P78527	PRKDC	S534	T530I	530	Missense	distal	-4	no	11.868	11.250	EPSD;PhosphoSitePlus	TCGA;COSMIC	8.283	Down-regulation
Atypical_PIKK_DNAPK_PRKDC_ST	Q96SD1	DCLRE1C	P78527	PRKDC	S534	S537F	537	Missense	distal	3	no	11.868	11.582	EPSD;PhosphoSitePlus	TCGA;COSMIC	8.283	Down-regulation
Atypical_PIKK_DNAPK_PRKDC_ST	Q96SD1	DCLRE1C	P78527	PRKDC	S538	S537F	537	Missense	proximal	-1	no	13.949	14.213	EPSD;PhosphoSitePlus	TCGA;COSMIC	8.283	Up-regulation
Atypical_PIKK_DNAPK_PRKDC_ST	Q96SD1	DCLRE1C	P78527	PRKDC	S548	S548N	548	Missense	central	0	yes	10.820	0.000	EPSD;PhosphoSitePlus	TCGA;COSMIC	8.283	Loss
Atypical_PIKK_DNAPK_PRKDC_ST	Q96SD1	DCLRE1C	P78527	PRKDC	S553	S548N	548	Missense	distal	-5	no	18.059	17.905	EPSD;PhosphoSitePlus	TCGA;COSMIC	8.283	Down-regulation
Atypical_PIKK_DNAPK_PRKDC_ST	Q96SD1	DCLRE1C	P78527	PRKDC	S553	S548T	548	Missense	distal	-5	no	18.059	17.818	EPSD;PhosphoSitePlus	TCGA;COSMIC	8.283	Down-regulation
Atypical_PIKK_DNAPK_PRKDC_ST	Q96SD1	DCLRE1C	P78527	PRKDC	S553	D556N	556	Missense	distal	3	no	18.059	18.065	EPSD;PhosphoSitePlus	TCGA;COSMIC	8.283	Up-regulation
Atypical_PIKK_DNAPK_PRKDC_ST	Q96SD1	DCLRE1C	P78527	PRKDC	S553	D556G	556	Missense	distal	3	no	18.059	17.763	EPSD;PhosphoSitePlus	TCGA;COSMIC	8.283	Down-regulation
Atypical_PIKK_DNAPK_PRKDC_ST	Q96SD1	DCLRE1C	P78527	PRKDC	S562	D556N	556	Missense	distal	-6	no	13.528	13.584	EPSD	TCGA;COSMIC	8.283	Up-regulation
Atypical_PIKK_DNAPK_PRKDC_ST	Q96SD1	DCLRE1C	P78527	PRKDC	S562	D556G	556	Missense	distal	-6	no	13.528	13.343	EPSD	TCGA;COSMIC	8.283	Down-regulation
Atypical_PIKK_DNAPK_PRKDC_ST	Q96SD1	DCLRE1C	P78527	PRKDC	S645	N638T	638	Missense	distal	-7	no	12.975	12.972	EPSD;PhosphoSitePlus	TCGA;COSMIC	8.283	Down-regulation
Atypical_PIKK_DNAPK_PRKDC_ST	P23508	MCC	P78527	PRKDC	T803	R800K	800	Missense	distal	-3	no	9.897	10.050	EPSD	TCGA	8.283	Up-regulation
Atypical_PIKK_DNAPK_PRKDC_ST	P23508	MCC	P78527	PRKDC	T803	L808F	808	Missense	distal	5	no	9.897	9.929	EPSD	TCGA;COSMIC	8.283	Up-regulation
Atypical_PIKK_DNAPK_PRKDC_ST	P23508	MCC	P78527	PRKDC	T803	L808I	808	Missense	distal	5	no	9.897	9.632	EPSD	TCGA;COSMIC	8.283	Down-regulation
Atypical_PIKK_DNAPK_PRKDC_ST	Q14653	IRF3	P78527	PRKDC	S123	D116Y	116	Missense	distal	-7	no	8.768	8.507	EPSD	TCGA;ICGC;COSMIC	8.283	Down-regulation
Atypical_PIKK_DNAPK_PRKDC_ST	Q14653	IRF3	P78527	PRKDC	S123	G129E	129	Missense	distal	6	no	8.768	8.800	EPSD	TCGA;COSMIC	8.283	Up-regulation
Atypical_PIKK_DNAPK_PRKDC_ST	Q14653	IRF3	P78527	PRKDC	T135	D138G	138	Missense	distal	3	no	14.457	14.162	PhosphoSitePlus	TCGA;COSMIC	8.283	Down-regulation
Atypical_PIKK_DNAPK_PRKDC_ST	Q14653	IRF3	P78527	PRKDC	T135	G129E	129	Missense	distal	-6	no	14.457	14.792	PhosphoSitePlus	TCGA;COSMIC	8.283	Up-regulation
Atypical_PIKK_DNAPK_PRKDC_ST	Q14653	IRF3	P78527	PRKDC	S175	P170S	170	Missense	distal	-5	no	8.843	9.214	EPSD	TCGA;COSMIC;CCLE	8.283	Up-regulation
Atypical_PIKK_DNAPK_PRKDC_ST	Q13426	XRCC4	P78527	PRKDC	S219	E220Q	220	Missense	proximal	1	no	4.675	12.410	EPSD	TCGA;ICGC;COSMIC	8.283	Gain
Atypical_PIKK_DNAPK_PRKDC_ST	Q13426	XRCC4	P78527	PRKDC	S260	D265N	265	Missense	distal	5	no	10.057	9.907	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	8.283	Down-regulation
Atypical_PIKK_DNAPK_PRKDC_ST	Q13426	XRCC4	P78527	PRKDC	S260	L261I	261	Missense	proximal	1	no	10.057	1.643	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	8.283	Loss
Atypical_PIKK_DNAPK_PRKDC_ST	Q13426	XRCC4	P78527	PRKDC	S304	T308M	308	Missense	distal	4	no	8.990	9.001	EPSD;PhosphoSitePlus	TCGA;COSMIC	8.283	Up-regulation
Atypical_PIKK_DNAPK_PRKDC_ST	Q13426	XRCC4	P78527	PRKDC	S304	S303Y	303	Missense	proximal	-1	no	8.990	9.327	EPSD;PhosphoSitePlus	TCGA;COSMIC	8.283	Up-regulation
Atypical_PIKK_DNAPK_PRKDC_ST	Q13426	XRCC4	P78527	PRKDC	S304	R300M	300	Missense	distal	-4	no	8.990	8.860	EPSD;PhosphoSitePlus	TCGA;COSMIC	8.283	Down-regulation
Atypical_PIKK_DNAPK_PRKDC_ST	Q13426	XRCC4	P78527	PRKDC	S315	E317K	317	Missense	proximal	2	no	8.514	6.537	EPSD	TCGA;COSMIC	8.283	Loss
Atypical_PIKK_DNAPK_PRKDC_ST	Q13426	XRCC4	P78527	PRKDC	S315	T308M	308	Missense	distal	-7	no	8.514	8.188	EPSD	TCGA;COSMIC	8.283	Loss
Atypical_PIKK_DNAPK_PRKDC_ST	Q13426	XRCC4	P78527	PRKDC	S320	E317K	317	Missense	distal	-3	no	9.726	9.504	EPSD;PhosphoSitePlus	TCGA;COSMIC	8.283	Down-regulation
Atypical_PIKK_DNAPK_PRKDC_ST	Q13426	XRCC4	P78527	PRKDC	T323	E317K	317	Missense	distal	-6	no	10.815	10.606	EPSD	TCGA;COSMIC	8.283	Down-regulation
Atypical_PIKK_DNAPK_PRKDC_ST	Q14191	WRN	P78527	PRKDC	S319	L318F	318	Missense	proximal	-1	no	10.152	10.378	PhosphoSitePlus;EPSD	TCGA;ICGC;COSMIC	8.283	Up-regulation
Atypical_PIKK_DNAPK_PRKDC_ST	Q14191	WRN	P78527	PRKDC	S319	S323L	323	Missense	distal	4	no	10.152	10.133	PhosphoSitePlus;EPSD	TCGA;ICGC;COSMIC	8.283	Down-regulation
Atypical_PIKK_DNAPK_PRKDC_ST	Q14191	WRN	P78527	PRKDC	S409	L405V	405	Missense	distal	-4	no	14.826	14.445	EPSD	TCGA;ICGC;COSMIC	8.283	Down-regulation
Atypical_PIKK_DNAPK_PRKDC_ST	Q14191	WRN	P78527	PRKDC	S426	E431K	431	Missense	distal	5	no	8.927	8.695	EPSD	TCGA;ICGC;COSMIC	8.283	Down-regulation
Atypical_PIKK_DNAPK_PRKDC_ST	Q14191	WRN	P78527	PRKDC	S426	T422S	422	Missense	distal	-4	no	8.927	9.573	EPSD	TCGA;ICGC;COSMIC	8.283	Up-regulation
Atypical_PIKK_DNAPK_PRKDC_ST	Q14191	WRN	P78527	PRKDC	S426	P427S	427	Missense	proximal	1	no	8.927	4.572	EPSD	TCGA;ICGC;COSMIC	8.283	Loss
Atypical_PIKK_DNAPK_PRKDC_ST	Q14191	WRN	P78527	PRKDC	S426	N430Y	430	Missense	distal	4	no	8.927	8.914	EPSD	TCGA;ICGC	8.283	Down-regulation
Atypical_PIKK_DNAPK_PRKDC_ST	Q14191	WRN	P78527	PRKDC	S440	Y436C	436	Missense	distal	-4	no	10.299	9.803	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	8.283	Down-regulation
Atypical_PIKK_DNAPK_PRKDC_ST	Q14191	WRN	P78527	PRKDC	S462	D468E	468	Missense	distal	6	no	9.037	9.050	EPSD	TCGA;ICGC;COSMIC	8.283	Up-regulation
Atypical_PIKK_DNAPK_PRKDC_ST	Q14191	WRN	P78527	PRKDC	S467	D468E	468	Missense	proximal	1	no	9.488	8.209	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	8.283	Loss
Atypical_PIKK_DNAPK_PRKDC_ST	Q14191	WRN	P78527	PRKDC	S1002	T1006P	1006	Missense	distal	4	no	9.018	9.034	EPSD	TCGA;ICGC;COSMIC	8.283	Up-regulation
Atypical_PIKK_DNAPK_PRKDC_ST	Q14191	WRN	P78527	PRKDC	S1058	L1063F	1063	Missense	distal	5	no	12.557	12.588	EPSD	TCGA;ICGC;COSMIC	8.283	Up-regulation
Atypical_PIKK_DNAPK_PRKDC_ST	Q14191	WRN	P78527	PRKDC	S1133	S1140P	1140	Missense	distal	7	no	11.445	11.318	EPSD	TCGA;ICGC;COSMIC	8.283	Down-regulation
Atypical_PIKK_DNAPK_PRKDC_ST	Q14191	WRN	P78527	PRKDC	S1139	S1140P	1140	Missense	proximal	1	no	6.418	10.773	EPSD	TCGA;ICGC;COSMIC	8.283	Gain
Atypical_PIKK_DNAPK_PRKDC_ST	Q14191	WRN	P78527	PRKDC	S1141	S1140P	1140	Missense	proximal	-1	no	15.405	15.744	EPSD	TCGA;ICGC;COSMIC	8.283	Up-regulation
Atypical_PIKK_DNAPK_PRKDC_ST	Q14191	WRN	P78527	PRKDC	S1292	S1292F	1292	Missense	central	0	yes	10.811	0.000	EPSD	TCGA;ICGC;COSMIC	8.283	Loss
Atypical_PIKK_DNAPK_PRKDC_ST	Q14191	WRN	P78527	PRKDC	S1292	A1294V	1294	Missense	proximal	2	no	10.811	9.180	EPSD	TCGA;ICGC;COSMIC	8.283	Down-regulation
Atypical_PIKK_DNAPK_PRKDC_ST	P04637	TP53	P78527	PRKDC	S9	P4L	4	Missense	distal	-5	no	12.301	12.314	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	8.283	Up-regulation
Atypical_PIKK_DNAPK_PRKDC_ST	P04637	TP53	P78527	PRKDC	S20	P27S	27	Missense	distal	7	no	8.830	8.957	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	8.283	Up-regulation
Atypical_PIKK_DNAPK_PRKDC_ST	P04637	TP53	P78527	PRKDC	S20	P27L	27	Missense	distal	7	no	8.830	8.202	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC;GDSC;CCLE	8.283	Loss
Atypical_PIKK_DNAPK_PRKDC_ST	P04637	TP53	P78527	PRKDC	S33	P27S	27	Missense	distal	-6	no	9.126	9.491	EPSD	TCGA;ICGC;COSMIC	8.283	Up-regulation
Atypical_PIKK_DNAPK_PRKDC_ST	P04637	TP53	P78527	PRKDC	S33	P27L	27	Missense	distal	-6	no	9.126	9.245	EPSD	TCGA;ICGC;COSMIC;GDSC;CCLE	8.283	Up-regulation
Atypical_PIKK_DNAPK_PRKDC_ST	P04637	TP53	P78527	PRKDC	S46	D48N	48	Missense	proximal	2	no	8.858	6.915	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC;GDSC;CCLE	8.283	Loss
Atypical_PIKK_DNAPK_PRKDC_ST	P04637	TP53	P78527	PRKDC	S99	G105C	105	Missense	distal	6	no	10.676	10.673	EPSD	TCGA;ICGC;COSMIC;GDSC	8.283	Down-regulation
Atypical_PIKK_DNAPK_PRKDC_ST	P04637	TP53	P78527	PRKDC	S99	S106R	106	Missense	distal	7	no	10.676	9.519	EPSD	TCGA;ICGC;COSMIC;GDSC;CCLE	8.283	Down-regulation
Atypical_PIKK_DNAPK_PRKDC_ST	P04637	TP53	P78527	PRKDC	S99	G105R	105	Missense	distal	6	no	10.676	10.666	EPSD	TCGA;ICGC;COSMIC;CCLE	8.283	Down-regulation
Atypical_PIKK_DNAPK_PRKDC_ST	P04637	TP53	P78527	PRKDC	S99	G105V	105	Missense	distal	6	no	10.676	10.672	EPSD	TCGA;ICGC;COSMIC	8.283	Down-regulation
Atypical_PIKK_DNAPK_PRKDC_ST	P04637	TP53	P78527	PRKDC	S99	G105D	105	Missense	distal	6	no	10.676	10.696	EPSD	TCGA;ICGC;COSMIC	8.283	Up-regulation
Atypical_PIKK_DNAPK_PRKDC_ST	P04637	TP53	P78527	PRKDC	S99	G105S	105	Missense	distal	6	no	10.676	10.685	EPSD	TCGA;ICGC;COSMIC	8.283	Up-regulation
Atypical_PIKK_DNAPK_PRKDC_ST	P04637	TP53	P78527	PRKDC	S99	V97D	97	Missense	proximal	-2	no	10.676	10.520	EPSD	TCGA;ICGC;COSMIC	8.283	Down-regulation
Atypical_PIKK_DNAPK_PRKDC_ST	P04637	TP53	P78527	PRKDC	S99	P92S	92	Missense	distal	-7	no	10.676	11.326	EPSD	TCGA;ICGC	8.283	Up-regulation
Atypical_PIKK_DNAPK_PRKDC_ST	P04637	TP53	P78527	PRKDC	T125	K132E	132	Missense	distal	7	no	7.932	8.745	EPSD	TCGA;ICGC;COSMIC;GDSC;CCLE	8.283	Gain
Atypical_PIKK_DNAPK_PRKDC_ST	P04637	TP53	P78527	PRKDC	T125	K132Q	132	Missense	distal	7	no	7.932	8.841	EPSD	TCGA;ICGC;COSMIC;GDSC;CCLE	8.283	Gain
Atypical_PIKK_DNAPK_PRKDC_ST	P04637	TP53	P78527	PRKDC	S183	C176S	176	Missense	distal	-7	no	7.239	8.399	EPSD	TCGA;ICGC;COSMIC;GDSC;CCLE	8.283	Gain
Atypical_PIKK_DNAPK_PRKDC_ST	P04637	TP53	P78527	PRKDC	S215	V216L	216	Missense	proximal	1	no	6.872	8.371	EPSD	TCGA;ICGC;COSMIC;GDSC;CCLE	8.283	Gain
Atypical_PIKK_DNAPK_PRKDC_ST	P04637	TP53	P78527	PRKDC	S269	F270V	270	Missense	proximal	1	no	7.664	8.482	EPSD	TCGA;ICGC;COSMIC	8.283	Gain
Atypical_PIKK_DNAPK_PRKDC_ST	P04637	TP53	P78527	PRKDC	S269	F270L	270	Missense	proximal	1	no	7.664	9.980	EPSD	TCGA;ICGC;COSMIC	8.283	Gain
Atypical_PIKK_DNAPK_PRKDC_ST	P04637	TP53	P78527	PRKDC	T284	E285Q	285	Missense	proximal	1	no	4.290	12.025	EPSD	TCGA;ICGC;COSMIC	8.283	Gain
Atypical_PIKK_DNAPK_PRKDC_ST	Q9UGP5	POLL	P78527	PRKDC	S43	R50H	50	Missense	distal	7	no	8.144	9.325	EPSD	TCGA;ICGC;COSMIC	8.283	Gain
Atypical_PIKK_DNAPK_PRKDC_ST	Q9UGP5	POLL	P78527	PRKDC	S167	A165T	165	Missense	proximal	-2	no	8.825	8.906	EPSD	TCGA;ICGC	8.283	Up-regulation
Atypical_PIKK_DNAPK_PRKDC_ST	Q9UGP5	POLL	P78527	PRKDC	S167	P168S	168	Missense	proximal	1	no	8.825	4.470	EPSD	TCGA;ICGC;COSMIC	8.283	Loss
Atypical_PIKK_DNAPK_PRKDC_ST	Q9UGP5	POLL	P78527	PRKDC	T398	E396Q	396	Missense	proximal	-2	no	9.494	9.415	EPSD	TCGA;ICGC;COSMIC	8.283	Down-regulation
Atypical_PIKK_DNAPK_PRKDC_ST	Q9UGP5	POLL	P78527	PRKDC	T398	A405V	405	Missense	distal	7	no	9.494	8.404	EPSD	TCGA;ICGC;COSMIC	8.283	Down-regulation
Atypical_PIKK_DNAPK_PRKDC_ST	Q9UGP5	POLL	P78527	PRKDC	S526	M525T	525	Missense	proximal	-1	no	9.461	9.831	EPSD	TCGA;ICGC;COSMIC	8.283	Up-regulation
Atypical_PIKK_DNAPK_PRKDC_ST	Q9UGP5	POLL	P78527	PRKDC	S526	A531V	531	Missense	distal	5	no	9.461	9.283	EPSD	TCGA;ICGC;COSMIC	8.283	Down-regulation
Atypical_PIKK_DNAPK_PRKDC_ST	Q9UGP5	POLL	P78527	PRKDC	S526	L532F	532	Missense	distal	6	no	9.461	9.465	EPSD	TCGA;ICGC	8.283	Up-regulation
Atypical_PIKK_DNAPK_PRKDC_ST	Q9UGP5	POLL	P78527	PRKDC	T553	G548S	548	Missense	distal	-5	no	7.989	8.291	EPSD	TCGA;ICGC;COSMIC	8.283	Gain
Atypical_PIKK_DNAPK_PRKDC_ST	P23025	XPA	P78527	PRKDC	S173	H172Y	172	Missense	proximal	-1	no	11.286	11.313	EPSD;PhosphoSitePlus	TCGA;ICGC	8.283	Up-regulation
Atypical_PIKK_DNAPK_PRKDC_ST	P23025	XPA	P78527	PRKDC	S196	S190F	190	Missense	distal	-6	no	13.509	13.017	PhosphoSitePlus;EPSD	TCGA;ICGC;COSMIC	8.283	Down-regulation
Atypical_PIKK_DNAPK_PRKDC_ST	P17936	IGFBP3	P78527	PRKDC	S231	N228K	228	Missense	distal	-3	no	9.047	8.769	EPSD	TCGA;COSMIC	8.283	Down-regulation
Atypical_PIKK_DNAPK_PRKDC_ST	P17936	IGFBP3	P78527	PRKDC	S231	V235M	235	Missense	distal	4	no	9.047	9.066	EPSD	TCGA;COSMIC	8.283	Up-regulation
Atypical_PIKK_DNAPK_PRKDC_ST	P17936	IGFBP3	P78527	PRKDC	S231	L227M	227	Missense	distal	-4	no	9.047	8.768	EPSD	TCGA;COSMIC	8.283	Down-regulation
Atypical_PIKK_DNAPK_PRKDC_ST	Q9H9Q4	NHEJ1	P78527	PRKDC	S55	K59N	59	Missense	distal	4	no	10.966	10.976	EPSD;PhosphoSitePlus	TCGA;ICGC	8.283	Up-regulation
Atypical_PIKK_DNAPK_PRKDC_ST	Q9H9Q4	NHEJ1	P78527	PRKDC	T223	Q230H	230	Missense	distal	7	no	11.838	11.748	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	8.283	Down-regulation
Atypical_PIKK_DNAPK_PRKDC_ST	Q9H9Q4	NHEJ1	P78527	PRKDC	T223	G229R	229	Missense	distal	6	no	11.838	11.827	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	8.283	Down-regulation
Atypical_PIKK_DNAPK_PRKDC_ST	Q9H9Q4	NHEJ1	P78527	PRKDC	S263	P265S	265	Missense	proximal	2	no	10.763	10.993	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	8.283	Up-regulation
Atypical_PIKK_DNAPK_PRKDC_ST	Q9H9Q4	NHEJ1	P78527	PRKDC	S263	P270H	270	Missense	distal	7	no	10.763	10.914	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	8.283	Up-regulation
Atypical_PIKK_DNAPK_PRKDC_ST	Q9H9Q4	NHEJ1	P78527	PRKDC	T266	P265S	265	Missense	proximal	-1	no	10.476	10.136	PhosphoSitePlus;EPSD	TCGA;ICGC;COSMIC	8.283	Down-regulation
Atypical_PIKK_DNAPK_PRKDC_ST	Q9H9Q4	NHEJ1	P78527	PRKDC	T266	P270H	270	Missense	distal	4	no	10.476	10.485	PhosphoSitePlus;EPSD	TCGA;ICGC;COSMIC	8.283	Up-regulation
Atypical_PIKK_DNAPK_PRKDC_ST	P07900	HSP90AA1	P78527	PRKDC	T5	P2L	2	Missense	distal	-3	no	13.034	12.834	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	8.283	Down-regulation
Atypical_PIKK_DNAPK_PRKDC_ST	P07900	HSP90AA1	P78527	PRKDC	T7	P2L	2	Missense	distal	-5	no	15.903	15.915	PhosphoSitePlus;EPSD	TCGA;ICGC;COSMIC	8.283	Up-regulation
Atypical_PIKK_DNAPK_PRKDC_ST	P13010	XRCC5	P78527	PRKDC	S102	L108M	108	Missense	distal	6	no	12.610	12.593	EPSD	TCGA;ICGC;COSMIC	8.283	Down-regulation
Atypical_PIKK_DNAPK_PRKDC_ST	P13010	XRCC5	P78527	PRKDC	S145	R141Q	141	Missense	distal	-4	no	12.692	13.390	EPSD	TCGA;ICGC;COSMIC	8.283	Up-regulation
Atypical_PIKK_DNAPK_PRKDC_ST	P13010	XRCC5	P78527	PRKDC	S153	K155N	155	Missense	proximal	2	no	7.896	8.317	EPSD	TCGA;ICGC;COSMIC	8.283	Gain
Atypical_PIKK_DNAPK_PRKDC_ST	P13010	XRCC5	P78527	PRKDC	S379	I381L	381	Missense	proximal	2	no	7.285	8.959	EPSD	TCGA;ICGC;COSMIC	8.283	Gain
Atypical_PIKK_DNAPK_PRKDC_ST	P13010	XRCC5	P78527	PRKDC	T549	V548A	548	Missense	proximal	-1	no	7.270	8.581	EPSD	TCGA;ICGC	8.283	Gain
Atypical_PIKK_DNAPK_PRKDC_ST	P13010	XRCC5	P78527	PRKDC	S712	P711R	711	Missense	proximal	-1	no	8.864	7.783	EPSD	TCGA;ICGC;COSMIC	8.283	Loss
Atypical_PIKK_DNAPK_PRKDC_ST	P13010	XRCC5	P78527	PRKDC	S712	D714N	714	Missense	proximal	2	no	8.864	6.921	EPSD	TCGA;ICGC;COSMIC	8.283	Loss
Atypical_PIKK_DNAPK_PRKDC_ST	P13010	XRCC5	P78527	PRKDC	S712	D709G	709	Missense	distal	-3	no	8.864	8.698	EPSD	TCGA;ICGC	8.283	Down-regulation
Atypical_PIKK_DNAPK_PRKDC_ST	P13010	XRCC5	P78527	PRKDC	S712	A717D	717	Missense	distal	5	no	8.864	8.917	EPSD	TCGA;ICGC;COSMIC	8.283	Up-regulation
Atypical_PIKK_DNAPK_PRKDC_ST	P13010	XRCC5	P78527	PRKDC	T715	P711R	711	Missense	distal	-4	no	8.413	8.219	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	8.283	Loss
Atypical_PIKK_DNAPK_PRKDC_ST	P13010	XRCC5	P78527	PRKDC	T715	D714N	714	Missense	proximal	-1	no	8.413	7.672	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	8.283	Loss
Atypical_PIKK_DNAPK_PRKDC_ST	P13010	XRCC5	P78527	PRKDC	T715	D709G	709	Missense	distal	-6	no	8.413	8.229	EPSD;PhosphoSitePlus	TCGA;ICGC	8.283	Loss
Atypical_PIKK_DNAPK_PRKDC_ST	P13010	XRCC5	P78527	PRKDC	T715	A717D	717	Missense	proximal	2	no	8.413	9.461	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	8.283	Up-regulation
Atypical_PIKK_DNAPK_PRKDC_ST	P46527	CDKN1B	P78527	PRKDC	S10	S7C	7	Missense	distal	-3	no	9.159	8.922	EPSD	TCGA;ICGC;COSMIC	8.283	Down-regulation
Atypical_PIKK_DNAPK_PRKDC_ST	P46527	CDKN1B	P78527	PRKDC	S10	G9W	9	Missense	proximal	-1	no	9.159	8.329	EPSD	TCGA;ICGC;COSMIC	8.283	Down-regulation
Atypical_PIKK_DNAPK_PRKDC_ST	P46527	CDKN1B	P78527	PRKDC	S12	S7C	7	Missense	distal	-5	no	10.753	10.295	EPSD	TCGA;ICGC;COSMIC	8.283	Down-regulation
Atypical_PIKK_DNAPK_PRKDC_ST	P46527	CDKN1B	P78527	PRKDC	S12	G9W	9	Missense	distal	-3	no	10.753	10.516	EPSD	TCGA;ICGC;COSMIC	8.283	Down-regulation
Atypical_PIKK_DNAPK_PRKDC_ST	P46527	CDKN1B	P78527	PRKDC	S106	A103V	103	Missense	distal	-3	no	12.199	12.016	EPSD	TCGA;ICGC	8.283	Down-regulation
Atypical_PIKK_DNAPK_PRKDC_ST	P46527	CDKN1B	P78527	PRKDC	S110	A103V	103	Missense	distal	-7	no	8.649	7.727	EPSD	TCGA;ICGC	8.283	Loss
Atypical_PIKK_DNAPK_PRKDC_ST	P46527	CDKN1B	P78527	PRKDC	S140	E146K	146	Missense	distal	6	no	14.217	14.186	PhosphoSitePlus	TCGA;ICGC;COSMIC	8.283	Down-regulation
Atypical_PIKK_DNAPK_PRKDC_ST	P19838	NFKB1	P78527	PRKDC	S80	S74C	74	Missense	distal	-6	no	8.663	7.804	EPSD	TCGA	8.283	Loss
Atypical_PIKK_DNAPK_PRKDC_ST	P19838	NFKB1	P78527	PRKDC	S80	K79N	79	Missense	proximal	-1	no	8.663	9.262	EPSD	TCGA;COSMIC	8.283	Up-regulation
Atypical_PIKK_DNAPK_PRKDC_ST	P19838	NFKB1	P78527	PRKDC	S907	Q914H	914	Missense	distal	7	no	9.433	9.343	EPSD	TCGA;COSMIC	8.283	Down-regulation
Atypical_PIKK_DNAPK_PRKDC_ST	Q00839	HNRNPU	P78527	PRKDC	S59	G58C	58	Missense	proximal	-1	no	11.311	10.893	PhosphoSitePlus	TCGA;ICGC;COSMIC	8.283	Down-regulation
Atypical_PIKK_DNAPK_PRKDC_ST	Q00839	HNRNPU	P78527	PRKDC	S326	G328A	328	Missense	proximal	2	no	7.962	8.710	EPSD	TCGA;ICGC;COSMIC	8.283	Gain
Atypical_PIKK_DNAPK_PRKDC_ST	Q00839	HNRNPU	P78527	PRKDC	T351	K352Q	352	Missense	proximal	1	no	-1.486	9.719	EPSD	TCGA;ICGC;COSMIC	8.283	Gain
Atypical_PIKK_DNAPK_PRKDC_ST	Q00839	HNRNPU	P78527	PRKDC	S382	Y381C	381	Missense	proximal	-1	no	9.953	8.934	EPSD	TCGA	8.283	Down-regulation
Atypical_PIKK_DNAPK_PRKDC_ST	Q00839	HNRNPU	P78527	PRKDC	S382	S378A	378	Missense	distal	-4	no	9.953	9.879	EPSD	TCGA;ICGC;COSMIC	8.283	Down-regulation
Atypical_PIKK_DNAPK_PRKDC_ST	Q00839	HNRNPU	P78527	PRKDC	S799	R793C	793	Missense	distal	-6	no	13.660	13.305	EPSD	TCGA;ICGC;COSMIC	8.283	Down-regulation
Atypical_PIKK_DNAPK_PRKDC_ST	Q00839	HNRNPU	P78527	PRKDC	S799	S799F	799	Missense	central	0	yes	13.660	0.000	EPSD	TCGA;ICGC;COSMIC	8.283	Loss
Atypical_PIKK_DNAPK_PRKDC_ST	Q00839	HNRNPU	P78527	PRKDC	S817	W811C	811	Missense	distal	-6	no	13.216	13.348	EPSD	TCGA;ICGC;COSMIC	8.283	Up-regulation
Atypical_PIKK_DNAPK_PRKDC_ST	Q00839	HNRNPU	P78527	PRKDC	S817	Y824C	824	Missense	distal	7	no	13.216	12.211	EPSD	TCGA;ICGC;COSMIC	8.283	Down-regulation
Atypical_PIKK_DNAPK_PRKDC_ST	Q00839	HNRNPU	P78527	PRKDC	S817	H821R	821	Missense	distal	4	no	13.216	13.195	EPSD	TCGA;ICGC;COSMIC	8.283	Down-regulation
Atypical_PIKK_DNAPK_PRKDC_ST	P15927	RPA2	P78527	PRKDC	S8	F6L	6	Missense	proximal	-2	no	9.806	9.784	EPSD;PhosphoSitePlus	TCGA	8.283	Down-regulation
Atypical_PIKK_DNAPK_PRKDC_ST	P15927	RPA2	P78527	PRKDC	S13	G19D	19	Missense	distal	6	no	9.212	9.231	EPSD	TCGA;COSMIC	8.283	Up-regulation
Atypical_PIKK_DNAPK_PRKDC_ST	P15927	RPA2	P78527	PRKDC	S13	F6L	6	Missense	distal	-7	no	9.212	9.289	EPSD	TCGA	8.283	Up-regulation
Atypical_PIKK_DNAPK_PRKDC_ST	P15927	RPA2	P78527	PRKDC	T21	T21P	21	Missense	central	0	yes	13.040	0.000	EPSD;PhosphoSitePlus	TCGA	8.283	Loss
Atypical_PIKK_DNAPK_PRKDC_ST	P15927	RPA2	P78527	PRKDC	T21	S23F	23	Missense	proximal	2	no	13.040	11.938	EPSD;PhosphoSitePlus	TCGA;COSMIC	8.283	Down-regulation
Atypical_PIKK_DNAPK_PRKDC_ST	P15927	RPA2	P78527	PRKDC	T21	G19D	19	Missense	proximal	-2	no	13.040	12.923	EPSD;PhosphoSitePlus	TCGA;COSMIC	8.283	Down-regulation
Atypical_PIKK_DNAPK_PRKDC_ST	P15927	RPA2	P78527	PRKDC	T21	G26S	26	Missense	distal	5	no	13.040	13.156	EPSD;PhosphoSitePlus	TCGA;COSMIC	8.283	Up-regulation
Atypical_PIKK_DNAPK_PRKDC_ST	P15927	RPA2	P78527	PRKDC	S23	T21P	21	Missense	proximal	-2	no	12.207	12.162	EPSD;PhosphoSitePlus	TCGA	8.283	Down-regulation
Atypical_PIKK_DNAPK_PRKDC_ST	P15927	RPA2	P78527	PRKDC	S23	S23F	23	Missense	central	0	yes	12.207	0.000	EPSD;PhosphoSitePlus	TCGA;COSMIC	8.283	Loss
Atypical_PIKK_DNAPK_PRKDC_ST	P15927	RPA2	P78527	PRKDC	S23	S29L	29	Missense	distal	6	no	12.207	12.205	EPSD;PhosphoSitePlus	TCGA;COSMIC	8.283	Down-regulation
Atypical_PIKK_DNAPK_PRKDC_ST	P15927	RPA2	P78527	PRKDC	S23	G19D	19	Missense	distal	-4	no	12.207	12.594	EPSD;PhosphoSitePlus	TCGA;COSMIC	8.283	Up-regulation
Atypical_PIKK_DNAPK_PRKDC_ST	P15927	RPA2	P78527	PRKDC	S23	G26S	26	Missense	distal	3	no	12.207	12.467	EPSD;PhosphoSitePlus	TCGA;COSMIC	8.283	Up-regulation
Atypical_PIKK_DNAPK_PRKDC_ST	P15927	RPA2	P78527	PRKDC	S29	S23F	23	Missense	distal	-6	no	11.749	11.258	PhosphoSitePlus;EPSD	TCGA;COSMIC	8.283	Down-regulation
Atypical_PIKK_DNAPK_PRKDC_ST	P15927	RPA2	P78527	PRKDC	S29	E36A	36	Missense	distal	7	no	11.749	11.500	PhosphoSitePlus;EPSD	TCGA;COSMIC	8.283	Down-regulation
Atypical_PIKK_DNAPK_PRKDC_ST	P15927	RPA2	P78527	PRKDC	S29	S29L	29	Missense	central	0	yes	11.749	0.000	PhosphoSitePlus;EPSD	TCGA;COSMIC	8.283	Loss
Atypical_PIKK_DNAPK_PRKDC_ST	P15927	RPA2	P78527	PRKDC	S29	G26S	26	Missense	distal	-3	no	11.749	11.906	PhosphoSitePlus;EPSD	TCGA;COSMIC	8.283	Up-regulation
Atypical_PIKK_DNAPK_PRKDC_ST	P15927	RPA2	P78527	PRKDC	S33	E36A	36	Missense	distal	3	no	11.665	11.358	EPSD;PhosphoSitePlus	TCGA;COSMIC	8.283	Down-regulation
Atypical_PIKK_DNAPK_PRKDC_ST	P15927	RPA2	P78527	PRKDC	S33	S29L	29	Missense	distal	-4	no	11.665	11.220	EPSD;PhosphoSitePlus	TCGA;COSMIC	8.283	Down-regulation
Atypical_PIKK_DNAPK_PRKDC_ST	P15927	RPA2	P78527	PRKDC	S33	G26S	26	Missense	distal	-7	no	11.665	12.208	EPSD;PhosphoSitePlus	TCGA;COSMIC	8.283	Up-regulation
Atypical_PIKK_DNAPK_PRKDC_ST	P15927	RPA2	P78527	PRKDC	S52	Q53H	53	Missense	proximal	1	no	9.616	-0.719	EPSD	TCGA;COSMIC	8.283	Loss
Atypical_PIKK_DNAPK_PRKDC_ST	P15927	RPA2	P78527	PRKDC	S52	A57V	57	Missense	distal	5	no	9.616	9.438	EPSD	TCGA;COSMIC	8.283	Down-regulation
Atypical_PIKK_DNAPK_PRKDC_ST	P24928	POLR2A	P78527	PRKDC	S27	F23L	23	Missense	distal	-4	no	11.215	11.285	EPSD	TCGA;ICGC;COSMIC	8.283	Up-regulation
Atypical_PIKK_DNAPK_PRKDC_ST	P24928	POLR2A	P78527	PRKDC	S209	L215R	215	Missense	distal	6	no	13.680	13.662	EPSD	TCGA;ICGC;COSMIC	8.283	Down-regulation
Atypical_PIKK_DNAPK_PRKDC_ST	P24928	POLR2A	P78527	PRKDC	S209	L215P	215	Missense	distal	6	no	13.680	13.691	EPSD	TCGA;ICGC	8.283	Up-regulation
Atypical_PIKK_DNAPK_PRKDC_ST	P24928	POLR2A	P78527	PRKDC	T732	G730W	730	Missense	proximal	-2	no	8.341	8.497	EPSD	TCGA;ICGC	8.283	Up-regulation
Atypical_PIKK_DNAPK_PRKDC_ST	P24928	POLR2A	P78527	PRKDC	T1568	G1570S	1570	Missense	proximal	2	no	7.576	8.352	EPSD	TCGA;ICGC	8.283	Gain
Atypical_PIKK_DNAPK_PRKDC_ST	P24928	POLR2A	P78527	PRKDC	S1574	P1572L	1572	Missense	proximal	-2	no	9.448	9.446	EPSD	TCGA;ICGC	8.283	Down-regulation
Atypical_PIKK_DNAPK_PRKDC_ST	P24928	POLR2A	P78527	PRKDC	S1574	G1570S	1570	Missense	distal	-4	no	9.448	9.893	EPSD	TCGA;ICGC	8.283	Up-regulation
Atypical_PIKK_DNAPK_PRKDC_ST	P24928	POLR2A	P78527	PRKDC	S1590	P1591L	1591	Missense	proximal	1	no	8.743	8.682	EPSD	TCGA;ICGC	8.283	Down-regulation
Atypical_PIKK_DNAPK_PRKDC_ST	P24928	POLR2A	P78527	PRKDC	S1592	P1591L	1591	Missense	proximal	-1	no	9.721	9.419	EPSD	TCGA;ICGC	8.283	Down-regulation
Atypical_PIKK_DNAPK_PRKDC_ST	P24928	POLR2A	P78527	PRKDC	S1594	P1591L	1591	Missense	distal	-3	no	9.500	9.300	EPSD	TCGA;ICGC	8.283	Down-regulation
Atypical_PIKK_DNAPK_PRKDC_ST	P24928	POLR2A	P78527	PRKDC	S1619	T1625A	1625	Missense	distal	6	no	8.764	8.768	EPSD	TCGA;ICGC	8.283	Up-regulation
Atypical_PIKK_DNAPK_PRKDC_ST	P24928	POLR2A	P78527	PRKDC	S1621	T1625A	1625	Missense	distal	4	no	9.489	9.549	EPSD;PhosphoSitePlus	TCGA;ICGC	8.283	Up-regulation
Atypical_PIKK_DNAPK_PRKDC_ST	P24928	POLR2A	P78527	PRKDC	S1626	T1625A	1625	Missense	proximal	-1	no	9.182	10.076	EPSD	TCGA;ICGC	8.283	Up-regulation
Atypical_PIKK_DNAPK_PRKDC_ST	P24928	POLR2A	P78527	PRKDC	S1626	S1630Y	1630	Missense	distal	4	no	9.182	9.189	EPSD	TCGA	8.283	Up-regulation
Atypical_PIKK_DNAPK_PRKDC_ST	P24928	POLR2A	P78527	PRKDC	S1626	P1631S	1631	Missense	distal	5	no	9.182	9.214	EPSD	TCGA;ICGC	8.283	Up-regulation
Atypical_PIKK_DNAPK_PRKDC_ST	P24928	POLR2A	P78527	PRKDC	S1626	P1631L	1631	Missense	distal	5	no	9.182	9.137	EPSD	TCGA;ICGC	8.283	Down-regulation
Atypical_PIKK_DNAPK_PRKDC_ST	P24928	POLR2A	P78527	PRKDC	S1670	S1677N	1677	Missense	distal	7	no	9.950	9.392	EPSD	TCGA;ICGC	8.283	Down-regulation
Atypical_PIKK_DNAPK_PRKDC_ST	P24928	POLR2A	P78527	PRKDC	S1675	S1677N	1677	Missense	proximal	2	no	8.429	7.507	EPSD	TCGA;ICGC	8.283	Loss
Atypical_PIKK_DNAPK_PRKDC_ST	P24928	POLR2A	P78527	PRKDC	S1677	S1677N	1677	Missense	central	0	yes	9.950	0.000	EPSD	TCGA;ICGC	8.283	Loss
Atypical_PIKK_DNAPK_PRKDC_ST	P24928	POLR2A	P78527	PRKDC	S1682	S1677N	1677	Missense	distal	-5	no	8.429	8.275	EPSD	TCGA;ICGC	8.283	Loss
Atypical_PIKK_DNAPK_PRKDC_ST	P24928	POLR2A	P78527	PRKDC	S1684	S1677N	1677	Missense	distal	-7	no	9.950	9.634	EPSD	TCGA;ICGC	8.283	Down-regulation
Atypical_PIKK_DNAPK_PRKDC_ST	P24928	POLR2A	P78527	PRKDC	S1689	T1695M	1695	Missense	distal	6	no	8.429	8.415	EPSD	TCGA;ICGC	8.283	Down-regulation
Atypical_PIKK_DNAPK_PRKDC_ST	P24928	POLR2A	P78527	PRKDC	S1691	T1695M	1695	Missense	distal	4	no	9.950	9.962	EPSD	TCGA;ICGC	8.283	Up-regulation
Atypical_PIKK_DNAPK_PRKDC_ST	P24928	POLR2A	P78527	PRKDC	S1696	T1702I	1702	Missense	distal	6	no	8.429	8.398	EPSD	TCGA;ICGC	8.283	Down-regulation
Atypical_PIKK_DNAPK_PRKDC_ST	P24928	POLR2A	P78527	PRKDC	S1696	T1702S	1702	Missense	distal	6	no	8.429	8.434	EPSD	TCGA;ICGC	8.283	Up-regulation
Atypical_PIKK_DNAPK_PRKDC_ST	P24928	POLR2A	P78527	PRKDC	S1696	T1695M	1695	Missense	proximal	-1	no	8.429	8.059	EPSD	TCGA;ICGC	8.283	Loss
Atypical_PIKK_DNAPK_PRKDC_ST	P24928	POLR2A	P78527	PRKDC	S1696	S1700L	1700	Missense	distal	4	no	8.429	8.410	EPSD	TCGA;ICGC	8.283	Down-regulation
Atypical_PIKK_DNAPK_PRKDC_ST	P24928	POLR2A	P78527	PRKDC	S1698	T1702I	1702	Missense	distal	4	no	9.950	9.919	EPSD	TCGA;ICGC	8.283	Down-regulation
Atypical_PIKK_DNAPK_PRKDC_ST	P24928	POLR2A	P78527	PRKDC	S1698	T1702S	1702	Missense	distal	4	no	9.950	9.992	EPSD	TCGA;ICGC	8.283	Up-regulation
Atypical_PIKK_DNAPK_PRKDC_ST	P24928	POLR2A	P78527	PRKDC	S1698	T1695M	1695	Missense	distal	-3	no	9.950	9.807	EPSD	TCGA;ICGC	8.283	Down-regulation
Atypical_PIKK_DNAPK_PRKDC_ST	P24928	POLR2A	P78527	PRKDC	S1698	S1700L	1700	Missense	proximal	2	no	9.950	8.762	EPSD	TCGA;ICGC	8.283	Down-regulation
Atypical_PIKK_DNAPK_PRKDC_ST	P24928	POLR2A	P78527	PRKDC	S1703	T1702I	1702	Missense	proximal	-1	no	8.429	7.548	EPSD	TCGA;ICGC	8.283	Loss
Atypical_PIKK_DNAPK_PRKDC_ST	P24928	POLR2A	P78527	PRKDC	S1703	T1702S	1702	Missense	proximal	-1	no	8.429	8.915	EPSD	TCGA;ICGC	8.283	Up-regulation
Atypical_PIKK_DNAPK_PRKDC_ST	P24928	POLR2A	P78527	PRKDC	S1703	S1700L	1700	Missense	distal	-3	no	8.429	8.367	EPSD	TCGA;ICGC	8.283	Down-regulation
Atypical_PIKK_DNAPK_PRKDC_ST	P24928	POLR2A	P78527	PRKDC	S1705	T1702I	1702	Missense	distal	-3	no	9.950	9.567	EPSD	TCGA;ICGC	8.283	Down-regulation
Atypical_PIKK_DNAPK_PRKDC_ST	P24928	POLR2A	P78527	PRKDC	S1705	T1702S	1702	Missense	distal	-3	no	9.950	10.074	EPSD	TCGA;ICGC	8.283	Up-regulation
Atypical_PIKK_DNAPK_PRKDC_ST	P24928	POLR2A	P78527	PRKDC	S1705	S1700L	1700	Missense	distal	-5	no	9.950	9.592	EPSD	TCGA;ICGC	8.283	Down-regulation
Atypical_PIKK_DNAPK_PRKDC_ST	P24928	POLR2A	P78527	PRKDC	S1726	P1732L	1732	Missense	distal	6	no	10.143	10.132	EPSD	TCGA;ICGC;CCLE	8.283	Down-regulation
Atypical_PIKK_DNAPK_PRKDC_ST	P24928	POLR2A	P78527	PRKDC	S1731	P1732L	1732	Missense	proximal	1	no	8.422	8.361	EPSD	TCGA;ICGC;CCLE	8.283	Down-regulation
Atypical_PIKK_DNAPK_PRKDC_ST	P24928	POLR2A	P78527	PRKDC	S1731	S1735A	1735	Missense	distal	4	no	8.422	8.441	EPSD	TCGA;ICGC	8.283	Up-regulation
Atypical_PIKK_DNAPK_PRKDC_ST	P24928	POLR2A	P78527	PRKDC	S1733	P1732L	1732	Missense	proximal	-1	no	9.944	9.643	EPSD	TCGA;ICGC;CCLE	8.283	Down-regulation
Atypical_PIKK_DNAPK_PRKDC_ST	P24928	POLR2A	P78527	PRKDC	S1733	S1735A	1735	Missense	proximal	2	no	9.944	9.917	EPSD	TCGA;ICGC	8.283	Down-regulation
Atypical_PIKK_DNAPK_PRKDC_ST	P24928	POLR2A	P78527	PRKDC	S1738	T1744I	1744	Missense	distal	6	no	8.429	8.398	EPSD	TCGA;ICGC	8.283	Down-regulation
Atypical_PIKK_DNAPK_PRKDC_ST	P24928	POLR2A	P78527	PRKDC	S1738	S1745N	1745	Missense	distal	7	no	8.429	7.871	EPSD	TCGA;ICGC	8.283	Loss
Atypical_PIKK_DNAPK_PRKDC_ST	P24928	POLR2A	P78527	PRKDC	S1738	P1732L	1732	Missense	distal	-6	no	8.429	8.548	EPSD	TCGA;ICGC;CCLE	8.283	Up-regulation
Atypical_PIKK_DNAPK_PRKDC_ST	P24928	POLR2A	P78527	PRKDC	S1738	S1735A	1735	Missense	distal	-3	no	8.429	8.365	EPSD	TCGA;ICGC	8.283	Down-regulation
Atypical_PIKK_DNAPK_PRKDC_ST	P24928	POLR2A	P78527	PRKDC	S1815	P1809S	1809	Missense	distal	-6	no	8.248	8.612	EPSD	TCGA;ICGC	8.283	Gain
Atypical_PIKK_DNAPK_PRKDC_ST	P24928	POLR2A	P78527	PRKDC	T1819	P1816A	1816	Missense	distal	-3	no	9.017	8.815	EPSD	TCGA;ICGC	8.283	Down-regulation
Atypical_PIKK_DNAPK_PRKDC_ST	P24928	POLR2A	P78527	PRKDC	T1819	Y1818C	1818	Missense	proximal	-1	no	9.017	7.998	EPSD	TCGA	8.283	Loss
Atypical_PIKK_DNAPK_PRKDC_ST	P24928	POLR2A	P78527	PRKDC	S1822	P1816A	1816	Missense	distal	-6	no	8.658	9.065	EPSD	TCGA;ICGC	8.283	Up-regulation
Atypical_PIKK_DNAPK_PRKDC_ST	P24928	POLR2A	P78527	PRKDC	S1822	Y1818C	1818	Missense	distal	-4	no	8.658	8.162	EPSD	TCGA	8.283	Loss
Atypical_PIKK_DNAPK_PRKDC_ST	P24928	POLR2A	P78527	PRKDC	S1824	Y1818C	1818	Missense	distal	-6	no	9.842	9.379	EPSD	TCGA	8.283	Down-regulation
Atypical_PIKK_DNAPK_PRKDC_ST	P24928	POLR2A	P78527	PRKDC	S1843	S1845P	1845	Missense	proximal	2	no	8.811	8.580	EPSD	TCGA;GDSC;CCLE	8.283	Down-regulation
Atypical_PIKK_DNAPK_PRKDC_ST	P24928	POLR2A	P78527	PRKDC	S1843	S1845Y	1845	Missense	proximal	2	no	8.811	7.881	EPSD	TCGA;ICGC	8.283	Loss
Atypical_PIKK_DNAPK_PRKDC_ST	P24928	POLR2A	P78527	PRKDC	S1845	S1845P	1845	Missense	central	0	yes	9.704	0.000	EPSD	TCGA;GDSC;CCLE	8.283	Loss
Atypical_PIKK_DNAPK_PRKDC_ST	P24928	POLR2A	P78527	PRKDC	S1845	S1845Y	1845	Missense	central	0	yes	9.704	0.000	EPSD	TCGA;ICGC	8.283	Loss
Atypical_PIKK_DNAPK_PRKDC_ST	P24928	POLR2A	P78527	PRKDC	S1847	S1845P	1845	Missense	proximal	-2	no	8.448	8.473	EPSD	TCGA;GDSC;CCLE	8.283	Up-regulation
Atypical_PIKK_DNAPK_PRKDC_ST	P24928	POLR2A	P78527	PRKDC	S1847	S1845Y	1845	Missense	proximal	-2	no	8.448	8.399	EPSD	TCGA;ICGC	8.283	Down-regulation
Atypical_PIKK_DNAPK_PRKDC_ST	P24928	POLR2A	P78527	PRKDC	S1850	S1845P	1845	Missense	distal	-5	no	10.395	10.024	EPSD	TCGA;GDSC;CCLE	8.283	Down-regulation
Atypical_PIKK_DNAPK_PRKDC_ST	P24928	POLR2A	P78527	PRKDC	S1850	S1857C	1857	Missense	distal	7	no	10.395	8.935	EPSD	TCGA;ICGC	8.283	Down-regulation
Atypical_PIKK_DNAPK_PRKDC_ST	P24928	POLR2A	P78527	PRKDC	S1850	S1845Y	1845	Missense	distal	-5	no	10.395	10.049	EPSD	TCGA;ICGC	8.283	Down-regulation
Atypical_PIKK_DNAPK_PRKDC_ST	P24928	POLR2A	P78527	PRKDC	S1850	S1857F	1857	Missense	distal	7	no	10.395	9.693	EPSD	TCGA	8.283	Down-regulation
Atypical_PIKK_DNAPK_PRKDC_ST	P24928	POLR2A	P78527	PRKDC	S1868	Y1874H	1874	Missense	distal	6	no	8.412	8.406	EPSD	TCGA;ICGC	8.283	Down-regulation
Atypical_PIKK_DNAPK_PRKDC_ST	P24928	POLR2A	P78527	PRKDC	S1868	S1875L	1875	Missense	distal	7	no	8.412	7.657	EPSD	TCGA;ICGC	8.283	Loss
Atypical_PIKK_DNAPK_PRKDC_ST	P24928	POLR2A	P78527	PRKDC	T1880	Y1874H	1874	Missense	distal	-6	no	8.458	8.709	EPSD	TCGA;ICGC	8.283	Up-regulation
Atypical_PIKK_DNAPK_PRKDC_ST	P24928	POLR2A	P78527	PRKDC	T1880	S1875L	1875	Missense	distal	-5	no	8.458	8.100	EPSD	TCGA;ICGC	8.283	Loss
Atypical_PIKK_DNAPK_PRKDC_ST	P24928	POLR2A	P78527	PRKDC	T1880	K1887N	1887	Missense	distal	7	no	8.458	8.695	EPSD	TCGA;ICGC	8.283	Up-regulation
Atypical_PIKK_DNAPK_PRKDC_ST	P24928	POLR2A	P78527	PRKDC	T1894	T1898A	1898	Missense	distal	4	no	8.292	8.353	EPSD	TCGA;ICGC	8.283	Up-regulation
Atypical_PIKK_DNAPK_PRKDC_ST	P24928	POLR2A	P78527	PRKDC	T1894	S1896F	1896	Missense	proximal	2	no	8.292	7.191	EPSD	TCGA;ICGC	8.283	Loss
Atypical_PIKK_DNAPK_PRKDC_ST	P24928	POLR2A	P78527	PRKDC	T1894	K1887N	1887	Missense	distal	-7	no	8.292	8.185	EPSD	TCGA;ICGC	8.283	Loss
Atypical_PIKK_DNAPK_PRKDC_ST	P24928	POLR2A	P78527	PRKDC	S1896	T1898A	1898	Missense	proximal	2	no	7.336	8.293	EPSD	TCGA;ICGC	8.283	Gain
Atypical_PIKK_DNAPK_PRKDC_ST	P24928	POLR2A	P78527	PRKDC	S1924	S1931L	1931	Missense	distal	7	no	8.669	7.915	EPSD	TCGA;ICGC	8.283	Loss
Atypical_PIKK_DNAPK_PRKDC_ST	P24928	POLR2A	P78527	PRKDC	S1931	S1931L	1931	Missense	central	0	yes	9.179	0.000	EPSD	TCGA;ICGC	8.283	Loss
Atypical_PIKK_DNAPK_PRKDC_ST	P24928	POLR2A	P78527	PRKDC	S1948	S1944F	1944	Missense	distal	-4	no	8.370	7.854	EPSD	TCGA;ICGC	8.283	Loss
Atypical_PIKK_DNAPK_PRKDC_ST	P24928	POLR2A	P78527	PRKDC	S1951	S1944F	1944	Missense	distal	-7	no	8.952	8.407	EPSD	TCGA;ICGC	8.283	Down-regulation
Atypical_PIKK_DNAPK_PRKDC_ST	P24928	POLR2A	P78527	PRKDC	S1955	I1961M	1961	Missense	distal	6	no	8.902	8.920	EPSD	TCGA;ICGC	8.283	Up-regulation
Atypical_PIKK_DNAPK_PRKDC_ST	P24928	POLR2A	P78527	PRKDC	S1962	I1961M	1961	Missense	proximal	-1	no	8.871	9.382	EPSD	TCGA;ICGC	8.283	Up-regulation
Atypical_PIKK_DNAPK_PRKDC_ST	P24928	POLR2A	P78527	PRKDC	S1966	I1961M	1961	Missense	distal	-5	no	8.986	9.457	EPSD	TCGA;ICGC	8.283	Up-regulation
Atypical_PIKK_DNAPK_PRKDC_ST	Q15648	MED1	P78527	PRKDC	S18	R22Q	22	Missense	distal	4	no	10.981	11.048	EPSD	TCGA;ICGC;COSMIC	8.283	Up-regulation
Atypical_PIKK_DNAPK_PRKDC_ST	Q15648	MED1	P78527	PRKDC	S18	A25T	25	Missense	distal	7	no	10.981	10.364	EPSD	TCGA;ICGC;COSMIC	8.283	Down-regulation
Atypical_PIKK_DNAPK_PRKDC_ST	Q15648	MED1	P78527	PRKDC	T212	H218Y	218	Missense	distal	6	no	9.524	9.530	EPSD	TCGA;ICGC;COSMIC	8.283	Up-regulation
Atypical_PIKK_DNAPK_PRKDC_ST	Q15648	MED1	P78527	PRKDC	T212	G209V	209	Missense	distal	-3	no	9.524	9.434	EPSD	TCGA;ICGC;COSMIC	8.283	Down-regulation
Atypical_PIKK_DNAPK_PRKDC_ST	Q15648	MED1	P78527	PRKDC	S387	P381A	381	Missense	distal	-6	no	9.550	9.957	EPSD	TCGA;ICGC;COSMIC	8.283	Up-regulation
Atypical_PIKK_DNAPK_PRKDC_ST	Q15648	MED1	P78527	PRKDC	S387	S387R	387	Missense	central	0	yes	9.550	0.000	EPSD	TCGA	8.283	Loss
Atypical_PIKK_DNAPK_PRKDC_ST	Q15648	MED1	P78527	PRKDC	S387	L382F	382	Missense	distal	-5	no	9.550	9.498	EPSD	TCGA;ICGC;COSMIC	8.283	Down-regulation
Atypical_PIKK_DNAPK_PRKDC_ST	Q15648	MED1	P78527	PRKDC	T522	P523Q	523	Missense	proximal	1	no	7.151	11.632	EPSD	TCGA;ICGC;COSMIC	8.283	Gain
Atypical_PIKK_DNAPK_PRKDC_ST	Q15648	MED1	P78527	PRKDC	S599	L604V	604	Missense	distal	5	no	10.103	10.023	EPSD	TCGA;ICGC;COSMIC	8.283	Down-regulation
Atypical_PIKK_DNAPK_PRKDC_ST	Q15648	MED1	P78527	PRKDC	T623	T628M	628	Missense	distal	5	no	9.843	9.761	EPSD	TCGA;ICGC	8.283	Down-regulation
Atypical_PIKK_DNAPK_PRKDC_ST	Q15648	MED1	P78527	PRKDC	T623	P625A	625	Missense	proximal	2	no	9.843	10.047	EPSD	TCGA;ICGC;COSMIC	8.283	Up-regulation
Atypical_PIKK_DNAPK_PRKDC_ST	Q15648	MED1	P78527	PRKDC	T623	H627D	627	Missense	distal	4	no	9.843	9.857	EPSD	TCGA;ICGC;COSMIC	8.283	Up-regulation
Atypical_PIKK_DNAPK_PRKDC_ST	Q15648	MED1	P78527	PRKDC	T628	T628M	628	Missense	central	0	yes	8.665	0.000	EPSD	TCGA;ICGC	8.283	Loss
Atypical_PIKK_DNAPK_PRKDC_ST	Q15648	MED1	P78527	PRKDC	T628	P625A	625	Missense	distal	-3	no	8.665	8.463	EPSD	TCGA;ICGC;COSMIC	8.283	Down-regulation
Atypical_PIKK_DNAPK_PRKDC_ST	Q15648	MED1	P78527	PRKDC	T628	S634L	634	Missense	distal	6	no	8.665	8.663	EPSD	TCGA;ICGC;COSMIC	8.283	Down-regulation
Atypical_PIKK_DNAPK_PRKDC_ST	Q15648	MED1	P78527	PRKDC	T628	H627D	627	Missense	proximal	-1	no	8.665	9.104	EPSD	TCGA;ICGC;COSMIC	8.283	Up-regulation
Atypical_PIKK_DNAPK_PRKDC_ST	Q15648	MED1	P78527	PRKDC	S675	R677H	677	Missense	proximal	2	no	7.921	8.816	EPSD	TCGA;ICGC;COSMIC;GDSC;CCLE	8.283	Gain
Atypical_PIKK_DNAPK_PRKDC_ST	Q15648	MED1	P78527	PRKDC	S719	D725N	725	Missense	distal	6	no	10.712	10.708	EPSD	TCGA;ICGC;COSMIC	8.283	Down-regulation
Atypical_PIKK_DNAPK_PRKDC_ST	Q15648	MED1	P78527	PRKDC	S719	S714L	714	Missense	distal	-5	no	10.712	10.354	EPSD	TCGA;ICGC;COSMIC	8.283	Down-regulation
Atypical_PIKK_DNAPK_PRKDC_ST	Q15648	MED1	P78527	PRKDC	S816	S810Y	810	Missense	distal	-6	no	13.784	13.389	EPSD	TCGA;ICGC;COSMIC	8.283	Down-regulation
Atypical_PIKK_DNAPK_PRKDC_ST	Q15648	MED1	P78527	PRKDC	S816	Q817K	817	Missense	proximal	1	no	13.784	2.579	EPSD	TCGA;ICGC;COSMIC	8.283	Loss
Atypical_PIKK_DNAPK_PRKDC_ST	Q15648	MED1	P78527	PRKDC	S816	S816Y	816	Missense	central	0	yes	13.784	0.000	EPSD	TCGA;ICGC;COSMIC	8.283	Loss
Atypical_PIKK_DNAPK_PRKDC_ST	Q15648	MED1	P78527	PRKDC	S853	G847R	847	Missense	distal	-6	no	8.591	8.382	EPSD	TCGA;ICGC;COSMIC	8.283	Down-regulation
Atypical_PIKK_DNAPK_PRKDC_ST	Q15648	MED1	P78527	PRKDC	S872	N871S	871	Missense	proximal	-1	no	12.765	12.756	EPSD	TCGA;ICGC;COSMIC	8.283	Down-regulation
Atypical_PIKK_DNAPK_PRKDC_ST	Q15648	MED1	P78527	PRKDC	S872	S876I	876	Missense	distal	4	no	12.765	12.692	EPSD	TCGA;ICGC	8.283	Down-regulation
Atypical_PIKK_DNAPK_PRKDC_ST	Q15648	MED1	P78527	PRKDC	S874	N871S	871	Missense	distal	-3	no	13.147	12.968	EPSD	TCGA;ICGC;COSMIC	8.283	Down-regulation
Atypical_PIKK_DNAPK_PRKDC_ST	Q15648	MED1	P78527	PRKDC	S874	S876I	876	Missense	proximal	2	no	13.147	10.284	EPSD	TCGA;ICGC	8.283	Down-regulation
Atypical_PIKK_DNAPK_PRKDC_ST	Q15648	MED1	P78527	PRKDC	S887	D891G	891	Missense	distal	4	no	12.552	12.549	EPSD	TCGA;ICGC;COSMIC	8.283	Down-regulation
Atypical_PIKK_DNAPK_PRKDC_ST	Q15648	MED1	P78527	PRKDC	S887	S889T	889	Missense	proximal	2	no	12.552	11.568	EPSD	TCGA;ICGC;COSMIC	8.283	Down-regulation
Atypical_PIKK_DNAPK_PRKDC_ST	Q15648	MED1	P78527	PRKDC	S900	Q901R	901	Missense	proximal	1	no	11.935	1.521	EPSD	TCGA;ICGC;COSMIC	8.283	Loss
Atypical_PIKK_DNAPK_PRKDC_ST	Q15648	MED1	P78527	PRKDC	S1023	H1024Y	1024	Missense	proximal	1	no	3.141	9.481	EPSD	TCGA;ICGC;COSMIC	8.283	Gain
Atypical_PIKK_DNAPK_PRKDC_ST	Q15648	MED1	P78527	PRKDC	S1042	S1049C	1049	Missense	distal	7	no	8.436	6.976	EPSD	TCGA;ICGC;COSMIC	8.283	Loss
Atypical_PIKK_DNAPK_PRKDC_ST	Q15648	MED1	P78527	PRKDC	S1049	S1049C	1049	Missense	central	0	yes	11.137	0.000	EPSD	TCGA;ICGC;COSMIC	8.283	Loss
Atypical_PIKK_DNAPK_PRKDC_ST	Q15648	MED1	P78527	PRKDC	T1051	S1049C	1049	Missense	proximal	-2	no	8.611	8.766	EPSD	TCGA;ICGC;COSMIC	8.283	Up-regulation
Atypical_PIKK_DNAPK_PRKDC_ST	Q15648	MED1	P78527	PRKDC	S1081	V1074A	1074	Missense	distal	-7	no	12.288	13.210	EPSD	TCGA;ICGC;COSMIC	8.283	Up-regulation
Atypical_PIKK_DNAPK_PRKDC_ST	Q15648	MED1	P78527	PRKDC	S1081	P1077S	1077	Missense	distal	-4	no	12.288	12.689	EPSD	TCGA;ICGC;COSMIC	8.283	Up-regulation
Atypical_PIKK_DNAPK_PRKDC_ST	Q15648	MED1	P78527	PRKDC	S1134	Q1135H	1135	Missense	proximal	1	no	13.157	2.822	EPSD	TCGA;ICGC;COSMIC	8.283	Loss
Atypical_PIKK_DNAPK_PRKDC_ST	Q15648	MED1	P78527	PRKDC	S1134	S1129G	1129	Missense	distal	-5	no	13.157	12.855	EPSD	TCGA;ICGC;COSMIC	8.283	Down-regulation
Atypical_PIKK_DNAPK_PRKDC_ST	Q15648	MED1	P78527	PRKDC	S1134	G1139E	1139	Missense	distal	5	no	13.157	13.379	EPSD	TCGA;ICGC;COSMIC	8.283	Up-regulation
Atypical_PIKK_DNAPK_PRKDC_ST	Q15648	MED1	P78527	PRKDC	S1141	Q1135H	1135	Missense	distal	-6	no	16.658	16.409	EPSD	TCGA;ICGC;COSMIC	8.283	Down-regulation
Atypical_PIKK_DNAPK_PRKDC_ST	Q15648	MED1	P78527	PRKDC	S1141	S1143C	1143	Missense	proximal	2	no	16.658	15.507	EPSD	TCGA;ICGC;COSMIC	8.283	Down-regulation
Atypical_PIKK_DNAPK_PRKDC_ST	Q15648	MED1	P78527	PRKDC	S1141	G1139E	1139	Missense	proximal	-2	no	16.658	16.542	EPSD	TCGA;ICGC;COSMIC	8.283	Down-regulation
Atypical_PIKK_DNAPK_PRKDC_ST	Q15648	MED1	P78527	PRKDC	S1147	G1154D	1154	Missense	distal	7	no	12.053	12.870	EPSD	TCGA;ICGC;COSMIC	8.283	Up-regulation
Atypical_PIKK_DNAPK_PRKDC_ST	Q15648	MED1	P78527	PRKDC	S1147	S1149F	1149	Missense	proximal	2	no	12.053	10.952	EPSD	TCGA;ICGC;COSMIC	8.283	Down-regulation
Atypical_PIKK_DNAPK_PRKDC_ST	Q15648	MED1	P78527	PRKDC	S1147	S1143C	1143	Missense	distal	-4	no	12.053	11.292	EPSD	TCGA;ICGC;COSMIC	8.283	Down-regulation
Atypical_PIKK_DNAPK_PRKDC_ST	Q15648	MED1	P78527	PRKDC	S1192	H1195Y	1195	Missense	distal	3	no	8.897	8.909	EPSD	TCGA;ICGC;COSMIC	8.283	Up-regulation
Atypical_PIKK_DNAPK_PRKDC_ST	Q15648	MED1	P78527	PRKDC	S1194	H1195Y	1195	Missense	proximal	1	no	2.016	8.356	EPSD	TCGA;ICGC;COSMIC	8.283	Gain
Atypical_PIKK_DNAPK_PRKDC_ST	Q15648	MED1	P78527	PRKDC	S1238	S1239L	1239	Missense	proximal	1	no	4.115	8.409	EPSD	TCGA;ICGC;COSMIC	8.283	Gain
Atypical_PIKK_DNAPK_PRKDC_ST	Q15648	MED1	P78527	PRKDC	S1371	S1368F	1368	Missense	distal	-3	no	8.518	8.500	EPSD	TCGA;ICGC;COSMIC	8.283	Down-regulation
Atypical_PIKK_DNAPK_PRKDC_ST	Q15648	MED1	P78527	PRKDC	T1378	S1379L	1379	Missense	proximal	1	no	4.580	8.874	EPSD	TCGA;ICGC;COSMIC	8.283	Gain
Atypical_PIKK_DNAPK_PRKDC_ST	Q15648	MED1	P78527	PRKDC	S1417	G1420W	1420	Missense	distal	3	no	8.472	8.123	EPSD	TCGA;ICGC	8.283	Loss
Atypical_PIKK_DNAPK_PRKDC_ST	Q15648	MED1	P78527	PRKDC	S1447	P1448S	1448	Missense	proximal	1	no	9.087	4.732	EPSD	TCGA;ICGC;COSMIC	8.283	Loss
Atypical_PIKK_DNAPK_PRKDC_ST	Q15648	MED1	P78527	PRKDC	S1447	P1448A	1448	Missense	proximal	1	no	9.087	8.263	EPSD	TCGA;ICGC;COSMIC	8.283	Loss
Atypical_PIKK_DNAPK_PRKDC_ST	Q15648	MED1	P78527	PRKDC	S1561	S1558L	1558	Missense	distal	-3	no	11.063	11.001	EPSD	TCGA;ICGC;COSMIC	8.283	Down-regulation
Atypical_PIKK_DNAPK_PRKDC_ST	Q15648	MED1	P78527	PRKDC	S1561	A1554S	1554	Missense	distal	-7	no	11.063	11.115	EPSD	TCGA;ICGC;COSMIC	8.283	Up-regulation
Atypical_PIKK_DNAPK_PRKDC_ST	Q15648	MED1	P78527	PRKDC	S1561	S1561I	1561	Missense	central	0	yes	11.063	0.000	EPSD	TCGA;ICGC	8.283	Loss
Atypical_PIKK_DNAPK_PRKDC_ST	P07954	FH	P78527	PRKDC	S46	S46R	46	Missense	central	0	yes	12.660	0.000	EPSD	TCGA;ICGC;COSMIC	8.283	Loss
Atypical_PIKK_DNAPK_PRKDC_ST	P07954	FH	P78527	PRKDC	S46	S49F	49	Missense	distal	3	no	12.660	12.374	EPSD	TCGA;ICGC;COSMIC	8.283	Down-regulation
Atypical_PIKK_DNAPK_PRKDC_ST	P07954	FH	P78527	PRKDC	T236	P241A	241	Missense	distal	5	no	10.566	10.620	PhosphoSitePlus	TCGA;ICGC;COSMIC	8.283	Up-regulation
Atypical_PIKK_DNAPK_PRKDC_ST	P07954	FH	P78527	PRKDC	T236	Q237K	237	Missense	proximal	1	no	10.566	-0.639	PhosphoSitePlus	TCGA;ICGC;COSMIC	8.283	Loss
Atypical_PIKK_DNAPK_PRKDC_ST	P07954	FH	P78527	PRKDC	T236	H235R	235	Missense	proximal	-1	no	10.566	9.513	PhosphoSitePlus	TCGA;ICGC;COSMIC	8.283	Down-regulation
Atypical_PIKK_DNAPK_PRKDC_ST	O43918	AIRE	P78527	PRKDC	T68	Q69H	69	Missense	proximal	1	no	14.219	3.884	PhosphoSitePlus;EPSD	TCGA;ICGC;COSMIC	8.283	Loss
Atypical_PIKK_DNAPK_PRKDC_ST	O43918	AIRE	P78527	PRKDC	S107	R110W	110	Missense	distal	3	no	12.995	12.858	EPSD	TCGA;ICGC;COSMIC	8.283	Down-regulation
Atypical_PIKK_DNAPK_PRKDC_ST	O43918	AIRE	P78527	PRKDC	S107	D103N	103	Missense	distal	-4	no	12.995	13.031	EPSD	TCGA;ICGC;COSMIC	8.283	Up-regulation
Atypical_PIKK_DNAPK_PRKDC_ST	O43918	AIRE	P78527	PRKDC	S156	G150V	150	Missense	distal	-6	no	10.677	10.259	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	8.283	Down-regulation
Atypical_PIKK_DNAPK_PRKDC_ST	O43918	AIRE	P78527	PRKDC	T232	E237K	237	Missense	distal	5	no	9.296	9.063	EPSD	TCGA;ICGC;COSMIC;GDSC;CCLE	8.283	Down-regulation
Atypical_PIKK_DNAPK_PRKDC_ST	P31270	HOXA11	P78527	PRKDC	S98	Q95H	95	Missense	distal	-3	no	9.115	8.986	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	8.283	Down-regulation
Atypical_PIKK_DNAPK_PRKDC_ST	P31270	HOXA11	P78527	PRKDC	S98	A99V	99	Missense	proximal	1	no	9.115	8.379	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	8.283	Down-regulation
Atypical_PIKK_DNAPK_PRKDC_ST	P11831	SRF	P78527	PRKDC	S224	T217I	217	Missense	distal	-7	no	9.633	8.397	EPSD	TCGA;COSMIC	8.283	Down-regulation
Atypical_PIKK_DNAPK_PRKDC_ST	P11831	SRF	P78527	PRKDC	S224	D229N	229	Missense	distal	5	no	9.633	9.483	EPSD	TCGA;COSMIC	8.283	Down-regulation
Atypical_PIKK_DNAPK_PRKDC_ST	P11831	SRF	P78527	PRKDC	S446	V443A	443	Missense	distal	-3	no	13.011	13.194	PhosphoSitePlus;EPSD	TCGA;COSMIC	8.283	Up-regulation
Atypical_PIKK_DNAPK_PRKDC_ST	P31749	AKT1	P78527	PRKDC	S124	R121W	121	Missense	distal	-3	no	10.030	9.888	EPSD	TCGA;ICGC;COSMIC	8.283	Down-regulation
Atypical_PIKK_DNAPK_PRKDC_ST	P31749	AKT1	P78527	PRKDC	S124	A131T	131	Missense	distal	7	no	10.030	9.414	EPSD	TCGA;ICGC;COSMIC	8.283	Down-regulation
Atypical_PIKK_DNAPK_PRKDC_ST	P31749	AKT1	P78527	PRKDC	T211	T211I	211	Missense	central	0	yes	8.453	0.000	EPSD	TCGA;ICGC;COSMIC	8.283	Loss
Atypical_PIKK_DNAPK_PRKDC_ST	P31749	AKT1	P78527	PRKDC	T312	G311D	311	Missense	proximal	-1	no	9.481	10.494	EPSD	TCGA;ICGC;COSMIC;GDSC;CCLE	8.283	Up-regulation
Atypical_PIKK_DNAPK_PRKDC_ST	P31749	AKT1	P78527	PRKDC	S422	Y417C	417	Missense	distal	-5	no	8.605	8.493	EPSD	TCGA;ICGC;COSMIC	8.283	Down-regulation
Atypical_PIKK_DNAPK_PRKDC_ST	P31749	AKT1	P78527	PRKDC	S422	P423T	423	Missense	proximal	1	no	8.605	2.540	EPSD	TCGA;ICGC	8.283	Loss
Atypical_PIKK_DNAPK_PRKDC_ST	P31749	AKT1	P78527	PRKDC	S422	E418K	418	Missense	distal	-4	no	8.605	8.348	EPSD	TCGA;ICGC	8.283	Down-regulation
Atypical_PIKK_DNAPK_PRKDC_ST	P31749	AKT1	P78527	PRKDC	S473	S475L	475	Missense	proximal	2	no	9.351	8.163	PhosphoSitePlus	TCGA;ICGC;COSMIC	8.283	Loss
Atypical_PIKK_DNAPK_PRKDC_ST	O96017	CHEK2	P78527	PRKDC	S19	S24C	24	Missense	distal	5	no	13.226	13.026	EPSD	TCGA;ICGC;COSMIC	8.283	Down-regulation
Atypical_PIKK_DNAPK_PRKDC_ST	O96017	CHEK2	P78527	PRKDC	S19	C18S	18	Missense	proximal	-1	no	13.226	13.907	EPSD	TCGA;ICGC;COSMIC	8.283	Up-regulation
Atypical_PIKK_DNAPK_PRKDC_ST	O96017	CHEK2	P78527	PRKDC	S19	S16R	16	Missense	distal	-3	no	13.226	12.974	EPSD	TCGA;ICGC;COSMIC	8.283	Down-regulation
Atypical_PIKK_DNAPK_PRKDC_ST	O96017	CHEK2	P78527	PRKDC	S24	S24C	24	Missense	central	0	yes	8.931	0.000	EPSD	TCGA;ICGC;COSMIC	8.283	Loss
Atypical_PIKK_DNAPK_PRKDC_ST	O96017	CHEK2	P78527	PRKDC	S24	C18S	18	Missense	distal	-6	no	8.931	9.789	EPSD	TCGA;ICGC;COSMIC	8.283	Up-regulation
Atypical_PIKK_DNAPK_PRKDC_ST	O96017	CHEK2	P78527	PRKDC	T26	S24C	24	Missense	proximal	-2	no	13.876	14.031	EPSD	TCGA;ICGC;COSMIC	8.283	Up-regulation
Atypical_PIKK_DNAPK_PRKDC_ST	O96017	CHEK2	P78527	PRKDC	S28	S24C	24	Missense	distal	-4	no	12.733	11.971	EPSD	TCGA;ICGC;COSMIC	8.283	Down-regulation
Atypical_PIKK_DNAPK_PRKDC_ST	O96017	CHEK2	P78527	PRKDC	S35	S42C	42	Missense	distal	7	no	14.547	13.087	EPSD	TCGA;ICGC;COSMIC	8.283	Down-regulation
Atypical_PIKK_DNAPK_PRKDC_ST	O96017	CHEK2	P78527	PRKDC	S50	S53F	53	Missense	distal	3	no	15.189	14.903	EPSD	TCGA;ICGC;COSMIC	8.283	Down-regulation
Atypical_PIKK_DNAPK_PRKDC_ST	O96017	CHEK2	P78527	PRKDC	S50	S56R	56	Missense	distal	6	no	15.189	15.169	EPSD	TCGA;ICGC;COSMIC	8.283	Down-regulation
Atypical_PIKK_DNAPK_PRKDC_ST	O96017	CHEK2	P78527	PRKDC	S62	S56R	56	Missense	distal	-6	no	9.154	8.650	EPSD	TCGA;ICGC;COSMIC	8.283	Down-regulation
Atypical_PIKK_DNAPK_PRKDC_ST	O96017	CHEK2	P78527	PRKDC	T68	E70G	70	Missense	proximal	2	no	13.763	12.354	PhosphoSitePlus;EPSD	TCGA	8.283	Down-regulation
Atypical_PIKK_DNAPK_PRKDC_ST	O96017	CHEK2	P78527	PRKDC	S357	E351Q	351	Missense	distal	-6	no	11.047	11.112	EPSD	TCGA;COSMIC	8.283	Up-regulation
Atypical_PIKK_DNAPK_PRKDC_ST	O96017	CHEK2	P78527	PRKDC	T387	E394D	394	Missense	distal	7	no	9.198	9.288	EPSD;PhosphoSitePlus	TCGA;COSMIC	8.283	Up-regulation
Atypical_PIKK_DNAPK_PRKDC_ST	P42575	CASP2	P78527	PRKDC	S164	P171H	171	Missense	distal	7	no	11.019	11.170	EPSD	TCGA;ICGC	8.283	Up-regulation
Atypical_PIKK_DNAPK_PRKDC_ST	P42575	CASP2	P78527	PRKDC	S164	S164F	164	Missense	central	0	yes	11.019	0.000	EPSD	TCGA;ICGC;COSMIC	8.283	Loss
Atypical_PIKK_DNAPK_PRKDC_ST	P42575	CASP2	P78527	PRKDC	S164	S157L	157	Missense	distal	-7	no	11.019	10.552	EPSD	TCGA;ICGC	8.283	Down-regulation
Atypical_PIKK_DNAPK_PRKDC_ST	P42575	CASP2	P78527	PRKDC	S340	D347N	347	Missense	distal	7	no	8.405	7.739	EPSD	TCGA;ICGC;COSMIC	8.283	Loss
Atypical_PIKK_DNAPK_PRKDC_ST	Q9BQ15	NABP2	P78527	PRKDC	T117	A124V	124	Missense	distal	7	no	13.888	12.798	EPSD	TCGA;ICGC;COSMIC;GDSC	8.283	Down-regulation
Atypical_PIKK_DNAPK_PRKDC_ST	Q9BQ15	NABP2	P78527	PRKDC	S134	S132L	132	Missense	proximal	-2	no	14.123	14.146	PhosphoSitePlus	TCGA;ICGC;COSMIC	8.283	Up-regulation
Atypical_PIKK_DNAPK_PRKDC_ST	Q9BQ15	NABP2	P78527	PRKDC	S134	T138A	138	Missense	distal	4	no	14.123	14.184	PhosphoSitePlus	TCGA;ICGC;COSMIC	8.283	Up-regulation
Atypical_PIKK_DNAPK_PRKDC_ST	Q9BQ15	NABP2	P78527	PRKDC	S134	Q135R	135	Missense	proximal	1	no	14.123	3.709	PhosphoSitePlus	TCGA;ICGC	8.283	Loss
Atypical_PIKK_DNAPK_PRKDC_ST	Q9BQ15	NABP2	P78527	PRKDC	S141	T138A	138	Missense	distal	-3	no	8.297	8.358	EPSD	TCGA;ICGC;COSMIC	8.283	Up-regulation
Atypical_PIKK_DNAPK_PRKDC_ST	Q9BQ15	NABP2	P78527	PRKDC	S141	Q135R	135	Missense	distal	-6	no	8.297	7.689	EPSD	TCGA;ICGC	8.283	Loss
Atypical_PIKK_DNAPK_PRKDC_ST	Q9BQ15	NABP2	P78527	PRKDC	S144	T138A	138	Missense	distal	-6	no	7.979	8.370	EPSD	TCGA;ICGC;COSMIC	8.283	Gain
Atypical_PIKK_DNAPK_PRKDC_ST	P49917	LIG4	P78527	PRKDC	S199	L194V	194	Missense	distal	-5	no	11.243	10.973	EPSD	TCGA;COSMIC;CCLE	8.283	Down-regulation
Atypical_PIKK_DNAPK_PRKDC_ST	P49917	LIG4	P78527	PRKDC	T788	N783K	783	Missense	distal	-5	no	9.154	9.275	EPSD	TCGA;ICGC	8.283	Up-regulation
Atypical_PIKK_DNAPK_PRKDC_ST	P49917	LIG4	P78527	PRKDC	T788	N783H	783	Missense	distal	-5	no	9.154	9.289	EPSD	TCGA;ICGC;COSMIC	8.283	Up-regulation
Atypical_PIKK_DNAPK_PRKDC_ST	P08670	VIM	P78527	PRKDC	S10	S8L	8	Missense	proximal	-2	no	9.148	9.171	EPSD	TCGA;ICGC;COSMIC	8.283	Up-regulation
Atypical_PIKK_DNAPK_PRKDC_ST	P08670	VIM	P78527	PRKDC	S10	F15L	15	Missense	distal	5	no	9.148	9.117	EPSD	TCGA;ICGC;COSMIC	8.283	Down-regulation
Atypical_PIKK_DNAPK_PRKDC_ST	P08670	VIM	P78527	PRKDC	S10	F15V	15	Missense	distal	5	no	9.148	9.037	EPSD	TCGA;ICGC	8.283	Down-regulation
Atypical_PIKK_DNAPK_PRKDC_ST	P08670	VIM	P78527	PRKDC	S51	R50H	50	Missense	proximal	-1	no	7.862	8.915	EPSD	TCGA;ICGC;COSMIC	8.283	Gain
Atypical_PIKK_DNAPK_PRKDC_ST	P08670	VIM	P78527	PRKDC	S56	R50H	50	Missense	distal	-6	no	9.041	9.401	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	8.283	Up-regulation
Atypical_PIKK_DNAPK_PRKDC_ST	P08670	VIM	P78527	PRKDC	S56	P57L	57	Missense	proximal	1	no	9.041	8.980	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC;CCLE	8.283	Down-regulation
Atypical_PIKK_DNAPK_PRKDC_ST	P08670	VIM	P78527	PRKDC	S56	P57R	57	Missense	proximal	1	no	9.041	3.107	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	8.283	Loss
Atypical_PIKK_DNAPK_PRKDC_ST	P08670	VIM	P78527	PRKDC	T202	Q195H	195	Missense	distal	-7	no	9.911	9.914	EPSD	TCGA;ICGC;COSMIC	8.283	Up-regulation
Atypical_PIKK_DNAPK_PRKDC_ST	P08670	VIM	P78527	PRKDC	S214	R217H	217	Missense	distal	3	no	10.423	10.729	EPSD	TCGA;ICGC;COSMIC	8.283	Up-regulation
Atypical_PIKK_DNAPK_PRKDC_ST	P08670	VIM	P78527	PRKDC	S214	E221K	221	Missense	distal	7	no	10.423	9.610	EPSD	TCGA;ICGC;COSMIC	8.283	Down-regulation
Atypical_PIKK_DNAPK_PRKDC_ST	P08670	VIM	P78527	PRKDC	S214	E221Q	221	Missense	distal	7	no	10.423	10.518	EPSD	TCGA;ICGC;COSMIC	8.283	Up-regulation
Atypical_PIKK_DNAPK_PRKDC_ST	P08670	VIM	P78527	PRKDC	S214	D211H	211	Missense	distal	-3	no	10.423	10.556	EPSD	TCGA;ICGC;COSMIC	8.283	Up-regulation
Atypical_PIKK_DNAPK_PRKDC_ST	P08670	VIM	P78527	PRKDC	S214	R217C	217	Missense	distal	3	no	10.423	10.534	EPSD	TCGA;ICGC;COSMIC	8.283	Up-regulation
Atypical_PIKK_DNAPK_PRKDC_ST	P08670	VIM	P78527	PRKDC	S214	L215V	215	Missense	proximal	1	no	10.423	8.924	EPSD	TCGA;ICGC;COSMIC	8.283	Down-regulation
Atypical_PIKK_DNAPK_PRKDC_ST	P08670	VIM	P78527	PRKDC	S278	S278R	278	Missense	central	0	yes	8.729	0.000	EPSD	TCGA;ICGC;COSMIC	8.283	Loss
Atypical_PIKK_DNAPK_PRKDC_ST	P08670	VIM	P78527	PRKDC	S278	N283D	283	Missense	distal	5	no	8.729	8.879	EPSD	TCGA;ICGC;COSMIC	8.283	Up-regulation
Atypical_PIKK_DNAPK_PRKDC_ST	P08670	VIM	P78527	PRKDC	S339	L340M	340	Missense	proximal	1	no	10.022	2.751	EPSD	TCGA;ICGC;COSMIC	8.283	Loss
Atypical_PIKK_DNAPK_PRKDC_ST	P08670	VIM	P78527	PRKDC	S339	A332S	332	Missense	distal	-7	no	10.022	10.074	EPSD	TCGA;ICGC;COSMIC	8.283	Up-regulation
Atypical_PIKK_DNAPK_PRKDC_ST	P08670	VIM	P78527	PRKDC	S339	S339F	339	Missense	central	0	yes	10.022	0.000	EPSD	TCGA;ICGC;COSMIC	8.283	Loss
Atypical_PIKK_DNAPK_PRKDC_ST	P08670	VIM	P78527	PRKDC	S339	R345H	345	Missense	distal	6	no	10.022	10.048	EPSD	TCGA;ICGC;COSMIC	8.283	Up-regulation
Atypical_PIKK_DNAPK_PRKDC_ST	P08670	VIM	P78527	PRKDC	S339	R345C	345	Missense	distal	6	no	10.022	10.029	EPSD	TCGA;ICGC;COSMIC	8.283	Up-regulation
Atypical_PIKK_DNAPK_PRKDC_ST	P08670	VIM	P78527	PRKDC	S412	E407K	407	Missense	distal	-5	no	8.758	8.706	EPSD	TCGA;ICGC;COSMIC	8.283	Down-regulation
Atypical_PIKK_DNAPK_PRKDC_ST	P08670	VIM	P78527	PRKDC	S412	E407V	407	Missense	distal	-5	no	8.758	8.111	EPSD	TCGA;ICGC	8.283	Loss
Atypical_PIKK_DNAPK_PRKDC_ST	P08670	VIM	P78527	PRKDC	S412	E407D	407	Missense	distal	-5	no	8.758	8.575	EPSD	TCGA;ICGC;COSMIC	8.283	Down-regulation
Atypical_PIKK_DNAPK_PRKDC_ST	P08670	VIM	P78527	PRKDC	S420	L421P	421	Missense	proximal	1	no	8.270	8.331	EPSD	TCGA;ICGC;COSMIC	8.283	Gain
Atypical_PIKK_DNAPK_PRKDC_ST	P08670	VIM	P78527	PRKDC	S430	R424W	424	Missense	distal	-6	no	11.345	10.858	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	8.283	Down-regulation
Atypical_PIKK_DNAPK_PRKDC_ST	P08670	VIM	P78527	PRKDC	S430	D429Y	429	Missense	proximal	-1	no	11.345	10.933	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	8.283	Down-regulation
Atypical_PIKK_DNAPK_PRKDC_ST	P08670	VIM	P78527	PRKDC	S430	P432L	432	Missense	proximal	2	no	11.345	10.387	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	8.283	Down-regulation
Atypical_PIKK_DNAPK_PRKDC_ST	P08670	VIM	P78527	PRKDC	S430	V434A	434	Missense	distal	4	no	11.345	11.412	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	8.283	Up-regulation
Atypical_PIKK_DNAPK_PRKDC_ST	P08670	VIM	P78527	PRKDC	S459	E457K	457	Missense	proximal	-2	no	12.148	12.238	PhosphoSitePlus;EPSD	TCGA;ICGC;COSMIC;CCLE	8.283	Up-regulation
Atypical_PIKK_DNAPK_PRKDC_ST	P18887	XRCC1	P78527	PRKDC	S14	T18A	18	Missense	distal	4	no	13.569	13.629	EPSD	TCGA;ICGC;COSMIC	8.283	Up-regulation
Atypical_PIKK_DNAPK_PRKDC_ST	P18887	XRCC1	P78527	PRKDC	S14	C12R	12	Missense	proximal	-2	no	13.569	13.540	EPSD	TCGA;ICGC;COSMIC	8.283	Down-regulation
Atypical_PIKK_DNAPK_PRKDC_ST	P18887	XRCC1	P78527	PRKDC	S17	T18A	18	Missense	proximal	1	no	3.283	8.524	EPSD	TCGA;ICGC;COSMIC	8.283	Gain
Atypical_PIKK_DNAPK_PRKDC_ST	P18887	XRCC1	P78527	PRKDC	S151	H150Y	150	Missense	proximal	-1	no	9.442	9.469	EPSD	TCGA;ICGC;COSMIC	8.283	Up-regulation
Atypical_PIKK_DNAPK_PRKDC_ST	P18887	XRCC1	P78527	PRKDC	S181	R174S	174	Missense	distal	-7	no	7.868	8.534	EPSD	TCGA;ICGC;COSMIC	8.283	Gain
Atypical_PIKK_DNAPK_PRKDC_ST	P18887	XRCC1	P78527	PRKDC	S241	P242L	242	Missense	proximal	1	no	8.463	8.402	EPSD	TCGA;ICGC;COSMIC	8.283	Down-regulation
Atypical_PIKK_DNAPK_PRKDC_ST	P18887	XRCC1	P78527	PRKDC	T453	K458E	458	Missense	distal	5	no	11.500	11.733	EPSD	TCGA;ICGC;COSMIC	8.283	Up-regulation
Atypical_PIKK_DNAPK_PRKDC_ST	P18887	XRCC1	P78527	PRKDC	T519	T519M	519	Missense	central	0	yes	8.365	0.000	EPSD	TCGA;ICGC;COSMIC	8.283	Loss
Atypical_PIKK_DNAPK_PRKDC_ST	P18887	XRCC1	P78527	PRKDC	T519	T523M	523	Missense	distal	4	no	8.365	8.377	EPSD	TCGA;ICGC;COSMIC	8.283	Up-regulation
Atypical_PIKK_DNAPK_PRKDC_ST	Q9NUW8	TDP1	P78527	PRKDC	S2	D6N	6	Missense	distal	4	no	11.882	11.905	EPSD	TCGA;ICGC;COSMIC	8.283	Up-regulation
Atypical_PIKK_DNAPK_PRKDC_ST	Q9NUW8	TDP1	P78527	PRKDC	S18	E21Q	21	Missense	distal	3	no	8.473	8.375	EPSD	TCGA;ICGC;COSMIC	8.283	Down-regulation
Atypical_PIKK_DNAPK_PRKDC_ST	Q9NUW8	TDP1	P78527	PRKDC	S18	E20G	20	Missense	proximal	2	no	8.473	7.065	EPSD	TCGA;ICGC;COSMIC	8.283	Loss
Atypical_PIKK_DNAPK_PRKDC_ST	Q9NUW8	TDP1	P78527	PRKDC	S81	G80C	80	Missense	proximal	-1	no	13.261	12.842	PhosphoSitePlus	TCGA;ICGC;COSMIC	8.283	Down-regulation
Atypical_PIKK_DNAPK_PRKDC_ST	Q9NUW8	TDP1	P78527	PRKDC	S81	G80V	80	Missense	proximal	-1	no	13.261	12.622	PhosphoSitePlus	TCGA;ICGC;COSMIC	8.283	Down-regulation
Atypical_PIKK_DNAPK_PRKDC_ST	Q9NUW8	TDP1	P78527	PRKDC	S81	S81F	81	Missense	central	0	yes	13.261	0.000	PhosphoSitePlus	TCGA;ICGC;COSMIC	8.283	Loss
Atypical_PIKK_DNAPK_PRKDC_ST	Q9NUW8	TDP1	P78527	PRKDC	S434	P430L	430	Missense	distal	-4	no	9.107	9.063	EPSD	TCGA;ICGC	8.283	Down-regulation
Atypical_PIKK_DNAPK_PRKDC_ST	Q9NUW8	TDP1	P78527	PRKDC	T466	P461L	461	Missense	distal	-5	no	9.873	9.886	EPSD	TCGA;ICGC;COSMIC	8.283	Up-regulation
Atypical_PIKK_DNAPK_PRKDC_ST	Q9NUW8	TDP1	P78527	PRKDC	T466	Q465P	465	Missense	proximal	-1	no	9.873	9.423	EPSD	TCGA;ICGC	8.283	Down-regulation
Atypical_PIKK_DNAPK_PRKDC_ST	Q9NUW8	TDP1	P78527	PRKDC	S563	A568G	568	Missense	distal	5	no	13.591	13.453	EPSD	TCGA;ICGC;COSMIC	8.283	Down-regulation
Atypical_PIKK_DNAPK_PRKDC_ST	Q9NUW8	TDP1	P78527	PRKDC	S563	K558T	558	Missense	distal	-5	no	13.591	13.382	EPSD	TCGA;ICGC;COSMIC	8.283	Down-regulation
Atypical_PIKK_DNAPK_PRKDC_ST	Q8IZL8	PELP1	P78527	PRKDC	S7	S13C	13	Missense	distal	6	no	8.492	8.479	EPSD	TCGA;ICGC;COSMIC	8.283	Down-regulation
Atypical_PIKK_DNAPK_PRKDC_ST	Q8IZL8	PELP1	P78527	PRKDC	S10	S13C	13	Missense	distal	3	no	10.189	9.828	EPSD	TCGA;ICGC;COSMIC	8.283	Down-regulation
Atypical_PIKK_DNAPK_PRKDC_ST	Q8IZL8	PELP1	P78527	PRKDC	S10	S13A	13	Missense	distal	3	no	10.189	10.124	EPSD	TCGA;ICGC;COSMIC	8.283	Down-regulation
Atypical_PIKK_DNAPK_PRKDC_ST	Q8IZL8	PELP1	P78527	PRKDC	S13	S13C	13	Missense	central	0	yes	8.997	0.000	EPSD	TCGA;ICGC;COSMIC	8.283	Loss
Atypical_PIKK_DNAPK_PRKDC_ST	Q8IZL8	PELP1	P78527	PRKDC	S13	S13A	13	Missense	central	0	yes	8.997	0.000	EPSD	TCGA;ICGC;COSMIC	8.283	Loss
Atypical_PIKK_DNAPK_PRKDC_ST	Q8IZL8	PELP1	P78527	PRKDC	S251	E258K	258	Missense	distal	7	no	13.258	12.445	EPSD	TCGA;ICGC;COSMIC	8.283	Down-regulation
Atypical_PIKK_DNAPK_PRKDC_ST	Q8IZL8	PELP1	P78527	PRKDC	S485	G484W	484	Missense	proximal	-1	no	9.993	9.163	EPSD	TCGA;COSMIC	8.283	Down-regulation
Atypical_PIKK_DNAPK_PRKDC_ST	Q8IZL8	PELP1	P78527	PRKDC	S485	G480E	480	Missense	distal	-5	no	9.993	10.314	EPSD	TCGA;COSMIC	8.283	Up-regulation
Atypical_PIKK_DNAPK_PRKDC_ST	Q8IZL8	PELP1	P78527	PRKDC	S485	G480R	480	Missense	distal	-5	no	9.993	9.822	EPSD	TCGA;COSMIC	8.283	Down-regulation
Atypical_PIKK_DNAPK_PRKDC_ST	Q8IZL8	PELP1	P78527	PRKDC	S485	P478S	478	Missense	distal	-7	no	9.993	10.643	EPSD	TCGA;COSMIC	8.283	Up-regulation
Atypical_PIKK_DNAPK_PRKDC_ST	Q8IZL8	PELP1	P78527	PRKDC	S492	A493V	493	Missense	proximal	1	no	8.975	8.240	EPSD	TCGA;COSMIC	8.283	Loss
Atypical_PIKK_DNAPK_PRKDC_ST	Q8IZL8	PELP1	P78527	PRKDC	S492	P494A	494	Missense	proximal	2	no	8.975	9.178	EPSD	TCGA;COSMIC	8.283	Up-regulation
Atypical_PIKK_DNAPK_PRKDC_ST	Q8IZL8	PELP1	P78527	PRKDC	S492	A493T	493	Missense	proximal	1	no	8.975	3.734	EPSD	TCGA;COSMIC	8.283	Loss
Atypical_PIKK_DNAPK_PRKDC_ST	Q8IZL8	PELP1	P78527	PRKDC	T647	P650L	650	Missense	distal	3	no	9.452	9.117	EPSD	TCGA;COSMIC	8.283	Down-regulation
Atypical_PIKK_DNAPK_PRKDC_ST	Q8IZL8	PELP1	P78527	PRKDC	T647	P653S	653	Missense	distal	6	no	9.452	9.443	EPSD	TCGA;COSMIC	8.283	Down-regulation
Atypical_PIKK_DNAPK_PRKDC_ST	Q8IZL8	PELP1	P78527	PRKDC	S991	P997S	997	Missense	distal	6	no	10.083	10.074	EPSD	TCGA;COSMIC;CCLE	8.283	Down-regulation
Atypical_PIKK_DNAPK_PRKDC_ST	Q8IZL8	PELP1	P78527	PRKDC	S991	P992L	992	Missense	proximal	1	no	10.083	10.022	EPSD	TCGA;COSMIC	8.283	Down-regulation
Atypical_PIKK_DNAPK_PRKDC_ST	Q8IZL8	PELP1	P78527	PRKDC	S991	E990V	990	Missense	proximal	-1	no	10.083	8.177	EPSD	TCGA;COSMIC	8.283	Loss
Atypical_PIKK_DNAPK_PRKDC_ST	Q8IZL8	PELP1	P78527	PRKDC	T1022	L1026M	1026	Missense	distal	4	no	8.535	8.525	EPSD	TCGA	8.283	Down-regulation
Atypical_PIKK_DNAPK_PRKDC_ST	Q8IZL8	PELP1	P78527	PRKDC	T1022	P1024S	1024	Missense	proximal	2	no	8.535	8.766	EPSD	TCGA;COSMIC	8.283	Up-regulation
Atypical_PIKK_DNAPK_PRKDC_ST	Q8IZL8	PELP1	P78527	PRKDC	T1022	A1023D	1023	Missense	proximal	1	no	8.535	7.384	EPSD	TCGA;COSMIC	8.283	Loss
Atypical_PIKK_DNAPK_PRKDC_ST	Q8IZL8	PELP1	P78527	PRKDC	T1025	L1026M	1026	Missense	proximal	1	no	8.851	1.580	EPSD	TCGA	8.283	Loss
Atypical_PIKK_DNAPK_PRKDC_ST	Q8IZL8	PELP1	P78527	PRKDC	T1025	P1024S	1024	Missense	proximal	-1	no	8.851	8.511	EPSD	TCGA;COSMIC	8.283	Down-regulation
Atypical_PIKK_DNAPK_PRKDC_ST	Q8IZL8	PELP1	P78527	PRKDC	T1025	A1023D	1023	Missense	proximal	-2	no	8.851	8.816	EPSD	TCGA;COSMIC	8.283	Down-regulation
Atypical_PIKK_DNAPK_PRKDC_ST	Q8IZL8	PELP1	P78527	PRKDC	S1033	E1038D	1038	Missense	distal	5	no	14.530	14.499	PhosphoSitePlus	TCGA;COSMIC	8.283	Down-regulation
Atypical_PIKK_DNAPK_PRKDC_ST	Q8IZL8	PELP1	P78527	PRKDC	S1033	L1026M	1026	Missense	distal	-7	no	14.530	14.351	PhosphoSitePlus	TCGA	8.283	Down-regulation
Atypical_PIKK_DNAPK_PRKDC_ST	Q8IZL8	PELP1	P78527	PRKDC	T1069	E1070Q	1070	Missense	proximal	1	no	2.635	10.370	EPSD	TCGA;COSMIC	8.283	Gain
Atypical_PIKK_DNAPK_PRKDC_ST	Q8IZL8	PELP1	P78527	PRKDC	T1082	Q1077H	1077	Missense	distal	-5	no	9.032	9.051	EPSD	TCGA	8.283	Up-regulation
Atypical_PIKK_DNAPK_PRKDC_ST	Q8IZL8	PELP1	P78527	PRKDC	T1082	P1083L	1083	Missense	proximal	1	no	9.032	8.971	EPSD	TCGA;COSMIC	8.283	Down-regulation
Atypical_PIKK_DNAPK_PRKDC_ST	P22415	USF1	P78527	PRKDC	S174	R176C	176	Missense	proximal	2	no	10.449	10.574	EPSD	TCGA;COSMIC	8.283	Up-regulation
Atypical_PIKK_DNAPK_PRKDC_ST	P22415	USF1	P78527	PRKDC	S174	R176H	176	Missense	proximal	2	no	10.449	11.344	EPSD	TCGA;COSMIC	8.283	Up-regulation
Atypical_PIKK_DNAPK_PRKDC_ST	P55895	RAG2	P78527	PRKDC	S20	F24L	24	Missense	distal	4	no	9.161	9.167	EPSD	TCGA;ICGC	8.283	Up-regulation
Atypical_PIKK_DNAPK_PRKDC_ST	P55895	RAG2	P78527	PRKDC	S365	T361I	361	Missense	distal	-4	no	13.045	12.427	PhosphoSitePlus	TCGA;ICGC;COSMIC	8.283	Down-regulation
Atypical_PIKK_DNAPK_PRKDC_ST	P55895	RAG2	P78527	PRKDC	S365	N364K	364	Missense	proximal	-1	no	13.045	12.446	PhosphoSitePlus	TCGA;ICGC;COSMIC	8.283	Down-regulation
Atypical_PIKK_DNAPK_PRKDC_ST	P55895	RAG2	P78527	PRKDC	S365	Q359H	359	Missense	distal	-6	no	13.045	12.797	PhosphoSitePlus	TCGA;ICGC;COSMIC	8.283	Down-regulation
Atypical_PIKK_DNAPK_PRKDC_ST	P55895	RAG2	P78527	PRKDC	S365	S368L	368	Missense	distal	3	no	13.045	12.664	PhosphoSitePlus	TCGA;ICGC;COSMIC	8.283	Down-regulation
Atypical_PIKK_DNAPK_PRKDC_ST	P55072	VCP	P78527	PRKDC	S3	G9V	9	Missense	distal	6	no	8.368	8.364	EPSD	TCGA;ICGC;COSMIC	8.283	Down-regulation
Atypical_PIKK_DNAPK_PRKDC_ST	P55072	VCP	P78527	PRKDC	S37	E30K	30	Missense	distal	-7	no	9.759	9.505	EPSD	TCGA;ICGC;COSMIC	8.283	Down-regulation
Atypical_PIKK_DNAPK_PRKDC_ST	P55072	VCP	P78527	PRKDC	S326	S326L	326	Missense	central	0	yes	9.446	0.000	EPSD	TCGA;ICGC;COSMIC	8.283	Loss
Atypical_PIKK_DNAPK_PRKDC_ST	P55072	VCP	P78527	PRKDC	S326	R323H	323	Missense	distal	-3	no	9.446	9.841	EPSD	TCGA;ICGC;COSMIC;GDSC;CCLE	8.283	Up-regulation
Atypical_PIKK_DNAPK_PRKDC_ST	P55072	VCP	P78527	PRKDC	S457	R453Q	453	Missense	distal	-4	no	13.546	14.244	EPSD	TCGA;ICGC;COSMIC	8.283	Up-regulation
Atypical_PIKK_DNAPK_PRKDC_ST	P55072	VCP	P78527	PRKDC	S459	R453Q	453	Missense	distal	-6	no	8.674	9.283	EPSD	TCGA;ICGC;COSMIC	8.283	Up-regulation
Atypical_PIKK_DNAPK_PRKDC_ST	P52945	PDX1	P78527	PRKDC	T11	Y7H	7	Missense	distal	-4	no	13.990	14.112	PhosphoSitePlus	TCGA	8.283	Up-regulation
Atypical_PIKK_DNAPK_PRKDC_ST	P52945	PDX1	P78527	PRKDC	T11	Q6K	6	Missense	distal	-5	no	13.990	13.996	PhosphoSitePlus	TCGA;ICGC;COSMIC	8.283	Up-regulation
Atypical_PIKK_DNAPK_PRKDC_ST	Q8TCS8	PNPT1	P78527	PRKDC	S93	S93F	93	Missense	central	0	yes	10.215	0.000	EPSD	TCGA;ICGC;COSMIC	8.283	Loss
Atypical_PIKK_DNAPK_PRKDC_ST	Q8TCS8	PNPT1	P78527	PRKDC	S280	S280L	280	Missense	central	0	yes	9.559	0.000	EPSD	TCGA;ICGC;COSMIC	8.283	Loss
Atypical_PIKK_DNAPK_PRKDC_ST	Q8TCS8	PNPT1	P78527	PRKDC	S339	Y334S	334	Missense	distal	-5	no	9.342	9.688	EPSD	TCGA;ICGC;COSMIC	8.283	Up-regulation
Atypical_PIKK_DNAPK_PRKDC_ST	Q8TCS8	PNPT1	P78527	PRKDC	S339	F340L	340	Missense	proximal	1	no	9.342	11.658	EPSD	TCGA;ICGC;COSMIC	8.283	Up-regulation
Atypical_PIKK_DNAPK_PRKDC_ST	Q8TCS8	PNPT1	P78527	PRKDC	S754	R749Q	749	Missense	distal	-5	no	7.868	8.302	EPSD	TCGA;ICGC;COSMIC	8.283	Gain
Atypical_PIKK_DNAPK_PRKDC_ST	Q8TCS8	PNPT1	P78527	PRKDC	S776	Q777R	777	Missense	proximal	1	no	11.541	1.127	PhosphoSitePlus	TCGA;ICGC	8.283	Loss
Atypical_PIKK_DNAPK_PRKDC_ST	Q8TCS8	PNPT1	P78527	PRKDC	S782	Q777R	777	Missense	distal	-5	no	10.337	9.904	EPSD	TCGA;ICGC	8.283	Down-regulation
Atypical_PIKK_DNAPK_PRKDC_ST	P11387	TOP1	P78527	PRKDC	S10	E13K	13	Missense	distal	3	no	13.022	12.464	PhosphoSitePlus	TCGA;ICGC;COSMIC	8.283	Down-regulation
Atypical_PIKK_DNAPK_PRKDC_ST	P11387	TOP1	P78527	PRKDC	S112	Q115H	115	Missense	distal	3	no	11.151	10.843	EPSD	TCGA;ICGC;COSMIC	8.283	Down-regulation
Atypical_PIKK_DNAPK_PRKDC_ST	P11387	TOP1	P78527	PRKDC	S112	F110L	110	Missense	proximal	-2	no	11.151	11.129	EPSD	TCGA;ICGC;COSMIC	8.283	Down-regulation
Atypical_PIKK_DNAPK_PRKDC_ST	P11387	TOP1	P78527	PRKDC	T303	D301H	301	Missense	proximal	-2	no	11.969	12.009	EPSD	TCGA;ICGC;COSMIC	8.283	Up-regulation
Atypical_PIKK_DNAPK_PRKDC_ST	P11387	TOP1	P78527	PRKDC	S433	R434Q	434	Missense	proximal	1	no	1.580	11.995	EPSD	TCGA;ICGC;COSMIC;GDSC	8.283	Gain
TKL_MLK_LZK_MAP3K12_ST	O14950	MYL12B	Q12852	MAP3K12	T19	R17C	17	Missense	proximal	-2	no	4.536	4.388	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	1.313	Down-regulation
TKL_MLK_LZK_MAP3K12_ST	O14950	MYL12B	Q12852	MAP3K12	S20	R17C	17	Missense	distal	-3	no	4.000	3.949	PhosphoSitePlus;EPSD	TCGA;ICGC;COSMIC	1.313	Down-regulation
TKL_MLK_LZK_MAP3K12_ST	O14950	MYL12B	Q12852	MAP3K12	T129	D136Y	136	Missense	distal	7	no	1.656	1.408	EPSD	TCGA;ICGC;COSMIC	1.313	Down-regulation
TKL_MLK_LZK_MAP3K12_ST	O14950	MYL12B	Q12852	MAP3K12	T129	F134L	134	Missense	distal	5	no	1.656	1.601	EPSD	TCGA;ICGC;COSMIC	1.313	Down-regulation
TKL_MLK_LZK_MAP3K12_ST	O14950	MYL12B	Q12852	MAP3K12	T129	L127P	127	Missense	proximal	-2	no	1.656	1.574	EPSD	TCGA;ICGC;COSMIC	1.313	Down-regulation
AGC_PKN_PKN1_ST	P10636	MAPT	Q16512	PKN1	S46	T52I	52	Missense	distal	6	no	60.429	60.106	EPSD	TCGA;ICGC;COSMIC	59.390	Down-regulation
AGC_PKN_PKN1_ST	P10636	MAPT	Q16512	PKN1	S46	P47S	47	Missense	proximal	1	no	60.429	54.124	EPSD	TCGA;ICGC;COSMIC	59.390	Loss
AGC_PKN_PKN1_ST	P10636	MAPT	Q16512	PKN1	S46	P47L	47	Missense	proximal	1	no	60.429	60.826	EPSD	TCGA;ICGC;COSMIC	59.390	Up-regulation
AGC_PKN_PKN1_ST	P10636	MAPT	Q16512	PKN1	S46	G42C	42	Missense	distal	-4	no	60.429	55.632	EPSD	TCGA;ICGC;COSMIC	59.390	Loss
AGC_PKN_PKN1_ST	P10636	MAPT	Q16512	PKN1	S64	A66S	66	Missense	proximal	2	no	61.972	61.968	EPSD	TCGA;ICGC;COSMIC	59.390	Down-regulation
AGC_PKN_PKN1_ST	P10636	MAPT	Q16512	PKN1	S64	P59L	59	Missense	distal	-5	no	61.972	63.083	EPSD	TCGA;ICGC;COSMIC	59.390	Up-regulation
AGC_PKN_PKN1_ST	P10636	MAPT	Q16512	PKN1	S64	P59T	59	Missense	distal	-5	no	61.972	62.027	EPSD	TCGA;ICGC;COSMIC	59.390	Up-regulation
AGC_PKN_PKN1_ST	P10636	MAPT	Q16512	PKN1	S64	G60S	60	Missense	distal	-4	no	61.972	63.325	EPSD	TCGA;ICGC;COSMIC	59.390	Up-regulation
AGC_PKN_PKN1_ST	P10636	MAPT	Q16512	PKN1	T167	R168H	168	Missense	proximal	1	no	80.887	72.304	EPSD	TCGA;ICGC;COSMIC	59.390	Down-regulation
AGC_PKN_PKN1_ST	P10636	MAPT	Q16512	PKN1	T167	R168C	168	Missense	proximal	1	no	80.887	79.171	EPSD	TCGA;ICGC;COSMIC	59.390	Down-regulation
AGC_PKN_PKN1_ST	P10636	MAPT	Q16512	PKN1	S171	R168H	168	Missense	distal	-3	no	79.050	57.988	EPSD	TCGA;ICGC;COSMIC	59.390	Loss
AGC_PKN_PKN1_ST	P10636	MAPT	Q16512	PKN1	S171	R168C	168	Missense	distal	-3	no	79.050	2.187	EPSD	TCGA;ICGC;COSMIC	59.390	Loss
AGC_PKN_PKN1_ST	P10636	MAPT	Q16512	PKN1	S214	P212L	212	Missense	proximal	-2	no	64.058	65.745	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	59.390	Up-regulation
AGC_PKN_PKN1_ST	P10636	MAPT	Q16512	PKN1	S214	E220K	220	Missense	distal	6	no	64.058	64.764	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	59.390	Up-regulation
AGC_PKN_PKN1_ST	P10636	MAPT	Q16512	PKN1	S341	G339R	339	Missense	proximal	-2	no	51.259	60.024	EPSD	TCGA;ICGC;COSMIC	59.390	Gain
AGC_PKN_PKN1_ST	P10636	MAPT	Q16512	PKN1	S369	Q373R	373	Missense	distal	4	no	64.889	66.210	EPSD	TCGA;ICGC;COSMIC	59.390	Up-regulation
AGC_PKN_PKN1_ST	P10636	MAPT	Q16512	PKN1	S369	K366E	366	Missense	distal	-3	no	64.889	11.973	EPSD	TCGA;ICGC;COSMIC	59.390	Loss
AGC_PKN_PKN1_ST	P10636	MAPT	Q16512	PKN1	T386	G387R	387	Missense	proximal	1	no	72.789	71.858	EPSD	TCGA;COSMIC	59.390	Down-regulation
AGC_PKN_PKN1_ST	P10636	MAPT	Q16512	PKN1	T416	P415L	415	Missense	proximal	-1	no	83.277	81.645	EPSD	TCGA;ICGC;COSMIC	59.390	Down-regulation
AGC_PKN_PKN1_ST	P10636	MAPT	Q16512	PKN1	S451	E456K	456	Missense	distal	5	no	63.672	64.199	EPSD	TCGA;ICGC;COSMIC	59.390	Up-regulation
AGC_PKN_PKN1_ST	P10636	MAPT	Q16512	PKN1	S451	S452C	452	Missense	proximal	1	no	63.672	71.968	EPSD	TCGA;ICGC;COSMIC	59.390	Up-regulation
AGC_PKN_PKN1_ST	P10636	MAPT	Q16512	PKN1	S451	S444F	444	Missense	distal	-7	no	63.672	63.570	EPSD	TCGA;ICGC	59.390	Down-regulation
AGC_PKN_PKN1_ST	P10636	MAPT	Q16512	PKN1	S451	S452Y	452	Missense	proximal	1	no	63.672	68.961	EPSD	TCGA;ICGC;COSMIC	59.390	Up-regulation
AGC_PKN_PKN1_ST	P10636	MAPT	Q16512	PKN1	T470	R472Q	472	Missense	proximal	2	no	67.800	66.311	EPSD	TCGA	59.390	Down-regulation
AGC_PKN_PKN1_ST	P10636	MAPT	Q16512	PKN1	T470	R472W	472	Missense	proximal	2	no	67.800	65.662	EPSD	TCGA;COSMIC	59.390	Down-regulation
AGC_PKN_PKN1_ST	P10636	MAPT	Q16512	PKN1	T486	A485T	485	Missense	proximal	-1	no	59.274	61.906	EPSD	TCGA;COSMIC;GDSC;CCLE	59.390	Gain
AGC_PKN_PKN1_ST	P10636	MAPT	Q16512	PKN1	T498	P493Q	493	Missense	distal	-5	no	59.929	59.723	EPSD	TCGA;COSMIC	59.390	Down-regulation
AGC_PKN_PKN1_ST	P00533	EGFR	Q16512	PKN1	S246	R252C	252	Missense	distal	6	no	63.581	62.226	EPSD	TCGA;COSMIC	59.390	Down-regulation
AGC_PKN_PKN1_ST	P00533	EGFR	Q16512	PKN1	S246	R252P	252	Missense	distal	6	no	63.581	62.927	EPSD	TCGA;COSMIC	59.390	Down-regulation
AGC_PKN_PKN1_ST	P00533	EGFR	Q16512	PKN1	S246	C240Y	240	Missense	distal	-6	no	63.581	63.847	EPSD	TCGA;COSMIC	59.390	Up-regulation
AGC_PKN_PKN1_ST	P00533	EGFR	Q16512	PKN1	S246	R252H	252	Missense	distal	6	no	63.581	62.688	EPSD	TCGA;COSMIC	59.390	Down-regulation
AGC_PKN_PKN1_ST	P00533	EGFR	Q16512	PKN1	S246	D247N	247	Missense	proximal	1	no	63.581	62.273	EPSD	TCGA;COSMIC	59.390	Down-regulation
AGC_PKN_PKN1_ST	P00533	EGFR	Q16512	PKN1	S246	G239S	239	Missense	distal	-7	no	63.581	63.656	EPSD	TCGA;COSMIC	59.390	Up-regulation
AGC_PKN_PKN1_ST	P00533	EGFR	Q16512	PKN1	T678	R675W	675	Missense	distal	-3	no	83.114	41.682	PhosphoSitePlus	TCGA	59.390	Loss
AGC_PKN_PKN1_ST	P00533	EGFR	Q16512	PKN1	T678	R677H	677	Missense	proximal	-1	no	83.114	85.757	PhosphoSitePlus	TCGA;COSMIC	59.390	Up-regulation
AGC_PKN_PKN1_ST	P00533	EGFR	Q16512	PKN1	T678	R681M	681	Missense	distal	3	no	83.114	81.209	PhosphoSitePlus	TCGA	59.390	Down-regulation
AGC_PKN_PKN1_ST	P00533	EGFR	Q16512	PKN1	T678	Q684H	684	Missense	distal	6	no	83.114	83.176	PhosphoSitePlus	TCGA	59.390	Up-regulation
AGC_PKN_PKN1_ST	P00533	EGFR	Q16512	PKN1	T678	T678M	678	Missense	central	0	yes	83.114	0.000	PhosphoSitePlus	TCGA;GDSC;CCLE	59.390	Loss
AGC_PKN_PKN1_ST	P00533	EGFR	Q16512	PKN1	T892	H893Y	893	Missense	proximal	1	no	57.284	61.144	EPSD	TCGA;COSMIC	59.390	Gain
AGC_PKN_PKN1_ST	P00533	EGFR	Q16512	PKN1	T1032	R1031Q	1031	Missense	proximal	-1	no	60.397	65.668	EPSD	TCGA;COSMIC	59.390	Up-regulation
AGC_PKN_PKN1_ST	P00533	EGFR	Q16512	PKN1	S1070	R1068Q	1068	Missense	proximal	-2	no	61.483	56.127	EPSD	TCGA;COSMIC	59.390	Loss
AGC_PKN_PKN1_ST	P00533	EGFR	Q16512	PKN1	T1145	L1139F	1139	Missense	distal	-6	no	58.821	59.898	EPSD	TCGA;COSMIC	59.390	Gain
AGC_PKN_PKN1_ST	P00533	EGFR	Q16512	PKN1	T1145	V1147A	1147	Missense	proximal	2	no	58.821	60.250	EPSD	TCGA;ICGC	59.390	Gain
AGC_PKN_PKN1_ST	P00533	EGFR	Q16512	PKN1	S1162	S1162C	1162	Missense	central	0	yes	60.254	0.000	EPSD	TCGA;ICGC;COSMIC	59.390	Loss
AGC_PKN_PKN1_ST	P00533	EGFR	Q16512	PKN1	S1162	L1167M	1167	Missense	distal	5	no	60.254	60.020	EPSD	TCGA;ICGC;COSMIC	59.390	Down-regulation
AGC_PKN_PKN1_ST	Q9UQL6	HDAC5	Q16512	PKN1	T70	Q75K	75	Missense	distal	5	no	59.610	59.826	EPSD	TCGA;ICGC;COSMIC	59.390	Up-regulation
AGC_PKN_PKN1_ST	O15553	MEFV	Q16512	PKN1	S141	G138A	138	Missense	distal	-3	no	25.710	62.542	EPSD	TCGA;ICGC;COSMIC	59.390	Gain
AGC_PKN_PKN1_ST	O15553	MEFV	Q16512	PKN1	S179	G185E	185	Missense	distal	6	no	69.033	68.313	EPSD	TCGA;ICGC;COSMIC	59.390	Down-regulation
AGC_PKN_PKN1_ST	O15553	MEFV	Q16512	PKN1	S179	G185R	185	Missense	distal	6	no	69.033	69.754	EPSD	TCGA;ICGC;COSMIC	59.390	Up-regulation
AGC_PKN_PKN1_ST	O15553	MEFV	Q16512	PKN1	S208	A210V	210	Missense	proximal	2	no	89.788	88.359	PhosphoSitePlus;EPSD	TCGA;ICGC;COSMIC	59.390	Down-regulation
AGC_PKN_PKN1_ST	O15553	MEFV	Q16512	PKN1	S208	R204H	204	Missense	distal	-4	no	89.788	88.369	PhosphoSitePlus;EPSD	TCGA;ICGC;COSMIC	59.390	Down-regulation
AGC_PKN_PKN1_ST	O15553	MEFV	Q16512	PKN1	S208	R204S	204	Missense	distal	-4	no	89.788	89.905	PhosphoSitePlus;EPSD	TCGA;ICGC;COSMIC	59.390	Up-regulation
AGC_PKN_PKN1_ST	O15553	MEFV	Q16512	PKN1	S208	G215E	215	Missense	distal	7	no	89.788	89.679	PhosphoSitePlus;EPSD	TCGA;ICGC;COSMIC	59.390	Down-regulation
AGC_PKN_PKN1_ST	O15553	MEFV	Q16512	PKN1	S208	G211R	211	Missense	distal	3	no	89.788	89.366	PhosphoSitePlus;EPSD	TCGA;ICGC;COSMIC;GDSC;CCLE	59.390	Down-regulation
AGC_PKN_PKN1_ST	O15553	MEFV	Q16512	PKN1	S208	R205K	205	Missense	distal	-3	no	89.788	71.652	PhosphoSitePlus;EPSD	TCGA;ICGC;COSMIC	59.390	Down-regulation
AGC_PKN_PKN1_ST	O15553	MEFV	Q16512	PKN1	S242	G236R	236	Missense	distal	-6	no	83.262	82.849	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	59.390	Down-regulation
AGC_PKN_PKN1_ST	O15553	MEFV	Q16512	PKN1	S242	T246N	246	Missense	distal	4	no	83.262	87.313	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	59.390	Up-regulation
AGC_PKN_PKN1_ST	O15553	MEFV	Q16512	PKN1	S242	T246I	246	Missense	distal	4	no	83.262	75.693	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	59.390	Down-regulation
AGC_PKN_PKN1_ST	O15553	MEFV	Q16512	PKN1	S242	R239Q	239	Missense	distal	-3	no	83.262	73.580	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	59.390	Down-regulation
AGC_PKN_PKN1_ST	O15553	MEFV	Q16512	PKN1	S242	G236V	236	Missense	distal	-6	no	83.262	82.867	EPSD;PhosphoSitePlus	TCGA;ICGC	59.390	Down-regulation
AGC_PKN_PKN1_ST	P30622	CLIP1	Q16512	PKN1	T27	V33L	33	Missense	distal	6	no	60.772	60.786	EPSD	TCGA;ICGC;COSMIC	59.390	Up-regulation
AGC_PKN_PKN1_ST	P30622	CLIP1	Q16512	PKN1	S180	P184A	184	Missense	distal	4	no	58.830	61.769	EPSD	TCGA;ICGC;COSMIC;GDSC;CCLE	59.390	Gain
AGC_PKN_PKN1_ST	P30622	CLIP1	Q16512	PKN1	S180	P184L	184	Missense	distal	4	no	58.830	60.574	EPSD	TCGA;ICGC;COSMIC	59.390	Gain
AGC_PKN_PKN1_ST	P30622	CLIP1	Q16512	PKN1	S180	E178K	178	Missense	proximal	-2	no	58.830	67.769	EPSD	TCGA;ICGC;COSMIC	59.390	Gain
AGC_PKN_PKN1_ST	P30622	CLIP1	Q16512	PKN1	S180	P184S	184	Missense	distal	4	no	58.830	62.273	EPSD	TCGA;ICGC;COSMIC	59.390	Gain
AGC_PKN_PKN1_ST	P30622	CLIP1	Q16512	PKN1	S186	P184A	184	Missense	proximal	-2	no	60.580	67.092	EPSD	TCGA;ICGC;COSMIC;GDSC;CCLE	59.390	Up-regulation
AGC_PKN_PKN1_ST	P30622	CLIP1	Q16512	PKN1	S186	K190T	190	Missense	distal	4	no	60.580	63.924	EPSD	TCGA;ICGC;COSMIC	59.390	Up-regulation
AGC_PKN_PKN1_ST	P30622	CLIP1	Q16512	PKN1	S186	P184L	184	Missense	proximal	-2	no	60.580	62.267	EPSD	TCGA;ICGC;COSMIC	59.390	Up-regulation
AGC_PKN_PKN1_ST	P30622	CLIP1	Q16512	PKN1	S186	P184S	184	Missense	proximal	-2	no	60.580	67.823	EPSD	TCGA;ICGC;COSMIC	59.390	Up-regulation
AGC_PKN_PKN1_ST	P30622	CLIP1	Q16512	PKN1	S193	K190T	190	Missense	distal	-3	no	59.377	68.640	EPSD	TCGA;ICGC;COSMIC	59.390	Gain
AGC_PKN_PKN1_ST	P30622	CLIP1	Q16512	PKN1	S306	A305T	305	Missense	proximal	-1	no	63.911	66.543	EPSD	TCGA;COSMIC	59.390	Up-regulation
AGC_PKN_PKN1_ST	P30622	CLIP1	Q16512	PKN1	S306	A305G	305	Missense	proximal	-1	no	63.911	64.370	EPSD	TCGA;ICGC;COSMIC	59.390	Up-regulation
AGC_PKN_PKN1_ST	P30622	CLIP1	Q16512	PKN1	S312	A305T	305	Missense	distal	-7	no	88.259	88.292	PhosphoSitePlus	TCGA;COSMIC	59.390	Up-regulation
AGC_PKN_PKN1_ST	P30622	CLIP1	Q16512	PKN1	S312	A305G	305	Missense	distal	-7	no	88.259	88.186	PhosphoSitePlus	TCGA;ICGC;COSMIC	59.390	Down-regulation
AGC_PKN_PKN1_ST	P30622	CLIP1	Q16512	PKN1	S320	S321L	321	Missense	proximal	1	no	68.123	74.825	EPSD	TCGA;ICGC;COSMIC	59.390	Up-regulation
AGC_PKN_PKN1_ST	P30622	CLIP1	Q16512	PKN1	S320	A323V	323	Missense	distal	3	no	68.123	67.764	EPSD	TCGA;COSMIC	59.390	Down-regulation
AGC_PKN_PKN1_ST	P30622	CLIP1	Q16512	PKN1	S328	S321L	321	Missense	distal	-7	no	62.490	62.489	EPSD	TCGA;ICGC;COSMIC	59.390	Down-regulation
AGC_PKN_PKN1_ST	P30622	CLIP1	Q16512	PKN1	S328	A323V	323	Missense	distal	-5	no	62.490	62.374	EPSD	TCGA;COSMIC	59.390	Down-regulation
AGC_PKN_PKN1_ST	P30622	CLIP1	Q16512	PKN1	S784	R780W	780	Missense	distal	-4	no	63.519	59.667	EPSD	TCGA;COSMIC	59.390	Down-regulation
AGC_PKN_PKN1_ST	P30622	CLIP1	Q16512	PKN1	S784	R780Q	780	Missense	distal	-4	no	63.519	63.641	EPSD	TCGA;COSMIC	59.390	Up-regulation
AGC_PKN_PKN1_ST	P30622	CLIP1	Q16512	PKN1	T822	L825F	825	Missense	distal	3	no	59.192	59.474	EPSD	TCGA;COSMIC	59.390	Gain
AGC_PKN_PKN1_ST	P30622	CLIP1	Q16512	PKN1	T1087	A1088V	1088	Missense	proximal	1	no	55.751	60.864	EPSD	TCGA	59.390	Gain
AGC_PKN_PKN1_ST	P30622	CLIP1	Q16512	PKN1	S1304	Q1311E	1311	Missense	distal	7	no	63.033	63.316	EPSD	TCGA;COSMIC	59.390	Up-regulation
Atypical_PIKK_SMG1_SMG1_ST	Q92900	UPF1	Q96Q15	SMG1	S10	E4Q	4	Missense	distal	-6	no	2.923	2.899	EPSD	TCGA	1.372	Down-regulation
Atypical_PIKK_SMG1_SMG1_ST	Q92900	UPF1	Q96Q15	SMG1	S10	E4K	4	Missense	distal	-6	no	2.923	2.919	EPSD	TCGA;ICGC;COSMIC	1.372	Down-regulation
Atypical_PIKK_SMG1_SMG1_ST	Q92900	UPF1	Q96Q15	SMG1	T28	E32Q	32	Missense	distal	4	no	5.668	5.597	PhosphoSitePlus;EPSD	TCGA;ICGC;COSMIC	1.372	Down-regulation
Atypical_PIKK_SMG1_SMG1_ST	Q92900	UPF1	Q96Q15	SMG1	T28	S31C	31	Missense	distal	3	no	5.668	5.374	PhosphoSitePlus;EPSD	TCGA;ICGC;COSMIC	1.372	Down-regulation
Atypical_PIKK_SMG1_SMG1_ST	Q92900	UPF1	Q96Q15	SMG1	T28	E34K	34	Missense	distal	6	no	5.668	5.674	PhosphoSitePlus;EPSD	TCGA;ICGC;COSMIC	1.372	Up-regulation
Atypical_PIKK_SMG1_SMG1_ST	Q92900	UPF1	Q96Q15	SMG1	T28	F33L	33	Missense	distal	5	no	5.668	5.674	PhosphoSitePlus;EPSD	TCGA;ICGC;COSMIC	1.372	Up-regulation
Atypical_PIKK_SMG1_SMG1_ST	Q92900	UPF1	Q96Q15	SMG1	S31	E32Q	32	Missense	proximal	1	no	0.402	3.134	EPSD	TCGA;ICGC;COSMIC	1.372	Gain
Atypical_PIKK_SMG1_SMG1_ST	Q92900	UPF1	Q96Q15	SMG1	S215	S217N	217	Missense	proximal	2	no	3.393	3.389	EPSD	TCGA;ICGC;COSMIC	1.372	Down-regulation
Atypical_PIKK_SMG1_SMG1_ST	Q92900	UPF1	Q96Q15	SMG1	S215	I222F	222	Missense	distal	7	no	3.393	3.463	EPSD	TCGA;ICGC;COSMIC	1.372	Up-regulation
Atypical_PIKK_SMG1_SMG1_ST	Q92900	UPF1	Q96Q15	SMG1	S247	P246L	246	Missense	proximal	-1	no	0.653	1.857	EPSD	TCGA;ICGC;COSMIC	1.372	Gain
Atypical_PIKK_SMG1_SMG1_ST	P04637	TP53	Q96Q15	SMG1	S33	P27S	27	Missense	distal	-6	no	1.652	1.645	EPSD	TCGA;ICGC;COSMIC	1.372	Down-regulation
Atypical_PIKK_SMG1_SMG1_ST	P04637	TP53	Q96Q15	SMG1	S33	P27L	27	Missense	distal	-6	no	1.652	1.642	EPSD	TCGA;ICGC;COSMIC;GDSC;CCLE	1.372	Down-regulation
Atypical_PIKK_SMG1_SMG1_ST	P04637	TP53	Q96Q15	SMG1	S99	G105C	105	Missense	distal	6	no	3.102	3.114	EPSD	TCGA;ICGC;COSMIC;GDSC	1.372	Up-regulation
Atypical_PIKK_SMG1_SMG1_ST	P04637	TP53	Q96Q15	SMG1	S99	S106R	106	Missense	distal	7	no	3.102	3.084	EPSD	TCGA;ICGC;COSMIC;GDSC;CCLE	1.372	Down-regulation
Atypical_PIKK_SMG1_SMG1_ST	P04637	TP53	Q96Q15	SMG1	S99	G105R	105	Missense	distal	6	no	3.102	3.113	EPSD	TCGA;ICGC;COSMIC;CCLE	1.372	Up-regulation
Atypical_PIKK_SMG1_SMG1_ST	P04637	TP53	Q96Q15	SMG1	S99	G105V	105	Missense	distal	6	no	3.102	3.106	EPSD	TCGA;ICGC;COSMIC	1.372	Up-regulation
Atypical_PIKK_SMG1_SMG1_ST	P04637	TP53	Q96Q15	SMG1	S99	G105S	105	Missense	distal	6	no	3.102	3.123	EPSD	TCGA;ICGC;COSMIC	1.372	Up-regulation
Atypical_PIKK_SMG1_SMG1_ST	P04637	TP53	Q96Q15	SMG1	S99	V97D	97	Missense	proximal	-2	no	3.102	3.101	EPSD	TCGA;ICGC;COSMIC	1.372	Down-regulation
Atypical_PIKK_SMG1_SMG1_ST	P04637	TP53	Q96Q15	SMG1	S99	P92S	92	Missense	distal	-7	no	3.102	3.119	EPSD	TCGA;ICGC	1.372	Up-regulation
Atypical_PIKK_SMG1_SMG1_ST	P04637	TP53	Q96Q15	SMG1	S215	H214L	214	Missense	proximal	-1	no	0.632	1.722	EPSD	TCGA;ICGC;COSMIC	1.372	Gain
Atypical_PIKK_SMG1_SMG1_ST	P04637	TP53	Q96Q15	SMG1	T284	E285Q	285	Missense	proximal	1	no	0.265	2.997	EPSD	TCGA;ICGC;COSMIC	1.372	Gain
STE_STE11_ASK_MAP3K6_ST	P45983	MAPK8	O95382	MAP3K6	T178	T178M	178	Missense	central	0	yes	1.978	0.000	EPSD	TCGA;ICGC;COSMIC	1.891	Loss
STE_STE11_ASK_MAP3K6_ST	P45983	MAPK8	O95382	MAP3K6	T178	P184L	184	Missense	distal	6	no	1.978	2.132	EPSD	TCGA;ICGC;COSMIC	1.891	Up-regulation
STE_STE11_ASK_MAP3K6_ST	P45983	MAPK8	O95382	MAP3K6	T183	T178M	178	Missense	distal	-5	no	15.332	12.958	PhosphoSitePlus;EPSD	TCGA;ICGC;COSMIC	1.891	Down-regulation
STE_STE11_ASK_MAP3K6_ST	P45983	MAPK8	O95382	MAP3K6	T183	P184L	184	Missense	proximal	1	no	15.332	15.235	PhosphoSitePlus;EPSD	TCGA;ICGC;COSMIC	1.891	Down-regulation
STE_STE11_ASK_MAP3K6_ST	P45983	MAPK8	O95382	MAP3K6	T183	R189C	189	Missense	distal	6	no	15.332	14.613	PhosphoSitePlus;EPSD	TCGA;ICGC;COSMIC	1.891	Down-regulation
STE_STE11_ASK_MAP3K6_ST	P45983	MAPK8	O95382	MAP3K6	T183	R189L	189	Missense	distal	6	no	15.332	14.661	PhosphoSitePlus;EPSD	TCGA;ICGC;COSMIC	1.891	Down-regulation
STE_STE11_ASK_MAP3K6_ST	P45983	MAPK8	O95382	MAP3K6	T183	R189H	189	Missense	distal	6	no	15.332	14.639	PhosphoSitePlus;EPSD	TCGA;ICGC;COSMIC	1.891	Down-regulation
STE_STE11_ASK_MAP3K6_ST	P45983	MAPK8	O95382	MAP3K6	T188	P184L	184	Missense	distal	-4	no	1.928	1.817	EPSD	TCGA;ICGC;COSMIC	1.891	Loss
STE_STE11_ASK_MAP3K6_ST	P45983	MAPK8	O95382	MAP3K6	T188	R189C	189	Missense	proximal	1	no	1.928	1.835	EPSD	TCGA;ICGC;COSMIC	1.891	Loss
STE_STE11_ASK_MAP3K6_ST	P45983	MAPK8	O95382	MAP3K6	T188	R189L	189	Missense	proximal	1	no	1.928	1.891	EPSD	TCGA;ICGC;COSMIC	1.891	Down-regulation
STE_STE11_ASK_MAP3K6_ST	P45983	MAPK8	O95382	MAP3K6	T188	E195K	195	Missense	distal	7	no	1.928	2.624	EPSD	TCGA;ICGC;COSMIC	1.891	Up-regulation
STE_STE11_ASK_MAP3K6_ST	P45983	MAPK8	O95382	MAP3K6	T188	R189H	189	Missense	proximal	1	no	1.928	1.885	EPSD	TCGA;ICGC;COSMIC	1.891	Loss
STE_STE11_ASK_MAP3K6_ST	P45983	MAPK8	O95382	MAP3K6	T367	V360G	360	Missense	distal	-7	no	2.498	2.582	EPSD	TCGA;COSMIC	1.891	Up-regulation
STE_STE11_ASK_MAP3K6_ST	O95382	MAP3K6	O95382	MAP3K6	T793	A798T	798	Missense	distal	5	no	2.019	2.499	EPSD	TCGA;ICGC	1.891	Up-regulation
STE_STE11_ASK_MAP3K6_ST	O95382	MAP3K6	O95382	MAP3K6	T793	G792D	792	Missense	proximal	-1	no	2.019	2.010	EPSD	TCGA;ICGC;COSMIC	1.891	Down-regulation
STE_STE11_ASK_MAP3K6_ST	O95382	MAP3K6	O95382	MAP3K6	S917	S912N	912	Missense	distal	-5	no	0.052	2.065	EPSD	TCGA	1.891	Gain
STE_STE11_ASK_MAP3K6_ST	O95382	MAP3K6	O95382	MAP3K6	S938	Q943E	943	Missense	distal	5	no	2.245	2.084	EPSD	TCGA;ICGC;COSMIC	1.891	Down-regulation
STE_STE11_ASK_MAP3K6_ST	O95382	MAP3K6	O95382	MAP3K6	T944	Q943E	943	Missense	proximal	-1	no	3.665	3.849	EPSD	TCGA;ICGC;COSMIC	1.891	Up-regulation
STE_STE11_ASK_MAP3K6_ST	Q16539	MAPK14	O95382	MAP3K6	T175	R173W	173	Missense	proximal	-2	no	2.601	2.580	EPSD	TCGA;ICGC;CCLE	1.891	Down-regulation
STE_STE11_ASK_MAP3K6_ST	Q16539	MAPK14	O95382	MAP3K6	T180	R186K	186	Missense	distal	6	no	15.416	14.793	PhosphoSitePlus;EPSD	TCGA;ICGC;COSMIC	1.891	Down-regulation
STE_STE11_ASK_MAP3K6_ST	Q16539	MAPK14	O95382	MAP3K6	T180	R173W	173	Missense	distal	-7	no	15.416	15.384	PhosphoSitePlus;EPSD	TCGA;ICGC;CCLE	1.891	Down-regulation
STE_STE11_ASK_MAP3K6_ST	Q16539	MAPK14	O95382	MAP3K6	T185	P191S	191	Missense	distal	6	no	2.339	2.338	EPSD	TCGA;ICGC;COSMIC	1.891	Down-regulation
STE_STE11_ASK_MAP3K6_ST	Q16539	MAPK14	O95382	MAP3K6	T185	E192Q	192	Missense	distal	7	no	2.339	2.488	EPSD	TCGA;ICGC;COSMIC	1.891	Up-regulation
STE_STE11_ASK_MAP3K6_ST	Q16539	MAPK14	O95382	MAP3K6	T185	P191H	191	Missense	distal	6	no	2.339	2.471	EPSD	TCGA;ICGC;COSMIC	1.891	Up-regulation
STE_STE11_ASK_MAP3K6_ST	Q16539	MAPK14	O95382	MAP3K6	T185	R186K	186	Missense	proximal	1	no	2.339	2.309	EPSD	TCGA;ICGC;COSMIC	1.891	Down-regulation
CAMK_DAPK_DAPK_DAPK1_ST	P53355	DAPK1	P53355	DAPK1	S57	R58H	58	Missense	proximal	1	no	10.150	9.600	EPSD	TCGA;ICGC;COSMIC	8.849	Down-regulation
CAMK_DAPK_DAPK_DAPK1_ST	P53355	DAPK1	P53355	DAPK1	S57	R54W	54	Missense	distal	-3	no	10.150	7.442	EPSD	TCGA;ICGC	8.849	Loss
CAMK_DAPK_DAPK_DAPK1_ST	P53355	DAPK1	P53355	DAPK1	S57	R54Q	54	Missense	distal	-3	no	10.150	5.937	EPSD	TCGA;ICGC;COSMIC	8.849	Loss
CAMK_DAPK_DAPK_DAPK1_ST	P53355	DAPK1	P53355	DAPK1	S57	S51F	51	Missense	distal	-6	no	10.150	8.056	EPSD	TCGA	8.849	Loss
CAMK_DAPK_DAPK_DAPK1_ST	P53355	DAPK1	P53355	DAPK1	S57	R53Q	53	Missense	distal	-4	no	10.150	9.953	EPSD	TCGA;ICGC	8.849	Down-regulation
CAMK_DAPK_DAPK_DAPK1_ST	P53355	DAPK1	P53355	DAPK1	S57	R58C	58	Missense	proximal	1	no	10.150	10.359	EPSD	TCGA;COSMIC	8.849	Up-regulation
CAMK_DAPK_DAPK_DAPK1_ST	P53355	DAPK1	P53355	DAPK1	S308	R310C	310	Missense	proximal	2	no	14.981	15.446	PhosphoSitePlus	TCGA;ICGC;COSMIC	8.849	Up-regulation
CAMK_DAPK_DAPK_DAPK1_ST	P53355	DAPK1	P53355	DAPK1	S313	R310C	310	Missense	distal	-3	no	15.405	10.577	EPSD	TCGA;ICGC;COSMIC	8.849	Down-regulation
CAMK_DAPK_DAPK_DAPK1_ST	P53355	DAPK1	P53355	DAPK1	S313	R317I	317	Missense	distal	4	no	15.405	15.955	EPSD	TCGA;ICGC;COSMIC	8.849	Up-regulation
CAMK_DAPK_DAPK_DAPK1_ST	P53355	DAPK1	P53355	DAPK1	S319	R317I	317	Missense	proximal	-2	no	11.303	9.175	EPSD	TCGA;ICGC;COSMIC	8.849	Down-regulation
CAMK_DAPK_DAPK_DAPK1_ST	P53355	DAPK1	P53355	DAPK1	S324	R317I	317	Missense	distal	-7	no	6.288	9.609	EPSD	TCGA;ICGC;COSMIC	8.849	Gain
CAMK_DAPK_DAPK_DAPK1_ST	P53355	DAPK1	P53355	DAPK1	S326	M328V	328	Missense	proximal	2	no	8.740	9.103	EPSD	TCGA;ICGC;COSMIC	8.849	Gain
CAMK_DAPK_DAPK_DAPK1_ST	P53355	DAPK1	P53355	DAPK1	S635	A638V	638	Missense	distal	3	no	11.113	10.949	EPSD	TCGA;ICGC;COSMIC	8.849	Down-regulation
CAMK_DAPK_DAPK_DAPK1_ST	P53355	DAPK1	P53355	DAPK1	S635	D642N	642	Missense	distal	7	no	11.113	11.312	EPSD	TCGA;ICGC;COSMIC	8.849	Up-regulation
CAMK_DAPK_DAPK_DAPK1_ST	P53355	DAPK1	P53355	DAPK1	S728	P733H	733	Missense	distal	5	no	9.630	9.011	EPSD	TCGA	8.849	Down-regulation
CAMK_DAPK_DAPK_DAPK1_ST	P53355	DAPK1	P53355	DAPK1	S728	P735L	735	Missense	distal	7	no	9.630	10.860	EPSD	TCGA;ICGC;COSMIC	8.849	Up-regulation
CAMK_DAPK_DAPK_DAPK1_ST	P53355	DAPK1	P53355	DAPK1	S728	P721S	721	Missense	distal	-7	no	9.630	8.518	EPSD	TCGA;ICGC;COSMIC	8.849	Loss
CAMK_DAPK_DAPK_DAPK1_ST	P53355	DAPK1	P53355	DAPK1	S762	M763T	763	Missense	proximal	1	no	9.106	9.254	EPSD	TCGA;ICGC;COSMIC	8.849	Up-regulation
CAMK_DAPK_DAPK_DAPK1_ST	P53355	DAPK1	P53355	DAPK1	S762	V756M	756	Missense	distal	-6	no	9.106	10.367	EPSD	TCGA;ICGC	8.849	Up-regulation
CAMK_DAPK_DAPK_DAPK1_ST	P53355	DAPK1	P53355	DAPK1	S762	F765L	765	Missense	distal	3	no	9.106	8.588	EPSD	TCGA;ICGC;COSMIC	8.849	Loss
CAMK_DAPK_DAPK_DAPK1_ST	P53355	DAPK1	P53355	DAPK1	T1053	V1051M	1051	Missense	proximal	-2	no	5.792	10.073	EPSD	TCGA;ICGC;COSMIC;GDSC	8.849	Gain
CAMK_DAPK_DAPK_DAPK1_ST	O95786	DDX58	P53355	DAPK1	S654	G659D	659	Missense	distal	5	no	16.697	17.197	PhosphoSitePlus;EPSD	TCGA;COSMIC	8.849	Up-regulation
CAMK_DAPK_DAPK_DAPK1_ST	O95786	DDX58	P53355	DAPK1	T667	G665S	665	Missense	proximal	-2	no	16.192	17.717	EPSD;PhosphoSitePlus	TCGA;COSMIC	8.849	Up-regulation
CAMK_DAPK_DAPK_DAPK1_ST	O95786	DDX58	P53355	DAPK1	T671	G665S	665	Missense	distal	-6	no	15.563	17.455	EPSD;PhosphoSitePlus	TCGA;COSMIC	8.849	Up-regulation
CAMK_DAPK_DAPK_DAPK1_ST	O95786	DDX58	P53355	DAPK1	S764	E758Q	758	Missense	distal	-6	no	15.563	15.318	EPSD;PhosphoSitePlus	TCGA;COSMIC	8.849	Down-regulation
CAMK_DAPK_DAPK_DAPK1_ST	O95786	DDX58	P53355	DAPK1	T770	A774S	774	Missense	distal	4	no	15.226	16.070	EPSD;PhosphoSitePlus	TCGA;COSMIC	8.849	Up-regulation
CAMK_DAPK_DAPK_DAPK1_ST	Q96RR4	CAMKK2	P53355	DAPK1	T145	R139G	139	Missense	distal	-6	no	9.938	7.896	EPSD	TCGA;ICGC;COSMIC	8.849	Loss
CAMK_DAPK_DAPK_DAPK1_ST	Q96RR4	CAMKK2	P53355	DAPK1	T145	R142W	142	Missense	distal	-3	no	9.938	7.229	EPSD	TCGA;ICGC;COSMIC	8.849	Loss
CAMK_DAPK_DAPK_DAPK1_ST	Q96RR4	CAMKK2	P53355	DAPK1	T350	T350M	350	Missense	central	0	yes	9.990	0.000	EPSD	TCGA;COSMIC	8.849	Loss
CAMK_DAPK_DAPK_DAPK1_ST	Q96RR4	CAMKK2	P53355	DAPK1	T350	L343H	343	Missense	distal	-7	no	9.990	10.420	EPSD	TCGA;ICGC;COSMIC	8.849	Up-regulation
CAMK_DAPK_DAPK_DAPK1_ST	Q96RR4	CAMKK2	P53355	DAPK1	T350	E357D	357	Missense	distal	7	no	9.990	9.714	EPSD	TCGA;ICGC;COSMIC	8.849	Down-regulation
CAMK_DAPK_DAPK_DAPK1_ST	Q96RR4	CAMKK2	P53355	DAPK1	S509	E507G	507	Missense	proximal	-2	no	9.171	9.337	EPSD	TCGA;ICGC;COSMIC	8.849	Up-regulation
CAMK_DAPK_DAPK_DAPK1_ST	Q96RR4	CAMKK2	P53355	DAPK1	S509	S509L	509	Missense	central	0	yes	9.171	0.000	EPSD	TCGA;ICGC;COSMIC	8.849	Loss
CAMK_DAPK_DAPK_DAPK1_ST	Q96RR4	CAMKK2	P53355	DAPK1	S511	E507G	507	Missense	distal	-4	no	15.718	15.692	PhosphoSitePlus	TCGA;ICGC;COSMIC	8.849	Down-regulation
CAMK_DAPK_DAPK_DAPK1_ST	Q96RR4	CAMKK2	P53355	DAPK1	S511	S509L	509	Missense	proximal	-2	no	15.718	15.578	PhosphoSitePlus	TCGA;ICGC;COSMIC	8.849	Down-regulation
CAMK_DAPK_DAPK_DAPK1_ST	Q96RR4	CAMKK2	P53355	DAPK1	T518	P521T	521	Missense	distal	3	no	9.782	10.961	EPSD	TCGA;ICGC;COSMIC	8.849	Up-regulation
CAMK_DAPK_DAPK_DAPK1_ST	Q96RR4	CAMKK2	P53355	DAPK1	T522	P521T	521	Missense	proximal	-1	no	9.295	9.746	EPSD	TCGA;ICGC;COSMIC	8.849	Up-regulation
CAMK_DAPK_DAPK_DAPK1_ST	Q00613	HSF1	P53355	DAPK1	S136	R133H	133	Missense	distal	-3	no	10.581	5.951	EPSD	TCGA;COSMIC	8.849	Loss
CAMK_DAPK_DAPK_DAPK1_ST	Q00613	HSF1	P53355	DAPK1	S136	I130V	130	Missense	distal	-6	no	10.581	11.813	EPSD	TCGA;COSMIC	8.849	Up-regulation
CAMK_DAPK_DAPK_DAPK1_ST	Q00613	HSF1	P53355	DAPK1	S216	S221Y	221	Missense	distal	5	no	9.469	9.757	EPSD	TCGA;COSMIC	8.849	Up-regulation
CAMK_DAPK_DAPK_DAPK1_ST	Q00613	HSF1	P53355	DAPK1	S218	S221Y	221	Missense	distal	3	no	10.859	11.679	EPSD	TCGA;COSMIC	8.849	Up-regulation
CAMK_DAPK_DAPK_DAPK1_ST	Q00613	HSF1	P53355	DAPK1	S279	P276L	276	Missense	distal	-3	no	10.183	10.048	EPSD	TCGA;COSMIC	8.849	Down-regulation
CAMK_DAPK_DAPK_DAPK1_ST	Q00613	HSF1	P53355	DAPK1	S279	E286K	286	Missense	distal	7	no	10.183	9.739	EPSD	TCGA;COSMIC	8.849	Down-regulation
CAMK_DAPK_DAPK_DAPK1_ST	Q00613	HSF1	P53355	DAPK1	S279	M277V	277	Missense	proximal	-2	no	10.183	5.902	EPSD	TCGA;COSMIC	8.849	Loss
CAMK_DAPK_DAPK_DAPK1_ST	Q00613	HSF1	P53355	DAPK1	S320	R317H	317	Missense	distal	-3	no	9.881	5.251	EPSD	TCGA;COSMIC	8.849	Loss
CAMK_DAPK_DAPK_DAPK1_ST	Q00613	HSF1	P53355	DAPK1	S320	T323I	323	Missense	distal	3	no	9.881	8.630	EPSD	TCGA;COSMIC	8.849	Loss
CAMK_DAPK_DAPK_DAPK1_ST	Q00613	HSF1	P53355	DAPK1	S320	S320F	320	Missense	central	0	yes	9.881	0.000	EPSD	TCGA;COSMIC	8.849	Loss
CAMK_DAPK_DAPK_DAPK1_ST	Q00613	HSF1	P53355	DAPK1	S320	P327L	327	Missense	distal	7	no	9.881	11.111	EPSD	TCGA	8.849	Up-regulation
CAMK_DAPK_DAPK_DAPK1_ST	Q00613	HSF1	P53355	DAPK1	S326	D332Y	332	Missense	distal	6	no	10.559	10.647	EPSD	TCGA;COSMIC	8.849	Up-regulation
CAMK_DAPK_DAPK_DAPK1_ST	Q00613	HSF1	P53355	DAPK1	S326	T323I	323	Missense	distal	-3	no	10.559	8.221	EPSD	TCGA;COSMIC	8.849	Loss
CAMK_DAPK_DAPK_DAPK1_ST	Q00613	HSF1	P53355	DAPK1	S326	S320F	320	Missense	distal	-6	no	10.559	8.465	EPSD	TCGA;COSMIC	8.849	Loss
CAMK_DAPK_DAPK_DAPK1_ST	Q00613	HSF1	P53355	DAPK1	S326	A329T	329	Missense	distal	3	no	10.559	11.083	EPSD	TCGA;COSMIC	8.849	Up-regulation
CAMK_DAPK_DAPK_DAPK1_ST	Q00613	HSF1	P53355	DAPK1	S326	S333F	333	Missense	distal	7	no	10.559	9.677	EPSD	TCGA;COSMIC	8.849	Down-regulation
CAMK_DAPK_DAPK_DAPK1_ST	Q00613	HSF1	P53355	DAPK1	S326	P327L	327	Missense	proximal	1	no	10.559	10.092	EPSD	TCGA	8.849	Down-regulation
CAMK_DAPK_DAPK_DAPK1_ST	Q00613	HSF1	P53355	DAPK1	S338	D332Y	332	Missense	distal	-6	no	9.574	8.773	EPSD	TCGA;COSMIC	8.849	Loss
CAMK_DAPK_DAPK_DAPK1_ST	Q00613	HSF1	P53355	DAPK1	S338	E339G	339	Missense	proximal	1	no	9.574	9.464	EPSD	TCGA;COSMIC	8.849	Down-regulation
CAMK_DAPK_DAPK_DAPK1_ST	Q00613	HSF1	P53355	DAPK1	S338	S333F	333	Missense	distal	-5	no	9.574	9.451	EPSD	TCGA;COSMIC	8.849	Down-regulation
CAMK_DAPK_DAPK_DAPK1_ST	Q00613	HSF1	P53355	DAPK1	S438	E441K	441	Missense	distal	3	no	10.117	10.246	EPSD	TCGA;COSMIC	8.849	Up-regulation
CAMK_DAPK_DAPK_DAPK1_ST	P40429	RPL13A	P53355	DAPK1	S67	N65K	65	Missense	proximal	-2	no	10.735	11.236	EPSD	TCGA;ICGC;COSMIC	8.849	Up-regulation
CAMK_DAPK_DAPK_DAPK1_ST	P40429	RPL13A	P53355	DAPK1	S67	R61W	61	Missense	distal	-6	no	10.735	9.843	EPSD	TCGA;ICGC;COSMIC	8.849	Down-regulation
CAMK_DAPK_DAPK_DAPK1_ST	P40429	RPL13A	P53355	DAPK1	S67	R68Q	68	Missense	proximal	1	no	10.735	10.147	EPSD	TCGA;ICGC;COSMIC	8.849	Down-regulation
CAMK_DAPK_DAPK_DAPK1_ST	P40429	RPL13A	P53355	DAPK1	S77	F80L	80	Missense	distal	3	no	16.021	15.503	PhosphoSitePlus	TCGA;ICGC	8.849	Down-regulation
CAMK_DAPK_DAPK_DAPK1_ST	P40429	RPL13A	P53355	DAPK1	T193	G200R	200	Missense	distal	7	no	8.354	8.991	EPSD	TCGA;ICGC	8.849	Gain
CAMK_DAPK_DAPK_DAPK1_ST	P40429	RPL13A	P53355	DAPK1	T193	K187E	187	Missense	distal	-6	no	8.354	9.382	EPSD	TCGA;ICGC;COSMIC	8.849	Gain
CAMK_DAPK_DAPK_DAPK1_ST	O14950	MYL12B	P53355	DAPK1	S20	R17C	17	Missense	distal	-3	no	13.300	8.473	PhosphoSitePlus	TCGA;ICGC;COSMIC	8.849	Loss
CAMK_DAPK_DAPK_DAPK1_ST	O14950	MYL12B	P53355	DAPK1	T135	D136Y	136	Missense	proximal	1	no	9.119	9.279	EPSD	TCGA;ICGC;COSMIC	8.849	Up-regulation
CAMK_DAPK_DAPK_DAPK1_ST	O14950	MYL12B	P53355	DAPK1	T135	F134L	134	Missense	proximal	-1	no	9.119	8.749	EPSD	TCGA;ICGC;COSMIC	8.849	Loss
CAMK_DAPK_DAPK_DAPK1_ST	Q14457	BECN1	P53355	DAPK1	T91	P84L	84	Missense	distal	-7	no	10.617	10.937	EPSD	TCGA;ICGC;COSMIC	8.849	Up-regulation
CAMK_DAPK_DAPK_DAPK1_ST	Q14457	BECN1	P53355	DAPK1	T91	T98P	98	Missense	distal	7	no	10.617	10.202	EPSD	TCGA;ICGC;COSMIC	8.849	Down-regulation
CAMK_DAPK_DAPK_DAPK1_ST	Q14457	BECN1	P53355	DAPK1	S96	T98P	98	Missense	proximal	2	no	9.141	9.754	EPSD	TCGA;ICGC;COSMIC	8.849	Up-regulation
CAMK_DAPK_DAPK_DAPK1_ST	Q14457	BECN1	P53355	DAPK1	T98	T98P	98	Missense	central	0	yes	9.650	0.000	EPSD	TCGA;ICGC;COSMIC	8.849	Loss
CAMK_DAPK_DAPK_DAPK1_ST	Q14457	BECN1	P53355	DAPK1	T119	R114Q	114	Missense	distal	-5	no	15.276	15.120	PhosphoSitePlus	TCGA;ICGC;COSMIC	8.849	Down-regulation
CAMK_DAPK_DAPK_DAPK1_ST	Q14457	BECN1	P53355	DAPK1	T119	L122F	122	Missense	distal	3	no	15.276	15.793	PhosphoSitePlus	TCGA;ICGC;COSMIC	8.849	Up-regulation
CAMK_DAPK_DAPK_DAPK1_ST	Q14457	BECN1	P53355	DAPK1	T119	G120W	120	Missense	proximal	1	no	15.276	15.034	PhosphoSitePlus	TCGA;ICGC;COSMIC	8.849	Down-regulation
CAMK_DAPK_DAPK_DAPK1_ST	Q14457	BECN1	P53355	DAPK1	S295	R292H	292	Missense	distal	-3	no	9.020	4.389	EPSD	TCGA;ICGC	8.849	Loss
CAMK_DAPK_DAPK_DAPK1_ST	Q14457	BECN1	P53355	DAPK1	S337	T343R	343	Missense	distal	6	no	9.714	7.841	EPSD	TCGA;ICGC;COSMIC	8.849	Loss
CAMK_DAPK_DAPK_DAPK1_ST	Q14457	BECN1	P53355	DAPK1	S337	P332L	332	Missense	distal	-5	no	9.714	9.980	EPSD	TCGA;ICGC;COSMIC	8.849	Up-regulation
CAMK_DAPK_DAPK_DAPK1_ST	Q14457	BECN1	P53355	DAPK1	T417	G411S	411	Missense	distal	-6	no	8.495	10.387	EPSD	TCGA;ICGC;COSMIC	8.849	Gain
CAMK_DAPK_DAPK_DAPK1_ST	P04637	TP53	P53355	DAPK1	S46	D48N	48	Missense	proximal	2	no	10.502	10.871	EPSD	TCGA;ICGC;COSMIC;GDSC;CCLE	8.849	Up-regulation
CAMK_DAPK_DAPK_DAPK1_ST	P04637	TP53	P53355	DAPK1	S269	R273C	273	Missense	distal	4	no	15.697	15.055	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC;GDSC;CCLE	8.849	Down-regulation
CAMK_DAPK_DAPK_DAPK1_ST	P04637	TP53	P53355	DAPK1	S269	C275S	275	Missense	distal	6	no	15.697	13.507	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	8.849	Down-regulation
CAMK_DAPK_DAPK_DAPK1_ST	P04637	TP53	P53355	DAPK1	S269	R273L	273	Missense	distal	4	no	15.697	16.292	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC;GDSC;CCLE	8.849	Up-regulation
CAMK_DAPK_DAPK_DAPK1_ST	P04637	TP53	P53355	DAPK1	S269	E271K	271	Missense	proximal	2	no	15.697	15.381	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC;GDSC;CCLE	8.849	Down-regulation
CAMK_DAPK_DAPK_DAPK1_ST	P04637	TP53	P53355	DAPK1	S269	C275Y	275	Missense	distal	6	no	15.697	14.219	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC;GDSC;CCLE	8.849	Down-regulation
CAMK_DAPK_DAPK_DAPK1_ST	P04637	TP53	P53355	DAPK1	S269	R273S	273	Missense	distal	4	no	15.697	16.308	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	8.849	Up-regulation
CAMK_DAPK_DAPK_DAPK1_ST	P04637	TP53	P53355	DAPK1	S269	E271Q	271	Missense	proximal	2	no	15.697	15.906	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	8.849	Up-regulation
CAMK_DAPK_DAPK_DAPK1_ST	P04637	TP53	P53355	DAPK1	S269	L265P	265	Missense	distal	-4	no	15.697	15.636	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC;GDSC;CCLE	8.849	Down-regulation
CAMK_DAPK_DAPK_DAPK1_ST	P04637	TP53	P53355	DAPK1	S269	V272M	272	Missense	distal	3	no	15.697	15.129	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC;GDSC;CCLE	8.849	Down-regulation
CAMK_DAPK_DAPK_DAPK1_ST	P04637	TP53	P53355	DAPK1	S269	G266E	266	Missense	distal	-3	no	15.697	17.045	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC;GDSC;CCLE	8.849	Up-regulation
CAMK_DAPK_DAPK_DAPK1_ST	P04637	TP53	P53355	DAPK1	S269	R273P	273	Missense	distal	4	no	15.697	15.633	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	8.849	Down-regulation
CAMK_DAPK_DAPK_DAPK1_ST	P04637	TP53	P53355	DAPK1	S269	F270I	270	Missense	proximal	1	no	15.697	15.772	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	8.849	Up-regulation
CAMK_DAPK_DAPK_DAPK1_ST	P04637	TP53	P53355	DAPK1	S269	R273H	273	Missense	distal	4	no	15.697	17.020	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC;GDSC;CCLE	8.849	Up-regulation
CAMK_DAPK_DAPK_DAPK1_ST	P04637	TP53	P53355	DAPK1	S269	A276P	276	Missense	distal	7	no	15.697	14.939	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	8.849	Down-regulation
CAMK_DAPK_DAPK_DAPK1_ST	P04637	TP53	P53355	DAPK1	S269	V272L	272	Missense	distal	3	no	15.697	14.659	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC;GDSC;CCLE	8.849	Down-regulation
CAMK_DAPK_DAPK_DAPK1_ST	P04637	TP53	P53355	DAPK1	S269	V274D	274	Missense	distal	5	no	15.697	15.799	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC;CCLE	8.849	Up-regulation
CAMK_DAPK_DAPK_DAPK1_ST	P04637	TP53	P53355	DAPK1	S269	G266V	266	Missense	distal	-3	no	15.697	13.678	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC;GDSC;CCLE	8.849	Down-regulation
CAMK_DAPK_DAPK_DAPK1_ST	P04637	TP53	P53355	DAPK1	S269	R267L	267	Missense	proximal	-2	no	15.697	14.181	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC;GDSC;CCLE	8.849	Down-regulation
CAMK_DAPK_DAPK_DAPK1_ST	P04637	TP53	P53355	DAPK1	S269	R267W	267	Missense	proximal	-2	no	15.697	13.045	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC;GDSC;CCLE	8.849	Down-regulation
CAMK_DAPK_DAPK_DAPK1_ST	P04637	TP53	P53355	DAPK1	S269	R267Q	267	Missense	proximal	-2	no	15.697	13.536	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC;CCLE	8.849	Down-regulation
CAMK_DAPK_DAPK_DAPK1_ST	P04637	TP53	P53355	DAPK1	S269	C275F	275	Missense	distal	6	no	15.697	14.336	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC;GDSC;CCLE	8.849	Down-regulation
CAMK_DAPK_DAPK_DAPK1_ST	P04637	TP53	P53355	DAPK1	S269	V274G	274	Missense	distal	5	no	15.697	15.299	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC;CCLE	8.849	Down-regulation
CAMK_DAPK_DAPK_DAPK1_ST	P04637	TP53	P53355	DAPK1	S269	V274L	274	Missense	distal	5	no	15.697	15.405	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	8.849	Down-regulation
CAMK_DAPK_DAPK_DAPK1_ST	P04637	TP53	P53355	DAPK1	S269	G266R	266	Missense	distal	-3	no	15.697	20.344	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC;GDSC;CCLE	8.849	Up-regulation
CAMK_DAPK_DAPK_DAPK1_ST	P04637	TP53	P53355	DAPK1	S269	R267P	267	Missense	proximal	-2	no	15.697	11.219	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC;GDSC;CCLE	8.849	Down-regulation
CAMK_DAPK_DAPK_DAPK1_ST	P04637	TP53	P53355	DAPK1	S269	A276D	276	Missense	distal	7	no	15.697	15.236	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	8.849	Down-regulation
CAMK_DAPK_DAPK_DAPK1_ST	P04637	TP53	P53355	DAPK1	S269	L265R	265	Missense	distal	-4	no	15.697	15.977	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	8.849	Up-regulation
CAMK_DAPK_DAPK_DAPK1_ST	P04637	TP53	P53355	DAPK1	S269	R267G	267	Missense	proximal	-2	no	15.697	12.796	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	8.849	Down-regulation
CAMK_DAPK_DAPK_DAPK1_ST	P04637	TP53	P53355	DAPK1	S269	F270C	270	Missense	proximal	1	no	15.697	16.208	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	8.849	Up-regulation
CAMK_DAPK_DAPK_DAPK1_ST	P04637	TP53	P53355	DAPK1	S269	E271V	271	Missense	proximal	2	no	15.697	16.147	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	8.849	Up-regulation
CAMK_DAPK_DAPK_DAPK1_ST	P04637	TP53	P53355	DAPK1	S269	G262V	262	Missense	distal	-7	no	15.697	15.965	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC;GDSC;CCLE	8.849	Up-regulation
CAMK_DAPK_DAPK_DAPK1_ST	P04637	TP53	P53355	DAPK1	S269	V274F	274	Missense	distal	5	no	15.697	14.717	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC;GDSC;CCLE	8.849	Down-regulation
CAMK_DAPK_DAPK_DAPK1_ST	P04637	TP53	P53355	DAPK1	S269	F270S	270	Missense	proximal	1	no	15.697	15.185	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	8.849	Down-regulation
CAMK_DAPK_DAPK_DAPK1_ST	P04637	TP53	P53355	DAPK1	S269	C275R	275	Missense	distal	6	no	15.697	13.775	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	8.849	Down-regulation
CAMK_DAPK_DAPK_DAPK1_ST	P04637	TP53	P53355	DAPK1	S269	C275G	275	Missense	distal	6	no	15.697	14.742	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC;GDSC;CCLE	8.849	Down-regulation
CAMK_DAPK_DAPK_DAPK1_ST	P04637	TP53	P53355	DAPK1	S269	A276G	276	Missense	distal	7	no	15.697	15.069	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	8.849	Down-regulation
CAMK_DAPK_DAPK_DAPK1_ST	P04637	TP53	P53355	DAPK1	S269	V272G	272	Missense	distal	3	no	15.697	16.064	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	8.849	Up-regulation
CAMK_DAPK_DAPK_DAPK1_ST	P04637	TP53	P53355	DAPK1	S269	R273G	273	Missense	distal	4	no	15.697	15.415	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	8.849	Down-regulation
CAMK_DAPK_DAPK_DAPK1_ST	P04637	TP53	P53355	DAPK1	S269	F270V	270	Missense	proximal	1	no	15.697	15.280	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	8.849	Down-regulation
CAMK_DAPK_DAPK_DAPK1_ST	P04637	TP53	P53355	DAPK1	S269	C275W	275	Missense	distal	6	no	15.697	14.338	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	8.849	Down-regulation
CAMK_DAPK_DAPK_DAPK1_ST	P04637	TP53	P53355	DAPK1	S269	V272A	272	Missense	distal	3	no	15.697	15.861	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	8.849	Up-regulation
CAMK_DAPK_DAPK_DAPK1_ST	P04637	TP53	P53355	DAPK1	S269	F270L	270	Missense	proximal	1	no	15.697	15.644	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	8.849	Down-regulation
CAMK_DAPK_DAPK_DAPK1_ST	P04637	TP53	P53355	DAPK1	T312	S315C	315	Missense	distal	3	no	7.745	9.982	EPSD	TCGA;ICGC;COSMIC	8.849	Gain
CAMK_DAPK_DAPK_DAPK1_ST	P04637	TP53	P53355	DAPK1	S371	S376C	376	Missense	distal	5	no	8.890	10.009	EPSD	TCGA;ICGC;COSMIC	8.849	Up-regulation
CAMK_DAPK_DAPK_DAPK1_ST	P04637	TP53	P53355	DAPK1	S371	Q375K	375	Missense	distal	4	no	8.890	8.694	EPSD	TCGA;ICGC;COSMIC	8.849	Loss
CAMK_DAPK_DAPK_DAPK1_ST	P04637	TP53	P53355	DAPK1	S376	S376C	376	Missense	central	0	yes	9.368	0.000	EPSD	TCGA;ICGC;COSMIC	8.849	Loss
CAMK_DAPK_DAPK_DAPK1_ST	P04637	TP53	P53355	DAPK1	S376	Q375K	375	Missense	proximal	-1	no	9.368	8.991	EPSD	TCGA;ICGC;COSMIC	8.849	Down-regulation
CAMK_DAPK_DAPK_DAPK1_ST	Q13526	PIN1	P53355	DAPK1	S71	S71L	71	Missense	central	0	yes	16.503	0.000	PhosphoSitePlus	TCGA;ICGC;COSMIC	8.849	Loss
CAMK_DAPK_DAPK_DAPK1_ST	Q13526	PIN1	P53355	DAPK1	S98	S105F	105	Missense	distal	7	no	9.643	8.761	EPSD	TCGA;ICGC;COSMIC	8.849	Loss
CAMK_DAPK_DAPK_DAPK1_ST	Q13526	PIN1	P53355	DAPK1	S98	E104K	104	Missense	distal	6	no	9.643	9.751	EPSD	TCGA;ICGC;COSMIC	8.849	Up-regulation
CAMK_DAPK_DAPK_DAPK1_ST	Q13526	PIN1	P53355	DAPK1	S111	S105F	105	Missense	distal	-6	no	9.084	6.990	EPSD	TCGA;ICGC;COSMIC	8.849	Loss
CAMK_DAPK_DAPK_DAPK1_ST	Q13526	PIN1	P53355	DAPK1	S111	D112N	112	Missense	proximal	1	no	9.084	9.165	EPSD	TCGA;ICGC;COSMIC	8.849	Up-regulation
CAMK_DAPK_DAPK_DAPK1_ST	Q13526	PIN1	P53355	DAPK1	S111	E104K	104	Missense	distal	-7	no	9.084	9.603	EPSD	TCGA;ICGC;COSMIC	8.849	Up-regulation
CAMK_DAPK_DAPK_DAPK1_ST	Q13526	PIN1	P53355	DAPK1	S111	Q109R	109	Missense	proximal	-2	no	9.084	11.245	EPSD	TCGA;ICGC	8.849	Up-regulation
CAMK_DAPK_DAPK_DAPK1_ST	Q13526	PIN1	P53355	DAPK1	S114	D112N	112	Missense	proximal	-2	no	9.285	10.921	EPSD	TCGA;ICGC;COSMIC	8.849	Up-regulation
CAMK_DAPK_DAPK_DAPK1_ST	Q13526	PIN1	P53355	DAPK1	S114	Q109R	109	Missense	distal	-5	no	9.285	9.441	EPSD	TCGA;ICGC	8.849	Up-regulation
CAMK_DAPK_DAPK_DAPK1_ST	Q13526	PIN1	P53355	DAPK1	S147	E145K	145	Missense	proximal	-2	no	7.229	9.477	EPSD	TCGA;ICGC;COSMIC	8.849	Gain
CAMK_DAPK_DAPK_DAPK1_ST	P09493	TPM1	P53355	DAPK1	T108	R101C	101	Missense	distal	-7	no	10.333	12.255	EPSD	TCGA;ICGC;COSMIC	8.849	Up-regulation
CAMK_DAPK_DAPK_DAPK1_ST	P09493	TPM1	P53355	DAPK1	S271	D275V	275	Missense	distal	4	no	8.027	8.922	EPSD	TCGA;COSMIC	8.849	Gain
CAMK_DAPK_DAPK_DAPK1_ST	Q13224	GRIN2B	P53355	DAPK1	S770	S770Y	770	Missense	central	0	yes	9.388	0.000	EPSD	TCGA;COSMIC	8.849	Loss
CAMK_DAPK_DAPK_DAPK1_ST	Q13224	GRIN2B	P53355	DAPK1	S770	G771V	771	Missense	proximal	1	no	9.388	8.789	EPSD	TCGA;ICGC;COSMIC	8.849	Loss
CAMK_DAPK_DAPK_DAPK1_ST	Q13224	GRIN2B	P53355	DAPK1	S770	D769N	769	Missense	proximal	-1	no	9.388	9.974	EPSD	TCGA;ICGC;COSMIC	8.849	Up-regulation
CAMK_DAPK_DAPK_DAPK1_ST	Q13224	GRIN2B	P53355	DAPK1	S865	P858H	858	Missense	distal	-7	no	9.141	9.892	EPSD	TCGA;ICGC;COSMIC	8.849	Up-regulation
CAMK_DAPK_DAPK_DAPK1_ST	Q13224	GRIN2B	P53355	DAPK1	S882	A876V	876	Missense	distal	-6	no	8.702	8.899	EPSD	TCGA;ICGC;COSMIC	8.849	Gain
CAMK_DAPK_DAPK_DAPK1_ST	Q13224	GRIN2B	P53355	DAPK1	T894	M891I	891	Missense	distal	-3	no	9.847	7.408	EPSD	TCGA;ICGC;COSMIC	8.849	Loss
CAMK_DAPK_DAPK_DAPK1_ST	Q13224	GRIN2B	P53355	DAPK1	T894	R900G	900	Missense	distal	6	no	9.847	10.814	EPSD	TCGA;ICGC;COSMIC	8.849	Up-regulation
CAMK_DAPK_DAPK_DAPK1_ST	Q13224	GRIN2B	P53355	DAPK1	T894	M891T	891	Missense	distal	-3	no	9.847	9.746	EPSD	TCGA;ICGC;COSMIC	8.849	Down-regulation
CAMK_DAPK_DAPK_DAPK1_ST	Q13224	GRIN2B	P53355	DAPK1	T894	S896F	896	Missense	proximal	2	no	9.847	9.635	EPSD	TCGA;ICGC;COSMIC	8.849	Down-regulation
CAMK_DAPK_DAPK_DAPK1_ST	Q13224	GRIN2B	P53355	DAPK1	T894	R900C	900	Missense	distal	6	no	9.847	11.769	EPSD	TCGA;ICGC;COSMIC	8.849	Up-regulation
CAMK_DAPK_DAPK_DAPK1_ST	Q13224	GRIN2B	P53355	DAPK1	S930	E928K	928	Missense	proximal	-2	no	7.136	9.384	EPSD	TCGA;ICGC;COSMIC	8.849	Gain
CAMK_DAPK_DAPK_DAPK1_ST	Q13224	GRIN2B	P53355	DAPK1	S1166	R1164C	1164	Missense	proximal	-2	no	9.263	5.288	EPSD	TCGA;ICGC;COSMIC	8.849	Loss
CAMK_DAPK_DAPK_DAPK1_ST	Q13224	GRIN2B	P53355	DAPK1	S1166	G1170R	1170	Missense	distal	4	no	9.263	9.545	EPSD	TCGA;ICGC;COSMIC	8.849	Up-regulation
CAMK_DAPK_DAPK_DAPK1_ST	Q13224	GRIN2B	P53355	DAPK1	S1166	S1168R	1168	Missense	proximal	2	no	9.263	9.218	EPSD	TCGA;ICGC;COSMIC	8.849	Down-regulation
CAMK_DAPK_DAPK_DAPK1_ST	Q13224	GRIN2B	P53355	DAPK1	S1166	G1169R	1169	Missense	distal	3	no	9.263	7.985	EPSD	TCGA;ICGC;COSMIC;CCLE	8.849	Loss
CAMK_DAPK_DAPK_DAPK1_ST	Q13224	GRIN2B	P53355	DAPK1	S1166	G1170E	1170	Missense	distal	4	no	9.263	9.133	EPSD	TCGA;ICGC;COSMIC	8.849	Down-regulation
CAMK_DAPK_DAPK_DAPK1_ST	Q13224	GRIN2B	P53355	DAPK1	S1166	D1161N	1161	Missense	distal	-5	no	9.263	9.445	EPSD	TCGA;ICGC;COSMIC	8.849	Up-regulation
CAMK_DAPK_DAPK_DAPK1_ST	Q13224	GRIN2B	P53355	DAPK1	T1183	V1189M	1189	Missense	distal	6	no	8.433	9.056	EPSD	TCGA;ICGC;COSMIC	8.849	Gain
CAMK_DAPK_DAPK_DAPK1_ST	Q13224	GRIN2B	P53355	DAPK1	S1303	R1299H	1299	Missense	distal	-4	no	18.959	18.793	PhosphoSitePlus	TCGA;ICGC;COSMIC;CCLE	8.849	Down-regulation
CAMK_DAPK_DAPK_DAPK1_ST	Q13224	GRIN2B	P53355	DAPK1	S1303	R1300Q	1300	Missense	distal	-3	no	18.959	14.746	PhosphoSitePlus	TCGA;ICGC;COSMIC	8.849	Down-regulation
CAMK_DAPK_DAPK_DAPK1_ST	Q13224	GRIN2B	P53355	DAPK1	S1303	R1299C	1299	Missense	distal	-4	no	18.959	18.622	PhosphoSitePlus	TCGA;ICGC;COSMIC;GDSC;CCLE	8.849	Down-regulation
CAMK_DAPK_DAPK_DAPK1_ST	Q13224	GRIN2B	P53355	DAPK1	S1303	N1296T	1296	Missense	distal	-7	no	18.959	20.089	PhosphoSitePlus	TCGA;ICGC	8.849	Up-regulation
CAMK_DAPK_DAPK_DAPK1_ST	Q13224	GRIN2B	P53355	DAPK1	S1323	A1318G	1318	Missense	distal	-5	no	10.042	10.055	EPSD	TCGA;ICGC;COSMIC	8.849	Up-regulation
CAMK_DAPK_DAPK_DAPK1_ST	Q13224	GRIN2B	P53355	DAPK1	S1323	R1320H	1320	Missense	distal	-3	no	10.042	5.412	EPSD	TCGA;ICGC;COSMIC	8.849	Loss
CAMK_DAPK_DAPK_DAPK1_ST	Q13224	GRIN2B	P53355	DAPK1	S1469	Y1474C	1474	Missense	distal	5	no	9.651	10.482	EPSD	TCGA;ICGC;COSMIC	8.849	Up-regulation
CAMK_DAPK_DAPK_DAPK1_ST	Q13224	GRIN2B	P53355	DAPK1	S1469	A1464V	1464	Missense	distal	-5	no	9.651	9.625	EPSD	TCGA;ICGC;COSMIC	8.849	Down-regulation
CAMK_DAPK_DAPK_DAPK1_ST	Q13224	GRIN2B	P53355	DAPK1	S1469	E1475K	1475	Missense	distal	6	no	9.651	9.759	EPSD	TCGA;ICGC;COSMIC	8.849	Up-regulation
CAMK_DAPK_DAPK_DAPK1_ST	Q13224	GRIN2B	P53355	DAPK1	S1469	G1471A	1471	Missense	proximal	2	no	9.651	9.534	EPSD	TCGA	8.849	Down-regulation
CAMK_DAPK_DAPK_DAPK1_ST	Q13224	GRIN2B	P53355	DAPK1	S1469	F1465C	1465	Missense	distal	-4	no	9.651	9.579	EPSD	TCGA;ICGC;COSMIC	8.849	Down-regulation
CAMK_DAPK_DAPK_DAPK1_ST	Q13224	GRIN2B	P53355	DAPK1	S1469	H1472R	1472	Missense	distal	3	no	9.651	9.919	EPSD	TCGA;ICGC;COSMIC	8.849	Up-regulation
CAMK_PKD_PRKD1_ST	Q8WUI4	HDAC7	Q15139	PRKD1	S573	S573F	573	Missense	central	0	yes	8.292	0.000	EPSD	TCGA;COSMIC	4.507	Loss
CAMK_PKD_PRKD1_ST	Q8WUI4	HDAC7	Q15139	PRKD1	S903	P905T	905	Missense	proximal	2	no	6.132	6.106	EPSD	TCGA	4.507	Down-regulation
CAMK_PKD_PRKD1_ST	P35670	ATP7B	Q15139	PRKD1	S23	R27C	27	Missense	distal	4	no	4.625	4.636	EPSD	TCGA;ICGC;COSMIC	4.507	Up-regulation
CAMK_PKD_PRKD1_ST	P35670	ATP7B	Q15139	PRKD1	S23	S20F	20	Missense	distal	-3	no	4.625	3.885	EPSD	TCGA;ICGC;COSMIC	4.507	Loss
CAMK_PKD_PRKD1_ST	P35670	ATP7B	Q15139	PRKD1	S229	R234K	234	Missense	distal	5	no	6.288	6.233	EPSD	TCGA;ICGC;COSMIC	4.507	Down-regulation
CAMK_PKD_PRKD1_ST	P35670	ATP7B	Q15139	PRKD1	S229	R234I	234	Missense	distal	5	no	6.288	6.206	EPSD	TCGA;ICGC;COSMIC;GDSC;CCLE	4.507	Down-regulation
CAMK_PKD_PRKD1_ST	P35670	ATP7B	Q15139	PRKD1	S229	R226W	226	Missense	distal	-3	no	6.288	0.916	EPSD	TCGA;ICGC;COSMIC	4.507	Loss
CAMK_PKD_PRKD1_ST	P35670	ATP7B	Q15139	PRKD1	S342	S343Y	343	Missense	proximal	1	no	7.178	7.177	EPSD	TCGA;ICGC;COSMIC	4.507	Down-regulation
CAMK_PKD_PRKD1_ST	P35670	ATP7B	Q15139	PRKD1	S342	R339M	339	Missense	distal	-3	no	7.178	3.056	EPSD	TCGA;ICGC;COSMIC	4.507	Loss
CAMK_PKD_PRKD1_ST	P35670	ATP7B	Q15139	PRKD1	S342	P349S	349	Missense	distal	7	no	7.178	7.179	EPSD	TCGA;ICGC;COSMIC	4.507	Up-regulation
CAMK_PKD_PRKD1_ST	P35670	ATP7B	Q15139	PRKD1	S342	S348F	348	Missense	distal	6	no	7.178	7.226	EPSD	TCGA;ICGC;COSMIC	4.507	Up-regulation
CAMK_PKD_PRKD1_ST	P35670	ATP7B	Q15139	PRKD1	S1121	P1119H	1119	Missense	proximal	-2	no	7.938	8.158	EPSD;PhosphoSitePlus	TCGA;COSMIC	4.507	Up-regulation
CAMK_PKD_PRKD1_ST	P35670	ATP7B	Q15139	PRKD1	S1121	R1118H	1118	Missense	distal	-3	no	7.938	3.951	EPSD;PhosphoSitePlus	TCGA;COSMIC	4.507	Loss
CAMK_PKD_PRKD1_ST	P35670	ATP7B	Q15139	PRKD1	S1121	R1118L	1118	Missense	distal	-3	no	7.938	3.010	EPSD;PhosphoSitePlus	TCGA;COSMIC	4.507	Loss
CAMK_PKD_PRKD1_ST	O15273	TCAP	Q15139	PRKD1	S157	S159F	159	Missense	proximal	2	no	9.788	9.642	PhosphoSitePlus;EPSD	TCGA;COSMIC	4.507	Down-regulation
CAMK_PKD_PRKD1_ST	O15273	TCAP	Q15139	PRKD1	S157	R154C	154	Missense	distal	-3	no	9.788	5.691	PhosphoSitePlus;EPSD	TCGA;COSMIC	4.507	Down-regulation
CAMK_PKD_PRKD1_ST	O15273	TCAP	Q15139	PRKD1	S157	S155P	155	Missense	proximal	-2	no	9.788	9.466	PhosphoSitePlus;EPSD	TCGA;COSMIC	4.507	Down-regulation
CAMK_PKD_PRKD1_ST	O15273	TCAP	Q15139	PRKD1	S157	M160T	160	Missense	distal	3	no	9.788	9.778	PhosphoSitePlus;EPSD	TCGA;COSMIC	4.507	Down-regulation
CAMK_PKD_PRKD1_ST	O15273	TCAP	Q15139	PRKD1	S161	S159F	159	Missense	proximal	-2	no	10.113	8.559	EPSD;PhosphoSitePlus	TCGA;COSMIC	4.507	Down-regulation
CAMK_PKD_PRKD1_ST	O15273	TCAP	Q15139	PRKD1	S161	R154C	154	Missense	distal	-7	no	10.113	9.660	EPSD;PhosphoSitePlus	TCGA;COSMIC	4.507	Down-regulation
CAMK_PKD_PRKD1_ST	O15273	TCAP	Q15139	PRKD1	S161	S155P	155	Missense	distal	-6	no	10.113	10.104	EPSD;PhosphoSitePlus	TCGA;COSMIC	4.507	Down-regulation
CAMK_PKD_PRKD1_ST	O15273	TCAP	Q15139	PRKD1	S161	M160T	160	Missense	proximal	-1	no	10.113	10.035	EPSD;PhosphoSitePlus	TCGA;COSMIC	4.507	Down-regulation
CAMK_PKD_PRKD1_ST	P35222	CTNNB1	Q15139	PRKD1	S37	G34R	34	Missense	distal	-3	no	-0.100	4.666	EPSD	TCGA;COSMIC	4.507	Gain
CAMK_PKD_PRKD1_ST	P35222	CTNNB1	Q15139	PRKD1	S45	S45F	45	Missense	central	0	yes	5.138	0.000	EPSD	TCGA;COSMIC;GDSC;CCLE	4.507	Loss
CAMK_PKD_PRKD1_ST	P35222	CTNNB1	Q15139	PRKD1	S45	S45P	45	Missense	central	0	yes	5.138	0.000	EPSD	TCGA;COSMIC;CCLE	4.507	Loss
CAMK_PKD_PRKD1_ST	P35222	CTNNB1	Q15139	PRKD1	S45	T41A	41	Missense	distal	-4	no	5.138	5.143	EPSD	TCGA;COSMIC;GDSC;CCLE	4.507	Up-regulation
CAMK_PKD_PRKD1_ST	P35222	CTNNB1	Q15139	PRKD1	S45	T41I	41	Missense	distal	-4	no	5.138	5.135	EPSD	TCGA;COSMIC	4.507	Down-regulation
CAMK_PKD_PRKD1_ST	P35222	CTNNB1	Q15139	PRKD1	S45	S45Y	45	Missense	central	0	yes	5.138	0.000	EPSD	TCGA;COSMIC	4.507	Loss
CAMK_PKD_PRKD1_ST	P35222	CTNNB1	Q15139	PRKD1	S45	T41N	41	Missense	distal	-4	no	5.138	5.135	EPSD	TCGA;COSMIC	4.507	Down-regulation
CAMK_PKD_PRKD1_ST	P35222	CTNNB1	Q15139	PRKD1	S45	S45C	45	Missense	central	0	yes	5.138	0.000	EPSD	TCGA;COSMIC;GDSC;CCLE	4.507	Loss
CAMK_PKD_PRKD1_ST	P35222	CTNNB1	Q15139	PRKD1	T332	E334A	334	Missense	proximal	2	no	6.119	6.205	EPSD	TCGA;COSMIC	4.507	Up-regulation
CAMK_PKD_PRKD1_ST	P35222	CTNNB1	Q15139	PRKD1	T332	K335T	335	Missense	distal	3	no	6.119	6.113	EPSD	TCGA;COSMIC	4.507	Down-regulation
CAMK_PKD_PRKD1_ST	P35222	CTNNB1	Q15139	PRKD1	T332	K335I	335	Missense	distal	3	no	6.119	6.113	EPSD	TCGA;COSMIC	4.507	Down-regulation
CAMK_PKD_PRKD1_ST	P35222	CTNNB1	Q15139	PRKD1	T332	M328I	328	Missense	distal	-4	no	6.119	6.115	EPSD	TCGA;COSMIC	4.507	Down-regulation
CAMK_PKD_PRKD1_ST	P35222	CTNNB1	Q15139	PRKD1	T332	E334K	334	Missense	proximal	2	no	6.119	6.137	EPSD	TCGA;COSMIC;GDSC;CCLE	4.507	Up-regulation
CAMK_PKD_PRKD1_ST	P35222	CTNNB1	Q15139	PRKD1	T332	L336P	336	Missense	distal	4	no	6.119	6.122	EPSD	TCGA;COSMIC	4.507	Up-regulation
CAMK_PKD_PRKD1_ST	P35222	CTNNB1	Q15139	PRKD1	T472	R469H	469	Missense	distal	-3	no	6.729	2.743	EPSD	TCGA;COSMIC	4.507	Loss
CAMK_PKD_PRKD1_ST	P35222	CTNNB1	Q15139	PRKD1	T472	R474Q	474	Missense	proximal	2	no	6.729	6.712	EPSD	TCGA;GDSC;CCLE	4.507	Down-regulation
CAMK_PKD_PRKD1_ST	P35222	CTNNB1	Q15139	PRKD1	S473	R469H	469	Missense	distal	-4	no	4.951	4.946	EPSD	TCGA;COSMIC	4.507	Down-regulation
CAMK_PKD_PRKD1_ST	P35222	CTNNB1	Q15139	PRKD1	S675	S681F	681	Missense	distal	6	no	5.030	5.077	EPSD	TCGA	4.507	Up-regulation
CAMK_PKD_PRKD1_ST	Q8WYL5	SSH1	Q15139	PRKD1	S237	S237F	237	Missense	central	0	yes	6.430	0.000	EPSD	TCGA;ICGC;COSMIC	4.507	Loss
CAMK_PKD_PRKD1_ST	Q8WYL5	SSH1	Q15139	PRKD1	S237	T233M	233	Missense	distal	-4	no	6.430	6.432	EPSD	TCGA;ICGC;COSMIC	4.507	Up-regulation
CAMK_PKD_PRKD1_ST	Q8WYL5	SSH1	Q15139	PRKD1	S237	R234Q	234	Missense	distal	-3	no	6.430	2.018	EPSD	TCGA;ICGC;COSMIC	4.507	Loss
CAMK_PKD_PRKD1_ST	Q8WYL5	SSH1	Q15139	PRKD1	S402	R399H	399	Missense	distal	-3	no	8.076	4.090	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	4.507	Loss
CAMK_PKD_PRKD1_ST	Q8WYL5	SSH1	Q15139	PRKD1	S402	V397L	397	Missense	distal	-5	no	8.076	9.610	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	4.507	Up-regulation
CAMK_PKD_PRKD1_ST	Q8WYL5	SSH1	Q15139	PRKD1	S402	S400L	400	Missense	proximal	-2	no	8.076	6.812	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	4.507	Down-regulation
CAMK_PKD_PRKD1_ST	Q8WYL5	SSH1	Q15139	PRKD1	T430	I429V	429	Missense	proximal	-1	no	4.515	4.509	EPSD	TCGA	4.507	Down-regulation
CAMK_PKD_PRKD1_ST	Q8WYL5	SSH1	Q15139	PRKD1	T430	R427C	427	Missense	distal	-3	no	4.515	0.418	EPSD	TCGA;ICGC;COSMIC	4.507	Loss
CAMK_PKD_PRKD1_ST	Q8WYL5	SSH1	Q15139	PRKD1	S441	Y443C	443	Missense	proximal	2	no	6.063	6.177	EPSD	TCGA;ICGC;COSMIC	4.507	Up-regulation
CAMK_PKD_PRKD1_ST	Q8WYL5	SSH1	Q15139	PRKD1	S515	F511L	511	Missense	distal	-4	no	9.595	9.598	EPSD	TCGA;ICGC	4.507	Up-regulation
CAMK_PKD_PRKD1_ST	Q8WYL5	SSH1	Q15139	PRKD1	S515	P508T	508	Missense	distal	-7	no	9.595	9.539	EPSD	TCGA;ICGC;COSMIC	4.507	Down-regulation
CAMK_PKD_PRKD1_ST	Q8WYL5	SSH1	Q15139	PRKD1	S583	G579S	579	Missense	distal	-4	no	7.071	7.080	EPSD	TCGA;ICGC;COSMIC	4.507	Up-regulation
CAMK_PKD_PRKD1_ST	Q8WYL5	SSH1	Q15139	PRKD1	S583	P577S	577	Missense	distal	-6	no	7.071	7.081	EPSD	TCGA;ICGC;COSMIC	4.507	Up-regulation
CAMK_PKD_PRKD1_ST	Q8WYL5	SSH1	Q15139	PRKD1	S739	S744F	744	Missense	distal	5	no	6.389	6.277	EPSD	TCGA;ICGC	4.507	Down-regulation
CAMK_PKD_PRKD1_ST	Q8WYL5	SSH1	Q15139	PRKD1	S777	K774R	774	Missense	distal	-3	no	4.194	6.866	EPSD	TCGA;ICGC;COSMIC	4.507	Gain
CAMK_PKD_PRKD1_ST	Q8WYL5	SSH1	Q15139	PRKD1	T826	R831W	831	Missense	distal	5	no	8.625	8.506	EPSD	TCGA;ICGC;COSMIC	4.507	Down-regulation
CAMK_PKD_PRKD1_ST	Q8WYL5	SSH1	Q15139	PRKD1	S834	P841S	841	Missense	distal	7	no	9.355	9.356	EPSD	TCGA;ICGC;COSMIC	4.507	Up-regulation
CAMK_PKD_PRKD1_ST	Q8WYL5	SSH1	Q15139	PRKD1	S834	R831W	831	Missense	distal	-3	no	9.355	3.983	EPSD	TCGA;ICGC;COSMIC	4.507	Loss
CAMK_PKD_PRKD1_ST	Q8WYL5	SSH1	Q15139	PRKD1	S910	H907L	907	Missense	distal	-3	no	4.677	3.736	EPSD	TCGA;ICGC	4.507	Loss
CAMK_PKD_PRKD1_ST	Q8WYL5	SSH1	Q15139	PRKD1	S910	R904C	904	Missense	distal	-6	no	4.677	4.657	EPSD	TCGA;ICGC;COSMIC	4.507	Down-regulation
CAMK_PKD_PRKD1_ST	Q8WYL5	SSH1	Q15139	PRKD1	S936	R934Q	934	Missense	proximal	-2	no	5.457	3.490	EPSD	TCGA;ICGC;COSMIC	4.507	Loss
CAMK_PKD_PRKD1_ST	Q8WYL5	SSH1	Q15139	PRKD1	S936	R934W	934	Missense	proximal	-2	no	5.457	1.994	EPSD	TCGA;ICGC;COSMIC	4.507	Loss
CAMK_PKD_PRKD1_ST	Q8WYL5	SSH1	Q15139	PRKD1	S936	S940N	940	Missense	distal	4	no	5.457	5.467	EPSD	TCGA;ICGC;COSMIC	4.507	Up-regulation
CAMK_PKD_PRKD1_ST	Q8WYL5	SSH1	Q15139	PRKD1	S937	R934Q	934	Missense	distal	-3	no	9.193	4.781	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	4.507	Down-regulation
CAMK_PKD_PRKD1_ST	Q8WYL5	SSH1	Q15139	PRKD1	S937	R934W	934	Missense	distal	-3	no	9.193	3.821	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	4.507	Loss
CAMK_PKD_PRKD1_ST	Q8WYL5	SSH1	Q15139	PRKD1	S937	S940N	940	Missense	distal	3	no	9.193	9.180	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	4.507	Down-regulation
CAMK_PKD_PRKD1_ST	Q8WYL5	SSH1	Q15139	PRKD1	S984	T989M	989	Missense	distal	5	no	5.357	5.390	EPSD	TCGA;ICGC;COSMIC	4.507	Up-regulation
CAMK_PKD_PRKD1_ST	Q8WYL5	SSH1	Q15139	PRKD1	S1044	S1044L	1044	Missense	central	0	yes	4.860	0.000	EPSD	TCGA;ICGC;COSMIC	4.507	Loss
CAMK_PKD_PRKD1_ST	Q8WYL5	SSH1	Q15139	PRKD1	S1044	P1043H	1043	Missense	proximal	-1	no	4.860	4.924	EPSD	TCGA;ICGC	4.507	Up-regulation
CAMK_PKD_PRKD1_ST	Q8WYL5	SSH1	Q15139	PRKD1	S1049	S1044L	1044	Missense	distal	-5	no	2.845	5.109	EPSD	TCGA;ICGC;COSMIC	4.507	Gain
CAMK_PKD_PRKD1_ST	Q92934	BAD	Q15139	PRKD1	S74	S71I	71	Missense	distal	-3	no	4.622	3.974	EPSD	TCGA;ICGC;COSMIC	4.507	Loss
CAMK_PKD_PRKD1_ST	Q92934	BAD	Q15139	PRKD1	S75	S71I	71	Missense	distal	-4	no	8.207	8.200	PhosphoSitePlus;EPSD	TCGA;ICGC;COSMIC	4.507	Down-regulation
CAMK_PKD_PRKD1_ST	Q92934	BAD	Q15139	PRKD1	S97	A100T	100	Missense	distal	3	no	6.387	6.368	EPSD	TCGA;ICGC;COSMIC	4.507	Down-regulation
CAMK_PKD_PRKD1_ST	Q92934	BAD	Q15139	PRKD1	S99	A100T	100	Missense	proximal	1	no	7.408	7.407	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	4.507	Down-regulation
CAMK_PKD_PRKD1_ST	Q92934	BAD	Q15139	PRKD1	S118	M117I	117	Missense	proximal	-1	no	7.427	7.324	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	4.507	Down-regulation
CAMK_PKD_PRKD1_ST	Q92934	BAD	Q15139	PRKD1	S134	R131H	131	Missense	distal	-3	no	10.798	6.812	EPSD	TCGA;ICGC;COSMIC	4.507	Down-regulation
CAMK_PKD_PRKD1_ST	Q92934	BAD	Q15139	PRKD1	S134	G136D	136	Missense	proximal	2	no	10.798	10.824	EPSD	TCGA;ICGC;COSMIC	4.507	Up-regulation
CAMK_PKD_PRKD1_ST	Q92934	BAD	Q15139	PRKD1	S134	S134I	134	Missense	central	0	yes	10.798	0.000	EPSD	TCGA	4.507	Loss
CAMK_PKD_PRKD1_ST	Q92934	BAD	Q15139	PRKD1	S164	G162V	162	Missense	proximal	-2	no	8.811	8.396	EPSD	TCGA;ICGC;COSMIC	4.507	Down-regulation
CAMK_PKD_PRKD1_ST	Q92934	BAD	Q15139	PRKD1	S164	S164F	164	Missense	central	0	yes	8.811	0.000	EPSD	TCGA;ICGC;COSMIC;GDSC;CCLE	4.507	Loss
CAMK_PKD_PRKD1_ST	Q92934	BAD	Q15139	PRKD1	S164	S167P	167	Missense	distal	3	no	8.811	8.800	EPSD	TCGA;COSMIC	4.507	Down-regulation
CAMK_PKD_PRKD1_ST	Q92934	BAD	Q15139	PRKD1	S164	S163N	163	Missense	proximal	-1	no	8.811	8.651	EPSD	TCGA;ICGC;COSMIC	4.507	Down-regulation
CAMK_PKD_PRKD1_ST	Q92934	BAD	Q15139	PRKD1	S164	G162E	162	Missense	proximal	-2	no	8.811	9.794	EPSD	TCGA;ICGC	4.507	Up-regulation
CAMK_PKD_PRKD1_ST	Q9UQL6	HDAC5	Q15139	PRKD1	T546	E551D	551	Missense	distal	5	no	8.050	7.989	EPSD	TCGA;ICGC;COSMIC	4.507	Down-regulation
CAMK_PKD_PRKD1_ST	Q96QB1	DLC1	Q15139	PRKD1	S354	R351W	351	Missense	distal	-3	no	5.871	0.498	EPSD	TCGA;ICGC;COSMIC;GDSC;CCLE	4.507	Loss
CAMK_PKD_PRKD1_ST	Q96QB1	DLC1	Q15139	PRKD1	S354	M355I	355	Missense	proximal	1	no	5.871	5.870	EPSD	TCGA;ICGC;COSMIC	4.507	Down-regulation
CAMK_PKD_PRKD1_ST	Q96QB1	DLC1	Q15139	PRKD1	S354	D348H	348	Missense	distal	-6	no	5.871	5.889	EPSD	TCGA;ICGC;COSMIC	4.507	Up-regulation
CAMK_PKD_PRKD1_ST	Q96QB1	DLC1	Q15139	PRKD1	S354	A350E	350	Missense	distal	-4	no	5.871	5.867	EPSD	TCGA;ICGC;COSMIC	4.507	Down-regulation
CAMK_PKD_PRKD1_ST	Q96QB1	DLC1	Q15139	PRKD1	S378	T382R	382	Missense	distal	4	no	6.214	6.197	EPSD	TCGA;ICGC;COSMIC	4.507	Down-regulation
CAMK_PKD_PRKD1_ST	Q96QB1	DLC1	Q15139	PRKD1	S378	L373I	373	Missense	distal	-5	no	6.214	4.557	EPSD	TCGA;ICGC;COSMIC	4.507	Down-regulation
CAMK_PKD_PRKD1_ST	Q96QB1	DLC1	Q15139	PRKD1	S378	A372T	372	Missense	distal	-6	no	6.214	6.193	EPSD	TCGA;ICGC;COSMIC	4.507	Down-regulation
CAMK_PKD_PRKD1_ST	Q96QB1	DLC1	Q15139	PRKD1	S523	I516M	516	Missense	distal	-7	no	6.164	6.371	EPSD	TCGA;COSMIC	4.507	Up-regulation
CAMK_PKD_PRKD1_ST	Q96QB1	DLC1	Q15139	PRKD1	S523	D525E	525	Missense	proximal	2	no	6.164	6.248	EPSD	TCGA;ICGC;COSMIC	4.507	Up-regulation
CAMK_PKD_PRKD1_ST	Q96QB1	DLC1	Q15139	PRKD1	S523	D529Y	529	Missense	distal	6	no	6.164	6.173	EPSD	TCGA;ICGC;COSMIC	4.507	Up-regulation
CAMK_PKD_PRKD1_ST	Q96QB1	DLC1	Q15139	PRKD1	S523	H519D	519	Missense	distal	-4	no	6.164	6.156	EPSD	TCGA;COSMIC	4.507	Down-regulation
CAMK_PKD_PRKD1_ST	Q96QB1	DLC1	Q15139	PRKD1	S548	E552Q	552	Missense	distal	4	no	6.637	6.629	EPSD	TCGA;COSMIC	4.507	Down-regulation
CAMK_PKD_PRKD1_ST	Q96QB1	DLC1	Q15139	PRKD1	S598	R595H	595	Missense	distal	-3	no	7.237	3.250	EPSD	TCGA;ICGC;COSMIC	4.507	Loss
CAMK_PKD_PRKD1_ST	Q96QB1	DLC1	Q15139	PRKD1	S598	R595C	595	Missense	distal	-3	no	7.237	3.140	EPSD	TCGA;COSMIC	4.507	Loss
CAMK_PKD_PRKD1_ST	Q96QB1	DLC1	Q15139	PRKD1	S598	S593F	593	Missense	distal	-5	no	7.237	6.348	EPSD	TCGA;COSMIC	4.507	Down-regulation
CAMK_PKD_PRKD1_ST	Q96QB1	DLC1	Q15139	PRKD1	S598	P604S	604	Missense	distal	6	no	7.237	7.217	EPSD	TCGA;COSMIC	4.507	Down-regulation
CAMK_PKD_PRKD1_ST	Q96QB1	DLC1	Q15139	PRKD1	S602	P604S	604	Missense	proximal	2	no	4.465	4.507	EPSD	TCGA;COSMIC	4.507	Gain
CAMK_PKD_PRKD1_ST	Q96QB1	DLC1	Q15139	PRKD1	S620	A614T	614	Missense	distal	-6	no	6.628	6.607	EPSD	TCGA;COSMIC	4.507	Down-regulation
CAMK_PKD_PRKD1_ST	Q96QB1	DLC1	Q15139	PRKD1	S620	V624I	624	Missense	distal	4	no	6.628	6.630	EPSD	TCGA;ICGC;COSMIC	4.507	Up-regulation
CAMK_PKD_PRKD1_ST	Q96QB1	DLC1	Q15139	PRKD1	S620	P616H	616	Missense	distal	-4	no	6.628	6.629	EPSD	TCGA;ICGC;COSMIC	4.507	Up-regulation
CAMK_PKD_PRKD1_ST	Q96QB1	DLC1	Q15139	PRKD1	S620	S620F	620	Missense	central	0	yes	6.628	0.000	EPSD	TCGA;COSMIC;GDSC;CCLE	4.507	Loss
CAMK_PKD_PRKD1_ST	Q96QB1	DLC1	Q15139	PRKD1	S620	R617Q	617	Missense	distal	-3	no	6.628	2.216	EPSD	TCGA;COSMIC	4.507	Loss
CAMK_PKD_PRKD1_ST	Q96QB1	DLC1	Q15139	PRKD1	S673	S679C	679	Missense	distal	6	no	9.600	9.624	EPSD	TCGA;COSMIC	4.507	Up-regulation
CAMK_PKD_PRKD1_ST	Q96QB1	DLC1	Q15139	PRKD1	S673	R670P	670	Missense	distal	-3	no	9.600	5.684	EPSD	TCGA;ICGC;COSMIC	4.507	Down-regulation
CAMK_PKD_PRKD1_ST	Q96QB1	DLC1	Q15139	PRKD1	S673	K677N	677	Missense	distal	4	no	9.600	9.603	EPSD	TCGA;COSMIC	4.507	Up-regulation
CAMK_PKD_PRKD1_ST	Q96QB1	DLC1	Q15139	PRKD1	S673	K675R	675	Missense	proximal	2	no	9.600	9.640	EPSD	TCGA	4.507	Up-regulation
CAMK_PKD_PRKD1_ST	Q96QB1	DLC1	Q15139	PRKD1	S733	T738S	738	Missense	distal	5	no	8.400	8.455	EPSD	TCGA;COSMIC	4.507	Up-regulation
CAMK_PKD_PRKD1_ST	Q96QB1	DLC1	Q15139	PRKD1	S735	T738S	738	Missense	distal	3	no	7.891	7.905	EPSD	TCGA;COSMIC	4.507	Up-regulation
CAMK_PKD_PRKD1_ST	Q96QB1	DLC1	Q15139	PRKD1	S735	V734I	734	Missense	proximal	-1	no	7.891	7.897	EPSD	TCGA;COSMIC	4.507	Up-regulation
CAMK_PKD_PRKD1_ST	Q96QB1	DLC1	Q15139	PRKD1	S764	A767V	767	Missense	distal	3	no	7.333	7.315	EPSD	TCGA;COSMIC	4.507	Down-regulation
CAMK_PKD_PRKD1_ST	Q96QB1	DLC1	Q15139	PRKD1	S764	T760M	760	Missense	distal	-4	no	7.333	7.334	EPSD	TCGA;COSMIC	4.507	Up-regulation
CAMK_PKD_PRKD1_ST	Q96QB1	DLC1	Q15139	PRKD1	S764	R771W	771	Missense	distal	7	no	7.333	7.332	EPSD	TCGA;GDSC;CCLE	4.507	Down-regulation
CAMK_PKD_PRKD1_ST	Q96QB1	DLC1	Q15139	PRKD1	S764	P758L	758	Missense	distal	-6	no	7.333	7.309	EPSD	TCGA;COSMIC	4.507	Down-regulation
CAMK_PKD_PRKD1_ST	Q96QB1	DLC1	Q15139	PRKD1	S764	S764R	764	Missense	central	0	yes	7.333	0.000	EPSD	TCGA;COSMIC	4.507	Loss
CAMK_PKD_PRKD1_ST	Q96QB1	DLC1	Q15139	PRKD1	S766	A767V	767	Missense	proximal	1	no	7.348	7.347	EPSD	TCGA;COSMIC	4.507	Down-regulation
CAMK_PKD_PRKD1_ST	Q96QB1	DLC1	Q15139	PRKD1	S766	T760M	760	Missense	distal	-6	no	7.348	7.354	EPSD	TCGA;COSMIC	4.507	Up-regulation
CAMK_PKD_PRKD1_ST	Q96QB1	DLC1	Q15139	PRKD1	S766	R771W	771	Missense	distal	5	no	7.348	7.229	EPSD	TCGA;GDSC;CCLE	4.507	Down-regulation
CAMK_PKD_PRKD1_ST	Q96QB1	DLC1	Q15139	PRKD1	S766	S764R	764	Missense	proximal	-2	no	7.348	9.193	EPSD	TCGA;COSMIC	4.507	Up-regulation
CAMK_PKD_PRKD1_ST	Q96QB1	DLC1	Q15139	PRKD1	S842	H848Y	848	Missense	distal	6	no	7.280	7.321	EPSD	TCGA;COSMIC	4.507	Up-regulation
CAMK_PKD_PRKD1_ST	Q96QB1	DLC1	Q15139	PRKD1	S842	P846H	846	Missense	distal	4	no	7.280	7.273	EPSD	TCGA;COSMIC	4.507	Down-regulation
CAMK_PKD_PRKD1_ST	Q96QB1	DLC1	Q15139	PRKD1	S842	N837S	837	Missense	distal	-5	no	7.280	7.120	EPSD	TCGA;COSMIC	4.507	Down-regulation
CAMK_PKD_PRKD1_ST	Q96QB1	DLC1	Q15139	PRKD1	S856	N855K	855	Missense	proximal	-1	no	8.730	8.828	EPSD	TCGA;COSMIC	4.507	Up-regulation
CAMK_PKD_PRKD1_ST	Q96QB1	DLC1	Q15139	PRKD1	S856	D858N	858	Missense	proximal	2	no	8.730	8.776	EPSD	TCGA;COSMIC	4.507	Up-regulation
CAMK_PKD_PRKD1_ST	Q96QB1	DLC1	Q15139	PRKD1	S856	K861N	861	Missense	distal	5	no	8.730	8.705	EPSD	TCGA;COSMIC	4.507	Down-regulation
CAMK_PKD_PRKD1_ST	Q96QB1	DLC1	Q15139	PRKD1	S868	R866C	866	Missense	proximal	-2	no	11.271	8.663	EPSD	TCGA;COSMIC	4.507	Down-regulation
CAMK_PKD_PRKD1_ST	Q96QB1	DLC1	Q15139	PRKD1	S868	R866P	866	Missense	proximal	-2	no	11.271	9.105	EPSD	TCGA;COSMIC	4.507	Down-regulation
CAMK_PKD_PRKD1_ST	Q96QB1	DLC1	Q15139	PRKD1	S868	K861N	861	Missense	distal	-7	no	11.271	10.924	EPSD	TCGA;COSMIC	4.507	Down-regulation
CAMK_PKD_PRKD1_ST	Q96QB1	DLC1	Q15139	PRKD1	S869	R866C	866	Missense	distal	-3	no	5.323	1.226	EPSD	TCGA;COSMIC	4.507	Loss
CAMK_PKD_PRKD1_ST	Q96QB1	DLC1	Q15139	PRKD1	S869	R866P	866	Missense	distal	-3	no	5.323	1.407	EPSD	TCGA;COSMIC	4.507	Loss
CAMK_PKD_PRKD1_ST	Q96QB1	DLC1	Q15139	PRKD1	S871	R866C	866	Missense	distal	-5	no	4.762	4.332	EPSD	TCGA;COSMIC	4.507	Loss
CAMK_PKD_PRKD1_ST	Q96QB1	DLC1	Q15139	PRKD1	S871	R866P	866	Missense	distal	-5	no	4.762	3.796	EPSD	TCGA;COSMIC	4.507	Loss
CAMK_PKD_PRKD1_ST	Q96QB1	DLC1	Q15139	PRKD1	S933	G931R	931	Missense	proximal	-2	no	1.626	4.921	EPSD	TCGA	4.507	Gain
CAMK_PKD_PRKD1_ST	Q96QB1	DLC1	Q15139	PRKD1	S986	R984S	984	Missense	proximal	-2	no	7.785	5.941	EPSD	TCGA;ICGC;COSMIC	4.507	Down-regulation
CAMK_PKD_PRKD1_ST	Q96QB1	DLC1	Q15139	PRKD1	S986	G987V	987	Missense	proximal	1	no	7.785	7.786	EPSD	TCGA;ICGC;COSMIC	4.507	Up-regulation
CAMK_PKD_PRKD1_ST	Q96QB1	DLC1	Q15139	PRKD1	S986	A990S	990	Missense	distal	4	no	7.785	7.793	EPSD	TCGA;COSMIC	4.507	Up-regulation
CAMK_PKD_PRKD1_ST	Q96QB1	DLC1	Q15139	PRKD1	S1004	H998R	998	Missense	distal	-6	no	5.932	5.945	EPSD	TCGA;ICGC;COSMIC	4.507	Up-regulation
CAMK_PKD_PRKD1_ST	Q96QB1	DLC1	Q15139	PRKD1	S1244	E1242K	1242	Missense	proximal	-2	no	8.627	9.408	PhosphoSitePlus	TCGA;ICGC;COSMIC	4.507	Up-regulation
CAMK_PKD_PRKD1_ST	Q96QB1	DLC1	Q15139	PRKD1	S1244	S1244F	1244	Missense	central	0	yes	8.627	0.000	PhosphoSitePlus	TCGA;COSMIC	4.507	Loss
CAMK_PKD_PRKD1_ST	Q96QB1	DLC1	Q15139	PRKD1	S1296	S1296Y	1296	Missense	central	0	yes	5.016	0.000	EPSD	TCGA;COSMIC	4.507	Loss
CAMK_PKD_PRKD1_ST	Q96QB1	DLC1	Q15139	PRKD1	S1296	R1294C	1294	Missense	proximal	-2	no	5.016	2.408	EPSD	TCGA;COSMIC	4.507	Loss
CAMK_PKD_PRKD1_ST	Q96QB1	DLC1	Q15139	PRKD1	S1296	N1295H	1295	Missense	proximal	-1	no	5.016	5.144	EPSD	TCGA;COSMIC	4.507	Up-regulation
CAMK_PKD_PRKD1_ST	Q96QB1	DLC1	Q15139	PRKD1	S1296	R1294H	1294	Missense	proximal	-2	no	5.016	3.070	EPSD	TCGA;COSMIC	4.507	Loss
CAMK_PKD_PRKD1_ST	Q96QB1	DLC1	Q15139	PRKD1	S1355	K1357R	1357	Missense	proximal	2	no	4.622	4.662	EPSD	TCGA;COSMIC	4.507	Up-regulation
CAMK_PKD_PRKD1_ST	Q96QB1	DLC1	Q15139	PRKD1	S1355	S1355F	1355	Missense	central	0	yes	4.622	0.000	EPSD	TCGA;COSMIC	4.507	Loss
CAMK_PKD_PRKD1_ST	Q96QB1	DLC1	Q15139	PRKD1	S1355	E1361K	1361	Missense	distal	6	no	4.622	4.623	EPSD	TCGA;COSMIC	4.507	Up-regulation
CAMK_PKD_PRKD1_ST	P16220	CREB1	Q15139	PRKD1	S98	S103A	103	Missense	distal	5	no	8.878	8.900	PhosphoSitePlus;EPSD	TCGA;COSMIC	4.507	Up-regulation
CAMK_PKD_PRKD1_ST	P16220	CREB1	Q15139	PRKD1	S133	L128I	128	Missense	distal	-5	no	11.270	9.613	EPSD;PhosphoSitePlus	TCGA;COSMIC	4.507	Down-regulation
CAMK_PKD_PRKD1_ST	O00429	DNM1L	Q15139	PRKD1	S175	R172Q	172	Missense	distal	-3	no	5.588	1.176	EPSD	TCGA;COSMIC	4.507	Loss
CAMK_PKD_PRKD1_ST	O00429	DNM1L	Q15139	PRKD1	S529	S533F	533	Missense	distal	4	no	5.617	5.641	EPSD	TCGA;ICGC;COSMIC	4.507	Up-regulation
CAMK_PKD_PRKD1_ST	O00429	DNM1L	Q15139	PRKD1	S529	S534C	534	Missense	distal	5	no	5.617	5.571	EPSD	TCGA;ICGC;COSMIC	4.507	Down-regulation
CAMK_PKD_PRKD1_ST	O00429	DNM1L	Q15139	PRKD1	S529	R522K	522	Missense	distal	-7	no	5.617	5.356	EPSD	TCGA;COSMIC	4.507	Down-regulation
CAMK_PKD_PRKD1_ST	O00429	DNM1L	Q15139	PRKD1	S637	R639Q	639	Missense	proximal	2	no	9.050	9.033	PhosphoSitePlus	TCGA;COSMIC	4.507	Down-regulation
CAMK_PKD_PRKD1_ST	O00429	DNM1L	Q15139	PRKD1	S637	K635E	635	Missense	proximal	-2	no	9.050	8.269	PhosphoSitePlus	TCGA;COSMIC	4.507	Down-regulation
CAMK_PKD_PRKD1_ST	O60602	TLR5	Q15139	PRKD1	S805	Q811K	811	Missense	distal	6	no	7.063	7.079	PhosphoSitePlus	TCGA;ICGC;COSMIC	4.507	Up-regulation
CAMK_PKD_PRKD1_ST	Q7KZI7	MARK2	Q15139	PRKD1	S29	M34V	34	Missense	distal	5	no	5.003	4.966	EPSD	TCGA;ICGC;COSMIC	4.507	Down-regulation
CAMK_PKD_PRKD1_ST	Q7KZI7	MARK2	Q15139	PRKD1	S400	N402S	402	Missense	proximal	2	no	7.781	7.865	PhosphoSitePlus	TCGA;ICGC;COSMIC	4.507	Up-regulation
CAMK_PKD_PRKD1_ST	Q7KZI7	MARK2	Q15139	PRKD1	S400	V399M	399	Missense	proximal	-1	no	7.781	7.890	PhosphoSitePlus	TCGA;ICGC;COSMIC	4.507	Up-regulation
CAMK_PKD_PRKD1_ST	Q7KZI7	MARK2	Q15139	PRKD1	S409	N402S	402	Missense	distal	-7	no	7.728	8.055	EPSD	TCGA;ICGC;COSMIC	4.507	Up-regulation
CAMK_PKD_PRKD1_ST	Q7KZI7	MARK2	Q15139	PRKD1	S493	G495S	495	Missense	proximal	2	no	7.004	7.161	EPSD	TCGA;COSMIC	4.507	Up-regulation
CAMK_PKD_PRKD1_ST	Q7KZI7	MARK2	Q15139	PRKD1	S493	P487S	487	Missense	distal	-6	no	7.004	7.014	EPSD	TCGA;COSMIC	4.507	Up-regulation
CAMK_PKD_PRKD1_ST	Q7KZI7	MARK2	Q15139	PRKD1	S493	R491W	491	Missense	proximal	-2	no	7.004	3.541	EPSD	TCGA;COSMIC	4.507	Loss
CAMK_PKD_PRKD1_ST	Q7KZI7	MARK2	Q15139	PRKD1	S514	P509L	509	Missense	distal	-5	no	4.180	7.025	EPSD	TCGA;COSMIC	4.507	Gain
CAMK_PKD_PRKD1_ST	Q7KZI7	MARK2	Q15139	PRKD1	T515	S514Y	514	Missense	proximal	-1	no	5.825	5.524	EPSD	TCGA;COSMIC	4.507	Down-regulation
CAMK_PKD_PRKD1_ST	Q7KZI7	MARK2	Q15139	PRKD1	T515	P509L	509	Missense	distal	-6	no	5.825	5.801	EPSD	TCGA;COSMIC	4.507	Down-regulation
CAMK_PKD_PRKD1_ST	Q7KZI7	MARK2	Q15139	PRKD1	T515	T515M	515	Missense	central	0	yes	5.825	0.000	EPSD	TCGA;COSMIC	4.507	Loss
CAMK_PKD_PRKD1_ST	Q7KZI7	MARK2	Q15139	PRKD1	S519	S514Y	514	Missense	distal	-5	no	5.316	4.472	EPSD	TCGA;COSMIC	4.507	Loss
CAMK_PKD_PRKD1_ST	Q7KZI7	MARK2	Q15139	PRKD1	S519	A524V	524	Missense	distal	5	no	5.316	5.234	EPSD	TCGA;COSMIC	4.507	Down-regulation
CAMK_PKD_PRKD1_ST	Q7KZI7	MARK2	Q15139	PRKD1	S519	T515M	515	Missense	distal	-4	no	5.316	5.317	EPSD	TCGA;COSMIC	4.507	Up-regulation
CAMK_PKD_PRKD1_ST	Q7KZI7	MARK2	Q15139	PRKD1	S523	R528C	528	Missense	distal	5	no	5.154	5.088	EPSD	TCGA;COSMIC	4.507	Down-regulation
CAMK_PKD_PRKD1_ST	Q7KZI7	MARK2	Q15139	PRKD1	S535	R528C	528	Missense	distal	-7	no	5.216	4.763	EPSD	TCGA;COSMIC	4.507	Down-regulation
CAMK_PKD_PRKD1_ST	Q7KZI7	MARK2	Q15139	PRKD1	S535	N541Y	541	Missense	distal	6	no	5.216	5.240	EPSD	TCGA;COSMIC	4.507	Up-regulation
CAMK_PKD_PRKD1_ST	Q7KZI7	MARK2	Q15139	PRKD1	T560	R557Q	557	Missense	distal	-3	no	5.659	1.247	EPSD	TCGA;COSMIC	4.507	Loss
CAMK_PKD_PRKD1_ST	Q7KZI7	MARK2	Q15139	PRKD1	T560	P566S	566	Missense	distal	6	no	5.659	5.639	EPSD	TCGA;COSMIC	4.507	Down-regulation
CAMK_PKD_PRKD1_ST	Q7KZI7	MARK2	Q15139	PRKD1	S592	H598N	598	Missense	distal	6	no	4.964	4.982	EPSD	TCGA	4.507	Up-regulation
CAMK_PKD_PRKD1_ST	Q7KZI7	MARK2	Q15139	PRKD1	S592	T596P	596	Missense	distal	4	no	4.964	4.959	EPSD	TCGA;COSMIC	4.507	Down-regulation
CAMK_PKD_PRKD1_ST	Q7KZI7	MARK2	Q15139	PRKD1	S592	R594Q	594	Missense	proximal	2	no	4.964	4.947	EPSD	TCGA;COSMIC	4.507	Down-regulation
CAMK_PKD_PRKD1_ST	Q7KZI7	MARK2	Q15139	PRKD1	S648	R644H	644	Missense	distal	-4	no	6.682	6.677	EPSD	TCGA;COSMIC	4.507	Down-regulation
CAMK_PKD_PRKD1_ST	Q7KZI7	MARK2	Q15139	PRKD1	S769	S769L	769	Missense	central	0	yes	7.348	0.000	EPSD	TCGA;COSMIC	4.507	Loss
CAMK_PKD_PRKD1_ST	Q7KZI7	MARK2	Q15139	PRKD1	S769	R767W	767	Missense	proximal	-2	no	7.348	3.885	EPSD	TCGA	4.507	Loss
CAMK_PKD_PRKD1_ST	Q15276	RABEP1	Q15139	PRKD1	S162	E166K	166	Missense	distal	4	no	11.521	11.520	EPSD	TCGA;ICGC;COSMIC	4.507	Down-regulation
CAMK_PKD_PRKD1_ST	Q15276	RABEP1	Q15139	PRKD1	S162	R159I	159	Missense	distal	-3	no	11.521	6.437	EPSD	TCGA;ICGC	4.507	Down-regulation
CAMK_PKD_PRKD1_ST	Q15276	RABEP1	Q15139	PRKD1	S229	R231M	231	Missense	proximal	2	no	6.146	6.094	EPSD	TCGA;ICGC	4.507	Down-regulation
CAMK_PKD_PRKD1_ST	Q15276	RABEP1	Q15139	PRKD1	S357	Q354E	354	Missense	distal	-3	no	4.699	4.990	EPSD	TCGA;ICGC;COSMIC	4.507	Up-regulation
CAMK_PKD_PRKD1_ST	Q15276	RABEP1	Q15139	PRKD1	S374	D379Y	379	Missense	distal	5	no	4.566	4.542	EPSD	TCGA;ICGC;COSMIC	4.507	Down-regulation
CAMK_PKD_PRKD1_ST	Q15276	RABEP1	Q15139	PRKD1	S374	S370N	370	Missense	distal	-4	no	4.566	4.558	EPSD	TCGA;ICGC	4.507	Down-regulation
CAMK_PKD_PRKD1_ST	O75628	REM1	Q15139	PRKD1	S18	R15Q	15	Missense	distal	-3	no	10.863	6.450	PhosphoSitePlus	TCGA;ICGC;COSMIC	4.507	Down-regulation
CAMK_PKD_PRKD1_ST	O75628	REM1	Q15139	PRKD1	S18	R15L	15	Missense	distal	-3	no	10.863	5.935	PhosphoSitePlus	TCGA;ICGC;COSMIC	4.507	Down-regulation
CAMK_PKD_PRKD1_ST	O75628	REM1	Q15139	PRKD1	T19	R15Q	15	Missense	distal	-4	no	6.291	6.287	EPSD	TCGA;ICGC;COSMIC	4.507	Down-regulation
CAMK_PKD_PRKD1_ST	O75628	REM1	Q15139	PRKD1	T19	R26L	26	Missense	distal	7	no	6.291	6.290	EPSD	TCGA;ICGC;COSMIC;GDSC;CCLE	4.507	Down-regulation
CAMK_PKD_PRKD1_ST	O75628	REM1	Q15139	PRKD1	T19	R15L	15	Missense	distal	-4	no	6.291	6.281	EPSD	TCGA;ICGC;COSMIC	4.507	Down-regulation
CAMK_PKD_PRKD1_ST	O75628	REM1	Q15139	PRKD1	S51	P55S	55	Missense	distal	4	no	5.252	5.245	EPSD	TCGA;ICGC;COSMIC	4.507	Down-regulation
CAMK_PKD_PRKD1_ST	O75628	REM1	Q15139	PRKD1	S51	R45W	45	Missense	distal	-6	no	5.252	5.219	EPSD	TCGA;ICGC;COSMIC	4.507	Down-regulation
CAMK_PKD_PRKD1_ST	O75628	REM1	Q15139	PRKD1	S250	R248P	248	Missense	proximal	-2	no	10.549	8.383	EPSD	TCGA;ICGC;COSMIC	4.507	Down-regulation
CAMK_PKD_PRKD1_ST	Q9NRA0	SPHK2	Q15139	PRKD1	S107	S111L	111	Missense	distal	4	no	7.062	7.067	EPSD	TCGA;COSMIC	4.507	Up-regulation
CAMK_PKD_PRKD1_ST	Q9NRA0	SPHK2	Q15139	PRKD1	S107	R106C	106	Missense	proximal	-1	no	7.062	6.870	EPSD	TCGA;COSMIC;GDSC	4.507	Down-regulation
CAMK_PKD_PRKD1_ST	Q9NRA0	SPHK2	Q15139	PRKD1	S109	S111L	111	Missense	proximal	2	no	6.868	6.790	EPSD	TCGA;COSMIC	4.507	Down-regulation
CAMK_PKD_PRKD1_ST	Q9NRA0	SPHK2	Q15139	PRKD1	S109	R106C	106	Missense	distal	-3	no	6.868	2.771	EPSD	TCGA;COSMIC;GDSC	4.507	Loss
CAMK_PKD_PRKD1_ST	Q9NRA0	SPHK2	Q15139	PRKD1	S421	L425V	425	Missense	distal	4	no	8.102	8.105	PhosphoSitePlus;EPSD	TCGA;COSMIC	4.507	Up-regulation
CAMK_PKD_PRKD1_ST	Q9NRA0	SPHK2	Q15139	PRKD1	S421	R418H	418	Missense	distal	-3	no	8.102	4.116	PhosphoSitePlus;EPSD	TCGA;COSMIC;CCLE	4.507	Loss
CAMK_PKD_PRKD1_ST	Q9NRA0	SPHK2	Q15139	PRKD1	S421	L425F	425	Missense	distal	4	no	8.102	8.121	PhosphoSitePlus;EPSD	TCGA;COSMIC	4.507	Up-regulation
CAMK_PKD_PRKD1_ST	Q9NRA0	SPHK2	Q15139	PRKD1	S487	S484P	484	Missense	distal	-3	no	5.505	6.025	EPSD	TCGA;COSMIC	4.507	Up-regulation
CAMK_PKD_PRKD1_ST	Q9NRA0	SPHK2	Q15139	PRKD1	S497	P502S	502	Missense	distal	5	no	4.461	4.507	EPSD	TCGA	4.507	Gain
CAMK_PKD_PRKD1_ST	Q99683	MAP3K5	Q15139	PRKD1	S83	R80Q	80	Missense	distal	-3	no	4.917	0.505	EPSD	TCGA	4.507	Loss
CAMK_PKD_PRKD1_ST	Q99683	MAP3K5	Q15139	PRKD1	S613	S615C	615	Missense	proximal	2	no	6.022	5.966	EPSD	TCGA;COSMIC	4.507	Down-regulation
CAMK_PKD_PRKD1_ST	Q99683	MAP3K5	Q15139	PRKD1	S613	S607C	607	Missense	distal	-6	no	6.022	6.008	EPSD	TCGA;COSMIC	4.507	Down-regulation
CAMK_PKD_PRKD1_ST	Q99683	MAP3K5	Q15139	PRKD1	S613	S613N	613	Missense	central	0	yes	6.022	0.000	EPSD	TCGA;COSMIC	4.507	Loss
CAMK_PKD_PRKD1_ST	Q99683	MAP3K5	Q15139	PRKD1	S613	V609F	609	Missense	distal	-4	no	6.022	6.021	EPSD	TCGA;ICGC;COSMIC	4.507	Down-regulation
CAMK_PKD_PRKD1_ST	Q99683	MAP3K5	Q15139	PRKD1	S719	L722P	722	Missense	distal	3	no	5.470	5.468	EPSD	TCGA;ICGC;COSMIC	4.507	Down-regulation
CAMK_PKD_PRKD1_ST	Q99683	MAP3K5	Q15139	PRKD1	S906	P901L	901	Missense	distal	-5	no	2.311	5.156	EPSD	TCGA;COSMIC	4.507	Gain
CAMK_PKD_PRKD1_ST	Q99683	MAP3K5	Q15139	PRKD1	S966	S966F	966	Missense	central	0	yes	5.837	0.000	EPSD	TCGA;COSMIC;CCLE	4.507	Loss
CAMK_PKD_PRKD1_ST	Q99683	MAP3K5	Q15139	PRKD1	S966	P968L	968	Missense	proximal	2	no	5.837	5.802	EPSD	TCGA;COSMIC	4.507	Down-regulation
CAMK_PKD_PRKD1_ST	Q99683	MAP3K5	Q15139	PRKD1	T1059	T1059M	1059	Missense	central	0	yes	6.060	0.000	EPSD	TCGA;COSMIC	4.507	Loss
CAMK_PKD_PRKD1_ST	Q99683	MAP3K5	Q15139	PRKD1	S1111	T1108I	1108	Missense	distal	-3	no	5.209	3.636	EPSD	TCGA;ICGC	4.507	Loss
CAMK_PKD_PRKD1_ST	O96013	PAK4	Q15139	PRKD1	S99	T95I	95	Missense	distal	-4	no	8.722	8.719	PhosphoSitePlus	TCGA;ICGC;COSMIC	4.507	Down-regulation
CAMK_PKD_PRKD1_ST	O96013	PAK4	Q15139	PRKD1	S104	R110H	110	Missense	distal	6	no	9.929	9.927	EPSD	TCGA;ICGC;COSMIC	4.507	Down-regulation
CAMK_PKD_PRKD1_ST	O96013	PAK4	Q15139	PRKD1	T213	P209L	209	Missense	distal	-4	no	4.657	4.654	EPSD	TCGA;ICGC	4.507	Down-regulation
CAMK_PKD_PRKD1_ST	O96013	PAK4	Q15139	PRKD1	T213	R218W	218	Missense	distal	5	no	4.657	4.538	EPSD	TCGA;ICGC;COSMIC	4.507	Down-regulation
CAMK_PKD_PRKD1_ST	O96013	PAK4	Q15139	PRKD1	S243	S246F	246	Missense	distal	3	no	4.809	4.784	EPSD	TCGA;ICGC;COSMIC	4.507	Down-regulation
CAMK_PKD_PRKD1_ST	O96013	PAK4	Q15139	PRKD1	S243	Q241H	241	Missense	proximal	-2	no	4.809	4.830	EPSD	TCGA;ICGC;COSMIC	4.507	Up-regulation
CAMK_PKD_PRKD1_ST	O96013	PAK4	Q15139	PRKD1	T251	R254Q	254	Missense	distal	3	no	5.212	5.205	EPSD	TCGA;ICGC;COSMIC	4.507	Down-regulation
CAMK_PKD_PRKD1_ST	O96013	PAK4	Q15139	PRKD1	T251	S246F	246	Missense	distal	-5	no	5.212	4.324	EPSD	TCGA;ICGC;COSMIC	4.507	Loss
CAMK_PKD_PRKD1_ST	O96013	PAK4	Q15139	PRKD1	S474	P479L	479	Missense	distal	5	no	11.240	11.228	EPSD	TCGA;ICGC;COSMIC	4.507	Down-regulation
CAMK_PKD_PRKD1_ST	O96013	PAK4	Q15139	PRKD1	S474	T478M	478	Missense	distal	4	no	11.240	11.227	EPSD	TCGA;ICGC;COSMIC	4.507	Down-regulation
CAMK_PKD_PRKD1_ST	O96013	PAK4	Q15139	PRKD1	S474	S474L	474	Missense	central	0	yes	11.240	0.000	EPSD	TCGA;ICGC;COSMIC;GDSC;CCLE	4.507	Loss
CAMK_PKD_PRKD1_ST	P27986	PIK3R1	Q15139	PRKD1	S83	P89L	89	Missense	distal	6	no	5.137	5.143	EPSD	TCGA;ICGC;COSMIC	4.507	Up-regulation
CAMK_PKD_PRKD1_ST	P27986	PIK3R1	Q15139	PRKD1	S83	Y76C	76	Missense	distal	-7	no	5.137	5.455	EPSD	TCGA;ICGC	4.507	Up-regulation
CAMK_PKD_PRKD1_ST	P27986	PIK3R1	Q15139	PRKD1	S154	S147L	147	Missense	distal	-7	no	9.099	8.574	PhosphoSitePlus	TCGA;ICGC;COSMIC	4.507	Down-regulation
CAMK_PKD_PRKD1_ST	P27986	PIK3R1	Q15139	PRKD1	S154	L149P	149	Missense	distal	-5	no	9.099	6.254	PhosphoSitePlus	TCGA	4.507	Down-regulation
CAMK_PKD_PRKD1_ST	P27986	PIK3R1	Q15139	PRKD1	S652	F646S	646	Missense	distal	-6	no	9.404	9.433	EPSD	TCGA;COSMIC	4.507	Up-regulation
CAMK_PKD_PRKD1_ST	P27986	PIK3R1	Q15139	PRKD1	S652	F646V	646	Missense	distal	-6	no	9.404	9.412	EPSD	TCGA;COSMIC	4.507	Up-regulation
CAMK_PKD_PRKD1_ST	P27986	PIK3R1	Q15139	PRKD1	S652	C659R	659	Missense	distal	7	no	9.404	9.405	EPSD	TCGA;COSMIC	4.507	Up-regulation
CAMK_PKD_PRKD1_ST	P31749	AKT1	Q15139	PRKD1	T72	T65M	65	Missense	distal	-7	no	4.787	4.806	EPSD	TCGA;ICGC;COSMIC	4.507	Up-regulation
CAMK_PKD_PRKD1_ST	P31749	AKT1	Q15139	PRKD1	T72	R69W	69	Missense	distal	-3	no	4.787	-0.586	EPSD	TCGA;ICGC;COSMIC	4.507	Loss
CAMK_PKD_PRKD1_ST	P31749	AKT1	Q15139	PRKD1	S124	R121W	121	Missense	distal	-3	no	6.544	1.171	EPSD	TCGA;ICGC;COSMIC	4.507	Loss
CAMK_PKD_PRKD1_ST	P31749	AKT1	Q15139	PRKD1	S124	A131T	131	Missense	distal	7	no	6.544	6.543	EPSD	TCGA;ICGC;COSMIC	4.507	Down-regulation
CAMK_PKD_PRKD1_ST	P31749	AKT1	Q15139	PRKD1	S422	Y417C	417	Missense	distal	-5	no	5.041	5.840	EPSD	TCGA;ICGC;COSMIC	4.507	Up-regulation
CAMK_PKD_PRKD1_ST	P31749	AKT1	Q15139	PRKD1	S422	E418K	418	Missense	distal	-4	no	5.041	5.043	EPSD	TCGA;ICGC	4.507	Up-regulation
CAMK_PKD_PRKD1_ST	Q96A00	PPP1R14A	Q15139	PRKD1	T38	R36C	36	Missense	proximal	-2	no	6.887	4.279	PhosphoSitePlus	TCGA;ICGC;COSMIC	4.507	Loss
CAMK_PKD_PRKD1_ST	Q96A00	PPP1R14A	Q15139	PRKD1	T38	R44W	44	Missense	distal	6	no	6.887	6.919	PhosphoSitePlus	TCGA;ICGC;COSMIC	4.507	Up-regulation
CAMK_PKD_PRKD1_ST	Q14896	MYBPC3	Q15139	PRKD1	S275	R282W	282	Missense	distal	7	no	9.937	9.936	EPSD	TCGA;ICGC;COSMIC	4.507	Down-regulation
CAMK_PKD_PRKD1_ST	Q14896	MYBPC3	Q15139	PRKD1	S284	D285A	285	Missense	proximal	1	no	6.808	6.809	EPSD	TCGA;ICGC;COSMIC	4.507	Up-regulation
CAMK_PKD_PRKD1_ST	Q14896	MYBPC3	Q15139	PRKD1	S284	R282W	282	Missense	proximal	-2	no	6.808	3.344	EPSD	TCGA;ICGC;COSMIC	4.507	Loss
CAMK_PKD_PRKD1_ST	Q14896	MYBPC3	Q15139	PRKD1	S284	E288D	288	Missense	distal	4	no	6.808	6.821	EPSD	TCGA;ICGC	4.507	Up-regulation
CAMK_PKD_PRKD1_ST	Q14896	MYBPC3	Q15139	PRKD1	S304	K301N	301	Missense	distal	-3	no	10.158	7.247	PhosphoSitePlus	TCGA;ICGC;COSMIC	4.507	Down-regulation
CAMK_PKD_PRKD1_ST	Q14896	MYBPC3	Q15139	PRKD1	S304	R306Q	306	Missense	proximal	2	no	10.158	10.141	PhosphoSitePlus	TCGA;ICGC;COSMIC	4.507	Down-regulation
CAMK_PKD_PRKD1_ST	Q14896	MYBPC3	Q15139	PRKD1	S304	K301R	301	Missense	distal	-3	no	10.158	12.829	PhosphoSitePlus	TCGA;ICGC;COSMIC	4.507	Up-regulation
CAMK_PKD_PRKD1_ST	Q14896	MYBPC3	Q15139	PRKD1	S304	P308L	308	Missense	distal	4	no	10.158	10.155	PhosphoSitePlus	TCGA;ICGC;COSMIC	4.507	Down-regulation
CAMK_PKD_PRKD1_ST	Q14896	MYBPC3	Q15139	PRKD1	S311	R306Q	306	Missense	distal	-5	no	4.851	4.137	EPSD	TCGA;ICGC;COSMIC	4.507	Loss
CAMK_PKD_PRKD1_ST	Q14896	MYBPC3	Q15139	PRKD1	S311	P308L	308	Missense	distal	-3	no	4.851	3.839	EPSD	TCGA;ICGC;COSMIC	4.507	Loss
CAMK_PKD_PRKD1_ST	Q14896	MYBPC3	Q15139	PRKD1	S311	E314V	314	Missense	distal	3	no	4.851	4.846	EPSD	TCGA;ICGC;COSMIC	4.507	Down-regulation
CAMK_PKD_PRKD1_ST	Q14896	MYBPC3	Q15139	PRKD1	S830	H831Y	831	Missense	proximal	1	no	5.021	5.020	EPSD	TCGA;ICGC;COSMIC	4.507	Down-regulation
CAMK_PKD_PRKD1_ST	Q14896	MYBPC3	Q15139	PRKD1	S830	R835C	835	Missense	distal	5	no	5.021	4.955	EPSD	TCGA;ICGC;COSMIC	4.507	Down-regulation
CAMK_PKD_PRKD1_ST	Q14896	MYBPC3	Q15139	PRKD1	S830	R835H	835	Missense	distal	5	no	5.021	4.985	EPSD	TCGA;ICGC;COSMIC	4.507	Down-regulation
CAMK_PKD_PRKD1_ST	O60331	PIP5K1C	Q15139	PRKD1	S448	P454A	454	Missense	distal	6	no	7.969	7.949	PhosphoSitePlus	TCGA;ICGC;COSMIC	4.507	Down-regulation
CAMK_PKD_PRKD1_ST	O60331	PIP5K1C	Q15139	PRKD1	S448	R445W	445	Missense	distal	-3	no	7.969	2.596	PhosphoSitePlus	TCGA;ICGC;COSMIC	4.507	Loss
CAMK_PKD_PRKD1_ST	O60331	PIP5K1C	Q15139	PRKD1	S455	P454A	454	Missense	proximal	-1	no	4.692	4.823	EPSD	TCGA;ICGC;COSMIC	4.507	Up-regulation
CAMK_PKD_PRKD1_ST	O60331	PIP5K1C	Q15139	PRKD1	S455	R459C	459	Missense	distal	4	no	4.692	4.703	EPSD	TCGA;ICGC;COSMIC;CCLE	4.507	Up-regulation
CAMK_PKD_PRKD1_ST	O60331	PIP5K1C	Q15139	PRKD1	S496	R492W	492	Missense	distal	-4	no	4.536	4.523	EPSD	TCGA;ICGC;COSMIC	4.507	Down-regulation
CAMK_PKD_PRKD1_ST	O60331	PIP5K1C	Q15139	PRKD1	S496	T499M	499	Missense	distal	3	no	4.536	4.546	EPSD	TCGA;ICGC;COSMIC;GDSC;CCLE	4.507	Up-regulation
CAMK_PKD_PRKD1_ST	O60331	PIP5K1C	Q15139	PRKD1	S541	S541L	541	Missense	central	0	yes	7.574	0.000	EPSD	TCGA;ICGC;COSMIC	4.507	Loss
CAMK_PKD_PRKD1_ST	O60331	PIP5K1C	Q15139	PRKD1	S541	S534F	534	Missense	distal	-7	no	7.574	7.193	EPSD	TCGA;ICGC;COSMIC	4.507	Down-regulation
CAMK_PKD_PRKD1_ST	O60331	PIP5K1C	Q15139	PRKD1	S541	R548W	548	Missense	distal	7	no	7.574	7.573	EPSD	TCGA;ICGC;COSMIC	4.507	Down-regulation
CAMK_PKD_PRKD1_ST	O60331	PIP5K1C	Q15139	PRKD1	S541	P540S	540	Missense	proximal	-1	no	7.574	7.670	EPSD	TCGA;ICGC;COSMIC	4.507	Up-regulation
CAMK_PKD_PRKD1_ST	O60331	PIP5K1C	Q15139	PRKD1	S541	R538Q	538	Missense	distal	-3	no	7.574	3.162	EPSD	TCGA;ICGC;COSMIC	4.507	Loss
CAMK_PKD_PRKD1_ST	O60331	PIP5K1C	Q15139	PRKD1	S541	R538W	538	Missense	distal	-3	no	7.574	2.201	EPSD	TCGA;ICGC	4.507	Loss
CAMK_PKD_PRKD1_ST	O60331	PIP5K1C	Q15139	PRKD1	T553	R551Q	551	Missense	proximal	-2	no	8.040	6.073	EPSD	TCGA;ICGC;COSMIC	4.507	Down-regulation
CAMK_PKD_PRKD1_ST	O60331	PIP5K1C	Q15139	PRKD1	T553	R548W	548	Missense	distal	-5	no	8.040	7.203	EPSD	TCGA;ICGC;COSMIC	4.507	Down-regulation
CAMK_PKD_PRKD1_ST	O60331	PIP5K1C	Q15139	PRKD1	T553	R548Q	548	Missense	distal	-5	no	8.040	7.326	EPSD	TCGA;ICGC	4.507	Down-regulation
CAMK_PKD_PRKD1_ST	O60331	PIP5K1C	Q15139	PRKD1	T553	R551W	551	Missense	proximal	-2	no	8.040	4.577	EPSD	TCGA;ICGC;COSMIC	4.507	Down-regulation
CAMK_PKD_PRKD1_ST	O60331	PIP5K1C	Q15139	PRKD1	S555	R551Q	551	Missense	distal	-4	no	7.198	7.193	EPSD	TCGA;ICGC;COSMIC	4.507	Down-regulation
CAMK_PKD_PRKD1_ST	O60331	PIP5K1C	Q15139	PRKD1	S555	R548W	548	Missense	distal	-7	no	7.198	6.513	EPSD	TCGA;ICGC;COSMIC	4.507	Down-regulation
CAMK_PKD_PRKD1_ST	O60331	PIP5K1C	Q15139	PRKD1	S555	R548Q	548	Missense	distal	-7	no	7.198	6.923	EPSD	TCGA;ICGC	4.507	Down-regulation
CAMK_PKD_PRKD1_ST	O60331	PIP5K1C	Q15139	PRKD1	S555	R561S	561	Missense	distal	6	no	7.198	7.186	EPSD	TCGA;ICGC;COSMIC	4.507	Down-regulation
CAMK_PKD_PRKD1_ST	O60331	PIP5K1C	Q15139	PRKD1	S555	R561T	561	Missense	distal	6	no	7.198	7.216	EPSD	TCGA;ICGC;COSMIC	4.507	Up-regulation
CAMK_PKD_PRKD1_ST	O60331	PIP5K1C	Q15139	PRKD1	S555	R551W	551	Missense	distal	-4	no	7.198	7.185	EPSD	TCGA;ICGC;COSMIC	4.507	Down-regulation
CAMK_PKD_PRKD1_ST	Q15139	PRKD1	Q15139	PRKD1	S205	R200M	200	Missense	distal	-5	no	10.262	10.515	EPSD	TCGA;ICGC;COSMIC	4.507	Up-regulation
CAMK_PKD_PRKD1_ST	Q15139	PRKD1	Q15139	PRKD1	S205	R201W	201	Missense	distal	-4	no	10.262	10.249	EPSD	TCGA;ICGC;COSMIC	4.507	Down-regulation
CAMK_PKD_PRKD1_ST	Q15139	PRKD1	Q15139	PRKD1	S219	S223C	223	Missense	distal	4	no	6.546	6.553	EPSD	TCGA;ICGC;COSMIC	4.507	Up-regulation
CAMK_PKD_PRKD1_ST	Q15139	PRKD1	Q15139	PRKD1	S219	R216C	216	Missense	distal	-3	no	6.546	2.449	EPSD	TCGA;ICGC;COSMIC	4.507	Loss
CAMK_PKD_PRKD1_ST	Q15139	PRKD1	Q15139	PRKD1	S219	S213T	213	Missense	distal	-6	no	6.546	6.529	EPSD	TCGA;ICGC;COSMIC	4.507	Down-regulation
CAMK_PKD_PRKD1_ST	Q15139	PRKD1	Q15139	PRKD1	S219	V212A	212	Missense	distal	-7	no	6.546	7.058	EPSD	TCGA;ICGC	4.507	Up-regulation
CAMK_PKD_PRKD1_ST	Q15139	PRKD1	Q15139	PRKD1	S219	V212I	212	Missense	distal	-7	no	6.546	6.610	EPSD	TCGA;ICGC;COSMIC	4.507	Up-regulation
CAMK_PKD_PRKD1_ST	Q15139	PRKD1	Q15139	PRKD1	S223	S223C	223	Missense	central	0	yes	4.978	0.000	EPSD	TCGA;ICGC;COSMIC	4.507	Loss
CAMK_PKD_PRKD1_ST	Q15139	PRKD1	Q15139	PRKD1	S223	R216C	216	Missense	distal	-7	no	4.978	4.525	EPSD	TCGA;ICGC;COSMIC	4.507	Down-regulation
CAMK_PKD_PRKD1_ST	Q15139	PRKD1	Q15139	PRKD1	S223	E229K	229	Missense	distal	6	no	4.978	4.979	EPSD	TCGA;ICGC;COSMIC	4.507	Up-regulation
CAMK_PKD_PRKD1_ST	Q15139	PRKD1	Q15139	PRKD1	S223	D228N	228	Missense	distal	5	no	4.978	5.015	EPSD	TCGA;ICGC;COSMIC	4.507	Up-regulation
CAMK_PKD_PRKD1_ST	Q15139	PRKD1	Q15139	PRKD1	S237	L231F	231	Missense	distal	-6	no	7.026	7.031	EPSD	TCGA;ICGC;COSMIC	4.507	Up-regulation
CAMK_PKD_PRKD1_ST	Q15139	PRKD1	Q15139	PRKD1	S249	N248D	248	Missense	proximal	-1	no	5.773	5.679	EPSD	TCGA;ICGC;COSMIC	4.507	Down-regulation
CAMK_PKD_PRKD1_ST	Q15139	PRKD1	Q15139	PRKD1	S249	Y252C	252	Missense	distal	3	no	5.773	5.795	EPSD	TCGA;ICGC;COSMIC	4.507	Up-regulation
CAMK_PKD_PRKD1_ST	Q15139	PRKD1	Q15139	PRKD1	S397	A392G	392	Missense	distal	-5	no	7.330	6.253	EPSD	TCGA;COSMIC	4.507	Down-regulation
CAMK_PKD_PRKD1_ST	Q15139	PRKD1	Q15139	PRKD1	S397	P398L	398	Missense	proximal	1	no	7.330	7.329	EPSD	TCGA;COSMIC	4.507	Down-regulation
CAMK_PKD_PRKD1_ST	Q15139	PRKD1	Q15139	PRKD1	S420	K414N	414	Missense	distal	-6	no	6.150	6.140	EPSD	TCGA	4.507	Down-regulation
CAMK_PKD_PRKD1_ST	Q15139	PRKD1	Q15139	PRKD1	S421	K414N	414	Missense	distal	-7	no	6.747	6.399	EPSD	TCGA	4.507	Down-regulation
CAMK_PKD_PRKD1_ST	Q15139	PRKD1	Q15139	PRKD1	S473	I471M	471	Missense	proximal	-2	no	3.545	4.644	EPSD	TCGA;COSMIC	4.507	Gain
CAMK_PKD_PRKD1_ST	Q15139	PRKD1	Q15139	PRKD1	S742	R740Q	740	Missense	proximal	-2	no	5.218	3.251	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	4.507	Loss
CAMK_PKD_PRKD1_ST	Q15139	PRKD1	Q15139	PRKD1	S742	P747T	747	Missense	distal	5	no	5.218	5.209	EPSD;PhosphoSitePlus	TCGA;COSMIC	4.507	Down-regulation
CAMK_PKD_PRKD1_ST	Q15139	PRKD1	Q15139	PRKD1	S742	T746A	746	Missense	distal	4	no	5.218	5.198	EPSD;PhosphoSitePlus	TCGA	4.507	Down-regulation
CAMK_PKD_PRKD1_ST	Q15139	PRKD1	Q15139	PRKD1	S829	V822L	822	Missense	distal	-7	no	7.429	7.324	EPSD	TCGA;COSMIC	4.507	Down-regulation
CAMK_PKD_PRKD1_ST	Q15139	PRKD1	Q15139	PRKD1	S829	R827H	827	Missense	proximal	-2	no	7.429	5.482	EPSD	TCGA;COSMIC	4.507	Down-regulation
CAMK_PKD_PRKD1_ST	Q15139	PRKD1	Q15139	PRKD1	S829	H836N	836	Missense	distal	7	no	7.429	7.428	EPSD	TCGA;COSMIC	4.507	Down-regulation
CAMK_PKD_PRKD1_ST	Q15139	PRKD1	Q15139	PRKD1	S829	H836L	836	Missense	distal	7	no	7.429	7.428	EPSD	TCGA;COSMIC	4.507	Down-regulation
CAMK_PKD_PRKD1_ST	Q15139	PRKD1	Q15139	PRKD1	S829	R827C	827	Missense	proximal	-2	no	7.429	4.821	EPSD	TCGA;COSMIC	4.507	Down-regulation
CAMK_PKD_PRKD1_ST	Q15139	PRKD1	Q15139	PRKD1	S829	K826N	826	Missense	distal	-3	no	7.429	4.518	EPSD	TCGA	4.507	Down-regulation
CAMK_PKD_PRKD1_ST	Q15139	PRKD1	Q15139	PRKD1	S890	S888R	888	Missense	proximal	-2	no	3.798	5.642	EPSD	TCGA;COSMIC	4.507	Gain
CAMK_PKD_PRKD1_ST	Q13936	CACNA1C	Q15139	PRKD1	S465	T471I	471	Missense	distal	6	no	6.235	6.236	EPSD	TCGA;ICGC;COSMIC	4.507	Up-regulation
CAMK_PKD_PRKD1_ST	Q13936	CACNA1C	Q15139	PRKD1	S465	R462Q	462	Missense	distal	-3	no	6.235	1.823	EPSD	TCGA;ICGC;COSMIC	4.507	Loss
CAMK_PKD_PRKD1_ST	Q13936	CACNA1C	Q15139	PRKD1	S863	P857L	857	Missense	distal	-6	no	7.174	7.150	EPSD	TCGA;ICGC;COSMIC	4.507	Down-regulation
CAMK_PKD_PRKD1_ST	Q13936	CACNA1C	Q15139	PRKD1	S863	L865F	865	Missense	proximal	2	no	7.174	7.106	EPSD	TCGA;ICGC;COSMIC	4.507	Down-regulation
CAMK_PKD_PRKD1_ST	Q13936	CACNA1C	Q15139	PRKD1	S863	P857T	857	Missense	distal	-6	no	7.174	7.166	EPSD	TCGA;ICGC;COSMIC	4.507	Down-regulation
CAMK_PKD_PRKD1_ST	Q13936	CACNA1C	Q15139	PRKD1	S863	R858H	858	Missense	distal	-5	no	7.174	7.051	EPSD	TCGA;ICGC;COSMIC	4.507	Down-regulation
CAMK_PKD_PRKD1_ST	Q13936	CACNA1C	Q15139	PRKD1	S863	R860Q	860	Missense	distal	-3	no	7.174	2.762	EPSD	TCGA;ICGC	4.507	Loss
CAMK_PKD_PRKD1_ST	Q13936	CACNA1C	Q15139	PRKD1	S1645	R1643W	1643	Missense	proximal	-2	no	8.255	4.792	EPSD	TCGA;COSMIC	4.507	Down-regulation
CAMK_PKD_PRKD1_ST	Q13936	CACNA1C	Q15139	PRKD1	S1692	Q1685K	1685	Missense	distal	-7	no	5.756	5.770	EPSD	TCGA;COSMIC	4.507	Up-regulation
CAMK_PKD_PRKD1_ST	Q13936	CACNA1C	Q15139	PRKD1	S1692	A1696T	1696	Missense	distal	4	no	5.756	5.777	EPSD	TCGA;COSMIC	4.507	Up-regulation
CAMK_PKD_PRKD1_ST	Q13936	CACNA1C	Q15139	PRKD1	S1718	A1723T	1723	Missense	distal	5	no	7.118	7.041	EPSD	TCGA;COSMIC	4.507	Down-regulation
CAMK_PKD_PRKD1_ST	Q13936	CACNA1C	Q15139	PRKD1	S1718	A1723D	1723	Missense	distal	5	no	7.118	6.998	EPSD	TCGA;COSMIC	4.507	Down-regulation
CAMK_PKD_PRKD1_ST	Q13936	CACNA1C	Q15139	PRKD1	S1718	R1714Q	1714	Missense	distal	-4	no	7.118	7.114	EPSD	TCGA;COSMIC	4.507	Down-regulation
CAMK_PKD_PRKD1_ST	Q13936	CACNA1C	Q15139	PRKD1	S1718	G1719E	1719	Missense	proximal	1	no	7.118	7.119	EPSD	TCGA;COSMIC	4.507	Up-regulation
CAMK_PKD_PRKD1_ST	Q13936	CACNA1C	Q15139	PRKD1	S1718	I1717V	1717	Missense	proximal	-1	no	7.118	7.112	EPSD	TCGA;COSMIC	4.507	Down-regulation
CAMK_PKD_PRKD1_ST	Q13936	CACNA1C	Q15139	PRKD1	S1718	D1720A	1720	Missense	proximal	2	no	7.118	7.289	EPSD	TCGA	4.507	Up-regulation
CAMK_PKD_PRKD1_ST	Q13936	CACNA1C	Q15139	PRKD1	S1718	P1711H	1711	Missense	distal	-7	no	7.118	7.149	EPSD	TCGA;COSMIC	4.507	Up-regulation
CAMK_PKD_PRKD1_ST	Q13936	CACNA1C	Q15139	PRKD1	S1736	A1737T	1737	Missense	proximal	1	no	5.230	5.229	EPSD	TCGA;COSMIC	4.507	Down-regulation
CAMK_PKD_PRKD1_ST	Q13936	CACNA1C	Q15139	PRKD1	S1736	D1742N	1742	Missense	distal	6	no	5.230	5.216	EPSD	TCGA;COSMIC	4.507	Down-regulation
CAMK_PKD_PRKD1_ST	Q13936	CACNA1C	Q15139	PRKD1	S1736	E1733Q	1733	Missense	distal	-3	no	5.230	4.940	EPSD	TCGA;COSMIC	4.507	Down-regulation
CAMK_PKD_PRKD1_ST	Q14247	CTTN	Q15139	PRKD1	S113	Q114P	114	Missense	proximal	1	no	8.345	8.344	EPSD	TCGA;ICGC;COSMIC	4.507	Down-regulation
CAMK_PKD_PRKD1_ST	Q14247	CTTN	Q15139	PRKD1	S113	S113L	113	Missense	central	0	yes	8.345	0.000	EPSD	TCGA;ICGC;COSMIC;GDSC;CCLE	4.507	Loss
CAMK_PKD_PRKD1_ST	Q14247	CTTN	Q15139	PRKD1	S150	E146G	146	Missense	distal	-4	no	5.979	5.973	EPSD	TCGA;ICGC;COSMIC	4.507	Down-regulation
CAMK_PKD_PRKD1_ST	Q14247	CTTN	Q15139	PRKD1	S150	S155F	155	Missense	distal	5	no	5.979	5.868	EPSD	TCGA;ICGC;COSMIC	4.507	Down-regulation
CAMK_PKD_PRKD1_ST	Q14247	CTTN	Q15139	PRKD1	S150	G143R	143	Missense	distal	-7	no	5.979	6.642	EPSD	TCGA;ICGC;COSMIC	4.507	Up-regulation
CAMK_PKD_PRKD1_ST	Q14247	CTTN	Q15139	PRKD1	S187	R189K	189	Missense	proximal	2	no	5.401	5.361	EPSD	TCGA;ICGC;COSMIC	4.507	Down-regulation
CAMK_PKD_PRKD1_ST	Q14247	CTTN	Q15139	PRKD1	S187	S192F	192	Missense	distal	5	no	5.401	5.289	EPSD	TCGA;ICGC;COSMIC	4.507	Down-regulation
CAMK_PKD_PRKD1_ST	Q14247	CTTN	Q15139	PRKD1	S187	H185L	185	Missense	proximal	-2	no	5.401	4.239	EPSD	TCGA;ICGC;COSMIC	4.507	Loss
CAMK_PKD_PRKD1_ST	Q14247	CTTN	Q15139	PRKD1	S192	R189K	189	Missense	distal	-3	no	4.857	2.185	EPSD	TCGA;ICGC;COSMIC	4.507	Loss
CAMK_PKD_PRKD1_ST	Q14247	CTTN	Q15139	PRKD1	S192	S192F	192	Missense	central	0	yes	4.857	0.000	EPSD	TCGA;ICGC;COSMIC	4.507	Loss
CAMK_PKD_PRKD1_ST	Q14247	CTTN	Q15139	PRKD1	S192	H185L	185	Missense	distal	-7	no	4.857	4.414	EPSD	TCGA;ICGC;COSMIC	4.507	Loss
CAMK_PKD_PRKD1_ST	Q14247	CTTN	Q15139	PRKD1	S224	H222R	222	Missense	proximal	-2	no	5.481	7.427	EPSD	TCGA;ICGC;COSMIC	4.507	Up-regulation
CAMK_PKD_PRKD1_ST	Q14247	CTTN	Q15139	PRKD1	S224	T219M	219	Missense	distal	-5	no	5.481	6.460	EPSD	TCGA;ICGC;COSMIC	4.507	Up-regulation
CAMK_PKD_PRKD1_ST	Q14247	CTTN	Q15139	PRKD1	S261	L256M	256	Missense	distal	-5	no	5.673	4.046	EPSD	TCGA;ICGC;COSMIC	4.507	Loss
CAMK_PKD_PRKD1_ST	Q14247	CTTN	Q15139	PRKD1	S282	A284V	284	Missense	proximal	2	no	7.855	7.724	EPSD	TCGA;COSMIC;CCLE	4.507	Down-regulation
CAMK_PKD_PRKD1_ST	P05412	JUN	Q15139	PRKD1	S73	S73L	73	Missense	central	0	yes	6.605	0.000	EPSD	TCGA;ICGC;COSMIC	4.507	Loss
CAMK_PKD_PRKD1_ST	P05412	JUN	Q15139	PRKD1	S84	G86W	86	Missense	proximal	2	no	4.633	4.654	EPSD	TCGA;ICGC;COSMIC	4.507	Up-regulation
CAMK_PKD_PRKD1_ST	Q9Y3E5	PTRH2	Q15139	PRKD1	S87	A83V	83	Missense	distal	-4	no	5.243	5.235	EPSD;PhosphoSitePlus	TCGA;COSMIC	4.507	Down-regulation
CAMK_PKD_PRKD1_ST	Q9Y3E5	PTRH2	Q15139	PRKD1	S87	A89V	89	Missense	proximal	2	no	5.243	5.112	EPSD;PhosphoSitePlus	TCGA;COSMIC	4.507	Down-regulation
CAMK_PKD_PRKD1_ST	Q9BST9	RTKN	Q15139	PRKD1	S63	R65Q	65	Missense	proximal	2	no	6.259	6.242	EPSD	TCGA	4.507	Down-regulation
CAMK_PKD_PRKD1_ST	Q9BST9	RTKN	Q15139	PRKD1	S106	D107H	107	Missense	proximal	1	no	8.272	8.273	EPSD	TCGA	4.507	Up-regulation
CAMK_PKD_PRKD1_ST	Q9BST9	RTKN	Q15139	PRKD1	S106	R104Q	104	Missense	proximal	-2	no	8.272	6.305	EPSD	TCGA;ICGC;COSMIC;GDSC	4.507	Down-regulation
CAMK_PKD_PRKD1_ST	Q9BST9	RTKN	Q15139	PRKD1	S106	R103W	103	Missense	distal	-3	no	8.272	2.899	EPSD	TCGA;ICGC;COSMIC	4.507	Loss
CAMK_PKD_PRKD1_ST	Q9BST9	RTKN	Q15139	PRKD1	S448	E452K	452	Missense	distal	4	no	6.828	6.827	EPSD	TCGA;COSMIC	4.507	Down-regulation
CAMK_PKD_PRKD1_ST	Q9BST9	RTKN	Q15139	PRKD1	T518	T518A	518	Missense	central	0	yes	4.736	0.000	EPSD	TCGA;COSMIC	4.507	Loss
CAMK_PKD_PRKD1_ST	Q9BST9	RTKN	Q15139	PRKD1	S520	T518A	518	Missense	proximal	-2	no	7.065	7.672	EPSD	TCGA;COSMIC	4.507	Up-regulation
CAMK_PKD_PRKD1_ST	Q12809	KCNH2	Q15139	PRKD1	S320	S318F	318	Missense	proximal	-2	no	5.175	3.621	EPSD	TCGA;COSMIC	4.507	Loss
CAMK_PKD_PRKD1_ST	Q12809	KCNH2	Q15139	PRKD1	S320	V325M	325	Missense	distal	5	no	5.175	5.212	EPSD	TCGA;COSMIC	4.507	Up-regulation
CAMK_PKD_PRKD1_ST	Q12809	KCNH2	Q15139	PRKD1	S320	R326C	326	Missense	distal	6	no	5.175	5.188	EPSD	TCGA;COSMIC	4.507	Up-regulation
CAMK_PKD_PRKD1_ST	Q12809	KCNH2	Q15139	PRKD1	S354	S351L	351	Missense	distal	-3	no	4.638	4.147	EPSD	TCGA;COSMIC	4.507	Loss
CAMK_PKD_PRKD1_ST	Q12809	KCNH2	Q15139	PRKD1	S354	I358M	358	Missense	distal	4	no	4.638	4.629	EPSD	TCGA;COSMIC	4.507	Down-regulation
CAMK_PKD_PRKD1_ST	Q12809	KCNH2	Q15139	PRKD1	S874	P869L	869	Missense	distal	-5	no	2.368	5.213	EPSD	TCGA;COSMIC	4.507	Gain
CAMK_PKD_PRKD1_ST	Q12809	KCNH2	Q15139	PRKD1	S890	R893K	893	Missense	distal	3	no	9.635	9.621	EPSD	TCGA;COSMIC	4.507	Down-regulation
CAMK_PKD_PRKD1_ST	Q12809	KCNH2	Q15139	PRKD1	S890	R892G	892	Missense	proximal	2	no	9.635	9.467	EPSD	TCGA;COSMIC	4.507	Down-regulation
CAMK_PKD_PRKD1_ST	Q12809	KCNH2	Q15139	PRKD1	S890	S890F	890	Missense	central	0	yes	9.635	0.000	EPSD	TCGA;COSMIC	4.507	Loss
CAMK_PKD_PRKD1_ST	Q12809	KCNH2	Q15139	PRKD1	S890	D896N	896	Missense	distal	6	no	9.635	9.621	EPSD	TCGA;COSMIC	4.507	Down-regulation
CAMK_PKD_PRKD1_ST	Q12809	KCNH2	Q15139	PRKD1	T895	R893K	893	Missense	proximal	-2	no	6.730	5.199	EPSD	TCGA;COSMIC	4.507	Down-regulation
CAMK_PKD_PRKD1_ST	Q12809	KCNH2	Q15139	PRKD1	T895	R892G	892	Missense	distal	-3	no	6.730	1.963	EPSD	TCGA;COSMIC	4.507	Loss
CAMK_PKD_PRKD1_ST	Q12809	KCNH2	Q15139	PRKD1	T895	S890F	890	Missense	distal	-5	no	6.730	5.841	EPSD	TCGA;COSMIC	4.507	Down-regulation
CAMK_PKD_PRKD1_ST	Q12809	KCNH2	Q15139	PRKD1	S1137	R1135C	1135	Missense	proximal	-2	no	9.193	6.585	EPSD	TCGA;COSMIC	4.507	Down-regulation
CAMK_PKD_PRKD1_ST	Q12809	KCNH2	Q15139	PRKD1	S1137	E1130K	1130	Missense	distal	-7	no	9.193	9.267	EPSD	TCGA;COSMIC	4.507	Up-regulation
CAMK_PKD_PRKD1_ST	Q12809	KCNH2	Q15139	PRKD1	S1155	P1149S	1149	Missense	distal	-6	no	9.463	9.473	EPSD	TCGA;COSMIC	4.507	Up-regulation
CAMK_PKD_PRKD1_ST	P53367	ARFIP1	Q15139	PRKD1	S28	R25C	25	Missense	distal	-3	no	6.217	2.120	EPSD	TCGA;ICGC;COSMIC	4.507	Loss
CAMK_PKD_PRKD1_ST	P53367	ARFIP1	Q15139	PRKD1	S28	D32N	32	Missense	distal	4	no	6.217	6.206	EPSD	TCGA;ICGC;COSMIC	4.507	Down-regulation
CAMK_PKD_PRKD1_ST	P05549	TFAP2A	Q15139	PRKD1	S119	R124C	124	Missense	distal	5	no	7.317	7.251	EPSD	TCGA;COSMIC	4.507	Down-regulation
CAMK_PKD_PRKD1_ST	P05549	TFAP2A	Q15139	PRKD1	S119	Q117L	117	Missense	proximal	-2	no	7.317	6.176	EPSD	TCGA;COSMIC	4.507	Down-regulation
CAMK_PKD_PRKD1_ST	P05549	TFAP2A	Q15139	PRKD1	S187	S191F	191	Missense	distal	4	no	6.466	6.490	EPSD	TCGA;COSMIC	4.507	Up-regulation
CAMK_PKD_PRKD1_ST	P05549	TFAP2A	Q15139	PRKD1	S187	S191C	191	Missense	distal	4	no	6.466	6.473	EPSD	TCGA;COSMIC	4.507	Up-regulation
CAMK_PKD_PRKD1_ST	P05549	TFAP2A	Q15139	PRKD1	S187	S181F	181	Missense	distal	-6	no	6.466	6.438	EPSD	TCGA;COSMIC	4.507	Down-regulation
CAMK_PKD_PRKD1_ST	P05549	TFAP2A	Q15139	PRKD1	S219	T224N	224	Missense	distal	5	no	4.733	4.728	EPSD	TCGA;COSMIC	4.507	Down-regulation
CAMK_PKD_PRKD1_ST	P05549	TFAP2A	Q15139	PRKD1	S225	T224N	224	Missense	proximal	-1	no	5.134	5.088	EPSD	TCGA;COSMIC	4.507	Down-regulation
CAMK_PKD_PRKD1_ST	P05549	TFAP2A	Q15139	PRKD1	S239	S239L	239	Missense	central	0	yes	9.468	0.000	EPSD	TCGA;COSMIC	4.507	Loss
CAMK_PKD_PRKD1_ST	P05549	TFAP2A	Q15139	PRKD1	S239	E242K	242	Missense	distal	3	no	9.468	9.467	EPSD	TCGA;COSMIC	4.507	Down-regulation
CAMK_PKD_PRKD1_ST	P05549	TFAP2A	Q15139	PRKD1	S258	R255K	255	Missense	distal	-3	no	9.564	6.892	PhosphoSitePlus;EPSD	TCGA;COSMIC	4.507	Down-regulation
CAMK_PKD_PRKD1_ST	P05549	TFAP2A	Q15139	PRKD1	S258	R254G	254	Missense	distal	-4	no	9.564	9.551	PhosphoSitePlus;EPSD	TCGA;COSMIC	4.507	Down-regulation
CAMK_PKD_PRKD1_ST	P05549	TFAP2A	Q15139	PRKD1	S326	R323P	323	Missense	distal	-3	no	9.393	5.477	EPSD;PhosphoSitePlus	TCGA;COSMIC	4.507	Down-regulation
CAMK_PKD_PRKD1_ST	P05549	TFAP2A	Q15139	PRKD1	S326	L321F	321	Missense	distal	-5	no	9.393	6.241	EPSD;PhosphoSitePlus	TCGA;COSMIC	4.507	Down-regulation
CAMK_PKD_PRKD1_ST	P05549	TFAP2A	Q15139	PRKD1	S326	D327E	327	Missense	proximal	1	no	9.393	9.394	EPSD;PhosphoSitePlus	TCGA	4.507	Up-regulation
CAMK_PKD_PRKD1_ST	P05549	TFAP2A	Q15139	PRKD1	S326	E330V	330	Missense	distal	4	no	9.393	9.394	EPSD;PhosphoSitePlus	TCGA;COSMIC	4.507	Up-regulation
CAMK_PKD_PRKD1_ST	Q13671	RIN1	Q15139	PRKD1	S291	L287I	287	Missense	distal	-4	no	10.565	10.564	EPSD	TCGA;ICGC	4.507	Down-regulation
CAMK_PKD_PRKD1_ST	Q13671	RIN1	Q15139	PRKD1	S292	L287I	287	Missense	distal	-5	no	9.735	8.078	EPSD;PhosphoSitePlus	TCGA;ICGC	4.507	Down-regulation
CAMK_PKD_PRKD1_ST	Q13671	RIN1	Q15139	PRKD1	S310	S304N	304	Missense	distal	-6	no	5.000	4.982	EPSD	TCGA;ICGC;COSMIC	4.507	Down-regulation
CAMK_PKD_PRKD1_ST	Q13671	RIN1	Q15139	PRKD1	S351	R344Q	344	Missense	distal	-7	no	9.466	9.192	PhosphoSitePlus;EPSD	TCGA;ICGC;COSMIC	4.507	Down-regulation
CAMK_PKD_PRKD1_ST	Q13671	RIN1	Q15139	PRKD1	S611	R616C	616	Missense	distal	5	no	10.313	10.247	EPSD	TCGA;ICGC;COSMIC	4.507	Down-regulation
CAMK_PKD_PRKD1_ST	P16144	ITGB4	Q15139	PRKD1	S7	S7R	7	Missense	central	0	yes	5.373	0.000	EPSD	TCGA;ICGC;COSMIC	4.507	Loss
CAMK_PKD_PRKD1_ST	P16144	ITGB4	Q15139	PRKD1	S7	R5H	5	Missense	proximal	-2	no	5.373	3.426	EPSD	TCGA;ICGC;COSMIC	4.507	Loss
CAMK_PKD_PRKD1_ST	P16144	ITGB4	Q15139	PRKD1	S368	E361K	361	Missense	distal	-7	no	6.506	6.580	EPSD	TCGA;ICGC;COSMIC	4.507	Up-regulation
CAMK_PKD_PRKD1_ST	P16144	ITGB4	Q15139	PRKD1	S368	A362D	362	Missense	distal	-6	no	6.506	6.476	EPSD	TCGA;ICGC;COSMIC	4.507	Down-regulation
CAMK_PKD_PRKD1_ST	P16144	ITGB4	Q15139	PRKD1	S368	E361D	361	Missense	distal	-7	no	6.506	6.119	EPSD	TCGA;ICGC	4.507	Down-regulation
CAMK_PKD_PRKD1_ST	P16144	ITGB4	Q15139	PRKD1	S368	S368F	368	Missense	central	0	yes	6.506	0.000	EPSD	TCGA;ICGC;COSMIC	4.507	Loss
CAMK_PKD_PRKD1_ST	P16144	ITGB4	Q15139	PRKD1	S368	R365Q	365	Missense	distal	-3	no	6.506	2.094	EPSD	TCGA;COSMIC	4.507	Loss
CAMK_PKD_PRKD1_ST	P16144	ITGB4	Q15139	PRKD1	S368	R373W	373	Missense	distal	5	no	6.506	6.387	EPSD	TCGA;ICGC;COSMIC	4.507	Down-regulation
CAMK_PKD_PRKD1_ST	P16144	ITGB4	Q15139	PRKD1	S397	S397F	397	Missense	central	0	yes	4.644	0.000	EPSD	TCGA;ICGC;COSMIC	4.507	Loss
CAMK_PKD_PRKD1_ST	P16144	ITGB4	Q15139	PRKD1	T776	H773R	773	Missense	distal	-3	no	1.361	5.347	EPSD	TCGA;ICGC;COSMIC	4.507	Gain
CAMK_PKD_PRKD1_ST	P16144	ITGB4	Q15139	PRKD1	T829	R823C	823	Missense	distal	-6	no	6.419	6.399	EPSD	TCGA;ICGC	4.507	Down-regulation
CAMK_PKD_PRKD1_ST	P16144	ITGB4	Q15139	PRKD1	T837	A841D	841	Missense	distal	4	no	4.490	4.518	EPSD	TCGA;ICGC;COSMIC	4.507	Gain
CAMK_PKD_PRKD1_ST	P16144	ITGB4	Q15139	PRKD1	S893	M889I	889	Missense	distal	-4	no	7.001	6.997	EPSD	TCGA;ICGC;COSMIC	4.507	Down-regulation
CAMK_PKD_PRKD1_ST	P16144	ITGB4	Q15139	PRKD1	S1097	Q1094H	1094	Missense	distal	-3	no	4.397	4.822	EPSD	TCGA;ICGC	4.507	Gain
CAMK_PKD_PRKD1_ST	P16144	ITGB4	Q15139	PRKD1	T1113	M1116K	1116	Missense	distal	3	no	8.578	8.574	EPSD	TCGA;ICGC;COSMIC	4.507	Down-regulation
CAMK_PKD_PRKD1_ST	P16144	ITGB4	Q15139	PRKD1	S1325	R1322G	1322	Missense	distal	-3	no	5.650	0.884	EPSD	TCGA;ICGC	4.507	Loss
CAMK_PKD_PRKD1_ST	P16144	ITGB4	Q15139	PRKD1	S1358	D1351N	1351	Missense	distal	-7	no	7.979	8.093	EPSD	TCGA;ICGC	4.507	Up-regulation
CAMK_PKD_PRKD1_ST	P16144	ITGB4	Q15139	PRKD1	S1358	R1355C	1355	Missense	distal	-3	no	7.979	3.882	EPSD	TCGA;ICGC;COSMIC	4.507	Loss
CAMK_PKD_PRKD1_ST	P16144	ITGB4	Q15139	PRKD1	S1358	G1359S	1359	Missense	proximal	1	no	7.979	7.980	EPSD	TCGA;ICGC;COSMIC	4.507	Up-regulation
CAMK_PKD_PRKD1_ST	P16144	ITGB4	Q15139	PRKD1	S1358	S1358L	1358	Missense	central	0	yes	7.979	0.000	EPSD	TCGA;ICGC;COSMIC	4.507	Loss
CAMK_PKD_PRKD1_ST	P16144	ITGB4	Q15139	PRKD1	S1358	R1362K	1362	Missense	distal	4	no	7.979	7.989	EPSD	TCGA;ICGC;COSMIC	4.507	Up-regulation
CAMK_PKD_PRKD1_ST	P16144	ITGB4	Q15139	PRKD1	S1403	P1398L	1398	Missense	distal	-5	no	2.629	5.474	EPSD	TCGA;ICGC;COSMIC	4.507	Gain
CAMK_PKD_PRKD1_ST	P16144	ITGB4	Q15139	PRKD1	T1463	Y1469H	1469	Missense	distal	6	no	7.080	7.039	EPSD	TCGA;COSMIC	4.507	Down-regulation
CAMK_PKD_PRKD1_ST	P16144	ITGB4	Q15139	PRKD1	T1463	M1461T	1461	Missense	proximal	-2	no	7.080	7.124	EPSD	TCGA;COSMIC	4.507	Up-regulation
CAMK_PKD_PRKD1_ST	P16144	ITGB4	Q15139	PRKD1	T1463	Y1469F	1469	Missense	distal	6	no	7.080	7.077	EPSD	TCGA;COSMIC	4.507	Down-regulation
CAMK_PKD_PRKD1_ST	P16144	ITGB4	Q15139	PRKD1	S1503	S1498L	1498	Missense	distal	-5	no	3.248	5.511	EPSD	TCGA;COSMIC	4.507	Gain
CAMK_PKD_PRKD1_ST	P16144	ITGB4	Q15139	PRKD1	S1511	S1517Y	1517	Missense	distal	6	no	6.409	6.460	EPSD	TCGA;COSMIC	4.507	Up-regulation
CAMK_PKD_PRKD1_ST	P16144	ITGB4	Q15139	PRKD1	S1511	D1509Y	1509	Missense	proximal	-2	no	6.409	6.381	EPSD	TCGA;COSMIC	4.507	Down-regulation
CAMK_PKD_PRKD1_ST	P16144	ITGB4	Q15139	PRKD1	S1604	R1599H	1599	Missense	distal	-5	no	7.520	7.397	EPSD	TCGA;COSMIC	4.507	Down-regulation
CAMK_PKD_PRKD1_ST	P16144	ITGB4	Q15139	PRKD1	S1604	G1609S	1609	Missense	distal	5	no	7.520	7.644	EPSD	TCGA;COSMIC	4.507	Up-regulation
CAMK_PKD_PRKD1_ST	P16144	ITGB4	Q15139	PRKD1	T1806	T1813S	1813	Missense	distal	7	no	6.907	6.908	EPSD	TCGA;COSMIC	4.507	Up-regulation
CAMK_PKD_PRKD1_ST	P16144	ITGB4	Q15139	PRKD1	T1806	T1810A	1810	Missense	distal	4	no	6.907	6.887	EPSD	TCGA;COSMIC	4.507	Down-regulation
CAMK_PKD_PRKD1_ST	P16144	ITGB4	Q15139	PRKD1	T1806	T1804A	1804	Missense	proximal	-2	no	6.907	7.515	EPSD	TCGA	4.507	Up-regulation
CAMK_PKD_PRKD1_ST	P16144	ITGB4	Q15139	PRKD1	T1810	T1813S	1813	Missense	distal	3	no	4.922	4.935	EPSD	TCGA;COSMIC	4.507	Up-regulation
CAMK_PKD_PRKD1_ST	P16144	ITGB4	Q15139	PRKD1	T1810	M1815V	1815	Missense	distal	5	no	4.922	4.885	EPSD	TCGA;COSMIC	4.507	Down-regulation
CAMK_PKD_PRKD1_ST	P16144	ITGB4	Q15139	PRKD1	T1810	T1810A	1810	Missense	central	0	yes	4.922	0.000	EPSD	TCGA;COSMIC	4.507	Loss
CAMK_PKD_PRKD1_ST	P16144	ITGB4	Q15139	PRKD1	T1810	T1804A	1804	Missense	distal	-6	no	4.922	4.943	EPSD	TCGA	4.507	Up-regulation
CAMK_PKD_PRKD1_ST	P02686	MBP	Q15139	PRKD1	S26	E25K	25	Missense	proximal	-1	no	5.290	5.334	EPSD	TCGA;ICGC;COSMIC	4.507	Up-regulation
CAMK_PKD_PRKD1_ST	P02686	MBP	Q15139	PRKD1	S26	K29N	29	Missense	distal	3	no	5.290	5.284	EPSD	TCGA;ICGC;COSMIC	4.507	Down-regulation
CAMK_PKD_PRKD1_ST	P02686	MBP	Q15139	PRKD1	S40	R37W	37	Missense	distal	-3	no	8.257	2.884	EPSD	TCGA;ICGC;COSMIC	4.507	Loss
CAMK_PKD_PRKD1_ST	P02686	MBP	Q15139	PRKD1	S96	A99V	99	Missense	distal	3	no	7.949	7.931	EPSD	TCGA;ICGC;COSMIC	4.507	Down-regulation
CAMK_PKD_PRKD1_ST	P02686	MBP	Q15139	PRKD1	S128	D132Y	132	Missense	distal	4	no	4.768	4.774	EPSD	TCGA;ICGC;COSMIC;GDSC;CCLE	4.507	Up-regulation
CAMK_PKD_PRKD1_ST	P02686	MBP	Q15139	PRKD1	S141	G145R	145	Missense	distal	4	no	6.683	6.653	EPSD	TCGA;COSMIC	4.507	Down-regulation
CAMK_PKD_PRKD1_ST	P02686	MBP	Q15139	PRKD1	S141	R139I	139	Missense	proximal	-2	no	6.683	3.379	EPSD	TCGA;COSMIC	4.507	Loss
CAMK_PKD_PRKD1_ST	P02686	MBP	Q15139	PRKD1	S146	G145R	145	Missense	proximal	-1	no	6.250	6.591	EPSD	TCGA;COSMIC	4.507	Up-regulation
CAMK_PKD_PRKD1_ST	P02686	MBP	Q15139	PRKD1	S146	R139I	139	Missense	distal	-7	no	6.250	5.613	EPSD	TCGA;COSMIC	4.507	Down-regulation
CAMK_PKD_PRKD1_ST	P02686	MBP	Q15139	PRKD1	T154	H157R	157	Missense	distal	3	no	4.763	4.771	EPSD	TCGA;COSMIC	4.507	Up-regulation
CAMK_PKD_PRKD1_ST	P23528	CFL1	Q15139	PRKD1	S23	M18L	18	Missense	distal	-5	no	3.561	5.188	EPSD	TCGA;ICGC;COSMIC	4.507	Gain
CAMK_PKD_PRKD1_ST	P23528	CFL1	Q15139	PRKD1	S24	M18L	18	Missense	distal	-6	no	7.304	7.282	EPSD	TCGA;ICGC;COSMIC	4.507	Down-regulation
CAMK_PKD_PRKD1_ST	O95863	SNAI1	Q15139	PRKD1	S11	V7A	7	Missense	distal	-4	no	10.069	10.077	PhosphoSitePlus	TCGA;ICGC;COSMIC	4.507	Up-regulation
CAMK_PKD_PRKD1_ST	O95863	SNAI1	Q15139	PRKD1	S112	P110S	110	Missense	proximal	-2	no	4.339	4.661	EPSD	TCGA;ICGC;COSMIC	4.507	Gain
CAMK_PKD_PRKD1_ST	O95863	SNAI1	Q15139	PRKD1	T177	V181I	181	Missense	distal	4	no	6.165	6.167	EPSD	TCGA;ICGC;COSMIC	4.507	Up-regulation
CAMK_PKD_PRKD1_ST	O95863	SNAI1	Q15139	PRKD1	T177	R174Q	174	Missense	distal	-3	no	6.165	1.753	EPSD	TCGA;ICGC	4.507	Loss
CAMK_PKD_PRKD1_ST	O95863	SNAI1	Q15139	PRKD1	T177	G183R	183	Missense	distal	6	no	6.165	6.125	EPSD	TCGA;ICGC;COSMIC	4.507	Down-regulation
CAMK_PKD_PRKD1_ST	O95863	SNAI1	Q15139	PRKD1	T203	P207S	207	Missense	distal	4	no	5.387	5.379	EPSD	TCGA;ICGC;COSMIC	4.507	Down-regulation
CAMK_PKD_PRKD1_ST	O95863	SNAI1	Q15139	PRKD1	T203	E205K	205	Missense	proximal	2	no	5.387	5.405	EPSD	TCGA;ICGC;COSMIC	4.507	Up-regulation
CAMK_PKD_PRKD1_ST	O95863	SNAI1	Q15139	PRKD1	T203	R200Q	200	Missense	distal	-3	no	5.387	0.975	EPSD	TCGA;ICGC;COSMIC	4.507	Loss
CAMK_PKD_PRKD1_ST	O95863	SNAI1	Q15139	PRKD1	S246	R243Q	243	Missense	distal	-3	no	6.585	2.173	EPSD	TCGA;ICGC;COSMIC	4.507	Loss
CAMK_PKD_PRKD1_ST	O95863	SNAI1	Q15139	PRKD1	S246	C241F	241	Missense	distal	-5	no	6.585	5.742	EPSD	TCGA;ICGC;COSMIC	4.507	Down-regulation
CAMK_PKD_PRKD1_ST	P22059	OSBP	Q15139	PRKD1	T174	R169W	169	Missense	distal	-5	no	4.552	3.715	EPSD	TCGA;ICGC;COSMIC	4.507	Loss
CAMK_PKD_PRKD1_ST	P22059	OSBP	Q15139	PRKD1	T174	K180N	180	Missense	distal	6	no	4.552	4.560	EPSD	TCGA;ICGC	4.507	Up-regulation
CAMK_PKD_PRKD1_ST	P22059	OSBP	Q15139	PRKD1	S215	Q208H	208	Missense	distal	-7	no	7.306	7.218	EPSD	TCGA;ICGC;COSMIC	4.507	Down-regulation
CAMK_PKD_PRKD1_ST	P22059	OSBP	Q15139	PRKD1	S215	T210A	210	Missense	distal	-5	no	7.306	7.973	EPSD	TCGA;ICGC;COSMIC	4.507	Up-regulation
CAMK_PKD_PRKD1_ST	P22059	OSBP	Q15139	PRKD1	S215	R212W	212	Missense	distal	-3	no	7.306	1.933	EPSD	TCGA;ICGC;COSMIC	4.507	Loss
CAMK_PKD_PRKD1_ST	P22059	OSBP	Q15139	PRKD1	S216	T210A	210	Missense	distal	-6	no	4.528	4.549	EPSD	TCGA;ICGC;COSMIC	4.507	Up-regulation
CAMK_PKD_PRKD1_ST	P22059	OSBP	Q15139	PRKD1	S216	R212W	212	Missense	distal	-4	no	4.528	4.515	EPSD	TCGA;ICGC;COSMIC	4.507	Down-regulation
CAMK_PKD_PRKD1_ST	P22059	OSBP	Q15139	PRKD1	S240	R237C	237	Missense	distal	-3	no	9.709	5.612	PhosphoSitePlus	TCGA	4.507	Down-regulation
CAMK_PKD_PRKD1_ST	P22059	OSBP	Q15139	PRKD1	S240	R237H	237	Missense	distal	-3	no	9.709	5.722	PhosphoSitePlus	TCGA;ICGC;COSMIC;GDSC;CCLE	4.507	Down-regulation
CAMK_PKD_PRKD1_ST	P22059	OSBP	Q15139	PRKD1	S269	A271V	271	Missense	proximal	2	no	7.581	7.450	EPSD	TCGA;ICGC;CCLE	4.507	Down-regulation
CAMK_PKD_PRKD1_ST	P22059	OSBP	Q15139	PRKD1	T377	N371H	371	Missense	distal	-6	no	4.972	4.982	EPSD	TCGA;ICGC;COSMIC	4.507	Up-regulation
CAMK_PKD_PRKD1_ST	P22059	OSBP	Q15139	PRKD1	T628	K626N	626	Missense	proximal	-2	no	7.439	5.598	EPSD	TCGA;ICGC;COSMIC	4.507	Down-regulation
CAMK_PKD_PRKD1_ST	P22059	OSBP	Q15139	PRKD1	T628	T628M	628	Missense	central	0	yes	7.439	0.000	EPSD	TCGA;ICGC;COSMIC	4.507	Loss
CAMK_PKD_PRKD1_ST	P50552	VASP	Q15139	PRKD1	S157	R154C	154	Missense	distal	-3	no	9.857	5.760	PhosphoSitePlus;EPSD	TCGA;ICGC;COSMIC	4.507	Down-regulation
CAMK_PKD_PRKD1_ST	P50552	VASP	Q15139	PRKD1	S239	E242D	242	Missense	distal	3	no	8.087	8.068	EPSD	TCGA;ICGC;COSMIC	4.507	Down-regulation
CAMK_PKD_PRKD1_ST	P50552	VASP	Q15139	PRKD1	S255	E254K	254	Missense	proximal	-1	no	4.550	4.594	EPSD	TCGA;ICGC;COSMIC	4.507	Up-regulation
CAMK_PKD_PRKD1_ST	P50552	VASP	Q15139	PRKD1	S255	G259R	259	Missense	distal	4	no	4.550	4.520	EPSD	TCGA;ICGC;COSMIC	4.507	Down-regulation
CAMK_PKD_PRKD1_ST	P50552	VASP	Q15139	PRKD1	S255	S255G	255	Missense	central	0	yes	4.550	0.000	EPSD	TCGA;ICGC	4.507	Loss
CAMK_PKD_PRKD1_ST	P50552	VASP	Q15139	PRKD1	S322	R319W	319	Missense	distal	-3	no	9.307	3.934	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	4.507	Loss
CAMK_PKD_PRKD1_ST	P50552	VASP	Q15139	PRKD1	S322	P318S	318	Missense	distal	-4	no	9.307	9.310	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	4.507	Up-regulation
CAMK_PKD_PRKD1_ST	P50552	VASP	Q15139	PRKD1	S323	P318S	318	Missense	distal	-5	no	4.067	4.649	EPSD	TCGA;ICGC;COSMIC	4.507	Gain
CAMK_PKD_PRKD1_ST	P50552	VASP	Q15139	PRKD1	S324	E330K	330	Missense	distal	6	no	5.019	5.020	EPSD	TCGA;ICGC;COSMIC	4.507	Up-regulation
CAMK_PKD_PRKD1_ST	P50552	VASP	Q15139	PRKD1	S324	R319W	319	Missense	distal	-5	no	5.019	4.181	EPSD	TCGA;ICGC;COSMIC	4.507	Loss
CAMK_PKD_PRKD1_ST	P50552	VASP	Q15139	PRKD1	S324	P318S	318	Missense	distal	-6	no	5.019	5.028	EPSD	TCGA;ICGC;COSMIC	4.507	Up-regulation
CAMK_PKD_PRKD1_ST	Q92918	MAP4K1	Q15139	PRKD1	S171	R169C	169	Missense	proximal	-2	no	12.724	10.116	PhosphoSitePlus	TCGA;ICGC;COSMIC	4.507	Down-regulation
CAMK_PKD_PRKD1_ST	Q92918	MAP4K1	Q15139	PRKD1	S171	A164D	164	Missense	distal	-7	no	12.724	12.191	PhosphoSitePlus	TCGA;ICGC;COSMIC	4.507	Down-regulation
CAMK_PKD_PRKD1_ST	Q92918	MAP4K1	Q15139	PRKD1	S171	R169H	169	Missense	proximal	-2	no	12.724	10.777	PhosphoSitePlus	TCGA;ICGC;COSMIC	4.507	Down-regulation
CAMK_PKD_PRKD1_ST	Q92918	MAP4K1	Q15139	PRKD1	S320	P315A	315	Missense	distal	-5	no	4.490	5.396	EPSD	TCGA;ICGC;COSMIC	4.507	Gain
CAMK_PKD_PRKD1_ST	Q92918	MAP4K1	Q15139	PRKD1	S325	R323H	323	Missense	proximal	-2	no	4.519	2.573	EPSD	TCGA;ICGC	4.507	Loss
CAMK_PKD_PRKD1_ST	Q92918	MAP4K1	Q15139	PRKD1	S326	R323H	323	Missense	distal	-3	no	6.803	2.817	EPSD	TCGA;ICGC	4.507	Loss
CAMK_PKD_PRKD1_ST	Q92918	MAP4K1	Q15139	PRKD1	S368	R362Q	362	Missense	distal	-6	no	7.175	7.174	EPSD	TCGA;ICGC;COSMIC	4.507	Down-regulation
CAMK_PKD_PRKD1_ST	Q92918	MAP4K1	Q15139	PRKD1	S407	E409K	409	Missense	proximal	2	no	6.713	6.731	EPSD	TCGA;ICGC;COSMIC	4.507	Up-regulation
CAMK_PKD_PRKD1_ST	Q92918	MAP4K1	Q15139	PRKD1	S407	P401S	401	Missense	distal	-6	no	6.713	6.723	EPSD	TCGA;ICGC;COSMIC	4.507	Up-regulation
CAMK_PKD_PRKD1_ST	Q92918	MAP4K1	Q15139	PRKD1	S407	P411H	411	Missense	distal	4	no	6.713	6.706	EPSD	TCGA;ICGC;COSMIC	4.507	Down-regulation
CAMK_PKD_PRKD1_ST	Q92918	MAP4K1	Q15139	PRKD1	S407	G412R	412	Missense	distal	5	no	6.713	6.857	EPSD	TCGA;ICGC;COSMIC	4.507	Up-regulation
CAMK_PKD_PRKD1_ST	Q92918	MAP4K1	Q15139	PRKD1	S430	A429T	429	Missense	proximal	-1	no	8.323	8.175	EPSD	TCGA;ICGC;COSMIC	4.507	Down-regulation
CAMK_PKD_PRKD1_ST	Q92918	MAP4K1	Q15139	PRKD1	S430	G423R	423	Missense	distal	-7	no	8.323	8.986	EPSD	TCGA;ICGC;COSMIC;CCLE	4.507	Up-regulation
CAMK_PKD_PRKD1_ST	O00206	TLR4	Q15139	PRKD1	S790	L789V	789	Missense	proximal	-1	no	8.857	8.745	PhosphoSitePlus	TCGA;COSMIC	4.507	Down-regulation
CAMK_PKD_PRKD1_ST	O00206	TLR4	Q15139	PRKD1	S790	S790R	790	Missense	central	0	yes	8.857	0.000	PhosphoSitePlus	TCGA;COSMIC	4.507	Loss
CAMK_PKD_PRKD1_ST	O00206	TLR4	Q15139	PRKD1	S790	L785R	785	Missense	distal	-5	no	8.857	6.977	PhosphoSitePlus	TCGA	4.507	Down-regulation
CAMK_PKD_PRKD1_ST	O00206	TLR4	Q15139	PRKD1	S790	S790N	790	Missense	central	0	yes	8.857	0.000	PhosphoSitePlus	TCGA;COSMIC	4.507	Loss
CAMK_PKD_PRKD1_ST	O00206	TLR4	Q15139	PRKD1	S790	Y786H	786	Missense	distal	-4	no	8.857	8.866	PhosphoSitePlus	TCGA;COSMIC	4.507	Up-regulation
CAMK_PKD_PRKD1_ST	O00206	TLR4	Q15139	PRKD1	S800	E798K	798	Missense	proximal	-2	no	3.732	4.513	EPSD	TCGA;COSMIC	4.507	Gain
CAMK_PKD_PRKD1_ST	P04792	HSPB1	Q15139	PRKD1	S15	L10H	10	Missense	distal	-5	no	7.595	5.592	EPSD	TCGA;ICGC;COSMIC	4.507	Down-regulation
CAMK_PKD_PRKD1_ST	P04792	HSPB1	Q15139	PRKD1	S78	L81I	81	Missense	distal	3	no	7.008	7.003	EPSD	TCGA;ICGC;COSMIC	4.507	Down-regulation
CAMK_PKD_PRKD1_ST	P04792	HSPB1	Q15139	PRKD1	S82	L81I	81	Missense	proximal	-1	no	10.184	10.078	PhosphoSitePlus	TCGA;ICGC;COSMIC	4.507	Down-regulation
CAMK_PKD_PRKD1_ST	P04792	HSPB1	Q15139	PRKD1	T139	F138C	138	Missense	proximal	-1	no	5.056	5.209	EPSD	TCGA;ICGC;COSMIC	4.507	Up-regulation
CAMK_PKD_PRKD1_ST	P04792	HSPB1	Q15139	PRKD1	T143	F138C	138	Missense	distal	-5	no	5.806	6.649	EPSD	TCGA;ICGC;COSMIC	4.507	Up-regulation
CAMK_PKD_PRKD1_ST	P04792	HSPB1	Q15139	PRKD1	T162	E160K	160	Missense	proximal	-2	no	4.238	5.019	EPSD	TCGA;ICGC;COSMIC	4.507	Gain
TK_PDGFR_KIT_Y	P10721	KIT	P10721	KIT	Y547	P551H	551	Missense	distal	4	no	3.906	3.468	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	1.639	Down-regulation
TK_PDGFR_KIT_Y	P10721	KIT	P10721	KIT	Y547	M552L	552	Missense	distal	5	no	3.906	3.911	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	1.639	Up-regulation
TK_PDGFR_KIT_Y	P10721	KIT	P10721	KIT	Y547	Y545H	545	Missense	proximal	-2	no	3.906	3.904	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	1.639	Down-regulation
TK_PDGFR_KIT_Y	P10721	KIT	P10721	KIT	Y553	P551H	551	Missense	proximal	-2	no	3.485	3.480	PhosphoSitePlus;EPSD	TCGA;ICGC;COSMIC	1.639	Down-regulation
TK_PDGFR_KIT_Y	P10721	KIT	P10721	KIT	Y553	K558E	558	Missense	distal	5	no	3.485	3.481	PhosphoSitePlus;EPSD	TCGA;ICGC;COSMIC	1.639	Down-regulation
TK_PDGFR_KIT_Y	P10721	KIT	P10721	KIT	Y553	M552L	552	Missense	proximal	-1	no	3.485	3.368	PhosphoSitePlus;EPSD	TCGA;ICGC;COSMIC	1.639	Down-regulation
TK_PDGFR_KIT_Y	P10721	KIT	P10721	KIT	Y553	V559A	559	Missense	distal	6	no	3.485	3.432	PhosphoSitePlus;EPSD	TCGA;ICGC;COSMIC	1.639	Down-regulation
TK_PDGFR_KIT_Y	P10721	KIT	P10721	KIT	Y553	W557R	557	Missense	distal	4	no	3.485	3.454	PhosphoSitePlus;EPSD	TCGA;ICGC;COSMIC	1.639	Down-regulation
TK_PDGFR_KIT_Y	P10721	KIT	P10721	KIT	Y553	W557C	557	Missense	distal	4	no	3.485	3.278	PhosphoSitePlus;EPSD	TCGA;COSMIC	1.639	Down-regulation
TK_PDGFR_KIT_Y	P10721	KIT	P10721	KIT	Y553	W557G	557	Missense	distal	4	no	3.485	3.667	PhosphoSitePlus;EPSD	TCGA;COSMIC	1.639	Up-regulation
TK_PDGFR_KIT_Y	P10721	KIT	P10721	KIT	Y553	V559G	559	Missense	distal	6	no	3.485	3.405	PhosphoSitePlus;EPSD	TCGA;COSMIC	1.639	Down-regulation
TK_PDGFR_KIT_Y	P10721	KIT	P10721	KIT	Y568	E562G	562	Missense	distal	-6	no	3.400	3.467	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	1.639	Up-regulation
TK_PDGFR_KIT_Y	P10721	KIT	P10721	KIT	Y568	P573Q	573	Missense	distal	5	no	3.400	3.410	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	1.639	Up-regulation
TK_PDGFR_KIT_Y	P10721	KIT	P10721	KIT	Y568	P573L	573	Missense	distal	5	no	3.400	3.421	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	1.639	Up-regulation
TK_PDGFR_KIT_Y	P10721	KIT	P10721	KIT	Y570	P573Q	573	Missense	distal	3	no	3.527	3.517	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	1.639	Down-regulation
TK_PDGFR_KIT_Y	P10721	KIT	P10721	KIT	Y570	P573L	573	Missense	distal	3	no	3.527	3.498	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	1.639	Down-regulation
TK_PDGFR_KIT_Y	P10721	KIT	P10721	KIT	Y570	L576P	576	Missense	distal	6	no	3.527	3.454	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC;CCLE	1.639	Down-regulation
TK_PDGFR_KIT_Y	P10721	KIT	P10721	KIT	Y578	P573Q	573	Missense	distal	-5	no	1.744	1.321	EPSD	TCGA;ICGC;COSMIC	1.639	Loss
TK_PDGFR_KIT_Y	P10721	KIT	P10721	KIT	Y578	P573L	573	Missense	distal	-5	no	1.744	1.561	EPSD	TCGA;ICGC;COSMIC	1.639	Loss
TK_PDGFR_KIT_Y	P10721	KIT	P10721	KIT	Y578	L576P	576	Missense	proximal	-2	no	1.744	1.749	EPSD	TCGA;ICGC;COSMIC;CCLE	1.639	Up-regulation
TK_PDGFR_KIT_Y	P10721	KIT	P10721	KIT	Y578	Y578C	578	Missense	central	0	yes	1.744	0.000	EPSD	TCGA;COSMIC	1.639	Loss
TK_PDGFR_KIT_Y	P10721	KIT	P10721	KIT	Y703	H697D	697	Missense	distal	-6	no	3.477	3.387	EPSD;PhosphoSitePlus	TCGA	1.639	Down-regulation
TK_PDGFR_KIT_Y	P10721	KIT	P10721	KIT	Y703	D696Y	696	Missense	distal	-7	no	3.477	3.478	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	1.639	Up-regulation
TK_PDGFR_KIT_Y	P10721	KIT	P10721	KIT	Y703	L706F	706	Missense	distal	3	no	3.477	3.490	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	1.639	Up-regulation
TK_PDGFR_KIT_Y	P10721	KIT	P10721	KIT	Y703	L706P	706	Missense	distal	3	no	3.477	3.506	EPSD;PhosphoSitePlus	TCGA;ICGC	1.639	Up-regulation
TK_PDGFR_KIT_Y	P10721	KIT	P10721	KIT	Y721	E720D	720	Missense	proximal	-1	no	3.319	3.382	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	1.639	Up-regulation
TK_PDGFR_KIT_Y	P10721	KIT	P10721	KIT	Y721	Y721H	721	Missense	central	0	yes	3.319	0.000	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	1.639	Loss
TK_PDGFR_KIT_Y	P10721	KIT	P10721	KIT	Y721	D716N	716	Missense	distal	-5	no	3.319	2.734	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	1.639	Down-regulation
TK_PDGFR_KIT_Y	P10721	KIT	P10721	KIT	Y823	D816V	816	Missense	distal	-7	no	4.730	4.661	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	1.639	Down-regulation
TK_PDGFR_KIT_Y	P10721	KIT	P10721	KIT	Y823	K826N	826	Missense	distal	3	no	4.730	4.758	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	1.639	Up-regulation
TK_PDGFR_KIT_Y	P10721	KIT	P10721	KIT	Y823	K818R	818	Missense	distal	-5	no	4.730	4.695	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	1.639	Down-regulation
TK_PDGFR_KIT_Y	P10721	KIT	P10721	KIT	Y823	N822K	822	Missense	proximal	-1	no	4.730	4.639	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC;GDSC;CCLE	1.639	Down-regulation
TK_PDGFR_KIT_Y	P10721	KIT	P10721	KIT	Y823	N822I	822	Missense	proximal	-1	no	4.730	4.751	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	1.639	Up-regulation
TK_PDGFR_KIT_Y	P10721	KIT	P10721	KIT	Y823	D816Y	816	Missense	distal	-7	no	4.730	4.731	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	1.639	Up-regulation
TK_PDGFR_KIT_Y	P10721	KIT	P10721	KIT	Y823	A829P	829	Missense	distal	6	no	4.730	4.643	EPSD;PhosphoSitePlus	TCGA;COSMIC	1.639	Down-regulation
TK_PDGFR_KIT_Y	P10721	KIT	P10721	KIT	Y823	D816H	816	Missense	distal	-7	no	4.730	4.748	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	1.639	Up-regulation
TK_PDGFR_KIT_Y	P10721	KIT	P10721	KIT	Y823	N822Y	822	Missense	proximal	-1	no	4.730	4.744	EPSD;PhosphoSitePlus	TCGA;COSMIC	1.639	Up-regulation
TK_PDGFR_KIT_Y	P10721	KIT	P10721	KIT	Y823	V825D	825	Missense	proximal	2	no	4.730	4.707	EPSD;PhosphoSitePlus	TCGA	1.639	Down-regulation
TK_PDGFR_KIT_Y	P10721	KIT	P10721	KIT	Y823	S821Y	821	Missense	proximal	-2	no	4.730	4.725	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	1.639	Down-regulation
TK_PDGFR_KIT_Y	P10721	KIT	P10721	KIT	Y823	K818N	818	Missense	distal	-5	no	4.730	4.431	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	1.639	Down-regulation
TK_PDGFR_KIT_Y	P10721	KIT	P10721	KIT	Y823	K818T	818	Missense	distal	-5	no	4.730	4.516	EPSD;PhosphoSitePlus	TCGA;ICGC	1.639	Down-regulation
TK_PDGFR_KIT_Y	P10721	KIT	P10721	KIT	Y936	S937P	937	Missense	proximal	1	no	3.746	3.672	EPSD;PhosphoSitePlus	TCGA	1.639	Down-regulation
TK_PDGFR_KIT_Y	Q9GZY6	LAT2	P10721	KIT	Y110	P113H	113	Missense	distal	3	no	4.234	4.220	PhosphoSitePlus;EPSD	TCGA;ICGC;COSMIC	1.639	Down-regulation
TK_PDGFR_KIT_Y	Q9GZY6	LAT2	P10721	KIT	Y118	R123Q	123	Missense	distal	5	no	3.690	3.699	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	1.639	Up-regulation
TK_PDGFR_KIT_Y	Q9GZY6	LAT2	P10721	KIT	Y118	S125L	125	Missense	distal	7	no	3.690	3.653	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	1.639	Down-regulation
TK_PDGFR_KIT_Y	Q9GZY6	LAT2	P10721	KIT	Y118	F124L	124	Missense	distal	6	no	3.690	3.696	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	1.639	Up-regulation
TK_PDGFR_KIT_Y	Q9GZY6	LAT2	P10721	KIT	Y118	R123W	123	Missense	distal	5	no	3.690	3.701	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	1.639	Up-regulation
TK_PDGFR_KIT_Y	Q9GZY6	LAT2	P10721	KIT	Y118	P113H	113	Missense	distal	-5	no	3.690	3.435	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	1.639	Down-regulation
TK_PDGFR_KIT_Y	Q9GZY6	LAT2	P10721	KIT	Y118	Y118H	118	Missense	central	0	yes	3.690	0.000	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	1.639	Loss
Other_PEK_PKR_EIF2AK2_ST	P19525	EIF2AK2	P19525	EIF2AK2	S83	T88A	88	Missense	distal	5	no	102.539	100.625	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	66.906	Down-regulation
Other_PEK_PKR_EIF2AK2_ST	P19525	EIF2AK2	P19525	EIF2AK2	S83	K79N	79	Missense	distal	-4	no	102.539	101.004	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	66.906	Down-regulation
Other_PEK_PKR_EIF2AK2_ST	P19525	EIF2AK2	P19525	EIF2AK2	S83	K77T	77	Missense	distal	-6	no	102.539	88.008	EPSD;PhosphoSitePlus	TCGA;ICGC	66.906	Down-regulation
Other_PEK_PKR_EIF2AK2_ST	P19525	EIF2AK2	P19525	EIF2AK2	T88	T88A	88	Missense	central	0	yes	116.907	0.000	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	66.906	Loss
Other_PEK_PKR_EIF2AK2_ST	P19525	EIF2AK2	P19525	EIF2AK2	T88	S92Y	92	Missense	distal	4	no	116.907	115.336	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	66.906	Down-regulation
Other_PEK_PKR_EIF2AK2_ST	P19525	EIF2AK2	P19525	EIF2AK2	T89	T88A	88	Missense	proximal	-1	no	104.941	103.589	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	66.906	Down-regulation
Other_PEK_PKR_EIF2AK2_ST	P19525	EIF2AK2	P19525	EIF2AK2	T89	S92Y	92	Missense	distal	3	no	104.941	100.089	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	66.906	Down-regulation
Other_PEK_PKR_EIF2AK2_ST	P19525	EIF2AK2	P19525	EIF2AK2	T90	T88A	88	Missense	proximal	-2	no	96.407	97.296	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	66.906	Up-regulation
Other_PEK_PKR_EIF2AK2_ST	P19525	EIF2AK2	P19525	EIF2AK2	T90	S92Y	92	Missense	proximal	2	no	96.407	96.700	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	66.906	Up-regulation
Other_PEK_PKR_EIF2AK2_ST	P19525	EIF2AK2	P19525	EIF2AK2	S242	N235I	235	Missense	distal	-7	no	110.237	109.949	PhosphoSitePlus;EPSD	TCGA;ICGC;COSMIC	66.906	Down-regulation
Other_PEK_PKR_EIF2AK2_ST	P19525	EIF2AK2	P19525	EIF2AK2	S242	P245L	245	Missense	distal	3	no	110.237	109.873	PhosphoSitePlus;EPSD	TCGA;ICGC;COSMIC	66.906	Down-regulation
Other_PEK_PKR_EIF2AK2_ST	P19525	EIF2AK2	P19525	EIF2AK2	T255	M252I	252	Missense	distal	-3	no	117.648	118.317	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	66.906	Up-regulation
Other_PEK_PKR_EIF2AK2_ST	P19525	EIF2AK2	P19525	EIF2AK2	T255	E254K	254	Missense	proximal	-1	no	117.648	116.708	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	66.906	Down-regulation
Other_PEK_PKR_EIF2AK2_ST	P19525	EIF2AK2	P19525	EIF2AK2	T258	M252I	252	Missense	distal	-6	no	106.644	101.353	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	66.906	Down-regulation
Other_PEK_PKR_EIF2AK2_ST	P19525	EIF2AK2	P19525	EIF2AK2	T258	F263S	263	Missense	distal	5	no	106.644	106.056	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	66.906	Down-regulation
Other_PEK_PKR_EIF2AK2_ST	P19525	EIF2AK2	P19525	EIF2AK2	T258	E254K	254	Missense	distal	-4	no	106.644	107.091	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	66.906	Up-regulation
Other_PEK_PKR_EIF2AK2_ST	P05198	EIF2S1	P19525	EIF2AK2	S49	M45I	45	Missense	distal	-4	no	99.991	100.503	PhosphoSitePlus;EPSD	TCGA;ICGC;COSMIC	66.906	Up-regulation
Other_PEK_PKR_EIF2AK2_ST	P05198	EIF2S1	P19525	EIF2AK2	S49	G44C	44	Missense	distal	-5	no	99.991	97.742	PhosphoSitePlus;EPSD	TCGA;ICGC;COSMIC	66.906	Down-regulation
Other_PEK_PKR_EIF2AK2_ST	P05198	EIF2S1	P19525	EIF2AK2	S52	M45I	45	Missense	distal	-7	no	109.481	109.326	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	66.906	Down-regulation
Other_PEK_PKR_EIF2AK2_ST	P05198	EIF2S1	P19525	EIF2AK2	S52	R57C	57	Missense	distal	5	no	109.481	108.399	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	66.906	Down-regulation
Other_PEK_PKR_EIF2AK2_ST	P05198	EIF2S1	P19525	EIF2AK2	T245	T239M	239	Missense	distal	-6	no	58.293	70.553	EPSD	TCGA;ICGC;COSMIC	66.906	Gain
Other_PEK_PKR_EIF2AK2_ST	P10636	MAPT	P19525	EIF2AK2	T111	E117K	117	Missense	distal	6	no	71.982	72.654	EPSD	TCGA;ICGC;COSMIC	66.906	Up-regulation
Other_PEK_PKR_EIF2AK2_ST	P10636	MAPT	P19525	EIF2AK2	T111	A118V	118	Missense	distal	7	no	71.982	74.932	EPSD	TCGA;ICGC;COSMIC	66.906	Up-regulation
Other_PEK_PKR_EIF2AK2_ST	P10636	MAPT	P19525	EIF2AK2	T123	E117K	117	Missense	distal	-6	no	83.137	80.764	EPSD	TCGA;ICGC;COSMIC	66.906	Down-regulation
Other_PEK_PKR_EIF2AK2_ST	P10636	MAPT	P19525	EIF2AK2	T123	A118V	118	Missense	distal	-5	no	83.137	85.849	EPSD	TCGA;ICGC;COSMIC	66.906	Up-regulation
Other_PEK_PKR_EIF2AK2_ST	P10636	MAPT	P19525	EIF2AK2	T466	R472Q	472	Missense	distal	6	no	68.310	68.798	EPSD	TCGA	66.906	Up-regulation
Other_PEK_PKR_EIF2AK2_ST	P10636	MAPT	P19525	EIF2AK2	T466	R472W	472	Missense	distal	6	no	68.310	61.760	EPSD	TCGA;COSMIC	66.906	Loss
Other_PEK_PKR_EIF2AK2_ST	P10636	MAPT	P19525	EIF2AK2	T466	L459R	459	Missense	distal	-7	no	68.310	67.917	EPSD	TCGA;ICGC;COSMIC	66.906	Down-regulation
Other_PEK_PKR_EIF2AK2_ST	P10636	MAPT	P19525	EIF2AK2	T466	L459F	459	Missense	distal	-7	no	68.310	67.807	EPSD	TCGA;ICGC	66.906	Down-regulation
Other_PEK_PKR_EIF2AK2_ST	P06493	CDK1	P19525	EIF2AK2	S46	R50W	50	Missense	distal	4	no	97.058	97.835	EPSD	TCGA;ICGC;COSMIC	66.906	Up-regulation
Other_PEK_PKR_EIF2AK2_ST	Q15172	PPP2R5A	P19525	EIF2AK2	S28	R30C	30	Missense	proximal	2	no	90.252	90.325	PhosphoSitePlus	TCGA;ICGC	66.906	Up-regulation
Other_PEK_PKR_EIF2AK2_ST	P04637	TP53	P19525	EIF2AK2	S99	S106R	106	Missense	distal	7	no	65.275	67.718	EPSD	TCGA;ICGC;COSMIC;GDSC;CCLE	66.906	Gain
Other_PEK_PKR_EIF2AK2_ST	P04637	TP53	P19525	EIF2AK2	S149	W146S	146	Missense	distal	-3	no	69.762	74.312	EPSD	TCGA;ICGC;COSMIC	66.906	Up-regulation
Other_PEK_PKR_EIF2AK2_ST	P04637	TP53	P19525	EIF2AK2	S149	P152L	152	Missense	distal	3	no	69.762	69.398	EPSD	TCGA;ICGC;COSMIC;GDSC;CCLE	66.906	Down-regulation
Other_PEK_PKR_EIF2AK2_ST	P04637	TP53	P19525	EIF2AK2	S149	D148N	148	Missense	proximal	-1	no	69.762	69.539	EPSD	TCGA;ICGC;COSMIC	66.906	Down-regulation
Other_PEK_PKR_EIF2AK2_ST	P04637	TP53	P19525	EIF2AK2	S149	P151H	151	Missense	proximal	2	no	69.762	70.053	EPSD	TCGA;ICGC;COSMIC;GDSC;CCLE	66.906	Up-regulation
Other_PEK_PKR_EIF2AK2_ST	P04637	TP53	P19525	EIF2AK2	S149	P151A	151	Missense	proximal	2	no	69.762	69.410	EPSD	TCGA;ICGC;COSMIC;CCLE	66.906	Down-regulation
Other_PEK_PKR_EIF2AK2_ST	P04637	TP53	P19525	EIF2AK2	S149	R156P	156	Missense	distal	7	no	69.762	66.544	EPSD	TCGA;ICGC;COSMIC;GDSC;CCLE	66.906	Loss
Other_PEK_PKR_EIF2AK2_ST	P04637	TP53	P19525	EIF2AK2	S149	V143A	143	Missense	distal	-6	no	69.762	57.331	EPSD	TCGA;ICGC;COSMIC;GDSC;CCLE	66.906	Loss
Other_PEK_PKR_EIF2AK2_ST	P04637	TP53	P19525	EIF2AK2	S149	P151S	151	Missense	proximal	2	no	69.762	69.628	EPSD	TCGA;ICGC;COSMIC;GDSC;CCLE	66.906	Down-regulation
Other_PEK_PKR_EIF2AK2_ST	P04637	TP53	P19525	EIF2AK2	S149	L145R	145	Missense	distal	-4	no	69.762	68.900	EPSD	TCGA;ICGC;COSMIC;GDSC;CCLE	66.906	Down-regulation
Other_PEK_PKR_EIF2AK2_ST	P04637	TP53	P19525	EIF2AK2	S149	T155I	155	Missense	distal	6	no	69.762	77.940	EPSD	TCGA;ICGC;COSMIC;CCLE	66.906	Up-regulation
Other_PEK_PKR_EIF2AK2_ST	P04637	TP53	P19525	EIF2AK2	S149	V143M	143	Missense	distal	-6	no	69.762	70.042	EPSD	TCGA;ICGC;COSMIC;GDSC;CCLE	66.906	Up-regulation
Other_PEK_PKR_EIF2AK2_ST	P04637	TP53	P19525	EIF2AK2	S149	T155N	155	Missense	distal	6	no	69.762	61.226	EPSD	TCGA;ICGC;COSMIC;GDSC;CCLE	66.906	Loss
Other_PEK_PKR_EIF2AK2_ST	P04637	TP53	P19525	EIF2AK2	S149	P152S	152	Missense	distal	3	no	69.762	72.077	EPSD	TCGA;ICGC;COSMIC;CCLE	66.906	Up-regulation
Other_PEK_PKR_EIF2AK2_ST	P04637	TP53	P19525	EIF2AK2	S149	R156C	156	Missense	distal	7	no	69.762	67.483	EPSD	TCGA;ICGC;COSMIC	66.906	Down-regulation
Other_PEK_PKR_EIF2AK2_ST	P04637	TP53	P19525	EIF2AK2	S149	P151T	151	Missense	proximal	2	no	69.762	69.723	EPSD	TCGA;ICGC;COSMIC	66.906	Down-regulation
Other_PEK_PKR_EIF2AK2_ST	P04637	TP53	P19525	EIF2AK2	S149	T155P	155	Missense	distal	6	no	69.762	77.628	EPSD	TCGA;ICGC;COSMIC;CCLE	66.906	Up-regulation
Other_PEK_PKR_EIF2AK2_ST	P04637	TP53	P19525	EIF2AK2	S149	V143G	143	Missense	distal	-6	no	69.762	34.883	EPSD	TCGA;ICGC;COSMIC	66.906	Loss
Other_PEK_PKR_EIF2AK2_ST	P04637	TP53	P19525	EIF2AK2	S149	P152Q	152	Missense	distal	3	no	69.762	67.129	EPSD	TCGA;ICGC;COSMIC	66.906	Down-regulation
Other_PEK_PKR_EIF2AK2_ST	P04637	TP53	P19525	EIF2AK2	S149	R156H	156	Missense	distal	7	no	69.762	69.166	EPSD	TCGA;ICGC;COSMIC	66.906	Down-regulation
Other_PEK_PKR_EIF2AK2_ST	P04637	TP53	P19525	EIF2AK2	S149	P142L	142	Missense	distal	-7	no	69.762	69.851	EPSD	TCGA;ICGC;COSMIC	66.906	Up-regulation
Other_PEK_PKR_EIF2AK2_ST	P04637	TP53	P19525	EIF2AK2	S149	L145P	145	Missense	distal	-4	no	69.762	68.305	EPSD	TCGA;ICGC;COSMIC	66.906	Down-regulation
Other_PEK_PKR_EIF2AK2_ST	P04637	TP53	P19525	EIF2AK2	S149	Q144L	144	Missense	distal	-5	no	69.762	68.181	EPSD	TCGA;ICGC;COSMIC	66.906	Down-regulation
Other_PEK_PKR_EIF2AK2_ST	P04637	TP53	P19525	EIF2AK2	S149	Q144H	144	Missense	distal	-5	no	69.762	69.167	EPSD	TCGA;ICGC;COSMIC	66.906	Down-regulation
Other_PEK_PKR_EIF2AK2_ST	P04637	TP53	P19525	EIF2AK2	S149	G154V	154	Missense	distal	5	no	69.762	69.033	EPSD	TCGA;ICGC;COSMIC;GDSC;CCLE	66.906	Down-regulation
Other_PEK_PKR_EIF2AK2_ST	P04637	TP53	P19525	EIF2AK2	S149	P151R	151	Missense	proximal	2	no	69.762	69.854	EPSD	TCGA;ICGC;COSMIC	66.906	Up-regulation
Other_PEK_PKR_EIF2AK2_ST	P04637	TP53	P19525	EIF2AK2	S149	Q144P	144	Missense	distal	-5	no	69.762	68.541	EPSD	TCGA;ICGC;COSMIC	66.906	Down-regulation
Other_PEK_PKR_EIF2AK2_ST	P04637	TP53	P19525	EIF2AK2	S149	V143E	143	Missense	distal	-6	no	69.762	74.686	EPSD	TCGA;ICGC;COSMIC	66.906	Up-regulation
Other_PEK_PKR_EIF2AK2_ST	P04637	TP53	P19525	EIF2AK2	S149	R156G	156	Missense	distal	7	no	69.762	74.035	EPSD	TCGA;ICGC;COSMIC	66.906	Up-regulation
Other_PEK_PKR_EIF2AK2_ST	P04637	TP53	P19525	EIF2AK2	S149	P151L	151	Missense	proximal	2	no	69.762	69.435	EPSD	TCGA;ICGC;COSMIC	66.906	Down-regulation
TK_Eph_EPHA2_Y	P29317	EPHA2	P29317	EPHA2	Y575	R568H	568	Missense	distal	-7	no	3.036	2.980	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	1.229	Down-regulation
TK_Eph_EPHA2_Y	P29317	EPHA2	P29317	EPHA2	Y575	L582M	582	Missense	distal	7	no	3.036	3.004	EPSD;PhosphoSitePlus	TCGA;ICGC	1.229	Down-regulation
TK_Eph_EPHA2_Y	P29317	EPHA2	P29317	EPHA2	Y588	V589M	589	Missense	proximal	1	no	2.253	2.167	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	1.229	Down-regulation
TK_Eph_EPHA2_Y	P29317	EPHA2	P29317	EPHA2	Y588	L582M	582	Missense	distal	-6	no	2.253	2.264	EPSD;PhosphoSitePlus	TCGA;ICGC	1.229	Up-regulation
TK_Eph_EPHA2_Y	P29317	EPHA2	P29317	EPHA2	Y594	V589M	589	Missense	distal	-5	no	3.437	3.480	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	1.229	Up-regulation
TK_Eph_EPHA2_Y	P29317	EPHA2	P29317	EPHA2	Y628	G625R	625	Missense	distal	-3	no	2.273	2.362	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	1.229	Up-regulation
TK_Eph_EPHA2_Y	P29317	EPHA2	P29317	EPHA2	Y694	M689I	689	Missense	distal	-5	no	2.212	2.177	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	1.229	Down-regulation
TK_Eph_EPHA2_Y	P29317	EPHA2	P29317	EPHA2	Y694	P687L	687	Missense	distal	-7	no	2.212	2.156	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	1.229	Down-regulation
TK_Eph_EPHA2_Y	P29317	EPHA2	P29317	EPHA2	Y735	Y735C	735	Missense	central	0	yes	3.040	0.000	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	1.229	Loss
TK_Eph_EPHA2_Y	P29317	EPHA2	P29317	EPHA2	Y735	M733I	733	Missense	proximal	-2	no	3.040	3.006	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	1.229	Down-regulation
TK_Eph_EPHA2_Y	P29317	EPHA2	P29317	EPHA2	Y735	R738S	738	Missense	distal	3	no	3.040	2.987	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	1.229	Down-regulation
TK_Eph_EPHA2_Y	P29317	EPHA2	P29317	EPHA2	Y735	V736L	736	Missense	proximal	1	no	3.040	2.938	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	1.229	Down-regulation
TK_Eph_EPHA2_Y	P29317	EPHA2	P29317	EPHA2	Y772	P768L	768	Missense	distal	-4	no	2.847	2.842	PhosphoSitePlus;EPSD	TCGA;ICGC;COSMIC	1.229	Down-regulation
TK_Eph_EPHA2_Y	P29317	EPHA2	P29317	EPHA2	Y772	E769K	769	Missense	distal	-3	no	2.847	2.955	PhosphoSitePlus;EPSD	TCGA;ICGC	1.229	Up-regulation
TK_Eph_EPHA2_Y	P29317	EPHA2	P29317	EPHA2	Y921	E923K	923	Missense	proximal	2	no	2.307	2.306	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	1.229	Down-regulation
TK_Eph_EPHA2_Y	O14493	CLDN4	P29317	EPHA2	Y208	R201H	201	Missense	distal	-7	no	1.975	1.919	PhosphoSitePlus	TCGA;ICGC;COSMIC	1.229	Down-regulation
CAMK_CAMKL_LKB_STK11_ST	P60484	PTEN	Q15831	STK11	T321	L325F	325	Missense	distal	4	no	21.450	21.253	EPSD	TCGA;ICGC;COSMIC	16.403	Down-regulation
CAMK_CAMKL_LKB_STK11_ST	P60484	PTEN	Q15831	STK11	T321	L325R	325	Missense	distal	4	no	21.450	21.085	EPSD	TCGA;ICGC;COSMIC	16.403	Down-regulation
CAMK_CAMKL_LKB_STK11_ST	P60484	PTEN	Q15831	STK11	T321	K322E	322	Missense	proximal	1	no	21.450	21.417	EPSD	TCGA;ICGC;COSMIC	16.403	Down-regulation
CAMK_CAMKL_LKB_STK11_ST	P60484	PTEN	Q15831	STK11	T321	D326H	326	Missense	distal	5	no	21.450	20.174	EPSD	TCGA;ICGC;COSMIC	16.403	Down-regulation
CAMK_CAMKL_LKB_STK11_ST	P60484	PTEN	Q15831	STK11	T321	D326G	326	Missense	distal	5	no	21.450	19.937	EPSD	TCGA;ICGC;COSMIC	16.403	Down-regulation
CAMK_CAMKL_LKB_STK11_ST	P60484	PTEN	Q15831	STK11	T321	L320S	320	Missense	proximal	-1	no	21.450	21.061	EPSD	TCGA;ICGC;COSMIC	16.403	Down-regulation
CAMK_CAMKL_LKB_STK11_ST	P60484	PTEN	Q15831	STK11	T350	F347L	347	Missense	distal	-3	no	16.875	17.059	EPSD	TCGA;ICGC;COSMIC	16.403	Up-regulation
CAMK_CAMKL_LKB_STK11_ST	P60484	PTEN	Q15831	STK11	T350	Y346D	346	Missense	distal	-4	no	16.875	17.224	EPSD	TCGA;ICGC;COSMIC	16.403	Up-regulation
CAMK_CAMKL_LKB_STK11_ST	P60484	PTEN	Q15831	STK11	T350	Y346H	346	Missense	distal	-4	no	16.875	16.975	EPSD	TCGA;ICGC;COSMIC	16.403	Up-regulation
CAMK_CAMKL_LKB_STK11_ST	P60484	PTEN	Q15831	STK11	S380	E373K	373	Missense	distal	-7	no	24.486	25.192	PhosphoSitePlus;EPSD	TCGA;ICGC	16.403	Up-regulation
CAMK_CAMKL_LKB_STK11_ST	P60484	PTEN	Q15831	STK11	T398	E394K	394	Missense	distal	-4	no	16.887	16.962	EPSD	TCGA;ICGC;COSMIC	16.403	Up-regulation
CAMK_CAMKL_LKB_STK11_ST	Q7RTN6	STRADA	Q15831	STK11	S52	E48Q	48	Missense	distal	-4	no	22.120	21.697	EPSD	TCGA;COSMIC	16.403	Down-regulation
CAMK_CAMKL_LKB_STK11_ST	Q7RTN6	STRADA	Q15831	STK11	S52	A45V	45	Missense	distal	-7	no	22.120	22.303	EPSD	TCGA;ICGC;COSMIC	16.403	Up-regulation
CAMK_CAMKL_LKB_STK11_ST	Q7RTN6	STRADA	Q15831	STK11	T329	P332L	332	Missense	distal	3	no	35.152	25.706	PhosphoSitePlus;EPSD	TCGA;COSMIC	16.403	Down-regulation
CAMK_CAMKL_LKB_STK11_ST	Q7RTN6	STRADA	Q15831	STK11	T329	G322C	322	Missense	distal	-7	no	35.152	35.787	PhosphoSitePlus;EPSD	TCGA;COSMIC	16.403	Up-regulation
CAMK_CAMKL_LKB_STK11_ST	Q7RTN6	STRADA	Q15831	STK11	T329	R333Q	333	Missense	distal	4	no	35.152	35.201	PhosphoSitePlus;EPSD	TCGA	16.403	Up-regulation
CAMK_CAMKL_LKB_STK11_ST	Q7RTN6	STRADA	Q15831	STK11	T329	S324I	324	Missense	distal	-5	no	35.152	36.674	PhosphoSitePlus;EPSD	TCGA	16.403	Up-regulation
CAMK_CAMKL_LKB_STK11_ST	Q7RTN6	STRADA	Q15831	STK11	T419	E425Q	425	Missense	distal	6	no	30.557	28.005	EPSD;PhosphoSitePlus	TCGA	16.403	Down-regulation
CAMK_CAMKL_LKB_STK11_ST	Q13485	SMAD4	Q15831	STK11	T77	L78F	78	Missense	proximal	1	no	32.038	32.048	PhosphoSitePlus	TCGA;ICGC;COSMIC	16.403	Up-regulation
CAMK_CAMKL_LKB_STK11_ST	Q13485	SMAD4	Q15831	STK11	T77	K70T	70	Missense	distal	-7	no	32.038	32.549	PhosphoSitePlus	TCGA;ICGC;COSMIC	16.403	Up-regulation
CAMK_CAMKL_LKB_STK11_ST	Q13485	SMAD4	Q15831	STK11	S171	E167Q	167	Missense	distal	-4	no	23.775	23.352	EPSD	TCGA;ICGC;COSMIC	16.403	Down-regulation
CAMK_CAMKL_LKB_STK11_ST	Q13485	SMAD4	Q15831	STK11	S171	S171L	171	Missense	central	0	yes	23.775	0.000	EPSD	TCGA;ICGC;COSMIC	16.403	Loss
CAMK_CAMKL_LKB_STK11_ST	Q13485	SMAD4	Q15831	STK11	S171	H164R	164	Missense	distal	-7	no	23.775	23.198	EPSD	TCGA;ICGC;COSMIC	16.403	Down-regulation
CAMK_CAMKL_LKB_STK11_ST	P27448	MARK3	Q15831	STK11	T204	T211M	211	Missense	distal	7	no	26.250	25.540	EPSD	TCGA;ICGC	16.403	Down-regulation
CAMK_CAMKL_LKB_STK11_ST	P27448	MARK3	Q15831	STK11	T211	Y218C	218	Missense	distal	7	no	61.854	61.935	EPSD;PhosphoSitePlus	TCGA;COSMIC	16.403	Up-regulation
CAMK_CAMKL_LKB_STK11_ST	P27448	MARK3	Q15831	STK11	T211	S215C	215	Missense	distal	4	no	61.854	62.237	EPSD;PhosphoSitePlus	TCGA	16.403	Up-regulation
CAMK_CAMKL_LKB_STK11_ST	P27448	MARK3	Q15831	STK11	T211	T211M	211	Missense	central	0	yes	61.854	0.000	EPSD;PhosphoSitePlus	TCGA;ICGC	16.403	Loss
CAMK_CAMKL_LKB_STK11_ST	P27448	MARK3	Q15831	STK11	S215	Y218C	218	Missense	distal	3	no	22.083	18.590	PhosphoSitePlus;EPSD	TCGA;COSMIC	16.403	Down-regulation
CAMK_CAMKL_LKB_STK11_ST	P27448	MARK3	Q15831	STK11	S215	S215C	215	Missense	central	0	yes	22.083	0.000	PhosphoSitePlus;EPSD	TCGA	16.403	Loss
CAMK_CAMKL_LKB_STK11_ST	P27448	MARK3	Q15831	STK11	S215	P221L	221	Missense	distal	6	no	22.083	20.365	PhosphoSitePlus;EPSD	TCGA;ICGC;COSMIC	16.403	Down-regulation
CAMK_CAMKL_LKB_STK11_ST	P27448	MARK3	Q15831	STK11	S215	T211M	211	Missense	distal	-4	no	22.083	21.837	PhosphoSitePlus;EPSD	TCGA;ICGC	16.403	Down-regulation
CAMK_CAMKL_LKB_STK11_ST	P27448	MARK3	Q15831	STK11	T278	N282S	282	Missense	distal	4	no	16.513	15.709	EPSD	TCGA;ICGC;COSMIC	16.403	Loss
CAMK_CAMKL_LKB_STK11_ST	P27448	MARK3	Q15831	STK11	T278	T278A	278	Missense	central	0	yes	16.513	0.000	EPSD	TCGA;ICGC;COSMIC	16.403	Loss
CAMK_CAMKL_LKB_STK11_ST	P27448	MARK3	Q15831	STK11	T278	P273L	273	Missense	distal	-5	no	16.513	13.971	EPSD	TCGA;ICGC;COSMIC	16.403	Loss
CAMK_CAMKL_LKB_STK11_ST	P27448	MARK3	Q15831	STK11	T278	P273S	273	Missense	distal	-5	no	16.513	15.031	EPSD	TCGA;ICGC;COSMIC	16.403	Loss
CAMK_CAMKL_LKB_STK11_ST	P27448	MARK3	Q15831	STK11	T574	A575T	575	Missense	proximal	1	no	19.679	19.697	EPSD	TCGA;ICGC;COSMIC	16.403	Up-regulation
CAMK_CAMKL_LKB_STK11_ST	P27448	MARK3	Q15831	STK11	T574	P569L	569	Missense	distal	-5	no	19.679	17.137	EPSD	TCGA;ICGC;COSMIC	16.403	Down-regulation
CAMK_CAMKL_LKB_STK11_ST	P27448	MARK3	Q15831	STK11	T574	R570Q	570	Missense	distal	-4	no	19.679	19.809	EPSD	TCGA;ICGC;COSMIC	16.403	Up-regulation
CAMK_CAMKL_LKB_STK11_ST	P27448	MARK3	Q15831	STK11	T574	P580H	580	Missense	distal	6	no	19.679	18.781	EPSD	TCGA;ICGC	16.403	Down-regulation
CAMK_CAMKL_LKB_STK11_ST	P27448	MARK3	Q15831	STK11	S663	M670L	670	Missense	distal	7	no	20.973	20.169	EPSD	TCGA;COSMIC	16.403	Down-regulation
CAMK_CAMKL_LKB_STK11_ST	Q9H093	NUAK2	Q15831	STK11	T208	H201Q	201	Missense	distal	-7	no	57.217	56.907	PhosphoSitePlus	TCGA;ICGC	16.403	Down-regulation
CAMK_CAMKL_LKB_STK11_ST	Q9H093	NUAK2	Q15831	STK11	T208	Q202E	202	Missense	distal	-6	no	57.217	57.162	PhosphoSitePlus	TCGA;ICGC	16.403	Down-regulation
CAMK_CAMKL_LKB_STK11_ST	Q9H093	NUAK2	Q15831	STK11	T208	S212T	212	Missense	distal	4	no	57.217	57.828	PhosphoSitePlus	TCGA	16.403	Up-regulation
CAMK_CAMKL_LKB_STK11_ST	Q9H093	NUAK2	Q15831	STK11	T208	T208K	208	Missense	central	0	yes	57.217	0.000	PhosphoSitePlus	TCGA;ICGC	16.403	Loss
CAMK_CAMKL_LKB_STK11_ST	Q9H093	NUAK2	Q15831	STK11	T519	D525N	525	Missense	distal	6	no	24.260	22.266	EPSD	TCGA;ICGC	16.403	Down-regulation
CAMK_CAMKL_LKB_STK11_ST	Q8TDC3	BRSK1	Q15831	STK11	T189	E188K	188	Missense	proximal	-1	no	58.183	58.129	EPSD;PhosphoSitePlus	TCGA;COSMIC	16.403	Down-regulation
CAMK_CAMKL_LKB_STK11_ST	Q8TDC3	BRSK1	Q15831	STK11	T189	G192A	192	Missense	distal	3	no	58.183	50.977	EPSD;PhosphoSitePlus	TCGA;COSMIC	16.403	Down-regulation
CAMK_CAMKL_LKB_STK11_ST	Q8TDC3	BRSK1	Q15831	STK11	S669	R662C	662	Missense	distal	-7	no	16.191	17.063	EPSD	TCGA;COSMIC	16.403	Gain
CAMK_CAMKL_LKB_STK11_ST	Q8TDC3	BRSK1	Q15831	STK11	S669	R662H	662	Missense	distal	-7	no	16.191	16.768	EPSD	TCGA;COSMIC	16.403	Gain
CAMK_CAMKL_LKB_STK11_ST	Q15831	STK11	Q15831	STK11	T71	S69L	69	Missense	proximal	-2	no	15.629	19.459	EPSD	TCGA;ICGC;COSMIC	16.403	Gain
CAMK_CAMKL_LKB_STK11_ST	Q15831	STK11	Q15831	STK11	T185	P179R	179	Missense	distal	-6	no	34.196	34.261	EPSD;PhosphoSitePlus	TCGA;COSMIC	16.403	Up-regulation
CAMK_CAMKL_LKB_STK11_ST	Q15831	STK11	Q15831	STK11	T185	P179Q	179	Missense	distal	-6	no	34.196	34.263	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	16.403	Up-regulation
CAMK_CAMKL_LKB_STK11_ST	Q15831	STK11	Q15831	STK11	T189	D194N	194	Missense	distal	5	no	36.410	34.955	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC;CCLE	16.403	Down-regulation
CAMK_CAMKL_LKB_STK11_ST	Q15831	STK11	Q15831	STK11	T189	D194Y	194	Missense	distal	5	no	36.410	34.588	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC;GDSC;CCLE	16.403	Down-regulation
CAMK_CAMKL_LKB_STK11_ST	Q15831	STK11	Q15831	STK11	T189	D194H	194	Missense	distal	5	no	36.410	35.135	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC;CCLE	16.403	Down-regulation
CAMK_CAMKL_LKB_STK11_ST	Q15831	STK11	Q15831	STK11	T189	S193F	193	Missense	distal	4	no	36.410	36.430	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	16.403	Up-regulation
CAMK_CAMKL_LKB_STK11_ST	Q15831	STK11	Q15831	STK11	T189	G196V	196	Missense	distal	7	no	36.410	35.764	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	16.403	Down-regulation
CAMK_CAMKL_LKB_STK11_ST	Q15831	STK11	Q15831	STK11	T189	L195M	195	Missense	distal	6	no	36.410	37.124	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	16.403	Up-regulation
CAMK_CAMKL_LKB_STK11_ST	Q15831	STK11	Q15831	STK11	T336	R333S	333	Missense	distal	-3	no	31.420	31.549	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	16.403	Up-regulation
CAMK_CAMKL_LKB_STK11_ST	Q15831	STK11	Q15831	STK11	T363	D358N	358	Missense	distal	-5	no	33.775	32.616	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	16.403	Down-regulation
CAMK_CAMKL_LKB_STK11_ST	Q15831	STK11	Q15831	STK11	T363	D359Y	359	Missense	distal	-4	no	33.775	33.426	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	16.403	Down-regulation
CAMK_CAMKL_LKB_STK11_ST	Q15831	STK11	Q15831	STK11	T363	P369S	369	Missense	distal	6	no	33.775	32.255	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	16.403	Down-regulation
CAMK_CAMKL_LKB_STK11_ST	P57059	SIK1	Q15831	STK11	T182	S176L	176	Missense	distal	-6	no	55.113	55.136	PhosphoSitePlus	TCGA;ICGC;COSMIC	16.403	Up-regulation
CAMK_CAMKL_LKB_STK11_ST	P57059	SIK1	Q15831	STK11	T182	K175R	175	Missense	distal	-7	no	55.113	53.855	PhosphoSitePlus	TCGA;ICGC;COSMIC	16.403	Down-regulation
CAMK_CAMKL_LKB_STK11_ST	P57059	SIK1	Q15831	STK11	T182	T182M	182	Missense	central	0	yes	55.113	0.000	PhosphoSitePlus	TCGA;ICGC;COSMIC	16.403	Loss
CAMK_CAMKL_LKB_STK11_ST	P57059	SIK1	Q15831	STK11	S186	T182M	182	Missense	distal	-4	no	19.794	19.547	EPSD	TCGA;ICGC;COSMIC	16.403	Down-regulation
CAMK_CAMKL_LKB_STK11_ST	P57059	SIK1	Q15831	STK11	S186	A190T	190	Missense	distal	4	no	19.794	19.411	EPSD	TCGA;ICGC;COSMIC	16.403	Down-regulation
CAMK_CAMKL_LKB_STK11_ST	P57059	SIK1	Q15831	STK11	S545	G544W	544	Missense	proximal	-1	no	17.198	17.233	EPSD	TCGA;ICGC;COSMIC	16.403	Up-regulation
CAMK_CAMKL_LKB_STK11_ST	P57059	SIK1	Q15831	STK11	S545	A548T	548	Missense	distal	3	no	17.198	22.576	EPSD	TCGA;ICGC;COSMIC	16.403	Up-regulation
CAMK_CAMKL_LKB_STK11_ST	O14744	PRMT5	Q15831	STK11	T144	S148F	148	Missense	distal	4	no	17.893	17.912	PhosphoSitePlus	TCGA;COSMIC	16.403	Up-regulation
CAMK_CAMKL_LKB_STK11_ST	O60285	NUAK1	Q15831	STK11	T211	F208C	208	Missense	distal	-3	no	57.079	57.113	PhosphoSitePlus	TCGA;ICGC;COSMIC	16.403	Up-regulation
CAMK_CAMKL_LKB_STK11_ST	O60285	NUAK1	Q15831	STK11	T211	P216S	216	Missense	distal	5	no	57.079	56.617	PhosphoSitePlus	TCGA;ICGC;COSMIC	16.403	Down-regulation
CAMK_CAMKL_LKB_STK11_ST	O60285	NUAK1	Q15831	STK11	T211	T211M	211	Missense	central	0	yes	57.079	0.000	PhosphoSitePlus	TCGA;ICGC;COSMIC	16.403	Loss
CAMK_CAMKL_LKB_STK11_ST	O60285	NUAK1	Q15831	STK11	T211	K207R	207	Missense	distal	-4	no	57.079	56.452	PhosphoSitePlus	TCGA;ICGC;COSMIC	16.403	Down-regulation
CAMK_CAMKL_LKB_STK11_ST	O60285	NUAK1	Q15831	STK11	T211	K207T	207	Missense	distal	-4	no	57.079	57.040	PhosphoSitePlus	TCGA;ICGC;COSMIC	16.403	Down-regulation
CAMK_CAMKL_LKB_STK11_ST	O60285	NUAK1	Q15831	STK11	S267	R263Q	263	Missense	distal	-4	no	20.927	21.057	EPSD	TCGA;ICGC;COSMIC	16.403	Up-regulation
CAMK_CAMKL_LKB_STK11_ST	O60285	NUAK1	Q15831	STK11	S267	R263W	263	Missense	distal	-4	no	20.927	20.983	EPSD	TCGA	16.403	Up-regulation
CAMK_CAMKL_LKB_STK11_ST	O60285	NUAK1	Q15831	STK11	S267	S266R	266	Missense	proximal	-1	no	20.927	21.231	EPSD	TCGA;ICGC;COSMIC	16.403	Up-regulation
CAMK_CAMKL_LKB_STK11_ST	O60285	NUAK1	Q15831	STK11	S267	S266N	266	Missense	proximal	-1	no	20.927	20.761	EPSD	TCGA;ICGC;COSMIC	16.403	Down-regulation
CAMK_CAMKL_LKB_STK11_ST	O60285	NUAK1	Q15831	STK11	S542	A539S	539	Missense	distal	-3	no	24.505	24.608	EPSD	TCGA;ICGC;COSMIC	16.403	Up-regulation
CAMK_CAMKL_LKB_STK11_ST	O60285	NUAK1	Q15831	STK11	S542	M545I	545	Missense	distal	3	no	24.505	31.476	EPSD	TCGA;ICGC;COSMIC	16.403	Up-regulation
CAMK_CAMKL_LKB_STK11_ST	O60285	NUAK1	Q15831	STK11	S542	V541A	541	Missense	proximal	-1	no	24.505	24.692	EPSD	TCGA;ICGC;COSMIC	16.403	Up-regulation
CAMK_CAMKL_LKB_STK11_ST	O60285	NUAK1	Q15831	STK11	T547	S550F	550	Missense	distal	3	no	18.532	24.232	EPSD	TCGA;ICGC;COSMIC	16.403	Up-regulation
CAMK_CAMKL_LKB_STK11_ST	O60285	NUAK1	Q15831	STK11	T547	M545I	545	Missense	proximal	-2	no	18.532	16.395	EPSD	TCGA;ICGC;COSMIC	16.403	Loss
CAMK_CAMKL_LKB_STK11_ST	O60285	NUAK1	Q15831	STK11	T547	V541A	541	Missense	distal	-6	no	18.532	18.545	EPSD	TCGA;ICGC;COSMIC	16.403	Up-regulation
CAMK_CAMKL_LKB_STK11_ST	O60285	NUAK1	Q15831	STK11	S550	S550F	550	Missense	central	0	yes	17.108	0.000	EPSD	TCGA;ICGC;COSMIC	16.403	Loss
CAMK_CAMKL_LKB_STK11_ST	O60285	NUAK1	Q15831	STK11	S550	G555A	555	Missense	distal	5	no	17.108	16.884	EPSD	TCGA;ICGC;COSMIC	16.403	Down-regulation
CAMK_CAMKL_LKB_STK11_ST	O60285	NUAK1	Q15831	STK11	S550	G555D	555	Missense	distal	5	no	17.108	18.621	EPSD	TCGA;ICGC;COSMIC	16.403	Up-regulation
CAMK_CAMKL_LKB_STK11_ST	O60285	NUAK1	Q15831	STK11	S550	M545I	545	Missense	distal	-5	no	17.108	18.880	EPSD	TCGA;ICGC;COSMIC	16.403	Up-regulation
CAMK_CAMKL_LKB_STK11_ST	Q13153	PAK1	Q15831	STK11	T20	M23T	23	Missense	distal	3	no	11.061	18.506	EPSD	TCGA;ICGC;COSMIC	16.403	Gain
CAMK_CAMKL_LKB_STK11_ST	Q13153	PAK1	Q15831	STK11	T22	G27D	27	Missense	distal	5	no	18.264	19.778	EPSD	TCGA;ICGC;COSMIC	16.403	Up-regulation
CAMK_CAMKL_LKB_STK11_ST	Q13153	PAK1	Q15831	STK11	T22	M23T	23	Missense	proximal	1	no	18.264	18.284	EPSD	TCGA;ICGC;COSMIC	16.403	Up-regulation
CAMK_CAMKL_LKB_STK11_ST	Q13153	PAK1	Q15831	STK11	T22	A26V	26	Missense	distal	4	no	18.264	17.879	EPSD	TCGA;ICGC;COSMIC	16.403	Down-regulation
CAMK_CAMKL_LKB_STK11_ST	Q13153	PAK1	Q15831	STK11	T22	S28N	28	Missense	distal	6	no	18.264	19.200	EPSD	TCGA;ICGC;COSMIC	16.403	Up-regulation
CAMK_CAMKL_LKB_STK11_ST	Q13153	PAK1	Q15831	STK11	T84	H86Y	86	Missense	proximal	2	no	21.646	23.635	EPSD	TCGA;ICGC;COSMIC	16.403	Up-regulation
CAMK_CAMKL_LKB_STK11_ST	Q13153	PAK1	Q15831	STK11	T84	V87A	87	Missense	distal	3	no	21.646	20.864	EPSD	TCGA;ICGC;COSMIC	16.403	Down-regulation
CAMK_CAMKL_LKB_STK11_ST	Q13153	PAK1	Q15831	STK11	T109	L107F	107	Missense	proximal	-2	no	32.353	25.801	PhosphoSitePlus	TCGA;ICGC;COSMIC	16.403	Down-regulation
CAMK_CAMKL_LKB_STK11_ST	Q13153	PAK1	Q15831	STK11	T109	R105H	105	Missense	distal	-4	no	32.353	32.737	PhosphoSitePlus	TCGA;ICGC;COSMIC	16.403	Up-regulation
CAMK_CAMKL_LKB_STK11_ST	Q13153	PAK1	Q15831	STK11	T229	N227S	227	Missense	proximal	-2	no	16.065	18.746	EPSD	TCGA;ICGC;COSMIC	16.403	Gain
CAMK_CAMKL_LKB_STK11_ST	Q13153	PAK1	Q15831	STK11	T236	T229A	229	Missense	distal	-7	no	19.750	18.820	EPSD	TCGA;ICGC;COSMIC	16.403	Down-regulation
CAMK_CAMKL_LKB_STK11_ST	Q13153	PAK1	Q15831	STK11	T236	T230I	230	Missense	distal	-6	no	19.750	19.775	EPSD	TCGA;ICGC;COSMIC	16.403	Up-regulation
CAMK_CAMKL_LKB_STK11_ST	Q13153	PAK1	Q15831	STK11	S422	E417Q	417	Missense	distal	-5	no	30.133	28.862	EPSD	TCGA;ICGC;COSMIC	16.403	Down-regulation
CAMK_CAMKL_LKB_STK11_ST	Q13153	PAK1	Q15831	STK11	S422	R421L	421	Missense	proximal	-1	no	30.133	30.218	EPSD	TCGA;ICGC;COSMIC	16.403	Up-regulation
CAMK_CAMKL_LKB_STK11_ST	Q14680	MELK	Q15831	STK11	T361	K365T	365	Missense	distal	4	no	26.450	26.418	EPSD	TCGA;COSMIC	16.403	Down-regulation
CAMK_CAMKL_LKB_STK11_ST	Q14680	MELK	Q15831	STK11	S431	T428A	428	Missense	distal	-3	no	22.659	22.305	EPSD	TCGA;COSMIC	16.403	Down-regulation
CAMK_CAMKL_LKB_STK11_ST	Q14680	MELK	Q15831	STK11	S431	E424D	424	Missense	distal	-7	no	22.659	23.437	EPSD	TCGA;COSMIC	16.403	Up-regulation
CAMK_CAMKL_LKB_STK11_ST	Q14680	MELK	Q15831	STK11	T446	P444L	444	Missense	proximal	-2	no	14.908	19.296	EPSD	TCGA;COSMIC	16.403	Gain
CAMK_CAMKL_LKB_STK11_ST	Q14680	MELK	Q15831	STK11	T459	R463C	463	Missense	distal	4	no	18.552	19.084	EPSD	TCGA;COSMIC	16.403	Up-regulation
CAMK_CAMKL_LKB_STK11_ST	Q14680	MELK	Q15831	STK11	T494	R501M	501	Missense	distal	7	no	27.177	27.202	EPSD	TCGA	16.403	Up-regulation
CAMK_CAMKL_LKB_STK11_ST	Q96L34	MARK4	Q15831	STK11	S210	C216F	216	Missense	distal	6	no	17.604	15.192	EPSD	TCGA;ICGC;COSMIC	16.403	Loss
CAMK_CAMKL_LKB_STK11_ST	Q96L34	MARK4	Q15831	STK11	S210	S210L	210	Missense	central	0	yes	17.604	0.000	EPSD	TCGA;ICGC;COSMIC	16.403	Loss
CAMK_CAMKL_LKB_STK11_ST	Q96L34	MARK4	Q15831	STK11	S210	F206L	206	Missense	distal	-4	no	17.604	17.152	EPSD	TCGA;ICGC	16.403	Down-regulation
CAMK_CAMKL_LKB_STK11_ST	Q96L34	MARK4	Q15831	STK11	T214	C216F	216	Missense	proximal	2	no	60.238	51.792	PhosphoSitePlus	TCGA;ICGC;COSMIC	16.403	Down-regulation
CAMK_CAMKL_LKB_STK11_ST	Q96L34	MARK4	Q15831	STK11	T214	S210L	210	Missense	distal	-4	no	60.238	60.089	PhosphoSitePlus	TCGA;ICGC;COSMIC	16.403	Down-regulation
CAMK_CAMKL_LKB_STK11_ST	Q96L34	MARK4	Q15831	STK11	S458	R451Q	451	Missense	distal	-7	no	18.884	19.151	EPSD	TCGA;ICGC;COSMIC	16.403	Up-regulation
CAMK_CAMKL_LKB_STK11_ST	Q96L34	MARK4	Q15831	STK11	S458	P453S	453	Missense	distal	-5	no	18.884	17.401	EPSD	TCGA;ICGC;COSMIC	16.403	Down-regulation
CAMK_CAMKL_LKB_STK11_ST	Q96L34	MARK4	Q15831	STK11	S458	G463W	463	Missense	distal	5	no	18.884	18.216	EPSD	TCGA;ICGC;COSMIC	16.403	Down-regulation
CAMK_CAMKL_LKB_STK11_ST	Q96L34	MARK4	Q15831	STK11	T497	T495M	495	Missense	proximal	-2	no	20.753	22.110	EPSD	TCGA;ICGC	16.403	Up-regulation
CAMK_CAMKL_LKB_STK11_ST	Q96L34	MARK4	Q15831	STK11	T568	R566H	566	Missense	proximal	-2	no	24.452	22.875	EPSD	TCGA;ICGC;COSMIC;CCLE	16.403	Down-regulation
CAMK_CAMKL_LKB_STK11_ST	Q96L34	MARK4	Q15831	STK11	T568	R566C	566	Missense	proximal	-2	no	24.452	24.079	EPSD	TCGA;ICGC;COSMIC;CCLE	16.403	Down-regulation
CAMK_CAMKL_LKB_STK11_ST	P38936	CDKN1A	Q15831	STK11	T80	R86W	86	Missense	distal	6	no	18.169	17.115	PhosphoSitePlus	TCGA;ICGC;COSMIC	16.403	Down-regulation
CAMK_CAMKL_LKB_STK11_ST	P38936	CDKN1A	Q15831	STK11	T80	D87N	87	Missense	distal	7	no	18.169	17.805	PhosphoSitePlus	TCGA;ICGC;COSMIC	16.403	Down-regulation
CAMK_CAMKL_LKB_STK11_ST	P38936	CDKN1A	Q15831	STK11	T80	P79S	79	Missense	proximal	-1	no	18.169	18.678	PhosphoSitePlus	TCGA;ICGC;COSMIC	16.403	Up-regulation
CAMK_CAMKL_LKB_STK11_ST	P38936	CDKN1A	Q15831	STK11	S114	H110P	110	Missense	distal	-4	no	20.210	20.436	EPSD	TCGA;ICGC	16.403	Up-regulation
CAMK_CAMKL_LKB_STK11_ST	Q9Y2K2	SIK3	Q15831	STK11	T30	A35D	35	Missense	distal	5	no	24.342	26.079	EPSD	TCGA	16.403	Up-regulation
CAMK_CAMKL_LKB_STK11_ST	Q9Y2K2	SIK3	Q15831	STK11	T411	G413C	413	Missense	proximal	2	no	14.084	22.320	EPSD	TCGA;ICGC	16.403	Gain
CAMK_CAMKL_LKB_STK11_ST	Q8IWQ3	BRSK2	Q15831	STK11	T443	P440Q	440	Missense	distal	-3	no	34.309	34.342	EPSD	TCGA;ICGC;COSMIC	16.403	Up-regulation
CAMK_CAMKL_LKB_STK11_ST	Q8IWQ3	BRSK2	Q15831	STK11	T447	P440Q	440	Missense	distal	-7	no	28.417	28.281	EPSD	TCGA;ICGC;COSMIC	16.403	Down-regulation
CAMK_CAMKL_LKB_STK11_ST	Q9P0L2	MARK1	Q15831	STK11	T208	E206K	206	Missense	proximal	-2	no	20.448	23.032	EPSD	TCGA;COSMIC	16.403	Up-regulation
CAMK_CAMKL_LKB_STK11_ST	Q9P0L2	MARK1	Q15831	STK11	T208	N211K	211	Missense	distal	3	no	20.448	18.272	EPSD	TCGA;COSMIC	16.403	Down-regulation
CAMK_CAMKL_LKB_STK11_ST	Q9P0L2	MARK1	Q15831	STK11	T208	N205S	205	Missense	distal	-3	no	20.448	20.494	EPSD	TCGA;COSMIC	16.403	Up-regulation
CAMK_CAMKL_LKB_STK11_ST	Q9P0L2	MARK1	Q15831	STK11	T215	N211K	211	Missense	distal	-4	no	61.517	61.508	PhosphoSitePlus	TCGA;COSMIC	16.403	Down-regulation
CAMK_CAMKL_LKB_STK11_ST	Q9P0L2	MARK1	Q15831	STK11	S219	A223V	223	Missense	distal	4	no	22.096	21.711	EPSD	TCGA;COSMIC	16.403	Down-regulation
CAMK_CAMKL_LKB_STK11_ST	Q9P0L2	MARK1	Q15831	STK11	T282	K289N	289	Missense	distal	7	no	19.417	19.760	EPSD	TCGA;COSMIC;GDSC;CCLE	16.403	Up-regulation
CAMK_CAMKL_LKB_STK11_ST	Q9P0L2	MARK1	Q15831	STK11	T282	L288M	288	Missense	distal	6	no	19.417	20.132	EPSD	TCGA;COSMIC	16.403	Up-regulation
CAMK_CAMKL_LKB_STK11_ST	Q9P0L2	MARK1	Q15831	STK11	T282	D283E	283	Missense	proximal	1	no	19.417	19.375	EPSD	TCGA;COSMIC	16.403	Down-regulation
CAMK_CAMKL_LKB_STK11_ST	Q9P0L2	MARK1	Q15831	STK11	T282	D283N	283	Missense	proximal	1	no	19.417	19.404	EPSD	TCGA;COSMIC	16.403	Down-regulation
CAMK_CAMKL_LKB_STK11_ST	Q9P0L2	MARK1	Q15831	STK11	S486	I488V	488	Missense	proximal	2	no	19.278	23.296	EPSD	TCGA;COSMIC	16.403	Up-regulation
CAMK_CAMKL_LKB_STK11_ST	Q9P0L2	MARK1	Q15831	STK11	S486	N492D	492	Missense	distal	6	no	19.278	21.272	EPSD	TCGA;COSMIC	16.403	Up-regulation
CAMK_CAMKL_LKB_STK11_ST	Q9P0L2	MARK1	Q15831	STK11	T598	R603C	603	Missense	distal	5	no	16.239	16.488	EPSD	TCGA;COSMIC	16.403	Gain
CAMK_CAMKL_LKB_STK11_ST	Q9P0L2	MARK1	Q15831	STK11	T613	R606Q	606	Missense	distal	-7	no	21.439	21.706	EPSD	TCGA;COSMIC	16.403	Up-regulation
CAMK_CAMKL_LKB_STK11_ST	Q9P0L2	MARK1	Q15831	STK11	T613	H615Y	615	Missense	proximal	2	no	21.439	23.428	EPSD	TCGA;COSMIC	16.403	Up-regulation
CAMK_CAMKL_LKB_STK11_ST	Q9P0L2	MARK1	Q15831	STK11	T613	R611Q	611	Missense	proximal	-2	no	21.439	20.284	EPSD	TCGA;COSMIC	16.403	Down-regulation
CAMK_CAMKL_LKB_STK11_ST	Q9P0L2	MARK1	Q15831	STK11	T648	T648M	648	Missense	central	0	yes	18.208	0.000	EPSD	TCGA;COSMIC	16.403	Loss
CAMK_CAMKL_LKB_STK11_ST	Q9P0L2	MARK1	Q15831	STK11	S705	R701L	701	Missense	distal	-4	no	21.281	21.251	EPSD	TCGA	16.403	Down-regulation
CAMK_CAMKL_LKB_STK11_ST	Q9P0L2	MARK1	Q15831	STK11	S705	S705G	705	Missense	central	0	yes	21.281	0.000	EPSD	TCGA;COSMIC	16.403	Loss
CAMK_CAMKL_LKB_STK11_ST	Q9P0L2	MARK1	Q15831	STK11	S705	S699Y	699	Missense	distal	-6	no	21.281	21.291	EPSD	TCGA;COSMIC	16.403	Up-regulation
CAMK_CAMKL_LKB_STK11_ST	Q9P0L2	MARK1	Q15831	STK11	S705	R701W	701	Missense	distal	-4	no	21.281	21.337	EPSD	TCGA;COSMIC;CCLE	16.403	Up-regulation
CAMK_CAMKL_LKB_STK11_ST	Q9P0L2	MARK1	Q15831	STK11	S705	S710G	710	Missense	distal	5	no	21.281	21.188	EPSD	TCGA;COSMIC	16.403	Down-regulation
CAMK_CAMKL_LKB_STK11_ST	Q9P0L2	MARK1	Q15831	STK11	S705	S699C	699	Missense	distal	-6	no	21.281	21.256	EPSD	TCGA;COSMIC	16.403	Down-regulation
CAMK_CAMKL_LKB_STK11_ST	Q9P0L2	MARK1	Q15831	STK11	S705	T703A	703	Missense	proximal	-2	no	21.281	19.707	EPSD	TCGA;COSMIC	16.403	Down-regulation
CAMK_CAMKL_LKB_STK11_ST	P04637	TP53	Q15831	STK11	T155	A159V	159	Missense	distal	4	no	17.567	17.181	EPSD	TCGA;ICGC;COSMIC;GDSC;CCLE	16.403	Down-regulation
CAMK_CAMKL_LKB_STK11_ST	P04637	TP53	Q15831	STK11	T155	A161T	161	Missense	distal	6	no	17.567	17.871	EPSD	TCGA;ICGC;COSMIC;GDSC;CCLE	16.403	Up-regulation
CAMK_CAMKL_LKB_STK11_ST	P04637	TP53	Q15831	STK11	T155	P152L	152	Missense	distal	-3	no	17.567	17.822	EPSD	TCGA;ICGC;COSMIC;GDSC;CCLE	16.403	Up-regulation
CAMK_CAMKL_LKB_STK11_ST	P04637	TP53	Q15831	STK11	T155	D148N	148	Missense	distal	-7	no	17.567	17.217	EPSD	TCGA;ICGC;COSMIC	16.403	Down-regulation
CAMK_CAMKL_LKB_STK11_ST	P04637	TP53	Q15831	STK11	T155	P151H	151	Missense	distal	-4	no	17.567	17.341	EPSD	TCGA;ICGC;COSMIC;GDSC;CCLE	16.403	Down-regulation
CAMK_CAMKL_LKB_STK11_ST	P04637	TP53	Q15831	STK11	T155	A161V	161	Missense	distal	6	no	17.567	17.451	EPSD	TCGA;ICGC;COSMIC	16.403	Down-regulation
CAMK_CAMKL_LKB_STK11_ST	P04637	TP53	Q15831	STK11	T155	A161S	161	Missense	distal	6	no	17.567	17.372	EPSD	TCGA;ICGC;COSMIC	16.403	Down-regulation
CAMK_CAMKL_LKB_STK11_ST	P04637	TP53	Q15831	STK11	T155	A159P	159	Missense	distal	4	no	17.567	16.584	EPSD	TCGA;ICGC;COSMIC;CCLE	16.403	Down-regulation
CAMK_CAMKL_LKB_STK11_ST	P04637	TP53	Q15831	STK11	T155	R158H	158	Missense	distal	3	no	17.567	18.696	EPSD	TCGA;ICGC;COSMIC;GDSC;CCLE	16.403	Up-regulation
CAMK_CAMKL_LKB_STK11_ST	P04637	TP53	Q15831	STK11	T155	P151A	151	Missense	distal	-4	no	17.567	17.552	EPSD	TCGA;ICGC;COSMIC;CCLE	16.403	Down-regulation
CAMK_CAMKL_LKB_STK11_ST	P04637	TP53	Q15831	STK11	T155	R156P	156	Missense	proximal	1	no	17.567	17.568	EPSD	TCGA;ICGC;COSMIC;GDSC;CCLE	16.403	Up-regulation
CAMK_CAMKL_LKB_STK11_ST	P04637	TP53	Q15831	STK11	T155	P151S	151	Missense	distal	-4	no	17.567	17.077	EPSD	TCGA;ICGC;COSMIC;GDSC;CCLE	16.403	Down-regulation
CAMK_CAMKL_LKB_STK11_ST	P04637	TP53	Q15831	STK11	T155	R158G	158	Missense	distal	3	no	17.567	24.052	EPSD	TCGA;ICGC;COSMIC;GDSC;CCLE	16.403	Up-regulation
CAMK_CAMKL_LKB_STK11_ST	P04637	TP53	Q15831	STK11	T155	V157F	157	Missense	proximal	2	no	17.567	13.038	EPSD	TCGA;ICGC;COSMIC;GDSC;CCLE	16.403	Loss
CAMK_CAMKL_LKB_STK11_ST	P04637	TP53	Q15831	STK11	T155	V157G	157	Missense	proximal	2	no	17.567	13.248	EPSD	TCGA;ICGC;COSMIC	16.403	Loss
CAMK_CAMKL_LKB_STK11_ST	P04637	TP53	Q15831	STK11	T155	V157D	157	Missense	proximal	2	no	17.567	20.087	EPSD	TCGA;ICGC;COSMIC	16.403	Up-regulation
CAMK_CAMKL_LKB_STK11_ST	P04637	TP53	Q15831	STK11	T155	I162N	162	Missense	distal	7	no	17.567	17.334	EPSD	TCGA;ICGC;COSMIC;GDSC;CCLE	16.403	Down-regulation
CAMK_CAMKL_LKB_STK11_ST	P04637	TP53	Q15831	STK11	T155	T155I	155	Missense	central	0	yes	17.567	0.000	EPSD	TCGA;ICGC;COSMIC;CCLE	16.403	Loss
CAMK_CAMKL_LKB_STK11_ST	P04637	TP53	Q15831	STK11	T155	R158L	158	Missense	distal	3	no	17.567	11.084	EPSD	TCGA;ICGC;COSMIC;GDSC;CCLE	16.403	Loss
CAMK_CAMKL_LKB_STK11_ST	P04637	TP53	Q15831	STK11	T155	T155N	155	Missense	central	0	yes	17.567	0.000	EPSD	TCGA;ICGC;COSMIC;GDSC;CCLE	16.403	Loss
CAMK_CAMKL_LKB_STK11_ST	P04637	TP53	Q15831	STK11	T155	P152S	152	Missense	distal	-3	no	17.567	17.750	EPSD	TCGA;ICGC;COSMIC;CCLE	16.403	Up-regulation
CAMK_CAMKL_LKB_STK11_ST	P04637	TP53	Q15831	STK11	T155	R156C	156	Missense	proximal	1	no	17.567	17.584	EPSD	TCGA;ICGC;COSMIC	16.403	Up-regulation
CAMK_CAMKL_LKB_STK11_ST	P04637	TP53	Q15831	STK11	T155	P151T	151	Missense	distal	-4	no	17.567	17.544	EPSD	TCGA;ICGC;COSMIC	16.403	Down-regulation
CAMK_CAMKL_LKB_STK11_ST	P04637	TP53	Q15831	STK11	T155	T155P	155	Missense	central	0	yes	17.567	0.000	EPSD	TCGA;ICGC;COSMIC;CCLE	16.403	Loss
CAMK_CAMKL_LKB_STK11_ST	P04637	TP53	Q15831	STK11	T155	R158S	158	Missense	distal	3	no	17.567	13.892	EPSD	TCGA;ICGC;COSMIC	16.403	Loss
CAMK_CAMKL_LKB_STK11_ST	P04637	TP53	Q15831	STK11	T155	P152Q	152	Missense	distal	-3	no	17.567	17.600	EPSD	TCGA;ICGC;COSMIC	16.403	Up-regulation
CAMK_CAMKL_LKB_STK11_ST	P04637	TP53	Q15831	STK11	T155	R156H	156	Missense	proximal	1	no	17.567	17.579	EPSD	TCGA;ICGC;COSMIC	16.403	Up-regulation
CAMK_CAMKL_LKB_STK11_ST	P04637	TP53	Q15831	STK11	T155	R158P	158	Missense	distal	3	no	17.567	20.529	EPSD	TCGA;ICGC;COSMIC;GDSC;CCLE	16.403	Up-regulation
CAMK_CAMKL_LKB_STK11_ST	P04637	TP53	Q15831	STK11	T155	G154V	154	Missense	proximal	-1	no	17.567	17.561	EPSD	TCGA;ICGC;COSMIC;GDSC;CCLE	16.403	Down-regulation
CAMK_CAMKL_LKB_STK11_ST	P04637	TP53	Q15831	STK11	T155	V157L	157	Missense	proximal	2	no	17.567	13.423	EPSD	TCGA;ICGC;COSMIC	16.403	Loss
CAMK_CAMKL_LKB_STK11_ST	P04637	TP53	Q15831	STK11	T155	A161D	161	Missense	distal	6	no	17.567	20.302	EPSD	TCGA;ICGC;COSMIC;GDSC;CCLE	16.403	Up-regulation
CAMK_CAMKL_LKB_STK11_ST	P04637	TP53	Q15831	STK11	T155	P151R	151	Missense	distal	-4	no	17.567	16.957	EPSD	TCGA;ICGC;COSMIC	16.403	Down-regulation
CAMK_CAMKL_LKB_STK11_ST	P04637	TP53	Q15831	STK11	T155	M160I	160	Missense	distal	5	no	17.567	17.122	EPSD	TCGA;ICGC;COSMIC	16.403	Down-regulation
CAMK_CAMKL_LKB_STK11_ST	P04637	TP53	Q15831	STK11	T155	R156G	156	Missense	proximal	1	no	17.567	17.575	EPSD	TCGA;ICGC;COSMIC	16.403	Up-regulation
CAMK_CAMKL_LKB_STK11_ST	P04637	TP53	Q15831	STK11	T155	A161P	161	Missense	distal	6	no	17.567	18.892	EPSD	TCGA;ICGC;COSMIC	16.403	Up-regulation
CAMK_CAMKL_LKB_STK11_ST	P04637	TP53	Q15831	STK11	T155	P151L	151	Missense	distal	-4	no	17.567	16.928	EPSD	TCGA;ICGC;COSMIC	16.403	Down-regulation
CAMK_CAMKL_LKB_STK11_ST	P04637	TP53	Q15831	STK11	T155	I162F	162	Missense	distal	7	no	17.567	17.237	EPSD	TCGA;ICGC;COSMIC	16.403	Down-regulation
CAMK_CAMKL_LKB_STK11_ST	P04637	TP53	Q15831	STK11	T155	R158C	158	Missense	distal	3	no	17.567	16.404	EPSD	TCGA;ICGC;COSMIC	16.403	Down-regulation
CAMK_CAMKL_LKB_STK11_ST	P46937	YAP1	Q15831	STK11	T143	S138F	138	Missense	distal	-5	no	30.334	30.764	EPSD	TCGA;ICGC;COSMIC	16.403	Up-regulation
CAMK_CAMKL_LKB_STK11_ST	P46937	YAP1	Q15831	STK11	T143	G140E	140	Missense	distal	-3	no	30.334	30.521	EPSD	TCGA;ICGC	16.403	Up-regulation
CAMK_CAMKL_LKB_STK11_ST	P46937	YAP1	Q15831	STK11	S163	Q158H	158	Missense	distal	-5	no	16.377	17.321	EPSD	TCGA;ICGC;COSMIC	16.403	Gain
CAMK_CAMKL_LKB_STK11_ST	P46937	YAP1	Q15831	STK11	S350	Q344K	344	Missense	distal	-6	no	28.145	28.102	EPSD	TCGA;ICGC;COSMIC	16.403	Down-regulation
CAMK_CAMKL_LKB_STK11_ST	P46937	YAP1	Q15831	STK11	T398	E396D	396	Missense	proximal	-2	no	22.358	22.380	EPSD	TCGA;ICGC;COSMIC	16.403	Up-regulation
CAMK_CAMKL_LKB_STK11_ST	P46937	YAP1	Q15831	STK11	T412	P413Q	413	Missense	proximal	1	no	19.292	19.299	EPSD	TCGA;ICGC;COSMIC	16.403	Up-regulation
CAMK_CAMKL_LKB_STK11_ST	P46937	YAP1	Q15831	STK11	T425	E422D	422	Missense	distal	-3	no	27.793	27.773	EPSD	TCGA;COSMIC	16.403	Down-regulation
CAMK_CAMKL_LKB_STK11_ST	Q9H0K1	SIK2	Q15831	STK11	T175	G170D	170	Missense	distal	-5	no	60.719	60.758	PhosphoSitePlus	TCGA;ICGC;COSMIC	16.403	Up-regulation
CAMK_CAMKL_LKB_STK11_ST	Q9H0K1	SIK2	Q15831	STK11	T458	E454K	454	Missense	distal	-4	no	19.538	19.613	EPSD	TCGA;ICGC;COSMIC	16.403	Up-regulation
CAMK_CAMKL_LKB_STK11_ST	Q9H0K1	SIK2	Q15831	STK11	T458	E463K	463	Missense	distal	5	no	19.538	18.565	EPSD	TCGA;ICGC;COSMIC	16.403	Down-regulation
CAMK_CAMKL_LKB_STK11_ST	Q9H0K1	SIK2	Q15831	STK11	T476	R477H	477	Missense	proximal	1	no	20.870	20.882	EPSD	TCGA;ICGC;COSMIC	16.403	Up-regulation
CAMK_CAMKL_LKB_STK11_ST	Q7KZI7	MARK2	Q15831	STK11	T201	F194C	194	Missense	distal	-7	no	21.453	21.439	EPSD	TCGA	16.403	Down-regulation
CAMK_CAMKL_LKB_STK11_ST	Q7KZI7	MARK2	Q15831	STK11	T201	K205Q	205	Missense	distal	4	no	21.453	20.710	EPSD	TCGA;COSMIC	16.403	Down-regulation
CAMK_CAMKL_LKB_STK11_ST	Q7KZI7	MARK2	Q15831	STK11	T201	K205N	205	Missense	distal	4	no	21.453	21.612	EPSD	TCGA;COSMIC	16.403	Up-regulation
CAMK_CAMKL_LKB_STK11_ST	Q7KZI7	MARK2	Q15831	STK11	T208	K205Q	205	Missense	distal	-3	no	62.070	61.831	PhosphoSitePlus	TCGA;COSMIC	16.403	Down-regulation
CAMK_CAMKL_LKB_STK11_ST	Q7KZI7	MARK2	Q15831	STK11	T208	K205N	205	Missense	distal	-3	no	62.070	61.935	PhosphoSitePlus	TCGA;COSMIC	16.403	Down-regulation
CAMK_CAMKL_LKB_STK11_ST	Q7KZI7	MARK2	Q15831	STK11	T208	P213L	213	Missense	distal	5	no	62.070	61.933	PhosphoSitePlus	TCGA;ICGC;COSMIC	16.403	Down-regulation
CAMK_CAMKL_LKB_STK11_ST	Q7KZI7	MARK2	Q15831	STK11	S212	K205Q	205	Missense	distal	-7	no	22.455	21.464	EPSD	TCGA;COSMIC	16.403	Down-regulation
CAMK_CAMKL_LKB_STK11_ST	Q7KZI7	MARK2	Q15831	STK11	S212	K205N	205	Missense	distal	-7	no	22.455	22.178	EPSD	TCGA;COSMIC	16.403	Down-regulation
CAMK_CAMKL_LKB_STK11_ST	Q7KZI7	MARK2	Q15831	STK11	S212	P213L	213	Missense	proximal	1	no	22.455	22.462	EPSD	TCGA;ICGC;COSMIC	16.403	Up-regulation
CAMK_CAMKL_LKB_STK11_ST	Q7KZI7	MARK2	Q15831	STK11	T338	E341D	341	Missense	distal	3	no	13.549	17.834	EPSD	TCGA;COSMIC	16.403	Gain
CAMK_CAMKL_LKB_STK11_ST	Q7KZI7	MARK2	Q15831	STK11	T384	A388V	388	Missense	distal	4	no	26.200	25.815	EPSD	TCGA;COSMIC	16.403	Down-regulation
CAMK_CAMKL_LKB_STK11_ST	Q7KZI7	MARK2	Q15831	STK11	T384	S390Y	390	Missense	distal	6	no	26.200	25.987	EPSD	TCGA;ICGC;COSMIC	16.403	Down-regulation
CAMK_CAMKL_LKB_STK11_ST	Q7KZI7	MARK2	Q15831	STK11	T384	A388S	388	Missense	distal	4	no	26.200	25.205	EPSD	TCGA;ICGC;COSMIC	16.403	Down-regulation
CAMK_CAMKL_LKB_STK11_ST	Q7KZI7	MARK2	Q15831	STK11	T384	A388T	388	Missense	distal	4	no	26.200	25.817	EPSD	TCGA;COSMIC	16.403	Down-regulation
CAMK_CAMKL_LKB_STK11_ST	Q7KZI7	MARK2	Q15831	STK11	S571	P566S	566	Missense	distal	-5	no	21.105	19.623	EPSD	TCGA;COSMIC	16.403	Down-regulation
CAMK_CAMKL_LKB_STK11_ST	Q7KZI7	MARK2	Q15831	STK11	S571	A572T	572	Missense	proximal	1	no	21.105	21.124	EPSD	TCGA;COSMIC	16.403	Up-regulation
CAMK_CAMKL_LKB_STK11_ST	Q9NRH2	SNRK	Q15831	STK11	T157	K164R	164	Missense	distal	7	no	27.664	27.692	EPSD	TCGA;ICGC	16.403	Up-regulation
CAMK_CAMKL_LKB_STK11_ST	Q9NRH2	SNRK	Q15831	STK11	T157	K164T	164	Missense	distal	7	no	27.664	28.426	EPSD	TCGA;ICGC;COSMIC	16.403	Up-regulation
CAMK_CAMKL_LKB_STK11_ST	Q9NRH2	SNRK	Q15831	STK11	T157	N163D	163	Missense	distal	6	no	27.664	29.659	EPSD	TCGA;ICGC;COSMIC	16.403	Up-regulation
CAMK_CAMKL_LKB_STK11_ST	Q9NRH2	SNRK	Q15831	STK11	T173	C175Y	175	Missense	proximal	2	no	41.986	36.834	PhosphoSitePlus	TCGA;ICGC;COSMIC	16.403	Down-regulation
CAMK_CAMKL_LKB_STK11_ST	Q9NRH2	SNRK	Q15831	STK11	T173	G168W	168	Missense	distal	-5	no	41.986	41.105	PhosphoSitePlus	TCGA;ICGC	16.403	Down-regulation
CAMK_CAMK2_CAMK2D_ST	P55327	TPD52	Q13557-8	CAMK2D	S35	P37L	37	Missense	proximal	2	no	36.236	40.105	EPSD	TCGA;ICGC;COSMIC	37.605	Gain
CAMK_CAMK2_CAMK2D_ST	P55327	TPD52	Q13557-8	CAMK2D	T64	A63S	63	Missense	proximal	-1	no	45.209	46.706	EPSD	TCGA;ICGC;COSMIC	37.605	Up-regulation
CAMK_CAMK2_CAMK2D_ST	P55327	TPD52	Q13557-8	CAMK2D	S176	V181A	181	Missense	distal	5	no	76.022	76.234	PhosphoSitePlus	TCGA;COSMIC	37.605	Up-regulation
CAMK_CAMK2_CAMK2D_ST	P55327	TPD52	Q13557-8	CAMK2D	S176	N183Y	183	Missense	distal	7	no	76.022	77.124	PhosphoSitePlus	TCGA;ICGC;COSMIC	37.605	Up-regulation
CAMK_CAMK2_CAMK2D_ST	P55327	TPD52	Q13557-8	CAMK2D	S176	K180T	180	Missense	distal	4	no	76.022	74.517	PhosphoSitePlus	TCGA;ICGC;COSMIC	37.605	Down-regulation
CAMK_CAMK2_CAMK2D_ST	P55327	TPD52	Q13557-8	CAMK2D	S176	T173S	173	Missense	distal	-3	no	76.022	81.479	PhosphoSitePlus	TCGA;ICGC;COSMIC	37.605	Up-regulation
CAMK_CAMK2_CAMK2D_ST	P55327	TPD52	Q13557-8	CAMK2D	S176	E182K	182	Missense	distal	6	no	76.022	76.569	PhosphoSitePlus	TCGA;COSMIC	37.605	Up-regulation
CAMK_CAMKL_MARK_MARK1_ST	P10636	MAPT	Q9P0L2	MARK1	T71	A77V	77	Missense	distal	6	no	0.253	0.249	EPSD	TCGA;ICGC	0.230	Down-regulation
CAMK_CAMKL_MARK_MARK1_ST	P10636	MAPT	Q9P0L2	MARK1	T71	A72V	72	Missense	proximal	1	no	0.253	0.263	EPSD	TCGA;ICGC;COSMIC	0.230	Up-regulation
CAMK_CAMKL_MARK_MARK1_ST	P10636	MAPT	Q9P0L2	MARK1	T71	A66S	66	Missense	distal	-5	no	0.253	0.250	EPSD	TCGA;ICGC;COSMIC	0.230	Down-regulation
CAMK_CAMKL_MARK_MARK1_ST	P10636	MAPT	Q9P0L2	MARK1	S228	S232Y	232	Missense	distal	4	no	0.334	0.256	EPSD	TCGA;ICGC;COSMIC	0.230	Down-regulation
CAMK_CAMKL_MARK_MARK1_ST	P10636	MAPT	Q9P0L2	MARK1	S228	D223Y	223	Missense	distal	-5	no	0.334	0.332	EPSD	TCGA;ICGC;COSMIC	0.230	Down-regulation
CAMK_CAMKL_MARK_MARK1_ST	P10636	MAPT	Q9P0L2	MARK1	S228	S227F	227	Missense	proximal	-1	no	0.334	0.332	EPSD	TCGA;ICGC;COSMIC	0.230	Down-regulation
CAMK_CAMKL_MARK_MARK1_ST	P10636	MAPT	Q9P0L2	MARK1	S228	P234L	234	Missense	distal	6	no	0.334	0.316	EPSD	TCGA;ICGC;COSMIC	0.230	Down-regulation
CAMK_CAMKL_MARK_MARK1_ST	P10636	MAPT	Q9P0L2	MARK1	S388	G387R	387	Missense	proximal	-1	no	0.258	0.260	EPSD	TCGA;COSMIC	0.230	Up-regulation
CAMK_CAMKL_MARK_MARK1_ST	P10636	MAPT	Q9P0L2	MARK1	S411	P415L	415	Missense	distal	4	no	0.197	0.268	EPSD	TCGA;ICGC;COSMIC	0.230	Gain
CAMK_CAMKL_MARK_MARK1_ST	P10636	MAPT	Q9P0L2	MARK1	S447	K440E	440	Missense	distal	-7	no	0.378	0.364	EPSD	TCGA;ICGC;COSMIC	0.230	Down-regulation
CAMK_CAMKL_MARK_MARK1_ST	P10636	MAPT	Q9P0L2	MARK1	S447	S452C	452	Missense	distal	5	no	0.378	0.382	EPSD	TCGA;ICGC;COSMIC	0.230	Up-regulation
CAMK_CAMKL_MARK_MARK1_ST	P10636	MAPT	Q9P0L2	MARK1	S447	S443F	443	Missense	distal	-4	no	0.378	0.311	EPSD	TCGA;ICGC;COSMIC	0.230	Down-regulation
CAMK_CAMKL_MARK_MARK1_ST	P10636	MAPT	Q9P0L2	MARK1	S447	S444F	444	Missense	distal	-3	no	0.378	0.371	EPSD	TCGA;ICGC	0.230	Down-regulation
CAMK_CAMKL_MARK_MARK1_ST	P10636	MAPT	Q9P0L2	MARK1	S447	S452Y	452	Missense	distal	5	no	0.378	0.431	EPSD	TCGA;ICGC;COSMIC	0.230	Up-regulation
CAMK_CAMKL_MARK_MARK1_ST	Q155Q3	DIXDC1	Q9P0L2	MARK1	S186	E192G	192	Missense	distal	6	no	0.218	0.233	EPSD	TCGA;ICGC;COSMIC	0.230	Gain
CAMK_CAMKL_MARK_MARK1_ST	Q155Q3	DIXDC1	Q9P0L2	MARK1	S186	Q182H	182	Missense	distal	-4	no	0.218	0.238	EPSD	TCGA;ICGC	0.230	Gain
CAMK_CAMKL_MARK_MARK1_ST	Q155Q3	DIXDC1	Q9P0L2	MARK1	S228	S228N	228	Missense	central	0	yes	0.254	0.000	EPSD	TCGA;COSMIC	0.230	Loss
CAMK_CAMKL_MARK_MARK1_ST	Q155Q3	DIXDC1	Q9P0L2	MARK1	S228	S233F	233	Missense	distal	5	no	0.254	0.307	EPSD	TCGA	0.230	Up-regulation
CAMK_CAMKL_MARK_MARK1_ST	Q155Q3	DIXDC1	Q9P0L2	MARK1	S238	V245A	245	Missense	distal	7	no	0.253	0.250	EPSD	TCGA;COSMIC	0.230	Down-regulation
CAMK_CAMKL_MARK_MARK1_ST	Q155Q3	DIXDC1	Q9P0L2	MARK1	S238	S233F	233	Missense	distal	-5	no	0.253	0.245	EPSD	TCGA	0.230	Down-regulation
CAMK_CAMKL_MARK_MARK1_ST	Q99689	FEZ1	Q9P0L2	MARK1	S55	E52K	52	Missense	distal	-3	no	0.233	0.243	EPSD	TCGA;ICGC;COSMIC	0.230	Up-regulation
CAMK_CAMKL_MARK_MARK1_ST	Q99689	FEZ1	Q9P0L2	MARK1	S55	S55I	55	Missense	central	0	yes	0.233	0.000	EPSD	TCGA;ICGC;COSMIC	0.230	Loss
CAMK_CAMKL_MARK_MARK1_ST	Q99689	FEZ1	Q9P0L2	MARK1	S58	E52K	52	Missense	distal	-6	no	0.487	0.468	PhosphoSitePlus	TCGA;ICGC;COSMIC	0.230	Down-regulation
CAMK_CAMKL_MARK_MARK1_ST	Q99689	FEZ1	Q9P0L2	MARK1	S58	V63I	63	Missense	distal	5	no	0.487	0.438	PhosphoSitePlus	TCGA;ICGC;COSMIC	0.230	Down-regulation
CAMK_CAMKL_MARK_MARK1_ST	Q99689	FEZ1	Q9P0L2	MARK1	S58	S55I	55	Missense	distal	-3	no	0.487	0.486	PhosphoSitePlus	TCGA;ICGC;COSMIC	0.230	Down-regulation
CAMK_CAMKL_MARK_MARK1_ST	Q99689	FEZ1	Q9P0L2	MARK1	S58	N64T	64	Missense	distal	6	no	0.487	0.472	PhosphoSitePlus	TCGA;ICGC;COSMIC	0.230	Down-regulation
CAMK_CAMKL_MARK_MARK1_ST	Q99689	FEZ1	Q9P0L2	MARK1	S58	L62I	62	Missense	distal	4	no	0.487	0.526	PhosphoSitePlus	TCGA;ICGC;COSMIC	0.230	Up-regulation
CAMK_CAMKL_MARK_MARK1_ST	Q99689	FEZ1	Q9P0L2	MARK1	S247	Q252L	252	Missense	distal	5	no	0.229	0.265	EPSD	TCGA;ICGC;COSMIC	0.230	Gain
CAMK_CAMKL_MARK_MARK1_ST	Q99689	FEZ1	Q9P0L2	MARK1	S247	Q253R	253	Missense	distal	6	no	0.229	0.238	EPSD	TCGA	0.230	Gain
CAMK_CAMKL_MARK_MARK1_ST	Q99689	FEZ1	Q9P0L2	MARK1	S316	N322T	322	Missense	distal	6	no	0.301	0.287	EPSD	TCGA;ICGC;COSMIC	0.230	Down-regulation
CAMK_CAMKL_MARK_MARK1_ST	Q99689	FEZ1	Q9P0L2	MARK1	S316	R314H	314	Missense	proximal	-2	no	0.301	0.305	EPSD	TCGA	0.230	Up-regulation
AGC_GRK_GRK_GRK7_ST	Q16625	OCLN	Q8WTQ7	GRK7	S3	S3C	3	Missense	central	0	yes	1.539	0.000	EPSD	TCGA;COSMIC	1.098	Loss
AGC_GRK_GRK_GRK7_ST	Q16625	OCLN	Q8WTQ7	GRK7	S3	P9S	9	Missense	distal	6	no	1.539	1.325	EPSD	TCGA;ICGC;COSMIC	1.098	Down-regulation
AGC_GRK_GRK_GRK7_ST	Q16625	OCLN	Q8WTQ7	GRK7	T376	G371D	371	Missense	distal	-5	no	1.086	1.365	EPSD	TCGA;ICGC	1.098	Gain
Other_ULK_ULK_ULK3_ST	Q6PHR2	ULK3	Q6PHR2	ULK3	S350	N352S	352	Missense	proximal	2	no	4.739	4.785	EPSD;PhosphoSitePlus	TCGA;COSMIC	1.534	Up-regulation
Other_ULK_ULK_ULK3_ST	Q6PHR2	ULK3	Q6PHR2	ULK3	S350	E343K	343	Missense	distal	-7	no	4.739	4.768	EPSD;PhosphoSitePlus	TCGA;COSMIC	1.534	Up-regulation
Other_ULK_ULK_ULK3_ST	Q6PHR2	ULK3	Q6PHR2	ULK3	S350	S351F	351	Missense	proximal	1	no	4.739	4.552	EPSD;PhosphoSitePlus	TCGA;COSMIC	1.534	Down-regulation
Other_ULK_ULK_ULK3_ST	Q6PHR2	ULK3	Q6PHR2	ULK3	S350	L344P	344	Missense	distal	-6	no	4.739	4.730	EPSD;PhosphoSitePlus	TCGA;COSMIC	1.534	Down-regulation
CAMK_CAMKL_MARK_MARK2_ST	Q8WUI4	HDAC7	Q7KZI7	MARK2	S573	S573F	573	Missense	central	0	yes	330.402	0.000	EPSD	TCGA;COSMIC	271.430	Loss
CAMK_CAMKL_MARK_MARK2_ST	P56524	HDAC4	Q7KZI7	MARK2	S58	D54N	54	Missense	distal	-4	no	270.020	271.881	EPSD	TCGA;COSMIC	271.430	Gain
CAMK_CAMKL_MARK_MARK2_ST	P56524	HDAC4	Q7KZI7	MARK2	S224	P228L	228	Missense	distal	4	no	145.307	273.886	EPSD	TCGA;COSMIC	271.430	Gain
CAMK_CAMKL_MARK_MARK2_ST	P56524	HDAC4	Q7KZI7	MARK2	T244	P248L	248	Missense	distal	4	no	205.545	334.124	EPSD	TCGA;COSMIC	271.430	Gain
CAMK_CAMKL_MARK_MARK2_ST	P56524	HDAC4	Q7KZI7	MARK2	S246	L241F	241	Missense	distal	-5	no	407.942	405.293	PhosphoSitePlus	TCGA;COSMIC	271.430	Down-regulation
CAMK_CAMKL_MARK_MARK2_ST	P56524	HDAC4	Q7KZI7	MARK2	S246	R253W	253	Missense	distal	7	no	407.942	372.270	PhosphoSitePlus	TCGA;COSMIC	271.430	Down-regulation
CAMK_CAMKL_MARK_MARK2_ST	P56524	HDAC4	Q7KZI7	MARK2	S246	P248L	248	Missense	proximal	2	no	407.942	389.547	PhosphoSitePlus	TCGA;COSMIC	271.430	Down-regulation
CAMK_CAMKL_MARK_MARK2_ST	P56524	HDAC4	Q7KZI7	MARK2	S246	R242G	242	Missense	distal	-4	no	407.942	406.101	PhosphoSitePlus	TCGA;COSMIC	271.430	Down-regulation
CAMK_CAMKL_MARK_MARK2_ST	P56524	HDAC4	Q7KZI7	MARK2	S266	R270C	270	Missense	distal	4	no	325.486	311.482	EPSD	TCGA;COSMIC;CCLE	271.430	Down-regulation
CAMK_CAMKL_MARK_MARK2_ST	P56524	HDAC4	Q7KZI7	MARK2	S266	R263K	263	Missense	distal	-3	no	325.486	317.837	EPSD	TCGA;COSMIC	271.430	Down-regulation
CAMK_CAMKL_MARK_MARK2_ST	P56524	HDAC4	Q7KZI7	MARK2	S293	S290F	290	Missense	distal	-3	no	292.315	286.942	EPSD	TCGA;COSMIC	271.430	Down-regulation
CAMK_CAMKL_MARK_MARK2_ST	P56524	HDAC4	Q7KZI7	MARK2	S293	A295T	295	Missense	proximal	2	no	292.315	301.129	EPSD	TCGA;COSMIC	271.430	Up-regulation
CAMK_CAMKL_MARK_MARK2_ST	P56524	HDAC4	Q7KZI7	MARK2	S293	P300S	300	Missense	distal	7	no	292.315	286.383	EPSD	TCGA;COSMIC	271.430	Down-regulation
CAMK_CAMKL_MARK_MARK2_ST	P56524	HDAC4	Q7KZI7	MARK2	S293	G299R	299	Missense	distal	6	no	292.315	289.437	EPSD	TCGA;COSMIC	271.430	Down-regulation
CAMK_CAMKL_MARK_MARK2_ST	P56524	HDAC4	Q7KZI7	MARK2	S302	S309N	309	Missense	distal	7	no	253.002	271.962	EPSD	TCGA;COSMIC	271.430	Gain
CAMK_CAMKL_MARK_MARK2_ST	P56524	HDAC4	Q7KZI7	MARK2	S302	S306N	306	Missense	distal	4	no	253.002	340.101	EPSD	TCGA	271.430	Gain
CAMK_CAMKL_MARK_MARK2_ST	P56524	HDAC4	Q7KZI7	MARK2	S302	G299R	299	Missense	distal	-3	no	253.002	299.304	EPSD	TCGA;COSMIC	271.430	Gain
CAMK_CAMKL_MARK_MARK2_ST	P56524	HDAC4	Q7KZI7	MARK2	S306	S309N	309	Missense	distal	3	no	245.029	274.932	EPSD	TCGA;COSMIC	271.430	Gain
CAMK_CAMKL_MARK_MARK2_ST	P56524	HDAC4	Q7KZI7	MARK2	S307	A312V	312	Missense	distal	5	no	256.724	288.008	EPSD	TCGA;COSMIC	271.430	Gain
CAMK_CAMKL_MARK_MARK2_ST	P56524	HDAC4	Q7KZI7	MARK2	S309	A312V	312	Missense	distal	3	no	256.983	288.652	EPSD	TCGA;COSMIC	271.430	Gain
CAMK_CAMKL_MARK_MARK2_ST	P56524	HDAC4	Q7KZI7	MARK2	S309	S306N	306	Missense	distal	-3	no	256.983	285.939	EPSD	TCGA	271.430	Gain
CAMK_CAMKL_MARK_MARK2_ST	P56524	HDAC4	Q7KZI7	MARK2	S311	G315C	315	Missense	distal	4	no	290.073	215.712	EPSD	TCGA;COSMIC	271.430	Loss
CAMK_CAMKL_MARK_MARK2_ST	P56524	HDAC4	Q7KZI7	MARK2	S311	S309N	309	Missense	proximal	-2	no	290.073	290.615	EPSD	TCGA;COSMIC	271.430	Up-regulation
CAMK_CAMKL_MARK_MARK2_ST	P56524	HDAC4	Q7KZI7	MARK2	S311	A312V	312	Missense	proximal	1	no	290.073	300.538	EPSD	TCGA;COSMIC	271.430	Up-regulation
CAMK_CAMKL_MARK_MARK2_ST	P56524	HDAC4	Q7KZI7	MARK2	S311	S306N	306	Missense	distal	-5	no	290.073	310.079	EPSD	TCGA	271.430	Up-regulation
CAMK_CAMKL_MARK_MARK2_ST	P56524	HDAC4	Q7KZI7	MARK2	S311	V310I	310	Missense	proximal	-1	no	290.073	292.270	EPSD	TCGA;COSMIC	271.430	Up-regulation
CAMK_CAMKL_MARK_MARK2_ST	P56524	HDAC4	Q7KZI7	MARK2	S339	E337K	337	Missense	proximal	-2	no	319.764	319.079	EPSD	TCGA;COSMIC	271.430	Down-regulation
CAMK_CAMKL_MARK_MARK2_ST	P56524	HDAC4	Q7KZI7	MARK2	S348	P352L	352	Missense	distal	4	no	153.686	282.265	EPSD	TCGA;COSMIC	271.430	Gain
CAMK_CAMKL_MARK_MARK2_ST	P56524	HDAC4	Q7KZI7	MARK2	S584	E587Q	587	Missense	distal	3	no	303.735	289.433	EPSD	TCGA	271.430	Down-regulation
CAMK_CAMKL_MARK_MARK2_ST	P56524	HDAC4	Q7KZI7	MARK2	S584	R581C	581	Missense	distal	-3	no	303.735	210.928	EPSD	TCGA;COSMIC	271.430	Loss
CAMK_CAMKL_MARK_MARK2_ST	P56524	HDAC4	Q7KZI7	MARK2	S584	P578L	578	Missense	distal	-6	no	303.735	305.946	EPSD	TCGA;COSMIC	271.430	Up-regulation
CAMK_CAMKL_MARK_MARK2_ST	P56524	HDAC4	Q7KZI7	MARK2	S741	F746L	746	Missense	distal	5	no	266.738	283.584	EPSD	TCGA;COSMIC	271.430	Gain
CAMK_CAMKL_MARK_MARK2_ST	P56524	HDAC4	Q7KZI7	MARK2	S1061	A1058V	1058	Missense	distal	-3	no	238.006	291.931	EPSD	TCGA;COSMIC	271.430	Gain
CAMK_CAMKL_MARK_MARK2_ST	Q8TEW0	PARD3	Q7KZI7	MARK2	S144	P146L	146	Missense	proximal	2	no	396.547	378.152	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	271.430	Down-regulation
CAMK_CAMKL_MARK_MARK2_ST	Q8TEW0	PARD3	Q7KZI7	MARK2	S174	P170S	170	Missense	distal	-4	no	283.019	276.772	EPSD	TCGA;ICGC;COSMIC	271.430	Down-regulation
CAMK_CAMKL_MARK_MARK2_ST	Q8TEW0	PARD3	Q7KZI7	MARK2	S174	R172C	172	Missense	proximal	-2	no	283.019	285.671	EPSD	TCGA;ICGC;COSMIC	271.430	Up-regulation
CAMK_CAMKL_MARK_MARK2_ST	Q8TEW0	PARD3	Q7KZI7	MARK2	T175	Q182E	182	Missense	distal	7	no	276.209	284.131	EPSD	TCGA;ICGC;COSMIC	271.430	Up-regulation
CAMK_CAMKL_MARK_MARK2_ST	Q8TEW0	PARD3	Q7KZI7	MARK2	T175	P170S	170	Missense	distal	-5	no	276.209	276.652	EPSD	TCGA;ICGC;COSMIC	271.430	Up-regulation
CAMK_CAMKL_MARK_MARK2_ST	Q8TEW0	PARD3	Q7KZI7	MARK2	T175	R172C	172	Missense	distal	-3	no	276.209	183.402	EPSD	TCGA;ICGC;COSMIC	271.430	Loss
CAMK_CAMKL_MARK_MARK2_ST	Q8TEW0	PARD3	Q7KZI7	MARK2	S201	Y199C	199	Missense	proximal	-2	no	277.002	281.668	EPSD	TCGA;ICGC;COSMIC	271.430	Up-regulation
CAMK_CAMKL_MARK_MARK2_ST	Q8TEW0	PARD3	Q7KZI7	MARK2	S225	K231N	231	Missense	distal	6	no	268.273	272.578	EPSD	TCGA;ICGC;COSMIC	271.430	Gain
CAMK_CAMKL_MARK_MARK2_ST	Q8TEW0	PARD3	Q7KZI7	MARK2	S396	R392K	392	Missense	distal	-4	no	301.893	299.526	EPSD	TCGA;ICGC;COSMIC	271.430	Down-regulation
CAMK_CAMKL_MARK_MARK2_ST	Q8TEW0	PARD3	Q7KZI7	MARK2	S396	N391S	391	Missense	distal	-5	no	301.893	281.886	EPSD	TCGA;ICGC	271.430	Down-regulation
CAMK_CAMKL_MARK_MARK2_ST	Q8TEW0	PARD3	Q7KZI7	MARK2	S417	Q414H	414	Missense	distal	-3	no	195.944	275.008	EPSD	TCGA;ICGC;COSMIC	271.430	Gain
CAMK_CAMKL_MARK_MARK2_ST	Q8TEW0	PARD3	Q7KZI7	MARK2	T446	Y451H	451	Missense	distal	5	no	295.550	293.452	EPSD	TCGA;ICGC;COSMIC	271.430	Down-regulation
CAMK_CAMKL_MARK_MARK2_ST	Q8TEW0	PARD3	Q7KZI7	MARK2	T446	Y451C	451	Missense	distal	5	no	295.550	282.598	EPSD	TCGA;ICGC;COSMIC	271.430	Down-regulation
CAMK_CAMKL_MARK_MARK2_ST	Q8TEW0	PARD3	Q7KZI7	MARK2	T453	Y451H	451	Missense	proximal	-2	no	281.736	283.518	EPSD	TCGA;ICGC;COSMIC	271.430	Up-regulation
CAMK_CAMKL_MARK_MARK2_ST	Q8TEW0	PARD3	Q7KZI7	MARK2	T453	G457C	457	Missense	distal	4	no	281.736	207.375	EPSD	TCGA;ICGC;COSMIC	271.430	Loss
CAMK_CAMKL_MARK_MARK2_ST	Q8TEW0	PARD3	Q7KZI7	MARK2	T453	Y451C	451	Missense	proximal	-2	no	281.736	286.401	EPSD	TCGA;ICGC;COSMIC	271.430	Up-regulation
CAMK_CAMKL_MARK_MARK2_ST	Q8TEW0	PARD3	Q7KZI7	MARK2	T468	Q463H	463	Missense	distal	-5	no	273.513	283.644	EPSD	TCGA;ICGC;COSMIC	271.430	Up-regulation
CAMK_CAMKL_MARK_MARK2_ST	Q8TEW0	PARD3	Q7KZI7	MARK2	T468	L464R	464	Missense	distal	-4	no	273.513	279.909	EPSD	TCGA;ICGC;COSMIC	271.430	Up-regulation
CAMK_CAMKL_MARK_MARK2_ST	Q8TEW0	PARD3	Q7KZI7	MARK2	T468	I462S	462	Missense	distal	-6	no	273.513	273.035	EPSD	TCGA;ICGC	271.430	Down-regulation
CAMK_CAMKL_MARK_MARK2_ST	Q8TEW0	PARD3	Q7KZI7	MARK2	S596	D595N	595	Missense	proximal	-1	no	364.172	364.366	EPSD	TCGA;ICGC;COSMIC	271.430	Up-regulation
CAMK_CAMKL_MARK_MARK2_ST	Q8TEW0	PARD3	Q7KZI7	MARK2	S596	L601F	601	Missense	distal	5	no	364.172	347.326	EPSD	TCGA;ICGC;COSMIC	271.430	Down-regulation
CAMK_CAMKL_MARK_MARK2_ST	Q8TEW0	PARD3	Q7KZI7	MARK2	S598	D595N	595	Missense	distal	-3	no	286.486	336.231	EPSD	TCGA;ICGC;COSMIC	271.430	Up-regulation
CAMK_CAMKL_MARK_MARK2_ST	Q8TEW0	PARD3	Q7KZI7	MARK2	S598	L601F	601	Missense	distal	3	no	286.486	257.475	EPSD	TCGA;ICGC;COSMIC	271.430	Loss
CAMK_CAMKL_MARK_MARK2_ST	Q8TEW0	PARD3	Q7KZI7	MARK2	S604	L601F	601	Missense	distal	-3	no	274.692	234.705	EPSD	TCGA;ICGC;COSMIC	271.430	Loss
CAMK_CAMKL_MARK_MARK2_ST	Q8TEW0	PARD3	Q7KZI7	MARK2	S667	S667C	667	Missense	central	0	yes	337.841	0.000	EPSD	TCGA;ICGC;COSMIC	271.430	Loss
CAMK_CAMKL_MARK_MARK2_ST	Q8TEW0	PARD3	Q7KZI7	MARK2	S685	E689G	689	Missense	distal	4	no	319.129	355.765	EPSD	TCGA;ICGC;COSMIC	271.430	Up-regulation
CAMK_CAMKL_MARK_MARK2_ST	Q8TEW0	PARD3	Q7KZI7	MARK2	S685	R682M	682	Missense	distal	-3	no	319.129	219.168	EPSD	TCGA;ICGC;COSMIC	271.430	Loss
CAMK_CAMKL_MARK_MARK2_ST	Q8TEW0	PARD3	Q7KZI7	MARK2	S715	R710K	710	Missense	distal	-5	no	266.133	272.050	EPSD	TCGA;ICGC;COSMIC	271.430	Gain
CAMK_CAMKL_MARK_MARK2_ST	Q8TEW0	PARD3	Q7KZI7	MARK2	S728	G721R	721	Missense	distal	-7	no	310.369	310.252	EPSD	TCGA;ICGC;COSMIC	271.430	Down-regulation
CAMK_CAMKL_MARK_MARK2_ST	Q8TEW0	PARD3	Q7KZI7	MARK2	S728	A733D	733	Missense	distal	5	no	310.369	321.154	EPSD	TCGA;ICGC	271.430	Up-regulation
CAMK_CAMKL_MARK_MARK2_ST	Q8TEW0	PARD3	Q7KZI7	MARK2	S730	A733D	733	Missense	distal	3	no	229.795	277.738	EPSD	TCGA;ICGC	271.430	Gain
CAMK_CAMKL_MARK_MARK2_ST	Q8TEW0	PARD3	Q7KZI7	MARK2	S807	C806W	806	Missense	proximal	-1	no	312.349	287.217	EPSD	TCGA;COSMIC	271.430	Down-regulation
CAMK_CAMKL_MARK_MARK2_ST	Q8TEW0	PARD3	Q7KZI7	MARK2	S807	D811A	811	Missense	distal	4	no	312.349	301.557	EPSD	TCGA;COSMIC	271.430	Down-regulation
CAMK_CAMKL_MARK_MARK2_ST	Q8TEW0	PARD3	Q7KZI7	MARK2	S807	I800N	800	Missense	distal	-7	no	312.349	312.262	EPSD	TCGA;COSMIC	271.430	Down-regulation
CAMK_CAMKL_MARK_MARK2_ST	Q8TEW0	PARD3	Q7KZI7	MARK2	S809	C806W	806	Missense	distal	-3	no	278.874	224.141	EPSD	TCGA;COSMIC	271.430	Loss
CAMK_CAMKL_MARK_MARK2_ST	Q8TEW0	PARD3	Q7KZI7	MARK2	S809	D811A	811	Missense	proximal	2	no	278.874	245.555	EPSD	TCGA;COSMIC	271.430	Loss
CAMK_CAMKL_MARK_MARK2_ST	Q8TEW0	PARD3	Q7KZI7	MARK2	S827	R820Q	820	Missense	distal	-7	no	299.784	299.871	EPSD	TCGA;COSMIC	271.430	Up-regulation
CAMK_CAMKL_MARK_MARK2_ST	Q8TEW0	PARD3	Q7KZI7	MARK2	S827	E821V	821	Missense	distal	-6	no	299.784	300.006	EPSD	TCGA;COSMIC	271.430	Up-regulation
CAMK_CAMKL_MARK_MARK2_ST	Q8TEW0	PARD3	Q7KZI7	MARK2	S827	R832H	832	Missense	distal	5	no	299.784	296.176	EPSD	TCGA;COSMIC	271.430	Down-regulation
CAMK_CAMKL_MARK_MARK2_ST	Q8TEW0	PARD3	Q7KZI7	MARK2	S827	R825C	825	Missense	proximal	-2	no	299.784	302.437	EPSD	TCGA	271.430	Up-regulation
CAMK_CAMKL_MARK_MARK2_ST	Q8TEW0	PARD3	Q7KZI7	MARK2	S827	G824E	824	Missense	distal	-3	no	299.784	225.912	EPSD	TCGA	271.430	Loss
CAMK_CAMKL_MARK_MARK2_ST	Q8TEW0	PARD3	Q7KZI7	MARK2	S852	G856S	856	Missense	distal	4	no	338.054	250.393	EPSD	TCGA;COSMIC	271.430	Loss
CAMK_CAMKL_MARK_MARK2_ST	Q8TEW0	PARD3	Q7KZI7	MARK2	S852	K849T	849	Missense	distal	-3	no	338.054	252.459	EPSD	TCGA;COSMIC	271.430	Loss
CAMK_CAMKL_MARK_MARK2_ST	Q8TEW0	PARD3	Q7KZI7	MARK2	S873	D867N	867	Missense	distal	-6	no	341.821	341.794	PhosphoSitePlus;EPSD	TCGA;COSMIC	271.430	Down-regulation
CAMK_CAMKL_MARK_MARK2_ST	Q8TEW0	PARD3	Q7KZI7	MARK2	S875	S881F	881	Missense	distal	6	no	281.356	284.088	EPSD	TCGA;COSMIC	271.430	Up-regulation
CAMK_CAMKL_MARK_MARK2_ST	Q8TEW0	PARD3	Q7KZI7	MARK2	S881	K885N	885	Missense	distal	4	no	271.305	309.988	EPSD	TCGA	271.430	Gain
CAMK_CAMKL_MARK_MARK2_ST	Q8TEW0	PARD3	Q7KZI7	MARK2	S887	S889T	889	Missense	proximal	2	no	300.286	269.918	EPSD	TCGA;COSMIC	271.430	Loss
CAMK_CAMKL_MARK_MARK2_ST	Q8TEW0	PARD3	Q7KZI7	MARK2	S887	S881F	881	Missense	distal	-6	no	300.286	299.497	EPSD	TCGA;COSMIC	271.430	Down-regulation
CAMK_CAMKL_MARK_MARK2_ST	Q8TEW0	PARD3	Q7KZI7	MARK2	S887	K885N	885	Missense	proximal	-2	no	300.286	303.451	EPSD	TCGA	271.430	Up-regulation
CAMK_CAMKL_MARK_MARK2_ST	Q8TEW0	PARD3	Q7KZI7	MARK2	S889	A896T	896	Missense	distal	7	no	325.266	338.558	EPSD	TCGA;COSMIC	271.430	Up-regulation
CAMK_CAMKL_MARK_MARK2_ST	Q8TEW0	PARD3	Q7KZI7	MARK2	S889	K885N	885	Missense	distal	-4	no	325.266	331.310	EPSD	TCGA	271.430	Up-regulation
CAMK_CAMKL_MARK_MARK2_ST	Q8TEW0	PARD3	Q7KZI7	MARK2	S1107	E1105K	1105	Missense	proximal	-2	no	293.283	292.597	EPSD	TCGA;COSMIC	271.430	Down-regulation
CAMK_CAMKL_MARK_MARK2_ST	Q8TEW0	PARD3	Q7KZI7	MARK2	S1107	M1108V	1108	Missense	proximal	1	no	293.283	303.107	EPSD	TCGA;COSMIC	271.430	Up-regulation
CAMK_CAMKL_MARK_MARK2_ST	Q8TEW0	PARD3	Q7KZI7	MARK2	S1107	L1110I	1110	Missense	distal	3	no	293.283	300.469	EPSD	TCGA;COSMIC	271.430	Up-regulation
CAMK_CAMKL_MARK_MARK2_ST	Q8TEW0	PARD3	Q7KZI7	MARK2	S1107	S1102Y	1102	Missense	distal	-5	no	293.283	297.123	EPSD	TCGA	271.430	Up-regulation
CAMK_CAMKL_MARK_MARK2_ST	Q8TEW0	PARD3	Q7KZI7	MARK2	S1116	M1123T	1123	Missense	distal	7	no	320.292	329.648	EPSD	TCGA;COSMIC	271.430	Up-regulation
CAMK_CAMKL_MARK_MARK2_ST	Q8TEW0	PARD3	Q7KZI7	MARK2	S1116	L1110I	1110	Missense	distal	-6	no	320.292	319.218	EPSD	TCGA;COSMIC	271.430	Down-regulation
CAMK_CAMKL_MARK_MARK2_ST	Q8TEW0	PARD3	Q7KZI7	MARK2	S1139	S1143G	1143	Missense	distal	4	no	194.774	282.436	EPSD	TCGA;COSMIC	271.430	Gain
CAMK_CAMKL_MARK_MARK2_ST	Q8TEW0	PARD3	Q7KZI7	MARK2	S1146	S1143G	1143	Missense	distal	-3	no	274.761	296.981	EPSD	TCGA;COSMIC	271.430	Up-regulation
CAMK_CAMKL_MARK_MARK2_ST	Q8TEW0	PARD3	Q7KZI7	MARK2	S1146	R1153L	1153	Missense	distal	7	no	274.761	273.622	EPSD	TCGA;COSMIC	271.430	Down-regulation
CAMK_CAMKL_MARK_MARK2_ST	Q8TEW0	PARD3	Q7KZI7	MARK2	S1146	R1153W	1153	Missense	distal	7	no	274.761	239.089	EPSD	TCGA;COSMIC;GDSC;CCLE	271.430	Loss
CAMK_CAMKL_MARK_MARK2_ST	Q8TEW0	PARD3	Q7KZI7	MARK2	S1146	R1153Q	1153	Missense	distal	7	no	274.761	257.511	EPSD	TCGA;COSMIC	271.430	Loss
CAMK_CAMKL_MARK_MARK2_ST	Q8TEW0	PARD3	Q7KZI7	MARK2	T1147	S1143G	1143	Missense	distal	-4	no	301.491	299.251	EPSD	TCGA;COSMIC	271.430	Down-regulation
CAMK_CAMKL_MARK_MARK2_ST	Q8TEW0	PARD3	Q7KZI7	MARK2	T1147	R1153L	1153	Missense	distal	6	no	301.491	309.530	EPSD	TCGA;COSMIC	271.430	Up-regulation
CAMK_CAMKL_MARK_MARK2_ST	Q8TEW0	PARD3	Q7KZI7	MARK2	T1147	R1153W	1153	Missense	distal	6	no	301.491	288.713	EPSD	TCGA;COSMIC;GDSC;CCLE	271.430	Down-regulation
CAMK_CAMKL_MARK_MARK2_ST	Q8TEW0	PARD3	Q7KZI7	MARK2	T1147	R1153Q	1153	Missense	distal	6	no	301.491	289.117	EPSD	TCGA;COSMIC	271.430	Down-regulation
CAMK_CAMKL_MARK_MARK2_ST	Q8TEW0	PARD3	Q7KZI7	MARK2	S1149	R1153L	1153	Missense	distal	4	no	271.305	329.535	EPSD	TCGA;COSMIC	271.430	Gain
CAMK_CAMKL_MARK_MARK2_ST	Q8TEW0	PARD3	Q7KZI7	MARK2	S1196	S1198F	1198	Missense	proximal	2	no	275.712	243.538	EPSD	TCGA;COSMIC	271.430	Loss
CAMK_CAMKL_MARK_MARK2_ST	Q8TEW0	PARD3	Q7KZI7	MARK2	S1196	Q1191H	1191	Missense	distal	-5	no	275.712	285.844	EPSD	TCGA;COSMIC;CCLE	271.430	Up-regulation
CAMK_CAMKL_MARK_MARK2_ST	Q8TEW0	PARD3	Q7KZI7	MARK2	S1196	S1196L	1196	Missense	central	0	yes	275.712	0.000	EPSD	TCGA	271.430	Loss
CAMK_CAMKL_MARK_MARK2_ST	Q8TEW0	PARD3	Q7KZI7	MARK2	S1196	V1199A	1199	Missense	distal	3	no	275.712	244.043	EPSD	TCGA;COSMIC	271.430	Loss
CAMK_CAMKL_MARK_MARK2_ST	Q8TEW0	PARD3	Q7KZI7	MARK2	S1196	H1195Y	1195	Missense	proximal	-1	no	275.712	257.731	EPSD	TCGA;COSMIC	271.430	Loss
CAMK_CAMKL_MARK_MARK2_ST	Q8TEW0	PARD3	Q7KZI7	MARK2	S1196	A1189V	1189	Missense	distal	-7	no	275.712	275.648	EPSD	TCGA	271.430	Down-regulation
CAMK_CAMKL_MARK_MARK2_ST	Q8TEW0	PARD3	Q7KZI7	MARK2	S1252	Q1251H	1251	Missense	proximal	-1	no	302.550	326.088	EPSD	TCGA;COSMIC	271.430	Up-regulation
CAMK_CAMKL_MARK_MARK2_ST	Q8TEW0	PARD3	Q7KZI7	MARK2	S1252	R1258W	1258	Missense	distal	6	no	302.550	289.773	EPSD	TCGA;COSMIC	271.430	Down-regulation
CAMK_CAMKL_MARK_MARK2_ST	Q8TEW0	PARD3	Q7KZI7	MARK2	S1252	S1245F	1245	Missense	distal	-7	no	302.550	302.653	EPSD	TCGA;COSMIC	271.430	Up-regulation
CAMK_CAMKL_MARK_MARK2_ST	Q8TEW0	PARD3	Q7KZI7	MARK2	S1337	A1340T	1340	Missense	distal	3	no	283.746	273.925	EPSD	TCGA;COSMIC	271.430	Down-regulation
CAMK_CAMKL_MARK_MARK2_ST	Q8TEW0	PARD3	Q7KZI7	MARK2	S1337	A1340V	1340	Missense	distal	3	no	283.746	315.415	EPSD	TCGA;COSMIC	271.430	Up-regulation
CAMK_CAMKL_MARK_MARK2_ST	Q8TEW0	PARD3	Q7KZI7	MARK2	S1337	P1334L	1334	Missense	distal	-3	no	283.746	319.218	EPSD	TCGA;COSMIC	271.430	Up-regulation
CAMK_CAMKL_MARK_MARK2_ST	Q8TEW0	PARD3	Q7KZI7	MARK2	S1337	P1334S	1334	Missense	distal	-3	no	283.746	284.604	EPSD	TCGA;COSMIC	271.430	Up-regulation
CAMK_CAMKL_MARK_MARK2_ST	Q8TEW0	PARD3	Q7KZI7	MARK2	T1347	A1340T	1340	Missense	distal	-7	no	286.323	286.275	EPSD	TCGA;COSMIC	271.430	Down-regulation
CAMK_CAMKL_MARK_MARK2_ST	Q8TEW0	PARD3	Q7KZI7	MARK2	T1347	A1340V	1340	Missense	distal	-7	no	286.323	286.259	EPSD	TCGA;COSMIC	271.430	Down-regulation
CAMK_CAMKL_MARK_MARK2_ST	Q8TEW0	PARD3	Q7KZI7	MARK2	T1347	P1353S	1353	Missense	distal	6	no	286.323	287.765	EPSD	TCGA;COSMIC	271.430	Up-regulation
CAMK_CAMKL_MARK_MARK2_ST	Q8TEW0	PARD3	Q7KZI7	MARK2	T1347	Q1346K	1346	Missense	proximal	-1	no	286.323	301.708	EPSD	TCGA;COSMIC	271.430	Up-regulation
CAMK_CAMKL_MARK_MARK2_ST	Q8TEW0	PARD3	Q7KZI7	MARK2	T1347	F1354S	1354	Missense	distal	7	no	286.323	284.211	EPSD	TCGA;COSMIC	271.430	Down-regulation
CAMK_CAMKL_MARK_MARK2_ST	Q8TEW0	PARD3	Q7KZI7	MARK2	T1347	L1345I	1345	Missense	proximal	-2	no	286.323	281.857	EPSD	TCGA	271.430	Down-regulation
CAMK_CAMKL_MARK_MARK2_ST	Q7KZI7	MARK2	Q7KZI7	MARK2	S30	R36W	36	Missense	distal	6	no	286.074	273.296	EPSD	TCGA;ICGC;COSMIC	271.430	Down-regulation
CAMK_CAMKL_MARK_MARK2_ST	Q7KZI7	MARK2	Q7KZI7	MARK2	S30	G37S	37	Missense	distal	7	no	286.074	286.289	EPSD	TCGA	271.430	Up-regulation
CAMK_CAMKL_MARK_MARK2_ST	Q7KZI7	MARK2	Q7KZI7	MARK2	S30	M34V	34	Missense	distal	4	no	286.074	323.435	EPSD	TCGA;ICGC;COSMIC	271.430	Up-regulation
CAMK_CAMKL_MARK_MARK2_ST	Q7KZI7	MARK2	Q7KZI7	MARK2	T58	I59T	59	Missense	proximal	1	no	331.237	323.987	EPSD	TCGA;ICGC;COSMIC	271.430	Down-regulation
CAMK_CAMKL_MARK_MARK2_ST	Q7KZI7	MARK2	Q7KZI7	MARK2	S93	R99C	99	Missense	distal	6	no	282.620	282.871	EPSD	TCGA;ICGC;COSMIC	271.430	Up-regulation
CAMK_CAMKL_MARK_MARK2_ST	Q7KZI7	MARK2	Q7KZI7	MARK2	S93	E100K	100	Missense	distal	7	no	282.620	295.443	EPSD	TCGA;ICGC;COSMIC	271.430	Up-regulation
CAMK_CAMKL_MARK_MARK2_ST	Q7KZI7	MARK2	Q7KZI7	MARK2	S93	K86N	86	Missense	distal	-7	no	282.620	282.591	EPSD	TCGA;ICGC;COSMIC	271.430	Down-regulation
CAMK_CAMKL_MARK_MARK2_ST	Q7KZI7	MARK2	Q7KZI7	MARK2	S274	R268C	268	Missense	distal	-6	no	357.007	356.959	EPSD	TCGA;ICGC;COSMIC	271.430	Down-regulation
CAMK_CAMKL_MARK_MARK2_ST	Q7KZI7	MARK2	Q7KZI7	MARK2	S274	Y272C	272	Missense	proximal	-2	no	357.007	361.673	EPSD	TCGA;ICGC	271.430	Up-regulation
CAMK_CAMKL_MARK_MARK2_ST	Q7KZI7	MARK2	Q7KZI7	MARK2	T275	R268C	268	Missense	distal	-7	no	351.104	351.123	EPSD	TCGA;ICGC;COSMIC	271.430	Up-regulation
CAMK_CAMKL_MARK_MARK2_ST	Q7KZI7	MARK2	Q7KZI7	MARK2	T275	Y272C	272	Missense	distal	-3	no	351.104	288.024	EPSD	TCGA;ICGC	271.430	Down-regulation
CAMK_CAMKL_MARK_MARK2_ST	Q7KZI7	MARK2	Q7KZI7	MARK2	S365	G370D	370	Missense	distal	5	no	277.431	293.997	EPSD	TCGA;COSMIC	271.430	Up-regulation
CAMK_CAMKL_MARK_MARK2_ST	Q7KZI7	MARK2	Q7KZI7	MARK2	S365	L361M	361	Missense	distal	-4	no	277.431	263.749	EPSD	TCGA;COSMIC	271.430	Loss
CAMK_CAMKL_MARK_MARK2_ST	Q7KZI7	MARK2	Q7KZI7	MARK2	S398	N402S	402	Missense	distal	4	no	272.534	185.436	EPSD	TCGA;ICGC;COSMIC	271.430	Loss
CAMK_CAMKL_MARK_MARK2_ST	Q7KZI7	MARK2	Q7KZI7	MARK2	S398	V399M	399	Missense	proximal	1	no	272.534	262.710	EPSD	TCGA;ICGC;COSMIC	271.430	Loss
CAMK_CAMKL_MARK_MARK2_ST	Q7KZI7	MARK2	Q7KZI7	MARK2	S400	N402S	402	Missense	proximal	2	no	345.504	356.585	PhosphoSitePlus	TCGA;ICGC;COSMIC	271.430	Up-regulation
CAMK_CAMKL_MARK_MARK2_ST	Q7KZI7	MARK2	Q7KZI7	MARK2	S400	V399M	399	Missense	proximal	-1	no	345.504	343.844	PhosphoSitePlus	TCGA;ICGC;COSMIC	271.430	Down-regulation
CAMK_CAMKL_MARK_MARK2_ST	Q7KZI7	MARK2	Q7KZI7	MARK2	S409	N402S	402	Missense	distal	-7	no	292.182	292.126	EPSD	TCGA;ICGC;COSMIC	271.430	Down-regulation
CAMK_CAMKL_MARK_MARK2_ST	Q7KZI7	MARK2	Q7KZI7	MARK2	S498	G495S	495	Missense	distal	-3	no	277.905	255.686	EPSD	TCGA;COSMIC	271.430	Loss
CAMK_CAMKL_MARK_MARK2_ST	Q7KZI7	MARK2	Q7KZI7	MARK2	S498	Q500H	500	Missense	proximal	2	no	277.905	280.352	EPSD	TCGA;COSMIC	271.430	Up-regulation
CAMK_CAMKL_MARK_MARK2_ST	Q7KZI7	MARK2	Q7KZI7	MARK2	S498	R491W	491	Missense	distal	-7	no	277.905	278.080	EPSD	TCGA;COSMIC	271.430	Up-regulation
CAMK_CAMKL_MARK_MARK2_ST	Q7KZI7	MARK2	Q7KZI7	MARK2	S517	S514Y	514	Missense	distal	-3	no	239.435	278.229	EPSD	TCGA;COSMIC	271.430	Gain
CAMK_CAMKL_MARK_MARK2_ST	Q7KZI7	MARK2	Q7KZI7	MARK2	S533	R528C	528	Missense	distal	-5	no	274.130	267.149	EPSD	TCGA;COSMIC	271.430	Loss
CAMK_CAMKL_MARK_MARK2_ST	Q7KZI7	MARK2	Q7KZI7	MARK2	S535	R528C	528	Missense	distal	-7	no	363.949	363.967	EPSD	TCGA;COSMIC	271.430	Up-regulation
CAMK_CAMKL_MARK_MARK2_ST	Q7KZI7	MARK2	Q7KZI7	MARK2	S535	N541Y	541	Missense	distal	6	no	363.949	354.486	EPSD	TCGA;COSMIC	271.430	Down-regulation
CAMK_CAMKL_MARK_MARK2_ST	Q7KZI7	MARK2	Q7KZI7	MARK2	S640	R644H	644	Missense	distal	4	no	286.099	326.902	EPSD	TCGA;COSMIC	271.430	Up-regulation
CAMK_CAMKL_MARK_MARK2_ST	Q7KZI7	MARK2	Q7KZI7	MARK2	S648	R644H	644	Missense	distal	-4	no	312.222	298.307	EPSD	TCGA;COSMIC	271.430	Down-regulation
CAMK_CAMKL_MARK_MARK2_ST	Q7KZI7	MARK2	Q7KZI7	MARK2	T667	P670L	670	Missense	distal	3	no	311.074	311.704	EPSD	TCGA;COSMIC	271.430	Up-regulation
CAMK_CAMKL_MARK_MARK2_ST	Q7KZI7	MARK2	Q7KZI7	MARK2	T667	T667M	667	Missense	central	0	yes	311.074	0.000	EPSD	TCGA;COSMIC	271.430	Loss
CAMK_CAMKL_MARK_MARK2_ST	Q92974	ARHGEF2	Q7KZI7	MARK2	S142	R139H	139	Missense	distal	-3	no	302.986	280.006	EPSD	TCGA;ICGC;COSMIC	271.430	Down-regulation
CAMK_CAMKL_MARK_MARK2_ST	Q92974	ARHGEF2	Q7KZI7	MARK2	S143	R139H	139	Missense	distal	-4	no	344.445	330.530	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	271.430	Down-regulation
CAMK_CAMKL_MARK_MARK2_ST	Q92974	ARHGEF2	Q7KZI7	MARK2	S163	R168C	168	Missense	distal	5	no	307.534	293.071	EPSD	TCGA;ICGC;COSMIC	271.430	Down-regulation
CAMK_CAMKL_MARK_MARK2_ST	Q92974	ARHGEF2	Q7KZI7	MARK2	S172	R168C	168	Missense	distal	-4	no	393.740	405.277	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	271.430	Up-regulation
CAMK_CAMKL_MARK_MARK2_ST	Q92974	ARHGEF2	Q7KZI7	MARK2	S172	S174F	174	Missense	proximal	2	no	393.740	361.566	EPSD;PhosphoSitePlus	TCGA;COSMIC;CCLE	271.430	Down-regulation
CAMK_CAMKL_MARK_MARK2_ST	Q92974	ARHGEF2	Q7KZI7	MARK2	S174	R168C	168	Missense	distal	-6	no	296.599	296.550	EPSD	TCGA;ICGC;COSMIC	271.430	Down-regulation
CAMK_CAMKL_MARK_MARK2_ST	Q92974	ARHGEF2	Q7KZI7	MARK2	S174	S174F	174	Missense	central	0	yes	296.599	0.000	EPSD	TCGA;COSMIC;CCLE	271.430	Loss
CAMK_CAMKL_MARK_MARK2_ST	Q92974	ARHGEF2	Q7KZI7	MARK2	T175	R168C	168	Missense	distal	-7	no	275.823	275.842	EPSD	TCGA;ICGC;COSMIC	271.430	Up-regulation
CAMK_CAMKL_MARK_MARK2_ST	Q92974	ARHGEF2	Q7KZI7	MARK2	T175	S174F	174	Missense	proximal	-1	no	275.823	274.347	EPSD	TCGA;COSMIC;CCLE	271.430	Down-regulation
CAMK_CAMKL_MARK_MARK2_ST	Q92974	ARHGEF2	Q7KZI7	MARK2	T184	R183Q	183	Missense	proximal	-1	no	303.591	285.175	EPSD	TCGA;COSMIC	271.430	Down-regulation
CAMK_CAMKL_MARK_MARK2_ST	Q92974	ARHGEF2	Q7KZI7	MARK2	T184	T184I	184	Missense	central	0	yes	303.591	0.000	EPSD	TCGA;COSMIC	271.430	Loss
CAMK_CAMKL_MARK_MARK2_ST	Q92974	ARHGEF2	Q7KZI7	MARK2	S186	R183Q	183	Missense	distal	-3	no	361.943	259.900	EPSD;PhosphoSitePlus	TCGA;COSMIC	271.430	Loss
CAMK_CAMKL_MARK_MARK2_ST	Q92974	ARHGEF2	Q7KZI7	MARK2	S186	T184I	184	Missense	proximal	-2	no	361.943	360.404	EPSD;PhosphoSitePlus	TCGA;COSMIC	271.430	Down-regulation
CAMK_CAMKL_MARK_MARK2_ST	Q92974	ARHGEF2	Q7KZI7	MARK2	T310	P307H	307	Missense	distal	-3	no	229.459	275.858	EPSD	TCGA;COSMIC	271.430	Gain
CAMK_CAMKL_MARK_MARK2_ST	Q92974	ARHGEF2	Q7KZI7	MARK2	T455	R452W	452	Missense	distal	-3	no	337.862	190.322	EPSD	TCGA;COSMIC	271.430	Loss
CAMK_CAMKL_MARK_MARK2_ST	Q92974	ARHGEF2	Q7KZI7	MARK2	T455	P456S	456	Missense	proximal	1	no	337.862	340.144	EPSD	TCGA;COSMIC	271.430	Up-regulation
CAMK_CAMKL_MARK_MARK2_ST	Q92974	ARHGEF2	Q7KZI7	MARK2	T455	P451T	451	Missense	distal	-4	no	337.862	326.584	EPSD	TCGA;COSMIC	271.430	Down-regulation
CAMK_CAMKL_MARK_MARK2_ST	Q92974	ARHGEF2	Q7KZI7	MARK2	S519	S522L	522	Missense	distal	3	no	272.266	294.970	EPSD	TCGA;COSMIC	271.430	Up-regulation
CAMK_CAMKL_MARK_MARK2_ST	Q92974	ARHGEF2	Q7KZI7	MARK2	S719	R724T	724	Missense	distal	5	no	272.879	270.401	EPSD	TCGA;COSMIC	271.430	Loss
CAMK_CAMKL_MARK_MARK2_ST	Q92974	ARHGEF2	Q7KZI7	MARK2	S782	R783W	783	Missense	proximal	1	no	276.770	266.697	EPSD	TCGA;COSMIC	271.430	Loss
CAMK_CAMKL_MARK_MARK2_ST	Q92974	ARHGEF2	Q7KZI7	MARK2	T802	P797S	797	Missense	distal	-5	no	282.521	282.964	EPSD	TCGA;COSMIC	271.430	Up-regulation
CAMK_CAMKL_MARK_MARK2_ST	Q92974	ARHGEF2	Q7KZI7	MARK2	T802	A805V	805	Missense	distal	3	no	282.521	314.190	EPSD	TCGA;COSMIC	271.430	Up-regulation
CAMK_CAMKL_MARK_MARK2_ST	Q92974	ARHGEF2	Q7KZI7	MARK2	S886	A889T	889	Missense	distal	3	no	361.187	351.366	EPSD	TCGA;COSMIC	271.430	Down-regulation
CAMK_CAMKL_MARK_MARK2_ST	Q92974	ARHGEF2	Q7KZI7	MARK2	S886	D891N	891	Missense	distal	5	no	361.187	368.080	EPSD	TCGA;COSMIC	271.430	Up-regulation
CAMK_CAMKL_MARK_MARK2_ST	Q92974	ARHGEF2	Q7KZI7	MARK2	S886	R885H	885	Missense	proximal	-1	no	361.187	366.309	EPSD	TCGA;COSMIC	271.430	Up-regulation
CAMK_CAMKL_MARK_MARK2_ST	Q92974	ARHGEF2	Q7KZI7	MARK2	S886	R883W	883	Missense	distal	-3	no	361.187	213.646	EPSD	TCGA;COSMIC	271.430	Loss
CAMK_CAMKL_MARK_MARK2_ST	Q92974	ARHGEF2	Q7KZI7	MARK2	S940	R936W	936	Missense	distal	-4	no	324.866	297.429	EPSD	TCGA;COSMIC	271.430	Down-regulation
CAMK_CAMKL_MARK_MARK2_ST	Q92974	ARHGEF2	Q7KZI7	MARK2	S940	P933L	933	Missense	distal	-7	no	324.866	324.849	EPSD	TCGA;COSMIC	271.430	Down-regulation
CAMK_CAMKL_MARK_MARK2_ST	Q92974	ARHGEF2	Q7KZI7	MARK2	S956	S960N	960	Missense	distal	4	no	188.971	276.070	EPSD	TCGA;COSMIC	271.430	Gain
CAMK_CAMKL_MARK_MARK2_ST	Q92974	ARHGEF2	Q7KZI7	MARK2	S960	R966T	966	Missense	distal	6	no	345.819	340.369	EPSD	TCGA;COSMIC	271.430	Down-regulation
CAMK_CAMKL_MARK_MARK2_ST	Q92974	ARHGEF2	Q7KZI7	MARK2	S960	S953R	953	Missense	distal	-7	no	345.819	345.842	EPSD	TCGA;COSMIC	271.430	Up-regulation
CAMK_CAMKL_MARK_MARK2_ST	Q92974	ARHGEF2	Q7KZI7	MARK2	S960	R954H	954	Missense	distal	-6	no	345.819	345.080	EPSD	TCGA;COSMIC	271.430	Down-regulation
CAMK_CAMKL_MARK_MARK2_ST	Q92974	ARHGEF2	Q7KZI7	MARK2	S960	R954C	954	Missense	distal	-6	no	345.819	345.770	EPSD	TCGA;COSMIC	271.430	Down-regulation
CAMK_CAMKL_MARK_MARK2_ST	Q92974	ARHGEF2	Q7KZI7	MARK2	S960	S960N	960	Missense	central	0	yes	345.819	0.000	EPSD	TCGA;COSMIC	271.430	Loss
CAMK_CAMKL_MARK_MARK2_ST	Q92974	ARHGEF2	Q7KZI7	MARK2	T965	S960N	960	Missense	distal	-5	no	255.330	275.336	EPSD	TCGA;COSMIC	271.430	Gain
CAMK_CAMKL_MARK_MARK2_ST	P10636	MAPT	Q7KZI7	MARK2	T17	D13N	13	Missense	distal	-4	no	321.150	323.011	EPSD	TCGA;ICGC;COSMIC	271.430	Up-regulation
CAMK_CAMKL_MARK_MARK2_ST	P10636	MAPT	Q7KZI7	MARK2	T17	R23S	23	Missense	distal	6	no	321.150	316.098	EPSD	TCGA;ICGC;COSMIC	271.430	Down-regulation
CAMK_CAMKL_MARK_MARK2_ST	P10636	MAPT	Q7KZI7	MARK2	T17	H14Y	14	Missense	distal	-3	no	321.150	314.403	EPSD	TCGA;ICGC;COSMIC	271.430	Down-regulation
CAMK_CAMKL_MARK_MARK2_ST	P10636	MAPT	Q7KZI7	MARK2	T17	G21W	21	Missense	distal	4	no	321.150	190.733	EPSD	TCGA;ICGC;COSMIC	271.430	Loss
CAMK_CAMKL_MARK_MARK2_ST	P10636	MAPT	Q7KZI7	MARK2	T17	K24I	24	Missense	distal	7	no	321.150	315.644	EPSD	TCGA;ICGC	271.430	Down-regulation
CAMK_CAMKL_MARK_MARK2_ST	P10636	MAPT	Q7KZI7	MARK2	S214	P212L	212	Missense	proximal	-2	no	313.338	316.149	EPSD	TCGA;ICGC;COSMIC	271.430	Up-regulation
CAMK_CAMKL_MARK_MARK2_ST	P10636	MAPT	Q7KZI7	MARK2	S214	E220K	220	Missense	distal	6	no	313.338	315.604	EPSD	TCGA;ICGC;COSMIC	271.430	Up-regulation
CAMK_CAMKL_MARK_MARK2_ST	P10636	MAPT	Q7KZI7	MARK2	T386	G387R	387	Missense	proximal	1	no	328.520	334.016	EPSD	TCGA;COSMIC	271.430	Up-regulation
CAMK_CAMKL_MARK_MARK2_ST	P10636	MAPT	Q7KZI7	MARK2	S388	G387R	387	Missense	proximal	-1	no	290.446	287.605	EPSD	TCGA;COSMIC	271.430	Down-regulation
CAMK_CAMKL_MARK_MARK2_ST	P10636	MAPT	Q7KZI7	MARK2	S451	E456K	456	Missense	distal	5	no	301.895	323.897	EPSD	TCGA;ICGC;COSMIC	271.430	Up-regulation
CAMK_CAMKL_MARK_MARK2_ST	P10636	MAPT	Q7KZI7	MARK2	S451	S452C	452	Missense	proximal	1	no	301.895	302.070	EPSD	TCGA;ICGC;COSMIC	271.430	Up-regulation
CAMK_CAMKL_MARK_MARK2_ST	P10636	MAPT	Q7KZI7	MARK2	S451	S444F	444	Missense	distal	-7	no	301.895	301.998	EPSD	TCGA;ICGC	271.430	Up-regulation
CAMK_CAMKL_MARK_MARK2_ST	P10636	MAPT	Q7KZI7	MARK2	S451	S452Y	452	Missense	proximal	1	no	301.895	301.106	EPSD	TCGA;ICGC;COSMIC	271.430	Down-regulation
CAMK_CAMKL_MARK_MARK2_ST	Q9NQT8	KIF13B	Q7KZI7	MARK2	T209	K206T	206	Missense	distal	-3	no	283.117	197.522	EPSD	TCGA;ICGC;COSMIC	271.430	Loss
CAMK_CAMKL_MARK_MARK2_ST	Q9NQT8	KIF13B	Q7KZI7	MARK2	T241	E244D	244	Missense	distal	3	no	238.261	273.788	EPSD	TCGA;ICGC;COSMIC	271.430	Gain
CAMK_CAMKL_MARK_MARK2_ST	Q9NQT8	KIF13B	Q7KZI7	MARK2	S250	A255V	255	Missense	distal	5	no	336.295	367.579	EPSD	TCGA	271.430	Up-regulation
CAMK_CAMKL_MARK_MARK2_ST	Q9NQT8	KIF13B	Q7KZI7	MARK2	S250	E244D	244	Missense	distal	-6	no	336.295	337.501	EPSD	TCGA;ICGC;COSMIC	271.430	Up-regulation
CAMK_CAMKL_MARK_MARK2_ST	Q9NQT8	KIF13B	Q7KZI7	MARK2	S250	K248T	248	Missense	proximal	-2	no	336.295	336.875	EPSD	TCGA;ICGC	271.430	Up-regulation
CAMK_CAMKL_MARK_MARK2_ST	Q9NQT8	KIF13B	Q7KZI7	MARK2	T329	M326L	326	Missense	distal	-3	no	217.343	283.397	EPSD	TCGA;ICGC;COSMIC	271.430	Gain
CAMK_CAMKL_MARK_MARK2_ST	Q9NQT8	KIF13B	Q7KZI7	MARK2	T513	Q508H	508	Missense	distal	-5	no	294.785	304.916	EPSD	TCGA;ICGC;COSMIC	271.430	Up-regulation
CAMK_CAMKL_MARK_MARK2_ST	Q9NQT8	KIF13B	Q7KZI7	MARK2	S1381	I1380M	1380	Missense	proximal	-1	no	362.657	358.801	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	271.430	Down-regulation
CAMK_CAMKL_MARK_MARK2_ST	Q9NQT8	KIF13B	Q7KZI7	MARK2	S1382	I1380M	1380	Missense	proximal	-2	no	295.086	296.644	EPSD	TCGA;ICGC;COSMIC	271.430	Up-regulation
CAMK_CAMKL_MARK_MARK2_ST	Q9NQT8	KIF13B	Q7KZI7	MARK2	S1398	N1404S	1404	Missense	distal	6	no	302.139	295.417	EPSD	TCGA;ICGC;COSMIC	271.430	Down-regulation
CAMK_CAMKL_MARK_MARK2_ST	Q9NQT8	KIF13B	Q7KZI7	MARK2	S1398	D1394Y	1394	Missense	distal	-4	no	302.139	292.382	EPSD	TCGA;ICGC	271.430	Down-regulation
CAMK_CAMKL_MARK_MARK2_ST	Q9NQT8	KIF13B	Q7KZI7	MARK2	S1410	N1404S	1404	Missense	distal	-6	no	349.208	347.780	PhosphoSitePlus;EPSD	TCGA;ICGC;COSMIC	271.430	Down-regulation
CAMK_CAMKL_MARK_MARK2_ST	Q9NQT8	KIF13B	Q7KZI7	MARK2	S1410	S1415Y	1415	Missense	distal	5	no	349.208	349.426	PhosphoSitePlus;EPSD	TCGA;ICGC;COSMIC	271.430	Up-regulation
CAMK_CAMKL_MARK_MARK2_ST	Q9NQT8	KIF13B	Q7KZI7	MARK2	T1418	I1423V	1423	Missense	distal	5	no	288.265	307.500	EPSD	TCGA;ICGC;COSMIC	271.430	Up-regulation
CAMK_CAMKL_MARK_MARK2_ST	Q9NQT8	KIF13B	Q7KZI7	MARK2	T1418	S1415Y	1415	Missense	distal	-3	no	288.265	327.058	EPSD	TCGA;ICGC;COSMIC	271.430	Up-regulation
CAMK_CAMKL_MARK_MARK2_ST	Q9NQT8	KIF13B	Q7KZI7	MARK2	S1438	D1440H	1440	Missense	proximal	2	no	333.142	304.030	EPSD	TCGA;ICGC;COSMIC	271.430	Down-regulation
CAMK_CAMKL_MARK_MARK2_ST	Q9NQT8	KIF13B	Q7KZI7	MARK2	S1449	P1453L	1453	Missense	distal	4	no	231.984	360.562	EPSD	TCGA;ICGC;COSMIC	271.430	Gain
CAMK_CAMKL_MARK_MARK2_ST	Q9NQT8	KIF13B	Q7KZI7	MARK2	S1449	P1453S	1453	Missense	distal	4	no	231.984	275.028	EPSD	TCGA;ICGC;COSMIC	271.430	Gain
CAMK_CAMKL_MARK_MARK2_ST	Q9NQT8	KIF13B	Q7KZI7	MARK2	S1481	E1474V	1474	Missense	distal	-7	no	298.714	298.660	EPSD	TCGA;ICGC;COSMIC	271.430	Down-regulation
CAMK_CAMKL_MARK_MARK2_ST	Q9NQT8	KIF13B	Q7KZI7	MARK2	S1481	R1479Q	1479	Missense	proximal	-2	no	298.714	297.304	EPSD	TCGA;ICGC;COSMIC	271.430	Down-regulation
CAMK_CAMKL_MARK_MARK2_ST	Q9NQT8	KIF13B	Q7KZI7	MARK2	S1537	V1544I	1544	Missense	distal	7	no	293.061	285.887	EPSD	TCGA;ICGC;COSMIC	271.430	Down-regulation
CAMK_CAMKL_MARK_MARK2_ST	Q9NQT8	KIF13B	Q7KZI7	MARK2	S1795	A1792T	1792	Missense	distal	-3	no	249.365	277.709	EPSD	TCGA;ICGC;COSMIC	271.430	Gain
CAMK_CAMKL_MARK_MARK2_ST	Q9NQT8	KIF13B	Q7KZI7	MARK2	S1797	A1792T	1792	Missense	distal	-5	no	315.929	322.057	EPSD	TCGA;ICGC;COSMIC	271.430	Up-regulation
CAMK_CAMKL_MARK_MARK2_ST	Q9NQT8	KIF13B	Q7KZI7	MARK2	S1797	S1803L	1803	Missense	distal	6	no	315.929	329.020	EPSD	TCGA;ICGC;COSMIC	271.430	Up-regulation
CAMK_CAMKL_MARK_MARK2_ST	Q7L804	RAB11FIP2	Q7KZI7	MARK2	S150	T148I	148	Missense	proximal	-2	no	287.118	285.579	EPSD	TCGA;ICGC;COSMIC	271.430	Down-regulation
CAMK_CAMKL_MARK_MARK2_ST	Q7L804	RAB11FIP2	Q7KZI7	MARK2	S150	S150C	150	Missense	central	0	yes	287.118	0.000	EPSD	TCGA;ICGC;COSMIC	271.430	Loss
CAMK_CAMKL_MARK_MARK2_ST	Q7L804	RAB11FIP2	Q7KZI7	MARK2	S150	A149T	149	Missense	proximal	-1	no	287.118	282.115	EPSD	TCGA;ICGC;COSMIC	271.430	Down-regulation
CAMK_CAMKL_MARK_MARK2_ST	Q7L804	RAB11FIP2	Q7KZI7	MARK2	S162	P163S	163	Missense	proximal	1	no	292.247	294.529	EPSD	TCGA;ICGC;COSMIC	271.430	Up-regulation
CAMK_CAMKL_MARK_MARK2_ST	Q7L804	RAB11FIP2	Q7KZI7	MARK2	S162	P163L	163	Missense	proximal	1	no	292.247	299.018	EPSD	TCGA;ICGC;COSMIC	271.430	Up-regulation
CAMK_CAMKL_MARK_MARK2_ST	Q7L804	RAB11FIP2	Q7KZI7	MARK2	S162	S162Y	162	Missense	central	0	yes	292.247	0.000	EPSD	TCGA;ICGC;COSMIC	271.430	Loss
CAMK_CAMKL_MARK_MARK2_ST	Q7L804	RAB11FIP2	Q7KZI7	MARK2	S227	S224L	224	Missense	distal	-3	no	390.699	425.313	PhosphoSitePlus	TCGA;ICGC;COSMIC	271.430	Up-regulation
CAMK_CAMKL_MARK_MARK2_ST	Q7L804	RAB11FIP2	Q7KZI7	MARK2	S238	L241Q	241	Missense	distal	3	no	280.824	257.142	EPSD	TCGA;ICGC;COSMIC	271.430	Loss
CAMK_CAMKL_MARK_MARK2_ST	Q7L804	RAB11FIP2	Q7KZI7	MARK2	T245	L241Q	241	Missense	distal	-4	no	281.416	277.891	EPSD	TCGA;ICGC;COSMIC	271.430	Down-regulation
CAMK_CAMKL_MARK_MARK2_ST	Q7L804	RAB11FIP2	Q7KZI7	MARK2	S288	E292K	292	Missense	distal	4	no	289.458	286.849	EPSD	TCGA;ICGC;COSMIC	271.430	Down-regulation
CAMK_CAMKL_MARK_MARK2_ST	Q7L804	RAB11FIP2	Q7KZI7	MARK2	S288	S281Y	281	Missense	distal	-7	no	289.458	289.515	EPSD	TCGA;ICGC;COSMIC	271.430	Up-regulation
CAMK_CAMKL_MARK_MARK2_ST	Q7L804	RAB11FIP2	Q7KZI7	MARK2	S380	G379E	379	Missense	proximal	-1	no	300.125	289.480	EPSD	TCGA;ICGC;COSMIC	271.430	Down-regulation
CAMK_CAMKL_MARK_MARK2_ST	Q7L804	RAB11FIP2	Q7KZI7	MARK2	S380	G378V	378	Missense	proximal	-2	no	300.125	300.710	EPSD	TCGA;ICGC;COSMIC	271.430	Up-regulation
CAMK_CAMKL_MARK_MARK2_ST	Q7L804	RAB11FIP2	Q7KZI7	MARK2	S380	G379V	379	Missense	proximal	-1	no	300.125	282.183	EPSD	TCGA;ICGC;COSMIC	271.430	Down-regulation
CAMK_CAMKL_MARK_MARK2_ST	Q7L804	RAB11FIP2	Q7KZI7	MARK2	S382	G379E	379	Missense	distal	-3	no	340.659	266.786	EPSD	TCGA;ICGC;COSMIC	271.430	Loss
CAMK_CAMKL_MARK_MARK2_ST	Q7L804	RAB11FIP2	Q7KZI7	MARK2	S382	G378V	378	Missense	distal	-4	no	340.659	329.548	EPSD	TCGA;ICGC;COSMIC	271.430	Down-regulation
CAMK_CAMKL_MARK_MARK2_ST	Q7L804	RAB11FIP2	Q7KZI7	MARK2	S382	G379V	379	Missense	distal	-3	no	340.659	319.297	EPSD	TCGA;ICGC;COSMIC	271.430	Down-regulation
CAMK_CAMKL_MARK_MARK2_ST	Q99689	FEZ1	Q7KZI7	MARK2	S58	E52K	52	Missense	distal	-6	no	369.095	369.918	PhosphoSitePlus	TCGA;ICGC;COSMIC	271.430	Up-regulation
CAMK_CAMKL_MARK_MARK2_ST	Q99689	FEZ1	Q7KZI7	MARK2	S58	V63I	63	Missense	distal	5	no	369.095	349.861	PhosphoSitePlus	TCGA;ICGC;COSMIC	271.430	Down-regulation
CAMK_CAMKL_MARK_MARK2_ST	Q99689	FEZ1	Q7KZI7	MARK2	S58	S55I	55	Missense	distal	-3	no	369.095	316.041	PhosphoSitePlus	TCGA;ICGC;COSMIC	271.430	Down-regulation
CAMK_CAMKL_MARK_MARK2_ST	Q99689	FEZ1	Q7KZI7	MARK2	S58	N64T	64	Missense	distal	6	no	369.095	361.976	PhosphoSitePlus	TCGA;ICGC;COSMIC	271.430	Down-regulation
CAMK_CAMKL_MARK_MARK2_ST	Q99689	FEZ1	Q7KZI7	MARK2	S58	L62I	62	Missense	distal	4	no	369.095	345.007	PhosphoSitePlus	TCGA;ICGC;COSMIC	271.430	Down-regulation
CAMK_CAMKL_MARK_MARK2_ST	Q99689	FEZ1	Q7KZI7	MARK2	S298	R303L	303	Missense	distal	5	no	280.634	286.416	EPSD	TCGA;ICGC;COSMIC	271.430	Up-regulation
CAMK_CAMKL_MARK_MARK2_ST	Q99689	FEZ1	Q7KZI7	MARK2	S298	R303Q	303	Missense	distal	5	no	280.634	271.234	EPSD	TCGA;ICGC;COSMIC	271.430	Loss
CAMK_CAMKL_MARK_MARK2_ST	Q99689	FEZ1	Q7KZI7	MARK2	S316	N322T	322	Missense	distal	6	no	292.063	284.943	EPSD	TCGA;ICGC;COSMIC	271.430	Down-regulation
CAMK_CAMKL_MARK_MARK2_ST	Q99689	FEZ1	Q7KZI7	MARK2	S316	R314H	314	Missense	proximal	-2	no	292.063	291.832	EPSD	TCGA	271.430	Down-regulation
CAMK_CAMKL_MARK_MARK2_ST	Q9H4P4	RNF41	Q7KZI7	MARK2	S254	N249D	249	Missense	distal	-5	no	357.404	345.652	PhosphoSitePlus	TCGA;ICGC;COSMIC	271.430	Down-regulation
CAMK_CAMKL_MARK_MARK2_ST	Q9H4P4	RNF41	Q7KZI7	MARK2	S254	H251Q	251	Missense	distal	-3	no	357.404	278.341	PhosphoSitePlus	TCGA;ICGC;COSMIC	271.430	Down-regulation
CAMK_CAMKL_MARK_MARK2_ST	Q9H4P4	RNF41	Q7KZI7	MARK2	S254	E252K	252	Missense	proximal	-2	no	357.404	356.718	PhosphoSitePlus	TCGA;ICGC	271.430	Down-regulation
CAMK_CAMKL_MARK_MARK2_ST	P78352	DLG4	Q7KZI7	MARK2	S478	D483Y	483	Missense	distal	5	no	325.676	327.968	EPSD	TCGA;ICGC;COSMIC	271.430	Up-regulation
CAMK_CAMKL_MARK_MARK2_ST	P78352	DLG4	Q7KZI7	MARK2	S480	D483Y	483	Missense	distal	3	no	339.005	283.707	EPSD	TCGA;ICGC;COSMIC	271.430	Down-regulation
CAMK_CAMKL_MARK_MARK2_ST	Q9UQB8	BAIAP2	Q7KZI7	MARK2	S259	A257V	257	Missense	proximal	-2	no	281.512	282.167	EPSD	TCGA;COSMIC	271.430	Up-regulation
CAMK_CAMKL_MARK_MARK2_ST	Q9UQB8	BAIAP2	Q7KZI7	MARK2	S259	P255L	255	Missense	distal	-4	no	281.512	268.470	EPSD	TCGA;COSMIC	271.430	Loss
CAMK_CAMKL_MARK_MARK2_ST	Q9UQB8	BAIAP2	Q7KZI7	MARK2	S259	L258R	258	Missense	proximal	-1	no	281.512	271.452	EPSD	TCGA;COSMIC	271.430	Down-regulation
CAMK_CAMKL_MARK_MARK2_ST	Q9UQB8	BAIAP2	Q7KZI7	MARK2	S261	A257V	257	Missense	distal	-4	no	297.356	301.922	EPSD	TCGA;COSMIC	271.430	Up-regulation
CAMK_CAMKL_MARK_MARK2_ST	Q9UQB8	BAIAP2	Q7KZI7	MARK2	S261	P255L	255	Missense	distal	-6	no	297.356	299.566	EPSD	TCGA;COSMIC	271.430	Up-regulation
CAMK_CAMKL_MARK_MARK2_ST	Q9UQB8	BAIAP2	Q7KZI7	MARK2	S261	L258R	258	Missense	distal	-3	no	297.356	331.263	EPSD	TCGA;COSMIC	271.430	Up-regulation
CAMK_CAMKL_MARK_MARK2_ST	Q9UQB8	BAIAP2	Q7KZI7	MARK2	T303	G301S	301	Missense	proximal	-2	no	293.838	296.361	EPSD	TCGA;COSMIC	271.430	Up-regulation
CAMK_CAMKL_MARK_MARK2_ST	Q9UQB8	BAIAP2	Q7KZI7	MARK2	S329	K322E	322	Missense	distal	-7	no	286.401	286.447	EPSD	TCGA;COSMIC	271.430	Up-regulation
CAMK_CAMKL_MARK_MARK2_ST	Q9UQB8	BAIAP2	Q7KZI7	MARK2	S329	S325P	325	Missense	distal	-4	no	286.401	292.648	EPSD	TCGA;COSMIC	271.430	Up-regulation
CAMK_CAMKL_MARK_MARK2_ST	Q9UQB8	BAIAP2	Q7KZI7	MARK2	S329	S336F	336	Missense	distal	7	no	286.401	288.514	EPSD	TCGA;COSMIC	271.430	Up-regulation
CAMK_CAMKL_MARK_MARK2_ST	Q9UQB8	BAIAP2	Q7KZI7	MARK2	S329	P327S	327	Missense	proximal	-2	no	286.401	288.329	EPSD	TCGA;COSMIC	271.430	Up-regulation
CAMK_CAMKL_MARK_MARK2_ST	Q9UQB8	BAIAP2	Q7KZI7	MARK2	S329	P327L	327	Missense	proximal	-2	no	286.401	289.213	EPSD	TCGA;COSMIC;GDSC	271.430	Up-regulation
CAMK_CAMKL_MARK_MARK2_ST	Q9UQB8	BAIAP2	Q7KZI7	MARK2	S329	S336P	336	Missense	distal	7	no	286.401	292.333	EPSD	TCGA;COSMIC	271.430	Up-regulation
CAMK_CAMKL_MARK_MARK2_ST	Q9UQB8	BAIAP2	Q7KZI7	MARK2	S336	P342L	342	Missense	distal	6	no	279.004	293.537	EPSD	TCGA;COSMIC	271.430	Up-regulation
CAMK_CAMKL_MARK_MARK2_ST	Q9UQB8	BAIAP2	Q7KZI7	MARK2	S336	S336F	336	Missense	central	0	yes	279.004	0.000	EPSD	TCGA;COSMIC	271.430	Loss
CAMK_CAMKL_MARK_MARK2_ST	Q9UQB8	BAIAP2	Q7KZI7	MARK2	S336	S336P	336	Missense	central	0	yes	279.004	0.000	EPSD	TCGA;COSMIC	271.430	Loss
CAMK_CAMKL_MARK_MARK2_ST	Q9UQB8	BAIAP2	Q7KZI7	MARK2	S338	P342L	342	Missense	distal	4	no	201.319	329.898	EPSD	TCGA;COSMIC	271.430	Gain
CAMK_CAMKL_MARK_MARK2_ST	Q9UQB8	BAIAP2	Q7KZI7	MARK2	T340	P342L	342	Missense	proximal	2	no	278.770	260.375	EPSD	TCGA;COSMIC	271.430	Loss
CAMK_CAMKL_MARK_MARK2_ST	Q9UQB8	BAIAP2	Q7KZI7	MARK2	T340	S336F	336	Missense	distal	-4	no	278.770	273.190	EPSD	TCGA;COSMIC	271.430	Down-regulation
CAMK_CAMKL_MARK_MARK2_ST	Q9UQB8	BAIAP2	Q7KZI7	MARK2	T340	S336P	336	Missense	distal	-4	no	278.770	285.017	EPSD	TCGA;COSMIC	271.430	Up-regulation
CAMK_CAMKL_MARK_MARK2_ST	Q9UQB8	BAIAP2	Q7KZI7	MARK2	S364	S366F	366	Missense	proximal	2	no	305.903	273.729	EPSD	TCGA;COSMIC	271.430	Down-regulation
CAMK_CAMKL_MARK_MARK2_ST	Q9UQB8	BAIAP2	Q7KZI7	MARK2	S364	L371P	371	Missense	distal	7	no	305.903	302.269	EPSD	TCGA;COSMIC	271.430	Down-regulation
CAMK_CAMKL_MARK_MARK2_ST	Q9UQB8	BAIAP2	Q7KZI7	MARK2	S366	S366F	366	Missense	central	0	yes	364.709	0.000	PhosphoSitePlus	TCGA;COSMIC	271.430	Loss
CAMK_CAMKL_MARK_MARK2_ST	Q9UQB8	BAIAP2	Q7KZI7	MARK2	S366	L371P	371	Missense	distal	5	no	364.709	350.669	PhosphoSitePlus	TCGA;COSMIC	271.430	Down-regulation
CAMK_CAMKL_MARK_MARK2_ST	Q9UQB8	BAIAP2	Q7KZI7	MARK2	S446	S446C	446	Missense	central	0	yes	285.033	0.000	EPSD	TCGA	271.430	Loss
CAMK_CAMKL_MARK_MARK2_ST	Q9UQB8	BAIAP2	Q7KZI7	MARK2	S446	K451E	451	Missense	distal	5	no	285.033	263.031	EPSD	TCGA;ICGC;COSMIC	271.430	Loss
CAMK_CAMKL_MARK_MARK2_ST	Q9UQB8	BAIAP2	Q7KZI7	MARK2	S454	K451E	451	Missense	distal	-3	no	365.819	253.294	EPSD	TCGA;ICGC;COSMIC	271.430	Loss
CAMK_CAMKL_MARK_MARK2_ST	Q9UQB8	BAIAP2	Q7KZI7	MARK2	S454	L459M	459	Missense	distal	5	no	365.819	354.218	EPSD	TCGA;ICGC	271.430	Down-regulation
CAMK_CAMKL_MARK_MARK2_ST	Q9UQB8	BAIAP2	Q7KZI7	MARK2	S509	D503H	503	Missense	distal	-6	no	315.421	313.163	EPSD	TCGA;ICGC;COSMIC	271.430	Down-regulation
CAMK_CAMKL_MARK_MARK2_ST	Q9BXM7	PINK1	Q7KZI7	MARK2	T313	R312W	312	Missense	proximal	-1	no	355.598	337.818	PhosphoSitePlus	TCGA;ICGC;COSMIC	271.430	Down-regulation
CAMK_CAMKL_MARK_MARK2_ST	P46939	UTRN	Q7KZI7	MARK2	S10	K3M	3	Missense	distal	-7	no	390.586	390.656	EPSD	TCGA;ICGC;COSMIC	271.430	Up-regulation
CAMK_CAMKL_MARK_MARK2_ST	P46939	UTRN	Q7KZI7	MARK2	S10	E17K	17	Missense	distal	7	no	390.586	403.409	EPSD	TCGA;ICGC;COSMIC	271.430	Up-regulation
CAMK_CAMKL_MARK_MARK2_ST	P46939	UTRN	Q7KZI7	MARK2	S10	S10I	10	Missense	central	0	yes	390.586	0.000	EPSD	TCGA;ICGC;COSMIC	271.430	Loss
CAMK_CAMKL_MARK_MARK2_ST	P46939	UTRN	Q7KZI7	MARK2	T300	S295I	295	Missense	distal	-5	no	270.753	280.361	EPSD	TCGA;ICGC	271.430	Gain
CAMK_CAMKL_MARK_MARK2_ST	P46939	UTRN	Q7KZI7	MARK2	S569	R571Q	571	Missense	proximal	2	no	280.902	263.601	EPSD	TCGA;ICGC;COSMIC	271.430	Loss
CAMK_CAMKL_MARK_MARK2_ST	P46939	UTRN	Q7KZI7	MARK2	S933	D939N	939	Missense	distal	6	no	296.215	301.032	EPSD	TCGA;ICGC;COSMIC	271.430	Up-regulation
CAMK_CAMKL_MARK_MARK2_ST	P46939	UTRN	Q7KZI7	MARK2	S1005	H1009R	1009	Missense	distal	4	no	310.427	269.624	EPSD	TCGA;ICGC;COSMIC	271.430	Loss
CAMK_CAMKL_MARK_MARK2_ST	P46939	UTRN	Q7KZI7	MARK2	S1005	D1007Y	1007	Missense	proximal	2	no	310.427	298.876	EPSD	TCGA;ICGC	271.430	Down-regulation
CAMK_CAMKL_MARK_MARK2_ST	P46939	UTRN	Q7KZI7	MARK2	S1258	K1257R	1257	Missense	proximal	-1	no	361.317	364.348	PhosphoSitePlus	TCGA;ICGC;COSMIC	271.430	Up-regulation
CAMK_CAMKL_MARK_MARK2_ST	P46939	UTRN	Q7KZI7	MARK2	T1361	R1367S	1367	Missense	distal	6	no	303.654	298.602	EPSD	TCGA;ICGC;COSMIC	271.430	Down-regulation
CAMK_CAMKL_MARK_MARK2_ST	P46939	UTRN	Q7KZI7	MARK2	T1361	L1364P	1364	Missense	distal	3	no	303.654	303.025	EPSD	TCGA;ICGC;COSMIC	271.430	Down-regulation
CAMK_CAMKL_MARK_MARK2_ST	P46939	UTRN	Q7KZI7	MARK2	S1486	L1485V	1485	Missense	proximal	-1	no	289.084	263.923	EPSD	TCGA;ICGC;COSMIC	271.430	Loss
CAMK_CAMKL_MARK_MARK2_ST	P46939	UTRN	Q7KZI7	MARK2	S1486	Y1482C	1482	Missense	distal	-4	no	289.084	308.562	EPSD	TCGA;ICGC;COSMIC	271.430	Up-regulation
CAMK_CAMKL_MARK_MARK2_ST	P46939	UTRN	Q7KZI7	MARK2	S1486	M1479V	1479	Missense	distal	-7	no	289.084	289.005	EPSD	TCGA;ICGC;COSMIC	271.430	Down-regulation
CAMK_CAMKL_MARK_MARK2_ST	P46939	UTRN	Q7KZI7	MARK2	S1486	E1491D	1491	Missense	distal	5	no	289.084	303.777	EPSD	TCGA;ICGC	271.430	Up-regulation
CAMK_CAMKL_MARK_MARK2_ST	P46939	UTRN	Q7KZI7	MARK2	S1695	R1692L	1692	Missense	distal	-3	no	306.864	272.957	EPSD	TCGA;ICGC;COSMIC	271.430	Down-regulation
CAMK_CAMKL_MARK_MARK2_ST	P46939	UTRN	Q7KZI7	MARK2	S1695	R1692C	1692	Missense	distal	-3	no	306.864	214.057	EPSD	TCGA;ICGC;GDSC	271.430	Loss
CAMK_CAMKL_MARK_MARK2_ST	P46939	UTRN	Q7KZI7	MARK2	S1746	I1744M	1744	Missense	proximal	-2	no	282.605	284.163	EPSD	TCGA;ICGC;COSMIC	271.430	Up-regulation
CAMK_CAMKL_MARK_MARK2_ST	P46939	UTRN	Q7KZI7	MARK2	S1795	V1789M	1789	Missense	distal	-6	no	293.587	292.589	EPSD	TCGA;ICGC;COSMIC	271.430	Down-regulation
CAMK_CAMKL_MARK_MARK2_ST	P46939	UTRN	Q7KZI7	MARK2	T2112	E2114K	2114	Missense	proximal	2	no	309.938	286.571	EPSD	TCGA;ICGC;COSMIC	271.430	Down-regulation
CAMK_CAMKL_MARK_MARK2_ST	P46939	UTRN	Q7KZI7	MARK2	S2211	Q2218K	2218	Missense	distal	7	no	324.528	345.273	EPSD	TCGA;ICGC;COSMIC	271.430	Up-regulation
CAMK_CAMKL_MARK_MARK2_ST	P46939	UTRN	Q7KZI7	MARK2	S2211	V2209L	2209	Missense	proximal	-2	no	324.528	327.351	EPSD	TCGA;ICGC	271.430	Up-regulation
CAMK_CAMKL_MARK_MARK2_ST	P46939	UTRN	Q7KZI7	MARK2	S2211	A2212V	2212	Missense	proximal	1	no	324.528	334.994	EPSD	TCGA;ICGC;COSMIC	271.430	Up-regulation
CAMK_CAMKL_MARK_MARK2_ST	P46939	UTRN	Q7KZI7	MARK2	S2226	S2223L	2223	Missense	distal	-3	no	265.109	299.723	EPSD	TCGA;ICGC;COSMIC;CCLE	271.430	Gain
CAMK_CAMKL_MARK_MARK2_ST	P46939	UTRN	Q7KZI7	MARK2	S2567	R2563K	2563	Missense	distal	-4	no	286.958	284.590	EPSD	TCGA;ICGC;COSMIC	271.430	Down-regulation
CAMK_CAMKL_MARK_MARK2_ST	P46939	UTRN	Q7KZI7	MARK2	S2644	N2641K	2641	Missense	distal	-3	no	289.259	321.174	EPSD	TCGA;ICGC;COSMIC	271.430	Up-regulation
CAMK_CAMKL_MARK_MARK2_ST	P46939	UTRN	Q7KZI7	MARK2	S2644	E2651K	2651	Missense	distal	7	no	289.259	302.082	EPSD	TCGA;ICGC;COSMIC	271.430	Up-regulation
CAMK_CAMKL_MARK_MARK2_ST	P46939	UTRN	Q7KZI7	MARK2	S2666	K2663N	2663	Missense	distal	-3	no	315.156	283.240	EPSD	TCGA;ICGC;COSMIC	271.430	Down-regulation
CAMK_CAMKL_MARK_MARK2_ST	P46939	UTRN	Q7KZI7	MARK2	S2760	L2755V	2755	Missense	distal	-5	no	284.984	291.888	EPSD	TCGA;ICGC;COSMIC	271.430	Up-regulation
CAMK_CAMKL_MARK_MARK2_ST	P46939	UTRN	Q7KZI7	MARK2	S2851	A2853S	2853	Missense	proximal	2	no	305.310	344.492	EPSD	TCGA	271.430	Up-regulation
CAMK_CAMKL_MARK_MARK2_ST	P46939	UTRN	Q7KZI7	MARK2	S2851	S2851F	2851	Missense	central	0	yes	305.310	0.000	EPSD	TCGA;ICGC;COSMIC	271.430	Loss
CAMK_CAMKL_MARK_MARK2_ST	P46939	UTRN	Q7KZI7	MARK2	S3309	S3312L	3312	Missense	distal	3	no	260.377	283.081	EPSD	TCGA;ICGC;COSMIC	271.430	Gain
CAMK_CAMKL_MARK_MARK2_ST	Q9UQL6	HDAC5	Q7KZI7	MARK2	S53	G52E	52	Missense	proximal	-1	no	296.102	285.456	EPSD	TCGA;ICGC;COSMIC	271.430	Down-regulation
CAMK_CAMKL_MARK_MARK2_ST	Q9UQL6	HDAC5	Q7KZI7	MARK2	S55	G52E	52	Missense	distal	-3	no	277.288	203.416	EPSD	TCGA;ICGC;COSMIC	271.430	Loss
CAMK_CAMKL_MARK_MARK2_ST	Q6WKZ4	RAB11FIP1	Q7KZI7	MARK2	S6	V5I	5	Missense	proximal	-1	no	302.469	304.666	EPSD	TCGA;ICGC	271.430	Up-regulation
CAMK_CAMKL_MARK_MARK2_ST	Q6WKZ4	RAB11FIP1	Q7KZI7	MARK2	S202	S199L	199	Missense	distal	-3	no	268.358	302.972	EPSD	TCGA;COSMIC	271.430	Gain
CAMK_CAMKL_MARK_MARK2_ST	Q6WKZ4	RAB11FIP1	Q7KZI7	MARK2	T219	K213N	213	Missense	distal	-6	no	280.278	280.634	EPSD	TCGA;COSMIC	271.430	Up-regulation
CAMK_CAMKL_MARK_MARK2_ST	Q6WKZ4	RAB11FIP1	Q7KZI7	MARK2	S268	D261G	261	Missense	distal	-7	no	282.540	282.671	EPSD	TCGA;COSMIC	271.430	Up-regulation
CAMK_CAMKL_MARK_MARK2_ST	Q6WKZ4	RAB11FIP1	Q7KZI7	MARK2	S307	R314L	314	Missense	distal	7	no	318.660	317.520	EPSD	TCGA;COSMIC	271.430	Down-regulation
CAMK_CAMKL_MARK_MARK2_ST	Q6WKZ4	RAB11FIP1	Q7KZI7	MARK2	S313	R314L	314	Missense	proximal	1	no	270.585	273.030	EPSD	TCGA;COSMIC	271.430	Gain
CAMK_CAMKL_MARK_MARK2_ST	Q6WKZ4	RAB11FIP1	Q7KZI7	MARK2	S315	R314L	314	Missense	proximal	-1	no	297.961	308.020	EPSD	TCGA;COSMIC	271.430	Up-regulation
CAMK_CAMKL_MARK_MARK2_ST	Q6WKZ4	RAB11FIP1	Q7KZI7	MARK2	S342	P346L	346	Missense	distal	4	no	151.720	280.298	EPSD	TCGA;COSMIC	271.430	Gain
CAMK_CAMKL_MARK_MARK2_ST	Q6WKZ4	RAB11FIP1	Q7KZI7	MARK2	S343	S345F	345	Missense	proximal	2	no	304.388	272.214	EPSD	TCGA;COSMIC	271.430	Down-regulation
CAMK_CAMKL_MARK_MARK2_ST	Q6WKZ4	RAB11FIP1	Q7KZI7	MARK2	S343	P346L	346	Missense	distal	3	no	304.388	305.017	EPSD	TCGA;COSMIC	271.430	Up-regulation
CAMK_CAMKL_MARK_MARK2_ST	Q6WKZ4	RAB11FIP1	Q7KZI7	MARK2	S356	E359Q	359	Missense	distal	3	no	297.849	283.547	EPSD	TCGA;COSMIC	271.430	Down-regulation
CAMK_CAMKL_MARK_MARK2_ST	Q6WKZ4	RAB11FIP1	Q7KZI7	MARK2	S356	A362V	362	Missense	distal	6	no	297.849	301.007	EPSD	TCGA;COSMIC;GDSC;CCLE	271.430	Up-regulation
CAMK_CAMKL_MARK_MARK2_ST	Q6WKZ4	RAB11FIP1	Q7KZI7	MARK2	S357	E359Q	359	Missense	proximal	2	no	341.221	322.227	EPSD	TCGA;COSMIC	271.430	Down-regulation
CAMK_CAMKL_MARK_MARK2_ST	Q6WKZ4	RAB11FIP1	Q7KZI7	MARK2	S357	A362V	362	Missense	distal	5	no	341.221	372.505	EPSD	TCGA;COSMIC;GDSC;CCLE	271.430	Up-regulation
CAMK_CAMKL_MARK_MARK2_ST	Q6WKZ4	RAB11FIP1	Q7KZI7	MARK2	S377	E383K	383	Missense	distal	6	no	285.422	287.688	EPSD	TCGA;COSMIC	271.430	Up-regulation
CAMK_CAMKL_MARK_MARK2_ST	Q6WKZ4	RAB11FIP1	Q7KZI7	MARK2	S382	E383K	383	Missense	proximal	1	no	291.698	286.704	EPSD	TCGA;COSMIC	271.430	Down-regulation
CAMK_CAMKL_MARK_MARK2_ST	Q6WKZ4	RAB11FIP1	Q7KZI7	MARK2	T386	E383K	383	Missense	distal	-3	no	195.553	308.078	EPSD	TCGA;COSMIC	271.430	Gain
CAMK_CAMKL_MARK_MARK2_ST	Q6WKZ4	RAB11FIP1	Q7KZI7	MARK2	S435	E430K	430	Missense	distal	-5	no	329.985	336.142	EPSD	TCGA;COSMIC	271.430	Up-regulation
CAMK_CAMKL_MARK_MARK2_ST	Q6WKZ4	RAB11FIP1	Q7KZI7	MARK2	S435	S435Y	435	Missense	central	0	yes	329.985	0.000	EPSD	TCGA	271.430	Loss
CAMK_CAMKL_MARK_MARK2_ST	Q6WKZ4	RAB11FIP1	Q7KZI7	MARK2	S625	P629L	629	Missense	distal	4	no	158.317	286.896	EPSD	TCGA;ICGC;COSMIC	271.430	Gain
CAMK_CAMKL_MARK_MARK2_ST	Q6WKZ4	RAB11FIP1	Q7KZI7	MARK2	S660	S660F	660	Missense	central	0	yes	305.734	0.000	EPSD	TCGA;ICGC;COSMIC	271.430	Loss
CAMK_CAMKL_MARK_MARK2_ST	Q6WKZ4	RAB11FIP1	Q7KZI7	MARK2	S719	Q714L	714	Missense	distal	-5	no	280.407	293.143	EPSD	TCGA;ICGC;COSMIC	271.430	Up-regulation
CAMK_CAMKL_MARK_MARK2_ST	Q6WKZ4	RAB11FIP1	Q7KZI7	MARK2	S733	P727S	727	Missense	distal	-6	no	275.763	276.422	EPSD	TCGA;ICGC	271.430	Up-regulation
CAMK_CAMKL_MARK_MARK2_ST	Q6WKZ4	RAB11FIP1	Q7KZI7	MARK2	S733	G736A	736	Missense	distal	3	no	275.763	284.560	EPSD	TCGA;ICGC;COSMIC	271.430	Up-regulation
CAMK_CAMKL_MARK_MARK2_ST	Q6WKZ4	RAB11FIP1	Q7KZI7	MARK2	S880	A877V	877	Missense	distal	-3	no	257.173	311.098	EPSD	TCGA;ICGC;COSMIC	271.430	Gain
CAMK_CAMKL_MARK_MARK2_ST	Q6WKZ4	RAB11FIP1	Q7KZI7	MARK2	S880	A882V	882	Missense	proximal	2	no	257.173	278.328	EPSD	TCGA;ICGC;COSMIC	271.430	Gain
CAMK_CAMKL_MARK_MARK2_ST	Q6WKZ4	RAB11FIP1	Q7KZI7	MARK2	S925	Q922R	922	Missense	distal	-3	no	170.971	273.014	EPSD	TCGA;ICGC;COSMIC	271.430	Gain
CAMK_CAMKL_MARK_MARK2_ST	Q6WKZ4	RAB11FIP1	Q7KZI7	MARK2	S958	P960H	960	Missense	proximal	2	no	314.151	293.898	EPSD	TCGA;ICGC;COSMIC	271.430	Down-regulation
CAMK_CAMKL_MARK_MARK2_ST	Q6WKZ4	RAB11FIP1	Q7KZI7	MARK2	T1274	K1278N	1278	Missense	distal	4	no	260.692	299.375	EPSD	TCGA;COSMIC	271.430	Gain
CMGC_CLK_CLK2_ST	O60829	PAGE4	P49760	CLK2	S7	R6I	6	Missense	proximal	-1	no	0.007	0.006	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	0.005	Down-regulation
CMGC_CLK_CLK2_ST	O60829	PAGE4	P49760	CLK2	S9	R6I	6	Missense	distal	-3	no	0.008	0.007	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	0.005	Down-regulation
CMGC_CLK_CLK2_ST	O60829	PAGE4	P49760	CLK2	T51	R57C	57	Missense	distal	6	no	0.007	0.006	EPSD;PhosphoSitePlus	TCGA;ICGC	0.005	Down-regulation
CMGC_CLK_CLK2_ST	O60829	PAGE4	P49760	CLK2	T71	K70N	70	Missense	proximal	-1	no	0.010	0.009	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	0.005	Down-regulation
CMGC_CLK_CLK2_ST	O60829	PAGE4	P49760	CLK2	S73	K70N	70	Missense	distal	-3	no	0.010	0.008	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	0.005	Down-regulation
CMGC_CLK_CLK2_ST	O60829	PAGE4	P49760	CLK2	S73	G78C	78	Missense	distal	5	no	0.010	0.009	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	0.005	Down-regulation
CMGC_CLK_CLK2_ST	O60829	PAGE4	P49760	CLK2	S73	R72Q	72	Missense	proximal	-1	no	0.010	0.009	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC;GDSC;CCLE	0.005	Down-regulation
CMGC_CLK_CLK2_ST	O60829	PAGE4	P49760	CLK2	S73	D67H	67	Missense	distal	-6	no	0.010	0.008	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	0.005	Down-regulation
CMGC_CLK_CLK2_ST	O60829	PAGE4	P49760	CLK2	S79	G78C	78	Missense	proximal	-1	no	0.008	0.007	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	0.005	Down-regulation
CMGC_CLK_CLK2_ST	P18031	PTPN1	P49760	CLK2	S50	D48Y	48	Missense	proximal	-2	no	0.006	0.004	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	0.005	Loss
CMGC_CLK_CLK2_ST	P18031	PTPN1	P49760	CLK2	S222	G220D	220	Missense	proximal	-2	no	0.004	0.005	EPSD	TCGA;COSMIC	0.005	Gain
CMGC_CLK_CLK2_ST	P18031	PTPN1	P49760	CLK2	S270	R268L	268	Missense	proximal	-2	no	0.006	0.005	EPSD	TCGA	0.005	Down-regulation
CMGC_CLK_CLK2_ST	P18031	PTPN1	P49760	CLK2	S295	S295F	295	Missense	central	0	yes	0.005	0.000	EPSD	TCGA;COSMIC	0.005	Loss
CMGC_CLK_CLK2_ST	P18031	PTPN1	P49760	CLK2	S363	A357T	357	Missense	distal	-6	no	0.005	0.003	EPSD	TCGA;COSMIC	0.005	Loss
CMGC_CLK_CLK2_ST	P18031	PTPN1	P49760	CLK2	S363	G360D	360	Missense	distal	-3	no	0.005	0.004	EPSD	TCGA;COSMIC	0.005	Loss
AGC_SGK_SGK1_ST	O00213	APBB1	O00141	SGK1	T92	R85H	85	Missense	distal	-7	no	9.998	10.292	EPSD	TCGA;ICGC;COSMIC	9.140	Up-regulation
AGC_SGK_SGK1_ST	O00213	APBB1	O00141	SGK1	T92	A96V	96	Missense	distal	4	no	9.998	9.689	EPSD	TCGA;ICGC;COSMIC	9.140	Down-regulation
AGC_SGK_SGK1_ST	O00213	APBB1	O00141	SGK1	T92	R89C	89	Missense	distal	-3	no	9.998	1.936	EPSD	TCGA;ICGC;COSMIC	9.140	Loss
AGC_SGK_SGK1_ST	O00213	APBB1	O00141	SGK1	S228	S233C	233	Missense	distal	5	no	9.831	9.800	EPSD	TCGA;ICGC;COSMIC	9.140	Down-regulation
AGC_SGK_SGK1_ST	O00213	APBB1	O00141	SGK1	S228	W224G	224	Missense	distal	-4	no	9.831	10.654	EPSD	TCGA;ICGC;COSMIC	9.140	Up-regulation
AGC_SGK_SGK1_ST	O00213	APBB1	O00141	SGK1	S228	S228F	228	Missense	central	0	yes	9.831	0.000	EPSD	TCGA;ICGC;COSMIC	9.140	Loss
AGC_SGK_SGK1_ST	O00213	APBB1	O00141	SGK1	S289	P288L	288	Missense	proximal	-1	no	10.163	10.266	EPSD	TCGA;COSMIC	9.140	Up-regulation
AGC_SGK_SGK1_ST	O00213	APBB1	O00141	SGK1	S289	G284V	284	Missense	distal	-5	no	10.163	6.405	EPSD	TCGA	9.140	Loss
AGC_SGK_SGK1_ST	O00213	APBB1	O00141	SGK1	S289	R285W	285	Missense	distal	-4	no	10.163	8.945	EPSD	TCGA;COSMIC	9.140	Loss
AGC_SGK_SGK1_ST	O00213	APBB1	O00141	SGK1	S289	P288S	288	Missense	proximal	-1	no	10.163	10.356	EPSD	TCGA;COSMIC	9.140	Up-regulation
AGC_SGK_SGK1_ST	O00213	APBB1	O00141	SGK1	S289	G284S	284	Missense	distal	-5	no	10.163	10.279	EPSD	TCGA;COSMIC	9.140	Up-regulation
AGC_SGK_SGK1_ST	O00213	APBB1	O00141	SGK1	S695	K701T	701	Missense	distal	6	no	9.621	9.469	EPSD	TCGA;COSMIC	9.140	Down-regulation
AGC_SGK_SGK1_ST	Q92597	NDRG1	O00141	SGK1	T328	R327C	327	Missense	proximal	-1	no	15.782	15.662	EPSD;PhosphoSitePlus	TCGA;COSMIC	9.140	Down-regulation
AGC_SGK_SGK1_ST	Q92597	NDRG1	O00141	SGK1	S330	S336C	336	Missense	distal	6	no	21.313	21.242	EPSD;PhosphoSitePlus	TCGA	9.140	Down-regulation
AGC_SGK_SGK1_ST	Q92597	NDRG1	O00141	SGK1	S330	R327C	327	Missense	distal	-3	no	21.313	13.251	EPSD;PhosphoSitePlus	TCGA;COSMIC	9.140	Down-regulation
AGC_SGK_SGK1_ST	Q92597	NDRG1	O00141	SGK1	S332	S336C	336	Missense	distal	4	no	15.370	15.340	EPSD	TCGA	9.140	Down-regulation
AGC_SGK_SGK1_ST	Q92597	NDRG1	O00141	SGK1	S332	R327C	327	Missense	distal	-5	no	15.370	9.108	EPSD	TCGA;COSMIC	9.140	Loss
AGC_SGK_SGK1_ST	Q92597	NDRG1	O00141	SGK1	S344	R343C	343	Missense	proximal	-1	no	14.488	14.368	EPSD	TCGA;COSMIC	9.140	Down-regulation
AGC_SGK_SGK1_ST	Q92597	NDRG1	O00141	SGK1	S344	T350P	350	Missense	distal	6	no	14.488	14.351	EPSD	TCGA;COSMIC	9.140	Down-regulation
AGC_SGK_SGK1_ST	Q92597	NDRG1	O00141	SGK1	S344	R341L	341	Missense	distal	-3	no	14.488	9.140	EPSD	TCGA;COSMIC	9.140	Down-regulation
AGC_SGK_SGK1_ST	Q92597	NDRG1	O00141	SGK1	S344	R343H	343	Missense	proximal	-1	no	14.488	14.376	EPSD	TCGA	9.140	Down-regulation
AGC_SGK_SGK1_ST	Q92597	NDRG1	O00141	SGK1	S344	R351Q	351	Missense	distal	7	no	14.488	14.689	EPSD	TCGA;COSMIC;CCLE	9.140	Up-regulation
AGC_SGK_SGK1_ST	Q92597	NDRG1	O00141	SGK1	T346	R343C	343	Missense	distal	-3	no	19.397	11.335	PhosphoSitePlus;EPSD	TCGA;COSMIC	9.140	Down-regulation
AGC_SGK_SGK1_ST	Q92597	NDRG1	O00141	SGK1	T346	T350P	350	Missense	distal	4	no	19.397	19.237	PhosphoSitePlus;EPSD	TCGA;COSMIC	9.140	Down-regulation
AGC_SGK_SGK1_ST	Q92597	NDRG1	O00141	SGK1	T346	R341L	341	Missense	distal	-5	no	19.397	15.169	PhosphoSitePlus;EPSD	TCGA;COSMIC	9.140	Down-regulation
AGC_SGK_SGK1_ST	Q92597	NDRG1	O00141	SGK1	T346	R343H	343	Missense	distal	-3	no	19.397	9.779	PhosphoSitePlus;EPSD	TCGA	9.140	Down-regulation
AGC_SGK_SGK1_ST	Q92597	NDRG1	O00141	SGK1	T346	R351Q	351	Missense	distal	5	no	19.397	19.368	PhosphoSitePlus;EPSD	TCGA;COSMIC;CCLE	9.140	Down-regulation
AGC_SGK_SGK1_ST	Q92597	NDRG1	O00141	SGK1	S354	T350P	350	Missense	distal	-4	no	16.892	16.408	EPSD	TCGA;COSMIC	9.140	Down-regulation
AGC_SGK_SGK1_ST	Q92597	NDRG1	O00141	SGK1	S354	E358K	358	Missense	distal	4	no	16.892	17.171	EPSD	TCGA;COSMIC	9.140	Up-regulation
AGC_SGK_SGK1_ST	Q92597	NDRG1	O00141	SGK1	S354	R351Q	351	Missense	distal	-3	no	16.892	6.230	EPSD	TCGA;COSMIC;CCLE	9.140	Loss
AGC_SGK_SGK1_ST	Q92597	NDRG1	O00141	SGK1	T356	T350P	350	Missense	distal	-6	no	17.543	17.360	EPSD;PhosphoSitePlus	TCGA;COSMIC	9.140	Down-regulation
AGC_SGK_SGK1_ST	Q92597	NDRG1	O00141	SGK1	T356	E358K	358	Missense	proximal	2	no	17.543	17.309	EPSD;PhosphoSitePlus	TCGA;COSMIC	9.140	Down-regulation
AGC_SGK_SGK1_ST	Q92597	NDRG1	O00141	SGK1	T356	R351Q	351	Missense	distal	-5	no	17.543	9.392	EPSD;PhosphoSitePlus	TCGA;COSMIC;CCLE	9.140	Down-regulation
AGC_SGK_SGK1_ST	Q92597	NDRG1	O00141	SGK1	T356	S362R	362	Missense	distal	6	no	17.543	17.485	EPSD;PhosphoSitePlus	TCGA;COSMIC	9.140	Down-regulation
AGC_SGK_SGK1_ST	Q92597	NDRG1	O00141	SGK1	S364	S367N	367	Missense	distal	3	no	15.470	15.342	EPSD	TCGA;COSMIC	9.140	Down-regulation
AGC_SGK_SGK1_ST	Q92597	NDRG1	O00141	SGK1	S364	E358K	358	Missense	distal	-6	no	15.470	15.765	EPSD	TCGA;COSMIC	9.140	Up-regulation
AGC_SGK_SGK1_ST	Q92597	NDRG1	O00141	SGK1	S364	S362R	362	Missense	proximal	-2	no	15.470	15.568	EPSD	TCGA;COSMIC	9.140	Up-regulation
AGC_SGK_SGK1_ST	Q92597	NDRG1	O00141	SGK1	T366	S367N	367	Missense	proximal	1	no	19.819	19.772	EPSD;PhosphoSitePlus	TCGA;COSMIC	9.140	Down-regulation
AGC_SGK_SGK1_ST	Q92597	NDRG1	O00141	SGK1	T366	S362R	362	Missense	distal	-4	no	19.819	19.513	EPSD;PhosphoSitePlus	TCGA;COSMIC	9.140	Down-regulation
AGC_SGK_SGK1_ST	Q92597	NDRG1	O00141	SGK1	S367	S362R	362	Missense	distal	-5	no	5.998	11.243	EPSD	TCGA;COSMIC	9.140	Gain
AGC_SGK_SGK1_ST	Q92597	NDRG1	O00141	SGK1	S389	G386R	386	Missense	distal	-3	no	6.743	13.299	EPSD	TCGA;COSMIC	9.140	Gain
AGC_SGK_SGK1_ST	Q96PU5	NEDD4L	O00141	SGK1	S256	R253W	253	Missense	distal	-3	no	12.531	2.836	EPSD	TCGA;ICGC;COSMIC	9.140	Loss
AGC_SGK_SGK1_ST	Q96PU5	NEDD4L	O00141	SGK1	S256	S256G	256	Missense	central	0	yes	12.531	0.000	EPSD	TCGA;ICGC;COSMIC	9.140	Loss
AGC_SGK_SGK1_ST	Q96PU5	NEDD4L	O00141	SGK1	T318	R314M	314	Missense	distal	-4	no	12.455	11.845	EPSD	TCGA;COSMIC	9.140	Down-regulation
AGC_SGK_SGK1_ST	Q96PU5	NEDD4L	O00141	SGK1	T318	L315F	315	Missense	distal	-3	no	12.455	7.680	EPSD	TCGA;ICGC;COSMIC	9.140	Loss
AGC_SGK_SGK1_ST	Q96PU5	NEDD4L	O00141	SGK1	S340	L338W	338	Missense	proximal	-2	no	16.090	15.546	EPSD	TCGA;COSMIC	9.140	Down-regulation
AGC_SGK_SGK1_ST	Q96PU5	NEDD4L	O00141	SGK1	S342	L338W	338	Missense	distal	-4	no	16.913	16.109	PhosphoSitePlus;EPSD	TCGA;COSMIC	9.140	Down-regulation
AGC_SGK_SGK1_ST	Q96PU5	NEDD4L	O00141	SGK1	S365	R364H	364	Missense	proximal	-1	no	10.437	10.325	EPSD	TCGA;COSMIC	9.140	Down-regulation
AGC_SGK_SGK1_ST	Q96PU5	NEDD4L	O00141	SGK1	S365	R364C	364	Missense	proximal	-1	no	10.437	10.317	EPSD	TCGA;COSMIC	9.140	Down-regulation
AGC_SGK_SGK1_ST	Q96PU5	NEDD4L	O00141	SGK1	S365	T369M	369	Missense	distal	4	no	10.437	10.312	EPSD	TCGA;COSMIC;GDSC;CCLE	9.140	Down-regulation
AGC_SGK_SGK1_ST	Q96PU5	NEDD4L	O00141	SGK1	T367	R364H	364	Missense	distal	-3	no	14.642	5.024	EPSD;PhosphoSitePlus	TCGA;COSMIC	9.140	Loss
AGC_SGK_SGK1_ST	Q96PU5	NEDD4L	O00141	SGK1	T367	R364C	364	Missense	distal	-3	no	14.642	6.580	EPSD;PhosphoSitePlus	TCGA;COSMIC	9.140	Loss
AGC_SGK_SGK1_ST	Q96PU5	NEDD4L	O00141	SGK1	T367	T369M	369	Missense	proximal	2	no	14.642	14.762	EPSD;PhosphoSitePlus	TCGA;COSMIC;GDSC;CCLE	9.140	Up-regulation
AGC_SGK_SGK1_ST	Q96PU5	NEDD4L	O00141	SGK1	S446	R442C	442	Missense	distal	-4	no	10.603	10.416	EPSD	TCGA;COSMIC	9.140	Down-regulation
AGC_SGK_SGK1_ST	Q96PU5	NEDD4L	O00141	SGK1	S446	R443Q	443	Missense	distal	-3	no	10.603	-0.059	EPSD	TCGA;COSMIC	9.140	Loss
AGC_SGK_SGK1_ST	Q96PU5	NEDD4L	O00141	SGK1	S446	R443W	443	Missense	distal	-3	no	10.603	0.908	EPSD	TCGA	9.140	Loss
AGC_SGK_SGK1_ST	Q96PU5	NEDD4L	O00141	SGK1	S446	R445C	445	Missense	proximal	-1	no	10.603	10.483	EPSD	TCGA;COSMIC	9.140	Down-regulation
AGC_SGK_SGK1_ST	Q96PU5	NEDD4L	O00141	SGK1	S448	L454V	454	Missense	distal	6	no	16.907	16.722	EPSD;PhosphoSitePlus	TCGA	9.140	Down-regulation
AGC_SGK_SGK1_ST	Q96PU5	NEDD4L	O00141	SGK1	S448	R442C	442	Missense	distal	-6	no	16.907	16.841	EPSD;PhosphoSitePlus	TCGA;COSMIC	9.140	Down-regulation
AGC_SGK_SGK1_ST	Q96PU5	NEDD4L	O00141	SGK1	S448	R443Q	443	Missense	distal	-5	no	16.907	8.756	EPSD;PhosphoSitePlus	TCGA;COSMIC	9.140	Loss
AGC_SGK_SGK1_ST	Q96PU5	NEDD4L	O00141	SGK1	S448	R443W	443	Missense	distal	-5	no	16.907	9.249	EPSD;PhosphoSitePlus	TCGA	9.140	Down-regulation
AGC_SGK_SGK1_ST	Q96PU5	NEDD4L	O00141	SGK1	S448	R445C	445	Missense	distal	-3	no	16.907	8.845	EPSD;PhosphoSitePlus	TCGA;COSMIC	9.140	Loss
AGC_SGK_SGK1_ST	Q96PU5	NEDD4L	O00141	SGK1	T473	R467H	467	Missense	distal	-6	no	9.493	9.412	EPSD	TCGA;COSMIC	9.140	Down-regulation
AGC_SGK_SGK1_ST	Q96PU5	NEDD4L	O00141	SGK1	T473	R468W	468	Missense	distal	-5	no	9.493	1.836	EPSD	TCGA;COSMIC	9.140	Loss
AGC_SGK_SGK1_ST	Q96PU5	NEDD4L	O00141	SGK1	T473	R467C	467	Missense	distal	-6	no	9.493	9.428	EPSD	TCGA;COSMIC	9.140	Down-regulation
AGC_SGK_SGK1_ST	Q96PU5	NEDD4L	O00141	SGK1	T473	S479P	479	Missense	distal	6	no	9.493	9.292	EPSD	TCGA	9.140	Down-regulation
AGC_SGK_SGK1_ST	Q96PU5	NEDD4L	O00141	SGK1	S637	R633W	633	Missense	distal	-4	no	11.349	10.131	EPSD	TCGA;COSMIC	9.140	Down-regulation
AGC_SGK_SGK1_ST	Q96PU5	NEDD4L	O00141	SGK1	S637	R633Q	633	Missense	distal	-4	no	11.349	10.887	EPSD	TCGA;COSMIC	9.140	Down-regulation
AGC_SGK_SGK1_ST	Q96PU5	NEDD4L	O00141	SGK1	S637	K639Q	639	Missense	proximal	2	no	11.349	11.575	EPSD	TCGA;COSMIC	9.140	Up-regulation
AGC_SGK_SGK1_ST	P49815	TSC2	O00141	SGK1	S188	K185R	185	Missense	distal	-3	no	4.921	11.007	EPSD	TCGA;ICGC	9.140	Gain
AGC_SGK_SGK1_ST	P49815	TSC2	O00141	SGK1	S311	S311F	311	Missense	central	0	yes	13.397	0.000	EPSD	TCGA;ICGC;COSMIC	9.140	Loss
AGC_SGK_SGK1_ST	P49815	TSC2	O00141	SGK1	S540	R537H	537	Missense	distal	-3	no	9.702	0.084	EPSD	TCGA;ICGC;COSMIC	9.140	Loss
AGC_SGK_SGK1_ST	P49815	TSC2	O00141	SGK1	S660	K657R	657	Missense	distal	-3	no	6.302	12.388	EPSD	TCGA;ICGC;COSMIC	9.140	Gain
AGC_SGK_SGK1_ST	P49815	TSC2	O00141	SGK1	S939	R943K	943	Missense	distal	4	no	14.517	14.748	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	9.140	Up-regulation
AGC_SGK_SGK1_ST	P49815	TSC2	O00141	SGK1	S939	R934S	934	Missense	distal	-5	no	14.517	9.272	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	9.140	Down-regulation
AGC_SGK_SGK1_ST	P49815	TSC2	O00141	SGK1	S979	R978H	978	Missense	proximal	-1	no	11.403	11.291	EPSD	TCGA;ICGC;COSMIC	9.140	Down-regulation
AGC_SGK_SGK1_ST	P49815	TSC2	O00141	SGK1	S981	R978H	978	Missense	distal	-3	no	15.889	6.270	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	9.140	Loss
AGC_SGK_SGK1_ST	P49815	TSC2	O00141	SGK1	S983	R978H	978	Missense	distal	-5	no	11.799	4.467	EPSD	TCGA;ICGC;COSMIC	9.140	Loss
AGC_SGK_SGK1_ST	P49815	TSC2	O00141	SGK1	S1014	D1013N	1013	Missense	proximal	-1	no	9.087	9.179	EPSD	TCGA	9.140	Gain
AGC_SGK_SGK1_ST	P49815	TSC2	O00141	SGK1	S1130	L1137F	1137	Missense	distal	7	no	18.186	18.529	EPSD;PhosphoSitePlus	TCGA;COSMIC	9.140	Up-regulation
AGC_SGK_SGK1_ST	P49815	TSC2	O00141	SGK1	S1130	R1127Q	1127	Missense	distal	-3	no	18.186	7.524	EPSD;PhosphoSitePlus	TCGA	9.140	Loss
AGC_SGK_SGK1_ST	P49815	TSC2	O00141	SGK1	S1132	L1137F	1137	Missense	distal	5	no	18.303	18.221	EPSD;PhosphoSitePlus	TCGA;COSMIC	9.140	Down-regulation
AGC_SGK_SGK1_ST	P49815	TSC2	O00141	SGK1	S1132	R1127Q	1127	Missense	distal	-5	no	18.303	10.152	EPSD;PhosphoSitePlus	TCGA	9.140	Down-regulation
AGC_SGK_SGK1_ST	P49815	TSC2	O00141	SGK1	T1271	R1268C	1268	Missense	distal	-3	no	15.277	7.215	EPSD	TCGA;COSMIC;CCLE	9.140	Loss
AGC_SGK_SGK1_ST	P49815	TSC2	O00141	SGK1	T1271	P1264L	1264	Missense	distal	-7	no	15.277	15.031	EPSD	TCGA;COSMIC	9.140	Down-regulation
AGC_SGK_SGK1_ST	P49815	TSC2	O00141	SGK1	T1271	P1265H	1265	Missense	distal	-6	no	15.277	15.421	EPSD	TCGA	9.140	Up-regulation
AGC_SGK_SGK1_ST	P49815	TSC2	O00141	SGK1	S1338	S1341N	1341	Missense	distal	3	no	13.956	13.827	EPSD	TCGA;COSMIC	9.140	Down-regulation
AGC_SGK_SGK1_ST	P49815	TSC2	O00141	SGK1	S1340	E1343D	1343	Missense	distal	3	no	12.632	12.720	EPSD	TCGA	9.140	Up-regulation
AGC_SGK_SGK1_ST	P49815	TSC2	O00141	SGK1	S1340	S1341N	1341	Missense	proximal	1	no	12.632	12.586	EPSD	TCGA;COSMIC	9.140	Down-regulation
AGC_SGK_SGK1_ST	P49815	TSC2	O00141	SGK1	S1364	E1360K	1360	Missense	distal	-4	no	10.900	11.451	EPSD	TCGA	9.140	Up-regulation
AGC_SGK_SGK1_ST	P49815	TSC2	O00141	SGK1	S1437	S1431L	1431	Missense	distal	-6	no	10.740	10.554	EPSD	TCGA;COSMIC	9.140	Down-regulation
AGC_SGK_SGK1_ST	P49815	TSC2	O00141	SGK1	S1437	R1438Q	1438	Missense	proximal	1	no	10.740	10.778	EPSD	TCGA;COSMIC	9.140	Up-regulation
AGC_SGK_SGK1_ST	P49815	TSC2	O00141	SGK1	S1454	S1449C	1449	Missense	distal	-5	no	10.461	9.444	EPSD	TCGA;COSMIC	9.140	Down-regulation
AGC_SGK_SGK1_ST	P49815	TSC2	O00141	SGK1	S1454	R1457Q	1457	Missense	distal	3	no	10.461	10.337	EPSD	TCGA;COSMIC	9.140	Down-regulation
AGC_SGK_SGK1_ST	P49815	TSC2	O00141	SGK1	S1454	R1451C	1451	Missense	distal	-3	no	10.461	2.399	EPSD	TCGA;COSMIC	9.140	Loss
AGC_SGK_SGK1_ST	P49815	TSC2	O00141	SGK1	T1462	S1466L	1466	Missense	distal	4	no	18.725	18.583	PhosphoSitePlus;EPSD	TCGA	9.140	Down-regulation
AGC_SGK_SGK1_ST	P49815	TSC2	O00141	SGK1	T1462	R1457Q	1457	Missense	distal	-5	no	18.725	10.574	PhosphoSitePlus;EPSD	TCGA;COSMIC	9.140	Down-regulation
AGC_SGK_SGK1_ST	P49815	TSC2	O00141	SGK1	S1464	S1466L	1466	Missense	proximal	2	no	12.564	12.852	EPSD	TCGA	9.140	Up-regulation
AGC_SGK_SGK1_ST	P49815	TSC2	O00141	SGK1	S1464	R1457Q	1457	Missense	distal	-7	no	12.564	13.093	EPSD	TCGA;COSMIC	9.140	Up-regulation
AGC_SGK_SGK1_ST	P49815	TSC2	O00141	SGK1	S1798	E1805K	1805	Missense	distal	7	no	18.412	17.994	EPSD;PhosphoSitePlus	TCGA;COSMIC	9.140	Down-regulation
AGC_SGK_SGK1_ST	P49815	TSC2	O00141	SGK1	S1798	S1798C	1798	Missense	central	0	yes	18.412	0.000	EPSD;PhosphoSitePlus	TCGA;COSMIC	9.140	Loss
AGC_SGK_SGK1_ST	P49815	TSC2	O00141	SGK1	S1798	S1798F	1798	Missense	central	0	yes	18.412	0.000	EPSD;PhosphoSitePlus	TCGA;COSMIC	9.140	Loss
AGC_SGK_SGK1_ST	O60343	TBC1D4	O00141	SGK1	S66	E61K	61	Missense	distal	-5	no	8.650	12.181	EPSD	TCGA;ICGC;COSMIC	9.140	Gain
AGC_SGK_SGK1_ST	O60343	TBC1D4	O00141	SGK1	S133	S133I	133	Missense	central	0	yes	9.772	0.000	EPSD	TCGA;ICGC;COSMIC	9.140	Loss
AGC_SGK_SGK1_ST	O60343	TBC1D4	O00141	SGK1	S304	D303Y	303	Missense	proximal	-1	no	13.809	13.834	EPSD	TCGA;ICGC;COSMIC	9.140	Up-regulation
AGC_SGK_SGK1_ST	O60343	TBC1D4	O00141	SGK1	S318	R315W	315	Missense	distal	-3	no	18.274	8.579	PhosphoSitePlus;EPSD	TCGA;COSMIC	9.140	Loss
AGC_SGK_SGK1_ST	O60343	TBC1D4	O00141	SGK1	S318	R315Q	315	Missense	distal	-3	no	18.274	7.612	PhosphoSitePlus;EPSD	TCGA;ICGC;COSMIC	9.140	Loss
AGC_SGK_SGK1_ST	O60343	TBC1D4	O00141	SGK1	S341	A342T	342	Missense	proximal	1	no	18.973	19.045	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	9.140	Up-regulation
AGC_SGK_SGK1_ST	O60343	TBC1D4	O00141	SGK1	S341	R336Q	336	Missense	distal	-5	no	18.973	10.822	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC;CCLE	9.140	Down-regulation
AGC_SGK_SGK1_ST	O60343	TBC1D4	O00141	SGK1	S485	L487V	487	Missense	proximal	2	no	9.074	9.187	EPSD	TCGA;ICGC;COSMIC	9.140	Gain
AGC_SGK_SGK1_ST	O60343	TBC1D4	O00141	SGK1	T568	F575L	575	Missense	distal	7	no	14.705	14.363	EPSD;PhosphoSitePlus	TCGA;ICGC;CCLE	9.140	Down-regulation
AGC_SGK_SGK1_ST	O60343	TBC1D4	O00141	SGK1	S570	F575L	575	Missense	distal	5	no	11.123	11.205	EPSD;PhosphoSitePlus	TCGA;ICGC;CCLE	9.140	Up-regulation
AGC_SGK_SGK1_ST	O60343	TBC1D4	O00141	SGK1	S570	R577K	577	Missense	distal	7	no	11.123	10.964	EPSD;PhosphoSitePlus	TCGA	9.140	Down-regulation
AGC_SGK_SGK1_ST	O60343	TBC1D4	O00141	SGK1	S588	R594W	594	Missense	distal	6	no	17.590	17.329	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	9.140	Down-regulation
AGC_SGK_SGK1_ST	O60343	TBC1D4	O00141	SGK1	S588	R585W	585	Missense	distal	-3	no	17.590	7.895	EPSD;PhosphoSitePlus	TCGA;ICGC	9.140	Loss
AGC_SGK_SGK1_ST	O60343	TBC1D4	O00141	SGK1	S666	R665C	665	Missense	proximal	-1	no	10.493	10.373	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	9.140	Down-regulation
AGC_SGK_SGK1_ST	O60343	TBC1D4	O00141	SGK1	S666	R660S	660	Missense	distal	-6	no	10.493	10.535	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	9.140	Up-regulation
AGC_SGK_SGK1_ST	O60343	TBC1D4	O00141	SGK1	S666	G659R	659	Missense	distal	-7	no	10.493	9.606	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	9.140	Down-regulation
AGC_SGK_SGK1_ST	O60343	TBC1D4	O00141	SGK1	S666	G659E	659	Missense	distal	-7	no	10.493	10.340	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	9.140	Down-regulation
AGC_SGK_SGK1_ST	O60343	TBC1D4	O00141	SGK1	S673	C677R	677	Missense	distal	4	no	14.070	14.036	EPSD	TCGA;ICGC	9.140	Down-regulation
AGC_SGK_SGK1_ST	O60343	TBC1D4	O00141	SGK1	T701	S704F	704	Missense	distal	3	no	9.540	8.733	EPSD	TCGA;ICGC;COSMIC	9.140	Loss
AGC_SGK_SGK1_ST	O60343	TBC1D4	O00141	SGK1	T701	A705T	705	Missense	distal	4	no	9.540	9.479	EPSD	TCGA;ICGC;COSMIC	9.140	Down-regulation
AGC_SGK_SGK1_ST	O60343	TBC1D4	O00141	SGK1	T701	F703L	703	Missense	proximal	2	no	9.540	9.212	EPSD	TCGA;ICGC	9.140	Down-regulation
AGC_SGK_SGK1_ST	O60343	TBC1D4	O00141	SGK1	S704	S704F	704	Missense	central	0	yes	12.441	0.000	EPSD	TCGA;ICGC;COSMIC	9.140	Loss
AGC_SGK_SGK1_ST	O60343	TBC1D4	O00141	SGK1	S704	A705T	705	Missense	proximal	1	no	12.441	12.513	EPSD	TCGA;ICGC;COSMIC	9.140	Up-regulation
AGC_SGK_SGK1_ST	O60343	TBC1D4	O00141	SGK1	S704	P711S	711	Missense	distal	7	no	12.441	12.049	EPSD	TCGA;ICGC;COSMIC	9.140	Down-regulation
AGC_SGK_SGK1_ST	O60343	TBC1D4	O00141	SGK1	S704	F703L	703	Missense	proximal	-1	no	12.441	12.661	EPSD	TCGA;ICGC	9.140	Up-regulation
AGC_SGK_SGK1_ST	O60343	TBC1D4	O00141	SGK1	T749	K747E	747	Missense	proximal	-2	no	12.979	12.681	EPSD	TCGA;COSMIC	9.140	Down-regulation
AGC_SGK_SGK1_ST	O60343	TBC1D4	O00141	SGK1	T749	G743E	743	Missense	distal	-6	no	12.979	12.996	EPSD	TCGA	9.140	Up-regulation
AGC_SGK_SGK1_ST	O60343	TBC1D4	O00141	SGK1	T749	R748S	748	Missense	proximal	-1	no	12.979	12.955	EPSD	TCGA;COSMIC	9.140	Down-regulation
AGC_SGK_SGK1_ST	O60343	TBC1D4	O00141	SGK1	T749	R748M	748	Missense	proximal	-1	no	12.979	12.808	EPSD	TCGA;COSMIC	9.140	Down-regulation
AGC_SGK_SGK1_ST	O60343	TBC1D4	O00141	SGK1	S751	K747E	747	Missense	distal	-4	no	20.327	19.777	EPSD;PhosphoSitePlus	TCGA;COSMIC	9.140	Down-regulation
AGC_SGK_SGK1_ST	O60343	TBC1D4	O00141	SGK1	S751	R748S	748	Missense	distal	-3	no	20.327	13.421	EPSD;PhosphoSitePlus	TCGA;COSMIC	9.140	Down-regulation
AGC_SGK_SGK1_ST	O60343	TBC1D4	O00141	SGK1	S751	R748M	748	Missense	distal	-3	no	20.327	10.786	EPSD;PhosphoSitePlus	TCGA;COSMIC	9.140	Down-regulation
AGC_SGK_SGK1_ST	O60343	TBC1D4	O00141	SGK1	T752	K747E	747	Missense	distal	-5	no	10.075	6.544	EPSD	TCGA;COSMIC	9.140	Loss
AGC_SGK_SGK1_ST	O60343	TBC1D4	O00141	SGK1	T752	R748S	748	Missense	distal	-4	no	10.075	10.380	EPSD	TCGA;COSMIC	9.140	Up-regulation
AGC_SGK_SGK1_ST	O60343	TBC1D4	O00141	SGK1	T752	R748M	748	Missense	distal	-4	no	10.075	9.465	EPSD	TCGA;COSMIC	9.140	Down-regulation
AGC_SGK_SGK1_ST	O60343	TBC1D4	O00141	SGK1	S771	R773W	773	Missense	proximal	2	no	10.734	10.878	EPSD	TCGA;COSMIC	9.140	Up-regulation
AGC_SGK_SGK1_ST	O60343	TBC1D4	O00141	SGK1	S771	V765A	765	Missense	distal	-6	no	10.734	11.127	EPSD	TCGA;COSMIC	9.140	Up-regulation
AGC_SGK_SGK1_ST	O60343	TBC1D4	O00141	SGK1	S782	P788S	788	Missense	distal	6	no	10.278	10.480	EPSD	TCGA;COSMIC	9.140	Up-regulation
AGC_SGK_SGK1_ST	O60343	TBC1D4	O00141	SGK1	S1207	E1203D	1203	Missense	distal	-4	no	15.589	15.575	EPSD	TCGA;COSMIC	9.140	Down-regulation
AGC_SGK_SGK1_ST	O60343	TBC1D4	O00141	SGK1	S1207	K1201E	1201	Missense	distal	-6	no	15.589	15.295	EPSD	TCGA;COSMIC	9.140	Down-regulation
AGC_SGK_SGK1_ST	Q9UN36	NDRG2	O00141	SGK1	S346	R345H	345	Missense	proximal	-1	no	14.496	14.383	EPSD;PhosphoSitePlus	TCGA	9.140	Down-regulation
AGC_SGK_SGK1_ST	Q9UN36	NDRG2	O00141	SGK1	T348	R345H	345	Missense	distal	-3	no	19.728	10.109	PhosphoSitePlus;EPSD	TCGA	9.140	Down-regulation
AGC_SGK_SGK1_ST	Q9UN36	NDRG2	O00141	SGK1	S350	R345H	345	Missense	distal	-5	no	16.482	9.150	EPSD	TCGA	9.140	Down-regulation
AGC_SGK_SGK1_ST	Q9UN36	NDRG2	O00141	SGK1	S352	S359Y	359	Missense	distal	7	no	9.627	10.023	EPSD	TCGA;ICGC	9.140	Up-regulation
AGC_SGK_SGK1_ST	Q9UN36	NDRG2	O00141	SGK1	S352	R345H	345	Missense	distal	-7	no	9.627	9.921	EPSD	TCGA	9.140	Up-regulation
AGC_SGK_SGK1_ST	P16220	CREB1	O00141	SGK1	S98	S103A	103	Missense	distal	5	no	16.107	16.097	EPSD	TCGA;COSMIC	9.140	Down-regulation
AGC_SGK_SGK1_ST	P16220	CREB1	O00141	SGK1	T100	S103A	103	Missense	distal	3	no	9.864	9.811	EPSD	TCGA;COSMIC	9.140	Down-regulation
AGC_SGK_SGK1_ST	P16220	CREB1	O00141	SGK1	S133	L128I	128	Missense	distal	-5	no	15.615	13.201	PhosphoSitePlus	TCGA;COSMIC	9.140	Down-regulation
AGC_SGK_SGK1_ST	P10636	MAPT	O00141	SGK1	T167	R168H	168	Missense	proximal	1	no	10.219	10.203	EPSD	TCGA;ICGC;COSMIC	9.140	Down-regulation
AGC_SGK_SGK1_ST	P10636	MAPT	O00141	SGK1	S171	R168H	168	Missense	distal	-3	no	12.821	3.203	EPSD	TCGA;ICGC;COSMIC	9.140	Loss
AGC_SGK_SGK1_ST	P10636	MAPT	O00141	SGK1	S171	R168C	168	Missense	distal	-3	no	12.821	4.759	EPSD	TCGA;ICGC;COSMIC	9.140	Loss
AGC_SGK_SGK1_ST	P10636	MAPT	O00141	SGK1	S214	P212L	212	Missense	proximal	-2	no	13.460	13.835	PhosphoSitePlus	TCGA;ICGC;COSMIC	9.140	Up-regulation
AGC_SGK_SGK1_ST	P10636	MAPT	O00141	SGK1	S214	E220K	220	Missense	distal	6	no	13.460	13.647	PhosphoSitePlus	TCGA;ICGC;COSMIC	9.140	Up-regulation
AGC_SGK_SGK1_ST	P10636	MAPT	O00141	SGK1	S341	E348V	348	Missense	distal	7	no	9.968	10.154	EPSD	TCGA;ICGC;COSMIC	9.140	Up-regulation
AGC_SGK_SGK1_ST	P10636	MAPT	O00141	SGK1	S341	G339R	339	Missense	proximal	-2	no	9.968	10.516	EPSD	TCGA;ICGC;COSMIC	9.140	Up-regulation
AGC_SGK_SGK1_ST	P10636	MAPT	O00141	SGK1	S341	S341F	341	Missense	central	0	yes	9.968	0.000	EPSD	TCGA;ICGC;COSMIC	9.140	Loss
AGC_SGK_SGK1_ST	P10636	MAPT	O00141	SGK1	S369	Q373R	373	Missense	distal	4	no	11.179	11.225	EPSD	TCGA;ICGC;COSMIC	9.140	Up-regulation
AGC_SGK_SGK1_ST	P10636	MAPT	O00141	SGK1	S369	K366E	366	Missense	distal	-3	no	11.179	6.835	EPSD	TCGA;ICGC;COSMIC	9.140	Loss
AGC_SGK_SGK1_ST	P10636	MAPT	O00141	SGK1	S388	G387R	387	Missense	proximal	-1	no	10.775	11.000	EPSD	TCGA;COSMIC	9.140	Up-regulation
AGC_SGK_SGK1_ST	P10636	MAPT	O00141	SGK1	S451	E456K	456	Missense	distal	5	no	16.146	16.207	EPSD	TCGA;ICGC;COSMIC	9.140	Up-regulation
AGC_SGK_SGK1_ST	P10636	MAPT	O00141	SGK1	S451	S452C	452	Missense	proximal	1	no	16.146	16.160	EPSD	TCGA;ICGC;COSMIC	9.140	Up-regulation
AGC_SGK_SGK1_ST	P10636	MAPT	O00141	SGK1	S451	S444F	444	Missense	distal	-7	no	16.146	17.586	EPSD	TCGA;ICGC	9.140	Up-regulation
AGC_SGK_SGK1_ST	P10636	MAPT	O00141	SGK1	S451	S452Y	452	Missense	proximal	1	no	16.146	16.240	EPSD	TCGA;ICGC;COSMIC	9.140	Up-regulation
AGC_SGK_SGK1_ST	P10636	MAPT	O00141	SGK1	T486	A485T	485	Missense	proximal	-1	no	9.480	9.479	EPSD	TCGA;COSMIC;GDSC;CCLE	9.140	Down-regulation
AGC_SGK_SGK1_ST	P10636	MAPT	O00141	SGK1	T486	Q479H	479	Missense	distal	-7	no	9.480	9.245	EPSD	TCGA;COSMIC	9.140	Down-regulation
AGC_SGK_SGK1_ST	P10636	MAPT	O00141	SGK1	T486	P493Q	493	Missense	distal	7	no	9.480	9.339	EPSD	TCGA;COSMIC	9.140	Down-regulation
AGC_SGK_SGK1_ST	Q92542	NCSTN	O00141	SGK1	S437	V439I	439	Missense	proximal	2	no	18.479	18.505	PhosphoSitePlus	TCGA;COSMIC	9.140	Up-regulation
AGC_SGK_SGK1_ST	Q92542	NCSTN	O00141	SGK1	S437	R434G	434	Missense	distal	-3	no	18.479	11.923	PhosphoSitePlus	TCGA;COSMIC	9.140	Down-regulation
AGC_SGK_SGK1_ST	Q92542	NCSTN	O00141	SGK1	S437	R434Q	434	Missense	distal	-3	no	18.479	7.816	PhosphoSitePlus	TCGA;COSMIC;GDSC;CCLE	9.140	Loss
AGC_SGK_SGK1_ST	Q92542	NCSTN	O00141	SGK1	S632	E636Q	636	Missense	distal	4	no	13.327	13.329	EPSD	TCGA;COSMIC	9.140	Up-regulation
AGC_SGK_SGK1_ST	Q92542	NCSTN	O00141	SGK1	S632	A628S	628	Missense	distal	-4	no	13.327	13.441	EPSD	TCGA;COSMIC	9.140	Up-regulation
AGC_SGK_SGK1_ST	P46527	CDKN1B	O00141	SGK1	T157	S161C	161	Missense	distal	4	no	16.770	16.739	PhosphoSitePlus;EPSD	TCGA;ICGC;COSMIC	9.140	Down-regulation
AGC_SGK_SGK1_ST	P46527	CDKN1B	O00141	SGK1	T157	S161Y	161	Missense	distal	4	no	16.770	16.639	PhosphoSitePlus;EPSD	TCGA;ICGC	9.140	Down-regulation
AGC_SGK_SGK1_ST	P46527	CDKN1B	O00141	SGK1	T157	G150E	150	Missense	distal	-7	no	16.770	16.616	PhosphoSitePlus;EPSD	TCGA;ICGC;COSMIC	9.140	Down-regulation
AGC_SGK_SGK1_ST	Q9Y2V2	CARHSP1	O00141	SGK1	S26	R25W	25	Missense	proximal	-1	no	9.859	9.617	EPSD	TCGA;ICGC;COSMIC	9.140	Down-regulation
AGC_SGK_SGK1_ST	Q9Y2V2	CARHSP1	O00141	SGK1	S26	R29H	29	Missense	distal	3	no	9.859	9.793	EPSD	TCGA;ICGC	9.140	Down-regulation
AGC_SGK_SGK1_ST	Q9Y2V2	CARHSP1	O00141	SGK1	S30	R25W	25	Missense	distal	-5	no	19.261	11.604	EPSD	TCGA;ICGC;COSMIC	9.140	Down-regulation
AGC_SGK_SGK1_ST	Q9Y2V2	CARHSP1	O00141	SGK1	S30	R27C	27	Missense	distal	-3	no	19.261	11.199	EPSD	TCGA;ICGC;COSMIC	9.140	Down-regulation
AGC_SGK_SGK1_ST	Q9Y2V2	CARHSP1	O00141	SGK1	S30	G36S	36	Missense	distal	6	no	19.261	19.504	EPSD	TCGA;ICGC;COSMIC	9.140	Up-regulation
AGC_SGK_SGK1_ST	Q9Y2V2	CARHSP1	O00141	SGK1	S30	R29H	29	Missense	proximal	-1	no	19.261	19.149	EPSD	TCGA;ICGC	9.140	Down-regulation
AGC_SGK_SGK1_ST	Q9Y2V2	CARHSP1	O00141	SGK1	S32	R25W	25	Missense	distal	-7	no	17.475	18.590	EPSD	TCGA;ICGC;COSMIC	9.140	Up-regulation
AGC_SGK_SGK1_ST	Q9Y2V2	CARHSP1	O00141	SGK1	S32	R27C	27	Missense	distal	-5	no	17.475	11.213	EPSD	TCGA;ICGC;COSMIC	9.140	Down-regulation
AGC_SGK_SGK1_ST	Q9Y2V2	CARHSP1	O00141	SGK1	S32	G36S	36	Missense	distal	4	no	17.475	17.707	EPSD	TCGA;ICGC;COSMIC	9.140	Up-regulation
AGC_SGK_SGK1_ST	Q9Y2V2	CARHSP1	O00141	SGK1	S32	R29H	29	Missense	distal	-3	no	17.475	7.857	EPSD	TCGA;ICGC	9.140	Loss
AGC_SGK_SGK1_ST	Q9Y2V2	CARHSP1	O00141	SGK1	T50	R56W	56	Missense	distal	6	no	12.625	12.363	EPSD	TCGA;ICGC;COSMIC	9.140	Down-regulation
AGC_SGK_SGK1_ST	Q9Y2V2	CARHSP1	O00141	SGK1	T50	T48M	48	Missense	proximal	-2	no	12.625	12.330	EPSD	TCGA;ICGC;COSMIC	9.140	Down-regulation
AGC_SGK_SGK1_ST	Q9Y2V2	CARHSP1	O00141	SGK1	T50	P44L	44	Missense	distal	-6	no	12.625	12.707	EPSD	TCGA;ICGC;COSMIC	9.140	Up-regulation
AGC_SGK_SGK1_ST	Q9Y2V2	CARHSP1	O00141	SGK1	S52	R56W	56	Missense	distal	4	no	16.115	15.866	PhosphoSitePlus	TCGA;ICGC;COSMIC	9.140	Down-regulation
AGC_SGK_SGK1_ST	Q9Y2V2	CARHSP1	O00141	SGK1	S52	T48M	48	Missense	distal	-4	no	16.115	15.727	PhosphoSitePlus	TCGA;ICGC;COSMIC	9.140	Down-regulation
AGC_SGK_SGK1_ST	Q9Y2V2	CARHSP1	O00141	SGK1	T54	R56W	56	Missense	proximal	2	no	9.750	9.894	EPSD	TCGA;ICGC;COSMIC	9.140	Up-regulation
AGC_SGK_SGK1_ST	Q9Y2V2	CARHSP1	O00141	SGK1	T54	T48M	48	Missense	distal	-6	no	9.750	9.631	EPSD	TCGA;ICGC;COSMIC	9.140	Down-regulation
AGC_SGK_SGK1_ST	Q9Y2V2	CARHSP1	O00141	SGK1	T54	P61S	61	Missense	distal	7	no	9.750	9.357	EPSD	TCGA;ICGC;COSMIC	9.140	Down-regulation
AGC_SGK_SGK1_ST	Q9H4A3	WNK1	O00141	SGK1	T60	D62G	62	Missense	proximal	2	no	16.959	17.182	PhosphoSitePlus	TCGA;ICGC;COSMIC	9.140	Up-regulation
AGC_SGK_SGK1_ST	Q9H4A3	WNK1	O00141	SGK1	T71	T74A	74	Missense	distal	3	no	11.162	11.284	EPSD	TCGA;ICGC;COSMIC	9.140	Up-regulation
AGC_SGK_SGK1_ST	Q9H4A3	WNK1	O00141	SGK1	S167	T160N	160	Missense	distal	-7	no	13.383	13.246	EPSD	TCGA;ICGC;COSMIC	9.140	Down-regulation
AGC_SGK_SGK1_ST	Q9H4A3	WNK1	O00141	SGK1	S167	V172E	172	Missense	distal	5	no	13.383	13.431	EPSD	TCGA;ICGC;COSMIC	9.140	Up-regulation
AGC_SGK_SGK1_ST	Q9H4A3	WNK1	O00141	SGK1	S185	R182T	182	Missense	distal	-3	no	9.265	3.917	EPSD	TCGA;ICGC;COSMIC	9.140	Loss
AGC_SGK_SGK1_ST	Q9H4A3	WNK1	O00141	SGK1	S378	L374Q	374	Missense	distal	-4	no	9.362	9.315	EPSD	TCGA;ICGC;COSMIC	9.140	Down-regulation
AGC_SGK_SGK1_ST	Q9H4A3	WNK1	O00141	SGK1	S378	R376W	376	Missense	proximal	-2	no	9.362	8.608	EPSD	TCGA;ICGC	9.140	Loss
AGC_SGK_SGK1_ST	Q9H4A3	WNK1	O00141	SGK1	T436	R433L	433	Missense	distal	-3	no	9.224	3.876	EPSD	TCGA;ICGC;COSMIC	9.140	Loss
AGC_SGK_SGK1_ST	Q9H4A3	WNK1	O00141	SGK1	T436	R434H	434	Missense	proximal	-2	no	9.224	8.787	EPSD	TCGA;ICGC;COSMIC	9.140	Loss
AGC_SGK_SGK1_ST	Q9H4A3	WNK1	O00141	SGK1	S437	R433L	433	Missense	distal	-4	no	14.220	13.805	EPSD	TCGA;ICGC;COSMIC	9.140	Down-regulation
AGC_SGK_SGK1_ST	Q9H4A3	WNK1	O00141	SGK1	S437	R434H	434	Missense	distal	-3	no	14.220	4.602	EPSD	TCGA;ICGC;COSMIC	9.140	Loss
AGC_SGK_SGK1_ST	Q9H4A3	WNK1	O00141	SGK1	S1105	R1109L	1109	Missense	distal	4	no	16.009	15.932	EPSD	TCGA;COSMIC	9.140	Down-regulation
AGC_SGK_SGK1_ST	Q9H4A3	WNK1	O00141	SGK1	S1105	R1109H	1109	Missense	distal	4	no	16.009	16.038	EPSD	TCGA	9.140	Up-regulation
AGC_SGK_SGK1_ST	Q9H4A3	WNK1	O00141	SGK1	S1105	R1100W	1100	Missense	distal	-5	no	16.009	8.351	EPSD	TCGA;COSMIC	9.140	Loss
AGC_SGK_SGK1_ST	Q9H4A3	WNK1	O00141	SGK1	S1105	R1111Q	1111	Missense	distal	6	no	16.009	15.931	EPSD	TCGA	9.140	Down-regulation
AGC_SGK_SGK1_ST	Q9H4A3	WNK1	O00141	SGK1	S1108	R1109L	1109	Missense	proximal	1	no	10.429	10.474	EPSD	TCGA;COSMIC	9.140	Up-regulation
AGC_SGK_SGK1_ST	Q9H4A3	WNK1	O00141	SGK1	S1108	R1109H	1109	Missense	proximal	1	no	10.429	10.413	EPSD	TCGA	9.140	Down-regulation
AGC_SGK_SGK1_ST	Q9H4A3	WNK1	O00141	SGK1	S1108	R1111Q	1111	Missense	distal	3	no	10.429	10.305	EPSD	TCGA	9.140	Down-regulation
AGC_SGK_SGK1_ST	Q9H4A3	WNK1	O00141	SGK1	S1110	R1109L	1109	Missense	proximal	-1	no	10.760	10.646	EPSD	TCGA;COSMIC	9.140	Down-regulation
AGC_SGK_SGK1_ST	Q9H4A3	WNK1	O00141	SGK1	S1110	R1109H	1109	Missense	proximal	-1	no	10.760	10.647	EPSD	TCGA	9.140	Down-regulation
AGC_SGK_SGK1_ST	Q9H4A3	WNK1	O00141	SGK1	S1110	R1111Q	1111	Missense	proximal	1	no	10.760	10.798	EPSD	TCGA	9.140	Up-regulation
AGC_SGK_SGK1_ST	Q9H4A3	WNK1	O00141	SGK1	S1116	R1109L	1109	Missense	distal	-7	no	9.497	10.178	EPSD	TCGA;COSMIC	9.140	Up-regulation
AGC_SGK_SGK1_ST	Q9H4A3	WNK1	O00141	SGK1	S1116	R1109H	1109	Missense	distal	-7	no	9.497	9.791	EPSD	TCGA	9.140	Up-regulation
AGC_SGK_SGK1_ST	Q9H4A3	WNK1	O00141	SGK1	S1116	R1111Q	1111	Missense	distal	-5	no	9.497	1.346	EPSD	TCGA	9.140	Loss
AGC_SGK_SGK1_ST	Q9H4A3	WNK1	O00141	SGK1	S1261	A1254V	1254	Missense	distal	-7	no	8.357	9.327	EPSD	TCGA;COSMIC;CCLE	9.140	Gain
AGC_SGK_SGK1_ST	Q9H4A3	WNK1	O00141	SGK1	S1289	H1296D	1296	Missense	distal	7	no	12.903	13.035	EPSD	TCGA;COSMIC	9.140	Up-regulation
AGC_SGK_SGK1_ST	Q9H4A3	WNK1	O00141	SGK1	S1289	S1289N	1289	Missense	central	0	yes	12.903	0.000	EPSD	TCGA	9.140	Loss
AGC_SGK_SGK1_ST	Q9H4A3	WNK1	O00141	SGK1	T2128	S2135F	2135	Missense	distal	7	no	16.442	17.126	EPSD	TCGA	9.140	Up-regulation
AGC_SGK_SGK1_ST	Q9H4A3	WNK1	O00141	SGK1	S2133	S2135F	2135	Missense	proximal	2	no	9.009	9.624	EPSD	TCGA	9.140	Gain
AGC_SGK_SGK1_ST	Q9H4A3	WNK1	O00141	SGK1	S2139	S2145N	2145	Missense	distal	6	no	9.376	9.329	EPSD	TCGA;COSMIC	9.140	Down-regulation
AGC_SGK_SGK1_ST	Q9H4A3	WNK1	O00141	SGK1	S2139	S2135F	2135	Missense	distal	-4	no	9.376	7.200	EPSD	TCGA	9.140	Loss
AGC_SGK_SGK1_ST	Q9H4A3	WNK1	O00141	SGK1	S2140	S2145N	2145	Missense	distal	5	no	13.307	13.289	EPSD	TCGA;COSMIC	9.140	Down-regulation
AGC_SGK_SGK1_ST	Q9H4A3	WNK1	O00141	SGK1	S2140	S2135F	2135	Missense	distal	-5	no	13.307	10.550	EPSD	TCGA	9.140	Down-regulation
AGC_SGK_SGK1_ST	Q9H4A3	WNK1	O00141	SGK1	T2245	H2251P	2251	Missense	distal	6	no	11.723	11.612	EPSD	TCGA;COSMIC	9.140	Down-regulation
AGC_SGK_SGK1_ST	Q9H4A3	WNK1	O00141	SGK1	T2245	T2239M	2239	Missense	distal	-6	no	11.723	11.604	EPSD	TCGA;COSMIC	9.140	Down-regulation
AGC_SGK_SGK1_ST	Q9H4A3	WNK1	O00141	SGK1	T2247	H2251P	2251	Missense	distal	4	no	9.697	9.516	EPSD	TCGA;COSMIC	9.140	Down-regulation
AGC_SGK_SGK1_ST	Q9H4A3	WNK1	O00141	SGK1	S2270	S2265L	2265	Missense	distal	-5	no	9.019	10.036	EPSD	TCGA;COSMIC	9.140	Gain
AGC_SGK_SGK1_ST	Q9BUB5	MKNK1	O00141	SGK1	T37	S39F	39	Missense	proximal	2	no	11.035	11.650	EPSD	TCGA;ICGC;COSMIC	9.140	Up-regulation
AGC_SGK_SGK1_ST	Q9BUB5	MKNK1	O00141	SGK1	S286	V290A	290	Missense	distal	4	no	8.889	9.198	EPSD	TCGA;COSMIC	9.140	Gain
AGC_SGK_SGK1_ST	Q9BUB5	MKNK1	O00141	SGK1	S394	F401L	401	Missense	distal	7	no	14.625	14.283	EPSD	TCGA;COSMIC	9.140	Down-regulation
AGC_SGK_SGK1_ST	Q9BUB5	MKNK1	O00141	SGK1	S413	R410H	410	Missense	distal	-3	no	13.281	3.662	EPSD	TCGA;COSMIC	9.140	Loss
AGC_SGK_SGK1_ST	Q9BUB5	MKNK1	O00141	SGK1	S413	E416K	416	Missense	distal	3	no	13.281	13.600	EPSD	TCGA;COSMIC	9.140	Up-regulation
AGC_SGK_SGK1_ST	Q9BUB5	MKNK1	O00141	SGK1	S413	Q414E	414	Missense	proximal	1	no	13.281	13.260	EPSD	TCGA;COSMIC;GDSC;CCLE	9.140	Down-regulation
AGC_SGK_SGK1_ST	P14672	SLC2A4	O00141	SGK1	S274	E270Q	270	Missense	distal	-4	no	17.937	17.844	PhosphoSitePlus	TCGA;ICGC;COSMIC	9.140	Down-regulation
AGC_SGK_SGK1_ST	P14672	SLC2A4	O00141	SGK1	S274	G280S	280	Missense	distal	6	no	17.937	18.180	PhosphoSitePlus	TCGA;ICGC;COSMIC	9.140	Up-regulation
AGC_SGK_SGK1_ST	O43524	FOXO3	O00141	SGK1	S75	D68Y	68	Missense	distal	-7	no	10.869	11.103	EPSD	TCGA;ICGC;COSMIC	9.140	Up-regulation
AGC_SGK_SGK1_ST	O43524	FOXO3	O00141	SGK1	S253	R248Q	248	Missense	distal	-5	no	17.222	9.071	EPSD	TCGA;ICGC;COSMIC	9.140	Loss
AGC_SGK_SGK1_ST	O43524	FOXO3	O00141	SGK1	S253	R250W	250	Missense	distal	-3	no	17.222	7.527	EPSD	TCGA;ICGC;COSMIC	9.140	Loss
AGC_SGK_SGK1_ST	O43524	FOXO3	O00141	SGK1	S253	R250Q	250	Missense	distal	-3	no	17.222	6.560	EPSD	TCGA;ICGC;COSMIC	9.140	Loss
AGC_SGK_SGK1_ST	O43524	FOXO3	O00141	SGK1	S299	L303M	303	Missense	distal	4	no	10.526	10.487	EPSD	TCGA;ICGC	9.140	Down-regulation
AGC_SGK_SGK1_ST	O43524	FOXO3	O00141	SGK1	S299	A305V	305	Missense	distal	6	no	10.526	10.233	EPSD	TCGA;ICGC;COSMIC	9.140	Down-regulation
AGC_SGK_SGK1_ST	O43524	FOXO3	O00141	SGK1	S299	S299I	299	Missense	central	0	yes	10.526	0.000	EPSD	TCGA;ICGC;COSMIC	9.140	Loss
AGC_SGK_SGK1_ST	O43524	FOXO3	O00141	SGK1	S299	R298C	298	Missense	proximal	-1	no	10.526	10.406	EPSD	TCGA;ICGC	9.140	Down-regulation
AGC_SGK_SGK1_ST	O43524	FOXO3	O00141	SGK1	S299	G293D	293	Missense	distal	-6	no	10.526	10.574	EPSD	TCGA;ICGC;COSMIC	9.140	Up-regulation
AGC_SGK_SGK1_ST	O43524	FOXO3	O00141	SGK1	T313	D308Y	308	Missense	distal	-5	no	6.743	9.404	EPSD	TCGA;ICGC;COSMIC	9.140	Gain
AGC_SGK_SGK1_ST	O43524	FOXO3	O00141	SGK1	S315	R310C	310	Missense	distal	-5	no	19.864	13.602	PhosphoSitePlus	TCGA;ICGC;COSMIC	9.140	Down-regulation
AGC_SGK_SGK1_ST	O43524	FOXO3	O00141	SGK1	S315	D308Y	308	Missense	distal	-7	no	19.864	20.097	PhosphoSitePlus	TCGA;ICGC;COSMIC	9.140	Up-regulation
AGC_SGK_SGK1_ST	O43524	FOXO3	O00141	SGK1	S315	S315F	315	Missense	central	0	yes	19.864	0.000	PhosphoSitePlus	TCGA;ICGC;COSMIC	9.140	Loss
AGC_SGK_SGK1_ST	O43524	FOXO3	O00141	SGK1	S315	R312C	312	Missense	distal	-3	no	19.864	11.802	PhosphoSitePlus	TCGA;ICGC;COSMIC	9.140	Down-regulation
AGC_SGK_SGK1_ST	O43524	FOXO3	O00141	SGK1	S318	R323L	323	Missense	distal	5	no	10.089	10.060	EPSD	TCGA;ICGC;COSMIC	9.140	Down-regulation
AGC_SGK_SGK1_ST	O43524	FOXO3	O00141	SGK1	S318	S315F	315	Missense	distal	-3	no	10.089	6.872	EPSD	TCGA;ICGC;COSMIC	9.140	Loss
AGC_SGK_SGK1_ST	O43524	FOXO3	O00141	SGK1	S318	R312C	312	Missense	distal	-6	no	10.089	10.024	EPSD	TCGA;ICGC;COSMIC	9.140	Down-regulation
AGC_SGK_SGK1_ST	O43524	FOXO3	O00141	SGK1	S357	C362F	362	Missense	distal	5	no	10.122	10.028	EPSD	TCGA;ICGC;COSMIC	9.140	Down-regulation
AGC_SGK_SGK1_ST	O43524	FOXO3	O00141	SGK1	S413	S412C	412	Missense	proximal	-1	no	10.023	9.927	EPSD	TCGA;ICGC;COSMIC	9.140	Down-regulation
AGC_SGK_SGK1_ST	O43524	FOXO3	O00141	SGK1	S421	L423M	423	Missense	proximal	2	no	10.400	10.424	EPSD	TCGA;ICGC	9.140	Up-regulation
AGC_SGK_SGK1_ST	O43524	FOXO3	O00141	SGK1	S421	S425F	425	Missense	distal	4	no	10.400	9.957	EPSD	TCGA;ICGC;COSMIC	9.140	Down-regulation
AGC_SGK_SGK1_ST	O43524	FOXO3	O00141	SGK1	S551	S553Y	553	Missense	proximal	2	no	11.866	12.131	EPSD	TCGA;ICGC;COSMIC	9.140	Up-regulation
AGC_SGK_SGK1_ST	O43524	FOXO3	O00141	SGK1	S553	S560I	560	Missense	distal	7	no	13.827	14.246	EPSD	TCGA;ICGC;COSMIC	9.140	Up-regulation
AGC_SGK_SGK1_ST	O43524	FOXO3	O00141	SGK1	S553	S553Y	553	Missense	central	0	yes	13.827	0.000	EPSD	TCGA;ICGC;COSMIC	9.140	Loss
AGC_SGK_SGK1_ST	O43524	FOXO3	O00141	SGK1	S588	D585A	585	Missense	distal	-3	no	6.604	10.497	EPSD	TCGA;ICGC;COSMIC	9.140	Gain
AGC_SGK_SGK1_ST	P28482	MAPK1	O00141	SGK1	S29	G34C	34	Missense	distal	5	no	11.990	12.013	PhosphoSitePlus	TCGA;ICGC;COSMIC;CCLE	9.140	Up-regulation
AGC_SGK_SGK1_ST	P28482	MAPK1	O00141	SGK1	T190	R191H	191	Missense	proximal	1	no	9.577	9.562	EPSD	TCGA;ICGC;COSMIC	9.140	Down-regulation
AGC_SGK_SGK1_ST	Q96J92	WNK4	O00141	SGK1	S47	P54S	54	Missense	distal	7	no	18.127	17.734	EPSD	TCGA;ICGC;COSMIC	9.140	Down-regulation
AGC_SGK_SGK1_ST	Q96J92	WNK4	O00141	SGK1	S575	A574G	574	Missense	proximal	-1	no	14.039	13.873	EPSD	TCGA;ICGC;COSMIC	9.140	Down-regulation
AGC_SGK_SGK1_ST	Q96J92	WNK4	O00141	SGK1	S575	L570F	570	Missense	distal	-5	no	14.039	10.266	EPSD	TCGA;ICGC;COSMIC	9.140	Down-regulation
AGC_SGK_SGK1_ST	Q96J92	WNK4	O00141	SGK1	S680	R687T	687	Missense	distal	7	no	17.705	17.747	EPSD	TCGA;ICGC;COSMIC	9.140	Up-regulation
AGC_SGK_SGK1_ST	Q96J92	WNK4	O00141	SGK1	S682	R687T	687	Missense	distal	5	no	10.977	10.976	EPSD	TCGA;ICGC;COSMIC	9.140	Down-regulation
AGC_SGK_SGK1_ST	Q96J92	WNK4	O00141	SGK1	S1054	E1052K	1052	Missense	proximal	-2	no	9.145	9.443	EPSD	TCGA;ICGC;COSMIC	9.140	Up-regulation
AGC_SGK_SGK1_ST	Q96J92	WNK4	O00141	SGK1	S1190	R1185C	1185	Missense	distal	-5	no	19.299	13.037	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	9.140	Down-regulation
AGC_SGK_SGK1_ST	Q96J92	WNK4	O00141	SGK1	S1201	P1208Q	1208	Missense	distal	7	no	17.787	17.646	PhosphoSitePlus;EPSD	TCGA;ICGC;COSMIC	9.140	Down-regulation
AGC_SGK_SGK1_ST	Q96J92	WNK4	O00141	SGK1	S1217	I1212N	1212	Missense	distal	-5	no	12.893	12.772	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	9.140	Down-regulation
AGC_SGK_SGK1_ST	Q9Y2I7	PIKFYVE	O00141	SGK1	T22	R19Q	19	Missense	distal	-3	no	12.881	2.218	EPSD	TCGA;ICGC;COSMIC	9.140	Loss
AGC_SGK_SGK1_ST	Q9Y2I7	PIKFYVE	O00141	SGK1	S25	R19Q	19	Missense	distal	-6	no	10.456	10.335	EPSD	TCGA;ICGC;COSMIC	9.140	Down-regulation
AGC_SGK_SGK1_ST	Q9Y2I7	PIKFYVE	O00141	SGK1	S105	S104C	104	Missense	proximal	-1	no	12.382	12.286	EPSD	TCGA;ICGC;COSMIC	9.140	Down-regulation
AGC_SGK_SGK1_ST	Q9Y2I7	PIKFYVE	O00141	SGK1	S105	R103L	103	Missense	proximal	-2	no	12.382	12.172	EPSD	TCGA;ICGC;COSMIC	9.140	Down-regulation
AGC_SGK_SGK1_ST	Q9Y2I7	PIKFYVE	O00141	SGK1	S105	R111K	111	Missense	distal	6	no	12.382	12.527	EPSD	TCGA;ICGC;COSMIC	9.140	Up-regulation
AGC_SGK_SGK1_ST	Q9Y2I7	PIKFYVE	O00141	SGK1	S105	R103H	103	Missense	proximal	-2	no	12.382	11.945	EPSD	TCGA;ICGC;COSMIC	9.140	Down-regulation
AGC_SGK_SGK1_ST	Q9Y2I7	PIKFYVE	O00141	SGK1	S223	L218S	218	Missense	distal	-5	no	12.585	11.568	EPSD	TCGA	9.140	Down-regulation
AGC_SGK_SGK1_ST	Q9Y2I7	PIKFYVE	O00141	SGK1	S223	A221S	221	Missense	proximal	-2	no	12.585	12.555	EPSD	TCGA;ICGC;COSMIC	9.140	Down-regulation
AGC_SGK_SGK1_ST	Q9Y2I7	PIKFYVE	O00141	SGK1	S223	D225Y	225	Missense	proximal	2	no	12.585	12.746	EPSD	TCGA;ICGC;COSMIC	9.140	Up-regulation
AGC_SGK_SGK1_ST	Q9Y2I7	PIKFYVE	O00141	SGK1	S261	R262H	262	Missense	proximal	1	no	10.542	10.526	EPSD	TCGA;ICGC	9.140	Down-regulation
AGC_SGK_SGK1_ST	Q9Y2I7	PIKFYVE	O00141	SGK1	S291	V290A	290	Missense	proximal	-1	no	10.858	11.043	EPSD	TCGA;ICGC;COSMIC;GDSC	9.140	Up-regulation
AGC_SGK_SGK1_ST	Q9Y2I7	PIKFYVE	O00141	SGK1	S307	S305L	305	Missense	proximal	-2	no	19.074	18.962	EPSD	TCGA;ICGC;COSMIC	9.140	Down-regulation
AGC_SGK_SGK1_ST	Q9Y2I7	PIKFYVE	O00141	SGK1	S307	A306T	306	Missense	proximal	-1	no	19.074	19.072	EPSD	TCGA;ICGC;COSMIC	9.140	Down-regulation
AGC_SGK_SGK1_ST	Q9Y2I7	PIKFYVE	O00141	SGK1	T309	S305L	305	Missense	distal	-4	no	13.071	12.351	EPSD	TCGA;ICGC;COSMIC	9.140	Down-regulation
AGC_SGK_SGK1_ST	Q9Y2I7	PIKFYVE	O00141	SGK1	T309	A306T	306	Missense	distal	-3	no	13.071	13.010	EPSD	TCGA;ICGC;COSMIC	9.140	Down-regulation
AGC_SGK_SGK1_ST	Q9Y2I7	PIKFYVE	O00141	SGK1	S312	S305L	305	Missense	distal	-7	no	8.581	9.240	EPSD	TCGA;ICGC;COSMIC	9.140	Gain
AGC_SGK_SGK1_ST	Q9Y2I7	PIKFYVE	O00141	SGK1	S329	R334Q	334	Missense	distal	5	no	11.434	11.405	EPSD	TCGA;ICGC	9.140	Down-regulation
AGC_SGK_SGK1_ST	Q9Y2I7	PIKFYVE	O00141	SGK1	T341	R334Q	334	Missense	distal	-7	no	10.930	11.459	EPSD	TCGA;ICGC	9.140	Up-regulation
AGC_SGK_SGK1_ST	Q9Y2I7	PIKFYVE	O00141	SGK1	T380	Y376C	376	Missense	distal	-4	no	8.987	9.292	EPSD	TCGA;ICGC;COSMIC	9.140	Gain
AGC_SGK_SGK1_ST	Q9Y2I7	PIKFYVE	O00141	SGK1	S845	I839V	839	Missense	distal	-6	no	12.828	12.753	EPSD	TCGA;ICGC;COSMIC	9.140	Down-regulation
AGC_SGK_SGK1_ST	Q9Y2I7	PIKFYVE	O00141	SGK1	S845	D846G	846	Missense	proximal	1	no	12.828	12.935	EPSD	TCGA;ICGC;COSMIC	9.140	Up-regulation
AGC_SGK_SGK1_ST	Q9Y2I7	PIKFYVE	O00141	SGK1	S1111	L1110V	1110	Missense	proximal	-1	no	12.503	12.373	EPSD	TCGA;ICGC;COSMIC	9.140	Down-regulation
AGC_SGK_SGK1_ST	Q9Y2I7	PIKFYVE	O00141	SGK1	S1111	S1111C	1111	Missense	central	0	yes	12.503	0.000	EPSD	TCGA;ICGC;COSMIC	9.140	Loss
AGC_SGK_SGK1_ST	Q9Y2I7	PIKFYVE	O00141	SGK1	S1111	D1109Y	1109	Missense	proximal	-2	no	12.503	12.635	EPSD	TCGA;ICGC	9.140	Up-regulation
AGC_SGK_SGK1_ST	Q9Y2I7	PIKFYVE	O00141	SGK1	S1177	K1174R	1174	Missense	distal	-3	no	7.086	13.173	EPSD	TCGA;ICGC;COSMIC	9.140	Gain
AGC_SGK_SGK1_ST	Q9Y2I7	PIKFYVE	O00141	SGK1	S1474	Q1469H	1469	Missense	distal	-5	no	8.914	9.732	EPSD	TCGA;ICGC;COSMIC	9.140	Gain
AGC_SGK_SGK1_ST	Q9Y2I7	PIKFYVE	O00141	SGK1	S1549	P1545S	1545	Missense	distal	-4	no	12.337	13.349	EPSD	TCGA;ICGC;COSMIC	9.140	Up-regulation
AGC_SGK_SGK1_ST	Q9Y2I7	PIKFYVE	O00141	SGK1	S1708	S1704N	1704	Missense	distal	-4	no	9.197	8.680	EPSD	TCGA;ICGC;COSMIC	9.140	Loss
AGC_SGK_SGK1_ST	Q9Y2I7	PIKFYVE	O00141	SGK1	S1714	P1719L	1719	Missense	distal	5	no	15.084	15.106	EPSD	TCGA;ICGC;COSMIC	9.140	Up-regulation
AGC_SGK_SGK1_ST	Q9Y2I7	PIKFYVE	O00141	SGK1	S1722	P1719L	1719	Missense	distal	-3	no	10.516	17.265	EPSD	TCGA;ICGC;COSMIC	9.140	Up-regulation
AGC_SGK_SGK1_ST	Q9Y2I7	PIKFYVE	O00141	SGK1	S1722	R1728C	1728	Missense	distal	6	no	10.516	10.503	EPSD	TCGA;ICGC;COSMIC	9.140	Down-regulation
AGC_SGK_SGK1_ST	Q9Y2I7	PIKFYVE	O00141	SGK1	S2004	I2002M	2002	Missense	proximal	-2	no	13.672	13.692	EPSD	TCGA;ICGC;COSMIC	9.140	Up-regulation
AGC_SGK_SGK1_ST	Q9Y2I7	PIKFYVE	O00141	SGK1	S2004	V1997L	1997	Missense	distal	-7	no	13.672	13.185	EPSD	TCGA;ICGC;COSMIC	9.140	Down-regulation
AGC_SGK_SGK1_ST	Q6R327	RICTOR	O00141	SGK1	S21	R18L	18	Missense	distal	-3	no	19.124	13.775	EPSD	TCGA;ICGC;COSMIC	9.140	Down-regulation
AGC_SGK_SGK1_ST	Q6R327	RICTOR	O00141	SGK1	S35	D36N	36	Missense	proximal	1	no	13.983	13.853	EPSD	TCGA;ICGC;COSMIC	9.140	Down-regulation
AGC_SGK_SGK1_ST	Q6R327	RICTOR	O00141	SGK1	S35	L42F	42	Missense	distal	7	no	13.983	14.326	EPSD	TCGA;ICGC;COSMIC	9.140	Up-regulation
AGC_SGK_SGK1_ST	Q6R327	RICTOR	O00141	SGK1	S35	E40K	40	Missense	distal	5	no	13.983	14.044	EPSD	TCGA;ICGC;COSMIC	9.140	Up-regulation
AGC_SGK_SGK1_ST	Q6R327	RICTOR	O00141	SGK1	S35	L30V	30	Missense	distal	-5	no	13.983	9.093	EPSD	TCGA;ICGC;COSMIC	9.140	Loss
AGC_SGK_SGK1_ST	Q6R327	RICTOR	O00141	SGK1	S383	H379R	379	Missense	distal	-4	no	11.689	12.106	EPSD	TCGA;ICGC;COSMIC	9.140	Up-regulation
AGC_SGK_SGK1_ST	Q6R327	RICTOR	O00141	SGK1	S383	R380H	380	Missense	distal	-3	no	11.689	2.070	EPSD	TCGA;ICGC;COSMIC	9.140	Loss
AGC_SGK_SGK1_ST	Q6R327	RICTOR	O00141	SGK1	S703	D710N	710	Missense	distal	7	no	11.742	11.585	EPSD	TCGA;ICGC;COSMIC	9.140	Down-regulation
AGC_SGK_SGK1_ST	Q6R327	RICTOR	O00141	SGK1	S810	R807I	807	Missense	distal	-3	no	12.466	3.923	EPSD	TCGA;COSMIC	9.140	Loss
AGC_SGK_SGK1_ST	Q6R327	RICTOR	O00141	SGK1	S1035	S1042L	1042	Missense	distal	7	no	12.473	12.814	EPSD	TCGA;ICGC;COSMIC	9.140	Up-regulation
AGC_SGK_SGK1_ST	Q6R327	RICTOR	O00141	SGK1	S1035	E1038G	1038	Missense	distal	3	no	12.473	12.490	EPSD	TCGA;ICGC;COSMIC	9.140	Up-regulation
AGC_SGK_SGK1_ST	Q6R327	RICTOR	O00141	SGK1	S1121	G1117E	1117	Missense	distal	-4	no	9.482	9.506	EPSD	TCGA;ICGC;COSMIC	9.140	Up-regulation
AGC_SGK_SGK1_ST	Q6R327	RICTOR	O00141	SGK1	S1121	L1120V	1120	Missense	proximal	-1	no	9.482	9.352	EPSD	TCGA;ICGC	9.140	Down-regulation
AGC_SGK_SGK1_ST	Q6R327	RICTOR	O00141	SGK1	T1133	T1135M	1135	Missense	proximal	2	no	11.807	11.926	EPSD	TCGA;ICGC;COSMIC	9.140	Up-regulation
AGC_SGK_SGK1_ST	Q6R327	RICTOR	O00141	SGK1	T1133	R1130Q	1130	Missense	distal	-3	no	11.807	1.144	EPSD	TCGA;ICGC;COSMIC;GDSC;CCLE	9.140	Loss
AGC_SGK_SGK1_ST	Q6R327	RICTOR	O00141	SGK1	T1135	T1135M	1135	Missense	central	0	yes	19.326	0.000	PhosphoSitePlus	TCGA;ICGC;COSMIC	9.140	Loss
AGC_SGK_SGK1_ST	Q6R327	RICTOR	O00141	SGK1	T1135	R1130Q	1130	Missense	distal	-5	no	19.326	11.175	PhosphoSitePlus	TCGA;ICGC;COSMIC;GDSC;CCLE	9.140	Down-regulation
AGC_SGK_SGK1_ST	Q6R327	RICTOR	O00141	SGK1	S1138	T1135M	1135	Missense	distal	-3	no	12.757	8.563	EPSD	TCGA;ICGC;COSMIC	9.140	Loss
AGC_SGK_SGK1_ST	Q6R327	RICTOR	O00141	SGK1	S1162	H1168Y	1168	Missense	distal	6	no	10.736	10.690	EPSD	TCGA;ICGC;COSMIC	9.140	Down-regulation
AGC_SGK_SGK1_ST	Q6R327	RICTOR	O00141	SGK1	S1162	K1167E	1167	Missense	distal	5	no	10.736	10.675	EPSD	TCGA;ICGC;COSMIC	9.140	Down-regulation
AGC_SGK_SGK1_ST	Q6R327	RICTOR	O00141	SGK1	S1162	Q1158H	1158	Missense	distal	-4	no	10.736	10.780	EPSD	TCGA;ICGC;COSMIC	9.140	Up-regulation
AGC_SGK_SGK1_ST	Q6R327	RICTOR	O00141	SGK1	S1177	T1172I	1172	Missense	distal	-5	no	9.303	6.833	EPSD	TCGA	9.140	Loss
AGC_SGK_SGK1_ST	Q6R327	RICTOR	O00141	SGK1	S1177	K1184Q	1184	Missense	distal	7	no	9.303	9.662	EPSD	TCGA;ICGC;COSMIC	9.140	Up-regulation
AGC_SGK_SGK1_ST	Q6R327	RICTOR	O00141	SGK1	S1219	T1222I	1222	Missense	distal	3	no	14.980	14.668	EPSD	TCGA;ICGC;COSMIC	9.140	Down-regulation
AGC_SGK_SGK1_ST	Q6R327	RICTOR	O00141	SGK1	S1219	R1216H	1216	Missense	distal	-3	no	14.980	5.361	EPSD	TCGA;ICGC;COSMIC;CCLE	9.140	Loss
AGC_SGK_SGK1_ST	Q6R327	RICTOR	O00141	SGK1	S1227	T1222I	1222	Missense	distal	-5	no	11.248	8.778	EPSD	TCGA;ICGC;COSMIC	9.140	Loss
AGC_SGK_SGK1_ST	Q6R327	RICTOR	O00141	SGK1	S1353	P1354S	1354	Missense	proximal	1	no	9.383	9.270	EPSD	TCGA;ICGC;COSMIC	9.140	Down-regulation
AGC_SGK_SGK1_ST	Q6R327	RICTOR	O00141	SGK1	S1353	S1346C	1346	Missense	distal	-7	no	9.383	9.772	EPSD	TCGA;ICGC;COSMIC	9.140	Up-regulation
AGC_SGK_SGK1_ST	Q6R327	RICTOR	O00141	SGK1	S1378	K1382Q	1382	Missense	distal	4	no	10.137	9.859	EPSD	TCGA;ICGC	9.140	Down-regulation
AGC_SGK_SGK1_ST	Q6R327	RICTOR	O00141	SGK1	S1378	M1381V	1381	Missense	distal	3	no	10.137	9.830	EPSD	TCGA;ICGC;COSMIC	9.140	Down-regulation
AGC_SGK_SGK1_ST	Q6R327	RICTOR	O00141	SGK1	S1378	S1378N	1378	Missense	central	0	yes	10.137	0.000	EPSD	TCGA;ICGC;COSMIC	9.140	Loss
AGC_SGK_SGK1_ST	Q6R327	RICTOR	O00141	SGK1	S1408	S1407F	1407	Missense	proximal	-1	no	10.658	10.349	EPSD	TCGA;ICGC;COSMIC	9.140	Down-regulation
AGC_SGK_SGK1_ST	Q6R327	RICTOR	O00141	SGK1	S1408	R1405Q	1405	Missense	distal	-3	no	10.658	-0.005	EPSD	TCGA;ICGC;COSMIC	9.140	Loss
AGC_SGK_SGK1_ST	P45985	MAP2K4	O00141	SGK1	S80	S80N	80	Missense	central	0	yes	20.300	0.000	PhosphoSitePlus	TCGA;COSMIC	9.140	Loss
AGC_SGK_SGK1_ST	P45985	MAP2K4	O00141	SGK1	S80	S83A	83	Missense	distal	3	no	20.300	20.247	PhosphoSitePlus	TCGA	9.140	Down-regulation
AGC_SGK_SGK1_ST	P45985	MAP2K4	O00141	SGK1	S292	W291C	291	Missense	proximal	-1	no	10.208	10.331	EPSD	TCGA;COSMIC	9.140	Up-regulation
AGC_SGK_SGK1_ST	P45985	MAP2K4	O00141	SGK1	S292	R287H	287	Missense	distal	-5	no	10.208	2.876	EPSD	TCGA;COSMIC	9.140	Loss
AGC_SGK_SGK1_ST	O14920	IKBKB	O00141	SGK1	T23	I30M	30	Missense	distal	7	no	11.541	11.418	EPSD	TCGA;COSMIC	9.140	Down-regulation
AGC_SGK_SGK1_ST	O14920	IKBKB	O00141	SGK1	T23	E16K	16	Missense	distal	-7	no	11.541	10.479	EPSD	TCGA;ICGC;COSMIC	9.140	Down-regulation
AGC_SGK_SGK1_ST	O14920	IKBKB	O00141	SGK1	S181	G176D	176	Missense	distal	-5	no	14.076	12.260	PhosphoSitePlus	TCGA;COSMIC	9.140	Down-regulation
AGC_SGK_SGK1_ST	O14920	IKBKB	O00141	SGK1	S181	V183M	183	Missense	proximal	2	no	14.076	13.988	PhosphoSitePlus	TCGA;COSMIC	9.140	Down-regulation
AGC_SGK_SGK1_ST	O14920	IKBKB	O00141	SGK1	S239	H232R	232	Missense	distal	-7	no	9.764	9.470	EPSD	TCGA;COSMIC	9.140	Down-regulation
AGC_SGK_SGK1_ST	O14920	IKBKB	O00141	SGK1	S239	Q237R	237	Missense	proximal	-2	no	9.764	10.218	EPSD	TCGA;COSMIC	9.140	Up-regulation
AGC_SGK_SGK1_ST	O14920	IKBKB	O00141	SGK1	T368	P363R	363	Missense	distal	-5	no	0.273	9.678	EPSD	TCGA;COSMIC	9.140	Gain
AGC_SGK_SGK1_ST	P42858	HTT	O00141	SGK1	S262	R267W	267	Missense	distal	5	no	13.000	12.920	EPSD	TCGA;ICGC;COSMIC	9.140	Down-regulation
AGC_SGK_SGK1_ST	P42858	HTT	O00141	SGK1	S262	R267Q	267	Missense	distal	5	no	13.000	12.971	EPSD	TCGA;ICGC;COSMIC	9.140	Down-regulation
AGC_SGK_SGK1_ST	P42858	HTT	O00141	SGK1	S640	D645Y	645	Missense	distal	5	no	13.413	13.407	EPSD	TCGA;ICGC;COSMIC	9.140	Down-regulation
AGC_SGK_SGK1_ST	P42858	HTT	O00141	SGK1	S689	R686H	686	Missense	distal	-3	no	11.950	2.331	EPSD	TCGA;ICGC	9.140	Loss
AGC_SGK_SGK1_ST	P42858	HTT	O00141	SGK1	S689	G696R	696	Missense	distal	7	no	11.950	11.616	EPSD	TCGA	9.140	Down-regulation
AGC_SGK_SGK1_ST	P42858	HTT	O00141	SGK1	S689	S691L	691	Missense	proximal	2	no	11.950	12.237	EPSD	TCGA;ICGC;COSMIC;CCLE	9.140	Up-regulation
AGC_SGK_SGK1_ST	P42858	HTT	O00141	SGK1	S689	R686C	686	Missense	distal	-3	no	11.950	3.888	EPSD	TCGA;ICGC;COSMIC	9.140	Loss
AGC_SGK_SGK1_ST	P42858	HTT	O00141	SGK1	S1111	E1114K	1114	Missense	distal	3	no	12.659	12.978	EPSD	TCGA;ICGC;COSMIC	9.140	Up-regulation
AGC_SGK_SGK1_ST	P42858	HTT	O00141	SGK1	S1111	S1108L	1108	Missense	distal	-3	no	12.659	14.216	EPSD	TCGA;ICGC;COSMIC	9.140	Up-regulation
AGC_SGK_SGK1_ST	P42858	HTT	O00141	SGK1	S1111	S1104Y	1104	Missense	distal	-7	no	12.659	13.463	EPSD	TCGA;ICGC;COSMIC;GDSC;CCLE	9.140	Up-regulation
AGC_SGK_SGK1_ST	P42858	HTT	O00141	SGK1	S1171	P1170R	1170	Missense	proximal	-1	no	10.038	10.255	EPSD	TCGA;ICGC;COSMIC	9.140	Up-regulation
AGC_SGK_SGK1_ST	P42858	HTT	O00141	SGK1	T1173	P1170R	1170	Missense	distal	-3	no	0.396	12.494	EPSD	TCGA;ICGC;COSMIC	9.140	Gain
AGC_SGK_SGK1_ST	P42858	HTT	O00141	SGK1	S1216	S1210Y	1210	Missense	distal	-6	no	9.201	9.019	EPSD	TCGA;ICGC;COSMIC	9.140	Loss
AGC_SGK_SGK1_ST	P42858	HTT	O00141	SGK1	S1349	P1352L	1352	Missense	distal	3	no	13.169	13.178	EPSD	TCGA;ICGC;COSMIC	9.140	Up-regulation
AGC_SGK_SGK1_ST	P42858	HTT	O00141	SGK1	S1349	S1347F	1347	Missense	proximal	-2	no	13.169	12.327	EPSD	TCGA;ICGC;COSMIC	9.140	Down-regulation
AGC_SGK_SGK1_ST	P42858	HTT	O00141	SGK1	S1349	R1344C	1344	Missense	distal	-5	no	13.169	6.907	EPSD	TCGA;ICGC;COSMIC	9.140	Loss
AGC_SGK_SGK1_ST	P42858	HTT	O00141	SGK1	T2066	L2064V	2064	Missense	proximal	-2	no	13.982	13.307	EPSD	TCGA;ICGC;COSMIC	9.140	Down-regulation
AGC_SGK_SGK1_ST	P42858	HTT	O00141	SGK1	T2066	R2063C	2063	Missense	distal	-3	no	13.982	5.920	EPSD	TCGA;ICGC;COSMIC	9.140	Loss
AGC_SGK_SGK1_ST	P42858	HTT	O00141	SGK1	T2066	R2063L	2063	Missense	distal	-3	no	13.982	8.633	EPSD	TCGA;ICGC;COSMIC	9.140	Loss
AGC_SGK_SGK1_ST	P42858	HTT	O00141	SGK1	T2066	D2060N	2060	Missense	distal	-6	no	13.982	14.114	EPSD	TCGA;ICGC;COSMIC	9.140	Up-regulation
AGC_SGK_SGK1_ST	P42858	HTT	O00141	SGK1	S2089	G2084R	2084	Missense	distal	-5	no	7.532	12.892	EPSD	TCGA;ICGC;COSMIC	9.140	Gain
AGC_SGK_SGK1_ST	P42858	HTT	O00141	SGK1	T2455	T2459A	2459	Missense	distal	4	no	12.258	12.319	EPSD	TCGA;ICGC;COSMIC	9.140	Up-regulation
AGC_SGK_SGK1_ST	P42858	HTT	O00141	SGK1	T2455	R2461C	2461	Missense	distal	6	no	12.258	12.245	EPSD	TCGA;ICGC;COSMIC	9.140	Down-regulation
AGC_SGK_SGK1_ST	P42858	HTT	O00141	SGK1	S2548	F2543C	2543	Missense	distal	-5	no	7.552	9.291	EPSD	TCGA;ICGC;COSMIC	9.140	Gain
AGC_SGK_SGK1_ST	P42858	HTT	O00141	SGK1	T2570	I2568V	2568	Missense	proximal	-2	no	10.575	10.240	EPSD	TCGA;ICGC;COSMIC	9.140	Down-regulation
AGC_SGK_SGK1_ST	P42858	HTT	O00141	SGK1	T2570	S2563L	2563	Missense	distal	-7	no	10.575	11.234	EPSD	TCGA;ICGC;COSMIC	9.140	Up-regulation
AGC_SGK_SGK1_ST	Q969H0	FBXW7	O00141	SGK1	S18	R14Q	14	Missense	distal	-4	no	11.099	10.637	EPSD	TCGA;ICGC;COSMIC;GDSC;CCLE	9.140	Down-regulation
AGC_SGK_SGK1_ST	Q969H0	FBXW7	O00141	SGK1	S227	G233C	233	Missense	distal	6	no	18.838	19.010	PhosphoSitePlus	TCGA;ICGC;COSMIC	9.140	Up-regulation
AGC_SGK_SGK1_ST	Q969H0	FBXW7	O00141	SGK1	T692	R689W	689	Missense	distal	-3	no	13.642	3.947	EPSD	TCGA;ICGC;COSMIC;GDSC;CCLE	9.140	Loss
AGC_SGK_SGK1_ST	Q969H0	FBXW7	O00141	SGK1	T692	R689Q	689	Missense	distal	-3	no	13.642	2.980	EPSD	TCGA;ICGC;COSMIC	9.140	Loss
AGC_SGK_SGK1_ST	P25963	NFKBIA	O00141	SGK1	S32	D31N	31	Missense	proximal	-1	no	14.940	15.032	PhosphoSitePlus	TCGA;ICGC;COSMIC	9.140	Up-regulation
AGC_SGK_SGK1_ST	P25963	NFKBIA	O00141	SGK1	S32	D27H	27	Missense	distal	-5	no	14.940	14.784	PhosphoSitePlus	TCGA;ICGC;COSMIC	9.140	Down-regulation
TK_Jak_JAK1_Y	Q96EB6	SIRT1	P23458	JAK1	Y280	A284V	284	Missense	distal	4	no	14.903	12.125	PhosphoSitePlus;EPSD	TCGA	8.575	Down-regulation
TK_Jak_JAK1_Y	Q96EB6	SIRT1	P23458	JAK1	Y280	F273S	273	Missense	distal	-7	no	14.903	13.781	PhosphoSitePlus;EPSD	TCGA;ICGC	8.575	Down-regulation
TK_Jak_JAK1_Y	Q96EB6	SIRT1	P23458	JAK1	Y280	R282H	282	Missense	proximal	2	no	14.903	14.930	PhosphoSitePlus;EPSD	TCGA;ICGC;COSMIC	8.575	Up-regulation
TK_Jak_JAK1_Y	Q96EB6	SIRT1	P23458	JAK1	Y301	D298H	298	Missense	distal	-3	no	14.399	13.479	EPSD;PhosphoSitePlus	TCGA;COSMIC	8.575	Down-regulation
TK_Jak_JAK1_Y	Q9Y5X2	SNX8	P23458	JAK1	Y95	V97G	97	Missense	proximal	2	no	17.912	17.284	PhosphoSitePlus;EPSD	TCGA;ICGC;COSMIC	8.575	Down-regulation
TK_Jak_JAK1_Y	Q9Y5X2	SNX8	P23458	JAK1	Y95	R101C	101	Missense	distal	6	no	17.912	17.787	PhosphoSitePlus;EPSD	TCGA;ICGC	8.575	Down-regulation
TK_Jak_JAK1_Y	Q9Y5X2	SNX8	P23458	JAK1	Y126	R127H	127	Missense	proximal	1	no	14.341	13.331	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC;GDSC;CCLE	8.575	Down-regulation
TK_Jak_JAK1_Y	Q9Y5X2	SNX8	P23458	JAK1	Y126	P133T	133	Missense	distal	7	no	14.341	14.747	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	8.575	Up-regulation
TK_Jak_JAK1_Y	Q9Y5X2	SNX8	P23458	JAK1	Y126	R127C	127	Missense	proximal	1	no	14.341	14.171	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC;GDSC;CCLE	8.575	Down-regulation
TK_Jak_JAK1_Y	Q99683	MAP3K5	P23458	JAK1	Y574	I577M	577	Missense	distal	3	no	8.938	8.678	EPSD	TCGA;COSMIC	8.575	Down-regulation
TK_Jak_JAK1_Y	Q99683	MAP3K5	P23458	JAK1	Y574	Y570D	570	Missense	distal	-4	no	8.938	8.932	EPSD	TCGA;ICGC	8.575	Down-regulation
TK_Jak_JAK1_Y	Q99683	MAP3K5	P23458	JAK1	Y718	L722P	722	Missense	distal	4	no	13.321	16.074	PhosphoSitePlus	TCGA;ICGC;COSMIC	8.575	Up-regulation
TK_Jak_JAK1_Y	Q99683	MAP3K5	P23458	JAK1	Y961	S966F	966	Missense	distal	5	no	9.213	9.693	EPSD	TCGA;COSMIC;CCLE	8.575	Up-regulation
TK_Jak_JAK1_Y	Q99683	MAP3K5	P23458	JAK1	Y961	P968L	968	Missense	distal	7	no	9.213	9.837	EPSD	TCGA;COSMIC	8.575	Up-regulation
TK_Jak_JAK1_Y	P42224	STAT1	P23458	JAK1	Y701	E705K	705	Missense	distal	4	no	19.205	18.813	PhosphoSitePlus	TCGA;ICGC;COSMIC	8.575	Down-regulation
Atypical_TAF1_TAF1_ST	P52655	GTF2A1	P21675	TAF1	S280	T279I	279	Missense	proximal	-1	no	6.397	6.404	EPSD	TCGA;COSMIC	2.466	Up-regulation
Atypical_TAF1_TAF1_ST	P52655	GTF2A1	P21675	TAF1	S280	T279A	279	Missense	proximal	-1	no	6.397	6.396	EPSD	TCGA;COSMIC	2.466	Down-regulation
Atypical_TAF1_TAF1_ST	P52655	GTF2A1	P21675	TAF1	S281	T279I	279	Missense	proximal	-2	no	6.891	6.996	EPSD	TCGA;COSMIC	2.466	Up-regulation
Atypical_TAF1_TAF1_ST	P52655	GTF2A1	P21675	TAF1	S281	T279A	279	Missense	proximal	-2	no	6.891	6.847	EPSD	TCGA;COSMIC	2.466	Down-regulation
Atypical_TAF1_TAF1_ST	P52655	GTF2A1	P21675	TAF1	S316	D318Y	318	Missense	proximal	2	no	7.437	6.603	EPSD;PhosphoSitePlus	TCGA;COSMIC	2.466	Down-regulation
Atypical_TAF1_TAF1_ST	P52655	GTF2A1	P21675	TAF1	S316	E310K	310	Missense	distal	-6	no	7.437	7.471	EPSD;PhosphoSitePlus	TCGA;COSMIC	2.466	Up-regulation
Atypical_TAF1_TAF1_ST	P52655	GTF2A1	P21675	TAF1	S316	L314F	314	Missense	proximal	-2	no	7.437	7.301	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	2.466	Down-regulation
Atypical_TAF1_TAF1_ST	P52655	GTF2A1	P21675	TAF1	S321	Q326E	326	Missense	distal	5	no	7.637	7.424	PhosphoSitePlus;EPSD	TCGA;COSMIC	2.466	Down-regulation
Atypical_TAF1_TAF1_ST	P52655	GTF2A1	P21675	TAF1	S321	D318Y	318	Missense	distal	-3	no	7.637	7.321	PhosphoSitePlus;EPSD	TCGA;COSMIC	2.466	Down-regulation
Atypical_TAF1_TAF1_ST	P52655	GTF2A1	P21675	TAF1	S321	L314F	314	Missense	distal	-7	no	7.637	7.457	PhosphoSitePlus;EPSD	TCGA;ICGC;COSMIC	2.466	Down-regulation
Atypical_TAF1_TAF1_ST	Q15545	TAF7	P21675	TAF1	S171	R168Q	168	Missense	distal	-3	no	2.788	2.781	EPSD	TCGA;ICGC;COSMIC	2.466	Down-regulation
Atypical_TAF1_TAF1_ST	Q15545	TAF7	P21675	TAF1	S171	L169S	169	Missense	proximal	-2	no	2.788	2.499	EPSD	TCGA;ICGC;COSMIC	2.466	Down-regulation
Atypical_TAF1_TAF1_ST	Q15545	TAF7	P21675	TAF1	S171	K167N	167	Missense	distal	-4	no	2.788	2.463	EPSD	TCGA;ICGC	2.466	Loss
Atypical_TAF1_TAF1_ST	Q15545	TAF7	P21675	TAF1	S229	F223L	223	Missense	distal	-6	no	3.327	3.354	EPSD	TCGA;ICGC;COSMIC	2.466	Up-regulation
Atypical_TAF1_TAF1_ST	Q15545	TAF7	P21675	TAF1	S229	D225A	225	Missense	distal	-4	no	3.327	3.054	EPSD	TCGA;ICGC;COSMIC	2.466	Down-regulation
Atypical_TAF1_TAF1_ST	Q15545	TAF7	P21675	TAF1	S229	D234Y	234	Missense	distal	5	no	3.327	3.399	EPSD	TCGA	2.466	Up-regulation
Atypical_TAF1_TAF1_ST	Q15545	TAF7	P21675	TAF1	S229	S230N	230	Missense	proximal	1	no	3.327	2.771	EPSD	TCGA;ICGC;COSMIC	2.466	Down-regulation
Atypical_TAF1_TAF1_ST	Q15545	TAF7	P21675	TAF1	S229	F223C	223	Missense	distal	-6	no	3.327	3.343	EPSD	TCGA;ICGC;COSMIC	2.466	Up-regulation
Atypical_TAF1_TAF1_ST	Q15545	TAF7	P21675	TAF1	S264	E266K	266	Missense	proximal	2	no	7.120	6.327	PhosphoSitePlus	TCGA;ICGC;COSMIC	2.466	Down-regulation
Atypical_TAF1_TAF1_ST	P04637	TP53	P21675	TAF1	S46	D48N	48	Missense	proximal	2	no	3.420	2.336	EPSD	TCGA;ICGC;COSMIC;GDSC;CCLE	2.466	Loss
Atypical_TAF1_TAF1_ST	P04637	TP53	P21675	TAF1	T55	D57N	57	Missense	proximal	2	no	6.462	5.378	PhosphoSitePlus	TCGA;ICGC;COSMIC	2.466	Down-regulation
Atypical_TAF1_TAF1_ST	P04637	TP53	P21675	TAF1	T55	D48N	48	Missense	distal	-7	no	6.462	6.368	PhosphoSitePlus	TCGA;ICGC;COSMIC;GDSC;CCLE	2.466	Down-regulation
Atypical_TAF1_TAF1_ST	P04637	TP53	P21675	TAF1	T55	D61G	61	Missense	distal	6	no	6.462	4.380	PhosphoSitePlus	TCGA;ICGC;COSMIC	2.466	Down-regulation
Atypical_TAF1_TAF1_ST	P04637	TP53	P21675	TAF1	T125	Y126D	126	Missense	proximal	1	no	1.766	2.744	EPSD	TCGA;ICGC;COSMIC;GDSC	2.466	Gain
Atypical_TAF1_TAF1_ST	P04637	TP53	P21675	TAF1	S183	H179R	179	Missense	distal	-4	no	3.336	3.317	EPSD	TCGA;ICGC;COSMIC;GDSC;CCLE	2.466	Down-regulation
Atypical_TAF1_TAF1_ST	P04637	TP53	P21675	TAF1	S183	C176F	176	Missense	distal	-7	no	3.336	3.317	EPSD	TCGA;ICGC;COSMIC;GDSC;CCLE	2.466	Down-regulation
Atypical_TAF1_TAF1_ST	P04637	TP53	P21675	TAF1	S183	R181H	181	Missense	proximal	-2	no	3.336	3.237	EPSD	TCGA;ICGC;COSMIC;CCLE	2.466	Down-regulation
Atypical_TAF1_TAF1_ST	P04637	TP53	P21675	TAF1	S183	G187S	187	Missense	distal	4	no	3.336	3.023	EPSD	TCGA;ICGC;COSMIC	2.466	Down-regulation
Atypical_TAF1_TAF1_ST	P04637	TP53	P21675	TAF1	S183	H179Y	179	Missense	distal	-4	no	3.336	3.323	EPSD	TCGA;ICGC;COSMIC	2.466	Down-regulation
Atypical_TAF1_TAF1_ST	P04637	TP53	P21675	TAF1	S183	C176Y	176	Missense	distal	-7	no	3.336	3.174	EPSD	TCGA;ICGC;COSMIC;GDSC;CCLE	2.466	Down-regulation
Atypical_TAF1_TAF1_ST	P04637	TP53	P21675	TAF1	S183	P190L	190	Missense	distal	7	no	3.336	3.316	EPSD	TCGA;ICGC;COSMIC;CCLE	2.466	Down-regulation
Atypical_TAF1_TAF1_ST	P04637	TP53	P21675	TAF1	S183	P177S	177	Missense	distal	-6	no	3.336	3.319	EPSD	TCGA;ICGC;COSMIC	2.466	Down-regulation
Atypical_TAF1_TAF1_ST	P04637	TP53	P21675	TAF1	S183	H178Q	178	Missense	distal	-5	no	3.336	3.406	EPSD	TCGA;ICGC;COSMIC	2.466	Up-regulation
Atypical_TAF1_TAF1_ST	P04637	TP53	P21675	TAF1	S183	E180K	180	Missense	distal	-3	no	3.336	3.643	EPSD	TCGA;ICGC;COSMIC;CCLE	2.466	Up-regulation
Atypical_TAF1_TAF1_ST	P04637	TP53	P21675	TAF1	S183	C176S	176	Missense	distal	-7	no	3.336	3.172	EPSD	TCGA;ICGC;COSMIC;GDSC;CCLE	2.466	Down-regulation
Atypical_TAF1_TAF1_ST	P04637	TP53	P21675	TAF1	S183	H179N	179	Missense	distal	-4	no	3.336	3.371	EPSD	TCGA;ICGC;COSMIC	2.466	Up-regulation
Atypical_TAF1_TAF1_ST	P04637	TP53	P21675	TAF1	S183	H179P	179	Missense	distal	-4	no	3.336	3.594	EPSD	TCGA;ICGC;COSMIC	2.466	Up-regulation
Atypical_TAF1_TAF1_ST	P04637	TP53	P21675	TAF1	S183	H179L	179	Missense	distal	-4	no	3.336	3.263	EPSD	TCGA;ICGC;COSMIC	2.466	Down-regulation
Atypical_TAF1_TAF1_ST	P04637	TP53	P21675	TAF1	S183	H179D	179	Missense	distal	-4	no	3.336	3.731	EPSD	TCGA;ICGC;COSMIC;GDSC;CCLE	2.466	Up-regulation
Atypical_TAF1_TAF1_ST	P04637	TP53	P21675	TAF1	S183	P190R	190	Missense	distal	7	no	3.336	3.311	EPSD	TCGA;ICGC;COSMIC	2.466	Down-regulation
Atypical_TAF1_TAF1_ST	P04637	TP53	P21675	TAF1	S183	P177R	177	Missense	distal	-6	no	3.336	3.352	EPSD	TCGA;ICGC;COSMIC	2.466	Up-regulation
Atypical_TAF1_TAF1_ST	P04637	TP53	P21675	TAF1	S183	P177H	177	Missense	distal	-6	no	3.336	3.333	EPSD	TCGA;ICGC;COSMIC	2.466	Down-regulation
Atypical_TAF1_TAF1_ST	P04637	TP53	P21675	TAF1	S183	C176W	176	Missense	distal	-7	no	3.336	3.341	EPSD	TCGA;ICGC;COSMIC;GDSC;CCLE	2.466	Up-regulation
Atypical_TAF1_TAF1_ST	P04637	TP53	P21675	TAF1	S183	H179Q	179	Missense	distal	-4	no	3.336	3.431	EPSD	TCGA;ICGC;COSMIC;GDSC;CCLE	2.466	Up-regulation
Atypical_TAF1_TAF1_ST	P04637	TP53	P21675	TAF1	S183	P177T	177	Missense	distal	-6	no	3.336	3.341	EPSD	TCGA;ICGC;COSMIC;GDSC;CCLE	2.466	Up-regulation
Atypical_TAF1_TAF1_ST	P04637	TP53	P21675	TAF1	S183	R181P	181	Missense	proximal	-2	no	3.336	3.335	EPSD	TCGA;ICGC;COSMIC;CCLE	2.466	Down-regulation
Atypical_TAF1_TAF1_ST	P04637	TP53	P21675	TAF1	S183	C176R	176	Missense	distal	-7	no	3.336	3.325	EPSD	TCGA;ICGC;COSMIC	2.466	Down-regulation
Atypical_TAF1_TAF1_ST	P04637	TP53	P21675	TAF1	S183	R181C	181	Missense	proximal	-2	no	3.336	3.473	EPSD	TCGA;ICGC;COSMIC;GDSC;CCLE	2.466	Up-regulation
Atypical_TAF1_TAF1_ST	P04637	TP53	P21675	TAF1	S183	P177L	177	Missense	distal	-6	no	3.336	3.367	EPSD	TCGA;ICGC;COSMIC;GDSC;CCLE	2.466	Up-regulation
Atypical_TAF1_TAF1_ST	P04637	TP53	P21675	TAF1	S215	V216E	216	Missense	proximal	1	no	1.839	2.986	EPSD	TCGA;ICGC;COSMIC	2.466	Gain
Atypical_TAF1_TAF1_ST	P04637	TP53	P21675	TAF1	S313	K319N	319	Missense	distal	6	no	3.173	3.127	EPSD	TCGA;ICGC;COSMIC	2.466	Down-regulation
Atypical_TAF1_TAF1_ST	P04637	TP53	P21675	TAF1	S313	A307V	307	Missense	distal	-6	no	3.173	3.172	EPSD	TCGA;ICGC;COSMIC;GDSC	2.466	Down-regulation
Atypical_TAF1_TAF1_ST	P04637	TP53	P21675	TAF1	S313	K320E	320	Missense	distal	7	no	3.173	3.199	EPSD	TCGA;ICGC;COSMIC	2.466	Up-regulation
Atypical_TAF1_TAF1_ST	P04637	TP53	P21675	TAF1	S313	S315C	315	Missense	proximal	2	no	3.173	2.625	EPSD	TCGA;ICGC;COSMIC	2.466	Down-regulation
Atypical_TAF1_TAF1_ST	P04637	TP53	P21675	TAF1	S314	K320E	320	Missense	distal	6	no	1.978	3.355	EPSD	TCGA;ICGC;COSMIC	2.466	Gain
TK_Abl_ABL1_Y	P37840	SNCA	P00519	ABL1	Y39	E35K	35	Missense	distal	-4	no	8.108	5.441	PhosphoSitePlus;EPSD	TCGA;ICGC;COSMIC	7.039	Loss
TK_Abl_ABL1_Y	P37840	SNCA	P00519	ABL1	Y125	P120S	120	Missense	distal	-5	no	11.633	11.852	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	7.039	Up-regulation
TK_Abl_ABL1_Y	P37840	SNCA	P00519	ABL1	Y125	S129F	129	Missense	distal	4	no	11.633	11.331	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	7.039	Down-regulation
TK_Abl_ABL1_Y	P37840	SNCA	P00519	ABL1	Y136	E137K	137	Missense	proximal	1	no	8.117	7.577	EPSD	TCGA;ICGC;COSMIC	7.039	Down-regulation
TK_Abl_ABL1_Y	P37840	SNCA	P00519	ABL1	Y136	D135Y	135	Missense	proximal	-1	no	8.117	9.112	EPSD	TCGA;ICGC;COSMIC	7.039	Up-regulation
TK_Abl_ABL1_Y	P37840	SNCA	P00519	ABL1	Y136	S129F	129	Missense	distal	-7	no	8.117	7.638	EPSD	TCGA;ICGC;COSMIC	7.039	Down-regulation
TK_Abl_ABL1_Y	P46937	YAP1	P00519	ABL1	Y407	P413Q	413	Missense	distal	6	no	7.992	8.737	PhosphoSitePlus	TCGA;ICGC;COSMIC	7.039	Up-regulation
TK_Abl_ABL1_Y	O94875	SORBS2	P00519	ABL1	Y1007	P1013L	1013	Missense	distal	6	no	7.264	6.594	EPSD	TCGA;ICGC;COSMIC	7.039	Loss
TK_Abl_ABL1_Y	Q9UL17	TBX21	P00519	ABL1	Y125	A126V	126	Missense	proximal	1	no	10.001	8.984	EPSD	TCGA;ICGC;COSMIC	7.039	Down-regulation
TK_Abl_ABL1_Y	Q9UL17	TBX21	P00519	ABL1	Y125	A129V	129	Missense	distal	4	no	10.001	9.560	EPSD	TCGA;ICGC;COSMIC	7.039	Down-regulation
TK_Abl_ABL1_Y	Q9UL17	TBX21	P00519	ABL1	Y220	P226R	226	Missense	distal	6	no	10.447	10.339	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	7.039	Down-regulation
TK_Abl_ABL1_Y	Q9UL17	TBX21	P00519	ABL1	Y220	G216E	216	Missense	distal	-4	no	10.447	11.495	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	7.039	Up-regulation
TK_Abl_ABL1_Y	P04040	CAT	P00519	ABL1	Y231	G227R	227	Missense	distal	-4	no	9.490	9.293	PhosphoSitePlus;EPSD	TCGA;ICGC;COSMIC	7.039	Down-regulation
TK_Abl_ABL1_Y	P04040	CAT	P00519	ABL1	Y231	H235Y	235	Missense	distal	4	no	9.490	10.078	PhosphoSitePlus;EPSD	TCGA;ICGC;COSMIC	7.039	Up-regulation
TK_Abl_ABL1_Y	P04040	CAT	P00519	ABL1	Y386	P391L	391	Missense	distal	5	no	7.047	7.679	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	7.039	Up-regulation
TK_Abl_ABL1_Y	P04040	CAT	P00519	ABL1	Y386	R380C	380	Missense	distal	-6	no	7.047	6.837	EPSD;PhosphoSitePlus	TCGA;ICGC	7.039	Loss
TK_Abl_ABL1_Y	Q15746	MYLK	P00519	ABL1	Y104	E107K	107	Missense	distal	3	no	6.316	8.312	EPSD	TCGA;ICGC;COSMIC	7.039	Gain
TK_Abl_ABL1_Y	Q15746	MYLK	P00519	ABL1	Y464	G468D	468	Missense	distal	4	no	6.813	7.069	EPSD;PhosphoSitePlus	TCGA;ICGC;GDSC;CCLE	7.039	Gain
TK_Abl_ABL1_Y	Q15746	MYLK	P00519	ABL1	Y556	L549Q	549	Missense	distal	-7	no	9.861	10.443	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	7.039	Up-regulation
TK_Abl_ABL1_Y	Q15746	MYLK	P00519	ABL1	Y556	E562K	562	Missense	distal	6	no	9.861	10.221	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	7.039	Up-regulation
TK_Abl_ABL1_Y	Q15746	MYLK	P00519	ABL1	Y1449	T1456I	1456	Missense	distal	7	no	7.716	7.642	PhosphoSitePlus;EPSD	TCGA;ICGC	7.039	Down-regulation
TK_Abl_ABL1_Y	Q15746	MYLK	P00519	ABL1	Y1575	S1570L	1570	Missense	distal	-5	no	8.886	7.268	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	7.039	Down-regulation
TK_Abl_ABL1_Y	Q15746	MYLK	P00519	ABL1	Y1575	E1571K	1571	Missense	distal	-4	no	8.886	6.220	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	7.039	Loss
TK_Abl_ABL1_Y	Q15746	MYLK	P00519	ABL1	Y1635	G1639S	1639	Missense	distal	4	no	7.901	7.905	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC;GDSC	7.039	Up-regulation
TK_Abl_ABL1_Y	Q15746	MYLK	P00519	ABL1	Y1635	V1632L	1632	Missense	distal	-3	no	7.901	7.333	EPSD;PhosphoSitePlus	TCGA	7.039	Down-regulation
TK_Abl_ABL1_Y	Q15746	MYLK	P00519	ABL1	Y1635	A1641V	1641	Missense	distal	6	no	7.901	8.149	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	7.039	Up-regulation
TK_Abl_ABL1_Y	Q15746	MYLK	P00519	ABL1	Y1635	V1632A	1632	Missense	distal	-3	no	7.901	8.416	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	7.039	Up-regulation
TK_Abl_ABL1_Y	Q15746	MYLK	P00519	ABL1	Y1835	C1830S	1830	Missense	distal	-5	no	6.424	8.424	EPSD	TCGA;COSMIC	7.039	Gain
TK_Abl_ABL1_Y	O15350	TP73	P00519	ABL1	Y99	V93M	93	Missense	distal	-6	no	11.076	11.004	PhosphoSitePlus	TCGA;ICGC;COSMIC	7.039	Down-regulation
TK_Abl_ABL1_Y	O15350	TP73	P00519	ABL1	Y99	S103G	103	Missense	distal	4	no	11.076	11.072	PhosphoSitePlus	TCGA;ICGC;COSMIC	7.039	Down-regulation
TK_Abl_ABL1_Y	O15350	TP73	P00519	ABL1	Y99	T105I	105	Missense	distal	6	no	11.076	11.053	PhosphoSitePlus	TCGA;ICGC;COSMIC	7.039	Down-regulation
TK_Abl_ABL1_Y	O15350	TP73	P00519	ABL1	Y99	S97L	97	Missense	proximal	-2	no	11.076	10.098	PhosphoSitePlus	TCGA;ICGC;COSMIC	7.039	Down-regulation
TK_Abl_ABL1_Y	Q03135	CAV1	P00519	ABL1	Y14	G11A	11	Missense	distal	-3	no	13.796	14.450	PhosphoSitePlus	TCGA;ICGC;COSMIC	7.039	Up-regulation
TK_Abl_ABL1_Y	Q03135	CAV1	P00519	ABL1	Y14	E10K	10	Missense	distal	-4	no	13.796	11.130	PhosphoSitePlus	TCGA;ICGC;COSMIC	7.039	Down-regulation
TK_Abl_ABL1_Y	Q03135	CAV1	P00519	ABL1	Y14	E20K	20	Missense	distal	6	no	13.796	14.157	PhosphoSitePlus	TCGA;ICGC;COSMIC	7.039	Up-regulation
TK_Abl_ABL1_Y	Q03135	CAV1	P00519	ABL1	Y14	V7A	7	Missense	distal	-7	no	13.796	13.529	PhosphoSitePlus	TCGA;ICGC;COSMIC	7.039	Down-regulation
TK_Abl_ABL1_Y	Q03135	CAV1	P00519	ABL1	Y14	T15A	15	Missense	proximal	1	no	13.796	15.063	PhosphoSitePlus	TCGA;ICGC;COSMIC	7.039	Up-regulation
TK_Abl_ABL1_Y	Q03135	CAV1	P00519	ABL1	Y14	R19Q	19	Missense	distal	5	no	13.796	13.336	PhosphoSitePlus	TCGA;ICGC;COSMIC	7.039	Down-regulation
TK_Abl_ABL1_Y	Q03135	CAV1	P00519	ABL1	Y25	E20K	20	Missense	distal	-5	no	7.852	8.060	EPSD	TCGA;ICGC;COSMIC	7.039	Up-regulation
TK_Abl_ABL1_Y	Q03135	CAV1	P00519	ABL1	Y25	R19Q	19	Missense	distal	-6	no	7.852	7.789	EPSD	TCGA;ICGC;COSMIC	7.039	Down-regulation
TK_Abl_ABL1_Y	Q06609	RAD51	P00519	ABL1	Y54	H47N	47	Missense	distal	-7	no	7.756	8.655	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	7.039	Up-regulation
TK_Abl_ABL1_Y	Q06609	RAD51	P00519	ABL1	Y54	V49A	49	Missense	distal	-5	no	7.756	7.942	EPSD;PhosphoSitePlus	TCGA;ICGC	7.039	Up-regulation
TK_Abl_ABL1_Y	Q06609	RAD51	P00519	ABL1	Y54	K57N	57	Missense	distal	3	no	7.756	8.097	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	7.039	Up-regulation
TK_Abl_ABL1_Y	P55317	FOXA1	P00519	ABL1	Y459	A458T	458	Missense	proximal	-1	no	7.548	6.945	EPSD	TCGA	7.039	Loss
TK_Abl_ABL1_Y	P55317	FOXA1	P00519	ABL1	Y459	P452L	452	Missense	distal	-7	no	7.548	7.358	EPSD	TCGA;ICGC	7.039	Down-regulation
TK_Abl_ABL1_Y	P55317	FOXA1	P00519	ABL1	Y459	E456D	456	Missense	distal	-3	no	7.548	6.899	EPSD	TCGA;ICGC	7.039	Loss
TK_Abl_ABL1_Y	P55317	FOXA1	P00519	ABL1	Y460	A458T	458	Missense	proximal	-2	no	8.009	8.226	EPSD	TCGA	7.039	Up-regulation
TK_Abl_ABL1_Y	P55317	FOXA1	P00519	ABL1	Y460	E456D	456	Missense	distal	-4	no	8.009	6.723	EPSD	TCGA;ICGC	7.039	Loss
TK_Abl_ABL1_Y	P55317	FOXA1	P00519	ABL1	Y464	A458T	458	Missense	distal	-6	no	11.533	11.520	PhosphoSitePlus;EPSD	TCGA	7.039	Down-regulation
TK_Abl_ABL1_Y	P55317	FOXA1	P00519	ABL1	Y464	T471P	471	Missense	distal	7	no	11.533	11.508	PhosphoSitePlus;EPSD	TCGA;ICGC;COSMIC	7.039	Down-regulation
TK_Abl_ABL1_Y	P03372	ESR1	P00519	ABL1	Y52	Y52H	52	Missense	central	0	yes	9.828	0.000	PhosphoSitePlus;EPSD	TCGA;ICGC;COSMIC	7.039	Loss
TK_Abl_ABL1_Y	P03372	ESR1	P00519	ABL1	Y52	E56K	56	Missense	distal	4	no	9.828	9.453	PhosphoSitePlus;EPSD	TCGA;COSMIC	7.039	Down-regulation
TK_Abl_ABL1_Y	P03372	ESR1	P00519	ABL1	Y219	N217S	217	Missense	proximal	-2	no	9.788	9.902	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	7.039	Up-regulation
TK_Abl_ABL1_Y	P03372	ESR1	P00519	ABL1	Y219	D218N	218	Missense	proximal	-1	no	9.788	9.460	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	7.039	Down-regulation
TK_Abl_ABL1_Y	P03372	ESR1	P00519	ABL1	Y328	E330D	330	Missense	proximal	2	no	7.495	7.688	EPSD	TCGA;ICGC;COSMIC	7.039	Up-regulation
TK_Abl_ABL1_Y	Q13535	ATR	P00519	ABL1	Y291	L298R	298	Missense	distal	7	no	7.178	7.195	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	7.039	Up-regulation
TK_Abl_ABL1_Y	Q13535	ATR	P00519	ABL1	Y310	P304L	304	Missense	distal	-6	no	7.851	7.699	PhosphoSitePlus;EPSD	TCGA;ICGC;COSMIC	7.039	Down-regulation
TK_Abl_ABL1_Y	Q13535	ATR	P00519	ABL1	Y310	R311K	311	Missense	proximal	1	no	7.851	7.813	PhosphoSitePlus;EPSD	TCGA;ICGC	7.039	Down-regulation
TK_Abl_ABL1_Y	Q13535	ATR	P00519	ABL1	Y317	L318S	318	Missense	proximal	1	no	6.409	7.919	EPSD	TCGA;ICGC;COSMIC	7.039	Gain
TK_Abl_ABL1_Y	Q13535	ATR	P00519	ABL1	Y1479	I1478T	1478	Missense	proximal	-1	no	7.363	5.446	EPSD	TCGA;COSMIC	7.039	Loss
TK_Abl_ABL1_Y	Q13535	ATR	P00519	ABL1	Y1680	H1684D	1684	Missense	distal	4	no	6.856	7.625	EPSD	TCGA;ICGC;COSMIC	7.039	Gain
TK_Abl_ABL1_Y	P11274	BCR	P00519	ABL1	Y283	Y283C	283	Missense	central	0	yes	8.285	0.000	EPSD	TCGA;ICGC;COSMIC	7.039	Loss
TK_Abl_ABL1_Y	P11274	BCR	P00519	ABL1	Y283	Q277R	277	Missense	distal	-6	no	8.285	8.347	EPSD	TCGA;ICGC;COSMIC	7.039	Up-regulation
TK_Abl_ABL1_Y	P11274	BCR	P00519	ABL1	Y283	M287V	287	Missense	distal	4	no	8.285	8.461	EPSD	TCGA;ICGC;COSMIC	7.039	Up-regulation
TK_Abl_ABL1_Y	P11274	BCR	P00519	ABL1	Y360	D365N	365	Missense	distal	5	no	9.495	8.836	EPSD	TCGA;ICGC	7.039	Down-regulation
TK_Abl_ABL1_Y	P11274	BCR	P00519	ABL1	Y455	S459L	459	Missense	distal	4	no	8.418	8.300	EPSD	TCGA;ICGC;COSMIC;GDSC;CCLE	7.039	Down-regulation
TK_Abl_ABL1_Y	P11274	BCR	P00519	ABL1	Y554	H557R	557	Missense	distal	3	no	7.654	6.229	EPSD	TCGA;ICGC;COSMIC	7.039	Loss
TK_Abl_ABL1_Y	P11274	BCR	P00519	ABL1	Y554	E555V	555	Missense	proximal	1	no	7.654	7.743	EPSD	TCGA;ICGC;COSMIC	7.039	Up-regulation
TK_Abl_ABL1_Y	P11274	BCR	P00519	ABL1	Y644	T651M	651	Missense	distal	7	no	8.079	8.073	EPSD	TCGA;ICGC;COSMIC	7.039	Down-regulation
TK_Abl_ABL1_Y	P11274	BCR	P00519	ABL1	Y644	N637K	637	Missense	distal	-7	no	8.079	7.495	EPSD	TCGA;ICGC;COSMIC	7.039	Down-regulation
TK_Abl_ABL1_Y	P11274	BCR	P00519	ABL1	Y644	D648N	648	Missense	distal	4	no	8.079	8.121	EPSD	TCGA;ICGC;COSMIC	7.039	Up-regulation
TK_Abl_ABL1_Y	P19174	PLCG1	P00519	ABL1	Y162	D165V	165	Missense	distal	3	no	7.137	8.990	EPSD	TCGA;ICGC;COSMIC	7.039	Up-regulation
TK_Abl_ABL1_Y	P19174	PLCG1	P00519	ABL1	Y162	R158Q	158	Missense	distal	-4	no	7.137	6.896	EPSD	TCGA;ICGC;COSMIC	7.039	Loss
TK_Abl_ABL1_Y	P19174	PLCG1	P00519	ABL1	Y162	R168C	168	Missense	distal	6	no	7.137	6.428	EPSD	TCGA;ICGC;COSMIC	7.039	Loss
TK_Abl_ABL1_Y	P19174	PLCG1	P00519	ABL1	Y210	S205N	205	Missense	distal	-5	no	9.726	9.174	EPSD	TCGA;ICGC;COSMIC	7.039	Down-regulation
TK_Abl_ABL1_Y	P19174	PLCG1	P00519	ABL1	Y210	R204C	204	Missense	distal	-6	no	9.726	9.516	EPSD	TCGA;ICGC;COSMIC	7.039	Down-regulation
TK_Abl_ABL1_Y	P19174	PLCG1	P00519	ABL1	Y210	R204H	204	Missense	distal	-6	no	9.726	9.554	EPSD	TCGA;ICGC;COSMIC	7.039	Down-regulation
TK_Abl_ABL1_Y	P19174	PLCG1	P00519	ABL1	Y472	M479I	479	Missense	distal	7	no	10.069	10.001	EPSD	TCGA;ICGC;COSMIC	7.039	Down-regulation
TK_Abl_ABL1_Y	P19174	PLCG1	P00519	ABL1	Y518	K516N	516	Missense	proximal	-2	no	6.445	7.252	EPSD	TCGA	7.039	Gain
TK_Abl_ABL1_Y	P19174	PLCG1	P00519	ABL1	Y771	A767P	767	Missense	distal	-4	no	9.737	10.025	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	7.039	Up-regulation
TK_Abl_ABL1_Y	P19174	PLCG1	P00519	ABL1	Y771	R778C	778	Missense	distal	7	no	9.737	9.654	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC;GDSC;CCLE	7.039	Down-regulation
TK_Abl_ABL1_Y	P19174	PLCG1	P00519	ABL1	Y783	F782L	782	Missense	proximal	-1	no	8.857	9.644	EPSD	TCGA;ICGC;COSMIC	7.039	Up-regulation
TK_Abl_ABL1_Y	P19174	PLCG1	P00519	ABL1	Y783	P788H	788	Missense	distal	5	no	8.857	9.153	EPSD	TCGA;ICGC	7.039	Up-regulation
TK_Abl_ABL1_Y	P19174	PLCG1	P00519	ABL1	Y783	R778C	778	Missense	distal	-5	no	8.857	6.800	EPSD	TCGA;ICGC;COSMIC;GDSC;CCLE	7.039	Loss
TK_Abl_ABL1_Y	P19174	PLCG1	P00519	ABL1	Y977	Y977C	977	Missense	central	0	yes	7.677	0.000	EPSD	TCGA;ICGC;COSMIC	7.039	Loss
TK_Abl_ABL1_Y	P19174	PLCG1	P00519	ABL1	Y977	R978W	978	Missense	proximal	1	no	7.677	4.902	EPSD	TCGA;ICGC;COSMIC	7.039	Loss
TK_Abl_ABL1_Y	P19174	PLCG1	P00519	ABL1	Y977	S982F	982	Missense	distal	5	no	7.677	8.395	EPSD	TCGA;ICGC;COSMIC	7.039	Up-regulation
TK_Abl_ABL1_Y	P19174	PLCG1	P00519	ABL1	Y1003	Y1003S	1003	Missense	central	0	yes	7.294	0.000	PhosphoSitePlus;EPSD	TCGA;ICGC;COSMIC	7.039	Loss
TK_Abl_ABL1_Y	P19174	PLCG1	P00519	ABL1	Y1003	R1005Q	1005	Missense	proximal	2	no	7.294	7.743	PhosphoSitePlus;EPSD	TCGA;ICGC;COSMIC	7.039	Up-regulation
TK_Abl_ABL1_Y	P19174	PLCG1	P00519	ABL1	Y1003	R1010H	1010	Missense	distal	7	no	7.294	7.266	PhosphoSitePlus;EPSD	TCGA;ICGC;COSMIC	7.039	Down-regulation
TK_Abl_ABL1_Y	P19174	PLCG1	P00519	ABL1	Y1003	R1010L	1010	Missense	distal	7	no	7.294	7.278	PhosphoSitePlus;EPSD	TCGA;ICGC;COSMIC	7.039	Down-regulation
TK_Abl_ABL1_Y	P08581	MET	P00519	ABL1	Y291	L296P	296	Missense	distal	5	no	7.451	6.819	EPSD	TCGA;ICGC;COSMIC	7.039	Loss
TK_Abl_ABL1_Y	P08581	MET	P00519	ABL1	Y291	P295H	295	Missense	distal	4	no	7.451	6.655	EPSD	TCGA;ICGC	7.039	Loss
TK_Abl_ABL1_Y	P08581	MET	P00519	ABL1	Y291	L296M	296	Missense	distal	5	no	7.451	6.639	EPSD	TCGA;ICGC	7.039	Loss
TK_Abl_ABL1_Y	P08581	MET	P00519	ABL1	Y745	P742L	742	Missense	distal	-3	no	8.513	7.747	EPSD	TCGA;ICGC;COSMIC	7.039	Down-regulation
TK_Abl_ABL1_Y	P08581	MET	P00519	ABL1	Y745	S752Y	752	Missense	distal	7	no	8.513	8.476	EPSD	TCGA;ICGC;CCLE	7.039	Down-regulation
TK_Abl_ABL1_Y	P08581	MET	P00519	ABL1	Y745	K751I	751	Missense	distal	6	no	8.513	8.200	EPSD	TCGA;ICGC;COSMIC	7.039	Down-regulation
TK_Abl_ABL1_Y	P08581	MET	P00519	ABL1	Y1159	R1166Q	1166	Missense	distal	7	no	7.456	7.485	EPSD	TCGA;COSMIC;CCLE	7.039	Up-regulation
TK_Abl_ABL1_Y	Q06187	BTK	P00519	ABL1	Y551	D549N	549	Missense	proximal	-2	no	8.504	9.101	EPSD	TCGA;ICGC;COSMIC	7.039	Up-regulation
TK_Abl_ABL1_Y	Q6P1J9	CDC73	P00519	ABL1	Y315	T311A	311	Missense	distal	-4	no	7.368	7.717	PhosphoSitePlus;EPSD	TCGA;ICGC;COSMIC	7.039	Up-regulation
TK_Abl_ABL1_Y	Q6P1J9	CDC73	P00519	ABL1	Y315	H316L	316	Missense	proximal	1	no	7.368	7.270	PhosphoSitePlus;EPSD	TCGA;ICGC;COSMIC	7.039	Down-regulation
TK_Abl_ABL1_Y	Q6P1J9	CDC73	P00519	ABL1	Y315	K308E	308	Missense	distal	-7	no	7.368	7.127	PhosphoSitePlus;EPSD	TCGA;ICGC;COSMIC	7.039	Down-regulation
TK_Abl_ABL1_Y	Q6P1J9	CDC73	P00519	ABL1	Y315	M318I	318	Missense	distal	3	no	7.368	6.859	PhosphoSitePlus;EPSD	TCGA;ICGC;COSMIC	7.039	Loss
TK_Abl_ABL1_Y	P00533	EGFR	P00519	ABL1	Y113	E114K	114	Missense	proximal	1	no	7.303	6.762	EPSD	TCGA;ICGC;COSMIC	7.039	Loss
TK_Abl_ABL1_Y	P00533	EGFR	P00519	ABL1	Y113	R108K	108	Missense	distal	-5	no	7.303	7.195	EPSD	TCGA;ICGC;COSMIC;GDSC;CCLE	7.039	Down-regulation
TK_Abl_ABL1_Y	P00533	EGFR	P00519	ABL1	Y113	R108G	108	Missense	distal	-5	no	7.303	6.897	EPSD	TCGA;ICGC;COSMIC	7.039	Loss
TK_Abl_ABL1_Y	P00533	EGFR	P00519	ABL1	Y113	S116F	116	Missense	distal	3	no	7.303	8.528	EPSD	TCGA;ICGC;COSMIC	7.039	Up-regulation
TK_Abl_ABL1_Y	P00533	EGFR	P00519	ABL1	Y998	A1000V	1000	Missense	proximal	2	no	7.230	6.227	EPSD	TCGA;COSMIC	7.039	Loss
TK_Abl_ABL1_Y	P00533	EGFR	P00519	ABL1	Y998	F997V	997	Missense	proximal	-1	no	7.230	7.710	EPSD	TCGA;COSMIC	7.039	Up-regulation
TK_Abl_ABL1_Y	P00533	EGFR	P00519	ABL1	Y1016	P1019L	1019	Missense	distal	3	no	10.060	7.483	PhosphoSitePlus;EPSD	TCGA;COSMIC	7.039	Down-regulation
TK_Abl_ABL1_Y	P00533	EGFR	P00519	ABL1	Y1016	D1009N	1009	Missense	distal	-7	no	10.060	10.613	PhosphoSitePlus;EPSD	TCGA;COSMIC	7.039	Up-regulation
TK_Abl_ABL1_Y	P00533	EGFR	P00519	ABL1	Y1197	A1201V	1201	Missense	distal	4	no	9.785	9.344	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	7.039	Down-regulation
TK_Abl_ABL1_Y	P00533	EGFR	P00519	ABL1	Y1197	A1195T	1195	Missense	proximal	-2	no	9.785	10.001	EPSD;PhosphoSitePlus	TCGA;ICGC	7.039	Up-regulation
TK_Abl_ABL1_Y	P42684	ABL2	P00519	ABL1	Y299	Q298L	298	Missense	proximal	-1	no	5.939	7.094	EPSD	TCGA;COSMIC	7.039	Gain
TK_Abl_ABL1_Y	P42684	ABL2	P00519	ABL1	Y366	M364I	364	Missense	proximal	-2	no	7.798	7.787	EPSD	TCGA;COSMIC	7.039	Down-regulation
TK_Abl_ABL1_Y	P42684	ABL2	P00519	ABL1	Y439	A443T	443	Missense	distal	4	no	7.103	6.886	EPSD	TCGA;COSMIC;CCLE	7.039	Loss
TK_Abl_ABL1_Y	P53350	PLK1	P00519	ABL1	Y217	G213V	213	Missense	distal	-4	no	9.779	9.475	PhosphoSitePlus;EPSD	TCGA;ICGC	7.039	Down-regulation
TK_Abl_ABL1_Y	P53350	PLK1	P00519	ABL1	Y268	I263M	263	Missense	distal	-5	no	6.663	7.331	EPSD	TCGA;ICGC;COSMIC	7.039	Gain
TK_Abl_ABL1_Y	Q9C0H9	SRCIN1	P00519	ABL1	Y155	R158K	158	Missense	distal	3	no	8.649	10.121	EPSD	TCGA	7.039	Up-regulation
TK_Abl_ABL1_Y	Q13573	SNW1	P00519	ABL1	Y98	I101V	101	Missense	distal	3	no	6.903	8.421	EPSD	TCGA;ICGC;COSMIC	7.039	Gain
TK_Abl_ABL1_Y	Q13573	SNW1	P00519	ABL1	Y292	R296W	296	Missense	distal	4	no	7.093	6.444	PhosphoSitePlus;EPSD	TCGA;ICGC	7.039	Loss
TK_Abl_ABL1_Y	Q13573	SNW1	P00519	ABL1	Y292	R296Q	296	Missense	distal	4	no	7.093	6.540	PhosphoSitePlus;EPSD	TCGA;ICGC	7.039	Loss
TK_Abl_ABL1_Y	Q13573	SNW1	P00519	ABL1	Y430	E428K	428	Missense	proximal	-2	no	7.489	6.817	EPSD;PhosphoSitePlus	TCGA;COSMIC	7.039	Loss
TK_Abl_ABL1_Y	Q13573	SNW1	P00519	ABL1	Y433	E428K	428	Missense	distal	-5	no	8.545	8.753	EPSD;PhosphoSitePlus	TCGA;COSMIC	7.039	Up-regulation
TK_Abl_ABL1_Y	Q6ZUJ8	PIK3AP1	P00519	ABL1	Y513	L506V	506	Missense	distal	-7	no	9.468	9.955	EPSD;PhosphoSitePlus	TCGA	7.039	Up-regulation
TK_Abl_ABL1_Y	Q6ZUJ8	PIK3AP1	P00519	ABL1	Y513	T515M	515	Missense	proximal	2	no	9.468	9.200	EPSD;PhosphoSitePlus	TCGA	7.039	Down-regulation
TK_Abl_ABL1_Y	Q6ZUJ8	PIK3AP1	P00519	ABL1	Y513	E509K	509	Missense	distal	-4	no	9.468	6.802	EPSD;PhosphoSitePlus	TCGA;COSMIC	7.039	Loss
TK_Abl_ABL1_Y	Q6ZUJ8	PIK3AP1	P00519	ABL1	Y513	H514Y	514	Missense	proximal	1	no	9.468	11.071	EPSD;PhosphoSitePlus	TCGA;COSMIC	7.039	Up-regulation
TK_Abl_ABL1_Y	Q6ZUJ8	PIK3AP1	P00519	ABL1	Y513	D519N	519	Missense	distal	6	no	9.468	10.074	EPSD;PhosphoSitePlus	TCGA;COSMIC	7.039	Up-regulation
TK_Abl_ABL1_Y	Q6ZUJ8	PIK3AP1	P00519	ABL1	Y513	L506I	506	Missense	distal	-7	no	9.468	9.416	EPSD;PhosphoSitePlus	TCGA;COSMIC	7.039	Down-regulation
TK_Abl_ABL1_Y	Q6ZUJ8	PIK3AP1	P00519	ABL1	Y553	F555C	555	Missense	proximal	2	no	7.187	7.244	EPSD;PhosphoSitePlus	TCGA;COSMIC	7.039	Up-regulation
TK_Abl_ABL1_Y	Q6ZUJ8	PIK3AP1	P00519	ABL1	Y570	R565Q	565	Missense	distal	-5	no	10.002	9.996	PhosphoSitePlus;EPSD	TCGA	7.039	Down-regulation
TK_Abl_ABL1_Y	Q6ZUJ8	PIK3AP1	P00519	ABL1	Y570	S572F	572	Missense	proximal	2	no	10.002	9.106	PhosphoSitePlus;EPSD	TCGA;COSMIC	7.039	Down-regulation
TK_Abl_ABL1_Y	Q6ZUJ8	PIK3AP1	P00519	ABL1	Y570	S573P	573	Missense	distal	3	no	10.002	13.137	PhosphoSitePlus;EPSD	TCGA;COSMIC	7.039	Up-regulation
TK_Abl_ABL1_Y	Q6ZUJ8	PIK3AP1	P00519	ABL1	Y570	F569L	569	Missense	proximal	-1	no	10.002	10.789	PhosphoSitePlus;EPSD	TCGA;COSMIC	7.039	Up-regulation
TK_Abl_ABL1_Y	Q6ZUJ8	PIK3AP1	P00519	ABL1	Y570	R565W	565	Missense	distal	-5	no	10.002	7.469	PhosphoSitePlus;EPSD	TCGA;COSMIC	7.039	Down-regulation
TK_Abl_ABL1_Y	Q6ZUJ8	PIK3AP1	P00519	ABL1	Y594	S592N	592	Missense	proximal	-2	no	10.425	10.311	EPSD;PhosphoSitePlus	TCGA;COSMIC	7.039	Down-regulation
TK_Abl_ABL1_Y	Q6ZUJ8	PIK3AP1	P00519	ABL1	Y594	R588K	588	Missense	distal	-6	no	10.425	10.208	EPSD;PhosphoSitePlus	TCGA;COSMIC	7.039	Down-regulation
TK_Abl_ABL1_Y	Q6ZUJ8	PIK3AP1	P00519	ABL1	Y594	M600I	600	Missense	distal	6	no	10.425	10.360	EPSD;PhosphoSitePlus	TCGA;COSMIC	7.039	Down-regulation
TK_Abl_ABL1_Y	Q6ZUJ8	PIK3AP1	P00519	ABL1	Y594	G599R	599	Missense	distal	5	no	10.425	10.072	EPSD;PhosphoSitePlus	TCGA;COSMIC	7.039	Down-regulation
TK_Abl_ABL1_Y	Q6ZUJ8	PIK3AP1	P00519	ABL1	Y594	D587G	587	Missense	distal	-7	no	10.425	10.167	EPSD;PhosphoSitePlus	TCGA	7.039	Down-regulation
TK_Abl_ABL1_Y	Q6ZUJ8	PIK3AP1	P00519	ABL1	Y694	G697C	697	Missense	distal	3	no	9.720	10.553	EPSD;PhosphoSitePlus	TCGA;COSMIC	7.039	Up-regulation
TK_Abl_ABL1_Y	Q6ZUJ8	PIK3AP1	P00519	ABL1	Y694	E690K	690	Missense	distal	-4	no	9.720	7.054	EPSD;PhosphoSitePlus	TCGA;COSMIC	7.039	Down-regulation
TK_Abl_ABL1_Y	P01112	HRAS	P00519	ABL1	Y40	D33N	33	Missense	distal	-7	no	6.569	7.122	EPSD	TCGA;ICGC;COSMIC	7.039	Gain
TK_Abl_ABL1_Y	P01112	HRAS	P00519	ABL1	Y96	E91K	91	Missense	distal	-5	no	7.473	7.682	EPSD	TCGA;ICGC;COSMIC	7.039	Up-regulation
TK_Abl_ABL1_Y	P01112	HRAS	P00519	ABL1	Y96	F90C	90	Missense	distal	-6	no	7.473	7.535	EPSD	TCGA;ICGC;COSMIC	7.039	Up-regulation
TK_Abl_ABL1_Y	P01112	HRAS	P00519	ABL1	Y137	A130T	130	Missense	distal	-7	no	7.057	7.404	PhosphoSitePlus	TCGA;ICGC;COSMIC	7.039	Up-regulation
TK_Abl_ABL1_Y	P01112	HRAS	P00519	ABL1	Y137	R135Q	135	Missense	proximal	-2	no	7.057	8.148	PhosphoSitePlus	TCGA;ICGC;COSMIC	7.039	Up-regulation
TK_Abl_ABL1_Y	P01112	HRAS	P00519	ABL1	Y137	A134T	134	Missense	distal	-3	no	7.057	6.395	PhosphoSitePlus	TCGA;ICGC;COSMIC	7.039	Loss
TK_Abl_ABL1_Y	P01112	HRAS	P00519	ABL1	Y137	E143K	143	Missense	distal	6	no	7.057	7.418	PhosphoSitePlus	TCGA;ICGC;COSMIC	7.039	Up-regulation
TK_Abl_ABL1_Y	O15151	MDM4	P00519	ABL1	Y55	Y59C	59	Missense	distal	4	no	9.089	9.198	PhosphoSitePlus;EPSD	TCGA;ICGC;COSMIC	7.039	Up-regulation
TK_Abl_ABL1_Y	O15151	MDM4	P00519	ABL1	Y99	D100N	100	Missense	proximal	1	no	7.822	7.522	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	7.039	Down-regulation
TK_Abl_ABL1_Y	P09619	PDGFRB	P00519	ABL1	Y589	E594G	594	Missense	distal	5	no	6.435	7.144	EPSD	TCGA;ICGC;COSMIC	7.039	Gain
TK_Abl_ABL1_Y	P09619	PDGFRB	P00519	ABL1	Y589	D590A	590	Missense	proximal	1	no	6.435	7.110	EPSD	TCGA;ICGC;COSMIC	7.039	Gain
TK_Abl_ABL1_Y	P09619	PDGFRB	P00519	ABL1	Y686	G687E	687	Missense	proximal	1	no	7.265	7.706	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	7.039	Up-regulation
TK_Abl_ABL1_Y	P09619	PDGFRB	P00519	ABL1	Y686	R685C	685	Missense	proximal	-1	no	7.265	9.219	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC;GDSC	7.039	Up-regulation
TK_Abl_ABL1_Y	P09619	PDGFRB	P00519	ABL1	Y686	G687R	687	Missense	proximal	1	no	7.265	7.204	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	7.039	Down-regulation
TK_Abl_ABL1_Y	P09619	PDGFRB	P00519	ABL1	Y716	R709L	709	Missense	distal	-7	no	7.053	6.816	EPSD	TCGA;ICGC;COSMIC	7.039	Loss
TK_Abl_ABL1_Y	P09619	PDGFRB	P00519	ABL1	Y716	P711H	711	Missense	distal	-5	no	7.053	5.560	EPSD	TCGA;ICGC;COSMIC	7.039	Loss
TK_Abl_ABL1_Y	P09619	PDGFRB	P00519	ABL1	Y716	A719V	719	Missense	distal	3	no	7.053	9.234	EPSD	TCGA;ICGC;COSMIC	7.039	Up-regulation
TK_Abl_ABL1_Y	P09619	PDGFRB	P00519	ABL1	Y751	Y751C	751	Missense	central	0	yes	7.940	0.000	EPSD	TCGA;ICGC;COSMIC	7.039	Loss
TK_Abl_ABL1_Y	P09619	PDGFRB	P00519	ABL1	Y771	D776N	776	Missense	distal	5	no	8.867	8.208	EPSD	TCGA;ICGC;COSMIC	7.039	Down-regulation
TK_Abl_ABL1_Y	P09619	PDGFRB	P00519	ABL1	Y771	Y778C	778	Missense	distal	7	no	8.867	8.835	EPSD	TCGA;ICGC;COSMIC	7.039	Down-regulation
TK_Abl_ABL1_Y	P09619	PDGFRB	P00519	ABL1	Y934	M937T	937	Missense	distal	3	no	8.950	8.333	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	7.039	Down-regulation
TK_Abl_ABL1_Y	P09619	PDGFRB	P00519	ABL1	Y934	C940Y	940	Missense	distal	6	no	8.950	9.498	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	7.039	Up-regulation
TK_Abl_ABL1_Y	P09619	PDGFRB	P00519	ABL1	Y970	K968N	968	Missense	proximal	-2	no	7.900	8.706	PhosphoSitePlus;EPSD	TCGA;ICGC;COSMIC	7.039	Up-regulation
TK_Abl_ABL1_Y	P09619	PDGFRB	P00519	ABL1	Y970	Q971K	971	Missense	proximal	1	no	7.900	7.596	PhosphoSitePlus;EPSD	TCGA;ICGC;COSMIC	7.039	Down-regulation
TK_Abl_ABL1_Y	P09619	PDGFRB	P00519	ABL1	Y1009	V1012M	1012	Missense	distal	3	no	8.739	7.731	EPSD	TCGA;ICGC;COSMIC	7.039	Down-regulation
TK_Abl_ABL1_Y	P09619	PDGFRB	P00519	ABL1	Y1009	V1012L	1012	Missense	distal	3	no	8.739	8.083	EPSD	TCGA;ICGC;COSMIC	7.039	Down-regulation
TK_Abl_ABL1_Y	P09619	PDGFRB	P00519	ABL1	Y1009	D1003N	1003	Missense	distal	-6	no	8.739	8.732	EPSD	TCGA;ICGC;COSMIC	7.039	Down-regulation
TK_Abl_ABL1_Y	P09619	PDGFRB	P00519	ABL1	Y1009	T1004I	1004	Missense	distal	-5	no	8.739	6.654	EPSD	TCGA;ICGC;COSMIC	7.039	Loss
TK_Abl_ABL1_Y	P09619	PDGFRB	P00519	ABL1	Y1009	V1007I	1007	Missense	proximal	-2	no	8.739	8.001	EPSD	TCGA;ICGC;COSMIC	7.039	Down-regulation
TK_Abl_ABL1_Y	P09619	PDGFRB	P00519	ABL1	Y1009	T1010A	1010	Missense	proximal	1	no	8.739	10.006	EPSD	TCGA;ICGC	7.039	Up-regulation
TK_Abl_ABL1_Y	P09619	PDGFRB	P00519	ABL1	Y1021	D1018E	1018	Missense	distal	-3	no	7.377	8.026	EPSD	TCGA;ICGC;COSMIC	7.039	Up-regulation
TK_Abl_ABL1_Y	Q14247	CTTN	P00519	ABL1	Y104	G101S	101	Missense	distal	-3	no	6.946	7.173	EPSD	TCGA;ICGC;COSMIC	7.039	Gain
TK_Abl_ABL1_Y	Q14247	CTTN	P00519	ABL1	Y178	D177E	177	Missense	proximal	-1	no	6.685	7.366	EPSD	TCGA;ICGC;COSMIC	7.039	Gain
TK_Abl_ABL1_Y	Q14247	CTTN	P00519	ABL1	Y178	K171N	171	Missense	distal	-7	no	6.685	7.270	EPSD	TCGA;ICGC;COSMIC	7.039	Gain
TK_Abl_ABL1_Y	Q9H3D4	TP63	P00519	ABL1	Y149	P152H	152	Missense	distal	3	no	11.962	8.745	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	7.039	Down-regulation
TK_Abl_ABL1_Y	Q9H3D4	TP63	P00519	ABL1	Y149	S142C	142	Missense	distal	-7	no	11.962	11.626	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	7.039	Down-regulation
TK_Abl_ABL1_Y	Q9H3D4	TP63	P00519	ABL1	Y149	A145V	145	Missense	distal	-4	no	11.962	12.184	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	7.039	Up-regulation
TK_Abl_ABL1_Y	Q9H3D4	TP63	P00519	ABL1	Y149	P148A	148	Missense	proximal	-1	no	11.962	11.997	EPSD;PhosphoSitePlus	TCGA;ICGC	7.039	Up-regulation
TK_Abl_ABL1_Y	Q9H3D4	TP63	P00519	ABL1	Y149	S153R	153	Missense	distal	4	no	11.962	12.244	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	7.039	Up-regulation
TK_Abl_ABL1_Y	Q9H3D4	TP63	P00519	ABL1	Y149	A150T	150	Missense	proximal	1	no	11.962	10.695	EPSD;PhosphoSitePlus	TCGA;COSMIC	7.039	Down-regulation
TK_Abl_ABL1_Y	Q9H3D4	TP63	P00519	ABL1	Y149	S142N	142	Missense	distal	-7	no	11.962	12.629	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	7.039	Up-regulation
TK_Abl_ABL1_Y	Q9H3D4	TP63	P00519	ABL1	Y290	Q294H	294	Missense	distal	4	no	8.252	8.007	EPSD;PhosphoSitePlus	TCGA;ICGC	7.039	Down-regulation
TK_Abl_ABL1_Y	Q9Y6Q9	NCOA3	P00519	ABL1	Y417	S413N	413	Missense	distal	-4	no	6.492	7.107	EPSD	TCGA;COSMIC	7.039	Gain
TK_Abl_ABL1_Y	Q9Y6Q9	NCOA3	P00519	ABL1	Y1357	A1353S	1353	Missense	distal	-4	no	8.959	9.009	PhosphoSitePlus	TCGA;COSMIC	7.039	Up-regulation
TK_Abl_ABL1_Y	Q9Y6Q9	NCOA3	P00519	ABL1	Y1357	E1361D	1361	Missense	distal	4	no	8.959	8.832	PhosphoSitePlus	TCGA;ICGC;COSMIC	7.039	Down-regulation
TK_Abl_ABL1_Y	P46108	CRK	P00519	ABL1	Y239	A240S	240	Missense	proximal	1	no	10.694	9.378	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	7.039	Down-regulation
TK_Abl_ABL1_Y	P46108	CRK	P00519	ABL1	Y239	R241G	241	Missense	proximal	2	no	10.694	10.754	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	7.039	Up-regulation
TK_Abl_ABL1_Y	Q14498	RBM39	P00519	ABL1	Y95	S100C	100	Missense	distal	5	no	8.709	9.487	PhosphoSitePlus;EPSD	TCGA;ICGC;COSMIC	7.039	Up-regulation
TK_Abl_ABL1_Y	Q14498	RBM39	P00519	ABL1	Y95	S100F	100	Missense	distal	5	no	8.709	9.426	PhosphoSitePlus;EPSD	TCGA;ICGC;COSMIC	7.039	Up-regulation
TK_Abl_ABL1_Y	Q14498	RBM39	P00519	ABL1	Y95	R94H	94	Missense	proximal	-1	no	8.709	10.476	PhosphoSitePlus;EPSD	TCGA;ICGC;COSMIC;CCLE	7.039	Up-regulation
TK_Abl_ABL1_Y	Q14498	RBM39	P00519	ABL1	Y99	S100C	100	Missense	proximal	1	no	11.761	10.697	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	7.039	Down-regulation
TK_Abl_ABL1_Y	Q14498	RBM39	P00519	ABL1	Y99	S100F	100	Missense	proximal	1	no	11.761	9.461	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	7.039	Down-regulation
TK_Abl_ABL1_Y	Q14498	RBM39	P00519	ABL1	Y99	R94H	94	Missense	distal	-5	no	11.761	9.992	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC;CCLE	7.039	Down-regulation
TK_Abl_ABL1_Y	P50402	EMD	P00519	ABL1	Y74	E80Q	80	Missense	distal	6	no	6.161	7.044	EPSD	TCGA;ICGC;COSMIC	7.039	Gain
TK_Abl_ABL1_Y	P50402	EMD	P00519	ABL1	Y155	R157Q	157	Missense	proximal	2	no	8.230	8.679	EPSD	TCGA;ICGC;COSMIC	7.039	Up-regulation
TK_Abl_ABL1_Y	P50402	EMD	P00519	ABL1	Y155	R157W	157	Missense	proximal	2	no	8.230	6.866	EPSD	TCGA;ICGC;COSMIC	7.039	Loss
TK_Abl_ABL1_Y	P16333	NCK1	P00519	ABL1	Y105	Y105C	105	Missense	central	0	yes	9.116	0.000	PhosphoSitePlus	TCGA;COSMIC	7.039	Loss
TK_Abl_ABL1_Y	P16333	NCK1	P00519	ABL1	Y105	R103H	103	Missense	proximal	-2	no	9.116	9.567	PhosphoSitePlus	TCGA;COSMIC	7.039	Up-regulation
TK_Abl_ABL1_Y	P16333	NCK1	P00519	ABL1	Y105	A111T	111	Missense	distal	6	no	9.116	9.124	PhosphoSitePlus	TCGA;GDSC;CCLE	7.039	Up-regulation
TK_Abl_ABL1_Y	P16333	NCK1	P00519	ABL1	Y105	D106A	106	Missense	proximal	1	no	9.116	9.791	PhosphoSitePlus	TCGA;COSMIC	7.039	Up-regulation
TK_Abl_ABL1_Y	P16333	NCK1	P00519	ABL1	Y268	I269T	269	Missense	proximal	1	no	6.821	7.357	EPSD	TCGA;COSMIC	7.039	Gain
TK_Abl_ABL1_Y	P43351	RAD52	P00519	ABL1	Y104	F103L	103	Missense	proximal	-1	no	8.111	8.898	PhosphoSitePlus	TCGA;ICGC;COSMIC	7.039	Up-regulation
TK_Abl_ABL1_Y	P43351	RAD52	P00519	ABL1	Y205	M212I	212	Missense	distal	7	no	10.511	10.443	EPSD	TCGA;ICGC;COSMIC	7.039	Down-regulation
TK_Abl_ABL1_Y	P43351	RAD52	P00519	ABL1	Y205	N206T	206	Missense	proximal	1	no	10.511	10.219	EPSD	TCGA;ICGC;COSMIC	7.039	Down-regulation
TK_Abl_ABL1_Y	Q9Y6N7	ROBO1	P00519	ABL1	Y307	R306I	306	Missense	proximal	-1	no	4.388	7.550	EPSD	TCGA;COSMIC	7.039	Gain
TK_Abl_ABL1_Y	Q9Y6N7	ROBO1	P00519	ABL1	Y1038	D1040H	1040	Missense	proximal	2	no	10.246	10.283	EPSD;PhosphoSitePlus	TCGA;COSMIC	7.039	Up-regulation
TK_Abl_ABL1_Y	Q9Y6N7	ROBO1	P00519	ABL1	Y1114	N1120S	1120	Missense	distal	6	no	8.926	8.633	PhosphoSitePlus;EPSD	TCGA;COSMIC	7.039	Down-regulation
TK_Abl_ABL1_Y	P04083	ANXA1	P00519	ABL1	Y21	S27L	27	Missense	distal	6	no	9.028	8.331	PhosphoSitePlus	TCGA;ICGC;COSMIC	7.039	Down-regulation
TK_Abl_ABL1_Y	P04083	ANXA1	P00519	ABL1	Y21	E17K	17	Missense	distal	-4	no	9.028	6.362	PhosphoSitePlus	TCGA;ICGC;COSMIC	7.039	Loss
TK_Abl_ABL1_Y	P04083	ANXA1	P00519	ABL1	Y207	D200N	200	Missense	distal	-7	no	7.140	7.693	EPSD	TCGA;ICGC;COSMIC	7.039	Up-regulation
TK_Abl_ABL1_Y	P04083	ANXA1	P00519	ABL1	Y207	D202N	202	Missense	distal	-5	no	7.140	6.906	EPSD	TCGA;ICGC;COSMIC	7.039	Loss
TK_Abl_ABL1_Y	P04083	ANXA1	P00519	ABL1	Y207	R212K	212	Missense	distal	5	no	7.140	7.478	EPSD	TCGA;ICGC;COSMIC	7.039	Up-regulation
TK_Abl_ABL1_Y	P04083	ANXA1	P00519	ABL1	Y207	G210R	210	Missense	distal	3	no	7.140	7.065	EPSD	TCGA;ICGC	7.039	Down-regulation
TK_Abl_ABL1_Y	P49023	PXN	P00519	ABL1	Y31	E27G	27	Missense	distal	-4	no	13.462	12.415	EPSD;PhosphoSitePlus	TCGA	7.039	Down-regulation
TK_Abl_ABL1_Y	P49023	PXN	P00519	ABL1	Y118	Q124H	124	Missense	distal	6	no	10.240	9.373	PhosphoSitePlus;EPSD	TCGA;COSMIC	7.039	Down-regulation
TK_Abl_ABL1_Y	P49023	PXN	P00519	ABL1	Y181	S188N	188	Missense	distal	7	no	7.226	7.241	EPSD	TCGA	7.039	Up-regulation
TK_Abl_ABL1_Y	P46109	CRKL	P00519	ABL1	Y15	R21C	21	Missense	distal	6	no	7.956	7.247	EPSD	TCGA;ICGC;COSMIC	7.039	Down-regulation
TK_Abl_ABL1_Y	P46109	CRKL	P00519	ABL1	Y15	A13P	13	Missense	proximal	-2	no	7.956	8.216	EPSD	TCGA;ICGC;COSMIC	7.039	Up-regulation
TK_Abl_ABL1_Y	P46109	CRKL	P00519	ABL1	Y15	S20F	20	Missense	distal	5	no	7.956	8.674	EPSD	TCGA;ICGC;COSMIC	7.039	Up-regulation
TK_Abl_ABL1_Y	P46109	CRKL	P00519	ABL1	Y105	A102V	102	Missense	distal	-3	no	7.660	7.145	EPSD	TCGA;ICGC;COSMIC	7.039	Down-regulation
TK_Abl_ABL1_Y	P46109	CRKL	P00519	ABL1	Y105	I99M	99	Missense	distal	-6	no	7.660	7.568	EPSD	TCGA;ICGC;COSMIC	7.039	Down-regulation
TK_Abl_ABL1_Y	P46109	CRKL	P00519	ABL1	Y132	L131V	131	Missense	proximal	-1	no	8.338	8.030	EPSD	TCGA;ICGC;COSMIC	7.039	Down-regulation
TK_Abl_ABL1_Y	P46109	CRKL	P00519	ABL1	Y132	D138Y	138	Missense	distal	6	no	8.338	8.351	EPSD	TCGA;ICGC;COSMIC	7.039	Up-regulation
TK_Abl_ABL1_Y	P46109	CRKL	P00519	ABL1	Y132	L125M	125	Missense	distal	-7	no	8.338	8.756	EPSD	TCGA;ICGC;COSMIC	7.039	Up-regulation
TK_Abl_ABL1_Y	P46109	CRKL	P00519	ABL1	Y132	L125P	125	Missense	distal	-7	no	8.338	8.528	EPSD	TCGA;ICGC;COSMIC	7.039	Up-regulation
TK_Abl_ABL1_Y	P46109	CRKL	P00519	ABL1	Y177	V178A	178	Missense	proximal	1	no	7.588	8.605	EPSD	TCGA;ICGC	7.039	Up-regulation
TK_Abl_ABL1_Y	P46109	CRKL	P00519	ABL1	Y198	H205R	205	Missense	distal	7	no	9.597	9.625	EPSD	TCGA;ICGC;COSMIC	7.039	Up-regulation
TK_Abl_ABL1_Y	P46109	CRKL	P00519	ABL1	Y198	S195F	195	Missense	distal	-3	no	9.597	8.173	EPSD	TCGA;ICGC;COSMIC	7.039	Down-regulation
TK_Abl_ABL1_Y	P46109	CRKL	P00519	ABL1	Y207	H205R	205	Missense	proximal	-2	no	8.825	8.374	PhosphoSitePlus	TCGA;ICGC;COSMIC	7.039	Down-regulation
TK_Abl_ABL1_Y	P46109	CRKL	P00519	ABL1	Y207	A206T	206	Missense	proximal	-1	no	8.825	8.223	PhosphoSitePlus	TCGA;ICGC	7.039	Down-regulation
TK_Abl_ABL1_Y	P46109	CRKL	P00519	ABL1	Y207	Q211E	211	Missense	distal	4	no	8.825	9.476	PhosphoSitePlus	TCGA;ICGC;COSMIC	7.039	Up-regulation
TK_Abl_ABL1_Y	P46109	CRKL	P00519	ABL1	Y207	Q211H	211	Missense	distal	4	no	8.825	8.581	PhosphoSitePlus	TCGA;ICGC	7.039	Down-regulation
TK_Abl_ABL1_Y	P15498	VAV1	P00519	ABL1	Y142	D140Y	140	Missense	proximal	-2	no	10.363	10.417	EPSD	TCGA;ICGC;COSMIC	7.039	Up-regulation
TK_Abl_ABL1_Y	P15498	VAV1	P00519	ABL1	Y160	V163M	163	Missense	distal	3	no	7.926	6.919	EPSD	TCGA	7.039	Loss
TK_Abl_ABL1_Y	P15498	VAV1	P00519	ABL1	Y160	E164D	164	Missense	distal	4	no	7.926	7.799	EPSD	TCGA;ICGC	7.039	Down-regulation
TK_Abl_ABL1_Y	P15498	VAV1	P00519	ABL1	Y174	D171N	171	Missense	distal	-3	no	10.850	10.814	PhosphoSitePlus;EPSD	TCGA;ICGC;COSMIC;CCLE	7.039	Down-regulation
TK_Abl_ABL1_Y	P15498	VAV1	P00519	ABL1	Y174	A168V	168	Missense	distal	-6	no	10.850	10.871	PhosphoSitePlus;EPSD	TCGA;ICGC;COSMIC;CCLE	7.039	Up-regulation
TK_Abl_ABL1_Y	P15498	VAV1	P00519	ABL1	Y174	D171E	171	Missense	distal	-3	no	10.850	11.499	PhosphoSitePlus;EPSD	TCGA;ICGC;COSMIC	7.039	Up-regulation
TK_Abl_ABL1_Y	P15498	VAV1	P00519	ABL1	Y267	A263T	263	Missense	distal	-4	no	9.143	8.795	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC;GDSC;CCLE	7.039	Down-regulation
TK_Abl_ABL1_Y	P15498	VAV1	P00519	ABL1	Y727	R728Q	728	Missense	proximal	1	no	6.869	7.135	EPSD	TCGA;ICGC;COSMIC	7.039	Gain
TK_Abl_ABL1_Y	P15498	VAV1	P00519	ABL1	Y826	G823E	823	Missense	distal	-3	no	6.767	7.650	EPSD	TCGA;ICGC;COSMIC	7.039	Gain
TK_Abl_ABL1_Y	P15498	VAV1	P00519	ABL1	Y841	Y844C	844	Missense	distal	3	no	8.589	8.492	EPSD	TCGA;ICGC;COSMIC	7.039	Down-regulation
TK_Abl_ABL1_Y	P15498	VAV1	P00519	ABL1	Y844	Y844C	844	Missense	central	0	yes	7.917	0.000	EPSD	TCGA;ICGC;COSMIC	7.039	Loss
TK_Abl_ABL1_Y	Q9UPY6	WASF3	P00519	ABL1	Y151	F157L	157	Missense	distal	6	no	11.116	10.529	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	7.039	Down-regulation
TK_Abl_ABL1_Y	Q9UPY6	WASF3	P00519	ABL1	Y151	F150L	150	Missense	proximal	-1	no	11.116	11.903	EPSD;PhosphoSitePlus	TCGA;ICGC	7.039	Up-regulation
TK_Abl_ABL1_Y	Q9UPY6	WASF3	P00519	ABL1	Y248	P254S	254	Missense	distal	6	no	11.586	11.614	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	7.039	Up-regulation
TK_Abl_ABL1_Y	Q9UPY6	WASF3	P00519	ABL1	Y248	N255S	255	Missense	distal	7	no	11.586	11.570	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	7.039	Down-regulation
TK_Abl_ABL1_Y	Q9UPY6	WASF3	P00519	ABL1	Y248	T246M	246	Missense	proximal	-2	no	11.586	11.102	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	7.039	Down-regulation
TK_Abl_ABL1_Y	Q9UPY6	WASF3	P00519	ABL1	Y286	E285Q	285	Missense	proximal	-1	no	8.322	6.772	EPSD	TCGA;ICGC;COSMIC	7.039	Loss
TK_Abl_ABL1_Y	Q9UPY6	WASF3	P00519	ABL1	Y286	A282V	282	Missense	distal	-4	no	8.322	8.544	EPSD	TCGA;ICGC;COSMIC	7.039	Up-regulation
TK_Abl_ABL1_Y	Q9UPY6	WASF3	P00519	ABL1	Y286	E283K	283	Missense	distal	-3	no	8.322	7.295	EPSD	TCGA;ICGC;COSMIC	7.039	Down-regulation
TK_Abl_ABL1_Y	Q9UPY6	WASF3	P00519	ABL1	Y286	R287L	287	Missense	proximal	1	no	8.322	7.102	EPSD	TCGA;ICGC;COSMIC	7.039	Down-regulation
TK_Abl_ABL1_Y	Q9UPY6	WASF3	P00519	ABL1	Y337	E336K	336	Missense	proximal	-1	no	10.219	8.525	PhosphoSitePlus;EPSD	TCGA;ICGC;COSMIC	7.039	Down-regulation
TK_Abl_ABL1_Y	Q9UPY6	WASF3	P00519	ABL1	Y337	A332V	332	Missense	distal	-5	no	10.219	10.033	PhosphoSitePlus;EPSD	TCGA;ICGC;COSMIC;CCLE	7.039	Down-regulation
TK_Abl_ABL1_Y	Q9UPY6	WASF3	P00519	ABL1	Y486	D491N	491	Missense	distal	5	no	10.888	10.229	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	7.039	Down-regulation
TK_Abl_ABL1_Y	Q9UPY6	WASF3	P00519	ABL1	Y486	D492N	492	Missense	distal	6	no	10.888	11.493	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	7.039	Up-regulation
TK_Abl_ABL1_Y	Q9UPY6	WASF3	P00519	ABL1	Y486	R481C	481	Missense	distal	-5	no	10.888	8.831	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	7.039	Down-regulation
TK_Abl_ABL1_Y	Q9UPY6	WASF3	P00519	ABL1	Y486	R480W	480	Missense	distal	-6	no	10.888	10.661	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC;GDSC;CCLE	7.039	Down-regulation
TK_Abl_ABL1_Y	P17844	DDX5	P00519	ABL1	Y59	A66G	66	Missense	distal	7	no	7.456	7.462	EPSD	TCGA;ICGC;COSMIC	7.039	Up-regulation
TK_Abl_ABL1_Y	P17844	DDX5	P00519	ABL1	Y59	D64N	64	Missense	distal	5	no	7.456	6.798	EPSD	TCGA;ICGC;COSMIC	7.039	Loss
TK_Abl_ABL1_Y	P17844	DDX5	P00519	ABL1	Y59	P63S	63	Missense	distal	4	no	7.456	7.176	EPSD	TCGA;ICGC;COSMIC	7.039	Down-regulation
TK_Abl_ABL1_Y	P17844	DDX5	P00519	ABL1	Y416	P419R	419	Missense	distal	3	no	9.066	4.424	EPSD	TCGA;ICGC;COSMIC	7.039	Loss
TK_Abl_ABL1_Y	P17844	DDX5	P00519	ABL1	Y535	N532S	532	Missense	distal	-3	no	10.897	10.924	EPSD	TCGA;ICGC;COSMIC	7.039	Up-regulation
TK_Abl_ABL1_Y	P17844	DDX5	P00519	ABL1	Y535	N542S	542	Missense	distal	7	no	10.897	10.881	EPSD	TCGA;ICGC;COSMIC	7.039	Down-regulation
TK_Abl_ABL1_Y	P17844	DDX5	P00519	ABL1	Y535	Q531E	531	Missense	distal	-4	no	10.897	12.383	EPSD	TCGA;ICGC;COSMIC	7.039	Up-regulation
TK_Abl_ABL1_Y	P17844	DDX5	P00519	ABL1	Y535	A528V	528	Missense	distal	-7	no	10.897	11.164	EPSD	TCGA;ICGC;COSMIC	7.039	Up-regulation
TK_Abl_ABL1_Y	P17844	DDX5	P00519	ABL1	Y535	Y540H	540	Missense	distal	5	no	10.897	10.750	EPSD	TCGA;ICGC;COSMIC	7.039	Down-regulation
TK_Abl_ABL1_Y	P17844	DDX5	P00519	ABL1	Y535	N539K	539	Missense	distal	4	no	10.897	10.608	EPSD	TCGA;ICGC	7.039	Down-regulation
TK_Abl_ABL1_Y	P17844	DDX5	P00519	ABL1	Y593	Y593H	593	Missense	central	0	yes	16.480	0.000	PhosphoSitePlus	TCGA;ICGC;COSMIC	7.039	Loss
TK_Abl_ABL1_Y	P17844	DDX5	P00519	ABL1	Y593	P596L	596	Missense	distal	3	no	16.480	13.903	PhosphoSitePlus	TCGA;ICGC;COSMIC	7.039	Down-regulation
TK_Abl_ABL1_Y	P17844	DDX5	P00519	ABL1	Y595	Y593H	593	Missense	proximal	-2	no	8.959	9.298	EPSD	TCGA;ICGC;COSMIC	7.039	Up-regulation
TK_Abl_ABL1_Y	P17844	DDX5	P00519	ABL1	Y595	P596L	596	Missense	proximal	1	no	8.959	8.216	EPSD	TCGA;ICGC;COSMIC	7.039	Down-regulation
TK_Abl_ABL1_Y	P17844	DDX5	P00519	ABL1	Y595	P602H	602	Missense	distal	7	no	8.959	8.936	EPSD	TCGA;ICGC;COSMIC	7.039	Down-regulation
TK_Abl_ABL1_Y	O14818	PSMA7	P00519	ABL1	Y153	S150W	150	Missense	distal	-3	no	11.538	10.816	PhosphoSitePlus;EPSD	TCGA;COSMIC	7.039	Down-regulation
TK_Abl_ABL1_Y	Q9UPN9	TRIM33	P00519	ABL1	Y1018	D1022H	1022	Missense	distal	4	no	11.528	10.759	EPSD	TCGA;ICGC;COSMIC	7.039	Down-regulation
TK_Abl_ABL1_Y	Q9UPN9	TRIM33	P00519	ABL1	Y1018	I1020L	1020	Missense	proximal	2	no	11.528	10.271	EPSD	TCGA;ICGC	7.039	Down-regulation
TK_Abl_ABL1_Y	P46527	CDKN1B	P00519	ABL1	Y88	K81R	81	Missense	distal	-7	no	9.490	9.375	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	7.039	Down-regulation
TK_Abl_ABL1_Y	P46527	CDKN1B	P00519	ABL1	Y89	K96Q	96	Missense	distal	7	no	10.249	10.281	PhosphoSitePlus;EPSD	TCGA;ICGC;COSMIC	7.039	Up-regulation
TK_Abl_ABL1_Y	Q14980	NUMA1	P00519	ABL1	Y827	Q821H	821	Missense	distal	-6	no	7.904	7.794	EPSD	TCGA;ICGC;COSMIC	7.039	Down-regulation
TK_Abl_ABL1_Y	Q14980	NUMA1	P00519	ABL1	Y827	A825V	825	Missense	proximal	-2	no	7.904	8.363	EPSD	TCGA;ICGC	7.039	Up-regulation
TK_Abl_ABL1_Y	Q14980	NUMA1	P00519	ABL1	Y827	A829T	829	Missense	proximal	2	no	7.904	7.710	EPSD	TCGA;ICGC;COSMIC;GDSC;CCLE	7.039	Down-regulation
TK_Abl_ABL1_Y	Q14980	NUMA1	P00519	ABL1	Y827	A829V	829	Missense	proximal	2	no	7.904	6.900	EPSD	TCGA;ICGC;COSMIC	7.039	Loss
TK_Abl_ABL1_Y	P06400	RB1	P00519	ABL1	Y606	D604G	604	Missense	proximal	-2	no	9.160	9.554	EPSD	TCGA;ICGC;COSMIC	7.039	Up-regulation
TK_Abl_ABL1_Y	P06400	RB1	P00519	ABL1	Y805	N803S	803	Missense	proximal	-2	no	10.355	10.469	PhosphoSitePlus	TCGA;ICGC	7.039	Up-regulation
TK_Abl_ABL1_Y	P06400	RB1	P00519	ABL1	Y805	R798W	798	Missense	distal	-7	no	10.355	9.769	PhosphoSitePlus	TCGA;ICGC;COSMIC;GDSC	7.039	Down-regulation
TK_Abl_ABL1_Y	O00429	DNM1L	P00519	ABL1	Y266	L269V	269	Missense	distal	3	no	7.695	8.351	EPSD;PhosphoSitePlus	TCGA;COSMIC	7.039	Up-regulation
TK_Abl_ABL1_Y	O00429	DNM1L	P00519	ABL1	Y266	K271N	271	Missense	distal	5	no	7.695	6.700	EPSD;PhosphoSitePlus	TCGA;CCLE	7.039	Loss
TK_Abl_ABL1_Y	O00429	DNM1L	P00519	ABL1	Y449	C446Y	446	Missense	distal	-3	no	7.069	7.170	EPSD;PhosphoSitePlus	TCGA;COSMIC	7.039	Up-regulation
TK_Abl_ABL1_Y	O00429	DNM1L	P00519	ABL1	Y449	R456G	456	Missense	distal	7	no	7.069	7.041	EPSD;PhosphoSitePlus	TCGA;COSMIC	7.039	Down-regulation
TK_Abl_ABL1_Y	Q16531	DDB1	P00519	ABL1	Y182	I178V	178	Missense	distal	-4	no	10.384	10.289	PhosphoSitePlus;EPSD	TCGA;ICGC;COSMIC	7.039	Down-regulation
TK_Abl_ABL1_Y	Q16531	DDB1	P00519	ABL1	Y182	Y182C	182	Missense	central	0	yes	10.384	0.000	PhosphoSitePlus;EPSD	TCGA;ICGC;COSMIC	7.039	Loss
TK_Abl_ABL1_Y	Q16531	DDB1	P00519	ABL1	Y182	R188Q	188	Missense	distal	6	no	10.384	11.237	PhosphoSitePlus;EPSD	TCGA;ICGC;COSMIC	7.039	Up-regulation
TK_Abl_ABL1_Y	Q16531	DDB1	P00519	ABL1	Y517	L519V	519	Missense	proximal	2	no	7.406	7.687	EPSD	TCGA;ICGC;COSMIC	7.039	Up-regulation
TK_Abl_ABL1_Y	Q16531	DDB1	P00519	ABL1	Y518	L519V	519	Missense	proximal	1	no	6.177	7.987	EPSD	TCGA;ICGC;COSMIC	7.039	Gain
TK_Abl_ABL1_Y	Q16531	DDB1	P00519	ABL1	Y660	R655C	655	Missense	distal	-5	no	7.460	5.403	EPSD	TCGA;ICGC;COSMIC	7.039	Loss
TK_Abl_ABL1_Y	Q16531	DDB1	P00519	ABL1	Y718	R713C	713	Missense	distal	-5	no	7.222	5.166	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	7.039	Loss
TK_Abl_ABL1_Y	Q16531	DDB1	P00519	ABL1	Y718	P716S	716	Missense	proximal	-2	no	7.222	7.614	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	7.039	Up-regulation
TK_Abl_ABL1_Y	Q16531	DDB1	P00519	ABL1	Y718	R713H	713	Missense	distal	-5	no	7.222	5.454	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	7.039	Loss
TK_Abl_ABL1_Y	P35222	CTNNB1	P00519	ABL1	Y86	R90Q	90	Missense	distal	4	no	8.309	7.755	EPSD;PhosphoSitePlus	TCGA;COSMIC	7.039	Down-regulation
TK_Abl_ABL1_Y	P35222	CTNNB1	P00519	ABL1	Y86	R90L	90	Missense	distal	4	no	8.309	7.909	EPSD;PhosphoSitePlus	TCGA	7.039	Down-regulation
TK_Abl_ABL1_Y	P35222	CTNNB1	P00519	ABL1	Y86	G84R	84	Missense	proximal	-2	no	8.309	7.858	EPSD;PhosphoSitePlus	TCGA;COSMIC	7.039	Down-regulation
TK_Abl_ABL1_Y	P35222	CTNNB1	P00519	ABL1	Y86	A80T	80	Missense	distal	-6	no	8.309	8.297	EPSD;PhosphoSitePlus	TCGA	7.039	Down-regulation
TK_Abl_ABL1_Y	P35222	CTNNB1	P00519	ABL1	Y333	E334A	334	Missense	proximal	1	no	6.591	7.697	EPSD	TCGA;COSMIC	7.039	Gain
TK_Abl_ABL1_Y	P35222	CTNNB1	P00519	ABL1	Y333	K335T	335	Missense	proximal	2	no	6.591	7.100	EPSD	TCGA;COSMIC	7.039	Gain
TK_Abl_ABL1_Y	P35222	CTNNB1	P00519	ABL1	Y333	K335I	335	Missense	proximal	2	no	6.591	7.266	EPSD	TCGA;COSMIC	7.039	Gain
TK_Abl_ABL1_Y	P35222	CTNNB1	P00519	ABL1	Y333	L336P	336	Missense	distal	3	no	6.591	9.169	EPSD	TCGA;COSMIC	7.039	Gain
TK_Abl_ABL1_Y	P35222	CTNNB1	P00519	ABL1	Y716	R717H	717	Missense	proximal	1	no	7.966	6.846	EPSD	TCGA;COSMIC	7.039	Loss
TK_Abl_ABL1_Y	P35222	CTNNB1	P00519	ABL1	Y716	P714R	714	Missense	proximal	-2	no	7.966	7.591	EPSD	TCGA;COSMIC	7.039	Down-regulation
TK_Abl_ABL1_Y	P35222	CTNNB1	P00519	ABL1	Y716	P714L	714	Missense	proximal	-2	no	7.966	7.381	EPSD	TCGA;COSMIC	7.039	Down-regulation
TK_Abl_ABL1_Y	P43403	ZAP70	P00519	ABL1	Y221	K217M	217	Missense	distal	-4	no	10.683	11.248	EPSD	TCGA;ICGC;COSMIC	7.039	Up-regulation
TK_Abl_ABL1_Y	P43403	ZAP70	P00519	ABL1	Y221	T227I	227	Missense	distal	6	no	10.683	10.660	EPSD	TCGA;ICGC;COSMIC	7.039	Down-regulation
TK_Abl_ABL1_Y	P43403	ZAP70	P00519	ABL1	Y319	E324K	324	Missense	distal	5	no	13.297	13.991	PhosphoSitePlus	TCGA;ICGC;COSMIC	7.039	Up-regulation
TK_Abl_ABL1_Y	P43403	ZAP70	P00519	ABL1	Y319	V314M	314	Missense	distal	-5	no	13.297	12.457	PhosphoSitePlus	TCGA;ICGC;COSMIC	7.039	Down-regulation
TK_Abl_ABL1_Y	P43403	ZAP70	P00519	ABL1	Y319	D321N	321	Missense	proximal	2	no	13.297	13.640	PhosphoSitePlus	TCGA;ICGC;COSMIC	7.039	Up-regulation
TK_Abl_ABL1_Y	P43403	ZAP70	P00519	ABL1	Y493	R496H	496	Missense	distal	3	no	6.532	7.957	EPSD	TCGA;ICGC;COSMIC	7.039	Gain
TK_Abl_ABL1_Y	P43403	ZAP70	P00519	ABL1	Y597	Q591P	591	Missense	distal	-6	no	9.155	9.128	EPSD	TCGA;ICGC;COSMIC	7.039	Down-regulation
TK_Abl_ABL1_Y	P43403	ZAP70	P00519	ABL1	Y597	A601V	601	Missense	distal	4	no	9.155	8.714	EPSD	TCGA;ICGC;COSMIC	7.039	Down-regulation
TK_Abl_ABL1_Y	P43403	ZAP70	P00519	ABL1	Y598	E605Q	605	Missense	distal	7	no	7.684	7.748	EPSD	TCGA;ICGC;COSMIC	7.039	Up-regulation
TK_Abl_ABL1_Y	P43403	ZAP70	P00519	ABL1	Y598	Q591P	591	Missense	distal	-7	no	7.684	7.292	EPSD	TCGA;ICGC;COSMIC	7.039	Down-regulation
TK_Abl_ABL1_Y	P43403	ZAP70	P00519	ABL1	Y598	A601V	601	Missense	distal	3	no	7.684	9.865	EPSD	TCGA;ICGC;COSMIC	7.039	Up-regulation
TK_Abl_ABL1_Y	Q8IZP0	ABI1	P00519	ABL1	Y455	A453T	453	Missense	proximal	-2	no	8.579	8.795	EPSD	TCGA;COSMIC	7.039	Up-regulation
TK_Abl_ABL1_Y	P15391	CD19	P00519	ABL1	Y378	V385I	385	Missense	distal	7	no	7.896	7.840	EPSD	TCGA;ICGC;COSMIC	7.039	Down-regulation
TK_Abl_ABL1_Y	P15391	CD19	P00519	ABL1	Y378	P376R	376	Missense	proximal	-2	no	7.896	7.520	EPSD	TCGA;ICGC;COSMIC	7.039	Down-regulation
TK_Abl_ABL1_Y	P15391	CD19	P00519	ABL1	Y409	G408D	408	Missense	proximal	-1	no	8.242	10.291	EPSD	TCGA;ICGC;COSMIC	7.039	Up-regulation
TK_Abl_ABL1_Y	P15391	CD19	P00519	ABL1	Y508	A510V	510	Missense	proximal	2	no	9.625	8.622	PhosphoSitePlus	TCGA;COSMIC;CCLE	7.039	Down-regulation
TK_Abl_ABL1_Y	P15391	CD19	P00519	ABL1	Y531	E526K	526	Missense	distal	-5	no	7.945	8.153	EPSD	TCGA;COSMIC	7.039	Up-regulation
TK_Abl_ABL1_Y	Q99638	RAD9A	P00519	ABL1	Y28	P31T	31	Missense	distal	3	no	7.846	4.301	PhosphoSitePlus	TCGA;ICGC;COSMIC	7.039	Loss
TK_Abl_ABL1_Y	Q99638	RAD9A	P00519	ABL1	Y28	G24W	24	Missense	distal	-4	no	7.846	5.322	PhosphoSitePlus	TCGA;ICGC;COSMIC	7.039	Loss
TK_Abl_ABL1_Y	Q99638	RAD9A	P00519	ABL1	Y28	G24V	24	Missense	distal	-4	no	7.846	7.542	PhosphoSitePlus	TCGA;ICGC;COSMIC	7.039	Down-regulation
TK_Abl_ABL1_Y	O15269	SPTLC1	P00519	ABL1	Y18	V11L	11	Missense	distal	-7	no	7.111	6.624	EPSD	TCGA;ICGC	7.039	Loss
TK_Abl_ABL1_Y	O15269	SPTLC1	P00519	ABL1	Y164	K157N	157	Missense	distal	-7	no	8.622	9.206	PhosphoSitePlus	TCGA;ICGC;COSMIC	7.039	Up-regulation
TK_Abl_ABL1_Y	O15269	SPTLC1	P00519	ABL1	Y164	A169T	169	Missense	distal	5	no	8.622	8.230	PhosphoSitePlus	TCGA;ICGC	7.039	Down-regulation
TK_Abl_ABL1_Y	Q9Y6H1	CHCHD2	P00519	ABL1	Y99	T98I	98	Missense	proximal	-1	no	11.718	13.635	PhosphoSitePlus	TCGA;ICGC;COSMIC	7.039	Up-regulation
TK_Abl_ABL1_Y	Q9Y6H1	CHCHD2	P00519	ABL1	Y99	G104E	104	Missense	distal	5	no	11.718	11.009	PhosphoSitePlus	TCGA;ICGC;COSMIC	7.039	Down-regulation
TK_Abl_ABL1_Y	Q9Y6H1	CHCHD2	P00519	ABL1	Y99	A93V	93	Missense	distal	-6	no	11.718	11.739	PhosphoSitePlus	TCGA;ICGC;COSMIC	7.039	Up-regulation
TK_Abl_ABL1_Y	Q9Y6H1	CHCHD2	P00519	ABL1	Y99	Q103H	103	Missense	distal	4	no	11.718	11.473	PhosphoSitePlus	TCGA;ICGC;COSMIC	7.039	Down-regulation
TK_Abl_ABL1_Y	Q13043	STK4	P00519	ABL1	Y45	V44A	44	Missense	proximal	-1	no	9.345	9.796	EPSD	TCGA;ICGC;COSMIC	7.039	Up-regulation
TK_Abl_ABL1_Y	Q92769	HDAC2	P00519	ABL1	Y359	K362N	362	Missense	distal	3	no	9.001	9.342	EPSD	TCGA;COSMIC	7.039	Up-regulation
TK_Abl_ABL1_Y	Q92769	HDAC2	P00519	ABL1	Y359	Q354K	354	Missense	distal	-5	no	9.001	8.899	EPSD	TCGA;COSMIC	7.039	Down-regulation
TK_Abl_ABL1_Y	Q92769	HDAC2	P00519	ABL1	Y359	R366C	366	Missense	distal	7	no	9.001	8.918	EPSD	TCGA	7.039	Down-regulation
TK_Abl_ABL1_Y	Q9H2X6	HIPK2	P00519	ABL1	Y367	E371Q	371	Missense	distal	4	no	8.524	7.873	PhosphoSitePlus	TCGA;ICGC;COSMIC	7.039	Down-regulation
TK_Abl_ABL1_Y	Q9H2X6	HIPK2	P00519	ABL1	Y367	P370S	370	Missense	distal	3	no	8.524	5.389	PhosphoSitePlus	TCGA;ICGC;COSMIC	7.039	Loss
TK_Abl_ABL1_Y	Q9H2X6	HIPK2	P00519	ABL1	Y443	P444S	444	Missense	proximal	1	no	9.217	9.985	EPSD	TCGA;ICGC;COSMIC	7.039	Up-regulation
TK_Abl_ABL1_Y	Q9H2X6	HIPK2	P00519	ABL1	Y443	D438G	438	Missense	distal	-5	no	9.217	9.187	EPSD	TCGA;ICGC;COSMIC	7.039	Down-regulation
TK_Abl_ABL1_Y	Q9H2X6	HIPK2	P00519	ABL1	Y443	R437C	437	Missense	distal	-6	no	9.217	9.006	EPSD	TCGA;ICGC;COSMIC	7.039	Down-regulation
TK_Abl_ABL1_Y	Q9H2X6	HIPK2	P00519	ABL1	Y1197	Q1194K	1194	Missense	distal	-3	no	8.206	7.902	EPSD	TCGA;ICGC;COSMIC	7.039	Down-regulation
TK_Abl_ABL1_Y	Q14847	LASP1	P00519	ABL1	Y44	K42N	42	Missense	proximal	-2	no	6.347	7.154	EPSD	TCGA;COSMIC	7.039	Gain
TK_Abl_ABL1_Y	Q14847	LASP1	P00519	ABL1	Y171	V170I	170	Missense	proximal	-1	no	10.568	12.334	PhosphoSitePlus	TCGA;COSMIC	7.039	Up-regulation
TK_Abl_ABL1_Y	Q14847	LASP1	P00519	ABL1	Y171	P165S	165	Missense	distal	-6	no	10.568	10.587	PhosphoSitePlus	TCGA;COSMIC	7.039	Up-regulation
TK_Abl_ABL1_Y	Q14847	LASP1	P00519	ABL1	Y257	G251R	251	Missense	distal	-6	no	7.001	7.219	EPSD	TCGA	7.039	Gain
TK_Abl_ABL1_Y	Q14847	LASP1	P00519	ABL1	Y257	L253P	253	Missense	distal	-4	no	7.001	8.192	EPSD	TCGA;ICGC;COSMIC	7.039	Gain
TK_Abl_ABL1_Y	Q15139	PRKD1	P00519	ABL1	Y463	E470G	470	Missense	distal	7	no	11.364	11.373	PhosphoSitePlus	TCGA;COSMIC	7.039	Up-regulation
TK_Abl_ABL1_Y	O95433	AHSA1	P00519	ABL1	Y151	R145G	145	Missense	distal	-6	no	7.313	7.095	EPSD	TCGA;ICGC;COSMIC	7.039	Down-regulation
TK_Abl_ABL1_Y	O95433	AHSA1	P00519	ABL1	Y151	M148V	148	Missense	distal	-3	no	7.313	7.626	EPSD	TCGA;ICGC;COSMIC	7.039	Up-regulation
TK_Abl_ABL1_Y	O95433	AHSA1	P00519	ABL1	Y223	T228A	228	Missense	distal	5	no	9.095	9.486	PhosphoSitePlus	TCGA;ICGC;COSMIC	7.039	Up-regulation
TK_Abl_ABL1_Y	P25490	YY1	P00519	ABL1	Y383	H377R	377	Missense	distal	-6	no	8.028	8.200	EPSD	TCGA	7.039	Up-regulation
TK_Abl_ABL1_Y	P25490	YY1	P00519	ABL1	Y383	G379R	379	Missense	distal	-4	no	8.028	7.831	EPSD	TCGA;ICGC;COSMIC;GDSC;CCLE	7.039	Down-regulation
TK_Abl_ABL1_Y	P42768	WAS	P00519	ABL1	Y102	Q104H	104	Missense	proximal	2	no	7.430	7.143	EPSD	TCGA;ICGC;COSMIC	7.039	Down-regulation
TK_Abl_ABL1_Y	P42768	WAS	P00519	ABL1	Y102	E98V	98	Missense	distal	-4	no	7.430	6.079	EPSD	TCGA;ICGC;COSMIC	7.039	Loss
TK_Abl_ABL1_Y	P42768	WAS	P00519	ABL1	Y102	L105I	105	Missense	distal	3	no	7.430	6.569	EPSD	TCGA;ICGC	7.039	Loss
TK_Abl_ABL1_Y	P42768	WAS	P00519	ABL1	Y291	D292N	292	Missense	proximal	1	no	9.254	8.953	PhosphoSitePlus	TCGA;ICGC;COSMIC	7.039	Down-regulation
TK_Abl_ABL1_Y	P42768	WAS	P00519	ABL1	Y291	F293L	293	Missense	proximal	2	no	9.254	8.667	PhosphoSitePlus	TCGA;ICGC;COSMIC	7.039	Down-regulation
TK_Abl_ABL1_Y	P11387	TOP1	P00519	ABL1	Y125	P128T	128	Missense	distal	3	no	8.928	5.382	EPSD	TCGA;ICGC;COSMIC	7.039	Loss
TK_Abl_ABL1_Y	P11387	TOP1	P00519	ABL1	Y125	P128L	128	Missense	distal	3	no	8.928	6.350	EPSD	TCGA;ICGC;COSMIC	7.039	Loss
TK_Abl_ABL1_Y	P11387	TOP1	P00519	ABL1	Y231	P225L	225	Missense	distal	-6	no	7.441	7.288	EPSD	TCGA;ICGC;COSMIC	7.039	Down-regulation
TK_Abl_ABL1_Y	P11387	TOP1	P00519	ABL1	Y231	E236D	236	Missense	distal	5	no	7.441	7.799	EPSD	TCGA;ICGC;COSMIC	7.039	Up-regulation
TK_Abl_ABL1_Y	P11387	TOP1	P00519	ABL1	Y426	Y426C	426	Missense	central	0	yes	7.303	0.000	EPSD	TCGA;ICGC;COSMIC;GDSC;CCLE	7.039	Loss
TK_Abl_ABL1_Y	P56962	STX17	P00519	ABL1	Y157	Q151E	151	Missense	distal	-6	no	15.579	15.634	PhosphoSitePlus	TCGA;ICGC;COSMIC	7.039	Up-regulation
TK_Abl_ABL1_Y	P56962	STX17	P00519	ABL1	Y157	A158V	158	Missense	proximal	1	no	15.579	14.562	PhosphoSitePlus	TCGA;ICGC	7.039	Down-regulation
Other_CDC7_CDC7_ST	P19338	NCL	O00311	CDC7	S41	D40N	40	Missense	proximal	-1	no	72.467	71.008	EPSD	TCGA	65.097	Down-regulation
Other_CDC7_CDC7_ST	P19338	NCL	O00311	CDC7	S41	V47I	47	Missense	distal	6	no	72.467	72.794	EPSD	TCGA;ICGC;COSMIC	65.097	Up-regulation
Other_CDC7_CDC7_ST	P19338	NCL	O00311	CDC7	T76	K71N	71	Missense	distal	-5	no	81.375	84.871	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC;GDSC;CCLE	65.097	Up-regulation
Other_CDC7_CDC7_ST	P19338	NCL	O00311	CDC7	T76	P77L	77	Missense	proximal	1	no	81.375	59.797	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	65.097	Loss
Other_CDC7_CDC7_ST	P19338	NCL	O00311	CDC7	T92	A91T	91	Missense	proximal	-1	no	65.862	66.613	EPSD	TCGA;ICGC;COSMIC	65.097	Up-regulation
Other_CDC7_CDC7_ST	P19338	NCL	O00311	CDC7	T121	G123A	123	Missense	proximal	2	no	72.728	73.854	PhosphoSitePlus;EPSD	TCGA;ICGC;COSMIC	65.097	Up-regulation
Other_CDC7_CDC7_ST	P19338	NCL	O00311	CDC7	S206	T213S	213	Missense	distal	7	no	77.704	79.130	EPSD	TCGA;ICGC;COSMIC	65.097	Up-regulation
Other_CDC7_CDC7_ST	P19338	NCL	O00311	CDC7	S206	D199N	199	Missense	distal	-7	no	77.704	78.151	EPSD	TCGA;ICGC;COSMIC	65.097	Up-regulation
Other_CDC7_CDC7_ST	P19338	NCL	O00311	CDC7	S458	Y463C	463	Missense	distal	5	no	70.617	69.654	EPSD	TCGA;ICGC;COSMIC	65.097	Down-regulation
Other_CDC7_CDC7_ST	P19338	NCL	O00311	CDC7	S458	G456V	456	Missense	proximal	-2	no	70.617	71.306	EPSD	TCGA;ICGC;COSMIC	65.097	Up-regulation
Other_CDC7_CDC7_ST	P19338	NCL	O00311	CDC7	S458	G456W	456	Missense	proximal	-2	no	70.617	71.231	EPSD	TCGA;ICGC;COSMIC	65.097	Up-regulation
Other_CDC7_CDC7_ST	P19338	NCL	O00311	CDC7	S458	D455V	455	Missense	distal	-3	no	70.617	70.766	EPSD	TCGA;ICGC;COSMIC	65.097	Up-regulation
Other_CDC7_CDC7_ST	P19338	NCL	O00311	CDC7	S458	D455N	455	Missense	distal	-3	no	70.617	70.584	EPSD	TCGA;ICGC;COSMIC	65.097	Down-regulation
Other_CDC7_CDC7_ST	P19338	NCL	O00311	CDC7	S458	R457Q	457	Missense	proximal	-1	no	70.617	70.901	EPSD	TCGA;ICGC	65.097	Up-regulation
Other_CDC7_CDC7_ST	P19338	NCL	O00311	CDC7	S532	A531V	531	Missense	proximal	-1	no	75.509	73.812	EPSD	TCGA;ICGC;COSMIC	65.097	Down-regulation
Other_CDC7_CDC7_ST	P19338	NCL	O00311	CDC7	S532	E534K	534	Missense	proximal	2	no	75.509	73.390	EPSD	TCGA;ICGC;COSMIC	65.097	Down-regulation
Other_CDC7_CDC7_ST	P19338	NCL	O00311	CDC7	S532	E538D	538	Missense	distal	6	no	75.509	75.553	EPSD	TCGA;ICGC	65.097	Up-regulation
Other_CDC7_CDC7_ST	P19338	NCL	O00311	CDC7	S532	A531P	531	Missense	proximal	-1	no	75.509	73.526	EPSD	TCGA;ICGC	65.097	Down-regulation
Other_CDC7_CDC7_ST	P19338	NCL	O00311	CDC7	S591	E585K	585	Missense	distal	-6	no	77.786	76.693	EPSD	TCGA;ICGC;COSMIC	65.097	Down-regulation
Other_CDC7_CDC7_ST	P19338	NCL	O00311	CDC7	S591	R597W	597	Missense	distal	6	no	77.786	77.563	EPSD	TCGA;ICGC;COSMIC	65.097	Down-regulation
Other_CDC7_CDC7_ST	P19338	NCL	O00311	CDC7	S591	D593G	593	Missense	proximal	2	no	77.786	79.045	EPSD	TCGA;ICGC;COSMIC	65.097	Up-regulation
Other_CDC7_CDC7_ST	P55081	MFAP1	O00311	CDC7	S116	V120I	120	Missense	distal	4	no	83.039	82.942	PhosphoSitePlus	TCGA	65.097	Down-regulation
Other_CDC7_CDC7_ST	P55081	MFAP1	O00311	CDC7	S116	E111K	111	Missense	distal	-5	no	83.039	84.028	PhosphoSitePlus	TCGA;ICGC;COSMIC	65.097	Up-regulation
Other_CDC7_CDC7_ST	P55081	MFAP1	O00311	CDC7	S132	E134K	134	Missense	proximal	2	no	66.210	64.091	EPSD	TCGA;ICGC;COSMIC	65.097	Loss
Other_CDC7_CDC7_ST	P55081	MFAP1	O00311	CDC7	S132	E138D	138	Missense	distal	6	no	66.210	66.254	EPSD	TCGA;ICGC	65.097	Up-regulation
Other_CDC7_CDC7_ST	P55081	MFAP1	O00311	CDC7	S132	E137D	137	Missense	distal	5	no	66.210	66.703	EPSD	TCGA;ICGC;COSMIC	65.097	Up-regulation
Other_CDC7_CDC7_ST	P55081	MFAP1	O00311	CDC7	S132	R126S	126	Missense	distal	-6	no	66.210	65.182	EPSD	TCGA;ICGC;COSMIC	65.097	Down-regulation
Other_CDC7_CDC7_ST	P55081	MFAP1	O00311	CDC7	S133	E134K	134	Missense	proximal	1	no	82.583	60.774	EPSD	TCGA;ICGC;COSMIC	65.097	Loss
Other_CDC7_CDC7_ST	P55081	MFAP1	O00311	CDC7	S133	E138D	138	Missense	distal	5	no	82.583	83.076	EPSD	TCGA;ICGC	65.097	Up-regulation
Other_CDC7_CDC7_ST	P55081	MFAP1	O00311	CDC7	S133	E137D	137	Missense	distal	4	no	82.583	82.256	EPSD	TCGA;ICGC;COSMIC	65.097	Down-regulation
Other_CDC7_CDC7_ST	P55081	MFAP1	O00311	CDC7	S133	R126S	126	Missense	distal	-7	no	82.583	79.429	EPSD	TCGA;ICGC;COSMIC	65.097	Down-regulation
Other_CDC7_CDC7_ST	P55081	MFAP1	O00311	CDC7	S179	E184K	184	Missense	distal	5	no	71.787	72.160	EPSD	TCGA;ICGC;COSMIC	65.097	Up-regulation
Other_CDC7_CDC7_ST	P55081	MFAP1	O00311	CDC7	S179	E180K	180	Missense	proximal	1	no	71.787	49.977	EPSD	TCGA;ICGC;COSMIC	65.097	Loss
Other_CDC7_CDC7_ST	P55081	MFAP1	O00311	CDC7	S401	D398A	398	Missense	distal	-3	no	73.140	73.217	EPSD	TCGA;ICGC;COSMIC	65.097	Up-regulation
Other_CDC7_CDC7_ST	P55081	MFAP1	O00311	CDC7	S401	Q397E	397	Missense	distal	-4	no	73.140	72.863	EPSD	TCGA;ICGC;COSMIC	65.097	Down-regulation
Other_CDC7_CDC7_ST	P49736	MCM2	O00311	CDC7	S4	E3K	3	Missense	proximal	-1	no	75.939	73.068	EPSD;PhosphoSitePlus	TCGA;ICGC	65.097	Down-regulation
Other_CDC7_CDC7_ST	P49736	MCM2	O00311	CDC7	S5	E3K	3	Missense	proximal	-2	no	83.157	83.893	PhosphoSitePlus;EPSD	TCGA;ICGC	65.097	Up-regulation
Other_CDC7_CDC7_ST	P49736	MCM2	O00311	CDC7	S5	T9I	9	Missense	distal	4	no	83.157	81.456	PhosphoSitePlus;EPSD	TCGA;ICGC;COSMIC	65.097	Down-regulation
Other_CDC7_CDC7_ST	P49736	MCM2	O00311	CDC7	S7	E3K	3	Missense	distal	-4	no	78.162	77.875	EPSD;PhosphoSitePlus	TCGA;ICGC	65.097	Down-regulation
Other_CDC7_CDC7_ST	P49736	MCM2	O00311	CDC7	S7	T9I	9	Missense	proximal	2	no	78.162	78.545	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	65.097	Up-regulation
Other_CDC7_CDC7_ST	P49736	MCM2	O00311	CDC7	S26	D22G	22	Missense	distal	-4	no	74.298	75.962	EPSD	TCGA;ICGC	65.097	Up-regulation
Other_CDC7_CDC7_ST	P49736	MCM2	O00311	CDC7	S27	D22G	22	Missense	distal	-5	no	82.312	73.935	EPSD;PhosphoSitePlus	TCGA;ICGC	65.097	Down-regulation
Other_CDC7_CDC7_ST	P49736	MCM2	O00311	CDC7	S31	D36N	36	Missense	distal	5	no	76.100	76.322	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	65.097	Up-regulation
Other_CDC7_CDC7_ST	P49736	MCM2	O00311	CDC7	S31	L38I	38	Missense	distal	7	no	76.100	73.982	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	65.097	Down-regulation
Other_CDC7_CDC7_ST	P49736	MCM2	O00311	CDC7	S40	D36N	36	Missense	distal	-4	no	80.370	81.473	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	65.097	Up-regulation
Other_CDC7_CDC7_ST	P49736	MCM2	O00311	CDC7	S40	L38I	38	Missense	proximal	-2	no	80.370	79.870	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	65.097	Down-regulation
Other_CDC7_CDC7_ST	P49736	MCM2	O00311	CDC7	S41	D36N	36	Missense	distal	-5	no	87.051	88.513	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	65.097	Up-regulation
Other_CDC7_CDC7_ST	P49736	MCM2	O00311	CDC7	S41	L38I	38	Missense	distal	-3	no	87.051	87.079	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	65.097	Up-regulation
Other_CDC7_CDC7_ST	P49736	MCM2	O00311	CDC7	S53	D51H	51	Missense	proximal	-2	no	80.927	81.860	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	65.097	Up-regulation
Other_CDC7_CDC7_ST	P49736	MCM2	O00311	CDC7	S53	E50D	50	Missense	distal	-3	no	80.927	81.031	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	65.097	Up-regulation
Other_CDC7_CDC7_ST	P49736	MCM2	O00311	CDC7	S108	E111G	111	Missense	distal	3	no	77.445	77.071	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	65.097	Down-regulation
Other_CDC7_CDC7_ST	P49736	MCM2	O00311	CDC7	S139	R146H	146	Missense	distal	7	no	81.331	81.827	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	65.097	Up-regulation
Other_CDC7_CDC7_ST	P49736	MCM2	O00311	CDC7	S139	E145K	145	Missense	distal	6	no	81.331	81.332	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	65.097	Up-regulation
Other_CDC7_CDC7_ST	P49736	MCM2	O00311	CDC7	S139	R132H	132	Missense	distal	-7	no	81.331	83.505	EPSD;PhosphoSitePlus	TCGA;ICGC;CCLE	65.097	Up-regulation
Other_CDC7_CDC7_ST	P49736	MCM2	O00311	CDC7	S220	R218H	218	Missense	proximal	-2	no	79.669	80.441	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC;GDSC	65.097	Up-regulation
Other_CDC7_CDC7_ST	P49736	MCM2	O00311	CDC7	S220	E225D	225	Missense	distal	5	no	79.669	80.162	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	65.097	Up-regulation
Other_CDC7_CDC7_ST	P49736	MCM2	O00311	CDC7	S220	N213D	213	Missense	distal	-7	no	79.669	79.222	EPSD;PhosphoSitePlus	TCGA;ICGC	65.097	Down-regulation
Other_CDC7_CDC7_ST	P49736	MCM2	O00311	CDC7	S381	P382S	382	Missense	proximal	1	no	73.894	69.583	EPSD	TCGA;ICGC	65.097	Down-regulation
Other_CDC7_CDC7_ST	P49736	MCM2	O00311	CDC7	S759	R765W	765	Missense	distal	6	no	70.139	69.915	EPSD	TCGA;ICGC;COSMIC	65.097	Down-regulation
Other_CDC7_CDC7_ST	O00311	CDC7	O00311	CDC7	S16	F22S	22	Missense	distal	6	no	70.888	71.032	EPSD	TCGA;ICGC	65.097	Up-regulation
Other_CDC7_CDC7_ST	O00311	CDC7	O00311	CDC7	S216	K212Q	212	Missense	distal	-4	no	83.881	84.445	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	65.097	Up-regulation
Other_CDC7_CDC7_ST	O00311	CDC7	O00311	CDC7	S239	V242I	242	Missense	distal	3	no	73.820	73.906	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	65.097	Up-regulation
Other_CDC7_CDC7_ST	O00311	CDC7	O00311	CDC7	S277	Q283K	283	Missense	distal	6	no	89.579	89.675	EPSD;PhosphoSitePlus	TCGA	65.097	Up-regulation
Other_CDC7_CDC7_ST	O00311	CDC7	O00311	CDC7	S277	D272Y	272	Missense	distal	-5	no	89.579	79.099	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	65.097	Down-regulation
Other_CDC7_CDC7_ST	O00311	CDC7	O00311	CDC7	S285	Q283K	283	Missense	proximal	-2	no	76.028	76.893	EPSD;PhosphoSitePlus	TCGA	65.097	Up-regulation
Other_CDC7_CDC7_ST	O00311	CDC7	O00311	CDC7	S285	R290I	290	Missense	distal	5	no	76.028	76.110	EPSD;PhosphoSitePlus	TCGA;COSMIC	65.097	Up-regulation
Other_CDC7_CDC7_ST	O00311	CDC7	O00311	CDC7	S296	R290I	290	Missense	distal	-6	no	79.325	79.407	EPSD;PhosphoSitePlus	TCGA;COSMIC	65.097	Up-regulation
Other_CDC7_CDC7_ST	O00311	CDC7	O00311	CDC7	S296	E301D	301	Missense	distal	5	no	79.325	79.818	EPSD;PhosphoSitePlus	TCGA;COSMIC	65.097	Up-regulation
Other_CDC7_CDC7_ST	O00311	CDC7	O00311	CDC7	S296	H295Y	295	Missense	proximal	-1	no	79.325	76.254	EPSD;PhosphoSitePlus	TCGA;COSMIC	65.097	Down-regulation
Other_CDC7_CDC7_ST	O00311	CDC7	O00311	CDC7	S296	S297F	297	Missense	proximal	1	no	79.325	77.522	EPSD;PhosphoSitePlus	TCGA;COSMIC	65.097	Down-regulation
Other_CDC7_CDC7_ST	O00311	CDC7	O00311	CDC7	S297	R290I	290	Missense	distal	-7	no	77.322	76.420	EPSD;PhosphoSitePlus	TCGA;COSMIC	65.097	Down-regulation
Other_CDC7_CDC7_ST	O00311	CDC7	O00311	CDC7	S297	E301D	301	Missense	distal	4	no	77.322	76.995	EPSD;PhosphoSitePlus	TCGA;COSMIC	65.097	Down-regulation
Other_CDC7_CDC7_ST	O00311	CDC7	O00311	CDC7	S297	H295Y	295	Missense	proximal	-2	no	77.322	78.542	EPSD;PhosphoSitePlus	TCGA;COSMIC	65.097	Up-regulation
Other_CDC7_CDC7_ST	O00311	CDC7	O00311	CDC7	S297	S297F	297	Missense	central	0	yes	77.322	0.000	EPSD;PhosphoSitePlus	TCGA;COSMIC	65.097	Loss
Other_CDC7_CDC7_ST	O00311	CDC7	O00311	CDC7	S302	H295Y	295	Missense	distal	-7	no	62.787	68.021	EPSD	TCGA;COSMIC	65.097	Gain
Other_CDC7_CDC7_ST	O00311	CDC7	O00311	CDC7	S318	R319K	319	Missense	proximal	1	no	73.169	65.814	PhosphoSitePlus;EPSD	TCGA;COSMIC	65.097	Down-regulation
Other_CDC7_CDC7_ST	O00311	CDC7	O00311	CDC7	T356	T350A	350	Missense	distal	-6	no	65.358	63.648	EPSD	TCGA;COSMIC	65.097	Loss
Other_CDC7_CDC7_ST	O00311	CDC7	O00311	CDC7	S490	K492N	492	Missense	proximal	2	no	66.904	65.563	EPSD	TCGA;ICGC;COSMIC	65.097	Down-regulation
Other_CDC7_CDC7_ST	Q9HAW4	CLSPN	O00311	CDC7	S67	S67F	67	Missense	central	0	yes	86.013	0.000	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	65.097	Loss
Other_CDC7_CDC7_ST	Q9HAW4	CLSPN	O00311	CDC7	S67	Q63E	63	Missense	distal	-4	no	86.013	85.735	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	65.097	Down-regulation
Other_CDC7_CDC7_ST	Q9HAW4	CLSPN	O00311	CDC7	S83	E85K	85	Missense	proximal	2	no	66.323	64.204	EPSD	TCGA;ICGC;COSMIC;GDSC	65.097	Loss
Other_CDC7_CDC7_ST	Q9HAW4	CLSPN	O00311	CDC7	S83	N88Y	88	Missense	distal	5	no	66.323	67.525	EPSD	TCGA;ICGC;COSMIC	65.097	Up-regulation
Other_CDC7_CDC7_ST	Q9HAW4	CLSPN	O00311	CDC7	S83	P76S	76	Missense	distal	-7	no	66.323	62.877	EPSD	TCGA;ICGC;COSMIC	65.097	Loss
Other_CDC7_CDC7_ST	Q9HAW4	CLSPN	O00311	CDC7	S83	E90D	90	Missense	distal	7	no	66.323	67.928	EPSD	TCGA;ICGC;COSMIC	65.097	Up-regulation
Other_CDC7_CDC7_ST	Q9HAW4	CLSPN	O00311	CDC7	S225	G218V	218	Missense	distal	-7	no	65.439	67.433	EPSD	TCGA;ICGC;COSMIC	65.097	Up-regulation
Other_CDC7_CDC7_ST	Q9HAW4	CLSPN	O00311	CDC7	S235	I236T	236	Missense	proximal	1	no	66.357	57.171	EPSD	TCGA;ICGC;COSMIC	65.097	Loss
Other_CDC7_CDC7_ST	Q9HAW4	CLSPN	O00311	CDC7	S235	A238T	238	Missense	distal	3	no	66.357	66.218	EPSD	TCGA;ICGC;COSMIC	65.097	Down-regulation
Other_CDC7_CDC7_ST	Q9HAW4	CLSPN	O00311	CDC7	S260	S253F	253	Missense	distal	-7	no	77.144	78.974	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	65.097	Up-regulation
Other_CDC7_CDC7_ST	Q9HAW4	CLSPN	O00311	CDC7	S260	G257V	257	Missense	distal	-3	no	77.144	77.141	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	65.097	Down-regulation
Other_CDC7_CDC7_ST	Q9HAW4	CLSPN	O00311	CDC7	S341	S336P	336	Missense	distal	-5	no	66.744	68.146	EPSD	TCGA;ICGC;COSMIC	65.097	Up-regulation
Other_CDC7_CDC7_ST	Q9HAW4	CLSPN	O00311	CDC7	S358	A351V	351	Missense	distal	-7	no	60.827	67.251	EPSD	TCGA;ICGC;COSMIC	65.097	Gain
Other_CDC7_CDC7_ST	Q9HAW4	CLSPN	O00311	CDC7	S480	E487K	487	Missense	distal	7	no	69.389	70.811	EPSD	TCGA;ICGC;COSMIC	65.097	Up-regulation
Other_CDC7_CDC7_ST	Q9HAW4	CLSPN	O00311	CDC7	S480	E475K	475	Missense	distal	-5	no	69.389	70.377	EPSD	TCGA;ICGC;COSMIC	65.097	Up-regulation
Other_CDC7_CDC7_ST	Q9HAW4	CLSPN	O00311	CDC7	S480	G484V	484	Missense	distal	4	no	69.389	68.867	EPSD	TCGA;ICGC;COSMIC	65.097	Down-regulation
Other_CDC7_CDC7_ST	Q9HAW4	CLSPN	O00311	CDC7	S704	G707V	707	Missense	distal	3	no	79.769	79.669	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	65.097	Down-regulation
Other_CDC7_CDC7_ST	Q9HAW4	CLSPN	O00311	CDC7	S721	S723Y	723	Missense	proximal	2	no	79.382	71.636	EPSD;PhosphoSitePlus	TCGA;COSMIC	65.097	Down-regulation
Other_CDC7_CDC7_ST	Q9HAW4	CLSPN	O00311	CDC7	S731	G736S	736	Missense	distal	5	no	68.625	68.211	EPSD	TCGA	65.097	Down-regulation
Other_CDC7_CDC7_ST	Q9HAW4	CLSPN	O00311	CDC7	S744	G751D	751	Missense	distal	7	no	76.867	77.210	EPSD;PhosphoSitePlus	TCGA;ICGC	65.097	Up-regulation
Other_CDC7_CDC7_ST	Q9HAW4	CLSPN	O00311	CDC7	T746	G751D	751	Missense	distal	5	no	69.867	69.779	EPSD	TCGA;ICGC	65.097	Down-regulation
Other_CDC7_CDC7_ST	Q9HAW4	CLSPN	O00311	CDC7	S808	P801H	801	Missense	distal	-7	no	69.471	71.354	EPSD	TCGA;COSMIC	65.097	Up-regulation
Other_CDC7_CDC7_ST	Q9HAW4	CLSPN	O00311	CDC7	S808	P801S	801	Missense	distal	-7	no	69.471	66.025	EPSD	TCGA;ICGC;COSMIC	65.097	Down-regulation
Other_CDC7_CDC7_ST	Q9HAW4	CLSPN	O00311	CDC7	S808	P809S	809	Missense	proximal	1	no	69.471	65.160	EPSD	TCGA;COSMIC	65.097	Down-regulation
Other_CDC7_CDC7_ST	Q9HAW4	CLSPN	O00311	CDC7	S808	A803S	803	Missense	distal	-5	no	69.471	66.402	EPSD	TCGA;COSMIC	65.097	Down-regulation
Other_CDC7_CDC7_ST	Q9HAW4	CLSPN	O00311	CDC7	S825	S826L	826	Missense	proximal	1	no	67.509	50.241	EPSD	TCGA;COSMIC	65.097	Loss
Other_CDC7_CDC7_ST	Q9HAW4	CLSPN	O00311	CDC7	S921	Q922E	922	Missense	proximal	1	no	60.720	72.016	EPSD	TCGA;ICGC;COSMIC	65.097	Gain
Other_CDC7_CDC7_ST	Q9HAW4	CLSPN	O00311	CDC7	S968	E967K	967	Missense	proximal	-1	no	69.915	67.044	EPSD	TCGA	65.097	Down-regulation
Other_CDC7_CDC7_ST	Q9HAW4	CLSPN	O00311	CDC7	S1129	R1134Q	1134	Missense	distal	5	no	85.366	85.296	PhosphoSitePlus;EPSD	TCGA;ICGC;COSMIC	65.097	Down-regulation
Other_CDC7_CDC7_ST	Q9HAW4	CLSPN	O00311	CDC7	S1147	D1145G	1145	Missense	proximal	-2	no	74.085	75.276	EPSD;PhosphoSitePlus	TCGA;COSMIC	65.097	Up-regulation
Other_CDC7_CDC7_ST	Q9HAW4	CLSPN	O00311	CDC7	S1147	D1144Y	1144	Missense	distal	-3	no	74.085	74.323	EPSD;PhosphoSitePlus	TCGA	65.097	Up-regulation
Other_CDC7_CDC7_ST	Q9HAW4	CLSPN	O00311	CDC7	S1314	S1310C	1310	Missense	distal	-4	no	69.667	69.583	EPSD	TCGA;COSMIC	65.097	Down-regulation
Other_CDC7_CDC7_ST	Q9HAW4	CLSPN	O00311	CDC7	S1314	S1314Y	1314	Missense	central	0	yes	69.667	0.000	EPSD	TCGA;COSMIC	65.097	Loss
Other_CDC7_CDC7_ST	Q8TEA8	DTD1	O00311	CDC7	S205	G198R	198	Missense	distal	-7	no	67.939	67.446	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC;GDSC;CCLE	65.097	Down-regulation
Other_CDC7_CDC7_ST	Q8TEA8	DTD1	O00311	CDC7	S205	E206A	206	Missense	proximal	1	no	67.939	46.409	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	65.097	Loss
Other_CDC7_CDC7_ST	Q8TEA8	DTD1	O00311	CDC7	S205	D202E	202	Missense	distal	-3	no	67.939	67.835	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	65.097	Down-regulation
Other_CDC7_CDC7_ST	Q8TEA8	DTD1	O00311	CDC7	S205	V203M	203	Missense	proximal	-2	no	67.939	66.243	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	65.097	Down-regulation
Other_CDC7_CDC7_ST	P11388	TOP2A	O00311	CDC7	S1213	R1215H	1215	Missense	proximal	2	no	78.221	74.451	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	65.097	Down-regulation
Other_CDC7_CDC7_ST	P11388	TOP2A	O00311	CDC7	S1213	E1209D	1209	Missense	distal	-4	no	78.221	77.827	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	65.097	Down-regulation
Other_CDC7_CDC7_ST	P11388	TOP2A	O00311	CDC7	S1247	E1242D	1242	Missense	distal	-5	no	63.377	66.400	EPSD	TCGA;ICGC;COSMIC	65.097	Gain
Other_CDC7_CDC7_ST	P11388	TOP2A	O00311	CDC7	S1295	K1289N	1289	Missense	distal	-6	no	64.691	65.336	EPSD	TCGA;ICGC;COSMIC	65.097	Gain
Other_CDC7_CDC7_ST	P11388	TOP2A	O00311	CDC7	S1354	P1350L	1350	Missense	distal	-4	no	67.328	68.397	EPSD	TCGA	65.097	Up-regulation
Other_CDC7_CDC7_ST	P11388	TOP2A	O00311	CDC7	S1377	E1380K	1380	Missense	distal	3	no	66.952	66.698	EPSD	TCGA;ICGC;COSMIC;GDSC;CCLE	65.097	Down-regulation
Other_CDC7_CDC7_ST	P11388	TOP2A	O00311	CDC7	S1377	D1382H	1382	Missense	distal	5	no	66.952	67.497	EPSD	TCGA;ICGC;COSMIC	65.097	Up-regulation
Other_CDC7_CDC7_ST	P11388	TOP2A	O00311	CDC7	S1452	Q1453E	1453	Missense	proximal	1	no	54.812	66.107	EPSD	TCGA;ICGC;COSMIC	65.097	Gain
Other_CDC7_CDC7_ST	Q9UBU7	DBF4	O00311	CDC7	S61	K63Q	63	Missense	proximal	2	no	70.711	73.618	EPSD	TCGA;ICGC;COSMIC	65.097	Up-regulation
Other_CDC7_CDC7_ST	Q9UBU7	DBF4	O00311	CDC7	S118	P119H	119	Missense	proximal	1	no	66.103	37.351	EPSD	TCGA;ICGC;COSMIC	65.097	Loss
Other_CDC7_CDC7_ST	Q9UBU7	DBF4	O00311	CDC7	S118	H120D	120	Missense	proximal	2	no	66.103	68.076	EPSD	TCGA;ICGC	65.097	Up-regulation
Other_CDC7_CDC7_ST	Q9UBU7	DBF4	O00311	CDC7	S118	P119S	119	Missense	proximal	1	no	66.103	61.792	EPSD	TCGA;ICGC;COSMIC	65.097	Loss
Other_CDC7_CDC7_ST	Q9UBU7	DBF4	O00311	CDC7	T194	K190N	190	Missense	distal	-4	no	75.044	76.039	EPSD	TCGA;ICGC;COSMIC	65.097	Up-regulation
Other_CDC7_CDC7_ST	Q9UBU7	DBF4	O00311	CDC7	S195	K190N	190	Missense	distal	-5	no	71.299	74.795	EPSD	TCGA;ICGC;COSMIC	65.097	Up-regulation
Other_CDC7_CDC7_ST	Q9UBU7	DBF4	O00311	CDC7	S259	V255I	255	Missense	distal	-4	no	82.872	82.103	EPSD	TCGA;ICGC	65.097	Down-regulation
Other_CDC7_CDC7_ST	Q9UBU7	DBF4	O00311	CDC7	S259	P252S	252	Missense	distal	-7	no	82.872	79.427	EPSD	TCGA;ICGC;COSMIC	65.097	Down-regulation
Other_CDC7_CDC7_ST	Q9UBU7	DBF4	O00311	CDC7	T273	D274N	274	Missense	proximal	1	no	80.590	61.542	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	65.097	Loss
Other_CDC7_CDC7_ST	Q9UBU7	DBF4	O00311	CDC7	T281	D274N	274	Missense	distal	-7	no	71.885	72.331	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	65.097	Up-regulation
Other_CDC7_CDC7_ST	Q9UBU7	DBF4	O00311	CDC7	S312	F318C	318	Missense	distal	6	no	82.990	83.041	PhosphoSitePlus;EPSD	TCGA;ICGC;COSMIC	65.097	Up-regulation
Other_CDC7_CDC7_ST	Q9UBU7	DBF4	O00311	CDC7	S312	E307K	307	Missense	distal	-5	no	82.990	83.979	PhosphoSitePlus;EPSD	TCGA;ICGC;COSMIC	65.097	Up-regulation
Other_CDC7_CDC7_ST	Q9UBU7	DBF4	O00311	CDC7	S312	N317S	317	Missense	distal	5	no	82.990	82.442	PhosphoSitePlus;EPSD	TCGA;ICGC	65.097	Down-regulation
Other_CDC7_CDC7_ST	Q9UBU7	DBF4	O00311	CDC7	S359	G356V	356	Missense	distal	-3	no	83.320	83.316	EPSD	TCGA;ICGC	65.097	Down-regulation
Other_CDC7_CDC7_ST	Q9UBU7	DBF4	O00311	CDC7	S359	S359Y	359	Missense	central	0	yes	83.320	0.000	EPSD	TCGA;ICGC;COSMIC	65.097	Loss
Other_CDC7_CDC7_ST	Q9UBU7	DBF4	O00311	CDC7	S508	T510N	510	Missense	proximal	2	no	71.827	68.673	EPSD	TCGA;ICGC	65.097	Down-regulation
Other_CDC7_CDC7_ST	P06748	NPM1	O00311	CDC7	S137	L136F	136	Missense	proximal	-1	no	78.837	77.621	PhosphoSitePlus;EPSD	TCGA;ICGC;COSMIC	65.097	Down-regulation
Other_CDC7_CDC7_ST	P06748	NPM1	O00311	CDC7	S137	I138V	138	Missense	proximal	1	no	78.837	77.191	PhosphoSitePlus;EPSD	TCGA;ICGC;COSMIC;GDSC;CCLE	65.097	Down-regulation
Other_CDC7_CDC7_ST	P06748	NPM1	O00311	CDC7	T199	I196V	196	Missense	distal	-3	no	76.935	76.994	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	65.097	Up-regulation
Other_CDC7_CDC7_ST	P06748	NPM1	O00311	CDC7	S218	D213N	213	Missense	distal	-5	no	67.510	68.973	EPSD	TCGA;ICGC;COSMIC	65.097	Up-regulation
Other_CDC7_CDC7_ST	P06748	NPM1	O00311	CDC7	S218	P216S	216	Missense	proximal	-2	no	67.510	66.293	EPSD	TCGA;ICGC;COSMIC	65.097	Down-regulation
Other_CDC7_CDC7_ST	P06748	NPM1	O00311	CDC7	S254	K257E	257	Missense	distal	3	no	75.517	75.771	EPSD	TCGA;ICGC;COSMIC	65.097	Up-regulation
Other_CDC7_CDC7_ST	O75475	PSIP1	O00311	CDC7	S94	P88S	88	Missense	distal	-6	no	68.045	66.909	EPSD	TCGA;ICGC;COSMIC	65.097	Down-regulation
Other_CDC7_CDC7_ST	O75475	PSIP1	O00311	CDC7	S206	D209G	209	Missense	distal	3	no	95.630	95.405	PhosphoSitePlus	TCGA;ICGC;COSMIC	65.097	Down-regulation
Other_CDC7_CDC7_ST	O75475	PSIP1	O00311	CDC7	S208	D209G	209	Missense	proximal	1	no	73.348	57.234	EPSD	TCGA;ICGC;COSMIC	65.097	Loss
Other_CDC7_CDC7_ST	O75475	PSIP1	O00311	CDC7	T212	D209G	209	Missense	distal	-3	no	68.206	68.359	EPSD	TCGA;ICGC;COSMIC	65.097	Up-regulation
Other_CDC7_CDC7_ST	O75475	PSIP1	O00311	CDC7	S273	D274N	274	Missense	proximal	1	no	66.154	47.106	EPSD	TCGA;ICGC;COSMIC	65.097	Loss
Other_CDC7_CDC7_ST	O75475	PSIP1	O00311	CDC7	S275	D274N	274	Missense	proximal	-1	no	70.158	68.699	EPSD	TCGA;ICGC;COSMIC	65.097	Down-regulation
Other_CDC7_CDC7_ST	O75475	PSIP1	O00311	CDC7	S514	R517T	517	Missense	distal	3	no	68.917	68.777	EPSD	TCGA;ICGC;COSMIC	65.097	Down-regulation
Other_CDC7_CDC7_ST	O75475	PSIP1	O00311	CDC7	S514	K509N	509	Missense	distal	-5	no	68.917	72.413	EPSD	TCGA;ICGC	65.097	Up-regulation
Other_CDC7_CDC7_ST	O75475	PSIP1	O00311	CDC7	S514	K510E	510	Missense	distal	-4	no	68.917	69.204	EPSD	TCGA;ICGC	65.097	Up-regulation
Other_CDC7_CDC7_ST	Q9NS91	RAD18	O00311	CDC7	S99	P100L	100	Missense	proximal	1	no	74.952	53.373	EPSD	TCGA;ICGC;COSMIC	65.097	Loss
Other_CDC7_CDC7_ST	Q9NS91	RAD18	O00311	CDC7	S158	S155R	155	Missense	distal	-3	no	79.534	79.480	EPSD	TCGA;ICGC;COSMIC	65.097	Down-regulation
Other_CDC7_CDC7_ST	Q9NS91	RAD18	O00311	CDC7	S434	I427V	427	Missense	distal	-7	no	75.630	79.019	PhosphoSitePlus	TCGA	65.097	Up-regulation
Other_CDC7_CDC7_ST	Q9NS91	RAD18	O00311	CDC7	S434	S438L	438	Missense	distal	4	no	75.630	75.537	PhosphoSitePlus	TCGA;ICGC;COSMIC	65.097	Down-regulation
Other_CDC7_CDC7_ST	Q9NS91	RAD18	O00311	CDC7	S434	C439Y	439	Missense	distal	5	no	75.630	76.594	PhosphoSitePlus	TCGA;ICGC;COSMIC	65.097	Up-regulation
CMGC_MAPK_JNK_MAPK8_ST	Q01844	EWSR1	P45983-2	MAPK8	T79	T79I	79	Missense	central	0	yes	7.669	0.000	PhosphoSitePlus	TCGA;ICGC;COSMIC	2.638	Loss
CMGC_GSK_GSK3B_ST	P11388	TOP2A	P49841	GSK3B	S452	G448V	448	Missense	distal	-4	no	6.040	5.234	EPSD	TCGA;ICGC;COSMIC	6.007	Loss
CMGC_GSK_GSK3B_ST	P11388	TOP2A	P49841	GSK3B	S452	T456M	456	Missense	distal	4	no	6.040	4.674	EPSD	TCGA;ICGC;COSMIC;GDSC	6.007	Loss
CMGC_GSK_GSK3B_ST	P11388	TOP2A	P49841	GSK3B	T950	N945I	945	Missense	distal	-5	no	6.650	7.414	EPSD	TCGA	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	P11388	TOP2A	P49841	GSK3B	T950	T955A	955	Missense	distal	5	no	6.650	6.598	EPSD	TCGA;ICGC;COSMIC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	P11388	TOP2A	P49841	GSK3B	T950	E948G	948	Missense	proximal	-2	no	6.650	6.635	EPSD	TCGA;ICGC;COSMIC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	P11388	TOP2A	P49841	GSK3B	T950	E948D	948	Missense	proximal	-2	no	6.650	6.737	EPSD	TCGA;ICGC	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	P11388	TOP2A	P49841	GSK3B	S1115	S1117C	1117	Missense	proximal	2	no	6.522	6.030	EPSD	TCGA;ICGC;COSMIC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	P11388	TOP2A	P49841	GSK3B	S1115	D1116N	1116	Missense	proximal	1	no	6.522	4.106	EPSD	TCGA;ICGC;COSMIC	6.007	Loss
CMGC_GSK_GSK3B_ST	P11388	TOP2A	P49841	GSK3B	S1115	S1117F	1117	Missense	proximal	2	no	6.522	6.177	EPSD	TCGA;ICGC;COSMIC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	P11388	TOP2A	P49841	GSK3B	S1115	D1120Y	1120	Missense	distal	5	no	6.522	5.417	EPSD	TCGA;ICGC	6.007	Loss
CMGC_GSK_GSK3B_ST	P11388	TOP2A	P49841	GSK3B	S1213	R1215H	1215	Missense	proximal	2	no	7.648	7.305	EPSD	TCGA;ICGC;COSMIC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	P11388	TOP2A	P49841	GSK3B	S1213	E1209D	1209	Missense	distal	-4	no	7.648	7.645	EPSD	TCGA;ICGC;COSMIC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	P11388	TOP2A	P49841	GSK3B	S1247	E1245K	1245	Missense	proximal	-2	no	7.143	7.112	EPSD	TCGA;ICGC;COSMIC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	P11388	TOP2A	P49841	GSK3B	S1247	E1242G	1242	Missense	distal	-5	no	7.143	7.179	EPSD	TCGA;ICGC;COSMIC	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	P11388	TOP2A	P49841	GSK3B	S1247	E1242D	1242	Missense	distal	-5	no	7.143	6.985	EPSD	TCGA;ICGC;COSMIC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	P11388	TOP2A	P49841	GSK3B	S1354	P1350L	1350	Missense	distal	-4	no	9.605	8.819	EPSD	TCGA	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	P11388	TOP2A	P49841	GSK3B	S1361	E1368Q	1368	Missense	distal	7	no	10.106	10.157	PhosphoSitePlus	TCGA;ICGC;COSMIC	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	P11388	TOP2A	P49841	GSK3B	S1387	E1380K	1380	Missense	distal	-7	no	6.530	6.519	EPSD	TCGA;ICGC;COSMIC;GDSC;CCLE	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	P11388	TOP2A	P49841	GSK3B	S1387	D1382H	1382	Missense	distal	-5	no	6.530	6.424	EPSD	TCGA;ICGC;COSMIC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	P36956	SREBF1	P49841	GSK3B	T426	T419I	419	Missense	distal	-7	no	10.176	10.177	EPSD;PhosphoSitePlus	TCGA;COSMIC	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	P36956	SREBF1	P49841	GSK3B	T426	V421A	421	Missense	distal	-5	no	10.176	9.874	EPSD;PhosphoSitePlus	TCGA	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	P36956	SREBF1	P49841	GSK3B	S453	P459L	459	Missense	distal	6	no	9.040	9.033	EPSD	TCGA	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	P36956	SREBF1	P49841	GSK3B	S457	P459L	459	Missense	proximal	2	no	7.730	7.346	EPSD	TCGA	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	P36956	SREBF1	P49841	GSK3B	S461	P459L	459	Missense	proximal	-2	no	8.348	8.017	EPSD	TCGA	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	P10636	MAPT	P49841	GSK3B	S46	T52I	52	Missense	distal	6	no	9.947	9.944	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	P10636	MAPT	P49841	GSK3B	S46	P47S	47	Missense	proximal	1	no	9.947	6.102	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	P10636	MAPT	P49841	GSK3B	S46	P47L	47	Missense	proximal	1	no	9.947	7.086	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	P10636	MAPT	P49841	GSK3B	S46	G42C	42	Missense	distal	-4	no	9.947	8.261	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	P10636	MAPT	P49841	GSK3B	T50	D54E	54	Missense	distal	4	no	9.345	9.748	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	P10636	MAPT	P49841	GSK3B	T50	T52I	52	Missense	proximal	2	no	9.345	9.280	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	P10636	MAPT	P49841	GSK3B	T50	P47S	47	Missense	distal	-3	no	9.345	9.462	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	P10636	MAPT	P49841	GSK3B	T50	P47L	47	Missense	distal	-3	no	9.345	9.472	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	P10636	MAPT	P49841	GSK3B	T50	G55R	55	Missense	distal	5	no	9.345	9.619	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	P10636	MAPT	P49841	GSK3B	T52	P47S	47	Missense	distal	-5	no	5.925	6.082	EPSD	TCGA;ICGC;COSMIC	6.007	Gain
CMGC_GSK_GSK3B_ST	P10636	MAPT	P49841	GSK3B	T52	P47L	47	Missense	distal	-5	no	5.925	6.190	EPSD	TCGA;ICGC;COSMIC	6.007	Gain
CMGC_GSK_GSK3B_ST	P10636	MAPT	P49841	GSK3B	S56	G60S	60	Missense	distal	4	no	2.933	6.176	EPSD	TCGA;ICGC;COSMIC	6.007	Gain
CMGC_GSK_GSK3B_ST	P10636	MAPT	P49841	GSK3B	S64	P59T	59	Missense	distal	-5	no	5.721	6.167	EPSD	TCGA;ICGC;COSMIC	6.007	Gain
CMGC_GSK_GSK3B_ST	P10636	MAPT	P49841	GSK3B	S64	G60S	60	Missense	distal	-4	no	5.721	6.150	EPSD	TCGA;ICGC;COSMIC	6.007	Gain
CMGC_GSK_GSK3B_ST	P10636	MAPT	P49841	GSK3B	S68	A72V	72	Missense	distal	4	no	6.933	6.954	EPSD	TCGA;ICGC;COSMIC	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	P10636	MAPT	P49841	GSK3B	S68	A66S	66	Missense	proximal	-2	no	6.933	7.267	EPSD	TCGA;ICGC;COSMIC	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	P10636	MAPT	P49841	GSK3B	T69	A72V	72	Missense	distal	3	no	6.768	6.897	EPSD	TCGA;ICGC;COSMIC	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	P10636	MAPT	P49841	GSK3B	T69	A66S	66	Missense	distal	-3	no	6.768	6.747	EPSD	TCGA;ICGC;COSMIC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	P10636	MAPT	P49841	GSK3B	T111	A118V	118	Missense	distal	7	no	8.413	8.491	EPSD	TCGA;ICGC;COSMIC	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	P10636	MAPT	P49841	GSK3B	T167	R168H	168	Missense	proximal	1	no	7.072	5.692	EPSD	TCGA;ICGC;COSMIC	6.007	Loss
CMGC_GSK_GSK3B_ST	P10636	MAPT	P49841	GSK3B	T167	R168C	168	Missense	proximal	1	no	7.072	5.069	EPSD	TCGA;ICGC;COSMIC	6.007	Loss
CMGC_GSK_GSK3B_ST	P10636	MAPT	P49841	GSK3B	S171	R168H	168	Missense	distal	-3	no	6.238	6.182	EPSD	TCGA;ICGC;COSMIC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	P10636	MAPT	P49841	GSK3B	S171	R168C	168	Missense	distal	-3	no	6.238	6.173	EPSD	TCGA;ICGC;COSMIC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	P10636	MAPT	P49841	GSK3B	S228	S232Y	232	Missense	distal	4	no	11.620	8.107	EPSD	TCGA;ICGC;COSMIC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	P10636	MAPT	P49841	GSK3B	S228	D223Y	223	Missense	distal	-5	no	11.620	12.000	EPSD	TCGA;ICGC;COSMIC	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	P10636	MAPT	P49841	GSK3B	S228	S227F	227	Missense	proximal	-1	no	11.620	11.489	EPSD	TCGA;ICGC;COSMIC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	P10636	MAPT	P49841	GSK3B	S228	P234L	234	Missense	distal	6	no	11.620	11.613	EPSD	TCGA;ICGC;COSMIC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	P10636	MAPT	P49841	GSK3B	S232	S232Y	232	Missense	central	0	yes	6.264	0.000	EPSD	TCGA;ICGC;COSMIC	6.007	Loss
CMGC_GSK_GSK3B_ST	P10636	MAPT	P49841	GSK3B	S232	S227F	227	Missense	distal	-5	no	6.264	6.824	EPSD	TCGA;ICGC;COSMIC	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	P10636	MAPT	P49841	GSK3B	S232	P234L	234	Missense	proximal	2	no	6.264	5.880	EPSD	TCGA;ICGC;COSMIC	6.007	Loss
CMGC_GSK_GSK3B_ST	P10636	MAPT	P49841	GSK3B	S238	S232Y	232	Missense	distal	-6	no	7.281	7.194	EPSD	TCGA;ICGC;COSMIC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	P10636	MAPT	P49841	GSK3B	S238	A240T	240	Missense	proximal	2	no	7.281	7.399	EPSD	TCGA;ICGC;COSMIC	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	P10636	MAPT	P49841	GSK3B	S238	P234L	234	Missense	distal	-4	no	7.281	6.494	EPSD	TCGA;ICGC;COSMIC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	P10636	MAPT	P49841	GSK3B	S238	R244Q	244	Missense	distal	6	no	7.281	7.282	EPSD	TCGA;ICGC;COSMIC	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	P10636	MAPT	P49841	GSK3B	T386	G387R	387	Missense	proximal	1	no	5.352	6.226	EPSD	TCGA;COSMIC	6.007	Gain
CMGC_GSK_GSK3B_ST	P10636	MAPT	P49841	GSK3B	T416	P415L	415	Missense	proximal	-1	no	9.074	8.943	EPSD	TCGA;ICGC;COSMIC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	P10636	MAPT	P49841	GSK3B	S438	P436T	436	Missense	proximal	-2	no	6.877	6.648	EPSD	TCGA;ICGC;COSMIC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	P10636	MAPT	P49841	GSK3B	S438	P436L	436	Missense	proximal	-2	no	6.877	6.546	EPSD	TCGA;ICGC;COSMIC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	P10636	MAPT	P49841	GSK3B	S438	K440E	440	Missense	proximal	2	no	6.877	6.837	EPSD	TCGA;ICGC;COSMIC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	P10636	MAPT	P49841	GSK3B	S438	S443F	443	Missense	distal	5	no	6.877	6.210	EPSD	TCGA;ICGC;COSMIC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	P10636	MAPT	P49841	GSK3B	S438	V431L	431	Missense	distal	-7	no	6.877	6.856	EPSD	TCGA;ICGC;COSMIC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	P10636	MAPT	P49841	GSK3B	S438	S444F	444	Missense	distal	6	no	6.877	6.865	EPSD	TCGA;ICGC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	P10636	MAPT	P49841	GSK3B	S447	K440E	440	Missense	distal	-7	no	9.392	9.403	EPSD	TCGA;ICGC;COSMIC	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	P10636	MAPT	P49841	GSK3B	S447	S452C	452	Missense	distal	5	no	9.392	8.152	EPSD	TCGA;ICGC;COSMIC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	P10636	MAPT	P49841	GSK3B	S447	S443F	443	Missense	distal	-4	no	9.392	8.238	EPSD	TCGA;ICGC;COSMIC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	P10636	MAPT	P49841	GSK3B	S447	S444F	444	Missense	distal	-3	no	9.392	9.459	EPSD	TCGA;ICGC	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	P10636	MAPT	P49841	GSK3B	S447	S452Y	452	Missense	distal	5	no	9.392	8.393	EPSD	TCGA;ICGC;COSMIC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	P10636	MAPT	P49841	GSK3B	T470	R472Q	472	Missense	proximal	2	no	6.449	6.654	EPSD	TCGA	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	P10636	MAPT	P49841	GSK3B	T470	R472W	472	Missense	proximal	2	no	6.449	6.020	EPSD	TCGA;COSMIC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	P10636	MAPT	P49841	GSK3B	T498	P493Q	493	Missense	distal	-5	no	9.030	9.329	EPSD	TCGA;COSMIC	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	Q8N122	RPTOR	P49841	GSK3B	T706	C713F	713	Missense	distal	7	no	7.306	6.991	EPSD	TCGA	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	Q8N122	RPTOR	P49841	GSK3B	T706	R709Q	709	Missense	distal	3	no	7.306	7.639	EPSD	TCGA;COSMIC	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	Q8N122	RPTOR	P49841	GSK3B	S711	C713F	713	Missense	proximal	2	no	6.809	6.957	EPSD	TCGA	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	Q8N122	RPTOR	P49841	GSK3B	S711	R709Q	709	Missense	proximal	-2	no	6.809	6.880	EPSD	TCGA;COSMIC	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	Q8N122	RPTOR	P49841	GSK3B	T714	S719F	719	Missense	distal	5	no	6.633	5.966	EPSD	TCGA;ICGC;COSMIC	6.007	Loss
CMGC_GSK_GSK3B_ST	Q8N122	RPTOR	P49841	GSK3B	T714	C713F	713	Missense	proximal	-1	no	6.633	6.539	EPSD	TCGA	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	Q8N122	RPTOR	P49841	GSK3B	T714	R709Q	709	Missense	distal	-5	no	6.633	6.078	EPSD	TCGA;COSMIC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	Q8N122	RPTOR	P49841	GSK3B	S738	N741S	741	Missense	distal	3	no	6.617	6.569	EPSD	TCGA	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	Q8N122	RPTOR	P49841	GSK3B	S771	E775K	775	Missense	distal	4	no	10.004	8.822	EPSD	TCGA;COSMIC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	Q8N122	RPTOR	P49841	GSK3B	S855	T857M	857	Missense	proximal	2	no	7.438	6.740	EPSD	TCGA;COSMIC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	Q8N122	RPTOR	P49841	GSK3B	S859	T857M	857	Missense	proximal	-2	no	8.586	8.228	PhosphoSitePlus;EPSD	TCGA;COSMIC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	Q8N122	RPTOR	P49841	GSK3B	S863	T857M	857	Missense	distal	-6	no	8.183	8.188	EPSD;PhosphoSitePlus	TCGA;COSMIC	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	Q8N122	RPTOR	P49841	GSK3B	S877	S877F	877	Missense	central	0	yes	10.498	0.000	EPSD;PhosphoSitePlus	TCGA;COSMIC	6.007	Loss
CMGC_GSK_GSK3B_ST	Q8N122	RPTOR	P49841	GSK3B	S877	P879L	879	Missense	proximal	2	no	10.498	10.113	EPSD;PhosphoSitePlus	TCGA;COSMIC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	Q8N122	RPTOR	P49841	GSK3B	S881	S877F	877	Missense	distal	-4	no	7.749	6.595	EPSD	TCGA;COSMIC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	Q8N122	RPTOR	P49841	GSK3B	S881	P879L	879	Missense	proximal	-2	no	7.749	7.418	EPSD	TCGA;COSMIC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	Q8N122	RPTOR	P49841	GSK3B	S882	S877F	877	Missense	distal	-5	no	6.772	7.331	EPSD	TCGA;COSMIC	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	Q8N122	RPTOR	P49841	GSK3B	S882	P879L	879	Missense	distal	-3	no	6.772	6.898	EPSD	TCGA;COSMIC	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	Q13541	EIF4EBP1	P49841	GSK3B	S83	S86N	86	Missense	distal	3	no	7.700	7.748	EPSD	TCGA;ICGC;COSMIC	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	Q13541	EIF4EBP1	P49841	GSK3B	S101	A107V	107	Missense	distal	6	no	6.885	6.877	EPSD	TCGA;ICGC;COSMIC;GDSC;CCLE	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	P50895	BCAM	P49841	GSK3B	S206	T205N	205	Missense	proximal	-1	no	6.864	7.001	EPSD	TCGA;ICGC;COSMIC	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	P50895	BCAM	P49841	GSK3B	S206	R207H	207	Missense	proximal	1	no	6.864	5.484	EPSD	TCGA;ICGC;COSMIC	6.007	Loss
CMGC_GSK_GSK3B_ST	P50895	BCAM	P49841	GSK3B	S206	R210W	210	Missense	distal	4	no	6.864	5.953	EPSD	TCGA;ICGC;COSMIC	6.007	Loss
CMGC_GSK_GSK3B_ST	P50895	BCAM	P49841	GSK3B	S296	P299L	299	Missense	distal	3	no	6.134	5.816	EPSD	TCGA;ICGC;COSMIC	6.007	Loss
CMGC_GSK_GSK3B_ST	P50895	BCAM	P49841	GSK3B	S541	A547D	547	Missense	distal	6	no	9.231	9.226	EPSD	TCGA;ICGC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	P50895	BCAM	P49841	GSK3B	S596	E592K	592	Missense	distal	-4	no	6.700	6.433	PhosphoSitePlus	TCGA;ICGC;COSMIC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	P50895	BCAM	P49841	GSK3B	S596	E601G	601	Missense	distal	5	no	6.700	6.434	PhosphoSitePlus	TCGA;ICGC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	Q9UPN3	MACF1	P49841	GSK3B	S31	R30W	30	Missense	proximal	-1	no	6.399	6.511	EPSD	TCGA;ICGC;COSMIC	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	Q9UPN3	MACF1	P49841	GSK3B	S31	R24Q	24	Missense	distal	-7	no	6.399	6.396	EPSD	TCGA;ICGC;COSMIC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	Q9UPN3	MACF1	P49841	GSK3B	S31	P36S	36	Missense	distal	5	no	6.399	5.445	EPSD	TCGA;ICGC;COSMIC	6.007	Loss
CMGC_GSK_GSK3B_ST	Q9UPN3	MACF1	P49841	GSK3B	S31	E29K	29	Missense	proximal	-2	no	6.399	6.368	EPSD	TCGA;ICGC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	Q9UPN3	MACF1	P49841	GSK3B	S35	R30W	30	Missense	distal	-5	no	7.018	6.762	EPSD	TCGA;ICGC;COSMIC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	Q9UPN3	MACF1	P49841	GSK3B	S35	P36S	36	Missense	proximal	1	no	7.018	3.173	EPSD	TCGA;ICGC;COSMIC	6.007	Loss
CMGC_GSK_GSK3B_ST	Q9UPN3	MACF1	P49841	GSK3B	S35	E29K	29	Missense	distal	-6	no	7.018	7.017	EPSD	TCGA;ICGC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	Q9UPN3	MACF1	P49841	GSK3B	S280	I287V	287	Missense	distal	7	no	6.510	6.600	EPSD	TCGA;ICGC;COSMIC	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	Q9UPN3	MACF1	P49841	GSK3B	S280	D275H	275	Missense	distal	-5	no	6.510	6.405	EPSD	TCGA;ICGC;COSMIC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	Q9UPN3	MACF1	P49841	GSK3B	T334	S338P	338	Missense	distal	4	no	6.277	3.306	EPSD	TCGA;ICGC;COSMIC	6.007	Loss
CMGC_GSK_GSK3B_ST	Q9UPN3	MACF1	P49841	GSK3B	S559	R566Q	566	Missense	distal	7	no	6.119	5.771	EPSD	TCGA;ICGC;COSMIC	6.007	Loss
CMGC_GSK_GSK3B_ST	Q9UPN3	MACF1	P49841	GSK3B	S862	R861C	861	Missense	proximal	-1	no	8.019	8.120	EPSD	TCGA;ICGC;COSMIC	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	Q9UPN3	MACF1	P49841	GSK3B	S862	V856I	856	Missense	distal	-6	no	8.019	8.023	EPSD	TCGA;ICGC;COSMIC;GDSC	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	Q9UPN3	MACF1	P49841	GSK3B	S1077	A1075T	1075	Missense	proximal	-2	no	5.695	6.057	EPSD	TCGA;ICGC;COSMIC;GDSC;CCLE	6.007	Gain
CMGC_GSK_GSK3B_ST	Q9UPN3	MACF1	P49841	GSK3B	S1122	S1127I	1127	Missense	distal	5	no	10.429	9.762	EPSD	TCGA;ICGC;COSMIC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	Q9UPN3	MACF1	P49841	GSK3B	S1122	S1124C	1124	Missense	proximal	2	no	10.429	9.937	EPSD	TCGA;ICGC;COSMIC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	Q9UPN3	MACF1	P49841	GSK3B	S1122	P1123L	1123	Missense	proximal	1	no	10.429	7.568	EPSD	TCGA;ICGC;COSMIC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	Q9UPN3	MACF1	P49841	GSK3B	S1127	R1132P	1132	Missense	distal	5	no	5.782	6.420	EPSD	TCGA;ICGC;COSMIC	6.007	Gain
CMGC_GSK_GSK3B_ST	Q9UPN3	MACF1	P49841	GSK3B	S1363	P1368S	1368	Missense	distal	5	no	7.336	6.382	EPSD	TCGA;ICGC;COSMIC;CCLE	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	Q9UPN3	MACF1	P49841	GSK3B	S1363	S1363L	1363	Missense	central	0	yes	7.336	0.000	EPSD	TCGA;ICGC;COSMIC	6.007	Loss
CMGC_GSK_GSK3B_ST	Q9UPN3	MACF1	P49841	GSK3B	S1363	S1367F	1367	Missense	distal	4	no	7.336	3.721	EPSD	TCGA;ICGC;COSMIC	6.007	Loss
CMGC_GSK_GSK3B_ST	Q9UPN3	MACF1	P49841	GSK3B	S1367	P1368S	1368	Missense	proximal	1	no	8.371	4.526	EPSD	TCGA;ICGC;COSMIC;CCLE	6.007	Loss
CMGC_GSK_GSK3B_ST	Q9UPN3	MACF1	P49841	GSK3B	S1367	S1363L	1363	Missense	distal	-4	no	8.371	7.021	EPSD	TCGA;ICGC;COSMIC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	Q9UPN3	MACF1	P49841	GSK3B	S1367	S1367F	1367	Missense	central	0	yes	8.371	0.000	EPSD	TCGA;ICGC;COSMIC	6.007	Loss
CMGC_GSK_GSK3B_ST	Q00653	NFKB2	P49841	GSK3B	S222	P223L	223	Missense	proximal	1	no	9.574	6.713	EPSD;PhosphoSitePlus	TCGA;ICGC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	Q00653	NFKB2	P49841	GSK3B	S222	G224E	224	Missense	proximal	2	no	9.574	9.745	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	Q00653	NFKB2	P49841	GSK3B	S277	S277F	277	Missense	central	0	yes	6.631	0.000	EPSD	TCGA;ICGC;COSMIC	6.007	Loss
CMGC_GSK_GSK3B_ST	Q00653	NFKB2	P49841	GSK3B	S277	P278L	278	Missense	proximal	1	no	6.631	3.771	EPSD	TCGA;ICGC;COSMIC	6.007	Loss
CMGC_GSK_GSK3B_ST	Q00653	NFKB2	P49841	GSK3B	S277	D280V	280	Missense	distal	3	no	6.631	6.328	EPSD	TCGA;ICGC;COSMIC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	Q00653	NFKB2	P49841	GSK3B	S707	S707L	707	Missense	central	0	yes	10.090	0.000	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	6.007	Loss
CMGC_GSK_GSK3B_ST	Q00653	NFKB2	P49841	GSK3B	S711	S707L	707	Missense	distal	-4	no	7.797	6.447	PhosphoSitePlus;EPSD	TCGA;ICGC;COSMIC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	Q00653	NFKB2	P49841	GSK3B	S713	S707L	707	Missense	distal	-6	no	7.328	7.327	EPSD	TCGA;ICGC;COSMIC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	Q00653	NFKB2	P49841	GSK3B	T732	D735N	735	Missense	distal	3	no	6.277	6.230	EPSD	TCGA;ICGC;COSMIC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	Q00653	NFKB2	P49841	GSK3B	T732	R729Q	729	Missense	distal	-3	no	6.277	6.138	EPSD	TCGA;ICGC;COSMIC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	Q00653	NFKB2	P49841	GSK3B	T759	P757L	757	Missense	proximal	-2	no	6.142	5.812	EPSD	TCGA;ICGC;COSMIC	6.007	Loss
CMGC_GSK_GSK3B_ST	Q00653	NFKB2	P49841	GSK3B	T759	P760L	760	Missense	proximal	1	no	6.142	3.281	EPSD	TCGA;ICGC;COSMIC	6.007	Loss
CMGC_GSK_GSK3B_ST	Q00653	NFKB2	P49841	GSK3B	S762	P757L	757	Missense	distal	-5	no	6.370	6.636	EPSD	TCGA;ICGC;COSMIC	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	Q00653	NFKB2	P49841	GSK3B	S762	G767A	767	Missense	distal	5	no	6.370	6.253	EPSD	TCGA;ICGC;COSMIC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	Q00653	NFKB2	P49841	GSK3B	S762	P760L	760	Missense	proximal	-2	no	6.370	6.040	EPSD	TCGA;ICGC;COSMIC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	Q00653	NFKB2	P49841	GSK3B	S769	D772G	772	Missense	distal	3	no	7.028	6.977	EPSD	TCGA;ICGC;COSMIC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	Q00653	NFKB2	P49841	GSK3B	S769	D772H	772	Missense	distal	3	no	7.028	6.905	EPSD	TCGA;ICGC;COSMIC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	Q00653	NFKB2	P49841	GSK3B	S769	G767A	767	Missense	proximal	-2	no	7.028	6.811	EPSD	TCGA;ICGC;COSMIC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	Q00653	NFKB2	P49841	GSK3B	T810	G815D	815	Missense	distal	5	no	6.596	6.660	EPSD	TCGA;ICGC;COSMIC	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	Q00653	NFKB2	P49841	GSK3B	S812	G815D	815	Missense	distal	3	no	10.832	10.883	EPSD	TCGA;ICGC;COSMIC	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	Q00653	NFKB2	P49841	GSK3B	S814	G815D	815	Missense	proximal	1	no	6.181	6.272	EPSD	TCGA;ICGC;COSMIC	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	Q00653	NFKB2	P49841	GSK3B	S816	G815D	815	Missense	proximal	-1	no	6.677	6.610	EPSD	TCGA;ICGC;COSMIC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	P58012	FOXL2	P49841	GSK3B	S33	G38S	38	Missense	distal	5	no	7.625	7.583	PhosphoSitePlus	TCGA;ICGC;COSMIC;CCLE	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	P58012	FOXL2	P49841	GSK3B	S211	P212A	212	Missense	proximal	1	no	7.140	3.408	EPSD	TCGA;ICGC;COSMIC	6.007	Loss
CMGC_GSK_GSK3B_ST	O15294	OGT	P49841	GSK3B	S74	R69Q	69	Missense	distal	-5	no	6.379	5.825	EPSD	TCGA;COSMIC	6.007	Loss
CMGC_GSK_GSK3B_ST	O15294	OGT	P49841	GSK3B	T325	H326Y	326	Missense	proximal	1	no	6.046	6.428	EPSD	TCGA;COSMIC	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	O15294	OGT	P49841	GSK3B	S369	A363T	363	Missense	distal	-6	no	6.082	6.013	EPSD	TCGA	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	O15294	OGT	P49841	GSK3B	S1004	Q1011P	1011	Missense	distal	7	no	7.036	6.882	EPSD	TCGA;ICGC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	O15294	OGT	P49841	GSK3B	S1004	P1005L	1005	Missense	proximal	1	no	7.036	4.175	EPSD	TCGA;ICGC	6.007	Loss
CMGC_GSK_GSK3B_ST	Q14449	GRB14	P49841	GSK3B	S20	A23T	23	Missense	distal	3	no	7.492	7.797	EPSD	TCGA;ICGC;COSMIC	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	Q14449	GRB14	P49841	GSK3B	S358	Q363H	363	Missense	distal	5	no	8.048	7.398	EPSD;PhosphoSitePlus	TCGA;COSMIC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	Q14449	GRB14	P49841	GSK3B	S362	Q363H	363	Missense	proximal	1	no	8.428	7.996	PhosphoSitePlus;EPSD	TCGA;COSMIC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	Q14449	GRB14	P49841	GSK3B	S366	E373K	373	Missense	distal	7	no	9.293	9.184	EPSD;PhosphoSitePlus	TCGA;COSMIC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	Q14449	GRB14	P49841	GSK3B	S366	Q363H	363	Missense	distal	-3	no	9.293	9.375	EPSD;PhosphoSitePlus	TCGA;COSMIC	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	Q14449	GRB14	P49841	GSK3B	S419	L414R	414	Missense	distal	-5	no	10.782	11.371	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	Q14449	GRB14	P49841	GSK3B	S419	H417Y	417	Missense	proximal	-2	no	10.782	10.568	EPSD;PhosphoSitePlus	TCGA;COSMIC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	Q14449	GRB14	P49841	GSK3B	S419	S419I	419	Missense	central	0	yes	10.782	0.000	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	6.007	Loss
CMGC_GSK_GSK3B_ST	Q14449	GRB14	P49841	GSK3B	S419	S426I	426	Missense	distal	7	no	10.782	11.118	EPSD;PhosphoSitePlus	TCGA	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	Q14449	GRB14	P49841	GSK3B	S423	H417Y	417	Missense	distal	-6	no	7.814	7.762	EPSD;PhosphoSitePlus	TCGA;COSMIC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	Q14449	GRB14	P49841	GSK3B	S423	S419I	419	Missense	distal	-4	no	7.814	5.331	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	6.007	Loss
CMGC_GSK_GSK3B_ST	Q14449	GRB14	P49841	GSK3B	S423	S426I	426	Missense	distal	3	no	7.814	7.394	EPSD;PhosphoSitePlus	TCGA	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	Q14449	GRB14	P49841	GSK3B	S423	A428D	428	Missense	distal	5	no	7.814	7.995	EPSD;PhosphoSitePlus	TCGA;ICGC	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	P49768	PSEN1	P49841	GSK3B	S59	R60W	60	Missense	proximal	1	no	6.466	6.684	EPSD	TCGA;ICGC	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	P49768	PSEN1	P49841	GSK3B	S353	S346N	346	Missense	distal	-7	no	7.747	7.753	PhosphoSitePlus;EPSD	TCGA	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	P49768	PSEN1	P49841	GSK3B	S353	P355A	355	Missense	proximal	2	no	7.747	7.310	PhosphoSitePlus;EPSD	TCGA;COSMIC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	P49768	PSEN1	P49841	GSK3B	T354	P355A	355	Missense	proximal	1	no	6.842	3.110	EPSD	TCGA;COSMIC	6.007	Loss
CMGC_GSK_GSK3B_ST	P49768	PSEN1	P49841	GSK3B	S357	P355A	355	Missense	proximal	-2	no	8.588	7.997	EPSD;PhosphoSitePlus	TCGA;COSMIC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	P49768	PSEN1	P49841	GSK3B	S357	E363Q	363	Missense	distal	6	no	8.588	8.590	EPSD;PhosphoSitePlus	TCGA;COSMIC	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	O75122	CLASP2	P49841	GSK3B	S364	R369Q	369	Missense	distal	5	no	8.449	8.110	EPSD	TCGA;COSMIC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	O75122	CLASP2	P49841	GSK3B	S368	R369Q	369	Missense	proximal	1	no	6.078	5.130	EPSD	TCGA;COSMIC	6.007	Loss
CMGC_GSK_GSK3B_ST	O75122	CLASP2	P49841	GSK3B	S533	S537I	537	Missense	distal	4	no	9.513	6.191	EPSD;PhosphoSitePlus	TCGA	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	O75122	CLASP2	P49841	GSK3B	S537	S537I	537	Missense	central	0	yes	10.617	0.000	EPSD;PhosphoSitePlus	TCGA	6.007	Loss
CMGC_GSK_GSK3B_ST	O75122	CLASP2	P49841	GSK3B	S541	S537I	537	Missense	distal	-4	no	8.160	5.677	EPSD	TCGA	6.007	Loss
CMGC_GSK_GSK3B_ST	O75122	CLASP2	P49841	GSK3B	T919	D926G	926	Missense	distal	7	no	6.236	6.201	EPSD	TCGA;COSMIC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	O75122	CLASP2	P49841	GSK3B	S921	D926G	926	Missense	distal	5	no	6.073	6.009	EPSD	TCGA;COSMIC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	Q6PGQ7	BORA	P49841	GSK3B	S41	F45L	45	Missense	distal	4	no	5.867	6.763	EPSD	TCGA	6.007	Gain
CMGC_GSK_GSK3B_ST	Q6PGQ7	BORA	P49841	GSK3B	S43	F45L	45	Missense	proximal	2	no	5.954	6.359	EPSD	TCGA	6.007	Gain
CMGC_GSK_GSK3B_ST	Q6PGQ7	BORA	P49841	GSK3B	S112	H117N	117	Missense	distal	5	no	7.110	7.463	EPSD	TCGA;ICGC	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	Q6PGQ7	BORA	P49841	GSK3B	S135	C130Y	130	Missense	distal	-5	no	6.129	6.262	EPSD	TCGA;ICGC	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	Q6PGQ7	BORA	P49841	GSK3B	S229	S229L	229	Missense	central	0	yes	6.354	0.000	EPSD	TCGA;ICGC	6.007	Loss
CMGC_GSK_GSK3B_ST	Q6PGQ7	BORA	P49841	GSK3B	S229	D231Y	231	Missense	proximal	2	no	6.354	6.029	EPSD	TCGA;ICGC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	Q6PGQ7	BORA	P49841	GSK3B	S239	S246L	246	Missense	distal	7	no	9.646	9.631	EPSD	TCGA;ICGC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	Q6PGQ7	BORA	P49841	GSK3B	T243	S246L	246	Missense	distal	3	no	7.362	7.062	EPSD	TCGA;ICGC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	Q6PGQ7	BORA	P49841	GSK3B	S246	S246L	246	Missense	central	0	yes	6.360	0.000	EPSD	TCGA;ICGC	6.007	Loss
CMGC_GSK_GSK3B_ST	Q6PGQ7	BORA	P49841	GSK3B	S252	S257T	257	Missense	distal	5	no	7.365	7.342	EPSD	TCGA;ICGC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	Q6PGQ7	BORA	P49841	GSK3B	S252	S246L	246	Missense	distal	-6	no	7.365	7.363	EPSD	TCGA;ICGC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	Q6PGQ7	BORA	P49841	GSK3B	S268	I272V	272	Missense	distal	4	no	6.184	7.116	EPSD	TCGA;ICGC	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	Q6PGQ7	BORA	P49841	GSK3B	S270	I272V	272	Missense	proximal	2	no	9.887	9.557	EPSD	TCGA;ICGC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	Q6PGQ7	BORA	P49841	GSK3B	S274	I272V	272	Missense	proximal	-2	no	9.910	9.888	EPSD;PhosphoSitePlus	TCGA;ICGC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	Q6PGQ7	BORA	P49841	GSK3B	S274	I280T	280	Missense	distal	6	no	9.910	9.912	EPSD;PhosphoSitePlus	TCGA;ICGC	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	Q6PGQ7	BORA	P49841	GSK3B	S278	I284T	284	Missense	distal	6	no	7.479	7.482	PhosphoSitePlus;EPSD	TCGA;ICGC	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	Q6PGQ7	BORA	P49841	GSK3B	S278	I272V	272	Missense	distal	-6	no	7.479	7.475	PhosphoSitePlus;EPSD	TCGA;ICGC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	Q6PGQ7	BORA	P49841	GSK3B	S278	I280T	280	Missense	proximal	2	no	7.479	7.545	PhosphoSitePlus;EPSD	TCGA;ICGC	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	Q6PGQ7	BORA	P49841	GSK3B	S299	K294T	294	Missense	distal	-5	no	9.391	9.480	EPSD	TCGA;ICGC	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	Q6PGQ7	BORA	P49841	GSK3B	S304	S308F	308	Missense	distal	4	no	6.567	2.952	EPSD	TCGA;ICGC	6.007	Loss
CMGC_GSK_GSK3B_ST	Q6PGQ7	BORA	P49841	GSK3B	S374	T371K	371	Missense	distal	-3	no	6.171	6.169	EPSD	TCGA;ICGC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	Q6PGQ7	BORA	P49841	GSK3B	S374	A377T	377	Missense	distal	3	no	6.171	6.475	EPSD	TCGA;ICGC	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	Q6PGQ7	BORA	P49841	GSK3B	S374	D379N	379	Missense	distal	5	no	6.171	5.744	EPSD	TCGA;ICGC	6.007	Loss
CMGC_GSK_GSK3B_ST	Q6PGQ7	BORA	P49841	GSK3B	S375	T371K	371	Missense	distal	-4	no	8.312	7.783	EPSD	TCGA;ICGC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	Q6PGQ7	BORA	P49841	GSK3B	S375	A377T	377	Missense	proximal	2	no	8.312	8.431	EPSD	TCGA;ICGC	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	Q6PGQ7	BORA	P49841	GSK3B	S375	D379N	379	Missense	distal	4	no	8.312	7.126	EPSD	TCGA;ICGC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	Q6PGQ7	BORA	P49841	GSK3B	T446	D443H	443	Missense	distal	-3	no	7.024	7.090	EPSD	TCGA;ICGC	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	Q6PGQ7	BORA	P49841	GSK3B	T446	E440Q	440	Missense	distal	-6	no	7.024	7.081	EPSD	TCGA;ICGC	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	O95863	SNAI1	P49841	GSK3B	S82	R78Q	78	Missense	distal	-4	no	6.302	6.660	EPSD	TCGA;ICGC;COSMIC	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	O95863	SNAI1	P49841	GSK3B	S104	P110S	110	Missense	distal	6	no	9.476	9.474	PhosphoSitePlus;EPSD	TCGA;ICGC;COSMIC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	O95863	SNAI1	P49841	GSK3B	S107	P110S	110	Missense	distal	3	no	11.906	11.889	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	O95863	SNAI1	P49841	GSK3B	S107	S114F	114	Missense	distal	7	no	11.906	11.984	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	O95863	SNAI1	P49841	GSK3B	S111	P110S	110	Missense	proximal	-1	no	6.721	6.664	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	O95863	SNAI1	P49841	GSK3B	S111	S114F	114	Missense	distal	3	no	6.721	6.510	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	O95863	SNAI1	P49841	GSK3B	S111	S115F	115	Missense	distal	4	no	6.721	3.106	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	6.007	Loss
CMGC_GSK_GSK3B_ST	O95863	SNAI1	P49841	GSK3B	S115	S119F	119	Missense	distal	4	no	6.986	3.371	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	6.007	Loss
CMGC_GSK_GSK3B_ST	O95863	SNAI1	P49841	GSK3B	S115	P110S	110	Missense	distal	-5	no	6.986	7.142	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	O95863	SNAI1	P49841	GSK3B	S115	S114F	114	Missense	proximal	-1	no	6.986	6.855	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	O95863	SNAI1	P49841	GSK3B	S115	S115F	115	Missense	central	0	yes	6.986	0.000	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	6.007	Loss
CMGC_GSK_GSK3B_ST	O95863	SNAI1	P49841	GSK3B	S246	R247P	247	Missense	proximal	1	no	3.718	6.038	EPSD	TCGA;ICGC;COSMIC	6.007	Gain
CMGC_GSK_GSK3B_ST	P19793	RXRA	P49841	GSK3B	S17	Q14K	14	Missense	distal	-3	no	7.134	7.128	EPSD	TCGA;ICGC;COSMIC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	P19793	RXRA	P49841	GSK3B	S17	Q14L	14	Missense	distal	-3	no	7.134	7.114	EPSD	TCGA;ICGC;COSMIC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	P19793	RXRA	P49841	GSK3B	S21	S27C	27	Missense	distal	6	no	6.940	6.927	EPSD	TCGA;ICGC;COSMIC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	P19793	RXRA	P49841	GSK3B	S21	Q14K	14	Missense	distal	-7	no	6.940	6.946	EPSD	TCGA;ICGC;COSMIC	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	P19793	RXRA	P49841	GSK3B	S21	Q14L	14	Missense	distal	-7	no	6.940	6.925	EPSD	TCGA;ICGC;COSMIC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	P19793	RXRA	P49841	GSK3B	S49	L47V	47	Missense	proximal	-2	no	9.069	9.110	PhosphoSitePlus;EPSD	TCGA;ICGC;COSMIC	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	P19793	RXRA	P49841	GSK3B	S49	S43F	43	Missense	distal	-6	no	9.069	9.015	PhosphoSitePlus;EPSD	TCGA;ICGC;COSMIC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	P19793	RXRA	P49841	GSK3B	S66	V67F	67	Missense	proximal	1	no	7.961	6.720	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	P19793	RXRA	P49841	GSK3B	S66	N59S	59	Missense	distal	-7	no	7.961	7.955	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	P19793	RXRA	P49841	GSK3B	S66	P63L	63	Missense	distal	-3	no	7.961	8.087	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	P19793	RXRA	P49841	GSK3B	S78	S78L	78	Missense	central	0	yes	7.260	0.000	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	6.007	Loss
CMGC_GSK_GSK3B_ST	P19793	RXRA	P49841	GSK3B	S78	M77V	77	Missense	proximal	-1	no	7.260	7.359	EPSD;PhosphoSitePlus	TCGA;ICGC	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	P19793	RXRA	P49841	GSK3B	T82	S78L	78	Missense	distal	-4	no	6.834	5.484	EPSD	TCGA;ICGC;COSMIC	6.007	Loss
CMGC_GSK_GSK3B_ST	P19793	RXRA	P49841	GSK3B	T82	M77V	77	Missense	distal	-5	no	6.834	7.112	EPSD	TCGA;ICGC	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	P19793	RXRA	P49841	GSK3B	S260	V265I	265	Missense	distal	5	no	6.299	6.133	EPSD	TCGA	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	P19793	RXRA	P49841	GSK3B	S260	G255W	255	Missense	distal	-5	no	6.299	6.273	EPSD	TCGA;ICGC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	P05412	JUN	P49841	GSK3B	S73	S73L	73	Missense	central	0	yes	7.671	0.000	EPSD	TCGA;ICGC;COSMIC	6.007	Loss
CMGC_GSK_GSK3B_ST	P05412	JUN	P49841	GSK3B	T91	G86W	86	Missense	distal	-5	no	8.831	8.806	EPSD	TCGA;ICGC;COSMIC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	P05412	JUN	P49841	GSK3B	T93	G86W	86	Missense	distal	-7	no	6.874	6.904	EPSD	TCGA;ICGC;COSMIC	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	P05412	JUN	P49841	GSK3B	T93	C99Y	99	Missense	distal	6	no	6.874	6.882	EPSD	TCGA;ICGC;COSMIC	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	P05412	JUN	P49841	GSK3B	T239	P244L	244	Missense	distal	5	no	10.446	9.165	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	P05412	JUN	P49841	GSK3B	S243	P244L	244	Missense	proximal	1	no	8.558	5.697	PhosphoSitePlus;EPSD	TCGA;ICGC;COSMIC	6.007	Loss
CMGC_GSK_GSK3B_ST	Q9UMX1	SUFU	P49841	GSK3B	S342	R339W	339	Missense	distal	-3	no	7.675	7.606	PhosphoSitePlus	TCGA;COSMIC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	Q9UMX1	SUFU	P49841	GSK3B	S349	T353M	353	Missense	distal	4	no	6.655	5.289	EPSD	TCGA;ICGC;COSMIC	6.007	Loss
CMGC_GSK_GSK3B_ST	O00213	APBB1	P49841	GSK3B	S175	E181D	181	Missense	distal	6	no	8.911	8.909	EPSD	TCGA;ICGC;COSMIC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	O00213	APBB1	P49841	GSK3B	S287	P288L	288	Missense	proximal	1	no	6.458	3.598	EPSD	TCGA;COSMIC	6.007	Loss
CMGC_GSK_GSK3B_ST	O00213	APBB1	P49841	GSK3B	S287	G284V	284	Missense	distal	-3	no	6.458	6.630	EPSD	TCGA	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	O00213	APBB1	P49841	GSK3B	S287	R285W	285	Missense	proximal	-2	no	6.458	6.664	EPSD	TCGA;COSMIC	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	O00213	APBB1	P49841	GSK3B	S287	P288S	288	Missense	proximal	1	no	6.458	2.614	EPSD	TCGA;COSMIC	6.007	Loss
CMGC_GSK_GSK3B_ST	O00213	APBB1	P49841	GSK3B	S287	G284S	284	Missense	distal	-3	no	6.458	6.462	EPSD	TCGA;COSMIC	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	O00213	APBB1	P49841	GSK3B	S289	P288L	288	Missense	proximal	-1	no	7.898	7.766	EPSD	TCGA;COSMIC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	O00213	APBB1	P49841	GSK3B	S289	G284V	284	Missense	distal	-5	no	7.898	8.011	EPSD	TCGA	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	O00213	APBB1	P49841	GSK3B	S289	R285W	285	Missense	distal	-4	no	7.898	7.068	EPSD	TCGA;COSMIC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	O00213	APBB1	P49841	GSK3B	S289	P288S	288	Missense	proximal	-1	no	7.898	7.841	EPSD	TCGA;COSMIC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	O00213	APBB1	P49841	GSK3B	S289	G284S	284	Missense	distal	-5	no	7.898	7.432	EPSD	TCGA;COSMIC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	O00213	APBB1	P49841	GSK3B	S345	A343T	343	Missense	proximal	-2	no	5.717	6.079	EPSD	TCGA;COSMIC	6.007	Gain
CMGC_GSK_GSK3B_ST	O00213	APBB1	P49841	GSK3B	S347	Q353H	353	Missense	distal	6	no	6.995	6.988	EPSD	TCGA;COSMIC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	O00213	APBB1	P49841	GSK3B	S347	Q344H	344	Missense	distal	-3	no	6.995	7.077	EPSD	TCGA;COSMIC	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	O00213	APBB1	P49841	GSK3B	S347	P350L	350	Missense	distal	3	no	6.995	6.676	EPSD	TCGA;COSMIC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	O00213	APBB1	P49841	GSK3B	S347	A343T	343	Missense	distal	-4	no	6.995	7.819	EPSD	TCGA;COSMIC	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	P03372	ESR1	P49841	GSK3B	S106	P113S	113	Missense	distal	7	no	9.203	9.266	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	P03372	ESR1	P49841	GSK3B	S282	M286T	286	Missense	distal	4	no	5.345	6.711	EPSD	TCGA;ICGC;COSMIC	6.007	Gain
CMGC_GSK_GSK3B_ST	P03372	ESR1	P49841	GSK3B	S294	I298M	298	Missense	distal	4	no	5.747	6.834	EPSD	TCGA;ICGC;COSMIC	6.007	Gain
CMGC_GSK_GSK3B_ST	P03372	ESR1	P49841	GSK3B	S305	I298M	298	Missense	distal	-7	no	6.457	6.451	EPSD	TCGA;ICGC;COSMIC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	P03372	ESR1	P49841	GSK3B	S305	A307S	307	Missense	proximal	2	no	6.457	6.450	EPSD	TCGA;ICGC;COSMIC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	P03372	ESR1	P49841	GSK3B	S305	T311M	311	Missense	distal	6	no	6.457	6.450	EPSD	TCGA;ICGC;COSMIC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	P03372	ESR1	P49841	GSK3B	T570	T563M	563	Missense	distal	-7	no	6.049	6.043	EPSD	TCGA;ICGC;COSMIC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	P03372	ESR1	P49841	GSK3B	T570	S575L	575	Missense	distal	5	no	6.049	5.722	EPSD	TCGA;ICGC;COSMIC	6.007	Loss
CMGC_GSK_GSK3B_ST	O95271	TNKS	P49841	GSK3B	T477	A475T	475	Missense	proximal	-2	no	6.547	6.909	EPSD	TCGA;ICGC;COSMIC	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	O95271	TNKS	P49841	GSK3B	T477	T477I	477	Missense	central	0	yes	6.547	0.000	EPSD	TCGA;ICGC;COSMIC	6.007	Loss
CMGC_GSK_GSK3B_ST	O95271	TNKS	P49841	GSK3B	T477	E479K	479	Missense	proximal	2	no	6.547	6.587	EPSD	TCGA;ICGC;COSMIC	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	O95271	TNKS	P49841	GSK3B	T839	D832Y	832	Missense	distal	-7	no	6.423	6.449	EPSD	TCGA;COSMIC	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	O95271	TNKS	P49841	GSK3B	T839	L841M	841	Missense	proximal	2	no	6.423	5.792	EPSD	TCGA;COSMIC	6.007	Loss
CMGC_GSK_GSK3B_ST	O95271	TNKS	P49841	GSK3B	T839	T833I	833	Missense	distal	-6	no	6.423	6.418	EPSD	TCGA;ICGC;COSMIC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	O95271	TNKS	P49841	GSK3B	S978	L976V	976	Missense	proximal	-2	no	9.811	9.853	EPSD;PhosphoSitePlus	TCGA;COSMIC;GDSC	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	O95271	TNKS	P49841	GSK3B	T982	L976V	976	Missense	distal	-6	no	8.175	8.109	PhosphoSitePlus;EPSD	TCGA;COSMIC;GDSC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	Q9NS23	RASSF1	P49841	GSK3B	S179	V175M	175	Missense	distal	-4	no	8.019	8.193	PhosphoSitePlus;EPSD	TCGA;COSMIC	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	O75925	PIAS1	P49841	GSK3B	S50	M55I	55	Missense	distal	5	no	6.842	6.315	EPSD	TCGA;ICGC;COSMIC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	O75925	PIAS1	P49841	GSK3B	S322	T327P	327	Missense	distal	5	no	5.378	6.355	EPSD	TCGA;ICGC	6.007	Gain
CMGC_GSK_GSK3B_ST	O75925	PIAS1	P49841	GSK3B	S328	T327P	327	Missense	proximal	-1	no	5.999	6.130	EPSD	TCGA;ICGC	6.007	Gain
CMGC_GSK_GSK3B_ST	O75925	PIAS1	P49841	GSK3B	S328	S322G	322	Missense	distal	-6	no	5.999	6.015	EPSD	TCGA;ICGC;COSMIC	6.007	Gain
CMGC_GSK_GSK3B_ST	O75925	PIAS1	P49841	GSK3B	S503	S510R	510	Missense	distal	7	no	5.575	6.013	EPSD	TCGA;ICGC	6.007	Gain
CMGC_GSK_GSK3B_ST	O75925	PIAS1	P49841	GSK3B	S503	P499S	499	Missense	distal	-4	no	5.575	6.138	EPSD	TCGA;ICGC;COSMIC	6.007	Gain
CMGC_GSK_GSK3B_ST	O75925	PIAS1	P49841	GSK3B	S506	S510R	510	Missense	distal	4	no	7.611	4.573	EPSD	TCGA;ICGC	6.007	Loss
CMGC_GSK_GSK3B_ST	O75925	PIAS1	P49841	GSK3B	S506	P504L	504	Missense	proximal	-2	no	7.611	7.280	EPSD	TCGA;ICGC;COSMIC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	O75925	PIAS1	P49841	GSK3B	S506	P499S	499	Missense	distal	-7	no	7.611	7.612	EPSD	TCGA;ICGC;COSMIC	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	O75925	PIAS1	P49841	GSK3B	S510	S510R	510	Missense	central	0	yes	6.945	0.000	EPSD	TCGA;ICGC	6.007	Loss
CMGC_GSK_GSK3B_ST	O75925	PIAS1	P49841	GSK3B	S510	P504L	504	Missense	distal	-6	no	6.945	6.923	EPSD	TCGA;ICGC;COSMIC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	O75925	PIAS1	P49841	GSK3B	S517	T521P	521	Missense	distal	4	no	6.679	4.577	EPSD	TCGA	6.007	Loss
CMGC_GSK_GSK3B_ST	O75925	PIAS1	P49841	GSK3B	S517	Y518H	518	Missense	proximal	1	no	6.679	6.297	EPSD	TCGA;ICGC;COSMIC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	O75925	PIAS1	P49841	GSK3B	S517	S510R	510	Missense	distal	-7	no	6.679	6.697	EPSD	TCGA;ICGC	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	O75925	PIAS1	P49841	GSK3B	S522	T521P	521	Missense	proximal	-1	no	6.003	6.134	EPSD	TCGA	6.007	Gain
CMGC_GSK_GSK3B_ST	Q9NZQ7	CD274	P49841	GSK3B	S279	D276H	276	Missense	distal	-3	no	7.625	7.691	EPSD	TCGA;COSMIC	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	Q9NZQ7	CD274	P49841	GSK3B	S279	K280N	280	Missense	proximal	1	no	7.625	5.651	EPSD	TCGA;COSMIC	6.007	Loss
CMGC_GSK_GSK3B_ST	Q9NZQ7	CD274	P49841	GSK3B	S279	T277S	277	Missense	proximal	-2	no	7.625	7.598	EPSD	TCGA;COSMIC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	P0DMV8	HSPA1A	P49841	GSK3B	T38	T37I	37	Missense	proximal	-1	no	6.490	6.415	EPSD	TCGA;ICGC;COSMIC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	P0DMV8	HSPA1A	P49841	GSK3B	T38	G34S	34	Missense	distal	-4	no	6.490	6.918	EPSD	TCGA;ICGC;COSMIC	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	P0DMV8	HSPA1A	P49841	GSK3B	S633	E638K	638	Missense	distal	5	no	6.469	5.602	EPSD	TCGA;ICGC;COSMIC	6.007	Loss
CMGC_GSK_GSK3B_ST	P0DMV8	HSPA1A	P49841	GSK3B	S633	G632V	632	Missense	proximal	-1	no	6.469	6.511	EPSD	TCGA;COSMIC	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	P0DMV8	HSPA1A	P49841	GSK3B	S633	E639D	639	Missense	distal	6	no	6.469	6.468	EPSD	TCGA;COSMIC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	Q14596	NBR1	P49841	GSK3B	S273	H272D	272	Missense	proximal	-1	no	6.780	6.771	EPSD	TCGA;ICGC;COSMIC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	Q14596	NBR1	P49841	GSK3B	S273	S276C	276	Missense	distal	3	no	6.780	6.564	EPSD	TCGA;ICGC;COSMIC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	Q14596	NBR1	P49841	GSK3B	S273	P269S	269	Missense	distal	-4	no	6.780	7.343	EPSD	TCGA;ICGC;COSMIC	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	Q14596	NBR1	P49841	GSK3B	S273	S267A	267	Missense	distal	-6	no	6.780	6.790	EPSD	TCGA;ICGC;COSMIC	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	Q14596	NBR1	P49841	GSK3B	S273	P269L	269	Missense	distal	-4	no	6.780	5.993	EPSD	TCGA;ICGC;COSMIC	6.007	Loss
CMGC_GSK_GSK3B_ST	Q14596	NBR1	P49841	GSK3B	S340	P344S	344	Missense	distal	4	no	5.283	8.254	EPSD	TCGA;ICGC;COSMIC	6.007	Gain
CMGC_GSK_GSK3B_ST	Q14596	NBR1	P49841	GSK3B	S486	P482S	482	Missense	distal	-4	no	5.717	6.281	EPSD	TCGA;ICGC;COSMIC	6.007	Gain
CMGC_GSK_GSK3B_ST	Q14596	NBR1	P49841	GSK3B	T581	P582S	582	Missense	proximal	1	no	6.430	2.586	EPSD	TCGA;ICGC	6.007	Loss
CMGC_GSK_GSK3B_ST	Q14596	NBR1	P49841	GSK3B	T581	P582H	582	Missense	proximal	1	no	6.430	2.730	EPSD	TCGA;ICGC;COSMIC	6.007	Loss
CMGC_GSK_GSK3B_ST	Q14596	NBR1	P49841	GSK3B	T581	T586I	586	Missense	distal	5	no	6.430	5.787	EPSD	TCGA;ICGC;COSMIC	6.007	Loss
CMGC_GSK_GSK3B_ST	Q14596	NBR1	P49841	GSK3B	T586	P582S	582	Missense	distal	-4	no	10.220	10.783	PhosphoSitePlus	TCGA;ICGC	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	Q14596	NBR1	P49841	GSK3B	T586	P582H	582	Missense	distal	-4	no	10.220	9.695	PhosphoSitePlus	TCGA;ICGC;COSMIC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	Q14596	NBR1	P49841	GSK3B	T586	T586I	586	Missense	central	0	yes	10.220	0.000	PhosphoSitePlus	TCGA;ICGC;COSMIC	6.007	Loss
CMGC_GSK_GSK3B_ST	Q14596	NBR1	P49841	GSK3B	S590	T586I	586	Missense	distal	-4	no	6.747	4.599	EPSD	TCGA;ICGC;COSMIC	6.007	Loss
CMGC_GSK_GSK3B_ST	Q14596	NBR1	P49841	GSK3B	S673	C669Y	669	Missense	distal	-4	no	5.057	6.371	EPSD	TCGA;ICGC;COSMIC	6.007	Gain
CMGC_GSK_GSK3B_ST	Q14596	NBR1	P49841	GSK3B	T841	E844K	844	Missense	distal	3	no	6.065	5.958	EPSD	TCGA;ICGC	6.007	Loss
CMGC_GSK_GSK3B_ST	Q14596	NBR1	P49841	GSK3B	S891	S891F	891	Missense	central	0	yes	6.696	0.000	EPSD	TCGA;ICGC;COSMIC;GDSC;CCLE	6.007	Loss
CMGC_GSK_GSK3B_ST	Q14596	NBR1	P49841	GSK3B	S891	S895F	895	Missense	distal	4	no	6.696	3.082	EPSD	TCGA;ICGC	6.007	Loss
CMGC_GSK_GSK3B_ST	P12036	NEFH	P49841	GSK3B	S337	E331K	331	Missense	distal	-6	no	6.961	6.960	EPSD	TCGA;ICGC;COSMIC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	P12036	NEFH	P49841	GSK3B	S337	E331Q	331	Missense	distal	-6	no	6.961	7.018	EPSD	TCGA;ICGC;COSMIC	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	P12036	NEFH	P49841	GSK3B	S337	K336E	336	Missense	proximal	-1	no	6.961	6.894	EPSD	TCGA;ICGC;COSMIC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	P12036	NEFH	P49841	GSK3B	S337	L332V	332	Missense	distal	-5	no	6.961	7.432	EPSD	TCGA;ICGC;COSMIC	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	P12036	NEFH	P49841	GSK3B	S337	D340N	340	Missense	distal	3	no	6.961	6.914	EPSD	TCGA;ICGC;COSMIC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	P12036	NEFH	P49841	GSK3B	S503	G497R	497	Missense	distal	-6	no	9.470	9.397	PhosphoSitePlus	TCGA;ICGC;COSMIC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	P12036	NEFH	P49841	GSK3B	S503	G497E	497	Missense	distal	-6	no	9.470	9.392	PhosphoSitePlus	TCGA;ICGC;COSMIC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	P12036	NEFH	P49841	GSK3B	S503	G496R	496	Missense	distal	-7	no	9.470	9.490	PhosphoSitePlus	TCGA;ICGC;COSMIC	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	P12036	NEFH	P49841	GSK3B	S511	E513D	513	Missense	proximal	2	no	6.010	6.189	EPSD	TCGA;ICGC;COSMIC	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	P12036	NEFH	P49841	GSK3B	S511	A516S	516	Missense	distal	5	no	6.010	6.085	EPSD	TCGA;COSMIC	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	P12036	NEFH	P49841	GSK3B	S518	E513D	513	Missense	distal	-5	no	7.766	7.607	EPSD	TCGA;ICGC;COSMIC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	P12036	NEFH	P49841	GSK3B	S518	A516S	516	Missense	proximal	-2	no	7.766	8.100	EPSD	TCGA;COSMIC	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	P12036	NEFH	P49841	GSK3B	S518	E523K	523	Missense	distal	5	no	7.766	6.899	EPSD	TCGA;ICGC;COSMIC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	P12036	NEFH	P49841	GSK3B	S552	P553S	553	Missense	proximal	1	no	7.707	3.862	EPSD	TCGA;ICGC;COSMIC	6.007	Loss
CMGC_GSK_GSK3B_ST	P12036	NEFH	P49841	GSK3B	S552	E556K	556	Missense	distal	4	no	7.707	6.525	EPSD	TCGA;ICGC;COSMIC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	P12036	NEFH	P49841	GSK3B	S560	A564T	564	Missense	distal	4	no	5.735	7.278	EPSD	TCGA;ICGC;COSMIC	6.007	Gain
CMGC_GSK_GSK3B_ST	P12036	NEFH	P49841	GSK3B	S566	E563D	563	Missense	distal	-3	no	8.311	8.344	EPSD	TCGA;ICGC;COSMIC	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	P12036	NEFH	P49841	GSK3B	S566	E570K	570	Missense	distal	4	no	8.311	7.129	EPSD	TCGA;ICGC;COSMIC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	P12036	NEFH	P49841	GSK3B	S566	A564P	564	Missense	proximal	-2	no	8.311	8.902	EPSD	TCGA;ICGC;COSMIC	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	P12036	NEFH	P49841	GSK3B	S566	P562T	562	Missense	distal	-4	no	8.311	8.539	EPSD	TCGA;ICGC;COSMIC	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	P12036	NEFH	P49841	GSK3B	S566	A564T	564	Missense	proximal	-2	no	8.311	8.673	EPSD	TCGA;ICGC;COSMIC	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	P12036	NEFH	P49841	GSK3B	S566	E571D	571	Missense	distal	5	no	8.311	8.109	EPSD	TCGA;ICGC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	P12036	NEFH	P49841	GSK3B	S594	A598T	598	Missense	distal	4	no	6.174	7.716	EPSD	TCGA;COSMIC	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	P12036	NEFH	P49841	GSK3B	S600	A598T	598	Missense	proximal	-2	no	5.884	6.246	EPSD	TCGA;COSMIC	6.007	Gain
CMGC_GSK_GSK3B_ST	P12036	NEFH	P49841	GSK3B	S606	S606Y	606	Missense	central	0	yes	7.430	0.000	EPSD	TCGA;ICGC;COSMIC	6.007	Loss
CMGC_GSK_GSK3B_ST	P12036	NEFH	P49841	GSK3B	S606	K609N	609	Missense	distal	3	no	7.430	7.605	EPSD	TCGA;ICGC;COSMIC	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	P12036	NEFH	P49841	GSK3B	S620	P621T	621	Missense	proximal	1	no	6.904	3.713	EPSD	TCGA;ICGC;COSMIC	6.007	Loss
CMGC_GSK_GSK3B_ST	P12036	NEFH	P49841	GSK3B	S640	E644K	644	Missense	distal	4	no	7.717	6.535	EPSD	TCGA;ICGC;COSMIC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	P12036	NEFH	P49841	GSK3B	S688	K695M	695	Missense	distal	7	no	6.665	7.103	EPSD	TCGA;ICGC;COSMIC	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	P12036	NEFH	P49841	GSK3B	S688	A694T	694	Missense	distal	6	no	6.665	6.669	EPSD	TCGA;ICGC;COSMIC	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	P12036	NEFH	P49841	GSK3B	S696	A694T	694	Missense	proximal	-2	no	5.831	6.193	EPSD	TCGA;ICGC;COSMIC	6.007	Gain
CMGC_GSK_GSK3B_ST	P12036	NEFH	P49841	GSK3B	S702	K695M	695	Missense	distal	-7	no	7.076	7.075	EPSD	TCGA;ICGC;COSMIC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	P12036	NEFH	P49841	GSK3B	S730	E734K	734	Missense	distal	4	no	7.365	6.183	EPSD	TCGA;ICGC;COSMIC;GDSC;CCLE	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	P12036	NEFH	P49841	GSK3B	S744	A750T	750	Missense	distal	6	no	7.026	7.030	EPSD	TCGA;ICGC	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	P12036	NEFH	P49841	GSK3B	S744	K751N	751	Missense	distal	7	no	7.026	7.218	EPSD	TCGA;ICGC;COSMIC	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	P12036	NEFH	P49841	GSK3B	S752	A750T	750	Missense	proximal	-2	no	5.781	6.143	EPSD	TCGA;ICGC	6.007	Gain
CMGC_GSK_GSK3B_ST	P12036	NEFH	P49841	GSK3B	S758	S752F	752	Missense	distal	-6	no	6.133	6.079	EPSD	TCGA;ICGC;COSMIC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	P12036	NEFH	P49841	GSK3B	S758	K751N	751	Missense	distal	-7	no	6.133	6.117	EPSD	TCGA;ICGC;COSMIC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	P12036	NEFH	P49841	GSK3B	S807	E811K	811	Missense	distal	4	no	7.675	6.493	EPSD	TCGA;ICGC;COSMIC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	P12036	NEFH	P49841	GSK3B	T911	E915K	915	Missense	distal	4	no	6.329	5.147	EPSD	TCGA;ICGC;COSMIC	6.007	Loss
CMGC_GSK_GSK3B_ST	O00429	DNM1L	P49841	GSK3B	S40	E43Q	43	Missense	distal	3	no	8.819	8.801	PhosphoSitePlus;EPSD	TCGA;ICGC;COSMIC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	O00429	DNM1L	P49841	GSK3B	S40	S36N	36	Missense	distal	-4	no	8.819	7.521	PhosphoSitePlus;EPSD	TCGA;ICGC;COSMIC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	O00429	DNM1L	P49841	GSK3B	S40	V41M	41	Missense	proximal	1	no	8.819	8.223	PhosphoSitePlus;EPSD	TCGA;ICGC;COSMIC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	O00429	DNM1L	P49841	GSK3B	S44	E43Q	43	Missense	proximal	-1	no	6.165	6.070	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	O00429	DNM1L	P49841	GSK3B	S44	V41M	41	Missense	distal	-3	no	6.165	5.970	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	6.007	Loss
CMGC_GSK_GSK3B_ST	O00429	DNM1L	P49841	GSK3B	T189	A183T	183	Missense	distal	-6	no	6.090	6.021	EPSD	TCGA;COSMIC;GDSC;CCLE	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	Q92908	GATA6	P49841	GSK3B	S33	P36L	36	Missense	distal	3	no	6.374	6.055	EPSD	TCGA;ICGC;COSMIC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	Q92908	GATA6	P49841	GSK3B	S37	P36L	36	Missense	proximal	-1	no	10.924	10.793	PhosphoSitePlus	TCGA;ICGC;COSMIC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	Q92908	GATA6	P49841	GSK3B	S41	P36L	36	Missense	distal	-5	no	6.029	6.295	EPSD	TCGA;ICGC;COSMIC	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	Q92908	GATA6	P49841	GSK3B	T62	A69V	69	Missense	distal	7	no	8.268	8.346	EPSD	TCGA;ICGC;COSMIC;GDSC;CCLE	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	Q92908	GATA6	P49841	GSK3B	T515	S520C	520	Missense	distal	5	no	8.408	7.168	EPSD	TCGA;ICGC;COSMIC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	Q92908	GATA6	P49841	GSK3B	T515	P516L	516	Missense	proximal	1	no	8.408	5.548	EPSD	TCGA;ICGC;COSMIC	6.007	Loss
CMGC_GSK_GSK3B_ST	Q92908	GATA6	P49841	GSK3B	S523	S520C	520	Missense	distal	-3	no	6.520	6.624	EPSD	TCGA;ICGC;COSMIC	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	Q92908	GATA6	P49841	GSK3B	S523	N529K	529	Missense	distal	6	no	6.520	6.521	EPSD	TCGA;ICGC;COSMIC;GDSC;CCLE	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	Q92908	GATA6	P49841	GSK3B	S523	N529H	529	Missense	distal	6	no	6.520	6.517	EPSD	TCGA;ICGC;COSMIC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	Q92908	GATA6	P49841	GSK3B	S523	P516L	516	Missense	distal	-7	no	6.520	6.522	EPSD	TCGA;ICGC;COSMIC	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	Q92908	GATA6	P49841	GSK3B	S531	N529K	529	Missense	proximal	-2	no	8.241	8.336	EPSD	TCGA;ICGC;COSMIC;GDSC;CCLE	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	Q92908	GATA6	P49841	GSK3B	S531	N529H	529	Missense	proximal	-2	no	8.241	8.365	EPSD	TCGA;ICGC;COSMIC	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	Q92908	GATA6	P49841	GSK3B	S531	A538T	538	Missense	distal	7	no	8.241	7.835	EPSD	TCGA;ICGC;COSMIC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	Q92908	GATA6	P49841	GSK3B	S539	G540R	540	Missense	proximal	1	no	5.250	6.124	EPSD	TCGA;ICGC;COSMIC	6.007	Gain
CMGC_GSK_GSK3B_ST	P17275	JUNB	P49841	GSK3B	S70	S67N	67	Missense	distal	-3	no	8.426	8.332	EPSD	TCGA;ICGC;COSMIC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	P17275	JUNB	P49841	GSK3B	S70	Y68H	68	Missense	proximal	-2	no	8.426	8.640	EPSD	TCGA;ICGC;COSMIC	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	P30304	CDC25A	P49841	GSK3B	S88	D87Y	87	Missense	proximal	-1	no	6.665	6.586	EPSD	TCGA;ICGC;COSMIC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	P30304	CDC25A	P49841	GSK3B	S88	P89L	89	Missense	proximal	1	no	6.665	3.805	EPSD	TCGA;ICGC;COSMIC	6.007	Loss
CMGC_GSK_GSK3B_ST	P30304	CDC25A	P49841	GSK3B	S88	P91S	91	Missense	distal	3	no	6.665	6.648	EPSD	TCGA;ICGC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	P30304	CDC25A	P49841	GSK3B	S116	R121S	121	Missense	distal	5	no	6.284	5.967	EPSD	TCGA;ICGC;COSMIC	6.007	Loss
CMGC_GSK_GSK3B_ST	P30304	CDC25A	P49841	GSK3B	S116	L119V	119	Missense	distal	3	no	6.284	6.376	EPSD	TCGA;ICGC;COSMIC	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	P30304	CDC25A	P49841	GSK3B	S116	P117S	117	Missense	proximal	1	no	6.284	2.439	EPSD	TCGA;ICGC;COSMIC	6.007	Loss
CMGC_GSK_GSK3B_ST	P30304	CDC25A	P49841	GSK3B	S116	L113F	113	Missense	distal	-3	no	6.284	6.341	EPSD	TCGA;ICGC;COSMIC	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	P30304	CDC25A	P49841	GSK3B	S263	R270P	270	Missense	distal	7	no	6.869	6.368	EPSD	TCGA;ICGC;COSMIC;GDSC;CCLE	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	P30304	CDC25A	P49841	GSK3B	S279	P284T	284	Missense	distal	5	no	6.111	5.134	EPSD	TCGA;ICGC;COSMIC	6.007	Loss
CMGC_GSK_GSK3B_ST	P30304	CDC25A	P49841	GSK3B	S279	R275K	275	Missense	distal	-4	no	6.111	6.433	EPSD	TCGA;ICGC	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	P30304	CDC25A	P49841	GSK3B	S283	P284T	284	Missense	proximal	1	no	10.746	7.555	EPSD	TCGA;ICGC;COSMIC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	P30304	CDC25A	P49841	GSK3B	S298	S298N	298	Missense	central	0	yes	8.655	0.000	EPSD	TCGA;ICGC;COSMIC	6.007	Loss
CMGC_GSK_GSK3B_ST	P30304	CDC25A	P49841	GSK3B	S317	E310K	310	Missense	distal	-7	no	7.549	7.538	EPSD	TCGA;ICGC;COSMIC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	P30304	CDC25A	P49841	GSK3B	S317	T311A	311	Missense	distal	-6	no	7.549	7.617	EPSD	TCGA;ICGC;COSMIC	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	P30304	CDC25A	P49841	GSK3B	S317	S317F	317	Missense	central	0	yes	7.549	0.000	EPSD	TCGA;ICGC;COSMIC	6.007	Loss
CMGC_GSK_GSK3B_ST	P30304	CDC25A	P49841	GSK3B	S321	S317F	317	Missense	distal	-4	no	7.617	6.463	EPSD	TCGA;ICGC;COSMIC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	P30304	CDC25A	P49841	GSK3B	S361	A366T	366	Missense	distal	5	no	5.991	6.044	EPSD	TCGA;ICGC;COSMIC	6.007	Gain
CMGC_GSK_GSK3B_ST	P30304	CDC25A	P49841	GSK3B	S361	Q355P	355	Missense	distal	-6	no	5.991	6.017	EPSD	TCGA;ICGC;COSMIC	6.007	Gain
CMGC_GSK_GSK3B_ST	P30304	CDC25A	P49841	GSK3B	S505	S505N	505	Missense	central	0	yes	6.134	0.000	EPSD	TCGA;ICGC;COSMIC	6.007	Loss
CMGC_GSK_GSK3B_ST	Q9NRR4	DROSHA	P49841	GSK3B	S217	P222L	222	Missense	distal	5	no	6.119	4.838	EPSD	TCGA;ICGC;COSMIC	6.007	Loss
CMGC_GSK_GSK3B_ST	Q9NRR4	DROSHA	P49841	GSK3B	S217	P213L	213	Missense	distal	-4	no	6.119	5.332	EPSD	TCGA;ICGC;COSMIC	6.007	Loss
CMGC_GSK_GSK3B_ST	Q9NRR4	DROSHA	P49841	GSK3B	S217	P213S	213	Missense	distal	-4	no	6.119	6.682	EPSD	TCGA;ICGC;COSMIC	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	Q9NRR4	DROSHA	P49841	GSK3B	S217	P222A	222	Missense	distal	5	no	6.119	5.090	EPSD	TCGA;ICGC;COSMIC	6.007	Loss
CMGC_GSK_GSK3B_ST	Q9NRR4	DROSHA	P49841	GSK3B	S221	P222L	222	Missense	proximal	1	no	7.086	4.226	EPSD	TCGA;ICGC;COSMIC	6.007	Loss
CMGC_GSK_GSK3B_ST	Q9NRR4	DROSHA	P49841	GSK3B	S221	P222A	222	Missense	proximal	1	no	7.086	3.354	EPSD	TCGA;ICGC;COSMIC	6.007	Loss
CMGC_GSK_GSK3B_ST	Q9NRR4	DROSHA	P49841	GSK3B	T274	R273I	273	Missense	proximal	-1	no	8.231	8.218	EPSD	TCGA	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	Q9NRR4	DROSHA	P49841	GSK3B	T274	D270Y	270	Missense	distal	-4	no	8.231	8.031	EPSD	TCGA;ICGC;COSMIC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	Q9NRR4	DROSHA	P49841	GSK3B	T274	D268V	268	Missense	distal	-6	no	8.231	8.189	EPSD	TCGA;ICGC;COSMIC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	Q9NRR4	DROSHA	P49841	GSK3B	T274	S280C	280	Missense	distal	6	no	8.231	8.217	EPSD	TCGA;ICGC;COSMIC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	Q9NRR4	DROSHA	P49841	GSK3B	S276	R273I	273	Missense	distal	-3	no	8.553	8.497	EPSD	TCGA	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	Q9NRR4	DROSHA	P49841	GSK3B	S276	D270Y	270	Missense	distal	-6	no	8.553	8.491	EPSD	TCGA;ICGC;COSMIC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	Q9NRR4	DROSHA	P49841	GSK3B	S276	S280C	280	Missense	distal	4	no	8.553	2.420	EPSD	TCGA;ICGC;COSMIC	6.007	Loss
CMGC_GSK_GSK3B_ST	Q9NRR4	DROSHA	P49841	GSK3B	S284	E282K	282	Missense	proximal	-2	no	6.751	6.720	EPSD	TCGA;ICGC;COSMIC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	Q9NRR4	DROSHA	P49841	GSK3B	S284	E286D	286	Missense	proximal	2	no	6.751	6.931	EPSD	TCGA;ICGC	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	Q9NRR4	DROSHA	P49841	GSK3B	S284	R285I	285	Missense	proximal	1	no	6.751	5.190	EPSD	TCGA;ICGC;COSMIC	6.007	Loss
CMGC_GSK_GSK3B_ST	Q9NRR4	DROSHA	P49841	GSK3B	S284	S280C	280	Missense	distal	-4	no	6.751	4.637	EPSD	TCGA;ICGC;COSMIC	6.007	Loss
CMGC_GSK_GSK3B_ST	Q9NRR4	DROSHA	P49841	GSK3B	S284	R287L	287	Missense	distal	3	no	6.751	6.822	EPSD	TCGA;ICGC;COSMIC	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	Q9NRR4	DROSHA	P49841	GSK3B	S300	R305T	305	Missense	distal	5	no	9.866	9.527	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	Q9NRR4	DROSHA	P49841	GSK3B	S300	E304A	304	Missense	distal	4	no	9.866	9.475	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	Q9NRR4	DROSHA	P49841	GSK3B	T330	G335E	335	Missense	distal	5	no	6.832	7.098	EPSD	TCGA;ICGC	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	Q9NRR4	DROSHA	P49841	GSK3B	S343	S343Y	343	Missense	central	0	yes	6.425	0.000	EPSD	TCGA;ICGC;COSMIC	6.007	Loss
CMGC_GSK_GSK3B_ST	Q9NRR4	DROSHA	P49841	GSK3B	S355	R354C	354	Missense	proximal	-1	no	6.501	6.602	EPSD	TCGA;ICGC;COSMIC	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	Q9NRR4	DROSHA	P49841	GSK3B	S491	E484K	484	Missense	distal	-7	no	7.852	7.841	EPSD	TCGA;ICGC;COSMIC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	Q9NRR4	DROSHA	P49841	GSK3B	T747	T747M	747	Missense	central	0	yes	6.272	0.000	EPSD	TCGA;COSMIC	6.007	Loss
CMGC_GSK_GSK3B_ST	Q9NRR4	DROSHA	P49841	GSK3B	T747	M740V	740	Missense	distal	-7	no	6.272	6.273	EPSD	TCGA;COSMIC	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	Q9NRR4	DROSHA	P49841	GSK3B	T958	S960W	960	Missense	proximal	2	no	6.513	6.101	EPSD	TCGA;ICGC;COSMIC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	Q9NRR4	DROSHA	P49841	GSK3B	T958	N963S	963	Missense	distal	5	no	6.513	6.833	EPSD	TCGA;COSMIC	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	Q9NRR4	DROSHA	P49841	GSK3B	T958	S960L	960	Missense	proximal	2	no	6.513	6.572	EPSD	TCGA;ICGC;COSMIC;GDSC;CCLE	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	Q9NRR4	DROSHA	P49841	GSK3B	T958	D955Y	955	Missense	distal	-3	no	6.513	6.607	EPSD	TCGA;ICGC;COSMIC	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	Q9NRR4	DROSHA	P49841	GSK3B	S1293	R1296Q	1296	Missense	distal	3	no	5.829	6.162	EPSD	TCGA;ICGC;COSMIC	6.007	Gain
CMGC_GSK_GSK3B_ST	P15924	DSP	P49841	GSK3B	T59	M62L	62	Missense	distal	3	no	7.837	7.727	EPSD	TCGA;ICGC;COSMIC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	P15924	DSP	P49841	GSK3B	T59	Q66H	66	Missense	distal	7	no	7.837	8.373	EPSD	TCGA;ICGC	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	P15924	DSP	P49841	GSK3B	S157	I156M	156	Missense	proximal	-1	no	6.169	6.269	EPSD	TCGA;ICGC;COSMIC	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	P15924	DSP	P49841	GSK3B	S157	R160G	160	Missense	distal	3	no	6.169	6.584	EPSD	TCGA;ICGC;COSMIC	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	P15924	DSP	P49841	GSK3B	S157	R150Q	150	Missense	distal	-7	no	6.169	6.166	EPSD	TCGA;ICGC;COSMIC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	P15924	DSP	P49841	GSK3B	S157	I156T	156	Missense	proximal	-1	no	6.169	6.244	EPSD	TCGA;ICGC;COSMIC	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	P15924	DSP	P49841	GSK3B	T634	E639K	639	Missense	distal	5	no	6.647	5.780	EPSD	TCGA;ICGC;COSMIC	6.007	Loss
CMGC_GSK_GSK3B_ST	P15924	DSP	P49841	GSK3B	T1436	Q1432P	1432	Missense	distal	-4	no	5.795	6.061	EPSD	TCGA;ICGC;COSMIC	6.007	Gain
CMGC_GSK_GSK3B_ST	P15924	DSP	P49841	GSK3B	S2024	S2022C	2022	Missense	proximal	-2	no	7.352	7.041	EPSD	TCGA;ICGC;COSMIC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	P15924	DSP	P49841	GSK3B	S2024	S2017F	2017	Missense	distal	-7	no	7.352	7.362	EPSD	TCGA;ICGC;COSMIC	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	P15924	DSP	P49841	GSK3B	S2024	I2018V	2018	Missense	distal	-6	no	7.352	7.348	EPSD	TCGA;ICGC;COSMIC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	P15924	DSP	P49841	GSK3B	S2024	G2020E	2020	Missense	distal	-4	no	7.352	7.183	EPSD	TCGA;ICGC;COSMIC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	P15924	DSP	P49841	GSK3B	S2024	E2027K	2027	Missense	distal	3	no	7.352	7.245	EPSD	TCGA;ICGC;COSMIC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	P15924	DSP	P49841	GSK3B	S2024	G2020R	2020	Missense	distal	-4	no	7.352	6.593	EPSD	TCGA;ICGC;COSMIC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	P15924	DSP	P49841	GSK3B	S2024	S2030Y	2030	Missense	distal	6	no	7.352	7.346	EPSD	TCGA;ICGC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	P15924	DSP	P49841	GSK3B	S2041	I2040V	2040	Missense	proximal	-1	no	8.396	8.594	EPSD	TCGA;ICGC;COSMIC	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	P15924	DSP	P49841	GSK3B	S2041	K2038E	2038	Missense	distal	-3	no	8.396	8.385	EPSD	TCGA;ICGC;COSMIC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	P15924	DSP	P49841	GSK3B	S2041	V2046I	2046	Missense	distal	5	no	8.396	8.230	EPSD	TCGA;ICGC;COSMIC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	P15924	DSP	P49841	GSK3B	S2549	Q2556L	2556	Missense	distal	7	no	6.507	6.403	EPSD	TCGA;ICGC;COSMIC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	P15924	DSP	P49841	GSK3B	S2549	G2550V	2550	Missense	proximal	1	no	6.507	6.711	EPSD	TCGA;ICGC;COSMIC	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	P15924	DSP	P49841	GSK3B	S2549	F2543L	2543	Missense	distal	-6	no	6.507	6.560	EPSD	TCGA;ICGC	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	P15924	DSP	P49841	GSK3B	S2551	Q2556L	2556	Missense	distal	5	no	6.406	6.102	EPSD	TCGA;ICGC;COSMIC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	P15924	DSP	P49841	GSK3B	S2551	G2550V	2550	Missense	proximal	-1	no	6.406	6.447	EPSD	TCGA;ICGC;COSMIC	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	P15924	DSP	P49841	GSK3B	S2585	K2592N	2592	Missense	distal	7	no	5.865	6.057	EPSD	TCGA;ICGC;COSMIC	6.007	Gain
CMGC_GSK_GSK3B_ST	P15924	DSP	P49841	GSK3B	S2594	K2592N	2592	Missense	proximal	-2	no	6.223	6.129	EPSD	TCGA;ICGC;COSMIC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	P15924	DSP	P49841	GSK3B	S2594	S2597F	2597	Missense	distal	3	no	6.223	6.013	EPSD	TCGA;ICGC;COSMIC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	P15924	DSP	P49841	GSK3B	S2594	V2599I	2599	Missense	distal	5	no	6.223	6.058	EPSD	TCGA;ICGC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	P15924	DSP	P49841	GSK3B	S2594	N2601T	2601	Missense	distal	7	no	6.223	6.042	EPSD	TCGA;ICGC;COSMIC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	P15924	DSP	P49841	GSK3B	S2598	K2592N	2592	Missense	distal	-6	no	6.965	7.025	EPSD	TCGA;ICGC;COSMIC	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	P15924	DSP	P49841	GSK3B	S2598	S2597F	2597	Missense	proximal	-1	no	6.965	6.834	EPSD	TCGA;ICGC;COSMIC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	P15924	DSP	P49841	GSK3B	S2598	L2602V	2602	Missense	distal	4	no	6.965	7.293	EPSD	TCGA;ICGC;COSMIC	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	P15924	DSP	P49841	GSK3B	S2598	V2599I	2599	Missense	proximal	1	no	6.965	6.074	EPSD	TCGA;ICGC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	P15924	DSP	P49841	GSK3B	S2598	N2601T	2601	Missense	distal	3	no	6.965	6.884	EPSD	TCGA;ICGC;COSMIC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	P15924	DSP	P49841	GSK3B	T2612	S2608C	2608	Missense	distal	-4	no	7.690	5.576	EPSD	TCGA;ICGC;COSMIC	6.007	Loss
CMGC_GSK_GSK3B_ST	P15924	DSP	P49841	GSK3B	T2612	E2614K	2614	Missense	proximal	2	no	7.690	7.730	EPSD	TCGA;ICGC;COSMIC	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	P15924	DSP	P49841	GSK3B	S2617	E2614K	2614	Missense	distal	-3	no	6.490	6.501	EPSD	TCGA;ICGC;COSMIC	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	P15924	DSP	P49841	GSK3B	S2617	D2624N	2624	Missense	distal	7	no	6.490	6.559	EPSD	TCGA;ICGC;COSMIC	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	P15924	DSP	P49841	GSK3B	S2670	A2674T	2674	Missense	distal	4	no	4.703	6.246	EPSD	TCGA;ICGC;COSMIC	6.007	Gain
CMGC_GSK_GSK3B_ST	P15924	DSP	P49841	GSK3B	S2815	S2809P	2809	Missense	distal	-6	no	9.199	9.220	EPSD	TCGA;ICGC	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	P15924	DSP	P49841	GSK3B	S2815	S2821L	2821	Missense	distal	6	no	9.199	9.194	EPSD	TCGA;ICGC;COSMIC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	P15924	DSP	P49841	GSK3B	S2821	P2823Q	2823	Missense	proximal	2	no	7.158	6.937	EPSD	TCGA;ICGC;COSMIC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	P15924	DSP	P49841	GSK3B	S2821	R2826H	2826	Missense	distal	5	no	7.158	6.169	EPSD	TCGA;ICGC;COSMIC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	P15924	DSP	P49841	GSK3B	S2821	S2821L	2821	Missense	central	0	yes	7.158	0.000	EPSD	TCGA;ICGC;COSMIC	6.007	Loss
CMGC_GSK_GSK3B_ST	P15924	DSP	P49841	GSK3B	S2825	P2823Q	2823	Missense	proximal	-2	no	9.505	9.204	EPSD	TCGA;ICGC;COSMIC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	P15924	DSP	P49841	GSK3B	S2825	R2826H	2826	Missense	proximal	1	no	9.505	8.125	EPSD	TCGA;ICGC;COSMIC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	P15924	DSP	P49841	GSK3B	S2825	S2831L	2831	Missense	distal	6	no	9.505	9.501	EPSD	TCGA;ICGC;COSMIC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	P15924	DSP	P49841	GSK3B	S2825	S2821L	2821	Missense	distal	-4	no	9.505	8.155	EPSD	TCGA;ICGC;COSMIC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	P15924	DSP	P49841	GSK3B	S2825	R2830H	2830	Missense	distal	5	no	9.505	8.516	EPSD	TCGA;ICGC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	P15924	DSP	P49841	GSK3B	S2827	P2823Q	2823	Missense	distal	-4	no	7.990	7.724	EPSD	TCGA;ICGC;COSMIC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	P15924	DSP	P49841	GSK3B	S2827	R2826H	2826	Missense	proximal	-1	no	7.990	8.076	EPSD	TCGA;ICGC;COSMIC	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	P15924	DSP	P49841	GSK3B	S2827	S2833Y	2833	Missense	distal	6	no	7.990	7.984	EPSD	TCGA;ICGC;COSMIC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	P15924	DSP	P49841	GSK3B	S2827	S2831L	2831	Missense	distal	4	no	7.990	5.273	EPSD	TCGA;ICGC;COSMIC	6.007	Loss
CMGC_GSK_GSK3B_ST	P15924	DSP	P49841	GSK3B	S2827	S2821L	2821	Missense	distal	-6	no	7.990	7.989	EPSD	TCGA;ICGC;COSMIC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	P15924	DSP	P49841	GSK3B	S2827	R2830H	2830	Missense	distal	3	no	7.990	8.333	EPSD	TCGA;ICGC	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	P15924	DSP	P49841	GSK3B	S2829	P2823Q	2823	Missense	distal	-6	no	10.627	10.602	EPSD	TCGA;ICGC;COSMIC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	P15924	DSP	P49841	GSK3B	S2829	R2826H	2826	Missense	distal	-3	no	10.627	10.570	EPSD	TCGA;ICGC;COSMIC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	P15924	DSP	P49841	GSK3B	S2829	S2833Y	2833	Missense	distal	4	no	10.627	7.114	EPSD	TCGA;ICGC;COSMIC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	P15924	DSP	P49841	GSK3B	S2829	S2831L	2831	Missense	proximal	2	no	10.627	10.687	EPSD	TCGA;ICGC;COSMIC	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	P15924	DSP	P49841	GSK3B	S2829	R2830H	2830	Missense	proximal	1	no	10.627	9.247	EPSD	TCGA;ICGC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	P15924	DSP	P49841	GSK3B	S2831	R2826H	2826	Missense	distal	-5	no	7.617	7.086	EPSD	TCGA;ICGC;COSMIC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	P15924	DSP	P49841	GSK3B	S2831	S2833Y	2833	Missense	proximal	2	no	7.617	7.384	EPSD	TCGA;ICGC;COSMIC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	P15924	DSP	P49841	GSK3B	S2831	R2838C	2838	Missense	distal	7	no	7.617	7.571	EPSD	TCGA;ICGC;COSMIC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	P15924	DSP	P49841	GSK3B	S2831	S2831L	2831	Missense	central	0	yes	7.617	0.000	EPSD	TCGA;ICGC;COSMIC	6.007	Loss
CMGC_GSK_GSK3B_ST	P15924	DSP	P49841	GSK3B	S2831	R2830H	2830	Missense	proximal	-1	no	7.617	7.702	EPSD	TCGA;ICGC	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	P15924	DSP	P49841	GSK3B	S2833	S2833Y	2833	Missense	central	0	yes	9.890	0.000	EPSD	TCGA;ICGC;COSMIC	6.007	Loss
CMGC_GSK_GSK3B_ST	P15924	DSP	P49841	GSK3B	S2833	R2838C	2838	Missense	distal	5	no	9.890	8.334	EPSD	TCGA;ICGC;COSMIC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	P15924	DSP	P49841	GSK3B	S2833	S2831L	2831	Missense	proximal	-2	no	9.890	9.816	EPSD	TCGA;ICGC;COSMIC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	P15924	DSP	P49841	GSK3B	S2833	R2830H	2830	Missense	distal	-3	no	9.890	9.833	EPSD	TCGA;ICGC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	P15924	DSP	P49841	GSK3B	S2835	S2833Y	2833	Missense	proximal	-2	no	8.493	8.173	EPSD	TCGA;ICGC;COSMIC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	P15924	DSP	P49841	GSK3B	S2835	R2842H	2842	Missense	distal	7	no	8.493	8.681	EPSD	TCGA;ICGC;GDSC;CCLE	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	P15924	DSP	P49841	GSK3B	S2835	R2838C	2838	Missense	distal	3	no	8.493	8.648	EPSD	TCGA;ICGC;COSMIC	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	P15924	DSP	P49841	GSK3B	S2835	S2831L	2831	Missense	distal	-4	no	8.493	7.142	EPSD	TCGA;ICGC;COSMIC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	P15924	DSP	P49841	GSK3B	S2835	R2830H	2830	Missense	distal	-5	no	8.493	7.962	EPSD	TCGA;ICGC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	P15924	DSP	P49841	GSK3B	S2837	S2833Y	2833	Missense	distal	-4	no	9.051	8.250	EPSD	TCGA;ICGC;COSMIC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	P15924	DSP	P49841	GSK3B	S2837	R2842H	2842	Missense	distal	5	no	9.051	8.062	EPSD	TCGA;ICGC;GDSC;CCLE	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	P15924	DSP	P49841	GSK3B	S2837	R2838C	2838	Missense	proximal	1	no	9.051	7.048	EPSD	TCGA;ICGC;COSMIC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	P15924	DSP	P49841	GSK3B	S2837	S2831L	2831	Missense	distal	-6	no	9.051	9.050	EPSD	TCGA;ICGC;COSMIC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	P15924	DSP	P49841	GSK3B	S2837	G2844E	2844	Missense	distal	7	no	9.051	9.070	EPSD	TCGA;ICGC	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	P15924	DSP	P49841	GSK3B	S2839	S2833Y	2833	Missense	distal	-6	no	7.703	7.617	EPSD	TCGA;ICGC;COSMIC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	P15924	DSP	P49841	GSK3B	S2839	R2842H	2842	Missense	distal	3	no	7.703	8.045	EPSD	TCGA;ICGC;GDSC;CCLE	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	P15924	DSP	P49841	GSK3B	S2839	R2838C	2838	Missense	proximal	-1	no	7.703	7.804	EPSD	TCGA;ICGC;COSMIC	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	P15924	DSP	P49841	GSK3B	S2839	G2844E	2844	Missense	distal	5	no	7.703	7.969	EPSD	TCGA;ICGC	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	P15924	DSP	P49841	GSK3B	S2839	R2846Q	2846	Missense	distal	7	no	7.703	7.355	EPSD	TCGA;ICGC;COSMIC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	P15924	DSP	P49841	GSK3B	S2841	R2842H	2842	Missense	proximal	1	no	9.923	8.542	EPSD	TCGA;ICGC;GDSC;CCLE	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	P15924	DSP	P49841	GSK3B	S2841	R2838C	2838	Missense	distal	-3	no	9.923	9.858	EPSD	TCGA;ICGC;COSMIC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	P15924	DSP	P49841	GSK3B	S2841	G2844E	2844	Missense	distal	3	no	9.923	9.860	EPSD	TCGA;ICGC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	P15924	DSP	P49841	GSK3B	S2841	R2846Q	2846	Missense	distal	5	no	9.923	9.584	EPSD	TCGA;ICGC;COSMIC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	P15924	DSP	P49841	GSK3B	S2845	R2842H	2842	Missense	distal	-3	no	9.477	9.420	PhosphoSitePlus;EPSD	TCGA;ICGC;GDSC;CCLE	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	P15924	DSP	P49841	GSK3B	S2845	R2838C	2838	Missense	distal	-7	no	9.477	9.481	PhosphoSitePlus;EPSD	TCGA;ICGC;COSMIC	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	P15924	DSP	P49841	GSK3B	S2845	A2852T	2852	Missense	distal	7	no	9.477	9.070	PhosphoSitePlus;EPSD	TCGA;ICGC;COSMIC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	P15924	DSP	P49841	GSK3B	S2845	G2844E	2844	Missense	proximal	-1	no	9.477	9.458	PhosphoSitePlus;EPSD	TCGA;ICGC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	P15924	DSP	P49841	GSK3B	S2845	R2846Q	2846	Missense	proximal	1	no	9.477	8.528	PhosphoSitePlus;EPSD	TCGA;ICGC;COSMIC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	P15924	DSP	P49841	GSK3B	S2849	S2856C	2856	Missense	distal	7	no	6.665	7.057	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	P15924	DSP	P49841	GSK3B	S2849	A2852T	2852	Missense	distal	3	no	6.665	6.969	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	P15924	DSP	P49841	GSK3B	S2849	G2844E	2844	Missense	distal	-5	no	6.665	6.630	EPSD;PhosphoSitePlus	TCGA;ICGC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	P15924	DSP	P49841	GSK3B	S2849	R2846Q	2846	Missense	distal	-3	no	6.665	6.526	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	P15924	DSP	P49841	GSK3B	T2853	S2859C	2859	Missense	distal	6	no	6.657	6.644	EPSD	TCGA;ICGC;COSMIC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	P15924	DSP	P49841	GSK3B	T2853	S2856C	2856	Missense	distal	3	no	6.657	6.441	EPSD	TCGA;ICGC;COSMIC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	P15924	DSP	P49841	GSK3B	T2853	A2852T	2852	Missense	proximal	-1	no	6.657	6.736	EPSD	TCGA;ICGC;COSMIC	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	P15924	DSP	P49841	GSK3B	T2853	R2846Q	2846	Missense	distal	-7	no	6.657	6.654	EPSD	TCGA;ICGC;COSMIC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	P15924	DSP	P49841	GSK3B	S2857	S2861Y	2861	Missense	distal	4	no	7.059	3.546	EPSD	TCGA;ICGC;COSMIC	6.007	Loss
CMGC_GSK_GSK3B_ST	P15924	DSP	P49841	GSK3B	S2857	S2859C	2859	Missense	proximal	2	no	7.059	6.567	EPSD	TCGA;ICGC;COSMIC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	P15924	DSP	P49841	GSK3B	S2857	S2861F	2861	Missense	distal	4	no	7.059	3.445	EPSD	TCGA;ICGC;COSMIC	6.007	Loss
CMGC_GSK_GSK3B_ST	P15924	DSP	P49841	GSK3B	S2857	S2856C	2856	Missense	proximal	-1	no	7.059	7.023	EPSD	TCGA;ICGC;COSMIC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	P15924	DSP	P49841	GSK3B	S2857	A2852T	2852	Missense	distal	-5	no	7.059	7.071	EPSD	TCGA;ICGC;COSMIC	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	P15924	DSP	P49841	GSK3B	S2857	S2863P	2863	Missense	distal	6	no	7.059	7.061	EPSD	TCGA;ICGC;COSMIC	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	P15924	DSP	P49841	GSK3B	S2861	S2861Y	2861	Missense	central	0	yes	8.185	0.000	EPSD	TCGA;ICGC;COSMIC	6.007	Loss
CMGC_GSK_GSK3B_ST	P15924	DSP	P49841	GSK3B	S2861	S2859C	2859	Missense	proximal	-2	no	8.185	7.873	EPSD	TCGA;ICGC;COSMIC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	P15924	DSP	P49841	GSK3B	S2861	S2861F	2861	Missense	central	0	yes	8.185	0.000	EPSD	TCGA;ICGC;COSMIC	6.007	Loss
CMGC_GSK_GSK3B_ST	P15924	DSP	P49841	GSK3B	S2861	S2856C	2856	Missense	distal	-5	no	8.185	8.704	EPSD	TCGA;ICGC;COSMIC	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	P15924	DSP	P49841	GSK3B	S2861	S2863P	2863	Missense	proximal	2	no	8.185	8.629	EPSD	TCGA;ICGC;COSMIC	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	P15924	DSP	P49841	GSK3B	S2863	S2861Y	2861	Missense	proximal	-2	no	7.467	7.148	EPSD	TCGA;ICGC;COSMIC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	P15924	DSP	P49841	GSK3B	S2863	S2859C	2859	Missense	distal	-4	no	7.467	5.353	EPSD	TCGA;ICGC;COSMIC	6.007	Loss
CMGC_GSK_GSK3B_ST	P15924	DSP	P49841	GSK3B	S2863	S2861F	2861	Missense	proximal	-2	no	7.467	7.137	EPSD	TCGA;ICGC;COSMIC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	P15924	DSP	P49841	GSK3B	S2863	S2856C	2856	Missense	distal	-7	no	7.467	7.490	EPSD	TCGA;ICGC;COSMIC	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	P15924	DSP	P49841	GSK3B	S2863	S2863P	2863	Missense	central	0	yes	7.467	0.000	EPSD	TCGA;ICGC;COSMIC	6.007	Loss
CMGC_GSK_GSK3B_ST	P60484	PTEN	P49841	GSK3B	T366	E373K	373	Missense	distal	7	no	10.540	10.431	PhosphoSitePlus;EPSD	TCGA;ICGC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	P60484	PTEN	P49841	GSK3B	T366	N372D	372	Missense	distal	6	no	10.540	10.539	PhosphoSitePlus;EPSD	TCGA;ICGC;COSMIC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	Q07812	BAX	P49841	GSK3B	S87	R89Q	89	Missense	proximal	2	no	7.032	7.237	EPSD	TCGA;ICGC;COSMIC	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	Q07812	BAX	P49841	GSK3B	S87	A82T	82	Missense	distal	-5	no	7.032	7.044	EPSD	TCGA;COSMIC	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	Q07812	BAX	P49841	GSK3B	S87	A82S	82	Missense	distal	-5	no	7.032	6.755	EPSD	TCGA;ICGC;COSMIC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	Q07812	BAX	P49841	GSK3B	S87	R94Q	94	Missense	distal	7	no	7.032	6.685	EPSD	TCGA;ICGC;COSMIC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	Q07812	BAX	P49841	GSK3B	S87	P88S	88	Missense	proximal	1	no	7.032	3.188	EPSD	TCGA;ICGC;COSMIC;GDSC;CCLE	6.007	Loss
CMGC_GSK_GSK3B_ST	Q07812	BAX	P49841	GSK3B	S87	P88L	88	Missense	proximal	1	no	7.032	4.172	EPSD	TCGA;ICGC;COSMIC	6.007	Loss
CMGC_GSK_GSK3B_ST	P33076	CIITA	P49841	GSK3B	S280	R283Q	283	Missense	distal	3	no	6.911	7.244	EPSD	TCGA;COSMIC	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	P33076	CIITA	P49841	GSK3B	S280	P281A	281	Missense	proximal	1	no	6.911	3.179	EPSD	TCGA;COSMIC	6.007	Loss
CMGC_GSK_GSK3B_ST	P33076	CIITA	P49841	GSK3B	S280	T273I	273	Missense	distal	-7	no	6.911	6.912	EPSD	TCGA;COSMIC	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	P33076	CIITA	P49841	GSK3B	S373	R380W	380	Missense	distal	7	no	6.191	6.300	PhosphoSitePlus	TCGA;ICGC;COSMIC	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	P33076	CIITA	P49841	GSK3B	S373	L378P	378	Missense	distal	5	no	6.191	7.472	PhosphoSitePlus	TCGA;ICGC;COSMIC	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	P33076	CIITA	P49841	GSK3B	S834	T841M	841	Missense	distal	7	no	6.984	7.411	EPSD	TCGA	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	P33076	CIITA	P49841	GSK3B	S834	R832H	832	Missense	proximal	-2	no	6.984	6.994	EPSD	TCGA;ICGC	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	P33076	CIITA	P49841	GSK3B	S943	S944W	944	Missense	proximal	1	no	5.113	6.855	EPSD	TCGA;COSMIC	6.007	Gain
CMGC_GSK_GSK3B_ST	P33076	CIITA	P49841	GSK3B	S944	T940M	940	Missense	distal	-4	no	6.146	5.421	EPSD	TCGA;COSMIC	6.007	Loss
CMGC_GSK_GSK3B_ST	P33076	CIITA	P49841	GSK3B	S944	S944W	944	Missense	central	0	yes	6.146	0.000	EPSD	TCGA;COSMIC	6.007	Loss
CMGC_GSK_GSK3B_ST	P33076	CIITA	P49841	GSK3B	S944	S942R	942	Missense	proximal	-2	no	6.146	6.030	EPSD	TCGA	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	Q14103	HNRNPD	P49841	GSK3B	S190	E196Q	196	Missense	distal	6	no	6.370	6.373	EPSD	TCGA;ICGC;COSMIC	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	Q14103	HNRNPD	P49841	GSK3B	S190	K183N	183	Missense	distal	-7	no	6.370	6.355	EPSD	TCGA;ICGC;COSMIC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	Q14103	HNRNPD	P49841	GSK3B	S190	I184N	184	Missense	distal	-6	no	6.370	6.431	EPSD	TCGA;ICGC;COSMIC	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	P23246	SFPQ	P49841	GSK3B	S379	N384S	384	Missense	distal	5	no	8.533	8.853	EPSD	TCGA;ICGC;COSMIC	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	P23246	SFPQ	P49841	GSK3B	T476	R479C	479	Missense	distal	3	no	6.076	6.231	EPSD	TCGA;ICGC;COSMIC;CCLE	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	P23246	SFPQ	P49841	GSK3B	T476	A481T	481	Missense	distal	5	no	6.076	6.128	EPSD	TCGA;ICGC	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	P23246	SFPQ	P49841	GSK3B	T687	R693I	693	Missense	distal	6	no	7.106	7.110	PhosphoSitePlus	TCGA;ICGC;COSMIC	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	P23246	SFPQ	P49841	GSK3B	T687	G690E	690	Missense	distal	3	no	7.106	7.043	PhosphoSitePlus	TCGA;ICGC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	Q96KS0	EGLN2	P49841	GSK3B	S70	R77Q	77	Missense	distal	7	no	8.517	8.169	EPSD	TCGA;ICGC;COSMIC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	Q96KS0	EGLN2	P49841	GSK3B	S70	R77W	77	Missense	distal	7	no	8.517	8.626	EPSD	TCGA;ICGC;COSMIC	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	Q96KS0	EGLN2	P49841	GSK3B	S70	A68T	68	Missense	proximal	-2	no	8.517	8.879	EPSD	TCGA;ICGC	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	Q96KS0	EGLN2	P49841	GSK3B	S74	R77Q	77	Missense	distal	3	no	8.306	8.639	EPSD	TCGA;ICGC;COSMIC	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	Q96KS0	EGLN2	P49841	GSK3B	S74	R77W	77	Missense	distal	3	no	8.306	8.565	EPSD	TCGA;ICGC;COSMIC	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	Q96KS0	EGLN2	P49841	GSK3B	S74	A68T	68	Missense	distal	-6	no	8.306	8.238	EPSD	TCGA;ICGC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	Q96KS0	EGLN2	P49841	GSK3B	S130	R134Q	134	Missense	distal	4	no	8.108	7.582	EPSD	TCGA;ICGC;COSMIC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	Q96KS0	EGLN2	P49841	GSK3B	S130	R134L	134	Missense	distal	4	no	8.108	8.428	EPSD	TCGA;ICGC	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	Q96KS0	EGLN2	P49841	GSK3B	S401	V400A	400	Missense	proximal	-1	no	9.225	9.022	PhosphoSitePlus;EPSD	TCGA;COSMIC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	Q9UKA4	AKAP11	P49841	GSK3B	S29	Q32H	32	Missense	distal	3	no	7.135	7.144	EPSD	TCGA;ICGC;COSMIC	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	Q9UKA4	AKAP11	P49841	GSK3B	S130	R137M	137	Missense	distal	7	no	7.951	7.882	EPSD	TCGA;ICGC;COSMIC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	Q9UKA4	AKAP11	P49841	GSK3B	T269	S263F	263	Missense	distal	-6	no	7.843	7.790	EPSD	TCGA;ICGC;COSMIC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	Q9UKA4	AKAP11	P49841	GSK3B	T269	T270P	270	Missense	proximal	1	no	7.843	11.034	EPSD	TCGA;ICGC	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	Q9UKA4	AKAP11	P49841	GSK3B	S273	T270P	270	Missense	distal	-3	no	6.050	5.909	EPSD	TCGA;ICGC	6.007	Loss
CMGC_GSK_GSK3B_ST	Q9UKA4	AKAP11	P49841	GSK3B	S483	Y485C	485	Missense	proximal	2	no	6.479	6.218	EPSD	TCGA;ICGC;COSMIC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	Q9UKA4	AKAP11	P49841	GSK3B	S483	H481Y	481	Missense	proximal	-2	no	6.479	6.265	EPSD	TCGA;ICGC;COSMIC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	Q9UKA4	AKAP11	P49841	GSK3B	S483	R476M	476	Missense	distal	-7	no	6.479	6.481	EPSD	TCGA;ICGC	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	Q9UKA4	AKAP11	P49841	GSK3B	S483	N480H	480	Missense	distal	-3	no	6.479	6.685	EPSD	TCGA;ICGC	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	Q9UKA4	AKAP11	P49841	GSK3B	S673	C676G	676	Missense	distal	3	no	5.835	6.095	EPSD	TCGA;ICGC;COSMIC	6.007	Gain
CMGC_GSK_GSK3B_ST	Q9UKA4	AKAP11	P49841	GSK3B	T915	T915P	915	Missense	central	0	yes	8.349	0.000	EPSD	TCGA;ICGC;COSMIC	6.007	Loss
CMGC_GSK_GSK3B_ST	Q9UKA4	AKAP11	P49841	GSK3B	T915	K912N	912	Missense	distal	-3	no	8.349	8.231	EPSD	TCGA;ICGC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	Q9UKA4	AKAP11	P49841	GSK3B	T915	L911F	911	Missense	distal	-4	no	8.349	8.546	EPSD	TCGA;ICGC;COSMIC	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	Q9UKA4	AKAP11	P49841	GSK3B	T915	S919F	919	Missense	distal	4	no	8.349	4.735	EPSD	TCGA;ICGC;COSMIC;CCLE	6.007	Loss
CMGC_GSK_GSK3B_ST	Q9UKA4	AKAP11	P49841	GSK3B	T981	S985P	985	Missense	distal	4	no	11.141	8.170	EPSD	TCGA;ICGC;COSMIC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	Q9UKA4	AKAP11	P49841	GSK3B	T981	F988C	988	Missense	distal	7	no	11.141	11.456	EPSD	TCGA;ICGC;COSMIC	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	Q9UKA4	AKAP11	P49841	GSK3B	S985	P989S	989	Missense	distal	4	no	8.661	11.632	EPSD	TCGA;ICGC;COSMIC	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	Q9UKA4	AKAP11	P49841	GSK3B	S985	S985P	985	Missense	central	0	yes	8.661	0.000	EPSD	TCGA;ICGC;COSMIC	6.007	Loss
CMGC_GSK_GSK3B_ST	Q9UKA4	AKAP11	P49841	GSK3B	S985	F988C	988	Missense	distal	3	no	8.661	8.656	EPSD	TCGA;ICGC;COSMIC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	Q9UKA4	AKAP11	P49841	GSK3B	S1019	S1013F	1013	Missense	distal	-6	no	6.011	5.957	EPSD	TCGA;ICGC;COSMIC	6.007	Loss
CMGC_GSK_GSK3B_ST	Q9UKA4	AKAP11	P49841	GSK3B	S1019	H1016Y	1016	Missense	distal	-3	no	6.011	6.039	EPSD	TCGA;ICGC;COSMIC	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	Q9UKA4	AKAP11	P49841	GSK3B	T1136	S1139C	1139	Missense	distal	3	no	10.135	9.920	PhosphoSitePlus;EPSD	TCGA;ICGC;COSMIC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	Q9UKA4	AKAP11	P49841	GSK3B	T1140	S1139C	1139	Missense	proximal	-1	no	9.758	9.722	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	Q9UKA4	AKAP11	P49841	GSK3B	S1144	S1139C	1139	Missense	distal	-5	no	6.613	7.132	EPSD	TCGA;ICGC;COSMIC	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	Q9UKA4	AKAP11	P49841	GSK3B	S1240	R1239I	1239	Missense	proximal	-1	no	6.265	6.253	EPSD	TCGA;ICGC;COSMIC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	Q9UKA4	AKAP11	P49841	GSK3B	S1240	S1242L	1242	Missense	proximal	2	no	6.265	6.325	EPSD	TCGA;ICGC;COSMIC;GDSC;CCLE	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	Q9UKA4	AKAP11	P49841	GSK3B	S1242	S1249L	1249	Missense	distal	7	no	6.052	6.038	EPSD	TCGA;ICGC;COSMIC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	Q9UKA4	AKAP11	P49841	GSK3B	S1242	R1239I	1239	Missense	distal	-3	no	6.052	5.996	EPSD	TCGA;ICGC;COSMIC	6.007	Loss
CMGC_GSK_GSK3B_ST	Q9UKA4	AKAP11	P49841	GSK3B	S1242	S1242L	1242	Missense	central	0	yes	6.052	0.000	EPSD	TCGA;ICGC;COSMIC;GDSC;CCLE	6.007	Loss
CMGC_GSK_GSK3B_ST	Q9UKA4	AKAP11	P49841	GSK3B	S1460	K1467Q	1467	Missense	distal	7	no	7.045	7.204	EPSD	TCGA;ICGC;COSMIC	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	Q9UKA4	AKAP11	P49841	GSK3B	S1460	S1464N	1464	Missense	distal	4	no	7.045	3.435	EPSD	TCGA;ICGC;COSMIC	6.007	Loss
CMGC_GSK_GSK3B_ST	Q9UKA4	AKAP11	P49841	GSK3B	S1483	G1479D	1479	Missense	distal	-4	no	6.866	6.694	EPSD	TCGA;ICGC;COSMIC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	Q9UKA4	AKAP11	P49841	GSK3B	S1615	S1619C	1619	Missense	distal	4	no	7.370	1.237	EPSD	TCGA;ICGC;COSMIC	6.007	Loss
CMGC_GSK_GSK3B_ST	Q9NW38	FANCL	P49841	GSK3B	S77	M74V	74	Missense	distal	-3	no	8.094	8.289	EPSD	TCGA;ICGC;COSMIC	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	P56524	HDAC4	P49841	GSK3B	S210	G204R	204	Missense	distal	-6	no	9.356	9.283	EPSD	TCGA;COSMIC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	P56524	HDAC4	P49841	GSK3B	S215	S222L	222	Missense	distal	7	no	10.763	10.749	EPSD	TCGA;COSMIC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	P56524	HDAC4	P49841	GSK3B	S266	R270C	270	Missense	distal	4	no	6.769	3.674	EPSD	TCGA;COSMIC;CCLE	6.007	Loss
CMGC_GSK_GSK3B_ST	P56524	HDAC4	P49841	GSK3B	S266	R263K	263	Missense	distal	-3	no	6.769	6.624	EPSD	TCGA;COSMIC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	P56524	HDAC4	P49841	GSK3B	S294	S290F	290	Missense	distal	-4	no	8.269	7.115	EPSD	TCGA;COSMIC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	P56524	HDAC4	P49841	GSK3B	S294	A295T	295	Missense	proximal	1	no	8.269	8.810	EPSD	TCGA;COSMIC	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	P56524	HDAC4	P49841	GSK3B	S294	P300S	300	Missense	distal	6	no	8.269	8.267	EPSD	TCGA;COSMIC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	P56524	HDAC4	P49841	GSK3B	S294	G299R	299	Missense	distal	5	no	8.269	8.543	EPSD	TCGA;COSMIC	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	P56524	HDAC4	P49841	GSK3B	S298	A295T	295	Missense	distal	-3	no	10.108	10.112	EPSD;PhosphoSitePlus	TCGA;COSMIC	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	P56524	HDAC4	P49841	GSK3B	S298	P300S	300	Missense	proximal	2	no	10.108	9.664	EPSD;PhosphoSitePlus	TCGA;COSMIC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	P56524	HDAC4	P49841	GSK3B	S298	G299R	299	Missense	proximal	1	no	10.108	10.982	EPSD;PhosphoSitePlus	TCGA;COSMIC	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	P56524	HDAC4	P49841	GSK3B	S302	S309N	309	Missense	distal	7	no	10.984	11.107	PhosphoSitePlus;EPSD	TCGA;COSMIC	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	P56524	HDAC4	P49841	GSK3B	S302	A295T	295	Missense	distal	-7	no	10.984	10.989	PhosphoSitePlus;EPSD	TCGA;COSMIC	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	P56524	HDAC4	P49841	GSK3B	S302	P300S	300	Missense	proximal	-2	no	10.984	10.728	PhosphoSitePlus;EPSD	TCGA;COSMIC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	P56524	HDAC4	P49841	GSK3B	S302	S306N	306	Missense	distal	4	no	10.984	7.374	PhosphoSitePlus;EPSD	TCGA	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	P56524	HDAC4	P49841	GSK3B	S302	G299R	299	Missense	distal	-3	no	10.984	11.157	PhosphoSitePlus;EPSD	TCGA;COSMIC	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	P56524	HDAC4	P49841	GSK3B	S307	S309N	309	Missense	proximal	2	no	6.805	6.273	EPSD	TCGA;COSMIC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	P56524	HDAC4	P49841	GSK3B	S307	P300S	300	Missense	distal	-7	no	6.805	6.807	EPSD	TCGA;COSMIC	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	P56524	HDAC4	P49841	GSK3B	S307	A312V	312	Missense	distal	5	no	6.805	6.379	EPSD	TCGA;COSMIC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	P56524	HDAC4	P49841	GSK3B	S307	S306N	306	Missense	proximal	-1	no	6.805	6.867	EPSD	TCGA	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	P56524	HDAC4	P49841	GSK3B	S307	V310I	310	Missense	distal	3	no	6.805	6.593	EPSD	TCGA;COSMIC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	P56524	HDAC4	P49841	GSK3B	S348	P352L	352	Missense	distal	4	no	6.267	6.521	EPSD	TCGA;COSMIC	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	P56524	HDAC4	P49841	GSK3B	S348	S350F	350	Missense	proximal	2	no	6.267	5.923	EPSD	TCGA;COSMIC	6.007	Loss
CMGC_GSK_GSK3B_ST	P56524	HDAC4	P49841	GSK3B	S348	S348L	348	Missense	central	0	yes	6.267	0.000	EPSD	TCGA;COSMIC;CCLE	6.007	Loss
CMGC_GSK_GSK3B_ST	P56524	HDAC4	P49841	GSK3B	S348	T355M	355	Missense	distal	7	no	6.267	6.695	EPSD	TCGA;COSMIC	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	P56524	HDAC4	P49841	GSK3B	T394	G390S	390	Missense	distal	-4	no	9.322	9.750	EPSD	TCGA;COSMIC	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	P56524	HDAC4	P49841	GSK3B	S400	R404L	404	Missense	distal	4	no	7.430	7.750	EPSD	TCGA;COSMIC	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	P56524	HDAC4	P49841	GSK3B	S400	R404W	404	Missense	distal	4	no	7.430	6.519	EPSD	TCGA;COSMIC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	P56524	HDAC4	P49841	GSK3B	S628	G623D	623	Missense	distal	-5	no	8.322	8.129	EPSD	TCGA;COSMIC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	P56524	HDAC4	P49841	GSK3B	S628	A630V	630	Missense	proximal	2	no	8.322	8.045	EPSD	TCGA;COSMIC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	P56524	HDAC4	P49841	GSK3B	S633	A630V	630	Missense	distal	-3	no	8.220	8.366	EPSD	TCGA;COSMIC	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	O95997	PTTG1	P49841	GSK3B	S103	S102N	102	Missense	proximal	-1	no	7.048	7.110	EPSD	TCGA;ICGC;COSMIC	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	O95997	PTTG1	P49841	GSK3B	S103	A110V	110	Missense	distal	7	no	7.048	7.126	EPSD	TCGA;ICGC;COSMIC	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	O95997	PTTG1	P49841	GSK3B	S165	P170S	170	Missense	distal	5	no	7.639	6.685	EPSD	TCGA;ICGC;COSMIC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	O95997	PTTG1	P49841	GSK3B	S165	P166S	166	Missense	proximal	1	no	7.639	3.794	EPSD	TCGA;ICGC;COSMIC	6.007	Loss
CMGC_GSK_GSK3B_ST	O95997	PTTG1	P49841	GSK3B	S165	P164H	164	Missense	proximal	-1	no	7.639	7.531	EPSD	TCGA;ICGC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	O95997	PTTG1	P49841	GSK3B	S171	S176C	176	Missense	distal	5	no	7.768	6.528	EPSD	TCGA;ICGC;COSMIC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	O95997	PTTG1	P49841	GSK3B	S171	P170S	170	Missense	proximal	-1	no	7.768	7.712	EPSD	TCGA;ICGC;COSMIC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	O95997	PTTG1	P49841	GSK3B	S171	P166S	166	Missense	distal	-5	no	7.768	7.925	EPSD	TCGA;ICGC;COSMIC	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	O95997	PTTG1	P49841	GSK3B	S171	E175K	175	Missense	distal	4	no	7.768	6.586	EPSD	TCGA;ICGC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	O95997	PTTG1	P49841	GSK3B	S171	P164H	164	Missense	distal	-7	no	7.768	7.788	EPSD	TCGA;ICGC	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	O95997	PTTG1	P49841	GSK3B	S181	S176C	176	Missense	distal	-5	no	5.676	6.195	EPSD	TCGA;ICGC;COSMIC	6.007	Gain
CMGC_GSK_GSK3B_ST	O95997	PTTG1	P49841	GSK3B	S184	S187L	187	Missense	distal	3	no	6.074	5.773	PhosphoSitePlus;EPSD	TCGA;ICGC;COSMIC	6.007	Loss
CMGC_GSK_GSK3B_ST	P14618	PKM	P49841	GSK3B	S6	S2L	2	Missense	distal	-4	no	6.814	5.464	EPSD	TCGA;COSMIC	6.007	Loss
CMGC_GSK_GSK3B_ST	P14618	PKM	P49841	GSK3B	S6	F12Y	12	Missense	distal	6	no	6.814	6.821	EPSD	TCGA;ICGC;COSMIC	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	P14618	PKM	P49841	GSK3B	S37	R43P	43	Missense	distal	6	no	9.277	9.284	EPSD	TCGA;ICGC;COSMIC	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	P14618	PKM	P49841	GSK3B	S37	R32C	32	Missense	distal	-5	no	9.277	9.099	EPSD	TCGA;ICGC;COSMIC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	P14618	PKM	P49841	GSK3B	S37	R32H	32	Missense	distal	-5	no	9.277	8.747	EPSD	TCGA;ICGC;COSMIC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	P14618	PKM	P49841	GSK3B	T41	R43P	43	Missense	proximal	2	no	5.631	6.057	EPSD	TCGA;ICGC;COSMIC	6.007	Gain
CMGC_GSK_GSK3B_ST	P14618	PKM	P49841	GSK3B	S346	N350S	350	Missense	distal	4	no	3.379	6.990	EPSD	TCGA;COSMIC	6.007	Gain
CMGC_GSK_GSK3B_ST	P14618	PKM	P49841	GSK3B	S406	R400Q	400	Missense	distal	-6	no	6.023	6.076	EPSD	TCGA	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	P49841	GSK3B	P49841	GSK3B	S25	Q19R	19	Missense	distal	-6	no	6.701	6.649	EPSD	TCGA	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	P49841	GSK3B	P49841	GSK3B	S25	S25N	25	Missense	central	0	yes	6.701	0.000	EPSD	TCGA;ICGC	6.007	Loss
CMGC_GSK_GSK3B_ST	P49841	GSK3B	P49841	GSK3B	S25	A22S	22	Missense	distal	-3	no	6.701	6.681	EPSD	TCGA;ICGC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	P49841	GSK3B	P49841	GSK3B	T43	D49N	49	Missense	distal	6	no	7.636	7.637	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	P49841	GSK3B	P49841	GSK3B	S55	T59I	59	Missense	distal	4	no	7.192	4.739	EPSD	TCGA;ICGC;COSMIC	6.007	Loss
CMGC_GSK_GSK3B_ST	P49841	GSK3B	P49841	GSK3B	S55	D49N	49	Missense	distal	-6	no	7.192	7.215	EPSD	TCGA;ICGC;COSMIC	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	P49841	GSK3B	P49841	GSK3B	S215	Y216C	216	Missense	proximal	1	no	7.507	6.502	EPSD	TCGA;ICGC;COSMIC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	P49841	GSK3B	P49841	GSK3B	S215	S215L	215	Missense	central	0	yes	7.507	0.000	EPSD	TCGA;ICGC;COSMIC	6.007	Loss
CMGC_GSK_GSK3B_ST	P49841	GSK3B	P49841	GSK3B	S219	Y216C	216	Missense	distal	-3	no	6.818	6.781	EPSD	TCGA;ICGC;COSMIC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	P49841	GSK3B	P49841	GSK3B	S219	S215L	215	Missense	distal	-4	no	6.818	5.468	EPSD	TCGA;ICGC;COSMIC	6.007	Loss
CMGC_GSK_GSK3B_ST	Q96R06	SPAG5	P49841	GSK3B	S8	K6Q	6	Missense	proximal	-2	no	6.916	7.005	EPSD	TCGA;ICGC;COSMIC	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	Q96R06	SPAG5	P49841	GSK3B	S10	K6Q	6	Missense	distal	-4	no	7.167	7.202	EPSD	TCGA;ICGC;COSMIC	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	Q96R06	SPAG5	P49841	GSK3B	S12	G18R	18	Missense	distal	6	no	6.787	6.786	EPSD	TCGA;ICGC;COSMIC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	Q96R06	SPAG5	P49841	GSK3B	S12	K6Q	6	Missense	distal	-6	no	6.787	6.846	EPSD	TCGA;ICGC;COSMIC	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	Q96R06	SPAG5	P49841	GSK3B	S14	G18R	18	Missense	distal	4	no	6.677	6.882	EPSD	TCGA;ICGC;COSMIC	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	Q96R06	SPAG5	P49841	GSK3B	T17	G18R	18	Missense	proximal	1	no	5.208	6.083	EPSD	TCGA;ICGC;COSMIC	6.007	Gain
CMGC_GSK_GSK3B_ST	Q96R06	SPAG5	P49841	GSK3B	S39	L36F	36	Missense	distal	-3	no	6.758	6.815	EPSD	TCGA;ICGC;COSMIC	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	Q96R06	SPAG5	P49841	GSK3B	S39	R42G	42	Missense	distal	3	no	6.758	7.173	EPSD	TCGA;ICGC;COSMIC	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	Q96R06	SPAG5	P49841	GSK3B	S43	S48L	48	Missense	distal	5	no	8.603	8.276	EPSD	TCGA;ICGC;COSMIC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	Q96R06	SPAG5	P49841	GSK3B	S43	L36F	36	Missense	distal	-7	no	8.603	8.613	EPSD	TCGA;ICGC;COSMIC	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	Q96R06	SPAG5	P49841	GSK3B	S43	R42G	42	Missense	proximal	-1	no	8.603	8.747	EPSD	TCGA;ICGC;COSMIC	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	Q96R06	SPAG5	P49841	GSK3B	S48	S48L	48	Missense	central	0	yes	7.090	0.000	EPSD	TCGA;ICGC;COSMIC	6.007	Loss
CMGC_GSK_GSK3B_ST	Q96R06	SPAG5	P49841	GSK3B	S48	R42G	42	Missense	distal	-6	no	7.090	7.164	EPSD	TCGA;ICGC;COSMIC	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	Q96R06	SPAG5	P49841	GSK3B	S66	N63S	63	Missense	distal	-3	no	6.872	6.967	EPSD	TCGA;COSMIC	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	Q96R06	SPAG5	P49841	GSK3B	T76	F83L	83	Missense	distal	7	no	6.777	6.685	EPSD	TCGA;ICGC;COSMIC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	Q96R06	SPAG5	P49841	GSK3B	S86	S87P	87	Missense	proximal	1	no	3.461	7.306	EPSD	TCGA;ICGC;COSMIC	6.007	Gain
CMGC_GSK_GSK3B_ST	Q96R06	SPAG5	P49841	GSK3B	S110	S110C	110	Missense	central	0	yes	6.052	0.000	EPSD	TCGA;ICGC;COSMIC	6.007	Loss
CMGC_GSK_GSK3B_ST	Q96R06	SPAG5	P49841	GSK3B	S110	P106L	106	Missense	distal	-4	no	6.052	5.265	EPSD	TCGA;ICGC;COSMIC	6.007	Loss
CMGC_GSK_GSK3B_ST	Q96R06	SPAG5	P49841	GSK3B	T111	S110C	110	Missense	proximal	-1	no	10.369	10.333	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	Q96R06	SPAG5	P49841	GSK3B	T111	P106L	106	Missense	distal	-5	no	10.369	10.634	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	Q96R06	SPAG5	P49841	GSK3B	S135	Q139R	139	Missense	distal	4	no	5.993	6.519	EPSD	TCGA;ICGC;COSMIC	6.007	Gain
CMGC_GSK_GSK3B_ST	Q96R06	SPAG5	P49841	GSK3B	S135	L132I	132	Missense	distal	-3	no	5.993	6.097	EPSD	TCGA;ICGC	6.007	Gain
CMGC_GSK_GSK3B_ST	Q96R06	SPAG5	P49841	GSK3B	S205	E203G	203	Missense	proximal	-2	no	6.983	6.968	EPSD	TCGA;ICGC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	Q96R06	SPAG5	P49841	GSK3B	S205	P209L	209	Missense	distal	4	no	6.983	7.236	EPSD	TCGA;ICGC;COSMIC	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	Q96R06	SPAG5	P49841	GSK3B	S205	H200N	200	Missense	distal	-5	no	6.983	6.524	EPSD	TCGA;ICGC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	Q96R06	SPAG5	P49841	GSK3B	S249	A253V	253	Missense	distal	4	no	6.901	6.923	EPSD	TCGA;ICGC;COSMIC	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	Q96R06	SPAG5	P49841	GSK3B	S341	K348N	348	Missense	distal	7	no	6.054	6.246	EPSD	TCGA;ICGC;COSMIC	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	Q96R06	SPAG5	P49841	GSK3B	T377	D371Y	371	Missense	distal	-6	no	6.240	6.179	EPSD	TCGA;ICGC;COSMIC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	Q96R06	SPAG5	P49841	GSK3B	T389	S391L	391	Missense	proximal	2	no	7.234	7.293	EPSD	TCGA;ICGC;COSMIC	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	Q96R06	SPAG5	P49841	GSK3B	T389	P390H	390	Missense	proximal	1	no	7.234	3.533	EPSD	TCGA;ICGC;COSMIC	6.007	Loss
CMGC_GSK_GSK3B_ST	Q96R06	SPAG5	P49841	GSK3B	S397	S391L	391	Missense	distal	-6	no	6.387	6.386	EPSD	TCGA;ICGC;COSMIC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	Q96R06	SPAG5	P49841	GSK3B	S397	P390H	390	Missense	distal	-7	no	6.387	6.407	EPSD	TCGA;ICGC;COSMIC	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	Q96R06	SPAG5	P49841	GSK3B	T466	P464S	464	Missense	proximal	-2	no	6.440	6.183	EPSD	TCGA;ICGC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	Q96R06	SPAG5	P49841	GSK3B	T466	P462S	462	Missense	distal	-4	no	6.440	7.003	EPSD	TCGA;ICGC;COSMIC	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	Q96R06	SPAG5	P49841	GSK3B	T466	Q472H	472	Missense	distal	6	no	6.440	6.433	EPSD	TCGA;ICGC;COSMIC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	Q96R06	SPAG5	P49841	GSK3B	S559	L560R	560	Missense	proximal	1	no	6.077	6.618	EPSD	TCGA;ICGC;COSMIC	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	Q96R06	SPAG5	P49841	GSK3B	S559	A555T	555	Missense	distal	-4	no	6.077	6.902	EPSD	TCGA;ICGC;COSMIC	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	Q96R06	SPAG5	P49841	GSK3B	T656	S660G	660	Missense	distal	4	no	6.589	3.346	EPSD	TCGA;ICGC;COSMIC	6.007	Loss
CMGC_GSK_GSK3B_ST	Q96R06	SPAG5	P49841	GSK3B	T656	R663Q	663	Missense	distal	7	no	6.589	6.241	EPSD	TCGA;ICGC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	Q96R06	SPAG5	P49841	GSK3B	T937	S936A	936	Missense	proximal	-1	no	6.516	6.362	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	Q96R06	SPAG5	P49841	GSK3B	T937	V939L	939	Missense	proximal	2	no	6.516	6.845	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	Q96R06	SPAG5	P49841	GSK3B	T950	R951P	951	Missense	proximal	1	no	4.849	7.169	EPSD	TCGA;ICGC;COSMIC	6.007	Gain
CMGC_GSK_GSK3B_ST	Q96R06	SPAG5	P49841	GSK3B	T963	P964Q	964	Missense	proximal	1	no	6.325	3.056	EPSD	TCGA;ICGC;COSMIC	6.007	Loss
CMGC_GSK_GSK3B_ST	Q96R06	SPAG5	P49841	GSK3B	T978	M973I	973	Missense	distal	-5	no	6.582	6.753	PhosphoSitePlus;EPSD	TCGA;ICGC;COSMIC	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	Q96R06	SPAG5	P49841	GSK3B	T978	E972D	972	Missense	distal	-6	no	6.582	6.619	PhosphoSitePlus;EPSD	TCGA;ICGC	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	O60341	KDM1A	P49841	GSK3B	T841	A846V	846	Missense	distal	5	no	7.729	7.302	EPSD	TCGA;ICGC;COSMIC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	Q9Y2X9	ZNF281	P49841	GSK3B	S160	E167V	167	Missense	distal	7	no	7.051	7.437	EPSD	TCGA;ICGC;COSMIC	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	Q9Y2X9	ZNF281	P49841	GSK3B	S160	E158D	158	Missense	proximal	-2	no	7.051	7.138	EPSD	TCGA;ICGC	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	Q9Y2X9	ZNF281	P49841	GSK3B	S255	H261R	261	Missense	distal	6	no	8.769	8.775	EPSD	TCGA;ICGC;COSMIC	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	Q9Y2X9	ZNF281	P49841	GSK3B	S255	H261Q	261	Missense	distal	6	no	8.769	8.775	EPSD	TCGA;ICGC;COSMIC	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	Q9Y2X9	ZNF281	P49841	GSK3B	S255	K259R	259	Missense	distal	4	no	8.769	8.934	EPSD	TCGA;ICGC;COSMIC	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	Q9Y2X9	ZNF281	P49841	GSK3B	S484	K477E	477	Missense	distal	-7	no	6.141	6.152	EPSD	TCGA;ICGC;COSMIC	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	Q9Y2X9	ZNF281	P49841	GSK3B	S638	S638L	638	Missense	central	0	yes	7.944	0.000	PhosphoSitePlus	TCGA;ICGC;COSMIC	6.007	Loss
CMGC_GSK_GSK3B_ST	Q9Y2X9	ZNF281	P49841	GSK3B	S638	R632Q	632	Missense	distal	-6	no	7.944	7.997	PhosphoSitePlus	TCGA;ICGC;COSMIC	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	Q9Y2X9	ZNF281	P49841	GSK3B	S651	G653D	653	Missense	proximal	2	no	7.208	7.558	EPSD	TCGA;ICGC;COSMIC	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	Q9Y2X9	ZNF281	P49841	GSK3B	S651	P652L	652	Missense	proximal	1	no	7.208	4.347	EPSD	TCGA;ICGC;COSMIC	6.007	Loss
CMGC_GSK_GSK3B_ST	Q9Y2X9	ZNF281	P49841	GSK3B	S651	P652S	652	Missense	proximal	1	no	7.208	3.363	EPSD	TCGA;ICGC;COSMIC	6.007	Loss
CMGC_GSK_GSK3B_ST	Q9Y2X9	ZNF281	P49841	GSK3B	S837	Q833E	833	Missense	distal	-4	no	6.375	6.607	EPSD	TCGA;ICGC;COSMIC	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	Q9Y2X9	ZNF281	P49841	GSK3B	S876	S883G	883	Missense	distal	7	no	6.694	6.714	EPSD	TCGA;ICGC	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	Q9Y2X9	ZNF281	P49841	GSK3B	S879	S883G	883	Missense	distal	4	no	7.940	4.697	EPSD	TCGA;ICGC	6.007	Loss
CMGC_GSK_GSK3B_ST	Q9Y2X9	ZNF281	P49841	GSK3B	T884	S883G	883	Missense	proximal	-1	no	7.110	7.117	EPSD	TCGA;ICGC	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	Q9Y2X9	ZNF281	P49841	GSK3B	T888	S883G	883	Missense	distal	-5	no	6.399	6.865	EPSD	TCGA;ICGC	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	P38936	CDKN1A	P49841	GSK3B	S27	D33N	33	Missense	distal	6	no	8.454	8.455	EPSD	TCGA;ICGC;COSMIC	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	P38936	CDKN1A	P49841	GSK3B	S27	R32H	32	Missense	distal	5	no	8.454	7.465	EPSD	TCGA;ICGC;COSMIC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	P38936	CDKN1A	P49841	GSK3B	T57	G61V	61	Missense	distal	4	no	5.880	6.733	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	6.007	Gain
CMGC_GSK_GSK3B_ST	P38936	CDKN1A	P49841	GSK3B	S98	R94W	94	Missense	distal	-4	no	6.719	5.889	EPSD	TCGA;ICGC;COSMIC	6.007	Loss
CMGC_GSK_GSK3B_ST	P38936	CDKN1A	P49841	GSK3B	S98	R93S	93	Missense	distal	-5	no	6.719	6.022	EPSD	TCGA;ICGC;COSMIC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	P38936	CDKN1A	P49841	GSK3B	S98	R94P	94	Missense	distal	-4	no	6.719	7.342	EPSD	TCGA;ICGC;COSMIC	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	P38936	CDKN1A	P49841	GSK3B	S98	P95S	95	Missense	distal	-3	no	6.719	6.836	EPSD	TCGA;ICGC;COSMIC	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	P38936	CDKN1A	P49841	GSK3B	S114	H110P	110	Missense	distal	-4	no	6.439	6.963	PhosphoSitePlus;EPSD	TCGA;ICGC	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	P38936	CDKN1A	P49841	GSK3B	S130	D136H	136	Missense	distal	6	no	7.588	7.585	EPSD	TCGA;ICGC;COSMIC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	P38936	CDKN1A	P49841	GSK3B	S130	G132C	132	Missense	proximal	2	no	7.588	7.354	EPSD	TCGA;ICGC;COSMIC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	P38936	CDKN1A	P49841	GSK3B	S130	E128K	128	Missense	proximal	-2	no	7.588	7.556	EPSD	TCGA;ICGC;COSMIC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	P38936	CDKN1A	P49841	GSK3B	S130	G135A	135	Missense	distal	5	no	7.588	7.471	EPSD	TCGA	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	Q9BZS1	FOXP3	P49841	GSK3B	S418	R420M	420	Missense	proximal	2	no	7.903	7.313	EPSD	TCGA	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	Q9BZS1	FOXP3	P49841	GSK3B	S418	L411P	411	Missense	distal	-7	no	7.903	7.901	EPSD	TCGA;COSMIC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	O43602	DCX	P49841	GSK3B	S28	S28F	28	Missense	central	0	yes	9.996	0.000	EPSD	TCGA;ICGC	6.007	Loss
CMGC_GSK_GSK3B_ST	O43602	DCX	P49841	GSK3B	S161	A163T	163	Missense	proximal	2	no	6.817	6.935	EPSD	TCGA;ICGC	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	O43602	DCX	P49841	GSK3B	S161	A163V	163	Missense	proximal	2	no	6.817	6.540	EPSD	TCGA;ICGC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	O43602	DCX	P49841	GSK3B	S354	D348Y	348	Missense	distal	-6	no	7.661	7.600	EPSD	TCGA;ICGC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	P22670	RFX1	P49841	GSK3B	S60	P63S	63	Missense	distal	3	no	6.271	6.253	EPSD	TCGA;ICGC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	P22670	RFX1	P49841	GSK3B	S120	T124S	124	Missense	distal	4	no	10.017	10.886	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	P22670	RFX1	P49841	GSK3B	S120	T115I	115	Missense	distal	-5	no	10.017	10.200	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	P22670	RFX1	P49841	GSK3B	S120	E118D	118	Missense	proximal	-2	no	10.017	10.104	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	P22670	RFX1	P49841	GSK3B	T124	V130I	130	Missense	distal	6	no	6.700	6.710	PhosphoSitePlus;EPSD	TCGA;ICGC;COSMIC	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	P22670	RFX1	P49841	GSK3B	T124	E118D	118	Missense	distal	-6	no	6.700	6.737	PhosphoSitePlus;EPSD	TCGA;ICGC;COSMIC	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	P22670	RFX1	P49841	GSK3B	T128	V130I	130	Missense	proximal	2	no	5.993	6.323	EPSD	TCGA;ICGC;COSMIC	6.007	Gain
CMGC_GSK_GSK3B_ST	P22670	RFX1	P49841	GSK3B	T128	T124S	124	Missense	distal	-4	no	5.993	6.329	EPSD	TCGA;ICGC;COSMIC	6.007	Gain
CMGC_GSK_GSK3B_ST	P22670	RFX1	P49841	GSK3B	S159	V158M	158	Missense	proximal	-1	no	7.671	7.572	EPSD	TCGA;ICGC;COSMIC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	P22670	RFX1	P49841	GSK3B	S209	P210L	210	Missense	proximal	1	no	6.371	3.510	EPSD	TCGA;ICGC;COSMIC	6.007	Loss
CMGC_GSK_GSK3B_ST	P22670	RFX1	P49841	GSK3B	T253	Q251H	251	Missense	proximal	-2	no	6.227	6.167	EPSD	TCGA;ICGC;COSMIC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	P22670	RFX1	P49841	GSK3B	T253	R247S	247	Missense	distal	-6	no	6.227	6.284	EPSD	TCGA;ICGC;COSMIC	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	P22670	RFX1	P49841	GSK3B	S453	E447Q	447	Missense	distal	-6	no	7.332	7.389	EPSD	TCGA;ICGC;COSMIC	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	P22670	RFX1	P49841	GSK3B	S453	V452M	452	Missense	proximal	-1	no	7.332	7.233	EPSD	TCGA;ICGC;COSMIC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	P08238	HSP90AB1	P49841	GSK3B	S63	Y56C	56	Missense	distal	-7	no	6.915	6.909	EPSD	TCGA;ICGC;COSMIC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	P08238	HSP90AB1	P49841	GSK3B	S63	S67I	67	Missense	distal	4	no	6.915	3.593	EPSD	TCGA;ICGC	6.007	Loss
CMGC_GSK_GSK3B_ST	P08238	HSP90AB1	P49841	GSK3B	S108	A112S	112	Missense	distal	4	no	5.099	7.510	EPSD	TCGA;ICGC;COSMIC	6.007	Gain
CMGC_GSK_GSK3B_ST	P08238	HSP90AB1	P49841	GSK3B	S669	S665C	665	Missense	distal	-4	no	6.872	4.757	EPSD	TCGA;ICGC;COSMIC	6.007	Loss
CMGC_GSK_GSK3B_ST	P08238	HSP90AB1	P49841	GSK3B	S669	H676Y	676	Missense	distal	7	no	6.872	6.688	EPSD	TCGA;ICGC;COSMIC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	P08238	HSP90AB1	P49841	GSK3B	S669	A662T	662	Missense	distal	-7	no	6.872	6.876	EPSD	TCGA;ICGC;COSMIC;CCLE	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	P08238	HSP90AB1	P49841	GSK3B	S718	V723A	723	Missense	distal	5	no	5.809	6.235	PhosphoSitePlus	TCGA;ICGC	6.007	Gain
CMGC_GSK_GSK3B_ST	Q15797	SMAD1	P49841	GSK3B	S11	A13T	13	Missense	proximal	2	no	6.040	6.158	EPSD	TCGA;ICGC;COSMIC	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	Q15797	SMAD1	P49841	GSK3B	S132	R129K	129	Missense	distal	-3	no	7.361	7.216	EPSD	TCGA;ICGC;COSMIC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	Q15797	SMAD1	P49841	GSK3B	S132	L139V	139	Missense	distal	7	no	7.361	7.801	EPSD	TCGA;ICGC;COSMIC	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	Q15797	SMAD1	P49841	GSK3B	S187	S190T	190	Missense	distal	3	no	9.456	9.424	EPSD	TCGA;ICGC;COSMIC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	Q15797	SMAD1	P49841	GSK3B	S195	G197V	197	Missense	proximal	2	no	11.405	11.394	EPSD	TCGA;ICGC;COSMIC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	Q15797	SMAD1	P49841	GSK3B	S195	S190T	190	Missense	distal	-5	no	11.405	11.694	EPSD	TCGA;ICGC;COSMIC	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	Q15797	SMAD1	P49841	GSK3B	T202	G197V	197	Missense	distal	-5	no	9.463	9.577	PhosphoSitePlus	TCGA;ICGC;COSMIC	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	Q15797	SMAD1	P49841	GSK3B	S214	D221G	221	Missense	distal	7	no	8.465	8.430	EPSD	TCGA;ICGC;COSMIC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	Q15853	USF2	P49841	GSK3B	S151	N152S	152	Missense	proximal	1	no	6.172	7.847	EPSD	TCGA;ICGC;COSMIC	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	Q15853	USF2	P49841	GSK3B	S151	P149S	149	Missense	proximal	-2	no	6.172	5.916	EPSD	TCGA;ICGC;COSMIC	6.007	Loss
CMGC_GSK_GSK3B_ST	Q15853	USF2	P49841	GSK3B	S155	N152S	152	Missense	distal	-3	no	9.261	9.356	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	Q15853	USF2	P49841	GSK3B	S155	P149S	149	Missense	distal	-6	no	9.261	9.240	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	Q15853	USF2	P49841	GSK3B	S155	S162N	162	Missense	distal	7	no	9.261	9.384	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	Q15853	USF2	P49841	GSK3B	S222	I225V	225	Missense	distal	3	no	8.345	8.557	EPSD	TCGA;ICGC;COSMIC	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	Q15853	USF2	P49841	GSK3B	S222	P223L	223	Missense	proximal	1	no	8.345	5.484	EPSD	TCGA;ICGC;COSMIC	6.007	Loss
CMGC_GSK_GSK3B_ST	Q15853	USF2	P49841	GSK3B	S222	R217Q	217	Missense	distal	-5	no	8.345	7.790	EPSD	TCGA;ICGC;COSMIC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	Q15853	USF2	P49841	GSK3B	S222	A215T	215	Missense	distal	-7	no	8.345	8.349	EPSD	TCGA;ICGC;COSMIC	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	Q15853	USF2	P49841	GSK3B	T230	I225V	225	Missense	distal	-5	no	8.881	8.988	PhosphoSitePlus;EPSD	TCGA;ICGC;COSMIC	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	Q15853	USF2	P49841	GSK3B	T230	P223L	223	Missense	distal	-7	no	8.881	8.882	PhosphoSitePlus;EPSD	TCGA;ICGC;COSMIC	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	Q07820	MCL1	P49841	GSK3B	S121	E123K	123	Missense	proximal	2	no	7.881	7.921	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	Q07820	MCL1	P49841	GSK3B	S150	T154I	154	Missense	distal	4	no	6.613	4.160	EPSD	TCGA;ICGC;COSMIC	6.007	Loss
CMGC_GSK_GSK3B_ST	Q07820	MCL1	P49841	GSK3B	S155	S162W	162	Missense	distal	7	no	6.717	7.264	EPSD	TCGA;ICGC;COSMIC	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	Q07820	MCL1	P49841	GSK3B	S155	T154I	154	Missense	proximal	-1	no	6.717	6.643	EPSD	TCGA;ICGC;COSMIC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	Q07820	MCL1	P49841	GSK3B	S159	S162W	162	Missense	distal	3	no	9.113	9.001	PhosphoSitePlus;EPSD	TCGA;ICGC;COSMIC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	Q07820	MCL1	P49841	GSK3B	S159	T154I	154	Missense	distal	-5	no	9.113	9.296	PhosphoSitePlus;EPSD	TCGA;ICGC;COSMIC	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	Q07820	MCL1	P49841	GSK3B	T163	S162W	162	Missense	proximal	-1	no	9.133	9.108	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	Q07820	MCL1	P49841	GSK3B	S206	T212I	212	Missense	distal	6	no	7.022	7.020	EPSD	TCGA;ICGC;COSMIC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	P24864	CCNE1	P49841	GSK3B	T77	D83G	83	Missense	distal	6	no	8.454	8.458	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	P24864	CCNE1	P49841	GSK3B	S103	R101K	101	Missense	proximal	-2	no	7.875	7.857	EPSD	TCGA;ICGC;COSMIC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	P24864	CCNE1	P49841	GSK3B	S387	R385T	385	Missense	proximal	-2	no	10.298	10.441	EPSD	TCGA;ICGC;COSMIC	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	P24864	CCNE1	P49841	GSK3B	S387	R385S	385	Missense	proximal	-2	no	10.298	10.414	EPSD	TCGA;ICGC;COSMIC	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	P24864	CCNE1	P49841	GSK3B	S387	A386S	386	Missense	proximal	-1	no	10.298	10.453	EPSD	TCGA;ICGC;COSMIC	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	P24864	CCNE1	P49841	GSK3B	S391	R385S	385	Missense	distal	-6	no	6.714	6.772	EPSD	TCGA;ICGC;COSMIC	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	P24864	CCNE1	P49841	GSK3B	S391	A386S	386	Missense	distal	-5	no	6.714	6.437	EPSD	TCGA;ICGC;COSMIC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	P24864	CCNE1	P49841	GSK3B	S391	T395I	395	Missense	distal	4	no	6.714	4.261	EPSD	TCGA;ICGC;COSMIC	6.007	Loss
CMGC_GSK_GSK3B_ST	P24864	CCNE1	P49841	GSK3B	S391	P396L	396	Missense	distal	5	no	6.714	5.434	EPSD	TCGA;ICGC;COSMIC	6.007	Loss
CMGC_GSK_GSK3B_ST	P24864	CCNE1	P49841	GSK3B	T395	T395I	395	Missense	central	0	yes	9.736	0.000	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	6.007	Loss
CMGC_GSK_GSK3B_ST	P24864	CCNE1	P49841	GSK3B	T395	P396L	396	Missense	proximal	1	no	9.736	6.876	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	Q9BPU6	DPYSL5	P49841	GSK3B	T490	D495Y	495	Missense	distal	5	no	6.275	5.170	EPSD	TCGA;ICGC;COSMIC	6.007	Loss
CMGC_GSK_GSK3B_ST	Q9BPU6	DPYSL5	P49841	GSK3B	T490	V484A	484	Missense	distal	-6	no	6.275	6.353	EPSD	TCGA;ICGC;COSMIC	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	Q9BPU6	DPYSL5	P49841	GSK3B	T490	R489C	489	Missense	proximal	-1	no	6.275	6.376	EPSD	TCGA;ICGC;COSMIC	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	Q9BPU6	DPYSL5	P49841	GSK3B	T509	G508E	508	Missense	proximal	-1	no	6.077	6.058	EPSD	TCGA;ICGC;COSMIC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	Q9BPU6	DPYSL5	P49841	GSK3B	T516	R517W	517	Missense	proximal	1	no	6.248	6.466	PhosphoSitePlus	TCGA;ICGC;COSMIC	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	Q9BPU6	DPYSL5	P49841	GSK3B	T516	R521L	521	Missense	distal	5	no	6.248	5.605	PhosphoSitePlus	TCGA;ICGC;COSMIC	6.007	Loss
CMGC_GSK_GSK3B_ST	Q9BPU6	DPYSL5	P49841	GSK3B	T516	R521W	521	Missense	distal	5	no	6.248	4.946	PhosphoSitePlus	TCGA;ICGC;COSMIC	6.007	Loss
CMGC_GSK_GSK3B_ST	Q9BPU6	DPYSL5	P49841	GSK3B	S534	L535I	535	Missense	proximal	1	no	7.805	6.784	EPSD	TCGA;ICGC;COSMIC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	Q9BPU6	DPYSL5	P49841	GSK3B	S534	E530A	530	Missense	distal	-4	no	7.805	7.242	EPSD	TCGA;ICGC;COSMIC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	Q9BPU6	DPYSL5	P49841	GSK3B	S534	G537C	537	Missense	distal	3	no	7.805	7.545	EPSD	TCGA;ICGC;COSMIC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	Q9BPU6	DPYSL5	P49841	GSK3B	S534	D527N	527	Missense	distal	-7	no	7.805	7.808	EPSD	TCGA;ICGC;COSMIC	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	Q96F46	IL17RA	P49841	GSK3B	S561	G555V	555	Missense	distal	-6	no	6.951	6.867	EPSD	TCGA;ICGC;COSMIC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	Q96F46	IL17RA	P49841	GSK3B	T780	P778S	778	Missense	proximal	-2	no	9.209	8.953	PhosphoSitePlus	TCGA;ICGC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	Q96F46	IL17RA	P49841	GSK3B	S801	S798P	798	Missense	distal	-3	no	7.580	7.464	EPSD	TCGA;ICGC;COSMIC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	Q13485	SMAD4	P49841	GSK3B	T9	S12R	12	Missense	distal	3	no	6.597	6.226	EPSD	TCGA;ICGC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	Q13485	SMAD4	P49841	GSK3B	S138	Y133N	133	Missense	distal	-5	no	6.678	5.733	EPSD	TCGA;ICGC;COSMIC	6.007	Loss
CMGC_GSK_GSK3B_ST	Q13485	SMAD4	P49841	GSK3B	S138	H132Y	132	Missense	distal	-6	no	6.678	6.625	EPSD	TCGA;ICGC;COSMIC;GDSC;CCLE	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	Q13485	SMAD4	P49841	GSK3B	S138	E134K	134	Missense	distal	-4	no	6.678	6.410	EPSD	TCGA;ICGC;COSMIC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	Q13485	SMAD4	P49841	GSK3B	S138	V137A	137	Missense	proximal	-1	no	6.678	6.475	EPSD	TCGA;ICGC;COSMIC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	Q13485	SMAD4	P49841	GSK3B	S138	H132Q	132	Missense	distal	-6	no	6.678	6.707	EPSD	TCGA;ICGC;COSMIC;CCLE	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	Q13485	SMAD4	P49841	GSK3B	T273	P275T	275	Missense	proximal	2	no	7.721	7.404	PhosphoSitePlus;EPSD	TCGA;ICGC;COSMIC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	Q13485	SMAD4	P49841	GSK3B	T277	P275T	275	Missense	proximal	-2	no	7.392	7.163	EPSD	TCGA;ICGC;COSMIC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	P01112	HRAS	P49841	GSK3B	T35	D33N	33	Missense	proximal	-2	no	6.429	6.215	EPSD	TCGA;ICGC;COSMIC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	P01112	HRAS	P49841	GSK3B	T35	E31K	31	Missense	distal	-4	no	6.429	6.161	EPSD	TCGA;ICGC;COSMIC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	P01112	HRAS	P49841	GSK3B	T144	K147N	147	Missense	distal	3	no	8.137	8.311	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	P01112	HRAS	P49841	GSK3B	T144	E143K	143	Missense	proximal	-1	no	8.137	8.203	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	P17661	DES	P49841	GSK3B	S42	K43E	43	Missense	proximal	1	no	8.717	8.429	EPSD	TCGA;ICGC;COSMIC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	P17661	DES	P49841	GSK3B	S42	G41V	41	Missense	proximal	-1	no	8.717	8.758	EPSD	TCGA;ICGC;COSMIC	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	P17661	DES	P49841	GSK3B	S46	K43E	43	Missense	distal	-3	no	6.402	6.391	EPSD	TCGA;ICGC;COSMIC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	P17661	DES	P49841	GSK3B	S46	G41V	41	Missense	distal	-5	no	6.402	6.515	EPSD	TCGA;ICGC;COSMIC	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	P17661	DES	P49841	GSK3B	S68	G61V	61	Missense	distal	-7	no	7.718	7.742	EPSD	TCGA;ICGC;COSMIC	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	P17661	DES	P49841	GSK3B	S72	R78H	78	Missense	distal	6	no	8.505	8.500	EPSD	TCGA;ICGC;COSMIC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	P17661	DES	P49841	GSK3B	T77	R78H	78	Missense	proximal	1	no	6.933	5.552	EPSD	TCGA;ICGC;COSMIC	6.007	Loss
CMGC_GSK_GSK3B_ST	P17661	DES	P49841	GSK3B	S432	N427S	427	Missense	distal	-5	no	7.534	7.826	EPSD	TCGA;ICGC;COSMIC	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	P17661	DES	P49841	GSK3B	T453	E452K	452	Missense	proximal	-1	no	5.968	6.035	EPSD	TCGA;ICGC;COSMIC	6.007	Gain
CMGC_GSK_GSK3B_ST	P35222	CTNNB1	P49841	GSK3B	S29	G34R	34	Missense	distal	5	no	6.757	7.031	EPSD	TCGA;COSMIC	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	P35222	CTNNB1	P49841	GSK3B	S29	G34V	34	Missense	distal	5	no	6.757	6.213	EPSD	TCGA;COSMIC;CCLE	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	P35222	CTNNB1	P49841	GSK3B	S29	G34E	34	Missense	distal	5	no	6.757	7.023	EPSD	TCGA;COSMIC;GDSC;CCLE	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	P35222	CTNNB1	P49841	GSK3B	S29	S33F	33	Missense	distal	4	no	6.757	3.142	EPSD	TCGA;COSMIC;GDSC;CCLE	6.007	Loss
CMGC_GSK_GSK3B_ST	P35222	CTNNB1	P49841	GSK3B	S29	D32H	32	Missense	distal	3	no	6.757	6.633	EPSD	TCGA;COSMIC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	P35222	CTNNB1	P49841	GSK3B	S29	D32G	32	Missense	distal	3	no	6.757	6.706	EPSD	TCGA;COSMIC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	P35222	CTNNB1	P49841	GSK3B	S29	S33A	33	Missense	distal	4	no	6.757	4.345	EPSD	TCGA;COSMIC	6.007	Loss
CMGC_GSK_GSK3B_ST	P35222	CTNNB1	P49841	GSK3B	S29	S33Y	33	Missense	distal	4	no	6.757	3.244	EPSD	TCGA;COSMIC;GDSC;CCLE	6.007	Loss
CMGC_GSK_GSK3B_ST	P35222	CTNNB1	P49841	GSK3B	S29	D32V	32	Missense	distal	3	no	6.757	6.454	EPSD	TCGA;COSMIC;CCLE	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	P35222	CTNNB1	P49841	GSK3B	S29	S33P	33	Missense	distal	4	no	6.757	3.786	EPSD	TCGA;COSMIC;CCLE	6.007	Loss
CMGC_GSK_GSK3B_ST	P35222	CTNNB1	P49841	GSK3B	S29	H36P	36	Missense	distal	7	no	6.757	6.068	EPSD	TCGA;COSMIC;CCLE	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	P35222	CTNNB1	P49841	GSK3B	S29	D32Y	32	Missense	distal	3	no	6.757	6.239	EPSD	TCGA;COSMIC;CCLE	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	P35222	CTNNB1	P49841	GSK3B	S29	S33C	33	Missense	distal	4	no	6.757	0.624	EPSD	TCGA;COSMIC;GDSC;CCLE	6.007	Loss
CMGC_GSK_GSK3B_ST	P35222	CTNNB1	P49841	GSK3B	S29	D32N	32	Missense	distal	3	no	6.757	6.710	EPSD	TCGA;COSMIC;CCLE	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	P35222	CTNNB1	P49841	GSK3B	S29	S33T	33	Missense	distal	4	no	6.757	5.888	EPSD	TCGA;COSMIC	6.007	Loss
CMGC_GSK_GSK3B_ST	P35222	CTNNB1	P49841	GSK3B	S29	D32A	32	Missense	distal	3	no	6.757	6.325	EPSD	TCGA;COSMIC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	P35222	CTNNB1	P49841	GSK3B	S33	G34R	34	Missense	proximal	1	no	7.768	8.642	EPSD;PhosphoSitePlus	TCGA;COSMIC	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	P35222	CTNNB1	P49841	GSK3B	S33	G34V	34	Missense	proximal	1	no	7.768	7.971	EPSD;PhosphoSitePlus	TCGA;COSMIC;CCLE	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	P35222	CTNNB1	P49841	GSK3B	S33	G34E	34	Missense	proximal	1	no	7.768	7.128	EPSD;PhosphoSitePlus	TCGA;COSMIC;GDSC;CCLE	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	P35222	CTNNB1	P49841	GSK3B	S33	S37C	37	Missense	distal	4	no	7.768	1.635	EPSD;PhosphoSitePlus	TCGA;COSMIC;GDSC;CCLE	6.007	Loss
CMGC_GSK_GSK3B_ST	P35222	CTNNB1	P49841	GSK3B	S33	S37F	37	Missense	distal	4	no	7.768	4.153	EPSD;PhosphoSitePlus	TCGA;COSMIC;GDSC;CCLE	6.007	Loss
CMGC_GSK_GSK3B_ST	P35222	CTNNB1	P49841	GSK3B	S33	S33F	33	Missense	central	0	yes	7.768	0.000	EPSD;PhosphoSitePlus	TCGA;COSMIC;GDSC;CCLE	6.007	Loss
CMGC_GSK_GSK3B_ST	P35222	CTNNB1	P49841	GSK3B	S33	D32H	32	Missense	proximal	-1	no	7.768	7.777	EPSD;PhosphoSitePlus	TCGA;COSMIC	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	P35222	CTNNB1	P49841	GSK3B	S33	D32G	32	Missense	proximal	-1	no	7.768	7.835	EPSD;PhosphoSitePlus	TCGA;COSMIC	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	P35222	CTNNB1	P49841	GSK3B	S33	S33A	33	Missense	central	0	yes	7.768	0.000	EPSD;PhosphoSitePlus	TCGA;COSMIC	6.007	Loss
CMGC_GSK_GSK3B_ST	P35222	CTNNB1	P49841	GSK3B	S33	S33Y	33	Missense	central	0	yes	7.768	0.000	EPSD;PhosphoSitePlus	TCGA;COSMIC;GDSC;CCLE	6.007	Loss
CMGC_GSK_GSK3B_ST	P35222	CTNNB1	P49841	GSK3B	S33	D32V	32	Missense	proximal	-1	no	7.768	7.876	EPSD;PhosphoSitePlus	TCGA;COSMIC;CCLE	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	P35222	CTNNB1	P49841	GSK3B	S33	S33P	33	Missense	central	0	yes	7.768	0.000	EPSD;PhosphoSitePlus	TCGA;COSMIC;CCLE	6.007	Loss
CMGC_GSK_GSK3B_ST	P35222	CTNNB1	P49841	GSK3B	S33	H36P	36	Missense	distal	3	no	7.768	7.814	EPSD;PhosphoSitePlus	TCGA;COSMIC;CCLE	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	P35222	CTNNB1	P49841	GSK3B	S33	D32Y	32	Missense	proximal	-1	no	7.768	7.688	EPSD;PhosphoSitePlus	TCGA;COSMIC;CCLE	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	P35222	CTNNB1	P49841	GSK3B	S33	I35S	35	Missense	proximal	2	no	7.768	7.707	EPSD;PhosphoSitePlus	TCGA;COSMIC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	P35222	CTNNB1	P49841	GSK3B	S33	S37Y	37	Missense	distal	4	no	7.768	4.255	EPSD;PhosphoSitePlus	TCGA;COSMIC	6.007	Loss
CMGC_GSK_GSK3B_ST	P35222	CTNNB1	P49841	GSK3B	S33	S33C	33	Missense	central	0	yes	7.768	0.000	EPSD;PhosphoSitePlus	TCGA;COSMIC;GDSC;CCLE	6.007	Loss
CMGC_GSK_GSK3B_ST	P35222	CTNNB1	P49841	GSK3B	S33	S37A	37	Missense	distal	4	no	7.768	5.356	EPSD;PhosphoSitePlus	TCGA;COSMIC;GDSC;CCLE	6.007	Loss
CMGC_GSK_GSK3B_ST	P35222	CTNNB1	P49841	GSK3B	S33	D32N	32	Missense	proximal	-1	no	7.768	7.890	EPSD;PhosphoSitePlus	TCGA;COSMIC;CCLE	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	P35222	CTNNB1	P49841	GSK3B	S33	S37P	37	Missense	distal	4	no	7.768	4.797	EPSD;PhosphoSitePlus	TCGA;COSMIC;GDSC;CCLE	6.007	Loss
CMGC_GSK_GSK3B_ST	P35222	CTNNB1	P49841	GSK3B	S33	D32A	32	Missense	proximal	-1	no	7.768	7.673	EPSD;PhosphoSitePlus	TCGA;COSMIC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	P35222	CTNNB1	P49841	GSK3B	S37	G34R	34	Missense	distal	-3	no	7.839	8.012	PhosphoSitePlus;EPSD	TCGA;COSMIC	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	P35222	CTNNB1	P49841	GSK3B	S37	G34V	34	Missense	distal	-3	no	7.839	8.010	PhosphoSitePlus;EPSD	TCGA;COSMIC;CCLE	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	P35222	CTNNB1	P49841	GSK3B	S37	T41A	41	Missense	distal	4	no	7.839	6.296	PhosphoSitePlus;EPSD	TCGA;COSMIC;GDSC;CCLE	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	P35222	CTNNB1	P49841	GSK3B	S37	G34E	34	Missense	distal	-3	no	7.839	7.856	PhosphoSitePlus;EPSD	TCGA;COSMIC;GDSC;CCLE	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	P35222	CTNNB1	P49841	GSK3B	S37	S37C	37	Missense	central	0	yes	7.839	0.000	PhosphoSitePlus;EPSD	TCGA;COSMIC;GDSC;CCLE	6.007	Loss
CMGC_GSK_GSK3B_ST	P35222	CTNNB1	P49841	GSK3B	S37	S37F	37	Missense	central	0	yes	7.839	0.000	PhosphoSitePlus;EPSD	TCGA;COSMIC;GDSC;CCLE	6.007	Loss
CMGC_GSK_GSK3B_ST	P35222	CTNNB1	P49841	GSK3B	S37	S33F	33	Missense	distal	-4	no	7.839	6.685	PhosphoSitePlus;EPSD	TCGA;COSMIC;GDSC;CCLE	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	P35222	CTNNB1	P49841	GSK3B	S37	D32H	32	Missense	distal	-5	no	7.839	7.733	PhosphoSitePlus;EPSD	TCGA;COSMIC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	P35222	CTNNB1	P49841	GSK3B	S37	D32G	32	Missense	distal	-5	no	7.839	8.032	PhosphoSitePlus;EPSD	TCGA;COSMIC	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	P35222	CTNNB1	P49841	GSK3B	S37	T41I	41	Missense	distal	4	no	7.839	5.386	PhosphoSitePlus;EPSD	TCGA;COSMIC	6.007	Loss
CMGC_GSK_GSK3B_ST	P35222	CTNNB1	P49841	GSK3B	S37	S33A	33	Missense	distal	-4	no	7.839	6.679	PhosphoSitePlus;EPSD	TCGA;COSMIC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	P35222	CTNNB1	P49841	GSK3B	S37	S33Y	33	Missense	distal	-4	no	7.839	7.038	PhosphoSitePlus;EPSD	TCGA;COSMIC;GDSC;CCLE	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	P35222	CTNNB1	P49841	GSK3B	S37	D32V	32	Missense	distal	-5	no	7.839	8.146	PhosphoSitePlus;EPSD	TCGA;COSMIC;CCLE	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	P35222	CTNNB1	P49841	GSK3B	S37	S33P	33	Missense	distal	-4	no	7.839	7.275	PhosphoSitePlus;EPSD	TCGA;COSMIC;CCLE	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	P35222	CTNNB1	P49841	GSK3B	S37	H36P	36	Missense	proximal	-1	no	7.839	7.946	PhosphoSitePlus;EPSD	TCGA;COSMIC;CCLE	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	P35222	CTNNB1	P49841	GSK3B	S37	D32Y	32	Missense	distal	-5	no	7.839	8.219	PhosphoSitePlus;EPSD	TCGA;COSMIC;CCLE	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	P35222	CTNNB1	P49841	GSK3B	S37	I35S	35	Missense	proximal	-2	no	7.839	7.849	PhosphoSitePlus;EPSD	TCGA;COSMIC	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	P35222	CTNNB1	P49841	GSK3B	S37	S37Y	37	Missense	central	0	yes	7.839	0.000	PhosphoSitePlus;EPSD	TCGA;COSMIC	6.007	Loss
CMGC_GSK_GSK3B_ST	P35222	CTNNB1	P49841	GSK3B	S37	S33C	33	Missense	distal	-4	no	7.839	5.724	PhosphoSitePlus;EPSD	TCGA;COSMIC;GDSC;CCLE	6.007	Loss
CMGC_GSK_GSK3B_ST	P35222	CTNNB1	P49841	GSK3B	S37	S37A	37	Missense	central	0	yes	7.839	0.000	PhosphoSitePlus;EPSD	TCGA;COSMIC;GDSC;CCLE	6.007	Loss
CMGC_GSK_GSK3B_ST	P35222	CTNNB1	P49841	GSK3B	S37	D32N	32	Missense	distal	-5	no	7.839	7.274	PhosphoSitePlus;EPSD	TCGA;COSMIC;CCLE	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	P35222	CTNNB1	P49841	GSK3B	S37	S33T	33	Missense	distal	-4	no	7.839	7.503	PhosphoSitePlus;EPSD	TCGA;COSMIC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	P35222	CTNNB1	P49841	GSK3B	S37	T41N	41	Missense	distal	4	no	7.839	5.097	PhosphoSitePlus;EPSD	TCGA;COSMIC	6.007	Loss
CMGC_GSK_GSK3B_ST	P35222	CTNNB1	P49841	GSK3B	S37	S37P	37	Missense	central	0	yes	7.839	0.000	PhosphoSitePlus;EPSD	TCGA;COSMIC;GDSC;CCLE	6.007	Loss
CMGC_GSK_GSK3B_ST	P35222	CTNNB1	P49841	GSK3B	S37	D32A	32	Missense	distal	-5	no	7.839	7.844	PhosphoSitePlus;EPSD	TCGA;COSMIC	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	P35222	CTNNB1	P49841	GSK3B	T41	S45F	45	Missense	distal	4	no	7.890	4.276	EPSD;PhosphoSitePlus	TCGA;COSMIC;GDSC;CCLE	6.007	Loss
CMGC_GSK_GSK3B_ST	P35222	CTNNB1	P49841	GSK3B	T41	G34R	34	Missense	distal	-7	no	7.890	7.911	EPSD;PhosphoSitePlus	TCGA;COSMIC	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	P35222	CTNNB1	P49841	GSK3B	T41	S45P	45	Missense	distal	4	no	7.890	4.919	EPSD;PhosphoSitePlus	TCGA;COSMIC;CCLE	6.007	Loss
CMGC_GSK_GSK3B_ST	P35222	CTNNB1	P49841	GSK3B	T41	G34V	34	Missense	distal	-7	no	7.890	7.914	EPSD;PhosphoSitePlus	TCGA;COSMIC;CCLE	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	P35222	CTNNB1	P49841	GSK3B	T41	T41A	41	Missense	central	0	yes	7.890	0.000	EPSD;PhosphoSitePlus	TCGA;COSMIC;GDSC;CCLE	6.007	Loss
CMGC_GSK_GSK3B_ST	P35222	CTNNB1	P49841	GSK3B	T41	G34E	34	Missense	distal	-7	no	7.890	7.925	EPSD;PhosphoSitePlus	TCGA;COSMIC;GDSC;CCLE	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	P35222	CTNNB1	P49841	GSK3B	T41	S37C	37	Missense	distal	-4	no	7.890	5.776	EPSD;PhosphoSitePlus	TCGA;COSMIC;GDSC;CCLE	6.007	Loss
CMGC_GSK_GSK3B_ST	P35222	CTNNB1	P49841	GSK3B	T41	S37F	37	Missense	distal	-4	no	7.890	6.736	EPSD;PhosphoSitePlus	TCGA;COSMIC;GDSC;CCLE	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	P35222	CTNNB1	P49841	GSK3B	T41	T41I	41	Missense	central	0	yes	7.890	0.000	EPSD;PhosphoSitePlus	TCGA;COSMIC	6.007	Loss
CMGC_GSK_GSK3B_ST	P35222	CTNNB1	P49841	GSK3B	T41	S45Y	45	Missense	distal	4	no	7.890	4.377	EPSD;PhosphoSitePlus	TCGA;COSMIC	6.007	Loss
CMGC_GSK_GSK3B_ST	P35222	CTNNB1	P49841	GSK3B	T41	H36P	36	Missense	distal	-5	no	7.890	7.567	EPSD;PhosphoSitePlus	TCGA;COSMIC;CCLE	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	P35222	CTNNB1	P49841	GSK3B	T41	I35S	35	Missense	distal	-6	no	7.890	7.953	EPSD;PhosphoSitePlus	TCGA;COSMIC	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	P35222	CTNNB1	P49841	GSK3B	T41	S37Y	37	Missense	distal	-4	no	7.890	7.090	EPSD;PhosphoSitePlus	TCGA;COSMIC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	P35222	CTNNB1	P49841	GSK3B	T41	S37A	37	Missense	distal	-4	no	7.890	6.731	EPSD;PhosphoSitePlus	TCGA;COSMIC;GDSC;CCLE	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	P35222	CTNNB1	P49841	GSK3B	T41	T41N	41	Missense	central	0	yes	7.890	0.000	EPSD;PhosphoSitePlus	TCGA;COSMIC	6.007	Loss
CMGC_GSK_GSK3B_ST	P35222	CTNNB1	P49841	GSK3B	T41	S45C	45	Missense	distal	4	no	7.890	1.758	EPSD;PhosphoSitePlus	TCGA;COSMIC;GDSC;CCLE	6.007	Loss
CMGC_GSK_GSK3B_ST	P35222	CTNNB1	P49841	GSK3B	T41	S37P	37	Missense	distal	-4	no	7.890	7.327	EPSD;PhosphoSitePlus	TCGA;COSMIC;GDSC;CCLE	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	P35222	CTNNB1	P49841	GSK3B	S45	S45F	45	Missense	central	0	yes	6.277	0.000	EPSD	TCGA;COSMIC;GDSC;CCLE	6.007	Loss
CMGC_GSK_GSK3B_ST	P35222	CTNNB1	P49841	GSK3B	S45	S45P	45	Missense	central	0	yes	6.277	0.000	EPSD	TCGA;COSMIC;CCLE	6.007	Loss
CMGC_GSK_GSK3B_ST	P35222	CTNNB1	P49841	GSK3B	S45	T41A	41	Missense	distal	-4	no	6.277	5.453	EPSD	TCGA;COSMIC;GDSC;CCLE	6.007	Loss
CMGC_GSK_GSK3B_ST	P35222	CTNNB1	P49841	GSK3B	S45	T41I	41	Missense	distal	-4	no	6.277	4.130	EPSD	TCGA;COSMIC	6.007	Loss
CMGC_GSK_GSK3B_ST	P35222	CTNNB1	P49841	GSK3B	S45	S45Y	45	Missense	central	0	yes	6.277	0.000	EPSD	TCGA;COSMIC	6.007	Loss
CMGC_GSK_GSK3B_ST	P35222	CTNNB1	P49841	GSK3B	S45	T41N	41	Missense	distal	-4	no	6.277	5.315	EPSD	TCGA;COSMIC	6.007	Loss
CMGC_GSK_GSK3B_ST	P35222	CTNNB1	P49841	GSK3B	S45	S45C	45	Missense	central	0	yes	6.277	0.000	EPSD	TCGA;COSMIC;GDSC;CCLE	6.007	Loss
CMGC_GSK_GSK3B_ST	P35222	CTNNB1	P49841	GSK3B	S191	A197S	197	Missense	distal	6	no	6.205	6.207	EPSD	TCGA;COSMIC	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	P35222	CTNNB1	P49841	GSK3B	S191	R185G	185	Missense	distal	-6	no	6.205	6.279	EPSD	TCGA;COSMIC	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	P35222	CTNNB1	P49841	GSK3B	T547	V541A	541	Missense	distal	-6	no	5.958	6.036	EPSD	TCGA;COSMIC	6.007	Gain
CMGC_GSK_GSK3B_ST	P35222	CTNNB1	P49841	GSK3B	S605	P606L	606	Missense	proximal	1	no	6.798	3.938	EPSD	TCGA;COSMIC	6.007	Loss
CMGC_GSK_GSK3B_ST	P35222	CTNNB1	P49841	GSK3B	S681	F683Y	683	Missense	proximal	2	no	7.674	7.786	EPSD	TCGA;COSMIC	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	P35222	CTNNB1	P49841	GSK3B	S681	S681F	681	Missense	central	0	yes	7.674	0.000	EPSD	TCGA	6.007	Loss
CMGC_GSK_GSK3B_ST	P35222	CTNNB1	P49841	GSK3B	S681	P687S	687	Missense	distal	6	no	7.674	7.672	EPSD	TCGA;COSMIC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	P35222	CTNNB1	P49841	GSK3B	S681	P687L	687	Missense	distal	6	no	7.674	7.667	EPSD	TCGA;COSMIC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	P21796	VDAC1	P49841	GSK3B	T42	S46L	46	Missense	distal	4	no	7.594	4.876	EPSD	TCGA;ICGC;COSMIC	6.007	Loss
CMGC_GSK_GSK3B_ST	P21796	VDAC1	P49841	GSK3B	S104	S104L	104	Missense	central	0	yes	6.317	0.000	EPSD	TCGA;ICGC;COSMIC	6.007	Loss
CMGC_GSK_GSK3B_ST	O60346	PHLPP1	P49841	GSK3B	S1359	R1354C	1354	Missense	distal	-5	no	8.796	8.618	EPSD;PhosphoSitePlus	TCGA;COSMIC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	O60346	PHLPP1	P49841	GSK3B	T1363	F1368L	1368	Missense	distal	5	no	9.412	9.752	EPSD;PhosphoSitePlus	TCGA;COSMIC	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	O43623	SNAI2	P49841	GSK3B	S54	G51E	51	Missense	distal	-3	no	8.846	8.863	EPSD	TCGA;ICGC;COSMIC	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	O43623	SNAI2	P49841	GSK3B	S54	A52E	52	Missense	proximal	-2	no	8.846	9.078	EPSD	TCGA;ICGC;COSMIC	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	O43623	SNAI2	P49841	GSK3B	S92	K97M	97	Missense	distal	5	no	7.260	7.680	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	O43623	SNAI2	P49841	GSK3B	S92	D98Y	98	Missense	distal	6	no	7.260	7.261	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	O43623	SNAI2	P49841	GSK3B	S96	K97M	97	Missense	proximal	1	no	7.461	7.421	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	O43623	SNAI2	P49841	GSK3B	S96	D98Y	98	Missense	proximal	2	no	7.461	7.137	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	O43623	SNAI2	P49841	GSK3B	S100	K97M	97	Missense	distal	-3	no	7.492	7.440	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	O43623	SNAI2	P49841	GSK3B	S100	D98Y	98	Missense	proximal	-2	no	7.492	7.189	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	O43623	SNAI2	P49841	GSK3B	S104	E110K	110	Missense	distal	6	no	9.411	9.412	PhosphoSitePlus;EPSD	TCGA;ICGC;COSMIC	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	O43623	SNAI2	P49841	GSK3B	S104	E110V	110	Missense	distal	6	no	9.411	9.407	PhosphoSitePlus;EPSD	TCGA;ICGC;COSMIC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	O43623	SNAI2	P49841	GSK3B	S104	D98Y	98	Missense	distal	-6	no	9.411	9.350	PhosphoSitePlus;EPSD	TCGA;ICGC;COSMIC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	O43623	SNAI2	P49841	GSK3B	S247	F250L	250	Missense	distal	3	no	6.713	6.623	EPSD	TCGA;ICGC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	O43623	SNAI2	P49841	GSK3B	S247	S247F	247	Missense	central	0	yes	6.713	0.000	EPSD	TCGA	6.007	Loss
CMGC_GSK_GSK3B_ST	O43623	SNAI2	P49841	GSK3B	S247	T249P	249	Missense	proximal	2	no	6.713	7.031	EPSD	TCGA;ICGC;COSMIC	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	Q9BXF6	RAB11FIP5	P49841	GSK3B	T165	Q167H	167	Missense	proximal	2	no	7.251	6.703	EPSD	TCGA;ICGC;COSMIC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	Q9BXF6	RAB11FIP5	P49841	GSK3B	T165	R170C	170	Missense	distal	5	no	7.251	5.695	EPSD	TCGA;ICGC;COSMIC	6.007	Loss
CMGC_GSK_GSK3B_ST	Q9BXF6	RAB11FIP5	P49841	GSK3B	S188	R194G	194	Missense	distal	6	no	6.716	6.718	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	Q9BXF6	RAB11FIP5	P49841	GSK3B	S188	P189L	189	Missense	proximal	1	no	6.716	3.856	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	6.007	Loss
CMGC_GSK_GSK3B_ST	Q9BXF6	RAB11FIP5	P49841	GSK3B	S244	R241P	241	Missense	distal	-3	no	6.773	6.487	EPSD	TCGA;ICGC;COSMIC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	Q9BXF6	RAB11FIP5	P49841	GSK3B	S244	R241H	241	Missense	distal	-3	no	6.773	6.716	EPSD	TCGA;ICGC;COSMIC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	Q9BXF6	RAB11FIP5	P49841	GSK3B	T246	R241P	241	Missense	distal	-5	no	6.074	5.220	EPSD	TCGA;ICGC;COSMIC	6.007	Loss
CMGC_GSK_GSK3B_ST	Q9BXF6	RAB11FIP5	P49841	GSK3B	T246	R241H	241	Missense	distal	-5	no	6.074	5.543	EPSD	TCGA;ICGC;COSMIC	6.007	Loss
CMGC_GSK_GSK3B_ST	Q9BXF6	RAB11FIP5	P49841	GSK3B	S256	S259F	259	Missense	distal	3	no	6.295	6.085	EPSD	TCGA;ICGC;COSMIC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	Q9BXF6	RAB11FIP5	P49841	GSK3B	S260	S259F	259	Missense	proximal	-1	no	7.907	7.777	EPSD	TCGA;ICGC;COSMIC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	Q9BXF6	RAB11FIP5	P49841	GSK3B	T276	P270H	270	Missense	distal	-6	no	6.143	6.088	PhosphoSitePlus;EPSD	TCGA;ICGC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	Q9BXF6	RAB11FIP5	P49841	GSK3B	T276	L274V	274	Missense	proximal	-2	no	6.143	6.185	PhosphoSitePlus;EPSD	TCGA;ICGC;COSMIC	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	Q9BXF6	RAB11FIP5	P49841	GSK3B	T276	E273K	273	Missense	distal	-3	no	6.143	6.153	PhosphoSitePlus;EPSD	TCGA;ICGC;COSMIC	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	Q9BXF6	RAB11FIP5	P49841	GSK3B	T276	S280N	280	Missense	distal	4	no	6.143	2.533	PhosphoSitePlus;EPSD	TCGA;ICGC	6.007	Loss
CMGC_GSK_GSK3B_ST	Q9BXF6	RAB11FIP5	P49841	GSK3B	S278	L274V	274	Missense	distal	-4	no	8.421	8.537	EPSD	TCGA;ICGC;COSMIC	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	Q9BXF6	RAB11FIP5	P49841	GSK3B	S278	E273K	273	Missense	distal	-5	no	8.421	8.190	EPSD	TCGA;ICGC;COSMIC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	Q9BXF6	RAB11FIP5	P49841	GSK3B	S278	S280N	280	Missense	proximal	2	no	8.421	7.889	EPSD	TCGA;ICGC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	Q9BXF6	RAB11FIP5	P49841	GSK3B	S282	S280N	280	Missense	proximal	-2	no	6.182	5.953	EPSD	TCGA;ICGC	6.007	Loss
CMGC_GSK_GSK3B_ST	Q9BXF6	RAB11FIP5	P49841	GSK3B	S283	S280N	280	Missense	distal	-3	no	6.743	6.648	EPSD	TCGA;ICGC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	Q9BXF6	RAB11FIP5	P49841	GSK3B	S293	P297S	297	Missense	distal	4	no	3.479	6.450	EPSD	TCGA;ICGC;COSMIC	6.007	Gain
CMGC_GSK_GSK3B_ST	Q9BXF6	RAB11FIP5	P49841	GSK3B	S361	S361L	361	Missense	central	0	yes	8.012	0.000	EPSD	TCGA;ICGC;COSMIC	6.007	Loss
CMGC_GSK_GSK3B_ST	Q9BXF6	RAB11FIP5	P49841	GSK3B	S361	R355H	355	Missense	distal	-6	no	8.012	8.036	EPSD	TCGA;ICGC;COSMIC;CCLE	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	Q9BXF6	RAB11FIP5	P49841	GSK3B	S365	Q369E	369	Missense	distal	4	no	5.916	7.459	EPSD	TCGA;ICGC;COSMIC	6.007	Gain
CMGC_GSK_GSK3B_ST	Q9BXF6	RAB11FIP5	P49841	GSK3B	S373	R374W	374	Missense	proximal	1	no	6.129	6.347	EPSD	TCGA;ICGC;COSMIC;CCLE	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	Q9BXF6	RAB11FIP5	P49841	GSK3B	S373	S376T	376	Missense	distal	3	no	6.129	6.097	EPSD	TCGA;ICGC;COSMIC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	Q9BXF6	RAB11FIP5	P49841	GSK3B	S373	Q369E	369	Missense	distal	-4	no	6.129	6.362	EPSD	TCGA;ICGC;COSMIC	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	Q9BXF6	RAB11FIP5	P49841	GSK3B	S373	P380T	380	Missense	distal	7	no	6.129	6.134	EPSD	TCGA;ICGC	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	Q9BXF6	RAB11FIP5	P49841	GSK3B	S391	S391G	391	Missense	central	0	yes	7.035	0.000	EPSD	TCGA;ICGC;COSMIC	6.007	Loss
CMGC_GSK_GSK3B_ST	Q9BXF6	RAB11FIP5	P49841	GSK3B	S391	R392C	392	Missense	proximal	1	no	7.035	5.032	EPSD	TCGA;ICGC;COSMIC	6.007	Loss
CMGC_GSK_GSK3B_ST	Q9BXF6	RAB11FIP5	P49841	GSK3B	S494	A493T	493	Missense	proximal	-1	no	6.041	6.120	EPSD	TCGA	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	Q9BXF6	RAB11FIP5	P49841	GSK3B	S494	G492V	492	Missense	proximal	-2	no	6.041	6.126	EPSD	TCGA;ICGC;COSMIC	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	Q9BXF6	RAB11FIP5	P49841	GSK3B	S494	P489S	489	Missense	distal	-5	no	6.041	6.197	EPSD	TCGA;ICGC;COSMIC	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	Q9BXF6	RAB11FIP5	P49841	GSK3B	S494	S500N	500	Missense	distal	6	no	6.041	6.034	EPSD	TCGA;ICGC;COSMIC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	Q9BXF6	RAB11FIP5	P49841	GSK3B	T519	D517G	517	Missense	proximal	-2	no	6.652	6.550	EPSD	TCGA;ICGC;COSMIC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	Q9BXF6	RAB11FIP5	P49841	GSK3B	S523	D517G	517	Missense	distal	-6	no	6.242	6.283	EPSD	TCGA;ICGC;COSMIC	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	Q9BXF6	RAB11FIP5	P49841	GSK3B	S523	L530F	530	Missense	distal	7	no	6.242	6.334	EPSD	TCGA;ICGC;COSMIC	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	Q9BXF6	RAB11FIP5	P49841	GSK3B	S523	V527M	527	Missense	distal	4	no	6.242	6.397	EPSD	TCGA;ICGC	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	Q9BXF6	RAB11FIP5	P49841	GSK3B	S538	A533T	533	Missense	distal	-5	no	7.258	7.270	EPSD	TCGA;ICGC;COSMIC	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	Q9BXF6	RAB11FIP5	P49841	GSK3B	S538	V535L	535	Missense	distal	-3	no	7.258	7.100	EPSD	TCGA;ICGC;COSMIC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	Q9BXF6	RAB11FIP5	P49841	GSK3B	S538	D540N	540	Missense	proximal	2	no	7.258	6.634	EPSD	TCGA;ICGC;COSMIC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	Q9BXF6	RAB11FIP5	P49841	GSK3B	S641	P648S	648	Missense	distal	7	no	6.131	6.194	EPSD	TCGA;ICGC;COSMIC	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	P08047	SP1	P49841	GSK3B	S42	T49A	49	Missense	distal	7	no	6.374	6.781	EPSD	TCGA;ICGC	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	P08047	SP1	P49841	GSK3B	T43	T49A	49	Missense	distal	6	no	6.239	6.235	EPSD	TCGA;ICGC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	P08047	SP1	P49841	GSK3B	S59	L61V	61	Missense	proximal	2	no	6.846	6.517	EPSD	TCGA;ICGC;COSMIC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	P08047	SP1	P49841	GSK3B	S59	S59F	59	Missense	central	0	yes	6.846	0.000	EPSD	TCGA;ICGC;COSMIC	6.007	Loss
CMGC_GSK_GSK3B_ST	P08047	SP1	P49841	GSK3B	S69	S69N	69	Missense	central	0	yes	9.099	0.000	EPSD	TCGA;ICGC;COSMIC	6.007	Loss
CMGC_GSK_GSK3B_ST	P08047	SP1	P49841	GSK3B	S69	C68R	68	Missense	proximal	-1	no	9.099	8.997	EPSD	TCGA;ICGC;COSMIC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	P08047	SP1	P49841	GSK3B	S69	P74S	74	Missense	distal	5	no	9.099	8.144	EPSD	TCGA;ICGC;COSMIC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	P08047	SP1	P49841	GSK3B	S73	S69N	69	Missense	distal	-4	no	7.500	6.202	EPSD	TCGA;ICGC;COSMIC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	P08047	SP1	P49841	GSK3B	S73	C68R	68	Missense	distal	-5	no	7.500	7.678	EPSD	TCGA;ICGC;COSMIC	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	P08047	SP1	P49841	GSK3B	S73	P74S	74	Missense	proximal	1	no	7.500	3.655	EPSD	TCGA;ICGC;COSMIC	6.007	Loss
CMGC_GSK_GSK3B_ST	P08047	SP1	P49841	GSK3B	S73	S78N	78	Missense	distal	5	no	7.500	7.179	EPSD	TCGA;ICGC;COSMIC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	P08047	SP1	P49841	GSK3B	S81	P74S	74	Missense	distal	-7	no	6.644	6.646	EPSD	TCGA;ICGC;COSMIC	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	P08047	SP1	P49841	GSK3B	S81	S78N	78	Missense	distal	-3	no	6.644	6.550	EPSD	TCGA;ICGC;COSMIC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	P08047	SP1	P49841	GSK3B	S588	D590E	590	Missense	proximal	2	no	7.559	7.380	EPSD	TCGA;ICGC;COSMIC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	P08047	SP1	P49841	GSK3B	S588	S588N	588	Missense	central	0	yes	7.559	0.000	EPSD	TCGA;ICGC;COSMIC	6.007	Loss
CMGC_GSK_GSK3B_ST	P08047	SP1	P49841	GSK3B	S698	R697K	697	Missense	proximal	-1	no	6.831	7.023	EPSD	TCGA;ICGC;COSMIC	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	P08047	SP1	P49841	GSK3B	S728	G731S	731	Missense	distal	3	no	6.055	6.011	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	P08047	SP1	P49841	GSK3B	S728	S728C	728	Missense	central	0	yes	6.055	0.000	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	6.007	Loss
CMGC_GSK_GSK3B_ST	P08047	SP1	P49841	GSK3B	S732	G736S	736	Missense	distal	4	no	2.966	6.209	PhosphoSitePlus;EPSD	TCGA;ICGC;COSMIC	6.007	Gain
CMGC_GSK_GSK3B_ST	P08047	SP1	P49841	GSK3B	S735	G731S	731	Missense	distal	-4	no	6.564	6.993	EPSD	TCGA;ICGC;COSMIC	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	P08047	SP1	P49841	GSK3B	S735	S728C	728	Missense	distal	-7	no	6.564	6.587	EPSD	TCGA;ICGC;COSMIC	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	P08047	SP1	P49841	GSK3B	S735	A742T	742	Missense	distal	7	no	6.564	6.158	EPSD	TCGA;ICGC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	P08047	SP1	P49841	GSK3B	S735	G736S	736	Missense	proximal	1	no	6.564	5.914	EPSD	TCGA;ICGC;COSMIC	6.007	Loss
CMGC_GSK_GSK3B_ST	P08047	SP1	P49841	GSK3B	T737	I744F	744	Missense	distal	7	no	6.983	6.725	EPSD	TCGA;ICGC;COSMIC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	P08047	SP1	P49841	GSK3B	T737	G731S	731	Missense	distal	-6	no	6.983	6.967	EPSD	TCGA;ICGC;COSMIC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	P08047	SP1	P49841	GSK3B	T737	A742T	742	Missense	distal	5	no	6.983	7.035	EPSD	TCGA;ICGC	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	P08047	SP1	P49841	GSK3B	T737	G736S	736	Missense	proximal	-1	no	6.983	6.976	EPSD	TCGA;ICGC;COSMIC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	P08047	SP1	P49841	GSK3B	T739	A742T	742	Missense	distal	3	no	7.178	7.483	EPSD	TCGA;ICGC	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	P08047	SP1	P49841	GSK3B	T739	G736S	736	Missense	distal	-3	no	7.178	7.182	EPSD	TCGA;ICGC;COSMIC	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	P08047	SP1	P49841	GSK3B	S741	I744F	744	Missense	distal	3	no	6.380	6.589	EPSD	TCGA;ICGC;COSMIC	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	P08047	SP1	P49841	GSK3B	S741	A742T	742	Missense	proximal	1	no	6.380	6.921	EPSD	TCGA;ICGC	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	P08047	SP1	P49841	GSK3B	S741	G736S	736	Missense	distal	-5	no	6.380	5.914	EPSD	TCGA;ICGC;COSMIC	6.007	Loss
CMGC_GSK_GSK3B_ST	P31749	AKT1	P49841	GSK3B	T92	R96W	96	Missense	distal	4	no	7.359	6.448	EPSD	TCGA;ICGC;COSMIC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	P31749	AKT1	P49841	GSK3B	T92	P93S	93	Missense	proximal	1	no	7.359	3.515	EPSD	TCGA;ICGC;COSMIC	6.007	Loss
CMGC_GSK_GSK3B_ST	P31749	AKT1	P49841	GSK3B	S122	E116K	116	Missense	distal	-6	no	7.127	7.126	EPSD	TCGA;ICGC;COSMIC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	P31749	AKT1	P49841	GSK3B	S122	R121W	121	Missense	proximal	-1	no	7.127	7.239	EPSD	TCGA;ICGC;COSMIC	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	P31749	AKT1	P49841	GSK3B	S124	R121W	121	Missense	distal	-3	no	6.748	6.678	EPSD	TCGA;ICGC;COSMIC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	P31749	AKT1	P49841	GSK3B	S124	A131T	131	Missense	distal	7	no	6.748	6.342	EPSD	TCGA;ICGC;COSMIC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	P31749	AKT1	P49841	GSK3B	T312	G311D	311	Missense	proximal	-1	no	6.116	6.049	EPSD	TCGA;ICGC;COSMIC;GDSC;CCLE	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	P31749	AKT1	P49841	GSK3B	S422	Y417C	417	Missense	distal	-5	no	7.966	7.833	EPSD	TCGA;ICGC;COSMIC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	P31749	AKT1	P49841	GSK3B	S422	P423T	423	Missense	proximal	1	no	7.966	4.775	EPSD	TCGA;ICGC	6.007	Loss
CMGC_GSK_GSK3B_ST	P31749	AKT1	P49841	GSK3B	S422	E418K	418	Missense	distal	-4	no	7.966	7.699	EPSD	TCGA;ICGC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	P31749	AKT1	P49841	GSK3B	S431	S431L	431	Missense	central	0	yes	6.988	0.000	EPSD	TCGA;ICGC;COSMIC	6.007	Loss
CMGC_GSK_GSK3B_ST	P31749	AKT1	P49841	GSK3B	T435	S431L	431	Missense	distal	-4	no	6.225	4.875	EPSD	TCGA;ICGC;COSMIC	6.007	Loss
CMGC_GSK_GSK3B_ST	P31749	AKT1	P49841	GSK3B	T450	I447V	447	Missense	distal	-3	no	6.970	7.024	EPSD	TCGA;ICGC;COSMIC	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	P31749	AKT1	P49841	GSK3B	S473	S475L	475	Missense	proximal	2	no	6.180	6.240	PhosphoSitePlus;EPSD	TCGA;ICGC;COSMIC	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	P04637	TP53	P49841	GSK3B	S33	P27S	27	Missense	distal	-6	no	10.252	10.231	EPSD	TCGA;ICGC;COSMIC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	P04637	TP53	P49841	GSK3B	S33	P27L	27	Missense	distal	-6	no	10.252	10.229	EPSD	TCGA;ICGC;COSMIC;GDSC;CCLE	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	P04637	TP53	P49841	GSK3B	S46	D48N	48	Missense	proximal	2	no	6.634	6.011	EPSD	TCGA;ICGC;COSMIC;GDSC;CCLE	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	P04637	TP53	P49841	GSK3B	T125	L130P	130	Missense	distal	5	no	5.187	6.467	EPSD	TCGA;ICGC;COSMIC	6.007	Gain
CMGC_GSK_GSK3B_ST	P04637	TP53	P49841	GSK3B	S127	K132N	132	Missense	distal	5	no	7.079	7.317	EPSD	TCGA;ICGC;COSMIC;GDSC;CCLE	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	P04637	TP53	P49841	GSK3B	S127	S121Y	121	Missense	distal	-6	no	7.079	6.993	EPSD	TCGA;ICGC;COSMIC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	P04637	TP53	P49841	GSK3B	S127	K132E	132	Missense	distal	5	no	7.079	7.946	EPSD	TCGA;ICGC;COSMIC;GDSC;CCLE	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	P04637	TP53	P49841	GSK3B	S127	Y126C	126	Missense	proximal	-1	no	7.079	7.183	EPSD	TCGA;ICGC;COSMIC;GDSC	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	P04637	TP53	P49841	GSK3B	S127	S127P	127	Missense	central	0	yes	7.079	0.000	EPSD	TCGA;ICGC;COSMIC;GDSC;CCLE	6.007	Loss
CMGC_GSK_GSK3B_ST	P04637	TP53	P49841	GSK3B	S127	Y126N	126	Missense	proximal	-1	no	7.079	7.281	EPSD	TCGA;ICGC;COSMIC	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	P04637	TP53	P49841	GSK3B	S127	L130V	130	Missense	distal	3	no	7.079	7.172	EPSD	TCGA;ICGC;COSMIC;GDSC;CCLE	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	P04637	TP53	P49841	GSK3B	S127	K132T	132	Missense	distal	5	no	7.079	7.615	EPSD	TCGA;ICGC;COSMIC;GDSC;CCLE	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	P04637	TP53	P49841	GSK3B	S127	S127Y	127	Missense	central	0	yes	7.079	0.000	EPSD	TCGA;ICGC;COSMIC	6.007	Loss
CMGC_GSK_GSK3B_ST	P04637	TP53	P49841	GSK3B	S127	S127F	127	Missense	central	0	yes	7.079	0.000	EPSD	TCGA;ICGC;COSMIC;CCLE	6.007	Loss
CMGC_GSK_GSK3B_ST	P04637	TP53	P49841	GSK3B	S127	M133R	133	Missense	distal	6	no	7.079	7.080	EPSD	TCGA;ICGC;COSMIC	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	P04637	TP53	P49841	GSK3B	S127	K132R	132	Missense	distal	5	no	7.079	7.954	EPSD	TCGA;ICGC;COSMIC;GDSC;CCLE	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	P04637	TP53	P49841	GSK3B	S127	F134L	134	Missense	distal	7	no	7.079	6.987	EPSD	TCGA;ICGC;COSMIC;CCLE	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	P04637	TP53	P49841	GSK3B	S127	Y126S	126	Missense	proximal	-1	no	7.079	7.219	EPSD	TCGA;ICGC;COSMIC	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	P04637	TP53	P49841	GSK3B	S127	L130P	130	Missense	distal	3	no	7.079	7.397	EPSD	TCGA;ICGC;COSMIC	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	P04637	TP53	P49841	GSK3B	S127	L130F	130	Missense	distal	3	no	7.079	7.169	EPSD	TCGA;ICGC;COSMIC;CCLE	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	P04637	TP53	P49841	GSK3B	S127	F134V	134	Missense	distal	7	no	7.079	7.427	EPSD	TCGA;ICGC;COSMIC	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	P04637	TP53	P49841	GSK3B	S127	T125M	125	Missense	proximal	-2	no	7.079	6.721	EPSD	TCGA;ICGC;COSMIC;GDSC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	P04637	TP53	P49841	GSK3B	S127	Y126D	126	Missense	proximal	-1	no	7.079	7.159	EPSD	TCGA;ICGC;COSMIC;GDSC	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	P04637	TP53	P49841	GSK3B	S127	K120E	120	Missense	distal	-7	no	7.079	7.090	EPSD	TCGA;ICGC;COSMIC	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	P04637	TP53	P49841	GSK3B	S127	N131S	131	Missense	distal	4	no	7.079	10.689	EPSD	TCGA;ICGC;COSMIC	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	P04637	TP53	P49841	GSK3B	S127	T125P	125	Missense	proximal	-2	no	7.079	7.308	EPSD	TCGA;ICGC;COSMIC;CCLE	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	P04637	TP53	P49841	GSK3B	S127	S127C	127	Missense	central	0	yes	7.079	0.000	EPSD	TCGA;ICGC;COSMIC;CCLE	6.007	Loss
CMGC_GSK_GSK3B_ST	P04637	TP53	P49841	GSK3B	S127	N131I	131	Missense	distal	4	no	7.079	7.368	EPSD	TCGA;ICGC;COSMIC	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	P04637	TP53	P49841	GSK3B	S127	Y126H	126	Missense	proximal	-1	no	7.079	7.168	EPSD	TCGA;ICGC;COSMIC;GDSC	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	P04637	TP53	P49841	GSK3B	S127	K132Q	132	Missense	distal	5	no	7.079	7.615	EPSD	TCGA;ICGC;COSMIC;GDSC;CCLE	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	P04637	TP53	P49841	GSK3B	S127	L130R	130	Missense	distal	3	no	7.079	7.009	EPSD	TCGA;ICGC;COSMIC;CCLE	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	P04637	TP53	P49841	GSK3B	T150	W146S	146	Missense	distal	-4	no	4.205	6.222	EPSD	TCGA;ICGC;COSMIC	6.007	Gain
CMGC_GSK_GSK3B_ST	P04637	TP53	P49841	GSK3B	T155	R156P	156	Missense	proximal	1	no	4.832	7.152	EPSD	TCGA;ICGC;COSMIC;GDSC;CCLE	6.007	Gain
CMGC_GSK_GSK3B_ST	P04637	TP53	P49841	GSK3B	S183	G187S	187	Missense	distal	4	no	5.252	8.495	EPSD	TCGA;ICGC;COSMIC	6.007	Gain
CMGC_GSK_GSK3B_ST	P04637	TP53	P49841	GSK3B	T211	V216E	216	Missense	distal	5	no	5.404	6.214	EPSD	TCGA;ICGC;COSMIC	6.007	Gain
CMGC_GSK_GSK3B_ST	P04637	TP53	P49841	GSK3B	S315	K320E	320	Missense	distal	5	no	5.875	6.742	EPSD	TCGA;ICGC;COSMIC	6.007	Gain
CMGC_GSK_GSK3B_ST	P04637	TP53	P49841	GSK3B	S362	A355T	355	Missense	distal	-7	no	7.606	7.610	EPSD	TCGA;ICGC;COSMIC	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	Q14896	MYBPC3	P49841	GSK3B	S133	G128R	128	Missense	distal	-5	no	9.246	9.478	EPSD;PhosphoSitePlus	TCGA	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	Q14896	MYBPC3	P49841	GSK3B	S171	S175L	175	Missense	distal	4	no	6.348	3.630	EPSD	TCGA;ICGC;COSMIC	6.007	Loss
CMGC_GSK_GSK3B_ST	Q14896	MYBPC3	P49841	GSK3B	S171	V178M	178	Missense	distal	7	no	6.348	6.291	EPSD	TCGA;ICGC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	Q14896	MYBPC3	P49841	GSK3B	S175	S175L	175	Missense	central	0	yes	6.453	0.000	EPSD	TCGA;ICGC;COSMIC	6.007	Loss
CMGC_GSK_GSK3B_ST	Q14896	MYBPC3	P49841	GSK3B	S175	V178M	178	Missense	distal	3	no	6.453	6.470	EPSD	TCGA;ICGC	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	Q14896	MYBPC3	P49841	GSK3B	S284	D285A	285	Missense	proximal	1	no	6.574	5.945	EPSD	TCGA;ICGC;COSMIC	6.007	Loss
CMGC_GSK_GSK3B_ST	Q14896	MYBPC3	P49841	GSK3B	S284	R282W	282	Missense	proximal	-2	no	6.574	6.780	EPSD	TCGA;ICGC;COSMIC	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	Q14896	MYBPC3	P49841	GSK3B	S284	E288D	288	Missense	distal	4	no	6.574	6.171	EPSD	TCGA;ICGC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	Q14896	MYBPC3	P49841	GSK3B	S286	L293M	293	Missense	distal	7	no	5.663	6.046	EPSD	TCGA;ICGC;COSMIC	6.007	Gain
CMGC_GSK_GSK3B_ST	Q14896	MYBPC3	P49841	GSK3B	T307	K301N	301	Missense	distal	-6	no	10.058	10.118	EPSD	TCGA;ICGC;COSMIC	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	Q14896	MYBPC3	P49841	GSK3B	T307	R306Q	306	Missense	proximal	-1	no	10.058	10.088	EPSD	TCGA;ICGC;COSMIC	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	Q14896	MYBPC3	P49841	GSK3B	T307	K301R	301	Missense	distal	-6	no	10.058	10.063	EPSD	TCGA;ICGC;COSMIC	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	Q14896	MYBPC3	P49841	GSK3B	T307	P308L	308	Missense	proximal	1	no	10.058	7.197	EPSD	TCGA;ICGC;COSMIC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	Q14896	MYBPC3	P49841	GSK3B	T307	E314V	314	Missense	distal	7	no	10.058	10.444	EPSD	TCGA;ICGC;COSMIC	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	Q14896	MYBPC3	P49841	GSK3B	S311	R306Q	306	Missense	distal	-5	no	6.760	6.205	EPSD	TCGA;ICGC;COSMIC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	Q14896	MYBPC3	P49841	GSK3B	S311	P308L	308	Missense	distal	-3	no	6.760	6.886	EPSD	TCGA;ICGC;COSMIC	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	Q14896	MYBPC3	P49841	GSK3B	S311	E314V	314	Missense	distal	3	no	6.760	6.571	EPSD	TCGA;ICGC;COSMIC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	Q14896	MYBPC3	P49841	GSK3B	T607	A612T	612	Missense	distal	5	no	7.615	7.667	EPSD	TCGA;ICGC	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	Q01094	E2F1	P49841	GSK3B	S121	E124Q	124	Missense	distal	3	no	6.711	6.692	EPSD	TCGA;ICGC;COSMIC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	Q01094	E2F1	P49841	GSK3B	S121	R127H	127	Missense	distal	6	no	6.711	6.705	EPSD	TCGA;ICGC;COSMIC;GDSC;CCLE	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	Q01094	E2F1	P49841	GSK3B	S131	E124Q	124	Missense	distal	-7	no	6.065	6.047	EPSD	TCGA;ICGC;COSMIC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	Q01094	E2F1	P49841	GSK3B	S131	R127H	127	Missense	distal	-4	no	6.065	6.164	EPSD	TCGA;ICGC;COSMIC;GDSC;CCLE	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	Q01094	E2F1	P49841	GSK3B	S131	R138C	138	Missense	distal	7	no	6.065	6.019	EPSD	TCGA;ICGC;COSMIC;GDSC;CCLE	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	Q01094	E2F1	P49841	GSK3B	S307	I306V	306	Missense	proximal	-1	no	8.116	8.314	EPSD	TCGA;ICGC;COSMIC	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	Q01094	E2F1	P49841	GSK3B	T311	I306V	306	Missense	distal	-5	no	7.138	7.246	EPSD	TCGA;ICGC;COSMIC	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	Q01094	E2F1	P49841	GSK3B	S313	I306V	306	Missense	distal	-7	no	6.819	6.813	EPSD	TCGA;ICGC;COSMIC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	Q01094	E2F1	P49841	GSK3B	S352	P346L	346	Missense	distal	-6	no	6.413	6.391	EPSD	TCGA;ICGC;COSMIC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	Q01094	E2F1	P49841	GSK3B	S403	H406Y	406	Missense	distal	3	no	9.524	9.130	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	Q01094	E2F1	P49841	GSK3B	T433	D426N	426	Missense	distal	-7	no	6.093	6.096	PhosphoSitePlus;EPSD	TCGA;ICGC	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	Q15746	MYLK	P49841	GSK3B	S18	D20N	20	Missense	proximal	2	no	8.033	7.409	EPSD	TCGA;ICGC;COSMIC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	Q15746	MYLK	P49841	GSK3B	S324	T331M	331	Missense	distal	7	no	6.466	6.894	EPSD	TCGA;ICGC;COSMIC	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	Q15746	MYLK	P49841	GSK3B	S328	T331M	331	Missense	distal	3	no	9.091	8.932	EPSD	TCGA;ICGC;COSMIC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	Q15746	MYLK	P49841	GSK3B	T335	T331M	331	Missense	distal	-4	no	6.367	5.642	EPSD	TCGA;ICGC;COSMIC	6.007	Loss
CMGC_GSK_GSK3B_ST	Q15746	MYLK	P49841	GSK3B	T335	T341N	341	Missense	distal	6	no	6.367	6.358	EPSD	TCGA;ICGC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	Q15746	MYLK	P49841	GSK3B	S365	R371K	371	Missense	distal	6	no	8.153	8.152	EPSD	TCGA;ICGC;COSMIC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	Q15746	MYLK	P49841	GSK3B	S947	D952N	952	Missense	distal	5	no	7.383	6.956	EPSD	TCGA;ICGC;COSMIC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	Q15746	MYLK	P49841	GSK3B	S947	E940Q	940	Missense	distal	-7	no	7.383	7.365	EPSD	TCGA;ICGC;COSMIC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	Q15746	MYLK	P49841	GSK3B	S947	D952A	952	Missense	distal	5	no	7.383	7.202	EPSD	TCGA;ICGC;COSMIC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	Q15746	MYLK	P49841	GSK3B	S947	E942K	942	Missense	distal	-5	no	7.383	7.152	EPSD	TCGA;ICGC;COSMIC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	Q15746	MYLK	P49841	GSK3B	S947	R954C	954	Missense	distal	7	no	7.383	7.337	EPSD	TCGA;ICGC;COSMIC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	Q15746	MYLK	P49841	GSK3B	S947	E940D	940	Missense	distal	-7	no	7.383	7.353	EPSD	TCGA;ICGC;COSMIC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	Q15746	MYLK	P49841	GSK3B	S1093	F1100L	1100	Missense	distal	7	no	6.013	5.921	EPSD	TCGA;ICGC;COSMIC	6.007	Loss
CMGC_GSK_GSK3B_ST	Q15746	MYLK	P49841	GSK3B	S1093	D1086Y	1086	Missense	distal	-7	no	6.013	6.039	EPSD	TCGA;ICGC	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	Q15746	MYLK	P49841	GSK3B	S1147	S1154Y	1154	Missense	distal	7	no	5.770	6.212	EPSD	TCGA;ICGC;COSMIC	6.007	Gain
CMGC_GSK_GSK3B_ST	Q15746	MYLK	P49841	GSK3B	T1230	M1236I	1236	Missense	distal	6	no	7.083	7.088	EPSD	TCGA	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	Q15746	MYLK	P49841	GSK3B	T1230	P1237S	1237	Missense	distal	7	no	7.083	7.147	EPSD	TCGA;ICGC;COSMIC	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	Q15746	MYLK	P49841	GSK3B	T1230	A1235V	1235	Missense	distal	5	no	7.083	6.657	EPSD	TCGA;ICGC;COSMIC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	Q15746	MYLK	P49841	GSK3B	T1230	M1236L	1236	Missense	distal	6	no	7.083	7.084	EPSD	TCGA;ICGC;COSMIC	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	Q15746	MYLK	P49841	GSK3B	S1419	S1416I	1416	Missense	distal	-3	no	6.665	6.779	EPSD	TCGA;ICGC	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	Q15746	MYLK	P49841	GSK3B	S1419	E1426D	1426	Missense	distal	7	no	6.665	6.681	EPSD	TCGA;ICGC;COSMIC	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	Q15746	MYLK	P49841	GSK3B	T1423	K1427T	1427	Missense	distal	4	no	4.764	7.098	EPSD	TCGA;ICGC;COSMIC	6.007	Gain
CMGC_GSK_GSK3B_ST	Q15746	MYLK	P49841	GSK3B	S1659	D1664G	1664	Missense	distal	5	no	8.263	8.199	EPSD	TCGA;ICGC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	Q15746	MYLK	P49841	GSK3B	S1772	L1767I	1767	Missense	distal	-5	no	8.059	8.423	EPSD	TCGA	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	Q15746	MYLK	P49841	GSK3B	S1776	P1780S	1780	Missense	distal	4	no	8.990	11.961	PhosphoSitePlus	TCGA;COSMIC	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	Q15746	MYLK	P49841	GSK3B	S1779	P1780S	1780	Missense	proximal	1	no	8.264	4.419	EPSD	TCGA;COSMIC	6.007	Loss
CMGC_GSK_GSK3B_ST	Q15746	MYLK	P49841	GSK3B	S1848	D1845H	1845	Missense	distal	-3	no	6.677	6.743	EPSD	TCGA;COSMIC	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	Q15746	MYLK	P49841	GSK3B	S1848	F1855L	1855	Missense	distal	7	no	6.677	6.585	EPSD	TCGA;COSMIC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	Q15746	MYLK	P49841	GSK3B	S1848	R1853H	1853	Missense	distal	5	no	6.677	5.688	EPSD	TCGA;COSMIC	6.007	Loss
CMGC_GSK_GSK3B_ST	P20393	NR1D1	P49841	GSK3B	S19	V13I	13	Missense	distal	-6	no	8.683	8.688	EPSD	TCGA;ICGC;COSMIC	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	P20393	NR1D1	P49841	GSK3B	S23	E30Q	30	Missense	distal	7	no	9.588	9.639	EPSD	TCGA;ICGC;COSMIC	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	P20393	NR1D1	P49841	GSK3B	S23	E30D	30	Missense	distal	7	no	9.588	9.604	EPSD	TCGA;ICGC	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	P20393	NR1D1	P49841	GSK3B	S55	S55Y	55	Missense	central	0	yes	10.392	0.000	PhosphoSitePlus;EPSD	TCGA;ICGC	6.007	Loss
CMGC_GSK_GSK3B_ST	P20393	NR1D1	P49841	GSK3B	S59	P64L	64	Missense	distal	5	no	6.607	5.327	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	6.007	Loss
CMGC_GSK_GSK3B_ST	P20393	NR1D1	P49841	GSK3B	S59	S55Y	55	Missense	distal	-4	no	6.607	5.807	EPSD;PhosphoSitePlus	TCGA;ICGC	6.007	Loss
CMGC_GSK_GSK3B_ST	P20393	NR1D1	P49841	GSK3B	S84	S84L	84	Missense	central	0	yes	7.876	0.000	EPSD	TCGA;ICGC;COSMIC	6.007	Loss
CMGC_GSK_GSK3B_ST	P20393	NR1D1	P49841	GSK3B	S84	S88L	88	Missense	distal	4	no	7.876	5.159	EPSD	TCGA;ICGC;COSMIC	6.007	Loss
CMGC_GSK_GSK3B_ST	P20393	NR1D1	P49841	GSK3B	S84	D78Y	78	Missense	distal	-6	no	7.876	7.815	EPSD	TCGA	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	P20393	NR1D1	P49841	GSK3B	S86	S84L	84	Missense	proximal	-2	no	6.187	6.113	EPSD	TCGA;ICGC;COSMIC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	P20393	NR1D1	P49841	GSK3B	S86	S88L	88	Missense	proximal	2	no	6.187	6.247	EPSD	TCGA;ICGC;COSMIC	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	P20393	NR1D1	P49841	GSK3B	S87	S84L	84	Missense	distal	-3	no	7.104	7.114	EPSD	TCGA;ICGC;COSMIC	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	P20393	NR1D1	P49841	GSK3B	S87	S88L	88	Missense	proximal	1	no	7.104	8.089	EPSD	TCGA;ICGC;COSMIC	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	P20393	NR1D1	P49841	GSK3B	S278	E282Q	282	Missense	distal	4	no	11.121	9.578	EPSD	TCGA;ICGC;COSMIC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	P20393	NR1D1	P49841	GSK3B	S280	E282Q	282	Missense	proximal	2	no	7.768	8.078	EPSD	TCGA;ICGC;COSMIC	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	P20393	NR1D1	P49841	GSK3B	S322	S322N	322	Missense	central	0	yes	9.126	0.000	EPSD	TCGA;ICGC;COSMIC	6.007	Loss
CMGC_GSK_GSK3B_ST	Q9NYF8	BCLAF1	P49841	GSK3B	S6	S4F	4	Missense	proximal	-2	no	7.649	7.319	EPSD	TCGA;ICGC;COSMIC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	Q9NYF8	BCLAF1	P49841	GSK3B	S6	R3H	3	Missense	distal	-3	no	7.649	7.593	EPSD	TCGA;ICGC;COSMIC;CCLE	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	Q9NYF8	BCLAF1	P49841	GSK3B	S6	R12K	12	Missense	distal	6	no	7.649	7.648	EPSD	TCGA;ICGC;COSMIC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	Q9NYF8	BCLAF1	P49841	GSK3B	S6	S8L	8	Missense	proximal	2	no	7.649	7.709	EPSD	TCGA;ICGC;COSMIC	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	Q9NYF8	BCLAF1	P49841	GSK3B	S6	R3C	3	Missense	distal	-3	no	7.649	7.584	EPSD	TCGA;ICGC;COSMIC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	Q9NYF8	BCLAF1	P49841	GSK3B	S15	R16I	16	Missense	proximal	1	no	7.933	6.372	EPSD	TCGA;ICGC;COSMIC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	Q9NYF8	BCLAF1	P49841	GSK3B	S15	S21Y	21	Missense	distal	6	no	7.933	7.927	EPSD	TCGA;ICGC;COSMIC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	Q9NYF8	BCLAF1	P49841	GSK3B	S15	Q18L	18	Missense	distal	3	no	7.933	7.671	EPSD	TCGA;ICGC;COSMIC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	Q9NYF8	BCLAF1	P49841	GSK3B	S15	R12K	12	Missense	distal	-3	no	7.933	7.788	EPSD	TCGA;ICGC;COSMIC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	Q9NYF8	BCLAF1	P49841	GSK3B	S15	R22Q	22	Missense	distal	7	no	7.933	7.586	EPSD	TCGA;ICGC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	Q9NYF8	BCLAF1	P49841	GSK3B	S19	R16I	16	Missense	distal	-3	no	7.212	7.157	EPSD	TCGA;ICGC;COSMIC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	Q9NYF8	BCLAF1	P49841	GSK3B	S19	S21Y	21	Missense	proximal	2	no	7.212	6.980	EPSD	TCGA;ICGC;COSMIC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	Q9NYF8	BCLAF1	P49841	GSK3B	S19	Q18L	18	Missense	proximal	-1	no	7.212	7.244	EPSD	TCGA;ICGC;COSMIC	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	Q9NYF8	BCLAF1	P49841	GSK3B	S19	R12K	12	Missense	distal	-7	no	7.212	7.216	EPSD	TCGA;ICGC;COSMIC	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	Q9NYF8	BCLAF1	P49841	GSK3B	S19	R24I	24	Missense	distal	5	no	7.212	6.229	EPSD	TCGA;ICGC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	Q9NYF8	BCLAF1	P49841	GSK3B	S19	R22Q	22	Missense	distal	3	no	7.212	7.545	EPSD	TCGA;ICGC	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	Q9NYF8	BCLAF1	P49841	GSK3B	S36	Y34H	34	Missense	proximal	-2	no	8.864	9.078	EPSD	TCGA;ICGC;COSMIC	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	Q9NYF8	BCLAF1	P49841	GSK3B	S36	R33Q	33	Missense	distal	-3	no	8.864	8.725	EPSD	TCGA;ICGC;COSMIC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	Q9NYF8	BCLAF1	P49841	GSK3B	S38	Y34H	34	Missense	distal	-4	no	6.594	6.306	EPSD	TCGA;ICGC;COSMIC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	Q9NYF8	BCLAF1	P49841	GSK3B	S38	R33Q	33	Missense	distal	-5	no	6.594	6.039	EPSD	TCGA;ICGC;COSMIC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	Q9NYF8	BCLAF1	P49841	GSK3B	S40	Y34H	34	Missense	distal	-6	no	9.026	9.079	EPSD	TCGA;ICGC;COSMIC	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	Q9NYF8	BCLAF1	P49841	GSK3B	S40	R33Q	33	Missense	distal	-7	no	9.026	9.023	EPSD	TCGA;ICGC;COSMIC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	Q9NYF8	BCLAF1	P49841	GSK3B	S44	R51C	51	Missense	distal	7	no	8.536	8.490	EPSD	TCGA;ICGC;COSMIC;GDSC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	Q9NYF8	BCLAF1	P49841	GSK3B	S44	R51H	51	Missense	distal	7	no	8.536	8.724	EPSD	TCGA;ICGC;COSMIC	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	Q9NYF8	BCLAF1	P49841	GSK3B	S46	R51C	51	Missense	distal	5	no	6.579	5.023	EPSD	TCGA;ICGC;COSMIC;GDSC	6.007	Loss
CMGC_GSK_GSK3B_ST	Q9NYF8	BCLAF1	P49841	GSK3B	S46	R51H	51	Missense	distal	5	no	6.579	5.590	EPSD	TCGA;ICGC;COSMIC	6.007	Loss
CMGC_GSK_GSK3B_ST	Q9NYF8	BCLAF1	P49841	GSK3B	S48	R51C	51	Missense	distal	3	no	6.141	6.296	EPSD	TCGA;ICGC;COSMIC;GDSC	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	Q9NYF8	BCLAF1	P49841	GSK3B	S48	R51H	51	Missense	distal	3	no	6.141	6.483	EPSD	TCGA;ICGC;COSMIC	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	Q9NYF8	BCLAF1	P49841	GSK3B	S54	R51C	51	Missense	distal	-3	no	6.057	5.992	EPSD	TCGA;ICGC;COSMIC;GDSC	6.007	Loss
CMGC_GSK_GSK3B_ST	Q9NYF8	BCLAF1	P49841	GSK3B	S54	R59C	59	Missense	distal	5	no	6.057	4.501	EPSD	TCGA;ICGC;COSMIC	6.007	Loss
CMGC_GSK_GSK3B_ST	Q9NYF8	BCLAF1	P49841	GSK3B	S54	R51H	51	Missense	distal	-3	no	6.057	6.001	EPSD	TCGA;ICGC;COSMIC	6.007	Loss
CMGC_GSK_GSK3B_ST	Q9NYF8	BCLAF1	P49841	GSK3B	S54	D60N	60	Missense	distal	6	no	6.057	6.058	EPSD	TCGA;ICGC;COSMIC	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	Q9NYF8	BCLAF1	P49841	GSK3B	S104	S102C	102	Missense	proximal	-2	no	7.978	7.667	EPSD	TCGA;ICGC;COSMIC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	Q9NYF8	BCLAF1	P49841	GSK3B	S104	S104C	104	Missense	central	0	yes	7.978	0.000	EPSD	TCGA	6.007	Loss
CMGC_GSK_GSK3B_ST	Q9NYF8	BCLAF1	P49841	GSK3B	S104	R103G	103	Missense	proximal	-1	no	7.978	8.122	EPSD	TCGA;ICGC;COSMIC	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	Q9NYF8	BCLAF1	P49841	GSK3B	S104	R109S	109	Missense	distal	5	no	7.978	7.662	EPSD	TCGA;ICGC;COSMIC;GDSC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	Q9NYF8	BCLAF1	P49841	GSK3B	S104	R103S	103	Missense	proximal	-1	no	7.978	8.116	EPSD	TCGA;ICGC;COSMIC	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	Q9NYF8	BCLAF1	P49841	GSK3B	S104	R99G	99	Missense	distal	-5	no	7.978	7.747	EPSD	TCGA;COSMIC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	Q9NYF8	BCLAF1	P49841	GSK3B	S104	R109L	109	Missense	distal	5	no	7.978	7.335	EPSD	TCGA;ICGC;COSMIC;GDSC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	Q9NYF8	BCLAF1	P49841	GSK3B	S104	S110L	110	Missense	distal	6	no	7.978	7.974	EPSD	TCGA;COSMIC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	Q9NYF8	BCLAF1	P49841	GSK3B	S104	R109C	109	Missense	distal	5	no	7.978	6.422	EPSD	TCGA;ICGC;COSMIC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	Q9NYF8	BCLAF1	P49841	GSK3B	S104	R111H	111	Missense	distal	7	no	7.978	8.166	EPSD	TCGA;COSMIC	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	Q9NYF8	BCLAF1	P49841	GSK3B	S104	R99K	99	Missense	distal	-5	no	7.978	7.481	EPSD	TCGA;COSMIC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	Q9NYF8	BCLAF1	P49841	GSK3B	S114	V120F	120	Missense	distal	6	no	7.790	7.787	EPSD	TCGA;COSMIC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	Q9NYF8	BCLAF1	P49841	GSK3B	S114	R118I	118	Missense	distal	4	no	7.790	7.505	EPSD	TCGA;COSMIC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	Q9NYF8	BCLAF1	P49841	GSK3B	S114	R118K	118	Missense	distal	4	no	7.790	7.625	EPSD	TCGA;ICGC;COSMIC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	Q9NYF8	BCLAF1	P49841	GSK3B	S114	R109S	109	Missense	distal	-5	no	7.790	7.092	EPSD	TCGA;ICGC;COSMIC;GDSC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	Q9NYF8	BCLAF1	P49841	GSK3B	S114	R109L	109	Missense	distal	-5	no	7.790	7.201	EPSD	TCGA;ICGC;COSMIC;GDSC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	Q9NYF8	BCLAF1	P49841	GSK3B	S114	S110L	110	Missense	distal	-4	no	7.790	6.439	EPSD	TCGA;COSMIC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	Q9NYF8	BCLAF1	P49841	GSK3B	S114	R109C	109	Missense	distal	-5	no	7.790	7.611	EPSD	TCGA;ICGC;COSMIC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	Q9NYF8	BCLAF1	P49841	GSK3B	S114	R117K	117	Missense	distal	3	no	7.790	8.034	EPSD	TCGA;ICGC;COSMIC	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	Q9NYF8	BCLAF1	P49841	GSK3B	S114	V120L	120	Missense	distal	6	no	7.790	7.795	EPSD	TCGA;COSMIC	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	Q9NYF8	BCLAF1	P49841	GSK3B	S114	R111H	111	Missense	distal	-3	no	7.790	7.733	EPSD	TCGA;COSMIC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	Q9NYF8	BCLAF1	P49841	GSK3B	S121	V120F	120	Missense	proximal	-1	no	7.333	7.154	EPSD	TCGA;COSMIC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	Q9NYF8	BCLAF1	P49841	GSK3B	S121	R118I	118	Missense	distal	-3	no	7.333	7.278	EPSD	TCGA;COSMIC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	Q9NYF8	BCLAF1	P49841	GSK3B	S121	R118K	118	Missense	distal	-3	no	7.333	7.188	EPSD	TCGA;ICGC;COSMIC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	Q9NYF8	BCLAF1	P49841	GSK3B	S121	R128K	128	Missense	distal	7	no	7.333	6.826	EPSD	TCGA;ICGC;COSMIC;GDSC;CCLE	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	Q9NYF8	BCLAF1	P49841	GSK3B	S121	R128I	128	Missense	distal	7	no	7.333	7.231	EPSD	TCGA;COSMIC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	Q9NYF8	BCLAF1	P49841	GSK3B	S121	S125F	125	Missense	distal	4	no	7.333	3.719	EPSD	TCGA;ICGC;COSMIC;GDSC	6.007	Loss
CMGC_GSK_GSK3B_ST	Q9NYF8	BCLAF1	P49841	GSK3B	S121	R117K	117	Missense	distal	-4	no	7.333	7.655	EPSD	TCGA;ICGC;COSMIC	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	Q9NYF8	BCLAF1	P49841	GSK3B	S121	V120L	120	Missense	proximal	-1	no	7.333	7.210	EPSD	TCGA;COSMIC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	Q9NYF8	BCLAF1	P49841	GSK3B	S121	R126I	126	Missense	distal	5	no	7.333	6.350	EPSD	TCGA;ICGC;COSMIC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	Q9NYF8	BCLAF1	P49841	GSK3B	S121	R124S	124	Missense	distal	3	no	7.333	7.704	EPSD	TCGA	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	Q9NYF8	BCLAF1	P49841	GSK3B	S125	V120F	120	Missense	distal	-5	no	8.877	8.857	EPSD	TCGA;COSMIC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	Q9NYF8	BCLAF1	P49841	GSK3B	S125	R130H	130	Missense	distal	5	no	8.877	7.888	EPSD	TCGA;COSMIC;GDSC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	Q9NYF8	BCLAF1	P49841	GSK3B	S125	R131Q	131	Missense	distal	6	no	8.877	8.878	EPSD	TCGA;ICGC;COSMIC;GDSC	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	Q9NYF8	BCLAF1	P49841	GSK3B	S125	R118I	118	Missense	distal	-7	no	8.877	8.887	EPSD	TCGA;COSMIC	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	Q9NYF8	BCLAF1	P49841	GSK3B	S125	R118K	118	Missense	distal	-7	no	8.877	8.880	EPSD	TCGA;ICGC;COSMIC	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	Q9NYF8	BCLAF1	P49841	GSK3B	S125	R128K	128	Missense	distal	3	no	8.877	9.121	EPSD	TCGA;ICGC;COSMIC;GDSC;CCLE	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	Q9NYF8	BCLAF1	P49841	GSK3B	S125	R128I	128	Missense	distal	3	no	8.877	8.828	EPSD	TCGA;COSMIC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	Q9NYF8	BCLAF1	P49841	GSK3B	S125	R131P	131	Missense	distal	6	no	8.877	8.884	EPSD	TCGA;ICGC;COSMIC	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	Q9NYF8	BCLAF1	P49841	GSK3B	S125	S125F	125	Missense	central	0	yes	8.877	0.000	EPSD	TCGA;ICGC;COSMIC;GDSC	6.007	Loss
CMGC_GSK_GSK3B_ST	Q9NYF8	BCLAF1	P49841	GSK3B	S125	V120L	120	Missense	distal	-5	no	8.877	8.406	EPSD	TCGA;COSMIC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	Q9NYF8	BCLAF1	P49841	GSK3B	S125	R126I	126	Missense	proximal	1	no	8.877	7.316	EPSD	TCGA;ICGC;COSMIC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	Q9NYF8	BCLAF1	P49841	GSK3B	S125	S129A	129	Missense	distal	4	no	8.877	6.465	EPSD	TCGA;ICGC;COSMIC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	Q9NYF8	BCLAF1	P49841	GSK3B	S125	R124S	124	Missense	proximal	-1	no	8.877	9.014	EPSD	TCGA	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	Q9NYF8	BCLAF1	P49841	GSK3B	S136	R134I	134	Missense	proximal	-2	no	5.943	6.048	EPSD	TCGA;ICGC	6.007	Gain
CMGC_GSK_GSK3B_ST	Q9NYF8	BCLAF1	P49841	GSK3B	S138	R131Q	131	Missense	distal	-7	no	10.710	10.707	EPSD	TCGA;ICGC;COSMIC;GDSC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	Q9NYF8	BCLAF1	P49841	GSK3B	S138	R137M	137	Missense	proximal	-1	no	10.710	10.797	EPSD	TCGA;ICGC;COSMIC	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	Q9NYF8	BCLAF1	P49841	GSK3B	S138	R131P	131	Missense	distal	-7	no	10.710	10.690	EPSD	TCGA;ICGC;COSMIC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	Q9NYF8	BCLAF1	P49841	GSK3B	S138	R131L	131	Missense	distal	-7	no	10.710	10.692	EPSD	TCGA;COSMIC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	Q9NYF8	BCLAF1	P49841	GSK3B	S138	S141L	141	Missense	distal	3	no	10.710	10.410	EPSD	TCGA;ICGC;COSMIC;GDSC;CCLE	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	Q9NYF8	BCLAF1	P49841	GSK3B	S138	R145C	145	Missense	distal	7	no	10.710	10.664	EPSD	TCGA;COSMIC;CCLE	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	Q9NYF8	BCLAF1	P49841	GSK3B	S138	S144A	144	Missense	distal	6	no	10.710	10.708	EPSD	TCGA;COSMIC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	Q9NYF8	BCLAF1	P49841	GSK3B	S138	R134I	134	Missense	distal	-4	no	10.710	9.414	EPSD	TCGA;ICGC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	Q9NYF8	BCLAF1	P49841	GSK3B	S138	S136C	136	Missense	proximal	-2	no	10.710	10.399	EPSD	TCGA;COSMIC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	Q9NYF8	BCLAF1	P49841	GSK3B	S143	S148Y	148	Missense	distal	5	no	6.597	5.599	EPSD	TCGA;COSMIC	6.007	Loss
CMGC_GSK_GSK3B_ST	Q9NYF8	BCLAF1	P49841	GSK3B	S143	R137M	137	Missense	distal	-6	no	6.597	6.602	EPSD	TCGA;ICGC;COSMIC	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	Q9NYF8	BCLAF1	P49841	GSK3B	S143	S147L	147	Missense	distal	4	no	6.597	3.880	EPSD	TCGA;ICGC;COSMIC	6.007	Loss
CMGC_GSK_GSK3B_ST	Q9NYF8	BCLAF1	P49841	GSK3B	S143	Y150H	150	Missense	distal	7	no	6.597	6.781	EPSD	TCGA;ICGC;COSMIC;GDSC;CCLE	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	Q9NYF8	BCLAF1	P49841	GSK3B	S143	S141L	141	Missense	proximal	-2	no	6.597	6.523	EPSD	TCGA;ICGC;COSMIC;GDSC;CCLE	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	Q9NYF8	BCLAF1	P49841	GSK3B	S143	R145C	145	Missense	proximal	2	no	6.597	6.087	EPSD	TCGA;COSMIC;CCLE	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	Q9NYF8	BCLAF1	P49841	GSK3B	S143	S144A	144	Missense	proximal	1	no	6.597	6.710	EPSD	TCGA;COSMIC	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	Q9NYF8	BCLAF1	P49841	GSK3B	S143	P149L	149	Missense	distal	6	no	6.597	6.591	EPSD	TCGA;ICGC;COSMIC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	Q9NYF8	BCLAF1	P49841	GSK3B	S143	S136C	136	Missense	distal	-7	no	6.597	6.620	EPSD	TCGA;COSMIC	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	Q9NYF8	BCLAF1	P49841	GSK3B	S147	S148Y	148	Missense	proximal	1	no	6.286	6.812	EPSD	TCGA;COSMIC	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	Q9NYF8	BCLAF1	P49841	GSK3B	S147	S147L	147	Missense	central	0	yes	6.286	0.000	EPSD	TCGA;ICGC;COSMIC	6.007	Loss
CMGC_GSK_GSK3B_ST	Q9NYF8	BCLAF1	P49841	GSK3B	S147	Y150H	150	Missense	distal	3	no	6.286	6.679	EPSD	TCGA;ICGC;COSMIC;GDSC;CCLE	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	Q9NYF8	BCLAF1	P49841	GSK3B	S147	S141L	141	Missense	distal	-6	no	6.286	6.284	EPSD	TCGA;ICGC;COSMIC;GDSC;CCLE	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	Q9NYF8	BCLAF1	P49841	GSK3B	S147	R145C	145	Missense	proximal	-2	no	6.286	6.090	EPSD	TCGA;COSMIC;CCLE	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	Q9NYF8	BCLAF1	P49841	GSK3B	S147	K152R	152	Missense	distal	5	no	6.286	7.161	EPSD	TCGA;ICGC;COSMIC	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	Q9NYF8	BCLAF1	P49841	GSK3B	S147	S144A	144	Missense	distal	-3	no	6.286	6.306	EPSD	TCGA;COSMIC	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	Q9NYF8	BCLAF1	P49841	GSK3B	S147	P154L	154	Missense	distal	7	no	6.286	6.335	EPSD	TCGA;ICGC;COSMIC	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	Q9NYF8	BCLAF1	P49841	GSK3B	S147	P149L	149	Missense	proximal	2	no	6.286	5.902	EPSD	TCGA;ICGC;COSMIC	6.007	Loss
CMGC_GSK_GSK3B_ST	Q9NYF8	BCLAF1	P49841	GSK3B	S147	S151N	151	Missense	distal	4	no	6.286	2.676	EPSD	TCGA	6.007	Loss
CMGC_GSK_GSK3B_ST	Q9NYF8	BCLAF1	P49841	GSK3B	S148	S148Y	148	Missense	central	0	yes	7.086	0.000	EPSD	TCGA;COSMIC	6.007	Loss
CMGC_GSK_GSK3B_ST	Q9NYF8	BCLAF1	P49841	GSK3B	S148	S147L	147	Missense	proximal	-1	no	7.086	7.011	EPSD	TCGA;ICGC;COSMIC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	Q9NYF8	BCLAF1	P49841	GSK3B	S148	Y150H	150	Missense	proximal	2	no	7.086	6.993	EPSD	TCGA;ICGC;COSMIC;GDSC;CCLE	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	Q9NYF8	BCLAF1	P49841	GSK3B	S148	R145C	145	Missense	distal	-3	no	7.086	7.021	EPSD	TCGA;COSMIC;CCLE	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	Q9NYF8	BCLAF1	P49841	GSK3B	S148	K152R	152	Missense	distal	4	no	7.086	7.251	EPSD	TCGA;ICGC;COSMIC	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	Q9NYF8	BCLAF1	P49841	GSK3B	S148	S144A	144	Missense	distal	-4	no	7.086	5.926	EPSD	TCGA;COSMIC	6.007	Loss
CMGC_GSK_GSK3B_ST	Q9NYF8	BCLAF1	P49841	GSK3B	S148	P154L	154	Missense	distal	6	no	7.086	7.079	EPSD	TCGA;ICGC;COSMIC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	Q9NYF8	BCLAF1	P49841	GSK3B	S148	P149L	149	Missense	proximal	1	no	7.086	4.226	EPSD	TCGA;ICGC;COSMIC	6.007	Loss
CMGC_GSK_GSK3B_ST	Q9NYF8	BCLAF1	P49841	GSK3B	S148	S151N	151	Missense	distal	3	no	7.086	7.134	EPSD	TCGA	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	Q9NYF8	BCLAF1	P49841	GSK3B	S153	S148Y	148	Missense	distal	-5	no	7.955	8.607	EPSD	TCGA;COSMIC	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	Q9NYF8	BCLAF1	P49841	GSK3B	S153	S147L	147	Missense	distal	-6	no	7.955	7.953	EPSD	TCGA;ICGC;COSMIC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	Q9NYF8	BCLAF1	P49841	GSK3B	S153	Y150H	150	Missense	distal	-3	no	7.955	7.926	EPSD	TCGA;ICGC;COSMIC;GDSC;CCLE	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	Q9NYF8	BCLAF1	P49841	GSK3B	S153	G160W	160	Missense	distal	7	no	7.955	8.481	EPSD	TCGA;ICGC;COSMIC	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	Q9NYF8	BCLAF1	P49841	GSK3B	S153	K152R	152	Missense	proximal	-1	no	7.955	7.762	EPSD	TCGA;ICGC;COSMIC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	Q9NYF8	BCLAF1	P49841	GSK3B	S153	P154L	154	Missense	proximal	1	no	7.955	5.094	EPSD	TCGA;ICGC;COSMIC	6.007	Loss
CMGC_GSK_GSK3B_ST	Q9NYF8	BCLAF1	P49841	GSK3B	S153	P149L	149	Missense	distal	-4	no	7.955	7.168	EPSD	TCGA;ICGC;COSMIC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	Q9NYF8	BCLAF1	P49841	GSK3B	S153	S151N	151	Missense	proximal	-2	no	7.955	7.726	EPSD	TCGA	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	Q9NYF8	BCLAF1	P49841	GSK3B	S153	R158K	158	Missense	distal	5	no	7.955	7.080	EPSD	TCGA;COSMIC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	Q9NYF8	BCLAF1	P49841	GSK3B	S177	G171R	171	Missense	distal	-6	no	10.456	10.382	EPSD	TCGA;ICGC;COSMIC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	Q9NYF8	BCLAF1	P49841	GSK3B	S177	P173L	173	Missense	distal	-4	no	10.456	9.669	EPSD	TCGA;ICGC;COSMIC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	Q9NYF8	BCLAF1	P49841	GSK3B	S177	Q184L	184	Missense	distal	7	no	10.456	10.352	EPSD	TCGA;COSMIC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	Q9NYF8	BCLAF1	P49841	GSK3B	S177	E170K	170	Missense	distal	-7	no	10.456	10.445	EPSD	TCGA;COSMIC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	Q9NYF8	BCLAF1	P49841	GSK3B	S177	E170G	170	Missense	distal	-7	no	10.456	10.421	EPSD	TCGA;COSMIC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	Q9NYF8	BCLAF1	P49841	GSK3B	S205	E201K	201	Missense	distal	-4	no	6.387	6.119	EPSD	TCGA;ICGC;COSMIC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	Q9NYF8	BCLAF1	P49841	GSK3B	S205	D200N	200	Missense	distal	-5	no	6.387	5.822	EPSD	TCGA;ICGC;COSMIC	6.007	Loss
CMGC_GSK_GSK3B_ST	Q9NYF8	BCLAF1	P49841	GSK3B	S222	P229S	229	Missense	distal	7	no	6.497	6.560	EPSD	TCGA;COSMIC	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	Q9NYF8	BCLAF1	P49841	GSK3B	S222	R224I	224	Missense	proximal	2	no	6.497	6.539	EPSD	TCGA;ICGC;COSMIC	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	Q9NYF8	BCLAF1	P49841	GSK3B	S222	S225L	225	Missense	distal	3	no	6.497	6.196	EPSD	TCGA;ICGC;COSMIC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	Q9NYF8	BCLAF1	P49841	GSK3B	S222	N221D	221	Missense	proximal	-1	no	6.497	6.375	EPSD	TCGA;ICGC;COSMIC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	Q9NYF8	BCLAF1	P49841	GSK3B	S222	N221I	221	Missense	proximal	-1	no	6.497	6.286	EPSD	TCGA;ICGC;COSMIC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	Q9NYF8	BCLAF1	P49841	GSK3B	S222	G215C	215	Missense	distal	-7	no	6.497	6.522	EPSD	TCGA;COSMIC	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	Q9NYF8	BCLAF1	P49841	GSK3B	S225	P229S	229	Missense	distal	4	no	6.242	9.213	EPSD	TCGA;COSMIC	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	Q9NYF8	BCLAF1	P49841	GSK3B	S225	S230L	230	Missense	distal	5	no	6.242	5.915	EPSD	TCGA;ICGC;COSMIC	6.007	Loss
CMGC_GSK_GSK3B_ST	Q9NYF8	BCLAF1	P49841	GSK3B	S225	R224I	224	Missense	proximal	-1	no	6.242	6.229	EPSD	TCGA;ICGC;COSMIC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	Q9NYF8	BCLAF1	P49841	GSK3B	S225	S228I	228	Missense	distal	3	no	6.242	5.821	EPSD	TCGA;COSMIC	6.007	Loss
CMGC_GSK_GSK3B_ST	Q9NYF8	BCLAF1	P49841	GSK3B	S225	S225L	225	Missense	central	0	yes	6.242	0.000	EPSD	TCGA;ICGC;COSMIC	6.007	Loss
CMGC_GSK_GSK3B_ST	Q9NYF8	BCLAF1	P49841	GSK3B	S225	N221D	221	Missense	distal	-4	no	6.242	6.939	EPSD	TCGA;ICGC;COSMIC	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	Q9NYF8	BCLAF1	P49841	GSK3B	S225	N221I	221	Missense	distal	-4	no	6.242	5.056	EPSD	TCGA;ICGC;COSMIC	6.007	Loss
CMGC_GSK_GSK3B_ST	Q9NYF8	BCLAF1	P49841	GSK3B	S228	P229S	229	Missense	proximal	1	no	7.154	3.309	EPSD	TCGA;COSMIC	6.007	Loss
CMGC_GSK_GSK3B_ST	Q9NYF8	BCLAF1	P49841	GSK3B	S228	S230L	230	Missense	proximal	2	no	7.154	7.214	EPSD	TCGA;ICGC;COSMIC	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	Q9NYF8	BCLAF1	P49841	GSK3B	S228	R224I	224	Missense	distal	-4	no	7.154	5.858	EPSD	TCGA;ICGC;COSMIC	6.007	Loss
CMGC_GSK_GSK3B_ST	Q9NYF8	BCLAF1	P49841	GSK3B	S228	S228I	228	Missense	central	0	yes	7.154	0.000	EPSD	TCGA;COSMIC	6.007	Loss
CMGC_GSK_GSK3B_ST	Q9NYF8	BCLAF1	P49841	GSK3B	S228	S225L	225	Missense	distal	-3	no	7.154	7.164	EPSD	TCGA;ICGC;COSMIC	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	Q9NYF8	BCLAF1	P49841	GSK3B	S228	N221D	221	Missense	distal	-7	no	7.154	7.151	EPSD	TCGA;ICGC;COSMIC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	Q9NYF8	BCLAF1	P49841	GSK3B	S228	P235L	235	Missense	distal	7	no	7.154	7.203	EPSD	TCGA;ICGC;COSMIC	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	Q9NYF8	BCLAF1	P49841	GSK3B	S228	N221I	221	Missense	distal	-7	no	7.154	7.176	EPSD	TCGA;ICGC;COSMIC	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	Q9NYF8	BCLAF1	P49841	GSK3B	S230	P229S	229	Missense	proximal	-1	no	8.932	8.876	EPSD	TCGA;COSMIC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	Q9NYF8	BCLAF1	P49841	GSK3B	S230	S230L	230	Missense	central	0	yes	8.932	0.000	EPSD	TCGA;ICGC;COSMIC	6.007	Loss
CMGC_GSK_GSK3B_ST	Q9NYF8	BCLAF1	P49841	GSK3B	S230	P236L	236	Missense	distal	6	no	8.932	8.926	EPSD	TCGA;COSMIC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	Q9NYF8	BCLAF1	P49841	GSK3B	S230	R224I	224	Missense	distal	-6	no	8.932	8.927	EPSD	TCGA;ICGC;COSMIC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	Q9NYF8	BCLAF1	P49841	GSK3B	S230	P236H	236	Missense	distal	6	no	8.932	8.921	EPSD	TCGA;ICGC;COSMIC;GDSC;CCLE	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	Q9NYF8	BCLAF1	P49841	GSK3B	S230	S228I	228	Missense	proximal	-2	no	8.932	8.922	EPSD	TCGA;COSMIC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	Q9NYF8	BCLAF1	P49841	GSK3B	S230	S225L	225	Missense	distal	-5	no	8.932	9.041	EPSD	TCGA;ICGC;COSMIC	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	Q9NYF8	BCLAF1	P49841	GSK3B	S230	S237R	237	Missense	distal	7	no	8.932	9.370	EPSD	TCGA;COSMIC	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	Q9NYF8	BCLAF1	P49841	GSK3B	S230	P235L	235	Missense	distal	5	no	8.932	7.652	EPSD	TCGA;ICGC;COSMIC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	Q9NYF8	BCLAF1	P49841	GSK3B	S239	A245S	245	Missense	distal	6	no	6.553	6.555	EPSD	TCGA;COSMIC	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	Q9NYF8	BCLAF1	P49841	GSK3B	S239	P236L	236	Missense	distal	-3	no	6.553	6.680	EPSD	TCGA;COSMIC	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	Q9NYF8	BCLAF1	P49841	GSK3B	S239	P236H	236	Missense	distal	-3	no	6.553	6.782	EPSD	TCGA;ICGC;COSMIC;GDSC;CCLE	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	Q9NYF8	BCLAF1	P49841	GSK3B	S239	P236T	236	Missense	distal	-3	no	6.553	6.695	EPSD	TCGA;COSMIC	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	Q9NYF8	BCLAF1	P49841	GSK3B	S239	P246S	246	Missense	distal	7	no	6.553	6.617	EPSD	TCGA;COSMIC	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	Q9NYF8	BCLAF1	P49841	GSK3B	S239	S240P	240	Missense	proximal	1	no	6.553	10.398	EPSD	TCGA;ICGC;COSMIC	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	Q9NYF8	BCLAF1	P49841	GSK3B	S239	S237R	237	Missense	proximal	-2	no	6.553	6.438	EPSD	TCGA;COSMIC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	Q9NYF8	BCLAF1	P49841	GSK3B	S239	P235L	235	Missense	distal	-4	no	6.553	5.767	EPSD	TCGA;ICGC;COSMIC	6.007	Loss
CMGC_GSK_GSK3B_ST	Q9NYF8	BCLAF1	P49841	GSK3B	S241	A245S	245	Missense	distal	4	no	4.867	7.279	EPSD	TCGA;COSMIC	6.007	Gain
CMGC_GSK_GSK3B_ST	Q9NYF8	BCLAF1	P49841	GSK3B	S243	M247T	247	Missense	distal	4	no	4.769	6.135	EPSD	TCGA;COSMIC	6.007	Gain
CMGC_GSK_GSK3B_ST	Q9NYF8	BCLAF1	P49841	GSK3B	S249	A245S	245	Missense	distal	-4	no	7.274	8.434	EPSD	TCGA;COSMIC	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	Q9NYF8	BCLAF1	P49841	GSK3B	S249	T250I	250	Missense	proximal	1	no	7.274	6.584	EPSD	TCGA;ICGC;COSMIC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	Q9NYF8	BCLAF1	P49841	GSK3B	S249	M247T	247	Missense	proximal	-2	no	7.274	7.632	EPSD	TCGA;COSMIC	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	Q9NYF8	BCLAF1	P49841	GSK3B	S249	H252P	252	Missense	distal	3	no	7.274	7.321	EPSD	TCGA;COSMIC	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	Q9NYF8	BCLAF1	P49841	GSK3B	S249	H252Q	252	Missense	distal	3	no	7.274	7.265	EPSD	TCGA;ICGC;COSMIC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	Q9NYF8	BCLAF1	P49841	GSK3B	S249	P246S	246	Missense	distal	-3	no	7.274	7.391	EPSD	TCGA;COSMIC	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	Q9NYF8	BCLAF1	P49841	GSK3B	S249	H252Y	252	Missense	distal	3	no	7.274	6.881	EPSD	TCGA;ICGC;COSMIC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	Q9NYF8	BCLAF1	P49841	GSK3B	S253	Q260E	260	Missense	distal	7	no	7.196	7.145	EPSD	TCGA;COSMIC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	Q9NYF8	BCLAF1	P49841	GSK3B	S253	T250I	250	Missense	distal	-3	no	7.196	7.285	EPSD	TCGA;ICGC;COSMIC	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	Q9NYF8	BCLAF1	P49841	GSK3B	S253	M247T	247	Missense	distal	-6	no	7.196	7.191	EPSD	TCGA;COSMIC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	Q9NYF8	BCLAF1	P49841	GSK3B	S253	H252P	252	Missense	proximal	-1	no	7.196	7.304	EPSD	TCGA;COSMIC	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	Q9NYF8	BCLAF1	P49841	GSK3B	S253	H252Q	252	Missense	proximal	-1	no	7.196	7.141	EPSD	TCGA;ICGC;COSMIC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	Q9NYF8	BCLAF1	P49841	GSK3B	S253	Q260L	260	Missense	distal	7	no	7.196	7.092	EPSD	TCGA;COSMIC;GDSC;CCLE	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	Q9NYF8	BCLAF1	P49841	GSK3B	S253	S259F	259	Missense	distal	6	no	7.196	7.184	EPSD	TCGA;COSMIC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	Q9NYF8	BCLAF1	P49841	GSK3B	S253	P246S	246	Missense	distal	-7	no	7.196	7.198	EPSD	TCGA;COSMIC	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	Q9NYF8	BCLAF1	P49841	GSK3B	S253	H252Y	252	Missense	proximal	-1	no	7.196	7.108	EPSD	TCGA;ICGC;COSMIC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	Q9NYF8	BCLAF1	P49841	GSK3B	T257	H252Y	252	Missense	distal	-5	no	5.770	6.255	EPSD	TCGA;ICGC;COSMIC	6.007	Gain
CMGC_GSK_GSK3B_ST	Q9NYF8	BCLAF1	P49841	GSK3B	S264	Q260E	260	Missense	distal	-4	no	7.837	8.070	EPSD	TCGA;COSMIC	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	Q9NYF8	BCLAF1	P49841	GSK3B	S264	H263L	263	Missense	proximal	-1	no	7.837	7.814	EPSD	TCGA;ICGC;COSMIC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	Q9NYF8	BCLAF1	P49841	GSK3B	S264	Q260L	260	Missense	distal	-4	no	7.837	7.317	EPSD	TCGA;COSMIC;GDSC;CCLE	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	Q9NYF8	BCLAF1	P49841	GSK3B	S264	S259F	259	Missense	distal	-5	no	7.837	8.397	EPSD	TCGA;COSMIC	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	Q9NYF8	BCLAF1	P49841	GSK3B	S264	S264F	264	Missense	central	0	yes	7.837	0.000	EPSD	TCGA;COSMIC	6.007	Loss
CMGC_GSK_GSK3B_ST	Q9NYF8	BCLAF1	P49841	GSK3B	S264	E270K	270	Missense	distal	6	no	7.837	7.838	EPSD	TCGA;COSMIC	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	Q9NYF8	BCLAF1	P49841	GSK3B	S268	H263L	263	Missense	distal	-5	no	8.909	8.851	EPSD	TCGA;ICGC;COSMIC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	Q9NYF8	BCLAF1	P49841	GSK3B	S268	S264F	264	Missense	distal	-4	no	8.909	7.755	EPSD	TCGA;COSMIC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	Q9NYF8	BCLAF1	P49841	GSK3B	S268	E270K	270	Missense	proximal	2	no	8.909	8.949	EPSD	TCGA;COSMIC	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	Q9NYF8	BCLAF1	P49841	GSK3B	S272	S276F	276	Missense	distal	4	no	7.067	3.453	EPSD	TCGA;ICGC;COSMIC;GDSC;CCLE	6.007	Loss
CMGC_GSK_GSK3B_ST	Q9NYF8	BCLAF1	P49841	GSK3B	S272	N279I	279	Missense	distal	7	no	7.067	7.280	EPSD	TCGA;ICGC;COSMIC	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	Q9NYF8	BCLAF1	P49841	GSK3B	S272	E270K	270	Missense	proximal	-2	no	7.067	7.036	EPSD	TCGA;COSMIC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	Q9NYF8	BCLAF1	P49841	GSK3B	S281	Y284C	284	Missense	distal	3	no	6.424	6.631	EPSD	TCGA;ICGC;COSMIC	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	Q9NYF8	BCLAF1	P49841	GSK3B	S281	S276F	276	Missense	distal	-5	no	6.424	6.984	EPSD	TCGA;ICGC;COSMIC;GDSC;CCLE	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	Q9NYF8	BCLAF1	P49841	GSK3B	S281	N279I	279	Missense	proximal	-2	no	6.424	6.642	EPSD	TCGA;ICGC;COSMIC	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	Q9NYF8	BCLAF1	P49841	GSK3B	S281	R283Q	283	Missense	proximal	2	no	6.424	6.628	EPSD	TCGA;ICGC;COSMIC	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	Q9NYF8	BCLAF1	P49841	GSK3B	S285	Y284C	284	Missense	proximal	-1	no	7.515	7.619	EPSD	TCGA;ICGC;COSMIC	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	Q9NYF8	BCLAF1	P49841	GSK3B	S285	N279I	279	Missense	distal	-6	no	7.515	7.454	EPSD	TCGA;ICGC;COSMIC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	Q9NYF8	BCLAF1	P49841	GSK3B	S285	R283Q	283	Missense	proximal	-2	no	7.515	7.585	EPSD	TCGA;ICGC;COSMIC	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	Q9NYF8	BCLAF1	P49841	GSK3B	S300	A306T	306	Missense	distal	6	no	8.714	8.718	EPSD	TCGA;ICGC;COSMIC;GDSC;CCLE	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	Q9NYF8	BCLAF1	P49841	GSK3B	S300	A302S	302	Missense	proximal	2	no	8.714	8.706	EPSD	TCGA;ICGC;COSMIC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	Q9NYF8	BCLAF1	P49841	GSK3B	S300	I295N	295	Missense	distal	-5	no	8.714	7.949	EPSD	TCGA;COSMIC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	Q9NYF8	BCLAF1	P49841	GSK3B	S300	P307S	307	Missense	distal	7	no	8.714	8.777	EPSD	TCGA;ICGC	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	Q9NYF8	BCLAF1	P49841	GSK3B	S300	P307L	307	Missense	distal	7	no	8.714	8.763	EPSD	TCGA;ICGC;COSMIC	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	Q9NYF8	BCLAF1	P49841	GSK3B	S300	P301L	301	Missense	proximal	1	no	8.714	5.853	EPSD	TCGA;COSMIC	6.007	Loss
CMGC_GSK_GSK3B_ST	Q9NYF8	BCLAF1	P49841	GSK3B	S300	S297P	297	Missense	distal	-3	no	8.714	8.597	EPSD	TCGA;ICGC;COSMIC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	Q9NYF8	BCLAF1	P49841	GSK3B	S300	H293N	293	Missense	distal	-7	no	8.714	8.702	EPSD	TCGA;ICGC;COSMIC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	Q9NYF8	BCLAF1	P49841	GSK3B	S315	S320W	320	Missense	distal	5	no	8.876	7.891	EPSD	TCGA;ICGC;COSMIC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	Q9NYF8	BCLAF1	P49841	GSK3B	S315	A310D	310	Missense	distal	-5	no	8.876	8.871	EPSD	TCGA;ICGC;COSMIC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	Q9NYF8	BCLAF1	P49841	GSK3B	S315	S315Y	315	Missense	central	0	yes	8.876	0.000	EPSD	TCGA;ICGC;COSMIC	6.007	Loss
CMGC_GSK_GSK3B_ST	Q9NYF8	BCLAF1	P49841	GSK3B	S315	S320L	320	Missense	distal	5	no	8.876	8.549	EPSD	TCGA;COSMIC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	Q9NYF8	BCLAF1	P49841	GSK3B	S315	R318C	318	Missense	distal	3	no	8.876	9.031	EPSD	TCGA;ICGC;COSMIC;GDSC	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	Q9NYF8	BCLAF1	P49841	GSK3B	S315	S320P	320	Missense	distal	5	no	8.876	9.830	EPSD	TCGA;COSMIC	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	Q9NYF8	BCLAF1	P49841	GSK3B	S315	D313Y	313	Missense	proximal	-2	no	8.876	8.572	EPSD	TCGA	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	Q9NYF8	BCLAF1	P49841	GSK3B	S319	S320P	320	Missense	proximal	1	no	2.620	6.465	EPSD	TCGA;COSMIC	6.007	Gain
CMGC_GSK_GSK3B_ST	Q9NYF8	BCLAF1	P49841	GSK3B	S385	Y383H	383	Missense	proximal	-2	no	6.855	7.069	EPSD	TCGA	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	Q9NYF8	BCLAF1	P49841	GSK3B	S385	K387R	387	Missense	proximal	2	no	6.855	6.920	EPSD	TCGA;COSMIC	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	Q9NYF8	BCLAF1	P49841	GSK3B	S385	G390E	390	Missense	distal	5	no	6.855	7.121	EPSD	TCGA;COSMIC	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	Q9NYF8	BCLAF1	P49841	GSK3B	S385	D386N	386	Missense	proximal	1	no	6.855	4.439	EPSD	TCGA;COSMIC	6.007	Loss
CMGC_GSK_GSK3B_ST	Q9NYF8	BCLAF1	P49841	GSK3B	S385	A380T	380	Missense	distal	-5	no	6.855	6.866	EPSD	TCGA	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	Q9NYF8	BCLAF1	P49841	GSK3B	S389	K393M	393	Missense	distal	4	no	5.564	6.532	EPSD	TCGA;COSMIC	6.007	Gain
CMGC_GSK_GSK3B_ST	Q9NYF8	BCLAF1	P49841	GSK3B	S427	S422R	422	Missense	distal	-5	no	5.806	6.504	EPSD	TCGA;COSMIC	6.007	Gain
CMGC_GSK_GSK3B_ST	Q9NYF8	BCLAF1	P49841	GSK3B	S427	H428Q	428	Missense	proximal	1	no	5.806	6.238	EPSD	TCGA;COSMIC	6.007	Gain
CMGC_GSK_GSK3B_ST	Q9NYF8	BCLAF1	P49841	GSK3B	S427	R429Q	429	Missense	proximal	2	no	5.806	6.011	EPSD	TCGA;COSMIC	6.007	Gain
CMGC_GSK_GSK3B_ST	Q9NYF8	BCLAF1	P49841	GSK3B	S485	I488M	488	Missense	distal	3	no	5.951	6.180	EPSD	TCGA;COSMIC	6.007	Gain
CMGC_GSK_GSK3B_ST	Q9NYF8	BCLAF1	P49841	GSK3B	S485	I488L	488	Missense	distal	3	no	5.951	6.071	EPSD	TCGA;COSMIC	6.007	Gain
CMGC_GSK_GSK3B_ST	Q9NYF8	BCLAF1	P49841	GSK3B	S485	V490L	490	Missense	distal	5	no	5.951	6.126	EPSD	TCGA;COSMIC	6.007	Gain
CMGC_GSK_GSK3B_ST	Q9NYF8	BCLAF1	P49841	GSK3B	S485	K479Q	479	Missense	distal	-6	no	5.951	6.009	EPSD	TCGA;COSMIC	6.007	Gain
CMGC_GSK_GSK3B_ST	Q9NYF8	BCLAF1	P49841	GSK3B	S485	K483T	483	Missense	proximal	-2	no	5.951	6.112	EPSD	TCGA;COSMIC	6.007	Gain
CMGC_GSK_GSK3B_ST	Q9NYF8	BCLAF1	P49841	GSK3B	S512	L515V	515	Missense	distal	3	no	6.049	6.141	EPSD	TCGA;COSMIC	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	Q9NYF8	BCLAF1	P49841	GSK3B	S512	D507Y	507	Missense	distal	-5	no	6.049	6.429	EPSD	TCGA;COSMIC	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	Q9NYF8	BCLAF1	P49841	GSK3B	S512	P513L	513	Missense	proximal	1	no	6.049	3.188	EPSD	TCGA;COSMIC	6.007	Loss
CMGC_GSK_GSK3B_ST	Q9NYF8	BCLAF1	P49841	GSK3B	S512	K517N	517	Missense	distal	5	no	6.049	6.287	EPSD	TCGA;GDSC;CCLE	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	Q9NYF8	BCLAF1	P49841	GSK3B	S531	R534K	534	Missense	distal	3	no	5.793	6.037	PhosphoSitePlus	TCGA;COSMIC	6.007	Gain
CMGC_GSK_GSK3B_ST	Q9NYF8	BCLAF1	P49841	GSK3B	S540	R544S	544	Missense	distal	4	no	5.388	8.425	EPSD	TCGA;COSMIC;GDSC;CCLE	6.007	Gain
CMGC_GSK_GSK3B_ST	Q9NYF8	BCLAF1	P49841	GSK3B	T644	E641Q	641	Missense	distal	-3	no	9.401	9.418	EPSD	TCGA;COSMIC	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	Q9NYF8	BCLAF1	P49841	GSK3B	T644	E641K	641	Missense	distal	-3	no	9.401	9.412	EPSD	TCGA	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	Q9NYF8	BCLAF1	P49841	GSK3B	T644	T639S	639	Missense	distal	-5	no	9.401	9.112	EPSD	TCGA;COSMIC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	Q9NYF8	BCLAF1	P49841	GSK3B	S658	R653S	653	Missense	distal	-5	no	8.786	8.089	EPSD	TCGA;COSMIC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	Q9NYF8	BCLAF1	P49841	GSK3B	S714	R708G	708	Missense	distal	-6	no	8.636	8.709	EPSD	TCGA;COSMIC	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	Q9NYF8	BCLAF1	P49841	GSK3B	S714	S718I	718	Missense	distal	4	no	8.636	5.314	EPSD	TCGA;COSMIC	6.007	Loss
CMGC_GSK_GSK3B_ST	Q9NYF8	BCLAF1	P49841	GSK3B	S714	G709E	709	Missense	distal	-5	no	8.636	8.600	EPSD	TCGA;COSMIC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	Q9NYF8	BCLAF1	P49841	GSK3B	S714	E707K	707	Missense	distal	-7	no	8.636	8.625	EPSD	TCGA;COSMIC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	Q9NYF8	BCLAF1	P49841	GSK3B	T726	P727T	727	Missense	proximal	1	no	7.054	3.863	EPSD	TCGA;COSMIC	6.007	Loss
CMGC_GSK_GSK3B_ST	Q9NYF8	BCLAF1	P49841	GSK3B	T726	E724K	724	Missense	proximal	-2	no	7.054	7.023	EPSD	TCGA;COSMIC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	Q9NYF8	BCLAF1	P49841	GSK3B	S749	D747Y	747	Missense	proximal	-2	no	7.933	7.629	EPSD	TCGA	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	Q9NYF8	BCLAF1	P49841	GSK3B	S749	S754F	754	Missense	distal	5	no	7.933	7.266	EPSD	TCGA;COSMIC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	Q9NYF8	BCLAF1	P49841	GSK3B	S749	S749F	749	Missense	central	0	yes	7.933	0.000	EPSD	TCGA;COSMIC	6.007	Loss
CMGC_GSK_GSK3B_ST	Q9NYF8	BCLAF1	P49841	GSK3B	S749	A756E	756	Missense	distal	7	no	7.933	7.624	EPSD	TCGA;COSMIC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	Q9NYF8	BCLAF1	P49841	GSK3B	S749	S753Y	753	Missense	distal	4	no	7.933	4.420	EPSD	TCGA;COSMIC	6.007	Loss
CMGC_GSK_GSK3B_ST	Q9NYF8	BCLAF1	P49841	GSK3B	S751	D747Y	747	Missense	distal	-4	no	7.694	7.494	EPSD	TCGA	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	Q9NYF8	BCLAF1	P49841	GSK3B	S751	S754F	754	Missense	distal	3	no	7.694	7.483	EPSD	TCGA;COSMIC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	Q9NYF8	BCLAF1	P49841	GSK3B	S751	S749F	749	Missense	proximal	-2	no	7.694	7.364	EPSD	TCGA;COSMIC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	Q9NYF8	BCLAF1	P49841	GSK3B	S751	A756E	756	Missense	distal	5	no	7.694	8.078	EPSD	TCGA;COSMIC	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	Q9NYF8	BCLAF1	P49841	GSK3B	S751	S753Y	753	Missense	proximal	2	no	7.694	7.462	EPSD	TCGA;COSMIC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	Q9NYF8	BCLAF1	P49841	GSK3B	S753	A756E	756	Missense	distal	3	no	5.879	6.196	EPSD	TCGA;COSMIC	6.007	Gain
CMGC_GSK_GSK3B_ST	Q9NYF8	BCLAF1	P49841	GSK3B	S755	S759F	759	Missense	distal	4	no	7.502	3.888	EPSD	TCGA;COSMIC	6.007	Loss
CMGC_GSK_GSK3B_ST	Q9NYF8	BCLAF1	P49841	GSK3B	S755	S754F	754	Missense	proximal	-1	no	7.502	7.372	EPSD	TCGA;COSMIC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	Q9NYF8	BCLAF1	P49841	GSK3B	S755	S749F	749	Missense	distal	-6	no	7.502	7.449	EPSD	TCGA;COSMIC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	Q9NYF8	BCLAF1	P49841	GSK3B	S755	A756E	756	Missense	proximal	1	no	7.502	7.401	EPSD	TCGA;COSMIC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	Q9NYF8	BCLAF1	P49841	GSK3B	S755	S753Y	753	Missense	proximal	-2	no	7.502	7.183	EPSD	TCGA;COSMIC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	Q9NYF8	BCLAF1	P49841	GSK3B	S757	S759F	759	Missense	proximal	2	no	8.512	8.168	EPSD	TCGA;COSMIC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	Q9NYF8	BCLAF1	P49841	GSK3B	S757	S754F	754	Missense	distal	-3	no	8.512	8.579	EPSD	TCGA;COSMIC	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	Q9NYF8	BCLAF1	P49841	GSK3B	S757	A756E	756	Missense	proximal	-1	no	8.512	8.656	EPSD	TCGA;COSMIC	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	Q9NYF8	BCLAF1	P49841	GSK3B	S757	S753Y	753	Missense	distal	-4	no	8.512	7.712	EPSD	TCGA;COSMIC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	Q9NYF8	BCLAF1	P49841	GSK3B	S757	R764L	764	Missense	distal	7	no	8.512	8.060	EPSD	TCGA;COSMIC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	Q9NYF8	BCLAF1	P49841	GSK3B	S757	S763F	763	Missense	distal	6	no	8.512	8.500	EPSD	TCGA;COSMIC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	Q9NYF8	BCLAF1	P49841	GSK3B	S759	S759F	759	Missense	central	0	yes	7.745	0.000	EPSD	TCGA;COSMIC	6.007	Loss
CMGC_GSK_GSK3B_ST	Q9NYF8	BCLAF1	P49841	GSK3B	S759	S754F	754	Missense	distal	-5	no	7.745	8.305	EPSD	TCGA;COSMIC	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	Q9NYF8	BCLAF1	P49841	GSK3B	S759	A756E	756	Missense	distal	-3	no	7.745	7.738	EPSD	TCGA;COSMIC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	Q9NYF8	BCLAF1	P49841	GSK3B	S759	S753Y	753	Missense	distal	-6	no	7.745	7.659	EPSD	TCGA;COSMIC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	Q9NYF8	BCLAF1	P49841	GSK3B	S759	R764L	764	Missense	distal	5	no	7.745	7.103	EPSD	TCGA;COSMIC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	Q9NYF8	BCLAF1	P49841	GSK3B	S759	E765K	765	Missense	distal	6	no	7.745	7.746	EPSD	TCGA;COSMIC	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	Q9NYF8	BCLAF1	P49841	GSK3B	S759	S763F	763	Missense	distal	4	no	7.745	4.131	EPSD	TCGA;COSMIC	6.007	Loss
CMGC_GSK_GSK3B_ST	Q9NYF8	BCLAF1	P49841	GSK3B	S760	S759F	759	Missense	proximal	-1	no	7.612	7.482	EPSD	TCGA;COSMIC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	Q9NYF8	BCLAF1	P49841	GSK3B	S760	S754F	754	Missense	distal	-6	no	7.612	7.559	EPSD	TCGA;COSMIC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	Q9NYF8	BCLAF1	P49841	GSK3B	S760	A756E	756	Missense	distal	-4	no	7.612	8.175	EPSD	TCGA;COSMIC	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	Q9NYF8	BCLAF1	P49841	GSK3B	S760	S753Y	753	Missense	distal	-7	no	7.612	7.640	EPSD	TCGA;COSMIC	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	Q9NYF8	BCLAF1	P49841	GSK3B	S760	R764L	764	Missense	distal	4	no	7.612	7.932	EPSD	TCGA;COSMIC	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	Q9NYF8	BCLAF1	P49841	GSK3B	S760	E765K	765	Missense	distal	5	no	7.612	6.745	EPSD	TCGA;COSMIC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	Q9NYF8	BCLAF1	P49841	GSK3B	S760	S763F	763	Missense	distal	3	no	7.612	7.401	EPSD	TCGA;COSMIC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	Q9NYF8	BCLAF1	P49841	GSK3B	S881	P885S	885	Missense	distal	4	no	4.254	7.225	EPSD	TCGA;COSMIC	6.007	Gain
CMGC_GSK_GSK3B_ST	Q9NYF8	BCLAF1	P49841	GSK3B	S884	W887L	887	Missense	distal	3	no	8.318	8.130	EPSD	TCGA;COSMIC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	Q9NYF8	BCLAF1	P49841	GSK3B	S884	G882V	882	Missense	proximal	-2	no	8.318	8.403	EPSD	TCGA;COSMIC	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	Q9NYF8	BCLAF1	P49841	GSK3B	S884	S881L	881	Missense	distal	-3	no	8.318	8.328	EPSD	TCGA;COSMIC	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	Q9NYF8	BCLAF1	P49841	GSK3B	S884	S883C	883	Missense	proximal	-1	no	8.318	8.282	EPSD	TCGA;COSMIC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	Q9NYF8	BCLAF1	P49841	GSK3B	S884	W887R	887	Missense	distal	3	no	8.318	8.060	EPSD	TCGA;COSMIC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	Q9NYF8	BCLAF1	P49841	GSK3B	S884	P885S	885	Missense	proximal	1	no	8.318	4.474	EPSD	TCGA;COSMIC	6.007	Loss
CMGC_GSK_GSK3B_ST	Q9NYF8	BCLAF1	P49841	GSK3B	S884	H889Y	889	Missense	distal	5	no	8.318	7.992	EPSD	TCGA;COSMIC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	Q9NYF8	BCLAF1	P49841	GSK3B	S884	N877H	877	Missense	distal	-7	no	8.318	8.330	EPSD	TCGA;COSMIC	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	Q9NYF8	BCLAF1	P49841	GSK3B	S884	K880Q	880	Missense	distal	-4	no	8.318	8.354	EPSD	TCGA;COSMIC	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	O75030	MITF	P49841	GSK3B	S176	A177T	177	Missense	proximal	1	no	6.901	7.442	EPSD	TCGA;ICGC;COSMIC	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	O75030	MITF	P49841	GSK3B	S176	V172L	172	Missense	distal	-4	no	6.901	6.784	EPSD	TCGA;ICGC;COSMIC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	O75030	MITF	P49841	GSK3B	S176	P178L	178	Missense	proximal	2	no	6.901	6.517	EPSD	TCGA;ICGC;COSMIC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	O75030	MITF	P49841	GSK3B	S176	P171L	171	Missense	distal	-5	no	6.901	7.167	EPSD	TCGA;ICGC;COSMIC;CCLE	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	O75030	MITF	P49841	GSK3B	S180	A177T	177	Missense	distal	-3	no	8.658	8.663	EPSD	TCGA;ICGC;COSMIC	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	O75030	MITF	P49841	GSK3B	S180	T186M	186	Missense	distal	6	no	8.658	8.651	EPSD	TCGA;ICGC;COSMIC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	O75030	MITF	P49841	GSK3B	S180	P178L	178	Missense	proximal	-2	no	8.658	8.328	EPSD	TCGA;ICGC;COSMIC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	P48436	SOX9	P49841	GSK3B	S19	G17S	17	Missense	proximal	-2	no	9.328	9.445	EPSD	TCGA;ICGC;COSMIC	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	P48436	SOX9	P49841	GSK3B	S23	G17S	17	Missense	distal	-6	no	9.576	9.560	EPSD	TCGA;ICGC;COSMIC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	P48436	SOX9	P49841	GSK3B	S33	G40R	40	Missense	distal	7	no	8.960	9.378	EPSD	TCGA;ICGC;COSMIC	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	P48436	SOX9	P49841	GSK3B	S33	A31V	31	Missense	proximal	-2	no	8.960	9.262	EPSD	TCGA;ICGC;COSMIC	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	P48436	SOX9	P49841	GSK3B	S33	P36S	36	Missense	distal	3	no	8.960	8.942	EPSD	TCGA;ICGC;COSMIC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	P48436	SOX9	P49841	GSK3B	S37	G40R	40	Missense	distal	3	no	8.222	7.808	EPSD	TCGA;ICGC;COSMIC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	P48436	SOX9	P49841	GSK3B	S37	A31V	31	Missense	distal	-6	no	8.222	8.144	EPSD	TCGA;ICGC;COSMIC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	P48436	SOX9	P49841	GSK3B	S37	P36S	36	Missense	proximal	-1	no	8.222	8.166	EPSD	TCGA;ICGC;COSMIC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	P48436	SOX9	P49841	GSK3B	S211	M218I	218	Missense	distal	7	no	8.253	8.220	EPSD	TCGA;ICGC;COSMIC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	P48436	SOX9	P49841	GSK3B	S211	S214P	214	Missense	distal	3	no	8.253	8.271	EPSD	TCGA;ICGC;COSMIC	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	P48436	SOX9	P49841	GSK3B	S211	A206V	206	Missense	distal	-5	no	8.253	8.555	EPSD	TCGA;ICGC	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	P48436	SOX9	P49841	GSK3B	S215	M218I	218	Missense	distal	3	no	7.687	7.458	EPSD	TCGA;ICGC;COSMIC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	P48436	SOX9	P49841	GSK3B	S215	S214P	214	Missense	proximal	-1	no	7.687	7.744	EPSD	TCGA;ICGC;COSMIC	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	P48436	SOX9	P49841	GSK3B	S219	M218I	218	Missense	proximal	-1	no	6.894	6.795	EPSD	TCGA;ICGC;COSMIC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	P48436	SOX9	P49841	GSK3B	S219	S214P	214	Missense	distal	-5	no	6.894	6.738	EPSD	TCGA;ICGC;COSMIC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	P48436	SOX9	P49841	GSK3B	S223	M218I	218	Missense	distal	-5	no	8.263	8.434	EPSD	TCGA;ICGC;COSMIC	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	P48436	SOX9	P49841	GSK3B	T236	P235A	235	Missense	proximal	-1	no	8.814	8.603	PhosphoSitePlus	TCGA;ICGC;COSMIC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	P48436	SOX9	P49841	GSK3B	T239	P235A	235	Missense	distal	-4	no	6.312	5.716	EPSD	TCGA;ICGC;COSMIC	6.007	Loss
CMGC_GSK_GSK3B_ST	P48436	SOX9	P49841	GSK3B	S488	A481G	481	Missense	distal	-7	no	6.552	6.527	EPSD	TCGA;ICGC;COSMIC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	P48436	SOX9	P49841	GSK3B	S488	S484F	484	Missense	distal	-4	no	6.552	5.398	EPSD	TCGA;ICGC;COSMIC	6.007	Loss
CMGC_GSK_GSK3B_ST	P48436	SOX9	P49841	GSK3B	S488	S494N	494	Missense	distal	6	no	6.552	6.546	EPSD	TCGA;ICGC;COSMIC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	P48436	SOX9	P49841	GSK3B	S488	P490L	490	Missense	proximal	2	no	6.552	6.168	EPSD	TCGA;ICGC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	P48436	SOX9	P49841	GSK3B	S488	S484A	484	Missense	distal	-4	no	6.552	5.392	EPSD	TCGA;ICGC;COSMIC	6.007	Loss
CMGC_GSK_GSK3B_ST	P48436	SOX9	P49841	GSK3B	S494	H497N	497	Missense	distal	3	no	7.457	7.533	EPSD	TCGA;ICGC;COSMIC	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	P48436	SOX9	P49841	GSK3B	S494	S494N	494	Missense	central	0	yes	7.457	0.000	EPSD	TCGA;ICGC;COSMIC	6.007	Loss
CMGC_GSK_GSK3B_ST	P48436	SOX9	P49841	GSK3B	S494	P490L	490	Missense	distal	-4	no	7.457	6.670	EPSD	TCGA;ICGC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	P06401	PGR	P49841	GSK3B	S88	A86T	86	Missense	proximal	-2	no	5.920	6.282	EPSD	TCGA;ICGC;COSMIC;GDSC;CCLE	6.007	Gain
CMGC_GSK_GSK3B_ST	P06401	PGR	P49841	GSK3B	S102	G109R	109	Missense	distal	7	no	7.295	7.713	EPSD	TCGA;ICGC;COSMIC	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	P06401	PGR	P49841	GSK3B	S102	S102I	102	Missense	central	0	yes	7.295	0.000	EPSD	TCGA;ICGC	6.007	Loss
CMGC_GSK_GSK3B_ST	P06401	PGR	P49841	GSK3B	S102	S101C	101	Missense	proximal	-1	no	7.295	7.259	EPSD	TCGA;ICGC;COSMIC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	P06401	PGR	P49841	GSK3B	S102	S108I	108	Missense	distal	6	no	7.295	7.294	EPSD	TCGA;ICGC;COSMIC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	P06401	PGR	P49841	GSK3B	S213	A218V	218	Missense	distal	5	no	6.936	6.509	EPSD	TCGA;ICGC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	P06401	PGR	P49841	GSK3B	S273	S276L	276	Missense	distal	3	no	6.161	5.860	EPSD	TCGA;ICGC;COSMIC;CCLE	6.007	Loss
CMGC_GSK_GSK3B_ST	P06401	PGR	P49841	GSK3B	S273	R274H	274	Missense	proximal	1	no	6.161	4.780	EPSD	TCGA;ICGC;COSMIC	6.007	Loss
CMGC_GSK_GSK3B_ST	P06401	PGR	P49841	GSK3B	S294	T299A	299	Missense	distal	5	no	9.431	9.379	EPSD	TCGA;ICGC;COSMIC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	P06401	PGR	P49841	GSK3B	S294	A287E	287	Missense	distal	-7	no	9.431	9.442	EPSD	TCGA;ICGC;COSMIC	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	P06401	PGR	P49841	GSK3B	S294	R293C	293	Missense	proximal	-1	no	9.431	9.533	EPSD	TCGA;ICGC;COSMIC	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	P06401	PGR	P49841	GSK3B	S345	F339Y	339	Missense	distal	-6	no	9.402	9.369	EPSD	TCGA;ICGC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	P06401	PGR	P49841	GSK3B	T351	A354T	354	Missense	distal	3	no	7.159	7.463	EPSD	TCGA;ICGC;COSMIC;GDSC;CCLE	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	P06401	PGR	P49841	GSK3B	S554	Q556H	556	Missense	proximal	2	no	10.722	10.174	EPSD	TCGA;ICGC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	P06401	PGR	P49841	GSK3B	S554	S552N	552	Missense	proximal	-2	no	10.722	10.494	EPSD	TCGA;ICGC;COSMIC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	P06401	PGR	P49841	GSK3B	S666	S666N	666	Missense	central	0	yes	6.451	0.000	EPSD	TCGA;ICGC;COSMIC	6.007	Loss
CMGC_GSK_GSK3B_ST	P06401	PGR	P49841	GSK3B	S666	V662I	662	Missense	distal	-4	no	6.451	5.202	EPSD	TCGA;ICGC;COSMIC;GDSC	6.007	Loss
CMGC_GSK_GSK3B_ST	P06401	PGR	P49841	GSK3B	S666	A668V	668	Missense	proximal	2	no	6.451	6.175	EPSD	TCGA;ICGC;COSMIC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	P06401	PGR	P49841	GSK3B	S666	R672T	672	Missense	distal	6	no	6.451	6.458	EPSD	TCGA;ICGC;COSMIC	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	P06401	PGR	P49841	GSK3B	S666	P663S	663	Missense	distal	-3	no	6.451	6.568	EPSD	TCGA;ICGC;COSMIC	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	P06401	PGR	P49841	GSK3B	S666	R672I	672	Missense	distal	6	no	6.451	6.456	EPSD	TCGA;ICGC;COSMIC	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	P06401	PGR	P49841	GSK3B	S676	R672T	672	Missense	distal	-4	no	5.178	6.029	EPSD	TCGA;ICGC;COSMIC	6.007	Gain
CMGC_GSK_GSK3B_ST	Q9NRD5	PICK1	P49841	GSK3B	S411	G404W	404	Missense	distal	-7	no	6.750	6.781	EPSD	TCGA;ICGC;COSMIC	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	O75952	CABYR	P49841	GSK3B	T75	E72D	72	Missense	distal	-3	no	7.069	7.102	EPSD	TCGA;ICGC;COSMIC	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	O75952	CABYR	P49841	GSK3B	T75	E68K	68	Missense	distal	-7	no	7.069	7.058	EPSD	TCGA;ICGC;COSMIC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	O75952	CABYR	P49841	GSK3B	T75	K78N	78	Missense	distal	3	no	7.069	7.244	EPSD	TCGA;ICGC;COSMIC	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	O75952	CABYR	P49841	GSK3B	T75	E68D	68	Missense	distal	-7	no	7.069	7.039	EPSD	TCGA;ICGC;COSMIC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	O75952	CABYR	P49841	GSK3B	T120	S124L	124	Missense	distal	4	no	7.066	4.348	EPSD	TCGA;ICGC;COSMIC	6.007	Loss
CMGC_GSK_GSK3B_ST	O75952	CABYR	P49841	GSK3B	S142	E135K	135	Missense	distal	-7	no	7.933	7.922	EPSD	TCGA;ICGC;COSMIC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	O75952	CABYR	P49841	GSK3B	T150	P152T	152	Missense	proximal	2	no	7.591	7.273	EPSD	TCGA;ICGC;COSMIC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	O75952	CABYR	P49841	GSK3B	T150	P156L	156	Missense	distal	6	no	7.591	7.584	EPSD	TCGA;ICGC;COSMIC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	O75952	CABYR	P49841	GSK3B	T151	P152T	152	Missense	proximal	1	no	11.855	8.664	PhosphoSitePlus;EPSD	TCGA;ICGC;COSMIC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	O75952	CABYR	P49841	GSK3B	T151	P156L	156	Missense	distal	5	no	11.855	10.574	PhosphoSitePlus;EPSD	TCGA;ICGC;COSMIC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	O75952	CABYR	P49841	GSK3B	S155	P152T	152	Missense	distal	-3	no	10.347	10.489	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	O75952	CABYR	P49841	GSK3B	S155	P156L	156	Missense	proximal	1	no	10.347	7.487	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	O75952	CABYR	P49841	GSK3B	S184	S185R	185	Missense	proximal	1	no	5.317	6.842	EPSD	TCGA;ICGC;COSMIC	6.007	Gain
CMGC_GSK_GSK3B_ST	Q01518	CAP1	P49841	GSK3B	S34	K37Q	37	Missense	distal	3	no	9.154	9.243	EPSD	TCGA;ICGC	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	Q01518	CAP1	P49841	GSK3B	S34	R29G	29	Missense	distal	-5	no	9.154	8.923	EPSD	TCGA;ICGC;COSMIC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	Q01518	CAP1	P49841	GSK3B	S34	S36L	36	Missense	proximal	2	no	9.154	9.214	EPSD	TCGA;ICGC;COSMIC	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	Q01518	CAP1	P49841	GSK3B	S308	R313Q	313	Missense	distal	5	no	6.186	5.847	EPSD;PhosphoSitePlus	TCGA;COSMIC	6.007	Loss
CMGC_GSK_GSK3B_ST	Q01518	CAP1	P49841	GSK3B	S310	R313Q	313	Missense	distal	3	no	7.057	7.390	PhosphoSitePlus;EPSD	TCGA;COSMIC	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	Q01518	CAP1	P49841	GSK3B	T359	I363S	363	Missense	distal	4	no	3.504	6.826	EPSD	TCGA;ICGC;COSMIC	6.007	Gain
CMGC_GSK_GSK3B_ST	P04150	NR3C1	P49841	GSK3B	T8	P9H	9	Missense	proximal	1	no	6.709	3.009	EPSD	TCGA;COSMIC	6.007	Loss
CMGC_GSK_GSK3B_ST	P04150	NR3C1	P49841	GSK3B	S45	A51T	51	Missense	distal	6	no	6.427	6.431	EPSD	TCGA;ICGC;COSMIC	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	P04150	NR3C1	P49841	GSK3B	S45	S42Y	42	Missense	distal	-3	no	6.427	6.568	EPSD	TCGA;ICGC;COSMIC	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	P04150	NR3C1	P49841	GSK3B	S79	L84R	84	Missense	distal	5	no	6.608	7.251	EPSD	TCGA;ICGC;COSMIC	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	P04150	NR3C1	P49841	GSK3B	S79	S83L	83	Missense	distal	4	no	6.608	3.891	EPSD	TCGA;ICGC;COSMIC	6.007	Loss
CMGC_GSK_GSK3B_ST	P04150	NR3C1	P49841	GSK3B	S79	A73V	73	Missense	distal	-6	no	6.608	6.530	EPSD	TCGA;ICGC;COSMIC;GDSC;CCLE	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	P04150	NR3C1	P49841	GSK3B	S79	S79F	79	Missense	central	0	yes	6.608	0.000	EPSD	TCGA;ICGC;COSMIC	6.007	Loss
CMGC_GSK_GSK3B_ST	P04150	NR3C1	P49841	GSK3B	S79	P76S	76	Missense	distal	-3	no	6.608	6.725	EPSD	TCGA	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	P04150	NR3C1	P49841	GSK3B	S113	S114L	114	Missense	proximal	1	no	5.062	6.046	EPSD	TCGA;ICGC;COSMIC	6.007	Gain
CMGC_GSK_GSK3B_ST	P04150	NR3C1	P49841	GSK3B	S141	P136L	136	Missense	distal	-5	no	6.393	6.659	EPSD	TCGA;ICGC;COSMIC	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	P04150	NR3C1	P49841	GSK3B	S141	K140N	140	Missense	proximal	-1	no	6.393	6.400	EPSD	TCGA;ICGC;COSMIC	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	P04150	NR3C1	P49841	GSK3B	S211	P212H	212	Missense	proximal	1	no	9.880	6.179	EPSD	TCGA;ICGC;COSMIC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	P04150	NR3C1	P49841	GSK3B	S226	N222T	222	Missense	distal	-4	no	6.132	7.094	EPSD	TCGA;ICGC;COSMIC	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	P04150	NR3C1	P49841	GSK3B	S226	A229V	229	Missense	distal	3	no	6.132	6.261	EPSD	TCGA;ICGC;COSMIC	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	P04150	NR3C1	P49841	GSK3B	S226	G230R	230	Missense	distal	4	no	6.132	6.337	EPSD	TCGA;ICGC	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	P04150	NR3C1	P49841	GSK3B	S226	I219L	219	Missense	distal	-7	no	6.132	6.104	EPSD	TCGA;ICGC;COSMIC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	P04150	NR3C1	P49841	GSK3B	S395	S395I	395	Missense	central	0	yes	7.593	0.000	EPSD	TCGA;ICGC	6.007	Loss
CMGC_GSK_GSK3B_ST	P04150	NR3C1	P49841	GSK3B	S403	S404Y	404	Missense	proximal	1	no	5.669	6.195	EPSD	TCGA;ICGC	6.007	Gain
CMGC_GSK_GSK3B_ST	P04150	NR3C1	P49841	GSK3B	S404	S404Y	404	Missense	central	0	yes	11.548	0.000	PhosphoSitePlus	TCGA;ICGC	6.007	Loss
CMGC_GSK_GSK3B_ST	P04150	NR3C1	P49841	GSK3B	S407	S404Y	404	Missense	distal	-3	no	6.996	7.137	EPSD	TCGA;ICGC	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	P04150	NR3C1	P49841	GSK3B	S408	S404Y	404	Missense	distal	-4	no	6.121	5.321	EPSD	TCGA;ICGC	6.007	Loss
CMGC_GSK_GSK3B_ST	P04150	NR3C1	P49841	GSK3B	S409	S404Y	404	Missense	distal	-5	no	6.328	6.980	EPSD	TCGA;ICGC	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	P04150	NR3C1	P49841	GSK3B	S409	P416Q	416	Missense	distal	7	no	6.328	6.481	EPSD	TCGA;ICGC;COSMIC	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	Q9NP62	GCM1	P49841	GSK3B	S182	V179I	179	Missense	distal	-3	no	6.817	6.763	EPSD	TCGA;ICGC;COSMIC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	Q9NP62	GCM1	P49841	GSK3B	S182	G185E	185	Missense	distal	3	no	6.817	6.754	EPSD	TCGA;ICGC;COSMIC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	Q9NP62	GCM1	P49841	GSK3B	S182	K184N	184	Missense	proximal	2	no	6.817	6.332	EPSD	TCGA;ICGC;COSMIC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	Q9NP62	GCM1	P49841	GSK3B	S322	N315S	315	Missense	distal	-7	no	7.677	7.671	PhosphoSitePlus	TCGA;ICGC;COSMIC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	Q9NP62	GCM1	P49841	GSK3B	S322	F327L	327	Missense	distal	5	no	7.677	8.018	PhosphoSitePlus	TCGA;COSMIC	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	Q9NP62	GCM1	P49841	GSK3B	S322	S322N	322	Missense	central	0	yes	7.677	0.000	PhosphoSitePlus	TCGA;ICGC;COSMIC	6.007	Loss
CMGC_GSK_GSK3B_ST	Q9NP62	GCM1	P49841	GSK3B	S326	F327L	327	Missense	proximal	1	no	6.523	7.894	EPSD	TCGA;COSMIC	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	Q9NP62	GCM1	P49841	GSK3B	S326	S322N	322	Missense	distal	-4	no	6.523	5.226	EPSD	TCGA;ICGC;COSMIC	6.007	Loss
CMGC_GSK_GSK3B_ST	Q00613	HSF1	P49841	GSK3B	S123	E128K	128	Missense	distal	5	no	8.317	7.450	EPSD	TCGA;COSMIC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	Q00613	HSF1	P49841	GSK3B	S123	I130V	130	Missense	distal	7	no	8.317	8.407	EPSD	TCGA;COSMIC	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	Q00613	HSF1	P49841	GSK3B	S123	L125M	125	Missense	proximal	2	no	8.317	7.686	EPSD	TCGA;COSMIC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	Q00613	HSF1	P49841	GSK3B	T124	E128K	128	Missense	distal	4	no	6.591	5.409	EPSD	TCGA;COSMIC	6.007	Loss
CMGC_GSK_GSK3B_ST	Q00613	HSF1	P49841	GSK3B	T124	I130V	130	Missense	distal	6	no	6.591	6.581	EPSD	TCGA;COSMIC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	Q00613	HSF1	P49841	GSK3B	T124	L125M	125	Missense	proximal	1	no	6.591	5.865	EPSD	TCGA;COSMIC	6.007	Loss
CMGC_GSK_GSK3B_ST	Q00613	HSF1	P49841	GSK3B	S244	S250C	250	Missense	distal	6	no	9.276	9.263	EPSD	TCGA;COSMIC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	Q00613	HSF1	P49841	GSK3B	S275	P276L	276	Missense	proximal	1	no	10.301	7.440	EPSD	TCGA;COSMIC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	Q00613	HSF1	P49841	GSK3B	S275	M277V	277	Missense	proximal	2	no	10.301	10.603	EPSD	TCGA;COSMIC	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	Q00613	HSF1	P49841	GSK3B	S279	P276L	276	Missense	distal	-3	no	9.764	9.891	EPSD	TCGA;COSMIC	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	Q00613	HSF1	P49841	GSK3B	S279	E286K	286	Missense	distal	7	no	9.764	9.656	EPSD	TCGA;COSMIC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	Q00613	HSF1	P49841	GSK3B	S279	M277V	277	Missense	proximal	-2	no	9.764	10.063	EPSD	TCGA;COSMIC	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	Q00613	HSF1	P49841	GSK3B	S292	R296C	296	Missense	distal	4	no	7.295	4.199	EPSD	TCGA;COSMIC	6.007	Loss
CMGC_GSK_GSK3B_ST	Q00613	HSF1	P49841	GSK3B	S292	P288L	288	Missense	distal	-4	no	7.295	6.508	EPSD	TCGA;COSMIC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	Q00613	HSF1	P49841	GSK3B	S292	E286K	286	Missense	distal	-6	no	7.295	7.293	EPSD	TCGA;COSMIC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	Q00613	HSF1	P49841	GSK3B	S303	E300Q	300	Missense	distal	-3	no	13.157	13.174	PhosphoSitePlus	TCGA	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	Q00613	HSF1	P49841	GSK3B	S303	R296C	296	Missense	distal	-7	no	13.157	13.161	PhosphoSitePlus	TCGA;COSMIC	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	Q00613	HSF1	P49841	GSK3B	S307	E300Q	300	Missense	distal	-7	no	8.879	8.861	EPSD	TCGA	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	Q00613	HSF1	P49841	GSK3B	S314	R317H	317	Missense	distal	3	no	6.674	7.016	EPSD	TCGA;COSMIC	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	Q00613	HSF1	P49841	GSK3B	S314	S320F	320	Missense	distal	6	no	6.674	6.662	EPSD	TCGA;COSMIC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	Q00613	HSF1	P49841	GSK3B	S326	D332Y	332	Missense	distal	6	no	6.572	6.573	EPSD	TCGA;COSMIC	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	Q00613	HSF1	P49841	GSK3B	S326	T323I	323	Missense	distal	-3	no	6.572	6.660	EPSD	TCGA;COSMIC	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	Q00613	HSF1	P49841	GSK3B	S326	S320F	320	Missense	distal	-6	no	6.572	6.518	EPSD	TCGA;COSMIC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	Q00613	HSF1	P49841	GSK3B	S326	A329T	329	Missense	distal	3	no	6.572	6.876	EPSD	TCGA;COSMIC	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	Q00613	HSF1	P49841	GSK3B	S326	S333F	333	Missense	distal	7	no	6.572	6.649	EPSD	TCGA;COSMIC	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	Q00613	HSF1	P49841	GSK3B	S326	P327L	327	Missense	proximal	1	no	6.572	3.711	EPSD	TCGA	6.007	Loss
CMGC_GSK_GSK3B_ST	Q00613	HSF1	P49841	GSK3B	S344	A351T	351	Missense	distal	7	no	6.021	5.615	EPSD	TCGA;COSMIC	6.007	Loss
CMGC_GSK_GSK3B_ST	Q00613	HSF1	P49841	GSK3B	S344	E339G	339	Missense	distal	-5	no	6.021	6.057	EPSD	TCGA;COSMIC	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	Q00613	HSF1	P49841	GSK3B	S363	P364S	364	Missense	proximal	1	no	11.390	7.545	EPSD	TCGA;COSMIC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	Q00613	HSF1	P49841	GSK3B	S419	P420L	420	Missense	proximal	1	no	7.800	4.939	EPSD	TCGA;ICGC;COSMIC	6.007	Loss
CMGC_GSK_GSK3B_ST	Q00613	HSF1	P49841	GSK3B	S419	P425S	425	Missense	distal	6	no	7.800	7.798	EPSD	TCGA;ICGC;COSMIC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	Q00613	HSF1	P49841	GSK3B	S444	E441K	441	Missense	distal	-3	no	8.709	8.719	EPSD	TCGA;COSMIC	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	Q00613	HSF1	P49841	GSK3B	S457	E453K	453	Missense	distal	-4	no	6.497	6.230	EPSD	TCGA;COSMIC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	Q00613	HSF1	P49841	GSK3B	S458	E453K	453	Missense	distal	-5	no	6.430	6.200	EPSD	TCGA;COSMIC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	Q9HB09	BCL2L12	P49841	GSK3B	S156	R160C	160	Missense	distal	4	no	6.428	3.333	PhosphoSitePlus	TCGA;ICGC;COSMIC;GDSC	6.007	Loss
CMGC_GSK_GSK3B_ST	Q9HB09	BCL2L12	P49841	GSK3B	S156	S156C	156	Missense	central	0	yes	6.428	0.000	PhosphoSitePlus	TCGA;ICGC;COSMIC	6.007	Loss
CMGC_GSK_GSK3B_ST	Q9HB09	BCL2L12	P49841	GSK3B	S156	S149C	149	Missense	distal	-7	no	6.428	6.450	PhosphoSitePlus	TCGA;ICGC;COSMIC	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	Q9HB09	BCL2L12	P49841	GSK3B	T171	P167T	167	Missense	distal	-4	no	7.344	7.572	EPSD	TCGA;ICGC;COSMIC	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	Q9HB09	BCL2L12	P49841	GSK3B	T171	A176D	176	Missense	distal	5	no	7.344	7.525	EPSD	TCGA;COSMIC	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	Q9HB09	BCL2L12	P49841	GSK3B	S192	P196L	196	Missense	distal	4	no	8.491	8.744	EPSD	TCGA;COSMIC	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	Q9HB09	BCL2L12	P49841	GSK3B	S192	P193L	193	Missense	proximal	1	no	8.491	5.630	EPSD	TCGA;ICGC;COSMIC	6.007	Loss
CMGC_GSK_GSK3B_ST	Q9HB09	BCL2L12	P49841	GSK3B	S192	P193S	193	Missense	proximal	1	no	8.491	4.646	EPSD	TCGA;COSMIC	6.007	Loss
CMGC_GSK_GSK3B_ST	Q9HB09	BCL2L12	P49841	GSK3B	S195	P196L	196	Missense	proximal	1	no	7.349	4.488	EPSD	TCGA;COSMIC	6.007	Loss
CMGC_GSK_GSK3B_ST	Q9HB09	BCL2L12	P49841	GSK3B	S195	P193L	193	Missense	proximal	-2	no	7.349	7.018	EPSD	TCGA;ICGC;COSMIC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	Q9HB09	BCL2L12	P49841	GSK3B	S195	P193S	193	Missense	proximal	-2	no	7.349	7.092	EPSD	TCGA;COSMIC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	O75581	LRP6	P49841	GSK3B	T420	R415Q	415	Missense	distal	-5	no	6.201	5.647	EPSD	TCGA;ICGC;COSMIC	6.007	Loss
CMGC_GSK_GSK3B_ST	O75581	LRP6	P49841	GSK3B	T420	N416S	416	Missense	distal	-4	no	6.201	7.499	EPSD	TCGA;ICGC;COSMIC	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	O75581	LRP6	P49841	GSK3B	T420	L417I	417	Missense	distal	-3	no	6.201	6.305	EPSD	TCGA;ICGC;COSMIC	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	O75581	LRP6	P49841	GSK3B	T1001	G996D	996	Missense	distal	-5	no	8.027	7.834	EPSD	TCGA;ICGC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	O75581	LRP6	P49841	GSK3B	S1431	S1435T	1435	Missense	distal	4	no	7.572	6.703	EPSD	TCGA	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	O75581	LRP6	P49841	GSK3B	S1431	S1431Y	1431	Missense	central	0	yes	7.572	0.000	EPSD	TCGA;COSMIC	6.007	Loss
CMGC_GSK_GSK3B_ST	O75581	LRP6	P49841	GSK3B	S1431	S1431F	1431	Missense	central	0	yes	7.572	0.000	EPSD	TCGA;COSMIC	6.007	Loss
CMGC_GSK_GSK3B_ST	O75581	LRP6	P49841	GSK3B	S1431	L1432V	1432	Missense	proximal	1	no	7.572	7.442	EPSD	TCGA;COSMIC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	O75581	LRP6	P49841	GSK3B	S1431	S1433A	1433	Missense	proximal	2	no	7.572	7.580	EPSD	TCGA	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	O75581	LRP6	P49841	GSK3B	S1435	S1431Y	1431	Missense	distal	-4	no	8.170	7.369	EPSD	TCGA;COSMIC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	O75581	LRP6	P49841	GSK3B	S1435	S1431F	1431	Missense	distal	-4	no	8.170	7.016	EPSD	TCGA;COSMIC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	O75581	LRP6	P49841	GSK3B	S1435	R1441Q	1441	Missense	distal	6	no	8.170	8.171	EPSD	TCGA;COSMIC	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	O75581	LRP6	P49841	GSK3B	S1435	L1432V	1432	Missense	distal	-3	no	8.170	8.328	EPSD	TCGA;COSMIC	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	O75581	LRP6	P49841	GSK3B	S1435	S1433A	1433	Missense	proximal	-2	no	8.170	7.835	EPSD	TCGA	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	O75581	LRP6	P49841	GSK3B	S1440	S1435T	1435	Missense	distal	-5	no	6.938	7.228	EPSD	TCGA	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	O75581	LRP6	P49841	GSK3B	S1440	S1447C	1447	Missense	distal	7	no	6.938	7.331	EPSD	TCGA;COSMIC	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	O75581	LRP6	P49841	GSK3B	S1440	R1441Q	1441	Missense	proximal	1	no	6.938	5.990	EPSD	TCGA;COSMIC	6.007	Loss
CMGC_GSK_GSK3B_ST	O75581	LRP6	P49841	GSK3B	S1440	S1433A	1433	Missense	distal	-7	no	6.938	6.961	EPSD	TCGA	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	O75581	LRP6	P49841	GSK3B	S1440	M1445I	1445	Missense	distal	5	no	6.938	6.411	EPSD	TCGA;COSMIC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	O75581	LRP6	P49841	GSK3B	S1444	S1447C	1447	Missense	distal	3	no	6.997	6.781	EPSD	TCGA;COSMIC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	O75581	LRP6	P49841	GSK3B	S1444	R1441Q	1441	Missense	distal	-3	no	6.997	6.858	EPSD	TCGA;COSMIC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	O75581	LRP6	P49841	GSK3B	S1444	M1445I	1445	Missense	proximal	1	no	6.997	6.702	EPSD	TCGA;COSMIC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	O75581	LRP6	P49841	GSK3B	S1508	G1503E	1503	Missense	distal	-5	no	6.755	6.720	EPSD	TCGA;COSMIC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	O75581	LRP6	P49841	GSK3B	S1508	S1505Y	1505	Missense	distal	-3	no	6.755	6.895	EPSD	TCGA	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	O75581	LRP6	P49841	GSK3B	S1510	S1505Y	1505	Missense	distal	-5	no	5.781	6.433	EPSD	TCGA	6.007	Gain
CMGC_GSK_GSK3B_ST	O75581	LRP6	P49841	GSK3B	T1530	R1523W	1523	Missense	distal	-7	no	7.392	7.402	EPSD	TCGA;COSMIC	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	O75581	LRP6	P49841	GSK3B	T1530	H1524Q	1524	Missense	distal	-6	no	7.392	7.422	EPSD	TCGA;COSMIC	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	O75581	LRP6	P49841	GSK3B	T1530	H1524Y	1524	Missense	distal	-6	no	7.392	7.340	EPSD	TCGA	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	O75581	LRP6	P49841	GSK3B	S1544	Y1541S	1541	Missense	distal	-3	no	7.238	7.098	EPSD	TCGA;COSMIC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	O75581	LRP6	P49841	GSK3B	S1544	R1545Q	1545	Missense	proximal	1	no	7.238	6.290	EPSD	TCGA;COSMIC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	O75581	LRP6	P49841	GSK3B	T1572	S1579P	1579	Missense	distal	7	no	6.098	6.035	EPSD	TCGA;COSMIC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	O75581	LRP6	P49841	GSK3B	T1572	R1574Q	1574	Missense	proximal	2	no	6.098	6.303	EPSD	TCGA;COSMIC	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	O75581	LRP6	P49841	GSK3B	S1575	S1579P	1579	Missense	distal	4	no	7.459	4.487	EPSD	TCGA;COSMIC	6.007	Loss
CMGC_GSK_GSK3B_ST	O75581	LRP6	P49841	GSK3B	S1575	R1574Q	1574	Missense	proximal	-1	no	7.459	7.489	EPSD	TCGA;COSMIC	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	O75581	LRP6	P49841	GSK3B	S1586	S1579P	1579	Missense	distal	-7	no	7.141	7.139	EPSD	TCGA;COSMIC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	O75581	LRP6	P49841	GSK3B	S1590	S1596G	1596	Missense	distal	6	no	9.819	9.816	EPSD	TCGA;COSMIC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	O75581	LRP6	P49841	GSK3B	S1607	P1604T	1604	Missense	distal	-3	no	8.861	9.002	EPSD	TCGA;COSMIC	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	Q9H0B6	KLC2	P49841	GSK3B	S151	R144L	144	Missense	distal	-7	no	6.767	6.749	EPSD	TCGA;ICGC;COSMIC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	Q9H0B6	KLC2	P49841	GSK3B	S151	R144C	144	Missense	distal	-7	no	6.767	6.772	EPSD	TCGA;ICGC;COSMIC;GDSC;CCLE	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	Q9H0B6	KLC2	P49841	GSK3B	S151	S151P	151	Missense	central	0	yes	6.767	0.000	EPSD	TCGA;ICGC;COSMIC	6.007	Loss
CMGC_GSK_GSK3B_ST	Q9H0B6	KLC2	P49841	GSK3B	S151	A150V	150	Missense	proximal	-1	no	6.767	6.970	EPSD	TCGA;ICGC;COSMIC	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	Q9H0B6	KLC2	P49841	GSK3B	S175	E171G	171	Missense	distal	-4	no	10.231	10.400	EPSD	TCGA;ICGC;COSMIC	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	Q9H0B6	KLC2	P49841	GSK3B	S175	S179I	179	Missense	distal	4	no	10.231	6.909	EPSD	TCGA	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	Q9H0B6	KLC2	P49841	GSK3B	S175	A177T	177	Missense	proximal	2	no	10.231	10.349	EPSD	TCGA;ICGC;COSMIC	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	Q9H0B6	KLC2	P49841	GSK3B	S179	S179I	179	Missense	central	0	yes	7.675	0.000	EPSD	TCGA	6.007	Loss
CMGC_GSK_GSK3B_ST	Q9H0B6	KLC2	P49841	GSK3B	S179	A177T	177	Missense	proximal	-2	no	7.675	8.037	EPSD	TCGA;ICGC;COSMIC	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	Q9H0B6	KLC2	P49841	GSK3B	T450	R453H	453	Missense	distal	3	no	6.253	6.595	EPSD	TCGA;ICGC;COSMIC	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	Q9H0B6	KLC2	P49841	GSK3B	T450	L452P	452	Missense	proximal	2	no	6.253	6.637	EPSD	TCGA;COSMIC	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	Q9H0B6	KLC2	P49841	GSK3B	T450	T447A	447	Missense	distal	-3	no	6.253	6.249	EPSD	TCGA;ICGC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	Q9H0B6	KLC2	P49841	GSK3B	S539	D535A	535	Missense	distal	-4	no	7.780	7.221	EPSD	TCGA;ICGC;COSMIC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	Q9H0B6	KLC2	P49841	GSK3B	S539	R542C	542	Missense	distal	3	no	7.780	7.935	EPSD	TCGA;COSMIC	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	Q9H0B6	KLC2	P49841	GSK3B	S539	R542H	542	Missense	distal	3	no	7.780	8.122	EPSD	TCGA;ICGC;COSMIC;CCLE	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	Q9H0B6	KLC2	P49841	GSK3B	S602	R605H	605	Missense	distal	3	no	7.520	7.862	EPSD	TCGA;COSMIC	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	Q9H0B6	KLC2	P49841	GSK3B	S604	R605H	605	Missense	proximal	1	no	7.711	6.330	EPSD	TCGA;COSMIC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	Q9H0B6	KLC2	P49841	GSK3B	T606	R605H	605	Missense	proximal	-1	no	7.001	7.087	EPSD	TCGA;COSMIC	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	Q9H0B6	KLC2	P49841	GSK3B	S611	R605H	605	Missense	distal	-6	no	6.365	6.389	EPSD	TCGA;COSMIC	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	Q9H0B6	KLC2	P49841	GSK3B	S611	R617Q	617	Missense	distal	6	no	6.365	6.366	EPSD	TCGA;ICGC;COSMIC	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	Q9H0B6	KLC2	P49841	GSK3B	S615	R617Q	617	Missense	proximal	2	no	9.158	9.363	EPSD	TCGA;ICGC;COSMIC	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	Q6U7Q0	ZNF322	P49841	GSK3B	T79	S83I	83	Missense	distal	4	no	6.537	3.215	EPSD	TCGA;ICGC;COSMIC	6.007	Loss
CMGC_GSK_GSK3B_ST	Q6U7Q0	ZNF322	P49841	GSK3B	T79	T79I	79	Missense	central	0	yes	6.537	0.000	EPSD	TCGA;ICGC;COSMIC	6.007	Loss
CMGC_GSK_GSK3B_ST	Q6U7Q0	ZNF322	P49841	GSK3B	S391	A395P	395	Missense	distal	4	no	10.846	10.287	PhosphoSitePlus	TCGA;ICGC;COSMIC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	Q6U7Q0	ZNF322	P49841	GSK3B	S391	A395V	395	Missense	distal	4	no	10.846	10.868	PhosphoSitePlus	TCGA;ICGC	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	Q6U7Q0	ZNF322	P49841	GSK3B	S391	S384G	384	Missense	distal	-7	no	10.846	10.844	PhosphoSitePlus	TCGA;ICGC;COSMIC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	Q6R327	RICTOR	P49841	GSK3B	T31	D36N	36	Missense	distal	5	no	6.382	5.955	EPSD	TCGA;ICGC;COSMIC	6.007	Loss
CMGC_GSK_GSK3B_ST	Q6R327	RICTOR	P49841	GSK3B	T31	L30V	30	Missense	proximal	-1	no	6.382	6.505	EPSD	TCGA;ICGC;COSMIC	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	Q6R327	RICTOR	P49841	GSK3B	S221	I216L	216	Missense	distal	-5	no	7.476	7.113	EPSD	TCGA;ICGC;COSMIC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	Q6R327	RICTOR	P49841	GSK3B	S221	D217N	217	Missense	distal	-4	no	7.476	6.779	EPSD	TCGA;ICGC;COSMIC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	Q6R327	RICTOR	P49841	GSK3B	S265	T258S	258	Missense	distal	-7	no	7.362	7.335	EPSD	TCGA;ICGC;COSMIC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	Q6R327	RICTOR	P49841	GSK3B	S1031	E1038G	1038	Missense	distal	7	no	8.808	8.789	EPSD	TCGA;ICGC;COSMIC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	Q6R327	RICTOR	P49841	GSK3B	S1039	S1042L	1042	Missense	distal	3	no	7.585	7.284	EPSD	TCGA;ICGC;COSMIC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	Q6R327	RICTOR	P49841	GSK3B	S1039	E1038G	1038	Missense	proximal	-1	no	7.585	7.603	EPSD	TCGA;ICGC;COSMIC	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	Q6R327	RICTOR	P49841	GSK3B	S1122	G1117E	1117	Missense	distal	-5	no	6.052	6.017	EPSD	TCGA;ICGC;COSMIC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	Q6R327	RICTOR	P49841	GSK3B	S1122	L1120V	1120	Missense	proximal	-2	no	6.052	6.094	EPSD	TCGA;ICGC	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	Q6R327	RICTOR	P49841	GSK3B	T1152	Q1158H	1158	Missense	distal	6	no	7.207	7.201	EPSD	TCGA;ICGC;COSMIC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	Q6R327	RICTOR	P49841	GSK3B	T1175	H1168Y	1168	Missense	distal	-7	no	7.162	7.173	EPSD	TCGA;ICGC;COSMIC	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	Q6R327	RICTOR	P49841	GSK3B	T1175	T1172I	1172	Missense	distal	-3	no	7.162	7.251	EPSD	TCGA	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	Q6R327	RICTOR	P49841	GSK3B	S1227	T1222I	1222	Missense	distal	-5	no	9.055	9.238	EPSD	TCGA;ICGC;COSMIC	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	Q6R327	RICTOR	P49841	GSK3B	S1278	S1284L	1284	Missense	distal	6	no	6.547	6.542	EPSD	TCGA;ICGC;COSMIC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	Q6R327	RICTOR	P49841	GSK3B	S1284	S1284L	1284	Missense	central	0	yes	6.416	0.000	EPSD	TCGA;ICGC;COSMIC	6.007	Loss
CMGC_GSK_GSK3B_ST	Q6R327	RICTOR	P49841	GSK3B	S1320	S1323R	1323	Missense	distal	3	no	8.162	7.791	EPSD	TCGA;ICGC;COSMIC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	Q6R327	RICTOR	P49841	GSK3B	S1320	D1316N	1316	Missense	distal	-4	no	8.162	7.465	EPSD	TCGA;ICGC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	Q6R327	RICTOR	P49841	GSK3B	T1361	P1354S	1354	Missense	distal	-7	no	6.612	6.613	EPSD	TCGA;ICGC;COSMIC	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	Q6R327	RICTOR	P49841	GSK3B	T1361	T1363I	1363	Missense	proximal	2	no	6.612	6.546	EPSD	TCGA;ICGC;COSMIC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	Q6R327	RICTOR	P49841	GSK3B	T1376	K1382Q	1382	Missense	distal	6	no	6.930	6.932	EPSD	TCGA;ICGC	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	Q6R327	RICTOR	P49841	GSK3B	T1376	M1381V	1381	Missense	distal	5	no	6.930	6.567	EPSD	TCGA;ICGC;COSMIC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	Q6R327	RICTOR	P49841	GSK3B	T1376	S1378N	1378	Missense	proximal	2	no	6.930	6.398	EPSD	TCGA;ICGC;COSMIC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	Q6R327	RICTOR	P49841	GSK3B	S1411	S1407F	1407	Missense	distal	-4	no	7.061	5.907	EPSD	TCGA;ICGC;COSMIC	6.007	Loss
CMGC_GSK_GSK3B_ST	Q6R327	RICTOR	P49841	GSK3B	S1411	A1416V	1416	Missense	distal	5	no	7.061	6.635	EPSD	TCGA;ICGC;COSMIC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	Q6R327	RICTOR	P49841	GSK3B	S1411	R1405Q	1405	Missense	distal	-6	no	7.061	7.114	EPSD	TCGA;ICGC;COSMIC	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	Q6R327	RICTOR	P49841	GSK3B	S1581	S1585L	1585	Missense	distal	4	no	7.230	4.512	EPSD	TCGA;ICGC;COSMIC	6.007	Loss
CMGC_GSK_GSK3B_ST	Q6R327	RICTOR	P49841	GSK3B	S1581	S1588I	1588	Missense	distal	7	no	7.230	7.566	EPSD	TCGA;ICGC;COSMIC	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	Q6R327	RICTOR	P49841	GSK3B	S1585	S1585L	1585	Missense	central	0	yes	6.811	0.000	EPSD	TCGA;ICGC;COSMIC	6.007	Loss
CMGC_GSK_GSK3B_ST	Q6R327	RICTOR	P49841	GSK3B	S1585	S1588I	1588	Missense	distal	3	no	6.811	6.390	EPSD	TCGA;ICGC;COSMIC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	Q6R327	RICTOR	P49841	GSK3B	S1587	S1585L	1585	Missense	proximal	-2	no	6.424	6.350	EPSD	TCGA;ICGC;COSMIC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	Q6R327	RICTOR	P49841	GSK3B	S1587	S1588I	1588	Missense	proximal	1	no	6.424	6.387	EPSD	TCGA;ICGC;COSMIC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	Q6R327	RICTOR	P49841	GSK3B	S1588	S1585L	1585	Missense	distal	-3	no	7.334	7.344	EPSD	TCGA;ICGC;COSMIC	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	Q6R327	RICTOR	P49841	GSK3B	S1588	S1588I	1588	Missense	central	0	yes	7.334	0.000	EPSD	TCGA;ICGC;COSMIC	6.007	Loss
CMGC_GSK_GSK3B_ST	Q6R327	RICTOR	P49841	GSK3B	T1695	E1690K	1690	Missense	distal	-5	no	8.632	8.401	PhosphoSitePlus;EPSD	TCGA;COSMIC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	Q6R327	RICTOR	P49841	GSK3B	T1695	I1701T	1701	Missense	distal	6	no	8.632	8.634	PhosphoSitePlus;EPSD	TCGA;COSMIC	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	P01106	MYC	P49841	GSK3B	T58	E54D	54	Missense	distal	-4	no	12.188	12.185	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC;GDSC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	P01106	MYC	P49841	GSK3B	S161	S161L	161	Missense	central	0	yes	9.025	0.000	EPSD	TCGA;ICGC;COSMIC	6.007	Loss
CMGC_GSK_GSK3B_ST	P01106	MYC	P49841	GSK3B	S344	K341R	341	Missense	distal	-3	no	9.233	9.378	EPSD	TCGA;ICGC;COSMIC	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	P35612	ADD2	P49841	GSK3B	S11	T5A	5	Missense	distal	-6	no	7.707	7.776	EPSD	TCGA;ICGC;COSMIC;GDSC;CCLE	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	P35612	ADD2	P49841	GSK3B	S11	P15S	15	Missense	distal	4	no	7.707	10.679	EPSD	TCGA;ICGC;COSMIC	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	P35612	ADD2	P49841	GSK3B	S60	E65K	65	Missense	distal	5	no	6.927	6.060	EPSD	TCGA;ICGC;COSMIC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	P35612	ADD2	P49841	GSK3B	S60	M56I	56	Missense	distal	-4	no	6.927	5.504	EPSD	TCGA;ICGC;COSMIC	6.007	Loss
CMGC_GSK_GSK3B_ST	P35612	ADD2	P49841	GSK3B	S512	A513P	513	Missense	proximal	1	no	2.395	6.127	EPSD	TCGA;ICGC;COSMIC	6.007	Gain
CMGC_GSK_GSK3B_ST	P35612	ADD2	P49841	GSK3B	S528	V523I	523	Missense	distal	-5	no	7.100	6.992	EPSD	TCGA;ICGC;COSMIC;GDSC;CCLE	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	P35612	ADD2	P49841	GSK3B	S528	A521V	521	Missense	distal	-7	no	7.100	7.099	EPSD	TCGA;ICGC;COSMIC;GDSC;CCLE	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	P35612	ADD2	P49841	GSK3B	S528	S530N	530	Missense	proximal	2	no	7.100	6.568	EPSD	TCGA;ICGC;COSMIC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	P35612	ADD2	P49841	GSK3B	S528	I524V	524	Missense	distal	-4	no	7.100	8.349	EPSD	TCGA;ICGC;COSMIC	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	P35612	ADD2	P49841	GSK3B	S535	S530N	530	Missense	distal	-5	no	6.054	5.762	EPSD	TCGA;ICGC;COSMIC	6.007	Loss
CMGC_GSK_GSK3B_ST	P35612	ADD2	P49841	GSK3B	S592	A599V	599	Missense	distal	7	no	10.486	10.563	EPSD	TCGA;ICGC;COSMIC	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	P35612	ADD2	P49841	GSK3B	S592	S596Y	596	Missense	distal	4	no	10.486	6.973	EPSD	TCGA;ICGC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	P35612	ADD2	P49841	GSK3B	S592	S596P	596	Missense	distal	4	no	10.486	7.515	EPSD	TCGA;ICGC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	P35612	ADD2	P49841	GSK3B	S596	A599V	599	Missense	distal	3	no	7.516	7.645	EPSD	TCGA;ICGC;COSMIC	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	P35612	ADD2	P49841	GSK3B	S596	S596Y	596	Missense	central	0	yes	7.516	0.000	EPSD	TCGA;ICGC	6.007	Loss
CMGC_GSK_GSK3B_ST	P35612	ADD2	P49841	GSK3B	S596	S600F	600	Missense	distal	4	no	7.516	3.902	EPSD	TCGA;ICGC;COSMIC	6.007	Loss
CMGC_GSK_GSK3B_ST	P35612	ADD2	P49841	GSK3B	S596	S596P	596	Missense	central	0	yes	7.516	0.000	EPSD	TCGA;ICGC	6.007	Loss
CMGC_GSK_GSK3B_ST	P35612	ADD2	P49841	GSK3B	S600	A599V	599	Missense	proximal	-1	no	12.031	12.234	EPSD	TCGA;ICGC;COSMIC	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	P35612	ADD2	P49841	GSK3B	S600	S596Y	596	Missense	distal	-4	no	12.031	11.231	EPSD	TCGA;ICGC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	P35612	ADD2	P49841	GSK3B	S600	S600F	600	Missense	central	0	yes	12.031	0.000	EPSD	TCGA;ICGC;COSMIC	6.007	Loss
CMGC_GSK_GSK3B_ST	P35612	ADD2	P49841	GSK3B	S600	S596P	596	Missense	distal	-4	no	12.031	11.468	EPSD	TCGA;ICGC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	P35612	ADD2	P49841	GSK3B	S604	A599V	599	Missense	distal	-5	no	7.723	8.025	EPSD	TCGA;ICGC;COSMIC	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	P35612	ADD2	P49841	GSK3B	S604	S600F	600	Missense	distal	-4	no	7.723	6.569	EPSD	TCGA;ICGC;COSMIC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	P35612	ADD2	P49841	GSK3B	S613	E610K	610	Missense	distal	-3	no	10.662	10.672	PhosphoSitePlus;EPSD	TCGA;COSMIC	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	P35612	ADD2	P49841	GSK3B	S617	S621F	621	Missense	distal	4	no	9.420	5.806	EPSD	TCGA;ICGC;COSMIC	6.007	Loss
CMGC_GSK_GSK3B_ST	P35612	ADD2	P49841	GSK3B	S617	E610K	610	Missense	distal	-7	no	9.420	9.409	EPSD	TCGA;COSMIC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	P35612	ADD2	P49841	GSK3B	S667	E660K	660	Missense	distal	-7	no	6.656	6.645	EPSD	TCGA;ICGC;COSMIC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	P35612	ADD2	P49841	GSK3B	T671	T675M	675	Missense	distal	4	no	6.090	4.724	EPSD	TCGA;COSMIC	6.007	Loss
CMGC_GSK_GSK3B_ST	P35612	ADD2	P49841	GSK3B	S686	G690S	690	Missense	distal	4	no	4.581	7.824	EPSD	TCGA;ICGC;COSMIC	6.007	Gain
CMGC_GSK_GSK3B_ST	P35612	ADD2	P49841	GSK3B	S689	S686L	686	Missense	distal	-3	no	8.096	8.105	EPSD	TCGA;ICGC;COSMIC	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	P35612	ADD2	P49841	GSK3B	S689	D682H	682	Missense	distal	-7	no	8.096	8.111	EPSD	TCGA;ICGC;COSMIC	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	P35612	ADD2	P49841	GSK3B	S689	G690S	690	Missense	proximal	1	no	8.096	7.445	EPSD	TCGA;ICGC;COSMIC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	P35612	ADD2	P49841	GSK3B	S693	G690S	690	Missense	distal	-3	no	12.171	12.175	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	P35612	ADD2	P49841	GSK3B	S697	G690S	690	Missense	distal	-7	no	10.178	10.180	EPSD	TCGA;ICGC;COSMIC	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	Q15691	MAPRE1	P49841	GSK3B	T135	P139S	139	Missense	distal	4	no	3.760	6.731	EPSD	TCGA;ICGC;COSMIC	6.007	Gain
CMGC_GSK_GSK3B_ST	Q15691	MAPRE1	P49841	GSK3B	S165	P160S	160	Missense	distal	-5	no	6.685	6.841	EPSD	TCGA;ICGC;COSMIC	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	Q15691	MAPRE1	P49841	GSK3B	S165	A171V	171	Missense	distal	6	no	6.685	6.676	EPSD	TCGA;ICGC;COSMIC;GDSC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	Q15691	MAPRE1	P49841	GSK3B	S165	R168K	168	Missense	distal	3	no	6.685	6.929	EPSD	TCGA;ICGC	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	P25054	APC	P49841	GSK3B	S107	G108A	108	Missense	proximal	1	no	7.230	6.692	EPSD	TCGA;ICGC;COSMIC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	P25054	APC	P49841	GSK3B	S107	E109A	109	Missense	proximal	2	no	7.230	7.325	EPSD	TCGA;ICGC;COSMIC	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	P25054	APC	P49841	GSK3B	S111	G108A	108	Missense	distal	-3	no	8.187	8.211	EPSD	TCGA;ICGC;COSMIC	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	P25054	APC	P49841	GSK3B	S111	E109A	109	Missense	proximal	-2	no	8.187	7.955	EPSD	TCGA;ICGC;COSMIC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	P25054	APC	P49841	GSK3B	S127	N125S	125	Missense	proximal	-2	no	6.184	6.412	EPSD	TCGA	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	P25054	APC	P49841	GSK3B	S744	P745H	745	Missense	proximal	1	no	10.614	6.914	EPSD	TCGA;ICGC;COSMIC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	P25054	APC	P49841	GSK3B	S744	N741S	741	Missense	distal	-3	no	10.614	10.709	EPSD	TCGA;ICGC;COSMIC	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	P25054	APC	P49841	GSK3B	S747	P745H	745	Missense	proximal	-2	no	6.209	5.848	EPSD	TCGA;ICGC;COSMIC	6.007	Loss
CMGC_GSK_GSK3B_ST	P25054	APC	P49841	GSK3B	S747	N741S	741	Missense	distal	-6	no	6.209	6.212	EPSD	TCGA;ICGC;COSMIC	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	P25054	APC	P49841	GSK3B	S780	D777G	777	Missense	distal	-3	no	7.539	7.489	EPSD	TCGA;ICGC;COSMIC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	P25054	APC	P49841	GSK3B	S780	R786H	786	Missense	distal	6	no	7.539	7.534	EPSD	TCGA;ICGC;COSMIC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	P25054	APC	P49841	GSK3B	S780	N778S	778	Missense	proximal	-2	no	7.539	7.768	EPSD	TCGA;ICGC;COSMIC	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	P25054	APC	P49841	GSK3B	T899	S905R	905	Missense	distal	6	no	6.638	6.633	EPSD	TCGA	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	P25054	APC	P49841	GSK3B	T899	S906Y	906	Missense	distal	7	no	6.638	7.080	EPSD	TCGA;ICGC;COSMIC	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	P25054	APC	P49841	GSK3B	S906	S905R	905	Missense	proximal	-1	no	6.850	6.713	EPSD	TCGA	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	P25054	APC	P49841	GSK3B	S906	S906Y	906	Missense	central	0	yes	6.850	0.000	EPSD	TCGA;ICGC;COSMIC	6.007	Loss
CMGC_GSK_GSK3B_ST	P25054	APC	P49841	GSK3B	S966	S959Y	959	Missense	distal	-7	no	8.445	8.474	EPSD	TCGA;ICGC;COSMIC	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	P25054	APC	P49841	GSK3B	S966	S966G	966	Missense	central	0	yes	8.445	0.000	EPSD	TCGA;ICGC;COSMIC	6.007	Loss
CMGC_GSK_GSK3B_ST	P25054	APC	P49841	GSK3B	S1028	L1029I	1029	Missense	proximal	1	no	7.279	6.258	EPSD	TCGA;ICGC;COSMIC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	P25054	APC	P49841	GSK3B	S1028	Y1027H	1027	Missense	proximal	-1	no	7.279	7.368	EPSD	TCGA;ICGC;COSMIC	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	P25054	APC	P49841	GSK3B	S1038	L1036W	1036	Missense	proximal	-2	no	7.492	7.656	EPSD	TCGA;ICGC;COSMIC	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	P25054	APC	P49841	GSK3B	S1038	L1036F	1036	Missense	proximal	-2	no	7.492	7.235	EPSD	TCGA;ICGC;COSMIC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	P25054	APC	P49841	GSK3B	S1100	V1099L	1099	Missense	proximal	-1	no	9.022	8.899	EPSD	TCGA;ICGC;COSMIC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	P25054	APC	P49841	GSK3B	S1100	R1105Q	1105	Missense	distal	5	no	9.022	8.683	EPSD	TCGA;ICGC;COSMIC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	P25054	APC	P49841	GSK3B	S1214	M1211V	1211	Missense	distal	-3	no	5.884	6.080	EPSD	TCGA;ICGC;COSMIC	6.007	Gain
CMGC_GSK_GSK3B_ST	P25054	APC	P49841	GSK3B	T1218	T1218M	1218	Missense	central	0	yes	6.412	0.000	EPSD	TCGA;ICGC;COSMIC	6.007	Loss
CMGC_GSK_GSK3B_ST	P25054	APC	P49841	GSK3B	T1218	S1215I	1215	Missense	distal	-3	no	6.412	6.525	EPSD	TCGA;ICGC;COSMIC	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	P25054	APC	P49841	GSK3B	T1218	S1219F	1219	Missense	proximal	1	no	6.412	6.026	EPSD	TCGA;ICGC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	P25054	APC	P49841	GSK3B	S1219	T1218M	1218	Missense	proximal	-1	no	6.651	6.675	EPSD	TCGA;ICGC;COSMIC	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	P25054	APC	P49841	GSK3B	S1219	S1215I	1215	Missense	distal	-4	no	6.651	4.168	EPSD	TCGA;ICGC;COSMIC	6.007	Loss
CMGC_GSK_GSK3B_ST	P25054	APC	P49841	GSK3B	S1219	S1219F	1219	Missense	central	0	yes	6.651	0.000	EPSD	TCGA;ICGC	6.007	Loss
CMGC_GSK_GSK3B_ST	P25054	APC	P49841	GSK3B	T1220	S1215I	1215	Missense	distal	-5	no	5.616	6.088	EPSD	TCGA;ICGC;COSMIC	6.007	Gain
CMGC_GSK_GSK3B_ST	P25054	APC	P49841	GSK3B	T1267	F1271I	1271	Missense	distal	4	no	5.846	6.139	EPSD	TCGA;ICGC;COSMIC	6.007	Gain
CMGC_GSK_GSK3B_ST	P25054	APC	P49841	GSK3B	S1272	P1268A	1268	Missense	distal	-4	no	6.638	6.041	EPSD	TCGA;ICGC;COSMIC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	P25054	APC	P49841	GSK3B	S1272	S1278L	1278	Missense	distal	6	no	6.638	6.633	EPSD	TCGA;ICGC;COSMIC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	P25054	APC	P49841	GSK3B	S1272	F1271I	1271	Missense	proximal	-1	no	6.638	6.619	EPSD	TCGA;ICGC;COSMIC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	P25054	APC	P49841	GSK3B	S1272	E1265Q	1265	Missense	distal	-7	no	6.638	6.620	EPSD	TCGA;ICGC;COSMIC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	P25054	APC	P49841	GSK3B	S1272	I1269L	1269	Missense	distal	-3	no	6.638	6.534	EPSD	TCGA;ICGC;COSMIC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	P25054	APC	P49841	GSK3B	S1272	S1272L	1272	Missense	central	0	yes	6.638	0.000	EPSD	TCGA;ICGC;COSMIC	6.007	Loss
CMGC_GSK_GSK3B_ST	P25054	APC	P49841	GSK3B	S1272	L1277V	1277	Missense	distal	5	no	6.638	6.463	EPSD	TCGA	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	P25054	APC	P49841	GSK3B	S1278	S1278L	1278	Missense	central	0	yes	6.066	0.000	EPSD	TCGA;ICGC;COSMIC	6.007	Loss
CMGC_GSK_GSK3B_ST	P25054	APC	P49841	GSK3B	S1278	F1271I	1271	Missense	distal	-7	no	6.066	6.084	EPSD	TCGA;ICGC;COSMIC	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	P25054	APC	P49841	GSK3B	S1278	S1272L	1272	Missense	distal	-6	no	6.066	6.065	EPSD	TCGA;ICGC;COSMIC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	P25054	APC	P49841	GSK3B	S1278	L1277V	1277	Missense	proximal	-1	no	6.066	6.190	EPSD	TCGA	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	P25054	APC	P49841	GSK3B	S1360	S1360C	1360	Missense	central	0	yes	10.460	0.000	EPSD	TCGA;ICGC;COSMIC	6.007	Loss
CMGC_GSK_GSK3B_ST	P25054	APC	P49841	GSK3B	S1360	Q1367E	1367	Missense	distal	7	no	10.460	10.409	EPSD	TCGA;ICGC;COSMIC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	P25054	APC	P49841	GSK3B	S1360	A1358V	1358	Missense	proximal	-2	no	10.460	10.762	EPSD	TCGA;ICGC;COSMIC	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	P25054	APC	P49841	GSK3B	S1360	P1361S	1361	Missense	proximal	1	no	10.460	6.615	EPSD	TCGA;ICGC;COSMIC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	P25054	APC	P49841	GSK3B	S1364	S1360C	1360	Missense	distal	-4	no	7.800	5.686	EPSD	TCGA;ICGC;COSMIC	6.007	Loss
CMGC_GSK_GSK3B_ST	P25054	APC	P49841	GSK3B	S1364	Q1367E	1367	Missense	distal	3	no	7.800	7.819	EPSD	TCGA;ICGC;COSMIC	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	P25054	APC	P49841	GSK3B	S1364	A1358V	1358	Missense	distal	-6	no	7.800	7.722	EPSD	TCGA;ICGC;COSMIC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	P25054	APC	P49841	GSK3B	S1364	P1361S	1361	Missense	distal	-3	no	7.800	7.917	EPSD	TCGA;ICGC;COSMIC	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	P25054	APC	P49841	GSK3B	T1368	Q1367E	1367	Missense	proximal	-1	no	7.906	8.001	EPSD	TCGA;ICGC;COSMIC	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	P25054	APC	P49841	GSK3B	T1368	P1361S	1361	Missense	distal	-7	no	7.906	7.907	EPSD	TCGA;ICGC;COSMIC	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	P25054	APC	P49841	GSK3B	S1371	Q1367E	1367	Missense	distal	-4	no	6.484	6.716	EPSD	TCGA;ICGC;COSMIC	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	P25054	APC	P49841	GSK3B	T1380	R1386K	1386	Missense	distal	6	no	6.505	6.504	EPSD	TCGA;ICGC;COSMIC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	P25054	APC	P49841	GSK3B	T1380	T1380P	1380	Missense	central	0	yes	6.505	0.000	EPSD	TCGA;ICGC;COSMIC	6.007	Loss
CMGC_GSK_GSK3B_ST	P25054	APC	P49841	GSK3B	T1380	P1381S	1381	Missense	proximal	1	no	6.505	2.660	EPSD	TCGA;ICGC;COSMIC	6.007	Loss
CMGC_GSK_GSK3B_ST	P25054	APC	P49841	GSK3B	S1385	R1386K	1386	Missense	proximal	1	no	6.310	5.084	EPSD	TCGA;ICGC;COSMIC	6.007	Loss
CMGC_GSK_GSK3B_ST	P25054	APC	P49841	GSK3B	S1385	S1389F	1389	Missense	distal	4	no	6.310	2.696	EPSD	TCGA;ICGC;COSMIC	6.007	Loss
CMGC_GSK_GSK3B_ST	P25054	APC	P49841	GSK3B	S1385	T1380P	1380	Missense	distal	-5	no	6.310	5.865	EPSD	TCGA;ICGC;COSMIC	6.007	Loss
CMGC_GSK_GSK3B_ST	P25054	APC	P49841	GSK3B	S1385	P1381S	1381	Missense	distal	-4	no	6.310	6.874	EPSD	TCGA;ICGC;COSMIC	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	P25054	APC	P49841	GSK3B	S1398	L1393I	1393	Missense	distal	-5	no	5.949	6.312	EPSD	TCGA;ICGC;COSMIC	6.007	Gain
CMGC_GSK_GSK3B_ST	P25054	APC	P49841	GSK3B	S1398	S1400L	1400	Missense	proximal	2	no	5.949	6.009	EPSD	TCGA;ICGC;COSMIC;CCLE	6.007	Gain
CMGC_GSK_GSK3B_ST	P25054	APC	P49841	GSK3B	S1426	D1422N	1422	Missense	distal	-4	no	7.675	6.978	EPSD	TCGA;ICGC;COSMIC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	P25054	APC	P49841	GSK3B	S1426	S1421N	1421	Missense	distal	-5	no	7.675	7.383	EPSD	TCGA;ICGC;COSMIC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	P25054	APC	P49841	GSK3B	T1438	R1435T	1435	Missense	distal	-3	no	8.114	7.970	EPSD	TCGA	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	P25054	APC	P49841	GSK3B	T1438	S1434G	1434	Missense	distal	-4	no	8.114	7.686	EPSD	TCGA;ICGC;COSMIC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	P25054	APC	P49841	GSK3B	T1438	P1442H	1442	Missense	distal	4	no	8.114	7.329	EPSD	TCGA;ICGC;COSMIC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	P25054	APC	P49841	GSK3B	T1438	S1434I	1434	Missense	distal	-4	no	8.114	5.631	EPSD	TCGA;ICGC;COSMIC	6.007	Loss
CMGC_GSK_GSK3B_ST	P25054	APC	P49841	GSK3B	S1501	E1494Q	1494	Missense	distal	-7	no	8.486	8.469	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	P25054	APC	P49841	GSK3B	S1501	A1508D	1508	Missense	distal	7	no	8.486	8.193	EPSD;PhosphoSitePlus	TCGA;ICGC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	P25054	APC	P49841	GSK3B	S1503	A1508D	1508	Missense	distal	5	no	6.247	6.428	PhosphoSitePlus;EPSD	TCGA;ICGC	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	P25054	APC	P49841	GSK3B	T1633	R1640W	1640	Missense	distal	7	no	6.346	6.455	EPSD	TCGA;ICGC;COSMIC	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	P25054	APC	P49841	GSK3B	T1633	P1634L	1634	Missense	proximal	1	no	6.346	3.486	EPSD	TCGA;ICGC;COSMIC	6.007	Loss
CMGC_GSK_GSK3B_ST	P25054	APC	P49841	GSK3B	S1652	D1659V	1659	Missense	distal	7	no	6.674	7.044	EPSD	TCGA;ICGC;COSMIC	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	P25054	APC	P49841	GSK3B	S1664	D1659V	1659	Missense	distal	-5	no	8.205	8.512	EPSD	TCGA;ICGC;COSMIC	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	P25054	APC	P49841	GSK3B	S1754	Q1749K	1749	Missense	distal	-5	no	6.118	6.175	EPSD	TCGA;ICGC;COSMIC	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	P25054	APC	P49841	GSK3B	S1754	S1758F	1758	Missense	distal	4	no	6.118	2.503	EPSD	TCGA;ICGC;COSMIC	6.007	Loss
CMGC_GSK_GSK3B_ST	P25054	APC	P49841	GSK3B	S1754	S1757Y	1757	Missense	distal	3	no	6.118	5.695	EPSD	TCGA;ICGC	6.007	Loss
CMGC_GSK_GSK3B_ST	P25054	APC	P49841	GSK3B	S1754	A1755V	1755	Missense	proximal	1	no	6.118	6.859	EPSD	TCGA;ICGC;COSMIC	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	P25054	APC	P49841	GSK3B	T1847	T1847M	1847	Missense	central	0	yes	6.378	0.000	EPSD	TCGA	6.007	Loss
CMGC_GSK_GSK3B_ST	P25054	APC	P49841	GSK3B	T1847	Y1846C	1846	Missense	proximal	-1	no	6.378	6.482	EPSD	TCGA;ICGC;COSMIC	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	P25054	APC	P49841	GSK3B	T1852	T1847M	1847	Missense	distal	-5	no	6.569	6.581	EPSD	TCGA	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	P25054	APC	P49841	GSK3B	T1852	Y1846C	1846	Missense	distal	-6	no	6.569	6.643	EPSD	TCGA;ICGC;COSMIC	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	P25054	APC	P49841	GSK3B	S1857	S1861Y	1861	Missense	distal	4	no	8.480	4.967	EPSD	TCGA;ICGC;COSMIC	6.007	Loss
CMGC_GSK_GSK3B_ST	P25054	APC	P49841	GSK3B	T2017	F2021L	2021	Missense	distal	4	no	5.960	6.856	EPSD	TCGA;ICGC;COSMIC	6.007	Gain
CMGC_GSK_GSK3B_ST	P25054	APC	P49841	GSK3B	S2022	T2017A	2017	Missense	distal	-5	no	6.546	6.534	EPSD	TCGA;ICGC;COSMIC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	P25054	APC	P49841	GSK3B	S2022	S2026Y	2026	Missense	distal	4	no	6.546	3.033	EPSD	TCGA;ICGC;COSMIC	6.007	Loss
CMGC_GSK_GSK3B_ST	P25054	APC	P49841	GSK3B	S2022	T2017I	2017	Missense	distal	-5	no	6.546	6.729	EPSD	TCGA;ICGC	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	P25054	APC	P49841	GSK3B	S2022	F2021L	2021	Missense	proximal	-1	no	6.546	6.601	EPSD	TCGA;ICGC;COSMIC	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	P25054	APC	P49841	GSK3B	S2022	S2029Y	2029	Missense	distal	7	no	6.546	6.988	EPSD	TCGA;ICGC;COSMIC	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	P25054	APC	P49841	GSK3B	S2022	S2029F	2029	Missense	distal	7	no	6.546	6.623	EPSD	TCGA;ICGC;COSMIC	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	P25054	APC	P49841	GSK3B	S2174	K2180R	2180	Missense	distal	6	no	6.229	6.230	EPSD	TCGA;ICGC;COSMIC	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	P25054	APC	P49841	GSK3B	S2174	L2168I	2168	Missense	distal	-6	no	6.229	6.167	EPSD	TCGA;ICGC;COSMIC;CCLE	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	P25054	APC	P49841	GSK3B	S2240	T2243A	2243	Missense	distal	3	no	6.762	6.458	EPSD	TCGA;ICGC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	P25054	APC	P49841	GSK3B	S2240	S2242N	2242	Missense	proximal	2	no	6.762	6.230	EPSD	TCGA;ICGC;COSMIC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	P25054	APC	P49841	GSK3B	S2240	P2234S	2234	Missense	distal	-6	no	6.762	6.742	EPSD	TCGA;ICGC;COSMIC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	P25054	APC	P49841	GSK3B	S2240	S2242I	2242	Missense	proximal	2	no	6.762	6.823	EPSD	TCGA;ICGC	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	P25054	APC	P49841	GSK3B	S2240	P2245H	2245	Missense	distal	5	no	6.762	5.136	EPSD	TCGA;ICGC	6.007	Loss
CMGC_GSK_GSK3B_ST	P25054	APC	P49841	GSK3B	T2243	T2243A	2243	Missense	central	0	yes	6.497	0.000	EPSD	TCGA;ICGC	6.007	Loss
CMGC_GSK_GSK3B_ST	P25054	APC	P49841	GSK3B	T2243	G2250V	2250	Missense	distal	7	no	6.497	6.903	EPSD	TCGA;ICGC;COSMIC	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	P25054	APC	P49841	GSK3B	T2243	S2242N	2242	Missense	proximal	-1	no	6.497	6.559	EPSD	TCGA;ICGC;COSMIC	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	P25054	APC	P49841	GSK3B	T2243	S2242I	2242	Missense	proximal	-1	no	6.497	6.348	EPSD	TCGA;ICGC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	P25054	APC	P49841	GSK3B	T2243	P2245H	2245	Missense	proximal	2	no	6.497	5.728	EPSD	TCGA;ICGC	6.007	Loss
CMGC_GSK_GSK3B_ST	P25054	APC	P49841	GSK3B	T2255	G2250V	2250	Missense	distal	-5	no	6.155	6.268	EPSD	TCGA;ICGC;COSMIC	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	P25054	APC	P49841	GSK3B	T2255	P2256L	2256	Missense	proximal	1	no	6.155	3.294	EPSD	TCGA;ICGC;COSMIC	6.007	Loss
CMGC_GSK_GSK3B_ST	P25054	APC	P49841	GSK3B	T2255	L2253F	2253	Missense	proximal	-2	no	6.155	5.898	EPSD	TCGA;ICGC;COSMIC	6.007	Loss
CMGC_GSK_GSK3B_ST	P25054	APC	P49841	GSK3B	T2255	L2253I	2253	Missense	proximal	-2	no	6.155	6.218	EPSD	TCGA;ICGC;COSMIC	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	P25054	APC	P49841	GSK3B	S2258	P2256L	2256	Missense	proximal	-2	no	7.079	6.749	EPSD	TCGA;ICGC;COSMIC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	P25054	APC	P49841	GSK3B	S2258	L2253F	2253	Missense	distal	-5	no	7.079	7.530	EPSD	TCGA;ICGC;COSMIC	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	P25054	APC	P49841	GSK3B	S2258	L2253I	2253	Missense	distal	-5	no	7.079	7.443	EPSD	TCGA;ICGC;COSMIC	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	P25054	APC	P49841	GSK3B	S2260	P2256L	2256	Missense	distal	-4	no	6.088	5.301	EPSD	TCGA;ICGC;COSMIC	6.007	Loss
CMGC_GSK_GSK3B_ST	P25054	APC	P49841	GSK3B	S2260	L2253F	2253	Missense	distal	-7	no	6.088	6.098	EPSD	TCGA;ICGC;COSMIC	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	P25054	APC	P49841	GSK3B	S2260	L2253I	2253	Missense	distal	-7	no	6.088	6.115	EPSD	TCGA;ICGC;COSMIC	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	P25054	APC	P49841	GSK3B	S2270	S2277A	2277	Missense	distal	7	no	6.995	7.343	EPSD	TCGA;ICGC;COSMIC	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	P25054	APC	P49841	GSK3B	S2283	S2277A	2277	Missense	distal	-6	no	6.401	6.412	EPSD	TCGA;ICGC;COSMIC	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	P25054	APC	P49841	GSK3B	S2300	S2307L	2307	Missense	distal	7	no	9.383	9.369	EPSD	TCGA;ICGC;COSMIC;CCLE	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	P25054	APC	P49841	GSK3B	S2300	S2300C	2300	Missense	central	0	yes	9.383	0.000	EPSD	TCGA;ICGC;COSMIC	6.007	Loss
CMGC_GSK_GSK3B_ST	P25054	APC	P49841	GSK3B	S2300	G2293V	2293	Missense	distal	-7	no	9.383	9.406	EPSD	TCGA;ICGC;COSMIC	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	P25054	APC	P49841	GSK3B	S2300	S2300Y	2300	Missense	central	0	yes	9.383	0.000	EPSD	TCGA	6.007	Loss
CMGC_GSK_GSK3B_ST	P25054	APC	P49841	GSK3B	S2304	S2307L	2307	Missense	distal	3	no	10.068	9.768	EPSD	TCGA;ICGC;COSMIC;CCLE	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	P25054	APC	P49841	GSK3B	S2304	S2300C	2300	Missense	distal	-4	no	10.068	7.954	EPSD	TCGA;ICGC;COSMIC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	P25054	APC	P49841	GSK3B	S2304	S2300Y	2300	Missense	distal	-4	no	10.068	9.268	EPSD	TCGA	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	P25054	APC	P49841	GSK3B	S2307	S2307L	2307	Missense	central	0	yes	7.358	0.000	EPSD	TCGA;ICGC;COSMIC;CCLE	6.007	Loss
CMGC_GSK_GSK3B_ST	P25054	APC	P49841	GSK3B	S2307	S2300C	2300	Missense	distal	-7	no	7.358	7.380	EPSD	TCGA;ICGC;COSMIC	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	P25054	APC	P49841	GSK3B	S2307	A2313S	2313	Missense	distal	6	no	7.358	7.359	EPSD	TCGA;ICGC;COSMIC	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	P25054	APC	P49841	GSK3B	S2307	S2300Y	2300	Missense	distal	-7	no	7.358	7.386	EPSD	TCGA	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	P25054	APC	P49841	GSK3B	T2308	S2307L	2307	Missense	proximal	-1	no	6.717	6.642	EPSD	TCGA;ICGC;COSMIC;CCLE	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	P25054	APC	P49841	GSK3B	T2308	A2313S	2313	Missense	distal	5	no	6.717	6.792	EPSD	TCGA;ICGC;COSMIC	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	P25054	APC	P49841	GSK3B	T2348	P2346S	2346	Missense	proximal	-2	no	6.595	6.339	EPSD	TCGA;ICGC;COSMIC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	P25054	APC	P49841	GSK3B	S2350	P2346S	2346	Missense	distal	-4	no	7.290	7.853	EPSD	TCGA;ICGC;COSMIC	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	P25054	APC	P49841	GSK3B	S2390	A2388V	2388	Missense	proximal	-2	no	7.039	7.341	EPSD	TCGA;ICGC;COSMIC;CCLE	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	P25054	APC	P49841	GSK3B	S2425	S2429F	2429	Missense	distal	4	no	7.244	3.630	EPSD	TCGA;COSMIC	6.007	Loss
CMGC_GSK_GSK3B_ST	P25054	APC	P49841	GSK3B	S2425	D2430H	2430	Missense	distal	5	no	7.244	6.465	EPSD	TCGA;ICGC;COSMIC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	P25054	APC	P49841	GSK3B	S2429	S2429F	2429	Missense	central	0	yes	6.304	0.000	EPSD	TCGA;COSMIC	6.007	Loss
CMGC_GSK_GSK3B_ST	P25054	APC	P49841	GSK3B	S2429	D2430H	2430	Missense	proximal	1	no	6.304	5.707	EPSD	TCGA;ICGC;COSMIC	6.007	Loss
CMGC_GSK_GSK3B_ST	P25054	APC	P49841	GSK3B	S2449	F2443L	2443	Missense	distal	-6	no	6.896	6.948	EPSD	TCGA;ICGC;COSMIC	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	P25054	APC	P49841	GSK3B	S2449	F2443Y	2443	Missense	distal	-6	no	6.896	6.863	EPSD	TCGA;ICGC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	P25054	APC	P49841	GSK3B	S2464	S2464Y	2464	Missense	central	0	yes	6.799	0.000	EPSD	TCGA;ICGC;COSMIC	6.007	Loss
CMGC_GSK_GSK3B_ST	P25054	APC	P49841	GSK3B	S2466	A2472D	2472	Missense	distal	6	no	7.295	7.289	EPSD	TCGA;ICGC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	P25054	APC	P49841	GSK3B	S2466	S2464Y	2464	Missense	proximal	-2	no	7.295	6.976	EPSD	TCGA;ICGC;COSMIC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	P25054	APC	P49841	GSK3B	S2469	A2472D	2472	Missense	distal	3	no	7.641	8.073	EPSD	TCGA;ICGC	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	P25054	APC	P49841	GSK3B	S2469	S2464Y	2464	Missense	distal	-5	no	7.641	8.294	EPSD	TCGA;ICGC;COSMIC	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	P25054	APC	P49841	GSK3B	S2473	A2472D	2472	Missense	proximal	-1	no	10.333	10.427	EPSD	TCGA;ICGC	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	P25054	APC	P49841	GSK3B	S2512	P2509S	2509	Missense	distal	-3	no	6.003	6.120	EPSD	TCGA;ICGC;COSMIC	6.007	Gain
CMGC_GSK_GSK3B_ST	P25054	APC	P49841	GSK3B	S2512	I2515V	2515	Missense	distal	3	no	6.003	6.216	EPSD	TCGA;ICGC;COSMIC	6.007	Gain
CMGC_GSK_GSK3B_ST	P25054	APC	P49841	GSK3B	S2531	R2525C	2525	Missense	distal	-6	no	6.477	6.523	EPSD	TCGA;ICGC;COSMIC	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	P25054	APC	P49841	GSK3B	S2531	H2532Y	2532	Missense	proximal	1	no	6.477	6.859	EPSD	TCGA;ICGC;COSMIC	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	P25054	APC	P49841	GSK3B	S2535	I2541V	2541	Missense	distal	6	no	10.565	10.555	EPSD	TCGA;ICGC;COSMIC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	P25054	APC	P49841	GSK3B	S2535	P2540S	2540	Missense	distal	5	no	10.565	9.611	EPSD	TCGA;ICGC;COSMIC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	P25054	APC	P49841	GSK3B	S2535	H2532Y	2532	Missense	distal	-3	no	10.565	10.593	EPSD	TCGA;ICGC;COSMIC	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	P25054	APC	P49841	GSK3B	T2563	S2569N	2569	Missense	distal	6	no	7.337	7.331	EPSD	TCGA;ICGC;COSMIC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	P25054	APC	P49841	GSK3B	T2567	L2574I	2574	Missense	distal	7	no	5.736	6.086	EPSD	TCGA;ICGC;COSMIC	6.007	Gain
CMGC_GSK_GSK3B_ST	P25054	APC	P49841	GSK3B	S2621	N2624D	2624	Missense	distal	3	no	9.358	9.405	EPSD	TCGA;ICGC;COSMIC	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	P25054	APC	P49841	GSK3B	S2625	N2624D	2624	Missense	proximal	-1	no	6.567	6.445	EPSD	TCGA;ICGC;COSMIC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	P25054	APC	P49841	GSK3B	S2627	N2624D	2624	Missense	distal	-3	no	7.373	7.514	EPSD	TCGA;ICGC;COSMIC	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	P25054	APC	P49841	GSK3B	T2679	S2674Y	2674	Missense	distal	-5	no	6.363	7.016	EPSD	TCGA;ICGC;COSMIC	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	P25054	APC	P49841	GSK3B	T2760	S2755Y	2755	Missense	distal	-5	no	5.679	6.331	EPSD	TCGA;ICGC;COSMIC	6.007	Gain
CMGC_GSK_GSK3B_ST	P25054	APC	P49841	GSK3B	S2763	R2759H	2759	Missense	distal	-4	no	6.296	6.395	EPSD	TCGA;ICGC;COSMIC	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	P25054	APC	P49841	GSK3B	S2768	G2775V	2775	Missense	distal	7	no	7.195	7.601	EPSD	TCGA;ICGC;COSMIC	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	P25054	APC	P49841	GSK3B	S2772	G2775V	2775	Missense	distal	3	no	9.633	9.382	EPSD	TCGA;ICGC;COSMIC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	P25054	APC	P49841	GSK3B	S2772	A2779V	2779	Missense	distal	7	no	9.633	9.711	EPSD	TCGA;ICGC;COSMIC	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	P25054	APC	P49841	GSK3B	S2789	F2784C	2784	Missense	distal	-5	no	8.105	8.065	EPSD	TCGA;ICGC;COSMIC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	P25054	APC	P49841	GSK3B	S2789	S2794T	2794	Missense	distal	5	no	8.105	8.083	EPSD	TCGA;ICGC;COSMIC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	P25054	APC	P49841	GSK3B	S2789	P2783L	2783	Missense	distal	-6	no	8.105	8.083	EPSD	TCGA;ICGC;COSMIC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	P25054	APC	P49841	GSK3B	S2793	S2794T	2794	Missense	proximal	1	no	5.697	6.351	EPSD	TCGA;ICGC;COSMIC	6.007	Gain
CMGC_GSK_GSK3B_ST	P25054	APC	P49841	GSK3B	S2799	R2801W	2801	Missense	proximal	2	no	6.612	6.182	EPSD	TCGA;ICGC;COSMIC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	P25054	APC	P49841	GSK3B	S2799	S2794T	2794	Missense	distal	-5	no	6.612	6.901	EPSD	TCGA;ICGC;COSMIC	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	P25054	APC	P49841	GSK3B	S2799	Q2804P	2804	Missense	distal	5	no	6.612	7.588	EPSD	TCGA	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	P25054	APC	P49841	GSK3B	S2803	R2801W	2801	Missense	proximal	-2	no	6.932	7.138	EPSD	TCGA;ICGC;COSMIC	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	P25054	APC	P49841	GSK3B	S2803	Q2804P	2804	Missense	proximal	1	no	6.932	10.200	EPSD	TCGA	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	P25054	APC	P49841	GSK3B	S2822	T2823R	2823	Missense	proximal	1	no	7.525	8.396	EPSD	TCGA;ICGC;COSMIC	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	P25054	APC	P49841	GSK3B	S2822	D2817H	2817	Missense	distal	-5	no	7.525	7.419	EPSD	TCGA;ICGC;COSMIC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	P25054	APC	P49841	GSK3B	S2822	K2815R	2815	Missense	distal	-7	no	7.525	7.522	EPSD	TCGA;ICGC;COSMIC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	P25054	APC	P49841	GSK3B	S2826	T2823R	2823	Missense	distal	-3	no	8.803	8.947	EPSD	TCGA;ICGC;COSMIC	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	P25054	APC	P49841	GSK3B	S2830	T2823R	2823	Missense	distal	-7	no	6.059	6.050	EPSD	TCGA;ICGC;COSMIC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	Q99626	CDX2	P49841	GSK3B	S12	Y5C	5	Missense	distal	-7	no	6.474	6.469	EPSD	TCGA;ICGC;COSMIC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	Q99626	CDX2	P49841	GSK3B	S60	P61S	61	Missense	proximal	1	no	9.247	5.402	EPSD	TCGA;ICGC;COSMIC	6.007	Loss
CMGC_GSK_GSK3B_ST	Q99626	CDX2	P49841	GSK3B	S283	L288V	288	Missense	distal	5	no	10.073	9.899	PhosphoSitePlus	TCGA;ICGC;COSMIC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	Q99626	CDX2	P49841	GSK3B	S287	G294D	294	Missense	distal	7	no	7.105	7.139	EPSD	TCGA;ICGC;COSMIC	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	Q99626	CDX2	P49841	GSK3B	S287	L288V	288	Missense	proximal	1	no	7.105	6.974	EPSD	TCGA;ICGC;COSMIC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	Q99626	CDX2	P49841	GSK3B	S291	G294D	294	Missense	distal	3	no	7.019	7.070	EPSD	TCGA;ICGC;COSMIC	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	Q99626	CDX2	P49841	GSK3B	S291	S295P	295	Missense	distal	4	no	7.019	4.048	EPSD	TCGA;ICGC;COSMIC	6.007	Loss
CMGC_GSK_GSK3B_ST	Q99626	CDX2	P49841	GSK3B	S291	L288V	288	Missense	distal	-3	no	7.019	7.176	EPSD	TCGA;ICGC;COSMIC	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	Q99626	CDX2	P49841	GSK3B	S295	G294D	294	Missense	proximal	-1	no	7.049	6.982	EPSD	TCGA;ICGC;COSMIC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	Q99626	CDX2	P49841	GSK3B	S295	S295P	295	Missense	central	0	yes	7.049	0.000	EPSD	TCGA;ICGC;COSMIC	6.007	Loss
CMGC_GSK_GSK3B_ST	Q99626	CDX2	P49841	GSK3B	S295	L288V	288	Missense	distal	-7	no	7.049	7.070	EPSD	TCGA;ICGC;COSMIC	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	P17812	CTPS1	P49841	GSK3B	S21	G15E	15	Missense	distal	-6	no	6.157	6.079	EPSD	TCGA;COSMIC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	P17812	CTPS1	P49841	GSK3B	S210	R205K	205	Missense	distal	-5	no	7.051	6.554	EPSD	TCGA;COSMIC;GDSC;CCLE	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	P17812	CTPS1	P49841	GSK3B	S562	T566I	566	Missense	distal	4	no	7.706	5.253	EPSD	TCGA;ICGC;COSMIC	6.007	Loss
CMGC_GSK_GSK3B_ST	P17812	CTPS1	P49841	GSK3B	S571	T566I	566	Missense	distal	-5	no	8.812	8.995	PhosphoSitePlus	TCGA;ICGC;COSMIC	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	P17812	CTPS1	P49841	GSK3B	S571	P576H	576	Missense	distal	5	no	8.812	7.185	PhosphoSitePlus	TCGA;ICGC;COSMIC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	P17812	CTPS1	P49841	GSK3B	S574	P576H	576	Missense	proximal	2	no	7.509	6.740	EPSD	TCGA;ICGC;COSMIC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	P17812	CTPS1	P49841	GSK3B	S574	T581I	581	Missense	distal	7	no	7.509	7.903	EPSD	TCGA;ICGC	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	P17812	CTPS1	P49841	GSK3B	S575	P576H	576	Missense	proximal	1	no	9.324	5.624	EPSD	TCGA;ICGC;COSMIC	6.007	Loss
CMGC_GSK_GSK3B_ST	P17812	CTPS1	P49841	GSK3B	S575	E582K	582	Missense	distal	7	no	9.324	9.216	EPSD	TCGA;COSMIC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	P17812	CTPS1	P49841	GSK3B	S575	T581I	581	Missense	distal	6	no	9.324	9.322	EPSD	TCGA;ICGC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	P30291	WEE1	P49841	GSK3B	S289	M291R	291	Missense	proximal	2	no	5.418	6.008	EPSD	TCGA;ICGC;COSMIC	6.007	Gain
CMGC_GSK_GSK3B_ST	P30291	WEE1	P49841	GSK3B	S293	M291R	291	Missense	proximal	-2	no	6.714	6.930	EPSD	TCGA;ICGC;COSMIC	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	P30291	WEE1	P49841	GSK3B	S293	E298A	298	Missense	distal	5	no	6.714	6.331	EPSD	TCGA;COSMIC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	P30291	WEE1	P49841	GSK3B	S472	P473L	473	Missense	proximal	1	no	9.090	6.230	EPSD	TCGA;ICGC;COSMIC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	P30291	WEE1	P49841	GSK3B	S480	E486A	486	Missense	distal	6	no	6.217	6.221	EPSD	TCGA;ICGC;COSMIC	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	P30291	WEE1	P49841	GSK3B	S480	P473L	473	Missense	distal	-7	no	6.217	6.218	EPSD	TCGA;ICGC;COSMIC	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	P30291	WEE1	P49841	GSK3B	S480	L483F	483	Missense	distal	3	no	6.217	6.306	EPSD	TCGA;ICGC;COSMIC	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	Q14195	DPYSL3	P49841	GSK3B	T509	P510S	510	Missense	proximal	1	no	9.218	5.373	EPSD;PhosphoSitePlus	TCGA;COSMIC	6.007	Loss
CMGC_GSK_GSK3B_ST	Q14195	DPYSL3	P49841	GSK3B	T509	G513R	513	Missense	distal	4	no	9.218	9.423	EPSD;PhosphoSitePlus	TCGA;COSMIC	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	Q14195	DPYSL3	P49841	GSK3B	T514	P510S	510	Missense	distal	-4	no	10.212	10.775	PhosphoSitePlus;EPSD	TCGA;COSMIC	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	Q14195	DPYSL3	P49841	GSK3B	T514	G513R	513	Missense	proximal	-1	no	10.212	10.068	PhosphoSitePlus;EPSD	TCGA;COSMIC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	Q14195	DPYSL3	P49841	GSK3B	S518	G513R	513	Missense	distal	-5	no	9.273	9.504	EPSD;PhosphoSitePlus	TCGA;COSMIC	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	Q14195	DPYSL3	P49841	GSK3B	S522	P528S	528	Missense	distal	6	no	7.516	7.514	EPSD	TCGA;COSMIC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	Q14195	DPYSL3	P49841	GSK3B	T524	P528S	528	Missense	distal	4	no	5.724	8.695	EPSD	TCGA;COSMIC	6.007	Gain
CMGC_GSK_GSK3B_ST	P54252	ATXN3	P49841	GSK3B	S29	E32K	32	Missense	distal	3	no	8.285	8.178	EPSD	TCGA;ICGC;COSMIC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	P54252	ATXN3	P49841	GSK3B	S256	R251S	251	Missense	distal	-5	no	7.524	6.826	PhosphoSitePlus	TCGA;COSMIC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	Q15910	EZH2	P49841	GSK3B	S76	R78H	78	Missense	proximal	2	no	7.147	6.804	EPSD	TCGA;ICGC;COSMIC;GDSC;CCLE	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	Q9Y6H5	SNCAIP	P49841	GSK3B	S80	S80L	80	Missense	central	0	yes	6.090	0.000	EPSD	TCGA;COSMIC	6.007	Loss
CMGC_GSK_GSK3B_ST	Q9Y6H5	SNCAIP	P49841	GSK3B	S80	R74C	74	Missense	distal	-6	no	6.090	6.136	EPSD	TCGA;COSMIC	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	Q9Y6H5	SNCAIP	P49841	GSK3B	S211	P216S	216	Missense	distal	5	no	9.226	8.272	EPSD	TCGA;COSMIC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	Q9Y6H5	SNCAIP	P49841	GSK3B	S211	A205V	205	Missense	distal	-6	no	9.226	9.148	EPSD	TCGA;COSMIC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	Q9Y6H5	SNCAIP	P49841	GSK3B	S211	P212T	212	Missense	proximal	1	no	9.226	6.035	EPSD	TCGA;COSMIC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	Q9Y6H5	SNCAIP	P49841	GSK3B	S211	K214Q	214	Missense	distal	3	no	9.226	9.315	EPSD	TCGA;COSMIC	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	Q9Y6H5	SNCAIP	P49841	GSK3B	S211	H217Y	217	Missense	distal	6	no	9.226	9.230	EPSD	TCGA;COSMIC	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	Q9Y6H5	SNCAIP	P49841	GSK3B	S239	E235K	235	Missense	distal	-4	no	7.654	7.386	EPSD	TCGA;COSMIC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	Q9Y6H5	SNCAIP	P49841	GSK3B	S239	E237K	237	Missense	proximal	-2	no	7.654	7.622	EPSD	TCGA;COSMIC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	Q9Y6H5	SNCAIP	P49841	GSK3B	S239	S239L	239	Missense	central	0	yes	7.654	0.000	EPSD	TCGA;COSMIC	6.007	Loss
CMGC_GSK_GSK3B_ST	Q9Y6H5	SNCAIP	P49841	GSK3B	S239	P241S	241	Missense	proximal	2	no	7.654	7.210	EPSD	TCGA;COSMIC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	Q9Y6H5	SNCAIP	P49841	GSK3B	T387	R381C	381	Missense	distal	-6	no	7.225	7.271	EPSD	TCGA;COSMIC	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	Q9Y6H5	SNCAIP	P49841	GSK3B	T387	P388T	388	Missense	proximal	1	no	7.225	4.034	EPSD	TCGA;COSMIC	6.007	Loss
CMGC_GSK_GSK3B_ST	Q9Y6H5	SNCAIP	P49841	GSK3B	T387	N382T	382	Missense	distal	-5	no	7.225	7.806	EPSD	TCGA;COSMIC	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	Q9Y6H5	SNCAIP	P49841	GSK3B	T387	T383I	383	Missense	distal	-4	no	7.225	5.077	EPSD	TCGA;COSMIC	6.007	Loss
CMGC_GSK_GSK3B_ST	Q9Y6H5	SNCAIP	P49841	GSK3B	S552	P558L	558	Missense	distal	6	no	6.281	6.274	EPSD	TCGA;COSMIC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	Q9Y6H5	SNCAIP	P49841	GSK3B	S552	S559P	559	Missense	distal	7	no	6.281	6.217	EPSD	TCGA;COSMIC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	Q9Y6H5	SNCAIP	P49841	GSK3B	S552	S552L	552	Missense	central	0	yes	6.281	0.000	EPSD	TCGA;COSMIC;GDSC;CCLE	6.007	Loss
CMGC_GSK_GSK3B_ST	Q9Y6H5	SNCAIP	P49841	GSK3B	S556	P558L	558	Missense	proximal	2	no	10.517	10.133	PhosphoSitePlus	TCGA;COSMIC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	Q9Y6H5	SNCAIP	P49841	GSK3B	S556	S559P	559	Missense	distal	3	no	10.517	10.535	PhosphoSitePlus	TCGA;COSMIC	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	Q9Y6H5	SNCAIP	P49841	GSK3B	S556	S552L	552	Missense	distal	-4	no	10.517	9.167	PhosphoSitePlus	TCGA;COSMIC;GDSC;CCLE	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	Q9Y6H5	SNCAIP	P49841	GSK3B	S556	S562G	562	Missense	distal	6	no	10.517	10.514	PhosphoSitePlus	TCGA	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	Q9Y6H5	SNCAIP	P49841	GSK3B	S559	P558L	558	Missense	proximal	-1	no	8.228	8.097	EPSD	TCGA;COSMIC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	Q9Y6H5	SNCAIP	P49841	GSK3B	S559	S559P	559	Missense	central	0	yes	8.228	0.000	EPSD	TCGA;COSMIC	6.007	Loss
CMGC_GSK_GSK3B_ST	Q9Y6H5	SNCAIP	P49841	GSK3B	S559	S562G	562	Missense	distal	3	no	8.228	8.272	EPSD	TCGA	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	Q9Y6H5	SNCAIP	P49841	GSK3B	S560	P567S	567	Missense	distal	7	no	8.622	8.686	EPSD	TCGA;COSMIC	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	Q9Y6H5	SNCAIP	P49841	GSK3B	S560	P558L	558	Missense	proximal	-2	no	8.622	8.292	EPSD	TCGA;COSMIC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	Q9Y6H5	SNCAIP	P49841	GSK3B	S560	S559P	559	Missense	proximal	-1	no	8.622	8.679	EPSD	TCGA;COSMIC	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	Q9Y6H5	SNCAIP	P49841	GSK3B	S560	S562G	562	Missense	proximal	2	no	8.622	8.364	EPSD	TCGA	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	Q9Y6H5	SNCAIP	P49841	GSK3B	S562	S569F	569	Missense	distal	7	no	7.051	7.129	EPSD	TCGA;COSMIC	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	Q9Y6H5	SNCAIP	P49841	GSK3B	S562	P567S	567	Missense	distal	5	no	7.051	6.097	EPSD	TCGA;COSMIC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	Q9Y6H5	SNCAIP	P49841	GSK3B	S562	P558L	558	Missense	distal	-4	no	7.051	6.265	EPSD	TCGA;COSMIC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	Q9Y6H5	SNCAIP	P49841	GSK3B	S562	S559P	559	Missense	distal	-3	no	7.051	6.935	EPSD	TCGA;COSMIC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	Q9Y6H5	SNCAIP	P49841	GSK3B	S562	S562G	562	Missense	central	0	yes	7.051	0.000	EPSD	TCGA	6.007	Loss
CMGC_GSK_GSK3B_ST	Q9Y6H5	SNCAIP	P49841	GSK3B	S563	S569F	569	Missense	distal	6	no	7.617	7.604	EPSD	TCGA;COSMIC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	Q9Y6H5	SNCAIP	P49841	GSK3B	S563	R570I	570	Missense	distal	7	no	7.617	7.514	EPSD	TCGA;COSMIC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	Q9Y6H5	SNCAIP	P49841	GSK3B	S563	P567S	567	Missense	distal	4	no	7.617	10.588	EPSD	TCGA;COSMIC	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	Q9Y6H5	SNCAIP	P49841	GSK3B	S563	P558L	558	Missense	distal	-5	no	7.617	7.882	EPSD	TCGA;COSMIC	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	Q9Y6H5	SNCAIP	P49841	GSK3B	S563	S559P	559	Missense	distal	-4	no	7.617	7.053	EPSD	TCGA;COSMIC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	Q9Y6H5	SNCAIP	P49841	GSK3B	S563	S562G	562	Missense	proximal	-1	no	7.617	7.623	EPSD	TCGA	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	Q9Y6H5	SNCAIP	P49841	GSK3B	S565	S569F	569	Missense	distal	4	no	7.092	3.478	EPSD	TCGA;COSMIC	6.007	Loss
CMGC_GSK_GSK3B_ST	Q9Y6H5	SNCAIP	P49841	GSK3B	S565	R570I	570	Missense	distal	5	no	7.092	6.109	EPSD	TCGA;COSMIC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	Q9Y6H5	SNCAIP	P49841	GSK3B	S565	P567S	567	Missense	proximal	2	no	7.092	6.648	EPSD	TCGA;COSMIC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	Q9Y6H5	SNCAIP	P49841	GSK3B	S565	P558L	558	Missense	distal	-7	no	7.092	7.094	EPSD	TCGA;COSMIC	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	Q9Y6H5	SNCAIP	P49841	GSK3B	S565	S559P	559	Missense	distal	-6	no	7.092	7.113	EPSD	TCGA;COSMIC	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	Q9Y6H5	SNCAIP	P49841	GSK3B	S565	S562G	562	Missense	distal	-3	no	7.092	7.088	EPSD	TCGA	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	Q9Y6H5	SNCAIP	P49841	GSK3B	S566	S569F	569	Missense	distal	3	no	6.273	6.062	EPSD	TCGA;COSMIC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	Q9Y6H5	SNCAIP	P49841	GSK3B	S566	R570I	570	Missense	distal	4	no	6.273	5.989	EPSD	TCGA;COSMIC	6.007	Loss
CMGC_GSK_GSK3B_ST	Q9Y6H5	SNCAIP	P49841	GSK3B	S566	P567S	567	Missense	proximal	1	no	6.273	2.428	EPSD	TCGA;COSMIC	6.007	Loss
CMGC_GSK_GSK3B_ST	Q9Y6H5	SNCAIP	P49841	GSK3B	S566	S559P	559	Missense	distal	-7	no	6.273	6.271	EPSD	TCGA;COSMIC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	Q9Y6H5	SNCAIP	P49841	GSK3B	S566	S562G	562	Missense	distal	-4	no	6.273	5.845	EPSD	TCGA	6.007	Loss
CMGC_GSK_GSK3B_ST	Q9Y6H5	SNCAIP	P49841	GSK3B	S674	Q672E	672	Missense	proximal	-2	no	6.055	5.997	EPSD	TCGA;COSMIC	6.007	Loss
CMGC_GSK_GSK3B_ST	Q9Y6H5	SNCAIP	P49841	GSK3B	S674	L670R	670	Missense	distal	-4	no	6.055	6.219	EPSD	TCGA;COSMIC	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	Q9Y6H5	SNCAIP	P49841	GSK3B	S674	L667M	667	Missense	distal	-7	no	6.055	6.076	EPSD	TCGA;COSMIC	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	Q9Y6H5	SNCAIP	P49841	GSK3B	S676	Q672E	672	Missense	distal	-4	no	6.253	6.485	EPSD	TCGA;COSMIC	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	Q9Y6H5	SNCAIP	P49841	GSK3B	S676	L670R	670	Missense	distal	-6	no	6.253	6.197	EPSD	TCGA;COSMIC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	Q9Y6H5	SNCAIP	P49841	GSK3B	S678	Q672E	672	Missense	distal	-6	no	8.105	8.047	EPSD	TCGA;COSMIC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	Q9Y6H5	SNCAIP	P49841	GSK3B	S747	S749C	749	Missense	proximal	2	no	8.771	8.278	EPSD	TCGA;COSMIC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	Q9Y6H5	SNCAIP	P49841	GSK3B	S747	P748T	748	Missense	proximal	1	no	8.771	5.580	EPSD	TCGA	6.007	Loss
CMGC_GSK_GSK3B_ST	Q9Y6H5	SNCAIP	P49841	GSK3B	S747	T751I	751	Missense	distal	4	no	8.771	6.318	EPSD	TCGA;COSMIC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	Q9Y6H5	SNCAIP	P49841	GSK3B	S747	S740F	740	Missense	distal	-7	no	8.771	8.781	EPSD	TCGA;COSMIC	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	Q9Y6H5	SNCAIP	P49841	GSK3B	S747	D744N	744	Missense	distal	-3	no	8.771	8.630	EPSD	TCGA;COSMIC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	Q9Y6H5	SNCAIP	P49841	GSK3B	S747	P750S	750	Missense	distal	3	no	8.771	8.753	EPSD	TCGA;COSMIC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	Q9Y6H5	SNCAIP	P49841	GSK3B	S747	G745S	745	Missense	proximal	-2	no	8.771	8.888	EPSD	TCGA;COSMIC	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	Q9Y6H5	SNCAIP	P49841	GSK3B	S747	S752L	752	Missense	distal	5	no	8.771	8.444	EPSD	TCGA;COSMIC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	Q9Y6H5	SNCAIP	P49841	GSK3B	S747	S742F	742	Missense	distal	-5	no	8.771	9.331	EPSD	TCGA	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	Q9Y6H5	SNCAIP	P49841	GSK3B	S755	E756K	756	Missense	proximal	1	no	5.854	6.141	EPSD	TCGA;COSMIC	6.007	Gain
CMGC_GSK_GSK3B_ST	Q9Y6H5	SNCAIP	P49841	GSK3B	S755	P750S	750	Missense	distal	-5	no	5.854	6.010	EPSD	TCGA;COSMIC	6.007	Gain
CMGC_GSK_GSK3B_ST	Q02156	PRKCE	P49841	GSK3B	T228	V232L	232	Missense	distal	4	no	6.783	6.455	EPSD	TCGA;ICGC;COSMIC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	Q02156	PRKCE	P49841	GSK3B	S234	V232L	232	Missense	proximal	-2	no	7.285	7.244	EPSD	TCGA;ICGC;COSMIC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	Q02156	PRKCE	P49841	GSK3B	S234	R236G	236	Missense	proximal	2	no	7.285	7.008	EPSD	TCGA;ICGC;COSMIC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	Q02156	PRKCE	P49841	GSK3B	T309	D305Y	305	Missense	distal	-4	no	6.743	6.543	EPSD	TCGA;ICGC;COSMIC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	Q02156	PRKCE	P49841	GSK3B	T309	D305N	305	Missense	distal	-4	no	6.743	6.046	EPSD	TCGA;ICGC;COSMIC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	Q02156	PRKCE	P49841	GSK3B	T309	P310L	310	Missense	proximal	1	no	6.743	3.882	EPSD	TCGA;ICGC;COSMIC	6.007	Loss
CMGC_GSK_GSK3B_ST	Q02156	PRKCE	P49841	GSK3B	T309	V308I	308	Missense	proximal	-1	no	6.743	6.545	EPSD	TCGA;ICGC;COSMIC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	Q02156	PRKCE	P49841	GSK3B	T309	L306M	306	Missense	distal	-3	no	6.743	6.705	EPSD	TCGA;ICGC;COSMIC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	Q02156	PRKCE	P49841	GSK3B	S337	E341K	341	Missense	distal	4	no	6.387	5.205	EPSD	TCGA;ICGC;COSMIC	6.007	Loss
CMGC_GSK_GSK3B_ST	Q02156	PRKCE	P49841	GSK3B	S346	E341K	341	Missense	distal	-5	no	8.894	8.663	PhosphoSitePlus	TCGA;ICGC;COSMIC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	Q02156	PRKCE	P49841	GSK3B	S381	S388R	388	Missense	distal	7	no	5.657	6.095	EPSD	TCGA;ICGC;COSMIC	6.007	Gain
CMGC_GSK_GSK3B_ST	Q02156	PRKCE	P49841	GSK3B	S388	S381F	381	Missense	distal	-7	no	7.823	7.833	EPSD	TCGA;ICGC	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	Q02156	PRKCE	P49841	GSK3B	S388	S388R	388	Missense	central	0	yes	7.823	0.000	EPSD	TCGA;ICGC;COSMIC	6.007	Loss
CMGC_GSK_GSK3B_ST	Q02156	PRKCE	P49841	GSK3B	T710	E706Q	706	Missense	distal	-4	no	6.249	6.016	EPSD	TCGA;ICGC;COSMIC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	Q02156	PRKCE	P49841	GSK3B	T710	R704W	704	Missense	distal	-6	no	6.249	6.276	EPSD	TCGA;ICGC;COSMIC	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	Q02156	PRKCE	P49841	GSK3B	T710	P707L	707	Missense	distal	-3	no	6.249	6.375	EPSD	TCGA;ICGC;COSMIC	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	P10914	IRF1	P49841	GSK3B	T76	N80S	80	Missense	distal	4	no	3.360	6.970	EPSD	TCGA;ICGC;COSMIC	6.007	Gain
CMGC_GSK_GSK3B_ST	P10914	IRF1	P49841	GSK3B	S184	S184L	184	Missense	central	0	yes	6.540	0.000	PhosphoSitePlus	TCGA;ICGC;COSMIC	6.007	Loss
CMGC_GSK_GSK3B_ST	P10914	IRF1	P49841	GSK3B	S215	L209V	209	Missense	distal	-6	no	9.080	9.014	EPSD	TCGA;ICGC;COSMIC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	P10914	IRF1	P49841	GSK3B	S221	A223P	223	Missense	proximal	2	no	5.782	6.218	EPSD	TCGA;ICGC;COSMIC	6.007	Gain
CMGC_GSK_GSK3B_ST	P10914	IRF1	P49841	GSK3B	S282	D281H	281	Missense	proximal	-1	no	6.331	6.340	EPSD	TCGA;ICGC;COSMIC	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	P10914	IRF1	P49841	GSK3B	S282	I287T	287	Missense	distal	5	no	6.331	6.975	EPSD	TCGA;ICGC;COSMIC	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	P10914	IRF1	P49841	GSK3B	T311	I318M	318	Missense	distal	7	no	6.650	6.683	EPSD	TCGA;ICGC;COSMIC	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	Q9BYG3	NIFK	P49841	GSK3B	T223	T227N	227	Missense	distal	4	no	8.408	5.667	EPSD	TCGA;COSMIC	6.007	Loss
CMGC_GSK_GSK3B_ST	Q9BYG3	NIFK	P49841	GSK3B	S230	G232D	232	Missense	proximal	2	no	8.011	8.361	PhosphoSitePlus;EPSD	TCGA;COSMIC	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	Q9BYG3	NIFK	P49841	GSK3B	S230	T227N	227	Missense	distal	-3	no	8.011	7.891	PhosphoSitePlus;EPSD	TCGA;COSMIC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	Q9BYG3	NIFK	P49841	GSK3B	T234	G232D	232	Missense	proximal	-2	no	10.460	10.562	EPSD;PhosphoSitePlus	TCGA;COSMIC	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	Q9BYG3	NIFK	P49841	GSK3B	T234	T227N	227	Missense	distal	-7	no	10.460	10.439	EPSD;PhosphoSitePlus	TCGA;COSMIC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	Q9BYG3	NIFK	P49841	GSK3B	T238	G232D	232	Missense	distal	-6	no	7.813	7.772	EPSD	TCGA;COSMIC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	Q9BYG3	NIFK	P49841	GSK3B	T277	E272V	272	Missense	distal	-5	no	6.180	6.329	EPSD	TCGA;COSMIC	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	Q9BYG3	NIFK	P49841	GSK3B	T277	E276Q	276	Missense	proximal	-1	no	6.180	6.085	EPSD	TCGA;COSMIC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	Q9BYG3	NIFK	P49841	GSK3B	T277	R284Q	284	Missense	distal	7	no	6.180	5.832	EPSD	TCGA;COSMIC	6.007	Loss
CMGC_GSK_GSK3B_ST	Q9BYG3	NIFK	P49841	GSK3B	T279	E272V	272	Missense	distal	-7	no	10.617	10.606	EPSD	TCGA;COSMIC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	Q9BYG3	NIFK	P49841	GSK3B	T279	E276Q	276	Missense	distal	-3	no	10.617	10.634	EPSD	TCGA;COSMIC	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	Q9BYG3	NIFK	P49841	GSK3B	T279	R284Q	284	Missense	distal	5	no	10.617	10.278	EPSD	TCGA;COSMIC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	P16220	CREB1	P49841	GSK3B	T104	S103A	103	Missense	proximal	-1	no	6.437	6.282	EPSD	TCGA;COSMIC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	P16220	CREB1	P49841	GSK3B	S117	D116G	116	Missense	proximal	-1	no	8.249	8.316	EPSD	TCGA;COSMIC	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	P16220	CREB1	P49841	GSK3B	S117	Q112H	112	Missense	distal	-5	no	8.249	8.273	EPSD	TCGA;COSMIC	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	P16220	CREB1	P49841	GSK3B	S129	L128I	128	Missense	proximal	-1	no	7.644	7.570	PhosphoSitePlus	TCGA;COSMIC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	P40337	VHL	P49841	GSK3B	S68	S65W	65	Missense	distal	-3	no	7.731	7.830	PhosphoSitePlus	TCGA;ICGC;COSMIC;CCLE	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	P40337	VHL	P49841	GSK3B	S68	V74D	74	Missense	distal	6	no	7.731	7.733	PhosphoSitePlus	TCGA;ICGC;COSMIC	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	P40337	VHL	P49841	GSK3B	S80	S80R	80	Missense	central	0	yes	6.622	0.000	EPSD	TCGA;ICGC;COSMIC	6.007	Loss
CMGC_GSK_GSK3B_ST	P40337	VHL	P49841	GSK3B	S80	V74D	74	Missense	distal	-6	no	6.622	6.664	EPSD	TCGA;ICGC;COSMIC	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	P40337	VHL	P49841	GSK3B	S80	N78D	78	Missense	proximal	-2	no	6.622	6.835	EPSD	TCGA;ICGC;COSMIC	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	P40337	VHL	P49841	GSK3B	S80	P86L	86	Missense	distal	6	no	6.622	6.615	EPSD	TCGA;ICGC;COSMIC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	P40337	VHL	P49841	GSK3B	S80	N78Y	78	Missense	proximal	-2	no	6.622	6.531	EPSD	TCGA;ICGC;COSMIC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	P40337	VHL	P49841	GSK3B	S80	R82P	82	Missense	proximal	2	no	6.622	7.048	EPSD	TCGA;ICGC;COSMIC	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	P40337	VHL	P49841	GSK3B	S80	R79G	79	Missense	proximal	-1	no	6.622	6.766	EPSD	TCGA;ICGC;COSMIC	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	P40337	VHL	P49841	GSK3B	S168	L169P	169	Missense	proximal	1	no	4.503	7.363	EPSD	TCGA;ICGC;COSMIC	6.007	Gain
CMGC_GSK_GSK3B_ST	P40337	VHL	P49841	GSK3B	S183	L184P	184	Missense	proximal	1	no	3.235	6.096	EPSD	TCGA;COSMIC	6.007	Gain
CMGC_GSK_GSK3B_ST	Q9H0Z9	RBM38	P49841	GSK3B	S195	A197V	197	Missense	proximal	2	no	7.188	6.911	PhosphoSitePlus	TCGA	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	Q9H0Z9	RBM38	P49841	GSK3B	S195	S195L	195	Missense	central	0	yes	7.188	0.000	PhosphoSitePlus	TCGA;COSMIC	6.007	Loss
CMGC_GSK_GSK3B_ST	Q9H0Z9	RBM38	P49841	GSK3B	S195	Y192C	192	Missense	distal	-3	no	7.188	7.151	PhosphoSitePlus	TCGA;COSMIC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	Q9H0Z9	RBM38	P49841	GSK3B	S195	A194T	194	Missense	proximal	-1	no	7.188	7.267	PhosphoSitePlus	TCGA	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	Q9H0Z9	RBM38	P49841	GSK3B	S195	T198M	198	Missense	distal	3	no	7.188	7.030	PhosphoSitePlus	TCGA;COSMIC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	Q01201	RELB	P49841	GSK3B	S116	A118V	118	Missense	proximal	2	no	7.970	7.693	EPSD	TCGA;COSMIC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	Q01201	RELB	P49841	GSK3B	S116	P110L	110	Missense	distal	-6	no	7.970	7.948	EPSD	TCGA;COSMIC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	Q01201	RELB	P49841	GSK3B	S217	R213Q	213	Missense	distal	-4	no	8.605	8.962	EPSD	TCGA;COSMIC	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	Q01201	RELB	P49841	GSK3B	S217	R211Q	211	Missense	distal	-6	no	8.605	8.657	EPSD	TCGA;COSMIC;GDSC	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	Q01201	RELB	P49841	GSK3B	S425	S432I	432	Missense	distal	7	no	5.723	6.058	EPSD	TCGA;ICGC;COSMIC	6.007	Gain
CMGC_GSK_GSK3B_ST	Q01201	RELB	P49841	GSK3B	S573	A566V	566	Missense	distal	-7	no	9.095	9.094	PhosphoSitePlus	TCGA;ICGC;COSMIC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	Q04206	RELA	P49841	GSK3B	S316	G320E	320	Missense	distal	4	no	4.991	6.213	EPSD	TCGA;ICGC;COSMIC	6.007	Gain
CMGC_GSK_GSK3B_ST	Q04206	RELA	P49841	GSK3B	S335	A339T	339	Missense	distal	4	no	4.565	6.108	EPSD	TCGA;ICGC;COSMIC;CCLE	6.007	Gain
CMGC_GSK_GSK3B_ST	Q04206	RELA	P49841	GSK3B	S468	V469I	469	Missense	proximal	1	no	8.201	7.310	PhosphoSitePlus	TCGA;ICGC;COSMIC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	Q04206	RELA	P49841	GSK3B	T505	A507S	507	Missense	proximal	2	no	6.176	6.168	EPSD	TCGA	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	Q04206	RELA	P49841	GSK3B	T505	A507T	507	Missense	proximal	2	no	6.176	6.295	EPSD	TCGA;ICGC;COSMIC	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	Q04206	RELA	P49841	GSK3B	T505	E498D	498	Missense	distal	-7	no	6.176	6.146	EPSD	TCGA;ICGC;COSMIC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	Q04206	RELA	P49841	GSK3B	T505	E498K	498	Missense	distal	-7	no	6.176	6.165	EPSD	TCGA;ICGC;COSMIC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	P30279	CCND2	P49841	GSK3B	S271	E272D	272	Missense	proximal	1	no	5.729	6.459	EPSD	TCGA;ICGC	6.007	Gain
CMGC_GSK_GSK3B_ST	P30279	CCND2	P49841	GSK3B	T280	R285W	285	Missense	distal	5	no	9.037	7.735	PhosphoSitePlus	TCGA;ICGC;COSMIC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	P30279	CCND2	P49841	GSK3B	T280	D273N	273	Missense	distal	-7	no	9.037	9.040	PhosphoSitePlus	TCGA;ICGC;COSMIC	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	P30279	CCND2	P49841	GSK3B	T280	R285Q	285	Missense	distal	5	no	9.037	8.698	PhosphoSitePlus	TCGA;ICGC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	Q16555	DPYSL2	P49841	GSK3B	S292	A296S	296	Missense	distal	4	no	4.389	6.801	EPSD	TCGA;COSMIC	6.007	Gain
CMGC_GSK_GSK3B_ST	Q16555	DPYSL2	P49841	GSK3B	S304	F301V	301	Missense	distal	-3	no	10.759	10.859	EPSD	TCGA;COSMIC	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	Q16555	DPYSL2	P49841	GSK3B	S308	F301V	301	Missense	distal	-7	no	8.416	8.427	EPSD	TCGA;COSMIC	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	Q16555	DPYSL2	P49841	GSK3B	T509	V513I	513	Missense	distal	4	no	8.948	8.016	PhosphoSitePlus;EPSD	TCGA;COSMIC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	Q16555	DPYSL2	P49841	GSK3B	T509	T509M	509	Missense	central	0	yes	8.948	0.000	PhosphoSitePlus;EPSD	TCGA;COSMIC	6.007	Loss
CMGC_GSK_GSK3B_ST	Q16555	DPYSL2	P49841	GSK3B	T509	P515S	515	Missense	distal	6	no	8.948	8.946	PhosphoSitePlus;EPSD	TCGA;COSMIC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	Q16555	DPYSL2	P49841	GSK3B	T514	V513I	513	Missense	proximal	-1	no	10.797	10.599	EPSD;PhosphoSitePlus	TCGA;COSMIC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	Q16555	DPYSL2	P49841	GSK3B	T514	T509M	509	Missense	distal	-5	no	10.797	10.809	EPSD;PhosphoSitePlus	TCGA;COSMIC	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	Q16555	DPYSL2	P49841	GSK3B	T514	P515S	515	Missense	proximal	1	no	10.797	6.952	EPSD;PhosphoSitePlus	TCGA;COSMIC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	Q16555	DPYSL2	P49841	GSK3B	T514	T521M	521	Missense	distal	7	no	10.797	11.224	EPSD;PhosphoSitePlus	TCGA;COSMIC	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	Q16555	DPYSL2	P49841	GSK3B	S517	V513I	513	Missense	distal	-4	no	6.318	5.069	EPSD	TCGA;COSMIC	6.007	Loss
CMGC_GSK_GSK3B_ST	Q16555	DPYSL2	P49841	GSK3B	S517	P515S	515	Missense	proximal	-2	no	6.318	6.062	EPSD	TCGA;COSMIC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	Q16555	DPYSL2	P49841	GSK3B	S517	T521M	521	Missense	distal	4	no	6.318	4.952	EPSD	TCGA;COSMIC	6.007	Loss
CMGC_GSK_GSK3B_ST	Q16555	DPYSL2	P49841	GSK3B	S518	V513I	513	Missense	distal	-5	no	8.398	8.290	EPSD;PhosphoSitePlus	TCGA;COSMIC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	Q16555	DPYSL2	P49841	GSK3B	S518	P515S	515	Missense	distal	-3	no	8.398	8.515	EPSD;PhosphoSitePlus	TCGA;COSMIC	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	Q16555	DPYSL2	P49841	GSK3B	S518	T521M	521	Missense	distal	3	no	8.398	8.239	EPSD;PhosphoSitePlus	TCGA;COSMIC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	Q16555	DPYSL2	P49841	GSK3B	S522	P515S	515	Missense	distal	-7	no	7.344	7.346	EPSD	TCGA;COSMIC	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	Q16555	DPYSL2	P49841	GSK3B	S522	T521M	521	Missense	proximal	-1	no	7.344	7.369	EPSD	TCGA;COSMIC	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	Q08050	FOXM1	P49841	GSK3B	S582	L588I	588	Missense	distal	6	no	7.070	7.074	EPSD	TCGA;ICGC	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	P24385	CCND1	P49841	GSK3B	T286	P287R	287	Missense	proximal	1	no	8.992	6.672	PhosphoSitePlus	TCGA;ICGC;COSMIC;GDSC;CCLE	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	P24385	CCND1	P49841	GSK3B	T286	P287T	287	Missense	proximal	1	no	8.992	5.801	PhosphoSitePlus	TCGA;ICGC;COSMIC;CCLE	6.007	Loss
CMGC_GSK_GSK3B_ST	P24385	CCND1	P49841	GSK3B	T286	P287L	287	Missense	proximal	1	no	8.992	6.131	PhosphoSitePlus	TCGA;ICGC;COSMIC;GDSC;CCLE	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	P24385	CCND1	P49841	GSK3B	T286	D282H	282	Missense	distal	-4	no	8.992	8.504	PhosphoSitePlus	TCGA;ICGC;COSMIC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	P24385	CCND1	P49841	GSK3B	T286	V290M	290	Missense	distal	4	no	8.992	9.147	PhosphoSitePlus	TCGA;ICGC	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	P24385	CCND1	P49841	GSK3B	T286	P287H	287	Missense	proximal	1	no	8.992	5.291	PhosphoSitePlus	TCGA;ICGC;COSMIC	6.007	Loss
CMGC_GSK_GSK3B_ST	P24385	CCND1	P49841	GSK3B	T286	T286R	286	Missense	central	0	yes	8.992	0.000	PhosphoSitePlus	TCGA;ICGC;COSMIC	6.007	Loss
CMGC_GSK_GSK3B_ST	P24385	CCND1	P49841	GSK3B	T286	V293G	293	Missense	distal	7	no	8.992	8.586	PhosphoSitePlus	TCGA;ICGC;COSMIC;CCLE	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	P24385	CCND1	P49841	GSK3B	T286	T286I	286	Missense	central	0	yes	8.992	0.000	PhosphoSitePlus	TCGA;ICGC;COSMIC	6.007	Loss
CMGC_GSK_GSK3B_ST	P24385	CCND1	P49841	GSK3B	T286	P287S	287	Missense	proximal	1	no	8.992	5.147	PhosphoSitePlus	TCGA;ICGC;COSMIC	6.007	Loss
CMGC_GSK_GSK3B_ST	P24385	CCND1	P49841	GSK3B	T286	V281E	281	Missense	distal	-5	no	8.992	8.843	PhosphoSitePlus	TCGA;ICGC;COSMIC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	P24385	CCND1	P49841	GSK3B	T286	T286A	286	Missense	central	0	yes	8.992	0.000	PhosphoSitePlus	TCGA;ICGC;COSMIC	6.007	Loss
CMGC_GSK_GSK3B_ST	Q07817	BCL2L1	P49841	GSK3B	T47	A50V	50	Missense	distal	3	no	6.006	6.135	EPSD	TCGA;ICGC;COSMIC	6.007	Gain
CMGC_GSK_GSK3B_ST	Q07817	BCL2L1	P49841	GSK3B	T115	T109A	109	Missense	distal	-6	no	6.249	6.317	EPSD	TCGA;ICGC;COSMIC	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	Q07817	BCL2L1	P49841	GSK3B	T115	Q121P	121	Missense	distal	6	no	6.249	6.254	EPSD	TCGA;ICGC;COSMIC	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	Q07817	BCL2L1	P49841	GSK3B	T115	Q121H	121	Missense	distal	6	no	6.249	6.242	EPSD	TCGA;ICGC;COSMIC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	P41236	PPP1R2	P49841	GSK3B	S28	P32S	32	Missense	distal	4	no	3.295	6.266	EPSD	TCGA;ICGC;COSMIC	6.007	Gain
CMGC_GSK_GSK3B_ST	P41236	PPP1R2	P49841	GSK3B	T73	E70K	70	Missense	distal	-3	no	9.410	9.420	PhosphoSitePlus	TCGA;ICGC;COSMIC	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	P41236	PPP1R2	P49841	GSK3B	T177	A178T	178	Missense	proximal	1	no	6.008	6.549	EPSD	TCGA;ICGC;COSMIC	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	P41236	PPP1R2	P49841	GSK3B	T177	E176Q	176	Missense	proximal	-1	no	6.008	5.913	EPSD	TCGA;ICGC;COSMIC	6.007	Loss
CMGC_GSK_GSK3B_ST	Q16236	NFE2L2	P49841	GSK3B	T211	P214Q	214	Missense	distal	3	no	6.279	6.224	EPSD	TCGA;COSMIC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	Q16236	NFE2L2	P49841	GSK3B	S347	S347L	347	Missense	central	0	yes	8.774	0.000	PhosphoSitePlus;EPSD	TCGA;COSMIC	6.007	Loss
CMGC_GSK_GSK3B_ST	Q16236	NFE2L2	P49841	GSK3B	S347	G345S	345	Missense	proximal	-2	no	8.774	8.892	PhosphoSitePlus;EPSD	TCGA;COSMIC	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	Q16236	NFE2L2	P49841	GSK3B	S351	S347L	347	Missense	distal	-4	no	9.109	7.759	EPSD	TCGA;COSMIC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	Q16236	NFE2L2	P49841	GSK3B	S351	G345S	345	Missense	distal	-6	no	9.109	9.093	EPSD	TCGA;COSMIC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	Q16236	NFE2L2	P49841	GSK3B	S410	V417M	417	Missense	distal	7	no	6.994	6.937	EPSD	TCGA;COSMIC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	Q16236	NFE2L2	P49841	GSK3B	S410	S414N	414	Missense	distal	4	no	6.994	3.384	EPSD	TCGA;COSMIC;GDSC;CCLE	6.007	Loss
CMGC_GSK_GSK3B_ST	Q16236	NFE2L2	P49841	GSK3B	S410	P406L	406	Missense	distal	-4	no	6.994	6.207	EPSD	TCGA	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	Q16236	NFE2L2	P49841	GSK3B	S577	P575L	575	Missense	proximal	-2	no	8.123	7.793	EPSD	TCGA;COSMIC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	Q16236	NFE2L2	P49841	GSK3B	S577	D570N	570	Missense	distal	-7	no	8.123	8.127	EPSD	TCGA;COSMIC	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	Q16236	NFE2L2	P49841	GSK3B	S577	P575S	575	Missense	proximal	-2	no	8.123	7.867	EPSD	TCGA;COSMIC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	P13807	GYS1	P49841	GSK3B	S641	P644L	644	Missense	distal	3	no	12.074	11.756	EPSD	TCGA;COSMIC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	P13807	GYS1	P49841	GSK3B	S641	S647L	647	Missense	distal	6	no	12.074	12.069	EPSD	TCGA;COSMIC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	P13807	GYS1	P49841	GSK3B	S645	P644L	644	Missense	proximal	-1	no	12.415	12.283	EPSD;PhosphoSitePlus	TCGA;COSMIC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	P13807	GYS1	P49841	GSK3B	S645	S647L	647	Missense	proximal	2	no	12.415	12.475	EPSD;PhosphoSitePlus	TCGA;COSMIC	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	P13807	GYS1	P49841	GSK3B	S649	P644L	644	Missense	distal	-5	no	9.204	9.470	EPSD	TCGA;COSMIC	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	P13807	GYS1	P49841	GSK3B	S649	S647L	647	Missense	proximal	-2	no	9.204	9.130	EPSD	TCGA;COSMIC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	P13807	GYS1	P49841	GSK3B	S653	S647L	647	Missense	distal	-6	no	11.919	11.918	PhosphoSitePlus;EPSD	TCGA;COSMIC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	P13807	GYS1	P49841	GSK3B	S702	R695C	695	Missense	distal	-7	no	6.339	6.343	EPSD	TCGA;COSMIC	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	P13807	GYS1	P49841	GSK3B	S702	S698F	698	Missense	distal	-4	no	6.339	5.185	EPSD	TCGA;COSMIC	6.007	Loss
CMGC_GSK_GSK3B_ST	P13807	GYS1	P49841	GSK3B	S716	S720G	720	Missense	distal	4	no	6.141	2.897	EPSD	TCGA;COSMIC	6.007	Loss
CMGC_GSK_GSK3B_ST	P13807	GYS1	P49841	GSK3B	S716	L719I	719	Missense	distal	3	no	6.141	6.021	EPSD	TCGA;COSMIC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	P13807	GYS1	P49841	GSK3B	S717	S720G	720	Missense	distal	3	no	7.454	7.498	EPSD	TCGA;COSMIC	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	P13807	GYS1	P49841	GSK3B	S717	L719I	719	Missense	proximal	2	no	7.454	7.455	EPSD	TCGA;COSMIC	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	P13807	GYS1	P49841	GSK3B	S720	S720G	720	Missense	central	0	yes	6.874	0.000	EPSD	TCGA;COSMIC	6.007	Loss
CMGC_GSK_GSK3B_ST	P13807	GYS1	P49841	GSK3B	S720	L719I	719	Missense	proximal	-1	no	6.874	6.799	EPSD	TCGA;COSMIC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	P13807	GYS1	P49841	GSK3B	T721	S720G	720	Missense	proximal	-1	no	6.916	6.923	EPSD	TCGA;COSMIC	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	P13807	GYS1	P49841	GSK3B	T721	L719I	719	Missense	proximal	-2	no	6.916	6.979	EPSD	TCGA;COSMIC	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	P13807	GYS1	P49841	GSK3B	S723	S720G	720	Missense	distal	-3	no	6.798	6.794	EPSD	TCGA;COSMIC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	P13807	GYS1	P49841	GSK3B	S723	L719I	719	Missense	distal	-4	no	6.798	5.666	EPSD	TCGA;COSMIC	6.007	Loss
CMGC_GSK_GSK3B_ST	P13807	GYS1	P49841	GSK3B	S727	S720G	720	Missense	distal	-7	no	10.797	10.795	EPSD	TCGA;COSMIC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	P13807	GYS1	P49841	GSK3B	S727	G733C	733	Missense	distal	6	no	10.797	10.787	EPSD	TCGA;COSMIC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	P13807	GYS1	P49841	GSK3B	S731	G733C	733	Missense	proximal	2	no	7.096	6.862	EPSD	TCGA;COSMIC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	P49716	CEBPD	P49841	GSK3B	S191	G186D	186	Missense	distal	-5	no	6.452	6.259	EPSD	TCGA;ICGC;COSMIC;CCLE	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	P49716	CEBPD	P49841	GSK3B	S191	R195Q	195	Missense	distal	4	no	6.452	5.927	EPSD	TCGA;ICGC;COSMIC	6.007	Loss
CMGC_GSK_GSK3B_ST	P49716	CEBPD	P49841	GSK3B	S256	P257A	257	Missense	proximal	1	no	10.967	7.235	EPSD	TCGA;ICGC;COSMIC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	P49716	CEBPD	P49841	GSK3B	S256	P255L	255	Missense	proximal	-1	no	10.967	10.836	EPSD	TCGA;ICGC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	P13051	UNG	P49841	GSK3B	S12	P13H	13	Missense	proximal	1	no	7.468	3.768	EPSD	TCGA;ICGC;COSMIC	6.007	Loss
CMGC_GSK_GSK3B_ST	P13051	UNG	P49841	GSK3B	S12	F10V	10	Missense	proximal	-2	no	7.468	7.766	EPSD	TCGA;ICGC	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	P13051	UNG	P49841	GSK3B	S14	P13H	13	Missense	proximal	-1	no	7.637	7.529	EPSD	TCGA;ICGC;COSMIC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	P13051	UNG	P49841	GSK3B	S14	F10V	10	Missense	distal	-4	no	7.637	7.557	EPSD	TCGA;ICGC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	P13051	UNG	P49841	GSK3B	T60	G59R	59	Missense	proximal	-1	no	10.640	10.496	EPSD;PhosphoSitePlus	TCGA;COSMIC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	P13051	UNG	P49841	GSK3B	S63	G59R	59	Missense	distal	-4	no	6.113	5.354	EPSD	TCGA;COSMIC	6.007	Loss
CMGC_GSK_GSK3B_ST	P13051	UNG	P49841	GSK3B	S64	G59R	59	Missense	distal	-5	no	8.358	8.589	PhosphoSitePlus;EPSD	TCGA;COSMIC	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	P13051	UNG	P49841	GSK3B	S279	P278S	278	Missense	proximal	-1	no	8.076	8.020	EPSD	TCGA;COSMIC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	P13051	UNG	P49841	GSK3B	S279	G286R	286	Missense	distal	7	no	8.076	8.494	EPSD	TCGA	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	Q14494	NFE2L1	P49841	GSK3B	S116	A123T	123	Missense	distal	7	no	8.993	8.586	EPSD	TCGA;ICGC;COSMIC;CCLE	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	Q14494	NFE2L1	P49841	GSK3B	S379	L377F	377	Missense	proximal	-2	no	7.123	6.867	PhosphoSitePlus	TCGA;COSMIC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	Q14494	NFE2L1	P49841	GSK3B	S379	F375C	375	Missense	distal	-4	no	7.123	6.163	PhosphoSitePlus	TCGA;COSMIC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	Q14494	NFE2L1	P49841	GSK3B	S379	L377V	377	Missense	proximal	-2	no	7.123	7.165	PhosphoSitePlus	TCGA;COSMIC	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	Q14494	NFE2L1	P49841	GSK3B	S379	F375L	375	Missense	distal	-4	no	7.123	6.927	PhosphoSitePlus	TCGA	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	Q14494	NFE2L1	P49841	GSK3B	S498	S499P	499	Missense	proximal	1	no	5.373	9.218	EPSD	TCGA;COSMIC	6.007	Gain
CMGC_GSK_GSK3B_ST	Q14494	NFE2L1	P49841	GSK3B	S500	S493F	493	Missense	distal	-7	no	7.860	7.870	EPSD	TCGA;COSMIC	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	Q14494	NFE2L1	P49841	GSK3B	S500	S501F	501	Missense	proximal	1	no	7.860	7.474	EPSD	TCGA;COSMIC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	Q14494	NFE2L1	P49841	GSK3B	S500	S499P	499	Missense	proximal	-1	no	7.860	7.916	EPSD	TCGA;COSMIC	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	Q14494	NFE2L1	P49841	GSK3B	S501	S501F	501	Missense	central	0	yes	7.603	0.000	EPSD	TCGA;COSMIC	6.007	Loss
CMGC_GSK_GSK3B_ST	Q14494	NFE2L1	P49841	GSK3B	S501	S499P	499	Missense	proximal	-2	no	7.603	7.859	EPSD	TCGA;COSMIC	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	Q14494	NFE2L1	P49841	GSK3B	S502	S501F	501	Missense	proximal	-1	no	6.810	6.679	EPSD	TCGA;COSMIC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	Q14494	NFE2L1	P49841	GSK3B	S502	S499P	499	Missense	distal	-3	no	6.810	6.693	EPSD	TCGA;COSMIC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	Q14494	NFE2L1	P49841	GSK3B	S507	S501F	501	Missense	distal	-6	no	7.582	7.528	EPSD	TCGA;COSMIC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	Q14494	NFE2L1	P49841	GSK3B	S508	S501F	501	Missense	distal	-7	no	6.503	6.513	EPSD	TCGA;COSMIC	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	Q14494	NFE2L1	P49841	GSK3B	S734	Q741L	741	Missense	distal	7	no	6.182	6.078	EPSD	TCGA;COSMIC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	Q7KZI7	MARK2	P49841	GSK3B	T208	K205Q	205	Missense	distal	-3	no	6.055	6.061	EPSD	TCGA;COSMIC	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	Q7KZI7	MARK2	P49841	GSK3B	T208	K205N	205	Missense	distal	-3	no	6.055	5.937	EPSD	TCGA;COSMIC	6.007	Loss
CMGC_GSK_GSK3B_ST	Q7KZI7	MARK2	P49841	GSK3B	T208	P213L	213	Missense	distal	5	no	6.055	4.774	EPSD	TCGA;ICGC;COSMIC	6.007	Loss
CMGC_GSK_GSK3B_ST	Q7KZI7	MARK2	P49841	GSK3B	S212	K205Q	205	Missense	distal	-7	no	11.034	11.027	PhosphoSitePlus	TCGA;COSMIC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	Q7KZI7	MARK2	P49841	GSK3B	S212	K205N	205	Missense	distal	-7	no	11.034	11.018	PhosphoSitePlus	TCGA;COSMIC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	Q7KZI7	MARK2	P49841	GSK3B	S212	P213L	213	Missense	proximal	1	no	11.034	8.173	PhosphoSitePlus	TCGA;ICGC;COSMIC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	Q7KZI7	MARK2	P49841	GSK3B	S386	A388V	388	Missense	proximal	2	no	7.462	7.185	EPSD	TCGA;COSMIC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	Q7KZI7	MARK2	P49841	GSK3B	S386	S390Y	390	Missense	distal	4	no	7.462	3.949	EPSD	TCGA;ICGC;COSMIC	6.007	Loss
CMGC_GSK_GSK3B_ST	Q7KZI7	MARK2	P49841	GSK3B	S386	A388S	388	Missense	proximal	2	no	7.462	7.454	EPSD	TCGA;ICGC;COSMIC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	Q7KZI7	MARK2	P49841	GSK3B	S386	A388T	388	Missense	proximal	2	no	7.462	7.581	EPSD	TCGA;COSMIC	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	Q7KZI7	MARK2	P49841	GSK3B	S398	N402S	402	Missense	distal	4	no	4.090	7.700	EPSD	TCGA;ICGC;COSMIC	6.007	Gain
CMGC_GSK_GSK3B_ST	Q7KZI7	MARK2	P49841	GSK3B	S483	P487S	487	Missense	distal	4	no	3.305	6.276	EPSD	TCGA;COSMIC	6.007	Gain
CMGC_GSK_GSK3B_ST	Q7KZI7	MARK2	P49841	GSK3B	S511	S514Y	514	Missense	distal	3	no	8.993	8.570	EPSD	TCGA;COSMIC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	Q7KZI7	MARK2	P49841	GSK3B	S511	P509L	509	Missense	proximal	-2	no	8.993	8.662	EPSD	TCGA;COSMIC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	Q7KZI7	MARK2	P49841	GSK3B	S511	T515M	515	Missense	distal	4	no	8.993	7.627	EPSD	TCGA;COSMIC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	Q7KZI7	MARK2	P49841	GSK3B	T515	S514Y	514	Missense	proximal	-1	no	6.622	6.482	EPSD	TCGA;COSMIC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	Q7KZI7	MARK2	P49841	GSK3B	T515	P509L	509	Missense	distal	-6	no	6.622	6.600	EPSD	TCGA;COSMIC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	Q7KZI7	MARK2	P49841	GSK3B	T515	T515M	515	Missense	central	0	yes	6.622	0.000	EPSD	TCGA;COSMIC	6.007	Loss
CMGC_GSK_GSK3B_ST	Q7KZI7	MARK2	P49841	GSK3B	S519	S514Y	514	Missense	distal	-5	no	5.378	6.030	EPSD	TCGA;COSMIC	6.007	Gain
CMGC_GSK_GSK3B_ST	Q7KZI7	MARK2	P49841	GSK3B	S533	R528C	528	Missense	distal	-5	no	6.136	5.958	EPSD	TCGA;COSMIC	6.007	Loss
CMGC_GSK_GSK3B_ST	Q7KZI7	MARK2	P49841	GSK3B	S578	P582S	582	Missense	distal	4	no	3.512	6.483	EPSD	TCGA;COSMIC	6.007	Gain
CMGC_GSK_GSK3B_ST	Q7KZI7	MARK2	P49841	GSK3B	S595	T596P	596	Missense	proximal	1	no	4.368	7.559	EPSD	TCGA;COSMIC	6.007	Gain
CMGC_GSK_GSK3B_ST	Q7KZI7	MARK2	P49841	GSK3B	T616	G614D	614	Missense	proximal	-2	no	7.288	7.390	EPSD	TCGA;COSMIC	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	Q7KZI7	MARK2	P49841	GSK3B	T616	L611F	611	Missense	distal	-5	no	7.288	7.739	EPSD	TCGA;COSMIC	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	Q7KZI7	MARK2	P49841	GSK3B	T616	P620L	620	Missense	distal	4	no	7.288	7.542	EPSD	TCGA;COSMIC	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	Q7KZI7	MARK2	P49841	GSK3B	S698	T702M	702	Missense	distal	4	no	6.595	5.229	EPSD	TCGA;COSMIC	6.007	Loss
CMGC_GSK_GSK3B_ST	Q7KZI7	MARK2	P49841	GSK3B	S698	R694H	694	Missense	distal	-4	no	6.595	6.694	EPSD	TCGA	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	Q13887	KLF5	P49841	GSK3B	S303	P302Q	302	Missense	proximal	-1	no	12.612	12.450	PhosphoSitePlus	TCGA;ICGC;COSMIC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	Q13887	KLF5	P49841	GSK3B	S303	S307A	307	Missense	distal	4	no	12.612	10.201	PhosphoSitePlus	TCGA;ICGC;COSMIC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	Q13887	KLF5	P49841	GSK3B	S303	P301S	301	Missense	proximal	-2	no	12.612	12.356	PhosphoSitePlus	TCGA;ICGC;COSMIC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	Q13887	KLF5	P49841	GSK3B	S303	P309S	309	Missense	distal	6	no	12.612	12.610	PhosphoSitePlus	TCGA;ICGC;COSMIC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	Q13887	KLF5	P49841	GSK3B	S303	P304L	304	Missense	proximal	1	no	12.612	9.752	PhosphoSitePlus	TCGA;ICGC;COSMIC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	Q13887	KLF5	P49841	GSK3B	S441	S441N	441	Missense	central	0	yes	6.012	0.000	EPSD	TCGA;ICGC;COSMIC	6.007	Loss
CMGC_GSK_GSK3B_ST	Q13887	KLF5	P49841	GSK3B	S445	S441N	441	Missense	distal	-4	no	7.376	6.078	EPSD	TCGA;ICGC;COSMIC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	O15516	CLOCK	P49841	GSK3B	S8	S12L	12	Missense	distal	4	no	6.400	3.683	EPSD	TCGA;ICGC;COSMIC;GDSC;CCLE	6.007	Loss
CMGC_GSK_GSK3B_ST	O15516	CLOCK	P49841	GSK3B	S177	T172A	172	Missense	distal	-5	no	7.065	7.053	EPSD	TCGA;ICGC;COSMIC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	O15516	CLOCK	P49841	GSK3B	S177	T181A	181	Missense	distal	4	no	7.065	5.522	EPSD	TCGA;ICGC	6.007	Loss
CMGC_GSK_GSK3B_ST	O15516	CLOCK	P49841	GSK3B	S394	E397Q	397	Missense	distal	3	no	6.883	6.865	EPSD	TCGA;ICGC;COSMIC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	O15516	CLOCK	P49841	GSK3B	S394	E392K	392	Missense	proximal	-2	no	6.883	6.852	EPSD	TCGA;ICGC;COSMIC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	O15516	CLOCK	P49841	GSK3B	S427	S431A	431	Missense	distal	4	no	9.116	6.704	PhosphoSitePlus	TCGA;ICGC;COSMIC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	O15516	CLOCK	P49841	GSK3B	T429	S431A	431	Missense	proximal	2	no	7.798	7.805	EPSD	TCGA;ICGC;COSMIC	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	O15516	CLOCK	P49841	GSK3B	S433	S431A	431	Missense	proximal	-2	no	7.203	6.869	EPSD	TCGA;ICGC;COSMIC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	O15516	CLOCK	P49841	GSK3B	S437	S431A	431	Missense	distal	-6	no	7.996	8.007	EPSD	TCGA;ICGC;COSMIC	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	O15516	CLOCK	P49841	GSK3B	S437	H442Y	442	Missense	distal	5	no	7.996	7.670	EPSD	TCGA;ICGC;COSMIC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	O15516	CLOCK	P49841	GSK3B	T457	T459M	459	Missense	proximal	2	no	7.371	6.673	EPSD	TCGA;ICGC;COSMIC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	P10914	IRF1	P49841	GSK3B	T180	S184L	184	Missense	distal	4	no	11.204	8.486	PhosphoSitePlus	TCGA;ICGC;COSMIC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	P30281	CCND3	P49841	GSK3B	S133	I126M	126	Missense	distal	-7	no	8.166	8.159	EPSD	TCGA;COSMIC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	P30281	CCND3	P49841	GSK3B	S133	R135L	135	Missense	proximal	2	no	8.166	8.207	EPSD	TCGA;COSMIC	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	P30281	CCND3	P49841	GSK3B	S259	S263C	263	Missense	distal	4	no	7.159	1.026	EPSD	TCGA;COSMIC	6.007	Loss
CMGC_GSK_GSK3B_ST	P30281	CCND3	P49841	GSK3B	S259	Q260E	260	Missense	proximal	1	no	7.159	6.594	EPSD	TCGA;COSMIC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	P30281	CCND3	P49841	GSK3B	S259	T261S	261	Missense	proximal	2	no	7.159	7.033	EPSD	TCGA;ICGC;COSMIC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	P30281	CCND3	P49841	GSK3B	S259	A266V	266	Missense	distal	7	no	7.159	7.237	EPSD	TCGA;ICGC;COSMIC;GDSC	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	P30281	CCND3	P49841	GSK3B	S264	P265T	265	Missense	proximal	1	no	6.434	3.243	EPSD	TCGA;COSMIC	6.007	Loss
CMGC_GSK_GSK3B_ST	P30281	CCND3	P49841	GSK3B	S264	S263C	263	Missense	proximal	-1	no	6.434	6.398	EPSD	TCGA;COSMIC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	P30281	CCND3	P49841	GSK3B	S264	Q260E	260	Missense	distal	-4	no	6.434	6.667	EPSD	TCGA;COSMIC	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	P30281	CCND3	P49841	GSK3B	S264	T261S	261	Missense	distal	-3	no	6.434	6.410	EPSD	TCGA;ICGC;COSMIC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	P30281	CCND3	P49841	GSK3B	S264	A266V	266	Missense	proximal	2	no	6.434	6.158	EPSD	TCGA;ICGC;COSMIC;GDSC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	P30281	CCND3	P49841	GSK3B	S275	P278R	278	Missense	distal	3	no	6.457	6.068	EPSD	TCGA;COSMIC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	P30281	CCND3	P49841	GSK3B	S279	P278R	278	Missense	proximal	-1	no	7.717	7.524	EPSD	TCGA;COSMIC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	P30281	CCND3	P49841	GSK3B	S279	T283A	283	Missense	distal	4	no	7.717	6.175	EPSD	TCGA;ICGC;COSMIC;CCLE	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	P30281	CCND3	P49841	GSK3B	T283	P278R	278	Missense	distal	-5	no	7.524	8.378	PhosphoSitePlus	TCGA;COSMIC	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	P30281	CCND3	P49841	GSK3B	T283	T283A	283	Missense	central	0	yes	7.524	0.000	PhosphoSitePlus	TCGA;ICGC;COSMIC;CCLE	6.007	Loss
CMGC_GSK_GSK3B_ST	P30281	CCND3	P49841	GSK3B	T283	V287I	287	Missense	distal	4	no	7.524	6.592	PhosphoSitePlus	TCGA;COSMIC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	P53805	RCAN1	P49841	GSK3B	S148	A152S	152	Missense	distal	4	no	4.047	6.458	EPSD	TCGA;COSMIC	6.007	Gain
CMGC_GSK_GSK3B_ST	P53805	RCAN1	P49841	GSK3B	S163	S167Y	167	Missense	distal	4	no	12.223	8.710	PhosphoSitePlus	TCGA;COSMIC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	P53805	RCAN1	P49841	GSK3B	S163	L161Q	161	Missense	proximal	-2	no	12.223	12.252	PhosphoSitePlus	TCGA;COSMIC	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	P53805	RCAN1	P49841	GSK3B	S167	S167Y	167	Missense	central	0	yes	6.637	0.000	EPSD	TCGA;COSMIC	6.007	Loss
CMGC_GSK_GSK3B_ST	P53805	RCAN1	P49841	GSK3B	S167	L161Q	161	Missense	distal	-6	no	6.637	6.634	EPSD	TCGA;COSMIC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	P53805	RCAN1	P49841	GSK3B	T208	V213I	213	Missense	distal	5	no	6.191	6.026	EPSD	TCGA;COSMIC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	P53805	RCAN1	P49841	GSK3B	T208	V211M	211	Missense	distal	3	no	6.191	6.209	EPSD	TCGA;COSMIC	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	P53805	RCAN1	P49841	GSK3B	T208	A203T	203	Missense	distal	-5	no	6.191	6.203	EPSD	TCGA;COSMIC	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	P53805	RCAN1	P49841	GSK3B	T208	T208I	208	Missense	central	0	yes	6.191	0.000	EPSD	TCGA	6.007	Loss
CMGC_GSK_GSK3B_ST	O15033	AREL1	P49841	GSK3B	T343	S339C	339	Missense	distal	-4	no	8.880	6.766	EPSD	TCGA;ICGC;COSMIC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	O15033	AREL1	P49841	GSK3B	S358	P359S	359	Missense	proximal	1	no	7.688	3.844	EPSD	TCGA;ICGC;COSMIC	6.007	Loss
CMGC_GSK_GSK3B_ST	O15033	AREL1	P49841	GSK3B	S358	K360M	360	Missense	proximal	2	no	7.688	7.164	EPSD	TCGA;ICGC;COSMIC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	O15033	AREL1	P49841	GSK3B	S358	F362L	362	Missense	distal	4	no	7.688	8.585	EPSD	TCGA;ICGC;COSMIC	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	O15033	AREL1	P49841	GSK3B	S358	Y354H	354	Missense	distal	-4	no	7.688	7.401	EPSD	TCGA;ICGC;COSMIC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	O15033	AREL1	P49841	GSK3B	S358	F362I	362	Missense	distal	4	no	7.688	7.981	EPSD	TCGA;ICGC	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	O15033	AREL1	P49841	GSK3B	S358	V364E	364	Missense	distal	6	no	7.688	7.693	EPSD	TCGA;ICGC;COSMIC	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	P04198	MYCN	P49841	GSK3B	T58	T58M	58	Missense	central	0	yes	12.373	0.000	PhosphoSitePlus	TCGA;ICGC;COSMIC	6.007	Loss
CMGC_GSK_GSK3B_ST	P04198	MYCN	P49841	GSK3B	T58	T58K	58	Missense	central	0	yes	12.373	0.000	PhosphoSitePlus	TCGA;ICGC;COSMIC	6.007	Loss
CMGC_GSK_GSK3B_ST	P04198	MYCN	P49841	GSK3B	S287	R286C	286	Missense	proximal	-1	no	5.933	6.034	EPSD	TCGA;ICGC;COSMIC	6.007	Gain
CMGC_GSK_GSK3B_ST	P04198	MYCN	P49841	GSK3B	S287	R286S	286	Missense	proximal	-1	no	5.933	6.070	EPSD	TCGA;ICGC;COSMIC	6.007	Gain
CMGC_GSK_GSK3B_ST	P04198	MYCN	P49841	GSK3B	S287	R286H	286	Missense	proximal	-1	no	5.933	6.018	EPSD	TCGA;ICGC;COSMIC	6.007	Gain
CMGC_GSK_GSK3B_ST	P04198	MYCN	P49841	GSK3B	S355	R357H	357	Missense	proximal	2	no	7.011	6.667	EPSD	TCGA;ICGC;COSMIC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	P04198	MYCN	P49841	GSK3B	S355	K348N	348	Missense	distal	-7	no	7.011	6.995	EPSD	TCGA;ICGC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	P04198	MYCN	P49841	GSK3B	S371	P372L	372	Missense	proximal	1	no	9.672	6.812	EPSD	TCGA;ICGC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	P04198	MYCN	P49841	GSK3B	S371	S377T	377	Missense	distal	6	no	9.672	9.675	EPSD	TCGA;ICGC;COSMIC	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	P04198	MYCN	P49841	GSK3B	S371	R373Q	373	Missense	proximal	2	no	9.672	9.877	EPSD	TCGA;ICGC;COSMIC	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	P04198	MYCN	P49841	GSK3B	S375	P372L	372	Missense	distal	-3	no	5.954	6.081	EPSD	TCGA;ICGC	6.007	Gain
CMGC_GSK_GSK3B_ST	P04198	MYCN	P49841	GSK3B	S375	S377T	377	Missense	proximal	2	no	5.954	6.081	EPSD	TCGA;ICGC;COSMIC	6.007	Gain
CMGC_GSK_GSK3B_ST	P04198	MYCN	P49841	GSK3B	S375	R373Q	373	Missense	proximal	-2	no	5.954	6.025	EPSD	TCGA;ICGC;COSMIC	6.007	Gain
CMGC_GSK_GSK3B_ST	P98170	XIAP	P49841	GSK3B	T180	L179P	179	Missense	proximal	-1	no	7.708	7.839	PhosphoSitePlus	TCGA;ICGC;COSMIC	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	P98170	XIAP	P49841	GSK3B	T180	D175A	175	Missense	distal	-5	no	7.708	7.713	PhosphoSitePlus	TCGA;ICGC;COSMIC	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	P98170	XIAP	P49841	GSK3B	T359	R365I	365	Missense	distal	6	no	9.465	9.469	EPSD	TCGA;ICGC;CCLE	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	P98170	XIAP	P49841	GSK3B	T359	E357K	357	Missense	proximal	-2	no	9.465	9.434	EPSD	TCGA;ICGC;COSMIC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	P98170	XIAP	P49841	GSK3B	T359	L362P	362	Missense	distal	3	no	9.465	9.783	EPSD	TCGA;ICGC;COSMIC	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	P98170	XIAP	P49841	GSK3B	S361	L362P	362	Missense	proximal	1	no	4.165	7.025	EPSD	TCGA;ICGC;COSMIC	6.007	Gain
CMGC_GSK_GSK3B_ST	P54132	BLM	P49841	GSK3B	S53	S48F	48	Missense	distal	-5	no	5.461	6.021	EPSD	TCGA;ICGC;COSMIC	6.007	Gain
CMGC_GSK_GSK3B_ST	P54132	BLM	P49841	GSK3B	T114	D110N	110	Missense	distal	-4	no	6.548	5.851	EPSD	TCGA;ICGC;COSMIC	6.007	Loss
CMGC_GSK_GSK3B_ST	P54132	BLM	P49841	GSK3B	T121	T125P	125	Missense	distal	4	no	7.252	5.150	EPSD	TCGA;ICGC;COSMIC	6.007	Loss
CMGC_GSK_GSK3B_ST	P54132	BLM	P49841	GSK3B	T125	R132W	132	Missense	distal	7	no	5.911	6.020	EPSD	TCGA;ICGC;COSMIC	6.007	Gain
CMGC_GSK_GSK3B_ST	P54132	BLM	P49841	GSK3B	S131	T125P	125	Missense	distal	-6	no	5.966	6.045	EPSD	TCGA;ICGC;COSMIC	6.007	Gain
CMGC_GSK_GSK3B_ST	P54132	BLM	P49841	GSK3B	S131	R132W	132	Missense	proximal	1	no	5.966	6.184	EPSD	TCGA;ICGC;COSMIC	6.007	Gain
CMGC_GSK_GSK3B_ST	P54132	BLM	P49841	GSK3B	T171	S175I	175	Missense	distal	4	no	8.317	4.995	PhosphoSitePlus	TCGA;ICGC;COSMIC	6.007	Loss
CMGC_GSK_GSK3B_ST	P54132	BLM	P49841	GSK3B	S304	S310C	310	Missense	distal	6	no	7.653	7.639	EPSD	TCGA;ICGC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	P54132	BLM	P49841	GSK3B	S304	F300C	300	Missense	distal	-4	no	7.653	6.692	EPSD	TCGA;ICGC;COSMIC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	P54132	BLM	P49841	GSK3B	S312	S310C	310	Missense	proximal	-2	no	6.066	5.755	EPSD	TCGA;ICGC	6.007	Loss
CMGC_GSK_GSK3B_ST	P54132	BLM	P49841	GSK3B	S316	S310C	310	Missense	distal	-6	no	6.978	6.966	EPSD	TCGA;ICGC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	P54132	BLM	P49841	GSK3B	S422	R429K	429	Missense	distal	7	no	6.516	6.008	EPSD	TCGA;ICGC;COSMIC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	P54132	BLM	P49841	GSK3B	S422	D420G	420	Missense	proximal	-2	no	6.516	6.414	EPSD	TCGA;ICGC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	P54132	BLM	P49841	GSK3B	S456	S449Y	449	Missense	distal	-7	no	5.998	6.027	EPSD	TCGA;ICGC	6.007	Gain
CMGC_GSK_GSK3B_ST	P54132	BLM	P49841	GSK3B	S601	L600F	600	Missense	proximal	-1	no	6.085	6.030	EPSD	TCGA;ICGC;COSMIC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	P54132	BLM	P49841	GSK3B	S706	C704R	704	Missense	proximal	-2	no	7.890	8.086	EPSD	TCGA	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	P54132	BLM	P49841	GSK3B	S714	P715L	715	Missense	proximal	1	no	11.395	8.534	EPSD	TCGA;ICGC;COSMIC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	P54132	BLM	P49841	GSK3B	S1138	G1134E	1134	Missense	distal	-4	no	6.050	5.881	EPSD	TCGA;ICGC;COSMIC	6.007	Loss
CMGC_GSK_GSK3B_ST	P54132	BLM	P49841	GSK3B	S1138	R1144I	1144	Missense	distal	6	no	6.050	6.054	EPSD	TCGA;ICGC;COSMIC	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	P54132	BLM	P49841	GSK3B	S1138	L1145R	1145	Missense	distal	7	no	6.050	6.502	EPSD	TCGA;ICGC	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	P54132	BLM	P49841	GSK3B	S1138	E1143K	1143	Missense	distal	5	no	6.050	5.183	EPSD	TCGA;ICGC;COSMIC	6.007	Loss
CMGC_GSK_GSK3B_ST	P54132	BLM	P49841	GSK3B	S1138	G1132V	1132	Missense	distal	-6	no	6.050	5.967	EPSD	TCGA;ICGC;COSMIC	6.007	Loss
CMGC_GSK_GSK3B_ST	P54132	BLM	P49841	GSK3B	S1252	D1256E	1256	Missense	distal	4	no	5.804	6.207	EPSD	TCGA;ICGC;COSMIC	6.007	Gain
CMGC_GSK_GSK3B_ST	P54132	BLM	P49841	GSK3B	S1286	S1280L	1280	Missense	distal	-6	no	6.378	6.377	EPSD	TCGA;ICGC;COSMIC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	P54132	BLM	P49841	GSK3B	S1304	G1308R	1308	Missense	distal	4	no	5.961	6.167	EPSD	TCGA;ICGC;COSMIC	6.007	Gain
CMGC_GSK_GSK3B_ST	P54132	BLM	P49841	GSK3B	S1390	Q1387E	1387	Missense	distal	-3	no	6.067	6.051	EPSD	TCGA;ICGC;COSMIC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	P54132	BLM	P49841	GSK3B	S1390	A1388T	1388	Missense	proximal	-2	no	6.067	6.429	EPSD	TCGA;ICGC;COSMIC	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	E9PAV3	NACA	P49841	GSK3B	S340	D333H	333	Missense	distal	-7	no	6.490	6.506	EPSD	TCGA;ICGC;COSMIC	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	E9PAV3	NACA	P49841	GSK3B	S340	D342Y	342	Missense	proximal	2	no	6.490	6.166	EPSD	TCGA;ICGC;COSMIC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	E9PAV3	NACA	P49841	GSK3B	S506	P510S	510	Missense	distal	4	no	6.061	9.032	EPSD	TCGA;ICGC;COSMIC	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	E9PAV3	NACA	P49841	GSK3B	S575	P571T	571	Missense	distal	-4	no	7.239	7.467	EPSD	TCGA;ICGC;COSMIC	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	E9PAV3	NACA	P49841	GSK3B	S575	S570P	570	Missense	distal	-5	no	7.239	7.082	EPSD	TCGA;ICGC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	E9PAV3	NACA	P49841	GSK3B	S579	L584F	584	Missense	distal	5	no	6.972	6.631	EPSD	TCGA;ICGC;COSMIC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	E9PAV3	NACA	P49841	GSK3B	S585	L584F	584	Missense	proximal	-1	no	9.009	8.954	EPSD	TCGA;ICGC;COSMIC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	Q92837	FRAT1	P49841	GSK3B	S249	R251H	251	Missense	proximal	2	no	7.700	7.357	EPSD	TCGA;ICGC;COSMIC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	Q92837	FRAT1	P49841	GSK3B	S249	S249P	249	Missense	central	0	yes	7.700	0.000	EPSD	TCGA;ICGC;COSMIC	6.007	Loss
CAMK_MAPKAPK_MK2_MAPKAPK3_ST	Q8N5C8	TAB3	Q16644	MAPKAPK3	S103	Q110R	110	Missense	distal	7	no	0.014	0.013	EPSD	TCGA;ICGC	0.011	Down-regulation
CAMK_MAPKAPK_MK2_MAPKAPK3_ST	Q8N5C8	TAB3	Q16644	MAPKAPK3	S356	T354S	354	Missense	proximal	-2	no	0.009	0.016	EPSD	TCGA;ICGC;COSMIC	0.011	Gain
CAMK_MAPKAPK_MK2_MAPKAPK3_ST	Q8N5C8	TAB3	Q16644	MAPKAPK3	S385	R382K	382	Missense	distal	-3	no	0.029	0.015	EPSD	TCGA;ICGC;COSMIC	0.011	Down-regulation
CAMK_MAPKAPK_MK2_MAPKAPK3_ST	Q8N5C8	TAB3	Q16644	MAPKAPK3	S411	S411L	411	Missense	central	0	yes	0.013	0.000	EPSD	TCGA;ICGC;COSMIC	0.011	Loss
CAMK_MAPKAPK_MK2_MAPKAPK3_ST	Q8N5C8	TAB3	Q16644	MAPKAPK3	S411	P410L	410	Missense	proximal	-1	no	0.013	0.014	EPSD	TCGA;ICGC;COSMIC	0.011	Up-regulation
CAMK_MAPKAPK_MK2_MAPKAPK3_ST	Q8N5C8	TAB3	Q16644	MAPKAPK3	S411	S409F	409	Missense	proximal	-2	no	0.013	0.009	EPSD	TCGA;ICGC;COSMIC	0.011	Loss
CAMK_MAPKAPK_MK2_MAPKAPK3_ST	Q8N5C8	TAB3	Q16644	MAPKAPK3	S415	P410L	410	Missense	distal	-5	no	0.023	0.025	EPSD	TCGA;ICGC;COSMIC	0.011	Up-regulation
CAMK_MAPKAPK_MK2_MAPKAPK3_ST	Q8N5C8	TAB3	Q16644	MAPKAPK3	S415	S415C	415	Missense	central	0	yes	0.023	0.000	EPSD	TCGA;ICGC;COSMIC	0.011	Loss
CAMK_MAPKAPK_MK2_MAPKAPK3_ST	Q8N5C8	TAB3	Q16644	MAPKAPK3	S415	P421T	421	Missense	distal	6	no	0.023	0.024	EPSD	TCGA;ICGC	0.011	Up-regulation
CAMK_MAPKAPK_MK2_MAPKAPK3_ST	Q8N5C8	TAB3	Q16644	MAPKAPK3	S509	Y514C	514	Missense	distal	5	no	0.011	0.012	EPSD	TCGA;ICGC;COSMIC	0.011	Up-regulation
CAMK_MAPKAPK_MK2_MAPKAPK3_ST	Q8N5C8	TAB3	Q16644	MAPKAPK3	S509	Y514H	514	Missense	distal	5	no	0.011	0.012	EPSD	TCGA;ICGC;COSMIC	0.011	Up-regulation
CAMK_MAPKAPK_MK2_MAPKAPK3_ST	Q8N5C8	TAB3	Q16644	MAPKAPK3	S563	S563C	563	Missense	central	0	yes	0.021	0.000	EPSD	TCGA;COSMIC	0.011	Loss
CAMK_MAPKAPK_MK2_MAPKAPK3_ST	Q8N5C8	TAB3	Q16644	MAPKAPK3	S563	R560I	560	Missense	distal	-3	no	0.021	0.006	EPSD	TCGA;COSMIC	0.011	Loss
CAMK_MAPKAPK_MK2_MAPKAPK3_ST	Q8N5C8	TAB3	Q16644	MAPKAPK3	S645	R642Q	642	Missense	distal	-3	no	0.022	0.008	EPSD	TCGA;ICGC;COSMIC	0.011	Loss
CAMK_MAPKAPK_MK2_MAPKAPK3_ST	Q8N5C8	TAB3	Q16644	MAPKAPK3	S645	A641T	641	Missense	distal	-4	no	0.022	0.021	EPSD	TCGA;ICGC;COSMIC	0.011	Down-regulation
CAMK_MAPKAPK_MK2_MAPKAPK3_ST	Q8N5C8	TAB3	Q16644	MAPKAPK3	S669	T670S	670	Missense	proximal	1	no	0.021	0.020	EPSD	TCGA;ICGC;COSMIC	0.011	Down-regulation
CAMK_MAPKAPK_MK2_MAPKAPK3_ST	Q8N5C8	TAB3	Q16644	MAPKAPK3	S669	R674Q	674	Missense	distal	5	no	0.021	0.020	EPSD	TCGA;ICGC;COSMIC;GDSC;CCLE	0.011	Down-regulation
CAMK_MAPKAPK_MK2_MAPKAPK3_ST	Q8N5C8	TAB3	Q16644	MAPKAPK3	S669	R666Q	666	Missense	distal	-3	no	0.021	0.006	EPSD	TCGA;ICGC;COSMIC	0.011	Loss
CAMK_MAPKAPK_MK2_MAPKAPK3_ST	Q14457	BECN1	Q16644	MAPKAPK3	S295	R292H	292	Missense	distal	-3	no	0.023	0.009	EPSD	TCGA;ICGC	0.011	Loss
CAMK_MAPKAPK_MK2_MAPKAPK3_ST	Q14457	BECN1	Q16644	MAPKAPK3	S414	G411S	411	Missense	distal	-3	no	0.012	0.010	EPSD	TCGA;ICGC;COSMIC	0.011	Loss
TK_Tec_BMX_Y	Q05397	PTK2	P51813	BMX	Y194	V201I	201	Missense	distal	7	no	5.195	5.216	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	2.549	Up-regulation
TK_Tec_BMX_Y	Q05397	PTK2	P51813	BMX	Y441	A448T	448	Missense	distal	7	no	5.381	5.390	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	2.549	Up-regulation
TK_Tec_BMX_Y	Q05397	PTK2	P51813	BMX	Y441	V436I	436	Missense	distal	-5	no	5.381	5.206	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	2.549	Down-regulation
TK_Tec_BMX_Y	Q05397	PTK2	P51813	BMX	Y441	A448D	448	Missense	distal	7	no	5.381	5.465	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	2.549	Up-regulation
TK_Tec_BMX_Y	Q05397	PTK2	P51813	BMX	Y742	N740D	740	Missense	proximal	-2	no	4.849	4.434	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	2.549	Down-regulation
TK_Tec_BMX_Y	Q05397	PTK2	P51813	BMX	Y742	N740K	740	Missense	proximal	-2	no	4.849	4.719	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	2.549	Down-regulation
TK_Tec_BMX_Y	Q05397	PTK2	P51813	BMX	Y742	N740S	740	Missense	proximal	-2	no	4.849	4.549	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	2.549	Down-regulation
TK_Tec_BMX_Y	Q05397	PTK2	P51813	BMX	Y861	I860M	860	Missense	proximal	-1	no	4.819	4.821	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	2.549	Up-regulation
TK_Tec_BMX_Y	Q05397	PTK2	P51813	BMX	Y861	P867S	867	Missense	distal	6	no	4.819	4.815	EPSD;PhosphoSitePlus	TCGA;ICGC	2.549	Down-regulation
TK_Tec_BMX_Y	Q05397	PTK2	P51813	BMX	Y861	H859R	859	Missense	proximal	-2	no	4.819	4.650	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	2.549	Down-regulation
TK_Tec_BMX_Y	Q07912	TNK2	P51813	BMX	Y518	G511D	511	Missense	distal	-7	no	2.468	2.674	EPSD	TCGA;COSMIC	2.549	Gain
TK_Tec_BMX_Y	Q07912	TNK2	P51813	BMX	Y518	G511S	511	Missense	distal	-7	no	2.468	2.852	EPSD	TCGA;COSMIC	2.549	Gain
TK_Tec_BMX_Y	Q07912	TNK2	P51813	BMX	Y860	S867A	867	Missense	distal	7	no	4.769	4.756	PhosphoSitePlus;EPSD	TCGA;COSMIC	2.549	Down-regulation
TK_Tec_BMX_Y	Q16611	BAK1	P51813	BMX	Y108	E109K	109	Missense	proximal	1	no	4.703	4.721	PhosphoSitePlus	TCGA;ICGC;COSMIC	2.549	Up-regulation
TK_Tec_BMX_Y	Q16611	BAK1	P51813	BMX	Y108	Y110H	110	Missense	proximal	2	no	4.703	4.731	PhosphoSitePlus	TCGA;ICGC;COSMIC	2.549	Up-regulation
TK_Tec_BMX_Y	Q96T51	RUFY1	P51813	BMX	Y389	Y389C	389	Missense	central	0	yes	4.671	0.000	PhosphoSitePlus;EPSD	TCGA	2.549	Loss
Other_PLK_PLK2_PLK2_ST	Q9HC77	CENPJ	Q9NYY3	PLK2	S471	L468I	468	Missense	distal	-3	no	15.349	14.395	EPSD	TCGA;ICGC;COSMIC	13.807	Down-regulation
Other_PLK_PLK2_PLK2_ST	Q9HC77	CENPJ	Q9NYY3	PLK2	S471	I475M	475	Missense	distal	4	no	15.349	16.077	EPSD	TCGA;ICGC	13.807	Up-regulation
Other_PLK_PLK2_PLK2_ST	Q9HC77	CENPJ	Q9NYY3	PLK2	S551	M546I	546	Missense	distal	-5	no	13.641	15.373	EPSD	TCGA;ICGC;COSMIC	13.807	Gain
Other_PLK_PLK2_PLK2_ST	Q9HC77	CENPJ	Q9NYY3	PLK2	S589	S589L	589	Missense	central	0	yes	21.223	0.000	PhosphoSitePlus;EPSD	TCGA;ICGC;COSMIC	13.807	Loss
Other_PLK_PLK2_PLK2_ST	Q9HC77	CENPJ	Q9NYY3	PLK2	S589	A584V	584	Missense	distal	-5	no	21.223	19.305	PhosphoSitePlus;EPSD	TCGA;ICGC;COSMIC	13.807	Down-regulation
Other_PLK_PLK2_PLK2_ST	Q9HC77	CENPJ	Q9NYY3	PLK2	S589	D586H	586	Missense	distal	-3	no	21.223	19.857	PhosphoSitePlus;EPSD	TCGA;ICGC;COSMIC	13.807	Down-regulation
Other_PLK_PLK2_PLK2_ST	Q9HC77	CENPJ	Q9NYY3	PLK2	S589	F590L	590	Missense	proximal	1	no	21.223	19.176	PhosphoSitePlus;EPSD	TCGA;ICGC	13.807	Down-regulation
Other_PLK_PLK2_PLK2_ST	Q9HC77	CENPJ	Q9NYY3	PLK2	S595	S589L	589	Missense	distal	-6	no	21.652	21.107	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	13.807	Down-regulation
Other_PLK_PLK2_PLK2_ST	Q9HC77	CENPJ	Q9NYY3	PLK2	S595	F590L	590	Missense	distal	-5	no	21.652	20.431	EPSD;PhosphoSitePlus	TCGA;ICGC	13.807	Down-regulation
Other_PLK_PLK2_PLK2_ST	Q9HC77	CENPJ	Q9NYY3	PLK2	S663	L667F	667	Missense	distal	4	no	14.657	15.267	EPSD	TCGA;ICGC;COSMIC	13.807	Up-regulation
Other_PLK_PLK2_PLK2_ST	Q9HC77	CENPJ	Q9NYY3	PLK2	S759	D755N	755	Missense	distal	-4	no	16.334	18.075	EPSD	TCGA;ICGC;COSMIC	13.807	Up-regulation
Other_PLK_PLK2_PLK2_ST	Q9HC77	CENPJ	Q9NYY3	PLK2	S787	D794Y	794	Missense	distal	7	no	15.002	14.080	EPSD	TCGA;ICGC;COSMIC	13.807	Down-regulation
Other_PLK_PLK2_PLK2_ST	Q9HC77	CENPJ	Q9NYY3	PLK2	S789	D794Y	794	Missense	distal	5	no	15.984	15.775	EPSD	TCGA;ICGC;COSMIC	13.807	Down-regulation
Other_PLK_PLK2_PLK2_ST	Q9HC77	CENPJ	Q9NYY3	PLK2	S1081	S1075P	1075	Missense	distal	-6	no	14.567	14.027	EPSD	TCGA;ICGC;COSMIC	13.807	Down-regulation
Other_PLK_PLK2_PLK2_ST	O15350	TP73	Q9NYY3	PLK2	S48	G44V	44	Missense	distal	-4	no	17.945	19.914	PhosphoSitePlus	TCGA;ICGC;COSMIC	13.807	Up-regulation
Other_PLK_PLK2_PLK2_ST	O15350	TP73	Q9NYY3	PLK2	S48	T45M	45	Missense	distal	-3	no	17.945	17.515	PhosphoSitePlus	TCGA	13.807	Down-regulation
Other_PLK_PLK2_PLK2_ST	O15350	TP73	Q9NYY3	PLK2	S48	V51I	51	Missense	distal	3	no	17.945	19.357	PhosphoSitePlus	TCGA;ICGC	13.807	Up-regulation
Other_PLK_PLK2_PLK2_ST	O15350	TP73	Q9NYY3	PLK2	S48	M49T	49	Missense	proximal	1	no	17.945	14.429	PhosphoSitePlus	TCGA;ICGC;COSMIC	13.807	Down-regulation
Other_PLK_PLK2_PLK2_ST	O15350	TP73	Q9NYY3	PLK2	S471	A472T	472	Missense	proximal	1	no	15.653	13.884	EPSD	TCGA;COSMIC;GDSC;CCLE	13.807	Down-regulation
Other_PLK_PLK2_PLK2_ST	P62258	YWHAE	Q9NYY3	PLK2	S59	A58T	58	Missense	proximal	-1	no	13.765	13.884	EPSD	TCGA;ICGC	13.807	Gain
Other_PLK_PLK2_PLK2_ST	P62258	YWHAE	Q9NYY3	PLK2	S148	Y152C	152	Missense	distal	4	no	15.332	12.116	EPSD	TCGA;COSMIC	13.807	Loss
Other_PLK_PLK2_PLK2_ST	P62258	YWHAE	Q9NYY3	PLK2	S148	R141K	141	Missense	distal	-7	no	15.332	16.151	EPSD	TCGA;COSMIC;GDSC;CCLE	13.807	Up-regulation
Other_PLK_PLK2_PLK2_ST	P62258	YWHAE	Q9NYY3	PLK2	T208	T208K	208	Missense	central	0	yes	18.895	0.000	PhosphoSitePlus	TCGA	13.807	Loss
Other_PLK_PLK2_PLK2_ST	P62258	YWHAE	Q9NYY3	PLK2	S233	G239S	239	Missense	distal	6	no	11.775	16.031	EPSD	TCGA	13.807	Gain
Other_PLK_PLK2_PLK2_ST	P06748	NPM1	Q9NYY3	PLK2	S106	S106L	106	Missense	central	0	yes	15.403	0.000	EPSD	TCGA;ICGC;COSMIC	13.807	Loss
Other_PLK_PLK2_PLK2_ST	P06748	NPM1	Q9NYY3	PLK2	S195	I196V	196	Missense	proximal	1	no	15.008	18.629	EPSD	TCGA;ICGC;COSMIC	13.807	Up-regulation
Other_PLK_PLK2_PLK2_ST	P06748	NPM1	Q9NYY3	PLK2	S260	K257E	257	Missense	distal	-3	no	14.641	15.981	EPSD	TCGA;ICGC;COSMIC	13.807	Up-regulation
Other_PLK_PLK2_PLK2_ST	P06748	NPM1	Q9NYY3	PLK2	S260	A266T	266	Missense	distal	6	no	14.641	13.627	EPSD	TCGA;ICGC	13.807	Loss
Other_PLK_PLK2_PLK2_ST	Q969H0	FBXW7	Q9NYY3	PLK2	S10	V8L	8	Missense	proximal	-2	no	13.508	14.431	EPSD	TCGA;ICGC;COSMIC	13.807	Gain
Other_PLK_PLK2_PLK2_ST	Q969H0	FBXW7	Q9NYY3	PLK2	S176	E177Q	177	Missense	proximal	1	no	20.125	16.036	PhosphoSitePlus;EPSD	TCGA;ICGC;COSMIC	13.807	Down-regulation
Other_PLK_PLK2_PLK2_ST	Q969H0	FBXW7	Q9NYY3	PLK2	S176	E177K	177	Missense	proximal	1	no	20.125	20.580	PhosphoSitePlus;EPSD	TCGA;ICGC;COSMIC	13.807	Up-regulation
Other_PLK_PLK2_PLK2_ST	Q969H0	FBXW7	Q9NYY3	PLK2	S176	R179C	179	Missense	distal	3	no	20.125	22.215	PhosphoSitePlus;EPSD	TCGA;ICGC;COSMIC	13.807	Up-regulation
Other_PLK_PLK2_PLK2_ST	Q969H0	FBXW7	Q9NYY3	PLK2	S176	R179H	179	Missense	distal	3	no	20.125	19.034	PhosphoSitePlus;EPSD	TCGA;ICGC;COSMIC	13.807	Down-regulation
Other_PLK_PLK2_PLK2_ST	Q16143	SNCB	Q9NYY3	PLK2	S118	E125K	125	Missense	distal	7	no	13.950	13.657	PhosphoSitePlus	TCGA;ICGC;COSMIC	13.807	Loss
Other_PLK_PLK2_PLK2_ST	Q16143	SNCB	Q9NYY3	PLK2	S118	M112V	112	Missense	distal	-6	no	13.950	12.577	PhosphoSitePlus	TCGA;ICGC;COSMIC	13.807	Loss
Other_PLK_PLK2_PLK2_ST	Q16143	SNCB	Q9NYY3	PLK2	S118	L111P	111	Missense	distal	-7	no	13.950	13.060	PhosphoSitePlus	TCGA;ICGC	13.807	Loss
Other_PLK_PLK2_PLK2_ST	Q16143	SNCB	Q9NYY3	PLK2	S118	E120D	120	Missense	proximal	2	no	13.950	14.004	PhosphoSitePlus	TCGA;ICGC	13.807	Up-regulation
Other_PLK_PLK2_PLK2_ST	Q16143	SNCB	Q9NYY3	PLK2	S118	E125G	125	Missense	distal	7	no	13.950	13.952	PhosphoSitePlus	TCGA;ICGC	13.807	Up-regulation
Other_PLK_PLK2_PLK2_ST	P53350	PLK1	Q9NYY3	PLK2	S137	R134H	134	Missense	distal	-3	no	23.568	24.758	PhosphoSitePlus	TCGA;ICGC	13.807	Up-regulation
Other_PLK_PLK2_PLK2_ST	P53350	PLK1	Q9NYY3	PLK2	T366	V369A	369	Missense	distal	3	no	17.311	16.187	EPSD	TCGA;ICGC;COSMIC	13.807	Down-regulation
Other_PLK_PLK2_PLK2_ST	P53350	PLK1	Q9NYY3	PLK2	S450	R456C	456	Missense	distal	6	no	14.368	17.263	EPSD	TCGA;ICGC;COSMIC	13.807	Up-regulation
Other_PLK_PLK2_PLK2_ST	P53350	PLK1	Q9NYY3	PLK2	S450	D457G	457	Missense	distal	7	no	14.368	14.309	EPSD	TCGA;ICGC;COSMIC	13.807	Down-regulation
Other_PLK_PLK2_PLK2_ST	P53350	PLK1	Q9NYY3	PLK2	S450	R456H	456	Missense	distal	6	no	14.368	15.924	EPSD	TCGA;ICGC;COSMIC	13.807	Up-regulation
Other_PLK_PLK2_PLK2_ST	P53350	PLK1	Q9NYY3	PLK2	T498	E501K	501	Missense	distal	3	no	11.776	13.915	EPSD	TCGA;ICGC;COSMIC	13.807	Gain
Other_PLK_PLK2_PLK2_ST	P53350	PLK1	Q9NYY3	PLK2	S578	R579Q	579	Missense	proximal	1	no	14.998	13.172	EPSD	TCGA;ICGC;COSMIC	13.807	Loss
Other_PLK_PLK2_PLK2_ST	P53350	PLK1	Q9NYY3	PLK2	S578	Y582C	582	Missense	distal	4	no	14.998	11.782	EPSD	TCGA;ICGC;COSMIC	13.807	Loss
Other_PLK_PLK2_PLK2_ST	P53350	PLK1	Q9NYY3	PLK2	S578	E575K	575	Missense	distal	-3	no	14.998	13.658	EPSD	TCGA;ICGC;COSMIC	13.807	Loss
Other_PLK_PLK2_PLK2_ST	P53350	PLK1	Q9NYY3	PLK2	S578	L580F	580	Missense	proximal	2	no	14.998	15.001	EPSD	TCGA;ICGC;COSMIC	13.807	Up-regulation
Other_PLK_PLK2_PLK2_ST	P53350	PLK1	Q9NYY3	PLK2	S578	A583T	583	Missense	distal	5	no	14.998	15.215	EPSD	TCGA;ICGC;COSMIC;CCLE	13.807	Up-regulation
Other_PLK_PLK2_PLK2_ST	P37840	SNCA	Q9NYY3	PLK2	S129	D135Y	135	Missense	distal	6	no	17.753	17.321	PhosphoSitePlus	TCGA;ICGC;COSMIC	13.807	Down-regulation
Other_PLK_PLK2_PLK2_ST	P37840	SNCA	Q9NYY3	PLK2	S129	S129F	129	Missense	central	0	yes	17.753	0.000	PhosphoSitePlus	TCGA;ICGC;COSMIC	13.807	Loss
TKL_RAF_RAF_ARAF_ST	Q92934	BAD	P10398	ARAF	S75	S71I	71	Missense	distal	-4	no	6.566	6.391	PhosphoSitePlus;EPSD	TCGA;ICGC;COSMIC	2.916	Down-regulation
TKL_RAF_RAF_ARAF_ST	Q92934	BAD	P10398	ARAF	S99	A100T	100	Missense	proximal	1	no	6.419	6.368	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	2.916	Down-regulation
TKL_RAF_RAF_ARAF_ST	Q92934	BAD	P10398	ARAF	S118	M117I	117	Missense	proximal	-1	no	6.098	6.187	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	2.916	Up-regulation
TKL_RAF_RAF_ARAF_ST	Q15599	SLC9A3R2	P10398	ARAF	S261	V256I	256	Missense	distal	-5	no	3.333	3.376	EPSD	TCGA;ICGC;COSMIC	2.916	Up-regulation
TKL_RAF_RAF_ARAF_ST	Q02750	MAP2K1	P10398	ARAF	S218	V224M	224	Missense	distal	6	no	6.728	6.740	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	2.916	Up-regulation
TKL_RAF_RAF_ARAF_ST	Q02750	MAP2K1	P10398	ARAF	S222	V224M	224	Missense	proximal	2	no	6.846	6.839	PhosphoSitePlus;EPSD	TCGA;ICGC;COSMIC	2.916	Down-regulation
TKL_RAF_RAF_ARAF_ST	Q02750	MAP2K1	P10398	ARAF	S222	R227K	227	Missense	distal	5	no	6.846	7.095	PhosphoSitePlus;EPSD	TCGA;ICGC;COSMIC	2.916	Up-regulation
CMGC_DYRK_DYRK1_DYRK1B_ST	Q02363	ID2	Q9Y463	DYRK1B	S16	N13S	13	Missense	distal	-3	no	0.053	0.062	EPSD	TCGA;ICGC;COSMIC	0.062	Gain
CMGC_DYRK_DYRK1_DYRK1B_ST	Q9Y463	DYRK1B	Q9Y463	DYRK1B	T41	A43T	43	Missense	proximal	2	no	0.066	0.067	EPSD	TCGA;ICGC;COSMIC	0.062	Up-regulation
CMGC_DYRK_DYRK1_DYRK1B_ST	Q9Y463	DYRK1B	Q9Y463	DYRK1B	T41	R46H	46	Missense	distal	5	no	0.066	0.071	EPSD	TCGA;ICGC;COSMIC	0.062	Up-regulation
CMGC_DYRK_DYRK1_DYRK1B_ST	Q9Y463	DYRK1B	Q9Y463	DYRK1B	S49	A43T	43	Missense	distal	-6	no	0.082	0.081	EPSD	TCGA;ICGC;COSMIC	0.062	Down-regulation
CMGC_DYRK_DYRK1_DYRK1B_ST	Q9Y463	DYRK1B	Q9Y463	DYRK1B	S49	R46H	46	Missense	distal	-3	no	0.082	0.051	EPSD	TCGA;ICGC;COSMIC	0.062	Loss
CMGC_DYRK_DYRK1_DYRK1B_ST	Q9Y463	DYRK1B	Q9Y463	DYRK1B	S554	L549F	549	Missense	distal	-5	no	0.101	0.099	EPSD	TCGA;COSMIC	0.062	Down-regulation
CMGC_DYRK_DYRK1_DYRK1B_ST	P24385	CCND1	Q9Y463	DYRK1B	S131	E135D	135	Missense	distal	4	no	0.088	0.089	EPSD	TCGA;ICGC;COSMIC	0.062	Up-regulation
CMGC_DYRK_DYRK1_DYRK1B_ST	P24385	CCND1	Q9Y463	DYRK1B	S257	R260C	260	Missense	distal	3	no	0.070	0.069	EPSD	TCGA;ICGC;COSMIC	0.062	Down-regulation
CMGC_DYRK_DYRK1_DYRK1B_ST	P24385	CCND1	Q9Y463	DYRK1B	S257	S258G	258	Missense	proximal	1	no	0.070	0.057	EPSD	TCGA;ICGC;COSMIC	0.062	Loss
CMGC_DYRK_DYRK1_DYRK1B_ST	P24385	CCND1	Q9Y463	DYRK1B	S257	R260H	260	Missense	distal	3	no	0.070	0.073	EPSD	TCGA;ICGC;COSMIC;GDSC;CCLE	0.062	Up-regulation
CMGC_DYRK_DYRK1_DYRK1B_ST	P24385	CCND1	Q9Y463	DYRK1B	T286	P287R	287	Missense	proximal	1	no	0.074	0.021	EPSD	TCGA;ICGC;COSMIC;GDSC;CCLE	0.062	Loss
CMGC_DYRK_DYRK1_DYRK1B_ST	P24385	CCND1	Q9Y463	DYRK1B	T286	P287T	287	Missense	proximal	1	no	0.074	0.031	EPSD	TCGA;ICGC;COSMIC;CCLE	0.062	Loss
CMGC_DYRK_DYRK1_DYRK1B_ST	P24385	CCND1	Q9Y463	DYRK1B	T286	P287L	287	Missense	proximal	1	no	0.074	0.007	EPSD	TCGA;ICGC;COSMIC;GDSC;CCLE	0.062	Loss
CMGC_DYRK_DYRK1_DYRK1B_ST	P24385	CCND1	Q9Y463	DYRK1B	T286	D282H	282	Missense	distal	-4	no	0.074	0.073	EPSD	TCGA;ICGC;COSMIC	0.062	Down-regulation
CMGC_DYRK_DYRK1_DYRK1B_ST	P24385	CCND1	Q9Y463	DYRK1B	T286	P287H	287	Missense	proximal	1	no	0.074	0.026	EPSD	TCGA;ICGC;COSMIC	0.062	Loss
CMGC_DYRK_DYRK1_DYRK1B_ST	P24385	CCND1	Q9Y463	DYRK1B	T286	T286R	286	Missense	central	0	yes	0.074	0.000	EPSD	TCGA;ICGC;COSMIC	0.062	Loss
CMGC_DYRK_DYRK1_DYRK1B_ST	P24385	CCND1	Q9Y463	DYRK1B	T286	V293G	293	Missense	distal	7	no	0.074	0.073	EPSD	TCGA;ICGC;COSMIC;CCLE	0.062	Down-regulation
CMGC_DYRK_DYRK1_DYRK1B_ST	P24385	CCND1	Q9Y463	DYRK1B	T286	T286I	286	Missense	central	0	yes	0.074	0.000	EPSD	TCGA;ICGC;COSMIC	0.062	Loss
CMGC_DYRK_DYRK1_DYRK1B_ST	P24385	CCND1	Q9Y463	DYRK1B	T286	P287S	287	Missense	proximal	1	no	0.074	0.033	EPSD	TCGA;ICGC;COSMIC	0.062	Loss
CMGC_DYRK_DYRK1_DYRK1B_ST	P24385	CCND1	Q9Y463	DYRK1B	T286	T286A	286	Missense	central	0	yes	0.074	0.000	EPSD	TCGA;ICGC;COSMIC	0.062	Loss
CMGC_DYRK_DYRK1_DYRK1B_ST	P24385	CCND1	Q9Y463	DYRK1B	T288	P287L	287	Missense	proximal	-1	no	0.077	0.081	PhosphoSitePlus	TCGA;ICGC;COSMIC;GDSC;CCLE	0.062	Up-regulation
CMGC_DYRK_DYRK1_DYRK1B_ST	P24385	CCND1	Q9Y463	DYRK1B	T288	D282H	282	Missense	distal	-6	no	0.077	0.076	PhosphoSitePlus	TCGA;ICGC;COSMIC	0.062	Down-regulation
CMGC_DYRK_DYRK1_DYRK1B_ST	P24385	CCND1	Q9Y463	DYRK1B	T288	P287H	287	Missense	proximal	-1	no	0.077	0.080	PhosphoSitePlus	TCGA;ICGC;COSMIC	0.062	Up-regulation
CMGC_DYRK_DYRK1_DYRK1B_ST	P24385	CCND1	Q9Y463	DYRK1B	T288	T286R	286	Missense	proximal	-2	no	0.077	0.082	PhosphoSitePlus	TCGA;ICGC;COSMIC	0.062	Up-regulation
CMGC_DYRK_DYRK1_DYRK1B_ST	P24385	CCND1	Q9Y463	DYRK1B	T288	V293G	293	Missense	distal	5	no	0.077	0.083	PhosphoSitePlus	TCGA;ICGC;COSMIC;CCLE	0.062	Up-regulation
CMGC_DYRK_DYRK1_DYRK1B_ST	P24385	CCND1	Q9Y463	DYRK1B	T288	T286I	286	Missense	proximal	-2	no	0.077	0.072	PhosphoSitePlus	TCGA;ICGC;COSMIC	0.062	Down-regulation
CMGC_DYRK_DYRK1_DYRK1B_ST	P24385	CCND1	Q9Y463	DYRK1B	T288	P287S	287	Missense	proximal	-1	no	0.077	0.078	PhosphoSitePlus	TCGA;ICGC;COSMIC	0.062	Up-regulation
CMGC_DYRK_DYRK1_DYRK1B_ST	P24385	CCND1	Q9Y463	DYRK1B	T288	V281E	281	Missense	distal	-7	no	0.077	0.076	PhosphoSitePlus	TCGA;ICGC;COSMIC	0.062	Down-regulation
CMGC_DYRK_DYRK1_DYRK1B_ST	P24385	CCND1	Q9Y463	DYRK1B	T288	T286A	286	Missense	proximal	-2	no	0.077	0.075	PhosphoSitePlus	TCGA;ICGC;COSMIC	0.062	Down-regulation
CMGC_DYRK_DYRK1_DYRK1B_ST	P38936	CDKN1A	Q9Y463	DYRK1B	T57	E56K	56	Missense	proximal	-1	no	0.101	0.099	EPSD	TCGA;ICGC;COSMIC	0.062	Down-regulation
CMGC_DYRK_DYRK1_DYRK1B_ST	P38936	CDKN1A	Q9Y463	DYRK1B	T57	P58L	58	Missense	proximal	1	no	0.101	0.034	EPSD	TCGA;ICGC;COSMIC	0.062	Loss
CMGC_DYRK_DYRK1_DYRK1B_ST	P38936	CDKN1A	Q9Y463	DYRK1B	T97	R94W	94	Missense	distal	-3	no	0.106	0.073	EPSD	TCGA;ICGC;COSMIC	0.062	Down-regulation
CMGC_DYRK_DYRK1_DYRK1B_ST	P38936	CDKN1A	Q9Y463	DYRK1B	T97	R93S	93	Missense	distal	-4	no	0.106	0.108	EPSD	TCGA;ICGC;COSMIC	0.062	Up-regulation
CMGC_DYRK_DYRK1_DYRK1B_ST	P38936	CDKN1A	Q9Y463	DYRK1B	T97	R94P	94	Missense	distal	-3	no	0.106	0.061	EPSD	TCGA;ICGC;COSMIC	0.062	Loss
CMGC_DYRK_DYRK1_DYRK1B_ST	P38936	CDKN1A	Q9Y463	DYRK1B	T97	P95S	95	Missense	proximal	-2	no	0.106	0.107	EPSD	TCGA;ICGC;COSMIC	0.062	Up-regulation
CMGC_DYRK_DYRK1_DYRK1B_ST	P38936	CDKN1A	Q9Y463	DYRK1B	S98	P95S	95	Missense	distal	-3	no	0.043	0.068	EPSD	TCGA;ICGC;COSMIC	0.062	Gain
CMGC_DYRK_DYRK1_DYRK1B_ST	P38936	CDKN1A	Q9Y463	DYRK1B	S130	D136H	136	Missense	distal	6	no	0.073	0.072	EPSD	TCGA;ICGC;COSMIC	0.062	Down-regulation
CMGC_DYRK_DYRK1_DYRK1B_ST	P38936	CDKN1A	Q9Y463	DYRK1B	S130	G132C	132	Missense	proximal	2	no	0.073	0.076	EPSD	TCGA;ICGC;COSMIC	0.062	Up-regulation
CMGC_DYRK_DYRK1_DYRK1B_ST	P38936	CDKN1A	Q9Y463	DYRK1B	S130	E128K	128	Missense	proximal	-2	no	0.073	0.080	EPSD	TCGA;ICGC;COSMIC	0.062	Up-regulation
CMGC_DYRK_DYRK1_DYRK1B_ST	P38936	CDKN1A	Q9Y463	DYRK1B	S130	G135A	135	Missense	distal	5	no	0.073	0.069	EPSD	TCGA	0.062	Down-regulation
CMGC_DYRK_DYRK1_DYRK1B_ST	P20823	HNF1A	Q9Y463	DYRK1B	T74	D75N	75	Missense	proximal	1	no	0.066	0.047	EPSD	TCGA;ICGC;COSMIC	0.062	Loss
CMGC_DYRK_DYRK1_DYRK1B_ST	P20823	HNF1A	Q9Y463	DYRK1B	T74	E79K	79	Missense	distal	5	no	0.066	0.057	EPSD	TCGA;ICGC;COSMIC	0.062	Loss
CMGC_DYRK_DYRK1_DYRK1B_ST	P20823	HNF1A	Q9Y463	DYRK1B	T74	D76N	76	Missense	proximal	2	no	0.066	0.067	EPSD	TCGA;ICGC;COSMIC	0.062	Up-regulation
CMGC_DYRK_DYRK1_DYRK1B_ST	P20823	HNF1A	Q9Y463	DYRK1B	T82	T82K	82	Missense	central	0	yes	0.107	0.000	EPSD	TCGA;ICGC;COSMIC	0.062	Loss
CMGC_DYRK_DYRK1_DYRK1B_ST	P20823	HNF1A	Q9Y463	DYRK1B	T82	D75N	75	Missense	distal	-7	no	0.107	0.108	EPSD	TCGA;ICGC;COSMIC	0.062	Up-regulation
CMGC_DYRK_DYRK1_DYRK1B_ST	P20823	HNF1A	Q9Y463	DYRK1B	T82	E79K	79	Missense	distal	-3	no	0.107	0.125	EPSD	TCGA;ICGC;COSMIC	0.062	Up-regulation
CMGC_DYRK_DYRK1_DYRK1B_ST	P20823	HNF1A	Q9Y463	DYRK1B	T82	D80G	80	Missense	proximal	-2	no	0.107	0.106	EPSD	TCGA;ICGC;COSMIC	0.062	Down-regulation
CMGC_DYRK_DYRK1_DYRK1B_ST	P20823	HNF1A	Q9Y463	DYRK1B	T82	D76N	76	Missense	distal	-6	no	0.107	0.106	EPSD	TCGA;ICGC;COSMIC	0.062	Down-regulation
CMGC_DYRK_DYRK1_DYRK1B_ST	P20823	HNF1A	Q9Y463	DYRK1B	S93	P94H	94	Missense	proximal	1	no	0.078	0.030	EPSD	TCGA;ICGC;COSMIC	0.062	Loss
CMGC_DYRK_DYRK1_DYRK1B_ST	P20823	HNF1A	Q9Y463	DYRK1B	S93	E96K	96	Missense	distal	3	no	0.078	0.074	EPSD	TCGA;ICGC;COSMIC	0.062	Down-regulation
CMGC_DYRK_DYRK1_DYRK1B_ST	P20823	HNF1A	Q9Y463	DYRK1B	S247	L254Q	254	Missense	distal	7	no	0.144	0.145	EPSD	TCGA;ICGC;COSMIC	0.062	Up-regulation
CMGC_DYRK_DYRK1_DYRK1B_ST	P20823	HNF1A	Q9Y463	DYRK1B	S247	R244G	244	Missense	distal	-3	no	0.144	0.107	EPSD	TCGA;ICGC;COSMIC	0.062	Down-regulation
CMGC_DYRK_DYRK1_DYRK1B_ST	P20823	HNF1A	Q9Y463	DYRK1B	S249	L254Q	254	Missense	distal	5	no	0.096	0.090	PhosphoSitePlus	TCGA;ICGC;COSMIC	0.062	Down-regulation
CMGC_DYRK_DYRK1_DYRK1B_ST	P20823	HNF1A	Q9Y463	DYRK1B	S249	R244G	244	Missense	distal	-5	no	0.096	0.091	PhosphoSitePlus	TCGA;ICGC;COSMIC	0.062	Down-regulation
CMGC_DYRK_DYRK1_DYRK1B_ST	O75533	SF3B1	Q9Y463	DYRK1B	S129	R124L	124	Missense	distal	-5	no	0.090	0.086	EPSD	TCGA;ICGC;COSMIC	0.062	Down-regulation
CMGC_DYRK_DYRK1_DYRK1B_ST	O75533	SF3B1	Q9Y463	DYRK1B	S129	R124Q	124	Missense	distal	-5	no	0.090	0.086	EPSD	TCGA;ICGC;COSMIC	0.062	Down-regulation
CMGC_DYRK_DYRK1_DYRK1B_ST	O75533	SF3B1	Q9Y463	DYRK1B	T142	P135S	135	Missense	distal	-7	no	0.060	0.062	EPSD	TCGA;ICGC;COSMIC	0.062	Gain
CMGC_DYRK_DYRK1_DYRK1B_ST	O75533	SF3B1	Q9Y463	DYRK1B	T142	G139E	139	Missense	distal	-3	no	0.060	0.069	EPSD	TCGA;ICGC	0.062	Gain
CMGC_DYRK_DYRK1_DYRK1B_ST	O75533	SF3B1	Q9Y463	DYRK1B	T207	Q206E	206	Missense	proximal	-1	no	0.086	0.088	EPSD	TCGA;ICGC;COSMIC	0.062	Up-regulation
CMGC_DYRK_DYRK1_DYRK1B_ST	O75533	SF3B1	Q9Y463	DYRK1B	T223	P228S	228	Missense	distal	5	no	0.074	0.071	EPSD	TCGA;ICGC;COSMIC	0.062	Down-regulation
CMGC_DYRK_DYRK1_DYRK1B_ST	O75533	SF3B1	Q9Y463	DYRK1B	T223	Q220K	220	Missense	distal	-3	no	0.074	0.089	EPSD	TCGA;ICGC;COSMIC	0.062	Up-regulation
CMGC_DYRK_DYRK1_DYRK1B_ST	O75533	SF3B1	Q9Y463	DYRK1B	T261	D255N	255	Missense	distal	-6	no	0.077	0.076	EPSD	TCGA;ICGC;COSMIC	0.062	Down-regulation
CMGC_DYRK_DYRK1_DYRK1B_ST	O75533	SF3B1	Q9Y463	DYRK1B	T261	P258L	258	Missense	distal	-3	no	0.077	0.096	EPSD	TCGA	0.062	Up-regulation
CMGC_DYRK_DYRK1_DYRK1B_ST	O75533	SF3B1	Q9Y463	DYRK1B	T273	P274L	274	Missense	proximal	1	no	0.063	-0.004	EPSD	TCGA;ICGC;COSMIC	0.062	Loss
CMGC_DYRK_DYRK1_DYRK1B_ST	O75533	SF3B1	Q9Y463	DYRK1B	T303	S308R	308	Missense	distal	5	no	0.063	0.062	EPSD	TCGA;ICGC;COSMIC	0.062	Down-regulation
CMGC_DYRK_DYRK1_DYRK1B_ST	O75533	SF3B1	Q9Y463	DYRK1B	S344	P351L	351	Missense	distal	7	no	0.071	0.069	EPSD	TCGA;ICGC;COSMIC	0.062	Down-regulation
CMGC_DYRK_DYRK1_DYRK1B_ST	O75533	SF3B1	Q9Y463	DYRK1B	S344	P351S	351	Missense	distal	7	no	0.071	0.070	EPSD	TCGA;ICGC;COSMIC	0.062	Down-regulation
CMGC_DYRK_DYRK1_DYRK1B_ST	O75533	SF3B1	Q9Y463	DYRK1B	T354	P351L	351	Missense	distal	-3	no	0.051	0.070	EPSD	TCGA;ICGC;COSMIC	0.062	Gain
CMGC_DYRK_DYRK1_DYRK1B_ST	O75533	SF3B1	Q9Y463	DYRK1B	T354	P351S	351	Missense	distal	-3	no	0.051	0.075	EPSD	TCGA;ICGC;COSMIC	0.062	Gain
CMGC_DYRK_DYRK1_DYRK1B_ST	O75533	SF3B1	Q9Y463	DYRK1B	T369	P370L	370	Missense	proximal	1	no	0.065	-0.001	EPSD	TCGA;ICGC;COSMIC	0.062	Loss
CMGC_DYRK_DYRK1_DYRK1B_ST	O75533	SF3B1	Q9Y463	DYRK1B	T369	A368D	368	Missense	proximal	-1	no	0.065	0.064	EPSD	TCGA;ICGC;COSMIC	0.062	Down-regulation
CMGC_DYRK_DYRK1_DYRK1B_ST	O75533	SF3B1	Q9Y463	DYRK1B	T369	A368T	368	Missense	proximal	-1	no	0.065	0.064	EPSD	TCGA;ICGC;COSMIC	0.062	Down-regulation
CMGC_DYRK_DYRK1_DYRK1B_ST	O75533	SF3B1	Q9Y463	DYRK1B	T371	P370L	370	Missense	proximal	-1	no	0.059	0.063	EPSD	TCGA;ICGC;COSMIC	0.062	Gain
CMGC_DYRK_DYRK1_DYRK1B_ST	O75533	SF3B1	Q9Y463	DYRK1B	S400	R397C	397	Missense	distal	-3	no	0.088	0.072	EPSD	TCGA;ICGC;COSMIC	0.062	Down-regulation
CMGC_DYRK_DYRK1_DYRK1B_ST	O75533	SF3B1	Q9Y463	DYRK1B	T434	A433G	433	Missense	proximal	-1	no	0.109	0.110	PhosphoSitePlus	TCGA;ICGC;COSMIC	0.062	Up-regulation
CMGC_DYRK_DYRK1_DYRK1B_ST	O75533	SF3B1	Q9Y463	DYRK1B	S488	E490K	490	Missense	proximal	2	no	0.064	0.066	EPSD	TCGA;ICGC;COSMIC	0.062	Up-regulation
CMGC_DYRK_DYRK1_DYRK1B_ST	O75533	SF3B1	Q9Y463	DYRK1B	T508	L502F	502	Missense	distal	-6	no	0.103	0.105	EPSD	TCGA;ICGC;COSMIC	0.062	Up-regulation
CMGC_DYRK_DYRK1_DYRK1B_ST	O75533	SF3B1	Q9Y463	DYRK1B	S541	S541P	541	Missense	central	0	yes	0.071	0.000	EPSD	TCGA;ICGC;COSMIC	0.062	Loss
CMGC_DYRK_DYRK1_DYRK1B_ST	O75533	SF3B1	Q9Y463	DYRK1B	S541	L544P	544	Missense	distal	3	no	0.071	0.067	EPSD	TCGA;ICGC;COSMIC	0.062	Down-regulation
CMGC_DYRK_DYRK1_DYRK1B_ST	O75533	SF3B1	Q9Y463	DYRK1B	T1170	D1175Y	1175	Missense	distal	5	no	0.073	0.072	EPSD	TCGA;ICGC;COSMIC	0.062	Down-regulation
CMGC_DYRK_DYRK1_DYRK1B_ST	O75533	SF3B1	Q9Y463	DYRK1B	T1170	V1169I	1169	Missense	proximal	-1	no	0.073	0.075	EPSD	TCGA;ICGC;COSMIC	0.062	Up-regulation
CAMK_MAPKAPK_MNK_MKNK2_ST	P23246	SFPQ	Q9HBH9	MKNK2	S8	S2F	2	Missense	distal	-6	no	26.618	26.609	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	18.660	Down-regulation
CAMK_MAPKAPK_MNK_MKNK2_ST	P23246	SFPQ	Q9HBH9	MKNK2	S283	R287K	287	Missense	distal	4	no	32.280	32.203	PhosphoSitePlus;EPSD	TCGA	18.660	Down-regulation
CAMK_MAPKAPK_MNK_MKNK2_ST	P23246	SFPQ	Q9HBH9	MKNK2	S283	S283C	283	Missense	central	0	yes	32.280	0.000	PhosphoSitePlus;EPSD	TCGA;ICGC;COSMIC	18.660	Loss
CAMK_MAPKAPK_MNK_MKNK2_ST	P23246	SFPQ	Q9HBH9	MKNK2	S283	E290K	290	Missense	distal	7	no	32.280	32.656	PhosphoSitePlus;EPSD	TCGA;ICGC;COSMIC	18.660	Up-regulation
CAMK_MAPKAPK_MNK_MKNK2_ST	P23246	SFPQ	Q9HBH9	MKNK2	S379	N384S	384	Missense	distal	5	no	20.561	20.941	EPSD	TCGA;ICGC;COSMIC	18.660	Up-regulation
CAMK_MAPKAPK_MNK_MKNK2_ST	P23246	SFPQ	Q9HBH9	MKNK2	S379	E385K	385	Missense	distal	6	no	20.561	22.566	EPSD	TCGA;ICGC;COSMIC	18.660	Up-regulation
CAMK_MAPKAPK_MNK_MKNK2_ST	O43597	SPRY2	Q9HBH9	MKNK2	S97	L94R	94	Missense	distal	-3	no	18.667	20.905	EPSD	TCGA;ICGC;COSMIC	18.660	Up-regulation
CAMK_MAPKAPK_MNK_MKNK2_ST	O43597	SPRY2	Q9HBH9	MKNK2	S97	H96R	96	Missense	proximal	-1	no	18.667	18.840	EPSD	TCGA;ICGC	18.660	Up-regulation
CAMK_MAPKAPK_MNK_MKNK2_ST	O43597	SPRY2	Q9HBH9	MKNK2	S112	A105V	105	Missense	distal	-7	no	31.862	32.620	PhosphoSitePlus;EPSD	TCGA;ICGC;COSMIC	18.660	Up-regulation
CAMK_MAPKAPK_MNK_MKNK2_ST	O43597	SPRY2	Q9HBH9	MKNK2	S112	R119L	119	Missense	distal	7	no	31.862	31.481	PhosphoSitePlus;EPSD	TCGA;ICGC;COSMIC	18.660	Down-regulation
CAMK_MAPKAPK_MNK_MKNK2_ST	O43597	SPRY2	Q9HBH9	MKNK2	S120	S127G	127	Missense	distal	7	no	21.544	21.539	EPSD	TCGA;ICGC;COSMIC	18.660	Down-regulation
CAMK_MAPKAPK_MNK_MKNK2_ST	O43597	SPRY2	Q9HBH9	MKNK2	S120	R119L	119	Missense	proximal	-1	no	21.544	21.268	EPSD	TCGA;ICGC;COSMIC	18.660	Down-regulation
CAMK_MAPKAPK_MNK_MKNK2_ST	O43597	SPRY2	Q9HBH9	MKNK2	S121	S127G	127	Missense	distal	6	no	31.478	31.929	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	18.660	Up-regulation
CAMK_MAPKAPK_MNK_MKNK2_ST	O43597	SPRY2	Q9HBH9	MKNK2	S121	R119L	119	Missense	proximal	-2	no	31.478	28.064	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	18.660	Down-regulation
CAMK_MAPKAPK_MNK_MKNK2_ST	O43597	SPRY2	Q9HBH9	MKNK2	T122	S127G	127	Missense	distal	5	no	21.489	23.237	EPSD	TCGA;ICGC;COSMIC	18.660	Up-regulation
CAMK_MAPKAPK_MNK_MKNK2_ST	O43597	SPRY2	Q9HBH9	MKNK2	T122	R119L	119	Missense	distal	-3	no	21.489	19.251	EPSD	TCGA;ICGC;COSMIC	18.660	Down-regulation
CAMK_MAPKAPK_MNK_MKNK2_ST	O43597	SPRY2	Q9HBH9	MKNK2	T124	S127G	127	Missense	distal	3	no	19.649	19.737	EPSD	TCGA;ICGC;COSMIC	18.660	Up-regulation
CAMK_MAPKAPK_MNK_MKNK2_ST	O43597	SPRY2	Q9HBH9	MKNK2	T124	R119L	119	Missense	distal	-5	no	19.649	19.487	EPSD	TCGA;ICGC;COSMIC	18.660	Down-regulation
CAMK_MAPKAPK_MNK_MKNK2_ST	O43597	SPRY2	Q9HBH9	MKNK2	S138	G137R	137	Missense	proximal	-1	no	18.707	18.733	EPSD	TCGA;ICGC;COSMIC	18.660	Up-regulation
CAMK_MAPKAPK_MNK_MKNK2_ST	O43597	SPRY2	Q9HBH9	MKNK2	S138	P144S	144	Missense	distal	6	no	18.707	19.929	EPSD	TCGA;ICGC;COSMIC	18.660	Up-regulation
CAMK_MAPKAPK_MNK_MKNK2_ST	O43597	SPRY2	Q9HBH9	MKNK2	S138	L135M	135	Missense	distal	-3	no	18.707	19.293	EPSD	TCGA;ICGC	18.660	Up-regulation
CAMK_MAPKAPK_MNK_MKNK2_ST	O43597	SPRY2	Q9HBH9	MKNK2	S138	S142F	142	Missense	distal	4	no	18.707	18.453	EPSD	TCGA;ICGC;COSMIC	18.660	Loss
CAMK_MAPKAPK_MNK_MKNK2_ST	O43597	SPRY2	Q9HBH9	MKNK2	S141	G137R	137	Missense	distal	-4	no	19.039	18.248	EPSD	TCGA;ICGC;COSMIC	18.660	Loss
CAMK_MAPKAPK_MNK_MKNK2_ST	O43597	SPRY2	Q9HBH9	MKNK2	S141	P144S	144	Missense	distal	3	no	19.039	19.077	EPSD	TCGA;ICGC;COSMIC	18.660	Up-regulation
CAMK_MAPKAPK_MNK_MKNK2_ST	O43597	SPRY2	Q9HBH9	MKNK2	S141	A146V	146	Missense	distal	5	no	19.039	17.889	EPSD	TCGA;ICGC;COSMIC	18.660	Loss
CAMK_MAPKAPK_MNK_MKNK2_ST	O43597	SPRY2	Q9HBH9	MKNK2	S141	L135M	135	Missense	distal	-6	no	19.039	19.050	EPSD	TCGA;ICGC	18.660	Up-regulation
CAMK_MAPKAPK_MNK_MKNK2_ST	O43597	SPRY2	Q9HBH9	MKNK2	S141	S142F	142	Missense	proximal	1	no	19.039	18.414	EPSD	TCGA;ICGC;COSMIC	18.660	Loss
CAMK_MAPKAPK_MNK_MKNK2_ST	Q15149	PLEC	Q9HBH9	MKNK2	S714	R713Q	713	Missense	proximal	-1	no	22.482	22.414	EPSD	TCGA;COSMIC;GDSC	18.660	Down-regulation
CAMK_MAPKAPK_MNK_MKNK2_ST	Q15149	PLEC	Q9HBH9	MKNK2	S714	R711W	711	Missense	distal	-3	no	22.482	20.946	EPSD	TCGA;COSMIC	18.660	Down-regulation
CAMK_MAPKAPK_MNK_MKNK2_ST	Q15149	PLEC	Q9HBH9	MKNK2	S714	E716K	716	Missense	proximal	2	no	22.482	21.450	EPSD	TCGA;COSMIC	18.660	Down-regulation
CAMK_MAPKAPK_MNK_MKNK2_ST	Q15149	PLEC	Q9HBH9	MKNK2	S714	A712V	712	Missense	proximal	-2	no	22.482	19.194	EPSD	TCGA;COSMIC	18.660	Down-regulation
CAMK_MAPKAPK_MNK_MKNK2_ST	Q15149	PLEC	Q9HBH9	MKNK2	S720	R724Q	724	Missense	distal	4	no	18.985	18.713	EPSD	TCGA;COSMIC	18.660	Down-regulation
CAMK_MAPKAPK_MNK_MKNK2_ST	Q15149	PLEC	Q9HBH9	MKNK2	S720	R713Q	713	Missense	distal	-7	no	18.985	18.773	EPSD	TCGA;COSMIC;GDSC	18.660	Down-regulation
CAMK_MAPKAPK_MNK_MKNK2_ST	Q15149	PLEC	Q9HBH9	MKNK2	S720	E716K	716	Missense	distal	-4	no	18.985	20.024	EPSD	TCGA;COSMIC	18.660	Up-regulation
CAMK_MAPKAPK_MNK_MKNK2_ST	Q15149	PLEC	Q9HBH9	MKNK2	S984	S990F	990	Missense	distal	6	no	19.469	18.598	EPSD	TCGA;COSMIC	18.660	Loss
CAMK_MAPKAPK_MNK_MKNK2_ST	Q15149	PLEC	Q9HBH9	MKNK2	S2833	R2832L	2832	Missense	proximal	-1	no	20.446	20.170	EPSD	TCGA	18.660	Down-regulation
CAMK_MAPKAPK_MNK_MKNK2_ST	Q15149	PLEC	Q9HBH9	MKNK2	S2833	R2826C	2826	Missense	distal	-7	no	20.446	20.150	EPSD	TCGA;COSMIC;GDSC	18.660	Down-regulation
CAMK_MAPKAPK_MNK_MKNK2_ST	Q15149	PLEC	Q9HBH9	MKNK2	S2833	R2826H	2826	Missense	distal	-7	no	20.446	19.756	EPSD	TCGA;COSMIC;GDSC;CCLE	18.660	Down-regulation
CAMK_MAPKAPK_MNK_MKNK2_ST	Q15149	PLEC	Q9HBH9	MKNK2	S2833	A2836T	2836	Missense	distal	3	no	20.446	20.444	EPSD	TCGA;COSMIC;GDSC;CCLE	18.660	Down-regulation
CAMK_MAPKAPK_MNK_MKNK2_ST	Q15149	PLEC	Q9HBH9	MKNK2	S2833	R2832C	2832	Missense	proximal	-1	no	20.446	20.179	EPSD	TCGA;COSMIC	18.660	Down-regulation
CAMK_MAPKAPK_MNK_MKNK2_ST	Q15149	PLEC	Q9HBH9	MKNK2	S2984	D2985N	2985	Missense	proximal	1	no	18.270	18.844	EPSD	TCGA;COSMIC	18.660	Gain
CAMK_MAPKAPK_MNK_MKNK2_ST	Q15149	PLEC	Q9HBH9	MKNK2	S3309	D3314G	3314	Missense	distal	5	no	15.994	18.826	EPSD	TCGA	18.660	Gain
CAMK_MAPKAPK_MNK_MKNK2_ST	Q15149	PLEC	Q9HBH9	MKNK2	S3319	G3324R	3324	Missense	distal	5	no	21.037	18.516	EPSD	TCGA;COSMIC	18.660	Loss
CAMK_MAPKAPK_MNK_MKNK2_ST	Q15149	PLEC	Q9HBH9	MKNK2	S3319	D3314G	3314	Missense	distal	-5	no	21.037	21.267	EPSD	TCGA	18.660	Up-regulation
CAMK_MAPKAPK_MNK_MKNK2_ST	Q15149	PLEC	Q9HBH9	MKNK2	S3322	G3324R	3324	Missense	proximal	2	no	20.899	21.349	EPSD	TCGA;COSMIC	18.660	Up-regulation
CAMK_MAPKAPK_MNK_MKNK2_ST	Q15149	PLEC	Q9HBH9	MKNK2	T3988	P3986Q	3986	Missense	proximal	-2	no	20.047	21.979	EPSD	TCGA;COSMIC	18.660	Up-regulation
CAMK_MAPKAPK_MNK_MKNK2_ST	Q15149	PLEC	Q9HBH9	MKNK2	S4271	S4272Y	4272	Missense	proximal	1	no	20.075	15.238	EPSD	TCGA;COSMIC	18.660	Loss
CAMK_MAPKAPK_MNK_MKNK2_ST	Q15149	PLEC	Q9HBH9	MKNK2	S4271	R4276C	4276	Missense	distal	5	no	20.075	19.173	EPSD	TCGA;COSMIC	18.660	Down-regulation
CAMK_MAPKAPK_MNK_MKNK2_ST	Q15149	PLEC	Q9HBH9	MKNK2	S4271	V4273M	4273	Missense	proximal	2	no	20.075	19.189	EPSD	TCGA;COSMIC;CCLE	18.660	Down-regulation
CAMK_MAPKAPK_MNK_MKNK2_ST	Q15149	PLEC	Q9HBH9	MKNK2	S4271	S4268A	4268	Missense	distal	-3	no	20.075	19.222	EPSD	TCGA;COSMIC	18.660	Down-regulation
CAMK_MAPKAPK_MNK_MKNK2_ST	Q15149	PLEC	Q9HBH9	MKNK2	S4382	R4381H	4381	Missense	proximal	-1	no	19.158	18.985	EPSD	TCGA;COSMIC;GDSC;CCLE	18.660	Down-regulation
CAMK_MAPKAPK_MNK_MKNK2_ST	Q15149	PLEC	Q9HBH9	MKNK2	S4382	S4389F	4389	Missense	distal	7	no	19.158	19.017	EPSD	TCGA;COSMIC	18.660	Down-regulation
CAMK_MAPKAPK_MNK_MKNK2_ST	Q15149	PLEC	Q9HBH9	MKNK2	S4384	R4381H	4381	Missense	distal	-3	no	21.702	20.200	EPSD	TCGA;COSMIC;GDSC;CCLE	18.660	Down-regulation
CAMK_MAPKAPK_MNK_MKNK2_ST	Q15149	PLEC	Q9HBH9	MKNK2	S4384	S4389F	4389	Missense	distal	5	no	21.702	21.142	EPSD	TCGA;COSMIC	18.660	Down-regulation
CAMK_MAPKAPK_MNK_MKNK2_ST	Q15149	PLEC	Q9HBH9	MKNK2	S4384	S4391F	4391	Missense	distal	7	no	21.702	21.561	EPSD	TCGA;COSMIC	18.660	Down-regulation
CAMK_MAPKAPK_MNK_MKNK2_ST	Q15149	PLEC	Q9HBH9	MKNK2	S4386	R4381H	4381	Missense	distal	-5	no	20.257	20.256	EPSD	TCGA;COSMIC;GDSC;CCLE	18.660	Down-regulation
CAMK_MAPKAPK_MNK_MKNK2_ST	Q15149	PLEC	Q9HBH9	MKNK2	S4386	S4389F	4389	Missense	distal	3	no	20.257	20.228	EPSD	TCGA;COSMIC	18.660	Down-regulation
CAMK_MAPKAPK_MNK_MKNK2_ST	Q15149	PLEC	Q9HBH9	MKNK2	S4386	S4391F	4391	Missense	distal	5	no	20.257	19.697	EPSD	TCGA;COSMIC	18.660	Down-regulation
CAMK_MAPKAPK_MNK_MKNK2_ST	Q15149	PLEC	Q9HBH9	MKNK2	S4400	R4401S	4401	Missense	proximal	1	no	17.499	18.673	EPSD	TCGA;COSMIC	18.660	Gain
CAMK_MAPKAPK_MNK_MKNK2_ST	Q15149	PLEC	Q9HBH9	MKNK2	S4462	D4460N	4460	Missense	proximal	-2	no	17.392	19.006	EPSD	TCGA;COSMIC;GDSC;CCLE	18.660	Gain
CAMK_MAPKAPK_MNK_MKNK2_ST	Q15149	PLEC	Q9HBH9	MKNK2	S4616	G4621C	4621	Missense	distal	5	no	21.918	18.495	EPSD	TCGA;COSMIC	18.660	Loss
CAMK_MAPKAPK_MNK_MKNK2_ST	Q15149	PLEC	Q9HBH9	MKNK2	S4616	S4620F	4620	Missense	distal	4	no	21.918	21.664	EPSD	TCGA;COSMIC	18.660	Down-regulation
CAMK_MAPKAPK_MNK_MKNK2_ST	Q15149	PLEC	Q9HBH9	MKNK2	T4628	G4621C	4621	Missense	distal	-7	no	19.482	20.241	EPSD	TCGA;COSMIC	18.660	Up-regulation
CAMK_MAPKAPK_MNK_MKNK2_ST	Q15149	PLEC	Q9HBH9	MKNK2	T4628	T4632I	4632	Missense	distal	4	no	19.482	19.302	EPSD	TCGA;COSMIC	18.660	Down-regulation
CAMK_MAPKAPK_MNK_MKNK2_ST	Q15149	PLEC	Q9HBH9	MKNK2	S4630	A4636V	4636	Missense	distal	6	no	18.991	17.132	EPSD	TCGA;COSMIC	18.660	Loss
CAMK_MAPKAPK_MNK_MKNK2_ST	Q15149	PLEC	Q9HBH9	MKNK2	S4630	T4632I	4632	Missense	proximal	2	no	18.991	19.151	EPSD	TCGA;COSMIC	18.660	Up-regulation
CAMK_MAPKAPK_MNK_MKNK2_ST	Q15149	PLEC	Q9HBH9	MKNK2	S4642	A4636V	4636	Missense	distal	-6	no	30.335	30.266	PhosphoSitePlus	TCGA;COSMIC	18.660	Down-regulation
CAMK_PIM_PIM3_ST	Q92934	BAD	Q86V86	PIM3	S57	G62E	62	Missense	distal	5	no	4.226	4.131	EPSD	TCGA;ICGC	3.716	Down-regulation
CAMK_PIM_PIM3_ST	Q92934	BAD	Q86V86	PIM3	S75	S71I	71	Missense	distal	-4	no	9.418	9.456	PhosphoSitePlus	TCGA;ICGC;COSMIC	3.716	Up-regulation
CAMK_PIM_PIM3_ST	Q92934	BAD	Q86V86	PIM3	S99	A100T	100	Missense	proximal	1	no	4.680	4.665	EPSD	TCGA;ICGC;COSMIC	3.716	Down-regulation
CAMK_PIM_PIM3_ST	Q92934	BAD	Q86V86	PIM3	S134	R131H	131	Missense	distal	-3	no	4.190	2.701	EPSD	TCGA;ICGC;COSMIC	3.716	Loss
CAMK_PIM_PIM3_ST	Q92934	BAD	Q86V86	PIM3	S134	G136D	136	Missense	proximal	2	no	4.190	4.122	EPSD	TCGA;ICGC;COSMIC	3.716	Down-regulation
CAMK_PIM_PIM3_ST	Q92934	BAD	Q86V86	PIM3	S134	S134I	134	Missense	central	0	yes	4.190	0.000	EPSD	TCGA	3.716	Loss
CAMK_PIM_PIM3_ST	Q92934	BAD	Q86V86	PIM3	T137	R131H	131	Missense	distal	-6	no	4.733	5.380	EPSD	TCGA;ICGC;COSMIC	3.716	Up-regulation
CAMK_PIM_PIM3_ST	Q92934	BAD	Q86V86	PIM3	T137	G136D	136	Missense	proximal	-1	no	4.733	4.639	EPSD	TCGA;ICGC;COSMIC	3.716	Down-regulation
CAMK_PIM_PIM3_ST	Q92934	BAD	Q86V86	PIM3	T137	S134I	134	Missense	distal	-3	no	4.733	3.139	EPSD	TCGA	3.716	Loss
CAMK_PIM_PIM3_ST	P35568	IRS1	Q86V86	PIM3	S189	I182V	182	Missense	distal	-7	no	3.555	4.192	EPSD	TCGA;ICGC	3.716	Gain
CAMK_PIM_PIM3_ST	P35568	IRS1	Q86V86	PIM3	S270	E263K	263	Missense	distal	-7	no	4.559	4.861	EPSD	TCGA;ICGC;COSMIC	3.716	Up-regulation
CAMK_PIM_PIM3_ST	P35568	IRS1	Q86V86	PIM3	S270	K269N	269	Missense	proximal	-1	no	4.559	4.597	EPSD	TCGA;ICGC;COSMIC	3.716	Up-regulation
CAMK_PIM_PIM3_ST	P35568	IRS1	Q86V86	PIM3	S270	P266S	266	Missense	distal	-4	no	4.559	4.549	EPSD	TCGA;ICGC;COSMIC	3.716	Down-regulation
CAMK_PIM_PIM3_ST	P35568	IRS1	Q86V86	PIM3	S270	C276F	276	Missense	distal	6	no	4.559	4.536	EPSD	TCGA;ICGC;COSMIC	3.716	Down-regulation
CAMK_PIM_PIM3_ST	P35568	IRS1	Q86V86	PIM3	S270	N275S	275	Missense	distal	5	no	4.559	4.569	EPSD	TCGA;ICGC;COSMIC	3.716	Up-regulation
CAMK_PIM_PIM3_ST	P35568	IRS1	Q86V86	PIM3	S307	A314G	314	Missense	distal	7	no	4.171	4.319	EPSD	TCGA;ICGC;COSMIC	3.716	Up-regulation
CAMK_PIM_PIM3_ST	P35568	IRS1	Q86V86	PIM3	T309	A314G	314	Missense	distal	5	no	4.582	4.614	EPSD	TCGA;ICGC;COSMIC	3.716	Up-regulation
CAMK_PIM_PIM3_ST	P35568	IRS1	Q86V86	PIM3	S330	R327H	327	Missense	distal	-3	no	4.493	3.004	EPSD	TCGA;ICGC	3.716	Loss
CAMK_PIM_PIM3_ST	P35568	IRS1	Q86V86	PIM3	S330	D331V	331	Missense	proximal	1	no	4.493	4.444	EPSD	TCGA;ICGC;COSMIC	3.716	Down-regulation
CAMK_PIM_PIM3_ST	P35568	IRS1	Q86V86	PIM3	S330	T335I	335	Missense	distal	5	no	4.493	4.352	EPSD	TCGA;ICGC;COSMIC	3.716	Down-regulation
CAMK_PIM_PIM3_ST	P35568	IRS1	Q86V86	PIM3	S330	A328T	328	Missense	proximal	-2	no	4.493	4.553	EPSD	TCGA;ICGC;COSMIC	3.716	Up-regulation
CAMK_PIM_PIM3_ST	P35568	IRS1	Q86V86	PIM3	S330	S330N	330	Missense	central	0	yes	4.493	0.000	EPSD	TCGA;ICGC;COSMIC	3.716	Loss
CAMK_PIM_PIM3_ST	P35568	IRS1	Q86V86	PIM3	S330	S323A	323	Missense	distal	-7	no	4.493	4.659	EPSD	TCGA;ICGC;COSMIC	3.716	Up-regulation
CAMK_PIM_PIM3_ST	P35568	IRS1	Q86V86	PIM3	T335	D331V	331	Missense	distal	-4	no	4.036	3.892	EPSD	TCGA;ICGC;COSMIC	3.716	Down-regulation
CAMK_PIM_PIM3_ST	P35568	IRS1	Q86V86	PIM3	T335	T335I	335	Missense	central	0	yes	4.036	0.000	EPSD	TCGA;ICGC;COSMIC	3.716	Loss
CAMK_PIM_PIM3_ST	P35568	IRS1	Q86V86	PIM3	T335	R338H	338	Missense	distal	3	no	4.036	4.730	EPSD	TCGA;ICGC;COSMIC	3.716	Up-regulation
CAMK_PIM_PIM3_ST	P35568	IRS1	Q86V86	PIM3	T335	R338C	338	Missense	distal	3	no	4.036	4.448	EPSD	TCGA;ICGC;COSMIC	3.716	Up-regulation
CAMK_PIM_PIM3_ST	P35568	IRS1	Q86V86	PIM3	T335	A328T	328	Missense	distal	-7	no	4.036	3.453	EPSD	TCGA;ICGC;COSMIC	3.716	Loss
CAMK_PIM_PIM3_ST	P35568	IRS1	Q86V86	PIM3	T335	S330N	330	Missense	distal	-5	no	4.036	3.707	EPSD	TCGA;ICGC;COSMIC	3.716	Loss
CAMK_PIM_PIM3_ST	P35568	IRS1	Q86V86	PIM3	S341	T335I	335	Missense	distal	-6	no	4.644	4.934	EPSD	TCGA;ICGC;COSMIC	3.716	Up-regulation
CAMK_PIM_PIM3_ST	P35568	IRS1	Q86V86	PIM3	S341	R338H	338	Missense	distal	-3	no	4.644	3.155	EPSD	TCGA;ICGC;COSMIC	3.716	Loss
CAMK_PIM_PIM3_ST	P35568	IRS1	Q86V86	PIM3	S341	R338C	338	Missense	distal	-3	no	4.644	2.139	EPSD	TCGA;ICGC;COSMIC	3.716	Loss
CAMK_PIM_PIM3_ST	P35568	IRS1	Q86V86	PIM3	S341	P346H	346	Missense	distal	5	no	4.644	4.519	EPSD	TCGA;ICGC	3.716	Down-regulation
CAMK_PIM_PIM3_ST	P35568	IRS1	Q86V86	PIM3	S348	P346H	346	Missense	proximal	-2	no	4.321	4.337	EPSD	TCGA;ICGC	3.716	Up-regulation
CAMK_PIM_PIM3_ST	P35568	IRS1	Q86V86	PIM3	S374	P378S	378	Missense	distal	4	no	3.618	3.821	EPSD	TCGA;ICGC;COSMIC	3.716	Gain
CAMK_PIM_PIM3_ST	P35568	IRS1	Q86V86	PIM3	T397	S395C	395	Missense	proximal	-2	no	4.342	4.486	EPSD	TCGA;ICGC;COSMIC	3.716	Up-regulation
CAMK_PIM_PIM3_ST	P35568	IRS1	Q86V86	PIM3	S398	S395C	395	Missense	distal	-3	no	4.113	2.832	EPSD	TCGA;ICGC;COSMIC	3.716	Loss
CAMK_PIM_PIM3_ST	P35568	IRS1	Q86V86	PIM3	S415	R411Q	411	Missense	distal	-4	no	4.182	4.814	EPSD	TCGA;ICGC	3.716	Up-regulation
CAMK_PIM_PIM3_ST	P35568	IRS1	Q86V86	PIM3	S433	S428L	428	Missense	distal	-5	no	3.861	4.291	EPSD	TCGA;ICGC;COSMIC	3.716	Up-regulation
CAMK_PIM_PIM3_ST	P35568	IRS1	Q86V86	PIM3	S433	F438V	438	Missense	distal	5	no	3.861	3.926	EPSD	TCGA;ICGC;COSMIC	3.716	Up-regulation
CAMK_PIM_PIM3_ST	P35568	IRS1	Q86V86	PIM3	S444	F438V	438	Missense	distal	-6	no	3.688	3.983	EPSD	TCGA;ICGC;COSMIC	3.716	Gain
CAMK_PIM_PIM3_ST	P35568	IRS1	Q86V86	PIM3	S444	V445I	445	Missense	proximal	1	no	3.688	3.830	EPSD	TCGA;ICGC;COSMIC	3.716	Gain
CAMK_PIM_PIM3_ST	P35568	IRS1	Q86V86	PIM3	T525	R520W	520	Missense	distal	-5	no	4.253	2.813	EPSD	TCGA;ICGC;COSMIC	3.716	Loss
CAMK_PIM_PIM3_ST	P35568	IRS1	Q86V86	PIM3	T525	R522Q	522	Missense	distal	-3	no	4.253	2.713	EPSD	TCGA;ICGC;COSMIC	3.716	Loss
CAMK_PIM_PIM3_ST	P35568	IRS1	Q86V86	PIM3	T525	R520Q	520	Missense	distal	-5	no	4.253	3.885	EPSD	TCGA;ICGC;COSMIC	3.716	Down-regulation
CAMK_PIM_PIM3_ST	P35568	IRS1	Q86V86	PIM3	S527	R520W	520	Missense	distal	-7	no	3.958	4.212	EPSD	TCGA;ICGC;COSMIC	3.716	Up-regulation
CAMK_PIM_PIM3_ST	P35568	IRS1	Q86V86	PIM3	S527	R522Q	522	Missense	distal	-5	no	3.958	3.590	EPSD	TCGA;ICGC;COSMIC	3.716	Loss
CAMK_PIM_PIM3_ST	P35568	IRS1	Q86V86	PIM3	S527	R520Q	520	Missense	distal	-7	no	3.958	4.247	EPSD	TCGA;ICGC;COSMIC	3.716	Up-regulation
CAMK_PIM_PIM3_ST	P35568	IRS1	Q86V86	PIM3	T579	S581Y	581	Missense	proximal	2	no	4.333	4.400	EPSD	TCGA;ICGC;COSMIC	3.716	Up-regulation
CAMK_PIM_PIM3_ST	P35568	IRS1	Q86V86	PIM3	S603	H607R	607	Missense	distal	4	no	4.669	4.247	EPSD	TCGA;ICGC	3.716	Down-regulation
CAMK_PIM_PIM3_ST	P35568	IRS1	Q86V86	PIM3	S603	R600C	600	Missense	distal	-3	no	4.669	2.164	EPSD	TCGA;ICGC;COSMIC	3.716	Loss
CAMK_PIM_PIM3_ST	P35568	IRS1	Q86V86	PIM3	S745	N742D	742	Missense	distal	-3	no	3.277	4.261	EPSD	TCGA;ICGC;COSMIC	3.716	Gain
CAMK_PIM_PIM3_ST	P35568	IRS1	Q86V86	PIM3	T793	R797C	797	Missense	distal	4	no	4.369	4.819	EPSD	TCGA;ICGC;COSMIC	3.716	Up-regulation
CAMK_PIM_PIM3_ST	P35568	IRS1	Q86V86	PIM3	S794	R797C	797	Missense	distal	3	no	4.487	4.900	EPSD	TCGA;ICGC;COSMIC	3.716	Up-regulation
CAMK_PIM_PIM3_ST	P35568	IRS1	Q86V86	PIM3	S795	R797C	797	Missense	proximal	2	no	4.451	4.484	EPSD	TCGA;ICGC;COSMIC	3.716	Up-regulation
CAMK_PIM_PIM3_ST	P35568	IRS1	Q86V86	PIM3	T859	A856T	856	Missense	distal	-3	no	4.638	4.194	EPSD	TCGA;ICGC;COSMIC	3.716	Down-regulation
CAMK_PIM_PIM3_ST	P35568	IRS1	Q86V86	PIM3	T859	R857W	857	Missense	proximal	-2	no	4.638	4.956	EPSD	TCGA;ICGC;COSMIC	3.716	Up-regulation
CAMK_PIM_PIM3_ST	P35568	IRS1	Q86V86	PIM3	T870	E876Q	876	Missense	distal	6	no	4.657	4.533	EPSD	TCGA;ICGC;COSMIC	3.716	Down-regulation
CAMK_PIM_PIM3_ST	P35568	IRS1	Q86V86	PIM3	S1105	S1109C	1109	Missense	distal	4	no	4.113	3.899	EPSD	TCGA;ICGC;COSMIC	3.716	Down-regulation
CAMK_PIM_PIM3_ST	P35568	IRS1	Q86V86	PIM3	T1107	S1109C	1109	Missense	proximal	2	no	3.675	3.764	EPSD	TCGA;ICGC;COSMIC	3.716	Gain
TK_Src_SrcB_LCK_Y	P06127	CD5	P06239	LCK	Y453	P456H	456	Missense	distal	3	no	8.886	9.680	PhosphoSitePlus;EPSD	TCGA;ICGC;COSMIC	5.050	Up-regulation
TK_Src_SrcB_LCK_Y	P06127	CD5	P06239	LCK	Y453	V449M	449	Missense	distal	-4	no	8.886	9.114	PhosphoSitePlus;EPSD	TCGA;ICGC;COSMIC	5.050	Up-regulation
TK_Src_SrcB_LCK_Y	P06127	CD5	P06239	LCK	Y453	E452K	452	Missense	proximal	-1	no	8.886	6.031	PhosphoSitePlus;EPSD	TCGA;ICGC;COSMIC	5.050	Down-regulation
TK_Src_SrcB_LCK_Y	P06127	CD5	P06239	LCK	Y453	S447P	447	Missense	distal	-6	no	8.886	8.669	PhosphoSitePlus;EPSD	TCGA;ICGC	5.050	Down-regulation
TK_Src_SrcB_LCK_Y	P06127	CD5	P06239	LCK	Y487	S485G	485	Missense	proximal	-2	no	6.371	6.290	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	5.050	Down-regulation
TK_Src_SrcB_LCK_Y	P06127	CD5	P06239	LCK	Y487	S483F	483	Missense	distal	-4	no	6.371	5.824	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	5.050	Down-regulation
TK_Src_SrcB_LCK_Y	P16885	PLCG2	P06239	LCK	Y743	E738K	738	Missense	distal	-5	no	5.745	5.085	EPSD	TCGA;ICGC;COSMIC;GDSC;CCLE	5.050	Down-regulation
TK_Src_SrcB_LCK_Y	P16885	PLCG2	P06239	LCK	Y753	D754N	754	Missense	proximal	1	no	5.520	4.929	PhosphoSitePlus;EPSD	TCGA;ICGC;COSMIC	5.050	Loss
TK_Src_SrcB_LCK_Y	P16885	PLCG2	P06239	LCK	Y753	D754A	754	Missense	proximal	1	no	5.520	4.431	PhosphoSitePlus;EPSD	TCGA;ICGC;COSMIC	5.050	Loss
TK_Src_SrcB_LCK_Y	P16885	PLCG2	P06239	LCK	Y753	V755I	755	Missense	proximal	2	no	5.520	5.098	PhosphoSitePlus;EPSD	TCGA;ICGC;COSMIC	5.050	Down-regulation
TK_Src_SrcB_LCK_Y	P16885	PLCG2	P06239	LCK	Y759	D754N	754	Missense	distal	-5	no	5.707	5.571	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	5.050	Down-regulation
TK_Src_SrcB_LCK_Y	P16885	PLCG2	P06239	LCK	Y759	D754A	754	Missense	distal	-5	no	5.707	5.806	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	5.050	Up-regulation
TK_Src_SrcB_LCK_Y	P16885	PLCG2	P06239	LCK	Y759	S763N	763	Missense	distal	4	no	5.707	5.412	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	5.050	Down-regulation
TK_Src_SrcB_LCK_Y	P16885	PLCG2	P06239	LCK	Y759	V755I	755	Missense	distal	-4	no	5.707	5.653	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	5.050	Down-regulation
TK_Src_SrcB_LCK_Y	P16885	PLCG2	P06239	LCK	Y858	Q865E	865	Missense	distal	7	no	6.096	6.097	EPSD	TCGA;ICGC;COSMIC	5.050	Up-regulation
TK_Src_SrcB_LCK_Y	P16885	PLCG2	P06239	LCK	Y858	N856T	856	Missense	proximal	-2	no	6.096	5.611	EPSD	TCGA;ICGC;COSMIC	5.050	Down-regulation
TK_Src_SrcB_LCK_Y	P16885	PLCG2	P06239	LCK	Y1197	E1194D	1194	Missense	distal	-3	no	6.477	7.048	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	5.050	Up-regulation
TK_Src_SrcB_LCK_Y	P16885	PLCG2	P06239	LCK	Y1197	S1198A	1198	Missense	proximal	1	no	6.477	6.412	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	5.050	Down-regulation
TK_Src_SrcB_LCK_Y	P16885	PLCG2	P06239	LCK	Y1197	R1201H	1201	Missense	distal	4	no	6.477	6.140	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	5.050	Down-regulation
TK_Src_SrcB_LCK_Y	P14784	IL2RB	P06239	LCK	Y384	D391N	391	Missense	distal	7	no	5.471	5.331	EPSD;PhosphoSitePlus	TCGA;ICGC	5.050	Down-regulation
TK_Src_SrcB_LCK_Y	P14784	IL2RB	P06239	LCK	Y384	E390K	390	Missense	distal	6	no	5.471	6.497	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC;GDSC;CCLE	5.050	Up-regulation
TK_Src_SrcB_LCK_Y	P14784	IL2RB	P06239	LCK	Y387	D391N	391	Missense	distal	4	no	6.102	5.658	EPSD;PhosphoSitePlus	TCGA;ICGC	5.050	Down-regulation
TK_Src_SrcB_LCK_Y	P14784	IL2RB	P06239	LCK	Y387	E390K	390	Missense	distal	3	no	6.102	5.174	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC;GDSC;CCLE	5.050	Down-regulation
TK_Src_SrcB_LCK_Y	P14784	IL2RB	P06239	LCK	Y418	A417T	417	Missense	proximal	-1	no	6.809	7.688	PhosphoSitePlus;EPSD	TCGA;ICGC;COSMIC	5.050	Up-regulation
TK_Src_SrcB_LCK_Y	P14784	IL2RB	P06239	LCK	Y418	E414K	414	Missense	distal	-4	no	6.809	6.006	PhosphoSitePlus;EPSD	TCGA;ICGC;COSMIC	5.050	Down-regulation
TK_Src_SrcB_LCK_Y	P14784	IL2RB	P06239	LCK	Y418	P422L	422	Missense	distal	4	no	6.809	6.394	PhosphoSitePlus;EPSD	TCGA;ICGC;COSMIC	5.050	Down-regulation
TK_Src_SrcB_LCK_Y	P14784	IL2RB	P06239	LCK	Y418	G413E	413	Missense	distal	-5	no	6.809	7.334	PhosphoSitePlus;EPSD	TCGA;ICGC;COSMIC	5.050	Up-regulation
TK_Src_SrcB_LCK_Y	P29353	SHC1	P06239	LCK	Y349	P354A	354	Missense	distal	5	no	8.905	8.869	EPSD	TCGA;COSMIC	5.050	Down-regulation
TK_Src_SrcB_LCK_Y	P29353	SHC1	P06239	LCK	Y349	F353L	353	Missense	distal	4	no	8.905	9.013	EPSD	TCGA;COSMIC	5.050	Up-regulation
TK_Src_SrcB_LCK_Y	P29353	SHC1	P06239	LCK	Y349	P344S	344	Missense	distal	-5	no	8.905	8.858	EPSD	TCGA;COSMIC	5.050	Down-regulation
TK_Src_SrcB_LCK_Y	P29353	SHC1	P06239	LCK	Y350	P354A	354	Missense	distal	4	no	7.492	7.630	EPSD	TCGA;COSMIC	5.050	Up-regulation
TK_Src_SrcB_LCK_Y	P29353	SHC1	P06239	LCK	Y350	E357K	357	Missense	distal	7	no	7.492	7.331	EPSD	TCGA;COSMIC	5.050	Down-regulation
TK_Src_SrcB_LCK_Y	P29353	SHC1	P06239	LCK	Y350	F353L	353	Missense	distal	3	no	7.492	7.771	EPSD	TCGA;COSMIC	5.050	Up-regulation
TK_Src_SrcB_LCK_Y	P29353	SHC1	P06239	LCK	Y350	P344S	344	Missense	distal	-6	no	7.492	7.709	EPSD	TCGA;COSMIC	5.050	Up-regulation
TK_Src_SrcB_LCK_Y	P20963	CD247	P06239	LCK	Y72	N69S	69	Missense	distal	-3	no	6.145	5.192	EPSD	TCGA;ICGC;COSMIC	5.050	Down-regulation
TK_Src_SrcB_LCK_Y	P20963	CD247	P06239	LCK	Y72	N69K	69	Missense	distal	-3	no	6.145	5.266	EPSD	TCGA;ICGC;COSMIC	5.050	Down-regulation
TK_Src_SrcB_LCK_Y	P20963	CD247	P06239	LCK	Y83	R90C	90	Missense	distal	7	no	5.558	5.145	EPSD	TCGA;ICGC;COSMIC	5.050	Down-regulation
TK_Src_SrcB_LCK_Y	P20963	CD247	P06239	LCK	Y83	V85A	85	Missense	proximal	2	no	5.558	6.859	EPSD	TCGA;ICGC;COSMIC	5.050	Up-regulation
TK_Src_SrcB_LCK_Y	P20963	CD247	P06239	LCK	Y83	D84Y	84	Missense	proximal	1	no	5.558	4.742	EPSD	TCGA;ICGC;COSMIC	5.050	Loss
TK_Src_SrcB_LCK_Y	P20963	CD247	P06239	LCK	Y83	R89K	89	Missense	distal	6	no	5.558	6.162	EPSD	TCGA;ICGC;COSMIC	5.050	Up-regulation
TK_Src_SrcB_LCK_Y	P20963	CD247	P06239	LCK	Y83	D84N	84	Missense	proximal	1	no	5.558	4.967	EPSD	TCGA;ICGC;COSMIC	5.050	Loss
TK_Src_SrcB_LCK_Y	P20963	CD247	P06239	LCK	Y83	R89I	89	Missense	distal	6	no	5.558	5.926	EPSD	TCGA;ICGC;COSMIC	5.050	Up-regulation
TK_Src_SrcB_LCK_Y	P20963	CD247	P06239	LCK	Y83	R90H	90	Missense	distal	7	no	5.558	5.564	EPSD	TCGA;ICGC;COSMIC	5.050	Up-regulation
TK_Src_SrcB_LCK_Y	P20963	CD247	P06239	LCK	Y111	E113K	113	Missense	proximal	2	no	7.974	7.947	EPSD	TCGA;ICGC;COSMIC	5.050	Down-regulation
TK_Src_SrcB_LCK_Y	P20963	CD247	P06239	LCK	Y111	Q107K	107	Missense	distal	-4	no	7.974	7.931	EPSD	TCGA;ICGC;COSMIC	5.050	Down-regulation
TK_Src_SrcB_LCK_Y	P20963	CD247	P06239	LCK	Y111	L114P	114	Missense	distal	3	no	7.974	7.258	EPSD	TCGA;ICGC;COSMIC	5.050	Down-regulation
TK_Src_SrcB_LCK_Y	P20963	CD247	P06239	LCK	Y142	L145H	145	Missense	distal	3	no	8.002	8.081	PhosphoSitePlus	TCGA;ICGC;COSMIC	5.050	Up-regulation
TK_Src_SrcB_LCK_Y	P20963	CD247	P06239	LCK	Y142	G140D	140	Missense	proximal	-2	no	8.002	8.934	PhosphoSitePlus	TCGA;ICGC	5.050	Up-regulation
TK_Src_SrcB_LCK_Y	P20963	CD247	P06239	LCK	Y142	H138Q	138	Missense	distal	-4	no	8.002	8.250	PhosphoSitePlus	TCGA;ICGC;COSMIC	5.050	Up-regulation
TK_Src_SrcB_LCK_Y	P20963	CD247	P06239	LCK	Y142	D139N	139	Missense	distal	-3	no	8.002	7.027	PhosphoSitePlus	TCGA;ICGC;COSMIC;GDSC;CCLE	5.050	Down-regulation
TK_Src_SrcB_LCK_Y	P20963	CD247	P06239	LCK	Y153	A155T	155	Missense	proximal	2	no	7.641	7.071	EPSD	TCGA;ICGC;COSMIC;GDSC;CCLE	5.050	Down-regulation
TK_Src_SrcB_LCK_Y	P20963	CD247	P06239	LCK	Y153	D154N	154	Missense	proximal	1	no	7.641	7.050	EPSD	TCGA;ICGC;COSMIC	5.050	Down-regulation
TK_Src_SrcB_LCK_Y	Q9BWW4	SSBP3	P06239	LCK	Y25	V31A	31	Missense	distal	6	no	5.842	5.514	PhosphoSitePlus;EPSD	TCGA;ICGC;COSMIC	5.050	Down-regulation
TK_Src_SrcB_LCK_Y	P43403	ZAP70	P06239	LCK	Y69	R63C	63	Missense	distal	-6	no	6.106	5.043	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	5.050	Loss
TK_Src_SrcB_LCK_Y	P43403	ZAP70	P06239	LCK	Y126	R124H	124	Missense	proximal	-2	no	6.232	5.680	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	5.050	Down-regulation
TK_Src_SrcB_LCK_Y	P43403	ZAP70	P06239	LCK	Y126	V127M	127	Missense	proximal	1	no	6.232	6.675	EPSD;PhosphoSitePlus	TCGA;ICGC;CCLE	5.050	Up-regulation
TK_Src_SrcB_LCK_Y	P43403	ZAP70	P06239	LCK	Y126	Q129H	129	Missense	distal	3	no	6.232	7.340	EPSD;PhosphoSitePlus	TCGA;ICGC	5.050	Up-regulation
TK_Src_SrcB_LCK_Y	P43403	ZAP70	P06239	LCK	Y126	R128C	128	Missense	proximal	2	no	6.232	5.170	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	5.050	Down-regulation
TK_Src_SrcB_LCK_Y	P43403	ZAP70	P06239	LCK	Y178	S179F	179	Missense	proximal	1	no	7.005	6.659	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	5.050	Down-regulation
TK_Src_SrcB_LCK_Y	P43403	ZAP70	P06239	LCK	Y178	E174V	174	Missense	distal	-4	no	7.005	6.103	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	5.050	Down-regulation
TK_Src_SrcB_LCK_Y	P43403	ZAP70	P06239	LCK	Y178	A181V	181	Missense	distal	3	no	7.005	6.859	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	5.050	Down-regulation
TK_Src_SrcB_LCK_Y	P43403	ZAP70	P06239	LCK	Y178	G185S	185	Missense	distal	7	no	7.005	7.097	EPSD;PhosphoSitePlus	TCGA;ICGC	5.050	Up-regulation
TK_Src_SrcB_LCK_Y	P43403	ZAP70	P06239	LCK	Y178	D184N	184	Missense	distal	6	no	7.005	7.332	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	5.050	Up-regulation
TK_Src_SrcB_LCK_Y	P43403	ZAP70	P06239	LCK	Y315	V314M	314	Missense	proximal	-1	no	7.852	7.356	PhosphoSitePlus;EPSD	TCGA;ICGC;COSMIC	5.050	Down-regulation
TK_Src_SrcB_LCK_Y	P43403	ZAP70	P06239	LCK	Y315	D321N	321	Missense	distal	6	no	7.852	8.179	PhosphoSitePlus;EPSD	TCGA;ICGC;COSMIC	5.050	Up-regulation
TK_Src_SrcB_LCK_Y	P43403	ZAP70	P06239	LCK	Y319	E324K	324	Missense	distal	5	no	8.248	8.352	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	5.050	Up-regulation
TK_Src_SrcB_LCK_Y	P43403	ZAP70	P06239	LCK	Y319	V314M	314	Missense	distal	-5	no	8.248	8.886	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	5.050	Up-regulation
TK_Src_SrcB_LCK_Y	P43403	ZAP70	P06239	LCK	Y319	D321N	321	Missense	proximal	2	no	8.248	8.502	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	5.050	Up-regulation
TK_Src_SrcB_LCK_Y	P43403	ZAP70	P06239	LCK	Y357	R360H	360	Missense	distal	3	no	4.523	5.650	EPSD	TCGA;ICGC;COSMIC	5.050	Gain
TK_Src_SrcB_LCK_Y	P43403	ZAP70	P06239	LCK	Y492	R496H	496	Missense	distal	4	no	8.350	8.013	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	5.050	Down-regulation
TK_Src_SrcB_LCK_Y	P43403	ZAP70	P06239	LCK	Y492	Y492C	492	Missense	central	0	yes	8.350	0.000	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	5.050	Loss
TK_Src_SrcB_LCK_Y	P43403	ZAP70	P06239	LCK	Y492	A485S	485	Missense	distal	-7	no	8.350	8.231	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	5.050	Down-regulation
TK_Src_SrcB_LCK_Y	P43403	ZAP70	P06239	LCK	Y493	R496H	496	Missense	distal	3	no	6.652	7.778	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	5.050	Up-regulation
TK_Src_SrcB_LCK_Y	P43403	ZAP70	P06239	LCK	Y493	Y492C	492	Missense	proximal	-1	no	6.652	6.199	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	5.050	Down-regulation
TK_Src_SrcB_LCK_Y	P43403	ZAP70	P06239	LCK	Y569	E567K	567	Missense	proximal	-2	no	7.233	6.663	EPSD	TCGA;ICGC;COSMIC;GDSC	5.050	Down-regulation
TK_Src_SrcB_LCK_Y	P20138	CD33	P06239	LCK	Y340	E333D	333	Missense	distal	-7	no	6.770	6.422	PhosphoSitePlus	TCGA;COSMIC	5.050	Down-regulation
TK_Src_SrcB_LCK_Y	P20138	CD33	P06239	LCK	Y340	M334I	334	Missense	distal	-6	no	6.770	5.863	PhosphoSitePlus	TCGA;COSMIC	5.050	Down-regulation
TK_Src_SrcB_LCK_Y	P20138	CD33	P06239	LCK	Y340	L338M	338	Missense	proximal	-2	no	6.770	7.098	PhosphoSitePlus	TCGA	5.050	Up-regulation
TK_Src_SrcB_LCK_Y	P20138	CD33	P06239	LCK	Y340	A341T	341	Missense	proximal	1	no	6.770	7.298	PhosphoSitePlus	TCGA;COSMIC	5.050	Up-regulation
TK_Src_SrcB_LCK_Y	P20138	CD33	P06239	LCK	Y340	H339R	339	Missense	proximal	-1	no	6.770	5.765	PhosphoSitePlus	TCGA;COSMIC	5.050	Down-regulation
TK_Src_SrcB_LCK_Y	P20138	CD33	P06239	LCK	Y340	D335N	335	Missense	distal	-5	no	6.770	6.634	PhosphoSitePlus	TCGA	5.050	Down-regulation
TK_Src_SrcB_LCK_Y	P20138	CD33	P06239	LCK	Y358	S355Y	355	Missense	distal	-3	no	4.323	5.093	EPSD	TCGA;COSMIC	5.050	Gain
TK_Src_SrcB_LCK_Y	Q8IVM0	CCDC50	P06239	LCK	Y144	A141T	141	Missense	distal	-3	no	4.969	5.743	EPSD	TCGA;ICGC;COSMIC	5.050	Gain
TK_Src_SrcB_LCK_Y	P06239	LCK	P06239	LCK	Y394	E393G	393	Missense	proximal	-1	no	8.757	6.904	EPSD;PhosphoSitePlus	TCGA;COSMIC	5.050	Down-regulation
TK_Src_SrcB_LCK_Y	P06239	LCK	P06239	LCK	Y394	E393K	393	Missense	proximal	-1	no	8.757	5.902	EPSD;PhosphoSitePlus	TCGA;COSMIC	5.050	Down-regulation
TK_Src_SrcB_LCK_Y	P06239	LCK	P06239	LCK	Y394	A396T	396	Missense	proximal	2	no	8.757	8.187	EPSD;PhosphoSitePlus	TCGA;COSMIC;CCLE	5.050	Down-regulation
TK_Src_SrcB_LCK_Y	P06239	LCK	P06239	LCK	Y505	Y505C	505	Missense	central	0	yes	6.755	0.000	PhosphoSitePlus;EPSD	TCGA;ICGC	5.050	Loss
TK_Src_SrcB_LCK_Y	Q8IWV1	LAX1	P06239	LCK	Y93	N91H	91	Missense	proximal	-2	no	5.216	4.339	EPSD	TCGA;COSMIC	5.050	Loss
TK_Src_SrcB_LCK_Y	P15498	VAV1	P06239	LCK	Y142	D140Y	140	Missense	proximal	-2	no	7.950	6.863	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	5.050	Down-regulation
TK_Src_SrcB_LCK_Y	P15498	VAV1	P06239	LCK	Y160	V163M	163	Missense	distal	3	no	10.123	10.338	PhosphoSitePlus;EPSD	TCGA	5.050	Up-regulation
TK_Src_SrcB_LCK_Y	P15498	VAV1	P06239	LCK	Y160	E164D	164	Missense	distal	4	no	10.123	9.870	PhosphoSitePlus;EPSD	TCGA;ICGC	5.050	Down-regulation
TK_Src_SrcB_LCK_Y	P15498	VAV1	P06239	LCK	Y174	D171N	171	Missense	distal	-3	no	10.500	9.525	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC;CCLE	5.050	Down-regulation
TK_Src_SrcB_LCK_Y	P15498	VAV1	P06239	LCK	Y174	A168V	168	Missense	distal	-6	no	10.500	9.682	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC;CCLE	5.050	Down-regulation
TK_Src_SrcB_LCK_Y	P15498	VAV1	P06239	LCK	Y174	D171E	171	Missense	distal	-3	no	10.500	9.929	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	5.050	Down-regulation
TK_Src_SrcB_LCK_Y	P15498	VAV1	P06239	LCK	Y267	A263T	263	Missense	distal	-4	no	4.862	5.077	EPSD	TCGA;ICGC;COSMIC;GDSC;CCLE	5.050	Gain
TK_Src_SrcB_LCK_Y	P15498	VAV1	P06239	LCK	Y603	G605R	605	Missense	proximal	2	no	5.374	5.183	EPSD	TCGA;ICGC;COSMIC	5.050	Down-regulation
TK_Src_SrcB_LCK_Y	P29350	PTPN6	P06239	LCK	Y509	Y505H	505	Missense	distal	-4	no	5.697	5.465	EPSD	TCGA;COSMIC	5.050	Down-regulation
TK_Src_SrcB_LCK_Y	P29350	PTPN6	P06239	LCK	Y564	E561Q	561	Missense	distal	-3	no	10.692	9.924	PhosphoSitePlus;EPSD	TCGA;ICGC;COSMIC	5.050	Down-regulation
TK_Src_SrcB_LCK_Y	Q13094	LCP2	P06239	LCK	Y113	S115R	115	Missense	proximal	2	no	8.611	7.757	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	5.050	Down-regulation
TK_Src_SrcB_LCK_Y	Q13094	LCP2	P06239	LCK	Y113	E109D	109	Missense	distal	-4	no	8.611	8.535	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	5.050	Down-regulation
TK_Src_SrcB_LCK_Y	Q13094	LCP2	P06239	LCK	Y113	D111N	111	Missense	proximal	-2	no	8.611	8.017	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC;GDSC;CCLE	5.050	Down-regulation
TK_Src_SrcB_LCK_Y	Q13094	LCP2	P06239	LCK	Y128	D127N	127	Missense	proximal	-1	no	9.064	6.551	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	5.050	Down-regulation
TK_Src_SrcB_LCK_Y	Q13094	LCP2	P06239	LCK	Y128	E123K	123	Missense	distal	-5	no	9.064	8.404	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	5.050	Down-regulation
TK_Src_SrcB_LCK_Y	Q13094	LCP2	P06239	LCK	Y128	N132S	132	Missense	distal	4	no	9.064	9.358	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	5.050	Up-regulation
TK_Src_SrcB_LCK_Y	Q13094	LCP2	P06239	LCK	Y128	G122V	122	Missense	distal	-6	no	9.064	8.835	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	5.050	Down-regulation
TK_Src_SrcB_LCK_Y	Q13094	LCP2	P06239	LCK	Y145	A143E	143	Missense	proximal	-2	no	8.816	9.623	PhosphoSitePlus;EPSD	TCGA;ICGC	5.050	Up-regulation
TK_Src_SrcB_LCK_Y	Q13094	LCP2	P06239	LCK	Y145	V139M	139	Missense	distal	-6	no	8.816	9.445	PhosphoSitePlus;EPSD	TCGA;ICGC;COSMIC;CCLE	5.050	Up-regulation
TK_Src_SrcB_LCK_Y	Q13094	LCP2	P06239	LCK	Y145	D144E	144	Missense	proximal	-1	no	8.816	8.849	PhosphoSitePlus;EPSD	TCGA;ICGC;COSMIC	5.050	Up-regulation
TK_Src_SrcB_LCK_Y	Q13094	LCP2	P06239	LCK	Y483	R490Q	490	Missense	distal	7	no	6.119	6.202	EPSD	TCGA;COSMIC;GDSC;CCLE	5.050	Up-regulation
TK_Src_SrcB_LCK_Y	Q13094	LCP2	P06239	LCK	Y483	G488R	488	Missense	distal	5	no	6.119	6.064	EPSD	TCGA;COSMIC	5.050	Down-regulation
TK_Src_SrcB_LCK_Y	Q8N1K5	THEMIS	P06239	LCK	Y540	M543T	543	Missense	distal	3	no	8.032	7.157	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	5.050	Down-regulation
TK_Src_SrcB_LCK_Y	Q8N1K5	THEMIS	P06239	LCK	Y540	E547K	547	Missense	distal	7	no	8.032	7.871	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	5.050	Down-regulation
TK_Src_SrcB_LCK_Y	Q8N1K5	THEMIS	P06239	LCK	Y540	Q539K	539	Missense	proximal	-1	no	8.032	6.305	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	5.050	Down-regulation
TK_Src_SrcB_LCK_Y	Q8N1K5	THEMIS	P06239	LCK	Y540	R545I	545	Missense	distal	5	no	8.032	8.239	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	5.050	Up-regulation
TK_Src_SrcB_LCK_Y	Q8N1K5	THEMIS	P06239	LCK	Y541	M543T	543	Missense	proximal	2	no	6.248	6.146	PhosphoSitePlus;EPSD	TCGA;ICGC;COSMIC	5.050	Down-regulation
TK_Src_SrcB_LCK_Y	Q8N1K5	THEMIS	P06239	LCK	Y541	E547K	547	Missense	distal	6	no	6.248	7.274	PhosphoSitePlus;EPSD	TCGA;ICGC;COSMIC	5.050	Up-regulation
TK_Src_SrcB_LCK_Y	Q8N1K5	THEMIS	P06239	LCK	Y541	Q539K	539	Missense	proximal	-2	no	6.248	6.432	PhosphoSitePlus;EPSD	TCGA;ICGC;COSMIC	5.050	Up-regulation
TK_Src_SrcB_LCK_Y	Q8N1K5	THEMIS	P06239	LCK	Y541	R545I	545	Missense	distal	4	no	6.248	5.188	PhosphoSitePlus;EPSD	TCGA;ICGC;COSMIC	5.050	Down-regulation
TK_Src_SrcB_LCK_Y	Q16539	MAPK14	P06239	LCK	Y182	R186K	186	Missense	distal	4	no	7.120	6.783	EPSD	TCGA;ICGC;COSMIC	5.050	Down-regulation
TK_Src_SrcB_LCK_Y	Q16539	MAPK14	P06239	LCK	Y323	D324A	324	Missense	proximal	1	no	6.587	5.498	PhosphoSitePlus	TCGA;COSMIC	5.050	Down-regulation
TK_Src_SrcB_LCK_Y	P42229	STAT5A	P06239	LCK	Y171	E178D	178	Missense	distal	7	no	6.645	6.599	EPSD	TCGA;ICGC;COSMIC	5.050	Down-regulation
TK_Src_SrcB_LCK_Y	P42229	STAT5A	P06239	LCK	Y668	P674H	674	Missense	distal	6	no	5.431	4.996	EPSD	TCGA	5.050	Loss
TK_Src_SrcB_LCK_Y	P42229	STAT5A	P06239	LCK	Y668	R673H	673	Missense	distal	5	no	5.431	5.460	EPSD	TCGA;COSMIC;CCLE	5.050	Up-regulation
TK_Src_SrcB_LCK_Y	P42229	STAT5A	P06239	LCK	Y694	Q698P	698	Missense	distal	4	no	5.862	5.653	PhosphoSitePlus	TCGA;ICGC	5.050	Down-regulation
TK_Src_SrcB_LCK_Y	Q13291	SLAMF1	P06239	LCK	Y269	E274K	274	Missense	distal	5	no	5.449	5.552	EPSD	TCGA;ICGC;COSMIC	5.050	Up-regulation
TK_Src_SrcB_LCK_Y	Q13291	SLAMF1	P06239	LCK	Y269	E274G	274	Missense	distal	5	no	5.449	5.580	EPSD	TCGA;ICGC;COSMIC;GDSC;CCLE	5.050	Up-regulation
TK_Src_SrcB_LCK_Y	Q13291	SLAMF1	P06239	LCK	Y281	Q283E	283	Missense	proximal	2	no	5.141	5.680	EPSD	TCGA	5.050	Up-regulation
TK_Src_SrcB_LCK_Y	Q13291	SLAMF1	P06239	LCK	Y281	T279M	279	Missense	proximal	-2	no	5.141	4.616	EPSD	TCGA;ICGC;COSMIC	5.050	Loss
TK_Src_SrcB_LCK_Y	Q13291	SLAMF1	P06239	LCK	Y281	E274K	274	Missense	distal	-7	no	5.141	4.721	EPSD	TCGA;ICGC;COSMIC	5.050	Loss
TK_Src_SrcB_LCK_Y	Q13291	SLAMF1	P06239	LCK	Y281	E274G	274	Missense	distal	-7	no	5.141	4.652	EPSD	TCGA;ICGC;COSMIC;GDSC;CCLE	5.050	Loss
TK_Src_SrcB_LCK_Y	Q13291	SLAMF1	P06239	LCK	Y281	L278F	278	Missense	distal	-3	no	5.141	5.417	EPSD	TCGA;ICGC	5.050	Up-regulation
TK_Src_SrcB_LCK_Y	Q13291	SLAMF1	P06239	LCK	Y281	K286Q	286	Missense	distal	5	no	5.141	5.111	EPSD	TCGA;ICGC;COSMIC	5.050	Down-regulation
TK_Src_SrcB_LCK_Y	Q13291	SLAMF1	P06239	LCK	Y307	A309S	309	Missense	proximal	2	no	7.153	6.963	PhosphoSitePlus	TCGA;ICGC;COSMIC	5.050	Down-regulation
TK_Src_SrcB_LCK_Y	Q13291	SLAMF1	P06239	LCK	Y307	D301N	301	Missense	distal	-6	no	7.153	6.923	PhosphoSitePlus	TCGA;ICGC;COSMIC	5.050	Down-regulation
TK_Src_SrcB_LCK_Y	Q13444	ADAM15	P06239	LCK	Y735	S740F	740	Missense	distal	5	no	6.300	6.450	EPSD	TCGA;COSMIC	5.050	Up-regulation
TK_Src_SrcB_LCK_Y	Q13444	ADAM15	P06239	LCK	Y735	A738S	738	Missense	distal	3	no	6.300	5.976	EPSD	TCGA;COSMIC	5.050	Down-regulation
TK_Src_SrcB_LCK_Y	P22681	CBL	P06239	LCK	Y141	R139I	139	Missense	proximal	-2	no	6.165	5.310	EPSD	TCGA;ICGC;COSMIC	5.050	Down-regulation
TK_Src_SrcB_LCK_Y	P22681	CBL	P06239	LCK	Y141	E143D	143	Missense	proximal	2	no	6.165	5.712	EPSD	TCGA;ICGC	5.050	Down-regulation
TK_Src_SrcB_LCK_Y	P22681	CBL	P06239	LCK	Y371	Q367H	367	Missense	distal	-4	no	5.315	5.067	EPSD	TCGA;ICGC;COSMIC	5.050	Down-regulation
TK_Src_SrcB_LCK_Y	P22681	CBL	P06239	LCK	Y371	L370S	370	Missense	proximal	-1	no	5.315	3.730	EPSD	TCGA;ICGC	5.050	Loss
TK_Src_SrcB_LCK_Y	P22681	CBL	P06239	LCK	Y455	Y455N	455	Missense	central	0	yes	5.839	0.000	EPSD	TCGA	5.050	Loss
TK_Src_SrcB_LCK_Y	P22681	CBL	P06239	LCK	Y674	S675F	675	Missense	proximal	1	no	8.284	7.938	EPSD	TCGA;ICGC;COSMIC	5.050	Down-regulation
TK_Src_SrcB_LCK_Y	P22681	CBL	P06239	LCK	Y674	S669Y	669	Missense	distal	-5	no	8.284	7.589	EPSD	TCGA;ICGC	5.050	Down-regulation
TK_Src_SrcB_LCK_Y	P22681	CBL	P06239	LCK	Y674	A678D	678	Missense	distal	4	no	8.284	8.411	EPSD	TCGA;ICGC;COSMIC	5.050	Up-regulation
TK_Src_SrcB_LCK_Y	P22681	CBL	P06239	LCK	Y731	T730M	730	Missense	proximal	-1	no	8.083	8.280	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	5.050	Up-regulation
TK_Src_SrcB_LCK_Y	P22681	CBL	P06239	LCK	Y774	D772Y	772	Missense	proximal	-2	no	8.964	7.878	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	5.050	Down-regulation
TK_Src_SrcB_LCK_Y	P22681	CBL	P06239	LCK	Y774	D775V	775	Missense	proximal	1	no	8.964	7.765	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	5.050	Down-regulation
TK_Src_SrcB_LCK_Y	P60484	PTEN	P06239	LCK	Y68	Y65D	65	Missense	distal	-3	no	4.757	5.917	EPSD	TCGA;ICGC;COSMIC	5.050	Gain
TK_Src_SrcB_LCK_Y	P60484	PTEN	P06239	LCK	Y68	L70H	70	Missense	proximal	2	no	4.757	5.545	EPSD	TCGA;ICGC;COSMIC	5.050	Gain
TK_Src_SrcB_LCK_Y	P60484	PTEN	P06239	LCK	Y68	R74I	74	Missense	distal	6	no	4.757	5.125	EPSD	TCGA;ICGC;COSMIC	5.050	Gain
TK_Src_SrcB_LCK_Y	P60484	PTEN	P06239	LCK	Y155	D162N	162	Missense	distal	7	no	5.347	5.208	EPSD	TCGA;ICGC;COSMIC	5.050	Down-regulation
TK_Src_SrcB_LCK_Y	P60484	PTEN	P06239	LCK	Y155	R159K	159	Missense	distal	4	no	5.347	5.011	EPSD	TCGA;ICGC;COSMIC	5.050	Loss
TK_Src_SrcB_LCK_Y	P60484	PTEN	P06239	LCK	Y155	R159S	159	Missense	distal	4	no	5.347	5.141	EPSD	TCGA;ICGC;COSMIC;GDSC;CCLE	5.050	Down-regulation
TK_Src_SrcB_LCK_Y	P60484	PTEN	P06239	LCK	Y155	D153Y	153	Missense	proximal	-2	no	5.347	4.261	EPSD	TCGA;ICGC;COSMIC	5.050	Loss
TK_Src_SrcB_LCK_Y	P60484	PTEN	P06239	LCK	Y155	A148S	148	Missense	distal	-7	no	5.347	5.229	EPSD	TCGA;ICGC;COSMIC	5.050	Down-regulation
TK_Src_SrcB_LCK_Y	P60484	PTEN	P06239	LCK	Y155	R161S	161	Missense	distal	6	no	5.347	5.222	EPSD	TCGA;ICGC;COSMIC	5.050	Down-regulation
TK_Src_SrcB_LCK_Y	P60484	PTEN	P06239	LCK	Y155	F154L	154	Missense	proximal	-1	no	5.347	6.153	EPSD	TCGA;ICGC;COSMIC	5.050	Up-regulation
TK_Src_SrcB_LCK_Y	P60484	PTEN	P06239	LCK	Y155	L152P	152	Missense	distal	-3	no	5.347	5.581	EPSD	TCGA;ICGC;COSMIC;GDSC;CCLE	5.050	Up-regulation
TK_Src_SrcB_LCK_Y	P60484	PTEN	P06239	LCK	Y155	D153E	153	Missense	proximal	-2	no	5.347	5.098	EPSD	TCGA;ICGC;COSMIC	5.050	Down-regulation
TK_Src_SrcB_LCK_Y	P60484	PTEN	P06239	LCK	Y155	Y155C	155	Missense	central	0	yes	5.347	0.000	EPSD	TCGA;ICGC;COSMIC;GDSC;CCLE	5.050	Loss
TK_Src_SrcB_LCK_Y	P60484	PTEN	P06239	LCK	Y155	D162V	162	Missense	distal	7	no	5.347	5.048	EPSD	TCGA;ICGC;COSMIC	5.050	Loss
TK_Src_SrcB_LCK_Y	P60484	PTEN	P06239	LCK	Y176	R173C	173	Missense	distal	-3	no	5.532	4.017	EPSD	TCGA;ICGC;COSMIC;GDSC;CCLE	5.050	Loss
TK_Src_SrcB_LCK_Y	P60484	PTEN	P06239	LCK	Y176	R173H	173	Missense	distal	-3	no	5.532	4.416	EPSD	TCGA;ICGC;COSMIC;GDSC;CCLE	5.050	Loss
TK_Src_SrcB_LCK_Y	P60484	PTEN	P06239	LCK	Y176	S170N	170	Missense	distal	-6	no	5.532	5.318	EPSD	TCGA;ICGC;COSMIC	5.050	Down-regulation
TK_Src_SrcB_LCK_Y	P60484	PTEN	P06239	LCK	Y176	Y178C	178	Missense	proximal	2	no	5.532	4.540	EPSD	TCGA;ICGC;COSMIC	5.050	Loss
TK_Src_SrcB_LCK_Y	P60484	PTEN	P06239	LCK	Y176	S170G	170	Missense	distal	-6	no	5.532	5.057	EPSD	TCGA;ICGC;COSMIC	5.050	Down-regulation
TK_Src_SrcB_LCK_Y	P60484	PTEN	P06239	LCK	Y176	Q171K	171	Missense	distal	-5	no	5.532	5.497	EPSD	TCGA;ICGC;COSMIC	5.050	Down-regulation
TK_Src_SrcB_LCK_Y	P60484	PTEN	P06239	LCK	Y176	S170R	170	Missense	distal	-6	no	5.532	5.333	EPSD	TCGA;ICGC;COSMIC	5.050	Down-regulation
TK_Src_SrcB_LCK_Y	P60484	PTEN	P06239	LCK	Y176	S170I	170	Missense	distal	-6	no	5.532	4.551	EPSD	TCGA;ICGC;COSMIC	5.050	Loss
TK_Src_SrcB_LCK_Y	P60484	PTEN	P06239	LCK	Y176	Y177F	177	Missense	proximal	1	no	5.532	4.978	EPSD	TCGA;ICGC;COSMIC	5.050	Loss
TK_Src_SrcB_LCK_Y	P60484	PTEN	P06239	LCK	Y176	Q171R	171	Missense	distal	-5	no	5.532	5.463	EPSD	TCGA;ICGC;COSMIC	5.050	Down-regulation
TK_Src_SrcB_LCK_Y	P60484	PTEN	P06239	LCK	Y176	R173L	173	Missense	distal	-3	no	5.532	4.434	EPSD	TCGA;ICGC;COSMIC	5.050	Loss
TK_Src_SrcB_LCK_Y	P60484	PTEN	P06239	LCK	Y176	L181P	181	Missense	distal	5	no	5.532	5.417	EPSD	TCGA;ICGC;COSMIC	5.050	Down-regulation
TK_Src_SrcB_LCK_Y	P60484	PTEN	P06239	LCK	Y176	Q171E	171	Missense	distal	-5	no	5.532	6.157	EPSD	TCGA;ICGC;COSMIC	5.050	Up-regulation
TK_Src_SrcB_LCK_Y	P60484	PTEN	P06239	LCK	Y176	Y177D	177	Missense	proximal	1	no	5.532	6.349	EPSD	TCGA;ICGC;COSMIC	5.050	Up-regulation
TK_Src_SrcB_LCK_Y	P60484	PTEN	P06239	LCK	Y240	R233Q	233	Missense	distal	-7	no	6.412	6.272	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC;GDSC;CCLE	5.050	Down-regulation
TK_Src_SrcB_LCK_Y	P60484	PTEN	P06239	LCK	Y240	P246L	246	Missense	distal	6	no	6.412	6.522	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC;CCLE	5.050	Up-regulation
TK_Src_SrcB_LCK_Y	P60484	PTEN	P06239	LCK	Y240	M239R	239	Missense	proximal	-1	no	6.412	4.899	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	5.050	Loss
TK_Src_SrcB_LCK_Y	P60484	PTEN	P06239	LCK	Y240	M239V	239	Missense	proximal	-1	no	6.412	6.908	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	5.050	Up-regulation
TK_Src_SrcB_LCK_Y	P60484	PTEN	P06239	LCK	Y240	P246R	246	Missense	distal	6	no	6.412	6.100	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	5.050	Down-regulation
TK_Src_SrcB_LCK_Y	P60484	PTEN	P06239	LCK	Y240	L247F	247	Missense	distal	7	no	6.412	6.325	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	5.050	Down-regulation
TK_Src_SrcB_LCK_Y	P60484	PTEN	P06239	LCK	Y240	P246S	246	Missense	distal	6	no	6.412	5.975	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	5.050	Down-regulation
TK_Src_SrcB_LCK_Y	P60484	PTEN	P06239	LCK	Y240	Q245P	245	Missense	distal	5	no	6.412	6.465	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	5.050	Up-regulation
TK_Src_SrcB_LCK_Y	P60484	PTEN	P06239	LCK	Y240	Q245E	245	Missense	distal	5	no	6.412	6.338	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	5.050	Down-regulation
TK_Src_SrcB_LCK_Y	P60484	PTEN	P06239	LCK	Y240	F241S	241	Missense	proximal	1	no	6.412	6.758	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC;CCLE	5.050	Up-regulation
TK_Src_SrcB_LCK_Y	P60484	PTEN	P06239	LCK	Y315	D312N	312	Missense	distal	-3	no	6.389	5.413	PhosphoSitePlus;EPSD	TCGA;ICGC;COSMIC	5.050	Down-regulation
TK_Src_SrcB_LCK_Y	P60484	PTEN	P06239	LCK	Y315	K322E	322	Missense	distal	7	no	6.389	6.550	PhosphoSitePlus;EPSD	TCGA;ICGC;COSMIC	5.050	Up-regulation
TK_Src_SrcB_LCK_Y	P60484	PTEN	P06239	LCK	Y315	D310G	310	Missense	distal	-5	no	6.389	6.257	PhosphoSitePlus;EPSD	TCGA;ICGC;COSMIC;GDSC;CCLE	5.050	Down-regulation
TK_Src_SrcB_LCK_Y	P60484	PTEN	P06239	LCK	Y315	R308C	308	Missense	distal	-7	no	6.389	5.704	PhosphoSitePlus;EPSD	TCGA;ICGC;COSMIC	5.050	Down-regulation
TK_Src_SrcB_LCK_Y	P60484	PTEN	P06239	LCK	Y315	L320S	320	Missense	distal	5	no	6.389	6.193	PhosphoSitePlus;EPSD	TCGA;ICGC;COSMIC	5.050	Down-regulation
TK_Src_SrcB_LCK_Y	P60484	PTEN	P06239	LCK	Y377	E373K	373	Missense	distal	-4	no	6.975	6.172	EPSD	TCGA;ICGC	5.050	Down-regulation
TK_Src_SrcB_LCK_Y	P60484	PTEN	P06239	LCK	Y377	N372D	372	Missense	distal	-5	no	6.975	7.111	EPSD	TCGA;ICGC;COSMIC	5.050	Up-regulation
TK_Src_SrcB_LCK_Y	Q04759	PRKCQ	P06239	LCK	Y90	V87M	87	Missense	distal	-3	no	7.972	7.597	PhosphoSitePlus	TCGA;ICGC;COSMIC	5.050	Down-regulation
TK_Src_SrcB_LCK_Y	P05107	ITGB2	P06239	LCK	Y735	H728Y	728	Missense	distal	-7	no	5.684	5.558	PhosphoSitePlus	TCGA;ICGC;COSMIC	5.050	Down-regulation
TK_Src_SrcB_LCK_Y	P05107	ITGB2	P06239	LCK	Y735	R737H	737	Missense	proximal	2	no	5.684	6.235	PhosphoSitePlus	TCGA;ICGC;COSMIC	5.050	Up-regulation
TK_Src_SrcB_LCK_Y	P23743	DGKA	P06239	LCK	Y669	I668M	668	Missense	proximal	-1	no	5.148	4.266	EPSD	TCGA;ICGC;COSMIC	5.050	Loss
TK_Src_SrcB_LCK_Y	P24666	ACP1	P06239	LCK	Y132	E129Q	129	Missense	distal	-3	no	6.956	6.188	PhosphoSitePlus;EPSD	TCGA;ICGC;COSMIC	5.050	Down-regulation
TK_Src_SrcB_LCK_Y	P24666	ACP1	P06239	LCK	Y132	D130E	130	Missense	proximal	-2	no	6.956	6.707	PhosphoSitePlus;EPSD	TCGA;ICGC;COSMIC	5.050	Down-regulation
TK_Src_SrcB_LCK_Y	P24666	ACP1	P06239	LCK	Y133	E129Q	129	Missense	distal	-4	no	5.981	5.220	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	5.050	Down-regulation
TK_Src_SrcB_LCK_Y	P24666	ACP1	P06239	LCK	Y133	D130E	130	Missense	distal	-3	no	5.981	5.410	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	5.050	Down-regulation
TK_Src_SrcB_LCK_Y	P03372	ESR1	P06239	LCK	Y537	L541Q	541	Missense	distal	4	no	5.669	6.293	PhosphoSitePlus	TCGA;ICGC;COSMIC	5.050	Up-regulation
TK_Src_SrcB_LCK_Y	P03372	ESR1	P06239	LCK	Y537	Y537H	537	Missense	central	0	yes	5.669	0.000	PhosphoSitePlus	TCGA;ICGC;COSMIC	5.050	Loss
TK_Src_SrcB_LCK_Y	P03372	ESR1	P06239	LCK	Y537	V533M	533	Missense	distal	-4	no	5.669	5.897	PhosphoSitePlus	TCGA;ICGC;COSMIC	5.050	Up-regulation
TK_Src_SrcB_LCK_Y	P03372	ESR1	P06239	LCK	Y537	D538G	538	Missense	proximal	1	no	5.669	4.476	PhosphoSitePlus	TCGA;ICGC;COSMIC	5.050	Loss
TK_Src_SrcB_LCK_Y	P03372	ESR1	P06239	LCK	Y537	Y537N	537	Missense	central	0	yes	5.669	0.000	PhosphoSitePlus	TCGA;ICGC;COSMIC	5.050	Loss
TK_Src_SrcB_LCK_Y	P03372	ESR1	P06239	LCK	Y537	Y537S	537	Missense	central	0	yes	5.669	0.000	PhosphoSitePlus	TCGA;ICGC;COSMIC	5.050	Loss
TK_Src_SrcB_LCK_Y	Q96LC7	SIGLEC10	P06239	LCK	Y57	A56V	56	Missense	proximal	-1	no	3.639	5.212	EPSD	TCGA;ICGC	5.050	Gain
TK_Src_SrcB_LCK_Y	Q96LC7	SIGLEC10	P06239	LCK	Y597	N599D	599	Missense	proximal	2	no	6.695	6.440	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	5.050	Down-regulation
TK_Src_SrcB_LCK_Y	Q96LC7	SIGLEC10	P06239	LCK	Y667	E663Q	663	Missense	distal	-4	no	7.899	7.138	PhosphoSitePlus;EPSD	TCGA;COSMIC	5.050	Down-regulation
TK_Src_SrcB_LCK_Y	Q96LC7	SIGLEC10	P06239	LCK	Y667	E660K	660	Missense	distal	-7	no	7.899	7.479	PhosphoSitePlus;EPSD	TCGA;COSMIC	5.050	Down-regulation
TK_Src_SrcB_LCK_Y	Q96LC7	SIGLEC10	P06239	LCK	Y667	Q662L	662	Missense	distal	-5	no	7.899	8.020	PhosphoSitePlus;EPSD	TCGA;COSMIC	5.050	Up-regulation
TK_Src_SrcB_LCK_Y	P25963	NFKBIA	P06239	LCK	Y42	E41K	41	Missense	proximal	-1	no	8.519	5.664	PhosphoSitePlus	TCGA;ICGC	5.050	Down-regulation
TK_Src_SrcB_LCK_Y	P25963	NFKBIA	P06239	LCK	Y42	Y42C	42	Missense	central	0	yes	8.519	0.000	PhosphoSitePlus	TCGA;ICGC;COSMIC	5.050	Loss
TK_Src_SrcB_LCK_Y	O14543	SOCS3	P06239	LCK	Y204	V197I	197	Missense	distal	-7	no	5.655	5.554	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	5.050	Down-regulation
TK_Src_SrcB_LCK_Y	O14543	SOCS3	P06239	LCK	Y204	H200R	200	Missense	distal	-4	no	5.655	5.556	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	5.050	Down-regulation
TK_Src_SrcB_LCK_Y	O14543	SOCS3	P06239	LCK	Y204	P211L	211	Missense	distal	7	no	5.655	5.554	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	5.050	Down-regulation
TK_Src_SrcB_LCK_Y	Q13283	G3BP1	P06239	LCK	Y56	D53N	53	Missense	distal	-3	no	7.436	6.460	PhosphoSitePlus	TCGA;ICGC;COSMIC	5.050	Down-regulation
TK_Src_SrcB_LCK_Y	Q13283	G3BP1	P06239	LCK	Y174	D169E	169	Missense	distal	-5	no	6.195	6.589	EPSD	TCGA;ICGC;COSMIC	5.050	Up-regulation
TK_Src_SrcB_LCK_Y	Q08881	ITK	P06239	LCK	Y180	D181H	181	Missense	proximal	1	no	6.469	4.927	EPSD	TCGA;ICGC;COSMIC	5.050	Loss
TK_Src_SrcB_LCK_Y	Q08881	ITK	P06239	LCK	Y180	P187T	187	Missense	distal	7	no	6.469	6.339	EPSD	TCGA;ICGC;COSMIC;GDSC;CCLE	5.050	Down-regulation
TK_Src_SrcB_LCK_Y	Q08881	ITK	P06239	LCK	Y180	E173K	173	Missense	distal	-7	no	6.469	6.049	EPSD	TCGA;ICGC;COSMIC	5.050	Down-regulation
TK_Src_SrcB_LCK_Y	Q08881	ITK	P06239	LCK	Y180	V175M	175	Missense	distal	-5	no	6.469	7.107	EPSD	TCGA;ICGC	5.050	Up-regulation
TK_Src_SrcB_LCK_Y	Q08881	ITK	P06239	LCK	Y512	T516K	516	Missense	distal	4	no	7.871	8.100	PhosphoSitePlus	TCGA;ICGC;COSMIC	5.050	Up-regulation
TK_Src_SrcB_LCK_Y	Q08881	ITK	P06239	LCK	Y512	L508Q	508	Missense	distal	-4	no	7.871	8.584	PhosphoSitePlus	TCGA;ICGC;COSMIC	5.050	Up-regulation
TK_Src_SrcB_LCK_Y	P15311	EZR	P06239	LCK	Y116	G109R	109	Missense	distal	-7	no	5.031	5.335	EPSD	TCGA;ICGC;COSMIC	5.050	Gain
TK_Src_SrcB_LCK_Y	P15311	EZR	P06239	LCK	Y146	S148R	148	Missense	proximal	2	no	6.198	5.344	PhosphoSitePlus	TCGA;ICGC	5.050	Down-regulation
TK_Src_SrcB_LCK_Y	P15311	EZR	P06239	LCK	Y424	K427N	427	Missense	distal	3	no	6.018	5.607	EPSD	TCGA;ICGC;COSMIC	5.050	Down-regulation
TK_Src_SrcB_LCK_Y	P15311	EZR	P06239	LCK	Y424	T425I	425	Missense	proximal	1	no	6.018	5.199	EPSD	TCGA;ICGC;COSMIC	5.050	Down-regulation
TK_Src_SrcB_LCK_Y	P15311	EZR	P06239	LCK	Y424	A426V	426	Missense	proximal	2	no	6.018	4.718	EPSD	TCGA;ICGC;COSMIC	5.050	Loss
TK_Src_SrcB_LCK_Y	P15311	EZR	P06239	LCK	Y478	P480Q	480	Missense	proximal	2	no	6.042	5.288	EPSD	TCGA;ICGC;COSMIC	5.050	Down-regulation
TK_Src_SrcB_LCK_Y	P42768	WAS	P06239	LCK	Y54	A56V	56	Missense	proximal	2	no	6.238	4.937	EPSD	TCGA;ICGC;COSMIC	5.050	Loss
TK_Src_SrcB_LCK_Y	P42768	WAS	P06239	LCK	Y291	D292N	292	Missense	proximal	1	no	9.097	8.506	PhosphoSitePlus	TCGA;ICGC;COSMIC	5.050	Down-regulation
TK_Src_SrcB_LCK_Y	P42768	WAS	P06239	LCK	Y291	F293L	293	Missense	proximal	2	no	9.097	8.841	PhosphoSitePlus	TCGA;ICGC;COSMIC	5.050	Down-regulation
TK_Src_SrcB_LCK_Y	Q9UHD2	TBK1	P06239	LCK	Y153	D157E	157	Missense	distal	4	no	5.423	5.676	EPSD	TCGA;ICGC;COSMIC	5.050	Up-regulation
TK_Src_SrcB_LCK_Y	Q9UHD2	TBK1	P06239	LCK	Y153	F158C	158	Missense	distal	5	no	5.423	5.568	EPSD	TCGA;ICGC;COSMIC	5.050	Up-regulation
TK_Src_SrcB_LCK_Y	Q9UHD2	TBK1	P06239	LCK	Y185	D183Y	183	Missense	proximal	-2	no	5.617	4.531	EPSD	TCGA;ICGC;COSMIC	5.050	Loss
TK_Src_SrcB_LCK_Y	Q9UHD2	TBK1	P06239	LCK	Y354	E355K	355	Missense	proximal	1	no	6.710	5.761	PhosphoSitePlus;EPSD	TCGA;ICGC;COSMIC	5.050	Down-regulation
TK_Src_SrcB_LCK_Y	Q9UN19	DAPP1	P06239	LCK	Y139	S141F	141	Missense	proximal	2	no	9.733	8.897	PhosphoSitePlus	TCGA;ICGC;COSMIC	5.050	Down-regulation
TK_Src_SrcB_LCK_Y	Q9UN19	DAPP1	P06239	LCK	Y139	V144A	144	Missense	distal	5	no	9.733	9.588	PhosphoSitePlus	TCGA;ICGC;COSMIC	5.050	Down-regulation
TK_Src_SrcB_LCK_Y	Q9UN19	DAPP1	P06239	LCK	Y139	E135K	135	Missense	distal	-4	no	9.733	8.930	PhosphoSitePlus	TCGA;ICGC;COSMIC	5.050	Down-regulation
TK_Src_SrcB_LCK_Y	Q9UN19	DAPP1	P06239	LCK	Y139	S141Y	141	Missense	proximal	2	no	9.733	8.809	PhosphoSitePlus	TCGA;ICGC;COSMIC	5.050	Down-regulation
TK_Src_SrcB_LCK_Y	Q9BZS1	FOXP3	P06239	LCK	Y342	R337Q	337	Missense	distal	-5	no	6.412	6.481	PhosphoSitePlus	TCGA;COSMIC	5.050	Up-regulation
TK_Src_SrcB_LCK_Y	Q9BZS1	FOXP3	P06239	LCK	Y342	R347H	347	Missense	distal	5	no	6.412	6.441	PhosphoSitePlus	TCGA;COSMIC	5.050	Up-regulation
TK_Ret_RET_Y	P40763	STAT3	Q15300	RET	Y539	P535L	535	Missense	distal	-4	no	30.476	24.702	EPSD	TCGA;ICGC	28.094	Loss
TK_Ret_RET_Y	P40763	STAT3	Q15300	RET	Y539	S540L	540	Missense	proximal	1	no	30.476	29.631	EPSD	TCGA;ICGC;COSMIC	28.094	Down-regulation
TK_Ret_RET_Y	P40763	STAT3	Q15300	RET	Y686	Y686D	686	Missense	central	0	yes	28.945	0.000	EPSD	TCGA;ICGC	28.094	Loss
TK_Ret_RET_Y	P40763	STAT3	Q15300	RET	Y686	A682T	682	Missense	distal	-4	no	28.945	27.465	EPSD	TCGA;ICGC	28.094	Loss
TK_Ret_RET_Y	P40763	STAT3	Q15300	RET	Y686	K679N	679	Missense	distal	-7	no	28.945	28.257	EPSD	TCGA;ICGC	28.094	Down-regulation
Other_KIS_UHMK1_ST	P46527	CDKN1B	Q8TAS1	UHMK1	S10	S7C	7	Missense	distal	-3	no	4.134	4.119	PhosphoSitePlus	TCGA;ICGC;COSMIC	1.522	Down-regulation
Other_KIS_UHMK1_ST	P46527	CDKN1B	Q8TAS1	UHMK1	S10	G9W	9	Missense	proximal	-1	no	4.134	3.863	PhosphoSitePlus	TCGA;ICGC;COSMIC	1.522	Down-regulation
Other_KIS_UHMK1_ST	P46527	CDKN1B	Q8TAS1	UHMK1	S112	A116S	116	Missense	distal	4	no	1.641	1.733	EPSD	TCGA;ICGC;COSMIC	1.522	Up-regulation
Other_KIS_UHMK1_ST	P16949	STMN1	Q8TAS1	UHMK1	S25	S31Y	31	Missense	distal	6	no	2.925	2.957	EPSD	TCGA;COSMIC	1.522	Up-regulation
Other_KIS_UHMK1_ST	P16949	STMN1	Q8TAS1	UHMK1	S25	S28P	28	Missense	distal	3	no	2.925	2.892	EPSD	TCGA;ICGC	1.522	Down-regulation
Other_KIS_UHMK1_ST	P16949	STMN1	Q8TAS1	UHMK1	S25	K29I	29	Missense	distal	4	no	2.925	2.663	EPSD	TCGA;ICGC;COSMIC	1.522	Down-regulation
Other_KIS_UHMK1_ST	P16949	STMN1	Q8TAS1	UHMK1	S38	S31Y	31	Missense	distal	-7	no	4.392	4.135	PhosphoSitePlus	TCGA;COSMIC	1.522	Down-regulation
Other_KIS_UHMK1_ST	P16949	STMN1	Q8TAS1	UHMK1	S38	P39S	39	Missense	proximal	1	no	4.392	2.896	PhosphoSitePlus	TCGA;ICGC;COSMIC	1.522	Down-regulation
Other_IKK_IKBKE_ST	Q96FA3	PELI1	Q14164	IKBKE	S76	S78L	78	Missense	proximal	2	no	95.218	88.970	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	71.554	Down-regulation
Other_IKK_IKBKE_ST	Q96FA3	PELI1	Q14164	IKBKE	S76	Y79H	79	Missense	distal	3	no	95.218	94.624	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	71.554	Down-regulation
Other_IKK_IKBKE_ST	Q96FA3	PELI1	Q14164	IKBKE	S76	S70G	70	Missense	distal	-6	no	95.218	96.374	EPSD;PhosphoSitePlus	TCGA;ICGC	71.554	Up-regulation
Other_IKK_IKBKE_ST	Q96FA3	PELI1	Q14164	IKBKE	T80	V87L	87	Missense	distal	7	no	95.218	95.776	PhosphoSitePlus;EPSD	TCGA;ICGC;COSMIC	71.554	Up-regulation
Other_IKK_IKBKE_ST	Q96FA3	PELI1	Q14164	IKBKE	T80	S78L	78	Missense	proximal	-2	no	95.218	101.848	PhosphoSitePlus;EPSD	TCGA;ICGC;COSMIC	71.554	Up-regulation
Other_IKK_IKBKE_ST	Q96FA3	PELI1	Q14164	IKBKE	T80	Y79H	79	Missense	proximal	-1	no	95.218	92.849	PhosphoSitePlus;EPSD	TCGA;ICGC;COSMIC	71.554	Down-regulation
Other_IKK_IKBKE_ST	Q96FA3	PELI1	Q14164	IKBKE	T80	Q85H	85	Missense	distal	5	no	95.218	94.171	PhosphoSitePlus;EPSD	TCGA;ICGC;COSMIC	71.554	Down-regulation
Other_IKK_IKBKE_ST	Q96FA3	PELI1	Q14164	IKBKE	T288	P283H	283	Missense	distal	-5	no	97.303	95.062	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	71.554	Down-regulation
Other_IKK_IKBKE_ST	Q96FA3	PELI1	Q14164	IKBKE	S293	V299I	299	Missense	distal	6	no	100.743	92.111	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC;CCLE	71.554	Down-regulation
Other_IKK_IKBKE_ST	P25963	NFKBIA	Q14164	IKBKE	S32	D31N	31	Missense	proximal	-1	no	107.210	106.005	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	71.554	Down-regulation
Other_IKK_IKBKE_ST	P25963	NFKBIA	Q14164	IKBKE	S32	D27H	27	Missense	distal	-5	no	107.210	101.953	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	71.554	Down-regulation
Other_IKK_IKBKE_ST	P25963	NFKBIA	Q14164	IKBKE	S36	E41K	41	Missense	distal	5	no	98.765	100.091	PhosphoSitePlus;EPSD	TCGA;ICGC	71.554	Up-regulation
Other_IKK_IKBKE_ST	P25963	NFKBIA	Q14164	IKBKE	S36	D31N	31	Missense	distal	-5	no	98.765	99.551	PhosphoSitePlus;EPSD	TCGA;ICGC;COSMIC	71.554	Up-regulation
Other_IKK_IKBKE_ST	P25963	NFKBIA	Q14164	IKBKE	S36	Y42C	42	Missense	distal	6	no	98.765	94.403	PhosphoSitePlus;EPSD	TCGA;ICGC;COSMIC	71.554	Down-regulation
Other_IKK_IKBKE_ST	P25963	NFKBIA	Q14164	IKBKE	S174	S174P	174	Missense	central	0	yes	82.680	0.000	EPSD	TCGA;COSMIC	71.554	Loss
Other_IKK_IKBKE_ST	Q14653	IRF3	Q14164	IKBKE	S175	P170S	170	Missense	distal	-5	no	78.406	74.693	EPSD	TCGA;COSMIC;CCLE	71.554	Down-regulation
Other_IKK_IKBKE_ST	P10914	IRF1	Q14164	IKBKE	S215	L209V	209	Missense	distal	-6	no	94.464	94.009	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	71.554	Down-regulation
Other_IKK_IKBKE_ST	P10914	IRF1	Q14164	IKBKE	S219	T225I	225	Missense	distal	6	no	99.613	86.363	PhosphoSitePlus;EPSD	TCGA;ICGC;COSMIC	71.554	Down-regulation
Other_IKK_IKBKE_ST	P10914	IRF1	Q14164	IKBKE	S219	A223P	223	Missense	distal	4	no	99.613	95.691	PhosphoSitePlus;EPSD	TCGA;ICGC;COSMIC	71.554	Down-regulation
Other_IKK_IKBKE_ST	P10914	IRF1	Q14164	IKBKE	S221	T225I	225	Missense	distal	4	no	95.211	65.150	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	71.554	Loss
Other_IKK_IKBKE_ST	P10914	IRF1	Q14164	IKBKE	S221	A223P	223	Missense	proximal	2	no	95.211	94.843	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	71.554	Down-regulation
Other_IKK_IKBKE_ST	O95786	DDX58	Q14164	IKBKE	S854	K849E	849	Missense	distal	-5	no	67.992	74.646	EPSD	TCGA;COSMIC	71.554	Gain
Other_IKK_IKBKE_ST	O95786	DDX58	Q14164	IKBKE	S855	A860T	860	Missense	distal	5	no	99.185	101.411	PhosphoSitePlus	TCGA;COSMIC	71.554	Up-regulation
Other_IKK_IKBKE_ST	O95786	DDX58	Q14164	IKBKE	S855	K849E	849	Missense	distal	-6	no	99.185	99.687	PhosphoSitePlus	TCGA;COSMIC	71.554	Up-regulation
Other_IKK_IKBKE_ST	O95786	DDX58	Q14164	IKBKE	S855	R859K	859	Missense	distal	4	no	99.185	105.782	PhosphoSitePlus	TCGA;COSMIC	71.554	Up-regulation
Other_IKK_IKBKE_ST	P03372	ESR1	Q14164	IKBKE	T7	A9T	9	Missense	proximal	2	no	70.825	74.760	EPSD	TCGA;COSMIC	71.554	Gain
Other_IKK_IKBKE_ST	P03372	ESR1	Q14164	IKBKE	T7	A13T	13	Missense	distal	6	no	70.825	72.654	EPSD	TCGA;ICGC;COSMIC	71.554	Gain
Other_IKK_IKBKE_ST	P03372	ESR1	Q14164	IKBKE	S46	Y52H	52	Missense	distal	6	no	76.917	71.723	EPSD	TCGA;ICGC;COSMIC	71.554	Down-regulation
Other_IKK_IKBKE_ST	P03372	ESR1	Q14164	IKBKE	S46	E41D	41	Missense	distal	-5	no	76.917	78.278	EPSD	TCGA;ICGC;COSMIC	71.554	Up-regulation
Other_IKK_IKBKE_ST	P03372	ESR1	Q14164	IKBKE	S46	G40V	40	Missense	distal	-6	no	76.917	77.169	EPSD	TCGA;ICGC;COSMIC	71.554	Up-regulation
Other_IKK_IKBKE_ST	P03372	ESR1	Q14164	IKBKE	S167	A166S	166	Missense	proximal	-1	no	96.639	98.840	PhosphoSitePlus	TCGA;ICGC;COSMIC	71.554	Up-regulation
Other_IKK_IKBKE_ST	P03372	ESR1	Q14164	IKBKE	S167	K171M	171	Missense	distal	4	no	96.639	98.773	PhosphoSitePlus	TCGA;ICGC;COSMIC	71.554	Up-regulation
Other_IKK_IKBKE_ST	P03372	ESR1	Q14164	IKBKE	S305	A307S	307	Missense	proximal	2	no	71.296	75.572	EPSD	TCGA;ICGC;COSMIC	71.554	Gain
Other_IKK_IKBKE_ST	P31749	AKT1	Q14164	IKBKE	S122	E116K	116	Missense	distal	-6	no	80.079	79.577	EPSD	TCGA;ICGC;COSMIC	71.554	Down-regulation
Other_IKK_IKBKE_ST	P31749	AKT1	Q14164	IKBKE	S122	R121W	121	Missense	proximal	-1	no	80.079	70.541	EPSD	TCGA;ICGC;COSMIC	71.554	Loss
Other_IKK_IKBKE_ST	P31749	AKT1	Q14164	IKBKE	T308	G311D	311	Missense	distal	3	no	94.602	95.389	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC;GDSC;CCLE	71.554	Up-regulation
Other_IKK_IKBKE_ST	P31749	AKT1	Q14164	IKBKE	S378	L384F	384	Missense	distal	6	no	77.927	76.987	EPSD	TCGA;COSMIC	71.554	Down-regulation
Other_IKK_IKBKE_ST	P31749	AKT1	Q14164	IKBKE	S473	S475L	475	Missense	proximal	2	no	82.406	76.158	PhosphoSitePlus;EPSD	TCGA;ICGC;COSMIC	71.554	Down-regulation
Other_IKK_IKBKE_ST	O14519	CDK2AP1	Q14164	IKBKE	S28	S26F	26	Missense	proximal	-2	no	79.825	88.431	EPSD	TCGA;ICGC;COSMIC	71.554	Up-regulation
Other_IKK_IKBKE_ST	O14519	CDK2AP1	Q14164	IKBKE	S28	S33L	33	Missense	distal	5	no	79.825	79.051	EPSD	TCGA;COSMIC	71.554	Down-regulation
Other_IKK_IKBKE_ST	O14519	CDK2AP1	Q14164	IKBKE	T31	S26F	26	Missense	distal	-5	no	67.289	73.620	EPSD	TCGA;ICGC;COSMIC	71.554	Gain
Other_IKK_IKBKE_ST	O14519	CDK2AP1	Q14164	IKBKE	S32	S33L	33	Missense	proximal	1	no	66.699	73.729	EPSD	TCGA;COSMIC	71.554	Gain
Other_IKK_IKBKE_ST	O14519	CDK2AP1	Q14164	IKBKE	S46	P45L	45	Missense	proximal	-1	no	100.574	97.618	PhosphoSitePlus	TCGA;COSMIC	71.554	Down-regulation
Other_IKK_IKBKE_ST	O14519	CDK2AP1	Q14164	IKBKE	S46	S40N	40	Missense	distal	-6	no	100.574	101.735	PhosphoSitePlus	TCGA;GDSC;CCLE	71.554	Up-regulation
Other_IKK_IKBKE_ST	P98170	XIAP	Q14164	IKBKE	S5	S9Y	9	Missense	distal	4	no	96.387	85.083	EPSD	TCGA;ICGC;COSMIC	71.554	Down-regulation
Other_IKK_IKBKE_ST	P98170	XIAP	Q14164	IKBKE	S5	K10N	10	Missense	distal	5	no	96.387	95.320	EPSD	TCGA;ICGC	71.554	Down-regulation
Other_IKK_IKBKE_ST	P98170	XIAP	Q14164	IKBKE	S38	A34S	34	Missense	distal	-4	no	76.505	79.209	EPSD	TCGA;ICGC;COSMIC	71.554	Up-regulation
Other_IKK_IKBKE_ST	P98170	XIAP	Q14164	IKBKE	S38	F33L	33	Missense	distal	-5	no	76.505	66.207	EPSD	TCGA;ICGC;COSMIC	71.554	Loss
Other_IKK_IKBKE_ST	P98170	XIAP	Q14164	IKBKE	S38	T32N	32	Missense	distal	-6	no	76.505	77.113	EPSD	TCGA	71.554	Up-regulation
Other_IKK_IKBKE_ST	P98170	XIAP	Q14164	IKBKE	S40	A34S	34	Missense	distal	-6	no	76.542	74.563	EPSD	TCGA;ICGC;COSMIC	71.554	Down-regulation
Other_IKK_IKBKE_ST	P98170	XIAP	Q14164	IKBKE	S40	F33L	33	Missense	distal	-7	no	76.542	76.026	EPSD	TCGA;ICGC;COSMIC	71.554	Down-regulation
Other_IKK_IKBKE_ST	P98170	XIAP	Q14164	IKBKE	S347	L344S	344	Missense	distal	-3	no	77.785	79.076	EPSD	TCGA;ICGC	71.554	Up-regulation
Other_IKK_IKBKE_ST	P46937	YAP1	Q14164	IKBKE	S103	R106Q	106	Missense	distal	3	no	77.490	75.859	EPSD	TCGA;ICGC;COSMIC;CCLE	71.554	Down-regulation
Other_IKK_IKBKE_ST	P46937	YAP1	Q14164	IKBKE	S103	S109N	109	Missense	distal	6	no	77.490	71.077	EPSD	TCGA;ICGC;COSMIC	71.554	Loss
Other_IKK_IKBKE_ST	P46937	YAP1	Q14164	IKBKE	S149	T154A	154	Missense	distal	5	no	78.232	76.006	EPSD	TCGA;ICGC;COSMIC	71.554	Down-regulation
Other_IKK_IKBKE_ST	P46937	YAP1	Q14164	IKBKE	S164	Q158H	158	Missense	distal	-6	no	81.450	83.719	EPSD	TCGA;ICGC;COSMIC	71.554	Up-regulation
Other_IKK_IKBKE_ST	P46937	YAP1	Q14164	IKBKE	S164	I167M	167	Missense	distal	3	no	81.450	81.864	EPSD	TCGA;ICGC	71.554	Up-regulation
Other_IKK_IKBKE_ST	P46937	YAP1	Q14164	IKBKE	T216	A214T	214	Missense	proximal	-2	no	74.560	77.886	EPSD	TCGA;ICGC	71.554	Up-regulation
Other_IKK_IKBKE_ST	P46937	YAP1	Q14164	IKBKE	S350	Q344K	344	Missense	distal	-6	no	76.931	76.978	EPSD	TCGA;ICGC;COSMIC	71.554	Up-regulation
Other_IKK_IKBKE_ST	P46937	YAP1	Q14164	IKBKE	S406	P413Q	413	Missense	distal	7	no	75.332	74.838	EPSD	TCGA;ICGC;COSMIC	71.554	Down-regulation
Other_IKK_IKBKE_ST	P46937	YAP1	Q14164	IKBKE	S419	E422D	422	Missense	distal	3	no	104.296	103.243	PhosphoSitePlus	TCGA;COSMIC	71.554	Down-regulation
Other_IKK_IKBKE_ST	P46937	YAP1	Q14164	IKBKE	S419	P413Q	413	Missense	distal	-6	no	104.296	103.897	PhosphoSitePlus	TCGA;ICGC;COSMIC	71.554	Down-regulation
Other_IKK_IKBKE_ST	O00571	DDX3X	Q14164	IKBKE	S24	D25N	25	Missense	proximal	1	no	66.272	77.325	EPSD	TCGA;COSMIC	71.554	Gain
Other_IKK_IKBKE_ST	O00571	DDX3X	Q14164	IKBKE	S86	G80R	80	Missense	distal	-6	no	74.019	71.934	EPSD	TCGA;COSMIC	71.554	Down-regulation
Other_IKK_IKBKE_ST	O00571	DDX3X	Q14164	IKBKE	S102	R99H	99	Missense	distal	-3	no	98.722	97.730	PhosphoSitePlus	TCGA;COSMIC	71.554	Down-regulation
Other_IKK_IKBKE_ST	O00571	DDX3X	Q14164	IKBKE	S102	R99C	99	Missense	distal	-3	no	98.722	97.317	PhosphoSitePlus	TCGA;COSMIC	71.554	Down-regulation
Other_IKK_IKBKE_ST	O00571	DDX3X	Q14164	IKBKE	S102	R101W	101	Missense	proximal	-1	no	98.722	89.184	PhosphoSitePlus	TCGA;COSMIC	71.554	Down-regulation
Other_IKK_IKBKE_ST	O00571	DDX3X	Q14164	IKBKE	S102	G108D	108	Missense	distal	6	no	98.722	98.528	PhosphoSitePlus	TCGA;COSMIC	71.554	Down-regulation
Other_IKK_IKBKE_ST	O00571	DDX3X	Q14164	IKBKE	S114	R121H	121	Missense	distal	7	no	77.913	80.044	EPSD	TCGA;COSMIC	71.554	Up-regulation
Other_IKK_IKBKE_ST	O00571	DDX3X	Q14164	IKBKE	S114	R113G	113	Missense	proximal	-1	no	77.913	71.370	EPSD	TCGA	71.554	Loss
Other_IKK_IKBKE_ST	O00571	DDX3X	Q14164	IKBKE	S114	R110C	110	Missense	distal	-4	no	77.913	71.297	EPSD	TCGA;COSMIC	71.554	Loss
Other_IKK_IKBKE_ST	O00571	DDX3X	Q14164	IKBKE	S114	G108D	108	Missense	distal	-6	no	77.913	78.649	EPSD	TCGA;COSMIC	71.554	Up-regulation
Other_IKK_IKBKE_ST	O00571	DDX3X	Q14164	IKBKE	S269	R263H	263	Missense	distal	-6	no	79.021	82.533	EPSD	TCGA;ICGC;COSMIC	71.554	Up-regulation
Other_IKK_IKBKE_ST	O00571	DDX3X	Q14164	IKBKE	S269	R262C	262	Missense	distal	-7	no	79.021	81.513	EPSD	TCGA;ICGC;COSMIC	71.554	Up-regulation
Other_IKK_IKBKE_ST	O00571	DDX3X	Q14164	IKBKE	S269	T275M	275	Missense	distal	6	no	79.021	78.431	EPSD	TCGA;ICGC;COSMIC	71.554	Down-regulation
Other_IKK_IKBKE_ST	O00571	DDX3X	Q14164	IKBKE	S269	P267T	267	Missense	proximal	-2	no	79.021	81.869	EPSD	TCGA;ICGC;COSMIC	71.554	Up-regulation
Other_IKK_IKBKE_ST	O00571	DDX3X	Q14164	IKBKE	S269	R262H	262	Missense	distal	-7	no	79.021	80.676	EPSD	TCGA;ICGC;COSMIC;GDSC;CCLE	71.554	Up-regulation
Other_IKK_IKBKE_ST	O00571	DDX3X	Q14164	IKBKE	S269	P267S	267	Missense	proximal	-2	no	79.021	85.151	EPSD	TCGA;ICGC;COSMIC	71.554	Up-regulation
Other_IKK_IKBKE_ST	O00571	DDX3X	Q14164	IKBKE	S269	R263C	263	Missense	distal	-6	no	79.021	82.400	EPSD	TCGA;ICGC;COSMIC	71.554	Up-regulation
Other_IKK_IKBKE_ST	O00571	DDX3X	Q14164	IKBKE	T438	D441H	441	Missense	distal	3	no	74.598	72.637	EPSD	TCGA;ICGC;COSMIC	71.554	Down-regulation
Other_IKK_IKBKE_ST	O00571	DDX3X	Q14164	IKBKE	T438	G439C	439	Missense	proximal	1	no	74.598	53.683	EPSD	TCGA;ICGC	71.554	Loss
Other_IKK_IKBKE_ST	O00571	DDX3X	Q14164	IKBKE	S489	P493S	493	Missense	distal	4	no	71.722	79.553	EPSD	TCGA;ICGC;COSMIC	71.554	Up-regulation
Other_IKK_IKBKE_ST	O00571	DDX3X	Q14164	IKBKE	S492	P493S	493	Missense	proximal	1	no	75.194	71.546	EPSD	TCGA;ICGC;COSMIC	71.554	Loss
Other_IKK_IKBKE_ST	O00571	DDX3X	Q14164	IKBKE	S520	I514V	514	Missense	distal	-6	no	83.612	80.934	EPSD	TCGA;ICGC;COSMIC	71.554	Down-regulation
Other_IKK_IKBKE_ST	O00571	DDX3X	Q14164	IKBKE	S520	D521H	521	Missense	proximal	1	no	83.612	94.229	EPSD	TCGA;ICGC;COSMIC	71.554	Up-regulation
Other_IKK_IKBKE_ST	O00571	DDX3X	Q14164	IKBKE	S520	P519L	519	Missense	proximal	-1	no	83.612	80.656	EPSD	TCGA;ICGC;COSMIC	71.554	Down-regulation
Other_IKK_IKBKE_ST	O00571	DDX3X	Q14164	IKBKE	S610	R603Q	603	Missense	distal	-7	no	72.289	73.342	EPSD	TCGA;ICGC;COSMIC;CCLE	71.554	Up-regulation
Other_IKK_IKBKE_ST	O00571	DDX3X	Q14164	IKBKE	S615	A618T	618	Missense	distal	3	no	70.184	72.800	EPSD	TCGA;ICGC;COSMIC;CCLE	71.554	Gain
Other_IKK_IKBKE_ST	O00571	DDX3X	Q14164	IKBKE	S619	G625R	625	Missense	distal	6	no	80.761	77.430	EPSD	TCGA;ICGC;COSMIC	71.554	Down-regulation
Other_IKK_IKBKE_ST	O00571	DDX3X	Q14164	IKBKE	S619	A618T	618	Missense	proximal	-1	no	80.761	83.990	EPSD	TCGA;ICGC;COSMIC;CCLE	71.554	Up-regulation
Other_IKK_IKBKE_ST	O00571	DDX3X	Q14164	IKBKE	S620	G625R	625	Missense	distal	5	no	73.395	74.972	EPSD	TCGA;ICGC;COSMIC	71.554	Up-regulation
Other_IKK_IKBKE_ST	O00571	DDX3X	Q14164	IKBKE	S620	A618T	618	Missense	proximal	-2	no	73.395	76.720	EPSD	TCGA;ICGC;COSMIC;CCLE	71.554	Up-regulation
Other_IKK_IKBKE_ST	O00571	DDX3X	Q14164	IKBKE	S630	R632K	632	Missense	proximal	2	no	79.620	78.885	EPSD	TCGA;ICGC;COSMIC	71.554	Down-regulation
Other_IKK_IKBKE_ST	O00571	DDX3X	Q14164	IKBKE	S630	G636E	636	Missense	distal	6	no	79.620	77.086	EPSD	TCGA;ICGC;COSMIC	71.554	Down-regulation
Other_IKK_IKBKE_ST	O00571	DDX3X	Q14164	IKBKE	S630	G625R	625	Missense	distal	-5	no	79.620	81.172	EPSD	TCGA;ICGC;COSMIC	71.554	Up-regulation
Other_IKK_IKBKE_ST	O00571	DDX3X	Q14164	IKBKE	S631	R632K	632	Missense	proximal	1	no	78.417	81.736	EPSD	TCGA;ICGC;COSMIC	71.554	Up-regulation
Other_IKK_IKBKE_ST	O00571	DDX3X	Q14164	IKBKE	S631	G636E	636	Missense	distal	5	no	78.417	79.364	EPSD	TCGA;ICGC;COSMIC	71.554	Up-regulation
Other_IKK_IKBKE_ST	O00571	DDX3X	Q14164	IKBKE	S631	G625R	625	Missense	distal	-6	no	78.417	76.332	EPSD	TCGA;ICGC;COSMIC	71.554	Down-regulation
Other_IKK_IKBKE_ST	Q04206	RELA	Q14164	IKBKE	S45	E39K	39	Missense	distal	-6	no	73.237	72.736	EPSD	TCGA;ICGC;COSMIC	71.554	Down-regulation
Other_IKK_IKBKE_ST	Q04206	RELA	Q14164	IKBKE	S45	E49K	49	Missense	distal	4	no	73.237	79.712	EPSD	TCGA;ICGC;COSMIC	71.554	Up-regulation
Other_IKK_IKBKE_ST	Q04206	RELA	Q14164	IKBKE	S45	G44V	44	Missense	proximal	-1	no	73.237	80.150	EPSD	TCGA;ICGC;COSMIC	71.554	Up-regulation
Other_IKK_IKBKE_ST	Q04206	RELA	Q14164	IKBKE	T254	P256S	256	Missense	proximal	2	no	76.906	81.550	EPSD	TCGA;ICGC;COSMIC	71.554	Up-regulation
Other_IKK_IKBKE_ST	Q04206	RELA	Q14164	IKBKE	T254	P256L	256	Missense	proximal	2	no	76.906	75.303	EPSD	TCGA;ICGC;COSMIC	71.554	Down-regulation
Other_IKK_IKBKE_ST	Q04206	RELA	Q14164	IKBKE	T254	A258V	258	Missense	distal	4	no	76.906	77.349	EPSD	TCGA;ICGC;COSMIC	71.554	Up-regulation
Other_IKK_IKBKE_ST	Q04206	RELA	Q14164	IKBKE	T254	R253W	253	Missense	proximal	-1	no	76.906	67.368	EPSD	TCGA;ICGC;COSMIC	71.554	Loss
Other_IKK_IKBKE_ST	Q04206	RELA	Q14164	IKBKE	S311	F309L	309	Missense	proximal	-2	no	80.995	79.019	EPSD	TCGA;ICGC;COSMIC	71.554	Down-regulation
Other_IKK_IKBKE_ST	Q04206	RELA	Q14164	IKBKE	S311	E307K	307	Missense	distal	-4	no	80.995	78.979	EPSD	TCGA;ICGC;COSMIC	71.554	Down-regulation
Other_IKK_IKBKE_ST	Q04206	RELA	Q14164	IKBKE	S311	T308A	308	Missense	distal	-3	no	80.995	77.439	EPSD	TCGA;ICGC;COSMIC	71.554	Down-regulation
Other_IKK_IKBKE_ST	Q04206	RELA	Q14164	IKBKE	S468	V469I	469	Missense	proximal	1	no	95.113	97.394	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	71.554	Up-regulation
Other_IKK_IKBKE_ST	Q04206	RELA	Q14164	IKBKE	S536	S529L	529	Missense	distal	-7	no	85.327	85.754	PhosphoSitePlus;EPSD	TCGA;ICGC;COSMIC;GDSC;CCLE	71.554	Up-regulation
Other_IKK_IKBKE_ST	Q14164	IKBKE	Q14164	IKBKE	S172	V171F	171	Missense	proximal	-1	no	100.814	94.387	EPSD	TCGA;ICGC;COSMIC	71.554	Down-regulation
Other_IKK_IKBKE_ST	Q14164	IKBKE	Q14164	IKBKE	S519	R525W	525	Missense	distal	6	no	80.018	76.527	EPSD	TCGA;ICGC;COSMIC	71.554	Down-regulation
Other_IKK_IKBKE_ST	Q14164	IKBKE	Q14164	IKBKE	S522	K529N	529	Missense	distal	7	no	90.537	89.995	EPSD	TCGA;ICGC;COSMIC	71.554	Down-regulation
Other_IKK_IKBKE_ST	Q14164	IKBKE	Q14164	IKBKE	S522	R525W	525	Missense	distal	3	no	90.537	85.774	EPSD	TCGA;ICGC;COSMIC	71.554	Down-regulation
Other_IKK_IKBKE_ST	O43524	FOXO3	Q14164	IKBKE	S257	R264S	264	Missense	distal	7	no	76.074	76.597	EPSD	TCGA;ICGC;COSMIC	71.554	Up-regulation
Other_IKK_IKBKE_ST	O43524	FOXO3	Q14164	IKBKE	S257	R250W	250	Missense	distal	-7	no	76.074	78.730	EPSD	TCGA;ICGC;COSMIC	71.554	Up-regulation
Other_IKK_IKBKE_ST	O43524	FOXO3	Q14164	IKBKE	S257	R250Q	250	Missense	distal	-7	no	76.074	77.126	EPSD	TCGA;ICGC;COSMIC	71.554	Up-regulation
Other_IKK_IKBKE_ST	O43524	FOXO3	Q14164	IKBKE	S299	L303M	303	Missense	distal	4	no	55.046	72.114	EPSD	TCGA;ICGC	71.554	Gain
Other_IKK_IKBKE_ST	O43524	FOXO3	Q14164	IKBKE	T313	R310C	310	Missense	distal	-3	no	78.900	77.495	EPSD	TCGA;ICGC;COSMIC	71.554	Down-regulation
Other_IKK_IKBKE_ST	O43524	FOXO3	Q14164	IKBKE	T313	D308Y	308	Missense	distal	-5	no	78.900	74.025	EPSD	TCGA;ICGC;COSMIC	71.554	Down-regulation
Other_IKK_IKBKE_ST	O43524	FOXO3	Q14164	IKBKE	T313	S315F	315	Missense	proximal	2	no	78.900	72.792	EPSD	TCGA;ICGC;COSMIC	71.554	Down-regulation
Other_IKK_IKBKE_ST	O43524	FOXO3	Q14164	IKBKE	T313	R312C	312	Missense	proximal	-1	no	78.900	71.818	EPSD	TCGA;ICGC;COSMIC	71.554	Down-regulation
Other_IKK_IKBKE_ST	O43524	FOXO3	Q14164	IKBKE	S325	R323L	323	Missense	proximal	-2	no	65.302	85.903	EPSD	TCGA;ICGC;COSMIC	71.554	Gain
Other_IKK_IKBKE_ST	O43524	FOXO3	Q14164	IKBKE	S355	C362F	362	Missense	distal	7	no	72.533	72.326	EPSD	TCGA;ICGC;COSMIC	71.554	Down-regulation
Other_IKK_IKBKE_ST	O43524	FOXO3	Q14164	IKBKE	S425	L423M	423	Missense	proximal	-2	no	79.149	78.604	EPSD	TCGA;ICGC	71.554	Down-regulation
Other_IKK_IKBKE_ST	O43524	FOXO3	Q14164	IKBKE	S425	S425F	425	Missense	central	0	yes	79.149	0.000	EPSD	TCGA;ICGC;COSMIC	71.554	Loss
Other_IKK_IKBKE_ST	O43524	FOXO3	Q14164	IKBKE	S429	G436R	436	Missense	distal	7	no	74.376	72.856	EPSD	TCGA;ICGC;COSMIC;GDSC;CCLE	71.554	Down-regulation
Other_IKK_IKBKE_ST	O43524	FOXO3	Q14164	IKBKE	S429	L423M	423	Missense	distal	-6	no	74.376	72.311	EPSD	TCGA;ICGC	71.554	Down-regulation
Other_IKK_IKBKE_ST	O43524	FOXO3	Q14164	IKBKE	S429	S425F	425	Missense	distal	-4	no	74.376	73.019	EPSD	TCGA;ICGC;COSMIC	71.554	Down-regulation
Other_IKK_IKBKE_ST	O43524	FOXO3	Q14164	IKBKE	S429	V434M	434	Missense	distal	5	no	74.376	75.636	EPSD	TCGA;ICGC;COSMIC	71.554	Up-regulation
Other_IKK_IKBKE_ST	O43524	FOXO3	Q14164	IKBKE	S432	G436R	436	Missense	distal	4	no	74.413	70.774	EPSD	TCGA;ICGC;COSMIC;GDSC;CCLE	71.554	Loss
Other_IKK_IKBKE_ST	O43524	FOXO3	Q14164	IKBKE	S432	S425F	425	Missense	distal	-7	no	74.413	75.356	EPSD	TCGA;ICGC;COSMIC	71.554	Up-regulation
Other_IKK_IKBKE_ST	O43524	FOXO3	Q14164	IKBKE	S432	V434M	434	Missense	proximal	2	no	74.413	72.993	EPSD	TCGA;ICGC;COSMIC	71.554	Down-regulation
Other_IKK_IKBKE_ST	O43524	FOXO3	Q14164	IKBKE	S438	G436R	436	Missense	proximal	-2	no	78.933	65.695	EPSD	TCGA;ICGC;COSMIC;GDSC;CCLE	71.554	Loss
Other_IKK_IKBKE_ST	O43524	FOXO3	Q14164	IKBKE	S438	V434M	434	Missense	distal	-4	no	78.933	81.130	EPSD	TCGA;ICGC;COSMIC	71.554	Up-regulation
Other_IKK_IKBKE_ST	O43524	FOXO3	Q14164	IKBKE	S442	G436R	436	Missense	distal	-6	no	81.488	79.404	EPSD	TCGA;ICGC;COSMIC;GDSC;CCLE	71.554	Down-regulation
Other_IKK_IKBKE_ST	O43524	FOXO3	Q14164	IKBKE	S442	Q449H	449	Missense	distal	7	no	81.488	82.817	EPSD	TCGA;ICGC;COSMIC	71.554	Up-regulation
Other_IKK_IKBKE_ST	O43524	FOXO3	Q14164	IKBKE	S574	M580I	580	Missense	distal	6	no	81.169	68.509	EPSD	TCGA;ICGC;COSMIC	71.554	Loss
Other_IKK_IKBKE_ST	O43524	FOXO3	Q14164	IKBKE	S644	N650S	650	Missense	distal	6	no	92.654	99.068	PhosphoSitePlus	TCGA;ICGC;COSMIC	71.554	Up-regulation
Other_IKK_IKBKE_ST	P49840	GSK3A	Q14164	IKBKE	S401	R407Q	407	Missense	distal	6	no	78.685	78.709	EPSD	TCGA;ICGC;COSMIC	71.554	Up-regulation
Other_IKK_IKBKE_ST	Q9UNN5	FAF1	Q14164	IKBKE	S289	D290N	290	Missense	proximal	1	no	72.465	83.517	EPSD	TCGA;ICGC;COSMIC	71.554	Up-regulation
Other_IKK_IKBKE_ST	Q9UNN5	FAF1	Q14164	IKBKE	S289	V285A	285	Missense	distal	-4	no	72.465	69.906	EPSD	TCGA;ICGC	71.554	Loss
Other_IKK_IKBKE_ST	Q9UNN5	FAF1	Q14164	IKBKE	S314	A313V	313	Missense	proximal	-1	no	77.414	83.390	EPSD	TCGA;ICGC;COSMIC	71.554	Up-regulation
Other_IKK_IKBKE_ST	Q9UNN5	FAF1	Q14164	IKBKE	S314	A316V	316	Missense	proximal	2	no	77.414	81.932	EPSD	TCGA;ICGC;COSMIC	71.554	Up-regulation
CMGC_MAPK_p38_MAPK12_ST	Q12959	DLG1	P53778	MAPK12	S100	E95Q	95	Missense	distal	-5	no	116.422	116.438	EPSD	TCGA;ICGC;COSMIC	112.929	Up-regulation
CMGC_MAPK_p38_MAPK12_ST	Q12959	DLG1	P53778	MAPK12	S100	S100C	100	Missense	central	0	yes	116.422	0.000	EPSD	TCGA;ICGC;COSMIC	112.929	Loss
CMGC_MAPK_p38_MAPK12_ST	Q12959	DLG1	P53778	MAPK12	S102	E95Q	95	Missense	distal	-7	no	120.826	120.221	EPSD	TCGA;ICGC;COSMIC	112.929	Down-regulation
CMGC_MAPK_p38_MAPK12_ST	Q12959	DLG1	P53778	MAPK12	S102	S100C	100	Missense	proximal	-2	no	120.826	111.548	EPSD	TCGA;ICGC;COSMIC	112.929	Loss
CMGC_MAPK_p38_MAPK12_ST	Q12959	DLG1	P53778	MAPK12	T115	D112N	112	Missense	distal	-3	no	119.323	118.851	EPSD	TCGA;ICGC;COSMIC	112.929	Down-regulation
CMGC_MAPK_p38_MAPK12_ST	Q12959	DLG1	P53778	MAPK12	T115	P116L	116	Missense	proximal	1	no	119.323	102.578	EPSD	TCGA;ICGC;COSMIC	112.929	Loss
CMGC_MAPK_p38_MAPK12_ST	Q12959	DLG1	P53778	MAPK12	T115	P116S	116	Missense	proximal	1	no	119.323	48.838	EPSD	TCGA;ICGC;COSMIC	112.929	Loss
CMGC_MAPK_p38_MAPK12_ST	Q12959	DLG1	P53778	MAPK12	S122	P116L	116	Missense	distal	-6	no	120.748	123.771	PhosphoSitePlus;EPSD	TCGA;ICGC;COSMIC	112.929	Up-regulation
CMGC_MAPK_p38_MAPK12_ST	Q12959	DLG1	P53778	MAPK12	S122	P116S	116	Missense	distal	-6	no	120.748	120.719	PhosphoSitePlus;EPSD	TCGA;ICGC;COSMIC	112.929	Down-regulation
CMGC_MAPK_p38_MAPK12_ST	Q12959	DLG1	P53778	MAPK12	S158	A165S	165	Missense	distal	7	no	133.815	133.583	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	112.929	Down-regulation
CMGC_MAPK_p38_MAPK12_ST	Q12959	DLG1	P53778	MAPK12	T209	E208Q	208	Missense	proximal	-1	no	136.800	137.248	EPSD;PhosphoSitePlus	TCGA;COSMIC	112.929	Up-regulation
CMGC_MAPK_p38_MAPK12_ST	Q12959	DLG1	P53778	MAPK12	S232	F236L	236	Missense	distal	4	no	113.175	113.976	EPSD	TCGA;COSMIC	112.929	Up-regulation
CMGC_MAPK_p38_MAPK12_ST	Q12959	DLG1	P53778	MAPK12	S432	D428H	428	Missense	distal	-4	no	137.071	129.471	EPSD	TCGA;COSMIC	112.929	Down-regulation
CMGC_MAPK_p38_MAPK12_ST	Q12959	DLG1	P53778	MAPK12	S432	S432G	432	Missense	central	0	yes	137.071	0.000	EPSD	TCGA;COSMIC	112.929	Loss
CMGC_MAPK_p38_MAPK12_ST	Q12959	DLG1	P53778	MAPK12	T440	A442V	442	Missense	proximal	2	no	125.159	124.144	EPSD	TCGA;COSMIC	112.929	Down-regulation
CMGC_MAPK_p38_MAPK12_ST	Q12959	DLG1	P53778	MAPK12	S443	A442V	442	Missense	proximal	-1	no	145.026	143.561	EPSD;PhosphoSitePlus	TCGA;COSMIC	112.929	Down-regulation
CMGC_MAPK_p38_MAPK12_ST	Q12959	DLG1	P53778	MAPK12	S448	A442V	442	Missense	distal	-6	no	115.530	118.162	EPSD	TCGA;COSMIC	112.929	Up-regulation
CMGC_MAPK_p38_MAPK12_ST	Q12959	DLG1	P53778	MAPK12	S583	R587I	587	Missense	distal	4	no	118.139	119.000	EPSD	TCGA;COSMIC	112.929	Up-regulation
CMGC_MAPK_p38_MAPK12_ST	Q00613	HSF1	P53778	MAPK12	S244	S250C	250	Missense	distal	6	no	127.884	126.701	EPSD	TCGA;COSMIC	112.929	Down-regulation
CMGC_MAPK_p38_MAPK12_ST	Q00613	HSF1	P53778	MAPK12	S251	S250C	250	Missense	proximal	-1	no	114.466	111.353	EPSD	TCGA;COSMIC	112.929	Loss
CMGC_MAPK_p38_MAPK12_ST	Q00613	HSF1	P53778	MAPK12	S251	A254T	254	Missense	distal	3	no	114.466	114.165	EPSD	TCGA;COSMIC;CCLE	112.929	Down-regulation
CMGC_MAPK_p38_MAPK12_ST	Q00613	HSF1	P53778	MAPK12	S275	P276L	276	Missense	proximal	1	no	135.072	118.327	EPSD	TCGA;COSMIC	112.929	Down-regulation
CMGC_MAPK_p38_MAPK12_ST	Q00613	HSF1	P53778	MAPK12	S275	M277V	277	Missense	proximal	2	no	135.072	134.574	EPSD	TCGA;COSMIC	112.929	Down-regulation
CMGC_MAPK_p38_MAPK12_ST	Q00613	HSF1	P53778	MAPK12	S279	P276L	276	Missense	distal	-3	no	130.024	129.563	EPSD	TCGA;COSMIC	112.929	Down-regulation
CMGC_MAPK_p38_MAPK12_ST	Q00613	HSF1	P53778	MAPK12	S279	E286K	286	Missense	distal	7	no	130.024	131.549	EPSD	TCGA;COSMIC	112.929	Up-regulation
CMGC_MAPK_p38_MAPK12_ST	Q00613	HSF1	P53778	MAPK12	S279	M277V	277	Missense	proximal	-2	no	130.024	129.964	EPSD	TCGA;COSMIC	112.929	Down-regulation
CMGC_MAPK_p38_MAPK12_ST	Q00613	HSF1	P53778	MAPK12	S292	R296C	296	Missense	distal	4	no	125.557	124.998	EPSD	TCGA;COSMIC	112.929	Down-regulation
CMGC_MAPK_p38_MAPK12_ST	Q00613	HSF1	P53778	MAPK12	S292	P288L	288	Missense	distal	-4	no	125.557	123.756	EPSD	TCGA;COSMIC	112.929	Down-regulation
CMGC_MAPK_p38_MAPK12_ST	Q00613	HSF1	P53778	MAPK12	S292	E286K	286	Missense	distal	-6	no	125.557	123.295	EPSD	TCGA;COSMIC	112.929	Down-regulation
CMGC_MAPK_p38_MAPK12_ST	Q00613	HSF1	P53778	MAPK12	S303	E300Q	300	Missense	distal	-3	no	135.892	136.204	EPSD;PhosphoSitePlus	TCGA	112.929	Up-regulation
CMGC_MAPK_p38_MAPK12_ST	Q00613	HSF1	P53778	MAPK12	S303	R296C	296	Missense	distal	-7	no	135.892	136.324	EPSD;PhosphoSitePlus	TCGA;COSMIC	112.929	Up-regulation
CMGC_MAPK_p38_MAPK12_ST	Q00613	HSF1	P53778	MAPK12	S307	E300Q	300	Missense	distal	-7	no	139.350	138.745	PhosphoSitePlus;EPSD	TCGA	112.929	Down-regulation
CMGC_MAPK_p38_MAPK12_ST	Q00613	HSF1	P53778	MAPK12	S314	R317H	317	Missense	distal	3	no	116.105	116.378	EPSD	TCGA;COSMIC	112.929	Up-regulation
CMGC_MAPK_p38_MAPK12_ST	Q00613	HSF1	P53778	MAPK12	S314	S320F	320	Missense	distal	6	no	116.105	114.712	EPSD	TCGA;COSMIC	112.929	Down-regulation
CMGC_MAPK_p38_MAPK12_ST	Q00613	HSF1	P53778	MAPK12	S326	D332Y	332	Missense	distal	6	no	132.568	132.415	EPSD;PhosphoSitePlus	TCGA;COSMIC	112.929	Down-regulation
CMGC_MAPK_p38_MAPK12_ST	Q00613	HSF1	P53778	MAPK12	S326	T323I	323	Missense	distal	-3	no	132.568	132.879	EPSD;PhosphoSitePlus	TCGA;COSMIC	112.929	Up-regulation
CMGC_MAPK_p38_MAPK12_ST	Q00613	HSF1	P53778	MAPK12	S326	S320F	320	Missense	distal	-6	no	132.568	136.134	EPSD;PhosphoSitePlus	TCGA;COSMIC	112.929	Up-regulation
CMGC_MAPK_p38_MAPK12_ST	Q00613	HSF1	P53778	MAPK12	S326	A329T	329	Missense	distal	3	no	132.568	132.267	EPSD;PhosphoSitePlus	TCGA;COSMIC	112.929	Down-regulation
CMGC_MAPK_p38_MAPK12_ST	Q00613	HSF1	P53778	MAPK12	S326	S333F	333	Missense	distal	7	no	132.568	130.991	EPSD;PhosphoSitePlus	TCGA;COSMIC	112.929	Down-regulation
CMGC_MAPK_p38_MAPK12_ST	Q00613	HSF1	P53778	MAPK12	S326	P327L	327	Missense	proximal	1	no	132.568	115.823	EPSD;PhosphoSitePlus	TCGA	112.929	Down-regulation
CMGC_MAPK_p38_MAPK12_ST	Q00613	HSF1	P53778	MAPK12	S363	P364S	364	Missense	proximal	1	no	129.909	59.423	EPSD	TCGA;COSMIC	112.929	Loss
CMGC_MAPK_p38_MAPK12_ST	Q00613	HSF1	P53778	MAPK12	T369	P364S	364	Missense	distal	-5	no	118.876	118.921	EPSD	TCGA;COSMIC	112.929	Up-regulation
CMGC_MAPK_p38_MAPK12_ST	Q00613	HSF1	P53778	MAPK12	S419	P420L	420	Missense	proximal	1	no	129.769	113.024	EPSD	TCGA;ICGC;COSMIC	112.929	Down-regulation
CMGC_MAPK_p38_MAPK12_ST	Q00613	HSF1	P53778	MAPK12	S419	P425S	425	Missense	distal	6	no	129.769	130.074	EPSD	TCGA;ICGC;COSMIC	112.929	Up-regulation
CMGC_MAPK_p38_MAPK12_ST	Q00613	HSF1	P53778	MAPK12	S444	E441K	441	Missense	distal	-3	no	122.921	123.466	EPSD	TCGA;COSMIC	112.929	Up-regulation
CMGC_MAPK_p38_MAPK12_ST	Q00613	HSF1	P53778	MAPK12	S458	E453K	453	Missense	distal	-5	no	120.860	121.090	EPSD	TCGA;COSMIC	112.929	Up-regulation
CMGC_MAPK_p38_MAPK12_ST	Q00613	HSF1	P53778	MAPK12	S513	A507V	507	Missense	distal	-6	no	113.772	116.404	EPSD	TCGA;ICGC;COSMIC	112.929	Up-regulation
CMGC_MAPK_p38_MAPK12_ST	P35222	CTNNB1	P53778	MAPK12	S33	G34R	34	Missense	proximal	1	no	120.324	-49.041	EPSD	TCGA;COSMIC	112.929	Loss
CMGC_MAPK_p38_MAPK12_ST	P35222	CTNNB1	P53778	MAPK12	S33	G34V	34	Missense	proximal	1	no	120.324	58.653	EPSD	TCGA;COSMIC;CCLE	112.929	Loss
CMGC_MAPK_p38_MAPK12_ST	P35222	CTNNB1	P53778	MAPK12	S33	G34E	34	Missense	proximal	1	no	120.324	-76.763	EPSD	TCGA;COSMIC;GDSC;CCLE	112.929	Loss
CMGC_MAPK_p38_MAPK12_ST	P35222	CTNNB1	P53778	MAPK12	S33	S37C	37	Missense	distal	4	no	120.324	118.813	EPSD	TCGA;COSMIC;GDSC;CCLE	112.929	Down-regulation
CMGC_MAPK_p38_MAPK12_ST	P35222	CTNNB1	P53778	MAPK12	S33	S37F	37	Missense	distal	4	no	120.324	118.715	EPSD	TCGA;COSMIC;GDSC;CCLE	112.929	Down-regulation
CMGC_MAPK_p38_MAPK12_ST	P35222	CTNNB1	P53778	MAPK12	S33	S33F	33	Missense	central	0	yes	120.324	0.000	EPSD	TCGA;COSMIC;GDSC;CCLE	112.929	Loss
CMGC_MAPK_p38_MAPK12_ST	P35222	CTNNB1	P53778	MAPK12	S33	D32H	32	Missense	proximal	-1	no	120.324	118.155	EPSD	TCGA;COSMIC	112.929	Down-regulation
CMGC_MAPK_p38_MAPK12_ST	P35222	CTNNB1	P53778	MAPK12	S33	D32G	32	Missense	proximal	-1	no	120.324	119.621	EPSD	TCGA;COSMIC	112.929	Down-regulation
CMGC_MAPK_p38_MAPK12_ST	P35222	CTNNB1	P53778	MAPK12	S33	S33A	33	Missense	central	0	yes	120.324	0.000	EPSD	TCGA;COSMIC	112.929	Loss
CMGC_MAPK_p38_MAPK12_ST	P35222	CTNNB1	P53778	MAPK12	S33	S33Y	33	Missense	central	0	yes	120.324	0.000	EPSD	TCGA;COSMIC;GDSC;CCLE	112.929	Loss
CMGC_MAPK_p38_MAPK12_ST	P35222	CTNNB1	P53778	MAPK12	S33	D32V	32	Missense	proximal	-1	no	120.324	117.583	EPSD	TCGA;COSMIC;CCLE	112.929	Down-regulation
CMGC_MAPK_p38_MAPK12_ST	P35222	CTNNB1	P53778	MAPK12	S33	S33P	33	Missense	central	0	yes	120.324	0.000	EPSD	TCGA;COSMIC;CCLE	112.929	Loss
CMGC_MAPK_p38_MAPK12_ST	P35222	CTNNB1	P53778	MAPK12	S33	H36P	36	Missense	distal	3	no	120.324	120.564	EPSD	TCGA;COSMIC;CCLE	112.929	Up-regulation
CMGC_MAPK_p38_MAPK12_ST	P35222	CTNNB1	P53778	MAPK12	S33	D32Y	32	Missense	proximal	-1	no	120.324	119.259	EPSD	TCGA;COSMIC;CCLE	112.929	Down-regulation
CMGC_MAPK_p38_MAPK12_ST	P35222	CTNNB1	P53778	MAPK12	S33	I35S	35	Missense	proximal	2	no	120.324	120.274	EPSD	TCGA;COSMIC	112.929	Down-regulation
CMGC_MAPK_p38_MAPK12_ST	P35222	CTNNB1	P53778	MAPK12	S33	S37Y	37	Missense	distal	4	no	120.324	120.433	EPSD	TCGA;COSMIC	112.929	Up-regulation
CMGC_MAPK_p38_MAPK12_ST	P35222	CTNNB1	P53778	MAPK12	S33	S33C	33	Missense	central	0	yes	120.324	0.000	EPSD	TCGA;COSMIC;GDSC;CCLE	112.929	Loss
CMGC_MAPK_p38_MAPK12_ST	P35222	CTNNB1	P53778	MAPK12	S33	S37A	37	Missense	distal	4	no	120.324	120.546	EPSD	TCGA;COSMIC;GDSC;CCLE	112.929	Up-regulation
CMGC_MAPK_p38_MAPK12_ST	P35222	CTNNB1	P53778	MAPK12	S33	D32N	32	Missense	proximal	-1	no	120.324	119.316	EPSD	TCGA;COSMIC;CCLE	112.929	Down-regulation
CMGC_MAPK_p38_MAPK12_ST	P35222	CTNNB1	P53778	MAPK12	S33	S37P	37	Missense	distal	4	no	120.324	120.064	EPSD	TCGA;COSMIC;GDSC;CCLE	112.929	Down-regulation
CMGC_MAPK_p38_MAPK12_ST	P35222	CTNNB1	P53778	MAPK12	S33	D32A	32	Missense	proximal	-1	no	120.324	119.048	EPSD	TCGA;COSMIC	112.929	Down-regulation
CMGC_MAPK_p38_MAPK12_ST	P35222	CTNNB1	P53778	MAPK12	S45	T41I	41	Missense	distal	-4	no	111.386	113.893	EPSD	TCGA;COSMIC	112.929	Gain
CMGC_MAPK_p38_MAPK12_ST	P35222	CTNNB1	P53778	MAPK12	S47	S45P	45	Missense	proximal	-2	no	112.459	115.408	EPSD	TCGA;COSMIC;CCLE	112.929	Gain
CMGC_MAPK_p38_MAPK12_ST	P35222	CTNNB1	P53778	MAPK12	S47	S45Y	45	Missense	proximal	-2	no	112.459	113.329	EPSD	TCGA;COSMIC	112.929	Gain
CMGC_MAPK_p38_MAPK12_ST	P35222	CTNNB1	P53778	MAPK12	S47	E54D	54	Missense	distal	7	no	112.459	113.841	EPSD	TCGA;COSMIC	112.929	Gain
CMGC_MAPK_p38_MAPK12_ST	P35222	CTNNB1	P53778	MAPK12	T102	M98V	98	Missense	distal	-4	no	113.879	110.415	EPSD	TCGA;COSMIC	112.929	Loss
CMGC_MAPK_p38_MAPK12_ST	P35222	CTNNB1	P53778	MAPK12	T102	E101D	101	Missense	proximal	-1	no	113.879	116.789	EPSD	TCGA	112.929	Up-regulation
CMGC_MAPK_p38_MAPK12_ST	P35222	CTNNB1	P53778	MAPK12	S191	A197S	197	Missense	distal	6	no	120.489	120.626	EPSD	TCGA;COSMIC	112.929	Up-regulation
CMGC_MAPK_p38_MAPK12_ST	P35222	CTNNB1	P53778	MAPK12	S191	R185G	185	Missense	distal	-6	no	120.489	119.263	EPSD	TCGA;COSMIC	112.929	Down-regulation
CMGC_MAPK_p38_MAPK12_ST	P35222	CTNNB1	P53778	MAPK12	T258	I256M	256	Missense	proximal	-2	no	117.276	112.062	EPSD	TCGA;COSMIC	112.929	Loss
CMGC_MAPK_p38_MAPK12_ST	P35222	CTNNB1	P53778	MAPK12	T258	I256T	256	Missense	proximal	-2	no	117.276	113.348	EPSD	TCGA;COSMIC	112.929	Down-regulation
CMGC_MAPK_p38_MAPK12_ST	P35222	CTNNB1	P53778	MAPK12	T258	L259H	259	Missense	proximal	1	no	117.276	0.207	EPSD	TCGA;COSMIC	112.929	Loss
CMGC_MAPK_p38_MAPK12_ST	P35222	CTNNB1	P53778	MAPK12	S605	P606L	606	Missense	proximal	1	no	132.393	115.648	PhosphoSitePlus	TCGA;COSMIC	112.929	Down-regulation
CMGC_MAPK_p38_MAPK12_ST	P10636	MAPT	P53778	MAPK12	S46	T52I	52	Missense	distal	6	no	119.116	119.548	EPSD	TCGA;ICGC;COSMIC	112.929	Up-regulation
CMGC_MAPK_p38_MAPK12_ST	P10636	MAPT	P53778	MAPK12	S46	P47S	47	Missense	proximal	1	no	119.116	48.631	EPSD	TCGA;ICGC;COSMIC	112.929	Loss
CMGC_MAPK_p38_MAPK12_ST	P10636	MAPT	P53778	MAPK12	S46	P47L	47	Missense	proximal	1	no	119.116	102.371	EPSD	TCGA;ICGC;COSMIC	112.929	Loss
CMGC_MAPK_p38_MAPK12_ST	P10636	MAPT	P53778	MAPK12	S46	G42C	42	Missense	distal	-4	no	119.116	111.082	EPSD	TCGA;ICGC;COSMIC	112.929	Loss
CMGC_MAPK_p38_MAPK12_ST	P10636	MAPT	P53778	MAPK12	T50	D54E	54	Missense	distal	4	no	134.448	132.974	EPSD	TCGA;ICGC;COSMIC	112.929	Down-regulation
CMGC_MAPK_p38_MAPK12_ST	P10636	MAPT	P53778	MAPK12	T50	T52I	52	Missense	proximal	2	no	134.448	134.895	EPSD	TCGA;ICGC;COSMIC	112.929	Up-regulation
CMGC_MAPK_p38_MAPK12_ST	P10636	MAPT	P53778	MAPK12	T50	P47S	47	Missense	distal	-3	no	134.448	134.669	EPSD	TCGA;ICGC;COSMIC	112.929	Up-regulation
CMGC_MAPK_p38_MAPK12_ST	P10636	MAPT	P53778	MAPK12	T50	P47L	47	Missense	distal	-3	no	134.448	133.987	EPSD	TCGA;ICGC;COSMIC	112.929	Down-regulation
CMGC_MAPK_p38_MAPK12_ST	P10636	MAPT	P53778	MAPK12	T50	G55R	55	Missense	distal	5	no	134.448	133.611	EPSD	TCGA;ICGC;COSMIC	112.929	Down-regulation
CMGC_MAPK_p38_MAPK12_ST	P10636	MAPT	P53778	MAPK12	T69	A72V	72	Missense	distal	3	no	139.605	138.542	EPSD	TCGA;ICGC;COSMIC	112.929	Down-regulation
CMGC_MAPK_p38_MAPK12_ST	P10636	MAPT	P53778	MAPK12	T69	A66S	66	Missense	distal	-3	no	139.605	139.897	EPSD	TCGA;ICGC;COSMIC	112.929	Up-regulation
CMGC_MAPK_p38_MAPK12_ST	P10636	MAPT	P53778	MAPK12	T111	E117K	117	Missense	distal	6	no	138.577	139.196	EPSD	TCGA;ICGC;COSMIC	112.929	Up-regulation
CMGC_MAPK_p38_MAPK12_ST	P10636	MAPT	P53778	MAPK12	T111	A118V	118	Missense	distal	7	no	138.577	137.409	EPSD	TCGA;ICGC;COSMIC	112.929	Down-regulation
CMGC_MAPK_p38_MAPK12_ST	P10636	MAPT	P53778	MAPK12	S228	S232Y	232	Missense	distal	4	no	119.197	119.306	EPSD	TCGA;ICGC;COSMIC	112.929	Up-regulation
CMGC_MAPK_p38_MAPK12_ST	P10636	MAPT	P53778	MAPK12	S228	D223Y	223	Missense	distal	-5	no	119.197	119.077	EPSD	TCGA;ICGC;COSMIC	112.929	Down-regulation
CMGC_MAPK_p38_MAPK12_ST	P10636	MAPT	P53778	MAPK12	S228	S227F	227	Missense	proximal	-1	no	119.197	115.838	EPSD	TCGA;ICGC;COSMIC	112.929	Down-regulation
CMGC_MAPK_p38_MAPK12_ST	P10636	MAPT	P53778	MAPK12	S228	P234L	234	Missense	distal	6	no	119.197	118.843	EPSD	TCGA;ICGC;COSMIC	112.929	Down-regulation
CMGC_MAPK_p38_MAPK12_ST	P10636	MAPT	P53778	MAPK12	S232	S232Y	232	Missense	central	0	yes	127.513	0.000	EPSD	TCGA;ICGC;COSMIC	112.929	Loss
CMGC_MAPK_p38_MAPK12_ST	P10636	MAPT	P53778	MAPK12	S232	S227F	227	Missense	distal	-5	no	127.513	127.117	EPSD	TCGA;ICGC;COSMIC	112.929	Down-regulation
CMGC_MAPK_p38_MAPK12_ST	P10636	MAPT	P53778	MAPK12	S232	P234L	234	Missense	proximal	2	no	127.513	126.616	EPSD	TCGA;ICGC;COSMIC	112.929	Down-regulation
CMGC_MAPK_p38_MAPK12_ST	P10636	MAPT	P53778	MAPK12	S238	S232Y	232	Missense	distal	-6	no	124.422	124.620	EPSD	TCGA;ICGC;COSMIC	112.929	Up-regulation
CMGC_MAPK_p38_MAPK12_ST	P10636	MAPT	P53778	MAPK12	S238	A240T	240	Missense	proximal	2	no	124.422	124.237	EPSD	TCGA;ICGC;COSMIC	112.929	Down-regulation
CMGC_MAPK_p38_MAPK12_ST	P10636	MAPT	P53778	MAPK12	S238	P234L	234	Missense	distal	-4	no	124.422	122.622	EPSD	TCGA;ICGC;COSMIC	112.929	Down-regulation
CMGC_MAPK_p38_MAPK12_ST	P10636	MAPT	P53778	MAPK12	S238	R244Q	244	Missense	distal	6	no	124.422	124.432	EPSD	TCGA;ICGC;COSMIC	112.929	Up-regulation
CMGC_MAPK_p38_MAPK12_ST	P10636	MAPT	P53778	MAPK12	T386	G387R	387	Missense	proximal	1	no	114.896	-54.469	EPSD	TCGA;COSMIC	112.929	Loss
CMGC_MAPK_p38_MAPK12_ST	P10636	MAPT	P53778	MAPK12	S411	P415L	415	Missense	distal	4	no	133.123	132.575	EPSD	TCGA;ICGC;COSMIC	112.929	Down-regulation
CMGC_MAPK_p38_MAPK12_ST	P10636	MAPT	P53778	MAPK12	T416	P415L	415	Missense	proximal	-1	no	123.640	122.754	EPSD	TCGA;ICGC;COSMIC	112.929	Down-regulation
CMGC_MAPK_p38_MAPK12_ST	P10636	MAPT	P53778	MAPK12	S428	A430S	430	Missense	proximal	2	no	140.380	140.592	EPSD	TCGA;ICGC;COSMIC	112.929	Up-regulation
CMGC_MAPK_p38_MAPK12_ST	P10636	MAPT	P53778	MAPK12	S428	V431L	431	Missense	distal	3	no	140.380	140.430	EPSD	TCGA;ICGC;COSMIC	112.929	Up-regulation
CMGC_MAPK_p38_MAPK12_ST	P10636	MAPT	P53778	MAPK12	S428	A430V	430	Missense	proximal	2	no	140.380	139.365	EPSD	TCGA;ICGC;COSMIC	112.929	Down-regulation
CMGC_MAPK_p38_MAPK12_ST	P10636	MAPT	P53778	MAPK12	S438	P436T	436	Missense	proximal	-2	no	130.470	123.798	EPSD	TCGA;ICGC;COSMIC	112.929	Down-regulation
CMGC_MAPK_p38_MAPK12_ST	P10636	MAPT	P53778	MAPK12	S438	P436L	436	Missense	proximal	-2	no	130.470	124.815	EPSD	TCGA;ICGC;COSMIC	112.929	Down-regulation
CMGC_MAPK_p38_MAPK12_ST	P10636	MAPT	P53778	MAPK12	S438	K440E	440	Missense	proximal	2	no	130.470	129.419	EPSD	TCGA;ICGC;COSMIC	112.929	Down-regulation
CMGC_MAPK_p38_MAPK12_ST	P10636	MAPT	P53778	MAPK12	S438	S443F	443	Missense	distal	5	no	130.470	128.077	EPSD	TCGA;ICGC;COSMIC	112.929	Down-regulation
CMGC_MAPK_p38_MAPK12_ST	P10636	MAPT	P53778	MAPK12	S438	V431L	431	Missense	distal	-7	no	130.470	130.677	EPSD	TCGA;ICGC;COSMIC	112.929	Up-regulation
CMGC_MAPK_p38_MAPK12_ST	P10636	MAPT	P53778	MAPK12	S438	S444F	444	Missense	distal	6	no	130.470	129.076	EPSD	TCGA;ICGC	112.929	Down-regulation
CMGC_MAPK_p38_MAPK12_ST	P10636	MAPT	P53778	MAPK12	T449	S443F	443	Missense	distal	-6	no	111.333	114.899	EPSD	TCGA;ICGC;COSMIC	112.929	Gain
CMGC_MAPK_p38_MAPK12_ST	P10636	MAPT	P53778	MAPK12	T470	R472Q	472	Missense	proximal	2	no	129.712	129.420	EPSD	TCGA	112.929	Down-regulation
CMGC_MAPK_p38_MAPK12_ST	P10636	MAPT	P53778	MAPK12	T470	R472W	472	Missense	proximal	2	no	129.712	129.673	EPSD	TCGA;COSMIC	112.929	Down-regulation
CMGC_MAPK_p38_MAPK12_ST	P10636	MAPT	P53778	MAPK12	T492	A485T	485	Missense	distal	-7	no	133.001	134.127	EPSD	TCGA;COSMIC;GDSC;CCLE	112.929	Up-regulation
CMGC_MAPK_p38_MAPK12_ST	P10636	MAPT	P53778	MAPK12	T492	P493Q	493	Missense	proximal	1	no	133.001	-65.007	EPSD	TCGA;COSMIC	112.929	Loss
CMGC_MAPK_p38_MAPK12_ST	P10636	MAPT	P53778	MAPK12	T498	P493Q	493	Missense	distal	-5	no	131.414	131.164	EPSD	TCGA;COSMIC	112.929	Down-regulation
CMGC_MAPK_p38_MAPK12_ST	P26045	PTPN3	P53778	MAPK12	S322	Q323P	323	Missense	proximal	1	no	-83.863	114.145	EPSD	TCGA;COSMIC	112.929	Gain
CMGC_MAPK_p38_MAPK12_ST	P26045	PTPN3	P53778	MAPK12	S372	P374S	374	Missense	proximal	2	no	127.394	127.777	EPSD	TCGA;COSMIC	112.929	Up-regulation
CMGC_MAPK_p38_MAPK12_ST	P26045	PTPN3	P53778	MAPK12	T376	P374S	374	Missense	proximal	-2	no	131.251	128.303	EPSD	TCGA;COSMIC	112.929	Down-regulation
CMGC_MAPK_p38_MAPK12_ST	P26045	PTPN3	P53778	MAPK12	S381	P374S	374	Missense	distal	-7	no	118.537	118.278	EPSD	TCGA;COSMIC	112.929	Down-regulation
CMGC_MAPK_p38_MAPK12_ST	P26045	PTPN3	P53778	MAPK12	S381	R385W	385	Missense	distal	4	no	118.537	118.721	EPSD	TCGA;ICGC;COSMIC	112.929	Up-regulation
CMGC_MAPK_p38_MAPK12_ST	P26045	PTPN3	P53778	MAPK12	S434	S439G	439	Missense	distal	5	no	126.560	125.986	EPSD	TCGA;COSMIC	112.929	Down-regulation
CMGC_MAPK_p38_MAPK12_ST	P26045	PTPN3	P53778	MAPK12	S434	L440V	440	Missense	distal	6	no	126.560	126.323	EPSD	TCGA;COSMIC	112.929	Down-regulation
CMGC_MAPK_p38_MAPK12_ST	P26045	PTPN3	P53778	MAPK12	S459	Q452H	452	Missense	distal	-7	no	134.239	133.789	PhosphoSitePlus	TCGA;ICGC	112.929	Down-regulation
CMGC_MAPK_p38_MAPK12_ST	P26045	PTPN3	P53778	MAPK12	S459	P460L	460	Missense	proximal	1	no	134.239	117.493	PhosphoSitePlus	TCGA;COSMIC	112.929	Down-regulation
CMGC_MAPK_p38_MAPK12_ST	P26045	PTPN3	P53778	MAPK12	S459	S454L	454	Missense	distal	-5	no	134.239	133.924	PhosphoSitePlus	TCGA;COSMIC	112.929	Down-regulation
CMGC_MAPK_p38_MAPK12_ST	P26045	PTPN3	P53778	MAPK12	S469	G472S	472	Missense	distal	3	no	126.782	126.991	EPSD	TCGA;ICGC;COSMIC	112.929	Up-regulation
CMGC_MAPK_p38_MAPK12_ST	P26045	PTPN3	P53778	MAPK12	S469	S467F	467	Missense	proximal	-2	no	126.782	115.207	EPSD	TCGA;COSMIC;CCLE	112.929	Down-regulation
CMGC_MAPK_p38_MAPK12_ST	P26045	PTPN3	P53778	MAPK12	S469	G472D	472	Missense	distal	3	no	126.782	127.652	EPSD	TCGA;ICGC;COSMIC	112.929	Up-regulation
CMGC_MAPK_p38_MAPK12_ST	P26045	PTPN3	P53778	MAPK12	S469	G472C	472	Missense	distal	3	no	126.782	126.253	EPSD	TCGA;COSMIC	112.929	Down-regulation
CMGC_MAPK_p38_MAPK12_ST	P26045	PTPN3	P53778	MAPK12	S544	A546V	546	Missense	proximal	2	no	126.321	125.306	EPSD	TCGA;ICGC;COSMIC	112.929	Down-regulation
CMGC_MAPK_p38_MAPK12_ST	P26045	PTPN3	P53778	MAPK12	S544	P551R	551	Missense	distal	7	no	126.321	125.714	EPSD	TCGA;ICGC;COSMIC	112.929	Down-regulation
CMGC_MAPK_p38_MAPK12_ST	P26045	PTPN3	P53778	MAPK12	S544	E543A	543	Missense	proximal	-1	no	126.321	127.956	EPSD	TCGA	112.929	Up-regulation
CMGC_MAPK_p38_MAPK12_ST	O43464	HTRA2	P53778	MAPK12	T54	R60W	60	Missense	distal	6	no	121.041	121.192	EPSD	TCGA;ICGC;COSMIC;CCLE	112.929	Up-regulation
CMGC_MAPK_p38_MAPK12_ST	O43464	HTRA2	P53778	MAPK12	S56	R60W	60	Missense	distal	4	no	114.508	114.692	EPSD	TCGA;ICGC;COSMIC;CCLE	112.929	Up-regulation
CMGC_MAPK_p38_MAPK12_ST	P07900	HSP90AA1	P53778	MAPK12	S470	D472H	472	Missense	proximal	2	no	114.747	113.616	EPSD	TCGA;COSMIC	112.929	Down-regulation
CMGC_MAPK_p38_MAPK12_ST	P30281	CCND3	P53778	MAPK12	S133	I126M	126	Missense	distal	-7	no	123.799	125.034	EPSD	TCGA;COSMIC	112.929	Up-regulation
CMGC_MAPK_p38_MAPK12_ST	P30281	CCND3	P53778	MAPK12	S133	R135L	135	Missense	proximal	2	no	123.799	123.210	EPSD	TCGA;COSMIC	112.929	Down-regulation
CMGC_MAPK_p38_MAPK12_ST	P30281	CCND3	P53778	MAPK12	S264	P265T	265	Missense	proximal	1	no	126.610	-4.602	EPSD	TCGA;COSMIC	112.929	Loss
CMGC_MAPK_p38_MAPK12_ST	P30281	CCND3	P53778	MAPK12	S264	S263C	263	Missense	proximal	-1	no	126.610	123.497	EPSD	TCGA;COSMIC	112.929	Down-regulation
CMGC_MAPK_p38_MAPK12_ST	P30281	CCND3	P53778	MAPK12	S264	Q260E	260	Missense	distal	-4	no	126.610	121.175	EPSD	TCGA;COSMIC	112.929	Down-regulation
CMGC_MAPK_p38_MAPK12_ST	P30281	CCND3	P53778	MAPK12	S264	T261S	261	Missense	distal	-3	no	126.610	126.987	EPSD	TCGA;ICGC;COSMIC	112.929	Up-regulation
CMGC_MAPK_p38_MAPK12_ST	P30281	CCND3	P53778	MAPK12	S264	A266V	266	Missense	proximal	2	no	126.610	125.596	EPSD	TCGA;ICGC;COSMIC;GDSC	112.929	Down-regulation
CMGC_MAPK_p38_MAPK12_ST	P30281	CCND3	P53778	MAPK12	T283	P278R	278	Missense	distal	-5	no	130.221	130.016	PhosphoSitePlus	TCGA;COSMIC	112.929	Down-regulation
CMGC_MAPK_p38_MAPK12_ST	P30281	CCND3	P53778	MAPK12	T283	T283A	283	Missense	central	0	yes	130.221	0.000	PhosphoSitePlus	TCGA;ICGC;COSMIC;CCLE	112.929	Loss
CMGC_MAPK_p38_MAPK12_ST	P30281	CCND3	P53778	MAPK12	T283	V287I	287	Missense	distal	4	no	130.221	131.008	PhosphoSitePlus	TCGA;COSMIC	112.929	Up-regulation
STE_STE7_MEK4_MAP2K4_ST	P53779	MAPK10	P45985	MAP2K4	T216	G209R	209	Missense	distal	-7	no	0.005	0.006	EPSD	TCGA;COSMIC	0.006	Gain
STE_STE7_MEK4_MAP2K4_ST	P53779	MAPK10	P45985	MAP2K4	T216	M219I	219	Missense	distal	3	no	0.005	0.007	EPSD	TCGA;COSMIC	0.006	Gain
STE_STE7_MEK4_MAP2K4_ST	P53779	MAPK10	P45985	MAP2K4	T221	G215S	215	Missense	distal	-6	no	0.031	0.032	EPSD	TCGA;COSMIC	0.006	Up-regulation
STE_STE7_MEK4_MAP2K4_ST	P53779	MAPK10	P45985	MAP2K4	T281	P282L	282	Missense	proximal	1	no	0.006	0.005	EPSD	TCGA;COSMIC	0.006	Loss
STE_STE7_MEK4_MAP2K4_ST	P53779	MAPK10	P45985	MAP2K4	T281	K274R	274	Missense	distal	-7	no	0.006	0.007	EPSD	TCGA;COSMIC	0.006	Up-regulation
STE_STE7_MEK4_MAP2K4_ST	P45983	MAPK8	P45985	MAP2K4	T243	E247Q	247	Missense	distal	4	no	0.005	0.006	EPSD	TCGA;ICGC;COSMIC	0.006	Gain
STE_STE7_MEK4_MAP2K4_ST	P45983	MAPK8	P45985	MAP2K4	T243	E239Q	239	Missense	distal	-4	no	0.005	0.006	EPSD	TCGA;ICGC;COSMIC	0.006	Gain
STE_STE7_MEK4_MAP2K4_ST	P45983	MAPK8	P45985	MAP2K4	T243	P246A	246	Missense	distal	3	no	0.005	0.008	EPSD	TCGA;ICGC;COSMIC	0.006	Gain
STE_STE7_MEK4_MAP2K4_ST	Q16539	MAPK14	P45985	MAP2K4	T180	R173W	173	Missense	distal	-7	no	0.026	0.025	PhosphoSitePlus;EPSD	TCGA;ICGC;CCLE	0.006	Down-regulation
STE_STE7_MEK4_MAP2K4_ST	Q16539	MAPK14	P45985	MAP2K4	T263	P266L	266	Missense	distal	3	no	0.004	0.007	EPSD	TCGA;COSMIC	0.006	Gain
STE_STE7_MEK4_MAP2K4_ST	P45984	MAPK9	P45985	MAP2K4	T178	M181I	181	Missense	distal	3	no	0.005	0.006	EPSD	TCGA;ICGC;COSMIC	0.006	Gain
STE_STE7_MEK4_MAP2K4_ST	P45984	MAPK9	P45985	MAP2K4	T183	A176V	176	Missense	distal	-7	no	0.031	0.032	EPSD	TCGA;ICGC;COSMIC	0.006	Up-regulation
STE_STE7_MEK4_MAP2K4_ST	P45984	MAPK9	P45985	MAP2K4	T183	T183A	183	Missense	central	0	yes	0.031	0.000	EPSD	TCGA;ICGC;COSMIC	0.006	Loss
STE_STE7_MEK4_MAP2K4_ST	P45984	MAPK9	P45985	MAP2K4	T404	T404M	404	Missense	central	0	yes	0.006	0.000	EPSD	TCGA;ICGC;COSMIC	0.006	Loss
STE_STE7_MEK4_MAP2K4_ST	P45984	MAPK9	P45985	MAP2K4	T409	D410Y	410	Missense	proximal	1	no	0.007	0.006	EPSD	TCGA;ICGC;COSMIC	0.006	Down-regulation
STE_STE7_MEK4_MAP2K4_ST	P19793	RXRA	P45985	MAP2K4	T82	M77V	77	Missense	distal	-5	no	0.006	0.005	EPSD	TCGA;ICGC	0.006	Loss
STE_STE7_MEK4_MAP2K4_ST	P45985	MAP2K4	P45985	MAP2K4	T56	R58S	58	Missense	proximal	2	no	0.005	0.006	EPSD	TCGA;COSMIC	0.006	Gain
STE_STE7_MEK4_MAP2K4_ST	P45985	MAP2K4	P45985	MAP2K4	S80	S80N	80	Missense	central	0	yes	0.006	0.000	EPSD	TCGA;COSMIC	0.006	Loss
STE_STE7_MEK4_MAP2K4_ST	P45985	MAP2K4	P45985	MAP2K4	S80	S83A	83	Missense	distal	3	no	0.006	0.005	EPSD	TCGA	0.006	Loss
STE_STE7_MEK4_MAP2K4_ST	P45985	MAP2K4	P45985	MAP2K4	S90	S83A	83	Missense	distal	-7	no	0.006	0.007	EPSD	TCGA	0.006	Up-regulation
STE_STE7_MEK4_MAP2K4_ST	P45985	MAP2K4	P45985	MAP2K4	S90	S90F	90	Missense	central	0	yes	0.006	0.000	EPSD	TCGA;COSMIC	0.006	Loss
STE_STE7_MEK4_MAP2K4_ST	P45985	MAP2K4	P45985	MAP2K4	S257	S257F	257	Missense	central	0	yes	0.019	0.000	PhosphoSitePlus;EPSD	TCGA;COSMIC	0.006	Loss
STE_STE7_MEK4_MAP2K4_ST	P45985	MAP2K4	P45985	MAP2K4	T261	G265C	265	Missense	distal	4	no	0.013	0.012	EPSD;PhosphoSitePlus	TCGA;COSMIC	0.006	Down-regulation
AGC_PDK1_PDPK1_ST	Q9HBY8	SGK2	O15530	PDPK1	S64	S63P	63	Missense	proximal	-1	no	6.464	6.444	EPSD	TCGA;COSMIC	3.516	Down-regulation
AGC_PDK1_PDPK1_ST	Q9HBY8	SGK2	O15530	PDPK1	S64	S63C	63	Missense	proximal	-1	no	6.464	6.157	EPSD	TCGA;COSMIC	3.516	Down-regulation
AGC_PDK1_PDPK1_ST	Q9HBY8	SGK2	O15530	PDPK1	S64	M61I	61	Missense	distal	-3	no	6.464	5.332	EPSD	TCGA;COSMIC	3.516	Down-regulation
AGC_PDK1_PDPK1_ST	Q9HBY8	SGK2	O15530	PDPK1	S64	S63Y	63	Missense	proximal	-1	no	6.464	6.197	EPSD	TCGA	3.516	Down-regulation
AGC_PDK1_PDPK1_ST	Q9HBY8	SGK2	O15530	PDPK1	S70	S63P	63	Missense	distal	-7	no	4.284	4.310	EPSD	TCGA;COSMIC	3.516	Up-regulation
AGC_PDK1_PDPK1_ST	Q9HBY8	SGK2	O15530	PDPK1	S70	S63C	63	Missense	distal	-7	no	4.284	3.346	EPSD	TCGA;COSMIC	3.516	Loss
AGC_PDK1_PDPK1_ST	Q9HBY8	SGK2	O15530	PDPK1	S70	S63Y	63	Missense	distal	-7	no	4.284	3.421	EPSD	TCGA	3.516	Loss
AGC_PDK1_PDPK1_ST	O15530	PDPK1	O15530	PDPK1	S92	L88F	88	Missense	distal	-4	no	5.413	5.507	EPSD	TCGA;ICGC;COSMIC	3.516	Up-regulation
AGC_PDK1_PDPK1_ST	O15530	PDPK1	O15530	PDPK1	S92	T95M	95	Missense	distal	3	no	5.413	5.536	EPSD	TCGA;COSMIC	3.516	Up-regulation
AGC_PDK1_PDPK1_ST	O15530	PDPK1	O15530	PDPK1	S250	V249I	249	Missense	proximal	-1	no	5.053	4.723	EPSD	TCGA;COSMIC	3.516	Down-regulation
AGC_PDK1_PDPK1_ST	O15530	PDPK1	O15530	PDPK1	S393	S400Y	400	Missense	distal	7	no	5.190	5.171	PhosphoSitePlus;EPSD	TCGA;COSMIC	3.516	Down-regulation
AGC_PDK1_PDPK1_ST	O15530	PDPK1	O15530	PDPK1	S393	Q387P	387	Missense	distal	-6	no	5.190	5.172	PhosphoSitePlus;EPSD	TCGA;COSMIC	3.516	Down-regulation
AGC_PDK1_PDPK1_ST	O15530	PDPK1	O15530	PDPK1	S393	S390L	390	Missense	distal	-3	no	5.190	4.404	PhosphoSitePlus;EPSD	TCGA;COSMIC	3.516	Down-regulation
AGC_PDK1_PDPK1_ST	O15530	PDPK1	O15530	PDPK1	S396	S400Y	400	Missense	distal	4	no	5.565	4.701	EPSD;PhosphoSitePlus	TCGA;COSMIC	3.516	Down-regulation
AGC_PDK1_PDPK1_ST	O15530	PDPK1	O15530	PDPK1	S396	S390L	390	Missense	distal	-6	no	5.565	5.657	EPSD;PhosphoSitePlus	TCGA;COSMIC	3.516	Up-regulation
AGC_PDK1_PDPK1_ST	O15530	PDPK1	O15530	PDPK1	S410	G409S	409	Missense	proximal	-1	no	4.858	4.893	EPSD;PhosphoSitePlus	TCGA;COSMIC	3.516	Up-regulation
AGC_PDK1_PDPK1_ST	O15530	PDPK1	O15530	PDPK1	T513	F514L	514	Missense	proximal	1	no	5.407	2.446	EPSD;PhosphoSitePlus	TCGA;COSMIC	3.516	Loss
AGC_PDK1_PDPK1_ST	O15530	PDPK1	O15530	PDPK1	T513	E507A	507	Missense	distal	-6	no	5.407	5.382	EPSD;PhosphoSitePlus	TCGA;COSMIC	3.516	Down-regulation
AGC_PDK1_PDPK1_ST	Q16512	PKN1	O15530	PDPK1	S566	S573L	573	Missense	distal	7	no	3.532	3.129	EPSD	TCGA;COSMIC	3.516	Loss
AGC_PDK1_PDPK1_ST	Q16512	PKN1	O15530	PDPK1	S573	S573L	573	Missense	central	0	yes	7.194	0.000	EPSD	TCGA;COSMIC	3.516	Loss
AGC_PDK1_PDPK1_ST	Q16512	PKN1	O15530	PDPK1	S575	S573L	573	Missense	proximal	-2	no	4.264	4.091	EPSD	TCGA;COSMIC	3.516	Down-regulation
AGC_PDK1_PDPK1_ST	Q16512	PKN1	O15530	PDPK1	S579	S573L	573	Missense	distal	-6	no	5.212	5.303	EPSD	TCGA;COSMIC	3.516	Up-regulation
AGC_PDK1_PDPK1_ST	Q99814	EPAS1	O15530	PDPK1	T324	R330C	330	Missense	distal	6	no	5.953	5.954	PhosphoSitePlus	TCGA;ICGC;COSMIC	3.516	Up-regulation
AGC_PDK1_PDPK1_ST	Q99814	EPAS1	O15530	PDPK1	T324	T321A	321	Missense	distal	-3	no	5.953	5.368	PhosphoSitePlus	TCGA;ICGC	3.516	Down-regulation
AGC_PDK1_PDPK1_ST	Q99814	EPAS1	O15530	PDPK1	S672	H675Y	675	Missense	distal	3	no	7.070	6.762	EPSD	TCGA;ICGC;COSMIC	3.516	Down-regulation
AGC_PDK1_PDPK1_ST	Q99814	EPAS1	O15530	PDPK1	S672	L667F	667	Missense	distal	-5	no	7.070	7.154	EPSD	TCGA;ICGC;COSMIC	3.516	Up-regulation
AGC_PDK1_PDPK1_ST	Q99814	EPAS1	O15530	PDPK1	S677	A684T	684	Missense	distal	7	no	4.508	4.734	EPSD	TCGA;ICGC	3.516	Up-regulation
AGC_PDK1_PDPK1_ST	Q99814	EPAS1	O15530	PDPK1	S677	H675Y	675	Missense	proximal	-2	no	4.508	4.441	EPSD	TCGA;ICGC;COSMIC	3.516	Down-regulation
AGC_PDK1_PDPK1_ST	Q99814	EPAS1	O15530	PDPK1	S677	R682M	682	Missense	distal	5	no	4.508	4.831	EPSD	TCGA;ICGC;COSMIC	3.516	Up-regulation
AGC_PDK1_PDPK1_ST	Q99814	EPAS1	O15530	PDPK1	S677	K680N	680	Missense	distal	3	no	4.508	4.584	EPSD	TCGA;ICGC	3.516	Up-regulation
AGC_PDK1_PDPK1_ST	Q99814	EPAS1	O15530	PDPK1	T678	A684T	684	Missense	distal	6	no	4.790	4.789	EPSD	TCGA;ICGC	3.516	Down-regulation
AGC_PDK1_PDPK1_ST	Q99814	EPAS1	O15530	PDPK1	T678	H675Y	675	Missense	distal	-3	no	4.790	4.470	EPSD	TCGA;ICGC;COSMIC	3.516	Down-regulation
AGC_PDK1_PDPK1_ST	Q99814	EPAS1	O15530	PDPK1	T678	R682M	682	Missense	distal	4	no	4.790	4.616	EPSD	TCGA;ICGC;COSMIC	3.516	Down-regulation
AGC_PDK1_PDPK1_ST	Q99814	EPAS1	O15530	PDPK1	T678	K680N	680	Missense	proximal	2	no	4.790	4.845	EPSD	TCGA;ICGC	3.516	Up-regulation
AGC_PDK1_PDPK1_ST	Q99814	EPAS1	O15530	PDPK1	S696	R690Q	690	Missense	distal	-6	no	3.601	3.611	EPSD	TCGA;ICGC;COSMIC	3.516	Up-regulation
AGC_PDK1_PDPK1_ST	Q99814	EPAS1	O15530	PDPK1	S696	V694M	694	Missense	proximal	-2	no	3.601	3.647	EPSD	TCGA;ICGC;COSMIC	3.516	Up-regulation
AGC_PDK1_PDPK1_ST	Q99814	EPAS1	O15530	PDPK1	S830	R825W	825	Missense	distal	-5	no	5.177	5.318	EPSD	TCGA;ICGC;COSMIC	3.516	Up-regulation
AGC_PDK1_PDPK1_ST	Q99814	EPAS1	O15530	PDPK1	S830	S830L	830	Missense	central	0	yes	5.177	0.000	EPSD	TCGA;COSMIC	3.516	Loss
AGC_PDK1_PDPK1_ST	Q99814	EPAS1	O15530	PDPK1	S830	Y834C	834	Missense	distal	4	no	5.177	4.921	EPSD	TCGA;ICGC;COSMIC	3.516	Down-regulation
AGC_PDK1_PDPK1_ST	P08559	PDHA1	O15530	PDPK1	S232	A236D	236	Missense	distal	4	no	4.854	4.231	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	3.516	Down-regulation
AGC_PDK1_PDPK1_ST	P31751	AKT2	O15530	PDPK1	T72	R69Q	69	Missense	distal	-3	no	5.529	4.795	EPSD	TCGA;ICGC;COSMIC	3.516	Down-regulation
AGC_PDK1_PDPK1_ST	P31751	AKT2	O15530	PDPK1	S126	M120I	120	Missense	distal	-6	no	6.928	7.065	EPSD	TCGA;ICGC	3.516	Up-regulation
AGC_PDK1_PDPK1_ST	P31751	AKT2	O15530	PDPK1	T309	E315D	315	Missense	distal	6	no	10.762	10.761	PhosphoSitePlus	TCGA;ICGC;COSMIC	3.516	Down-regulation
AGC_PDK1_PDPK1_ST	P31751	AKT2	O15530	PDPK1	T451	Q446H	446	Missense	distal	-5	no	5.456	5.470	EPSD	TCGA;COSMIC	3.516	Up-regulation
AGC_PDK1_PDPK1_ST	P31751	AKT2	O15530	PDPK1	T451	D454G	454	Missense	distal	3	no	5.456	5.665	EPSD	TCGA;COSMIC	3.516	Up-regulation
AGC_PDK1_PDPK1_ST	P31751	AKT2	O15530	PDPK1	T451	S447F	447	Missense	distal	-4	no	5.456	5.619	EPSD	TCGA;COSMIC	3.516	Up-regulation
AGC_PDK1_PDPK1_ST	P31751	AKT2	O15530	PDPK1	S474	P471S	471	Missense	distal	-3	no	3.538	3.865	EPSD	TCGA;ICGC;COSMIC	3.516	Up-regulation
AGC_PDK1_PDPK1_ST	P31751	AKT2	O15530	PDPK1	S474	R480C	480	Missense	distal	6	no	3.538	3.539	EPSD	TCGA;ICGC;COSMIC	3.516	Up-regulation
AGC_PDK1_PDPK1_ST	P31751	AKT2	O15530	PDPK1	S474	S474F	474	Missense	central	0	yes	3.538	0.000	EPSD	TCGA;ICGC;COSMIC	3.516	Loss
AGC_PDK1_PDPK1_ST	P05106	ITGB3	O15530	PDPK1	S110	P111H	111	Missense	proximal	1	no	6.532	2.356	EPSD	TCGA;ICGC;COSMIC	3.516	Loss
AGC_PDK1_PDPK1_ST	P05106	ITGB3	O15530	PDPK1	S110	Q108R	108	Missense	proximal	-2	no	6.532	6.592	EPSD	TCGA;ICGC;COSMIC	3.516	Up-regulation
AGC_PDK1_PDPK1_ST	P05106	ITGB3	O15530	PDPK1	T779	T784M	784	Missense	distal	5	no	4.971	4.717	PhosphoSitePlus	TCGA;ICGC;COSMIC	3.516	Down-regulation
AGC_PDK1_PDPK1_ST	P05106	ITGB3	O15530	PDPK1	T779	Y773H	773	Missense	distal	-6	no	4.971	4.931	PhosphoSitePlus	TCGA;ICGC;COSMIC	3.516	Down-regulation
AGC_PDK1_PDPK1_ST	P05106	ITGB3	O15530	PDPK1	T779	R786Q	786	Missense	distal	7	no	4.971	4.863	PhosphoSitePlus	TCGA;ICGC;COSMIC	3.516	Down-regulation
AGC_PDK1_PDPK1_ST	P05106	ITGB3	O15530	PDPK1	T779	S778C	778	Missense	proximal	-1	no	4.971	4.665	PhosphoSitePlus	TCGA;ICGC;COSMIC	3.516	Down-regulation
AGC_PDK1_PDPK1_ST	P05106	ITGB3	O15530	PDPK1	T784	T784M	784	Missense	central	0	yes	4.331	0.000	EPSD	TCGA;ICGC;COSMIC	3.516	Loss
AGC_PDK1_PDPK1_ST	P05106	ITGB3	O15530	PDPK1	T784	R786Q	786	Missense	proximal	2	no	4.331	4.274	EPSD	TCGA;ICGC;COSMIC	3.516	Down-regulation
AGC_PDK1_PDPK1_ST	P05106	ITGB3	O15530	PDPK1	T784	S778C	778	Missense	distal	-6	no	4.331	4.398	EPSD	TCGA;ICGC;COSMIC	3.516	Up-regulation
AGC_PDK1_PDPK1_ST	P23443	RPS6KB1	O15530	PDPK1	T252	H251Y	251	Missense	proximal	-1	no	7.479	7.197	EPSD;PhosphoSitePlus	TCGA;COSMIC	3.516	Down-regulation
AGC_PDK1_PDPK1_ST	P23443	RPS6KB1	O15530	PDPK1	T390	Q389E	389	Missense	proximal	-1	no	5.496	5.375	EPSD	TCGA;COSMIC	3.516	Down-regulation
AGC_PDK1_PDPK1_ST	P23443	RPS6KB1	O15530	PDPK1	S394	Q389E	389	Missense	distal	-5	no	5.823	5.849	PhosphoSitePlus;EPSD	TCGA;COSMIC	3.516	Up-regulation
AGC_PDK1_PDPK1_ST	Q05513	PRKCZ	O15530	PDPK1	T410	G405C	405	Missense	distal	-5	no	12.101	12.309	PhosphoSitePlus	TCGA	3.516	Up-regulation
AGC_PDK1_PDPK1_ST	Q05513	PRKCZ	O15530	PDPK1	T410	P415L	415	Missense	distal	5	no	12.101	11.107	PhosphoSitePlus	TCGA	3.516	Down-regulation
AGC_PDK1_PDPK1_ST	Q05513	PRKCZ	O15530	PDPK1	T410	T408M	408	Missense	proximal	-2	no	12.101	12.039	PhosphoSitePlus	TCGA	3.516	Down-regulation
AGC_PDK1_PDPK1_ST	Q05513	PRKCZ	O15530	PDPK1	T414	E421K	421	Missense	distal	7	no	3.651	3.610	EPSD	TCGA	3.516	Down-regulation
AGC_PDK1_PDPK1_ST	Q05513	PRKCZ	O15530	PDPK1	T414	P415L	415	Missense	proximal	1	no	3.651	1.232	EPSD	TCGA	3.516	Loss
AGC_PDK1_PDPK1_ST	Q05513	PRKCZ	O15530	PDPK1	T414	T408M	408	Missense	distal	-6	no	3.651	3.644	EPSD	TCGA	3.516	Down-regulation
AGC_PDK1_PDPK1_ST	Q05513	PRKCZ	O15530	PDPK1	T560	D563N	563	Missense	distal	3	no	4.759	4.802	EPSD	TCGA	3.516	Up-regulation
AGC_PDK1_PDPK1_ST	Q05513	PRKCZ	O15530	PDPK1	T560	V557M	557	Missense	distal	-3	no	4.759	4.969	EPSD	TCGA	3.516	Up-regulation
AGC_PDK1_PDPK1_ST	P17612	PRKACA	O15530	PDPK1	S54	G56R	56	Missense	proximal	2	no	6.069	6.110	EPSD	TCGA;ICGC;COSMIC	3.516	Up-regulation
AGC_PDK1_PDPK1_ST	P17612	PRKACA	O15530	PDPK1	S110	V105I	105	Missense	distal	-5	no	3.366	3.549	EPSD	TCGA;ICGC;COSMIC	3.516	Gain
AGC_PDK1_PDPK1_ST	P17612	PRKACA	O15530	PDPK1	S110	F109L	109	Missense	proximal	-1	no	3.366	3.578	EPSD	TCGA;ICGC;COSMIC	3.516	Gain
AGC_PDK1_PDPK1_ST	P17612	PRKACA	O15530	PDPK1	T198	W197R	197	Missense	proximal	-1	no	5.939	6.175	PhosphoSitePlus	TCGA;ICGC;COSMIC	3.516	Up-regulation
AGC_PDK1_PDPK1_ST	P17612	PRKACA	O15530	PDPK1	T198	W197G	197	Missense	proximal	-1	no	5.939	6.202	PhosphoSitePlus	TCGA;ICGC;COSMIC	3.516	Up-regulation
AGC_PDK1_PDPK1_ST	P17612	PRKACA	O15530	PDPK1	T198	W197L	197	Missense	proximal	-1	no	5.939	5.840	PhosphoSitePlus	TCGA;ICGC;COSMIC	3.516	Down-regulation
AGC_PDK1_PDPK1_ST	P17612	PRKACA	O15530	PDPK1	T198	R191C	191	Missense	distal	-7	no	5.939	5.215	PhosphoSitePlus	TCGA;ICGC;COSMIC	3.516	Down-regulation
AGC_PDK1_PDPK1_ST	P17612	PRKACA	O15530	PDPK1	T198	G201S	201	Missense	distal	3	no	5.939	5.850	PhosphoSitePlus	TCGA;ICGC;COSMIC	3.516	Down-regulation
AGC_PDK1_PDPK1_ST	P31749	AKT1	O15530	PDPK1	T72	T65M	65	Missense	distal	-7	no	5.536	5.541	EPSD	TCGA;ICGC;COSMIC	3.516	Up-regulation
AGC_PDK1_PDPK1_ST	P31749	AKT1	O15530	PDPK1	T72	R69W	69	Missense	distal	-3	no	5.536	4.775	EPSD	TCGA;ICGC;COSMIC	3.516	Down-regulation
AGC_PDK1_PDPK1_ST	P31749	AKT1	O15530	PDPK1	T72	Q79K	79	Missense	distal	7	no	5.536	5.336	EPSD	TCGA;ICGC;COSMIC	3.516	Down-regulation
AGC_PDK1_PDPK1_ST	P31749	AKT1	O15530	PDPK1	T87	W80R	80	Missense	distal	-7	no	3.040	3.814	EPSD	TCGA;ICGC;COSMIC	3.516	Gain
AGC_PDK1_PDPK1_ST	P31749	AKT1	O15530	PDPK1	S124	R121W	121	Missense	distal	-3	no	6.247	5.485	EPSD	TCGA;ICGC;COSMIC	3.516	Down-regulation
AGC_PDK1_PDPK1_ST	P31749	AKT1	O15530	PDPK1	S124	A131T	131	Missense	distal	7	no	6.247	6.472	EPSD	TCGA;ICGC;COSMIC	3.516	Up-regulation
AGC_PDK1_PDPK1_ST	P31749	AKT1	O15530	PDPK1	S137	E132K	132	Missense	distal	-5	no	3.627	3.680	EPSD	TCGA;COSMIC	3.516	Up-regulation
AGC_PDK1_PDPK1_ST	P31749	AKT1	O15530	PDPK1	S137	E133D	133	Missense	distal	-4	no	3.627	3.612	EPSD	TCGA;ICGC;COSMIC	3.516	Down-regulation
AGC_PDK1_PDPK1_ST	P31749	AKT1	O15530	PDPK1	S137	A131T	131	Missense	distal	-6	no	3.627	3.603	EPSD	TCGA;ICGC;COSMIC	3.516	Down-regulation
AGC_PDK1_PDPK1_ST	P31749	AKT1	O15530	PDPK1	T308	G311D	311	Missense	distal	3	no	10.175	9.966	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC;GDSC;CCLE	3.516	Down-regulation
AGC_PDK1_PDPK1_ST	P31749	AKT1	O15530	PDPK1	T450	I447V	447	Missense	distal	-3	no	5.080	6.002	EPSD	TCGA;ICGC;COSMIC	3.516	Up-regulation
AGC_PDK1_PDPK1_ST	P31749	AKT1	O15530	PDPK1	S473	S475L	475	Missense	proximal	2	no	5.258	5.173	PhosphoSitePlus;EPSD	TCGA;ICGC;COSMIC	3.516	Down-regulation
AGC_PDK1_PDPK1_ST	O60331	PIP5K1C	O15530	PDPK1	T69	K72R	72	Missense	distal	3	no	4.887	4.826	EPSD	TCGA;ICGC;COSMIC	3.516	Down-regulation
AGC_PDK1_PDPK1_ST	O60331	PIP5K1C	O15530	PDPK1	T69	G62C	62	Missense	distal	-7	no	4.887	3.966	EPSD	TCGA;ICGC;COSMIC	3.516	Down-regulation
AGC_PDK1_PDPK1_ST	O60331	PIP5K1C	O15530	PDPK1	T69	G67C	67	Missense	proximal	-2	no	4.887	4.788	EPSD	TCGA;ICGC;COSMIC	3.516	Down-regulation
AGC_PDK1_PDPK1_ST	O60331	PIP5K1C	O15530	PDPK1	T70	K72R	72	Missense	proximal	2	no	3.767	3.840	EPSD	TCGA;ICGC;COSMIC	3.516	Up-regulation
AGC_PDK1_PDPK1_ST	O60331	PIP5K1C	O15530	PDPK1	T70	G67C	67	Missense	distal	-3	no	3.767	3.641	EPSD	TCGA;ICGC;COSMIC	3.516	Down-regulation
AGC_PDK1_PDPK1_ST	O60331	PIP5K1C	O15530	PDPK1	S95	V91M	91	Missense	distal	-4	no	3.944	3.875	EPSD	TCGA;ICGC;COSMIC	3.516	Down-regulation
AGC_PDK1_PDPK1_ST	O60331	PIP5K1C	O15530	PDPK1	S424	P428H	428	Missense	distal	4	no	3.581	3.087	EPSD	TCGA;ICGC;COSMIC	3.516	Loss
AGC_PDK1_PDPK1_ST	O60331	PIP5K1C	O15530	PDPK1	S424	D419N	419	Missense	distal	-5	no	3.581	3.496	EPSD	TCGA;ICGC	3.516	Loss
AGC_PDK1_PDPK1_ST	O60331	PIP5K1C	O15530	PDPK1	T442	R445W	445	Missense	distal	3	no	3.610	3.506	EPSD	TCGA;ICGC;COSMIC	3.516	Loss
AGC_PDK1_PDPK1_ST	O60331	PIP5K1C	O15530	PDPK1	S448	R445W	445	Missense	distal	-3	no	4.948	4.186	PhosphoSitePlus	TCGA;ICGC;COSMIC	3.516	Down-regulation
AGC_PDK1_PDPK1_ST	O60331	PIP5K1C	O15530	PDPK1	S515	C511Y	511	Missense	distal	-4	no	6.523	6.514	EPSD	TCGA;ICGC;COSMIC	3.516	Down-regulation
AGC_PDK1_PDPK1_ST	O60331	PIP5K1C	O15530	PDPK1	T526	A525T	525	Missense	proximal	-1	no	4.696	4.851	EPSD	TCGA;ICGC	3.516	Up-regulation
AGC_PDK1_PDPK1_ST	O60331	PIP5K1C	O15530	PDPK1	T526	S530F	530	Missense	distal	4	no	4.696	3.167	EPSD	TCGA;ICGC;COSMIC	3.516	Loss
AGC_PDK1_PDPK1_ST	O60331	PIP5K1C	O15530	PDPK1	T526	T526M	526	Missense	central	0	yes	4.696	0.000	EPSD	TCGA;ICGC	3.516	Loss
AGC_PDK1_PDPK1_ST	O60331	PIP5K1C	O15530	PDPK1	S529	S530F	530	Missense	proximal	1	no	3.318	6.654	EPSD	TCGA;ICGC;COSMIC	3.516	Gain
AGC_PDK1_PDPK1_ST	O60331	PIP5K1C	O15530	PDPK1	S539	S541L	541	Missense	proximal	2	no	6.158	6.073	EPSD	TCGA;ICGC;COSMIC	3.516	Down-regulation
AGC_PDK1_PDPK1_ST	O60331	PIP5K1C	O15530	PDPK1	S539	S534F	534	Missense	distal	-5	no	6.158	6.527	EPSD	TCGA;ICGC;COSMIC	3.516	Up-regulation
AGC_PDK1_PDPK1_ST	O60331	PIP5K1C	O15530	PDPK1	S539	P540S	540	Missense	proximal	1	no	6.158	3.364	EPSD	TCGA;ICGC;COSMIC	3.516	Loss
AGC_PDK1_PDPK1_ST	O60331	PIP5K1C	O15530	PDPK1	S539	R538Q	538	Missense	proximal	-1	no	6.158	6.141	EPSD	TCGA;ICGC;COSMIC	3.516	Down-regulation
AGC_PDK1_PDPK1_ST	O60331	PIP5K1C	O15530	PDPK1	S539	R538W	538	Missense	proximal	-1	no	6.158	5.922	EPSD	TCGA;ICGC	3.516	Down-regulation
AGC_PDK1_PDPK1_ST	O60331	PIP5K1C	O15530	PDPK1	T543	S541L	541	Missense	proximal	-2	no	3.666	3.493	EPSD	TCGA;ICGC;COSMIC	3.516	Loss
AGC_PDK1_PDPK1_ST	O60331	PIP5K1C	O15530	PDPK1	T543	R548W	548	Missense	distal	5	no	3.666	2.906	EPSD	TCGA;ICGC;COSMIC	3.516	Loss
AGC_PDK1_PDPK1_ST	O60331	PIP5K1C	O15530	PDPK1	T543	R548Q	548	Missense	distal	5	no	3.666	3.249	EPSD	TCGA;ICGC	3.516	Loss
AGC_PDK1_PDPK1_ST	O60331	PIP5K1C	O15530	PDPK1	T543	P540S	540	Missense	distal	-3	no	3.666	3.994	EPSD	TCGA;ICGC;COSMIC	3.516	Up-regulation
AGC_PDK1_PDPK1_ST	O60331	PIP5K1C	O15530	PDPK1	T543	R538Q	538	Missense	distal	-5	no	3.666	3.646	EPSD	TCGA;ICGC;COSMIC	3.516	Down-regulation
AGC_PDK1_PDPK1_ST	O60331	PIP5K1C	O15530	PDPK1	T543	R538W	538	Missense	distal	-5	no	3.666	3.808	EPSD	TCGA;ICGC	3.516	Up-regulation
AGC_PDK1_PDPK1_ST	O60331	PIP5K1C	O15530	PDPK1	S650	D643N	643	Missense	distal	-7	no	4.892	5.269	EPSD	TCGA;ICGC	3.516	Up-regulation
AGC_PDK1_PDPK1_ST	O60331	PIP5K1C	O15530	PDPK1	S650	E644D	644	Missense	distal	-6	no	4.892	4.897	EPSD	TCGA;ICGC;COSMIC	3.516	Up-regulation
AGC_PDK1_PDPK1_ST	O60331	PIP5K1C	O15530	PDPK1	S650	Y654C	654	Missense	distal	4	no	4.892	4.636	EPSD	TCGA;ICGC;COSMIC	3.516	Down-regulation
AGC_PDK1_PDPK1_ST	O60331	PIP5K1C	O15530	PDPK1	S650	H653Y	653	Missense	distal	3	no	4.892	4.583	EPSD	TCGA;ICGC;COSMIC	3.516	Down-regulation
AGC_PDK1_PDPK1_ST	O60331	PIP5K1C	O15530	PDPK1	S650	Y649H	649	Missense	proximal	-1	no	4.892	5.173	EPSD	TCGA;ICGC;COSMIC	3.516	Up-regulation
AGC_PDK1_PDPK1_ST	O60331	PIP5K1C	O15530	PDPK1	S650	S646C	646	Missense	distal	-4	no	4.892	4.966	EPSD	TCGA;ICGC;COSMIC	3.516	Up-regulation
AGC_PDK1_PDPK1_ST	O60331	PIP5K1C	O15530	PDPK1	S655	A656V	656	Missense	proximal	1	no	1.463	4.183	EPSD	TCGA;ICGC;COSMIC;CCLE	3.516	Gain
AGC_PDK1_PDPK1_ST	Q02750	MAP2K1	O15530	PDPK1	S24	N21T	21	Missense	distal	-3	no	3.426	3.967	EPSD	TCGA	3.516	Gain
AGC_PDK1_PDPK1_ST	Q02750	MAP2K1	O15530	PDPK1	S24	E31V	31	Missense	distal	7	no	3.426	3.635	EPSD	TCGA;ICGC	3.516	Gain
AGC_PDK1_PDPK1_ST	Q02750	MAP2K1	O15530	PDPK1	S222	V224M	224	Missense	proximal	2	no	8.613	8.656	PhosphoSitePlus	TCGA;ICGC;COSMIC	3.516	Up-regulation
AGC_PDK1_PDPK1_ST	Q02750	MAP2K1	O15530	PDPK1	S222	R227K	227	Missense	distal	5	no	8.613	8.061	PhosphoSitePlus	TCGA;ICGC;COSMIC	3.516	Down-regulation
AGC_PDK1_PDPK1_ST	Q02750	MAP2K1	O15530	PDPK1	S231	L235H	235	Missense	distal	4	no	4.679	4.933	EPSD	TCGA;ICGC;COSMIC	3.516	Up-regulation
AGC_PDK1_PDPK1_ST	Q02750	MAP2K1	O15530	PDPK1	S231	S231L	231	Missense	central	0	yes	4.679	0.000	EPSD	TCGA;ICGC;COSMIC	3.516	Loss
AGC_PDK1_PDPK1_ST	Q02750	MAP2K1	O15530	PDPK1	S231	V224M	224	Missense	distal	-7	no	4.679	5.097	EPSD	TCGA;ICGC;COSMIC	3.516	Up-regulation
AGC_PDK1_PDPK1_ST	Q02750	MAP2K1	O15530	PDPK1	S231	R227K	227	Missense	distal	-4	no	4.679	4.717	EPSD	TCGA;ICGC;COSMIC	3.516	Up-regulation
AGC_PDK1_PDPK1_ST	Q02750	MAP2K1	O15530	PDPK1	T286	P290S	290	Missense	distal	4	no	3.876	4.017	EPSD	TCGA;ICGC	3.516	Up-regulation
AGC_PDK1_PDPK1_ST	Q02750	MAP2K1	O15530	PDPK1	T292	G294R	294	Missense	proximal	2	no	5.026	5.067	EPSD	TCGA;ICGC;COSMIC	3.516	Up-regulation
AGC_PDK1_PDPK1_ST	Q02750	MAP2K1	O15530	PDPK1	T292	G294V	294	Missense	proximal	2	no	5.026	5.061	EPSD	TCGA;ICGC;COSMIC	3.516	Up-regulation
AGC_PDK1_PDPK1_ST	Q02750	MAP2K1	O15530	PDPK1	T292	G294E	294	Missense	proximal	2	no	5.026	5.013	EPSD	TCGA;ICGC;COSMIC	3.516	Down-regulation
AGC_PDK1_PDPK1_ST	Q02750	MAP2K1	O15530	PDPK1	T292	P290S	290	Missense	proximal	-2	no	5.026	5.031	EPSD	TCGA;ICGC	3.516	Up-regulation
AGC_PDK1_PDPK1_ST	Q02750	MAP2K1	O15530	PDPK1	S299	G294R	294	Missense	distal	-5	no	3.809	3.892	EPSD	TCGA;ICGC;COSMIC	3.516	Up-regulation
AGC_PDK1_PDPK1_ST	Q02750	MAP2K1	O15530	PDPK1	S299	G294V	294	Missense	distal	-5	no	3.809	3.954	EPSD	TCGA;ICGC;COSMIC	3.516	Up-regulation
AGC_PDK1_PDPK1_ST	Q02750	MAP2K1	O15530	PDPK1	S299	G294E	294	Missense	distal	-5	no	3.809	3.898	EPSD	TCGA;ICGC;COSMIC	3.516	Up-regulation
AGC_PDK1_PDPK1_ST	Q02750	MAP2K1	O15530	PDPK1	S299	D303N	303	Missense	distal	4	no	3.809	4.252	EPSD	TCGA;ICGC;COSMIC	3.516	Up-regulation
AGC_PDK1_PDPK1_ST	Q96BR1	SGK3	O15530	PDPK1	S121	D120N	120	Missense	proximal	-1	no	4.864	5.061	EPSD	TCGA;ICGC;COSMIC	3.516	Up-regulation
AGC_PDK1_PDPK1_ST	Q96BR1	SGK3	O15530	PDPK1	S121	A115S	115	Missense	distal	-6	no	4.864	4.847	EPSD	TCGA;ICGC;COSMIC	3.516	Down-regulation
AGC_PDK1_PDPK1_ST	Q96BR1	SGK3	O15530	PDPK1	S142	S142C	142	Missense	central	0	yes	3.577	0.000	EPSD	TCGA;ICGC;COSMIC	3.516	Loss
AGC_PDK1_PDPK1_ST	Q96BR1	SGK3	O15530	PDPK1	S142	S137Y	137	Missense	distal	-5	no	3.577	3.786	EPSD	TCGA;ICGC;COSMIC	3.516	Up-regulation
AGC_PDK1_PDPK1_ST	Q96BR1	SGK3	O15530	PDPK1	T320	Y327C	327	Missense	distal	7	no	11.046	10.729	PhosphoSitePlus	TCGA;ICGC;COSMIC	3.516	Down-regulation
AGC_PDK1_PDPK1_ST	Q9Y243	AKT3	O15530	PDPK1	T305	P310A	310	Missense	distal	5	no	10.850	10.539	PhosphoSitePlus	TCGA;ICGC;COSMIC	3.516	Down-regulation
AGC_PDK1_PDPK1_ST	Q9Y243	AKT3	O15530	PDPK1	T305	A300T	300	Missense	distal	-5	no	10.850	10.869	PhosphoSitePlus	TCGA;ICGC;COSMIC	3.516	Up-regulation
AGC_PDK1_PDPK1_ST	Q9Y243	AKT3	O15530	PDPK1	T305	A301D	301	Missense	distal	-4	no	10.850	10.861	PhosphoSitePlus	TCGA;ICGC;COSMIC	3.516	Up-regulation
AGC_PDK1_PDPK1_ST	Q9Y243	AKT3	O15530	PDPK1	T305	G308C	308	Missense	distal	3	no	10.850	10.445	PhosphoSitePlus	TCGA;ICGC;COSMIC	3.516	Down-regulation
AGC_PDK1_PDPK1_ST	Q9Y243	AKT3	O15530	PDPK1	T447	P449S	449	Missense	proximal	2	no	4.706	4.753	EPSD	TCGA;ICGC;COSMIC	3.516	Up-regulation
AGC_PDK1_PDPK1_ST	Q9Y243	AKT3	O15530	PDPK1	T447	K451T	451	Missense	distal	4	no	4.706	5.680	EPSD	TCGA;ICGC;COSMIC	3.516	Up-regulation
AGC_PDK1_PDPK1_ST	Q9Y243	AKT3	O15530	PDPK1	T447	P448S	448	Missense	proximal	1	no	4.706	1.911	EPSD	TCGA;ICGC	3.516	Loss
AGC_PDK1_PDPK1_ST	Q9Y243	AKT3	O15530	PDPK1	S472	S474F	474	Missense	proximal	2	no	5.564	5.409	EPSD	TCGA;ICGC;COSMIC;GDSC;CCLE	3.516	Down-regulation
AGC_PDK1_PDPK1_ST	P36507	MAP2K2	O15530	PDPK1	S226	T230M	230	Missense	distal	4	no	8.691	8.126	PhosphoSitePlus	TCGA;ICGC;COSMIC	3.516	Down-regulation
AGC_PDK1_PDPK1_ST	P36507	MAP2K2	O15530	PDPK1	S226	V228M	228	Missense	proximal	2	no	8.691	8.734	PhosphoSitePlus	TCGA;ICGC;COSMIC	3.516	Up-regulation
AGC_PDK1_PDPK1_ST	P36507	MAP2K2	O15530	PDPK1	S295	S295L	295	Missense	central	0	yes	4.451	0.000	EPSD	TCGA;ICGC;COSMIC	3.516	Loss
AGC_PDK1_PDPK1_ST	P36507	MAP2K2	O15530	PDPK1	S295	P291L	291	Missense	distal	-4	no	4.451	4.562	EPSD	TCGA;ICGC;COSMIC	3.516	Up-regulation
AGC_PDK1_PDPK1_ST	P36507	MAP2K2	O15530	PDPK1	S295	P291S	291	Missense	distal	-4	no	4.451	4.494	EPSD	TCGA;ICGC;COSMIC	3.516	Up-regulation
AGC_PDK1_PDPK1_ST	P36507	MAP2K2	O15530	PDPK1	S295	H292R	292	Missense	distal	-3	no	4.451	4.931	EPSD	TCGA;ICGC;COSMIC	3.516	Up-regulation
AGC_PDK1_PDPK1_ST	P36507	MAP2K2	O15530	PDPK1	T394	A399V	399	Missense	distal	5	no	4.121	3.904	EPSD	TCGA;ICGC;COSMIC	3.516	Down-regulation
AGC_PDK1_PDPK1_ST	Q13153	PAK1	O15530	PDPK1	T167	E166V	166	Missense	proximal	-1	no	5.260	5.337	EPSD	TCGA;ICGC;COSMIC	3.516	Up-regulation
AGC_PDK1_PDPK1_ST	Q13153	PAK1	O15530	PDPK1	T167	E166D	166	Missense	proximal	-1	no	5.260	5.272	EPSD	TCGA;ICGC;COSMIC	3.516	Up-regulation
AGC_PDK1_PDPK1_ST	Q13153	PAK1	O15530	PDPK1	S220	N227S	227	Missense	distal	7	no	5.995	6.042	EPSD	TCGA;ICGC;COSMIC	3.516	Up-regulation
AGC_PDK1_PDPK1_ST	Q13153	PAK1	O15530	PDPK1	S223	N227S	227	Missense	distal	4	no	3.592	4.196	EPSD	TCGA;ICGC;COSMIC	3.516	Up-regulation
AGC_PDK1_PDPK1_ST	Q13153	PAK1	O15530	PDPK1	S223	T230I	230	Missense	distal	7	no	3.592	3.202	EPSD	TCGA;ICGC;COSMIC	3.516	Loss
AGC_PDK1_PDPK1_ST	Q13153	PAK1	O15530	PDPK1	S262	D265Y	265	Missense	distal	3	no	3.956	3.658	EPSD	TCGA;ICGC;COSMIC	3.516	Down-regulation
AGC_PDK1_PDPK1_ST	Q13153	PAK1	O15530	PDPK1	S262	G264C	264	Missense	proximal	2	no	3.956	3.922	EPSD	TCGA;ICGC;COSMIC	3.516	Down-regulation
AGC_PDK1_PDPK1_ST	Q13153	PAK1	O15530	PDPK1	T415	E417Q	417	Missense	proximal	2	no	3.666	3.663	EPSD	TCGA;ICGC;COSMIC	3.516	Down-regulation
AGC_PDK1_PDPK1_ST	Q13153	PAK1	O15530	PDPK1	T415	R421L	421	Missense	distal	6	no	3.666	3.668	EPSD	TCGA;ICGC;COSMIC	3.516	Up-regulation
AGC_PDK1_PDPK1_ST	Q13153	PAK1	O15530	PDPK1	T415	F410L	410	Missense	distal	-5	no	3.666	3.582	EPSD	TCGA;ICGC;COSMIC;GDSC;CCLE	3.516	Down-regulation
AGC_PDK1_PDPK1_ST	Q13153	PAK1	O15530	PDPK1	S422	E417Q	417	Missense	distal	-5	no	3.640	3.613	EPSD	TCGA;ICGC;COSMIC	3.516	Down-regulation
AGC_PDK1_PDPK1_ST	Q13153	PAK1	O15530	PDPK1	S422	R421L	421	Missense	proximal	-1	no	3.640	3.305	EPSD	TCGA;ICGC;COSMIC	3.516	Loss
AGC_PDK1_PDPK1_ST	Q13153	PAK1	O15530	PDPK1	T423	E417Q	417	Missense	distal	-6	no	6.335	6.314	PhosphoSitePlus	TCGA;ICGC;COSMIC	3.516	Down-regulation
AGC_PDK1_PDPK1_ST	Q13153	PAK1	O15530	PDPK1	T423	R421L	421	Missense	proximal	-2	no	6.335	6.211	PhosphoSitePlus	TCGA;ICGC;COSMIC	3.516	Down-regulation
AGC_PDK1_PDPK1_ST	Q13153	PAK1	O15530	PDPK1	T481	Y474C	474	Missense	distal	-7	no	5.140	5.065	EPSD	TCGA;ICGC	3.516	Down-regulation
AGC_PDK1_PDPK1_ST	Q13153	PAK1	O15530	PDPK1	T481	Y474H	474	Missense	distal	-7	no	5.140	5.660	EPSD	TCGA;ICGC	3.516	Up-regulation
AGC_PDK1_PDPK1_ST	Q13153	PAK1	O15530	PDPK1	T481	A477V	477	Missense	distal	-4	no	5.140	5.144	EPSD	TCGA;ICGC;COSMIC	3.516	Up-regulation
AGC_PDK1_PDPK1_ST	Q05655	PRKCD	O15530	PDPK1	S302	S299T	299	Missense	distal	-3	no	4.135	4.094	EPSD	TCGA;ICGC;COSMIC	3.516	Down-regulation
AGC_PDK1_PDPK1_ST	Q05655	PRKCD	O15530	PDPK1	S302	R300W	300	Missense	proximal	-2	no	4.135	4.028	EPSD	TCGA;ICGC;COSMIC	3.516	Down-regulation
AGC_PDK1_PDPK1_ST	Q05655	PRKCD	O15530	PDPK1	S302	S302L	302	Missense	central	0	yes	4.135	0.000	EPSD	TCGA;ICGC;COSMIC	3.516	Loss
AGC_PDK1_PDPK1_ST	Q05655	PRKCD	O15530	PDPK1	T451	E446K	446	Missense	distal	-5	no	4.677	4.730	EPSD	TCGA;ICGC;COSMIC	3.516	Up-regulation
AGC_PDK1_PDPK1_ST	Q05655	PRKCD	O15530	PDPK1	T451	F452L	452	Missense	proximal	1	no	4.677	1.716	EPSD	TCGA;ICGC;COSMIC	3.516	Loss
AGC_PDK1_PDPK1_ST	Q05655	PRKCD	O15530	PDPK1	T451	A454V	454	Missense	distal	3	no	4.677	4.541	EPSD	TCGA;ICGC;COSMIC	3.516	Down-regulation
AGC_PDK1_PDPK1_ST	Q05655	PRKCD	O15530	PDPK1	T451	R444H	444	Missense	distal	-7	no	4.677	4.547	EPSD	TCGA;ICGC;COSMIC	3.516	Down-regulation
AGC_PDK1_PDPK1_ST	Q05655	PRKCD	O15530	PDPK1	T507	C509R	509	Missense	proximal	2	no	9.430	9.504	PhosphoSitePlus	TCGA;ICGC;COSMIC	3.516	Up-regulation
AGC_PDK1_PDPK1_ST	Q05655	PRKCD	O15530	PDPK1	T507	T511N	511	Missense	distal	4	no	9.430	8.761	PhosphoSitePlus	TCGA;ICGC;COSMIC	3.516	Down-regulation
AGC_PDK1_PDPK1_ST	Q05655	PRKCD	O15530	PDPK1	S626	R628K	628	Missense	proximal	2	no	5.296	5.223	EPSD	TCGA;ICGC;COSMIC	3.516	Down-regulation
AGC_PDK1_PDPK1_ST	Q05655	PRKCD	O15530	PDPK1	S664	A659V	659	Missense	distal	-5	no	5.602	5.681	EPSD	TCGA;ICGC	3.516	Up-regulation
AGC_PDK1_PDPK1_ST	Q99683	MAP3K5	O15530	PDPK1	S83	R80Q	80	Missense	distal	-3	no	5.317	4.583	EPSD	TCGA	3.516	Down-regulation
AGC_PDK1_PDPK1_ST	Q99683	MAP3K5	O15530	PDPK1	T838	F839C	839	Missense	proximal	1	no	5.741	-0.083	EPSD	TCGA	3.516	Loss
AGC_PDK1_PDPK1_ST	Q99683	MAP3K5	O15530	PDPK1	S966	S966F	966	Missense	central	0	yes	6.515	0.000	PhosphoSitePlus	TCGA;COSMIC;CCLE	3.516	Loss
AGC_PDK1_PDPK1_ST	Q99683	MAP3K5	O15530	PDPK1	S966	P968L	968	Missense	proximal	2	no	6.515	6.476	PhosphoSitePlus	TCGA;COSMIC	3.516	Down-regulation
AGC_PDK1_PDPK1_ST	Q99683	MAP3K5	O15530	PDPK1	S1033	E1036K	1036	Missense	distal	3	no	4.389	4.244	EPSD	TCGA;COSMIC	3.516	Down-regulation
AGC_PDK1_PDPK1_ST	Q99683	MAP3K5	O15530	PDPK1	S1033	E1036V	1036	Missense	distal	3	no	4.389	4.217	EPSD	TCGA;COSMIC	3.516	Down-regulation
AGC_PDK1_PDPK1_ST	Q99683	MAP3K5	O15530	PDPK1	S1033	D1038Y	1038	Missense	distal	5	no	4.389	4.217	EPSD	TCGA;COSMIC	3.516	Down-regulation
AGC_PDK1_PDPK1_ST	Q99683	MAP3K5	O15530	PDPK1	S1224	S1224N	1224	Missense	central	0	yes	4.607	0.000	EPSD	TCGA	3.516	Loss
AGC_PDK1_PDPK1_ST	Q99683	MAP3K5	O15530	PDPK1	S1224	V1223M	1223	Missense	proximal	-1	no	4.607	4.782	EPSD	TCGA;COSMIC;GDSC;CCLE	3.516	Up-regulation
AGC_PDK1_PDPK1_ST	Q99683	MAP3K5	O15530	PDPK1	S1227	D1233N	1233	Missense	distal	6	no	3.814	3.813	EPSD	TCGA;COSMIC	3.516	Down-regulation
AGC_PDK1_PDPK1_ST	Q99683	MAP3K5	O15530	PDPK1	S1227	S1224N	1224	Missense	distal	-3	no	3.814	3.232	EPSD	TCGA	3.516	Loss
AGC_PDK1_PDPK1_ST	Q99683	MAP3K5	O15530	PDPK1	S1227	V1223M	1223	Missense	distal	-4	no	3.814	3.745	EPSD	TCGA;COSMIC;GDSC;CCLE	3.516	Down-regulation
AGC_PDK1_PDPK1_ST	Q99683	MAP3K5	O15530	PDPK1	T1229	D1233N	1233	Missense	distal	4	no	3.549	3.992	EPSD	TCGA;COSMIC	3.516	Up-regulation
AGC_PDK1_PDPK1_ST	Q99683	MAP3K5	O15530	PDPK1	T1229	S1224N	1224	Missense	distal	-5	no	3.549	3.583	EPSD	TCGA	3.516	Up-regulation
AGC_PDK1_PDPK1_ST	Q99683	MAP3K5	O15530	PDPK1	T1229	V1223M	1223	Missense	distal	-6	no	3.549	3.483	EPSD	TCGA;COSMIC;GDSC;CCLE	3.516	Loss
AGC_PDK1_PDPK1_ST	Q99683	MAP3K5	O15530	PDPK1	S1231	D1233N	1233	Missense	proximal	2	no	3.865	3.916	EPSD	TCGA;COSMIC	3.516	Up-regulation
AGC_PDK1_PDPK1_ST	Q99683	MAP3K5	O15530	PDPK1	S1231	S1224N	1224	Missense	distal	-7	no	3.865	3.658	EPSD	TCGA	3.516	Down-regulation
AGC_PDK1_PDPK1_ST	Q16513	PKN2	O15530	PDPK1	T124	C118Y	118	Missense	distal	-6	no	3.979	3.970	EPSD	TCGA;ICGC	3.516	Down-regulation
AGC_PDK1_PDPK1_ST	Q16513	PKN2	O15530	PDPK1	S306	T304I	304	Missense	proximal	-2	no	6.054	5.812	EPSD	TCGA;ICGC;COSMIC	3.516	Down-regulation
AGC_PDK1_PDPK1_ST	Q16513	PKN2	O15530	PDPK1	S310	T304I	304	Missense	distal	-6	no	3.792	3.922	EPSD	TCGA;ICGC;COSMIC	3.516	Up-regulation
AGC_PDK1_PDPK1_ST	Q16513	PKN2	O15530	PDPK1	S310	N316H	316	Missense	distal	6	no	3.792	3.793	EPSD	TCGA;ICGC	3.516	Up-regulation
AGC_PDK1_PDPK1_ST	Q16513	PKN2	O15530	PDPK1	S310	T314M	314	Missense	distal	4	no	3.792	3.228	EPSD	TCGA;ICGC;COSMIC	3.516	Loss
AGC_PDK1_PDPK1_ST	Q16513	PKN2	O15530	PDPK1	S353	V354F	354	Missense	proximal	1	no	2.546	4.912	EPSD	TCGA;ICGC;COSMIC	3.516	Gain
AGC_PDK1_PDPK1_ST	Q16513	PKN2	O15530	PDPK1	S360	S353L	353	Missense	distal	-7	no	5.874	4.948	EPSD	TCGA;ICGC;COSMIC	3.516	Down-regulation
AGC_PDK1_PDPK1_ST	Q16513	PKN2	O15530	PDPK1	S360	V354F	354	Missense	distal	-6	no	5.874	5.976	EPSD	TCGA;ICGC;COSMIC	3.516	Up-regulation
AGC_PDK1_PDPK1_ST	Q16513	PKN2	O15530	PDPK1	T533	Q537E	537	Missense	distal	4	no	5.008	4.600	EPSD	TCGA;COSMIC	3.516	Down-regulation
AGC_PDK1_PDPK1_ST	Q16513	PKN2	O15530	PDPK1	T533	F534Y	534	Missense	proximal	1	no	5.008	3.629	EPSD	TCGA;COSMIC	3.516	Down-regulation
AGC_PDK1_PDPK1_ST	Q16513	PKN2	O15530	PDPK1	S535	Q537E	537	Missense	proximal	2	no	3.966	3.970	EPSD	TCGA;COSMIC	3.516	Up-regulation
AGC_PDK1_PDPK1_ST	Q16513	PKN2	O15530	PDPK1	S535	F534Y	534	Missense	proximal	-1	no	3.966	4.308	EPSD	TCGA;COSMIC	3.516	Up-regulation
AGC_PDK1_PDPK1_ST	Q16513	PKN2	O15530	PDPK1	S815	E822G	822	Missense	distal	7	no	4.251	4.171	EPSD	TCGA	3.516	Down-regulation
AGC_PDK1_PDPK1_ST	Q16513	PKN2	O15530	PDPK1	S815	M808V	808	Missense	distal	-7	no	4.251	3.833	EPSD	TCGA;COSMIC	3.516	Down-regulation
AGC_PDK1_PDPK1_ST	Q16513	PKN2	O15530	PDPK1	S815	Y810C	810	Missense	distal	-5	no	4.251	4.238	EPSD	TCGA	3.516	Down-regulation
AGC_PDK1_PDPK1_ST	Q16513	PKN2	O15530	PDPK1	T816	E822G	822	Missense	distal	6	no	9.644	9.643	PhosphoSitePlus	TCGA	3.516	Down-regulation
AGC_PDK1_PDPK1_ST	Q16513	PKN2	O15530	PDPK1	T816	Y810C	810	Missense	distal	-6	no	9.644	9.653	PhosphoSitePlus	TCGA	3.516	Up-regulation
AGC_PDK1_PDPK1_ST	Q16513	PKN2	O15530	PDPK1	T958	R961Q	961	Missense	distal	3	no	6.082	6.199	EPSD	TCGA;COSMIC	3.516	Up-regulation
AGC_PDK1_PDPK1_ST	Q02156	PRKCE	O15530	PDPK1	T175	Y176C	176	Missense	proximal	1	no	4.405	-0.040	EPSD	TCGA;ICGC;COSMIC	3.516	Loss
AGC_PDK1_PDPK1_ST	Q02156	PRKCE	O15530	PDPK1	T175	N168I	168	Missense	distal	-7	no	4.405	3.259	EPSD	TCGA;ICGC;COSMIC	3.516	Loss
AGC_PDK1_PDPK1_ST	Q02156	PRKCE	O15530	PDPK1	T309	D305Y	305	Missense	distal	-4	no	4.524	4.564	EPSD	TCGA;ICGC;COSMIC	3.516	Up-regulation
AGC_PDK1_PDPK1_ST	Q02156	PRKCE	O15530	PDPK1	T309	D305N	305	Missense	distal	-4	no	4.524	4.482	EPSD	TCGA;ICGC;COSMIC	3.516	Down-regulation
AGC_PDK1_PDPK1_ST	Q02156	PRKCE	O15530	PDPK1	T309	P310L	310	Missense	proximal	1	no	4.524	2.105	EPSD	TCGA;ICGC;COSMIC	3.516	Loss
AGC_PDK1_PDPK1_ST	Q02156	PRKCE	O15530	PDPK1	T309	V308I	308	Missense	proximal	-1	no	4.524	4.193	EPSD	TCGA;ICGC;COSMIC	3.516	Down-regulation
AGC_PDK1_PDPK1_ST	Q02156	PRKCE	O15530	PDPK1	T309	L306M	306	Missense	distal	-3	no	4.524	5.121	EPSD	TCGA;ICGC;COSMIC	3.516	Up-regulation
AGC_PDK1_PDPK1_ST	Q02156	PRKCE	O15530	PDPK1	S337	E341K	341	Missense	distal	4	no	6.709	7.035	EPSD	TCGA;ICGC;COSMIC	3.516	Up-regulation
AGC_PDK1_PDPK1_ST	Q02156	PRKCE	O15530	PDPK1	S368	R364W	364	Missense	distal	-4	no	4.738	4.817	EPSD	TCGA;ICGC	3.516	Up-regulation
AGC_PDK1_PDPK1_ST	Q02156	PRKCE	O15530	PDPK1	S380	S381F	381	Missense	proximal	1	no	1.947	5.283	EPSD	TCGA;ICGC	3.516	Gain
AGC_PDK1_PDPK1_ST	Q02156	PRKCE	O15530	PDPK1	S388	S381F	381	Missense	distal	-7	no	4.817	3.295	EPSD	TCGA;ICGC	3.516	Loss
AGC_PDK1_PDPK1_ST	Q02156	PRKCE	O15530	PDPK1	S388	S388R	388	Missense	central	0	yes	4.817	0.000	EPSD	TCGA;ICGC;COSMIC	3.516	Loss
AGC_PDK1_PDPK1_ST	Q02156	PRKCE	O15530	PDPK1	S418	G415S	415	Missense	distal	-3	no	4.839	5.708	EPSD	TCGA;ICGC;COSMIC	3.516	Up-regulation
AGC_PDK1_PDPK1_ST	Q02156	PRKCE	O15530	PDPK1	T566	Y573C	573	Missense	distal	7	no	10.563	10.245	PhosphoSitePlus	TCGA	3.516	Down-regulation
AGC_PDK1_PDPK1_ST	P00558	PGK1	O15530	PDPK1	S320	G317S	317	Missense	distal	-3	no	3.082	3.951	EPSD	TCGA	3.516	Gain
AGC_PDK1_PDPK1_ST	P00558	PGK1	O15530	PDPK1	T363	S364Y	364	Missense	proximal	1	no	2.520	4.478	EPSD	TCGA;COSMIC	3.516	Gain
STE_STE11_ASK_MAP3K5_ST	Q9UER7	DAXX	Q99683	MAP3K5	S51	G55S	55	Missense	distal	4	no	19.462	23.760	EPSD	TCGA;ICGC;COSMIC	22.468	Gain
STE_STE11_ASK_MAP3K5_ST	Q9UER7	DAXX	Q99683	MAP3K5	S53	K57E	57	Missense	distal	4	no	27.342	26.593	EPSD	TCGA	22.468	Down-regulation
STE_STE11_ASK_MAP3K5_ST	Q9UER7	DAXX	Q99683	MAP3K5	S53	A47V	47	Missense	distal	-6	no	27.342	27.671	EPSD	TCGA;ICGC;COSMIC	22.468	Up-regulation
STE_STE11_ASK_MAP3K5_ST	Q9UER7	DAXX	Q99683	MAP3K5	S53	G55S	55	Missense	proximal	2	no	27.342	34.703	EPSD	TCGA;ICGC;COSMIC	22.468	Up-regulation
STE_STE11_ASK_MAP3K5_ST	Q9UER7	DAXX	Q99683	MAP3K5	S53	K56N	56	Missense	distal	3	no	27.342	23.906	EPSD	TCGA;ICGC;COSMIC	22.468	Down-regulation
STE_STE11_ASK_MAP3K5_ST	Q9UER7	DAXX	Q99683	MAP3K5	S165	P161R	161	Missense	distal	-4	no	24.658	23.588	EPSD	TCGA;ICGC;COSMIC	22.468	Down-regulation
STE_STE11_ASK_MAP3K5_ST	Q9UER7	DAXX	Q99683	MAP3K5	S165	E172K	172	Missense	distal	7	no	24.658	24.947	EPSD	TCGA;ICGC;COSMIC;CCLE	22.468	Up-regulation
STE_STE11_ASK_MAP3K5_ST	Q9UER7	DAXX	Q99683	MAP3K5	S165	P168S	168	Missense	distal	3	no	24.658	21.811	EPSD	TCGA;ICGC;COSMIC	22.468	Loss
STE_STE11_ASK_MAP3K5_ST	Q9UER7	DAXX	Q99683	MAP3K5	S176	E172K	172	Missense	distal	-4	no	39.634	40.942	PhosphoSitePlus;EPSD	TCGA;ICGC;COSMIC;CCLE	22.468	Up-regulation
STE_STE11_ASK_MAP3K5_ST	Q9UER7	DAXX	Q99683	MAP3K5	S176	S176C	176	Missense	central	0	yes	39.634	0.000	PhosphoSitePlus;EPSD	TCGA;ICGC;COSMIC	22.468	Loss
STE_STE11_ASK_MAP3K5_ST	Q9UER7	DAXX	Q99683	MAP3K5	S176	R180M	180	Missense	distal	4	no	39.634	40.764	PhosphoSitePlus;EPSD	TCGA;ICGC	22.468	Up-regulation
STE_STE11_ASK_MAP3K5_ST	Q9UER7	DAXX	Q99683	MAP3K5	S176	A175T	175	Missense	proximal	-1	no	39.634	40.345	PhosphoSitePlus;EPSD	TCGA;ICGC	22.468	Up-regulation
STE_STE11_ASK_MAP3K5_ST	Q9UER7	DAXX	Q99683	MAP3K5	S184	R190C	190	Missense	distal	6	no	37.891	32.934	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	22.468	Down-regulation
STE_STE11_ASK_MAP3K5_ST	Q9UER7	DAXX	Q99683	MAP3K5	S184	R180M	180	Missense	distal	-4	no	37.891	38.706	EPSD;PhosphoSitePlus	TCGA;ICGC	22.468	Up-regulation
STE_STE11_ASK_MAP3K5_ST	Q9UER7	DAXX	Q99683	MAP3K5	T401	H404Y	404	Missense	distal	3	no	21.642	24.231	EPSD	TCGA;ICGC;COSMIC	22.468	Gain
STE_STE11_ASK_MAP3K5_ST	Q9UER7	DAXX	Q99683	MAP3K5	T401	S402F	402	Missense	proximal	1	no	21.642	24.840	EPSD	TCGA;ICGC;COSMIC	22.468	Gain
STE_STE11_ASK_MAP3K5_ST	Q9UER7	DAXX	Q99683	MAP3K5	S581	S587P	587	Missense	distal	6	no	20.600	22.706	EPSD	TCGA;ICGC;COSMIC	22.468	Gain
STE_STE11_ASK_MAP3K5_ST	Q9UER7	DAXX	Q99683	MAP3K5	S647	G642V	642	Missense	distal	-5	no	23.166	23.510	EPSD	TCGA;ICGC;COSMIC	22.468	Up-regulation
STE_STE11_ASK_MAP3K5_ST	Q9UER7	DAXX	Q99683	MAP3K5	S647	N646S	646	Missense	proximal	-1	no	23.166	23.952	EPSD	TCGA;ICGC	22.468	Up-regulation
STE_STE11_ASK_MAP3K5_ST	Q9UER7	DAXX	Q99683	MAP3K5	T684	S682C	682	Missense	proximal	-2	no	24.662	23.569	EPSD	TCGA;ICGC;COSMIC	22.468	Down-regulation
STE_STE11_ASK_MAP3K5_ST	Q9UER7	DAXX	Q99683	MAP3K5	T684	R685M	685	Missense	proximal	1	no	24.662	22.123	EPSD	TCGA;ICGC	22.468	Loss
STE_STE11_ASK_MAP3K5_ST	P46734	MAP2K3	Q99683	MAP3K5	T39	P38T	38	Missense	proximal	-1	no	25.039	25.729	EPSD	TCGA;COSMIC	22.468	Up-regulation
STE_STE11_ASK_MAP3K5_ST	P46734	MAP2K3	Q99683	MAP3K5	T39	P34R	34	Missense	distal	-5	no	25.039	25.542	EPSD	TCGA;COSMIC	22.468	Up-regulation
STE_STE11_ASK_MAP3K5_ST	P46734	MAP2K3	Q99683	MAP3K5	T39	N37K	37	Missense	proximal	-2	no	25.039	23.924	EPSD	TCGA;COSMIC	22.468	Down-regulation
STE_STE11_ASK_MAP3K5_ST	P46734	MAP2K3	Q99683	MAP3K5	T39	S46P	46	Missense	distal	7	no	25.039	25.440	EPSD	TCGA;COSMIC	22.468	Up-regulation
STE_STE11_ASK_MAP3K5_ST	P46734	MAP2K3	Q99683	MAP3K5	T39	P38L	38	Missense	proximal	-1	no	25.039	25.691	EPSD	TCGA	22.468	Up-regulation
STE_STE11_ASK_MAP3K5_ST	P46734	MAP2K3	Q99683	MAP3K5	T39	R42Q	42	Missense	distal	3	no	25.039	24.175	EPSD	TCGA;GDSC	22.468	Down-regulation
STE_STE11_ASK_MAP3K5_ST	P46734	MAP2K3	Q99683	MAP3K5	T39	R42W	42	Missense	distal	3	no	25.039	25.975	EPSD	TCGA;COSMIC	22.468	Up-regulation
STE_STE11_ASK_MAP3K5_ST	P46734	MAP2K3	Q99683	MAP3K5	T117	D110N	110	Missense	distal	-7	no	29.389	28.470	EPSD	TCGA;COSMIC	22.468	Down-regulation
STE_STE11_ASK_MAP3K5_ST	P46734	MAP2K3	Q99683	MAP3K5	T117	D112N	112	Missense	distal	-5	no	29.389	29.990	EPSD	TCGA;COSMIC	22.468	Up-regulation
STE_STE11_ASK_MAP3K5_ST	P46734	MAP2K3	Q99683	MAP3K5	T117	V118A	118	Missense	proximal	1	no	29.389	26.806	EPSD	TCGA	22.468	Down-regulation
STE_STE11_ASK_MAP3K5_ST	P46734	MAP2K3	Q99683	MAP3K5	S218	M223I	223	Missense	distal	5	no	44.183	43.602	PhosphoSitePlus	TCGA;COSMIC	22.468	Down-regulation
STE_STE11_ASK_MAP3K5_ST	P46734	MAP2K3	Q99683	MAP3K5	S218	A225V	225	Missense	distal	7	no	44.183	44.501	PhosphoSitePlus	TCGA;COSMIC	22.468	Up-regulation
STE_STE11_ASK_MAP3K5_ST	P46734	MAP2K3	Q99683	MAP3K5	S218	S218Y	218	Missense	central	0	yes	44.183	0.000	PhosphoSitePlus	TCGA;CCLE	22.468	Loss
STE_STE11_ASK_MAP3K5_ST	P46734	MAP2K3	Q99683	MAP3K5	S218	S212N	212	Missense	distal	-6	no	44.183	44.064	PhosphoSitePlus	TCGA;COSMIC	22.468	Down-regulation
STE_STE11_ASK_MAP3K5_ST	P46734	MAP2K3	Q99683	MAP3K5	T222	M223I	223	Missense	proximal	1	no	33.198	37.040	EPSD	TCGA;COSMIC	22.468	Up-regulation
STE_STE11_ASK_MAP3K5_ST	P46734	MAP2K3	Q99683	MAP3K5	T222	C227F	227	Missense	distal	5	no	33.198	33.281	EPSD	TCGA;COSMIC	22.468	Up-regulation
STE_STE11_ASK_MAP3K5_ST	P46734	MAP2K3	Q99683	MAP3K5	T222	P229S	229	Missense	distal	7	no	33.198	32.798	EPSD	TCGA;COSMIC	22.468	Down-regulation
STE_STE11_ASK_MAP3K5_ST	P46734	MAP2K3	Q99683	MAP3K5	T222	A225V	225	Missense	distal	3	no	33.198	36.174	EPSD	TCGA;COSMIC	22.468	Up-regulation
STE_STE11_ASK_MAP3K5_ST	P46734	MAP2K3	Q99683	MAP3K5	T222	S218Y	218	Missense	distal	-4	no	33.198	31.989	EPSD	TCGA;CCLE	22.468	Down-regulation
STE_STE11_ASK_MAP3K5_ST	P45983	MAPK8	Q99683	MAP3K5	S179	T178M	178	Missense	proximal	-1	no	29.048	29.006	EPSD	TCGA;ICGC;COSMIC	22.468	Down-regulation
STE_STE11_ASK_MAP3K5_ST	P45983	MAPK8	Q99683	MAP3K5	S179	P184L	184	Missense	distal	5	no	29.048	28.918	EPSD	TCGA;ICGC;COSMIC	22.468	Down-regulation
STE_STE11_ASK_MAP3K5_ST	P45983	MAPK8	Q99683	MAP3K5	T183	T178M	178	Missense	distal	-5	no	46.269	46.084	PhosphoSitePlus;EPSD	TCGA;ICGC;COSMIC	22.468	Down-regulation
STE_STE11_ASK_MAP3K5_ST	P45983	MAPK8	Q99683	MAP3K5	T183	P184L	184	Missense	proximal	1	no	46.269	48.234	PhosphoSitePlus;EPSD	TCGA;ICGC;COSMIC	22.468	Up-regulation
STE_STE11_ASK_MAP3K5_ST	P45983	MAPK8	Q99683	MAP3K5	T183	R189C	189	Missense	distal	6	no	46.269	41.312	PhosphoSitePlus;EPSD	TCGA;ICGC;COSMIC	22.468	Down-regulation
STE_STE11_ASK_MAP3K5_ST	P45983	MAPK8	Q99683	MAP3K5	T183	R189L	189	Missense	distal	6	no	46.269	43.228	PhosphoSitePlus;EPSD	TCGA;ICGC;COSMIC	22.468	Down-regulation
STE_STE11_ASK_MAP3K5_ST	P45983	MAPK8	Q99683	MAP3K5	T183	R189H	189	Missense	distal	6	no	46.269	42.623	PhosphoSitePlus;EPSD	TCGA;ICGC;COSMIC	22.468	Down-regulation
STE_STE11_ASK_MAP3K5_ST	P52564	MAP2K6	Q99683	MAP3K5	S207	K210R	210	Missense	distal	3	no	42.328	42.254	PhosphoSitePlus	TCGA;COSMIC	22.468	Down-regulation
STE_STE11_ASK_MAP3K5_ST	P52564	MAP2K6	Q99683	MAP3K5	S207	S207Y	207	Missense	central	0	yes	42.328	0.000	PhosphoSitePlus	TCGA	22.468	Loss
STE_STE11_ASK_MAP3K5_ST	P52564	MAP2K6	Q99683	MAP3K5	T211	K210R	210	Missense	proximal	-1	no	29.569	29.095	EPSD	TCGA;COSMIC	22.468	Down-regulation
STE_STE11_ASK_MAP3K5_ST	P52564	MAP2K6	Q99683	MAP3K5	T211	S207Y	207	Missense	distal	-4	no	29.569	28.360	EPSD	TCGA	22.468	Down-regulation
STE_STE11_ASK_MAP3K5_ST	Q99683	MAP3K5	Q99683	MAP3K5	S267	Q270L	270	Missense	distal	3	no	35.185	37.151	EPSD	TCGA;ICGC;COSMIC	22.468	Up-regulation
STE_STE11_ASK_MAP3K5_ST	Q99683	MAP3K5	Q99683	MAP3K5	S267	S268Y	268	Missense	proximal	1	no	35.185	40.513	EPSD	TCGA;ICGC	22.468	Up-regulation
STE_STE11_ASK_MAP3K5_ST	Q99683	MAP3K5	Q99683	MAP3K5	S269	Q270L	270	Missense	proximal	1	no	26.107	29.993	EPSD	TCGA;ICGC;COSMIC	22.468	Up-regulation
STE_STE11_ASK_MAP3K5_ST	Q99683	MAP3K5	Q99683	MAP3K5	S269	S268Y	268	Missense	proximal	-1	no	26.107	27.694	EPSD	TCGA;ICGC	22.468	Up-regulation
STE_STE11_ASK_MAP3K5_ST	Q99683	MAP3K5	Q99683	MAP3K5	T813	L810F	810	Missense	distal	-3	no	38.041	39.094	EPSD;PhosphoSitePlus	TCGA;COSMIC	22.468	Up-regulation
STE_STE11_ASK_MAP3K5_ST	Q99683	MAP3K5	Q99683	MAP3K5	T813	K819N	819	Missense	distal	6	no	38.041	40.061	EPSD;PhosphoSitePlus	TCGA;COSMIC	22.468	Up-regulation
STE_STE11_ASK_MAP3K5_ST	Q99683	MAP3K5	Q99683	MAP3K5	T813	I811V	811	Missense	proximal	-2	no	38.041	37.619	EPSD;PhosphoSitePlus	TCGA;COSMIC	22.468	Down-regulation
STE_STE11_ASK_MAP3K5_ST	Q99683	MAP3K5	Q99683	MAP3K5	T813	T813A	813	Missense	central	0	yes	38.041	0.000	EPSD;PhosphoSitePlus	TCGA;COSMIC	22.468	Loss
STE_STE11_ASK_MAP3K5_ST	Q99683	MAP3K5	Q99683	MAP3K5	T813	I811S	811	Missense	proximal	-2	no	38.041	38.274	EPSD;PhosphoSitePlus	TCGA	22.468	Up-regulation
STE_STE11_ASK_MAP3K5_ST	Q99683	MAP3K5	Q99683	MAP3K5	T838	F839C	839	Missense	proximal	1	no	40.805	41.148	PhosphoSitePlus;EPSD	TCGA	22.468	Up-regulation
STE_STE11_ASK_MAP3K5_ST	Q99683	MAP3K5	Q99683	MAP3K5	T842	A847T	847	Missense	distal	5	no	36.339	35.796	EPSD;PhosphoSitePlus	TCGA;COSMIC;GDSC;CCLE	22.468	Down-regulation
STE_STE11_ASK_MAP3K5_ST	Q99683	MAP3K5	Q99683	MAP3K5	T842	F839C	839	Missense	distal	-3	no	36.339	36.261	EPSD;PhosphoSitePlus	TCGA	22.468	Down-regulation
STE_STE11_ASK_MAP3K5_ST	Q99683	MAP3K5	Q99683	MAP3K5	S964	S966F	966	Missense	proximal	2	no	31.722	22.739	EPSD	TCGA;COSMIC;CCLE	22.468	Down-regulation
STE_STE11_ASK_MAP3K5_ST	Q99683	MAP3K5	Q99683	MAP3K5	S964	P968L	968	Missense	distal	4	no	31.722	30.252	EPSD	TCGA;COSMIC	22.468	Down-regulation
STE_STE11_ASK_MAP3K5_ST	Q99683	MAP3K5	Q99683	MAP3K5	S966	S966F	966	Missense	central	0	yes	35.671	0.000	EPSD;PhosphoSitePlus	TCGA;COSMIC;CCLE	22.468	Loss
STE_STE11_ASK_MAP3K5_ST	Q99683	MAP3K5	Q99683	MAP3K5	S966	P968L	968	Missense	proximal	2	no	35.671	32.970	EPSD;PhosphoSitePlus	TCGA;COSMIC	22.468	Down-regulation
STE_STE11_ASK_MAP3K5_ST	Q99683	MAP3K5	Q99683	MAP3K5	S978	E981K	981	Missense	distal	3	no	28.153	29.709	EPSD	TCGA;COSMIC	22.468	Up-regulation
STE_STE11_ASK_MAP3K5_ST	Q99683	MAP3K5	Q99683	MAP3K5	S978	S977T	977	Missense	proximal	-1	no	28.153	29.058	EPSD	TCGA;COSMIC	22.468	Up-regulation
STE_STE11_ASK_MAP3K5_ST	Q99683	MAP3K5	Q99683	MAP3K5	S978	S977I	977	Missense	proximal	-1	no	28.153	29.545	EPSD	TCGA;COSMIC	22.468	Up-regulation
STE_STE11_ASK_MAP3K5_ST	Q99683	MAP3K5	Q99683	MAP3K5	S978	Y982H	982	Missense	distal	4	no	28.153	28.681	EPSD	TCGA;COSMIC	22.468	Up-regulation
STE_STE11_ASK_MAP3K5_ST	Q99683	MAP3K5	Q99683	MAP3K5	T1015	T1015A	1015	Missense	central	0	yes	27.659	0.000	EPSD	TCGA;COSMIC	22.468	Loss
STE_STE11_ASK_MAP3K5_ST	Q99683	MAP3K5	Q99683	MAP3K5	T1015	K1011N	1011	Missense	distal	-4	no	27.659	28.602	EPSD	TCGA	22.468	Up-regulation
STE_STE11_ASK_MAP3K5_ST	Q99683	MAP3K5	Q99683	MAP3K5	T1015	R1014W	1014	Missense	proximal	-1	no	27.659	28.491	EPSD	TCGA;COSMIC	22.468	Up-regulation
STE_STE11_ASK_MAP3K5_ST	Q99683	MAP3K5	Q99683	MAP3K5	S1039	E1036K	1036	Missense	distal	-3	no	23.848	20.192	EPSD	TCGA;COSMIC	22.468	Loss
STE_STE11_ASK_MAP3K5_ST	Q99683	MAP3K5	Q99683	MAP3K5	S1039	E1036V	1036	Missense	distal	-3	no	23.848	23.121	EPSD	TCGA;COSMIC	22.468	Down-regulation
STE_STE11_ASK_MAP3K5_ST	Q99683	MAP3K5	Q99683	MAP3K5	S1039	F1042V	1042	Missense	distal	3	no	23.848	25.652	EPSD	TCGA;COSMIC	22.468	Up-regulation
STE_STE11_ASK_MAP3K5_ST	Q99683	MAP3K5	Q99683	MAP3K5	S1039	D1038Y	1038	Missense	proximal	-1	no	23.848	24.817	EPSD	TCGA;COSMIC	22.468	Up-regulation
STE_STE11_ASK_MAP3K5_ST	Q99683	MAP3K5	Q99683	MAP3K5	T1229	D1233N	1233	Missense	distal	4	no	23.304	24.550	EPSD	TCGA;COSMIC	22.468	Up-regulation
STE_STE11_ASK_MAP3K5_ST	Q99683	MAP3K5	Q99683	MAP3K5	T1229	S1224N	1224	Missense	distal	-5	no	23.304	23.882	EPSD	TCGA	22.468	Up-regulation
STE_STE11_ASK_MAP3K5_ST	Q99683	MAP3K5	Q99683	MAP3K5	T1229	V1223M	1223	Missense	distal	-6	no	23.304	23.116	EPSD	TCGA;COSMIC;GDSC;CCLE	22.468	Down-regulation
STE_STE11_ASK_MAP3K5_ST	Q9Y3F4	STRAP	Q99683	MAP3K5	S312	S312G	312	Missense	central	0	yes	26.412	0.000	EPSD	TCGA;COSMIC	22.468	Loss
STE_STE11_ASK_MAP3K5_ST	Q16539	MAPK14	Q99683	MAP3K5	T180	R186K	186	Missense	distal	6	no	42.356	41.173	PhosphoSitePlus;EPSD	TCGA;ICGC;COSMIC	22.468	Down-regulation
STE_STE11_ASK_MAP3K5_ST	Q16539	MAPK14	Q99683	MAP3K5	T180	R173W	173	Missense	distal	-7	no	42.356	43.621	PhosphoSitePlus;EPSD	TCGA;ICGC;CCLE	22.468	Up-regulation
STE_STE11_ASK_MAP3K5_ST	Q969S3	ZNF622	Q99683	MAP3K5	S141	P144L	144	Missense	distal	3	no	21.965	22.468	EPSD	TCGA;ICGC;COSMIC	22.468	Gain
STE_STE11_ASK_MAP3K5_ST	Q969S3	ZNF622	Q99683	MAP3K5	S141	A138V	138	Missense	distal	-3	no	21.965	23.114	EPSD	TCGA;ICGC	22.468	Gain
STE_STE11_ASK_MAP3K5_ST	Q969S3	ZNF622	Q99683	MAP3K5	S286	D287N	287	Missense	proximal	1	no	24.391	24.627	EPSD	TCGA;ICGC	22.468	Up-regulation
STE_STE11_ASK_MAP3K5_ST	Q969S3	ZNF622	Q99683	MAP3K5	S286	I288T	288	Missense	proximal	2	no	24.391	26.001	EPSD	TCGA;ICGC;COSMIC	22.468	Up-regulation
STE_STE11_ASK_MAP3K5_ST	Q969S3	ZNF622	Q99683	MAP3K5	S286	D287G	287	Missense	proximal	1	no	24.391	28.801	EPSD	TCGA;ICGC;COSMIC	22.468	Up-regulation
STE_STE11_ASK_MAP3K5_ST	Q969S3	ZNF622	Q99683	MAP3K5	S286	D287H	287	Missense	proximal	1	no	24.391	28.043	EPSD	TCGA	22.468	Up-regulation
STE_STE11_ASK_MAP3K5_ST	Q969S3	ZNF622	Q99683	MAP3K5	S314	E319K	319	Missense	distal	5	no	39.848	39.695	EPSD;PhosphoSitePlus	TCGA;ICGC	22.468	Down-regulation
STE_STE11_ASK_MAP3K5_ST	Q969S3	ZNF622	Q99683	MAP3K5	T318	E319K	319	Missense	proximal	1	no	38.038	33.574	PhosphoSitePlus;EPSD	TCGA;ICGC	22.468	Down-regulation
STE_STE11_ASK_MAP3K5_ST	Q15691	MAPRE1	Q99683	MAP3K5	S40	E36K	36	Missense	distal	-4	no	37.183	38.491	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC;CCLE	22.468	Up-regulation
STE_STE11_ASK_MAP3K5_ST	Q15691	MAPRE1	Q99683	MAP3K5	T154	P160S	160	Missense	distal	6	no	35.846	33.740	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	22.468	Down-regulation
STE_STE11_ASK_MAP3K5_ST	Q15691	MAPRE1	Q99683	MAP3K5	T206	K212Q	212	Missense	distal	6	no	41.243	40.945	PhosphoSitePlus;EPSD	TCGA;ICGC;COSMIC	22.468	Down-regulation
STE_STE11_ASK_MAP3K5_ST	O15530	PDPK1	Q99683	MAP3K5	S394	S400Y	400	Missense	distal	6	no	42.051	36.351	EPSD;PhosphoSitePlus	TCGA;COSMIC	22.468	Down-regulation
STE_STE11_ASK_MAP3K5_ST	O15530	PDPK1	Q99683	MAP3K5	S394	Q387P	387	Missense	distal	-7	no	42.051	42.363	EPSD;PhosphoSitePlus	TCGA;COSMIC	22.468	Up-regulation
STE_STE11_ASK_MAP3K5_ST	O15530	PDPK1	Q99683	MAP3K5	S394	S390L	390	Missense	distal	-4	no	42.051	39.756	EPSD;PhosphoSitePlus	TCGA;COSMIC	22.468	Down-regulation
STE_STE11_ASK_MAP3K5_ST	O15530	PDPK1	Q99683	MAP3K5	S396	S400Y	400	Missense	distal	4	no	25.082	22.980	EPSD	TCGA;COSMIC	22.468	Down-regulation
STE_STE11_ASK_MAP3K5_ST	O15530	PDPK1	Q99683	MAP3K5	S396	S390L	390	Missense	distal	-6	no	25.082	25.526	EPSD	TCGA;COSMIC	22.468	Up-regulation
STE_STE11_ASK_MAP3K5_ST	O15530	PDPK1	Q99683	MAP3K5	S398	S400Y	400	Missense	proximal	2	no	40.770	37.462	PhosphoSitePlus;EPSD	TCGA;COSMIC	22.468	Down-regulation
STE_STE11_ASK_MAP3K5_ST	P38936	CDKN1A	Q99683	MAP3K5	S98	R94W	94	Missense	distal	-4	no	39.225	38.146	PhosphoSitePlus	TCGA;ICGC;COSMIC	22.468	Down-regulation
STE_STE11_ASK_MAP3K5_ST	P38936	CDKN1A	Q99683	MAP3K5	S98	R93S	93	Missense	distal	-5	no	39.225	39.261	PhosphoSitePlus	TCGA;ICGC;COSMIC	22.468	Up-regulation
STE_STE11_ASK_MAP3K5_ST	P38936	CDKN1A	Q99683	MAP3K5	S98	R94P	94	Missense	distal	-4	no	39.225	40.295	PhosphoSitePlus	TCGA;ICGC;COSMIC	22.468	Up-regulation
STE_STE11_ASK_MAP3K5_ST	P38936	CDKN1A	Q99683	MAP3K5	S98	P95S	95	Missense	distal	-3	no	39.225	39.755	PhosphoSitePlus	TCGA;ICGC;COSMIC	22.468	Up-regulation
STE_STE11_ASK_MAP3K5_ST	P38936	CDKN1A	Q99683	MAP3K5	S160	S153C	153	Missense	distal	-7	no	24.134	25.905	EPSD	TCGA;ICGC;COSMIC	22.468	Up-regulation
STE_STE11_ASK_MAP3K5_ST	P38936	CDKN1A	Q99683	MAP3K5	S160	R155H	155	Missense	distal	-5	no	24.134	22.814	EPSD	TCGA;ICGC;COSMIC;CCLE	22.468	Down-regulation
STE_STE11_ASK_MAP3K5_ST	P38936	CDKN1A	Q99683	MAP3K5	S160	R162S	162	Missense	proximal	2	no	24.134	31.458	EPSD	TCGA;ICGC;COSMIC	22.468	Up-regulation
STE_STE11_ASK_MAP3K5_ST	P45985	MAP2K4	Q99683	MAP3K5	T56	R58S	58	Missense	proximal	2	no	15.618	22.943	EPSD	TCGA;COSMIC	22.468	Gain
STE_STE11_ASK_MAP3K5_ST	P45985	MAP2K4	Q99683	MAP3K5	S257	S257F	257	Missense	central	0	yes	29.021	0.000	EPSD	TCGA;COSMIC	22.468	Loss
STE_STE11_ASK_MAP3K5_ST	P45985	MAP2K4	Q99683	MAP3K5	S257	S251I	251	Missense	distal	-6	no	29.021	29.449	EPSD	TCGA;COSMIC	22.468	Up-regulation
STE_STE11_ASK_MAP3K5_ST	P45985	MAP2K4	Q99683	MAP3K5	S257	R262K	262	Missense	distal	5	no	29.021	28.078	EPSD	TCGA;COSMIC	22.468	Down-regulation
STE_STE11_ASK_MAP3K5_ST	P45985	MAP2K4	Q99683	MAP3K5	T261	S257F	257	Missense	distal	-4	no	35.797	34.339	PhosphoSitePlus	TCGA;COSMIC	22.468	Down-regulation
STE_STE11_ASK_MAP3K5_ST	P45985	MAP2K4	Q99683	MAP3K5	T261	R262K	262	Missense	proximal	1	no	35.797	34.236	PhosphoSitePlus	TCGA;COSMIC	22.468	Down-regulation
STE_STE11_ASK_MAP3K5_ST	P45985	MAP2K4	Q99683	MAP3K5	T261	G265C	265	Missense	distal	4	no	35.797	37.341	PhosphoSitePlus	TCGA;COSMIC	22.468	Up-regulation
TK_VEGFR_KDR_Y	P35968	KDR	P35968	KDR	Y951	I955F	955	Missense	distal	4	no	75.999	76.106	PhosphoSitePlus;EPSD	TCGA;ICGC;COSMIC	61.410	Up-regulation
TK_VEGFR_KDR_Y	P35968	KDR	P35968	KDR	Y951	G948V	948	Missense	distal	-3	no	75.999	66.131	PhosphoSitePlus;EPSD	TCGA;ICGC;COSMIC	61.410	Down-regulation
TK_VEGFR_KDR_Y	P35968	KDR	P35968	KDR	Y951	P956S	956	Missense	distal	5	no	75.999	75.715	PhosphoSitePlus;EPSD	TCGA;ICGC;COSMIC	61.410	Down-regulation
TK_VEGFR_KDR_Y	P35968	KDR	P35968	KDR	Y951	R944Q	944	Missense	distal	-7	no	75.999	72.608	PhosphoSitePlus;EPSD	TCGA;ICGC;COSMIC;GDSC;CCLE	61.410	Down-regulation
TK_VEGFR_KDR_Y	P35968	KDR	P35968	KDR	Y951	R946H	946	Missense	distal	-5	no	75.999	76.881	PhosphoSitePlus;EPSD	TCGA;ICGC;COSMIC	61.410	Up-regulation
TK_VEGFR_KDR_Y	P35968	KDR	P35968	KDR	Y996	P992A	992	Missense	distal	-4	no	72.861	72.966	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	61.410	Up-regulation
TK_VEGFR_KDR_Y	P35968	KDR	P35968	KDR	Y996	K997E	997	Missense	proximal	1	no	72.861	71.379	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	61.410	Down-regulation
TK_VEGFR_KDR_Y	P35968	KDR	P35968	KDR	Y996	P992S	992	Missense	distal	-4	no	72.861	72.999	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC;GDSC;CCLE	61.410	Up-regulation
TK_VEGFR_KDR_Y	P35968	KDR	P35968	KDR	Y996	D998N	998	Missense	proximal	2	no	72.861	73.412	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	61.410	Up-regulation
TK_VEGFR_KDR_Y	P35968	KDR	P35968	KDR	Y1054	R1051Q	1051	Missense	distal	-3	no	66.935	61.032	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	61.410	Loss
TK_VEGFR_KDR_Y	P35968	KDR	P35968	KDR	Y1054	K1055T	1055	Missense	proximal	1	no	66.935	67.110	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	61.410	Up-regulation
TK_VEGFR_KDR_Y	P35968	KDR	P35968	KDR	Y1054	G1048V	1048	Missense	distal	-6	no	66.935	68.100	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	61.410	Up-regulation
TK_VEGFR_KDR_Y	P35968	KDR	P35968	KDR	Y1054	L1049W	1049	Missense	distal	-5	no	66.935	67.986	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	61.410	Up-regulation
TK_VEGFR_KDR_Y	P35968	KDR	P35968	KDR	Y1054	D1052N	1052	Missense	proximal	-2	no	66.935	61.119	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	61.410	Loss
TK_VEGFR_KDR_Y	P35968	KDR	P35968	KDR	Y1054	D1056N	1056	Missense	proximal	2	no	66.935	67.486	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	61.410	Up-regulation
TK_VEGFR_KDR_Y	P35968	KDR	P35968	KDR	Y1054	D1058Y	1058	Missense	distal	4	no	66.935	67.086	EPSD;PhosphoSitePlus	TCGA;ICGC	61.410	Up-regulation
TK_VEGFR_KDR_Y	P35968	KDR	P35968	KDR	Y1054	I1053M	1053	Missense	proximal	-1	no	66.935	66.923	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	61.410	Down-regulation
TK_VEGFR_KDR_Y	P35968	KDR	P35968	KDR	Y1059	K1055T	1055	Missense	distal	-4	no	66.389	66.223	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	61.410	Down-regulation
TK_VEGFR_KDR_Y	P35968	KDR	P35968	KDR	Y1059	D1052N	1052	Missense	distal	-7	no	66.389	64.309	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	61.410	Down-regulation
TK_VEGFR_KDR_Y	P35968	KDR	P35968	KDR	Y1059	G1063E	1063	Missense	distal	4	no	66.389	66.646	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	61.410	Up-regulation
TK_VEGFR_KDR_Y	P35968	KDR	P35968	KDR	Y1059	D1056N	1056	Missense	distal	-3	no	66.389	61.380	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	61.410	Loss
TK_VEGFR_KDR_Y	P35968	KDR	P35968	KDR	Y1059	R1066C	1066	Missense	distal	7	no	66.389	65.035	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC;GDSC;CCLE	61.410	Down-regulation
TK_VEGFR_KDR_Y	P35968	KDR	P35968	KDR	Y1059	D1058Y	1058	Missense	proximal	-1	no	66.389	66.397	EPSD;PhosphoSitePlus	TCGA;ICGC	61.410	Up-regulation
TK_VEGFR_KDR_Y	P35968	KDR	P35968	KDR	Y1059	I1053M	1053	Missense	distal	-6	no	66.389	65.897	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	61.410	Down-regulation
TK_VEGFR_KDR_Y	P35968	KDR	P35968	KDR	Y1175	A1168T	1168	Missense	distal	-7	no	74.229	72.244	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	61.410	Down-regulation
TK_VEGFR_KDR_Y	P35968	KDR	P35968	KDR	Y1175	D1174Y	1174	Missense	proximal	-1	no	74.229	74.237	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	61.410	Up-regulation
TK_VEGFR_KDR_Y	P35968	KDR	P35968	KDR	Y1214	S1221I	1221	Missense	distal	7	no	92.464	87.410	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	61.410	Down-regulation
TK_VEGFR_KDR_Y	P35968	KDR	P35968	KDR	Y1214	P1210S	1210	Missense	distal	-4	no	92.464	92.601	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	61.410	Up-regulation
TK_VEGFR_KDR_Y	P35968	KDR	P35968	KDR	Y1214	H1213Y	1213	Missense	proximal	-1	no	92.464	92.490	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	61.410	Up-regulation
TK_VEGFR_KDR_Y	P35968	KDR	P35968	KDR	Y1214	A1218P	1218	Missense	distal	4	no	92.464	92.792	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	61.410	Up-regulation
TK_VEGFR_KDR_Y	P35968	KDR	P35968	KDR	Y1305	G1304D	1304	Missense	proximal	-1	no	76.177	76.094	EPSD	TCGA;ICGC;COSMIC	61.410	Down-regulation
TK_VEGFR_KDR_Y	P35968	KDR	P35968	KDR	Y1305	D1312N	1312	Missense	distal	7	no	76.177	78.372	EPSD	TCGA;ICGC;COSMIC;GDSC;CCLE	61.410	Up-regulation
TK_VEGFR_KDR_Y	P35968	KDR	P35968	KDR	Y1305	G1298S	1298	Missense	distal	-7	no	76.177	72.999	EPSD	TCGA;ICGC;COSMIC	61.410	Down-regulation
TK_VEGFR_KDR_Y	P35968	KDR	P35968	KDR	Y1305	G1304S	1304	Missense	proximal	-1	no	76.177	76.193	EPSD	TCGA;ICGC;COSMIC	61.410	Up-regulation
TK_VEGFR_KDR_Y	P35968	KDR	P35968	KDR	Y1309	D1315G	1315	Missense	distal	6	no	71.775	71.469	EPSD	TCGA;ICGC;COSMIC	61.410	Down-regulation
TK_VEGFR_KDR_Y	P35968	KDR	P35968	KDR	Y1309	G1304D	1304	Missense	distal	-5	no	71.775	71.996	EPSD	TCGA;ICGC;COSMIC	61.410	Up-regulation
TK_VEGFR_KDR_Y	P35968	KDR	P35968	KDR	Y1309	D1312N	1312	Missense	distal	3	no	71.775	71.594	EPSD	TCGA;ICGC;COSMIC;GDSC;CCLE	61.410	Down-regulation
TK_VEGFR_KDR_Y	P35968	KDR	P35968	KDR	Y1309	G1304S	1304	Missense	distal	-5	no	71.775	71.169	EPSD	TCGA;ICGC;COSMIC	61.410	Down-regulation
TK_VEGFR_KDR_Y	P35968	KDR	P35968	KDR	Y1319	L1326F	1326	Missense	distal	7	no	75.004	71.697	EPSD	TCGA;ICGC;COSMIC	61.410	Down-regulation
TK_VEGFR_KDR_Y	P35968	KDR	P35968	KDR	Y1319	D1315G	1315	Missense	distal	-4	no	75.004	75.087	EPSD	TCGA;ICGC;COSMIC	61.410	Up-regulation
TK_VEGFR_KDR_Y	P35968	KDR	P35968	KDR	Y1319	D1312N	1312	Missense	distal	-7	no	75.004	72.924	EPSD	TCGA;ICGC;COSMIC;GDSC;CCLE	61.410	Down-regulation
TK_VEGFR_KDR_Y	P35968	KDR	P35968	KDR	Y1319	Y1319C	1319	Missense	central	0	yes	75.004	0.000	EPSD	TCGA;ICGC;COSMIC	61.410	Loss
TK_VEGFR_KDR_Y	P07737	PFN1	P35968	KDR	Y129	R136W	136	Missense	distal	7	no	78.064	71.135	PhosphoSitePlus	TCGA;COSMIC	61.410	Down-regulation
TK_VEGFR_KDR_Y	P07737	PFN1	P35968	KDR	Y129	H134L	134	Missense	distal	5	no	78.064	80.354	PhosphoSitePlus	TCGA;ICGC;COSMIC	61.410	Up-regulation
TK_VEGFR_KDR_Y	P07737	PFN1	P35968	KDR	Y129	K127R	127	Missense	proximal	-2	no	78.064	65.660	PhosphoSitePlus	TCGA	61.410	Down-regulation
AGC_GRK_GRK_GRK5_ST	P07550	ADRB2	P34947	GRK5	S261	S262F	262	Missense	proximal	1	no	2.394	2.385	EPSD	TCGA;ICGC;COSMIC	1.854	Down-regulation
AGC_GRK_GRK_GRK5_ST	P07550	ADRB2	P34947	GRK5	S261	K267T	267	Missense	distal	6	no	2.394	2.413	EPSD	TCGA;ICGC	1.854	Up-regulation
AGC_GRK_GRK_GRK5_ST	P26038	MSN	P34947	GRK5	S214	S207N	207	Missense	distal	-7	no	1.757	1.865	EPSD	TCGA;ICGC;COSMIC	1.854	Gain
AGC_GRK_GRK_GRK5_ST	P26038	MSN	P34947	GRK5	S504	R503C	503	Missense	proximal	-1	no	2.004	2.065	EPSD	TCGA;ICGC;COSMIC	1.854	Up-regulation
AGC_GRK_GRK_GRK5_ST	P26038	MSN	P34947	GRK5	S504	R508C	508	Missense	distal	4	no	2.004	2.011	EPSD	TCGA;ICGC;COSMIC	1.854	Up-regulation
AGC_GRK_GRK_GRK5_ST	P26038	MSN	P34947	GRK5	S504	R503H	503	Missense	proximal	-1	no	2.004	1.947	EPSD	TCGA;ICGC;COSMIC	1.854	Down-regulation
AGC_GRK_GRK_GRK5_ST	P26038	MSN	P34947	GRK5	S504	E505K	505	Missense	proximal	1	no	2.004	1.632	EPSD	TCGA;ICGC;COSMIC	1.854	Loss
AGC_GRK_GRK_GRK5_ST	P26038	MSN	P34947	GRK5	T509	R503C	503	Missense	distal	-6	no	1.943	2.189	EPSD	TCGA;ICGC;COSMIC	1.854	Up-regulation
AGC_GRK_GRK_GRK5_ST	P26038	MSN	P34947	GRK5	T509	R508C	508	Missense	proximal	-1	no	1.943	2.004	EPSD	TCGA;ICGC;COSMIC	1.854	Up-regulation
AGC_GRK_GRK_GRK5_ST	P26038	MSN	P34947	GRK5	T509	R503H	503	Missense	distal	-6	no	1.943	1.973	EPSD	TCGA;ICGC;COSMIC	1.854	Up-regulation
AGC_GRK_GRK_GRK5_ST	P26038	MSN	P34947	GRK5	T509	E505K	505	Missense	distal	-4	no	1.943	1.938	EPSD	TCGA;ICGC;COSMIC	1.854	Down-regulation
AGC_GRK_GRK_GRK5_ST	P26038	MSN	P34947	GRK5	T510	R503C	503	Missense	distal	-7	no	2.188	1.980	EPSD	TCGA;ICGC;COSMIC	1.854	Down-regulation
AGC_GRK_GRK_GRK5_ST	P26038	MSN	P34947	GRK5	T510	R508C	508	Missense	proximal	-2	no	2.188	2.170	EPSD	TCGA;ICGC;COSMIC	1.854	Down-regulation
AGC_GRK_GRK_GRK5_ST	P26038	MSN	P34947	GRK5	T510	R503H	503	Missense	distal	-7	no	2.188	2.154	EPSD	TCGA;ICGC;COSMIC	1.854	Down-regulation
AGC_GRK_GRK_GRK5_ST	P26038	MSN	P34947	GRK5	T510	E505K	505	Missense	distal	-5	no	2.188	2.155	EPSD	TCGA;ICGC;COSMIC	1.854	Down-regulation
AGC_GRK_GRK_GRK5_ST	P34947	GRK5	P34947	GRK5	S484	T485I	485	Missense	proximal	1	no	4.708	4.217	EPSD;PhosphoSitePlus	TCGA;ICGC	1.854	Down-regulation
AGC_GRK_GRK_GRK5_ST	P34947	GRK5	P34947	GRK5	T485	T485I	485	Missense	central	0	yes	4.817	0.000	PhosphoSitePlus;EPSD	TCGA;ICGC	1.854	Loss
AGC_GRK_GRK_GRK5_ST	P04637	TP53	P34947	GRK5	S9	P4L	4	Missense	distal	-5	no	2.827	2.957	EPSD	TCGA;ICGC;COSMIC	1.854	Up-regulation
AGC_GRK_GRK_GRK5_ST	P04637	TP53	P34947	GRK5	S33	P27S	27	Missense	distal	-6	no	3.196	3.172	EPSD	TCGA;ICGC;COSMIC	1.854	Down-regulation
AGC_GRK_GRK_GRK5_ST	P04637	TP53	P34947	GRK5	S33	P27L	27	Missense	distal	-6	no	3.196	3.218	EPSD	TCGA;ICGC;COSMIC;GDSC;CCLE	1.854	Up-regulation
AGC_GRK_GRK_GRK5_ST	P04637	TP53	P34947	GRK5	T55	D57N	57	Missense	proximal	2	no	4.317	4.533	PhosphoSitePlus	TCGA;ICGC;COSMIC	1.854	Up-regulation
AGC_GRK_GRK_GRK5_ST	P04637	TP53	P34947	GRK5	T55	D48N	48	Missense	distal	-7	no	4.317	4.427	PhosphoSitePlus	TCGA;ICGC;COSMIC;GDSC;CCLE	1.854	Up-regulation
AGC_GRK_GRK_GRK5_ST	P04637	TP53	P34947	GRK5	T55	D61G	61	Missense	distal	6	no	4.317	4.316	PhosphoSitePlus	TCGA;ICGC;COSMIC	1.854	Down-regulation
AGC_GRK_GRK_GRK5_ST	P04637	TP53	P34947	GRK5	T150	P151A	151	Missense	proximal	1	no	1.750	1.915	EPSD	TCGA;ICGC;COSMIC;CCLE	1.854	Gain
AGC_GRK_GRK_GRK5_ST	P04637	TP53	P34947	GRK5	T150	T155N	155	Missense	distal	5	no	1.750	2.052	EPSD	TCGA;ICGC;COSMIC;GDSC;CCLE	1.854	Gain
AGC_GRK_GRK_GRK5_ST	P04637	TP53	P34947	GRK5	T150	P151T	151	Missense	proximal	1	no	1.750	2.017	EPSD	TCGA;ICGC;COSMIC	1.854	Gain
AGC_GRK_GRK_GRK5_ST	P04637	TP53	P34947	GRK5	T150	P151R	151	Missense	proximal	1	no	1.750	1.898	EPSD	TCGA;ICGC;COSMIC	1.854	Gain
AGC_GRK_GRK_GRK5_ST	P04637	TP53	P34947	GRK5	T150	P151L	151	Missense	proximal	1	no	1.750	1.897	EPSD	TCGA;ICGC;COSMIC	1.854	Gain
AGC_GRK_GRK_GRK5_ST	P04637	TP53	P34947	GRK5	S313	K319N	319	Missense	distal	6	no	1.908	1.885	EPSD	TCGA;ICGC;COSMIC	1.854	Down-regulation
AGC_GRK_GRK_GRK5_ST	P04637	TP53	P34947	GRK5	S313	A307V	307	Missense	distal	-6	no	1.908	2.014	EPSD	TCGA;ICGC;COSMIC;GDSC	1.854	Up-regulation
AGC_GRK_GRK_GRK5_ST	P04637	TP53	P34947	GRK5	S313	K320E	320	Missense	distal	7	no	1.908	2.015	EPSD	TCGA;ICGC;COSMIC	1.854	Up-regulation
AGC_GRK_GRK_GRK5_ST	P04637	TP53	P34947	GRK5	S313	S315C	315	Missense	proximal	2	no	1.908	1.518	EPSD	TCGA;ICGC;COSMIC	1.854	Loss
AGC_GRK_GRK_GRK5_ST	P37840	SNCA	P34947	GRK5	S129	D135Y	135	Missense	distal	6	no	1.896	1.872	PhosphoSitePlus	TCGA;ICGC;COSMIC	1.854	Down-regulation
AGC_GRK_GRK_GRK5_ST	P37840	SNCA	P34947	GRK5	S129	S129F	129	Missense	central	0	yes	1.896	0.000	PhosphoSitePlus	TCGA;ICGC;COSMIC	1.854	Loss
CMGC_CK2_CSNK2A2_ST	P18887	XRCC1	P19784	CSNK2A2	S421	E424K	424	Missense	distal	3	no	0.001	0.000	EPSD	TCGA;ICGC;COSMIC	0.001	Loss
CMGC_CK2_CSNK2A2_ST	P18887	XRCC1	P19784	CSNK2A2	T523	T523M	523	Missense	central	0	yes	0.001	0.000	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	0.001	Loss
CMGC_CK2_CSNK2A2_ST	P35222	CTNNB1	P19784	CSNK2A2	T3	T3A	3	Missense	central	0	yes	0.001	0.000	EPSD	TCGA;COSMIC	0.001	Loss
CMGC_CK2_CSNK2A2_ST	P35222	CTNNB1	P19784	CSNK2A2	T3	D6A	6	Missense	distal	3	no	0.001	0.000	EPSD	TCGA;ICGC;COSMIC	0.001	Loss
CMGC_CK2_CSNK2A2_ST	P35222	CTNNB1	P19784	CSNK2A2	S29	D32H	32	Missense	distal	3	no	0.001	0.000	EPSD;PhosphoSitePlus	TCGA;COSMIC	0.001	Loss
CMGC_CK2_CSNK2A2_ST	P35222	CTNNB1	P19784	CSNK2A2	S29	D32G	32	Missense	distal	3	no	0.001	0.000	EPSD;PhosphoSitePlus	TCGA;COSMIC	0.001	Loss
CMGC_CK2_CSNK2A2_ST	P35222	CTNNB1	P19784	CSNK2A2	S29	D32V	32	Missense	distal	3	no	0.001	0.000	EPSD;PhosphoSitePlus	TCGA;COSMIC;CCLE	0.001	Loss
CMGC_CK2_CSNK2A2_ST	P35222	CTNNB1	P19784	CSNK2A2	S29	D32Y	32	Missense	distal	3	no	0.001	0.000	EPSD;PhosphoSitePlus	TCGA;COSMIC;CCLE	0.001	Loss
CMGC_CK2_CSNK2A2_ST	P35222	CTNNB1	P19784	CSNK2A2	S29	D32N	32	Missense	distal	3	no	0.001	0.000	EPSD;PhosphoSitePlus	TCGA;COSMIC;CCLE	0.001	Loss
CMGC_CK2_CSNK2A2_ST	P35222	CTNNB1	P19784	CSNK2A2	S29	D32A	32	Missense	distal	3	no	0.001	0.000	EPSD;PhosphoSitePlus	TCGA;COSMIC	0.001	Loss
CMGC_CK2_CSNK2A2_ST	P35222	CTNNB1	P19784	CSNK2A2	T289	K292E	292	Missense	distal	3	no	0.000	0.001	EPSD	TCGA;COSMIC	0.001	Gain
CMGC_CK2_CSNK2A2_ST	P35222	CTNNB1	P19784	CSNK2A2	S646	S646C	646	Missense	central	0	yes	0.001	0.000	EPSD	TCGA;COSMIC	0.001	Loss
CMGC_CK2_CSNK2A2_ST	P35222	CTNNB1	P19784	CSNK2A2	S646	E649Q	649	Missense	distal	3	no	0.001	0.000	EPSD	TCGA;COSMIC	0.001	Loss
CMGC_CK2_CSNK2A2_ST	Q9UQE7	SMC3	P19784	CSNK2A2	T18	D21H	21	Missense	distal	3	no	0.001	0.000	EPSD	TCGA;ICGC;COSMIC	0.001	Loss
CMGC_CK2_CSNK2A2_ST	Q9UQE7	SMC3	P19784	CSNK2A2	S674	E677K	677	Missense	distal	3	no	0.001	0.000	EPSD	TCGA;ICGC;COSMIC	0.001	Loss
CMGC_CK2_CSNK2A2_ST	Q9UQE7	SMC3	P19784	CSNK2A2	S1013	S1013L	1013	Missense	central	0	yes	0.001	0.000	EPSD	TCGA;ICGC;COSMIC	0.001	Loss
CMGC_CK2_CSNK2A2_ST	P04818	TYMS	P19784	CSNK2A2	S66	S66N	66	Missense	central	0	yes	0.001	0.000	EPSD	TCGA;ICGC;COSMIC	0.001	Loss
CMGC_CK2_CSNK2A2_ST	P04818	TYMS	P19784	CSNK2A2	S124	S124F	124	Missense	central	0	yes	0.001	0.000	PhosphoSitePlus	TCGA;ICGC;COSMIC	0.001	Loss
CMGC_CK2_CSNK2A2_ST	Q00613	HSF1	P19784	CSNK2A2	S283	E286K	286	Missense	distal	3	no	0.001	0.000	EPSD	TCGA;COSMIC	0.001	Loss
CMGC_CK2_CSNK2A2_ST	Q00613	HSF1	P19784	CSNK2A2	S438	E441K	441	Missense	distal	3	no	0.001	0.000	EPSD	TCGA;COSMIC	0.001	Loss
TKL_STKR_STKR1_ACVRL1_ST	P17813	ENG	P37023	ACVRL1	S646	S653F	653	Missense	distal	7	no	2.481	2.468	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	0.461	Down-regulation
TKL_STKR_STKR1_ACVRL1_ST	P17813	ENG	P37023	ACVRL1	S649	S653F	653	Missense	distal	4	no	2.001	1.823	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	0.461	Down-regulation
TKL_STKR_STKR1_ACVRL1_ST	P17813	ENG	P37023	ACVRL1	T654	S653F	653	Missense	proximal	-1	no	1.790	1.753	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	0.461	Down-regulation
TKL_LRRK_LRRK2_ST	Q5S007	LRRK2	Q5S007	LRRK2	T358	W359R	359	Missense	proximal	1	no	16.532	17.340	EPSD	TCGA;ICGC;COSMIC	15.080	Up-regulation
TKL_LRRK_LRRK2_ST	Q5S007	LRRK2	Q5S007	LRRK2	T358	T358M	358	Missense	central	0	yes	16.532	0.000	EPSD	TCGA;ICGC;COSMIC	15.080	Loss
TKL_LRRK_LRRK2_ST	Q5S007	LRRK2	Q5S007	LRRK2	T358	K362M	362	Missense	distal	4	no	16.532	16.119	EPSD	TCGA;ICGC;COSMIC	15.080	Down-regulation
TKL_LRRK_LRRK2_ST	Q5S007	LRRK2	Q5S007	LRRK2	T358	H365Q	365	Missense	distal	7	no	16.532	16.429	EPSD	TCGA;ICGC;COSMIC	15.080	Down-regulation
TKL_LRRK_LRRK2_ST	Q5S007	LRRK2	Q5S007	LRRK2	T358	K364N	364	Missense	distal	6	no	16.532	16.221	EPSD	TCGA;ICGC;COSMIC	15.080	Down-regulation
TKL_LRRK_LRRK2_ST	Q5S007	LRRK2	Q5S007	LRRK2	T424	L425P	425	Missense	proximal	1	no	17.358	17.263	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	15.080	Down-regulation
TKL_LRRK_LRRK2_ST	Q5S007	LRRK2	Q5S007	LRRK2	T524	K529R	529	Missense	distal	5	no	17.972	17.932	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	15.080	Down-regulation
TKL_LRRK_LRRK2_ST	Q5S007	LRRK2	Q5S007	LRRK2	T524	E522K	522	Missense	proximal	-2	no	17.972	18.201	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	15.080	Up-regulation
TKL_LRRK_LRRK2_ST	Q5S007	LRRK2	Q5S007	LRRK2	T524	E525A	525	Missense	proximal	1	no	17.972	17.920	EPSD;PhosphoSitePlus	TCGA;ICGC	15.080	Down-regulation
TKL_LRRK_LRRK2_ST	Q5S007	LRRK2	Q5S007	LRRK2	T776	D770N	770	Missense	distal	-6	no	16.256	15.520	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	15.080	Down-regulation
TKL_LRRK_LRRK2_ST	Q5S007	LRRK2	Q5S007	LRRK2	T776	D770H	770	Missense	distal	-6	no	16.256	14.563	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	15.080	Loss
TKL_LRRK_LRRK2_ST	Q5S007	LRRK2	Q5S007	LRRK2	T776	R772Q	772	Missense	distal	-4	no	16.256	15.677	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	15.080	Down-regulation
TKL_LRRK_LRRK2_ST	Q5S007	LRRK2	Q5S007	LRRK2	T776	A774V	774	Missense	proximal	-2	no	16.256	15.928	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	15.080	Down-regulation
TKL_LRRK_LRRK2_ST	Q5S007	LRRK2	Q5S007	LRRK2	T826	T833I	833	Missense	distal	7	no	15.693	15.686	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	15.080	Down-regulation
TKL_LRRK_LRRK2_ST	Q5S007	LRRK2	Q5S007	LRRK2	T826	Q832R	832	Missense	distal	6	no	15.693	15.179	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	15.080	Down-regulation
TKL_LRRK_LRRK2_ST	Q5S007	LRRK2	Q5S007	LRRK2	T833	L839I	839	Missense	distal	6	no	16.763	16.623	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	15.080	Down-regulation
TKL_LRRK_LRRK2_ST	Q5S007	LRRK2	Q5S007	LRRK2	T833	L839P	839	Missense	distal	6	no	16.763	16.001	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	15.080	Down-regulation
TKL_LRRK_LRRK2_ST	Q5S007	LRRK2	Q5S007	LRRK2	T833	I835T	835	Missense	proximal	2	no	16.763	17.287	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	15.080	Up-regulation
TKL_LRRK_LRRK2_ST	Q5S007	LRRK2	Q5S007	LRRK2	T833	T833I	833	Missense	central	0	yes	16.763	0.000	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	15.080	Loss
TKL_LRRK_LRRK2_ST	Q5S007	LRRK2	Q5S007	LRRK2	T833	Q832R	832	Missense	proximal	-1	no	16.763	17.151	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	15.080	Up-regulation
TKL_LRRK_LRRK2_ST	Q5S007	LRRK2	Q5S007	LRRK2	T833	A836S	836	Missense	distal	3	no	16.763	16.679	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	15.080	Down-regulation
TKL_LRRK_LRRK2_ST	Q5S007	LRRK2	Q5S007	LRRK2	T838	L839I	839	Missense	proximal	1	no	17.022	16.973	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	15.080	Down-regulation
TKL_LRRK_LRRK2_ST	Q5S007	LRRK2	Q5S007	LRRK2	T838	L839P	839	Missense	proximal	1	no	17.022	16.926	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	15.080	Down-regulation
TKL_LRRK_LRRK2_ST	Q5S007	LRRK2	Q5S007	LRRK2	T838	I835T	835	Missense	distal	-3	no	17.022	16.875	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	15.080	Down-regulation
TKL_LRRK_LRRK2_ST	Q5S007	LRRK2	Q5S007	LRRK2	T838	T833I	833	Missense	distal	-5	no	17.022	17.100	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	15.080	Up-regulation
TKL_LRRK_LRRK2_ST	Q5S007	LRRK2	Q5S007	LRRK2	T838	R841T	841	Missense	distal	3	no	17.022	16.712	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	15.080	Down-regulation
TKL_LRRK_LRRK2_ST	Q5S007	LRRK2	Q5S007	LRRK2	T838	Q832R	832	Missense	distal	-6	no	17.022	17.052	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	15.080	Up-regulation
TKL_LRRK_LRRK2_ST	Q5S007	LRRK2	Q5S007	LRRK2	T838	V843M	843	Missense	distal	5	no	17.022	16.427	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	15.080	Down-regulation
TKL_LRRK_LRRK2_ST	Q5S007	LRRK2	Q5S007	LRRK2	T838	A836S	836	Missense	proximal	-2	no	17.022	17.184	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	15.080	Up-regulation
TKL_LRRK_LRRK2_ST	Q5S007	LRRK2	Q5S007	LRRK2	S1124	S1124F	1124	Missense	central	0	yes	16.883	0.000	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	15.080	Loss
TKL_LRRK_LRRK2_ST	Q5S007	LRRK2	Q5S007	LRRK2	S1159	R1161T	1161	Missense	proximal	2	no	15.902	15.916	EPSD	TCGA;ICGC;COSMIC	15.080	Up-regulation
TKL_LRRK_LRRK2_ST	Q5S007	LRRK2	Q5S007	LRRK2	S1159	E1156Q	1156	Missense	distal	-3	no	15.902	15.313	EPSD	TCGA	15.080	Down-regulation
TKL_LRRK_LRRK2_ST	Q5S007	LRRK2	Q5S007	LRRK2	S1159	R1161G	1161	Missense	proximal	2	no	15.902	15.594	EPSD	TCGA;ICGC;COSMIC	15.080	Down-regulation
TKL_LRRK_LRRK2_ST	Q5S007	LRRK2	Q5S007	LRRK2	S1159	R1161K	1161	Missense	proximal	2	no	15.902	15.850	EPSD	TCGA;ICGC;COSMIC;CCLE	15.080	Down-regulation
TKL_LRRK_LRRK2_ST	Q5S007	LRRK2	Q5S007	LRRK2	S1159	M1162I	1162	Missense	distal	3	no	15.902	15.706	EPSD	TCGA;ICGC;COSMIC	15.080	Down-regulation
TKL_LRRK_LRRK2_ST	Q5S007	LRRK2	Q5S007	LRRK2	S1159	V1155M	1155	Missense	distal	-4	no	15.902	16.664	EPSD	TCGA;ICGC;COSMIC	15.080	Up-regulation
TKL_LRRK_LRRK2_ST	Q5S007	LRRK2	Q5S007	LRRK2	S1159	E1156D	1156	Missense	distal	-3	no	15.902	15.990	EPSD	TCGA;ICGC	15.080	Up-regulation
TKL_LRRK_LRRK2_ST	Q5S007	LRRK2	Q5S007	LRRK2	S1159	F1164V	1164	Missense	distal	5	no	15.902	15.929	EPSD	TCGA;ICGC	15.080	Up-regulation
TKL_LRRK_LRRK2_ST	Q5S007	LRRK2	Q5S007	LRRK2	S1219	A1215T	1215	Missense	distal	-4	no	15.640	16.011	EPSD	TCGA;ICGC;COSMIC	15.080	Up-regulation
TKL_LRRK_LRRK2_ST	Q5S007	LRRK2	Q5S007	LRRK2	S1219	R1223W	1223	Missense	distal	4	no	15.640	11.945	EPSD	TCGA;ICGC;COSMIC	15.080	Loss
TKL_LRRK_LRRK2_ST	Q5S007	LRRK2	Q5S007	LRRK2	S1219	H1216L	1216	Missense	distal	-3	no	15.640	15.523	EPSD	TCGA;ICGC;COSMIC	15.080	Down-regulation
TKL_LRRK_LRRK2_ST	Q5S007	LRRK2	Q5S007	LRRK2	S1253	R1246T	1246	Missense	distal	-7	no	15.314	14.936	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	15.080	Loss
TKL_LRRK_LRRK2_ST	Q5S007	LRRK2	Q5S007	LRRK2	S1253	K1256N	1256	Missense	distal	3	no	15.314	15.195	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	15.080	Down-regulation
TKL_LRRK_LRRK2_ST	Q5S007	LRRK2	Q5S007	LRRK2	S1283	N1286I	1286	Missense	distal	3	no	15.818	15.842	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	15.080	Up-regulation
TKL_LRRK_LRRK2_ST	Q5S007	LRRK2	Q5S007	LRRK2	S1283	S1283F	1283	Missense	central	0	yes	15.818	0.000	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC;GDSC;CCLE	15.080	Loss
TKL_LRRK_LRRK2_ST	Q5S007	LRRK2	Q5S007	LRRK2	S1283	F1284V	1284	Missense	proximal	1	no	15.818	15.766	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	15.080	Down-regulation
TKL_LRRK_LRRK2_ST	Q5S007	LRRK2	Q5S007	LRRK2	S1283	K1290T	1290	Missense	distal	7	no	15.818	15.872	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	15.080	Up-regulation
TKL_LRRK_LRRK2_ST	Q5S007	LRRK2	Q5S007	LRRK2	S1292	P1298S	1298	Missense	distal	6	no	17.748	17.990	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	15.080	Up-regulation
TKL_LRRK_LRRK2_ST	Q5S007	LRRK2	Q5S007	LRRK2	S1292	N1286I	1286	Missense	distal	-6	no	17.748	18.563	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	15.080	Up-regulation
TKL_LRRK_LRRK2_ST	Q5S007	LRRK2	Q5S007	LRRK2	S1292	I1294M	1294	Missense	proximal	2	no	17.748	17.929	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	15.080	Up-regulation
TKL_LRRK_LRRK2_ST	Q5S007	LRRK2	Q5S007	LRRK2	S1292	K1290T	1290	Missense	proximal	-2	no	17.748	17.414	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	15.080	Down-regulation
TKL_LRRK_LRRK2_ST	Q5S007	LRRK2	Q5S007	LRRK2	T1368	I1371K	1371	Missense	distal	3	no	17.975	18.069	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	15.080	Up-regulation
TKL_LRRK_LRRK2_ST	Q5S007	LRRK2	Q5S007	LRRK2	T1368	A1367V	1367	Missense	proximal	-1	no	17.975	16.858	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	15.080	Down-regulation
TKL_LRRK_LRRK2_ST	Q5S007	LRRK2	Q5S007	LRRK2	S1403	H1407N	1407	Missense	distal	4	no	16.773	17.093	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	15.080	Up-regulation
TKL_LRRK_LRRK2_ST	Q5S007	LRRK2	Q5S007	LRRK2	S1403	E1399D	1399	Missense	distal	-4	no	16.773	16.113	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	15.080	Down-regulation
TKL_LRRK_LRRK2_ST	Q5S007	LRRK2	Q5S007	LRRK2	T1404	H1407N	1407	Missense	distal	3	no	16.083	16.057	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	15.080	Down-regulation
TKL_LRRK_LRRK2_ST	Q5S007	LRRK2	Q5S007	LRRK2	T1404	E1399D	1399	Missense	distal	-5	no	16.083	15.943	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	15.080	Down-regulation
TKL_LRRK_LRRK2_ST	Q5S007	LRRK2	Q5S007	LRRK2	T1410	H1407N	1407	Missense	distal	-3	no	17.094	17.226	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	15.080	Up-regulation
TKL_LRRK_LRRK2_ST	Q5S007	LRRK2	Q5S007	LRRK2	S1443	A1442T	1442	Missense	proximal	-1	no	16.548	15.932	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	15.080	Down-regulation
TKL_LRRK_LRRK2_ST	Q5S007	LRRK2	Q5S007	LRRK2	S1443	R1441C	1441	Missense	proximal	-2	no	16.548	16.256	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	15.080	Down-regulation
TKL_LRRK_LRRK2_ST	Q5S007	LRRK2	Q5S007	LRRK2	S1444	G1451D	1451	Missense	distal	7	no	15.938	15.954	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	15.080	Up-regulation
TKL_LRRK_LRRK2_ST	Q5S007	LRRK2	Q5S007	LRRK2	S1444	A1442T	1442	Missense	proximal	-2	no	15.938	15.801	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	15.080	Down-regulation
TKL_LRRK_LRRK2_ST	Q5S007	LRRK2	Q5S007	LRRK2	S1444	R1441C	1441	Missense	distal	-3	no	15.938	16.249	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	15.080	Up-regulation
TKL_LRRK_LRRK2_ST	Q5S007	LRRK2	Q5S007	LRRK2	S1445	G1451D	1451	Missense	distal	6	no	15.500	15.052	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	15.080	Loss
TKL_LRRK_LRRK2_ST	Q5S007	LRRK2	Q5S007	LRRK2	S1445	A1442T	1442	Missense	distal	-3	no	15.500	15.363	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	15.080	Down-regulation
TKL_LRRK_LRRK2_ST	Q5S007	LRRK2	Q5S007	LRRK2	S1445	R1441C	1441	Missense	distal	-4	no	15.500	14.613	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	15.080	Loss
TKL_LRRK_LRRK2_ST	Q5S007	LRRK2	Q5S007	LRRK2	T1452	D1458N	1458	Missense	distal	6	no	16.299	16.202	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	15.080	Down-regulation
TKL_LRRK_LRRK2_ST	Q5S007	LRRK2	Q5S007	LRRK2	T1452	G1451D	1451	Missense	proximal	-1	no	16.299	14.146	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	15.080	Loss
TKL_LRRK_LRRK2_ST	Q5S007	LRRK2	Q5S007	LRRK2	T1452	S1457Y	1457	Missense	distal	5	no	16.299	16.563	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	15.080	Up-regulation
TKL_LRRK_LRRK2_ST	Q5S007	LRRK2	Q5S007	LRRK2	S1457	D1458N	1458	Missense	proximal	1	no	16.050	16.082	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	15.080	Up-regulation
TKL_LRRK_LRRK2_ST	Q5S007	LRRK2	Q5S007	LRRK2	S1457	R1462C	1462	Missense	distal	5	no	16.050	16.494	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	15.080	Up-regulation
TKL_LRRK_LRRK2_ST	Q5S007	LRRK2	Q5S007	LRRK2	S1457	G1451D	1451	Missense	distal	-6	no	16.050	17.295	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	15.080	Up-regulation
TKL_LRRK_LRRK2_ST	Q5S007	LRRK2	Q5S007	LRRK2	S1457	R1462H	1462	Missense	distal	5	no	16.050	16.111	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC;GDSC;CCLE	15.080	Up-regulation
TKL_LRRK_LRRK2_ST	Q5S007	LRRK2	Q5S007	LRRK2	S1457	A1464S	1464	Missense	distal	7	no	16.050	16.049	EPSD;PhosphoSitePlus	TCGA;ICGC	15.080	Down-regulation
TKL_LRRK_LRRK2_ST	Q5S007	LRRK2	Q5S007	LRRK2	S1457	S1457Y	1457	Missense	central	0	yes	16.050	0.000	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	15.080	Loss
TKL_LRRK_LRRK2_ST	Q5S007	LRRK2	Q5S007	LRRK2	S1467	E1472G	1472	Missense	distal	5	no	16.764	16.605	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	15.080	Down-regulation
TKL_LRRK_LRRK2_ST	Q5S007	LRRK2	Q5S007	LRRK2	S1467	R1462C	1462	Missense	distal	-5	no	16.764	16.620	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	15.080	Down-regulation
TKL_LRRK_LRRK2_ST	Q5S007	LRRK2	Q5S007	LRRK2	S1467	R1462H	1462	Missense	distal	-5	no	16.764	16.524	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC;GDSC;CCLE	15.080	Down-regulation
TKL_LRRK_LRRK2_ST	Q5S007	LRRK2	Q5S007	LRRK2	S1467	A1464S	1464	Missense	distal	-3	no	16.764	16.849	EPSD;PhosphoSitePlus	TCGA;ICGC	15.080	Up-regulation
TKL_LRRK_LRRK2_ST	Q5S007	LRRK2	Q5S007	LRRK2	S1467	S1467I	1467	Missense	central	0	yes	16.764	0.000	EPSD;PhosphoSitePlus	TCGA;ICGC	15.080	Loss
TKL_LRRK_LRRK2_ST	Q5S007	LRRK2	Q5S007	LRRK2	T1470	E1472G	1472	Missense	proximal	2	no	16.915	17.397	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	15.080	Up-regulation
TKL_LRRK_LRRK2_ST	Q5S007	LRRK2	Q5S007	LRRK2	T1470	R1477Q	1477	Missense	distal	7	no	16.915	16.902	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	15.080	Down-regulation
TKL_LRRK_LRRK2_ST	Q5S007	LRRK2	Q5S007	LRRK2	T1470	A1464S	1464	Missense	distal	-6	no	16.915	17.883	EPSD;PhosphoSitePlus	TCGA;ICGC	15.080	Up-regulation
TKL_LRRK_LRRK2_ST	Q5S007	LRRK2	Q5S007	LRRK2	T1470	S1467I	1467	Missense	distal	-3	no	16.915	16.839	EPSD;PhosphoSitePlus	TCGA;ICGC	15.080	Down-regulation
TKL_LRRK_LRRK2_ST	Q5S007	LRRK2	Q5S007	LRRK2	T1491	L1497F	1497	Missense	distal	6	no	17.116	16.115	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	15.080	Down-regulation
TKL_LRRK_LRRK2_ST	Q5S007	LRRK2	Q5S007	LRRK2	T1491	E1493K	1493	Missense	proximal	2	no	17.116	17.854	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	15.080	Up-regulation
TKL_LRRK_LRRK2_ST	Q5S007	LRRK2	Q5S007	LRRK2	T1503	E1507K	1507	Missense	distal	4	no	16.958	16.463	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	15.080	Down-regulation
TKL_LRRK_LRRK2_ST	Q5S007	LRRK2	Q5S007	LRRK2	T1503	R1501W	1501	Missense	proximal	-2	no	16.958	16.166	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC;GDSC	15.080	Down-regulation
TKL_LRRK_LRRK2_ST	Q5S007	LRRK2	Q5S007	LRRK2	T1503	L1497F	1497	Missense	distal	-6	no	16.958	17.151	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	15.080	Up-regulation
TKL_LRRK_LRRK2_ST	Q5S007	LRRK2	Q5S007	LRRK2	T1503	L1500P	1500	Missense	distal	-3	no	16.958	17.024	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	15.080	Up-regulation
TKL_LRRK_LRRK2_ST	Q5S007	LRRK2	Q5S007	LRRK2	S1508	E1507K	1507	Missense	proximal	-1	no	16.245	18.138	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	15.080	Up-regulation
TKL_LRRK_LRRK2_ST	Q5S007	LRRK2	Q5S007	LRRK2	S1508	R1501W	1501	Missense	distal	-7	no	16.245	14.266	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC;GDSC	15.080	Loss
TKL_LRRK_LRRK2_ST	Q5S007	LRRK2	Q5S007	LRRK2	S1508	I1513T	1513	Missense	distal	5	no	16.245	16.534	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	15.080	Up-regulation
TKL_LRRK_LRRK2_ST	Q5S007	LRRK2	Q5S007	LRRK2	S1508	F1511L	1511	Missense	distal	3	no	16.245	16.214	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	15.080	Down-regulation
TKL_LRRK_LRRK2_ST	Q5S007	LRRK2	Q5S007	LRRK2	S1647	K1640N	1640	Missense	distal	-7	no	16.945	16.873	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	15.080	Down-regulation
TKL_LRRK_LRRK2_ST	Q5S007	LRRK2	Q5S007	LRRK2	S1647	K1643N	1643	Missense	distal	-4	no	16.945	16.864	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	15.080	Down-regulation
TKL_LRRK_LRRK2_ST	Q5S007	LRRK2	Q5S007	LRRK2	S1647	M1646V	1646	Missense	proximal	-1	no	16.945	16.206	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	15.080	Down-regulation
TKL_LRRK_LRRK2_ST	Q5S007	LRRK2	Q5S007	LRRK2	S1647	M1646I	1646	Missense	proximal	-1	no	16.945	16.404	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	15.080	Down-regulation
TKL_LRRK_LRRK2_ST	Q5S007	LRRK2	Q5S007	LRRK2	S1721	S1721L	1721	Missense	central	0	yes	15.528	0.000	EPSD	TCGA;ICGC;COSMIC	15.080	Loss
TKL_LRRK_LRRK2_ST	Q5S007	LRRK2	Q5S007	LRRK2	S1721	E1714Q	1714	Missense	distal	-7	no	15.528	15.915	EPSD	TCGA;ICGC;COSMIC	15.080	Up-regulation
TKL_LRRK_LRRK2_ST	Q5S007	LRRK2	Q5S007	LRRK2	S1721	R1728H	1728	Missense	distal	7	no	15.528	15.617	EPSD	TCGA;ICGC;COSMIC	15.080	Up-regulation
TKL_LRRK_LRRK2_ST	Q5S007	LRRK2	Q5S007	LRRK2	S1721	G1722R	1722	Missense	proximal	1	no	15.528	15.829	EPSD	TCGA;ICGC;COSMIC	15.080	Up-regulation
TKL_LRRK_LRRK2_ST	Q5S007	LRRK2	Q5S007	LRRK2	T1849	S1853Y	1853	Missense	distal	4	no	17.939	15.997	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	15.080	Down-regulation
TKL_LRRK_LRRK2_ST	Q5S007	LRRK2	Q5S007	LRRK2	S1853	S1853Y	1853	Missense	central	0	yes	17.287	0.000	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	15.080	Loss
TKL_LRRK_LRRK2_ST	Q5S007	LRRK2	Q5S007	LRRK2	T1912	V1905A	1905	Missense	distal	-7	no	17.371	17.234	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	15.080	Down-regulation
TKL_LRRK_LRRK2_ST	Q5S007	LRRK2	Q5S007	LRRK2	T1912	S1913P	1913	Missense	proximal	1	no	17.371	17.542	EPSD;PhosphoSitePlus	TCGA;ICGC	15.080	Up-regulation
TKL_LRRK_LRRK2_ST	Q5S007	LRRK2	Q5S007	LRRK2	S1913	S1913P	1913	Missense	central	0	yes	19.825	0.000	EPSD;PhosphoSitePlus	TCGA;ICGC	15.080	Loss
TKL_LRRK_LRRK2_ST	Q5S007	LRRK2	Q5S007	LRRK2	T1967	Q1960K	1960	Missense	distal	-7	no	17.155	18.182	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	15.080	Up-regulation
TKL_LRRK_LRRK2_ST	Q5S007	LRRK2	Q5S007	LRRK2	T1969	T1967S	1967	Missense	proximal	-2	no	18.241	18.540	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	15.080	Up-regulation
TKL_LRRK_LRRK2_ST	Q5S007	LRRK2	Q5S007	LRRK2	T2031	E2033K	2033	Missense	proximal	2	no	18.012	18.750	PhosphoSitePlus;EPSD	TCGA;ICGC	15.080	Up-regulation
TKL_LRRK_LRRK2_ST	Q5S007	LRRK2	Q5S007	LRRK2	T2035	R2039C	2039	Missense	distal	4	no	16.598	15.996	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	15.080	Down-regulation
TKL_LRRK_LRRK2_ST	Q5S007	LRRK2	Q5S007	LRRK2	T2035	E2033K	2033	Missense	proximal	-2	no	16.598	16.827	EPSD;PhosphoSitePlus	TCGA;ICGC	15.080	Up-regulation
TKL_LRRK_LRRK2_ST	Q5S007	LRRK2	Q5S007	LRRK2	T2237	E2230K	2230	Missense	distal	-7	no	14.120	15.535	EPSD	TCGA;ICGC;COSMIC	15.080	Gain
TKL_LRRK_LRRK2_ST	Q5S007	LRRK2	Q5S007	LRRK2	S2257	N2261H	2261	Missense	distal	4	no	17.369	17.049	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	15.080	Down-regulation
TKL_LRRK_LRRK2_ST	Q5S007	LRRK2	Q5S007	LRRK2	S2257	S2254F	2254	Missense	distal	-3	no	17.369	17.273	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	15.080	Down-regulation
TKL_LRRK_LRRK2_ST	Q5S007	LRRK2	Q5S007	LRRK2	S2257	F2262L	2262	Missense	distal	5	no	17.369	16.685	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	15.080	Down-regulation
TKL_LRRK_LRRK2_ST	Q5S007	LRRK2	Q5S007	LRRK2	S2257	F2262Y	2262	Missense	distal	5	no	17.369	16.962	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	15.080	Down-regulation
TKL_LRRK_LRRK2_ST	Q5S007	LRRK2	Q5S007	LRRK2	S2257	L2263I	2263	Missense	distal	6	no	17.369	17.229	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	15.080	Down-regulation
TKL_LRRK_LRRK2_ST	Q5S007	LRRK2	Q5S007	LRRK2	S2257	F2262V	2262	Missense	distal	5	no	17.369	17.396	EPSD;PhosphoSitePlus	TCGA	15.080	Up-regulation
TKL_LRRK_LRRK2_ST	Q5S007	LRRK2	Q5S007	LRRK2	T2483	R2477Q	2477	Missense	distal	-6	no	19.727	19.696	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	15.080	Down-regulation
TKL_LRRK_LRRK2_ST	Q5S007	LRRK2	Q5S007	LRRK2	T2483	Q2490L	2490	Missense	distal	7	no	19.727	19.769	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	15.080	Up-regulation
TKL_LRRK_LRRK2_ST	Q5S007	LRRK2	Q5S007	LRRK2	T2483	E2488K	2488	Missense	distal	5	no	19.727	19.684	EPSD;PhosphoSitePlus	TCGA	15.080	Down-regulation
TKL_LRRK_LRRK2_ST	P15311	EZR	Q5S007	LRRK2	T533	L538V	538	Missense	distal	5	no	14.373	15.084	EPSD	TCGA;ICGC;COSMIC	15.080	Gain
TKL_LRRK_LRRK2_ST	P15311	EZR	Q5S007	LRRK2	S536	A541V	541	Missense	distal	5	no	14.853	15.185	EPSD	TCGA;ICGC;COSMIC	15.080	Gain
TKL_LRRK_LRRK2_ST	P15311	EZR	Q5S007	LRRK2	T548	N550K	550	Missense	proximal	2	no	14.807	15.625	EPSD	TCGA;ICGC;COSMIC	15.080	Gain
TKL_LRRK_LRRK2_ST	P04637	TP53	Q5S007	LRRK2	S106	L111R	111	Missense	distal	5	no	15.023	15.238	EPSD	TCGA;ICGC;COSMIC	15.080	Gain
TKL_LRRK_LRRK2_ST	P04637	TP53	Q5S007	LRRK2	S106	L111P	111	Missense	distal	5	no	15.023	15.524	EPSD	TCGA;ICGC;COSMIC	15.080	Gain
TKL_LRRK_LRRK2_ST	P04637	TP53	Q5S007	LRRK2	S106	G105R	105	Missense	proximal	-1	no	15.023	15.334	EPSD	TCGA;ICGC;COSMIC;CCLE	15.080	Gain
TKL_LRRK_LRRK2_ST	P04637	TP53	Q5S007	LRRK2	T304	A307V	307	Missense	distal	3	no	17.200	17.015	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC;GDSC	15.080	Down-regulation
TKL_LRRK_LRRK2_ST	P04637	TP53	Q5S007	LRRK2	T377	S376C	376	Missense	proximal	-1	no	15.470	14.785	PhosphoSitePlus;EPSD	TCGA;ICGC;COSMIC	15.080	Loss
TKL_LRRK_LRRK2_ST	P04637	TP53	Q5S007	LRRK2	T377	Q375K	375	Missense	proximal	-2	no	15.470	15.596	PhosphoSitePlus;EPSD	TCGA;ICGC;COSMIC	15.080	Up-regulation
TKL_LRRK_LRRK2_ST	P62280	RPS11	Q5S007	LRRK2	T28	K32T	32	Missense	distal	4	no	16.306	16.063	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	15.080	Down-regulation
TKL_LRRK_LRRK2_ST	P62280	RPS11	Q5S007	LRRK2	T46	I51M	51	Missense	distal	5	no	18.909	18.672	PhosphoSitePlus;EPSD	TCGA;ICGC;COSMIC	15.080	Down-regulation
TKL_LRRK_LRRK2_ST	P62280	RPS11	Q5S007	LRRK2	T54	I51M	51	Missense	distal	-3	no	18.314	18.045	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	15.080	Down-regulation
TKL_LRRK_LRRK2_ST	P62280	RPS11	Q5S007	LRRK2	T78	R84G	84	Missense	distal	6	no	15.774	15.907	EPSD	TCGA;ICGC;COSMIC	15.080	Up-regulation
TKL_LRRK_LRRK2_ST	P62280	RPS11	Q5S007	LRRK2	T78	R71W	71	Missense	distal	-7	no	15.774	13.795	EPSD	TCGA;ICGC;COSMIC	15.080	Loss
TKL_LRRK_LRRK2_ST	P61020	RAB5B	Q5S007	LRRK2	S29	E28K	28	Missense	proximal	-1	no	13.315	15.208	EPSD	TCGA;ICGC;COSMIC	15.080	Gain
TKL_LRRK_LRRK2_ST	Q99683	MAP3K5	Q5S007	LRRK2	T825	K819N	819	Missense	distal	-6	no	17.293	17.555	EPSD;PhosphoSitePlus	TCGA;COSMIC	15.080	Up-regulation
TKL_LRRK_LRRK2_ST	Q99683	MAP3K5	Q5S007	LRRK2	T838	F839C	839	Missense	proximal	1	no	16.795	16.583	PhosphoSitePlus;EPSD	TCGA	15.080	Down-regulation
TKL_LRRK_LRRK2_ST	Q99683	MAP3K5	Q5S007	LRRK2	S908	F914L	914	Missense	distal	6	no	16.292	17.294	EPSD	TCGA;COSMIC	15.080	Up-regulation
TKL_LRRK_LRRK2_ST	Q99683	MAP3K5	Q5S007	LRRK2	S908	P901L	901	Missense	distal	-7	no	16.292	14.973	EPSD	TCGA;COSMIC	15.080	Loss
TKL_LRRK_LRRK2_ST	Q99683	MAP3K5	Q5S007	LRRK2	S908	A913S	913	Missense	distal	5	no	16.292	15.925	EPSD	TCGA;COSMIC	15.080	Down-regulation
TKL_LRRK_LRRK2_ST	Q99683	MAP3K5	Q5S007	LRRK2	S1039	D1038Y	1038	Missense	proximal	-1	no	14.132	15.490	EPSD	TCGA;COSMIC	15.080	Gain
TKL_LRRK_LRRK2_ST	Q99683	MAP3K5	Q5S007	LRRK2	S1157	D1156H	1156	Missense	proximal	-1	no	14.311	16.012	EPSD	TCGA;ICGC;COSMIC	15.080	Gain
TKL_LRRK_LRRK2_ST	P46459	NSF	Q5S007	LRRK2	T344	T344M	344	Missense	central	0	yes	15.438	0.000	EPSD	TCGA;COSMIC	15.080	Loss
TKL_LRRK_LRRK2_ST	P46459	NSF	Q5S007	LRRK2	T344	G345A	345	Missense	proximal	1	no	15.438	15.538	EPSD	TCGA;COSMIC	15.080	Up-regulation
TKL_LRRK_LRRK2_ST	P46459	NSF	Q5S007	LRRK2	S356	N352Y	352	Missense	distal	-4	no	16.040	13.827	EPSD	TCGA;COSMIC	15.080	Loss
TKL_LRRK_LRRK2_ST	P46459	NSF	Q5S007	LRRK2	T579	F576L	576	Missense	distal	-3	no	15.586	15.613	EPSD	TCGA;COSMIC	15.080	Up-regulation
TKL_LRRK_LRRK2_ST	P46459	NSF	Q5S007	LRRK2	T645	K639N	639	Missense	distal	-6	no	18.553	18.815	PhosphoSitePlus	TCGA;COSMIC	15.080	Up-regulation
TKL_LRRK_LRRK2_ST	P46459	NSF	Q5S007	LRRK2	T645	T645I	645	Missense	central	0	yes	18.553	0.000	PhosphoSitePlus	TCGA;COSMIC	15.080	Loss
TKL_LRRK_LRRK2_ST	P46459	NSF	Q5S007	LRRK2	T693	F686V	686	Missense	distal	-7	no	16.279	16.708	EPSD	TCGA;COSMIC	15.080	Up-regulation
TKL_LRRK_LRRK2_ST	P46459	NSF	Q5S007	LRRK2	T693	R691H	691	Missense	proximal	-2	no	16.279	16.496	EPSD	TCGA	15.080	Up-regulation
TKL_LRRK_LRRK2_ST	P62841	RPS15	Q5S007	LRRK2	T78	R81Q	81	Missense	distal	3	no	15.564	15.520	EPSD	TCGA;COSMIC	15.080	Down-regulation
TKL_LRRK_LRRK2_ST	P26038	MSN	Q5S007	LRRK2	S127	T121A	121	Missense	distal	-6	no	13.785	15.312	EPSD	TCGA;ICGC;COSMIC	15.080	Gain
TKL_LRRK_LRRK2_ST	P26038	MSN	Q5S007	LRRK2	S527	H521N	521	Missense	distal	-6	no	14.328	15.285	EPSD	TCGA;ICGC;COSMIC	15.080	Gain
TKL_LRRK_LRRK2_ST	P26038	MSN	Q5S007	LRRK2	T539	D534Y	534	Missense	distal	-5	no	15.538	15.517	EPSD	TCGA;ICGC;COSMIC	15.080	Down-regulation
TKL_LRRK_LRRK2_ST	P26038	MSN	Q5S007	LRRK2	T539	H545N	545	Missense	distal	6	no	15.538	15.646	EPSD	TCGA;ICGC;COSMIC	15.080	Up-regulation
TKL_LRRK_LRRK2_ST	P26038	MSN	Q5S007	LRRK2	T539	A532D	532	Missense	distal	-7	no	15.538	15.783	EPSD	TCGA;ICGC;COSMIC	15.080	Up-regulation
TKL_LRRK_LRRK2_ST	P10636	MAPT	Q5S007	LRRK2	S68	A72V	72	Missense	distal	4	no	15.057	15.103	EPSD	TCGA;ICGC;COSMIC	15.080	Gain
TKL_LRRK_LRRK2_ST	P10636	MAPT	Q5S007	LRRK2	S68	A66S	66	Missense	proximal	-2	no	15.057	15.219	EPSD	TCGA;ICGC;COSMIC	15.080	Gain
TKL_LRRK_LRRK2_ST	P10636	MAPT	Q5S007	LRRK2	T111	E117K	117	Missense	distal	6	no	17.258	17.133	EPSD	TCGA;ICGC;COSMIC	15.080	Down-regulation
TKL_LRRK_LRRK2_ST	P10636	MAPT	Q5S007	LRRK2	T111	A118V	118	Missense	distal	7	no	17.258	17.228	EPSD	TCGA;ICGC;COSMIC	15.080	Down-regulation
TKL_LRRK_LRRK2_ST	P10636	MAPT	Q5S007	LRRK2	T416	P415L	415	Missense	proximal	-1	no	14.926	15.463	EPSD	TCGA;ICGC;COSMIC	15.080	Gain
TKL_LRRK_LRRK2_ST	P10636	MAPT	Q5S007	LRRK2	S420	P415L	415	Missense	distal	-5	no	15.236	15.245	EPSD	TCGA;ICGC;COSMIC	15.080	Up-regulation
TKL_LRRK_LRRK2_ST	P10636	MAPT	Q5S007	LRRK2	S447	K440E	440	Missense	distal	-7	no	15.455	14.040	EPSD	TCGA;ICGC;COSMIC	15.080	Loss
TKL_LRRK_LRRK2_ST	P10636	MAPT	Q5S007	LRRK2	S447	S452C	452	Missense	distal	5	no	15.455	16.101	EPSD	TCGA;ICGC;COSMIC	15.080	Up-regulation
TKL_LRRK_LRRK2_ST	P10636	MAPT	Q5S007	LRRK2	S447	S443F	443	Missense	distal	-4	no	15.455	15.988	EPSD	TCGA;ICGC;COSMIC	15.080	Up-regulation
TKL_LRRK_LRRK2_ST	P10636	MAPT	Q5S007	LRRK2	S447	S444F	444	Missense	distal	-3	no	15.455	15.359	EPSD	TCGA;ICGC	15.080	Down-regulation
TKL_LRRK_LRRK2_ST	P10636	MAPT	Q5S007	LRRK2	S447	S452Y	452	Missense	distal	5	no	15.455	15.720	EPSD	TCGA;ICGC;COSMIC	15.080	Up-regulation
TKL_LRRK_LRRK2_ST	P10636	MAPT	Q5S007	LRRK2	T466	R472Q	472	Missense	distal	6	no	17.500	18.014	EPSD	TCGA	15.080	Up-regulation
TKL_LRRK_LRRK2_ST	P10636	MAPT	Q5S007	LRRK2	T466	R472W	472	Missense	distal	6	no	17.500	16.989	EPSD	TCGA;COSMIC	15.080	Down-regulation
TKL_LRRK_LRRK2_ST	P10636	MAPT	Q5S007	LRRK2	T466	L459R	459	Missense	distal	-7	no	17.500	19.129	EPSD	TCGA;ICGC;COSMIC	15.080	Up-regulation
TKL_LRRK_LRRK2_ST	P10636	MAPT	Q5S007	LRRK2	T466	L459F	459	Missense	distal	-7	no	17.500	18.376	EPSD	TCGA;ICGC	15.080	Up-regulation
TKL_LRRK_LRRK2_ST	P05067	APP	Q5S007	LRRK2	T280	T274A	274	Missense	distal	-6	no	13.844	15.372	EPSD	TCGA;COSMIC;CCLE	15.080	Gain
TKL_LRRK_LRRK2_ST	P05067	APP	Q5S007	LRRK2	T381	E380K	380	Missense	proximal	-1	no	16.467	18.360	EPSD	TCGA;COSMIC;CCLE	15.080	Up-regulation
TKL_LRRK_LRRK2_ST	P05067	APP	Q5S007	LRRK2	S441	S441Y	441	Missense	central	0	yes	16.391	0.000	EPSD	TCGA;COSMIC	15.080	Loss
TKL_LRRK_LRRK2_ST	P05067	APP	Q5S007	LRRK2	S441	F435S	435	Missense	distal	-6	no	16.391	16.865	EPSD	TCGA	15.080	Up-regulation
TKL_LRRK_LRRK2_ST	P05067	APP	Q5S007	LRRK2	T743	R747P	747	Missense	distal	4	no	16.869	14.930	PhosphoSitePlus	TCGA;COSMIC	15.080	Loss
TKL_LRRK_LRRK2_ST	P05067	APP	Q5S007	LRRK2	T743	R747C	747	Missense	distal	4	no	16.869	16.267	PhosphoSitePlus	TCGA;COSMIC;GDSC	15.080	Down-regulation
TKL_LRRK_LRRK2_ST	P05067	APP	Q5S007	LRRK2	T743	R747H	747	Missense	distal	4	no	16.869	16.011	PhosphoSitePlus	TCGA;COSMIC	15.080	Down-regulation
TKL_LRRK_LRRK2_ST	Q13501	SQSTM1	Q5S007	LRRK2	S88	S88P	88	Missense	central	0	yes	16.466	0.000	EPSD	TCGA;ICGC;COSMIC	15.080	Loss
TKL_LRRK_LRRK2_ST	Q13501	SQSTM1	Q5S007	LRRK2	T138	S143C	143	Missense	distal	5	no	15.898	16.544	PhosphoSitePlus	TCGA;ICGC;COSMIC	15.080	Up-regulation
TKL_LRRK_LRRK2_ST	Q13501	SQSTM1	Q5S007	LRRK2	T138	R139H	139	Missense	proximal	1	no	15.898	15.700	PhosphoSitePlus	TCGA;ICGC;COSMIC	15.080	Down-regulation
TKL_LRRK_LRRK2_ST	Q13501	SQSTM1	Q5S007	LRRK2	T164	R161W	161	Missense	distal	-3	no	17.232	17.906	EPSD	TCGA;ICGC;COSMIC	15.080	Up-regulation
TKL_LRRK_LRRK2_ST	Q13501	SQSTM1	Q5S007	LRRK2	T221	P228L	228	Missense	distal	7	no	15.108	15.082	EPSD	TCGA;COSMIC	15.080	Down-regulation
TKL_LRRK_LRRK2_ST	Q13501	SQSTM1	Q5S007	LRRK2	S276	S277G	277	Missense	proximal	1	no	15.308	15.304	EPSD	TCGA;ICGC;COSMIC	15.080	Down-regulation
TKL_LRRK_LRRK2_ST	Q13501	SQSTM1	Q5S007	LRRK2	S276	S276Y	276	Missense	central	0	yes	15.308	0.000	EPSD	TCGA;ICGC	15.080	Loss
TKL_LRRK_LRRK2_ST	Q13501	SQSTM1	Q5S007	LRRK2	S276	S277I	277	Missense	proximal	1	no	15.308	15.526	EPSD	TCGA;ICGC	15.080	Up-regulation
CAMK_CAMKL_QIK_SIK1_ST	Q9Y618	NCOR2	P57059	SIK1	S140	D138Y	138	Missense	proximal	-2	no	6.096	7.152	EPSD	TCGA;ICGC;COSMIC	6.412	Gain
CAMK_CAMKL_QIK_SIK1_ST	Q9Y618	NCOR2	P57059	SIK1	S373	G378C	378	Missense	distal	5	no	6.811	7.001	EPSD	TCGA;ICGC;COSMIC	6.412	Up-regulation
CAMK_CAMKL_QIK_SIK1_ST	Q9Y618	NCOR2	P57059	SIK1	S373	D377N	377	Missense	distal	4	no	6.811	6.790	EPSD	TCGA;ICGC	6.412	Down-regulation
CAMK_CAMKL_QIK_SIK1_ST	Q9Y618	NCOR2	P57059	SIK1	S433	W432C	432	Missense	proximal	-1	no	7.081	7.237	EPSD	TCGA;ICGC;COSMIC	6.412	Up-regulation
CAMK_CAMKL_QIK_SIK1_ST	Q9Y618	NCOR2	P57059	SIK1	S493	R488Q	488	Missense	distal	-5	no	5.997	6.964	EPSD	TCGA;COSMIC	6.412	Gain
CAMK_CAMKL_QIK_SIK1_ST	Q9Y618	NCOR2	P57059	SIK1	S585	S592N	592	Missense	distal	7	no	8.370	8.076	EPSD	TCGA;COSMIC	6.412	Down-regulation
CAMK_CAMKL_QIK_SIK1_ST	Q9Y618	NCOR2	P57059	SIK1	S592	Q599H	599	Missense	distal	7	no	7.228	7.186	EPSD	TCGA;COSMIC	6.412	Down-regulation
CAMK_CAMKL_QIK_SIK1_ST	Q9Y618	NCOR2	P57059	SIK1	S592	S592N	592	Missense	central	0	yes	7.228	0.000	EPSD	TCGA;COSMIC	6.412	Loss
CAMK_CAMKL_QIK_SIK1_ST	Q9Y618	NCOR2	P57059	SIK1	S601	E608D	608	Missense	distal	7	no	6.617	6.504	EPSD	TCGA;COSMIC	6.412	Down-regulation
CAMK_CAMKL_QIK_SIK1_ST	Q9Y618	NCOR2	P57059	SIK1	S601	E608A	608	Missense	distal	7	no	6.617	6.589	EPSD	TCGA;COSMIC	6.412	Down-regulation
CAMK_CAMKL_QIK_SIK1_ST	Q9Y618	NCOR2	P57059	SIK1	S601	Q599H	599	Missense	proximal	-2	no	6.617	6.346	EPSD	TCGA;COSMIC	6.412	Loss
CAMK_CAMKL_QIK_SIK1_ST	Q9Y618	NCOR2	P57059	SIK1	T867	V862I	862	Missense	distal	-5	no	8.219	8.697	EPSD	TCGA;COSMIC	6.412	Up-regulation
CAMK_CAMKL_QIK_SIK1_ST	Q9Y618	NCOR2	P57059	SIK1	T867	E860K	860	Missense	distal	-7	no	8.219	8.001	EPSD	TCGA;COSMIC	6.412	Down-regulation
CAMK_CAMKL_QIK_SIK1_ST	Q9Y618	NCOR2	P57059	SIK1	T867	P861L	861	Missense	distal	-6	no	8.219	8.306	EPSD	TCGA;COSMIC	6.412	Up-regulation
CAMK_CAMKL_QIK_SIK1_ST	Q9Y618	NCOR2	P57059	SIK1	T867	P874A	874	Missense	distal	7	no	8.219	8.426	EPSD	TCGA;COSMIC	6.412	Up-regulation
CAMK_CAMKL_QIK_SIK1_ST	Q9Y618	NCOR2	P57059	SIK1	T867	E871K	871	Missense	distal	4	no	8.219	8.239	EPSD	TCGA;COSMIC	6.412	Up-regulation
CAMK_CAMKL_QIK_SIK1_ST	Q9Y618	NCOR2	P57059	SIK1	T867	S864R	864	Missense	distal	-3	no	8.219	9.396	EPSD	TCGA;COSMIC	6.412	Up-regulation
CAMK_CAMKL_QIK_SIK1_ST	Q9Y618	NCOR2	P57059	SIK1	S943	R936L	936	Missense	distal	-7	no	5.983	6.880	EPSD	TCGA;COSMIC	6.412	Gain
CAMK_CAMKL_QIK_SIK1_ST	Q9Y618	NCOR2	P57059	SIK1	S1018	R1020Q	1020	Missense	proximal	2	no	9.929	9.954	EPSD	TCGA;COSMIC	6.412	Up-regulation
CAMK_CAMKL_QIK_SIK1_ST	Q9Y618	NCOR2	P57059	SIK1	T1594	S1595F	1595	Missense	proximal	1	no	7.007	6.472	EPSD	TCGA;COSMIC	6.412	Down-regulation
CAMK_CAMKL_QIK_SIK1_ST	Q9Y618	NCOR2	P57059	SIK1	S1595	S1595F	1595	Missense	central	0	yes	8.540	0.000	EPSD	TCGA;COSMIC	6.412	Loss
CAMK_CAMKL_QIK_SIK1_ST	Q9Y618	NCOR2	P57059	SIK1	T1596	S1595F	1595	Missense	proximal	-1	no	10.256	9.978	EPSD	TCGA;COSMIC	6.412	Down-regulation
CAMK_CAMKL_QIK_SIK1_ST	Q9Y618	NCOR2	P57059	SIK1	S1783	L1785F	1785	Missense	proximal	2	no	8.658	8.733	EPSD	TCGA;COSMIC	6.412	Up-regulation
CAMK_CAMKL_QIK_SIK1_ST	Q9Y618	NCOR2	P57059	SIK1	T1798	R1804W	1804	Missense	distal	6	no	7.353	7.114	EPSD	TCGA;CCLE	6.412	Down-regulation
CMGC_MAPK_p38_MAPK14_ST	P49023	PXN	Q16539	MAPK14	T29	E27G	27	Missense	proximal	-2	no	12.441	11.763	EPSD	TCGA	5.915	Down-regulation
CMGC_MAPK_p38_MAPK14_ST	P49023	PXN	Q16539	MAPK14	S130	M134I	134	Missense	distal	4	no	9.787	9.322	EPSD	TCGA;COSMIC	5.915	Down-regulation
CMGC_MAPK_p38_MAPK14_ST	P49023	PXN	Q16539	MAPK14	S130	E128K	128	Missense	proximal	-2	no	9.787	8.756	EPSD	TCGA;COSMIC	5.915	Down-regulation
CMGC_MAPK_p38_MAPK14_ST	P49023	PXN	Q16539	MAPK14	S130	Q124H	124	Missense	distal	-6	no	9.787	9.494	EPSD	TCGA;COSMIC	5.915	Down-regulation
CMGC_MAPK_p38_MAPK14_ST	P49023	PXN	Q16539	MAPK14	S188	S188N	188	Missense	central	0	yes	10.832	0.000	EPSD	TCGA	5.915	Loss
CMGC_MAPK_p38_MAPK14_ST	P49023	PXN	Q16539	MAPK14	S230	S227F	227	Missense	distal	-3	no	10.238	7.531	EPSD	TCGA;COSMIC	5.915	Down-regulation
CMGC_MAPK_p38_MAPK14_ST	P49023	PXN	Q16539	MAPK14	S230	V237A	237	Missense	distal	7	no	10.238	10.347	EPSD	TCGA	5.915	Up-regulation
CMGC_MAPK_p38_MAPK14_ST	P49023	PXN	Q16539	MAPK14	T236	V237A	237	Missense	proximal	1	no	3.322	6.282	EPSD	TCGA	5.915	Gain
CMGC_MAPK_p38_MAPK14_ST	P49023	PXN	Q16539	MAPK14	S244	V248I	248	Missense	distal	4	no	9.196	9.147	EPSD	TCGA;COSMIC;CCLE	5.915	Down-regulation
CMGC_MAPK_p38_MAPK14_ST	P49023	PXN	Q16539	MAPK14	S244	R247H	247	Missense	distal	3	no	9.196	9.267	EPSD	TCGA;COSMIC	5.915	Up-regulation
CMGC_MAPK_p38_MAPK14_ST	P49023	PXN	Q16539	MAPK14	S244	V237A	237	Missense	distal	-7	no	9.196	10.014	EPSD	TCGA	5.915	Up-regulation
CMGC_MAPK_p38_MAPK14_ST	Q13155	AIMP2	Q16539	MAPK14	S130	P131L	131	Missense	proximal	1	no	11.674	3.624	EPSD	TCGA	5.915	Loss
CMGC_MAPK_p38_MAPK14_ST	Q13155	AIMP2	Q16539	MAPK14	S130	P128L	128	Missense	proximal	-2	no	11.674	10.294	EPSD	TCGA;COSMIC	5.915	Down-regulation
CMGC_MAPK_p38_MAPK14_ST	Q13155	AIMP2	Q16539	MAPK14	S130	A126T	126	Missense	distal	-4	no	11.674	11.911	EPSD	TCGA;COSMIC	5.915	Up-regulation
CMGC_MAPK_p38_MAPK14_ST	Q13155	AIMP2	Q16539	MAPK14	S130	V123M	123	Missense	distal	-7	no	11.674	12.364	EPSD	TCGA	5.915	Up-regulation
CMGC_MAPK_p38_MAPK14_ST	Q13155	AIMP2	Q16539	MAPK14	S156	H153Y	153	Missense	distal	-3	no	8.414	8.760	PhosphoSitePlus	TCGA;COSMIC	5.915	Up-regulation
CMGC_MAPK_p38_MAPK14_ST	Q13155	AIMP2	Q16539	MAPK14	S156	S156F	156	Missense	central	0	yes	8.414	0.000	PhosphoSitePlus	TCGA;COSMIC	5.915	Loss
CMGC_MAPK_p38_MAPK14_ST	Q02078	MEF2A	Q16539	MAPK14	S98	D100Y	100	Missense	proximal	2	no	10.930	11.090	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	5.915	Up-regulation
CMGC_MAPK_p38_MAPK14_ST	Q02078	MEF2A	Q16539	MAPK14	S181	L180F	180	Missense	proximal	-1	no	13.783	13.747	EPSD	TCGA;ICGC;COSMIC	5.915	Down-regulation
CMGC_MAPK_p38_MAPK14_ST	Q02078	MEF2A	Q16539	MAPK14	S192	P196S	196	Missense	distal	4	no	11.537	11.977	PhosphoSitePlus;EPSD	TCGA;COSMIC	5.915	Up-regulation
CMGC_MAPK_p38_MAPK14_ST	Q02078	MEF2A	Q16539	MAPK14	S192	S192F	192	Missense	central	0	yes	11.537	0.000	PhosphoSitePlus;EPSD	TCGA;COSMIC	5.915	Loss
CMGC_MAPK_p38_MAPK14_ST	Q02078	MEF2A	Q16539	MAPK14	S201	T202N	202	Missense	proximal	1	no	7.387	7.036	EPSD	TCGA;ICGC;COSMIC	5.915	Down-regulation
CMGC_MAPK_p38_MAPK14_ST	Q02078	MEF2A	Q16539	MAPK14	S201	P196S	196	Missense	distal	-5	no	7.387	6.939	EPSD	TCGA;COSMIC	5.915	Down-regulation
CMGC_MAPK_p38_MAPK14_ST	Q02078	MEF2A	Q16539	MAPK14	S223	G219A	219	Missense	distal	-4	no	11.196	11.238	EPSD;PhosphoSitePlus	TCGA;COSMIC	5.915	Up-regulation
CMGC_MAPK_p38_MAPK14_ST	Q02078	MEF2A	Q16539	MAPK14	S223	F229C	229	Missense	distal	6	no	11.196	11.278	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	5.915	Up-regulation
CMGC_MAPK_p38_MAPK14_ST	Q02078	MEF2A	Q16539	MAPK14	S235	S235F	235	Missense	central	0	yes	11.534	0.000	EPSD	TCGA;ICGC;COSMIC	5.915	Loss
CMGC_MAPK_p38_MAPK14_ST	Q02078	MEF2A	Q16539	MAPK14	S235	F229C	229	Missense	distal	-6	no	11.534	12.006	EPSD	TCGA;ICGC;COSMIC	5.915	Up-regulation
CMGC_MAPK_p38_MAPK14_ST	Q02078	MEF2A	Q16539	MAPK14	S235	N237K	237	Missense	proximal	2	no	11.534	11.441	EPSD	TCGA;COSMIC	5.915	Down-regulation
CMGC_MAPK_p38_MAPK14_ST	Q02078	MEF2A	Q16539	MAPK14	S255	G260V	260	Missense	distal	5	no	10.492	10.090	EPSD	TCGA;ICGC;COSMIC	5.915	Down-regulation
CMGC_MAPK_p38_MAPK14_ST	Q02078	MEF2A	Q16539	MAPK14	S255	P258A	258	Missense	distal	3	no	10.492	10.466	EPSD	TCGA;COSMIC	5.915	Down-regulation
CMGC_MAPK_p38_MAPK14_ST	Q02078	MEF2A	Q16539	MAPK14	S255	P257L	257	Missense	proximal	2	no	10.492	10.380	EPSD	TCGA;COSMIC	5.915	Down-regulation
CMGC_MAPK_p38_MAPK14_ST	P04150	NR3C1	Q16539	MAPK14	T8	P9H	9	Missense	proximal	1	no	12.176	-1.478	EPSD	TCGA;COSMIC	5.915	Loss
CMGC_MAPK_p38_MAPK14_ST	P04150	NR3C1	Q16539	MAPK14	S45	A51T	51	Missense	distal	6	no	10.868	10.850	EPSD	TCGA;ICGC;COSMIC	5.915	Down-regulation
CMGC_MAPK_p38_MAPK14_ST	P04150	NR3C1	Q16539	MAPK14	S45	S42Y	42	Missense	distal	-3	no	10.868	9.973	EPSD	TCGA;ICGC;COSMIC	5.915	Down-regulation
CMGC_MAPK_p38_MAPK14_ST	P04150	NR3C1	Q16539	MAPK14	S47	Q53E	53	Missense	distal	6	no	7.746	7.815	EPSD	TCGA;ICGC;COSMIC	5.915	Up-regulation
CMGC_MAPK_p38_MAPK14_ST	P04150	NR3C1	Q16539	MAPK14	S47	A51T	51	Missense	distal	4	no	7.746	7.791	EPSD	TCGA;ICGC;COSMIC	5.915	Up-regulation
CMGC_MAPK_p38_MAPK14_ST	P04150	NR3C1	Q16539	MAPK14	S47	S42Y	42	Missense	distal	-5	no	7.746	8.195	EPSD	TCGA;ICGC;COSMIC	5.915	Up-regulation
CMGC_MAPK_p38_MAPK14_ST	P04150	NR3C1	Q16539	MAPK14	T133	P136L	136	Missense	distal	3	no	6.481	6.515	EPSD	TCGA;ICGC;COSMIC	5.915	Up-regulation
CMGC_MAPK_p38_MAPK14_ST	P04150	NR3C1	Q16539	MAPK14	T133	K140N	140	Missense	distal	7	no	6.481	6.672	EPSD	TCGA;ICGC;COSMIC	5.915	Up-regulation
CMGC_MAPK_p38_MAPK14_ST	P04150	NR3C1	Q16539	MAPK14	S144	K140N	140	Missense	distal	-4	no	6.120	6.267	EPSD	TCGA;ICGC;COSMIC	5.915	Up-regulation
CMGC_MAPK_p38_MAPK14_ST	P04150	NR3C1	Q16539	MAPK14	S148	E153K	153	Missense	distal	5	no	6.149	5.582	EPSD	TCGA;ICGC;COSMIC	5.915	Loss
CMGC_MAPK_p38_MAPK14_ST	P04150	NR3C1	Q16539	MAPK14	S211	P212H	212	Missense	proximal	1	no	10.702	-2.952	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	5.915	Loss
CMGC_MAPK_p38_MAPK14_ST	P04150	NR3C1	Q16539	MAPK14	S226	N222T	222	Missense	distal	-4	no	9.180	9.385	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	5.915	Up-regulation
CMGC_MAPK_p38_MAPK14_ST	P04150	NR3C1	Q16539	MAPK14	S226	A229V	229	Missense	distal	3	no	9.180	9.208	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	5.915	Up-regulation
CMGC_MAPK_p38_MAPK14_ST	P04150	NR3C1	Q16539	MAPK14	S226	G230R	230	Missense	distal	4	no	9.180	8.696	EPSD;PhosphoSitePlus	TCGA;ICGC	5.915	Down-regulation
CMGC_MAPK_p38_MAPK14_ST	P04150	NR3C1	Q16539	MAPK14	S226	I219L	219	Missense	distal	-7	no	9.180	9.321	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	5.915	Up-regulation
CMGC_MAPK_p38_MAPK14_ST	P04150	NR3C1	Q16539	MAPK14	S234	A229V	229	Missense	distal	-5	no	6.277	6.769	EPSD	TCGA;ICGC;COSMIC	5.915	Up-regulation
CMGC_MAPK_p38_MAPK14_ST	P04150	NR3C1	Q16539	MAPK14	S234	G230R	230	Missense	distal	-4	no	6.277	6.290	EPSD	TCGA;ICGC	5.915	Up-regulation
CMGC_MAPK_p38_MAPK14_ST	P04150	NR3C1	Q16539	MAPK14	S234	S241L	241	Missense	distal	7	no	6.277	5.892	EPSD	TCGA;ICGC;COSMIC	5.915	Loss
CMGC_MAPK_p38_MAPK14_ST	P04150	NR3C1	Q16539	MAPK14	T288	P289S	289	Missense	proximal	1	no	11.174	3.890	EPSD	TCGA;ICGC;COSMIC	5.915	Loss
CMGC_MAPK_p38_MAPK14_ST	P04150	NR3C1	Q16539	MAPK14	S395	S395I	395	Missense	central	0	yes	9.357	0.000	EPSD	TCGA;ICGC	5.915	Loss
CMGC_MAPK_p38_MAPK14_ST	P04150	NR3C1	Q16539	MAPK14	S404	S404Y	404	Missense	central	0	yes	10.424	0.000	EPSD	TCGA;ICGC	5.915	Loss
CMGC_MAPK_p38_MAPK14_ST	P04150	NR3C1	Q16539	MAPK14	S410	S404Y	404	Missense	distal	-6	no	7.787	7.021	EPSD	TCGA;ICGC	5.915	Down-regulation
CMGC_MAPK_p38_MAPK14_ST	P04150	NR3C1	Q16539	MAPK14	S410	P416Q	416	Missense	distal	6	no	7.787	7.786	EPSD	TCGA;ICGC;COSMIC	5.915	Down-regulation
CMGC_MAPK_p38_MAPK14_ST	P19634	SLC9A1	Q16539	MAPK14	S11	R14W	14	Missense	distal	3	no	9.503	9.587	EPSD	TCGA;COSMIC	5.915	Up-regulation
CMGC_MAPK_p38_MAPK14_ST	P19634	SLC9A1	Q16539	MAPK14	S11	F16I	16	Missense	distal	5	no	9.503	9.851	EPSD	TCGA;ICGC;COSMIC	5.915	Up-regulation
CMGC_MAPK_p38_MAPK14_ST	P19634	SLC9A1	Q16539	MAPK14	T68	T62I	62	Missense	distal	-6	no	12.510	11.488	EPSD	TCGA;ICGC;COSMIC	5.915	Down-regulation
CMGC_MAPK_p38_MAPK14_ST	P19634	SLC9A1	Q16539	MAPK14	T68	N75H	75	Missense	distal	7	no	12.510	12.310	EPSD	TCGA;ICGC;COSMIC	5.915	Down-regulation
CMGC_MAPK_p38_MAPK14_ST	P19634	SLC9A1	Q16539	MAPK14	S693	R698P	698	Missense	distal	5	no	10.047	9.907	EPSD	TCGA;ICGC;COSMIC	5.915	Down-regulation
CMGC_MAPK_p38_MAPK14_ST	P19634	SLC9A1	Q16539	MAPK14	S697	R698P	698	Missense	proximal	1	no	3.908	11.844	EPSD	TCGA;ICGC;COSMIC	5.915	Gain
CMGC_MAPK_p38_MAPK14_ST	P19634	SLC9A1	Q16539	MAPK14	S703	R698P	698	Missense	distal	-5	no	6.509	6.738	EPSD	TCGA;ICGC;COSMIC	5.915	Up-regulation
CMGC_MAPK_p38_MAPK14_ST	P19634	SLC9A1	Q16539	MAPK14	S703	S703L	703	Missense	central	0	yes	6.509	0.000	EPSD	TCGA;ICGC;COSMIC	5.915	Loss
CMGC_MAPK_p38_MAPK14_ST	P19634	SLC9A1	Q16539	MAPK14	S726	D731N	731	Missense	distal	5	no	10.305	10.514	PhosphoSitePlus;EPSD	TCGA;ICGC;COSMIC	5.915	Up-regulation
CMGC_MAPK_p38_MAPK14_ST	P19634	SLC9A1	Q16539	MAPK14	S729	D731N	731	Missense	proximal	2	no	6.960	7.189	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	5.915	Up-regulation
CMGC_MAPK_p38_MAPK14_ST	P19634	SLC9A1	Q16539	MAPK14	S770	R765W	765	Missense	distal	-5	no	5.683	6.429	EPSD	TCGA;ICGC;COSMIC;GDSC	5.915	Gain
CMGC_MAPK_p38_MAPK14_ST	P19634	SLC9A1	Q16539	MAPK14	S771	S770L	770	Missense	proximal	-1	no	6.985	7.263	EPSD	TCGA;COSMIC	5.915	Up-regulation
CMGC_MAPK_p38_MAPK14_ST	P19634	SLC9A1	Q16539	MAPK14	S771	R765W	765	Missense	distal	-6	no	6.985	5.667	EPSD	TCGA;ICGC;COSMIC;GDSC	5.915	Loss
CMGC_MAPK_p38_MAPK14_ST	P19634	SLC9A1	Q16539	MAPK14	T779	A781V	781	Missense	proximal	2	no	11.034	10.870	EPSD	TCGA;COSMIC	5.915	Down-regulation
CMGC_MAPK_p38_MAPK14_ST	P19634	SLC9A1	Q16539	MAPK14	T779	A781T	781	Missense	proximal	2	no	11.034	11.062	EPSD	TCGA;COSMIC	5.915	Up-regulation
CMGC_MAPK_p38_MAPK14_ST	P19634	SLC9A1	Q16539	MAPK14	S785	A781V	781	Missense	distal	-4	no	10.117	10.399	EPSD	TCGA;COSMIC	5.915	Up-regulation
CMGC_MAPK_p38_MAPK14_ST	P19634	SLC9A1	Q16539	MAPK14	S785	A781T	781	Missense	distal	-4	no	10.117	10.354	EPSD	TCGA;COSMIC	5.915	Up-regulation
CMGC_MAPK_p38_MAPK14_ST	P19634	SLC9A1	Q16539	MAPK14	S785	S787I	787	Missense	proximal	2	no	10.117	9.638	EPSD	TCGA;COSMIC	5.915	Down-regulation
CMGC_MAPK_p38_MAPK14_ST	Q09472	EP300	Q16539	MAPK14	S20	K14Q	14	Missense	distal	-6	no	10.459	10.267	EPSD	TCGA;ICGC;COSMIC	5.915	Down-regulation
CMGC_MAPK_p38_MAPK14_ST	Q09472	EP300	Q16539	MAPK14	S20	K17E	17	Missense	distal	-3	no	10.459	10.851	EPSD	TCGA;ICGC;COSMIC	5.915	Up-regulation
CMGC_MAPK_p38_MAPK14_ST	Q09472	EP300	Q16539	MAPK14	S20	A25P	25	Missense	distal	5	no	10.459	10.647	EPSD	TCGA;ICGC;COSMIC	5.915	Up-regulation
CMGC_MAPK_p38_MAPK14_ST	Q09472	EP300	Q16539	MAPK14	S20	P21A	21	Missense	proximal	1	no	10.459	4.140	EPSD	TCGA;ICGC;COSMIC	5.915	Loss
CMGC_MAPK_p38_MAPK14_ST	Q09472	EP300	Q16539	MAPK14	S24	K17E	17	Missense	distal	-7	no	6.820	6.874	EPSD	TCGA;ICGC;COSMIC	5.915	Up-regulation
CMGC_MAPK_p38_MAPK14_ST	Q09472	EP300	Q16539	MAPK14	S24	A25P	25	Missense	proximal	1	no	6.820	13.139	EPSD	TCGA;ICGC;COSMIC	5.915	Up-regulation
CMGC_MAPK_p38_MAPK14_ST	Q09472	EP300	Q16539	MAPK14	S24	P21A	21	Missense	distal	-3	no	6.820	7.172	EPSD	TCGA;ICGC;COSMIC	5.915	Up-regulation
CMGC_MAPK_p38_MAPK14_ST	Q09472	EP300	Q16539	MAPK14	S28	F33V	33	Missense	distal	5	no	5.460	6.245	EPSD	TCGA;ICGC;COSMIC	5.915	Gain
CMGC_MAPK_p38_MAPK14_ST	Q09472	EP300	Q16539	MAPK14	S89	N94S	94	Missense	distal	5	no	8.000	8.336	EPSD	TCGA;ICGC;COSMIC	5.915	Up-regulation
CMGC_MAPK_p38_MAPK14_ST	Q09472	EP300	Q16539	MAPK14	S89	L84S	84	Missense	distal	-5	no	8.000	7.271	EPSD	TCGA;COSMIC	5.915	Down-regulation
CMGC_MAPK_p38_MAPK14_ST	Q09472	EP300	Q16539	MAPK14	S89	R86Q	86	Missense	distal	-3	no	8.000	6.221	EPSD	TCGA;ICGC	5.915	Down-regulation
CMGC_MAPK_p38_MAPK14_ST	Q09472	EP300	Q16539	MAPK14	S90	N94S	94	Missense	distal	4	no	10.176	10.693	EPSD	TCGA;ICGC;COSMIC	5.915	Up-regulation
CMGC_MAPK_p38_MAPK14_ST	Q09472	EP300	Q16539	MAPK14	S90	L84S	84	Missense	distal	-6	no	10.176	11.396	EPSD	TCGA;COSMIC	5.915	Up-regulation
CMGC_MAPK_p38_MAPK14_ST	Q09472	EP300	Q16539	MAPK14	S90	R86Q	86	Missense	distal	-4	no	10.176	10.544	EPSD	TCGA;ICGC	5.915	Up-regulation
CMGC_MAPK_p38_MAPK14_ST	Q09472	EP300	Q16539	MAPK14	S112	N119K	119	Missense	distal	7	no	9.094	8.904	EPSD	TCGA;ICGC;COSMIC	5.915	Down-regulation
CMGC_MAPK_p38_MAPK14_ST	Q09472	EP300	Q16539	MAPK14	S112	G114E	114	Missense	proximal	2	no	9.094	9.288	EPSD	TCGA;ICGC	5.915	Up-regulation
CMGC_MAPK_p38_MAPK14_ST	Q09472	EP300	Q16539	MAPK14	S255	Y257D	257	Missense	proximal	2	no	12.033	11.872	EPSD	TCGA;ICGC;COSMIC	5.915	Down-regulation
CMGC_MAPK_p38_MAPK14_ST	Q09472	EP300	Q16539	MAPK14	S255	N249S	249	Missense	distal	-6	no	12.033	12.456	EPSD	TCGA;ICGC;COSMIC	5.915	Up-regulation
CMGC_MAPK_p38_MAPK14_ST	Q09472	EP300	Q16539	MAPK14	S255	T258I	258	Missense	distal	3	no	12.033	12.115	EPSD	TCGA;ICGC	5.915	Up-regulation
CMGC_MAPK_p38_MAPK14_ST	Q09472	EP300	Q16539	MAPK14	T317	P318A	318	Missense	proximal	1	no	9.145	2.826	EPSD	TCGA;ICGC;COSMIC	5.915	Loss
CMGC_MAPK_p38_MAPK14_ST	Q09472	EP300	Q16539	MAPK14	T317	Q312H	312	Missense	distal	-5	no	9.145	9.731	EPSD	TCGA;ICGC;COSMIC	5.915	Up-regulation
CMGC_MAPK_p38_MAPK14_ST	Q09472	EP300	Q16539	MAPK14	S499	R504L	504	Missense	distal	5	no	10.750	10.113	EPSD	TCGA;ICGC;COSMIC	5.915	Down-regulation
CMGC_MAPK_p38_MAPK14_ST	Q09472	EP300	Q16539	MAPK14	S499	P500L	500	Missense	proximal	1	no	10.750	2.699	EPSD	TCGA;ICGC;COSMIC	5.915	Loss
CMGC_MAPK_p38_MAPK14_ST	Q09472	EP300	Q16539	MAPK14	S831	H828Y	828	Missense	distal	-3	no	9.403	9.750	EPSD	TCGA;ICGC;COSMIC	5.915	Up-regulation
CMGC_MAPK_p38_MAPK14_ST	Q09472	EP300	Q16539	MAPK14	S831	S833L	833	Missense	proximal	2	no	9.403	8.914	EPSD	TCGA;ICGC;COSMIC	5.915	Down-regulation
CMGC_MAPK_p38_MAPK14_ST	Q09472	EP300	Q16539	MAPK14	S833	H828Y	828	Missense	distal	-5	no	12.412	12.099	EPSD	TCGA;ICGC;COSMIC	5.915	Down-regulation
CMGC_MAPK_p38_MAPK14_ST	Q09472	EP300	Q16539	MAPK14	S833	S833L	833	Missense	central	0	yes	12.412	0.000	EPSD	TCGA;ICGC;COSMIC	5.915	Loss
CMGC_MAPK_p38_MAPK14_ST	Q09472	EP300	Q16539	MAPK14	T839	S833L	833	Missense	distal	-6	no	9.838	8.618	EPSD	TCGA;ICGC;COSMIC	5.915	Down-regulation
CMGC_MAPK_p38_MAPK14_ST	Q09472	EP300	Q16539	MAPK14	T865	P867S	867	Missense	proximal	2	no	10.860	11.237	EPSD	TCGA;ICGC;COSMIC	5.915	Up-regulation
CMGC_MAPK_p38_MAPK14_ST	Q09472	EP300	Q16539	MAPK14	T938	P933L	933	Missense	distal	-5	no	7.571	7.853	EPSD	TCGA;ICGC;COSMIC	5.915	Up-regulation
CMGC_MAPK_p38_MAPK14_ST	Q09472	EP300	Q16539	MAPK14	S1033	P1039L	1039	Missense	distal	6	no	7.714	7.575	EPSD	TCGA;ICGC;COSMIC	5.915	Down-regulation
CMGC_MAPK_p38_MAPK14_ST	Q09472	EP300	Q16539	MAPK14	S1038	P1039L	1039	Missense	proximal	1	no	10.963	2.912	EPSD	TCGA;ICGC;COSMIC	5.915	Loss
CMGC_MAPK_p38_MAPK14_ST	Q09472	EP300	Q16539	MAPK14	S1038	K1045N	1045	Missense	distal	7	no	10.963	11.153	EPSD	TCGA;ICGC;COSMIC;CCLE	5.915	Up-regulation
CMGC_MAPK_p38_MAPK14_ST	Q09472	EP300	Q16539	MAPK14	S1193	D1188H	1188	Missense	distal	-5	no	6.121	6.260	EPSD	TCGA;ICGC;COSMIC	5.915	Up-regulation
CMGC_MAPK_p38_MAPK14_ST	Q09472	EP300	Q16539	MAPK14	S1193	F1200L	1200	Missense	distal	7	no	6.121	6.607	EPSD	TCGA;ICGC;COSMIC	5.915	Up-regulation
CMGC_MAPK_p38_MAPK14_ST	Q09472	EP300	Q16539	MAPK14	S1193	Y1198F	1198	Missense	distal	5	no	6.121	4.959	EPSD	TCGA;ICGC;COSMIC	5.915	Loss
CMGC_MAPK_p38_MAPK14_ST	Q09472	EP300	Q16539	MAPK14	S1193	A1189V	1189	Missense	distal	-4	no	6.121	6.404	EPSD	TCGA;ICGC;COSMIC	5.915	Up-regulation
CMGC_MAPK_p38_MAPK14_ST	Q09472	EP300	Q16539	MAPK14	S1193	H1199Y	1199	Missense	distal	6	no	6.121	6.247	EPSD	TCGA;ICGC;COSMIC	5.915	Up-regulation
CMGC_MAPK_p38_MAPK14_ST	Q09472	EP300	Q16539	MAPK14	S1849	Q1843P	1843	Missense	distal	-6	no	9.238	9.408	EPSD	TCGA;ICGC;COSMIC	5.915	Up-regulation
CMGC_MAPK_p38_MAPK14_ST	Q09472	EP300	Q16539	MAPK14	T1857	T1864S	1864	Missense	distal	7	no	10.922	11.243	EPSD	TCGA;ICGC;COSMIC	5.915	Up-regulation
CMGC_MAPK_p38_MAPK14_ST	Q09472	EP300	Q16539	MAPK14	T1865	T1864S	1864	Missense	proximal	-1	no	8.723	8.607	EPSD	TCGA;ICGC;COSMIC	5.915	Down-regulation
CMGC_MAPK_p38_MAPK14_ST	Q09472	EP300	Q16539	MAPK14	T1906	Q1904P	1904	Missense	proximal	-2	no	9.300	10.315	EPSD	TCGA;ICGC;COSMIC	5.915	Up-regulation
CMGC_MAPK_p38_MAPK14_ST	Q09472	EP300	Q16539	MAPK14	T1906	A1901V	1901	Missense	distal	-5	no	9.300	9.791	EPSD	TCGA;ICGC;COSMIC	5.915	Up-regulation
CMGC_MAPK_p38_MAPK14_ST	Q09472	EP300	Q16539	MAPK14	T1909	Q1904P	1904	Missense	distal	-5	no	11.278	11.550	EPSD	TCGA;ICGC;COSMIC	5.915	Up-regulation
CMGC_MAPK_p38_MAPK14_ST	Q09472	EP300	Q16539	MAPK14	T1960	P1958L	1958	Missense	proximal	-2	no	7.424	6.044	EPSD	TCGA;ICGC;COSMIC	5.915	Down-regulation
CMGC_MAPK_p38_MAPK14_ST	Q09472	EP300	Q16539	MAPK14	T1960	M1962T	1962	Missense	proximal	2	no	7.424	7.442	EPSD	TCGA	5.915	Up-regulation
CMGC_MAPK_p38_MAPK14_ST	Q09472	EP300	Q16539	MAPK14	S2279	M2284V	2284	Missense	distal	5	no	10.469	10.291	EPSD	TCGA;ICGC;COSMIC	5.915	Down-regulation
CMGC_MAPK_p38_MAPK14_ST	Q09472	EP300	Q16539	MAPK14	S2309	R2308C	2308	Missense	proximal	-1	no	7.151	7.414	EPSD	TCGA;ICGC;COSMIC	5.915	Up-regulation
CMGC_MAPK_p38_MAPK14_ST	Q09472	EP300	Q16539	MAPK14	S2315	R2308C	2308	Missense	distal	-7	no	13.154	12.762	EPSD	TCGA;ICGC;COSMIC	5.915	Down-regulation
CMGC_MAPK_p38_MAPK14_ST	Q09472	EP300	Q16539	MAPK14	S2315	R2317Q	2317	Missense	proximal	2	no	13.154	12.727	EPSD	TCGA;ICGC;COSMIC	5.915	Down-regulation
CMGC_MAPK_p38_MAPK14_ST	Q09472	EP300	Q16539	MAPK14	S2315	R2317L	2317	Missense	proximal	2	no	13.154	12.810	EPSD	TCGA;ICGC;COSMIC	5.915	Down-regulation
CMGC_MAPK_p38_MAPK14_ST	Q09472	EP300	Q16539	MAPK14	S2326	P2327H	2327	Missense	proximal	1	no	8.849	-4.805	EPSD	TCGA;ICGC	5.915	Loss
CMGC_MAPK_p38_MAPK14_ST	Q09472	EP300	Q16539	MAPK14	S2328	P2327H	2327	Missense	proximal	-1	no	13.309	13.264	EPSD	TCGA;ICGC	5.915	Down-regulation
CMGC_MAPK_p38_MAPK14_ST	Q09472	EP300	Q16539	MAPK14	S2366	E2360G	2360	Missense	distal	-6	no	11.588	11.278	EPSD	TCGA;ICGC;COSMIC	5.915	Down-regulation
CMGC_MAPK_p38_MAPK14_ST	Q09472	EP300	Q16539	MAPK14	S2366	S2366N	2366	Missense	central	0	yes	11.588	0.000	EPSD	TCGA;ICGC;COSMIC	5.915	Loss
CMGC_MAPK_p38_MAPK14_ST	Q09472	EP300	Q16539	MAPK14	S2366	D2368N	2368	Missense	proximal	2	no	11.588	11.818	EPSD	TCGA;ICGC;COSMIC	5.915	Up-regulation
CMGC_MAPK_p38_MAPK14_ST	Q09472	EP300	Q16539	MAPK14	S2366	L2373I	2373	Missense	distal	7	no	11.588	11.240	EPSD	TCGA;ICGC	5.915	Down-regulation
CMGC_MAPK_p38_MAPK14_ST	P15336	ATF2	Q16539	MAPK14	T69	P70S	70	Missense	proximal	1	no	11.101	3.817	PhosphoSitePlus;EPSD	TCGA;COSMIC	5.915	Loss
CMGC_MAPK_p38_MAPK14_ST	P15336	ATF2	Q16539	MAPK14	T71	P70S	70	Missense	proximal	-1	no	9.601	9.508	EPSD;PhosphoSitePlus	TCGA;COSMIC	5.915	Down-regulation
CMGC_MAPK_p38_MAPK14_ST	P15336	ATF2	Q16539	MAPK14	S90	E93Q	93	Missense	distal	3	no	10.813	10.886	EPSD	TCGA;COSMIC	5.915	Up-regulation
CMGC_MAPK_p38_MAPK14_ST	P15336	ATF2	Q16539	MAPK14	S90	G83D	83	Missense	distal	-7	no	10.813	10.450	EPSD	TCGA;COSMIC	5.915	Down-regulation
CMGC_MAPK_p38_MAPK14_ST	P15336	ATF2	Q16539	MAPK14	S112	T116A	116	Missense	distal	4	no	6.930	6.885	EPSD	TCGA;COSMIC	5.915	Down-regulation
CMGC_MAPK_p38_MAPK14_ST	P15336	ATF2	Q16539	MAPK14	S112	S112P	112	Missense	central	0	yes	6.930	0.000	EPSD	TCGA;COSMIC	5.915	Loss
CMGC_MAPK_p38_MAPK14_ST	P15336	ATF2	Q16539	MAPK14	T116	T116A	116	Missense	central	0	yes	6.954	0.000	EPSD	TCGA;COSMIC	5.915	Loss
CMGC_MAPK_p38_MAPK14_ST	P15336	ATF2	Q16539	MAPK14	T116	S112P	112	Missense	distal	-4	no	6.954	7.042	EPSD	TCGA;COSMIC	5.915	Up-regulation
CMGC_MAPK_p38_MAPK14_ST	P15336	ATF2	Q16539	MAPK14	S136	D135N	135	Missense	proximal	-1	no	8.563	8.378	EPSD	TCGA	5.915	Down-regulation
CMGC_MAPK_p38_MAPK14_ST	P15336	ATF2	Q16539	MAPK14	S136	S136N	136	Missense	central	0	yes	8.563	0.000	EPSD	TCGA	5.915	Loss
CMGC_MAPK_p38_MAPK14_ST	P15336	ATF2	Q16539	MAPK14	S266	G260E	260	Missense	distal	-6	no	10.420	10.730	EPSD	TCGA;COSMIC	5.915	Up-regulation
CMGC_MAPK_p38_MAPK14_ST	P15336	ATF2	Q16539	MAPK14	S266	P267S	267	Missense	proximal	1	no	10.420	3.136	EPSD	TCGA;COSMIC	5.915	Loss
CMGC_MAPK_p38_MAPK14_ST	P15336	ATF2	Q16539	MAPK14	S266	G263C	263	Missense	distal	-3	no	10.420	9.674	EPSD	TCGA;COSMIC	5.915	Down-regulation
CMGC_MAPK_p38_MAPK14_ST	P15336	ATF2	Q16539	MAPK14	S307	P312L	312	Missense	distal	5	no	8.199	7.702	EPSD	TCGA;COSMIC	5.915	Down-regulation
CMGC_MAPK_p38_MAPK14_ST	P15336	ATF2	Q16539	MAPK14	S307	E308Q	308	Missense	proximal	1	no	8.199	8.750	EPSD	TCGA;COSMIC	5.915	Up-regulation
CMGC_MAPK_p38_MAPK14_ST	P15336	ATF2	Q16539	MAPK14	S307	R304S	304	Missense	distal	-3	no	8.199	7.686	EPSD	TCGA;COSMIC	5.915	Down-regulation
CMGC_MAPK_p38_MAPK14_ST	P15336	ATF2	Q16539	MAPK14	S307	S310F	310	Missense	distal	3	no	8.199	8.307	EPSD	TCGA;COSMIC	5.915	Up-regulation
CMGC_MAPK_p38_MAPK14_ST	P15336	ATF2	Q16539	MAPK14	T320	P326S	326	Missense	distal	6	no	7.720	7.708	EPSD	TCGA;COSMIC	5.915	Down-regulation
CMGC_MAPK_p38_MAPK14_ST	P15336	ATF2	Q16539	MAPK14	T320	S321F	321	Missense	proximal	1	no	7.720	9.000	EPSD	TCGA;COSMIC	5.915	Up-regulation
CMGC_MAPK_p38_MAPK14_ST	P15336	ATF2	Q16539	MAPK14	T325	P326S	326	Missense	proximal	1	no	9.210	1.926	EPSD	TCGA;COSMIC	5.915	Loss
CMGC_MAPK_p38_MAPK14_ST	P15336	ATF2	Q16539	MAPK14	T325	S321F	321	Missense	distal	-4	no	9.210	9.914	EPSD	TCGA;COSMIC	5.915	Up-regulation
CMGC_MAPK_p38_MAPK14_ST	P15336	ATF2	Q16539	MAPK14	S328	P326S	326	Missense	proximal	-2	no	11.961	11.473	EPSD	TCGA;COSMIC	5.915	Down-regulation
CMGC_MAPK_p38_MAPK14_ST	P15336	ATF2	Q16539	MAPK14	S328	P334A	334	Missense	distal	6	no	11.961	12.004	EPSD	TCGA;COSMIC	5.915	Up-regulation
CMGC_MAPK_p38_MAPK14_ST	P15336	ATF2	Q16539	MAPK14	S328	S321F	321	Missense	distal	-7	no	11.961	11.215	EPSD	TCGA;COSMIC	5.915	Down-regulation
CMGC_MAPK_p38_MAPK14_ST	P15336	ATF2	Q16539	MAPK14	T333	P326S	326	Missense	distal	-7	no	10.979	11.066	EPSD	TCGA;COSMIC	5.915	Up-regulation
CMGC_MAPK_p38_MAPK14_ST	P15336	ATF2	Q16539	MAPK14	T333	P334A	334	Missense	proximal	1	no	10.979	4.661	EPSD	TCGA;COSMIC	5.915	Loss
CMGC_MAPK_p38_MAPK14_ST	P15336	ATF2	Q16539	MAPK14	T333	T339A	339	Missense	distal	6	no	10.979	10.997	EPSD	TCGA;COSMIC	5.915	Up-regulation
CMGC_MAPK_p38_MAPK14_ST	P15336	ATF2	Q16539	MAPK14	T336	P334A	334	Missense	proximal	-2	no	6.363	5.701	EPSD	TCGA;COSMIC	5.915	Loss
CMGC_MAPK_p38_MAPK14_ST	P15336	ATF2	Q16539	MAPK14	T336	T339A	339	Missense	distal	3	no	6.363	6.364	EPSD	TCGA;COSMIC	5.915	Up-regulation
CMGC_MAPK_p38_MAPK14_ST	P15336	ATF2	Q16539	MAPK14	S446	Q453H	453	Missense	distal	7	no	9.742	9.402	EPSD	TCGA;COSMIC	5.915	Down-regulation
CMGC_MAPK_p38_MAPK14_ST	P15336	ATF2	Q16539	MAPK14	S498	S500L	500	Missense	proximal	2	no	6.203	5.714	EPSD	TCGA;COSMIC	5.915	Loss
CMGC_MAPK_p38_MAPK14_ST	P15336	ATF2	Q16539	MAPK14	S498	Q499L	499	Missense	proximal	1	no	6.203	5.361	EPSD	TCGA;COSMIC	5.915	Loss
CMGC_MAPK_p38_MAPK14_ST	P15336	ATF2	Q16539	MAPK14	S498	P502L	502	Missense	distal	4	no	6.203	5.564	EPSD	TCGA;COSMIC	5.915	Loss
CMGC_MAPK_p38_MAPK14_ST	P15336	ATF2	Q16539	MAPK14	S498	P502T	502	Missense	distal	4	no	6.203	6.381	EPSD	TCGA;COSMIC	5.915	Up-regulation
CMGC_MAPK_p38_MAPK14_ST	Q9NRR4	DROSHA	Q16539	MAPK14	S201	N198T	198	Missense	distal	-3	no	9.068	9.898	EPSD	TCGA;ICGC;COSMIC	5.915	Up-regulation
CMGC_MAPK_p38_MAPK14_ST	Q9NRR4	DROSHA	Q16539	MAPK14	S221	P222L	222	Missense	proximal	1	no	11.714	3.663	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	5.915	Loss
CMGC_MAPK_p38_MAPK14_ST	Q9NRR4	DROSHA	Q16539	MAPK14	S221	P222A	222	Missense	proximal	1	no	11.714	5.396	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	5.915	Loss
CMGC_MAPK_p38_MAPK14_ST	Q9NRR4	DROSHA	Q16539	MAPK14	T274	R273I	273	Missense	proximal	-1	no	11.616	11.702	EPSD;PhosphoSitePlus	TCGA	5.915	Up-regulation
CMGC_MAPK_p38_MAPK14_ST	Q9NRR4	DROSHA	Q16539	MAPK14	T274	D270Y	270	Missense	distal	-4	no	11.616	11.119	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	5.915	Down-regulation
CMGC_MAPK_p38_MAPK14_ST	Q9NRR4	DROSHA	Q16539	MAPK14	T274	D268V	268	Missense	distal	-6	no	11.616	11.334	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	5.915	Down-regulation
CMGC_MAPK_p38_MAPK14_ST	Q9NRR4	DROSHA	Q16539	MAPK14	T274	S280C	280	Missense	distal	6	no	11.616	11.341	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	5.915	Down-regulation
CMGC_MAPK_p38_MAPK14_ST	Q9NRR4	DROSHA	Q16539	MAPK14	S300	R305T	305	Missense	distal	5	no	12.619	12.763	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	5.915	Up-regulation
CMGC_MAPK_p38_MAPK14_ST	Q9NRR4	DROSHA	Q16539	MAPK14	S300	E304A	304	Missense	distal	4	no	12.619	11.814	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	5.915	Down-regulation
CMGC_MAPK_p38_MAPK14_ST	Q9NRR4	DROSHA	Q16539	MAPK14	T330	G335E	335	Missense	distal	5	no	11.414	11.632	EPSD	TCGA;ICGC	5.915	Up-regulation
CMGC_MAPK_p38_MAPK14_ST	Q9NRR4	DROSHA	Q16539	MAPK14	S355	R354C	354	Missense	proximal	-1	no	9.148	9.411	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	5.915	Up-regulation
CMGC_MAPK_p38_MAPK14_ST	Q9NRR4	DROSHA	Q16539	MAPK14	S807	R801C	801	Missense	distal	-6	no	12.762	11.575	EPSD	TCGA;COSMIC	5.915	Down-regulation
CMGC_MAPK_p38_MAPK14_ST	Q9NRR4	DROSHA	Q16539	MAPK14	S807	L800R	800	Missense	distal	-7	no	12.762	12.873	EPSD	TCGA	5.915	Up-regulation
CMGC_MAPK_p38_MAPK14_ST	Q9NRR4	DROSHA	Q16539	MAPK14	T958	S960W	960	Missense	proximal	2	no	6.717	6.073	EPSD	TCGA;ICGC;COSMIC	5.915	Down-regulation
CMGC_MAPK_p38_MAPK14_ST	Q9NRR4	DROSHA	Q16539	MAPK14	T958	N963S	963	Missense	distal	5	no	6.717	7.052	EPSD	TCGA;COSMIC	5.915	Up-regulation
CMGC_MAPK_p38_MAPK14_ST	Q9NRR4	DROSHA	Q16539	MAPK14	T958	S960L	960	Missense	proximal	2	no	6.717	6.227	EPSD	TCGA;ICGC;COSMIC;GDSC;CCLE	5.915	Down-regulation
CMGC_MAPK_p38_MAPK14_ST	Q9NRR4	DROSHA	Q16539	MAPK14	T958	D955Y	955	Missense	distal	-3	no	6.717	6.811	EPSD	TCGA;ICGC;COSMIC	5.915	Up-regulation
CMGC_MAPK_p38_MAPK14_ST	P42224	STAT1	Q16539	MAPK14	T489	R494Q	494	Missense	distal	5	no	8.681	8.332	EPSD	TCGA;ICGC;COSMIC	5.915	Down-regulation
CMGC_MAPK_p38_MAPK14_ST	P42224	STAT1	Q16539	MAPK14	S532	P538L	538	Missense	distal	6	no	6.527	6.388	EPSD	TCGA;ICGC;COSMIC	5.915	Down-regulation
CMGC_MAPK_p38_MAPK14_ST	P42224	STAT1	Q16539	MAPK14	S532	D534N	534	Missense	proximal	2	no	6.527	6.757	EPSD	TCGA;ICGC;COSMIC	5.915	Up-regulation
CMGC_MAPK_p38_MAPK14_ST	P42224	STAT1	Q16539	MAPK14	S532	P538S	538	Missense	distal	6	no	6.527	6.515	EPSD	TCGA;ICGC;COSMIC	5.915	Down-regulation
CMGC_MAPK_p38_MAPK14_ST	P42224	STAT1	Q16539	MAPK14	S532	A531T	531	Missense	proximal	-1	no	6.527	6.584	EPSD	TCGA;ICGC;COSMIC	5.915	Up-regulation
CMGC_MAPK_p38_MAPK14_ST	P42224	STAT1	Q16539	MAPK14	S727	D732H	732	Missense	distal	5	no	12.060	11.600	PhosphoSitePlus	TCGA;ICGC;COSMIC	5.915	Down-regulation
CMGC_MAPK_p38_MAPK14_ST	P42224	STAT1	Q16539	MAPK14	S727	E733K	733	Missense	distal	6	no	12.060	12.055	PhosphoSitePlus	TCGA;ICGC;COSMIC	5.915	Down-regulation
CMGC_MAPK_p38_MAPK14_ST	Q99958	FOXC2	Q16539	MAPK14	S36	V40I	40	Missense	distal	4	no	9.686	9.637	EPSD	TCGA;ICGC;COSMIC	5.915	Down-regulation
CMGC_MAPK_p38_MAPK14_ST	Q99958	FOXC2	Q16539	MAPK14	S36	Y41H	41	Missense	distal	5	no	9.686	8.961	EPSD	TCGA;ICGC;COSMIC	5.915	Down-regulation
CMGC_MAPK_p38_MAPK14_ST	Q99958	FOXC2	Q16539	MAPK14	T197	A190V	190	Missense	distal	-7	no	13.330	12.512	EPSD	TCGA;ICGC;COSMIC;GDSC	5.915	Down-regulation
CMGC_MAPK_p38_MAPK14_ST	Q99958	FOXC2	Q16539	MAPK14	T197	A194D	194	Missense	distal	-3	no	13.330	12.753	EPSD	TCGA;ICGC	5.915	Down-regulation
CMGC_MAPK_p38_MAPK14_ST	Q99958	FOXC2	Q16539	MAPK14	S219	E216K	216	Missense	distal	-3	no	8.063	7.670	EPSD	TCGA;ICGC;COSMIC;CCLE	5.915	Down-regulation
CMGC_MAPK_p38_MAPK14_ST	Q99958	FOXC2	Q16539	MAPK14	S219	A221V	221	Missense	proximal	2	no	8.063	7.899	EPSD	TCGA;ICGC;COSMIC	5.915	Down-regulation
CMGC_MAPK_p38_MAPK14_ST	Q99958	FOXC2	Q16539	MAPK14	T484	P485Q	485	Missense	proximal	1	no	10.131	2.923	EPSD	TCGA;ICGC;COSMIC	5.915	Loss
CMGC_MAPK_p38_MAPK14_ST	Q99958	FOXC2	Q16539	MAPK14	T484	R489L	489	Missense	distal	5	no	10.131	9.494	EPSD	TCGA;ICGC;COSMIC	5.915	Down-regulation
CMGC_MAPK_p38_MAPK14_ST	Q99958	FOXC2	Q16539	MAPK14	T484	R489C	489	Missense	distal	5	no	10.131	9.261	EPSD	TCGA;ICGC;COSMIC	5.915	Down-regulation
CMGC_MAPK_p38_MAPK14_ST	P36956	SREBF1	Q16539	MAPK14	T105	P106A	106	Missense	proximal	1	no	9.499	3.181	EPSD	TCGA;COSMIC	5.915	Loss
CMGC_MAPK_p38_MAPK14_ST	P36956	SREBF1	Q16539	MAPK14	T105	S98P	98	Missense	distal	-7	no	9.499	9.412	EPSD	TCGA;COSMIC	5.915	Down-regulation
CMGC_MAPK_p38_MAPK14_ST	P36956	SREBF1	Q16539	MAPK14	S117	F116S	116	Missense	proximal	-1	no	9.578	9.335	EPSD	TCGA;COSMIC	5.915	Down-regulation
CMGC_MAPK_p38_MAPK14_ST	P36956	SREBF1	Q16539	MAPK14	T426	T419I	419	Missense	distal	-7	no	11.359	11.007	EPSD;PhosphoSitePlus	TCGA;COSMIC	5.915	Down-regulation
CMGC_MAPK_p38_MAPK14_ST	P36956	SREBF1	Q16539	MAPK14	T426	V421A	421	Missense	distal	-5	no	11.359	10.867	EPSD;PhosphoSitePlus	TCGA	5.915	Down-regulation
CMGC_MAPK_p38_MAPK14_ST	P36956	SREBF1	Q16539	MAPK14	S461	P459L	459	Missense	proximal	-2	no	11.989	10.609	EPSD	TCGA	5.915	Down-regulation
CMGC_MAPK_p38_MAPK14_ST	P38936	CDKN1A	Q16539	MAPK14	T57	G61V	61	Missense	distal	4	no	8.710	8.202	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	5.915	Down-regulation
CMGC_MAPK_p38_MAPK14_ST	P38936	CDKN1A	Q16539	MAPK14	T57	E56K	56	Missense	proximal	-1	no	8.710	8.771	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	5.915	Up-regulation
CMGC_MAPK_p38_MAPK14_ST	P38936	CDKN1A	Q16539	MAPK14	T57	P58L	58	Missense	proximal	1	no	8.710	0.659	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	5.915	Loss
CMGC_MAPK_p38_MAPK14_ST	P38936	CDKN1A	Q16539	MAPK14	S98	R94W	94	Missense	distal	-4	no	8.521	9.151	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	5.915	Up-regulation
CMGC_MAPK_p38_MAPK14_ST	P38936	CDKN1A	Q16539	MAPK14	S98	R93S	93	Missense	distal	-5	no	8.521	8.303	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	5.915	Down-regulation
CMGC_MAPK_p38_MAPK14_ST	P38936	CDKN1A	Q16539	MAPK14	S98	R94P	94	Missense	distal	-4	no	8.521	8.598	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	5.915	Up-regulation
CMGC_MAPK_p38_MAPK14_ST	P38936	CDKN1A	Q16539	MAPK14	S98	P95S	95	Missense	distal	-3	no	8.521	9.285	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	5.915	Up-regulation
CMGC_MAPK_p38_MAPK14_ST	P38936	CDKN1A	Q16539	MAPK14	S130	D136H	136	Missense	distal	6	no	13.304	13.217	PhosphoSitePlus;EPSD	TCGA;ICGC;COSMIC	5.915	Down-regulation
CMGC_MAPK_p38_MAPK14_ST	P38936	CDKN1A	Q16539	MAPK14	S130	G132C	132	Missense	proximal	2	no	13.304	13.120	PhosphoSitePlus;EPSD	TCGA;ICGC;COSMIC	5.915	Down-regulation
CMGC_MAPK_p38_MAPK14_ST	P38936	CDKN1A	Q16539	MAPK14	S130	E128K	128	Missense	proximal	-2	no	13.304	12.274	PhosphoSitePlus;EPSD	TCGA;ICGC;COSMIC	5.915	Down-regulation
CMGC_MAPK_p38_MAPK14_ST	P38936	CDKN1A	Q16539	MAPK14	S130	G135A	135	Missense	distal	5	no	13.304	12.921	PhosphoSitePlus;EPSD	TCGA	5.915	Down-regulation
CMGC_MAPK_p38_MAPK14_ST	P38936	CDKN1A	Q16539	MAPK14	S146	R142W	142	Missense	distal	-4	no	5.717	6.346	EPSD	TCGA;ICGC;COSMIC;GDSC;CCLE	5.915	Gain
CMGC_MAPK_p38_MAPK14_ST	Q15750	TAB1	Q16539	MAPK14	S339	R336C	336	Missense	distal	-3	no	6.260	4.064	EPSD	TCGA;ICGC;COSMIC	5.915	Loss
CMGC_MAPK_p38_MAPK14_ST	Q15750	TAB1	Q16539	MAPK14	S339	R336H	336	Missense	distal	-3	no	6.260	4.506	EPSD	TCGA;ICGC;COSMIC	5.915	Loss
CMGC_MAPK_p38_MAPK14_ST	Q15750	TAB1	Q16539	MAPK14	S339	R333P	333	Missense	distal	-6	no	6.260	5.759	EPSD	TCGA;ICGC;COSMIC	5.915	Loss
CMGC_MAPK_p38_MAPK14_ST	Q15750	TAB1	Q16539	MAPK14	S339	D340N	340	Missense	proximal	1	no	6.260	5.888	EPSD	TCGA;ICGC;COSMIC	5.915	Loss
CMGC_MAPK_p38_MAPK14_ST	Q15750	TAB1	Q16539	MAPK14	S423	G420R	420	Missense	distal	-3	no	5.405	6.855	PhosphoSitePlus;EPSD	TCGA;ICGC	5.915	Gain
CMGC_MAPK_p38_MAPK14_ST	Q15750	TAB1	Q16539	MAPK14	T431	E429K	429	Missense	proximal	-2	no	10.605	9.574	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	5.915	Down-regulation
CMGC_MAPK_p38_MAPK14_ST	Q15750	TAB1	Q16539	MAPK14	T431	A430T	430	Missense	proximal	-1	no	10.605	10.661	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	5.915	Up-regulation
CMGC_MAPK_p38_MAPK14_ST	Q15750	TAB1	Q16539	MAPK14	T431	T433I	433	Missense	proximal	2	no	10.605	10.361	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	5.915	Down-regulation
CMGC_MAPK_p38_MAPK14_ST	Q15750	TAB1	Q16539	MAPK14	S438	T433I	433	Missense	distal	-5	no	11.609	11.568	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	5.915	Down-regulation
CMGC_MAPK_p38_MAPK14_ST	Q15750	TAB1	Q16539	MAPK14	S453	D458N	458	Missense	distal	5	no	6.000	6.209	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	5.915	Up-regulation
CMGC_MAPK_p38_MAPK14_ST	Q15750	TAB1	Q16539	MAPK14	S492	V493M	493	Missense	proximal	1	no	5.782	7.897	EPSD	TCGA;ICGC;COSMIC	5.915	Gain
CMGC_MAPK_p38_MAPK14_ST	Q15750	TAB1	Q16539	MAPK14	S492	L490P	490	Missense	proximal	-2	no	5.782	7.162	EPSD	TCGA;ICGC;COSMIC	5.915	Gain
CMGC_MAPK_p38_MAPK14_ST	Q8WYK2	JDP2	Q16539	MAPK14	T143	R136L	136	Missense	distal	-7	no	6.578	6.467	EPSD	TCGA;ICGC;COSMIC	5.915	Down-regulation
CMGC_MAPK_p38_MAPK14_ST	P78356	PIP4K2B	Q16539	MAPK14	T9	A14V	14	Missense	distal	5	no	6.080	6.061	EPSD	TCGA;ICGC	5.915	Down-regulation
CMGC_MAPK_p38_MAPK14_ST	P78356	PIP4K2B	Q16539	MAPK14	T9	L16P	16	Missense	distal	7	no	6.080	6.243	EPSD	TCGA;ICGC	5.915	Up-regulation
CMGC_MAPK_p38_MAPK14_ST	P78356	PIP4K2B	Q16539	MAPK14	S17	A14V	14	Missense	distal	-3	no	5.926	4.425	EPSD	TCGA;ICGC	5.915	Loss
CMGC_MAPK_p38_MAPK14_ST	P78356	PIP4K2B	Q16539	MAPK14	S17	T23I	23	Missense	distal	6	no	5.926	5.677	EPSD	TCGA;ICGC	5.915	Loss
CMGC_MAPK_p38_MAPK14_ST	P78356	PIP4K2B	Q16539	MAPK14	S17	L16P	16	Missense	proximal	-1	no	5.926	5.740	EPSD	TCGA;ICGC	5.915	Loss
CMGC_MAPK_p38_MAPK14_ST	P78356	PIP4K2B	Q16539	MAPK14	S17	K24N	24	Missense	distal	7	no	5.926	6.116	EPSD	TCGA;ICGC	5.915	Up-regulation
CMGC_MAPK_p38_MAPK14_ST	P78356	PIP4K2B	Q16539	MAPK14	T322	Y320F	320	Missense	proximal	-2	no	10.505	9.778	EPSD	TCGA;ICGC	5.915	Down-regulation
CMGC_MAPK_p38_MAPK14_ST	P78356	PIP4K2B	Q16539	MAPK14	T322	P323L	323	Missense	proximal	1	no	10.505	2.454	EPSD	TCGA;ICGC	5.915	Loss
CMGC_MAPK_p38_MAPK14_ST	P78356	PIP4K2B	Q16539	MAPK14	T322	P323S	323	Missense	proximal	1	no	10.505	3.221	EPSD	TCGA;ICGC	5.915	Loss
CMGC_MAPK_p38_MAPK14_ST	P78356	PIP4K2B	Q16539	MAPK14	S326	Y320F	320	Missense	distal	-6	no	10.073	9.074	PhosphoSitePlus	TCGA;ICGC	5.915	Down-regulation
CMGC_MAPK_p38_MAPK14_ST	P78356	PIP4K2B	Q16539	MAPK14	S326	P323L	323	Missense	distal	-3	no	10.073	9.105	PhosphoSitePlus	TCGA;ICGC	5.915	Down-regulation
CMGC_MAPK_p38_MAPK14_ST	P78356	PIP4K2B	Q16539	MAPK14	S326	P323S	323	Missense	distal	-3	no	10.073	10.836	PhosphoSitePlus	TCGA;ICGC	5.915	Up-regulation
CMGC_MAPK_p38_MAPK14_ST	P78536	ADAM17	Q16539	MAPK14	S180	P181L	181	Missense	proximal	1	no	12.921	4.871	EPSD	TCGA;ICGC;COSMIC	5.915	Loss
CMGC_MAPK_p38_MAPK14_ST	P78536	ADAM17	Q16539	MAPK14	S180	S176L	176	Missense	distal	-4	no	12.921	13.521	EPSD	TCGA;ICGC;COSMIC	5.915	Up-regulation
CMGC_MAPK_p38_MAPK14_ST	P78536	ADAM17	Q16539	MAPK14	S180	R177C	177	Missense	distal	-3	no	12.921	10.726	EPSD	TCGA;ICGC;COSMIC	5.915	Down-regulation
CMGC_MAPK_p38_MAPK14_ST	P78536	ADAM17	Q16539	MAPK14	S266	R263Q	263	Missense	distal	-3	no	7.242	5.463	EPSD	TCGA;COSMIC	5.915	Loss
CMGC_MAPK_p38_MAPK14_ST	Q14721	KCNB1	Q16539	MAPK14	S496	W490L	490	Missense	distal	-6	no	6.348	6.552	EPSD	TCGA;ICGC;COSMIC	5.915	Up-regulation
CMGC_MAPK_p38_MAPK14_ST	Q14721	KCNB1	Q16539	MAPK14	S496	S503F	503	Missense	distal	7	no	6.348	5.478	EPSD	TCGA;ICGC;COSMIC	5.915	Loss
CMGC_MAPK_p38_MAPK14_ST	Q14721	KCNB1	Q16539	MAPK14	S496	T491A	491	Missense	distal	-5	no	6.348	6.019	EPSD	TCGA;ICGC	5.915	Down-regulation
CMGC_MAPK_p38_MAPK14_ST	Q14721	KCNB1	Q16539	MAPK14	S503	E508K	508	Missense	distal	5	no	7.680	7.113	EPSD	TCGA;ICGC;COSMIC	5.915	Down-regulation
CMGC_MAPK_p38_MAPK14_ST	Q14721	KCNB1	Q16539	MAPK14	S503	S503F	503	Missense	central	0	yes	7.680	0.000	EPSD	TCGA;ICGC;COSMIC	5.915	Loss
CMGC_MAPK_p38_MAPK14_ST	Q14721	KCNB1	Q16539	MAPK14	S520	P521H	521	Missense	proximal	1	no	9.837	-3.817	EPSD	TCGA;ICGC;COSMIC	5.915	Loss
CMGC_MAPK_p38_MAPK14_ST	Q14721	KCNB1	Q16539	MAPK14	S520	S519C	519	Missense	proximal	-1	no	9.837	9.992	EPSD	TCGA;ICGC;COSMIC	5.915	Up-regulation
CMGC_MAPK_p38_MAPK14_ST	Q14721	KCNB1	Q16539	MAPK14	S520	S519F	519	Missense	proximal	-1	no	9.837	10.079	EPSD	TCGA;ICGC;COSMIC	5.915	Up-regulation
CMGC_MAPK_p38_MAPK14_ST	Q14721	KCNB1	Q16539	MAPK14	S520	S517L	517	Missense	distal	-3	no	9.837	8.105	EPSD	TCGA;ICGC;COSMIC;GDSC;CCLE	5.915	Down-regulation
CMGC_MAPK_p38_MAPK14_ST	Q14721	KCNB1	Q16539	MAPK14	S607	L612H	612	Missense	distal	5	no	7.581	7.524	EPSD	TCGA;ICGC	5.915	Down-regulation
CMGC_MAPK_p38_MAPK14_ST	Q14721	KCNB1	Q16539	MAPK14	S656	E655K	655	Missense	proximal	-1	no	9.831	9.892	EPSD	TCGA;ICGC;COSMIC	5.915	Up-regulation
CMGC_MAPK_p38_MAPK14_ST	Q14721	KCNB1	Q16539	MAPK14	S656	P657L	657	Missense	proximal	1	no	9.831	1.780	EPSD	TCGA;ICGC;COSMIC	5.915	Loss
CMGC_MAPK_p38_MAPK14_ST	Q14721	KCNB1	Q16539	MAPK14	S656	S651I	651	Missense	distal	-5	no	9.831	10.231	EPSD	TCGA;ICGC;COSMIC	5.915	Up-regulation
CMGC_MAPK_p38_MAPK14_ST	Q14721	KCNB1	Q16539	MAPK14	S720	S723Y	723	Missense	distal	3	no	11.321	11.363	EPSD	TCGA;ICGC;COSMIC	5.915	Up-regulation
CMGC_MAPK_p38_MAPK14_ST	Q14721	KCNB1	Q16539	MAPK14	S720	P721T	721	Missense	proximal	1	no	11.321	3.868	EPSD	TCGA;ICGC;COSMIC	5.915	Loss
CMGC_MAPK_p38_MAPK14_ST	Q14721	KCNB1	Q16539	MAPK14	S720	L713P	713	Missense	distal	-7	no	11.321	11.514	EPSD	TCGA;ICGC;COSMIC	5.915	Up-regulation
CMGC_MAPK_p38_MAPK14_ST	Q14721	KCNB1	Q16539	MAPK14	T728	S723Y	723	Missense	distal	-5	no	5.468	5.916	EPSD	TCGA;ICGC;COSMIC	5.915	Gain
CMGC_MAPK_p38_MAPK14_ST	Q14721	KCNB1	Q16539	MAPK14	S730	S723Y	723	Missense	distal	-7	no	6.555	5.994	EPSD	TCGA;ICGC;COSMIC	5.915	Down-regulation
CMGC_MAPK_p38_MAPK14_ST	Q14721	KCNB1	Q16539	MAPK14	S730	S737Y	737	Missense	distal	7	no	6.555	6.597	EPSD	TCGA;ICGC;COSMIC	5.915	Up-regulation
CMGC_MAPK_p38_MAPK14_ST	Q14721	KCNB1	Q16539	MAPK14	S730	K732N	732	Missense	proximal	2	no	6.555	6.648	EPSD	TCGA;ICGC	5.915	Up-regulation
CMGC_MAPK_p38_MAPK14_ST	Q14721	KCNB1	Q16539	MAPK14	T733	S737Y	737	Missense	distal	4	no	10.847	9.800	EPSD	TCGA;ICGC;COSMIC	5.915	Down-regulation
CMGC_MAPK_p38_MAPK14_ST	Q14721	KCNB1	Q16539	MAPK14	T733	K732N	732	Missense	proximal	-1	no	10.847	10.945	EPSD	TCGA;ICGC	5.915	Up-regulation
CMGC_MAPK_p38_MAPK14_ST	Q14721	KCNB1	Q16539	MAPK14	S737	S737Y	737	Missense	central	0	yes	11.876	0.000	EPSD	TCGA;ICGC;COSMIC	5.915	Loss
CMGC_MAPK_p38_MAPK14_ST	Q14721	KCNB1	Q16539	MAPK14	S737	K732N	732	Missense	distal	-5	no	11.876	12.256	EPSD	TCGA;ICGC	5.915	Up-regulation
CMGC_MAPK_p38_MAPK14_ST	Q14721	KCNB1	Q16539	MAPK14	S783	P779S	779	Missense	distal	-4	no	12.078	11.990	EPSD	TCGA;ICGC;COSMIC	5.915	Down-regulation
CMGC_MAPK_p38_MAPK14_ST	Q14721	KCNB1	Q16539	MAPK14	S783	P784S	784	Missense	proximal	1	no	12.078	4.794	EPSD	TCGA;ICGC;COSMIC	5.915	Loss
CMGC_MAPK_p38_MAPK14_ST	Q14721	KCNB1	Q16539	MAPK14	S783	T788M	788	Missense	distal	5	no	12.078	11.765	EPSD	TCGA;ICGC;COSMIC	5.915	Down-regulation
CMGC_MAPK_p38_MAPK14_ST	Q14721	KCNB1	Q16539	MAPK14	S800	F797V	797	Missense	distal	-3	no	11.299	12.093	PhosphoSitePlus;EPSD	TCGA;ICGC;COSMIC	5.915	Up-regulation
CMGC_MAPK_p38_MAPK14_ST	Q14721	KCNB1	Q16539	MAPK14	S800	S799R	799	Missense	proximal	-1	no	11.299	11.191	PhosphoSitePlus;EPSD	TCGA;ICGC;COSMIC	5.915	Down-regulation
CMGC_MAPK_p38_MAPK14_ST	Q14721	KCNB1	Q16539	MAPK14	S800	P803H	803	Missense	distal	3	no	11.299	11.358	PhosphoSitePlus;EPSD	TCGA;ICGC;COSMIC	5.915	Up-regulation
CMGC_MAPK_p38_MAPK14_ST	Q14721	KCNB1	Q16539	MAPK14	S800	F797I	797	Missense	distal	-3	no	11.299	11.934	PhosphoSitePlus;EPSD	TCGA;ICGC;COSMIC	5.915	Up-regulation
CMGC_MAPK_p38_MAPK14_ST	Q14721	KCNB1	Q16539	MAPK14	S805	S799R	799	Missense	distal	-6	no	12.550	12.444	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	5.915	Down-regulation
CMGC_MAPK_p38_MAPK14_ST	Q14721	KCNB1	Q16539	MAPK14	S805	P803H	803	Missense	proximal	-2	no	12.550	10.284	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	5.915	Down-regulation
CMGC_MAPK_p38_MAPK14_ST	Q14721	KCNB1	Q16539	MAPK14	S805	R810K	810	Missense	distal	5	no	12.550	12.255	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	5.915	Down-regulation
CMGC_MAPK_p38_MAPK14_ST	P28324	ELK4	Q16539	MAPK14	S180	E177D	177	Missense	distal	-3	no	10.005	9.799	EPSD	TCGA;ICGC;COSMIC	5.915	Down-regulation
CMGC_MAPK_p38_MAPK14_ST	P28324	ELK4	Q16539	MAPK14	S180	S180F	180	Missense	central	0	yes	10.005	0.000	EPSD	TCGA;ICGC;COSMIC	5.915	Loss
CMGC_MAPK_p38_MAPK14_ST	P28324	ELK4	Q16539	MAPK14	T185	K190R	190	Missense	distal	5	no	9.966	10.261	EPSD	TCGA;ICGC;COSMIC	5.915	Up-regulation
CMGC_MAPK_p38_MAPK14_ST	P28324	ELK4	Q16539	MAPK14	T185	S180F	180	Missense	distal	-5	no	9.966	10.751	EPSD	TCGA;ICGC;COSMIC	5.915	Up-regulation
CMGC_MAPK_p38_MAPK14_ST	P28324	ELK4	Q16539	MAPK14	T194	K190R	190	Missense	distal	-4	no	8.460	8.545	EPSD	TCGA;ICGC;COSMIC	5.915	Up-regulation
CMGC_MAPK_p38_MAPK14_ST	P28324	ELK4	Q16539	MAPK14	S215	S217C	217	Missense	proximal	2	no	12.470	12.058	EPSD	TCGA;ICGC;COSMIC	5.915	Down-regulation
CMGC_MAPK_p38_MAPK14_ST	P28324	ELK4	Q16539	MAPK14	S215	E219Q	219	Missense	distal	4	no	12.470	11.050	EPSD	TCGA;ICGC;COSMIC	5.915	Down-regulation
CMGC_MAPK_p38_MAPK14_ST	P28324	ELK4	Q16539	MAPK14	S215	I214F	214	Missense	proximal	-1	no	12.470	12.735	EPSD	TCGA;ICGC;COSMIC	5.915	Up-regulation
CMGC_MAPK_p38_MAPK14_ST	P28324	ELK4	Q16539	MAPK14	S215	G211D	211	Missense	distal	-4	no	12.470	12.966	EPSD	TCGA;ICGC;COSMIC	5.915	Up-regulation
CMGC_MAPK_p38_MAPK14_ST	P28324	ELK4	Q16539	MAPK14	S387	R390K	390	Missense	distal	3	no	12.952	12.969	PhosphoSitePlus;EPSD	TCGA;ICGC	5.915	Up-regulation
CMGC_MAPK_p38_MAPK14_ST	P28324	ELK4	Q16539	MAPK14	T420	D416G	416	Missense	distal	-4	no	13.640	13.145	EPSD	TCGA;ICGC;COSMIC	5.915	Down-regulation
CMGC_MAPK_p38_MAPK14_ST	P28324	ELK4	Q16539	MAPK14	T420	P418L	418	Missense	proximal	-2	no	13.640	12.260	EPSD	TCGA;ICGC;COSMIC	5.915	Down-regulation
CMGC_MAPK_p38_MAPK14_ST	P28324	ELK4	Q16539	MAPK14	S425	P418L	418	Missense	distal	-7	no	14.401	14.208	EPSD	TCGA;ICGC;COSMIC	5.915	Down-regulation
CMGC_MAPK_p38_MAPK14_ST	P04792	HSPB1	Q16539	MAPK14	S82	L81I	81	Missense	proximal	-1	no	7.365	7.065	EPSD	TCGA;ICGC;COSMIC	5.915	Down-regulation
CMGC_MAPK_p38_MAPK14_ST	P04792	HSPB1	Q16539	MAPK14	S158	E160K	160	Missense	proximal	2	no	14.484	14.169	EPSD	TCGA;ICGC;COSMIC	5.915	Down-regulation
CMGC_MAPK_p38_MAPK14_ST	P04792	HSPB1	Q16539	MAPK14	S158	S158F	158	Missense	central	0	yes	14.484	0.000	EPSD	TCGA	5.915	Loss
CMGC_MAPK_p38_MAPK14_ST	P04792	HSPB1	Q16539	MAPK14	S199	G192W	192	Missense	distal	-7	no	7.301	6.460	EPSD	TCGA;ICGC;COSMIC	5.915	Down-regulation
CMGC_MAPK_p38_MAPK14_ST	P03372	ESR1	Q16539	MAPK14	S118	P113S	113	Missense	distal	-5	no	10.058	9.611	PhosphoSitePlus;EPSD	TCGA;ICGC;COSMIC	5.915	Down-regulation
CMGC_MAPK_p38_MAPK14_ST	P03372	ESR1	Q16539	MAPK14	S282	G278C	278	Missense	distal	-4	no	5.641	6.105	EPSD	TCGA;ICGC;COSMIC	5.915	Gain
CMGC_MAPK_p38_MAPK14_ST	P03372	ESR1	Q16539	MAPK14	S294	W292R	292	Missense	proximal	-2	no	9.793	10.319	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	5.915	Up-regulation
CMGC_MAPK_p38_MAPK14_ST	P03372	ESR1	Q16539	MAPK14	S294	I298M	298	Missense	distal	4	no	9.793	10.258	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	5.915	Up-regulation
CMGC_MAPK_p38_MAPK14_ST	P03372	ESR1	Q16539	MAPK14	S294	L291I	291	Missense	distal	-3	no	9.793	9.453	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	5.915	Down-regulation
CMGC_MAPK_p38_MAPK14_ST	P03372	ESR1	Q16539	MAPK14	S341	P336T	336	Missense	distal	-5	no	6.264	6.257	EPSD	TCGA;ICGC;COSMIC	5.915	Down-regulation
CMGC_MAPK_p38_MAPK14_ST	P03372	ESR1	Q16539	MAPK14	S341	G344D	344	Missense	distal	3	no	6.264	6.274	EPSD	TCGA;ICGC;COSMIC	5.915	Up-regulation
CMGC_MAPK_p38_MAPK14_ST	P03372	ESR1	Q16539	MAPK14	S554	R548H	548	Missense	distal	-6	no	6.644	5.681	EPSD	TCGA;ICGC;COSMIC	5.915	Loss
CMGC_MAPK_p38_MAPK14_ST	P03372	ESR1	Q16539	MAPK14	S554	R548C	548	Missense	distal	-6	no	6.644	5.458	EPSD	TCGA;ICGC;COSMIC;GDSC;CCLE	5.915	Loss
CMGC_MAPK_p38_MAPK14_ST	P03372	ESR1	Q16539	MAPK14	S554	A551E	551	Missense	distal	-3	no	6.644	6.273	EPSD	TCGA;ICGC;COSMIC	5.915	Down-regulation
CMGC_MAPK_p38_MAPK14_ST	P03372	ESR1	Q16539	MAPK14	S554	A551V	551	Missense	distal	-3	no	6.644	5.143	EPSD	TCGA;ICGC;COSMIC;CCLE	5.915	Loss
CMGC_MAPK_p38_MAPK14_ST	P03372	ESR1	Q16539	MAPK14	S554	R555C	555	Missense	proximal	1	no	6.644	2.853	EPSD	TCGA;ICGC;COSMIC	5.915	Loss
CMGC_MAPK_p38_MAPK14_ST	P03372	ESR1	Q16539	MAPK14	S554	R555H	555	Missense	proximal	1	no	6.644	0.925	EPSD	TCGA;ICGC;COSMIC;GDSC	5.915	Loss
CMGC_MAPK_p38_MAPK14_ST	Q9H3D4	TP63	Q16539	MAPK14	S30	E33K	33	Missense	distal	3	no	6.858	6.906	EPSD	TCGA;ICGC;COSMIC	5.915	Up-regulation
CMGC_MAPK_p38_MAPK14_ST	Q9H3D4	TP63	Q16539	MAPK14	S30	R37Q	37	Missense	distal	7	no	6.858	6.664	EPSD	TCGA;ICGC;COSMIC	5.915	Down-regulation
CMGC_MAPK_p38_MAPK14_ST	Q9H3D4	TP63	Q16539	MAPK14	S30	V23I	23	Missense	distal	-7	no	6.858	7.142	EPSD	TCGA;ICGC;COSMIC	5.915	Up-regulation
CMGC_MAPK_p38_MAPK14_ST	Q9H3D4	TP63	Q16539	MAPK14	S51	I58T	58	Missense	distal	7	no	10.525	10.937	EPSD	TCGA;ICGC;COSMIC	5.915	Up-regulation
CMGC_MAPK_p38_MAPK14_ST	Q9H3D4	TP63	Q16539	MAPK14	S51	E53Q	53	Missense	proximal	2	no	10.525	9.988	EPSD	TCGA;ICGC;COSMIC	5.915	Down-regulation
CMGC_MAPK_p38_MAPK14_ST	Q9H3D4	TP63	Q16539	MAPK14	S160	P166L	166	Missense	distal	6	no	12.600	12.461	EPSD	TCGA;ICGC;COSMIC	5.915	Down-regulation
CMGC_MAPK_p38_MAPK14_ST	Q9H3D4	TP63	Q16539	MAPK14	S160	A164T	164	Missense	distal	4	no	12.600	12.644	EPSD	TCGA;COSMIC	5.915	Up-regulation
CMGC_MAPK_p38_MAPK14_ST	Q9H3D4	TP63	Q16539	MAPK14	S160	A164V	164	Missense	distal	4	no	12.600	12.166	EPSD	TCGA;ICGC;COSMIC	5.915	Down-regulation
CMGC_MAPK_p38_MAPK14_ST	Q9H3D4	TP63	Q16539	MAPK14	S160	P163L	163	Missense	distal	3	no	12.600	12.634	EPSD	TCGA;ICGC;COSMIC	5.915	Up-regulation
CMGC_MAPK_p38_MAPK14_ST	Q9H3D4	TP63	Q16539	MAPK14	S160	S153R	153	Missense	distal	-7	no	12.600	12.431	EPSD	TCGA;ICGC;COSMIC	5.915	Down-regulation
CMGC_MAPK_p38_MAPK14_ST	Q9H3D4	TP63	Q16539	MAPK14	S160	D157Y	157	Missense	distal	-3	no	12.600	12.694	EPSD	TCGA;ICGC;COSMIC	5.915	Up-regulation
CMGC_MAPK_p38_MAPK14_ST	Q9H3D4	TP63	Q16539	MAPK14	S162	P166L	166	Missense	distal	4	no	9.524	8.885	EPSD	TCGA;ICGC;COSMIC	5.915	Down-regulation
CMGC_MAPK_p38_MAPK14_ST	Q9H3D4	TP63	Q16539	MAPK14	S162	A164T	164	Missense	proximal	2	no	9.524	9.553	EPSD	TCGA;COSMIC	5.915	Up-regulation
CMGC_MAPK_p38_MAPK14_ST	Q9H3D4	TP63	Q16539	MAPK14	S162	A164V	164	Missense	proximal	2	no	9.524	9.361	EPSD	TCGA;ICGC;COSMIC	5.915	Down-regulation
CMGC_MAPK_p38_MAPK14_ST	Q9H3D4	TP63	Q16539	MAPK14	S162	P163L	163	Missense	proximal	1	no	9.524	1.474	EPSD	TCGA;ICGC;COSMIC	5.915	Loss
CMGC_MAPK_p38_MAPK14_ST	Q9H3D4	TP63	Q16539	MAPK14	S162	D157Y	157	Missense	distal	-5	no	9.524	9.349	EPSD	TCGA;ICGC;COSMIC	5.915	Down-regulation
CMGC_MAPK_p38_MAPK14_ST	Q9H3D4	TP63	Q16539	MAPK14	S389	Q386R	386	Missense	distal	-3	no	4.971	6.750	EPSD	TCGA;COSMIC	5.915	Gain
CMGC_MAPK_p38_MAPK14_ST	Q9H3D4	TP63	Q16539	MAPK14	S395	P396T	396	Missense	proximal	1	no	13.209	5.756	EPSD	TCGA;COSMIC	5.915	Loss
CMGC_MAPK_p38_MAPK14_ST	Q9H3D4	TP63	Q16539	MAPK14	S395	T388I	388	Missense	distal	-7	no	13.209	12.858	EPSD	TCGA;ICGC;COSMIC	5.915	Down-regulation
CMGC_MAPK_p38_MAPK14_ST	Q9H3D4	TP63	Q16539	MAPK14	S395	D398N	398	Missense	distal	3	no	13.209	13.203	EPSD	TCGA;ICGC;COSMIC	5.915	Down-regulation
CMGC_MAPK_p38_MAPK14_ST	Q9H3D4	TP63	Q16539	MAPK14	S395	S389F	389	Missense	distal	-6	no	13.209	11.445	EPSD	TCGA;ICGC;COSMIC	5.915	Down-regulation
CMGC_MAPK_p38_MAPK14_ST	Q9H3D4	TP63	Q16539	MAPK14	S395	D397G	397	Missense	proximal	2	no	13.209	13.466	EPSD	TCGA;COSMIC	5.915	Up-regulation
CMGC_MAPK_p38_MAPK14_ST	Q9H3D4	TP63	Q16539	MAPK14	S395	R393Q	393	Missense	proximal	-2	no	13.209	12.883	EPSD	TCGA;COSMIC	5.915	Down-regulation
CMGC_MAPK_p38_MAPK14_ST	Q9H3D4	TP63	Q16539	MAPK14	S395	K391N	391	Missense	distal	-4	no	13.209	13.356	EPSD	TCGA;COSMIC	5.915	Up-regulation
CMGC_MAPK_p38_MAPK14_ST	Q9H3D4	TP63	Q16539	MAPK14	S455	S458L	458	Missense	distal	3	no	10.132	10.206	EPSD	TCGA;COSMIC	5.915	Up-regulation
CMGC_MAPK_p38_MAPK14_ST	Q9H3D4	TP63	Q16539	MAPK14	S455	P456L	456	Missense	proximal	1	no	10.132	2.081	EPSD	TCGA;COSMIC	5.915	Loss
CMGC_MAPK_p38_MAPK14_ST	Q9H3D4	TP63	Q16539	MAPK14	S457	P456L	456	Missense	proximal	-1	no	5.888	6.073	EPSD	TCGA;COSMIC	5.915	Gain
CMGC_MAPK_p38_MAPK14_ST	Q9H3D4	TP63	Q16539	MAPK14	S463	P464L	464	Missense	proximal	1	no	11.330	3.280	EPSD	TCGA;COSMIC	5.915	Loss
CMGC_MAPK_p38_MAPK14_ST	Q9H3D4	TP63	Q16539	MAPK14	S463	M469I	469	Missense	distal	6	no	11.330	11.071	EPSD	TCGA;COSMIC	5.915	Down-regulation
CMGC_MAPK_p38_MAPK14_ST	Q9H3D4	TP63	Q16539	MAPK14	S463	N467S	467	Missense	distal	4	no	11.330	11.847	EPSD	TCGA;COSMIC	5.915	Up-regulation
CMGC_MAPK_p38_MAPK14_ST	Q9H3D4	TP63	Q16539	MAPK14	S463	S458L	458	Missense	distal	-5	no	11.330	12.060	EPSD	TCGA;COSMIC	5.915	Up-regulation
CMGC_MAPK_p38_MAPK14_ST	Q9H3D4	TP63	Q16539	MAPK14	S463	P456L	456	Missense	distal	-7	no	11.330	11.137	EPSD	TCGA;COSMIC	5.915	Down-regulation
CMGC_MAPK_p38_MAPK14_ST	Q9H3D4	TP63	Q16539	MAPK14	T491	P492A	492	Missense	proximal	1	no	6.592	0.274	EPSD	TCGA;COSMIC	5.915	Loss
CMGC_MAPK_p38_MAPK14_ST	Q9H3D4	TP63	Q16539	MAPK14	T491	P492S	492	Missense	proximal	1	no	6.592	-0.692	EPSD	TCGA;COSMIC	5.915	Loss
CMGC_MAPK_p38_MAPK14_ST	Q9H3D4	TP63	Q16539	MAPK14	T491	R487C	487	Missense	distal	-4	no	6.592	7.043	EPSD	TCGA;COSMIC	5.915	Up-regulation
CMGC_MAPK_p38_MAPK14_ST	Q9H3D4	TP63	Q16539	MAPK14	T491	P496S	496	Missense	distal	5	no	6.592	7.043	EPSD	TCGA;COSMIC	5.915	Up-regulation
CMGC_MAPK_p38_MAPK14_ST	Q9H3D4	TP63	Q16539	MAPK14	T491	R487S	487	Missense	distal	-4	no	6.592	6.581	EPSD	TCGA	5.915	Down-regulation
CMGC_MAPK_p38_MAPK14_ST	Q9H3D4	TP63	Q16539	MAPK14	T491	A489T	489	Missense	proximal	-2	no	6.592	6.535	EPSD	TCGA;COSMIC	5.915	Down-regulation
CMGC_MAPK_p38_MAPK14_ST	Q9H3D4	TP63	Q16539	MAPK14	T491	R487H	487	Missense	distal	-4	no	6.592	6.803	EPSD	TCGA;COSMIC	5.915	Up-regulation
CMGC_MAPK_p38_MAPK14_ST	Q9H3D4	TP63	Q16539	MAPK14	S551	A554S	554	Missense	distal	3	no	6.075	6.060	EPSD	TCGA;COSMIC	5.915	Down-regulation
CMGC_MAPK_p38_MAPK14_ST	Q9H3D4	TP63	Q16539	MAPK14	S551	R555W	555	Missense	distal	4	no	6.075	4.800	EPSD	TCGA;COSMIC	5.915	Loss
CMGC_MAPK_p38_MAPK14_ST	Q9H3D4	TP63	Q16539	MAPK14	S551	F552L	552	Missense	proximal	1	no	6.075	4.028	EPSD	TCGA;COSMIC;CCLE	5.915	Loss
CMGC_MAPK_p38_MAPK14_ST	Q9H3D4	TP63	Q16539	MAPK14	S551	D546N	546	Missense	distal	-5	no	6.075	5.915	EPSD	TCGA;COSMIC	5.915	Down-regulation
CMGC_MAPK_p38_MAPK14_ST	Q9H3D4	TP63	Q16539	MAPK14	S551	R555K	555	Missense	distal	4	no	6.075	6.826	EPSD	TCGA;COSMIC	5.915	Up-regulation
CMGC_MAPK_p38_MAPK14_ST	Q9H3D4	TP63	Q16539	MAPK14	S551	L553I	553	Missense	proximal	2	no	6.075	6.085	EPSD	TCGA;COSMIC	5.915	Up-regulation
CMGC_MAPK_p38_MAPK14_ST	Q9H3D4	TP63	Q16539	MAPK14	S612	E609K	609	Missense	distal	-3	no	11.479	11.087	EPSD	TCGA;COSMIC	5.915	Down-regulation
CMGC_MAPK_p38_MAPK14_ST	Q9H3D4	TP63	Q16539	MAPK14	S612	H615Y	615	Missense	distal	3	no	11.479	11.422	EPSD	TCGA;COSMIC	5.915	Down-regulation
CMGC_MAPK_p38_MAPK14_ST	Q9H3D4	TP63	Q16539	MAPK14	S612	F610L	610	Missense	proximal	-2	no	11.479	11.312	EPSD	TCGA;COSMIC	5.915	Down-regulation
CMGC_MAPK_p38_MAPK14_ST	Q9H3D4	TP63	Q16539	MAPK14	S614	H615Y	615	Missense	proximal	1	no	0.016	6.393	EPSD	TCGA;COSMIC	5.915	Gain
CMGC_MAPK_p38_MAPK14_ST	Q9H3D4	TP63	Q16539	MAPK14	T619	H615Y	615	Missense	distal	-4	no	8.101	7.876	EPSD	TCGA;COSMIC	5.915	Down-regulation
CMGC_MAPK_p38_MAPK14_ST	Q9H3D4	TP63	Q16539	MAPK14	S622	G629C	629	Missense	distal	7	no	6.872	6.450	EPSD	TCGA;COSMIC	5.915	Down-regulation
CMGC_MAPK_p38_MAPK14_ST	Q9H3D4	TP63	Q16539	MAPK14	S622	H615Y	615	Missense	distal	-7	no	6.872	6.775	EPSD	TCGA;COSMIC	5.915	Down-regulation
CMGC_MAPK_p38_MAPK14_ST	P29353	SHC1	Q16539	MAPK14	T29	E32D	32	Missense	distal	3	no	11.108	11.163	EPSD	TCGA;ICGC	5.915	Up-regulation
CMGC_MAPK_p38_MAPK14_ST	P29353	SHC1	Q16539	MAPK14	S36	E32D	32	Missense	distal	-4	no	11.449	12.241	EPSD	TCGA;ICGC	5.915	Up-regulation
CMGC_MAPK_p38_MAPK14_ST	P29353	SHC1	Q16539	MAPK14	S54	P55L	55	Missense	proximal	1	no	9.645	1.594	PhosphoSitePlus;EPSD	TCGA;ICGC;COSMIC	5.915	Loss
CMGC_MAPK_p38_MAPK14_ST	P29353	SHC1	Q16539	MAPK14	S54	D53N	53	Missense	proximal	-1	no	9.645	9.459	PhosphoSitePlus;EPSD	TCGA;ICGC;COSMIC	5.915	Down-regulation
CMGC_MAPK_p38_MAPK14_ST	P29353	SHC1	Q16539	MAPK14	S139	R146Q	146	Missense	distal	7	no	8.842	8.648	EPSD	TCGA;COSMIC	5.915	Down-regulation
CMGC_MAPK_p38_MAPK14_ST	P29353	SHC1	Q16539	MAPK14	S139	H137L	137	Missense	proximal	-2	no	8.842	9.728	EPSD	TCGA;COSMIC	5.915	Up-regulation
CMGC_MAPK_p38_MAPK14_ST	P29353	SHC1	Q16539	MAPK14	T386	P387S	387	Missense	proximal	1	no	9.374	2.090	EPSD;PhosphoSitePlus	TCGA;COSMIC	5.915	Loss
CMGC_MAPK_p38_MAPK14_ST	Q86UR1	NOXA1	Q16539	MAPK14	S239	S239F	239	Missense	central	0	yes	10.653	0.000	PhosphoSitePlus;EPSD	TCGA;ICGC	5.915	Loss
CMGC_MAPK_p38_MAPK14_ST	Q86UR1	NOXA1	Q16539	MAPK14	S282	G289E	289	Missense	distal	7	no	10.991	11.352	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	5.915	Up-regulation
CMGC_MAPK_p38_MAPK14_ST	P41212	ETV6	Q16539	MAPK14	T4	K11N	11	Missense	distal	7	no	9.364	9.554	EPSD	TCGA;ICGC;COSMIC	5.915	Up-regulation
CMGC_MAPK_p38_MAPK14_ST	P41212	ETV6	Q16539	MAPK14	T4	A6V	6	Missense	proximal	2	no	9.364	9.200	EPSD	TCGA;ICGC;COSMIC	5.915	Down-regulation
CMGC_MAPK_p38_MAPK14_ST	P41212	ETV6	Q16539	MAPK14	T18	K11N	11	Missense	distal	-7	no	6.916	6.608	EPSD	TCGA;ICGC;COSMIC	5.915	Down-regulation
CMGC_MAPK_p38_MAPK14_ST	P41212	ETV6	Q16539	MAPK14	T18	S22C	22	Missense	distal	4	no	6.916	5.765	EPSD	TCGA;ICGC;COSMIC	5.915	Loss
CMGC_MAPK_p38_MAPK14_ST	P41212	ETV6	Q16539	MAPK14	T18	P19H	19	Missense	proximal	1	no	6.916	-6.738	EPSD	TCGA;ICGC;COSMIC	5.915	Loss
CMGC_MAPK_p38_MAPK14_ST	P41212	ETV6	Q16539	MAPK14	T18	R14Q	14	Missense	distal	-4	no	6.916	7.284	EPSD	TCGA;ICGC;COSMIC	5.915	Up-regulation
CMGC_MAPK_p38_MAPK14_ST	P41212	ETV6	Q16539	MAPK14	S22	S22C	22	Missense	central	0	yes	12.051	0.000	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	5.915	Loss
CMGC_MAPK_p38_MAPK14_ST	P41212	ETV6	Q16539	MAPK14	S22	P19H	19	Missense	distal	-3	no	12.051	11.574	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	5.915	Down-regulation
CMGC_MAPK_p38_MAPK14_ST	P41212	ETV6	Q16539	MAPK14	S22	A28T	28	Missense	distal	6	no	12.051	12.034	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	5.915	Down-regulation
CMGC_MAPK_p38_MAPK14_ST	P41212	ETV6	Q16539	MAPK14	T31	A28T	28	Missense	distal	-3	no	8.234	8.328	EPSD	TCGA;ICGC;COSMIC	5.915	Up-regulation
CMGC_MAPK_p38_MAPK14_ST	P41212	ETV6	Q16539	MAPK14	S131	L129I	129	Missense	proximal	-2	no	10.736	11.298	EPSD	TCGA;ICGC;COSMIC	5.915	Up-regulation
CMGC_MAPK_p38_MAPK14_ST	P41212	ETV6	Q16539	MAPK14	S131	G137E	137	Missense	distal	6	no	10.736	10.695	EPSD	TCGA;ICGC;COSMIC	5.915	Down-regulation
CMGC_MAPK_p38_MAPK14_ST	P41212	ETV6	Q16539	MAPK14	S131	L129P	129	Missense	proximal	-2	no	10.736	12.116	EPSD	TCGA;ICGC;COSMIC	5.915	Up-regulation
CMGC_MAPK_p38_MAPK14_ST	P41212	ETV6	Q16539	MAPK14	S184	R191Q	191	Missense	distal	7	no	12.096	11.903	EPSD	TCGA;ICGC;COSMIC;GDSC;CCLE	5.915	Down-regulation
CMGC_MAPK_p38_MAPK14_ST	P41212	ETV6	Q16539	MAPK14	S184	R181L	181	Missense	distal	-3	no	12.096	9.853	EPSD	TCGA;ICGC;COSMIC	5.915	Down-regulation
CMGC_MAPK_p38_MAPK14_ST	P41212	ETV6	Q16539	MAPK14	S184	R181C	181	Missense	distal	-3	no	12.096	9.901	EPSD	TCGA;ICGC;COSMIC	5.915	Down-regulation
CMGC_MAPK_p38_MAPK14_ST	P41212	ETV6	Q16539	MAPK14	S184	R183M	183	Missense	proximal	-1	no	12.096	12.327	EPSD	TCGA;ICGC;COSMIC	5.915	Up-regulation
CMGC_MAPK_p38_MAPK14_ST	P41212	ETV6	Q16539	MAPK14	S193	R191Q	191	Missense	proximal	-2	no	12.269	11.942	EPSD	TCGA;ICGC;COSMIC;GDSC;CCLE	5.915	Down-regulation
CMGC_MAPK_p38_MAPK14_ST	P41212	ETV6	Q16539	MAPK14	S193	P194S	194	Missense	proximal	1	no	12.269	4.985	EPSD	TCGA;ICGC;COSMIC;GDSC;CCLE	5.915	Loss
CMGC_MAPK_p38_MAPK14_ST	P41212	ETV6	Q16539	MAPK14	S193	R199Q	199	Missense	distal	6	no	12.269	12.281	EPSD	TCGA;ICGC;COSMIC	5.915	Up-regulation
CMGC_MAPK_p38_MAPK14_ST	P41212	ETV6	Q16539	MAPK14	S203	R202L	202	Missense	proximal	-1	no	9.812	10.198	EPSD	TCGA;ICGC;COSMIC	5.915	Up-regulation
CMGC_MAPK_p38_MAPK14_ST	P41212	ETV6	Q16539	MAPK14	S203	P204L	204	Missense	proximal	1	no	9.812	1.761	EPSD	TCGA;ICGC;COSMIC	5.915	Loss
CMGC_MAPK_p38_MAPK14_ST	P41212	ETV6	Q16539	MAPK14	S203	R210C	210	Missense	distal	7	no	9.812	9.213	EPSD	TCGA;ICGC;COSMIC	5.915	Down-regulation
CMGC_MAPK_p38_MAPK14_ST	P41212	ETV6	Q16539	MAPK14	S203	R199Q	199	Missense	distal	-4	no	9.812	10.180	EPSD	TCGA;ICGC;COSMIC	5.915	Up-regulation
CMGC_MAPK_p38_MAPK14_ST	P41212	ETV6	Q16539	MAPK14	S213	P214L	214	Missense	proximal	1	no	9.084	1.033	EPSD	TCGA;ICGC;COSMIC;CCLE	5.915	Loss
CMGC_MAPK_p38_MAPK14_ST	P41212	ETV6	Q16539	MAPK14	S213	R217T	217	Missense	distal	4	no	9.084	9.540	EPSD	TCGA;ICGC;COSMIC	5.915	Up-regulation
CMGC_MAPK_p38_MAPK14_ST	P41212	ETV6	Q16539	MAPK14	S213	R210C	210	Missense	distal	-3	no	9.084	6.888	EPSD	TCGA;ICGC;COSMIC	5.915	Down-regulation
CMGC_MAPK_p38_MAPK14_ST	P41212	ETV6	Q16539	MAPK14	S213	R211H	211	Missense	proximal	-2	no	9.084	7.506	EPSD	TCGA;ICGC;COSMIC	5.915	Down-regulation
CMGC_MAPK_p38_MAPK14_ST	P41212	ETV6	Q16539	MAPK14	S213	Q219R	219	Missense	distal	6	no	9.084	9.072	EPSD	TCGA;ICGC;COSMIC	5.915	Down-regulation
CMGC_MAPK_p38_MAPK14_ST	P41212	ETV6	Q16539	MAPK14	S238	E241K	241	Missense	distal	3	no	11.284	11.332	EPSD	TCGA;ICGC;COSMIC	5.915	Up-regulation
CMGC_MAPK_p38_MAPK14_ST	P41212	ETV6	Q16539	MAPK14	S238	S238Y	238	Missense	central	0	yes	11.284	0.000	EPSD	TCGA;ICGC;COSMIC	5.915	Loss
CMGC_MAPK_p38_MAPK14_ST	P41212	ETV6	Q16539	MAPK14	S257	P253L	253	Missense	distal	-4	no	13.479	13.991	PhosphoSitePlus;EPSD	TCGA;ICGC;COSMIC	5.915	Up-regulation
CMGC_MAPK_p38_MAPK14_ST	P41212	ETV6	Q16539	MAPK14	S323	E327Q	327	Missense	distal	4	no	9.215	7.794	EPSD	TCGA;ICGC;COSMIC	5.915	Down-regulation
CMGC_MAPK_p38_MAPK14_ST	P41212	ETV6	Q16539	MAPK14	T431	R433H	433	Missense	proximal	2	no	6.316	5.934	EPSD	TCGA;ICGC;COSMIC	5.915	Down-regulation
CMGC_MAPK_p38_MAPK14_ST	P19419	ELK1	Q16539	MAPK14	T133	P134L	134	Missense	proximal	1	no	8.653	0.602	EPSD	TCGA;ICGC	5.915	Loss
CMGC_MAPK_p38_MAPK14_ST	P19419	ELK1	Q16539	MAPK14	S196	S194L	194	Missense	proximal	-2	no	6.708	5.817	EPSD	TCGA;ICGC;COSMIC	5.915	Loss
CMGC_MAPK_p38_MAPK14_ST	P19419	ELK1	Q16539	MAPK14	S196	S196R	196	Missense	central	0	yes	6.708	0.000	EPSD	TCGA;ICGC;COSMIC	5.915	Loss
CMGC_MAPK_p38_MAPK14_ST	P19419	ELK1	Q16539	MAPK14	S196	P201L	201	Missense	distal	5	no	6.708	6.211	EPSD	TCGA;ICGC;COSMIC	5.915	Down-regulation
CMGC_MAPK_p38_MAPK14_ST	P19419	ELK1	Q16539	MAPK14	S196	G195R	195	Missense	proximal	-1	no	6.708	6.388	EPSD	TCGA;COSMIC	5.915	Down-regulation
CMGC_MAPK_p38_MAPK14_ST	P19419	ELK1	Q16539	MAPK14	S196	A189T	189	Missense	distal	-7	no	6.708	6.525	EPSD	TCGA;ICGC;COSMIC	5.915	Down-regulation
CMGC_MAPK_p38_MAPK14_ST	P19419	ELK1	Q16539	MAPK14	S200	S194L	194	Missense	distal	-6	no	12.391	11.171	EPSD	TCGA;ICGC;COSMIC	5.915	Down-regulation
CMGC_MAPK_p38_MAPK14_ST	P19419	ELK1	Q16539	MAPK14	S200	S196R	196	Missense	distal	-4	no	12.391	12.401	EPSD	TCGA;ICGC;COSMIC	5.915	Up-regulation
CMGC_MAPK_p38_MAPK14_ST	P19419	ELK1	Q16539	MAPK14	S200	P201L	201	Missense	proximal	1	no	12.391	4.340	EPSD	TCGA;ICGC;COSMIC	5.915	Loss
CMGC_MAPK_p38_MAPK14_ST	P19419	ELK1	Q16539	MAPK14	S200	G195R	195	Missense	distal	-5	no	12.391	12.228	EPSD	TCGA;COSMIC	5.915	Down-regulation
CMGC_MAPK_p38_MAPK14_ST	P19419	ELK1	Q16539	MAPK14	S202	S196R	196	Missense	distal	-6	no	10.282	10.176	EPSD	TCGA;ICGC;COSMIC	5.915	Down-regulation
CMGC_MAPK_p38_MAPK14_ST	P19419	ELK1	Q16539	MAPK14	S202	P201L	201	Missense	proximal	-1	no	10.282	10.467	EPSD	TCGA;ICGC;COSMIC	5.915	Up-regulation
CMGC_MAPK_p38_MAPK14_ST	P19419	ELK1	Q16539	MAPK14	S202	G195R	195	Missense	distal	-7	no	10.282	10.180	EPSD	TCGA;COSMIC	5.915	Down-regulation
CMGC_MAPK_p38_MAPK14_ST	P19419	ELK1	Q16539	MAPK14	T222	P224S	224	Missense	proximal	2	no	10.977	11.354	EPSD	TCGA;ICGC;COSMIC	5.915	Up-regulation
CMGC_MAPK_p38_MAPK14_ST	P19419	ELK1	Q16539	MAPK14	T222	E225K	225	Missense	distal	3	no	10.977	11.025	EPSD	TCGA;ICGC;COSMIC	5.915	Up-regulation
CMGC_MAPK_p38_MAPK14_ST	P19419	ELK1	Q16539	MAPK14	S304	S308C	308	Missense	distal	4	no	11.437	10.286	EPSD	TCGA;ICGC;COSMIC	5.915	Down-regulation
CMGC_MAPK_p38_MAPK14_ST	P19419	ELK1	Q16539	MAPK14	S304	A301V	301	Missense	distal	-3	no	11.437	9.936	EPSD	TCGA;ICGC	5.915	Down-regulation
CMGC_MAPK_p38_MAPK14_ST	P19419	ELK1	Q16539	MAPK14	S304	G298V	298	Missense	distal	-6	no	11.437	10.887	EPSD	TCGA;ICGC;COSMIC	5.915	Down-regulation
CMGC_MAPK_p38_MAPK14_ST	P19419	ELK1	Q16539	MAPK14	S304	S303Y	303	Missense	proximal	-1	no	11.437	11.438	EPSD	TCGA;ICGC;COSMIC	5.915	Up-regulation
CMGC_MAPK_p38_MAPK14_ST	P19419	ELK1	Q16539	MAPK14	S324	S324N	324	Missense	central	0	yes	11.186	0.000	EPSD	TCGA;ICGC;COSMIC	5.915	Loss
CMGC_MAPK_p38_MAPK14_ST	P19419	ELK1	Q16539	MAPK14	S324	P325L	325	Missense	proximal	1	no	11.186	3.135	EPSD	TCGA;ICGC	5.915	Loss
CMGC_MAPK_p38_MAPK14_ST	P19419	ELK1	Q16539	MAPK14	T353	A351V	351	Missense	proximal	-2	no	9.167	8.753	EPSD	TCGA;ICGC;COSMIC	5.915	Down-regulation
CMGC_MAPK_p38_MAPK14_ST	P19419	ELK1	Q16539	MAPK14	T368	L372Q	372	Missense	distal	4	no	6.828	6.986	EPSD	TCGA;ICGC	5.915	Up-regulation
CMGC_MAPK_p38_MAPK14_ST	P19419	ELK1	Q16539	MAPK14	S383	W379C	379	Missense	distal	-4	no	11.683	11.504	EPSD;PhosphoSitePlus	TCGA	5.915	Down-regulation
CMGC_MAPK_p38_MAPK14_ST	P19419	ELK1	Q16539	MAPK14	S383	F378L	378	Missense	distal	-5	no	11.683	11.627	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	5.915	Down-regulation
CMGC_MAPK_p38_MAPK14_ST	P19419	ELK1	Q16539	MAPK14	S389	S383T	383	Missense	distal	-6	no	13.211	12.938	PhosphoSitePlus;EPSD	TCGA;COSMIC	5.915	Down-regulation
CMGC_MAPK_p38_MAPK14_ST	P19419	ELK1	Q16539	MAPK14	S389	A391D	391	Missense	proximal	2	no	13.211	12.989	PhosphoSitePlus;EPSD	TCGA;ICGC	5.915	Down-regulation
CMGC_MAPK_p38_MAPK14_ST	P19419	ELK1	Q16539	MAPK14	S422	K427R	427	Missense	distal	5	no	12.846	13.140	EPSD	TCGA;ICGC;COSMIC	5.915	Up-regulation
CMGC_MAPK_p38_MAPK14_ST	P21462	FPR1	Q16539	MAPK14	S332	D333Y	333	Missense	proximal	1	no	6.497	6.652	EPSD	TCGA;ICGC;COSMIC	5.915	Up-regulation
CMGC_MAPK_p38_MAPK14_ST	P21462	FPR1	Q16539	MAPK14	S332	E326K	326	Missense	distal	-6	no	6.497	6.083	EPSD	TCGA;ICGC;COSMIC;GDSC;CCLE	5.915	Down-regulation
CMGC_MAPK_p38_MAPK14_ST	P21462	FPR1	Q16539	MAPK14	S338	D333Y	333	Missense	distal	-5	no	6.555	6.380	EPSD	TCGA;ICGC;COSMIC	5.915	Down-regulation
CMGC_MAPK_p38_MAPK14_ST	Q9UBK2	PPARGC1A	Q16539	MAPK14	S208	L211I	211	Missense	distal	3	no	6.703	6.726	EPSD	TCGA;ICGC;COSMIC	5.915	Up-regulation
CMGC_MAPK_p38_MAPK14_ST	Q9UBK2	PPARGC1A	Q16539	MAPK14	S208	R205L	205	Missense	distal	-3	no	6.703	4.460	EPSD	TCGA;ICGC;COSMIC	5.915	Loss
CMGC_MAPK_p38_MAPK14_ST	Q9UBK2	PPARGC1A	Q16539	MAPK14	S208	R205C	205	Missense	distal	-3	no	6.703	4.508	EPSD	TCGA;ICGC;COSMIC	5.915	Loss
CMGC_MAPK_p38_MAPK14_ST	Q9UBK2	PPARGC1A	Q16539	MAPK14	S259	L260F	260	Missense	proximal	1	no	4.101	6.149	EPSD	TCGA;ICGC;COSMIC	5.915	Gain
CMGC_MAPK_p38_MAPK14_ST	Q9UBK2	PPARGC1A	Q16539	MAPK14	T263	T256A	256	Missense	distal	-7	no	10.737	10.920	PhosphoSitePlus;EPSD	TCGA;ICGC;COSMIC	5.915	Up-regulation
CMGC_MAPK_p38_MAPK14_ST	Q9UBK2	PPARGC1A	Q16539	MAPK14	T263	P261S	261	Missense	proximal	-2	no	10.737	10.248	PhosphoSitePlus;EPSD	TCGA;ICGC;COSMIC	5.915	Down-regulation
CMGC_MAPK_p38_MAPK14_ST	Q9UBK2	PPARGC1A	Q16539	MAPK14	T263	P270L	270	Missense	distal	7	no	10.737	10.574	PhosphoSitePlus;EPSD	TCGA;ICGC;COSMIC	5.915	Down-regulation
CMGC_MAPK_p38_MAPK14_ST	Q9UBK2	PPARGC1A	Q16539	MAPK14	T263	L260F	260	Missense	distal	-3	no	10.737	9.761	PhosphoSitePlus;EPSD	TCGA;ICGC;COSMIC	5.915	Down-regulation
CMGC_MAPK_p38_MAPK14_ST	Q9UBK2	PPARGC1A	Q16539	MAPK14	T263	S259F	259	Missense	distal	-4	no	10.737	11.441	PhosphoSitePlus;EPSD	TCGA;ICGC;COSMIC	5.915	Up-regulation
CMGC_MAPK_p38_MAPK14_ST	Q9UBK2	PPARGC1A	Q16539	MAPK14	T263	D269G	269	Missense	distal	6	no	10.737	10.878	PhosphoSitePlus;EPSD	TCGA	5.915	Up-regulation
CMGC_MAPK_p38_MAPK14_ST	Q9UBK2	PPARGC1A	Q16539	MAPK14	S266	P261S	261	Missense	distal	-5	no	12.144	11.696	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	5.915	Down-regulation
CMGC_MAPK_p38_MAPK14_ST	Q9UBK2	PPARGC1A	Q16539	MAPK14	S266	P270L	270	Missense	distal	4	no	12.144	11.505	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	5.915	Down-regulation
CMGC_MAPK_p38_MAPK14_ST	Q9UBK2	PPARGC1A	Q16539	MAPK14	S266	L260F	260	Missense	distal	-6	no	12.144	11.599	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	5.915	Down-regulation
CMGC_MAPK_p38_MAPK14_ST	Q9UBK2	PPARGC1A	Q16539	MAPK14	S266	S259F	259	Missense	distal	-7	no	12.144	11.398	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	5.915	Down-regulation
CMGC_MAPK_p38_MAPK14_ST	Q9UBK2	PPARGC1A	Q16539	MAPK14	S266	D269G	269	Missense	distal	3	no	12.144	12.134	EPSD;PhosphoSitePlus	TCGA	5.915	Down-regulation
CMGC_MAPK_p38_MAPK14_ST	Q9UBK2	PPARGC1A	Q16539	MAPK14	S273	P270L	270	Missense	distal	-3	no	10.394	9.427	EPSD	TCGA;ICGC;COSMIC	5.915	Down-regulation
CMGC_MAPK_p38_MAPK14_ST	Q9UBK2	PPARGC1A	Q16539	MAPK14	S273	E276K	276	Missense	distal	3	no	10.394	10.442	EPSD	TCGA;ICGC;COSMIC	5.915	Up-regulation
CMGC_MAPK_p38_MAPK14_ST	Q9UBK2	PPARGC1A	Q16539	MAPK14	S273	D269G	269	Missense	distal	-4	no	10.394	9.899	EPSD	TCGA	5.915	Down-regulation
CMGC_MAPK_p38_MAPK14_ST	Q9UBK2	PPARGC1A	Q16539	MAPK14	T295	G293V	293	Missense	proximal	-2	no	10.068	9.930	EPSD	TCGA;ICGC;COSMIC	5.915	Down-regulation
CMGC_MAPK_p38_MAPK14_ST	Q9UBK2	PPARGC1A	Q16539	MAPK14	T295	P300S	300	Missense	distal	5	no	10.068	10.519	EPSD	TCGA;ICGC;COSMIC	5.915	Up-regulation
CMGC_MAPK_p38_MAPK14_ST	Q9UBK2	PPARGC1A	Q16539	MAPK14	T299	N305I	305	Missense	distal	6	no	12.244	12.054	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	5.915	Down-regulation
CMGC_MAPK_p38_MAPK14_ST	Q9UBK2	PPARGC1A	Q16539	MAPK14	T299	G293V	293	Missense	distal	-6	no	12.244	11.695	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	5.915	Down-regulation
CMGC_MAPK_p38_MAPK14_ST	Q9UBK2	PPARGC1A	Q16539	MAPK14	T299	K303R	303	Missense	distal	4	no	12.244	11.493	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	5.915	Down-regulation
CMGC_MAPK_p38_MAPK14_ST	Q9UBK2	PPARGC1A	Q16539	MAPK14	T299	P300S	300	Missense	proximal	1	no	12.244	4.960	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	5.915	Loss
CMGC_MAPK_p38_MAPK14_ST	Q9UBK2	PPARGC1A	Q16539	MAPK14	T299	A304D	304	Missense	distal	5	no	12.244	12.339	EPSD;PhosphoSitePlus	TCGA;ICGC	5.915	Up-regulation
CMGC_MAPK_p38_MAPK14_ST	Q9UBK2	PPARGC1A	Q16539	MAPK14	S313	S313F	313	Missense	central	0	yes	10.028	0.000	EPSD	TCGA;ICGC;COSMIC	5.915	Loss
CMGC_MAPK_p38_MAPK14_ST	Q9UBK2	PPARGC1A	Q16539	MAPK14	S313	C320F	320	Missense	distal	7	no	10.028	9.723	EPSD	TCGA;ICGC;COSMIC	5.915	Down-regulation
CMGC_MAPK_p38_MAPK14_ST	Q9UBK2	PPARGC1A	Q16539	MAPK14	S313	S313Y	313	Missense	central	0	yes	10.028	0.000	EPSD	TCGA;ICGC	5.915	Loss
CMGC_MAPK_p38_MAPK14_ST	Q9UBK2	PPARGC1A	Q16539	MAPK14	S552	S550Y	550	Missense	proximal	-2	no	9.770	9.772	EPSD	TCGA;ICGC	5.915	Up-regulation
CMGC_MAPK_p38_MAPK14_ST	Q9UBK2	PPARGC1A	Q16539	MAPK14	S552	D549V	549	Missense	distal	-3	no	9.770	8.846	EPSD	TCGA;ICGC;COSMIC	5.915	Down-regulation
CMGC_MAPK_p38_MAPK14_ST	Q9UBK2	PPARGC1A	Q16539	MAPK14	S552	D549N	549	Missense	distal	-3	no	9.770	9.611	EPSD	TCGA;ICGC;COSMIC	5.915	Down-regulation
CMGC_MAPK_p38_MAPK14_ST	Q9UBK2	PPARGC1A	Q16539	MAPK14	S552	C547Y	547	Missense	distal	-5	no	9.770	9.517	EPSD	TCGA;ICGC;COSMIC	5.915	Down-regulation
CMGC_MAPK_p38_MAPK14_ST	Q9UBK2	PPARGC1A	Q16539	MAPK14	S573	R568H	568	Missense	distal	-5	no	5.478	6.021	EPSD	TCGA;ICGC;COSMIC;CCLE	5.915	Gain
CMGC_MAPK_p38_MAPK14_ST	Q9UBK2	PPARGC1A	Q16539	MAPK14	S581	R585K	585	Missense	distal	4	no	6.410	7.160	EPSD	TCGA;ICGC;COSMIC	5.915	Up-regulation
CMGC_MAPK_p38_MAPK14_ST	Q9UBK2	PPARGC1A	Q16539	MAPK14	S581	S584F	584	Missense	distal	3	no	6.410	6.518	EPSD	TCGA;ICGC;COSMIC	5.915	Up-regulation
CMGC_MAPK_p38_MAPK14_ST	Q9UBK2	PPARGC1A	Q16539	MAPK14	S586	R585K	585	Missense	proximal	-1	no	6.449	6.530	EPSD	TCGA;ICGC;COSMIC	5.915	Up-regulation
CMGC_MAPK_p38_MAPK14_ST	Q9UBK2	PPARGC1A	Q16539	MAPK14	S586	S584F	584	Missense	proximal	-2	no	6.449	5.725	EPSD	TCGA;ICGC;COSMIC	5.915	Loss
CMGC_MAPK_p38_MAPK14_ST	Q9UBK2	PPARGC1A	Q16539	MAPK14	S590	R594I	594	Missense	distal	4	no	12.770	12.698	EPSD	TCGA;ICGC;COSMIC	5.915	Down-regulation
CMGC_MAPK_p38_MAPK14_ST	Q9UBK2	PPARGC1A	Q16539	MAPK14	S590	R585K	585	Missense	distal	-5	no	12.770	12.635	EPSD	TCGA;ICGC;COSMIC	5.915	Down-regulation
CMGC_MAPK_p38_MAPK14_ST	Q9UBK2	PPARGC1A	Q16539	MAPK14	S590	S584F	584	Missense	distal	-6	no	12.770	11.006	EPSD	TCGA;ICGC;COSMIC	5.915	Down-regulation
CMGC_MAPK_p38_MAPK14_ST	Q9UBK2	PPARGC1A	Q16539	MAPK14	S590	S597A	597	Missense	distal	7	no	12.770	12.793	EPSD	TCGA;ICGC	5.915	Up-regulation
CMGC_MAPK_p38_MAPK14_ST	Q9UBK2	PPARGC1A	Q16539	MAPK14	S593	R594I	594	Missense	proximal	1	no	7.958	8.215	EPSD	TCGA;ICGC;COSMIC	5.915	Up-regulation
CMGC_MAPK_p38_MAPK14_ST	Q9UBK2	PPARGC1A	Q16539	MAPK14	S593	S597A	597	Missense	distal	4	no	7.958	7.653	EPSD	TCGA;ICGC	5.915	Down-regulation
CMGC_MAPK_p38_MAPK14_ST	Q9UBK2	PPARGC1A	Q16539	MAPK14	S616	R609I	609	Missense	distal	-7	no	9.507	9.255	EPSD	TCGA;ICGC;COSMIC	5.915	Down-regulation
CMGC_MAPK_p38_MAPK14_ST	Q9UBK2	PPARGC1A	Q16539	MAPK14	S616	S616Y	616	Missense	central	0	yes	9.507	0.000	EPSD	TCGA;ICGC;COSMIC	5.915	Loss
CMGC_MAPK_p38_MAPK14_ST	Q9UBK2	PPARGC1A	Q16539	MAPK14	S616	R614Q	614	Missense	proximal	-2	no	9.507	9.180	EPSD	TCGA;ICGC;COSMIC	5.915	Down-regulation
CMGC_MAPK_p38_MAPK14_ST	Q9UBK2	PPARGC1A	Q16539	MAPK14	S626	R631W	631	Missense	distal	5	no	8.968	8.074	EPSD	TCGA;ICGC;COSMIC	5.915	Down-regulation
CMGC_MAPK_p38_MAPK14_ST	Q9UBK2	PPARGC1A	Q16539	MAPK14	S626	R630H	630	Missense	distal	4	no	8.968	8.575	EPSD	TCGA;ICGC;COSMIC;GDSC;CCLE	5.915	Down-regulation
CMGC_MAPK_p38_MAPK14_ST	Q9UBK2	PPARGC1A	Q16539	MAPK14	S626	S626L	626	Missense	central	0	yes	8.968	0.000	EPSD	TCGA;ICGC;COSMIC	5.915	Loss
CMGC_MAPK_p38_MAPK14_ST	O43526	KCNQ2	Q16539	MAPK14	S45	A39T	39	Missense	distal	-6	no	6.123	6.393	EPSD	TCGA	5.915	Up-regulation
CMGC_MAPK_p38_MAPK14_ST	O43526	KCNQ2	Q16539	MAPK14	S457	A460D	460	Missense	distal	3	no	8.506	8.542	EPSD	TCGA;COSMIC	5.915	Up-regulation
CMGC_MAPK_p38_MAPK14_ST	O43526	KCNQ2	Q16539	MAPK14	S457	G456R	456	Missense	proximal	-1	no	8.506	8.185	EPSD	TCGA;COSMIC	5.915	Down-regulation
CMGC_MAPK_p38_MAPK14_ST	O43526	KCNQ2	Q16539	MAPK14	S466	A460D	460	Missense	distal	-6	no	9.429	9.222	EPSD	TCGA;COSMIC	5.915	Down-regulation
CMGC_MAPK_p38_MAPK14_ST	O43526	KCNQ2	Q16539	MAPK14	S466	D470N	470	Missense	distal	4	no	9.429	10.082	EPSD	TCGA;COSMIC	5.915	Up-regulation
CMGC_MAPK_p38_MAPK14_ST	O43526	KCNQ2	Q16539	MAPK14	S468	D470N	470	Missense	proximal	2	no	7.928	8.158	EPSD	TCGA;COSMIC	5.915	Up-regulation
CMGC_MAPK_p38_MAPK14_ST	O43526	KCNQ2	Q16539	MAPK14	S468	E474Q	474	Missense	distal	6	no	7.928	7.860	EPSD	TCGA;COSMIC	5.915	Down-regulation
CMGC_MAPK_p38_MAPK14_ST	O43526	KCNQ2	Q16539	MAPK14	S468	D475N	475	Missense	distal	7	no	7.928	7.607	EPSD	TCGA;COSMIC	5.915	Down-regulation
CMGC_MAPK_p38_MAPK14_ST	O43526	KCNQ2	Q16539	MAPK14	S476	D470N	470	Missense	distal	-6	no	9.203	9.529	EPSD	TCGA;COSMIC	5.915	Up-regulation
CMGC_MAPK_p38_MAPK14_ST	O43526	KCNQ2	Q16539	MAPK14	S476	K482Q	482	Missense	distal	6	no	9.203	9.140	EPSD	TCGA;COSMIC	5.915	Down-regulation
CMGC_MAPK_p38_MAPK14_ST	O43526	KCNQ2	Q16539	MAPK14	S476	S483N	483	Missense	distal	7	no	9.203	8.904	EPSD	TCGA;COSMIC	5.915	Down-regulation
CMGC_MAPK_p38_MAPK14_ST	O43526	KCNQ2	Q16539	MAPK14	S476	E474Q	474	Missense	proximal	-2	no	9.203	8.448	EPSD	TCGA;COSMIC	5.915	Down-regulation
CMGC_MAPK_p38_MAPK14_ST	O43526	KCNQ2	Q16539	MAPK14	S476	V480A	480	Missense	distal	4	no	9.203	9.637	EPSD	TCGA;COSMIC	5.915	Up-regulation
CMGC_MAPK_p38_MAPK14_ST	O43526	KCNQ2	Q16539	MAPK14	S476	D475N	475	Missense	proximal	-1	no	9.203	9.017	EPSD	TCGA;COSMIC	5.915	Down-regulation
CMGC_MAPK_p38_MAPK14_ST	O43526	KCNQ2	Q16539	MAPK14	S485	G487R	487	Missense	proximal	2	no	8.297	8.380	EPSD	TCGA;COSMIC	5.915	Up-regulation
CMGC_MAPK_p38_MAPK14_ST	O43526	KCNQ2	Q16539	MAPK14	S485	K482Q	482	Missense	distal	-3	no	8.297	8.205	EPSD	TCGA;COSMIC	5.915	Down-regulation
CMGC_MAPK_p38_MAPK14_ST	O43526	KCNQ2	Q16539	MAPK14	S485	R489H	489	Missense	distal	4	no	8.297	7.904	EPSD	TCGA;GDSC;CCLE	5.915	Down-regulation
CMGC_MAPK_p38_MAPK14_ST	O43526	KCNQ2	Q16539	MAPK14	S485	S483N	483	Missense	proximal	-2	no	8.297	7.611	EPSD	TCGA;COSMIC	5.915	Down-regulation
CMGC_MAPK_p38_MAPK14_ST	O43526	KCNQ2	Q16539	MAPK14	S485	V480A	480	Missense	distal	-5	no	8.297	7.805	EPSD	TCGA;COSMIC	5.915	Down-regulation
CMGC_MAPK_p38_MAPK14_ST	O43526	KCNQ2	Q16539	MAPK14	S672	P666L	666	Missense	distal	-6	no	12.119	11.506	EPSD	TCGA;COSMIC	5.915	Down-regulation
CMGC_MAPK_p38_MAPK14_ST	O43526	KCNQ2	Q16539	MAPK14	S672	S676R	676	Missense	distal	4	no	12.119	11.402	EPSD	TCGA;ICGC;COSMIC	5.915	Down-regulation
CMGC_MAPK_p38_MAPK14_ST	O43526	KCNQ2	Q16539	MAPK14	S672	R677Q	677	Missense	distal	5	no	12.119	11.770	EPSD	TCGA;COSMIC	5.915	Down-regulation
CMGC_MAPK_p38_MAPK14_ST	O43526	KCNQ2	Q16539	MAPK14	S672	P668Q	668	Missense	distal	-4	no	12.119	12.411	EPSD	TCGA;COSMIC	5.915	Up-regulation
CMGC_MAPK_p38_MAPK14_ST	Q9BUB5	MKNK1	Q16539	MAPK14	S221	L218W	218	Missense	distal	-3	no	9.256	9.142	EPSD	TCGA;COSMIC	5.915	Down-regulation
CMGC_MAPK_p38_MAPK14_ST	Q9BUB5	MKNK1	Q16539	MAPK14	T255	E261K	261	Missense	distal	6	no	10.107	10.101	PhosphoSitePlus;EPSD	TCGA;COSMIC	5.915	Down-regulation
CMGC_MAPK_p38_MAPK14_ST	Q9BUB5	MKNK1	Q16539	MAPK14	T255	S259C	259	Missense	distal	4	no	10.107	8.956	PhosphoSitePlus;EPSD	TCGA;COSMIC	5.915	Down-regulation
CMGC_MAPK_p38_MAPK14_ST	Q9BUB5	MKNK1	Q16539	MAPK14	T255	A260T	260	Missense	distal	5	no	10.107	10.579	PhosphoSitePlus;EPSD	TCGA	5.915	Up-regulation
CMGC_MAPK_p38_MAPK14_ST	Q9BUB5	MKNK1	Q16539	MAPK14	T385	P379L	379	Missense	distal	-6	no	8.427	7.813	EPSD	TCGA;ICGC;COSMIC	5.915	Down-regulation
CMGC_MAPK_p38_MAPK14_ST	Q9BUB5	MKNK1	Q16539	MAPK14	T385	A378T	378	Missense	distal	-7	no	8.427	8.244	EPSD	TCGA;ICGC;COSMIC	5.915	Down-regulation
CMGC_MAPK_p38_MAPK14_ST	Q9BUB5	MKNK1	Q16539	MAPK14	S437	P439S	439	Missense	proximal	2	no	10.642	11.018	EPSD	TCGA;COSMIC	5.915	Up-regulation
CMGC_MAPK_p38_MAPK14_ST	Q9BUB5	MKNK1	Q16539	MAPK14	S437	R443C	443	Missense	distal	6	no	10.642	10.367	EPSD	TCGA;COSMIC	5.915	Down-regulation
CMGC_MAPK_p38_MAPK14_ST	Q9BUB5	MKNK1	Q16539	MAPK14	S437	S437F	437	Missense	central	0	yes	10.642	0.000	EPSD	TCGA;COSMIC	5.915	Loss
CMGC_MAPK_p38_MAPK14_ST	Q9BUB5	MKNK1	Q16539	MAPK14	S460	D458G	458	Missense	proximal	-2	no	9.280	10.031	EPSD	TCGA	5.915	Up-regulation
CMGC_MAPK_p38_MAPK14_ST	Q9Y6Q9	NCOA3	Q16539	MAPK14	T203	R198H	198	Missense	distal	-5	no	6.895	7.438	EPSD	TCGA;ICGC;COSMIC	5.915	Up-regulation
CMGC_MAPK_p38_MAPK14_ST	Q9Y6Q9	NCOA3	Q16539	MAPK14	T203	R198C	198	Missense	distal	-5	no	6.895	7.378	EPSD	TCGA;ICGC;COSMIC	5.915	Up-regulation
CMGC_MAPK_p38_MAPK14_ST	Q9Y6Q9	NCOA3	Q16539	MAPK14	S214	A213G	213	Missense	proximal	-1	no	11.788	11.941	EPSD	TCGA;ICGC;COSMIC	5.915	Up-regulation
CMGC_MAPK_p38_MAPK14_ST	Q9Y6Q9	NCOA3	Q16539	MAPK14	S214	A213V	213	Missense	proximal	-1	no	11.788	11.944	EPSD	TCGA;ICGC;COSMIC	5.915	Up-regulation
CMGC_MAPK_p38_MAPK14_ST	Q9Y6Q9	NCOA3	Q16539	MAPK14	S450	S453F	453	Missense	distal	3	no	9.960	10.068	EPSD	TCGA;ICGC;COSMIC	5.915	Up-regulation
CMGC_MAPK_p38_MAPK14_ST	Q9Y6Q9	NCOA3	Q16539	MAPK14	S450	M448T	448	Missense	proximal	-2	no	9.960	10.052	EPSD	TCGA;ICGC;COSMIC	5.915	Up-regulation
CMGC_MAPK_p38_MAPK14_ST	Q9Y6Q9	NCOA3	Q16539	MAPK14	S450	S450P	450	Missense	central	0	yes	9.960	0.000	EPSD	TCGA;COSMIC	5.915	Loss
CMGC_MAPK_p38_MAPK14_ST	Q9Y6Q9	NCOA3	Q16539	MAPK14	S465	N458T	458	Missense	distal	-7	no	9.402	9.543	EPSD	TCGA;COSMIC	5.915	Up-regulation
CMGC_MAPK_p38_MAPK14_ST	Q9Y6Q9	NCOA3	Q16539	MAPK14	S470	L473F	473	Missense	distal	3	no	8.685	8.719	EPSD	TCGA;COSMIC	5.915	Up-regulation
CMGC_MAPK_p38_MAPK14_ST	Q9Y6Q9	NCOA3	Q16539	MAPK14	S505	P499A	499	Missense	distal	-6	no	11.775	11.839	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	5.915	Up-regulation
CMGC_MAPK_p38_MAPK14_ST	Q9Y6Q9	NCOA3	Q16539	MAPK14	S505	G511D	511	Missense	distal	6	no	11.775	11.633	EPSD;PhosphoSitePlus	TCGA	5.915	Down-regulation
CMGC_MAPK_p38_MAPK14_ST	Q9Y6Q9	NCOA3	Q16539	MAPK14	S543	S542L	542	Missense	proximal	-1	no	13.250	13.528	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	5.915	Up-regulation
CMGC_MAPK_p38_MAPK14_ST	Q9Y6Q9	NCOA3	Q16539	MAPK14	S543	S536F	536	Missense	distal	-7	no	13.250	12.504	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	5.915	Down-regulation
CMGC_MAPK_p38_MAPK14_ST	Q9Y6Q9	NCOA3	Q16539	MAPK14	S543	S539F	539	Missense	distal	-4	no	13.250	13.954	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	5.915	Up-regulation
CMGC_MAPK_p38_MAPK14_ST	Q9Y6Q9	NCOA3	Q16539	MAPK14	S551	P552L	552	Missense	proximal	1	no	9.578	1.527	EPSD	TCGA;ICGC;COSMIC	5.915	Loss
CMGC_MAPK_p38_MAPK14_ST	Q9Y6Q9	NCOA3	Q16539	MAPK14	S635	S628F	628	Missense	distal	-7	no	6.837	6.091	EPSD	TCGA;COSMIC	5.915	Down-regulation
CMGC_MAPK_p38_MAPK14_ST	Q9Y6Q9	NCOA3	Q16539	MAPK14	S640	K647R	647	Missense	distal	7	no	11.405	11.929	EPSD	TCGA;ICGC;COSMIC	5.915	Up-regulation
CMGC_MAPK_p38_MAPK14_ST	Q9Y6Q9	NCOA3	Q16539	MAPK14	S640	S644L	644	Missense	distal	4	no	11.405	10.327	EPSD	TCGA;COSMIC	5.915	Down-regulation
CMGC_MAPK_p38_MAPK14_ST	Q9Y6Q9	NCOA3	Q16539	MAPK14	S655	S662C	662	Missense	distal	7	no	11.209	10.644	EPSD	TCGA;COSMIC	5.915	Down-regulation
CMGC_MAPK_p38_MAPK14_ST	Q9Y6Q9	NCOA3	Q16539	MAPK14	S694	G692E	692	Missense	proximal	-2	no	10.428	11.106	EPSD	TCGA;ICGC;COSMIC	5.915	Up-regulation
CMGC_MAPK_p38_MAPK14_ST	Q9Y6Q9	NCOA3	Q16539	MAPK14	T702	D709Y	709	Missense	distal	7	no	6.084	6.104	EPSD	TCGA;COSMIC	5.915	Up-regulation
CMGC_MAPK_p38_MAPK14_ST	Q9Y6Q9	NCOA3	Q16539	MAPK14	S728	Q724H	724	Missense	distal	-4	no	12.582	12.425	EPSD	TCGA;COSMIC	5.915	Down-regulation
CMGC_MAPK_p38_MAPK14_ST	Q9Y6Q9	NCOA3	Q16539	MAPK14	S728	V721A	721	Missense	distal	-7	no	12.582	13.400	EPSD	TCGA	5.915	Up-regulation
CMGC_MAPK_p38_MAPK14_ST	Q9Y6Q9	NCOA3	Q16539	MAPK14	T770	I774S	774	Missense	distal	4	no	5.321	6.109	EPSD	TCGA;ICGC;COSMIC	5.915	Gain
CMGC_MAPK_p38_MAPK14_ST	Q9Y6Q9	NCOA3	Q16539	MAPK14	S776	I774S	774	Missense	proximal	-2	no	6.180	6.509	EPSD	TCGA;ICGC;COSMIC	5.915	Up-regulation
CMGC_MAPK_p38_MAPK14_ST	Q9Y6Q9	NCOA3	Q16539	MAPK14	S860	S867G	867	Missense	distal	7	no	14.509	14.365	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	5.915	Down-regulation
CMGC_MAPK_p38_MAPK14_ST	Q9Y6Q9	NCOA3	Q16539	MAPK14	S860	R854Q	854	Missense	distal	-6	no	14.509	13.839	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	5.915	Down-regulation
CMGC_MAPK_p38_MAPK14_ST	Q9Y6Q9	NCOA3	Q16539	MAPK14	S866	I873M	873	Missense	distal	7	no	5.708	6.310	EPSD	TCGA;ICGC;COSMIC	5.915	Gain
CMGC_MAPK_p38_MAPK14_ST	Q9Y6Q9	NCOA3	Q16539	MAPK14	S866	P868S	868	Missense	proximal	2	no	5.708	6.085	EPSD	TCGA;ICGC;COSMIC	5.915	Gain
CMGC_MAPK_p38_MAPK14_ST	Q9Y6Q9	NCOA3	Q16539	MAPK14	S867	I873M	873	Missense	distal	6	no	10.395	10.654	PhosphoSitePlus;EPSD	TCGA;ICGC;COSMIC	5.915	Up-regulation
CMGC_MAPK_p38_MAPK14_ST	Q9Y6Q9	NCOA3	Q16539	MAPK14	S867	S867G	867	Missense	central	0	yes	10.395	0.000	PhosphoSitePlus;EPSD	TCGA;ICGC;COSMIC	5.915	Loss
CMGC_MAPK_p38_MAPK14_ST	Q9Y6Q9	NCOA3	Q16539	MAPK14	S867	P868S	868	Missense	proximal	1	no	10.395	3.111	PhosphoSitePlus;EPSD	TCGA;ICGC;COSMIC	5.915	Loss
CMGC_MAPK_p38_MAPK14_ST	Q9Y6Q9	NCOA3	Q16539	MAPK14	S867	P868L	868	Missense	proximal	1	no	10.395	2.344	PhosphoSitePlus;EPSD	TCGA;ICGC;COSMIC	5.915	Loss
CMGC_MAPK_p38_MAPK14_ST	Q9Y6Q9	NCOA3	Q16539	MAPK14	T914	P915S	915	Missense	proximal	1	no	10.161	2.877	EPSD	TCGA;ICGC;COSMIC	5.915	Loss
CMGC_MAPK_p38_MAPK14_ST	Q9Y6Q9	NCOA3	Q16539	MAPK14	T914	R907Q	907	Missense	distal	-7	no	10.161	10.067	EPSD	TCGA;ICGC;COSMIC	5.915	Down-regulation
CMGC_MAPK_p38_MAPK14_ST	Q9Y6Q9	NCOA3	Q16539	MAPK14	S1330	S1337L	1337	Missense	distal	7	no	12.439	12.055	EPSD	TCGA;COSMIC;GDSC;CCLE	5.915	Down-regulation
CMGC_MAPK_p38_MAPK14_ST	P53667	LIMK1	Q16539	MAPK14	S154	S157F	157	Missense	distal	3	no	8.619	8.727	EPSD	TCGA;COSMIC	5.915	Up-regulation
CMGC_MAPK_p38_MAPK14_ST	P53667	LIMK1	Q16539	MAPK14	S210	M209I	209	Missense	proximal	-1	no	8.453	8.307	EPSD	TCGA;COSMIC	5.915	Down-regulation
CMGC_MAPK_p38_MAPK14_ST	P53667	LIMK1	Q16539	MAPK14	S210	G207C	207	Missense	distal	-3	no	8.453	7.707	EPSD	TCGA;COSMIC	5.915	Down-regulation
CMGC_MAPK_p38_MAPK14_ST	P53667	LIMK1	Q16539	MAPK14	S210	S216F	216	Missense	distal	6	no	8.453	8.096	EPSD	TCGA;COSMIC	5.915	Down-regulation
CMGC_MAPK_p38_MAPK14_ST	P53667	LIMK1	Q16539	MAPK14	S210	D212Y	212	Missense	proximal	2	no	8.453	8.613	EPSD	TCGA	5.915	Up-regulation
CMGC_MAPK_p38_MAPK14_ST	P53667	LIMK1	Q16539	MAPK14	S210	C208Y	208	Missense	proximal	-2	no	8.453	9.590	EPSD	TCGA;COSMIC	5.915	Up-regulation
CMGC_MAPK_p38_MAPK14_ST	P53667	LIMK1	Q16539	MAPK14	S210	P206L	206	Missense	distal	-4	no	8.453	8.965	EPSD	TCGA;COSMIC	5.915	Up-regulation
CMGC_MAPK_p38_MAPK14_ST	P53667	LIMK1	Q16539	MAPK14	T229	I231V	231	Missense	proximal	2	no	7.329	7.380	EPSD	TCGA;COSMIC	5.915	Up-regulation
CMGC_MAPK_p38_MAPK14_ST	P53667	LIMK1	Q16539	MAPK14	T229	R232Q	232	Missense	distal	3	no	7.329	7.369	EPSD	TCGA	5.915	Up-regulation
CMGC_MAPK_p38_MAPK14_ST	P53667	LIMK1	Q16539	MAPK14	T270	P276L	276	Missense	distal	6	no	6.217	6.078	EPSD	TCGA;COSMIC;CCLE	5.915	Down-regulation
CMGC_MAPK_p38_MAPK14_ST	P53667	LIMK1	Q16539	MAPK14	S271	P276L	276	Missense	distal	5	no	12.125	11.628	EPSD	TCGA;COSMIC;CCLE	5.915	Down-regulation
CMGC_MAPK_p38_MAPK14_ST	P53667	LIMK1	Q16539	MAPK14	S275	P280S	280	Missense	distal	5	no	10.919	11.369	EPSD	TCGA;COSMIC	5.915	Up-regulation
CMGC_MAPK_p38_MAPK14_ST	P53667	LIMK1	Q16539	MAPK14	S275	P276L	276	Missense	proximal	1	no	10.919	2.868	EPSD	TCGA;COSMIC;CCLE	5.915	Loss
CMGC_MAPK_p38_MAPK14_ST	P53667	LIMK1	Q16539	MAPK14	T279	P280S	280	Missense	proximal	1	no	12.751	5.468	EPSD	TCGA;COSMIC	5.915	Loss
CMGC_MAPK_p38_MAPK14_ST	P53667	LIMK1	Q16539	MAPK14	T279	P276L	276	Missense	distal	-3	no	12.751	11.784	EPSD	TCGA;COSMIC;CCLE	5.915	Down-regulation
CMGC_MAPK_p38_MAPK14_ST	P53667	LIMK1	Q16539	MAPK14	S281	P280S	280	Missense	proximal	-1	no	7.526	7.433	EPSD	TCGA;COSMIC	5.915	Down-regulation
CMGC_MAPK_p38_MAPK14_ST	P53667	LIMK1	Q16539	MAPK14	S281	P276L	276	Missense	distal	-5	no	7.526	7.807	EPSD	TCGA;COSMIC;CCLE	5.915	Up-regulation
CMGC_MAPK_p38_MAPK14_ST	P53667	LIMK1	Q16539	MAPK14	S287	P280S	280	Missense	distal	-7	no	5.939	6.026	EPSD	TCGA;COSMIC	5.915	Up-regulation
CMGC_MAPK_p38_MAPK14_ST	P53667	LIMK1	Q16539	MAPK14	S287	R289Q	289	Missense	proximal	2	no	5.939	5.513	EPSD	TCGA;COSMIC	5.915	Loss
CMGC_MAPK_p38_MAPK14_ST	P53667	LIMK1	Q16539	MAPK14	S287	R289W	289	Missense	proximal	2	no	5.939	5.441	EPSD	TCGA;COSMIC	5.915	Loss
CMGC_MAPK_p38_MAPK14_ST	P53667	LIMK1	Q16539	MAPK14	S298	P303T	303	Missense	distal	5	no	5.735	6.019	EPSD	TCGA;COSMIC	5.915	Gain
CMGC_MAPK_p38_MAPK14_ST	P53667	LIMK1	Q16539	MAPK14	S302	P303T	303	Missense	proximal	1	no	8.829	1.376	EPSD	TCGA;COSMIC	5.915	Loss
CMGC_MAPK_p38_MAPK14_ST	P53667	LIMK1	Q16539	MAPK14	S302	L308P	308	Missense	distal	6	no	8.829	8.968	EPSD	TCGA;COSMIC	5.915	Up-regulation
CMGC_MAPK_p38_MAPK14_ST	P53667	LIMK1	Q16539	MAPK14	S307	L308P	308	Missense	proximal	1	no	4.920	12.970	EPSD	TCGA;COSMIC	5.915	Gain
CMGC_MAPK_p38_MAPK14_ST	P53667	LIMK1	Q16539	MAPK14	S310	R315H	315	Missense	distal	5	no	10.607	9.912	PhosphoSitePlus	TCGA;COSMIC	5.915	Down-regulation
CMGC_MAPK_p38_MAPK14_ST	P53667	LIMK1	Q16539	MAPK14	S310	P311S	311	Missense	proximal	1	no	10.607	3.323	PhosphoSitePlus	TCGA;COSMIC	5.915	Loss
CMGC_MAPK_p38_MAPK14_ST	P53667	LIMK1	Q16539	MAPK14	S310	P303T	303	Missense	distal	-7	no	10.607	10.625	PhosphoSitePlus	TCGA;COSMIC	5.915	Up-regulation
CMGC_MAPK_p38_MAPK14_ST	P53667	LIMK1	Q16539	MAPK14	S310	L308P	308	Missense	proximal	-2	no	10.607	11.987	PhosphoSitePlus	TCGA;COSMIC	5.915	Up-regulation
CMGC_MAPK_p38_MAPK14_ST	P53667	LIMK1	Q16539	MAPK14	S313	R315H	315	Missense	proximal	2	no	5.975	5.592	EPSD	TCGA;COSMIC	5.915	Loss
CMGC_MAPK_p38_MAPK14_ST	P53667	LIMK1	Q16539	MAPK14	S313	P311S	311	Missense	proximal	-2	no	5.975	5.486	EPSD	TCGA;COSMIC	5.915	Loss
CMGC_MAPK_p38_MAPK14_ST	P53667	LIMK1	Q16539	MAPK14	S313	R320C	320	Missense	distal	7	no	5.975	5.375	EPSD	TCGA;COSMIC	5.915	Loss
CMGC_MAPK_p38_MAPK14_ST	P53667	LIMK1	Q16539	MAPK14	S313	L308P	308	Missense	distal	-5	no	5.975	5.693	EPSD	TCGA;COSMIC	5.915	Loss
CMGC_MAPK_p38_MAPK14_ST	P53667	LIMK1	Q16539	MAPK14	S534	L539M	539	Missense	distal	5	no	5.711	6.179	EPSD	TCGA;COSMIC	5.915	Gain
CMGC_MAPK_p38_MAPK14_ST	Q15672	TWIST1	Q16539	MAPK14	S99	G97S	97	Missense	proximal	-2	no	12.310	12.760	EPSD	TCGA;ICGC;COSMIC	5.915	Up-regulation
CMGC_MAPK_p38_MAPK14_ST	P49137	MAPKAPK2	Q16539	MAPK14	T25	T25P	25	Missense	central	0	yes	10.957	0.000	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	5.915	Loss
CMGC_MAPK_p38_MAPK14_ST	P49137	MAPKAPK2	Q16539	MAPK14	S272	R278C	278	Missense	distal	6	no	10.608	10.334	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	5.915	Down-regulation
CMGC_MAPK_p38_MAPK14_ST	P49137	MAPKAPK2	Q16539	MAPK14	S272	P273L	273	Missense	proximal	1	no	10.608	2.558	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	5.915	Loss
CMGC_MAPK_p38_MAPK14_ST	P49137	MAPKAPK2	Q16539	MAPK14	T334	S339N	339	Missense	distal	5	no	11.967	11.631	EPSD;PhosphoSitePlus	TCGA;ICGC	5.915	Down-regulation
CMGC_MAPK_p38_MAPK14_ST	P19525	EIF2AK2	Q16539	MAPK14	S83	T88A	88	Missense	distal	5	no	7.056	6.584	EPSD	TCGA;ICGC;COSMIC	5.915	Down-regulation
CMGC_MAPK_p38_MAPK14_ST	P19525	EIF2AK2	Q16539	MAPK14	S83	K79N	79	Missense	distal	-4	no	7.056	7.203	EPSD	TCGA;ICGC;COSMIC	5.915	Up-regulation
CMGC_MAPK_p38_MAPK14_ST	P19525	EIF2AK2	Q16539	MAPK14	S83	K77T	77	Missense	distal	-6	no	7.056	7.369	EPSD	TCGA;ICGC	5.915	Up-regulation
CMGC_MAPK_p38_MAPK14_ST	P19525	EIF2AK2	Q16539	MAPK14	T90	T88A	88	Missense	proximal	-2	no	6.329	6.386	EPSD	TCGA;ICGC;COSMIC	5.915	Up-regulation
CMGC_MAPK_p38_MAPK14_ST	P19525	EIF2AK2	Q16539	MAPK14	T90	S92Y	92	Missense	proximal	2	no	6.329	6.003	EPSD	TCGA;ICGC;COSMIC	5.915	Down-regulation
CMGC_MAPK_p38_MAPK14_ST	P19525	EIF2AK2	Q16539	MAPK14	S181	S181F	181	Missense	central	0	yes	6.762	0.000	EPSD	TCGA;ICGC;COSMIC	5.915	Loss
CMGC_MAPK_p38_MAPK14_ST	P19525	EIF2AK2	Q16539	MAPK14	S542	L536F	536	Missense	distal	-6	no	10.177	9.633	EPSD	TCGA;ICGC;COSMIC	5.915	Down-regulation
CMGC_MAPK_p38_MAPK14_ST	P19525	EIF2AK2	Q16539	MAPK14	S542	E544D	544	Missense	proximal	2	no	10.177	9.726	EPSD	TCGA;ICGC	5.915	Down-regulation
CMGC_MAPK_p38_MAPK14_ST	O75582	RPS6KA5	Q16539	MAPK14	S212	A210V	210	Missense	proximal	-2	no	6.531	6.116	EPSD	TCGA;ICGC;COSMIC	5.915	Down-regulation
CMGC_MAPK_p38_MAPK14_ST	O75582	RPS6KA5	Q16539	MAPK14	S212	E208Q	208	Missense	distal	-4	no	6.531	7.209	EPSD	TCGA;ICGC;COSMIC	5.915	Up-regulation
CMGC_MAPK_p38_MAPK14_ST	O75582	RPS6KA5	Q16539	MAPK14	S253	S253Y	253	Missense	central	0	yes	11.620	0.000	EPSD	TCGA;ICGC;COSMIC	5.915	Loss
CMGC_MAPK_p38_MAPK14_ST	O75582	RPS6KA5	Q16539	MAPK14	S253	D258N	258	Missense	distal	5	no	11.620	11.829	EPSD	TCGA;ICGC;COSMIC	5.915	Up-regulation
CMGC_MAPK_p38_MAPK14_ST	O75582	RPS6KA5	Q16539	MAPK14	T353	T353A	353	Missense	central	0	yes	6.747	0.000	EPSD	TCGA;COSMIC	5.915	Loss
CMGC_MAPK_p38_MAPK14_ST	O75582	RPS6KA5	Q16539	MAPK14	S360	T353A	353	Missense	distal	-7	no	11.097	11.279	PhosphoSitePlus;EPSD	TCGA;COSMIC	5.915	Up-regulation
CMGC_MAPK_p38_MAPK14_ST	O75582	RPS6KA5	Q16539	MAPK14	S376	Y375F	375	Missense	proximal	-1	no	5.976	6.218	EPSD	TCGA;ICGC;COSMIC	5.915	Up-regulation
CMGC_MAPK_p38_MAPK14_ST	O75582	RPS6KA5	Q16539	MAPK14	S376	S376C	376	Missense	central	0	yes	5.976	0.000	EPSD	TCGA;ICGC	5.915	Loss
CMGC_MAPK_p38_MAPK14_ST	O75582	RPS6KA5	Q16539	MAPK14	S376	L383I	383	Missense	distal	7	no	5.976	5.628	EPSD	TCGA;ICGC	5.915	Loss
CMGC_MAPK_p38_MAPK14_ST	O75582	RPS6KA5	Q16539	MAPK14	S436	G433R	433	Missense	distal	-3	no	5.247	6.697	EPSD	TCGA	5.915	Gain
CMGC_MAPK_p38_MAPK14_ST	O75582	RPS6KA5	Q16539	MAPK14	T581	K580N	580	Missense	proximal	-1	no	10.790	10.888	EPSD;PhosphoSitePlus	TCGA;COSMIC	5.915	Up-regulation
CMGC_MAPK_p38_MAPK14_ST	O75582	RPS6KA5	Q16539	MAPK14	T581	H587Q	587	Missense	distal	6	no	10.790	10.909	EPSD;PhosphoSitePlus	TCGA;ICGC	5.915	Up-regulation
CMGC_MAPK_p38_MAPK14_ST	O75582	RPS6KA5	Q16539	MAPK14	T700	P701L	701	Missense	proximal	1	no	11.163	3.112	EPSD	TCGA;COSMIC	5.915	Loss
CMGC_MAPK_p38_MAPK14_ST	O75582	RPS6KA5	Q16539	MAPK14	T700	I703S	703	Missense	distal	3	no	11.163	11.067	EPSD	TCGA;ICGC;COSMIC	5.915	Down-regulation
CMGC_MAPK_p38_MAPK14_ST	O75582	RPS6KA5	Q16539	MAPK14	S750	T751S	751	Missense	proximal	1	no	6.200	6.369	EPSD	TCGA;COSMIC	5.915	Up-regulation
CMGC_MAPK_p38_MAPK14_ST	O75582	RPS6KA5	Q16539	MAPK14	S750	S750I	750	Missense	central	0	yes	6.200	0.000	EPSD	TCGA;COSMIC	5.915	Loss
CMGC_MAPK_p38_MAPK14_ST	O75582	RPS6KA5	Q16539	MAPK14	S768	H769Y	769	Missense	proximal	1	no	0.585	6.962	EPSD	TCGA;COSMIC	5.915	Gain
CMGC_MAPK_p38_MAPK14_ST	O75582	RPS6KA5	Q16539	MAPK14	T775	H769Y	769	Missense	distal	-6	no	7.480	7.783	EPSD	TCGA;COSMIC	5.915	Up-regulation
CMGC_MAPK_p38_MAPK14_ST	O75582	RPS6KA5	Q16539	MAPK14	T775	P782H	782	Missense	distal	7	no	7.480	7.202	EPSD	TCGA	5.915	Down-regulation
CMGC_MAPK_p38_MAPK14_ST	O75582	RPS6KA5	Q16539	MAPK14	T775	S768F	768	Missense	distal	-7	no	7.480	6.734	EPSD	TCGA	5.915	Down-regulation
CMGC_MAPK_p38_MAPK14_ST	P21397	MAOA	Q16539	MAPK14	T54	R47K	47	Missense	distal	-7	no	5.800	6.065	EPSD	TCGA;ICGC;COSMIC	5.915	Gain
CMGC_MAPK_p38_MAPK14_ST	P21397	MAOA	Q16539	MAPK14	S209	R206W	206	Missense	distal	-3	no	5.949	3.592	PhosphoSitePlus	TCGA;COSMIC	5.915	Loss
CMGC_MAPK_p38_MAPK14_ST	P43403	ZAP70	Q16539	MAPK14	S88	G93E	93	Missense	distal	5	no	6.932	7.149	EPSD	TCGA	5.915	Up-regulation
CMGC_MAPK_p38_MAPK14_ST	P43403	ZAP70	Q16539	MAPK14	S88	P91H	91	Missense	distal	3	no	6.932	6.991	EPSD	TCGA;ICGC;COSMIC	5.915	Up-regulation
CMGC_MAPK_p38_MAPK14_ST	P43403	ZAP70	Q16539	MAPK14	S88	F86L	86	Missense	proximal	-2	no	6.932	6.764	EPSD	TCGA;ICGC;COSMIC	5.915	Down-regulation
CMGC_MAPK_p38_MAPK14_ST	P43403	ZAP70	Q16539	MAPK14	S167	R160W	160	Missense	distal	-7	no	6.251	5.511	EPSD	TCGA;ICGC;COSMIC	5.915	Loss
CMGC_MAPK_p38_MAPK14_ST	P43403	ZAP70	Q16539	MAPK14	S167	E174V	174	Missense	distal	7	no	6.251	5.947	EPSD	TCGA;ICGC;COSMIC	5.915	Down-regulation
CMGC_MAPK_p38_MAPK14_ST	P43403	ZAP70	Q16539	MAPK14	S258	E252V	252	Missense	distal	-6	no	7.695	6.835	EPSD	TCGA;ICGC;COSMIC	5.915	Down-regulation
CMGC_MAPK_p38_MAPK14_ST	P43403	ZAP70	Q16539	MAPK14	S258	A262T	262	Missense	distal	4	no	7.695	7.740	EPSD	TCGA;ICGC;CCLE	5.915	Up-regulation
CMGC_MAPK_p38_MAPK14_ST	P43403	ZAP70	Q16539	MAPK14	T278	H279P	279	Missense	proximal	1	no	-1.361	12.293	EPSD	TCGA	5.915	Gain
CMGC_MAPK_p38_MAPK14_ST	P43403	ZAP70	Q16539	MAPK14	S301	D303N	303	Missense	proximal	2	no	14.258	14.488	EPSD	TCGA;ICGC;COSMIC	5.915	Up-regulation
CMGC_MAPK_p38_MAPK14_ST	P43403	ZAP70	Q16539	MAPK14	S301	R306W	306	Missense	distal	5	no	14.258	13.364	EPSD	TCGA;ICGC;COSMIC	5.915	Down-regulation
CMGC_MAPK_p38_MAPK14_ST	P43403	ZAP70	Q16539	MAPK14	T312	V314M	314	Missense	proximal	2	no	6.237	6.410	EPSD	TCGA;ICGC;COSMIC	5.915	Up-regulation
CMGC_MAPK_p38_MAPK14_ST	P43403	ZAP70	Q16539	MAPK14	T312	R306W	306	Missense	distal	-6	no	6.237	4.919	EPSD	TCGA;ICGC;COSMIC	5.915	Loss
CMGC_MAPK_p38_MAPK14_ST	P43403	ZAP70	Q16539	MAPK14	S317	E324K	324	Missense	distal	7	no	10.927	10.220	EPSD	TCGA;ICGC;COSMIC	5.915	Down-regulation
CMGC_MAPK_p38_MAPK14_ST	P43403	ZAP70	Q16539	MAPK14	S317	V314M	314	Missense	distal	-3	no	10.927	11.416	EPSD	TCGA;ICGC;COSMIC	5.915	Up-regulation
CMGC_MAPK_p38_MAPK14_ST	P43403	ZAP70	Q16539	MAPK14	S317	D321N	321	Missense	distal	4	no	10.927	11.580	EPSD	TCGA;ICGC;COSMIC	5.915	Up-regulation
CMGC_MAPK_p38_MAPK14_ST	P43403	ZAP70	Q16539	MAPK14	S491	R496H	496	Missense	distal	5	no	6.117	5.422	EPSD	TCGA;ICGC;COSMIC	5.915	Loss
CMGC_MAPK_p38_MAPK14_ST	P43403	ZAP70	Q16539	MAPK14	S491	Y492C	492	Missense	proximal	1	no	6.117	1.667	EPSD	TCGA;ICGC;COSMIC	5.915	Loss
CMGC_MAPK_p38_MAPK14_ST	P43403	ZAP70	Q16539	MAPK14	S491	A485S	485	Missense	distal	-6	no	6.117	6.659	EPSD	TCGA;ICGC;COSMIC	5.915	Up-regulation
CMGC_MAPK_p38_MAPK14_ST	P43403	ZAP70	Q16539	MAPK14	T494	R496H	496	Missense	proximal	2	no	6.181	5.798	EPSD	TCGA;ICGC;COSMIC	5.915	Loss
CMGC_MAPK_p38_MAPK14_ST	P43403	ZAP70	Q16539	MAPK14	T494	Y492C	492	Missense	proximal	-2	no	6.181	5.043	EPSD	TCGA;ICGC;COSMIC	5.915	Loss
CMGC_MAPK_p38_MAPK14_ST	P43403	ZAP70	Q16539	MAPK14	S520	R519H	519	Missense	proximal	-1	no	5.897	6.052	EPSD	TCGA;ICGC;COSMIC	5.915	Gain
CMGC_MAPK_p38_MAPK14_ST	P27816	MAP4	Q16539	MAPK14	T76	S78F	78	Missense	proximal	2	no	11.189	10.523	EPSD	TCGA	5.915	Down-regulation
CMGC_MAPK_p38_MAPK14_ST	P27816	MAP4	Q16539	MAPK14	S156	A160S	160	Missense	distal	4	no	5.908	6.214	EPSD	TCGA;ICGC;COSMIC	5.915	Gain
CMGC_MAPK_p38_MAPK14_ST	P27816	MAP4	Q16539	MAPK14	S205	V209I	209	Missense	distal	4	no	10.439	10.390	EPSD	TCGA;ICGC;COSMIC	5.915	Down-regulation
CMGC_MAPK_p38_MAPK14_ST	P27816	MAP4	Q16539	MAPK14	S358	D363G	363	Missense	distal	5	no	9.205	9.493	EPSD	TCGA;ICGC	5.915	Up-regulation
CMGC_MAPK_p38_MAPK14_ST	P27816	MAP4	Q16539	MAPK14	S384	K377N	377	Missense	distal	-7	no	11.088	10.780	EPSD	TCGA;COSMIC	5.915	Down-regulation
CMGC_MAPK_p38_MAPK14_ST	P27816	MAP4	Q16539	MAPK14	S384	M388V	388	Missense	distal	4	no	11.088	10.672	EPSD	TCGA;ICGC;COSMIC	5.915	Down-regulation
CMGC_MAPK_p38_MAPK14_ST	P27816	MAP4	Q16539	MAPK14	S507	M514I	514	Missense	distal	7	no	11.292	10.690	EPSD	TCGA;ICGC;COSMIC	5.915	Down-regulation
CMGC_MAPK_p38_MAPK14_ST	P27816	MAP4	Q16539	MAPK14	S507	G501C	501	Missense	distal	-6	no	11.292	10.480	EPSD	TCGA;ICGC;COSMIC	5.915	Down-regulation
CMGC_MAPK_p38_MAPK14_ST	P27816	MAP4	Q16539	MAPK14	S510	M514I	514	Missense	distal	4	no	6.715	6.250	EPSD	TCGA;ICGC;COSMIC	5.915	Down-regulation
CMGC_MAPK_p38_MAPK14_ST	P27816	MAP4	Q16539	MAPK14	T521	D519Y	519	Missense	proximal	-2	no	11.676	12.880	EPSD	TCGA;ICGC;COSMIC	5.915	Up-regulation
CMGC_MAPK_p38_MAPK14_ST	P27816	MAP4	Q16539	MAPK14	T521	M514I	514	Missense	distal	-7	no	11.676	11.271	EPSD	TCGA;ICGC;COSMIC	5.915	Down-regulation
CMGC_MAPK_p38_MAPK14_ST	P27816	MAP4	Q16539	MAPK14	T571	D575G	575	Missense	distal	4	no	9.086	10.024	EPSD	TCGA;ICGC;COSMIC	5.915	Up-regulation
CMGC_MAPK_p38_MAPK14_ST	P27816	MAP4	Q16539	MAPK14	S580	D575G	575	Missense	distal	-5	no	6.546	6.304	EPSD	TCGA;ICGC;COSMIC	5.915	Down-regulation
CMGC_MAPK_p38_MAPK14_ST	P27816	MAP4	Q16539	MAPK14	T585	D591Y	591	Missense	distal	6	no	11.561	11.600	EPSD	TCGA;ICGC;COSMIC	5.915	Up-regulation
CMGC_MAPK_p38_MAPK14_ST	P27816	MAP4	Q16539	MAPK14	S624	E626K	626	Missense	proximal	2	no	10.181	9.867	EPSD	TCGA;ICGC	5.915	Down-regulation
CMGC_MAPK_p38_MAPK14_ST	P27816	MAP4	Q16539	MAPK14	S659	P653A	653	Missense	distal	-6	no	6.485	6.549	EPSD	TCGA;ICGC;COSMIC	5.915	Up-regulation
CMGC_MAPK_p38_MAPK14_ST	P27816	MAP4	Q16539	MAPK14	S659	E664D	664	Missense	distal	5	no	6.485	5.979	EPSD	TCGA;ICGC	5.915	Down-regulation
CMGC_MAPK_p38_MAPK14_ST	P27816	MAP4	Q16539	MAPK14	S662	E664D	664	Missense	proximal	2	no	8.246	7.795	EPSD	TCGA;ICGC	5.915	Down-regulation
CMGC_MAPK_p38_MAPK14_ST	P27816	MAP4	Q16539	MAPK14	S666	E664D	664	Missense	proximal	-2	no	6.032	4.603	EPSD	TCGA;ICGC	5.915	Loss
CMGC_MAPK_p38_MAPK14_ST	P27816	MAP4	Q16539	MAPK14	T687	P694S	694	Missense	distal	7	no	9.097	9.319	EPSD	TCGA;ICGC;COSMIC	5.915	Up-regulation
CMGC_MAPK_p38_MAPK14_ST	P27816	MAP4	Q16539	MAPK14	S696	P694S	694	Missense	proximal	-2	no	13.579	13.090	PhosphoSitePlus;EPSD	TCGA;ICGC;COSMIC	5.915	Down-regulation
CMGC_MAPK_p38_MAPK14_ST	P27816	MAP4	Q16539	MAPK14	S787	K790M	790	Missense	distal	3	no	11.725	11.719	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	5.915	Down-regulation
CMGC_MAPK_p38_MAPK14_ST	P27816	MAP4	Q16539	MAPK14	T892	R897W	897	Missense	distal	5	no	8.461	7.567	EPSD	TCGA;ICGC;COSMIC	5.915	Down-regulation
CMGC_MAPK_p38_MAPK14_ST	P27816	MAP4	Q16539	MAPK14	T901	R897W	897	Missense	distal	-4	no	8.464	9.093	EPSD	TCGA;ICGC;COSMIC	5.915	Up-regulation
CMGC_MAPK_p38_MAPK14_ST	P27816	MAP4	Q16539	MAPK14	T901	P902H	902	Missense	proximal	1	no	8.464	-5.190	EPSD	TCGA;ICGC	5.915	Loss
CMGC_MAPK_p38_MAPK14_ST	P27816	MAP4	Q16539	MAPK14	T917	L920H	920	Missense	distal	3	no	13.292	13.317	EPSD	TCGA;ICGC;COSMIC	5.915	Up-regulation
CMGC_MAPK_p38_MAPK14_ST	P27816	MAP4	Q16539	MAPK14	S1145	Q1141H	1141	Missense	distal	-4	no	7.107	6.950	EPSD	TCGA;ICGC;COSMIC	5.915	Down-regulation
CMGC_MAPK_p38_MAPK14_ST	Q9H211	CDT1	Q16539	MAPK14	S93	K100N	100	Missense	distal	7	no	10.051	10.242	EPSD	TCGA;ICGC;COSMIC	5.915	Up-regulation
CMGC_MAPK_p38_MAPK14_ST	Q9H211	CDT1	Q16539	MAPK14	S93	P94L	94	Missense	proximal	1	no	10.051	2.001	EPSD	TCGA;ICGC;COSMIC	5.915	Loss
CMGC_MAPK_p38_MAPK14_ST	Q9H211	CDT1	Q16539	MAPK14	T102	K100N	100	Missense	proximal	-2	no	9.473	9.590	EPSD	TCGA;ICGC;COSMIC	5.915	Up-regulation
CMGC_MAPK_p38_MAPK14_ST	Q9H211	CDT1	Q16539	MAPK14	T102	A104T	104	Missense	proximal	2	no	9.473	9.502	EPSD	TCGA;ICGC;COSMIC	5.915	Up-regulation
CMGC_MAPK_p38_MAPK14_ST	Q9H211	CDT1	Q16539	MAPK14	T102	A105T	105	Missense	distal	3	no	9.473	9.472	EPSD	TCGA;ICGC;COSMIC	5.915	Down-regulation
CMGC_MAPK_p38_MAPK14_ST	Q9H211	CDT1	Q16539	MAPK14	T152	E156D	156	Missense	distal	4	no	11.586	9.917	EPSD	TCGA;ICGC	5.915	Down-regulation
CMGC_MAPK_p38_MAPK14_ST	Q9H211	CDT1	Q16539	MAPK14	T152	E156K	156	Missense	distal	4	no	11.586	11.121	EPSD	TCGA;ICGC;COSMIC	5.915	Down-regulation
CMGC_MAPK_p38_MAPK14_ST	Q9H211	CDT1	Q16539	MAPK14	T152	G157D	157	Missense	distal	5	no	11.586	11.297	EPSD	TCGA;ICGC	5.915	Down-regulation
CMGC_MAPK_p38_MAPK14_ST	Q9H211	CDT1	Q16539	MAPK14	T213	P214H	214	Missense	proximal	1	no	9.181	-4.473	EPSD	TCGA;ICGC;COSMIC	5.915	Loss
CMGC_MAPK_p38_MAPK14_ST	Q9H211	CDT1	Q16539	MAPK14	T213	T213M	213	Missense	central	0	yes	9.181	0.000	EPSD	TCGA;ICGC;COSMIC	5.915	Loss
CMGC_MAPK_p38_MAPK14_ST	Q9H211	CDT1	Q16539	MAPK14	T213	E212K	212	Missense	proximal	-1	no	9.181	9.242	EPSD	TCGA;ICGC;COSMIC;GDSC;CCLE	5.915	Up-regulation
CMGC_MAPK_p38_MAPK14_ST	Q9H211	CDT1	Q16539	MAPK14	T213	N209S	209	Missense	distal	-4	no	9.181	9.108	EPSD	TCGA;ICGC;COSMIC	5.915	Down-regulation
CMGC_MAPK_p38_MAPK14_ST	Q9H211	CDT1	Q16539	MAPK14	S318	A312S	312	Missense	distal	-6	no	11.534	12.077	EPSD	TCGA;ICGC	5.915	Up-regulation
CMGC_MAPK_p38_MAPK14_ST	Q9H211	CDT1	Q16539	MAPK14	S372	R366Q	366	Missense	distal	-6	no	11.415	10.745	EPSD	TCGA;ICGC;COSMIC	5.915	Down-regulation
CMGC_MAPK_p38_MAPK14_ST	Q9H211	CDT1	Q16539	MAPK14	S372	P373L	373	Missense	proximal	1	no	11.415	3.364	EPSD	TCGA;ICGC	5.915	Loss
CMGC_MAPK_p38_MAPK14_ST	Q9H211	CDT1	Q16539	MAPK14	S386	S386F	386	Missense	central	0	yes	6.324	0.000	EPSD	TCGA;ICGC;COSMIC	5.915	Loss
CMGC_MAPK_p38_MAPK14_ST	Q9H211	CDT1	Q16539	MAPK14	S386	R385H	385	Missense	proximal	-1	no	6.324	6.480	EPSD	TCGA;ICGC;COSMIC	5.915	Up-regulation
CMGC_MAPK_p38_MAPK14_ST	Q9H211	CDT1	Q16539	MAPK14	S391	S386F	386	Missense	distal	-5	no	11.410	12.195	PhosphoSitePlus;EPSD	TCGA;ICGC;COSMIC	5.915	Up-regulation
CMGC_MAPK_p38_MAPK14_ST	Q9H211	CDT1	Q16539	MAPK14	S391	R385H	385	Missense	distal	-6	no	11.410	10.447	PhosphoSitePlus;EPSD	TCGA;ICGC;COSMIC	5.915	Down-regulation
CMGC_MAPK_p38_MAPK14_ST	Q9H211	CDT1	Q16539	MAPK14	T402	P404A	404	Missense	proximal	2	no	11.215	11.328	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	5.915	Up-regulation
CMGC_MAPK_p38_MAPK14_ST	Q9H211	CDT1	Q16539	MAPK14	T402	A409T	409	Missense	distal	7	no	11.215	10.872	EPSD;PhosphoSitePlus	TCGA;ICGC	5.915	Down-regulation
CMGC_MAPK_p38_MAPK14_ST	Q9H211	CDT1	Q16539	MAPK14	T406	P404A	404	Missense	proximal	-2	no	11.078	10.415	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	5.915	Down-regulation
CMGC_MAPK_p38_MAPK14_ST	Q9H211	CDT1	Q16539	MAPK14	T406	A409T	409	Missense	distal	3	no	11.078	11.077	EPSD;PhosphoSitePlus	TCGA;ICGC	5.915	Down-regulation
CMGC_MAPK_p38_MAPK14_ST	Q9H211	CDT1	Q16539	MAPK14	S411	P404A	404	Missense	distal	-7	no	10.413	10.614	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	5.915	Up-regulation
CMGC_MAPK_p38_MAPK14_ST	Q9H211	CDT1	Q16539	MAPK14	S411	A409T	409	Missense	proximal	-2	no	10.413	10.356	EPSD;PhosphoSitePlus	TCGA;ICGC	5.915	Down-regulation
CMGC_MAPK_p38_MAPK14_ST	Q00613	HSF1	Q16539	MAPK14	S123	I130V	130	Missense	distal	7	no	5.701	6.347	EPSD	TCGA;COSMIC	5.915	Gain
CMGC_MAPK_p38_MAPK14_ST	Q00613	HSF1	Q16539	MAPK14	S123	L125M	125	Missense	proximal	2	no	5.701	5.936	EPSD	TCGA;COSMIC	5.915	Gain
CMGC_MAPK_p38_MAPK14_ST	Q00613	HSF1	Q16539	MAPK14	S244	S250C	250	Missense	distal	6	no	16.698	16.424	EPSD	TCGA;COSMIC	5.915	Down-regulation
CMGC_MAPK_p38_MAPK14_ST	Q00613	HSF1	Q16539	MAPK14	S275	P276L	276	Missense	proximal	1	no	14.111	6.061	EPSD	TCGA;COSMIC	5.915	Down-regulation
CMGC_MAPK_p38_MAPK14_ST	Q00613	HSF1	Q16539	MAPK14	S275	M277V	277	Missense	proximal	2	no	14.111	13.938	EPSD	TCGA;COSMIC	5.915	Down-regulation
CMGC_MAPK_p38_MAPK14_ST	Q00613	HSF1	Q16539	MAPK14	S279	P276L	276	Missense	distal	-3	no	10.463	9.495	EPSD	TCGA;COSMIC	5.915	Down-regulation
CMGC_MAPK_p38_MAPK14_ST	Q00613	HSF1	Q16539	MAPK14	S279	E286K	286	Missense	distal	7	no	10.463	9.756	EPSD	TCGA;COSMIC	5.915	Down-regulation
CMGC_MAPK_p38_MAPK14_ST	Q00613	HSF1	Q16539	MAPK14	S279	M277V	277	Missense	proximal	-2	no	10.463	10.197	EPSD	TCGA;COSMIC	5.915	Down-regulation
CMGC_MAPK_p38_MAPK14_ST	Q00613	HSF1	Q16539	MAPK14	S292	R296C	296	Missense	distal	4	no	11.025	10.590	EPSD	TCGA;COSMIC	5.915	Down-regulation
CMGC_MAPK_p38_MAPK14_ST	Q00613	HSF1	Q16539	MAPK14	S292	P288L	288	Missense	distal	-4	no	11.025	11.537	EPSD	TCGA;COSMIC	5.915	Up-regulation
CMGC_MAPK_p38_MAPK14_ST	Q00613	HSF1	Q16539	MAPK14	S292	E286K	286	Missense	distal	-6	no	11.025	10.610	EPSD	TCGA;COSMIC	5.915	Down-regulation
CMGC_MAPK_p38_MAPK14_ST	Q00613	HSF1	Q16539	MAPK14	S303	E300Q	300	Missense	distal	-3	no	12.833	12.349	EPSD;PhosphoSitePlus	TCGA	5.915	Down-regulation
CMGC_MAPK_p38_MAPK14_ST	Q00613	HSF1	Q16539	MAPK14	S303	R296C	296	Missense	distal	-7	no	12.833	12.441	EPSD;PhosphoSitePlus	TCGA;COSMIC	5.915	Down-regulation
CMGC_MAPK_p38_MAPK14_ST	Q00613	HSF1	Q16539	MAPK14	S307	E300Q	300	Missense	distal	-7	no	11.613	11.200	PhosphoSitePlus;EPSD	TCGA	5.915	Down-regulation
CMGC_MAPK_p38_MAPK14_ST	Q00613	HSF1	Q16539	MAPK14	S314	R317H	317	Missense	distal	3	no	11.567	11.638	EPSD	TCGA;COSMIC	5.915	Up-regulation
CMGC_MAPK_p38_MAPK14_ST	Q00613	HSF1	Q16539	MAPK14	S314	S320F	320	Missense	distal	6	no	11.567	11.210	EPSD	TCGA;COSMIC	5.915	Down-regulation
CMGC_MAPK_p38_MAPK14_ST	Q00613	HSF1	Q16539	MAPK14	S326	D332Y	332	Missense	distal	6	no	11.459	11.497	EPSD;PhosphoSitePlus	TCGA;COSMIC	5.915	Up-regulation
CMGC_MAPK_p38_MAPK14_ST	Q00613	HSF1	Q16539	MAPK14	S326	T323I	323	Missense	distal	-3	no	11.459	9.705	EPSD;PhosphoSitePlus	TCGA;COSMIC	5.915	Down-regulation
CMGC_MAPK_p38_MAPK14_ST	Q00613	HSF1	Q16539	MAPK14	S326	S320F	320	Missense	distal	-6	no	11.459	9.694	EPSD;PhosphoSitePlus	TCGA;COSMIC	5.915	Down-regulation
CMGC_MAPK_p38_MAPK14_ST	Q00613	HSF1	Q16539	MAPK14	S326	A329T	329	Missense	distal	3	no	11.459	11.458	EPSD;PhosphoSitePlus	TCGA;COSMIC	5.915	Down-regulation
CMGC_MAPK_p38_MAPK14_ST	Q00613	HSF1	Q16539	MAPK14	S326	S333F	333	Missense	distal	7	no	11.459	10.589	EPSD;PhosphoSitePlus	TCGA;COSMIC	5.915	Down-regulation
CMGC_MAPK_p38_MAPK14_ST	Q00613	HSF1	Q16539	MAPK14	S326	P327L	327	Missense	proximal	1	no	11.459	3.408	EPSD;PhosphoSitePlus	TCGA	5.915	Loss
CMGC_MAPK_p38_MAPK14_ST	Q00613	HSF1	Q16539	MAPK14	S363	P364S	364	Missense	proximal	1	no	14.180	6.896	EPSD	TCGA;COSMIC	5.915	Down-regulation
CMGC_MAPK_p38_MAPK14_ST	Q00613	HSF1	Q16539	MAPK14	T369	P364S	364	Missense	distal	-5	no	12.214	11.766	EPSD	TCGA;COSMIC	5.915	Down-regulation
CMGC_MAPK_p38_MAPK14_ST	Q00613	HSF1	Q16539	MAPK14	S419	P420L	420	Missense	proximal	1	no	11.046	2.995	EPSD	TCGA;ICGC;COSMIC	5.915	Loss
CMGC_MAPK_p38_MAPK14_ST	Q00613	HSF1	Q16539	MAPK14	S419	P425S	425	Missense	distal	6	no	11.046	11.034	EPSD	TCGA;ICGC;COSMIC	5.915	Down-regulation
CMGC_MAPK_p38_MAPK14_ST	Q00613	HSF1	Q16539	MAPK14	S444	E441K	441	Missense	distal	-3	no	11.173	10.780	EPSD	TCGA;COSMIC	5.915	Down-regulation
CMGC_MAPK_p38_MAPK14_ST	Q00613	HSF1	Q16539	MAPK14	S458	E453K	453	Missense	distal	-5	no	10.291	10.625	EPSD	TCGA;COSMIC	5.915	Up-regulation
CMGC_MAPK_p38_MAPK14_ST	P17844	DDX5	Q16539	MAPK14	T446	V453E	453	Missense	distal	7	no	9.682	9.986	PhosphoSitePlus;EPSD	TCGA;ICGC;COSMIC	5.915	Up-regulation
CMGC_MAPK_p38_MAPK14_ST	P17844	DDX5	Q16539	MAPK14	S519	D525H	525	Missense	distal	6	no	6.564	6.476	EPSD	TCGA;ICGC;COSMIC	5.915	Down-regulation
CMGC_MAPK_p38_MAPK14_ST	P17844	DDX5	Q16539	MAPK14	S519	F526C	526	Missense	distal	7	no	6.564	6.868	EPSD	TCGA;ICGC;COSMIC	5.915	Up-regulation
CMGC_MAPK_p38_MAPK14_ST	Q9UK80	USP21	Q16539	MAPK14	S93	P96T	96	Missense	distal	3	no	11.055	11.028	EPSD	TCGA;ICGC;COSMIC	5.915	Down-regulation
CMGC_MAPK_p38_MAPK14_ST	Q9UK80	USP21	Q16539	MAPK14	S93	G87R	87	Missense	distal	-6	no	11.055	11.429	EPSD	TCGA;ICGC;COSMIC	5.915	Up-regulation
CMGC_MAPK_p38_MAPK14_ST	Q9UK80	USP21	Q16539	MAPK14	S93	H86Y	86	Missense	distal	-7	no	11.055	10.958	EPSD	TCGA;ICGC;COSMIC	5.915	Down-regulation
CMGC_MAPK_p38_MAPK14_ST	Q9UK80	USP21	Q16539	MAPK14	S93	H86R	86	Missense	distal	-7	no	11.055	11.349	EPSD	TCGA;ICGC;COSMIC	5.915	Up-regulation
CMGC_MAPK_p38_MAPK14_ST	Q9UK80	USP21	Q16539	MAPK14	T174	S171N	171	Missense	distal	-3	no	6.744	5.597	EPSD	TCGA	5.915	Loss
CMGC_MAPK_p38_MAPK14_ST	Q9UK80	USP21	Q16539	MAPK14	T174	S179P	179	Missense	distal	5	no	6.744	6.293	EPSD	TCGA;COSMIC	5.915	Down-regulation
CMGC_MAPK_p38_MAPK14_ST	Q9UK80	USP21	Q16539	MAPK14	T174	P167H	167	Missense	distal	-7	no	6.744	6.368	EPSD	TCGA;ICGC;COSMIC;CCLE	5.915	Down-regulation
CMGC_MAPK_p38_MAPK14_ST	Q9UK80	USP21	Q16539	MAPK14	S182	R189W	189	Missense	distal	7	no	6.766	6.077	EPSD	TCGA;ICGC;COSMIC	5.915	Down-regulation
CMGC_MAPK_p38_MAPK14_ST	Q9UK80	USP21	Q16539	MAPK14	S182	M185I	185	Missense	distal	3	no	6.766	6.824	EPSD	TCGA;ICGC;COSMIC	5.915	Up-regulation
CMGC_MAPK_p38_MAPK14_ST	Q9UK80	USP21	Q16539	MAPK14	S182	S179P	179	Missense	distal	-3	no	6.766	6.002	EPSD	TCGA;COSMIC	5.915	Down-regulation
CMGC_MAPK_p38_MAPK14_ST	Q9UK80	USP21	Q16539	MAPK14	S182	R189L	189	Missense	distal	7	no	6.766	6.347	EPSD	TCGA;ICGC;COSMIC	5.915	Down-regulation
CMGC_MAPK_p38_MAPK14_ST	Q9UK80	USP21	Q16539	MAPK14	S182	A188T	188	Missense	distal	6	no	6.766	6.749	EPSD	TCGA;ICGC;COSMIC	5.915	Down-regulation
CMGC_MAPK_p38_MAPK14_ST	Q9UK80	USP21	Q16539	MAPK14	S182	R189Q	189	Missense	distal	7	no	6.766	6.572	EPSD	TCGA;ICGC;COSMIC;CCLE	5.915	Down-regulation
CMGC_MAPK_p38_MAPK14_ST	Q9UK80	USP21	Q16539	MAPK14	S538	R536C	536	Missense	proximal	-2	no	11.440	10.505	PhosphoSitePlus	TCGA;ICGC;COSMIC	5.915	Down-regulation
CMGC_MAPK_p38_MAPK14_ST	Q9UK80	USP21	Q16539	MAPK14	S538	S538F	538	Missense	central	0	yes	11.440	0.000	PhosphoSitePlus	TCGA;ICGC;COSMIC	5.915	Loss
CMGC_MAPK_p38_MAPK14_ST	P04637	TP53	Q16539	MAPK14	S33	P27S	27	Missense	distal	-6	no	11.723	12.330	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	5.915	Up-regulation
CMGC_MAPK_p38_MAPK14_ST	P04637	TP53	Q16539	MAPK14	S33	P27L	27	Missense	distal	-6	no	11.723	11.110	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC;GDSC;CCLE	5.915	Down-regulation
CMGC_MAPK_p38_MAPK14_ST	P04637	TP53	Q16539	MAPK14	S46	D48N	48	Missense	proximal	2	no	11.214	11.444	PhosphoSitePlus;EPSD	TCGA;ICGC;COSMIC;GDSC;CCLE	5.915	Up-regulation
CMGC_MAPK_p38_MAPK14_ST	P04637	TP53	Q16539	MAPK14	T81	A79V	79	Missense	proximal	-2	no	7.344	6.929	EPSD	TCGA;ICGC;COSMIC	5.915	Down-regulation
CMGC_MAPK_p38_MAPK14_ST	P04637	TP53	Q16539	MAPK14	T81	P77L	77	Missense	distal	-4	no	7.344	7.856	EPSD	TCGA;ICGC;COSMIC	5.915	Up-regulation
CMGC_MAPK_p38_MAPK14_ST	P04637	TP53	Q16539	MAPK14	T81	P82L	82	Missense	proximal	1	no	7.344	-0.707	EPSD	TCGA;ICGC;COSMIC	5.915	Loss
CMGC_MAPK_p38_MAPK14_ST	P04637	TP53	Q16539	MAPK14	T81	A74T	74	Missense	distal	-7	no	7.344	7.161	EPSD	TCGA;ICGC;COSMIC	5.915	Down-regulation
CMGC_MAPK_p38_MAPK14_ST	P04637	TP53	Q16539	MAPK14	S127	K132N	132	Missense	distal	5	no	12.191	12.460	EPSD	TCGA;ICGC;COSMIC;GDSC;CCLE	5.915	Up-regulation
CMGC_MAPK_p38_MAPK14_ST	P04637	TP53	Q16539	MAPK14	S127	S121Y	121	Missense	distal	-6	no	12.191	11.425	EPSD	TCGA;ICGC;COSMIC	5.915	Down-regulation
CMGC_MAPK_p38_MAPK14_ST	P04637	TP53	Q16539	MAPK14	S127	M133K	133	Missense	distal	6	no	12.191	12.217	EPSD	TCGA;ICGC;COSMIC;CCLE	5.915	Up-regulation
CMGC_MAPK_p38_MAPK14_ST	P04637	TP53	Q16539	MAPK14	S127	K132E	132	Missense	distal	5	no	12.191	12.758	EPSD	TCGA;ICGC;COSMIC;GDSC;CCLE	5.915	Up-regulation
CMGC_MAPK_p38_MAPK14_ST	P04637	TP53	Q16539	MAPK14	S127	Y126C	126	Missense	proximal	-1	no	12.191	12.346	EPSD	TCGA;ICGC;COSMIC;GDSC	5.915	Up-regulation
CMGC_MAPK_p38_MAPK14_ST	P04637	TP53	Q16539	MAPK14	S127	S127P	127	Missense	central	0	yes	12.191	0.000	EPSD	TCGA;ICGC;COSMIC;GDSC;CCLE	5.915	Loss
CMGC_MAPK_p38_MAPK14_ST	P04637	TP53	Q16539	MAPK14	S127	Y126N	126	Missense	proximal	-1	no	12.191	12.262	EPSD	TCGA;ICGC;COSMIC	5.915	Up-regulation
CMGC_MAPK_p38_MAPK14_ST	P04637	TP53	Q16539	MAPK14	S127	L130V	130	Missense	distal	3	no	12.191	12.159	EPSD	TCGA;ICGC;COSMIC;GDSC;CCLE	5.915	Down-regulation
CMGC_MAPK_p38_MAPK14_ST	P04637	TP53	Q16539	MAPK14	S127	K132T	132	Missense	distal	5	no	12.191	12.630	EPSD	TCGA;ICGC;COSMIC;GDSC;CCLE	5.915	Up-regulation
CMGC_MAPK_p38_MAPK14_ST	P04637	TP53	Q16539	MAPK14	S127	S127Y	127	Missense	central	0	yes	12.191	0.000	EPSD	TCGA;ICGC;COSMIC	5.915	Loss
CMGC_MAPK_p38_MAPK14_ST	P04637	TP53	Q16539	MAPK14	S127	S127F	127	Missense	central	0	yes	12.191	0.000	EPSD	TCGA;ICGC;COSMIC;CCLE	5.915	Loss
CMGC_MAPK_p38_MAPK14_ST	P04637	TP53	Q16539	MAPK14	S127	M133R	133	Missense	distal	6	no	12.191	12.142	EPSD	TCGA;ICGC;COSMIC	5.915	Down-regulation
CMGC_MAPK_p38_MAPK14_ST	P04637	TP53	Q16539	MAPK14	S127	K132R	132	Missense	distal	5	no	12.191	12.486	EPSD	TCGA;ICGC;COSMIC;GDSC;CCLE	5.915	Up-regulation
CMGC_MAPK_p38_MAPK14_ST	P04637	TP53	Q16539	MAPK14	S127	F134L	134	Missense	distal	7	no	12.191	12.676	EPSD	TCGA;ICGC;COSMIC;CCLE	5.915	Up-regulation
CMGC_MAPK_p38_MAPK14_ST	P04637	TP53	Q16539	MAPK14	S127	Y126S	126	Missense	proximal	-1	no	12.191	12.190	EPSD	TCGA;ICGC;COSMIC	5.915	Down-regulation
CMGC_MAPK_p38_MAPK14_ST	P04637	TP53	Q16539	MAPK14	S127	L130P	130	Missense	distal	3	no	12.191	12.157	EPSD	TCGA;ICGC;COSMIC	5.915	Down-regulation
CMGC_MAPK_p38_MAPK14_ST	P04637	TP53	Q16539	MAPK14	S127	L130F	130	Missense	distal	3	no	12.191	12.225	EPSD	TCGA;ICGC;COSMIC;CCLE	5.915	Up-regulation
CMGC_MAPK_p38_MAPK14_ST	P04637	TP53	Q16539	MAPK14	S127	F134V	134	Missense	distal	7	no	12.191	12.974	EPSD	TCGA;ICGC;COSMIC	5.915	Up-regulation
CMGC_MAPK_p38_MAPK14_ST	P04637	TP53	Q16539	MAPK14	S127	T125M	125	Missense	proximal	-2	no	12.191	12.099	EPSD	TCGA;ICGC;COSMIC;GDSC	5.915	Down-regulation
CMGC_MAPK_p38_MAPK14_ST	P04637	TP53	Q16539	MAPK14	S127	Y126D	126	Missense	proximal	-1	no	12.191	12.447	EPSD	TCGA;ICGC;COSMIC;GDSC	5.915	Up-regulation
CMGC_MAPK_p38_MAPK14_ST	P04637	TP53	Q16539	MAPK14	S127	K120E	120	Missense	distal	-7	no	12.191	12.245	EPSD	TCGA;ICGC;COSMIC	5.915	Up-regulation
CMGC_MAPK_p38_MAPK14_ST	P04637	TP53	Q16539	MAPK14	S127	N131S	131	Missense	distal	4	no	12.191	12.708	EPSD	TCGA;ICGC;COSMIC	5.915	Up-regulation
CMGC_MAPK_p38_MAPK14_ST	P04637	TP53	Q16539	MAPK14	S127	T125P	125	Missense	proximal	-2	no	12.191	12.911	EPSD	TCGA;ICGC;COSMIC;CCLE	5.915	Up-regulation
CMGC_MAPK_p38_MAPK14_ST	P04637	TP53	Q16539	MAPK14	S127	S127C	127	Missense	central	0	yes	12.191	0.000	EPSD	TCGA;ICGC;COSMIC;CCLE	5.915	Loss
CMGC_MAPK_p38_MAPK14_ST	P04637	TP53	Q16539	MAPK14	S127	N131I	131	Missense	distal	4	no	12.191	11.919	EPSD	TCGA;ICGC;COSMIC	5.915	Down-regulation
CMGC_MAPK_p38_MAPK14_ST	P04637	TP53	Q16539	MAPK14	S127	Y126H	126	Missense	proximal	-1	no	12.191	12.238	EPSD	TCGA;ICGC;COSMIC;GDSC	5.915	Up-regulation
CMGC_MAPK_p38_MAPK14_ST	P04637	TP53	Q16539	MAPK14	S127	K132Q	132	Missense	distal	5	no	12.191	12.137	EPSD	TCGA;ICGC;COSMIC;GDSC;CCLE	5.915	Down-regulation
CMGC_MAPK_p38_MAPK14_ST	P04637	TP53	Q16539	MAPK14	S127	L130R	130	Missense	distal	3	no	12.191	12.145	EPSD	TCGA;ICGC;COSMIC;CCLE	5.915	Down-regulation
CMGC_MAPK_p38_MAPK14_ST	P04637	TP53	Q16539	MAPK14	S149	W146S	146	Missense	distal	-3	no	5.322	7.166	EPSD	TCGA;ICGC;COSMIC	5.915	Gain
CMGC_MAPK_p38_MAPK14_ST	P04637	TP53	Q16539	MAPK14	S149	V143E	143	Missense	distal	-6	no	5.322	6.182	EPSD	TCGA;ICGC;COSMIC	5.915	Gain
CMGC_MAPK_p38_MAPK14_ST	P04637	TP53	Q16539	MAPK14	T150	W146S	146	Missense	distal	-4	no	7.036	6.396	EPSD	TCGA;ICGC;COSMIC	5.915	Down-regulation
CMGC_MAPK_p38_MAPK14_ST	P04637	TP53	Q16539	MAPK14	T150	P152L	152	Missense	proximal	2	no	7.036	6.924	EPSD	TCGA;ICGC;COSMIC;GDSC;CCLE	5.915	Down-regulation
CMGC_MAPK_p38_MAPK14_ST	P04637	TP53	Q16539	MAPK14	T150	D148N	148	Missense	proximal	-2	no	7.036	7.550	EPSD	TCGA;ICGC;COSMIC	5.915	Up-regulation
CMGC_MAPK_p38_MAPK14_ST	P04637	TP53	Q16539	MAPK14	T150	P151H	151	Missense	proximal	1	no	7.036	-6.618	EPSD	TCGA;ICGC;COSMIC;GDSC;CCLE	5.915	Loss
CMGC_MAPK_p38_MAPK14_ST	P04637	TP53	Q16539	MAPK14	T150	P151A	151	Missense	proximal	1	no	7.036	0.718	EPSD	TCGA;ICGC;COSMIC;CCLE	5.915	Loss
CMGC_MAPK_p38_MAPK14_ST	P04637	TP53	Q16539	MAPK14	T150	R156P	156	Missense	distal	6	no	7.036	7.048	EPSD	TCGA;ICGC;COSMIC;GDSC;CCLE	5.915	Up-regulation
CMGC_MAPK_p38_MAPK14_ST	P04637	TP53	Q16539	MAPK14	T150	V143A	143	Missense	distal	-7	no	7.036	7.854	EPSD	TCGA;ICGC;COSMIC;GDSC;CCLE	5.915	Up-regulation
CMGC_MAPK_p38_MAPK14_ST	P04637	TP53	Q16539	MAPK14	T150	P151S	151	Missense	proximal	1	no	7.036	-0.248	EPSD	TCGA;ICGC;COSMIC;GDSC;CCLE	5.915	Loss
CMGC_MAPK_p38_MAPK14_ST	P04637	TP53	Q16539	MAPK14	T150	V157F	157	Missense	distal	7	no	7.036	6.253	EPSD	TCGA;ICGC;COSMIC;GDSC;CCLE	5.915	Down-regulation
CMGC_MAPK_p38_MAPK14_ST	P04637	TP53	Q16539	MAPK14	T150	V157G	157	Missense	distal	7	no	7.036	6.979	EPSD	TCGA;ICGC;COSMIC	5.915	Down-regulation
CMGC_MAPK_p38_MAPK14_ST	P04637	TP53	Q16539	MAPK14	T150	V157D	157	Missense	distal	7	no	7.036	7.145	EPSD	TCGA;ICGC;COSMIC	5.915	Up-regulation
CMGC_MAPK_p38_MAPK14_ST	P04637	TP53	Q16539	MAPK14	T150	L145R	145	Missense	distal	-5	no	7.036	6.525	EPSD	TCGA;ICGC;COSMIC;GDSC;CCLE	5.915	Down-regulation
CMGC_MAPK_p38_MAPK14_ST	P04637	TP53	Q16539	MAPK14	T150	T155I	155	Missense	distal	5	no	7.036	6.110	EPSD	TCGA;ICGC;COSMIC;CCLE	5.915	Down-regulation
CMGC_MAPK_p38_MAPK14_ST	P04637	TP53	Q16539	MAPK14	T150	V143M	143	Missense	distal	-7	no	7.036	7.725	EPSD	TCGA;ICGC;COSMIC;GDSC;CCLE	5.915	Up-regulation
CMGC_MAPK_p38_MAPK14_ST	P04637	TP53	Q16539	MAPK14	T150	T155N	155	Missense	distal	5	no	7.036	6.867	EPSD	TCGA;ICGC;COSMIC;GDSC;CCLE	5.915	Down-regulation
CMGC_MAPK_p38_MAPK14_ST	P04637	TP53	Q16539	MAPK14	T150	P152S	152	Missense	proximal	2	no	7.036	7.413	EPSD	TCGA;ICGC;COSMIC;CCLE	5.915	Up-regulation
CMGC_MAPK_p38_MAPK14_ST	P04637	TP53	Q16539	MAPK14	T150	R156C	156	Missense	distal	6	no	7.036	6.762	EPSD	TCGA;ICGC;COSMIC	5.915	Down-regulation
CMGC_MAPK_p38_MAPK14_ST	P04637	TP53	Q16539	MAPK14	T150	P151T	151	Missense	proximal	1	no	7.036	-0.417	EPSD	TCGA;ICGC;COSMIC	5.915	Loss
CMGC_MAPK_p38_MAPK14_ST	P04637	TP53	Q16539	MAPK14	T150	T155P	155	Missense	distal	5	no	7.036	6.752	EPSD	TCGA;ICGC;COSMIC;CCLE	5.915	Down-regulation
CMGC_MAPK_p38_MAPK14_ST	P04637	TP53	Q16539	MAPK14	T150	V143G	143	Missense	distal	-7	no	7.036	7.674	EPSD	TCGA;ICGC;COSMIC	5.915	Up-regulation
CMGC_MAPK_p38_MAPK14_ST	P04637	TP53	Q16539	MAPK14	T150	P152Q	152	Missense	proximal	2	no	7.036	6.841	EPSD	TCGA;ICGC;COSMIC	5.915	Down-regulation
CMGC_MAPK_p38_MAPK14_ST	P04637	TP53	Q16539	MAPK14	T150	R156H	156	Missense	distal	6	no	7.036	6.929	EPSD	TCGA;ICGC;COSMIC	5.915	Down-regulation
CMGC_MAPK_p38_MAPK14_ST	P04637	TP53	Q16539	MAPK14	T150	L145P	145	Missense	distal	-5	no	7.036	6.755	EPSD	TCGA;ICGC;COSMIC	5.915	Down-regulation
CMGC_MAPK_p38_MAPK14_ST	P04637	TP53	Q16539	MAPK14	T150	Q144L	144	Missense	distal	-6	no	7.036	6.592	EPSD	TCGA;ICGC;COSMIC	5.915	Down-regulation
CMGC_MAPK_p38_MAPK14_ST	P04637	TP53	Q16539	MAPK14	T150	Q144H	144	Missense	distal	-6	no	7.036	6.743	EPSD	TCGA;ICGC;COSMIC	5.915	Down-regulation
CMGC_MAPK_p38_MAPK14_ST	P04637	TP53	Q16539	MAPK14	T150	G154V	154	Missense	distal	4	no	7.036	6.528	EPSD	TCGA;ICGC;COSMIC;GDSC;CCLE	5.915	Down-regulation
CMGC_MAPK_p38_MAPK14_ST	P04637	TP53	Q16539	MAPK14	T150	V157L	157	Missense	distal	7	no	7.036	6.738	EPSD	TCGA;ICGC;COSMIC	5.915	Down-regulation
CMGC_MAPK_p38_MAPK14_ST	P04637	TP53	Q16539	MAPK14	T150	P151R	151	Missense	proximal	1	no	7.036	-0.899	EPSD	TCGA;ICGC;COSMIC	5.915	Loss
CMGC_MAPK_p38_MAPK14_ST	P04637	TP53	Q16539	MAPK14	T150	Q144P	144	Missense	distal	-6	no	7.036	7.205	EPSD	TCGA;ICGC;COSMIC	5.915	Up-regulation
CMGC_MAPK_p38_MAPK14_ST	P04637	TP53	Q16539	MAPK14	T150	V143E	143	Missense	distal	-7	no	7.036	7.892	EPSD	TCGA;ICGC;COSMIC	5.915	Up-regulation
CMGC_MAPK_p38_MAPK14_ST	P04637	TP53	Q16539	MAPK14	T150	R156G	156	Missense	distal	6	no	7.036	7.158	EPSD	TCGA;ICGC;COSMIC	5.915	Up-regulation
CMGC_MAPK_p38_MAPK14_ST	P04637	TP53	Q16539	MAPK14	T150	P151L	151	Missense	proximal	1	no	7.036	-1.015	EPSD	TCGA;ICGC;COSMIC	5.915	Loss
CMGC_MAPK_p38_MAPK14_ST	P04637	TP53	Q16539	MAPK14	T155	R156P	156	Missense	proximal	1	no	4.344	12.279	EPSD	TCGA;ICGC;COSMIC;GDSC;CCLE	5.915	Gain
CMGC_MAPK_p38_MAPK14_ST	P04637	TP53	Q16539	MAPK14	T211	R213Q	213	Missense	proximal	2	no	6.953	6.527	EPSD	TCGA;ICGC;COSMIC;GDSC;CCLE	5.915	Down-regulation
CMGC_MAPK_p38_MAPK14_ST	P04637	TP53	Q16539	MAPK14	T211	E204Q	204	Missense	distal	-7	no	6.953	6.540	EPSD	TCGA;ICGC;COSMIC	5.915	Down-regulation
CMGC_MAPK_p38_MAPK14_ST	P04637	TP53	Q16539	MAPK14	T211	D208N	208	Missense	distal	-3	no	6.953	6.795	EPSD	TCGA;ICGC;COSMIC	5.915	Down-regulation
CMGC_MAPK_p38_MAPK14_ST	P04637	TP53	Q16539	MAPK14	T211	H214R	214	Missense	distal	3	no	6.953	6.882	EPSD	TCGA;ICGC;COSMIC;GDSC;CCLE	5.915	Down-regulation
CMGC_MAPK_p38_MAPK14_ST	P04637	TP53	Q16539	MAPK14	T211	V218E	218	Missense	distal	7	no	6.953	7.257	EPSD	TCGA;ICGC;COSMIC	5.915	Up-regulation
CMGC_MAPK_p38_MAPK14_ST	P04637	TP53	Q16539	MAPK14	T211	S215I	215	Missense	distal	4	no	6.953	6.165	EPSD	TCGA;ICGC;COSMIC;GDSC;CCLE	5.915	Down-regulation
CMGC_MAPK_p38_MAPK14_ST	P04637	TP53	Q16539	MAPK14	T211	V216M	216	Missense	distal	5	no	6.953	7.131	EPSD	TCGA;ICGC;COSMIC;GDSC;CCLE	5.915	Up-regulation
CMGC_MAPK_p38_MAPK14_ST	P04637	TP53	Q16539	MAPK14	T211	Y205C	205	Missense	distal	-6	no	6.953	6.427	EPSD	TCGA;ICGC;COSMIC;GDSC;CCLE	5.915	Down-regulation
CMGC_MAPK_p38_MAPK14_ST	P04637	TP53	Q16539	MAPK14	T211	Y205N	205	Missense	distal	-6	no	6.953	7.296	EPSD	TCGA;ICGC;COSMIC	5.915	Up-regulation
CMGC_MAPK_p38_MAPK14_ST	P04637	TP53	Q16539	MAPK14	T211	S215N	215	Missense	distal	4	no	6.953	6.437	EPSD	TCGA;ICGC;COSMIC;GDSC;CCLE	5.915	Down-regulation
CMGC_MAPK_p38_MAPK14_ST	P04637	TP53	Q16539	MAPK14	T211	T211I	211	Missense	central	0	yes	6.953	0.000	EPSD	TCGA;ICGC;COSMIC;CCLE	5.915	Loss
CMGC_MAPK_p38_MAPK14_ST	P04637	TP53	Q16539	MAPK14	T211	V216G	216	Missense	distal	5	no	6.953	7.355	EPSD	TCGA;ICGC;COSMIC	5.915	Up-regulation
CMGC_MAPK_p38_MAPK14_ST	P04637	TP53	Q16539	MAPK14	T211	R213L	213	Missense	proximal	2	no	6.953	6.610	EPSD	TCGA;ICGC;COSMIC;GDSC;CCLE	5.915	Down-regulation
CMGC_MAPK_p38_MAPK14_ST	P04637	TP53	Q16539	MAPK14	T211	V216E	216	Missense	distal	5	no	6.953	7.573	EPSD	TCGA;ICGC;COSMIC	5.915	Up-regulation
CMGC_MAPK_p38_MAPK14_ST	P04637	TP53	Q16539	MAPK14	T211	R209K	209	Missense	proximal	-2	no	6.953	6.350	EPSD	TCGA;COSMIC	5.915	Down-regulation
CMGC_MAPK_p38_MAPK14_ST	P04637	TP53	Q16539	MAPK14	T211	V218G	218	Missense	distal	7	no	6.953	6.896	EPSD	TCGA;ICGC;COSMIC	5.915	Down-regulation
CMGC_MAPK_p38_MAPK14_ST	P04637	TP53	Q16539	MAPK14	T211	R213P	213	Missense	proximal	2	no	6.953	6.722	EPSD	TCGA;ICGC;COSMIC	5.915	Down-regulation
CMGC_MAPK_p38_MAPK14_ST	P04637	TP53	Q16539	MAPK14	T211	H214L	214	Missense	distal	3	no	6.953	6.929	EPSD	TCGA;ICGC;COSMIC	5.915	Down-regulation
CMGC_MAPK_p38_MAPK14_ST	P04637	TP53	Q16539	MAPK14	T211	Y205H	205	Missense	distal	-6	no	6.953	6.650	EPSD	TCGA;ICGC;COSMIC;CCLE	5.915	Down-regulation
CMGC_MAPK_p38_MAPK14_ST	P04637	TP53	Q16539	MAPK14	T211	V216L	216	Missense	distal	5	no	6.953	6.663	EPSD	TCGA;ICGC;COSMIC;GDSC;CCLE	5.915	Down-regulation
CMGC_MAPK_p38_MAPK14_ST	P04637	TP53	Q16539	MAPK14	T211	D208G	208	Missense	distal	-3	no	6.953	7.004	EPSD	TCGA;ICGC;COSMIC	5.915	Up-regulation
CMGC_MAPK_p38_MAPK14_ST	P04637	TP53	Q16539	MAPK14	T211	Y205S	205	Missense	distal	-6	no	6.953	7.719	EPSD	TCGA;ICGC;COSMIC	5.915	Up-regulation
CMGC_MAPK_p38_MAPK14_ST	P04637	TP53	Q16539	MAPK14	T211	S215G	215	Missense	distal	4	no	6.953	6.721	EPSD	TCGA;ICGC;COSMIC;GDSC;CCLE	5.915	Down-regulation
CMGC_MAPK_p38_MAPK14_ST	P04637	TP53	Q16539	MAPK14	T211	R209S	209	Missense	proximal	-2	no	6.953	7.153	EPSD	TCGA;ICGC;COSMIC	5.915	Up-regulation
CMGC_MAPK_p38_MAPK14_ST	P04637	TP53	Q16539	MAPK14	T211	R213G	213	Missense	proximal	2	no	6.953	6.870	EPSD	TCGA;ICGC;COSMIC	5.915	Down-regulation
CMGC_MAPK_p38_MAPK14_ST	P04637	TP53	Q16539	MAPK14	T211	Y205F	205	Missense	distal	-6	no	6.953	5.955	EPSD	TCGA;ICGC;COSMIC;GDSC;CCLE	5.915	Down-regulation
CMGC_MAPK_p38_MAPK14_ST	P04637	TP53	Q16539	MAPK14	T211	Y205D	205	Missense	distal	-6	no	6.953	6.970	EPSD	TCGA;ICGC;COSMIC	5.915	Up-regulation
CMGC_MAPK_p38_MAPK14_ST	P04637	TP53	Q16539	MAPK14	T211	S215R	215	Missense	distal	4	no	6.953	6.236	EPSD	TCGA;ICGC;COSMIC;GDSC;CCLE	5.915	Down-regulation
CMGC_MAPK_p38_MAPK14_ST	P04637	TP53	Q16539	MAPK14	T211	R209I	209	Missense	proximal	-2	no	6.953	6.824	EPSD	TCGA;ICGC;COSMIC	5.915	Down-regulation
CMGC_MAPK_p38_MAPK14_ST	P04637	TP53	Q16539	MAPK14	T211	T211A	211	Missense	central	0	yes	6.953	0.000	EPSD	TCGA;ICGC;COSMIC;CCLE	5.915	Loss
CMGC_MAPK_p38_MAPK14_ST	P04637	TP53	Q16539	MAPK14	T211	E204D	204	Missense	distal	-7	no	6.953	6.372	EPSD	TCGA;ICGC;COSMIC	5.915	Down-regulation
CMGC_MAPK_p38_MAPK14_ST	P04637	TP53	Q16539	MAPK14	S269	G266R	266	Missense	distal	-3	no	4.904	6.354	EPSD	TCGA;ICGC;COSMIC;GDSC;CCLE	5.915	Gain
CMGC_MAPK_p38_MAPK14_ST	P04637	TP53	Q16539	MAPK14	S315	K319N	319	Missense	distal	4	no	10.517	9.967	EPSD	TCGA;ICGC;COSMIC	5.915	Down-regulation
CMGC_MAPK_p38_MAPK14_ST	P04637	TP53	Q16539	MAPK14	S315	K320E	320	Missense	distal	5	no	10.517	11.084	EPSD	TCGA;ICGC;COSMIC	5.915	Up-regulation
CMGC_MAPK_p38_MAPK14_ST	P04637	TP53	Q16539	MAPK14	S315	S315C	315	Missense	central	0	yes	10.517	0.000	EPSD	TCGA;ICGC;COSMIC	5.915	Loss
CMGC_MAPK_p38_MAPK14_ST	Q9UIG0	BAZ1B	Q16539	MAPK14	S158	E164D	164	Missense	distal	6	no	10.399	10.298	PhosphoSitePlus	TCGA;ICGC	5.915	Down-regulation
CMGC_MAPK_p38_MAPK14_ST	Q9UIG0	BAZ1B	Q16539	MAPK14	S161	S166Y	166	Missense	distal	5	no	5.976	5.697	EPSD	TCGA	5.915	Loss
CMGC_MAPK_p38_MAPK14_ST	Q9UIG0	BAZ1B	Q16539	MAPK14	S161	Q168E	168	Missense	distal	7	no	5.976	6.353	EPSD	TCGA;ICGC;COSMIC	5.915	Up-regulation
CMGC_MAPK_p38_MAPK14_ST	Q9UIG0	BAZ1B	Q16539	MAPK14	S161	E164D	164	Missense	distal	3	no	5.976	6.031	EPSD	TCGA;ICGC	5.915	Up-regulation
CMGC_MAPK_p38_MAPK14_ST	Q9UIG0	BAZ1B	Q16539	MAPK14	S197	S204L	204	Missense	distal	7	no	10.765	10.380	EPSD	TCGA;ICGC;COSMIC	5.915	Down-regulation
CMGC_MAPK_p38_MAPK14_ST	Q9UIG0	BAZ1B	Q16539	MAPK14	S197	R199Q	199	Missense	proximal	2	no	10.765	10.339	EPSD	TCGA;ICGC;COSMIC	5.915	Down-regulation
CMGC_MAPK_p38_MAPK14_ST	Q9UIG0	BAZ1B	Q16539	MAPK14	S197	P202R	202	Missense	distal	5	no	10.765	10.905	EPSD	TCGA;ICGC;COSMIC	5.915	Up-regulation
CMGC_MAPK_p38_MAPK14_ST	Q9UIG0	BAZ1B	Q16539	MAPK14	S197	R195H	195	Missense	proximal	-2	no	10.765	9.187	EPSD	TCGA;ICGC	5.915	Down-regulation
CMGC_MAPK_p38_MAPK14_ST	Q9UIG0	BAZ1B	Q16539	MAPK14	S197	D192N	192	Missense	distal	-5	no	10.765	10.605	EPSD	TCGA	5.915	Down-regulation
CMGC_MAPK_p38_MAPK14_ST	Q9UIG0	BAZ1B	Q16539	MAPK14	T266	L262V	262	Missense	distal	-4	no	5.926	5.648	EPSD	TCGA;ICGC;COSMIC	5.915	Loss
CMGC_MAPK_p38_MAPK14_ST	Q9UIG0	BAZ1B	Q16539	MAPK14	T266	P271H	271	Missense	distal	5	no	5.926	5.371	EPSD	TCGA;ICGC;COSMIC	5.915	Loss
CMGC_MAPK_p38_MAPK14_ST	Q9UIG0	BAZ1B	Q16539	MAPK14	S312	T310S	310	Missense	proximal	-2	no	11.224	11.455	EPSD	TCGA;ICGC;COSMIC	5.915	Up-regulation
CMGC_MAPK_p38_MAPK14_ST	Q9UIG0	BAZ1B	Q16539	MAPK14	S349	L342F	342	Missense	distal	-7	no	8.838	8.372	EPSD	TCGA;ICGC;COSMIC	5.915	Down-regulation
CMGC_MAPK_p38_MAPK14_ST	Q9UIG0	BAZ1B	Q16539	MAPK14	S349	G348D	348	Missense	proximal	-1	no	8.838	8.882	EPSD	TCGA;ICGC	5.915	Up-regulation
CMGC_MAPK_p38_MAPK14_ST	Q9UIG0	BAZ1B	Q16539	MAPK14	S361	P362H	362	Missense	proximal	1	no	11.743	-1.911	EPSD	TCGA;ICGC;COSMIC	5.915	Loss
CMGC_MAPK_p38_MAPK14_ST	Q9UIG0	BAZ1B	Q16539	MAPK14	S361	E364Q	364	Missense	distal	3	no	11.743	11.816	EPSD	TCGA;ICGC;COSMIC	5.915	Up-regulation
CMGC_MAPK_p38_MAPK14_ST	Q9UIG0	BAZ1B	Q16539	MAPK14	S361	P362S	362	Missense	proximal	1	no	11.743	4.459	EPSD	TCGA;ICGC;COSMIC	5.915	Loss
CMGC_MAPK_p38_MAPK14_ST	Q9UIG0	BAZ1B	Q16539	MAPK14	S374	H379Q	379	Missense	distal	5	no	8.770	9.115	EPSD	TCGA;ICGC;COSMIC	5.915	Up-regulation
CMGC_MAPK_p38_MAPK14_ST	Q9UIG0	BAZ1B	Q16539	MAPK14	S374	M372I	372	Missense	proximal	-2	no	8.770	8.763	EPSD	TCGA;ICGC;COSMIC	5.915	Down-regulation
CMGC_MAPK_p38_MAPK14_ST	Q9UIG0	BAZ1B	Q16539	MAPK14	S374	N376D	376	Missense	proximal	2	no	8.770	8.540	EPSD	TCGA;ICGC;COSMIC	5.915	Down-regulation
CMGC_MAPK_p38_MAPK14_ST	Q9UIG0	BAZ1B	Q16539	MAPK14	S374	P375S	375	Missense	proximal	1	no	8.770	1.486	EPSD	TCGA;ICGC;COSMIC	5.915	Loss
CMGC_MAPK_p38_MAPK14_ST	Q9UIG0	BAZ1B	Q16539	MAPK14	S374	S374L	374	Missense	central	0	yes	8.770	0.000	EPSD	TCGA;ICGC;COSMIC	5.915	Loss
CMGC_MAPK_p38_MAPK14_ST	Q9UIG0	BAZ1B	Q16539	MAPK14	S423	L428P	428	Missense	distal	5	no	9.033	9.530	EPSD	TCGA;ICGC;COSMIC	5.915	Up-regulation
CMGC_MAPK_p38_MAPK14_ST	Q9UIG0	BAZ1B	Q16539	MAPK14	S423	S417F	417	Missense	distal	-6	no	9.033	7.268	EPSD	TCGA;ICGC;COSMIC	5.915	Down-regulation
CMGC_MAPK_p38_MAPK14_ST	Q9UIG0	BAZ1B	Q16539	MAPK14	T430	L428P	428	Missense	proximal	-2	no	10.147	11.527	EPSD	TCGA;ICGC;COSMIC	5.915	Up-regulation
CMGC_MAPK_p38_MAPK14_ST	Q9UIG0	BAZ1B	Q16539	MAPK14	T430	P431S	431	Missense	proximal	1	no	10.147	2.863	EPSD	TCGA;ICGC;COSMIC	5.915	Loss
CMGC_MAPK_p38_MAPK14_ST	Q9UIG0	BAZ1B	Q16539	MAPK14	S457	R455Q	455	Missense	proximal	-2	no	6.820	6.493	EPSD	TCGA;ICGC	5.915	Down-regulation
CMGC_MAPK_p38_MAPK14_ST	Q9UIG0	BAZ1B	Q16539	MAPK14	S457	T460A	460	Missense	distal	3	no	6.820	6.821	EPSD	TCGA;ICGC;COSMIC;GDSC;CCLE	5.915	Up-regulation
CMGC_MAPK_p38_MAPK14_ST	Q9UIG0	BAZ1B	Q16539	MAPK14	S457	G459D	459	Missense	proximal	2	no	6.820	6.563	EPSD	TCGA;ICGC;COSMIC	5.915	Down-regulation
CMGC_MAPK_p38_MAPK14_ST	Q9UIG0	BAZ1B	Q16539	MAPK14	S457	R452Q	452	Missense	distal	-5	no	6.820	6.778	EPSD	TCGA;ICGC;COSMIC	5.915	Down-regulation
CMGC_MAPK_p38_MAPK14_ST	Q9UIG0	BAZ1B	Q16539	MAPK14	T460	R455Q	455	Missense	distal	-5	no	14.838	14.795	EPSD	TCGA;ICGC	5.915	Down-regulation
CMGC_MAPK_p38_MAPK14_ST	Q9UIG0	BAZ1B	Q16539	MAPK14	T460	T460A	460	Missense	central	0	yes	14.838	0.000	EPSD	TCGA;ICGC;COSMIC;GDSC;CCLE	5.915	Loss
CMGC_MAPK_p38_MAPK14_ST	Q9UIG0	BAZ1B	Q16539	MAPK14	T460	G459D	459	Missense	proximal	-1	no	14.838	14.881	EPSD	TCGA;ICGC;COSMIC	5.915	Up-regulation
CMGC_MAPK_p38_MAPK14_ST	Q9UIG0	BAZ1B	Q16539	MAPK14	S539	E540Q	540	Missense	proximal	1	no	6.099	6.650	EPSD	TCGA;ICGC;COSMIC	5.915	Up-regulation
CMGC_MAPK_p38_MAPK14_ST	Q9UIG0	BAZ1B	Q16539	MAPK14	S539	R543W	543	Missense	distal	4	no	6.099	4.824	EPSD	TCGA;ICGC;COSMIC	5.915	Loss
CMGC_MAPK_p38_MAPK14_ST	Q9UIG0	BAZ1B	Q16539	MAPK14	S699	E703V	703	Missense	distal	4	no	6.660	5.421	EPSD	TCGA;ICGC;COSMIC	5.915	Loss
CMGC_MAPK_p38_MAPK14_ST	Q9UIG0	BAZ1B	Q16539	MAPK14	S699	R697C	697	Missense	proximal	-2	no	6.660	5.725	EPSD	TCGA;ICGC;COSMIC	5.915	Loss
CMGC_MAPK_p38_MAPK14_ST	Q9UIG0	BAZ1B	Q16539	MAPK14	S699	R693W	693	Missense	distal	-6	no	6.660	5.343	EPSD	TCGA;ICGC;COSMIC	5.915	Loss
CMGC_MAPK_p38_MAPK14_ST	Q9UIG0	BAZ1B	Q16539	MAPK14	S716	D721E	721	Missense	distal	5	no	5.702	6.208	EPSD	TCGA;ICGC;COSMIC	5.915	Gain
CMGC_MAPK_p38_MAPK14_ST	Q9UIG0	BAZ1B	Q16539	MAPK14	S716	K714T	714	Missense	proximal	-2	no	5.702	6.274	EPSD	TCGA;ICGC	5.915	Gain
CMGC_MAPK_p38_MAPK14_ST	Q9UIG0	BAZ1B	Q16539	MAPK14	T983	V977I	977	Missense	distal	-6	no	9.006	8.741	EPSD	TCGA;ICGC;COSMIC	5.915	Down-regulation
CMGC_MAPK_p38_MAPK14_ST	Q9UIG0	BAZ1B	Q16539	MAPK14	S1361	R1365S	1365	Missense	distal	4	no	6.703	7.420	EPSD	TCGA;ICGC;COSMIC	5.915	Up-regulation
CMGC_MAPK_p38_MAPK14_ST	Q9UIG0	BAZ1B	Q16539	MAPK14	S1361	P1363S	1363	Missense	proximal	2	no	6.703	7.080	EPSD	TCGA;ICGC;COSMIC	5.915	Up-regulation
CMGC_MAPK_p38_MAPK14_ST	Q15717	ELAVL1	Q16539	MAPK14	S41	R37Q	37	Missense	distal	-4	no	5.862	6.230	EPSD	TCGA;ICGC;COSMIC	5.915	Gain
CMGC_MAPK_p38_MAPK14_ST	Q15717	ELAVL1	Q16539	MAPK14	S100	I103M	103	Missense	distal	3	no	6.812	6.753	EPSD	TCGA;ICGC;COSMIC	5.915	Down-regulation
CMGC_MAPK_p38_MAPK14_ST	Q15717	ELAVL1	Q16539	MAPK14	T118	Q119H	119	Missense	proximal	1	no	8.701	2.255	PhosphoSitePlus	TCGA;ICGC;COSMIC	5.915	Loss
CMGC_MAPK_p38_MAPK14_ST	Q15717	ELAVL1	Q16539	MAPK14	T118	G112V	112	Missense	distal	-6	no	8.701	8.151	PhosphoSitePlus	TCGA;ICGC;COSMIC	5.915	Down-regulation
CMGC_MAPK_p38_MAPK14_ST	Q15717	ELAVL1	Q16539	MAPK14	T118	V122L	122	Missense	distal	4	no	8.701	8.362	PhosphoSitePlus	TCGA;ICGC;COSMIC	5.915	Down-regulation
CMGC_MAPK_p38_MAPK14_ST	Q15717	ELAVL1	Q16539	MAPK14	T118	P114L	114	Missense	distal	-4	no	8.701	9.213	PhosphoSitePlus	TCGA;ICGC;COSMIC	5.915	Up-regulation
CMGC_MAPK_p38_MAPK14_ST	Q15717	ELAVL1	Q16539	MAPK14	S202	H201Q	201	Missense	proximal	-1	no	7.397	7.330	EPSD	TCGA;ICGC	5.915	Down-regulation
CMGC_MAPK_p38_MAPK14_ST	Q15717	ELAVL1	Q16539	MAPK14	S221	R217T	217	Missense	distal	-4	no	8.107	8.373	EPSD	TCGA;ICGC;COSMIC	5.915	Up-regulation
CMGC_MAPK_p38_MAPK14_ST	Q15717	ELAVL1	Q16539	MAPK14	S221	D226N	226	Missense	distal	5	no	8.107	8.316	EPSD	TCGA;ICGC;COSMIC	5.915	Up-regulation
CMGC_MAPK_p38_MAPK14_ST	P31645	SLC6A4	Q16539	MAPK14	S52	A55T	55	Missense	distal	3	no	9.852	9.851	EPSD	TCGA;ICGC;COSMIC	5.915	Down-regulation
CMGC_MAPK_p38_MAPK14_ST	P31645	SLC6A4	Q16539	MAPK14	S52	A55V	55	Missense	distal	3	no	9.852	9.880	EPSD	TCGA;ICGC;COSMIC	5.915	Up-regulation
CMGC_MAPK_p38_MAPK14_ST	P31645	SLC6A4	Q16539	MAPK14	S559	L557P	557	Missense	proximal	-2	no	5.752	7.132	EPSD	TCGA;ICGC;COSMIC	5.915	Gain
CMGC_MAPK_p38_MAPK14_ST	P31645	SLC6A4	Q16539	MAPK14	T613	R607C	607	Missense	distal	-6	no	8.840	7.654	EPSD	TCGA;ICGC	5.915	Down-regulation
CMGC_MAPK_p38_MAPK14_ST	Q9NQU5	PAK6	Q16539	MAPK14	S104	R103H	103	Missense	proximal	-1	no	12.483	12.639	EPSD	TCGA;ICGC;COSMIC	5.915	Up-regulation
CMGC_MAPK_p38_MAPK14_ST	Q9NQU5	PAK6	Q16539	MAPK14	S104	R108Q	108	Missense	distal	4	no	12.483	12.279	EPSD	TCGA;ICGC;COSMIC	5.915	Down-regulation
CMGC_MAPK_p38_MAPK14_ST	Q9NQU5	PAK6	Q16539	MAPK14	S132	D127H	127	Missense	distal	-5	no	11.251	11.389	EPSD	TCGA	5.915	Up-regulation
CMGC_MAPK_p38_MAPK14_ST	Q9NQU5	PAK6	Q16539	MAPK14	S132	L130F	130	Missense	proximal	-2	no	11.251	11.418	EPSD	TCGA;ICGC;COSMIC	5.915	Up-regulation
CMGC_MAPK_p38_MAPK14_ST	Q9NQU5	PAK6	Q16539	MAPK14	S135	L130F	130	Missense	distal	-5	no	6.300	6.356	EPSD	TCGA;ICGC;COSMIC	5.915	Up-regulation
CMGC_MAPK_p38_MAPK14_ST	Q9NQU5	PAK6	Q16539	MAPK14	S165	G172E	172	Missense	distal	7	no	8.810	9.171	PhosphoSitePlus	TCGA;ICGC;COSMIC	5.915	Up-regulation
CMGC_MAPK_p38_MAPK14_ST	Q9NQU5	PAK6	Q16539	MAPK14	S207	R214S	214	Missense	distal	7	no	9.271	9.237	EPSD	TCGA;ICGC	5.915	Down-regulation
CMGC_MAPK_p38_MAPK14_ST	Q9NQU5	PAK6	Q16539	MAPK14	S246	R252W	252	Missense	distal	6	no	15.109	14.846	EPSD	TCGA	5.915	Down-regulation
CMGC_MAPK_p38_MAPK14_ST	Q9NQU5	PAK6	Q16539	MAPK14	S248	R252W	252	Missense	distal	4	no	11.306	10.031	EPSD	TCGA	5.915	Down-regulation
CMGC_MAPK_p38_MAPK14_ST	Q9NQU5	PAK6	Q16539	MAPK14	S248	S254I	254	Missense	distal	6	no	11.306	11.095	EPSD	TCGA;ICGC;COSMIC	5.915	Down-regulation
CMGC_MAPK_p38_MAPK14_ST	Q9NQU5	PAK6	Q16539	MAPK14	T317	P320S	320	Missense	distal	3	no	6.360	6.320	EPSD	TCGA;ICGC;COSMIC	5.915	Down-regulation
CMGC_MAPK_p38_MAPK14_ST	Q9NQU5	PAK6	Q16539	MAPK14	T317	S324L	324	Missense	distal	7	no	6.360	5.975	EPSD	TCGA;ICGC;COSMIC	5.915	Down-regulation
CMGC_MAPK_p38_MAPK14_ST	Q9NQU5	PAK6	Q16539	MAPK14	S319	P320S	320	Missense	proximal	1	no	10.984	3.700	EPSD	TCGA;ICGC;COSMIC	5.915	Loss
CMGC_MAPK_p38_MAPK14_ST	Q9NQU5	PAK6	Q16539	MAPK14	S319	S324L	324	Missense	distal	5	no	10.984	10.036	EPSD	TCGA;ICGC;COSMIC	5.915	Down-regulation
CMGC_MAPK_p38_MAPK14_ST	Q9NQU5	PAK6	Q16539	MAPK14	S328	R334H	334	Missense	distal	6	no	10.654	10.546	EPSD	TCGA;ICGC;COSMIC;GDSC;CCLE	5.915	Down-regulation
CMGC_MAPK_p38_MAPK14_ST	Q9NQU5	PAK6	Q16539	MAPK14	S328	P329L	329	Missense	proximal	1	no	10.654	2.603	EPSD	TCGA;ICGC;COSMIC	5.915	Loss
CMGC_MAPK_p38_MAPK14_ST	Q9NQU5	PAK6	Q16539	MAPK14	S328	S324L	324	Missense	distal	-4	no	10.654	11.253	EPSD	TCGA;ICGC;COSMIC	5.915	Up-regulation
CMGC_MAPK_p38_MAPK14_ST	Q9NQU5	PAK6	Q16539	MAPK14	S328	L333P	333	Missense	distal	5	no	10.654	11.151	EPSD	TCGA;ICGC	5.915	Up-regulation
CMGC_MAPK_p38_MAPK14_ST	Q9NQU5	PAK6	Q16539	MAPK14	S347	G350E	350	Missense	distal	3	no	11.402	11.356	EPSD	TCGA;ICGC;COSMIC	5.915	Down-regulation
CMGC_MAPK_p38_MAPK14_ST	Q9NQU5	PAK6	Q16539	MAPK14	S347	R353C	353	Missense	distal	6	no	11.402	11.127	EPSD	TCGA;ICGC;COSMIC	5.915	Down-regulation
CMGC_MAPK_p38_MAPK14_ST	Q9NQU5	PAK6	Q16539	MAPK14	S347	R353H	353	Missense	distal	6	no	11.402	11.294	EPSD	TCGA;ICGC;COSMIC	5.915	Down-regulation
CMGC_MAPK_p38_MAPK14_ST	Q9NQU5	PAK6	Q16539	MAPK14	S351	G350E	350	Missense	proximal	-1	no	8.820	8.519	EPSD	TCGA;ICGC;COSMIC	5.915	Down-regulation
CMGC_MAPK_p38_MAPK14_ST	Q9NQU5	PAK6	Q16539	MAPK14	S351	R353C	353	Missense	proximal	2	no	8.820	8.552	EPSD	TCGA;ICGC;COSMIC	5.915	Down-regulation
CMGC_MAPK_p38_MAPK14_ST	Q9NQU5	PAK6	Q16539	MAPK14	S351	R353H	353	Missense	proximal	2	no	8.820	8.437	EPSD	TCGA;ICGC;COSMIC	5.915	Down-regulation
CMGC_MAPK_p38_MAPK14_ST	Q9NQU5	PAK6	Q16539	MAPK14	T354	G350E	350	Missense	distal	-4	no	6.255	5.959	EPSD	TCGA;ICGC;COSMIC	5.915	Down-regulation
CMGC_MAPK_p38_MAPK14_ST	Q9NQU5	PAK6	Q16539	MAPK14	T354	R353C	353	Missense	proximal	-1	no	6.255	6.519	EPSD	TCGA;ICGC;COSMIC	5.915	Up-regulation
CMGC_MAPK_p38_MAPK14_ST	Q9NQU5	PAK6	Q16539	MAPK14	T354	S360N	360	Missense	distal	6	no	6.255	6.235	EPSD	TCGA;ICGC;COSMIC	5.915	Down-regulation
CMGC_MAPK_p38_MAPK14_ST	Q9NQU5	PAK6	Q16539	MAPK14	T354	R353H	353	Missense	proximal	-1	no	6.255	6.411	EPSD	TCGA;ICGC;COSMIC	5.915	Up-regulation
CMGC_MAPK_p38_MAPK14_ST	Q9NQU5	PAK6	Q16539	MAPK14	S616	R614Q	614	Missense	proximal	-2	no	10.103	9.776	EPSD	TCGA;ICGC;COSMIC;GDSC;CCLE	5.915	Down-regulation
CMGC_MAPK_p38_MAPK14_ST	P00533	EGFR	Q16539	MAPK14	S227	R222C	222	Missense	distal	-5	no	10.174	10.656	EPSD	TCGA;COSMIC	5.915	Up-regulation
CMGC_MAPK_p38_MAPK14_ST	P00533	EGFR	Q16539	MAPK14	S227	S229C	229	Missense	proximal	2	no	10.174	9.761	EPSD	TCGA;COSMIC	5.915	Down-regulation
CMGC_MAPK_p38_MAPK14_ST	P00533	EGFR	Q16539	MAPK14	S227	C223Y	223	Missense	distal	-4	no	10.174	9.708	EPSD	TCGA;COSMIC	5.915	Down-regulation
CMGC_MAPK_p38_MAPK14_ST	P00533	EGFR	Q16539	MAPK14	S227	R222L	222	Missense	distal	-5	no	10.174	10.684	EPSD	TCGA;COSMIC	5.915	Up-regulation
CMGC_MAPK_p38_MAPK14_ST	P00533	EGFR	Q16539	MAPK14	S227	S227F	227	Missense	central	0	yes	10.174	0.000	EPSD	TCGA;COSMIC	5.915	Loss
CMGC_MAPK_p38_MAPK14_ST	P00533	EGFR	Q16539	MAPK14	S227	P228L	228	Missense	proximal	1	no	10.174	2.123	EPSD	TCGA;COSMIC	5.915	Loss
CMGC_MAPK_p38_MAPK14_ST	P00533	EGFR	Q16539	MAPK14	S227	N234S	234	Missense	distal	7	no	10.174	10.473	EPSD	TCGA;COSMIC	5.915	Up-regulation
CMGC_MAPK_p38_MAPK14_ST	P00533	EGFR	Q16539	MAPK14	S227	R224H	224	Missense	distal	-3	no	10.174	8.420	EPSD	TCGA;COSMIC	5.915	Down-regulation
CMGC_MAPK_p38_MAPK14_ST	P00533	EGFR	Q16539	MAPK14	S511	P512S	512	Missense	proximal	1	no	8.922	1.638	EPSD	TCGA;COSMIC	5.915	Loss
CMGC_MAPK_p38_MAPK14_ST	P00533	EGFR	Q16539	MAPK14	T693	P699L	699	Missense	distal	6	no	14.877	14.738	EPSD;PhosphoSitePlus	TCGA;COSMIC	5.915	Down-regulation
CMGC_MAPK_p38_MAPK14_ST	P00533	EGFR	Q16539	MAPK14	S752	I759N	759	Missense	distal	7	no	11.766	12.200	EPSD	TCGA;COSMIC	5.915	Up-regulation
CMGC_MAPK_p38_MAPK14_ST	P00533	EGFR	Q16539	MAPK14	S752	K754E	754	Missense	proximal	2	no	11.766	12.080	EPSD	TCGA;COSMIC	5.915	Up-regulation
CMGC_MAPK_p38_MAPK14_ST	P00533	EGFR	Q16539	MAPK14	S752	K754I	754	Missense	proximal	2	no	11.766	11.636	EPSD	TCGA;COSMIC	5.915	Down-regulation
CMGC_MAPK_p38_MAPK14_ST	P00533	EGFR	Q16539	MAPK14	S752	P753L	753	Missense	proximal	1	no	11.766	3.715	EPSD	TCGA;COSMIC	5.915	Loss
CMGC_MAPK_p38_MAPK14_ST	P00533	EGFR	Q16539	MAPK14	S752	P753S	753	Missense	proximal	1	no	11.766	4.482	EPSD	TCGA;COSMIC;GDSC;CCLE	5.915	Loss
CMGC_MAPK_p38_MAPK14_ST	P00533	EGFR	Q16539	MAPK14	S925	E928V	928	Missense	distal	3	no	6.152	6.198	EPSD	TCGA;COSMIC	5.915	Up-regulation
CMGC_MAPK_p38_MAPK14_ST	P00533	EGFR	Q16539	MAPK14	S925	S921R	921	Missense	distal	-4	no	6.152	6.163	EPSD	TCGA;COSMIC	5.915	Up-regulation
CMGC_MAPK_p38_MAPK14_ST	P00533	EGFR	Q16539	MAPK14	S925	E922K	922	Missense	distal	-3	no	6.152	5.759	EPSD	TCGA;COSMIC	5.915	Loss
CMGC_MAPK_p38_MAPK14_ST	P00533	EGFR	Q16539	MAPK14	S925	A920S	920	Missense	distal	-5	no	6.152	6.040	EPSD	TCGA;COSMIC	5.915	Down-regulation
CMGC_MAPK_p38_MAPK14_ST	P00533	EGFR	Q16539	MAPK14	S991	F997V	997	Missense	distal	6	no	10.756	10.872	EPSD	TCGA;COSMIC	5.915	Up-regulation
CMGC_MAPK_p38_MAPK14_ST	P00533	EGFR	Q16539	MAPK14	T993	F997V	997	Missense	distal	4	no	5.643	6.478	EPSD	TCGA;COSMIC	5.915	Gain
CMGC_MAPK_p38_MAPK14_ST	P00533	EGFR	Q16539	MAPK14	S1026	T1032S	1032	Missense	distal	6	no	10.355	10.317	EPSD	TCGA;COSMIC	5.915	Down-regulation
CMGC_MAPK_p38_MAPK14_ST	P00533	EGFR	Q16539	MAPK14	S1026	P1019L	1019	Missense	distal	-7	no	10.355	10.162	EPSD	TCGA;COSMIC	5.915	Down-regulation
CMGC_MAPK_p38_MAPK14_ST	P00533	EGFR	Q16539	MAPK14	S1026	R1031Q	1031	Missense	distal	5	no	10.355	10.006	EPSD	TCGA;COSMIC	5.915	Down-regulation
CMGC_MAPK_p38_MAPK14_ST	P00533	EGFR	Q16539	MAPK14	S1028	T1032S	1032	Missense	distal	4	no	8.189	8.451	EPSD	TCGA;COSMIC	5.915	Up-regulation
CMGC_MAPK_p38_MAPK14_ST	P00533	EGFR	Q16539	MAPK14	S1028	R1031Q	1031	Missense	distal	3	no	8.189	8.230	EPSD	TCGA;COSMIC	5.915	Up-regulation
CMGC_MAPK_p38_MAPK14_ST	P00533	EGFR	Q16539	MAPK14	T1032	R1031Q	1031	Missense	proximal	-1	no	11.989	12.077	EPSD	TCGA;COSMIC	5.915	Up-regulation
CMGC_MAPK_p38_MAPK14_ST	P00533	EGFR	Q16539	MAPK14	S1039	T1032S	1032	Missense	distal	-7	no	8.978	9.047	PhosphoSitePlus;EPSD	TCGA;COSMIC	5.915	Up-regulation
CMGC_MAPK_p38_MAPK14_ST	P00533	EGFR	Q16539	MAPK14	S1039	S1042N	1042	Missense	distal	3	no	8.978	9.023	PhosphoSitePlus;EPSD	TCGA;COSMIC	5.915	Up-regulation
CMGC_MAPK_p38_MAPK14_ST	P00533	EGFR	Q16539	MAPK14	S1130	P1123S	1123	Missense	distal	-7	no	6.415	6.502	EPSD	TCGA;ICGC	5.915	Up-regulation
CMGC_MAPK_p38_MAPK14_ST	P00533	EGFR	Q16539	MAPK14	S1153	D1152N	1152	Missense	proximal	-1	no	7.391	7.206	EPSD	TCGA;ICGC;COSMIC	5.915	Down-regulation
CMGC_MAPK_p38_MAPK14_ST	P00533	EGFR	Q16539	MAPK14	S1153	T1150S	1150	Missense	distal	-3	no	7.391	7.709	EPSD	TCGA;ICGC;COSMIC	5.915	Up-regulation
CMGC_MAPK_p38_MAPK14_ST	P00533	EGFR	Q16539	MAPK14	S1153	F1151L	1151	Missense	proximal	-2	no	7.391	7.224	EPSD	TCGA;ICGC;COSMIC	5.915	Down-regulation
CMGC_MAPK_p38_MAPK14_ST	P00533	EGFR	Q16539	MAPK14	S1153	V1147A	1147	Missense	distal	-6	no	7.391	7.879	EPSD	TCGA;ICGC	5.915	Up-regulation
CMGC_MAPK_p38_MAPK14_ST	Q06413	MEF2C	Q16539	MAPK14	S82	H76L	76	Missense	distal	-6	no	7.468	7.317	EPSD	TCGA	5.915	Down-regulation
CMGC_MAPK_p38_MAPK14_ST	Q06413	MEF2C	Q16539	MAPK14	S82	V85M	85	Missense	distal	3	no	7.468	7.463	EPSD	TCGA;ICGC;COSMIC	5.915	Down-regulation
CMGC_MAPK_p38_MAPK14_ST	Q06413	MEF2C	Q16539	MAPK14	S98	A103V	103	Missense	distal	5	no	10.232	10.214	EPSD	TCGA;ICGC	5.915	Down-regulation
CMGC_MAPK_p38_MAPK14_ST	Q06413	MEF2C	Q16539	MAPK14	S98	C96F	96	Missense	proximal	-2	no	10.232	10.643	EPSD	TCGA;ICGC;COSMIC	5.915	Up-regulation
CMGC_MAPK_p38_MAPK14_ST	Q06413	MEF2C	Q16539	MAPK14	S110	A103V	103	Missense	distal	-7	no	11.217	10.398	EPSD	TCGA;ICGC	5.915	Down-regulation
CMGC_MAPK_p38_MAPK14_ST	Q06413	MEF2C	Q16539	MAPK14	S110	S106F	106	Missense	distal	-4	no	11.217	11.921	EPSD	TCGA;ICGC;COSMIC	5.915	Up-regulation
CMGC_MAPK_p38_MAPK14_ST	Q06413	MEF2C	Q16539	MAPK14	S387	S387I	387	Missense	central	0	yes	5.932	0.000	PhosphoSitePlus;EPSD	TCGA;COSMIC	5.915	Loss
CMGC_MAPK_p38_MAPK14_ST	Q06413	MEF2C	Q16539	MAPK14	S428	S429P	429	Missense	proximal	1	no	4.707	11.991	EPSD	TCGA;COSMIC	5.915	Gain
CMGC_MAPK_p38_MAPK14_ST	P42574	CASP3	Q16539	MAPK14	S150	G153E	153	Missense	distal	3	no	7.178	7.132	PhosphoSitePlus	TCGA;ICGC;COSMIC	5.915	Down-regulation
CMGC_MAPK_p38_MAPK14_ST	P42574	CASP3	Q16539	MAPK14	S150	R147C	147	Missense	distal	-3	no	7.178	4.982	PhosphoSitePlus	TCGA;ICGC;COSMIC	5.915	Loss
CMGC_MAPK_p38_MAPK14_ST	Q8NHW3	MAFA	Q16539	MAPK14	S14	A9D	9	Missense	distal	-5	no	9.437	9.948	EPSD	TCGA;ICGC;COSMIC	5.915	Up-regulation
CMGC_MAPK_p38_MAPK14_ST	Q14934	NFATC4	Q16539	MAPK14	S334	R332Q	332	Missense	proximal	-2	no	6.673	6.346	EPSD	TCGA;COSMIC	5.915	Down-regulation
CMGC_MAPK_p38_MAPK14_ST	Q14934	NFATC4	Q16539	MAPK14	S819	G824V	824	Missense	distal	5	no	11.591	11.189	EPSD	TCGA;COSMIC	5.915	Down-regulation
CMGC_MAPK_p38_MAPK14_ST	O43524	FOXO3	Q16539	MAPK14	S294	S299I	299	Missense	distal	5	no	10.128	9.035	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	5.915	Down-regulation
CMGC_MAPK_p38_MAPK14_ST	O43524	FOXO3	Q16539	MAPK14	S294	R298C	298	Missense	distal	4	no	10.128	9.694	EPSD;PhosphoSitePlus	TCGA;ICGC	5.915	Down-regulation
CMGC_MAPK_p38_MAPK14_ST	O43524	FOXO3	Q16539	MAPK14	S294	G293D	293	Missense	proximal	-1	no	10.128	10.172	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	5.915	Up-regulation
CMGC_MAPK_p38_MAPK14_ST	O43524	FOXO3	Q16539	MAPK14	S325	R323L	323	Missense	proximal	-2	no	12.190	11.499	EPSD	TCGA;ICGC;COSMIC	5.915	Down-regulation
CMGC_MAPK_p38_MAPK14_ST	O43524	FOXO3	Q16539	MAPK14	S325	M328I	328	Missense	distal	3	no	12.190	12.249	EPSD	TCGA;ICGC;COSMIC	5.915	Up-regulation
CMGC_MAPK_p38_MAPK14_ST	O43524	FOXO3	Q16539	MAPK14	S344	A341V	341	Missense	distal	-3	no	12.103	10.602	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	5.915	Down-regulation
CMGC_MAPK_p38_MAPK14_ST	O43524	FOXO3	Q16539	MAPK14	S344	D340G	340	Missense	distal	-4	no	12.103	11.607	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	5.915	Down-regulation
CMGC_MAPK_p38_MAPK14_ST	O43524	FOXO3	Q16539	MAPK14	S355	C362F	362	Missense	distal	7	no	13.176	12.871	EPSD	TCGA;ICGC;COSMIC	5.915	Down-regulation
CMGC_MAPK_p38_MAPK14_ST	O43524	FOXO3	Q16539	MAPK14	S402	P397S	397	Missense	distal	-5	no	11.728	11.280	EPSD	TCGA;ICGC;COSMIC	5.915	Down-regulation
CMGC_MAPK_p38_MAPK14_ST	O43524	FOXO3	Q16539	MAPK14	S402	P397L	397	Missense	distal	-5	no	11.728	12.009	EPSD	TCGA;ICGC;COSMIC	5.915	Up-regulation
CMGC_MAPK_p38_MAPK14_ST	O43524	FOXO3	Q16539	MAPK14	S402	S402L	402	Missense	central	0	yes	11.728	0.000	EPSD	TCGA;ICGC;COSMIC	5.915	Loss
CMGC_MAPK_p38_MAPK14_ST	O43524	FOXO3	Q16539	MAPK14	S425	L423M	423	Missense	proximal	-2	no	11.529	12.097	EPSD;PhosphoSitePlus	TCGA;ICGC	5.915	Up-regulation
CMGC_MAPK_p38_MAPK14_ST	O43524	FOXO3	Q16539	MAPK14	S425	S425F	425	Missense	central	0	yes	11.529	0.000	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	5.915	Loss
CMGC_MAPK_p38_MAPK14_ST	O43524	FOXO3	Q16539	MAPK14	S446	Q449H	449	Missense	distal	3	no	7.519	7.550	EPSD	TCGA;ICGC;COSMIC	5.915	Up-regulation
CMGC_MAPK_p38_MAPK14_ST	O43524	FOXO3	Q16539	MAPK14	S574	M580I	580	Missense	distal	6	no	8.988	8.729	EPSD	TCGA;ICGC;COSMIC	5.915	Down-regulation
CMGC_MAPK_p38_MAPK14_ST	O43524	FOXO3	Q16539	MAPK14	S669	A665S	665	Missense	distal	-4	no	8.191	8.151	EPSD	TCGA;ICGC;COSMIC	5.915	Down-regulation
CMGC_MAPK_p38_MAPK14_ST	O43524	FOXO3	Q16539	MAPK14	S669	S669R	669	Missense	central	0	yes	8.191	0.000	EPSD	TCGA;ICGC	5.915	Loss
CMGC_MAPK_p38_MAPK14_ST	P42566	EPS15	Q16539	MAPK14	S140	A134T	134	Missense	distal	-6	no	10.755	11.025	EPSD	TCGA;ICGC	5.915	Up-regulation
CMGC_MAPK_p38_MAPK14_ST	P42566	EPS15	Q16539	MAPK14	S140	L139V	139	Missense	proximal	-1	no	10.755	10.693	EPSD	TCGA;ICGC	5.915	Down-regulation
CMGC_MAPK_p38_MAPK14_ST	P42566	EPS15	Q16539	MAPK14	S221	T217S	217	Missense	distal	-4	no	11.326	11.049	EPSD	TCGA;ICGC;COSMIC	5.915	Down-regulation
CMGC_MAPK_p38_MAPK14_ST	P42566	EPS15	Q16539	MAPK14	T304	S311L	311	Missense	distal	7	no	10.225	9.840	EPSD	TCGA;ICGC;COSMIC	5.915	Down-regulation
CMGC_MAPK_p38_MAPK14_ST	P42566	EPS15	Q16539	MAPK14	T304	H301D	301	Missense	distal	-3	no	10.225	10.477	EPSD	TCGA;ICGC;COSMIC	5.915	Up-regulation
CMGC_MAPK_p38_MAPK14_ST	P42566	EPS15	Q16539	MAPK14	T304	P305A	305	Missense	proximal	1	no	10.225	3.906	EPSD	TCGA;ICGC;COSMIC	5.915	Loss
CMGC_MAPK_p38_MAPK14_ST	P42566	EPS15	Q16539	MAPK14	T304	E306G	306	Missense	proximal	2	no	10.225	10.031	EPSD	TCGA;ICGC;COSMIC	5.915	Down-regulation
CMGC_MAPK_p38_MAPK14_ST	P42566	EPS15	Q16539	MAPK14	S324	S323P	323	Missense	proximal	-1	no	8.909	9.002	EPSD	TCGA;ICGC;COSMIC	5.915	Up-regulation
CMGC_MAPK_p38_MAPK14_ST	P42566	EPS15	Q16539	MAPK14	S324	F329L	329	Missense	distal	5	no	8.909	9.403	EPSD	TCGA;ICGC;COSMIC	5.915	Up-regulation
CMGC_MAPK_p38_MAPK14_ST	P42566	EPS15	Q16539	MAPK14	S330	S323P	323	Missense	distal	-7	no	7.637	7.550	EPSD	TCGA;ICGC;COSMIC	5.915	Down-regulation
CMGC_MAPK_p38_MAPK14_ST	P42566	EPS15	Q16539	MAPK14	S330	F329L	329	Missense	proximal	-1	no	7.637	7.673	EPSD	TCGA;ICGC;COSMIC	5.915	Up-regulation
CMGC_MAPK_p38_MAPK14_ST	P42566	EPS15	Q16539	MAPK14	S330	T337I	337	Missense	distal	7	no	7.637	7.225	EPSD	TCGA;ICGC;COSMIC	5.915	Down-regulation
CMGC_MAPK_p38_MAPK14_ST	P42566	EPS15	Q16539	MAPK14	S558	A560T	560	Missense	proximal	2	no	13.511	13.539	EPSD	TCGA;COSMIC	5.915	Up-regulation
CMGC_MAPK_p38_MAPK14_ST	P42566	EPS15	Q16539	MAPK14	S558	P559Q	559	Missense	proximal	1	no	13.511	6.303	EPSD	TCGA;COSMIC	5.915	Down-regulation
CMGC_MAPK_p38_MAPK14_ST	P42566	EPS15	Q16539	MAPK14	S563	A560T	560	Missense	distal	-3	no	10.221	10.315	EPSD	TCGA;COSMIC	5.915	Up-regulation
CMGC_MAPK_p38_MAPK14_ST	P42566	EPS15	Q16539	MAPK14	S563	P559Q	559	Missense	distal	-4	no	10.221	10.512	EPSD	TCGA;COSMIC	5.915	Up-regulation
CMGC_MAPK_p38_MAPK14_ST	P42566	EPS15	Q16539	MAPK14	S719	A712S	712	Missense	distal	-7	no	6.777	6.664	EPSD	TCGA;COSMIC	5.915	Down-regulation
CMGC_MAPK_p38_MAPK14_ST	P42566	EPS15	Q16539	MAPK14	S719	V714D	714	Missense	distal	-5	no	6.777	6.796	EPSD	TCGA;COSMIC	5.915	Up-regulation
CMGC_MAPK_p38_MAPK14_ST	P42566	EPS15	Q16539	MAPK14	S741	R740H	740	Missense	proximal	-1	no	6.487	6.642	EPSD	TCGA;COSMIC	5.915	Up-regulation
CMGC_MAPK_p38_MAPK14_ST	P42566	EPS15	Q16539	MAPK14	S741	V747A	747	Missense	distal	6	no	6.487	6.782	EPSD	TCGA	5.915	Up-regulation
CMGC_MAPK_p38_MAPK14_ST	P42566	EPS15	Q16539	MAPK14	S744	R740H	740	Missense	distal	-4	no	7.117	7.328	EPSD	TCGA;COSMIC	5.915	Up-regulation
CMGC_MAPK_p38_MAPK14_ST	P42566	EPS15	Q16539	MAPK14	S744	V747A	747	Missense	distal	3	no	7.117	7.089	EPSD	TCGA	5.915	Down-regulation
CMGC_MAPK_p38_MAPK14_ST	P42566	EPS15	Q16539	MAPK14	T777	G776R	776	Missense	proximal	-1	no	6.319	5.999	EPSD	TCGA;COSMIC	5.915	Down-regulation
CMGC_MAPK_p38_MAPK14_ST	P42566	EPS15	Q16539	MAPK14	T777	K774N	774	Missense	distal	-3	no	6.319	6.347	EPSD	TCGA;COSMIC	5.915	Up-regulation
CMGC_MAPK_p38_MAPK14_ST	P42566	EPS15	Q16539	MAPK14	T777	A770S	770	Missense	distal	-7	no	6.319	6.206	EPSD	TCGA;COSMIC	5.915	Down-regulation
CMGC_MAPK_p38_MAPK14_ST	P42566	EPS15	Q16539	MAPK14	T777	T777N	777	Missense	central	0	yes	6.319	0.000	EPSD	TCGA;COSMIC	5.915	Loss
CMGC_MAPK_p38_MAPK14_ST	P42566	EPS15	Q16539	MAPK14	S796	D798E	798	Missense	proximal	2	no	9.943	10.394	PhosphoSitePlus	TCGA;COSMIC	5.915	Up-regulation
CMGC_MAPK_p38_MAPK14_ST	P42566	EPS15	Q16539	MAPK14	S796	S796Y	796	Missense	central	0	yes	9.943	0.000	PhosphoSitePlus	TCGA;COSMIC	5.915	Loss
CMGC_MAPK_p38_MAPK14_ST	P42566	EPS15	Q16539	MAPK14	S796	K793N	793	Missense	distal	-3	no	9.943	9.971	PhosphoSitePlus	TCGA;COSMIC	5.915	Up-regulation
CMGC_MAPK_p38_MAPK14_ST	O60381	HBP1	Q16539	MAPK14	S135	S135C	135	Missense	central	0	yes	10.736	0.000	EPSD	TCGA;ICGC;COSMIC	5.915	Loss
CMGC_MAPK_p38_MAPK14_ST	O60381	HBP1	Q16539	MAPK14	S157	S159L	159	Missense	proximal	2	no	8.293	7.804	EPSD	TCGA;ICGC;COSMIC	5.915	Down-regulation
CMGC_MAPK_p38_MAPK14_ST	O60381	HBP1	Q16539	MAPK14	S157	R151H	151	Missense	distal	-6	no	8.293	7.330	EPSD	TCGA;ICGC;COSMIC;CCLE	5.915	Down-regulation
CMGC_MAPK_p38_MAPK14_ST	O60381	HBP1	Q16539	MAPK14	S157	S158F	158	Missense	proximal	1	no	8.293	9.573	EPSD	TCGA;ICGC;COSMIC;GDSC;CCLE	5.915	Up-regulation
CMGC_MAPK_p38_MAPK14_ST	O60381	HBP1	Q16539	MAPK14	S402	S409T	409	Missense	distal	7	no	9.658	9.337	PhosphoSitePlus	TCGA;ICGC;COSMIC	5.915	Down-regulation
CMGC_MAPK_p38_MAPK14_ST	Q8IW41	MAPKAPK5	Q16539	MAPK14	T182	T182P	182	Missense	central	0	yes	9.718	0.000	PhosphoSitePlus	TCGA;ICGC;COSMIC	5.915	Loss
CMGC_MAPK_p38_MAPK14_ST	Q8IW41	MAPKAPK5	Q16539	MAPK14	T182	G178S	178	Missense	distal	-4	no	9.718	9.720	PhosphoSitePlus	TCGA;ICGC;COSMIC	5.915	Up-regulation
CMGC_MAPK_p38_MAPK14_ST	Q8IW41	MAPKAPK5	Q16539	MAPK14	T186	T182P	182	Missense	distal	-4	no	12.505	12.316	EPSD	TCGA;ICGC;COSMIC	5.915	Down-regulation
CMGC_MAPK_p38_MAPK14_ST	Q8IW41	MAPKAPK5	Q16539	MAPK14	S212	T214M	214	Missense	proximal	2	no	11.797	11.778	EPSD	TCGA;ICGC;COSMIC	5.915	Down-regulation
CMGC_MAPK_p38_MAPK14_ST	Q8IW41	MAPKAPK5	Q16539	MAPK14	T214	T214M	214	Missense	central	0	yes	9.025	0.000	EPSD	TCGA;ICGC;COSMIC	5.915	Loss
CMGC_MAPK_p38_MAPK14_ST	Q8IW41	MAPKAPK5	Q16539	MAPK14	T217	T214M	214	Missense	distal	-3	no	6.492	5.386	EPSD	TCGA;ICGC;COSMIC	5.915	Loss
CMGC_MAPK_p38_MAPK14_ST	P42677	RPS27	Q16539	MAPK14	S11	E14A	14	Missense	distal	3	no	11.304	11.322	EPSD	TCGA;ICGC;COSMIC	5.915	Up-regulation
CMGC_MAPK_p38_MAPK14_ST	P42677	RPS27	Q16539	MAPK14	S11	D6N	6	Missense	distal	-5	no	11.304	11.144	EPSD	TCGA;ICGC;COSMIC	5.915	Down-regulation
CMGC_MAPK_p38_MAPK14_ST	P42677	RPS27	Q16539	MAPK14	S11	S11F	11	Missense	central	0	yes	11.304	0.000	EPSD	TCGA;ICGC;COSMIC	5.915	Loss
CMGC_MAPK_p38_MAPK14_ST	P42677	RPS27	Q16539	MAPK14	S27	F32V	32	Missense	distal	5	no	10.240	11.024	PhosphoSitePlus	TCGA;ICGC;COSMIC	5.915	Up-regulation
CMGC_MAPK_p38_MAPK14_ST	P42677	RPS27	Q16539	MAPK14	T74	S78F	78	Missense	distal	4	no	6.029	4.455	EPSD	TCGA;ICGC;COSMIC	5.915	Loss
CMGC_MAPK_p38_MAPK14_ST	P42677	RPS27	Q16539	MAPK14	S78	S78F	78	Missense	central	0	yes	8.689	0.000	EPSD	TCGA;ICGC;COSMIC	5.915	Loss
CMGC_MAPK_p38_MAPK14_ST	P17302	GJA1	Q16539	MAPK14	S255	G261V	261	Missense	distal	6	no	9.570	9.208	EPSD	TCGA;ICGC;COSMIC	5.915	Down-regulation
CMGC_MAPK_p38_MAPK14_ST	P17302	GJA1	Q16539	MAPK14	S273	A276T	276	Missense	distal	3	no	9.914	9.913	EPSD	TCGA;ICGC;COSMIC	5.915	Down-regulation
CMGC_MAPK_p38_MAPK14_ST	P17302	GJA1	Q16539	MAPK14	S273	T275I	275	Missense	proximal	2	no	9.914	9.670	EPSD	TCGA;ICGC;COSMIC	5.915	Down-regulation
CMGC_MAPK_p38_MAPK14_ST	P17302	GJA1	Q16539	MAPK14	S273	F268S	268	Missense	distal	-5	no	9.914	9.129	EPSD	TCGA;ICGC;COSMIC	5.915	Down-regulation
CMGC_MAPK_p38_MAPK14_ST	P17302	GJA1	Q16539	MAPK14	T275	A276T	276	Missense	proximal	1	no	7.352	6.217	EPSD	TCGA;ICGC;COSMIC	5.915	Down-regulation
CMGC_MAPK_p38_MAPK14_ST	P17302	GJA1	Q16539	MAPK14	T275	T275I	275	Missense	central	0	yes	7.352	0.000	EPSD	TCGA;ICGC;COSMIC	5.915	Loss
CMGC_MAPK_p38_MAPK14_ST	P17302	GJA1	Q16539	MAPK14	T275	F268S	268	Missense	distal	-7	no	7.352	8.098	EPSD	TCGA;ICGC;COSMIC	5.915	Up-regulation
CMGC_MAPK_p38_MAPK14_ST	P17302	GJA1	Q16539	MAPK14	S279	A276T	276	Missense	distal	-3	no	14.969	15.063	PhosphoSitePlus;EPSD	TCGA;ICGC;COSMIC	5.915	Up-regulation
CMGC_MAPK_p38_MAPK14_ST	P17302	GJA1	Q16539	MAPK14	S279	T275I	275	Missense	distal	-4	no	14.969	14.859	PhosphoSitePlus;EPSD	TCGA;ICGC;COSMIC	5.915	Down-regulation
CMGC_MAPK_p38_MAPK14_ST	P17302	GJA1	Q16539	MAPK14	S282	A276T	276	Missense	distal	-6	no	13.285	13.554	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	5.915	Up-regulation
CMGC_MAPK_p38_MAPK14_ST	P17302	GJA1	Q16539	MAPK14	S282	T275I	275	Missense	distal	-7	no	13.285	12.933	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	5.915	Down-regulation
CMGC_MAPK_p38_MAPK14_ST	P17302	GJA1	Q16539	MAPK14	S314	Q317R	317	Missense	distal	3	no	6.095	6.054	EPSD	TCGA;ICGC;COSMIC	5.915	Down-regulation
CMGC_MAPK_p38_MAPK14_ST	P17302	GJA1	Q16539	MAPK14	S314	S314R	314	Missense	central	0	yes	6.095	0.000	EPSD	TCGA;ICGC;COSMIC	5.915	Loss
CMGC_MAPK_p38_MAPK14_ST	P17302	GJA1	Q16539	MAPK14	S314	R319Q	319	Missense	distal	5	no	6.095	5.746	EPSD	TCGA;ICGC;COSMIC	5.915	Loss
CMGC_MAPK_p38_MAPK14_ST	P17302	GJA1	Q16539	MAPK14	S364	V359L	359	Missense	distal	-5	no	6.602	6.727	EPSD	TCGA;ICGC;COSMIC	5.915	Up-regulation
CMGC_MAPK_p38_MAPK14_ST	P17302	GJA1	Q16539	MAPK14	S364	S369N	369	Missense	distal	5	no	6.602	6.266	EPSD	TCGA;ICGC;COSMIC	5.915	Down-regulation
CMGC_MAPK_p38_MAPK14_ST	P17302	GJA1	Q16539	MAPK14	S368	S369N	369	Missense	proximal	1	no	7.255	6.735	EPSD	TCGA;ICGC;COSMIC	5.915	Down-regulation
CMGC_MAPK_p38_MAPK14_ST	P17302	GJA1	Q16539	MAPK14	S372	S369N	369	Missense	distal	-3	no	7.971	6.824	EPSD	TCGA;ICGC;COSMIC	5.915	Down-regulation
CMGC_MAPK_p38_MAPK14_ST	O43464	HTRA2	Q16539	MAPK14	T54	R60W	60	Missense	distal	6	no	9.510	9.246	EPSD	TCGA;ICGC;COSMIC;CCLE	5.915	Down-regulation
CMGC_MAPK_p38_MAPK14_ST	O43464	HTRA2	Q16539	MAPK14	S96	T90I	90	Missense	distal	-6	no	7.175	6.153	EPSD	TCGA;ICGC;COSMIC	5.915	Down-regulation
CMGC_MAPK_p38_MAPK14_ST	O43464	HTRA2	Q16539	MAPK14	T221	V219L	219	Missense	proximal	-2	no	6.807	6.505	EPSD	TCGA;ICGC;COSMIC	5.915	Down-regulation
CMGC_MAPK_p38_MAPK14_ST	O43464	HTRA2	Q16539	MAPK14	T221	A222V	222	Missense	proximal	1	no	6.807	3.848	EPSD	TCGA;ICGC;COSMIC	5.915	Loss
CMGC_MAPK_p38_MAPK14_ST	P41235	HNF4A	Q16539	MAPK14	S167	V160F	160	Missense	distal	-7	no	7.662	7.621	PhosphoSitePlus	TCGA	5.915	Down-regulation
CMGC_MAPK_p38_MAPK14_ST	P41235	HNF4A	Q16539	MAPK14	S167	S170C	170	Missense	distal	3	no	7.662	7.746	PhosphoSitePlus	TCGA;COSMIC	5.915	Up-regulation
CMGC_MAPK_p38_MAPK14_ST	P41235	HNF4A	Q16539	MAPK14	S167	G174S	174	Missense	distal	7	no	7.662	7.805	PhosphoSitePlus	TCGA;ICGC;COSMIC	5.915	Up-regulation
CMGC_MAPK_p38_MAPK14_ST	P41235	HNF4A	Q16539	MAPK14	S313	S313F	313	Missense	central	0	yes	7.604	0.000	EPSD	TCGA;ICGC;COSMIC	5.915	Loss
CMGC_MAPK_p38_MAPK14_ST	P41235	HNF4A	Q16539	MAPK14	S378	D381N	381	Missense	distal	3	no	11.760	11.754	EPSD	TCGA;ICGC;COSMIC	5.915	Down-regulation
CMGC_MAPK_p38_MAPK14_ST	P41235	HNF4A	Q16539	MAPK14	S378	A382S	382	Missense	distal	4	no	11.760	12.066	EPSD	TCGA;ICGC;COSMIC	5.915	Up-regulation
CMGC_MAPK_p38_MAPK14_ST	P41235	HNF4A	Q16539	MAPK14	S378	H384N	384	Missense	distal	6	no	11.760	11.847	EPSD	TCGA;COSMIC	5.915	Up-regulation
CMGC_MAPK_p38_MAPK14_ST	P41235	HNF4A	Q16539	MAPK14	S378	G377E	377	Missense	proximal	-1	no	11.760	11.460	EPSD	TCGA;ICGC;COSMIC	5.915	Down-regulation
CMGC_MAPK_p38_MAPK14_ST	P41235	HNF4A	Q16539	MAPK14	S378	S380N	380	Missense	proximal	2	no	11.760	11.504	EPSD	TCGA;COSMIC	5.915	Down-regulation
CMGC_MAPK_p38_MAPK14_ST	P41235	HNF4A	Q16539	MAPK14	S378	G376R	376	Missense	proximal	-2	no	11.760	12.010	EPSD	TCGA;ICGC;COSMIC	5.915	Up-regulation
CMGC_MAPK_p38_MAPK14_ST	P41235	HNF4A	Q16539	MAPK14	S378	S380G	380	Missense	proximal	2	no	11.760	11.531	EPSD	TCGA;COSMIC	5.915	Down-regulation
CMGC_MAPK_p38_MAPK14_ST	P41235	HNF4A	Q16539	MAPK14	S378	D381V	381	Missense	distal	3	no	11.760	11.751	EPSD	TCGA;ICGC;COSMIC	5.915	Down-regulation
CMGC_MAPK_p38_MAPK14_ST	P41235	HNF4A	Q16539	MAPK14	T429	P433S	433	Missense	distal	4	no	8.288	8.727	EPSD	TCGA;COSMIC	5.915	Up-regulation
CMGC_MAPK_p38_MAPK14_ST	P41235	HNF4A	Q16539	MAPK14	T429	G425R	425	Missense	distal	-4	no	8.288	8.301	EPSD	TCGA;COSMIC	5.915	Up-regulation
CMGC_MAPK_p38_MAPK14_ST	P41235	HNF4A	Q16539	MAPK14	T429	R422Q	422	Missense	distal	-7	no	8.288	8.194	EPSD	TCGA;COSMIC	5.915	Down-regulation
CMGC_MAPK_p38_MAPK14_ST	P41235	HNF4A	Q16539	MAPK14	T429	T432I	432	Missense	distal	3	no	8.288	8.370	EPSD	TCGA;COSMIC	5.915	Up-regulation
CMGC_MAPK_p38_MAPK14_ST	P41235	HNF4A	Q16539	MAPK14	T432	P433S	433	Missense	proximal	1	no	10.565	3.282	EPSD	TCGA;COSMIC	5.915	Loss
CMGC_MAPK_p38_MAPK14_ST	P41235	HNF4A	Q16539	MAPK14	T432	G425R	425	Missense	distal	-7	no	10.565	10.464	EPSD	TCGA;COSMIC	5.915	Down-regulation
CMGC_MAPK_p38_MAPK14_ST	P41235	HNF4A	Q16539	MAPK14	T432	T432I	432	Missense	central	0	yes	10.565	0.000	EPSD	TCGA;COSMIC	5.915	Loss
CMGC_MAPK_p38_MAPK14_ST	P41235	HNF4A	Q16539	MAPK14	S436	S443Y	443	Missense	distal	7	no	10.226	10.269	EPSD	TCGA;COSMIC	5.915	Up-regulation
CMGC_MAPK_p38_MAPK14_ST	P41235	HNF4A	Q16539	MAPK14	S436	P433S	433	Missense	distal	-3	no	10.226	10.990	EPSD	TCGA;COSMIC	5.915	Up-regulation
CMGC_MAPK_p38_MAPK14_ST	P41235	HNF4A	Q16539	MAPK14	S436	G442E	442	Missense	distal	6	no	10.226	10.185	EPSD	TCGA;COSMIC	5.915	Down-regulation
CMGC_MAPK_p38_MAPK14_ST	P41235	HNF4A	Q16539	MAPK14	S436	T432I	432	Missense	distal	-4	no	10.226	10.116	EPSD	TCGA;COSMIC	5.915	Down-regulation
CMGC_MAPK_p38_MAPK14_ST	P41235	HNF4A	Q16539	MAPK14	S461	V457I	457	Missense	distal	-4	no	6.182	6.026	EPSD	TCGA;COSMIC	5.915	Down-regulation
CMGC_MAPK_p38_MAPK14_ST	P41235	HNF4A	Q16539	MAPK14	S461	T467A	467	Missense	distal	6	no	6.182	6.199	EPSD	TCGA	5.915	Up-regulation
CMGC_MAPK_p38_MAPK14_ST	P05787	KRT8	Q16539	MAPK14	S35	S37F	37	Missense	proximal	2	no	6.190	5.524	EPSD	TCGA;ICGC;COSMIC	5.915	Loss
CMGC_MAPK_p38_MAPK14_ST	P05787	KRT8	Q16539	MAPK14	S37	S37F	37	Missense	central	0	yes	7.166	0.000	EPSD	TCGA;ICGC;COSMIC	5.915	Loss
CMGC_MAPK_p38_MAPK14_ST	P05787	KRT8	Q16539	MAPK14	S43	S37F	37	Missense	distal	-6	no	6.445	4.681	EPSD	TCGA;ICGC;COSMIC	5.915	Loss
CMGC_MAPK_p38_MAPK14_ST	P05787	KRT8	Q16539	MAPK14	S432	S438G	438	Missense	distal	6	no	8.643	8.764	EPSD	TCGA;COSMIC	5.915	Up-regulation
CMGC_MAPK_p38_MAPK14_ST	P11362	FGFR1	Q16539	MAPK14	T454	S461F	461	Missense	distal	7	no	14.298	13.428	EPSD	TCGA;COSMIC	5.915	Down-regulation
CMGC_MAPK_p38_MAPK14_ST	O15151	MDM4	Q16539	MAPK14	S20	Q26E	26	Missense	distal	6	no	7.768	7.836	EPSD	TCGA;ICGC;COSMIC	5.915	Up-regulation
CMGC_MAPK_p38_MAPK14_ST	O15151	MDM4	Q16539	MAPK14	S20	R18S	18	Missense	proximal	-2	no	7.768	7.967	EPSD	TCGA;ICGC	5.915	Up-regulation
CMGC_MAPK_p38_MAPK14_ST	O15151	MDM4	Q16539	MAPK14	S96	D100N	100	Missense	distal	4	no	8.556	9.209	EPSD	TCGA;ICGC;COSMIC	5.915	Up-regulation
CMGC_MAPK_p38_MAPK14_ST	O15151	MDM4	Q16539	MAPK14	T263	Q262H	262	Missense	proximal	-1	no	6.163	6.230	EPSD	TCGA;ICGC;COSMIC	5.915	Up-regulation
CMGC_MAPK_p38_MAPK14_ST	O15151	MDM4	Q16539	MAPK14	T263	A257V	257	Missense	distal	-6	no	6.163	5.675	EPSD	TCGA;ICGC;COSMIC	5.915	Loss
CMGC_MAPK_p38_MAPK14_ST	O15151	MDM4	Q16539	MAPK14	T263	T260I	260	Missense	distal	-3	no	6.163	4.409	EPSD	TCGA;ICGC;COSMIC	5.915	Loss
CMGC_MAPK_p38_MAPK14_ST	O15151	MDM4	Q16539	MAPK14	S314	K317N	317	Missense	distal	3	no	11.158	11.159	PhosphoSitePlus	TCGA;ICGC;COSMIC	5.915	Up-regulation
CMGC_MAPK_p38_MAPK14_ST	O15151	MDM4	Q16539	MAPK14	S314	C309S	309	Missense	distal	-5	no	11.158	10.457	PhosphoSitePlus	TCGA;COSMIC	5.915	Down-regulation
CMGC_MAPK_p38_MAPK14_ST	O15151	MDM4	Q16539	MAPK14	S314	E308A	308	Missense	distal	-6	no	11.158	10.786	PhosphoSitePlus	TCGA;ICGC;COSMIC	5.915	Down-regulation
CMGC_MAPK_p38_MAPK14_ST	Q99626	CDX2	Q16539	MAPK14	S60	P61S	61	Missense	proximal	1	no	12.446	5.163	EPSD	TCGA;ICGC;COSMIC	5.915	Loss
CMGC_MAPK_p38_MAPK14_ST	Q99626	CDX2	Q16539	MAPK14	S179	L177I	177	Missense	proximal	-2	no	5.659	6.221	EPSD	TCGA;ICGC	5.915	Gain
CMGC_MAPK_p38_MAPK14_ST	Q99626	CDX2	Q16539	MAPK14	S283	L288V	288	Missense	distal	5	no	10.883	11.174	PhosphoSitePlus	TCGA;ICGC;COSMIC	5.915	Up-regulation
CMGC_MAPK_p38_MAPK14_ST	Q99626	CDX2	Q16539	MAPK14	S286	L288V	288	Missense	proximal	2	no	8.061	8.122	EPSD	TCGA;ICGC;COSMIC	5.915	Up-regulation
CMGC_MAPK_p38_MAPK14_ST	Q15075	EEA1	Q16539	MAPK14	T25	P26L	26	Missense	proximal	1	no	12.865	4.814	EPSD	TCGA;ICGC;COSMIC	5.915	Loss
CMGC_MAPK_p38_MAPK14_ST	Q15075	EEA1	Q16539	MAPK14	T25	V32I	32	Missense	distal	7	no	12.865	12.218	EPSD	TCGA;ICGC	5.915	Down-regulation
CMGC_MAPK_p38_MAPK14_ST	Q15075	EEA1	Q16539	MAPK14	S354	R352T	352	Missense	proximal	-2	no	7.011	6.979	EPSD	TCGA;ICGC;COSMIC	5.915	Down-regulation
CMGC_MAPK_p38_MAPK14_ST	Q15075	EEA1	Q16539	MAPK14	S354	R352I	352	Missense	proximal	-2	no	7.011	6.881	EPSD	TCGA;ICGC	5.915	Down-regulation
CMGC_MAPK_p38_MAPK14_ST	Q15075	EEA1	Q16539	MAPK14	S1265	R1262Q	1262	Missense	distal	-3	no	6.316	4.537	EPSD	TCGA;ICGC;COSMIC	5.915	Loss
CMGC_MAPK_p38_MAPK14_ST	Q15075	EEA1	Q16539	MAPK14	S1366	V1367A	1367	Missense	proximal	1	no	4.634	7.593	EPSD	TCGA;ICGC;COSMIC	5.915	Gain
CMGC_MAPK_p38_MAPK14_ST	Q15075	EEA1	Q16539	MAPK14	S1386	I1380M	1380	Missense	distal	-6	no	7.073	7.508	EPSD	TCGA;ICGC;COSMIC	5.915	Up-regulation
CMGC_MAPK_p38_MAPK14_ST	Q15075	EEA1	Q16539	MAPK14	T1392	S1395F	1395	Missense	distal	3	no	13.215	13.323	PhosphoSitePlus	TCGA;ICGC;GDSC;CCLE	5.915	Up-regulation
CMGC_MAPK_p38_MAPK14_ST	P13726	F3	Q16539	MAPK14	S120	N114Y	114	Missense	distal	-6	no	6.215	5.872	EPSD	TCGA;ICGC;COSMIC	5.915	Loss
CMGC_MAPK_p38_MAPK14_ST	P13726	F3	Q16539	MAPK14	S120	E127D	127	Missense	distal	7	no	6.215	6.020	EPSD	TCGA;ICGC;COSMIC	5.915	Down-regulation
CMGC_MAPK_p38_MAPK14_ST	O75676	RPS6KA4	Q16539	MAPK14	S196	T200I	200	Missense	distal	4	no	7.170	6.643	PhosphoSitePlus	TCGA;ICGC	5.915	Down-regulation
CMGC_MAPK_p38_MAPK14_ST	O75676	RPS6KA4	Q16539	MAPK14	T542	D541N	541	Missense	proximal	-1	no	8.890	8.705	EPSD	TCGA;ICGC;COSMIC	5.915	Down-regulation
CMGC_MAPK_p38_MAPK14_ST	O75676	RPS6KA4	Q16539	MAPK14	T568	M566L	566	Missense	proximal	-2	no	11.294	10.726	EPSD	TCGA	5.915	Down-regulation
CMGC_MAPK_p38_MAPK14_ST	O75676	RPS6KA4	Q16539	MAPK14	S672	G677D	677	Missense	distal	5	no	6.445	6.156	EPSD	TCGA;COSMIC	5.915	Down-regulation
CMGC_MAPK_p38_MAPK14_ST	O75676	RPS6KA4	Q16539	MAPK14	S682	P684S	684	Missense	proximal	2	no	12.080	12.457	EPSD	TCGA;COSMIC;CCLE	5.915	Up-regulation
CMGC_MAPK_p38_MAPK14_ST	O75676	RPS6KA4	Q16539	MAPK14	S682	G677D	677	Missense	distal	-5	no	12.080	12.322	EPSD	TCGA;COSMIC	5.915	Up-regulation
CMGC_MAPK_p38_MAPK14_ST	O75676	RPS6KA4	Q16539	MAPK14	T687	P684S	684	Missense	distal	-3	no	10.489	11.253	EPSD	TCGA;COSMIC;CCLE	5.915	Up-regulation
CMGC_MAPK_p38_MAPK14_ST	O75676	RPS6KA4	Q16539	MAPK14	T739	S737C	737	Missense	proximal	-2	no	6.015	4.880	EPSD	TCGA;ICGC	5.915	Loss
CMGC_MAPK_p38_MAPK14_ST	O75676	RPS6KA4	Q16539	MAPK14	T739	R742L	742	Missense	distal	3	no	6.015	6.061	EPSD	TCGA;ICGC;COSMIC	5.915	Up-regulation
CMGC_MAPK_p38_MAPK14_ST	O75676	RPS6KA4	Q16539	MAPK14	T739	T739I	739	Missense	central	0	yes	6.015	0.000	EPSD	TCGA;COSMIC	5.915	Loss
CMGC_MAPK_p38_MAPK14_ST	O75676	RPS6KA4	Q16539	MAPK14	T739	S741F	741	Missense	proximal	2	no	6.015	5.349	EPSD	TCGA;COSMIC	5.915	Loss
CMGC_MAPK_p38_MAPK14_ST	O75676	RPS6KA4	Q16539	MAPK14	S745	R742L	742	Missense	distal	-3	no	12.491	10.247	EPSD	TCGA;ICGC;COSMIC	5.915	Down-regulation
CMGC_MAPK_p38_MAPK14_ST	O75676	RPS6KA4	Q16539	MAPK14	S745	T739I	739	Missense	distal	-6	no	12.491	11.469	EPSD	TCGA;COSMIC	5.915	Down-regulation
CMGC_MAPK_p38_MAPK14_ST	O75676	RPS6KA4	Q16539	MAPK14	S745	S741F	741	Missense	distal	-4	no	12.491	13.195	EPSD	TCGA;COSMIC	5.915	Up-regulation
CMGC_MAPK_p38_MAPK14_ST	P22415	USF1	Q16539	MAPK14	T153	P155L	155	Missense	proximal	2	no	9.923	9.810	PhosphoSitePlus	TCGA;COSMIC	5.915	Down-regulation
CMGC_MAPK_p38_MAPK14_ST	P22415	USF1	Q16539	MAPK14	T153	P154L	154	Missense	proximal	1	no	9.923	1.872	PhosphoSitePlus	TCGA;COSMIC	5.915	Loss
CMGC_MAPK_p38_MAPK14_ST	P22415	USF1	Q16539	MAPK14	S186	P192L	192	Missense	distal	6	no	10.311	10.172	EPSD	TCGA;COSMIC	5.915	Down-regulation
CMGC_MAPK_p38_MAPK14_ST	P22415	USF1	Q16539	MAPK14	T195	R196W	196	Missense	proximal	1	no	4.813	6.779	EPSD	TCGA;ICGC;COSMIC	5.915	Gain
CMGC_MAPK_p38_MAPK14_ST	P22415	USF1	Q16539	MAPK14	S233	T234P	234	Missense	proximal	1	no	4.712	12.165	EPSD	TCGA	5.915	Gain
CMGC_MAPK_p38_MAPK14_ST	P10275	AR	Q16539	MAPK14	S96	G95S	95	Missense	proximal	-1	no	7.133	6.920	EPSD	TCGA;ICGC;COSMIC	5.915	Down-regulation
CMGC_MAPK_p38_MAPK14_ST	P10275	AR	Q16539	MAPK14	S96	E93D	93	Missense	distal	-3	no	7.133	6.927	EPSD	TCGA;ICGC;COSMIC	5.915	Down-regulation
CMGC_MAPK_p38_MAPK14_ST	P10275	AR	Q16539	MAPK14	S258	R264W	264	Missense	distal	6	no	8.031	7.767	EPSD	TCGA;ICGC;COSMIC	5.915	Down-regulation
CMGC_MAPK_p38_MAPK14_ST	P10275	AR	Q16539	MAPK14	S258	A253V	253	Missense	distal	-5	no	8.031	8.522	EPSD	TCGA;ICGC;COSMIC	5.915	Up-regulation
CMGC_MAPK_p38_MAPK14_ST	P10275	AR	Q16539	MAPK14	T282	E289K	289	Missense	distal	7	no	10.084	9.377	EPSD	TCGA;ICGC;COSMIC	5.915	Down-regulation
CMGC_MAPK_p38_MAPK14_ST	P10275	AR	Q16539	MAPK14	T282	R280C	280	Missense	proximal	-2	no	10.084	9.148	EPSD	TCGA;ICGC;COSMIC	5.915	Down-regulation
CMGC_MAPK_p38_MAPK14_ST	P10275	AR	Q16539	MAPK14	S310	E308K	308	Missense	proximal	-2	no	10.302	9.272	EPSD	TCGA;COSMIC	5.915	Down-regulation
CMGC_MAPK_p38_MAPK14_ST	P10275	AR	Q16539	MAPK14	S310	Y316H	316	Missense	distal	6	no	10.302	10.176	EPSD	TCGA;ICGC	5.915	Down-regulation
CMGC_MAPK_p38_MAPK14_ST	P10275	AR	Q16539	MAPK14	S330	E323K	323	Missense	distal	-7	no	6.855	6.801	EPSD	TCGA;ICGC;GDSC;CCLE	5.915	Down-regulation
CMGC_MAPK_p38_MAPK14_ST	P10275	AR	Q16539	MAPK14	S330	E323Q	323	Missense	distal	-7	no	6.855	6.442	EPSD	TCGA;ICGC;COSMIC	5.915	Down-regulation
CMGC_MAPK_p38_MAPK14_ST	P10275	AR	Q16539	MAPK14	S330	G326S	326	Missense	distal	-4	no	6.855	6.857	EPSD	TCGA;ICGC	5.915	Up-regulation
CMGC_MAPK_p38_MAPK14_ST	P10275	AR	Q16539	MAPK14	S516	P513S	513	Missense	distal	-3	no	10.977	11.740	EPSD	TCGA;ICGC;COSMIC	5.915	Up-regulation
CMGC_MAPK_p38_MAPK14_ST	P10275	AR	Q16539	MAPK14	T649	E645K	645	Missense	distal	-4	no	7.228	7.453	EPSD	TCGA;ICGC;COSMIC	5.915	Up-regulation
CMGC_MAPK_p38_MAPK14_ST	P10275	AR	Q16539	MAPK14	S651	E645K	645	Missense	distal	-6	no	13.990	13.576	PhosphoSitePlus	TCGA;ICGC;COSMIC	5.915	Down-regulation
CMGC_MAPK_p38_MAPK14_ST	P06400	RB1	Q16539	MAPK14	S149	M148T	148	Missense	proximal	-1	no	6.456	6.449	EPSD	TCGA;ICGC;COSMIC	5.915	Down-regulation
CMGC_MAPK_p38_MAPK14_ST	P06400	RB1	Q16539	MAPK14	S149	T142A	142	Missense	distal	-7	no	6.456	6.639	EPSD	TCGA;ICGC	5.915	Up-regulation
CMGC_MAPK_p38_MAPK14_ST	P06400	RB1	Q16539	MAPK14	S230	F226L	226	Missense	distal	-4	no	10.059	9.954	EPSD	TCGA;ICGC;COSMIC	5.915	Down-regulation
CMGC_MAPK_p38_MAPK14_ST	P06400	RB1	Q16539	MAPK14	S230	Y225C	225	Missense	distal	-5	no	10.059	10.311	EPSD	TCGA;ICGC	5.915	Up-regulation
CMGC_MAPK_p38_MAPK14_ST	P06400	RB1	Q16539	MAPK14	S249	R255Q	255	Missense	distal	6	no	10.723	10.735	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	5.915	Up-regulation
CMGC_MAPK_p38_MAPK14_ST	P06400	RB1	Q16539	MAPK14	S249	R251Q	251	Missense	proximal	2	no	10.723	10.297	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC;CCLE	5.915	Down-regulation
CMGC_MAPK_p38_MAPK14_ST	P06400	RB1	Q16539	MAPK14	S249	P245A	245	Missense	distal	-4	no	10.723	10.675	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	5.915	Down-regulation
CMGC_MAPK_p38_MAPK14_ST	P06400	RB1	Q16539	MAPK14	T252	R255Q	255	Missense	distal	3	no	9.952	9.992	PhosphoSitePlus;EPSD	TCGA;ICGC;COSMIC	5.915	Up-regulation
CMGC_MAPK_p38_MAPK14_ST	P06400	RB1	Q16539	MAPK14	T252	R251Q	251	Missense	proximal	-1	no	9.952	10.040	PhosphoSitePlus;EPSD	TCGA;ICGC;COSMIC;CCLE	5.915	Up-regulation
CMGC_MAPK_p38_MAPK14_ST	P06400	RB1	Q16539	MAPK14	T252	P245A	245	Missense	distal	-7	no	9.952	10.152	PhosphoSitePlus;EPSD	TCGA;ICGC;COSMIC	5.915	Up-regulation
CMGC_MAPK_p38_MAPK14_ST	P06400	RB1	Q16539	MAPK14	T252	R259S	259	Missense	distal	7	no	9.952	9.917	PhosphoSitePlus;EPSD	TCGA;ICGC;COSMIC	5.915	Down-regulation
CMGC_MAPK_p38_MAPK14_ST	P06400	RB1	Q16539	MAPK14	S350	S350I	350	Missense	central	0	yes	7.284	0.000	EPSD	TCGA;ICGC;COSMIC;GDSC	5.915	Loss
CMGC_MAPK_p38_MAPK14_ST	P06400	RB1	Q16539	MAPK14	T353	S350I	350	Missense	distal	-3	no	7.218	5.146	EPSD	TCGA;ICGC;COSMIC;GDSC	5.915	Loss
CMGC_MAPK_p38_MAPK14_ST	P06400	RB1	Q16539	MAPK14	T356	S350I	350	Missense	distal	-6	no	12.525	11.230	EPSD	TCGA;ICGC;COSMIC;GDSC	5.915	Down-regulation
CMGC_MAPK_p38_MAPK14_ST	P06400	RB1	Q16539	MAPK14	T373	P374A	374	Missense	proximal	1	no	8.453	2.134	EPSD	TCGA;ICGC;COSMIC	5.915	Loss
CMGC_MAPK_p38_MAPK14_ST	P06400	RB1	Q16539	MAPK14	T373	M379L	379	Missense	distal	6	no	8.453	8.277	EPSD	TCGA;ICGC;COSMIC	5.915	Down-regulation
CMGC_MAPK_p38_MAPK14_ST	P06400	RB1	Q16539	MAPK14	S567	S567L	567	Missense	central	0	yes	7.930	0.000	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	5.915	Loss
CMGC_MAPK_p38_MAPK14_ST	P06400	RB1	Q16539	MAPK14	S567	W563S	563	Missense	distal	-4	no	7.930	7.290	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	5.915	Down-regulation
CMGC_MAPK_p38_MAPK14_ST	P06400	RB1	Q16539	MAPK14	S567	A562E	562	Missense	distal	-5	no	7.930	7.567	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	5.915	Down-regulation
CMGC_MAPK_p38_MAPK14_ST	P06400	RB1	Q16539	MAPK14	S608	D604G	604	Missense	distal	-4	no	11.823	11.327	EPSD	TCGA;ICGC;COSMIC	5.915	Down-regulation
CMGC_MAPK_p38_MAPK14_ST	P06400	RB1	Q16539	MAPK14	S780	I782M	782	Missense	proximal	2	no	7.541	7.766	EPSD	TCGA;ICGC;COSMIC	5.915	Up-regulation
CMGC_MAPK_p38_MAPK14_ST	P06400	RB1	Q16539	MAPK14	S780	R787Q	787	Missense	distal	7	no	7.541	7.347	EPSD	TCGA;ICGC;COSMIC	5.915	Down-regulation
CMGC_MAPK_p38_MAPK14_ST	P06400	RB1	Q16539	MAPK14	S788	I782M	782	Missense	distal	-6	no	8.319	8.754	EPSD	TCGA;ICGC;COSMIC	5.915	Up-regulation
CMGC_MAPK_p38_MAPK14_ST	P06400	RB1	Q16539	MAPK14	S788	S788N	788	Missense	central	0	yes	8.319	0.000	EPSD	TCGA;ICGC;COSMIC	5.915	Loss
CMGC_MAPK_p38_MAPK14_ST	P06400	RB1	Q16539	MAPK14	S788	R787Q	787	Missense	proximal	-1	no	8.319	8.408	EPSD	TCGA;ICGC;COSMIC	5.915	Up-regulation
CMGC_MAPK_p38_MAPK14_ST	P06400	RB1	Q16539	MAPK14	S795	S788N	788	Missense	distal	-7	no	7.500	7.289	EPSD	TCGA;ICGC;COSMIC	5.915	Down-regulation
CMGC_MAPK_p38_MAPK14_ST	P06400	RB1	Q16539	MAPK14	S795	R798W	798	Missense	distal	3	no	7.500	7.584	EPSD	TCGA;ICGC;COSMIC;GDSC	5.915	Up-regulation
CMGC_MAPK_p38_MAPK14_ST	P06400	RB1	Q16539	MAPK14	S807	N803S	803	Missense	distal	-4	no	12.132	12.059	EPSD	TCGA;ICGC	5.915	Down-regulation
CMGC_MAPK_p38_MAPK14_ST	P06400	RB1	Q16539	MAPK14	T821	P827S	827	Missense	distal	6	no	8.094	8.082	EPSD	TCGA;ICGC;COSMIC	5.915	Down-regulation
CMGC_MAPK_p38_MAPK14_ST	P06400	RB1	Q16539	MAPK14	T826	P827S	827	Missense	proximal	1	no	10.042	2.758	EPSD	TCGA;ICGC;COSMIC	5.915	Loss
CMGC_MAPK_p38_MAPK14_ST	P17181	IFNAR1	Q16539	MAPK14	S532	S529F	529	Missense	distal	-3	no	7.024	4.317	PhosphoSitePlus	TCGA;COSMIC	5.915	Loss
CMGC_MAPK_p38_MAPK14_ST	P17181	IFNAR1	Q16539	MAPK14	S546	K547T	547	Missense	proximal	1	no	5.187	6.741	EPSD	TCGA	5.915	Gain
CMGC_MAPK_p38_MAPK14_ST	P40763	STAT3	Q16539	MAPK14	S25	S25N	25	Missense	central	0	yes	7.291	0.000	EPSD	TCGA;COSMIC	5.915	Loss
CMGC_MAPK_p38_MAPK14_ST	P40763	STAT3	Q16539	MAPK14	S25	R31Q	31	Missense	distal	6	no	7.291	7.303	EPSD	TCGA;ICGC;COSMIC	5.915	Up-regulation
CMGC_MAPK_p38_MAPK14_ST	P40763	STAT3	Q16539	MAPK14	S25	M28K	28	Missense	distal	3	no	7.291	7.298	EPSD	TCGA;ICGC;COSMIC	5.915	Up-regulation
CMGC_MAPK_p38_MAPK14_ST	P40763	STAT3	Q16539	MAPK14	S25	L21V	21	Missense	distal	-4	no	7.291	7.014	EPSD	TCGA	5.915	Down-regulation
CMGC_MAPK_p38_MAPK14_ST	P40763	STAT3	Q16539	MAPK14	T440	E444K	444	Missense	distal	4	no	6.042	5.576	EPSD	TCGA;ICGC;COSMIC	5.915	Loss
CMGC_MAPK_p38_MAPK14_ST	P40763	STAT3	Q16539	MAPK14	T440	E435K	435	Missense	distal	-5	no	6.042	6.376	EPSD	TCGA;ICGC;COSMIC	5.915	Up-regulation
CMGC_MAPK_p38_MAPK14_ST	P40763	STAT3	Q16539	MAPK14	T440	T440I	440	Missense	central	0	yes	6.042	0.000	EPSD	TCGA	5.915	Loss
CMGC_MAPK_p38_MAPK14_ST	P40763	STAT3	Q16539	MAPK14	S691	Y686D	686	Missense	distal	-5	no	7.052	7.227	EPSD	TCGA;ICGC	5.915	Up-regulation
CMGC_MAPK_p38_MAPK14_ST	P40763	STAT3	Q16539	MAPK14	T714	S719N	719	Missense	distal	5	no	8.540	8.204	EPSD	TCGA;ICGC	5.915	Down-regulation
CMGC_MAPK_p38_MAPK14_ST	P40763	STAT3	Q16539	MAPK14	S727	R729H	729	Missense	proximal	2	no	13.540	13.157	PhosphoSitePlus	TCGA;ICGC;COSMIC;GDSC;CCLE	5.915	Down-regulation
CMGC_MAPK_p38_MAPK14_ST	P40763	STAT3	Q16539	MAPK14	S727	P725L	725	Missense	proximal	-2	no	13.540	12.160	PhosphoSitePlus	TCGA;ICGC;COSMIC	5.915	Down-regulation
CMGC_MAPK_p38_MAPK14_ST	O43684	BUB3	Q16539	MAPK14	S23	P24S	24	Missense	proximal	1	no	7.894	0.610	EPSD	TCGA;ICGC;COSMIC	5.915	Loss
CMGC_MAPK_p38_MAPK14_ST	O43684	BUB3	Q16539	MAPK14	T127	V120L	120	Missense	distal	-7	no	12.145	12.570	EPSD	TCGA;ICGC;COSMIC	5.915	Up-regulation
CMGC_MAPK_p38_MAPK14_ST	O43684	BUB3	Q16539	MAPK14	T127	L122P	122	Missense	distal	-5	no	12.145	11.864	EPSD	TCGA;ICGC;COSMIC	5.915	Down-regulation
CMGC_MAPK_p38_MAPK14_ST	O43684	BUB3	Q16539	MAPK14	S211	E213K	213	Missense	proximal	2	no	8.745	8.431	PhosphoSitePlus	TCGA;ICGC;COSMIC	5.915	Down-regulation
CMGC_MAPK_p38_MAPK14_ST	O43684	BUB3	Q16539	MAPK14	S211	S211R	211	Missense	central	0	yes	8.745	0.000	PhosphoSitePlus	TCGA;ICGC;COSMIC	5.915	Loss
CMGC_MAPK_p38_MAPK14_ST	O43684	BUB3	Q16539	MAPK14	S325	E320K	320	Missense	distal	-5	no	7.732	8.066	EPSD	TCGA;ICGC;COSMIC	5.915	Up-regulation
CMGC_MAPK_p38_MAPK14_ST	P10415	BCL2	Q16539	MAPK14	T56	A61T	61	Missense	distal	5	no	9.545	10.017	PhosphoSitePlus;EPSD	TCGA;ICGC;COSMIC;CCLE	5.915	Up-regulation
CMGC_MAPK_p38_MAPK14_ST	P30279	CCND2	Q16539	MAPK14	T280	R285W	285	Missense	distal	5	no	9.625	8.731	PhosphoSitePlus	TCGA;ICGC;COSMIC	5.915	Down-regulation
CMGC_MAPK_p38_MAPK14_ST	P30279	CCND2	Q16539	MAPK14	T280	D273N	273	Missense	distal	-7	no	9.625	9.845	PhosphoSitePlus	TCGA;ICGC;COSMIC	5.915	Up-regulation
CMGC_MAPK_p38_MAPK14_ST	P30279	CCND2	Q16539	MAPK14	T280	R285Q	285	Missense	distal	5	no	9.625	9.276	PhosphoSitePlus	TCGA;ICGC	5.915	Down-regulation
CMGC_MAPK_p38_MAPK14_ST	P13473	LAMP2	Q16539	MAPK14	T211	P218T	218	Missense	distal	7	no	11.924	11.825	PhosphoSitePlus;EPSD	TCGA;COSMIC	5.915	Down-regulation
CMGC_MAPK_p38_MAPK14_ST	P13473	LAMP2	Q16539	MAPK14	T213	P218T	218	Missense	distal	5	no	12.977	13.261	EPSD;PhosphoSitePlus	TCGA;COSMIC	5.915	Up-regulation
CMGC_MAPK_p38_MAPK14_ST	P13473	LAMP2	Q16539	MAPK14	S276	T269A	269	Missense	distal	-7	no	7.089	7.272	EPSD	TCGA;COSMIC	5.915	Up-regulation
CMGC_MAPK_p38_MAPK14_ST	P55273	CDKN2D	Q16539	MAPK14	S66	S73C	73	Missense	distal	7	no	11.408	10.842	PhosphoSitePlus	TCGA;ICGC;COSMIC	5.915	Down-regulation
CMGC_MAPK_p38_MAPK14_ST	P55273	CDKN2D	Q16539	MAPK14	S76	S73C	73	Missense	distal	-3	no	7.827	6.144	EPSD	TCGA;ICGC;COSMIC	5.915	Down-regulation
CMGC_MAPK_p38_MAPK14_ST	P55273	CDKN2D	Q16539	MAPK14	T141	R135S	135	Missense	distal	-6	no	10.969	11.075	EPSD	TCGA;ICGC;COSMIC	5.915	Up-regulation
CMGC_MAPK_p38_MAPK14_ST	P55273	CDKN2D	Q16539	MAPK14	T141	R134H	134	Missense	distal	-7	no	10.969	10.674	EPSD	TCGA;ICGC;COSMIC	5.915	Down-regulation
CMGC_MAPK_p38_MAPK14_ST	P48436	SOX9	Q16539	MAPK14	S23	G17S	17	Missense	distal	-6	no	12.129	12.610	EPSD	TCGA;ICGC;COSMIC	5.915	Up-regulation
CMGC_MAPK_p38_MAPK14_ST	P48436	SOX9	Q16539	MAPK14	S33	G40R	40	Missense	distal	7	no	11.945	12.122	EPSD	TCGA;ICGC;COSMIC	5.915	Up-regulation
CMGC_MAPK_p38_MAPK14_ST	P48436	SOX9	Q16539	MAPK14	S33	A31V	31	Missense	proximal	-2	no	11.945	11.530	EPSD	TCGA;ICGC;COSMIC	5.915	Down-regulation
CMGC_MAPK_p38_MAPK14_ST	P48436	SOX9	Q16539	MAPK14	S33	P36S	36	Missense	distal	3	no	11.945	11.904	EPSD	TCGA;ICGC;COSMIC	5.915	Down-regulation
CMGC_MAPK_p38_MAPK14_ST	P48436	SOX9	Q16539	MAPK14	T46	G40R	40	Missense	distal	-6	no	5.620	5.995	EPSD	TCGA;ICGC;COSMIC	5.915	Gain
CMGC_MAPK_p38_MAPK14_ST	P48436	SOX9	Q16539	MAPK14	T46	F53L	53	Missense	distal	7	no	5.620	6.106	EPSD	TCGA;ICGC;COSMIC	5.915	Gain
CMGC_MAPK_p38_MAPK14_ST	P48436	SOX9	Q16539	MAPK14	S199	P200S	200	Missense	proximal	1	no	8.993	1.709	EPSD	TCGA;ICGC;COSMIC	5.915	Loss
CMGC_MAPK_p38_MAPK14_ST	P48436	SOX9	Q16539	MAPK14	S199	A206V	206	Missense	distal	7	no	8.993	8.884	EPSD	TCGA;ICGC	5.915	Down-regulation
CMGC_MAPK_p38_MAPK14_ST	P48436	SOX9	Q16539	MAPK14	S211	M218I	218	Missense	distal	7	no	11.044	10.441	PhosphoSitePlus	TCGA;ICGC;COSMIC	5.915	Down-regulation
CMGC_MAPK_p38_MAPK14_ST	P48436	SOX9	Q16539	MAPK14	S211	S214P	214	Missense	distal	3	no	11.044	11.084	PhosphoSitePlus	TCGA;ICGC;COSMIC	5.915	Up-regulation
CMGC_MAPK_p38_MAPK14_ST	P48436	SOX9	Q16539	MAPK14	S211	A206V	206	Missense	distal	-5	no	11.044	11.536	PhosphoSitePlus	TCGA;ICGC	5.915	Up-regulation
CMGC_MAPK_p38_MAPK14_ST	P48436	SOX9	Q16539	MAPK14	S214	M218I	218	Missense	distal	4	no	7.938	7.473	EPSD	TCGA;ICGC;COSMIC	5.915	Down-regulation
CMGC_MAPK_p38_MAPK14_ST	P48436	SOX9	Q16539	MAPK14	S214	S214P	214	Missense	central	0	yes	7.938	0.000	EPSD	TCGA;ICGC;COSMIC	5.915	Loss
CMGC_MAPK_p38_MAPK14_ST	P48436	SOX9	Q16539	MAPK14	S223	M218I	218	Missense	distal	-5	no	10.432	10.679	EPSD	TCGA;ICGC;COSMIC	5.915	Up-regulation
CMGC_MAPK_p38_MAPK14_ST	P48436	SOX9	Q16539	MAPK14	T236	P235A	235	Missense	proximal	-1	no	11.834	11.802	EPSD	TCGA;ICGC;COSMIC	5.915	Down-regulation
CMGC_MAPK_p38_MAPK14_ST	P48436	SOX9	Q16539	MAPK14	T240	P235A	235	Missense	distal	-5	no	9.073	8.736	EPSD	TCGA;ICGC;COSMIC	5.915	Down-regulation
CMGC_MAPK_p38_MAPK14_ST	P48436	SOX9	Q16539	MAPK14	S494	H497N	497	Missense	distal	3	no	8.400	8.346	EPSD	TCGA;ICGC;COSMIC	5.915	Down-regulation
CMGC_MAPK_p38_MAPK14_ST	P48436	SOX9	Q16539	MAPK14	S494	S494N	494	Missense	central	0	yes	8.400	0.000	EPSD	TCGA;ICGC;COSMIC	5.915	Loss
CMGC_MAPK_p38_MAPK14_ST	P48436	SOX9	Q16539	MAPK14	S494	P490L	490	Missense	distal	-4	no	8.400	8.912	EPSD	TCGA;ICGC	5.915	Up-regulation
CMGC_MAPK_p38_MAPK14_ST	Q8TE85	GRHL3	Q16539	MAPK14	S105	T98M	98	Missense	distal	-7	no	10.630	10.684	EPSD	TCGA;ICGC;COSMIC	5.915	Up-regulation
CMGC_MAPK_p38_MAPK14_ST	Q8TE85	GRHL3	Q16539	MAPK14	S105	L103I	103	Missense	proximal	-2	no	10.630	11.191	EPSD	TCGA;ICGC;COSMIC	5.915	Up-regulation
CMGC_MAPK_p38_MAPK14_ST	Q8TE85	GRHL3	Q16539	MAPK14	S105	P102T	102	Missense	distal	-3	no	10.630	11.076	EPSD	TCGA;ICGC;COSMIC	5.915	Up-regulation
CMGC_MAPK_p38_MAPK14_ST	Q8TE85	GRHL3	Q16539	MAPK14	S215	P216L	216	Missense	proximal	1	no	9.238	1.187	EPSD	TCGA;ICGC;COSMIC;CCLE	5.915	Loss
CMGC_MAPK_p38_MAPK14_ST	Q8TE85	GRHL3	Q16539	MAPK14	S215	E217G	217	Missense	proximal	2	no	9.238	9.044	EPSD	TCGA;ICGC;COSMIC	5.915	Down-regulation
CMGC_MAPK_p38_MAPK14_ST	Q8TE85	GRHL3	Q16539	MAPK14	S215	S215F	215	Missense	central	0	yes	9.238	0.000	EPSD	TCGA;ICGC;COSMIC	5.915	Loss
CMGC_MAPK_p38_MAPK14_ST	Q8TE85	GRHL3	Q16539	MAPK14	T454	P456H	456	Missense	proximal	2	no	7.761	7.610	PhosphoSitePlus	TCGA;ICGC;COSMIC	5.915	Down-regulation
CMGC_MAPK_p38_MAPK14_ST	Q8TE85	GRHL3	Q16539	MAPK14	S493	E500Q	500	Missense	distal	7	no	14.036	13.659	EPSD	TCGA;ICGC;COSMIC	5.915	Down-regulation
CMGC_MAPK_p38_MAPK14_ST	Q8TE85	GRHL3	Q16539	MAPK14	S493	R490C	490	Missense	distal	-3	no	14.036	11.840	EPSD	TCGA;ICGC;COSMIC;CCLE	5.915	Down-regulation
CMGC_MAPK_p38_MAPK14_ST	Q06330	RBPJ	Q16539	MAPK14	S7	E11K	11	Missense	distal	4	no	13.829	13.363	EPSD	TCGA;ICGC;COSMIC	5.915	Down-regulation
CMGC_MAPK_p38_MAPK14_ST	Q06330	RBPJ	Q16539	MAPK14	S18	E11K	11	Missense	distal	-7	no	9.580	9.526	EPSD	TCGA;ICGC;COSMIC	5.915	Down-regulation
CMGC_MAPK_p38_MAPK14_ST	Q06330	RBPJ	Q16539	MAPK14	S18	R25W	25	Missense	distal	7	no	9.580	8.892	EPSD	TCGA;COSMIC	5.915	Down-regulation
CMGC_MAPK_p38_MAPK14_ST	Q06330	RBPJ	Q16539	MAPK14	S195	N191T	191	Missense	distal	-4	no	7.443	7.647	EPSD	TCGA;COSMIC	5.915	Up-regulation
CMGC_MAPK_p38_MAPK14_ST	Q06330	RBPJ	Q16539	MAPK14	T445	E447Q	447	Missense	proximal	2	no	10.153	9.617	EPSD	TCGA;COSMIC	5.915	Down-regulation
CMGC_MAPK_p38_MAPK14_ST	Q06330	RBPJ	Q16539	MAPK14	T445	R451W	451	Missense	distal	6	no	10.153	9.890	EPSD	TCGA;COSMIC	5.915	Down-regulation
CMGC_MAPK_p38_MAPK14_ST	Q06330	RBPJ	Q16539	MAPK14	T445	P450L	450	Missense	distal	5	no	10.153	9.656	EPSD	TCGA;COSMIC	5.915	Down-regulation
CMGC_MAPK_p38_MAPK14_ST	Q9C026	TRIM9	Q16539	MAPK14	T41	R35H	35	Missense	distal	-6	no	12.387	11.424	EPSD	TCGA;ICGC;COSMIC	5.915	Down-regulation
CMGC_MAPK_p38_MAPK14_ST	Q9C026	TRIM9	Q16539	MAPK14	T41	N36H	36	Missense	distal	-5	no	12.387	12.685	EPSD	TCGA	5.915	Up-regulation
CMGC_MAPK_p38_MAPK14_ST	Q9C026	TRIM9	Q16539	MAPK14	S46	S49R	49	Missense	distal	3	no	10.278	10.306	EPSD	TCGA	5.915	Up-regulation
CMGC_MAPK_p38_MAPK14_ST	Q9C026	TRIM9	Q16539	MAPK14	S46	A53T	53	Missense	distal	7	no	10.278	9.935	EPSD	TCGA;ICGC;COSMIC	5.915	Down-regulation
CMGC_MAPK_p38_MAPK14_ST	Q9C026	TRIM9	Q16539	MAPK14	T406	Q399R	399	Missense	distal	-7	no	10.274	10.368	EPSD	TCGA;ICGC;COSMIC	5.915	Up-regulation
CMGC_MAPK_p38_MAPK14_ST	Q9C026	TRIM9	Q16539	MAPK14	T406	W400C	400	Missense	distal	-6	no	10.274	10.406	EPSD	TCGA;ICGC;COSMIC	5.915	Up-regulation
CMGC_MAPK_p38_MAPK14_ST	Q9C026	TRIM9	Q16539	MAPK14	T406	T410A	410	Missense	distal	4	no	10.274	10.230	EPSD	TCGA;ICGC;COSMIC	5.915	Down-regulation
CMGC_MAPK_p38_MAPK14_ST	Q9C026	TRIM9	Q16539	MAPK14	S625	S632L	632	Missense	distal	7	no	6.011	5.626	EPSD	TCGA;ICGC;COSMIC	5.915	Loss
CMGC_MAPK_p38_MAPK14_ST	Q9C026	TRIM9	Q16539	MAPK14	S625	R624Q	624	Missense	proximal	-1	no	6.011	6.099	EPSD	TCGA;ICGC;COSMIC	5.915	Up-regulation
CMGC_MAPK_p38_MAPK14_ST	Q9C026	TRIM9	Q16539	MAPK14	S625	V620G	620	Missense	distal	-5	no	6.011	5.788	EPSD	TCGA;ICGC;COSMIC	5.915	Loss
CMGC_MAPK_p38_MAPK14_ST	Q07817	BCL2L1	Q16539	MAPK14	S62	A64V	64	Missense	proximal	2	no	13.524	13.360	PhosphoSitePlus	TCGA	5.915	Down-regulation
CMGC_MAPK_p38_MAPK14_ST	Q07817	BCL2L1	Q16539	MAPK14	T115	T109A	109	Missense	distal	-6	no	10.425	10.156	EPSD	TCGA;ICGC;COSMIC	5.915	Down-regulation
CMGC_MAPK_p38_MAPK14_ST	Q07817	BCL2L1	Q16539	MAPK14	T115	Q121P	121	Missense	distal	6	no	10.425	10.426	EPSD	TCGA;ICGC;COSMIC	5.915	Up-regulation
CMGC_MAPK_p38_MAPK14_ST	Q07817	BCL2L1	Q16539	MAPK14	T115	Q121H	121	Missense	distal	6	no	10.425	10.306	EPSD	TCGA;ICGC;COSMIC	5.915	Down-regulation
CMGC_MAPK_p38_MAPK14_ST	Q02156	PRKCE	Q16539	MAPK14	T228	V232L	232	Missense	distal	4	no	9.657	9.318	EPSD	TCGA;ICGC;COSMIC	5.915	Down-regulation
CMGC_MAPK_p38_MAPK14_ST	Q02156	PRKCE	Q16539	MAPK14	T309	D305Y	305	Missense	distal	-4	no	8.689	8.192	EPSD	TCGA;ICGC;COSMIC	5.915	Down-regulation
CMGC_MAPK_p38_MAPK14_ST	Q02156	PRKCE	Q16539	MAPK14	T309	D305N	305	Missense	distal	-4	no	8.689	8.269	EPSD	TCGA;ICGC;COSMIC	5.915	Down-regulation
CMGC_MAPK_p38_MAPK14_ST	Q02156	PRKCE	Q16539	MAPK14	T309	P310L	310	Missense	proximal	1	no	8.689	0.638	EPSD	TCGA;ICGC;COSMIC	5.915	Loss
CMGC_MAPK_p38_MAPK14_ST	Q02156	PRKCE	Q16539	MAPK14	T309	V308I	308	Missense	proximal	-1	no	8.689	8.451	EPSD	TCGA;ICGC;COSMIC	5.915	Down-regulation
CMGC_MAPK_p38_MAPK14_ST	Q02156	PRKCE	Q16539	MAPK14	T309	L306M	306	Missense	distal	-3	no	8.689	8.997	EPSD	TCGA;ICGC;COSMIC	5.915	Up-regulation
CMGC_MAPK_p38_MAPK14_ST	Q02156	PRKCE	Q16539	MAPK14	S336	E341K	341	Missense	distal	5	no	6.358	5.791	EPSD	TCGA;ICGC;COSMIC	5.915	Loss
CMGC_MAPK_p38_MAPK14_ST	Q02156	PRKCE	Q16539	MAPK14	S337	E341K	341	Missense	distal	4	no	12.983	12.517	EPSD	TCGA;ICGC;COSMIC	5.915	Down-regulation
CMGC_MAPK_p38_MAPK14_ST	Q02156	PRKCE	Q16539	MAPK14	S346	E341K	341	Missense	distal	-5	no	7.060	7.394	EPSD	TCGA;ICGC;COSMIC	5.915	Up-regulation
CMGC_MAPK_p38_MAPK14_ST	Q02156	PRKCE	Q16539	MAPK14	S380	S381F	381	Missense	proximal	1	no	6.788	8.068	EPSD	TCGA;ICGC	5.915	Up-regulation
CMGC_MAPK_p38_MAPK14_ST	Q02156	PRKCE	Q16539	MAPK14	S380	R377L	377	Missense	distal	-3	no	6.788	4.544	EPSD	TCGA;ICGC;COSMIC	5.915	Loss
CMGC_MAPK_p38_MAPK14_ST	Q02156	PRKCE	Q16539	MAPK14	S380	E374K	374	Missense	distal	-6	no	6.788	6.374	EPSD	TCGA;ICGC;COSMIC	5.915	Down-regulation
CMGC_MAPK_p38_MAPK14_ST	Q02156	PRKCE	Q16539	MAPK14	S381	S381F	381	Missense	central	0	yes	12.483	0.000	EPSD	TCGA;ICGC	5.915	Loss
CMGC_MAPK_p38_MAPK14_ST	Q02156	PRKCE	Q16539	MAPK14	S381	S388R	388	Missense	distal	7	no	12.483	12.518	EPSD	TCGA;ICGC;COSMIC	5.915	Up-regulation
CMGC_MAPK_p38_MAPK14_ST	Q02156	PRKCE	Q16539	MAPK14	S381	R377L	377	Missense	distal	-4	no	12.483	13.072	EPSD	TCGA;ICGC;COSMIC	5.915	Up-regulation
CMGC_MAPK_p38_MAPK14_ST	Q02156	PRKCE	Q16539	MAPK14	S381	E374K	374	Missense	distal	-7	no	12.483	12.430	EPSD	TCGA;ICGC;COSMIC	5.915	Down-regulation
CMGC_MAPK_p38_MAPK14_ST	Q02156	PRKCE	Q16539	MAPK14	S388	S381F	381	Missense	distal	-7	no	11.577	10.831	EPSD	TCGA;ICGC	5.915	Down-regulation
CMGC_MAPK_p38_MAPK14_ST	Q02156	PRKCE	Q16539	MAPK14	S388	S388R	388	Missense	central	0	yes	11.577	0.000	EPSD	TCGA;ICGC;COSMIC	5.915	Loss
CMGC_MAPK_p38_MAPK14_ST	Q02156	PRKCE	Q16539	MAPK14	T566	Y573C	573	Missense	distal	7	no	6.524	5.916	EPSD	TCGA	5.915	Down-regulation
CMGC_MAPK_p38_MAPK14_ST	P23769	GATA2	Q16539	MAPK14	S119	S119R	119	Missense	central	0	yes	9.445	0.000	EPSD	TCGA;ICGC	5.915	Loss
CMGC_MAPK_p38_MAPK14_ST	P23769	GATA2	Q16539	MAPK14	S119	T124M	124	Missense	distal	5	no	9.445	9.133	EPSD	TCGA;ICGC;COSMIC	5.915	Down-regulation
CMGC_MAPK_p38_MAPK14_ST	P23769	GATA2	Q16539	MAPK14	T176	P177S	177	Missense	proximal	1	no	6.856	-0.427	EPSD	TCGA;ICGC;COSMIC	5.915	Loss
CMGC_MAPK_p38_MAPK14_ST	P23769	GATA2	Q16539	MAPK14	T176	P175L	175	Missense	proximal	-1	no	6.856	7.042	EPSD	TCGA;ICGC;COSMIC	5.915	Up-regulation
CMGC_MAPK_p38_MAPK14_ST	P23769	GATA2	Q16539	MAPK14	S182	P177S	177	Missense	distal	-5	no	10.864	10.416	EPSD	TCGA;ICGC;COSMIC	5.915	Down-regulation
CMGC_MAPK_p38_MAPK14_ST	P23769	GATA2	Q16539	MAPK14	S182	P175L	175	Missense	distal	-7	no	10.864	10.671	EPSD	TCGA;ICGC;COSMIC	5.915	Down-regulation
CMGC_MAPK_p38_MAPK14_ST	P23769	GATA2	Q16539	MAPK14	T188	S192F	192	Missense	distal	4	no	6.852	5.278	EPSD	TCGA;ICGC;COSMIC	5.915	Loss
CMGC_MAPK_p38_MAPK14_ST	P23769	GATA2	Q16539	MAPK14	S192	S192F	192	Missense	central	0	yes	14.920	0.000	PhosphoSitePlus	TCGA;ICGC;COSMIC	5.915	Loss
CMGC_MAPK_p38_MAPK14_ST	P23769	GATA2	Q16539	MAPK14	T303	R308Q	308	Missense	distal	5	no	9.980	9.630	EPSD	TCGA;ICGC;COSMIC	5.915	Down-regulation
CMGC_MAPK_p38_MAPK14_ST	P23769	GATA2	Q16539	MAPK14	T303	A302T	302	Missense	proximal	-1	no	9.980	10.036	EPSD	TCGA;ICGC;COSMIC	5.915	Up-regulation
CMGC_MAPK_p38_MAPK14_ST	P23769	GATA2	Q16539	MAPK14	T303	A300S	300	Missense	distal	-3	no	9.980	10.392	EPSD	TCGA;ICGC;COSMIC	5.915	Up-regulation
CMGC_MAPK_p38_MAPK14_ST	P02511	CRYAB	Q16539	MAPK14	S19	S19Y	19	Missense	central	0	yes	10.811	0.000	EPSD	TCGA;ICGC;COSMIC	5.915	Loss
CMGC_MAPK_p38_MAPK14_ST	P02511	CRYAB	Q16539	MAPK14	S45	R50W	50	Missense	distal	5	no	10.021	9.127	EPSD	TCGA;ICGC;COSMIC	5.915	Down-regulation
CMGC_MAPK_p38_MAPK14_ST	P02511	CRYAB	Q16539	MAPK14	S59	R56W	56	Missense	distal	-3	no	9.297	6.940	PhosphoSitePlus	TCGA;ICGC	5.915	Down-regulation
CMGC_MAPK_p38_MAPK14_ST	P02511	CRYAB	Q16539	MAPK14	S59	D62G	62	Missense	distal	3	no	9.297	9.287	PhosphoSitePlus	TCGA;ICGC	5.915	Down-regulation
CMGC_MAPK_p38_MAPK14_ST	P02511	CRYAB	Q16539	MAPK14	S85	E87D	87	Missense	proximal	2	no	9.324	8.873	EPSD	TCGA;ICGC	5.915	Down-regulation
CMGC_MAPK_p38_MAPK14_ST	P02511	CRYAB	Q16539	MAPK14	T132	S138L	138	Missense	distal	6	no	6.224	6.097	EPSD	TCGA;ICGC;COSMIC	5.915	Down-regulation
CMGC_MAPK_p38_MAPK14_ST	P02511	CRYAB	Q16539	MAPK14	T162	R157H	157	Missense	distal	-5	no	5.387	5.930	EPSD	TCGA;ICGC	5.915	Gain
CMGC_MAPK_p38_MAPK14_ST	Q15910	EZH2	Q16539	MAPK14	S75	R78H	78	Missense	distal	3	no	7.697	7.768	EPSD	TCGA;ICGC;COSMIC;GDSC;CCLE	5.915	Up-regulation
CMGC_MAPK_p38_MAPK14_ST	Q15910	EZH2	Q16539	MAPK14	S405	K400T	400	Missense	distal	-5	no	6.166	6.524	EPSD	TCGA;COSMIC	5.915	Up-regulation
CMGC_MAPK_p38_MAPK14_ST	Q01844	EWSR1	Q16539	MAPK14	T79	T79I	79	Missense	central	0	yes	12.266	0.000	PhosphoSitePlus	TCGA;ICGC;COSMIC	5.915	Loss
CMGC_MAPK_p38_MAPK14_ST	Q01844	EWSR1	Q16539	MAPK14	T81	T79I	79	Missense	proximal	-2	no	7.685	7.586	EPSD	TCGA;ICGC;COSMIC	5.915	Down-regulation
CMGC_MAPK_p38_MAPK14_ST	P56817	BACE1	Q16539	MAPK14	S59	E62G	62	Missense	distal	3	no	6.121	6.166	EPSD	TCGA;ICGC;COSMIC	5.915	Up-regulation
CMGC_MAPK_p38_MAPK14_ST	P56817	BACE1	Q16539	MAPK14	S83	S83N	83	Missense	central	0	yes	9.038	0.000	PhosphoSitePlus	TCGA;ICGC;COSMIC	5.915	Loss
CMGC_MAPK_p38_MAPK14_ST	P56817	BACE1	Q16539	MAPK14	S83	T87A	87	Missense	distal	4	no	9.038	8.993	PhosphoSitePlus	TCGA;ICGC;COSMIC	5.915	Down-regulation
CMGC_MAPK_p38_MAPK14_ST	P56817	BACE1	Q16539	MAPK14	S83	V77M	77	Missense	distal	-6	no	9.038	9.208	PhosphoSitePlus	TCGA;ICGC;COSMIC	5.915	Up-regulation
CMGC_MAPK_p38_MAPK14_ST	P56817	BACE1	Q16539	MAPK14	S83	M79V	79	Missense	distal	-4	no	9.038	9.290	PhosphoSitePlus	TCGA;ICGC;COSMIC	5.915	Up-regulation
CMGC_MAPK_p38_MAPK14_ST	P56817	BACE1	Q16539	MAPK14	S83	T87M	87	Missense	distal	4	no	9.038	8.976	PhosphoSitePlus	TCGA;ICGC;COSMIC	5.915	Down-regulation
CMGC_MAPK_p38_MAPK14_ST	P56817	BACE1	Q16539	MAPK14	T252	W250R	250	Missense	proximal	-2	no	10.102	10.628	EPSD	TCGA;COSMIC	5.915	Up-regulation
CMGC_MAPK_p38_MAPK14_ST	P56817	BACE1	Q16539	MAPK14	T252	L249I	249	Missense	distal	-3	no	10.102	9.762	EPSD	TCGA	5.915	Down-regulation
CMGC_MAPK_p38_MAPK14_ST	P56817	BACE1	Q16539	MAPK14	T252	R255Q	255	Missense	distal	3	no	10.102	10.143	EPSD	TCGA;COSMIC	5.915	Up-regulation
CMGC_MAPK_p38_MAPK14_ST	O15198	SMAD9	Q16539	MAPK14	S8	S3F	3	Missense	distal	-5	no	5.523	6.308	EPSD	TCGA;ICGC;COSMIC	5.915	Gain
CMGC_MAPK_p38_MAPK14_ST	O15198	SMAD9	Q16539	MAPK14	S12	A17T	17	Missense	distal	5	no	5.677	6.149	EPSD	TCGA;ICGC;COSMIC	5.915	Gain
CMGC_MAPK_p38_MAPK14_ST	O15198	SMAD9	Q16539	MAPK14	S15	A17T	17	Missense	proximal	2	no	12.194	12.222	EPSD	TCGA;ICGC;COSMIC	5.915	Up-regulation
CMGC_MAPK_p38_MAPK14_ST	O15198	SMAD9	Q16539	MAPK14	S15	R20G	20	Missense	distal	5	no	12.194	12.249	EPSD	TCGA;ICGC;COSMIC	5.915	Up-regulation
CMGC_MAPK_p38_MAPK14_ST	O15198	SMAD9	Q16539	MAPK14	S15	S12F	12	Missense	distal	-3	no	12.194	9.487	EPSD	TCGA;ICGC;COSMIC	5.915	Down-regulation
CMGC_MAPK_p38_MAPK14_ST	O15198	SMAD9	Q16539	MAPK14	T136	R132C	132	Missense	distal	-4	no	10.665	11.115	PhosphoSitePlus	TCGA;ICGC	5.915	Up-regulation
CMGC_MAPK_p38_MAPK14_ST	O15198	SMAD9	Q16539	MAPK14	S458	L453V	453	Missense	distal	-5	no	8.843	8.718	EPSD	TCGA;COSMIC	5.915	Down-regulation
CMGC_MAPK_p38_MAPK14_ST	Q92945	KHSRP	Q16539	MAPK14	T100	F105L	105	Missense	distal	5	no	8.246	8.740	EPSD	TCGA;ICGC;COSMIC	5.915	Up-regulation
CMGC_MAPK_p38_MAPK14_ST	Q92945	KHSRP	Q16539	MAPK14	T143	Y149C	149	Missense	distal	6	no	6.478	6.185	EPSD	TCGA;ICGC	5.915	Down-regulation
CMGC_MAPK_p38_MAPK14_ST	Q92945	KHSRP	Q16539	MAPK14	S181	C176F	176	Missense	distal	-5	no	9.083	9.167	EPSD	TCGA;ICGC;COSMIC	5.915	Up-regulation
CMGC_MAPK_p38_MAPK14_ST	Q92945	KHSRP	Q16539	MAPK14	S480	A487T	487	Missense	distal	7	no	9.381	9.037	EPSD	TCGA;ICGC;COSMIC	5.915	Down-regulation
CMGC_MAPK_p38_MAPK14_ST	Q92945	KHSRP	Q16539	MAPK14	S480	G479R	479	Missense	proximal	-1	no	9.381	9.060	EPSD	TCGA;ICGC;COSMIC	5.915	Down-regulation
CMGC_MAPK_p38_MAPK14_ST	Q92945	KHSRP	Q16539	MAPK14	S480	P481S	481	Missense	proximal	1	no	9.381	2.097	EPSD	TCGA;ICGC;COSMIC	5.915	Loss
CMGC_MAPK_p38_MAPK14_ST	Q92945	KHSRP	Q16539	MAPK14	S480	R478W	478	Missense	proximal	-2	no	9.381	8.854	EPSD	TCGA;ICGC;COSMIC	5.915	Down-regulation
CMGC_MAPK_p38_MAPK14_ST	O43257	ZNHIT1	Q16539	MAPK14	T103	E97K	97	Missense	distal	-6	no	8.174	7.760	PhosphoSitePlus	TCGA;ICGC;COSMIC	5.915	Down-regulation
CMGC_MAPK_p38_MAPK14_ST	O43257	ZNHIT1	Q16539	MAPK14	T103	G107E	107	Missense	distal	4	no	8.174	8.906	PhosphoSitePlus	TCGA;ICGC;COSMIC	5.915	Up-regulation
CMGC_MAPK_p38_MAPK14_ST	O43257	ZNHIT1	Q16539	MAPK14	T103	S110L	110	Missense	distal	7	no	8.174	7.790	PhosphoSitePlus	TCGA;ICGC;COSMIC	5.915	Down-regulation
CMGC_MAPK_p38_MAPK14_ST	O43257	ZNHIT1	Q16539	MAPK14	T103	Y101C	101	Missense	proximal	-2	no	8.174	7.037	PhosphoSitePlus	TCGA;ICGC;COSMIC	5.915	Down-regulation
CMGC_MAPK_p38_MAPK14_ST	P05198	EIF2S1	Q16539	MAPK14	S52	M45I	45	Missense	distal	-7	no	7.729	7.324	PhosphoSitePlus	TCGA;ICGC;COSMIC	5.915	Down-regulation
CMGC_MAPK_p38_MAPK14_ST	P05198	EIF2S1	Q16539	MAPK14	S52	R57C	57	Missense	distal	5	no	7.729	6.859	PhosphoSitePlus	TCGA;ICGC;COSMIC	5.915	Down-regulation
CMGC_MAPK_p38_MAPK14_ST	P05198	EIF2S1	Q16539	MAPK14	S91	L85V	85	Missense	distal	-6	no	9.525	9.714	EPSD	TCGA;ICGC;COSMIC	5.915	Up-regulation
CMGC_MAPK_p38_MAPK14_ST	P05198	EIF2S1	Q16539	MAPK14	T185	R192Q	192	Missense	distal	7	no	11.316	11.122	EPSD	TCGA;ICGC;COSMIC	5.915	Down-regulation
CMGC_MAPK_p38_MAPK14_ST	P05198	EIF2S1	Q16539	MAPK14	T185	L184F	184	Missense	proximal	-1	no	11.316	11.280	EPSD	TCGA;ICGC;COSMIC	5.915	Down-regulation
CMGC_MAPK_p38_MAPK14_ST	Q13309	SKP2	Q16539	MAPK14	S64	L59R	59	Missense	distal	-5	no	9.493	8.983	PhosphoSitePlus	TCGA;ICGC;COSMIC	5.915	Down-regulation
CMGC_MAPK_p38_MAPK14_ST	Q13309	SKP2	Q16539	MAPK14	S179	S179G	179	Missense	central	0	yes	7.705	0.000	EPSD	TCGA;COSMIC	5.915	Loss
CMGC_MAPK_p38_MAPK14_ST	Q13309	SKP2	Q16539	MAPK14	S179	V183A	183	Missense	distal	4	no	7.705	8.139	EPSD	TCGA;ICGC	5.915	Up-regulation
CMGC_MAPK_p38_MAPK14_ST	Q13309	SKP2	Q16539	MAPK14	S179	Q184K	184	Missense	distal	5	no	7.705	7.760	EPSD	TCGA;ICGC;COSMIC	5.915	Up-regulation
CMGC_MAPK_p38_MAPK14_ST	Q13309	SKP2	Q16539	MAPK14	S179	R182C	182	Missense	distal	3	no	7.705	7.762	EPSD	TCGA;ICGC;COSMIC	5.915	Up-regulation
CMGC_MAPK_p38_MAPK14_ST	Q13309	SKP2	Q16539	MAPK14	S179	A175T	175	Missense	distal	-4	no	7.705	7.942	EPSD	TCGA;ICGC;COSMIC	5.915	Up-regulation
CMGC_MAPK_p38_MAPK14_ST	Q13309	SKP2	Q16539	MAPK14	S179	V183I	183	Missense	distal	4	no	7.705	7.656	EPSD	TCGA;ICGC;COSMIC	5.915	Down-regulation
CMGC_MAPK_p38_MAPK14_ST	Q13309	SKP2	Q16539	MAPK14	S179	Q172R	172	Missense	distal	-7	no	7.705	7.799	EPSD	TCGA;ICGC;COSMIC	5.915	Up-regulation
CMGC_MAPK_p38_MAPK14_ST	Q9H3M7	TXNIP	Q16539	MAPK14	T306	R305K	305	Missense	proximal	-1	no	6.507	6.588	EPSD	TCGA;ICGC;COSMIC	5.915	Up-regulation
CMGC_MAPK_p38_MAPK14_ST	Q9H3M7	TXNIP	Q16539	MAPK14	S307	R305K	305	Missense	proximal	-2	no	8.311	7.708	EPSD	TCGA;ICGC;COSMIC	5.915	Down-regulation
CMGC_MAPK_p38_MAPK14_ST	Q9H3M7	TXNIP	Q16539	MAPK14	S311	R305K	305	Missense	distal	-6	no	7.110	6.631	EPSD	TCGA;ICGC;COSMIC	5.915	Down-regulation
CMGC_MAPK_p38_MAPK14_ST	Q9H3M7	TXNIP	Q16539	MAPK14	S311	E316Q	316	Missense	distal	5	no	7.110	6.489	EPSD	TCGA;ICGC;COSMIC	5.915	Down-regulation
CMGC_MAPK_p38_MAPK14_ST	Q9H3M7	TXNIP	Q16539	MAPK14	S346	R343P	343	Missense	distal	-3	no	11.185	9.909	EPSD	TCGA;ICGC;COSMIC	5.915	Down-regulation
CMGC_MAPK_p38_MAPK14_ST	Q9H3M7	TXNIP	Q16539	MAPK14	S346	P339A	339	Missense	distal	-7	no	11.185	11.386	EPSD	TCGA;ICGC;COSMIC	5.915	Up-regulation
CMGC_MAPK_p38_MAPK14_ST	Q9H3M7	TXNIP	Q16539	MAPK14	S346	T349S	349	Missense	distal	3	no	11.185	11.172	EPSD	TCGA;ICGC;COSMIC	5.915	Down-regulation
CMGC_MAPK_p38_MAPK14_ST	Q9H3M7	TXNIP	Q16539	MAPK14	S346	P350H	350	Missense	distal	4	no	11.185	10.515	EPSD	TCGA;ICGC;COSMIC	5.915	Down-regulation
CMGC_MAPK_p38_MAPK14_ST	Q9H3M7	TXNIP	Q16539	MAPK14	T349	R343P	343	Missense	distal	-6	no	10.803	10.303	EPSD	TCGA;ICGC;COSMIC	5.915	Down-regulation
CMGC_MAPK_p38_MAPK14_ST	Q9H3M7	TXNIP	Q16539	MAPK14	T349	P350H	350	Missense	proximal	1	no	10.803	-2.850	EPSD	TCGA;ICGC;COSMIC	5.915	Loss
CMGC_MAPK_p38_MAPK14_ST	Q9H3M7	TXNIP	Q16539	MAPK14	S361	P368H	368	Missense	distal	7	no	10.642	10.365	PhosphoSitePlus	TCGA;ICGC;COSMIC	5.915	Down-regulation
CMGC_MAPK_p38_MAPK14_ST	P18850	ATF6	Q16539	MAPK14	S16	L23V	23	Missense	distal	7	no	10.902	11.200	EPSD	TCGA;ICGC;COSMIC	5.915	Up-regulation
CMGC_MAPK_p38_MAPK14_ST	P18850	ATF6	Q16539	MAPK14	S97	V102F	102	Missense	distal	5	no	5.934	5.149	EPSD	TCGA;ICGC;COSMIC	5.915	Loss
CMGC_MAPK_p38_MAPK14_ST	P18850	ATF6	Q16539	MAPK14	S104	V102F	102	Missense	proximal	-2	no	10.523	10.388	EPSD	TCGA;ICGC;COSMIC	5.915	Down-regulation
CMGC_MAPK_p38_MAPK14_ST	P18850	ATF6	Q16539	MAPK14	T166	K168T	168	Missense	proximal	2	no	8.902	9.016	PhosphoSitePlus	TCGA;ICGC;COSMIC	5.915	Up-regulation
CMGC_MAPK_p38_MAPK14_ST	P18850	ATF6	Q16539	MAPK14	T166	K168N	168	Missense	proximal	2	no	8.902	8.995	PhosphoSitePlus	TCGA;ICGC;COSMIC	5.915	Up-regulation
CMGC_MAPK_p38_MAPK14_ST	P18850	ATF6	Q16539	MAPK14	T166	E162K	162	Missense	distal	-4	no	8.902	9.127	PhosphoSitePlus	TCGA;ICGC;COSMIC	5.915	Up-regulation
CMGC_MAPK_p38_MAPK14_ST	P18850	ATF6	Q16539	MAPK14	S373	P374R	374	Missense	proximal	1	no	10.127	2.192	EPSD	TCGA;ICGC;COSMIC	5.915	Loss
CMGC_MAPK_p38_MAPK14_ST	P18850	ATF6	Q16539	MAPK14	S373	C380Y	380	Missense	distal	7	no	10.127	10.735	EPSD	TCGA;ICGC	5.915	Up-regulation
CMGC_MAPK_p38_MAPK14_ST	P18850	ATF6	Q16539	MAPK14	S410	M405T	405	Missense	distal	-5	no	8.308	8.596	EPSD	TCGA;ICGC	5.915	Up-regulation
Other_NAK_BIKE_AAK1_ST	P49757	NUMB	Q2M2I8	AAK1	T190	R196G	196	Missense	distal	6	no	2.432	2.512	EPSD	TCGA;ICGC;COSMIC	2.491	Gain
Other_NAK_BIKE_AAK1_ST	P49757	NUMB	Q2M2I8	AAK1	T190	R186Q	186	Missense	distal	-4	no	2.432	2.511	EPSD	TCGA;ICGC;COSMIC	2.491	Gain
Other_NAK_BIKE_AAK1_ST	P49757	NUMB	Q2M2I8	AAK1	T243	A236T	236	Missense	distal	-7	no	2.906	3.261	EPSD	TCGA;ICGC;COSMIC	2.491	Up-regulation
Other_NAK_BIKE_AAK1_ST	P49757	NUMB	Q2M2I8	AAK1	T243	A236V	236	Missense	distal	-7	no	2.906	3.115	EPSD	TCGA;ICGC;COSMIC	2.491	Up-regulation
Other_NAK_BIKE_AAK1_ST	P49757	NUMB	Q2M2I8	AAK1	T251	P258S	258	Missense	distal	7	no	3.014	3.013	EPSD	TCGA;ICGC;COSMIC	2.491	Down-regulation
Other_NAK_BIKE_AAK1_ST	P49757	NUMB	Q2M2I8	AAK1	S284	F277L	277	Missense	distal	-7	no	3.653	3.904	EPSD	TCGA;ICGC;COSMIC	2.491	Up-regulation
Other_NAK_BIKE_AAK1_ST	P49757	NUMB	Q2M2I8	AAK1	S284	K286N	286	Missense	proximal	2	no	3.653	3.787	EPSD	TCGA;ICGC;COSMIC	2.491	Up-regulation
Other_NAK_BIKE_AAK1_ST	P49757	NUMB	Q2M2I8	AAK1	T369	F364L	364	Missense	distal	-5	no	2.703	2.713	EPSD	TCGA;ICGC;COSMIC	2.491	Up-regulation
Other_NAK_BIKE_AAK1_ST	P49757	NUMB	Q2M2I8	AAK1	T369	F373C	373	Missense	distal	4	no	2.703	2.720	EPSD	TCGA;COSMIC	2.491	Up-regulation
Other_NAK_BIKE_AAK1_ST	P49757	NUMB	Q2M2I8	AAK1	T369	A372V	372	Missense	distal	3	no	2.703	2.750	EPSD	TCGA;ICGC	2.491	Up-regulation
Other_NAK_BIKE_AAK1_ST	P49757	NUMB	Q2M2I8	AAK1	T369	Q365R	365	Missense	distal	-4	no	2.703	2.624	EPSD	TCGA	2.491	Down-regulation
Other_NAK_BIKE_AAK1_ST	P49757	NUMB	Q2M2I8	AAK1	T631	S627F	627	Missense	distal	-4	no	3.039	2.976	EPSD	TCGA;COSMIC	2.491	Down-regulation
Other_NAK_BIKE_AAK1_ST	P49757	NUMB	Q2M2I8	AAK1	T631	R630H	630	Missense	proximal	-1	no	3.039	3.105	EPSD	TCGA;COSMIC;GDSC	2.491	Up-regulation
Other_NAK_BIKE_AAK1_ST	Q96CW1	AP2M1	Q2M2I8	AAK1	T134	A128T	128	Missense	distal	-6	no	2.496	2.567	EPSD	TCGA;ICGC;COSMIC	2.491	Up-regulation
Other_NAK_BIKE_AAK1_ST	Q96CW1	AP2M1	Q2M2I8	AAK1	T134	A128V	128	Missense	distal	-6	no	2.496	2.405	EPSD	TCGA;ICGC	2.491	Loss
Other_NAK_BIKE_AAK1_ST	Q96CW1	AP2M1	Q2M2I8	AAK1	T134	S140N	140	Missense	distal	6	no	2.496	2.430	EPSD	TCGA;ICGC;COSMIC	2.491	Loss
Other_NAK_BIKE_AAK1_ST	Q96CW1	AP2M1	Q2M2I8	AAK1	T156	R162Q	162	Missense	distal	6	no	9.991	9.965	PhosphoSitePlus	TCGA;COSMIC	2.491	Down-regulation
Other_NAK_BIKE_AAK1_ST	Q96CW1	AP2M1	Q2M2I8	AAK1	T156	Q150H	150	Missense	distal	-6	no	9.991	9.592	PhosphoSitePlus	TCGA;ICGC;COSMIC	2.491	Down-regulation
TK_Fer_FES_Y	P07332	FES	P07332	FES	Y261	R266Q	266	Missense	distal	5	no	8.730	9.013	EPSD	TCGA;GDSC;CCLE	7.476	Up-regulation
TK_Fer_FES_Y	P07332	FES	P07332	FES	Y261	R254G	254	Missense	distal	-7	no	8.730	8.791	EPSD	TCGA;COSMIC	7.476	Up-regulation
TK_Fer_FES_Y	P07332	FES	P07332	FES	Y261	R254H	254	Missense	distal	-7	no	8.730	8.692	EPSD	TCGA;ICGC;COSMIC;CCLE	7.476	Down-regulation
TK_Fer_FES_Y	P07332	FES	P07332	FES	Y713	R720I	720	Missense	distal	7	no	18.369	18.121	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	7.476	Down-regulation
TK_Fer_FES_Y	P07332	FES	P07332	FES	Y811	E813D	813	Missense	proximal	2	no	10.317	10.669	PhosphoSitePlus;EPSD	TCGA;ICGC;COSMIC	7.476	Up-regulation
TK_Fer_FES_Y	P07332	FES	P07332	FES	Y811	R818Q	818	Missense	distal	7	no	10.317	10.439	PhosphoSitePlus;EPSD	TCGA;COSMIC;GDSC;CCLE	7.476	Up-regulation
TK_Fer_FES_Y	P11274	BCR	P07332	FES	Y231	E237K	237	Missense	distal	6	no	7.323	7.507	EPSD	TCGA;ICGC;COSMIC	7.476	Gain
TK_Fer_FES_Y	P11274	BCR	P07332	FES	Y276	P270R	270	Missense	distal	-6	no	14.785	13.868	EPSD	TCGA;ICGC;COSMIC	7.476	Down-regulation
TK_Fer_FES_Y	P11274	BCR	P07332	FES	Y276	Y283C	283	Missense	distal	7	no	14.785	14.784	EPSD	TCGA;ICGC;COSMIC	7.476	Down-regulation
TK_Fer_FES_Y	P11274	BCR	P07332	FES	Y276	P269S	269	Missense	distal	-7	no	14.785	14.797	EPSD	TCGA;ICGC;COSMIC	7.476	Up-regulation
TK_Fer_FES_Y	P11274	BCR	P07332	FES	Y276	Q277R	277	Missense	proximal	1	no	14.785	12.061	EPSD	TCGA;ICGC;COSMIC	7.476	Down-regulation
TK_Fer_FES_Y	P11274	BCR	P07332	FES	Y276	P272S	272	Missense	distal	-4	no	14.785	14.764	EPSD	TCGA;ICGC;COSMIC	7.476	Down-regulation
TK_Fer_FES_Y	P11274	BCR	P07332	FES	Y279	Y283C	283	Missense	distal	4	no	16.933	16.879	EPSD	TCGA;ICGC;COSMIC	7.476	Down-regulation
TK_Fer_FES_Y	P11274	BCR	P07332	FES	Y279	Q277R	277	Missense	proximal	-2	no	16.933	15.913	EPSD	TCGA;ICGC;COSMIC	7.476	Down-regulation
TK_Fer_FES_Y	P11274	BCR	P07332	FES	Y279	P272S	272	Missense	distal	-7	no	16.933	16.945	EPSD	TCGA;ICGC;COSMIC	7.476	Up-regulation
TK_Fer_FES_Y	P11274	BCR	P07332	FES	Y283	Y283C	283	Missense	central	0	yes	15.668	0.000	EPSD	TCGA;ICGC;COSMIC	7.476	Loss
TK_Fer_FES_Y	P11274	BCR	P07332	FES	Y283	Q277R	277	Missense	distal	-6	no	15.668	14.195	EPSD	TCGA;ICGC;COSMIC	7.476	Down-regulation
TK_Fer_FES_Y	P11274	BCR	P07332	FES	Y283	M287V	287	Missense	distal	4	no	15.668	15.846	EPSD	TCGA;ICGC;COSMIC	7.476	Up-regulation
Other_IKK_CHUK_ST	Q9Y6Q9	NCOA3	O15111	CHUK	S101	T103A	103	Missense	proximal	2	no	189.644	190.033	EPSD	TCGA;ICGC;COSMIC	187.474	Up-regulation
Other_IKK_CHUK_ST	Q9Y6Q9	NCOA3	O15111	CHUK	S101	G106R	106	Missense	distal	5	no	189.644	192.050	EPSD	TCGA;ICGC;COSMIC	187.474	Up-regulation
Other_IKK_CHUK_ST	Q9Y6Q9	NCOA3	O15111	CHUK	S101	D99N	99	Missense	proximal	-2	no	189.644	188.845	EPSD	TCGA;ICGC;COSMIC	187.474	Down-regulation
Other_IKK_CHUK_ST	Q9Y6Q9	NCOA3	O15111	CHUK	S101	D94N	94	Missense	distal	-7	no	189.644	189.869	EPSD	TCGA;ICGC;COSMIC	187.474	Up-regulation
Other_IKK_CHUK_ST	Q9Y6Q9	NCOA3	O15111	CHUK	S214	A213G	213	Missense	proximal	-1	no	199.228	199.300	EPSD	TCGA;ICGC;COSMIC	187.474	Up-regulation
Other_IKK_CHUK_ST	Q9Y6Q9	NCOA3	O15111	CHUK	S214	A213V	213	Missense	proximal	-1	no	199.228	200.196	EPSD	TCGA;ICGC;COSMIC	187.474	Up-regulation
Other_IKK_CHUK_ST	Q9Y6Q9	NCOA3	O15111	CHUK	S288	D295V	295	Missense	distal	7	no	220.740	228.440	EPSD	TCGA;ICGC	187.474	Up-regulation
Other_IKK_CHUK_ST	Q9Y6Q9	NCOA3	O15111	CHUK	S288	G292V	292	Missense	distal	4	no	220.740	227.856	EPSD	TCGA;ICGC;COSMIC	187.474	Up-regulation
Other_IKK_CHUK_ST	Q9Y6Q9	NCOA3	O15111	CHUK	S306	G310W	310	Missense	distal	4	no	230.226	232.430	EPSD	TCGA;ICGC;COSMIC	187.474	Up-regulation
Other_IKK_CHUK_ST	Q9Y6Q9	NCOA3	O15111	CHUK	S628	S628F	628	Missense	central	0	yes	190.274	0.000	EPSD	TCGA;COSMIC	187.474	Loss
Other_IKK_CHUK_ST	Q9Y6Q9	NCOA3	O15111	CHUK	S640	K647R	647	Missense	distal	7	no	275.702	280.355	EPSD	TCGA;ICGC;COSMIC	187.474	Up-regulation
Other_IKK_CHUK_ST	Q9Y6Q9	NCOA3	O15111	CHUK	S640	S644L	644	Missense	distal	4	no	275.702	274.563	EPSD	TCGA;COSMIC	187.474	Down-regulation
Other_IKK_CHUK_ST	Q9Y6Q9	NCOA3	O15111	CHUK	S644	K647R	647	Missense	distal	3	no	208.303	175.165	EPSD	TCGA;ICGC;COSMIC	187.474	Loss
Other_IKK_CHUK_ST	Q9Y6Q9	NCOA3	O15111	CHUK	S644	S644L	644	Missense	central	0	yes	208.303	0.000	EPSD	TCGA;COSMIC	187.474	Loss
Other_IKK_CHUK_ST	Q9Y6Q9	NCOA3	O15111	CHUK	S662	S662C	662	Missense	central	0	yes	215.810	0.000	EPSD	TCGA;COSMIC	187.474	Loss
Other_IKK_CHUK_ST	Q9Y6Q9	NCOA3	O15111	CHUK	S662	S669C	669	Missense	distal	7	no	215.810	225.731	EPSD	TCGA;ICGC;COSMIC	187.474	Up-regulation
Other_IKK_CHUK_ST	Q9Y6Q9	NCOA3	O15111	CHUK	S715	D709Y	709	Missense	distal	-6	no	202.517	205.581	EPSD	TCGA;COSMIC	187.474	Up-regulation
Other_IKK_CHUK_ST	Q9Y6Q9	NCOA3	O15111	CHUK	S715	S715F	715	Missense	central	0	yes	202.517	0.000	EPSD	TCGA;COSMIC	187.474	Loss
Other_IKK_CHUK_ST	Q9Y6Q9	NCOA3	O15111	CHUK	S715	V721A	721	Missense	distal	6	no	202.517	195.003	EPSD	TCGA	187.474	Down-regulation
Other_IKK_CHUK_ST	Q9Y6Q9	NCOA3	O15111	CHUK	S857	R854Q	854	Missense	distal	-3	no	229.164	203.233	PhosphoSitePlus	TCGA;ICGC;COSMIC	187.474	Down-regulation
Other_IKK_CHUK_ST	Q9Y6Q9	NCOA3	O15111	CHUK	S916	P915S	915	Missense	proximal	-1	no	194.919	195.980	EPSD	TCGA;ICGC;COSMIC	187.474	Up-regulation
Other_IKK_CHUK_ST	Q9Y6Q9	NCOA3	O15111	CHUK	S1330	S1337L	1337	Missense	distal	7	no	194.924	196.060	EPSD	TCGA;COSMIC;GDSC;CCLE	187.474	Up-regulation
Other_IKK_CHUK_ST	Q9Y6Q9	NCOA3	O15111	CHUK	S1338	S1337L	1337	Missense	proximal	-1	no	202.883	203.814	EPSD	TCGA;COSMIC;GDSC;CCLE	187.474	Up-regulation
Other_IKK_CHUK_ST	Q9Y6Q9	NCOA3	O15111	CHUK	S1338	P1342S	1342	Missense	distal	4	no	202.883	204.813	EPSD	TCGA;ICGC;COSMIC	187.474	Up-regulation
Other_IKK_CHUK_ST	Q9Y6Q9	NCOA3	O15111	CHUK	S1338	R1339K	1339	Missense	proximal	1	no	202.883	214.489	EPSD	TCGA;COSMIC	187.474	Up-regulation
Other_IKK_CHUK_ST	Q9Y6Q9	NCOA3	O15111	CHUK	S1338	S1343F	1343	Missense	distal	5	no	202.883	209.709	EPSD	TCGA;ICGC;COSMIC	187.474	Up-regulation
Other_IKK_CHUK_ST	P19838	NFKB1	O15111	CHUK	S74	S74C	74	Missense	central	0	yes	243.762	0.000	EPSD	TCGA	187.474	Loss
Other_IKK_CHUK_ST	P19838	NFKB1	O15111	CHUK	S74	K79N	79	Missense	distal	5	no	243.762	240.141	EPSD	TCGA;COSMIC	187.474	Down-regulation
Other_IKK_CHUK_ST	P03372	ESR1	O15111	CHUK	S118	P113S	113	Missense	distal	-5	no	231.360	240.014	PhosphoSitePlus	TCGA;ICGC;COSMIC	187.474	Up-regulation
Other_IKK_CHUK_ST	P03372	ESR1	O15111	CHUK	S167	A166S	166	Missense	proximal	-1	no	203.246	204.893	EPSD	TCGA;ICGC;COSMIC	187.474	Up-regulation
Other_IKK_CHUK_ST	P03372	ESR1	O15111	CHUK	S167	K171M	171	Missense	distal	4	no	203.246	199.165	EPSD	TCGA;ICGC;COSMIC	187.474	Down-regulation
Other_IKK_CHUK_ST	P03372	ESR1	O15111	CHUK	S201	K206R	206	Missense	distal	5	no	213.048	212.732	EPSD	TCGA;ICGC;COSMIC	187.474	Down-regulation
Other_IKK_CHUK_ST	P03372	ESR1	O15111	CHUK	S201	Y197C	197	Missense	distal	-4	no	213.048	198.300	EPSD	TCGA;ICGC;COSMIC	187.474	Down-regulation
Other_IKK_CHUK_ST	P03372	ESR1	O15111	CHUK	S201	H196R	196	Missense	distal	-5	no	213.048	208.163	EPSD	TCGA;ICGC;COSMIC	187.474	Down-regulation
Other_IKK_CHUK_ST	P03372	ESR1	O15111	CHUK	S201	A207T	207	Missense	distal	6	no	213.048	208.328	EPSD	TCGA;ICGC;COSMIC	187.474	Down-regulation
Other_IKK_CHUK_ST	P03372	ESR1	O15111	CHUK	S236	A239S	239	Missense	distal	3	no	161.705	199.758	EPSD	TCGA;ICGC;COSMIC	187.474	Gain
Other_IKK_CHUK_ST	P03372	ESR1	O15111	CHUK	S341	P336T	336	Missense	distal	-5	no	209.841	212.814	EPSD	TCGA;ICGC;COSMIC	187.474	Up-regulation
Other_IKK_CHUK_ST	P03372	ESR1	O15111	CHUK	S341	G344D	344	Missense	distal	3	no	209.841	237.580	EPSD	TCGA;ICGC;COSMIC	187.474	Up-regulation
Other_IKK_CHUK_ST	P03372	ESR1	O15111	CHUK	S573	S575L	575	Missense	proximal	2	no	190.752	190.419	EPSD	TCGA;ICGC;COSMIC	187.474	Down-regulation
Other_IKK_CHUK_ST	P03372	ESR1	O15111	CHUK	S575	S575L	575	Missense	central	0	yes	204.263	0.000	EPSD	TCGA;ICGC;COSMIC	187.474	Loss
Other_IKK_CHUK_ST	P03372	ESR1	O15111	CHUK	S575	K581T	581	Missense	distal	6	no	204.263	194.894	EPSD	TCGA;ICGC	187.474	Down-regulation
Other_IKK_CHUK_ST	P03372	ESR1	O15111	CHUK	S578	T585M	585	Missense	distal	7	no	220.288	217.538	EPSD	TCGA;ICGC;COSMIC	187.474	Down-regulation
Other_IKK_CHUK_ST	P03372	ESR1	O15111	CHUK	S578	S575L	575	Missense	distal	-3	no	220.288	224.052	EPSD	TCGA;ICGC;COSMIC	187.474	Up-regulation
Other_IKK_CHUK_ST	P03372	ESR1	O15111	CHUK	S578	K581T	581	Missense	distal	3	no	220.288	221.817	EPSD	TCGA;ICGC	187.474	Up-regulation
Other_IKK_CHUK_ST	Q9BUZ4	TRAF4	O15111	CHUK	S242	L239V	239	Missense	distal	-3	no	174.689	190.420	EPSD	TCGA;ICGC;COSMIC	187.474	Gain
Other_IKK_CHUK_ST	Q9BUZ4	TRAF4	O15111	CHUK	S426	E429G	429	Missense	distal	3	no	230.698	248.725	PhosphoSitePlus	TCGA;COSMIC	187.474	Up-regulation
Other_IKK_CHUK_ST	Q9BUZ4	TRAF4	O15111	CHUK	S426	R424W	424	Missense	proximal	-2	no	230.698	215.046	PhosphoSitePlus	TCGA;ICGC;COSMIC;GDSC	187.474	Down-regulation
Other_IKK_CHUK_ST	P25963	NFKBIA	O15111	CHUK	S32	D31N	31	Missense	proximal	-1	no	241.183	238.283	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	187.474	Down-regulation
Other_IKK_CHUK_ST	P25963	NFKBIA	O15111	CHUK	S32	D27H	27	Missense	distal	-5	no	241.183	221.481	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	187.474	Down-regulation
Other_IKK_CHUK_ST	P25963	NFKBIA	O15111	CHUK	S36	E41K	41	Missense	distal	5	no	284.901	283.236	PhosphoSitePlus;EPSD	TCGA;ICGC	187.474	Down-regulation
Other_IKK_CHUK_ST	P25963	NFKBIA	O15111	CHUK	S36	D31N	31	Missense	distal	-5	no	284.901	266.853	PhosphoSitePlus;EPSD	TCGA;ICGC;COSMIC	187.474	Down-regulation
Other_IKK_CHUK_ST	P25963	NFKBIA	O15111	CHUK	S36	Y42C	42	Missense	distal	6	no	284.901	291.143	PhosphoSitePlus;EPSD	TCGA;ICGC;COSMIC	187.474	Up-regulation
Other_IKK_CHUK_ST	P25963	NFKBIA	O15111	CHUK	S174	S174P	174	Missense	central	0	yes	218.059	0.000	EPSD	TCGA;COSMIC	187.474	Loss
Other_IKK_CHUK_ST	P25963	NFKBIA	O15111	CHUK	S293	D290G	290	Missense	distal	-3	no	198.244	207.293	EPSD	TCGA	187.474	Up-regulation
Other_IKK_CHUK_ST	Q00653	NFKB2	O15111	CHUK	S70	G64R	64	Missense	distal	-6	no	225.266	230.319	EPSD	TCGA;ICGC;COSMIC	187.474	Up-regulation
Other_IKK_CHUK_ST	Q00653	NFKB2	O15111	CHUK	S70	R74G	74	Missense	distal	4	no	225.266	218.399	EPSD	TCGA;ICGC;COSMIC	187.474	Down-regulation
Other_IKK_CHUK_ST	Q00653	NFKB2	O15111	CHUK	S99	R103C	103	Missense	distal	4	no	219.724	213.037	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	187.474	Down-regulation
Other_IKK_CHUK_ST	Q00653	NFKB2	O15111	CHUK	S108	S115L	115	Missense	distal	7	no	258.479	259.616	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	187.474	Up-regulation
Other_IKK_CHUK_ST	Q00653	NFKB2	O15111	CHUK	S108	R103C	103	Missense	distal	-5	no	258.479	257.631	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	187.474	Down-regulation
Other_IKK_CHUK_ST	Q00653	NFKB2	O15111	CHUK	S115	S115L	115	Missense	central	0	yes	232.404	0.000	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	187.474	Loss
Other_IKK_CHUK_ST	Q00653	NFKB2	O15111	CHUK	S123	S123F	123	Missense	central	0	yes	233.539	0.000	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	187.474	Loss
Other_IKK_CHUK_ST	Q00653	NFKB2	O15111	CHUK	S231	G224E	224	Missense	distal	-7	no	210.317	208.089	EPSD	TCGA;ICGC;COSMIC	187.474	Down-regulation
Other_IKK_CHUK_ST	Q00653	NFKB2	O15111	CHUK	S231	S231Y	231	Missense	central	0	yes	210.317	0.000	EPSD	TCGA;ICGC	187.474	Loss
Other_IKK_CHUK_ST	Q00653	NFKB2	O15111	CHUK	S231	K235N	235	Missense	distal	4	no	210.317	208.995	EPSD	TCGA;ICGC	187.474	Down-regulation
Other_IKK_CHUK_ST	Q00653	NFKB2	O15111	CHUK	S239	G243E	243	Missense	distal	4	no	243.078	246.058	EPSD	TCGA;ICGC;COSMIC	187.474	Up-regulation
Other_IKK_CHUK_ST	Q00653	NFKB2	O15111	CHUK	S239	R241W	241	Missense	proximal	2	no	243.078	247.233	EPSD	TCGA;ICGC;COSMIC	187.474	Up-regulation
Other_IKK_CHUK_ST	Q00653	NFKB2	O15111	CHUK	S239	K235N	235	Missense	distal	-4	no	243.078	254.429	EPSD	TCGA;ICGC	187.474	Up-regulation
Other_IKK_CHUK_ST	Q00653	NFKB2	O15111	CHUK	S277	S277F	277	Missense	central	0	yes	199.977	0.000	EPSD	TCGA;ICGC;COSMIC	187.474	Loss
Other_IKK_CHUK_ST	Q00653	NFKB2	O15111	CHUK	S277	P278L	278	Missense	proximal	1	no	199.977	214.051	EPSD	TCGA;ICGC;COSMIC	187.474	Up-regulation
Other_IKK_CHUK_ST	Q00653	NFKB2	O15111	CHUK	S277	D280V	280	Missense	distal	3	no	199.977	121.648	EPSD	TCGA;ICGC;COSMIC	187.474	Loss
Other_IKK_CHUK_ST	Q00653	NFKB2	O15111	CHUK	S769	D772G	772	Missense	distal	3	no	217.882	190.143	EPSD	TCGA;ICGC;COSMIC	187.474	Down-regulation
Other_IKK_CHUK_ST	Q00653	NFKB2	O15111	CHUK	S769	D772H	772	Missense	distal	3	no	217.882	165.828	EPSD	TCGA;ICGC;COSMIC	187.474	Loss
Other_IKK_CHUK_ST	Q00653	NFKB2	O15111	CHUK	S769	G767A	767	Missense	proximal	-2	no	217.882	253.819	EPSD	TCGA;ICGC;COSMIC	187.474	Up-regulation
Other_IKK_CHUK_ST	Q00653	NFKB2	O15111	CHUK	S812	G815D	815	Missense	distal	3	no	194.115	221.854	EPSD	TCGA;ICGC;COSMIC	187.474	Up-regulation
Other_IKK_CHUK_ST	Q00653	NFKB2	O15111	CHUK	S814	G815D	815	Missense	proximal	1	no	200.595	208.677	EPSD	TCGA;ICGC;COSMIC	187.474	Up-regulation
Other_IKK_CHUK_ST	Q01201	RELB	O15111	CHUK	S116	A118V	118	Missense	proximal	2	no	228.504	229.021	EPSD	TCGA;COSMIC	187.474	Up-regulation
Other_IKK_CHUK_ST	Q01201	RELB	O15111	CHUK	S116	P110L	110	Missense	distal	-6	no	228.504	220.596	EPSD	TCGA;COSMIC	187.474	Down-regulation
Other_IKK_CHUK_ST	Q01201	RELB	O15111	CHUK	S151	G154A	154	Missense	distal	3	no	254.845	204.872	EPSD	TCGA;COSMIC	187.474	Down-regulation
Other_IKK_CHUK_ST	Q01201	RELB	O15111	CHUK	S151	S148L	148	Missense	distal	-3	no	254.845	258.609	EPSD	TCGA;COSMIC	187.474	Up-regulation
Other_IKK_CHUK_ST	Q01201	RELB	O15111	CHUK	S151	L153F	153	Missense	proximal	2	no	254.845	254.930	EPSD	TCGA;COSMIC	187.474	Up-regulation
Other_IKK_CHUK_ST	Q01201	RELB	O15111	CHUK	S151	R147C	147	Missense	distal	-4	no	254.845	246.568	EPSD	TCGA;COSMIC	187.474	Down-regulation
Other_IKK_CHUK_ST	Q01201	RELB	O15111	CHUK	S472	S468C	468	Missense	distal	-4	no	230.199	202.672	PhosphoSitePlus	TCGA;ICGC;COSMIC	187.474	Down-regulation
Other_IKK_CHUK_ST	Q01201	RELB	O15111	CHUK	S472	D465E	465	Missense	distal	-7	no	230.199	227.348	PhosphoSitePlus	TCGA;COSMIC	187.474	Down-regulation
Other_IKK_CHUK_ST	Q01201	RELB	O15111	CHUK	S472	P479S	479	Missense	distal	7	no	230.199	223.534	PhosphoSitePlus	TCGA;COSMIC	187.474	Down-regulation
Other_IKK_CHUK_ST	Q01201	RELB	O15111	CHUK	S472	G469D	469	Missense	distal	-3	no	230.199	221.149	PhosphoSitePlus	TCGA;COSMIC	187.474	Down-regulation
Other_IKK_CHUK_ST	Q01201	RELB	O15111	CHUK	S573	A566V	566	Missense	distal	-7	no	224.036	223.512	EPSD	TCGA;ICGC;COSMIC	187.474	Down-regulation
Other_IKK_CHUK_ST	Q676U5	ATG16L1	O15111	CHUK	S278	S278Y	278	Missense	central	0	yes	257.874	0.000	PhosphoSitePlus	TCGA;ICGC;COSMIC	187.474	Loss
Other_IKK_CHUK_ST	Q676U5	ATG16L1	O15111	CHUK	S287	R286H	286	Missense	proximal	-1	no	186.604	187.850	EPSD	TCGA;COSMIC	187.474	Gain
Other_IKK_CHUK_ST	P35222	CTNNB1	O15111	CHUK	S29	G34R	34	Missense	distal	5	no	194.361	196.768	EPSD	TCGA;COSMIC	187.474	Up-regulation
Other_IKK_CHUK_ST	P35222	CTNNB1	O15111	CHUK	S29	G34V	34	Missense	distal	5	no	194.361	197.496	EPSD	TCGA;COSMIC;CCLE	187.474	Up-regulation
Other_IKK_CHUK_ST	P35222	CTNNB1	O15111	CHUK	S29	G34E	34	Missense	distal	5	no	194.361	198.749	EPSD	TCGA;COSMIC;GDSC;CCLE	187.474	Up-regulation
Other_IKK_CHUK_ST	P35222	CTNNB1	O15111	CHUK	S29	S33F	33	Missense	distal	4	no	194.361	192.700	EPSD	TCGA;COSMIC;GDSC;CCLE	187.474	Down-regulation
Other_IKK_CHUK_ST	P35222	CTNNB1	O15111	CHUK	S29	D32H	32	Missense	distal	3	no	194.361	142.307	EPSD	TCGA;COSMIC	187.474	Loss
Other_IKK_CHUK_ST	P35222	CTNNB1	O15111	CHUK	S29	D32G	32	Missense	distal	3	no	194.361	166.622	EPSD	TCGA;COSMIC	187.474	Loss
Other_IKK_CHUK_ST	P35222	CTNNB1	O15111	CHUK	S29	S33A	33	Missense	distal	4	no	194.361	188.453	EPSD	TCGA;COSMIC	187.474	Down-regulation
Other_IKK_CHUK_ST	P35222	CTNNB1	O15111	CHUK	S29	S33Y	33	Missense	distal	4	no	194.361	189.094	EPSD	TCGA;COSMIC;GDSC;CCLE	187.474	Down-regulation
Other_IKK_CHUK_ST	P35222	CTNNB1	O15111	CHUK	S29	D32V	32	Missense	distal	3	no	194.361	116.032	EPSD	TCGA;COSMIC;CCLE	187.474	Loss
Other_IKK_CHUK_ST	P35222	CTNNB1	O15111	CHUK	S29	S33P	33	Missense	distal	4	no	194.361	192.432	EPSD	TCGA;COSMIC;CCLE	187.474	Down-regulation
Other_IKK_CHUK_ST	P35222	CTNNB1	O15111	CHUK	S29	H36P	36	Missense	distal	7	no	194.361	192.692	EPSD	TCGA;COSMIC;CCLE	187.474	Down-regulation
Other_IKK_CHUK_ST	P35222	CTNNB1	O15111	CHUK	S29	D32Y	32	Missense	distal	3	no	194.361	139.082	EPSD	TCGA;COSMIC;CCLE	187.474	Loss
Other_IKK_CHUK_ST	P35222	CTNNB1	O15111	CHUK	S29	I35S	35	Missense	distal	6	no	194.361	193.105	EPSD	TCGA;COSMIC	187.474	Down-regulation
Other_IKK_CHUK_ST	P35222	CTNNB1	O15111	CHUK	S29	S33C	33	Missense	distal	4	no	194.361	186.147	EPSD	TCGA;COSMIC;GDSC;CCLE	187.474	Loss
Other_IKK_CHUK_ST	P35222	CTNNB1	O15111	CHUK	S29	D32N	32	Missense	distal	3	no	194.361	157.401	EPSD	TCGA;COSMIC;CCLE	187.474	Loss
Other_IKK_CHUK_ST	P35222	CTNNB1	O15111	CHUK	S29	S33T	33	Missense	distal	4	no	194.361	191.140	EPSD	TCGA;COSMIC	187.474	Down-regulation
Other_IKK_CHUK_ST	P35222	CTNNB1	O15111	CHUK	S29	D32A	32	Missense	distal	3	no	194.361	116.650	EPSD	TCGA;COSMIC	187.474	Loss
Other_IKK_CHUK_ST	P35222	CTNNB1	O15111	CHUK	S33	G34R	34	Missense	proximal	1	no	216.077	209.755	EPSD;PhosphoSitePlus	TCGA;COSMIC	187.474	Down-regulation
Other_IKK_CHUK_ST	P35222	CTNNB1	O15111	CHUK	S33	G34V	34	Missense	proximal	1	no	216.077	229.204	EPSD;PhosphoSitePlus	TCGA;COSMIC;CCLE	187.474	Up-regulation
Other_IKK_CHUK_ST	P35222	CTNNB1	O15111	CHUK	S33	G34E	34	Missense	proximal	1	no	216.077	229.061	EPSD;PhosphoSitePlus	TCGA;COSMIC;GDSC;CCLE	187.474	Up-regulation
Other_IKK_CHUK_ST	P35222	CTNNB1	O15111	CHUK	S33	S37C	37	Missense	distal	4	no	216.077	207.863	EPSD;PhosphoSitePlus	TCGA;COSMIC;GDSC;CCLE	187.474	Down-regulation
Other_IKK_CHUK_ST	P35222	CTNNB1	O15111	CHUK	S33	S37F	37	Missense	distal	4	no	216.077	214.416	EPSD;PhosphoSitePlus	TCGA;COSMIC;GDSC;CCLE	187.474	Down-regulation
Other_IKK_CHUK_ST	P35222	CTNNB1	O15111	CHUK	S33	S33F	33	Missense	central	0	yes	216.077	0.000	EPSD;PhosphoSitePlus	TCGA;COSMIC;GDSC;CCLE	187.474	Loss
Other_IKK_CHUK_ST	P35222	CTNNB1	O15111	CHUK	S33	D32H	32	Missense	proximal	-1	no	216.077	213.529	EPSD;PhosphoSitePlus	TCGA;COSMIC	187.474	Down-regulation
Other_IKK_CHUK_ST	P35222	CTNNB1	O15111	CHUK	S33	D32G	32	Missense	proximal	-1	no	216.077	212.326	EPSD;PhosphoSitePlus	TCGA;COSMIC	187.474	Down-regulation
Other_IKK_CHUK_ST	P35222	CTNNB1	O15111	CHUK	S33	S33A	33	Missense	central	0	yes	216.077	0.000	EPSD;PhosphoSitePlus	TCGA;COSMIC	187.474	Loss
Other_IKK_CHUK_ST	P35222	CTNNB1	O15111	CHUK	S33	S33Y	33	Missense	central	0	yes	216.077	0.000	EPSD;PhosphoSitePlus	TCGA;COSMIC;GDSC;CCLE	187.474	Loss
Other_IKK_CHUK_ST	P35222	CTNNB1	O15111	CHUK	S33	D32V	32	Missense	proximal	-1	no	216.077	213.223	EPSD;PhosphoSitePlus	TCGA;COSMIC;CCLE	187.474	Down-regulation
Other_IKK_CHUK_ST	P35222	CTNNB1	O15111	CHUK	S33	S33P	33	Missense	central	0	yes	216.077	0.000	EPSD;PhosphoSitePlus	TCGA;COSMIC;CCLE	187.474	Loss
Other_IKK_CHUK_ST	P35222	CTNNB1	O15111	CHUK	S33	H36P	36	Missense	distal	3	no	216.077	230.049	EPSD;PhosphoSitePlus	TCGA;COSMIC;CCLE	187.474	Up-regulation
Other_IKK_CHUK_ST	P35222	CTNNB1	O15111	CHUK	S33	D32Y	32	Missense	proximal	-1	no	216.077	213.166	EPSD;PhosphoSitePlus	TCGA;COSMIC;CCLE	187.474	Down-regulation
Other_IKK_CHUK_ST	P35222	CTNNB1	O15111	CHUK	S33	I35S	35	Missense	proximal	2	no	216.077	214.810	EPSD;PhosphoSitePlus	TCGA;COSMIC	187.474	Down-regulation
Other_IKK_CHUK_ST	P35222	CTNNB1	O15111	CHUK	S33	S37Y	37	Missense	distal	4	no	216.077	210.810	EPSD;PhosphoSitePlus	TCGA;COSMIC	187.474	Down-regulation
Other_IKK_CHUK_ST	P35222	CTNNB1	O15111	CHUK	S33	S33C	33	Missense	central	0	yes	216.077	0.000	EPSD;PhosphoSitePlus	TCGA;COSMIC;GDSC;CCLE	187.474	Loss
Other_IKK_CHUK_ST	P35222	CTNNB1	O15111	CHUK	S33	S37A	37	Missense	distal	4	no	216.077	210.168	EPSD;PhosphoSitePlus	TCGA;COSMIC;GDSC;CCLE	187.474	Down-regulation
Other_IKK_CHUK_ST	P35222	CTNNB1	O15111	CHUK	S33	D32N	32	Missense	proximal	-1	no	216.077	213.177	EPSD;PhosphoSitePlus	TCGA;COSMIC;CCLE	187.474	Down-regulation
Other_IKK_CHUK_ST	P35222	CTNNB1	O15111	CHUK	S33	S37P	37	Missense	distal	4	no	216.077	214.147	EPSD;PhosphoSitePlus	TCGA;COSMIC;GDSC;CCLE	187.474	Down-regulation
Other_IKK_CHUK_ST	P35222	CTNNB1	O15111	CHUK	S33	D32A	32	Missense	proximal	-1	no	216.077	212.254	EPSD;PhosphoSitePlus	TCGA;COSMIC	187.474	Down-regulation
Other_IKK_CHUK_ST	P35222	CTNNB1	O15111	CHUK	S37	G34R	34	Missense	distal	-3	no	235.061	240.030	PhosphoSitePlus;EPSD	TCGA;COSMIC	187.474	Up-regulation
Other_IKK_CHUK_ST	P35222	CTNNB1	O15111	CHUK	S37	G34V	34	Missense	distal	-3	no	235.061	240.548	PhosphoSitePlus;EPSD	TCGA;COSMIC;CCLE	187.474	Up-regulation
Other_IKK_CHUK_ST	P35222	CTNNB1	O15111	CHUK	S37	T41A	41	Missense	distal	4	no	235.061	232.374	PhosphoSitePlus;EPSD	TCGA;COSMIC;GDSC;CCLE	187.474	Down-regulation
Other_IKK_CHUK_ST	P35222	CTNNB1	O15111	CHUK	S37	G34E	34	Missense	distal	-3	no	235.061	225.874	PhosphoSitePlus;EPSD	TCGA;COSMIC;GDSC;CCLE	187.474	Down-regulation
Other_IKK_CHUK_ST	P35222	CTNNB1	O15111	CHUK	S37	S37C	37	Missense	central	0	yes	235.061	0.000	PhosphoSitePlus;EPSD	TCGA;COSMIC;GDSC;CCLE	187.474	Loss
Other_IKK_CHUK_ST	P35222	CTNNB1	O15111	CHUK	S37	S37F	37	Missense	central	0	yes	235.061	0.000	PhosphoSitePlus;EPSD	TCGA;COSMIC;GDSC;CCLE	187.474	Loss
Other_IKK_CHUK_ST	P35222	CTNNB1	O15111	CHUK	S37	S33F	33	Missense	distal	-4	no	235.061	207.391	PhosphoSitePlus;EPSD	TCGA;COSMIC;GDSC;CCLE	187.474	Down-regulation
Other_IKK_CHUK_ST	P35222	CTNNB1	O15111	CHUK	S37	D32H	32	Missense	distal	-5	no	235.061	215.358	PhosphoSitePlus;EPSD	TCGA;COSMIC	187.474	Down-regulation
Other_IKK_CHUK_ST	P35222	CTNNB1	O15111	CHUK	S37	D32G	32	Missense	distal	-5	no	235.061	214.462	PhosphoSitePlus;EPSD	TCGA;COSMIC	187.474	Down-regulation
Other_IKK_CHUK_ST	P35222	CTNNB1	O15111	CHUK	S37	T41I	41	Missense	distal	4	no	235.061	238.408	PhosphoSitePlus;EPSD	TCGA;COSMIC	187.474	Up-regulation
Other_IKK_CHUK_ST	P35222	CTNNB1	O15111	CHUK	S37	S33A	33	Missense	distal	-4	no	235.061	218.567	PhosphoSitePlus;EPSD	TCGA;COSMIC	187.474	Down-regulation
Other_IKK_CHUK_ST	P35222	CTNNB1	O15111	CHUK	S37	S33Y	33	Missense	distal	-4	no	235.061	222.282	PhosphoSitePlus;EPSD	TCGA;COSMIC;GDSC;CCLE	187.474	Down-regulation
Other_IKK_CHUK_ST	P35222	CTNNB1	O15111	CHUK	S37	D32V	32	Missense	distal	-5	no	235.061	211.012	PhosphoSitePlus;EPSD	TCGA;COSMIC;CCLE	187.474	Down-regulation
Other_IKK_CHUK_ST	P35222	CTNNB1	O15111	CHUK	S37	S33P	33	Missense	distal	-4	no	235.061	227.443	PhosphoSitePlus;EPSD	TCGA;COSMIC;CCLE	187.474	Down-regulation
Other_IKK_CHUK_ST	P35222	CTNNB1	O15111	CHUK	S37	H36P	36	Missense	proximal	-1	no	235.061	234.372	PhosphoSitePlus;EPSD	TCGA;COSMIC;CCLE	187.474	Down-regulation
Other_IKK_CHUK_ST	P35222	CTNNB1	O15111	CHUK	S37	D32Y	32	Missense	distal	-5	no	235.061	220.045	PhosphoSitePlus;EPSD	TCGA;COSMIC;CCLE	187.474	Down-regulation
Other_IKK_CHUK_ST	P35222	CTNNB1	O15111	CHUK	S37	I35S	35	Missense	proximal	-2	no	235.061	226.767	PhosphoSitePlus;EPSD	TCGA;COSMIC	187.474	Down-regulation
Other_IKK_CHUK_ST	P35222	CTNNB1	O15111	CHUK	S37	S37Y	37	Missense	central	0	yes	235.061	0.000	PhosphoSitePlus;EPSD	TCGA;COSMIC	187.474	Loss
Other_IKK_CHUK_ST	P35222	CTNNB1	O15111	CHUK	S37	S33C	33	Missense	distal	-4	no	235.061	207.534	PhosphoSitePlus;EPSD	TCGA;COSMIC;GDSC;CCLE	187.474	Down-regulation
Other_IKK_CHUK_ST	P35222	CTNNB1	O15111	CHUK	S37	S37A	37	Missense	central	0	yes	235.061	0.000	PhosphoSitePlus;EPSD	TCGA;COSMIC;GDSC;CCLE	187.474	Loss
Other_IKK_CHUK_ST	P35222	CTNNB1	O15111	CHUK	S37	D32N	32	Missense	distal	-5	no	235.061	217.013	PhosphoSitePlus;EPSD	TCGA;COSMIC;CCLE	187.474	Down-regulation
Other_IKK_CHUK_ST	P35222	CTNNB1	O15111	CHUK	S37	S33T	33	Missense	distal	-4	no	235.061	217.691	PhosphoSitePlus;EPSD	TCGA;COSMIC	187.474	Down-regulation
Other_IKK_CHUK_ST	P35222	CTNNB1	O15111	CHUK	S37	T41N	41	Missense	distal	4	no	235.061	236.870	PhosphoSitePlus;EPSD	TCGA;COSMIC	187.474	Up-regulation
Other_IKK_CHUK_ST	P35222	CTNNB1	O15111	CHUK	S37	S37P	37	Missense	central	0	yes	235.061	0.000	PhosphoSitePlus;EPSD	TCGA;COSMIC;GDSC;CCLE	187.474	Loss
Other_IKK_CHUK_ST	P35222	CTNNB1	O15111	CHUK	S37	D32A	32	Missense	distal	-5	no	235.061	211.591	PhosphoSitePlus;EPSD	TCGA;COSMIC	187.474	Down-regulation
Other_IKK_CHUK_ST	P35222	CTNNB1	O15111	CHUK	T41	S45F	45	Missense	distal	4	no	218.452	216.791	EPSD;PhosphoSitePlus	TCGA;COSMIC;GDSC;CCLE	187.474	Down-regulation
Other_IKK_CHUK_ST	P35222	CTNNB1	O15111	CHUK	T41	G34R	34	Missense	distal	-7	no	218.452	214.599	EPSD;PhosphoSitePlus	TCGA;COSMIC	187.474	Down-regulation
Other_IKK_CHUK_ST	P35222	CTNNB1	O15111	CHUK	T41	S45P	45	Missense	distal	4	no	218.452	216.522	EPSD;PhosphoSitePlus	TCGA;COSMIC;CCLE	187.474	Down-regulation
Other_IKK_CHUK_ST	P35222	CTNNB1	O15111	CHUK	T41	G34V	34	Missense	distal	-7	no	218.452	215.313	EPSD;PhosphoSitePlus	TCGA;COSMIC;CCLE	187.474	Down-regulation
Other_IKK_CHUK_ST	P35222	CTNNB1	O15111	CHUK	T41	T41A	41	Missense	central	0	yes	218.452	0.000	EPSD;PhosphoSitePlus	TCGA;COSMIC;GDSC;CCLE	187.474	Loss
Other_IKK_CHUK_ST	P35222	CTNNB1	O15111	CHUK	T41	G34E	34	Missense	distal	-7	no	218.452	216.224	EPSD;PhosphoSitePlus	TCGA;COSMIC;GDSC;CCLE	187.474	Down-regulation
Other_IKK_CHUK_ST	P35222	CTNNB1	O15111	CHUK	T41	S37C	37	Missense	distal	-4	no	218.452	190.925	EPSD;PhosphoSitePlus	TCGA;COSMIC;GDSC;CCLE	187.474	Down-regulation
Other_IKK_CHUK_ST	P35222	CTNNB1	O15111	CHUK	T41	S37F	37	Missense	distal	-4	no	218.452	190.783	EPSD;PhosphoSitePlus	TCGA;COSMIC;GDSC;CCLE	187.474	Down-regulation
Other_IKK_CHUK_ST	P35222	CTNNB1	O15111	CHUK	T41	T41I	41	Missense	central	0	yes	218.452	0.000	EPSD;PhosphoSitePlus	TCGA;COSMIC	187.474	Loss
Other_IKK_CHUK_ST	P35222	CTNNB1	O15111	CHUK	T41	S45Y	45	Missense	distal	4	no	218.452	213.184	EPSD;PhosphoSitePlus	TCGA;COSMIC	187.474	Down-regulation
Other_IKK_CHUK_ST	P35222	CTNNB1	O15111	CHUK	T41	H36P	36	Missense	distal	-5	no	218.452	221.292	EPSD;PhosphoSitePlus	TCGA;COSMIC;CCLE	187.474	Up-regulation
Other_IKK_CHUK_ST	P35222	CTNNB1	O15111	CHUK	T41	I35S	35	Missense	distal	-6	no	218.452	215.840	EPSD;PhosphoSitePlus	TCGA;COSMIC	187.474	Down-regulation
Other_IKK_CHUK_ST	P35222	CTNNB1	O15111	CHUK	T41	S37Y	37	Missense	distal	-4	no	218.452	205.673	EPSD;PhosphoSitePlus	TCGA;COSMIC	187.474	Down-regulation
Other_IKK_CHUK_ST	P35222	CTNNB1	O15111	CHUK	T41	S37A	37	Missense	distal	-4	no	218.452	201.958	EPSD;PhosphoSitePlus	TCGA;COSMIC;GDSC;CCLE	187.474	Down-regulation
Other_IKK_CHUK_ST	P35222	CTNNB1	O15111	CHUK	T41	T41N	41	Missense	central	0	yes	218.452	0.000	EPSD;PhosphoSitePlus	TCGA;COSMIC	187.474	Loss
Other_IKK_CHUK_ST	P35222	CTNNB1	O15111	CHUK	T41	S45C	45	Missense	distal	4	no	218.452	210.238	EPSD;PhosphoSitePlus	TCGA;COSMIC;GDSC;CCLE	187.474	Down-regulation
Other_IKK_CHUK_ST	P35222	CTNNB1	O15111	CHUK	T41	S37P	37	Missense	distal	-4	no	218.452	210.835	EPSD;PhosphoSitePlus	TCGA;COSMIC;GDSC;CCLE	187.474	Down-regulation
Other_IKK_CHUK_ST	P35222	CTNNB1	O15111	CHUK	S45	S45F	45	Missense	central	0	yes	247.229	0.000	EPSD;PhosphoSitePlus	TCGA;COSMIC;GDSC;CCLE	187.474	Loss
Other_IKK_CHUK_ST	P35222	CTNNB1	O15111	CHUK	S45	S45P	45	Missense	central	0	yes	247.229	0.000	EPSD;PhosphoSitePlus	TCGA;COSMIC;CCLE	187.474	Loss
Other_IKK_CHUK_ST	P35222	CTNNB1	O15111	CHUK	S45	T41A	41	Missense	distal	-4	no	247.229	248.106	EPSD;PhosphoSitePlus	TCGA;COSMIC;GDSC;CCLE	187.474	Up-regulation
Other_IKK_CHUK_ST	P35222	CTNNB1	O15111	CHUK	S45	T41I	41	Missense	distal	-4	no	247.229	246.162	EPSD;PhosphoSitePlus	TCGA;COSMIC	187.474	Down-regulation
Other_IKK_CHUK_ST	P35222	CTNNB1	O15111	CHUK	S45	S45Y	45	Missense	central	0	yes	247.229	0.000	EPSD;PhosphoSitePlus	TCGA;COSMIC	187.474	Loss
Other_IKK_CHUK_ST	P35222	CTNNB1	O15111	CHUK	S45	T41N	41	Missense	distal	-4	no	247.229	267.710	EPSD;PhosphoSitePlus	TCGA;COSMIC	187.474	Up-regulation
Other_IKK_CHUK_ST	P35222	CTNNB1	O15111	CHUK	S45	S45C	45	Missense	central	0	yes	247.229	0.000	EPSD;PhosphoSitePlus	TCGA;COSMIC;GDSC;CCLE	187.474	Loss
Other_IKK_CHUK_ST	P35222	CTNNB1	O15111	CHUK	S47	S45F	45	Missense	proximal	-2	no	176.444	188.914	EPSD	TCGA;COSMIC;GDSC;CCLE	187.474	Gain
Other_IKK_CHUK_ST	P35222	CTNNB1	O15111	CHUK	S179	R185G	185	Missense	distal	6	no	210.016	204.063	EPSD	TCGA;COSMIC	187.474	Down-regulation
Other_IKK_CHUK_ST	P35222	CTNNB1	O15111	CHUK	S605	P606L	606	Missense	proximal	1	no	174.986	189.059	EPSD	TCGA;COSMIC	187.474	Gain
Other_IKK_CHUK_ST	P35222	CTNNB1	O15111	CHUK	S715	R717H	717	Missense	proximal	2	no	200.492	202.340	EPSD	TCGA;COSMIC	187.474	Up-regulation
Other_IKK_CHUK_ST	P35222	CTNNB1	O15111	CHUK	S715	P714R	714	Missense	proximal	-1	no	200.492	199.934	EPSD	TCGA;COSMIC	187.474	Down-regulation
Other_IKK_CHUK_ST	P35222	CTNNB1	O15111	CHUK	S715	P714L	714	Missense	proximal	-1	no	200.492	202.484	EPSD	TCGA;COSMIC	187.474	Up-regulation
Other_IKK_CHUK_ST	P35222	CTNNB1	O15111	CHUK	S718	R717H	717	Missense	proximal	-1	no	216.341	217.587	EPSD	TCGA;COSMIC	187.474	Up-regulation
Other_IKK_CHUK_ST	P35222	CTNNB1	O15111	CHUK	S718	P714R	714	Missense	distal	-4	no	216.341	204.708	EPSD	TCGA;COSMIC	187.474	Down-regulation
Other_IKK_CHUK_ST	P35222	CTNNB1	O15111	CHUK	S718	P714L	714	Missense	distal	-4	no	216.341	188.108	EPSD	TCGA;COSMIC	187.474	Down-regulation
Other_IKK_CHUK_ST	Q8N3F0	MTURN	O15111	CHUK	S58	W57C	57	Missense	proximal	-1	no	240.714	241.543	PhosphoSitePlus	TCGA;COSMIC	187.474	Up-regulation
Other_IKK_CHUK_ST	Q8N3F0	MTURN	O15111	CHUK	S58	P65L	65	Missense	distal	7	no	240.714	235.185	PhosphoSitePlus	TCGA;COSMIC	187.474	Down-regulation
Other_IKK_CHUK_ST	Q92793	CREBBP	O15111	CHUK	S23	D29Y	29	Missense	distal	6	no	243.424	243.090	EPSD	TCGA;ICGC;COSMIC	187.474	Down-regulation
Other_IKK_CHUK_ST	Q92793	CREBBP	O15111	CHUK	S306	T312A	312	Missense	distal	6	no	206.435	211.154	EPSD	TCGA;ICGC;COSMIC	187.474	Up-regulation
Other_IKK_CHUK_ST	Q92793	CREBBP	O15111	CHUK	S306	Q301H	301	Missense	distal	-5	no	206.435	206.685	EPSD	TCGA;ICGC;COSMIC	187.474	Up-regulation
Other_IKK_CHUK_ST	Q92793	CREBBP	O15111	CHUK	S306	V304I	304	Missense	proximal	-2	no	206.435	207.142	EPSD	TCGA;ICGC;COSMIC	187.474	Up-regulation
Other_IKK_CHUK_ST	Q92793	CREBBP	O15111	CHUK	S306	P311S	311	Missense	distal	5	no	206.435	201.073	EPSD	TCGA;ICGC;COSMIC	187.474	Down-regulation
Other_IKK_CHUK_ST	Q92793	CREBBP	O15111	CHUK	S381	P383L	383	Missense	proximal	2	no	194.254	190.093	EPSD	TCGA;ICGC;COSMIC	187.474	Down-regulation
Other_IKK_CHUK_ST	Q92793	CREBBP	O15111	CHUK	S381	P383R	383	Missense	proximal	2	no	194.254	191.787	EPSD	TCGA;ICGC;COSMIC	187.474	Down-regulation
Other_IKK_CHUK_ST	Q92793	CREBBP	O15111	CHUK	S750	P746S	746	Missense	distal	-4	no	208.417	216.035	EPSD	TCGA;COSMIC	187.474	Up-regulation
Other_IKK_CHUK_ST	Q92793	CREBBP	O15111	CHUK	S750	V751I	751	Missense	proximal	1	no	208.417	207.077	EPSD	TCGA;COSMIC	187.474	Down-regulation
Other_IKK_CHUK_ST	Q92793	CREBBP	O15111	CHUK	S1030	E1024D	1024	Missense	distal	-6	no	192.517	189.292	EPSD	TCGA	187.474	Down-regulation
Other_IKK_CHUK_ST	Q92793	CREBBP	O15111	CHUK	S1030	E1023K	1023	Missense	distal	-7	no	192.517	194.310	EPSD	TCGA;COSMIC	187.474	Up-regulation
Other_IKK_CHUK_ST	Q92793	CREBBP	O15111	CHUK	S1030	G1028E	1028	Missense	proximal	-2	no	192.517	200.368	EPSD	TCGA	187.474	Up-regulation
Other_IKK_CHUK_ST	Q92793	CREBBP	O15111	CHUK	S1043	I1038M	1038	Missense	distal	-5	no	184.096	198.855	EPSD	TCGA;COSMIC	187.474	Gain
Other_IKK_CHUK_ST	Q92793	CREBBP	O15111	CHUK	S1382	F1389S	1389	Missense	distal	7	no	242.216	235.294	PhosphoSitePlus;EPSD	TCGA;COSMIC	187.474	Down-regulation
Other_IKK_CHUK_ST	Q92793	CREBBP	O15111	CHUK	S1382	M1385I	1385	Missense	distal	3	no	242.216	200.279	PhosphoSitePlus;EPSD	TCGA;COSMIC	187.474	Down-regulation
Other_IKK_CHUK_ST	Q92793	CREBBP	O15111	CHUK	S1386	F1389S	1389	Missense	distal	3	no	246.093	280.352	EPSD;PhosphoSitePlus	TCGA;COSMIC	187.474	Up-regulation
Other_IKK_CHUK_ST	Q92793	CREBBP	O15111	CHUK	S1386	M1385I	1385	Missense	proximal	-1	no	246.093	244.688	EPSD;PhosphoSitePlus	TCGA;COSMIC	187.474	Down-regulation
Other_IKK_CHUK_ST	Q92793	CREBBP	O15111	CHUK	S1386	R1392Q	1392	Missense	distal	6	no	246.093	242.997	EPSD;PhosphoSitePlus	TCGA;COSMIC	187.474	Down-regulation
Other_IKK_CHUK_ST	Q92793	CREBBP	O15111	CHUK	S1609	R1602C	1602	Missense	distal	-7	no	199.900	199.217	EPSD	TCGA;COSMIC	187.474	Down-regulation
Other_IKK_CHUK_ST	Q92793	CREBBP	O15111	CHUK	S1609	S1614P	1614	Missense	distal	5	no	199.900	205.263	EPSD	TCGA;COSMIC	187.474	Up-regulation
Other_IKK_CHUK_ST	Q92793	CREBBP	O15111	CHUK	S1609	S1614F	1614	Missense	distal	5	no	199.900	206.726	EPSD	TCGA;COSMIC	187.474	Up-regulation
Other_IKK_CHUK_ST	Q92793	CREBBP	O15111	CHUK	S1609	R1602L	1602	Missense	distal	-7	no	199.900	201.819	EPSD	TCGA;COSMIC	187.474	Up-regulation
Other_IKK_CHUK_ST	Q92793	CREBBP	O15111	CHUK	S1609	R1602H	1602	Missense	distal	-7	no	199.900	202.244	EPSD	TCGA;COSMIC	187.474	Up-regulation
Other_IKK_CHUK_ST	Q92793	CREBBP	O15111	CHUK	S1609	A1603T	1603	Missense	distal	-6	no	199.900	196.032	EPSD	TCGA;COSMIC	187.474	Down-regulation
Other_IKK_CHUK_ST	Q92793	CREBBP	O15111	CHUK	S2377	G2381V	2381	Missense	distal	4	no	192.886	200.002	EPSD	TCGA;COSMIC	187.474	Up-regulation
Other_IKK_CHUK_ST	Q92793	CREBBP	O15111	CHUK	S2377	G2381C	2381	Missense	distal	4	no	192.886	193.066	EPSD	TCGA;COSMIC	187.474	Up-regulation
Other_IKK_CHUK_ST	Q92793	CREBBP	O15111	CHUK	S2377	S2372L	2372	Missense	distal	-5	no	192.886	180.290	EPSD	TCGA;COSMIC	187.474	Loss
Other_IKK_CHUK_ST	Q92793	CREBBP	O15111	CHUK	S2377	H2384Q	2384	Missense	distal	7	no	192.886	183.488	EPSD	TCGA;COSMIC	187.474	Loss
Other_IKK_CHUK_ST	Q92793	CREBBP	O15111	CHUK	S2377	S2382F	2382	Missense	distal	5	no	192.886	199.712	EPSD	TCGA;COSMIC	187.474	Up-regulation
Other_IKK_CHUK_ST	Q92793	CREBBP	O15111	CHUK	S2377	P2371L	2371	Missense	distal	-6	no	192.886	184.977	EPSD	TCGA;COSMIC;GDSC;CCLE	187.474	Loss
Other_IKK_CHUK_ST	Q92793	CREBBP	O15111	CHUK	S2394	G2401W	2401	Missense	distal	7	no	192.098	190.897	EPSD	TCGA;COSMIC	187.474	Down-regulation
Other_IKK_CHUK_ST	Q92793	CREBBP	O15111	CHUK	S2422	D2429N	2429	Missense	distal	7	no	196.661	192.976	EPSD	TCGA;COSMIC	187.474	Down-regulation
Other_IKK_CHUK_ST	Q92793	CREBBP	O15111	CHUK	S2425	D2429N	2429	Missense	distal	4	no	228.994	231.751	EPSD	TCGA;COSMIC	187.474	Up-regulation
Other_IKK_CHUK_ST	Q92793	CREBBP	O15111	CHUK	T2430	D2429N	2429	Missense	proximal	-1	no	192.951	190.051	EPSD	TCGA;COSMIC	187.474	Down-regulation
Other_IKK_CHUK_ST	P42345	MTOR	O15111	CHUK	S27	K30N	30	Missense	distal	3	no	181.168	189.253	EPSD	TCGA;ICGC;COSMIC	187.474	Gain
Other_IKK_CHUK_ST	P42345	MTOR	O15111	CHUK	S31	K30N	30	Missense	proximal	-1	no	196.279	195.866	EPSD	TCGA;ICGC;COSMIC	187.474	Down-regulation
Other_IKK_CHUK_ST	P42345	MTOR	O15111	CHUK	S92	G85S	85	Missense	distal	-7	no	209.467	210.505	EPSD	TCGA;ICGC	187.474	Up-regulation
Other_IKK_CHUK_ST	P42345	MTOR	O15111	CHUK	S92	V96M	96	Missense	distal	4	no	209.467	206.574	EPSD	TCGA;ICGC	187.474	Down-regulation
Other_IKK_CHUK_ST	P42345	MTOR	O15111	CHUK	S831	Q838L	838	Missense	distal	7	no	189.489	191.688	EPSD	TCGA;ICGC;COSMIC	187.474	Up-regulation
Other_IKK_CHUK_ST	P42345	MTOR	O15111	CHUK	S831	A835S	835	Missense	distal	4	no	189.489	195.398	EPSD	TCGA;ICGC;COSMIC	187.474	Up-regulation
Other_IKK_CHUK_ST	P42345	MTOR	O15111	CHUK	S909	R910Q	910	Missense	proximal	1	no	187.512	196.531	EPSD	TCGA;ICGC;COSMIC	187.474	Up-regulation
Other_IKK_CHUK_ST	P42345	MTOR	O15111	CHUK	S909	V915F	915	Missense	distal	6	no	187.512	185.574	EPSD	TCGA;ICGC;COSMIC	187.474	Loss
Other_IKK_CHUK_ST	P42345	MTOR	O15111	CHUK	S1171	T1176M	1176	Missense	distal	5	no	191.963	195.619	EPSD	TCGA;ICGC;COSMIC	187.474	Up-regulation
Other_IKK_CHUK_ST	P42345	MTOR	O15111	CHUK	S1415	S1415F	1415	Missense	central	0	yes	232.439	0.000	PhosphoSitePlus	TCGA;ICGC	187.474	Loss
Other_IKK_CHUK_ST	P42345	MTOR	O15111	CHUK	S1982	S1980C	1980	Missense	proximal	-2	no	195.338	201.851	EPSD	TCGA;ICGC;COSMIC	187.474	Up-regulation
Other_IKK_CHUK_ST	P42345	MTOR	O15111	CHUK	S1982	T1977K	1977	Missense	distal	-5	no	195.338	193.419	EPSD	TCGA;ICGC;COSMIC	187.474	Down-regulation
Other_IKK_CHUK_ST	P42345	MTOR	O15111	CHUK	S1982	T1977R	1977	Missense	distal	-5	no	195.338	184.642	EPSD	TCGA;ICGC;COSMIC	187.474	Loss
Other_IKK_CHUK_ST	P42345	MTOR	O15111	CHUK	S1982	K1981E	1981	Missense	proximal	-1	no	195.338	194.789	EPSD	TCGA;ICGC;COSMIC;GDSC;CCLE	187.474	Down-regulation
Other_IKK_CHUK_ST	P42345	MTOR	O15111	CHUK	S1982	T1977I	1977	Missense	distal	-5	no	195.338	180.274	EPSD	TCGA;ICGC;COSMIC	187.474	Loss
Other_IKK_CHUK_ST	P42345	MTOR	O15111	CHUK	S2155	R2152C	2152	Missense	distal	-3	no	212.892	202.817	EPSD	TCGA;ICGC;COSMIC;GDSC;CCLE	187.474	Down-regulation
Other_IKK_CHUK_ST	P42345	MTOR	O15111	CHUK	S2155	S2155F	2155	Missense	central	0	yes	212.892	0.000	EPSD	TCGA;ICGC;COSMIC	187.474	Loss
Other_IKK_CHUK_ST	P42345	MTOR	O15111	CHUK	S2159	R2152C	2152	Missense	distal	-7	no	195.552	194.869	EPSD	TCGA;ICGC;COSMIC;GDSC;CCLE	187.474	Down-regulation
Other_IKK_CHUK_ST	P42345	MTOR	O15111	CHUK	S2159	S2155F	2155	Missense	distal	-4	no	195.552	167.883	EPSD	TCGA;ICGC;COSMIC	187.474	Loss
Other_IKK_CHUK_ST	P42345	MTOR	O15111	CHUK	T2173	P2169S	2169	Missense	distal	-4	no	187.539	195.157	EPSD	TCGA	187.474	Up-regulation
Other_IKK_CHUK_ST	P42345	MTOR	O15111	CHUK	T2173	L2172M	2172	Missense	proximal	-1	no	187.539	186.192	EPSD	TCGA;ICGC;COSMIC	187.474	Loss
Other_IKK_CHUK_ST	Q9Y618	NCOR2	O15111	CHUK	S132	D138Y	138	Missense	distal	6	no	213.348	213.014	EPSD	TCGA;ICGC;COSMIC	187.474	Down-regulation
Other_IKK_CHUK_ST	Q9Y618	NCOR2	O15111	CHUK	S132	G131V	131	Missense	proximal	-1	no	213.348	214.245	EPSD	TCGA;ICGC;COSMIC	187.474	Up-regulation
Other_IKK_CHUK_ST	Q9Y618	NCOR2	O15111	CHUK	S140	D138Y	138	Missense	proximal	-2	no	178.092	192.490	EPSD	TCGA;ICGC;COSMIC	187.474	Gain
Other_IKK_CHUK_ST	Q9Y618	NCOR2	O15111	CHUK	S592	Q599H	599	Missense	distal	7	no	196.406	205.804	EPSD	TCGA;COSMIC	187.474	Up-regulation
Other_IKK_CHUK_ST	Q9Y618	NCOR2	O15111	CHUK	S592	S592N	592	Missense	central	0	yes	196.406	0.000	EPSD	TCGA;COSMIC	187.474	Loss
Other_IKK_CHUK_ST	Q9Y618	NCOR2	O15111	CHUK	S1800	R1806W	1806	Missense	distal	6	no	184.440	189.314	EPSD	TCGA;COSMIC	187.474	Gain
Other_IKK_CHUK_ST	Q9Y618	NCOR2	O15111	CHUK	S2025	E2032Q	2032	Missense	distal	7	no	194.797	188.884	EPSD	TCGA;COSMIC	187.474	Down-regulation
Other_IKK_CHUK_ST	Q9Y618	NCOR2	O15111	CHUK	S2208	P2206T	2206	Missense	proximal	-2	no	210.292	238.334	EPSD	TCGA	187.474	Up-regulation
Other_IKK_CHUK_ST	Q9Y618	NCOR2	O15111	CHUK	S2315	G2318R	2318	Missense	distal	3	no	189.807	139.363	EPSD	TCGA	187.474	Loss
Other_IKK_CHUK_ST	Q04206	RELA	O15111	CHUK	T136	P140L	140	Missense	distal	4	no	192.720	193.511	EPSD	TCGA;ICGC;COSMIC	187.474	Up-regulation
Other_IKK_CHUK_ST	Q04206	RELA	O15111	CHUK	T136	R133H	133	Missense	distal	-3	no	192.720	180.030	EPSD	TCGA;ICGC;COSMIC	187.474	Loss
Other_IKK_CHUK_ST	Q04206	RELA	O15111	CHUK	T136	S131T	131	Missense	distal	-5	no	192.720	187.039	EPSD	TCGA;ICGC;COSMIC	187.474	Loss
Other_IKK_CHUK_ST	Q04206	RELA	O15111	CHUK	T136	N139S	139	Missense	distal	3	no	192.720	190.022	EPSD	TCGA;ICGC	187.474	Down-regulation
Other_IKK_CHUK_ST	Q04206	RELA	O15111	CHUK	S311	E307K	307	Missense	distal	-4	no	185.513	197.279	EPSD	TCGA;ICGC;COSMIC	187.474	Gain
Other_IKK_CHUK_ST	Q04206	RELA	O15111	CHUK	S338	A339T	339	Missense	proximal	1	no	202.094	207.770	EPSD	TCGA;ICGC;COSMIC;CCLE	187.474	Up-regulation
Other_IKK_CHUK_ST	Q04206	RELA	O15111	CHUK	S338	A332D	332	Missense	distal	-6	no	202.094	198.009	EPSD	TCGA;ICGC	187.474	Down-regulation
Other_IKK_CHUK_ST	Q04206	RELA	O15111	CHUK	S529	S529L	529	Missense	central	0	yes	209.821	0.000	EPSD	TCGA;ICGC;COSMIC;GDSC;CCLE	187.474	Loss
Other_IKK_CHUK_ST	Q04206	RELA	O15111	CHUK	S529	L528F	528	Missense	proximal	-1	no	209.821	207.701	EPSD	TCGA;ICGC;COSMIC	187.474	Down-regulation
Other_IKK_CHUK_ST	Q04206	RELA	O15111	CHUK	S536	S529L	529	Missense	distal	-7	no	262.961	259.989	PhosphoSitePlus	TCGA;ICGC;COSMIC;GDSC;CCLE	187.474	Down-regulation
Other_IKK_CHUK_ST	Q86VP1	TAX1BP1	O15111	CHUK	S3	T2A	2	Missense	proximal	-1	no	191.567	189.454	EPSD	TCGA;ICGC	187.474	Down-regulation
Other_IKK_CHUK_ST	Q86VP1	TAX1BP1	O15111	CHUK	S254	D257E	257	Missense	distal	3	no	237.788	192.021	EPSD	TCGA;ICGC;COSMIC	187.474	Down-regulation
Other_IKK_CHUK_ST	Q86VP1	TAX1BP1	O15111	CHUK	S254	T250N	250	Missense	distal	-4	no	237.788	258.269	EPSD	TCGA;ICGC;COSMIC	187.474	Up-regulation
Other_IKK_CHUK_ST	Q86VP1	TAX1BP1	O15111	CHUK	S499	D495Y	495	Missense	distal	-4	no	220.742	224.511	EPSD	TCGA;ICGC;GDSC;CCLE	187.474	Up-regulation
Other_IKK_CHUK_ST	Q86VP1	TAX1BP1	O15111	CHUK	S501	D495Y	495	Missense	distal	-6	no	192.712	195.775	EPSD	TCGA;ICGC;GDSC;CCLE	187.474	Up-regulation
Other_IKK_CHUK_ST	Q86VP1	TAX1BP1	O15111	CHUK	S593	A598T	598	Missense	distal	5	no	194.169	195.427	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	187.474	Up-regulation
Other_IKK_CHUK_ST	Q86VP1	TAX1BP1	O15111	CHUK	S593	Y587F	587	Missense	distal	-6	no	194.169	196.072	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	187.474	Up-regulation
Other_IKK_CHUK_ST	Q86VP1	TAX1BP1	O15111	CHUK	S593	Y587C	587	Missense	distal	-6	no	194.169	197.626	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	187.474	Up-regulation
Other_IKK_CHUK_ST	Q86VP1	TAX1BP1	O15111	CHUK	S666	S666C	666	Missense	central	0	yes	206.863	0.000	EPSD	TCGA;COSMIC	187.474	Loss
Other_IKK_CHUK_ST	Q86VP1	TAX1BP1	O15111	CHUK	S666	V673I	673	Missense	distal	7	no	206.863	196.018	EPSD	TCGA;COSMIC	187.474	Down-regulation
Other_IKK_CHUK_ST	Q86VP1	TAX1BP1	O15111	CHUK	S666	N672T	672	Missense	distal	6	no	206.863	198.111	EPSD	TCGA	187.474	Down-regulation
Other_IKK_CHUK_ST	Q86VP1	TAX1BP1	O15111	CHUK	S691	E692D	692	Missense	proximal	1	no	206.607	201.705	EPSD	TCGA	187.474	Down-regulation
Other_IKK_CHUK_ST	Q15717	ELAVL1	O15111	CHUK	S42	F40L	40	Missense	proximal	-2	no	193.084	192.155	EPSD	TCGA;ICGC	187.474	Down-regulation
Other_IKK_CHUK_ST	Q15717	ELAVL1	O15111	CHUK	S42	R37Q	37	Missense	distal	-5	no	193.084	197.719	EPSD	TCGA;ICGC;COSMIC	187.474	Up-regulation
Other_IKK_CHUK_ST	Q15717	ELAVL1	O15111	CHUK	S42	F40C	40	Missense	proximal	-2	no	193.084	187.127	EPSD	TCGA;ICGC	187.474	Loss
Other_IKK_CHUK_ST	Q15717	ELAVL1	O15111	CHUK	S242	P237S	237	Missense	distal	-5	no	195.762	204.416	EPSD	TCGA;ICGC;COSMIC	187.474	Up-regulation
Other_IKK_CHUK_ST	Q15717	ELAVL1	O15111	CHUK	S242	A240T	240	Missense	proximal	-2	no	195.762	173.343	EPSD	TCGA;ICGC;COSMIC;CCLE	187.474	Loss
Other_IKK_CHUK_ST	Q15717	ELAVL1	O15111	CHUK	S242	V236M	236	Missense	distal	-6	no	195.762	197.914	EPSD	TCGA;ICGC	187.474	Up-regulation
Other_IKK_CHUK_ST	Q15717	ELAVL1	O15111	CHUK	S304	N306S	306	Missense	proximal	2	no	229.646	226.689	PhosphoSitePlus	TCGA;ICGC;COSMIC	187.474	Down-regulation
Other_IKK_CHUK_ST	Q15717	ELAVL1	O15111	CHUK	S304	R309H	309	Missense	distal	5	no	229.646	231.442	PhosphoSitePlus	TCGA;ICGC;COSMIC	187.474	Up-regulation
Other_IKK_CHUK_ST	P24385	CCND1	O15111	CHUK	S197	P199S	199	Missense	proximal	2	no	194.072	190.244	EPSD	TCGA;ICGC;COSMIC	187.474	Down-regulation
Other_IKK_CHUK_ST	P24385	CCND1	O15111	CHUK	S197	D192Y	192	Missense	distal	-5	no	194.072	179.056	EPSD	TCGA;ICGC;COSMIC	187.474	Loss
Other_IKK_CHUK_ST	P24385	CCND1	O15111	CHUK	T286	P287R	287	Missense	proximal	1	no	205.012	193.335	PhosphoSitePlus	TCGA;ICGC;COSMIC;GDSC;CCLE	187.474	Down-regulation
Other_IKK_CHUK_ST	P24385	CCND1	O15111	CHUK	T286	P287T	287	Missense	proximal	1	no	205.012	203.230	PhosphoSitePlus	TCGA;ICGC;COSMIC;CCLE	187.474	Down-regulation
Other_IKK_CHUK_ST	P24385	CCND1	O15111	CHUK	T286	P287L	287	Missense	proximal	1	no	205.012	219.085	PhosphoSitePlus	TCGA;ICGC;COSMIC;GDSC;CCLE	187.474	Up-regulation
Other_IKK_CHUK_ST	P24385	CCND1	O15111	CHUK	T286	D282H	282	Missense	distal	-4	no	205.012	198.669	PhosphoSitePlus	TCGA;ICGC;COSMIC	187.474	Down-regulation
Other_IKK_CHUK_ST	P24385	CCND1	O15111	CHUK	T286	V290M	290	Missense	distal	4	no	205.012	202.119	PhosphoSitePlus	TCGA;ICGC	187.474	Down-regulation
Other_IKK_CHUK_ST	P24385	CCND1	O15111	CHUK	T286	P287H	287	Missense	proximal	1	no	205.012	192.422	PhosphoSitePlus	TCGA;ICGC;COSMIC	187.474	Down-regulation
Other_IKK_CHUK_ST	P24385	CCND1	O15111	CHUK	T286	T286R	286	Missense	central	0	yes	205.012	0.000	PhosphoSitePlus	TCGA;ICGC;COSMIC	187.474	Loss
Other_IKK_CHUK_ST	P24385	CCND1	O15111	CHUK	T286	V293G	293	Missense	distal	7	no	205.012	205.351	PhosphoSitePlus	TCGA;ICGC;COSMIC;CCLE	187.474	Up-regulation
Other_IKK_CHUK_ST	P24385	CCND1	O15111	CHUK	T286	T286I	286	Missense	central	0	yes	205.012	0.000	PhosphoSitePlus	TCGA;ICGC;COSMIC	187.474	Loss
Other_IKK_CHUK_ST	P24385	CCND1	O15111	CHUK	T286	P287S	287	Missense	proximal	1	no	205.012	199.611	PhosphoSitePlus	TCGA;ICGC;COSMIC	187.474	Down-regulation
Other_IKK_CHUK_ST	P24385	CCND1	O15111	CHUK	T286	V281E	281	Missense	distal	-5	no	205.012	203.859	PhosphoSitePlus	TCGA;ICGC;COSMIC	187.474	Down-regulation
Other_IKK_CHUK_ST	P24385	CCND1	O15111	CHUK	T286	T286A	286	Missense	central	0	yes	205.012	0.000	PhosphoSitePlus	TCGA;ICGC;COSMIC	187.474	Loss
Other_IKK_CHUK_ST	P20749	BCL3	O15111	CHUK	S448	P451S	451	Missense	distal	3	no	198.077	196.501	EPSD	TCGA;ICGC;COSMIC	187.474	Down-regulation
Other_IKK_CHUK_ST	P20749	BCL3	O15111	CHUK	S448	S448F	448	Missense	central	0	yes	198.077	0.000	EPSD	TCGA;ICGC;COSMIC	187.474	Loss
Other_IKK_CHUK_ST	P20749	BCL3	O15111	CHUK	S448	R443Q	443	Missense	distal	-5	no	198.077	202.711	EPSD	TCGA;ICGC;COSMIC	187.474	Up-regulation
Other_IKK_CHUK_ST	P20749	BCL3	O15111	CHUK	S454	P451S	451	Missense	distal	-3	no	206.791	192.923	PhosphoSitePlus	TCGA;ICGC;COSMIC	187.474	Down-regulation
Other_IKK_CHUK_ST	P20749	BCL3	O15111	CHUK	S454	S448F	448	Missense	distal	-6	no	206.791	210.803	PhosphoSitePlus	TCGA;ICGC;COSMIC	187.474	Up-regulation
Other_IKK_CHUK_ST	O43524	FOXO3	O15111	CHUK	S75	D68Y	68	Missense	distal	-7	no	199.097	195.952	EPSD	TCGA;ICGC;COSMIC	187.474	Down-regulation
Other_IKK_CHUK_ST	O43524	FOXO3	O15111	CHUK	S161	N159H	159	Missense	proximal	-2	no	192.266	204.056	EPSD	TCGA	187.474	Up-regulation
Other_IKK_CHUK_ST	O43524	FOXO3	O15111	CHUK	S161	L165P	165	Missense	distal	4	no	192.266	191.475	EPSD	TCGA;ICGC;COSMIC	187.474	Down-regulation
Other_IKK_CHUK_ST	O43524	FOXO3	O15111	CHUK	S202	S209F	209	Missense	distal	7	no	209.165	216.088	EPSD	TCGA;ICGC	187.474	Up-regulation
Other_IKK_CHUK_ST	O43524	FOXO3	O15111	CHUK	S202	G205S	205	Missense	distal	3	no	209.165	197.246	EPSD	TCGA;ICGC;COSMIC	187.474	Down-regulation
Other_IKK_CHUK_ST	O43524	FOXO3	O15111	CHUK	S202	S209Y	209	Missense	distal	7	no	209.165	213.894	EPSD	TCGA;ICGC;COSMIC	187.474	Up-regulation
Other_IKK_CHUK_ST	O43524	FOXO3	O15111	CHUK	S209	G205S	205	Missense	distal	-4	no	185.204	195.769	EPSD	TCGA;ICGC;COSMIC	187.474	Gain
Other_IKK_CHUK_ST	O43524	FOXO3	O15111	CHUK	S253	R248Q	248	Missense	distal	-5	no	196.328	200.963	EPSD	TCGA;ICGC;COSMIC	187.474	Up-regulation
Other_IKK_CHUK_ST	O43524	FOXO3	O15111	CHUK	S253	R250W	250	Missense	distal	-3	no	196.328	191.382	EPSD	TCGA;ICGC;COSMIC	187.474	Down-regulation
Other_IKK_CHUK_ST	O43524	FOXO3	O15111	CHUK	S253	R250Q	250	Missense	distal	-3	no	196.328	170.397	EPSD	TCGA;ICGC;COSMIC	187.474	Loss
Other_IKK_CHUK_ST	O43524	FOXO3	O15111	CHUK	S330	R323L	323	Missense	distal	-7	no	198.782	200.701	EPSD	TCGA;ICGC;COSMIC	187.474	Up-regulation
Other_IKK_CHUK_ST	O43524	FOXO3	O15111	CHUK	S330	V336D	336	Missense	distal	6	no	198.782	191.382	EPSD	TCGA;ICGC;COSMIC	187.474	Down-regulation
Other_IKK_CHUK_ST	O43524	FOXO3	O15111	CHUK	S330	E335K	335	Missense	distal	5	no	198.782	197.116	EPSD	TCGA;ICGC;COSMIC	187.474	Down-regulation
Other_IKK_CHUK_ST	O43524	FOXO3	O15111	CHUK	S330	M328I	328	Missense	proximal	-2	no	198.782	208.535	EPSD	TCGA;ICGC;COSMIC	187.474	Up-regulation
Other_IKK_CHUK_ST	O43524	FOXO3	O15111	CHUK	S644	N650S	650	Missense	distal	6	no	217.602	214.131	PhosphoSitePlus	TCGA;ICGC;COSMIC	187.474	Down-regulation
Other_IKK_CHUK_ST	O43524	FOXO3	O15111	CHUK	S666	A665S	665	Missense	proximal	-1	no	208.886	210.534	EPSD	TCGA;ICGC;COSMIC	187.474	Up-regulation
Other_IKK_CHUK_ST	O43524	FOXO3	O15111	CHUK	S666	S669R	669	Missense	distal	3	no	208.886	170.361	EPSD	TCGA;ICGC	187.474	Loss
Other_IKK_CHUK_ST	O43524	FOXO3	O15111	CHUK	S667	A665S	665	Missense	proximal	-2	no	191.044	165.389	EPSD	TCGA;ICGC;COSMIC	187.474	Loss
Other_IKK_CHUK_ST	O43524	FOXO3	O15111	CHUK	S667	S669R	669	Missense	proximal	2	no	191.044	192.406	EPSD	TCGA;ICGC	187.474	Up-regulation
Other_IKK_CHUK_ST	O43524	FOXO3	O15111	CHUK	S669	A665S	665	Missense	distal	-4	no	222.725	239.219	EPSD	TCGA;ICGC;COSMIC	187.474	Up-regulation
Other_IKK_CHUK_ST	O43524	FOXO3	O15111	CHUK	S669	S669R	669	Missense	central	0	yes	222.725	0.000	EPSD	TCGA;ICGC	187.474	Loss
Other_IKK_CHUK_ST	Q04864	REL	O15111	CHUK	S386	E385K	385	Missense	proximal	-1	no	211.624	212.173	EPSD	TCGA;ICGC;COSMIC	187.474	Up-regulation
Other_IKK_CHUK_ST	Q04864	REL	O15111	CHUK	S386	Y387H	387	Missense	proximal	1	no	211.624	205.130	EPSD	TCGA;ICGC;COSMIC	187.474	Down-regulation
Other_IKK_CHUK_ST	Q04864	REL	O15111	CHUK	S516	N521T	521	Missense	distal	5	no	221.815	223.199	EPSD	TCGA;ICGC	187.474	Up-regulation
Other_IKK_CHUK_ST	Q04864	REL	O15111	CHUK	S526	D532Y	532	Missense	distal	6	no	236.654	236.320	EPSD	TCGA;ICGC	187.474	Down-regulation
Other_IKK_CHUK_ST	Q04864	REL	O15111	CHUK	S526	N521T	521	Missense	distal	-5	no	236.654	240.812	EPSD	TCGA;ICGC	187.474	Up-regulation
Other_IKK_CHUK_ST	Q04864	REL	O15111	CHUK	S526	N525D	525	Missense	proximal	-1	no	236.654	239.554	EPSD	TCGA;ICGC;COSMIC	187.474	Up-regulation
Other_IKK_CHUK_ST	Q04864	REL	O15111	CHUK	S557	A561T	561	Missense	distal	4	no	248.915	251.602	PhosphoSitePlus	TCGA;ICGC;COSMIC	187.474	Up-regulation
Other_IKK_CHUK_ST	Q04864	REL	O15111	CHUK	S557	E563Q	563	Missense	distal	6	no	248.915	244.286	PhosphoSitePlus	TCGA;ICGC;COSMIC	187.474	Down-regulation
Other_IKK_CHUK_ST	Q04864	REL	O15111	CHUK	S557	E563D	563	Missense	distal	6	no	248.915	243.799	PhosphoSitePlus	TCGA;ICGC;COSMIC	187.474	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	O75469	NR1I2	P24941	CDK2	T133	K128N	128	Missense	distal	-5	no	8.159	8.175	EPSD;PhosphoSitePlus	TCGA;COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	O75469	NR1I2	P24941	CDK2	T135	K128N	128	Missense	distal	-7	no	9.815	9.781	EPSD;PhosphoSitePlus	TCGA;COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	O95295	SNAPIN	P24941	CDK2	S126	A122V	122	Missense	distal	-4	no	8.303	8.314	EPSD	TCGA;ICGC;COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	Q99638	RAD9A	P24941	CDK2	S277	D274N	274	Missense	distal	-3	no	17.034	16.989	EPSD	TCGA;ICGC;COSMIC;GDSC;CCLE	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	Q99638	RAD9A	P24941	CDK2	S336	E343Q	343	Missense	distal	7	no	14.003	13.804	EPSD	TCGA	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	Q99638	RAD9A	P24941	CDK2	S380	D386V	386	Missense	distal	6	no	13.307	13.321	EPSD	TCGA;ICGC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	Q8IZL8	PELP1	P24941	CDK2	S477	G484W	484	Missense	distal	7	no	13.646	13.865	PhosphoSitePlus;EPSD	TCGA;COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	Q8IZL8	PELP1	P24941	CDK2	S477	G480E	480	Missense	distal	3	no	13.646	14.369	PhosphoSitePlus;EPSD	TCGA;COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	Q8IZL8	PELP1	P24941	CDK2	S477	G480R	480	Missense	distal	3	no	13.646	15.466	PhosphoSitePlus;EPSD	TCGA;COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	Q8IZL8	PELP1	P24941	CDK2	S477	L473F	473	Missense	distal	-4	no	13.646	13.097	PhosphoSitePlus;EPSD	TCGA;COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	Q8IZL8	PELP1	P24941	CDK2	S477	P478S	478	Missense	proximal	1	no	13.646	2.381	PhosphoSitePlus;EPSD	TCGA;COSMIC	8.148	Loss
CMGC_CDK_CDK2_CDK2_ST	Q8IZL8	PELP1	P24941	CDK2	S481	G484W	484	Missense	distal	3	no	13.081	12.260	EPSD	TCGA;COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	Q8IZL8	PELP1	P24941	CDK2	S481	G480E	480	Missense	proximal	-1	no	13.081	12.817	EPSD	TCGA;COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	Q8IZL8	PELP1	P24941	CDK2	S481	G480R	480	Missense	proximal	-1	no	13.081	12.603	EPSD	TCGA;COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	Q8IZL8	PELP1	P24941	CDK2	S481	P478S	478	Missense	distal	-3	no	13.081	13.176	EPSD	TCGA;COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	Q8IZL8	PELP1	P24941	CDK2	S509	P507S	507	Missense	proximal	-2	no	9.356	8.705	EPSD	TCGA;COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	Q8IZL8	PELP1	P24941	CDK2	S509	K512N	512	Missense	distal	3	no	9.356	6.086	EPSD	TCGA;COSMIC	8.148	Loss
CMGC_CDK_CDK2_CDK2_ST	Q8IZL8	PELP1	P24941	CDK2	T647	P650L	650	Missense	distal	3	no	11.719	11.336	EPSD	TCGA;COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	Q8IZL8	PELP1	P24941	CDK2	T647	P653S	653	Missense	distal	6	no	11.719	11.721	EPSD	TCGA;COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	Q8IZL8	PELP1	P24941	CDK2	S658	P653S	653	Missense	distal	-5	no	16.159	16.115	EPSD	TCGA;COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	Q8IZL8	PELP1	P24941	CDK2	S658	P659L	659	Missense	proximal	1	no	16.159	6.338	EPSD	TCGA;COSMIC	8.148	Loss
CMGC_CDK_CDK2_CDK2_ST	Q8IZL8	PELP1	P24941	CDK2	T807	P813L	813	Missense	distal	6	no	10.151	10.152	EPSD	TCGA;COSMIC;CCLE	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	Q8IZL8	PELP1	P24941	CDK2	S991	P997S	997	Missense	distal	6	no	16.884	16.885	EPSD;PhosphoSitePlus	TCGA;COSMIC;CCLE	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	Q8IZL8	PELP1	P24941	CDK2	S991	P992L	992	Missense	proximal	1	no	16.884	7.063	EPSD;PhosphoSitePlus	TCGA;COSMIC	8.148	Loss
CMGC_CDK_CDK2_CDK2_ST	Q8IZL8	PELP1	P24941	CDK2	S991	E990V	990	Missense	proximal	-1	no	16.884	16.056	EPSD;PhosphoSitePlus	TCGA;COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	Q8IZL8	PELP1	P24941	CDK2	S1043	E1038D	1038	Missense	distal	-5	no	14.169	14.189	EPSD	TCGA;COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	Q8IZL8	PELP1	P24941	CDK2	S1073	E1070Q	1070	Missense	distal	-3	no	9.117	9.000	EPSD	TCGA;COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	Q8IZL8	PELP1	P24941	CDK2	S1073	Q1077H	1077	Missense	distal	4	no	9.117	8.818	EPSD	TCGA	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	Q8IZL8	PELP1	P24941	CDK2	T1082	Q1077H	1077	Missense	distal	-5	no	14.918	14.965	EPSD	TCGA	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	Q8IZL8	PELP1	P24941	CDK2	T1082	P1083L	1083	Missense	proximal	1	no	14.918	5.097	EPSD	TCGA;COSMIC	8.148	Loss
CMGC_CDK_CDK2_CDK2_ST	Q8IZL8	PELP1	P24941	CDK2	T1092	E1093D	1093	Missense	proximal	1	no	7.510	8.432	EPSD	TCGA;COSMIC	8.148	Gain
CMGC_CDK_CDK2_CDK2_ST	Q07820	MCL1	P24941	CDK2	S121	E123K	123	Missense	proximal	2	no	15.691	15.453	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	Q07820	MCL1	P24941	CDK2	T163	S162W	162	Missense	proximal	-1	no	13.606	15.202	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	Q07820	MCL1	P24941	CDK2	S202	T196R	196	Missense	distal	-6	no	8.475	8.477	EPSD	TCGA;ICGC;COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	Q08999	RBL2	P24941	CDK2	S8	P13L	13	Missense	distal	5	no	11.659	11.699	EPSD	TCGA;ICGC;COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	Q08999	RBL2	P24941	CDK2	S373	A371T	371	Missense	proximal	-2	no	8.209	8.160	EPSD	TCGA;COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	Q08999	RBL2	P24941	CDK2	S373	S366L	366	Missense	distal	-7	no	8.209	8.395	EPSD	TCGA;COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	Q08999	RBL2	P24941	CDK2	S413	S420F	420	Missense	distal	7	no	16.455	17.308	EPSD;PhosphoSitePlus	TCGA;COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	Q08999	RBL2	P24941	CDK2	T417	S420F	420	Missense	distal	3	no	14.105	14.029	EPSD;PhosphoSitePlus	TCGA;COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	Q08999	RBL2	P24941	CDK2	S603	E607K	607	Missense	distal	4	no	15.673	16.058	EPSD	TCGA;COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	Q08999	RBL2	P24941	CDK2	S603	P604S	604	Missense	proximal	1	no	15.673	4.407	EPSD	TCGA	8.148	Loss
CMGC_CDK_CDK2_CDK2_ST	Q08999	RBL2	P24941	CDK2	S603	P604A	604	Missense	proximal	1	no	15.673	1.270	EPSD	TCGA;COSMIC	8.148	Loss
CMGC_CDK_CDK2_CDK2_ST	Q08999	RBL2	P24941	CDK2	S662	P663A	663	Missense	proximal	1	no	15.758	1.355	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	8.148	Loss
CMGC_CDK_CDK2_CDK2_ST	Q08999	RBL2	P24941	CDK2	S688	D691N	691	Missense	distal	3	no	12.799	14.050	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	Q08999	RBL2	P24941	CDK2	T694	D691N	691	Missense	distal	-3	no	14.813	14.769	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	Q08999	RBL2	P24941	CDK2	T694	R697L	697	Missense	distal	3	no	14.813	12.711	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	Q08999	RBL2	P24941	CDK2	S966	V968F	968	Missense	proximal	2	no	12.735	12.863	EPSD	TCGA;ICGC;COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	Q08999	RBL2	P24941	CDK2	S966	M969T	969	Missense	distal	3	no	12.735	12.861	EPSD	TCGA;ICGC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	Q08999	RBL2	P24941	CDK2	T986	R989H	989	Missense	distal	3	no	15.821	15.125	EPSD	TCGA;ICGC;COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	Q08999	RBL2	P24941	CDK2	T986	P987H	987	Missense	proximal	1	no	15.821	9.063	EPSD	TCGA;ICGC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	Q08999	RBL2	P24941	CDK2	T986	G992V	992	Missense	distal	6	no	15.821	15.831	EPSD	TCGA;ICGC;COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	Q08999	RBL2	P24941	CDK2	S995	R989H	989	Missense	distal	-6	no	9.084	9.085	EPSD	TCGA;ICGC;COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	Q08999	RBL2	P24941	CDK2	S995	G992V	992	Missense	distal	-3	no	9.084	9.123	EPSD	TCGA;ICGC;COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	Q08999	RBL2	P24941	CDK2	S1035	P1032L	1032	Missense	distal	-3	no	12.670	12.599	EPSD	TCGA;ICGC;COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	Q08999	RBL2	P24941	CDK2	S1035	P1033T	1033	Missense	proximal	-2	no	12.670	12.637	EPSD	TCGA;ICGC;COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	Q08999	RBL2	P24941	CDK2	S1044	G1043S	1043	Missense	proximal	-1	no	15.930	14.410	EPSD;PhosphoSitePlus	TCGA	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	Q08999	RBL2	P24941	CDK2	S1059	P1055H	1055	Missense	distal	-4	no	16.065	15.461	EPSD	TCGA	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	Q08999	RBL2	P24941	CDK2	S1068	R1070Q	1070	Missense	proximal	2	no	14.605	14.505	EPSD;PhosphoSitePlus	TCGA;COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	Q08999	RBL2	P24941	CDK2	S1068	K1072T	1072	Missense	distal	4	no	14.605	14.486	EPSD;PhosphoSitePlus	TCGA;COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	Q08999	RBL2	P24941	CDK2	S1068	K1072N	1072	Missense	distal	4	no	14.605	14.183	EPSD;PhosphoSitePlus	TCGA	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	Q08999	RBL2	P24941	CDK2	S1080	K1083Q	1083	Missense	distal	3	no	17.587	14.854	EPSD;PhosphoSitePlus	TCGA	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	Q08999	RBL2	P24941	CDK2	T1097	R1102T	1102	Missense	distal	5	no	15.189	15.057	EPSD;PhosphoSitePlus	TCGA;COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	Q08999	RBL2	P24941	CDK2	T1097	R1093C	1093	Missense	distal	-4	no	15.189	14.681	EPSD;PhosphoSitePlus	TCGA;COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	Q08999	RBL2	P24941	CDK2	S1112	R1116T	1116	Missense	distal	4	no	17.304	17.707	EPSD;PhosphoSitePlus	TCGA;COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	Q08999	RBL2	P24941	CDK2	S1112	S1110N	1110	Missense	proximal	-2	no	17.304	16.612	EPSD;PhosphoSitePlus	TCGA;COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	Q08999	RBL2	P24941	CDK2	S1112	L1105I	1105	Missense	distal	-7	no	17.304	17.493	EPSD;PhosphoSitePlus	TCGA;COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	P10636	MAPT	P24941	CDK2	S46	T52I	52	Missense	distal	6	no	15.504	15.497	EPSD	TCGA;ICGC;COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	P10636	MAPT	P24941	CDK2	S46	P47S	47	Missense	proximal	1	no	15.504	4.238	EPSD	TCGA;ICGC;COSMIC	8.148	Loss
CMGC_CDK_CDK2_CDK2_ST	P10636	MAPT	P24941	CDK2	S46	P47L	47	Missense	proximal	1	no	15.504	5.683	EPSD	TCGA;ICGC;COSMIC	8.148	Loss
CMGC_CDK_CDK2_CDK2_ST	P10636	MAPT	P24941	CDK2	S46	G42C	42	Missense	distal	-4	no	15.504	15.071	EPSD	TCGA;ICGC;COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	P10636	MAPT	P24941	CDK2	T50	D54E	54	Missense	distal	4	no	13.521	13.603	EPSD	TCGA;ICGC;COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	P10636	MAPT	P24941	CDK2	T50	T52I	52	Missense	proximal	2	no	13.521	13.676	EPSD	TCGA;ICGC;COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	P10636	MAPT	P24941	CDK2	T50	P47S	47	Missense	distal	-3	no	13.521	13.616	EPSD	TCGA;ICGC;COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	P10636	MAPT	P24941	CDK2	T50	P47L	47	Missense	distal	-3	no	13.521	13.450	EPSD	TCGA;ICGC;COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	P10636	MAPT	P24941	CDK2	T50	G55R	55	Missense	distal	5	no	13.521	13.501	EPSD	TCGA;ICGC;COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	P10636	MAPT	P24941	CDK2	T69	A72V	72	Missense	distal	3	no	13.645	14.765	EPSD	TCGA;ICGC;COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	P10636	MAPT	P24941	CDK2	T69	A66S	66	Missense	distal	-3	no	13.645	13.799	EPSD	TCGA;ICGC;COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	P10636	MAPT	P24941	CDK2	T111	E117K	117	Missense	distal	6	no	13.764	13.775	EPSD	TCGA;ICGC;COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	P10636	MAPT	P24941	CDK2	T111	A118V	118	Missense	distal	7	no	13.764	13.637	EPSD	TCGA;ICGC;COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	P10636	MAPT	P24941	CDK2	T167	R168H	168	Missense	proximal	1	no	5.339	8.379	EPSD	TCGA;ICGC;COSMIC	8.148	Gain
CMGC_CDK_CDK2_CDK2_ST	P10636	MAPT	P24941	CDK2	T173	R168C	168	Missense	distal	-5	no	9.577	9.611	EPSD	TCGA;ICGC;COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	P10636	MAPT	P24941	CDK2	S228	S232Y	232	Missense	distal	4	no	9.983	10.169	EPSD	TCGA;ICGC;COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	P10636	MAPT	P24941	CDK2	S228	D223Y	223	Missense	distal	-5	no	9.983	9.950	EPSD	TCGA;ICGC;COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	P10636	MAPT	P24941	CDK2	S228	S227F	227	Missense	proximal	-1	no	9.983	11.240	EPSD	TCGA;ICGC;COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	P10636	MAPT	P24941	CDK2	S228	P234L	234	Missense	distal	6	no	9.983	9.985	EPSD	TCGA;ICGC;COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	P10636	MAPT	P24941	CDK2	S232	S232Y	232	Missense	central	0	yes	15.341	0.000	EPSD	TCGA;ICGC;COSMIC	8.148	Loss
CMGC_CDK_CDK2_CDK2_ST	P10636	MAPT	P24941	CDK2	S232	S227F	227	Missense	distal	-5	no	15.341	15.458	EPSD	TCGA;ICGC;COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	P10636	MAPT	P24941	CDK2	S232	P234L	234	Missense	proximal	2	no	15.341	15.235	EPSD	TCGA;ICGC;COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	P10636	MAPT	P24941	CDK2	S238	A240T	240	Missense	proximal	2	no	14.454	14.252	EPSD	TCGA;ICGC;COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	P10636	MAPT	P24941	CDK2	S238	P234L	234	Missense	distal	-4	no	14.454	14.395	EPSD	TCGA;ICGC;COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	P10636	MAPT	P24941	CDK2	S238	R244Q	244	Missense	distal	6	no	14.454	14.476	EPSD	TCGA;ICGC;COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	P10636	MAPT	P24941	CDK2	S388	G387R	387	Missense	proximal	-1	no	10.322	9.844	EPSD	TCGA;COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	P10636	MAPT	P24941	CDK2	S411	P415L	415	Missense	distal	4	no	12.787	12.899	EPSD	TCGA;ICGC;COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	P10636	MAPT	P24941	CDK2	T416	P415L	415	Missense	proximal	-1	no	13.499	13.319	EPSD	TCGA;ICGC;COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	P10636	MAPT	P24941	CDK2	S428	A430S	430	Missense	proximal	2	no	13.464	13.506	EPSD	TCGA;ICGC;COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	P10636	MAPT	P24941	CDK2	S428	V431L	431	Missense	distal	3	no	13.464	12.472	EPSD	TCGA;ICGC;COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	P10636	MAPT	P24941	CDK2	S428	A430V	430	Missense	proximal	2	no	13.464	13.562	EPSD	TCGA;ICGC;COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	P10636	MAPT	P24941	CDK2	S438	P436T	436	Missense	proximal	-2	no	13.556	13.523	EPSD	TCGA;ICGC;COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	P10636	MAPT	P24941	CDK2	S438	P436L	436	Missense	proximal	-2	no	13.556	13.332	EPSD	TCGA;ICGC;COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	P10636	MAPT	P24941	CDK2	S438	K440E	440	Missense	proximal	2	no	13.556	13.794	EPSD	TCGA;ICGC;COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	P10636	MAPT	P24941	CDK2	S438	S443F	443	Missense	distal	5	no	13.556	13.875	EPSD	TCGA;ICGC;COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	P10636	MAPT	P24941	CDK2	S438	V431L	431	Missense	distal	-7	no	13.556	13.542	EPSD	TCGA;ICGC;COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	P10636	MAPT	P24941	CDK2	S438	S444F	444	Missense	distal	6	no	13.556	13.537	EPSD	TCGA;ICGC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	P10636	MAPT	P24941	CDK2	T470	R472Q	472	Missense	proximal	2	no	10.897	10.797	EPSD	TCGA	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	P10636	MAPT	P24941	CDK2	T470	R472W	472	Missense	proximal	2	no	10.897	10.994	EPSD	TCGA;COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	P10636	MAPT	P24941	CDK2	T492	A485T	485	Missense	distal	-7	no	12.497	12.330	EPSD	TCGA;COSMIC;GDSC;CCLE	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	P10636	MAPT	P24941	CDK2	T492	P493Q	493	Missense	proximal	1	no	12.497	4.585	EPSD	TCGA;COSMIC	8.148	Loss
CMGC_CDK_CDK2_CDK2_ST	Q99728	BARD1	P24941	CDK2	S148	N141T	141	Missense	distal	-7	no	13.307	13.386	EPSD;PhosphoSitePlus	TCGA;ICGC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	Q99728	BARD1	P24941	CDK2	S148	S151N	151	Missense	distal	3	no	13.307	12.711	EPSD;PhosphoSitePlus	TCGA;COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	Q99728	BARD1	P24941	CDK2	S148	R150Q	150	Missense	proximal	2	no	13.307	13.208	EPSD;PhosphoSitePlus	TCGA;COSMIC;CCLE	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	Q99728	BARD1	P24941	CDK2	S184	S186N	186	Missense	proximal	2	no	12.220	12.083	EPSD	TCGA;COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	Q99728	BARD1	P24941	CDK2	S184	D190Y	190	Missense	distal	6	no	12.220	12.227	EPSD	TCGA;ICGC;COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	Q99728	BARD1	P24941	CDK2	S186	S186N	186	Missense	central	0	yes	9.780	0.000	EPSD	TCGA;COSMIC	8.148	Loss
CMGC_CDK_CDK2_CDK2_ST	Q99728	BARD1	P24941	CDK2	S186	S192F	192	Missense	distal	6	no	9.780	9.761	EPSD	TCGA	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	Q99728	BARD1	P24941	CDK2	S186	D190Y	190	Missense	distal	4	no	9.780	10.044	EPSD	TCGA;ICGC;COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	Q99728	BARD1	P24941	CDK2	S251	I254L	254	Missense	distal	3	no	15.213	15.498	PhosphoSitePlus;EPSD	TCGA;ICGC;COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	Q99728	BARD1	P24941	CDK2	S288	E284D	284	Missense	distal	-4	no	14.800	15.096	EPSD;PhosphoSitePlus	TCGA;ICGC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	Q99728	BARD1	P24941	CDK2	S288	P281S	281	Missense	distal	-7	no	14.800	14.620	EPSD;PhosphoSitePlus	TCGA;COSMIC;CCLE	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	Q99728	BARD1	P24941	CDK2	T299	K305T	305	Missense	distal	6	no	16.297	16.296	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	Q99728	BARD1	P24941	CDK2	T299	P300T	300	Missense	proximal	1	no	16.297	6.340	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	8.148	Loss
CMGC_CDK_CDK2_CDK2_ST	Q99728	BARD1	P24941	CDK2	T299	V298A	298	Missense	proximal	-1	no	16.297	16.070	EPSD;PhosphoSitePlus	TCGA;COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	Q99728	BARD1	P24941	CDK2	T299	E301Q	301	Missense	proximal	2	no	16.297	16.259	EPSD;PhosphoSitePlus	TCGA;COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	Q99728	BARD1	P24941	CDK2	S364	R370H	370	Missense	distal	6	no	12.963	12.974	EPSD	TCGA;ICGC;COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	Q99728	BARD1	P24941	CDK2	S391	I388V	388	Missense	distal	-3	no	13.256	13.379	EPSD	TCGA;ICGC;COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	Q99728	BARD1	P24941	CDK2	S391	T394A	394	Missense	distal	3	no	13.256	12.858	EPSD	TCGA;ICGC;COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	Q99728	BARD1	P24941	CDK2	S391	G393S	393	Missense	proximal	2	no	13.256	13.204	EPSD	TCGA;ICGC;COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	Q99728	BARD1	P24941	CDK2	T394	T394A	394	Missense	central	0	yes	13.132	0.000	EPSD	TCGA;ICGC;COSMIC	8.148	Loss
CMGC_CDK_CDK2_CDK2_ST	Q99728	BARD1	P24941	CDK2	T394	G393S	393	Missense	proximal	-1	no	13.132	11.613	EPSD	TCGA;ICGC;COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	Q99728	BARD1	P24941	CDK2	S410	A413T	413	Missense	distal	3	no	9.833	10.230	EPSD	TCGA;ICGC;COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	Q99728	BARD1	P24941	CDK2	S410	P411S	411	Missense	proximal	1	no	9.833	-1.433	EPSD	TCGA;ICGC;COSMIC	8.148	Loss
CMGC_CDK_CDK2_CDK2_ST	Q99728	BARD1	P24941	CDK2	S410	R406Q	406	Missense	distal	-4	no	9.833	9.857	EPSD	TCGA;ICGC;COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	Q99728	BARD1	P24941	CDK2	S496	K503T	503	Missense	distal	7	no	13.404	13.387	EPSD	TCGA;ICGC;COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	Q99728	BARD1	P24941	CDK2	S555	S551L	551	Missense	distal	-4	no	8.657	8.245	EPSD	TCGA;ICGC;COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	O43303	CCP110	P24941	CDK2	S19	L20P	20	Missense	proximal	1	no	2.969	12.790	EPSD	TCGA;ICGC;COSMIC	8.148	Gain
CMGC_CDK_CDK2_CDK2_ST	O43303	CCP110	P24941	CDK2	S45	H39Y	39	Missense	distal	-6	no	13.942	13.939	PhosphoSitePlus;EPSD	TCGA;ICGC;COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	O43303	CCP110	P24941	CDK2	S45	E51Q	51	Missense	distal	6	no	13.942	13.951	PhosphoSitePlus;EPSD	TCGA;ICGC;COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	O43303	CCP110	P24941	CDK2	S45	L44F	44	Missense	proximal	-1	no	13.942	14.908	PhosphoSitePlus;EPSD	TCGA;ICGC;COSMIC;CCLE	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	O43303	CCP110	P24941	CDK2	S170	F168C	168	Missense	proximal	-2	no	11.005	11.057	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	O43303	CCP110	P24941	CDK2	S366	M371V	371	Missense	distal	5	no	13.818	13.478	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	O43303	CCP110	P24941	CDK2	S366	S360L	360	Missense	distal	-6	no	13.818	13.819	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	O43303	CCP110	P24941	CDK2	S372	R377Q	377	Missense	distal	5	no	15.180	15.034	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC;GDSC;CCLE	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	O43303	CCP110	P24941	CDK2	S372	R379H	379	Missense	distal	7	no	15.180	14.822	EPSD;PhosphoSitePlus	TCGA;ICGC;GDSC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	O43303	CCP110	P24941	CDK2	S372	R379L	379	Missense	distal	7	no	15.180	14.721	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	O43303	CCP110	P24941	CDK2	S372	M371V	371	Missense	proximal	-1	no	15.180	14.087	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	O43303	CCP110	P24941	CDK2	S400	P393L	393	Missense	distal	-7	no	12.307	12.313	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	O43303	CCP110	P24941	CDK2	S400	K404Q	404	Missense	distal	4	no	12.307	11.967	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	O43303	CCP110	P24941	CDK2	S516	S510N	510	Missense	distal	-6	no	12.127	12.128	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	O43303	CCP110	P24941	CDK2	S551	L553F	553	Missense	proximal	2	no	12.140	12.498	EPSD	TCGA;ICGC;COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	O43303	CCP110	P24941	CDK2	T566	N573Y	573	Missense	distal	7	no	12.381	12.744	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	O43303	CCP110	P24941	CDK2	S606	E610V	610	Missense	distal	4	no	8.020	8.231	EPSD	TCGA;ICGC;COSMIC	8.148	Gain
CMGC_CDK_CDK2_CDK2_ST	O43303	CCP110	P24941	CDK2	S788	Q789E	789	Missense	proximal	1	no	8.763	7.509	EPSD	TCGA;ICGC;COSMIC	8.148	Loss
CMGC_CDK_CDK2_CDK2_ST	O43303	CCP110	P24941	CDK2	S906	R899K	899	Missense	distal	-7	no	14.700	14.309	EPSD	TCGA;ICGC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	Q15648	MED1	P24941	CDK2	T64	L69I	69	Missense	distal	5	no	10.470	10.522	EPSD	TCGA;ICGC;COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	Q15648	MED1	P24941	CDK2	T212	H218Y	218	Missense	distal	6	no	12.211	12.208	EPSD	TCGA;ICGC;COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	Q15648	MED1	P24941	CDK2	T212	G209V	209	Missense	distal	-3	no	12.211	12.251	EPSD	TCGA;ICGC;COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	Q15648	MED1	P24941	CDK2	S238	E244K	244	Missense	distal	6	no	15.247	15.258	EPSD	TCGA;ICGC;COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	Q15648	MED1	P24941	CDK2	S238	K235R	235	Missense	distal	-3	no	15.247	15.477	EPSD	TCGA;ICGC;COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	Q15648	MED1	P24941	CDK2	S434	E441K	441	Missense	distal	7	no	11.706	11.376	EPSD	TCGA;ICGC;COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	Q15648	MED1	P24941	CDK2	S434	S434F	434	Missense	central	0	yes	11.706	0.000	EPSD	TCGA;ICGC;COSMIC	8.148	Loss
CMGC_CDK_CDK2_CDK2_ST	Q15648	MED1	P24941	CDK2	S434	R427I	427	Missense	distal	-7	no	11.706	11.557	EPSD	TCGA;ICGC;COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	Q15648	MED1	P24941	CDK2	S434	P435L	435	Missense	proximal	1	no	11.706	1.886	EPSD	TCGA;ICGC;COSMIC	8.148	Loss
CMGC_CDK_CDK2_CDK2_ST	Q15648	MED1	P24941	CDK2	S434	G436W	436	Missense	proximal	2	no	11.706	11.845	EPSD	TCGA;ICGC;COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	Q15648	MED1	P24941	CDK2	T522	P523Q	523	Missense	proximal	1	no	14.849	6.938	EPSD	TCGA;ICGC;COSMIC	8.148	Loss
CMGC_CDK_CDK2_CDK2_ST	Q15648	MED1	P24941	CDK2	S558	P563S	563	Missense	distal	5	no	8.350	8.249	EPSD	TCGA;ICGC;COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	Q15648	MED1	P24941	CDK2	S558	N565I	565	Missense	distal	7	no	8.350	8.500	EPSD	TCGA;ICGC;COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	Q15648	MED1	P24941	CDK2	S558	N555S	555	Missense	distal	-3	no	8.350	8.424	EPSD	TCGA;ICGC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	Q15648	MED1	P24941	CDK2	S558	T561N	561	Missense	distal	3	no	8.350	7.901	EPSD	TCGA;ICGC;COSMIC	8.148	Loss
CMGC_CDK_CDK2_CDK2_ST	Q15648	MED1	P24941	CDK2	S558	G553S	553	Missense	distal	-5	no	8.350	8.226	EPSD	TCGA;ICGC;COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	Q15648	MED1	P24941	CDK2	S558	M557T	557	Missense	proximal	-1	no	8.350	7.037	EPSD	TCGA;ICGC;COSMIC	8.148	Loss
CMGC_CDK_CDK2_CDK2_ST	Q15648	MED1	P24941	CDK2	T562	P563S	563	Missense	proximal	1	no	13.317	2.051	EPSD	TCGA;ICGC;COSMIC	8.148	Loss
CMGC_CDK_CDK2_CDK2_ST	Q15648	MED1	P24941	CDK2	T562	N565I	565	Missense	distal	3	no	13.317	13.211	EPSD	TCGA;ICGC;COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	Q15648	MED1	P24941	CDK2	T562	N555S	555	Missense	distal	-7	no	13.317	13.218	EPSD	TCGA;ICGC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	Q15648	MED1	P24941	CDK2	T562	T561N	561	Missense	proximal	-1	no	13.317	13.506	EPSD	TCGA;ICGC;COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	Q15648	MED1	P24941	CDK2	T562	M557T	557	Missense	distal	-5	no	13.317	13.209	EPSD	TCGA;ICGC;COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	Q15648	MED1	P24941	CDK2	S621	T628M	628	Missense	distal	7	no	13.041	13.890	EPSD	TCGA;ICGC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	Q15648	MED1	P24941	CDK2	S621	P625A	625	Missense	distal	4	no	13.041	13.081	EPSD	TCGA;ICGC;COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	Q15648	MED1	P24941	CDK2	S621	H627D	627	Missense	distal	6	no	13.041	13.031	EPSD	TCGA;ICGC;COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	Q15648	MED1	P24941	CDK2	T623	T628M	628	Missense	distal	5	no	13.117	13.450	EPSD	TCGA;ICGC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	Q15648	MED1	P24941	CDK2	T623	P625A	625	Missense	proximal	2	no	13.117	13.141	EPSD	TCGA;ICGC;COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	Q15648	MED1	P24941	CDK2	T623	H627D	627	Missense	distal	4	no	13.117	13.289	EPSD	TCGA;ICGC;COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	Q15648	MED1	P24941	CDK2	T628	T628M	628	Missense	central	0	yes	13.507	0.000	EPSD	TCGA;ICGC	8.148	Loss
CMGC_CDK_CDK2_CDK2_ST	Q15648	MED1	P24941	CDK2	T628	P625A	625	Missense	distal	-3	no	13.507	13.448	EPSD	TCGA;ICGC;COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	Q15648	MED1	P24941	CDK2	T628	H627D	627	Missense	proximal	-1	no	13.507	14.143	EPSD	TCGA;ICGC;COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	Q15648	MED1	P24941	CDK2	S664	S671Y	671	Missense	distal	7	no	12.385	12.806	EPSD	TCGA;ICGC;COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	Q15648	MED1	P24941	CDK2	S664	S671F	671	Missense	distal	7	no	12.385	13.238	EPSD	TCGA;ICGC;COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	Q15648	MED1	P24941	CDK2	S675	S682L	682	Missense	distal	7	no	14.437	14.620	EPSD	TCGA;ICGC;COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	Q15648	MED1	P24941	CDK2	S675	S671Y	671	Missense	distal	-4	no	14.437	14.549	EPSD	TCGA;ICGC;COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	Q15648	MED1	P24941	CDK2	S675	R677H	677	Missense	proximal	2	no	14.437	14.356	EPSD	TCGA;ICGC;COSMIC;GDSC;CCLE	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	Q15648	MED1	P24941	CDK2	S675	R677C	677	Missense	proximal	2	no	14.437	14.425	EPSD	TCGA	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	Q15648	MED1	P24941	CDK2	S675	S682T	682	Missense	distal	7	no	14.437	14.286	EPSD	TCGA;ICGC;COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	Q15648	MED1	P24941	CDK2	S675	S671F	671	Missense	distal	-4	no	14.437	13.475	EPSD	TCGA;ICGC;COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	Q15648	MED1	P24941	CDK2	T805	S810Y	810	Missense	distal	5	no	17.602	17.777	EPSD	TCGA;ICGC;COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	Q15648	MED1	P24941	CDK2	S848	G847R	847	Missense	proximal	-1	no	16.825	16.347	EPSD	TCGA;ICGC;COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	Q15648	MED1	P24941	CDK2	S853	G847R	847	Missense	distal	-6	no	13.040	13.039	EPSD	TCGA;ICGC;COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	Q15648	MED1	P24941	CDK2	T1017	H1024Y	1024	Missense	distal	7	no	8.800	8.938	EPSD	TCGA;ICGC;COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	Q15648	MED1	P24941	CDK2	S1021	H1024Y	1024	Missense	distal	3	no	12.748	10.980	EPSD	TCGA;ICGC;COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	Q15648	MED1	P24941	CDK2	S1023	H1024Y	1024	Missense	proximal	1	no	8.771	0.030	EPSD	TCGA;ICGC;COSMIC	8.148	Loss
CMGC_CDK_CDK2_CDK2_ST	Q15648	MED1	P24941	CDK2	S1042	S1049C	1049	Missense	distal	7	no	12.277	13.070	EPSD	TCGA;ICGC;COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	Q15648	MED1	P24941	CDK2	T1051	S1049C	1049	Missense	proximal	-2	no	11.862	11.452	EPSD	TCGA;ICGC;COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	Q15648	MED1	P24941	CDK2	S1092	S1091F	1091	Missense	proximal	-1	no	7.311	8.568	EPSD	TCGA;ICGC;COSMIC	8.148	Gain
CMGC_CDK_CDK2_CDK2_ST	Q15648	MED1	P24941	CDK2	S1141	Q1135H	1135	Missense	distal	-6	no	9.201	9.202	EPSD	TCGA;ICGC;COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	Q15648	MED1	P24941	CDK2	S1141	S1143C	1143	Missense	proximal	2	no	9.201	9.281	EPSD	TCGA;ICGC;COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	Q15648	MED1	P24941	CDK2	S1141	G1139E	1139	Missense	proximal	-2	no	9.201	8.828	EPSD	TCGA;ICGC;COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	Q15648	MED1	P24941	CDK2	S1156	G1154D	1154	Missense	proximal	-2	no	12.453	13.061	EPSD	TCGA;ICGC;COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	Q15648	MED1	P24941	CDK2	S1156	S1149F	1149	Missense	distal	-7	no	12.453	13.005	EPSD	TCGA;ICGC;COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	Q15648	MED1	P24941	CDK2	S1156	S1156F	1156	Missense	central	0	yes	12.453	0.000	EPSD	TCGA;ICGC;COSMIC	8.148	Loss
CMGC_CDK_CDK2_CDK2_ST	Q15648	MED1	P24941	CDK2	S1192	H1195Y	1195	Missense	distal	3	no	13.648	11.880	EPSD	TCGA;ICGC;COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	Q15648	MED1	P24941	CDK2	S1207	P1208A	1208	Missense	proximal	1	no	17.974	3.571	PhosphoSitePlus;EPSD	TCGA;ICGC;COSMIC	8.148	Loss
CMGC_CDK_CDK2_CDK2_ST	Q15648	MED1	P24941	CDK2	T1215	P1208A	1208	Missense	distal	-7	no	16.403	16.567	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	Q15648	MED1	P24941	CDK2	T1215	S1218C	1218	Missense	distal	3	no	16.403	11.723	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	Q15648	MED1	P24941	CDK2	S1223	S1227L	1227	Missense	distal	4	no	14.926	15.024	EPSD	TCGA;ICGC;COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	Q15648	MED1	P24941	CDK2	S1223	S1218C	1218	Missense	distal	-5	no	14.926	15.051	EPSD	TCGA;ICGC;COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	Q15648	MED1	P24941	CDK2	S1229	S1227L	1227	Missense	proximal	-2	no	8.322	8.749	EPSD	TCGA;ICGC;COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	Q15648	MED1	P24941	CDK2	S1241	S1239L	1239	Missense	proximal	-2	no	7.786	8.213	EPSD	TCGA;ICGC;COSMIC	8.148	Gain
CMGC_CDK_CDK2_CDK2_ST	Q15648	MED1	P24941	CDK2	S1294	P1301L	1301	Missense	distal	7	no	16.915	16.945	EPSD	TCGA;ICGC;COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	Q15648	MED1	P24941	CDK2	S1379	S1379L	1379	Missense	central	0	yes	9.203	0.000	EPSD	TCGA;ICGC;COSMIC	8.148	Loss
CMGC_CDK_CDK2_CDK2_ST	Q15648	MED1	P24941	CDK2	S1401	P1402R	1402	Missense	proximal	1	no	12.838	3.040	EPSD	TCGA;ICGC;COSMIC	8.148	Loss
CMGC_CDK_CDK2_CDK2_ST	Q15648	MED1	P24941	CDK2	S1401	V1408M	1408	Missense	distal	7	no	12.838	13.125	EPSD	TCGA;ICGC;COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	Q15648	MED1	P24941	CDK2	S1433	S1439F	1439	Missense	distal	6	no	12.510	12.491	EPSD	TCGA;ICGC;COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	Q15648	MED1	P24941	CDK2	S1433	P1434L	1434	Missense	proximal	1	no	12.510	2.689	EPSD	TCGA;ICGC;COSMIC	8.148	Loss
CMGC_CDK_CDK2_CDK2_ST	Q15648	MED1	P24941	CDK2	S1433	I1436M	1436	Missense	distal	3	no	12.510	12.938	EPSD	TCGA;ICGC;COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	Q15648	MED1	P24941	CDK2	S1437	I1436M	1436	Missense	proximal	-1	no	7.366	8.433	EPSD	TCGA;ICGC;COSMIC	8.148	Gain
CMGC_CDK_CDK2_CDK2_ST	Q15648	MED1	P24941	CDK2	S1439	S1439F	1439	Missense	central	0	yes	9.100	0.000	EPSD	TCGA;ICGC;COSMIC	8.148	Loss
CMGC_CDK_CDK2_CDK2_ST	Q15648	MED1	P24941	CDK2	S1439	P1434L	1434	Missense	distal	-5	no	9.100	9.112	EPSD	TCGA;ICGC;COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	Q15648	MED1	P24941	CDK2	S1439	I1436M	1436	Missense	distal	-3	no	9.100	9.448	EPSD	TCGA;ICGC;COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	Q15648	MED1	P24941	CDK2	T1440	S1439F	1439	Missense	proximal	-1	no	13.335	14.591	EPSD	TCGA;ICGC;COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	Q15648	MED1	P24941	CDK2	T1440	I1436M	1436	Missense	distal	-4	no	13.335	12.737	EPSD	TCGA;ICGC;COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	Q15648	MED1	P24941	CDK2	S1447	P1448S	1448	Missense	proximal	1	no	13.552	2.286	EPSD	TCGA;ICGC;COSMIC	8.148	Loss
CMGC_CDK_CDK2_CDK2_ST	Q15648	MED1	P24941	CDK2	S1447	P1448A	1448	Missense	proximal	1	no	13.552	-0.852	EPSD	TCGA;ICGC;COSMIC	8.148	Loss
CMGC_CDK_CDK2_CDK2_ST	Q15648	MED1	P24941	CDK2	S1449	P1448S	1448	Missense	proximal	-1	no	9.152	8.681	EPSD	TCGA;ICGC;COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	Q15648	MED1	P24941	CDK2	S1449	P1448A	1448	Missense	proximal	-1	no	9.152	8.882	EPSD	TCGA;ICGC;COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	Q15648	MED1	P24941	CDK2	S1453	P1448S	1448	Missense	distal	-5	no	14.352	14.308	EPSD	TCGA;ICGC;COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	Q15648	MED1	P24941	CDK2	S1453	P1448A	1448	Missense	distal	-5	no	14.352	14.377	EPSD	TCGA;ICGC;COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	Q15648	MED1	P24941	CDK2	S1479	Q1477H	1477	Missense	proximal	-2	no	14.029	13.586	EPSD	TCGA;ICGC;COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	Q15648	MED1	P24941	CDK2	S1479	S1475F	1475	Missense	distal	-4	no	14.029	13.067	EPSD	TCGA	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	Q15648	MED1	P24941	CDK2	S1479	D1484V	1484	Missense	distal	5	no	14.029	13.823	EPSD	TCGA;ICGC;COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	Q15648	MED1	P24941	CDK2	S1479	D1484N	1484	Missense	distal	5	no	14.029	13.958	EPSD	TCGA;ICGC;COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	Q15648	MED1	P24941	CDK2	S1561	S1558L	1558	Missense	distal	-3	no	15.660	15.494	EPSD	TCGA;ICGC;COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	Q15648	MED1	P24941	CDK2	S1561	A1554S	1554	Missense	distal	-7	no	15.660	15.316	EPSD	TCGA;ICGC;COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	Q15648	MED1	P24941	CDK2	S1561	S1561I	1561	Missense	central	0	yes	15.660	0.000	EPSD	TCGA;ICGC	8.148	Loss
CMGC_CDK_CDK2_CDK2_ST	P62324	BTG1	P24941	CDK2	S159	T158M	158	Missense	proximal	-1	no	16.830	18.143	PhosphoSitePlus	TCGA;ICGC;COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	P62324	BTG1	P24941	CDK2	S159	P160L	160	Missense	proximal	1	no	16.830	7.009	PhosphoSitePlus	TCGA;ICGC;COSMIC	8.148	Loss
CMGC_CDK_CDK2_CDK2_ST	P62324	BTG1	P24941	CDK2	S159	P160T	160	Missense	proximal	1	no	16.830	6.873	PhosphoSitePlus	TCGA;ICGC;COSMIC	8.148	Loss
CMGC_CDK_CDK2_CDK2_ST	P62324	BTG1	P24941	CDK2	S159	T158P	158	Missense	proximal	-1	no	16.830	17.093	PhosphoSitePlus	TCGA;ICGC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	P19338	NCL	P24941	CDK2	S67	K71N	71	Missense	distal	4	no	16.712	16.290	EPSD	TCGA;ICGC;COSMIC;GDSC;CCLE	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	P19338	NCL	P24941	CDK2	T76	K71N	71	Missense	distal	-5	no	14.850	14.866	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC;GDSC;CCLE	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	P19338	NCL	P24941	CDK2	T76	P77L	77	Missense	proximal	1	no	14.850	5.029	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	8.148	Loss
CMGC_CDK_CDK2_CDK2_ST	P19338	NCL	P24941	CDK2	T84	A91T	91	Missense	distal	7	no	16.617	15.928	EPSD	TCGA;ICGC;COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	P19338	NCL	P24941	CDK2	T84	P77L	77	Missense	distal	-7	no	16.617	16.623	EPSD	TCGA;ICGC;COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	P19338	NCL	P24941	CDK2	T92	A91T	91	Missense	proximal	-1	no	15.307	15.314	EPSD	TCGA;ICGC;COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	P19338	NCL	P24941	CDK2	T121	G123A	123	Missense	proximal	2	no	15.552	15.459	PhosphoSitePlus;EPSD	TCGA;ICGC;COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	P19338	NCL	P24941	CDK2	S145	D151N	151	Missense	distal	6	no	9.344	9.363	EPSD	TCGA;ICGC;COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	P19338	NCL	P24941	CDK2	T214	T213S	213	Missense	proximal	-1	no	15.166	14.959	EPSD	TCGA;ICGC;COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	P19338	NCL	P24941	CDK2	T214	K219N	219	Missense	distal	5	no	15.166	15.324	EPSD	TCGA;ICGC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	P19338	NCL	P24941	CDK2	T464	Y463C	463	Missense	proximal	-1	no	8.694	8.128	EPSD	TCGA;ICGC;COSMIC	8.148	Loss
CMGC_CDK_CDK2_CDK2_ST	P19338	NCL	P24941	CDK2	T464	N470K	470	Missense	distal	6	no	8.694	8.699	EPSD	TCGA;ICGC;COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	P19338	NCL	P24941	CDK2	T464	Q469E	469	Missense	distal	5	no	8.694	8.813	EPSD	TCGA;ICGC;COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	P19338	NCL	P24941	CDK2	T464	R457Q	457	Missense	distal	-7	no	8.694	8.308	EPSD	TCGA;ICGC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	P19338	NCL	P24941	CDK2	T464	N470T	470	Missense	distal	6	no	8.694	8.698	EPSD	TCGA	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	P19338	NCL	P24941	CDK2	S482	W481C	481	Missense	proximal	-1	no	10.835	9.583	EPSD	TCGA;ICGC;COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	P19338	NCL	P24941	CDK2	T606	R604Q	604	Missense	proximal	-2	no	8.433	9.102	EPSD	TCGA;ICGC;COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	P13639	EEF2	P24941	CDK2	T34	L35P	35	Missense	proximal	1	no	1.243	11.064	EPSD	TCGA;ICGC	8.148	Gain
CMGC_CDK_CDK2_CDK2_ST	P13639	EEF2	P24941	CDK2	S279	S276L	276	Missense	distal	-3	no	13.431	13.265	EPSD	TCGA;ICGC;COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	P13639	EEF2	P24941	CDK2	S279	S274G	274	Missense	distal	-5	no	13.431	13.555	EPSD	TCGA;ICGC;COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	P13639	EEF2	P24941	CDK2	S279	E281K	281	Missense	proximal	2	no	13.431	13.194	EPSD	TCGA;ICGC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	P13639	EEF2	P24941	CDK2	S325	K330T	330	Missense	distal	5	no	9.540	9.568	EPSD	TCGA;ICGC;COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	P13639	EEF2	P24941	CDK2	S360	L358V	358	Missense	proximal	-2	no	13.618	13.192	EPSD	TCGA;ICGC;COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	P13639	EEF2	P24941	CDK2	S502	R506I	506	Missense	distal	4	no	16.016	16.108	EPSD	TCGA;ICGC;COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	P13639	EEF2	P24941	CDK2	S541	E539K	539	Missense	proximal	-2	no	9.287	9.888	EPSD	TCGA;ICGC;COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	P13639	EEF2	P24941	CDK2	S595	R601W	601	Missense	distal	6	no	16.187	16.180	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	P13639	EEF2	P24941	CDK2	S595	L590F	590	Missense	distal	-5	no	16.187	16.248	EPSD;PhosphoSitePlus	TCGA;ICGC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	P13639	EEF2	P24941	CDK2	S595	V589M	589	Missense	distal	-6	no	16.187	16.193	EPSD;PhosphoSitePlus	TCGA;ICGC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	Q9NYV6	RRN3	P24941	CDK2	S44	R51W	51	Missense	distal	7	no	15.360	15.759	PhosphoSitePlus	TCGA;ICGC;COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	Q9NYV6	RRN3	P24941	CDK2	S44	R47S	47	Missense	distal	3	no	15.360	13.675	PhosphoSitePlus	TCGA;ICGC;COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	Q9NYV6	RRN3	P24941	CDK2	T200	R195I	195	Missense	distal	-5	no	13.090	13.083	EPSD	TCGA;ICGC;COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	Q9NYV6	RRN3	P24941	CDK2	T623	V619M	619	Missense	distal	-4	no	14.114	13.414	EPSD	TCGA;COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	Q9NYV6	RRN3	P24941	CDK2	T629	F631L	631	Missense	proximal	2	no	10.139	9.781	EPSD	TCGA;COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	Q9NYV6	RRN3	P24941	CDK2	S633	S640F	640	Missense	distal	7	no	14.473	15.327	EPSD	TCGA;COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	Q9NYV6	RRN3	P24941	CDK2	S633	F631L	631	Missense	proximal	-2	no	14.473	15.362	EPSD	TCGA;COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	Q9NYV6	RRN3	P24941	CDK2	S640	S640F	640	Missense	central	0	yes	14.031	0.000	EPSD	TCGA;COSMIC	8.148	Loss
CMGC_CDK_CDK2_CDK2_ST	Q9NYV6	RRN3	P24941	CDK2	S640	P641S	641	Missense	proximal	1	no	14.031	2.765	EPSD	TCGA;COSMIC	8.148	Loss
CMGC_CDK_CDK2_CDK2_ST	Q9NYV6	RRN3	P24941	CDK2	S649	S649I	649	Missense	central	0	yes	10.961	0.000	EPSD	TCGA;COSMIC	8.148	Loss
CMGC_CDK_CDK2_CDK2_ST	Q9H211	CDT1	P24941	CDK2	S93	K100N	100	Missense	distal	7	no	13.057	13.250	EPSD	TCGA;ICGC;COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	Q9H211	CDT1	P24941	CDK2	S93	P94L	94	Missense	proximal	1	no	13.057	3.236	EPSD	TCGA;ICGC;COSMIC	8.148	Loss
CMGC_CDK_CDK2_CDK2_ST	Q9H211	CDT1	P24941	CDK2	T102	K100N	100	Missense	proximal	-2	no	11.500	10.671	EPSD	TCGA;ICGC;COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	Q9H211	CDT1	P24941	CDK2	T102	A104T	104	Missense	proximal	2	no	11.500	11.298	EPSD	TCGA;ICGC;COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	Q9H211	CDT1	P24941	CDK2	T102	A105T	105	Missense	distal	3	no	11.500	11.898	EPSD	TCGA;ICGC;COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	Q9H211	CDT1	P24941	CDK2	T152	E156D	156	Missense	distal	4	no	11.611	11.529	EPSD	TCGA;ICGC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	Q9H211	CDT1	P24941	CDK2	T152	E156K	156	Missense	distal	4	no	11.611	11.995	EPSD	TCGA;ICGC;COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	Q9H211	CDT1	P24941	CDK2	T152	G157D	157	Missense	distal	5	no	11.611	11.658	EPSD	TCGA;ICGC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	Q9H211	CDT1	P24941	CDK2	T213	P214H	214	Missense	proximal	1	no	13.571	6.813	EPSD	TCGA;ICGC;COSMIC	8.148	Loss
CMGC_CDK_CDK2_CDK2_ST	Q9H211	CDT1	P24941	CDK2	T213	T213M	213	Missense	central	0	yes	13.571	0.000	EPSD	TCGA;ICGC;COSMIC	8.148	Loss
CMGC_CDK_CDK2_CDK2_ST	Q9H211	CDT1	P24941	CDK2	T213	E212K	212	Missense	proximal	-1	no	13.571	12.686	EPSD	TCGA;ICGC;COSMIC;GDSC;CCLE	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	Q9H211	CDT1	P24941	CDK2	T213	N209S	209	Missense	distal	-4	no	13.571	13.787	EPSD	TCGA;ICGC;COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	Q9H211	CDT1	P24941	CDK2	S372	R366Q	366	Missense	distal	-6	no	14.541	14.542	EPSD	TCGA;ICGC;COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	Q9H211	CDT1	P24941	CDK2	S372	P373L	373	Missense	proximal	1	no	14.541	4.720	EPSD	TCGA;ICGC	8.148	Loss
CMGC_CDK_CDK2_CDK2_ST	Q9H211	CDT1	P24941	CDK2	S391	S386F	386	Missense	distal	-5	no	13.572	13.689	EPSD	TCGA;ICGC;COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	Q9H211	CDT1	P24941	CDK2	S391	R385H	385	Missense	distal	-6	no	13.572	13.574	EPSD	TCGA;ICGC;COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	Q9H211	CDT1	P24941	CDK2	T402	P404A	404	Missense	proximal	2	no	14.160	14.185	EPSD	TCGA;ICGC;COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	Q9H211	CDT1	P24941	CDK2	T402	A409T	409	Missense	distal	7	no	14.160	13.471	EPSD	TCGA;ICGC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	Q9H211	CDT1	P24941	CDK2	T406	P404A	404	Missense	proximal	-2	no	12.369	12.385	EPSD	TCGA;ICGC;COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	Q9H211	CDT1	P24941	CDK2	T406	A409T	409	Missense	distal	3	no	12.369	12.766	EPSD	TCGA;ICGC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	Q9H211	CDT1	P24941	CDK2	S411	P404A	404	Missense	distal	-7	no	12.954	13.118	EPSD	TCGA;ICGC;COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	Q9H211	CDT1	P24941	CDK2	S411	A409T	409	Missense	proximal	-2	no	12.954	12.904	EPSD	TCGA;ICGC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	O75179	ANKRD17	P24941	CDK2	S156	G161V	161	Missense	distal	5	no	8.165	8.005	EPSD	TCGA;COSMIC	8.148	Loss
CMGC_CDK_CDK2_CDK2_ST	O75179	ANKRD17	P24941	CDK2	T735	L734F	734	Missense	proximal	-1	no	11.447	12.412	EPSD	TCGA;ICGC;COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	O75179	ANKRD17	P24941	CDK2	T735	Q733E	733	Missense	proximal	-2	no	11.447	10.899	EPSD	TCGA;COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	O75179	ANKRD17	P24941	CDK2	T735	D740N	740	Missense	distal	5	no	11.447	11.376	EPSD	TCGA;COSMIC;GDSC;CCLE	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	O75179	ANKRD17	P24941	CDK2	S792	D794N	794	Missense	proximal	2	no	8.474	8.406	EPSD	TCGA;ICGC;COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	O75179	ANKRD17	P24941	CDK2	S792	L788M	788	Missense	distal	-4	no	8.474	7.784	EPSD	TCGA;ICGC;COSMIC	8.148	Loss
CMGC_CDK_CDK2_CDK2_ST	O75179	ANKRD17	P24941	CDK2	T1287	S1294C	1294	Missense	distal	7	no	13.356	14.149	EPSD	TCGA;COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	O75179	ANKRD17	P24941	CDK2	S1639	R1633C	1633	Missense	distal	-6	no	11.890	11.893	EPSD	TCGA;ICGC;COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	O75179	ANKRD17	P24941	CDK2	S1639	N1637S	1637	Missense	proximal	-2	no	11.890	12.582	EPSD	TCGA;COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	O75179	ANKRD17	P24941	CDK2	S1709	P1710A	1710	Missense	proximal	1	no	15.165	0.761	EPSD	TCGA;COSMIC	8.148	Loss
CMGC_CDK_CDK2_CDK2_ST	O75179	ANKRD17	P24941	CDK2	S1709	R1712C	1712	Missense	distal	3	no	15.165	8.801	EPSD	TCGA;COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	O75179	ANKRD17	P24941	CDK2	S1933	P1928H	1928	Missense	distal	-5	no	13.630	13.677	EPSD	TCGA;COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	O75179	ANKRD17	P24941	CDK2	S1933	A1937S	1937	Missense	distal	4	no	13.630	13.603	EPSD	TCGA	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	O75179	ANKRD17	P24941	CDK2	S1933	S1940L	1940	Missense	distal	7	no	13.630	13.812	EPSD	TCGA;COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	O75179	ANKRD17	P24941	CDK2	S1940	V1946M	1946	Missense	distal	6	no	11.413	11.396	EPSD	TCGA;COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	O75179	ANKRD17	P24941	CDK2	S1940	P1943H	1943	Missense	distal	3	no	11.413	12.435	EPSD	TCGA	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	O75179	ANKRD17	P24941	CDK2	S1940	A1937S	1937	Missense	distal	-3	no	11.413	11.567	EPSD	TCGA	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	O75179	ANKRD17	P24941	CDK2	S1940	S1940L	1940	Missense	central	0	yes	11.413	0.000	EPSD	TCGA;COSMIC	8.148	Loss
CMGC_CDK_CDK2_CDK2_ST	O75179	ANKRD17	P24941	CDK2	S1991	T1985A	1985	Missense	distal	-6	no	12.162	12.161	EPSD	TCGA;COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	O75179	ANKRD17	P24941	CDK2	S1991	V1994I	1994	Missense	distal	3	no	12.162	10.886	EPSD	TCGA;COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	O75179	ANKRD17	P24941	CDK2	S1991	R1995Q	1995	Missense	distal	4	no	12.162	12.343	EPSD	TCGA;COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	O75179	ANKRD17	P24941	CDK2	S2059	V2055A	2055	Missense	distal	-4	no	9.089	9.078	EPSD	TCGA	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	O75179	ANKRD17	P24941	CDK2	S2067	A2072V	2072	Missense	distal	5	no	13.957	13.914	EPSD	TCGA;COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	O75179	ANKRD17	P24941	CDK2	S2081	E2076K	2076	Missense	distal	-5	no	14.526	14.491	EPSD	TCGA;COSMIC;GDSC;CCLE	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	O75179	ANKRD17	P24941	CDK2	T2279	S2285P	2285	Missense	distal	6	no	10.431	10.430	EPSD	TCGA;COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	O75179	ANKRD17	P24941	CDK2	S2318	S2318G	2318	Missense	central	0	yes	10.816	0.000	EPSD	TCGA;COSMIC	8.148	Loss
CMGC_CDK_CDK2_CDK2_ST	O75179	ANKRD17	P24941	CDK2	S2373	S2373P	2373	Missense	central	0	yes	12.223	0.000	EPSD	TCGA;COSMIC	8.148	Loss
CMGC_CDK_CDK2_CDK2_ST	O75179	ANKRD17	P24941	CDK2	T2379	A2384T	2384	Missense	distal	5	no	11.366	11.331	EPSD	TCGA;COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	O75179	ANKRD17	P24941	CDK2	T2379	S2373P	2373	Missense	distal	-6	no	11.366	11.367	EPSD	TCGA;COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	O75179	ANKRD17	P24941	CDK2	S2395	S2388Y	2388	Missense	distal	-7	no	7.882	8.188	EPSD	TCGA;COSMIC	8.148	Gain
CMGC_CDK_CDK2_CDK2_ST	O75179	ANKRD17	P24941	CDK2	S2401	P2408L	2408	Missense	distal	7	no	15.616	15.646	PhosphoSitePlus;EPSD	TCGA;COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	O75179	ANKRD17	P24941	CDK2	S2418	P2424T	2424	Missense	distal	6	no	9.260	9.268	EPSD	TCGA	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	O75179	ANKRD17	P24941	CDK2	T2509	Q2516R	2516	Missense	distal	7	no	14.493	15.137	EPSD	TCGA;COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	O75179	ANKRD17	P24941	CDK2	T2509	R2502Q	2502	Missense	distal	-7	no	14.493	14.106	EPSD	TCGA;COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	O14757	CHEK1	P24941	CDK2	S286	G289V	289	Missense	distal	3	no	12.386	13.095	PhosphoSitePlus;EPSD	TCGA;ICGC;COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	O14757	CHEK1	P24941	CDK2	S286	G281D	281	Missense	distal	-5	no	12.386	12.364	PhosphoSitePlus;EPSD	TCGA;ICGC;COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	O14757	CHEK1	P24941	CDK2	S286	T279I	279	Missense	distal	-7	no	12.386	12.583	PhosphoSitePlus;EPSD	TCGA;ICGC;COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	O14757	CHEK1	P24941	CDK2	S286	S284L	284	Missense	proximal	-2	no	12.386	12.813	PhosphoSitePlus;EPSD	TCGA;ICGC;COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	O14757	CHEK1	P24941	CDK2	S286	S288R	288	Missense	proximal	2	no	12.386	12.478	PhosphoSitePlus;EPSD	TCGA;ICGC;COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	O14757	CHEK1	P24941	CDK2	S301	S296F	296	Missense	distal	-5	no	16.125	16.242	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	O14757	CHEK1	P24941	CDK2	S301	N297T	297	Missense	distal	-4	no	16.125	16.154	EPSD;PhosphoSitePlus	TCGA;ICGC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	O14757	CHEK1	P24941	CDK2	S331	G324C	324	Missense	distal	-7	no	13.309	13.256	EPSD	TCGA;ICGC;COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	O14757	CHEK1	P24941	CDK2	S331	D336N	336	Missense	distal	5	no	13.309	13.238	EPSD	TCGA;ICGC;COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	O14757	CHEK1	P24941	CDK2	S331	K337R	337	Missense	distal	6	no	13.309	13.285	EPSD	TCGA;ICGC;COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	Q5JTZ9	AARS2	P24941	CDK2	T330	L331H	331	Missense	proximal	1	no	6.940	10.002	EPSD	TCGA;ICGC;COSMIC	8.148	Gain
CMGC_CDK_CDK2_CDK2_ST	Q5JTZ9	AARS2	P24941	CDK2	T670	D665Y	665	Missense	distal	-5	no	14.019	13.986	EPSD	TCGA;ICGC;COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	Q5JTZ9	AARS2	P24941	CDK2	T673	R678W	678	Missense	distal	5	no	14.099	14.266	PhosphoSitePlus	TCGA;ICGC;COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	Q5JTZ9	AARS2	P24941	CDK2	S916	P919S	919	Missense	distal	3	no	12.922	12.956	EPSD	TCGA;COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	Q14202	ZMYM3	P24941	CDK2	S8	D5Y	5	Missense	distal	-3	no	10.302	10.352	EPSD	TCGA;ICGC;COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	Q14202	ZMYM3	P24941	CDK2	S51	S54L	54	Missense	distal	3	no	15.483	15.065	EPSD	TCGA;ICGC;COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	Q14202	ZMYM3	P24941	CDK2	S54	S54L	54	Missense	central	0	yes	8.853	0.000	EPSD	TCGA;ICGC;COSMIC	8.148	Loss
CMGC_CDK_CDK2_CDK2_ST	Q14202	ZMYM3	P24941	CDK2	T62	D69N	69	Missense	distal	7	no	15.713	14.933	EPSD	TCGA	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	Q14202	ZMYM3	P24941	CDK2	S91	P92L	92	Missense	proximal	1	no	16.805	6.984	EPSD	TCGA;ICGC;COSMIC	8.148	Loss
CMGC_CDK_CDK2_CDK2_ST	Q14202	ZMYM3	P24941	CDK2	S91	Y87S	87	Missense	distal	-4	no	16.805	16.694	EPSD	TCGA;ICGC;COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	Q14202	ZMYM3	P24941	CDK2	S91	P93A	93	Missense	proximal	2	no	16.805	16.830	EPSD	TCGA;ICGC;COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	Q14202	ZMYM3	P24941	CDK2	S91	E94D	94	Missense	distal	3	no	16.805	14.369	EPSD	TCGA;ICGC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	Q14202	ZMYM3	P24941	CDK2	S148	S148Y	148	Missense	central	0	yes	13.911	0.000	EPSD	TCGA;ICGC;COSMIC	8.148	Loss
CMGC_CDK_CDK2_CDK2_ST	Q14202	ZMYM3	P24941	CDK2	S154	E159K	159	Missense	distal	5	no	11.857	11.724	EPSD	TCGA;ICGC;COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	Q14202	ZMYM3	P24941	CDK2	S154	E161K	161	Missense	distal	7	no	11.857	11.527	EPSD	TCGA;ICGC;COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	Q14202	ZMYM3	P24941	CDK2	S154	S148Y	148	Missense	distal	-6	no	11.857	11.858	EPSD	TCGA;ICGC;COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	Q14202	ZMYM3	P24941	CDK2	S154	E160D	160	Missense	distal	6	no	11.857	11.845	EPSD	TCGA;ICGC;COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	Q14202	ZMYM3	P24941	CDK2	S172	S172F	172	Missense	central	0	yes	13.701	0.000	EPSD	TCGA;ICGC;COSMIC	8.148	Loss
CMGC_CDK_CDK2_CDK2_ST	Q14202	ZMYM3	P24941	CDK2	S172	P173S	173	Missense	proximal	1	no	13.701	2.435	EPSD	TCGA;ICGC	8.148	Loss
CMGC_CDK_CDK2_CDK2_ST	Q14202	ZMYM3	P24941	CDK2	S172	S172P	172	Missense	central	0	yes	13.701	0.000	EPSD	TCGA;ICGC;COSMIC	8.148	Loss
CMGC_CDK_CDK2_CDK2_ST	Q14202	ZMYM3	P24941	CDK2	S186	S186I	186	Missense	central	0	yes	13.368	0.000	EPSD	TCGA;ICGC	8.148	Loss
CMGC_CDK_CDK2_CDK2_ST	Q14202	ZMYM3	P24941	CDK2	S186	S192G	192	Missense	distal	6	no	13.368	13.355	EPSD	TCGA;ICGC;COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	Q14202	ZMYM3	P24941	CDK2	S186	P193H	193	Missense	distal	7	no	13.368	13.499	EPSD	TCGA;ICGC;COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	Q14202	ZMYM3	P24941	CDK2	S186	P187S	187	Missense	proximal	1	no	13.368	2.102	EPSD	TCGA;ICGC;COSMIC	8.148	Loss
CMGC_CDK_CDK2_CDK2_ST	Q14202	ZMYM3	P24941	CDK2	S192	S186I	186	Missense	distal	-6	no	13.959	13.962	EPSD	TCGA;ICGC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	Q14202	ZMYM3	P24941	CDK2	S192	S192G	192	Missense	central	0	yes	13.959	0.000	EPSD	TCGA;ICGC;COSMIC	8.148	Loss
CMGC_CDK_CDK2_CDK2_ST	Q14202	ZMYM3	P24941	CDK2	S192	P193H	193	Missense	proximal	1	no	13.959	7.200	EPSD	TCGA;ICGC;COSMIC	8.148	Loss
CMGC_CDK_CDK2_CDK2_ST	Q14202	ZMYM3	P24941	CDK2	S192	P187S	187	Missense	distal	-5	no	13.959	13.915	EPSD	TCGA;ICGC;COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	Q14202	ZMYM3	P24941	CDK2	S192	E197D	197	Missense	distal	5	no	13.959	14.054	EPSD	TCGA;ICGC;COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	Q14202	ZMYM3	P24941	CDK2	S263	D266H	266	Missense	distal	3	no	8.114	10.950	EPSD	TCGA;ICGC;COSMIC	8.148	Gain
CMGC_CDK_CDK2_CDK2_ST	Q14202	ZMYM3	P24941	CDK2	S287	R293C	293	Missense	distal	6	no	12.458	12.461	EPSD	TCGA;ICGC;COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	Q14202	ZMYM3	P24941	CDK2	S287	P284H	284	Missense	distal	-3	no	12.458	12.604	EPSD	TCGA;ICGC;COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	Q14202	ZMYM3	P24941	CDK2	S287	R293H	293	Missense	distal	6	no	12.458	12.469	EPSD	TCGA;ICGC;COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	Q14202	ZMYM3	P24941	CDK2	T316	T316A	316	Missense	central	0	yes	16.088	0.000	EPSD	TCGA;ICGC;COSMIC	8.148	Loss
CMGC_CDK_CDK2_CDK2_ST	Q14202	ZMYM3	P24941	CDK2	S464	G466V	466	Missense	proximal	2	no	15.660	15.665	EPSD	TCGA;ICGC;COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	Q14202	ZMYM3	P24941	CDK2	S464	L470P	470	Missense	distal	6	no	15.660	15.658	EPSD	TCGA;ICGC;COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	Q14202	ZMYM3	P24941	CDK2	S464	T462I	462	Missense	proximal	-2	no	15.660	15.539	EPSD	TCGA;ICGC;COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	Q14202	ZMYM3	P24941	CDK2	S464	E468A	468	Missense	distal	4	no	15.660	15.683	EPSD	TCGA;ICGC;COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	Q14202	ZMYM3	P24941	CDK2	S464	F471L	471	Missense	distal	7	no	15.660	14.988	EPSD	TCGA;ICGC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	Q14202	ZMYM3	P24941	CDK2	S582	G586V	586	Missense	distal	4	no	11.093	11.440	EPSD	TCGA;COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	Q14202	ZMYM3	P24941	CDK2	S582	G586D	586	Missense	distal	4	no	11.093	11.148	EPSD	TCGA	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	Q14202	ZMYM3	P24941	CDK2	S582	R580H	580	Missense	proximal	-2	no	11.093	11.319	EPSD	TCGA;COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	Q14202	ZMYM3	P24941	CDK2	S774	S774F	774	Missense	central	0	yes	12.518	0.000	EPSD	TCGA;COSMIC	8.148	Loss
CMGC_CDK_CDK2_CDK2_ST	Q14202	ZMYM3	P24941	CDK2	S774	P779S	779	Missense	distal	5	no	12.518	12.417	EPSD	TCGA	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	Q14202	ZMYM3	P24941	CDK2	T781	S774F	774	Missense	distal	-7	no	14.713	15.265	EPSD	TCGA;COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	Q14202	ZMYM3	P24941	CDK2	T781	P779S	779	Missense	proximal	-2	no	14.713	14.062	EPSD	TCGA	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	Q14202	ZMYM3	P24941	CDK2	S783	P779S	779	Missense	distal	-4	no	7.946	8.301	EPSD	TCGA	8.148	Gain
CMGC_CDK_CDK2_CDK2_ST	Q14202	ZMYM3	P24941	CDK2	T817	P813S	813	Missense	distal	-4	no	14.358	14.713	EPSD	TCGA;COSMIC;CCLE	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	Q14202	ZMYM3	P24941	CDK2	T826	K831N	831	Missense	distal	5	no	15.734	15.891	PhosphoSitePlus	TCGA;COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	Q14202	ZMYM3	P24941	CDK2	T826	R828C	828	Missense	proximal	2	no	15.734	15.721	PhosphoSitePlus	TCGA	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	Q14202	ZMYM3	P24941	CDK2	T826	R828H	828	Missense	proximal	2	no	15.734	15.653	PhosphoSitePlus	TCGA;COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	P15336	ATF2	P24941	CDK2	T69	P70S	70	Missense	proximal	1	no	14.316	3.050	EPSD	TCGA;COSMIC	8.148	Loss
CMGC_CDK_CDK2_CDK2_ST	P15336	ATF2	P24941	CDK2	T71	P70S	70	Missense	proximal	-1	no	14.670	14.199	EPSD	TCGA;COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	P15336	ATF2	P24941	CDK2	S90	E93Q	93	Missense	distal	3	no	15.244	14.597	EPSD	TCGA;COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	P15336	ATF2	P24941	CDK2	S90	G83D	83	Missense	distal	-7	no	15.244	15.161	EPSD	TCGA;COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	P15336	ATF2	P24941	CDK2	S112	T116A	116	Missense	distal	4	no	14.689	14.446	EPSD	TCGA;COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	P15336	ATF2	P24941	CDK2	S112	S112P	112	Missense	central	0	yes	14.689	0.000	EPSD	TCGA;COSMIC	8.148	Loss
CMGC_CDK_CDK2_CDK2_ST	P15336	ATF2	P24941	CDK2	T116	T116A	116	Missense	central	0	yes	12.048	0.000	PhosphoSitePlus	TCGA;COSMIC	8.148	Loss
CMGC_CDK_CDK2_CDK2_ST	P15336	ATF2	P24941	CDK2	T116	S112P	112	Missense	distal	-4	no	12.048	11.693	PhosphoSitePlus	TCGA;COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	P15336	ATF2	P24941	CDK2	S136	D135N	135	Missense	proximal	-1	no	12.538	11.709	EPSD	TCGA	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	P15336	ATF2	P24941	CDK2	S136	S136N	136	Missense	central	0	yes	12.538	0.000	EPSD	TCGA	8.148	Loss
CMGC_CDK_CDK2_CDK2_ST	P15336	ATF2	P24941	CDK2	S266	P267S	267	Missense	proximal	1	no	12.962	1.696	EPSD	TCGA;COSMIC	8.148	Loss
CMGC_CDK_CDK2_CDK2_ST	P15336	ATF2	P24941	CDK2	T325	P326S	326	Missense	proximal	1	no	13.346	2.080	EPSD	TCGA;COSMIC	8.148	Loss
CMGC_CDK_CDK2_CDK2_ST	P15336	ATF2	P24941	CDK2	T325	S321F	321	Missense	distal	-4	no	13.346	12.384	EPSD	TCGA;COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	P15336	ATF2	P24941	CDK2	S328	P326S	326	Missense	proximal	-2	no	12.868	12.217	EPSD	TCGA;COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	P15336	ATF2	P24941	CDK2	S328	P334A	334	Missense	distal	6	no	12.868	12.864	EPSD	TCGA;COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	P15336	ATF2	P24941	CDK2	S328	S321F	321	Missense	distal	-7	no	12.868	13.419	EPSD	TCGA;COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	P15336	ATF2	P24941	CDK2	T333	P326S	326	Missense	distal	-7	no	11.689	11.509	EPSD	TCGA;COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	P15336	ATF2	P24941	CDK2	T333	P334A	334	Missense	proximal	1	no	11.689	-2.714	EPSD	TCGA;COSMIC	8.148	Loss
CMGC_CDK_CDK2_CDK2_ST	P15336	ATF2	P24941	CDK2	T333	T339A	339	Missense	distal	6	no	11.689	11.677	EPSD	TCGA;COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	P15336	ATF2	P24941	CDK2	S446	Q453H	453	Missense	distal	7	no	12.249	12.535	EPSD	TCGA;COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	Q9UKM9	RALY	P24941	CDK2	S110	S106C	106	Missense	distal	-4	no	9.479	8.373	EPSD	TCGA;ICGC;COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	Q9UKM9	RALY	P24941	CDK2	S110	A107V	107	Missense	distal	-3	no	9.479	9.680	EPSD	TCGA;ICGC;COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	Q9UKM9	RALY	P24941	CDK2	S135	P136T	136	Missense	proximal	1	no	14.880	4.923	PhosphoSitePlus	TCGA;COSMIC	8.148	Loss
CMGC_CDK_CDK2_CDK2_ST	Q9UKM9	RALY	P24941	CDK2	S135	S135L	135	Missense	central	0	yes	14.880	0.000	PhosphoSitePlus	TCGA;COSMIC	8.148	Loss
CMGC_CDK_CDK2_CDK2_ST	Q9UKM9	RALY	P24941	CDK2	S135	L134V	134	Missense	proximal	-1	no	14.880	15.017	PhosphoSitePlus	TCGA	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	Q9UKM9	RALY	P24941	CDK2	S135	V137M	137	Missense	proximal	2	no	14.880	14.969	PhosphoSitePlus	TCGA;COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	Q9UKM9	RALY	P24941	CDK2	S135	R131W	131	Missense	distal	-4	no	14.880	14.123	PhosphoSitePlus	TCGA	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	Q9UKM9	RALY	P24941	CDK2	S135	A142V	142	Missense	distal	7	no	14.880	14.754	PhosphoSitePlus	TCGA	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	Q9UKM9	RALY	P24941	CDK2	S244	S239R	239	Missense	distal	-5	no	8.134	8.226	EPSD	TCGA;COSMIC	8.148	Gain
CMGC_CDK_CDK2_CDK2_ST	Q9UKM9	RALY	P24941	CDK2	T286	E281G	281	Missense	distal	-5	no	9.134	9.177	EPSD	TCGA;COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	P78317	RNF4	P24941	CDK2	T26	S30A	30	Missense	distal	4	no	13.011	13.038	PhosphoSitePlus;EPSD	TCGA	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	P78317	RNF4	P24941	CDK2	S101	R104K	104	Missense	distal	3	no	8.030	9.019	EPSD	TCGA;ICGC;COSMIC	8.148	Gain
CMGC_CDK_CDK2_CDK2_ST	P78317	RNF4	P24941	CDK2	T112	A116T	116	Missense	distal	4	no	14.391	14.634	EPSD;PhosphoSitePlus	TCGA;ICGC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	P38936	CDKN1A	P24941	CDK2	T57	G61V	61	Missense	distal	4	no	15.802	16.149	EPSD	TCGA;ICGC;COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	P38936	CDKN1A	P24941	CDK2	T57	E56K	56	Missense	proximal	-1	no	15.802	14.917	EPSD	TCGA;ICGC;COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	P38936	CDKN1A	P24941	CDK2	T57	P58L	58	Missense	proximal	1	no	15.802	5.982	EPSD	TCGA;ICGC;COSMIC	8.148	Loss
CMGC_CDK_CDK2_CDK2_ST	P38936	CDKN1A	P24941	CDK2	T80	R86W	86	Missense	distal	6	no	9.228	9.220	EPSD	TCGA;ICGC;COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	P38936	CDKN1A	P24941	CDK2	T80	D87N	87	Missense	distal	7	no	9.228	8.448	EPSD	TCGA;ICGC;COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	P38936	CDKN1A	P24941	CDK2	T80	P79S	79	Missense	proximal	-1	no	9.228	8.757	EPSD	TCGA;ICGC;COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	P38936	CDKN1A	P24941	CDK2	S98	R94W	94	Missense	distal	-4	no	12.155	11.397	EPSD	TCGA;ICGC;COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	P38936	CDKN1A	P24941	CDK2	S98	R93S	93	Missense	distal	-5	no	12.155	12.063	EPSD	TCGA;ICGC;COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	P38936	CDKN1A	P24941	CDK2	S98	R94P	94	Missense	distal	-4	no	12.155	12.397	EPSD	TCGA;ICGC;COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	P38936	CDKN1A	P24941	CDK2	S98	P95S	95	Missense	distal	-3	no	12.155	12.250	EPSD	TCGA;ICGC;COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	P38936	CDKN1A	P24941	CDK2	S130	D136H	136	Missense	distal	6	no	14.015	14.025	PhosphoSitePlus	TCGA;ICGC;COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	P38936	CDKN1A	P24941	CDK2	S130	G132C	132	Missense	proximal	2	no	14.015	14.043	PhosphoSitePlus	TCGA;ICGC;COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	P38936	CDKN1A	P24941	CDK2	S130	E128K	128	Missense	proximal	-2	no	14.015	14.616	PhosphoSitePlus	TCGA;ICGC;COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	P38936	CDKN1A	P24941	CDK2	S130	G135A	135	Missense	distal	5	no	14.015	13.898	PhosphoSitePlus	TCGA	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	P38936	CDKN1A	P24941	CDK2	S137	G135A	135	Missense	proximal	-2	no	7.729	8.488	EPSD	TCGA	8.148	Gain
CMGC_CDK_CDK2_CDK2_ST	Q8WYH8	ING5	P24941	CDK2	S57	S51C	51	Missense	distal	-6	no	12.411	12.417	EPSD	TCGA;ICGC;COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	Q8WYH8	ING5	P24941	CDK2	S57	T52M	52	Missense	distal	-5	no	12.411	12.519	EPSD	TCGA;ICGC;COSMIC;CCLE	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	Q8WYH8	ING5	P24941	CDK2	S57	S51F	51	Missense	distal	-6	no	12.411	12.416	EPSD	TCGA;ICGC;COSMIC;GDSC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	Q8WYH8	ING5	P24941	CDK2	S57	T55M	55	Missense	proximal	-2	no	12.411	10.360	EPSD	TCGA;COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	Q8WYH8	ING5	P24941	CDK2	S57	V62M	62	Missense	distal	5	no	12.411	12.752	EPSD	TCGA;ICGC;COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	Q8WYH8	ING5	P24941	CDK2	S118	M115I	115	Missense	distal	-3	no	8.876	8.527	EPSD	TCGA;ICGC;COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	Q8WYH8	ING5	P24941	CDK2	T152	T152A	152	Missense	central	0	yes	16.833	0.000	PhosphoSitePlus	TCGA;ICGC;COSMIC	8.148	Loss
CMGC_CDK_CDK2_CDK2_ST	Q99607	ELF4	P24941	CDK2	S151	E154K	154	Missense	distal	3	no	6.549	8.635	EPSD	TCGA;ICGC;COSMIC	8.148	Gain
CMGC_CDK_CDK2_CDK2_ST	Q99607	ELF4	P24941	CDK2	S188	D192G	192	Missense	distal	4	no	12.678	12.623	EPSD	TCGA;ICGC;COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	Q99607	ELF4	P24941	CDK2	S188	N184S	184	Missense	distal	-4	no	12.678	12.894	EPSD	TCGA;ICGC;COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	Q99607	ELF4	P24941	CDK2	S188	T181N	181	Missense	distal	-7	no	12.678	12.599	EPSD	TCGA;ICGC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	Q99607	ELF4	P24941	CDK2	S188	R185Q	185	Missense	distal	-3	no	12.678	12.548	EPSD	TCGA;ICGC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	Q99607	ELF4	P24941	CDK2	T191	D192G	192	Missense	proximal	1	no	7.870	8.801	EPSD	TCGA;ICGC;COSMIC	8.148	Gain
CMGC_CDK_CDK2_CDK2_ST	Q99607	ELF4	P24941	CDK2	T232	G237D	237	Missense	distal	5	no	8.109	8.156	EPSD	TCGA;ICGC;COSMIC	8.148	Gain
CMGC_CDK_CDK2_CDK2_ST	Q99607	ELF4	P24941	CDK2	S641	L637F	637	Missense	distal	-4	no	16.080	15.530	EPSD	TCGA;ICGC;COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	Q99607	ELF4	P24941	CDK2	T643	L637F	637	Missense	distal	-6	no	16.397	16.401	PhosphoSitePlus;EPSD	TCGA;ICGC;COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	Q99607	ELF4	P24941	CDK2	T643	F650C	650	Missense	distal	7	no	16.397	16.337	PhosphoSitePlus;EPSD	TCGA;ICGC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	Q99607	ELF4	P24941	CDK2	S648	P652H	652	Missense	distal	4	no	14.494	14.256	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	Q99607	ELF4	P24941	CDK2	S648	F650C	650	Missense	proximal	2	no	14.494	14.389	EPSD;PhosphoSitePlus	TCGA;ICGC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	Q99607	ELF4	P24941	CDK2	S648	S654F	654	Missense	distal	6	no	14.494	14.475	EPSD;PhosphoSitePlus	TCGA;ICGC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	P50570	DNM2	P24941	CDK2	S116	I120M	120	Missense	distal	4	no	12.816	12.423	EPSD	TCGA;ICGC;COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	P50570	DNM2	P24941	CDK2	S116	G114S	114	Missense	proximal	-2	no	12.816	12.907	EPSD	TCGA;ICGC;COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	P50570	DNM2	P24941	CDK2	S116	I120T	120	Missense	distal	4	no	12.816	13.127	EPSD	TCGA;ICGC;COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	P50570	DNM2	P24941	CDK2	S126	V129M	129	Missense	distal	3	no	16.601	15.753	EPSD	TCGA;ICGC;COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	P50570	DNM2	P24941	CDK2	S126	I120M	120	Missense	distal	-6	no	16.601	16.607	EPSD	TCGA;ICGC;COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	P50570	DNM2	P24941	CDK2	S126	I120T	120	Missense	distal	-6	no	16.601	16.599	EPSD	TCGA;ICGC;COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	P50570	DNM2	P24941	CDK2	T404	D406N	406	Missense	proximal	2	no	16.089	16.022	EPSD	TCGA;ICGC;COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	P50570	DNM2	P24941	CDK2	T404	A411S	411	Missense	distal	7	no	16.089	15.553	EPSD	TCGA;ICGC;COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	P50570	DNM2	P24941	CDK2	T404	T400M	400	Missense	distal	-4	no	16.089	15.175	EPSD	TCGA;ICGC;COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	P50570	DNM2	P24941	CDK2	T404	P405R	405	Missense	proximal	1	no	16.089	6.291	EPSD	TCGA	8.148	Loss
CMGC_CDK_CDK2_CDK2_ST	P50570	DNM2	P24941	CDK2	T404	R399W	399	Missense	distal	-5	no	16.089	16.177	EPSD	TCGA;ICGC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	Q05209	PTPN12	P24941	CDK2	S73	R74Q	74	Missense	proximal	1	no	6.915	8.802	EPSD	TCGA;ICGC;COSMIC	8.148	Gain
CMGC_CDK_CDK2_CDK2_ST	Q05209	PTPN12	P24941	CDK2	T81	R74Q	74	Missense	distal	-7	no	12.706	12.319	EPSD	TCGA;ICGC;COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	Q05209	PTPN12	P24941	CDK2	T81	D85N	85	Missense	distal	4	no	12.706	12.751	EPSD	TCGA;ICGC;COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	Q05209	PTPN12	P24941	CDK2	S332	D331N	331	Missense	proximal	-1	no	16.064	15.235	EPSD	TCGA;COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	Q05209	PTPN12	P24941	CDK2	T367	H360Y	360	Missense	distal	-7	no	13.910	13.913	EPSD	TCGA;COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	Q05209	PTPN12	P24941	CDK2	S468	K474T	474	Missense	distal	6	no	12.332	12.331	EPSD	TCGA	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	Q05209	PTPN12	P24941	CDK2	T509	N504D	504	Missense	distal	-5	no	14.883	14.921	EPSD	TCGA;COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	Q05209	PTPN12	P24941	CDK2	T519	R525C	525	Missense	distal	6	no	16.836	16.839	EPSD	TCGA;COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	Q05209	PTPN12	P24941	CDK2	T569	Q575K	575	Missense	distal	6	no	13.363	13.366	EPSD	TCGA;COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	Q05209	PTPN12	P24941	CDK2	S571	Q575K	575	Missense	distal	4	no	14.227	14.567	EPSD	TCGA;COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	Q05209	PTPN12	P24941	CDK2	T578	Q575K	575	Missense	distal	-3	no	15.168	15.069	EPSD	TCGA;COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	Q05209	PTPN12	P24941	CDK2	T578	D585N	585	Missense	distal	7	no	15.168	14.388	EPSD	TCGA;COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	Q05209	PTPN12	P24941	CDK2	S588	D585N	585	Missense	distal	-3	no	13.554	13.510	EPSD	TCGA;COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	Q05209	PTPN12	P24941	CDK2	T593	T598I	598	Missense	distal	5	no	11.681	11.800	EPSD	TCGA;COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	Q05209	PTPN12	P24941	CDK2	T618	S625L	625	Missense	distal	7	no	8.697	8.880	EPSD	TCGA;COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	Q05209	PTPN12	P24941	CDK2	S641	M648V	648	Missense	distal	7	no	9.087	8.800	EPSD	TCGA;COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	Q05209	PTPN12	P24941	CDK2	S641	T642A	642	Missense	proximal	1	no	9.087	4.641	EPSD	TCGA;COSMIC	8.148	Loss
CMGC_CDK_CDK2_CDK2_ST	Q05209	PTPN12	P24941	CDK2	S673	P678L	678	Missense	distal	5	no	11.748	11.787	EPSD	TCGA;COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	Q05209	PTPN12	P24941	CDK2	S673	R680I	680	Missense	distal	7	no	11.748	11.315	EPSD	TCGA;COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	Q05209	PTPN12	P24941	CDK2	T681	V686L	686	Missense	distal	5	no	10.377	10.450	EPSD	TCGA	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	Q05209	PTPN12	P24941	CDK2	T681	P678L	678	Missense	distal	-3	no	10.377	10.306	EPSD	TCGA;COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	Q05209	PTPN12	P24941	CDK2	T681	E683A	683	Missense	proximal	2	no	10.377	10.305	EPSD	TCGA;COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	Q05209	PTPN12	P24941	CDK2	T681	E683G	683	Missense	proximal	2	no	10.377	10.398	EPSD	TCGA	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	Q05209	PTPN12	P24941	CDK2	T681	R680I	680	Missense	proximal	-1	no	10.377	9.790	EPSD	TCGA;COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	Q05209	PTPN12	P24941	CDK2	T693	V686L	686	Missense	distal	-7	no	14.328	14.314	EPSD	TCGA	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	Q05209	PTPN12	P24941	CDK2	T693	S700T	700	Missense	distal	7	no	14.328	14.176	EPSD	TCGA;COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	Q05209	PTPN12	P24941	CDK2	S704	Q705H	705	Missense	proximal	1	no	8.016	9.169	EPSD	TCGA;COSMIC	8.148	Gain
CMGC_CDK_CDK2_CDK2_ST	Q05209	PTPN12	P24941	CDK2	S708	R707Q	707	Missense	proximal	-1	no	10.006	9.128	EPSD	TCGA;COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	Q05209	PTPN12	P24941	CDK2	S708	R707L	707	Missense	proximal	-1	no	10.006	9.256	EPSD	TCGA	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	Q05209	PTPN12	P24941	CDK2	S708	Q705H	705	Missense	distal	-3	no	10.006	10.094	EPSD	TCGA;COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	Q05209	PTPN12	P24941	CDK2	S708	K712R	712	Missense	distal	4	no	10.006	9.484	EPSD	TCGA	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	Q15788	NCOA1	P24941	CDK2	S22	S22L	22	Missense	central	0	yes	13.198	0.000	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	8.148	Loss
CMGC_CDK_CDK2_CDK2_ST	Q15788	NCOA1	P24941	CDK2	S325	R329K	329	Missense	distal	4	no	13.440	13.961	PhosphoSitePlus;EPSD	TCGA;ICGC;COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	Q15788	NCOA1	P24941	CDK2	S325	G321S	321	Missense	distal	-4	no	13.440	14.112	PhosphoSitePlus;EPSD	TCGA;ICGC;COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	Q15788	NCOA1	P24941	CDK2	S325	A323V	323	Missense	proximal	-2	no	13.440	12.774	PhosphoSitePlus;EPSD	TCGA;ICGC;COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	Q15788	NCOA1	P24941	CDK2	S325	G321D	321	Missense	distal	-4	no	13.440	14.285	PhosphoSitePlus;EPSD	TCGA;ICGC;COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	Q15788	NCOA1	P24941	CDK2	S372	H368Y	368	Missense	distal	-4	no	8.365	9.434	EPSD	TCGA;ICGC;COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	Q15788	NCOA1	P24941	CDK2	S372	S372C	372	Missense	central	0	yes	8.365	0.000	EPSD	TCGA;ICGC;COSMIC	8.148	Loss
CMGC_CDK_CDK2_CDK2_ST	Q15788	NCOA1	P24941	CDK2	S372	G370R	370	Missense	proximal	-2	no	8.365	7.871	EPSD	TCGA;ICGC;COSMIC	8.148	Loss
CMGC_CDK_CDK2_CDK2_ST	Q15788	NCOA1	P24941	CDK2	S372	D376E	376	Missense	distal	4	no	8.365	8.446	EPSD	TCGA;ICGC;COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	Q15788	NCOA1	P24941	CDK2	S395	P388L	388	Missense	distal	-7	no	15.481	15.486	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	Q15788	NCOA1	P24941	CDK2	S517	V519I	519	Missense	proximal	2	no	14.452	14.307	EPSD	TCGA;ICGC;COSMIC;GDSC;CCLE	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	Q15788	NCOA1	P24941	CDK2	S517	S513L	513	Missense	distal	-4	no	14.452	14.039	EPSD	TCGA;ICGC;COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	Q15788	NCOA1	P24941	CDK2	S517	P518S	518	Missense	proximal	1	no	14.452	3.186	EPSD	TCGA;ICGC;COSMIC	8.148	Loss
CMGC_CDK_CDK2_CDK2_ST	Q15788	NCOA1	P24941	CDK2	S517	S516R	516	Missense	proximal	-1	no	14.452	15.493	EPSD	TCGA;ICGC;COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	Q15788	NCOA1	P24941	CDK2	S517	S513A	513	Missense	distal	-4	no	14.452	14.039	EPSD	TCGA;ICGC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	Q15788	NCOA1	P24941	CDK2	S558	S551F	551	Missense	distal	-7	no	10.355	10.906	EPSD	TCGA;ICGC;COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	Q15788	NCOA1	P24941	CDK2	S569	R572T	572	Missense	distal	3	no	15.094	13.261	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	Q15788	NCOA1	P24941	CDK2	S569	S566A	566	Missense	distal	-3	no	15.094	14.940	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	Q15788	NCOA1	P24941	CDK2	S603	N600K	600	Missense	distal	-3	no	8.801	8.739	EPSD	TCGA;ICGC;COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	Q15788	NCOA1	P24941	CDK2	S698	S698R	698	Missense	central	0	yes	11.902	0.000	EPSD	TCGA;ICGC;COSMIC	8.148	Loss
CMGC_CDK_CDK2_CDK2_ST	Q15788	NCOA1	P24941	CDK2	T763	L766M	766	Missense	distal	3	no	12.212	12.355	EPSD	TCGA;ICGC;COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	Q15788	NCOA1	P24941	CDK2	T763	L768V	768	Missense	distal	5	no	12.212	12.139	EPSD	TCGA;ICGC;COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	Q15788	NCOA1	P24941	CDK2	T763	K758N	758	Missense	distal	-5	no	12.212	12.228	EPSD	TCGA;ICGC;COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	Q15788	NCOA1	P24941	CDK2	T763	L760V	760	Missense	distal	-3	no	12.212	12.425	EPSD	TCGA;ICGC;COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	Q15788	NCOA1	P24941	CDK2	T789	P794H	794	Missense	distal	5	no	14.593	14.670	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	Q15788	NCOA1	P24941	CDK2	T789	T792I	792	Missense	distal	3	no	14.593	14.039	EPSD;PhosphoSitePlus	TCGA;ICGC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	Q15788	NCOA1	P24941	CDK2	T979	I983M	983	Missense	distal	4	no	12.496	12.103	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	Q15788	NCOA1	P24941	CDK2	T979	P975T	975	Missense	distal	-4	no	12.496	12.662	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	Q15788	NCOA1	P24941	CDK2	S997	S999F	999	Missense	proximal	2	no	11.843	12.027	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	Q15788	NCOA1	P24941	CDK2	S999	S999F	999	Missense	central	0	yes	13.074	0.000	EPSD	TCGA;ICGC;COSMIC	8.148	Loss
CMGC_CDK_CDK2_CDK2_ST	Q15788	NCOA1	P24941	CDK2	S1006	S999F	999	Missense	distal	-7	no	13.477	14.028	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	Q15788	NCOA1	P24941	CDK2	T1026	P1022A	1022	Missense	distal	-4	no	13.395	13.337	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	Q15788	NCOA1	P24941	CDK2	T1026	S1033L	1033	Missense	distal	7	no	13.395	13.578	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	Q15788	NCOA1	P24941	CDK2	T1026	A1031D	1031	Missense	distal	5	no	13.395	13.559	EPSD;PhosphoSitePlus	TCGA;ICGC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	Q15788	NCOA1	P24941	CDK2	S1033	M1036I	1036	Missense	distal	3	no	15.362	14.934	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	Q15788	NCOA1	P24941	CDK2	S1033	P1034S	1034	Missense	proximal	1	no	15.362	4.096	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	8.148	Loss
CMGC_CDK_CDK2_CDK2_ST	Q15788	NCOA1	P24941	CDK2	S1033	S1033L	1033	Missense	central	0	yes	15.362	0.000	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	8.148	Loss
CMGC_CDK_CDK2_CDK2_ST	Q15788	NCOA1	P24941	CDK2	S1033	A1031D	1031	Missense	proximal	-2	no	15.362	15.211	EPSD;PhosphoSitePlus	TCGA;ICGC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	Q15788	NCOA1	P24941	CDK2	S1033	G1037D	1037	Missense	distal	4	no	15.362	15.417	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	Q15788	NCOA1	P24941	CDK2	S1250	A1243P	1243	Missense	distal	-7	no	10.963	10.798	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	Q15788	NCOA1	P24941	CDK2	S1250	P1251T	1251	Missense	proximal	1	no	10.963	1.005	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	8.148	Loss
CMGC_CDK_CDK2_CDK2_ST	Q15788	NCOA1	P24941	CDK2	T1271	S1275F	1275	Missense	distal	4	no	10.137	9.941	EPSD;PhosphoSitePlus	TCGA;GDSC;CCLE	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	Q15788	NCOA1	P24941	CDK2	T1271	Q1270K	1270	Missense	proximal	-1	no	10.137	10.344	EPSD;PhosphoSitePlus	TCGA	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	Q15788	NCOA1	P24941	CDK2	T1271	Q1270E	1270	Missense	proximal	-1	no	10.137	11.229	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	Q15788	NCOA1	P24941	CDK2	T1271	S1266Y	1266	Missense	distal	-5	no	10.137	10.206	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	Q15788	NCOA1	P24941	CDK2	S1279	S1275F	1275	Missense	distal	-4	no	15.314	14.352	EPSD;PhosphoSitePlus	TCGA;GDSC;CCLE	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	Q15788	NCOA1	P24941	CDK2	S1279	W1285L	1285	Missense	distal	6	no	15.314	15.339	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	Q15788	NCOA1	P24941	CDK2	T1426	Q1430H	1430	Missense	distal	4	no	12.764	12.465	EPSD;PhosphoSitePlus	TCGA	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	P23771	GATA3	P24941	CDK2	S110	T108S	108	Missense	proximal	-2	no	11.995	11.377	EPSD	TCGA;ICGC;COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	P23771	GATA3	P24941	CDK2	S110	T108N	108	Missense	proximal	-2	no	11.995	10.685	EPSD	TCGA;ICGC;COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	P23771	GATA3	P24941	CDK2	S110	A109T	109	Missense	proximal	-1	no	11.995	12.002	EPSD	TCGA;ICGC;COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	P23771	GATA3	P24941	CDK2	S110	L103M	103	Missense	distal	-7	no	11.995	12.490	EPSD	TCGA;ICGC;COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	P23771	GATA3	P24941	CDK2	S115	K119M	119	Missense	distal	4	no	12.062	11.239	EPSD	TCGA;ICGC;COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	P23771	GATA3	P24941	CDK2	S115	I122T	122	Missense	distal	7	no	12.062	11.701	EPSD	TCGA;ICGC;COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	P23771	GATA3	P24941	CDK2	S115	S118F	118	Missense	distal	3	no	12.062	11.986	EPSD	TCGA;ICGC;COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	P23771	GATA3	P24941	CDK2	S115	T108S	108	Missense	distal	-7	no	12.062	11.884	EPSD	TCGA;ICGC;COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	P23771	GATA3	P24941	CDK2	S115	T108N	108	Missense	distal	-7	no	12.062	11.983	EPSD	TCGA;ICGC;COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	P23771	GATA3	P24941	CDK2	S115	A109T	109	Missense	distal	-6	no	12.062	12.063	EPSD	TCGA;ICGC;COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	P23771	GATA3	P24941	CDK2	T156	P163L	163	Missense	distal	7	no	16.652	16.682	PhosphoSitePlus	TCGA;ICGC;COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	P23771	GATA3	P24941	CDK2	T156	V161I	161	Missense	distal	5	no	16.652	16.778	PhosphoSitePlus	TCGA;ICGC;COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	P23771	GATA3	P24941	CDK2	T156	P157T	157	Missense	proximal	1	no	16.652	6.695	PhosphoSitePlus	TCGA;ICGC;COSMIC	8.148	Loss
CMGC_CDK_CDK2_CDK2_ST	P23771	GATA3	P24941	CDK2	S162	P163L	163	Missense	proximal	1	no	12.164	2.343	EPSD	TCGA;ICGC;COSMIC	8.148	Loss
CMGC_CDK_CDK2_CDK2_ST	P23771	GATA3	P24941	CDK2	S162	V161I	161	Missense	proximal	-1	no	12.164	12.190	EPSD	TCGA;ICGC;COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	P23771	GATA3	P24941	CDK2	S162	P157T	157	Missense	distal	-5	no	12.164	12.163	EPSD	TCGA;ICGC;COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	P23771	GATA3	P24941	CDK2	S162	P165T	165	Missense	distal	3	no	12.164	12.050	EPSD	TCGA;ICGC;COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	P23771	GATA3	P24941	CDK2	S162	S166L	166	Missense	distal	4	no	12.164	12.263	EPSD	TCGA;ICGC;COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	P23771	GATA3	P24941	CDK2	T169	A176D	176	Missense	distal	7	no	13.814	14.116	EPSD	TCGA;ICGC;COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	P23771	GATA3	P24941	CDK2	T169	P165T	165	Missense	distal	-4	no	13.814	13.980	EPSD	TCGA;ICGC;COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	P23771	GATA3	P24941	CDK2	T169	A176T	176	Missense	distal	7	no	13.814	13.125	EPSD	TCGA;ICGC;COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	P23771	GATA3	P24941	CDK2	T169	S166L	166	Missense	distal	-3	no	13.814	13.647	EPSD	TCGA;ICGC;COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	P23771	GATA3	P24941	CDK2	S243	S243F	243	Missense	central	0	yes	12.847	0.000	EPSD	TCGA;ICGC;COSMIC	8.148	Loss
CMGC_CDK_CDK2_CDK2_ST	Q9UGP5	POLL	P24941	CDK2	S167	A165T	165	Missense	proximal	-2	no	13.863	13.813	EPSD;PhosphoSitePlus	TCGA;ICGC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	Q9UGP5	POLL	P24941	CDK2	S167	P168S	168	Missense	proximal	1	no	13.863	2.597	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	8.148	Loss
CMGC_CDK_CDK2_CDK2_ST	Q9UGP5	POLL	P24941	CDK2	S230	P231L	231	Missense	proximal	1	no	12.875	3.054	EPSD;PhosphoSitePlus	TCGA;COSMIC	8.148	Loss
CMGC_CDK_CDK2_CDK2_ST	Q9UGP5	POLL	P24941	CDK2	S230	A232T	232	Missense	proximal	2	no	12.875	12.673	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	Q9UGP5	POLL	P24941	CDK2	T553	P554L	554	Missense	proximal	1	no	15.305	5.484	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	8.148	Loss
CMGC_CDK_CDK2_CDK2_ST	Q9UGP5	POLL	P24941	CDK2	T553	G548S	548	Missense	distal	-5	no	15.305	15.181	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	O94761	RECQL4	P24941	CDK2	S89	P94S	94	Missense	distal	5	no	15.429	15.328	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	O94761	RECQL4	P24941	CDK2	T93	P94S	94	Missense	proximal	1	no	17.099	5.833	EPSD	TCGA;ICGC;COSMIC	8.148	Loss
CMGC_CDK_CDK2_CDK2_ST	O94761	RECQL4	P24941	CDK2	T139	G146V	146	Missense	distal	7	no	13.183	12.771	EPSD	TCGA;ICGC;COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	O94761	RECQL4	P24941	CDK2	T139	S138F	138	Missense	proximal	-1	no	13.183	14.439	EPSD	TCGA;ICGC;COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	O94761	RECQL4	P24941	CDK2	T139	S135Y	135	Missense	distal	-4	no	13.183	13.294	EPSD	TCGA;ICGC;COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	O94761	RECQL4	P24941	CDK2	S251	G250R	250	Missense	proximal	-1	no	14.684	14.206	PhosphoSitePlus;EPSD	TCGA;ICGC;COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	O94761	RECQL4	P24941	CDK2	S251	R248C	248	Missense	distal	-3	no	14.684	14.598	PhosphoSitePlus;EPSD	TCGA;ICGC;GDSC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	O94761	RECQL4	P24941	CDK2	S323	S323N	323	Missense	central	0	yes	13.471	0.000	EPSD	TCGA;ICGC;COSMIC	8.148	Loss
CMGC_CDK_CDK2_CDK2_ST	O94761	RECQL4	P24941	CDK2	S326	K332N	332	Missense	distal	6	no	11.151	11.147	EPSD	TCGA;ICGC;COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	O94761	RECQL4	P24941	CDK2	S326	S323N	323	Missense	distal	-3	no	11.151	11.077	EPSD	TCGA;ICGC;COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	O94761	RECQL4	P24941	CDK2	S732	A726V	726	Missense	distal	-6	no	8.754	8.757	EPSD	TCGA;ICGC;COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	Q9NSV4	DIAPH3	P24941	CDK2	T19	A12V	12	Missense	distal	-7	no	14.980	14.835	PhosphoSitePlus	TCGA;ICGC;COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	Q9NSV4	DIAPH3	P24941	CDK2	T19	G14S	14	Missense	distal	-5	no	14.980	14.856	PhosphoSitePlus	TCGA;ICGC;COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	Q9NSV4	DIAPH3	P24941	CDK2	S48	P50S	50	Missense	proximal	2	no	8.475	8.541	EPSD	TCGA;ICGC;COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	Q9NSV4	DIAPH3	P24941	CDK2	S175	S175L	175	Missense	central	0	yes	14.160	0.000	EPSD	TCGA;ICGC;COSMIC	8.148	Loss
CMGC_CDK_CDK2_CDK2_ST	Q9NSV4	DIAPH3	P24941	CDK2	S175	F179S	179	Missense	distal	4	no	14.160	14.356	EPSD	TCGA;ICGC;COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	Q9NSV4	DIAPH3	P24941	CDK2	S175	R172Q	172	Missense	distal	-3	no	14.160	14.029	EPSD	TCGA;ICGC;COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	Q9NSV4	DIAPH3	P24941	CDK2	S607	P611L	611	Missense	distal	4	no	8.173	8.285	EPSD	TCGA;ICGC;COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	Q9NSV4	DIAPH3	P24941	CDK2	S607	P611H	611	Missense	distal	4	no	8.173	7.935	EPSD	TCGA;ICGC;COSMIC	8.148	Loss
CMGC_CDK_CDK2_CDK2_ST	Q9NSV4	DIAPH3	P24941	CDK2	S607	R603W	603	Missense	distal	-4	no	8.173	7.416	EPSD	TCGA;ICGC;COSMIC	8.148	Loss
CMGC_CDK_CDK2_CDK2_ST	Q9NSV4	DIAPH3	P24941	CDK2	S607	P613L	613	Missense	distal	6	no	8.173	8.175	EPSD	TCGA;ICGC;COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	Q9NSV4	DIAPH3	P24941	CDK2	S624	P626S	626	Missense	proximal	2	no	14.198	14.265	EPSD	TCGA;ICGC;COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	Q9NSV4	DIAPH3	P24941	CDK2	S624	G621R	621	Missense	distal	-3	no	14.198	14.284	EPSD	TCGA;ICGC;COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	Q9NSV4	DIAPH3	P24941	CDK2	S1093	R1098W	1098	Missense	distal	5	no	14.173	14.340	EPSD	TCGA;ICGC;COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	Q9NSV4	DIAPH3	P24941	CDK2	S1093	R1089W	1089	Missense	distal	-4	no	14.173	13.416	EPSD	TCGA;ICGC;COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	Q9NSV4	DIAPH3	P24941	CDK2	S1096	R1098W	1098	Missense	proximal	2	no	10.135	10.232	EPSD	TCGA;ICGC;COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	Q9NSV4	DIAPH3	P24941	CDK2	S1096	V1103F	1103	Missense	distal	7	no	10.135	10.578	EPSD	TCGA;ICGC;COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	Q9NSV4	DIAPH3	P24941	CDK2	S1096	R1089W	1089	Missense	distal	-7	no	10.135	10.306	EPSD	TCGA;ICGC;COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	Q9NSV4	DIAPH3	P24941	CDK2	T1130	L1136P	1136	Missense	distal	6	no	13.879	13.878	EPSD	TCGA;ICGC;COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	P28324	ELK4	P24941	CDK2	S180	E177D	177	Missense	distal	-3	no	12.829	12.719	EPSD	TCGA;ICGC;COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	P28324	ELK4	P24941	CDK2	S180	S180F	180	Missense	central	0	yes	12.829	0.000	EPSD	TCGA;ICGC;COSMIC	8.148	Loss
CMGC_CDK_CDK2_CDK2_ST	P28324	ELK4	P24941	CDK2	T185	K190R	190	Missense	distal	5	no	12.322	12.483	EPSD	TCGA;ICGC;COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	P28324	ELK4	P24941	CDK2	T185	S180F	180	Missense	distal	-5	no	12.322	12.439	EPSD	TCGA;ICGC;COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	P28324	ELK4	P24941	CDK2	T194	K190R	190	Missense	distal	-4	no	14.015	13.853	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	P28324	ELK4	P24941	CDK2	S215	S217C	217	Missense	proximal	2	no	12.434	12.513	EPSD	TCGA;ICGC;COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	P28324	ELK4	P24941	CDK2	S215	E219Q	219	Missense	distal	4	no	12.434	12.478	EPSD	TCGA;ICGC;COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	P28324	ELK4	P24941	CDK2	S215	I214F	214	Missense	proximal	-1	no	12.434	13.237	EPSD	TCGA;ICGC;COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	P28324	ELK4	P24941	CDK2	S215	G211D	211	Missense	distal	-4	no	12.434	13.279	EPSD	TCGA;ICGC;COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	P28324	ELK4	P24941	CDK2	S387	R390K	390	Missense	distal	3	no	15.345	16.334	PhosphoSitePlus;EPSD	TCGA;ICGC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	P28324	ELK4	P24941	CDK2	T420	D416G	416	Missense	distal	-4	no	13.564	12.719	EPSD	TCGA;ICGC;COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	P28324	ELK4	P24941	CDK2	T420	P418L	418	Missense	proximal	-2	no	13.564	13.339	EPSD	TCGA;ICGC;COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	P28324	ELK4	P24941	CDK2	S425	P418L	418	Missense	distal	-7	no	16.192	16.197	EPSD	TCGA;ICGC;COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	P03372	ESR1	P24941	CDK2	S106	P113S	113	Missense	distal	7	no	12.768	12.616	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	P03372	ESR1	P24941	CDK2	S118	P113S	113	Missense	distal	-5	no	12.997	12.953	PhosphoSitePlus;EPSD	TCGA;ICGC;COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	P03372	ESR1	P24941	CDK2	S294	W292R	292	Missense	proximal	-2	no	12.927	13.427	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	P03372	ESR1	P24941	CDK2	S294	I298M	298	Missense	distal	4	no	12.927	12.535	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	P03372	ESR1	P24941	CDK2	S294	L291I	291	Missense	distal	-3	no	12.927	13.018	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	P03372	ESR1	P24941	CDK2	S578	T585M	585	Missense	distal	7	no	7.700	8.549	EPSD	TCGA;ICGC;COSMIC	8.148	Gain
CMGC_CDK_CDK2_CDK2_ST	Q12778	FOXO1	P24941	CDK2	S249	A255T	255	Missense	distal	6	no	12.577	12.588	PhosphoSitePlus	TCGA;ICGC;COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	Q12778	FOXO1	P24941	CDK2	S249	R251S	251	Missense	proximal	2	no	12.577	12.484	PhosphoSitePlus	TCGA;ICGC;COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	Q12778	FOXO1	P24941	CDK2	S249	P250L	250	Missense	proximal	1	no	12.577	2.756	PhosphoSitePlus	TCGA;ICGC;COSMIC	8.148	Loss
CMGC_CDK_CDK2_CDK2_ST	Q12778	FOXO1	P24941	CDK2	S249	P250S	250	Missense	proximal	1	no	12.577	1.311	PhosphoSitePlus	TCGA;ICGC;COSMIC	8.148	Loss
CMGC_CDK_CDK2_CDK2_ST	Q12778	FOXO1	P24941	CDK2	S249	S249Y	249	Missense	central	0	yes	12.577	0.000	PhosphoSitePlus	TCGA;ICGC;COSMIC	8.148	Loss
CMGC_CDK_CDK2_CDK2_ST	Q12778	FOXO1	P24941	CDK2	S279	S279F	279	Missense	central	0	yes	8.190	0.000	EPSD	TCGA;ICGC;COSMIC	8.148	Loss
CMGC_CDK_CDK2_CDK2_ST	Q12778	FOXO1	P24941	CDK2	S287	G289E	289	Missense	proximal	2	no	15.718	15.697	EPSD	TCGA;ICGC;COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	Q12778	FOXO1	P24941	CDK2	S290	G289E	289	Missense	proximal	-1	no	8.968	8.704	EPSD	TCGA;ICGC;COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	Q12778	FOXO1	P24941	CDK2	S298	P299S	299	Missense	proximal	1	no	12.278	1.012	EPSD	TCGA;ICGC;COSMIC	8.148	Loss
CMGC_CDK_CDK2_CDK2_ST	Q12778	FOXO1	P24941	CDK2	S329	M332I	332	Missense	distal	3	no	11.834	11.406	EPSD	TCGA;COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	Q12778	FOXO1	P24941	CDK2	S329	G326R	326	Missense	distal	-3	no	11.834	11.920	EPSD	TCGA;ICGC;COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	Q12778	FOXO1	P24941	CDK2	S329	S329L	329	Missense	central	0	yes	11.834	0.000	EPSD	TCGA;ICGC;COSMIC	8.148	Loss
CMGC_CDK_CDK2_CDK2_ST	Q12778	FOXO1	P24941	CDK2	S329	T323A	323	Missense	distal	-6	no	11.834	11.833	EPSD	TCGA;ICGC;COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	Q12778	FOXO1	P24941	CDK2	S383	L387I	387	Missense	distal	4	no	15.642	15.501	EPSD	TCGA;ICGC;COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	Q12778	FOXO1	P24941	CDK2	S383	L378I	378	Missense	distal	-5	no	15.642	15.669	EPSD	TCGA;ICGC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	Q12778	FOXO1	P24941	CDK2	S394	L387I	387	Missense	distal	-7	no	13.914	14.103	EPSD	TCGA;ICGC;COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	Q12778	FOXO1	P24941	CDK2	T402	S406L	406	Missense	distal	4	no	11.030	11.128	EPSD	TCGA;ICGC;COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	Q12778	FOXO1	P24941	CDK2	T402	A408V	408	Missense	distal	6	no	11.030	11.032	EPSD	TCGA;ICGC;COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	Q12778	FOXO1	P24941	CDK2	T402	T402M	402	Missense	central	0	yes	11.030	0.000	EPSD	TCGA;ICGC;COSMIC	8.148	Loss
CMGC_CDK_CDK2_CDK2_ST	Q12778	FOXO1	P24941	CDK2	T402	A408T	408	Missense	distal	6	no	11.030	11.042	EPSD	TCGA;ICGC;COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	Q12778	FOXO1	P24941	CDK2	S416	L414S	414	Missense	proximal	-2	no	14.544	14.117	EPSD	TCGA;ICGC;COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	Q12778	FOXO1	P24941	CDK2	S418	L414S	414	Missense	distal	-4	no	13.514	13.927	EPSD	TCGA;ICGC;COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	P12268	IMPDH2	P24941	CDK2	S122	V127M	127	Missense	distal	5	no	13.332	13.673	PhosphoSitePlus	TCGA;ICGC;COSMIC;GDSC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	O75533	SF3B1	P24941	CDK2	S129	R124L	124	Missense	distal	-5	no	18.222	18.187	EPSD	TCGA;ICGC;COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	O75533	SF3B1	P24941	CDK2	S129	P135S	135	Missense	distal	6	no	18.222	18.223	EPSD	TCGA;ICGC;COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	O75533	SF3B1	P24941	CDK2	S129	R124Q	124	Missense	distal	-5	no	18.222	18.175	EPSD	TCGA;ICGC;COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	O75533	SF3B1	P24941	CDK2	T142	P135S	135	Missense	distal	-7	no	14.904	14.724	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	O75533	SF3B1	P24941	CDK2	T142	G139E	139	Missense	distal	-3	no	14.904	14.975	EPSD;PhosphoSitePlus	TCGA;ICGC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	O75533	SF3B1	P24941	CDK2	T142	M147V	147	Missense	distal	5	no	14.904	14.564	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	O75533	SF3B1	P24941	CDK2	T207	Q206E	206	Missense	proximal	-1	no	14.375	15.467	EPSD	TCGA;ICGC;COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	O75533	SF3B1	P24941	CDK2	T207	Q206R	206	Missense	proximal	-1	no	14.375	15.253	EPSD	TCGA;ICGC;COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	O75533	SF3B1	P24941	CDK2	T211	Q206E	206	Missense	distal	-5	no	15.661	15.698	PhosphoSitePlus;EPSD	TCGA;ICGC;COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	O75533	SF3B1	P24941	CDK2	T211	Q206R	206	Missense	distal	-5	no	15.661	15.707	PhosphoSitePlus;EPSD	TCGA;ICGC;COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	O75533	SF3B1	P24941	CDK2	T223	P228S	228	Missense	distal	5	no	16.464	16.363	EPSD	TCGA;ICGC;COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	O75533	SF3B1	P24941	CDK2	T223	S229F	229	Missense	distal	6	no	16.464	16.445	EPSD	TCGA;ICGC;COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	O75533	SF3B1	P24941	CDK2	T223	Q220K	220	Missense	distal	-3	no	16.464	16.365	EPSD	TCGA;ICGC;COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	O75533	SF3B1	P24941	CDK2	T227	R231I	231	Missense	distal	4	no	13.378	13.469	EPSD	TCGA;ICGC;COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	O75533	SF3B1	P24941	CDK2	T227	P228S	228	Missense	proximal	1	no	13.378	2.112	EPSD	TCGA;ICGC;COSMIC	8.148	Loss
CMGC_CDK_CDK2_CDK2_ST	O75533	SF3B1	P24941	CDK2	T227	S229F	229	Missense	proximal	2	no	13.378	13.562	EPSD	TCGA;ICGC;COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	O75533	SF3B1	P24941	CDK2	T227	Q220K	220	Missense	distal	-7	no	13.378	13.374	EPSD	TCGA;ICGC;COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	O75533	SF3B1	P24941	CDK2	T235	R231I	231	Missense	distal	-4	no	15.794	15.887	EPSD	TCGA;ICGC;COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	O75533	SF3B1	P24941	CDK2	T235	P228S	228	Missense	distal	-7	no	15.794	15.615	EPSD	TCGA;ICGC;COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	O75533	SF3B1	P24941	CDK2	T235	S229F	229	Missense	distal	-6	no	15.794	15.800	EPSD	TCGA;ICGC;COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	O75533	SF3B1	P24941	CDK2	T235	P236S	236	Missense	proximal	1	no	15.794	4.529	EPSD	TCGA;ICGC	8.148	Loss
CMGC_CDK_CDK2_CDK2_ST	O75533	SF3B1	P24941	CDK2	T248	D255N	255	Missense	distal	7	no	14.377	13.597	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	O75533	SF3B1	P24941	CDK2	T257	D255N	255	Missense	proximal	-2	no	15.238	14.029	EPSD	TCGA;ICGC;COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	O75533	SF3B1	P24941	CDK2	T257	P258L	258	Missense	proximal	1	no	15.238	5.417	EPSD	TCGA	8.148	Loss
CMGC_CDK_CDK2_CDK2_ST	O75533	SF3B1	P24941	CDK2	S259	D255N	255	Missense	distal	-4	no	8.642	8.254	EPSD	TCGA;ICGC;COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	O75533	SF3B1	P24941	CDK2	S259	P258L	258	Missense	proximal	-1	no	8.642	8.463	EPSD	TCGA	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	O75533	SF3B1	P24941	CDK2	T261	D255N	255	Missense	distal	-6	no	14.208	14.209	EPSD	TCGA;ICGC;COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	O75533	SF3B1	P24941	CDK2	T261	P258L	258	Missense	distal	-3	no	14.208	14.137	EPSD	TCGA	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	O75533	SF3B1	P24941	CDK2	T261	T267N	267	Missense	distal	6	no	14.208	14.204	EPSD	TCGA;ICGC;COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	O75533	SF3B1	P24941	CDK2	T267	T267N	267	Missense	central	0	yes	15.272	0.000	EPSD	TCGA;ICGC;COSMIC	8.148	Loss
CMGC_CDK_CDK2_CDK2_ST	O75533	SF3B1	P24941	CDK2	T267	P274L	274	Missense	distal	7	no	15.272	15.302	EPSD	TCGA;ICGC;COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	O75533	SF3B1	P24941	CDK2	T273	A277S	277	Missense	distal	4	no	16.321	16.295	EPSD	TCGA;ICGC;COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	O75533	SF3B1	P24941	CDK2	T273	P274L	274	Missense	proximal	1	no	16.321	6.501	EPSD	TCGA;ICGC;COSMIC	8.148	Loss
CMGC_CDK_CDK2_CDK2_ST	O75533	SF3B1	P24941	CDK2	T278	A277S	277	Missense	proximal	-1	no	16.046	15.845	EPSD	TCGA;ICGC;COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	O75533	SF3B1	P24941	CDK2	T278	P274L	274	Missense	distal	-4	no	16.046	15.987	EPSD	TCGA;ICGC;COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	O75533	SF3B1	P24941	CDK2	T296	R292K	292	Missense	distal	-4	no	15.789	15.951	EPSD	TCGA;ICGC;COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	O75533	SF3B1	P24941	CDK2	T303	S308R	308	Missense	distal	5	no	15.957	16.164	EPSD	TCGA;ICGC;COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	O75533	SF3B1	P24941	CDK2	S308	S308R	308	Missense	central	0	yes	8.909	0.000	EPSD	TCGA;ICGC;COSMIC	8.148	Loss
CMGC_CDK_CDK2_CDK2_ST	O75533	SF3B1	P24941	CDK2	S308	R315Q	315	Missense	distal	7	no	8.909	8.265	EPSD	TCGA;ICGC;COSMIC;GDSC;CCLE	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	O75533	SF3B1	P24941	CDK2	T313	S308R	308	Missense	distal	-5	no	17.125	17.216	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	O75533	SF3B1	P24941	CDK2	T313	T316A	316	Missense	distal	3	no	17.125	16.727	EPSD;PhosphoSitePlus	TCGA;ICGC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	O75533	SF3B1	P24941	CDK2	T313	R315Q	315	Missense	proximal	2	no	17.125	17.025	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC;GDSC;CCLE	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	O75533	SF3B1	P24941	CDK2	T326	D321V	321	Missense	distal	-5	no	13.836	13.809	EPSD	TCGA;ICGC;COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	O75533	SF3B1	P24941	CDK2	T326	I323V	323	Missense	distal	-3	no	13.836	13.959	EPSD	TCGA;ICGC;COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	O75533	SF3B1	P24941	CDK2	T326	P327R	327	Missense	proximal	1	no	13.836	4.038	EPSD	TCGA;ICGC;COSMIC	8.148	Loss
CMGC_CDK_CDK2_CDK2_ST	O75533	SF3B1	P24941	CDK2	T328	D321V	321	Missense	distal	-7	no	11.537	11.315	EPSD	TCGA;ICGC;COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	O75533	SF3B1	P24941	CDK2	T328	I323V	323	Missense	distal	-5	no	11.537	11.529	EPSD	TCGA;ICGC;COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	O75533	SF3B1	P24941	CDK2	T328	P327R	327	Missense	proximal	-1	no	11.537	12.107	EPSD	TCGA;ICGC;COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	O75533	SF3B1	P24941	CDK2	T328	R334I	334	Missense	distal	6	no	11.537	11.553	EPSD	TCGA;ICGC;COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	O75533	SF3B1	P24941	CDK2	T341	R334I	334	Missense	distal	-7	no	15.136	14.987	EPSD	TCGA;ICGC;COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	O75533	SF3B1	P24941	CDK2	T350	P351L	351	Missense	proximal	1	no	11.465	1.644	EPSD	TCGA;ICGC;COSMIC	8.148	Loss
CMGC_CDK_CDK2_CDK2_ST	O75533	SF3B1	P24941	CDK2	T350	P351S	351	Missense	proximal	1	no	11.465	0.199	EPSD	TCGA;ICGC;COSMIC	8.148	Loss
CMGC_CDK_CDK2_CDK2_ST	O75533	SF3B1	P24941	CDK2	T354	P351L	351	Missense	distal	-3	no	19.286	19.215	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	O75533	SF3B1	P24941	CDK2	T354	P351S	351	Missense	distal	-3	no	19.286	19.381	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	O75533	SF3B1	P24941	CDK2	T358	P351L	351	Missense	distal	-7	no	13.094	13.099	EPSD	TCGA;ICGC;COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	O75533	SF3B1	P24941	CDK2	T358	P351S	351	Missense	distal	-7	no	13.094	12.914	EPSD	TCGA;ICGC;COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	O75533	SF3B1	P24941	CDK2	T362	A368D	368	Missense	distal	6	no	15.139	15.128	EPSD	TCGA;ICGC;COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	O75533	SF3B1	P24941	CDK2	T362	A368T	368	Missense	distal	6	no	15.139	15.151	EPSD	TCGA;ICGC;COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	O75533	SF3B1	P24941	CDK2	T369	P370L	370	Missense	proximal	1	no	11.508	1.687	EPSD	TCGA;ICGC;COSMIC	8.148	Loss
CMGC_CDK_CDK2_CDK2_ST	O75533	SF3B1	P24941	CDK2	T369	A368D	368	Missense	proximal	-1	no	11.508	12.534	EPSD	TCGA;ICGC;COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	O75533	SF3B1	P24941	CDK2	T369	A368T	368	Missense	proximal	-1	no	11.508	11.515	EPSD	TCGA;ICGC;COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	O75533	SF3B1	P24941	CDK2	T371	P370L	370	Missense	proximal	-1	no	15.690	15.510	EPSD	TCGA;ICGC;COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	O75533	SF3B1	P24941	CDK2	T371	A368D	368	Missense	distal	-3	no	15.690	15.813	EPSD	TCGA;ICGC;COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	O75533	SF3B1	P24941	CDK2	T371	A368T	368	Missense	distal	-3	no	15.690	15.709	EPSD	TCGA;ICGC;COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	O75533	SF3B1	P24941	CDK2	T371	S377N	377	Missense	distal	6	no	15.690	15.692	EPSD	TCGA;ICGC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	O75533	SF3B1	P24941	CDK2	T379	S377N	377	Missense	proximal	-2	no	15.663	14.972	EPSD	TCGA;ICGC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	O75533	SF3B1	P24941	CDK2	T426	R425Q	425	Missense	proximal	-1	no	17.069	16.191	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	O75533	SF3B1	P24941	CDK2	T426	A433G	433	Missense	distal	7	no	17.069	17.354	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	O75533	SF3B1	P24941	CDK2	T434	A433G	433	Missense	proximal	-1	no	12.552	13.871	EPSD	TCGA;ICGC;COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	O75533	SF3B1	P24941	CDK2	T436	A433G	433	Missense	distal	-3	no	14.000	14.162	EPSD	TCGA;ICGC;COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	O75533	SF3B1	P24941	CDK2	S488	E490K	490	Missense	proximal	2	no	14.281	14.043	EPSD	TCGA;ICGC;COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	O75533	SF3B1	P24941	CDK2	T508	L502F	502	Missense	distal	-6	no	13.239	13.243	EPSD	TCGA;ICGC;COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	O75533	SF3B1	P24941	CDK2	S541	S541P	541	Missense	central	0	yes	13.379	0.000	EPSD	TCGA;ICGC;COSMIC	8.148	Loss
CMGC_CDK_CDK2_CDK2_ST	O75533	SF3B1	P24941	CDK2	S541	L544P	544	Missense	distal	3	no	13.379	13.763	EPSD	TCGA;ICGC;COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	O75533	SF3B1	P24941	CDK2	T1021	N1026S	1026	Missense	distal	5	no	14.030	13.826	EPSD	TCGA;ICGC;COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	O75533	SF3B1	P24941	CDK2	T1021	R1019G	1019	Missense	proximal	-2	no	14.030	14.523	EPSD	TCGA;ICGC;COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	O75533	SF3B1	P24941	CDK2	T1021	D1015G	1015	Missense	distal	-6	no	14.030	14.034	EPSD	TCGA;ICGC;COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	O75533	SF3B1	P24941	CDK2	T1170	D1164Y	1164	Missense	distal	-6	no	12.782	12.784	EPSD	TCGA;ICGC;COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	O75533	SF3B1	P24941	CDK2	T1170	D1175Y	1175	Missense	distal	5	no	12.782	12.682	EPSD	TCGA;ICGC;COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	O75533	SF3B1	P24941	CDK2	T1170	V1169I	1169	Missense	proximal	-1	no	12.782	12.809	EPSD	TCGA;ICGC;COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	P12272	PTHLH	P24941	CDK2	S85	S82C	82	Missense	distal	-3	no	14.581	14.588	EPSD	TCGA;ICGC;COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	P12272	PTHLH	P24941	CDK2	T121	G123R	123	Missense	proximal	2	no	16.482	16.523	PhosphoSitePlus	TCGA;ICGC;COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	P12272	PTHLH	P24941	CDK2	T121	G123E	123	Missense	proximal	2	no	16.482	16.461	PhosphoSitePlus	TCGA;ICGC;COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	P12272	PTHLH	P24941	CDK2	T121	P118L	118	Missense	distal	-3	no	16.482	16.411	PhosphoSitePlus	TCGA;ICGC;COSMIC;GDSC;CCLE	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	Q99741	CDC6	P24941	CDK2	S45	S45C	45	Missense	central	0	yes	15.739	0.000	EPSD	TCGA;ICGC;COSMIC	8.148	Loss
CMGC_CDK_CDK2_CDK2_ST	Q99741	CDC6	P24941	CDK2	S88	H87Q	87	Missense	proximal	-1	no	8.365	7.938	EPSD	TCGA;ICGC;COSMIC	8.148	Loss
CMGC_CDK_CDK2_CDK2_ST	Q99741	CDC6	P24941	CDK2	S88	E82Q	82	Missense	distal	-6	no	8.365	8.366	EPSD	TCGA;ICGC;COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	Q99741	CDC6	P24941	CDK2	S88	R94Q	94	Missense	distal	6	no	8.365	8.387	EPSD	TCGA;ICGC;COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	Q99741	CDC6	P24941	CDK2	S88	K92N	92	Missense	distal	4	no	8.365	7.943	EPSD	TCGA;ICGC	8.148	Loss
CMGC_CDK_CDK2_CDK2_ST	Q99741	CDC6	P24941	CDK2	S106	K105R	105	Missense	proximal	-1	no	14.184	14.855	PhosphoSitePlus;EPSD	TCGA;ICGC;COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	Q99741	CDC6	P24941	CDK2	S415	E416K	416	Missense	proximal	1	no	8.578	0.094	EPSD	TCGA;ICGC;COSMIC	8.148	Loss
CMGC_CDK_CDK2_CDK2_ST	Q99741	CDC6	P24941	CDK2	S415	S415P	415	Missense	central	0	yes	8.578	0.000	EPSD	TCGA;ICGC;COSMIC	8.148	Loss
CMGC_CDK_CDK2_CDK2_ST	Q99741	CDC6	P24941	CDK2	S419	E416K	416	Missense	distal	-3	no	14.406	14.190	EPSD	TCGA;ICGC;COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	Q99741	CDC6	P24941	CDK2	S419	S415P	415	Missense	distal	-4	no	14.406	14.051	EPSD	TCGA;ICGC;COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	P10644	PRKAR1A	P24941	CDK2	S83	P85T	85	Missense	proximal	2	no	13.867	13.690	PhosphoSitePlus	TCGA;ICGC;COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	P10644	PRKAR1A	P24941	CDK2	S83	S77L	77	Missense	distal	-6	no	13.867	13.868	PhosphoSitePlus	TCGA;ICGC;COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	P10644	PRKAR1A	P24941	CDK2	S83	E81D	81	Missense	proximal	-2	no	13.867	14.848	PhosphoSitePlus	TCGA;ICGC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	P10644	PRKAR1A	P24941	CDK2	S251	K252Q	252	Missense	proximal	1	no	-1.061	8.677	EPSD	TCGA;ICGC	8.148	Gain
CMGC_CDK_CDK2_CDK2_ST	Q15003	NCAPH	P24941	CDK2	S28	A26V	26	Missense	proximal	-2	no	15.447	14.781	EPSD	TCGA;COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	Q15003	NCAPH	P24941	CDK2	T49	D54A	54	Missense	distal	5	no	14.050	13.886	PhosphoSitePlus	TCGA;COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	Q15003	NCAPH	P24941	CDK2	T49	E53K	53	Missense	distal	4	no	14.050	14.435	PhosphoSitePlus	TCGA;COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	Q15003	NCAPH	P24941	CDK2	T49	P50S	50	Missense	proximal	1	no	14.050	2.784	PhosphoSitePlus	TCGA;COSMIC	8.148	Loss
CMGC_CDK_CDK2_CDK2_ST	Q15003	NCAPH	P24941	CDK2	S81	R83H	83	Missense	proximal	2	no	13.361	13.280	EPSD	TCGA;COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	Q15003	NCAPH	P24941	CDK2	S81	D74Y	74	Missense	distal	-7	no	13.361	13.246	EPSD	TCGA;COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	Q15003	NCAPH	P24941	CDK2	S81	P82S	82	Missense	proximal	1	no	13.361	2.095	EPSD	TCGA;COSMIC	8.148	Loss
CMGC_CDK_CDK2_CDK2_ST	Q15003	NCAPH	P24941	CDK2	S87	D94E	94	Missense	distal	7	no	13.645	13.003	EPSD	TCGA;COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	Q15003	NCAPH	P24941	CDK2	S87	R83H	83	Missense	distal	-4	no	13.645	13.285	EPSD	TCGA;COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	Q15003	NCAPH	P24941	CDK2	S87	S92I	92	Missense	distal	5	no	13.645	13.839	EPSD	TCGA;COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	Q15003	NCAPH	P24941	CDK2	S87	P82S	82	Missense	distal	-5	no	13.645	13.601	EPSD	TCGA;COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	Q15003	NCAPH	P24941	CDK2	S359	D360Y	360	Missense	proximal	1	no	8.546	1.291	EPSD	TCGA;COSMIC	8.148	Loss
CMGC_CDK_CDK2_CDK2_ST	Q15003	NCAPH	P24941	CDK2	S432	T435I	435	Missense	distal	3	no	14.715	14.161	EPSD	TCGA;ICGC;COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	Q15003	NCAPH	P24941	CDK2	S457	K464E	464	Missense	distal	7	no	8.836	9.166	EPSD	TCGA;COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	Q15003	NCAPH	P24941	CDK2	S457	D454Y	454	Missense	distal	-3	no	8.836	8.886	EPSD	TCGA;COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	Q15003	NCAPH	P24941	CDK2	S457	R451H	451	Missense	distal	-6	no	8.836	8.837	EPSD	TCGA;ICGC;COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	Q15003	NCAPH	P24941	CDK2	S457	R450Q	450	Missense	distal	-7	no	8.836	8.449	EPSD	TCGA;ICGC;COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	Q15003	NCAPH	P24941	CDK2	S459	K464E	464	Missense	distal	5	no	9.482	9.615	EPSD	TCGA;COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	Q15003	NCAPH	P24941	CDK2	S459	D454Y	454	Missense	distal	-5	no	9.482	9.449	EPSD	TCGA;COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	Q15003	NCAPH	P24941	CDK2	S465	K464E	464	Missense	proximal	-1	no	8.076	8.961	EPSD	TCGA;COSMIC	8.148	Gain
CMGC_CDK_CDK2_CDK2_ST	Q15003	NCAPH	P24941	CDK2	S589	P582L	582	Missense	distal	-7	no	15.135	15.141	EPSD	TCGA;ICGC;COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	Q15003	NCAPH	P24941	CDK2	T605	Q601H	601	Missense	distal	-4	no	14.004	13.619	EPSD	TCGA;ICGC;COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	Q15003	NCAPH	P24941	CDK2	T605	P606S	606	Missense	proximal	1	no	14.004	2.738	EPSD	TCGA;ICGC;COSMIC	8.148	Loss
CMGC_CDK_CDK2_CDK2_ST	Q92698	RAD54L	P24941	CDK2	T31	P32H	32	Missense	proximal	1	no	16.646	9.888	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	Q92698	RAD54L	P24941	CDK2	S49	L55F	55	Missense	distal	6	no	16.250	16.231	PhosphoSitePlus;EPSD	TCGA;ICGC;COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	P30304	CDC25A	P24941	CDK2	S88	D87Y	87	Missense	proximal	-1	no	14.456	14.139	EPSD	TCGA;ICGC;COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	P30304	CDC25A	P24941	CDK2	S88	P89L	89	Missense	proximal	1	no	14.456	4.635	EPSD	TCGA;ICGC;COSMIC	8.148	Loss
CMGC_CDK_CDK2_CDK2_ST	P30304	CDC25A	P24941	CDK2	S88	P91S	91	Missense	distal	3	no	14.456	14.490	EPSD	TCGA;ICGC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	P30304	CDC25A	P24941	CDK2	S116	R121S	121	Missense	distal	5	no	13.761	13.554	EPSD	TCGA;ICGC;COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	P30304	CDC25A	P24941	CDK2	S116	L119V	119	Missense	distal	3	no	13.761	14.753	EPSD	TCGA;ICGC;COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	P30304	CDC25A	P24941	CDK2	S116	P117S	117	Missense	proximal	1	no	13.761	2.495	EPSD	TCGA;ICGC;COSMIC	8.148	Loss
CMGC_CDK_CDK2_CDK2_ST	P30304	CDC25A	P24941	CDK2	S116	L113F	113	Missense	distal	-3	no	13.761	14.019	EPSD	TCGA;ICGC;COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	P30304	CDC25A	P24941	CDK2	S261	N254Y	254	Missense	distal	-7	no	12.875	13.082	EPSD	TCGA;ICGC;COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	P30304	CDC25A	P24941	CDK2	S279	P284T	284	Missense	distal	5	no	8.255	8.230	EPSD	TCGA;ICGC;COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	P30304	CDC25A	P24941	CDK2	S279	R275K	275	Missense	distal	-4	no	8.255	8.417	EPSD	TCGA;ICGC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	P30304	CDC25A	P24941	CDK2	S283	P284T	284	Missense	proximal	1	no	15.804	5.847	PhosphoSitePlus	TCGA;ICGC;COSMIC	8.148	Loss
CMGC_CDK_CDK2_CDK2_ST	P30304	CDC25A	P24941	CDK2	S298	S298N	298	Missense	central	0	yes	13.338	0.000	EPSD	TCGA;ICGC;COSMIC	8.148	Loss
CMGC_CDK_CDK2_CDK2_ST	P30304	CDC25A	P24941	CDK2	S321	S317F	317	Missense	distal	-4	no	13.607	12.645	EPSD	TCGA;ICGC;COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	P30304	CDC25A	P24941	CDK2	S361	S367C	367	Missense	distal	6	no	12.936	12.921	EPSD	TCGA;ICGC;COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	P30304	CDC25A	P24941	CDK2	S361	P362L	362	Missense	proximal	1	no	12.936	3.115	EPSD	TCGA;ICGC;COSMIC	8.148	Loss
CMGC_CDK_CDK2_CDK2_ST	P30304	CDC25A	P24941	CDK2	S361	A366T	366	Missense	distal	5	no	12.936	12.900	EPSD	TCGA;ICGC;COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	P30304	CDC25A	P24941	CDK2	S361	Q355P	355	Missense	distal	-6	no	12.936	12.933	EPSD	TCGA;ICGC;COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	P30304	CDC25A	P24941	CDK2	S519	R520H	520	Missense	proximal	1	no	5.768	8.808	EPSD	TCGA;ICGC;COSMIC;GDSC;CCLE	8.148	Gain
CMGC_CDK_CDK2_CDK2_ST	P33981	TTK	P24941	CDK2	S37	L32V	32	Missense	distal	-5	no	8.595	8.615	EPSD	TCGA;ICGC;COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	P33981	TTK	P24941	CDK2	S49	V52A	52	Missense	distal	3	no	8.301	7.181	EPSD	TCGA;ICGC;COSMIC	8.148	Loss
CMGC_CDK_CDK2_CDK2_ST	P33981	TTK	P24941	CDK2	S281	T288I	288	Missense	distal	7	no	8.574	8.935	EPSD	TCGA;ICGC;COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	P33981	TTK	P24941	CDK2	S333	N326H	326	Missense	distal	-7	no	12.107	12.311	EPSD	TCGA;ICGC;COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	P33981	TTK	P24941	CDK2	S333	S329F	329	Missense	distal	-4	no	12.107	11.145	EPSD	TCGA;ICGC;COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	P33981	TTK	P24941	CDK2	S333	L327I	327	Missense	distal	-6	no	12.107	12.109	EPSD	TCGA;ICGC;COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	P33981	TTK	P24941	CDK2	S333	K336N	336	Missense	distal	3	no	12.107	8.837	EPSD	TCGA;ICGC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	P33981	TTK	P24941	CDK2	T453	S449Y	449	Missense	distal	-4	no	14.802	14.913	EPSD;PhosphoSitePlus	TCGA;COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	P33981	TTK	P24941	CDK2	T468	P469L	469	Missense	proximal	1	no	16.886	7.066	PhosphoSitePlus;EPSD	TCGA;COSMIC;GDSC	8.148	Loss
CMGC_CDK_CDK2_CDK2_ST	P33981	TTK	P24941	CDK2	T468	K472N	472	Missense	distal	4	no	16.886	16.465	PhosphoSitePlus;EPSD	TCGA	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	P33981	TTK	P24941	CDK2	S821	G814C	814	Missense	distal	-7	no	13.752	13.698	EPSD	TCGA;COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	P33981	TTK	P24941	CDK2	S821	S824F	824	Missense	distal	3	no	13.752	13.677	EPSD	TCGA;COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	P33981	TTK	P24941	CDK2	S821	L816R	816	Missense	distal	-5	no	13.752	13.787	EPSD	TCGA;COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	P33981	TTK	P24941	CDK2	S821	S821Y	821	Missense	central	0	yes	13.752	0.000	EPSD	TCGA;COSMIC	8.148	Loss
CMGC_CDK_CDK2_CDK2_ST	P33981	TTK	P24941	CDK2	S837	G839S	839	Missense	proximal	2	no	8.906	8.855	EPSD	TCGA;COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	Q53GL7	PARP10	P24941	CDK2	T101	P98S	98	Missense	distal	-3	no	14.904	14.999	PhosphoSitePlus	TCGA;COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	Q53GL7	PARP10	P24941	CDK2	T310	R317K	317	Missense	distal	7	no	9.528	8.752	EPSD	TCGA;COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	Q53GL7	PARP10	P24941	CDK2	S431	A427T	427	Missense	distal	-4	no	10.502	10.727	EPSD	TCGA;COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	Q53GL7	PARP10	P24941	CDK2	S431	A438V	438	Missense	distal	7	no	10.502	10.376	EPSD	TCGA;COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	Q53GL7	PARP10	P24941	CDK2	S663	L664P	664	Missense	proximal	1	no	4.892	14.713	EPSD	TCGA;COSMIC	8.148	Gain
CMGC_CDK_CDK2_CDK2_ST	Q53GL7	PARP10	P24941	CDK2	S1011	S1011F	1011	Missense	central	0	yes	13.328	0.000	EPSD	TCGA;ICGC;COSMIC	8.148	Loss
CMGC_CDK_CDK2_CDK2_ST	Q53ET0	CRTC2	P24941	CDK2	S90	R96Q	96	Missense	distal	6	no	10.698	10.720	EPSD	TCGA;ICGC;COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	Q53ET0	CRTC2	P24941	CDK2	S116	R119C	119	Missense	distal	3	no	14.667	8.303	EPSD	TCGA;ICGC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	Q53ET0	CRTC2	P24941	CDK2	S128	Y134H	134	Missense	distal	6	no	15.585	15.588	EPSD	TCGA;ICGC;COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	Q53ET0	CRTC2	P24941	CDK2	S128	S127N	127	Missense	proximal	-1	no	15.585	15.982	EPSD	TCGA;ICGC;COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	Q53ET0	CRTC2	P24941	CDK2	S131	Y134H	134	Missense	distal	3	no	13.335	15.102	EPSD	TCGA;ICGC;COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	Q53ET0	CRTC2	P24941	CDK2	S131	S127N	127	Missense	distal	-4	no	13.335	13.118	EPSD	TCGA;ICGC;COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	Q53ET0	CRTC2	P24941	CDK2	S136	Y134H	134	Missense	proximal	-2	no	14.361	13.916	EPSD	TCGA;ICGC;COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	Q53ET0	CRTC2	P24941	CDK2	S183	T187A	187	Missense	distal	4	no	12.820	12.578	EPSD	TCGA;ICGC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	Q53ET0	CRTC2	P24941	CDK2	S183	T187I	187	Missense	distal	4	no	12.820	12.509	EPSD	TCGA;ICGC;COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	Q53ET0	CRTC2	P24941	CDK2	T192	T187A	187	Missense	distal	-5	no	12.888	12.914	EPSD	TCGA;ICGC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	Q53ET0	CRTC2	P24941	CDK2	T192	T187I	187	Missense	distal	-5	no	12.888	12.928	EPSD	TCGA;ICGC;COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	Q53ET0	CRTC2	P24941	CDK2	S336	D330H	330	Missense	distal	-6	no	12.451	12.456	EPSD	TCGA;ICGC;COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	Q53ET0	CRTC2	P24941	CDK2	S336	S339N	339	Missense	distal	3	no	12.451	11.854	EPSD	TCGA;ICGC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	Q53ET0	CRTC2	P24941	CDK2	S358	Q353R	353	Missense	distal	-5	no	15.872	15.918	EPSD	TCGA;COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	Q53ET0	CRTC2	P24941	CDK2	S358	Q360R	360	Missense	proximal	2	no	15.872	15.971	EPSD	TCGA;ICGC;COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	Q53ET0	CRTC2	P24941	CDK2	S368	S375Y	375	Missense	distal	7	no	7.913	8.334	EPSD	TCGA;ICGC;COSMIC	8.148	Gain
CMGC_CDK_CDK2_CDK2_ST	Q53ET0	CRTC2	P24941	CDK2	S368	S375F	375	Missense	distal	7	no	7.913	8.767	EPSD	TCGA;ICGC;COSMIC	8.148	Gain
CMGC_CDK_CDK2_CDK2_ST	Q53ET0	CRTC2	P24941	CDK2	S408	S402F	402	Missense	distal	-6	no	12.976	12.981	EPSD	TCGA;ICGC;COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	Q53ET0	CRTC2	P24941	CDK2	S424	R429H	429	Missense	distal	5	no	14.789	14.761	EPSD	TCGA;ICGC;COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	Q53ET0	CRTC2	P24941	CDK2	S424	R428C	428	Missense	distal	4	no	14.789	14.162	EPSD	TCGA;ICGC;COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	Q53ET0	CRTC2	P24941	CDK2	S433	R429H	429	Missense	distal	-4	no	13.266	12.905	PhosphoSitePlus	TCGA;ICGC;COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	Q53ET0	CRTC2	P24941	CDK2	S433	R428C	428	Missense	distal	-5	no	13.266	13.299	PhosphoSitePlus	TCGA;ICGC;COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	Q53ET0	CRTC2	P24941	CDK2	S456	S456L	456	Missense	central	0	yes	12.882	0.000	EPSD	TCGA;ICGC;COSMIC	8.148	Loss
CMGC_CDK_CDK2_CDK2_ST	Q53ET0	CRTC2	P24941	CDK2	S460	S456L	456	Missense	distal	-4	no	14.450	14.037	EPSD	TCGA;ICGC;COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	Q53ET0	CRTC2	P24941	CDK2	S460	S464F	464	Missense	distal	4	no	14.450	14.254	EPSD	TCGA;ICGC;COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	Q53ET0	CRTC2	P24941	CDK2	S490	V494L	494	Missense	distal	4	no	12.845	12.730	EPSD	TCGA;ICGC;COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	Q53ET0	CRTC2	P24941	CDK2	S490	L495V	495	Missense	distal	5	no	12.845	12.772	EPSD	TCGA;ICGC;COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	Q53ET0	CRTC2	P24941	CDK2	T501	V494L	494	Missense	distal	-7	no	14.544	14.530	EPSD	TCGA;ICGC;COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	Q53ET0	CRTC2	P24941	CDK2	T501	L495V	495	Missense	distal	-6	no	14.544	14.545	EPSD	TCGA;ICGC;COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	Q53ET0	CRTC2	P24941	CDK2	S624	F627L	627	Missense	distal	3	no	13.549	13.207	EPSD	TCGA;ICGC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	Q53ET0	CRTC2	P24941	CDK2	S624	T620I	620	Missense	distal	-4	no	13.549	13.232	EPSD	TCGA;ICGC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	O15350	TP73	P24941	CDK2	S8	G12D	12	Missense	distal	4	no	13.666	13.721	EPSD	TCGA;ICGC;COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	O15350	TP73	P24941	CDK2	S8	A2V	2	Missense	distal	-6	no	13.666	13.669	EPSD	TCGA;ICGC;COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	O15350	TP73	P24941	CDK2	T86	S81L	81	Missense	distal	-5	no	17.190	17.246	PhosphoSitePlus	TCGA;ICGC;COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	O15350	TP73	P24941	CDK2	T86	V93M	93	Missense	distal	7	no	17.190	17.476	PhosphoSitePlus	TCGA;ICGC;COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	O15350	TP73	P24941	CDK2	T86	A79T	79	Missense	distal	-7	no	17.190	17.022	PhosphoSitePlus	TCGA;ICGC;COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	O15350	TP73	P24941	CDK2	T86	A79V	79	Missense	distal	-7	no	17.190	17.045	PhosphoSitePlus	TCGA;ICGC;COSMIC;GDSC;CCLE	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	O15350	TP73	P24941	CDK2	S145	L148F	148	Missense	distal	3	no	14.672	15.014	EPSD	TCGA;ICGC;COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	O15350	TP73	P24941	CDK2	S145	P146L	146	Missense	proximal	1	no	14.672	4.851	EPSD	TCGA;ICGC;COSMIC	8.148	Loss
CMGC_CDK_CDK2_CDK2_ST	O15350	TP73	P24941	CDK2	S145	P146S	146	Missense	proximal	1	no	14.672	3.406	EPSD	TCGA;ICGC;COSMIC	8.148	Loss
CMGC_CDK_CDK2_CDK2_ST	O15350	TP73	P24941	CDK2	S145	Y144H	144	Missense	proximal	-1	no	14.672	14.352	EPSD	TCGA;ICGC;COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	O15350	TP73	P24941	CDK2	S145	A140T	140	Missense	distal	-5	no	14.672	14.646	EPSD	TCGA;ICGC;COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	O15350	TP73	P24941	CDK2	T167	G172V	172	Missense	distal	5	no	13.388	13.228	EPSD	TCGA;ICGC;COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	O15350	TP73	P24941	CDK2	S412	G419W	419	Missense	distal	7	no	12.065	12.284	EPSD	TCGA;COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	P31943	HNRNPH1	P24941	CDK2	S269	Y266H	266	Missense	distal	-3	no	9.029	9.061	EPSD	TCGA;ICGC;COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	P31943	HNRNPH1	P24941	CDK2	S269	R275I	275	Missense	distal	6	no	9.029	9.046	EPSD	TCGA;ICGC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	P31943	HNRNPH1	P24941	CDK2	S272	Y266H	266	Missense	distal	-6	no	8.746	8.750	EPSD	TCGA;ICGC;COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	P31943	HNRNPH1	P24941	CDK2	S272	G277R	277	Missense	distal	5	no	8.746	8.726	EPSD	TCGA;ICGC;COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	P31943	HNRNPH1	P24941	CDK2	S272	R275I	275	Missense	distal	3	no	8.746	6.360	EPSD	TCGA;ICGC	8.148	Loss
CMGC_CDK_CDK2_CDK2_ST	Q99708	RBBP8	P24941	CDK2	S10	S13C	13	Missense	distal	3	no	13.152	8.473	EPSD	TCGA;ICGC;COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	Q99708	RBBP8	P24941	CDK2	S10	N12K	12	Missense	proximal	2	no	13.152	13.082	EPSD	TCGA;ICGC;COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	Q99708	RBBP8	P24941	CDK2	S10	A14V	14	Missense	distal	4	no	13.152	13.339	EPSD	TCGA;ICGC;COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	Q99708	RBBP8	P24941	CDK2	T245	P246L	246	Missense	proximal	1	no	13.967	4.146	EPSD	TCGA;ICGC;COSMIC	8.148	Loss
CMGC_CDK_CDK2_CDK2_ST	Q99708	RBBP8	P24941	CDK2	S276	M275L	275	Missense	proximal	-1	no	13.112	11.883	EPSD	TCGA;ICGC;COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	Q99708	RBBP8	P24941	CDK2	S276	P274L	274	Missense	proximal	-2	no	13.112	12.888	EPSD	TCGA;ICGC;COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	Q99708	RBBP8	P24941	CDK2	S327	A332T	332	Missense	distal	5	no	13.862	13.826	EPSD	TCGA;ICGC;COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	Q99708	RBBP8	P24941	CDK2	S347	S347F	347	Missense	central	0	yes	14.542	0.000	EPSD	TCGA;ICGC;COSMIC	8.148	Loss
CMGC_CDK_CDK2_CDK2_ST	Q99708	RBBP8	P24941	CDK2	S568	P569T	569	Missense	proximal	1	no	14.873	4.916	EPSD	TCGA;ICGC;COSMIC	8.148	Loss
CMGC_CDK_CDK2_CDK2_ST	Q99708	RBBP8	P24941	CDK2	S568	C567W	567	Missense	proximal	-1	no	14.873	16.125	EPSD	TCGA;ICGC;COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	Q99708	RBBP8	P24941	CDK2	T596	E597D	597	Missense	proximal	1	no	7.232	8.154	EPSD	TCGA;ICGC;COSMIC;GDSC;CCLE	8.148	Gain
CMGC_CDK_CDK2_CDK2_ST	Q99708	RBBP8	P24941	CDK2	T596	E597G	597	Missense	proximal	1	no	7.232	9.086	EPSD	TCGA;ICGC;COSMIC	8.148	Gain
CMGC_CDK_CDK2_CDK2_ST	Q99708	RBBP8	P24941	CDK2	T847	V854A	854	Missense	distal	7	no	15.525	15.652	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	Q99708	RBBP8	P24941	CDK2	T847	R841C	841	Missense	distal	-6	no	15.525	15.529	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	Q99708	RBBP8	P24941	CDK2	S889	K893N	893	Missense	distal	4	no	17.646	17.225	EPSD	TCGA;ICGC;COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	Q99708	RBBP8	P24941	CDK2	S889	K896T	896	Missense	distal	7	no	17.646	17.629	EPSD	TCGA;ICGC;COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	Q9NYB0	TERF2IP	P24941	CDK2	S36	F31L	31	Missense	distal	-5	no	16.320	16.259	EPSD	TCGA;ICGC;COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	Q9NYB0	TERF2IP	P24941	CDK2	T44	L45P	45	Missense	proximal	1	no	1.164	10.984	EPSD	TCGA;ICGC;COSMIC	8.148	Gain
CMGC_CDK_CDK2_CDK2_ST	Q9NYB0	TERF2IP	P24941	CDK2	S203	S206F	206	Missense	distal	3	no	14.838	14.763	PhosphoSitePlus	TCGA;ICGC;COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	Q9NYB0	TERF2IP	P24941	CDK2	T230	P225S	225	Missense	distal	-5	no	13.655	13.610	EPSD	TCGA;ICGC;COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	Q9NYB0	TERF2IP	P24941	CDK2	S269	I275K	275	Missense	distal	6	no	14.028	14.036	EPSD	TCGA;ICGC;COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	Q9NYB0	TERF2IP	P24941	CDK2	T286	C280Y	280	Missense	distal	-6	no	13.625	13.620	EPSD	TCGA;ICGC;COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	Q9NYB0	TERF2IP	P24941	CDK2	T286	D281N	281	Missense	distal	-5	no	13.625	13.587	EPSD	TCGA;ICGC;COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	P04183	TK1	P24941	CDK2	S231	A233T	233	Missense	proximal	2	no	13.098	12.896	EPSD	TCGA;COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	A1KXE4	FAM168B	P24941	CDK2	S6	V4I	4	Missense	proximal	-2	no	13.135	13.631	EPSD	TCGA;ICGC;COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	A1KXE4	FAM168B	P24941	CDK2	S6	S10P	10	Missense	distal	4	no	13.135	13.122	EPSD	TCGA;ICGC;COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	A1KXE4	FAM168B	P24941	CDK2	S6	P3S	3	Missense	distal	-3	no	13.135	13.230	EPSD	TCGA;ICGC;COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	A1KXE4	FAM168B	P24941	CDK2	S9	S10P	10	Missense	proximal	1	no	2.759	14.025	EPSD	TCGA;ICGC;COSMIC	8.148	Gain
CMGC_CDK_CDK2_CDK2_ST	A1KXE4	FAM168B	P24941	CDK2	S38	A45V	45	Missense	distal	7	no	13.468	13.342	EPSD	TCGA;ICGC;COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	A1KXE4	FAM168B	P24941	CDK2	S38	M41I	41	Missense	distal	3	no	13.468	13.040	EPSD	TCGA;ICGC;COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	A1KXE4	FAM168B	P24941	CDK2	S38	G44V	44	Missense	distal	6	no	13.468	13.478	EPSD	TCGA;ICGC;COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	A1KXE4	FAM168B	P24941	CDK2	S38	P35L	35	Missense	distal	-3	no	13.468	13.397	EPSD	TCGA;ICGC;COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	A1KXE4	FAM168B	P24941	CDK2	T57	P55A	55	Missense	proximal	-2	no	17.826	17.842	PhosphoSitePlus	TCGA;ICGC;COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	A1KXE4	FAM168B	P24941	CDK2	S166	A171T	171	Missense	distal	5	no	13.474	13.438	EPSD	TCGA;ICGC;COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	A1KXE4	FAM168B	P24941	CDK2	T168	A171T	171	Missense	distal	3	no	13.230	13.628	EPSD	TCGA;ICGC;COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	A1KXE4	FAM168B	P24941	CDK2	T185	R181Q	181	Missense	distal	-4	no	14.540	14.565	EPSD	TCGA;ICGC;COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	A1KXE4	FAM168B	P24941	CDK2	T185	Y180H	180	Missense	distal	-5	no	14.540	14.563	EPSD	TCGA;ICGC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	A1KXE4	FAM168B	P24941	CDK2	T185	Y180C	180	Missense	distal	-5	no	14.540	14.596	EPSD	TCGA;ICGC;COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	Q13330	MTA1	P24941	CDK2	S386	T380M	380	Missense	distal	-6	no	12.106	12.113	EPSD	TCGA;COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	Q13330	MTA1	P24941	CDK2	S386	G381R	381	Missense	distal	-5	no	12.106	12.073	EPSD	TCGA;COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	Q13330	MTA1	P24941	CDK2	S386	G388E	388	Missense	proximal	2	no	12.106	12.085	EPSD	TCGA;COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	Q13330	MTA1	P24941	CDK2	T399	E394D	394	Missense	distal	-5	no	8.240	8.260	EPSD	TCGA;COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	Q13330	MTA1	P24941	CDK2	T399	T398I	398	Missense	proximal	-1	no	8.240	8.486	EPSD	TCGA;COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	Q13330	MTA1	P24941	CDK2	T399	S401F	401	Missense	proximal	2	no	8.240	8.424	EPSD	TCGA;COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	Q13330	MTA1	P24941	CDK2	T399	S406Y	406	Missense	distal	7	no	8.240	8.662	EPSD	TCGA;COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	Q13330	MTA1	P24941	CDK2	S449	R445L	445	Missense	distal	-4	no	13.678	13.863	EPSD	TCGA;COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	Q13330	MTA1	P24941	CDK2	S449	R445H	445	Missense	distal	-4	no	13.678	13.317	EPSD	TCGA	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	Q13330	MTA1	P24941	CDK2	S449	N444I	444	Missense	distal	-5	no	13.678	13.698	EPSD	TCGA;COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	Q13330	MTA1	P24941	CDK2	S449	R456W	456	Missense	distal	7	no	13.678	14.078	EPSD	TCGA;COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	Q13330	MTA1	P24941	CDK2	S449	H451Q	451	Missense	proximal	2	no	13.678	13.660	EPSD	TCGA;COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	Q13330	MTA1	P24941	CDK2	S460	P461R	461	Missense	proximal	1	no	14.856	5.058	EPSD	TCGA;COSMIC	8.148	Loss
CMGC_CDK_CDK2_CDK2_ST	Q13330	MTA1	P24941	CDK2	S460	R456W	456	Missense	distal	-4	no	14.856	14.099	EPSD	TCGA;COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	Q13330	MTA1	P24941	CDK2	S460	G459R	459	Missense	proximal	-1	no	14.856	14.378	EPSD	TCGA;COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	Q13330	MTA1	P24941	CDK2	S522	S520F	520	Missense	proximal	-2	no	14.560	14.099	PhosphoSitePlus	TCGA;COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	Q13330	MTA1	P24941	CDK2	S522	E518K	518	Missense	distal	-4	no	14.560	14.249	PhosphoSitePlus	TCGA	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	Q13330	MTA1	P24941	CDK2	T564	T564M	564	Missense	central	0	yes	17.708	0.000	EPSD	TCGA;COSMIC	8.148	Loss
CMGC_CDK_CDK2_CDK2_ST	Q13330	MTA1	P24941	CDK2	T564	V571I	571	Missense	distal	7	no	17.708	17.506	EPSD	TCGA;ICGC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	Q13330	MTA1	P24941	CDK2	S576	V571I	571	Missense	distal	-5	no	13.103	13.111	EPSD	TCGA;ICGC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	Q96E09	FAM122A	P24941	CDK2	S76	H69R	69	Missense	distal	-7	no	15.061	15.282	EPSD	TCGA;ICGC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	Q96E09	FAM122A	P24941	CDK2	S133	E129D	129	Missense	distal	-4	no	14.169	14.466	EPSD	TCGA;ICGC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	Q96E09	FAM122A	P24941	CDK2	S133	R136H	136	Missense	distal	3	no	14.169	13.473	EPSD	TCGA;ICGC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	Q96E09	FAM122A	P24941	CDK2	S143	R150G	150	Missense	distal	7	no	13.945	14.125	PhosphoSitePlus	TCGA;ICGC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	Q96E09	FAM122A	P24941	CDK2	S143	P141L	141	Missense	proximal	-2	no	13.945	13.721	PhosphoSitePlus	TCGA;ICGC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	Q96E09	FAM122A	P24941	CDK2	S143	R136H	136	Missense	distal	-7	no	13.945	13.724	PhosphoSitePlus	TCGA;ICGC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	Q96E09	FAM122A	P24941	CDK2	S147	R150G	150	Missense	distal	3	no	15.447	13.628	EPSD	TCGA;ICGC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	Q96E09	FAM122A	P24941	CDK2	S173	P172S	172	Missense	proximal	-1	no	13.644	13.173	EPSD	TCGA;ICGC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	Q96E09	FAM122A	P24941	CDK2	S177	P172S	172	Missense	distal	-5	no	14.333	14.289	EPSD	TCGA;ICGC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	Q96E09	FAM122A	P24941	CDK2	S189	P190H	190	Missense	proximal	1	no	13.770	7.012	EPSD	TCGA;ICGC	8.148	Loss
CMGC_CDK_CDK2_CDK2_ST	Q96E09	FAM122A	P24941	CDK2	S189	R186I	186	Missense	distal	-3	no	13.770	13.602	EPSD	TCGA;ICGC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	Q96E09	FAM122A	P24941	CDK2	S189	S189I	189	Missense	central	0	yes	13.770	0.000	EPSD	TCGA;ICGC	8.148	Loss
CMGC_CDK_CDK2_CDK2_ST	Q96E09	FAM122A	P24941	CDK2	S257	S257L	257	Missense	central	0	yes	14.665	0.000	EPSD	TCGA;ICGC	8.148	Loss
CMGC_CDK_CDK2_CDK2_ST	Q96E09	FAM122A	P24941	CDK2	S267	A272S	272	Missense	distal	5	no	16.388	16.277	EPSD	TCGA;ICGC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	Q96E09	FAM122A	P24941	CDK2	S270	A272S	272	Missense	proximal	2	no	14.960	15.002	EPSD	TCGA;ICGC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	Q96E09	FAM122A	P24941	CDK2	S270	A275T	275	Missense	distal	5	no	14.960	14.924	EPSD	TCGA;ICGC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	Q96E09	FAM122A	P24941	CDK2	S276	A272S	272	Missense	distal	-4	no	14.278	14.691	EPSD	TCGA;ICGC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	Q96E09	FAM122A	P24941	CDK2	S276	F278C	278	Missense	proximal	2	no	14.278	14.173	EPSD	TCGA;ICGC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	Q96E09	FAM122A	P24941	CDK2	S276	A275T	275	Missense	proximal	-1	no	14.278	14.285	EPSD	TCGA;ICGC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	Q6P1N0	CC2D1A	P24941	CDK2	T120	E113Q	113	Missense	distal	-7	no	15.093	14.960	EPSD	TCGA;ICGC;COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	Q6P1N0	CC2D1A	P24941	CDK2	T204	G200S	200	Missense	distal	-4	no	12.465	13.138	EPSD	TCGA;ICGC;COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	Q6P1N0	CC2D1A	P24941	CDK2	T204	A202V	202	Missense	proximal	-2	no	12.465	11.799	EPSD	TCGA;ICGC;COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	Q6P1N0	CC2D1A	P24941	CDK2	S208	A202V	202	Missense	distal	-6	no	14.363	14.366	PhosphoSitePlus	TCGA;ICGC;COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	Q6P1N0	CC2D1A	P24941	CDK2	S239	A235T	235	Missense	distal	-4	no	12.662	12.887	EPSD	TCGA;ICGC;GDSC;CCLE	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	Q6P1N0	CC2D1A	P24941	CDK2	S239	A237P	237	Missense	proximal	-2	no	12.662	12.646	EPSD	TCGA;ICGC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	Q6P1N0	CC2D1A	P24941	CDK2	S253	P256H	256	Missense	distal	3	no	14.311	15.333	EPSD	TCGA;ICGC;COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	Q6P1N0	CC2D1A	P24941	CDK2	S253	P251S	251	Missense	proximal	-2	no	14.311	13.659	EPSD	TCGA;ICGC;COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	Q6P1N0	CC2D1A	P24941	CDK2	S324	P323L	323	Missense	proximal	-1	no	13.414	13.235	EPSD	TCGA;ICGC;GDSC;CCLE	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	Q6P1N0	CC2D1A	P24941	CDK2	S324	P326L	326	Missense	proximal	2	no	13.414	13.308	EPSD	TCGA;ICGC;COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	Q6P1N0	CC2D1A	P24941	CDK2	T331	P336S	336	Missense	distal	5	no	13.394	13.294	EPSD	TCGA;ICGC;COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	Q6P1N0	CC2D1A	P24941	CDK2	T331	P326L	326	Missense	distal	-5	no	13.394	13.406	EPSD	TCGA;ICGC;COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	Q6P1N0	CC2D1A	P24941	CDK2	S455	E448K	448	Missense	distal	-7	no	12.604	12.466	EPSD	TCGA;ICGC;COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	Q6P1N0	CC2D1A	P24941	CDK2	T470	P471L	471	Missense	proximal	1	no	12.942	3.121	EPSD	TCGA;ICGC;COSMIC	8.148	Loss
CMGC_CDK_CDK2_CDK2_ST	Q6P1N0	CC2D1A	P24941	CDK2	S707	I702M	702	Missense	distal	-5	no	17.429	17.497	EPSD	TCGA;ICGC;COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	Q6P1N0	CC2D1A	P24941	CDK2	S707	P708L	708	Missense	proximal	1	no	17.429	7.608	EPSD	TCGA;ICGC;COSMIC	8.148	Loss
CMGC_CDK_CDK2_CDK2_ST	Q53H80	AKIRIN2	P24941	CDK2	S67	E65D	65	Missense	proximal	-2	no	12.138	13.118	EPSD	TCGA	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	Q53H80	AKIRIN2	P24941	CDK2	S67	S74F	74	Missense	distal	7	no	12.138	12.991	EPSD	TCGA;ICGC;COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	Q53H80	AKIRIN2	P24941	CDK2	S125	S125L	125	Missense	central	0	yes	13.914	0.000	EPSD	TCGA;ICGC;COSMIC	8.148	Loss
CMGC_CDK_CDK2_CDK2_ST	Q53H80	AKIRIN2	P24941	CDK2	S125	S121C	121	Missense	distal	-4	no	13.914	12.808	EPSD	TCGA;ICGC;COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	Q53H80	AKIRIN2	P24941	CDK2	S125	L119I	119	Missense	distal	-6	no	13.914	13.916	EPSD	TCGA;ICGC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	P54198	HIRA	P24941	CDK2	S112	E119G	119	Missense	distal	7	no	7.621	8.246	EPSD	TCGA;ICGC;COSMIC	8.148	Gain
CMGC_CDK_CDK2_CDK2_ST	P54198	HIRA	P24941	CDK2	T508	A514T	514	Missense	distal	6	no	11.841	11.853	EPSD	TCGA;ICGC;COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	P54198	HIRA	P24941	CDK2	T544	T542A	542	Missense	proximal	-2	no	12.375	12.425	EPSD	TCGA;ICGC;COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	P54198	HIRA	P24941	CDK2	T544	N540D	540	Missense	distal	-4	no	12.375	12.764	EPSD	TCGA;ICGC;COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	P54198	HIRA	P24941	CDK2	S549	T542A	542	Missense	distal	-7	no	16.587	16.754	EPSD	TCGA;ICGC;COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	P54198	HIRA	P24941	CDK2	T555	K558N	558	Missense	distal	3	no	17.342	14.072	PhosphoSitePlus	TCGA;ICGC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	P54198	HIRA	P24941	CDK2	T576	A581S	581	Missense	distal	5	no	12.717	12.606	EPSD	TCGA;ICGC;COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	P54198	HIRA	P24941	CDK2	T576	L582M	582	Missense	distal	6	no	12.717	12.697	EPSD	TCGA;ICGC;COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	P54198	HIRA	P24941	CDK2	T576	P577L	577	Missense	proximal	1	no	12.717	2.896	EPSD	TCGA;ICGC;COSMIC	8.148	Loss
CMGC_CDK_CDK2_CDK2_ST	P54198	HIRA	P24941	CDK2	T576	R572W	572	Missense	distal	-4	no	12.717	11.959	EPSD	TCGA;ICGC;COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	P54198	HIRA	P24941	CDK2	T586	A581S	581	Missense	distal	-5	no	15.477	15.408	EPSD	TCGA;ICGC;COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	P54198	HIRA	P24941	CDK2	T586	L582M	582	Missense	distal	-4	no	15.477	14.787	EPSD	TCGA;ICGC;COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	P54198	HIRA	P24941	CDK2	S614	E616Q	616	Missense	proximal	2	no	8.248	8.211	EPSD	TCGA;ICGC;COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	P54198	HIRA	P24941	CDK2	S614	S611N	611	Missense	distal	-3	no	8.248	8.174	EPSD	TCGA;ICGC;COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	P54198	HIRA	P24941	CDK2	S661	V655L	655	Missense	distal	-6	no	12.205	12.203	EPSD	TCGA;ICGC;COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	P54198	HIRA	P24941	CDK2	S661	S656F	656	Missense	distal	-5	no	12.205	12.321	EPSD	TCGA;ICGC;COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	P54198	HIRA	P24941	CDK2	S661	P662S	662	Missense	proximal	1	no	12.205	0.939	EPSD	TCGA;ICGC;COSMIC	8.148	Loss
CMGC_CDK_CDK2_CDK2_ST	P54198	HIRA	P24941	CDK2	S687	A691T	691	Missense	distal	4	no	18.403	18.645	EPSD	TCGA;ICGC;COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	P54198	HIRA	P24941	CDK2	S687	L694F	694	Missense	distal	7	no	18.403	19.074	EPSD	TCGA;ICGC;COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	P54198	HIRA	P24941	CDK2	S687	A680V	680	Missense	distal	-7	no	18.403	18.258	EPSD	TCGA;ICGC;COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	P54198	HIRA	P24941	CDK2	S687	F692L	692	Missense	distal	5	no	18.403	18.225	EPSD	TCGA;ICGC;COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	P54198	HIRA	P24941	CDK2	S769	S775F	775	Missense	distal	6	no	11.894	11.875	EPSD	TCGA;ICGC;COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	P54198	HIRA	P24941	CDK2	S769	R765H	765	Missense	distal	-4	no	11.894	11.533	EPSD	TCGA;ICGC;COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	P54198	HIRA	P24941	CDK2	S775	S778C	778	Missense	distal	3	no	14.723	10.043	EPSD	TCGA;ICGC;COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	P54198	HIRA	P24941	CDK2	S775	T779I	779	Missense	distal	4	no	14.723	14.411	EPSD	TCGA;ICGC;COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	P54198	HIRA	P24941	CDK2	S775	S775F	775	Missense	central	0	yes	14.723	0.000	EPSD	TCGA;ICGC;COSMIC	8.148	Loss
CMGC_CDK_CDK2_CDK2_ST	Q01167	FOXK2	P24941	CDK2	S170	V175I	175	Missense	distal	5	no	16.266	16.392	EPSD	TCGA;ICGC;COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	Q01167	FOXK2	P24941	CDK2	S170	A174V	174	Missense	distal	4	no	16.266	16.453	EPSD	TCGA;ICGC;COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	Q01167	FOXK2	P24941	CDK2	S170	S170Y	170	Missense	central	0	yes	16.266	0.000	EPSD	TCGA;ICGC	8.148	Loss
CMGC_CDK_CDK2_CDK2_ST	Q01167	FOXK2	P24941	CDK2	S180	V175I	175	Missense	distal	-5	no	10.223	10.231	EPSD	TCGA;ICGC;COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	Q01167	FOXK2	P24941	CDK2	S180	A174V	174	Missense	distal	-6	no	10.223	10.226	EPSD	TCGA;ICGC;COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	Q01167	FOXK2	P24941	CDK2	S195	A191G	191	Missense	distal	-4	no	14.585	14.326	EPSD	TCGA;ICGC;COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	Q01167	FOXK2	P24941	CDK2	S195	T201M	201	Missense	distal	6	no	14.585	14.558	EPSD	TCGA;ICGC;COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	Q01167	FOXK2	P24941	CDK2	S199	A206V	206	Missense	distal	7	no	13.080	12.953	EPSD	TCGA;ICGC;COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	Q01167	FOXK2	P24941	CDK2	S199	T201M	201	Missense	proximal	2	no	13.080	13.468	EPSD	TCGA;ICGC;COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	Q01167	FOXK2	P24941	CDK2	S213	A206V	206	Missense	distal	-7	no	14.683	14.538	EPSD	TCGA;ICGC;COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	Q01167	FOXK2	P24941	CDK2	S213	P214S	214	Missense	proximal	1	no	14.683	3.417	EPSD	TCGA;ICGC;COSMIC	8.148	Loss
CMGC_CDK_CDK2_CDK2_ST	Q01167	FOXK2	P24941	CDK2	S220	P214S	214	Missense	distal	-6	no	8.192	8.191	EPSD	TCGA;ICGC;COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	Q01167	FOXK2	P24941	CDK2	S220	R226Q	226	Missense	distal	6	no	8.192	8.214	EPSD	TCGA;ICGC;COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	Q01167	FOXK2	P24941	CDK2	S252	P259L	259	Missense	distal	7	no	14.392	14.423	EPSD	TCGA;ICGC;COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	Q01167	FOXK2	P24941	CDK2	S338	S338C	338	Missense	central	0	yes	8.587	0.000	EPSD	TCGA;ICGC;COSMIC	8.148	Loss
CMGC_CDK_CDK2_CDK2_ST	Q01167	FOXK2	P24941	CDK2	S338	A337D	337	Missense	proximal	-1	no	8.587	9.613	EPSD	TCGA;ICGC;COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	Q01167	FOXK2	P24941	CDK2	S338	S338F	338	Missense	central	0	yes	8.587	0.000	EPSD	TCGA;ICGC;COSMIC;GDSC;CCLE	8.148	Loss
CMGC_CDK_CDK2_CDK2_ST	Q01167	FOXK2	P24941	CDK2	T360	P364L	364	Missense	distal	4	no	9.430	9.541	EPSD	TCGA;ICGC;COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	Q01167	FOXK2	P24941	CDK2	T360	T360I	360	Missense	central	0	yes	9.430	0.000	EPSD	TCGA;ICGC;COSMIC	8.148	Loss
CMGC_CDK_CDK2_CDK2_ST	Q01167	FOXK2	P24941	CDK2	T360	P361S	361	Missense	proximal	1	no	9.430	-1.836	EPSD	TCGA;ICGC;COSMIC	8.148	Loss
CMGC_CDK_CDK2_CDK2_ST	Q01167	FOXK2	P24941	CDK2	T360	R359K	359	Missense	proximal	-1	no	9.430	8.759	EPSD	TCGA;ICGC;COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	Q01167	FOXK2	P24941	CDK2	T389	E391D	391	Missense	proximal	2	no	12.721	12.621	EPSD	TCGA;ICGC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	Q01167	FOXK2	P24941	CDK2	S398	E391D	391	Missense	distal	-7	no	15.587	15.738	EPSD	TCGA;ICGC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	Q01167	FOXK2	P24941	CDK2	T552	T548M	548	Missense	distal	-4	no	12.870	11.955	EPSD	TCGA;ICGC;COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	Q01167	FOXK2	P24941	CDK2	T552	P553L	553	Missense	proximal	1	no	12.870	3.049	EPSD	TCGA;ICGC;COSMIC	8.148	Loss
CMGC_CDK_CDK2_CDK2_ST	Q01167	FOXK2	P24941	CDK2	S599	A597S	597	Missense	proximal	-2	no	15.293	14.626	EPSD	TCGA;COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	Q01167	FOXK2	P24941	CDK2	S599	A597V	597	Missense	proximal	-2	no	15.293	14.627	EPSD	TCGA;ICGC;CCLE	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	Q01167	FOXK2	P24941	CDK2	T648	V641I	641	Missense	distal	-7	no	15.161	15.336	EPSD	TCGA;ICGC;COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	P30307	CDC25C	P24941	CDK2	T67	D73N	73	Missense	distal	6	no	15.210	15.229	EPSD	TCGA;ICGC;COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	P30307	CDC25C	P24941	CDK2	S122	L127I	127	Missense	distal	5	no	14.438	14.491	EPSD	TCGA;ICGC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	P30307	CDC25C	P24941	CDK2	S122	L127V	127	Missense	distal	5	no	14.438	14.365	EPSD	TCGA;ICGC;COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	P30307	CDC25C	P24941	CDK2	T130	G137C	137	Missense	distal	7	no	10.654	10.624	EPSD	TCGA;ICGC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	P30307	CDC25C	P24941	CDK2	T130	L127I	127	Missense	distal	-3	no	10.654	10.744	EPSD	TCGA;ICGC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	P30307	CDC25C	P24941	CDK2	T130	L127V	127	Missense	distal	-3	no	10.654	10.867	EPSD	TCGA;ICGC;COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	P30307	CDC25C	P24941	CDK2	S214	P215Q	215	Missense	proximal	1	no	13.103	5.192	PhosphoSitePlus	TCGA;ICGC;COSMIC	8.148	Loss
CMGC_CDK_CDK2_CDK2_ST	P30307	CDC25C	P24941	CDK2	S214	R213H	213	Missense	proximal	-1	no	13.103	12.652	PhosphoSitePlus	TCGA;ICGC;COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	P30307	CDC25C	P24941	CDK2	S214	R213C	213	Missense	proximal	-1	no	13.103	12.406	PhosphoSitePlus	TCGA;ICGC;COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	P30307	CDC25C	P24941	CDK2	S214	S214F	214	Missense	central	0	yes	13.103	0.000	PhosphoSitePlus	TCGA;ICGC;COSMIC	8.148	Loss
CMGC_CDK_CDK2_CDK2_ST	P30307	CDC25C	P24941	CDK2	S214	L221S	221	Missense	distal	7	no	13.103	12.921	PhosphoSitePlus	TCGA;ICGC;COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	P30307	CDC25C	P24941	CDK2	S214	P218S	218	Missense	distal	4	no	13.103	13.117	PhosphoSitePlus	TCGA;ICGC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	Q9Y2K7	KDM2A	P24941	CDK2	S394	S390F	390	Missense	distal	-4	no	14.691	13.729	EPSD	TCGA;ICGC;COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	Q9Y2K7	KDM2A	P24941	CDK2	S562	R566W	566	Missense	distal	4	no	8.245	7.885	EPSD	TCGA;ICGC;COSMIC	8.148	Loss
CMGC_CDK_CDK2_CDK2_ST	Q9Y2K7	KDM2A	P24941	CDK2	T713	T713M	713	Missense	central	0	yes	15.120	0.000	EPSD	TCGA;ICGC;COSMIC;GDSC	8.148	Loss
CMGC_CDK_CDK2_CDK2_ST	Q9Y2K7	KDM2A	P24941	CDK2	S718	T713M	713	Missense	distal	-5	no	10.154	10.262	EPSD	TCGA;ICGC;COSMIC;GDSC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	Q9Y2K7	KDM2A	P24941	CDK2	S731	R738Q	738	Missense	distal	7	no	12.131	11.487	EPSD	TCGA;ICGC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	Q9Y2K7	KDM2A	P24941	CDK2	S740	S746R	746	Missense	distal	6	no	13.188	13.170	EPSD	TCGA;ICGC;COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	Q9Y2K7	KDM2A	P24941	CDK2	S740	R738Q	738	Missense	proximal	-2	no	13.188	13.856	EPSD	TCGA;ICGC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	Q9Y2K7	KDM2A	P24941	CDK2	S781	R774W	774	Missense	distal	-7	no	8.153	8.324	EPSD	TCGA;COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	Q9Y2K7	KDM2A	P24941	CDK2	S826	A827P	827	Missense	proximal	1	no	-0.322	14.081	EPSD	TCGA;COSMIC	8.148	Gain
CMGC_CDK_CDK2_CDK2_ST	Q9Y2K7	KDM2A	P24941	CDK2	S832	A827P	827	Missense	distal	-5	no	14.498	14.473	EPSD	TCGA;COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	Q9Y2K7	KDM2A	P24941	CDK2	S832	R830H	830	Missense	proximal	-2	no	14.498	14.724	EPSD	TCGA;ICGC;COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	Q9Y2K7	KDM2A	P24941	CDK2	T844	A842V	842	Missense	proximal	-2	no	14.667	14.001	EPSD	TCGA;ICGC;COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	Q9Y2K7	KDM2A	P24941	CDK2	T1024	R1020W	1020	Missense	distal	-4	no	14.432	13.675	EPSD	TCGA;COSMIC;GDSC;CCLE	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	Q9Y2K7	KDM2A	P24941	CDK2	T1024	A1027P	1027	Missense	distal	3	no	14.432	14.944	EPSD	TCGA;COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	Q9Y2K7	KDM2A	P24941	CDK2	T1024	P1017S	1017	Missense	distal	-7	no	14.432	14.252	EPSD	TCGA;COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	Q14207	NPAT	P24941	CDK2	S102	Q95H	95	Missense	distal	-7	no	12.263	12.429	EPSD	TCGA;ICGC;COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	Q14207	NPAT	P24941	CDK2	S102	G107D	107	Missense	distal	5	no	12.263	12.311	EPSD	TCGA;ICGC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	Q14207	NPAT	P24941	CDK2	S102	M99T	99	Missense	distal	-3	no	12.263	11.856	EPSD	TCGA;ICGC;COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	Q14207	NPAT	P24941	CDK2	T149	L143F	143	Missense	distal	-6	no	11.660	11.664	EPSD	TCGA;ICGC;COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	Q14207	NPAT	P24941	CDK2	S207	S213N	213	Missense	distal	6	no	16.393	16.396	EPSD	TCGA;COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	Q14207	NPAT	P24941	CDK2	S207	S207Y	207	Missense	central	0	yes	16.393	0.000	EPSD	TCGA;ICGC;COSMIC	8.148	Loss
CMGC_CDK_CDK2_CDK2_ST	Q14207	NPAT	P24941	CDK2	S207	R211C	211	Missense	distal	4	no	16.393	15.766	EPSD	TCGA;ICGC;COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	Q14207	NPAT	P24941	CDK2	S535	S539L	539	Missense	distal	4	no	8.532	8.630	EPSD	TCGA;ICGC;COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	Q14207	NPAT	P24941	CDK2	S535	L540I	540	Missense	distal	5	no	8.532	8.584	EPSD	TCGA;ICGC;COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	Q14207	NPAT	P24941	CDK2	T688	T688M	688	Missense	central	0	yes	13.285	0.000	EPSD	TCGA;ICGC;COSMIC	8.148	Loss
CMGC_CDK_CDK2_CDK2_ST	Q14207	NPAT	P24941	CDK2	T693	E696K	696	Missense	distal	3	no	13.038	15.124	EPSD	TCGA;ICGC;COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	Q14207	NPAT	P24941	CDK2	T693	T688M	688	Missense	distal	-5	no	13.038	13.146	EPSD	TCGA;ICGC;COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	Q14207	NPAT	P24941	CDK2	S775	P776A	776	Missense	proximal	1	no	13.624	-0.780	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	8.148	Loss
CMGC_CDK_CDK2_CDK2_ST	Q14207	NPAT	P24941	CDK2	S775	S775F	775	Missense	central	0	yes	13.624	0.000	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	8.148	Loss
CMGC_CDK_CDK2_CDK2_ST	Q14207	NPAT	P24941	CDK2	S775	K782E	782	Missense	distal	7	no	13.624	13.954	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	Q14207	NPAT	P24941	CDK2	S779	P776A	776	Missense	distal	-3	no	17.533	17.474	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	Q14207	NPAT	P24941	CDK2	S779	S775F	775	Missense	distal	-4	no	17.533	16.571	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	Q14207	NPAT	P24941	CDK2	S779	K782E	782	Missense	distal	3	no	17.533	15.447	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	Q14207	NPAT	P24941	CDK2	T908	N913S	913	Missense	distal	5	no	12.485	12.281	EPSD	TCGA;ICGC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	Q14207	NPAT	P24941	CDK2	T908	P901L	901	Missense	distal	-7	no	12.485	12.491	EPSD	TCGA;ICGC;COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	Q14207	NPAT	P24941	CDK2	T963	V968I	968	Missense	distal	5	no	13.682	13.807	EPSD	TCGA;ICGC;COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	Q14207	NPAT	P24941	CDK2	T963	Q956H	956	Missense	distal	-7	no	13.682	13.848	EPSD	TCGA;ICGC;COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	Q14207	NPAT	P24941	CDK2	S1100	L1098P	1098	Missense	proximal	-2	no	14.290	14.514	PhosphoSitePlus;EPSD	TCGA;ICGC;COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	Q14207	NPAT	P24941	CDK2	S1100	D1099V	1099	Missense	proximal	-1	no	14.290	13.491	PhosphoSitePlus;EPSD	TCGA;ICGC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	Q14207	NPAT	P24941	CDK2	S1100	L1098I	1098	Missense	proximal	-2	no	14.290	14.360	PhosphoSitePlus;EPSD	TCGA;ICGC;COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	Q14207	NPAT	P24941	CDK2	S1151	S1146L	1146	Missense	distal	-5	no	13.428	13.484	EPSD	TCGA;ICGC;COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	Q14207	NPAT	P24941	CDK2	S1151	E1158Q	1158	Missense	distal	7	no	13.428	13.229	EPSD	TCGA;ICGC;COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	Q14207	NPAT	P24941	CDK2	S1151	K1148N	1148	Missense	distal	-3	no	13.428	13.490	EPSD	TCGA;ICGC;COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	Q14207	NPAT	P24941	CDK2	T1270	R1269W	1269	Missense	proximal	-1	no	16.167	16.721	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	Q01196	RUNX1	P24941	CDK2	S212	P216H	216	Missense	distal	4	no	14.217	13.979	EPSD	TCGA	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	Q01196	RUNX1	P24941	CDK2	T219	P216H	216	Missense	distal	-3	no	12.637	12.783	EPSD	TCGA	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	Q01196	RUNX1	P24941	CDK2	S304	P298Q	298	Missense	distal	-6	no	11.112	11.115	EPSD	TCGA;ICGC;COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	Q01196	RUNX1	P24941	CDK2	S435	A440T	440	Missense	distal	5	no	14.732	14.696	EPSD	TCGA;ICGC;COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	P48200	IREB2	P24941	CDK2	S157	K160E	160	Missense	distal	3	no	18.378	16.292	PhosphoSitePlus	TCGA;ICGC;COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	P48200	IREB2	P24941	CDK2	S495	H491Y	491	Missense	distal	-4	no	8.033	9.103	EPSD	TCGA;ICGC;COSMIC	8.148	Gain
CMGC_CDK_CDK2_CDK2_ST	P48200	IREB2	P24941	CDK2	T777	R779H	779	Missense	proximal	2	no	14.247	14.166	EPSD	TCGA;ICGC;COSMIC;CCLE	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	P30050	RPL12	P24941	CDK2	S157	A159V	159	Missense	proximal	2	no	9.198	9.295	EPSD	TCGA;ICGC;COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	P30050	RPL12	P24941	CDK2	S157	D153N	153	Missense	distal	-4	no	9.198	8.809	EPSD	TCGA;COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	Q9NYF8	BCLAF1	P24941	CDK2	S44	R51C	51	Missense	distal	7	no	8.178	8.329	EPSD	TCGA;ICGC;COSMIC;GDSC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	Q9NYF8	BCLAF1	P24941	CDK2	S44	R51H	51	Missense	distal	7	no	8.178	7.820	EPSD	TCGA;ICGC;COSMIC	8.148	Loss
CMGC_CDK_CDK2_CDK2_ST	Q9NYF8	BCLAF1	P24941	CDK2	S46	R51C	51	Missense	distal	5	no	8.094	8.222	EPSD	TCGA;ICGC;COSMIC;GDSC	8.148	Gain
CMGC_CDK_CDK2_CDK2_ST	Q9NYF8	BCLAF1	P24941	CDK2	S104	S102C	102	Missense	proximal	-2	no	16.166	15.756	EPSD	TCGA;ICGC;COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	Q9NYF8	BCLAF1	P24941	CDK2	S104	S104C	104	Missense	central	0	yes	16.166	0.000	EPSD	TCGA	8.148	Loss
CMGC_CDK_CDK2_CDK2_ST	Q9NYF8	BCLAF1	P24941	CDK2	S104	R103G	103	Missense	proximal	-1	no	16.166	16.644	EPSD	TCGA;ICGC;COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	Q9NYF8	BCLAF1	P24941	CDK2	S104	R109S	109	Missense	distal	5	no	16.166	15.959	EPSD	TCGA;ICGC;COSMIC;GDSC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	Q9NYF8	BCLAF1	P24941	CDK2	S104	R103S	103	Missense	proximal	-1	no	16.166	15.125	EPSD	TCGA;ICGC;COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	Q9NYF8	BCLAF1	P24941	CDK2	S104	R99G	99	Missense	distal	-5	no	16.166	16.199	EPSD	TCGA;COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	Q9NYF8	BCLAF1	P24941	CDK2	S104	R109L	109	Missense	distal	5	no	16.166	16.100	EPSD	TCGA;ICGC;COSMIC;GDSC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	Q9NYF8	BCLAF1	P24941	CDK2	S104	R109C	109	Missense	distal	5	no	16.166	16.294	EPSD	TCGA;ICGC;COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	Q9NYF8	BCLAF1	P24941	CDK2	S104	R111H	111	Missense	distal	7	no	16.166	15.808	EPSD	TCGA;COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	Q9NYF8	BCLAF1	P24941	CDK2	S104	R99K	99	Missense	distal	-5	no	16.166	16.122	EPSD	TCGA;COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	Q9NYF8	BCLAF1	P24941	CDK2	S114	V120F	120	Missense	distal	6	no	14.129	14.113	EPSD	TCGA;COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	Q9NYF8	BCLAF1	P24941	CDK2	S114	R118I	118	Missense	distal	4	no	14.129	14.221	EPSD	TCGA;COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	Q9NYF8	BCLAF1	P24941	CDK2	S114	R118K	118	Missense	distal	4	no	14.129	14.651	EPSD	TCGA;ICGC;COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	Q9NYF8	BCLAF1	P24941	CDK2	S114	R109S	109	Missense	distal	-5	no	14.129	14.038	EPSD	TCGA;ICGC;COSMIC;GDSC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	Q9NYF8	BCLAF1	P24941	CDK2	S114	R109L	109	Missense	distal	-5	no	14.129	14.094	EPSD	TCGA;ICGC;COSMIC;GDSC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	Q9NYF8	BCLAF1	P24941	CDK2	S114	S110L	110	Missense	distal	-4	no	14.129	13.716	EPSD	TCGA;COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	Q9NYF8	BCLAF1	P24941	CDK2	S114	R109C	109	Missense	distal	-5	no	14.129	14.163	EPSD	TCGA;ICGC;COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	Q9NYF8	BCLAF1	P24941	CDK2	S114	R117K	117	Missense	distal	3	no	14.129	15.118	EPSD	TCGA;ICGC;COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	Q9NYF8	BCLAF1	P24941	CDK2	S114	V120L	120	Missense	distal	6	no	14.129	14.132	EPSD	TCGA;COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	Q9NYF8	BCLAF1	P24941	CDK2	S114	R111H	111	Missense	distal	-3	no	14.129	14.087	EPSD	TCGA;COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	Q9NYF8	BCLAF1	P24941	CDK2	S138	R131Q	131	Missense	distal	-7	no	16.318	15.932	EPSD	TCGA;ICGC;COSMIC;GDSC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	Q9NYF8	BCLAF1	P24941	CDK2	S138	R137M	137	Missense	proximal	-1	no	16.318	16.797	EPSD	TCGA;ICGC;COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	Q9NYF8	BCLAF1	P24941	CDK2	S138	R131P	131	Missense	distal	-7	no	16.318	15.975	EPSD	TCGA;ICGC;COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	Q9NYF8	BCLAF1	P24941	CDK2	S138	R131L	131	Missense	distal	-7	no	16.318	15.980	EPSD	TCGA;COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	Q9NYF8	BCLAF1	P24941	CDK2	S138	S141L	141	Missense	distal	3	no	16.318	15.901	EPSD	TCGA;ICGC;COSMIC;GDSC;CCLE	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	Q9NYF8	BCLAF1	P24941	CDK2	S138	R145C	145	Missense	distal	7	no	16.318	16.469	EPSD	TCGA;COSMIC;CCLE	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	Q9NYF8	BCLAF1	P24941	CDK2	S138	S144A	144	Missense	distal	6	no	16.318	16.313	EPSD	TCGA;COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	Q9NYF8	BCLAF1	P24941	CDK2	S138	R134I	134	Missense	distal	-4	no	16.318	16.410	EPSD	TCGA;ICGC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	Q9NYF8	BCLAF1	P24941	CDK2	S138	S136C	136	Missense	proximal	-2	no	16.318	15.908	EPSD	TCGA;COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	Q9NYF8	BCLAF1	P24941	CDK2	S148	S148Y	148	Missense	central	0	yes	14.186	0.000	EPSD	TCGA;COSMIC	8.148	Loss
CMGC_CDK_CDK2_CDK2_ST	Q9NYF8	BCLAF1	P24941	CDK2	S148	S147L	147	Missense	proximal	-1	no	14.186	14.478	EPSD	TCGA;ICGC;COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	Q9NYF8	BCLAF1	P24941	CDK2	S148	Y150H	150	Missense	proximal	2	no	14.186	14.206	EPSD	TCGA;ICGC;COSMIC;GDSC;CCLE	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	Q9NYF8	BCLAF1	P24941	CDK2	S148	S141L	141	Missense	distal	-7	no	14.186	14.372	EPSD	TCGA;ICGC;COSMIC;GDSC;CCLE	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	Q9NYF8	BCLAF1	P24941	CDK2	S148	R145C	145	Missense	distal	-3	no	14.186	14.101	EPSD	TCGA;COSMIC;CCLE	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	Q9NYF8	BCLAF1	P24941	CDK2	S148	K152R	152	Missense	distal	4	no	14.186	13.665	EPSD	TCGA;ICGC;COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	Q9NYF8	BCLAF1	P24941	CDK2	S148	S144A	144	Missense	distal	-4	no	14.186	13.773	EPSD	TCGA;COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	Q9NYF8	BCLAF1	P24941	CDK2	S148	P154L	154	Missense	distal	6	no	14.186	14.188	EPSD	TCGA;ICGC;COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	Q9NYF8	BCLAF1	P24941	CDK2	S148	P149L	149	Missense	proximal	1	no	14.186	4.365	EPSD	TCGA;ICGC;COSMIC	8.148	Loss
CMGC_CDK_CDK2_CDK2_ST	Q9NYF8	BCLAF1	P24941	CDK2	S148	S151N	151	Missense	distal	3	no	14.186	13.590	EPSD	TCGA	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	Q9NYF8	BCLAF1	P24941	CDK2	S153	S148Y	148	Missense	distal	-5	no	12.146	12.214	EPSD	TCGA;COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	Q9NYF8	BCLAF1	P24941	CDK2	S153	S147L	147	Missense	distal	-6	no	12.146	12.147	EPSD	TCGA;ICGC;COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	Q9NYF8	BCLAF1	P24941	CDK2	S153	Y150H	150	Missense	distal	-3	no	12.146	12.177	EPSD	TCGA;ICGC;COSMIC;GDSC;CCLE	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	Q9NYF8	BCLAF1	P24941	CDK2	S153	G160W	160	Missense	distal	7	no	12.146	12.365	EPSD	TCGA;ICGC;COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	Q9NYF8	BCLAF1	P24941	CDK2	S153	K152R	152	Missense	proximal	-1	no	12.146	12.817	EPSD	TCGA;ICGC;COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	Q9NYF8	BCLAF1	P24941	CDK2	S153	R159Q	159	Missense	distal	6	no	12.146	12.168	EPSD	TCGA;ICGC;COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	Q9NYF8	BCLAF1	P24941	CDK2	S153	P154L	154	Missense	proximal	1	no	12.146	2.325	EPSD	TCGA;ICGC;COSMIC	8.148	Loss
CMGC_CDK_CDK2_CDK2_ST	Q9NYF8	BCLAF1	P24941	CDK2	S153	P149L	149	Missense	distal	-4	no	12.146	12.088	EPSD	TCGA;ICGC;COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	Q9NYF8	BCLAF1	P24941	CDK2	S153	S151N	151	Missense	proximal	-2	no	12.146	11.454	EPSD	TCGA	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	Q9NYF8	BCLAF1	P24941	CDK2	S153	R158K	158	Missense	distal	5	no	12.146	11.985	EPSD	TCGA;COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	Q9NYF8	BCLAF1	P24941	CDK2	S177	P173L	173	Missense	distal	-4	no	14.882	14.824	EPSD	TCGA;ICGC;COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	Q9NYF8	BCLAF1	P24941	CDK2	S177	Q184L	184	Missense	distal	7	no	14.882	15.067	EPSD	TCGA;COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	Q9NYF8	BCLAF1	P24941	CDK2	S177	E170K	170	Missense	distal	-7	no	14.882	14.745	EPSD	TCGA;COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	Q9NYF8	BCLAF1	P24941	CDK2	S177	E170G	170	Missense	distal	-7	no	14.882	15.116	EPSD	TCGA;COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	Q9NYF8	BCLAF1	P24941	CDK2	S222	P229S	229	Missense	distal	7	no	14.360	14.208	EPSD	TCGA;COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	Q9NYF8	BCLAF1	P24941	CDK2	S222	R224I	224	Missense	proximal	2	no	14.360	14.179	EPSD	TCGA;ICGC;COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	Q9NYF8	BCLAF1	P24941	CDK2	S222	S228I	228	Missense	distal	6	no	14.360	14.359	EPSD	TCGA;COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	Q9NYF8	BCLAF1	P24941	CDK2	S222	S225L	225	Missense	distal	3	no	14.360	13.943	EPSD	TCGA;ICGC;COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	Q9NYF8	BCLAF1	P24941	CDK2	S222	N221D	221	Missense	proximal	-1	no	14.360	15.190	EPSD	TCGA;ICGC;COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	Q9NYF8	BCLAF1	P24941	CDK2	S222	N221I	221	Missense	proximal	-1	no	14.360	14.417	EPSD	TCGA;ICGC;COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	Q9NYF8	BCLAF1	P24941	CDK2	S222	G215C	215	Missense	distal	-7	no	14.360	14.307	EPSD	TCGA;COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	Q9NYF8	BCLAF1	P24941	CDK2	S225	P229S	229	Missense	distal	4	no	14.937	14.950	EPSD	TCGA;COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	Q9NYF8	BCLAF1	P24941	CDK2	S225	S230L	230	Missense	distal	5	no	14.937	15.078	EPSD	TCGA;ICGC;COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	Q9NYF8	BCLAF1	P24941	CDK2	S225	R224I	224	Missense	proximal	-1	no	14.937	14.349	EPSD	TCGA;ICGC;COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	Q9NYF8	BCLAF1	P24941	CDK2	S225	S228I	228	Missense	distal	3	no	14.937	14.235	EPSD	TCGA;COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	Q9NYF8	BCLAF1	P24941	CDK2	S225	S225L	225	Missense	central	0	yes	14.937	0.000	EPSD	TCGA;ICGC;COSMIC	8.148	Loss
CMGC_CDK_CDK2_CDK2_ST	Q9NYF8	BCLAF1	P24941	CDK2	S225	N221D	221	Missense	distal	-4	no	14.937	15.325	EPSD	TCGA;ICGC;COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	Q9NYF8	BCLAF1	P24941	CDK2	S225	N221I	221	Missense	distal	-4	no	14.937	14.648	EPSD	TCGA;ICGC;COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	Q9NYF8	BCLAF1	P24941	CDK2	S228	P229S	229	Missense	proximal	1	no	12.823	1.557	EPSD	TCGA;COSMIC	8.148	Loss
CMGC_CDK_CDK2_CDK2_ST	Q9NYF8	BCLAF1	P24941	CDK2	S228	S230L	230	Missense	proximal	2	no	12.823	12.649	EPSD	TCGA;ICGC;COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	Q9NYF8	BCLAF1	P24941	CDK2	S228	R224I	224	Missense	distal	-4	no	12.823	12.915	EPSD	TCGA;ICGC;COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	Q9NYF8	BCLAF1	P24941	CDK2	S228	S228I	228	Missense	central	0	yes	12.823	0.000	EPSD	TCGA;COSMIC	8.148	Loss
CMGC_CDK_CDK2_CDK2_ST	Q9NYF8	BCLAF1	P24941	CDK2	S228	S225L	225	Missense	distal	-3	no	12.823	12.656	EPSD	TCGA;ICGC;COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	Q9NYF8	BCLAF1	P24941	CDK2	S228	N221D	221	Missense	distal	-7	no	12.823	13.145	EPSD	TCGA;ICGC;COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	Q9NYF8	BCLAF1	P24941	CDK2	S228	P235L	235	Missense	distal	7	no	12.823	12.853	EPSD	TCGA;ICGC;COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	Q9NYF8	BCLAF1	P24941	CDK2	S228	N221I	221	Missense	distal	-7	no	12.823	13.098	EPSD	TCGA;ICGC;COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	Q9NYF8	BCLAF1	P24941	CDK2	S230	P229S	229	Missense	proximal	-1	no	11.833	11.362	EPSD	TCGA;COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	Q9NYF8	BCLAF1	P24941	CDK2	S230	S230L	230	Missense	central	0	yes	11.833	0.000	EPSD	TCGA;ICGC;COSMIC	8.148	Loss
CMGC_CDK_CDK2_CDK2_ST	Q9NYF8	BCLAF1	P24941	CDK2	S230	P236L	236	Missense	distal	6	no	11.833	11.835	EPSD	TCGA;COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	Q9NYF8	BCLAF1	P24941	CDK2	S230	P236H	236	Missense	distal	6	no	11.833	11.828	EPSD	TCGA;ICGC;COSMIC;GDSC;CCLE	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	Q9NYF8	BCLAF1	P24941	CDK2	S230	P236T	236	Missense	distal	6	no	11.833	11.841	EPSD	TCGA;COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	Q9NYF8	BCLAF1	P24941	CDK2	S230	S228I	228	Missense	proximal	-2	no	11.833	12.330	EPSD	TCGA;COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	Q9NYF8	BCLAF1	P24941	CDK2	S230	S225L	225	Missense	distal	-5	no	11.833	11.889	EPSD	TCGA;ICGC;COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	Q9NYF8	BCLAF1	P24941	CDK2	S230	S237R	237	Missense	distal	7	no	11.833	12.475	EPSD	TCGA;COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	Q9NYF8	BCLAF1	P24941	CDK2	S230	P235L	235	Missense	distal	5	no	11.833	11.873	EPSD	TCGA;ICGC;COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	Q9NYF8	BCLAF1	P24941	CDK2	T234	P229S	229	Missense	distal	-5	no	13.445	13.400	EPSD	TCGA;COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	Q9NYF8	BCLAF1	P24941	CDK2	T234	S230L	230	Missense	distal	-4	no	13.445	13.032	EPSD	TCGA;ICGC;COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	Q9NYF8	BCLAF1	P24941	CDK2	T234	P236L	236	Missense	proximal	2	no	13.445	13.338	EPSD	TCGA;COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	Q9NYF8	BCLAF1	P24941	CDK2	T234	P236H	236	Missense	proximal	2	no	13.445	13.522	EPSD	TCGA;ICGC;COSMIC;GDSC;CCLE	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	Q9NYF8	BCLAF1	P24941	CDK2	T234	P236T	236	Missense	proximal	2	no	13.445	13.267	EPSD	TCGA;COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	Q9NYF8	BCLAF1	P24941	CDK2	T234	S228I	228	Missense	distal	-6	no	13.445	13.448	EPSD	TCGA;COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	Q9NYF8	BCLAF1	P24941	CDK2	T234	S240P	240	Missense	distal	6	no	13.445	13.443	EPSD	TCGA;ICGC;COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	Q9NYF8	BCLAF1	P24941	CDK2	T234	S237R	237	Missense	distal	3	no	13.445	15.129	EPSD	TCGA;COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	Q9NYF8	BCLAF1	P24941	CDK2	T234	P235L	235	Missense	proximal	1	no	13.445	3.624	EPSD	TCGA;ICGC;COSMIC	8.148	Loss
CMGC_CDK_CDK2_CDK2_ST	Q9NYF8	BCLAF1	P24941	CDK2	S239	S240P	240	Missense	proximal	1	no	-2.670	8.596	EPSD	TCGA;ICGC;COSMIC	8.148	Gain
CMGC_CDK_CDK2_CDK2_ST	Q9NYF8	BCLAF1	P24941	CDK2	T257	Q260E	260	Missense	distal	3	no	11.189	11.835	EPSD	TCGA;COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	Q9NYF8	BCLAF1	P24941	CDK2	T257	T250I	250	Missense	distal	-7	no	11.189	11.386	EPSD	TCGA;ICGC;COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	Q9NYF8	BCLAF1	P24941	CDK2	T257	H263L	263	Missense	distal	6	no	11.189	11.195	EPSD	TCGA;ICGC;COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	Q9NYF8	BCLAF1	P24941	CDK2	T257	H252P	252	Missense	distal	-5	no	11.189	11.142	EPSD	TCGA;COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	Q9NYF8	BCLAF1	P24941	CDK2	T257	H252Q	252	Missense	distal	-5	no	11.189	11.142	EPSD	TCGA;ICGC;COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	Q9NYF8	BCLAF1	P24941	CDK2	T257	Q260L	260	Missense	distal	3	no	11.189	10.830	EPSD	TCGA;COSMIC;GDSC;CCLE	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	Q9NYF8	BCLAF1	P24941	CDK2	T257	S259F	259	Missense	proximal	2	no	11.189	11.373	EPSD	TCGA;COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	Q9NYF8	BCLAF1	P24941	CDK2	T257	H252Y	252	Missense	distal	-5	no	11.189	11.166	EPSD	TCGA;ICGC;COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	Q9NYF8	BCLAF1	P24941	CDK2	T257	S264F	264	Missense	distal	7	no	11.189	12.042	EPSD	TCGA;COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	Q9NYF8	BCLAF1	P24941	CDK2	S262	Q260L	260	Missense	proximal	-2	no	8.030	8.373	EPSD	TCGA;COSMIC;GDSC;CCLE	8.148	Gain
CMGC_CDK_CDK2_CDK2_ST	Q9NYF8	BCLAF1	P24941	CDK2	S262	S264F	264	Missense	proximal	2	no	8.030	8.215	EPSD	TCGA;COSMIC	8.148	Gain
CMGC_CDK_CDK2_CDK2_ST	Q9NYF8	BCLAF1	P24941	CDK2	S268	H263L	263	Missense	distal	-5	no	15.574	15.539	EPSD	TCGA;ICGC;COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	Q9NYF8	BCLAF1	P24941	CDK2	S268	S264F	264	Missense	distal	-4	no	15.574	14.612	EPSD	TCGA;COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	Q9NYF8	BCLAF1	P24941	CDK2	S268	E270K	270	Missense	proximal	2	no	15.574	15.337	EPSD	TCGA;COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	Q9NYF8	BCLAF1	P24941	CDK2	S285	Y284C	284	Missense	proximal	-1	no	14.602	14.036	EPSD	TCGA;ICGC;COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	Q9NYF8	BCLAF1	P24941	CDK2	S285	N279I	279	Missense	distal	-6	no	14.602	14.605	EPSD	TCGA;ICGC;COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	Q9NYF8	BCLAF1	P24941	CDK2	S285	R283Q	283	Missense	proximal	-2	no	14.602	15.271	EPSD	TCGA;ICGC;COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	Q9NYF8	BCLAF1	P24941	CDK2	S290	Y284C	284	Missense	distal	-6	no	13.271	13.276	EPSD	TCGA;ICGC;COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	Q9NYF8	BCLAF1	P24941	CDK2	S290	I295N	295	Missense	distal	5	no	13.271	13.281	EPSD	TCGA;COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	Q9NYF8	BCLAF1	P24941	CDK2	S290	R283Q	283	Missense	distal	-7	no	13.271	12.884	EPSD	TCGA;ICGC;COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	Q9NYF8	BCLAF1	P24941	CDK2	S290	S297P	297	Missense	distal	7	no	13.271	13.423	EPSD	TCGA;ICGC;COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	Q9NYF8	BCLAF1	P24941	CDK2	S290	H293N	293	Missense	distal	3	no	13.271	11.686	EPSD	TCGA;ICGC;COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	Q9NYF8	BCLAF1	P24941	CDK2	S300	A306T	306	Missense	distal	6	no	17.632	17.644	EPSD	TCGA;ICGC;COSMIC;GDSC;CCLE	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	Q9NYF8	BCLAF1	P24941	CDK2	S300	A302S	302	Missense	proximal	2	no	17.632	17.674	EPSD	TCGA;ICGC;COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	Q9NYF8	BCLAF1	P24941	CDK2	S300	I295N	295	Missense	distal	-5	no	17.632	17.612	EPSD	TCGA;COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	Q9NYF8	BCLAF1	P24941	CDK2	S300	P307S	307	Missense	distal	7	no	17.632	17.480	EPSD	TCGA;ICGC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	Q9NYF8	BCLAF1	P24941	CDK2	S300	P307L	307	Missense	distal	7	no	17.632	17.662	EPSD	TCGA;ICGC;COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	Q9NYF8	BCLAF1	P24941	CDK2	S300	P301L	301	Missense	proximal	1	no	17.632	7.811	EPSD	TCGA;COSMIC	8.148	Loss
CMGC_CDK_CDK2_CDK2_ST	Q9NYF8	BCLAF1	P24941	CDK2	S300	S297P	297	Missense	distal	-3	no	17.632	17.537	EPSD	TCGA;ICGC;COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	Q9NYF8	BCLAF1	P24941	CDK2	S300	H293N	293	Missense	distal	-7	no	17.632	17.427	EPSD	TCGA;ICGC;COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	Q9NYF8	BCLAF1	P24941	CDK2	S319	S320P	320	Missense	proximal	1	no	4.593	15.859	EPSD	TCGA;COSMIC	8.148	Gain
CMGC_CDK_CDK2_CDK2_ST	Q9NYF8	BCLAF1	P24941	CDK2	S385	Y383H	383	Missense	proximal	-2	no	8.344	7.898	EPSD	TCGA	8.148	Loss
CMGC_CDK_CDK2_CDK2_ST	Q9NYF8	BCLAF1	P24941	CDK2	S385	K387R	387	Missense	proximal	2	no	8.344	8.644	EPSD	TCGA;COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	Q9NYF8	BCLAF1	P24941	CDK2	S385	G390E	390	Missense	distal	5	no	8.344	8.296	EPSD	TCGA;COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	Q9NYF8	BCLAF1	P24941	CDK2	S385	D386N	386	Missense	proximal	1	no	8.344	-24.025	EPSD	TCGA;COSMIC	8.148	Loss
CMGC_CDK_CDK2_CDK2_ST	Q9NYF8	BCLAF1	P24941	CDK2	S385	A380T	380	Missense	distal	-5	no	8.344	8.318	EPSD	TCGA	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	Q9NYF8	BCLAF1	P24941	CDK2	S389	F394L	394	Missense	distal	5	no	9.361	9.183	EPSD	TCGA;COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	Q9NYF8	BCLAF1	P24941	CDK2	S389	Y383H	383	Missense	distal	-6	no	9.361	9.365	EPSD	TCGA	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	Q9NYF8	BCLAF1	P24941	CDK2	S389	F394Y	394	Missense	distal	5	no	9.361	9.217	EPSD	TCGA;COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	Q9NYF8	BCLAF1	P24941	CDK2	S389	D396Y	396	Missense	distal	7	no	9.361	8.944	EPSD	TCGA;COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	Q9NYF8	BCLAF1	P24941	CDK2	S389	K393M	393	Missense	distal	4	no	9.361	8.539	EPSD	TCGA;COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	Q9NYF8	BCLAF1	P24941	CDK2	S389	K387R	387	Missense	proximal	-2	no	9.361	8.640	EPSD	TCGA;COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	Q9NYF8	BCLAF1	P24941	CDK2	S389	G390E	390	Missense	proximal	1	no	9.361	7.508	EPSD	TCGA;COSMIC	8.148	Loss
CMGC_CDK_CDK2_CDK2_ST	Q9NYF8	BCLAF1	P24941	CDK2	S389	D386N	386	Missense	distal	-3	no	9.361	9.317	EPSD	TCGA;COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	Q9NYF8	BCLAF1	P24941	CDK2	S389	N395S	395	Missense	distal	6	no	9.361	9.359	EPSD	TCGA;COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	Q9NYF8	BCLAF1	P24941	CDK2	T402	S397L	397	Missense	distal	-5	no	8.139	8.196	EPSD	TCGA;COSMIC	8.148	Gain
CMGC_CDK_CDK2_CDK2_ST	Q9NYF8	BCLAF1	P24941	CDK2	T402	E398D	398	Missense	distal	-4	no	8.139	8.436	EPSD	TCGA;COSMIC	8.148	Gain
CMGC_CDK_CDK2_CDK2_ST	Q9NYF8	BCLAF1	P24941	CDK2	T431	E432Q	432	Missense	proximal	1	no	7.189	8.443	EPSD	TCGA;COSMIC	8.148	Gain
CMGC_CDK_CDK2_CDK2_ST	Q9NYF8	BCLAF1	P24941	CDK2	T431	E434K	434	Missense	distal	3	no	7.189	9.274	EPSD	TCGA;COSMIC	8.148	Gain
CMGC_CDK_CDK2_CDK2_ST	Q9NYF8	BCLAF1	P24941	CDK2	T494	I488M	488	Missense	distal	-6	no	8.177	8.182	EPSD	TCGA;COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	Q9NYF8	BCLAF1	P24941	CDK2	T494	V490I	490	Missense	distal	-4	no	8.177	8.075	EPSD	TCGA	8.148	Loss
CMGC_CDK_CDK2_CDK2_ST	Q9NYF8	BCLAF1	P24941	CDK2	T494	Q495L	495	Missense	proximal	1	no	8.177	6.268	EPSD	TCGA;COSMIC	8.148	Loss
CMGC_CDK_CDK2_CDK2_ST	Q9NYF8	BCLAF1	P24941	CDK2	T494	I488L	488	Missense	distal	-6	no	8.177	8.175	EPSD	TCGA;COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	Q9NYF8	BCLAF1	P24941	CDK2	T494	T489R	489	Missense	distal	-5	no	8.177	8.225	EPSD	TCGA;COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	Q9NYF8	BCLAF1	P24941	CDK2	T494	V490L	490	Missense	distal	-4	no	8.177	8.167	EPSD	TCGA;COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	Q9NYF8	BCLAF1	P24941	CDK2	T494	K491N	491	Missense	distal	-3	no	8.177	8.239	EPSD	TCGA;COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	Q9NYF8	BCLAF1	P24941	CDK2	T494	E493D	493	Missense	proximal	-1	no	8.177	8.148	EPSD	TCGA;COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	Q9NYF8	BCLAF1	P24941	CDK2	S496	Q495L	495	Missense	proximal	-1	no	13.721	13.849	EPSD	TCGA;COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	Q9NYF8	BCLAF1	P24941	CDK2	S496	S502F	502	Missense	distal	6	no	13.721	13.702	EPSD	TCGA;COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	Q9NYF8	BCLAF1	P24941	CDK2	S496	T489R	489	Missense	distal	-7	no	13.721	14.067	EPSD	TCGA;COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	Q9NYF8	BCLAF1	P24941	CDK2	S496	V490L	490	Missense	distal	-6	no	13.721	13.719	EPSD	TCGA;COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	Q9NYF8	BCLAF1	P24941	CDK2	S496	K491N	491	Missense	distal	-5	no	13.721	13.737	EPSD	TCGA;COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	Q9NYF8	BCLAF1	P24941	CDK2	S496	E503K	503	Missense	distal	7	no	13.721	13.390	EPSD	TCGA;COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	Q9NYF8	BCLAF1	P24941	CDK2	S496	E493D	493	Missense	distal	-3	no	13.721	13.611	EPSD	TCGA;COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	Q9NYF8	BCLAF1	P24941	CDK2	S512	L515V	515	Missense	distal	3	no	14.296	15.288	EPSD	TCGA;COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	Q9NYF8	BCLAF1	P24941	CDK2	S512	D507Y	507	Missense	distal	-5	no	14.296	14.263	EPSD	TCGA;COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	Q9NYF8	BCLAF1	P24941	CDK2	S512	P513L	513	Missense	proximal	1	no	14.296	4.475	EPSD	TCGA;COSMIC	8.148	Loss
CMGC_CDK_CDK2_CDK2_ST	Q9NYF8	BCLAF1	P24941	CDK2	S512	K517N	517	Missense	distal	5	no	14.296	14.453	EPSD	TCGA;GDSC;CCLE	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	Q9NYF8	BCLAF1	P24941	CDK2	S531	E530K	530	Missense	proximal	-1	no	13.753	12.868	EPSD	TCGA;COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	Q9NYF8	BCLAF1	P24941	CDK2	S531	R534K	534	Missense	distal	3	no	13.753	14.742	EPSD	TCGA;COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	Q9NYF8	BCLAF1	P24941	CDK2	S531	I535N	535	Missense	distal	4	no	13.753	13.761	EPSD	TCGA;COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	Q9NYF8	BCLAF1	P24941	CDK2	S531	I538K	538	Missense	distal	7	no	13.753	13.409	EPSD	TCGA;COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	Q9NYF8	BCLAF1	P24941	CDK2	S542	S542F	542	Missense	central	0	yes	8.937	0.000	EPSD	TCGA;COSMIC;GDSC;CCLE	8.148	Loss
CMGC_CDK_CDK2_CDK2_ST	Q9NYF8	BCLAF1	P24941	CDK2	S542	S542C	542	Missense	central	0	yes	8.937	0.000	EPSD	TCGA;COSMIC	8.148	Loss
CMGC_CDK_CDK2_CDK2_ST	Q9NYF8	BCLAF1	P24941	CDK2	S542	R544H	544	Missense	proximal	2	no	8.937	8.856	EPSD	TCGA;COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	Q9NYF8	BCLAF1	P24941	CDK2	S542	A539T	539	Missense	distal	-3	no	8.937	8.956	EPSD	TCGA;COSMIC;GDSC;CCLE	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	Q9NYF8	BCLAF1	P24941	CDK2	S542	I535N	535	Missense	distal	-7	no	8.937	8.661	EPSD	TCGA;COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	Q9NYF8	BCLAF1	P24941	CDK2	S542	R544C	544	Missense	proximal	2	no	8.937	8.924	EPSD	TCGA;COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	Q9NYF8	BCLAF1	P24941	CDK2	S542	R544S	544	Missense	proximal	2	no	8.937	8.844	EPSD	TCGA;COSMIC;GDSC;CCLE	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	Q9NYF8	BCLAF1	P24941	CDK2	S542	P545L	545	Missense	distal	3	no	8.937	8.553	EPSD	TCGA;COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	Q9NYF8	BCLAF1	P24941	CDK2	S542	I538K	538	Missense	distal	-4	no	8.937	9.007	EPSD	TCGA;COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	Q9NYF8	BCLAF1	P24941	CDK2	S542	A539V	539	Missense	distal	-3	no	8.937	9.138	EPSD	TCGA;COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	Q9NYF8	BCLAF1	P24941	CDK2	S542	S542Y	542	Missense	central	0	yes	8.937	0.000	EPSD	TCGA;COSMIC	8.148	Loss
CMGC_CDK_CDK2_CDK2_ST	Q9NYF8	BCLAF1	P24941	CDK2	S648	E641Q	641	Missense	distal	-7	no	14.636	14.503	EPSD	TCGA;COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	Q9NYF8	BCLAF1	P24941	CDK2	S648	E641K	641	Missense	distal	-7	no	14.636	14.499	EPSD	TCGA	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	Q9NYF8	BCLAF1	P24941	CDK2	S648	R653S	653	Missense	distal	5	no	14.636	14.429	EPSD	TCGA;COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	Q9NYF8	BCLAF1	P24941	CDK2	S658	R653S	653	Missense	distal	-5	no	13.774	13.683	EPSD	TCGA;COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	Q9NYF8	BCLAF1	P24941	CDK2	S718	S718I	718	Missense	central	0	yes	8.581	0.000	EPSD	TCGA;COSMIC	8.148	Loss
CMGC_CDK_CDK2_CDK2_ST	Q9NYF8	BCLAF1	P24941	CDK2	S718	E724K	724	Missense	distal	6	no	8.581	8.592	EPSD	TCGA;COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	Q9NYF8	BCLAF1	P24941	CDK2	T726	P727T	727	Missense	proximal	1	no	10.351	0.394	EPSD	TCGA;COSMIC	8.148	Loss
CMGC_CDK_CDK2_CDK2_ST	Q9NYF8	BCLAF1	P24941	CDK2	T726	E724K	724	Missense	proximal	-2	no	10.351	10.952	EPSD	TCGA;COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	Q9NYF8	BCLAF1	P24941	CDK2	S757	S759F	759	Missense	proximal	2	no	14.470	14.655	EPSD	TCGA;COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	Q9NYF8	BCLAF1	P24941	CDK2	S757	S754F	754	Missense	distal	-3	no	14.470	14.562	EPSD	TCGA;COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	Q9NYF8	BCLAF1	P24941	CDK2	S757	A756E	756	Missense	proximal	-1	no	14.470	15.525	EPSD	TCGA;COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	Q9NYF8	BCLAF1	P24941	CDK2	S757	S753Y	753	Missense	distal	-4	no	14.470	14.581	EPSD	TCGA;COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	Q9NYF8	BCLAF1	P24941	CDK2	S757	R764L	764	Missense	distal	7	no	14.470	14.011	EPSD	TCGA;COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	Q9NYF8	BCLAF1	P24941	CDK2	S757	S763F	763	Missense	distal	6	no	14.470	14.451	EPSD	TCGA;COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	Q9NYF8	BCLAF1	P24941	CDK2	S760	S759F	759	Missense	proximal	-1	no	13.962	15.218	EPSD	TCGA;COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	Q9NYF8	BCLAF1	P24941	CDK2	S760	S754F	754	Missense	distal	-6	no	13.962	13.967	EPSD	TCGA;COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	Q9NYF8	BCLAF1	P24941	CDK2	S760	A756E	756	Missense	distal	-4	no	13.962	14.251	EPSD	TCGA;COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	Q9NYF8	BCLAF1	P24941	CDK2	S760	S753Y	753	Missense	distal	-7	no	13.962	14.268	EPSD	TCGA;COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	Q9NYF8	BCLAF1	P24941	CDK2	S760	R764L	764	Missense	distal	4	no	13.962	14.194	EPSD	TCGA;COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	Q9NYF8	BCLAF1	P24941	CDK2	S760	E765K	765	Missense	distal	5	no	13.962	13.829	EPSD	TCGA;COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	Q9NYF8	BCLAF1	P24941	CDK2	S760	S763F	763	Missense	distal	3	no	13.962	13.887	EPSD	TCGA;COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	Q9NYF8	BCLAF1	P24941	CDK2	S762	E765K	765	Missense	distal	3	no	6.230	8.316	EPSD	TCGA;COSMIC	8.148	Gain
CMGC_CDK_CDK2_CDK2_ST	Q9NYF8	BCLAF1	P24941	CDK2	T840	D836N	836	Missense	distal	-4	no	16.936	16.548	PhosphoSitePlus	TCGA	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	Q9NYF8	BCLAF1	P24941	CDK2	S881	G874W	874	Missense	distal	-7	no	8.068	8.258	EPSD	TCGA	8.148	Gain
CMGC_CDK_CDK2_CDK2_ST	Q9NYF8	BCLAF1	P24941	CDK2	S881	S883C	883	Missense	proximal	2	no	8.068	8.148	EPSD	TCGA;COSMIC	8.148	Gain
CMGC_CDK_CDK2_CDK2_ST	Q9NYF8	BCLAF1	P24941	CDK2	S883	W887L	887	Missense	distal	4	no	9.117	9.709	EPSD	TCGA;COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	Q9NYF8	BCLAF1	P24941	CDK2	S883	G882V	882	Missense	proximal	-1	no	9.117	8.025	EPSD	TCGA;COSMIC	8.148	Loss
CMGC_CDK_CDK2_CDK2_ST	Q9NYF8	BCLAF1	P24941	CDK2	S883	S881L	881	Missense	proximal	-2	no	9.117	9.544	EPSD	TCGA;COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	Q9NYF8	BCLAF1	P24941	CDK2	S883	S883C	883	Missense	central	0	yes	9.117	0.000	EPSD	TCGA;COSMIC	8.148	Loss
CMGC_CDK_CDK2_CDK2_ST	Q9NYF8	BCLAF1	P24941	CDK2	S883	S884T	884	Missense	proximal	1	no	9.117	10.425	EPSD	TCGA;COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	Q9NYF8	BCLAF1	P24941	CDK2	S883	W887R	887	Missense	distal	4	no	9.117	9.476	EPSD	TCGA;COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	Q9NYF8	BCLAF1	P24941	CDK2	S883	P885S	885	Missense	proximal	2	no	9.117	9.183	EPSD	TCGA;COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	Q9NYF8	BCLAF1	P24941	CDK2	S883	H889Y	889	Missense	distal	6	no	9.117	9.114	EPSD	TCGA;COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	Q9NYF8	BCLAF1	P24941	CDK2	S883	N877H	877	Missense	distal	-6	no	9.117	9.121	EPSD	TCGA;COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	Q9NYF8	BCLAF1	P24941	CDK2	S883	K880Q	880	Missense	distal	-3	no	9.117	9.216	EPSD	TCGA;COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	Q9NYF8	BCLAF1	P24941	CDK2	S884	W887L	887	Missense	distal	3	no	11.824	12.362	EPSD	TCGA;COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	Q9NYF8	BCLAF1	P24941	CDK2	S884	G882V	882	Missense	proximal	-2	no	11.824	11.917	EPSD	TCGA;COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	Q9NYF8	BCLAF1	P24941	CDK2	S884	S881L	881	Missense	distal	-3	no	11.824	11.658	EPSD	TCGA;COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	Q9NYF8	BCLAF1	P24941	CDK2	S884	S883C	883	Missense	proximal	-1	no	11.824	12.168	EPSD	TCGA;COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	Q9NYF8	BCLAF1	P24941	CDK2	S884	W887R	887	Missense	distal	3	no	11.824	14.464	EPSD	TCGA;COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	Q9NYF8	BCLAF1	P24941	CDK2	S884	P885S	885	Missense	proximal	1	no	11.824	0.558	EPSD	TCGA;COSMIC	8.148	Loss
CMGC_CDK_CDK2_CDK2_ST	Q9NYF8	BCLAF1	P24941	CDK2	S884	H889Y	889	Missense	distal	5	no	11.824	11.820	EPSD	TCGA;COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	Q9NYF8	BCLAF1	P24941	CDK2	S884	N877H	877	Missense	distal	-7	no	11.824	12.029	EPSD	TCGA;COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	Q9NYF8	BCLAF1	P24941	CDK2	S884	K880Q	880	Missense	distal	-4	no	11.824	11.687	EPSD	TCGA;COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	Q9NYF8	BCLAF1	P24941	CDK2	T888	W887L	887	Missense	proximal	-1	no	11.104	9.800	EPSD	TCGA;COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	Q9NYF8	BCLAF1	P24941	CDK2	T888	G882V	882	Missense	distal	-6	no	11.104	11.103	EPSD	TCGA;COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	Q9NYF8	BCLAF1	P24941	CDK2	T888	S881L	881	Missense	distal	-7	no	11.104	11.289	EPSD	TCGA;COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	Q9NYF8	BCLAF1	P24941	CDK2	T888	S883C	883	Missense	distal	-5	no	11.104	11.229	EPSD	TCGA;COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	Q9NYF8	BCLAF1	P24941	CDK2	T888	S884T	884	Missense	distal	-4	no	11.104	10.916	EPSD	TCGA;COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	Q9NYF8	BCLAF1	P24941	CDK2	T888	W887R	887	Missense	proximal	-1	no	11.104	10.550	EPSD	TCGA;COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	Q9NYF8	BCLAF1	P24941	CDK2	T888	Q893K	893	Missense	distal	5	no	11.104	11.090	EPSD	TCGA;COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	Q9NYF8	BCLAF1	P24941	CDK2	T888	D895N	895	Missense	distal	7	no	11.104	10.324	EPSD	TCGA;COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	Q9NYF8	BCLAF1	P24941	CDK2	T888	P885S	885	Missense	distal	-3	no	11.104	11.199	EPSD	TCGA;COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	Q9NYF8	BCLAF1	P24941	CDK2	T888	H889Y	889	Missense	proximal	1	no	11.104	2.364	EPSD	TCGA;COSMIC	8.148	Loss
CMGC_CDK_CDK2_CDK2_ST	Q9UM11	FZR1	P24941	CDK2	T32	R28W	28	Missense	distal	-4	no	14.341	13.584	EPSD	TCGA;ICGC;COSMIC;GDSC;CCLE	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	Q9UM11	FZR1	P24941	CDK2	T32	P33L	33	Missense	proximal	1	no	14.341	4.521	EPSD	TCGA;ICGC;COSMIC	8.148	Loss
CMGC_CDK_CDK2_CDK2_ST	Q9UM11	FZR1	P24941	CDK2	T32	T32M	32	Missense	central	0	yes	14.341	0.000	EPSD	TCGA;ICGC;COSMIC	8.148	Loss
CMGC_CDK_CDK2_CDK2_ST	Q9UM11	FZR1	P24941	CDK2	S36	P33L	33	Missense	distal	-3	no	13.707	13.636	EPSD	TCGA;ICGC;COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	Q9UM11	FZR1	P24941	CDK2	S36	T32M	32	Missense	distal	-4	no	13.707	12.792	EPSD	TCGA;ICGC;COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	Q9UM11	FZR1	P24941	CDK2	S40	P33L	33	Missense	distal	-7	no	15.649	15.655	PhosphoSitePlus;EPSD	TCGA;ICGC;COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	Q9UM11	FZR1	P24941	CDK2	T121	R115H	115	Missense	distal	-6	no	18.297	18.298	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	Q9UM11	FZR1	P24941	CDK2	S138	S137C	137	Missense	proximal	-1	no	8.586	8.930	EPSD	TCGA;ICGC;COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	Q9UM11	FZR1	P24941	CDK2	S138	D140N	140	Missense	proximal	2	no	8.586	8.519	EPSD	TCGA;ICGC;COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	Q9UM11	FZR1	P24941	CDK2	S138	D144N	144	Missense	distal	6	no	8.586	8.605	EPSD	TCGA;ICGC;COSMIC;GDSC;CCLE	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	Q9UM11	FZR1	P24941	CDK2	S138	S131F	131	Missense	distal	-7	no	8.586	9.138	EPSD	TCGA;ICGC;COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	Q9UM11	FZR1	P24941	CDK2	S146	P152T	152	Missense	distal	6	no	13.003	13.011	EPSD	TCGA;ICGC;COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	Q9UM11	FZR1	P24941	CDK2	S146	D140N	140	Missense	distal	-6	no	13.003	13.005	EPSD	TCGA;ICGC;COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	Q9UM11	FZR1	P24941	CDK2	S146	D144N	144	Missense	proximal	-2	no	13.003	11.795	EPSD	TCGA;ICGC;COSMIC;GDSC;CCLE	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	Q9UM11	FZR1	P24941	CDK2	S146	V153I	153	Missense	distal	7	no	13.003	12.802	EPSD	TCGA;ICGC;COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	Q9UM11	FZR1	P24941	CDK2	S151	P152T	152	Missense	proximal	1	no	12.991	3.033	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	8.148	Loss
CMGC_CDK_CDK2_CDK2_ST	Q9UM11	FZR1	P24941	CDK2	S151	D144N	144	Missense	distal	-7	no	12.991	12.668	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC;GDSC;CCLE	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	Q9UM11	FZR1	P24941	CDK2	S151	V153I	153	Missense	proximal	2	no	12.991	12.845	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	Q9UM11	FZR1	P24941	CDK2	S163	R165Q	165	Missense	proximal	2	no	17.211	17.111	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	Q9UM11	FZR1	P24941	CDK2	S163	T168S	168	Missense	distal	5	no	17.211	17.135	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	Q9UM11	FZR1	P24941	CDK2	S163	R162W	162	Missense	proximal	-1	no	17.211	17.765	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	Q9UM11	FZR1	P24941	CDK2	T300	R307W	307	Missense	distal	7	no	14.296	14.695	EPSD	TCGA	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	Q9UM11	FZR1	P24941	CDK2	S346	S343L	343	Missense	distal	-3	no	11.717	11.551	EPSD	TCGA;COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	P49459	UBE2A	P24941	CDK2	S120	N119T	119	Missense	proximal	-1	no	17.215	17.025	PhosphoSitePlus	TCGA;ICGC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	P49459	UBE2A	P24941	CDK2	S120	S124C	124	Missense	distal	4	no	17.215	16.455	PhosphoSitePlus	TCGA;ICGC;COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	P49459	UBE2A	P24941	CDK2	S120	A127S	127	Missense	distal	7	no	17.215	16.678	PhosphoSitePlus	TCGA;ICGC;COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	P49459	UBE2A	P24941	CDK2	S120	P118S	118	Missense	proximal	-2	no	17.215	16.564	PhosphoSitePlus	TCGA;ICGC;COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	P49459	UBE2A	P24941	CDK2	S124	A127S	127	Missense	distal	3	no	7.649	8.195	EPSD	TCGA;ICGC;COSMIC	8.148	Gain
CMGC_CDK_CDK2_CDK2_ST	P49459	UBE2A	P24941	CDK2	S124	Q131R	131	Missense	distal	7	no	7.649	8.294	EPSD	TCGA;ICGC	8.148	Gain
CMGC_CDK_CDK2_CDK2_ST	Q08050	FOXM1	P24941	CDK2	S4	I10V	10	Missense	distal	6	no	12.345	12.343	EPSD	TCGA;ICGC;COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	Q08050	FOXM1	P24941	CDK2	T252	L259F	259	Missense	distal	7	no	7.541	8.212	EPSD	TCGA;ICGC;COSMIC	8.148	Gain
CMGC_CDK_CDK2_CDK2_ST	Q08050	FOXM1	P24941	CDK2	S340	S340L	340	Missense	central	0	yes	11.158	0.000	EPSD	TCGA;ICGC;COSMIC	8.148	Loss
CMGC_CDK_CDK2_CDK2_ST	Q08050	FOXM1	P24941	CDK2	S591	L588I	588	Missense	distal	-3	no	8.281	8.372	EPSD	TCGA;ICGC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	Q08050	FOXM1	P24941	CDK2	S704	S704N	704	Missense	central	0	yes	17.281	0.000	EPSD	TCGA;ICGC;COSMIC	8.148	Loss
CMGC_CDK_CDK2_CDK2_ST	Q9Y2W1	THRAP3	P24941	CDK2	S22	R23H	23	Missense	proximal	1	no	6.923	9.963	EPSD	TCGA;ICGC;COSMIC	8.148	Gain
CMGC_CDK_CDK2_CDK2_ST	Q9Y2W1	THRAP3	P24941	CDK2	S55	R48S	48	Missense	distal	-7	no	16.095	15.572	EPSD	TCGA;ICGC;COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	Q9Y2W1	THRAP3	P24941	CDK2	S55	R62K	62	Missense	distal	7	no	16.095	15.319	EPSD	TCGA;ICGC;COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	Q9Y2W1	THRAP3	P24941	CDK2	S55	R50C	50	Missense	distal	-5	no	16.095	16.129	EPSD	TCGA;ICGC;COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	Q9Y2W1	THRAP3	P24941	CDK2	S55	R62I	62	Missense	distal	7	no	16.095	15.662	EPSD	TCGA;ICGC;COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	Q9Y2W1	THRAP3	P24941	CDK2	S119	R115W	115	Missense	distal	-4	no	17.576	16.818	EPSD	TCGA;ICGC;COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	Q9Y2W1	THRAP3	P24941	CDK2	S119	R124H	124	Missense	distal	5	no	17.576	17.548	EPSD	TCGA;ICGC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	Q9Y2W1	THRAP3	P24941	CDK2	S134	P135S	135	Missense	proximal	1	no	12.306	1.040	EPSD	TCGA;ICGC;COSMIC	8.148	Loss
CMGC_CDK_CDK2_CDK2_ST	Q9Y2W1	THRAP3	P24941	CDK2	S134	P135L	135	Missense	proximal	1	no	12.306	2.485	EPSD	TCGA;ICGC;COSMIC	8.148	Loss
CMGC_CDK_CDK2_CDK2_ST	Q9Y2W1	THRAP3	P24941	CDK2	S136	P135S	135	Missense	proximal	-1	no	11.087	10.616	EPSD	TCGA;ICGC;COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	Q9Y2W1	THRAP3	P24941	CDK2	S136	P135L	135	Missense	proximal	-1	no	11.087	10.908	EPSD	TCGA;ICGC;COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	Q9Y2W1	THRAP3	P24941	CDK2	S248	S253N	253	Missense	distal	5	no	10.981	11.184	EPSD	TCGA;ICGC;COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	Q9Y2W1	THRAP3	P24941	CDK2	S253	S253N	253	Missense	central	0	yes	14.178	0.000	EPSD	TCGA;ICGC;COSMIC	8.148	Loss
CMGC_CDK_CDK2_CDK2_ST	Q9Y2W1	THRAP3	P24941	CDK2	S264	R266C	266	Missense	proximal	2	no	10.417	10.404	EPSD	TCGA;ICGC;COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	Q9Y2W1	THRAP3	P24941	CDK2	S264	P267T	267	Missense	distal	3	no	10.417	10.302	EPSD	TCGA;ICGC;COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	Q9Y2W1	THRAP3	P24941	CDK2	S264	P267S	267	Missense	distal	3	no	10.417	10.451	EPSD	TCGA;ICGC;COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	Q9Y2W1	THRAP3	P24941	CDK2	S264	P267L	267	Missense	distal	3	no	10.417	10.033	EPSD	TCGA;ICGC;COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	Q9Y2W1	THRAP3	P24941	CDK2	S268	R266C	266	Missense	proximal	-2	no	12.706	12.880	EPSD	TCGA;ICGC;COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	Q9Y2W1	THRAP3	P24941	CDK2	S268	P267T	267	Missense	proximal	-1	no	12.706	12.443	EPSD	TCGA;ICGC;COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	Q9Y2W1	THRAP3	P24941	CDK2	S268	P267S	267	Missense	proximal	-1	no	12.706	12.235	EPSD	TCGA;ICGC;COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	Q9Y2W1	THRAP3	P24941	CDK2	S268	P267L	267	Missense	proximal	-1	no	12.706	12.526	EPSD	TCGA;ICGC;COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	Q9Y2W1	THRAP3	P24941	CDK2	S274	P267T	267	Missense	distal	-7	no	12.230	12.228	EPSD	TCGA;ICGC;COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	Q9Y2W1	THRAP3	P24941	CDK2	S274	P267S	267	Missense	distal	-7	no	12.230	12.050	EPSD	TCGA;ICGC;COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	Q9Y2W1	THRAP3	P24941	CDK2	S274	P267L	267	Missense	distal	-7	no	12.230	12.236	EPSD	TCGA;ICGC;COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	Q9Y2W1	THRAP3	P24941	CDK2	S274	S279N	279	Missense	distal	5	no	12.230	12.434	EPSD	TCGA;ICGC;COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	Q9Y2W1	THRAP3	P24941	CDK2	S310	S308F	308	Missense	proximal	-2	no	16.360	15.898	EPSD	TCGA;ICGC;COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	Q9Y2W1	THRAP3	P24941	CDK2	S310	P311L	311	Missense	proximal	1	no	16.360	6.539	EPSD	TCGA;ICGC;COSMIC;CCLE	8.148	Loss
CMGC_CDK_CDK2_CDK2_ST	Q9Y2W1	THRAP3	P24941	CDK2	S315	G318D	318	Missense	distal	3	no	11.071	9.358	EPSD	TCGA;ICGC;COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	Q9Y2W1	THRAP3	P24941	CDK2	S315	S308F	308	Missense	distal	-7	no	11.071	11.622	EPSD	TCGA;ICGC;COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	Q9Y2W1	THRAP3	P24941	CDK2	S315	P311L	311	Missense	distal	-4	no	11.071	11.012	EPSD	TCGA;ICGC;COSMIC;CCLE	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	Q9Y2W1	THRAP3	P24941	CDK2	S320	G318D	318	Missense	proximal	-2	no	12.934	13.542	EPSD	TCGA;ICGC;COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	Q9Y2W1	THRAP3	P24941	CDK2	S408	R404W	404	Missense	distal	-4	no	14.974	14.217	EPSD	TCGA;ICGC;COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	Q9Y2W1	THRAP3	P24941	CDK2	S408	R415Q	415	Missense	distal	7	no	14.974	14.330	EPSD	TCGA;ICGC;COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	Q9Y2W1	THRAP3	P24941	CDK2	S408	R404Q	404	Missense	distal	-4	no	14.974	14.999	EPSD	TCGA;ICGC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	Q9Y2W1	THRAP3	P24941	CDK2	S535	Q530H	530	Missense	distal	-5	no	11.805	11.852	EPSD	TCGA;ICGC;COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	Q9Y2W1	THRAP3	P24941	CDK2	S535	K540R	540	Missense	distal	5	no	11.805	11.966	EPSD	TCGA;ICGC;COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	Q9Y2W1	THRAP3	P24941	CDK2	S672	P673S	673	Missense	proximal	1	no	11.734	0.468	EPSD	TCGA;ICGC;COSMIC	8.148	Loss
CMGC_CDK_CDK2_CDK2_ST	Q9Y2W1	THRAP3	P24941	CDK2	S698	D694N	694	Missense	distal	-4	no	12.761	12.372	EPSD	TCGA;ICGC;COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	Q9Y2W1	THRAP3	P24941	CDK2	S698	D694V	694	Missense	distal	-4	no	12.761	12.185	EPSD	TCGA;ICGC;COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	Q9Y2W1	THRAP3	P24941	CDK2	S698	K697E	697	Missense	proximal	-1	no	12.761	13.646	EPSD	TCGA;ICGC;COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	Q9Y2W1	THRAP3	P24941	CDK2	S747	S746F	746	Missense	proximal	-1	no	9.521	10.778	EPSD	TCGA;ICGC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	Q9Y2W1	THRAP3	P24941	CDK2	S747	D742A	742	Missense	distal	-5	no	9.521	9.488	EPSD	TCGA;ICGC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	Q9Y2W1	THRAP3	P24941	CDK2	T799	E797D	797	Missense	proximal	-2	no	8.478	9.459	EPSD	TCGA;ICGC;COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	Q9Y2W1	THRAP3	P24941	CDK2	T799	E803D	803	Missense	distal	4	no	8.478	8.396	EPSD	TCGA;ICGC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	Q9Y2W1	THRAP3	P24941	CDK2	T874	P875T	875	Missense	proximal	1	no	13.970	4.013	PhosphoSitePlus	TCGA;ICGC;COSMIC	8.148	Loss
CMGC_CDK_CDK2_CDK2_ST	Q9Y2W1	THRAP3	P24941	CDK2	T874	Y873C	873	Missense	proximal	-1	no	13.970	13.404	PhosphoSitePlus	TCGA;ICGC;COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	Q9Y2W1	THRAP3	P24941	CDK2	S919	A923T	923	Missense	distal	4	no	13.602	13.845	EPSD	TCGA;ICGC;COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	Q9Y2W1	THRAP3	P24941	CDK2	S919	R914W	914	Missense	distal	-5	no	13.602	13.689	EPSD	TCGA;ICGC;COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	Q9Y2W1	THRAP3	P24941	CDK2	S919	R914Q	914	Missense	distal	-5	no	13.602	13.555	EPSD	TCGA;ICGC;COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	Q9H425	C1orf198	P24941	CDK2	S17	L22V	22	Missense	distal	5	no	9.478	9.405	EPSD	TCGA;ICGC;COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	Q9H425	C1orf198	P24941	CDK2	S17	R12L	12	Missense	distal	-5	no	9.478	9.443	EPSD	TCGA;ICGC;COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	Q9H425	C1orf198	P24941	CDK2	S175	L176P	176	Missense	proximal	1	no	6.016	15.837	EPSD	TCGA;COSMIC	8.148	Gain
CMGC_CDK_CDK2_CDK2_ST	Q9H425	C1orf198	P24941	CDK2	T211	A205V	205	Missense	distal	-6	no	14.429	14.432	EPSD	TCGA;COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	Q9H425	C1orf198	P24941	CDK2	T211	L210M	210	Missense	proximal	-1	no	14.429	15.658	EPSD	TCGA;COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	Q9H425	C1orf198	P24941	CDK2	S213	L210M	210	Missense	distal	-3	no	8.050	8.489	EPSD	TCGA;COSMIC	8.148	Gain
CMGC_CDK_CDK2_CDK2_ST	Q9H425	C1orf198	P24941	CDK2	S289	D296N	296	Missense	distal	7	no	12.988	12.208	EPSD	TCGA	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	Q9H425	C1orf198	P24941	CDK2	S289	P288S	288	Missense	proximal	-1	no	12.988	12.517	EPSD	TCGA;COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	Q9H425	C1orf198	P24941	CDK2	S289	G285R	285	Missense	distal	-4	no	12.988	13.063	EPSD	TCGA	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	P15927	RPA2	P24941	CDK2	S23	T21P	21	Missense	proximal	-2	no	12.634	12.667	EPSD;PhosphoSitePlus	TCGA	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	P15927	RPA2	P24941	CDK2	S23	S23F	23	Missense	central	0	yes	12.634	0.000	EPSD;PhosphoSitePlus	TCGA;COSMIC	8.148	Loss
CMGC_CDK_CDK2_CDK2_ST	P15927	RPA2	P24941	CDK2	S23	G19D	19	Missense	distal	-4	no	12.634	13.479	EPSD;PhosphoSitePlus	TCGA;COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	P15927	RPA2	P24941	CDK2	S23	G26S	26	Missense	distal	3	no	12.634	12.769	EPSD;PhosphoSitePlus	TCGA;COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	P15927	RPA2	P24941	CDK2	S29	S23F	23	Missense	distal	-6	no	13.746	13.751	PhosphoSitePlus;EPSD	TCGA;COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	P15927	RPA2	P24941	CDK2	S29	E36A	36	Missense	distal	7	no	13.746	14.087	PhosphoSitePlus;EPSD	TCGA;COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	P15927	RPA2	P24941	CDK2	S29	S29L	29	Missense	central	0	yes	13.746	0.000	PhosphoSitePlus;EPSD	TCGA;COSMIC	8.148	Loss
CMGC_CDK_CDK2_CDK2_ST	P15927	RPA2	P24941	CDK2	S29	G26S	26	Missense	distal	-3	no	13.746	13.738	PhosphoSitePlus;EPSD	TCGA;COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	P15927	RPA2	P24941	CDK2	S33	E36A	36	Missense	distal	3	no	9.960	8.826	EPSD;PhosphoSitePlus	TCGA;COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	P15927	RPA2	P24941	CDK2	S33	S29L	29	Missense	distal	-4	no	9.960	9.548	EPSD;PhosphoSitePlus	TCGA;COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	P15927	RPA2	P24941	CDK2	S33	G26S	26	Missense	distal	-7	no	9.960	9.456	EPSD;PhosphoSitePlus	TCGA;COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	P15927	RPA2	P24941	CDK2	S33	S39A	39	Missense	distal	6	no	9.960	9.955	EPSD;PhosphoSitePlus	TCGA;COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	P49736	MCM2	P24941	CDK2	S13	R18W	18	Missense	distal	5	no	13.598	13.764	EPSD;PhosphoSitePlus	TCGA;ICGC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	P49736	MCM2	P24941	CDK2	S13	T9I	9	Missense	distal	-4	no	13.598	13.280	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	P49736	MCM2	P24941	CDK2	S27	D22G	22	Missense	distal	-5	no	15.798	15.820	EPSD;PhosphoSitePlus	TCGA;ICGC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	P49736	MCM2	P24941	CDK2	S41	D36N	36	Missense	distal	-5	no	15.832	15.794	PhosphoSitePlus;EPSD	TCGA;ICGC;COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	P49736	MCM2	P24941	CDK2	S41	L38I	38	Missense	distal	-3	no	15.832	15.923	PhosphoSitePlus;EPSD	TCGA;ICGC;COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	P49736	MCM2	P24941	CDK2	S53	D51H	51	Missense	proximal	-2	no	8.480	7.604	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	8.148	Loss
CMGC_CDK_CDK2_CDK2_ST	P49736	MCM2	P24941	CDK2	S53	E50D	50	Missense	distal	-3	no	8.480	8.370	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	P49736	MCM2	P24941	CDK2	S108	E111G	111	Missense	distal	3	no	9.985	9.262	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	P49736	MCM2	P24941	CDK2	S139	R146H	146	Missense	distal	7	no	8.904	8.546	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	P49736	MCM2	P24941	CDK2	S139	E145K	145	Missense	distal	6	no	8.904	8.915	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	P49736	MCM2	P24941	CDK2	S139	R132H	132	Missense	distal	-7	no	8.904	8.684	EPSD;PhosphoSitePlus	TCGA;ICGC;CCLE	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	P49736	MCM2	P24941	CDK2	S209	S209N	209	Missense	central	0	yes	9.821	0.000	EPSD	TCGA;ICGC;COSMIC	8.148	Loss
CMGC_CDK_CDK2_CDK2_ST	P49736	MCM2	P24941	CDK2	S209	N213D	213	Missense	distal	4	no	9.821	9.776	EPSD	TCGA;ICGC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	P49736	MCM2	P24941	CDK2	S381	P382S	382	Missense	proximal	1	no	17.631	6.365	EPSD	TCGA;ICGC	8.148	Loss
CMGC_CDK_CDK2_CDK2_ST	P49736	MCM2	P24941	CDK2	T805	R812C	812	Missense	distal	7	no	9.534	9.685	EPSD	TCGA;ICGC;COSMIC;GDSC;CCLE	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	P49736	MCM2	P24941	CDK2	T805	R812H	812	Missense	distal	7	no	9.534	9.176	EPSD	TCGA;ICGC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	P55273	CDKN2D	P24941	CDK2	S66	S73C	73	Missense	distal	7	no	14.025	14.818	EPSD	TCGA;ICGC;COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	P55273	CDKN2D	P24941	CDK2	S76	S73C	73	Missense	distal	-3	no	15.359	15.367	PhosphoSitePlus	TCGA;ICGC;COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	P55273	CDKN2D	P24941	CDK2	T141	R135S	135	Missense	distal	-6	no	15.112	15.109	EPSD	TCGA;ICGC;COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	P55273	CDKN2D	P24941	CDK2	T141	R134H	134	Missense	distal	-7	no	15.112	14.891	EPSD	TCGA;ICGC;COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	Q14191	WRN	P24941	CDK2	S179	V181A	181	Missense	proximal	2	no	8.451	8.353	EPSD	TCGA;ICGC;COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	Q14191	WRN	P24941	CDK2	S179	G186V	186	Missense	distal	7	no	8.451	8.040	EPSD	TCGA	8.148	Loss
CMGC_CDK_CDK2_CDK2_ST	Q14191	WRN	P24941	CDK2	S426	E431K	431	Missense	distal	5	no	12.318	12.185	EPSD	TCGA;ICGC;COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	Q14191	WRN	P24941	CDK2	S426	T422S	422	Missense	distal	-4	no	12.318	12.506	EPSD	TCGA;ICGC;COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	Q14191	WRN	P24941	CDK2	S426	P427S	427	Missense	proximal	1	no	12.318	1.052	EPSD	TCGA;ICGC;COSMIC	8.148	Loss
CMGC_CDK_CDK2_CDK2_ST	Q14191	WRN	P24941	CDK2	S426	N430Y	430	Missense	distal	4	no	12.318	12.537	EPSD	TCGA;ICGC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	Q14191	WRN	P24941	CDK2	T490	S484R	484	Missense	distal	-6	no	9.946	9.949	EPSD	TCGA;ICGC;COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	Q14191	WRN	P24941	CDK2	S547	Y543H	543	Missense	distal	-4	no	9.595	8.525	EPSD	TCGA;ICGC;COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	Q14191	WRN	P24941	CDK2	T629	G634V	634	Missense	distal	5	no	8.331	8.172	EPSD	TCGA;ICGC;COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	Q14191	WRN	P24941	CDK2	S1133	S1140P	1140	Missense	distal	7	no	16.492	16.644	PhosphoSitePlus	TCGA;ICGC;COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	Q14191	WRN	P24941	CDK2	S1139	S1140P	1140	Missense	proximal	1	no	4.249	15.514	EPSD	TCGA;ICGC;COSMIC	8.148	Gain
CMGC_CDK_CDK2_CDK2_ST	Q14191	WRN	P24941	CDK2	S1292	S1292F	1292	Missense	central	0	yes	9.597	0.000	EPSD	TCGA;ICGC;COSMIC	8.148	Loss
CMGC_CDK_CDK2_CDK2_ST	Q14191	WRN	P24941	CDK2	S1292	A1294V	1294	Missense	proximal	2	no	9.597	9.695	EPSD	TCGA;ICGC;COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	Q7Z2Z1	TICRR	P24941	CDK2	S120	P124L	124	Missense	distal	4	no	18.017	18.129	EPSD	TCGA;ICGC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	Q7Z2Z1	TICRR	P24941	CDK2	S441	S447F	447	Missense	distal	6	no	13.855	13.836	EPSD	TCGA;ICGC;COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	Q7Z2Z1	TICRR	P24941	CDK2	S441	R443W	443	Missense	proximal	2	no	13.855	13.953	EPSD	TCGA;ICGC;COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	Q7Z2Z1	TICRR	P24941	CDK2	T566	R565C	565	Missense	proximal	-1	no	16.179	15.481	EPSD	TCGA;ICGC;COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	Q7Z2Z1	TICRR	P24941	CDK2	S599	D601V	601	Missense	proximal	2	no	15.711	15.837	EPSD	TCGA;ICGC;COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	Q7Z2Z1	TICRR	P24941	CDK2	S838	D842N	842	Missense	distal	4	no	13.163	13.208	EPSD	TCGA;ICGC;COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	Q7Z2Z1	TICRR	P24941	CDK2	S923	L916I	916	Missense	distal	-7	no	14.714	14.903	EPSD	TCGA;ICGC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	Q7Z2Z1	TICRR	P24941	CDK2	S936	R931Q	931	Missense	distal	-5	no	10.012	9.965	EPSD	TCGA;ICGC;COSMIC;GDSC;CCLE	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	Q7Z2Z1	TICRR	P24941	CDK2	T969	I975V	975	Missense	distal	6	no	17.379	17.377	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	Q7Z2Z1	TICRR	P24941	CDK2	T969	T963S	963	Missense	distal	-6	no	17.379	17.378	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	Q7Z2Z1	TICRR	P24941	CDK2	S1001	S1001Y	1001	Missense	central	0	yes	16.333	0.000	PhosphoSitePlus;EPSD	TCGA;ICGC;COSMIC	8.148	Loss
CMGC_CDK_CDK2_CDK2_ST	Q7Z2Z1	TICRR	P24941	CDK2	S1013	R1015Q	1015	Missense	proximal	2	no	12.891	12.791	EPSD	TCGA;ICGC;COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	Q7Z2Z1	TICRR	P24941	CDK2	S1033	S1031C	1031	Missense	proximal	-2	no	11.049	10.638	EPSD	TCGA;ICGC;COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	Q7Z2Z1	TICRR	P24941	CDK2	S1033	A1027V	1027	Missense	distal	-6	no	11.049	11.051	EPSD	TCGA;ICGC;COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	Q7Z2Z1	TICRR	P24941	CDK2	S1033	P1035S	1035	Missense	proximal	2	no	11.049	11.115	EPSD	TCGA;ICGC;COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	Q7Z2Z1	TICRR	P24941	CDK2	S1033	R1038Q	1038	Missense	distal	5	no	11.049	10.902	EPSD	TCGA;ICGC;COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	Q7Z2Z1	TICRR	P24941	CDK2	S1033	S1033P	1033	Missense	central	0	yes	11.049	0.000	EPSD	TCGA;ICGC	8.148	Loss
CMGC_CDK_CDK2_CDK2_ST	Q7Z2Z1	TICRR	P24941	CDK2	S1037	R1038Q	1038	Missense	proximal	1	no	6.699	8.586	EPSD	TCGA;ICGC;COSMIC	8.148	Gain
CMGC_CDK_CDK2_CDK2_ST	Q7Z2Z1	TICRR	P24941	CDK2	S1057	R1054K	1054	Missense	distal	-3	no	11.084	10.855	EPSD	TCGA;ICGC;COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	Q7Z2Z1	TICRR	P24941	CDK2	S1057	D1052E	1052	Missense	distal	-5	no	11.084	11.064	EPSD	TCGA;ICGC;COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	Q7Z2Z1	TICRR	P24941	CDK2	S1057	R1063W	1063	Missense	distal	6	no	11.084	11.077	EPSD	TCGA;ICGC;COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	Q7Z2Z1	TICRR	P24941	CDK2	S1064	L1069I	1069	Missense	distal	5	no	14.114	14.166	EPSD	TCGA;ICGC;COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	Q7Z2Z1	TICRR	P24941	CDK2	S1064	R1063W	1063	Missense	proximal	-1	no	14.114	14.668	EPSD	TCGA;ICGC;COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	Q7Z2Z1	TICRR	P24941	CDK2	S1078	M1076I	1076	Missense	proximal	-2	no	14.068	15.998	EPSD	TCGA;ICGC;COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	Q7Z2Z1	TICRR	P24941	CDK2	T1105	Q1104H	1104	Missense	proximal	-1	no	14.479	14.906	EPSD	TCGA;ICGC;COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	Q7Z2Z1	TICRR	P24941	CDK2	S1109	Q1104H	1104	Missense	distal	-5	no	10.138	10.185	EPSD	TCGA;ICGC;COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	Q7Z2Z1	TICRR	P24941	CDK2	T1120	I1124M	1124	Missense	distal	4	no	12.660	12.268	EPSD	TCGA;ICGC;COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	Q7Z2Z1	TICRR	P24941	CDK2	T1120	S1125C	1125	Missense	distal	5	no	12.660	12.995	EPSD	TCGA;ICGC;COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	Q7Z2Z1	TICRR	P24941	CDK2	T1120	P1121A	1121	Missense	proximal	1	no	12.660	-1.743	EPSD	TCGA;ICGC;COSMIC;GDSC;CCLE	8.148	Loss
CMGC_CDK_CDK2_CDK2_ST	Q7Z2Z1	TICRR	P24941	CDK2	T1127	I1124M	1124	Missense	distal	-3	no	9.261	9.609	EPSD	TCGA;ICGC;COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	Q7Z2Z1	TICRR	P24941	CDK2	T1127	S1125C	1125	Missense	proximal	-2	no	9.261	8.851	EPSD	TCGA;ICGC;COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	Q7Z2Z1	TICRR	P24941	CDK2	T1127	P1121A	1121	Missense	distal	-6	no	9.261	9.260	EPSD	TCGA;ICGC;COSMIC;GDSC;CCLE	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	Q7Z2Z1	TICRR	P24941	CDK2	T1130	I1124M	1124	Missense	distal	-6	no	15.757	15.762	EPSD	TCGA;ICGC;COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	Q7Z2Z1	TICRR	P24941	CDK2	T1130	S1125C	1125	Missense	distal	-5	no	15.757	15.882	EPSD	TCGA;ICGC;COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	Q7Z2Z1	TICRR	P24941	CDK2	T1130	E1136Q	1136	Missense	distal	6	no	15.757	15.765	EPSD	TCGA;ICGC;COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	Q7Z2Z1	TICRR	P24941	CDK2	T1134	E1136Q	1136	Missense	proximal	2	no	15.645	15.607	EPSD	TCGA;ICGC;COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	Q7Z2Z1	TICRR	P24941	CDK2	S1141	E1136Q	1136	Missense	distal	-5	no	12.640	12.603	EPSD	TCGA;ICGC;COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	Q7Z2Z1	TICRR	P24941	CDK2	S1162	S1167L	1167	Missense	distal	5	no	13.627	13.768	EPSD	TCGA;ICGC;COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	Q7Z2Z1	TICRR	P24941	CDK2	S1162	L1157F	1157	Missense	distal	-5	no	13.627	13.688	EPSD	TCGA;ICGC;COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	Q7Z2Z1	TICRR	P24941	CDK2	S1167	S1167L	1167	Missense	central	0	yes	10.581	0.000	EPSD	TCGA;ICGC;COSMIC	8.148	Loss
CMGC_CDK_CDK2_CDK2_ST	Q7Z2Z1	TICRR	P24941	CDK2	T1174	S1167L	1167	Missense	distal	-7	no	15.977	16.163	EPSD	TCGA;ICGC;COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	Q7Z2Z1	TICRR	P24941	CDK2	T1192	T1186I	1186	Missense	distal	-6	no	11.791	11.793	EPSD	TCGA;ICGC;COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	Q7Z2Z1	TICRR	P24941	CDK2	S1219	S1224C	1224	Missense	distal	5	no	12.313	12.648	EPSD	TCGA;ICGC;COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	Q7Z2Z1	TICRR	P24941	CDK2	S1219	H1214Y	1214	Missense	distal	-5	no	12.313	12.290	EPSD	TCGA;ICGC;COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	Q7Z2Z1	TICRR	P24941	CDK2	S1222	S1224C	1224	Missense	proximal	2	no	8.606	8.685	EPSD	TCGA;ICGC;COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	Q7Z2Z1	TICRR	P24941	CDK2	T1242	P1236S	1236	Missense	distal	-6	no	14.880	14.878	EPSD	TCGA;ICGC;COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	Q7Z2Z1	TICRR	P24941	CDK2	T1250	A1256T	1256	Missense	distal	6	no	14.822	14.833	EPSD	TCGA;ICGC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	Q7Z2Z1	TICRR	P24941	CDK2	T1260	A1256T	1256	Missense	distal	-4	no	12.789	13.014	EPSD	TCGA;ICGC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	Q7Z2Z1	TICRR	P24941	CDK2	T1291	D1286E	1286	Missense	distal	-5	no	15.267	15.247	EPSD	TCGA	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	Q7Z2Z1	TICRR	P24941	CDK2	T1291	P1295T	1295	Missense	distal	4	no	15.267	15.550	EPSD	TCGA;ICGC;COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	Q7Z2Z1	TICRR	P24941	CDK2	T1291	L1284R	1284	Missense	distal	-7	no	15.267	15.605	EPSD	TCGA;ICGC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	Q7Z2Z1	TICRR	P24941	CDK2	S1303	P1305L	1305	Missense	proximal	2	no	15.541	15.434	EPSD	TCGA;ICGC;COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	Q7Z2Z1	TICRR	P24941	CDK2	T1307	F1312L	1312	Missense	distal	5	no	13.313	13.135	EPSD	TCGA;ICGC;COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	Q7Z2Z1	TICRR	P24941	CDK2	T1307	T1313I	1313	Missense	distal	6	no	13.313	13.305	EPSD	TCGA;ICGC;COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	Q7Z2Z1	TICRR	P24941	CDK2	T1307	P1305L	1305	Missense	proximal	-2	no	13.313	13.088	EPSD	TCGA;ICGC;COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	Q7Z2Z1	TICRR	P24941	CDK2	S1323	K1322N	1322	Missense	proximal	-1	no	14.953	14.980	EPSD	TCGA;ICGC;COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	Q7Z2Z1	TICRR	P24941	CDK2	S1323	S1328Y	1328	Missense	distal	5	no	14.953	15.128	EPSD	TCGA;ICGC;COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	Q7Z2Z1	TICRR	P24941	CDK2	S1334	G1336R	1336	Missense	proximal	2	no	13.654	13.695	EPSD	TCGA;ICGC;COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	Q7Z2Z1	TICRR	P24941	CDK2	S1346	E1342K	1342	Missense	distal	-4	no	16.971	16.660	EPSD	TCGA;ICGC;COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	Q7Z2Z1	TICRR	P24941	CDK2	T1360	T1360A	1360	Missense	central	0	yes	13.488	0.000	EPSD	TCGA;ICGC;COSMIC	8.148	Loss
CMGC_CDK_CDK2_CDK2_ST	Q7Z2Z1	TICRR	P24941	CDK2	T1360	P1362S	1362	Missense	proximal	2	no	13.488	13.554	EPSD	TCGA;ICGC;COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	Q7Z2Z1	TICRR	P24941	CDK2	T1405	Q1399P	1399	Missense	distal	-6	no	13.966	13.963	EPSD	TCGA;ICGC;COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	Q7Z2Z1	TICRR	P24941	CDK2	S1413	D1419Y	1419	Missense	distal	6	no	13.924	13.931	EPSD	TCGA;ICGC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	Q7Z2Z1	TICRR	P24941	CDK2	S1430	G1426R	1426	Missense	distal	-4	no	13.042	13.117	EPSD	TCGA;ICGC;COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	Q7Z2Z1	TICRR	P24941	CDK2	S1430	P1435L	1435	Missense	distal	5	no	13.042	13.082	EPSD	TCGA;ICGC;COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	Q7Z2Z1	TICRR	P24941	CDK2	S1430	Q1424R	1424	Missense	distal	-6	no	13.042	13.041	EPSD	TCGA;ICGC;COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	Q7Z2Z1	TICRR	P24941	CDK2	S1433	G1426R	1426	Missense	distal	-7	no	15.113	15.132	EPSD	TCGA;ICGC;COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	Q7Z2Z1	TICRR	P24941	CDK2	S1433	P1435L	1435	Missense	proximal	2	no	15.113	15.006	EPSD	TCGA;ICGC;COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	Q7Z2Z1	TICRR	P24941	CDK2	S1447	S1447R	1447	Missense	central	0	yes	9.800	0.000	EPSD	TCGA;ICGC;COSMIC	8.148	Loss
CMGC_CDK_CDK2_CDK2_ST	Q7Z2Z1	TICRR	P24941	CDK2	S1447	L1445F	1445	Missense	proximal	-2	no	9.800	8.911	EPSD	TCGA;ICGC;COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	Q7Z2Z1	TICRR	P24941	CDK2	S1453	S1447R	1447	Missense	distal	-6	no	14.539	14.542	EPSD	TCGA;ICGC;COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	Q7Z2Z1	TICRR	P24941	CDK2	S1517	R1523H	1523	Missense	distal	6	no	14.740	14.751	EPSD	TCGA;ICGC;COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	Q7Z2Z1	TICRR	P24941	CDK2	S1555	S1550F	1550	Missense	distal	-5	no	12.375	12.492	EPSD	TCGA;ICGC;COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	Q7Z2Z1	TICRR	P24941	CDK2	S1555	T1551I	1551	Missense	distal	-4	no	12.375	12.058	EPSD	TCGA;ICGC;COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	Q7Z2Z1	TICRR	P24941	CDK2	T1668	D1663H	1663	Missense	distal	-5	no	18.301	18.290	EPSD	TCGA;ICGC;COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	Q7Z2Z1	TICRR	P24941	CDK2	T1668	S1670F	1670	Missense	proximal	2	no	18.301	18.485	EPSD	TCGA;ICGC;COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	Q7Z2Z1	TICRR	P24941	CDK2	T1668	P1666T	1666	Missense	proximal	-2	no	18.301	18.267	EPSD	TCGA;ICGC;COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	Q7Z2Z1	TICRR	P24941	CDK2	S1670	D1663H	1663	Missense	distal	-7	no	16.075	15.957	EPSD	TCGA;ICGC;COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	Q7Z2Z1	TICRR	P24941	CDK2	S1670	S1670F	1670	Missense	central	0	yes	16.075	0.000	EPSD	TCGA;ICGC;COSMIC	8.148	Loss
CMGC_CDK_CDK2_CDK2_ST	Q7Z2Z1	TICRR	P24941	CDK2	S1670	P1666T	1666	Missense	distal	-4	no	16.075	16.241	EPSD	TCGA;ICGC;COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	Q7Z2Z1	TICRR	P24941	CDK2	S1718	G1724S	1724	Missense	distal	6	no	9.198	9.210	EPSD	TCGA;ICGC;COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	Q7Z2Z1	TICRR	P24941	CDK2	T1732	S1728N	1728	Missense	distal	-4	no	11.807	11.591	EPSD	TCGA;ICGC;COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	Q7Z2Z1	TICRR	P24941	CDK2	S1750	S1750P	1750	Missense	central	0	yes	16.013	0.000	EPSD	TCGA;ICGC;COSMIC	8.148	Loss
CMGC_CDK_CDK2_CDK2_ST	Q7Z2Z1	TICRR	P24941	CDK2	T1828	S1827C	1827	Missense	proximal	-1	no	12.561	12.905	EPSD	TCGA;ICGC;COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	Q7Z2Z1	TICRR	P24941	CDK2	T1828	E1821Q	1821	Missense	distal	-7	no	12.561	12.428	EPSD	TCGA;ICGC;COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	Q7Z2Z1	TICRR	P24941	CDK2	T1828	G1826C	1826	Missense	proximal	-2	no	12.561	12.242	EPSD	TCGA;ICGC;COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	Q7Z2Z1	TICRR	P24941	CDK2	S1850	P1851L	1851	Missense	proximal	1	no	12.937	3.117	EPSD	TCGA;ICGC;COSMIC;GDSC;CCLE	8.148	Loss
CMGC_CDK_CDK2_CDK2_ST	Q7Z2Z1	TICRR	P24941	CDK2	S1881	S1888F	1888	Missense	distal	7	no	13.327	14.181	EPSD	TCGA;ICGC;COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	Q7Z2Z1	TICRR	P24941	CDK2	T1898	T1896A	1896	Missense	proximal	-2	no	10.071	10.121	EPSD	TCGA;ICGC;COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	Q7Z2Z1	TICRR	P24941	CDK2	T1898	T1896I	1896	Missense	proximal	-2	no	10.071	9.950	EPSD	TCGA;ICGC;COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	Q7Z2Z1	TICRR	P24941	CDK2	T1898	R1891C	1891	Missense	distal	-7	no	10.071	9.998	EPSD	TCGA;ICGC;COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	Q9NP87	POLM	P24941	CDK2	S12	D16N	16	Missense	distal	4	no	13.841	13.885	EPSD	TCGA;ICGC;COSMIC;CCLE	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	Q9NP87	POLM	P24941	CDK2	T21	D16N	16	Missense	distal	-5	no	11.040	11.001	EPSD	TCGA;ICGC;COSMIC;CCLE	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	Q9NP87	POLM	P24941	CDK2	T95	G93C	93	Missense	proximal	-2	no	12.319	12.000	EPSD	TCGA;ICGC;COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	P33991	MCM4	P24941	CDK2	T19	R25W	25	Missense	distal	6	no	13.630	13.622	EPSD	TCGA;ICGC;COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	P33991	MCM4	P24941	CDK2	T23	R25W	25	Missense	proximal	2	no	12.603	12.700	EPSD	TCGA;ICGC;COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	P33991	MCM4	P24941	CDK2	T23	A29S	29	Missense	distal	6	no	12.603	12.608	EPSD	TCGA;ICGC;COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	P33991	MCM4	P24941	CDK2	T23	A29D	29	Missense	distal	6	no	12.603	12.592	EPSD	TCGA;ICGC;COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	P33991	MCM4	P24941	CDK2	S32	S32C	32	Missense	central	0	yes	13.864	0.000	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	8.148	Loss
CMGC_CDK_CDK2_CDK2_ST	P33991	MCM4	P24941	CDK2	S32	R25W	25	Missense	distal	-7	no	13.864	14.035	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	P33991	MCM4	P24941	CDK2	S32	G39D	39	Missense	distal	7	no	13.864	13.880	EPSD;PhosphoSitePlus	TCGA;ICGC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	P33991	MCM4	P24941	CDK2	S32	A29S	29	Missense	distal	-3	no	13.864	14.018	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	P33991	MCM4	P24941	CDK2	S32	A29D	29	Missense	distal	-3	no	13.864	13.987	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	P33991	MCM4	P24941	CDK2	S32	P33L	33	Missense	proximal	1	no	13.864	4.043	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	8.148	Loss
CMGC_CDK_CDK2_CDK2_ST	P33991	MCM4	P24941	CDK2	S54	S54L	54	Missense	central	0	yes	15.106	0.000	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	8.148	Loss
CMGC_CDK_CDK2_CDK2_ST	P33991	MCM4	P24941	CDK2	S61	V67M	67	Missense	distal	6	no	10.740	10.723	EPSD	TCGA;ICGC;COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	P33991	MCM4	P24941	CDK2	S61	S54L	54	Missense	distal	-7	no	10.740	10.926	EPSD	TCGA;ICGC;COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	P33991	MCM4	P24941	CDK2	S71	F69S	69	Missense	proximal	-2	no	11.911	12.373	EPSD	TCGA;ICGC;COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	P33991	MCM4	P24941	CDK2	S71	V67M	67	Missense	distal	-4	no	11.911	11.211	EPSD	TCGA;ICGC;COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	P33991	MCM4	P24941	CDK2	S71	H76R	76	Missense	distal	5	no	11.911	11.939	EPSD	TCGA;ICGC;COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	P33991	MCM4	P24941	CDK2	S71	S77Y	77	Missense	distal	6	no	11.911	11.902	EPSD	TCGA;ICGC;COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	P33991	MCM4	P24941	CDK2	S88	Y92C	92	Missense	distal	4	no	11.564	10.618	EPSD	TCGA;ICGC;COSMIC;GDSC;CCLE	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	P33991	MCM4	P24941	CDK2	S88	D83Y	83	Missense	distal	-5	no	11.564	11.531	EPSD	TCGA;ICGC;COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	P33991	MCM4	P24941	CDK2	S88	S87I	87	Missense	proximal	-1	no	11.564	12.018	EPSD	TCGA;ICGC;COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	P33991	MCM4	P24941	CDK2	T94	Y92C	92	Missense	proximal	-2	no	13.486	12.989	EPSD	TCGA;ICGC;COSMIC;GDSC;CCLE	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	P33991	MCM4	P24941	CDK2	T94	S87I	87	Missense	distal	-7	no	13.486	13.860	EPSD	TCGA;ICGC;COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	P33991	MCM4	P24941	CDK2	T94	R98Q	98	Missense	distal	4	no	13.486	13.667	EPSD	TCGA;ICGC;COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	P33991	MCM4	P24941	CDK2	T102	R98Q	98	Missense	distal	-4	no	13.992	14.017	EPSD	TCGA;ICGC;COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	P33991	MCM4	P24941	CDK2	S105	R98Q	98	Missense	distal	-7	no	8.680	8.293	EPSD	TCGA;ICGC;COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	P33991	MCM4	P24941	CDK2	S357	G364E	364	Missense	distal	7	no	12.710	12.085	EPSD	TCGA;ICGC;COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	P33991	MCM4	P24941	CDK2	T815	A817V	817	Missense	proximal	2	no	12.407	12.504	EPSD	TCGA;ICGC;COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	P33991	MCM4	P24941	CDK2	T815	L810V	810	Missense	distal	-5	no	12.407	12.426	EPSD	TCGA;ICGC;COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	P06401	PGR	P24941	CDK2	S20	S25F	25	Missense	distal	5	no	13.421	13.740	EPSD	TCGA;ICGC;COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	P06401	PGR	P24941	CDK2	S20	S20F	20	Missense	central	0	yes	13.421	0.000	EPSD	TCGA;ICGC;COSMIC	8.148	Loss
CMGC_CDK_CDK2_CDK2_ST	P06401	PGR	P24941	CDK2	S20	L27P	27	Missense	distal	7	no	13.421	13.391	EPSD	TCGA;ICGC;COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	P06401	PGR	P24941	CDK2	S25	S25F	25	Missense	central	0	yes	14.293	0.000	EPSD	TCGA;ICGC;COSMIC	8.148	Loss
CMGC_CDK_CDK2_CDK2_ST	P06401	PGR	P24941	CDK2	S25	S20F	20	Missense	distal	-5	no	14.293	14.410	EPSD	TCGA;ICGC;COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	P06401	PGR	P24941	CDK2	S25	L27P	27	Missense	proximal	2	no	14.293	14.400	EPSD	TCGA;ICGC;COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	P06401	PGR	P24941	CDK2	S102	G109R	109	Missense	distal	7	no	14.184	14.004	EPSD	TCGA;ICGC;COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	P06401	PGR	P24941	CDK2	S102	S102I	102	Missense	central	0	yes	14.184	0.000	EPSD	TCGA;ICGC	8.148	Loss
CMGC_CDK_CDK2_CDK2_ST	P06401	PGR	P24941	CDK2	S102	S101C	101	Missense	proximal	-1	no	14.184	14.528	EPSD	TCGA;ICGC;COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	P06401	PGR	P24941	CDK2	S102	S108I	108	Missense	distal	6	no	14.184	14.183	EPSD	TCGA;ICGC;COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	P06401	PGR	P24941	CDK2	S130	P132S	132	Missense	proximal	2	no	12.920	12.987	EPSD	TCGA;ICGC;COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	P06401	PGR	P24941	CDK2	S190	L197F	197	Missense	distal	7	no	14.476	15.147	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	P06401	PGR	P24941	CDK2	S213	A218V	218	Missense	distal	5	no	14.599	14.556	EPSD;PhosphoSitePlus	TCGA;ICGC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	P06401	PGR	P24941	CDK2	S294	T299A	299	Missense	distal	5	no	13.753	13.789	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	P06401	PGR	P24941	CDK2	S294	A287E	287	Missense	distal	-7	no	13.753	13.679	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	P06401	PGR	P24941	CDK2	S294	R293C	293	Missense	proximal	-1	no	13.753	13.055	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	P06401	PGR	P24941	CDK2	S345	F339Y	339	Missense	distal	-6	no	13.491	13.487	EPSD	TCGA;ICGC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	P06401	PGR	P24941	CDK2	S350	A354T	354	Missense	distal	4	no	7.938	8.181	EPSD	TCGA;ICGC;COSMIC;GDSC;CCLE	8.148	Gain
CMGC_CDK_CDK2_CDK2_ST	P06401	PGR	P24941	CDK2	T351	A354T	354	Missense	distal	3	no	13.300	13.698	EPSD	TCGA;ICGC;COSMIC;GDSC;CCLE	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	P06401	PGR	P24941	CDK2	S400	A394V	394	Missense	distal	-6	no	15.850	15.853	EPSD;PhosphoSitePlus	TCGA;ICGC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	P06401	PGR	P24941	CDK2	S554	Q556H	556	Missense	proximal	2	no	13.084	13.103	EPSD	TCGA;ICGC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	P06401	PGR	P24941	CDK2	S554	S552N	552	Missense	proximal	-2	no	13.084	12.393	EPSD	TCGA;ICGC;COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	P06401	PGR	P24941	CDK2	S676	Q679E	679	Missense	distal	3	no	15.795	16.442	PhosphoSitePlus;EPSD	TCGA;ICGC;COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	P06401	PGR	P24941	CDK2	S676	L683F	683	Missense	distal	7	no	15.795	16.466	PhosphoSitePlus;EPSD	TCGA;ICGC;COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	P06401	PGR	P24941	CDK2	S676	R672T	672	Missense	distal	-4	no	15.795	16.204	PhosphoSitePlus;EPSD	TCGA;ICGC;COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	P06401	PGR	P24941	CDK2	S676	S676L	676	Missense	central	0	yes	15.795	0.000	PhosphoSitePlus;EPSD	TCGA;ICGC;COSMIC	8.148	Loss
CMGC_CDK_CDK2_CDK2_ST	P06401	PGR	P24941	CDK2	S676	Q679L	679	Missense	distal	3	no	15.795	15.436	PhosphoSitePlus;EPSD	TCGA	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	P06401	PGR	P24941	CDK2	S676	R672I	672	Missense	distal	-4	no	15.795	15.887	PhosphoSitePlus;EPSD	TCGA;ICGC;COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	P06401	PGR	P24941	CDK2	S676	P677T	677	Missense	proximal	1	no	15.795	5.837	PhosphoSitePlus;EPSD	TCGA;ICGC;COSMIC	8.148	Loss
CMGC_CDK_CDK2_CDK2_ST	O00571	DDX3X	P24941	CDK2	S76	G80R	80	Missense	distal	4	no	8.384	8.383	EPSD	TCGA;COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	O00571	DDX3X	P24941	CDK2	S78	G80R	80	Missense	proximal	2	no	8.786	8.827	EPSD	TCGA;COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	O00571	DDX3X	P24941	CDK2	S92	R99H	99	Missense	distal	7	no	9.795	9.437	EPSD	TCGA;COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	O00571	DDX3X	P24941	CDK2	S92	R99C	99	Missense	distal	7	no	9.795	9.947	EPSD	TCGA;COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	O00571	DDX3X	P24941	CDK2	S114	R121H	121	Missense	distal	7	no	10.774	10.415	EPSD	TCGA;COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	O00571	DDX3X	P24941	CDK2	S114	R113G	113	Missense	proximal	-1	no	10.774	11.252	EPSD	TCGA	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	O00571	DDX3X	P24941	CDK2	S114	R110C	110	Missense	distal	-4	no	10.774	10.265	EPSD	TCGA;COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	O00571	DDX3X	P24941	CDK2	S114	G108D	108	Missense	distal	-6	no	10.774	10.770	EPSD	TCGA;COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	O00571	DDX3X	P24941	CDK2	S125	R126P	126	Missense	proximal	1	no	0.862	10.660	EPSD	TCGA;COSMIC	8.148	Gain
CMGC_CDK_CDK2_CDK2_ST	O00571	DDX3X	P24941	CDK2	T204	V206L	206	Missense	proximal	2	no	12.380	12.150	PhosphoSitePlus	TCGA;COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	O00571	DDX3X	P24941	CDK2	T204	Y200S	200	Missense	distal	-4	no	12.380	12.269	PhosphoSitePlus	TCGA;COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	O00571	DDX3X	P24941	CDK2	T204	R199C	199	Missense	distal	-5	no	12.380	12.413	PhosphoSitePlus	TCGA;COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	O00571	DDX3X	P24941	CDK2	T204	K208N	208	Missense	distal	4	no	12.380	11.958	PhosphoSitePlus	TCGA;COSMIC;CCLE	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	O00571	DDX3X	P24941	CDK2	T204	R199P	199	Missense	distal	-5	no	12.380	12.333	PhosphoSitePlus	TCGA;COSMIC;CCLE	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	O00571	DDX3X	P24941	CDK2	T323	D329H	329	Missense	distal	6	no	15.023	15.033	EPSD	TCGA;ICGC;COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	O00571	DDX3X	P24941	CDK2	T323	R326H	326	Missense	distal	3	no	15.023	14.327	EPSD	TCGA;ICGC;COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	O00571	DDX3X	P24941	CDK2	S489	P493S	493	Missense	distal	4	no	8.315	8.328	EPSD	TCGA;ICGC;COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	O00571	DDX3X	P24941	CDK2	S492	P493S	493	Missense	proximal	1	no	12.554	1.288	EPSD	TCGA;ICGC;COSMIC	8.148	Loss
CMGC_CDK_CDK2_CDK2_ST	O00571	DDX3X	P24941	CDK2	S623	G625R	625	Missense	proximal	2	no	8.786	8.827	EPSD	TCGA;ICGC;COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	O00571	DDX3X	P24941	CDK2	S623	A618T	618	Missense	distal	-5	no	8.786	8.760	EPSD	TCGA;ICGC;COSMIC;CCLE	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	O00571	DDX3X	P24941	CDK2	S654	G649E	649	Missense	distal	-5	no	8.626	8.584	EPSD	TCGA;COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	O00571	DDX3X	P24941	CDK2	S654	D658H	658	Missense	distal	4	no	8.626	8.453	EPSD	TCGA	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	O00571	DDX3X	P24941	CDK2	S654	D658Y	658	Missense	distal	4	no	8.626	8.890	EPSD	TCGA;COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	Q9BXR0	QTRT1	P24941	CDK2	S139	E135D	135	Missense	distal	-4	no	17.548	17.844	PhosphoSitePlus	TCGA;ICGC;COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	Q9BXR0	QTRT1	P24941	CDK2	S139	E135K	135	Missense	distal	-4	no	17.548	17.236	PhosphoSitePlus	TCGA;ICGC;COSMIC;CCLE	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	Q9BXR0	QTRT1	P24941	CDK2	S139	N134S	134	Missense	distal	-5	no	17.548	17.484	PhosphoSitePlus	TCGA;ICGC;COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	Q9BXR0	QTRT1	P24941	CDK2	S139	E135G	135	Missense	distal	-4	no	17.548	16.999	PhosphoSitePlus	TCGA;ICGC;COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	Q9BXR0	QTRT1	P24941	CDK2	S139	E141D	141	Missense	proximal	2	no	17.548	17.448	PhosphoSitePlus	TCGA;ICGC;COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	Q9BXR0	QTRT1	P24941	CDK2	S139	S139N	139	Missense	central	0	yes	17.548	0.000	PhosphoSitePlus	TCGA;ICGC;COSMIC	8.148	Loss
CMGC_CDK_CDK2_CDK2_ST	P18858	LIG1	P24941	CDK2	S51	K54R	54	Missense	distal	3	no	16.386	15.397	EPSD;PhosphoSitePlus	TCGA;COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	P18858	LIG1	P24941	CDK2	S51	S47T	47	Missense	distal	-4	no	16.386	16.198	EPSD;PhosphoSitePlus	TCGA;COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	P18858	LIG1	P24941	CDK2	S51	P52L	52	Missense	proximal	1	no	16.386	6.565	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC;GDSC;CCLE	8.148	Loss
CMGC_CDK_CDK2_CDK2_ST	P18858	LIG1	P24941	CDK2	S51	P52S	52	Missense	proximal	1	no	16.386	5.120	EPSD;PhosphoSitePlus	TCGA;COSMIC;GDSC;CCLE	8.148	Loss
CMGC_CDK_CDK2_CDK2_ST	P18858	LIG1	P24941	CDK2	S76	K82N	82	Missense	distal	6	no	16.475	16.470	EPSD;PhosphoSitePlus	TCGA;COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	P18858	LIG1	P24941	CDK2	S109	D107N	107	Missense	proximal	-2	no	9.826	8.618	EPSD	TCGA;COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	P18858	LIG1	P24941	CDK2	S109	S116L	116	Missense	distal	7	no	9.826	10.008	EPSD	TCGA;COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	P18858	LIG1	P24941	CDK2	S109	P110S	110	Missense	proximal	1	no	9.826	-1.440	EPSD	TCGA;ICGC;COSMIC	8.148	Loss
CMGC_CDK_CDK2_CDK2_ST	P18858	LIG1	P24941	CDK2	S114	D107N	107	Missense	distal	-7	no	14.157	13.835	EPSD	TCGA;COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	P18858	LIG1	P24941	CDK2	S114	P119S	119	Missense	distal	5	no	14.157	14.056	EPSD	TCGA;ICGC;COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	P18858	LIG1	P24941	CDK2	S114	S116L	116	Missense	proximal	2	no	14.157	13.984	EPSD	TCGA;COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	P18858	LIG1	P24941	CDK2	S114	P110S	110	Missense	distal	-4	no	14.157	14.512	EPSD	TCGA;ICGC;COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	P18858	LIG1	P24941	CDK2	S114	R121H	121	Missense	distal	7	no	14.157	13.799	EPSD	TCGA;COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	P18858	LIG1	P24941	CDK2	T159	E153K	153	Missense	distal	-6	no	13.016	13.013	EPSD	TCGA;COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	P18858	LIG1	P24941	CDK2	T159	P160A	160	Missense	proximal	1	no	13.016	-1.387	EPSD	TCGA;COSMIC	8.148	Loss
CMGC_CDK_CDK2_CDK2_ST	P18858	LIG1	P24941	CDK2	T159	T159N	159	Missense	central	0	yes	13.016	0.000	EPSD	TCGA;COSMIC	8.148	Loss
CMGC_CDK_CDK2_CDK2_ST	P18858	LIG1	P24941	CDK2	T183	T183M	183	Missense	central	0	yes	16.795	0.000	EPSD	TCGA;COSMIC;GDSC	8.148	Loss
CMGC_CDK_CDK2_CDK2_ST	P18858	LIG1	P24941	CDK2	T195	E194D	194	Missense	proximal	-1	no	15.007	14.978	EPSD	TCGA;COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	P18858	LIG1	P24941	CDK2	T195	K192N	192	Missense	distal	-3	no	15.007	15.069	EPSD	TCGA;COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	P18858	LIG1	P24941	CDK2	T233	T227M	227	Missense	distal	-6	no	16.182	16.189	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	P18858	LIG1	P24941	CDK2	S323	P325S	325	Missense	proximal	2	no	14.421	14.487	EPSD	TCGA;COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	P18858	LIG1	P24941	CDK2	S323	R317C	317	Missense	distal	-6	no	14.421	14.424	EPSD	TCGA;COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	P18858	LIG1	P24941	CDK2	S323	A321T	321	Missense	proximal	-2	no	14.421	14.371	EPSD	TCGA;COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	P18858	LIG1	P24941	CDK2	S323	S323L	323	Missense	central	0	yes	14.421	0.000	EPSD	TCGA;COSMIC	8.148	Loss
CMGC_CDK_CDK2_CDK2_ST	P18858	LIG1	P24941	CDK2	S323	S318F	318	Missense	distal	-5	no	14.421	14.538	EPSD	TCGA;COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	P18858	LIG1	P24941	CDK2	S419	R413W	413	Missense	distal	-6	no	8.606	8.612	EPSD	TCGA;COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	P18858	LIG1	P24941	CDK2	S419	T420I	420	Missense	proximal	1	no	8.606	4.443	EPSD	TCGA;COSMIC	8.148	Loss
CMGC_CDK_CDK2_CDK2_ST	P18858	LIG1	P24941	CDK2	S419	A421S	421	Missense	proximal	2	no	8.606	8.648	EPSD	TCGA;COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	P18858	LIG1	P24941	CDK2	S801	G799D	799	Missense	proximal	-2	no	7.999	8.607	EPSD	TCGA;ICGC;COSMIC	8.148	Gain
CMGC_CDK_CDK2_CDK2_ST	P18858	LIG1	P24941	CDK2	S819	V816M	816	Missense	distal	-3	no	13.515	13.740	EPSD	TCGA;COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	P18858	LIG1	P24941	CDK2	S819	P822S	822	Missense	distal	3	no	13.515	13.549	EPSD	TCGA;COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	P18858	LIG1	P24941	CDK2	S819	A814V	814	Missense	distal	-5	no	13.515	13.521	EPSD	TCGA;COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	P18858	LIG1	P24941	CDK2	S901	R898Q	898	Missense	distal	-3	no	9.483	9.353	EPSD	TCGA;COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	P18858	LIG1	P24941	CDK2	S901	N905S	905	Missense	distal	4	no	9.483	9.517	EPSD	TCGA;COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	Q96KS0	EGLN2	P24941	CDK2	S74	R77Q	77	Missense	distal	3	no	17.052	15.309	EPSD	TCGA;ICGC;COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	Q96KS0	EGLN2	P24941	CDK2	S74	R77W	77	Missense	distal	3	no	17.052	14.412	EPSD	TCGA;ICGC;COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	Q96KS0	EGLN2	P24941	CDK2	S74	A68T	68	Missense	distal	-6	no	17.052	17.053	EPSD	TCGA;ICGC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	Q96KS0	EGLN2	P24941	CDK2	S130	R134Q	134	Missense	distal	4	no	15.587	15.769	PhosphoSitePlus	TCGA;ICGC;COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	Q96KS0	EGLN2	P24941	CDK2	S130	R134L	134	Missense	distal	4	no	15.587	15.820	PhosphoSitePlus	TCGA;ICGC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	Q96KS0	EGLN2	P24941	CDK2	S401	V400A	400	Missense	proximal	-1	no	8.517	8.290	EPSD	TCGA;COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	Q96KS0	EGLN2	P24941	CDK2	T405	V400A	400	Missense	distal	-5	no	9.169	9.163	EPSD	TCGA;COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	Q9H2G4	TSPYL2	P24941	CDK2	T340	R346W	346	Missense	distal	6	no	13.338	13.331	PhosphoSitePlus;EPSD	TCGA;ICGC;COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	Q9H2G4	TSPYL2	P24941	CDK2	T340	R343C	343	Missense	distal	3	no	13.338	6.974	PhosphoSitePlus;EPSD	TCGA;ICGC;COSMIC;CCLE	8.148	Loss
CMGC_CDK_CDK2_CDK2_ST	P15923	TCF3	P24941	CDK2	S102	A107T	107	Missense	distal	5	no	9.422	9.386	EPSD	TCGA;ICGC;COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	P15923	TCF3	P24941	CDK2	S102	R105Q	105	Missense	distal	3	no	9.422	7.678	EPSD	TCGA;ICGC;COSMIC	8.148	Loss
CMGC_CDK_CDK2_CDK2_ST	P15923	TCF3	P24941	CDK2	S134	S134N	134	Missense	central	0	yes	13.345	0.000	EPSD	TCGA;ICGC;COSMIC	8.148	Loss
CMGC_CDK_CDK2_CDK2_ST	P15923	TCF3	P24941	CDK2	S139	S134N	134	Missense	distal	-5	no	13.086	13.149	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	P15923	TCF3	P24941	CDK2	T205	P201S	201	Missense	distal	-4	no	14.417	14.772	EPSD	TCGA;ICGC;COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	P15923	TCF3	P24941	CDK2	T308	D315N	315	Missense	distal	7	no	16.249	15.469	EPSD	TCGA;ICGC;COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	P15923	TCF3	P24941	CDK2	S379	G376S	376	Missense	distal	-3	no	13.318	13.309	EPSD	TCGA;ICGC;COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	P15923	TCF3	P24941	CDK2	S514	E517K	517	Missense	distal	3	no	6.184	8.269	EPSD	TCGA;ICGC;COSMIC;GDSC	8.148	Gain
CMGC_CDK_CDK2_CDK2_ST	P15923	TCF3	P24941	CDK2	S529	P524S	524	Missense	distal	-5	no	13.756	13.712	EPSD	TCGA;ICGC;COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	P15923	TCF3	P24941	CDK2	S529	R525W	525	Missense	distal	-4	no	13.756	12.999	EPSD	TCGA;COSMIC;GDSC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	O60271	SPAG9	P24941	CDK2	S16	M20V	20	Missense	distal	4	no	7.567	8.215	EPSD	TCGA;ICGC	8.148	Gain
CMGC_CDK_CDK2_CDK2_ST	O60271	SPAG9	P24941	CDK2	S109	Q110P	110	Missense	proximal	1	no	6.061	13.973	EPSD	TCGA;ICGC;COSMIC	8.148	Gain
CMGC_CDK_CDK2_CDK2_ST	O60271	SPAG9	P24941	CDK2	S194	R200P	200	Missense	distal	6	no	8.954	8.970	EPSD	TCGA;ICGC;COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	O60271	SPAG9	P24941	CDK2	S194	R197T	197	Missense	distal	3	no	8.954	7.121	EPSD	TCGA;ICGC;COSMIC	8.148	Loss
CMGC_CDK_CDK2_CDK2_ST	O60271	SPAG9	P24941	CDK2	S194	R200H	200	Missense	distal	6	no	8.954	8.965	EPSD	TCGA;ICGC;COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	O60271	SPAG9	P24941	CDK2	T226	T226I	226	Missense	central	0	yes	12.761	0.000	EPSD	TCGA;ICGC;COSMIC	8.148	Loss
CMGC_CDK_CDK2_CDK2_ST	O60271	SPAG9	P24941	CDK2	S242	L246P	246	Missense	distal	4	no	10.039	9.927	EPSD	TCGA;ICGC;COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	O60271	SPAG9	P24941	CDK2	S245	L246P	246	Missense	proximal	1	no	2.607	12.428	EPSD	TCGA;ICGC;COSMIC	8.148	Gain
CMGC_CDK_CDK2_CDK2_ST	O60271	SPAG9	P24941	CDK2	S251	L246P	246	Missense	distal	-5	no	15.066	15.054	EPSD	TCGA;ICGC;COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	O60271	SPAG9	P24941	CDK2	T276	G271R	271	Missense	distal	-5	no	13.104	13.072	EPSD	TCGA;COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	O60271	SPAG9	P24941	CDK2	T292	P289L	289	Missense	distal	-3	no	16.757	16.686	EPSD	TCGA;COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	O60271	SPAG9	P24941	CDK2	T292	K295N	295	Missense	distal	3	no	16.757	13.487	EPSD	TCGA;COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	O60271	SPAG9	P24941	CDK2	T348	D352N	352	Missense	distal	4	no	10.726	10.771	EPSD	TCGA;COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	O60271	SPAG9	P24941	CDK2	S358	D352N	352	Missense	distal	-6	no	8.280	8.281	EPSD	TCGA;COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	O60271	SPAG9	P24941	CDK2	S381	D376H	376	Missense	distal	-5	no	8.336	8.325	EPSD	TCGA;COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	O60271	SPAG9	P24941	CDK2	S391	D398N	398	Missense	distal	7	no	8.660	7.880	EPSD	TCGA;COSMIC	8.148	Loss
CMGC_CDK_CDK2_CDK2_ST	O60271	SPAG9	P24941	CDK2	S932	S938I	938	Missense	distal	6	no	11.399	11.398	EPSD	TCGA	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	O60271	SPAG9	P24941	CDK2	S1262	S1268Y	1268	Missense	distal	6	no	9.764	9.754	EPSD	TCGA	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	O60271	SPAG9	P24941	CDK2	T1264	S1268Y	1268	Missense	distal	4	no	18.100	18.286	EPSD	TCGA	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	Q05516	ZBTB16	P24941	CDK2	S197	S190L	190	Missense	distal	-7	no	18.694	18.879	PhosphoSitePlus;EPSD	TCGA;ICGC;COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	Q05516	ZBTB16	P24941	CDK2	S197	L193I	193	Missense	distal	-4	no	18.694	18.601	PhosphoSitePlus;EPSD	TCGA;ICGC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	Q05516	ZBTB16	P24941	CDK2	S253	D255E	255	Missense	proximal	2	no	9.906	10.006	EPSD	TCGA;ICGC;COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	Q05516	ZBTB16	P24941	CDK2	S253	S253I	253	Missense	central	0	yes	9.906	0.000	EPSD	TCGA;ICGC	8.148	Loss
CMGC_CDK_CDK2_CDK2_ST	Q05516	ZBTB16	P24941	CDK2	S256	D255E	255	Missense	proximal	-1	no	13.701	13.731	EPSD	TCGA;ICGC;COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	Q05516	ZBTB16	P24941	CDK2	S256	S253I	253	Missense	distal	-3	no	13.701	13.626	EPSD	TCGA;ICGC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	Q05516	ZBTB16	P24941	CDK2	T282	E278Q	278	Missense	distal	-4	no	17.614	17.166	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	Q05516	ZBTB16	P24941	CDK2	T282	G281R	281	Missense	proximal	-1	no	17.614	17.136	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	Q05516	ZBTB16	P24941	CDK2	T282	V288I	288	Missense	distal	6	no	17.614	17.616	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	Q05516	ZBTB16	P24941	CDK2	T282	S287I	287	Missense	distal	5	no	17.614	17.808	EPSD;PhosphoSitePlus	TCGA;ICGC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	Q05516	ZBTB16	P24941	CDK2	T282	V288A	288	Missense	distal	6	no	17.614	17.612	EPSD;PhosphoSitePlus	TCGA;ICGC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	Q05516	ZBTB16	P24941	CDK2	T569	P573L	573	Missense	distal	4	no	9.340	9.452	EPSD	TCGA;ICGC;COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	Q05516	ZBTB16	P24941	CDK2	T569	E575K	575	Missense	distal	6	no	9.340	9.351	EPSD	TCGA;ICGC;COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	Q05516	ZBTB16	P24941	CDK2	T597	E603Q	603	Missense	distal	6	no	12.433	12.441	EPSD	TCGA;ICGC;COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	Q05516	ZBTB16	P24941	CDK2	T597	P601L	601	Missense	distal	4	no	12.433	12.545	EPSD	TCGA;ICGC;COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	Q05516	ZBTB16	P24941	CDK2	T597	T597P	597	Missense	central	0	yes	12.433	0.000	EPSD	TCGA;ICGC;COSMIC	8.148	Loss
CMGC_CDK_CDK2_CDK2_ST	Q05516	ZBTB16	P24941	CDK2	T597	H592Q	592	Missense	distal	-5	no	12.433	12.386	EPSD	TCGA;ICGC;COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	P29374	ARID4A	P24941	CDK2	T133	K138N	138	Missense	distal	5	no	12.701	12.858	EPSD	TCGA;ICGC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	P29374	ARID4A	P24941	CDK2	T133	T126S	126	Missense	distal	-7	no	12.701	12.523	EPSD	TCGA;ICGC;COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	P29374	ARID4A	P24941	CDK2	T151	E152K	152	Missense	proximal	1	no	9.616	1.132	EPSD	TCGA;ICGC;COSMIC	8.148	Loss
CMGC_CDK_CDK2_CDK2_ST	P29374	ARID4A	P24941	CDK2	T151	P149S	149	Missense	proximal	-2	no	9.616	8.965	EPSD	TCGA;ICGC;COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	P29374	ARID4A	P24941	CDK2	T498	D495Y	495	Missense	distal	-3	no	8.702	8.752	EPSD	TCGA;ICGC;COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	P29374	ARID4A	P24941	CDK2	T498	D497G	497	Missense	proximal	-1	no	8.702	8.995	EPSD	TCGA;ICGC;COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	P29374	ARID4A	P24941	CDK2	T555	E562K	562	Missense	distal	7	no	8.372	8.041	EPSD	TCGA;ICGC;COSMIC	8.148	Loss
CMGC_CDK_CDK2_CDK2_ST	P29374	ARID4A	P24941	CDK2	T555	K558R	558	Missense	distal	3	no	8.372	7.383	EPSD	TCGA;ICGC;COSMIC	8.148	Loss
CMGC_CDK_CDK2_CDK2_ST	P29374	ARID4A	P24941	CDK2	S698	E701K	701	Missense	distal	3	no	8.165	10.251	EPSD	TCGA;ICGC;COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	P29374	ARID4A	P24941	CDK2	S698	D699A	699	Missense	proximal	1	no	8.165	2.006	EPSD	TCGA;ICGC	8.148	Loss
CMGC_CDK_CDK2_CDK2_ST	P29374	ARID4A	P24941	CDK2	S789	E787K	787	Missense	proximal	-2	no	12.863	13.464	EPSD	TCGA;ICGC;COSMIC;CCLE	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	P29374	ARID4A	P24941	CDK2	S789	P790S	790	Missense	proximal	1	no	12.863	1.597	EPSD	TCGA;ICGC;COSMIC;CCLE	8.148	Loss
CMGC_CDK_CDK2_CDK2_ST	P29374	ARID4A	P24941	CDK2	S864	I869L	869	Missense	distal	5	no	20.135	20.083	PhosphoSitePlus;EPSD	TCGA;ICGC;COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	P29374	ARID4A	P24941	CDK2	S864	L860P	860	Missense	distal	-4	no	20.135	20.194	PhosphoSitePlus;EPSD	TCGA;ICGC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	P29374	ARID4A	P24941	CDK2	S864	R857W	857	Missense	distal	-7	no	20.135	20.306	PhosphoSitePlus;EPSD	TCGA;ICGC;COSMIC;GDSC;CCLE	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	P29374	ARID4A	P24941	CDK2	S882	M877I	877	Missense	distal	-5	no	9.849	9.781	EPSD	TCGA;ICGC;COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	P29374	ARID4A	P24941	CDK2	S882	S882C	882	Missense	central	0	yes	9.849	0.000	EPSD	TCGA;ICGC;COSMIC	8.148	Loss
CMGC_CDK_CDK2_CDK2_ST	P29374	ARID4A	P24941	CDK2	S882	V881I	881	Missense	proximal	-1	no	9.849	9.875	EPSD	TCGA;ICGC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	P29374	ARID4A	P24941	CDK2	S932	E936K	936	Missense	distal	4	no	15.539	15.924	EPSD	TCGA;ICGC;COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	P29374	ARID4A	P24941	CDK2	S932	R929I	929	Missense	distal	-3	no	15.539	15.370	EPSD	TCGA;ICGC;COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	P29374	ARID4A	P24941	CDK2	S932	T926A	926	Missense	distal	-6	no	15.539	15.538	EPSD	TCGA;ICGC;COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	P29374	ARID4A	P24941	CDK2	S1007	D1014G	1014	Missense	distal	7	no	11.761	11.744	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	P29374	ARID4A	P24941	CDK2	S1007	A1006S	1006	Missense	proximal	-1	no	11.761	11.560	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	P29374	ARID4A	P24941	CDK2	S1007	V1005A	1005	Missense	proximal	-2	no	11.761	12.426	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	P29374	ARID4A	P24941	CDK2	S1140	L1137P	1137	Missense	distal	-3	no	15.316	15.387	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	P29374	ARID4A	P24941	CDK2	S1140	P1146A	1146	Missense	distal	6	no	15.316	15.312	EPSD;PhosphoSitePlus	TCGA	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	P29374	ARID4A	P24941	CDK2	S1145	K1149N	1149	Missense	distal	4	no	15.244	14.822	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	P29374	ARID4A	P24941	CDK2	S1145	P1146A	1146	Missense	proximal	1	no	15.244	0.840	EPSD;PhosphoSitePlus	TCGA	8.148	Loss
CMGC_CDK_CDK2_CDK2_ST	P29374	ARID4A	P24941	CDK2	S1241	P1247S	1247	Missense	distal	6	no	16.262	16.263	EPSD	TCGA;COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	P29374	ARID4A	P24941	CDK2	S1246	P1247S	1247	Missense	proximal	1	no	14.757	3.491	EPSD	TCGA;COSMIC	8.148	Loss
CMGC_CDK_CDK2_CDK2_ST	P29374	ARID4A	P24941	CDK2	S1246	A1253T	1253	Missense	distal	7	no	14.757	14.068	EPSD	TCGA	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	Q5TZA2	CROCC	P24941	CDK2	S488	R485W	485	Missense	distal	-3	no	8.091	8.172	EPSD	TCGA;ICGC;COSMIC;GDSC;CCLE	8.148	Gain
CMGC_CDK_CDK2_CDK2_ST	Q5TZA2	CROCC	P24941	CDK2	T492	R485W	485	Missense	distal	-7	no	12.216	12.386	EPSD	TCGA;ICGC;COSMIC;GDSC;CCLE	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	Q5TZA2	CROCC	P24941	CDK2	T492	P495L	495	Missense	distal	3	no	12.216	11.832	EPSD	TCGA;ICGC;COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	Q5TZA2	CROCC	P24941	CDK2	T492	G489D	489	Missense	distal	-3	no	12.216	12.177	EPSD	TCGA;ICGC;COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	Q5TZA2	CROCC	P24941	CDK2	S494	P495L	495	Missense	proximal	1	no	15.424	5.603	EPSD	TCGA;ICGC;COSMIC	8.148	Loss
CMGC_CDK_CDK2_CDK2_ST	Q5TZA2	CROCC	P24941	CDK2	S494	G489D	489	Missense	distal	-5	no	15.424	15.402	EPSD	TCGA;ICGC;COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	Q5TZA2	CROCC	P24941	CDK2	S500	P495L	495	Missense	distal	-5	no	14.610	14.622	EPSD	TCGA;ICGC;COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	Q5TZA2	CROCC	P24941	CDK2	S500	R505C	505	Missense	distal	5	no	14.610	14.737	EPSD	TCGA;ICGC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	Q5TZA2	CROCC	P24941	CDK2	S506	S512F	512	Missense	distal	6	no	16.468	16.449	EPSD	TCGA;ICGC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	Q5TZA2	CROCC	P24941	CDK2	S506	R508H	508	Missense	proximal	2	no	16.468	16.387	EPSD	TCGA;ICGC;COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	Q5TZA2	CROCC	P24941	CDK2	S506	R505C	505	Missense	proximal	-1	no	16.468	15.771	EPSD	TCGA;ICGC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	Q5TZA2	CROCC	P24941	CDK2	S512	S512F	512	Missense	central	0	yes	10.715	0.000	EPSD	TCGA;ICGC	8.148	Loss
CMGC_CDK_CDK2_CDK2_ST	Q5TZA2	CROCC	P24941	CDK2	S512	R508H	508	Missense	distal	-4	no	10.715	10.354	EPSD	TCGA;ICGC;COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	Q5TZA2	CROCC	P24941	CDK2	S512	R505C	505	Missense	distal	-7	no	10.715	10.642	EPSD	TCGA;ICGC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	Q5TZA2	CROCC	P24941	CDK2	S516	S512F	512	Missense	distal	-4	no	8.749	7.787	EPSD	TCGA;ICGC	8.148	Loss
CMGC_CDK_CDK2_CDK2_ST	Q5TZA2	CROCC	P24941	CDK2	S516	A522T	522	Missense	distal	6	no	8.749	8.761	EPSD	TCGA;ICGC;COSMIC;CCLE	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	Q5TZA2	CROCC	P24941	CDK2	S602	A597T	597	Missense	distal	-5	no	8.174	8.148	EPSD	TCGA;ICGC;COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	Q5TZA2	CROCC	P24941	CDK2	S602	N598K	598	Missense	distal	-4	no	8.174	7.954	EPSD	TCGA;ICGC;COSMIC;GDSC	8.148	Loss
CMGC_CDK_CDK2_CDK2_ST	Q5TZA2	CROCC	P24941	CDK2	S602	S596R	596	Missense	distal	-6	no	8.174	8.177	EPSD	TCGA;ICGC;COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	Q5TZA2	CROCC	P24941	CDK2	S1490	P1493L	1493	Missense	distal	3	no	15.278	14.895	EPSD	TCGA;ICGC;COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	Q5TZA2	CROCC	P24941	CDK2	S1496	P1493L	1493	Missense	distal	-3	no	13.906	13.835	EPSD	TCGA;ICGC;COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	Q5TZA2	CROCC	P24941	CDK2	S1496	L1502P	1502	Missense	distal	6	no	13.906	13.905	EPSD	TCGA;ICGC;COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	Q5TZA2	CROCC	P24941	CDK2	S1499	L1502P	1502	Missense	distal	3	no	15.359	15.743	EPSD	TCGA;ICGC;COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	Q5TZA2	CROCC	P24941	CDK2	S1499	P1504L	1504	Missense	distal	5	no	15.359	15.399	EPSD	TCGA;ICGC;COSMIC;GDSC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	Q5TZA2	CROCC	P24941	CDK2	S1849	A1853T	1853	Missense	distal	4	no	8.402	8.644	EPSD	TCGA;ICGC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	Q5TZA2	CROCC	P24941	CDK2	T1911	D1907Y	1907	Missense	distal	-4	no	8.886	8.824	EPSD	TCGA;ICGC;COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	Q5TZA2	CROCC	P24941	CDK2	T1911	R1905H	1905	Missense	distal	-6	no	8.886	8.887	EPSD	TCGA;ICGC;COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	Q5TZA2	CROCC	P24941	CDK2	S2009	S2012F	2012	Missense	distal	3	no	16.642	16.567	EPSD	TCGA;ICGC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	Q5TZA2	CROCC	P24941	CDK2	S2009	E2016D	2016	Missense	distal	7	no	16.642	17.284	EPSD	TCGA;ICGC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	Q04637	EIF4G1	P24941	CDK2	S15	A22T	22	Missense	distal	7	no	12.202	11.514	EPSD	TCGA;ICGC;COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	Q04637	EIF4G1	P24941	CDK2	T43	S45Y	45	Missense	proximal	2	no	9.718	9.709	EPSD	TCGA;COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	Q04637	EIF4G1	P24941	CDK2	S134	G139S	139	Missense	distal	5	no	14.300	14.072	EPSD	TCGA	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	Q04637	EIF4G1	P24941	CDK2	S253	S260I	260	Missense	distal	7	no	11.891	12.100	EPSD	TCGA	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	Q04637	EIF4G1	P24941	CDK2	S261	S260I	260	Missense	proximal	-1	no	15.733	16.186	EPSD	TCGA	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	Q04637	EIF4G1	P24941	CDK2	S263	S267L	267	Missense	distal	4	no	12.604	12.702	EPSD	TCGA;COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	Q04637	EIF4G1	P24941	CDK2	S263	S260I	260	Missense	distal	-3	no	12.604	12.528	EPSD	TCGA	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	Q04637	EIF4G1	P24941	CDK2	T265	S267L	267	Missense	proximal	2	no	12.353	12.180	EPSD	TCGA;COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	Q04637	EIF4G1	P24941	CDK2	T265	S260I	260	Missense	distal	-5	no	12.353	12.437	EPSD	TCGA	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	Q04637	EIF4G1	P24941	CDK2	S267	S267L	267	Missense	central	0	yes	15.468	0.000	EPSD	TCGA;COSMIC	8.148	Loss
CMGC_CDK_CDK2_CDK2_ST	Q04637	EIF4G1	P24941	CDK2	S267	S260I	260	Missense	distal	-7	no	15.468	15.842	EPSD	TCGA	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	Q04637	EIF4G1	P24941	CDK2	S269	S267L	267	Missense	proximal	-2	no	12.274	12.701	EPSD	TCGA;COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	Q04637	EIF4G1	P24941	CDK2	S1101	G1096W	1096	Missense	distal	-5	no	10.860	10.915	EPSD	TCGA;COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	Q04637	EIF4G1	P24941	CDK2	T1179	R1173Q	1173	Missense	distal	-6	no	15.298	15.299	EPSD	TCGA	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	Q9ULX3	NOB1	P24941	CDK2	T210	G205W	205	Missense	distal	-5	no	13.370	13.425	EPSD	TCGA;ICGC;COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	Q9ULX3	NOB1	P24941	CDK2	S371	P372L	372	Missense	proximal	1	no	12.557	2.736	EPSD	TCGA;ICGC;COSMIC	8.148	Loss
CMGC_CDK_CDK2_CDK2_ST	Q9ULX3	NOB1	P24941	CDK2	S371	P364L	364	Missense	distal	-7	no	12.557	12.562	EPSD	TCGA;ICGC;COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	Q9NRH3	TUBG2	P24941	CDK2	T45	E43D	43	Missense	proximal	-2	no	10.767	11.748	EPSD	TCGA;ICGC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	Q9NRH3	TUBG2	P24941	CDK2	T45	A41T	41	Missense	distal	-4	no	10.767	10.992	EPSD	TCGA;ICGC;COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	Q9NRH3	TUBG2	P24941	CDK2	T45	V50I	50	Missense	distal	5	no	10.767	10.893	EPSD	TCGA;ICGC;COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	Q9NRH3	TUBG2	P24941	CDK2	T263	S259L	259	Missense	distal	-4	no	14.674	14.261	EPSD	TCGA;ICGC;COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	Q9NRH3	TUBG2	P24941	CDK2	T263	A258T	258	Missense	distal	-5	no	14.674	14.648	EPSD	TCGA;ICGC;COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	Q9NRH3	TUBG2	P24941	CDK2	T274	P275L	275	Missense	proximal	1	no	11.231	1.410	EPSD	TCGA;ICGC;COSMIC	8.148	Loss
CMGC_CDK_CDK2_CDK2_ST	Q9NRH3	TUBG2	P24941	CDK2	T274	T271I	271	Missense	distal	-3	no	11.231	11.290	EPSD	TCGA;ICGC;COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	Q9NRH3	TUBG2	P24941	CDK2	T274	Y273H	273	Missense	proximal	-1	no	11.231	10.911	EPSD	TCGA;ICGC;COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	Q9NRH3	TUBG2	P24941	CDK2	T274	G272S	272	Missense	proximal	-2	no	11.231	11.322	EPSD	TCGA;ICGC;COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	Q9NRH3	TUBG2	P24941	CDK2	S364	S369L	369	Missense	distal	5	no	10.936	11.077	EPSD	TCGA;ICGC;COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	Q9NRH3	TUBG2	P24941	CDK2	S364	H371N	371	Missense	distal	7	no	10.936	10.712	EPSD	TCGA;ICGC;COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	Q9NRH3	TUBG2	P24941	CDK2	S364	P368S	368	Missense	distal	4	no	10.936	10.950	EPSD	TCGA;ICGC;COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	Q16204	CCDC6	P24941	CDK2	S52	R55L	55	Missense	distal	3	no	13.550	11.448	EPSD	TCGA;ICGC;COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	Q16204	CCDC6	P24941	CDK2	S244	P243S	243	Missense	proximal	-1	no	14.569	14.098	PhosphoSitePlus	TCGA;ICGC;COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	Q16204	CCDC6	P24941	CDK2	S244	R246K	246	Missense	proximal	2	no	14.569	14.269	PhosphoSitePlus	TCGA;ICGC;COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	Q16204	CCDC6	P24941	CDK2	S254	M258V	258	Missense	distal	4	no	13.770	14.418	EPSD	TCGA;ICGC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	Q16204	CCDC6	P24941	CDK2	S352	R348H	348	Missense	distal	-4	no	14.177	13.816	EPSD	TCGA;ICGC;COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	Q16204	CCDC6	P24941	CDK2	S352	S359F	359	Missense	distal	7	no	14.177	15.031	EPSD	TCGA;ICGC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	Q16204	CCDC6	P24941	CDK2	S352	S359Y	359	Missense	distal	7	no	14.177	14.599	EPSD	TCGA;ICGC;COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	Q16204	CCDC6	P24941	CDK2	S352	S351Y	351	Missense	proximal	-1	no	14.177	15.087	EPSD	TCGA;ICGC;COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	Q16204	CCDC6	P24941	CDK2	S352	P358H	358	Missense	distal	6	no	14.177	14.172	EPSD	TCGA;ICGC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	Q16204	CCDC6	P24941	CDK2	T357	S359F	359	Missense	proximal	2	no	12.525	12.709	EPSD	TCGA;ICGC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	Q16204	CCDC6	P24941	CDK2	T357	S359Y	359	Missense	proximal	2	no	12.525	12.516	EPSD	TCGA;ICGC;COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	Q16204	CCDC6	P24941	CDK2	T357	P358H	358	Missense	proximal	1	no	12.525	5.766	EPSD	TCGA;ICGC	8.148	Loss
CMGC_CDK_CDK2_CDK2_ST	Q16204	CCDC6	P24941	CDK2	S359	S359F	359	Missense	central	0	yes	13.468	0.000	EPSD	TCGA;ICGC	8.148	Loss
CMGC_CDK_CDK2_CDK2_ST	Q16204	CCDC6	P24941	CDK2	S359	S359Y	359	Missense	central	0	yes	13.468	0.000	EPSD	TCGA;ICGC;COSMIC	8.148	Loss
CMGC_CDK_CDK2_CDK2_ST	Q16204	CCDC6	P24941	CDK2	S359	P365S	365	Missense	distal	6	no	13.468	13.469	EPSD	TCGA;ICGC;COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	Q16204	CCDC6	P24941	CDK2	S359	P358H	358	Missense	proximal	-1	no	13.468	13.587	EPSD	TCGA;ICGC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	Q16204	CCDC6	P24941	CDK2	S367	P365S	365	Missense	proximal	-2	no	12.166	11.515	EPSD	TCGA;ICGC;COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	Q16204	CCDC6	P24941	CDK2	S374	T380M	380	Missense	distal	6	no	8.544	8.518	EPSD	TCGA;ICGC;COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	Q16204	CCDC6	P24941	CDK2	T380	T380M	380	Missense	central	0	yes	14.298	0.000	EPSD	TCGA;ICGC;COSMIC	8.148	Loss
CMGC_CDK_CDK2_CDK2_ST	Q16204	CCDC6	P24941	CDK2	T380	T383A	383	Missense	distal	3	no	14.298	13.900	EPSD	TCGA;ICGC;COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	Q16204	CCDC6	P24941	CDK2	T380	R387I	387	Missense	distal	7	no	14.298	13.865	EPSD	TCGA;ICGC;COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	Q16204	CCDC6	P24941	CDK2	S395	N394Y	394	Missense	proximal	-1	no	13.293	13.805	EPSD	TCGA;ICGC;COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	Q16204	CCDC6	P24941	CDK2	S395	S395F	395	Missense	central	0	yes	13.293	0.000	EPSD	TCGA;ICGC;COSMIC	8.148	Loss
CMGC_CDK_CDK2_CDK2_ST	Q16204	CCDC6	P24941	CDK2	S413	I409M	409	Missense	distal	-4	no	13.460	12.862	EPSD	TCGA;ICGC;COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	Q16204	CCDC6	P24941	CDK2	S413	P412L	412	Missense	proximal	-1	no	13.460	13.280	EPSD	TCGA;ICGC;COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	Q16204	CCDC6	P24941	CDK2	S419	R425W	425	Missense	distal	6	no	16.162	16.154	EPSD	TCGA;ICGC;COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	Q16204	CCDC6	P24941	CDK2	S419	F423I	423	Missense	distal	4	no	16.162	16.316	EPSD	TCGA;ICGC;COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	Q16204	CCDC6	P24941	CDK2	S419	F423L	423	Missense	distal	4	no	16.162	16.456	EPSD	TCGA;COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	Q16204	CCDC6	P24941	CDK2	S419	P412L	412	Missense	distal	-7	no	16.162	16.167	EPSD	TCGA;ICGC;COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	Q16204	CCDC6	P24941	CDK2	T427	R425W	425	Missense	proximal	-2	no	10.712	10.213	EPSD	TCGA;ICGC;COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	Q16204	CCDC6	P24941	CDK2	T427	F423I	423	Missense	distal	-4	no	10.712	11.169	EPSD	TCGA;ICGC;COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	Q16204	CCDC6	P24941	CDK2	T427	F423L	423	Missense	distal	-4	no	10.712	11.262	EPSD	TCGA;COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	Q16204	CCDC6	P24941	CDK2	T427	T427M	427	Missense	central	0	yes	10.712	0.000	EPSD	TCGA;ICGC;COSMIC	8.148	Loss
CMGC_CDK_CDK2_CDK2_ST	Q16204	CCDC6	P24941	CDK2	S431	R425W	425	Missense	distal	-6	no	14.185	14.191	EPSD	TCGA;ICGC;COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	Q16204	CCDC6	P24941	CDK2	S431	T427M	427	Missense	distal	-4	no	14.185	13.270	EPSD	TCGA;ICGC;COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	Q16204	CCDC6	P24941	CDK2	T462	A468V	468	Missense	distal	6	no	12.911	12.914	EPSD	TCGA;ICGC;COSMIC;GDSC;CCLE	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	Q16204	CCDC6	P24941	CDK2	T462	H466P	466	Missense	distal	4	no	12.911	13.149	EPSD	TCGA;ICGC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	Q16204	CCDC6	P24941	CDK2	T462	H466Y	466	Missense	distal	4	no	12.911	13.348	EPSD	TCGA;ICGC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	Q12959	DLG1	P24941	CDK2	S102	E95Q	95	Missense	distal	-7	no	15.987	15.854	EPSD	TCGA;ICGC;COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	Q12959	DLG1	P24941	CDK2	S102	S100C	100	Missense	proximal	-2	no	15.987	15.576	EPSD	TCGA;ICGC;COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	Q12959	DLG1	P24941	CDK2	T115	D112N	112	Missense	distal	-3	no	14.720	14.676	EPSD	TCGA;ICGC;COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	Q12959	DLG1	P24941	CDK2	T115	P116L	116	Missense	proximal	1	no	14.720	4.899	EPSD	TCGA;ICGC;COSMIC	8.148	Loss
CMGC_CDK_CDK2_CDK2_ST	Q12959	DLG1	P24941	CDK2	T115	P116S	116	Missense	proximal	1	no	14.720	3.454	EPSD	TCGA;ICGC;COSMIC	8.148	Loss
CMGC_CDK_CDK2_CDK2_ST	Q12959	DLG1	P24941	CDK2	S122	P116S	116	Missense	distal	-6	no	11.137	11.136	EPSD	TCGA;ICGC;COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	Q12959	DLG1	P24941	CDK2	S158	A165S	165	Missense	distal	7	no	14.845	14.309	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	Q12959	DLG1	P24941	CDK2	T209	E208Q	208	Missense	proximal	-1	no	16.030	14.937	EPSD	TCGA;COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	Q12959	DLG1	P24941	CDK2	S432	D428H	428	Missense	distal	-4	no	11.350	10.219	EPSD	TCGA;COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	Q12959	DLG1	P24941	CDK2	S432	S432G	432	Missense	central	0	yes	11.350	0.000	EPSD	TCGA;COSMIC	8.148	Loss
CMGC_CDK_CDK2_CDK2_ST	Q12959	DLG1	P24941	CDK2	T440	A442V	442	Missense	proximal	2	no	11.846	11.944	EPSD	TCGA;COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	Q12959	DLG1	P24941	CDK2	S443	A442V	442	Missense	proximal	-1	no	15.997	16.224	PhosphoSitePlus;EPSD	TCGA;COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	Q12959	DLG1	P24941	CDK2	S448	A442V	442	Missense	distal	-6	no	13.899	13.902	EPSD	TCGA;COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	Q12959	DLG1	P24941	CDK2	S619	E622K	622	Missense	distal	3	no	6.295	8.380	EPSD	TCGA;COSMIC	8.148	Gain
CMGC_CDK_CDK2_CDK2_ST	Q86T82	USP37	P24941	CDK2	S2	G8V	8	Missense	distal	6	no	16.460	16.470	EPSD	TCGA;ICGC;COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	Q86T82	USP37	P24941	CDK2	S2	S2Y	2	Missense	central	0	yes	16.460	0.000	EPSD	TCGA;ICGC	8.148	Loss
CMGC_CDK_CDK2_CDK2_ST	Q86T82	USP37	P24941	CDK2	T191	S185C	185	Missense	distal	-6	no	14.525	14.531	EPSD	TCGA;ICGC;COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	Q86T82	USP37	P24941	CDK2	T191	L193V	193	Missense	proximal	2	no	14.525	14.754	EPSD	TCGA;ICGC;COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	Q86T82	USP37	P24941	CDK2	T295	S292L	292	Missense	distal	-3	no	11.264	11.098	EPSD	TCGA;ICGC;COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	Q86T82	USP37	P24941	CDK2	T295	R300T	300	Missense	distal	5	no	11.264	11.132	EPSD	TCGA;ICGC;COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	Q86T82	USP37	P24941	CDK2	T295	R300I	300	Missense	distal	5	no	11.264	11.250	EPSD	TCGA;ICGC;COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	Q86T82	USP37	P24941	CDK2	S462	S466L	466	Missense	distal	4	no	12.626	12.725	EPSD	TCGA;ICGC;COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	Q86T82	USP37	P24941	CDK2	S628	N623S	623	Missense	distal	-5	no	13.885	13.822	PhosphoSitePlus	TCGA	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	Q86T82	USP37	P24941	CDK2	S650	E653K	653	Missense	distal	3	no	7.248	9.334	EPSD	TCGA;ICGC;COSMIC	8.148	Gain
CMGC_CDK_CDK2_CDK2_ST	Q86T82	USP37	P24941	CDK2	T738	D744G	744	Missense	distal	6	no	10.268	10.272	EPSD	TCGA;ICGC;COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	Q86XL3	ANKLE2	P24941	CDK2	S235	R236Q	236	Missense	proximal	1	no	7.057	8.944	EPSD	TCGA;ICGC	8.148	Gain
CMGC_CDK_CDK2_CDK2_ST	Q86XL3	ANKLE2	P24941	CDK2	S259	T263A	263	Missense	distal	4	no	16.639	16.397	EPSD	TCGA;ICGC;COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	Q86XL3	ANKLE2	P24941	CDK2	S259	S259F	259	Missense	central	0	yes	16.639	0.000	EPSD	TCGA;ICGC	8.148	Loss
CMGC_CDK_CDK2_CDK2_ST	Q86XL3	ANKLE2	P24941	CDK2	S268	T263A	263	Missense	distal	-5	no	15.872	15.898	EPSD	TCGA;ICGC;COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	Q86XL3	ANKLE2	P24941	CDK2	S268	A273D	273	Missense	distal	5	no	15.872	16.036	EPSD	TCGA;ICGC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	Q86XL3	ANKLE2	P24941	CDK2	T406	K409N	409	Missense	distal	3	no	16.988	13.718	EPSD	TCGA;ICGC;COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	Q86XL3	ANKLE2	P24941	CDK2	T406	N405T	405	Missense	proximal	-1	no	16.988	16.798	EPSD	TCGA;ICGC;COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	Q86XL3	ANKLE2	P24941	CDK2	T406	Y412C	412	Missense	distal	6	no	16.988	16.982	EPSD	TCGA;ICGC;COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	Q86XL3	ANKLE2	P24941	CDK2	S488	S487F	487	Missense	proximal	-1	no	13.370	14.626	EPSD	TCGA;ICGC;COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	Q86XL3	ANKLE2	P24941	CDK2	S488	S487Y	487	Missense	proximal	-1	no	13.370	14.280	EPSD	TCGA;ICGC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	Q86XL3	ANKLE2	P24941	CDK2	S488	A483V	483	Missense	distal	-5	no	13.370	13.376	EPSD	TCGA;ICGC;COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	Q86XL3	ANKLE2	P24941	CDK2	S496	E502K	502	Missense	distal	6	no	16.120	16.131	EPSD	TCGA;ICGC;COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	Q86XL3	ANKLE2	P24941	CDK2	S512	R508H	508	Missense	distal	-4	no	12.853	12.492	EPSD	TCGA;ICGC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	Q86XL3	ANKLE2	P24941	CDK2	S528	D534N	534	Missense	distal	6	no	18.476	18.495	PhosphoSitePlus	TCGA;ICGC;COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	Q86XL3	ANKLE2	P24941	CDK2	S528	E533K	533	Missense	distal	5	no	18.476	18.343	PhosphoSitePlus	TCGA;ICGC;COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	Q86XL3	ANKLE2	P24941	CDK2	T541	R536C	536	Missense	distal	-5	no	15.373	15.407	EPSD	TCGA;ICGC;COSMIC;GDSC;CCLE	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	Q86XL3	ANKLE2	P24941	CDK2	T541	D534N	534	Missense	distal	-7	no	15.373	15.050	EPSD	TCGA;ICGC;COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	Q86XL3	ANKLE2	P24941	CDK2	T541	K537R	537	Missense	distal	-4	no	15.373	15.211	EPSD	TCGA;ICGC;COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	Q86XL3	ANKLE2	P24941	CDK2	T541	K537T	537	Missense	distal	-4	no	15.373	15.620	EPSD	TCGA;ICGC;COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	Q86XL3	ANKLE2	P24941	CDK2	S556	P558L	558	Missense	proximal	2	no	8.360	8.253	EPSD	TCGA;ICGC;COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	Q86XL3	ANKLE2	P24941	CDK2	S556	L550F	550	Missense	distal	-6	no	8.360	8.364	EPSD	TCGA;ICGC;COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	Q86XL3	ANKLE2	P24941	CDK2	S556	S556L	556	Missense	central	0	yes	8.360	0.000	EPSD	TCGA;ICGC;COSMIC;GDSC;CCLE	8.148	Loss
CMGC_CDK_CDK2_CDK2_ST	Q86XL3	ANKLE2	P24941	CDK2	S662	P663L	663	Missense	proximal	1	no	12.775	2.954	EPSD	TCGA;COSMIC	8.148	Loss
CMGC_CDK_CDK2_CDK2_ST	Q86XL3	ANKLE2	P24941	CDK2	T751	D753H	753	Missense	proximal	2	no	13.354	13.434	EPSD	TCGA;COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	Q86XL3	ANKLE2	P24941	CDK2	T751	R746C	746	Missense	distal	-5	no	13.354	13.388	EPSD	TCGA;COSMIC;GDSC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	Q86XL3	ANKLE2	P24941	CDK2	S778	D781N	781	Missense	distal	3	no	11.702	12.953	EPSD	TCGA;COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	Q86XL3	ANKLE2	P24941	CDK2	S778	R772T	772	Missense	distal	-6	no	11.702	11.700	EPSD	TCGA;COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	Q86XL3	ANKLE2	P24941	CDK2	S778	P777L	777	Missense	proximal	-1	no	11.702	11.523	EPSD	TCGA;COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	Q86XL3	ANKLE2	P24941	CDK2	S804	H810Q	810	Missense	distal	6	no	13.905	13.916	EPSD	TCGA;COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	Q86XL3	ANKLE2	P24941	CDK2	S804	P805S	805	Missense	proximal	1	no	13.905	2.639	EPSD	TCGA	8.148	Loss
CMGC_CDK_CDK2_CDK2_ST	Q86XL3	ANKLE2	P24941	CDK2	S804	L803F	803	Missense	proximal	-1	no	13.905	14.871	EPSD	TCGA;COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	Q86XL3	ANKLE2	P24941	CDK2	S807	H810Q	810	Missense	distal	3	no	13.820	12.773	EPSD	TCGA;COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	Q86XL3	ANKLE2	P24941	CDK2	S807	P805S	805	Missense	proximal	-2	no	13.820	13.168	EPSD	TCGA	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	Q86XL3	ANKLE2	P24941	CDK2	S807	L803F	803	Missense	distal	-4	no	13.820	13.270	EPSD	TCGA;COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	Q86XL3	ANKLE2	P24941	CDK2	S866	S868L	868	Missense	proximal	2	no	12.207	12.034	EPSD	TCGA;COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	Q86XL3	ANKLE2	P24941	CDK2	S875	S868L	868	Missense	distal	-7	no	12.543	12.728	EPSD	TCGA;COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	Q86XL3	ANKLE2	P24941	CDK2	S896	P897L	897	Missense	proximal	1	no	17.435	7.614	EPSD	TCGA;COSMIC	8.148	Loss
CMGC_CDK_CDK2_CDK2_ST	Q86XL3	ANKLE2	P24941	CDK2	S914	R917C	917	Missense	distal	3	no	17.338	10.974	EPSD	TCGA;COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	Q86XL3	ANKLE2	P24941	CDK2	S919	R917C	917	Missense	proximal	-2	no	15.932	16.106	EPSD	TCGA;COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	Q86XL3	ANKLE2	P24941	CDK2	S924	R917C	917	Missense	distal	-7	no	9.524	9.452	EPSD	TCGA;COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	Q86XL3	ANKLE2	P24941	CDK2	S924	R927C	927	Missense	distal	3	no	9.524	3.160	EPSD	TCGA;COSMIC	8.148	Loss
CMGC_CDK_CDK2_CDK2_ST	Q9UKY1	ZHX1	P24941	CDK2	S549	P550S	550	Missense	proximal	1	no	12.037	0.771	EPSD	TCGA;ICGC	8.148	Loss
CMGC_CDK_CDK2_CDK2_ST	Q9UKY1	ZHX1	P24941	CDK2	T568	P563L	563	Missense	distal	-5	no	16.490	16.502	PhosphoSitePlus	TCGA;ICGC;COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	Q9UKY1	ZHX1	P24941	CDK2	T568	F564C	564	Missense	distal	-4	no	16.490	16.346	PhosphoSitePlus	TCGA;ICGC;COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	Q9UKY1	ZHX1	P24941	CDK2	T568	E574G	574	Missense	distal	6	no	16.490	16.482	PhosphoSitePlus	TCGA;ICGC;COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	Q9UKY1	ZHX1	P24941	CDK2	S653	S660I	660	Missense	distal	7	no	8.774	8.983	EPSD	TCGA;ICGC;COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	Q9UKY1	ZHX1	P24941	CDK2	S686	R681L	681	Missense	distal	-5	no	15.776	15.741	EPSD	TCGA;ICGC;COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	Q9UKY1	ZHX1	P24941	CDK2	S686	K692E	692	Missense	distal	6	no	15.776	15.765	EPSD	TCGA;ICGC;COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	Q9UKY1	ZHX1	P24941	CDK2	S686	R681Q	681	Missense	distal	-5	no	15.776	15.729	EPSD	TCGA;ICGC;COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	Q9UKY1	ZHX1	P24941	CDK2	S774	L775F	775	Missense	proximal	1	no	8.270	3.281	EPSD	TCGA;ICGC;COSMIC	8.148	Loss
CMGC_CDK_CDK2_CDK2_ST	Q9UKY1	ZHX1	P24941	CDK2	S774	G772R	772	Missense	proximal	-2	no	8.270	7.777	EPSD	TCGA;ICGC	8.148	Loss
CMGC_CDK_CDK2_CDK2_ST	Q9UKY1	ZHX1	P24941	CDK2	S774	T780N	780	Missense	distal	6	no	8.270	8.267	EPSD	TCGA;ICGC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	P08621	SNRNP70	P24941	CDK2	S140	V135G	135	Missense	distal	-5	no	8.898	8.947	EPSD	TCGA;ICGC;COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	P08621	SNRNP70	P24941	CDK2	S140	S137G	137	Missense	distal	-3	no	8.898	8.907	EPSD	TCGA;ICGC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	P08621	SNRNP70	P24941	CDK2	S140	M134V	134	Missense	distal	-6	no	8.898	8.893	EPSD	TCGA;ICGC;COSMIC;CCLE	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	P08621	SNRNP70	P24941	CDK2	S140	R139W	139	Missense	proximal	-1	no	8.898	9.453	EPSD	TCGA;ICGC;COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	P08621	SNRNP70	P24941	CDK2	S226	P229L	229	Missense	distal	3	no	15.254	14.871	PhosphoSitePlus	TCGA;ICGC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	P08621	SNRNP70	P24941	CDK2	S226	D220N	220	Missense	distal	-6	no	15.254	15.255	PhosphoSitePlus	TCGA;ICGC;COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	P08621	SNRNP70	P24941	CDK2	S226	P227S	227	Missense	proximal	1	no	15.254	3.988	PhosphoSitePlus	TCGA;ICGC;COSMIC	8.148	Loss
CMGC_CDK_CDK2_CDK2_ST	P08621	SNRNP70	P24941	CDK2	S357	H358R	358	Missense	proximal	1	no	9.664	6.624	EPSD	TCGA	8.148	Loss
CMGC_CDK_CDK2_CDK2_ST	Q14676	MDC1	P24941	CDK2	S108	L115P	115	Missense	distal	7	no	13.497	13.466	EPSD	TCGA;ICGC;COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	Q14676	MDC1	P24941	CDK2	S108	R114H	114	Missense	distal	6	no	13.497	13.508	EPSD	TCGA;ICGC;COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	Q14676	MDC1	P24941	CDK2	S202	S202F	202	Missense	central	0	yes	13.551	0.000	EPSD	TCGA;ICGC;COSMIC	8.148	Loss
CMGC_CDK_CDK2_CDK2_ST	Q14676	MDC1	P24941	CDK2	S202	G206D	206	Missense	distal	4	no	13.551	13.606	EPSD	TCGA;ICGC;COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	Q14676	MDC1	P24941	CDK2	T341	P346S	346	Missense	distal	5	no	14.347	14.246	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	Q14676	MDC1	P24941	CDK2	S505	V499M	499	Missense	distal	-6	no	12.135	12.140	EPSD	TCGA;ICGC;COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	Q14676	MDC1	P24941	CDK2	S505	H509Y	509	Missense	distal	4	no	12.135	12.572	EPSD	TCGA;ICGC;COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	Q14676	MDC1	P24941	CDK2	T725	P727S	727	Missense	proximal	2	no	9.897	9.963	EPSD	TCGA;ICGC;COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	Q14676	MDC1	P24941	CDK2	T725	A721V	721	Missense	distal	-4	no	9.897	9.907	EPSD	TCGA;ICGC;COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	Q14676	MDC1	P24941	CDK2	S780	Y775C	775	Missense	distal	-5	no	15.760	15.817	EPSD	TCGA;ICGC;COSMIC;CCLE	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	Q14676	MDC1	P24941	CDK2	S793	E792D	792	Missense	proximal	-1	no	17.286	17.256	EPSD	TCGA;ICGC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	Q14676	MDC1	P24941	CDK2	S882	D875H	875	Missense	distal	-7	no	14.584	14.466	EPSD	TCGA;ICGC;COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	Q14676	MDC1	P24941	CDK2	S882	E879Q	879	Missense	distal	-3	no	14.584	14.468	EPSD	TCGA;ICGC;COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	Q14676	MDC1	P24941	CDK2	S964	S964N	964	Missense	central	0	yes	12.779	0.000	EPSD	TCGA;ICGC	8.148	Loss
CMGC_CDK_CDK2_CDK2_ST	Q14676	MDC1	P24941	CDK2	T966	S964N	964	Missense	proximal	-2	no	10.668	9.976	EPSD	TCGA;ICGC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	Q14676	MDC1	P24941	CDK2	T966	A973V	973	Missense	distal	7	no	10.668	10.541	EPSD	TCGA;ICGC;CCLE	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	Q14676	MDC1	P24941	CDK2	S990	G992V	992	Missense	proximal	2	no	10.018	10.023	EPSD	TCGA;ICGC;COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	Q14676	MDC1	P24941	CDK2	S995	G992V	992	Missense	distal	-3	no	12.126	12.166	EPSD	TCGA;ICGC;COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	Q14676	MDC1	P24941	CDK2	S998	G992V	992	Missense	distal	-6	no	17.115	17.114	EPSD	TCGA;ICGC;COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	Q14676	MDC1	P24941	CDK2	S1033	L1038V	1038	Missense	distal	5	no	10.643	10.570	EPSD	TCGA;COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	Q14676	MDC1	P24941	CDK2	S1033	D1030N	1030	Missense	distal	-3	no	10.643	10.599	EPSD	TCGA	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	Q14676	MDC1	P24941	CDK2	S1033	D1035A	1035	Missense	proximal	2	no	10.643	10.670	EPSD	TCGA;COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	Q14676	MDC1	P24941	CDK2	S1068	P1065L	1065	Missense	distal	-3	no	13.716	13.645	EPSD;PhosphoSitePlus	TCGA;COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	Q14676	MDC1	P24941	CDK2	S1086	Q1087H	1087	Missense	proximal	1	no	7.020	8.173	EPSD	TCGA;COSMIC	8.148	Gain
CMGC_CDK_CDK2_CDK2_ST	Q14676	MDC1	P24941	CDK2	T1116	R1110Q	1110	Missense	distal	-6	no	13.217	13.218	EPSD	TCGA;COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	Q14676	MDC1	P24941	CDK2	T1138	P1139S	1139	Missense	proximal	1	no	13.128	1.863	EPSD	TCGA;COSMIC	8.148	Loss
CMGC_CDK_CDK2_CDK2_ST	Q14676	MDC1	P24941	CDK2	T1138	S1132C	1132	Missense	distal	-6	no	13.128	13.135	EPSD	TCGA;COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	Q14676	MDC1	P24941	CDK2	T1138	S1143Y	1143	Missense	distal	5	no	13.128	13.303	EPSD	TCGA	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	Q14676	MDC1	P24941	CDK2	T1198	S1194C	1194	Missense	distal	-4	no	12.162	11.056	EPSD	TCGA;ICGC;COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	Q14676	MDC1	P24941	CDK2	T1239	K1232N	1232	Missense	distal	-7	no	12.488	12.453	EPSD	TCGA;COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	Q14676	MDC1	P24941	CDK2	T1280	P1286L	1286	Missense	distal	6	no	12.563	12.564	EPSD	TCGA	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	Q14676	MDC1	P24941	CDK2	T1302	R1308Q	1308	Missense	distal	6	no	12.215	12.236	EPSD	TCGA;COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	Q14676	MDC1	P24941	CDK2	T1321	T1328I	1328	Missense	distal	7	no	11.941	12.302	EPSD	TCGA;COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	Q14676	MDC1	P24941	CDK2	T1321	T1321I	1321	Missense	central	0	yes	11.941	0.000	EPSD	TCGA;COSMIC	8.148	Loss
CMGC_CDK_CDK2_CDK2_ST	Q14676	MDC1	P24941	CDK2	T1343	P1344T	1344	Missense	proximal	1	no	12.135	2.178	EPSD	TCGA;COSMIC	8.148	Loss
CMGC_CDK_CDK2_CDK2_ST	Q14676	MDC1	P24941	CDK2	T1343	T1347I	1347	Missense	distal	4	no	12.135	11.824	EPSD	TCGA;COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	Q14676	MDC1	P24941	CDK2	T1384	R1390W	1390	Missense	distal	6	no	13.621	13.614	EPSD	TCGA;COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	Q14676	MDC1	P24941	CDK2	T1384	R1390Q	1390	Missense	distal	6	no	13.621	13.643	EPSD	TCGA;COSMIC;GDSC;CCLE	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	Q14676	MDC1	P24941	CDK2	T1384	S1389Y	1389	Missense	distal	5	no	13.621	13.796	EPSD	TCGA;COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	Q14676	MDC1	P24941	CDK2	T1403	N1397I	1397	Missense	distal	-6	no	12.170	12.173	EPSD	TCGA;COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	Q14676	MDC1	P24941	CDK2	T1403	N1397H	1397	Missense	distal	-6	no	12.170	12.174	EPSD	TCGA;COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	Q14676	MDC1	P24941	CDK2	T1425	P1426H	1426	Missense	proximal	1	no	13.449	6.691	EPSD	TCGA;COSMIC	8.148	Loss
CMGC_CDK_CDK2_CDK2_ST	Q14676	MDC1	P24941	CDK2	T1425	S1430C	1430	Missense	distal	5	no	13.449	13.784	EPSD	TCGA;COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	Q14676	MDC1	P24941	CDK2	T1425	T1425A	1425	Missense	central	0	yes	13.449	0.000	EPSD	TCGA;COSMIC	8.148	Loss
CMGC_CDK_CDK2_CDK2_ST	Q14676	MDC1	P24941	CDK2	T1444	T1451A	1451	Missense	distal	7	no	12.119	12.807	EPSD	TCGA;COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	Q14676	MDC1	P24941	CDK2	T1444	S1440F	1440	Missense	distal	-4	no	12.119	11.156	EPSD	TCGA;COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	Q14676	MDC1	P24941	CDK2	T1466	P1469H	1469	Missense	distal	3	no	13.903	14.925	EPSD	TCGA;COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	Q14676	MDC1	P24941	CDK2	T1466	D1462E	1462	Missense	distal	-4	no	13.903	13.607	EPSD	TCGA;COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	Q14676	MDC1	P24941	CDK2	T1466	T1459I	1459	Missense	distal	-7	no	13.903	14.100	EPSD	TCGA;COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	Q14676	MDC1	P24941	CDK2	T1485	R1480I	1480	Missense	distal	-5	no	11.926	11.918	EPSD	TCGA	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	Q14676	MDC1	P24941	CDK2	T1485	R1480K	1480	Missense	distal	-5	no	11.926	11.882	EPSD	TCGA;COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	Q14676	MDC1	P24941	CDK2	T1526	R1521Q	1521	Missense	distal	-5	no	12.329	12.283	EPSD	TCGA;COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	Q14676	MDC1	P24941	CDK2	T1526	A1533T	1533	Missense	distal	7	no	12.329	11.641	EPSD	TCGA;COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	Q14676	MDC1	P24941	CDK2	T1548	S1553F	1553	Missense	distal	5	no	13.319	13.638	EPSD	TCGA;COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	Q14676	MDC1	P24941	CDK2	T1567	R1562K	1562	Missense	distal	-5	no	12.663	12.619	EPSD	TCGA;COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	Q14676	MDC1	P24941	CDK2	T1567	K1566N	1566	Missense	proximal	-1	no	12.663	12.690	EPSD	TCGA	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	Q14676	MDC1	P24941	CDK2	T1589	R1595W	1595	Missense	distal	6	no	12.947	12.939	EPSD	TCGA;COSMIC;GDSC;CCLE	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	Q14676	MDC1	P24941	CDK2	T1608	S1605C	1605	Missense	distal	-3	no	11.373	11.380	EPSD	TCGA;COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	Q14676	MDC1	P24941	CDK2	T1608	V1606F	1606	Missense	proximal	-2	no	11.373	10.909	EPSD	TCGA	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	Q14676	MDC1	P24941	CDK2	T1608	R1603W	1603	Missense	distal	-5	no	11.373	11.460	EPSD	TCGA;COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	Q14676	MDC1	P24941	CDK2	T1630	T1634I	1634	Missense	distal	4	no	12.643	12.331	PhosphoSitePlus;EPSD	TCGA;COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	Q14676	MDC1	P24941	CDK2	T1649	S1646F	1646	Missense	distal	-3	no	11.947	12.039	EPSD	TCGA;COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	Q14676	MDC1	P24941	CDK2	T1649	R1644M	1644	Missense	distal	-5	no	11.947	12.008	EPSD	TCGA;COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	Q14676	MDC1	P24941	CDK2	T1664	L1660F	1660	Missense	distal	-4	no	12.247	11.698	EPSD	TCGA;COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	Q14676	MDC1	P24941	CDK2	T1664	S1658F	1658	Missense	distal	-6	no	12.247	12.252	EPSD	TCGA	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	Q14676	MDC1	P24941	CDK2	T1664	V1670I	1670	Missense	distal	6	no	12.247	12.249	EPSD	TCGA;COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	Q14676	MDC1	P24941	CDK2	T1671	Q1677E	1677	Missense	distal	6	no	14.663	14.654	EPSD	TCGA;COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	Q14676	MDC1	P24941	CDK2	T1671	V1670I	1670	Missense	proximal	-1	no	14.663	14.689	EPSD	TCGA;COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	Q14676	MDC1	P24941	CDK2	T1697	E1699A	1699	Missense	proximal	2	no	14.653	14.581	EPSD	TCGA	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	Q14676	MDC1	P24941	CDK2	T1697	E1699Q	1699	Missense	proximal	2	no	14.653	14.615	EPSD	TCGA;COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	Q14676	MDC1	P24941	CDK2	T1697	P1703S	1703	Missense	distal	6	no	14.653	14.654	EPSD	TCGA;COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	Q14676	MDC1	P24941	CDK2	S1702	E1699A	1699	Missense	distal	-3	no	11.919	11.686	EPSD	TCGA	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	Q14676	MDC1	P24941	CDK2	S1702	E1699Q	1699	Missense	distal	-3	no	11.919	11.802	EPSD	TCGA;COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	Q14676	MDC1	P24941	CDK2	S1702	P1703S	1703	Missense	proximal	1	no	11.919	0.653	EPSD	TCGA;COSMIC	8.148	Loss
CMGC_CDK_CDK2_CDK2_ST	Q14676	MDC1	P24941	CDK2	S1711	I1710F	1710	Missense	proximal	-1	no	13.926	14.729	EPSD	TCGA;ICGC;COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	Q14676	MDC1	P24941	CDK2	S1711	S1711F	1711	Missense	central	0	yes	13.926	0.000	EPSD	TCGA;ICGC;COSMIC	8.148	Loss
CMGC_CDK_CDK2_CDK2_ST	Q14676	MDC1	P24941	CDK2	S1775	L1778R	1778	Missense	distal	3	no	14.242	16.344	EPSD	TCGA;ICGC;COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	Q14676	MDC1	P24941	CDK2	T1781	H1784Y	1784	Missense	distal	3	no	12.270	10.503	EPSD	TCGA;COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	Q14676	MDC1	P24941	CDK2	T1781	L1778R	1778	Missense	distal	-3	no	12.270	12.530	EPSD	TCGA;ICGC;COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	Q14676	MDC1	P24941	CDK2	T1800	P1805H	1805	Missense	distal	5	no	11.916	11.994	EPSD	TCGA;COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	Q14676	MDC1	P24941	CDK2	T1800	F1799L	1799	Missense	proximal	-1	no	11.916	10.951	EPSD	TCGA;ICGC;COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	Q14676	MDC1	P24941	CDK2	S1810	R1811H	1811	Missense	proximal	1	no	5.748	8.788	EPSD	TCGA;ICGC;COSMIC	8.148	Gain
CMGC_CDK_CDK2_CDK2_ST	Q14676	MDC1	P24941	CDK2	S1820	S1820L	1820	Missense	central	0	yes	11.067	0.000	EPSD	TCGA;ICGC;COSMIC	8.148	Loss
CMGC_CDK_CDK2_CDK2_ST	Q14676	MDC1	P24941	CDK2	S1820	M1818V	1818	Missense	proximal	-2	no	11.067	12.502	EPSD	TCGA;ICGC;COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	Q14676	MDC1	P24941	CDK2	S1820	P1827S	1827	Missense	distal	7	no	11.067	10.915	EPSD	TCGA;COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	Q14676	MDC1	P24941	CDK2	T1858	V1857M	1857	Missense	proximal	-1	no	12.923	14.016	EPSD	TCGA;ICGC;COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	Q14676	MDC1	P24941	CDK2	T1858	D1855Y	1855	Missense	distal	-3	no	12.923	12.973	EPSD	TCGA;ICGC;COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	Q14676	MDC1	P24941	CDK2	T1858	T1858I	1858	Missense	central	0	yes	12.923	0.000	EPSD	TCGA;ICGC;COSMIC	8.148	Loss
CMGC_CDK_CDK2_CDK2_ST	Q8WXE1	ATRIP	P24941	CDK2	S224	S230F	230	Missense	distal	6	no	15.669	15.650	PhosphoSitePlus	TCGA;ICGC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	P50613	CDK7	P24941	CDK2	T110	N105T	105	Missense	distal	-5	no	13.509	13.488	EPSD	TCGA;COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	P50613	CDK7	P24941	CDK2	T110	K115N	115	Missense	distal	5	no	13.509	13.666	EPSD	TCGA	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	P50613	CDK7	P24941	CDK2	S112	N105T	105	Missense	distal	-7	no	11.467	11.546	EPSD	TCGA;COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	P50613	CDK7	P24941	CDK2	S112	K115N	115	Missense	distal	3	no	11.467	8.197	EPSD	TCGA	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	P50613	CDK7	P24941	CDK2	S164	A159T	159	Missense	distal	-5	no	20.404	20.378	EPSD;PhosphoSitePlus	TCGA;COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	P50613	CDK7	P24941	CDK2	S164	P165R	165	Missense	proximal	1	no	20.404	10.605	EPSD;PhosphoSitePlus	TCGA;COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	P50613	CDK7	P24941	CDK2	S164	N166D	166	Missense	proximal	2	no	20.404	20.471	EPSD;PhosphoSitePlus	TCGA;COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	P50613	CDK7	P24941	CDK2	T170	P165R	165	Missense	distal	-5	no	14.179	14.226	PhosphoSitePlus;EPSD	TCGA;COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	P50613	CDK7	P24941	CDK2	T170	N166D	166	Missense	distal	-4	no	14.179	14.568	PhosphoSitePlus;EPSD	TCGA;COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	P50613	CDK7	P24941	CDK2	S217	D220H	220	Missense	distal	3	no	5.542	8.378	EPSD	TCGA;COSMIC	8.148	Gain
CMGC_CDK_CDK2_CDK2_ST	P50613	CDK7	P24941	CDK2	T231	E234K	234	Missense	distal	3	no	13.735	15.821	EPSD	TCGA;COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	P06748	NPM1	P24941	CDK2	S10	D3Y	3	Missense	distal	-7	no	16.787	16.671	EPSD	TCGA	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	P06748	NPM1	P24941	CDK2	S10	L12M	12	Missense	proximal	2	no	16.787	17.105	EPSD	TCGA;ICGC;COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	P06748	NPM1	P24941	CDK2	S10	S4L	4	Missense	distal	-6	no	16.787	16.788	EPSD	TCGA;ICGC;COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	P06748	NPM1	P24941	CDK2	S70	K73Q	73	Missense	distal	3	no	19.803	17.070	PhosphoSitePlus;EPSD	TCGA;ICGC;COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	P06748	NPM1	P24941	CDK2	T95	E93K	93	Missense	proximal	-2	no	14.238	14.839	EPSD	TCGA;ICGC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	P06748	NPM1	P24941	CDK2	S106	S106L	106	Missense	central	0	yes	9.382	0.000	EPSD	TCGA;ICGC;COSMIC	8.148	Loss
CMGC_CDK_CDK2_CDK2_ST	P06748	NPM1	P24941	CDK2	T199	I196V	196	Missense	distal	-3	no	16.152	16.275	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	P06748	NPM1	P24941	CDK2	T219	D213N	213	Missense	distal	-6	no	13.177	13.179	EPSD	TCGA;ICGC;COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	P06748	NPM1	P24941	CDK2	T219	P216S	216	Missense	distal	-3	no	13.177	13.273	EPSD	TCGA;ICGC;COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	P06748	NPM1	P24941	CDK2	T234	K239N	239	Missense	distal	5	no	11.174	11.331	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	P06748	NPM1	P24941	CDK2	T237	K239N	239	Missense	proximal	2	no	11.064	11.135	EPSD	TCGA;ICGC;COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	Q9BZL4	PPP1R12C	P24941	CDK2	S325	R328W	328	Missense	distal	3	no	8.432	5.792	EPSD	TCGA;ICGC;COSMIC	8.148	Loss
CMGC_CDK_CDK2_CDK2_ST	Q9BZL4	PPP1R12C	P24941	CDK2	S325	R319W	319	Missense	distal	-6	no	8.432	8.438	EPSD	TCGA;ICGC;COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	Q9BZL4	PPP1R12C	P24941	CDK2	S399	K406E	406	Missense	distal	7	no	15.462	15.793	EPSD	TCGA;ICGC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	Q9BZL4	PPP1R12C	P24941	CDK2	S399	P400S	400	Missense	proximal	1	no	15.462	4.196	EPSD	TCGA;ICGC;COSMIC	8.148	Loss
CMGC_CDK_CDK2_CDK2_ST	Q9BZL4	PPP1R12C	P24941	CDK2	S399	V397I	397	Missense	proximal	-2	no	15.462	15.958	EPSD	TCGA;ICGC;COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	Q9BZL4	PPP1R12C	P24941	CDK2	S404	K406E	406	Missense	proximal	2	no	11.770	12.008	EPSD	TCGA;ICGC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	Q9BZL4	PPP1R12C	P24941	CDK2	S404	P400S	400	Missense	distal	-4	no	11.770	12.125	EPSD	TCGA;ICGC;COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	Q9BZL4	PPP1R12C	P24941	CDK2	S404	V397I	397	Missense	distal	-7	no	11.770	11.945	EPSD	TCGA;ICGC;COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	Q9BZL4	PPP1R12C	P24941	CDK2	S404	V409M	409	Missense	distal	5	no	11.770	12.111	EPSD	TCGA;ICGC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	Q9BZL4	PPP1R12C	P24941	CDK2	S407	K406E	406	Missense	proximal	-1	no	15.378	16.263	EPSD	TCGA;ICGC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	Q9BZL4	PPP1R12C	P24941	CDK2	S407	P400S	400	Missense	distal	-7	no	15.378	15.198	EPSD	TCGA;ICGC;COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	Q9BZL4	PPP1R12C	P24941	CDK2	S407	V409M	409	Missense	proximal	2	no	15.378	15.466	EPSD	TCGA;ICGC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	Q9BZL4	PPP1R12C	P24941	CDK2	T472	P473L	473	Missense	proximal	1	no	11.320	1.499	EPSD	TCGA;ICGC;COSMIC	8.148	Loss
CMGC_CDK_CDK2_CDK2_ST	Q9BZL4	PPP1R12C	P24941	CDK2	T472	E465D	465	Missense	distal	-7	no	11.320	11.471	EPSD	TCGA;ICGC;COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	Q9BZL4	PPP1R12C	P24941	CDK2	T472	R470I	470	Missense	proximal	-2	no	11.320	12.402	EPSD	TCGA;ICGC;COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	Q9BZL4	PPP1R12C	P24941	CDK2	T474	P473L	473	Missense	proximal	-1	no	14.682	14.503	EPSD	TCGA;ICGC;COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	Q9BZL4	PPP1R12C	P24941	CDK2	T474	R470I	470	Missense	distal	-4	no	14.682	14.774	EPSD	TCGA;ICGC;COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	Q9BZL4	PPP1R12C	P24941	CDK2	S476	P473L	473	Missense	distal	-3	no	12.262	12.191	EPSD	TCGA;ICGC;COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	Q9BZL4	PPP1R12C	P24941	CDK2	S499	P505L	505	Missense	distal	6	no	11.988	11.990	EPSD	TCGA;ICGC;COSMIC;GDSC;CCLE	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	Q9BZL4	PPP1R12C	P24941	CDK2	S499	P505A	505	Missense	distal	6	no	11.988	11.984	EPSD	TCGA;ICGC;COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	Q9BZL4	PPP1R12C	P24941	CDK2	S499	E496D	496	Missense	distal	-3	no	11.988	11.879	EPSD	TCGA;ICGC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	Q9BZL4	PPP1R12C	P24941	CDK2	S509	P507L	507	Missense	proximal	-2	no	18.481	18.256	PhosphoSitePlus	TCGA	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	Q9BZL4	PPP1R12C	P24941	CDK2	S509	P505L	505	Missense	distal	-4	no	18.481	18.422	PhosphoSitePlus	TCGA;ICGC;COSMIC;GDSC;CCLE	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	Q9BZL4	PPP1R12C	P24941	CDK2	S509	P505A	505	Missense	distal	-4	no	18.481	18.422	PhosphoSitePlus	TCGA;ICGC;COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	Q9BZL4	PPP1R12C	P24941	CDK2	S526	R527Q	527	Missense	proximal	1	no	7.975	9.862	EPSD	TCGA;ICGC	8.148	Gain
CMGC_CDK_CDK2_CDK2_ST	Q9BZL4	PPP1R12C	P24941	CDK2	S544	R538W	538	Missense	distal	-6	no	9.059	9.065	EPSD	TCGA;ICGC;COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	Q9BZL4	PPP1R12C	P24941	CDK2	S544	D539G	539	Missense	distal	-5	no	9.059	9.081	EPSD	TCGA;ICGC;COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	Q9BZL4	PPP1R12C	P24941	CDK2	S544	R549H	549	Missense	distal	5	no	9.059	9.031	EPSD	TCGA;ICGC;COSMIC;GDSC;CCLE	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	Q9BZL4	PPP1R12C	P24941	CDK2	T560	Q561P	561	Missense	proximal	1	no	5.124	13.035	EPSD	TCGA;ICGC;COSMIC	8.148	Gain
CMGC_CDK_CDK2_CDK2_ST	Q9BZL4	PPP1R12C	P24941	CDK2	T564	L565P	565	Missense	proximal	1	no	-0.649	9.171	EPSD	TCGA;ICGC;COSMIC	8.148	Gain
CMGC_CDK_CDK2_CDK2_ST	Q9BZL4	PPP1R12C	P24941	CDK2	S604	S602T	602	Missense	proximal	-2	no	14.955	15.573	EPSD	TCGA;ICGC;COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	Q9BZL4	PPP1R12C	P24941	CDK2	S604	R608K	608	Missense	distal	4	no	14.955	15.477	EPSD	TCGA;ICGC;COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	Q9BZL4	PPP1R12C	P24941	CDK2	S604	S604I	604	Missense	central	0	yes	14.955	0.000	EPSD	TCGA;ICGC	8.148	Loss
CMGC_CDK_CDK2_CDK2_ST	Q14194	CRMP1	P24941	CDK2	T509	P510S	510	Missense	proximal	1	no	12.420	1.154	PhosphoSitePlus	TCGA	8.148	Loss
CMGC_CDK_CDK2_CDK2_ST	Q14194	CRMP1	P24941	CDK2	T514	P510S	510	Missense	distal	-4	no	12.114	12.468	EPSD	TCGA	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	Q13416	ORC2	P24941	CDK2	T116	K119N	119	Missense	distal	3	no	15.988	12.718	PhosphoSitePlus;EPSD	TCGA;ICGC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	Q13416	ORC2	P24941	CDK2	S280	S277I	277	Missense	distal	-3	no	14.755	14.680	EPSD	TCGA;ICGC;COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	Q13416	ORC2	P24941	CDK2	S280	L276M	276	Missense	distal	-4	no	14.755	14.065	EPSD	TCGA;ICGC;COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	Q13416	ORC2	P24941	CDK2	S280	E286K	286	Missense	distal	6	no	14.755	14.766	EPSD	TCGA;ICGC;COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	Q96II8	LRCH3	P24941	CDK2	S255	P257S	257	Missense	proximal	2	no	12.407	12.474	EPSD	TCGA;ICGC;COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	Q96II8	LRCH3	P24941	CDK2	S255	D249Y	249	Missense	distal	-6	no	12.407	12.409	EPSD	TCGA;ICGC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	Q96II8	LRCH3	P24941	CDK2	S255	L248I	248	Missense	distal	-7	no	12.407	12.596	EPSD	TCGA;ICGC;COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	Q96II8	LRCH3	P24941	CDK2	S318	N314S	314	Missense	distal	-4	no	10.169	10.385	EPSD	TCGA;ICGC;COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	Q96II8	LRCH3	P24941	CDK2	S318	R322I	322	Missense	distal	4	no	10.169	10.261	EPSD	TCGA;ICGC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	Q96II8	LRCH3	P24941	CDK2	S324	R322I	322	Missense	proximal	-2	no	10.108	11.190	EPSD	TCGA;ICGC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	Q96II8	LRCH3	P24941	CDK2	S324	E331D	331	Missense	distal	7	no	10.108	10.750	EPSD	TCGA;ICGC;COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	Q96II8	LRCH3	P24941	CDK2	S352	Y354C	354	Missense	proximal	2	no	8.581	8.669	EPSD	TCGA;ICGC;COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	Q96II8	LRCH3	P24941	CDK2	S419	A425T	425	Missense	distal	6	no	18.277	18.289	PhosphoSitePlus	TCGA;COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	Q96II8	LRCH3	P24941	CDK2	S419	H416Y	416	Missense	distal	-3	no	18.277	18.246	PhosphoSitePlus	TCGA;COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	Q96II8	LRCH3	P24941	CDK2	S419	E417D	417	Missense	proximal	-2	no	18.277	19.257	PhosphoSitePlus	TCGA;COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	Q96II8	LRCH3	P24941	CDK2	S516	P517A	517	Missense	proximal	1	no	18.026	3.622	EPSD	TCGA;COSMIC	8.148	Loss
CMGC_CDK_CDK2_CDK2_ST	Q96II8	LRCH3	P24941	CDK2	S583	S582I	582	Missense	proximal	-1	no	13.961	14.415	EPSD	TCGA;COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	Q96II8	LRCH3	P24941	CDK2	S592	S592C	592	Missense	central	0	yes	13.948	0.000	EPSD	TCGA;COSMIC	8.148	Loss
CMGC_CDK_CDK2_CDK2_ST	Q96II8	LRCH3	P24941	CDK2	S628	P631H	631	Missense	distal	3	no	11.754	12.776	EPSD	TCGA	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	Q96II8	LRCH3	P24941	CDK2	S707	H704Y	704	Missense	distal	-3	no	13.135	13.104	EPSD	TCGA;COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	Q12800	TFCP2	P24941	CDK2	T258	R257Q	257	Missense	proximal	-1	no	16.635	15.757	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	Q12800	TFCP2	P24941	CDK2	S289	P290Q	290	Missense	proximal	1	no	12.343	4.432	PhosphoSitePlus;EPSD	TCGA;ICGC;COSMIC	8.148	Loss
CMGC_CDK_CDK2_CDK2_ST	Q12800	TFCP2	P24941	CDK2	S289	Y285F	285	Missense	distal	-4	no	12.343	11.270	PhosphoSitePlus;EPSD	TCGA;ICGC;COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	Q12800	TFCP2	P24941	CDK2	S289	E282K	282	Missense	distal	-7	no	12.343	12.206	PhosphoSitePlus;EPSD	TCGA;COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	Q12800	TFCP2	P24941	CDK2	S291	P290Q	290	Missense	proximal	-1	no	14.952	14.644	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	Q12800	TFCP2	P24941	CDK2	S291	Y285F	285	Missense	distal	-6	no	14.952	14.956	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	Q12800	TFCP2	P24941	CDK2	S309	E315Q	315	Missense	distal	6	no	18.016	18.024	EPSD;PhosphoSitePlus	TCGA;COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	Q02535	ID3	P24941	CDK2	S5	A3T	3	Missense	proximal	-2	no	12.741	12.692	PhosphoSitePlus	TCGA;ICGC;COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	Q02535	ID3	P24941	CDK2	S65	E68K	68	Missense	distal	3	no	6.928	9.014	EPSD	TCGA;ICGC;COSMIC	8.148	Gain
CMGC_CDK_CDK2_CDK2_ST	P06400	RB1	P24941	CDK2	S230	F226L	226	Missense	distal	-4	no	12.051	12.600	EPSD	TCGA;ICGC;COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	P06400	RB1	P24941	CDK2	S230	Y225C	225	Missense	distal	-5	no	12.051	12.107	EPSD	TCGA;ICGC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	P06400	RB1	P24941	CDK2	S249	R255Q	255	Missense	distal	6	no	15.721	15.743	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	P06400	RB1	P24941	CDK2	S249	R251Q	251	Missense	proximal	2	no	15.721	15.622	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC;CCLE	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	P06400	RB1	P24941	CDK2	S249	P245A	245	Missense	distal	-4	no	15.721	15.663	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	P06400	RB1	P24941	CDK2	T252	R255Q	255	Missense	distal	3	no	15.433	13.690	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	P06400	RB1	P24941	CDK2	T252	R251Q	251	Missense	proximal	-1	no	15.433	14.555	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC;CCLE	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	P06400	RB1	P24941	CDK2	T252	P245A	245	Missense	distal	-7	no	15.433	15.598	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	P06400	RB1	P24941	CDK2	T252	R259S	259	Missense	distal	7	no	15.433	14.791	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	P06400	RB1	P24941	CDK2	T356	S350I	350	Missense	distal	-6	no	17.127	17.130	PhosphoSitePlus;EPSD	TCGA;ICGC;COSMIC;GDSC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	P06400	RB1	P24941	CDK2	T373	P374A	374	Missense	proximal	1	no	17.326	2.922	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	8.148	Loss
CMGC_CDK_CDK2_CDK2_ST	P06400	RB1	P24941	CDK2	T373	M379L	379	Missense	distal	6	no	17.326	17.346	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	P06400	RB1	P24941	CDK2	S567	S567L	567	Missense	central	0	yes	12.510	0.000	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	8.148	Loss
CMGC_CDK_CDK2_CDK2_ST	P06400	RB1	P24941	CDK2	S567	W563S	563	Missense	distal	-4	no	12.510	13.865	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	P06400	RB1	P24941	CDK2	S567	A562E	562	Missense	distal	-5	no	12.510	12.522	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	P06400	RB1	P24941	CDK2	S608	D604G	604	Missense	distal	-4	no	15.720	14.875	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	P06400	RB1	P24941	CDK2	S780	I782M	782	Missense	proximal	2	no	13.523	13.757	EPSD	TCGA;ICGC;COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	P06400	RB1	P24941	CDK2	S780	R787Q	787	Missense	distal	7	no	13.523	12.879	EPSD	TCGA;ICGC;COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	P06400	RB1	P24941	CDK2	S788	I782M	782	Missense	distal	-6	no	15.922	15.927	EPSD	TCGA;ICGC;COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	P06400	RB1	P24941	CDK2	S788	S788N	788	Missense	central	0	yes	15.922	0.000	EPSD	TCGA;ICGC;COSMIC	8.148	Loss
CMGC_CDK_CDK2_CDK2_ST	P06400	RB1	P24941	CDK2	S788	R787Q	787	Missense	proximal	-1	no	15.922	15.044	EPSD	TCGA;ICGC;COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	P06400	RB1	P24941	CDK2	S795	S788N	788	Missense	distal	-7	no	14.101	14.199	EPSD	TCGA;ICGC;COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	P06400	RB1	P24941	CDK2	S795	R798W	798	Missense	distal	3	no	14.101	11.461	EPSD	TCGA;ICGC;COSMIC;GDSC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	P06400	RB1	P24941	CDK2	S807	N803S	803	Missense	distal	-4	no	16.149	16.365	EPSD;PhosphoSitePlus	TCGA;ICGC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	P06400	RB1	P24941	CDK2	T821	P827S	827	Missense	distal	6	no	14.278	14.279	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	P06400	RB1	P24941	CDK2	T826	P827S	827	Missense	proximal	1	no	15.388	4.122	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	8.148	Loss
CMGC_CDK_CDK2_CDK2_ST	O00267	SUPT5H	P24941	CDK2	S36	R31Q	31	Missense	distal	-5	no	8.329	8.282	EPSD	TCGA;ICGC;COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	O00267	SUPT5H	P24941	CDK2	S36	R30W	30	Missense	distal	-6	no	8.329	8.335	EPSD	TCGA;ICGC;COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	O00267	SUPT5H	P24941	CDK2	S120	R123H	123	Missense	distal	3	no	9.341	8.645	EPSD	TCGA;COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	O00267	SUPT5H	P24941	CDK2	S120	R119C	119	Missense	proximal	-1	no	9.341	8.644	EPSD	TCGA;ICGC;COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	O00267	SUPT5H	P24941	CDK2	S120	R124H	124	Missense	distal	4	no	9.341	9.224	EPSD	TCGA;ICGC;COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	O00267	SUPT5H	P24941	CDK2	T208	T206R	206	Missense	proximal	-2	no	16.583	15.380	EPSD	TCGA;ICGC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	O00267	SUPT5H	P24941	CDK2	T208	A202T	202	Missense	distal	-6	no	16.583	16.584	EPSD	TCGA;ICGC;COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	O00267	SUPT5H	P24941	CDK2	S379	A380T	380	Missense	proximal	1	no	4.516	8.962	EPSD	TCGA;ICGC;COSMIC	8.148	Gain
CMGC_CDK_CDK2_CDK2_ST	O00267	SUPT5H	P24941	CDK2	S391	E392G	392	Missense	proximal	1	no	6.446	8.299	EPSD	TCGA;ICGC;COSMIC	8.148	Gain
CMGC_CDK_CDK2_CDK2_ST	O00267	SUPT5H	P24941	CDK2	S666	I669T	669	Missense	distal	3	no	13.176	13.729	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	O00267	SUPT5H	P24941	CDK2	S666	A663T	663	Missense	distal	-3	no	13.176	13.194	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	O00267	SUPT5H	P24941	CDK2	S671	A677D	677	Missense	distal	6	no	15.389	15.378	EPSD	TCGA;ICGC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	O00267	SUPT5H	P24941	CDK2	S671	I669T	669	Missense	proximal	-2	no	15.389	15.510	EPSD	TCGA;ICGC;COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	O00267	SUPT5H	P24941	CDK2	S686	F684C	684	Missense	proximal	-2	no	14.410	14.461	EPSD	TCGA;ICGC;COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	O00267	SUPT5H	P24941	CDK2	S691	R696W	696	Missense	distal	5	no	8.160	8.327	EPSD	TCGA;ICGC;COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	O00267	SUPT5H	P24941	CDK2	S691	R696M	696	Missense	distal	5	no	8.160	8.362	EPSD	TCGA;ICGC;COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	O00267	SUPT5H	P24941	CDK2	S691	F684C	684	Missense	distal	-7	no	8.160	8.060	EPSD	TCGA;ICGC;COSMIC	8.148	Loss
CMGC_CDK_CDK2_CDK2_ST	O00267	SUPT5H	P24941	CDK2	S695	R700Q	700	Missense	distal	5	no	8.189	8.043	EPSD	TCGA;ICGC;COSMIC	8.148	Loss
CMGC_CDK_CDK2_CDK2_ST	O00267	SUPT5H	P24941	CDK2	S695	R696W	696	Missense	proximal	1	no	8.189	2.765	EPSD	TCGA;ICGC;COSMIC	8.148	Loss
CMGC_CDK_CDK2_CDK2_ST	O00267	SUPT5H	P24941	CDK2	S695	R696M	696	Missense	proximal	1	no	8.189	-8.825	EPSD	TCGA;ICGC;COSMIC	8.148	Loss
CMGC_CDK_CDK2_CDK2_ST	O00267	SUPT5H	P24941	CDK2	S695	R700L	700	Missense	distal	5	no	8.189	8.123	EPSD	TCGA;ICGC;COSMIC	8.148	Loss
CMGC_CDK_CDK2_CDK2_ST	O00267	SUPT5H	P24941	CDK2	T768	Y765C	765	Missense	distal	-3	no	13.954	13.942	EPSD	TCGA;ICGC;COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	O00267	SUPT5H	P24941	CDK2	T768	T775M	775	Missense	distal	7	no	13.954	14.803	EPSD	TCGA;ICGC;COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	O00267	SUPT5H	P24941	CDK2	T768	T762I	762	Missense	distal	-6	no	13.954	13.956	EPSD	TCGA;ICGC;COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	O00267	SUPT5H	P24941	CDK2	T775	T775M	775	Missense	central	0	yes	13.036	0.000	PhosphoSitePlus;EPSD	TCGA;ICGC;COSMIC	8.148	Loss
CMGC_CDK_CDK2_CDK2_ST	O00267	SUPT5H	P24941	CDK2	S780	T775M	775	Missense	distal	-5	no	11.206	11.314	EPSD	TCGA;ICGC;COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	O00267	SUPT5H	P24941	CDK2	T791	D795Y	795	Missense	distal	4	no	12.170	12.435	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	O00267	SUPT5H	P24941	CDK2	T791	G796D	796	Missense	distal	5	no	12.170	12.217	EPSD;PhosphoSitePlus	TCGA;ICGC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	O00267	SUPT5H	P24941	CDK2	T799	D795Y	795	Missense	distal	-4	no	10.863	10.802	EPSD	TCGA;ICGC;COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	O00267	SUPT5H	P24941	CDK2	T799	G796D	796	Missense	distal	-3	no	10.863	10.825	EPSD	TCGA;ICGC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	O00267	SUPT5H	P24941	CDK2	T806	R813H	813	Missense	distal	7	no	17.093	16.734	EPSD	TCGA;ICGC;COSMIC;CCLE	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	O00267	SUPT5H	P24941	CDK2	T806	S812C	812	Missense	distal	6	no	17.093	17.078	EPSD	TCGA;ICGC;COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	O00267	SUPT5H	P24941	CDK2	T806	S812N	812	Missense	distal	6	no	17.093	17.095	EPSD	TCGA;ICGC;COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	O00267	SUPT5H	P24941	CDK2	T814	R813H	813	Missense	proximal	-1	no	13.463	13.011	EPSD	TCGA;ICGC;COSMIC;CCLE	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	O00267	SUPT5H	P24941	CDK2	T814	Q817H	817	Missense	distal	3	no	13.463	14.510	EPSD	TCGA;ICGC;COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	O00267	SUPT5H	P24941	CDK2	T814	Q817K	817	Missense	distal	3	no	13.463	16.195	EPSD	TCGA;ICGC;COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	O00267	SUPT5H	P24941	CDK2	T814	S812C	812	Missense	proximal	-2	no	13.463	13.052	EPSD	TCGA;ICGC;COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	O00267	SUPT5H	P24941	CDK2	T814	S812N	812	Missense	proximal	-2	no	13.463	12.771	EPSD	TCGA;ICGC;COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	O00267	SUPT5H	P24941	CDK2	S867	N871K	871	Missense	distal	4	no	15.527	15.948	EPSD	TCGA;ICGC;COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	O00267	SUPT5H	P24941	CDK2	T878	P882L	882	Missense	distal	4	no	11.338	11.450	EPSD	TCGA;ICGC;COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	O00267	SUPT5H	P24941	CDK2	T878	Y885H	885	Missense	distal	7	no	11.338	11.200	EPSD	TCGA;ICGC;COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	O00267	SUPT5H	P24941	CDK2	T878	N871K	871	Missense	distal	-7	no	11.338	11.373	EPSD	TCGA;ICGC;COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	O00267	SUPT5H	P24941	CDK2	T878	P882Q	882	Missense	distal	4	no	11.338	11.399	EPSD	TCGA;ICGC;COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	O00267	SUPT5H	P24941	CDK2	T881	P882L	882	Missense	proximal	1	no	14.252	4.431	EPSD	TCGA;ICGC;COSMIC	8.148	Loss
CMGC_CDK_CDK2_CDK2_ST	O00267	SUPT5H	P24941	CDK2	T881	Y885H	885	Missense	distal	4	no	14.252	13.815	EPSD	TCGA;ICGC;COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	O00267	SUPT5H	P24941	CDK2	T881	P882Q	882	Missense	proximal	1	no	14.252	6.340	EPSD	TCGA;ICGC;COSMIC	8.148	Loss
CMGC_CDK_CDK2_CDK2_ST	O00267	SUPT5H	P24941	CDK2	S897	S891F	891	Missense	distal	-6	no	12.335	12.340	EPSD	TCGA;ICGC;COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	O00267	SUPT5H	P24941	CDK2	S897	F890L	890	Missense	distal	-7	no	12.335	11.969	EPSD	TCGA;ICGC;COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	O00267	SUPT5H	P24941	CDK2	S917	Q922H	922	Missense	distal	5	no	13.723	13.842	EPSD	TCGA;ICGC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	O00267	SUPT5H	P24941	CDK2	S917	Y911H	911	Missense	distal	-6	no	13.723	13.727	EPSD	TCGA;ICGC;COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	O00267	SUPT5H	P24941	CDK2	S917	G920D	920	Missense	distal	3	no	13.723	12.011	EPSD	TCGA;ICGC;COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	O00267	SUPT5H	P24941	CDK2	S917	A915V	915	Missense	proximal	-2	no	13.723	13.058	EPSD	TCGA;ICGC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	O00267	SUPT5H	P24941	CDK2	T967	G969C	969	Missense	proximal	2	no	13.793	13.821	EPSD	TCGA;ICGC;COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	O00267	SUPT5H	P24941	CDK2	T967	S970L	970	Missense	distal	3	no	13.793	13.375	EPSD	TCGA;ICGC;COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	O00267	SUPT5H	P24941	CDK2	S970	G969C	969	Missense	proximal	-1	no	8.711	7.535	EPSD	TCGA;ICGC;COSMIC	8.148	Loss
CMGC_CDK_CDK2_CDK2_ST	O00267	SUPT5H	P24941	CDK2	S970	S970L	970	Missense	central	0	yes	8.711	0.000	EPSD	TCGA;ICGC;COSMIC	8.148	Loss
CMGC_CDK_CDK2_CDK2_ST	O00267	SUPT5H	P24941	CDK2	T1034	E1028D	1028	Missense	distal	-6	no	15.546	15.542	EPSD	TCGA;ICGC;COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	Q9UQR0	SCML2	P24941	CDK2	T20	S26F	26	Missense	distal	6	no	13.411	13.392	EPSD	TCGA;ICGC;COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	Q9UQR0	SCML2	P24941	CDK2	T20	S26Y	26	Missense	distal	6	no	13.411	13.402	EPSD	TCGA;ICGC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	Q9UQR0	SCML2	P24941	CDK2	S256	S255F	255	Missense	proximal	-1	no	13.781	15.038	EPSD	TCGA;ICGC;COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	Q9UQR0	SCML2	P24941	CDK2	S256	A260E	260	Missense	distal	4	no	13.781	13.758	EPSD	TCGA;ICGC;COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	Q9UQR0	SCML2	P24941	CDK2	S256	P257S	257	Missense	proximal	1	no	13.781	2.516	EPSD	TCGA;ICGC;COSMIC	8.148	Loss
CMGC_CDK_CDK2_CDK2_ST	Q9UQR0	SCML2	P24941	CDK2	S256	P257L	257	Missense	proximal	1	no	13.781	3.961	EPSD	TCGA;ICGC;COSMIC	8.148	Loss
CMGC_CDK_CDK2_CDK2_ST	Q9UQR0	SCML2	P24941	CDK2	S256	Q262H	262	Missense	distal	6	no	13.781	13.771	EPSD	TCGA;ICGC;COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	Q9UQR0	SCML2	P24941	CDK2	S267	A260E	260	Missense	distal	-7	no	13.843	13.768	EPSD	TCGA;ICGC;COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	Q9UQR0	SCML2	P24941	CDK2	S267	Q262H	262	Missense	distal	-5	no	13.843	13.889	EPSD	TCGA;ICGC;COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	Q9UQR0	SCML2	P24941	CDK2	T305	R307S	307	Missense	proximal	2	no	16.735	16.643	PhosphoSitePlus;EPSD	TCGA;ICGC;COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	Q9UQR0	SCML2	P24941	CDK2	T305	P306Q	306	Missense	proximal	1	no	16.735	8.824	PhosphoSitePlus;EPSD	TCGA;ICGC;COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	Q9UQR0	SCML2	P24941	CDK2	T305	P311S	311	Missense	distal	6	no	16.735	16.737	PhosphoSitePlus;EPSD	TCGA;ICGC;COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	Q9UQR0	SCML2	P24941	CDK2	T305	K302T	302	Missense	distal	-3	no	16.735	16.736	PhosphoSitePlus;EPSD	TCGA;ICGC;COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	Q9UQR0	SCML2	P24941	CDK2	S499	T503P	503	Missense	distal	4	no	14.383	14.101	EPSD	TCGA;ICGC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	Q9UQR0	SCML2	P24941	CDK2	S499	R498L	498	Missense	proximal	-1	no	14.383	13.633	EPSD	TCGA;ICGC;COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	Q9UQR0	SCML2	P24941	CDK2	S583	V586F	586	Missense	distal	3	no	14.962	14.312	EPSD	TCGA;ICGC;COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	Q9UQR0	SCML2	P24941	CDK2	S583	V577A	577	Missense	distal	-6	no	14.962	14.959	EPSD	TCGA;ICGC;COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	Q9UQR0	SCML2	P24941	CDK2	S583	G579D	579	Missense	distal	-4	no	14.962	15.806	EPSD	TCGA;ICGC;COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	Q9UQR0	SCML2	P24941	CDK2	S590	H596L	596	Missense	distal	6	no	11.413	11.419	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	Q9UQR0	SCML2	P24941	CDK2	S590	V586F	586	Missense	distal	-4	no	11.413	10.853	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	Q9UQR0	SCML2	P24941	CDK2	S594	H596L	596	Missense	proximal	2	no	14.045	13.860	EPSD	TCGA;ICGC;COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	P10275	AR	P24941	CDK2	S96	G95S	95	Missense	proximal	-1	no	13.938	12.419	PhosphoSitePlus	TCGA;ICGC;COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	P10275	AR	P24941	CDK2	S96	E93D	93	Missense	distal	-3	no	13.938	13.828	PhosphoSitePlus	TCGA;ICGC;COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	P10275	AR	P24941	CDK2	S258	R264W	264	Missense	distal	6	no	13.449	13.442	EPSD	TCGA;ICGC;COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	P10275	AR	P24941	CDK2	S258	A253V	253	Missense	distal	-5	no	13.449	13.455	EPSD	TCGA;ICGC;COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	P10275	AR	P24941	CDK2	T282	E289K	289	Missense	distal	7	no	10.776	10.445	EPSD	TCGA;ICGC;COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	P10275	AR	P24941	CDK2	T282	R280C	280	Missense	proximal	-2	no	10.776	10.950	EPSD	TCGA;ICGC;COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	P10275	AR	P24941	CDK2	S298	A299T	299	Missense	proximal	1	no	4.776	9.223	EPSD	TCGA;ICGC;COSMIC	8.148	Gain
CMGC_CDK_CDK2_CDK2_ST	P10275	AR	P24941	CDK2	S310	E308K	308	Missense	proximal	-2	no	17.226	17.827	EPSD	TCGA;COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	P10275	AR	P24941	CDK2	S310	Y316H	316	Missense	distal	6	no	17.226	17.229	EPSD	TCGA;ICGC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	P10275	AR	P24941	CDK2	S516	P513S	513	Missense	distal	-3	no	9.037	9.133	EPSD	TCGA;ICGC;COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	P10275	AR	P24941	CDK2	S651	E645K	645	Missense	distal	-6	no	16.006	16.003	EPSD	TCGA;ICGC;COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	P10275	AR	P24941	CDK2	S792	M788I	788	Missense	distal	-4	no	8.373	8.970	EPSD	TCGA;ICGC;COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	P10275	AR	P24941	CDK2	S792	R787Q	787	Missense	distal	-5	no	8.373	8.326	EPSD	TCGA;ICGC;COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	P10275	AR	P24941	CDK2	S792	L791I	791	Missense	proximal	-1	no	8.373	8.535	EPSD	TCGA;ICGC;COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	P10275	AR	P24941	CDK2	S792	G796V	796	Missense	distal	4	no	8.373	8.720	EPSD	TCGA;ICGC;COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	O43395	PRPF3	P24941	CDK2	S106	E100K	100	Missense	distal	-6	no	8.829	8.827	EPSD	TCGA;ICGC;COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	O43395	PRPF3	P24941	CDK2	S133	T138I	138	Missense	distal	5	no	14.346	14.465	EPSD	TCGA;ICGC;COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	O43395	PRPF3	P24941	CDK2	S133	P127S	127	Missense	distal	-6	no	14.346	14.345	EPSD	TCGA;ICGC;COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	O43395	PRPF3	P24941	CDK2	S133	M136I	136	Missense	distal	3	no	14.346	13.918	EPSD	TCGA;ICGC;COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	O43395	PRPF3	P24941	CDK2	S164	K171N	171	Missense	distal	7	no	13.379	13.572	EPSD	TCGA;COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	O43395	PRPF3	P24941	CDK2	S164	L160M	160	Missense	distal	-4	no	13.379	12.689	EPSD	TCGA;COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	O43395	PRPF3	P24941	CDK2	T167	K171N	171	Missense	distal	4	no	14.827	14.405	PhosphoSitePlus	TCGA;COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	O43395	PRPF3	P24941	CDK2	T167	P173S	173	Missense	distal	6	no	14.827	14.828	PhosphoSitePlus	TCGA;COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	O43395	PRPF3	P24941	CDK2	T167	P173L	173	Missense	distal	6	no	14.827	14.828	PhosphoSitePlus	TCGA;COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	O43395	PRPF3	P24941	CDK2	T167	L160M	160	Missense	distal	-7	no	14.827	15.322	PhosphoSitePlus	TCGA;COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	O43395	PRPF3	P24941	CDK2	T172	E179K	179	Missense	distal	7	no	13.442	13.111	EPSD	TCGA;COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	O43395	PRPF3	P24941	CDK2	T172	K171N	171	Missense	proximal	-1	no	13.442	13.468	EPSD	TCGA;COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	O43395	PRPF3	P24941	CDK2	T172	P173S	173	Missense	proximal	1	no	13.442	2.176	EPSD	TCGA;COSMIC	8.148	Loss
CMGC_CDK_CDK2_CDK2_ST	O43395	PRPF3	P24941	CDK2	T172	P173L	173	Missense	proximal	1	no	13.442	3.621	EPSD	TCGA;COSMIC	8.148	Loss
CMGC_CDK_CDK2_CDK2_ST	O43395	PRPF3	P24941	CDK2	T254	P255S	255	Missense	proximal	1	no	11.765	0.500	EPSD	TCGA;COSMIC	8.148	Loss
CMGC_CDK_CDK2_CDK2_ST	O43395	PRPF3	P24941	CDK2	T254	T251M	251	Missense	distal	-3	no	11.765	12.173	EPSD	TCGA;COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	O43395	PRPF3	P24941	CDK2	T254	T254I	254	Missense	central	0	yes	11.765	0.000	EPSD	TCGA	8.148	Loss
CMGC_CDK_CDK2_CDK2_ST	O43395	PRPF3	P24941	CDK2	S320	S316F	316	Missense	distal	-4	no	10.036	9.074	EPSD	TCGA;COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	O43395	PRPF3	P24941	CDK2	S320	R324I	324	Missense	distal	4	no	10.036	10.127	EPSD	TCGA	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	O43395	PRPF3	P24941	CDK2	T432	N430S	430	Missense	proximal	-2	no	14.759	15.451	EPSD	TCGA;COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	O43395	PRPF3	P24941	CDK2	T432	Y439C	439	Missense	distal	7	no	14.759	15.131	EPSD	TCGA;COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	O43395	PRPF3	P24941	CDK2	S619	K626N	626	Missense	distal	7	no	9.117	9.310	EPSD	TCGA;COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	O43395	PRPF3	P24941	CDK2	S619	D616N	616	Missense	distal	-3	no	9.117	9.073	EPSD	TCGA;COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	O43395	PRPF3	P24941	CDK2	S619	E618D	618	Missense	proximal	-1	no	9.117	9.088	EPSD	TCGA;COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	P50750	CDK9	P24941	CDK2	S90	R86Q	86	Missense	distal	-4	no	14.155	14.180	PhosphoSitePlus	TCGA;ICGC;COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	P50750	CDK9	P24941	CDK2	S90	N93T	93	Missense	distal	3	no	14.155	14.604	PhosphoSitePlus	TCGA;ICGC;COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	P50750	CDK9	P24941	CDK2	S175	F168S	168	Missense	distal	-7	no	8.210	7.659	EPSD	TCGA;ICGC;COSMIC	8.148	Loss
CMGC_CDK_CDK2_CDK2_ST	P50750	CDK9	P24941	CDK2	S347	Q352H	352	Missense	distal	5	no	8.180	8.298	EPSD	TCGA;ICGC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	Q9Y676	MRPS18B	P24941	CDK2	S49	P50H	50	Missense	proximal	1	no	18.412	11.653	PhosphoSitePlus	TCGA;ICGC;COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	Q9Y676	MRPS18B	P24941	CDK2	S49	S44F	44	Missense	distal	-5	no	18.412	18.528	PhosphoSitePlus	TCGA;ICGC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	Q9Y676	MRPS18B	P24941	CDK2	S70	R71H	71	Missense	proximal	1	no	6.353	9.393	EPSD	TCGA;ICGC;COSMIC	8.148	Gain
CMGC_CDK_CDK2_CDK2_ST	P46527	CDKN1B	P24941	CDK2	S10	S7C	7	Missense	distal	-3	no	12.148	12.156	EPSD	TCGA;ICGC;COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	P46527	CDKN1B	P24941	CDK2	S10	G9W	9	Missense	proximal	-1	no	12.148	12.224	EPSD	TCGA;ICGC;COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	P46527	CDKN1B	P24941	CDK2	S110	A116S	116	Missense	distal	6	no	9.560	9.566	EPSD	TCGA;ICGC;COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	P46527	CDKN1B	P24941	CDK2	S110	A103V	103	Missense	distal	-7	no	9.560	9.415	EPSD	TCGA;ICGC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	Q13415	ORC1	P24941	CDK2	S199	K193N	193	Missense	distal	-6	no	13.086	13.085	EPSD	TCGA;ICGC;COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	Q13415	ORC1	P24941	CDK2	S199	S201F	201	Missense	proximal	2	no	13.086	13.270	EPSD	TCGA;ICGC;COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	Q13415	ORC1	P24941	CDK2	T203	S201F	201	Missense	proximal	-2	no	13.636	13.174	EPSD	TCGA;ICGC;COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	Q13415	ORC1	P24941	CDK2	T203	V208M	208	Missense	distal	5	no	13.636	13.977	EPSD	TCGA;ICGC;COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	Q13415	ORC1	P24941	CDK2	T224	R222H	222	Missense	proximal	-2	no	11.701	11.927	EPSD	TCGA;ICGC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	Q13415	ORC1	P24941	CDK2	S258	R264W	264	Missense	distal	6	no	15.023	15.016	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	Q13415	ORC1	P24941	CDK2	S273	R277I	277	Missense	distal	4	no	16.209	16.301	PhosphoSitePlus;EPSD	TCGA;ICGC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	Q13415	ORC1	P24941	CDK2	S287	D281H	281	Missense	distal	-6	no	14.037	14.042	EPSD	TCGA;ICGC;COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	Q13415	ORC1	P24941	CDK2	S287	S287Y	287	Missense	central	0	yes	14.037	0.000	EPSD	TCGA;ICGC	8.148	Loss
CMGC_CDK_CDK2_CDK2_ST	Q13415	ORC1	P24941	CDK2	S287	L283I	283	Missense	distal	-4	no	14.037	13.944	EPSD	TCGA;ICGC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	Q13415	ORC1	P24941	CDK2	S311	A310D	310	Missense	proximal	-1	no	14.749	15.775	EPSD	TCGA;ICGC;COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	Q13415	ORC1	P24941	CDK2	S311	R315C	315	Missense	distal	4	no	14.749	14.122	EPSD	TCGA;ICGC;COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	Q13415	ORC1	P24941	CDK2	T337	R334I	334	Missense	distal	-3	no	14.126	13.958	EPSD	TCGA;ICGC;COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	Q13415	ORC1	P24941	CDK2	T375	R378C	378	Missense	distal	3	no	15.014	8.650	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	Q13415	ORC1	P24941	CDK2	T375	R378H	378	Missense	distal	3	no	15.014	14.317	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	Q13415	ORC1	P24941	CDK2	T428	S421I	421	Missense	distal	-7	no	14.917	15.291	EPSD	TCGA;ICGC;COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	Q13415	ORC1	P24941	CDK2	S610	G609E	609	Missense	proximal	-1	no	16.736	16.472	EPSD	TCGA;ICGC;COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	P54132	BLM	P24941	CDK2	T57	R61K	61	Missense	distal	4	no	14.943	15.464	EPSD	TCGA;ICGC;COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	P54132	BLM	P24941	CDK2	T114	D110N	110	Missense	distal	-4	no	13.353	12.965	EPSD	TCGA;ICGC;COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	P54132	BLM	P24941	CDK2	T125	T125P	125	Missense	central	0	yes	14.320	0.000	EPSD	TCGA;ICGC;COSMIC	8.148	Loss
CMGC_CDK_CDK2_CDK2_ST	P54132	BLM	P24941	CDK2	T125	R132W	132	Missense	distal	7	no	14.320	14.719	EPSD	TCGA;ICGC;COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	P54132	BLM	P24941	CDK2	T171	S175I	175	Missense	distal	4	no	11.025	10.983	EPSD	TCGA;ICGC;COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	P54132	BLM	P24941	CDK2	S282	E279K	279	Missense	distal	-3	no	9.693	9.478	EPSD	TCGA;ICGC;COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	P54132	BLM	P24941	CDK2	S304	S310C	310	Missense	distal	6	no	12.972	12.957	EPSD	TCGA;ICGC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	P54132	BLM	P24941	CDK2	S304	F300C	300	Missense	distal	-4	no	12.972	12.828	EPSD	TCGA;ICGC;COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	P54132	BLM	P24941	CDK2	S328	S328C	328	Missense	central	0	yes	9.400	0.000	EPSD	TCGA;ICGC;COSMIC	8.148	Loss
CMGC_CDK_CDK2_CDK2_ST	P54132	BLM	P24941	CDK2	S328	L335F	335	Missense	distal	7	no	9.400	10.071	EPSD	TCGA;ICGC;COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	P54132	BLM	P24941	CDK2	S426	D433H	433	Missense	distal	7	no	9.048	8.493	EPSD	TCGA;ICGC;COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	P54132	BLM	P24941	CDK2	S426	R431K	431	Missense	distal	5	no	9.048	8.888	EPSD	TCGA;ICGC;COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	P54132	BLM	P24941	CDK2	S426	R429K	429	Missense	distal	3	no	9.048	10.037	EPSD	TCGA;ICGC;COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	P54132	BLM	P24941	CDK2	S426	D420G	420	Missense	distal	-6	no	9.048	9.052	EPSD	TCGA;ICGC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	P54132	BLM	P24941	CDK2	S464	S462Y	462	Missense	proximal	-2	no	10.585	10.672	EPSD	TCGA;ICGC;COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	P54132	BLM	P24941	CDK2	T473	F479L	479	Missense	distal	6	no	8.194	8.213	EPSD	TCGA;ICGC;COSMIC;GDSC;CCLE	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	P54132	BLM	P24941	CDK2	T508	L511I	511	Missense	distal	3	no	11.924	11.640	EPSD	TCGA;ICGC;COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	P54132	BLM	P24941	CDK2	S706	C704R	704	Missense	proximal	-2	no	14.649	14.475	EPSD	TCGA	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	P54132	BLM	P24941	CDK2	S714	P715L	715	Missense	proximal	1	no	14.707	4.886	EPSD	TCGA;ICGC;COSMIC	8.148	Loss
CMGC_CDK_CDK2_CDK2_ST	P54132	BLM	P24941	CDK2	T766	L763I	763	Missense	distal	-3	no	16.368	16.459	EPSD	TCGA;ICGC;COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	P54132	BLM	P24941	CDK2	T907	R910T	910	Missense	distal	3	no	9.347	7.514	EPSD	TCGA;ICGC;COSMIC	8.148	Loss
CMGC_CDK_CDK2_CDK2_ST	P54132	BLM	P24941	CDK2	T907	D902H	902	Missense	distal	-5	no	9.347	9.336	EPSD	TCGA;ICGC;COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	P54132	BLM	P24941	CDK2	T907	A914T	914	Missense	distal	7	no	9.347	8.658	EPSD	TCGA;ICGC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	P54132	BLM	P24941	CDK2	T907	L913R	913	Missense	distal	6	no	9.347	9.329	EPSD	TCGA;ICGC;COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	O00429	DNM1L	P24941	CDK2	T400	I396S	396	Missense	distal	-4	no	8.145	8.650	EPSD	TCGA;COSMIC	8.148	Gain
CMGC_CDK_CDK2_CDK2_ST	O00429	DNM1L	P24941	CDK2	S616	A622V	622	Missense	distal	6	no	16.062	16.065	PhosphoSitePlus	TCGA;COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	O00429	DNM1L	P24941	CDK2	S616	G620C	620	Missense	distal	4	no	16.062	15.435	PhosphoSitePlus	TCGA	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	Q8IXM2	C17orf49	P24941	CDK2	S36	L29V	29	Missense	distal	-7	no	12.637	12.651	EPSD	TCGA;ICGC;COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	Q8IXM2	C17orf49	P24941	CDK2	S36	A40V	40	Missense	distal	4	no	12.637	12.824	EPSD	TCGA;ICGC;COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	Q8IXM2	C17orf49	P24941	CDK2	S96	L92F	92	Missense	distal	-4	no	15.428	14.879	PhosphoSitePlus	TCGA;ICGC;COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	Q8IXM2	C17orf49	P24941	CDK2	T161	E156Q	156	Missense	distal	-5	no	13.777	13.740	EPSD	TCGA;ICGC;COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	Q8IXM2	C17orf49	P24941	CDK2	T161	K165T	165	Missense	distal	4	no	13.777	13.658	EPSD	TCGA;ICGC;COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	Q8IXM2	C17orf49	P24941	CDK2	T161	I155T	155	Missense	distal	-6	no	13.777	13.774	EPSD	TCGA;ICGC;COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	Q8IXM2	C17orf49	P24941	CDK2	T161	E160K	160	Missense	proximal	-1	no	13.777	12.892	EPSD	TCGA;ICGC;COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	P28749	RBL1	P24941	CDK2	T332	A326T	326	Missense	distal	-6	no	18.255	18.256	EPSD	TCGA;ICGC;COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	P28749	RBL1	P24941	CDK2	T332	R338C	338	Missense	distal	6	no	18.255	18.258	EPSD	TCGA;ICGC;COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	P28749	RBL1	P24941	CDK2	T332	R334Q	334	Missense	proximal	2	no	18.255	18.155	EPSD	TCGA;ICGC;COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	P28749	RBL1	P24941	CDK2	T332	R338H	338	Missense	distal	6	no	18.255	18.266	EPSD	TCGA;ICGC;COSMIC;GDSC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	P28749	RBL1	P24941	CDK2	T340	R338C	338	Missense	proximal	-2	no	13.989	14.163	EPSD	TCGA;ICGC;COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	P28749	RBL1	P24941	CDK2	T340	R334Q	334	Missense	distal	-6	no	13.989	13.990	EPSD	TCGA;ICGC;COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	P28749	RBL1	P24941	CDK2	T340	R338H	338	Missense	proximal	-2	no	13.989	14.215	EPSD	TCGA;ICGC;COSMIC;GDSC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	P28749	RBL1	P24941	CDK2	T369	Y376H	376	Missense	distal	7	no	12.875	12.737	EPSD	TCGA	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	P28749	RBL1	P24941	CDK2	T385	S389L	389	Missense	distal	4	no	12.535	12.633	EPSD	TCGA;ICGC;COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	P28749	RBL1	P24941	CDK2	T385	Q392K	392	Missense	distal	7	no	12.535	12.403	EPSD	TCGA;ICGC;COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	P28749	RBL1	P24941	CDK2	T385	A382S	382	Missense	distal	-3	no	12.535	12.688	EPSD	TCGA;ICGC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	P28749	RBL1	P24941	CDK2	S615	L617V	617	Missense	proximal	2	no	17.319	17.549	EPSD	TCGA;ICGC;COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	P28749	RBL1	P24941	CDK2	S615	M618I	618	Missense	distal	3	no	17.319	16.891	EPSD	TCGA;ICGC;COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	P28749	RBL1	P24941	CDK2	S640	R633Q	633	Missense	distal	-7	no	14.260	13.874	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	P28749	RBL1	P24941	CDK2	S640	R647C	647	Missense	distal	7	no	14.260	14.411	EPSD;PhosphoSitePlus	TCGA;ICGC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	P28749	RBL1	P24941	CDK2	S650	S650A	650	Missense	central	0	yes	13.655	0.000	PhosphoSitePlus;EPSD	TCGA;ICGC;COSMIC	8.148	Loss
CMGC_CDK_CDK2_CDK2_ST	P28749	RBL1	P24941	CDK2	S650	A653T	653	Missense	distal	3	no	13.655	14.053	PhosphoSitePlus;EPSD	TCGA;ICGC;COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	P28749	RBL1	P24941	CDK2	S650	S650F	650	Missense	central	0	yes	13.655	0.000	PhosphoSitePlus;EPSD	TCGA;ICGC	8.148	Loss
CMGC_CDK_CDK2_CDK2_ST	P28749	RBL1	P24941	CDK2	S650	R647C	647	Missense	distal	-3	no	13.655	13.570	PhosphoSitePlus;EPSD	TCGA;ICGC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	P28749	RBL1	P24941	CDK2	S749	K748N	748	Missense	proximal	-1	no	13.135	13.161	EPSD	TCGA;ICGC;COSMIC;CCLE	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	P28749	RBL1	P24941	CDK2	S749	H756N	756	Missense	distal	7	no	13.135	12.910	EPSD	TCGA;ICGC;COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	P28749	RBL1	P24941	CDK2	S762	S757L	757	Missense	distal	-5	no	13.711	13.767	EPSD	TCGA;ICGC;COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	P28749	RBL1	P24941	CDK2	S762	H756N	756	Missense	distal	-6	no	13.711	13.706	EPSD	TCGA;ICGC;COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	P28749	RBL1	P24941	CDK2	T915	C918S	918	Missense	distal	3	no	7.835	12.515	EPSD	TCGA;ICGC;COSMIC	8.148	Gain
CMGC_CDK_CDK2_CDK2_ST	P28749	RBL1	P24941	CDK2	S964	P965L	965	Missense	proximal	1	no	14.832	5.011	EPSD	TCGA;ICGC;COSMIC	8.148	Loss
CMGC_CDK_CDK2_CDK2_ST	P28749	RBL1	P24941	CDK2	S964	P965S	965	Missense	proximal	1	no	14.832	3.566	EPSD	TCGA;ICGC;COSMIC	8.148	Loss
CMGC_CDK_CDK2_CDK2_ST	P28749	RBL1	P24941	CDK2	S964	A960D	960	Missense	distal	-4	no	14.832	15.418	EPSD	TCGA;ICGC;COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	P28749	RBL1	P24941	CDK2	S975	R978H	978	Missense	distal	3	no	15.212	14.516	EPSD	TCGA;COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	P28749	RBL1	P24941	CDK2	S988	P989L	989	Missense	proximal	1	no	16.752	6.931	EPSD	TCGA;ICGC;COSMIC	8.148	Loss
CMGC_CDK_CDK2_CDK2_ST	P28749	RBL1	P24941	CDK2	T997	A1001T	1001	Missense	distal	4	no	15.469	15.712	EPSD	TCGA;ICGC;COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	P28749	RBL1	P24941	CDK2	T997	L996R	996	Missense	proximal	-1	no	15.469	16.219	EPSD	TCGA;ICGC;COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	P28749	RBL1	P24941	CDK2	S1009	G1008V	1008	Missense	proximal	-1	no	17.199	16.107	EPSD	TCGA;ICGC;COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	P28749	RBL1	P24941	CDK2	S1009	G1008C	1008	Missense	proximal	-1	no	17.199	16.023	EPSD	TCGA;ICGC;COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	P28749	RBL1	P24941	CDK2	S1041	V1046F	1046	Missense	distal	5	no	16.162	16.412	EPSD	TCGA;ICGC;COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	P28749	RBL1	P24941	CDK2	S1041	A1034S	1034	Missense	distal	-7	no	16.162	15.817	EPSD	TCGA;ICGC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	P28749	RBL1	P24941	CDK2	S1041	V1046I	1046	Missense	distal	5	no	16.162	16.287	EPSD	TCGA;ICGC;COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	P28749	RBL1	P24941	CDK2	S1041	R1045C	1045	Missense	distal	4	no	16.162	15.535	EPSD	TCGA;ICGC;COSMIC;CCLE	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	P13051	UNG	P24941	CDK2	S12	P13H	13	Missense	proximal	1	no	13.559	6.800	PhosphoSitePlus;EPSD	TCGA;ICGC;COSMIC	8.148	Loss
CMGC_CDK_CDK2_CDK2_ST	P13051	UNG	P24941	CDK2	S12	F10V	10	Missense	proximal	-2	no	13.559	14.022	PhosphoSitePlus;EPSD	TCGA;ICGC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	P13051	UNG	P24941	CDK2	S14	P13H	13	Missense	proximal	-1	no	14.457	14.576	EPSD	TCGA;ICGC;COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	P13051	UNG	P24941	CDK2	S14	F10V	10	Missense	distal	-4	no	14.457	15.016	EPSD	TCGA;ICGC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	P13051	UNG	P24941	CDK2	T60	G59R	59	Missense	proximal	-1	no	14.936	14.458	EPSD;PhosphoSitePlus	TCGA;COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	P13051	UNG	P24941	CDK2	S64	G59R	59	Missense	distal	-5	no	12.611	12.579	EPSD;PhosphoSitePlus	TCGA;COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	P13051	UNG	P24941	CDK2	S279	P278S	278	Missense	proximal	-1	no	13.966	13.495	EPSD	TCGA;COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	P13051	UNG	P24941	CDK2	S279	G286R	286	Missense	distal	7	no	13.966	13.786	EPSD	TCGA	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	Q92547	TOPBP1	P24941	CDK2	S308	R309P	309	Missense	proximal	1	no	4.584	14.383	EPSD	TCGA;ICGC;COSMIC	8.148	Gain
CMGC_CDK_CDK2_CDK2_ST	Q92547	TOPBP1	P24941	CDK2	S370	I364T	364	Missense	distal	-6	no	10.388	10.386	EPSD	TCGA;ICGC;COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	Q92547	TOPBP1	P24941	CDK2	S370	R363W	363	Missense	distal	-7	no	10.388	10.559	EPSD	TCGA;ICGC;COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	Q92547	TOPBP1	P24941	CDK2	S370	R363Q	363	Missense	distal	-7	no	10.388	10.002	EPSD	TCGA;ICGC;COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	Q92547	TOPBP1	P24941	CDK2	S734	T727M	727	Missense	distal	-7	no	7.985	8.488	EPSD	TCGA;ICGC;COSMIC	8.148	Gain
CMGC_CDK_CDK2_CDK2_ST	Q92547	TOPBP1	P24941	CDK2	S734	R730S	730	Missense	distal	-4	no	7.985	8.582	EPSD	TCGA;ICGC;COSMIC	8.148	Gain
CMGC_CDK_CDK2_CDK2_ST	Q92547	TOPBP1	P24941	CDK2	T779	N784S	784	Missense	distal	5	no	11.270	11.066	EPSD	TCGA;ICGC;COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	Q92547	TOPBP1	P24941	CDK2	S853	P859L	859	Missense	distal	6	no	8.475	8.476	EPSD	TCGA;ICGC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	Q92547	TOPBP1	P24941	CDK2	T861	V866F	866	Missense	distal	5	no	11.412	11.663	EPSD	TCGA;ICGC;COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	Q92547	TOPBP1	P24941	CDK2	T861	T861M	861	Missense	central	0	yes	11.412	0.000	EPSD	TCGA;ICGC;COSMIC	8.148	Loss
CMGC_CDK_CDK2_CDK2_ST	Q92547	TOPBP1	P24941	CDK2	T861	P859L	859	Missense	proximal	-2	no	11.412	11.188	EPSD	TCGA;ICGC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	Q92547	TOPBP1	P24941	CDK2	S888	Q890E	890	Missense	proximal	2	no	12.388	12.425	EPSD	TCGA;ICGC;COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	Q92547	TOPBP1	P24941	CDK2	S888	A887S	887	Missense	proximal	-1	no	12.388	12.187	EPSD	TCGA;ICGC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	Q92547	TOPBP1	P24941	CDK2	S888	L891P	891	Missense	distal	3	no	12.388	12.771	EPSD	TCGA;ICGC;COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	Q92547	TOPBP1	P24941	CDK2	S888	A894V	894	Missense	distal	6	no	12.388	12.390	EPSD	TCGA;ICGC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	Q92547	TOPBP1	P24941	CDK2	S1093	L1094P	1094	Missense	proximal	1	no	4.253	14.074	EPSD	TCGA;ICGC;COSMIC	8.148	Gain
CMGC_CDK_CDK2_CDK2_ST	Q92547	TOPBP1	P24941	CDK2	T1221	I1215M	1215	Missense	distal	-6	no	17.366	17.371	EPSD	TCGA;ICGC;COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	Q92547	TOPBP1	P24941	CDK2	T1231	I1237V	1237	Missense	distal	6	no	13.097	13.095	EPSD	TCGA;ICGC;COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	Q92547	TOPBP1	P24941	CDK2	T1501	L1503F	1503	Missense	proximal	2	no	8.246	8.604	EPSD	TCGA	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	Q92547	TOPBP1	P24941	CDK2	S1504	L1503F	1503	Missense	proximal	-1	no	7.811	8.776	EPSD	TCGA	8.148	Gain
CMGC_CDK_CDK2_CDK2_ST	Q92785	DPF2	P24941	CDK2	T176	R179H	179	Missense	distal	3	no	16.849	16.153	PhosphoSitePlus	TCGA;ICGC;COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	Q92785	DPF2	P24941	CDK2	T176	R179C	179	Missense	distal	3	no	16.849	10.485	PhosphoSitePlus	TCGA;ICGC;COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	Q92785	DPF2	P24941	CDK2	T176	T176I	176	Missense	central	0	yes	16.849	0.000	PhosphoSitePlus	TCGA;ICGC;COSMIC	8.148	Loss
CMGC_CDK_CDK2_CDK2_ST	Q92785	DPF2	P24941	CDK2	T248	E255Q	255	Missense	distal	7	no	15.200	15.001	EPSD	TCGA;ICGC;COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	Q92785	DPF2	P24941	CDK2	T248	S254Y	254	Missense	distal	6	no	15.200	15.191	EPSD	TCGA;ICGC;COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	Q92785	DPF2	P24941	CDK2	T248	P249S	249	Missense	proximal	1	no	15.200	3.935	EPSD	TCGA;ICGC;COSMIC	8.148	Loss
CMGC_CDK_CDK2_CDK2_ST	Q92785	DPF2	P24941	CDK2	T248	T248I	248	Missense	central	0	yes	15.200	0.000	EPSD	TCGA;ICGC	8.148	Loss
CMGC_CDK_CDK2_CDK2_ST	Q92785	DPF2	P24941	CDK2	T248	E255G	255	Missense	distal	7	no	15.200	15.826	EPSD	TCGA;ICGC;COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	Q92785	DPF2	P24941	CDK2	T310	T310I	310	Missense	central	0	yes	12.339	0.000	EPSD	TCGA;ICGC;COSMIC	8.148	Loss
CMGC_CDK_CDK2_CDK2_ST	Q92785	DPF2	P24941	CDK2	T310	S305F	305	Missense	distal	-5	no	12.339	12.456	EPSD	TCGA;ICGC;COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	Q92785	DPF2	P24941	CDK2	T310	A315V	315	Missense	distal	5	no	12.339	12.296	EPSD	TCGA;ICGC;COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	Q92785	DPF2	P24941	CDK2	T358	M354I	354	Missense	distal	-4	no	11.160	11.757	EPSD	TCGA;COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	Q9UEY8	ADD3	P24941	CDK2	T12	A5V	5	Missense	distal	-7	no	13.195	13.050	EPSD	TCGA;COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	Q9UEY8	ADD3	P24941	CDK2	T12	T11S	11	Missense	proximal	-1	no	13.195	12.987	EPSD	TCGA;ICGC;COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	Q9UEY8	ADD3	P24941	CDK2	T12	P13S	13	Missense	proximal	1	no	13.195	1.929	EPSD	TCGA;ICGC;COSMIC	8.148	Loss
CMGC_CDK_CDK2_CDK2_ST	Q9UEY8	ADD3	P24941	CDK2	S42	L45P	45	Missense	distal	3	no	14.917	15.300	EPSD	TCGA;ICGC;COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	Q9UEY8	ADD3	P24941	CDK2	S64	R68W	68	Missense	distal	4	no	13.449	13.089	EPSD	TCGA;ICGC;COSMIC;CCLE	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	Q9UEY8	ADD3	P24941	CDK2	S64	Q60E	60	Missense	distal	-4	no	13.449	13.897	EPSD	TCGA;ICGC;COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	Q9UEY8	ADD3	P24941	CDK2	S64	A66V	66	Missense	proximal	2	no	13.449	13.547	EPSD	TCGA;ICGC;COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	Q9UEY8	ADD3	P24941	CDK2	S108	N101S	101	Missense	distal	-7	no	11.625	11.526	EPSD	TCGA;ICGC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	Q9UEY8	ADD3	P24941	CDK2	T117	P123H	123	Missense	distal	6	no	13.273	13.268	EPSD	TCGA;ICGC;COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	Q9UEY8	ADD3	P24941	CDK2	S360	Q362K	362	Missense	proximal	2	no	11.189	10.989	EPSD	TCGA;ICGC;COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	Q9UEY8	ADD3	P24941	CDK2	S360	G359D	359	Missense	proximal	-1	no	11.189	10.896	EPSD	TCGA;ICGC;COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	Q9UEY8	ADD3	P24941	CDK2	S423	D418N	418	Missense	distal	-5	no	17.772	17.733	PhosphoSitePlus	TCGA;ICGC;COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	Q9UEY8	ADD3	P24941	CDK2	S461	T467M	467	Missense	distal	6	no	13.088	13.061	EPSD	TCGA;ICGC;COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	Q9UEY8	ADD3	P24941	CDK2	S461	S455Y	455	Missense	distal	-6	no	13.088	13.089	EPSD	TCGA;ICGC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	Q9UEY8	ADD3	P24941	CDK2	S461	R463Q	463	Missense	proximal	2	no	13.088	12.988	EPSD	TCGA;ICGC;COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	Q9UEY8	ADD3	P24941	CDK2	T481	G480E	480	Missense	proximal	-1	no	15.493	15.230	EPSD	TCGA;ICGC;COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	Q9UEY8	ADD3	P24941	CDK2	T481	D487V	487	Missense	distal	6	no	15.493	15.507	EPSD	TCGA;ICGC;COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	Q9UEY8	ADD3	P24941	CDK2	S600	I594F	594	Missense	distal	-6	no	12.579	12.581	EPSD	TCGA;ICGC;COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	Q9UEY8	ADD3	P24941	CDK2	S600	S600L	600	Missense	central	0	yes	12.579	0.000	EPSD	TCGA;ICGC;COSMIC	8.148	Loss
CMGC_CDK_CDK2_CDK2_ST	Q9UEY8	ADD3	P24941	CDK2	S600	P601L	601	Missense	proximal	1	no	12.579	2.758	EPSD	TCGA;ICGC;COSMIC	8.148	Loss
CMGC_CDK_CDK2_CDK2_ST	Q9UEY8	ADD3	P24941	CDK2	S664	E659K	659	Missense	distal	-5	no	14.352	14.318	EPSD	TCGA;ICGC;COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	Q9UEY8	ADD3	P24941	CDK2	S673	E675D	675	Missense	proximal	2	no	13.022	12.922	EPSD	TCGA;ICGC;COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	Q9UEY8	ADD3	P24941	CDK2	S677	E675D	675	Missense	proximal	-2	no	15.279	16.260	EPSD	TCGA;ICGC;COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	Q9UEY8	ADD3	P24941	CDK2	S677	K684N	684	Missense	distal	7	no	15.279	15.472	EPSD	TCGA	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	Q9UEY8	ADD3	P24941	CDK2	S681	E675D	675	Missense	distal	-6	no	16.946	16.941	EPSD	TCGA;ICGC;COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	Q9UEY8	ADD3	P24941	CDK2	S681	K686N	686	Missense	distal	5	no	16.946	17.103	EPSD	TCGA;ICGC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	Q9UEY8	ADD3	P24941	CDK2	S681	K684N	684	Missense	distal	3	no	16.946	13.675	EPSD	TCGA	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	Q9UEY8	ADD3	P24941	CDK2	T691	K686N	686	Missense	distal	-5	no	14.131	14.147	EPSD	TCGA;ICGC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	Q9UEY8	ADD3	P24941	CDK2	T691	K684N	684	Missense	distal	-7	no	14.131	14.096	EPSD	TCGA	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	Q0VD86	INCA1	P24941	CDK2	S23	R18K	18	Missense	distal	-5	no	14.291	14.247	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	Q0VD86	INCA1	P24941	CDK2	T182	R179C	179	Missense	distal	-3	no	16.451	16.365	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	Q0VD86	INCA1	P24941	CDK2	T182	R179S	179	Missense	distal	-3	no	16.451	16.358	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	P61978	HNRNPK	P24941	CDK2	S116	P117L	117	Missense	proximal	1	no	14.915	5.094	EPSD	TCGA;ICGC	8.148	Loss
CMGC_CDK_CDK2_CDK2_ST	P61978	HNRNPK	P24941	CDK2	S216	R221H	221	Missense	distal	5	no	19.794	19.765	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	P61978	HNRNPK	P24941	CDK2	S284	M283V	283	Missense	proximal	-1	no	18.787	17.694	PhosphoSitePlus;EPSD	TCGA;ICGC;COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	P61978	HNRNPK	P24941	CDK2	S302	R305Q	305	Missense	distal	3	no	8.160	6.416	EPSD	TCGA;ICGC;COSMIC	8.148	Loss
CMGC_CDK_CDK2_CDK2_ST	P61978	HNRNPK	P24941	CDK2	S302	R305W	305	Missense	distal	3	no	8.160	5.520	EPSD	TCGA;ICGC;COSMIC	8.148	Loss
CMGC_CDK_CDK2_CDK2_ST	P61978	HNRNPK	P24941	CDK2	S302	A304V	304	Missense	proximal	2	no	8.160	8.258	EPSD	TCGA;ICGC;COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	P61978	HNRNPK	P24941	CDK2	S302	G298S	298	Missense	distal	-4	no	8.160	8.832	EPSD	TCGA;ICGC;COSMIC;CCLE	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	P61978	HNRNPK	P24941	CDK2	S353	S355L	355	Missense	proximal	2	no	19.413	19.240	EPSD	TCGA;ICGC;COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	P61978	HNRNPK	P24941	CDK2	S353	E356D	356	Missense	distal	3	no	19.413	16.978	EPSD	TCGA;ICGC;COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	P61978	HNRNPK	P24941	CDK2	S353	E356A	356	Missense	distal	3	no	19.413	18.279	EPSD	TCGA;ICGC;COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	P61978	HNRNPK	P24941	CDK2	S430	E428D	428	Missense	proximal	-2	no	7.383	8.364	EPSD	TCGA;ICGC;COSMIC	8.148	Gain
CMGC_CDK_CDK2_CDK2_ST	P42677	RPS27	P24941	CDK2	S11	E14A	14	Missense	distal	3	no	11.693	10.559	EPSD	TCGA;ICGC;COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	P42677	RPS27	P24941	CDK2	S11	D6N	6	Missense	distal	-5	no	11.693	11.655	EPSD	TCGA;ICGC;COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	P42677	RPS27	P24941	CDK2	S11	S11F	11	Missense	central	0	yes	11.693	0.000	EPSD	TCGA;ICGC;COSMIC	8.148	Loss
CMGC_CDK_CDK2_CDK2_ST	P42677	RPS27	P24941	CDK2	S11	R17S	17	Missense	distal	6	no	11.693	11.711	EPSD	TCGA;ICGC;COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	P42677	RPS27	P24941	CDK2	S27	F32V	32	Missense	distal	5	no	15.410	15.159	PhosphoSitePlus	TCGA;ICGC;COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	O00311	CDC7	P24941	CDK2	S16	F22S	22	Missense	distal	6	no	15.438	15.457	EPSD	TCGA;ICGC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	O00311	CDC7	P24941	CDK2	S302	E301D	301	Missense	proximal	-1	no	13.608	13.578	EPSD	TCGA;COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	O00311	CDC7	P24941	CDK2	S302	H295Y	295	Missense	distal	-7	no	13.608	13.610	EPSD	TCGA;COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	O00311	CDC7	P24941	CDK2	S302	V305L	305	Missense	distal	3	no	13.608	12.616	EPSD	TCGA;COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	O00311	CDC7	P24941	CDK2	S302	S297F	297	Missense	distal	-5	no	13.608	13.724	EPSD	TCGA;COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	O00311	CDC7	P24941	CDK2	T472	S470Y	470	Missense	proximal	-2	no	12.177	12.264	EPSD	TCGA;ICGC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	P24941	CDK2	P24941	CDK2	T160	V163M	163	Missense	distal	3	no	12.187	11.339	PhosphoSitePlus	TCGA;ICGC;COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	P24941	CDK2	P24941	CDK2	T160	P155H	155	Missense	distal	-5	no	12.187	12.234	PhosphoSitePlus	TCGA	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	P24941	CDK2	P24941	CDK2	T221	D223Y	223	Missense	proximal	2	no	15.212	15.273	EPSD	TCGA;GDSC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	Q14980	NUMA1	P24941	CDK2	S77	R72Q	72	Missense	distal	-5	no	10.824	10.777	EPSD	TCGA;ICGC;COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	Q14980	NUMA1	P24941	CDK2	S77	E79Q	79	Missense	proximal	2	no	10.824	10.786	EPSD	TCGA;ICGC;COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	Q14980	NUMA1	P24941	CDK2	S77	H74R	74	Missense	distal	-3	no	10.824	10.866	EPSD	TCGA;ICGC;COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	Q14980	NUMA1	P24941	CDK2	S112	H105N	105	Missense	distal	-7	no	11.332	11.128	EPSD	TCGA;ICGC;COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	Q14980	NUMA1	P24941	CDK2	S112	F119L	119	Missense	distal	7	no	11.332	10.661	EPSD	TCGA;ICGC;COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	Q14980	NUMA1	P24941	CDK2	S169	E167G	167	Missense	proximal	-2	no	9.491	9.863	EPSD	TCGA;ICGC;COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	Q14980	NUMA1	P24941	CDK2	S200	S198L	198	Missense	proximal	-2	no	14.758	15.185	EPSD	TCGA;ICGC;COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	Q14980	NUMA1	P24941	CDK2	S200	P204H	204	Missense	distal	4	no	14.758	14.520	EPSD	TCGA;ICGC;COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	Q14980	NUMA1	P24941	CDK2	S200	D207N	207	Missense	distal	7	no	14.758	13.978	EPSD	TCGA;ICGC;COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	Q14980	NUMA1	P24941	CDK2	S203	S198L	198	Missense	distal	-5	no	14.035	14.091	EPSD	TCGA;ICGC;COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	Q14980	NUMA1	P24941	CDK2	S203	P204H	204	Missense	proximal	1	no	14.035	7.276	EPSD	TCGA;ICGC;COSMIC	8.148	Loss
CMGC_CDK_CDK2_CDK2_ST	Q14980	NUMA1	P24941	CDK2	S203	D207N	207	Missense	distal	4	no	14.035	14.080	EPSD	TCGA;ICGC;COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	Q14980	NUMA1	P24941	CDK2	T211	P212L	212	Missense	proximal	1	no	14.360	4.539	EPSD	TCGA;ICGC;COSMIC	8.148	Loss
CMGC_CDK_CDK2_CDK2_ST	Q14980	NUMA1	P24941	CDK2	T211	P204H	204	Missense	distal	-7	no	14.360	14.483	EPSD	TCGA;ICGC;COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	Q14980	NUMA1	P24941	CDK2	T211	D207N	207	Missense	distal	-4	no	14.360	13.971	EPSD	TCGA;ICGC;COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	Q14980	NUMA1	P24941	CDK2	S271	A269T	269	Missense	proximal	-2	no	13.707	13.657	EPSD	TCGA;ICGC;COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	Q14980	NUMA1	P24941	CDK2	S271	K276N	276	Missense	distal	5	no	13.707	13.864	EPSD	TCGA;ICGC;COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	Q14980	NUMA1	P24941	CDK2	S861	E854K	854	Missense	distal	-7	no	8.445	8.308	EPSD	TCGA;ICGC;COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	Q14980	NUMA1	P24941	CDK2	S861	G858A	858	Missense	distal	-3	no	8.445	8.283	EPSD	TCGA;ICGC;COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	Q14980	NUMA1	P24941	CDK2	S1225	L1226P	1226	Missense	proximal	1	no	4.385	14.206	EPSD	TCGA;ICGC;COSMIC	8.148	Gain
CMGC_CDK_CDK2_CDK2_ST	Q14980	NUMA1	P24941	CDK2	T1733	E1730K	1730	Missense	distal	-3	no	11.679	11.464	EPSD	TCGA;COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	Q14980	NUMA1	P24941	CDK2	T1733	S1736G	1736	Missense	distal	3	no	11.679	11.544	EPSD	TCGA;COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	Q14980	NUMA1	P24941	CDK2	S1757	S1760C	1760	Missense	distal	3	no	11.817	7.137	EPSD	TCGA;COSMIC	8.148	Loss
CMGC_CDK_CDK2_CDK2_ST	Q14980	NUMA1	P24941	CDK2	S1757	P1764T	1764	Missense	distal	7	no	11.817	11.513	EPSD	TCGA;COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	Q14980	NUMA1	P24941	CDK2	T1776	E1771G	1771	Missense	distal	-5	no	14.456	14.499	PhosphoSitePlus	TCGA	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	Q14980	NUMA1	P24941	CDK2	T1776	R1781W	1781	Missense	distal	5	no	14.456	14.623	PhosphoSitePlus	TCGA;COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	Q14980	NUMA1	P24941	CDK2	T1776	R1781Q	1781	Missense	distal	5	no	14.456	14.310	PhosphoSitePlus	TCGA;COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	Q14980	NUMA1	P24941	CDK2	S1782	R1781W	1781	Missense	proximal	-1	no	9.100	9.654	EPSD	TCGA;COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	Q14980	NUMA1	P24941	CDK2	S1782	R1781Q	1781	Missense	proximal	-1	no	9.100	8.222	EPSD	TCGA;COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	Q14980	NUMA1	P24941	CDK2	S1800	V1796I	1796	Missense	distal	-4	no	11.818	11.715	EPSD	TCGA;COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	Q14980	NUMA1	P24941	CDK2	S1887	G1890R	1890	Missense	distal	3	no	6.885	8.704	EPSD	TCGA;COSMIC	8.148	Gain
CMGC_CDK_CDK2_CDK2_ST	Q14980	NUMA1	P24941	CDK2	T2015	R2012H	2012	Missense	distal	-3	no	12.993	12.951	EPSD	TCGA;COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	Q14980	NUMA1	P24941	CDK2	T2015	R2019Q	2019	Missense	distal	4	no	12.993	13.175	EPSD	TCGA	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	Q14980	NUMA1	P24941	CDK2	T2055	S2051N	2051	Missense	distal	-4	no	14.354	14.137	EPSD	TCGA;COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	Q14980	NUMA1	P24941	CDK2	T2055	P2056S	2056	Missense	proximal	1	no	14.354	3.088	EPSD	TCGA	8.148	Loss
CMGC_CDK_CDK2_CDK2_ST	Q14980	NUMA1	P24941	CDK2	S2077	K2075Q	2075	Missense	proximal	-2	no	11.730	11.677	EPSD	TCGA;COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	Q14980	NUMA1	P24941	CDK2	S2077	R2081C	2081	Missense	distal	4	no	11.730	11.103	EPSD	TCGA;COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	Q14980	NUMA1	P24941	CDK2	S2087	R2081C	2081	Missense	distal	-6	no	12.911	12.914	EPSD	TCGA;COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	Q14980	NUMA1	P24941	CDK2	T2106	A2105V	2105	Missense	proximal	-1	no	13.905	14.132	EPSD	TCGA;COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	Q14980	NUMA1	P24941	CDK2	T2106	A2102V	2102	Missense	distal	-4	no	13.905	13.916	EPSD	TCGA;COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	Q15717	ELAVL1	P24941	CDK2	S202	H201Q	201	Missense	proximal	-1	no	15.691	15.264	PhosphoSitePlus	TCGA;ICGC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	Q15717	ELAVL1	P24941	CDK2	S221	R217T	217	Missense	distal	-4	no	13.732	14.142	EPSD	TCGA;ICGC;COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	Q15717	ELAVL1	P24941	CDK2	S221	D226N	226	Missense	distal	5	no	13.732	13.662	EPSD	TCGA;ICGC;COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	P24864	CCNE1	P24941	CDK2	T77	D83N	83	Missense	distal	6	no	17.699	17.718	EPSD	TCGA;ICGC;COSMIC;GDSC;CCLE	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	P24864	CCNE1	P24941	CDK2	T77	D83G	83	Missense	distal	6	no	17.699	17.703	EPSD	TCGA;ICGC;COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	P24864	CCNE1	P24941	CDK2	S90	D83N	83	Missense	distal	-7	no	8.750	8.427	EPSD	TCGA;ICGC;COSMIC;GDSC;CCLE	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	P24864	CCNE1	P24941	CDK2	S90	D83G	83	Missense	distal	-7	no	8.750	8.833	EPSD	TCGA;ICGC;COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	P24864	CCNE1	P24941	CDK2	S103	R101K	101	Missense	proximal	-2	no	16.109	16.830	EPSD	TCGA;ICGC;COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	P24864	CCNE1	P24941	CDK2	S387	R385T	385	Missense	proximal	-2	no	13.244	14.446	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	P24864	CCNE1	P24941	CDK2	S387	R385S	385	Missense	proximal	-2	no	13.244	13.829	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	P24864	CCNE1	P24941	CDK2	S387	A386S	386	Missense	proximal	-1	no	13.244	13.043	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	P24864	CCNE1	P24941	CDK2	T395	T395I	395	Missense	central	0	yes	13.881	0.000	PhosphoSitePlus;EPSD	TCGA;ICGC;COSMIC	8.148	Loss
CMGC_CDK_CDK2_CDK2_ST	P24864	CCNE1	P24941	CDK2	T395	P396L	396	Missense	proximal	1	no	13.881	4.060	PhosphoSitePlus;EPSD	TCGA;ICGC;COSMIC	8.148	Loss
CMGC_CDK_CDK2_CDK2_ST	P24864	CCNE1	P24941	CDK2	S399	T395I	395	Missense	distal	-4	no	10.890	10.572	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	P24864	CCNE1	P24941	CDK2	S399	P396L	396	Missense	distal	-3	no	10.890	10.819	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	Q14103	HNRNPD	P24941	CDK2	T47	G50E	50	Missense	distal	3	no	7.709	8.432	EPSD	TCGA;ICGC;COSMIC	8.148	Gain
CMGC_CDK_CDK2_CDK2_ST	Q14103	HNRNPD	P24941	CDK2	S118	K119R	119	Missense	proximal	1	no	1.276	9.128	EPSD	TCGA;ICGC;COSMIC	8.148	Gain
CMGC_CDK_CDK2_CDK2_ST	Q14103	HNRNPD	P24941	CDK2	T134	T127I	127	Missense	distal	-7	no	8.112	8.309	EPSD	TCGA;ICGC;COSMIC	8.148	Gain
CMGC_CDK_CDK2_CDK2_ST	Q14103	HNRNPD	P24941	CDK2	T134	R138S	138	Missense	distal	4	no	8.112	8.246	EPSD	TCGA;ICGC	8.148	Gain
CMGC_CDK_CDK2_CDK2_ST	Q14103	HNRNPD	P24941	CDK2	S190	E196Q	196	Missense	distal	6	no	12.015	12.023	EPSD	TCGA;ICGC;COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	Q14103	HNRNPD	P24941	CDK2	S190	K183N	183	Missense	distal	-7	no	12.015	11.981	EPSD	TCGA;ICGC;COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	Q14103	HNRNPD	P24941	CDK2	S190	I184N	184	Missense	distal	-6	no	12.015	12.012	EPSD	TCGA;ICGC;COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	Q14103	HNRNPD	P24941	CDK2	T193	E196Q	196	Missense	distal	3	no	15.027	14.380	PhosphoSitePlus	TCGA;ICGC;COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	Q14103	HNRNPD	P24941	CDK2	T193	I198V	198	Missense	distal	5	no	15.027	14.901	PhosphoSitePlus	TCGA;ICGC;COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	P31350	RRM2	P24941	CDK2	S377	M375I	375	Missense	proximal	-2	no	12.856	14.786	EPSD	TCGA;COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	P16949	STMN1	P24941	CDK2	S25	S31Y	31	Missense	distal	6	no	14.872	14.863	PhosphoSitePlus;EPSD	TCGA;COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	P16949	STMN1	P24941	CDK2	S25	S28P	28	Missense	distal	3	no	14.872	14.838	PhosphoSitePlus;EPSD	TCGA;ICGC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	P16949	STMN1	P24941	CDK2	S25	K29I	29	Missense	distal	4	no	14.872	14.442	PhosphoSitePlus;EPSD	TCGA;ICGC;COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	P16949	STMN1	P24941	CDK2	S38	S31Y	31	Missense	distal	-7	no	17.348	17.654	EPSD;PhosphoSitePlus	TCGA;COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	P16949	STMN1	P24941	CDK2	S38	P39S	39	Missense	proximal	1	no	17.348	6.082	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	8.148	Loss
CMGC_CDK_CDK2_CDK2_ST	P12956	XRCC6	P24941	CDK2	S51	E54K	54	Missense	distal	3	no	7.812	9.897	EPSD	TCGA;ICGC;COSMIC	8.148	Gain
CMGC_CDK_CDK2_CDK2_ST	P12956	XRCC6	P24941	CDK2	T58	E54K	54	Missense	distal	-4	no	10.563	10.251	EPSD	TCGA;ICGC;COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	P12956	XRCC6	P24941	CDK2	T428	G431C	431	Missense	distal	3	no	13.162	8.618	EPSD	TCGA;ICGC;COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	P12956	XRCC6	P24941	CDK2	T428	P430A	430	Missense	proximal	2	no	13.162	13.187	EPSD	TCGA;ICGC;COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	P12956	XRCC6	P24941	CDK2	T428	T428N	428	Missense	central	0	yes	13.162	0.000	EPSD	TCGA;ICGC;COSMIC	8.148	Loss
CMGC_CDK_CDK2_CDK2_ST	P12956	XRCC6	P24941	CDK2	T455	P456A	456	Missense	proximal	1	no	13.191	-1.212	PhosphoSitePlus	TCGA;ICGC;COSMIC	8.148	Loss
CMGC_CDK_CDK2_CDK2_ST	P12956	XRCC6	P24941	CDK2	T455	P456L	456	Missense	proximal	1	no	13.191	3.370	PhosphoSitePlus	TCGA;ICGC;COSMIC	8.148	Loss
CMGC_CDK_CDK2_CDK2_ST	P12956	XRCC6	P24941	CDK2	S550	S550P	550	Missense	central	0	yes	10.327	0.000	EPSD	TCGA;ICGC	8.148	Loss
CMGC_CDK_CDK2_CDK2_ST	P12956	XRCC6	P24941	CDK2	S592	C585F	585	Missense	distal	-7	no	11.485	11.586	EPSD	TCGA;ICGC;COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	P52948	NUP98	P24941	CDK2	S839	S839L	839	Missense	central	0	yes	15.080	0.000	EPSD	TCGA;ICGC;COSMIC	8.148	Loss
CMGC_CDK_CDK2_CDK2_ST	P52948	NUP98	P24941	CDK2	T1070	P1071S	1071	Missense	proximal	1	no	12.937	1.671	EPSD	TCGA;ICGC;COSMIC	8.148	Loss
CMGC_CDK_CDK2_CDK2_ST	P52948	NUP98	P24941	CDK2	T1217	L1219F	1219	Missense	proximal	2	no	12.791	13.148	EPSD	TCGA;ICGC;COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	P62913	RPL11	P24941	CDK2	S29	L22V	22	Missense	distal	-7	no	10.080	10.094	EPSD	TCGA	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	P62913	RPL11	P24941	CDK2	S29	L33M	33	Missense	distal	4	no	10.080	9.547	EPSD	TCGA;ICGC;COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	P62913	RPL11	P24941	CDK2	T47	P48R	48	Missense	proximal	1	no	14.735	4.936	PhosphoSitePlus	TCGA	8.148	Loss
CMGC_CDK_CDK2_CDK2_ST	Q9C0C2	TNKS1BP1	P24941	CDK2	T27	E30K	30	Missense	distal	3	no	8.113	10.199	EPSD	TCGA;ICGC;COSMIC	8.148	Gain
CMGC_CDK_CDK2_CDK2_ST	Q9C0C2	TNKS1BP1	P24941	CDK2	S178	R181H	181	Missense	distal	3	no	15.991	15.294	EPSD	TCGA;ICGC;GDSC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	Q9C0C2	TNKS1BP1	P24941	CDK2	S178	R181C	181	Missense	distal	3	no	15.991	9.627	EPSD	TCGA;ICGC;COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	Q9C0C2	TNKS1BP1	P24941	CDK2	S228	C232R	232	Missense	distal	4	no	13.603	14.230	EPSD	TCGA;ICGC;COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	Q9C0C2	TNKS1BP1	P24941	CDK2	S228	E235Q	235	Missense	distal	7	no	13.603	13.405	EPSD	TCGA;ICGC;COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	Q9C0C2	TNKS1BP1	P24941	CDK2	T239	C232R	232	Missense	distal	-7	no	12.977	13.050	EPSD	TCGA;ICGC;COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	Q9C0C2	TNKS1BP1	P24941	CDK2	T239	E235Q	235	Missense	distal	-4	no	12.977	12.528	EPSD	TCGA;ICGC;COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	Q9C0C2	TNKS1BP1	P24941	CDK2	T239	S244I	244	Missense	distal	5	no	12.977	13.171	EPSD	TCGA;ICGC;COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	Q9C0C2	TNKS1BP1	P24941	CDK2	S260	S261P	261	Missense	proximal	1	no	1.598	12.863	EPSD	TCGA;ICGC	8.148	Gain
CMGC_CDK_CDK2_CDK2_ST	Q9C0C2	TNKS1BP1	P24941	CDK2	S275	E281D	281	Missense	distal	6	no	13.397	13.385	EPSD	TCGA;ICGC;COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	Q9C0C2	TNKS1BP1	P24941	CDK2	S287	E281D	281	Missense	distal	-6	no	14.401	14.396	EPSD	TCGA;ICGC;COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	Q9C0C2	TNKS1BP1	P24941	CDK2	S301	P306L	306	Missense	distal	5	no	14.177	14.217	EPSD	TCGA;ICGC;COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	Q9C0C2	TNKS1BP1	P24941	CDK2	S311	P306L	306	Missense	distal	-5	no	13.207	13.219	EPSD	TCGA;ICGC;COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	Q9C0C2	TNKS1BP1	P24941	CDK2	S329	P330L	330	Missense	proximal	1	no	11.667	1.846	EPSD	TCGA;ICGC;COSMIC	8.148	Loss
CMGC_CDK_CDK2_CDK2_ST	Q9C0C2	TNKS1BP1	P24941	CDK2	S329	A333T	333	Missense	distal	4	no	11.667	11.910	EPSD	TCGA;ICGC;COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	Q9C0C2	TNKS1BP1	P24941	CDK2	T335	P330L	330	Missense	distal	-5	no	12.229	12.241	EPSD	TCGA;ICGC;COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	Q9C0C2	TNKS1BP1	P24941	CDK2	T335	A333T	333	Missense	proximal	-2	no	12.229	12.179	EPSD	TCGA;ICGC;COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	Q9C0C2	TNKS1BP1	P24941	CDK2	T351	D345G	345	Missense	distal	-6	no	12.218	12.222	EPSD	TCGA;ICGC;CCLE	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	Q9C0C2	TNKS1BP1	P24941	CDK2	S353	E359K	359	Missense	distal	6	no	13.714	13.725	EPSD	TCGA;ICGC;COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	Q9C0C2	TNKS1BP1	P24941	CDK2	S387	P384S	384	Missense	distal	-3	no	14.619	14.714	EPSD	TCGA;ICGC;COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	Q9C0C2	TNKS1BP1	P24941	CDK2	S435	D439G	439	Missense	distal	4	no	14.171	14.116	EPSD	TCGA;ICGC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	Q9C0C2	TNKS1BP1	P24941	CDK2	S494	W490C	490	Missense	distal	-4	no	13.077	13.326	EPSD	TCGA;ICGC;COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	Q9C0C2	TNKS1BP1	P24941	CDK2	S494	P496L	496	Missense	proximal	2	no	13.077	12.970	EPSD	TCGA;ICGC;COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	Q9C0C2	TNKS1BP1	P24941	CDK2	S494	V489L	489	Missense	distal	-5	no	13.077	13.058	EPSD	TCGA;ICGC;COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	Q9C0C2	TNKS1BP1	P24941	CDK2	S498	P496L	496	Missense	proximal	-2	no	15.064	14.840	EPSD	TCGA;ICGC;COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	Q9C0C2	TNKS1BP1	P24941	CDK2	S498	E505V	505	Missense	distal	7	no	15.064	15.278	EPSD	TCGA;ICGC;COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	Q9C0C2	TNKS1BP1	P24941	CDK2	T578	G577C	577	Missense	proximal	-1	no	12.772	11.597	EPSD	TCGA;ICGC;COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	Q9C0C2	TNKS1BP1	P24941	CDK2	T578	P571L	571	Missense	distal	-7	no	12.772	12.778	EPSD	TCGA;ICGC;COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	Q9C0C2	TNKS1BP1	P24941	CDK2	S601	P604R	604	Missense	distal	3	no	14.290	16.009	EPSD	TCGA;ICGC;COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	Q9C0C2	TNKS1BP1	P24941	CDK2	S601	P602H	602	Missense	proximal	1	no	14.290	7.532	EPSD	TCGA;ICGC;COSMIC	8.148	Loss
CMGC_CDK_CDK2_CDK2_ST	Q9C0C2	TNKS1BP1	P24941	CDK2	S672	P676A	676	Missense	distal	4	no	10.728	10.767	EPSD	TCGA;ICGC;COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	Q9C0C2	TNKS1BP1	P24941	CDK2	S672	P676S	676	Missense	distal	4	no	10.728	10.741	EPSD	TCGA;ICGC;COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	Q9C0C2	TNKS1BP1	P24941	CDK2	S691	G697R	697	Missense	distal	6	no	14.996	14.991	PhosphoSitePlus	TCGA;ICGC;COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	Q9C0C2	TNKS1BP1	P24941	CDK2	S691	G698S	698	Missense	distal	7	no	14.996	14.174	PhosphoSitePlus	TCGA;ICGC;COSMIC;GDSC;CCLE	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	Q9C0C2	TNKS1BP1	P24941	CDK2	S744	P738S	738	Missense	distal	-6	no	15.761	15.760	EPSD	TCGA;ICGC;COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	Q9C0C2	TNKS1BP1	P24941	CDK2	S744	G751A	751	Missense	distal	7	no	15.761	15.476	EPSD	TCGA;ICGC;COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	Q9C0C2	TNKS1BP1	P24941	CDK2	S744	G751C	751	Missense	distal	7	no	15.761	15.732	EPSD	TCGA;ICGC;COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	Q9C0C2	TNKS1BP1	P24941	CDK2	S936	R943W	943	Missense	distal	7	no	8.067	8.466	EPSD	TCGA;ICGC;COSMIC	8.148	Gain
CMGC_CDK_CDK2_CDK2_ST	Q9C0C2	TNKS1BP1	P24941	CDK2	S987	Q992H	992	Missense	distal	5	no	14.426	14.544	EPSD	TCGA;ICGC;COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	Q9C0C2	TNKS1BP1	P24941	CDK2	S1029	G1025R	1025	Missense	distal	-4	no	14.499	14.574	EPSD	TCGA;ICGC;COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	Q9C0C2	TNKS1BP1	P24941	CDK2	S1029	S1031G	1031	Missense	proximal	2	no	14.499	14.550	EPSD	TCGA;ICGC;COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	Q9C0C2	TNKS1BP1	P24941	CDK2	S1103	R1098Q	1098	Missense	distal	-5	no	14.619	14.572	EPSD	TCGA;ICGC;COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	Q9C0C2	TNKS1BP1	P24941	CDK2	S1103	A1100T	1100	Missense	distal	-3	no	14.619	14.638	EPSD	TCGA;ICGC;COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	Q9C0C2	TNKS1BP1	P24941	CDK2	S1103	Q1106H	1106	Missense	distal	3	no	14.619	15.666	EPSD	TCGA;ICGC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	Q9C0C2	TNKS1BP1	P24941	CDK2	S1138	R1131T	1131	Missense	distal	-7	no	16.195	15.849	EPSD	TCGA;ICGC;COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	Q9C0C2	TNKS1BP1	P24941	CDK2	S1138	S1140C	1140	Missense	proximal	2	no	16.195	16.274	EPSD	TCGA;ICGC;COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	Q9C0C2	TNKS1BP1	P24941	CDK2	S1138	A1135T	1135	Missense	distal	-3	no	16.195	16.214	EPSD	TCGA	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	Q9C0C2	TNKS1BP1	P24941	CDK2	S1138	R1131I	1131	Missense	distal	-7	no	16.195	16.046	EPSD	TCGA;ICGC;COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	Q9C0C2	TNKS1BP1	P24941	CDK2	S1195	L1198M	1198	Missense	distal	3	no	8.103	8.246	EPSD	TCGA;ICGC;COSMIC	8.148	Gain
CMGC_CDK_CDK2_CDK2_ST	Q9C0C2	TNKS1BP1	P24941	CDK2	S1211	P1217L	1217	Missense	distal	6	no	9.185	9.186	EPSD	TCGA;ICGC;COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	Q9C0C2	TNKS1BP1	P24941	CDK2	S1211	G1207S	1207	Missense	distal	-4	no	9.185	9.857	EPSD	TCGA;ICGC;COSMIC;CCLE	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	Q9C0C2	TNKS1BP1	P24941	CDK2	S1211	T1206A	1206	Missense	distal	-5	no	9.185	9.211	EPSD	TCGA;ICGC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	Q9C0C2	TNKS1BP1	P24941	CDK2	S1253	V1255M	1255	Missense	proximal	2	no	8.829	8.917	EPSD	TCGA;ICGC;COSMIC;GDSC;CCLE	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	Q9C0C2	TNKS1BP1	P24941	CDK2	S1253	T1258I	1258	Missense	distal	5	no	8.829	8.947	EPSD	TCGA;ICGC;COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	Q9C0C2	TNKS1BP1	P24941	CDK2	S1253	G1256R	1256	Missense	distal	3	no	8.829	10.648	EPSD	TCGA;ICGC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	Q9C0C2	TNKS1BP1	P24941	CDK2	S1261	V1255M	1255	Missense	distal	-6	no	10.663	10.669	EPSD	TCGA;ICGC;COSMIC;GDSC;CCLE	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	Q9C0C2	TNKS1BP1	P24941	CDK2	S1261	G1262C	1262	Missense	proximal	1	no	10.663	-0.954	EPSD	TCGA;ICGC;COSMIC	8.148	Loss
CMGC_CDK_CDK2_CDK2_ST	Q9C0C2	TNKS1BP1	P24941	CDK2	S1261	T1258I	1258	Missense	distal	-3	no	10.663	10.722	EPSD	TCGA;ICGC;COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	Q9C0C2	TNKS1BP1	P24941	CDK2	S1261	G1256R	1256	Missense	distal	-5	no	10.663	10.630	EPSD	TCGA;ICGC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	Q9C0C2	TNKS1BP1	P24941	CDK2	S1297	P1292S	1292	Missense	distal	-5	no	13.030	12.986	EPSD	TCGA;ICGC;COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	Q9C0C2	TNKS1BP1	P24941	CDK2	S1371	G1377S	1377	Missense	distal	6	no	9.296	9.308	EPSD	TCGA;ICGC;COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	Q9C0C2	TNKS1BP1	P24941	CDK2	S1405	V1401D	1401	Missense	distal	-4	no	7.695	8.270	EPSD	TCGA;ICGC;COSMIC	8.148	Gain
CMGC_CDK_CDK2_CDK2_ST	Q9C0C2	TNKS1BP1	P24941	CDK2	T1430	A1433S	1433	Missense	distal	3	no	7.662	8.208	EPSD	TCGA;ICGC;COSMIC	8.148	Gain
CMGC_CDK_CDK2_CDK2_ST	Q9C0C2	TNKS1BP1	P24941	CDK2	S1439	G1437R	1437	Missense	proximal	-2	no	16.146	15.652	EPSD	TCGA;ICGC;COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	Q9C0C2	TNKS1BP1	P24941	CDK2	S1503	W1507C	1507	Missense	distal	4	no	11.873	11.606	EPSD	TCGA;ICGC;COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	Q9C0C2	TNKS1BP1	P24941	CDK2	S1503	P1509S	1509	Missense	distal	6	no	11.873	11.874	EPSD	TCGA;ICGC;COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	Q9C0C2	TNKS1BP1	P24941	CDK2	S1516	E1519K	1519	Missense	distal	3	no	7.637	9.722	EPSD	TCGA;ICGC;COSMIC	8.148	Gain
CMGC_CDK_CDK2_CDK2_ST	Q9C0C2	TNKS1BP1	P24941	CDK2	S1552	A1550T	1550	Missense	proximal	-2	no	16.798	16.749	EPSD	TCGA;ICGC;COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	Q9C0C2	TNKS1BP1	P24941	CDK2	S1552	S1552F	1552	Missense	central	0	yes	16.798	0.000	EPSD	TCGA;ICGC;COSMIC	8.148	Loss
CMGC_CDK_CDK2_CDK2_ST	Q9C0C2	TNKS1BP1	P24941	CDK2	S1602	S1597L	1597	Missense	distal	-5	no	9.221	9.277	EPSD	TCGA;ICGC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	Q9C0C2	TNKS1BP1	P24941	CDK2	S1652	P1649S	1649	Missense	distal	-3	no	12.454	12.549	EPSD	TCGA;ICGC;COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	Q9C0C2	TNKS1BP1	P24941	CDK2	S1715	N1717K	1717	Missense	proximal	2	no	12.430	12.359	EPSD	TCGA;ICGC;COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	Q9C0C2	TNKS1BP1	P24941	CDK2	S1715	A1721S	1721	Missense	distal	6	no	12.430	12.436	EPSD	TCGA;ICGC;COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	Q9C0C2	TNKS1BP1	P24941	CDK2	S1715	S1714L	1714	Missense	proximal	-1	no	12.430	12.722	EPSD	TCGA;ICGC;COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	Q14247	CTTN	P24941	CDK2	S113	Q114P	114	Missense	proximal	1	no	4.332	12.244	EPSD	TCGA;ICGC;COSMIC	8.148	Gain
CMGC_CDK_CDK2_CDK2_ST	Q14247	CTTN	P24941	CDK2	S156	S155F	155	Missense	proximal	-1	no	7.003	8.259	EPSD	TCGA;ICGC;COSMIC	8.148	Gain
CMGC_CDK_CDK2_CDK2_ST	P31749	AKT1	P24941	CDK2	T92	R96W	96	Missense	distal	4	no	13.919	13.559	EPSD	TCGA;ICGC;COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	P31749	AKT1	P24941	CDK2	T92	P93S	93	Missense	proximal	1	no	13.919	2.653	EPSD	TCGA;ICGC;COSMIC	8.148	Loss
CMGC_CDK_CDK2_CDK2_ST	P31749	AKT1	P24941	CDK2	S124	R121W	121	Missense	distal	-3	no	11.662	11.743	EPSD	TCGA;ICGC;COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	P31749	AKT1	P24941	CDK2	S124	A131T	131	Missense	distal	7	no	11.662	10.973	EPSD	TCGA;ICGC;COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	P31749	AKT1	P24941	CDK2	S129	E132K	132	Missense	distal	3	no	7.117	9.203	EPSD	TCGA;COSMIC	8.148	Gain
CMGC_CDK_CDK2_CDK2_ST	P31749	AKT1	P24941	CDK2	S137	E132K	132	Missense	distal	-5	no	8.832	8.798	EPSD	TCGA;COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	P31749	AKT1	P24941	CDK2	S137	E133D	133	Missense	distal	-4	no	8.832	9.129	EPSD	TCGA;ICGC;COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	P31749	AKT1	P24941	CDK2	S137	A131T	131	Missense	distal	-6	no	8.832	8.833	EPSD	TCGA;ICGC;COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	P31749	AKT1	P24941	CDK2	T312	G311D	311	Missense	proximal	-1	no	15.064	14.771	EPSD	TCGA;ICGC;COSMIC;GDSC;CCLE	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	P31749	AKT1	P24941	CDK2	S422	Y417C	417	Missense	distal	-5	no	15.215	15.271	EPSD	TCGA;ICGC;COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	P31749	AKT1	P24941	CDK2	S422	P423T	423	Missense	proximal	1	no	15.215	5.258	EPSD	TCGA;ICGC	8.148	Loss
CMGC_CDK_CDK2_CDK2_ST	P31749	AKT1	P24941	CDK2	S422	E418K	418	Missense	distal	-4	no	15.215	14.904	EPSD	TCGA;ICGC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	P31749	AKT1	P24941	CDK2	T450	I447V	447	Missense	distal	-3	no	8.766	8.889	EPSD	TCGA;ICGC;COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	P82970	HMGN5	P24941	CDK2	S41	S42L	42	Missense	proximal	1	no	6.941	8.386	EPSD	TCGA;ICGC;COSMIC	8.148	Gain
CMGC_CDK_CDK2_CDK2_ST	Q9H8Y8	GORASP2	P24941	CDK2	S26	V22A	22	Missense	distal	-4	no	15.767	15.756	EPSD	TCGA;ICGC;COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	Q9H8Y8	GORASP2	P24941	CDK2	S26	G28E	28	Missense	proximal	2	no	15.767	15.746	EPSD	TCGA;ICGC;COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	Q9H8Y8	GORASP2	P24941	CDK2	S26	S26F	26	Missense	central	0	yes	15.767	0.000	EPSD	TCGA;ICGC;COSMIC	8.148	Loss
CMGC_CDK_CDK2_CDK2_ST	Q9H8Y8	GORASP2	P24941	CDK2	S245	N240I	240	Missense	distal	-5	no	13.398	13.418	EPSD	TCGA;ICGC;COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	Q9H8Y8	GORASP2	P24941	CDK2	T264	S260Y	260	Missense	distal	-4	no	10.515	10.626	EPSD	TCGA;ICGC;COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	P38919	EIF4A3	P24941	CDK2	T163	M170I	170	Missense	distal	7	no	18.812	18.324	PhosphoSitePlus	TCGA;ICGC;COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	P38919	EIF4A3	P24941	CDK2	T163	H158L	158	Missense	distal	-5	no	18.812	18.777	PhosphoSitePlus	TCGA;ICGC;COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	P38919	EIF4A3	P24941	CDK2	T163	R166H	166	Missense	distal	3	no	18.812	18.116	PhosphoSitePlus	TCGA;ICGC;COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	P38919	EIF4A3	P24941	CDK2	T163	H158Y	158	Missense	distal	-5	no	18.812	18.789	PhosphoSitePlus	TCGA;ICGC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	Q9Y253	POLH	P24941	CDK2	S396	D398Y	398	Missense	proximal	2	no	8.442	8.503	EPSD	TCGA;ICGC;COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	Q9Y253	POLH	P24941	CDK2	S396	S396I	396	Missense	central	0	yes	8.442	0.000	EPSD	TCGA;ICGC;COSMIC	8.148	Loss
CMGC_CDK_CDK2_CDK2_ST	Q9Y253	POLH	P24941	CDK2	S416	S409Y	409	Missense	distal	-7	no	14.314	14.620	EPSD	TCGA;ICGC;COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	Q9Y253	POLH	P24941	CDK2	S416	L419V	419	Missense	distal	3	no	14.314	15.306	EPSD	TCGA;ICGC;COSMIC;CCLE	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	Q9Y253	POLH	P24941	CDK2	S512	M509I	509	Missense	distal	-3	no	16.722	16.374	EPSD	TCGA;ICGC;COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	Q9Y253	POLH	P24941	CDK2	S512	S514P	514	Missense	proximal	2	no	16.722	16.656	EPSD	TCGA;ICGC;COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	Q9Y253	POLH	P24941	CDK2	S551	S550Y	550	Missense	proximal	-1	no	12.897	13.807	EPSD	TCGA;ICGC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	Q9Y253	POLH	P24941	CDK2	S551	P556S	556	Missense	distal	5	no	12.897	12.796	EPSD	TCGA;ICGC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	Q9Y253	POLH	P24941	CDK2	S687	R683I	683	Missense	distal	-4	no	13.920	14.012	PhosphoSitePlus	TCGA;ICGC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	P25054	APC	P24941	CDK2	S111	G108A	108	Missense	distal	-3	no	16.473	16.311	EPSD	TCGA;ICGC;COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	P25054	APC	P24941	CDK2	S111	E109A	109	Missense	proximal	-2	no	16.473	17.604	EPSD	TCGA;ICGC;COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	P25054	APC	P24941	CDK2	S306	S299C	299	Missense	distal	-7	no	8.301	8.752	EPSD	TCGA;ICGC;COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	P25054	APC	P24941	CDK2	S306	R302Q	302	Missense	distal	-4	no	8.301	8.326	EPSD	TCGA;ICGC;COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	P25054	APC	P24941	CDK2	S306	E313K	313	Missense	distal	7	no	8.301	7.971	EPSD	TCGA;ICGC;COSMIC	8.148	Loss
CMGC_CDK_CDK2_CDK2_ST	P25054	APC	P24941	CDK2	T324	D328Y	328	Missense	distal	4	no	10.214	10.478	EPSD	TCGA;ICGC;COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	P25054	APC	P24941	CDK2	T324	S331P	331	Missense	distal	7	no	10.214	10.366	EPSD	TCGA;ICGC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	P25054	APC	P24941	CDK2	S744	P745H	745	Missense	proximal	1	no	16.598	9.839	EPSD	TCGA;ICGC;COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	P25054	APC	P24941	CDK2	S744	N741S	741	Missense	distal	-3	no	16.598	16.672	EPSD	TCGA;ICGC;COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	P25054	APC	P24941	CDK2	S780	D777G	777	Missense	distal	-3	no	12.949	12.988	EPSD	TCGA;ICGC;COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	P25054	APC	P24941	CDK2	S780	R786H	786	Missense	distal	6	no	12.949	12.961	EPSD	TCGA;ICGC;COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	P25054	APC	P24941	CDK2	S780	N778S	778	Missense	proximal	-2	no	12.949	13.641	EPSD	TCGA;ICGC;COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	P25054	APC	P24941	CDK2	T1023	L1029I	1029	Missense	distal	6	no	11.779	11.778	EPSD	TCGA;ICGC;COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	P25054	APC	P24941	CDK2	T1023	Y1027H	1027	Missense	distal	4	no	11.779	11.342	EPSD	TCGA;ICGC;COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	P25054	APC	P24941	CDK2	S1042	L1036W	1036	Missense	distal	-6	no	14.087	14.095	EPSD	TCGA;ICGC;COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	P25054	APC	P24941	CDK2	S1042	L1036F	1036	Missense	distal	-6	no	14.087	14.091	EPSD	TCGA;ICGC;COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	P25054	APC	P24941	CDK2	T1082	D1083H	1083	Missense	proximal	1	no	7.885	9.370	EPSD	TCGA;ICGC;COSMIC	8.148	Gain
CMGC_CDK_CDK2_CDK2_ST	P25054	APC	P24941	CDK2	S1100	V1099L	1099	Missense	proximal	-1	no	16.142	16.006	EPSD	TCGA;ICGC;COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	P25054	APC	P24941	CDK2	S1100	R1105Q	1105	Missense	distal	5	no	16.142	15.995	EPSD	TCGA;ICGC;COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	P25054	APC	P24941	CDK2	T1220	T1218M	1218	Missense	proximal	-2	no	11.148	9.097	EPSD	TCGA;ICGC;COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	P25054	APC	P24941	CDK2	T1220	S1215I	1215	Missense	distal	-5	no	11.148	11.232	EPSD	TCGA;ICGC;COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	P25054	APC	P24941	CDK2	T1220	S1219F	1219	Missense	proximal	-1	no	11.148	12.405	EPSD	TCGA;ICGC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	P25054	APC	P24941	CDK2	T1267	E1265Q	1265	Missense	proximal	-2	no	7.722	8.271	EPSD	TCGA;ICGC;COSMIC	8.148	Gain
CMGC_CDK_CDK2_CDK2_ST	P25054	APC	P24941	CDK2	S1356	S1360C	1360	Missense	distal	4	no	8.528	7.767	EPSD	TCGA;ICGC;COSMIC	8.148	Loss
CMGC_CDK_CDK2_CDK2_ST	P25054	APC	P24941	CDK2	S1356	A1358V	1358	Missense	proximal	2	no	8.528	8.626	EPSD	TCGA;ICGC;COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	P25054	APC	P24941	CDK2	S1356	P1361S	1361	Missense	distal	5	no	8.528	8.427	EPSD	TCGA;ICGC;COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	P25054	APC	P24941	CDK2	S1360	S1360C	1360	Missense	central	0	yes	16.350	0.000	PhosphoSitePlus	TCGA;ICGC;COSMIC	8.148	Loss
CMGC_CDK_CDK2_CDK2_ST	P25054	APC	P24941	CDK2	S1360	Q1367E	1367	Missense	distal	7	no	16.350	16.549	PhosphoSitePlus	TCGA;ICGC;COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	P25054	APC	P24941	CDK2	S1360	A1358V	1358	Missense	proximal	-2	no	16.350	15.684	PhosphoSitePlus	TCGA;ICGC;COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	P25054	APC	P24941	CDK2	S1360	P1361S	1361	Missense	proximal	1	no	16.350	5.084	PhosphoSitePlus	TCGA;ICGC;COSMIC	8.148	Loss
CMGC_CDK_CDK2_CDK2_ST	P25054	APC	P24941	CDK2	T1368	Q1367E	1367	Missense	proximal	-1	no	14.571	15.663	EPSD	TCGA;ICGC;COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	P25054	APC	P24941	CDK2	T1368	P1361S	1361	Missense	distal	-7	no	14.571	14.391	EPSD	TCGA;ICGC;COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	P25054	APC	P24941	CDK2	S1371	Q1367E	1367	Missense	distal	-4	no	11.727	12.176	EPSD	TCGA;ICGC;COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	P25054	APC	P24941	CDK2	T1380	R1386K	1386	Missense	distal	6	no	13.550	13.575	EPSD	TCGA;ICGC;COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	P25054	APC	P24941	CDK2	T1380	T1380P	1380	Missense	central	0	yes	13.550	0.000	EPSD	TCGA;ICGC;COSMIC	8.148	Loss
CMGC_CDK_CDK2_CDK2_ST	P25054	APC	P24941	CDK2	T1380	P1381S	1381	Missense	proximal	1	no	13.550	2.284	EPSD	TCGA;ICGC;COSMIC	8.148	Loss
CMGC_CDK_CDK2_CDK2_ST	P25054	APC	P24941	CDK2	S1426	D1422N	1422	Missense	distal	-4	no	13.446	13.058	EPSD	TCGA;ICGC;COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	P25054	APC	P24941	CDK2	S1426	S1421N	1421	Missense	distal	-5	no	13.446	13.509	EPSD	TCGA;ICGC;COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	P25054	APC	P24941	CDK2	T1438	R1435T	1435	Missense	distal	-3	no	11.310	11.082	EPSD	TCGA	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	P25054	APC	P24941	CDK2	T1438	S1434G	1434	Missense	distal	-4	no	11.310	10.637	EPSD	TCGA;ICGC;COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	P25054	APC	P24941	CDK2	T1438	P1442H	1442	Missense	distal	4	no	11.310	11.072	EPSD	TCGA;ICGC;COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	P25054	APC	P24941	CDK2	T1438	S1434I	1434	Missense	distal	-4	no	11.310	10.804	EPSD	TCGA;ICGC;COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	P25054	APC	P24941	CDK2	S1465	E1461K	1461	Missense	distal	-4	no	9.874	9.562	EPSD	TCGA;ICGC;COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	P25054	APC	P24941	CDK2	S1539	E1540G	1540	Missense	proximal	1	no	7.682	9.536	EPSD	TCGA;ICGC;COSMIC	8.148	Gain
CMGC_CDK_CDK2_CDK2_ST	P25054	APC	P24941	CDK2	T1633	R1640W	1640	Missense	distal	7	no	13.131	13.530	EPSD	TCGA;ICGC;COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	P25054	APC	P24941	CDK2	T1633	P1634L	1634	Missense	proximal	1	no	13.131	3.310	EPSD	TCGA;ICGC;COSMIC	8.148	Loss
CMGC_CDK_CDK2_CDK2_ST	P25054	APC	P24941	CDK2	T1647	R1640W	1640	Missense	distal	-7	no	12.866	13.036	EPSD	TCGA;ICGC;COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	P25054	APC	P24941	CDK2	S1664	D1659V	1659	Missense	distal	-5	no	13.896	13.870	EPSD	TCGA;ICGC;COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	P25054	APC	P24941	CDK2	S1774	I1779M	1779	Missense	distal	5	no	16.256	16.471	EPSD	TCGA;ICGC;COSMIC;GDSC;CCLE	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	P25054	APC	P24941	CDK2	S1842	T1847M	1847	Missense	distal	5	no	13.113	13.446	EPSD	TCGA	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	P25054	APC	P24941	CDK2	S1842	Y1846C	1846	Missense	distal	4	no	13.113	12.166	EPSD	TCGA;ICGC;COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	P25054	APC	P24941	CDK2	T1847	T1847M	1847	Missense	central	0	yes	14.877	0.000	EPSD	TCGA	8.148	Loss
CMGC_CDK_CDK2_CDK2_ST	P25054	APC	P24941	CDK2	T1847	Y1846C	1846	Missense	proximal	-1	no	14.877	14.311	EPSD	TCGA;ICGC;COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	P25054	APC	P24941	CDK2	T1852	T1847M	1847	Missense	distal	-5	no	9.471	9.579	EPSD	TCGA	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	P25054	APC	P24941	CDK2	T1852	Y1846C	1846	Missense	distal	-6	no	9.471	9.476	EPSD	TCGA;ICGC;COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	P25054	APC	P24941	CDK2	S1995	E1998K	1998	Missense	distal	3	no	7.515	9.600	EPSD	TCGA;ICGC;COSMIC	8.148	Gain
CMGC_CDK_CDK2_CDK2_ST	P25054	APC	P24941	CDK2	T2017	T2017A	2017	Missense	central	0	yes	8.849	0.000	EPSD	TCGA;ICGC;COSMIC	8.148	Loss
CMGC_CDK_CDK2_CDK2_ST	P25054	APC	P24941	CDK2	T2017	T2017I	2017	Missense	central	0	yes	8.849	0.000	EPSD	TCGA;ICGC	8.148	Loss
CMGC_CDK_CDK2_CDK2_ST	P25054	APC	P24941	CDK2	T2017	F2021L	2021	Missense	distal	4	no	8.849	9.144	EPSD	TCGA;ICGC;COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	P25054	APC	P24941	CDK2	T2151	Q2154E	2154	Missense	distal	3	no	12.566	13.213	EPSD	TCGA;ICGC;COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	P25054	APC	P24941	CDK2	S2183	E2184Q	2184	Missense	proximal	1	no	8.354	9.608	EPSD	TCGA;ICGC;COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	P25054	APC	P24941	CDK2	S2183	K2180R	2180	Missense	distal	-3	no	8.354	8.584	EPSD	TCGA;ICGC;COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	P25054	APC	P24941	CDK2	S2183	K2189R	2189	Missense	distal	6	no	8.354	8.330	EPSD	TCGA;ICGC;COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	P25054	APC	P24941	CDK2	S2244	T2243A	2243	Missense	proximal	-1	no	13.417	13.410	EPSD	TCGA;ICGC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	P25054	APC	P24941	CDK2	S2244	G2250V	2250	Missense	distal	6	no	13.417	13.427	EPSD	TCGA;ICGC;COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	P25054	APC	P24941	CDK2	S2244	S2242N	2242	Missense	proximal	-2	no	13.417	12.725	EPSD	TCGA;ICGC;COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	P25054	APC	P24941	CDK2	S2244	S2242I	2242	Missense	proximal	-2	no	13.417	13.914	EPSD	TCGA;ICGC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	P25054	APC	P24941	CDK2	S2244	P2245H	2245	Missense	proximal	1	no	13.417	6.659	EPSD	TCGA;ICGC	8.148	Loss
CMGC_CDK_CDK2_CDK2_ST	P25054	APC	P24941	CDK2	T2255	G2250V	2250	Missense	distal	-5	no	11.583	11.534	EPSD	TCGA;ICGC;COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	P25054	APC	P24941	CDK2	T2255	P2256L	2256	Missense	proximal	1	no	11.583	1.762	EPSD	TCGA;ICGC;COSMIC	8.148	Loss
CMGC_CDK_CDK2_CDK2_ST	P25054	APC	P24941	CDK2	T2255	L2253F	2253	Missense	proximal	-2	no	11.583	10.694	EPSD	TCGA;ICGC;COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	P25054	APC	P24941	CDK2	T2255	L2253I	2253	Missense	proximal	-2	no	11.583	11.653	EPSD	TCGA;ICGC;COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	P25054	APC	P24941	CDK2	S2260	P2256L	2256	Missense	distal	-4	no	13.997	13.938	EPSD	TCGA;ICGC;COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	P25054	APC	P24941	CDK2	S2260	L2253F	2253	Missense	distal	-7	no	13.997	14.363	EPSD	TCGA;ICGC;COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	P25054	APC	P24941	CDK2	S2260	L2253I	2253	Missense	distal	-7	no	13.997	14.186	EPSD	TCGA;ICGC;COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	P25054	APC	P24941	CDK2	S2270	S2277A	2277	Missense	distal	7	no	11.659	12.196	EPSD	TCGA;ICGC;COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	P25054	APC	P24941	CDK2	T2308	S2307L	2307	Missense	proximal	-1	no	15.857	16.149	EPSD	TCGA;ICGC;COSMIC;CCLE	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	P25054	APC	P24941	CDK2	T2308	A2313S	2313	Missense	distal	5	no	15.857	15.746	EPSD	TCGA;ICGC;COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	P25054	APC	P24941	CDK2	S2323	P2324T	2324	Missense	proximal	1	no	14.191	4.233	EPSD	TCGA;ICGC	8.148	Loss
CMGC_CDK_CDK2_CDK2_ST	P25054	APC	P24941	CDK2	S2330	P2324T	2324	Missense	distal	-6	no	11.612	11.611	EPSD	TCGA;ICGC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	P25054	APC	P24941	CDK2	S2350	P2346S	2346	Missense	distal	-4	no	13.220	13.574	EPSD	TCGA;ICGC;COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	P25054	APC	P24941	CDK2	S2368	Q2372H	2372	Missense	distal	4	no	16.725	16.426	EPSD	TCGA;ICGC;COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	P25054	APC	P24941	CDK2	S2449	F2443L	2443	Missense	distal	-6	no	14.181	14.177	EPSD	TCGA;ICGC;COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	P25054	APC	P24941	CDK2	S2449	F2443Y	2443	Missense	distal	-6	no	14.181	14.177	EPSD	TCGA;ICGC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	P25054	APC	P24941	CDK2	S2466	A2472D	2472	Missense	distal	6	no	11.045	11.034	EPSD	TCGA;ICGC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	P25054	APC	P24941	CDK2	S2466	S2464Y	2464	Missense	proximal	-2	no	11.045	11.132	EPSD	TCGA;ICGC;COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	P25054	APC	P24941	CDK2	S2473	A2472D	2472	Missense	proximal	-1	no	14.466	15.492	EPSD	TCGA;ICGC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	P25054	APC	P24941	CDK2	S2512	E2516Q	2516	Missense	distal	4	no	12.667	12.712	EPSD	TCGA;ICGC;COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	P25054	APC	P24941	CDK2	S2512	P2509S	2509	Missense	distal	-3	no	12.667	12.763	EPSD	TCGA;ICGC;COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	P25054	APC	P24941	CDK2	S2512	I2515V	2515	Missense	distal	3	no	12.667	13.944	EPSD	TCGA;ICGC;COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	P25054	APC	P24941	CDK2	S2512	S2512R	2512	Missense	central	0	yes	12.667	0.000	EPSD	TCGA;ICGC;COSMIC	8.148	Loss
CMGC_CDK_CDK2_CDK2_ST	P25054	APC	P24941	CDK2	S2512	L2511I	2511	Missense	proximal	-1	no	12.667	12.830	EPSD	TCGA;ICGC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	P25054	APC	P24941	CDK2	S2531	R2525C	2525	Missense	distal	-6	no	9.125	9.128	EPSD	TCGA;ICGC;COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	P25054	APC	P24941	CDK2	S2531	H2532Y	2532	Missense	proximal	1	no	9.125	0.384	EPSD	TCGA;ICGC;COSMIC	8.148	Loss
CMGC_CDK_CDK2_CDK2_ST	P25054	APC	P24941	CDK2	S2535	I2541V	2541	Missense	distal	6	no	14.642	14.640	EPSD	TCGA;ICGC;COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	P25054	APC	P24941	CDK2	S2535	P2540S	2540	Missense	distal	5	no	14.642	14.541	EPSD	TCGA;ICGC;COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	P25054	APC	P24941	CDK2	S2535	H2532Y	2532	Missense	distal	-3	no	14.642	14.610	EPSD	TCGA;ICGC;COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	P25054	APC	P24941	CDK2	S2621	N2624D	2624	Missense	distal	3	no	11.510	10.259	EPSD	TCGA;ICGC;COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	P25054	APC	P24941	CDK2	S2674	S2671Y	2671	Missense	distal	-3	no	10.985	11.005	EPSD	TCGA;ICGC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	P25054	APC	P24941	CDK2	S2674	S2674Y	2674	Missense	central	0	yes	10.985	0.000	EPSD	TCGA;ICGC;COSMIC	8.148	Loss
CMGC_CDK_CDK2_CDK2_ST	P25054	APC	P24941	CDK2	T2679	S2674Y	2674	Missense	distal	-5	no	14.248	14.316	EPSD	TCGA;ICGC;COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	P25054	APC	P24941	CDK2	T2760	R2759H	2759	Missense	proximal	-1	no	13.102	12.650	EPSD	TCGA;ICGC;COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	P25054	APC	P24941	CDK2	T2760	S2755Y	2755	Missense	distal	-5	no	13.102	13.170	EPSD	TCGA;ICGC;COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	P25054	APC	P24941	CDK2	S2772	G2775V	2775	Missense	distal	3	no	10.099	10.808	EPSD	TCGA;ICGC;COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	P25054	APC	P24941	CDK2	S2772	A2779V	2779	Missense	distal	7	no	10.099	9.972	EPSD	TCGA;ICGC;COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	P25054	APC	P24941	CDK2	T2782	R2780T	2780	Missense	proximal	-2	no	11.635	12.838	EPSD	TCGA;ICGC;COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	P25054	APC	P24941	CDK2	T2782	F2784C	2784	Missense	proximal	2	no	11.635	11.530	EPSD	TCGA;ICGC;COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	P25054	APC	P24941	CDK2	T2782	P2783L	2783	Missense	proximal	1	no	11.635	1.814	EPSD	TCGA;ICGC;COSMIC	8.148	Loss
CMGC_CDK_CDK2_CDK2_ST	P25054	APC	P24941	CDK2	T2782	G2775V	2775	Missense	distal	-7	no	11.635	11.331	EPSD	TCGA;ICGC;COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	P25054	APC	P24941	CDK2	T2782	A2779V	2779	Missense	distal	-3	no	11.635	11.837	EPSD	TCGA;ICGC;COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	P25054	APC	P24941	CDK2	S2789	F2784C	2784	Missense	distal	-5	no	17.055	17.063	EPSD	TCGA;ICGC;COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	P25054	APC	P24941	CDK2	S2789	S2794T	2794	Missense	distal	5	no	17.055	17.130	EPSD	TCGA;ICGC;COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	P25054	APC	P24941	CDK2	S2803	Q2804P	2804	Missense	proximal	1	no	4.166	12.078	EPSD	TCGA	8.148	Gain
CMGC_CDK_CDK2_CDK2_ST	P25054	APC	P24941	CDK2	T2807	R2801W	2801	Missense	distal	-6	no	13.457	13.463	EPSD	TCGA;ICGC;COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	P25054	APC	P24941	CDK2	T2807	Q2804P	2804	Missense	distal	-3	no	13.457	13.399	EPSD	TCGA	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	P25054	APC	P24941	CDK2	S2830	T2823R	2823	Missense	distal	-7	no	15.826	16.172	EPSD	TCGA;ICGC;COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	Q99626	CDX2	P24941	CDK2	S60	P61S	61	Missense	proximal	1	no	15.238	3.972	EPSD	TCGA;ICGC;COSMIC	8.148	Loss
CMGC_CDK_CDK2_CDK2_ST	Q99626	CDX2	P24941	CDK2	S283	L288V	288	Missense	distal	5	no	15.969	15.896	PhosphoSitePlus	TCGA;ICGC;COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	Q13118	KLF10	P24941	CDK2	T66	V60L	60	Missense	distal	-6	no	13.960	13.958	EPSD	TCGA;COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	Q13118	KLF10	P24941	CDK2	T66	P67L	67	Missense	proximal	1	no	13.960	4.139	EPSD	TCGA;COSMIC	8.148	Loss
CMGC_CDK_CDK2_CDK2_ST	Q13118	KLF10	P24941	CDK2	T66	P64H	64	Missense	proximal	-2	no	13.960	12.950	EPSD	TCGA;COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	Q13118	KLF10	P24941	CDK2	T66	Y59H	59	Missense	distal	-7	no	13.960	13.957	EPSD	TCGA	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	Q13118	KLF10	P24941	CDK2	T93	S97N	97	Missense	distal	4	no	11.657	11.623	EPSD	TCGA	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	Q13118	KLF10	P24941	CDK2	T93	P94A	94	Missense	proximal	1	no	11.657	-2.746	EPSD	TCGA;COSMIC	8.148	Loss
CMGC_CDK_CDK2_CDK2_ST	Q13118	KLF10	P24941	CDK2	S97	S97N	97	Missense	central	0	yes	13.807	0.000	EPSD	TCGA	8.148	Loss
CMGC_CDK_CDK2_CDK2_ST	Q13118	KLF10	P24941	CDK2	S97	P94A	94	Missense	distal	-3	no	13.807	13.748	EPSD	TCGA;COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	Q13118	KLF10	P24941	CDK2	S140	E138K	138	Missense	proximal	-2	no	13.926	14.527	EPSD	TCGA;COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	Q13118	KLF10	P24941	CDK2	S249	V248M	248	Missense	proximal	-1	no	16.829	17.922	EPSD	TCGA;COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	Q13118	KLF10	P24941	CDK2	S335	N337S	337	Missense	proximal	2	no	12.123	12.260	EPSD	TCGA;COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	Q13118	KLF10	P24941	CDK2	S335	G338D	338	Missense	distal	3	no	12.123	10.410	EPSD	TCGA;COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	Q13118	KLF10	P24941	CDK2	S335	S329L	329	Missense	distal	-6	no	12.123	12.124	EPSD	TCGA;COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	Q13118	KLF10	P24941	CDK2	S335	S335N	335	Missense	central	0	yes	12.123	0.000	EPSD	TCGA;COSMIC	8.148	Loss
CMGC_CDK_CDK2_CDK2_ST	Q13118	KLF10	P24941	CDK2	S342	N337S	337	Missense	distal	-5	no	11.751	11.688	EPSD	TCGA;COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	Q13118	KLF10	P24941	CDK2	S342	P348L	348	Missense	distal	6	no	11.751	11.753	EPSD	TCGA;ICGC;COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	Q13118	KLF10	P24941	CDK2	S342	G338D	338	Missense	distal	-4	no	11.751	12.596	EPSD	TCGA;COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	Q13118	KLF10	P24941	CDK2	S342	S335N	335	Missense	distal	-7	no	11.751	11.850	EPSD	TCGA;COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	Q13118	KLF10	P24941	CDK2	S351	P348L	348	Missense	distal	-3	no	11.257	11.186	EPSD	TCGA;ICGC;COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	Q13118	KLF10	P24941	CDK2	S351	F350C	350	Missense	proximal	-1	no	11.257	10.344	EPSD	TCGA	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	Q13118	KLF10	P24941	CDK2	S351	P352S	352	Missense	proximal	1	no	11.257	-0.009	EPSD	TCGA;COSMIC	8.148	Loss
CMGC_CDK_CDK2_CDK2_ST	Q13118	KLF10	P24941	CDK2	S351	P352L	352	Missense	proximal	1	no	11.257	1.436	EPSD	TCGA;COSMIC	8.148	Loss
CMGC_CDK_CDK2_CDK2_ST	Q13118	KLF10	P24941	CDK2	S351	V357I	357	Missense	distal	6	no	11.257	11.259	EPSD	TCGA;COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	Q13118	KLF10	P24941	CDK2	T358	P359L	359	Missense	proximal	1	no	10.913	1.092	EPSD	TCGA;COSMIC	8.148	Loss
CMGC_CDK_CDK2_CDK2_ST	Q13118	KLF10	P24941	CDK2	T358	P352S	352	Missense	distal	-6	no	10.913	10.912	EPSD	TCGA;COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	Q13118	KLF10	P24941	CDK2	T358	V357I	357	Missense	proximal	-1	no	10.913	10.939	EPSD	TCGA;COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	Q13118	KLF10	P24941	CDK2	S384	Y380C	380	Missense	distal	-4	no	9.740	8.523	EPSD	TCGA;COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	Q13118	KLF10	P24941	CDK2	T394	T392M	392	Missense	proximal	-2	no	8.999	6.948	EPSD	TCGA;COSMIC	8.148	Loss
CMGC_CDK_CDK2_CDK2_ST	Q13118	KLF10	P24941	CDK2	T424	R418K	418	Missense	distal	-6	no	10.361	10.359	EPSD	TCGA;COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	Q13118	KLF10	P24941	CDK2	T424	A430V	430	Missense	distal	6	no	10.361	10.364	EPSD	TCGA;COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	Q13118	KLF10	P24941	CDK2	T424	T424M	424	Missense	central	0	yes	10.361	0.000	EPSD	TCGA;COSMIC	8.148	Loss
CMGC_CDK_CDK2_CDK2_ST	Q9C0C9	UBE2O	P24941	CDK2	S115	P116T	116	Missense	proximal	1	no	18.115	8.157	EPSD	TCGA;ICGC;COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	Q9C0C9	UBE2O	P24941	CDK2	S322	D319N	319	Missense	distal	-3	no	13.907	13.863	EPSD	TCGA;ICGC;COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	Q9C0C9	UBE2O	P24941	CDK2	S322	V321I	321	Missense	proximal	-1	no	13.907	13.933	EPSD	TCGA;ICGC;COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	Q9C0C9	UBE2O	P24941	CDK2	S401	P402S	402	Missense	proximal	1	no	15.375	4.109	EPSD	TCGA	8.148	Loss
CMGC_CDK_CDK2_CDK2_ST	Q9C0C9	UBE2O	P24941	CDK2	S401	R408L	408	Missense	distal	7	no	15.375	14.915	EPSD	TCGA	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	Q9C0C9	UBE2O	P24941	CDK2	S401	S407C	407	Missense	distal	6	no	15.375	15.360	EPSD	TCGA;ICGC;COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	Q9C0C9	UBE2O	P24941	CDK2	S401	C406Y	406	Missense	distal	5	no	15.375	15.214	EPSD	TCGA;ICGC;COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	Q9C0C9	UBE2O	P24941	CDK2	S431	P432L	432	Missense	proximal	1	no	13.497	3.676	EPSD	TCGA;ICGC;COSMIC	8.148	Loss
CMGC_CDK_CDK2_CDK2_ST	Q9C0C9	UBE2O	P24941	CDK2	T435	P432L	432	Missense	distal	-3	no	13.424	13.353	EPSD	TCGA;ICGC;COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	Q9C0C9	UBE2O	P24941	CDK2	S441	E448K	448	Missense	distal	7	no	14.465	14.134	EPSD	TCGA;ICGC;COSMIC;GDSC;CCLE	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	Q9C0C9	UBE2O	P24941	CDK2	S836	S836L	836	Missense	central	0	yes	13.935	0.000	PhosphoSitePlus	TCGA;ICGC	8.148	Loss
CMGC_CDK_CDK2_CDK2_ST	Q9C0C9	UBE2O	P24941	CDK2	S839	E845D	845	Missense	distal	6	no	13.018	13.006	EPSD	TCGA;ICGC;COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	Q9C0C9	UBE2O	P24941	CDK2	S839	S836L	836	Missense	distal	-3	no	13.018	12.852	EPSD	TCGA;ICGC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	Q9C0C9	UBE2O	P24941	CDK2	T848	E845D	845	Missense	distal	-3	no	9.357	9.247	EPSD	TCGA;ICGC;COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	Q9C0C9	UBE2O	P24941	CDK2	S896	E893K	893	Missense	distal	-3	no	14.068	13.853	EPSD	TCGA;ICGC;COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	Q9C0C9	UBE2O	P24941	CDK2	T906	E905K	905	Missense	proximal	-1	no	13.623	12.738	EPSD	TCGA;ICGC;COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	Q9C0C9	UBE2O	P24941	CDK2	S1168	S1168L	1168	Missense	central	0	yes	14.767	0.000	EPSD	TCGA;ICGC;COSMIC	8.148	Loss
CMGC_CDK_CDK2_CDK2_ST	P23258	TUBG1	P24941	CDK2	T45	E43K	43	Missense	proximal	-2	no	10.767	11.368	EPSD	TCGA;ICGC;COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	P23258	TUBG1	P24941	CDK2	S179	E177K	177	Missense	proximal	-2	no	7.765	8.366	EPSD	TCGA;ICGC;COSMIC	8.148	Gain
CMGC_CDK_CDK2_CDK2_ST	P23258	TUBG1	P24941	CDK2	T263	P262L	262	Missense	proximal	-1	no	14.674	14.495	EPSD	TCGA;ICGC;COSMIC;GDSC;CCLE	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	P23258	TUBG1	P24941	CDK2	T274	S281L	281	Missense	distal	7	no	11.231	11.413	EPSD	TCGA;ICGC;COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	P23258	TUBG1	P24941	CDK2	T274	T278M	278	Missense	distal	4	no	11.231	10.527	EPSD	TCGA;ICGC;COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	P23258	TUBG1	P24941	CDK2	S364	P368T	368	Missense	distal	4	no	11.482	11.765	EPSD	TCGA;ICGC;COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	P23258	TUBG1	P24941	CDK2	S364	P368L	368	Missense	distal	4	no	11.482	11.594	EPSD	TCGA;ICGC;COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	Q9ULW0	TPX2	P24941	CDK2	T59	G53V	53	Missense	distal	-6	no	12.983	12.982	EPSD	TCGA;ICGC;COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	Q9ULW0	TPX2	P24941	CDK2	T59	P60L	60	Missense	proximal	1	no	12.983	3.162	EPSD	TCGA;ICGC;COSMIC	8.148	Loss
CMGC_CDK_CDK2_CDK2_ST	Q9ULW0	TPX2	P24941	CDK2	T72	T72A	72	Missense	central	0	yes	14.194	0.000	PhosphoSitePlus	TCGA;ICGC;COSMIC	8.148	Loss
CMGC_CDK_CDK2_CDK2_ST	Q9ULW0	TPX2	P24941	CDK2	T113	A115T	115	Missense	proximal	2	no	12.783	12.581	EPSD	TCGA;ICGC;COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	Q9ULW0	TPX2	P24941	CDK2	T147	K143N	143	Missense	distal	-4	no	11.943	12.162	EPSD	TCGA;ICGC;COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	Q9ULW0	TPX2	P24941	CDK2	T147	A146P	146	Missense	proximal	-1	no	11.943	12.213	EPSD	TCGA;ICGC;COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	Q9ULW0	TPX2	P24941	CDK2	S186	A184T	184	Missense	proximal	-2	no	16.123	16.074	EPSD	TCGA;ICGC;COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	Q9ULW0	TPX2	P24941	CDK2	S293	R288Q	288	Missense	distal	-5	no	15.428	15.381	EPSD	TCGA;ICGC;COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	Q9ULW0	TPX2	P24941	CDK2	S293	R288L	288	Missense	distal	-5	no	15.428	15.393	EPSD	TCGA;ICGC;COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	Q9ULW0	TPX2	P24941	CDK2	S293	P294H	294	Missense	proximal	1	no	15.428	8.670	EPSD	TCGA;ICGC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	Q9ULW0	TPX2	P24941	CDK2	S293	G300V	300	Missense	distal	7	no	15.428	15.017	EPSD	TCGA;ICGC;COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	Q9ULW0	TPX2	P24941	CDK2	S293	P291L	291	Missense	proximal	-2	no	15.428	15.204	EPSD	TCGA;ICGC;COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	Q9ULW0	TPX2	P24941	CDK2	T338	R341I	341	Missense	distal	3	no	15.150	12.764	EPSD	TCGA;COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	Q9ULW0	TPX2	P24941	CDK2	T338	R345S	345	Missense	distal	7	no	15.150	14.509	EPSD	TCGA	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	Q9ULW0	TPX2	P24941	CDK2	T338	R337Q	337	Missense	proximal	-1	no	15.150	14.272	EPSD	TCGA;ICGC;COSMIC;GDSC;CCLE	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	Q9ULW0	TPX2	P24941	CDK2	T369	P370A	370	Missense	proximal	1	no	11.771	-2.632	EPSD	TCGA;COSMIC	8.148	Loss
CMGC_CDK_CDK2_CDK2_ST	Q9ULW0	TPX2	P24941	CDK2	T369	K362N	362	Missense	distal	-7	no	11.771	11.737	EPSD	TCGA;COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	Q9ULW0	TPX2	P24941	CDK2	S738	R744Q	744	Missense	distal	6	no	17.039	17.061	EPSD	TCGA;ICGC;COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	O14686	KMT2D	P24941	CDK2	T366	R371G	371	Missense	distal	5	no	11.166	11.186	EPSD	TCGA;ICGC;COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	O14686	KMT2D	P24941	CDK2	S373	R371G	371	Missense	proximal	-2	no	16.228	16.722	EPSD	TCGA;ICGC;COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	O14686	KMT2D	P24941	CDK2	S468	R466H	466	Missense	proximal	-2	no	13.541	13.767	EPSD	TCGA;ICGC;COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	O14686	KMT2D	P24941	CDK2	S468	A464V	464	Missense	distal	-4	no	13.541	13.552	EPSD	TCGA;ICGC;COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	O14686	KMT2D	P24941	CDK2	S468	R466C	466	Missense	proximal	-2	no	13.541	13.715	EPSD	TCGA;ICGC;COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	O14686	KMT2D	P24941	CDK2	S477	A482T	482	Missense	distal	5	no	11.570	11.534	EPSD	TCGA;ICGC;COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	O14686	KMT2D	P24941	CDK2	S579	M581V	581	Missense	proximal	2	no	14.706	14.618	EPSD	TCGA;ICGC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	O14686	KMT2D	P24941	CDK2	S582	M581V	581	Missense	proximal	-1	no	13.351	12.258	EPSD	TCGA;ICGC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	O14686	KMT2D	P24941	CDK2	S588	M581V	581	Missense	distal	-7	no	13.239	12.758	EPSD	TCGA;ICGC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	O14686	KMT2D	P24941	CDK2	S591	R598H	598	Missense	distal	7	no	14.123	13.765	EPSD	TCGA;ICGC;COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	O14686	KMT2D	P24941	CDK2	S591	R598C	598	Missense	distal	7	no	14.123	14.274	EPSD	TCGA;ICGC;COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	O14686	KMT2D	P24941	CDK2	S606	S606F	606	Missense	central	0	yes	13.374	0.000	EPSD	TCGA;ICGC;COSMIC	8.148	Loss
CMGC_CDK_CDK2_CDK2_ST	O14686	KMT2D	P24941	CDK2	S606	P602S	602	Missense	distal	-4	no	13.374	13.728	EPSD	TCGA;ICGC;COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	O14686	KMT2D	P24941	CDK2	S609	P616L	616	Missense	distal	7	no	11.823	11.854	EPSD	TCGA;ICGC;COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	O14686	KMT2D	P24941	CDK2	S609	S606F	606	Missense	distal	-3	no	11.823	11.915	EPSD	TCGA;ICGC;COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	O14686	KMT2D	P24941	CDK2	S609	P602S	602	Missense	distal	-7	no	11.823	11.643	EPSD	TCGA;ICGC;COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	O14686	KMT2D	P24941	CDK2	S615	P616L	616	Missense	proximal	1	no	13.518	3.697	EPSD	TCGA;ICGC;COSMIC	8.148	Loss
CMGC_CDK_CDK2_CDK2_ST	O14686	KMT2D	P24941	CDK2	S618	P616L	616	Missense	proximal	-2	no	13.691	13.466	EPSD	TCGA;ICGC;COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	O14686	KMT2D	P24941	CDK2	S654	R661C	661	Missense	distal	7	no	11.205	11.356	EPSD	TCGA;ICGC;COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	O14686	KMT2D	P24941	CDK2	S663	E667D	667	Missense	distal	4	no	11.009	10.927	EPSD	TCGA;ICGC;COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	O14686	KMT2D	P24941	CDK2	S663	E667Q	667	Missense	distal	4	no	11.009	11.053	EPSD	TCGA;ICGC;COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	O14686	KMT2D	P24941	CDK2	S663	R661C	661	Missense	proximal	-2	no	11.009	11.183	EPSD	TCGA;ICGC;COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	O14686	KMT2D	P24941	CDK2	S663	P665L	665	Missense	proximal	2	no	11.009	10.902	EPSD	TCGA;ICGC;COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	O14686	KMT2D	P24941	CDK2	S669	E667D	667	Missense	proximal	-2	no	12.383	13.363	EPSD	TCGA;ICGC;COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	O14686	KMT2D	P24941	CDK2	S669	E667Q	667	Missense	proximal	-2	no	12.383	12.931	EPSD	TCGA;ICGC;COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	O14686	KMT2D	P24941	CDK2	S669	P665L	665	Missense	distal	-4	no	12.383	12.324	EPSD	TCGA;ICGC;COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	O14686	KMT2D	P24941	CDK2	S672	E667D	667	Missense	distal	-5	no	12.318	12.338	EPSD	TCGA;ICGC;COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	O14686	KMT2D	P24941	CDK2	S672	E667Q	667	Missense	distal	-5	no	12.318	12.281	EPSD	TCGA;ICGC;COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	O14686	KMT2D	P24941	CDK2	S672	E677A	677	Missense	distal	5	no	12.318	12.249	EPSD	TCGA;ICGC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	O14686	KMT2D	P24941	CDK2	S672	P665L	665	Missense	distal	-7	no	12.318	12.324	EPSD	TCGA;ICGC;COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	O14686	KMT2D	P24941	CDK2	S678	E677A	677	Missense	proximal	-1	no	12.374	11.319	EPSD	TCGA;ICGC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	O14686	KMT2D	P24941	CDK2	S681	E677A	677	Missense	distal	-4	no	12.996	12.707	EPSD	TCGA;ICGC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	O14686	KMT2D	P24941	CDK2	S744	P745S	745	Missense	proximal	1	no	12.383	1.117	EPSD	TCGA;ICGC;COSMIC	8.148	Loss
CMGC_CDK_CDK2_CDK2_ST	O14686	KMT2D	P24941	CDK2	S744	R746W	746	Missense	proximal	2	no	12.383	12.480	EPSD	TCGA;ICGC;COSMIC;GDSC;CCLE	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	O14686	KMT2D	P24941	CDK2	S744	P750L	750	Missense	distal	6	no	12.383	12.385	EPSD	TCGA;ICGC;COSMIC;CCLE	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	O14686	KMT2D	P24941	CDK2	S753	P754A	754	Missense	proximal	1	no	12.827	-1.576	EPSD	TCGA	8.148	Loss
CMGC_CDK_CDK2_CDK2_ST	O14686	KMT2D	P24941	CDK2	S753	R755Q	755	Missense	proximal	2	no	12.827	12.727	EPSD	TCGA;ICGC;COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	O14686	KMT2D	P24941	CDK2	S753	R746W	746	Missense	distal	-7	no	12.827	12.998	EPSD	TCGA;ICGC;COSMIC;GDSC;CCLE	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	O14686	KMT2D	P24941	CDK2	S753	P750L	750	Missense	distal	-3	no	12.827	12.756	EPSD	TCGA;ICGC;COSMIC;CCLE	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	O14686	KMT2D	P24941	CDK2	S762	E766K	766	Missense	distal	4	no	12.215	12.599	EPSD	TCGA;ICGC;COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	O14686	KMT2D	P24941	CDK2	S762	R755Q	755	Missense	distal	-7	no	12.215	11.828	EPSD	TCGA;ICGC;COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	O14686	KMT2D	P24941	CDK2	S952	P953S	953	Missense	proximal	1	no	13.678	2.412	EPSD	TCGA;ICGC;COSMIC	8.148	Loss
CMGC_CDK_CDK2_CDK2_ST	O14686	KMT2D	P24941	CDK2	S952	P953L	953	Missense	proximal	1	no	13.678	3.857	EPSD	TCGA;ICGC;COSMIC	8.148	Loss
CMGC_CDK_CDK2_CDK2_ST	O14686	KMT2D	P24941	CDK2	S1037	S1040F	1040	Missense	distal	3	no	10.916	10.840	EPSD	TCGA;ICGC;COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	O14686	KMT2D	P24941	CDK2	S1037	P1044H	1044	Missense	distal	7	no	10.916	11.047	EPSD	TCGA;ICGC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	O14686	KMT2D	P24941	CDK2	S1043	S1040F	1040	Missense	distal	-3	no	10.603	10.695	EPSD	TCGA;ICGC;COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	O14686	KMT2D	P24941	CDK2	S1043	P1044H	1044	Missense	proximal	1	no	10.603	3.845	EPSD	TCGA;ICGC	8.148	Loss
CMGC_CDK_CDK2_CDK2_ST	O14686	KMT2D	P24941	CDK2	S1180	Q1178H	1178	Missense	proximal	-2	no	16.075	15.632	EPSD	TCGA	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	O14686	KMT2D	P24941	CDK2	S1180	G1179D	1179	Missense	proximal	-1	no	16.075	15.782	EPSD	TCGA;ICGC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	O14686	KMT2D	P24941	CDK2	T1195	I1200M	1200	Missense	distal	5	no	14.225	14.440	EPSD	TCGA;ICGC;COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	O14686	KMT2D	P24941	CDK2	T1195	R1189H	1189	Missense	distal	-6	no	14.225	14.226	EPSD	TCGA;ICGC;COSMIC;GDSC;CCLE	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	O14686	KMT2D	P24941	CDK2	S1249	R1252L	1252	Missense	distal	3	no	16.439	14.337	EPSD	TCGA;ICGC;COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	O14686	KMT2D	P24941	CDK2	S1280	A1275V	1275	Missense	distal	-5	no	8.271	8.277	EPSD	TCGA;ICGC;COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	O14686	KMT2D	P24941	CDK2	S1294	R1292C	1292	Missense	proximal	-2	no	15.567	15.741	EPSD	TCGA;ICGC;COSMIC;GDSC;CCLE	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	O14686	KMT2D	P24941	CDK2	S1294	R1290W	1290	Missense	distal	-4	no	15.567	14.809	EPSD	TCGA;ICGC;COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	O14686	KMT2D	P24941	CDK2	S1298	R1292C	1292	Missense	distal	-6	no	8.882	8.885	EPSD	TCGA;ICGC;COSMIC;GDSC;CCLE	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	O14686	KMT2D	P24941	CDK2	S1606	R1611W	1611	Missense	distal	5	no	16.246	16.412	EPSD	TCGA;ICGC;COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	O14686	KMT2D	P24941	CDK2	S1606	R1612H	1612	Missense	distal	6	no	16.246	16.257	EPSD	TCGA;ICGC;COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	O14686	KMT2D	P24941	CDK2	S1671	P1669S	1669	Missense	proximal	-2	no	15.472	14.820	EPSD	TCGA;ICGC;COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	O14686	KMT2D	P24941	CDK2	S1671	S1671I	1671	Missense	central	0	yes	15.472	0.000	EPSD	TCGA;ICGC;COSMIC	8.148	Loss
CMGC_CDK_CDK2_CDK2_ST	O14686	KMT2D	P24941	CDK2	T1843	D1848N	1848	Missense	distal	5	no	16.149	16.078	EPSD	TCGA;ICGC;COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	O14686	KMT2D	P24941	CDK2	S1854	D1848N	1848	Missense	distal	-6	no	15.691	15.692	EPSD	TCGA;ICGC;COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	O14686	KMT2D	P24941	CDK2	S1854	A1853V	1853	Missense	proximal	-1	no	15.691	15.918	EPSD	TCGA;ICGC;COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	O14686	KMT2D	P24941	CDK2	S1854	P1855L	1855	Missense	proximal	1	no	15.691	5.870	EPSD	TCGA;ICGC;COSMIC	8.148	Loss
CMGC_CDK_CDK2_CDK2_ST	O14686	KMT2D	P24941	CDK2	T1865	S1872I	1872	Missense	distal	7	no	16.932	17.140	EPSD	TCGA;ICGC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	O14686	KMT2D	P24941	CDK2	T1911	S1917G	1917	Missense	distal	6	no	12.443	12.430	EPSD	TCGA;ICGC;COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	O14686	KMT2D	P24941	CDK2	T1911	L1907V	1907	Missense	distal	-4	no	12.443	12.453	EPSD	TCGA;ICGC;COSMIC;GDSC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	O14686	KMT2D	P24941	CDK2	T1919	S1917G	1917	Missense	proximal	-2	no	12.736	12.645	EPSD	TCGA;ICGC;COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	O14686	KMT2D	P24941	CDK2	T1919	P1924L	1924	Missense	distal	5	no	12.736	12.776	EPSD	TCGA;ICGC;COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	O14686	KMT2D	P24941	CDK2	S1939	P1940T	1940	Missense	proximal	1	no	13.700	3.743	EPSD	TCGA;ICGC;COSMIC	8.148	Loss
CMGC_CDK_CDK2_CDK2_ST	O14686	KMT2D	P24941	CDK2	S1939	M1941V	1941	Missense	proximal	2	no	13.700	13.612	EPSD	TCGA;ICGC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	O14686	KMT2D	P24941	CDK2	S1939	G1946A	1946	Missense	distal	7	no	13.700	13.415	EPSD	TCGA;ICGC;COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	O14686	KMT2D	P24941	CDK2	S1950	F1952L	1952	Missense	proximal	2	no	11.653	11.295	EPSD	TCGA;ICGC;COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	O14686	KMT2D	P24941	CDK2	S1950	G1946A	1946	Missense	distal	-4	no	11.653	11.912	EPSD	TCGA;ICGC;COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	O14686	KMT2D	P24941	CDK2	S2115	L2113P	2113	Missense	proximal	-2	no	13.355	13.579	EPSD	TCGA;ICGC;COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	O14686	KMT2D	P24941	CDK2	S2128	A2133T	2133	Missense	distal	5	no	15.799	15.763	EPSD	TCGA;ICGC;COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	O14686	KMT2D	P24941	CDK2	T2131	A2133T	2133	Missense	proximal	2	no	13.619	13.417	EPSD	TCGA;ICGC;COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	O14686	KMT2D	P24941	CDK2	T2131	S2136P	2136	Missense	distal	5	no	13.619	13.720	EPSD	TCGA;ICGC;COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	O14686	KMT2D	P24941	CDK2	S2155	S2149L	2149	Missense	distal	-6	no	14.883	14.884	EPSD	TCGA;ICGC;COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	O14686	KMT2D	P24941	CDK2	S2201	P2202S	2202	Missense	proximal	1	no	10.968	-0.297	EPSD	TCGA;ICGC;COSMIC	8.148	Loss
CMGC_CDK_CDK2_CDK2_ST	O14686	KMT2D	P24941	CDK2	S2201	T2203K	2203	Missense	proximal	2	no	10.968	11.005	EPSD	TCGA;ICGC;COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	O14686	KMT2D	P24941	CDK2	S2201	P2200H	2200	Missense	proximal	-1	no	10.968	11.088	EPSD	TCGA;ICGC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	O14686	KMT2D	P24941	CDK2	T2229	G2232S	2232	Missense	distal	3	no	14.167	14.302	EPSD	TCGA;ICGC;COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	O14686	KMT2D	P24941	CDK2	T2233	G2232S	2232	Missense	proximal	-1	no	15.488	13.968	EPSD	TCGA;ICGC;COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	O14686	KMT2D	P24941	CDK2	S2260	E2259K	2259	Missense	proximal	-1	no	14.092	13.206	EPSD	TCGA;ICGC;COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	O14686	KMT2D	P24941	CDK2	S2260	E2259D	2259	Missense	proximal	-1	no	14.092	14.062	EPSD	TCGA;ICGC;COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	O14686	KMT2D	P24941	CDK2	S2274	P2276S	2276	Missense	proximal	2	no	12.104	12.170	EPSD	TCGA;ICGC;COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	O14686	KMT2D	P24941	CDK2	S2274	P2271L	2271	Missense	distal	-3	no	12.104	12.033	EPSD	TCGA;ICGC;COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	O14686	KMT2D	P24941	CDK2	S2274	S2274L	2274	Missense	central	0	yes	12.104	0.000	EPSD	TCGA;ICGC;COSMIC	8.148	Loss
CMGC_CDK_CDK2_CDK2_ST	O14686	KMT2D	P24941	CDK2	S2274	P2275L	2275	Missense	proximal	1	no	12.104	2.283	EPSD	TCGA;ICGC;COSMIC	8.148	Loss
CMGC_CDK_CDK2_CDK2_ST	O14686	KMT2D	P24941	CDK2	S2296	P2301L	2301	Missense	distal	5	no	12.463	12.503	EPSD	TCGA;ICGC;COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	O14686	KMT2D	P24941	CDK2	S2296	P2301S	2301	Missense	distal	5	no	12.463	12.362	EPSD	TCGA;ICGC;COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	O14686	KMT2D	P24941	CDK2	S2296	S2296Y	2296	Missense	central	0	yes	12.463	0.000	EPSD	TCGA;ICGC	8.148	Loss
CMGC_CDK_CDK2_CDK2_ST	O14686	KMT2D	P24941	CDK2	S2309	S2311F	2311	Missense	proximal	2	no	12.848	13.033	EPSD	TCGA;ICGC;COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	O14686	KMT2D	P24941	CDK2	S2309	S2312L	2312	Missense	distal	3	no	12.848	12.431	EPSD	TCGA;ICGC;COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	O14686	KMT2D	P24941	CDK2	S2309	H2315Q	2315	Missense	distal	6	no	12.848	12.859	EPSD	TCGA;ICGC;COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	O14686	KMT2D	P24941	CDK2	S2309	P2310L	2310	Missense	proximal	1	no	12.848	3.027	EPSD	TCGA;ICGC;COSMIC	8.148	Loss
CMGC_CDK_CDK2_CDK2_ST	O14686	KMT2D	P24941	CDK2	S2312	S2311F	2311	Missense	proximal	-1	no	10.265	11.522	EPSD	TCGA;ICGC;COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	O14686	KMT2D	P24941	CDK2	S2312	S2312L	2312	Missense	central	0	yes	10.265	0.000	EPSD	TCGA;ICGC;COSMIC	8.148	Loss
CMGC_CDK_CDK2_CDK2_ST	O14686	KMT2D	P24941	CDK2	S2312	H2315Q	2315	Missense	distal	3	no	10.265	9.218	EPSD	TCGA;ICGC;COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	O14686	KMT2D	P24941	CDK2	S2312	P2310L	2310	Missense	proximal	-2	no	10.265	10.041	EPSD	TCGA;ICGC;COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	O14686	KMT2D	P24941	CDK2	T2323	D2325N	2325	Missense	proximal	2	no	14.175	14.107	EPSD	TCGA;ICGC;COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	O14686	KMT2D	P24941	CDK2	T2332	D2325N	2325	Missense	distal	-7	no	11.648	11.325	EPSD	TCGA;ICGC;COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	O14686	KMT2D	P24941	CDK2	T2332	Q2337E	2337	Missense	distal	5	no	11.648	11.767	EPSD	TCGA;ICGC;COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	O14686	KMT2D	P24941	CDK2	T2332	R2334W	2334	Missense	proximal	2	no	11.648	11.745	EPSD	TCGA;ICGC;COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	O14686	KMT2D	P24941	CDK2	T2332	R2334Q	2334	Missense	proximal	2	no	11.648	11.548	EPSD	TCGA;ICGC;COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	O14686	KMT2D	P24941	CDK2	S2342	Q2337E	2337	Missense	distal	-5	no	14.397	14.434	EPSD	TCGA;ICGC;COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	O14686	KMT2D	P24941	CDK2	S2342	P2340S	2340	Missense	proximal	-2	no	14.397	13.745	EPSD	TCGA	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	O14686	KMT2D	P24941	CDK2	S2414	S2417F	2417	Missense	distal	3	no	12.864	12.789	EPSD	TCGA;ICGC;COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	O14686	KMT2D	P24941	CDK2	S2414	P2407H	2407	Missense	distal	-7	no	12.864	12.988	EPSD	TCGA;ICGC;COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	O14686	KMT2D	P24941	CDK2	S2423	S2417F	2417	Missense	distal	-6	no	13.612	13.617	EPSD	TCGA;ICGC;COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	O14686	KMT2D	P24941	CDK2	S2438	V2440I	2440	Missense	proximal	2	no	10.891	10.746	EPSD	TCGA;ICGC;COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	O14686	KMT2D	P24941	CDK2	S2438	R2443H	2443	Missense	distal	5	no	10.891	10.863	EPSD	TCGA;ICGC;COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	O14686	KMT2D	P24941	CDK2	S2446	R2452H	2452	Missense	distal	6	no	11.826	11.837	EPSD	TCGA;ICGC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	O14686	KMT2D	P24941	CDK2	S2446	R2443H	2443	Missense	distal	-3	no	11.826	11.783	EPSD	TCGA;ICGC;COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	O14686	KMT2D	P24941	CDK2	S2592	S2590L	2590	Missense	proximal	-2	no	13.596	14.022	EPSD	TCGA;COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	O14686	KMT2D	P24941	CDK2	S2608	R2611C	2611	Missense	distal	3	no	14.981	8.617	EPSD	TCGA;ICGC;COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	O14686	KMT2D	P24941	CDK2	S2608	T2601I	2601	Missense	distal	-7	no	14.981	15.178	EPSD	TCGA;ICGC;COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	O14686	KMT2D	P24941	CDK2	S2608	S2604G	2604	Missense	distal	-4	no	14.981	14.309	EPSD	TCGA;ICGC;COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	O14686	KMT2D	P24941	CDK2	T2664	S2670F	2670	Missense	distal	6	no	8.390	8.371	EPSD	TCGA	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	O14686	KMT2D	P24941	CDK2	T2664	L2661H	2661	Missense	distal	-3	no	8.390	8.607	EPSD	TCGA;ICGC;COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	O14686	KMT2D	P24941	CDK2	T2664	G2668C	2668	Missense	distal	4	no	8.390	7.763	EPSD	TCGA;ICGC;COSMIC	8.148	Loss
CMGC_CDK_CDK2_CDK2_ST	O14686	KMT2D	P24941	CDK2	S2726	A2728V	2728	Missense	proximal	2	no	13.529	13.627	EPSD	TCGA;ICGC;COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	O14686	KMT2D	P24941	CDK2	S2726	E2723K	2723	Missense	distal	-3	no	13.529	13.314	EPSD	TCGA	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	O14686	KMT2D	P24941	CDK2	T2737	Q2743H	2743	Missense	distal	6	no	13.241	13.230	EPSD	TCGA;ICGC;COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	O14686	KMT2D	P24941	CDK2	T2737	R2734Q	2734	Missense	distal	-3	no	13.241	13.110	EPSD	TCGA;ICGC;COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	O14686	KMT2D	P24941	CDK2	T2742	Q2743H	2743	Missense	proximal	1	no	9.069	10.222	EPSD	TCGA;ICGC;COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	O14686	KMT2D	P24941	CDK2	T2780	R2774W	2774	Missense	distal	-6	no	10.771	10.777	EPSD	TCGA;ICGC;COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	O14686	KMT2D	P24941	CDK2	S2852	S2858F	2858	Missense	distal	6	no	15.356	15.337	EPSD	TCGA;ICGC;COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	O14686	KMT2D	P24941	CDK2	S2852	A2849V	2849	Missense	distal	-3	no	15.356	15.558	EPSD	TCGA;ICGC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	O14686	KMT2D	P24941	CDK2	T2949	N2944K	2944	Missense	distal	-5	no	12.037	12.020	EPSD	TCGA;ICGC;COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	O14686	KMT2D	P24941	CDK2	T2959	V2964F	2964	Missense	distal	5	no	8.464	8.715	EPSD	TCGA;ICGC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	O14686	KMT2D	P24941	CDK2	T2959	R2966W	2966	Missense	distal	7	no	8.464	8.864	EPSD	TCGA;ICGC;COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	O14686	KMT2D	P24941	CDK2	S3130	E3124K	3124	Missense	distal	-6	no	15.075	15.073	EPSD	TCGA;ICGC;COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	O14686	KMT2D	P24941	CDK2	T3138	A3144T	3144	Missense	distal	6	no	12.165	12.177	EPSD	TCGA;ICGC;COSMIC;GDSC;CCLE	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	O14686	KMT2D	P24941	CDK2	T3197	S3199N	3199	Missense	proximal	2	no	16.499	16.362	EPSD	TCGA;ICGC;COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	O14686	KMT2D	P24941	CDK2	S3199	G3205V	3205	Missense	distal	6	no	14.490	14.500	EPSD	TCGA;ICGC;COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	O14686	KMT2D	P24941	CDK2	S3199	S3199N	3199	Missense	central	0	yes	14.490	0.000	EPSD	TCGA;ICGC;COSMIC	8.148	Loss
CMGC_CDK_CDK2_CDK2_ST	O14686	KMT2D	P24941	CDK2	S3478	Q3471H	3471	Missense	distal	-7	no	8.737	8.903	EPSD	TCGA;ICGC;COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	O14686	KMT2D	P24941	CDK2	S3478	A3475T	3475	Missense	distal	-3	no	8.737	8.756	EPSD	TCGA;ICGC;COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	O14686	KMT2D	P24941	CDK2	S3620	L3619F	3619	Missense	proximal	-1	no	13.898	14.863	EPSD	TCGA;ICGC;COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	O14686	KMT2D	P24941	CDK2	S3624	L3619F	3619	Missense	distal	-5	no	12.661	12.721	EPSD	TCGA;ICGC;COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	O14686	KMT2D	P24941	CDK2	S3837	G3844V	3844	Missense	distal	7	no	13.020	12.608	EPSD	TCGA;ICGC;COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	O14686	KMT2D	P24941	CDK2	S3986	R3982Q	3982	Missense	distal	-4	no	12.479	12.504	EPSD	TCGA;ICGC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	O14686	KMT2D	P24941	CDK2	S4011	G4013E	4013	Missense	proximal	2	no	10.269	10.248	EPSD	TCGA;ICGC;COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	O14686	KMT2D	P24941	CDK2	S4215	P4216S	4216	Missense	proximal	1	no	12.661	1.395	EPSD	TCGA;ICGC;COSMIC	8.148	Loss
CMGC_CDK_CDK2_CDK2_ST	O14686	KMT2D	P24941	CDK2	T4308	L4302F	4302	Missense	distal	-6	no	11.652	11.656	EPSD	TCGA;ICGC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	O14686	KMT2D	P24941	CDK2	S4313	R4319I	4319	Missense	distal	6	no	14.715	14.732	EPSD	TCGA;ICGC;COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	O14686	KMT2D	P24941	CDK2	S4325	R4319I	4319	Missense	distal	-6	no	14.343	14.344	EPSD	TCGA;ICGC;COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	O14686	KMT2D	P24941	CDK2	S4325	Q4329H	4329	Missense	distal	4	no	14.343	14.045	EPSD	TCGA;ICGC;COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	O14686	KMT2D	P24941	CDK2	S4325	P4331S	4331	Missense	distal	6	no	14.343	14.345	EPSD	TCGA;ICGC;COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	O14686	KMT2D	P24941	CDK2	T4343	G4342V	4342	Missense	proximal	-1	no	13.746	12.654	EPSD	TCGA;ICGC;COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	O14686	KMT2D	P24941	CDK2	T4343	P4344S	4344	Missense	proximal	1	no	13.746	2.480	EPSD	TCGA;ICGC;COSMIC	8.148	Loss
CMGC_CDK_CDK2_CDK2_ST	O14686	KMT2D	P24941	CDK2	S4359	S4359L	4359	Missense	central	0	yes	11.461	0.000	EPSD	TCGA;ICGC;COSMIC	8.148	Loss
CMGC_CDK_CDK2_CDK2_ST	O14686	KMT2D	P24941	CDK2	S4359	G4356E	4356	Missense	distal	-3	no	11.461	11.532	EPSD	TCGA;ICGC;COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	O14686	KMT2D	P24941	CDK2	S4359	P4354S	4354	Missense	distal	-5	no	11.461	11.416	EPSD	TCGA;ICGC;COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	O14686	KMT2D	P24941	CDK2	T4505	P4506S	4506	Missense	proximal	1	no	14.516	3.250	EPSD	TCGA;ICGC;COSMIC;GDSC;CCLE	8.148	Loss
CMGC_CDK_CDK2_CDK2_ST	O14686	KMT2D	P24941	CDK2	T4643	E4646K	4646	Missense	distal	3	no	13.882	15.967	EPSD	TCGA;ICGC;COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	O14686	KMT2D	P24941	CDK2	S4738	E4731D	4731	Missense	distal	-7	no	14.964	15.115	EPSD	TCGA	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	O14686	KMT2D	P24941	CDK2	S4822	V4817M	4817	Missense	distal	-5	no	15.361	15.436	EPSD	TCGA;ICGC;COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	O14686	KMT2D	P24941	CDK2	S4822	P4820S	4820	Missense	proximal	-2	no	15.361	14.709	EPSD	TCGA;ICGC;COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	O14686	KMT2D	P24941	CDK2	S4822	G4827D	4827	Missense	distal	5	no	15.361	15.408	EPSD	TCGA	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	O14686	KMT2D	P24941	CDK2	S4849	D4855H	4855	Missense	distal	6	no	13.011	13.021	EPSD	TCGA;ICGC;COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	O14686	KMT2D	P24941	CDK2	S4849	G4847V	4847	Missense	proximal	-2	no	13.011	13.104	EPSD	TCGA;ICGC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	O14686	KMT2D	P24941	CDK2	S4849	S4849G	4849	Missense	central	0	yes	13.011	0.000	EPSD	TCGA;ICGC;COSMIC	8.148	Loss
CMGC_CDK_CDK2_CDK2_ST	O14686	KMT2D	P24941	CDK2	S4883	E4887Q	4887	Missense	distal	4	no	15.576	15.620	EPSD	TCGA;ICGC;COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	O14686	KMT2D	P24941	CDK2	S4955	S4955F	4955	Missense	central	0	yes	13.119	0.000	EPSD	TCGA;ICGC;COSMIC	8.148	Loss
CMGC_CDK_CDK2_CDK2_ST	O14686	KMT2D	P24941	CDK2	S4955	A4959V	4959	Missense	distal	4	no	13.119	13.306	EPSD	TCGA;ICGC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	O14686	KMT2D	P24941	CDK2	T5347	R5351L	5351	Missense	distal	4	no	11.255	11.487	EPSD	TCGA;ICGC;COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	O14686	KMT2D	P24941	CDK2	T5347	R5351Q	5351	Missense	distal	4	no	11.255	11.437	EPSD	TCGA;ICGC;COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	P29590	PML	P24941	CDK2	S40	A47T	47	Missense	distal	7	no	13.816	13.128	EPSD	TCGA;ICGC;COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	P29590	PML	P24941	CDK2	T196	R195C	195	Missense	proximal	-1	no	14.219	13.522	EPSD	TCGA;ICGC;COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	P29590	PML	P24941	CDK2	T196	S190C	190	Missense	distal	-6	no	14.219	14.225	EPSD	TCGA;ICGC;COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	P29590	PML	P24941	CDK2	T196	R195H	195	Missense	proximal	-1	no	14.219	13.768	EPSD	TCGA;ICGC;COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	P29590	PML	P24941	CDK2	S221	L217H	217	Missense	distal	-4	no	8.287	7.741	EPSD	TCGA;ICGC;COSMIC	8.148	Loss
CMGC_CDK_CDK2_CDK2_ST	P29590	PML	P24941	CDK2	S221	A216T	216	Missense	distal	-5	no	8.287	8.261	EPSD	TCGA;ICGC;COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	P29590	PML	P24941	CDK2	S403	P410S	410	Missense	distal	7	no	15.136	14.984	EPSD	TCGA;ICGC;COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	P29590	PML	P24941	CDK2	S403	E405K	405	Missense	proximal	2	no	15.136	14.898	EPSD	TCGA;ICGC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	P29590	PML	P24941	CDK2	T409	P410S	410	Missense	proximal	1	no	12.973	1.707	EPSD	TCGA;ICGC;COSMIC	8.148	Loss
CMGC_CDK_CDK2_CDK2_ST	P29590	PML	P24941	CDK2	T409	E405K	405	Missense	distal	-4	no	12.973	12.662	EPSD	TCGA;ICGC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	P29590	PML	P24941	CDK2	T409	P413L	413	Missense	distal	4	no	12.973	13.085	EPSD	TCGA;ICGC;COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	P29590	PML	P24941	CDK2	S505	L501F	501	Missense	distal	-4	no	11.013	10.463	EPSD	TCGA;ICGC;COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	P29590	PML	P24941	CDK2	S518	S518L	518	Missense	central	0	yes	16.502	0.000	PhosphoSitePlus	TCGA;ICGC;COSMIC	8.148	Loss
CMGC_CDK_CDK2_CDK2_ST	P29590	PML	P24941	CDK2	T867	R861L	861	Missense	distal	-6	no	12.361	12.359	EPSD	TCGA;ICGC;COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	Q13242	SRSF9	P24941	CDK2	S109	R107T	107	Missense	proximal	-2	no	9.381	10.583	EPSD	TCGA;ICGC;COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	Q13242	SRSF9	P24941	CDK2	S109	S109F	109	Missense	central	0	yes	9.381	0.000	EPSD	TCGA;ICGC;COSMIC	8.148	Loss
CMGC_CDK_CDK2_CDK2_ST	Q13242	SRSF9	P24941	CDK2	S109	R108K	108	Missense	proximal	-1	no	9.381	8.710	EPSD	TCGA	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	Q13242	SRSF9	P24941	CDK2	S197	R202H	202	Missense	distal	5	no	9.099	9.071	EPSD	TCGA;ICGC;COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	Q13242	SRSF9	P24941	CDK2	S197	R196W	196	Missense	proximal	-1	no	9.099	9.653	EPSD	TCGA;ICGC;COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	Q13242	SRSF9	P24941	CDK2	S204	R202H	202	Missense	proximal	-2	no	14.197	14.423	EPSD	TCGA;ICGC;COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	Q13242	SRSF9	P24941	CDK2	S211	F218L	218	Missense	distal	7	no	14.174	13.502	EPSD	TCGA;ICGC;COSMIC;CCLE	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	Q13242	SRSF9	P24941	CDK2	S216	F218L	218	Missense	proximal	2	no	17.779	17.421	PhosphoSitePlus	TCGA;ICGC;COSMIC;CCLE	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	Q05682	CALD1	P24941	CDK2	T86	D92Y	92	Missense	distal	6	no	9.164	9.171	EPSD	TCGA;COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	Q05682	CALD1	P24941	CDK2	S171	Y172H	172	Missense	proximal	1	no	2.164	10.904	EPSD	TCGA;COSMIC	8.148	Gain
CMGC_CDK_CDK2_CDK2_ST	Q05682	CALD1	P24941	CDK2	S248	H254N	254	Missense	distal	6	no	8.295	8.303	EPSD	TCGA;ICGC;COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	Q05682	CALD1	P24941	CDK2	S248	S252F	252	Missense	distal	4	no	8.295	8.099	EPSD	TCGA;ICGC;COSMIC	8.148	Loss
CMGC_CDK_CDK2_CDK2_ST	Q05682	CALD1	P24941	CDK2	S252	H254N	254	Missense	proximal	2	no	8.892	8.744	EPSD	TCGA;ICGC;COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	Q05682	CALD1	P24941	CDK2	S252	S252F	252	Missense	central	0	yes	8.892	0.000	EPSD	TCGA;ICGC;COSMIC	8.148	Loss
CMGC_CDK_CDK2_CDK2_ST	Q05682	CALD1	P24941	CDK2	T638	S643Y	643	Missense	distal	5	no	9.956	10.130	EPSD	TCGA;COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	Q05682	CALD1	P24941	CDK2	T638	S643F	643	Missense	distal	5	no	9.956	10.275	EPSD	TCGA;COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	Q05682	CALD1	P24941	CDK2	T638	K631N	631	Missense	distal	-7	no	9.956	9.922	EPSD	TCGA;COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	Q05682	CALD1	P24941	CDK2	T638	F634C	634	Missense	distal	-4	no	9.956	9.812	EPSD	TCGA;COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	Q05682	CALD1	P24941	CDK2	S661	S665L	665	Missense	distal	4	no	8.169	8.268	EPSD	TCGA;COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	Q05682	CALD1	P24941	CDK2	S661	S660R	660	Missense	proximal	-1	no	8.169	9.211	EPSD	TCGA;COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	Q05682	CALD1	P24941	CDK2	S661	V663G	663	Missense	proximal	2	no	8.169	8.164	EPSD	TCGA;COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	Q05682	CALD1	P24941	CDK2	S661	Q668K	668	Missense	distal	7	no	8.169	8.037	EPSD	TCGA;COSMIC	8.148	Loss
CMGC_CDK_CDK2_CDK2_ST	Q05682	CALD1	P24941	CDK2	S677	E680K	680	Missense	distal	3	no	6.265	8.350	EPSD	TCGA;COSMIC	8.148	Gain
CMGC_CDK_CDK2_CDK2_ST	Q05682	CALD1	P24941	CDK2	S759	S765Y	765	Missense	distal	6	no	13.252	13.242	EPSD	TCGA	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	P49916	LIG3	P24941	CDK2	T191	K193T	193	Missense	proximal	2	no	17.328	17.291	PhosphoSitePlus;EPSD	TCGA;ICGC;COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	P49916	LIG3	P24941	CDK2	S210	V212L	212	Missense	proximal	2	no	16.775	16.546	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	P49916	LIG3	P24941	CDK2	S242	S236C	236	Missense	distal	-6	no	11.280	11.286	EPSD	TCGA;ICGC;COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	P49916	LIG3	P24941	CDK2	S242	E238K	238	Missense	distal	-4	no	11.280	10.968	EPSD	TCGA;ICGC;COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	P49916	LIG3	P24941	CDK2	T244	E238K	238	Missense	distal	-6	no	14.796	14.794	EPSD	TCGA;ICGC;COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	P49916	LIG3	P24941	CDK2	T479	S476L	476	Missense	distal	-3	no	16.156	15.989	EPSD	TCGA;ICGC;COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	P49916	LIG3	P24941	CDK2	T479	A475S	475	Missense	distal	-4	no	16.156	16.569	EPSD	TCGA;ICGC;COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	P49916	LIG3	P24941	CDK2	T479	A486V	486	Missense	distal	7	no	16.156	16.029	EPSD	TCGA;ICGC;COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	P49916	LIG3	P24941	CDK2	S913	V915L	915	Missense	proximal	2	no	17.288	17.059	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	P48634	PRRC2A	P24941	CDK2	T116	Q115H	115	Missense	proximal	-1	no	10.231	10.658	EPSD	TCGA;ICGC;COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	P48634	PRRC2A	P24941	CDK2	T116	P122L	122	Missense	distal	6	no	10.231	10.233	EPSD	TCGA;ICGC;COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	P48634	PRRC2A	P24941	CDK2	T116	L111R	111	Missense	distal	-5	no	10.231	10.266	EPSD	TCGA;ICGC;COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	P48634	PRRC2A	P24941	CDK2	T116	T116M	116	Missense	central	0	yes	10.231	0.000	EPSD	TCGA;ICGC	8.148	Loss
CMGC_CDK_CDK2_CDK2_ST	P48634	PRRC2A	P24941	CDK2	S193	G196R	196	Missense	distal	3	no	6.939	8.758	EPSD	TCGA;ICGC;COSMIC	8.148	Gain
CMGC_CDK_CDK2_CDK2_ST	P48634	PRRC2A	P24941	CDK2	S365	E367K	367	Missense	proximal	2	no	8.825	8.587	EPSD	TCGA;ICGC;COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	P48634	PRRC2A	P24941	CDK2	S380	G375S	375	Missense	distal	-5	no	10.568	10.444	EPSD	TCGA;ICGC;COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	P48634	PRRC2A	P24941	CDK2	S380	P385L	385	Missense	distal	5	no	10.568	10.608	EPSD	TCGA;ICGC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	P48634	PRRC2A	P24941	CDK2	S380	S380F	380	Missense	central	0	yes	10.568	0.000	EPSD	TCGA;ICGC;COSMIC	8.148	Loss
CMGC_CDK_CDK2_CDK2_ST	P48634	PRRC2A	P24941	CDK2	S380	P385T	385	Missense	distal	5	no	10.568	10.542	EPSD	TCGA;ICGC;COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	P48634	PRRC2A	P24941	CDK2	T387	A393E	393	Missense	distal	6	no	14.116	14.118	EPSD	TCGA;ICGC;COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	P48634	PRRC2A	P24941	CDK2	T387	P385L	385	Missense	proximal	-2	no	14.116	13.892	EPSD	TCGA;ICGC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	P48634	PRRC2A	P24941	CDK2	T387	S380F	380	Missense	distal	-7	no	14.116	14.668	EPSD	TCGA;ICGC;COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	P48634	PRRC2A	P24941	CDK2	T387	P388L	388	Missense	proximal	1	no	14.116	4.295	EPSD	TCGA;ICGC;COSMIC	8.148	Loss
CMGC_CDK_CDK2_CDK2_ST	P48634	PRRC2A	P24941	CDK2	T387	P385T	385	Missense	proximal	-2	no	14.116	14.083	EPSD	TCGA;ICGC;COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	P48634	PRRC2A	P24941	CDK2	T387	T390M	390	Missense	distal	3	no	14.116	13.991	EPSD	TCGA;ICGC;COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	P48634	PRRC2A	P24941	CDK2	T387	A391T	391	Missense	distal	4	no	14.116	14.359	EPSD	TCGA;ICGC;COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	P48634	PRRC2A	P24941	CDK2	S457	S458P	458	Missense	proximal	1	no	3.253	14.519	EPSD	TCGA;ICGC;COSMIC	8.148	Gain
CMGC_CDK_CDK2_CDK2_ST	P48634	PRRC2A	P24941	CDK2	T517	S516C	516	Missense	proximal	-1	no	12.943	13.287	EPSD	TCGA;ICGC;COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	P48634	PRRC2A	P24941	CDK2	T517	P522S	522	Missense	distal	5	no	12.943	12.842	EPSD	TCGA;ICGC;COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	P48634	PRRC2A	P24941	CDK2	T610	P606L	606	Missense	distal	-4	no	12.989	12.931	EPSD	TCGA;ICGC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	P48634	PRRC2A	P24941	CDK2	T610	E617D	617	Missense	distal	7	no	12.989	13.631	EPSD	TCGA;ICGC;COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	P48634	PRRC2A	P24941	CDK2	T610	P606S	606	Missense	distal	-4	no	12.989	13.344	EPSD	TCGA;ICGC;COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	P48634	PRRC2A	P24941	CDK2	T610	P614S	614	Missense	distal	4	no	12.989	13.002	EPSD	TCGA;ICGC;COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	P48634	PRRC2A	P24941	CDK2	T610	P608H	608	Missense	proximal	-2	no	12.989	11.979	EPSD	TCGA;ICGC;COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	P48634	PRRC2A	P24941	CDK2	S761	S766T	766	Missense	distal	5	no	8.111	8.187	EPSD	TCGA;ICGC;COSMIC	8.148	Gain
CMGC_CDK_CDK2_CDK2_ST	P48634	PRRC2A	P24941	CDK2	T799	D794H	794	Missense	distal	-5	no	14.750	14.739	EPSD	TCGA;ICGC;COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	P48634	PRRC2A	P24941	CDK2	T799	F796L	796	Missense	distal	-3	no	14.750	14.492	EPSD	TCGA;ICGC;COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	P48634	PRRC2A	P24941	CDK2	T799	R804H	804	Missense	distal	5	no	14.750	14.721	EPSD	TCGA;ICGC;COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	P48634	PRRC2A	P24941	CDK2	S808	L810V	810	Missense	proximal	2	no	16.000	16.229	EPSD	TCGA;ICGC;COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	P48634	PRRC2A	P24941	CDK2	S808	R804H	804	Missense	distal	-4	no	16.000	15.639	EPSD	TCGA;ICGC;COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	P48634	PRRC2A	P24941	CDK2	T825	S823N	823	Missense	proximal	-2	no	15.990	15.298	EPSD	TCGA;ICGC;COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	P48634	PRRC2A	P24941	CDK2	T825	P826S	826	Missense	proximal	1	no	15.990	4.724	EPSD	TCGA;ICGC;COSMIC;GDSC;CCLE	8.148	Loss
CMGC_CDK_CDK2_CDK2_ST	P48634	PRRC2A	P24941	CDK2	T878	D871N	871	Missense	distal	-7	no	15.249	14.926	EPSD	TCGA;ICGC;COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	P48634	PRRC2A	P24941	CDK2	T878	E872A	872	Missense	distal	-6	no	15.249	15.245	EPSD	TCGA;ICGC;COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	P48634	PRRC2A	P24941	CDK2	T975	E974K	974	Missense	proximal	-1	no	13.110	12.225	EPSD	TCGA;ICGC;COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	P48634	PRRC2A	P24941	CDK2	T975	D982Y	982	Missense	distal	7	no	13.110	12.693	EPSD	TCGA;ICGC;COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	P48634	PRRC2A	P24941	CDK2	T975	P968S	968	Missense	distal	-7	no	13.110	12.930	EPSD	TCGA;ICGC;COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	P48634	PRRC2A	P24941	CDK2	T975	E970K	970	Missense	distal	-5	no	13.110	13.075	EPSD	TCGA;ICGC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	P48634	PRRC2A	P24941	CDK2	T997	G992R	992	Missense	distal	-5	no	12.624	12.591	EPSD	TCGA;ICGC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	P48634	PRRC2A	P24941	CDK2	T997	L1003F	1003	Missense	distal	6	no	12.624	12.605	EPSD	TCGA;ICGC;COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	P48634	PRRC2A	P24941	CDK2	S1004	L1003F	1003	Missense	proximal	-1	no	15.107	16.072	EPSD	TCGA;ICGC;COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	P48634	PRRC2A	P24941	CDK2	S1092	E1095K	1095	Missense	distal	3	no	7.119	9.205	EPSD	TCGA;ICGC;COSMIC	8.148	Gain
CMGC_CDK_CDK2_CDK2_ST	P48634	PRRC2A	P24941	CDK2	S1092	E1093G	1093	Missense	proximal	1	no	7.119	8.973	EPSD	TCGA;ICGC;COSMIC;GDSC;CCLE	8.148	Gain
CMGC_CDK_CDK2_CDK2_ST	P48634	PRRC2A	P24941	CDK2	T1108	S1106L	1106	Missense	proximal	-2	no	9.643	10.070	EPSD	TCGA;ICGC;COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	P48634	PRRC2A	P24941	CDK2	T1126	E1123A	1123	Missense	distal	-3	no	12.069	11.836	EPSD	TCGA	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	P48634	PRRC2A	P24941	CDK2	T1126	T1133I	1133	Missense	distal	7	no	12.069	12.430	EPSD	TCGA;ICGC;COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	P48634	PRRC2A	P24941	CDK2	S1147	G1143A	1143	Missense	distal	-4	no	12.992	13.252	EPSD	TCGA;ICGC;COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	P48634	PRRC2A	P24941	CDK2	S1147	R1152C	1152	Missense	distal	5	no	12.992	13.120	EPSD	TCGA;ICGC;COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	P48634	PRRC2A	P24941	CDK2	S1186	P1188L	1188	Missense	proximal	2	no	12.590	12.483	EPSD	TCGA;ICGC;COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	P48634	PRRC2A	P24941	CDK2	S1186	P1179L	1179	Missense	distal	-7	no	12.590	12.595	EPSD	TCGA;ICGC;COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	P48634	PRRC2A	P24941	CDK2	S1186	S1191Y	1191	Missense	distal	5	no	12.590	12.764	EPSD	TCGA;ICGC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	P48634	PRRC2A	P24941	CDK2	S1306	A1304S	1304	Missense	proximal	-2	no	14.241	13.574	EPSD	TCGA;ICGC;COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	P48634	PRRC2A	P24941	CDK2	S1306	S1306F	1306	Missense	central	0	yes	14.241	0.000	EPSD	TCGA;ICGC;COSMIC	8.148	Loss
CMGC_CDK_CDK2_CDK2_ST	P48634	PRRC2A	P24941	CDK2	T1347	P1354A	1354	Missense	distal	7	no	12.543	12.927	EPSD	TCGA;ICGC;COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	P48634	PRRC2A	P24941	CDK2	T1347	V1351M	1351	Missense	distal	4	no	12.543	11.895	EPSD	TCGA;ICGC;COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	P48634	PRRC2A	P24941	CDK2	T1347	G1352E	1352	Missense	distal	5	no	12.543	12.495	EPSD	TCGA;ICGC;COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	P48634	PRRC2A	P24941	CDK2	T1347	P1354S	1354	Missense	distal	7	no	12.543	12.391	EPSD	TCGA;ICGC;COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	P48634	PRRC2A	P24941	CDK2	T1353	P1354A	1354	Missense	proximal	1	no	12.562	-1.841	PhosphoSitePlus	TCGA;ICGC;COSMIC	8.148	Loss
CMGC_CDK_CDK2_CDK2_ST	P48634	PRRC2A	P24941	CDK2	T1353	G1360A	1360	Missense	distal	7	no	12.562	12.277	PhosphoSitePlus	TCGA;ICGC;COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	P48634	PRRC2A	P24941	CDK2	T1353	V1351M	1351	Missense	proximal	-2	no	12.562	11.128	PhosphoSitePlus	TCGA;ICGC;COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	P48634	PRRC2A	P24941	CDK2	T1353	G1352E	1352	Missense	proximal	-1	no	12.562	12.299	PhosphoSitePlus	TCGA;ICGC;COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	P48634	PRRC2A	P24941	CDK2	T1353	P1354S	1354	Missense	proximal	1	no	12.562	1.297	PhosphoSitePlus	TCGA;ICGC;COSMIC	8.148	Loss
CMGC_CDK_CDK2_CDK2_ST	P48634	PRRC2A	P24941	CDK2	S1435	R1439P	1439	Missense	distal	4	no	10.150	10.271	EPSD	TCGA;ICGC;COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	P48634	PRRC2A	P24941	CDK2	S1435	R1441G	1441	Missense	distal	6	no	10.150	10.156	EPSD	TCGA;ICGC;COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	P48634	PRRC2A	P24941	CDK2	S1435	R1439L	1439	Missense	distal	4	no	10.150	10.383	EPSD	TCGA;ICGC;COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	P48634	PRRC2A	P24941	CDK2	S1554	G1552E	1552	Missense	proximal	-2	no	12.805	12.432	EPSD	TCGA	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	P48634	PRRC2A	P24941	CDK2	S1554	A1551S	1551	Missense	distal	-3	no	12.805	12.959	EPSD	TCGA;ICGC;COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	P48634	PRRC2A	P24941	CDK2	S1554	R1560C	1560	Missense	distal	6	no	12.805	12.808	EPSD	TCGA;ICGC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	P48634	PRRC2A	P24941	CDK2	T1607	R1613H	1613	Missense	distal	6	no	14.851	14.862	EPSD	TCGA;ICGC;COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	P48634	PRRC2A	P24941	CDK2	T1607	T1607P	1607	Missense	central	0	yes	14.851	0.000	EPSD	TCGA;ICGC	8.148	Loss
CMGC_CDK_CDK2_CDK2_ST	P48634	PRRC2A	P24941	CDK2	T1607	D1600H	1600	Missense	distal	-7	no	14.851	14.733	EPSD	TCGA;ICGC;COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	P48634	PRRC2A	P24941	CDK2	T1607	G1602C	1602	Missense	distal	-5	no	14.851	14.852	EPSD	TCGA;ICGC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	P48634	PRRC2A	P24941	CDK2	S1691	S1691L	1691	Missense	central	0	yes	10.207	0.000	EPSD	TCGA;ICGC;COSMIC	8.148	Loss
CMGC_CDK_CDK2_CDK2_ST	P48634	PRRC2A	P24941	CDK2	S1691	P1697A	1697	Missense	distal	6	no	10.207	10.203	EPSD	TCGA;ICGC;COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	P48634	PRRC2A	P24941	CDK2	T1868	R1865H	1865	Missense	distal	-3	no	14.167	14.125	EPSD	TCGA;ICGC;COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	P48634	PRRC2A	P24941	CDK2	T1868	P1866L	1866	Missense	proximal	-2	no	14.167	13.943	EPSD	TCGA;ICGC;COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	P48634	PRRC2A	P24941	CDK2	T1868	P1869L	1869	Missense	proximal	1	no	14.167	4.346	EPSD	TCGA;ICGC;COSMIC	8.148	Loss
CMGC_CDK_CDK2_CDK2_ST	P48634	PRRC2A	P24941	CDK2	S2036	L2034R	2034	Missense	proximal	-2	no	15.988	14.977	EPSD	TCGA;ICGC;COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	P48634	PRRC2A	P24941	CDK2	S2036	F2041L	2041	Missense	distal	5	no	15.988	15.811	EPSD	TCGA	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	P48634	PRRC2A	P24941	CDK2	T2076	G2080E	2080	Missense	distal	4	no	15.123	15.260	EPSD	TCGA;ICGC;COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	P48634	PRRC2A	P24941	CDK2	T2076	R2075Q	2075	Missense	proximal	-1	no	15.123	14.245	EPSD	TCGA;ICGC;COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	P48634	PRRC2A	P24941	CDK2	S2084	G2080E	2080	Missense	distal	-4	no	8.120	8.668	EPSD	TCGA;ICGC;COSMIC	8.148	Gain
CMGC_CDK_CDK2_CDK2_ST	P48634	PRRC2A	P24941	CDK2	S2084	R2089C	2089	Missense	distal	5	no	8.120	8.248	EPSD	TCGA;ICGC	8.148	Gain
CMGC_CDK_CDK2_CDK2_ST	P48634	PRRC2A	P24941	CDK2	T2093	R2089C	2089	Missense	distal	-4	no	13.815	13.306	EPSD	TCGA;ICGC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	P48634	PRRC2A	P24941	CDK2	S2113	A2117T	2117	Missense	distal	4	no	12.104	12.347	EPSD	TCGA;ICGC;COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	P48634	PRRC2A	P24941	CDK2	S2113	R2119C	2119	Missense	distal	6	no	12.104	12.107	EPSD	TCGA;ICGC;COSMIC;GDSC;CCLE	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	P48634	PRRC2A	P24941	CDK2	S2113	R2119H	2119	Missense	distal	6	no	12.104	12.115	EPSD	TCGA;ICGC;COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	P20248	CCNA2	P24941	CDK2	S154	F152V	152	Missense	proximal	-2	no	12.572	13.035	PhosphoSitePlus	TCGA;ICGC;COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	P20248	CCNA2	P24941	CDK2	S375	R378Q	378	Missense	distal	3	no	8.302	6.558	EPSD	TCGA;ICGC;COSMIC	8.148	Loss
CMGC_CDK_CDK2_CDK2_ST	P20248	CCNA2	P24941	CDK2	S375	R378G	378	Missense	distal	3	no	8.302	6.482	EPSD	TCGA;ICGC;COSMIC	8.148	Loss
CMGC_CDK_CDK2_CDK2_ST	O95251	KAT7	P24941	CDK2	S29	S30P	30	Missense	proximal	1	no	3.115	14.381	EPSD	TCGA;ICGC;COSMIC	8.148	Gain
CMGC_CDK_CDK2_CDK2_ST	O95251	KAT7	P24941	CDK2	S57	S50I	50	Missense	distal	-7	no	15.082	15.456	EPSD	TCGA;ICGC;COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	O95251	KAT7	P24941	CDK2	S57	D55N	55	Missense	proximal	-2	no	15.082	13.873	EPSD	TCGA;ICGC;COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	O95251	KAT7	P24941	CDK2	S57	S56F	56	Missense	proximal	-1	no	15.082	16.338	EPSD	TCGA;ICGC;COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	O95251	KAT7	P24941	CDK2	S57	N61T	61	Missense	distal	4	no	15.082	15.385	EPSD	TCGA;ICGC;COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	O95251	KAT7	P24941	CDK2	S57	S64Y	64	Missense	distal	7	no	15.082	15.503	EPSD	TCGA;ICGC;COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	O95251	KAT7	P24941	CDK2	S57	S52I	52	Missense	distal	-5	no	15.082	15.165	EPSD	TCGA;ICGC;COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	O95251	KAT7	P24941	CDK2	S57	R60Q	60	Missense	distal	3	no	15.082	13.338	EPSD	TCGA;ICGC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	O95251	KAT7	P24941	CDK2	S57	S64P	64	Missense	distal	7	no	15.082	15.234	EPSD	TCGA;ICGC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	O95251	KAT7	P24941	CDK2	T85	P89L	89	Missense	distal	4	no	13.330	13.441	EPSD	TCGA;ICGC;COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	O95251	KAT7	P24941	CDK2	T88	P89L	89	Missense	proximal	1	no	16.778	6.957	PhosphoSitePlus	TCGA;ICGC;COSMIC	8.148	Loss
CMGC_CDK_CDK2_CDK2_ST	O95251	KAT7	P24941	CDK2	T88	L94I	94	Missense	distal	6	no	16.778	16.777	PhosphoSitePlus	TCGA;ICGC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	O95251	KAT7	P24941	CDK2	S124	R127Q	127	Missense	distal	3	no	21.068	19.325	EPSD	TCGA;ICGC;COSMIC;GDSC;CCLE	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	O95251	KAT7	P24941	CDK2	T128	R127Q	127	Missense	proximal	-1	no	14.686	13.808	EPSD	TCGA;ICGC;COSMIC;GDSC;CCLE	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	O95251	KAT7	P24941	CDK2	T128	S135Y	135	Missense	distal	7	no	14.686	15.107	EPSD	TCGA;ICGC;COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	O95251	KAT7	P24941	CDK2	S144	H149Y	149	Missense	distal	5	no	15.147	15.142	EPSD	TCGA;ICGC;COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	O95251	KAT7	P24941	CDK2	S148	H149Y	149	Missense	proximal	1	no	10.590	1.849	EPSD	TCGA;ICGC;COSMIC	8.148	Loss
CMGC_CDK_CDK2_CDK2_ST	O95251	KAT7	P24941	CDK2	T187	F181L	181	Missense	distal	-6	no	8.322	8.318	EPSD	TCGA;ICGC;COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	O95251	KAT7	P24941	CDK2	S506	R509C	509	Missense	distal	3	no	17.327	10.962	EPSD	TCGA;COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	O95251	KAT7	P24941	CDK2	S506	K503N	503	Missense	distal	-3	no	17.327	17.388	EPSD	TCGA;COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	O95251	KAT7	P24941	CDK2	T606	P608L	608	Missense	proximal	2	no	17.421	17.314	EPSD	TCGA;COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	O15014	ZNF609	P24941	CDK2	S8	A15T	15	Missense	distal	7	no	8.358	7.669	EPSD	TCGA;ICGC;COSMIC	8.148	Loss
CMGC_CDK_CDK2_CDK2_ST	O15014	ZNF609	P24941	CDK2	S52	K55R	55	Missense	distal	3	no	8.368	7.379	EPSD	TCGA;ICGC;COSMIC	8.148	Loss
CMGC_CDK_CDK2_CDK2_ST	O15014	ZNF609	P24941	CDK2	S52	G53D	53	Missense	proximal	1	no	8.368	7.437	EPSD	TCGA;ICGC;COSMIC;GDSC;CCLE	8.148	Loss
CMGC_CDK_CDK2_CDK2_ST	O15014	ZNF609	P24941	CDK2	S52	G58E	58	Missense	distal	6	no	8.368	8.377	EPSD	TCGA;ICGC;COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	O15014	ZNF609	P24941	CDK2	T103	D98Y	98	Missense	distal	-5	no	12.980	12.946	EPSD	TCGA;ICGC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	O15014	ZNF609	P24941	CDK2	T103	P102L	102	Missense	proximal	-1	no	12.980	12.800	EPSD	TCGA;ICGC;COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	O15014	ZNF609	P24941	CDK2	T103	S107F	107	Missense	distal	4	no	12.980	12.784	EPSD	TCGA;ICGC;COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	O15014	ZNF609	P24941	CDK2	T110	S107F	107	Missense	distal	-3	no	14.818	14.910	EPSD	TCGA;ICGC;COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	O15014	ZNF609	P24941	CDK2	S252	S255F	255	Missense	distal	3	no	11.772	11.697	EPSD	TCGA;ICGC;COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	O15014	ZNF609	P24941	CDK2	T256	S255F	255	Missense	proximal	-1	no	15.112	16.368	EPSD	TCGA;ICGC;COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	O15014	ZNF609	P24941	CDK2	T256	L260V	260	Missense	distal	4	no	15.112	15.227	EPSD	TCGA;ICGC;COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	O15014	ZNF609	P24941	CDK2	S275	S275Y	275	Missense	central	0	yes	12.468	0.000	EPSD	TCGA;ICGC;COSMIC	8.148	Loss
CMGC_CDK_CDK2_CDK2_ST	O15014	ZNF609	P24941	CDK2	T381	R376C	376	Missense	distal	-5	no	10.192	10.225	EPSD	TCGA;ICGC;COSMIC;GDSC;CCLE	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	O15014	ZNF609	P24941	CDK2	T381	A387V	387	Missense	distal	6	no	10.192	10.194	EPSD	TCGA;ICGC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	O15014	ZNF609	P24941	CDK2	S390	A387V	387	Missense	distal	-3	no	8.528	8.729	EPSD	TCGA;ICGC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	O15014	ZNF609	P24941	CDK2	S433	V430F	430	Missense	distal	-3	no	13.262	13.306	EPSD	TCGA;ICGC;COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	O15014	ZNF609	P24941	CDK2	S433	R440Q	440	Missense	distal	7	no	13.262	12.618	EPSD	TCGA;ICGC;COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	O15014	ZNF609	P24941	CDK2	S491	P492L	492	Missense	proximal	1	no	12.135	2.314	EPSD	TCGA;ICGC;COSMIC	8.148	Loss
CMGC_CDK_CDK2_CDK2_ST	O15014	ZNF609	P24941	CDK2	S560	R563C	563	Missense	distal	3	no	16.246	9.882	EPSD	TCGA;ICGC;COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	O15014	ZNF609	P24941	CDK2	S560	R563H	563	Missense	distal	3	no	16.246	15.550	EPSD	TCGA;ICGC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	O15014	ZNF609	P24941	CDK2	T566	R563C	563	Missense	distal	-3	no	14.016	13.930	EPSD	TCGA;ICGC;COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	O15014	ZNF609	P24941	CDK2	T566	R570Q	570	Missense	distal	4	no	14.016	14.197	EPSD	TCGA;ICGC;COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	O15014	ZNF609	P24941	CDK2	T566	R563H	563	Missense	distal	-3	no	14.016	13.973	EPSD	TCGA;ICGC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	O15014	ZNF609	P24941	CDK2	S576	R570Q	570	Missense	distal	-6	no	15.211	15.212	EPSD	TCGA;ICGC;COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	O15014	ZNF609	P24941	CDK2	S576	S581N	581	Missense	distal	5	no	15.211	15.415	EPSD	TCGA;ICGC;COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	O15014	ZNF609	P24941	CDK2	S578	S581N	581	Missense	distal	3	no	13.590	12.993	EPSD	TCGA;ICGC;COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	O15014	ZNF609	P24941	CDK2	S609	G608C	608	Missense	proximal	-1	no	8.370	7.195	EPSD	TCGA;ICGC;COSMIC	8.148	Loss
CMGC_CDK_CDK2_CDK2_ST	O15014	ZNF609	P24941	CDK2	S609	D610H	610	Missense	proximal	1	no	8.370	9.856	EPSD	TCGA	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	O15014	ZNF609	P24941	CDK2	S680	S684Y	684	Missense	distal	4	no	12.267	12.453	EPSD	TCGA;ICGC;COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	O15014	ZNF609	P24941	CDK2	S680	G682D	682	Missense	proximal	2	no	12.267	12.147	EPSD	TCGA;ICGC;COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	O15014	ZNF609	P24941	CDK2	S698	A692T	692	Missense	distal	-6	no	14.022	14.023	EPSD	TCGA;ICGC;COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	O15014	ZNF609	P24941	CDK2	T722	K728E	728	Missense	distal	6	no	14.641	14.630	PhosphoSitePlus	TCGA;ICGC;COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	O15014	ZNF609	P24941	CDK2	S743	P744H	744	Missense	proximal	1	no	15.898	9.140	EPSD	TCGA;ICGC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	O15014	ZNF609	P24941	CDK2	S743	S743N	743	Missense	central	0	yes	15.898	0.000	EPSD	TCGA;ICGC	8.148	Loss
CMGC_CDK_CDK2_CDK2_ST	O15014	ZNF609	P24941	CDK2	T746	P744H	744	Missense	proximal	-2	no	17.951	16.941	EPSD	TCGA;ICGC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	O15014	ZNF609	P24941	CDK2	T746	S743N	743	Missense	distal	-3	no	17.951	17.877	EPSD	TCGA;ICGC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	O15014	ZNF609	P24941	CDK2	S758	E754Q	754	Missense	distal	-4	no	15.035	14.587	EPSD	TCGA;ICGC;COSMIC;CCLE	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	O15014	ZNF609	P24941	CDK2	T817	P824S	824	Missense	distal	7	no	10.966	10.814	EPSD	TCGA;ICGC;COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	O15014	ZNF609	P24941	CDK2	T823	P824S	824	Missense	proximal	1	no	16.245	4.979	EPSD	TCGA;ICGC;COSMIC	8.148	Loss
CMGC_CDK_CDK2_CDK2_ST	O15014	ZNF609	P24941	CDK2	S907	P913H	913	Missense	distal	6	no	11.560	11.555	EPSD	TCGA;ICGC;COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	O15014	ZNF609	P24941	CDK2	S907	A910V	910	Missense	distal	3	no	11.560	12.680	EPSD	TCGA;ICGC;COSMIC;GDSC;CCLE	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	O15014	ZNF609	P24941	CDK2	S1105	S1102G	1102	Missense	distal	-3	no	8.500	8.508	EPSD	TCGA;ICGC;COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	O15014	ZNF609	P24941	CDK2	S1216	S1216C	1216	Missense	central	0	yes	11.332	0.000	EPSD	TCGA	8.148	Loss
CMGC_CDK_CDK2_CDK2_ST	O15014	ZNF609	P24941	CDK2	S1285	A1284T	1284	Missense	proximal	-1	no	13.880	13.888	EPSD	TCGA;ICGC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	O15014	ZNF609	P24941	CDK2	S1313	K1310N	1310	Missense	distal	-3	no	13.990	14.051	EPSD	TCGA;ICGC;COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	O15014	ZNF609	P24941	CDK2	S1313	K1319N	1319	Missense	distal	6	no	13.990	13.985	EPSD	TCGA;ICGC;COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	O15014	ZNF609	P24941	CDK2	S1357	R1361C	1361	Missense	distal	4	no	12.275	11.648	EPSD	TCGA;ICGC;COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	O15014	ZNF609	P24941	CDK2	S1357	R1361H	1361	Missense	distal	4	no	12.275	12.158	EPSD	TCGA;ICGC;COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	P17706	PTPN2	P24941	CDK2	S52	R47G	47	Missense	distal	-5	no	12.359	12.392	EPSD	TCGA;ICGC;COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	P17706	PTPN2	P24941	CDK2	S52	R58C	58	Missense	distal	6	no	12.359	12.362	EPSD	TCGA;ICGC;COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	P17706	PTPN2	P24941	CDK2	T261	T261A	261	Missense	central	0	yes	11.726	0.000	EPSD	TCGA;ICGC;COSMIC	8.148	Loss
CMGC_CDK_CDK2_CDK2_ST	P17706	PTPN2	P24941	CDK2	T261	S268L	268	Missense	distal	7	no	11.726	11.908	EPSD	TCGA;ICGC;COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	P17706	PTPN2	P24941	CDK2	S298	S298C	298	Missense	central	0	yes	12.980	0.000	EPSD	TCGA;COSMIC	8.148	Loss
CMGC_CDK_CDK2_CDK2_ST	P17706	PTPN2	P24941	CDK2	S298	S298Y	298	Missense	central	0	yes	12.980	0.000	EPSD	TCGA;ICGC;COSMIC	8.148	Loss
CMGC_CDK_CDK2_CDK2_ST	P17706	PTPN2	P24941	CDK2	S298	P299S	299	Missense	proximal	1	no	12.980	1.714	EPSD	TCGA;ICGC;COSMIC	8.148	Loss
CMGC_CDK_CDK2_CDK2_ST	P17706	PTPN2	P24941	CDK2	S304	S298C	298	Missense	distal	-6	no	19.445	19.451	PhosphoSitePlus	TCGA;COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	P17706	PTPN2	P24941	CDK2	S304	S298Y	298	Missense	distal	-6	no	19.445	19.446	PhosphoSitePlus	TCGA;ICGC;COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	P17706	PTPN2	P24941	CDK2	S304	P299S	299	Missense	distal	-5	no	19.445	19.401	PhosphoSitePlus	TCGA;ICGC;COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	P17706	PTPN2	P24941	CDK2	T310	Y313H	313	Missense	distal	3	no	6.556	8.323	EPSD	TCGA;ICGC;COSMIC	8.148	Gain
CMGC_CDK_CDK2_CDK2_ST	Q9Y3Z3	SAMHD1	P24941	CDK2	S18	D17N	17	Missense	proximal	-1	no	13.904	13.074	EPSD	TCGA;ICGC;COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	Q9Y3Z3	SAMHD1	P24941	CDK2	S18	R20K	20	Missense	proximal	2	no	13.904	13.604	EPSD	TCGA;ICGC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	Q9Y3Z3	SAMHD1	P24941	CDK2	S18	R20I	20	Missense	proximal	2	no	13.904	13.722	EPSD	TCGA;ICGC;COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	Q9Y3Z3	SAMHD1	P24941	CDK2	T21	S27F	27	Missense	distal	6	no	14.942	14.923	EPSD	TCGA;ICGC;COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	Q9Y3Z3	SAMHD1	P24941	CDK2	T21	D17N	17	Missense	distal	-4	no	14.942	14.554	EPSD	TCGA;ICGC;COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	Q9Y3Z3	SAMHD1	P24941	CDK2	T21	R20K	20	Missense	proximal	-1	no	14.942	14.272	EPSD	TCGA;ICGC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	Q9Y3Z3	SAMHD1	P24941	CDK2	T21	R20I	20	Missense	proximal	-1	no	14.942	14.355	EPSD	TCGA;ICGC;COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	Q9Y3Z3	SAMHD1	P24941	CDK2	T25	S27F	27	Missense	proximal	2	no	13.338	13.522	EPSD	TCGA;ICGC;COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	Q9Y3Z3	SAMHD1	P24941	CDK2	T25	R20K	20	Missense	distal	-5	no	13.338	13.294	EPSD	TCGA;ICGC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	Q9Y3Z3	SAMHD1	P24941	CDK2	T25	R20I	20	Missense	distal	-5	no	13.338	13.330	EPSD	TCGA;ICGC;COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	Q9Y3Z3	SAMHD1	P24941	CDK2	S33	S27F	27	Missense	distal	-6	no	14.172	14.177	EPSD	TCGA;ICGC;COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	Q9Y3Z3	SAMHD1	P24941	CDK2	S33	E37A	37	Missense	distal	4	no	14.172	14.195	EPSD	TCGA;ICGC;COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	Q9Y3Z3	SAMHD1	P24941	CDK2	S33	H39Y	39	Missense	distal	6	no	14.172	14.169	EPSD	TCGA;ICGC;COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	Q9Y3Z3	SAMHD1	P24941	CDK2	T138	V133I	133	Missense	distal	-5	no	15.462	15.471	EPSD	TCGA;ICGC;COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	Q9Y3Z3	SAMHD1	P24941	CDK2	T138	D137N	137	Missense	proximal	-1	no	15.462	14.633	EPSD	TCGA;ICGC;COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	Q9Y3Z3	SAMHD1	P24941	CDK2	T138	I136F	136	Missense	proximal	-2	no	15.462	14.503	EPSD	TCGA;ICGC;COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	Q9Y3Z3	SAMHD1	P24941	CDK2	T138	D137H	137	Missense	proximal	-1	no	15.462	14.826	EPSD	TCGA;ICGC;COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	Q9Y3Z3	SAMHD1	P24941	CDK2	T138	R143C	143	Missense	distal	5	no	15.462	15.590	EPSD	TCGA;ICGC;COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	Q9Y3Z3	SAMHD1	P24941	CDK2	T434	S433C	433	Missense	proximal	-1	no	7.952	8.296	EPSD	TCGA	8.148	Gain
CMGC_CDK_CDK2_CDK2_ST	Q9Y3Z3	SAMHD1	P24941	CDK2	T592	P589T	589	Missense	distal	-3	no	17.916	17.876	PhosphoSitePlus	TCGA;ICGC;COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	Q9Y3Z3	SAMHD1	P24941	CDK2	T592	K596N	596	Missense	distal	4	no	17.916	17.494	PhosphoSitePlus	TCGA;ICGC;COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	Q9Y3Z3	SAMHD1	P24941	CDK2	T592	D585N	585	Missense	distal	-7	no	17.916	17.593	PhosphoSitePlus	TCGA;ICGC;COSMIC;GDSC;CCLE	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	O14497	ARID1A	P24941	CDK2	T377	P383S	383	Missense	distal	6	no	15.467	15.468	EPSD	TCGA;ICGC;COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	O14497	ARID1A	P24941	CDK2	S382	K389Q	389	Missense	distal	7	no	12.096	12.228	EPSD	TCGA;ICGC;COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	O14497	ARID1A	P24941	CDK2	S382	P383S	383	Missense	proximal	1	no	12.096	0.830	EPSD	TCGA;ICGC;COSMIC	8.148	Loss
CMGC_CDK_CDK2_CDK2_ST	O14497	ARID1A	P24941	CDK2	S658	E654K	654	Missense	distal	-4	no	15.491	15.179	EPSD	TCGA;ICGC;COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	O14497	ARID1A	P24941	CDK2	S658	G665A	665	Missense	distal	7	no	15.491	15.205	EPSD	TCGA;ICGC;COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	O14497	ARID1A	P24941	CDK2	S682	P680T	680	Missense	proximal	-2	no	11.289	11.255	EPSD	TCGA;ICGC;COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	O14497	ARID1A	P24941	CDK2	S682	P687H	687	Missense	distal	5	no	11.289	11.366	EPSD	TCGA;ICGC;COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	O14497	ARID1A	P24941	CDK2	S696	G701C	701	Missense	distal	5	no	13.124	13.231	EPSD	TCGA;ICGC;COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	O14497	ARID1A	P24941	CDK2	S696	I692N	692	Missense	distal	-4	no	13.124	13.413	EPSD	TCGA;ICGC;COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	O14497	ARID1A	P24941	CDK2	S698	G701C	701	Missense	distal	3	no	11.860	7.315	EPSD	TCGA;ICGC;COSMIC	8.148	Loss
CMGC_CDK_CDK2_CDK2_ST	O14497	ARID1A	P24941	CDK2	S698	I692N	692	Missense	distal	-6	no	11.860	11.857	EPSD	TCGA;ICGC;COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	O14497	ARID1A	P24941	CDK2	S702	G701C	701	Missense	proximal	-1	no	13.388	12.212	EPSD	TCGA;ICGC;COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	O14497	ARID1A	P24941	CDK2	S715	S715L	715	Missense	central	0	yes	14.829	0.000	EPSD	TCGA;ICGC;COSMIC	8.148	Loss
CMGC_CDK_CDK2_CDK2_ST	O14497	ARID1A	P24941	CDK2	S715	R710C	710	Missense	distal	-5	no	14.829	14.863	EPSD	TCGA;ICGC;COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	O14497	ARID1A	P24941	CDK2	S715	R710H	710	Missense	distal	-5	no	14.829	14.830	EPSD	TCGA;ICGC;COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	O14497	ARID1A	P24941	CDK2	S764	A770T	770	Missense	distal	6	no	14.114	14.126	EPSD	TCGA;ICGC;COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	O14497	ARID1A	P24941	CDK2	S764	M759V	759	Missense	distal	-5	no	14.114	14.038	EPSD	TCGA;ICGC;COSMIC;CCLE	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	O14497	ARID1A	P24941	CDK2	S772	R774H	774	Missense	proximal	2	no	13.634	13.553	EPSD	TCGA;ICGC;COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	O14497	ARID1A	P24941	CDK2	S772	G778R	778	Missense	distal	6	no	13.634	13.629	EPSD	TCGA;ICGC;COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	O14497	ARID1A	P24941	CDK2	S772	P776L	776	Missense	distal	4	no	13.634	13.746	EPSD	TCGA;ICGC;COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	O14497	ARID1A	P24941	CDK2	S772	A770T	770	Missense	proximal	-2	no	13.634	13.584	EPSD	TCGA;ICGC;COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	O14497	ARID1A	P24941	CDK2	S772	P773L	773	Missense	proximal	1	no	13.634	3.813	EPSD	TCGA;ICGC;COSMIC	8.148	Loss
CMGC_CDK_CDK2_CDK2_ST	O14497	ARID1A	P24941	CDK2	S777	R774H	774	Missense	distal	-3	no	8.248	8.205	EPSD	TCGA;ICGC;COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	O14497	ARID1A	P24941	CDK2	S777	G778R	778	Missense	proximal	1	no	8.248	5.761	EPSD	TCGA;ICGC;COSMIC	8.148	Loss
CMGC_CDK_CDK2_CDK2_ST	O14497	ARID1A	P24941	CDK2	S777	P776L	776	Missense	proximal	-1	no	8.248	8.068	EPSD	TCGA;ICGC;COSMIC	8.148	Loss
CMGC_CDK_CDK2_CDK2_ST	O14497	ARID1A	P24941	CDK2	S777	A770T	770	Missense	distal	-7	no	8.248	8.080	EPSD	TCGA;ICGC;COSMIC	8.148	Loss
CMGC_CDK_CDK2_CDK2_ST	O14497	ARID1A	P24941	CDK2	S777	P773L	773	Missense	distal	-4	no	8.248	8.189	EPSD	TCGA;ICGC;COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	O14497	ARID1A	P24941	CDK2	S964	G960V	960	Missense	distal	-4	no	14.072	14.342	EPSD	TCGA;ICGC;COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	O14497	ARID1A	P24941	CDK2	S964	N957T	957	Missense	distal	-7	no	14.072	14.151	EPSD	TCGA;ICGC;COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	O14497	ARID1A	P24941	CDK2	S1091	S1090I	1090	Missense	proximal	-1	no	8.131	8.584	EPSD	TCGA;ICGC;COSMIC	8.148	Gain
CMGC_CDK_CDK2_CDK2_ST	O14497	ARID1A	P24941	CDK2	S1126	S1123F	1123	Missense	distal	-3	no	10.976	11.067	EPSD	TCGA;ICGC;COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	O14497	ARID1A	P24941	CDK2	S1126	S1126F	1126	Missense	central	0	yes	10.976	0.000	EPSD	TCGA;ICGC;COSMIC	8.148	Loss
CMGC_CDK_CDK2_CDK2_ST	O14497	ARID1A	P24941	CDK2	S1138	P1144S	1144	Missense	distal	6	no	8.788	8.790	EPSD	TCGA;ICGC;COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	O14497	ARID1A	P24941	CDK2	T1146	P1144S	1144	Missense	proximal	-2	no	13.026	12.375	EPSD	TCGA;ICGC;COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	O14497	ARID1A	P24941	CDK2	T1206	Y1211C	1211	Missense	distal	5	no	16.056	16.216	EPSD	TCGA;ICGC;COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	O14497	ARID1A	P24941	CDK2	T1206	N1203Y	1203	Missense	distal	-3	no	16.056	16.150	EPSD	TCGA;ICGC;COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	O14497	ARID1A	P24941	CDK2	T1206	G1210V	1210	Missense	distal	4	no	16.056	16.403	EPSD	TCGA;ICGC;COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	O14497	ARID1A	P24941	CDK2	S1316	S1312Y	1312	Missense	distal	-4	no	8.789	8.900	EPSD	TCGA;ICGC;COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	O14497	ARID1A	P24941	CDK2	S1316	R1323L	1323	Missense	distal	7	no	8.789	8.330	EPSD	TCGA;ICGC;COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	O14497	ARID1A	P24941	CDK2	S1316	P1321S	1321	Missense	distal	5	no	8.789	8.688	EPSD	TCGA;ICGC;COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	O14497	ARID1A	P24941	CDK2	S1316	S1320Y	1320	Missense	distal	4	no	8.789	8.975	EPSD	TCGA;ICGC;COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	O14497	ARID1A	P24941	CDK2	S1316	L1309I	1309	Missense	distal	-7	no	8.789	8.978	EPSD	TCGA;ICGC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	O14497	ARID1A	P24941	CDK2	S1316	G1317W	1317	Missense	proximal	1	no	8.789	0.879	EPSD	TCGA;ICGC;COSMIC	8.148	Loss
CMGC_CDK_CDK2_CDK2_ST	O14497	ARID1A	P24941	CDK2	S1320	R1323L	1323	Missense	distal	3	no	15.061	12.959	EPSD	TCGA;ICGC;COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	O14497	ARID1A	P24941	CDK2	S1320	P1321S	1321	Missense	proximal	1	no	15.061	3.795	EPSD	TCGA;ICGC;COSMIC	8.148	Loss
CMGC_CDK_CDK2_CDK2_ST	O14497	ARID1A	P24941	CDK2	S1320	S1320Y	1320	Missense	central	0	yes	15.061	0.000	EPSD	TCGA;ICGC;COSMIC	8.148	Loss
CMGC_CDK_CDK2_CDK2_ST	O14497	ARID1A	P24941	CDK2	S1320	G1317W	1317	Missense	distal	-3	no	15.061	15.228	EPSD	TCGA;ICGC;COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	O14497	ARID1A	P24941	CDK2	T1348	T1345S	1345	Missense	distal	-3	no	15.419	15.554	EPSD	TCGA;ICGC;COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	O14497	ARID1A	P24941	CDK2	T1348	G1351D	1351	Missense	distal	3	no	15.419	13.706	EPSD	TCGA;ICGC;COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	O14497	ARID1A	P24941	CDK2	S1352	Q1357L	1357	Missense	distal	5	no	14.485	14.565	EPSD	TCGA;ICGC;COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	O14497	ARID1A	P24941	CDK2	S1352	T1345S	1345	Missense	distal	-7	no	14.485	14.308	EPSD	TCGA;ICGC;COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	O14497	ARID1A	P24941	CDK2	S1352	G1351D	1351	Missense	proximal	-1	no	14.485	14.192	EPSD	TCGA;ICGC;COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	O14497	ARID1A	P24941	CDK2	S1587	P1583S	1583	Missense	distal	-4	no	12.253	12.607	EPSD	TCGA;COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	O14497	ARID1A	P24941	CDK2	S1600	S1600F	1600	Missense	central	0	yes	16.177	0.000	EPSD	TCGA;COSMIC	8.148	Loss
CMGC_CDK_CDK2_CDK2_ST	O14497	ARID1A	P24941	CDK2	S1600	P1605S	1605	Missense	distal	5	no	16.177	16.076	EPSD	TCGA;COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	O14497	ARID1A	P24941	CDK2	S1604	S1600F	1600	Missense	distal	-4	no	11.803	10.841	EPSD	TCGA;COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	O14497	ARID1A	P24941	CDK2	S1604	P1605S	1605	Missense	proximal	1	no	11.803	0.537	EPSD	TCGA;COSMIC	8.148	Loss
CMGC_CDK_CDK2_CDK2_ST	O14497	ARID1A	P24941	CDK2	S1609	P1605S	1605	Missense	distal	-4	no	10.801	11.155	EPSD	TCGA;COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	O14497	ARID1A	P24941	CDK2	S1609	A1616T	1616	Missense	distal	7	no	10.801	10.112	EPSD	TCGA;COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	O14497	ARID1A	P24941	CDK2	T1666	M1661I	1661	Missense	distal	-5	no	14.957	14.890	EPSD	TCGA;COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	O14497	ARID1A	P24941	CDK2	S1755	A1757P	1757	Missense	proximal	2	no	14.401	14.376	EPSD	TCGA;COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	O14497	ARID1A	P24941	CDK2	S1755	A1757S	1757	Missense	proximal	2	no	14.401	14.443	EPSD	TCGA	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	O14497	ARID1A	P24941	CDK2	S1755	P1756R	1756	Missense	proximal	1	no	14.401	4.602	EPSD	TCGA;COSMIC	8.148	Loss
CMGC_CDK_CDK2_CDK2_ST	O14497	ARID1A	P24941	CDK2	S1944	P1945L	1945	Missense	proximal	1	no	14.606	4.785	EPSD	TCGA;COSMIC	8.148	Loss
CMGC_CDK_CDK2_CDK2_ST	O14497	ARID1A	P24941	CDK2	S1944	Q1947H	1947	Missense	distal	3	no	14.606	15.653	EPSD	TCGA;COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	O14497	ARID1A	P24941	CDK2	S1948	P1945L	1945	Missense	distal	-3	no	8.153	8.082	EPSD	TCGA;COSMIC	8.148	Loss
CMGC_CDK_CDK2_CDK2_ST	O14497	ARID1A	P24941	CDK2	S1948	Q1947H	1947	Missense	proximal	-1	no	8.153	8.580	EPSD	TCGA;COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	O14497	ARID1A	P24941	CDK2	S2113	P2114L	2114	Missense	proximal	1	no	13.433	3.612	EPSD	TCGA;COSMIC	8.148	Loss
CMGC_CDK_CDK2_CDK2_ST	O14497	ARID1A	P24941	CDK2	S2113	A2110D	2110	Missense	distal	-3	no	13.433	13.557	EPSD	TCGA	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	O14497	ARID1A	P24941	CDK2	S2113	A2110V	2110	Missense	distal	-3	no	13.433	13.635	EPSD	TCGA	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	O14497	ARID1A	P24941	CDK2	S2113	P2114Q	2114	Missense	proximal	1	no	13.433	5.522	EPSD	TCGA	8.148	Loss
CMGC_CDK_CDK2_CDK2_ST	Q7KZ85	SUPT6H	P24941	CDK2	S75	S78L	78	Missense	distal	3	no	8.965	8.548	EPSD	TCGA;ICGC;COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	Q7KZ85	SUPT6H	P24941	CDK2	S75	E71K	71	Missense	distal	-4	no	8.965	8.654	EPSD	TCGA;ICGC;COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	Q7KZ85	SUPT6H	P24941	CDK2	S75	D81N	81	Missense	distal	6	no	8.965	8.984	EPSD	TCGA;ICGC;COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	Q7KZ85	SUPT6H	P24941	CDK2	S75	S75Y	75	Missense	central	0	yes	8.965	0.000	EPSD	TCGA;ICGC;COSMIC	8.148	Loss
CMGC_CDK_CDK2_CDK2_ST	Q7KZ85	SUPT6H	P24941	CDK2	S125	E128K	128	Missense	distal	3	no	6.772	8.858	EPSD	TCGA	8.148	Gain
CMGC_CDK_CDK2_CDK2_ST	Q7KZ85	SUPT6H	P24941	CDK2	T327	P328A	328	Missense	proximal	1	no	14.344	-0.059	EPSD	TCGA;ICGC;COSMIC	8.148	Loss
CMGC_CDK_CDK2_CDK2_ST	Q7KZ85	SUPT6H	P24941	CDK2	T327	A326P	326	Missense	proximal	-1	no	14.344	14.615	EPSD	TCGA	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	Q7KZ85	SUPT6H	P24941	CDK2	T327	R322W	322	Missense	distal	-5	no	14.344	14.432	EPSD	TCGA;ICGC;COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	Q7KZ85	SUPT6H	P24941	CDK2	T619	K626E	626	Missense	distal	7	no	12.869	13.200	EPSD	TCGA;ICGC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	Q7KZ85	SUPT6H	P24941	CDK2	T619	R613T	613	Missense	distal	-6	no	12.869	12.867	EPSD	TCGA;ICGC;COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	Q7KZ85	SUPT6H	P24941	CDK2	T619	P620L	620	Missense	proximal	1	no	12.869	3.048	EPSD	TCGA;ICGC;COSMIC;CCLE	8.148	Loss
CMGC_CDK_CDK2_CDK2_ST	Q7KZ85	SUPT6H	P24941	CDK2	T619	K623I	623	Missense	distal	4	no	12.869	12.439	EPSD	TCGA;ICGC;COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	Q7KZ85	SUPT6H	P24941	CDK2	T619	K622R	622	Missense	distal	3	no	12.869	11.880	EPSD	TCGA;ICGC;COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	Q7KZ85	SUPT6H	P24941	CDK2	T835	F839L	839	Missense	distal	4	no	7.973	8.268	EPSD	TCGA;ICGC;COSMIC	8.148	Gain
CMGC_CDK_CDK2_CDK2_ST	Q7KZ85	SUPT6H	P24941	CDK2	T1614	P1611S	1611	Missense	distal	-3	no	11.362	11.457	EPSD	TCGA;ICGC;COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	Q7KZ85	SUPT6H	P24941	CDK2	T1618	P1611S	1611	Missense	distal	-7	no	12.531	12.352	EPSD	TCGA;ICGC;COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	Q7KZ85	SUPT6H	P24941	CDK2	T1618	S1622F	1622	Missense	distal	4	no	12.531	12.336	EPSD	TCGA;ICGC;COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	Q7KZ85	SUPT6H	P24941	CDK2	T1618	T1624M	1624	Missense	distal	6	no	12.531	12.505	EPSD	TCGA;ICGC;COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	Q7KZ85	SUPT6H	P24941	CDK2	S1668	A1670G	1670	Missense	proximal	2	no	8.551	8.644	EPSD	TCGA;ICGC;COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	Q7KZ85	SUPT6H	P24941	CDK2	S1668	K1665R	1665	Missense	distal	-3	no	8.551	8.781	EPSD	TCGA;ICGC;COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	Q7KZ85	SUPT6H	P24941	CDK2	S1668	G1675R	1675	Missense	distal	7	no	8.551	8.371	EPSD	TCGA;ICGC;COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	Q7KZ85	SUPT6H	P24941	CDK2	T1697	P1698H	1698	Missense	proximal	1	no	12.430	5.672	EPSD	TCGA;ICGC	8.148	Loss
CMGC_CDK_CDK2_CDK2_ST	Q7KZ85	SUPT6H	P24941	CDK2	S1701	P1698H	1698	Missense	distal	-3	no	14.762	14.908	EPSD	TCGA;ICGC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	Q7KZ85	SUPT6H	P24941	CDK2	S1703	P1710S	1710	Missense	distal	7	no	12.593	12.441	EPSD	TCGA;ICGC;COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	Q7KZ85	SUPT6H	P24941	CDK2	S1703	P1698H	1698	Missense	distal	-5	no	12.593	12.640	EPSD	TCGA;ICGC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	Q7KZ85	SUPT6H	P24941	CDK2	T1709	S1712C	1712	Missense	distal	3	no	14.085	9.405	EPSD	TCGA;ICGC;COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	Q7KZ85	SUPT6H	P24941	CDK2	T1709	P1710S	1710	Missense	proximal	1	no	14.085	2.819	EPSD	TCGA;ICGC;COSMIC	8.148	Loss
CMGC_CDK_CDK2_CDK2_ST	Q7KZ85	SUPT6H	P24941	CDK2	T1718	S1712C	1712	Missense	distal	-6	no	13.489	13.495	EPSD	TCGA;ICGC;COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	Q7KZ85	SUPT6H	P24941	CDK2	T1718	E1723K	1723	Missense	distal	5	no	13.489	13.356	EPSD	TCGA;ICGC;COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	Q7KZ85	SUPT6H	P24941	CDK2	T1718	L1721M	1721	Missense	distal	3	no	13.489	13.633	EPSD	TCGA;ICGC;COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	Q12948	FOXC1	P24941	CDK2	T68	A63T	63	Missense	distal	-5	no	16.913	16.887	PhosphoSitePlus	TCGA;ICGC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	Q12948	FOXC1	P24941	CDK2	T68	D75N	75	Missense	distal	7	no	16.913	16.133	PhosphoSitePlus	TCGA;ICGC;COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	Q12948	FOXC1	P24941	CDK2	S521	G517D	517	Missense	distal	-4	no	8.496	9.341	EPSD	TCGA;ICGC;COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	Q12948	FOXC1	P24941	CDK2	S521	S521F	521	Missense	central	0	yes	8.496	0.000	EPSD	TCGA;ICGC;COSMIC	8.148	Loss
CMGC_CDK_CDK2_CDK2_ST	Q12948	FOXC1	P24941	CDK2	S521	S527I	527	Missense	distal	6	no	8.496	8.495	EPSD	TCGA;ICGC;COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	Q6UB35	MTHFD1L	P24941	CDK2	S357	L356F	356	Missense	proximal	-1	no	14.360	15.326	PhosphoSitePlus	TCGA;ICGC;COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	Q6UB35	MTHFD1L	P24941	CDK2	S357	D362N	362	Missense	distal	5	no	14.360	14.290	PhosphoSitePlus	TCGA;ICGC;COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	Q6UB35	MTHFD1L	P24941	CDK2	S357	S357C	357	Missense	central	0	yes	14.360	0.000	PhosphoSitePlus	TCGA;ICGC;COSMIC	8.148	Loss
CMGC_CDK_CDK2_CDK2_ST	Q6UB35	MTHFD1L	P24941	CDK2	S357	D362Y	362	Missense	distal	5	no	14.360	14.260	PhosphoSitePlus	TCGA;ICGC;COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	Q6UB35	MTHFD1L	P24941	CDK2	S639	D637V	637	Missense	proximal	-2	no	9.570	9.055	EPSD	TCGA	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	Q6UB35	MTHFD1L	P24941	CDK2	S639	K638E	638	Missense	proximal	-1	no	9.570	10.456	EPSD	TCGA;ICGC;COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	Q6UB35	MTHFD1L	P24941	CDK2	S885	P886L	886	Missense	proximal	1	no	14.109	4.288	EPSD	TCGA;ICGC;COSMIC	8.148	Loss
CMGC_CDK_CDK2_CDK2_ST	Q15047	SETDB1	P24941	CDK2	T144	R151C	151	Missense	distal	7	no	11.022	11.173	EPSD	TCGA;ICGC;COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	Q15047	SETDB1	P24941	CDK2	T443	G440D	440	Missense	distal	-3	no	9.880	9.841	EPSD	TCGA;ICGC;COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	Q15047	SETDB1	P24941	CDK2	S468	P466S	466	Missense	proximal	-2	no	13.337	12.686	EPSD	TCGA;ICGC;COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	Q15047	SETDB1	P24941	CDK2	S468	S468F	468	Missense	central	0	yes	13.337	0.000	EPSD	TCGA;ICGC;COSMIC	8.148	Loss
CMGC_CDK_CDK2_CDK2_ST	Q15047	SETDB1	P24941	CDK2	S505	S501F	501	Missense	distal	-4	no	12.742	11.780	EPSD	TCGA;ICGC;COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	Q15047	SETDB1	P24941	CDK2	S505	S498Y	498	Missense	distal	-7	no	12.742	13.048	EPSD	TCGA;ICGC;COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	Q15047	SETDB1	P24941	CDK2	S508	S501F	501	Missense	distal	-7	no	13.979	14.530	EPSD	TCGA;ICGC;COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	Q15047	SETDB1	P24941	CDK2	S528	R527S	527	Missense	proximal	-1	no	12.702	11.660	EPSD	TCGA;ICGC;COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	Q15047	SETDB1	P24941	CDK2	S528	Y526H	526	Missense	proximal	-2	no	12.702	12.256	EPSD	TCGA;ICGC;COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	Q15047	SETDB1	P24941	CDK2	S528	S528L	528	Missense	central	0	yes	12.702	0.000	EPSD	TCGA;ICGC;COSMIC	8.148	Loss
CMGC_CDK_CDK2_CDK2_ST	Q15047	SETDB1	P24941	CDK2	S528	Y526C	526	Missense	proximal	-2	no	12.702	12.204	EPSD	TCGA	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	Q15047	SETDB1	P24941	CDK2	T700	E696Q	696	Missense	distal	-4	no	14.090	13.641	EPSD	TCGA;ICGC;COSMIC;CCLE	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	Q15047	SETDB1	P24941	CDK2	T700	E696K	696	Missense	distal	-4	no	14.090	13.778	EPSD	TCGA;ICGC;COSMIC;GDSC;CCLE	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	Q15047	SETDB1	P24941	CDK2	T700	C693R	693	Missense	distal	-7	no	14.090	14.162	EPSD	TCGA;ICGC;COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	Q15047	SETDB1	P24941	CDK2	T700	P703L	703	Missense	distal	3	no	14.090	13.706	EPSD	TCGA;ICGC;COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	Q15047	SETDB1	P24941	CDK2	S906	S905R	905	Missense	proximal	-1	no	8.602	9.644	EPSD	TCGA;ICGC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	Q15047	SETDB1	P24941	CDK2	T976	E975Q	975	Missense	proximal	-1	no	11.996	10.903	EPSD	TCGA;ICGC;COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	Q15047	SETDB1	P24941	CDK2	T976	A982T	982	Missense	distal	6	no	11.996	12.008	EPSD	TCGA;ICGC;COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	Q15047	SETDB1	P24941	CDK2	S1066	R1059G	1059	Missense	distal	-7	no	16.411	16.391	PhosphoSitePlus	TCGA;ICGC;COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	Q15047	SETDB1	P24941	CDK2	S1066	R1059Q	1059	Missense	distal	-7	no	16.411	16.024	PhosphoSitePlus	TCGA;ICGC;COSMIC;CCLE	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	Q15047	SETDB1	P24941	CDK2	T1197	R1198H	1198	Missense	proximal	1	no	5.160	8.200	EPSD	TCGA;ICGC;COSMIC	8.148	Gain
CMGC_CDK_CDK2_CDK2_ST	O60934	NBN	P24941	CDK2	T337	P338L	338	Missense	proximal	1	no	14.306	4.485	EPSD	TCGA;COSMIC	8.148	Loss
CMGC_CDK_CDK2_CDK2_ST	O60934	NBN	P24941	CDK2	T337	T337N	337	Missense	central	0	yes	14.306	0.000	EPSD	TCGA;COSMIC	8.148	Loss
CMGC_CDK_CDK2_CDK2_ST	O60934	NBN	P24941	CDK2	T337	T337I	337	Missense	central	0	yes	14.306	0.000	EPSD	TCGA;COSMIC	8.148	Loss
CMGC_CDK_CDK2_CDK2_ST	O60934	NBN	P24941	CDK2	S432	Q430R	430	Missense	proximal	-2	no	16.721	16.052	PhosphoSitePlus	TCGA;COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	O60934	NBN	P24941	CDK2	S432	P433S	433	Missense	proximal	1	no	16.721	5.455	PhosphoSitePlus	TCGA	8.148	Loss
CMGC_CDK_CDK2_CDK2_ST	O60934	NBN	P24941	CDK2	S462	K464E	464	Missense	proximal	2	no	8.501	8.739	EPSD	TCGA;ICGC;COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	O60934	NBN	P24941	CDK2	T497	S499L	499	Missense	proximal	2	no	11.773	11.599	EPSD	TCGA;COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	O60934	NBN	P24941	CDK2	S499	S499L	499	Missense	central	0	yes	10.030	0.000	EPSD	TCGA;COSMIC	8.148	Loss
CMGC_CDK_CDK2_CDK2_ST	Q6PKG0	LARP1	P24941	CDK2	S631	E630D	630	Missense	proximal	-1	no	8.187	8.158	EPSD	TCGA;ICGC;COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	Q8NBZ0	INO80E	P24941	CDK2	T90	P91Q	91	Missense	proximal	1	no	13.621	5.709	EPSD	TCGA;ICGC;COSMIC	8.148	Loss
CMGC_CDK_CDK2_CDK2_ST	Q8NBZ0	INO80E	P24941	CDK2	S98	P91Q	91	Missense	distal	-7	no	12.680	12.637	EPSD	TCGA;ICGC;COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	Q8NBZ0	INO80E	P24941	CDK2	S106	P107L	107	Missense	proximal	1	no	10.328	0.507	EPSD	TCGA;ICGC;COSMIC;GDSC;CCLE	8.148	Loss
CMGC_CDK_CDK2_CDK2_ST	Q8NBZ0	INO80E	P24941	CDK2	S127	S123F	123	Missense	distal	-4	no	12.327	11.365	EPSD	TCGA;ICGC;COSMIC;GDSC;CCLE	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	Q8NBZ0	INO80E	P24941	CDK2	S127	P126L	126	Missense	proximal	-1	no	12.327	12.147	EPSD	TCGA;ICGC;COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	Q8NBZ0	INO80E	P24941	CDK2	S154	R160W	160	Missense	distal	6	no	14.442	14.434	PhosphoSitePlus	TCGA;ICGC;COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	Q8NBZ0	INO80E	P24941	CDK2	S154	E161K	161	Missense	distal	7	no	14.442	14.111	PhosphoSitePlus	TCGA;ICGC;COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	Q8NBZ0	INO80E	P24941	CDK2	S154	R157G	157	Missense	distal	3	no	14.442	12.623	PhosphoSitePlus	TCGA;ICGC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	Q8NBZ0	INO80E	P24941	CDK2	T201	K207N	207	Missense	distal	6	no	14.793	14.789	EPSD	TCGA;ICGC;COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	Q9UPN3	MACF1	P24941	CDK2	S35	R30W	30	Missense	distal	-5	no	15.290	15.377	EPSD	TCGA;ICGC;COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	Q9UPN3	MACF1	P24941	CDK2	S35	P36S	36	Missense	proximal	1	no	15.290	4.024	EPSD	TCGA;ICGC;COSMIC	8.148	Loss
CMGC_CDK_CDK2_CDK2_ST	Q9UPN3	MACF1	P24941	CDK2	S35	E29K	29	Missense	distal	-6	no	15.290	15.287	EPSD	TCGA;ICGC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	Q9UPN3	MACF1	P24941	CDK2	T212	G213A	213	Missense	proximal	1	no	10.890	3.799	EPSD	TCGA;ICGC;COSMIC	8.148	Loss
CMGC_CDK_CDK2_CDK2_ST	Q9UPN3	MACF1	P24941	CDK2	S280	I287V	287	Missense	distal	7	no	15.487	15.688	EPSD	TCGA;ICGC;COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	Q9UPN3	MACF1	P24941	CDK2	S280	D275H	275	Missense	distal	-5	no	15.487	15.476	EPSD	TCGA;ICGC;COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	Q9UPN3	MACF1	P24941	CDK2	S862	R861C	861	Missense	proximal	-1	no	15.065	14.368	EPSD	TCGA;ICGC;COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	Q9UPN3	MACF1	P24941	CDK2	S862	V856I	856	Missense	distal	-6	no	15.065	15.066	EPSD	TCGA;ICGC;COSMIC;GDSC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	Q9UPN3	MACF1	P24941	CDK2	S898	S898F	898	Missense	central	0	yes	8.562	0.000	EPSD	TCGA;ICGC;COSMIC	8.148	Loss
CMGC_CDK_CDK2_CDK2_ST	Q9UPN3	MACF1	P24941	CDK2	S898	L894I	894	Missense	distal	-4	no	8.562	8.470	EPSD	TCGA;ICGC;COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	Q9UPN3	MACF1	P24941	CDK2	S1122	S1127I	1127	Missense	distal	5	no	12.918	13.112	EPSD	TCGA;ICGC;COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	Q9UPN3	MACF1	P24941	CDK2	S1122	S1124C	1124	Missense	proximal	2	no	12.918	12.997	EPSD	TCGA;ICGC;COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	Q9UPN3	MACF1	P24941	CDK2	S1122	P1123L	1123	Missense	proximal	1	no	12.918	3.097	EPSD	TCGA;ICGC;COSMIC	8.148	Loss
CMGC_CDK_CDK2_CDK2_ST	Q9UPN3	MACF1	P24941	CDK2	S1363	P1368S	1368	Missense	distal	5	no	9.734	9.634	EPSD	TCGA;ICGC;COSMIC;CCLE	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	Q9UPN3	MACF1	P24941	CDK2	S1363	S1363L	1363	Missense	central	0	yes	9.734	0.000	EPSD	TCGA;ICGC;COSMIC	8.148	Loss
CMGC_CDK_CDK2_CDK2_ST	Q9UPN3	MACF1	P24941	CDK2	S1363	S1367F	1367	Missense	distal	4	no	9.734	9.539	EPSD	TCGA;ICGC;COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	Q9UPN3	MACF1	P24941	CDK2	S1367	P1368S	1368	Missense	proximal	1	no	16.855	5.589	EPSD	TCGA;ICGC;COSMIC;CCLE	8.148	Loss
CMGC_CDK_CDK2_CDK2_ST	Q9UPN3	MACF1	P24941	CDK2	S1367	S1363L	1363	Missense	distal	-4	no	16.855	16.442	EPSD	TCGA;ICGC;COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	Q9UPN3	MACF1	P24941	CDK2	S1367	S1367F	1367	Missense	central	0	yes	16.855	0.000	EPSD	TCGA;ICGC;COSMIC	8.148	Loss
CMGC_CDK_CDK2_CDK2_ST	Q03252	LMNB2	P24941	CDK2	S90	I92V	92	Missense	proximal	2	no	10.082	10.227	EPSD	TCGA;ICGC;COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	Q03252	LMNB2	P24941	CDK2	S405	E400Q	400	Missense	distal	-5	no	11.285	11.248	EPSD	TCGA;COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	Q03252	LMNB2	P24941	CDK2	S405	E400D	400	Missense	distal	-5	no	11.285	11.305	EPSD	TCGA	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	Q03252	LMNB2	P24941	CDK2	S407	E400Q	400	Missense	distal	-7	no	13.039	12.906	EPSD	TCGA;COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	Q03252	LMNB2	P24941	CDK2	S407	E400D	400	Missense	distal	-7	no	13.039	13.190	EPSD	TCGA	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	Q03252	LMNB2	P24941	CDK2	S407	V414I	414	Missense	distal	7	no	13.039	12.837	EPSD	TCGA;COSMIC;CCLE	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	Q03252	LMNB2	P24941	CDK2	T518	E512D	512	Missense	distal	-6	no	11.843	11.839	EPSD	TCGA;COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	Q03252	LMNB2	P24941	CDK2	T518	I513F	513	Missense	distal	-5	no	11.843	11.876	EPSD	TCGA;COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	Q03252	LMNB2	P24941	CDK2	T518	Y521C	521	Missense	distal	3	no	11.843	7.943	EPSD	TCGA;COSMIC	8.148	Loss
CMGC_CDK_CDK2_CDK2_ST	Q03252	LMNB2	P24941	CDK2	T518	A514T	514	Missense	distal	-4	no	11.843	12.068	EPSD	TCGA;COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	Q03252	LMNB2	P24941	CDK2	S541	T545M	545	Missense	distal	4	no	15.989	15.285	EPSD	TCGA;COSMIC;CCLE	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	P33993	MCM7	P24941	CDK2	S121	P122R	122	Missense	proximal	1	no	14.179	4.381	PhosphoSitePlus;EPSD	TCGA;ICGC;COSMIC	8.148	Loss
CMGC_CDK_CDK2_CDK2_ST	P33993	MCM7	P24941	CDK2	S121	A128T	128	Missense	distal	7	no	14.179	13.491	PhosphoSitePlus;EPSD	TCGA;ICGC;COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	P33993	MCM7	P24941	CDK2	S121	Q123H	123	Missense	proximal	2	no	14.179	14.198	PhosphoSitePlus;EPSD	TCGA;ICGC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	P33993	MCM7	P24941	CDK2	S121	R114W	114	Missense	distal	-7	no	14.179	14.350	PhosphoSitePlus;EPSD	TCGA;COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	P33993	MCM7	P24941	CDK2	S365	G360R	360	Missense	distal	-5	no	15.149	15.116	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	P33993	MCM7	P24941	CDK2	S365	V359F	359	Missense	distal	-6	no	15.149	15.151	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	Q9UIF9	BAZ2A	P24941	CDK2	S21	S28F	28	Missense	distal	7	no	8.645	9.499	EPSD	TCGA;ICGC;COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	Q9UIF9	BAZ2A	P24941	CDK2	S26	S28F	28	Missense	proximal	2	no	14.162	14.346	EPSD	TCGA;ICGC;COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	Q9UIF9	BAZ2A	P24941	CDK2	S29	S28F	28	Missense	proximal	-1	no	7.872	9.128	EPSD	TCGA;ICGC;COSMIC	8.148	Gain
CMGC_CDK_CDK2_CDK2_ST	Q9UIF9	BAZ2A	P24941	CDK2	S38	G37R	37	Missense	proximal	-1	no	14.496	14.018	EPSD	TCGA;ICGC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	Q9UIF9	BAZ2A	P24941	CDK2	S135	H138R	138	Missense	distal	3	no	13.535	14.231	EPSD	TCGA	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	Q9UIF9	BAZ2A	P24941	CDK2	S156	S156R	156	Missense	central	0	yes	15.908	0.000	EPSD	TCGA;ICGC;COSMIC	8.148	Loss
CMGC_CDK_CDK2_CDK2_ST	Q9UIF9	BAZ2A	P24941	CDK2	S156	S156N	156	Missense	central	0	yes	15.908	0.000	EPSD	TCGA;ICGC	8.148	Loss
CMGC_CDK_CDK2_CDK2_ST	Q9UIF9	BAZ2A	P24941	CDK2	S492	K494E	494	Missense	proximal	2	no	11.721	11.959	EPSD	TCGA;ICGC;COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	Q9UIF9	BAZ2A	P24941	CDK2	S492	S496F	496	Missense	distal	4	no	11.721	11.526	EPSD	TCGA;ICGC;COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	Q9UIF9	BAZ2A	P24941	CDK2	S492	T491I	491	Missense	proximal	-1	no	11.721	11.968	EPSD	TCGA;ICGC;COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	Q9UIF9	BAZ2A	P24941	CDK2	S496	K494E	494	Missense	proximal	-2	no	13.083	12.482	EPSD	TCGA;ICGC;COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	Q9UIF9	BAZ2A	P24941	CDK2	S496	S496F	496	Missense	central	0	yes	13.083	0.000	EPSD	TCGA;ICGC;COSMIC	8.148	Loss
CMGC_CDK_CDK2_CDK2_ST	Q9UIF9	BAZ2A	P24941	CDK2	S496	T491I	491	Missense	distal	-5	no	13.083	13.123	EPSD	TCGA;ICGC;COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	Q9UIF9	BAZ2A	P24941	CDK2	S500	K494E	494	Missense	distal	-6	no	11.090	11.093	EPSD	TCGA;ICGC;COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	Q9UIF9	BAZ2A	P24941	CDK2	S500	S496F	496	Missense	distal	-4	no	11.090	10.128	EPSD	TCGA;ICGC;COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	Q9UIF9	BAZ2A	P24941	CDK2	T548	E551K	551	Missense	distal	3	no	13.987	16.073	EPSD	TCGA;ICGC;COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	Q9UIF9	BAZ2A	P24941	CDK2	T548	R553C	553	Missense	distal	5	no	13.987	14.115	EPSD	TCGA;ICGC;COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	Q9UIF9	BAZ2A	P24941	CDK2	T548	L554H	554	Missense	distal	6	no	13.987	13.981	EPSD	TCGA;ICGC;COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	Q9UIF9	BAZ2A	P24941	CDK2	T548	L554I	554	Missense	distal	6	no	13.987	13.986	EPSD	TCGA;ICGC;COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	Q9UIF9	BAZ2A	P24941	CDK2	S613	P614S	614	Missense	proximal	1	no	15.705	4.440	EPSD	TCGA;ICGC;COSMIC	8.148	Loss
CMGC_CDK_CDK2_CDK2_ST	Q9UIF9	BAZ2A	P24941	CDK2	S613	R615H	615	Missense	proximal	2	no	15.705	15.624	EPSD	TCGA;ICGC;COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	Q9UIF9	BAZ2A	P24941	CDK2	T995	L996P	996	Missense	proximal	1	no	1.007	10.828	EPSD	TCGA;ICGC;COSMIC	8.148	Gain
CMGC_CDK_CDK2_CDK2_ST	Q9UIF9	BAZ2A	P24941	CDK2	S1370	F1374L	1374	Missense	distal	4	no	12.068	12.362	EPSD	TCGA;ICGC;COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	Q9UIF9	BAZ2A	P24941	CDK2	S1370	T1377M	1377	Missense	distal	7	no	12.068	12.917	EPSD	TCGA;ICGC;COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	Q9UIF9	BAZ2A	P24941	CDK2	T1377	F1374L	1374	Missense	distal	-3	no	13.296	13.038	EPSD	TCGA;ICGC;COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	Q9UIF9	BAZ2A	P24941	CDK2	T1377	T1377M	1377	Missense	central	0	yes	13.296	0.000	EPSD	TCGA;ICGC;COSMIC	8.148	Loss
CMGC_CDK_CDK2_CDK2_ST	Q9UIF9	BAZ2A	P24941	CDK2	T1377	P1378S	1378	Missense	proximal	1	no	13.296	2.030	EPSD	TCGA	8.148	Loss
CMGC_CDK_CDK2_CDK2_ST	Q9UIF9	BAZ2A	P24941	CDK2	S1397	P1398L	1398	Missense	proximal	1	no	14.426	4.605	EPSD	TCGA;COSMIC	8.148	Loss
CMGC_CDK_CDK2_CDK2_ST	Q9UIF9	BAZ2A	P24941	CDK2	S1542	P1543L	1543	Missense	proximal	1	no	13.507	3.686	EPSD	TCGA	8.148	Loss
CMGC_CDK_CDK2_CDK2_ST	Q9UIF9	BAZ2A	P24941	CDK2	S1545	P1543L	1543	Missense	proximal	-2	no	9.024	8.800	EPSD	TCGA	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	Q9UIF9	BAZ2A	P24941	CDK2	S1545	L1550V	1550	Missense	distal	5	no	9.024	8.951	EPSD	TCGA;ICGC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	Q9UIF9	BAZ2A	P24941	CDK2	T1621	E1627K	1627	Missense	distal	6	no	12.990	13.001	EPSD	TCGA;ICGC;COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	Q9UIF9	BAZ2A	P24941	CDK2	S1783	P1784L	1784	Missense	proximal	1	no	17.831	8.010	EPSD	TCGA;ICGC;COSMIC	8.148	Loss
CMGC_CDK_CDK2_CDK2_ST	Q9UIF9	BAZ2A	P24941	CDK2	S1783	R1788W	1788	Missense	distal	5	no	17.831	17.998	EPSD	TCGA;ICGC;COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	P22234	PAICS	P24941	CDK2	S27	E23K	23	Missense	distal	-4	no	18.378	18.066	PhosphoSitePlus	TCGA;ICGC;CCLE	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	Q6Y7W6	GIGYF2	P24941	CDK2	T85	R90I	90	Missense	distal	5	no	8.581	8.567	EPSD	TCGA;ICGC;COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	Q6Y7W6	GIGYF2	P24941	CDK2	T85	P78Q	78	Missense	distal	-7	no	8.581	8.538	EPSD	TCGA;ICGC;COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	Q6Y7W6	GIGYF2	P24941	CDK2	S158	S158L	158	Missense	central	0	yes	8.312	0.000	EPSD	TCGA;ICGC;COSMIC	8.148	Loss
CMGC_CDK_CDK2_CDK2_ST	Q6Y7W6	GIGYF2	P24941	CDK2	S273	D280H	280	Missense	distal	7	no	10.054	9.499	EPSD	TCGA;ICGC;COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	Q6Y7W6	GIGYF2	P24941	CDK2	S275	D280H	280	Missense	distal	5	no	9.577	9.481	EPSD	TCGA;ICGC;COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	Q9NXR1	NDE1	P24941	CDK2	T191	P192H	192	Missense	proximal	1	no	12.949	6.190	EPSD	TCGA;ICGC;COSMIC	8.148	Loss
CMGC_CDK_CDK2_CDK2_ST	Q9NXR1	NDE1	P24941	CDK2	T215	S211F	211	Missense	distal	-4	no	13.557	12.595	EPSD	TCGA;ICGC;COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	Q9NXR1	NDE1	P24941	CDK2	T228	S224L	224	Missense	distal	-4	no	14.584	14.171	PhosphoSitePlus	TCGA;ICGC;COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	Q9NXR1	NDE1	P24941	CDK2	T228	S223G	223	Missense	distal	-5	no	14.584	14.708	PhosphoSitePlus	TCGA;ICGC;COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	Q9NXR1	NDE1	P24941	CDK2	T243	R250W	250	Missense	distal	7	no	14.404	14.803	EPSD	TCGA;ICGC;COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	Q9NXR1	NDE1	P24941	CDK2	T243	T240A	240	Missense	distal	-3	no	14.404	14.385	EPSD	TCGA;ICGC;COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	Q9NXR1	NDE1	P24941	CDK2	T243	L245F	245	Missense	proximal	2	no	14.404	14.761	EPSD	TCGA;ICGC;COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	Q9NXR1	NDE1	P24941	CDK2	T243	T246I	246	Missense	distal	3	no	14.404	13.850	EPSD	TCGA;ICGC;COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	Q9NXR1	NDE1	P24941	CDK2	T246	R250W	250	Missense	distal	4	no	12.046	11.687	EPSD	TCGA;ICGC;COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	Q9NXR1	NDE1	P24941	CDK2	T246	T240A	240	Missense	distal	-6	no	12.046	12.045	EPSD	TCGA;ICGC;COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	Q9NXR1	NDE1	P24941	CDK2	T246	L245F	245	Missense	proximal	-1	no	12.046	13.012	EPSD	TCGA;ICGC;COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	Q9NXR1	NDE1	P24941	CDK2	T246	T246I	246	Missense	central	0	yes	12.046	0.000	EPSD	TCGA;ICGC;COSMIC	8.148	Loss
CMGC_CDK_CDK2_CDK2_ST	Q8WUM0	NUP133	P24941	CDK2	S7	T13S	13	Missense	distal	6	no	13.860	13.854	EPSD	TCGA;ICGC;COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	Q8WUM0	NUP133	P24941	CDK2	T10	T13S	13	Missense	distal	3	no	11.733	11.881	EPSD	TCGA;ICGC;COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	Q8WUM0	NUP133	P24941	CDK2	T28	P29S	29	Missense	proximal	1	no	11.885	0.619	EPSD	TCGA;COSMIC	8.148	Loss
CMGC_CDK_CDK2_CDK2_ST	Q8WUM0	NUP133	P24941	CDK2	T63	R66Q	66	Missense	distal	3	no	16.237	14.493	EPSD	TCGA;COSMIC;CCLE	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	Q8WUM0	NUP133	P24941	CDK2	T63	T65I	65	Missense	proximal	2	no	16.237	16.391	EPSD	TCGA;COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	Q8WUM0	NUP133	P24941	CDK2	S131	V138I	138	Missense	distal	7	no	13.527	13.326	EPSD	TCGA;COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	Q8WUM0	NUP133	P24941	CDK2	S131	S137F	137	Missense	distal	6	no	13.527	13.508	EPSD	TCGA;COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	Q8WUM0	NUP133	P24941	CDK2	S267	F263L	263	Missense	distal	-4	no	9.034	9.583	EPSD	TCGA;COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	Q8WUM0	NUP133	P24941	CDK2	S267	S260C	260	Missense	distal	-7	no	9.034	9.485	EPSD	TCGA;COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	Q8WUM0	NUP133	P24941	CDK2	S267	G264V	264	Missense	distal	-3	no	9.034	9.073	EPSD	TCGA;COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	Q8WUM0	NUP133	P24941	CDK2	S267	S260F	260	Missense	distal	-7	no	9.034	9.585	EPSD	TCGA;COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	Q8WUM0	NUP133	P24941	CDK2	S309	W310G	310	Missense	proximal	1	no	1.723	9.633	EPSD	TCGA;COSMIC	8.148	Gain
CMGC_CDK_CDK2_CDK2_ST	Q8WUM0	NUP133	P24941	CDK2	T632	G631R	631	Missense	proximal	-1	no	12.587	12.109	EPSD	TCGA;COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	Q8WUM0	NUP133	P24941	CDK2	T632	L639F	639	Missense	distal	7	no	12.587	13.258	EPSD	TCGA;COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	Q8WUM0	NUP133	P24941	CDK2	T632	M634V	634	Missense	proximal	2	no	12.587	12.499	EPSD	TCGA	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	Q8WUM0	NUP133	P24941	CDK2	T684	P685L	685	Missense	proximal	1	no	10.580	0.760	EPSD	TCGA;COSMIC	8.148	Loss
CMGC_CDK_CDK2_CDK2_ST	Q8WUM0	NUP133	P24941	CDK2	T684	S681C	681	Missense	distal	-3	no	10.580	10.588	EPSD	TCGA;COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	Q8WUM0	NUP133	P24941	CDK2	T684	N682S	682	Missense	proximal	-2	no	10.580	11.272	EPSD	TCGA;COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	Q8WUM0	NUP133	P24941	CDK2	S740	M735L	735	Missense	distal	-5	no	8.777	8.682	EPSD	TCGA;COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	Q8WUM0	NUP133	P24941	CDK2	S1086	D1087G	1087	Missense	proximal	1	no	8.086	9.017	EPSD	TCGA;COSMIC	8.148	Gain
CMGC_CDK_CDK2_CDK2_ST	P46013	MKI67	P24941	CDK2	S152	P155S	155	Missense	distal	3	no	8.241	8.275	EPSD	TCGA;ICGC;COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	P46013	MKI67	P24941	CDK2	S152	P155H	155	Missense	distal	3	no	8.241	9.263	EPSD	TCGA;ICGC;COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	P46013	MKI67	P24941	CDK2	S235	P236L	236	Missense	proximal	1	no	13.170	3.349	EPSD	TCGA;ICGC;COSMIC	8.148	Loss
CMGC_CDK_CDK2_CDK2_ST	P46013	MKI67	P24941	CDK2	S235	P236S	236	Missense	proximal	1	no	13.170	1.904	EPSD	TCGA;ICGC;COSMIC	8.148	Loss
CMGC_CDK_CDK2_CDK2_ST	P46013	MKI67	P24941	CDK2	S235	F237S	237	Missense	proximal	2	no	13.170	12.986	EPSD	TCGA;ICGC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	P46013	MKI67	P24941	CDK2	S308	E310K	310	Missense	proximal	2	no	13.943	13.705	EPSD	TCGA;ICGC;COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	P46013	MKI67	P24941	CDK2	S308	E305Q	305	Missense	distal	-3	no	13.943	13.827	EPSD	TCGA;ICGC;COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	P46013	MKI67	P24941	CDK2	T328	Q327K	327	Missense	proximal	-1	no	17.767	17.974	EPSD	TCGA;ICGC;COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	P46013	MKI67	P24941	CDK2	T328	V323L	323	Missense	distal	-5	no	17.767	17.748	EPSD	TCGA;ICGC;COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	P46013	MKI67	P24941	CDK2	T328	A335T	335	Missense	distal	7	no	17.767	17.078	EPSD	TCGA;ICGC;COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	P46013	MKI67	P24941	CDK2	T328	V333A	333	Missense	distal	5	no	17.767	17.810	EPSD	TCGA;ICGC;COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	P46013	MKI67	P24941	CDK2	T347	E341Q	341	Missense	distal	-6	no	9.044	9.045	EPSD	TCGA;ICGC;COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	P46013	MKI67	P24941	CDK2	S357	K362N	362	Missense	distal	5	no	15.647	15.804	PhosphoSitePlus	TCGA;ICGC;COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	P46013	MKI67	P24941	CDK2	S357	S357Y	357	Missense	central	0	yes	15.647	0.000	PhosphoSitePlus	TCGA;ICGC;COSMIC;GDSC	8.148	Loss
CMGC_CDK_CDK2_CDK2_ST	P46013	MKI67	P24941	CDK2	S357	Q355H	355	Missense	proximal	-2	no	15.647	15.204	PhosphoSitePlus	TCGA;ICGC;COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	P46013	MKI67	P24941	CDK2	S357	K364R	364	Missense	distal	7	no	15.647	16.423	PhosphoSitePlus	TCGA;ICGC;COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	P46013	MKI67	P24941	CDK2	T369	L366M	366	Missense	distal	-3	no	7.875	8.315	EPSD	TCGA;ICGC	8.148	Gain
CMGC_CDK_CDK2_CDK2_ST	P46013	MKI67	P24941	CDK2	T401	D407H	407	Missense	distal	6	no	17.455	17.465	EPSD	TCGA;ICGC;COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	P46013	MKI67	P24941	CDK2	T401	A403P	403	Missense	proximal	2	no	17.455	17.430	EPSD	TCGA;ICGC;COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	P46013	MKI67	P24941	CDK2	T525	D518N	518	Missense	distal	-7	no	17.005	16.682	EPSD	TCGA;COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	P46013	MKI67	P24941	CDK2	T525	D518H	518	Missense	distal	-7	no	17.005	16.887	EPSD	TCGA;COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	P46013	MKI67	P24941	CDK2	T525	P523A	523	Missense	proximal	-2	no	17.005	17.021	EPSD	TCGA;COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	P46013	MKI67	P24941	CDK2	T525	G530V	530	Missense	distal	5	no	17.005	16.845	EPSD	TCGA;COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	P46013	MKI67	P24941	CDK2	T525	P526S	526	Missense	proximal	1	no	17.005	5.739	EPSD	TCGA;COSMIC	8.148	Loss
CMGC_CDK_CDK2_CDK2_ST	P46013	MKI67	P24941	CDK2	T543	L539V	539	Missense	distal	-4	no	11.508	11.518	EPSD	TCGA;COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	P46013	MKI67	P24941	CDK2	T543	P544L	544	Missense	proximal	1	no	11.508	1.687	EPSD	TCGA;COSMIC	8.148	Loss
CMGC_CDK_CDK2_CDK2_ST	P46013	MKI67	P24941	CDK2	T543	M541V	541	Missense	proximal	-2	no	11.508	12.943	EPSD	TCGA	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	P46013	MKI67	P24941	CDK2	T543	S538Y	538	Missense	distal	-5	no	11.508	11.577	EPSD	TCGA;COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	P46013	MKI67	P24941	CDK2	S579	L576S	576	Missense	distal	-3	no	12.199	12.366	EPSD	TCGA;COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	P46013	MKI67	P24941	CDK2	S584	A591G	591	Missense	distal	7	no	16.862	17.148	EPSD	TCGA	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	P46013	MKI67	P24941	CDK2	T588	A591G	591	Missense	distal	3	no	12.402	12.813	EPSD	TCGA	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	P46013	MKI67	P24941	CDK2	S609	E612K	612	Missense	distal	3	no	6.764	8.850	EPSD	TCGA;COSMIC	8.148	Gain
CMGC_CDK_CDK2_CDK2_ST	P46013	MKI67	P24941	CDK2	T694	V699E	699	Missense	distal	5	no	15.027	15.139	EPSD	TCGA;COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	P46013	MKI67	P24941	CDK2	S713	S713P	713	Missense	central	0	yes	15.083	0.000	EPSD	TCGA	8.148	Loss
CMGC_CDK_CDK2_CDK2_ST	P46013	MKI67	P24941	CDK2	S713	A711T	711	Missense	proximal	-2	no	15.083	15.033	EPSD	TCGA;COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	P46013	MKI67	P24941	CDK2	S713	T716I	716	Missense	distal	3	no	15.083	14.529	EPSD	TCGA;COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	P46013	MKI67	P24941	CDK2	T844	V841I	841	Missense	distal	-3	no	12.936	12.813	EPSD	TCGA;COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	P46013	MKI67	P24941	CDK2	T1017	P1014S	1014	Missense	distal	-3	no	14.787	14.882	EPSD	TCGA;COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	P46013	MKI67	P24941	CDK2	T1019	P1012Q	1012	Missense	distal	-7	no	9.528	9.485	EPSD	TCGA;COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	P46013	MKI67	P24941	CDK2	T1019	P1014S	1014	Missense	distal	-5	no	9.528	9.483	EPSD	TCGA;COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	P46013	MKI67	P24941	CDK2	T1054	E1057K	1057	Missense	distal	3	no	6.789	8.874	EPSD	TCGA;COSMIC	8.148	Gain
CMGC_CDK_CDK2_CDK2_ST	P46013	MKI67	P24941	CDK2	S1071	L1076P	1076	Missense	distal	5	no	12.202	12.162	EPSD	TCGA;COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	P46013	MKI67	P24941	CDK2	S1071	E1070K	1070	Missense	proximal	-1	no	12.202	11.317	EPSD	TCGA	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	P46013	MKI67	P24941	CDK2	S1071	P1072S	1072	Missense	proximal	1	no	12.202	0.936	EPSD	TCGA;COSMIC	8.148	Loss
CMGC_CDK_CDK2_CDK2_ST	P46013	MKI67	P24941	CDK2	S1071	K1073E	1073	Missense	proximal	2	no	12.202	12.440	EPSD	TCGA;COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	P46013	MKI67	P24941	CDK2	T1083	L1076P	1076	Missense	distal	-7	no	10.265	10.259	EPSD	TCGA;COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	P46013	MKI67	P24941	CDK2	T1083	R1090T	1090	Missense	distal	7	no	10.265	9.471	EPSD	TCGA;COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	P46013	MKI67	P24941	CDK2	T1083	R1081H	1081	Missense	proximal	-2	no	10.265	10.491	EPSD	TCGA;COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	P46013	MKI67	P24941	CDK2	T1091	E1094Q	1094	Missense	distal	3	no	13.129	12.482	EPSD	TCGA;COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	P46013	MKI67	P24941	CDK2	T1091	R1090T	1090	Missense	proximal	-1	no	13.129	12.296	EPSD	TCGA;COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	P46013	MKI67	P24941	CDK2	T1111	P1112S	1112	Missense	proximal	1	no	12.959	1.693	EPSD	TCGA	8.148	Loss
CMGC_CDK_CDK2_CDK2_ST	P46013	MKI67	P24941	CDK2	T1111	P1114S	1114	Missense	distal	3	no	12.959	12.993	EPSD	TCGA;COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	P46013	MKI67	P24941	CDK2	T1111	G1104A	1104	Missense	distal	-7	no	12.959	12.799	EPSD	TCGA;COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	P46013	MKI67	P24941	CDK2	T1120	P1114S	1114	Missense	distal	-6	no	9.578	9.577	EPSD	TCGA;COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	P46013	MKI67	P24941	CDK2	S1131	S1131C	1131	Missense	central	0	yes	15.154	0.000	EPSD	TCGA;COSMIC	8.148	Loss
CMGC_CDK_CDK2_CDK2_ST	P46013	MKI67	P24941	CDK2	S1131	P1132S	1132	Missense	proximal	1	no	15.154	3.888	EPSD	TCGA;COSMIC	8.148	Loss
CMGC_CDK_CDK2_CDK2_ST	P46013	MKI67	P24941	CDK2	S1131	P1133L	1133	Missense	proximal	2	no	15.154	15.047	EPSD	TCGA;COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	P46013	MKI67	P24941	CDK2	S1131	P1132L	1132	Missense	proximal	1	no	15.154	5.333	EPSD	TCGA;COSMIC	8.148	Loss
CMGC_CDK_CDK2_CDK2_ST	P46013	MKI67	P24941	CDK2	S1131	S1136T	1136	Missense	distal	5	no	15.154	15.229	EPSD	TCGA;COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	P46013	MKI67	P24941	CDK2	S1131	C1129R	1129	Missense	proximal	-2	no	15.154	14.979	EPSD	TCGA;COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	P46013	MKI67	P24941	CDK2	T1139	P1140L	1140	Missense	proximal	1	no	16.279	6.459	EPSD	TCGA;COSMIC	8.148	Loss
CMGC_CDK_CDK2_CDK2_ST	P46013	MKI67	P24941	CDK2	T1139	P1132S	1132	Missense	distal	-7	no	16.279	16.100	EPSD	TCGA;COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	P46013	MKI67	P24941	CDK2	T1139	P1132L	1132	Missense	distal	-7	no	16.279	16.285	EPSD	TCGA;COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	P46013	MKI67	P24941	CDK2	T1139	S1136T	1136	Missense	distal	-3	no	16.279	16.145	EPSD	TCGA;COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	P46013	MKI67	P24941	CDK2	T1167	M1174I	1174	Missense	distal	7	no	13.741	13.253	EPSD	TCGA;COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	P46013	MKI67	P24941	CDK2	T1176	M1174I	1174	Missense	proximal	-2	no	11.890	13.820	EPSD	TCGA;COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	P46013	MKI67	P24941	CDK2	T1176	T1176M	1176	Missense	central	0	yes	11.890	0.000	EPSD	TCGA;COSMIC	8.148	Loss
CMGC_CDK_CDK2_CDK2_ST	P46013	MKI67	P24941	CDK2	T1176	G1181E	1181	Missense	distal	5	no	11.890	11.842	EPSD	TCGA;COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	P46013	MKI67	P24941	CDK2	T1193	D1199H	1199	Missense	distal	6	no	11.331	11.341	EPSD	TCGA;COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	P46013	MKI67	P24941	CDK2	T1193	D1186Y	1186	Missense	distal	-7	no	11.331	11.215	EPSD	TCGA	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	P46013	MKI67	P24941	CDK2	T1193	K1197E	1197	Missense	distal	4	no	11.331	10.946	EPSD	TCGA;COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	P46013	MKI67	P24941	CDK2	T1193	G1192E	1192	Missense	proximal	-1	no	11.331	11.067	EPSD	TCGA;COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	P46013	MKI67	P24941	CDK2	T1213	P1214T	1214	Missense	proximal	1	no	13.927	3.970	EPSD	TCGA;COSMIC	8.148	Loss
CMGC_CDK_CDK2_CDK2_ST	P46013	MKI67	P24941	CDK2	T1213	A1218T	1218	Missense	distal	5	no	13.927	13.891	EPSD	TCGA;COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	P46013	MKI67	P24941	CDK2	T1233	Q1232H	1232	Missense	proximal	-1	no	13.147	13.574	EPSD	TCGA;COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	P46013	MKI67	P24941	CDK2	S1253	P1250L	1250	Missense	distal	-3	no	13.686	13.615	EPSD	TCGA;COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	P46013	MKI67	P24941	CDK2	S1253	P1250S	1250	Missense	distal	-3	no	13.686	13.781	EPSD	TCGA;COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	P46013	MKI67	P24941	CDK2	T1261	S1264I	1264	Missense	distal	3	no	14.931	14.229	EPSD	TCGA;COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	P46013	MKI67	P24941	CDK2	T1261	R1268Q	1268	Missense	distal	7	no	14.931	14.286	EPSD	TCGA;COSMIC;GDSC;CCLE	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	P46013	MKI67	P24941	CDK2	T1298	A1295V	1295	Missense	distal	-3	no	8.539	8.740	EPSD	TCGA;COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	P46013	MKI67	P24941	CDK2	T1315	P1316A	1316	Missense	proximal	1	no	13.896	-0.508	EPSD	TCGA;COSMIC	8.148	Loss
CMGC_CDK_CDK2_CDK2_ST	P46013	MKI67	P24941	CDK2	T1327	K1330N	1330	Missense	distal	3	no	8.606	5.336	EPSD	TCGA;COSMIC	8.148	Loss
CMGC_CDK_CDK2_CDK2_ST	P46013	MKI67	P24941	CDK2	T1327	Q1334H	1334	Missense	distal	7	no	8.606	8.893	EPSD	TCGA;COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	P46013	MKI67	P24941	CDK2	T1327	E1324D	1324	Missense	distal	-3	no	8.606	8.497	EPSD	TCGA;COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	P46013	MKI67	P24941	CDK2	T1327	G1328S	1328	Missense	proximal	1	no	8.606	4.653	EPSD	TCGA;COSMIC;CCLE	8.148	Loss
CMGC_CDK_CDK2_CDK2_ST	P46013	MKI67	P24941	CDK2	T1327	R1331K	1331	Missense	distal	4	no	8.606	9.128	EPSD	TCGA;COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	P46013	MKI67	P24941	CDK2	T1327	P1333A	1333	Missense	distal	6	no	8.606	8.602	EPSD	TCGA;COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	P46013	MKI67	P24941	CDK2	T1335	K1330N	1330	Missense	distal	-5	no	13.492	13.508	EPSD	TCGA;COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	P46013	MKI67	P24941	CDK2	T1335	Q1334H	1334	Missense	proximal	-1	no	13.492	13.918	EPSD	TCGA;COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	P46013	MKI67	P24941	CDK2	T1335	E1339K	1339	Missense	distal	4	no	13.492	13.876	EPSD	TCGA;COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	P46013	MKI67	P24941	CDK2	T1335	P1336A	1336	Missense	proximal	1	no	13.492	-0.912	EPSD	TCGA;COSMIC	8.148	Loss
CMGC_CDK_CDK2_CDK2_ST	P46013	MKI67	P24941	CDK2	T1335	E1338K	1338	Missense	distal	3	no	13.492	15.577	EPSD	TCGA;COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	P46013	MKI67	P24941	CDK2	T1335	G1328S	1328	Missense	distal	-7	no	13.492	12.987	EPSD	TCGA;COSMIC;CCLE	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	P46013	MKI67	P24941	CDK2	T1335	R1331K	1331	Missense	distal	-4	no	13.492	13.654	EPSD	TCGA;COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	P46013	MKI67	P24941	CDK2	T1335	P1336S	1336	Missense	proximal	1	no	13.492	2.226	EPSD	TCGA;COSMIC	8.148	Loss
CMGC_CDK_CDK2_CDK2_ST	P46013	MKI67	P24941	CDK2	T1335	P1333A	1333	Missense	proximal	-2	no	13.492	13.508	EPSD	TCGA;COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	P46013	MKI67	P24941	CDK2	T1335	Q1341H	1341	Missense	distal	6	no	13.492	13.481	EPSD	TCGA;COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	P46013	MKI67	P24941	CDK2	T1347	E1351K	1351	Missense	distal	4	no	8.734	9.119	EPSD	TCGA;COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	P46013	MKI67	P24941	CDK2	T1347	Q1341H	1341	Missense	distal	-6	no	8.734	8.735	EPSD	TCGA;COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	P46013	MKI67	P24941	CDK2	T1355	E1351K	1351	Missense	distal	-4	no	13.034	12.722	EPSD	TCGA;COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	P46013	MKI67	P24941	CDK2	T1355	E1361D	1361	Missense	distal	6	no	13.034	13.021	EPSD	TCGA;COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	P46013	MKI67	P24941	CDK2	S1376	E1379D	1379	Missense	distal	3	no	12.972	10.536	EPSD	TCGA;COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	P46013	MKI67	P24941	CDK2	S1376	E1374K	1374	Missense	proximal	-2	no	12.972	13.573	EPSD	TCGA;COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	P46013	MKI67	P24941	CDK2	S1376	P1378S	1378	Missense	proximal	2	no	12.972	13.038	EPSD	TCGA;COSMIC;GDSC;CCLE	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	P46013	MKI67	P24941	CDK2	T1383	E1379D	1379	Missense	distal	-4	no	14.098	14.395	EPSD	TCGA;COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	P46013	MKI67	P24941	CDK2	T1383	P1378S	1378	Missense	distal	-5	no	14.098	14.054	EPSD	TCGA;COSMIC;GDSC;CCLE	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	P46013	MKI67	P24941	CDK2	T1418	D1421H	1421	Missense	distal	3	no	7.130	9.966	EPSD	TCGA;COSMIC	8.148	Gain
CMGC_CDK_CDK2_CDK2_ST	P46013	MKI67	P24941	CDK2	T1449	H1454Q	1454	Missense	distal	5	no	8.370	8.252	EPSD	TCGA;COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	P46013	MKI67	P24941	CDK2	T1484	T1485P	1485	Missense	proximal	1	no	4.149	14.106	EPSD	TCGA;COSMIC	8.148	Gain
CMGC_CDK_CDK2_CDK2_ST	P46013	MKI67	P24941	CDK2	T1485	K1491E	1491	Missense	distal	6	no	8.583	8.572	EPSD	TCGA;COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	P46013	MKI67	P24941	CDK2	T1485	I1492M	1492	Missense	distal	7	no	8.583	9.071	EPSD	TCGA;COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	P46013	MKI67	P24941	CDK2	T1485	T1484M	1484	Missense	proximal	-1	no	8.583	9.896	EPSD	TCGA;COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	P46013	MKI67	P24941	CDK2	T1485	H1486Q	1486	Missense	proximal	1	no	8.583	7.430	EPSD	TCGA;COSMIC	8.148	Loss
CMGC_CDK_CDK2_CDK2_ST	P46013	MKI67	P24941	CDK2	T1485	T1485P	1485	Missense	central	0	yes	8.583	0.000	EPSD	TCGA;COSMIC	8.148	Loss
CMGC_CDK_CDK2_CDK2_ST	P46013	MKI67	P24941	CDK2	T1503	D1499H	1499	Missense	distal	-4	no	14.340	13.210	EPSD	TCGA;COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	P46013	MKI67	P24941	CDK2	T1531	M1538V	1538	Missense	distal	7	no	12.626	12.339	EPSD	TCGA	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	P46013	MKI67	P24941	CDK2	T1531	A1526T	1526	Missense	distal	-5	no	12.626	12.600	EPSD	TCGA;COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	P46013	MKI67	P24941	CDK2	T1531	A1534V	1534	Missense	distal	3	no	12.626	13.746	EPSD	TCGA;COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	P46013	MKI67	P24941	CDK2	T1531	F1524L	1524	Missense	distal	-7	no	12.626	12.260	EPSD	TCGA;COSMIC;GDSC;CCLE	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	P46013	MKI67	P24941	CDK2	T1540	M1538V	1538	Missense	proximal	-2	no	10.897	12.332	EPSD	TCGA	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	P46013	MKI67	P24941	CDK2	T1540	V1545I	1545	Missense	distal	5	no	10.897	11.023	EPSD	TCGA;COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	P46013	MKI67	P24941	CDK2	T1540	A1534V	1534	Missense	distal	-6	no	10.897	10.900	EPSD	TCGA;COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	P46013	MKI67	P24941	CDK2	T1540	H1539R	1539	Missense	proximal	-1	no	10.897	11.349	EPSD	TCGA;COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	P46013	MKI67	P24941	CDK2	S1546	A1553S	1553	Missense	distal	7	no	11.331	10.794	EPSD	TCGA;COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	P46013	MKI67	P24941	CDK2	S1546	A1553T	1553	Missense	distal	7	no	11.331	10.642	EPSD	TCGA;COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	P46013	MKI67	P24941	CDK2	S1546	V1545I	1545	Missense	proximal	-1	no	11.331	11.357	EPSD	TCGA;COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	P46013	MKI67	P24941	CDK2	S1546	H1539R	1539	Missense	distal	-7	no	11.331	11.551	EPSD	TCGA;COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	P46013	MKI67	P24941	CDK2	T1557	A1553S	1553	Missense	distal	-4	no	11.079	11.493	EPSD	TCGA;COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	P46013	MKI67	P24941	CDK2	T1557	L1562P	1562	Missense	distal	5	no	11.079	11.040	EPSD	TCGA;COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	P46013	MKI67	P24941	CDK2	T1557	A1553T	1553	Missense	distal	-4	no	11.079	11.305	EPSD	TCGA;COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	P46013	MKI67	P24941	CDK2	T1557	K1561E	1561	Missense	distal	4	no	11.079	10.695	EPSD	TCGA;COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	P46013	MKI67	P24941	CDK2	T1577	K1572N	1572	Missense	distal	-5	no	13.129	13.145	EPSD	TCGA;COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	P46013	MKI67	P24941	CDK2	T1577	R1574W	1574	Missense	distal	-3	no	13.129	13.210	EPSD	TCGA;COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	P46013	MKI67	P24941	CDK2	S1679	F1676C	1676	Missense	distal	-3	no	10.457	10.373	EPSD	TCGA;COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	P46013	MKI67	P24941	CDK2	S1679	E1678K	1678	Missense	proximal	-1	no	10.457	9.572	EPSD	TCGA	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	P46013	MKI67	P24941	CDK2	T1691	R1698T	1698	Missense	distal	7	no	10.345	9.552	EPSD	TCGA;COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	P46013	MKI67	P24941	CDK2	T1691	A1687T	1687	Missense	distal	-4	no	10.345	10.570	EPSD	TCGA;COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	P46013	MKI67	P24941	CDK2	T1699	E1705K	1705	Missense	distal	6	no	13.662	13.673	EPSD	TCGA;COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	P46013	MKI67	P24941	CDK2	T1699	R1698T	1698	Missense	proximal	-1	no	13.662	12.828	EPSD	TCGA;COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	P46013	MKI67	P24941	CDK2	T1719	E1715K	1715	Missense	distal	-4	no	11.953	11.641	EPSD	TCGA;COSMIC;CCLE	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	P46013	MKI67	P24941	CDK2	S1721	E1715K	1715	Missense	distal	-6	no	8.531	8.529	EPSD	TCGA;COSMIC;CCLE	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	P46013	MKI67	P24941	CDK2	T1747	S1750R	1750	Missense	distal	3	no	15.182	16.866	EPSD	TCGA;COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	P46013	MKI67	P24941	CDK2	T1775	R1772W	1772	Missense	distal	-3	no	12.877	12.958	EPSD	TCGA;COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	P46013	MKI67	P24941	CDK2	T1775	G1779V	1779	Missense	distal	4	no	12.877	13.224	EPSD	TCGA;COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	P46013	MKI67	P24941	CDK2	T1775	T1775M	1775	Missense	central	0	yes	12.877	0.000	EPSD	TCGA;COSMIC	8.148	Loss
CMGC_CDK_CDK2_CDK2_ST	P46013	MKI67	P24941	CDK2	T1784	T1784A	1784	Missense	central	0	yes	9.030	0.000	EPSD	TCGA;COSMIC	8.148	Loss
CMGC_CDK_CDK2_CDK2_ST	P46013	MKI67	P24941	CDK2	T1784	T1784I	1784	Missense	central	0	yes	9.030	0.000	EPSD	TCGA;COSMIC	8.148	Loss
CMGC_CDK_CDK2_CDK2_ST	P46013	MKI67	P24941	CDK2	T1784	G1779V	1779	Missense	distal	-5	no	9.030	8.982	EPSD	TCGA;COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	P46013	MKI67	P24941	CDK2	T1801	D1807H	1807	Missense	distal	6	no	13.763	13.774	EPSD	TCGA;COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	P46013	MKI67	P24941	CDK2	T1801	T1797M	1797	Missense	distal	-4	no	13.763	12.849	EPSD	TCGA;COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	P46013	MKI67	P24941	CDK2	T1801	V1803A	1803	Missense	proximal	2	no	13.763	13.665	EPSD	TCGA	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	P46013	MKI67	P24941	CDK2	T1841	R1836T	1836	Missense	distal	-5	no	11.174	11.126	EPSD	TCGA;COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	P46013	MKI67	P24941	CDK2	T1841	P1842L	1842	Missense	proximal	1	no	11.174	1.353	EPSD	TCGA;COSMIC	8.148	Loss
CMGC_CDK_CDK2_CDK2_ST	P46013	MKI67	P24941	CDK2	T1848	T1849P	1849	Missense	proximal	1	no	1.821	11.778	EPSD	TCGA;COSMIC	8.148	Gain
CMGC_CDK_CDK2_CDK2_ST	P46013	MKI67	P24941	CDK2	S1861	P1862L	1862	Missense	proximal	1	no	12.594	2.773	EPSD	TCGA;COSMIC;GDSC	8.148	Loss
CMGC_CDK_CDK2_CDK2_ST	P46013	MKI67	P24941	CDK2	T1869	P1862L	1862	Missense	distal	-7	no	14.825	14.831	EPSD	TCGA;COSMIC;GDSC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	P46013	MKI67	P24941	CDK2	T1869	T1871A	1871	Missense	proximal	2	no	14.825	15.027	EPSD	TCGA;ICGC;COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	P46013	MKI67	P24941	CDK2	T1897	F1890C	1890	Missense	distal	-7	no	12.392	12.292	EPSD	TCGA;COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	P46013	MKI67	P24941	CDK2	T1923	V1925M	1925	Missense	proximal	2	no	13.948	14.037	EPSD	TCGA	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	P46013	MKI67	P24941	CDK2	T1923	F1920S	1920	Missense	distal	-3	no	13.948	13.857	EPSD	TCGA	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	P46013	MKI67	P24941	CDK2	T1923	D1916Y	1916	Missense	distal	-7	no	13.948	13.833	EPSD	TCGA;COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	P46013	MKI67	P24941	CDK2	T1943	A1948V	1948	Missense	distal	5	no	13.434	13.391	EPSD	TCGA;COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	P46013	MKI67	P24941	CDK2	T1943	Q1942H	1942	Missense	proximal	-1	no	13.434	13.861	EPSD	TCGA	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	P46013	MKI67	P24941	CDK2	T1963	E1969K	1969	Missense	distal	6	no	13.140	13.151	EPSD	TCGA;COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	P46013	MKI67	P24941	CDK2	T1972	E1969K	1969	Missense	distal	-3	no	9.746	9.531	EPSD	TCGA;COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	P46013	MKI67	P24941	CDK2	T1972	I1976S	1976	Missense	distal	4	no	9.746	9.788	EPSD	TCGA;COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	P46013	MKI67	P24941	CDK2	S1983	P1986A	1986	Missense	distal	3	no	13.963	13.451	EPSD	TCGA;COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	P46013	MKI67	P24941	CDK2	S1983	I1976S	1976	Missense	distal	-7	no	13.963	13.589	EPSD	TCGA;COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	P46013	MKI67	P24941	CDK2	S1983	C1981Y	1981	Missense	proximal	-2	no	13.963	14.460	EPSD	TCGA;COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	P46013	MKI67	P24941	CDK2	T1991	P1986A	1986	Missense	distal	-5	no	14.501	14.525	EPSD	TCGA;COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	P46013	MKI67	P24941	CDK2	T2021	S2022P	2022	Missense	proximal	1	no	4.299	15.564	EPSD	TCGA	8.148	Gain
CMGC_CDK_CDK2_CDK2_ST	P46013	MKI67	P24941	CDK2	T2028	T2021M	2021	Missense	distal	-7	no	7.687	8.191	EPSD	TCGA;COSMIC	8.148	Gain
CMGC_CDK_CDK2_CDK2_ST	P46013	MKI67	P24941	CDK2	T2057	G2058E	2058	Missense	proximal	1	no	10.135	8.281	EPSD	TCGA;COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	P46013	MKI67	P24941	CDK2	T2057	G2058R	2058	Missense	proximal	1	no	10.135	7.648	EPSD	TCGA;COSMIC	8.148	Loss
CMGC_CDK_CDK2_CDK2_ST	P46013	MKI67	P24941	CDK2	T2057	N2054D	2054	Missense	distal	-3	no	10.135	10.179	EPSD	TCGA;COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	P46013	MKI67	P24941	CDK2	T2065	E2069Q	2069	Missense	distal	4	no	13.372	13.416	EPSD	TCGA;COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	P46013	MKI67	P24941	CDK2	T2065	P2066A	2066	Missense	proximal	1	no	13.372	-1.031	EPSD	TCGA;COSMIC	8.148	Loss
CMGC_CDK_CDK2_CDK2_ST	P46013	MKI67	P24941	CDK2	T2065	G2058E	2058	Missense	distal	-7	no	13.372	13.138	EPSD	TCGA;COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	P46013	MKI67	P24941	CDK2	T2065	G2058R	2058	Missense	distal	-7	no	13.372	13.391	EPSD	TCGA;COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	P46013	MKI67	P24941	CDK2	T2085	E2090K	2090	Missense	distal	5	no	14.490	14.357	EPSD	TCGA;COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	P46013	MKI67	P24941	CDK2	T2085	Q2084H	2084	Missense	proximal	-1	no	14.490	14.917	EPSD	TCGA;COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	P46013	MKI67	P24941	CDK2	T2085	E2090D	2090	Missense	distal	5	no	14.490	14.585	EPSD	TCGA	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	P46013	MKI67	P24941	CDK2	T2085	T2089I	2089	Missense	distal	4	no	14.490	14.178	EPSD	TCGA;COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	P46013	MKI67	P24941	CDK2	T2094	E2090D	2090	Missense	distal	-4	no	7.906	8.203	EPSD	TCGA	8.148	Gain
CMGC_CDK_CDK2_CDK2_ST	P46013	MKI67	P24941	CDK2	S2105	K2100E	2100	Missense	distal	-5	no	14.933	14.967	EPSD	TCGA;COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	P46013	MKI67	P24941	CDK2	S2105	A2102V	2102	Missense	distal	-3	no	14.933	15.134	EPSD	TCGA;COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	P46013	MKI67	P24941	CDK2	S2105	A2102S	2102	Missense	distal	-3	no	14.933	15.086	EPSD	TCGA;COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	P46013	MKI67	P24941	CDK2	S2105	P2106S	2106	Missense	proximal	1	no	14.933	3.667	EPSD	TCGA;COSMIC	8.148	Loss
CMGC_CDK_CDK2_CDK2_ST	P46013	MKI67	P24941	CDK2	S2105	M2111V	2111	Missense	distal	6	no	14.933	14.950	EPSD	TCGA;COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	P46013	MKI67	P24941	CDK2	S2105	P2108S	2108	Missense	distal	3	no	14.933	14.967	EPSD	TCGA;COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	P46013	MKI67	P24941	CDK2	T2113	P2106S	2106	Missense	distal	-7	no	12.560	12.380	EPSD	TCGA;COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	P46013	MKI67	P24941	CDK2	T2113	M2111V	2111	Missense	proximal	-2	no	12.560	13.995	EPSD	TCGA;COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	P46013	MKI67	P24941	CDK2	T2113	R2120W	2120	Missense	distal	7	no	12.560	12.959	EPSD	TCGA;COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	P46013	MKI67	P24941	CDK2	T2113	P2108S	2108	Missense	distal	-5	no	12.560	12.516	EPSD	TCGA;COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	P46013	MKI67	P24941	CDK2	T2123	R2120W	2120	Missense	distal	-3	no	15.069	15.150	EPSD	TCGA;COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	P46013	MKI67	P24941	CDK2	T2175	D2169N	2169	Missense	distal	-6	no	9.998	9.999	EPSD	TCGA;COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	P46013	MKI67	P24941	CDK2	T2175	G2176D	2176	Missense	proximal	1	no	9.998	9.066	EPSD	TCGA	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	P46013	MKI67	P24941	CDK2	T2183	P2184A	2184	Missense	proximal	1	no	13.466	-0.938	EPSD	TCGA;COSMIC	8.148	Loss
CMGC_CDK_CDK2_CDK2_ST	P46013	MKI67	P24941	CDK2	T2183	A2188S	2188	Missense	distal	5	no	13.466	13.355	EPSD	TCGA;COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	P46013	MKI67	P24941	CDK2	T2183	G2176D	2176	Missense	distal	-7	no	13.466	13.383	EPSD	TCGA	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	P46013	MKI67	P24941	CDK2	T2203	D2208Y	2208	Missense	distal	5	no	8.173	8.073	EPSD	TCGA	8.148	Loss
CMGC_CDK_CDK2_CDK2_ST	P46013	MKI67	P24941	CDK2	T2203	L2197V	2197	Missense	distal	-6	no	8.173	8.175	EPSD	TCGA;COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	P46013	MKI67	P24941	CDK2	T2203	L2197F	2197	Missense	distal	-6	no	8.173	8.177	EPSD	TCGA;COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	P46013	MKI67	P24941	CDK2	T2212	D2208Y	2208	Missense	distal	-4	no	10.202	10.141	EPSD	TCGA	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	P46013	MKI67	P24941	CDK2	T2212	T2212A	2212	Missense	central	0	yes	10.202	0.000	EPSD	TCGA;COSMIC	8.148	Loss
CMGC_CDK_CDK2_CDK2_ST	P46013	MKI67	P24941	CDK2	T2212	T2211R	2211	Missense	proximal	-1	no	10.202	11.036	EPSD	TCGA;COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	P46013	MKI67	P24941	CDK2	S2223	R2222I	2222	Missense	proximal	-1	no	12.346	11.758	EPSD	TCGA;COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	P46013	MKI67	P24941	CDK2	T2231	T2231A	2231	Missense	central	0	yes	12.458	0.000	EPSD	TCGA;COSMIC	8.148	Loss
CMGC_CDK_CDK2_CDK2_ST	P46013	MKI67	P24941	CDK2	T2231	I2234V	2234	Missense	distal	3	no	12.458	13.735	EPSD	TCGA;COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	P46013	MKI67	P24941	CDK2	T2259	G2263W	2263	Missense	distal	4	no	14.371	14.011	EPSD	TCGA;COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	P46013	MKI67	P24941	CDK2	T2259	S2261L	2261	Missense	proximal	2	no	14.371	14.198	EPSD	TCGA;COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	P46013	MKI67	P24941	CDK2	T2259	A2265V	2265	Missense	distal	6	no	14.371	14.374	EPSD	TCGA	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	P46013	MKI67	P24941	CDK2	T2259	R2258Q	2258	Missense	proximal	-1	no	14.371	13.493	EPSD	TCGA;GDSC;CCLE	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	P46013	MKI67	P24941	CDK2	T2268	G2263W	2263	Missense	distal	-5	no	11.937	11.992	EPSD	TCGA;COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	P46013	MKI67	P24941	CDK2	T2268	S2261L	2261	Missense	distal	-7	no	11.937	12.123	EPSD	TCGA;COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	P46013	MKI67	P24941	CDK2	T2268	A2265V	2265	Missense	distal	-3	no	11.937	12.138	EPSD	TCGA	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	P46013	MKI67	P24941	CDK2	T2285	L2290F	2290	Missense	distal	5	no	11.870	12.048	EPSD	TCGA;COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	P46013	MKI67	P24941	CDK2	T2305	A2310S	2310	Missense	distal	5	no	14.253	14.142	EPSD	TCGA;COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	P46013	MKI67	P24941	CDK2	T2305	P2306H	2306	Missense	proximal	1	no	14.253	7.495	EPSD	TCGA;COSMIC	8.148	Loss
CMGC_CDK_CDK2_CDK2_ST	P46013	MKI67	P24941	CDK2	T2325	T2332M	2332	Missense	distal	7	no	12.538	13.387	EPSD	TCGA;COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	P46013	MKI67	P24941	CDK2	T2325	G2318C	2318	Missense	distal	-7	no	12.538	12.485	EPSD	TCGA;COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	P46013	MKI67	P24941	CDK2	T2333	T2332M	2332	Missense	proximal	-1	no	8.966	10.279	EPSD	TCGA;COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	P46013	MKI67	P24941	CDK2	S2344	K2343T	2343	Missense	proximal	-1	no	12.666	12.503	EPSD	TCGA;ICGC;COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	P46013	MKI67	P24941	CDK2	T2352	R2359W	2359	Missense	distal	7	no	16.005	16.405	EPSD	TCGA;COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	P46013	MKI67	P24941	CDK2	T2352	K2357N	2357	Missense	distal	5	no	16.005	16.162	EPSD	TCGA	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	P46013	MKI67	P24941	CDK2	T2380	G2384D	2384	Missense	distal	4	no	12.939	12.994	EPSD	TCGA;COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	P46013	MKI67	P24941	CDK2	T2380	R2377K	2377	Missense	distal	-3	no	12.939	12.710	EPSD	TCGA;COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	P46013	MKI67	P24941	CDK2	T2380	G2384V	2384	Missense	distal	4	no	12.939	13.286	EPSD	TCGA;COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	P46013	MKI67	P24941	CDK2	T2380	L2374V	2374	Missense	distal	-6	no	12.939	12.941	EPSD	TCGA;COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	P46013	MKI67	P24941	CDK2	T2380	R2379Q	2379	Missense	proximal	-1	no	12.939	12.061	EPSD	TCGA;COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	P46013	MKI67	P24941	CDK2	T2389	G2384D	2384	Missense	distal	-5	no	11.306	11.284	EPSD	TCGA;COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	P46013	MKI67	P24941	CDK2	T2389	G2384V	2384	Missense	distal	-5	no	11.306	11.257	EPSD	TCGA;COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	P46013	MKI67	P24941	CDK2	S2395	I2400V	2400	Missense	distal	5	no	9.592	9.466	EPSD	TCGA	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	P46013	MKI67	P24941	CDK2	T2406	L2411P	2411	Missense	distal	5	no	12.686	12.646	EPSD	TCGA;COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	P46013	MKI67	P24941	CDK2	T2406	I2400V	2400	Missense	distal	-6	no	12.686	12.685	EPSD	TCGA	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	P46013	MKI67	P24941	CDK2	T2426	E2432Q	2432	Missense	distal	6	no	12.768	12.776	EPSD	TCGA;COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	P46013	MKI67	P24941	CDK2	T2426	Q2423H	2423	Missense	distal	-3	no	12.768	12.856	EPSD	TCGA;COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	P46013	MKI67	P24941	CDK2	T2426	E2429D	2429	Missense	distal	3	no	12.768	10.332	EPSD	TCGA	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	P46013	MKI67	P24941	CDK2	T2455	T2455N	2455	Missense	central	0	yes	9.096	0.000	EPSD	TCGA;COSMIC	8.148	Loss
CMGC_CDK_CDK2_CDK2_ST	P46013	MKI67	P24941	CDK2	T2455	E2461K	2461	Missense	distal	6	no	9.096	9.107	EPSD	TCGA;COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	P46013	MKI67	P24941	CDK2	S2466	F2472L	2472	Missense	distal	6	no	13.789	13.808	EPSD	TCGA;COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	P46013	MKI67	P24941	CDK2	S2466	S2463F	2463	Missense	distal	-3	no	13.789	13.880	EPSD	TCGA;COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	P46013	MKI67	P24941	CDK2	S2466	E2461K	2461	Missense	distal	-5	no	13.789	13.754	EPSD	TCGA;COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	P46013	MKI67	P24941	CDK2	S2466	K2473E	2473	Missense	distal	7	no	13.789	14.119	EPSD	TCGA;COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	P46013	MKI67	P24941	CDK2	S2528	F2525C	2525	Missense	distal	-3	no	12.355	12.271	EPSD	TCGA;COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	P46013	MKI67	P24941	CDK2	S2528	K2523N	2523	Missense	distal	-5	no	12.355	12.371	EPSD	TCGA;COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	P46013	MKI67	P24941	CDK2	T2540	R2543S	2543	Missense	distal	3	no	8.151	6.467	EPSD	TCGA;COSMIC	8.148	Loss
CMGC_CDK_CDK2_CDK2_ST	P46013	MKI67	P24941	CDK2	T2540	R2547I	2547	Missense	distal	7	no	8.151	7.718	EPSD	TCGA;COSMIC	8.148	Loss
CMGC_CDK_CDK2_CDK2_ST	P46013	MKI67	P24941	CDK2	S2588	K2583Q	2583	Missense	distal	-5	no	14.167	14.164	EPSD	TCGA;COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	P46013	MKI67	P24941	CDK2	T2630	T2623S	2623	Missense	distal	-7	no	9.481	9.303	EPSD	TCGA;COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	P46013	MKI67	P24941	CDK2	T2630	T2623M	2623	Missense	distal	-7	no	9.481	9.984	EPSD	TCGA;COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	P46013	MKI67	P24941	CDK2	T2630	H2633D	2633	Missense	distal	3	no	9.481	6.645	EPSD	TCGA;COSMIC	8.148	Loss
CMGC_CDK_CDK2_CDK2_ST	P46013	MKI67	P24941	CDK2	T2630	H2631Y	2631	Missense	proximal	1	no	9.481	0.740	EPSD	TCGA	8.148	Loss
CMGC_CDK_CDK2_CDK2_ST	P46013	MKI67	P24941	CDK2	S2708	E2707K	2707	Missense	proximal	-1	no	15.143	14.258	EPSD	TCGA;COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	P46013	MKI67	P24941	CDK2	S2708	K2703T	2703	Missense	distal	-5	no	15.143	15.139	EPSD	TCGA;COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	P46013	MKI67	P24941	CDK2	T2816	T2820I	2820	Missense	distal	4	no	9.032	8.721	EPSD	TCGA;COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	P46013	MKI67	P24941	CDK2	T2816	T2820A	2820	Missense	distal	4	no	9.032	8.789	EPSD	TCGA;COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	P46013	MKI67	P24941	CDK2	T2816	T2816A	2816	Missense	central	0	yes	9.032	0.000	EPSD	TCGA;COSMIC	8.148	Loss
CMGC_CDK_CDK2_CDK2_ST	P46013	MKI67	P24941	CDK2	S2828	E2832A	2832	Missense	distal	4	no	11.483	11.506	EPSD	TCGA;COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	P46013	MKI67	P24941	CDK2	S2828	D2833Y	2833	Missense	distal	5	no	11.483	11.383	EPSD	TCGA;COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	P46013	MKI67	P24941	CDK2	S2983	N2988S	2988	Missense	distal	5	no	9.209	9.005	EPSD	TCGA	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	P46013	MKI67	P24941	CDK2	S2983	S2990F	2990	Missense	distal	7	no	9.209	10.062	EPSD	TCGA;COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	P46013	MKI67	P24941	CDK2	T3007	V3006I	3006	Missense	proximal	-1	no	9.482	9.508	EPSD	TCGA;COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	P46013	MKI67	P24941	CDK2	S3128	E3121K	3121	Missense	distal	-7	no	12.515	12.378	EPSD	TCGA;COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	Q9NS91	RAD18	P24941	CDK2	S99	P100L	100	Missense	proximal	1	no	17.114	7.293	PhosphoSitePlus	TCGA;ICGC;COSMIC	8.148	Loss
CMGC_CDK_CDK2_CDK2_ST	Q9NS91	RAD18	P24941	CDK2	S103	K110N	110	Missense	distal	7	no	12.281	12.474	EPSD	TCGA;ICGC;COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	Q9NS91	RAD18	P24941	CDK2	S103	P100L	100	Missense	distal	-3	no	12.281	12.210	EPSD	TCGA;ICGC;COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	Q9NS91	RAD18	P24941	CDK2	T118	V120L	120	Missense	proximal	2	no	13.363	13.134	EPSD	TCGA	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	Q9NS91	RAD18	P24941	CDK2	S158	S155R	155	Missense	distal	-3	no	16.223	16.317	EPSD	TCGA;ICGC;COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	Q9NS91	RAD18	P24941	CDK2	S380	S380C	380	Missense	central	0	yes	8.840	0.000	EPSD	TCGA;ICGC;COSMIC	8.148	Loss
CMGC_CDK_CDK2_CDK2_ST	Q9NS91	RAD18	P24941	CDK2	S409	E412K	412	Missense	distal	3	no	17.115	19.201	EPSD	TCGA;ICGC;COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	Q9NS91	RAD18	P24941	CDK2	S471	L465I	465	Missense	distal	-6	no	15.137	15.139	EPSD	TCGA;ICGC;COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	Q9NS91	RAD18	P24941	CDK2	S471	R477H	477	Missense	distal	6	no	15.137	15.148	EPSD	TCGA;ICGC;COSMIC;GDSC;CCLE	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	P26358	DNMT1	P24941	CDK2	S115	R114I	114	Missense	proximal	-1	no	8.525	7.938	EPSD	TCGA;ICGC;COSMIC	8.148	Loss
CMGC_CDK_CDK2_CDK2_ST	P26358	DNMT1	P24941	CDK2	S127	D124H	124	Missense	distal	-3	no	14.636	14.717	EPSD	TCGA;ICGC;COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	P26358	DNMT1	P24941	CDK2	S714	M712I	712	Missense	proximal	-2	no	16.063	17.994	EPSD	TCGA;ICGC;COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	Q2NL82	TSR1	P24941	CDK2	T490	P491S	491	Missense	proximal	1	no	15.273	4.008	PhosphoSitePlus	TCGA;ICGC;COSMIC	8.148	Loss
CMGC_CDK_CDK2_CDK2_ST	Q2NL82	TSR1	P24941	CDK2	S512	T511I	511	Missense	proximal	-1	no	12.985	13.231	EPSD	TCGA;ICGC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	Q2NL82	TSR1	P24941	CDK2	S512	S512Y	512	Missense	central	0	yes	12.985	0.000	EPSD	TCGA;ICGC;COSMIC	8.148	Loss
CMGC_CDK_CDK2_CDK2_ST	Q2NL82	TSR1	P24941	CDK2	T577	P578L	578	Missense	proximal	1	no	11.959	2.138	EPSD	TCGA;ICGC;COSMIC	8.148	Loss
CMGC_CDK_CDK2_CDK2_ST	Q2NL82	TSR1	P24941	CDK2	S626	T633S	633	Missense	distal	7	no	12.660	12.812	EPSD	TCGA;ICGC;COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	Q9P2B4	CTTNBP2NL	P24941	CDK2	T340	Y345C	345	Missense	distal	5	no	10.277	10.437	EPSD	TCGA	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	Q9P2B4	CTTNBP2NL	P24941	CDK2	T340	P341T	341	Missense	proximal	1	no	10.277	0.319	EPSD	TCGA;ICGC;COSMIC	8.148	Loss
CMGC_CDK_CDK2_CDK2_ST	Q9P2B4	CTTNBP2NL	P24941	CDK2	S430	L437F	437	Missense	distal	7	no	13.445	14.116	EPSD	TCGA;ICGC;COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	Q9P2B4	CTTNBP2NL	P24941	CDK2	S430	R436H	436	Missense	distal	6	no	13.445	13.456	EPSD	TCGA;ICGC;COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	Q9P2B4	CTTNBP2NL	P24941	CDK2	S430	P427S	427	Missense	distal	-3	no	13.445	13.540	EPSD	TCGA;ICGC;COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	Q9P2B4	CTTNBP2NL	P24941	CDK2	S430	K435E	435	Missense	distal	5	no	13.445	13.578	EPSD	TCGA;ICGC;COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	Q9P2B4	CTTNBP2NL	P24941	CDK2	S430	S430L	430	Missense	central	0	yes	13.445	0.000	EPSD	TCGA;ICGC;COSMIC	8.148	Loss
CMGC_CDK_CDK2_CDK2_ST	Q9P2B4	CTTNBP2NL	P24941	CDK2	S430	P431L	431	Missense	proximal	1	no	13.445	3.624	EPSD	TCGA;ICGC;COSMIC	8.148	Loss
CMGC_CDK_CDK2_CDK2_ST	Q9P2B4	CTTNBP2NL	P24941	CDK2	S444	G446D	446	Missense	proximal	2	no	13.640	13.519	EPSD	TCGA	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	Q9P2B4	CTTNBP2NL	P24941	CDK2	S444	L437F	437	Missense	distal	-7	no	13.640	14.006	EPSD	TCGA;ICGC;COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	Q9P2B4	CTTNBP2NL	P24941	CDK2	S481	P482S	482	Missense	proximal	1	no	15.038	3.772	EPSD	TCGA;ICGC;COSMIC	8.148	Loss
CMGC_CDK_CDK2_CDK2_ST	Q9P2B4	CTTNBP2NL	P24941	CDK2	S481	L479R	479	Missense	proximal	-2	no	15.038	14.027	EPSD	TCGA;ICGC;COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	Q9P2B4	CTTNBP2NL	P24941	CDK2	S488	P482S	482	Missense	distal	-6	no	13.683	13.682	EPSD	TCGA;ICGC;COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	Q9P2B4	CTTNBP2NL	P24941	CDK2	S523	P518S	518	Missense	distal	-5	no	16.396	16.351	EPSD	TCGA;ICGC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	Q9P2B4	CTTNBP2NL	P24941	CDK2	S523	P528L	528	Missense	distal	5	no	16.396	16.436	EPSD	TCGA;ICGC;COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	Q9P2B4	CTTNBP2NL	P24941	CDK2	S527	P528L	528	Missense	proximal	1	no	13.558	3.737	EPSD	TCGA;ICGC;COSMIC	8.148	Loss
CMGC_CDK_CDK2_CDK2_ST	Q9P2B4	CTTNBP2NL	P24941	CDK2	S549	H548R	548	Missense	proximal	-1	no	13.188	13.639	EPSD	TCGA;ICGC;COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	Q9P2B4	CTTNBP2NL	P24941	CDK2	T551	H548R	548	Missense	distal	-3	no	16.693	16.736	EPSD	TCGA;ICGC;COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	Q9P2B4	CTTNBP2NL	P24941	CDK2	S557	P561S	561	Missense	distal	4	no	12.412	12.426	EPSD	TCGA;ICGC;COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	Q9P2B4	CTTNBP2NL	P24941	CDK2	S557	P561L	561	Missense	distal	4	no	12.412	12.524	EPSD	TCGA;ICGC;COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	Q9P2B4	CTTNBP2NL	P24941	CDK2	S560	P561S	561	Missense	proximal	1	no	16.512	5.247	EPSD	TCGA;ICGC;COSMIC	8.148	Loss
CMGC_CDK_CDK2_CDK2_ST	Q9P2B4	CTTNBP2NL	P24941	CDK2	S560	P561L	561	Missense	proximal	1	no	16.512	6.691	EPSD	TCGA;ICGC;COSMIC	8.148	Loss
CMGC_CDK_CDK2_CDK2_ST	Q9P2B4	CTTNBP2NL	P24941	CDK2	S563	P561S	561	Missense	proximal	-2	no	14.208	13.557	PhosphoSitePlus	TCGA;ICGC;COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	Q9P2B4	CTTNBP2NL	P24941	CDK2	S563	P561L	561	Missense	proximal	-2	no	14.208	13.983	PhosphoSitePlus	TCGA;ICGC;COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	Q9P2B4	CTTNBP2NL	P24941	CDK2	S568	E575Q	575	Missense	distal	7	no	12.058	11.859	EPSD	TCGA;ICGC;COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	Q9P2B4	CTTNBP2NL	P24941	CDK2	S568	P561S	561	Missense	distal	-7	no	12.058	11.878	EPSD	TCGA;ICGC;COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	Q9P2B4	CTTNBP2NL	P24941	CDK2	S568	P561L	561	Missense	distal	-7	no	12.058	12.064	EPSD	TCGA;ICGC;COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	Q9P2B4	CTTNBP2NL	P24941	CDK2	T590	P583S	583	Missense	distal	-7	no	12.047	11.867	EPSD	TCGA;ICGC;COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	Q9P2B4	CTTNBP2NL	P24941	CDK2	T590	P583L	583	Missense	distal	-7	no	12.047	12.052	EPSD	TCGA;ICGC;COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	Q9P2B4	CTTNBP2NL	P24941	CDK2	T590	P593L	593	Missense	distal	3	no	12.047	11.663	EPSD	TCGA;ICGC;COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	Q9P2B4	CTTNBP2NL	P24941	CDK2	T590	P584S	584	Missense	distal	-6	no	12.047	12.046	EPSD	TCGA;ICGC;COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	Q9P2B4	CTTNBP2NL	P24941	CDK2	S592	P598Q	598	Missense	distal	6	no	13.846	13.852	EPSD	TCGA;ICGC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	Q9P2B4	CTTNBP2NL	P24941	CDK2	S592	P593L	593	Missense	proximal	1	no	13.846	4.025	EPSD	TCGA;ICGC;COSMIC	8.148	Loss
CMGC_CDK_CDK2_CDK2_ST	Q9P2B4	CTTNBP2NL	P24941	CDK2	T597	H603Y	603	Missense	distal	6	no	13.582	13.579	EPSD	TCGA;ICGC;COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	Q9P2B4	CTTNBP2NL	P24941	CDK2	T597	P598Q	598	Missense	proximal	1	no	13.582	5.670	EPSD	TCGA;ICGC	8.148	Loss
CMGC_CDK_CDK2_CDK2_ST	Q9P2B4	CTTNBP2NL	P24941	CDK2	T597	T600I	600	Missense	distal	3	no	13.582	13.028	EPSD	TCGA;ICGC;COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	Q9P2B4	CTTNBP2NL	P24941	CDK2	T597	P593L	593	Missense	distal	-4	no	13.582	13.523	EPSD	TCGA;ICGC;COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	P17096	HMGA1	P24941	CDK2	T21	E22Q	22	Missense	proximal	1	no	7.347	8.601	EPSD	TCGA;ICGC;COSMIC	8.148	Gain
CMGC_CDK_CDK2_CDK2_ST	P17096	HMGA1	P24941	CDK2	S36	A40T	40	Missense	distal	4	no	14.045	14.287	PhosphoSitePlus	TCGA;ICGC;COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	P17096	HMGA1	P24941	CDK2	T53	K55N	55	Missense	proximal	2	no	16.127	16.198	EPSD	TCGA;ICGC;COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	P17096	HMGA1	P24941	CDK2	T53	R58W	58	Missense	distal	5	no	16.127	16.294	EPSD	TCGA;ICGC;COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	P38398	BRCA1	P24941	CDK2	S114	N113K	113	Missense	proximal	-1	no	14.472	14.445	EPSD	TCGA;ICGC;COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	P38398	BRCA1	P24941	CDK2	T208	T212A	212	Missense	distal	4	no	11.288	11.045	EPSD	TCGA;ICGC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	P38398	BRCA1	P24941	CDK2	S510	E515Q	515	Missense	distal	5	no	9.362	9.243	EPSD	TCGA;COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	P38398	BRCA1	P24941	CDK2	S510	E515V	515	Missense	distal	5	no	9.362	9.250	EPSD	TCGA;COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	P38398	BRCA1	P24941	CDK2	S510	E515K	515	Missense	distal	5	no	9.362	9.229	EPSD	TCGA;COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	P38398	BRCA1	P24941	CDK2	S510	H513Y	513	Missense	distal	3	no	9.362	7.595	EPSD	TCGA;COSMIC	8.148	Loss
CMGC_CDK_CDK2_CDK2_ST	P38398	BRCA1	P24941	CDK2	T528	V525A	525	Missense	distal	-3	no	13.750	13.549	EPSD	TCGA;COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	P38398	BRCA1	P24941	CDK2	T528	P529S	529	Missense	proximal	1	no	13.750	2.484	EPSD	TCGA;COSMIC	8.148	Loss
CMGC_CDK_CDK2_CDK2_ST	P38398	BRCA1	P24941	CDK2	T528	A524T	524	Missense	distal	-4	no	13.750	13.975	EPSD	TCGA;COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	P38398	BRCA1	P24941	CDK2	T676	E673K	673	Missense	distal	-3	no	9.846	9.631	EPSD	TCGA;COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	P38398	BRCA1	P24941	CDK2	T676	A675G	675	Missense	proximal	-1	no	9.846	11.165	EPSD	TCGA;COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	P38398	BRCA1	P24941	CDK2	S896	C903S	903	Missense	distal	7	no	16.991	16.198	EPSD	TCGA;COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	P38398	BRCA1	P24941	CDK2	S896	S889C	889	Missense	distal	-7	no	16.991	17.441	EPSD	TCGA;COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	P38398	BRCA1	P24941	CDK2	S896	E902K	902	Missense	distal	6	no	16.991	17.002	EPSD	TCGA;COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	P38398	BRCA1	P24941	CDK2	S896	V899L	899	Missense	distal	3	no	16.991	15.999	EPSD	TCGA;COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	P38398	BRCA1	P24941	CDK2	S896	K893N	893	Missense	distal	-3	no	16.991	17.052	EPSD	TCGA;COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	P38398	BRCA1	P24941	CDK2	T967	E962A	962	Missense	distal	-5	no	17.308	17.296	EPSD	TCGA;COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	P38398	BRCA1	P24941	CDK2	S1009	E1013Q	1013	Missense	distal	4	no	17.412	17.456	EPSD	TCGA	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	P38398	BRCA1	P24941	CDK2	S1009	N1002K	1002	Missense	distal	-7	no	17.412	17.446	EPSD	TCGA	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	P38398	BRCA1	P24941	CDK2	S1497	G1492R	1492	Missense	distal	-5	no	14.361	14.328	PhosphoSitePlus	TCGA;COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	Q9H1E3	NUCKS1	P24941	CDK2	S50	R49G	49	Missense	proximal	-1	no	8.399	8.877	EPSD	TCGA;ICGC;COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	Q9H1E3	NUCKS1	P24941	CDK2	S61	E59K	59	Missense	proximal	-2	no	8.120	8.721	EPSD	TCGA;ICGC;COSMIC	8.148	Gain
CMGC_CDK_CDK2_CDK2_ST	Q9H1E3	NUCKS1	P24941	CDK2	S148	S149L	149	Missense	proximal	1	no	7.108	8.553	EPSD	TCGA;ICGC;COSMIC;GDSC;CCLE	8.148	Gain
CMGC_CDK_CDK2_CDK2_ST	Q9H1E3	NUCKS1	P24941	CDK2	T179	P182L	182	Missense	distal	3	no	10.411	10.028	EPSD	TCGA;ICGC;COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	Q9H1E3	NUCKS1	P24941	CDK2	T179	P180S	180	Missense	proximal	1	no	10.411	-0.855	EPSD	TCGA;ICGC	8.148	Loss
CMGC_CDK_CDK2_CDK2_ST	Q9H1E3	NUCKS1	P24941	CDK2	S181	P182L	182	Missense	proximal	1	no	16.204	6.383	PhosphoSitePlus	TCGA;ICGC;COSMIC	8.148	Loss
CMGC_CDK_CDK2_CDK2_ST	Q9H1E3	NUCKS1	P24941	CDK2	S181	P180S	180	Missense	proximal	-1	no	16.204	15.733	PhosphoSitePlus	TCGA;ICGC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	Q9H1E3	NUCKS1	P24941	CDK2	T202	E208K	208	Missense	distal	6	no	11.962	11.973	EPSD	TCGA;ICGC;COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	Q9H1E3	NUCKS1	P24941	CDK2	T202	K201N	201	Missense	proximal	-1	no	11.962	11.988	EPSD	TCGA;ICGC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	Q9H1E3	NUCKS1	P24941	CDK2	S204	E208K	208	Missense	distal	4	no	14.862	15.247	EPSD	TCGA;ICGC;COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	Q9H1E3	NUCKS1	P24941	CDK2	S204	K201N	201	Missense	distal	-3	no	14.862	14.923	EPSD	TCGA;ICGC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	Q9H1E3	NUCKS1	P24941	CDK2	S214	P212L	212	Missense	proximal	-2	no	15.974	15.750	EPSD	TCGA;ICGC;COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	Q9H1E3	NUCKS1	P24941	CDK2	S214	E208K	208	Missense	distal	-6	no	15.974	15.972	EPSD	TCGA;ICGC;COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	Q9H1E3	NUCKS1	P24941	CDK2	S214	K218R	218	Missense	distal	4	no	15.974	15.453	EPSD	TCGA;ICGC;COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	Q9H1E3	NUCKS1	P24941	CDK2	S223	K218R	218	Missense	distal	-5	no	15.342	15.386	EPSD	TCGA;ICGC;COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	Q9H1E3	NUCKS1	P24941	CDK2	S223	E227K	227	Missense	distal	4	no	15.342	15.727	EPSD	TCGA;ICGC;COSMIC;GDSC;CCLE	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	Q9H1E3	NUCKS1	P24941	CDK2	S229	E227K	227	Missense	proximal	-2	no	8.143	8.744	EPSD	TCGA;ICGC;COSMIC;GDSC;CCLE	8.148	Gain
CMGC_CDK_CDK2_CDK2_ST	Q9H3D4	TP63	P24941	CDK2	S51	I58T	58	Missense	distal	7	no	15.306	14.945	EPSD	TCGA;ICGC;COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	Q9H3D4	TP63	P24941	CDK2	S51	E53Q	53	Missense	proximal	2	no	15.306	15.269	EPSD	TCGA;ICGC;COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	Q9H3D4	TP63	P24941	CDK2	S160	P166L	166	Missense	distal	6	no	12.081	12.082	EPSD	TCGA;ICGC;COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	Q9H3D4	TP63	P24941	CDK2	S160	A164T	164	Missense	distal	4	no	12.081	12.324	EPSD	TCGA;COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	Q9H3D4	TP63	P24941	CDK2	S160	A164V	164	Missense	distal	4	no	12.081	12.268	EPSD	TCGA;ICGC;COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	Q9H3D4	TP63	P24941	CDK2	S160	P163L	163	Missense	distal	3	no	12.081	11.698	EPSD	TCGA;ICGC;COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	Q9H3D4	TP63	P24941	CDK2	S160	S153R	153	Missense	distal	-7	no	12.081	12.605	EPSD	TCGA;ICGC;COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	Q9H3D4	TP63	P24941	CDK2	S160	D157Y	157	Missense	distal	-3	no	12.081	12.131	EPSD	TCGA;ICGC;COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	Q9H3D4	TP63	P24941	CDK2	S162	P166L	166	Missense	distal	4	no	10.982	11.094	EPSD	TCGA;ICGC;COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	Q9H3D4	TP63	P24941	CDK2	S162	A164T	164	Missense	proximal	2	no	10.982	10.780	EPSD	TCGA;COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	Q9H3D4	TP63	P24941	CDK2	S162	A164V	164	Missense	proximal	2	no	10.982	11.080	EPSD	TCGA;ICGC;COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	Q9H3D4	TP63	P24941	CDK2	S162	P163L	163	Missense	proximal	1	no	10.982	1.162	EPSD	TCGA;ICGC;COSMIC	8.148	Loss
CMGC_CDK_CDK2_CDK2_ST	Q9H3D4	TP63	P24941	CDK2	S162	D157Y	157	Missense	distal	-5	no	10.982	10.949	EPSD	TCGA;ICGC;COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	Q9H3D4	TP63	P24941	CDK2	S395	P396T	396	Missense	proximal	1	no	10.892	0.935	EPSD	TCGA;COSMIC	8.148	Loss
CMGC_CDK_CDK2_CDK2_ST	Q9H3D4	TP63	P24941	CDK2	S395	T388I	388	Missense	distal	-7	no	10.892	11.089	EPSD	TCGA;ICGC;COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	Q9H3D4	TP63	P24941	CDK2	S395	D398N	398	Missense	distal	3	no	10.892	12.143	EPSD	TCGA;ICGC;COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	Q9H3D4	TP63	P24941	CDK2	S395	S389F	389	Missense	distal	-6	no	10.892	10.897	EPSD	TCGA;ICGC;COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	Q9H3D4	TP63	P24941	CDK2	S395	D397G	397	Missense	proximal	2	no	10.892	11.013	EPSD	TCGA;COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	Q9H3D4	TP63	P24941	CDK2	S395	R393Q	393	Missense	proximal	-2	no	10.892	11.561	EPSD	TCGA;COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	Q9H3D4	TP63	P24941	CDK2	S395	K391N	391	Missense	distal	-4	no	10.892	11.111	EPSD	TCGA;COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	Q9H3D4	TP63	P24941	CDK2	S455	S458L	458	Missense	distal	3	no	13.585	13.168	EPSD	TCGA;COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	Q9H3D4	TP63	P24941	CDK2	S455	P456L	456	Missense	proximal	1	no	13.585	3.764	EPSD	TCGA;COSMIC	8.148	Loss
CMGC_CDK_CDK2_CDK2_ST	Q9H3D4	TP63	P24941	CDK2	S463	P464L	464	Missense	proximal	1	no	11.144	1.323	EPSD	TCGA;COSMIC	8.148	Loss
CMGC_CDK_CDK2_CDK2_ST	Q9H3D4	TP63	P24941	CDK2	S463	M469I	469	Missense	distal	6	no	11.144	11.163	EPSD	TCGA;COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	Q9H3D4	TP63	P24941	CDK2	S463	N467S	467	Missense	distal	4	no	11.144	11.178	EPSD	TCGA;COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	Q9H3D4	TP63	P24941	CDK2	S463	S458L	458	Missense	distal	-5	no	11.144	11.200	EPSD	TCGA;COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	Q9H3D4	TP63	P24941	CDK2	S463	P456L	456	Missense	distal	-7	no	11.144	11.150	EPSD	TCGA;COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	Q9H3D4	TP63	P24941	CDK2	T491	P492A	492	Missense	proximal	1	no	13.063	-1.341	PhosphoSitePlus	TCGA;COSMIC	8.148	Loss
CMGC_CDK_CDK2_CDK2_ST	Q9H3D4	TP63	P24941	CDK2	T491	P492S	492	Missense	proximal	1	no	13.063	1.797	PhosphoSitePlus	TCGA;COSMIC	8.148	Loss
CMGC_CDK_CDK2_CDK2_ST	Q9H3D4	TP63	P24941	CDK2	T491	R487C	487	Missense	distal	-4	no	13.063	12.554	PhosphoSitePlus	TCGA;COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	Q9H3D4	TP63	P24941	CDK2	T491	P496S	496	Missense	distal	5	no	13.063	12.962	PhosphoSitePlus	TCGA;COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	Q9H3D4	TP63	P24941	CDK2	T491	R487S	487	Missense	distal	-4	no	13.063	13.660	PhosphoSitePlus	TCGA	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	Q9H3D4	TP63	P24941	CDK2	T491	A489T	489	Missense	proximal	-2	no	13.063	13.013	PhosphoSitePlus	TCGA;COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	Q9H3D4	TP63	P24941	CDK2	T491	R487H	487	Missense	distal	-4	no	13.063	12.702	PhosphoSitePlus	TCGA;COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	Q9H3D4	TP63	P24941	CDK2	S612	E609K	609	Missense	distal	-3	no	13.702	13.487	EPSD	TCGA;COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	Q9H3D4	TP63	P24941	CDK2	S612	H615Y	615	Missense	distal	3	no	13.702	11.935	EPSD	TCGA;COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	Q9H3D4	TP63	P24941	CDK2	S612	F610L	610	Missense	proximal	-2	no	13.702	14.591	EPSD	TCGA;COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	Q9H3D4	TP63	P24941	CDK2	T619	H615Y	615	Missense	distal	-4	no	14.501	15.570	EPSD	TCGA;COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	O75152	ZC3H11A	P24941	CDK2	S108	P109L	109	Missense	proximal	1	no	14.733	4.913	EPSD	TCGA;ICGC;COSMIC	8.148	Loss
CMGC_CDK_CDK2_CDK2_ST	O75152	ZC3H11A	P24941	CDK2	S108	V101L	101	Missense	distal	-7	no	14.733	14.719	EPSD	TCGA;ICGC;COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	O75152	ZC3H11A	P24941	CDK2	S132	N130S	130	Missense	proximal	-2	no	13.991	14.682	EPSD	TCGA;ICGC;COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	O75152	ZC3H11A	P24941	CDK2	S132	V138I	138	Missense	distal	6	no	13.991	13.992	EPSD	TCGA;ICGC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	O75152	ZC3H11A	P24941	CDK2	S132	Q128H	128	Missense	distal	-4	no	13.991	13.605	EPSD	TCGA;ICGC;COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	O75152	ZC3H11A	P24941	CDK2	S132	P131S	131	Missense	proximal	-1	no	13.991	13.519	EPSD	TCGA;ICGC;COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	O75152	ZC3H11A	P24941	CDK2	S132	M139V	139	Missense	distal	7	no	13.991	13.704	EPSD	TCGA;ICGC;COSMIC;CCLE	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	O75152	ZC3H11A	P24941	CDK2	S149	E145K	145	Missense	distal	-4	no	15.255	14.944	EPSD	TCGA;ICGC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	O75152	ZC3H11A	P24941	CDK2	T179	T179I	179	Missense	central	0	yes	11.614	0.000	EPSD	TCGA;ICGC;COSMIC	8.148	Loss
CMGC_CDK_CDK2_CDK2_ST	O75152	ZC3H11A	P24941	CDK2	T179	E172Q	172	Missense	distal	-7	no	11.614	11.481	EPSD	TCGA;ICGC;COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	O75152	ZC3H11A	P24941	CDK2	T185	T179I	179	Missense	distal	-6	no	13.808	13.810	EPSD	TCGA;ICGC;COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	O75152	ZC3H11A	P24941	CDK2	T321	K324E	324	Missense	distal	3	no	17.644	15.559	PhosphoSitePlus	TCGA;ICGC;COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	O75152	ZC3H11A	P24941	CDK2	T321	K320N	320	Missense	proximal	-1	no	17.644	17.671	PhosphoSitePlus	TCGA;ICGC;COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	O75152	ZC3H11A	P24941	CDK2	T502	R507P	507	Missense	distal	5	no	11.820	11.714	EPSD	TCGA;ICGC;COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	O75152	ZC3H11A	P24941	CDK2	T502	G504V	504	Missense	proximal	2	no	11.820	11.825	EPSD	TCGA;ICGC;COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	O75152	ZC3H11A	P24941	CDK2	T579	R582Q	582	Missense	distal	3	no	13.273	11.530	EPSD	TCGA;ICGC;COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	O75152	ZC3H11A	P24941	CDK2	T579	V585A	585	Missense	distal	6	no	13.273	13.270	EPSD	TCGA;ICGC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	O75152	ZC3H11A	P24941	CDK2	T579	R582W	582	Missense	distal	3	no	13.273	10.633	EPSD	TCGA;ICGC;COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	O75152	ZC3H11A	P24941	CDK2	S663	P664S	664	Missense	proximal	1	no	11.007	-0.259	EPSD	TCGA;ICGC;COSMIC	8.148	Loss
CMGC_CDK_CDK2_CDK2_ST	O75152	ZC3H11A	P24941	CDK2	S738	S733P	733	Missense	distal	-5	no	13.445	13.489	EPSD	TCGA;ICGC;COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	O75152	ZC3H11A	P24941	CDK2	S738	V742A	742	Missense	distal	4	no	13.445	13.258	EPSD	TCGA;ICGC;COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	O75152	ZC3H11A	P24941	CDK2	S781	S781L	781	Missense	central	0	yes	10.570	0.000	EPSD	TCGA;ICGC;COSMIC	8.148	Loss
CMGC_CDK_CDK2_CDK2_ST	O75152	ZC3H11A	P24941	CDK2	S781	I777M	777	Missense	distal	-4	no	10.570	9.973	EPSD	TCGA;ICGC;COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	O75152	ZC3H11A	P24941	CDK2	S781	I777T	777	Missense	distal	-4	no	10.570	10.887	EPSD	TCGA;ICGC;COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	Q8IXJ6	SIRT2	P24941	CDK2	S25	A31V	31	Missense	distal	6	no	9.646	9.649	EPSD	TCGA;ICGC;COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	Q8IXJ6	SIRT2	P24941	CDK2	S193	G188S	188	Missense	distal	-5	no	10.259	10.135	EPSD	TCGA;ICGC;COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	Q8IXJ6	SIRT2	P24941	CDK2	S193	A186V	186	Missense	distal	-7	no	10.259	10.114	EPSD	TCGA;ICGC;COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	Q8IXJ6	SIRT2	P24941	CDK2	S368	S366L	366	Missense	proximal	-2	no	15.904	16.330	PhosphoSitePlus;EPSD	TCGA;COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	Q8IXJ6	SIRT2	P24941	CDK2	S368	S366T	366	Missense	proximal	-2	no	15.904	16.521	PhosphoSitePlus;EPSD	TCGA;ICGC;COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	Q8IXJ6	SIRT2	P24941	CDK2	S372	S366L	366	Missense	distal	-6	no	14.855	14.856	EPSD	TCGA;COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	P55795	HNRNPH2	P24941	CDK2	S104	G111D	111	Missense	distal	7	no	14.520	14.537	PhosphoSitePlus	TCGA	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	P55795	HNRNPH2	P24941	CDK2	S104	S104N	104	Missense	central	0	yes	14.520	0.000	PhosphoSitePlus	TCGA;ICGC;COSMIC	8.148	Loss
CMGC_CDK_CDK2_CDK2_ST	P55795	HNRNPH2	P24941	CDK2	S104	D110N	110	Missense	distal	6	no	14.520	14.539	PhosphoSitePlus	TCGA;ICGC;COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	P55795	HNRNPH2	P24941	CDK2	S272	G277R	277	Missense	distal	5	no	8.567	8.547	EPSD	TCGA;ICGC;COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	P55795	HNRNPH2	P24941	CDK2	S272	S269L	269	Missense	distal	-3	no	8.567	8.401	EPSD	TCGA;ICGC;COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	P55795	HNRNPH2	P24941	CDK2	S272	S272A	272	Missense	central	0	yes	8.567	0.000	EPSD	TCGA;ICGC;COSMIC	8.148	Loss
CMGC_CDK_CDK2_CDK2_ST	P55795	HNRNPH2	P24941	CDK2	S310	D304Y	304	Missense	distal	-6	no	14.756	14.757	EPSD	TCGA;ICGC;COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	Q9P270	SLAIN2	P24941	CDK2	S48	A52T	52	Missense	distal	4	no	16.198	16.441	PhosphoSitePlus	TCGA;ICGC;COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	Q9P270	SLAIN2	P24941	CDK2	S134	W130C	130	Missense	distal	-4	no	14.737	14.986	EPSD	TCGA;ICGC;COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	Q9P270	SLAIN2	P24941	CDK2	T140	M142L	142	Missense	proximal	2	no	12.481	12.163	EPSD	TCGA;ICGC;COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	Q9P270	SLAIN2	P24941	CDK2	T140	S145L	145	Missense	distal	5	no	12.481	12.622	EPSD	TCGA;ICGC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	Q9P270	SLAIN2	P24941	CDK2	S147	M142L	142	Missense	distal	-5	no	14.293	14.198	EPSD	TCGA;ICGC;COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	Q9P270	SLAIN2	P24941	CDK2	S147	S145L	145	Missense	proximal	-2	no	14.293	14.720	EPSD	TCGA;ICGC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	Q9P270	SLAIN2	P24941	CDK2	S160	P161S	161	Missense	proximal	1	no	14.890	3.624	EPSD	TCGA;ICGC;COSMIC	8.148	Loss
CMGC_CDK_CDK2_CDK2_ST	Q9P270	SLAIN2	P24941	CDK2	S198	A204T	204	Missense	distal	6	no	13.561	13.573	EPSD	TCGA;COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	Q9P270	SLAIN2	P24941	CDK2	S198	P199R	199	Missense	proximal	1	no	13.561	3.763	EPSD	TCGA;COSMIC	8.148	Loss
CMGC_CDK_CDK2_CDK2_ST	Q9P270	SLAIN2	P24941	CDK2	S201	S206R	206	Missense	distal	5	no	14.209	14.416	EPSD	TCGA;COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	Q9P270	SLAIN2	P24941	CDK2	S201	A204T	204	Missense	distal	3	no	14.209	14.607	EPSD	TCGA;COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	Q9P270	SLAIN2	P24941	CDK2	S201	P199R	199	Missense	proximal	-2	no	14.209	12.973	EPSD	TCGA;COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	Q9P270	SLAIN2	P24941	CDK2	S247	P245S	245	Missense	proximal	-2	no	15.152	14.501	EPSD	TCGA;COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	Q9P270	SLAIN2	P24941	CDK2	S315	T313N	313	Missense	proximal	-2	no	9.324	8.015	EPSD	TCGA;COSMIC	8.148	Loss
CMGC_CDK_CDK2_CDK2_ST	Q9P270	SLAIN2	P24941	CDK2	S315	R311W	311	Missense	distal	-4	no	9.324	8.567	EPSD	TCGA	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	Q9P270	SLAIN2	P24941	CDK2	S343	N340T	340	Missense	distal	-3	no	14.013	13.953	EPSD	TCGA;COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	Q9P270	SLAIN2	P24941	CDK2	S343	P350S	350	Missense	distal	7	no	14.013	13.861	EPSD	TCGA;COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	Q9P270	SLAIN2	P24941	CDK2	S345	S349L	349	Missense	distal	4	no	11.858	11.956	EPSD	TCGA;COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	Q9P270	SLAIN2	P24941	CDK2	S345	N340T	340	Missense	distal	-5	no	11.858	11.838	EPSD	TCGA;COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	Q9P270	SLAIN2	P24941	CDK2	S345	P350S	350	Missense	distal	5	no	11.858	11.757	EPSD	TCGA;COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	Q9P270	SLAIN2	P24941	CDK2	S345	P352L	352	Missense	distal	7	no	11.858	11.888	EPSD	TCGA;COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	Q9P270	SLAIN2	P24941	CDK2	S345	R351Q	351	Missense	distal	6	no	11.858	11.880	EPSD	TCGA;COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	Q9P270	SLAIN2	P24941	CDK2	S349	S349L	349	Missense	central	0	yes	14.807	0.000	EPSD	TCGA;COSMIC	8.148	Loss
CMGC_CDK_CDK2_CDK2_ST	Q9P270	SLAIN2	P24941	CDK2	S349	P350S	350	Missense	proximal	1	no	14.807	3.541	EPSD	TCGA;COSMIC	8.148	Loss
CMGC_CDK_CDK2_CDK2_ST	Q9P270	SLAIN2	P24941	CDK2	S349	P352L	352	Missense	distal	3	no	14.807	14.424	EPSD	TCGA;COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	Q9P270	SLAIN2	P24941	CDK2	S349	R351Q	351	Missense	proximal	2	no	14.807	14.707	EPSD	TCGA;COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	Q9P270	SLAIN2	P24941	CDK2	S353	S349L	349	Missense	distal	-4	no	11.669	11.256	EPSD	TCGA;COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	Q9P270	SLAIN2	P24941	CDK2	S353	P350S	350	Missense	distal	-3	no	11.669	11.764	EPSD	TCGA;COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	Q9P270	SLAIN2	P24941	CDK2	S353	P352L	352	Missense	proximal	-1	no	11.669	11.489	EPSD	TCGA;COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	Q9P270	SLAIN2	P24941	CDK2	S353	R351Q	351	Missense	proximal	-2	no	11.669	12.337	EPSD	TCGA;COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	Q9P270	SLAIN2	P24941	CDK2	S357	P350S	350	Missense	distal	-7	no	12.354	12.174	EPSD	TCGA;COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	Q9P270	SLAIN2	P24941	CDK2	S357	P352L	352	Missense	distal	-5	no	12.354	12.366	EPSD	TCGA;COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	Q9P270	SLAIN2	P24941	CDK2	S357	R351Q	351	Missense	distal	-6	no	12.354	12.355	EPSD	TCGA;COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	Q9P270	SLAIN2	P24941	CDK2	S357	S361L	361	Missense	distal	4	no	12.354	12.453	EPSD	TCGA;COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	Q9P270	SLAIN2	P24941	CDK2	S361	S361L	361	Missense	central	0	yes	13.096	0.000	EPSD	TCGA;COSMIC	8.148	Loss
CMGC_CDK_CDK2_CDK2_ST	Q9P270	SLAIN2	P24941	CDK2	S366	R369W	369	Missense	distal	3	no	17.857	15.217	EPSD	TCGA;COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	Q9P270	SLAIN2	P24941	CDK2	S366	E372K	372	Missense	distal	6	no	17.857	17.868	EPSD	TCGA;COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	Q9P270	SLAIN2	P24941	CDK2	S366	G370E	370	Missense	distal	4	no	17.857	17.994	EPSD	TCGA;COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	Q9P270	SLAIN2	P24941	CDK2	S366	S361L	361	Missense	distal	-5	no	17.857	17.913	EPSD	TCGA;COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	Q9P270	SLAIN2	P24941	CDK2	S377	E372K	372	Missense	distal	-5	no	15.717	15.683	EPSD	TCGA;COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	Q9P270	SLAIN2	P24941	CDK2	S377	V376E	376	Missense	proximal	-1	no	15.717	16.546	EPSD	TCGA;COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	Q9P270	SLAIN2	P24941	CDK2	S377	G370E	370	Missense	distal	-7	no	15.717	15.483	EPSD	TCGA;COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	Q9P270	SLAIN2	P24941	CDK2	S377	P380S	380	Missense	distal	3	no	15.717	15.752	EPSD	TCGA;COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	Q9P270	SLAIN2	P24941	CDK2	S456	R461H	461	Missense	distal	5	no	15.167	15.139	EPSD	TCGA;COSMIC;GDSC;CCLE	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	Q9P270	SLAIN2	P24941	CDK2	S456	P457L	457	Missense	proximal	1	no	15.167	5.346	EPSD	TCGA;COSMIC	8.148	Loss
CMGC_CDK_CDK2_CDK2_ST	Q9P270	SLAIN2	P24941	CDK2	S456	A453V	453	Missense	distal	-3	no	15.167	15.368	EPSD	TCGA;COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	Q9P270	SLAIN2	P24941	CDK2	S456	A453D	453	Missense	distal	-3	no	15.167	15.290	EPSD	TCGA	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	Q9P270	SLAIN2	P24941	CDK2	S462	P466S	466	Missense	distal	4	no	13.727	13.741	EPSD	TCGA;COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	Q9P270	SLAIN2	P24941	CDK2	S462	R461H	461	Missense	proximal	-1	no	13.727	13.276	EPSD	TCGA;COSMIC;GDSC;CCLE	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	Q9P270	SLAIN2	P24941	CDK2	S462	P457L	457	Missense	distal	-5	no	13.727	13.739	EPSD	TCGA;COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	Q9P270	SLAIN2	P24941	CDK2	S467	R472W	472	Missense	distal	5	no	13.708	13.874	EPSD	TCGA;COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	Q9P270	SLAIN2	P24941	CDK2	S467	P466S	466	Missense	proximal	-1	no	13.708	13.237	EPSD	TCGA;COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	Q9P270	SLAIN2	P24941	CDK2	S467	R461H	461	Missense	distal	-6	no	13.708	13.709	EPSD	TCGA;COSMIC;GDSC;CCLE	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	Q13309	SKP2	P24941	CDK2	S64	L59R	59	Missense	distal	-5	no	15.360	15.395	PhosphoSitePlus	TCGA;ICGC;COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	Q13309	SKP2	P24941	CDK2	S179	S179G	179	Missense	central	0	yes	17.503	0.000	EPSD	TCGA;COSMIC	8.148	Loss
CMGC_CDK_CDK2_CDK2_ST	Q13309	SKP2	P24941	CDK2	S179	V183A	183	Missense	distal	4	no	17.503	17.316	EPSD	TCGA;ICGC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	Q13309	SKP2	P24941	CDK2	S179	Q184K	184	Missense	distal	5	no	17.503	17.489	EPSD	TCGA;ICGC;COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	Q13309	SKP2	P24941	CDK2	S179	R182C	182	Missense	distal	3	no	17.503	11.139	EPSD	TCGA;ICGC;COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	Q13309	SKP2	P24941	CDK2	S179	A175T	175	Missense	distal	-4	no	17.503	17.729	EPSD	TCGA;ICGC;COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	Q13309	SKP2	P24941	CDK2	S179	V183I	183	Missense	distal	4	no	17.503	17.248	EPSD	TCGA;ICGC;COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	Q13309	SKP2	P24941	CDK2	S179	Q172R	172	Missense	distal	-7	no	17.503	17.890	EPSD	TCGA;ICGC;COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	P04637	TP53	P24941	CDK2	S33	P27S	27	Missense	distal	-6	no	15.549	15.548	EPSD	TCGA;ICGC;COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	P04637	TP53	P24941	CDK2	S46	D48N	48	Missense	proximal	2	no	14.212	14.144	EPSD	TCGA;ICGC;COSMIC;GDSC;CCLE	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	P04637	TP53	P24941	CDK2	T81	A79V	79	Missense	proximal	-2	no	14.045	13.380	EPSD	TCGA;ICGC;COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	P04637	TP53	P24941	CDK2	T81	P77L	77	Missense	distal	-4	no	14.045	13.987	EPSD	TCGA;ICGC;COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	P04637	TP53	P24941	CDK2	T81	P82L	82	Missense	proximal	1	no	14.045	4.225	EPSD	TCGA;ICGC;COSMIC	8.148	Loss
CMGC_CDK_CDK2_CDK2_ST	P04637	TP53	P24941	CDK2	T81	A74T	74	Missense	distal	-7	no	14.045	13.878	EPSD	TCGA;ICGC;COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	P04637	TP53	P24941	CDK2	S127	K132N	132	Missense	distal	5	no	15.119	15.276	EPSD	TCGA;ICGC;COSMIC;GDSC;CCLE	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	P04637	TP53	P24941	CDK2	S127	S121Y	121	Missense	distal	-6	no	15.119	15.120	EPSD	TCGA;ICGC;COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	P04637	TP53	P24941	CDK2	S127	M133K	133	Missense	distal	6	no	15.119	15.147	EPSD	TCGA;ICGC;COSMIC;CCLE	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	P04637	TP53	P24941	CDK2	S127	K132E	132	Missense	distal	5	no	15.119	15.253	EPSD	TCGA;ICGC;COSMIC;GDSC;CCLE	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	P04637	TP53	P24941	CDK2	S127	Y126C	126	Missense	proximal	-1	no	15.119	14.553	EPSD	TCGA;ICGC;COSMIC;GDSC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	P04637	TP53	P24941	CDK2	S127	S127P	127	Missense	central	0	yes	15.119	0.000	EPSD	TCGA;ICGC;COSMIC;GDSC;CCLE	8.148	Loss
CMGC_CDK_CDK2_CDK2_ST	P04637	TP53	P24941	CDK2	S127	Y126N	126	Missense	proximal	-1	no	15.119	14.607	EPSD	TCGA;ICGC;COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	P04637	TP53	P24941	CDK2	S127	L130V	130	Missense	distal	3	no	15.119	16.111	EPSD	TCGA;ICGC;COSMIC;GDSC;CCLE	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	P04637	TP53	P24941	CDK2	S127	K132T	132	Missense	distal	5	no	15.119	15.148	EPSD	TCGA;ICGC;COSMIC;GDSC;CCLE	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	P04637	TP53	P24941	CDK2	S127	S127Y	127	Missense	central	0	yes	15.119	0.000	EPSD	TCGA;ICGC;COSMIC	8.148	Loss
CMGC_CDK_CDK2_CDK2_ST	P04637	TP53	P24941	CDK2	S127	S127F	127	Missense	central	0	yes	15.119	0.000	EPSD	TCGA;ICGC;COSMIC;CCLE	8.148	Loss
CMGC_CDK_CDK2_CDK2_ST	P04637	TP53	P24941	CDK2	S127	M133R	133	Missense	distal	6	no	15.119	15.122	EPSD	TCGA;ICGC;COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	P04637	TP53	P24941	CDK2	S127	K132R	132	Missense	distal	5	no	15.119	15.280	EPSD	TCGA;ICGC;COSMIC;GDSC;CCLE	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	P04637	TP53	P24941	CDK2	S127	F134L	134	Missense	distal	7	no	15.119	14.448	EPSD	TCGA;ICGC;COSMIC;CCLE	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	P04637	TP53	P24941	CDK2	S127	Y126S	126	Missense	proximal	-1	no	15.119	14.209	EPSD	TCGA;ICGC;COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	P04637	TP53	P24941	CDK2	S127	L130P	130	Missense	distal	3	no	15.119	15.503	EPSD	TCGA;ICGC;COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	P04637	TP53	P24941	CDK2	S127	L130F	130	Missense	distal	3	no	15.119	15.462	EPSD	TCGA;ICGC;COSMIC;CCLE	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	P04637	TP53	P24941	CDK2	S127	F134V	134	Missense	distal	7	no	15.119	14.676	EPSD	TCGA;ICGC;COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	P04637	TP53	P24941	CDK2	S127	T125M	125	Missense	proximal	-2	no	15.119	13.068	EPSD	TCGA;ICGC;COSMIC;GDSC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	P04637	TP53	P24941	CDK2	S127	Y126D	126	Missense	proximal	-1	no	15.119	15.436	EPSD	TCGA;ICGC;COSMIC;GDSC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	P04637	TP53	P24941	CDK2	S127	K120E	120	Missense	distal	-7	no	15.119	15.257	EPSD	TCGA;ICGC;COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	P04637	TP53	P24941	CDK2	S127	N131S	131	Missense	distal	4	no	15.119	15.153	EPSD	TCGA;ICGC;COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	P04637	TP53	P24941	CDK2	S127	T125P	125	Missense	proximal	-2	no	15.119	15.153	EPSD	TCGA;ICGC;COSMIC;CCLE	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	P04637	TP53	P24941	CDK2	S127	S127C	127	Missense	central	0	yes	15.119	0.000	EPSD	TCGA;ICGC;COSMIC;CCLE	8.148	Loss
CMGC_CDK_CDK2_CDK2_ST	P04637	TP53	P24941	CDK2	S127	N131I	131	Missense	distal	4	no	15.119	15.111	EPSD	TCGA;ICGC;COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	P04637	TP53	P24941	CDK2	S127	Y126H	126	Missense	proximal	-1	no	15.119	14.800	EPSD	TCGA;ICGC;COSMIC;GDSC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	P04637	TP53	P24941	CDK2	S127	K132Q	132	Missense	distal	5	no	15.119	15.133	EPSD	TCGA;ICGC;COSMIC;GDSC;CCLE	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	P04637	TP53	P24941	CDK2	S127	L130R	130	Missense	distal	3	no	15.119	17.221	EPSD	TCGA;ICGC;COSMIC;CCLE	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	P04637	TP53	P24941	CDK2	T150	W146S	146	Missense	distal	-4	no	10.420	11.775	EPSD	TCGA;ICGC;COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	P04637	TP53	P24941	CDK2	T150	P152L	152	Missense	proximal	2	no	10.420	10.314	EPSD	TCGA;ICGC;COSMIC;GDSC;CCLE	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	P04637	TP53	P24941	CDK2	T150	D148N	148	Missense	proximal	-2	no	10.420	9.212	EPSD	TCGA;ICGC;COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	P04637	TP53	P24941	CDK2	T150	P151H	151	Missense	proximal	1	no	10.420	3.662	EPSD	TCGA;ICGC;COSMIC;GDSC;CCLE	8.148	Loss
CMGC_CDK_CDK2_CDK2_ST	P04637	TP53	P24941	CDK2	T150	P151A	151	Missense	proximal	1	no	10.420	-3.983	EPSD	TCGA;ICGC;COSMIC;CCLE	8.148	Loss
CMGC_CDK_CDK2_CDK2_ST	P04637	TP53	P24941	CDK2	T150	R156P	156	Missense	distal	6	no	10.420	10.437	EPSD	TCGA;ICGC;COSMIC;GDSC;CCLE	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	P04637	TP53	P24941	CDK2	T150	V143A	143	Missense	distal	-7	no	10.420	10.565	EPSD	TCGA;ICGC;COSMIC;GDSC;CCLE	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	P04637	TP53	P24941	CDK2	T150	P151S	151	Missense	proximal	1	no	10.420	-0.845	EPSD	TCGA;ICGC;COSMIC;GDSC;CCLE	8.148	Loss
CMGC_CDK_CDK2_CDK2_ST	P04637	TP53	P24941	CDK2	T150	V157F	157	Missense	distal	7	no	10.420	10.864	EPSD	TCGA;ICGC;COSMIC;GDSC;CCLE	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	P04637	TP53	P24941	CDK2	T150	V157G	157	Missense	distal	7	no	10.420	10.832	EPSD	TCGA;ICGC;COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	P04637	TP53	P24941	CDK2	T150	V157D	157	Missense	distal	7	no	10.420	10.848	EPSD	TCGA;ICGC;COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	P04637	TP53	P24941	CDK2	T150	L145R	145	Missense	distal	-5	no	10.420	10.455	EPSD	TCGA;ICGC;COSMIC;GDSC;CCLE	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	P04637	TP53	P24941	CDK2	T150	T155I	155	Missense	distal	5	no	10.420	10.539	EPSD	TCGA;ICGC;COSMIC;CCLE	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	P04637	TP53	P24941	CDK2	T150	V143M	143	Missense	distal	-7	no	10.420	10.902	EPSD	TCGA;ICGC;COSMIC;GDSC;CCLE	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	P04637	TP53	P24941	CDK2	T150	T155N	155	Missense	distal	5	no	10.420	10.549	EPSD	TCGA;ICGC;COSMIC;GDSC;CCLE	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	P04637	TP53	P24941	CDK2	T150	P152S	152	Missense	proximal	2	no	10.420	10.487	EPSD	TCGA;ICGC;COSMIC;CCLE	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	P04637	TP53	P24941	CDK2	T150	R156C	156	Missense	distal	6	no	10.420	10.423	EPSD	TCGA;ICGC;COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	P04637	TP53	P24941	CDK2	T150	P151T	151	Missense	proximal	1	no	10.420	0.463	EPSD	TCGA;ICGC;COSMIC	8.148	Loss
CMGC_CDK_CDK2_CDK2_ST	P04637	TP53	P24941	CDK2	T150	T155P	155	Missense	distal	5	no	10.420	10.446	EPSD	TCGA;ICGC;COSMIC;CCLE	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	P04637	TP53	P24941	CDK2	T150	V143G	143	Missense	distal	-7	no	10.420	10.725	EPSD	TCGA;ICGC;COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	P04637	TP53	P24941	CDK2	T150	P152Q	152	Missense	proximal	2	no	10.420	10.479	EPSD	TCGA;ICGC;COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	P04637	TP53	P24941	CDK2	T150	R156H	156	Missense	distal	6	no	10.420	10.432	EPSD	TCGA;ICGC;COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	P04637	TP53	P24941	CDK2	T150	L145P	145	Missense	distal	-5	no	10.420	10.409	EPSD	TCGA;ICGC;COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	P04637	TP53	P24941	CDK2	T150	Q144L	144	Missense	distal	-6	no	10.420	10.418	EPSD	TCGA;ICGC;COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	P04637	TP53	P24941	CDK2	T150	Q144H	144	Missense	distal	-6	no	10.420	10.421	EPSD	TCGA;ICGC;COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	P04637	TP53	P24941	CDK2	T150	G154V	154	Missense	distal	4	no	10.420	10.767	EPSD	TCGA;ICGC;COSMIC;GDSC;CCLE	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	P04637	TP53	P24941	CDK2	T150	V157L	157	Missense	distal	7	no	10.420	10.192	EPSD	TCGA;ICGC;COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	P04637	TP53	P24941	CDK2	T150	P151R	151	Missense	proximal	1	no	10.420	0.622	EPSD	TCGA;ICGC;COSMIC	8.148	Loss
CMGC_CDK_CDK2_CDK2_ST	P04637	TP53	P24941	CDK2	T150	Q144P	144	Missense	distal	-6	no	10.420	10.418	EPSD	TCGA;ICGC;COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	P04637	TP53	P24941	CDK2	T150	V143E	143	Missense	distal	-7	no	10.420	10.491	EPSD	TCGA;ICGC;COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	P04637	TP53	P24941	CDK2	T150	R156G	156	Missense	distal	6	no	10.420	10.425	EPSD	TCGA;ICGC;COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	P04637	TP53	P24941	CDK2	T150	P151L	151	Missense	proximal	1	no	10.420	0.599	EPSD	TCGA;ICGC;COSMIC	8.148	Loss
CMGC_CDK_CDK2_CDK2_ST	P04637	TP53	P24941	CDK2	T155	R156P	156	Missense	proximal	1	no	7.289	17.087	EPSD	TCGA;ICGC;COSMIC;GDSC;CCLE	8.148	Gain
CMGC_CDK_CDK2_CDK2_ST	P04637	TP53	P24941	CDK2	T155	R156H	156	Missense	proximal	1	no	7.289	10.329	EPSD	TCGA;ICGC;COSMIC	8.148	Gain
CMGC_CDK_CDK2_CDK2_ST	P04637	TP53	P24941	CDK2	T155	R156G	156	Missense	proximal	1	no	7.289	9.775	EPSD	TCGA;ICGC;COSMIC	8.148	Gain
CMGC_CDK_CDK2_CDK2_ST	P04637	TP53	P24941	CDK2	S315	K319N	319	Missense	distal	4	no	14.293	13.871	PhosphoSitePlus	TCGA;ICGC;COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	P04637	TP53	P24941	CDK2	S315	K320E	320	Missense	distal	5	no	14.293	14.426	PhosphoSitePlus	TCGA;ICGC;COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	P04637	TP53	P24941	CDK2	S315	S315C	315	Missense	central	0	yes	14.293	0.000	PhosphoSitePlus	TCGA;ICGC;COSMIC	8.148	Loss
CMGC_CDK_CDK2_CDK2_ST	Q9C0D5	TANC1	P24941	CDK2	S29	H36R	36	Missense	distal	7	no	12.404	12.762	EPSD	TCGA;ICGC;COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	Q9C0D5	TANC1	P24941	CDK2	S40	H36R	36	Missense	distal	-4	no	13.681	14.042	EPSD	TCGA;ICGC;COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	Q9C0D5	TANC1	P24941	CDK2	S67	S63F	63	Missense	distal	-4	no	13.809	12.847	EPSD	TCGA	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	Q9C0D5	TANC1	P24941	CDK2	S67	P68H	68	Missense	proximal	1	no	13.809	7.050	EPSD	TCGA;ICGC;COSMIC	8.148	Loss
CMGC_CDK_CDK2_CDK2_ST	Q9C0D5	TANC1	P24941	CDK2	S85	V89I	89	Missense	distal	4	no	13.901	13.646	EPSD	TCGA;ICGC;COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	Q9C0D5	TANC1	P24941	CDK2	S97	P101S	101	Missense	distal	4	no	14.444	14.457	EPSD	TCGA;ICGC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	Q9C0D5	TANC1	P24941	CDK2	S132	P133L	133	Missense	proximal	1	no	12.632	2.811	EPSD	TCGA;ICGC;COSMIC	8.148	Loss
CMGC_CDK_CDK2_CDK2_ST	Q9C0D5	TANC1	P24941	CDK2	S132	E137K	137	Missense	distal	5	no	12.632	12.499	EPSD	TCGA;ICGC;COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	Q9C0D5	TANC1	P24941	CDK2	S174	I173L	173	Missense	proximal	-1	no	12.827	12.665	EPSD	TCGA;ICGC;COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	Q9C0D5	TANC1	P24941	CDK2	S185	A184T	184	Missense	proximal	-1	no	13.043	13.050	EPSD	TCGA;ICGC;COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	Q9C0D5	TANC1	P24941	CDK2	S185	A184S	184	Missense	proximal	-1	no	13.043	12.842	EPSD	TCGA;ICGC;COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	Q9C0D5	TANC1	P24941	CDK2	S185	S182C	182	Missense	distal	-3	no	13.043	13.051	EPSD	TCGA;ICGC;COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	Q9C0D5	TANC1	P24941	CDK2	S185	P191L	191	Missense	distal	6	no	13.043	13.044	EPSD	TCGA;ICGC;COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	Q9C0D5	TANC1	P24941	CDK2	S207	E210K	210	Missense	distal	3	no	11.520	13.606	EPSD	TCGA;ICGC;COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	Q9C0D5	TANC1	P24941	CDK2	S207	P208L	208	Missense	proximal	1	no	11.520	1.700	EPSD	TCGA;ICGC;COSMIC	8.148	Loss
CMGC_CDK_CDK2_CDK2_ST	Q9C0D5	TANC1	P24941	CDK2	S207	P208S	208	Missense	proximal	1	no	11.520	0.255	EPSD	TCGA;ICGC;COSMIC	8.148	Loss
CMGC_CDK_CDK2_CDK2_ST	Q9C0D5	TANC1	P24941	CDK2	S207	A204T	204	Missense	distal	-3	no	11.520	11.539	EPSD	TCGA;ICGC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	Q9C0D5	TANC1	P24941	CDK2	S214	E210K	210	Missense	distal	-4	no	12.466	12.154	EPSD	TCGA;ICGC;COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	Q9C0D5	TANC1	P24941	CDK2	S214	P208S	208	Missense	distal	-6	no	12.466	12.465	EPSD	TCGA;ICGC;COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	Q9C0D5	TANC1	P24941	CDK2	S270	A273T	273	Missense	distal	3	no	13.080	13.478	EPSD	TCGA;ICGC;COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	Q9C0D5	TANC1	P24941	CDK2	S270	R264H	264	Missense	distal	-6	no	13.080	13.081	EPSD	TCGA;ICGC;COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	Q9C0D5	TANC1	P24941	CDK2	S444	R438G	438	Missense	distal	-6	no	14.217	14.218	EPSD	TCGA;ICGC;COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	Q9C0D5	TANC1	P24941	CDK2	S444	P445L	445	Missense	proximal	1	no	14.217	4.396	EPSD	TCGA;ICGC;COSMIC	8.148	Loss
CMGC_CDK_CDK2_CDK2_ST	Q9C0D5	TANC1	P24941	CDK2	S448	D453E	453	Missense	distal	5	no	11.399	11.304	EPSD	TCGA;ICGC;COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	Q9C0D5	TANC1	P24941	CDK2	S448	P445L	445	Missense	distal	-3	no	11.399	11.328	EPSD	TCGA;ICGC;COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	Q9C0D5	TANC1	P24941	CDK2	T461	P466Q	466	Missense	distal	5	no	14.436	14.396	EPSD	TCGA;ICGC;COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	Q9C0D5	TANC1	P24941	CDK2	T461	D457Y	457	Missense	distal	-4	no	14.436	14.375	EPSD	TCGA;ICGC;COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	Q9C0D5	TANC1	P24941	CDK2	T461	S467T	467	Missense	distal	6	no	14.436	14.443	EPSD	TCGA;ICGC;COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	Q9C0D5	TANC1	P24941	CDK2	T461	P462S	462	Missense	proximal	1	no	14.436	3.171	EPSD	TCGA;ICGC;COSMIC	8.148	Loss
CMGC_CDK_CDK2_CDK2_ST	Q9C0D5	TANC1	P24941	CDK2	T461	Q456H	456	Missense	distal	-5	no	14.436	14.483	EPSD	TCGA;ICGC;COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	Q9C0D5	TANC1	P24941	CDK2	T461	P462T	462	Missense	proximal	1	no	14.436	4.479	EPSD	TCGA;ICGC;COSMIC	8.148	Loss
CMGC_CDK_CDK2_CDK2_ST	Q9C0D5	TANC1	P24941	CDK2	T461	L464F	464	Missense	distal	3	no	14.436	14.779	EPSD	TCGA;ICGC;COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	Q9C0D5	TANC1	P24941	CDK2	T461	P466L	466	Missense	distal	5	no	14.436	14.476	EPSD	TCGA;ICGC;COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	Q9C0D5	TANC1	P24941	CDK2	S465	P466Q	466	Missense	proximal	1	no	14.984	7.073	EPSD	TCGA;ICGC;COSMIC	8.148	Loss
CMGC_CDK_CDK2_CDK2_ST	Q9C0D5	TANC1	P24941	CDK2	S465	S467T	467	Missense	proximal	2	no	14.984	14.740	EPSD	TCGA;ICGC;COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	Q9C0D5	TANC1	P24941	CDK2	S465	P462S	462	Missense	distal	-3	no	14.984	15.079	EPSD	TCGA;ICGC;COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	Q9C0D5	TANC1	P24941	CDK2	S465	S471I	471	Missense	distal	6	no	14.984	14.983	EPSD	TCGA;ICGC;COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	Q9C0D5	TANC1	P24941	CDK2	S465	P462T	462	Missense	distal	-3	no	14.984	14.945	EPSD	TCGA;ICGC;COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	Q9C0D5	TANC1	P24941	CDK2	S465	L464F	464	Missense	proximal	-1	no	14.984	15.949	EPSD	TCGA;ICGC;COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	Q9C0D5	TANC1	P24941	CDK2	S465	P466L	466	Missense	proximal	1	no	14.984	5.163	EPSD	TCGA;ICGC;COSMIC	8.148	Loss
CMGC_CDK_CDK2_CDK2_ST	Q9C0D5	TANC1	P24941	CDK2	T478	P479H	479	Missense	proximal	1	no	14.736	7.977	EPSD	TCGA;ICGC	8.148	Loss
CMGC_CDK_CDK2_CDK2_ST	Q9C0D5	TANC1	P24941	CDK2	T478	S471I	471	Missense	distal	-7	no	14.736	15.110	EPSD	TCGA;ICGC;COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	Q9C0D5	TANC1	P24941	CDK2	T478	A485V	485	Missense	distal	7	no	14.736	14.609	EPSD	TCGA;ICGC;COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	Q9C0D5	TANC1	P24941	CDK2	T910	R906S	906	Missense	distal	-4	no	14.257	14.854	EPSD	TCGA;ICGC;COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	Q9C0D5	TANC1	P24941	CDK2	T910	P911L	911	Missense	proximal	1	no	14.257	4.436	EPSD	TCGA;ICGC;COSMIC	8.148	Loss
CMGC_CDK_CDK2_CDK2_ST	Q9C0D5	TANC1	P24941	CDK2	T910	A903T	903	Missense	distal	-7	no	14.257	14.090	EPSD	TCGA;ICGC;COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	Q9C0D5	TANC1	P24941	CDK2	T1445	E1440K	1440	Missense	distal	-5	no	13.836	13.801	EPSD	TCGA;ICGC;COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	Q9C0D5	TANC1	P24941	CDK2	T1445	E1442K	1442	Missense	distal	-3	no	13.836	13.620	EPSD	TCGA;ICGC;COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	Q9C0D5	TANC1	P24941	CDK2	T1447	E1440K	1440	Missense	distal	-7	no	13.855	13.717	EPSD	TCGA;ICGC;COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	Q9C0D5	TANC1	P24941	CDK2	T1447	E1442K	1442	Missense	distal	-5	no	13.855	13.820	EPSD	TCGA;ICGC;COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	Q9C0D5	TANC1	P24941	CDK2	S1465	E1469Q	1469	Missense	distal	4	no	11.846	11.890	EPSD	TCGA;ICGC;COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	Q9C0D5	TANC1	P24941	CDK2	S1465	S1465Y	1465	Missense	central	0	yes	11.846	0.000	EPSD	TCGA;ICGC;COSMIC	8.148	Loss
CMGC_CDK_CDK2_CDK2_ST	Q9C0D5	TANC1	P24941	CDK2	S1465	S1470Y	1470	Missense	distal	5	no	11.846	12.020	EPSD	TCGA;ICGC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	Q9C0D5	TANC1	P24941	CDK2	S1503	P1501S	1501	Missense	proximal	-2	no	13.796	13.145	EPSD	TCGA;ICGC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	Q9C0D5	TANC1	P24941	CDK2	T1573	P1574S	1574	Missense	proximal	1	no	15.927	4.661	EPSD	TCGA;ICGC	8.148	Loss
CMGC_CDK_CDK2_CDK2_ST	Q9C0D5	TANC1	P24941	CDK2	T1573	P1574L	1574	Missense	proximal	1	no	15.927	6.106	EPSD	TCGA;ICGC	8.148	Loss
CMGC_CDK_CDK2_CDK2_ST	Q9C0D5	TANC1	P24941	CDK2	S1632	E1628D	1628	Missense	distal	-4	no	10.226	10.523	EPSD	TCGA;ICGC;COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	Q9C0D5	TANC1	P24941	CDK2	S1632	E1628K	1628	Missense	distal	-4	no	10.226	9.915	EPSD	TCGA;ICGC;COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	Q9C0D5	TANC1	P24941	CDK2	S1668	K1674Q	1674	Missense	distal	6	no	13.364	13.361	EPSD	TCGA;ICGC;COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	Q9C0D5	TANC1	P24941	CDK2	S1668	S1663L	1663	Missense	distal	-5	no	13.364	13.420	EPSD	TCGA;ICGC;COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	P51649	ALDH5A1	P24941	CDK2	T181	R187W	187	Missense	distal	6	no	19.210	19.202	PhosphoSitePlus	TCGA;ICGC;COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	Q5JTV8	TOR1AIP1	P24941	CDK2	T20	E27K	27	Missense	distal	7	no	12.521	12.190	EPSD	TCGA;ICGC;COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	Q5JTV8	TOR1AIP1	P24941	CDK2	T20	P21H	21	Missense	proximal	1	no	12.521	5.762	EPSD	TCGA;ICGC;COSMIC	8.148	Loss
CMGC_CDK_CDK2_CDK2_ST	Q5JTV8	TOR1AIP1	P24941	CDK2	T47	D41N	41	Missense	distal	-6	no	12.574	12.575	EPSD	TCGA;ICGC;COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	Q5JTV8	TOR1AIP1	P24941	CDK2	T47	R54Q	54	Missense	distal	7	no	12.574	11.930	EPSD	TCGA;ICGC;COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	Q5JTV8	TOR1AIP1	P24941	CDK2	S79	V74M	74	Missense	distal	-5	no	12.511	12.587	EPSD	TCGA;ICGC;COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	Q5JTV8	TOR1AIP1	P24941	CDK2	S228	Q225E	225	Missense	distal	-3	no	9.722	9.838	EPSD	TCGA;COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	Q5JTV8	TOR1AIP1	P24941	CDK2	S245	R240S	240	Missense	distal	-5	no	10.099	10.008	EPSD	TCGA;COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	Q5JTV8	TOR1AIP1	P24941	CDK2	S245	S252L	252	Missense	distal	7	no	10.099	10.281	EPSD	TCGA;COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	Q5JTV8	TOR1AIP1	P24941	CDK2	S245	E244Q	244	Missense	proximal	-1	no	10.099	9.006	EPSD	TCGA;COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	Q8TAP6	CEP76	P24941	CDK2	S83	S83C	83	Missense	central	0	yes	15.263	0.000	PhosphoSitePlus	TCGA;ICGC;COSMIC	8.148	Loss
CMGC_CDK_CDK2_CDK2_ST	Q8TAP6	CEP76	P24941	CDK2	T335	A340G	340	Missense	distal	5	no	17.340	17.456	EPSD	TCGA;ICGC;COSMIC	8.148	Up-regulation
Atypical_Alpha_eEF2K_EEF2K_ST	P13639	EEF2	O00418	EEF2K	T54	R50W	50	Missense	distal	-4	no	88.276	86.563	EPSD	TCGA;ICGC;COSMIC	53.998	Down-regulation
Atypical_Alpha_eEF2K_EEF2K_ST	P13639	EEF2	O00418	EEF2K	T54	R50P	50	Missense	distal	-4	no	88.276	87.769	EPSD	TCGA;ICGC;COSMIC	53.998	Down-regulation
Atypical_Alpha_eEF2K_EEF2K_ST	P13639	EEF2	O00418	EEF2K	T54	T57I	57	Missense	distal	3	no	88.276	81.158	EPSD	TCGA;ICGC;COSMIC	53.998	Down-regulation
Atypical_Alpha_eEF2K_EEF2K_ST	P13639	EEF2	O00418	EEF2K	T57	E63K	63	Missense	distal	6	no	90.548	93.590	PhosphoSitePlus	TCGA;ICGC;COSMIC	53.998	Up-regulation
Atypical_Alpha_eEF2K_EEF2K_ST	P13639	EEF2	O00418	EEF2K	T57	R50W	50	Missense	distal	-7	no	90.548	75.334	PhosphoSitePlus	TCGA;ICGC;COSMIC	53.998	Down-regulation
Atypical_Alpha_eEF2K_EEF2K_ST	P13639	EEF2	O00418	EEF2K	T57	T54S	54	Missense	distal	-3	no	90.548	89.412	PhosphoSitePlus	TCGA;ICGC;COSMIC	53.998	Down-regulation
Atypical_Alpha_eEF2K_EEF2K_ST	P13639	EEF2	O00418	EEF2K	T57	R50P	50	Missense	distal	-7	no	90.548	84.238	PhosphoSitePlus	TCGA;ICGC;COSMIC	53.998	Down-regulation
Atypical_Alpha_eEF2K_EEF2K_ST	P13639	EEF2	O00418	EEF2K	T57	T57I	57	Missense	central	0	yes	90.548	0.000	PhosphoSitePlus	TCGA;ICGC;COSMIC	53.998	Loss
Atypical_Alpha_eEF2K_EEF2K_ST	P13639	EEF2	O00418	EEF2K	T59	E63K	63	Missense	distal	4	no	87.039	87.541	EPSD	TCGA;ICGC;COSMIC	53.998	Up-regulation
Atypical_Alpha_eEF2K_EEF2K_ST	P13639	EEF2	O00418	EEF2K	T59	T54S	54	Missense	distal	-5	no	87.039	86.526	EPSD	TCGA;ICGC;COSMIC	53.998	Down-regulation
Atypical_Alpha_eEF2K_EEF2K_ST	P13639	EEF2	O00418	EEF2K	T59	T57I	57	Missense	proximal	-2	no	87.039	83.200	EPSD	TCGA;ICGC;COSMIC	53.998	Down-regulation
Atypical_Alpha_eEF2K_EEF2K_ST	P13639	EEF2	O00418	EEF2K	S802	G805D	805	Missense	distal	3	no	50.038	55.635	EPSD	TCGA;ICGC;COSMIC	53.998	Gain
Atypical_Alpha_eEF2K_EEF2K_ST	O00418	EEF2K	O00418	EEF2K	S71	E67K	67	Missense	distal	-4	no	59.038	60.268	EPSD	TCGA;ICGC;COSMIC	53.998	Up-regulation
Atypical_Alpha_eEF2K_EEF2K_ST	O00418	EEF2K	O00418	EEF2K	S71	R68W	68	Missense	distal	-3	no	59.038	60.856	EPSD	TCGA	53.998	Up-regulation
Atypical_Alpha_eEF2K_EEF2K_ST	O00418	EEF2K	O00418	EEF2K	S71	S74C	74	Missense	distal	3	no	59.038	43.841	EPSD	TCGA;ICGC;COSMIC	53.998	Loss
Atypical_Alpha_eEF2K_EEF2K_ST	O00418	EEF2K	O00418	EEF2K	T348	A346S	346	Missense	proximal	-2	no	105.565	106.225	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	53.998	Up-regulation
Atypical_Alpha_eEF2K_EEF2K_ST	O00418	EEF2K	O00418	EEF2K	T348	R351K	351	Missense	distal	3	no	105.565	101.421	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	53.998	Down-regulation
Atypical_Alpha_eEF2K_EEF2K_ST	O00418	EEF2K	O00418	EEF2K	T353	A346S	346	Missense	distal	-7	no	92.253	94.866	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	53.998	Up-regulation
Atypical_Alpha_eEF2K_EEF2K_ST	O00418	EEF2K	O00418	EEF2K	T353	R351K	351	Missense	proximal	-2	no	92.253	92.380	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	53.998	Up-regulation
Atypical_Alpha_eEF2K_EEF2K_ST	O00418	EEF2K	O00418	EEF2K	S366	S366F	366	Missense	central	0	yes	100.807	0.000	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	53.998	Loss
Atypical_Alpha_eEF2K_EEF2K_ST	O00418	EEF2K	O00418	EEF2K	S366	S366C	366	Missense	central	0	yes	100.807	0.000	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	53.998	Loss
Atypical_Alpha_eEF2K_EEF2K_ST	O00418	EEF2K	O00418	EEF2K	S366	P371S	371	Missense	distal	5	no	100.807	93.740	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	53.998	Down-regulation
Atypical_Alpha_eEF2K_EEF2K_ST	O00418	EEF2K	O00418	EEF2K	S396	A400V	400	Missense	distal	4	no	101.933	105.298	PhosphoSitePlus;EPSD	TCGA;ICGC;COSMIC	53.998	Up-regulation
Atypical_Alpha_eEF2K_EEF2K_ST	O00418	EEF2K	O00418	EEF2K	S396	S396F	396	Missense	central	0	yes	101.933	0.000	PhosphoSitePlus;EPSD	TCGA;ICGC;COSMIC	53.998	Loss
Atypical_Alpha_eEF2K_EEF2K_ST	O00418	EEF2K	O00418	EEF2K	S396	S392F	392	Missense	distal	-4	no	101.933	100.154	PhosphoSitePlus;EPSD	TCGA;ICGC;COSMIC	53.998	Down-regulation
Atypical_Alpha_eEF2K_EEF2K_ST	O00418	EEF2K	O00418	EEF2K	S396	D391N	391	Missense	distal	-5	no	101.933	100.941	PhosphoSitePlus;EPSD	TCGA;ICGC	53.998	Down-regulation
Atypical_Alpha_eEF2K_EEF2K_ST	O00418	EEF2K	O00418	EEF2K	S474	E472G	472	Missense	proximal	-2	no	112.113	112.469	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	53.998	Up-regulation
Atypical_Alpha_eEF2K_EEF2K_ST	O00418	EEF2K	O00418	EEF2K	S474	E472K	472	Missense	proximal	-2	no	112.113	113.140	EPSD;PhosphoSitePlus	TCGA;ICGC	53.998	Up-regulation
AGC_PKG_PRKG1_ST	P50552	VASP	Q13976	PRKG1	S157	R154C	154	Missense	distal	-3	no	13.230	6.208	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	7.092	Loss
AGC_PKG_PRKG1_ST	P50552	VASP	Q13976	PRKG1	S239	E242D	242	Missense	distal	3	no	11.551	11.565	PhosphoSitePlus;EPSD	TCGA;ICGC;COSMIC	7.092	Up-regulation
AGC_PKG_PRKG1_ST	P50552	VASP	Q13976	PRKG1	S305	R298T	298	Missense	distal	-7	no	8.159	7.314	EPSD	TCGA;ICGC;COSMIC	7.092	Down-regulation
AGC_PKG_PRKG1_ST	P50552	VASP	Q13976	PRKG1	S305	W310C	310	Missense	distal	5	no	8.159	8.190	EPSD	TCGA;ICGC	7.092	Up-regulation
AGC_PKG_PRKG1_ST	P50552	VASP	Q13976	PRKG1	S305	Q302H	302	Missense	distal	-3	no	8.159	5.927	EPSD	TCGA;ICGC;COSMIC	7.092	Loss
AGC_PKG_PRKG1_ST	P50552	VASP	Q13976	PRKG1	S305	R307Q	307	Missense	proximal	2	no	8.159	8.153	EPSD	TCGA;ICGC;COSMIC	7.092	Down-regulation
AGC_PKG_PRKG1_ST	P50552	VASP	Q13976	PRKG1	S305	R307W	307	Missense	proximal	2	no	8.159	8.059	EPSD	TCGA;ICGC	7.092	Down-regulation
AGC_PKG_PRKG1_ST	P50552	VASP	Q13976	PRKG1	S305	K312T	312	Missense	distal	7	no	8.159	8.152	EPSD	TCGA;ICGC;COSMIC	7.092	Down-regulation
AGC_PKG_PRKG1_ST	P50552	VASP	Q13976	PRKG1	S314	W310C	310	Missense	distal	-4	no	7.455	7.667	EPSD	TCGA;ICGC	7.092	Up-regulation
AGC_PKG_PRKG1_ST	P50552	VASP	Q13976	PRKG1	S314	R319W	319	Missense	distal	5	no	7.455	7.355	EPSD	TCGA;ICGC;COSMIC	7.092	Down-regulation
AGC_PKG_PRKG1_ST	P50552	VASP	Q13976	PRKG1	S314	R307Q	307	Missense	distal	-7	no	7.455	6.779	EPSD	TCGA;ICGC;COSMIC	7.092	Loss
AGC_PKG_PRKG1_ST	P50552	VASP	Q13976	PRKG1	S314	P318S	318	Missense	distal	4	no	7.455	7.304	EPSD	TCGA;ICGC;COSMIC	7.092	Down-regulation
AGC_PKG_PRKG1_ST	P50552	VASP	Q13976	PRKG1	S314	R307W	307	Missense	distal	-7	no	7.455	5.690	EPSD	TCGA;ICGC	7.092	Loss
AGC_PKG_PRKG1_ST	P50552	VASP	Q13976	PRKG1	S314	K312T	312	Missense	proximal	-2	no	7.455	5.340	EPSD	TCGA;ICGC;COSMIC	7.092	Loss
AGC_PKG_PRKG1_ST	P50552	VASP	Q13976	PRKG1	S322	R319W	319	Missense	distal	-3	no	11.110	3.437	EPSD	TCGA;ICGC;COSMIC	7.092	Loss
AGC_PKG_PRKG1_ST	P50552	VASP	Q13976	PRKG1	S322	P318S	318	Missense	distal	-4	no	11.110	11.533	EPSD	TCGA;ICGC;COSMIC	7.092	Up-regulation
AGC_PKG_PRKG1_ST	P50552	VASP	Q13976	PRKG1	S323	E330K	330	Missense	distal	7	no	8.265	8.349	EPSD	TCGA;ICGC;COSMIC	7.092	Up-regulation
AGC_PKG_PRKG1_ST	P50552	VASP	Q13976	PRKG1	S323	R319W	319	Missense	distal	-4	no	8.265	7.092	EPSD	TCGA;ICGC;COSMIC	7.092	Down-regulation
AGC_PKG_PRKG1_ST	P50552	VASP	Q13976	PRKG1	S323	P318S	318	Missense	distal	-5	no	8.265	8.150	EPSD	TCGA;ICGC;COSMIC	7.092	Down-regulation
AGC_PKG_PRKG1_ST	P50552	VASP	Q13976	PRKG1	S324	R319W	319	Missense	distal	-5	no	6.959	7.283	EPSD	TCGA;ICGC;COSMIC	7.092	Gain
AGC_PKG_PRKG1_ST	P50552	VASP	Q13976	PRKG1	S324	P318S	318	Missense	distal	-6	no	6.959	7.274	EPSD	TCGA;ICGC;COSMIC	7.092	Gain
AGC_PKG_PRKG1_ST	P61224	RAP1B	Q13976	PRKG1	S179	R176L	176	Missense	distal	-3	no	11.839	4.695	PhosphoSitePlus	TCGA;ICGC;COSMIC	7.092	Loss
AGC_PKG_PRKG1_ST	P61224	RAP1B	Q13976	PRKG1	S179	R176H	176	Missense	distal	-3	no	11.839	5.771	PhosphoSitePlus	TCGA;ICGC;COSMIC	7.092	Loss
AGC_PKG_PRKG1_ST	P61224	RAP1B	Q13976	PRKG1	S180	R176L	176	Missense	distal	-4	no	10.845	9.602	EPSD	TCGA;ICGC;COSMIC	7.092	Down-regulation
AGC_PKG_PRKG1_ST	P61224	RAP1B	Q13976	PRKG1	S180	R176H	176	Missense	distal	-4	no	10.845	10.089	EPSD	TCGA;ICGC;COSMIC	7.092	Down-regulation
AGC_PKG_PRKG1_ST	P43694	GATA4	Q13976	PRKG1	S262	R265H	265	Missense	distal	3	no	14.320	14.476	PhosphoSitePlus	TCGA;COSMIC	7.092	Up-regulation
AGC_PKG_PRKG1_ST	P43694	GATA4	Q13976	PRKG1	S262	R260W	260	Missense	proximal	-2	no	14.320	8.990	PhosphoSitePlus	TCGA	7.092	Down-regulation
AGC_PKG_PRKG1_ST	P43694	GATA4	Q13976	PRKG1	S262	A263T	263	Missense	proximal	1	no	14.320	14.283	PhosphoSitePlus	TCGA;COSMIC	7.092	Down-regulation
AGC_PKG_PRKG1_ST	P43694	GATA4	Q13976	PRKG1	S262	P257L	257	Missense	distal	-5	no	14.320	14.441	PhosphoSitePlus	TCGA;COSMIC	7.092	Up-regulation
AGC_PKG_PRKG1_ST	P61586	RHOA	Q13976	PRKG1	S73	D76Y	76	Missense	distal	3	no	7.618	7.605	EPSD	TCGA;ICGC;COSMIC	7.092	Down-regulation
AGC_PKG_PRKG1_ST	P61586	RHOA	Q13976	PRKG1	S73	L69P	69	Missense	distal	-4	no	7.618	7.968	EPSD	TCGA;ICGC;COSMIC;GDSC;CCLE	7.092	Up-regulation
AGC_PKG_PRKG1_ST	P61586	RHOA	Q13976	PRKG1	S73	R68C	68	Missense	distal	-5	no	7.618	7.875	EPSD	TCGA;ICGC;COSMIC	7.092	Up-regulation
AGC_PKG_PRKG1_ST	P61586	RHOA	Q13976	PRKG1	S73	R70S	70	Missense	distal	-3	no	7.618	2.130	EPSD	TCGA;ICGC;COSMIC	7.092	Loss
AGC_PKG_PRKG1_ST	P61586	RHOA	Q13976	PRKG1	S73	Y66N	66	Missense	distal	-7	no	7.618	7.800	EPSD	TCGA;ICGC;COSMIC	7.092	Up-regulation
AGC_PKG_PRKG1_ST	P61586	RHOA	Q13976	PRKG1	S73	S73F	73	Missense	central	0	yes	7.618	0.000	EPSD	TCGA;ICGC;COSMIC;CCLE	7.092	Loss
AGC_PKG_PRKG1_ST	P61586	RHOA	Q13976	PRKG1	S73	S73P	73	Missense	central	0	yes	7.618	0.000	EPSD	TCGA;ICGC;COSMIC	7.092	Loss
AGC_PKG_PRKG1_ST	P61586	RHOA	Q13976	PRKG1	S73	P75S	75	Missense	proximal	2	no	7.618	7.716	EPSD	TCGA;ICGC;COSMIC	7.092	Up-regulation
AGC_PKG_PRKG1_ST	P61586	RHOA	Q13976	PRKG1	S73	L69M	69	Missense	distal	-4	no	7.618	8.258	EPSD	TCGA;ICGC;COSMIC;CCLE	7.092	Up-regulation
AGC_PKG_PRKG1_ST	P61586	RHOA	Q13976	PRKG1	S188	R183C	183	Missense	distal	-5	no	11.288	11.545	PhosphoSitePlus	TCGA;ICGC;COSMIC	7.092	Up-regulation
AGC_PKG_PRKG1_ST	P10644	PRKAR1A	Q13976	PRKG1	T73	S77L	77	Missense	distal	4	no	7.426	7.677	EPSD	TCGA;ICGC;COSMIC	7.092	Up-regulation
AGC_PKG_PRKG1_ST	P10644	PRKAR1A	Q13976	PRKG1	T73	Q69H	69	Missense	distal	-4	no	7.426	7.065	EPSD	TCGA;ICGC;COSMIC	7.092	Loss
AGC_PKG_PRKG1_ST	P10644	PRKAR1A	Q13976	PRKG1	S77	S77L	77	Missense	central	0	yes	11.169	0.000	EPSD	TCGA;ICGC;COSMIC	7.092	Loss
AGC_PKG_PRKG1_ST	P10644	PRKAR1A	Q13976	PRKG1	S77	E81D	81	Missense	distal	4	no	11.169	11.182	EPSD	TCGA;ICGC	7.092	Up-regulation
AGC_PKG_PRKG1_ST	P10644	PRKAR1A	Q13976	PRKG1	S101	T106M	106	Missense	distal	5	no	8.702	8.701	PhosphoSitePlus	TCGA;ICGC;COSMIC	7.092	Down-regulation
AGC_PKG_PRKG1_ST	P10644	PRKAR1A	Q13976	PRKG1	S307	L303V	303	Missense	distal	-4	no	9.166	9.409	EPSD	TCGA;ICGC;COSMIC	7.092	Up-regulation
AGC_PKG_PRKG1_ST	P10644	PRKAR1A	Q13976	PRKG1	S307	R306Q	306	Missense	proximal	-1	no	9.166	9.102	EPSD	TCGA;ICGC;COSMIC;GDSC;CCLE	7.092	Down-regulation
AGC_PKG_PRKG1_ST	P11831	SRF	Q13976	PRKG1	S237	E242K	242	Missense	distal	5	no	10.171	10.234	EPSD	TCGA;COSMIC	7.092	Up-regulation
AGC_PKG_PRKG1_ST	P11831	SRF	Q13976	PRKG1	S237	T244R	244	Missense	distal	7	no	10.171	10.221	EPSD	TCGA;COSMIC	7.092	Up-regulation
AGC_PKG_PRKG1_ST	P21731	TBXA2R	Q13976	PRKG1	S324	R318H	318	Missense	distal	-6	no	11.181	10.656	EPSD	TCGA	7.092	Down-regulation
AGC_PKG_PRKG1_ST	P21731	TBXA2R	Q13976	PRKG1	S324	R326Q	326	Missense	proximal	2	no	11.181	11.174	EPSD	TCGA;ICGC;COSMIC	7.092	Down-regulation
AGC_PKG_PRKG1_ST	P21731	TBXA2R	Q13976	PRKG1	S329	R326Q	326	Missense	distal	-3	no	11.239	7.404	EPSD	TCGA;ICGC;COSMIC	7.092	Down-regulation
AGC_PKG_PRKG1_ST	P21731	TBXA2R	Q13976	PRKG1	S331	R326Q	326	Missense	distal	-5	no	9.685	9.806	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	7.092	Up-regulation
AGC_PKG_PRKG1_ST	P35520	CBS	Q13976	PRKG1	S61	S61C	61	Missense	central	0	yes	10.262	0.000	EPSD	TCGA;ICGC;COSMIC	7.092	Loss
AGC_PKG_PRKG1_ST	P35520	CBS	Q13976	PRKG1	S61	P59S	59	Missense	proximal	-2	no	10.262	10.613	EPSD	TCGA;ICGC	7.092	Up-regulation
AGC_PKG_PRKG1_ST	P35520	CBS	Q13976	PRKG1	T193	R196S	196	Missense	distal	3	no	9.520	9.585	EPSD	TCGA;COSMIC	7.092	Up-regulation
AGC_PKG_PRKG1_ST	P35520	CBS	Q13976	PRKG1	T193	P200L	200	Missense	distal	7	no	9.520	9.455	EPSD	TCGA;COSMIC	7.092	Down-regulation
AGC_PKG_PRKG1_ST	P35520	CBS	Q13976	PRKG1	T193	S199F	199	Missense	distal	6	no	9.520	9.712	EPSD	TCGA;COSMIC;GDSC;CCLE	7.092	Up-regulation
AGC_PKG_PRKG1_ST	P35520	CBS	Q13976	PRKG1	T193	A186T	186	Missense	distal	-7	no	9.520	9.466	EPSD	TCGA	7.092	Down-regulation
AGC_PKG_PRKG1_ST	P35520	CBS	Q13976	PRKG1	T193	E187D	187	Missense	distal	-6	no	9.520	9.376	EPSD	TCGA;COSMIC	7.092	Down-regulation
AGC_PKG_PRKG1_ST	P35520	CBS	Q13976	PRKG1	S199	R196S	196	Missense	distal	-3	no	8.007	2.518	EPSD	TCGA;COSMIC	7.092	Loss
AGC_PKG_PRKG1_ST	P35520	CBS	Q13976	PRKG1	S199	P200L	200	Missense	proximal	1	no	8.007	7.776	EPSD	TCGA;COSMIC	7.092	Down-regulation
AGC_PKG_PRKG1_ST	P35520	CBS	Q13976	PRKG1	S199	S199F	199	Missense	central	0	yes	8.007	0.000	EPSD	TCGA;COSMIC;GDSC;CCLE	7.092	Loss
AGC_PKG_PRKG1_ST	P35520	CBS	Q13976	PRKG1	S227	D234N	234	Missense	distal	7	no	8.362	8.405	PhosphoSitePlus;EPSD	TCGA;COSMIC	7.092	Up-regulation
AGC_PKG_PRKG1_ST	P35520	CBS	Q13976	PRKG1	S227	R224C	224	Missense	distal	-3	no	8.362	1.340	PhosphoSitePlus;EPSD	TCGA;COSMIC	7.092	Loss
AGC_PKG_PRKG1_ST	P35520	CBS	Q13976	PRKG1	S227	H232Q	232	Missense	distal	5	no	8.362	8.387	PhosphoSitePlus;EPSD	TCGA	7.092	Up-regulation
AGC_PKG_PRKG1_ST	P35520	CBS	Q13976	PRKG1	S227	A231T	231	Missense	distal	4	no	8.362	8.365	PhosphoSitePlus;EPSD	TCGA;COSMIC	7.092	Up-regulation
AGC_PKG_PRKG1_ST	P35520	CBS	Q13976	PRKG1	S525	R527Q	527	Missense	proximal	2	no	8.571	8.564	EPSD;PhosphoSitePlus	TCGA;COSMIC;CCLE	7.092	Down-regulation
AGC_PKG_PRKG1_ST	Q9Y210	TRPC6	Q13976	PRKG1	S28	D35H	35	Missense	distal	7	no	8.754	8.812	EPSD	TCGA;ICGC;COSMIC	7.092	Up-regulation
AGC_PKG_PRKG1_ST	Q9Y210	TRPC6	Q13976	PRKG1	S28	M34I	34	Missense	distal	6	no	8.754	9.033	EPSD	TCGA;ICGC;COSMIC	7.092	Up-regulation
AGC_PKG_PRKG1_ST	Q9Y210	TRPC6	Q13976	PRKG1	S28	R25C	25	Missense	distal	-3	no	8.754	1.732	EPSD	TCGA	7.092	Loss
AGC_PKG_PRKG1_ST	Q9Y210	TRPC6	Q13976	PRKG1	S28	R25H	25	Missense	distal	-3	no	8.754	2.687	EPSD	TCGA;ICGC;COSMIC;CCLE	7.092	Loss
AGC_PKG_PRKG1_ST	Q9Y210	TRPC6	Q13976	PRKG1	T70	R68W	68	Missense	proximal	-2	no	12.250	6.920	PhosphoSitePlus;EPSD	TCGA;ICGC;COSMIC	7.092	Loss
AGC_PKG_PRKG1_ST	Q9Y210	TRPC6	Q13976	PRKG1	T70	R73H	73	Missense	distal	3	no	12.250	12.406	PhosphoSitePlus;EPSD	TCGA;ICGC;COSMIC	7.092	Up-regulation
AGC_PKG_PRKG1_ST	Q9Y210	TRPC6	Q13976	PRKG1	T70	R68Q	68	Missense	proximal	-2	no	12.250	9.285	PhosphoSitePlus;EPSD	TCGA;ICGC;COSMIC	7.092	Down-regulation
AGC_PKG_PRKG1_ST	Q9Y210	TRPC6	Q13976	PRKG1	T70	R73C	73	Missense	distal	3	no	12.250	12.473	PhosphoSitePlus;EPSD	TCGA;ICGC;COSMIC	7.092	Up-regulation
AGC_PKG_PRKG1_ST	Q9Y210	TRPC6	Q13976	PRKG1	T70	R63K	63	Missense	distal	-7	no	12.250	11.784	PhosphoSitePlus;EPSD	TCGA;ICGC;COSMIC	7.092	Down-regulation
AGC_PKG_PRKG1_ST	Q9Y210	TRPC6	Q13976	PRKG1	T70	R67W	67	Missense	distal	-3	no	12.250	4.578	PhosphoSitePlus;EPSD	TCGA;ICGC;COSMIC	7.092	Loss
AGC_PKG_PRKG1_ST	Q9Y210	TRPC6	Q13976	PRKG1	T70	L72R	72	Missense	proximal	2	no	12.250	12.381	PhosphoSitePlus;EPSD	TCGA;ICGC;COSMIC	7.092	Up-regulation
AGC_PKG_PRKG1_ST	Q9Y210	TRPC6	Q13976	PRKG1	S94	R91P	91	Missense	distal	-3	no	9.035	4.134	EPSD	TCGA;ICGC;COSMIC	7.092	Loss
AGC_PKG_PRKG1_ST	Q9Y210	TRPC6	Q13976	PRKG1	S94	R91C	91	Missense	distal	-3	no	9.035	2.013	EPSD	TCGA;ICGC;COSMIC	7.092	Loss
AGC_PKG_PRKG1_ST	Q9Y210	TRPC6	Q13976	PRKG1	S94	R101H	101	Missense	distal	7	no	9.035	8.952	EPSD	TCGA;ICGC;COSMIC	7.092	Down-regulation
AGC_PKG_PRKG1_ST	Q9Y210	TRPC6	Q13976	PRKG1	S94	S89I	89	Missense	distal	-5	no	9.035	9.262	EPSD	TCGA;ICGC;COSMIC	7.092	Up-regulation
AGC_PKG_PRKG1_ST	Q9Y210	TRPC6	Q13976	PRKG1	S94	E99K	99	Missense	distal	5	no	9.035	9.098	EPSD	TCGA;ICGC;COSMIC	7.092	Up-regulation
AGC_PKG_PRKG1_ST	Q9Y210	TRPC6	Q13976	PRKG1	S94	E98D	98	Missense	distal	4	no	9.035	9.049	EPSD	TCGA;ICGC;COSMIC	7.092	Up-regulation
AGC_PKG_PRKG1_ST	Q9Y210	TRPC6	Q13976	PRKG1	S322	V329G	329	Missense	distal	7	no	9.394	9.413	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	7.092	Up-regulation
AGC_PKG_PRKG1_ST	Q9Y210	TRPC6	Q13976	PRKG1	S322	K319Q	319	Missense	distal	-3	no	9.394	7.917	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	7.092	Down-regulation
AGC_PKG_PRKG1_ST	Q9Y210	TRPC6	Q13976	PRKG1	S785	W783C	783	Missense	proximal	-2	no	6.984	7.585	EPSD	TCGA;ICGC;COSMIC	7.092	Gain
AGC_PKG_PRKG1_ST	Q9Y210	TRPC6	Q13976	PRKG1	S785	I784S	784	Missense	proximal	-1	no	6.984	7.185	EPSD	TCGA;ICGC;COSMIC	7.092	Gain
AGC_PKG_PRKG1_ST	Q9Y210	TRPC6	Q13976	PRKG1	S836	D842Y	842	Missense	distal	6	no	8.089	8.050	EPSD	TCGA;ICGC;COSMIC	7.092	Down-regulation
AGC_PKG_PRKG1_ST	Q9Y210	TRPC6	Q13976	PRKG1	S836	P835T	835	Missense	proximal	-1	no	8.089	8.191	EPSD	TCGA;ICGC;COSMIC	7.092	Up-regulation
AGC_PKG_PRKG1_ST	Q9Y210	TRPC6	Q13976	PRKG1	S836	V829A	829	Missense	distal	-7	no	8.089	8.792	EPSD	TCGA;ICGC;COSMIC	7.092	Up-regulation
AGC_PKG_PRKG1_ST	Q9Y210	TRPC6	Q13976	PRKG1	S836	S836I	836	Missense	central	0	yes	8.089	0.000	EPSD	TCGA;ICGC	7.092	Loss
AGC_PKG_PRKG1_ST	Q9Y210	TRPC6	Q13976	PRKG1	S836	P835S	835	Missense	proximal	-1	no	8.089	8.192	EPSD	TCGA;ICGC;COSMIC	7.092	Up-regulation
AGC_PKG_PRKG1_ST	P35367	HRH1	Q13976	PRKG1	T142	Y138S	138	Missense	distal	-4	no	7.063	7.503	EPSD	TCGA;ICGC;COSMIC	7.092	Gain
AGC_PKG_PRKG1_ST	P35367	HRH1	Q13976	PRKG1	S255	P256S	256	Missense	proximal	1	no	7.729	7.991	EPSD	TCGA;ICGC;COSMIC	7.092	Up-regulation
AGC_PKG_PRKG1_ST	P35367	HRH1	Q13976	PRKG1	S255	G252V	252	Missense	distal	-3	no	7.729	6.639	EPSD	TCGA;ICGC;COSMIC	7.092	Loss
AGC_PKG_PRKG1_ST	P35367	HRH1	Q13976	PRKG1	S277	T279S	279	Missense	proximal	2	no	8.189	8.220	EPSD	TCGA;ICGC;COSMIC	7.092	Up-regulation
AGC_PKG_PRKG1_ST	P35367	HRH1	Q13976	PRKG1	S277	P276S	276	Missense	proximal	-1	no	8.189	8.292	EPSD	TCGA;ICGC;COSMIC	7.092	Up-regulation
AGC_PKG_PRKG1_ST	P35367	HRH1	Q13976	PRKG1	S277	P280S	280	Missense	distal	3	no	8.189	7.939	EPSD	TCGA;ICGC;COSMIC	7.092	Down-regulation
AGC_PKG_PRKG1_ST	P35367	HRH1	Q13976	PRKG1	S277	P280L	280	Missense	distal	3	no	8.189	8.307	EPSD	TCGA;ICGC;COSMIC	7.092	Up-regulation
AGC_PKG_PRKG1_ST	P35367	HRH1	Q13976	PRKG1	S363	S363L	363	Missense	central	0	yes	10.249	0.000	EPSD	TCGA;ICGC;COSMIC	7.092	Loss
AGC_PKG_PRKG1_ST	P35367	HRH1	Q13976	PRKG1	S363	S357F	357	Missense	distal	-6	no	10.249	9.953	EPSD	TCGA;ICGC;COSMIC	7.092	Down-regulation
AGC_PKG_PRKG1_ST	P35367	HRH1	Q13976	PRKG1	S380	R377S	377	Missense	distal	-3	no	9.236	3.748	EPSD	TCGA;ICGC;COSMIC	7.092	Loss
AGC_PKG_PRKG1_ST	P35367	HRH1	Q13976	PRKG1	S380	R377K	377	Missense	distal	-3	no	9.236	6.878	EPSD	TCGA;ICGC;COSMIC	7.092	Loss
AGC_PKG_PRKG1_ST	P35367	HRH1	Q13976	PRKG1	S396	S396L	396	Missense	central	0	yes	8.063	0.000	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	7.092	Loss
AGC_PKG_PRKG1_ST	P35367	HRH1	Q13976	PRKG1	S396	R395H	395	Missense	proximal	-1	no	8.063	7.915	EPSD;PhosphoSitePlus	TCGA;ICGC	7.092	Down-regulation
AGC_PKG_PRKG1_ST	P35367	HRH1	Q13976	PRKG1	S398	S396L	396	Missense	proximal	-2	no	9.845	7.959	PhosphoSitePlus;EPSD	TCGA;ICGC;COSMIC	7.092	Down-regulation
AGC_PKG_PRKG1_ST	P35367	HRH1	Q13976	PRKG1	S398	R395H	395	Missense	distal	-3	no	9.845	3.777	PhosphoSitePlus;EPSD	TCGA;ICGC	7.092	Loss
AGC_PKG_PRKG1_ST	Q9NS28	RGS18	Q13976	PRKG1	S49	E43K	43	Missense	distal	-6	no	6.890	7.371	EPSD	TCGA;ICGC;COSMIC	7.092	Gain
AGC_PKG_PRKG1_ST	Q9NS28	RGS18	Q13976	PRKG1	S64	R62H	62	Missense	proximal	-2	no	8.410	4.152	EPSD	TCGA;ICGC;COSMIC	7.092	Loss
AGC_PKG_PRKG1_ST	Q9NS28	RGS18	Q13976	PRKG1	S64	L69V	69	Missense	distal	5	no	8.410	8.461	EPSD	TCGA;ICGC;COSMIC	7.092	Up-regulation
AGC_PKG_PRKG1_ST	Q9NS28	RGS18	Q13976	PRKG1	S64	R62C	62	Missense	proximal	-2	no	8.410	3.681	EPSD	TCGA;ICGC;COSMIC	7.092	Loss
AGC_PKG_PRKG1_ST	Q9NS28	RGS18	Q13976	PRKG1	S64	T61A	61	Missense	distal	-3	no	8.410	8.997	EPSD	TCGA;ICGC;COSMIC	7.092	Up-regulation
AGC_PKG_PRKG1_ST	Q9NS28	RGS18	Q13976	PRKG1	S64	H68Q	68	Missense	distal	4	no	8.410	8.351	EPSD	TCGA;ICGC	7.092	Down-regulation
AGC_PKG_PRKG1_ST	Q9NS28	RGS18	Q13976	PRKG1	S76	L69V	69	Missense	distal	-7	no	6.984	7.505	EPSD	TCGA;ICGC;COSMIC	7.092	Gain
AGC_PKG_PRKG1_ST	Q9NS28	RGS18	Q13976	PRKG1	S216	R217S	217	Missense	proximal	1	no	13.647	13.472	PhosphoSitePlus	TCGA	7.092	Down-regulation
AGC_PKG_PRKG1_ST	Q9NS28	RGS18	Q13976	PRKG1	S216	R215P	215	Missense	proximal	-1	no	13.647	13.442	PhosphoSitePlus	TCGA;ICGC;COSMIC	7.092	Down-regulation
AGC_PKG_PRKG1_ST	Q9NS28	RGS18	Q13976	PRKG1	S216	R217L	217	Missense	proximal	1	no	13.647	12.980	PhosphoSitePlus	TCGA;ICGC;COSMIC;GDSC;CCLE	7.092	Down-regulation
AGC_PKG_PRKG1_ST	Q9NS28	RGS18	Q13976	PRKG1	S216	R215Q	215	Missense	proximal	-1	no	13.647	13.582	PhosphoSitePlus	TCGA;ICGC;COSMIC	7.092	Down-regulation
AGC_PKG_PRKG1_ST	Q9NS28	RGS18	Q13976	PRKG1	S216	R213M	213	Missense	distal	-3	no	13.647	8.343	PhosphoSitePlus	TCGA;ICGC;COSMIC	7.092	Down-regulation
AGC_PKG_PRKG1_ST	Q9NS28	RGS18	Q13976	PRKG1	S218	R217S	217	Missense	proximal	-1	no	12.201	12.100	EPSD	TCGA	7.092	Down-regulation
AGC_PKG_PRKG1_ST	Q9NS28	RGS18	Q13976	PRKG1	S218	R215P	215	Missense	distal	-3	no	12.201	7.300	EPSD	TCGA;ICGC;COSMIC	7.092	Down-regulation
AGC_PKG_PRKG1_ST	Q9NS28	RGS18	Q13976	PRKG1	S218	R217L	217	Missense	proximal	-1	no	12.201	11.899	EPSD	TCGA;ICGC;COSMIC;GDSC;CCLE	7.092	Down-regulation
AGC_PKG_PRKG1_ST	Q9NS28	RGS18	Q13976	PRKG1	S218	R215Q	215	Missense	distal	-3	no	12.201	8.367	EPSD	TCGA;ICGC;COSMIC	7.092	Down-regulation
AGC_PKG_PRKG1_ST	Q9NS28	RGS18	Q13976	PRKG1	S218	R213M	213	Missense	distal	-5	no	12.201	12.363	EPSD	TCGA;ICGC;COSMIC	7.092	Up-regulation
AGC_PKG_PRKG1_ST	Q9NS28	RGS18	Q13976	PRKG1	T220	R217S	217	Missense	distal	-3	no	8.743	3.254	EPSD	TCGA	7.092	Loss
AGC_PKG_PRKG1_ST	Q9NS28	RGS18	Q13976	PRKG1	T220	R215P	215	Missense	distal	-5	no	8.743	8.998	EPSD	TCGA;ICGC;COSMIC	7.092	Up-regulation
AGC_PKG_PRKG1_ST	Q9NS28	RGS18	Q13976	PRKG1	T220	R217L	217	Missense	distal	-3	no	8.743	1.599	EPSD	TCGA;ICGC;COSMIC;GDSC;CCLE	7.092	Loss
AGC_PKG_PRKG1_ST	Q9NS28	RGS18	Q13976	PRKG1	T220	R215Q	215	Missense	distal	-5	no	8.743	8.864	EPSD	TCGA;ICGC;COSMIC	7.092	Up-regulation
AGC_PKG_PRKG1_ST	Q9NS28	RGS18	Q13976	PRKG1	T220	R213M	213	Missense	distal	-7	no	8.743	7.855	EPSD	TCGA;ICGC;COSMIC	7.092	Down-regulation
AGC_PKG_PRKG1_ST	Q9NS28	RGS18	Q13976	PRKG1	T220	D226N	226	Missense	distal	6	no	8.743	8.653	EPSD	TCGA;ICGC	7.092	Down-regulation
AGC_PKG_PRKG1_ST	Q9Y613	FHOD1	Q13976	PRKG1	S357	R350W	350	Missense	distal	-7	no	15.265	13.500	EPSD	TCGA;ICGC;COSMIC	7.092	Down-regulation
AGC_PKG_PRKG1_ST	Q9Y613	FHOD1	Q13976	PRKG1	S357	R351Q	351	Missense	distal	-6	no	15.265	14.968	EPSD	TCGA;ICGC;COSMIC	7.092	Down-regulation
AGC_PKG_PRKG1_ST	Q9Y613	FHOD1	Q13976	PRKG1	S357	R354Q	354	Missense	distal	-3	no	15.265	11.430	EPSD	TCGA;ICGC;COSMIC	7.092	Down-regulation
AGC_PKG_PRKG1_ST	Q9Y613	FHOD1	Q13976	PRKG1	S358	R351Q	351	Missense	distal	-7	no	7.757	7.080	EPSD	TCGA;ICGC;COSMIC	7.092	Loss
AGC_PKG_PRKG1_ST	Q9Y613	FHOD1	Q13976	PRKG1	S358	R365H	365	Missense	distal	7	no	7.757	7.673	EPSD	TCGA;ICGC;COSMIC	7.092	Down-regulation
AGC_PKG_PRKG1_ST	Q9Y613	FHOD1	Q13976	PRKG1	S358	R354Q	354	Missense	distal	-4	no	7.757	7.361	EPSD	TCGA;ICGC;COSMIC	7.092	Down-regulation
AGC_PKG_PRKG1_ST	Q9Y613	FHOD1	Q13976	PRKG1	S364	G370D	370	Missense	distal	6	no	8.240	8.329	EPSD	TCGA;ICGC;COSMIC	7.092	Up-regulation
AGC_PKG_PRKG1_ST	Q9Y613	FHOD1	Q13976	PRKG1	S364	R365H	365	Missense	proximal	1	no	8.240	7.904	EPSD	TCGA;ICGC;COSMIC	7.092	Down-regulation
AGC_PKG_PRKG1_ST	Q9Y613	FHOD1	Q13976	PRKG1	S364	R366C	366	Missense	proximal	2	no	8.240	8.171	EPSD	TCGA;ICGC;COSMIC	7.092	Down-regulation
AGC_PKG_PRKG1_ST	Q9Y613	FHOD1	Q13976	PRKG1	S364	R366H	366	Missense	proximal	2	no	8.240	8.198	EPSD	TCGA;ICGC;COSMIC	7.092	Down-regulation
AGC_PKG_PRKG1_ST	Q9Y613	FHOD1	Q13976	PRKG1	S367	G370D	370	Missense	distal	3	no	8.047	8.089	EPSD	TCGA;ICGC;COSMIC	7.092	Up-regulation
AGC_PKG_PRKG1_ST	Q9Y613	FHOD1	Q13976	PRKG1	S367	R365H	365	Missense	proximal	-2	no	8.047	3.789	EPSD	TCGA;ICGC;COSMIC	7.092	Loss
AGC_PKG_PRKG1_ST	Q9Y613	FHOD1	Q13976	PRKG1	S367	R366C	366	Missense	proximal	-1	no	8.047	7.845	EPSD	TCGA;ICGC;COSMIC	7.092	Down-regulation
AGC_PKG_PRKG1_ST	Q9Y613	FHOD1	Q13976	PRKG1	S367	R366H	366	Missense	proximal	-1	no	8.047	7.899	EPSD	TCGA;ICGC;COSMIC	7.092	Down-regulation
AGC_PKG_PRKG1_ST	Q9Y613	FHOD1	Q13976	PRKG1	T465	A469T	469	Missense	distal	4	no	7.320	7.323	EPSD	TCGA;ICGC;COSMIC	7.092	Up-regulation
AGC_PKG_PRKG1_ST	Q9Y613	FHOD1	Q13976	PRKG1	S540	P537H	537	Missense	distal	-3	no	8.772	7.606	EPSD	TCGA;ICGC	7.092	Down-regulation
AGC_PKG_PRKG1_ST	Q9Y613	FHOD1	Q13976	PRKG1	S540	L539F	539	Missense	proximal	-1	no	8.772	8.879	EPSD	TCGA;ICGC;COSMIC;CCLE	7.092	Up-regulation
AGC_PKG_PRKG1_ST	Q9Y613	FHOD1	Q13976	PRKG1	T690	P697S	697	Missense	distal	7	no	7.418	7.521	EPSD	TCGA;ICGC;COSMIC	7.092	Up-regulation
AGC_PKG_PRKG1_ST	Q9Y613	FHOD1	Q13976	PRKG1	T692	P697S	697	Missense	distal	5	no	8.640	8.712	EPSD	TCGA;ICGC;COSMIC	7.092	Up-regulation
AGC_PKG_PRKG1_ST	Q9Y613	FHOD1	Q13976	PRKG1	S874	S875C	875	Missense	proximal	1	no	8.367	8.093	EPSD	TCGA;ICGC;COSMIC	7.092	Down-regulation
AGC_PKG_PRKG1_ST	Q9Y613	FHOD1	Q13976	PRKG1	S874	P872R	872	Missense	proximal	-2	no	8.367	12.126	EPSD	TCGA;ICGC;COSMIC	7.092	Up-regulation
AGC_PKG_PRKG1_ST	Q9Y613	FHOD1	Q13976	PRKG1	S874	S875F	875	Missense	proximal	1	no	8.367	8.129	EPSD	TCGA;ICGC;COSMIC	7.092	Down-regulation
AGC_PKG_PRKG1_ST	Q9Y613	FHOD1	Q13976	PRKG1	T1016	E1019K	1019	Missense	distal	3	no	8.271	8.097	EPSD	TCGA;ICGC;COSMIC	7.092	Down-regulation
AGC_PKG_PRKG1_ST	Q9Y613	FHOD1	Q13976	PRKG1	S1131	R1132H	1132	Missense	proximal	1	no	11.398	11.062	PhosphoSitePlus	TCGA;ICGC;COSMIC	7.092	Down-regulation
AGC_PKG_PRKG1_ST	Q9Y613	FHOD1	Q13976	PRKG1	S1131	R1128C	1128	Missense	distal	-3	no	11.398	4.376	PhosphoSitePlus	TCGA;ICGC;COSMIC	7.092	Loss
AGC_PKG_PRKG1_ST	Q9Y613	FHOD1	Q13976	PRKG1	S1131	R1135C	1135	Missense	distal	4	no	11.398	11.558	PhosphoSitePlus	TCGA;ICGC;COSMIC	7.092	Up-regulation
AGC_PKG_PRKG1_ST	Q9Y613	FHOD1	Q13976	PRKG1	S1131	R1132C	1132	Missense	proximal	1	no	11.398	10.949	PhosphoSitePlus	TCGA;ICGC	7.092	Down-regulation
AGC_PKG_PRKG1_ST	Q9Y613	FHOD1	Q13976	PRKG1	S1137	T1141M	1141	Missense	distal	4	no	8.446	8.464	EPSD	TCGA;ICGC;COSMIC	7.092	Up-regulation
AGC_PKG_PRKG1_ST	Q9Y613	FHOD1	Q13976	PRKG1	S1137	L1142F	1142	Missense	distal	5	no	8.446	8.515	EPSD	TCGA;ICGC;COSMIC	7.092	Up-regulation
AGC_PKG_PRKG1_ST	Q9Y613	FHOD1	Q13976	PRKG1	S1137	R1132H	1132	Missense	distal	-5	no	8.446	8.648	EPSD	TCGA;ICGC;COSMIC	7.092	Up-regulation
AGC_PKG_PRKG1_ST	Q9Y613	FHOD1	Q13976	PRKG1	S1137	R1135C	1135	Missense	proximal	-2	no	8.446	3.717	EPSD	TCGA;ICGC;COSMIC	7.092	Loss
AGC_PKG_PRKG1_ST	Q9Y613	FHOD1	Q13976	PRKG1	S1137	R1132C	1132	Missense	distal	-5	no	8.446	8.702	EPSD	TCGA;ICGC	7.092	Up-regulation
AGC_PKG_PRKG1_ST	P78347	GTF2I	Q13976	PRKG1	S95	K94T	94	Missense	proximal	-1	no	7.447	7.403	EPSD	TCGA;ICGC;COSMIC	7.092	Down-regulation
AGC_PKG_PRKG1_ST	P78347	GTF2I	Q13976	PRKG1	S95	S95Y	95	Missense	central	0	yes	7.447	0.000	EPSD	TCGA;ICGC	7.092	Loss
AGC_PKG_PRKG1_ST	P78347	GTF2I	Q13976	PRKG1	S146	R143Q	143	Missense	distal	-3	no	8.106	4.271	EPSD	TCGA;ICGC;COSMIC	7.092	Loss
AGC_PKG_PRKG1_ST	P78347	GTF2I	Q13976	PRKG1	T622	R619Q	619	Missense	distal	-3	no	7.948	4.113	EPSD	TCGA;COSMIC	7.092	Loss
AGC_PKG_PRKG1_ST	P78347	GTF2I	Q13976	PRKG1	T622	P617S	617	Missense	distal	-5	no	7.948	7.833	EPSD	TCGA;COSMIC	7.092	Down-regulation
AGC_PKG_PRKG1_ST	P78347	GTF2I	Q13976	PRKG1	S636	V633I	633	Missense	distal	-3	no	7.184	4.358	EPSD	TCGA;COSMIC;GDSC	7.092	Loss
AGC_PKG_PRKG1_ST	Q14847	LASP1	Q13976	PRKG1	S61	V65L	65	Missense	distal	4	no	7.442	7.534	EPSD	TCGA;ICGC;COSMIC	7.092	Up-regulation
AGC_PKG_PRKG1_ST	Q14847	LASP1	Q13976	PRKG1	S61	A55V	55	Missense	distal	-6	no	7.442	7.106	EPSD	TCGA;COSMIC	7.092	Down-regulation
AGC_PKG_PRKG1_ST	Q14847	LASP1	Q13976	PRKG1	S99	P105S	105	Missense	distal	6	no	7.566	7.331	EPSD	TCGA;ICGC;COSMIC	7.092	Down-regulation
AGC_PKG_PRKG1_ST	Q14847	LASP1	Q13976	PRKG1	S146	M139V	139	Missense	distal	-7	no	12.899	12.293	PhosphoSitePlus	TCGA;ICGC;COSMIC	7.092	Down-regulation
AGC_PKG_PRKG1_ST	Q96A00	PPP1R14A	Q13976	PRKG1	S128	P129T	129	Missense	proximal	1	no	8.666	8.877	EPSD	TCGA;COSMIC	7.092	Up-regulation
AGC_PKG_PRKG1_ST	Q13507	TRPC3	Q13976	PRKG1	S251	K255N	255	Missense	distal	4	no	12.182	12.258	EPSD;PhosphoSitePlus	TCGA;COSMIC	7.092	Up-regulation
AGC_PKG_PRKG1_ST	Q684P5	RAP1GAP2	Q13976	PRKG1	S7	R4Q	4	Missense	distal	-3	no	11.498	7.664	PhosphoSitePlus	TCGA;ICGC;COSMIC	7.092	Down-regulation
AGC_PKG_PRKG1_ST	Q684P5	RAP1GAP2	Q13976	PRKG1	S7	G3S	3	Missense	distal	-4	no	11.498	11.711	PhosphoSitePlus	TCGA;ICGC;COSMIC	7.092	Up-regulation
AGC_PKG_PRKG1_ST	Q684P5	RAP1GAP2	Q13976	PRKG1	S7	G14R	14	Missense	distal	7	no	11.498	11.611	PhosphoSitePlus	TCGA;ICGC	7.092	Up-regulation
AGC_PKG_PRKG1_ST	Q684P5	RAP1GAP2	Q13976	PRKG1	S9	R4Q	4	Missense	distal	-5	no	10.185	10.305	EPSD	TCGA;ICGC;COSMIC	7.092	Up-regulation
AGC_PKG_PRKG1_ST	Q684P5	RAP1GAP2	Q13976	PRKG1	S9	G3S	3	Missense	distal	-6	no	10.185	10.402	EPSD	TCGA;ICGC;COSMIC	7.092	Up-regulation
AGC_PKG_PRKG1_ST	Q684P5	RAP1GAP2	Q13976	PRKG1	S9	G14R	14	Missense	distal	5	no	10.185	10.261	EPSD	TCGA;ICGC	7.092	Up-regulation
AGC_PKG_PRKG1_ST	Q684P5	RAP1GAP2	Q13976	PRKG1	S45	A50S	50	Missense	distal	5	no	10.367	10.382	EPSD	TCGA;ICGC	7.092	Up-regulation
AGC_PKG_PRKG1_ST	Q684P5	RAP1GAP2	Q13976	PRKG1	S57	F59L	59	Missense	proximal	2	no	8.283	8.217	EPSD	TCGA;ICGC;COSMIC	7.092	Down-regulation
AGC_PKG_PRKG1_ST	Q684P5	RAP1GAP2	Q13976	PRKG1	S57	A50S	50	Missense	distal	-7	no	8.283	8.442	EPSD	TCGA;ICGC	7.092	Up-regulation
AGC_PKG_PRKG1_ST	Q684P5	RAP1GAP2	Q13976	PRKG1	S505	R504H	504	Missense	proximal	-1	no	9.649	9.501	EPSD	TCGA;ICGC;COSMIC	7.092	Down-regulation
AGC_PKG_PRKG1_ST	Q684P5	RAP1GAP2	Q13976	PRKG1	S507	R504H	504	Missense	distal	-3	no	9.266	3.199	EPSD	TCGA;ICGC;COSMIC	7.092	Loss
AGC_PKG_PRKG1_ST	Q684P5	RAP1GAP2	Q13976	PRKG1	S518	P524S	524	Missense	distal	6	no	9.982	9.746	EPSD	TCGA;ICGC;COSMIC	7.092	Down-regulation
AGC_PKG_PRKG1_ST	Q684P5	RAP1GAP2	Q13976	PRKG1	S520	P524S	524	Missense	distal	4	no	8.974	8.823	EPSD	TCGA;ICGC;COSMIC	7.092	Down-regulation
AGC_PKG_PRKG1_ST	Q684P5	RAP1GAP2	Q13976	PRKG1	S556	R562Q	562	Missense	distal	6	no	7.102	7.172	EPSD	TCGA;ICGC;COSMIC;CCLE	7.092	Up-regulation
AGC_PKG_PRKG1_ST	Q684P5	RAP1GAP2	Q13976	PRKG1	S556	P559L	559	Missense	distal	3	no	7.102	7.220	EPSD	TCGA;ICGC;COSMIC	7.092	Up-regulation
AGC_PKG_PRKG1_ST	Q684P5	RAP1GAP2	Q13976	PRKG1	S556	V552M	552	Missense	distal	-4	no	7.102	7.499	EPSD	TCGA;ICGC;COSMIC	7.092	Up-regulation
AGC_PKG_PRKG1_ST	Q684P5	RAP1GAP2	Q13976	PRKG1	S556	R563H	563	Missense	distal	7	no	7.102	7.018	EPSD	TCGA;ICGC;COSMIC	7.092	Loss
AGC_PKG_PRKG1_ST	Q684P5	RAP1GAP2	Q13976	PRKG1	S556	S556P	556	Missense	central	0	yes	7.102	0.000	EPSD	TCGA;ICGC;COSMIC	7.092	Loss
AGC_PKG_PRKG1_ST	Q684P5	RAP1GAP2	Q13976	PRKG1	S564	R562Q	562	Missense	proximal	-2	no	13.411	10.446	EPSD	TCGA;ICGC;COSMIC;CCLE	7.092	Down-regulation
AGC_PKG_PRKG1_ST	Q684P5	RAP1GAP2	Q13976	PRKG1	S564	P559L	559	Missense	distal	-5	no	13.411	13.532	EPSD	TCGA;ICGC;COSMIC	7.092	Up-regulation
AGC_PKG_PRKG1_ST	Q684P5	RAP1GAP2	Q13976	PRKG1	S564	S564L	564	Missense	central	0	yes	13.411	0.000	EPSD	TCGA;ICGC;COSMIC	7.092	Loss
AGC_PKG_PRKG1_ST	Q684P5	RAP1GAP2	Q13976	PRKG1	S564	R563H	563	Missense	proximal	-1	no	13.411	13.263	EPSD	TCGA;ICGC;COSMIC	7.092	Down-regulation
AGC_PKG_PRKG1_ST	Q684P5	RAP1GAP2	Q13976	PRKG1	S586	R581W	581	Missense	distal	-5	no	7.714	8.038	EPSD	TCGA;ICGC;COSMIC	7.092	Up-regulation
AGC_PKG_PRKG1_ST	Q684P5	RAP1GAP2	Q13976	PRKG1	S638	G631S	631	Missense	distal	-7	no	7.581	8.098	EPSD	TCGA;ICGC;COSMIC	7.092	Up-regulation
AGC_PKG_PRKG1_ST	Q684P5	RAP1GAP2	Q13976	PRKG1	S638	S635A	635	Missense	distal	-3	no	7.581	8.491	EPSD	TCGA;ICGC;COSMIC	7.092	Up-regulation
AGC_PKG_PRKG1_ST	Q684P5	RAP1GAP2	Q13976	PRKG1	S639	S635A	635	Missense	distal	-4	no	12.053	12.049	EPSD	TCGA;ICGC;COSMIC	7.092	Down-regulation
AGC_PKG_PRKG1_ST	Q684P5	RAP1GAP2	Q13976	PRKG1	T702	S709F	709	Missense	distal	7	no	7.846	7.771	EPSD	TCGA;ICGC;COSMIC	7.092	Down-regulation
AGC_PKG_PRKG1_ST	Q8WZ42	TTN	Q13976	PRKG1	S79	Y78C	78	Missense	proximal	-1	no	10.417	10.409	EPSD	TCGA;ICGC;COSMIC	7.092	Down-regulation
AGC_PKG_PRKG1_ST	Q8WZ42	TTN	Q13976	PRKG1	S79	N74K	74	Missense	distal	-5	no	10.417	10.277	EPSD	TCGA;ICGC	7.092	Down-regulation
AGC_PKG_PRKG1_ST	Q8WZ42	TTN	Q13976	PRKG1	S79	S86C	86	Missense	distal	7	no	10.417	10.344	EPSD	TCGA;ICGC;COSMIC	7.092	Down-regulation
AGC_PKG_PRKG1_ST	Q8WZ42	TTN	Q13976	PRKG1	S79	S79F	79	Missense	central	0	yes	10.417	0.000	EPSD	TCGA;ICGC;COSMIC	7.092	Loss
AGC_PKG_PRKG1_ST	Q8WZ42	TTN	Q13976	PRKG1	S79	R77Q	77	Missense	proximal	-2	no	10.417	7.452	EPSD	TCGA;ICGC;COSMIC	7.092	Down-regulation
AGC_PKG_PRKG1_ST	Q8WZ42	TTN	Q13976	PRKG1	S112	R109Q	109	Missense	distal	-3	no	9.072	5.237	EPSD	TCGA;ICGC;COSMIC	7.092	Loss
AGC_PKG_PRKG1_ST	Q8WZ42	TTN	Q13976	PRKG1	S112	S119I	119	Missense	distal	7	no	9.072	8.925	EPSD	TCGA;ICGC;COSMIC	7.092	Down-regulation
AGC_PKG_PRKG1_ST	Q8WZ42	TTN	Q13976	PRKG1	S263	P258L	258	Missense	distal	-5	no	8.914	9.035	EPSD	TCGA;ICGC;COSMIC	7.092	Up-regulation
AGC_PKG_PRKG1_ST	Q8WZ42	TTN	Q13976	PRKG1	S263	S263L	263	Missense	central	0	yes	8.914	0.000	EPSD	TCGA;ICGC;COSMIC	7.092	Loss
AGC_PKG_PRKG1_ST	Q8WZ42	TTN	Q13976	PRKG1	S263	S265F	265	Missense	proximal	2	no	8.914	8.837	EPSD	TCGA;ICGC;COSMIC	7.092	Down-regulation
AGC_PKG_PRKG1_ST	Q8WZ42	TTN	Q13976	PRKG1	S263	P269L	269	Missense	distal	6	no	8.914	9.042	EPSD	TCGA;ICGC;COSMIC	7.092	Up-regulation
AGC_PKG_PRKG1_ST	Q8WZ42	TTN	Q13976	PRKG1	S263	K260Q	260	Missense	distal	-3	no	8.914	7.437	EPSD	TCGA;ICGC	7.092	Down-regulation
AGC_PKG_PRKG1_ST	Q8WZ42	TTN	Q13976	PRKG1	S265	P258L	258	Missense	distal	-7	no	8.050	7.434	EPSD	TCGA;ICGC;COSMIC	7.092	Down-regulation
AGC_PKG_PRKG1_ST	Q8WZ42	TTN	Q13976	PRKG1	S265	S263L	263	Missense	proximal	-2	no	8.050	6.164	EPSD	TCGA;ICGC;COSMIC	7.092	Loss
AGC_PKG_PRKG1_ST	Q8WZ42	TTN	Q13976	PRKG1	S265	S265F	265	Missense	central	0	yes	8.050	0.000	EPSD	TCGA;ICGC;COSMIC	7.092	Loss
AGC_PKG_PRKG1_ST	Q8WZ42	TTN	Q13976	PRKG1	S265	P269L	269	Missense	distal	4	no	8.050	8.149	EPSD	TCGA;ICGC;COSMIC	7.092	Up-regulation
AGC_PKG_PRKG1_ST	Q8WZ42	TTN	Q13976	PRKG1	S265	K260Q	260	Missense	distal	-5	no	8.050	8.077	EPSD	TCGA;ICGC	7.092	Up-regulation
AGC_PKG_PRKG1_ST	Q8WZ42	TTN	Q13976	PRKG1	T267	S263L	263	Missense	distal	-4	no	9.069	8.296	EPSD	TCGA;ICGC;COSMIC	7.092	Down-regulation
AGC_PKG_PRKG1_ST	Q8WZ42	TTN	Q13976	PRKG1	T267	S265F	265	Missense	proximal	-2	no	9.069	8.307	EPSD	TCGA;ICGC;COSMIC	7.092	Down-regulation
AGC_PKG_PRKG1_ST	Q8WZ42	TTN	Q13976	PRKG1	T267	P269L	269	Missense	proximal	2	no	9.069	9.024	EPSD	TCGA;ICGC;COSMIC	7.092	Down-regulation
AGC_PKG_PRKG1_ST	Q8WZ42	TTN	Q13976	PRKG1	T267	K260Q	260	Missense	distal	-7	no	9.069	8.858	EPSD	TCGA;ICGC	7.092	Down-regulation
AGC_PKG_PRKG1_ST	Q8WZ42	TTN	Q13976	PRKG1	S282	A275S	275	Missense	distal	-7	no	10.144	10.303	EPSD	TCGA;ICGC;COSMIC	7.092	Up-regulation
AGC_PKG_PRKG1_ST	Q8WZ42	TTN	Q13976	PRKG1	S282	R279Q	279	Missense	distal	-3	no	10.144	6.309	EPSD	TCGA;ICGC;COSMIC	7.092	Loss
AGC_PKG_PRKG1_ST	Q8WZ42	TTN	Q13976	PRKG1	S282	S282Y	282	Missense	central	0	yes	10.144	0.000	EPSD	TCGA;ICGC;COSMIC	7.092	Loss
AGC_PKG_PRKG1_ST	Q8WZ42	TTN	Q13976	PRKG1	S282	S284L	284	Missense	proximal	2	no	10.144	10.001	EPSD	TCGA;ICGC;COSMIC	7.092	Down-regulation
AGC_PKG_PRKG1_ST	Q8WZ42	TTN	Q13976	PRKG1	T300	P299L	299	Missense	proximal	-1	no	8.818	8.720	EPSD	TCGA;ICGC;COSMIC	7.092	Down-regulation
AGC_PKG_PRKG1_ST	Q8WZ42	TTN	Q13976	PRKG1	T300	R297W	297	Missense	distal	-3	no	8.818	1.145	EPSD	TCGA;ICGC;COSMIC	7.092	Loss
AGC_PKG_PRKG1_ST	Q8WZ42	TTN	Q13976	PRKG1	T300	R305K	305	Missense	distal	5	no	8.818	8.799	EPSD	TCGA;ICGC;COSMIC;GDSC	7.092	Down-regulation
AGC_PKG_PRKG1_ST	Q8WZ42	TTN	Q13976	PRKG1	T300	P301L	301	Missense	proximal	1	no	8.818	8.588	EPSD	TCGA;ICGC;COSMIC	7.092	Down-regulation
AGC_PKG_PRKG1_ST	Q8WZ42	TTN	Q13976	PRKG1	T300	T300A	300	Missense	central	0	yes	8.818	0.000	EPSD	TCGA;ICGC;COSMIC	7.092	Loss
AGC_PKG_PRKG1_ST	Q8WZ42	TTN	Q13976	PRKG1	S308	R312G	312	Missense	distal	4	no	9.833	9.979	EPSD	TCGA;ICGC;COSMIC	7.092	Up-regulation
AGC_PKG_PRKG1_ST	Q8WZ42	TTN	Q13976	PRKG1	S308	R305K	305	Missense	distal	-3	no	9.833	7.475	EPSD	TCGA;ICGC;COSMIC;GDSC	7.092	Down-regulation
AGC_PKG_PRKG1_ST	Q8WZ42	TTN	Q13976	PRKG1	S308	A310T	310	Missense	proximal	2	no	9.833	9.825	EPSD	TCGA;ICGC;COSMIC	7.092	Down-regulation
AGC_PKG_PRKG1_ST	Q8WZ42	TTN	Q13976	PRKG1	S308	P301L	301	Missense	distal	-7	no	9.833	9.217	EPSD	TCGA;ICGC;COSMIC	7.092	Down-regulation
AGC_PKG_PRKG1_ST	Q8WZ42	TTN	Q13976	PRKG1	S314	R312G	312	Missense	proximal	-2	no	8.828	5.341	EPSD	TCGA;ICGC;COSMIC	7.092	Loss
AGC_PKG_PRKG1_ST	Q8WZ42	TTN	Q13976	PRKG1	S314	A310T	310	Missense	distal	-4	no	8.828	8.714	EPSD	TCGA;ICGC;COSMIC	7.092	Down-regulation
AGC_PKG_PRKG1_ST	Q8WZ42	TTN	Q13976	PRKG1	T330	L326F	326	Missense	distal	-4	no	7.819	8.146	EPSD	TCGA;ICGC;COSMIC	7.092	Up-regulation
AGC_PKG_PRKG1_ST	Q8WZ42	TTN	Q13976	PRKG1	T330	K329N	329	Missense	proximal	-1	no	7.819	7.693	EPSD	TCGA;ICGC;COSMIC	7.092	Down-regulation
AGC_PKG_PRKG1_ST	Q8WZ42	TTN	Q13976	PRKG1	T330	R328H	328	Missense	proximal	-2	no	7.819	3.562	EPSD	TCGA;ICGC;COSMIC	7.092	Loss
AGC_PKG_PRKG1_ST	Q8WZ42	TTN	Q13976	PRKG1	S540	E541K	541	Missense	proximal	1	no	8.164	8.471	EPSD	TCGA;ICGC;COSMIC	7.092	Up-regulation
AGC_PKG_PRKG1_ST	Q8WZ42	TTN	Q13976	PRKG1	S540	E534D	534	Missense	distal	-6	no	8.164	8.020	EPSD	TCGA;ICGC;COSMIC	7.092	Down-regulation
AGC_PKG_PRKG1_ST	Q8WZ42	TTN	Q13976	PRKG1	S540	I539V	539	Missense	proximal	-1	no	8.164	8.251	EPSD	TCGA;ICGC;COSMIC	7.092	Up-regulation
AGC_PKG_PRKG1_ST	Q8WZ42	TTN	Q13976	PRKG1	S540	E536K	536	Missense	distal	-4	no	8.164	8.825	EPSD	TCGA;ICGC;COSMIC	7.092	Up-regulation
AGC_PKG_PRKG1_ST	Q8WZ42	TTN	Q13976	PRKG1	S540	E534Q	534	Missense	distal	-6	no	8.164	8.513	EPSD	TCGA;ICGC;COSMIC	7.092	Up-regulation
AGC_PKG_PRKG1_ST	Q8WZ42	TTN	Q13976	PRKG1	S742	A743T	743	Missense	proximal	1	no	7.300	7.262	EPSD	TCGA;ICGC;COSMIC;CCLE	7.092	Down-regulation
AGC_PKG_PRKG1_ST	Q8WZ42	TTN	Q13976	PRKG1	S742	G736R	736	Missense	distal	-6	no	7.300	7.814	EPSD	TCGA;ICGC;COSMIC;GDSC;CCLE	7.092	Up-regulation
AGC_PKG_PRKG1_ST	Q8WZ42	TTN	Q13976	PRKG1	S742	E739K	739	Missense	distal	-3	no	7.300	11.883	EPSD	TCGA;ICGC;COSMIC	7.092	Up-regulation
AGC_PKG_PRKG1_ST	Q8WZ42	TTN	Q13976	PRKG1	S755	H758D	758	Missense	distal	3	no	8.887	9.001	EPSD	TCGA;ICGC;COSMIC	7.092	Up-regulation
AGC_PKG_PRKG1_ST	Q8WZ42	TTN	Q13976	PRKG1	T795	D796N	796	Missense	proximal	1	no	7.363	7.494	EPSD	TCGA;ICGC;COSMIC;CCLE	7.092	Up-regulation
AGC_PKG_PRKG1_ST	Q8WZ42	TTN	Q13976	PRKG1	T795	D796Y	796	Missense	proximal	1	no	7.363	7.395	EPSD	TCGA;ICGC	7.092	Up-regulation
AGC_PKG_PRKG1_ST	Q8WZ42	TTN	Q13976	PRKG1	T795	T795A	795	Missense	central	0	yes	7.363	0.000	EPSD	TCGA;ICGC;COSMIC	7.092	Loss
AGC_PKG_PRKG1_ST	Q8WZ42	TTN	Q13976	PRKG1	T795	T799M	799	Missense	distal	4	no	7.363	7.381	EPSD	TCGA;ICGC;COSMIC;CCLE	7.092	Up-regulation
AGC_PKG_PRKG1_ST	Q8WZ42	TTN	Q13976	PRKG1	T795	K792E	792	Missense	distal	-3	no	7.363	2.780	EPSD	TCGA;ICGC;COSMIC	7.092	Loss
AGC_PKG_PRKG1_ST	Q8WZ42	TTN	Q13976	PRKG1	T811	R810H	810	Missense	proximal	-1	no	7.914	7.765	EPSD	TCGA;ICGC;COSMIC	7.092	Down-regulation
AGC_PKG_PRKG1_ST	Q8WZ42	TTN	Q13976	PRKG1	T811	R808C	808	Missense	distal	-3	no	7.914	0.891	EPSD	TCGA;ICGC;COSMIC	7.092	Loss
AGC_PKG_PRKG1_ST	Q8WZ42	TTN	Q13976	PRKG1	T811	S813C	813	Missense	proximal	2	no	7.914	7.833	EPSD	TCGA;ICGC;COSMIC	7.092	Down-regulation
AGC_PKG_PRKG1_ST	Q8WZ42	TTN	Q13976	PRKG1	T811	H804L	804	Missense	distal	-7	no	7.914	7.072	EPSD	TCGA;ICGC;COSMIC	7.092	Loss
AGC_PKG_PRKG1_ST	Q8WZ42	TTN	Q13976	PRKG1	T811	T811A	811	Missense	central	0	yes	7.914	0.000	EPSD	TCGA;ICGC;COSMIC	7.092	Loss
AGC_PKG_PRKG1_ST	Q8WZ42	TTN	Q13976	PRKG1	T811	R810C	810	Missense	proximal	-1	no	7.914	7.712	EPSD	TCGA;ICGC;COSMIC	7.092	Down-regulation
AGC_PKG_PRKG1_ST	Q8WZ42	TTN	Q13976	PRKG1	S813	R810H	810	Missense	distal	-3	no	8.560	2.493	EPSD	TCGA;ICGC;COSMIC	7.092	Loss
AGC_PKG_PRKG1_ST	Q8WZ42	TTN	Q13976	PRKG1	S813	R808C	808	Missense	distal	-5	no	8.560	8.816	EPSD	TCGA;ICGC;COSMIC	7.092	Up-regulation
AGC_PKG_PRKG1_ST	Q8WZ42	TTN	Q13976	PRKG1	S813	S813C	813	Missense	central	0	yes	8.560	0.000	EPSD	TCGA;ICGC;COSMIC	7.092	Loss
AGC_PKG_PRKG1_ST	Q8WZ42	TTN	Q13976	PRKG1	S813	T811A	811	Missense	proximal	-2	no	8.560	8.696	EPSD	TCGA;ICGC;COSMIC	7.092	Up-regulation
AGC_PKG_PRKG1_ST	Q8WZ42	TTN	Q13976	PRKG1	S813	R810C	810	Missense	distal	-3	no	8.560	1.538	EPSD	TCGA;ICGC;COSMIC	7.092	Loss
AGC_PKG_PRKG1_ST	Q8WZ42	TTN	Q13976	PRKG1	S847	K854N	854	Missense	distal	7	no	7.475	7.419	EPSD	TCGA;ICGC;COSMIC	7.092	Down-regulation
AGC_PKG_PRKG1_ST	Q8WZ42	TTN	Q13976	PRKG1	S847	A848T	848	Missense	proximal	1	no	7.475	7.437	EPSD	TCGA;ICGC;COSMIC	7.092	Down-regulation
AGC_PKG_PRKG1_ST	Q8WZ42	TTN	Q13976	PRKG1	S847	S851F	851	Missense	distal	4	no	7.475	7.603	EPSD	TCGA;ICGC;COSMIC	7.092	Up-regulation
AGC_PKG_PRKG1_ST	Q8WZ42	TTN	Q13976	PRKG1	S851	K854N	854	Missense	distal	3	no	7.471	7.571	EPSD	TCGA;ICGC;COSMIC	7.092	Up-regulation
AGC_PKG_PRKG1_ST	Q8WZ42	TTN	Q13976	PRKG1	S851	A848T	848	Missense	distal	-3	no	7.471	6.884	EPSD	TCGA;ICGC;COSMIC	7.092	Loss
AGC_PKG_PRKG1_ST	Q8WZ42	TTN	Q13976	PRKG1	S851	I855S	855	Missense	distal	4	no	7.471	7.250	EPSD	TCGA;ICGC;COSMIC	7.092	Down-regulation
AGC_PKG_PRKG1_ST	Q8WZ42	TTN	Q13976	PRKG1	S851	S851F	851	Missense	central	0	yes	7.471	0.000	EPSD	TCGA;ICGC;COSMIC	7.092	Loss
AGC_PKG_PRKG1_ST	Q8WZ42	TTN	Q13976	PRKG1	T869	S867R	867	Missense	proximal	-2	no	3.761	7.169	EPSD	TCGA;ICGC	7.092	Gain
AGC_PKG_PRKG1_ST	Q8WZ42	TTN	Q13976	PRKG1	T1233	R1237I	1237	Missense	distal	4	no	7.062	7.319	EPSD	TCGA;ICGC;COSMIC;CCLE	7.092	Gain
AGC_PKG_PRKG1_ST	Q8WZ42	TTN	Q13976	PRKG1	S1348	L1355F	1355	Missense	distal	7	no	7.863	7.955	EPSD	TCGA;ICGC;COSMIC	7.092	Up-regulation
AGC_PKG_PRKG1_ST	Q8WZ42	TTN	Q13976	PRKG1	S1348	R1350H	1350	Missense	proximal	2	no	7.863	7.821	EPSD	TCGA;ICGC;COSMIC;GDSC;CCLE	7.092	Down-regulation
AGC_PKG_PRKG1_ST	Q8WZ42	TTN	Q13976	PRKG1	S1348	D1344Y	1344	Missense	distal	-4	no	7.863	8.065	EPSD	TCGA	7.092	Up-regulation
AGC_PKG_PRKG1_ST	Q8WZ42	TTN	Q13976	PRKG1	S1348	P1352S	1352	Missense	distal	4	no	7.863	7.712	EPSD	TCGA;ICGC;COSMIC	7.092	Down-regulation
AGC_PKG_PRKG1_ST	Q8WZ42	TTN	Q13976	PRKG1	S1348	A1347T	1347	Missense	proximal	-1	no	7.863	7.868	EPSD	TCGA;ICGC;COSMIC;GDSC;CCLE	7.092	Up-regulation
AGC_PKG_PRKG1_ST	Q8WZ42	TTN	Q13976	PRKG1	S1348	R1350C	1350	Missense	proximal	2	no	7.863	7.795	EPSD	TCGA;ICGC;COSMIC;GDSC;CCLE	7.092	Down-regulation
AGC_PKG_PRKG1_ST	Q8WZ42	TTN	Q13976	PRKG1	S1406	R1412G	1412	Missense	distal	6	no	9.812	10.028	EPSD	TCGA;ICGC;COSMIC	7.092	Up-regulation
AGC_PKG_PRKG1_ST	Q8WZ42	TTN	Q13976	PRKG1	S1406	P1407S	1407	Missense	proximal	1	no	9.812	10.074	EPSD	TCGA;ICGC;COSMIC	7.092	Up-regulation
AGC_PKG_PRKG1_ST	Q8WZ42	TTN	Q13976	PRKG1	S1406	S1404F	1404	Missense	proximal	-2	no	9.812	9.050	EPSD	TCGA;ICGC;COSMIC	7.092	Down-regulation
AGC_PKG_PRKG1_ST	Q8WZ42	TTN	Q13976	PRKG1	S1411	R1412G	1412	Missense	proximal	1	no	12.218	11.854	EPSD	TCGA;ICGC;COSMIC	7.092	Down-regulation
AGC_PKG_PRKG1_ST	Q8WZ42	TTN	Q13976	PRKG1	S1411	P1407S	1407	Missense	distal	-4	no	12.218	12.641	EPSD	TCGA;ICGC;COSMIC	7.092	Up-regulation
AGC_PKG_PRKG1_ST	Q8WZ42	TTN	Q13976	PRKG1	S1411	S1404F	1404	Missense	distal	-7	no	12.218	11.573	EPSD	TCGA;ICGC;COSMIC	7.092	Down-regulation
AGC_PKG_PRKG1_ST	Q8WZ42	TTN	Q13976	PRKG1	S1411	R1416H	1416	Missense	distal	5	no	12.218	12.169	EPSD	TCGA;ICGC;COSMIC	7.092	Down-regulation
AGC_PKG_PRKG1_ST	Q8WZ42	TTN	Q13976	PRKG1	S1423	A1425E	1425	Missense	proximal	2	no	9.899	9.846	EPSD	TCGA;ICGC;COSMIC	7.092	Down-regulation
AGC_PKG_PRKG1_ST	Q8WZ42	TTN	Q13976	PRKG1	S1423	R1426K	1426	Missense	distal	3	no	9.899	9.980	EPSD	TCGA;ICGC;COSMIC	7.092	Up-regulation
AGC_PKG_PRKG1_ST	Q8WZ42	TTN	Q13976	PRKG1	S1423	P1429S	1429	Missense	distal	6	no	9.899	9.663	EPSD	TCGA;ICGC;COSMIC	7.092	Down-regulation
AGC_PKG_PRKG1_ST	Q8WZ42	TTN	Q13976	PRKG1	S1423	R1416H	1416	Missense	distal	-7	no	9.899	8.726	EPSD	TCGA;ICGC;COSMIC	7.092	Down-regulation
AGC_PKG_PRKG1_ST	Q8WZ42	TTN	Q13976	PRKG1	S1423	P1419S	1419	Missense	distal	-4	no	9.899	10.322	EPSD	TCGA;ICGC;COSMIC	7.092	Up-regulation
AGC_PKG_PRKG1_ST	Q8WZ42	TTN	Q13976	PRKG1	S1423	R1426S	1426	Missense	distal	3	no	9.899	9.964	EPSD	TCGA;ICGC;COSMIC	7.092	Up-regulation
AGC_PKG_PRKG1_ST	Q8WZ42	TTN	Q13976	PRKG1	S1428	A1425E	1425	Missense	distal	-3	no	11.058	8.696	EPSD	TCGA;ICGC;COSMIC	7.092	Down-regulation
AGC_PKG_PRKG1_ST	Q8WZ42	TTN	Q13976	PRKG1	S1428	R1426K	1426	Missense	proximal	-2	no	11.058	9.581	EPSD	TCGA;ICGC;COSMIC	7.092	Down-regulation
AGC_PKG_PRKG1_ST	Q8WZ42	TTN	Q13976	PRKG1	S1428	P1429S	1429	Missense	proximal	1	no	11.058	11.320	EPSD	TCGA;ICGC;COSMIC	7.092	Up-regulation
AGC_PKG_PRKG1_ST	Q8WZ42	TTN	Q13976	PRKG1	S1428	R1426S	1426	Missense	proximal	-2	no	11.058	7.650	EPSD	TCGA;ICGC;COSMIC	7.092	Down-regulation
AGC_PKG_PRKG1_ST	Q8WZ42	TTN	Q13976	PRKG1	S1428	R1431W	1431	Missense	distal	3	no	11.058	11.375	EPSD	TCGA;ICGC;COSMIC	7.092	Up-regulation
AGC_PKG_PRKG1_ST	Q8WZ42	TTN	Q13976	PRKG1	S1433	P1439H	1439	Missense	distal	6	no	9.496	9.369	EPSD	TCGA;ICGC;COSMIC	7.092	Down-regulation
AGC_PKG_PRKG1_ST	Q8WZ42	TTN	Q13976	PRKG1	S1433	R1426K	1426	Missense	distal	-7	no	9.496	9.030	EPSD	TCGA;ICGC;COSMIC	7.092	Down-regulation
AGC_PKG_PRKG1_ST	Q8WZ42	TTN	Q13976	PRKG1	S1433	G1440E	1440	Missense	distal	7	no	9.496	9.482	EPSD	TCGA;ICGC;COSMIC	7.092	Down-regulation
AGC_PKG_PRKG1_ST	Q8WZ42	TTN	Q13976	PRKG1	S1433	P1429S	1429	Missense	distal	-4	no	9.496	9.919	EPSD	TCGA;ICGC;COSMIC	7.092	Up-regulation
AGC_PKG_PRKG1_ST	Q8WZ42	TTN	Q13976	PRKG1	S1433	R1426S	1426	Missense	distal	-7	no	9.496	8.864	EPSD	TCGA;ICGC;COSMIC	7.092	Down-regulation
AGC_PKG_PRKG1_ST	Q8WZ42	TTN	Q13976	PRKG1	S1433	R1431W	1431	Missense	proximal	-2	no	9.496	4.166	EPSD	TCGA;ICGC;COSMIC	7.092	Loss
AGC_PKG_PRKG1_ST	Q8WZ42	TTN	Q13976	PRKG1	S1438	P1439H	1439	Missense	proximal	1	no	9.145	9.246	EPSD	TCGA;ICGC;COSMIC	7.092	Up-regulation
AGC_PKG_PRKG1_ST	Q8WZ42	TTN	Q13976	PRKG1	S1438	G1440E	1440	Missense	proximal	2	no	9.145	9.138	EPSD	TCGA;ICGC;COSMIC	7.092	Down-regulation
AGC_PKG_PRKG1_ST	Q8WZ42	TTN	Q13976	PRKG1	S1438	R1431W	1431	Missense	distal	-7	no	9.145	7.380	EPSD	TCGA;ICGC;COSMIC	7.092	Down-regulation
AGC_PKG_PRKG1_ST	Q8WZ42	TTN	Q13976	PRKG1	T1473	E1470K	1470	Missense	distal	-3	no	2.724	7.307	EPSD	TCGA;ICGC;COSMIC	7.092	Gain
AGC_PKG_PRKG1_ST	Q8WZ42	TTN	Q13976	PRKG1	S1539	V1543E	1543	Missense	distal	4	no	8.148	8.109	EPSD	TCGA;ICGC;COSMIC	7.092	Down-regulation
AGC_PKG_PRKG1_ST	Q8WZ42	TTN	Q13976	PRKG1	S1539	T1546I	1546	Missense	distal	7	no	8.148	8.013	EPSD	TCGA;ICGC;COSMIC	7.092	Down-regulation
AGC_PKG_PRKG1_ST	Q8WZ42	TTN	Q13976	PRKG1	S1539	S1542L	1542	Missense	distal	3	no	8.148	8.517	EPSD	TCGA;ICGC;COSMIC	7.092	Up-regulation
AGC_PKG_PRKG1_ST	Q8WZ42	TTN	Q13976	PRKG1	S1539	G1537D	1537	Missense	proximal	-2	no	8.148	5.733	EPSD	TCGA;ICGC;COSMIC	7.092	Loss
AGC_PKG_PRKG1_ST	Q8WZ42	TTN	Q13976	PRKG1	S1539	I1544T	1544	Missense	distal	5	no	8.148	8.244	EPSD	TCGA;ICGC;COSMIC	7.092	Up-regulation
AGC_PKG_PRKG1_ST	Q8WZ42	TTN	Q13976	PRKG1	S1539	V1543A	1543	Missense	distal	4	no	8.148	8.009	EPSD	TCGA;ICGC	7.092	Down-regulation
AGC_PKG_PRKG1_ST	Q8WZ42	TTN	Q13976	PRKG1	S1539	R1535M	1535	Missense	distal	-4	no	8.148	7.545	EPSD	TCGA;ICGC;COSMIC	7.092	Down-regulation
AGC_PKG_PRKG1_ST	Q8WZ42	TTN	Q13976	PRKG1	S1540	V1543E	1543	Missense	distal	3	no	8.248	8.211	EPSD	TCGA;ICGC;COSMIC	7.092	Down-regulation
AGC_PKG_PRKG1_ST	Q8WZ42	TTN	Q13976	PRKG1	S1540	T1546I	1546	Missense	distal	6	no	8.248	8.539	EPSD	TCGA;ICGC;COSMIC	7.092	Up-regulation
AGC_PKG_PRKG1_ST	Q8WZ42	TTN	Q13976	PRKG1	S1540	S1542L	1542	Missense	proximal	2	no	8.248	8.105	EPSD	TCGA;ICGC;COSMIC	7.092	Down-regulation
AGC_PKG_PRKG1_ST	Q8WZ42	TTN	Q13976	PRKG1	S1540	G1537D	1537	Missense	distal	-3	no	8.248	4.350	EPSD	TCGA;ICGC;COSMIC	7.092	Loss
AGC_PKG_PRKG1_ST	Q8WZ42	TTN	Q13976	PRKG1	S1540	I1544T	1544	Missense	distal	4	no	8.248	8.050	EPSD	TCGA;ICGC;COSMIC	7.092	Down-regulation
AGC_PKG_PRKG1_ST	Q8WZ42	TTN	Q13976	PRKG1	S1540	V1547M	1547	Missense	distal	7	no	8.248	8.324	EPSD	TCGA;ICGC;COSMIC	7.092	Up-regulation
AGC_PKG_PRKG1_ST	Q8WZ42	TTN	Q13976	PRKG1	S1540	V1543A	1543	Missense	distal	3	no	8.248	8.046	EPSD	TCGA;ICGC	7.092	Down-regulation
AGC_PKG_PRKG1_ST	Q8WZ42	TTN	Q13976	PRKG1	S1540	R1535M	1535	Missense	distal	-5	no	8.248	8.409	EPSD	TCGA;ICGC;COSMIC	7.092	Up-regulation
AGC_PKG_PRKG1_ST	Q8WZ42	TTN	Q13976	PRKG1	S1571	V1565A	1565	Missense	distal	-6	no	6.795	7.131	EPSD	TCGA;ICGC;COSMIC	7.092	Gain
AGC_PKG_PRKG1_ST	Q8WZ42	TTN	Q13976	PRKG1	T1710	F1705L	1705	Missense	distal	-5	no	8.254	8.385	EPSD	TCGA;ICGC;COSMIC;CCLE	7.092	Up-regulation
AGC_PKG_PRKG1_ST	Q8WZ42	TTN	Q13976	PRKG1	T1710	K1706M	1706	Missense	distal	-4	no	8.254	7.956	EPSD	TCGA;ICGC;COSMIC	7.092	Down-regulation
AGC_PKG_PRKG1_ST	Q8WZ42	TTN	Q13976	PRKG1	T1710	R1716H	1716	Missense	distal	6	no	8.254	8.435	EPSD	TCGA;ICGC;COSMIC	7.092	Up-regulation
AGC_PKG_PRKG1_ST	Q8WZ42	TTN	Q13976	PRKG1	T1710	S1711F	1711	Missense	proximal	1	no	8.254	8.015	EPSD	TCGA;ICGC;COSMIC	7.092	Down-regulation
AGC_PKG_PRKG1_ST	Q8WZ42	TTN	Q13976	PRKG1	T1710	R1713G	1713	Missense	distal	3	no	8.254	8.481	EPSD	TCGA;ICGC;COSMIC	7.092	Up-regulation
AGC_PKG_PRKG1_ST	Q8WZ42	TTN	Q13976	PRKG1	T1710	K1707T	1707	Missense	distal	-3	no	8.254	5.447	EPSD	TCGA;ICGC	7.092	Loss
AGC_PKG_PRKG1_ST	Q8WZ42	TTN	Q13976	PRKG1	S2086	E2082K	2082	Missense	distal	-4	no	6.947	7.607	EPSD	TCGA;ICGC;COSMIC;CCLE	7.092	Gain
AGC_PKG_PRKG1_ST	Q8WZ42	TTN	Q13976	PRKG1	T3022	M3016I	3016	Missense	distal	-6	no	7.854	7.333	EPSD	TCGA;ICGC;COSMIC	7.092	Down-regulation
AGC_PKG_PRKG1_ST	Q8WZ42	TTN	Q13976	PRKG1	T3022	N3026K	3026	Missense	distal	4	no	7.854	7.778	EPSD	TCGA;ICGC;COSMIC	7.092	Down-regulation
AGC_PKG_PRKG1_ST	Q8WZ42	TTN	Q13976	PRKG1	T3022	H3023D	3023	Missense	proximal	1	no	7.854	7.680	EPSD	TCGA;ICGC	7.092	Down-regulation
AGC_PKG_PRKG1_ST	Q8WZ42	TTN	Q13976	PRKG1	S3122	G3125R	3125	Missense	distal	3	no	7.720	7.493	EPSD	TCGA;ICGC;COSMIC	7.092	Down-regulation
AGC_PKG_PRKG1_ST	Q8WZ42	TTN	Q13976	PRKG1	S3122	M3121I	3121	Missense	proximal	-1	no	7.720	7.530	EPSD	TCGA;ICGC;COSMIC	7.092	Down-regulation
AGC_PKG_PRKG1_ST	Q8WZ42	TTN	Q13976	PRKG1	S3122	K3126E	3126	Missense	distal	4	no	7.720	7.836	EPSD	TCGA;ICGC;COSMIC	7.092	Up-regulation
AGC_PKG_PRKG1_ST	Q8WZ42	TTN	Q13976	PRKG1	S3122	K3126T	3126	Missense	distal	4	no	7.720	7.738	EPSD	TCGA;ICGC;COSMIC	7.092	Up-regulation
AGC_PKG_PRKG1_ST	Q8WZ42	TTN	Q13976	PRKG1	T3128	G3125R	3125	Missense	distal	-3	no	6.771	11.361	EPSD	TCGA;ICGC;COSMIC	7.092	Gain
AGC_PKG_PRKG1_ST	Q8WZ42	TTN	Q13976	PRKG1	S3228	R3224S	3224	Missense	distal	-4	no	7.664	7.194	EPSD	TCGA;ICGC;COSMIC	7.092	Down-regulation
AGC_PKG_PRKG1_ST	Q8WZ42	TTN	Q13976	PRKG1	S3228	R3224K	3224	Missense	distal	-4	no	7.664	7.359	EPSD	TCGA;ICGC;COSMIC	7.092	Down-regulation
AGC_PKG_PRKG1_ST	Q8WZ42	TTN	Q13976	PRKG1	S3369	S3376L	3376	Missense	distal	7	no	9.084	8.917	EPSD	TCGA;ICGC;COSMIC	7.092	Down-regulation
AGC_PKG_PRKG1_ST	Q8WZ42	TTN	Q13976	PRKG1	S4185	K4183T	4183	Missense	proximal	-2	no	8.004	5.889	PhosphoSitePlus;EPSD	TCGA;COSMIC	7.092	Loss
AGC_PKG_PRKG1_ST	Q8WZ42	TTN	Q13976	PRKG1	S4486	T4489K	4489	Missense	distal	3	no	9.991	10.014	EPSD	TCGA;COSMIC	7.092	Up-regulation
AGC_PKG_PRKG1_ST	Q8WZ42	TTN	Q13976	PRKG1	S6545	V6540I	6540	Missense	distal	-5	no	6.994	7.097	EPSD	TCGA;COSMIC	7.092	Gain
AGC_PKG_PRKG1_ST	Q8WZ42	TTN	Q13976	PRKG1	S7308	E7307K	7307	Missense	proximal	-1	no	8.075	8.236	EPSD	TCGA;ICGC;COSMIC	7.092	Up-regulation
AGC_PKG_PRKG1_ST	Q8WZ42	TTN	Q13976	PRKG1	S7563	G7558V	7558	Missense	distal	-5	no	9.410	9.448	EPSD	TCGA;COSMIC;CCLE	7.092	Up-regulation
AGC_PKG_PRKG1_ST	Q8WZ42	TTN	Q13976	PRKG1	S7563	G7558E	7558	Missense	distal	-5	no	9.410	9.457	EPSD	TCGA	7.092	Up-regulation
AGC_PKG_PRKG1_ST	Q8WZ42	TTN	Q13976	PRKG1	S8740	L8742F	8742	Missense	proximal	2	no	7.356	7.422	EPSD	TCGA;COSMIC	7.092	Up-regulation
AGC_PKG_PRKG1_ST	Q8WZ42	TTN	Q13976	PRKG1	S11223	P11219L	11219	Missense	distal	-4	no	7.439	7.089	EPSD	TCGA;COSMIC;GDSC	7.092	Loss
AGC_PKG_PRKG1_ST	Q8WZ42	TTN	Q13976	PRKG1	S13113	A13107S	13107	Missense	distal	-6	no	7.486	7.530	EPSD	TCGA;COSMIC	7.092	Up-regulation
AGC_PKG_PRKG1_ST	Q8WZ42	TTN	Q13976	PRKG1	T13178	K13175T	13175	Missense	distal	-3	no	7.324	4.516	EPSD	TCGA;COSMIC	7.092	Loss
AGC_PKG_PRKG1_ST	Q8WZ42	TTN	Q13976	PRKG1	T17591	P17592H	17592	Missense	proximal	1	no	8.843	8.944	EPSD	TCGA;COSMIC	7.092	Up-regulation
AGC_PKG_PRKG1_ST	Q8WZ42	TTN	Q13976	PRKG1	T17591	W17590S	17590	Missense	proximal	-1	no	8.843	8.999	EPSD	TCGA;COSMIC	7.092	Up-regulation
AGC_PKG_PRKG1_ST	Q8WZ42	TTN	Q13976	PRKG1	S18166	G18171A	18171	Missense	distal	5	no	8.502	8.541	EPSD	TCGA;COSMIC	7.092	Up-regulation
AGC_PKG_PRKG1_ST	Q8WZ42	TTN	Q13976	PRKG1	S18166	G18171E	18171	Missense	distal	5	no	8.502	8.497	EPSD	TCGA;COSMIC	7.092	Down-regulation
AGC_PKG_PRKG1_ST	Q8WZ42	TTN	Q13976	PRKG1	S19893	S19893L	19893	Missense	central	0	yes	12.669	0.000	EPSD	TCGA;COSMIC	7.092	Loss
AGC_PKG_PRKG1_ST	Q8WZ42	TTN	Q13976	PRKG1	T20132	T20129K	20129	Missense	distal	-3	no	4.363	7.170	EPSD	TCGA;COSMIC	7.092	Gain
AGC_PKG_PRKG1_ST	Q8WZ42	TTN	Q13976	PRKG1	S20205	S20202R	20202	Missense	distal	-3	no	4.265	9.754	EPSD	TCGA;COSMIC	7.092	Gain
AGC_PKG_PRKG1_ST	Q8WZ42	TTN	Q13976	PRKG1	S21216	V21217A	21217	Missense	proximal	1	no	6.897	7.220	EPSD	TCGA;COSMIC	7.092	Gain
AGC_PKG_PRKG1_ST	Q8WZ42	TTN	Q13976	PRKG1	T23210	E23206K	23206	Missense	distal	-4	no	8.444	9.105	EPSD	TCGA;ICGC;COSMIC	7.092	Up-regulation
AGC_PKG_PRKG1_ST	Q8WZ42	TTN	Q13976	PRKG1	S25898	G25896R	25896	Missense	proximal	-2	no	4.101	7.588	EPSD	TCGA;COSMIC	7.092	Gain
AGC_PKG_PRKG1_ST	Q8WZ42	TTN	Q13976	PRKG1	S26971	V26969I	26969	Missense	proximal	-2	no	9.189	7.142	EPSD	TCGA	7.092	Down-regulation
AGC_PKG_PRKG1_ST	Q8WZ42	TTN	Q13976	PRKG1	S27540	L27534R	27534	Missense	distal	-6	no	7.690	8.613	EPSD	TCGA;COSMIC	7.092	Up-regulation
AGC_PKG_PRKG1_ST	Q8WZ42	TTN	Q13976	PRKG1	S27867	L27865I	27865	Missense	proximal	-2	no	7.364	6.653	EPSD	TCGA;COSMIC	7.092	Loss
AGC_PKG_PRKG1_ST	Q8WZ42	TTN	Q13976	PRKG1	S28627	R28624H	28624	Missense	distal	-3	no	8.326	2.259	EPSD	TCGA;COSMIC	7.092	Loss
AGC_PKG_PRKG1_ST	Q8WZ42	TTN	Q13976	PRKG1	S28627	R28624C	28624	Missense	distal	-3	no	8.326	1.304	EPSD	TCGA;COSMIC	7.092	Loss
AGC_PKG_PRKG1_ST	Q8WZ42	TTN	Q13976	PRKG1	S29421	S29418F	29418	Missense	distal	-3	no	10.167	8.979	EPSD	TCGA;COSMIC	7.092	Down-regulation
AGC_PKG_PRKG1_ST	Q8WZ42	TTN	Q13976	PRKG1	S29659	I29665V	29665	Missense	distal	6	no	8.841	8.738	EPSD	TCGA;COSMIC	7.092	Down-regulation
AGC_PKG_PRKG1_ST	Q8WZ42	TTN	Q13976	PRKG1	S29710	Q29716R	29716	Missense	distal	6	no	9.960	9.889	EPSD	TCGA;COSMIC	7.092	Down-regulation
AGC_PKG_PRKG1_ST	Q8WZ42	TTN	Q13976	PRKG1	S30454	K30453T	30453	Missense	proximal	-1	no	7.944	7.900	EPSD	TCGA;COSMIC	7.092	Down-regulation
AGC_PKG_PRKG1_ST	Q8WZ42	TTN	Q13976	PRKG1	T30456	K30453T	30453	Missense	distal	-3	no	7.502	4.694	EPSD	TCGA;COSMIC	7.092	Loss
AGC_PKG_PRKG1_ST	Q8WZ42	TTN	Q13976	PRKG1	S30920	T30921R	30921	Missense	proximal	1	no	8.644	8.869	EPSD	TCGA;COSMIC	7.092	Up-regulation
AGC_PKG_PRKG1_ST	Q8WZ42	TTN	Q13976	PRKG1	T30924	T30921R	30921	Missense	distal	-3	no	4.927	10.092	EPSD	TCGA;COSMIC	7.092	Gain
AGC_PKG_PRKG1_ST	Q8WZ42	TTN	Q13976	PRKG1	S31129	S31129Y	31129	Missense	central	0	yes	9.849	0.000	EPSD	TCGA;COSMIC	7.092	Loss
AGC_PKG_PRKG1_ST	Q8WZ42	TTN	Q13976	PRKG1	S31129	S31129F	31129	Missense	central	0	yes	9.849	0.000	EPSD	TCGA;COSMIC	7.092	Loss
AGC_PKG_PRKG1_ST	Q8WZ42	TTN	Q13976	PRKG1	S31449	L31454F	31454	Missense	distal	5	no	7.134	7.203	EPSD	TCGA;COSMIC	7.092	Up-regulation
AGC_PKG_PRKG1_ST	Q8WZ42	TTN	Q13976	PRKG1	S31456	L31454F	31454	Missense	proximal	-2	no	7.451	8.575	EPSD	TCGA;COSMIC	7.092	Up-regulation
AGC_PKG_PRKG1_ST	Q8WZ42	TTN	Q13976	PRKG1	S33201	L33202P	33202	Missense	proximal	1	no	14.703	14.933	EPSD	TCGA	7.092	Up-regulation
AGC_PKG_PRKG1_ST	Q8WZ42	TTN	Q13976	PRKG1	S33203	L33202P	33202	Missense	proximal	-1	no	9.978	10.075	EPSD	TCGA	7.092	Up-regulation
AGC_PKG_PRKG1_ST	Q8WZ42	TTN	Q13976	PRKG1	S33624	P33625H	33625	Missense	proximal	1	no	7.698	7.798	EPSD	TCGA;COSMIC	7.092	Up-regulation
AGC_PKG_PRKG1_ST	Q8WZ42	TTN	Q13976	PRKG1	S33885	E33886Q	33886	Missense	proximal	1	no	8.568	8.840	EPSD	TCGA;COSMIC	7.092	Up-regulation
AGC_PKG_PRKG1_ST	Q05469	LIPE	Q13976	PRKG1	S200	F206L	206	Missense	distal	6	no	7.726	7.898	EPSD	TCGA;ICGC;COSMIC	7.092	Up-regulation
AGC_PKG_PRKG1_ST	Q05469	LIPE	Q13976	PRKG1	S200	S200Y	200	Missense	central	0	yes	7.726	0.000	EPSD	TCGA;ICGC	7.092	Loss
AGC_PKG_PRKG1_ST	Q05469	LIPE	Q13976	PRKG1	S565	R566H	566	Missense	proximal	1	no	8.424	8.088	EPSD	TCGA;ICGC;COSMIC;GDSC;CCLE	7.092	Down-regulation
AGC_PKG_PRKG1_ST	Q05469	LIPE	Q13976	PRKG1	S645	G652A	652	Missense	distal	7	no	10.165	10.217	EPSD	TCGA;ICGC;COSMIC	7.092	Up-regulation
AGC_PKG_PRKG1_ST	Q05469	LIPE	Q13976	PRKG1	S645	R642H	642	Missense	distal	-3	no	10.165	4.097	EPSD	TCGA;ICGC;COSMIC	7.092	Loss
AGC_PKG_PRKG1_ST	Q05469	LIPE	Q13976	PRKG1	T813	R810Q	810	Missense	distal	-3	no	11.780	7.945	EPSD	TCGA;ICGC;COSMIC;GDSC	7.092	Down-regulation
AGC_PKG_PRKG1_ST	Q05469	LIPE	Q13976	PRKG1	S853	E856K	856	Missense	distal	3	no	9.831	9.658	PhosphoSitePlus	TCGA;ICGC;COSMIC	7.092	Down-regulation
AGC_PKG_PRKG1_ST	Q05469	LIPE	Q13976	PRKG1	S853	P849L	849	Missense	distal	-4	no	9.831	9.481	PhosphoSitePlus	TCGA;ICGC;COSMIC	7.092	Down-regulation
AGC_PKG_PRKG1_ST	Q05469	LIPE	Q13976	PRKG1	S853	R851C	851	Missense	proximal	-2	no	9.831	5.103	PhosphoSitePlus	TCGA;ICGC;COSMIC	7.092	Loss
AGC_PKG_PRKG1_ST	Q05469	LIPE	Q13976	PRKG1	S853	R851H	851	Missense	proximal	-2	no	9.831	5.574	PhosphoSitePlus	TCGA;ICGC;COSMIC	7.092	Loss
AGC_PKG_PRKG1_ST	Q05469	LIPE	Q13976	PRKG1	S855	E856K	856	Missense	proximal	1	no	9.844	10.151	EPSD	TCGA;ICGC;COSMIC	7.092	Up-regulation
AGC_PKG_PRKG1_ST	Q05469	LIPE	Q13976	PRKG1	S855	P849L	849	Missense	distal	-6	no	9.844	9.534	EPSD	TCGA;ICGC;COSMIC	7.092	Down-regulation
AGC_PKG_PRKG1_ST	Q05469	LIPE	Q13976	PRKG1	S855	R851C	851	Missense	distal	-4	no	9.844	8.884	EPSD	TCGA;ICGC;COSMIC	7.092	Down-regulation
AGC_PKG_PRKG1_ST	Q05469	LIPE	Q13976	PRKG1	S855	R851H	851	Missense	distal	-4	no	9.844	9.088	EPSD	TCGA;ICGC;COSMIC	7.092	Down-regulation
AGC_PKG_PRKG1_ST	Q05469	LIPE	Q13976	PRKG1	S880	L879F	879	Missense	proximal	-1	no	6.989	7.096	EPSD	TCGA;ICGC;COSMIC	7.092	Gain
AGC_PKG_PRKG1_ST	Q05469	LIPE	Q13976	PRKG1	S880	L874M	874	Missense	distal	-6	no	6.989	7.500	EPSD	TCGA;ICGC;COSMIC	7.092	Gain
AGC_PKG_PRKG1_ST	Q05469	LIPE	Q13976	PRKG1	S902	E899Q	899	Missense	distal	-3	no	4.142	7.248	EPSD	TCGA;ICGC;COSMIC	7.092	Gain
AGC_PKG_PRKG1_ST	Q05469	LIPE	Q13976	PRKG1	S950	E943K	943	Missense	distal	-7	no	7.217	8.218	EPSD	TCGA;ICGC;COSMIC;GDSC;CCLE	7.092	Up-regulation
AGC_PKG_PRKG1_ST	Q05469	LIPE	Q13976	PRKG1	S950	R949C	949	Missense	proximal	-1	no	7.217	7.015	EPSD	TCGA;ICGC;COSMIC	7.092	Loss
AGC_PKG_PRKG1_ST	Q05469	LIPE	Q13976	PRKG1	S951	R949C	949	Missense	proximal	-2	no	13.709	8.981	EPSD	TCGA;ICGC;COSMIC	7.092	Down-regulation
AGC_PKG_PRKG1_ST	P41220	RGS2	Q13976	PRKG1	S46	R44L	44	Missense	proximal	-2	no	9.681	4.388	PhosphoSitePlus;EPSD	TCGA;ICGC;COSMIC	7.092	Loss
AGC_PKG_PRKG1_ST	P41220	RGS2	Q13976	PRKG1	S46	S46R	46	Missense	central	0	yes	9.681	0.000	PhosphoSitePlus;EPSD	TCGA;ICGC;COSMIC	7.092	Loss
AGC_PKG_PRKG1_ST	P41220	RGS2	Q13976	PRKG1	S46	Q50H	50	Missense	distal	4	no	9.681	9.740	PhosphoSitePlus;EPSD	TCGA;ICGC	7.092	Up-regulation
AGC_PKG_PRKG1_ST	P41220	RGS2	Q13976	PRKG1	S46	S53Y	53	Missense	distal	7	no	9.681	9.597	PhosphoSitePlus;EPSD	TCGA;ICGC;COSMIC	7.092	Down-regulation
AGC_PKG_PRKG1_ST	P41220	RGS2	Q13976	PRKG1	S64	T60I	60	Missense	distal	-4	no	8.464	7.743	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	7.092	Down-regulation
AGC_PKG_PRKG1_ST	P41220	RGS2	Q13976	PRKG1	S179	A173V	173	Missense	distal	-6	no	9.865	9.528	EPSD	TCGA;ICGC	7.092	Down-regulation
AGC_PKG_PRKG1_ST	P48995	TRPC1	Q13976	PRKG1	S206	R213H	213	Missense	distal	7	no	8.180	8.097	EPSD;PhosphoSitePlus	TCGA;ICGC	7.092	Down-regulation
AGC_PKG_PRKG1_ST	P48995	TRPC1	Q13976	PRKG1	S206	K204R	204	Missense	proximal	-2	no	8.180	9.658	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	7.092	Up-regulation
AGC_PKG_PRKG1_ST	P48995	TRPC1	Q13976	PRKG1	S279	R277W	277	Missense	proximal	-2	no	8.294	2.964	EPSD	TCGA;ICGC;COSMIC	7.092	Loss
AGC_PKG_PRKG1_ST	P48995	TRPC1	Q13976	PRKG1	S279	L286V	286	Missense	distal	7	no	8.294	8.368	EPSD	TCGA;ICGC;COSMIC	7.092	Up-regulation
AGC_PKG_PRKG1_ST	P48995	TRPC1	Q13976	PRKG1	S279	E281K	281	Missense	proximal	2	no	8.294	8.345	EPSD	TCGA;ICGC;COSMIC	7.092	Up-regulation
AGC_PKG_PRKG1_ST	P48995	TRPC1	Q13976	PRKG1	T347	G341D	341	Missense	distal	-6	no	10.040	9.766	PhosphoSitePlus;EPSD	TCGA;ICGC;COSMIC	7.092	Down-regulation
AGC_PKG_PRKG1_ST	P48995	TRPC1	Q13976	PRKG1	T347	R344C	344	Missense	distal	-3	no	10.040	3.018	PhosphoSitePlus;EPSD	TCGA;ICGC;COSMIC;CCLE	7.092	Loss
AGC_PKG_PRKG1_ST	P48995	TRPC1	Q13976	PRKG1	T347	R343L	343	Missense	distal	-4	no	10.040	8.797	PhosphoSitePlus;EPSD	TCGA;ICGC;COSMIC	7.092	Down-regulation
AGC_PKG_PRKG1_ST	P48995	TRPC1	Q13976	PRKG1	T347	R344H	344	Missense	distal	-3	no	10.040	3.973	PhosphoSitePlus;EPSD	TCGA;ICGC;COSMIC;CCLE	7.092	Loss
AGC_PKG_PRKG1_ST	P48995	TRPC1	Q13976	PRKG1	T347	Y342H	342	Missense	distal	-5	no	10.040	9.987	PhosphoSitePlus;EPSD	TCGA;ICGC;COSMIC	7.092	Down-regulation
AGC_PKG_PRKG1_ST	P48995	TRPC1	Q13976	PRKG1	T415	A419T	419	Missense	distal	4	no	7.467	7.469	EPSD	TCGA;ICGC;COSMIC	7.092	Up-regulation
AGC_PKG_PRKG1_ST	P48995	TRPC1	Q13976	PRKG1	T415	K412N	412	Missense	distal	-3	no	7.467	2.920	EPSD	TCGA;ICGC;COSMIC	7.092	Loss
AGC_PKG_PRKG1_ST	P48995	TRPC1	Q13976	PRKG1	T415	R422K	422	Missense	distal	7	no	7.467	7.424	EPSD	TCGA;ICGC;COSMIC	7.092	Down-regulation
AGC_PKG_PRKG1_ST	P48995	TRPC1	Q13976	PRKG1	T415	R422I	422	Missense	distal	7	no	7.467	7.281	EPSD	TCGA;ICGC;COSMIC	7.092	Down-regulation
AGC_PKG_PRKG1_ST	P48995	TRPC1	Q13976	PRKG1	S752	M750I	750	Missense	proximal	-2	no	9.284	6.543	EPSD	TCGA;ICGC;COSMIC	7.092	Loss
AGC_PKG_PRKG1_ST	P48995	TRPC1	Q13976	PRKG1	S752	M750T	750	Missense	proximal	-2	no	9.284	8.956	EPSD	TCGA;ICGC;COSMIC	7.092	Down-regulation
AGC_PKG_PRKG1_ST	P48995	TRPC1	Q13976	PRKG1	S752	S745Y	745	Missense	distal	-7	no	9.284	8.494	EPSD	TCGA;ICGC	7.092	Down-regulation
AGC_PKG_PRKG1_ST	P31645	SLC6A4	Q13976	PRKG1	S13	S13L	13	Missense	central	0	yes	8.019	0.000	EPSD	TCGA;ICGC;COSMIC	7.092	Loss
AGC_PKG_PRKG1_ST	P31645	SLC6A4	Q13976	PRKG1	S13	Q9E	9	Missense	distal	-4	no	8.019	7.450	EPSD	TCGA;ICGC;COSMIC	7.092	Down-regulation
AGC_PKG_PRKG1_ST	P31645	SLC6A4	Q13976	PRKG1	S13	S8Y	8	Missense	distal	-5	no	8.019	8.134	EPSD	TCGA;ICGC;COSMIC;GDSC	7.092	Up-regulation
AGC_PKG_PRKG1_ST	P31645	SLC6A4	Q13976	PRKG1	S44	S44P	44	Missense	central	0	yes	7.975	0.000	EPSD	TCGA;ICGC;COSMIC	7.092	Loss
AGC_PKG_PRKG1_ST	P31645	SLC6A4	Q13976	PRKG1	S62	S62F	62	Missense	central	0	yes	8.971	0.000	EPSD	TCGA;ICGC;COSMIC	7.092	Loss
AGC_PKG_PRKG1_ST	P31645	SLC6A4	Q13976	PRKG1	S62	D58N	58	Missense	distal	-4	no	8.971	9.240	EPSD	TCGA;ICGC;COSMIC	7.092	Up-regulation
AGC_PKG_PRKG1_ST	P31645	SLC6A4	Q13976	PRKG1	S62	A55T	55	Missense	distal	-7	no	8.971	8.917	EPSD	TCGA;ICGC;COSMIC	7.092	Down-regulation
AGC_PKG_PRKG1_ST	P31645	SLC6A4	Q13976	PRKG1	S62	A55V	55	Missense	distal	-7	no	8.971	8.269	EPSD	TCGA;ICGC;COSMIC	7.092	Down-regulation
AGC_PKG_PRKG1_ST	P31645	SLC6A4	Q13976	PRKG1	S149	G146R	146	Missense	distal	-3	no	5.135	9.725	EPSD	TCGA;ICGC;COSMIC	7.092	Gain
AGC_PKG_PRKG1_ST	Q13976	PRKG1	Q13976	PRKG1	S27	E32D	32	Missense	distal	5	no	10.846	10.837	EPSD	TCGA;COSMIC	7.092	Down-regulation
AGC_PKG_PRKG1_ST	Q13976	PRKG1	Q13976	PRKG1	T59	P56T	56	Missense	distal	-3	no	8.128	7.864	EPSD	TCGA;COSMIC	7.092	Down-regulation
AGC_PKG_PRKG1_ST	Q13976	PRKG1	Q13976	PRKG1	S65	Q69H	69	Missense	distal	4	no	8.252	8.311	PhosphoSitePlus	TCGA;ICGC;COSMIC	7.092	Up-regulation
AGC_PKG_PRKG1_ST	Q15052	ARHGEF6	Q13976	PRKG1	S123	E116K	116	Missense	distal	-7	no	9.021	10.023	EPSD	TCGA;ICGC;COSMIC	7.092	Up-regulation
AGC_PKG_PRKG1_ST	Q15052	ARHGEF6	Q13976	PRKG1	S123	N129T	129	Missense	distal	6	no	9.021	8.919	EPSD	TCGA	7.092	Down-regulation
AGC_PKG_PRKG1_ST	Q15052	ARHGEF6	Q13976	PRKG1	S124	S131T	131	Missense	distal	7	no	9.063	9.052	EPSD	TCGA;ICGC;COSMIC	7.092	Down-regulation
AGC_PKG_PRKG1_ST	Q15052	ARHGEF6	Q13976	PRKG1	S124	N129T	129	Missense	distal	5	no	9.063	9.092	EPSD	TCGA	7.092	Up-regulation
AGC_PKG_PRKG1_ST	Q15052	ARHGEF6	Q13976	PRKG1	S150	T156M	156	Missense	distal	6	no	9.345	9.358	EPSD	TCGA;COSMIC	7.092	Up-regulation
AGC_PKG_PRKG1_ST	Q15052	ARHGEF6	Q13976	PRKG1	S150	K151N	151	Missense	proximal	1	no	9.345	9.095	EPSD	TCGA;ICGC;COSMIC	7.092	Down-regulation
AGC_PKG_PRKG1_ST	Q15052	ARHGEF6	Q13976	PRKG1	S150	L146R	146	Missense	distal	-4	no	9.345	10.587	EPSD	TCGA;ICGC	7.092	Up-regulation
AGC_PKG_PRKG1_ST	Q15052	ARHGEF6	Q13976	PRKG1	S225	V229A	229	Missense	distal	4	no	10.936	10.796	EPSD	TCGA;COSMIC	7.092	Down-regulation
AGC_PKG_PRKG1_ST	Q15052	ARHGEF6	Q13976	PRKG1	S225	R222K	222	Missense	distal	-3	no	10.936	8.578	EPSD	TCGA;COSMIC	7.092	Down-regulation
AGC_PKG_PRKG1_ST	Q15052	ARHGEF6	Q13976	PRKG1	S225	L224I	224	Missense	proximal	-1	no	10.936	10.935	EPSD	TCGA;COSMIC	7.092	Down-regulation
AGC_PKG_PRKG1_ST	Q15052	ARHGEF6	Q13976	PRKG1	S488	P485L	485	Missense	distal	-3	no	8.074	5.831	EPSD	TCGA;COSMIC	7.092	Loss
AGC_PKG_PRKG1_ST	Q15052	ARHGEF6	Q13976	PRKG1	S488	G494E	494	Missense	distal	6	no	8.074	8.137	EPSD	TCGA;COSMIC	7.092	Up-regulation
AGC_PKG_PRKG1_ST	Q15052	ARHGEF6	Q13976	PRKG1	S488	R486W	486	Missense	proximal	-2	no	8.074	2.743	EPSD	TCGA;COSMIC	7.092	Loss
AGC_PKG_PRKG1_ST	Q15052	ARHGEF6	Q13976	PRKG1	S561	A566V	566	Missense	distal	5	no	9.873	9.823	EPSD	TCGA;COSMIC	7.092	Down-regulation
AGC_PKG_PRKG1_ST	Q15052	ARHGEF6	Q13976	PRKG1	S561	S568F	568	Missense	distal	7	no	9.873	9.798	EPSD	TCGA;COSMIC	7.092	Down-regulation
AGC_PKG_PRKG1_ST	Q15052	ARHGEF6	Q13976	PRKG1	S561	S563L	563	Missense	proximal	2	no	9.873	9.730	EPSD	TCGA;COSMIC	7.092	Down-regulation
AGC_PKG_PRKG1_ST	Q15052	ARHGEF6	Q13976	PRKG1	S565	S568F	568	Missense	distal	3	no	6.915	7.098	EPSD	TCGA;COSMIC	7.092	Gain
AGC_PKG_PRKG1_ST	Q15052	ARHGEF6	Q13976	PRKG1	S568	G574E	574	Missense	distal	6	no	7.094	7.157	EPSD	TCGA;COSMIC	7.092	Up-regulation
AGC_PKG_PRKG1_ST	Q15052	ARHGEF6	Q13976	PRKG1	S568	A566V	566	Missense	proximal	-2	no	7.094	6.592	EPSD	TCGA;COSMIC	7.092	Loss
AGC_PKG_PRKG1_ST	Q15052	ARHGEF6	Q13976	PRKG1	S568	S568F	568	Missense	central	0	yes	7.094	0.000	EPSD	TCGA;COSMIC	7.092	Loss
AGC_PKG_PRKG1_ST	Q15052	ARHGEF6	Q13976	PRKG1	S568	S563L	563	Missense	distal	-5	no	7.094	7.331	EPSD	TCGA;COSMIC	7.092	Up-regulation
AGC_PKG_PRKG1_ST	Q15052	ARHGEF6	Q13976	PRKG1	T635	K628T	628	Missense	distal	-7	no	9.550	9.171	EPSD	TCGA;COSMIC	7.092	Down-regulation
AGC_PKG_PRKG1_ST	Q15052	ARHGEF6	Q13976	PRKG1	T635	L630I	630	Missense	distal	-5	no	9.550	9.540	EPSD	TCGA;COSMIC;GDSC;CCLE	7.092	Down-regulation
AGC_PKG_PRKG1_ST	Q15052	ARHGEF6	Q13976	PRKG1	S640	E643Q	643	Missense	distal	3	no	12.918	12.734	EPSD	TCGA;COSMIC	7.092	Down-regulation
AGC_PKG_PRKG1_ST	Q15052	ARHGEF6	Q13976	PRKG1	T650	E643Q	643	Missense	distal	-7	no	7.923	8.714	EPSD	TCGA;COSMIC	7.092	Up-regulation
AGC_PKG_PRKG1_ST	Q15052	ARHGEF6	Q13976	PRKG1	T650	A657D	657	Missense	distal	7	no	7.923	7.843	EPSD	TCGA;COSMIC	7.092	Down-regulation
AGC_PKG_PRKG1_ST	Q15052	ARHGEF6	Q13976	PRKG1	S684	Q687H	687	Missense	distal	3	no	11.623	11.707	PhosphoSitePlus	TCGA;COSMIC	7.092	Up-regulation
AGC_PKG_PRKG1_ST	Q15052	ARHGEF6	Q13976	PRKG1	S684	D683Y	683	Missense	proximal	-1	no	11.623	11.693	PhosphoSitePlus	TCGA;COSMIC	7.092	Up-regulation
AGC_PKG_PRKG1_ST	Q15052	ARHGEF6	Q13976	PRKG1	S684	P691H	691	Missense	distal	7	no	11.623	11.680	PhosphoSitePlus	TCGA	7.092	Up-regulation
AGC_PKG_PRKG1_ST	Q15052	ARHGEF6	Q13976	PRKG1	S684	R681Q	681	Missense	distal	-3	no	11.623	7.788	PhosphoSitePlus	TCGA;COSMIC	7.092	Down-regulation
AGC_PKG_PRKG1_ST	Q76M96	CCDC80	Q13976	PRKG1	S134	S134L	134	Missense	central	0	yes	10.300	0.000	EPSD	TCGA;ICGC;COSMIC	7.092	Loss
AGC_PKG_PRKG1_ST	Q76M96	CCDC80	Q13976	PRKG1	S134	R131C	131	Missense	distal	-3	no	10.300	3.278	EPSD	TCGA;ICGC;COSMIC	7.092	Loss
AGC_PKG_PRKG1_ST	Q76M96	CCDC80	Q13976	PRKG1	S134	S136F	136	Missense	proximal	2	no	10.300	10.223	EPSD	TCGA;ICGC;COSMIC	7.092	Down-regulation
AGC_PKG_PRKG1_ST	Q76M96	CCDC80	Q13976	PRKG1	S134	P133S	133	Missense	proximal	-1	no	10.300	10.403	EPSD	TCGA;ICGC;COSMIC;GDSC;CCLE	7.092	Up-regulation
AGC_PKG_PRKG1_ST	Q76M96	CCDC80	Q13976	PRKG1	S134	P133H	133	Missense	proximal	-1	no	10.300	10.356	EPSD	TCGA;ICGC;COSMIC	7.092	Up-regulation
AGC_PKG_PRKG1_ST	Q76M96	CCDC80	Q13976	PRKG1	S305	E309K	309	Missense	distal	4	no	8.249	8.134	EPSD	TCGA;ICGC;COSMIC	7.092	Down-regulation
AGC_PKG_PRKG1_ST	Q76M96	CCDC80	Q13976	PRKG1	S305	G307C	307	Missense	proximal	2	no	8.249	8.239	EPSD	TCGA;ICGC;COSMIC	7.092	Down-regulation
AGC_PKG_PRKG1_ST	Q76M96	CCDC80	Q13976	PRKG1	S305	P304L	304	Missense	proximal	-1	no	8.249	8.152	EPSD	TCGA	7.092	Down-regulation
AGC_PKG_PRKG1_ST	Q76M96	CCDC80	Q13976	PRKG1	S305	S305R	305	Missense	central	0	yes	8.249	0.000	EPSD	TCGA;ICGC;COSMIC	7.092	Loss
AGC_PKG_PRKG1_ST	Q76M96	CCDC80	Q13976	PRKG1	S305	K312I	312	Missense	distal	7	no	8.249	8.106	EPSD	TCGA;ICGC;COSMIC	7.092	Down-regulation
AGC_PKG_PRKG1_ST	Q76M96	CCDC80	Q13976	PRKG1	S308	S305R	305	Missense	distal	-3	no	3.267	8.755	EPSD	TCGA;ICGC;COSMIC	7.092	Gain
AGC_PKG_PRKG1_ST	Q76M96	CCDC80	Q13976	PRKG1	T351	P345S	345	Missense	distal	-6	no	6.880	7.196	EPSD	TCGA;ICGC;COSMIC	7.092	Gain
AGC_PKG_PRKG1_ST	Q76M96	CCDC80	Q13976	PRKG1	T352	P345S	345	Missense	distal	-7	no	7.459	8.226	EPSD	TCGA;ICGC;COSMIC	7.092	Up-regulation
AGC_PKG_PRKG1_ST	Q76M96	CCDC80	Q13976	PRKG1	S366	R363Q	363	Missense	distal	-3	no	10.079	6.244	EPSD	TCGA;ICGC	7.092	Loss
AGC_PKG_PRKG1_ST	Q76M96	CCDC80	Q13976	PRKG1	T370	R363Q	363	Missense	distal	-7	no	9.765	9.089	EPSD	TCGA;ICGC	7.092	Down-regulation
AGC_PKG_PRKG1_ST	Q76M96	CCDC80	Q13976	PRKG1	S409	R406M	406	Missense	distal	-3	no	12.972	7.668	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	7.092	Down-regulation
AGC_PKG_PRKG1_ST	Q76M96	CCDC80	Q13976	PRKG1	S409	E412K	412	Missense	distal	3	no	12.972	12.798	EPSD;PhosphoSitePlus	TCGA;ICGC	7.092	Down-regulation
AGC_PKG_PRKG1_ST	Q76M96	CCDC80	Q13976	PRKG1	S409	E412D	412	Missense	distal	3	no	12.972	12.987	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	7.092	Up-regulation
AGC_PKG_PRKG1_ST	Q76M96	CCDC80	Q13976	PRKG1	S409	L414I	414	Missense	distal	5	no	12.972	12.988	EPSD;PhosphoSitePlus	TCGA;ICGC	7.092	Up-regulation
AGC_PKG_PRKG1_ST	Q76M96	CCDC80	Q13976	PRKG1	S434	T430A	430	Missense	distal	-4	no	13.432	13.546	PhosphoSitePlus;EPSD	TCGA;ICGC;COSMIC	7.092	Up-regulation
AGC_PKG_PRKG1_ST	Q76M96	CCDC80	Q13976	PRKG1	S434	E440Q	440	Missense	distal	6	no	13.432	13.224	PhosphoSitePlus;EPSD	TCGA;ICGC;COSMIC	7.092	Down-regulation
AGC_PKG_PRKG1_ST	Q76M96	CCDC80	Q13976	PRKG1	S503	Q498L	498	Missense	distal	-5	no	7.151	7.407	EPSD	TCGA;ICGC;COSMIC	7.092	Up-regulation
AGC_PKG_PRKG1_ST	Q76M96	CCDC80	Q13976	PRKG1	S503	L502V	502	Missense	proximal	-1	no	7.151	7.238	EPSD	TCGA;ICGC;COSMIC	7.092	Up-regulation
AGC_PKG_PRKG1_ST	Q76M96	CCDC80	Q13976	PRKG1	S572	S565C	565	Missense	distal	-7	no	7.760	6.964	EPSD	TCGA;ICGC;COSMIC	7.092	Loss
AGC_PKG_PRKG1_ST	Q76M96	CCDC80	Q13976	PRKG1	S572	E579D	579	Missense	distal	7	no	7.760	7.746	EPSD	TCGA;ICGC;COSMIC	7.092	Down-regulation
AGC_PKG_PRKG1_ST	Q76M96	CCDC80	Q13976	PRKG1	S611	G617W	617	Missense	distal	6	no	7.178	7.304	EPSD	TCGA;ICGC;COSMIC	7.092	Up-regulation
AGC_PKG_PRKG1_ST	O76074	PDE5A	Q13976	PRKG1	T76	E77K	77	Missense	proximal	1	no	7.066	7.373	EPSD	TCGA;ICGC;COSMIC	7.092	Gain
AGC_PKG_PRKG1_ST	O76074	PDE5A	Q13976	PRKG1	S80	E77K	77	Missense	distal	-3	no	4.367	8.950	EPSD	TCGA;ICGC;COSMIC	7.092	Gain
AGC_PKG_PRKG1_ST	O76074	PDE5A	Q13976	PRKG1	S102	R108W	108	Missense	distal	6	no	11.786	12.127	PhosphoSitePlus	TCGA	7.092	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P19634	SLC9A1	P28482	MAPK1	S11	R14W	14	Missense	distal	3	no	13.032	13.182	EPSD	TCGA;COSMIC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P19634	SLC9A1	P28482	MAPK1	S11	F16I	16	Missense	distal	5	no	13.032	12.912	EPSD	TCGA;ICGC;COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P19634	SLC9A1	P28482	MAPK1	T68	T62I	62	Missense	distal	-6	no	13.700	13.622	EPSD	TCGA;ICGC;COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P19634	SLC9A1	P28482	MAPK1	T68	N75H	75	Missense	distal	7	no	13.700	13.940	EPSD	TCGA;ICGC;COSMIC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P19634	SLC9A1	P28482	MAPK1	S599	A600V	600	Missense	proximal	1	no	8.293	6.383	EPSD	TCGA;ICGC	8.102	Loss
CMGC_MAPK_ERK1_MAPK1_ST	P19634	SLC9A1	P28482	MAPK1	S693	R698P	698	Missense	distal	5	no	14.394	14.344	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P19634	SLC9A1	P28482	MAPK1	S697	R698P	698	Missense	proximal	1	no	5.328	14.982	EPSD	TCGA;ICGC;COSMIC	8.102	Gain
CMGC_MAPK_ERK1_MAPK1_ST	P19634	SLC9A1	P28482	MAPK1	S726	D731N	731	Missense	distal	5	no	16.735	16.637	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P19634	SLC9A1	P28482	MAPK1	S770	S770L	770	Missense	central	0	yes	8.372	0.000	EPSD;PhosphoSitePlus	TCGA;COSMIC	8.102	Loss
CMGC_MAPK_ERK1_MAPK1_ST	P19634	SLC9A1	P28482	MAPK1	S770	R765W	765	Missense	distal	-5	no	8.372	8.648	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC;GDSC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P19634	SLC9A1	P28482	MAPK1	S771	S770L	770	Missense	proximal	-1	no	15.111	15.094	EPSD;PhosphoSitePlus	TCGA;COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P19634	SLC9A1	P28482	MAPK1	S771	R765W	765	Missense	distal	-6	no	15.111	14.890	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC;GDSC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P19634	SLC9A1	P28482	MAPK1	T779	A781V	781	Missense	proximal	2	no	15.577	15.653	PhosphoSitePlus;EPSD	TCGA;COSMIC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P19634	SLC9A1	P28482	MAPK1	T779	A781T	781	Missense	proximal	2	no	15.577	15.656	PhosphoSitePlus;EPSD	TCGA;COSMIC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P19634	SLC9A1	P28482	MAPK1	S785	A781V	781	Missense	distal	-4	no	13.035	12.974	EPSD;PhosphoSitePlus	TCGA;COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P19634	SLC9A1	P28482	MAPK1	S785	A781T	781	Missense	distal	-4	no	13.035	13.015	EPSD;PhosphoSitePlus	TCGA;COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P19634	SLC9A1	P28482	MAPK1	S785	S787I	787	Missense	proximal	2	no	13.035	12.892	EPSD;PhosphoSitePlus	TCGA;COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P19634	SLC9A1	P28482	MAPK1	S788	A781V	781	Missense	distal	-7	no	8.359	8.343	EPSD	TCGA;COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P19634	SLC9A1	P28482	MAPK1	S788	A781T	781	Missense	distal	-7	no	8.359	8.344	EPSD	TCGA;COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P19634	SLC9A1	P28482	MAPK1	S788	S787I	787	Missense	proximal	-1	no	8.359	8.336	EPSD	TCGA;COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P11388	TOP2A	P28482	MAPK1	S4	E2K	2	Missense	proximal	-2	no	13.568	13.528	EPSD	TCGA	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P11388	TOP2A	P28482	MAPK1	S4	P5L	5	Missense	proximal	1	no	13.568	4.758	EPSD	TCGA;ICGC;COSMIC	8.102	Loss
CMGC_MAPK_ERK1_MAPK1_ST	P11388	TOP2A	P28482	MAPK1	S387	S387R	387	Missense	central	0	yes	10.266	0.000	EPSD	TCGA	8.102	Loss
CMGC_MAPK_ERK1_MAPK1_ST	P11388	TOP2A	P28482	MAPK1	T694	D697Y	697	Missense	distal	3	no	9.064	9.105	EPSD	TCGA;ICGC;COSMIC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P11388	TOP2A	P28482	MAPK1	T694	T689N	689	Missense	distal	-5	no	9.064	8.987	EPSD	TCGA;ICGC;COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P11388	TOP2A	P28482	MAPK1	T950	N945I	945	Missense	distal	-5	no	14.257	14.441	EPSD	TCGA	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P11388	TOP2A	P28482	MAPK1	T950	T955A	955	Missense	distal	5	no	14.257	14.171	EPSD	TCGA;ICGC;COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P11388	TOP2A	P28482	MAPK1	T950	E948G	948	Missense	proximal	-2	no	14.257	13.443	EPSD	TCGA;ICGC;COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P11388	TOP2A	P28482	MAPK1	T950	E948D	948	Missense	proximal	-2	no	14.257	13.335	EPSD	TCGA;ICGC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P11388	TOP2A	P28482	MAPK1	S1115	S1117C	1117	Missense	proximal	2	no	8.958	8.726	EPSD	TCGA;ICGC;COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P11388	TOP2A	P28482	MAPK1	S1115	D1116N	1116	Missense	proximal	1	no	8.958	-2.069	EPSD	TCGA;ICGC;COSMIC	8.102	Loss
CMGC_MAPK_ERK1_MAPK1_ST	P11388	TOP2A	P28482	MAPK1	S1115	S1117F	1117	Missense	proximal	2	no	8.958	8.826	EPSD	TCGA;ICGC;COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P11388	TOP2A	P28482	MAPK1	S1115	D1120Y	1120	Missense	distal	5	no	8.958	8.644	EPSD	TCGA;ICGC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P11388	TOP2A	P28482	MAPK1	S1213	R1215H	1215	Missense	proximal	2	no	13.923	13.680	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P11388	TOP2A	P28482	MAPK1	S1213	E1209D	1209	Missense	distal	-4	no	13.923	13.938	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P11388	TOP2A	P28482	MAPK1	S1247	E1245K	1245	Missense	proximal	-2	no	14.736	14.696	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P11388	TOP2A	P28482	MAPK1	S1247	E1242G	1242	Missense	distal	-5	no	14.736	14.779	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P11388	TOP2A	P28482	MAPK1	S1247	E1242D	1242	Missense	distal	-5	no	14.736	14.781	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P11388	TOP2A	P28482	MAPK1	S1354	P1350L	1350	Missense	distal	-4	no	14.705	14.401	EPSD;PhosphoSitePlus	TCGA	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P11388	TOP2A	P28482	MAPK1	S1361	E1368Q	1368	Missense	distal	7	no	15.536	15.714	PhosphoSitePlus;EPSD	TCGA;ICGC;COSMIC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	O00562	PITPNM1	P28482	MAPK1	S300	P301L	301	Missense	proximal	1	no	13.181	4.371	EPSD	TCGA;ICGC;COSMIC	8.102	Loss
CMGC_MAPK_ERK1_MAPK1_ST	O00562	PITPNM1	P28482	MAPK1	S300	G296C	296	Missense	distal	-4	no	13.181	12.803	EPSD	TCGA;ICGC;COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	O00562	PITPNM1	P28482	MAPK1	S326	Q328K	328	Missense	proximal	2	no	13.334	13.444	EPSD	TCGA;ICGC;COSMIC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	O00562	PITPNM1	P28482	MAPK1	S326	G322R	322	Missense	distal	-4	no	13.334	13.594	EPSD	TCGA;ICGC;COSMIC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	O00562	PITPNM1	P28482	MAPK1	S382	T389A	389	Missense	distal	7	no	14.761	14.790	EPSD	TCGA;ICGC;COSMIC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	O00562	PITPNM1	P28482	MAPK1	S382	F376L	376	Missense	distal	-6	no	14.761	14.779	EPSD	TCGA;ICGC;COSMIC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	O00562	PITPNM1	P28482	MAPK1	T389	P392S	392	Missense	distal	3	no	13.607	13.676	EPSD	TCGA;ICGC;COSMIC;GDSC;CCLE	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	O00562	PITPNM1	P28482	MAPK1	T389	T389A	389	Missense	central	0	yes	13.607	0.000	EPSD	TCGA;ICGC;COSMIC	8.102	Loss
CMGC_MAPK_ERK1_MAPK1_ST	O00562	PITPNM1	P28482	MAPK1	T389	P392H	392	Missense	distal	3	no	13.607	13.695	EPSD	TCGA;ICGC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	O00562	PITPNM1	P28482	MAPK1	S600	E597K	597	Missense	distal	-3	no	16.362	16.284	EPSD	TCGA;ICGC;COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	O00562	PITPNM1	P28482	MAPK1	S621	L617R	617	Missense	distal	-4	no	14.648	14.863	EPSD	TCGA;ICGC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	O00562	PITPNM1	P28482	MAPK1	S638	Q645E	645	Missense	distal	7	no	14.568	14.390	EPSD	TCGA;ICGC;COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	O00562	PITPNM1	P28482	MAPK1	S638	S634N	634	Missense	distal	-4	no	14.568	14.609	EPSD	TCGA;ICGC;COSMIC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	O00562	PITPNM1	P28482	MAPK1	S638	R631H	631	Missense	distal	-7	no	14.568	14.557	EPSD	TCGA;ICGC;COSMIC;GDSC;CCLE	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	O00562	PITPNM1	P28482	MAPK1	S638	E642K	642	Missense	distal	4	no	14.568	14.582	EPSD	TCGA;ICGC;COSMIC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	O00562	PITPNM1	P28482	MAPK1	T755	V756L	756	Missense	proximal	1	no	7.882	8.613	EPSD	TCGA;COSMIC	8.102	Gain
CMGC_MAPK_ERK1_MAPK1_ST	O00562	PITPNM1	P28482	MAPK1	S896	K903R	903	Missense	distal	7	no	14.180	14.235	EPSD	TCGA	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	O00562	PITPNM1	P28482	MAPK1	S896	E890D	890	Missense	distal	-6	no	14.180	14.193	EPSD	TCGA;COSMIC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	O00562	PITPNM1	P28482	MAPK1	S896	P897L	897	Missense	proximal	1	no	14.180	5.371	EPSD	TCGA;COSMIC	8.102	Loss
CMGC_MAPK_ERK1_MAPK1_ST	O00562	PITPNM1	P28482	MAPK1	S1191	V1198M	1198	Missense	distal	7	no	8.027	8.104	EPSD	TCGA;COSMIC	8.102	Gain
CMGC_MAPK_ERK1_MAPK1_ST	O00562	PITPNM1	P28482	MAPK1	T1223	A1216V	1216	Missense	distal	-7	no	17.459	17.443	EPSD;PhosphoSitePlus	TCGA;COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	O00562	PITPNM1	P28482	MAPK1	T1223	R1230W	1230	Missense	distal	7	no	17.459	18.431	EPSD;PhosphoSitePlus	TCGA;COSMIC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	O00562	PITPNM1	P28482	MAPK1	T1223	P1221A	1221	Missense	proximal	-2	no	17.459	14.313	EPSD;PhosphoSitePlus	TCGA;COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	O00562	PITPNM1	P28482	MAPK1	T1223	E1219K	1219	Missense	distal	-4	no	17.459	17.477	EPSD;PhosphoSitePlus	TCGA;COSMIC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	O00562	PITPNM1	P28482	MAPK1	T1223	R1218C	1218	Missense	distal	-5	no	17.459	17.689	EPSD;PhosphoSitePlus	TCGA;COSMIC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	O00562	PITPNM1	P28482	MAPK1	T1227	R1230W	1230	Missense	distal	3	no	10.469	10.619	EPSD	TCGA;COSMIC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	O00562	PITPNM1	P28482	MAPK1	T1227	P1221A	1221	Missense	distal	-6	no	10.469	10.430	EPSD	TCGA;COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	O00562	PITPNM1	P28482	MAPK1	T1227	R1234W	1234	Missense	distal	7	no	10.469	11.441	EPSD	TCGA;COSMIC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	O00562	PITPNM1	P28482	MAPK1	T1227	R1234L	1234	Missense	distal	7	no	10.469	10.754	EPSD	TCGA;COSMIC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P15056	BRAF	P28482	MAPK1	S76	Y82N	82	Missense	distal	6	no	8.648	9.171	EPSD	TCGA;ICGC;COSMIC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P15056	BRAF	P28482	MAPK1	S76	E80D	80	Missense	distal	4	no	8.648	8.578	EPSD	TCGA;ICGC;COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P15056	BRAF	P28482	MAPK1	S76	E80G	80	Missense	distal	4	no	8.648	8.626	EPSD	TCGA;ICGC;COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P15056	BRAF	P28482	MAPK1	S151	R146W	146	Missense	distal	-5	no	15.658	15.934	EPSD	TCGA;ICGC;COSMIC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P15056	BRAF	P28482	MAPK1	T244	L245F	245	Missense	proximal	1	no	6.729	8.969	EPSD	TCGA;ICGC;COSMIC	8.102	Gain
CMGC_MAPK_ERK1_MAPK1_ST	P15056	BRAF	P28482	MAPK1	S317	L312I	312	Missense	distal	-5	no	13.415	13.475	EPSD	TCGA;ICGC;COSMIC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P15056	BRAF	P28482	MAPK1	S317	A320T	320	Missense	distal	3	no	13.415	13.398	EPSD	TCGA;ICGC;COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P15056	BRAF	P28482	MAPK1	S317	P318L	318	Missense	proximal	1	no	13.415	4.605	EPSD	TCGA;ICGC;COSMIC	8.102	Loss
CMGC_MAPK_ERK1_MAPK1_ST	P15056	BRAF	P28482	MAPK1	S317	P318S	318	Missense	proximal	1	no	13.415	4.020	EPSD	TCGA;ICGC;COSMIC	8.102	Loss
CMGC_MAPK_ERK1_MAPK1_ST	P15056	BRAF	P28482	MAPK1	S317	S317F	317	Missense	central	0	yes	13.415	0.000	EPSD	TCGA;ICGC;COSMIC	8.102	Loss
CMGC_MAPK_ERK1_MAPK1_ST	P15056	BRAF	P28482	MAPK1	S319	L312I	312	Missense	distal	-7	no	8.527	8.507	EPSD	TCGA;ICGC;COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P15056	BRAF	P28482	MAPK1	S319	A320T	320	Missense	proximal	1	no	8.527	7.658	EPSD	TCGA;ICGC;COSMIC	8.102	Loss
CMGC_MAPK_ERK1_MAPK1_ST	P15056	BRAF	P28482	MAPK1	S319	P318L	318	Missense	proximal	-1	no	8.527	8.467	EPSD	TCGA;ICGC;COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P15056	BRAF	P28482	MAPK1	S319	P318S	318	Missense	proximal	-1	no	8.527	8.483	EPSD	TCGA;ICGC;COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P15056	BRAF	P28482	MAPK1	S319	S317F	317	Missense	proximal	-2	no	8.527	8.720	EPSD	TCGA;ICGC;COSMIC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P15056	BRAF	P28482	MAPK1	S323	A320T	320	Missense	distal	-3	no	9.556	9.714	EPSD	TCGA;ICGC;COSMIC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P15056	BRAF	P28482	MAPK1	S323	P318L	318	Missense	distal	-5	no	9.556	9.705	EPSD	TCGA;ICGC;COSMIC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P15056	BRAF	P28482	MAPK1	S323	P318S	318	Missense	distal	-5	no	9.556	9.631	EPSD	TCGA;ICGC;COSMIC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P15056	BRAF	P28482	MAPK1	S323	S317F	317	Missense	distal	-6	no	9.556	9.472	EPSD	TCGA;ICGC;COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P15056	BRAF	P28482	MAPK1	S335	P341L	341	Missense	distal	6	no	14.911	14.504	EPSD	TCGA;ICGC;COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P15056	BRAF	P28482	MAPK1	T401	T401I	401	Missense	central	0	yes	14.262	0.000	PhosphoSitePlus;EPSD	TCGA;ICGC;COSMIC	8.102	Loss
CMGC_MAPK_ERK1_MAPK1_ST	P15056	BRAF	P28482	MAPK1	T401	G397S	397	Missense	distal	-4	no	14.262	14.528	PhosphoSitePlus;EPSD	TCGA;ICGC;COSMIC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P15056	BRAF	P28482	MAPK1	T401	T401A	401	Missense	central	0	yes	14.262	0.000	PhosphoSitePlus;EPSD	TCGA;ICGC;COSMIC	8.102	Loss
CMGC_MAPK_ERK1_MAPK1_ST	P15056	BRAF	P28482	MAPK1	S419	S419Y	419	Missense	central	0	yes	14.619	0.000	EPSD	TCGA;ICGC;COSMIC	8.102	Loss
CMGC_MAPK_ERK1_MAPK1_ST	P15056	BRAF	P28482	MAPK1	S465	G466E	466	Missense	proximal	1	no	7.168	8.462	EPSD	TCGA;ICGC;COSMIC	8.102	Gain
CMGC_MAPK_ERK1_MAPK1_ST	P15056	BRAF	P28482	MAPK1	S465	G466A	466	Missense	proximal	1	no	7.168	9.603	EPSD	TCGA;ICGC;COSMIC	8.102	Gain
CMGC_MAPK_ERK1_MAPK1_ST	P15056	BRAF	P28482	MAPK1	S675	L678I	678	Missense	distal	3	no	15.348	15.386	EPSD	TCGA;ICGC;COSMIC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P15056	BRAF	P28482	MAPK1	S732	L733F	733	Missense	proximal	1	no	7.227	9.467	EPSD	TCGA;ICGC;COSMIC	8.102	Gain
CMGC_MAPK_ERK1_MAPK1_ST	P15056	BRAF	P28482	MAPK1	S750	P751A	751	Missense	proximal	1	no	14.197	6.567	EPSD	TCGA;ICGC;COSMIC	8.102	Loss
CMGC_MAPK_ERK1_MAPK1_ST	P15056	BRAF	P28482	MAPK1	S750	A747D	747	Missense	distal	-3	no	14.197	14.436	EPSD	TCGA;ICGC;COSMIC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P15056	BRAF	P28482	MAPK1	T753	P751A	751	Missense	proximal	-2	no	19.816	16.669	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P15056	BRAF	P28482	MAPK1	T753	A747D	747	Missense	distal	-6	no	19.816	19.878	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P04626	ERBB2	P28482	MAPK1	S196	S196F	196	Missense	central	0	yes	17.483	0.000	EPSD	TCGA;COSMIC	8.102	Loss
CMGC_MAPK_ERK1_MAPK1_ST	P04626	ERBB2	P28482	MAPK1	S196	R203C	203	Missense	distal	7	no	17.483	18.139	EPSD	TCGA;COSMIC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P04626	ERBB2	P28482	MAPK1	T701	V697L	697	Missense	distal	-4	no	17.817	17.867	PhosphoSitePlus	TCGA;COSMIC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P04626	ERBB2	P28482	MAPK1	S760	L755S	755	Missense	distal	-5	no	14.838	14.763	EPSD	TCGA;COSMIC;GDSC;CCLE	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P04626	ERBB2	P28482	MAPK1	S760	I767M	767	Missense	distal	7	no	14.838	14.649	EPSD	TCGA;COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P04626	ERBB2	P28482	MAPK1	S760	L755M	755	Missense	distal	-5	no	14.838	14.841	EPSD	TCGA;COSMIC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P04626	ERBB2	P28482	MAPK1	S760	L755W	755	Missense	distal	-5	no	14.838	15.012	EPSD	TCGA;COSMIC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P04626	ERBB2	P28482	MAPK1	S760	R756K	756	Missense	distal	-4	no	14.838	14.916	EPSD	TCGA;COSMIC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P04626	ERBB2	P28482	MAPK1	S760	I767F	767	Missense	distal	7	no	14.838	14.637	EPSD	TCGA;COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P04626	ERBB2	P28482	MAPK1	S779	V777L	777	Missense	proximal	-2	no	13.904	13.859	EPSD	TCGA;COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P04626	ERBB2	P28482	MAPK1	S779	G776S	776	Missense	distal	-3	no	13.904	13.916	EPSD	TCGA;COSMIC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P04626	ERBB2	P28482	MAPK1	S779	V777M	777	Missense	proximal	-2	no	13.904	11.762	EPSD	TCGA;COSMIC;GDSC;CCLE	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P04626	ERBB2	P28482	MAPK1	S779	R784C	784	Missense	distal	5	no	13.904	13.472	EPSD	TCGA;COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P04626	ERBB2	P28482	MAPK1	S779	G776V	776	Missense	distal	-3	no	13.904	13.785	EPSD	TCGA;COSMIC;GDSC;CCLE	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P04626	ERBB2	P28482	MAPK1	S998	L994V	994	Missense	distal	-4	no	17.256	17.206	EPSD	TCGA	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P04626	ERBB2	P28482	MAPK1	S998	D993N	993	Missense	distal	-5	no	17.256	17.211	EPSD	TCGA;COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P04626	ERBB2	P28482	MAPK1	S1073	E1079K	1079	Missense	distal	6	no	16.192	16.215	EPSD	TCGA;COSMIC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P04626	ERBB2	P28482	MAPK1	S1073	A1070V	1070	Missense	distal	-3	no	16.192	16.252	EPSD	TCGA;COSMIC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P04626	ERBB2	P28482	MAPK1	S1073	G1080W	1080	Missense	distal	7	no	16.192	17.099	EPSD	TCGA;COSMIC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P04626	ERBB2	P28482	MAPK1	S1107	R1111W	1111	Missense	distal	4	no	11.604	11.320	EPSD	TCGA;COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P04626	ERBB2	P28482	MAPK1	S1134	V1128I	1128	Missense	distal	-6	no	15.624	15.583	EPSD	TCGA;COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P04626	ERBB2	P28482	MAPK1	S1151	R1146Q	1146	Missense	distal	-5	no	16.299	16.377	EPSD	TCGA;COSMIC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P04626	ERBB2	P28482	MAPK1	T1198	P1199T	1199	Missense	proximal	1	no	15.433	6.934	EPSD	TCGA;COSMIC	8.102	Loss
CMGC_MAPK_ERK1_MAPK1_ST	P04626	ERBB2	P28482	MAPK1	S1214	H1208Y	1208	Missense	distal	-6	no	13.860	13.794	EPSD	TCGA;COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P04626	ERBB2	P28482	MAPK1	S1214	N1219S	1219	Missense	distal	5	no	13.860	13.932	EPSD	TCGA;COSMIC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P04626	ERBB2	P28482	MAPK1	S1214	S1214N	1214	Missense	central	0	yes	13.860	0.000	EPSD	TCGA;COSMIC;CCLE	8.102	Loss
CMGC_MAPK_ERK1_MAPK1_ST	P04626	ERBB2	P28482	MAPK1	S1235	P1234S	1234	Missense	proximal	-1	no	8.966	8.923	EPSD	TCGA;COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P04626	ERBB2	P28482	MAPK1	S1235	P1233S	1233	Missense	proximal	-2	no	8.966	6.132	EPSD	TCGA;COSMIC	8.102	Loss
CMGC_MAPK_ERK1_MAPK1_ST	P04626	ERBB2	P28482	MAPK1	S1235	P1241H	1241	Missense	distal	6	no	8.966	8.661	EPSD	TCGA;COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P04626	ERBB2	P28482	MAPK1	T1236	P1234S	1234	Missense	proximal	-2	no	10.749	7.915	EPSD	TCGA;COSMIC	8.102	Loss
CMGC_MAPK_ERK1_MAPK1_ST	P04626	ERBB2	P28482	MAPK1	T1236	P1233S	1233	Missense	distal	-3	no	10.749	10.573	EPSD	TCGA;COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P04626	ERBB2	P28482	MAPK1	T1236	P1241H	1241	Missense	distal	5	no	10.749	10.622	EPSD	TCGA;COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P04626	ERBB2	P28482	MAPK1	T1240	E1244Q	1244	Missense	distal	4	no	16.539	16.468	EPSD	TCGA;COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P04626	ERBB2	P28482	MAPK1	T1240	E1247A	1247	Missense	distal	7	no	16.539	16.779	EPSD	TCGA;COSMIC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P04626	ERBB2	P28482	MAPK1	T1240	P1234S	1234	Missense	distal	-6	no	16.539	16.513	EPSD	TCGA;COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P04626	ERBB2	P28482	MAPK1	T1240	P1233S	1233	Missense	distal	-7	no	16.539	16.535	EPSD	TCGA;COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P04626	ERBB2	P28482	MAPK1	T1240	P1241H	1241	Missense	proximal	1	no	16.539	8.715	EPSD	TCGA;COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P04626	ERBB2	P28482	MAPK1	T1242	E1244Q	1244	Missense	proximal	2	no	9.550	9.440	EPSD	TCGA;COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P04626	ERBB2	P28482	MAPK1	T1242	E1247A	1247	Missense	distal	5	no	9.550	9.435	EPSD	TCGA;COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P04626	ERBB2	P28482	MAPK1	T1242	P1241H	1241	Missense	proximal	-1	no	9.550	9.508	EPSD	TCGA;COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P36956	SREBF1	P28482	MAPK1	T105	P106A	106	Missense	proximal	1	no	13.491	5.861	EPSD	TCGA;COSMIC	8.102	Loss
CMGC_MAPK_ERK1_MAPK1_ST	P36956	SREBF1	P28482	MAPK1	T105	S98P	98	Missense	distal	-7	no	13.491	13.496	EPSD	TCGA;COSMIC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P36956	SREBF1	P28482	MAPK1	S117	F116S	116	Missense	proximal	-1	no	13.022	13.068	EPSD;PhosphoSitePlus	TCGA;COSMIC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P36956	SREBF1	P28482	MAPK1	T426	T419I	419	Missense	distal	-7	no	11.508	11.493	EPSD	TCGA;COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P36956	SREBF1	P28482	MAPK1	T426	V421A	421	Missense	distal	-5	no	11.508	11.537	EPSD	TCGA	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P36956	SREBF1	P28482	MAPK1	S461	P459L	459	Missense	proximal	-2	no	18.829	16.912	EPSD	TCGA	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P10636	MAPT	P28482	MAPK1	S46	T52I	52	Missense	distal	6	no	14.520	14.063	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P10636	MAPT	P28482	MAPK1	S46	P47S	47	Missense	proximal	1	no	14.520	5.125	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	8.102	Loss
CMGC_MAPK_ERK1_MAPK1_ST	P10636	MAPT	P28482	MAPK1	S46	P47L	47	Missense	proximal	1	no	14.520	5.710	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	8.102	Loss
CMGC_MAPK_ERK1_MAPK1_ST	P10636	MAPT	P28482	MAPK1	S46	G42C	42	Missense	distal	-4	no	14.520	14.142	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P10636	MAPT	P28482	MAPK1	T50	D54E	54	Missense	distal	4	no	16.282	16.352	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P10636	MAPT	P28482	MAPK1	T50	T52I	52	Missense	proximal	2	no	16.282	16.161	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P10636	MAPT	P28482	MAPK1	T50	P47S	47	Missense	distal	-3	no	16.282	16.105	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P10636	MAPT	P28482	MAPK1	T50	P47L	47	Missense	distal	-3	no	16.282	15.898	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P10636	MAPT	P28482	MAPK1	T50	G55R	55	Missense	distal	5	no	16.282	16.333	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P10636	MAPT	P28482	MAPK1	T69	A72V	72	Missense	distal	3	no	14.584	14.563	EPSD	TCGA;ICGC;COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P10636	MAPT	P28482	MAPK1	T69	A66S	66	Missense	distal	-3	no	14.584	14.775	EPSD	TCGA;ICGC;COSMIC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P10636	MAPT	P28482	MAPK1	T111	E117K	117	Missense	distal	6	no	12.736	12.759	EPSD	TCGA;ICGC;COSMIC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P10636	MAPT	P28482	MAPK1	T111	A118V	118	Missense	distal	7	no	12.736	12.838	EPSD	TCGA;ICGC;COSMIC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P10636	MAPT	P28482	MAPK1	S228	S232Y	232	Missense	distal	4	no	14.224	14.030	EPSD	TCGA;ICGC;COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P10636	MAPT	P28482	MAPK1	S228	D223Y	223	Missense	distal	-5	no	14.224	14.359	EPSD	TCGA;ICGC;COSMIC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P10636	MAPT	P28482	MAPK1	S228	S227F	227	Missense	proximal	-1	no	14.224	14.178	EPSD	TCGA;ICGC;COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P10636	MAPT	P28482	MAPK1	S228	P234L	234	Missense	distal	6	no	14.224	13.817	EPSD	TCGA;ICGC;COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P10636	MAPT	P28482	MAPK1	S232	S232Y	232	Missense	central	0	yes	15.028	0.000	EPSD	TCGA;ICGC;COSMIC	8.102	Loss
CMGC_MAPK_ERK1_MAPK1_ST	P10636	MAPT	P28482	MAPK1	S232	S227F	227	Missense	distal	-5	no	15.028	15.116	EPSD	TCGA;ICGC;COSMIC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P10636	MAPT	P28482	MAPK1	S232	P234L	234	Missense	proximal	2	no	15.028	14.880	EPSD	TCGA;ICGC;COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P10636	MAPT	P28482	MAPK1	S238	S232Y	232	Missense	distal	-6	no	15.270	15.156	EPSD	TCGA;ICGC;COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P10636	MAPT	P28482	MAPK1	S238	A240T	240	Missense	proximal	2	no	15.270	15.349	EPSD	TCGA;ICGC;COSMIC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P10636	MAPT	P28482	MAPK1	S238	P234L	234	Missense	distal	-4	no	15.270	14.966	EPSD	TCGA;ICGC;COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P10636	MAPT	P28482	MAPK1	S238	R244Q	244	Missense	distal	6	no	15.270	15.090	EPSD	TCGA;ICGC;COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P10636	MAPT	P28482	MAPK1	T248	R244Q	244	Missense	distal	-4	no	9.386	9.283	EPSD	TCGA;ICGC;COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P10636	MAPT	P28482	MAPK1	S411	P415L	415	Missense	distal	4	no	14.042	13.921	EPSD	TCGA;ICGC;COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P10636	MAPT	P28482	MAPK1	T416	P415L	415	Missense	proximal	-1	no	13.113	13.053	EPSD	TCGA;ICGC;COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P10636	MAPT	P28482	MAPK1	S428	A430S	430	Missense	proximal	2	no	15.089	15.190	EPSD	TCGA;ICGC;COSMIC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P10636	MAPT	P28482	MAPK1	S428	V431L	431	Missense	distal	3	no	15.089	15.121	EPSD	TCGA;ICGC;COSMIC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P10636	MAPT	P28482	MAPK1	S428	A430V	430	Missense	proximal	2	no	15.089	15.165	EPSD	TCGA;ICGC;COSMIC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P10636	MAPT	P28482	MAPK1	S437	S444F	444	Missense	distal	7	no	7.881	8.228	EPSD	TCGA;ICGC	8.102	Gain
CMGC_MAPK_ERK1_MAPK1_ST	P10636	MAPT	P28482	MAPK1	S438	P436T	436	Missense	proximal	-2	no	19.115	16.416	EPSD	TCGA;ICGC;COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P10636	MAPT	P28482	MAPK1	S438	P436L	436	Missense	proximal	-2	no	19.115	17.198	EPSD	TCGA;ICGC;COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P10636	MAPT	P28482	MAPK1	S438	S443F	443	Missense	distal	5	no	19.115	18.918	EPSD	TCGA;ICGC;COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P10636	MAPT	P28482	MAPK1	S438	V431L	431	Missense	distal	-7	no	19.115	19.122	EPSD	TCGA;ICGC;COSMIC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P10636	MAPT	P28482	MAPK1	S438	S444F	444	Missense	distal	6	no	19.115	18.674	EPSD	TCGA;ICGC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P10636	MAPT	P28482	MAPK1	T470	R472Q	472	Missense	proximal	2	no	14.781	14.490	EPSD	TCGA	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P10636	MAPT	P28482	MAPK1	T470	R472W	472	Missense	proximal	2	no	14.781	14.413	EPSD	TCGA;COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P10636	MAPT	P28482	MAPK1	T492	A485T	485	Missense	distal	-7	no	11.959	11.944	EPSD	TCGA;COSMIC;GDSC;CCLE	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P10636	MAPT	P28482	MAPK1	T492	P493Q	493	Missense	proximal	1	no	11.959	3.465	EPSD	TCGA;COSMIC	8.102	Loss
CMGC_MAPK_ERK1_MAPK1_ST	P10636	MAPT	P28482	MAPK1	T498	P493Q	493	Missense	distal	-5	no	17.714	17.839	EPSD	TCGA;COSMIC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q13541	EIF4EBP1	P28482	MAPK1	T70	L75M	75	Missense	distal	5	no	14.934	14.961	EPSD;PhosphoSitePlus	TCGA;ICGC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q13541	EIF4EBP1	P28482	MAPK1	S83	S86N	86	Missense	distal	3	no	16.492	16.414	EPSD	TCGA;ICGC;COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q13541	EIF4EBP1	P28482	MAPK1	S86	S86N	86	Missense	central	0	yes	8.587	0.000	EPSD	TCGA;ICGC;COSMIC	8.102	Loss
CMGC_MAPK_ERK1_MAPK1_ST	Q13541	EIF4EBP1	P28482	MAPK1	S101	A107V	107	Missense	distal	6	no	15.740	15.821	EPSD	TCGA;ICGC;COSMIC;GDSC;CCLE	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q13541	EIF4EBP1	P28482	MAPK1	S112	G109S	109	Missense	distal	-3	no	8.221	8.234	EPSD	TCGA	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q13541	EIF4EBP1	P28482	MAPK1	S112	G109C	109	Missense	distal	-3	no	8.221	7.707	EPSD	TCGA;COSMIC	8.102	Loss
CMGC_MAPK_ERK1_MAPK1_ST	Q13541	EIF4EBP1	P28482	MAPK1	S112	A107V	107	Missense	distal	-5	no	8.221	8.193	EPSD	TCGA;ICGC;COSMIC;GDSC;CCLE	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q96PH1	NOX5	P28482	MAPK1	S544	R542T	542	Missense	proximal	-2	no	9.731	8.850	EPSD	TCGA;COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q96PH1	NOX5	P28482	MAPK1	S544	S551Y	551	Missense	distal	7	no	9.731	10.248	EPSD	TCGA;COSMIC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q96PH1	NOX5	P28482	MAPK1	S544	G550S	550	Missense	distal	6	no	9.731	9.808	EPSD	TCGA;COSMIC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q96PH1	NOX5	P28482	MAPK1	S544	K543N	543	Missense	proximal	-1	no	9.731	9.723	EPSD	TCGA;ICGC;COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P50548	ERF	P28482	MAPK1	S21	P22R	22	Missense	proximal	1	no	16.292	6.638	EPSD	TCGA;ICGC	8.102	Loss
CMGC_MAPK_ERK1_MAPK1_ST	P50548	ERF	P28482	MAPK1	S21	W14R	14	Missense	distal	-7	no	16.292	16.343	EPSD	TCGA;ICGC;COSMIC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P50548	ERF	P28482	MAPK1	S24	P22R	22	Missense	proximal	-2	no	8.535	6.716	EPSD	TCGA;ICGC	8.102	Loss
CMGC_MAPK_ERK1_MAPK1_ST	P50548	ERF	P28482	MAPK1	S131	P133L	133	Missense	proximal	2	no	8.784	8.636	EPSD	TCGA	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P50548	ERF	P28482	MAPK1	S131	S131G	131	Missense	central	0	yes	8.784	0.000	EPSD	TCGA;COSMIC	8.102	Loss
CMGC_MAPK_ERK1_MAPK1_ST	P50548	ERF	P28482	MAPK1	T148	R143C	143	Missense	distal	-5	no	15.729	15.959	EPSD	TCGA;COSMIC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P50548	ERF	P28482	MAPK1	T148	T148M	148	Missense	central	0	yes	15.729	0.000	EPSD	TCGA;COSMIC	8.102	Loss
CMGC_MAPK_ERK1_MAPK1_ST	P50548	ERF	P28482	MAPK1	S154	T148M	148	Missense	distal	-6	no	16.150	16.116	EPSD	TCGA;COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P50548	ERF	P28482	MAPK1	S161	S168Y	168	Missense	distal	7	no	17.079	17.596	EPSD;PhosphoSitePlus	TCGA;COSMIC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P50548	ERF	P28482	MAPK1	S161	S168F	168	Missense	distal	7	no	17.079	17.426	EPSD;PhosphoSitePlus	TCGA;COSMIC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P50548	ERF	P28482	MAPK1	S246	P249T	249	Missense	distal	3	no	16.859	16.921	EPSD;PhosphoSitePlus	TCGA;COSMIC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P50548	ERF	P28482	MAPK1	S251	P249T	249	Missense	proximal	-2	no	16.663	13.964	EPSD;PhosphoSitePlus	TCGA;COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P50548	ERF	P28482	MAPK1	S327	R329H	329	Missense	proximal	2	no	13.656	13.413	EPSD	TCGA;COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P50548	ERF	P28482	MAPK1	S327	Y324N	324	Missense	distal	-3	no	13.656	13.940	EPSD	TCGA	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P50548	ERF	P28482	MAPK1	S327	A330T	330	Missense	distal	3	no	13.656	13.639	EPSD	TCGA;COSMIC;CCLE	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P50548	ERF	P28482	MAPK1	T357	S362F	362	Missense	distal	5	no	15.376	15.179	EPSD	TCGA;COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P50548	ERF	P28482	MAPK1	S363	S368F	368	Missense	distal	5	no	9.166	8.969	EPSD	TCGA;COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P50548	ERF	P28482	MAPK1	S363	S362F	362	Missense	proximal	-1	no	9.166	9.120	EPSD	TCGA;COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P50548	ERF	P28482	MAPK1	S363	S367F	367	Missense	distal	4	no	9.166	8.988	EPSD	TCGA;COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P50548	ERF	P28482	MAPK1	S367	S368F	368	Missense	proximal	1	no	5.601	8.426	EPSD	TCGA;COSMIC	8.102	Gain
CMGC_MAPK_ERK1_MAPK1_ST	P50548	ERF	P28482	MAPK1	S373	S368F	368	Missense	distal	-5	no	13.314	13.403	EPSD	TCGA;COSMIC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P50548	ERF	P28482	MAPK1	S373	S367F	367	Missense	distal	-6	no	13.314	13.230	EPSD	TCGA;COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P50548	ERF	P28482	MAPK1	T456	G451R	451	Missense	distal	-5	no	13.659	13.639	EPSD	TCGA;COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P50548	ERF	P28482	MAPK1	T526	P524A	524	Missense	proximal	-2	no	18.254	15.107	PhosphoSitePlus;EPSD	TCGA;COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P50548	ERF	P28482	MAPK1	S531	A537G	537	Missense	distal	6	no	8.319	8.538	EPSD	TCGA;COSMIC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P50548	ERF	P28482	MAPK1	S531	P524A	524	Missense	distal	-7	no	8.319	8.316	EPSD	TCGA;COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P50548	ERF	P28482	MAPK1	S532	A537G	537	Missense	distal	5	no	9.610	9.750	EPSD	TCGA;COSMIC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P50548	ERF	P28482	MAPK1	T538	L543P	543	Missense	distal	5	no	7.934	8.147	EPSD	TCGA;COSMIC	8.102	Gain
CMGC_MAPK_ERK1_MAPK1_ST	P50548	ERF	P28482	MAPK1	S542	A537G	537	Missense	distal	-5	no	8.178	8.121	EPSD	TCGA;COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P50548	ERF	P28482	MAPK1	S542	L543P	543	Missense	proximal	1	no	8.178	16.988	EPSD	TCGA;COSMIC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P50548	ERF	P28482	MAPK1	S542	S542A	542	Missense	central	0	yes	8.178	0.000	EPSD	TCGA;COSMIC	8.102	Loss
CMGC_MAPK_ERK1_MAPK1_ST	P49790	NUP153	P28482	MAPK1	T102	D98N	98	Missense	distal	-4	no	13.100	13.072	EPSD	TCGA;ICGC;COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P49790	NUP153	P28482	MAPK1	T102	G99E	99	Missense	distal	-3	no	13.100	13.109	EPSD	TCGA;ICGC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P49790	NUP153	P28482	MAPK1	T115	T116A	116	Missense	proximal	1	no	7.681	8.549	EPSD	TCGA;ICGC;COSMIC	8.102	Gain
CMGC_MAPK_ERK1_MAPK1_ST	P49790	NUP153	P28482	MAPK1	T118	A119T	119	Missense	proximal	1	no	8.475	7.607	EPSD	TCGA;ICGC	8.102	Loss
CMGC_MAPK_ERK1_MAPK1_ST	P49790	NUP153	P28482	MAPK1	T118	E111K	111	Missense	distal	-7	no	8.475	8.468	EPSD	TCGA;ICGC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P49790	NUP153	P28482	MAPK1	T118	T116A	116	Missense	proximal	-2	no	8.475	8.028	EPSD	TCGA;ICGC;COSMIC	8.102	Loss
CMGC_MAPK_ERK1_MAPK1_ST	P49790	NUP153	P28482	MAPK1	S209	P210T	210	Missense	proximal	1	no	15.688	7.189	EPSD	TCGA;ICGC;COSMIC	8.102	Loss
CMGC_MAPK_ERK1_MAPK1_ST	P49790	NUP153	P28482	MAPK1	S209	H216Y	216	Missense	distal	7	no	15.688	15.982	EPSD	TCGA;ICGC;COSMIC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P49790	NUP153	P28482	MAPK1	S209	S203L	203	Missense	distal	-6	no	15.688	15.622	EPSD	TCGA;ICGC;COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P49790	NUP153	P28482	MAPK1	S209	L207V	207	Missense	proximal	-2	no	15.688	15.732	EPSD	TCGA;ICGC;COSMIC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P49790	NUP153	P28482	MAPK1	S209	R214H	214	Missense	distal	5	no	15.688	15.511	EPSD	TCGA;ICGC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P49790	NUP153	P28482	MAPK1	S215	H216Y	216	Missense	proximal	1	no	7.410	8.225	EPSD	TCGA;ICGC;COSMIC	8.102	Gain
CMGC_MAPK_ERK1_MAPK1_ST	P49790	NUP153	P28482	MAPK1	S240	G237E	237	Missense	distal	-3	no	13.530	13.539	EPSD	TCGA;ICGC;COSMIC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P49790	NUP153	P28482	MAPK1	S240	S247L	247	Missense	distal	7	no	13.530	13.819	EPSD	TCGA;ICGC;COSMIC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P49790	NUP153	P28482	MAPK1	S240	S240F	240	Missense	central	0	yes	13.530	0.000	EPSD	TCGA;ICGC;COSMIC	8.102	Loss
CMGC_MAPK_ERK1_MAPK1_ST	P49790	NUP153	P28482	MAPK1	S257	P261T	261	Missense	distal	4	no	12.768	12.644	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P49790	NUP153	P28482	MAPK1	S257	P261S	261	Missense	distal	4	no	12.768	12.757	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P49790	NUP153	P28482	MAPK1	S257	P258S	258	Missense	proximal	1	no	12.768	3.373	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	8.102	Loss
CMGC_MAPK_ERK1_MAPK1_ST	P49790	NUP153	P28482	MAPK1	S320	E316Q	316	Missense	distal	-4	no	14.053	13.889	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P49790	NUP153	P28482	MAPK1	S320	R327K	327	Missense	distal	7	no	14.053	13.998	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P49790	NUP153	P28482	MAPK1	S320	R327I	327	Missense	distal	7	no	14.053	14.597	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P49790	NUP153	P28482	MAPK1	S334	L336V	336	Missense	proximal	2	no	12.980	13.074	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P49790	NUP153	P28482	MAPK1	S334	R327K	327	Missense	distal	-7	no	12.980	12.983	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P49790	NUP153	P28482	MAPK1	S334	R327I	327	Missense	distal	-7	no	12.980	12.953	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P49790	NUP153	P28482	MAPK1	S338	L336V	336	Missense	proximal	-2	no	15.032	15.077	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P49790	NUP153	P28482	MAPK1	T369	P363S	363	Missense	distal	-6	no	16.319	16.293	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P49790	NUP153	P28482	MAPK1	S374	K371E	371	Missense	distal	-3	no	8.568	8.646	EPSD	TCGA;ICGC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P49790	NUP153	P28482	MAPK1	S374	S380I	380	Missense	distal	6	no	8.568	7.901	EPSD	TCGA;ICGC;COSMIC	8.102	Loss
CMGC_MAPK_ERK1_MAPK1_ST	P49790	NUP153	P28482	MAPK1	S374	R379Q	379	Missense	distal	5	no	8.568	8.398	EPSD	TCGA;ICGC;COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P49790	NUP153	P28482	MAPK1	T388	L387V	387	Missense	proximal	-1	no	12.686	12.719	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P49790	NUP153	P28482	MAPK1	T388	S386Y	386	Missense	proximal	-2	no	12.686	13.402	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P49790	NUP153	P28482	MAPK1	S491	P492S	492	Missense	proximal	1	no	13.237	3.842	EPSD	TCGA;ICGC;COSMIC	8.102	Loss
CMGC_MAPK_ERK1_MAPK1_ST	P49790	NUP153	P28482	MAPK1	S491	S491F	491	Missense	central	0	yes	13.237	0.000	EPSD	TCGA;ICGC;COSMIC	8.102	Loss
CMGC_MAPK_ERK1_MAPK1_ST	P49790	NUP153	P28482	MAPK1	S491	E493D	493	Missense	proximal	2	no	13.237	13.289	EPSD	TCGA;ICGC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P49790	NUP153	P28482	MAPK1	S498	P492S	492	Missense	distal	-6	no	10.870	10.843	EPSD	TCGA;ICGC;COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P49790	NUP153	P28482	MAPK1	S498	S491F	491	Missense	distal	-7	no	10.870	10.849	EPSD	TCGA;ICGC;COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P49790	NUP153	P28482	MAPK1	S498	S504L	504	Missense	distal	6	no	10.870	10.463	EPSD	TCGA;ICGC;COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P49790	NUP153	P28482	MAPK1	S498	E493D	493	Missense	distal	-5	no	10.870	10.914	EPSD	TCGA;ICGC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P49790	NUP153	P28482	MAPK1	S500	S504L	504	Missense	distal	4	no	14.210	14.101	EPSD	TCGA;ICGC;COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P49790	NUP153	P28482	MAPK1	S500	E493D	493	Missense	distal	-7	no	14.210	14.202	EPSD	TCGA;ICGC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P49790	NUP153	P28482	MAPK1	S516	S516C	516	Missense	central	0	yes	12.515	0.000	PhosphoSitePlus;EPSD	TCGA;ICGC;COSMIC	8.102	Loss
CMGC_MAPK_ERK1_MAPK1_ST	P49790	NUP153	P28482	MAPK1	S516	P517L	517	Missense	proximal	1	no	12.515	3.706	PhosphoSitePlus;EPSD	TCGA;ICGC;COSMIC	8.102	Loss
CMGC_MAPK_ERK1_MAPK1_ST	P49790	NUP153	P28482	MAPK1	S522	S516C	516	Missense	distal	-6	no	14.700	14.559	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P49790	NUP153	P28482	MAPK1	S522	P517L	517	Missense	distal	-5	no	14.700	14.849	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P49790	NUP153	P28482	MAPK1	S522	F527C	527	Missense	distal	5	no	14.700	14.497	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P49790	NUP153	P28482	MAPK1	S529	P530L	530	Missense	proximal	1	no	14.304	5.494	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	8.102	Loss
CMGC_MAPK_ERK1_MAPK1_ST	P49790	NUP153	P28482	MAPK1	S529	F527C	527	Missense	proximal	-2	no	14.304	13.178	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P49790	NUP153	P28482	MAPK1	T588	K587N	587	Missense	proximal	-1	no	12.606	12.598	EPSD	TCGA;ICGC;COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P49790	NUP153	P28482	MAPK1	S614	A618T	618	Missense	distal	4	no	14.401	14.381	EPSD	TCGA;ICGC;COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P49790	NUP153	P28482	MAPK1	S619	A618T	618	Missense	proximal	-1	no	13.227	13.222	EPSD	TCGA;ICGC;COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P49790	NUP153	P28482	MAPK1	S633	T632R	632	Missense	proximal	-1	no	13.432	13.454	EPSD	TCGA;ICGC;COSMIC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P49790	NUP153	P28482	MAPK1	S633	A631T	631	Missense	proximal	-2	no	13.432	13.879	EPSD	TCGA;ICGC;COSMIC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P49790	NUP153	P28482	MAPK1	T699	N701S	701	Missense	proximal	2	no	16.577	16.625	EPSD	TCGA;ICGC;COSMIC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P49790	NUP153	P28482	MAPK1	T747	P748S	748	Missense	proximal	1	no	12.493	3.098	EPSD	TCGA;ICGC;COSMIC	8.102	Loss
CMGC_MAPK_ERK1_MAPK1_ST	P49790	NUP153	P28482	MAPK1	T747	C745G	745	Missense	proximal	-2	no	12.493	13.065	EPSD	TCGA	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P49790	NUP153	P28482	MAPK1	T996	S1003Y	1003	Missense	distal	7	no	11.873	12.390	EPSD	TCGA;ICGC;COSMIC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P49790	NUP153	P28482	MAPK1	T996	P992Q	992	Missense	distal	-4	no	11.873	11.680	EPSD	TCGA	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P49790	NUP153	P28482	MAPK1	T1032	A1036T	1036	Missense	distal	4	no	12.934	12.914	EPSD	TCGA	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P49790	NUP153	P28482	MAPK1	T1032	G1025S	1025	Missense	distal	-7	no	12.934	12.948	EPSD	TCGA;ICGC;COSMIC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P49790	NUP153	P28482	MAPK1	T1032	P1035L	1035	Missense	distal	3	no	12.934	13.024	EPSD	TCGA;ICGC;COSMIC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P49790	NUP153	P28482	MAPK1	T1032	S1031A	1031	Missense	proximal	-1	no	12.934	12.941	EPSD	TCGA;ICGC;COSMIC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P49790	NUP153	P28482	MAPK1	T1032	G1027D	1027	Missense	distal	-5	no	12.934	12.936	EPSD	TCGA;ICGC;COSMIC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P49790	NUP153	P28482	MAPK1	S1461	S1457C	1457	Missense	distal	-4	no	8.528	7.884	EPSD	TCGA;ICGC;COSMIC	8.102	Loss
CMGC_MAPK_ERK1_MAPK1_ST	P49790	NUP153	P28482	MAPK1	S1461	F1462L	1462	Missense	proximal	1	no	8.528	6.288	EPSD	TCGA;ICGC;COSMIC	8.102	Loss
CMGC_MAPK_ERK1_MAPK1_ST	Q16690	DUSP5	P28482	MAPK1	T321	E314K	314	Missense	distal	-7	no	15.882	15.875	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC;GDSC;CCLE	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q16690	DUSP5	P28482	MAPK1	T321	E316D	316	Missense	distal	-5	no	15.882	15.927	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q16690	DUSP5	P28482	MAPK1	S346	G340C	340	Missense	distal	-6	no	15.013	14.890	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC;CCLE	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q16690	DUSP5	P28482	MAPK1	S376	E372K	372	Missense	distal	-4	no	15.037	15.055	PhosphoSitePlus;EPSD	TCGA;ICGC;COSMIC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q16690	DUSP5	P28482	MAPK1	S376	A381V	381	Missense	distal	5	no	15.037	15.054	PhosphoSitePlus;EPSD	TCGA;ICGC;COSMIC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q16690	DUSP5	P28482	MAPK1	S376	T380M	380	Missense	distal	4	no	15.037	14.962	PhosphoSitePlus;EPSD	TCGA;ICGC;COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	O95863	SNAI1	P28482	MAPK1	S82	R78Q	78	Missense	distal	-4	no	12.900	12.796	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	O95863	SNAI1	P28482	MAPK1	S107	P110S	110	Missense	distal	3	no	18.336	18.405	EPSD	TCGA;ICGC;COSMIC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	O95863	SNAI1	P28482	MAPK1	S107	S114F	114	Missense	distal	7	no	18.336	18.684	EPSD	TCGA;ICGC;COSMIC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	O95863	SNAI1	P28482	MAPK1	S112	S119F	119	Missense	distal	7	no	10.083	10.430	EPSD	TCGA;ICGC;COSMIC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	O95863	SNAI1	P28482	MAPK1	S112	P110S	110	Missense	proximal	-2	no	10.083	7.249	EPSD	TCGA;ICGC;COSMIC	8.102	Loss
CMGC_MAPK_ERK1_MAPK1_ST	O95863	SNAI1	P28482	MAPK1	S112	S114F	114	Missense	proximal	2	no	10.083	9.951	EPSD	TCGA;ICGC;COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	O95863	SNAI1	P28482	MAPK1	S112	S115F	115	Missense	distal	3	no	10.083	10.145	EPSD	TCGA;ICGC;COSMIC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	O95863	SNAI1	P28482	MAPK1	S246	R247P	247	Missense	proximal	1	no	6.421	16.075	EPSD	TCGA;ICGC;COSMIC	8.102	Gain
CMGC_MAPK_ERK1_MAPK1_ST	P35568	IRS1	P28482	MAPK1	S281	C276F	276	Missense	distal	-5	no	8.330	8.215	EPSD	TCGA;ICGC;COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P35568	IRS1	P28482	MAPK1	S281	R285H	285	Missense	distal	4	no	8.330	8.189	EPSD	TCGA;ICGC;COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P35568	IRS1	P28482	MAPK1	S281	N275S	275	Missense	distal	-6	no	8.330	8.327	EPSD	TCGA;ICGC;COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P35568	IRS1	P28482	MAPK1	S281	R285C	285	Missense	distal	4	no	8.330	8.071	EPSD	TCGA;ICGC;COSMIC	8.102	Loss
CMGC_MAPK_ERK1_MAPK1_ST	P35568	IRS1	P28482	MAPK1	S312	A314G	314	Missense	proximal	2	no	12.828	12.976	EPSD	TCGA;ICGC;COSMIC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P35568	IRS1	P28482	MAPK1	S323	R327H	327	Missense	distal	4	no	10.184	10.042	EPSD	TCGA;ICGC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P35568	IRS1	P28482	MAPK1	S323	A328T	328	Missense	distal	5	no	10.184	10.269	EPSD	TCGA;ICGC;COSMIC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P35568	IRS1	P28482	MAPK1	S323	S330N	330	Missense	distal	7	no	10.184	10.166	EPSD	TCGA;ICGC;COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P35568	IRS1	P28482	MAPK1	S323	S323A	323	Missense	central	0	yes	10.184	0.000	EPSD	TCGA;ICGC;COSMIC	8.102	Loss
CMGC_MAPK_ERK1_MAPK1_ST	P35568	IRS1	P28482	MAPK1	S323	P321L	321	Missense	proximal	-2	no	10.184	8.266	EPSD	TCGA;ICGC;COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P35568	IRS1	P28482	MAPK1	S345	R338H	338	Missense	distal	-7	no	14.233	14.222	EPSD	TCGA;ICGC;COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P35568	IRS1	P28482	MAPK1	S345	R338C	338	Missense	distal	-7	no	14.233	14.201	EPSD	TCGA;ICGC;COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P35568	IRS1	P28482	MAPK1	S345	P346H	346	Missense	proximal	1	no	14.233	6.409	EPSD	TCGA;ICGC	8.102	Loss
CMGC_MAPK_ERK1_MAPK1_ST	P35568	IRS1	P28482	MAPK1	S348	P346H	346	Missense	proximal	-2	no	17.404	14.649	EPSD	TCGA;ICGC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P35568	IRS1	P28482	MAPK1	T354	A356T	356	Missense	proximal	2	no	8.140	8.219	EPSD	TCGA;ICGC;COSMIC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P35568	IRS1	P28482	MAPK1	T354	R360W	360	Missense	distal	6	no	8.140	7.217	EPSD	TCGA;ICGC;CCLE	8.102	Loss
CMGC_MAPK_ERK1_MAPK1_ST	P35568	IRS1	P28482	MAPK1	T354	H359R	359	Missense	distal	5	no	8.140	8.317	EPSD	TCGA;ICGC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P35568	IRS1	P28482	MAPK1	S362	A363D	363	Missense	proximal	1	no	8.870	7.804	EPSD	TCGA;ICGC;COSMIC	8.102	Loss
CMGC_MAPK_ERK1_MAPK1_ST	P35568	IRS1	P28482	MAPK1	S362	A356T	356	Missense	distal	-6	no	8.870	8.859	EPSD	TCGA;ICGC;COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P35568	IRS1	P28482	MAPK1	S362	A363T	363	Missense	proximal	1	no	8.870	8.001	EPSD	TCGA;ICGC;COSMIC	8.102	Loss
CMGC_MAPK_ERK1_MAPK1_ST	P35568	IRS1	P28482	MAPK1	S362	R360W	360	Missense	proximal	-2	no	8.870	7.947	EPSD	TCGA;ICGC;CCLE	8.102	Loss
CMGC_MAPK_ERK1_MAPK1_ST	P35568	IRS1	P28482	MAPK1	S362	H359R	359	Missense	distal	-3	no	8.870	9.200	EPSD	TCGA;ICGC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P35568	IRS1	P28482	MAPK1	S380	R381H	381	Missense	proximal	1	no	6.452	8.283	EPSD	TCGA	8.102	Gain
CMGC_MAPK_ERK1_MAPK1_ST	P35568	IRS1	P28482	MAPK1	S383	P389L	389	Missense	distal	6	no	15.450	15.044	EPSD	TCGA;ICGC;COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P35568	IRS1	P28482	MAPK1	S383	R381H	381	Missense	proximal	-2	no	15.450	14.514	EPSD	TCGA	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P35568	IRS1	P28482	MAPK1	S383	P384H	384	Missense	proximal	1	no	15.450	7.626	EPSD	TCGA;ICGC;COSMIC	8.102	Loss
CMGC_MAPK_ERK1_MAPK1_ST	P35568	IRS1	P28482	MAPK1	S383	P378S	378	Missense	distal	-5	no	15.450	15.524	EPSD	TCGA;ICGC;COSMIC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P35568	IRS1	P28482	MAPK1	S388	P389L	389	Missense	proximal	1	no	13.356	4.546	EPSD	TCGA;ICGC;COSMIC	8.102	Loss
CMGC_MAPK_ERK1_MAPK1_ST	P35568	IRS1	P28482	MAPK1	S388	R381H	381	Missense	distal	-7	no	13.356	13.344	EPSD	TCGA	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P35568	IRS1	P28482	MAPK1	S388	S395C	395	Missense	distal	7	no	13.356	14.015	EPSD	TCGA;ICGC;COSMIC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P35568	IRS1	P28482	MAPK1	S388	P384H	384	Missense	distal	-4	no	13.356	13.114	EPSD	TCGA;ICGC;COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P35568	IRS1	P28482	MAPK1	S419	G424S	424	Missense	distal	5	no	12.815	12.834	EPSD	TCGA;ICGC;COSMIC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P35568	IRS1	P28482	MAPK1	S434	S428L	428	Missense	distal	-6	no	13.960	13.894	EPSD	TCGA;ICGC;COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P35568	IRS1	P28482	MAPK1	S434	F438V	438	Missense	distal	4	no	13.960	14.038	EPSD	TCGA;ICGC;COSMIC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P35568	IRS1	P28482	MAPK1	T446	V445I	445	Missense	proximal	-1	no	13.754	13.714	EPSD	TCGA;ICGC;COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P35568	IRS1	P28482	MAPK1	T446	R443H	443	Missense	distal	-3	no	13.754	13.425	EPSD	TCGA;ICGC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P35568	IRS1	P28482	MAPK1	T475	G469C	469	Missense	distal	-6	no	8.501	8.377	EPSD	TCGA;ICGC;COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P35568	IRS1	P28482	MAPK1	T495	T498I	498	Missense	distal	3	no	15.028	15.094	EPSD	TCGA;ICGC;COSMIC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P35568	IRS1	P28482	MAPK1	T495	G489C	489	Missense	distal	-6	no	15.028	14.904	EPSD	TCGA;ICGC;COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P35568	IRS1	P28482	MAPK1	T495	G488V	488	Missense	distal	-7	no	15.028	15.027	EPSD	TCGA;ICGC;COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P35568	IRS1	P28482	MAPK1	S503	T498I	498	Missense	distal	-5	no	11.520	11.626	EPSD	TCGA;ICGC;COSMIC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P35568	IRS1	P28482	MAPK1	S503	P504A	504	Missense	proximal	1	no	11.520	3.889	EPSD	TCGA;ICGC;COSMIC	8.102	Loss
CMGC_MAPK_ERK1_MAPK1_ST	P35568	IRS1	P28482	MAPK1	S513	R520W	520	Missense	distal	7	no	7.995	8.967	EPSD	TCGA;ICGC;COSMIC	8.102	Gain
CMGC_MAPK_ERK1_MAPK1_ST	P35568	IRS1	P28482	MAPK1	S513	R520Q	520	Missense	distal	7	no	7.995	8.110	EPSD	TCGA;ICGC;COSMIC	8.102	Gain
CMGC_MAPK_ERK1_MAPK1_ST	P35568	IRS1	P28482	MAPK1	S604	G611C	611	Missense	distal	7	no	7.844	8.435	EPSD	TCGA;ICGC;COSMIC	8.102	Gain
CMGC_MAPK_ERK1_MAPK1_ST	P35568	IRS1	P28482	MAPK1	S616	G611C	611	Missense	distal	-5	no	16.452	16.662	EPSD	TCGA;ICGC;COSMIC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P35568	IRS1	P28482	MAPK1	S666	S672C	672	Missense	distal	6	no	10.492	9.625	EPSD	TCGA;ICGC;COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P35568	IRS1	P28482	MAPK1	S672	I675V	675	Missense	distal	3	no	13.704	13.634	EPSD	TCGA;ICGC;COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P35568	IRS1	P28482	MAPK1	S672	G676E	676	Missense	distal	4	no	13.704	13.726	EPSD	TCGA	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P35568	IRS1	P28482	MAPK1	S672	S672C	672	Missense	central	0	yes	13.704	0.000	EPSD	TCGA;ICGC;COSMIC	8.102	Loss
CMGC_MAPK_ERK1_MAPK1_ST	P35568	IRS1	P28482	MAPK1	S736	M733I	733	Missense	distal	-3	no	13.268	13.264	EPSD	TCGA;ICGC;COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P35568	IRS1	P28482	MAPK1	S736	N742D	742	Missense	distal	6	no	13.268	13.318	EPSD	TCGA;ICGC;COSMIC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P35568	IRS1	P28482	MAPK1	S736	D731E	731	Missense	distal	-5	no	13.268	13.223	EPSD	TCGA;ICGC;COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P35568	IRS1	P28482	MAPK1	S745	N742D	742	Missense	distal	-3	no	12.472	12.504	EPSD	TCGA;ICGC;COSMIC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P35568	IRS1	P28482	MAPK1	S892	P890S	890	Missense	proximal	-2	no	17.786	14.952	EPSD	TCGA;ICGC;COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P35568	IRS1	P28482	MAPK1	S1005	S1005L	1005	Missense	central	0	yes	12.461	0.000	EPSD	TCGA;ICGC	8.102	Loss
CMGC_MAPK_ERK1_MAPK1_ST	P35568	IRS1	P28482	MAPK1	S1043	P1047S	1047	Missense	distal	4	no	12.161	12.151	EPSD	TCGA;ICGC;COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P35568	IRS1	P28482	MAPK1	S1078	R1081H	1081	Missense	distal	3	no	12.871	12.914	EPSD	TCGA;ICGC;COSMIC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P35568	IRS1	P28482	MAPK1	T1107	S1109C	1109	Missense	proximal	2	no	12.379	12.147	EPSD	TCGA;ICGC;COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P35568	IRS1	P28482	MAPK1	S1222	S1223G	1223	Missense	proximal	1	no	8.279	7.609	EPSD	TCGA;ICGC;COSMIC	8.102	Loss
CMGC_MAPK_ERK1_MAPK1_ST	P35568	IRS1	P28482	MAPK1	S1223	S1223G	1223	Missense	central	0	yes	8.399	0.000	EPSD	TCGA;ICGC;COSMIC	8.102	Loss
CMGC_MAPK_ERK1_MAPK1_ST	P35568	IRS1	P28482	MAPK1	S1227	S1223G	1223	Missense	distal	-4	no	9.189	8.922	EPSD	TCGA;ICGC;COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P35568	IRS1	P28482	MAPK1	S1227	S1233G	1233	Missense	distal	6	no	9.189	9.111	EPSD	TCGA;ICGC;COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	O00213	APBB1	P28482	MAPK1	S175	E181D	181	Missense	distal	6	no	16.369	16.290	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	O00213	APBB1	P28482	MAPK1	S287	P288L	288	Missense	proximal	1	no	17.229	8.419	EPSD;PhosphoSitePlus	TCGA;COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	O00213	APBB1	P28482	MAPK1	S287	G284V	284	Missense	distal	-3	no	17.229	17.110	EPSD;PhosphoSitePlus	TCGA	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	O00213	APBB1	P28482	MAPK1	S287	R285W	285	Missense	proximal	-2	no	17.229	16.306	EPSD;PhosphoSitePlus	TCGA;COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	O00213	APBB1	P28482	MAPK1	S287	P288S	288	Missense	proximal	1	no	17.229	7.834	EPSD;PhosphoSitePlus	TCGA;COSMIC	8.102	Loss
CMGC_MAPK_ERK1_MAPK1_ST	O00213	APBB1	P28482	MAPK1	S287	G284S	284	Missense	distal	-3	no	17.229	17.241	EPSD;PhosphoSitePlus	TCGA;COSMIC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	O00213	APBB1	P28482	MAPK1	S345	A343T	343	Missense	proximal	-2	no	7.745	8.192	EPSD	TCGA;COSMIC	8.102	Gain
CMGC_MAPK_ERK1_MAPK1_ST	O00213	APBB1	P28482	MAPK1	S347	Q353H	353	Missense	distal	6	no	15.884	15.866	EPSD;PhosphoSitePlus	TCGA;COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	O00213	APBB1	P28482	MAPK1	S347	Q344H	344	Missense	distal	-3	no	15.884	15.831	EPSD;PhosphoSitePlus	TCGA;COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	O00213	APBB1	P28482	MAPK1	S347	P350L	350	Missense	distal	3	no	15.884	15.974	EPSD;PhosphoSitePlus	TCGA;COSMIC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	O00213	APBB1	P28482	MAPK1	S347	A343T	343	Missense	distal	-4	no	15.884	15.864	EPSD;PhosphoSitePlus	TCGA;COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P49023	PXN	P28482	MAPK1	S26	E27G	27	Missense	proximal	1	no	9.197	7.903	EPSD	TCGA	8.102	Loss
CMGC_MAPK_ERK1_MAPK1_ST	P49023	PXN	P28482	MAPK1	S26	R21W	21	Missense	distal	-5	no	9.197	9.473	EPSD	TCGA	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P49023	PXN	P28482	MAPK1	T29	E27G	27	Missense	proximal	-2	no	15.492	14.678	EPSD	TCGA	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P49023	PXN	P28482	MAPK1	S32	E27G	27	Missense	distal	-5	no	10.334	10.377	EPSD	TCGA	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P49023	PXN	P28482	MAPK1	S119	Q124H	124	Missense	distal	5	no	9.007	9.001	EPSD	TCGA;COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P49023	PXN	P28482	MAPK1	S130	M134I	134	Missense	distal	4	no	14.828	14.850	EPSD;PhosphoSitePlus	TCGA;COSMIC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P49023	PXN	P28482	MAPK1	S130	E128K	128	Missense	proximal	-2	no	14.828	14.789	EPSD;PhosphoSitePlus	TCGA;COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P49023	PXN	P28482	MAPK1	S130	Q124H	124	Missense	distal	-6	no	14.828	14.769	EPSD;PhosphoSitePlus	TCGA;COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P49023	PXN	P28482	MAPK1	S188	S188N	188	Missense	central	0	yes	14.683	0.000	EPSD	TCGA	8.102	Loss
CMGC_MAPK_ERK1_MAPK1_ST	P49023	PXN	P28482	MAPK1	S226	S227F	227	Missense	proximal	1	no	5.540	8.366	EPSD	TCGA;COSMIC	8.102	Gain
CMGC_MAPK_ERK1_MAPK1_ST	P49023	PXN	P28482	MAPK1	S230	S227F	227	Missense	distal	-3	no	11.912	11.679	EPSD	TCGA;COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P49023	PXN	P28482	MAPK1	S230	V237A	237	Missense	distal	7	no	11.912	11.810	EPSD	TCGA	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P49023	PXN	P28482	MAPK1	S244	V248I	248	Missense	distal	4	no	10.500	10.433	EPSD	TCGA;COSMIC;CCLE	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P49023	PXN	P28482	MAPK1	S244	R247H	247	Missense	distal	3	no	10.500	10.543	EPSD	TCGA;COSMIC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P49023	PXN	P28482	MAPK1	S244	V237A	237	Missense	distal	-7	no	10.500	10.517	EPSD	TCGA	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P14618	PKM	P28482	MAPK1	T15	F12Y	12	Missense	distal	-3	no	8.640	8.603	EPSD	TCGA;ICGC;COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P14618	PKM	P28482	MAPK1	T25	R32C	32	Missense	distal	7	no	7.764	8.419	EPSD	TCGA;ICGC;COSMIC	8.102	Gain
CMGC_MAPK_ERK1_MAPK1_ST	P14618	PKM	P28482	MAPK1	S37	R43P	43	Missense	distal	6	no	14.625	14.732	PhosphoSitePlus	TCGA;ICGC;COSMIC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P14618	PKM	P28482	MAPK1	S37	R32C	32	Missense	distal	-5	no	14.625	14.855	PhosphoSitePlus	TCGA;ICGC;COSMIC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P14618	PKM	P28482	MAPK1	S37	R32H	32	Missense	distal	-5	no	14.625	14.702	PhosphoSitePlus	TCGA;ICGC;COSMIC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P14618	PKM	P28482	MAPK1	T41	R43P	43	Missense	proximal	2	no	9.115	9.001	EPSD	TCGA;ICGC;COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P14618	PKM	P28482	MAPK1	T41	G46V	46	Missense	distal	5	no	9.115	8.991	EPSD	TCGA;ICGC;COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P14618	PKM	P28482	MAPK1	T143	L144P	144	Missense	proximal	1	no	3.157	11.967	EPSD	TCGA;ICGC;COSMIC	8.102	Gain
CMGC_MAPK_ERK1_MAPK1_ST	P14618	PKM	P28482	MAPK1	S420	V417L	417	Missense	distal	-3	no	12.118	12.041	EPSD	TCGA;ICGC;COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q09472	EP300	P28482	MAPK1	S12	K14Q	14	Missense	proximal	2	no	10.311	10.201	EPSD	TCGA;ICGC;COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q09472	EP300	P28482	MAPK1	S12	K17E	17	Missense	distal	5	no	10.311	10.371	EPSD	TCGA;ICGC;COSMIC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q09472	EP300	P28482	MAPK1	S12	E7G	7	Missense	distal	-5	no	10.311	10.354	EPSD	TCGA;ICGC;COSMIC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q09472	EP300	P28482	MAPK1	S20	K14Q	14	Missense	distal	-6	no	17.537	17.536	EPSD	TCGA;ICGC;COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q09472	EP300	P28482	MAPK1	S20	K17E	17	Missense	distal	-3	no	17.537	17.615	EPSD	TCGA;ICGC;COSMIC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q09472	EP300	P28482	MAPK1	S20	A25P	25	Missense	distal	5	no	17.537	17.678	EPSD	TCGA;ICGC;COSMIC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q09472	EP300	P28482	MAPK1	S20	P21A	21	Missense	proximal	1	no	17.537	9.906	EPSD	TCGA;ICGC;COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q09472	EP300	P28482	MAPK1	S24	K17E	17	Missense	distal	-7	no	9.677	9.684	EPSD	TCGA;ICGC;COSMIC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q09472	EP300	P28482	MAPK1	S24	A25P	25	Missense	proximal	1	no	9.677	17.307	EPSD	TCGA;ICGC;COSMIC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q09472	EP300	P28482	MAPK1	S24	P21A	21	Missense	distal	-3	no	9.677	9.310	EPSD	TCGA;ICGC;COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q09472	EP300	P28482	MAPK1	S26	A25P	25	Missense	proximal	-1	no	8.548	8.585	EPSD	TCGA;ICGC;COSMIC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q09472	EP300	P28482	MAPK1	S26	P21A	21	Missense	distal	-5	no	8.548	8.673	EPSD	TCGA;ICGC;COSMIC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q09472	EP300	P28482	MAPK1	S26	F33V	33	Missense	distal	7	no	8.548	8.483	EPSD	TCGA;ICGC;COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q09472	EP300	P28482	MAPK1	S28	A25P	25	Missense	distal	-3	no	8.492	8.859	EPSD	TCGA;ICGC;COSMIC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q09472	EP300	P28482	MAPK1	S28	P21A	21	Missense	distal	-7	no	8.492	8.489	EPSD	TCGA;ICGC;COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q09472	EP300	P28482	MAPK1	S28	F33V	33	Missense	distal	5	no	8.492	8.546	EPSD	TCGA;ICGC;COSMIC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q09472	EP300	P28482	MAPK1	S90	N94S	94	Missense	distal	4	no	13.019	13.056	EPSD	TCGA;ICGC;COSMIC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q09472	EP300	P28482	MAPK1	S90	L84S	84	Missense	distal	-6	no	13.019	13.085	EPSD	TCGA;COSMIC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q09472	EP300	P28482	MAPK1	S90	R86Q	86	Missense	distal	-4	no	13.019	12.916	EPSD	TCGA;ICGC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q09472	EP300	P28482	MAPK1	S112	N119K	119	Missense	distal	7	no	13.300	13.265	EPSD	TCGA;ICGC;COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q09472	EP300	P28482	MAPK1	S112	G114E	114	Missense	proximal	2	no	13.300	13.214	EPSD	TCGA;ICGC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q09472	EP300	P28482	MAPK1	S255	Y257D	257	Missense	proximal	2	no	15.083	15.263	EPSD	TCGA;ICGC;COSMIC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q09472	EP300	P28482	MAPK1	S255	N249S	249	Missense	distal	-6	no	15.083	15.080	EPSD	TCGA;ICGC;COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q09472	EP300	P28482	MAPK1	S255	T258I	258	Missense	distal	3	no	15.083	15.149	EPSD	TCGA;ICGC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q09472	EP300	P28482	MAPK1	T317	P318A	318	Missense	proximal	1	no	14.325	6.694	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	8.102	Loss
CMGC_MAPK_ERK1_MAPK1_ST	Q09472	EP300	P28482	MAPK1	T317	Q312H	312	Missense	distal	-5	no	14.325	14.324	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q09472	EP300	P28482	MAPK1	S499	R504L	504	Missense	distal	5	no	12.989	12.726	EPSD	TCGA;ICGC;COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q09472	EP300	P28482	MAPK1	S499	P500L	500	Missense	proximal	1	no	12.989	4.180	EPSD	TCGA;ICGC;COSMIC	8.102	Loss
CMGC_MAPK_ERK1_MAPK1_ST	Q09472	EP300	P28482	MAPK1	S831	H828Y	828	Missense	distal	-3	no	12.213	12.117	EPSD	TCGA;ICGC;COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q09472	EP300	P28482	MAPK1	S831	S833L	833	Missense	proximal	2	no	12.213	12.093	EPSD	TCGA;ICGC;COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q09472	EP300	P28482	MAPK1	S833	H828Y	828	Missense	distal	-5	no	13.457	13.537	EPSD	TCGA;ICGC;COSMIC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q09472	EP300	P28482	MAPK1	S833	S833L	833	Missense	central	0	yes	13.457	0.000	EPSD	TCGA;ICGC;COSMIC	8.102	Loss
CMGC_MAPK_ERK1_MAPK1_ST	Q09472	EP300	P28482	MAPK1	T839	S833L	833	Missense	distal	-6	no	14.395	14.330	EPSD	TCGA;ICGC;COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q09472	EP300	P28482	MAPK1	T865	P867S	867	Missense	proximal	2	no	14.040	14.012	EPSD	TCGA;ICGC;COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q09472	EP300	P28482	MAPK1	T938	P933L	933	Missense	distal	-5	no	15.126	15.275	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q09472	EP300	P28482	MAPK1	T1032	P1039L	1039	Missense	distal	7	no	7.886	8.185	EPSD	TCGA;ICGC;COSMIC	8.102	Gain
CMGC_MAPK_ERK1_MAPK1_ST	Q09472	EP300	P28482	MAPK1	S1038	P1039L	1039	Missense	proximal	1	no	14.385	5.575	EPSD	TCGA;ICGC;COSMIC	8.102	Loss
CMGC_MAPK_ERK1_MAPK1_ST	Q09472	EP300	P28482	MAPK1	S1038	K1045N	1045	Missense	distal	7	no	14.385	14.419	EPSD	TCGA;ICGC;COSMIC;CCLE	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q09472	EP300	P28482	MAPK1	S1318	R1312Q	1312	Missense	distal	-6	no	8.168	8.145	EPSD	TCGA;ICGC;COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q09472	EP300	P28482	MAPK1	S1849	Q1843P	1843	Missense	distal	-6	no	13.372	13.388	EPSD	TCGA;ICGC;COSMIC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q09472	EP300	P28482	MAPK1	T1857	T1864S	1864	Missense	distal	7	no	17.476	17.324	EPSD	TCGA;ICGC;COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q09472	EP300	P28482	MAPK1	T1865	T1864S	1864	Missense	proximal	-1	no	17.756	17.754	EPSD	TCGA;ICGC;COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q09472	EP300	P28482	MAPK1	T1906	Q1904P	1904	Missense	proximal	-2	no	11.793	14.787	EPSD	TCGA;ICGC;COSMIC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q09472	EP300	P28482	MAPK1	T1906	A1901V	1901	Missense	distal	-5	no	11.793	11.764	EPSD	TCGA;ICGC;COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q09472	EP300	P28482	MAPK1	T1909	Q1904P	1904	Missense	distal	-5	no	15.192	15.068	EPSD	TCGA;ICGC;COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q09472	EP300	P28482	MAPK1	T1960	P1958L	1958	Missense	proximal	-2	no	18.000	16.082	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q09472	EP300	P28482	MAPK1	T1960	M1962T	1962	Missense	proximal	2	no	18.000	18.140	EPSD;PhosphoSitePlus	TCGA	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q09472	EP300	P28482	MAPK1	S2279	M2284V	2284	Missense	distal	5	no	16.736	16.798	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q09472	EP300	P28482	MAPK1	S2309	R2308C	2308	Missense	proximal	-1	no	12.769	12.667	EPSD	TCGA;ICGC;COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q09472	EP300	P28482	MAPK1	S2315	R2308C	2308	Missense	distal	-7	no	15.570	15.538	PhosphoSitePlus;EPSD	TCGA;ICGC;COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q09472	EP300	P28482	MAPK1	S2315	R2317Q	2317	Missense	proximal	2	no	15.570	15.278	PhosphoSitePlus;EPSD	TCGA;ICGC;COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q09472	EP300	P28482	MAPK1	S2315	R2317L	2317	Missense	proximal	2	no	15.570	15.309	PhosphoSitePlus;EPSD	TCGA;ICGC;COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q09472	EP300	P28482	MAPK1	S2326	P2327H	2327	Missense	proximal	1	no	12.494	4.670	EPSD	TCGA;ICGC	8.102	Loss
CMGC_MAPK_ERK1_MAPK1_ST	Q09472	EP300	P28482	MAPK1	S2328	P2327H	2327	Missense	proximal	-1	no	15.428	15.386	EPSD	TCGA;ICGC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q09472	EP300	P28482	MAPK1	S2366	E2360G	2360	Missense	distal	-6	no	13.450	13.397	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q09472	EP300	P28482	MAPK1	S2366	S2366N	2366	Missense	central	0	yes	13.450	0.000	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	8.102	Loss
CMGC_MAPK_ERK1_MAPK1_ST	Q09472	EP300	P28482	MAPK1	S2366	D2368N	2368	Missense	proximal	2	no	13.450	13.390	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q09472	EP300	P28482	MAPK1	S2366	L2373I	2373	Missense	distal	7	no	13.450	13.710	EPSD;PhosphoSitePlus	TCGA;ICGC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P38936	CDKN1A	P28482	MAPK1	T57	G61V	61	Missense	distal	4	no	13.731	13.682	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P38936	CDKN1A	P28482	MAPK1	T57	E56K	56	Missense	proximal	-1	no	13.731	13.759	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P38936	CDKN1A	P28482	MAPK1	T57	P58L	58	Missense	proximal	1	no	13.731	4.922	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	8.102	Loss
CMGC_MAPK_ERK1_MAPK1_ST	P38936	CDKN1A	P28482	MAPK1	S98	R94W	94	Missense	distal	-4	no	14.815	13.872	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P38936	CDKN1A	P28482	MAPK1	S98	R93S	93	Missense	distal	-5	no	14.815	14.842	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P38936	CDKN1A	P28482	MAPK1	S98	R94P	94	Missense	distal	-4	no	14.815	14.905	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P38936	CDKN1A	P28482	MAPK1	S98	P95S	95	Missense	distal	-3	no	14.815	14.639	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P38936	CDKN1A	P28482	MAPK1	S130	D136H	136	Missense	distal	6	no	14.369	14.109	PhosphoSitePlus;EPSD	TCGA;ICGC;COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P38936	CDKN1A	P28482	MAPK1	S130	G132C	132	Missense	proximal	2	no	14.369	14.091	PhosphoSitePlus;EPSD	TCGA;ICGC;COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P38936	CDKN1A	P28482	MAPK1	S130	E128K	128	Missense	proximal	-2	no	14.369	14.329	PhosphoSitePlus;EPSD	TCGA;ICGC;COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P38936	CDKN1A	P28482	MAPK1	S130	G135A	135	Missense	distal	5	no	14.369	14.228	PhosphoSitePlus;EPSD	TCGA	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P38936	CDKN1A	P28482	MAPK1	S137	G132C	132	Missense	distal	-5	no	7.997	8.206	EPSD	TCGA;ICGC;COSMIC	8.102	Gain
CMGC_MAPK_ERK1_MAPK1_ST	P07101	TH	P28482	MAPK1	T3	P4L	4	Missense	proximal	1	no	11.473	2.663	EPSD	TCGA;ICGC;COSMIC;GDSC;CCLE	8.102	Loss
CMGC_MAPK_ERK1_MAPK1_ST	P07101	TH	P28482	MAPK1	T8	R15H	15	Missense	distal	7	no	13.715	13.934	EPSD	TCGA;ICGC;COSMIC;GDSC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P07101	TH	P28482	MAPK1	T8	P4L	4	Missense	distal	-4	no	13.715	13.410	EPSD	TCGA;ICGC;COSMIC;GDSC;CCLE	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P07101	TH	P28482	MAPK1	S62	R64W	64	Missense	proximal	2	no	16.623	16.254	EPSD;PhosphoSitePlus	TCGA;COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P07101	TH	P28482	MAPK1	S62	P63T	63	Missense	proximal	1	no	16.623	8.124	EPSD;PhosphoSitePlus	TCGA;COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P07101	TH	P28482	MAPK1	S62	P63L	63	Missense	proximal	1	no	16.623	7.813	EPSD;PhosphoSitePlus	TCGA;COSMIC	8.102	Loss
CMGC_MAPK_ERK1_MAPK1_ST	P07101	TH	P28482	MAPK1	S62	P63S	63	Missense	proximal	1	no	16.623	7.228	EPSD;PhosphoSitePlus	TCGA;COSMIC	8.102	Loss
CMGC_MAPK_ERK1_MAPK1_ST	P07101	TH	P28482	MAPK1	S118	S125L	125	Missense	distal	7	no	14.340	14.628	EPSD	TCGA;COSMIC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P07101	TH	P28482	MAPK1	S118	R120M	120	Missense	proximal	2	no	14.340	14.036	EPSD	TCGA;COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P07101	TH	P28482	MAPK1	S118	A111T	111	Missense	distal	-7	no	14.340	14.325	EPSD	TCGA	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P07101	TH	P28482	MAPK1	S502	I497M	497	Missense	distal	-5	no	14.862	14.805	EPSD	TCGA;COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P07101	TH	P28482	MAPK1	S502	R508H	508	Missense	distal	6	no	14.862	14.663	EPSD	TCGA	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P07101	TH	P28482	MAPK1	S502	R508S	508	Missense	distal	6	no	14.862	14.969	EPSD	TCGA;COSMIC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P07101	TH	P28482	MAPK1	S502	D498N	498	Missense	distal	-4	no	14.862	14.834	EPSD	TCGA;COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P15336	ATF2	P28482	MAPK1	T69	P70S	70	Missense	proximal	1	no	13.621	4.226	EPSD	TCGA;COSMIC	8.102	Loss
CMGC_MAPK_ERK1_MAPK1_ST	P15336	ATF2	P28482	MAPK1	T71	P70S	70	Missense	proximal	-1	no	13.125	13.082	PhosphoSitePlus	TCGA;COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P15336	ATF2	P28482	MAPK1	S90	E93Q	93	Missense	distal	3	no	15.863	15.940	EPSD	TCGA;COSMIC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P15336	ATF2	P28482	MAPK1	S90	G83D	83	Missense	distal	-7	no	15.863	15.878	EPSD	TCGA;COSMIC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P15336	ATF2	P28482	MAPK1	S112	T116A	116	Missense	distal	4	no	14.019	14.039	EPSD	TCGA;COSMIC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P15336	ATF2	P28482	MAPK1	S112	S112P	112	Missense	central	0	yes	14.019	0.000	EPSD	TCGA;COSMIC	8.102	Loss
CMGC_MAPK_ERK1_MAPK1_ST	P15336	ATF2	P28482	MAPK1	T116	T116A	116	Missense	central	0	yes	14.471	0.000	EPSD	TCGA;COSMIC	8.102	Loss
CMGC_MAPK_ERK1_MAPK1_ST	P15336	ATF2	P28482	MAPK1	T116	S112P	112	Missense	distal	-4	no	14.471	14.555	EPSD	TCGA;COSMIC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P15336	ATF2	P28482	MAPK1	S136	D135N	135	Missense	proximal	-1	no	14.697	14.758	EPSD	TCGA	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P15336	ATF2	P28482	MAPK1	S136	S136N	136	Missense	central	0	yes	14.697	0.000	EPSD	TCGA	8.102	Loss
CMGC_MAPK_ERK1_MAPK1_ST	P15336	ATF2	P28482	MAPK1	S266	G260E	260	Missense	distal	-6	no	16.425	16.479	EPSD	TCGA;COSMIC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P15336	ATF2	P28482	MAPK1	S266	P267S	267	Missense	proximal	1	no	16.425	7.030	EPSD	TCGA;COSMIC	8.102	Loss
CMGC_MAPK_ERK1_MAPK1_ST	P15336	ATF2	P28482	MAPK1	S266	G263C	263	Missense	distal	-3	no	16.425	15.910	EPSD	TCGA;COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P15336	ATF2	P28482	MAPK1	S314	P312L	312	Missense	proximal	-2	no	8.196	6.279	EPSD	TCGA;COSMIC	8.102	Loss
CMGC_MAPK_ERK1_MAPK1_ST	P15336	ATF2	P28482	MAPK1	S314	S321F	321	Missense	distal	7	no	8.196	8.544	EPSD	TCGA;COSMIC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P15336	ATF2	P28482	MAPK1	S314	E308Q	308	Missense	distal	-6	no	8.196	8.170	EPSD	TCGA;COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P15336	ATF2	P28482	MAPK1	S314	S310F	310	Missense	distal	-4	no	8.196	7.935	EPSD	TCGA;COSMIC	8.102	Loss
CMGC_MAPK_ERK1_MAPK1_ST	P15336	ATF2	P28482	MAPK1	T320	S321F	321	Missense	proximal	1	no	8.431	11.257	EPSD	TCGA;COSMIC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P15336	ATF2	P28482	MAPK1	T325	P326S	326	Missense	proximal	1	no	13.109	3.714	EPSD	TCGA;COSMIC	8.102	Loss
CMGC_MAPK_ERK1_MAPK1_ST	P15336	ATF2	P28482	MAPK1	T325	S321F	321	Missense	distal	-4	no	13.109	12.848	EPSD	TCGA;COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P15336	ATF2	P28482	MAPK1	S328	P326S	326	Missense	proximal	-2	no	17.310	14.476	EPSD	TCGA;COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P15336	ATF2	P28482	MAPK1	S328	P334A	334	Missense	distal	6	no	17.310	17.014	EPSD	TCGA;COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P15336	ATF2	P28482	MAPK1	S328	S321F	321	Missense	distal	-7	no	17.310	17.290	EPSD	TCGA;COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P15336	ATF2	P28482	MAPK1	T333	P326S	326	Missense	distal	-7	no	14.496	14.492	EPSD	TCGA;COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P15336	ATF2	P28482	MAPK1	T333	P334A	334	Missense	proximal	1	no	14.496	6.866	EPSD	TCGA;COSMIC	8.102	Loss
CMGC_MAPK_ERK1_MAPK1_ST	P15336	ATF2	P28482	MAPK1	T333	T339A	339	Missense	distal	6	no	14.496	14.410	EPSD	TCGA;COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P15336	ATF2	P28482	MAPK1	S446	Q453H	453	Missense	distal	7	no	17.002	17.106	EPSD	TCGA;COSMIC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P15336	ATF2	P28482	MAPK1	T449	S456L	456	Missense	distal	7	no	8.252	8.540	EPSD	TCGA;COSMIC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P15336	ATF2	P28482	MAPK1	T449	Q453H	453	Missense	distal	4	no	8.252	8.185	EPSD	TCGA;COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P15336	ATF2	P28482	MAPK1	S498	S500L	500	Missense	proximal	2	no	9.490	9.370	EPSD	TCGA;COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P15336	ATF2	P28482	MAPK1	S498	Q499L	499	Missense	proximal	1	no	9.490	9.174	EPSD	TCGA;COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P15336	ATF2	P28482	MAPK1	S498	P502L	502	Missense	distal	4	no	9.490	9.369	EPSD	TCGA;COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P15336	ATF2	P28482	MAPK1	S498	P502T	502	Missense	distal	4	no	9.490	9.366	EPSD	TCGA;COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P15336	ATF2	P28482	MAPK1	S500	S500L	500	Missense	central	0	yes	8.284	0.000	EPSD	TCGA;COSMIC	8.102	Loss
CMGC_MAPK_ERK1_MAPK1_ST	P15336	ATF2	P28482	MAPK1	S500	Q499L	499	Missense	proximal	-1	no	8.284	8.265	EPSD	TCGA;COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P15336	ATF2	P28482	MAPK1	S500	P502L	502	Missense	proximal	2	no	8.284	8.136	EPSD	TCGA;COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P15336	ATF2	P28482	MAPK1	S500	P502T	502	Missense	proximal	2	no	8.284	8.233	EPSD	TCGA;COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P23443	RPS6KB1	P28482	MAPK1	T252	H251Y	251	Missense	proximal	-1	no	9.245	9.213	EPSD	TCGA;COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P23443	RPS6KB1	P28482	MAPK1	T390	Q389E	389	Missense	proximal	-1	no	15.492	15.518	EPSD	TCGA;COSMIC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P23443	RPS6KB1	P28482	MAPK1	S394	Q389E	389	Missense	distal	-5	no	15.731	15.631	EPSD	TCGA;COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P23443	RPS6KB1	P28482	MAPK1	S503	K507R	507	Missense	distal	4	no	10.561	10.551	EPSD	TCGA;COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q92934	BAD	P28482	MAPK1	S15	E19D	19	Missense	distal	4	no	8.480	8.410	EPSD	TCGA;ICGC;COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q92934	BAD	P28482	MAPK1	S17	E19D	19	Missense	proximal	2	no	8.971	9.023	EPSD	TCGA;ICGC;COSMIC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q92934	BAD	P28482	MAPK1	S25	E19D	19	Missense	distal	-6	no	16.358	16.370	EPSD	TCGA;ICGC;COSMIC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q92934	BAD	P28482	MAPK1	S25	S25N	25	Missense	central	0	yes	16.358	0.000	EPSD	TCGA	8.102	Loss
CMGC_MAPK_ERK1_MAPK1_ST	Q92934	BAD	P28482	MAPK1	S57	G62E	62	Missense	distal	5	no	8.424	8.399	EPSD	TCGA;ICGC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q92934	BAD	P28482	MAPK1	S75	S71I	71	Missense	distal	-4	no	9.338	8.751	PhosphoSitePlus	TCGA;ICGC;COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q92934	BAD	P28482	MAPK1	S124	M117I	117	Missense	distal	-7	no	8.838	8.828	EPSD	TCGA;ICGC;COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q92934	BAD	P28482	MAPK1	S124	R131H	131	Missense	distal	7	no	8.838	9.057	EPSD	TCGA;ICGC;COSMIC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q92934	BAD	P28482	MAPK1	S134	R131H	131	Missense	distal	-3	no	8.841	8.511	EPSD	TCGA;ICGC;COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q92934	BAD	P28482	MAPK1	S134	G136D	136	Missense	proximal	2	no	8.841	8.806	EPSD	TCGA;ICGC;COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q92934	BAD	P28482	MAPK1	S134	S134I	134	Missense	central	0	yes	8.841	0.000	EPSD	TCGA	8.102	Loss
CMGC_MAPK_ERK1_MAPK1_ST	Q92934	BAD	P28482	MAPK1	S163	S164F	164	Missense	proximal	1	no	6.079	8.904	EPSD	TCGA;ICGC;COSMIC;GDSC;CCLE	8.102	Gain
CMGC_MAPK_ERK1_MAPK1_ST	Q9GZM8	NDEL1	P28482	MAPK1	S198	L201V	201	Missense	distal	3	no	15.698	15.666	EPSD	TCGA;ICGC;COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q9GZM8	NDEL1	P28482	MAPK1	S198	S194L	194	Missense	distal	-4	no	15.698	15.478	EPSD	TCGA;ICGC;COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q9GZM8	NDEL1	P28482	MAPK1	S198	A195T	195	Missense	distal	-3	no	15.698	15.856	EPSD	TCGA;ICGC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q9GZM8	NDEL1	P28482	MAPK1	S242	S247F	247	Missense	distal	5	no	13.403	13.206	EPSD	TCGA;ICGC;COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q9GZM8	NDEL1	P28482	MAPK1	T245	S247F	247	Missense	proximal	2	no	14.863	14.732	PhosphoSitePlus;EPSD	TCGA;ICGC;COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q9GZM8	NDEL1	P28482	MAPK1	S331	P325A	325	Missense	distal	-6	no	9.062	9.022	EPSD	TCGA;ICGC;COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q07343	PDE4B	P28482	MAPK1	S106	R105G	105	Missense	proximal	-1	no	12.998	12.963	EPSD	TCGA;COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q07343	PDE4B	P28482	MAPK1	S106	P110T	110	Missense	distal	4	no	12.998	12.874	EPSD	TCGA;COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q07343	PDE4B	P28482	MAPK1	S106	S102F	102	Missense	distal	-4	no	12.998	12.737	EPSD	TCGA;COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q07343	PDE4B	P28482	MAPK1	S106	P103L	103	Missense	distal	-3	no	12.998	12.614	EPSD	TCGA;COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q07343	PDE4B	P28482	MAPK1	S106	P101H	101	Missense	distal	-5	no	12.998	13.123	EPSD	TCGA;COSMIC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q07343	PDE4B	P28482	MAPK1	S106	R105W	105	Missense	proximal	-1	no	12.998	12.896	EPSD	TCGA;COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q07343	PDE4B	P28482	MAPK1	S115	L120I	120	Missense	distal	5	no	8.165	8.079	EPSD	TCGA;ICGC;COSMIC;CCLE	8.102	Loss
CMGC_MAPK_ERK1_MAPK1_ST	Q07343	PDE4B	P28482	MAPK1	S115	P110T	110	Missense	distal	-5	no	8.165	8.267	EPSD	TCGA;COSMIC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q07343	PDE4B	P28482	MAPK1	S145	S150L	150	Missense	distal	5	no	12.524	12.293	EPSD	TCGA;COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q07343	PDE4B	P28482	MAPK1	S145	D141V	141	Missense	distal	-4	no	12.524	12.184	EPSD	TCGA;COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q07343	PDE4B	P28482	MAPK1	S145	D141Y	141	Missense	distal	-4	no	12.524	11.866	EPSD	TCGA;COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q07343	PDE4B	P28482	MAPK1	S145	P146S	146	Missense	proximal	1	no	12.524	3.129	EPSD	TCGA;COSMIC	8.102	Loss
CMGC_MAPK_ERK1_MAPK1_ST	Q07343	PDE4B	P28482	MAPK1	S145	D141N	141	Missense	distal	-4	no	12.524	12.496	EPSD	TCGA;COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q07343	PDE4B	P28482	MAPK1	S145	D143N	143	Missense	proximal	-2	no	12.524	13.006	EPSD	TCGA;COSMIC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q07343	PDE4B	P28482	MAPK1	T167	G161S	161	Missense	distal	-6	no	14.341	14.358	EPSD	TCGA;COSMIC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q07343	PDE4B	P28482	MAPK1	T167	F169V	169	Missense	proximal	2	no	14.341	14.447	EPSD	TCGA;COSMIC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q07343	PDE4B	P28482	MAPK1	T167	A170V	170	Missense	distal	3	no	14.341	14.320	EPSD	TCGA;COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q07343	PDE4B	P28482	MAPK1	T167	Q171H	171	Missense	distal	4	no	14.341	14.274	EPSD	TCGA;COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q07343	PDE4B	P28482	MAPK1	S197	K195N	195	Missense	proximal	-2	no	14.069	13.669	EPSD	TCGA;COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q07343	PDE4B	P28482	MAPK1	S601	R594W	594	Missense	distal	-7	no	11.994	11.943	EPSD	TCGA;COSMIC;GDSC;CCLE	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q07343	PDE4B	P28482	MAPK1	S732	E729K	729	Missense	distal	-3	no	14.019	13.941	EPSD	TCGA;COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q9H8Y8	GORASP2	P28482	MAPK1	S26	V22A	22	Missense	distal	-4	no	15.241	15.302	EPSD	TCGA;ICGC;COSMIC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q9H8Y8	GORASP2	P28482	MAPK1	S26	G28E	28	Missense	proximal	2	no	15.241	15.155	EPSD	TCGA;ICGC;COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q9H8Y8	GORASP2	P28482	MAPK1	S26	S26F	26	Missense	central	0	yes	15.241	0.000	EPSD	TCGA;ICGC;COSMIC	8.102	Loss
CMGC_MAPK_ERK1_MAPK1_ST	Q9H8Y8	GORASP2	P28482	MAPK1	S245	N240I	240	Missense	distal	-5	no	13.653	13.836	EPSD	TCGA;ICGC;COSMIC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q9H8Y8	GORASP2	P28482	MAPK1	T264	S260Y	260	Missense	distal	-4	no	13.852	13.263	EPSD	TCGA;ICGC;COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q9H8Y8	GORASP2	P28482	MAPK1	T418	V425I	425	Missense	distal	7	no	8.875	9.140	EPSD	TCGA;ICGC;COSMIC;GDSC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P19793	RXRA	P28482	MAPK1	S21	S27C	27	Missense	distal	6	no	16.365	15.498	EPSD	TCGA;ICGC;COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P19793	RXRA	P28482	MAPK1	S21	Q14K	14	Missense	distal	-7	no	16.365	16.360	EPSD	TCGA;ICGC;COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P19793	RXRA	P28482	MAPK1	S21	Q14L	14	Missense	distal	-7	no	16.365	16.350	EPSD	TCGA;ICGC;COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P19793	RXRA	P28482	MAPK1	S49	L47V	47	Missense	proximal	-2	no	14.718	14.763	EPSD	TCGA;ICGC;COSMIC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P19793	RXRA	P28482	MAPK1	S49	S43F	43	Missense	distal	-6	no	14.718	14.634	EPSD	TCGA;ICGC;COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P19793	RXRA	P28482	MAPK1	S66	V67F	67	Missense	proximal	1	no	8.522	11.493	EPSD	TCGA;ICGC;COSMIC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P19793	RXRA	P28482	MAPK1	S66	N59S	59	Missense	distal	-7	no	8.522	8.520	EPSD	TCGA;ICGC;COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P19793	RXRA	P28482	MAPK1	S66	P63L	63	Missense	distal	-3	no	8.522	8.139	EPSD	TCGA;ICGC;COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P19793	RXRA	P28482	MAPK1	T82	S78L	78	Missense	distal	-4	no	16.735	16.514	EPSD	TCGA;ICGC;COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P19793	RXRA	P28482	MAPK1	T82	M77V	77	Missense	distal	-5	no	16.735	16.678	EPSD	TCGA;ICGC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P19793	RXRA	P28482	MAPK1	S225	P231L	231	Missense	distal	6	no	8.135	7.729	EPSD	TCGA;ICGC;COSMIC	8.102	Loss
CMGC_MAPK_ERK1_MAPK1_ST	P19793	RXRA	P28482	MAPK1	S225	A226T	226	Missense	proximal	1	no	8.135	7.267	EPSD	TCGA;ICGC;COSMIC;GDSC	8.102	Loss
CMGC_MAPK_ERK1_MAPK1_ST	P19793	RXRA	P28482	MAPK1	S260	V265I	265	Missense	distal	5	no	17.748	17.574	PhosphoSitePlus	TCGA	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P19793	RXRA	P28482	MAPK1	S260	G255W	255	Missense	distal	-5	no	17.748	18.004	PhosphoSitePlus	TCGA;ICGC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	O43623	SNAI2	P28482	MAPK1	S54	G51E	51	Missense	distal	-3	no	13.694	13.703	EPSD	TCGA;ICGC;COSMIC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	O43623	SNAI2	P28482	MAPK1	S54	A52E	52	Missense	proximal	-2	no	13.694	14.461	EPSD	TCGA;ICGC;COSMIC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	O43623	SNAI2	P28482	MAPK1	S104	E110K	110	Missense	distal	6	no	15.466	15.490	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	O43623	SNAI2	P28482	MAPK1	S104	E110V	110	Missense	distal	6	no	15.466	15.218	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	O43623	SNAI2	P28482	MAPK1	S104	K97M	97	Missense	distal	-7	no	15.466	15.447	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	O43623	SNAI2	P28482	MAPK1	S104	D98Y	98	Missense	distal	-6	no	15.466	15.303	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	O43623	SNAI2	P28482	MAPK1	T234	D237N	237	Missense	distal	3	no	8.283	8.188	EPSD	TCGA;ICGC;COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	O43623	SNAI2	P28482	MAPK1	T234	K239E	239	Missense	distal	5	no	8.283	8.343	EPSD	TCGA;ICGC;COSMIC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	O43623	SNAI2	P28482	MAPK1	T234	L228M	228	Missense	distal	-6	no	8.283	8.291	EPSD	TCGA;ICGC;COSMIC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	O43623	SNAI2	P28482	MAPK1	S251	T249P	249	Missense	proximal	-2	no	6.358	9.058	EPSD	TCGA;ICGC;COSMIC	8.102	Gain
CMGC_MAPK_ERK1_MAPK1_ST	O43623	SNAI2	P28482	MAPK1	S254	F250L	250	Missense	distal	-4	no	9.162	9.202	EPSD	TCGA;ICGC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	O43623	SNAI2	P28482	MAPK1	S254	E261D	261	Missense	distal	7	no	9.162	9.217	EPSD	TCGA;ICGC;COSMIC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	O43623	SNAI2	P28482	MAPK1	S254	S247F	247	Missense	distal	-7	no	9.162	9.142	EPSD	TCGA	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	O43623	SNAI2	P28482	MAPK1	S254	T249P	249	Missense	distal	-5	no	9.162	9.059	EPSD	TCGA;ICGC;COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P78536	ADAM17	P28482	MAPK1	S4	L5F	5	Missense	proximal	1	no	5.870	8.110	EPSD	TCGA;ICGC;COSMIC	8.102	Gain
CMGC_MAPK_ERK1_MAPK1_ST	P78536	ADAM17	P28482	MAPK1	S180	P181L	181	Missense	proximal	1	no	16.670	7.860	EPSD	TCGA;ICGC;COSMIC	8.102	Loss
CMGC_MAPK_ERK1_MAPK1_ST	P78536	ADAM17	P28482	MAPK1	S180	S176L	176	Missense	distal	-4	no	16.670	16.449	EPSD	TCGA;ICGC;COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P78536	ADAM17	P28482	MAPK1	S180	R177C	177	Missense	distal	-3	no	16.670	15.986	EPSD	TCGA;ICGC;COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P78536	ADAM17	P28482	MAPK1	S721	M719I	719	Missense	proximal	-2	no	6.105	8.225	EPSD	TCGA;ICGC;COSMIC	8.102	Gain
CMGC_MAPK_ERK1_MAPK1_ST	P78536	ADAM17	P28482	MAPK1	S808	R813C	813	Missense	distal	5	no	9.361	8.930	EPSD	TCGA;ICGC;COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P78536	ADAM17	P28482	MAPK1	S808	R802K	802	Missense	distal	-6	no	9.361	9.338	EPSD	TCGA;ICGC;COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P78536	ADAM17	P28482	MAPK1	S808	A806V	806	Missense	proximal	-2	no	9.361	10.635	EPSD	TCGA;ICGC;COSMIC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q8WX93	PALLD	P28482	MAPK1	S15	E8Q	8	Missense	distal	-7	no	8.108	8.106	EPSD	TCGA;ICGC;COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q8WX93	PALLD	P28482	MAPK1	S15	K22N	22	Missense	distal	7	no	8.108	8.142	EPSD	TCGA;ICGC;COSMIC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q8WX93	PALLD	P28482	MAPK1	S71	S71F	71	Missense	central	0	yes	13.470	0.000	EPSD	TCGA;ICGC;COSMIC	8.102	Loss
CMGC_MAPK_ERK1_MAPK1_ST	Q8WX93	PALLD	P28482	MAPK1	S71	P72H	72	Missense	proximal	1	no	13.470	5.646	EPSD	TCGA;COSMIC	8.102	Loss
CMGC_MAPK_ERK1_MAPK1_ST	Q8WX93	PALLD	P28482	MAPK1	T100	A106E	106	Missense	distal	6	no	14.453	14.782	EPSD	TCGA;ICGC;COSMIC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q8WX93	PALLD	P28482	MAPK1	T100	P101H	101	Missense	proximal	1	no	14.453	6.629	EPSD	TCGA;COSMIC	8.102	Loss
CMGC_MAPK_ERK1_MAPK1_ST	Q8WX93	PALLD	P28482	MAPK1	T100	Q95H	95	Missense	distal	-5	no	14.453	14.452	EPSD	TCGA;COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q8WX93	PALLD	P28482	MAPK1	S125	S132N	132	Missense	distal	7	no	12.744	12.727	EPSD	TCGA;COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q8WX93	PALLD	P28482	MAPK1	S125	P126L	126	Missense	proximal	1	no	12.744	3.935	EPSD	TCGA;COSMIC	8.102	Loss
CMGC_MAPK_ERK1_MAPK1_ST	Q8WX93	PALLD	P28482	MAPK1	S132	S136N	136	Missense	distal	4	no	8.651	8.613	EPSD	TCGA	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q8WX93	PALLD	P28482	MAPK1	S132	S132N	132	Missense	central	0	yes	8.651	0.000	EPSD	TCGA;COSMIC	8.102	Loss
CMGC_MAPK_ERK1_MAPK1_ST	Q8WX93	PALLD	P28482	MAPK1	S132	P126L	126	Missense	distal	-6	no	8.651	8.559	EPSD	TCGA;COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q8WX93	PALLD	P28482	MAPK1	T147	R143C	143	Missense	distal	-4	no	10.837	10.199	EPSD	TCGA;COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q8WX93	PALLD	P28482	MAPK1	T147	G144R	144	Missense	distal	-3	no	10.837	11.006	EPSD	TCGA;COSMIC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q8WX93	PALLD	P28482	MAPK1	T147	R143S	143	Missense	distal	-4	no	10.837	10.842	EPSD	TCGA;COSMIC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q8WX93	PALLD	P28482	MAPK1	T147	P148L	148	Missense	proximal	1	no	10.837	2.027	EPSD	TCGA;COSMIC	8.102	Loss
CMGC_MAPK_ERK1_MAPK1_ST	Q8WX93	PALLD	P28482	MAPK1	T147	S149G	149	Missense	proximal	2	no	10.837	10.883	EPSD	TCGA;COSMIC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q8WX93	PALLD	P28482	MAPK1	S192	R189T	189	Missense	distal	-3	no	10.428	10.238	EPSD	TCGA;COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q8WX93	PALLD	P28482	MAPK1	S199	S202R	202	Missense	distal	3	no	12.436	12.412	EPSD	TCGA;COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q8WX93	PALLD	P28482	MAPK1	S206	P207S	207	Missense	proximal	1	no	14.383	4.989	EPSD	TCGA;COSMIC	8.102	Loss
CMGC_MAPK_ERK1_MAPK1_ST	Q8WX93	PALLD	P28482	MAPK1	S206	S202R	202	Missense	distal	-4	no	14.383	14.378	EPSD	TCGA;COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q8WX93	PALLD	P28482	MAPK1	S222	G228E	228	Missense	distal	6	no	14.479	14.590	EPSD	TCGA;COSMIC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q8WX93	PALLD	P28482	MAPK1	S236	A239V	239	Missense	distal	3	no	14.164	14.143	EPSD	TCGA;COSMIC;GDSC;CCLE	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q8WX93	PALLD	P28482	MAPK1	S401	G398R	398	Missense	distal	-3	no	14.094	14.263	EPSD	TCGA;COSMIC;CCLE	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q8WX93	PALLD	P28482	MAPK1	S423	L428I	428	Missense	distal	5	no	13.511	13.425	EPSD	TCGA;COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q8WX93	PALLD	P28482	MAPK1	S423	R430Q	430	Missense	distal	7	no	13.511	13.626	EPSD	TCGA;COSMIC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q8WX93	PALLD	P28482	MAPK1	S484	S484F	484	Missense	central	0	yes	12.366	0.000	EPSD	TCGA;COSMIC	8.102	Loss
CMGC_MAPK_ERK1_MAPK1_ST	Q8WX93	PALLD	P28482	MAPK1	T635	L640R	640	Missense	distal	5	no	13.039	13.302	EPSD	TCGA;ICGC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q8WX93	PALLD	P28482	MAPK1	T635	A637S	637	Missense	proximal	2	no	13.039	13.141	EPSD	TCGA;ICGC;COSMIC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q8WX93	PALLD	P28482	MAPK1	S641	L640R	640	Missense	proximal	-1	no	15.205	15.245	EPSD	TCGA;ICGC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q8WX93	PALLD	P28482	MAPK1	S641	A637S	637	Missense	distal	-4	no	15.205	15.414	EPSD	TCGA;ICGC;COSMIC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q8WX93	PALLD	P28482	MAPK1	S641	P648L	648	Missense	distal	7	no	15.205	15.504	EPSD	TCGA;ICGC;COSMIC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q15797	SMAD1	P28482	MAPK1	S11	A13T	13	Missense	proximal	2	no	15.056	15.135	EPSD	TCGA;ICGC;COSMIC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q15797	SMAD1	P28482	MAPK1	S132	R129K	129	Missense	distal	-3	no	13.145	12.907	EPSD	TCGA;ICGC;COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q15797	SMAD1	P28482	MAPK1	S132	L139V	139	Missense	distal	7	no	13.145	13.140	EPSD	TCGA;ICGC;COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q15797	SMAD1	P28482	MAPK1	S187	S190T	190	Missense	distal	3	no	16.983	16.976	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q15797	SMAD1	P28482	MAPK1	S195	G197V	197	Missense	proximal	2	no	16.646	16.574	PhosphoSitePlus;EPSD	TCGA;ICGC;COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q15797	SMAD1	P28482	MAPK1	S195	S190T	190	Missense	distal	-5	no	16.646	16.675	PhosphoSitePlus;EPSD	TCGA;ICGC;COSMIC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q15797	SMAD1	P28482	MAPK1	S214	D221G	221	Missense	distal	7	no	16.360	16.432	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q15797	SMAD1	P28482	MAPK1	S462	V464L	464	Missense	proximal	2	no	9.883	9.789	EPSD	TCGA;ICGC;COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q15797	SMAD1	P28482	MAPK1	S463	V464L	464	Missense	proximal	1	no	9.283	10.014	EPSD	TCGA;ICGC;COSMIC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q13127	REST	P28482	MAPK1	S734	E732V	732	Missense	proximal	-2	no	13.489	13.996	EPSD	TCGA;ICGC;COSMIC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q13127	REST	P28482	MAPK1	S734	P736L	736	Missense	proximal	2	no	13.489	13.342	EPSD	TCGA;ICGC;COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q13127	REST	P28482	MAPK1	S750	P752L	752	Missense	proximal	2	no	13.959	13.811	EPSD	TCGA;ICGC;COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q13127	REST	P28482	MAPK1	S766	E764V	764	Missense	proximal	-2	no	13.930	14.437	EPSD	TCGA;ICGC;COSMIC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q13127	REST	P28482	MAPK1	S766	L765M	765	Missense	proximal	-1	no	13.930	13.940	EPSD	TCGA;ICGC;COSMIC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q13127	REST	P28482	MAPK1	S864	N871K	871	Missense	distal	7	no	16.895	16.861	EPSD;PhosphoSitePlus	TCGA;ICGC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q13127	REST	P28482	MAPK1	S971	L974F	974	Missense	distal	3	no	16.928	16.970	EPSD	TCGA;ICGC;COSMIC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q13127	REST	P28482	MAPK1	S971	P976L	976	Missense	distal	5	no	16.928	16.714	EPSD	TCGA;ICGC;COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q13127	REST	P28482	MAPK1	S971	T965I	965	Missense	distal	-6	no	16.928	16.850	EPSD	TCGA;ICGC;COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q04637	EIF4G1	P28482	MAPK1	S15	A22T	22	Missense	distal	7	no	16.266	16.237	EPSD	TCGA;ICGC;COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q04637	EIF4G1	P28482	MAPK1	T43	S45Y	45	Missense	proximal	2	no	12.314	12.147	EPSD	TCGA;COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q04637	EIF4G1	P28482	MAPK1	S134	G139S	139	Missense	distal	5	no	14.237	14.256	EPSD	TCGA	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q04637	EIF4G1	P28482	MAPK1	S253	S260I	260	Missense	distal	7	no	13.564	14.112	EPSD	TCGA	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q04637	EIF4G1	P28482	MAPK1	S261	S267L	267	Missense	distal	6	no	16.539	16.133	EPSD	TCGA;COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q04637	EIF4G1	P28482	MAPK1	S261	S260I	260	Missense	proximal	-1	no	16.539	16.517	EPSD	TCGA	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q04637	EIF4G1	P28482	MAPK1	S263	S267L	267	Missense	distal	4	no	14.971	14.861	EPSD	TCGA;COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q04637	EIF4G1	P28482	MAPK1	S263	S260I	260	Missense	distal	-3	no	14.971	14.706	EPSD	TCGA	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q04637	EIF4G1	P28482	MAPK1	T265	S267L	267	Missense	proximal	2	no	14.574	14.454	EPSD	TCGA;COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q04637	EIF4G1	P28482	MAPK1	T265	S260I	260	Missense	distal	-5	no	14.574	14.708	EPSD	TCGA	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q04637	EIF4G1	P28482	MAPK1	S267	S267L	267	Missense	central	0	yes	13.257	0.000	EPSD	TCGA;COSMIC	8.102	Loss
CMGC_MAPK_ERK1_MAPK1_ST	Q04637	EIF4G1	P28482	MAPK1	S267	S260I	260	Missense	distal	-7	no	13.257	13.230	EPSD	TCGA	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q04637	EIF4G1	P28482	MAPK1	S269	S267L	267	Missense	proximal	-2	no	14.135	15.052	EPSD	TCGA;COSMIC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q04637	EIF4G1	P28482	MAPK1	S1092	G1096W	1096	Missense	distal	4	no	8.122	7.865	EPSD	TCGA;COSMIC	8.102	Loss
CMGC_MAPK_ERK1_MAPK1_ST	Q04637	EIF4G1	P28482	MAPK1	T1179	R1173Q	1173	Missense	distal	-6	no	14.265	14.241	EPSD	TCGA	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q13586	STIM1	P28482	MAPK1	S492	S492P	492	Missense	central	0	yes	13.552	0.000	EPSD	TCGA;COSMIC	8.102	Loss
CMGC_MAPK_ERK1_MAPK1_ST	Q13586	STIM1	P28482	MAPK1	S600	A593T	593	Missense	distal	-7	no	14.780	14.766	EPSD	TCGA;COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q13586	STIM1	P28482	MAPK1	S668	G670D	670	Missense	proximal	2	no	16.481	16.447	EPSD	TCGA;COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q13586	STIM1	P28482	MAPK1	S668	D666Y	666	Missense	proximal	-2	no	16.481	17.665	EPSD	TCGA	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q02224	CENPE	P28482	MAPK1	S130	E137K	137	Missense	distal	7	no	8.500	8.508	EPSD	TCGA;ICGC;COSMIC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q02224	CENPE	P28482	MAPK1	S130	V129L	129	Missense	proximal	-1	no	8.500	8.466	EPSD	TCGA;ICGC;COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q02224	CENPE	P28482	MAPK1	S130	R128C	128	Missense	proximal	-2	no	8.500	6.552	EPSD	TCGA;ICGC;COSMIC	8.102	Loss
CMGC_MAPK_ERK1_MAPK1_ST	Q02224	CENPE	P28482	MAPK1	S130	L126I	126	Missense	distal	-4	no	8.500	8.134	EPSD	TCGA;ICGC;COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q02224	CENPE	P28482	MAPK1	S312	S312F	312	Missense	central	0	yes	9.305	0.000	EPSD	TCGA;ICGC;COSMIC	8.102	Loss
CMGC_MAPK_ERK1_MAPK1_ST	Q02224	CENPE	P28482	MAPK1	S312	I305V	305	Missense	distal	-7	no	9.305	9.318	EPSD	TCGA;ICGC;COSMIC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q02224	CENPE	P28482	MAPK1	S2605	S2605Y	2605	Missense	central	0	yes	14.093	0.000	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	8.102	Loss
CMGC_MAPK_ERK1_MAPK1_ST	Q02224	CENPE	P28482	MAPK1	S2608	S2605Y	2605	Missense	distal	-3	no	15.650	15.381	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q02224	CENPE	P28482	MAPK1	S2639	P2634S	2634	Missense	distal	-5	no	15.002	15.076	PhosphoSitePlus;EPSD	TCGA;ICGC;COSMIC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q02224	CENPE	P28482	MAPK1	S2639	E2638Q	2638	Missense	proximal	-1	no	15.002	14.976	PhosphoSitePlus;EPSD	TCGA;ICGC;COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q02224	CENPE	P28482	MAPK1	S2639	P2634H	2634	Missense	distal	-5	no	15.002	15.127	PhosphoSitePlus;EPSD	TCGA;ICGC;COSMIC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q02224	CENPE	P28482	MAPK1	S2639	S2642Y	2642	Missense	distal	3	no	15.002	15.060	PhosphoSitePlus;EPSD	TCGA;ICGC;COSMIC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q02224	CENPE	P28482	MAPK1	S2639	P2636S	2636	Missense	distal	-3	no	15.002	14.825	PhosphoSitePlus;EPSD	TCGA;ICGC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q02224	CENPE	P28482	MAPK1	S2654	S2651Y	2651	Missense	distal	-3	no	13.737	13.468	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q02224	CENPE	P28482	MAPK1	S2654	S2651C	2651	Missense	distal	-3	no	13.737	13.211	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q02224	CENPE	P28482	MAPK1	S2654	R2659L	2659	Missense	distal	5	no	13.737	13.475	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q02224	CENPE	P28482	MAPK1	S2654	R2659C	2659	Missense	distal	5	no	13.737	13.306	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC;GDSC;CCLE	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P50616	TOB1	P28482	MAPK1	S143	S147L	147	Missense	distal	4	no	9.563	9.453	EPSD	TCGA;ICGC;COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P50616	TOB1	P28482	MAPK1	S143	I142T	142	Missense	proximal	-1	no	9.563	9.587	EPSD	TCGA;ICGC;COSMIC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P50616	TOB1	P28482	MAPK1	S147	S147L	147	Missense	central	0	yes	8.397	0.000	EPSD	TCGA;ICGC;COSMIC	8.102	Loss
CMGC_MAPK_ERK1_MAPK1_ST	P50616	TOB1	P28482	MAPK1	S147	I142T	142	Missense	distal	-5	no	8.397	8.291	EPSD	TCGA;ICGC;COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P50616	TOB1	P28482	MAPK1	S152	S147L	147	Missense	distal	-5	no	13.582	13.657	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P50616	TOB1	P28482	MAPK1	S154	S147L	147	Missense	distal	-7	no	15.193	15.185	PhosphoSitePlus;EPSD	TCGA;ICGC;COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P50616	TOB1	P28482	MAPK1	S164	S164N	164	Missense	central	0	yes	14.103	0.000	EPSD;PhosphoSitePlus	TCGA	8.102	Loss
CMGC_MAPK_ERK1_MAPK1_ST	P50616	TOB1	P28482	MAPK1	S164	M168V	168	Missense	distal	4	no	14.103	14.191	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P50616	TOB1	P28482	MAPK1	S205	S205F	205	Missense	central	0	yes	14.727	0.000	EPSD	TCGA;ICGC;COSMIC	8.102	Loss
CMGC_MAPK_ERK1_MAPK1_ST	P50616	TOB1	P28482	MAPK1	S205	N208S	208	Missense	distal	3	no	14.727	14.805	EPSD	TCGA;ICGC;COSMIC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P50616	TOB1	P28482	MAPK1	S205	G210R	210	Missense	distal	5	no	14.727	14.777	EPSD	TCGA;ICGC;COSMIC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P50616	TOB1	P28482	MAPK1	S205	L209F	209	Missense	distal	4	no	14.727	14.659	EPSD	TCGA;ICGC;COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P50616	TOB1	P28482	MAPK1	S205	V201A	201	Missense	distal	-4	no	14.727	14.787	EPSD	TCGA;ICGC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P50616	TOB1	P28482	MAPK1	S205	R203H	203	Missense	proximal	-2	no	14.727	13.790	EPSD	TCGA;ICGC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P50616	TOB1	P28482	MAPK1	S205	K200N	200	Missense	distal	-5	no	14.727	14.750	EPSD	TCGA;ICGC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P50616	TOB1	P28482	MAPK1	S268	S265T	265	Missense	distal	-3	no	14.102	14.069	EPSD	TCGA;ICGC;COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P49815	TSC2	P28482	MAPK1	T23	S30Y	30	Missense	distal	7	no	16.713	17.231	EPSD	TCGA;ICGC;COSMIC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P49815	TSC2	P28482	MAPK1	S30	E32Q	32	Missense	proximal	2	no	10.401	10.291	EPSD	TCGA;ICGC;COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P49815	TSC2	P28482	MAPK1	S30	S30Y	30	Missense	central	0	yes	10.401	0.000	EPSD	TCGA;ICGC;COSMIC	8.102	Loss
CMGC_MAPK_ERK1_MAPK1_ST	P49815	TSC2	P28482	MAPK1	S540	R537H	537	Missense	distal	-3	no	13.757	13.428	EPSD	TCGA;ICGC;COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P49815	TSC2	P28482	MAPK1	S664	K657R	657	Missense	distal	-7	no	17.995	17.991	PhosphoSitePlus	TCGA;ICGC;COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P49815	TSC2	P28482	MAPK1	S664	G668W	668	Missense	distal	4	no	17.995	17.738	PhosphoSitePlus	TCGA;ICGC;COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P49815	TSC2	P28482	MAPK1	T667	G668W	668	Missense	proximal	1	no	6.229	8.918	EPSD	TCGA;ICGC;COSMIC	8.102	Gain
CMGC_MAPK_ERK1_MAPK1_ST	P49815	TSC2	P28482	MAPK1	S923	R917L	917	Missense	distal	-6	no	8.522	8.422	EPSD	TCGA	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P49815	TSC2	P28482	MAPK1	S923	R917W	917	Missense	distal	-6	no	8.522	8.302	EPSD	TCGA;ICGC;COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P49815	TSC2	P28482	MAPK1	S923	R917Q	917	Missense	distal	-6	no	8.522	8.498	EPSD	TCGA	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P49815	TSC2	P28482	MAPK1	T927	R934S	934	Missense	distal	7	no	13.942	13.939	EPSD	TCGA;ICGC;COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P49815	TSC2	P28482	MAPK1	S932	R934S	934	Missense	proximal	2	no	9.149	9.008	EPSD	TCGA;ICGC;COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P49815	TSC2	P28482	MAPK1	S946	R943K	943	Missense	distal	-3	no	8.996	8.758	EPSD	TCGA;ICGC;COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P49815	TSC2	P28482	MAPK1	S1002	D1004N	1004	Missense	proximal	2	no	8.547	8.486	EPSD	TCGA;COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P49815	TSC2	P28482	MAPK1	S1002	G1001V	1001	Missense	proximal	-1	no	8.547	8.575	EPSD	TCGA;COSMIC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P49815	TSC2	P28482	MAPK1	S1045	L1051I	1051	Missense	distal	6	no	14.811	14.551	EPSD	TCGA	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P49815	TSC2	P28482	MAPK1	S1045	E1049K	1049	Missense	distal	4	no	14.811	14.825	EPSD	TCGA;COSMIC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P49815	TSC2	P28482	MAPK1	S1045	S1045F	1045	Missense	central	0	yes	14.811	0.000	EPSD	TCGA	8.102	Loss
CMGC_MAPK_ERK1_MAPK1_ST	P49815	TSC2	P28482	MAPK1	S1045	S1045Y	1045	Missense	central	0	yes	14.811	0.000	EPSD	TCGA;COSMIC	8.102	Loss
CMGC_MAPK_ERK1_MAPK1_ST	P49815	TSC2	P28482	MAPK1	S1097	P1098L	1098	Missense	proximal	1	no	13.925	5.115	EPSD	TCGA;COSMIC	8.102	Loss
CMGC_MAPK_ERK1_MAPK1_ST	P49815	TSC2	P28482	MAPK1	S1097	G1091S	1091	Missense	distal	-6	no	13.925	13.942	EPSD	TCGA;COSMIC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P49815	TSC2	P28482	MAPK1	S1274	R1268C	1268	Missense	distal	-6	no	9.069	8.894	EPSD	TCGA;COSMIC;CCLE	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P49815	TSC2	P28482	MAPK1	S1388	S1386I	1386	Missense	proximal	-2	no	13.389	14.329	EPSD	TCGA;COSMIC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P49815	TSC2	P28482	MAPK1	S1449	S1449C	1449	Missense	central	0	yes	14.976	0.000	EPSD	TCGA;COSMIC	8.102	Loss
CMGC_MAPK_ERK1_MAPK1_ST	P49815	TSC2	P28482	MAPK1	S1449	R1451C	1451	Missense	proximal	2	no	14.976	14.603	EPSD	TCGA;COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P49815	TSC2	P28482	MAPK1	S1452	S1449C	1449	Missense	distal	-3	no	18.155	17.628	EPSD	TCGA;COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P49815	TSC2	P28482	MAPK1	S1452	R1457Q	1457	Missense	distal	5	no	18.155	17.985	EPSD	TCGA;COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P49815	TSC2	P28482	MAPK1	S1452	R1451C	1451	Missense	proximal	-1	no	18.155	18.053	EPSD	TCGA;COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P49815	TSC2	P28482	MAPK1	S1539	D1541N	1541	Missense	proximal	2	no	8.466	8.406	EPSD	TCGA;COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P10415	BCL2	P28482	MAPK1	T56	A61T	61	Missense	distal	5	no	14.539	14.625	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC;CCLE	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q9NQ66	PLCB1	P28482	MAPK1	T39	R44S	44	Missense	distal	5	no	15.441	15.409	EPSD	TCGA;ICGC;COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q9NQ66	PLCB1	P28482	MAPK1	T39	D33N	33	Missense	distal	-6	no	15.441	15.395	EPSD	TCGA;ICGC;COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q9NQ66	PLCB1	P28482	MAPK1	S387	A394S	394	Missense	distal	7	no	8.431	8.250	EPSD	TCGA;ICGC;COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q9NQ66	PLCB1	P28482	MAPK1	S387	T383A	383	Missense	distal	-4	no	8.431	8.452	EPSD	TCGA;ICGC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q9NQ66	PLCB1	P28482	MAPK1	S410	S410L	410	Missense	central	0	yes	9.459	0.000	EPSD	TCGA;ICGC;COSMIC;GDSC;CCLE	8.102	Loss
CMGC_MAPK_ERK1_MAPK1_ST	Q9NQ66	PLCB1	P28482	MAPK1	S410	S417F	417	Missense	distal	7	no	9.459	9.806	EPSD	TCGA;ICGC;COSMIC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q9NQ66	PLCB1	P28482	MAPK1	S410	E412A	412	Missense	proximal	2	no	9.459	9.396	EPSD	TCGA;ICGC;COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q9NQ66	PLCB1	P28482	MAPK1	S410	P406L	406	Missense	distal	-4	no	9.459	9.154	EPSD	TCGA;ICGC;COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q9NQ66	PLCB1	P28482	MAPK1	S410	V415M	415	Missense	distal	5	no	9.459	9.397	EPSD	TCGA;ICGC;COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q9NQ66	PLCB1	P28482	MAPK1	S417	S410L	410	Missense	distal	-7	no	16.300	16.292	EPSD	TCGA;ICGC;COSMIC;GDSC;CCLE	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q9NQ66	PLCB1	P28482	MAPK1	S417	S417F	417	Missense	central	0	yes	16.300	0.000	EPSD	TCGA;ICGC;COSMIC	8.102	Loss
CMGC_MAPK_ERK1_MAPK1_ST	Q9NQ66	PLCB1	P28482	MAPK1	S417	E412A	412	Missense	distal	-5	no	16.300	16.399	EPSD	TCGA;ICGC;COSMIC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q9NQ66	PLCB1	P28482	MAPK1	S417	V415M	415	Missense	proximal	-2	no	16.300	14.158	EPSD	TCGA;ICGC;COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q9NQ66	PLCB1	P28482	MAPK1	S454	P455L	455	Missense	proximal	1	no	11.664	2.854	EPSD	TCGA;ICGC;COSMIC	8.102	Loss
CMGC_MAPK_ERK1_MAPK1_ST	Q9NQ66	PLCB1	P28482	MAPK1	S454	S454R	454	Missense	central	0	yes	11.664	0.000	EPSD	TCGA;ICGC;COSMIC	8.102	Loss
CMGC_MAPK_ERK1_MAPK1_ST	Q9NQ66	PLCB1	P28482	MAPK1	S454	D457N	457	Missense	distal	3	no	11.664	11.568	EPSD	TCGA;ICGC;COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q9NQ66	PLCB1	P28482	MAPK1	S501	G505A	505	Missense	distal	4	no	17.571	17.527	EPSD	TCGA;COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q9NQ66	PLCB1	P28482	MAPK1	S501	S495R	495	Missense	distal	-6	no	17.571	17.605	EPSD	TCGA;ICGC;COSMIC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q9NQ66	PLCB1	P28482	MAPK1	S501	S501Y	501	Missense	central	0	yes	17.571	0.000	EPSD	TCGA;ICGC;COSMIC	8.102	Loss
CMGC_MAPK_ERK1_MAPK1_ST	Q9NQ66	PLCB1	P28482	MAPK1	S501	M496I	496	Missense	distal	-5	no	17.571	17.627	EPSD	TCGA;ICGC;COSMIC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q9NQ66	PLCB1	P28482	MAPK1	S501	E498K	498	Missense	distal	-3	no	17.571	17.493	EPSD	TCGA;ICGC;COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q9NQ66	PLCB1	P28482	MAPK1	S582	V584M	584	Missense	proximal	2	no	13.843	13.706	EPSD	TCGA;ICGC;COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q9NQ66	PLCB1	P28482	MAPK1	S582	F586Y	586	Missense	distal	4	no	13.843	13.826	EPSD	TCGA;ICGC;COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q9NQ66	PLCB1	P28482	MAPK1	T871	H866N	866	Missense	distal	-5	no	13.510	13.411	EPSD	TCGA;ICGC;COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q9NQ66	PLCB1	P28482	MAPK1	T871	V864L	864	Missense	distal	-7	no	13.510	13.517	EPSD	TCGA;ICGC;COSMIC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q9NQ66	PLCB1	P28482	MAPK1	T871	H866Y	866	Missense	distal	-5	no	13.510	13.591	EPSD	TCGA;ICGC;COSMIC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q9NQ66	PLCB1	P28482	MAPK1	S982	T989M	989	Missense	distal	7	no	16.923	17.131	PhosphoSitePlus	TCGA;ICGC;COSMIC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q9NQ66	PLCB1	P28482	MAPK1	S982	G986C	986	Missense	distal	4	no	16.923	16.691	PhosphoSitePlus	TCGA;ICGC;COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q9NQ66	PLCB1	P28482	MAPK1	S982	P983H	983	Missense	proximal	1	no	16.923	9.100	PhosphoSitePlus	TCGA;ICGC;COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q9NQ66	PLCB1	P28482	MAPK1	S982	H985Y	985	Missense	distal	3	no	16.923	16.962	PhosphoSitePlus	TCGA;ICGC;COSMIC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q9NQ66	PLCB1	P28482	MAPK1	S982	S981N	981	Missense	proximal	-1	no	16.923	16.972	PhosphoSitePlus	TCGA;ICGC;COSMIC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q9NQ66	PLCB1	P28482	MAPK1	T1197	V1193G	1193	Missense	distal	-4	no	16.585	16.589	EPSD	TCGA;ICGC;COSMIC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q9NQ66	PLCB1	P28482	MAPK1	T1197	G1191V	1191	Missense	distal	-6	no	16.585	16.542	EPSD	TCGA;ICGC;COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q9NQ66	PLCB1	P28482	MAPK1	T1197	P1190T	1190	Missense	distal	-7	no	16.585	16.568	EPSD	TCGA;ICGC;COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q9NQ66	PLCB1	P28482	MAPK1	T1197	P1190H	1190	Missense	distal	-7	no	16.585	16.569	EPSD	TCGA;ICGC;COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q9NQ66	PLCB1	P28482	MAPK1	S1199	V1193G	1193	Missense	distal	-6	no	8.231	8.274	EPSD	TCGA;ICGC;COSMIC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q9NQ66	PLCB1	P28482	MAPK1	S1200	I1207V	1207	Missense	distal	7	no	10.684	10.419	EPSD	TCGA;ICGC;COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P17655	CAPN2	P28482	MAPK1	S50	P49T	49	Missense	proximal	-1	no	8.446	8.404	PhosphoSitePlus	TCGA;ICGC;COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P17655	CAPN2	P28482	MAPK1	S50	A57T	57	Missense	distal	7	no	8.446	8.417	PhosphoSitePlus	TCGA;ICGC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P17655	CAPN2	P28482	MAPK1	S67	T70A	70	Missense	distal	3	no	8.354	8.370	EPSD	TCGA;ICGC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P17655	CAPN2	P28482	MAPK1	S277	E270K	270	Missense	distal	-7	no	8.508	8.501	EPSD	TCGA;ICGC;COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P17655	CAPN2	P28482	MAPK1	T380	N384S	384	Missense	distal	4	no	11.058	11.096	EPSD	TCGA;ICGC;COSMIC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P17655	CAPN2	P28482	MAPK1	T380	G373R	373	Missense	distal	-7	no	11.058	11.071	EPSD	TCGA	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P17655	CAPN2	P28482	MAPK1	T380	R375S	375	Missense	distal	-5	no	11.058	11.085	EPSD	TCGA;ICGC;COSMIC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P17655	CAPN2	P28482	MAPK1	T464	R459M	459	Missense	distal	-5	no	8.285	8.390	EPSD	TCGA;ICGC;COSMIC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P17655	CAPN2	P28482	MAPK1	T464	V471A	471	Missense	distal	7	no	8.285	8.183	EPSD	TCGA;ICGC;COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P30041	PRDX6	P28482	MAPK1	T44	S38F	38	Missense	distal	-6	no	13.824	13.739	EPSD	TCGA;ICGC;COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P30041	PRDX6	P28482	MAPK1	S75	V76A	76	Missense	proximal	1	no	6.516	8.426	EPSD	TCGA;ICGC	8.102	Gain
CMGC_MAPK_ERK1_MAPK1_ST	P30041	PRDX6	P28482	MAPK1	T177	D180H	180	Missense	distal	3	no	13.903	13.906	PhosphoSitePlus	TCGA;ICGC;COSMIC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P30041	PRDX6	P28482	MAPK1	T177	R174K	174	Missense	distal	-3	no	13.903	13.665	PhosphoSitePlus	TCGA;ICGC;COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P30041	PRDX6	P28482	MAPK1	T177	R174M	174	Missense	distal	-3	no	13.903	13.486	PhosphoSitePlus	TCGA;ICGC;COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q9BY84	DUSP16	P28482	MAPK1	S446	S452L	452	Missense	distal	6	no	13.637	13.230	PhosphoSitePlus	TCGA;ICGC;COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q9BY84	DUSP16	P28482	MAPK1	T455	S452L	452	Missense	distal	-3	no	12.382	12.175	EPSD	TCGA;ICGC;COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q9BY84	DUSP16	P28482	MAPK1	T455	S452P	452	Missense	distal	-3	no	12.382	12.559	EPSD	TCGA;ICGC;COSMIC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q9BY84	DUSP16	P28482	MAPK1	S459	E457K	457	Missense	proximal	-2	no	14.430	14.390	EPSD	TCGA;ICGC;COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q9BY84	DUSP16	P28482	MAPK1	S459	S452L	452	Missense	distal	-7	no	14.430	14.422	EPSD	TCGA;ICGC;COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q9BY84	DUSP16	P28482	MAPK1	S459	S452P	452	Missense	distal	-7	no	14.430	14.434	EPSD	TCGA;ICGC;COSMIC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q9BY84	DUSP16	P28482	MAPK1	T473	A474T	474	Missense	proximal	1	no	9.347	8.479	EPSD	TCGA;ICGC;COSMIC;CCLE	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q9BY84	DUSP16	P28482	MAPK1	T473	R475K	475	Missense	proximal	2	no	9.347	9.166	EPSD	TCGA;ICGC;COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q9BY84	DUSP16	P28482	MAPK1	S498	L499P	499	Missense	proximal	1	no	3.839	12.649	EPSD	TCGA;ICGC;COSMIC	8.102	Gain
CMGC_MAPK_ERK1_MAPK1_ST	Q9BY84	DUSP16	P28482	MAPK1	S501	P502A	502	Missense	proximal	1	no	14.135	6.505	EPSD	TCGA;ICGC;COSMIC	8.102	Loss
CMGC_MAPK_ERK1_MAPK1_ST	Q9BY84	DUSP16	P28482	MAPK1	S501	L499P	499	Missense	proximal	-2	no	14.135	16.053	EPSD	TCGA;ICGC;COSMIC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q9BY84	DUSP16	P28482	MAPK1	S501	R505Q	505	Missense	distal	4	no	14.135	14.061	EPSD	TCGA;ICGC;COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q9BY84	DUSP16	P28482	MAPK1	S501	S508N	508	Missense	distal	7	no	14.135	14.118	EPSD	TCGA;ICGC;COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q9BY84	DUSP16	P28482	MAPK1	S612	R611Q	611	Missense	proximal	-1	no	10.407	10.386	EPSD	TCGA;ICGC;COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q9BY84	DUSP16	P28482	MAPK1	S612	S609L	609	Missense	distal	-3	no	10.407	10.200	EPSD	TCGA;ICGC;COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q9BY84	DUSP16	P28482	MAPK1	S612	E616D	616	Missense	distal	4	no	10.407	10.337	EPSD	TCGA;ICGC;COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q9BY84	DUSP16	P28482	MAPK1	S617	R611Q	611	Missense	distal	-6	no	14.356	14.333	EPSD	TCGA;ICGC;COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q9BY84	DUSP16	P28482	MAPK1	S617	E616D	616	Missense	proximal	-1	no	14.356	14.316	EPSD	TCGA;ICGC;COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	O75030	MITF	P28482	MAPK1	T23	S29G	29	Missense	distal	6	no	10.611	10.534	EPSD	TCGA;ICGC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	O75030	MITF	P28482	MAPK1	T23	H18R	18	Missense	distal	-5	no	10.611	10.534	EPSD	TCGA;ICGC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	O75030	MITF	P28482	MAPK1	S175	A177T	177	Missense	proximal	2	no	8.206	8.286	EPSD	TCGA;ICGC;COSMIC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	O75030	MITF	P28482	MAPK1	S175	V172L	172	Missense	distal	-3	no	8.206	8.130	EPSD	TCGA;ICGC;COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	O75030	MITF	P28482	MAPK1	S175	P178L	178	Missense	distal	3	no	8.206	8.296	EPSD	TCGA;ICGC;COSMIC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	O75030	MITF	P28482	MAPK1	S175	P171L	171	Missense	distal	-4	no	8.206	7.902	EPSD	TCGA;ICGC;COSMIC;CCLE	8.102	Loss
CMGC_MAPK_ERK1_MAPK1_ST	O75030	MITF	P28482	MAPK1	S180	A177T	177	Missense	distal	-3	no	17.567	17.724	EPSD	TCGA;ICGC;COSMIC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	O75030	MITF	P28482	MAPK1	S180	T186M	186	Missense	distal	6	no	17.567	17.344	EPSD	TCGA;ICGC;COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	O75030	MITF	P28482	MAPK1	S180	P178L	178	Missense	proximal	-2	no	17.567	15.649	EPSD	TCGA;ICGC;COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P03372	ESR1	P28482	MAPK1	S106	P113S	113	Missense	distal	7	no	13.462	13.473	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P03372	ESR1	P28482	MAPK1	S118	P113S	113	Missense	distal	-5	no	12.971	13.045	PhosphoSitePlus;EPSD	TCGA;ICGC;COSMIC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P03372	ESR1	P28482	MAPK1	S167	A166S	166	Missense	proximal	-1	no	8.379	8.372	EPSD	TCGA;ICGC;COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P03372	ESR1	P28482	MAPK1	S167	K171M	171	Missense	distal	4	no	8.379	8.204	EPSD	TCGA;ICGC;COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P03372	ESR1	P28482	MAPK1	S294	W292R	292	Missense	proximal	-2	no	14.197	15.120	EPSD	TCGA;ICGC;COSMIC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P03372	ESR1	P28482	MAPK1	S294	I298M	298	Missense	distal	4	no	14.197	14.175	EPSD	TCGA;ICGC;COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P03372	ESR1	P28482	MAPK1	S294	L291I	291	Missense	distal	-3	no	14.197	14.140	EPSD	TCGA;ICGC;COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P03372	ESR1	P28482	MAPK1	S554	R555H	555	Missense	proximal	1	no	6.399	8.230	EPSD	TCGA;ICGC;COSMIC;GDSC	8.102	Gain
CMGC_MAPK_ERK1_MAPK1_ST	P03372	ESR1	P28482	MAPK1	S576	S575L	575	Missense	proximal	-1	no	8.436	8.420	EPSD	TCGA;ICGC;COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P03372	ESR1	P28482	MAPK1	S576	K581T	581	Missense	distal	5	no	8.436	8.466	EPSD	TCGA;ICGC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P09874	PARP1	P28482	MAPK1	S41	S41L	41	Missense	central	0	yes	14.960	0.000	EPSD	TCGA;ICGC;COSMIC	8.102	Loss
CMGC_MAPK_ERK1_MAPK1_ST	P09874	PARP1	P28482	MAPK1	T361	T368M	368	Missense	distal	7	no	8.042	8.250	EPSD	TCGA;GDSC;CCLE	8.102	Gain
CMGC_MAPK_ERK1_MAPK1_ST	P09874	PARP1	P28482	MAPK1	T361	A363T	363	Missense	proximal	2	no	8.042	8.122	EPSD	TCGA;ICGC;COSMIC	8.102	Gain
CMGC_MAPK_ERK1_MAPK1_ST	P09874	PARP1	P28482	MAPK1	T368	T368M	368	Missense	central	0	yes	13.208	0.000	EPSD	TCGA;GDSC;CCLE	8.102	Loss
CMGC_MAPK_ERK1_MAPK1_ST	P09874	PARP1	P28482	MAPK1	T368	A363T	363	Missense	distal	-5	no	13.208	13.186	EPSD	TCGA;ICGC;COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P09874	PARP1	P28482	MAPK1	T368	P369L	369	Missense	proximal	1	no	13.208	4.398	EPSD	TCGA;ICGC;COSMIC	8.102	Loss
CMGC_MAPK_ERK1_MAPK1_ST	P09874	PARP1	P28482	MAPK1	T368	S375L	375	Missense	distal	7	no	13.208	13.496	EPSD	TCGA;ICGC;COSMIC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P09874	PARP1	P28482	MAPK1	T368	P371L	371	Missense	distal	3	no	13.208	13.297	EPSD	TCGA;ICGC;COSMIC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P09874	PARP1	P28482	MAPK1	T368	V365M	365	Missense	distal	-3	no	13.208	13.077	EPSD	TCGA;ICGC;COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P09874	PARP1	P28482	MAPK1	S372	T368M	368	Missense	distal	-4	no	8.983	8.831	PhosphoSitePlus;EPSD	TCGA;GDSC;CCLE	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P09874	PARP1	P28482	MAPK1	S372	P369L	369	Missense	distal	-3	no	8.983	8.600	PhosphoSitePlus;EPSD	TCGA;ICGC;COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P09874	PARP1	P28482	MAPK1	S372	S375L	375	Missense	distal	3	no	8.983	9.004	PhosphoSitePlus;EPSD	TCGA;ICGC;COSMIC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P09874	PARP1	P28482	MAPK1	S372	P371L	371	Missense	proximal	-1	no	8.983	8.923	PhosphoSitePlus;EPSD	TCGA;ICGC;COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P09874	PARP1	P28482	MAPK1	S372	V365M	365	Missense	distal	-7	no	8.983	8.981	PhosphoSitePlus;EPSD	TCGA;ICGC;COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P09874	PARP1	P28482	MAPK1	T373	T368M	368	Missense	distal	-5	no	10.488	10.538	EPSD;PhosphoSitePlus	TCGA;GDSC;CCLE	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P09874	PARP1	P28482	MAPK1	T373	P369L	369	Missense	distal	-4	no	10.488	10.184	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P09874	PARP1	P28482	MAPK1	T373	S375L	375	Missense	proximal	2	no	10.488	10.369	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P09874	PARP1	P28482	MAPK1	T373	P371L	371	Missense	proximal	-2	no	10.488	8.571	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P09874	PARP1	P28482	MAPK1	S479	H476R	476	Missense	distal	-3	no	14.080	14.409	EPSD	TCGA;ICGC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P09874	PARP1	P28482	MAPK1	S479	F473L	473	Missense	distal	-6	no	14.080	14.098	EPSD	TCGA;ICGC;COSMIC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P09874	PARP1	P28482	MAPK1	S479	A475V	475	Missense	distal	-4	no	14.080	14.019	EPSD	TCGA;ICGC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P09874	PARP1	P28482	MAPK1	S554	V560L	560	Missense	distal	6	no	8.342	8.150	EPSD	TCGA;ICGC;COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P09874	PARP1	P28482	MAPK1	S554	F553L	553	Missense	proximal	-1	no	8.342	8.372	EPSD	TCGA;ICGC;COSMIC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P09874	PARP1	P28482	MAPK1	S554	V560M	560	Missense	distal	6	no	8.342	8.124	EPSD	TCGA;ICGC;COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P09874	PARP1	P28482	MAPK1	S554	L559M	559	Missense	distal	5	no	8.342	8.369	EPSD	TCGA;ICGC;COSMIC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P09874	PARP1	P28482	MAPK1	S721	A719V	719	Missense	proximal	-2	no	7.751	9.025	EPSD	TCGA;COSMIC	8.102	Gain
CMGC_MAPK_ERK1_MAPK1_ST	Q07889	SOS1	P28482	MAPK1	T200	T200A	200	Missense	central	0	yes	8.512	0.000	EPSD	TCGA;ICGC;COSMIC	8.102	Loss
CMGC_MAPK_ERK1_MAPK1_ST	Q07889	SOS1	P28482	MAPK1	T200	S194F	194	Missense	distal	-6	no	8.512	8.428	EPSD	TCGA;ICGC;COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q07889	SOS1	P28482	MAPK1	T200	P193L	193	Missense	distal	-7	no	8.512	8.500	EPSD	TCGA;ICGC;COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q07889	SOS1	P28482	MAPK1	S582	D581N	581	Missense	proximal	-1	no	9.039	9.100	EPSD	TCGA;ICGC;COSMIC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q07889	SOS1	P28482	MAPK1	S582	R576K	576	Missense	distal	-6	no	9.039	9.016	EPSD	TCGA;ICGC;COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q07889	SOS1	P28482	MAPK1	S757	T760I	760	Missense	distal	3	no	15.597	15.662	EPSD	TCGA;ICGC;COSMIC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q07889	SOS1	P28482	MAPK1	S818	D813H	813	Missense	distal	-5	no	14.069	14.124	EPSD	TCGA	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q07889	SOS1	P28482	MAPK1	T1054	M1050I	1050	Missense	distal	-4	no	13.345	13.140	EPSD	TCGA;ICGC;COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q07889	SOS1	P28482	MAPK1	T1054	E1059G	1059	Missense	distal	5	no	13.345	13.370	EPSD	TCGA;ICGC;COSMIC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q07889	SOS1	P28482	MAPK1	T1054	M1050T	1050	Missense	distal	-4	no	13.345	13.498	EPSD	TCGA;ICGC;COSMIC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q07889	SOS1	P28482	MAPK1	S1064	E1059G	1059	Missense	distal	-5	no	8.454	8.496	EPSD	TCGA;ICGC;COSMIC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q07889	SOS1	P28482	MAPK1	S1082	S1082Y	1082	Missense	central	0	yes	16.690	0.000	EPSD	TCGA;ICGC;COSMIC	8.102	Loss
CMGC_MAPK_ERK1_MAPK1_ST	Q07889	SOS1	P28482	MAPK1	T1088	P1090L	1090	Missense	proximal	2	no	14.309	14.161	EPSD	TCGA;ICGC;COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q07889	SOS1	P28482	MAPK1	T1088	S1082Y	1082	Missense	distal	-6	no	14.309	14.194	EPSD	TCGA;ICGC;COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q07889	SOS1	P28482	MAPK1	S1132	S1134C	1134	Missense	proximal	2	no	10.454	10.222	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q07889	SOS1	P28482	MAPK1	S1178	S1173P	1173	Missense	distal	-5	no	13.573	13.499	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q07889	SOS1	P28482	MAPK1	S1193	S1197L	1197	Missense	distal	4	no	15.592	15.482	EPSD;PhosphoSitePlus	TCGA;COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q07889	SOS1	P28482	MAPK1	S1210	I1204V	1204	Missense	distal	-6	no	17.240	17.281	EPSD	TCGA;COSMIC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q07889	SOS1	P28482	MAPK1	S1229	P1236S	1236	Missense	distal	7	no	14.269	14.280	EPSD	TCGA;ICGC;COSMIC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q07889	SOS1	P28482	MAPK1	S1254	P1260R	1260	Missense	distal	6	no	14.219	14.112	EPSD	TCGA;COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q07889	SOS1	P28482	MAPK1	T1257	P1260S	1260	Missense	distal	3	no	15.601	15.670	EPSD	TCGA;ICGC;COSMIC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q07889	SOS1	P28482	MAPK1	T1257	P1260R	1260	Missense	distal	3	no	15.601	15.647	EPSD	TCGA;COSMIC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q07889	SOS1	P28482	MAPK1	T1263	P1260S	1260	Missense	distal	-3	no	18.139	17.963	EPSD	TCGA;ICGC;COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q07889	SOS1	P28482	MAPK1	T1263	P1266L	1266	Missense	distal	3	no	18.139	18.229	EPSD	TCGA;COSMIC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q07889	SOS1	P28482	MAPK1	T1263	P1260R	1260	Missense	distal	-3	no	18.139	18.120	EPSD	TCGA;COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q07889	SOS1	P28482	MAPK1	S1265	P1260S	1260	Missense	distal	-5	no	15.480	15.554	EPSD	TCGA;ICGC;COSMIC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q07889	SOS1	P28482	MAPK1	S1265	P1266L	1266	Missense	proximal	1	no	15.480	6.670	EPSD	TCGA;COSMIC	8.102	Loss
CMGC_MAPK_ERK1_MAPK1_ST	Q07889	SOS1	P28482	MAPK1	S1265	P1260R	1260	Missense	distal	-5	no	15.480	15.528	EPSD	TCGA;COSMIC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q13614	MTMR2	P28482	MAPK1	S29	S33L	33	Missense	distal	4	no	8.462	8.353	EPSD	TCGA;ICGC;COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q13614	MTMR2	P28482	MAPK1	S29	E34D	34	Missense	distal	5	no	8.462	8.532	EPSD	TCGA;ICGC;COSMIC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q13614	MTMR2	P28482	MAPK1	S58	L64P	64	Missense	distal	6	no	13.641	14.048	PhosphoSitePlus	TCGA;ICGC;COSMIC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q13614	MTMR2	P28482	MAPK1	S558	V563I	563	Missense	distal	5	no	8.303	8.129	EPSD	TCGA;COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q13614	MTMR2	P28482	MAPK1	S622	Q615H	615	Missense	distal	-7	no	8.489	8.470	EPSD	TCGA;COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q13614	MTMR2	P28482	MAPK1	T637	V642I	642	Missense	distal	5	no	14.782	14.608	EPSD	TCGA;COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q96EP5	DAZAP1	P28482	MAPK1	T86	I80F	80	Missense	distal	-6	no	15.831	15.848	EPSD	TCGA;ICGC;COSMIC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q96EP5	DAZAP1	P28482	MAPK1	T269	G273S	273	Missense	distal	4	no	13.910	13.959	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q96EP5	DAZAP1	P28482	MAPK1	T269	I266M	266	Missense	distal	-3	no	13.910	13.913	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q96EP5	DAZAP1	P28482	MAPK1	T269	T263A	263	Missense	distal	-6	no	13.910	13.920	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q96EP5	DAZAP1	P28482	MAPK1	T315	P316L	316	Missense	proximal	1	no	17.191	8.382	PhosphoSitePlus;EPSD	TCGA;ICGC;COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q96EP5	DAZAP1	P28482	MAPK1	T315	P316S	316	Missense	proximal	1	no	17.191	7.796	PhosphoSitePlus;EPSD	TCGA;ICGC;COSMIC	8.102	Loss
CMGC_MAPK_ERK1_MAPK1_ST	Q96EP5	DAZAP1	P28482	MAPK1	T315	A319V	319	Missense	distal	4	no	17.191	17.185	PhosphoSitePlus;EPSD	TCGA;ICGC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q13322	GRB10	P28482	MAPK1	T23	D29Y	29	Missense	distal	6	no	15.860	15.287	EPSD	TCGA;ICGC;COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q13322	GRB10	P28482	MAPK1	T23	Q22K	22	Missense	proximal	-1	no	15.860	15.914	EPSD	TCGA;ICGC;COSMIC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q13322	GRB10	P28482	MAPK1	T23	T23I	23	Missense	central	0	yes	15.860	0.000	EPSD	TCGA;ICGC;COSMIC	8.102	Loss
CMGC_MAPK_ERK1_MAPK1_ST	Q13322	GRB10	P28482	MAPK1	T23	R25H	25	Missense	proximal	2	no	15.860	15.617	EPSD	TCGA;ICGC;COSMIC;GDSC;CCLE	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q13322	GRB10	P28482	MAPK1	S104	R108T	108	Missense	distal	4	no	13.383	13.292	EPSD	TCGA;COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q13322	GRB10	P28482	MAPK1	S104	R111H	111	Missense	distal	7	no	13.383	13.602	EPSD	TCGA	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q13322	GRB10	P28482	MAPK1	T155	P161A	161	Missense	distal	6	no	12.625	12.328	EPSD	TCGA;COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q13322	GRB10	P28482	MAPK1	T155	S158Y	158	Missense	distal	3	no	12.625	12.683	EPSD	TCGA;COSMIC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q13322	GRB10	P28482	MAPK1	S418	T422M	422	Missense	distal	4	no	16.613	16.538	EPSD	TCGA;COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q13322	GRB10	P28482	MAPK1	S418	S421L	421	Missense	distal	3	no	16.613	16.633	EPSD	TCGA;COSMIC;CCLE	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q13322	GRB10	P28482	MAPK1	S418	R425H	425	Missense	distal	7	no	16.613	16.832	EPSD	TCGA;COSMIC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q13322	GRB10	P28482	MAPK1	S421	T422M	422	Missense	proximal	1	no	8.588	2.384	EPSD	TCGA;COSMIC	8.102	Loss
CMGC_MAPK_ERK1_MAPK1_ST	Q13322	GRB10	P28482	MAPK1	S421	S421L	421	Missense	central	0	yes	8.588	0.000	EPSD	TCGA;COSMIC;CCLE	8.102	Loss
CMGC_MAPK_ERK1_MAPK1_ST	Q13322	GRB10	P28482	MAPK1	S421	R425H	425	Missense	distal	4	no	8.588	8.447	EPSD	TCGA;COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q13322	GRB10	P28482	MAPK1	T422	T422M	422	Missense	central	0	yes	13.463	0.000	EPSD	TCGA;COSMIC	8.102	Loss
CMGC_MAPK_ERK1_MAPK1_ST	Q13322	GRB10	P28482	MAPK1	T422	S421L	421	Missense	proximal	-1	no	13.463	13.447	EPSD	TCGA;COSMIC;CCLE	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q13322	GRB10	P28482	MAPK1	T422	R425H	425	Missense	distal	3	no	13.463	13.506	EPSD	TCGA;COSMIC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q13322	GRB10	P28482	MAPK1	T422	E429D	429	Missense	distal	7	no	13.463	13.519	EPSD	TCGA	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q13322	GRB10	P28482	MAPK1	S476	I471V	471	Missense	distal	-5	no	13.998	13.885	EPSD;PhosphoSitePlus	TCGA;COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q13322	GRB10	P28482	MAPK1	S476	G473C	473	Missense	distal	-3	no	13.998	13.484	EPSD;PhosphoSitePlus	TCGA;COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q13322	GRB10	P28482	MAPK1	S476	P480L	480	Missense	distal	4	no	13.998	13.878	EPSD;PhosphoSitePlus	TCGA;COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q13322	GRB10	P28482	MAPK1	S476	S476I	476	Missense	central	0	yes	13.998	0.000	EPSD;PhosphoSitePlus	TCGA;COSMIC	8.102	Loss
CMGC_MAPK_ERK1_MAPK1_ST	O95600	KLF8	P28482	MAPK1	S342	D347H	347	Missense	distal	5	no	10.183	10.012	EPSD	TCGA;ICGC;COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	O95600	KLF8	P28482	MAPK1	S342	D338H	338	Missense	distal	-4	no	10.183	9.956	EPSD	TCGA;ICGC;COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	O95600	KLF8	P28482	MAPK1	S342	C339Y	339	Missense	distal	-3	no	10.183	10.440	EPSD	TCGA;ICGC;COSMIC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	O95600	KLF8	P28482	MAPK1	S342	R341S	341	Missense	proximal	-1	no	10.183	10.159	EPSD	TCGA;ICGC;COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	O95600	KLF8	P28482	MAPK1	S342	R335W	335	Missense	distal	-7	no	10.183	10.132	EPSD	TCGA;ICGC;COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P84022	SMAD3	P28482	MAPK1	T8	P9S	9	Missense	proximal	1	no	15.702	6.307	EPSD	TCGA;ICGC;COSMIC	8.102	Loss
CMGC_MAPK_ERK1_MAPK1_ST	P84022	SMAD3	P28482	MAPK1	T132	L135V	135	Missense	distal	3	no	13.028	12.996	EPSD	TCGA;ICGC;COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P84022	SMAD3	P28482	MAPK1	T132	Q128H	128	Missense	distal	-4	no	13.028	12.979	EPSD	TCGA;ICGC;COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P84022	SMAD3	P28482	MAPK1	T179	E178D	178	Missense	proximal	-1	no	14.377	14.337	EPSD;PhosphoSitePlus	TCGA;COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P84022	SMAD3	P28482	MAPK1	S204	S204Y	204	Missense	central	0	yes	14.774	0.000	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	8.102	Loss
CMGC_MAPK_ERK1_MAPK1_ST	P84022	SMAD3	P28482	MAPK1	S204	S199N	199	Missense	distal	-5	no	14.774	14.726	EPSD;PhosphoSitePlus	TCGA	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P84022	SMAD3	P28482	MAPK1	S208	S204Y	204	Missense	distal	-4	no	16.481	15.892	PhosphoSitePlus;EPSD	TCGA;ICGC;COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P84022	SMAD3	P28482	MAPK1	T412	S416F	416	Missense	distal	4	no	9.466	9.288	EPSD	TCGA;ICGC;COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P84022	SMAD3	P28482	MAPK1	T412	S418I	418	Missense	distal	6	no	9.466	8.799	EPSD	TCGA;COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P84022	SMAD3	P28482	MAPK1	T412	P417L	417	Missense	distal	5	no	9.466	9.253	EPSD	TCGA;ICGC;COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P84022	SMAD3	P28482	MAPK1	T412	S418N	418	Missense	distal	6	no	9.466	9.370	EPSD	TCGA;ICGC;COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P84022	SMAD3	P28482	MAPK1	T412	Q405L	405	Missense	distal	-7	no	9.466	9.451	EPSD	TCGA;ICGC;COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P84022	SMAD3	P28482	MAPK1	S416	S416F	416	Missense	central	0	yes	12.685	0.000	EPSD	TCGA;ICGC;COSMIC	8.102	Loss
CMGC_MAPK_ERK1_MAPK1_ST	P84022	SMAD3	P28482	MAPK1	S416	S418I	418	Missense	proximal	2	no	12.685	12.542	EPSD	TCGA;COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P84022	SMAD3	P28482	MAPK1	S416	R420H	420	Missense	distal	4	no	12.685	12.544	EPSD	TCGA;ICGC;COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P84022	SMAD3	P28482	MAPK1	S416	S423R	423	Missense	distal	7	no	12.685	12.689	EPSD	TCGA;ICGC;COSMIC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P84022	SMAD3	P28482	MAPK1	S416	P417L	417	Missense	proximal	1	no	12.685	3.876	EPSD	TCGA;ICGC;COSMIC	8.102	Loss
CMGC_MAPK_ERK1_MAPK1_ST	P84022	SMAD3	P28482	MAPK1	S416	S418N	418	Missense	proximal	2	no	12.685	12.637	EPSD	TCGA;ICGC;COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P84022	SMAD3	P28482	MAPK1	S422	P417L	417	Missense	distal	-5	no	7.996	8.145	EPSD	TCGA;ICGC;COSMIC	8.102	Gain
CMGC_MAPK_ERK1_MAPK1_ST	Q9NZ72	STMN3	P28482	MAPK1	S60	F54L	54	Missense	distal	-6	no	14.667	14.685	EPSD	TCGA;COSMIC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q9NZ72	STMN3	P28482	MAPK1	S60	S65F	65	Missense	distal	5	no	14.667	14.470	EPSD	TCGA	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q9NZ72	STMN3	P28482	MAPK1	S65	S65F	65	Missense	central	0	yes	14.438	0.000	EPSD	TCGA	8.102	Loss
CMGC_MAPK_ERK1_MAPK1_ST	Q9NZ72	STMN3	P28482	MAPK1	S68	S65F	65	Missense	distal	-3	no	16.119	15.886	PhosphoSitePlus	TCGA	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q9NZ72	STMN3	P28482	MAPK1	S73	P74S	74	Missense	proximal	1	no	15.549	6.155	EPSD	TCGA;COSMIC	8.102	Loss
CMGC_MAPK_ERK1_MAPK1_ST	Q96I25	RBM17	P28482	MAPK1	S48	A52T	52	Missense	distal	4	no	8.317	8.298	EPSD	TCGA;ICGC;COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q96I25	RBM17	P28482	MAPK1	T71	V69A	69	Missense	proximal	-2	no	14.334	13.059	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q96I25	RBM17	P28482	MAPK1	S222	E215K	215	Missense	distal	-7	no	17.979	17.972	PhosphoSitePlus;EPSD	TCGA;ICGC;COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P12980	LYL1	P28482	MAPK1	S25	A18E	18	Missense	distal	-7	no	14.308	14.315	EPSD	TCGA;ICGC;COSMIC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P12980	LYL1	P28482	MAPK1	S25	C22R	22	Missense	distal	-3	no	14.308	14.992	EPSD	TCGA;ICGC;COSMIC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P12980	LYL1	P28482	MAPK1	S36	E43D	43	Missense	distal	7	no	17.074	17.129	PhosphoSitePlus	TCGA;ICGC;COSMIC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P12980	LYL1	P28482	MAPK1	S52	G59S	59	Missense	distal	7	no	14.251	14.182	EPSD	TCGA;ICGC;COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P12980	LYL1	P28482	MAPK1	S134	E137Q	137	Missense	distal	3	no	9.127	9.204	EPSD	TCGA;ICGC;COSMIC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P12980	LYL1	P28482	MAPK1	S134	R132I	132	Missense	proximal	-2	no	9.127	9.051	EPSD	TCGA;ICGC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P51812	RPS6KA3	P28482	MAPK1	S227	E233K	233	Missense	distal	6	no	10.418	10.442	EPSD	TCGA;ICGC;COSMIC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P51812	RPS6KA3	P28482	MAPK1	S227	S227Y	227	Missense	central	0	yes	10.418	0.000	EPSD	TCGA;ICGC	8.102	Loss
CMGC_MAPK_ERK1_MAPK1_ST	P51812	RPS6KA3	P28482	MAPK1	T354	E360Q	360	Missense	distal	6	no	8.461	8.140	EPSD	TCGA;ICGC;COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P51812	RPS6KA3	P28482	MAPK1	T354	G349D	349	Missense	distal	-5	no	8.461	8.463	EPSD	TCGA;ICGC;COSMIC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P51812	RPS6KA3	P28482	MAPK1	T354	F355L	355	Missense	proximal	1	no	8.461	6.220	EPSD	TCGA;ICGC;COSMIC	8.102	Loss
CMGC_MAPK_ERK1_MAPK1_ST	P51812	RPS6KA3	P28482	MAPK1	T365	E360Q	360	Missense	distal	-5	no	13.775	13.874	EPSD	TCGA;ICGC;COSMIC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P51812	RPS6KA3	P28482	MAPK1	S369	P374S	374	Missense	distal	5	no	15.616	15.634	EPSD	TCGA;ICGC;COSMIC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P51812	RPS6KA3	P28482	MAPK1	S386	T391A	391	Missense	distal	5	no	8.307	8.221	EPSD	TCGA;ICGC;COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P51812	RPS6KA3	P28482	MAPK1	S386	L381H	381	Missense	distal	-5	no	8.307	8.283	EPSD	TCGA;ICGC;COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P51812	RPS6KA3	P28482	MAPK1	S386	R383W	383	Missense	distal	-3	no	8.307	7.608	EPSD	TCGA;ICGC;COSMIC;GDSC;CCLE	8.102	Loss
CMGC_MAPK_ERK1_MAPK1_ST	P51812	RPS6KA3	P28482	MAPK1	T577	F584V	584	Missense	distal	7	no	15.244	15.179	EPSD	TCGA;COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P51812	RPS6KA3	P28482	MAPK1	T577	F584S	584	Missense	distal	7	no	15.244	14.896	EPSD	TCGA;ICGC;COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P51812	RPS6KA3	P28482	MAPK1	T625	N620I	620	Missense	distal	-5	no	10.201	10.384	EPSD	TCGA;ICGC;COSMIC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P51812	RPS6KA3	P28482	MAPK1	T625	P622S	622	Missense	distal	-3	no	10.201	10.024	EPSD	TCGA;ICGC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P51812	RPS6KA3	P28482	MAPK1	S715	G722S	722	Missense	distal	7	no	14.509	14.440	EPSD	TCGA;ICGC;COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P51812	RPS6KA3	P28482	MAPK1	S715	R712C	712	Missense	distal	-3	no	14.509	13.825	EPSD	TCGA;ICGC;COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P51812	RPS6KA3	P28482	MAPK1	S715	R712H	712	Missense	distal	-3	no	14.509	14.179	EPSD	TCGA;ICGC;COSMIC;GDSC;CCLE	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P51812	RPS6KA3	P28482	MAPK1	T725	L726V	726	Missense	proximal	1	no	10.124	9.393	EPSD	TCGA;COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P51812	RPS6KA3	P28482	MAPK1	T725	G722S	722	Missense	distal	-3	no	10.124	10.136	EPSD	TCGA;ICGC;COSMIC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P08047	SP1	P28482	MAPK1	S59	L61V	61	Missense	proximal	2	no	13.407	13.501	PhosphoSitePlus;EPSD	TCGA;ICGC;COSMIC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P08047	SP1	P28482	MAPK1	S59	S59F	59	Missense	central	0	yes	13.407	0.000	PhosphoSitePlus;EPSD	TCGA;ICGC;COSMIC	8.102	Loss
CMGC_MAPK_ERK1_MAPK1_ST	P08047	SP1	P28482	MAPK1	S73	S69N	69	Missense	distal	-4	no	13.859	13.900	EPSD	TCGA;ICGC;COSMIC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P08047	SP1	P28482	MAPK1	S73	C68R	68	Missense	distal	-5	no	13.859	13.629	EPSD	TCGA;ICGC;COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P08047	SP1	P28482	MAPK1	S73	P74S	74	Missense	proximal	1	no	13.859	4.464	EPSD	TCGA;ICGC;COSMIC	8.102	Loss
CMGC_MAPK_ERK1_MAPK1_ST	P08047	SP1	P28482	MAPK1	S73	S78N	78	Missense	distal	5	no	13.859	13.786	EPSD	TCGA;ICGC;COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P08047	SP1	P28482	MAPK1	T278	V272I	272	Missense	distal	-6	no	12.616	12.575	EPSD	TCGA;ICGC;COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P08047	SP1	P28482	MAPK1	T278	S271N	271	Missense	distal	-7	no	12.616	12.618	EPSD	TCGA;ICGC;COSMIC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P08047	SP1	P28482	MAPK1	T453	S446C	446	Missense	distal	-7	no	12.721	12.689	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P08047	SP1	P28482	MAPK1	S588	D590E	590	Missense	proximal	2	no	14.768	14.716	EPSD	TCGA;ICGC;COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P08047	SP1	P28482	MAPK1	S588	S588N	588	Missense	central	0	yes	14.768	0.000	EPSD	TCGA;ICGC;COSMIC	8.102	Loss
CMGC_MAPK_ERK1_MAPK1_ST	P08047	SP1	P28482	MAPK1	T739	I744F	744	Missense	distal	5	no	13.402	13.522	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P08047	SP1	P28482	MAPK1	T739	A742T	742	Missense	distal	3	no	13.402	13.386	EPSD;PhosphoSitePlus	TCGA;ICGC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P08047	SP1	P28482	MAPK1	T739	G736S	736	Missense	distal	-3	no	13.402	13.414	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P55211	CASP9	P28482	MAPK1	S87	D83Y	83	Missense	distal	-4	no	9.260	8.601	EPSD	TCGA;ICGC;COSMIC;CCLE	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P55211	CASP9	P28482	MAPK1	S87	G81D	81	Missense	distal	-6	no	9.260	9.326	EPSD	TCGA;ICGC;COSMIC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P55211	CASP9	P28482	MAPK1	T107	E114D	114	Missense	distal	7	no	14.563	14.618	EPSD	TCGA;ICGC;COSMIC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P55211	CASP9	P28482	MAPK1	T107	P101A	101	Missense	distal	-6	no	14.563	14.524	EPSD	TCGA;ICGC;COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P55211	CASP9	P28482	MAPK1	S302	S307F	307	Missense	distal	5	no	15.851	15.654	EPSD	TCGA;ICGC;COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P55211	CASP9	P28482	MAPK1	S307	S307F	307	Missense	central	0	yes	12.776	0.000	EPSD	TCGA;ICGC;COSMIC	8.102	Loss
CMGC_MAPK_ERK1_MAPK1_ST	Q16828	DUSP6	P28482	MAPK1	S159	S154W	154	Missense	distal	-5	no	13.542	13.792	PhosphoSitePlus;EPSD	TCGA;COSMIC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q16828	DUSP6	P28482	MAPK1	S197	P204L	204	Missense	distal	7	no	14.950	15.249	EPSD;PhosphoSitePlus	TCGA;COSMIC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q16828	DUSP6	P28482	MAPK1	S197	S200T	200	Missense	distal	3	no	14.950	14.943	EPSD;PhosphoSitePlus	TCGA;COSMIC;GDSC;CCLE	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q16828	DUSP6	P28482	MAPK1	S197	S194L	194	Missense	distal	-3	no	14.950	14.743	EPSD;PhosphoSitePlus	TCGA;COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q16828	DUSP6	P28482	MAPK1	S205	P204L	204	Missense	proximal	-1	no	8.150	8.090	EPSD	TCGA;COSMIC	8.102	Loss
CMGC_MAPK_ERK1_MAPK1_ST	Q16828	DUSP6	P28482	MAPK1	S205	S200T	200	Missense	distal	-5	no	8.150	8.178	EPSD	TCGA;COSMIC;GDSC;CCLE	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q16828	DUSP6	P28482	MAPK1	S205	P212S	212	Missense	distal	7	no	8.150	8.160	EPSD	TCGA;COSMIC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q9Y6W5	WASF2	P28482	MAPK1	T129	P130S	130	Missense	proximal	1	no	12.926	3.531	EPSD	TCGA;ICGC	8.102	Loss
CMGC_MAPK_ERK1_MAPK1_ST	Q9Y6W5	WASF2	P28482	MAPK1	T129	L136V	136	Missense	distal	7	no	12.926	12.920	EPSD	TCGA;ICGC;COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q9Y6W5	WASF2	P28482	MAPK1	T129	L133I	133	Missense	distal	4	no	12.926	12.869	EPSD	TCGA;ICGC;COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q9Y6W5	WASF2	P28482	MAPK1	T137	P130S	130	Missense	distal	-7	no	12.338	12.334	EPSD	TCGA;ICGC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q9Y6W5	WASF2	P28482	MAPK1	T137	L136V	136	Missense	proximal	-1	no	12.338	12.372	EPSD	TCGA;ICGC;COSMIC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q9Y6W5	WASF2	P28482	MAPK1	T137	L133I	133	Missense	distal	-4	no	12.338	11.972	EPSD	TCGA;ICGC;COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q9Y6W5	WASF2	P28482	MAPK1	S257	F262L	262	Missense	distal	5	no	14.282	14.248	EPSD	TCGA;ICGC;COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q9Y6W5	WASF2	P28482	MAPK1	S257	S254T	254	Missense	distal	-3	no	14.282	14.249	EPSD	TCGA;ICGC;COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q9Y6W5	WASF2	P28482	MAPK1	S257	S263F	263	Missense	distal	6	no	14.282	13.841	EPSD	TCGA;ICGC;COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q9Y6W5	WASF2	P28482	MAPK1	S257	Q251R	251	Missense	distal	-6	no	14.282	14.305	EPSD	TCGA;ICGC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q9Y6W5	WASF2	P28482	MAPK1	S257	D253E	253	Missense	distal	-4	no	14.282	14.267	EPSD	TCGA;ICGC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q9Y6W5	WASF2	P28482	MAPK1	S259	F262L	262	Missense	distal	3	no	14.368	14.326	EPSD	TCGA;ICGC;COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q9Y6W5	WASF2	P28482	MAPK1	S259	S254T	254	Missense	distal	-5	no	14.368	14.397	EPSD	TCGA;ICGC;COSMIC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q9Y6W5	WASF2	P28482	MAPK1	S259	S263F	263	Missense	distal	4	no	14.368	14.191	EPSD	TCGA;ICGC;COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q9Y6W5	WASF2	P28482	MAPK1	S259	D253E	253	Missense	distal	-6	no	14.368	14.356	EPSD	TCGA;ICGC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q9Y6W5	WASF2	P28482	MAPK1	S296	P297L	297	Missense	proximal	1	no	16.752	7.942	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	8.102	Loss
CMGC_MAPK_ERK1_MAPK1_ST	Q9Y6W5	WASF2	P28482	MAPK1	S296	P297S	297	Missense	proximal	1	no	16.752	7.357	EPSD;PhosphoSitePlus	TCGA;ICGC	8.102	Loss
CMGC_MAPK_ERK1_MAPK1_ST	Q9Y6W5	WASF2	P28482	MAPK1	S343	G345W	345	Missense	proximal	2	no	13.807	13.534	EPSD	TCGA;ICGC;COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q9Y6W5	WASF2	P28482	MAPK1	S343	G345E	345	Missense	proximal	2	no	13.807	13.721	EPSD	TCGA;ICGC;COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q9Y6W5	WASF2	P28482	MAPK1	T346	S351L	351	Missense	distal	5	no	17.201	16.970	EPSD	TCGA;ICGC;COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q9Y6W5	WASF2	P28482	MAPK1	T346	G345W	345	Missense	proximal	-1	no	17.201	17.134	EPSD	TCGA;ICGC;COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q9Y6W5	WASF2	P28482	MAPK1	T346	G345E	345	Missense	proximal	-1	no	17.201	17.240	EPSD	TCGA;ICGC;COSMIC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q9Y6W5	WASF2	P28482	MAPK1	S351	S351L	351	Missense	central	0	yes	17.830	0.000	EPSD	TCGA;ICGC;COSMIC	8.102	Loss
CMGC_MAPK_ERK1_MAPK1_ST	Q9Y6W5	WASF2	P28482	MAPK1	S351	G345W	345	Missense	distal	-6	no	17.830	17.661	EPSD	TCGA;ICGC;COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q9Y6W5	WASF2	P28482	MAPK1	S351	G345E	345	Missense	distal	-6	no	17.830	17.884	EPSD	TCGA;ICGC;COSMIC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	O94953	KDM4B	P28482	MAPK1	S153	L154F	154	Missense	proximal	1	no	7.521	9.762	EPSD	TCGA;ICGC	8.102	Gain
CMGC_MAPK_ERK1_MAPK1_ST	O94953	KDM4B	P28482	MAPK1	T185	E191K	191	Missense	distal	6	no	8.535	8.558	EPSD	TCGA;ICGC;COSMIC;CCLE	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	O94953	KDM4B	P28482	MAPK1	T305	Q306K	306	Missense	proximal	1	no	10.333	0.308	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	8.102	Loss
CMGC_MAPK_ERK1_MAPK1_ST	O94953	KDM4B	P28482	MAPK1	T305	Y300H	300	Missense	distal	-5	no	10.333	10.252	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	O94953	KDM4B	P28482	MAPK1	S352	R346W	346	Missense	distal	-6	no	15.356	15.136	PhosphoSitePlus;EPSD	TCGA;ICGC;COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	O94953	KDM4B	P28482	MAPK1	S566	T571M	571	Missense	distal	5	no	17.766	17.635	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	O94953	KDM4B	P28482	MAPK1	S566	G572V	572	Missense	distal	6	no	17.766	17.628	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	O94953	KDM4B	P28482	MAPK1	S622	P623T	623	Missense	proximal	1	no	15.025	6.526	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	8.102	Loss
CMGC_MAPK_ERK1_MAPK1_ST	O94953	KDM4B	P28482	MAPK1	S622	S622P	622	Missense	central	0	yes	15.025	0.000	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	8.102	Loss
CMGC_MAPK_ERK1_MAPK1_ST	O94953	KDM4B	P28482	MAPK1	S622	R621Q	621	Missense	proximal	-1	no	15.025	15.003	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	O94953	KDM4B	P28482	MAPK1	S638	E635K	635	Missense	distal	-3	no	13.511	13.433	EPSD	TCGA;ICGC;COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	O94953	KDM4B	P28482	MAPK1	S638	F640Y	640	Missense	proximal	2	no	13.511	13.475	EPSD	TCGA;COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	O94953	KDM4B	P28482	MAPK1	S638	G642E	642	Missense	distal	4	no	13.511	13.533	EPSD	TCGA;ICGC;COSMIC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	O94953	KDM4B	P28482	MAPK1	S641	G642E	642	Missense	proximal	1	no	7.605	8.899	EPSD	TCGA;ICGC;COSMIC	8.102	Gain
CMGC_MAPK_ERK1_MAPK1_ST	O94953	KDM4B	P28482	MAPK1	T1065	R1060H	1060	Missense	distal	-5	no	14.614	14.692	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC;CCLE	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q15788	NCOA1	P28482	MAPK1	S16	S22L	22	Missense	distal	6	no	12.301	11.895	EPSD	TCGA;ICGC;COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q15788	NCOA1	P28482	MAPK1	S22	S22L	22	Missense	central	0	yes	15.676	0.000	EPSD	TCGA;ICGC;COSMIC	8.102	Loss
CMGC_MAPK_ERK1_MAPK1_ST	Q15788	NCOA1	P28482	MAPK1	S325	R320H	320	Missense	distal	-5	no	16.048	16.125	EPSD	TCGA;ICGC;COSMIC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q15788	NCOA1	P28482	MAPK1	S325	R329K	329	Missense	distal	4	no	16.048	16.058	EPSD	TCGA;ICGC;COSMIC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q15788	NCOA1	P28482	MAPK1	S325	G321S	321	Missense	distal	-4	no	16.048	16.314	EPSD	TCGA;ICGC;COSMIC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q15788	NCOA1	P28482	MAPK1	S325	A323V	323	Missense	proximal	-2	no	16.048	17.322	EPSD	TCGA;ICGC;COSMIC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q15788	NCOA1	P28482	MAPK1	S325	G321D	321	Missense	distal	-4	no	16.048	16.384	EPSD	TCGA;ICGC;COSMIC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q15788	NCOA1	P28482	MAPK1	S325	R329G	329	Missense	distal	4	no	16.048	16.022	EPSD	TCGA;ICGC;COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q15788	NCOA1	P28482	MAPK1	S372	H368Y	368	Missense	distal	-4	no	15.125	14.693	EPSD	TCGA;ICGC;COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q15788	NCOA1	P28482	MAPK1	S372	S372C	372	Missense	central	0	yes	15.125	0.000	EPSD	TCGA;ICGC;COSMIC	8.102	Loss
CMGC_MAPK_ERK1_MAPK1_ST	Q15788	NCOA1	P28482	MAPK1	S372	G370R	370	Missense	proximal	-2	no	15.125	16.500	EPSD	TCGA;ICGC;COSMIC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q15788	NCOA1	P28482	MAPK1	S372	D376E	376	Missense	distal	4	no	15.125	15.195	EPSD	TCGA;ICGC;COSMIC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q15788	NCOA1	P28482	MAPK1	S395	P388L	388	Missense	distal	-7	no	13.004	12.991	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q15788	NCOA1	P28482	MAPK1	S517	V519I	519	Missense	proximal	2	no	15.224	15.106	EPSD	TCGA;ICGC;COSMIC;GDSC;CCLE	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q15788	NCOA1	P28482	MAPK1	S517	S513L	513	Missense	distal	-4	no	15.224	15.003	EPSD	TCGA;ICGC;COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q15788	NCOA1	P28482	MAPK1	S517	P518S	518	Missense	proximal	1	no	15.224	5.829	EPSD	TCGA;ICGC;COSMIC	8.102	Loss
CMGC_MAPK_ERK1_MAPK1_ST	Q15788	NCOA1	P28482	MAPK1	S517	S516R	516	Missense	proximal	-1	no	15.224	15.248	EPSD	TCGA;ICGC;COSMIC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q15788	NCOA1	P28482	MAPK1	S517	S513A	513	Missense	distal	-4	no	15.224	15.014	EPSD	TCGA;ICGC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q15788	NCOA1	P28482	MAPK1	T539	S540Y	540	Missense	proximal	1	no	5.953	8.339	EPSD	TCGA;ICGC	8.102	Gain
CMGC_MAPK_ERK1_MAPK1_ST	Q15788	NCOA1	P28482	MAPK1	S558	S551F	551	Missense	distal	-7	no	13.320	13.300	EPSD	TCGA;ICGC;COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q15788	NCOA1	P28482	MAPK1	S569	R572T	572	Missense	distal	3	no	14.778	14.794	EPSD	TCGA;ICGC;COSMIC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q15788	NCOA1	P28482	MAPK1	S569	S566A	566	Missense	distal	-3	no	14.778	14.587	EPSD	TCGA;ICGC;COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q15788	NCOA1	P28482	MAPK1	S679	S672L	672	Missense	distal	-7	no	9.807	9.800	EPSD	TCGA;ICGC;COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q15788	NCOA1	P28482	MAPK1	S679	S675Y	675	Missense	distal	-4	no	9.807	9.219	EPSD	TCGA;ICGC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q15788	NCOA1	P28482	MAPK1	S679	R686W	686	Missense	distal	7	no	9.807	10.779	EPSD	TCGA;ICGC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q15788	NCOA1	P28482	MAPK1	S698	S698R	698	Missense	central	0	yes	14.664	0.000	EPSD	TCGA;ICGC;COSMIC	8.102	Loss
CMGC_MAPK_ERK1_MAPK1_ST	Q15788	NCOA1	P28482	MAPK1	T763	L766M	766	Missense	distal	3	no	14.630	14.626	EPSD	TCGA;ICGC;COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q15788	NCOA1	P28482	MAPK1	T763	L768V	768	Missense	distal	5	no	14.630	14.719	EPSD	TCGA;ICGC;COSMIC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q15788	NCOA1	P28482	MAPK1	T763	K758N	758	Missense	distal	-5	no	14.630	14.654	EPSD	TCGA;ICGC;COSMIC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q15788	NCOA1	P28482	MAPK1	T763	L760V	760	Missense	distal	-3	no	14.630	14.707	EPSD	TCGA;ICGC;COSMIC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q15788	NCOA1	P28482	MAPK1	T789	P794H	794	Missense	distal	5	no	14.030	13.903	EPSD	TCGA;ICGC;COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q15788	NCOA1	P28482	MAPK1	T789	T792I	792	Missense	distal	3	no	14.030	14.096	EPSD	TCGA;ICGC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q15788	NCOA1	P28482	MAPK1	T979	I983M	983	Missense	distal	4	no	12.582	12.560	EPSD	TCGA;ICGC;COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q15788	NCOA1	P28482	MAPK1	T979	P975T	975	Missense	distal	-4	no	12.582	12.268	EPSD	TCGA;ICGC;COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q15788	NCOA1	P28482	MAPK1	S997	S999F	999	Missense	proximal	2	no	15.203	15.071	EPSD	TCGA;ICGC;COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q15788	NCOA1	P28482	MAPK1	S999	S999F	999	Missense	central	0	yes	14.126	0.000	EPSD	TCGA;ICGC;COSMIC	8.102	Loss
CMGC_MAPK_ERK1_MAPK1_ST	Q15788	NCOA1	P28482	MAPK1	S1006	S999F	999	Missense	distal	-7	no	12.901	12.881	EPSD	TCGA;ICGC;COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q15788	NCOA1	P28482	MAPK1	T1026	P1022A	1022	Missense	distal	-4	no	14.567	14.274	EPSD	TCGA;ICGC;COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q15788	NCOA1	P28482	MAPK1	T1026	S1033L	1033	Missense	distal	7	no	14.567	14.855	EPSD	TCGA;ICGC;COSMIC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q15788	NCOA1	P28482	MAPK1	T1026	A1031D	1031	Missense	distal	5	no	14.567	14.752	EPSD	TCGA;ICGC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q15788	NCOA1	P28482	MAPK1	S1033	M1036I	1036	Missense	distal	3	no	13.749	13.792	EPSD	TCGA;ICGC;COSMIC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q15788	NCOA1	P28482	MAPK1	S1033	P1034S	1034	Missense	proximal	1	no	13.749	4.354	EPSD	TCGA;ICGC;COSMIC	8.102	Loss
CMGC_MAPK_ERK1_MAPK1_ST	Q15788	NCOA1	P28482	MAPK1	S1033	S1033L	1033	Missense	central	0	yes	13.749	0.000	EPSD	TCGA;ICGC;COSMIC	8.102	Loss
CMGC_MAPK_ERK1_MAPK1_ST	Q15788	NCOA1	P28482	MAPK1	S1033	A1031D	1031	Missense	proximal	-2	no	13.749	13.594	EPSD	TCGA;ICGC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q15788	NCOA1	P28482	MAPK1	S1033	G1037D	1037	Missense	distal	4	no	13.749	13.701	EPSD	TCGA;ICGC;COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q15788	NCOA1	P28482	MAPK1	S1250	A1243P	1243	Missense	distal	-7	no	13.971	13.973	EPSD	TCGA;ICGC;COSMIC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q15788	NCOA1	P28482	MAPK1	S1250	P1251T	1251	Missense	proximal	1	no	13.971	5.472	EPSD	TCGA;ICGC;COSMIC	8.102	Loss
CMGC_MAPK_ERK1_MAPK1_ST	Q15788	NCOA1	P28482	MAPK1	T1271	S1275F	1275	Missense	distal	4	no	14.120	13.942	EPSD	TCGA;GDSC;CCLE	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q15788	NCOA1	P28482	MAPK1	T1271	Q1270K	1270	Missense	proximal	-1	no	14.120	14.174	EPSD	TCGA	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q15788	NCOA1	P28482	MAPK1	T1271	Q1270E	1270	Missense	proximal	-1	no	14.120	14.146	EPSD	TCGA;ICGC;COSMIC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q15788	NCOA1	P28482	MAPK1	T1271	S1266Y	1266	Missense	distal	-5	no	14.120	14.251	EPSD	TCGA;ICGC;COSMIC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q15788	NCOA1	P28482	MAPK1	S1279	S1275F	1275	Missense	distal	-4	no	14.789	14.528	EPSD	TCGA;GDSC;CCLE	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q15788	NCOA1	P28482	MAPK1	S1279	W1285L	1285	Missense	distal	6	no	14.789	15.413	EPSD	TCGA;ICGC;COSMIC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q15788	NCOA1	P28482	MAPK1	T1426	Q1430H	1430	Missense	distal	4	no	19.438	19.371	EPSD	TCGA	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P09917	ALOX5	P28482	MAPK1	S532	R533W	533	Missense	proximal	1	no	6.495	8.773	EPSD	TCGA;ICGC;COSMIC	8.102	Gain
CMGC_MAPK_ERK1_MAPK1_ST	P09917	ALOX5	P28482	MAPK1	S664	P669S	669	Missense	distal	5	no	16.483	16.501	PhosphoSitePlus	TCGA;COSMIC;GDSC;CCLE	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P09917	ALOX5	P28482	MAPK1	S664	D666H	666	Missense	proximal	2	no	16.483	16.369	PhosphoSitePlus	TCGA;COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P09917	ALOX5	P28482	MAPK1	S664	R667Q	667	Missense	distal	3	no	16.483	16.505	PhosphoSitePlus	TCGA;COSMIC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P09917	ALOX5	P28482	MAPK1	S664	R667W	667	Missense	distal	3	no	16.483	16.632	PhosphoSitePlus	TCGA;COSMIC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P15923	TCF3	P28482	MAPK1	S110	A107T	107	Missense	distal	-3	no	9.107	9.265	EPSD	TCGA;ICGC;COSMIC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P15923	TCF3	P28482	MAPK1	S110	R105Q	105	Missense	distal	-5	no	9.107	9.185	EPSD	TCGA;ICGC;COSMIC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P15923	TCF3	P28482	MAPK1	S134	S134N	134	Missense	central	0	yes	14.698	0.000	EPSD	TCGA;ICGC;COSMIC	8.102	Loss
CMGC_MAPK_ERK1_MAPK1_ST	P15923	TCF3	P28482	MAPK1	S139	S134N	134	Missense	distal	-5	no	18.181	18.132	EPSD	TCGA;ICGC;COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P15923	TCF3	P28482	MAPK1	T205	P201S	201	Missense	distal	-4	no	13.439	13.356	EPSD	TCGA;ICGC;COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P15923	TCF3	P28482	MAPK1	S208	P201S	201	Missense	distal	-7	no	9.363	9.359	EPSD	TCGA;ICGC;COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P15923	TCF3	P28482	MAPK1	T308	D315N	315	Missense	distal	7	no	13.017	13.003	EPSD	TCGA;ICGC;COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P15923	TCF3	P28482	MAPK1	S379	G376S	376	Missense	distal	-3	no	13.460	13.473	EPSD	TCGA;ICGC;COSMIC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P15923	TCF3	P28482	MAPK1	S529	P524S	524	Missense	distal	-5	no	15.759	15.833	EPSD	TCGA;ICGC;COSMIC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P15923	TCF3	P28482	MAPK1	S529	R525W	525	Missense	distal	-4	no	15.759	14.816	EPSD	TCGA;COSMIC;GDSC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q96RK0	CIC	P28482	MAPK1	S105	E104K	104	Missense	proximal	-1	no	16.034	16.062	EPSD	TCGA;COSMIC;GDSC;CCLE	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q96RK0	CIC	P28482	MAPK1	S191	N193Y	193	Missense	proximal	2	no	14.663	14.543	EPSD	TCGA;COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q96RK0	CIC	P28482	MAPK1	S191	E186Q	186	Missense	distal	-5	no	14.663	14.762	EPSD	TCGA;COSMIC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q96RK0	CIC	P28482	MAPK1	S191	G189E	189	Missense	proximal	-2	no	14.663	15.477	EPSD	TCGA;COSMIC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q96RK0	CIC	P28482	MAPK1	S285	S278N	278	Missense	distal	-7	no	8.461	8.463	EPSD	TCGA;COSMIC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q96RK0	CIC	P28482	MAPK1	T393	S387C	387	Missense	distal	-6	no	8.549	8.408	EPSD	TCGA;ICGC;COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q96RK0	CIC	P28482	MAPK1	S496	R492W	492	Missense	distal	-4	no	16.403	15.460	EPSD	TCGA;ICGC;COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q96RK0	CIC	P28482	MAPK1	S496	F495L	495	Missense	proximal	-1	no	16.403	16.433	EPSD	TCGA;ICGC;COSMIC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q96RK0	CIC	P28482	MAPK1	S496	S502F	502	Missense	distal	6	no	16.403	15.962	EPSD	TCGA;ICGC;COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q96RK0	CIC	P28482	MAPK1	S496	S501F	501	Missense	distal	5	no	16.403	16.206	EPSD	TCGA;ICGC;COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q96RK0	CIC	P28482	MAPK1	S496	R492Q	492	Missense	distal	-4	no	16.403	16.300	EPSD	TCGA;ICGC;COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q96RK0	CIC	P28482	MAPK1	S538	S543L	543	Missense	distal	5	no	12.538	12.307	EPSD	TCGA;ICGC;COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q96RK0	CIC	P28482	MAPK1	S545	S543L	543	Missense	proximal	-2	no	7.590	8.507	EPSD	TCGA;ICGC;COSMIC	8.102	Gain
CMGC_MAPK_ERK1_MAPK1_ST	Q96RK0	CIC	P28482	MAPK1	T583	A582P	582	Missense	proximal	-1	no	16.950	16.987	EPSD	TCGA;ICGC;COSMIC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q96RK0	CIC	P28482	MAPK1	T583	R589Q	589	Missense	distal	6	no	16.950	16.769	EPSD	TCGA;ICGC;COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q96RK0	CIC	P28482	MAPK1	T583	G580A	580	Missense	distal	-3	no	16.950	16.771	EPSD	TCGA;ICGC;COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q96RK0	CIC	P28482	MAPK1	T583	F590L	590	Missense	distal	7	no	16.950	16.891	EPSD	TCGA;ICGC;COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q96RK0	CIC	P28482	MAPK1	T583	R589W	589	Missense	distal	6	no	16.950	16.027	EPSD	TCGA;ICGC;COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q96RK0	CIC	P28482	MAPK1	T583	P576S	576	Missense	distal	-7	no	16.950	16.946	EPSD	TCGA;ICGC;COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q96RK0	CIC	P28482	MAPK1	S700	E698K	698	Missense	proximal	-2	no	12.565	12.525	EPSD	TCGA;ICGC;COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q96RK0	CIC	P28482	MAPK1	T704	E698K	698	Missense	distal	-6	no	8.279	8.253	EPSD	TCGA;ICGC;COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q96RK0	CIC	P28482	MAPK1	T704	R708M	708	Missense	distal	4	no	8.279	8.114	EPSD	TCGA;ICGC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q96RK0	CIC	P28482	MAPK1	S739	H743L	743	Missense	distal	4	no	12.857	12.911	EPSD	TCGA;ICGC;COSMIC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q96RK0	CIC	P28482	MAPK1	S739	P742L	742	Missense	distal	3	no	12.857	12.946	EPSD	TCGA;ICGC;COSMIC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q96RK0	CIC	P28482	MAPK1	S739	A737T	737	Missense	proximal	-2	no	12.857	13.304	EPSD	TCGA;ICGC;COSMIC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q96RK0	CIC	P28482	MAPK1	S739	A746V	746	Missense	distal	7	no	12.857	12.958	EPSD	TCGA;ICGC;COSMIC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q96RK0	CIC	P28482	MAPK1	S894	A900P	900	Missense	distal	6	no	8.842	9.138	EPSD	TCGA;ICGC;COSMIC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q96RK0	CIC	P28482	MAPK1	S894	S891P	891	Missense	distal	-3	no	8.842	9.019	EPSD	TCGA;ICGC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q96RK0	CIC	P28482	MAPK1	S904	P909Q	909	Missense	distal	5	no	15.460	15.340	EPSD	TCGA;ICGC;COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q96RK0	CIC	P28482	MAPK1	S904	A900P	900	Missense	distal	-4	no	15.460	15.753	EPSD	TCGA;ICGC;COSMIC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q96RK0	CIC	P28482	MAPK1	S904	P910L	910	Missense	distal	6	no	15.460	15.054	EPSD	TCGA;ICGC;COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q96RK0	CIC	P28482	MAPK1	S904	P905L	905	Missense	proximal	1	no	15.460	6.651	EPSD	TCGA;ICGC;COSMIC	8.102	Loss
CMGC_MAPK_ERK1_MAPK1_ST	Q96RK0	CIC	P28482	MAPK1	S914	P909Q	909	Missense	distal	-5	no	8.312	8.437	EPSD	TCGA;ICGC;COSMIC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q96RK0	CIC	P28482	MAPK1	S914	P910L	910	Missense	distal	-4	no	8.312	8.008	EPSD	TCGA;ICGC;COSMIC	8.102	Loss
CMGC_MAPK_ERK1_MAPK1_ST	Q96RK0	CIC	P28482	MAPK1	S946	S950L	950	Missense	distal	4	no	15.138	15.028	EPSD	TCGA;ICGC;COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q96RK0	CIC	P28482	MAPK1	S946	P947S	947	Missense	proximal	1	no	15.138	5.743	EPSD	TCGA;ICGC;COSMIC	8.102	Loss
CMGC_MAPK_ERK1_MAPK1_ST	Q96RK0	CIC	P28482	MAPK1	S982	V978M	978	Missense	distal	-4	no	16.761	16.650	EPSD	TCGA;ICGC;COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q96RK0	CIC	P28482	MAPK1	S1173	P1177L	1177	Missense	distal	4	no	14.359	14.239	EPSD	TCGA;ICGC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q96RK0	CIC	P28482	MAPK1	S1173	R1171Q	1171	Missense	proximal	-2	no	14.359	13.184	EPSD	TCGA;COSMIC;GDSC;CCLE	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q96RK0	CIC	P28482	MAPK1	S1191	V1189M	1189	Missense	proximal	-2	no	8.179	6.037	EPSD	TCGA;COSMIC	8.102	Loss
CMGC_MAPK_ERK1_MAPK1_ST	Q96RK0	CIC	P28482	MAPK1	S1191	V1189L	1189	Missense	proximal	-2	no	8.179	8.134	EPSD	TCGA;ICGC;COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q96RK0	CIC	P28482	MAPK1	S1191	S1191F	1191	Missense	central	0	yes	8.179	0.000	EPSD	TCGA;ICGC;COSMIC	8.102	Loss
CMGC_MAPK_ERK1_MAPK1_ST	Q96RK0	CIC	P28482	MAPK1	T1228	E1224Q	1224	Missense	distal	-4	no	14.763	14.599	EPSD	TCGA;ICGC;COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q96RK0	CIC	P28482	MAPK1	T1238	E1237K	1237	Missense	proximal	-1	no	8.879	8.907	EPSD	TCGA;COSMIC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q96RK0	CIC	P28482	MAPK1	T1238	A1243T	1243	Missense	distal	5	no	8.879	8.965	EPSD	TCGA	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q96RK0	CIC	P28482	MAPK1	T1240	E1237K	1237	Missense	distal	-3	no	13.602	13.524	EPSD	TCGA;COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q96RK0	CIC	P28482	MAPK1	T1240	A1243T	1243	Missense	distal	3	no	13.602	13.585	EPSD	TCGA	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q96RK0	CIC	P28482	MAPK1	S1246	A1243T	1243	Missense	distal	-3	no	16.144	16.302	EPSD	TCGA	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q96RK0	CIC	P28482	MAPK1	T1291	S1294R	1294	Missense	distal	3	no	17.146	17.123	EPSD	TCGA;COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q96RK0	CIC	P28482	MAPK1	S1294	S1294R	1294	Missense	central	0	yes	18.874	0.000	EPSD	TCGA;COSMIC	8.102	Loss
CMGC_MAPK_ERK1_MAPK1_ST	Q96RK0	CIC	P28482	MAPK1	T1318	R1321H	1321	Missense	distal	3	no	13.559	13.602	EPSD	TCGA;COSMIC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q96RK0	CIC	P28482	MAPK1	T1318	D1317E	1317	Missense	proximal	-1	no	13.559	13.599	EPSD	TCGA;ICGC;COSMIC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q96RK0	CIC	P28482	MAPK1	T1318	K1322Q	1322	Missense	distal	4	no	13.559	13.474	EPSD	TCGA;ICGC;COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q96RK0	CIC	P28482	MAPK1	S1373	S1378F	1378	Missense	distal	5	no	13.043	12.846	EPSD	TCGA;COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q96RK0	CIC	P28482	MAPK1	S1373	P1374L	1374	Missense	proximal	1	no	13.043	4.233	EPSD	TCGA;COSMIC	8.102	Loss
CMGC_MAPK_ERK1_MAPK1_ST	Q96RK0	CIC	P28482	MAPK1	S1382	S1378F	1378	Missense	distal	-4	no	14.115	13.854	EPSD	TCGA;COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q96RK0	CIC	P28482	MAPK1	S1382	R1384W	1384	Missense	proximal	2	no	14.115	13.746	EPSD	TCGA;ICGC;COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q96RK0	CIC	P28482	MAPK1	S1409	R1412L	1412	Missense	distal	3	no	17.236	17.279	PhosphoSitePlus;EPSD	TCGA;COSMIC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q96RK0	CIC	P28482	MAPK1	S1409	S1409L	1409	Missense	central	0	yes	17.236	0.000	PhosphoSitePlus;EPSD	TCGA;ICGC;COSMIC	8.102	Loss
CMGC_MAPK_ERK1_MAPK1_ST	Q96RK0	CIC	P28482	MAPK1	S1409	A1403T	1403	Missense	distal	-6	no	17.236	17.225	PhosphoSitePlus;EPSD	TCGA;COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q96RK0	CIC	P28482	MAPK1	T1426	S1429I	1429	Missense	distal	3	no	14.873	14.932	EPSD	TCGA;ICGC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q96RK0	CIC	P28482	MAPK1	S1429	S1429I	1429	Missense	central	0	yes	10.046	0.000	EPSD	TCGA;ICGC	8.102	Loss
CMGC_MAPK_ERK1_MAPK1_ST	Q96RK0	CIC	P28482	MAPK1	S1429	D1435G	1435	Missense	distal	6	no	10.046	10.015	EPSD	TCGA;ICGC;COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P14598	NCF1	P28482	MAPK1	T138	K135N	135	Missense	distal	-3	no	10.329	10.425	EPSD	TCGA;ICGC;COSMIC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q92793	CREBBP	P28482	MAPK1	S23	D29Y	29	Missense	distal	6	no	9.036	8.463	EPSD	TCGA;ICGC;COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q92793	CREBBP	P28482	MAPK1	S27	S32L	32	Missense	distal	5	no	8.129	7.897	EPSD	TCGA;ICGC;COSMIC	8.102	Loss
CMGC_MAPK_ERK1_MAPK1_ST	Q92793	CREBBP	P28482	MAPK1	S27	D29Y	29	Missense	proximal	2	no	8.129	7.949	EPSD	TCGA;ICGC;COSMIC	8.102	Loss
CMGC_MAPK_ERK1_MAPK1_ST	Q92793	CREBBP	P28482	MAPK1	S93	G98C	98	Missense	distal	5	no	13.467	13.087	PhosphoSitePlus	TCGA;ICGC;COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q92793	CREBBP	P28482	MAPK1	S121	G119V	119	Missense	proximal	-2	no	12.427	13.748	EPSD	TCGA;ICGC;COSMIC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q92793	CREBBP	P28482	MAPK1	T309	T312A	312	Missense	distal	3	no	8.161	8.178	EPSD	TCGA;ICGC;COSMIC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q92793	CREBBP	P28482	MAPK1	T309	V304I	304	Missense	distal	-5	no	8.161	8.274	EPSD	TCGA;ICGC;COSMIC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q92793	CREBBP	P28482	MAPK1	T309	P311S	311	Missense	proximal	2	no	8.161	8.134	EPSD	TCGA;ICGC;COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q92793	CREBBP	P28482	MAPK1	S451	I457V	457	Missense	distal	6	no	7.663	8.116	EPSD	TCGA;COSMIC	8.102	Gain
CMGC_MAPK_ERK1_MAPK1_ST	Q92793	CREBBP	P28482	MAPK1	S745	M739I	739	Missense	distal	-6	no	16.277	16.234	EPSD	TCGA	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q92793	CREBBP	P28482	MAPK1	S745	P746S	746	Missense	proximal	1	no	16.277	6.882	EPSD	TCGA;COSMIC	8.102	Loss
CMGC_MAPK_ERK1_MAPK1_ST	Q92793	CREBBP	P28482	MAPK1	S745	V751I	751	Missense	distal	6	no	16.277	15.825	EPSD	TCGA;COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q92793	CREBBP	P28482	MAPK1	S745	R742C	742	Missense	distal	-3	no	16.277	15.593	EPSD	TCGA;COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q92793	CREBBP	P28482	MAPK1	S1019	E1012K	1012	Missense	distal	-7	no	9.150	9.143	EPSD	TCGA;COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q92793	CREBBP	P28482	MAPK1	S1019	E1024D	1024	Missense	distal	5	no	9.150	9.219	EPSD	TCGA	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q92793	CREBBP	P28482	MAPK1	S1019	E1023K	1023	Missense	distal	4	no	9.150	9.165	EPSD	TCGA;COSMIC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q92793	CREBBP	P28482	MAPK1	S1019	S1013P	1013	Missense	distal	-6	no	9.150	9.176	EPSD	TCGA;COSMIC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q92793	CREBBP	P28482	MAPK1	S1763	G1757C	1757	Missense	distal	-6	no	15.448	15.324	EPSD	TCGA;COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q92793	CREBBP	P28482	MAPK1	S1763	R1768C	1768	Missense	distal	5	no	15.448	15.017	EPSD	TCGA;COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q92793	CREBBP	P28482	MAPK1	S1763	S1767L	1767	Missense	distal	4	no	15.448	15.338	EPSD	TCGA;COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q92793	CREBBP	P28482	MAPK1	S1763	E1766K	1766	Missense	distal	3	no	15.448	15.455	EPSD	TCGA;COSMIC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q92793	CREBBP	P28482	MAPK1	S1884	S1881N	1881	Missense	distal	-3	no	14.906	14.921	EPSD	TCGA	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q92793	CREBBP	P28482	MAPK1	S1887	S1881N	1881	Missense	distal	-6	no	9.839	9.842	EPSD	TCGA	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q92793	CREBBP	P28482	MAPK1	T1899	P1900A	1900	Missense	proximal	1	no	17.247	9.617	EPSD	TCGA;COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q92793	CREBBP	P28482	MAPK1	T1899	P1903L	1903	Missense	distal	4	no	17.247	17.127	EPSD	TCGA	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q92793	CREBBP	P28482	MAPK1	T1990	Q1994H	1994	Missense	distal	4	no	12.024	11.957	EPSD	TCGA;COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q92793	CREBBP	P28482	MAPK1	T1990	R1985C	1985	Missense	distal	-5	no	12.024	12.253	EPSD	TCGA;COSMIC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q92793	CREBBP	P28482	MAPK1	T1990	A1996T	1996	Missense	distal	6	no	12.024	12.110	EPSD	TCGA;COSMIC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q92793	CREBBP	P28482	MAPK1	S1993	Q1994H	1994	Missense	proximal	1	no	8.530	9.200	EPSD	TCGA;COSMIC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q92793	CREBBP	P28482	MAPK1	S1993	A1996T	1996	Missense	distal	3	no	8.530	8.514	EPSD	TCGA;COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q92793	CREBBP	P28482	MAPK1	S2063	A2066T	2066	Missense	distal	3	no	13.590	13.574	EPSD	TCGA;COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q92793	CREBBP	P28482	MAPK1	S2076	S2079F	2079	Missense	distal	3	no	13.145	13.207	EPSD	TCGA;COSMIC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q92793	CREBBP	P28482	MAPK1	S2076	R2072W	2072	Missense	distal	-4	no	13.145	12.202	EPSD	TCGA;COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q92793	CREBBP	P28482	MAPK1	S2076	P2077S	2077	Missense	proximal	1	no	13.145	3.750	EPSD	TCGA	8.102	Loss
CMGC_MAPK_ERK1_MAPK1_ST	Q92793	CREBBP	P28482	MAPK1	S2076	R2072Q	2072	Missense	distal	-4	no	13.145	13.042	EPSD	TCGA;COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q92793	CREBBP	P28482	MAPK1	S2078	S2079F	2079	Missense	proximal	1	no	5.689	8.514	EPSD	TCGA;COSMIC	8.102	Gain
CMGC_MAPK_ERK1_MAPK1_ST	Q92793	CREBBP	P28482	MAPK1	S2079	S2079F	2079	Missense	central	0	yes	16.458	0.000	EPSD	TCGA;COSMIC	8.102	Loss
CMGC_MAPK_ERK1_MAPK1_ST	Q92793	CREBBP	P28482	MAPK1	S2079	R2072W	2072	Missense	distal	-7	no	16.458	16.407	EPSD	TCGA;COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q92793	CREBBP	P28482	MAPK1	S2079	P2077S	2077	Missense	proximal	-2	no	16.458	13.624	EPSD	TCGA	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q92793	CREBBP	P28482	MAPK1	S2079	R2072Q	2072	Missense	distal	-7	no	16.458	16.466	EPSD	TCGA;COSMIC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q92793	CREBBP	P28482	MAPK1	S2307	M2301I	2301	Missense	distal	-6	no	14.864	14.820	EPSD	TCGA;COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q92793	CREBBP	P28482	MAPK1	S2315	S2315C	2315	Missense	central	0	yes	15.289	0.000	EPSD	TCGA;COSMIC	8.102	Loss
CMGC_MAPK_ERK1_MAPK1_ST	Q92793	CREBBP	P28482	MAPK1	S2315	Q2317K	2317	Missense	proximal	2	no	15.289	15.400	EPSD	TCGA;COSMIC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q92793	CREBBP	P28482	MAPK1	S2345	S2340N	2340	Missense	distal	-5	no	13.537	13.488	EPSD	TCGA	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q92793	CREBBP	P28482	MAPK1	S2345	R2344Q	2344	Missense	proximal	-1	no	13.537	13.515	EPSD	TCGA;COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q92793	CREBBP	P28482	MAPK1	S2345	R2344W	2344	Missense	proximal	-1	no	13.537	13.435	EPSD	TCGA;COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q92793	CREBBP	P28482	MAPK1	S2345	A2347V	2347	Missense	proximal	2	no	13.537	13.613	EPSD	TCGA;COSMIC;GDSC;CCLE	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q92793	CREBBP	P28482	MAPK1	S2345	S2338F	2338	Missense	distal	-7	no	13.537	13.517	EPSD	TCGA	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q92793	CREBBP	P28482	MAPK1	S2345	S2351F	2351	Missense	distal	6	no	13.537	13.096	EPSD	TCGA;COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q92793	CREBBP	P28482	MAPK1	S2351	R2344Q	2344	Missense	distal	-7	no	16.238	16.246	EPSD	TCGA;COSMIC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q92793	CREBBP	P28482	MAPK1	S2351	R2353L	2353	Missense	proximal	2	no	16.238	15.977	EPSD	TCGA;COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q92793	CREBBP	P28482	MAPK1	S2351	S2356F	2356	Missense	distal	5	no	16.238	16.041	EPSD	TCGA;COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q92793	CREBBP	P28482	MAPK1	S2351	R2344W	2344	Missense	distal	-7	no	16.238	16.188	EPSD	TCGA;COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q92793	CREBBP	P28482	MAPK1	S2351	A2347V	2347	Missense	distal	-4	no	16.238	16.178	EPSD	TCGA;COSMIC;GDSC;CCLE	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q92793	CREBBP	P28482	MAPK1	S2351	S2351F	2351	Missense	central	0	yes	16.238	0.000	EPSD	TCGA;COSMIC	8.102	Loss
CMGC_MAPK_ERK1_MAPK1_ST	Q92793	CREBBP	P28482	MAPK1	S2362	S2356F	2356	Missense	distal	-6	no	13.050	12.966	EPSD	TCGA;COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q92793	CREBBP	P28482	MAPK1	S2364	P2371L	2371	Missense	distal	7	no	14.289	14.588	EPSD	TCGA;COSMIC;GDSC;CCLE	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q92793	CREBBP	P28482	MAPK1	S2372	S2372L	2372	Missense	central	0	yes	15.012	0.000	EPSD	TCGA;COSMIC	8.102	Loss
CMGC_MAPK_ERK1_MAPK1_ST	Q92793	CREBBP	P28482	MAPK1	S2372	P2371L	2371	Missense	proximal	-1	no	15.012	14.952	EPSD	TCGA;COSMIC;GDSC;CCLE	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q92793	CREBBP	P28482	MAPK1	S2377	G2381V	2381	Missense	distal	4	no	13.072	13.022	EPSD	TCGA;COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q92793	CREBBP	P28482	MAPK1	S2377	G2381C	2381	Missense	distal	4	no	13.072	12.840	EPSD	TCGA;COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q92793	CREBBP	P28482	MAPK1	S2377	S2372L	2372	Missense	distal	-5	no	13.072	13.147	EPSD	TCGA;COSMIC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q92793	CREBBP	P28482	MAPK1	S2377	H2384Q	2384	Missense	distal	7	no	13.072	12.968	EPSD	TCGA;COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q92793	CREBBP	P28482	MAPK1	S2377	S2382F	2382	Missense	distal	5	no	13.072	12.875	EPSD	TCGA;COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q92793	CREBBP	P28482	MAPK1	S2377	P2371L	2371	Missense	distal	-6	no	13.072	12.980	EPSD	TCGA;COSMIC;GDSC;CCLE	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q92793	CREBBP	P28482	MAPK1	S2382	G2381V	2381	Missense	proximal	-1	no	13.983	14.012	EPSD	TCGA;COSMIC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q92793	CREBBP	P28482	MAPK1	S2382	G2381C	2381	Missense	proximal	-1	no	13.983	13.916	EPSD	TCGA;COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q92793	CREBBP	P28482	MAPK1	S2382	H2384Q	2384	Missense	proximal	2	no	13.983	13.935	EPSD	TCGA;COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q92793	CREBBP	P28482	MAPK1	S2382	P2385L	2385	Missense	distal	3	no	13.983	14.073	EPSD	TCGA;COSMIC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q92793	CREBBP	P28482	MAPK1	S2382	S2382F	2382	Missense	central	0	yes	13.983	0.000	EPSD	TCGA;COSMIC	8.102	Loss
CMGC_MAPK_ERK1_MAPK1_ST	Q92793	CREBBP	P28482	MAPK1	S2425	D2429N	2429	Missense	distal	4	no	9.116	9.175	EPSD	TCGA;COSMIC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q96RS0	TGS1	P28482	MAPK1	T168	L171R	171	Missense	distal	3	no	9.063	9.019	EPSD	TCGA;ICGC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q96RS0	TGS1	P28482	MAPK1	S189	P182S	182	Missense	distal	-7	no	13.150	13.145	EPSD	TCGA;ICGC;COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q96RS0	TGS1	P28482	MAPK1	S294	P296A	296	Missense	proximal	2	no	9.516	9.386	EPSD	TCGA;ICGC;COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q96RS0	TGS1	P28482	MAPK1	S294	P296S	296	Missense	proximal	2	no	9.516	9.488	EPSD	TCGA;ICGC;COSMIC;GDSC;CCLE	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q96RS0	TGS1	P28482	MAPK1	S298	P296A	296	Missense	proximal	-2	no	18.074	14.928	PhosphoSitePlus	TCGA;ICGC;COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q96RS0	TGS1	P28482	MAPK1	S298	D303G	303	Missense	distal	5	no	18.074	18.030	PhosphoSitePlus	TCGA;ICGC;COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q96RS0	TGS1	P28482	MAPK1	S298	P296S	296	Missense	proximal	-2	no	18.074	15.240	PhosphoSitePlus	TCGA;ICGC;COSMIC;GDSC;CCLE	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q96RS0	TGS1	P28482	MAPK1	S438	D431G	431	Missense	distal	-7	no	8.666	8.651	EPSD	TCGA;ICGC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q96RS0	TGS1	P28482	MAPK1	S753	K756R	756	Missense	distal	3	no	8.145	8.193	EPSD	TCGA;ICGC;COSMIC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q96RS0	TGS1	P28482	MAPK1	S753	D747Y	747	Missense	distal	-6	no	8.145	7.982	EPSD	TCGA;ICGC	8.102	Loss
CMGC_MAPK_ERK1_MAPK1_ST	Q96RS0	TGS1	P28482	MAPK1	S784	D786H	786	Missense	proximal	2	no	12.825	12.711	EPSD	TCGA;ICGC;COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q96RS0	TGS1	P28482	MAPK1	S784	I790M	790	Missense	distal	6	no	12.825	13.059	EPSD	TCGA;COSMIC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q96RS0	TGS1	P28482	MAPK1	S784	S784Y	784	Missense	central	0	yes	12.825	0.000	EPSD	TCGA;ICGC;COSMIC;GDSC;CCLE	8.102	Loss
CMGC_MAPK_ERK1_MAPK1_ST	Q01196	RUNX1	P28482	MAPK1	S212	P216H	216	Missense	distal	4	no	15.977	15.802	EPSD	TCGA	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q01196	RUNX1	P28482	MAPK1	T219	P216H	216	Missense	distal	-3	no	13.327	12.978	EPSD	TCGA	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q01196	RUNX1	P28482	MAPK1	S435	A440T	440	Missense	distal	5	no	17.032	17.118	EPSD	TCGA;ICGC;COSMIC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q01196	RUNX1	P28482	MAPK1	S442	A440T	440	Missense	proximal	-2	no	7.944	8.391	EPSD	TCGA;ICGC;COSMIC	8.102	Gain
CMGC_MAPK_ERK1_MAPK1_ST	Q01860	POU5F1	P28482	MAPK1	S111	P112R	112	Missense	proximal	1	no	12.790	3.136	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	8.102	Loss
CMGC_MAPK_ERK1_MAPK1_ST	Q01860	POU5F1	P28482	MAPK1	S111	S111F	111	Missense	central	0	yes	12.790	0.000	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	8.102	Loss
CMGC_MAPK_ERK1_MAPK1_ST	Q01860	POU5F1	P28482	MAPK1	S111	P112L	112	Missense	proximal	1	no	12.790	3.980	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	8.102	Loss
CMGC_MAPK_ERK1_MAPK1_ST	Q01860	POU5F1	P28482	MAPK1	S111	V117I	117	Missense	distal	6	no	12.790	12.338	EPSD;PhosphoSitePlus	TCGA;ICGC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q01860	POU5F1	P28482	MAPK1	T118	P112R	112	Missense	distal	-6	no	14.457	14.465	PhosphoSitePlus;EPSD	TCGA;ICGC;COSMIC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q01860	POU5F1	P28482	MAPK1	T118	S111F	111	Missense	distal	-7	no	14.457	14.437	PhosphoSitePlus;EPSD	TCGA;ICGC;COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q01860	POU5F1	P28482	MAPK1	T118	P112L	112	Missense	distal	-6	no	14.457	14.365	PhosphoSitePlus;EPSD	TCGA;ICGC;COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q01860	POU5F1	P28482	MAPK1	T118	V117I	117	Missense	proximal	-1	no	14.457	14.417	PhosphoSitePlus;EPSD	TCGA;ICGC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q01860	POU5F1	P28482	MAPK1	T118	P119H	119	Missense	proximal	1	no	14.457	6.633	PhosphoSitePlus;EPSD	TCGA;ICGC;COSMIC	8.102	Loss
CMGC_MAPK_ERK1_MAPK1_ST	P49795	RGS19	P28482	MAPK1	S24	D27Y	27	Missense	distal	3	no	8.902	8.942	EPSD	TCGA;ICGC;COSMIC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P49795	RGS19	P28482	MAPK1	S24	R19Q	19	Missense	distal	-5	no	8.902	8.979	EPSD	TCGA;ICGC;COSMIC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P49795	RGS19	P28482	MAPK1	S25	D27Y	27	Missense	proximal	2	no	8.730	8.550	EPSD	TCGA;ICGC;COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P49795	RGS19	P28482	MAPK1	S25	R19Q	19	Missense	distal	-6	no	8.730	8.706	EPSD	TCGA;ICGC;COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P49795	RGS19	P28482	MAPK1	S25	A32T	32	Missense	distal	7	no	8.730	8.701	EPSD	TCGA;ICGC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P49795	RGS19	P28482	MAPK1	T28	D27Y	27	Missense	proximal	-1	no	8.654	8.634	EPSD	TCGA;ICGC;COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P49795	RGS19	P28482	MAPK1	T28	A32T	32	Missense	distal	4	no	8.654	8.634	EPSD	TCGA;ICGC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P49795	RGS19	P28482	MAPK1	S30	D27Y	27	Missense	distal	-3	no	15.979	15.662	EPSD	TCGA;ICGC;COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P49795	RGS19	P28482	MAPK1	S30	A32T	32	Missense	proximal	2	no	15.979	16.058	EPSD	TCGA;ICGC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P49795	RGS19	P28482	MAPK1	T78	E83K	83	Missense	distal	5	no	13.115	13.056	EPSD	TCGA;ICGC;COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P49795	RGS19	P28482	MAPK1	S80	E83K	83	Missense	distal	3	no	14.355	14.362	EPSD	TCGA;ICGC;COSMIC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P49795	RGS19	P28482	MAPK1	S97	G100E	100	Missense	distal	3	no	11.333	11.240	EPSD	TCGA;ICGC;COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P49795	RGS19	P28482	MAPK1	S97	A99V	99	Missense	proximal	2	no	11.333	11.409	EPSD	TCGA;ICGC;COSMIC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q8NHW3	MAFA	P28482	MAPK1	S14	A9D	9	Missense	distal	-5	no	18.324	18.270	PhosphoSitePlus;EPSD	TCGA;ICGC;COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q9BUB5	MKNK1	P28482	MAPK1	S221	L218W	218	Missense	distal	-3	no	11.453	11.119	EPSD	TCGA;COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q9BUB5	MKNK1	P28482	MAPK1	T255	E261K	261	Missense	distal	6	no	16.196	16.219	PhosphoSitePlus	TCGA;COSMIC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q9BUB5	MKNK1	P28482	MAPK1	T255	S259C	259	Missense	distal	4	no	16.196	15.914	PhosphoSitePlus	TCGA;COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q9BUB5	MKNK1	P28482	MAPK1	T255	A260T	260	Missense	distal	5	no	16.196	16.282	PhosphoSitePlus	TCGA	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q9BUB5	MKNK1	P28482	MAPK1	T385	P379L	379	Missense	distal	-6	no	13.507	13.415	EPSD	TCGA;ICGC;COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q9BUB5	MKNK1	P28482	MAPK1	T385	A378T	378	Missense	distal	-7	no	13.507	13.492	EPSD	TCGA;ICGC;COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q9BUB5	MKNK1	P28482	MAPK1	S437	P439S	439	Missense	proximal	2	no	14.974	14.947	EPSD	TCGA;COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q9BUB5	MKNK1	P28482	MAPK1	S437	R443C	443	Missense	distal	6	no	14.974	14.214	EPSD	TCGA;COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q9BUB5	MKNK1	P28482	MAPK1	S437	S437F	437	Missense	central	0	yes	14.974	0.000	EPSD	TCGA;COSMIC	8.102	Loss
CMGC_MAPK_ERK1_MAPK1_ST	Q9BUB5	MKNK1	P28482	MAPK1	S460	D458G	458	Missense	proximal	-2	no	16.116	16.224	EPSD	TCGA	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q9BUB5	MKNK1	P28482	MAPK1	T463	D458G	458	Missense	distal	-5	no	8.107	8.104	EPSD	TCGA	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q96FF9	CDCA5	P28482	MAPK1	S21	S15C	15	Missense	distal	-6	no	16.770	16.630	EPSD	TCGA;ICGC;COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q96FF9	CDCA5	P28482	MAPK1	S75	S75L	75	Missense	central	0	yes	15.275	0.000	EPSD	TCGA;ICGC;COSMIC	8.102	Loss
CMGC_MAPK_ERK1_MAPK1_ST	Q96FF9	CDCA5	P28482	MAPK1	S79	S75L	75	Missense	distal	-4	no	13.946	13.726	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q96FF9	CDCA5	P28482	MAPK1	T111	P116H	116	Missense	distal	5	no	16.339	16.212	EPSD	TCGA;ICGC;COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q96FF9	CDCA5	P28482	MAPK1	T111	V108I	108	Missense	distal	-3	no	16.339	16.205	EPSD	TCGA;ICGC;COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q96FF9	CDCA5	P28482	MAPK1	S114	P116H	116	Missense	proximal	2	no	9.833	9.703	EPSD	TCGA;ICGC;COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q96FF9	CDCA5	P28482	MAPK1	S114	V108I	108	Missense	distal	-6	no	9.833	9.791	EPSD	TCGA;ICGC;COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q96FF9	CDCA5	P28482	MAPK1	T115	P116H	116	Missense	proximal	1	no	12.745	4.922	EPSD	TCGA;ICGC;COSMIC	8.102	Loss
CMGC_MAPK_ERK1_MAPK1_ST	Q96FF9	CDCA5	P28482	MAPK1	T115	V108I	108	Missense	distal	-7	no	12.745	12.732	EPSD	TCGA;ICGC;COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q96FF9	CDCA5	P28482	MAPK1	T159	S156C	156	Missense	distal	-3	no	11.368	10.842	EPSD	TCGA;ICGC;COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q96FF9	CDCA5	P28482	MAPK1	T159	S158F	158	Missense	proximal	-1	no	11.368	11.322	EPSD	TCGA;ICGC;COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q96FF9	CDCA5	P28482	MAPK1	S209	G207V	207	Missense	proximal	-2	no	12.164	13.486	PhosphoSitePlus;EPSD	TCGA;ICGC;COSMIC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q96FF9	CDCA5	P28482	MAPK1	S209	P212L	212	Missense	distal	3	no	12.164	12.254	PhosphoSitePlus;EPSD	TCGA;ICGC;COSMIC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q96FF9	CDCA5	P28482	MAPK1	S209	P211L	211	Missense	proximal	2	no	12.164	12.017	PhosphoSitePlus;EPSD	TCGA;ICGC;COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q96FF9	CDCA5	P28482	MAPK1	S209	E213D	213	Missense	distal	4	no	12.164	12.094	PhosphoSitePlus;EPSD	TCGA;ICGC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q13625	TP53BP2	P28482	MAPK1	S471	A468T	468	Missense	distal	-3	no	10.978	11.136	EPSD	TCGA;ICGC;COSMIC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q13625	TP53BP2	P28482	MAPK1	S827	S827C	827	Missense	central	0	yes	12.330	0.000	PhosphoSitePlus	TCGA;ICGC;COSMIC	8.102	Loss
CMGC_MAPK_ERK1_MAPK1_ST	P49137	MAPKAPK2	P28482	MAPK1	T25	T25P	25	Missense	central	0	yes	18.005	0.000	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	8.102	Loss
CMGC_MAPK_ERK1_MAPK1_ST	P49137	MAPKAPK2	P28482	MAPK1	S272	R278C	278	Missense	distal	6	no	15.974	15.214	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P49137	MAPKAPK2	P28482	MAPK1	S272	P273L	273	Missense	proximal	1	no	15.974	7.164	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	8.102	Loss
CMGC_MAPK_ERK1_MAPK1_ST	P49137	MAPKAPK2	P28482	MAPK1	T334	S339N	339	Missense	distal	5	no	15.495	15.423	EPSD;PhosphoSitePlus	TCGA;ICGC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q5JQC9	AKAP4	P28482	MAPK1	S19	S19R	19	Missense	central	0	yes	9.228	0.000	EPSD	TCGA	8.102	Loss
CMGC_MAPK_ERK1_MAPK1_ST	Q5JQC9	AKAP4	P28482	MAPK1	S19	C24Y	24	Missense	distal	5	no	9.228	9.339	EPSD	TCGA	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q5JQC9	AKAP4	P28482	MAPK1	S19	R18H	18	Missense	proximal	-1	no	9.228	9.204	EPSD	TCGA;COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q5JQC9	AKAP4	P28482	MAPK1	S19	D13N	13	Missense	distal	-6	no	9.228	9.182	EPSD	TCGA;COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q5JQC9	AKAP4	P28482	MAPK1	S19	D12N	12	Missense	distal	-7	no	9.228	9.229	EPSD	TCGA;COSMIC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q5JQC9	AKAP4	P28482	MAPK1	S130	G124C	124	Missense	distal	-6	no	11.858	11.734	EPSD	TCGA	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q5JQC9	AKAP4	P28482	MAPK1	S130	S130R	130	Missense	central	0	yes	11.858	0.000	EPSD	TCGA;COSMIC	8.102	Loss
CMGC_MAPK_ERK1_MAPK1_ST	Q5JQC9	AKAP4	P28482	MAPK1	S190	P194S	194	Missense	distal	4	no	14.195	14.184	EPSD	TCGA;COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q5JQC9	AKAP4	P28482	MAPK1	S190	N188D	188	Missense	proximal	-2	no	14.195	13.713	EPSD	TCGA;COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q5JQC9	AKAP4	P28482	MAPK1	S200	S207F	207	Missense	distal	7	no	7.853	8.201	EPSD	TCGA;COSMIC	8.102	Gain
CMGC_MAPK_ERK1_MAPK1_ST	Q5JQC9	AKAP4	P28482	MAPK1	T201	P194S	194	Missense	distal	-7	no	8.986	8.982	EPSD	TCGA;COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q5JQC9	AKAP4	P28482	MAPK1	T201	A204S	204	Missense	distal	3	no	8.986	8.977	EPSD	TCGA;COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q5JQC9	AKAP4	P28482	MAPK1	T201	Q202H	202	Missense	proximal	1	no	8.986	9.656	EPSD	TCGA;COSMIC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q5JQC9	AKAP4	P28482	MAPK1	T201	S207F	207	Missense	distal	6	no	8.986	8.546	EPSD	TCGA;COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q5JQC9	AKAP4	P28482	MAPK1	S207	A204S	204	Missense	distal	-3	no	15.036	15.227	EPSD	TCGA;COSMIC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q5JQC9	AKAP4	P28482	MAPK1	S207	S207F	207	Missense	central	0	yes	15.036	0.000	EPSD	TCGA;COSMIC	8.102	Loss
CMGC_MAPK_ERK1_MAPK1_ST	Q5JQC9	AKAP4	P28482	MAPK1	S207	D209E	209	Missense	proximal	2	no	15.036	14.985	EPSD	TCGA;COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q5JQC9	AKAP4	P28482	MAPK1	S207	S213Y	213	Missense	distal	6	no	15.036	14.418	EPSD	TCGA;COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q5JQC9	AKAP4	P28482	MAPK1	S207	E211D	211	Missense	distal	4	no	15.036	14.966	EPSD	TCGA	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q5JQC9	AKAP4	P28482	MAPK1	S254	N257K	257	Missense	distal	3	no	14.098	14.104	EPSD	TCGA;COSMIC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q5JQC9	AKAP4	P28482	MAPK1	S254	P255S	255	Missense	proximal	1	no	14.098	4.703	EPSD	TCGA;COSMIC	8.102	Loss
CMGC_MAPK_ERK1_MAPK1_ST	Q5JQC9	AKAP4	P28482	MAPK1	S254	C252Y	252	Missense	proximal	-2	no	14.098	15.747	EPSD	TCGA	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q5JQC9	AKAP4	P28482	MAPK1	S262	N257K	257	Missense	distal	-5	no	15.486	15.463	EPSD	TCGA;COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q5JQC9	AKAP4	P28482	MAPK1	S262	P255S	255	Missense	distal	-7	no	15.486	15.482	EPSD	TCGA;COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q5JQC9	AKAP4	P28482	MAPK1	S262	P266A	266	Missense	distal	4	no	15.486	15.382	EPSD	TCGA;COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q5JQC9	AKAP4	P28482	MAPK1	S262	R264Q	264	Missense	proximal	2	no	15.486	15.195	EPSD	TCGA;COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q5JQC9	AKAP4	P28482	MAPK1	T265	P266A	266	Missense	proximal	1	no	14.857	7.227	PhosphoSitePlus	TCGA;COSMIC	8.102	Loss
CMGC_MAPK_ERK1_MAPK1_ST	Q5JQC9	AKAP4	P28482	MAPK1	T265	R264Q	264	Missense	proximal	-1	no	14.857	14.836	PhosphoSitePlus	TCGA;COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q5JQC9	AKAP4	P28482	MAPK1	S342	D343H	343	Missense	proximal	1	no	7.273	8.145	EPSD	TCGA;COSMIC	8.102	Gain
CMGC_MAPK_ERK1_MAPK1_ST	Q5JQC9	AKAP4	P28482	MAPK1	S364	K368N	368	Missense	distal	4	no	8.230	8.205	EPSD	TCGA;COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q5JQC9	AKAP4	P28482	MAPK1	S489	L490P	490	Missense	proximal	1	no	7.173	15.983	EPSD	TCGA;COSMIC	8.102	Gain
CMGC_MAPK_ERK1_MAPK1_ST	Q5JQC9	AKAP4	P28482	MAPK1	S492	L490P	490	Missense	proximal	-2	no	7.331	9.249	EPSD	TCGA;COSMIC	8.102	Gain
CMGC_MAPK_ERK1_MAPK1_ST	Q5JQC9	AKAP4	P28482	MAPK1	S603	H604Y	604	Missense	proximal	1	no	7.630	8.444	EPSD	TCGA;COSMIC	8.102	Gain
CMGC_MAPK_ERK1_MAPK1_ST	Q5JQC9	AKAP4	P28482	MAPK1	S784	Q785P	785	Missense	proximal	1	no	3.158	11.652	EPSD	TCGA;COSMIC	8.102	Gain
CMGC_MAPK_ERK1_MAPK1_ST	Q5JQC9	AKAP4	P28482	MAPK1	S808	A809G	809	Missense	proximal	1	no	8.473	6.038	EPSD	TCGA;COSMIC;GDSC	8.102	Loss
CMGC_MAPK_ERK1_MAPK1_ST	Q5JQC9	AKAP4	P28482	MAPK1	S808	V807A	807	Missense	proximal	-1	no	8.473	8.462	EPSD	TCGA;COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q8IZP0	ABI1	P28482	MAPK1	S183	S183G	183	Missense	central	0	yes	18.918	0.000	EPSD;PhosphoSitePlus	TCGA;COSMIC	8.102	Loss
CMGC_MAPK_ERK1_MAPK1_ST	Q8IZP0	ABI1	P28482	MAPK1	S183	P177L	177	Missense	distal	-6	no	18.918	18.826	EPSD;PhosphoSitePlus	TCGA;COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q8IZP0	ABI1	P28482	MAPK1	S183	P181L	181	Missense	proximal	-2	no	18.918	17.001	EPSD;PhosphoSitePlus	TCGA	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q8IZP0	ABI1	P28482	MAPK1	T196	P197H	197	Missense	proximal	1	no	14.788	6.965	EPSD	TCGA;COSMIC	8.102	Loss
CMGC_MAPK_ERK1_MAPK1_ST	Q8IZP0	ABI1	P28482	MAPK1	T238	S240C	240	Missense	proximal	2	no	10.742	10.510	EPSD	TCGA;COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q8IZP0	ABI1	P28482	MAPK1	T336	V339M	339	Missense	distal	3	no	15.442	15.469	EPSD	TCGA;COSMIC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q8IZP0	ABI1	P28482	MAPK1	T336	T340I	340	Missense	distal	4	no	15.442	15.388	EPSD	TCGA;ICGC;COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q8IZP0	ABI1	P28482	MAPK1	T336	R335Q	335	Missense	proximal	-1	no	15.442	15.420	EPSD	TCGA;COSMIC;CCLE	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q8IZP0	ABI1	P28482	MAPK1	S392	Q386R	386	Missense	distal	-6	no	12.998	13.021	EPSD;PhosphoSitePlus	TCGA;COSMIC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q8IZP0	ABI1	P28482	MAPK1	S392	P396L	396	Missense	distal	4	no	12.998	12.878	EPSD;PhosphoSitePlus	TCGA;COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q8IZP0	ABI1	P28482	MAPK1	T394	P396L	396	Missense	proximal	2	no	13.771	13.624	EPSD;PhosphoSitePlus	TCGA;COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q8IZP0	ABI1	P28482	MAPK1	S410	P405L	405	Missense	distal	-5	no	14.946	15.095	PhosphoSitePlus;EPSD	TCGA	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P35658	NUP214	P28482	MAPK1	S30	P35L	35	Missense	distal	5	no	14.354	14.141	EPSD	TCGA;ICGC;COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P35658	NUP214	P28482	MAPK1	S30	D29E	29	Missense	proximal	-1	no	14.354	14.395	EPSD	TCGA;ICGC;COSMIC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P35658	NUP214	P28482	MAPK1	T416	E418Q	418	Missense	proximal	2	no	13.103	12.993	EPSD	TCGA;ICGC;COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P35658	NUP214	P28482	MAPK1	T416	R419Q	419	Missense	distal	3	no	13.103	13.125	EPSD	TCGA;ICGC;GDSC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P35658	NUP214	P28482	MAPK1	S430	S433R	433	Missense	distal	3	no	17.480	17.456	EPSD	TCGA;ICGC;COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P35658	NUP214	P28482	MAPK1	T434	S433R	433	Missense	proximal	-1	no	12.901	12.925	EPSD	TCGA;ICGC;COSMIC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P35658	NUP214	P28482	MAPK1	T437	S433R	433	Missense	distal	-4	no	14.442	14.437	EPSD	TCGA;ICGC;COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P35658	NUP214	P28482	MAPK1	T437	P444T	444	Missense	distal	7	no	14.442	14.605	EPSD	TCGA;ICGC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P35658	NUP214	P28482	MAPK1	S462	A465S	465	Missense	distal	3	no	15.877	15.869	EPSD	TCGA;ICGC;COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P35658	NUP214	P28482	MAPK1	S462	S462L	462	Missense	central	0	yes	15.877	0.000	EPSD	TCGA;ICGC;COSMIC	8.102	Loss
CMGC_MAPK_ERK1_MAPK1_ST	P35658	NUP214	P28482	MAPK1	S483	F484I	484	Missense	proximal	1	no	8.551	5.302	EPSD	TCGA;ICGC;COSMIC	8.102	Loss
CMGC_MAPK_ERK1_MAPK1_ST	P35658	NUP214	P28482	MAPK1	S483	G485R	485	Missense	proximal	2	no	8.551	8.645	EPSD	TCGA;ICGC;COSMIC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P35658	NUP214	P28482	MAPK1	S501	S506F	506	Missense	distal	5	no	10.542	10.345	EPSD	TCGA;ICGC;COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P35658	NUP214	P28482	MAPK1	S501	P500S	500	Missense	proximal	-1	no	10.542	10.499	EPSD	TCGA;ICGC;COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P35658	NUP214	P28482	MAPK1	S501	D507N	507	Missense	distal	6	no	10.542	10.492	EPSD	TCGA;ICGC;COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P35658	NUP214	P28482	MAPK1	T519	S521Y	521	Missense	proximal	2	no	10.270	10.102	EPSD	TCGA;ICGC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P35658	NUP214	P28482	MAPK1	T519	F520L	520	Missense	proximal	1	no	10.270	8.030	EPSD	TCGA;ICGC;COSMIC	8.102	Loss
CMGC_MAPK_ERK1_MAPK1_ST	P35658	NUP214	P28482	MAPK1	T519	S526F	526	Missense	distal	7	no	10.270	10.617	EPSD	TCGA;ICGC;COSMIC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P35658	NUP214	P28482	MAPK1	T519	F522V	522	Missense	distal	3	no	10.270	10.196	EPSD	TCGA;ICGC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P35658	NUP214	P28482	MAPK1	T533	L530V	530	Missense	distal	-3	no	13.509	13.586	EPSD	TCGA;ICGC;COSMIC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P35658	NUP214	P28482	MAPK1	T533	S526F	526	Missense	distal	-7	no	13.509	13.489	EPSD	TCGA;ICGC;COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P35658	NUP214	P28482	MAPK1	T533	S529F	529	Missense	distal	-4	no	13.509	13.248	EPSD	TCGA;ICGC;COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P35658	NUP214	P28482	MAPK1	S537	L530V	530	Missense	distal	-7	no	13.011	13.005	EPSD	TCGA;ICGC;COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P35658	NUP214	P28482	MAPK1	T560	P563S	563	Missense	distal	3	no	12.574	12.643	EPSD	TCGA;ICGC;COSMIC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P35658	NUP214	P28482	MAPK1	T580	S581P	581	Missense	proximal	1	no	5.650	15.045	EPSD	TCGA;ICGC;COSMIC	8.102	Gain
CMGC_MAPK_ERK1_MAPK1_ST	P35658	NUP214	P28482	MAPK1	S581	S579P	579	Missense	proximal	-2	no	5.421	8.255	EPSD	TCGA;ICGC;COSMIC	8.102	Gain
CMGC_MAPK_ERK1_MAPK1_ST	P35658	NUP214	P28482	MAPK1	T598	T592A	592	Missense	distal	-6	no	14.059	14.070	EPSD	TCGA;ICGC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P35658	NUP214	P28482	MAPK1	S610	S616Y	616	Missense	distal	6	no	16.311	15.692	EPSD	TCGA;ICGC;COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P35658	NUP214	P28482	MAPK1	S610	P607H	607	Missense	distal	-3	no	16.311	15.962	EPSD	TCGA;ICGC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P35658	NUP214	P28482	MAPK1	S631	V637M	637	Missense	distal	6	no	8.602	8.383	EPSD	TCGA;ICGC;COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P35658	NUP214	P28482	MAPK1	S646	S642L	642	Missense	distal	-4	no	13.952	13.731	EPSD	TCGA;ICGC;COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P35658	NUP214	P28482	MAPK1	S678	S678C	678	Missense	central	0	yes	16.723	0.000	EPSD	TCGA;COSMIC	8.102	Loss
CMGC_MAPK_ERK1_MAPK1_ST	P35658	NUP214	P28482	MAPK1	S678	P679S	679	Missense	proximal	1	no	16.723	7.328	EPSD	TCGA;COSMIC	8.102	Loss
CMGC_MAPK_ERK1_MAPK1_ST	P35658	NUP214	P28482	MAPK1	T1021	R1020C	1020	Missense	proximal	-1	no	14.288	14.186	EPSD	TCGA;COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P35658	NUP214	P28482	MAPK1	T1021	S1023F	1023	Missense	proximal	2	no	14.288	14.156	EPSD	TCGA;COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P35658	NUP214	P28482	MAPK1	T1021	S1027R	1027	Missense	distal	6	no	14.288	14.181	EPSD	TCGA;COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P35658	NUP214	P28482	MAPK1	S1081	S1087L	1087	Missense	distal	6	no	12.235	11.828	EPSD	TCGA;COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P35658	NUP214	P28482	MAPK1	T1134	P1132L	1132	Missense	proximal	-2	no	15.121	13.204	EPSD	TCGA;COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P35658	NUP214	P28482	MAPK1	T1134	K1129N	1129	Missense	distal	-5	no	15.121	15.144	EPSD	TCGA;COSMIC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P35658	NUP214	P28482	MAPK1	T1134	L1128F	1128	Missense	distal	-6	no	15.121	15.103	EPSD	TCGA;COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P35658	NUP214	P28482	MAPK1	T1134	T1134A	1134	Missense	central	0	yes	15.121	0.000	EPSD	TCGA;COSMIC	8.102	Loss
CMGC_MAPK_ERK1_MAPK1_ST	P35658	NUP214	P28482	MAPK1	T1150	A1148T	1148	Missense	proximal	-2	no	13.990	14.437	EPSD	TCGA	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P35658	NUP214	P28482	MAPK1	T1150	T1150K	1150	Missense	central	0	yes	13.990	0.000	EPSD	TCGA;COSMIC	8.102	Loss
CMGC_MAPK_ERK1_MAPK1_ST	P35658	NUP214	P28482	MAPK1	T1156	T1150K	1150	Missense	distal	-6	no	12.647	12.682	EPSD	TCGA;COSMIC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P35658	NUP214	P28482	MAPK1	T1178	K1173E	1173	Missense	distal	-5	no	9.949	9.972	EPSD	TCGA;COSMIC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P35658	NUP214	P28482	MAPK1	T1178	S1175A	1175	Missense	distal	-3	no	9.949	9.759	EPSD	TCGA	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P35658	NUP214	P28482	MAPK1	T1203	S1207Y	1207	Missense	distal	4	no	13.541	13.346	EPSD	TCGA	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P35658	NUP214	P28482	MAPK1	S1215	S1219L	1219	Missense	distal	4	no	8.721	8.611	EPSD	TCGA;COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P35658	NUP214	P28482	MAPK1	S1215	S1215L	1215	Missense	central	0	yes	8.721	0.000	EPSD	TCGA;COSMIC	8.102	Loss
CMGC_MAPK_ERK1_MAPK1_ST	P35658	NUP214	P28482	MAPK1	S1217	S1219L	1219	Missense	proximal	2	no	13.544	13.424	EPSD	TCGA;COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P35658	NUP214	P28482	MAPK1	S1217	S1215L	1215	Missense	proximal	-2	no	13.544	14.461	EPSD	TCGA;COSMIC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P35658	NUP214	P28482	MAPK1	T1229	I1227L	1227	Missense	proximal	-2	no	14.366	14.344	EPSD	TCGA;COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P35658	NUP214	P28482	MAPK1	T1229	P1232L	1232	Missense	distal	3	no	14.366	14.456	EPSD	TCGA	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P35658	NUP214	P28482	MAPK1	T1231	I1227L	1227	Missense	distal	-4	no	11.892	12.259	EPSD	TCGA;COSMIC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P35658	NUP214	P28482	MAPK1	T1231	P1232L	1232	Missense	proximal	1	no	11.892	3.083	EPSD	TCGA	8.102	Loss
CMGC_MAPK_ERK1_MAPK1_ST	P35658	NUP214	P28482	MAPK1	S1272	P1274L	1274	Missense	proximal	2	no	13.561	13.413	EPSD	TCGA;COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P35658	NUP214	P28482	MAPK1	S1272	E1266G	1266	Missense	distal	-6	no	13.561	13.507	EPSD	TCGA;COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P35658	NUP214	P28482	MAPK1	T1284	G1286E	1286	Missense	proximal	2	no	13.606	13.520	EPSD	TCGA;COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P35658	NUP214	P28482	MAPK1	T1312	S1307F	1307	Missense	distal	-5	no	13.657	13.745	EPSD	TCGA;ICGC;COSMIC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P35658	NUP214	P28482	MAPK1	T1312	E1319K	1319	Missense	distal	7	no	13.657	13.665	EPSD	TCGA;COSMIC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P35658	NUP214	P28482	MAPK1	T1312	L1310M	1310	Missense	proximal	-2	no	13.657	11.560	EPSD	TCGA;ICGC;COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P35658	NUP214	P28482	MAPK1	S2002	G2009S	2009	Missense	distal	7	no	13.857	13.788	EPSD	TCGA;COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P35658	NUP214	P28482	MAPK1	S2002	P2003H	2003	Missense	proximal	1	no	13.857	6.033	EPSD	TCGA	8.102	Loss
CMGC_MAPK_ERK1_MAPK1_ST	Q15672	TWIST1	P28482	MAPK1	S99	G97S	97	Missense	proximal	-2	no	12.934	13.294	EPSD	TCGA;ICGC;COSMIC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q15672	TWIST1	P28482	MAPK1	S102	G97S	97	Missense	distal	-5	no	9.723	9.730	EPSD	TCGA;ICGC;COSMIC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q15796	SMAD2	P28482	MAPK1	S21	L16V	16	Missense	distal	-5	no	8.307	8.254	EPSD	TCGA;ICGC;COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q15796	SMAD2	P28482	MAPK1	T172	P176R	176	Missense	distal	4	no	12.938	12.904	EPSD	TCGA	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q15796	SMAD2	P28482	MAPK1	S245	S250F	250	Missense	distal	5	no	15.166	14.968	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q15796	SMAD2	P28482	MAPK1	S250	S250F	250	Missense	central	0	yes	16.438	0.000	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	8.102	Loss
CMGC_MAPK_ERK1_MAPK1_ST	Q15796	SMAD2	P28482	MAPK1	S255	D262Y	262	Missense	distal	7	no	16.866	17.388	PhosphoSitePlus;EPSD	TCGA;ICGC;COSMIC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q15796	SMAD2	P28482	MAPK1	S255	S250F	250	Missense	distal	-5	no	16.866	16.954	PhosphoSitePlus;EPSD	TCGA;ICGC;COSMIC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q15796	SMAD2	P28482	MAPK1	T454	K451E	451	Missense	distal	-3	no	9.006	9.084	EPSD	TCGA;ICGC;COSMIC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q15796	SMAD2	P28482	MAPK1	T454	D450E	450	Missense	distal	-4	no	9.006	8.992	EPSD	TCGA;ICGC;COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q15796	SMAD2	P28482	MAPK1	T454	D450N	450	Missense	distal	-4	no	9.006	8.978	EPSD	TCGA;ICGC;COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q15796	SMAD2	P28482	MAPK1	T454	G457A	457	Missense	distal	3	no	9.006	9.001	EPSD	TCGA;ICGC;COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q15796	SMAD2	P28482	MAPK1	S458	K451E	451	Missense	distal	-7	no	12.677	12.684	EPSD	TCGA;ICGC;COSMIC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q15796	SMAD2	P28482	MAPK1	S458	G457A	457	Missense	proximal	-1	no	12.677	12.695	EPSD	TCGA;ICGC;COSMIC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P01100	FOS	P28482	MAPK1	S133	E138D	138	Missense	distal	5	no	13.006	13.075	EPSD	TCGA;ICGC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P01100	FOS	P28482	MAPK1	T325	P326S	326	Missense	proximal	1	no	13.838	4.443	EPSD	TCGA;COSMIC	8.102	Loss
CMGC_MAPK_ERK1_MAPK1_ST	P01100	FOS	P28482	MAPK1	T325	P332L	332	Missense	distal	7	no	13.838	14.138	EPSD	TCGA;ICGC;COSMIC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P01100	FOS	P28482	MAPK1	T331	P326S	326	Missense	distal	-5	no	15.184	15.258	EPSD	TCGA;COSMIC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P01100	FOS	P28482	MAPK1	T331	S333C	333	Missense	proximal	2	no	15.184	14.952	EPSD	TCGA;ICGC;COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P01100	FOS	P28482	MAPK1	T331	P332L	332	Missense	proximal	1	no	15.184	6.375	EPSD	TCGA;ICGC;COSMIC	8.102	Loss
CMGC_MAPK_ERK1_MAPK1_ST	P01100	FOS	P28482	MAPK1	T331	A336D	336	Missense	distal	5	no	15.184	15.369	EPSD	TCGA;ICGC;COSMIC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P01100	FOS	P28482	MAPK1	S362	S369P	369	Missense	distal	7	no	10.992	10.981	EPSD	TCGA	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P01100	FOS	P28482	MAPK1	S362	N365I	365	Missense	distal	3	no	10.992	11.129	EPSD	TCGA;ICGC;COSMIC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P01100	FOS	P28482	MAPK1	S362	S363N	363	Missense	proximal	1	no	10.992	0.664	EPSD	TCGA;COSMIC	8.102	Loss
CMGC_MAPK_ERK1_MAPK1_ST	P01100	FOS	P28482	MAPK1	S368	S369P	369	Missense	proximal	1	no	5.120	14.515	EPSD	TCGA	8.102	Gain
CMGC_MAPK_ERK1_MAPK1_ST	P01100	FOS	P28482	MAPK1	S369	S369P	369	Missense	central	0	yes	11.330	0.000	EPSD	TCGA	8.102	Loss
CMGC_MAPK_ERK1_MAPK1_ST	P01100	FOS	P28482	MAPK1	S369	N365I	365	Missense	distal	-4	no	11.330	10.701	EPSD	TCGA;ICGC;COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P01100	FOS	P28482	MAPK1	S369	S363N	363	Missense	distal	-6	no	11.330	11.333	EPSD	TCGA;COSMIC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P01100	FOS	P28482	MAPK1	S371	S369P	369	Missense	proximal	-2	no	8.188	11.022	EPSD	TCGA	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P01100	FOS	P28482	MAPK1	S371	N365I	365	Missense	distal	-6	no	8.188	8.083	EPSD	TCGA;ICGC;COSMIC	8.102	Loss
CMGC_MAPK_ERK1_MAPK1_ST	P01100	FOS	P28482	MAPK1	S373	S369P	369	Missense	distal	-4	no	9.180	9.263	EPSD	TCGA	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P01100	FOS	P28482	MAPK1	S374	S369P	369	Missense	distal	-5	no	17.547	17.473	EPSD	TCGA	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P01100	FOS	P28482	MAPK1	T376	S369P	369	Missense	distal	-7	no	8.102	8.106	EPSD	TCGA	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q14674	ESPL1	P28482	MAPK1	S330	R334W	334	Missense	distal	4	no	13.223	12.940	EPSD	TCGA;ICGC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q14674	ESPL1	P28482	MAPK1	S1153	S1153N	1153	Missense	central	0	yes	13.426	0.000	EPSD	TCGA;ICGC;COSMIC	8.102	Loss
CMGC_MAPK_ERK1_MAPK1_ST	Q14674	ESPL1	P28482	MAPK1	S1153	D1147N	1147	Missense	distal	-6	no	13.426	13.381	EPSD	TCGA;ICGC;COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q14674	ESPL1	P28482	MAPK1	T1210	S1205F	1205	Missense	distal	-5	no	14.034	14.122	EPSD	TCGA;ICGC;COSMIC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q14674	ESPL1	P28482	MAPK1	T1346	P1349H	1349	Missense	distal	3	no	16.955	17.044	EPSD	TCGA;ICGC;COSMIC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q14674	ESPL1	P28482	MAPK1	S1406	D1403N	1403	Missense	distal	-3	no	8.549	8.516	EPSD	TCGA;ICGC;COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q14674	ESPL1	P28482	MAPK1	T1519	E1525V	1525	Missense	distal	6	no	13.316	13.067	EPSD	TCGA;ICGC;COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q14674	ESPL1	P28482	MAPK1	S1545	E1551D	1551	Missense	distal	6	no	12.245	12.166	EPSD	TCGA;ICGC;COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q14674	ESPL1	P28482	MAPK1	S1678	G1685V	1685	Missense	distal	7	no	9.465	9.679	EPSD	TCGA;ICGC;COSMIC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q14674	ESPL1	P28482	MAPK1	S1678	R1672H	1672	Missense	distal	-6	no	9.465	9.382	EPSD	TCGA;ICGC;COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q14674	ESPL1	P28482	MAPK1	S1678	S1678F	1678	Missense	central	0	yes	9.465	0.000	EPSD	TCGA;ICGC;COSMIC	8.102	Loss
CMGC_MAPK_ERK1_MAPK1_ST	Q14674	ESPL1	P28482	MAPK1	S1678	R1672C	1672	Missense	distal	-6	no	9.465	9.290	EPSD	TCGA;ICGC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q14674	ESPL1	P28482	MAPK1	S2118	Y2113H	2113	Missense	distal	-5	no	8.539	8.458	EPSD	TCGA;ICGC;COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P19878	NCF2	P28482	MAPK1	T233	P231L	231	Missense	proximal	-2	no	16.494	14.577	PhosphoSitePlus	TCGA;ICGC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P19878	NCF2	P28482	MAPK1	T233	E235D	235	Missense	proximal	2	no	16.494	16.546	PhosphoSitePlus	TCGA;ICGC;COSMIC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P19878	NCF2	P28482	MAPK1	S312	D316N	316	Missense	distal	4	no	14.245	14.304	EPSD	TCGA;ICGC;COSMIC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P19878	NCF2	P28482	MAPK1	S312	Q308H	308	Missense	distal	-4	no	14.245	14.196	EPSD	TCGA;ICGC;COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P19878	NCF2	P28482	MAPK1	S312	P313Q	313	Missense	proximal	1	no	14.245	5.751	EPSD	TCGA;ICGC;COSMIC	8.102	Loss
CMGC_MAPK_ERK1_MAPK1_ST	P19878	NCF2	P28482	MAPK1	S312	P313L	313	Missense	proximal	1	no	14.245	5.435	EPSD	TCGA;ICGC;COSMIC	8.102	Loss
CMGC_MAPK_ERK1_MAPK1_ST	P19878	NCF2	P28482	MAPK1	S312	S312Y	312	Missense	central	0	yes	14.245	0.000	EPSD	TCGA;ICGC;COSMIC	8.102	Loss
CMGC_MAPK_ERK1_MAPK1_ST	P19878	NCF2	P28482	MAPK1	S312	A319S	319	Missense	distal	7	no	14.245	14.064	EPSD	TCGA;ICGC;COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P19878	NCF2	P28482	MAPK1	S312	E309D	309	Missense	distal	-3	no	14.245	14.296	EPSD	TCGA;ICGC;COSMIC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P19878	NCF2	P28482	MAPK1	S332	A325D	325	Missense	distal	-7	no	14.060	14.059	EPSD	TCGA;ICGC;COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P19878	NCF2	P28482	MAPK1	S332	G334S	334	Missense	proximal	2	no	14.060	14.014	EPSD	TCGA;ICGC;COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P28562	DUSP1	P28482	MAPK1	T141	S137R	137	Missense	distal	-4	no	10.564	10.558	EPSD	TCGA;ICGC;COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P28562	DUSP1	P28482	MAPK1	S323	P324L	324	Missense	proximal	1	no	14.078	5.268	PhosphoSitePlus;EPSD	TCGA;ICGC;COSMIC	8.102	Loss
CMGC_MAPK_ERK1_MAPK1_ST	P28562	DUSP1	P28482	MAPK1	S323	A325T	325	Missense	proximal	2	no	14.078	14.157	PhosphoSitePlus;EPSD	TCGA;ICGC;COSMIC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P28562	DUSP1	P28482	MAPK1	S323	S318L	318	Missense	distal	-5	no	14.078	14.153	PhosphoSitePlus;EPSD	TCGA;ICGC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P28562	DUSP1	P28482	MAPK1	S359	A353V	353	Missense	distal	-6	no	16.428	16.381	EPSD	TCGA;ICGC;COSMIC;GDSC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P28562	DUSP1	P28482	MAPK1	S359	L354P	354	Missense	distal	-5	no	16.428	16.279	EPSD	TCGA;ICGC;COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q15648	MED1	P28482	MAPK1	T212	H218Y	218	Missense	distal	6	no	13.734	13.421	EPSD	TCGA;ICGC;COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q15648	MED1	P28482	MAPK1	T212	G209V	209	Missense	distal	-3	no	13.734	13.615	EPSD	TCGA;ICGC;COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q15648	MED1	P28482	MAPK1	S238	E244K	244	Missense	distal	6	no	15.156	15.179	EPSD	TCGA;ICGC;COSMIC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q15648	MED1	P28482	MAPK1	S238	K235R	235	Missense	distal	-3	no	15.156	15.394	EPSD	TCGA;ICGC;COSMIC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q15648	MED1	P28482	MAPK1	S434	E441K	441	Missense	distal	7	no	12.254	12.262	EPSD	TCGA;ICGC;COSMIC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q15648	MED1	P28482	MAPK1	S434	S434F	434	Missense	central	0	yes	12.254	0.000	EPSD	TCGA;ICGC;COSMIC	8.102	Loss
CMGC_MAPK_ERK1_MAPK1_ST	Q15648	MED1	P28482	MAPK1	S434	R427I	427	Missense	distal	-7	no	12.254	12.228	EPSD	TCGA;ICGC;COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q15648	MED1	P28482	MAPK1	S434	P435L	435	Missense	proximal	1	no	12.254	3.445	EPSD	TCGA;ICGC;COSMIC	8.102	Loss
CMGC_MAPK_ERK1_MAPK1_ST	Q15648	MED1	P28482	MAPK1	S434	G436W	436	Missense	proximal	2	no	12.254	11.981	EPSD	TCGA;ICGC;COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q15648	MED1	P28482	MAPK1	T522	P523Q	523	Missense	proximal	1	no	12.164	3.671	EPSD	TCGA;ICGC;COSMIC	8.102	Loss
CMGC_MAPK_ERK1_MAPK1_ST	Q15648	MED1	P28482	MAPK1	T562	P563S	563	Missense	proximal	1	no	13.604	4.209	EPSD	TCGA;ICGC;COSMIC	8.102	Loss
CMGC_MAPK_ERK1_MAPK1_ST	Q15648	MED1	P28482	MAPK1	T562	N565I	565	Missense	distal	3	no	13.604	13.741	EPSD	TCGA;ICGC;COSMIC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q15648	MED1	P28482	MAPK1	T562	N555S	555	Missense	distal	-7	no	13.604	13.602	EPSD	TCGA;ICGC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q15648	MED1	P28482	MAPK1	T562	T561N	561	Missense	proximal	-1	no	13.604	13.652	EPSD	TCGA;ICGC;COSMIC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q15648	MED1	P28482	MAPK1	T562	M557T	557	Missense	distal	-5	no	13.604	13.555	EPSD	TCGA;ICGC;COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q15648	MED1	P28482	MAPK1	S621	T628M	628	Missense	distal	7	no	12.139	12.346	EPSD	TCGA;ICGC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q15648	MED1	P28482	MAPK1	S621	P625A	625	Missense	distal	4	no	12.139	12.035	EPSD	TCGA;ICGC;COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q15648	MED1	P28482	MAPK1	S621	H627D	627	Missense	distal	6	no	12.139	12.399	EPSD	TCGA;ICGC;COSMIC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q15648	MED1	P28482	MAPK1	T623	T628M	628	Missense	distal	5	no	14.078	13.947	EPSD	TCGA;ICGC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q15648	MED1	P28482	MAPK1	T623	P625A	625	Missense	proximal	2	no	14.078	13.948	EPSD	TCGA;ICGC;COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q15648	MED1	P28482	MAPK1	T623	H627D	627	Missense	distal	4	no	14.078	14.146	EPSD	TCGA;ICGC;COSMIC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q15648	MED1	P28482	MAPK1	T628	T628M	628	Missense	central	0	yes	13.597	0.000	EPSD	TCGA;ICGC	8.102	Loss
CMGC_MAPK_ERK1_MAPK1_ST	Q15648	MED1	P28482	MAPK1	T628	P625A	625	Missense	distal	-3	no	13.597	13.230	EPSD	TCGA;ICGC;COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q15648	MED1	P28482	MAPK1	T628	S634L	634	Missense	distal	6	no	13.597	13.191	EPSD	TCGA;ICGC;COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q15648	MED1	P28482	MAPK1	T628	H627D	627	Missense	proximal	-1	no	13.597	13.584	EPSD	TCGA;ICGC;COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q15648	MED1	P28482	MAPK1	S633	S634L	634	Missense	proximal	1	no	7.726	8.311	EPSD	TCGA;ICGC;COSMIC	8.102	Gain
CMGC_MAPK_ERK1_MAPK1_ST	Q15648	MED1	P28482	MAPK1	S664	S671Y	671	Missense	distal	7	no	12.861	13.379	EPSD	TCGA;ICGC;COSMIC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q15648	MED1	P28482	MAPK1	S664	S671F	671	Missense	distal	7	no	12.861	13.209	EPSD	TCGA;ICGC;COSMIC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q15648	MED1	P28482	MAPK1	S675	S682L	682	Missense	distal	7	no	13.798	14.086	EPSD	TCGA;ICGC;COSMIC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q15648	MED1	P28482	MAPK1	S675	S671Y	671	Missense	distal	-4	no	13.798	13.209	EPSD	TCGA;ICGC;COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q15648	MED1	P28482	MAPK1	S675	R677H	677	Missense	proximal	2	no	13.798	13.555	EPSD	TCGA;ICGC;COSMIC;GDSC;CCLE	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q15648	MED1	P28482	MAPK1	S675	R677C	677	Missense	proximal	2	no	13.798	13.425	EPSD	TCGA	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q15648	MED1	P28482	MAPK1	S675	S682T	682	Missense	distal	7	no	13.798	13.950	EPSD	TCGA;ICGC;COSMIC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q15648	MED1	P28482	MAPK1	S675	S671F	671	Missense	distal	-4	no	13.798	13.537	EPSD	TCGA;ICGC;COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q15648	MED1	P28482	MAPK1	T805	S810Y	810	Missense	distal	5	no	14.897	14.608	EPSD	TCGA;ICGC;COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q15648	MED1	P28482	MAPK1	S848	G847R	847	Missense	proximal	-1	no	13.014	13.049	EPSD	TCGA;ICGC;COSMIC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q15648	MED1	P28482	MAPK1	S853	G847R	847	Missense	distal	-6	no	12.481	12.532	EPSD	TCGA;ICGC;COSMIC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q15648	MED1	P28482	MAPK1	S1021	H1024Y	1024	Missense	distal	3	no	12.058	12.097	EPSD	TCGA;ICGC;COSMIC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q15648	MED1	P28482	MAPK1	S1042	S1049C	1049	Missense	distal	7	no	13.323	13.982	EPSD	TCGA;ICGC;COSMIC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q15648	MED1	P28482	MAPK1	S1045	S1049C	1049	Missense	distal	4	no	10.040	9.758	EPSD	TCGA;ICGC;COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q15648	MED1	P28482	MAPK1	T1051	S1049C	1049	Missense	proximal	-2	no	10.652	9.720	EPSD	TCGA;ICGC;COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q15648	MED1	P28482	MAPK1	S1155	S1156F	1156	Missense	proximal	1	no	6.000	8.825	EPSD	TCGA;ICGC;COSMIC	8.102	Gain
CMGC_MAPK_ERK1_MAPK1_ST	Q15648	MED1	P28482	MAPK1	S1156	G1154D	1154	Missense	proximal	-2	no	14.765	14.657	EPSD	TCGA;ICGC;COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q15648	MED1	P28482	MAPK1	S1156	S1149F	1149	Missense	distal	-7	no	14.765	14.745	EPSD	TCGA;ICGC;COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q15648	MED1	P28482	MAPK1	S1156	S1156F	1156	Missense	central	0	yes	14.765	0.000	EPSD	TCGA;ICGC;COSMIC	8.102	Loss
CMGC_MAPK_ERK1_MAPK1_ST	Q15648	MED1	P28482	MAPK1	S1192	H1195Y	1195	Missense	distal	3	no	14.426	14.465	EPSD	TCGA;ICGC;COSMIC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q15648	MED1	P28482	MAPK1	S1207	P1208A	1208	Missense	proximal	1	no	13.792	6.161	EPSD	TCGA;ICGC;COSMIC	8.102	Loss
CMGC_MAPK_ERK1_MAPK1_ST	Q15648	MED1	P28482	MAPK1	T1215	P1208A	1208	Missense	distal	-7	no	15.062	15.059	EPSD	TCGA;ICGC;COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q15648	MED1	P28482	MAPK1	T1215	S1218C	1218	Missense	distal	3	no	15.062	15.165	EPSD	TCGA;ICGC;COSMIC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q15648	MED1	P28482	MAPK1	S1223	S1227L	1227	Missense	distal	4	no	13.462	13.353	EPSD	TCGA;ICGC;COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q15648	MED1	P28482	MAPK1	S1223	S1218C	1218	Missense	distal	-5	no	13.462	13.666	EPSD	TCGA;ICGC;COSMIC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q15648	MED1	P28482	MAPK1	S1294	P1301L	1301	Missense	distal	7	no	14.110	14.409	EPSD	TCGA;ICGC;COSMIC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q15648	MED1	P28482	MAPK1	S1401	P1402R	1402	Missense	proximal	1	no	14.046	4.392	EPSD	TCGA;ICGC;COSMIC	8.102	Loss
CMGC_MAPK_ERK1_MAPK1_ST	Q15648	MED1	P28482	MAPK1	S1401	V1408M	1408	Missense	distal	7	no	14.046	14.123	EPSD	TCGA;ICGC;COSMIC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q15648	MED1	P28482	MAPK1	S1401	K1407T	1407	Missense	distal	6	no	14.046	13.779	EPSD	TCGA;ICGC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q15648	MED1	P28482	MAPK1	S1433	S1439F	1439	Missense	distal	6	no	15.078	14.637	EPSD	TCGA;ICGC;COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q15648	MED1	P28482	MAPK1	S1433	P1434L	1434	Missense	proximal	1	no	15.078	6.268	EPSD	TCGA;ICGC;COSMIC	8.102	Loss
CMGC_MAPK_ERK1_MAPK1_ST	Q15648	MED1	P28482	MAPK1	S1433	I1436M	1436	Missense	distal	3	no	15.078	15.035	EPSD	TCGA;ICGC;COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q15648	MED1	P28482	MAPK1	T1440	S1439F	1439	Missense	proximal	-1	no	12.233	12.187	EPSD	TCGA;ICGC;COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q15648	MED1	P28482	MAPK1	T1440	P1434L	1434	Missense	distal	-6	no	12.233	12.141	EPSD	TCGA;ICGC;COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q15648	MED1	P28482	MAPK1	T1440	I1436M	1436	Missense	distal	-4	no	12.233	12.438	EPSD	TCGA;ICGC;COSMIC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q15648	MED1	P28482	MAPK1	S1447	P1448S	1448	Missense	proximal	1	no	13.513	4.118	EPSD	TCGA;ICGC;COSMIC	8.102	Loss
CMGC_MAPK_ERK1_MAPK1_ST	Q15648	MED1	P28482	MAPK1	S1447	P1448A	1448	Missense	proximal	1	no	13.513	5.882	EPSD	TCGA;ICGC;COSMIC	8.102	Loss
CMGC_MAPK_ERK1_MAPK1_ST	Q15648	MED1	P28482	MAPK1	S1453	P1448S	1448	Missense	distal	-5	no	14.493	14.567	EPSD	TCGA;ICGC;COSMIC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q15648	MED1	P28482	MAPK1	S1453	P1448A	1448	Missense	distal	-5	no	14.493	14.618	EPSD	TCGA;ICGC;COSMIC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q15648	MED1	P28482	MAPK1	S1479	Q1477H	1477	Missense	proximal	-2	no	13.366	13.604	EPSD	TCGA;ICGC;COSMIC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q15648	MED1	P28482	MAPK1	S1479	S1475F	1475	Missense	distal	-4	no	13.366	13.105	EPSD	TCGA	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q15648	MED1	P28482	MAPK1	S1479	D1484V	1484	Missense	distal	5	no	13.366	13.198	EPSD	TCGA;ICGC;COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q15648	MED1	P28482	MAPK1	S1479	D1484N	1484	Missense	distal	5	no	13.366	13.268	EPSD	TCGA;ICGC;COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q15648	MED1	P28482	MAPK1	S1532	H1526D	1526	Missense	distal	-6	no	9.948	10.046	EPSD	TCGA;ICGC;COSMIC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q15648	MED1	P28482	MAPK1	S1532	S1527G	1527	Missense	distal	-5	no	9.948	9.942	EPSD	TCGA;ICGC;COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q15648	MED1	P28482	MAPK1	S1558	S1558L	1558	Missense	central	0	yes	8.659	0.000	EPSD	TCGA;ICGC;COSMIC	8.102	Loss
CMGC_MAPK_ERK1_MAPK1_ST	Q15648	MED1	P28482	MAPK1	S1558	A1554S	1554	Missense	distal	-4	no	8.659	8.868	EPSD	TCGA;ICGC;COSMIC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q15648	MED1	P28482	MAPK1	S1558	S1561I	1561	Missense	distal	3	no	8.659	8.717	EPSD	TCGA;ICGC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q15648	MED1	P28482	MAPK1	S1561	S1558L	1558	Missense	distal	-3	no	15.612	15.405	EPSD	TCGA;ICGC;COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q15648	MED1	P28482	MAPK1	S1561	A1554S	1554	Missense	distal	-7	no	15.612	15.610	EPSD	TCGA;ICGC;COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q15648	MED1	P28482	MAPK1	S1561	S1561I	1561	Missense	central	0	yes	15.612	0.000	EPSD	TCGA;ICGC	8.102	Loss
CMGC_MAPK_ERK1_MAPK1_ST	P19525	EIF2AK2	P28482	MAPK1	T16	E12Q	12	Missense	distal	-4	no	12.588	12.424	EPSD	TCGA;ICGC;COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P19525	EIF2AK2	P28482	MAPK1	T16	F10L	10	Missense	distal	-6	no	12.588	12.606	EPSD	TCGA;ICGC;COSMIC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P19525	EIF2AK2	P28482	MAPK1	S83	T88A	88	Missense	distal	5	no	14.665	14.579	EPSD	TCGA;ICGC;COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P19525	EIF2AK2	P28482	MAPK1	S83	K79N	79	Missense	distal	-4	no	14.665	14.633	EPSD	TCGA;ICGC;COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P19525	EIF2AK2	P28482	MAPK1	S83	K77T	77	Missense	distal	-6	no	14.665	14.630	EPSD	TCGA;ICGC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P19525	EIF2AK2	P28482	MAPK1	T529	I532M	532	Missense	distal	3	no	8.525	8.482	EPSD	TCGA;ICGC;COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P19525	EIF2AK2	P28482	MAPK1	T529	L536F	536	Missense	distal	7	no	8.525	8.584	EPSD	TCGA;ICGC;COSMIC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P19525	EIF2AK2	P28482	MAPK1	T535	I532M	532	Missense	distal	-3	no	8.639	8.642	EPSD	TCGA;ICGC;COSMIC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P19525	EIF2AK2	P28482	MAPK1	T535	L536F	536	Missense	proximal	1	no	8.639	10.879	EPSD	TCGA;ICGC;COSMIC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P19525	EIF2AK2	P28482	MAPK1	T535	E531K	531	Missense	distal	-4	no	8.639	8.657	EPSD	TCGA;ICGC;COSMIC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P19525	EIF2AK2	P28482	MAPK1	S542	L536F	536	Missense	distal	-6	no	14.844	14.825	EPSD	TCGA;ICGC;COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P19525	EIF2AK2	P28482	MAPK1	S542	E544D	544	Missense	proximal	2	no	14.844	14.895	EPSD	TCGA;ICGC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q92974	ARHGEF2	P28482	MAPK1	S163	R168C	168	Missense	distal	5	no	15.493	15.061	EPSD	TCGA;ICGC;COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q92974	ARHGEF2	P28482	MAPK1	T455	R452W	452	Missense	distal	-3	no	11.810	11.112	EPSD	TCGA;COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q92974	ARHGEF2	P28482	MAPK1	T455	P456S	456	Missense	proximal	1	no	11.810	2.415	EPSD	TCGA;COSMIC	8.102	Loss
CMGC_MAPK_ERK1_MAPK1_ST	Q92974	ARHGEF2	P28482	MAPK1	T455	P451T	451	Missense	distal	-4	no	11.810	11.497	EPSD	TCGA;COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q92974	ARHGEF2	P28482	MAPK1	S648	R650C	650	Missense	proximal	2	no	16.786	16.413	EPSD	TCGA;COSMIC;CCLE	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q92974	ARHGEF2	P28482	MAPK1	S648	R653Q	653	Missense	distal	5	no	16.786	16.616	EPSD	TCGA;COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q92974	ARHGEF2	P28482	MAPK1	T679	V674M	674	Missense	distal	-5	no	13.335	13.391	PhosphoSitePlus	TCGA	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q92974	ARHGEF2	P28482	MAPK1	S696	P697L	697	Missense	proximal	1	no	15.514	6.704	EPSD	TCGA;COSMIC	8.102	Loss
CMGC_MAPK_ERK1_MAPK1_ST	Q92974	ARHGEF2	P28482	MAPK1	S696	P697A	697	Missense	proximal	1	no	15.514	7.883	EPSD	TCGA;COSMIC	8.102	Loss
CMGC_MAPK_ERK1_MAPK1_ST	Q92974	ARHGEF2	P28482	MAPK1	S696	T695M	695	Missense	proximal	-1	no	15.514	15.506	EPSD	TCGA;COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q92974	ARHGEF2	P28482	MAPK1	S733	P734L	734	Missense	proximal	1	no	15.414	6.605	EPSD	TCGA	8.102	Loss
CMGC_MAPK_ERK1_MAPK1_ST	Q92974	ARHGEF2	P28482	MAPK1	S733	A738V	738	Missense	distal	5	no	15.414	15.431	EPSD	TCGA;COSMIC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q92974	ARHGEF2	P28482	MAPK1	S932	R936W	936	Missense	distal	4	no	13.424	13.141	EPSD	TCGA;COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q92974	ARHGEF2	P28482	MAPK1	S932	P933L	933	Missense	proximal	1	no	13.424	4.614	EPSD	TCGA;COSMIC	8.102	Loss
CMGC_MAPK_ERK1_MAPK1_ST	Q92974	ARHGEF2	P28482	MAPK1	S956	S953R	953	Missense	distal	-3	no	13.951	14.108	EPSD	TCGA;COSMIC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q92974	ARHGEF2	P28482	MAPK1	S956	R954H	954	Missense	proximal	-2	no	13.951	13.015	EPSD	TCGA;COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q92974	ARHGEF2	P28482	MAPK1	S956	R954C	954	Missense	proximal	-2	no	13.951	12.003	EPSD	TCGA;COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q92974	ARHGEF2	P28482	MAPK1	S956	S960N	960	Missense	distal	4	no	13.951	13.914	EPSD	TCGA;COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q92974	ARHGEF2	P28482	MAPK1	S960	R966T	966	Missense	distal	6	no	17.909	17.806	EPSD	TCGA;COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q92974	ARHGEF2	P28482	MAPK1	S960	S953R	953	Missense	distal	-7	no	17.909	17.908	EPSD	TCGA;COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q92974	ARHGEF2	P28482	MAPK1	S960	R954H	954	Missense	distal	-6	no	17.909	17.826	EPSD	TCGA;COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q92974	ARHGEF2	P28482	MAPK1	S960	R954C	954	Missense	distal	-6	no	17.909	17.734	EPSD	TCGA;COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q92974	ARHGEF2	P28482	MAPK1	S960	S960N	960	Missense	central	0	yes	17.909	0.000	EPSD	TCGA;COSMIC	8.102	Loss
CMGC_MAPK_ERK1_MAPK1_ST	O94811	TPPP	P28482	MAPK1	T14	R13M	13	Missense	proximal	-1	no	15.180	15.150	EPSD	TCGA;ICGC;COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	O94811	TPPP	P28482	MAPK1	S18	R13M	13	Missense	distal	-5	no	19.644	19.749	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	O94811	TPPP	P28482	MAPK1	S45	A50V	50	Missense	distal	5	no	13.039	13.057	EPSD	TCGA;ICGC;COSMIC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	O94811	TPPP	P28482	MAPK1	S45	L48F	48	Missense	distal	3	no	13.039	13.081	EPSD	TCGA;ICGC;COSMIC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	O94811	TPPP	P28482	MAPK1	S160	S159L	159	Missense	proximal	-1	no	12.599	12.583	PhosphoSitePlus;EPSD	TCGA;ICGC;COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	O75582	RPS6KA5	P28482	MAPK1	S15	G21E	21	Missense	distal	6	no	8.098	8.209	EPSD	TCGA;ICGC;COSMIC	8.102	Gain
CMGC_MAPK_ERK1_MAPK1_ST	O75582	RPS6KA5	P28482	MAPK1	S212	A210V	210	Missense	proximal	-2	no	7.376	8.651	EPSD	TCGA;ICGC;COSMIC	8.102	Gain
CMGC_MAPK_ERK1_MAPK1_ST	O75582	RPS6KA5	P28482	MAPK1	S253	S253Y	253	Missense	central	0	yes	12.735	0.000	EPSD	TCGA;ICGC;COSMIC	8.102	Loss
CMGC_MAPK_ERK1_MAPK1_ST	O75582	RPS6KA5	P28482	MAPK1	S253	D258N	258	Missense	distal	5	no	12.735	12.638	EPSD	TCGA;ICGC;COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	O75582	RPS6KA5	P28482	MAPK1	S360	T353A	353	Missense	distal	-7	no	14.625	14.640	PhosphoSitePlus;EPSD	TCGA;COSMIC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	O75582	RPS6KA5	P28482	MAPK1	T581	K580N	580	Missense	proximal	-1	no	16.095	16.088	EPSD;PhosphoSitePlus	TCGA;COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	O75582	RPS6KA5	P28482	MAPK1	T581	H587Q	587	Missense	distal	6	no	16.095	16.113	EPSD;PhosphoSitePlus	TCGA;ICGC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	O75582	RPS6KA5	P28482	MAPK1	T700	P701L	701	Missense	proximal	1	no	14.834	6.025	EPSD	TCGA;COSMIC	8.102	Loss
CMGC_MAPK_ERK1_MAPK1_ST	O75582	RPS6KA5	P28482	MAPK1	T700	I703S	703	Missense	distal	3	no	14.834	14.776	EPSD	TCGA;ICGC;COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	O75582	RPS6KA5	P28482	MAPK1	T775	H769Y	769	Missense	distal	-6	no	15.058	14.992	EPSD	TCGA;COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	O75582	RPS6KA5	P28482	MAPK1	T775	P782H	782	Missense	distal	7	no	15.058	15.292	EPSD	TCGA	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	O75582	RPS6KA5	P28482	MAPK1	T775	S768F	768	Missense	distal	-7	no	15.058	15.038	EPSD	TCGA	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	O75582	RPS6KA5	P28482	MAPK1	T793	F797L	797	Missense	distal	4	no	9.441	9.509	EPSD	TCGA;COSMIC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	O75582	RPS6KA5	P28482	MAPK1	T793	N789D	789	Missense	distal	-4	no	9.441	9.469	EPSD	TCGA;COSMIC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	O75582	RPS6KA5	P28482	MAPK1	T793	D787V	787	Missense	distal	-6	no	9.441	9.331	EPSD	TCGA;COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P29590	PML	P28482	MAPK1	S40	A47T	47	Missense	distal	7	no	13.758	13.729	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P29590	PML	P28482	MAPK1	T196	R195C	195	Missense	proximal	-1	no	14.026	13.924	EPSD	TCGA;ICGC;COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P29590	PML	P28482	MAPK1	T196	S190C	190	Missense	distal	-6	no	14.026	13.885	EPSD	TCGA;ICGC;COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P29590	PML	P28482	MAPK1	T196	R195H	195	Missense	proximal	-1	no	14.026	14.003	EPSD	TCGA;ICGC;COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P29590	PML	P28482	MAPK1	S403	P410S	410	Missense	distal	7	no	12.980	12.991	EPSD	TCGA;ICGC;COSMIC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P29590	PML	P28482	MAPK1	T409	P410S	410	Missense	proximal	1	no	13.534	4.139	EPSD	TCGA;ICGC;COSMIC	8.102	Loss
CMGC_MAPK_ERK1_MAPK1_ST	P29590	PML	P28482	MAPK1	T409	E405K	405	Missense	distal	-4	no	13.534	13.552	EPSD	TCGA;ICGC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P29590	PML	P28482	MAPK1	T409	P413L	413	Missense	distal	4	no	13.534	13.414	EPSD	TCGA;ICGC;COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P29590	PML	P28482	MAPK1	S505	L501F	501	Missense	distal	-4	no	13.675	13.634	EPSD	TCGA;ICGC;COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P29590	PML	P28482	MAPK1	T513	S518L	518	Missense	distal	5	no	8.109	7.878	EPSD	TCGA;ICGC;COSMIC	8.102	Loss
CMGC_MAPK_ERK1_MAPK1_ST	P29590	PML	P28482	MAPK1	S518	S518L	518	Missense	central	0	yes	14.880	0.000	EPSD	TCGA;ICGC;COSMIC	8.102	Loss
CMGC_MAPK_ERK1_MAPK1_ST	P29590	PML	P28482	MAPK1	T592	L593I	593	Missense	proximal	1	no	8.676	7.668	EPSD	TCGA	8.102	Loss
CMGC_MAPK_ERK1_MAPK1_ST	P29590	PML	P28482	MAPK1	T867	R861L	861	Missense	distal	-6	no	17.434	17.334	EPSD	TCGA;ICGC;COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q15700	DLG2	P28482	MAPK1	S360	V367L	367	Missense	distal	7	no	16.803	16.809	EPSD	TCGA;ICGC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q15700	DLG2	P28482	MAPK1	S365	V367L	367	Missense	proximal	2	no	14.400	14.306	EPSD	TCGA;ICGC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q15700	DLG2	P28482	MAPK1	S635	S635F	635	Missense	central	0	yes	8.685	0.000	EPSD	TCGA;COSMIC	8.102	Loss
CMGC_MAPK_ERK1_MAPK1_ST	Q9NRA0	SPHK2	P28482	MAPK1	S107	S111L	111	Missense	distal	4	no	14.398	14.288	EPSD	TCGA;COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q9NRA0	SPHK2	P28482	MAPK1	S107	R106C	106	Missense	proximal	-1	no	14.398	14.295	EPSD	TCGA;COSMIC;GDSC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q9NRA0	SPHK2	P28482	MAPK1	T404	D406Y	406	Missense	proximal	2	no	14.535	14.355	EPSD	TCGA;COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q9NRA0	SPHK2	P28482	MAPK1	S414	R418H	418	Missense	distal	4	no	12.711	12.569	EPSD	TCGA;COSMIC;CCLE	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q9NRA0	SPHK2	P28482	MAPK1	S473	S472F	472	Missense	proximal	-1	no	14.889	14.843	EPSD	TCGA;COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q9NRA0	SPHK2	P28482	MAPK1	S473	P467S	467	Missense	distal	-6	no	14.889	14.863	EPSD	TCGA;COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q9NRA0	SPHK2	P28482	MAPK1	S477	S472F	472	Missense	distal	-5	no	16.777	16.865	EPSD	TCGA;COSMIC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q9NRA0	SPHK2	P28482	MAPK1	S477	S484P	484	Missense	distal	7	no	16.777	16.766	EPSD	TCGA;COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q9NRA0	SPHK2	P28482	MAPK1	S484	S484P	484	Missense	central	0	yes	15.493	0.000	EPSD	TCGA;COSMIC	8.102	Loss
CMGC_MAPK_ERK1_MAPK1_ST	Q9NRA0	SPHK2	P28482	MAPK1	S487	S484P	484	Missense	distal	-3	no	8.508	8.684	EPSD	TCGA;COSMIC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q9NRA0	SPHK2	P28482	MAPK1	T503	S497C	497	Missense	distal	-6	no	13.576	13.435	EPSD	TCGA;COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q9NRA0	SPHK2	P28482	MAPK1	T503	L499F	499	Missense	distal	-4	no	13.576	13.535	EPSD	TCGA;COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q9NRA0	SPHK2	P28482	MAPK1	T503	P502S	502	Missense	proximal	-1	no	13.576	13.533	EPSD	TCGA	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q9NRA0	SPHK2	P28482	MAPK1	T641	G640S	640	Missense	proximal	-1	no	8.489	8.500	EPSD	TCGA	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P05412	JUN	P28482	MAPK1	S21	P20L	20	Missense	proximal	-1	no	8.115	8.055	EPSD	TCGA;ICGC;COSMIC	8.102	Loss
CMGC_MAPK_ERK1_MAPK1_ST	P05412	JUN	P28482	MAPK1	S21	N15I	15	Missense	distal	-6	no	8.115	8.010	EPSD	TCGA;ICGC;COSMIC	8.102	Loss
CMGC_MAPK_ERK1_MAPK1_ST	P05412	JUN	P28482	MAPK1	S21	A16T	16	Missense	distal	-5	no	8.115	8.093	EPSD	TCGA;ICGC;COSMIC	8.102	Loss
CMGC_MAPK_ERK1_MAPK1_ST	P05412	JUN	P28482	MAPK1	S21	S17L	17	Missense	distal	-4	no	8.115	7.895	EPSD	TCGA;ICGC;COSMIC	8.102	Loss
CMGC_MAPK_ERK1_MAPK1_ST	P05412	JUN	P28482	MAPK1	S73	S73L	73	Missense	central	0	yes	14.757	0.000	PhosphoSitePlus;EPSD	TCGA;ICGC;COSMIC	8.102	Loss
CMGC_MAPK_ERK1_MAPK1_ST	P05412	JUN	P28482	MAPK1	T91	G86W	86	Missense	distal	-5	no	13.961	14.217	EPSD	TCGA;ICGC;COSMIC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P05412	JUN	P28482	MAPK1	T93	G86W	86	Missense	distal	-7	no	11.641	11.603	EPSD	TCGA;ICGC;COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P05412	JUN	P28482	MAPK1	T93	C99Y	99	Missense	distal	6	no	11.641	11.889	EPSD	TCGA;ICGC;COSMIC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P05412	JUN	P28482	MAPK1	T239	P244L	244	Missense	distal	5	no	14.415	14.202	EPSD	TCGA;ICGC;COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P05412	JUN	P28482	MAPK1	S243	P244L	244	Missense	proximal	1	no	15.977	7.167	EPSD	TCGA;ICGC;COSMIC	8.102	Loss
CMGC_MAPK_ERK1_MAPK1_ST	P05412	JUN	P28482	MAPK1	T330	M323V	323	Missense	distal	-7	no	9.565	9.567	EPSD	TCGA;ICGC;COSMIC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q02750	MAP2K1	P28482	MAPK1	S18	N21T	21	Missense	distal	3	no	8.439	8.510	EPSD	TCGA	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q02750	MAP2K1	P28482	MAPK1	S25	N21T	21	Missense	distal	-4	no	9.924	9.654	EPSD	TCGA	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q02750	MAP2K1	P28482	MAPK1	S25	E31V	31	Missense	distal	6	no	9.924	9.676	EPSD	TCGA;ICGC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q02750	MAP2K1	P28482	MAPK1	T55	Q56P	56	Missense	proximal	1	no	5.492	13.986	EPSD	TCGA;ICGC;COSMIC;GDSC;CCLE	8.102	Gain
CMGC_MAPK_ERK1_MAPK1_ST	Q02750	MAP2K1	P28482	MAPK1	S231	L235H	235	Missense	distal	4	no	16.182	16.128	EPSD	TCGA;ICGC;COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q02750	MAP2K1	P28482	MAPK1	S231	S231L	231	Missense	central	0	yes	16.182	0.000	EPSD	TCGA;ICGC;COSMIC	8.102	Loss
CMGC_MAPK_ERK1_MAPK1_ST	Q02750	MAP2K1	P28482	MAPK1	S231	V224M	224	Missense	distal	-7	no	16.182	16.180	EPSD	TCGA;ICGC;COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q02750	MAP2K1	P28482	MAPK1	S231	R227K	227	Missense	distal	-4	no	16.182	16.261	EPSD	TCGA;ICGC;COSMIC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q02750	MAP2K1	P28482	MAPK1	T286	P290S	290	Missense	distal	4	no	12.915	12.904	PhosphoSitePlus;EPSD	TCGA;ICGC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q02750	MAP2K1	P28482	MAPK1	T292	G294R	294	Missense	proximal	2	no	18.747	18.842	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q02750	MAP2K1	P28482	MAPK1	T292	G294V	294	Missense	proximal	2	no	18.747	18.675	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q02750	MAP2K1	P28482	MAPK1	T292	G294E	294	Missense	proximal	2	no	18.747	18.661	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q02750	MAP2K1	P28482	MAPK1	T292	P290S	290	Missense	proximal	-2	no	18.747	15.913	EPSD;PhosphoSitePlus	TCGA;ICGC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q02750	MAP2K1	P28482	MAPK1	S299	G294R	294	Missense	distal	-5	no	9.200	9.180	EPSD	TCGA;ICGC;COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q02750	MAP2K1	P28482	MAPK1	S299	G294V	294	Missense	distal	-5	no	9.200	9.228	EPSD	TCGA;ICGC;COSMIC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q02750	MAP2K1	P28482	MAPK1	S299	G294E	294	Missense	distal	-5	no	9.200	9.157	EPSD	TCGA;ICGC;COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q02750	MAP2K1	P28482	MAPK1	S299	R305Q	305	Missense	distal	6	no	9.200	9.020	EPSD	TCGA;ICGC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q02750	MAP2K1	P28482	MAPK1	S299	D303N	303	Missense	distal	4	no	9.200	9.260	EPSD	TCGA;ICGC;COSMIC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P32004	L1CAM	P28482	MAPK1	S163	P157T	157	Missense	distal	-6	no	10.716	10.666	EPSD	TCGA;COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P32004	L1CAM	P28482	MAPK1	S163	P162L	162	Missense	proximal	-1	no	10.716	10.656	EPSD	TCGA;COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P32004	L1CAM	P28482	MAPK1	S163	P162S	162	Missense	proximal	-1	no	10.716	10.672	EPSD	TCGA;COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P32004	L1CAM	P28482	MAPK1	S611	G610E	610	Missense	proximal	-1	no	16.266	16.305	EPSD	TCGA;COSMIC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P32004	L1CAM	P28482	MAPK1	S611	L607S	607	Missense	distal	-4	no	16.266	16.486	EPSD	TCGA;COSMIC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P32004	L1CAM	P28482	MAPK1	S611	P614S	614	Missense	distal	3	no	16.266	16.335	EPSD	TCGA;COSMIC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P32004	L1CAM	P28482	MAPK1	S701	P702L	702	Missense	proximal	1	no	14.139	5.330	EPSD	TCGA;COSMIC;GDSC	8.102	Loss
CMGC_MAPK_ERK1_MAPK1_ST	P32004	L1CAM	P28482	MAPK1	S701	S704F	704	Missense	distal	3	no	14.139	14.202	EPSD	TCGA;COSMIC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P32004	L1CAM	P28482	MAPK1	T709	P702L	702	Missense	distal	-7	no	14.926	14.914	EPSD	TCGA;COSMIC;GDSC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P32004	L1CAM	P28482	MAPK1	T709	S704F	704	Missense	distal	-5	no	14.926	15.014	EPSD	TCGA;COSMIC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P32004	L1CAM	P28482	MAPK1	T709	P710T	710	Missense	proximal	1	no	14.926	6.427	EPSD	TCGA;COSMIC	8.102	Loss
CMGC_MAPK_ERK1_MAPK1_ST	P32004	L1CAM	P28482	MAPK1	T709	K716N	716	Missense	distal	7	no	14.926	14.960	EPSD	TCGA;COSMIC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P32004	L1CAM	P28482	MAPK1	S1204	D1210N	1210	Missense	distal	6	no	8.733	8.683	EPSD;PhosphoSitePlus	TCGA;COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P32004	L1CAM	P28482	MAPK1	S1204	D1206N	1206	Missense	proximal	2	no	8.733	8.673	EPSD;PhosphoSitePlus	TCGA;COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P32004	L1CAM	P28482	MAPK1	S1204	G1197E	1197	Missense	distal	-7	no	8.733	8.756	EPSD;PhosphoSitePlus	TCGA;COSMIC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P32004	L1CAM	P28482	MAPK1	S1204	D1198Y	1198	Missense	distal	-6	no	8.733	8.570	EPSD;PhosphoSitePlus	TCGA	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P32004	L1CAM	P28482	MAPK1	S1248	D1242G	1242	Missense	distal	-6	no	15.506	15.440	PhosphoSitePlus;EPSD	TCGA;COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q08499	PDE4D	P28482	MAPK1	S18	G23E	23	Missense	distal	5	no	9.011	8.986	EPSD	TCGA;ICGC;COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q08499	PDE4D	P28482	MAPK1	T25	G23E	23	Missense	proximal	-2	no	7.306	8.121	EPSD	TCGA;ICGC;COSMIC	8.102	Gain
CMGC_MAPK_ERK1_MAPK1_ST	Q08499	PDE4D	P28482	MAPK1	S164	M169T	169	Missense	distal	5	no	13.051	13.182	EPSD	TCGA;ICGC;COSMIC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q08499	PDE4D	P28482	MAPK1	S164	G158S	158	Missense	distal	-6	no	13.051	13.068	EPSD	TCGA;ICGC;COSMIC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q08499	PDE4D	P28482	MAPK1	S164	P165S	165	Missense	proximal	1	no	13.051	3.656	EPSD	TCGA;ICGC;COSMIC	8.102	Loss
CMGC_MAPK_ERK1_MAPK1_ST	Q08499	PDE4D	P28482	MAPK1	S164	A161V	161	Missense	distal	-3	no	13.051	13.111	EPSD	TCGA;ICGC;COSMIC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q08499	PDE4D	P28482	MAPK1	S164	R163W	163	Missense	proximal	-1	no	13.051	12.950	EPSD	TCGA;ICGC;COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q08499	PDE4D	P28482	MAPK1	S164	R163Q	163	Missense	proximal	-1	no	13.051	13.030	EPSD	TCGA;ICGC;COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q08499	PDE4D	P28482	MAPK1	S171	M169T	169	Missense	proximal	-2	no	13.993	15.308	EPSD	TCGA;ICGC;COSMIC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q08499	PDE4D	P28482	MAPK1	S171	P165S	165	Missense	distal	-6	no	13.993	13.967	EPSD	TCGA;ICGC;COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q08499	PDE4D	P28482	MAPK1	S171	S174F	174	Missense	distal	3	no	13.993	14.056	EPSD	TCGA;ICGC;COSMIC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q08499	PDE4D	P28482	MAPK1	S202	S195T	195	Missense	distal	-7	no	12.862	12.849	EPSD	TCGA;ICGC;COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q08499	PDE4D	P28482	MAPK1	S202	S207P	207	Missense	distal	5	no	12.862	12.844	EPSD	TCGA	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q08499	PDE4D	P28482	MAPK1	S202	D196N	196	Missense	distal	-6	no	12.862	12.816	EPSD	TCGA;ICGC;COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q08499	PDE4D	P28482	MAPK1	T224	G218R	218	Missense	distal	-6	no	16.153	16.204	EPSD	TCGA;ICGC;COSMIC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q08499	PDE4D	P28482	MAPK1	T224	G218E	218	Missense	distal	-6	no	16.153	16.207	EPSD	TCGA;ICGC;COSMIC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q08499	PDE4D	P28482	MAPK1	S255	N259K	259	Missense	distal	4	no	14.149	14.173	EPSD	TCGA;ICGC;COSMIC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q08499	PDE4D	P28482	MAPK1	S255	S262T	262	Missense	distal	7	no	14.149	14.301	EPSD	TCGA	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q08499	PDE4D	P28482	MAPK1	S348	T350S	350	Missense	proximal	2	no	14.264	14.287	EPSD	TCGA;ICGC;COSMIC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q08499	PDE4D	P28482	MAPK1	S348	K354N	354	Missense	distal	6	no	14.264	14.111	EPSD	TCGA;ICGC;COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q08499	PDE4D	P28482	MAPK1	S657	D661N	661	Missense	distal	4	no	12.270	12.330	EPSD	TCGA;ICGC;COSMIC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q08499	PDE4D	P28482	MAPK1	S657	C660F	660	Missense	distal	3	no	12.270	12.229	EPSD	TCGA;ICGC;COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q08499	PDE4D	P28482	MAPK1	S806	R805H	805	Missense	proximal	-1	no	15.209	15.185	EPSD	TCGA;ICGC;COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q08499	PDE4D	P28482	MAPK1	S806	R805C	805	Missense	proximal	-1	no	15.209	15.106	EPSD	TCGA;ICGC;COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q08499	PDE4D	P28482	MAPK1	S806	V801G	801	Missense	distal	-5	no	15.209	15.180	EPSD	TCGA;ICGC;COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q3V6T2	CCDC88A	P28482	MAPK1	S16	Q12H	12	Missense	distal	-4	no	13.968	13.919	EPSD	TCGA;ICGC;COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q3V6T2	CCDC88A	P28482	MAPK1	S233	H226Y	226	Missense	distal	-7	no	13.645	13.626	PhosphoSitePlus;EPSD	TCGA;ICGC;COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q3V6T2	CCDC88A	P28482	MAPK1	S1675	H1668Y	1668	Missense	distal	-7	no	13.899	13.880	EPSD	TCGA;ICGC;COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q3V6T2	CCDC88A	P28482	MAPK1	S1675	H1668R	1668	Missense	distal	-7	no	13.899	13.910	EPSD	TCGA;ICGC;COSMIC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q3V6T2	CCDC88A	P28482	MAPK1	T1774	S1768Y	1768	Missense	distal	-6	no	15.131	15.016	EPSD	TCGA;COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q9ULV5	HSF4	P28482	MAPK1	S298	G300E	300	Missense	proximal	2	no	16.871	16.786	PhosphoSitePlus	TCGA;ICGC;COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q9ULV5	HSF4	P28482	MAPK1	S298	E304K	304	Missense	distal	6	no	16.871	16.895	PhosphoSitePlus	TCGA;ICGC;COSMIC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q9ULV5	HSF4	P28482	MAPK1	S298	A297T	297	Missense	proximal	-1	no	16.871	16.866	PhosphoSitePlus	TCGA;ICGC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q9ULV5	HSF4	P28482	MAPK1	S298	A297V	297	Missense	proximal	-1	no	16.871	16.882	PhosphoSitePlus	TCGA;ICGC;COSMIC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q9ULV5	HSF4	P28482	MAPK1	S298	P296L	296	Missense	proximal	-2	no	16.871	14.954	PhosphoSitePlus	TCGA;ICGC;COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q9ULV5	HSF4	P28482	MAPK1	S298	A305V	305	Missense	distal	7	no	16.871	16.973	PhosphoSitePlus	TCGA;ICGC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q9ULV5	HSF4	P28482	MAPK1	S340	S338R	338	Missense	proximal	-2	no	12.390	13.406	EPSD	TCGA;ICGC;COSMIC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q9ULV5	HSF4	P28482	MAPK1	S340	S340I	340	Missense	central	0	yes	12.390	0.000	EPSD	TCGA;ICGC;COSMIC	8.102	Loss
CMGC_MAPK_ERK1_MAPK1_ST	Q9ULV5	HSF4	P28482	MAPK1	S340	E342G	342	Missense	proximal	2	no	12.390	12.476	EPSD	TCGA;ICGC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q9ULV5	HSF4	P28482	MAPK1	S489	S491F	491	Missense	proximal	2	no	16.283	16.151	EPSD	TCGA;ICGC;COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q9ULV5	HSF4	P28482	MAPK1	S489	S491P	491	Missense	proximal	2	no	16.283	16.310	EPSD	TCGA;COSMIC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q9ULV5	HSF4	P28482	MAPK1	S489	S489G	489	Missense	central	0	yes	16.283	0.000	EPSD	TCGA;ICGC;COSMIC	8.102	Loss
CMGC_MAPK_ERK1_MAPK1_ST	Q9ULV5	HSF4	P28482	MAPK1	S491	S491F	491	Missense	central	0	yes	16.331	0.000	EPSD	TCGA;ICGC;COSMIC	8.102	Loss
CMGC_MAPK_ERK1_MAPK1_ST	Q9ULV5	HSF4	P28482	MAPK1	S491	S491P	491	Missense	central	0	yes	16.331	0.000	EPSD	TCGA;COSMIC	8.102	Loss
CMGC_MAPK_ERK1_MAPK1_ST	Q9ULV5	HSF4	P28482	MAPK1	S491	S489G	489	Missense	proximal	-2	no	16.331	15.971	EPSD	TCGA;ICGC;COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q9Y463	DYRK1B	P28482	MAPK1	S276	R277H	277	Missense	proximal	1	no	6.725	8.556	EPSD	TCGA;ICGC;COSMIC	8.102	Gain
CMGC_MAPK_ERK1_MAPK1_ST	Q9Y463	DYRK1B	P28482	MAPK1	S421	A425V	425	Missense	distal	4	no	12.419	12.413	PhosphoSitePlus	TCGA;COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q9Y463	DYRK1B	P28482	MAPK1	S451	C458Y	458	Missense	distal	7	no	14.029	13.888	EPSD	TCGA;COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q9Y463	DYRK1B	P28482	MAPK1	S554	L549F	549	Missense	distal	-5	no	17.752	17.766	EPSD	TCGA;COSMIC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q9Y463	DYRK1B	P28482	MAPK1	S576	A583S	583	Missense	distal	7	no	15.067	14.886	EPSD	TCGA;COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q9Y463	DYRK1B	P28482	MAPK1	S576	A583T	583	Missense	distal	7	no	15.067	15.038	EPSD	TCGA;COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q8N122	RPTOR	P28482	MAPK1	S8	L10F	10	Missense	proximal	2	no	13.924	13.912	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q8N122	RPTOR	P28482	MAPK1	S8	L11M	11	Missense	distal	3	no	13.924	13.919	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q8N122	RPTOR	P28482	MAPK1	T706	C713F	713	Missense	distal	7	no	13.957	13.645	EPSD	TCGA	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q8N122	RPTOR	P28482	MAPK1	T706	R709Q	709	Missense	distal	3	no	13.957	13.979	EPSD	TCGA;COSMIC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q8N122	RPTOR	P28482	MAPK1	S711	C713F	713	Missense	proximal	2	no	15.912	16.012	EPSD	TCGA	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q8N122	RPTOR	P28482	MAPK1	S711	R709Q	709	Missense	proximal	-2	no	15.912	14.737	EPSD	TCGA;COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q8N122	RPTOR	P28482	MAPK1	T714	S719F	719	Missense	distal	5	no	16.181	15.984	EPSD	TCGA;ICGC;COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q8N122	RPTOR	P28482	MAPK1	T714	C713F	713	Missense	proximal	-1	no	16.181	16.213	EPSD	TCGA	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q8N122	RPTOR	P28482	MAPK1	T714	R709Q	709	Missense	distal	-5	no	16.181	16.258	EPSD	TCGA;COSMIC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q8N122	RPTOR	P28482	MAPK1	S722	S719F	719	Missense	distal	-3	no	8.137	7.905	EPSD	TCGA;ICGC;COSMIC	8.102	Loss
CMGC_MAPK_ERK1_MAPK1_ST	Q8N122	RPTOR	P28482	MAPK1	S722	Y723C	723	Missense	proximal	1	no	8.137	1.698	EPSD	TCGA;COSMIC	8.102	Loss
CMGC_MAPK_ERK1_MAPK1_ST	Q8N122	RPTOR	P28482	MAPK1	S722	G724E	724	Missense	proximal	2	no	8.137	8.051	EPSD	TCGA;COSMIC	8.102	Loss
CMGC_MAPK_ERK1_MAPK1_ST	Q8N122	RPTOR	P28482	MAPK1	S771	E775K	775	Missense	distal	4	no	14.514	14.528	EPSD	TCGA;COSMIC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q8N122	RPTOR	P28482	MAPK1	T809	Q810H	810	Missense	proximal	1	no	7.736	8.405	EPSD	TCGA;COSMIC	8.102	Gain
CMGC_MAPK_ERK1_MAPK1_ST	Q8N122	RPTOR	P28482	MAPK1	T809	L815P	815	Missense	distal	6	no	7.736	8.142	EPSD	TCGA;COSMIC	8.102	Gain
CMGC_MAPK_ERK1_MAPK1_ST	Q8N122	RPTOR	P28482	MAPK1	S863	T857M	857	Missense	distal	-6	no	15.667	15.633	EPSD;PhosphoSitePlus	TCGA;COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q8N122	RPTOR	P28482	MAPK1	S877	S877F	877	Missense	central	0	yes	14.703	0.000	EPSD	TCGA;COSMIC	8.102	Loss
CMGC_MAPK_ERK1_MAPK1_ST	Q8N122	RPTOR	P28482	MAPK1	S877	P879L	879	Missense	proximal	2	no	14.703	14.555	EPSD	TCGA;COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q8N122	RPTOR	P28482	MAPK1	S881	S877F	877	Missense	distal	-4	no	8.691	8.430	EPSD	TCGA;COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q8N122	RPTOR	P28482	MAPK1	S881	P879L	879	Missense	proximal	-2	no	8.691	6.773	EPSD	TCGA;COSMIC	8.102	Loss
CMGC_MAPK_ERK1_MAPK1_ST	Q8N122	RPTOR	P28482	MAPK1	S920	R927L	927	Missense	distal	7	no	8.381	8.666	EPSD	TCGA;COSMIC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P49407	ARRB1	P28482	MAPK1	T275	N281K	281	Missense	distal	6	no	11.183	11.336	EPSD	TCGA;ICGC;COSMIC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P49407	ARRB1	P28482	MAPK1	T275	C269Y	269	Missense	distal	-6	no	11.183	11.210	EPSD	TCGA;ICGC;COSMIC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q53EZ4	CEP55	P28482	MAPK1	T25	S23F	23	Missense	proximal	-2	no	7.949	8.142	EPSD	TCGA;ICGC;COSMIC	8.102	Gain
CMGC_MAPK_ERK1_MAPK1_ST	Q53EZ4	CEP55	P28482	MAPK1	T26	L27F	27	Missense	proximal	1	no	7.929	10.169	EPSD	TCGA;ICGC;COSMIC	8.102	Gain
CMGC_MAPK_ERK1_MAPK1_ST	Q53EZ4	CEP55	P28482	MAPK1	S436	L437P	437	Missense	proximal	1	no	5.144	13.953	EPSD	TCGA;ICGC;COSMIC	8.102	Gain
CMGC_MAPK_ERK1_MAPK1_ST	P31645	SLC6A4	P28482	MAPK1	S52	D58N	58	Missense	distal	6	no	16.017	15.966	EPSD	TCGA;ICGC;COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P31645	SLC6A4	P28482	MAPK1	S52	A55T	55	Missense	distal	3	no	16.017	16.000	EPSD	TCGA;ICGC;COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P31645	SLC6A4	P28482	MAPK1	S52	A55V	55	Missense	distal	3	no	16.017	15.996	EPSD	TCGA;ICGC;COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P31645	SLC6A4	P28482	MAPK1	S559	L557P	557	Missense	proximal	-2	no	16.774	18.692	EPSD	TCGA;ICGC;COSMIC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P31645	SLC6A4	P28482	MAPK1	T603	P601L	601	Missense	proximal	-2	no	10.040	8.123	EPSD	TCGA;ICGC;COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P31645	SLC6A4	P28482	MAPK1	T603	R596Q	596	Missense	distal	-7	no	10.040	10.048	EPSD	TCGA;ICGC;COSMIC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P31645	SLC6A4	P28482	MAPK1	T603	R607C	607	Missense	distal	4	no	10.040	9.781	EPSD	TCGA;ICGC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P31645	SLC6A4	P28482	MAPK1	T603	R596W	596	Missense	distal	-7	no	10.040	9.989	EPSD	TCGA;ICGC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P31645	SLC6A4	P28482	MAPK1	T613	R607C	607	Missense	distal	-6	no	15.011	14.836	EPSD	TCGA;ICGC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P33076	CIITA	P28482	MAPK1	S280	R283Q	283	Missense	distal	3	no	16.876	16.898	PhosphoSitePlus;EPSD	TCGA;COSMIC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P33076	CIITA	P28482	MAPK1	S280	P281A	281	Missense	proximal	1	no	16.876	9.246	PhosphoSitePlus;EPSD	TCGA;COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P33076	CIITA	P28482	MAPK1	S280	T273I	273	Missense	distal	-7	no	16.876	16.861	PhosphoSitePlus;EPSD	TCGA;COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P33076	CIITA	P28482	MAPK1	S288	R283Q	283	Missense	distal	-5	no	12.958	13.035	EPSD;PhosphoSitePlus	TCGA;COSMIC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P33076	CIITA	P28482	MAPK1	S288	P281A	281	Missense	distal	-7	no	12.958	12.956	EPSD;PhosphoSitePlus	TCGA;COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P33076	CIITA	P28482	MAPK1	S834	T841M	841	Missense	distal	7	no	8.103	8.310	EPSD	TCGA	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P33076	CIITA	P28482	MAPK1	S834	R832H	832	Missense	proximal	-2	no	8.103	7.166	EPSD	TCGA;ICGC	8.102	Loss
CMGC_MAPK_ERK1_MAPK1_ST	P78347	GTF2I	P28482	MAPK1	T24	R20S	20	Missense	distal	-4	no	9.420	9.425	EPSD	TCGA;ICGC;COSMIC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P78347	GTF2I	P28482	MAPK1	T24	L30V	30	Missense	distal	6	no	9.420	9.611	EPSD	TCGA;ICGC;COSMIC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P78347	GTF2I	P28482	MAPK1	T24	E18K	18	Missense	distal	-6	no	9.420	9.394	EPSD	TCGA;ICGC;COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P78347	GTF2I	P28482	MAPK1	T24	A29D	29	Missense	distal	5	no	9.420	9.604	EPSD	TCGA;ICGC;COSMIC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P78347	GTF2I	P28482	MAPK1	T24	S28L	28	Missense	distal	4	no	9.420	9.310	EPSD	TCGA;ICGC;COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P78347	GTF2I	P28482	MAPK1	S210	P211A	211	Missense	proximal	1	no	15.139	7.509	EPSD	TCGA;ICGC;COSMIC	8.102	Loss
CMGC_MAPK_ERK1_MAPK1_ST	P78347	GTF2I	P28482	MAPK1	T558	R555I	555	Missense	distal	-3	no	12.836	12.414	EPSD	TCGA;COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P78347	GTF2I	P28482	MAPK1	S620	R619Q	619	Missense	proximal	-1	no	11.425	11.403	EPSD	TCGA;COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P78347	GTF2I	P28482	MAPK1	S620	P617S	617	Missense	distal	-3	no	11.425	11.248	EPSD	TCGA;COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P78347	GTF2I	P28482	MAPK1	S651	I650F	650	Missense	proximal	-1	no	9.846	9.822	EPSD	TCGA;COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P78347	GTF2I	P28482	MAPK1	S971	E969Q	969	Missense	proximal	-2	no	9.785	9.171	EPSD	TCGA	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q14790	CASP8	P28482	MAPK1	S16	E12K	12	Missense	distal	-4	no	8.781	8.800	EPSD	TCGA;ICGC;COSMIC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q14790	CASP8	P28482	MAPK1	S60	L66V	66	Missense	distal	6	no	8.126	8.317	EPSD	TCGA;COSMIC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q14790	CASP8	P28482	MAPK1	S60	L66R	66	Missense	distal	6	no	8.126	8.425	EPSD	TCGA;COSMIC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q14790	CASP8	P28482	MAPK1	T373	S375F	375	Missense	proximal	2	no	8.624	8.492	EPSD	TCGA;COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P28482	MAPK1	P28482	MAPK1	S29	G34C	34	Missense	distal	5	no	8.276	7.895	EPSD	TCGA;ICGC;COSMIC;CCLE	8.102	Loss
CMGC_MAPK_ERK1_MAPK1_ST	P28482	MAPK1	P28482	MAPK1	S142	H147R	147	Missense	distal	5	no	8.024	8.200	EPSD	TCGA;ICGC	8.102	Gain
CMGC_MAPK_ERK1_MAPK1_ST	P28482	MAPK1	P28482	MAPK1	T185	D179G	179	Missense	distal	-6	no	8.330	8.264	EPSD	TCGA	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P28482	MAPK1	P28482	MAPK1	T185	R191C	191	Missense	distal	6	no	8.330	7.570	EPSD	TCGA;ICGC;COSMIC	8.102	Loss
CMGC_MAPK_ERK1_MAPK1_ST	P28482	MAPK1	P28482	MAPK1	T185	R191H	191	Missense	distal	6	no	8.330	8.132	EPSD	TCGA;ICGC;COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P28482	MAPK1	P28482	MAPK1	T190	R191H	191	Missense	proximal	1	no	7.918	9.749	EPSD	TCGA;ICGC;COSMIC	8.102	Gain
CMGC_MAPK_ERK1_MAPK1_ST	P28482	MAPK1	P28482	MAPK1	S246	L244F	244	Missense	proximal	-2	no	15.872	15.148	PhosphoSitePlus	TCGA;ICGC;COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P37231	PPARG	P28482	MAPK1	S112	S117Y	117	Missense	distal	5	no	18.041	17.752	PhosphoSitePlus	TCGA	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P37231	PPARG	P28482	MAPK1	S273	M280T	280	Missense	distal	7	no	11.631	11.423	EPSD	TCGA;COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P37231	PPARG	P28482	MAPK1	S273	G267E	267	Missense	distal	-6	no	11.631	11.685	EPSD	TCGA	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	O43521	BCL2L11	P28482	MAPK1	S59	P63S	63	Missense	distal	4	no	13.276	13.265	EPSD	TCGA;ICGC;COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	O43521	BCL2L11	P28482	MAPK1	S69	P63S	63	Missense	distal	-6	no	15.383	15.357	PhosphoSitePlus	TCGA;ICGC;COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	O43521	BCL2L11	P28482	MAPK1	S69	A68V	68	Missense	proximal	-1	no	15.383	15.394	PhosphoSitePlus	TCGA;ICGC;COSMIC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	O43521	BCL2L11	P28482	MAPK1	S77	S77F	77	Missense	central	0	yes	14.223	0.000	EPSD	TCGA;ICGC;COSMIC	8.102	Loss
CMGC_MAPK_ERK1_MAPK1_ST	O43521	BCL2L11	P28482	MAPK1	S77	R84T	84	Missense	distal	7	no	14.223	14.372	EPSD	TCGA;ICGC;COSMIC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	O43521	BCL2L11	P28482	MAPK1	S98	R91Q	91	Missense	distal	-7	no	8.256	8.265	EPSD	TCGA;ICGC;COSMIC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	O43521	BCL2L11	P28482	MAPK1	S98	Y96C	96	Missense	proximal	-2	no	8.256	6.607	EPSD	TCGA;ICGC;COSMIC	8.102	Loss
CMGC_MAPK_ERK1_MAPK1_ST	P42229	STAT5A	P28482	MAPK1	S128	E122Q	122	Missense	distal	-6	no	13.396	13.370	EPSD	TCGA;ICGC;COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P42229	STAT5A	P28482	MAPK1	S128	D135E	135	Missense	distal	7	no	13.396	13.341	EPSD	TCGA;COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P42229	STAT5A	P28482	MAPK1	S193	A187S	187	Missense	distal	-6	no	13.717	13.730	EPSD	TCGA;COSMIC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P42229	STAT5A	P28482	MAPK1	S777	R778H	778	Missense	proximal	1	no	7.624	9.455	EPSD	TCGA;COSMIC	8.102	Gain
CMGC_MAPK_ERK1_MAPK1_ST	P42229	STAT5A	P28482	MAPK1	S780	R778H	778	Missense	proximal	-2	no	19.102	18.165	PhosphoSitePlus	TCGA;COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P42229	STAT5A	P28482	MAPK1	S780	D776G	776	Missense	distal	-4	no	19.102	18.766	PhosphoSitePlus	TCGA;COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q15366	PCBP2	P28482	MAPK1	S173	P175L	175	Missense	proximal	2	no	13.695	13.547	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q15366	PCBP2	P28482	MAPK1	S173	L170I	170	Missense	distal	-3	no	13.695	13.637	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q15366	PCBP2	P28482	MAPK1	S173	P175T	175	Missense	proximal	2	no	13.695	13.644	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q15366	PCBP2	P28482	MAPK1	S208	G203D	203	Missense	distal	-5	no	9.677	9.680	EPSD	TCGA;ICGC;COSMIC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q15366	PCBP2	P28482	MAPK1	T213	P220H	220	Missense	distal	7	no	12.889	13.123	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q15366	PCBP2	P28482	MAPK1	S272	I268T	268	Missense	distal	-4	no	14.683	15.041	PhosphoSitePlus;EPSD	TCGA;COSMIC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q8N9N5	BANP	P28482	MAPK1	S19	D17Y	17	Missense	proximal	-2	no	16.260	17.444	EPSD	TCGA;ICGC;COSMIC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q8N9N5	BANP	P28482	MAPK1	S19	L18M	18	Missense	proximal	-1	no	16.260	16.270	EPSD	TCGA;ICGC;COSMIC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q8N9N5	BANP	P28482	MAPK1	S90	P95S	95	Missense	distal	5	no	12.929	12.947	EPSD	TCGA;COSMIC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q8N9N5	BANP	P28482	MAPK1	S90	Q93H	93	Missense	distal	3	no	12.929	12.950	EPSD	TCGA;COSMIC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q8N9N5	BANP	P28482	MAPK1	S90	V84I	84	Missense	distal	-6	no	12.929	12.888	EPSD	TCGA	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q8N9N5	BANP	P28482	MAPK1	S100	P95S	95	Missense	distal	-5	no	14.601	14.675	EPSD	TCGA;COSMIC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q8N9N5	BANP	P28482	MAPK1	S100	G99V	99	Missense	proximal	-1	no	14.601	14.629	EPSD	TCGA;COSMIC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q8N9N5	BANP	P28482	MAPK1	S100	Q93H	93	Missense	distal	-7	no	14.601	14.582	EPSD	TCGA;COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q8N9N5	BANP	P28482	MAPK1	S334	R335W	335	Missense	proximal	1	no	6.816	9.094	EPSD	TCGA;COSMIC	8.102	Gain
CMGC_MAPK_ERK1_MAPK1_ST	Q8N9N5	BANP	P28482	MAPK1	T337	S340L	340	Missense	distal	3	no	15.315	15.335	PhosphoSitePlus;EPSD	TCGA	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q8N9N5	BANP	P28482	MAPK1	T337	S341F	341	Missense	distal	4	no	15.315	15.137	PhosphoSitePlus;EPSD	TCGA;COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q8N9N5	BANP	P28482	MAPK1	T337	R335W	335	Missense	proximal	-2	no	15.315	14.391	PhosphoSitePlus;EPSD	TCGA;COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q8N9N5	BANP	P28482	MAPK1	T337	N339S	339	Missense	proximal	2	no	15.315	15.363	PhosphoSitePlus;EPSD	TCGA	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q8N9N5	BANP	P28482	MAPK1	T352	P348L	348	Missense	distal	-4	no	12.550	12.246	EPSD;PhosphoSitePlus	TCGA;COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q8N9N5	BANP	P28482	MAPK1	T352	P353S	353	Missense	proximal	1	no	12.550	3.155	EPSD;PhosphoSitePlus	TCGA;COSMIC	8.102	Loss
CMGC_MAPK_ERK1_MAPK1_ST	Q8N9N5	BANP	P28482	MAPK1	T352	P355S	355	Missense	distal	3	no	12.550	12.619	EPSD;PhosphoSitePlus	TCGA;COSMIC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q8N9N5	BANP	P28482	MAPK1	T352	T352A	352	Missense	central	0	yes	12.550	0.000	EPSD;PhosphoSitePlus	TCGA;COSMIC	8.102	Loss
CMGC_MAPK_ERK1_MAPK1_ST	Q8N9N5	BANP	P28482	MAPK1	T352	A356T	356	Missense	distal	4	no	12.550	12.530	EPSD;PhosphoSitePlus	TCGA;COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q8N9N5	BANP	P28482	MAPK1	T352	T352I	352	Missense	central	0	yes	12.550	0.000	EPSD;PhosphoSitePlus	TCGA	8.102	Loss
CMGC_MAPK_ERK1_MAPK1_ST	O00429	DNM1L	P28482	MAPK1	S330	S330N	330	Missense	central	0	yes	8.269	0.000	EPSD	TCGA;COSMIC	8.102	Loss
CMGC_MAPK_ERK1_MAPK1_ST	O00429	DNM1L	P28482	MAPK1	S330	V326A	326	Missense	distal	-4	no	8.269	8.330	EPSD	TCGA	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	O00429	DNM1L	P28482	MAPK1	S412	S412L	412	Missense	central	0	yes	10.268	0.000	EPSD	TCGA;COSMIC	8.102	Loss
CMGC_MAPK_ERK1_MAPK1_ST	O00429	DNM1L	P28482	MAPK1	S526	S533F	533	Missense	distal	7	no	8.336	8.683	EPSD	TCGA;ICGC;COSMIC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	O00429	DNM1L	P28482	MAPK1	S526	R522K	522	Missense	distal	-4	no	8.336	8.414	EPSD	TCGA;COSMIC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	O00429	DNM1L	P28482	MAPK1	S526	R519M	519	Missense	distal	-7	no	8.336	8.319	EPSD	TCGA;COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	O00429	DNM1L	P28482	MAPK1	S616	A622V	622	Missense	distal	6	no	14.544	14.626	PhosphoSitePlus	TCGA;COSMIC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	O00429	DNM1L	P28482	MAPK1	S616	G620C	620	Missense	distal	4	no	14.544	14.312	PhosphoSitePlus	TCGA	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q5T447	HECTD3	P28482	MAPK1	T157	Q164R	164	Missense	distal	7	no	15.947	15.832	PhosphoSitePlus	TCGA;ICGC;COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q5T447	HECTD3	P28482	MAPK1	S857	D853N	853	Missense	distal	-4	no	17.229	17.201	EPSD	TCGA;COSMIC;GDSC;CCLE	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q5T447	HECTD3	P28482	MAPK1	S857	V850M	850	Missense	distal	-7	no	17.229	17.227	EPSD	TCGA;COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P00533	EGFR	P28482	MAPK1	S227	R222C	222	Missense	distal	-5	no	13.009	13.239	EPSD	TCGA;COSMIC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P00533	EGFR	P28482	MAPK1	S227	S229C	229	Missense	proximal	2	no	13.009	12.777	EPSD	TCGA;COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P00533	EGFR	P28482	MAPK1	S227	C223Y	223	Missense	distal	-4	no	13.009	13.064	EPSD	TCGA;COSMIC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P00533	EGFR	P28482	MAPK1	S227	R222L	222	Missense	distal	-5	no	13.009	13.111	EPSD	TCGA;COSMIC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P00533	EGFR	P28482	MAPK1	S227	S227F	227	Missense	central	0	yes	13.009	0.000	EPSD	TCGA;COSMIC	8.102	Loss
CMGC_MAPK_ERK1_MAPK1_ST	P00533	EGFR	P28482	MAPK1	S227	P228L	228	Missense	proximal	1	no	13.009	4.199	EPSD	TCGA;COSMIC	8.102	Loss
CMGC_MAPK_ERK1_MAPK1_ST	P00533	EGFR	P28482	MAPK1	S227	N234S	234	Missense	distal	7	no	13.009	13.026	EPSD	TCGA;COSMIC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P00533	EGFR	P28482	MAPK1	S227	R224H	224	Missense	distal	-3	no	13.009	12.679	EPSD	TCGA;COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P00533	EGFR	P28482	MAPK1	S511	P512S	512	Missense	proximal	1	no	13.698	4.303	EPSD	TCGA;COSMIC	8.102	Loss
CMGC_MAPK_ERK1_MAPK1_ST	P00533	EGFR	P28482	MAPK1	T693	P699L	699	Missense	distal	6	no	16.959	16.553	PhosphoSitePlus	TCGA;COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P00533	EGFR	P28482	MAPK1	S752	I759N	759	Missense	distal	7	no	15.051	14.486	EPSD	TCGA;COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P00533	EGFR	P28482	MAPK1	S752	K754I	754	Missense	proximal	2	no	15.051	14.948	EPSD	TCGA;COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P00533	EGFR	P28482	MAPK1	S752	P753L	753	Missense	proximal	1	no	15.051	6.241	EPSD	TCGA;COSMIC	8.102	Loss
CMGC_MAPK_ERK1_MAPK1_ST	P00533	EGFR	P28482	MAPK1	S752	P753S	753	Missense	proximal	1	no	15.051	5.656	EPSD	TCGA;COSMIC;GDSC;CCLE	8.102	Loss
CMGC_MAPK_ERK1_MAPK1_ST	P00533	EGFR	P28482	MAPK1	S991	F997V	997	Missense	distal	6	no	14.909	15.135	EPSD	TCGA;COSMIC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P00533	EGFR	P28482	MAPK1	S1026	T1032S	1032	Missense	distal	6	no	13.873	14.083	EPSD	TCGA;COSMIC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P00533	EGFR	P28482	MAPK1	S1026	P1019L	1019	Missense	distal	-7	no	13.873	13.861	EPSD	TCGA;COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P00533	EGFR	P28482	MAPK1	S1026	R1031Q	1031	Missense	distal	5	no	13.873	13.703	EPSD	TCGA;COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P00533	EGFR	P28482	MAPK1	T1032	R1031Q	1031	Missense	proximal	-1	no	12.261	12.240	EPSD	TCGA;COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P00533	EGFR	P28482	MAPK1	S1039	T1032S	1032	Missense	distal	-7	no	8.103	8.116	EPSD	TCGA;COSMIC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P00533	EGFR	P28482	MAPK1	S1039	S1042N	1042	Missense	distal	3	no	8.103	8.025	EPSD	TCGA;COSMIC	8.102	Loss
CMGC_MAPK_ERK1_MAPK1_ST	P00533	EGFR	P28482	MAPK1	T1085	E1079K	1079	Missense	distal	-6	no	8.248	8.222	EPSD	TCGA;COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P00533	EGFR	P28482	MAPK1	T1085	D1084N	1084	Missense	proximal	-1	no	8.248	8.309	EPSD	TCGA	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P00533	EGFR	P28482	MAPK1	S1130	P1123S	1123	Missense	distal	-7	no	8.862	8.858	EPSD	TCGA;ICGC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P00533	EGFR	P28482	MAPK1	S1153	D1152N	1152	Missense	proximal	-1	no	14.713	14.775	EPSD	TCGA;ICGC;COSMIC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P00533	EGFR	P28482	MAPK1	S1153	T1150S	1150	Missense	distal	-3	no	14.713	14.746	EPSD	TCGA;ICGC;COSMIC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P00533	EGFR	P28482	MAPK1	S1153	F1151L	1151	Missense	proximal	-2	no	14.713	15.437	EPSD	TCGA;ICGC;COSMIC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P00533	EGFR	P28482	MAPK1	S1153	V1147A	1147	Missense	distal	-6	no	14.713	14.761	EPSD	TCGA;ICGC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P00533	EGFR	P28482	MAPK1	S1204	A1201V	1201	Missense	distal	-3	no	9.983	10.043	EPSD	TCGA;ICGC;COSMIC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P00533	EGFR	P28482	MAPK1	S1205	A1201V	1201	Missense	distal	-4	no	8.412	8.351	EPSD	TCGA;ICGC;COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P14635	CCNB1	P28482	MAPK1	S116	S116L	116	Missense	central	0	yes	15.847	0.000	EPSD	TCGA;ICGC;COSMIC	8.102	Loss
CMGC_MAPK_ERK1_MAPK1_ST	P14635	CCNB1	P28482	MAPK1	S126	T124S	124	Missense	proximal	-2	no	13.302	13.167	PhosphoSitePlus;EPSD	TCGA;ICGC;COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P14635	CCNB1	P28482	MAPK1	S126	M130V	130	Missense	distal	4	no	13.302	13.391	PhosphoSitePlus;EPSD	TCGA;ICGC;COSMIC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P14635	CCNB1	P28482	MAPK1	S126	T132I	132	Missense	distal	6	no	13.302	12.845	PhosphoSitePlus;EPSD	TCGA;ICGC;COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P14635	CCNB1	P28482	MAPK1	S128	T124S	124	Missense	distal	-4	no	14.397	14.626	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P14635	CCNB1	P28482	MAPK1	S128	M130V	130	Missense	proximal	2	no	14.397	14.534	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P14635	CCNB1	P28482	MAPK1	S128	T132I	132	Missense	distal	4	no	14.397	14.344	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P14635	CCNB1	P28482	MAPK1	T362	H367Y	367	Missense	distal	5	no	11.836	11.693	EPSD	TCGA;ICGC;COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q9H9S0	NANOG	P28482	MAPK1	S52	M58I	58	Missense	distal	6	no	10.829	10.595	PhosphoSitePlus;EPSD	TCGA;ICGC;COSMIC;CCLE	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q9H9S0	NANOG	P28482	MAPK1	S52	T50N	50	Missense	proximal	-2	no	10.829	10.708	PhosphoSitePlus;EPSD	TCGA;ICGC;COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q9H9S0	NANOG	P28482	MAPK1	S52	P55S	55	Missense	distal	3	no	10.829	10.898	PhosphoSitePlus;EPSD	TCGA;ICGC;COSMIC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q9H9S0	NANOG	P28482	MAPK1	S52	P53L	53	Missense	proximal	1	no	10.829	2.019	PhosphoSitePlus;EPSD	TCGA;ICGC;COSMIC	8.102	Loss
CMGC_MAPK_ERK1_MAPK1_ST	Q9H9S0	NANOG	P28482	MAPK1	S52	L54F	54	Missense	proximal	2	no	10.829	10.817	PhosphoSitePlus;EPSD	TCGA;ICGC;COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q9H9S0	NANOG	P28482	MAPK1	S65	M58I	58	Missense	distal	-7	no	15.041	15.030	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC;CCLE	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q9H9S0	NANOG	P28482	MAPK1	S65	S68Y	68	Missense	distal	3	no	15.041	15.099	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q9H9S0	NANOG	P28482	MAPK1	S71	T78I	78	Missense	distal	7	no	11.627	12.023	EPSD	TCGA;ICGC;COSMIC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q9H9S0	NANOG	P28482	MAPK1	S71	S68Y	68	Missense	distal	-3	no	11.627	11.358	EPSD	TCGA;ICGC;COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q9H9S0	NANOG	P28482	MAPK1	S79	A80V	80	Missense	proximal	1	no	9.400	7.489	EPSD	TCGA;ICGC;COSMIC	8.102	Loss
CMGC_MAPK_ERK1_MAPK1_ST	Q9H9S0	NANOG	P28482	MAPK1	S79	T78I	78	Missense	proximal	-1	no	9.400	9.376	EPSD	TCGA;ICGC;COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q9H9S0	NANOG	P28482	MAPK1	S79	E81D	81	Missense	proximal	2	no	9.400	9.451	EPSD	TCGA;ICGC;COSMIC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q9H9S0	NANOG	P28482	MAPK1	S79	A85T	85	Missense	distal	6	no	9.400	9.486	EPSD	TCGA;ICGC;COSMIC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q9H9S0	NANOG	P28482	MAPK1	S258	Q255K	255	Missense	distal	-3	no	17.279	17.318	EPSD	TCGA;ICGC;COSMIC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q9H9S0	NANOG	P28482	MAPK1	S258	Q255E	255	Missense	distal	-3	no	17.279	17.396	EPSD	TCGA;ICGC;COSMIC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q9H9S0	NANOG	P28482	MAPK1	S258	E264D	264	Missense	distal	6	no	17.279	17.200	EPSD	TCGA;ICGC;COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q9H9S0	NANOG	P28482	MAPK1	T286	M290L	290	Missense	distal	4	no	14.092	14.170	EPSD	TCGA;ICGC;COSMIC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q9H9S0	NANOG	P28482	MAPK1	T289	M290L	290	Missense	proximal	1	no	3.479	9.373	EPSD	TCGA;ICGC;COSMIC	8.102	Gain
CMGC_MAPK_ERK1_MAPK1_ST	Q8IW41	MAPKAPK5	P28482	MAPK1	T182	T182P	182	Missense	central	0	yes	12.230	0.000	PhosphoSitePlus	TCGA;ICGC;COSMIC	8.102	Loss
CMGC_MAPK_ERK1_MAPK1_ST	Q8IW41	MAPKAPK5	P28482	MAPK1	T182	G178S	178	Missense	distal	-4	no	12.230	12.496	PhosphoSitePlus	TCGA;ICGC;COSMIC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q8IW41	MAPKAPK5	P28482	MAPK1	T186	T182P	182	Missense	distal	-4	no	15.853	16.167	EPSD	TCGA;ICGC;COSMIC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q8IW41	MAPKAPK5	P28482	MAPK1	S212	T214M	214	Missense	proximal	2	no	14.838	14.697	EPSD	TCGA;ICGC;COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q8IW41	MAPKAPK5	P28482	MAPK1	T214	T214M	214	Missense	central	0	yes	14.150	0.000	EPSD	TCGA;ICGC;COSMIC	8.102	Loss
CMGC_MAPK_ERK1_MAPK1_ST	Q8IW41	MAPKAPK5	P28482	MAPK1	T217	T214M	214	Missense	distal	-3	no	11.667	11.438	EPSD	TCGA;ICGC;COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q8IW41	MAPKAPK5	P28482	MAPK1	S469	E464D	464	Missense	distal	-5	no	8.799	8.844	EPSD	TCGA;COSMIC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P61978	HNRNPK	P28482	MAPK1	T13	E7K	7	Missense	distal	-6	no	9.240	9.214	EPSD	TCGA	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P61978	HNRNPK	P28482	MAPK1	T13	F10S	10	Missense	distal	-3	no	9.240	9.473	EPSD	TCGA;ICGC;COSMIC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P61978	HNRNPK	P28482	MAPK1	T13	T15P	15	Missense	proximal	2	no	9.240	9.291	EPSD	TCGA;ICGC;COSMIC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P61978	HNRNPK	P28482	MAPK1	T13	G20D	20	Missense	distal	7	no	9.240	9.167	EPSD	TCGA;ICGC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P61978	HNRNPK	P28482	MAPK1	S116	P117L	117	Missense	proximal	1	no	16.136	7.326	EPSD	TCGA;ICGC	8.102	Loss
CMGC_MAPK_ERK1_MAPK1_ST	P61978	HNRNPK	P28482	MAPK1	S188	T189A	189	Missense	proximal	1	no	8.030	8.898	EPSD	TCGA;ICGC;COSMIC	8.102	Gain
CMGC_MAPK_ERK1_MAPK1_ST	P61978	HNRNPK	P28482	MAPK1	S188	L194V	194	Missense	distal	6	no	8.030	8.222	EPSD	TCGA;ICGC;COSMIC	8.102	Gain
CMGC_MAPK_ERK1_MAPK1_ST	P61978	HNRNPK	P28482	MAPK1	S216	R221H	221	Missense	distal	5	no	12.959	12.782	EPSD	TCGA;ICGC;COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P61978	HNRNPK	P28482	MAPK1	S284	M283V	283	Missense	proximal	-1	no	14.740	14.764	PhosphoSitePlus	TCGA;ICGC;COSMIC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P61978	HNRNPK	P28482	MAPK1	S353	S355L	355	Missense	proximal	2	no	14.905	14.785	EPSD	TCGA;ICGC;COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P61978	HNRNPK	P28482	MAPK1	S353	E356D	356	Missense	distal	3	no	14.905	15.001	EPSD	TCGA;ICGC;COSMIC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P61978	HNRNPK	P28482	MAPK1	S353	E356A	356	Missense	distal	3	no	14.905	14.992	EPSD	TCGA;ICGC;COSMIC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P61978	HNRNPK	P28482	MAPK1	S379	A374S	374	Missense	distal	-5	no	10.565	10.514	EPSD	TCGA;ICGC;COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P61978	HNRNPK	P28482	MAPK1	S379	D382N	382	Missense	distal	3	no	10.565	10.469	EPSD	TCGA;ICGC;COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P61978	HNRNPK	P28482	MAPK1	S379	L383I	383	Missense	distal	4	no	10.565	10.508	EPSD	TCGA;ICGC;COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P61978	HNRNPK	P28482	MAPK1	S379	R377C	377	Missense	proximal	-2	no	10.565	8.617	EPSD	TCGA;ICGC;COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P29966	MARCKS	P28482	MAPK1	S27	P28L	28	Missense	proximal	1	no	15.041	6.232	EPSD	TCGA;ICGC;COSMIC	8.102	Loss
CMGC_MAPK_ERK1_MAPK1_ST	P29966	MARCKS	P28482	MAPK1	S27	S29F	29	Missense	proximal	2	no	15.041	14.910	EPSD	TCGA;ICGC;COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	O43524	FOXO3	P28482	MAPK1	S294	S299I	299	Missense	distal	5	no	15.577	15.260	PhosphoSitePlus;EPSD	TCGA;ICGC;COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	O43524	FOXO3	P28482	MAPK1	S294	R298C	298	Missense	distal	4	no	15.577	15.318	PhosphoSitePlus;EPSD	TCGA;ICGC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	O43524	FOXO3	P28482	MAPK1	S294	G293D	293	Missense	proximal	-1	no	15.577	15.576	PhosphoSitePlus;EPSD	TCGA;ICGC;COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	O43524	FOXO3	P28482	MAPK1	S325	R323L	323	Missense	proximal	-2	no	14.621	14.523	EPSD	TCGA;ICGC;COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	O43524	FOXO3	P28482	MAPK1	S325	M328I	328	Missense	distal	3	no	14.621	14.664	EPSD	TCGA;ICGC;COSMIC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	O43524	FOXO3	P28482	MAPK1	S344	A341V	341	Missense	distal	-3	no	18.067	18.127	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	O43524	FOXO3	P28482	MAPK1	S344	D340G	340	Missense	distal	-4	no	18.067	17.731	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	O43524	FOXO3	P28482	MAPK1	S355	C362F	362	Missense	distal	7	no	14.583	14.271	EPSD	TCGA;ICGC;COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	O43524	FOXO3	P28482	MAPK1	S402	P397S	397	Missense	distal	-5	no	13.773	13.847	EPSD	TCGA;ICGC;COSMIC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	O43524	FOXO3	P28482	MAPK1	S402	P397L	397	Missense	distal	-5	no	13.773	13.922	EPSD	TCGA;ICGC;COSMIC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	O43524	FOXO3	P28482	MAPK1	S402	S402L	402	Missense	central	0	yes	13.773	0.000	EPSD	TCGA;ICGC;COSMIC	8.102	Loss
CMGC_MAPK_ERK1_MAPK1_ST	O43524	FOXO3	P28482	MAPK1	S425	L423M	423	Missense	proximal	-2	no	14.483	12.386	EPSD;PhosphoSitePlus	TCGA;ICGC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	O43524	FOXO3	P28482	MAPK1	S425	S425F	425	Missense	central	0	yes	14.483	0.000	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	8.102	Loss
CMGC_MAPK_ERK1_MAPK1_ST	O43524	FOXO3	P28482	MAPK1	S446	Q449H	449	Missense	distal	3	no	14.355	14.376	EPSD	TCGA;ICGC;COSMIC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	O43524	FOXO3	P28482	MAPK1	S574	M580I	580	Missense	distal	6	no	13.629	13.395	EPSD	TCGA;ICGC;COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	O43524	FOXO3	P28482	MAPK1	S667	A665S	665	Missense	proximal	-2	no	10.107	10.419	EPSD	TCGA;ICGC;COSMIC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	O43524	FOXO3	P28482	MAPK1	S667	S669R	669	Missense	proximal	2	no	10.107	10.248	EPSD	TCGA;ICGC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P24941	CDK2	P28482	MAPK1	T14	K20E	20	Missense	distal	6	no	8.636	8.612	EPSD	TCGA;ICGC;COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P24941	CDK2	P28482	MAPK1	T14	G13D	13	Missense	proximal	-1	no	8.636	8.635	EPSD	TCGA;ICGC;COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P24941	CDK2	P28482	MAPK1	T221	D223Y	223	Missense	proximal	2	no	15.635	15.455	EPSD	TCGA;GDSC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q05209	PTPN12	P28482	MAPK1	S39	T44A	44	Missense	distal	5	no	9.162	9.076	EPSD	TCGA;ICGC;COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q05209	PTPN12	P28482	MAPK1	S39	K46M	46	Missense	distal	7	no	9.162	9.573	EPSD	TCGA;COSMIC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q05209	PTPN12	P28482	MAPK1	S39	R34W	34	Missense	distal	-5	no	9.162	9.438	EPSD	TCGA;COSMIC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q05209	PTPN12	P28482	MAPK1	T81	R74Q	74	Missense	distal	-7	no	13.888	13.896	EPSD	TCGA;ICGC;COSMIC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q05209	PTPN12	P28482	MAPK1	T81	D85N	85	Missense	distal	4	no	13.888	13.948	EPSD	TCGA;ICGC;COSMIC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q05209	PTPN12	P28482	MAPK1	S332	D331N	331	Missense	proximal	-1	no	13.654	13.715	EPSD	TCGA;COSMIC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q05209	PTPN12	P28482	MAPK1	T367	H360Y	360	Missense	distal	-7	no	13.750	13.730	EPSD	TCGA;COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q05209	PTPN12	P28482	MAPK1	S449	L443F	443	Missense	distal	-6	no	8.326	8.308	EPSD	TCGA;COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q05209	PTPN12	P28482	MAPK1	S449	G452V	452	Missense	distal	3	no	8.326	8.300	EPSD	TCGA	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q05209	PTPN12	P28482	MAPK1	S468	K474T	474	Missense	distal	6	no	14.904	14.637	EPSD	TCGA	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q05209	PTPN12	P28482	MAPK1	T509	N504D	504	Missense	distal	-5	no	12.461	12.505	EPSD	TCGA;COSMIC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q05209	PTPN12	P28482	MAPK1	T519	R525C	525	Missense	distal	6	no	12.568	11.808	EPSD	TCGA;COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q05209	PTPN12	P28482	MAPK1	T569	Q575K	575	Missense	distal	6	no	11.581	11.926	EPSD	TCGA;COSMIC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q05209	PTPN12	P28482	MAPK1	S571	Q575K	575	Missense	distal	4	no	13.707	13.792	PhosphoSitePlus	TCGA;COSMIC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q05209	PTPN12	P28482	MAPK1	T578	Q575K	575	Missense	distal	-3	no	13.878	13.917	EPSD	TCGA;COSMIC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q05209	PTPN12	P28482	MAPK1	T578	D585N	585	Missense	distal	7	no	13.878	13.865	EPSD	TCGA;COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q05209	PTPN12	P28482	MAPK1	S588	D585N	585	Missense	distal	-3	no	14.283	14.250	EPSD	TCGA;COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q05209	PTPN12	P28482	MAPK1	T593	T598I	598	Missense	distal	5	no	13.862	13.619	EPSD	TCGA;COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q05209	PTPN12	P28482	MAPK1	S596	T598I	598	Missense	proximal	2	no	9.774	9.653	EPSD	TCGA;COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q05209	PTPN12	P28482	MAPK1	S673	P678L	678	Missense	distal	5	no	11.964	11.751	EPSD	TCGA;COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q05209	PTPN12	P28482	MAPK1	S673	R680I	680	Missense	distal	7	no	11.964	12.509	EPSD	TCGA;COSMIC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q05209	PTPN12	P28482	MAPK1	T681	V686L	686	Missense	distal	5	no	12.353	12.264	EPSD	TCGA	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q05209	PTPN12	P28482	MAPK1	T681	P678L	678	Missense	distal	-3	no	12.353	11.969	EPSD	TCGA;COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q05209	PTPN12	P28482	MAPK1	T681	E683A	683	Missense	proximal	2	no	12.353	12.291	EPSD	TCGA;COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q05209	PTPN12	P28482	MAPK1	T681	E683G	683	Missense	proximal	2	no	12.353	12.439	EPSD	TCGA	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q05209	PTPN12	P28482	MAPK1	T681	R680I	680	Missense	proximal	-1	no	12.353	12.306	EPSD	TCGA;COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q05209	PTPN12	P28482	MAPK1	S684	V686L	686	Missense	proximal	2	no	10.959	10.865	EPSD	TCGA	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q05209	PTPN12	P28482	MAPK1	S684	P678L	678	Missense	distal	-6	no	10.959	10.867	EPSD	TCGA;COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q05209	PTPN12	P28482	MAPK1	S684	E683A	683	Missense	proximal	-1	no	10.959	10.937	EPSD	TCGA;COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q05209	PTPN12	P28482	MAPK1	S684	E683G	683	Missense	proximal	-1	no	10.959	10.920	EPSD	TCGA	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q05209	PTPN12	P28482	MAPK1	S684	R680I	680	Missense	distal	-4	no	10.959	10.378	EPSD	TCGA;COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q05209	PTPN12	P28482	MAPK1	T693	V686L	686	Missense	distal	-7	no	12.171	12.178	EPSD	TCGA	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q05209	PTPN12	P28482	MAPK1	T693	S700T	700	Missense	distal	7	no	12.171	12.324	EPSD	TCGA;COSMIC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q07820	MCL1	P28482	MAPK1	T163	S162W	162	Missense	proximal	-1	no	17.184	17.107	PhosphoSitePlus	TCGA;ICGC;COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P68400	CSNK2A1	P28482	MAPK1	T13	A9D	9	Missense	distal	-4	no	8.190	8.468	EPSD	TCGA;ICGC;COSMIC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P68400	CSNK2A1	P28482	MAPK1	T17	E22Q	22	Missense	distal	5	no	9.899	9.805	EPSD	TCGA;ICGC;COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P68400	CSNK2A1	P28482	MAPK1	T344	S347G	347	Missense	distal	3	no	15.195	15.209	EPSD	TCGA;ICGC;COSMIC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P68400	CSNK2A1	P28482	MAPK1	T344	G341W	341	Missense	distal	-3	no	15.195	14.665	EPSD	TCGA;ICGC;COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q9UKX7	NUP50	P28482	MAPK1	S221	P222A	222	Missense	proximal	1	no	14.761	7.130	EPSD;PhosphoSitePlus	TCGA;COSMIC	8.102	Loss
CMGC_MAPK_ERK1_MAPK1_ST	Q9UKX7	NUP50	P28482	MAPK1	S221	E218V	218	Missense	distal	-3	no	14.761	14.633	EPSD;PhosphoSitePlus	TCGA;COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q9UKX7	NUP50	P28482	MAPK1	S270	K275R	275	Missense	distal	5	no	8.071	8.206	EPSD	TCGA;COSMIC	8.102	Gain
CMGC_MAPK_ERK1_MAPK1_ST	Q9UKX7	NUP50	P28482	MAPK1	S314	S314A	314	Missense	central	0	yes	8.204	0.000	EPSD	TCGA;COSMIC	8.102	Loss
CMGC_MAPK_ERK1_MAPK1_ST	Q9UKX7	NUP50	P28482	MAPK1	S315	S314A	314	Missense	proximal	-1	no	15.287	15.293	PhosphoSitePlus;EPSD	TCGA;COSMIC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q08493	PDE4C	P28482	MAPK1	S100	Q98E	98	Missense	proximal	-2	no	13.736	14.350	EPSD	TCGA;ICGC;COSMIC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q08493	PDE4C	P28482	MAPK1	S100	Q98K	98	Missense	proximal	-2	no	13.736	14.310	EPSD	TCGA;ICGC;COSMIC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q08493	PDE4C	P28482	MAPK1	S100	S100N	100	Missense	central	0	yes	13.736	0.000	EPSD	TCGA;ICGC;COSMIC	8.102	Loss
CMGC_MAPK_ERK1_MAPK1_ST	Q08493	PDE4C	P28482	MAPK1	S100	I106N	106	Missense	distal	6	no	13.736	14.307	EPSD	TCGA;ICGC;COSMIC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q08493	PDE4C	P28482	MAPK1	S100	P97S	97	Missense	distal	-3	no	13.736	13.560	EPSD	TCGA;ICGC;COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q08493	PDE4C	P28482	MAPK1	S114	P112L	112	Missense	proximal	-2	no	8.476	6.559	EPSD	TCGA;ICGC;COSMIC;GDSC;CCLE	8.102	Loss
CMGC_MAPK_ERK1_MAPK1_ST	Q08493	PDE4C	P28482	MAPK1	S114	P110S	110	Missense	distal	-4	no	8.476	8.393	EPSD	TCGA;COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q08493	PDE4C	P28482	MAPK1	S131	Y128H	128	Missense	distal	-3	no	14.514	14.610	EPSD	TCGA;ICGC;COSMIC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q08493	PDE4C	P28482	MAPK1	S131	K133N	133	Missense	proximal	2	no	14.514	14.505	EPSD	TCGA;ICGC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q08493	PDE4C	P28482	MAPK1	S131	R137W	137	Missense	distal	6	no	14.514	13.591	EPSD	TCGA;ICGC;COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q08493	PDE4C	P28482	MAPK1	S131	D127N	127	Missense	distal	-4	no	14.514	14.486	EPSD	TCGA;ICGC;COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q08493	PDE4C	P28482	MAPK1	S641	R640Q	640	Missense	proximal	-1	no	17.959	17.937	EPSD	TCGA;COSMIC;GDSC;CCLE	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q08493	PDE4C	P28482	MAPK1	S641	P642L	642	Missense	proximal	1	no	17.959	9.149	EPSD	TCGA;COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q96LC9	BMF	P28482	MAPK1	S74	L73I	73	Missense	proximal	-1	no	15.634	15.628	PhosphoSitePlus;EPSD	TCGA;ICGC;COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q96LC9	BMF	P28482	MAPK1	S77	L73I	73	Missense	distal	-4	no	18.767	18.400	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q96LC9	BMF	P28482	MAPK1	S109	Y102S	102	Missense	distal	-7	no	9.393	9.424	EPSD	TCGA;ICGC;COSMIC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q96LC9	BMF	P28482	MAPK1	S109	P105H	105	Missense	distal	-4	no	9.393	9.151	EPSD	TCGA;ICGC;COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q15746	MYLK	P28482	MAPK1	S16	D20N	20	Missense	distal	4	no	8.118	8.177	EPSD	TCGA;ICGC;COSMIC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q15746	MYLK	P28482	MAPK1	S299	A292T	292	Missense	distal	-7	no	12.013	11.998	EPSD	TCGA;ICGC;COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q15746	MYLK	P28482	MAPK1	S299	K295N	295	Missense	distal	-4	no	12.013	11.981	EPSD	TCGA;ICGC;COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q15746	MYLK	P28482	MAPK1	S328	T331M	331	Missense	distal	3	no	14.314	14.337	EPSD	TCGA;ICGC;COSMIC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q15746	MYLK	P28482	MAPK1	T335	T331M	331	Missense	distal	-4	no	14.658	14.505	EPSD	TCGA;ICGC;COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q15746	MYLK	P28482	MAPK1	T335	T341N	341	Missense	distal	6	no	14.658	14.772	EPSD	TCGA;ICGC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q15746	MYLK	P28482	MAPK1	S365	R371K	371	Missense	distal	6	no	15.138	15.302	EPSD	TCGA;ICGC;COSMIC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q15746	MYLK	P28482	MAPK1	S515	S518G	518	Missense	distal	3	no	9.945	9.960	EPSD	TCGA;ICGC;COSMIC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q15746	MYLK	P28482	MAPK1	S515	S517F	517	Missense	proximal	2	no	9.945	9.813	EPSD	TCGA;ICGC;COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q15746	MYLK	P28482	MAPK1	S947	D952N	952	Missense	distal	5	no	14.753	14.655	EPSD	TCGA;ICGC;COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q15746	MYLK	P28482	MAPK1	S947	E940Q	940	Missense	distal	-7	no	14.753	14.751	EPSD	TCGA;ICGC;COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q15746	MYLK	P28482	MAPK1	S947	D952A	952	Missense	distal	5	no	14.753	14.568	EPSD	TCGA;ICGC;COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q15746	MYLK	P28482	MAPK1	S947	E942K	942	Missense	distal	-5	no	14.753	14.731	EPSD	TCGA;ICGC;COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q15746	MYLK	P28482	MAPK1	S947	R954C	954	Missense	distal	7	no	14.753	15.409	EPSD	TCGA;ICGC;COSMIC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q15746	MYLK	P28482	MAPK1	S947	E940D	940	Missense	distal	-7	no	14.753	14.745	EPSD	TCGA;ICGC;COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q15746	MYLK	P28482	MAPK1	T978	P979L	979	Missense	proximal	1	no	16.073	7.263	EPSD	TCGA;ICGC;COSMIC	8.102	Loss
CMGC_MAPK_ERK1_MAPK1_ST	Q15746	MYLK	P28482	MAPK1	T978	R982C	982	Missense	distal	4	no	16.073	15.814	EPSD	TCGA;ICGC;COSMIC;GDSC;CCLE	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q15746	MYLK	P28482	MAPK1	T1230	M1236I	1236	Missense	distal	6	no	14.393	14.159	EPSD	TCGA	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q15746	MYLK	P28482	MAPK1	T1230	P1237S	1237	Missense	distal	7	no	14.393	14.404	EPSD	TCGA;ICGC;COSMIC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q15746	MYLK	P28482	MAPK1	T1230	A1235V	1235	Missense	distal	5	no	14.393	14.410	EPSD	TCGA;ICGC;COSMIC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q15746	MYLK	P28482	MAPK1	T1230	M1236L	1236	Missense	distal	6	no	14.393	14.420	EPSD	TCGA;ICGC;COSMIC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q15746	MYLK	P28482	MAPK1	S1659	D1664G	1664	Missense	distal	5	no	12.634	12.589	EPSD	TCGA;ICGC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q15746	MYLK	P28482	MAPK1	S1776	P1780S	1780	Missense	distal	4	no	12.880	12.869	EPSD	TCGA;COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q15746	MYLK	P28482	MAPK1	S1779	P1780S	1780	Missense	proximal	1	no	16.167	6.772	PhosphoSitePlus	TCGA;COSMIC	8.102	Loss
CMGC_MAPK_ERK1_MAPK1_ST	O75581	LRP6	P28482	MAPK1	S646	I645L	645	Missense	proximal	-1	no	8.517	8.523	EPSD	TCGA;ICGC;COSMIC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	O75581	LRP6	P28482	MAPK1	S646	R644Q	644	Missense	proximal	-2	no	8.517	7.342	EPSD	TCGA;ICGC;COSMIC	8.102	Loss
CMGC_MAPK_ERK1_MAPK1_ST	O75581	LRP6	P28482	MAPK1	S646	I642S	642	Missense	distal	-4	no	8.517	9.104	EPSD	TCGA	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	O75581	LRP6	P28482	MAPK1	S1430	S1431Y	1431	Missense	proximal	1	no	6.017	8.403	EPSD	TCGA;COSMIC	8.102	Gain
CMGC_MAPK_ERK1_MAPK1_ST	O75581	LRP6	P28482	MAPK1	S1430	S1431F	1431	Missense	proximal	1	no	6.017	8.842	EPSD	TCGA;COSMIC	8.102	Gain
CMGC_MAPK_ERK1_MAPK1_ST	O75581	LRP6	P28482	MAPK1	S1431	S1435T	1435	Missense	distal	4	no	8.341	8.228	EPSD	TCGA	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	O75581	LRP6	P28482	MAPK1	S1431	S1431Y	1431	Missense	central	0	yes	8.341	0.000	EPSD	TCGA;COSMIC	8.102	Loss
CMGC_MAPK_ERK1_MAPK1_ST	O75581	LRP6	P28482	MAPK1	S1431	S1431F	1431	Missense	central	0	yes	8.341	0.000	EPSD	TCGA;COSMIC	8.102	Loss
CMGC_MAPK_ERK1_MAPK1_ST	O75581	LRP6	P28482	MAPK1	S1431	L1432V	1432	Missense	proximal	1	no	8.341	7.610	EPSD	TCGA;COSMIC	8.102	Loss
CMGC_MAPK_ERK1_MAPK1_ST	O75581	LRP6	P28482	MAPK1	S1431	S1433A	1433	Missense	proximal	2	no	8.341	8.239	EPSD	TCGA	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	O75581	LRP6	P28482	MAPK1	S1508	G1503E	1503	Missense	distal	-5	no	14.168	14.125	EPSD	TCGA;COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	O75581	LRP6	P28482	MAPK1	S1508	S1505Y	1505	Missense	distal	-3	no	14.168	13.898	EPSD	TCGA	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	O75581	LRP6	P28482	MAPK1	S1516	R1523W	1523	Missense	distal	7	no	7.746	8.717	EPSD	TCGA;COSMIC	8.102	Gain
CMGC_MAPK_ERK1_MAPK1_ST	O75581	LRP6	P28482	MAPK1	S1521	R1523W	1523	Missense	proximal	2	no	9.568	9.199	EPSD	TCGA;COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	O75581	LRP6	P28482	MAPK1	S1521	H1524Q	1524	Missense	distal	3	no	9.568	9.547	EPSD	TCGA;COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	O75581	LRP6	P28482	MAPK1	S1521	H1524Y	1524	Missense	distal	3	no	9.568	9.606	EPSD	TCGA	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	O75581	LRP6	P28482	MAPK1	S1521	P1519S	1519	Missense	proximal	-2	no	9.568	6.733	EPSD	TCGA;COSMIC	8.102	Loss
CMGC_MAPK_ERK1_MAPK1_ST	O75581	LRP6	P28482	MAPK1	T1530	R1523W	1523	Missense	distal	-7	no	16.491	16.441	EPSD	TCGA;COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	O75581	LRP6	P28482	MAPK1	T1530	H1524Q	1524	Missense	distal	-6	no	16.491	16.551	EPSD	TCGA;COSMIC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	O75581	LRP6	P28482	MAPK1	T1530	H1524Y	1524	Missense	distal	-6	no	16.491	16.426	EPSD	TCGA	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	O75581	LRP6	P28482	MAPK1	T1572	S1579P	1579	Missense	distal	7	no	16.928	16.917	EPSD;PhosphoSitePlus	TCGA;COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	O75581	LRP6	P28482	MAPK1	T1572	R1574Q	1574	Missense	proximal	2	no	16.928	16.637	EPSD;PhosphoSitePlus	TCGA;COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	O75581	LRP6	P28482	MAPK1	S1575	S1579P	1579	Missense	distal	4	no	9.163	9.174	EPSD	TCGA;COSMIC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	O75581	LRP6	P28482	MAPK1	S1575	R1574Q	1574	Missense	proximal	-1	no	9.163	9.142	EPSD	TCGA;COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	O75581	LRP6	P28482	MAPK1	S1590	S1596G	1596	Missense	distal	6	no	18.421	18.343	EPSD	TCGA;COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	O75581	LRP6	P28482	MAPK1	T1593	H1599D	1599	Missense	distal	6	no	7.884	8.144	EPSD	TCGA;COSMIC	8.102	Gain
CMGC_MAPK_ERK1_MAPK1_ST	O75581	LRP6	P28482	MAPK1	S1607	P1604T	1604	Missense	distal	-3	no	18.829	18.619	EPSD	TCGA;COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q02447	SP3	P28482	MAPK1	S73	I69M	69	Missense	distal	-4	no	15.704	15.909	PhosphoSitePlus	TCGA;COSMIC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q02447	SP3	P28482	MAPK1	S317	R315W	315	Missense	proximal	-2	no	14.614	13.691	EPSD	TCGA;COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q02447	SP3	P28482	MAPK1	S378	Q384R	384	Missense	distal	6	no	8.642	8.822	EPSD	TCGA	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q02447	SP3	P28482	MAPK1	S544	N541D	541	Missense	distal	-3	no	12.285	12.317	EPSD	TCGA;COSMIC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q8IX03	WWC1	P28482	MAPK1	S441	R446Q	446	Missense	distal	5	no	9.221	9.050	EPSD	TCGA;ICGC;COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q8IX03	WWC1	P28482	MAPK1	T527	S525F	525	Missense	proximal	-2	no	15.324	15.518	EPSD	TCGA;ICGC;COSMIC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q8IX03	WWC1	P28482	MAPK1	T527	P528S	528	Missense	proximal	1	no	15.324	5.930	EPSD	TCGA;ICGC;COSMIC	8.102	Loss
CMGC_MAPK_ERK1_MAPK1_ST	Q8IX03	WWC1	P28482	MAPK1	T527	S523F	523	Missense	distal	-4	no	15.324	15.063	EPSD	TCGA;ICGC;COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q8IX03	WWC1	P28482	MAPK1	T527	S533F	533	Missense	distal	6	no	15.324	14.884	EPSD	TCGA;ICGC;COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q8IX03	WWC1	P28482	MAPK1	T527	M531I	531	Missense	distal	4	no	15.324	15.346	EPSD	TCGA;ICGC;COSMIC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q8IX03	WWC1	P28482	MAPK1	T532	S533F	533	Missense	proximal	1	no	5.713	8.539	EPSD	TCGA;ICGC;COSMIC	8.102	Gain
CMGC_MAPK_ERK1_MAPK1_ST	Q8IX03	WWC1	P28482	MAPK1	S535	R537C	537	Missense	proximal	2	no	13.626	13.253	EPSD	TCGA;ICGC;COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q8IX03	WWC1	P28482	MAPK1	S535	P528S	528	Missense	distal	-7	no	13.626	13.622	EPSD	TCGA;ICGC;COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q8IX03	WWC1	P28482	MAPK1	S535	L540F	540	Missense	distal	5	no	13.626	13.660	EPSD	TCGA;ICGC;COSMIC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q8IX03	WWC1	P28482	MAPK1	S535	P536S	536	Missense	proximal	1	no	13.626	4.232	EPSD	TCGA;ICGC;COSMIC	8.102	Loss
CMGC_MAPK_ERK1_MAPK1_ST	Q8IX03	WWC1	P28482	MAPK1	S535	S533F	533	Missense	proximal	-2	no	13.626	13.820	EPSD	TCGA;ICGC;COSMIC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q8IX03	WWC1	P28482	MAPK1	S535	M531I	531	Missense	distal	-4	no	13.626	13.421	EPSD	TCGA;ICGC;COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q8IX03	WWC1	P28482	MAPK1	S539	L540F	540	Missense	proximal	1	no	6.066	8.306	EPSD	TCGA;ICGC;COSMIC	8.102	Gain
CMGC_MAPK_ERK1_MAPK1_ST	Q8IX03	WWC1	P28482	MAPK1	S542	P549L	549	Missense	distal	7	no	15.040	15.339	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q8IX03	WWC1	P28482	MAPK1	S542	R537C	537	Missense	distal	-5	no	15.040	15.270	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q8IX03	WWC1	P28482	MAPK1	S542	L540F	540	Missense	proximal	-2	no	15.040	14.316	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q8IX03	WWC1	P28482	MAPK1	S542	S548F	548	Missense	distal	6	no	15.040	14.599	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q8IX03	WWC1	P28482	MAPK1	S542	P536S	536	Missense	distal	-6	no	15.040	15.014	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q8IX03	WWC1	P28482	MAPK1	S548	P549L	549	Missense	proximal	1	no	17.430	8.621	PhosphoSitePlus;EPSD	TCGA;ICGC;COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q8IX03	WWC1	P28482	MAPK1	S548	M551I	551	Missense	distal	3	no	17.430	17.473	PhosphoSitePlus;EPSD	TCGA;ICGC;COSMIC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q8IX03	WWC1	P28482	MAPK1	S548	S548F	548	Missense	central	0	yes	17.430	0.000	PhosphoSitePlus;EPSD	TCGA;ICGC;COSMIC	8.102	Loss
CMGC_MAPK_ERK1_MAPK1_ST	Q8IX03	WWC1	P28482	MAPK1	S876	A875D	875	Missense	proximal	-1	no	13.752	13.733	EPSD	TCGA;ICGC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q8IX03	WWC1	P28482	MAPK1	T895	P898S	898	Missense	distal	3	no	12.565	12.634	EPSD	TCGA;ICGC;COSMIC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q8IX03	WWC1	P28482	MAPK1	T895	S899P	899	Missense	distal	4	no	12.565	12.576	EPSD	TCGA;ICGC;COSMIC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q8IX03	WWC1	P28482	MAPK1	S899	P898S	898	Missense	proximal	-1	no	14.356	14.313	EPSD	TCGA;ICGC;COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q8IX03	WWC1	P28482	MAPK1	S899	S899P	899	Missense	central	0	yes	14.356	0.000	EPSD	TCGA;ICGC;COSMIC	8.102	Loss
CMGC_MAPK_ERK1_MAPK1_ST	Q8IX03	WWC1	P28482	MAPK1	T912	S914F	914	Missense	proximal	2	no	12.850	12.718	EPSD	TCGA;ICGC;COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q8IX03	WWC1	P28482	MAPK1	T912	P913L	913	Missense	proximal	1	no	12.850	4.040	EPSD	TCGA	8.102	Loss
CMGC_MAPK_ERK1_MAPK1_ST	Q8IX03	WWC1	P28482	MAPK1	S931	R926C	926	Missense	distal	-5	no	13.632	13.862	EPSD	TCGA;ICGC;COSMIC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q8IX03	WWC1	P28482	MAPK1	S931	Q937K	937	Missense	distal	6	no	13.632	13.977	EPSD	TCGA;ICGC;COSMIC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q8IX03	WWC1	P28482	MAPK1	S931	S931F	931	Missense	central	0	yes	13.632	0.000	EPSD	TCGA;ICGC;COSMIC	8.102	Loss
CMGC_MAPK_ERK1_MAPK1_ST	Q8IX03	WWC1	P28482	MAPK1	S931	F930S	930	Missense	proximal	-1	no	13.632	13.678	EPSD	TCGA;ICGC;COSMIC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q8IX03	WWC1	P28482	MAPK1	S936	Q937K	937	Missense	proximal	1	no	9.701	-0.324	EPSD	TCGA;ICGC;COSMIC	8.102	Loss
CMGC_MAPK_ERK1_MAPK1_ST	Q8IX03	WWC1	P28482	MAPK1	S936	V939L	939	Missense	distal	3	no	9.701	9.734	EPSD	TCGA;ICGC;COSMIC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q8IX03	WWC1	P28482	MAPK1	S936	S931F	931	Missense	distal	-5	no	9.701	9.790	EPSD	TCGA;ICGC;COSMIC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q8IX03	WWC1	P28482	MAPK1	S936	R941W	941	Missense	distal	5	no	9.701	9.173	EPSD	TCGA;ICGC;COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q8IX03	WWC1	P28482	MAPK1	S936	F930S	930	Missense	distal	-6	no	9.701	9.786	EPSD	TCGA;ICGC;COSMIC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P11362	FGFR1	P28482	MAPK1	T454	S461F	461	Missense	distal	7	no	12.097	12.444	EPSD	TCGA;COSMIC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P01106	MYC	P28482	MAPK1	T58	E54D	54	Missense	distal	-4	no	15.566	15.581	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC;GDSC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P01106	MYC	P28482	MAPK1	S161	S161L	161	Missense	central	0	yes	14.115	0.000	EPSD	TCGA;ICGC;COSMIC	8.102	Loss
CMGC_MAPK_ERK1_MAPK1_ST	P01106	MYC	P28482	MAPK1	S204	S207L	207	Missense	distal	3	no	12.836	12.856	EPSD	TCGA;ICGC;COSMIC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P01106	MYC	P28482	MAPK1	S344	K341R	341	Missense	distal	-3	no	13.324	13.562	EPSD	TCGA;ICGC;COSMIC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P01106	MYC	P28482	MAPK1	S347	K341R	341	Missense	distal	-6	no	9.418	9.441	EPSD	TCGA;ICGC;COSMIC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P14784	IL2RB	P28482	MAPK1	T282	F288L	288	Missense	distal	6	no	10.709	10.743	EPSD	TCGA;ICGC;COSMIC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P14784	IL2RB	P28482	MAPK1	S431	P438A	438	Missense	distal	7	no	13.075	13.267	EPSD	TCGA;ICGC;COSMIC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P14784	IL2RB	P28482	MAPK1	S431	S433R	433	Missense	proximal	2	no	13.075	13.216	EPSD	TCGA;ICGC;COSMIC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P14784	IL2RB	P28482	MAPK1	S458	R454K	454	Missense	distal	-4	no	8.389	8.468	EPSD	TCGA;ICGC;COSMIC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P14784	IL2RB	P28482	MAPK1	S458	E452K	452	Missense	distal	-6	no	8.389	8.363	EPSD	TCGA;ICGC;COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P14784	IL2RB	P28482	MAPK1	S458	R462K	462	Missense	distal	4	no	8.389	8.399	EPSD	TCGA;ICGC;COSMIC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P14784	IL2RB	P28482	MAPK1	S458	P457S	457	Missense	proximal	-1	no	8.389	8.346	EPSD	TCGA;ICGC;COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P14784	IL2RB	P28482	MAPK1	T476	P474S	474	Missense	proximal	-2	no	15.778	12.944	PhosphoSitePlus	TCGA;ICGC;COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P14784	IL2RB	P28482	MAPK1	T476	P480S	480	Missense	distal	4	no	15.778	15.767	PhosphoSitePlus	TCGA;ICGC;COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P14784	IL2RB	P28482	MAPK1	T533	R528C	528	Missense	distal	-5	no	8.864	9.094	EPSD	TCGA;ICGC;COSMIC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P49841	GSK3B	P28482	MAPK1	S21	Q19R	19	Missense	proximal	-2	no	7.852	9.027	EPSD	TCGA	8.102	Gain
CMGC_MAPK_ERK1_MAPK1_ST	P49841	GSK3B	P28482	MAPK1	T43	D49N	49	Missense	distal	6	no	15.197	15.147	PhosphoSitePlus	TCGA;ICGC;COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P49841	GSK3B	P28482	MAPK1	S215	Y216C	216	Missense	proximal	1	no	8.103	1.664	EPSD	TCGA;ICGC;COSMIC	8.102	Loss
CMGC_MAPK_ERK1_MAPK1_ST	P49841	GSK3B	P28482	MAPK1	S215	S215L	215	Missense	central	0	yes	8.103	0.000	EPSD	TCGA;ICGC;COSMIC	8.102	Loss
CMGC_MAPK_ERK1_MAPK1_ST	P06239	LCK	P28482	MAPK1	S42	T35M	35	Missense	distal	-7	no	9.303	9.299	EPSD	TCGA;ICGC;COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P06239	LCK	P28482	MAPK1	S42	V44L	44	Missense	proximal	2	no	9.303	9.209	EPSD	TCGA;ICGC;COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P06239	LCK	P28482	MAPK1	S42	R39Q	39	Missense	distal	-3	no	9.303	9.026	EPSD	TCGA;ICGC;COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P06239	LCK	P28482	MAPK1	S42	R45W	45	Missense	distal	3	no	9.303	9.453	EPSD	TCGA;ICGC;COSMIC;GDSC;CCLE	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P06239	LCK	P28482	MAPK1	S59	E52K	52	Missense	distal	-7	no	17.671	17.664	PhosphoSitePlus	TCGA;ICGC;COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P06239	LCK	P28482	MAPK1	S59	P56L	56	Missense	distal	-3	no	17.671	17.287	PhosphoSitePlus	TCGA;ICGC;COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P06239	LCK	P28482	MAPK1	S156	E157K	157	Missense	proximal	1	no	8.235	-1.512	EPSD	TCGA;COSMIC	8.102	Loss
CMGC_MAPK_ERK1_MAPK1_ST	P06239	LCK	P28482	MAPK1	S194	F191L	191	Missense	distal	-3	no	15.100	15.125	EPSD	TCGA;COSMIC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P06239	LCK	P28482	MAPK1	S194	R196Q	196	Missense	proximal	2	no	15.100	14.809	EPSD	TCGA;COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P06239	LCK	P28482	MAPK1	T198	F191L	191	Missense	distal	-7	no	9.968	9.980	EPSD	TCGA;COSMIC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P06239	LCK	P28482	MAPK1	T198	L202M	202	Missense	distal	4	no	9.968	9.890	EPSD	TCGA;COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P06239	LCK	P28482	MAPK1	T198	P200S	200	Missense	proximal	2	no	9.968	9.940	EPSD	TCGA;COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P06239	LCK	P28482	MAPK1	T198	R196Q	196	Missense	proximal	-2	no	9.968	8.793	EPSD	TCGA;COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P06239	LCK	P28482	MAPK1	S281	Q277K	277	Missense	distal	-4	no	14.176	14.358	EPSD	TCGA;COSMIC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P06239	LCK	P28482	MAPK1	S281	S274N	274	Missense	distal	-7	no	14.176	14.179	EPSD	TCGA;COSMIC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P06239	LCK	P28482	MAPK1	S281	S281F	281	Missense	central	0	yes	14.176	0.000	EPSD	TCGA;COSMIC	8.102	Loss
CMGC_MAPK_ERK1_MAPK1_ST	P06239	LCK	P28482	MAPK1	S281	A284T	284	Missense	distal	3	no	14.176	14.160	EPSD	TCGA	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P06239	LCK	P28482	MAPK1	S373	V372M	372	Missense	proximal	-1	no	8.607	8.583	EPSD	TCGA;COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P06239	LCK	P28482	MAPK1	S373	T375I	375	Missense	proximal	2	no	8.607	8.487	EPSD	TCGA	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P06239	LCK	P28482	MAPK1	S373	R366Q	366	Missense	distal	-7	no	8.607	8.615	EPSD	TCGA;COSMIC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P06239	LCK	P28482	MAPK1	S492	R491H	491	Missense	proximal	-1	no	8.103	8.080	EPSD	TCGA;ICGC;COSMIC	8.102	Loss
CMGC_MAPK_ERK1_MAPK1_ST	P42702	LIFR	P28482	MAPK1	S534	A533D	533	Missense	proximal	-1	no	16.663	16.644	EPSD	TCGA;ICGC;COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P42702	LIFR	P28482	MAPK1	S534	E532K	532	Missense	proximal	-2	no	16.663	16.623	EPSD	TCGA;ICGC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P42702	LIFR	P28482	MAPK1	T541	S546R	546	Missense	distal	5	no	11.630	11.662	EPSD	TCGA;ICGC;COSMIC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P42702	LIFR	P28482	MAPK1	T541	W542C	542	Missense	proximal	1	no	11.630	5.558	EPSD	TCGA;ICGC	8.102	Loss
CMGC_MAPK_ERK1_MAPK1_ST	P42702	LIFR	P28482	MAPK1	T904	L911V	911	Missense	distal	7	no	15.958	15.952	EPSD	TCGA;ICGC;COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P42702	LIFR	P28482	MAPK1	T904	P902S	902	Missense	proximal	-2	no	15.958	13.124	EPSD	TCGA;ICGC;COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P42702	LIFR	P28482	MAPK1	T904	P902H	902	Missense	proximal	-2	no	15.958	13.203	EPSD	TCGA;ICGC;COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P42702	LIFR	P28482	MAPK1	S927	R932H	932	Missense	distal	5	no	14.180	14.003	EPSD	TCGA;ICGC;COSMIC;GDSC;CCLE	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P42702	LIFR	P28482	MAPK1	S1041	N1038T	1038	Missense	distal	-3	no	15.138	15.090	EPSD	TCGA;ICGC;COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P42702	LIFR	P28482	MAPK1	S1041	D1043N	1043	Missense	proximal	2	no	15.138	15.077	EPSD	TCGA;ICGC;COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P42702	LIFR	P28482	MAPK1	S1041	S1047F	1047	Missense	distal	6	no	15.138	14.697	EPSD	TCGA;ICGC;COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P42702	LIFR	P28482	MAPK1	S1041	P1045L	1045	Missense	distal	4	no	15.138	15.017	EPSD	TCGA;ICGC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P42702	LIFR	P28482	MAPK1	S1044	N1038T	1038	Missense	distal	-6	no	18.089	18.062	PhosphoSitePlus	TCGA;ICGC;COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P42702	LIFR	P28482	MAPK1	S1044	D1043N	1043	Missense	proximal	-1	no	18.089	18.150	PhosphoSitePlus	TCGA;ICGC;COSMIC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P42702	LIFR	P28482	MAPK1	S1044	N1051Y	1051	Missense	distal	7	no	18.089	18.624	PhosphoSitePlus	TCGA;ICGC;COSMIC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P42702	LIFR	P28482	MAPK1	S1044	S1047F	1047	Missense	distal	3	no	18.089	18.151	PhosphoSitePlus	TCGA;ICGC;COSMIC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P42702	LIFR	P28482	MAPK1	S1044	P1045L	1045	Missense	proximal	1	no	18.089	9.279	PhosphoSitePlus	TCGA;ICGC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P42702	LIFR	P28482	MAPK1	S1047	D1043N	1043	Missense	distal	-4	no	8.706	8.678	EPSD	TCGA;ICGC;COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P42702	LIFR	P28482	MAPK1	S1047	N1051Y	1051	Missense	distal	4	no	8.706	8.549	EPSD	TCGA;ICGC;COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P42702	LIFR	P28482	MAPK1	S1047	S1047F	1047	Missense	central	0	yes	8.706	0.000	EPSD	TCGA;ICGC;COSMIC	8.102	Loss
CMGC_MAPK_ERK1_MAPK1_ST	P42702	LIFR	P28482	MAPK1	S1047	I1054L	1054	Missense	distal	7	no	8.706	8.447	EPSD	TCGA;ICGC;COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P42702	LIFR	P28482	MAPK1	S1047	P1045L	1045	Missense	proximal	-2	no	8.706	6.789	EPSD	TCGA;ICGC	8.102	Loss
CMGC_MAPK_ERK1_MAPK1_ST	P42702	LIFR	P28482	MAPK1	S1050	N1051Y	1051	Missense	proximal	1	no	-3.861	8.853	EPSD	TCGA;ICGC;COSMIC	8.102	Gain
CMGC_MAPK_ERK1_MAPK1_ST	P42702	LIFR	P28482	MAPK1	S1056	S1062F	1062	Missense	distal	6	no	10.056	9.616	EPSD	TCGA;ICGC;COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P42702	LIFR	P28482	MAPK1	S1056	N1051Y	1051	Missense	distal	-5	no	10.056	10.236	EPSD	TCGA;ICGC;COSMIC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P42702	LIFR	P28482	MAPK1	S1056	G1058E	1058	Missense	proximal	2	no	10.056	9.970	EPSD	TCGA;ICGC;COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P42702	LIFR	P28482	MAPK1	S1056	I1054L	1054	Missense	proximal	-2	no	10.056	10.033	EPSD	TCGA;ICGC;COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P42702	LIFR	P28482	MAPK1	S1059	S1062F	1062	Missense	distal	3	no	13.739	13.801	EPSD	TCGA;ICGC;COSMIC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P42702	LIFR	P28482	MAPK1	S1059	R1066Q	1066	Missense	distal	7	no	13.739	13.854	EPSD	TCGA;ICGC;COSMIC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P42702	LIFR	P28482	MAPK1	S1059	G1058E	1058	Missense	proximal	-1	no	13.739	13.778	EPSD	TCGA;ICGC;COSMIC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P42702	LIFR	P28482	MAPK1	S1059	S1065F	1065	Missense	distal	6	no	13.739	13.298	EPSD	TCGA;ICGC;COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P42702	LIFR	P28482	MAPK1	S1059	I1054L	1054	Missense	distal	-5	no	13.739	13.679	EPSD	TCGA;ICGC;COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P42702	LIFR	P28482	MAPK1	S1062	S1062F	1062	Missense	central	0	yes	8.299	0.000	EPSD	TCGA;ICGC;COSMIC	8.102	Loss
CMGC_MAPK_ERK1_MAPK1_ST	P42702	LIFR	P28482	MAPK1	S1062	R1066Q	1066	Missense	distal	4	no	8.299	8.224	EPSD	TCGA;ICGC;COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P42702	LIFR	P28482	MAPK1	S1062	G1058E	1058	Missense	distal	-4	no	8.299	8.620	EPSD	TCGA;ICGC;COSMIC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P42702	LIFR	P28482	MAPK1	S1062	S1065F	1065	Missense	distal	3	no	8.299	8.361	EPSD	TCGA;ICGC;COSMIC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P42702	LIFR	P28482	MAPK1	S1077	G1082E	1082	Missense	distal	5	no	15.325	15.301	EPSD	TCGA;ICGC;COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P42702	LIFR	P28482	MAPK1	S1077	G1083E	1083	Missense	distal	6	no	15.325	15.436	EPSD	TCGA;ICGC;COSMIC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q14247	CTTN	P28482	MAPK1	S113	Q114P	114	Missense	proximal	1	no	5.595	14.089	EPSD	TCGA;ICGC;COSMIC	8.102	Gain
CMGC_MAPK_ERK1_MAPK1_ST	P62070	RRAS2	P28482	MAPK1	T190	D195Y	195	Missense	distal	5	no	8.911	8.597	EPSD	TCGA	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q00059	TFAM	P28482	MAPK1	S56	K51N	51	Missense	distal	-5	no	8.734	8.757	EPSD	TCGA;ICGC;COSMIC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q00059	TFAM	P28482	MAPK1	T122	S128F	128	Missense	distal	6	no	13.089	12.648	EPSD	TCGA;ICGC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q00059	TFAM	P28482	MAPK1	T122	L129F	129	Missense	distal	7	no	13.089	13.148	EPSD	TCGA;ICGC;COSMIC;GDSC;CCLE	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q00059	TFAM	P28482	MAPK1	S160	R159C	159	Missense	proximal	-1	no	8.338	8.236	EPSD	TCGA;ICGC;COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q00059	TFAM	P28482	MAPK1	S160	R159L	159	Missense	proximal	-1	no	8.338	8.298	EPSD	TCGA;ICGC;COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q00059	TFAM	P28482	MAPK1	S177	A173S	173	Missense	distal	-4	no	12.822	13.032	PhosphoSitePlus	TCGA;ICGC;COSMIC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q05682	CALD1	P28482	MAPK1	S153	E151V	151	Missense	proximal	-2	no	8.468	8.975	EPSD	TCGA;COSMIC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q05682	CALD1	P28482	MAPK1	S153	T146A	146	Missense	distal	-7	no	8.468	8.482	EPSD	TCGA;COSMIC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q05682	CALD1	P28482	MAPK1	S480	V478G	478	Missense	proximal	-2	no	8.366	7.045	EPSD	TCGA;COSMIC	8.102	Loss
CMGC_MAPK_ERK1_MAPK1_ST	Q05682	CALD1	P28482	MAPK1	S480	K485N	485	Missense	distal	5	no	8.366	8.397	EPSD	TCGA;COSMIC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q05682	CALD1	P28482	MAPK1	T638	S643Y	643	Missense	distal	5	no	12.242	11.954	EPSD	TCGA;COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q05682	CALD1	P28482	MAPK1	T638	S643F	643	Missense	distal	5	no	12.242	12.045	EPSD	TCGA;COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q05682	CALD1	P28482	MAPK1	T638	F634C	634	Missense	distal	-4	no	12.242	11.860	EPSD	TCGA;COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q05682	CALD1	P28482	MAPK1	S759	S765Y	765	Missense	distal	6	no	12.022	11.403	EPSD	TCGA	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P00558	PGK1	P28482	MAPK1	S203	F197I	197	Missense	distal	-6	no	14.700	14.683	PhosphoSitePlus	TCGA;ICGC;COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P00558	PGK1	P28482	MAPK1	S203	K199N	199	Missense	distal	-4	no	14.700	14.669	PhosphoSitePlus	TCGA;ICGC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P00558	PGK1	P28482	MAPK1	S399	L402P	402	Missense	distal	3	no	8.780	8.690	EPSD	TCGA	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P46527	CDKN1B	P28482	MAPK1	S10	S7C	7	Missense	distal	-3	no	14.720	14.193	PhosphoSitePlus;EPSD	TCGA;ICGC;COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P46527	CDKN1B	P28482	MAPK1	S10	G9W	9	Missense	proximal	-1	no	14.720	14.653	PhosphoSitePlus;EPSD	TCGA;ICGC;COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P11308	ERG	P28482	MAPK1	T32	E27Q	27	Missense	distal	-5	no	14.088	14.188	EPSD	TCGA;COSMIC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P11308	ERG	P28482	MAPK1	T32	P33S	33	Missense	proximal	1	no	14.088	4.693	EPSD	TCGA;COSMIC	8.102	Loss
CMGC_MAPK_ERK1_MAPK1_ST	P11308	ERG	P28482	MAPK1	S55	P59R	59	Missense	distal	4	no	15.048	15.014	EPSD	TCGA	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P11308	ERG	P28482	MAPK1	S55	V58I	58	Missense	distal	3	no	15.048	15.118	EPSD	TCGA;COSMIC;GDSC;CCLE	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P11308	ERG	P28482	MAPK1	S103	G108R	108	Missense	distal	5	no	16.533	16.584	PhosphoSitePlus;EPSD	TCGA;COSMIC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P11308	ERG	P28482	MAPK1	S103	V107I	107	Missense	distal	4	no	16.533	16.466	PhosphoSitePlus;EPSD	TCGA;COSMIC;GDSC;CCLE	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P11308	ERG	P28482	MAPK1	S222	R224W	224	Missense	proximal	2	no	13.432	13.064	EPSD;PhosphoSitePlus	TCGA;COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P11308	ERG	P28482	MAPK1	S222	Q220H	220	Missense	proximal	-2	no	13.432	13.671	EPSD;PhosphoSitePlus	TCGA;COSMIC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P11308	ERG	P28482	MAPK1	S222	S222F	222	Missense	central	0	yes	13.432	0.000	EPSD;PhosphoSitePlus	TCGA;COSMIC	8.102	Loss
CMGC_MAPK_ERK1_MAPK1_ST	P11308	ERG	P28482	MAPK1	S222	P223T	223	Missense	proximal	1	no	13.432	4.934	EPSD;PhosphoSitePlus	TCGA;COSMIC	8.102	Loss
CMGC_MAPK_ERK1_MAPK1_ST	P22736	NR4A1	P28482	MAPK1	S23	P28L	28	Missense	distal	5	no	8.780	8.567	EPSD	TCGA;COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P22736	NR4A1	P28482	MAPK1	T27	P28L	28	Missense	proximal	1	no	18.074	9.264	EPSD	TCGA;COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P22736	NR4A1	P28482	MAPK1	S237	G232V	232	Missense	distal	-5	no	18.051	18.079	EPSD	TCGA;ICGC;COSMIC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P27708	CAD	P28482	MAPK1	T166	R168Q	168	Missense	proximal	2	no	15.983	15.692	EPSD	TCGA;ICGC;COSMIC;CCLE	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P27708	CAD	P28482	MAPK1	T456	Y451C	451	Missense	distal	-5	no	15.215	15.287	PhosphoSitePlus	TCGA;ICGC;COSMIC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P27708	CAD	P28482	MAPK1	T456	L453V	453	Missense	distal	-3	no	15.215	15.291	PhosphoSitePlus	TCGA;ICGC;COSMIC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P27708	CAD	P28482	MAPK1	T456	Q462H	462	Missense	distal	6	no	15.215	15.197	PhosphoSitePlus	TCGA;ICGC;COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P27708	CAD	P28482	MAPK1	T456	P454S	454	Missense	proximal	-2	no	15.215	12.381	PhosphoSitePlus	TCGA;ICGC;COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P27708	CAD	P28482	MAPK1	T475	R468H	468	Missense	distal	-7	no	8.391	8.380	EPSD	TCGA;ICGC;COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P27708	CAD	P28482	MAPK1	T504	T508I	508	Missense	distal	4	no	14.739	14.686	EPSD	TCGA;ICGC;COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P27708	CAD	P28482	MAPK1	S1038	R1033Q	1033	Missense	distal	-5	no	13.738	13.815	EPSD	TCGA;COSMIC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P27708	CAD	P28482	MAPK1	S1113	A1114T	1114	Missense	proximal	1	no	9.752	8.884	EPSD	TCGA	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P27708	CAD	P28482	MAPK1	S1113	R1109C	1109	Missense	distal	-4	no	9.752	9.114	EPSD	TCGA	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P27708	CAD	P28482	MAPK1	S1321	N1324D	1324	Missense	distal	3	no	9.188	9.283	EPSD	TCGA;COSMIC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P27708	CAD	P28482	MAPK1	S1823	E1829D	1829	Missense	distal	6	no	11.174	11.095	EPSD	TCGA;COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P27708	CAD	P28482	MAPK1	T1827	E1829D	1829	Missense	proximal	2	no	8.565	8.617	EPSD	TCGA;COSMIC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P27708	CAD	P28482	MAPK1	T1833	R1838H	1838	Missense	distal	5	no	15.625	15.449	EPSD	TCGA;COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P27708	CAD	P28482	MAPK1	T1833	R1838L	1838	Missense	distal	5	no	15.625	15.362	EPSD	TCGA;COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P27708	CAD	P28482	MAPK1	T1833	E1835Q	1835	Missense	proximal	2	no	15.625	15.515	EPSD	TCGA;COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P27708	CAD	P28482	MAPK1	T1833	P1837H	1837	Missense	distal	4	no	15.625	15.450	EPSD	TCGA	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P27708	CAD	P28482	MAPK1	T1833	G1840D	1840	Missense	distal	7	no	15.625	15.553	EPSD	TCGA;COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P27708	CAD	P28482	MAPK1	T1833	E1829D	1829	Missense	distal	-4	no	15.625	15.640	EPSD	TCGA;COSMIC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P27708	CAD	P28482	MAPK1	T1884	G1887C	1887	Missense	distal	3	no	11.136	11.225	EPSD	TCGA;COSMIC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P27708	CAD	P28482	MAPK1	T1884	L1881P	1881	Missense	distal	-3	no	11.136	11.520	EPSD	TCGA;COSMIC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P27708	CAD	P28482	MAPK1	T1884	G1883R	1883	Missense	proximal	-1	no	11.136	11.171	EPSD	TCGA;COSMIC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P27708	CAD	P28482	MAPK1	S1900	P1901H	1901	Missense	proximal	1	no	11.600	3.776	EPSD	TCGA;COSMIC	8.102	Loss
CMGC_MAPK_ERK1_MAPK1_ST	P27708	CAD	P28482	MAPK1	S1900	A1899T	1899	Missense	proximal	-1	no	11.600	11.594	EPSD	TCGA;COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P27708	CAD	P28482	MAPK1	T1906	P1901H	1901	Missense	distal	-5	no	13.897	14.022	EPSD	TCGA;COSMIC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P27708	CAD	P28482	MAPK1	T1906	A1899T	1899	Missense	distal	-7	no	13.897	13.883	EPSD	TCGA;COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q00613	HSF1	P28482	MAPK1	S244	S250C	250	Missense	distal	6	no	13.950	13.083	EPSD	TCGA;COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q00613	HSF1	P28482	MAPK1	S275	P276L	276	Missense	proximal	1	no	17.140	8.330	EPSD	TCGA;COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q00613	HSF1	P28482	MAPK1	S275	M277V	277	Missense	proximal	2	no	17.140	17.277	EPSD	TCGA;COSMIC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q00613	HSF1	P28482	MAPK1	S279	P276L	276	Missense	distal	-3	no	12.370	11.987	EPSD	TCGA;COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q00613	HSF1	P28482	MAPK1	S279	E286K	286	Missense	distal	7	no	12.370	12.378	EPSD	TCGA;COSMIC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q00613	HSF1	P28482	MAPK1	S279	M277V	277	Missense	proximal	-2	no	12.370	14.512	EPSD	TCGA;COSMIC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q00613	HSF1	P28482	MAPK1	S290	R296C	296	Missense	distal	6	no	8.815	8.055	EPSD	TCGA;COSMIC	8.102	Loss
CMGC_MAPK_ERK1_MAPK1_ST	Q00613	HSF1	P28482	MAPK1	S290	P288L	288	Missense	proximal	-2	no	8.815	6.898	EPSD	TCGA;COSMIC	8.102	Loss
CMGC_MAPK_ERK1_MAPK1_ST	Q00613	HSF1	P28482	MAPK1	S290	E286K	286	Missense	distal	-4	no	8.815	8.833	EPSD	TCGA;COSMIC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q00613	HSF1	P28482	MAPK1	S292	R296C	296	Missense	distal	4	no	14.238	13.979	EPSD	TCGA;COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q00613	HSF1	P28482	MAPK1	S292	P288L	288	Missense	distal	-4	no	14.238	13.934	EPSD	TCGA;COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q00613	HSF1	P28482	MAPK1	S292	E286K	286	Missense	distal	-6	no	14.238	14.212	EPSD	TCGA;COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q00613	HSF1	P28482	MAPK1	S303	E300Q	300	Missense	distal	-3	no	17.219	17.102	EPSD	TCGA	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q00613	HSF1	P28482	MAPK1	S303	R296C	296	Missense	distal	-7	no	17.219	17.187	EPSD	TCGA;COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q00613	HSF1	P28482	MAPK1	S307	E300Q	300	Missense	distal	-7	no	15.590	15.588	EPSD	TCGA	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q00613	HSF1	P28482	MAPK1	S314	R317H	317	Missense	distal	3	no	14.840	14.883	EPSD	TCGA;COSMIC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q00613	HSF1	P28482	MAPK1	S314	S320F	320	Missense	distal	6	no	14.840	14.399	EPSD	TCGA;COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q00613	HSF1	P28482	MAPK1	S326	D332Y	332	Missense	distal	6	no	15.123	14.550	PhosphoSitePlus	TCGA;COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q00613	HSF1	P28482	MAPK1	S326	T323I	323	Missense	distal	-3	no	15.123	14.891	PhosphoSitePlus	TCGA;COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q00613	HSF1	P28482	MAPK1	S326	S320F	320	Missense	distal	-6	no	15.123	15.039	PhosphoSitePlus	TCGA;COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q00613	HSF1	P28482	MAPK1	S326	A329T	329	Missense	distal	3	no	15.123	15.107	PhosphoSitePlus	TCGA;COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q00613	HSF1	P28482	MAPK1	S326	S333F	333	Missense	distal	7	no	15.123	15.471	PhosphoSitePlus	TCGA;COSMIC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q00613	HSF1	P28482	MAPK1	S326	P327L	327	Missense	proximal	1	no	15.123	6.314	PhosphoSitePlus	TCGA	8.102	Loss
CMGC_MAPK_ERK1_MAPK1_ST	Q00613	HSF1	P28482	MAPK1	S363	P364S	364	Missense	proximal	1	no	16.964	7.569	EPSD	TCGA;COSMIC	8.102	Loss
CMGC_MAPK_ERK1_MAPK1_ST	Q00613	HSF1	P28482	MAPK1	S368	P364S	364	Missense	distal	-4	no	8.326	8.242	EPSD	TCGA;COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q00613	HSF1	P28482	MAPK1	T369	P364S	364	Missense	distal	-5	no	12.803	12.878	EPSD	TCGA;COSMIC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q00613	HSF1	P28482	MAPK1	S419	P420L	420	Missense	proximal	1	no	14.430	5.620	EPSD	TCGA;ICGC;COSMIC	8.102	Loss
CMGC_MAPK_ERK1_MAPK1_ST	Q00613	HSF1	P28482	MAPK1	S444	E441K	441	Missense	distal	-3	no	16.077	15.999	EPSD	TCGA;COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q00613	HSF1	P28482	MAPK1	S458	E453K	453	Missense	distal	-5	no	15.044	15.021	EPSD	TCGA;COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q00613	HSF1	P28482	MAPK1	S513	A507V	507	Missense	distal	-6	no	8.309	8.262	EPSD	TCGA;ICGC;COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q969H0	FBXW7	P28482	MAPK1	S26	M33I	33	Missense	distal	7	no	8.758	8.946	EPSD	TCGA;ICGC;COSMIC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q969H0	FBXW7	P28482	MAPK1	S372	G368E	368	Missense	distal	-4	no	14.301	14.622	EPSD	TCGA;ICGC;COSMIC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q969H0	FBXW7	P28482	MAPK1	S372	K374Q	374	Missense	proximal	2	no	14.301	14.191	EPSD	TCGA	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q969H0	FBXW7	P28482	MAPK1	S372	W365S	365	Missense	distal	-7	no	14.301	14.353	EPSD	TCGA;ICGC;COSMIC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q969H0	FBXW7	P28482	MAPK1	S372	P373S	373	Missense	proximal	1	no	14.301	4.906	EPSD	TCGA;ICGC;COSMIC	8.102	Loss
CMGC_MAPK_ERK1_MAPK1_ST	Q969H0	FBXW7	P28482	MAPK1	S688	R689W	689	Missense	proximal	1	no	8.071	10.349	EPSD	TCGA;ICGC;COSMIC;GDSC;CCLE	8.102	Gain
CMGC_MAPK_ERK1_MAPK1_ST	Q969H0	FBXW7	P28482	MAPK1	S688	R689Q	689	Missense	proximal	1	no	8.071	9.232	EPSD	TCGA;ICGC;COSMIC	8.102	Gain
CMGC_MAPK_ERK1_MAPK1_ST	Q15750	TAB1	P28482	MAPK1	S16	D20Y	20	Missense	distal	4	no	10.112	10.015	EPSD	TCGA	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q15750	TAB1	P28482	MAPK1	S16	W17C	17	Missense	proximal	1	no	10.112	4.040	EPSD	TCGA;ICGC;COSMIC	8.102	Loss
CMGC_MAPK_ERK1_MAPK1_ST	Q15750	TAB1	P28482	MAPK1	T431	E429K	429	Missense	proximal	-2	no	12.012	11.972	EPSD	TCGA;ICGC;COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q15750	TAB1	P28482	MAPK1	T431	A430T	430	Missense	proximal	-1	no	12.012	12.007	EPSD	TCGA;ICGC;COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q15750	TAB1	P28482	MAPK1	T431	T433I	433	Missense	proximal	2	no	12.012	11.892	EPSD	TCGA;ICGC;COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q15750	TAB1	P28482	MAPK1	S438	T433I	433	Missense	distal	-5	no	13.407	13.514	PhosphoSitePlus	TCGA;ICGC;COSMIC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q15750	TAB1	P28482	MAPK1	S492	V493M	493	Missense	proximal	1	no	8.195	3.032	EPSD	TCGA;ICGC;COSMIC	8.102	Loss
CMGC_MAPK_ERK1_MAPK1_ST	Q15750	TAB1	P28482	MAPK1	S492	L490P	490	Missense	proximal	-2	no	8.195	10.112	EPSD	TCGA;ICGC;COSMIC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q9Y6K1	DNMT3A	P28482	MAPK1	S15	A17V	17	Missense	proximal	2	no	8.539	8.616	EPSD	TCGA;ICGC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q9Y6K1	DNMT3A	P28482	MAPK1	S75	P76S	76	Missense	proximal	1	no	11.951	2.556	EPSD	TCGA;ICGC;COSMIC	8.102	Loss
CMGC_MAPK_ERK1_MAPK1_ST	Q9Y6K1	DNMT3A	P28482	MAPK1	S105	P106S	106	Missense	proximal	1	no	14.989	5.594	EPSD	TCGA;ICGC;COSMIC	8.102	Loss
CMGC_MAPK_ERK1_MAPK1_ST	Q9Y6K1	DNMT3A	P28482	MAPK1	S105	P106L	106	Missense	proximal	1	no	14.989	6.179	EPSD	TCGA;ICGC;COSMIC	8.102	Loss
CMGC_MAPK_ERK1_MAPK1_ST	Q9Y6K1	DNMT3A	P28482	MAPK1	T138	R143Q	143	Missense	distal	5	no	12.941	12.771	EPSD	TCGA;ICGC;COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q9Y6K1	DNMT3A	P28482	MAPK1	S243	A242V	242	Missense	proximal	-1	no	13.554	13.565	EPSD	TCGA;COSMIC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q9Y6K1	DNMT3A	P28482	MAPK1	S255	A259G	259	Missense	distal	4	no	17.002	17.046	PhosphoSitePlus	TCGA;COSMIC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q9Y6K1	DNMT3A	P28482	MAPK1	S255	V258M	258	Missense	distal	3	no	17.002	17.029	PhosphoSitePlus	TCGA;COSMIC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q9Y6K1	DNMT3A	P28482	MAPK1	T261	V265M	265	Missense	distal	4	no	13.031	12.942	EPSD	TCGA;ICGC;COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q9Y6K1	DNMT3A	P28482	MAPK1	T261	A259G	259	Missense	proximal	-2	no	13.031	12.983	EPSD	TCGA;COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q9Y6K1	DNMT3A	P28482	MAPK1	T261	V258M	258	Missense	distal	-3	no	13.031	12.900	EPSD	TCGA;COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q9UBN7	HDAC6	P28482	MAPK1	S16	R14Q	14	Missense	proximal	-2	no	8.614	7.439	EPSD	TCGA;ICGC;COSMIC	8.102	Loss
CMGC_MAPK_ERK1_MAPK1_ST	Q9UBN7	HDAC6	P28482	MAPK1	S412	P408H	408	Missense	distal	-4	no	14.167	13.926	EPSD	TCGA;COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q9UBN7	HDAC6	P28482	MAPK1	T527	R529L	529	Missense	proximal	2	no	12.432	12.171	EPSD	TCGA;COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q9UBN7	HDAC6	P28482	MAPK1	T1021	G1014R	1014	Missense	distal	-7	no	14.144	14.157	EPSD	TCGA;COSMIC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q9UBN7	HDAC6	P28482	MAPK1	T1021	E1017K	1017	Missense	distal	-4	no	14.144	14.162	EPSD	TCGA;COSMIC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q9UBN7	HDAC6	P28482	MAPK1	T1031	S1035L	1035	Missense	distal	4	no	13.802	13.692	PhosphoSitePlus	TCGA;COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q9UBN7	HDAC6	P28482	MAPK1	T1031	Q1030H	1030	Missense	proximal	-1	no	13.802	13.800	PhosphoSitePlus	TCGA	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q9UBN7	HDAC6	P28482	MAPK1	T1034	S1035L	1035	Missense	proximal	1	no	8.515	9.100	EPSD	TCGA;COSMIC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q9UBN7	HDAC6	P28482	MAPK1	T1034	Q1030H	1030	Missense	distal	-4	no	8.515	8.466	EPSD	TCGA	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q9UBN7	HDAC6	P28482	MAPK1	S1035	S1035L	1035	Missense	central	0	yes	16.449	0.000	EPSD	TCGA;COSMIC	8.102	Loss
CMGC_MAPK_ERK1_MAPK1_ST	Q9UBN7	HDAC6	P28482	MAPK1	T1041	S1035L	1035	Missense	distal	-6	no	11.481	11.415	EPSD	TCGA;COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q9UBN7	HDAC6	P28482	MAPK1	T1041	Q1043H	1043	Missense	proximal	2	no	11.481	11.529	EPSD	TCGA;COSMIC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P33981	TTK	P28482	MAPK1	S214	G217S	217	Missense	distal	3	no	8.447	8.433	EPSD	TCGA;ICGC;COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P33981	TTK	P28482	MAPK1	S281	T288I	288	Missense	distal	7	no	15.075	15.471	EPSD	TCGA;ICGC;COSMIC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P33981	TTK	P28482	MAPK1	T453	S449Y	449	Missense	distal	-4	no	8.512	7.923	EPSD	TCGA;COSMIC	8.102	Loss
CMGC_MAPK_ERK1_MAPK1_ST	P33981	TTK	P28482	MAPK1	T468	P469L	469	Missense	proximal	1	no	12.759	3.949	EPSD	TCGA;COSMIC;GDSC	8.102	Loss
CMGC_MAPK_ERK1_MAPK1_ST	P33981	TTK	P28482	MAPK1	T468	K472N	472	Missense	distal	4	no	12.759	12.734	EPSD	TCGA	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P33981	TTK	P28482	MAPK1	T675	T676A	676	Missense	proximal	1	no	7.611	8.479	EPSD	TCGA;COSMIC	8.102	Gain
CMGC_MAPK_ERK1_MAPK1_ST	P33981	TTK	P28482	MAPK1	S821	G814C	814	Missense	distal	-7	no	13.032	13.013	PhosphoSitePlus	TCGA;COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P33981	TTK	P28482	MAPK1	S821	S824F	824	Missense	distal	3	no	13.032	13.094	PhosphoSitePlus	TCGA;COSMIC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P33981	TTK	P28482	MAPK1	S821	L816R	816	Missense	distal	-5	no	13.032	12.931	PhosphoSitePlus	TCGA;COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P33981	TTK	P28482	MAPK1	S821	S821Y	821	Missense	central	0	yes	13.032	0.000	PhosphoSitePlus	TCGA;COSMIC	8.102	Loss
CMGC_MAPK_ERK1_MAPK1_ST	P33981	TTK	P28482	MAPK1	S844	G839S	839	Missense	distal	-5	no	9.015	9.022	EPSD	TCGA;COSMIC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q86UR1	NOXA1	P28482	MAPK1	S239	S239F	239	Missense	central	0	yes	9.791	0.000	EPSD	TCGA;ICGC	8.102	Loss
CMGC_MAPK_ERK1_MAPK1_ST	Q86UR1	NOXA1	P28482	MAPK1	S282	G289E	289	Missense	distal	7	no	15.873	15.746	PhosphoSitePlus	TCGA;ICGC;COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q86UR1	NOXA1	P28482	MAPK1	S470	R466Q	466	Missense	distal	-4	no	11.822	11.719	EPSD	TCGA;COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P47712	PLA2G4A	P28482	MAPK1	T41	M38I	38	Missense	distal	-3	no	16.542	16.539	EPSD	TCGA;COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P47712	PLA2G4A	P28482	MAPK1	T41	L39I	39	Missense	proximal	-2	no	16.542	16.565	EPSD	TCGA;COSMIC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P47712	PLA2G4A	P28482	MAPK1	T41	P44S	44	Missense	distal	3	no	16.542	16.612	EPSD	TCGA;ICGC;COSMIC;GDSC;CCLE	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P47712	PLA2G4A	P28482	MAPK1	T53	P54S	54	Missense	proximal	1	no	15.064	5.669	EPSD	TCGA;ICGC;COSMIC	8.102	Loss
CMGC_MAPK_ERK1_MAPK1_ST	P47712	PLA2G4A	P28482	MAPK1	T53	T52A	52	Missense	proximal	-1	no	15.064	15.069	EPSD	TCGA;ICGC;COSMIC;GDSC;CCLE	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P47712	PLA2G4A	P28482	MAPK1	S56	F63L	63	Missense	distal	7	no	8.269	8.210	EPSD	TCGA;ICGC;COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P47712	PLA2G4A	P28482	MAPK1	S56	P54S	54	Missense	proximal	-2	no	8.269	5.434	EPSD	TCGA;ICGC;COSMIC	8.102	Loss
CMGC_MAPK_ERK1_MAPK1_ST	P47712	PLA2G4A	P28482	MAPK1	S56	R61K	61	Missense	distal	5	no	8.269	8.133	EPSD	TCGA;ICGC;COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P47712	PLA2G4A	P28482	MAPK1	S56	T52A	52	Missense	distal	-4	no	8.269	8.289	EPSD	TCGA;ICGC;COSMIC;GDSC;CCLE	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P47712	PLA2G4A	P28482	MAPK1	T268	P263H	263	Missense	distal	-5	no	13.910	14.035	EPSD	TCGA;COSMIC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P47712	PLA2G4A	P28482	MAPK1	S508	S515F	515	Missense	distal	7	no	8.279	8.627	EPSD	TCGA;ICGC;COSMIC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P47712	PLA2G4A	P28482	MAPK1	S515	D517V	517	Missense	proximal	2	no	8.506	8.469	EPSD	TCGA	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P47712	PLA2G4A	P28482	MAPK1	S515	E520K	520	Missense	distal	5	no	8.506	8.447	EPSD	TCGA;ICGC;COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P47712	PLA2G4A	P28482	MAPK1	S515	S515F	515	Missense	central	0	yes	8.506	0.000	EPSD	TCGA;ICGC;COSMIC	8.102	Loss
CMGC_MAPK_ERK1_MAPK1_ST	P47712	PLA2G4A	P28482	MAPK1	S724	R725H	725	Missense	proximal	1	no	6.821	8.652	EPSD	TCGA;ICGC;COSMIC	8.102	Gain
CMGC_MAPK_ERK1_MAPK1_ST	Q12931	TRAP1	P28482	MAPK1	T40	A41S	41	Missense	proximal	1	no	8.206	6.441	EPSD	TCGA;ICGC	8.102	Loss
CMGC_MAPK_ERK1_MAPK1_ST	Q12931	TRAP1	P28482	MAPK1	T40	A41V	41	Missense	proximal	1	no	8.206	6.296	EPSD	TCGA;ICGC;COSMIC	8.102	Loss
CMGC_MAPK_ERK1_MAPK1_ST	Q12931	TRAP1	P28482	MAPK1	T40	R38M	38	Missense	proximal	-2	no	8.206	6.010	EPSD	TCGA;ICGC	8.102	Loss
CMGC_MAPK_ERK1_MAPK1_ST	Q12931	TRAP1	P28482	MAPK1	S282	V281I	281	Missense	proximal	-1	no	9.403	9.363	EPSD	TCGA;ICGC;COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q12931	TRAP1	P28482	MAPK1	S361	R368H	368	Missense	distal	7	no	7.946	8.165	EPSD	TCGA;ICGC;COSMIC;GDSC	8.102	Gain
CMGC_MAPK_ERK1_MAPK1_ST	Q12931	TRAP1	P28482	MAPK1	S511	M517T	517	Missense	distal	6	no	12.223	12.446	PhosphoSitePlus	TCGA;ICGC;COSMIC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q12931	TRAP1	P28482	MAPK1	S568	A571T	571	Missense	distal	3	no	10.208	10.191	EPSD	TCGA;ICGC;COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P19419	ELK1	P28482	MAPK1	T133	P134L	134	Missense	proximal	1	no	14.506	5.697	EPSD	TCGA;ICGC	8.102	Loss
CMGC_MAPK_ERK1_MAPK1_ST	P19419	ELK1	P28482	MAPK1	T161	S156L	156	Missense	distal	-5	no	8.042	8.117	EPSD	TCGA;ICGC;COSMIC	8.102	Gain
CMGC_MAPK_ERK1_MAPK1_ST	P19419	ELK1	P28482	MAPK1	S200	S194L	194	Missense	distal	-6	no	13.663	13.598	EPSD	TCGA;ICGC;COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P19419	ELK1	P28482	MAPK1	S200	S196R	196	Missense	distal	-4	no	13.663	13.658	EPSD	TCGA;ICGC;COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P19419	ELK1	P28482	MAPK1	S200	P201L	201	Missense	proximal	1	no	13.663	4.854	EPSD	TCGA;ICGC;COSMIC	8.102	Loss
CMGC_MAPK_ERK1_MAPK1_ST	P19419	ELK1	P28482	MAPK1	S200	G195R	195	Missense	distal	-5	no	13.663	13.643	EPSD	TCGA;COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P19419	ELK1	P28482	MAPK1	S202	S196R	196	Missense	distal	-6	no	13.716	13.750	EPSD	TCGA;ICGC;COSMIC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P19419	ELK1	P28482	MAPK1	S202	P201L	201	Missense	proximal	-1	no	13.716	13.656	EPSD	TCGA;ICGC;COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P19419	ELK1	P28482	MAPK1	S202	G195R	195	Missense	distal	-7	no	13.716	13.729	EPSD	TCGA;COSMIC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P19419	ELK1	P28482	MAPK1	T222	P224S	224	Missense	proximal	2	no	14.384	14.356	EPSD	TCGA;ICGC;COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P19419	ELK1	P28482	MAPK1	T222	E225K	225	Missense	distal	3	no	14.384	14.391	EPSD	TCGA;ICGC;COSMIC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P19419	ELK1	P28482	MAPK1	S304	S308C	308	Missense	distal	4	no	13.262	12.980	EPSD	TCGA;ICGC;COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P19419	ELK1	P28482	MAPK1	S304	A301V	301	Missense	distal	-3	no	13.262	13.321	EPSD	TCGA;ICGC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P19419	ELK1	P28482	MAPK1	S304	G298V	298	Missense	distal	-6	no	13.262	13.218	EPSD	TCGA;ICGC;COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P19419	ELK1	P28482	MAPK1	S304	S303Y	303	Missense	proximal	-1	no	13.262	13.230	EPSD	TCGA;ICGC;COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P19419	ELK1	P28482	MAPK1	S324	S324N	324	Missense	central	0	yes	16.645	0.000	EPSD	TCGA;ICGC;COSMIC	8.102	Loss
CMGC_MAPK_ERK1_MAPK1_ST	P19419	ELK1	P28482	MAPK1	S324	P325L	325	Missense	proximal	1	no	16.645	7.835	EPSD	TCGA;ICGC	8.102	Loss
CMGC_MAPK_ERK1_MAPK1_ST	P19419	ELK1	P28482	MAPK1	T353	A351V	351	Missense	proximal	-2	no	12.838	14.112	EPSD	TCGA;ICGC;COSMIC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P19419	ELK1	P28482	MAPK1	T368	L372Q	372	Missense	distal	4	no	15.156	15.168	EPSD	TCGA;ICGC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P19419	ELK1	P28482	MAPK1	S383	W379C	379	Missense	distal	-4	no	13.857	14.162	PhosphoSitePlus	TCGA	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P19419	ELK1	P28482	MAPK1	S383	F378L	378	Missense	distal	-5	no	13.857	13.844	PhosphoSitePlus	TCGA;ICGC;COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P19419	ELK1	P28482	MAPK1	S389	S383T	383	Missense	distal	-6	no	13.963	13.940	EPSD	TCGA;COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P19419	ELK1	P28482	MAPK1	S389	A391D	391	Missense	proximal	2	no	13.963	14.077	EPSD	TCGA;ICGC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P19419	ELK1	P28482	MAPK1	S422	K427R	427	Missense	distal	5	no	18.830	18.965	EPSD	TCGA;ICGC;COSMIC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q92908	GATA6	P28482	MAPK1	T34	P36L	36	Missense	proximal	2	no	15.730	15.583	EPSD	TCGA;ICGC;COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q92908	GATA6	P28482	MAPK1	S37	P36L	36	Missense	proximal	-1	no	17.103	17.044	EPSD	TCGA;ICGC;COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q92908	GATA6	P28482	MAPK1	T62	A69V	69	Missense	distal	7	no	9.735	9.836	EPSD	TCGA;ICGC;COSMIC;GDSC;CCLE	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q92908	GATA6	P28482	MAPK1	S436	R439W	439	Missense	distal	3	no	8.986	9.135	EPSD	TCGA;ICGC;COSMIC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q92908	GATA6	P28482	MAPK1	T515	S520C	520	Missense	distal	5	no	15.246	14.846	EPSD	TCGA;ICGC;COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q92908	GATA6	P28482	MAPK1	T515	P516L	516	Missense	proximal	1	no	15.246	6.436	EPSD	TCGA;ICGC;COSMIC	8.102	Loss
CMGC_MAPK_ERK1_MAPK1_ST	Q92908	GATA6	P28482	MAPK1	S531	N529K	529	Missense	proximal	-2	no	13.901	14.301	EPSD	TCGA;ICGC;COSMIC;GDSC;CCLE	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q92908	GATA6	P28482	MAPK1	S531	N529H	529	Missense	proximal	-2	no	13.901	13.966	EPSD	TCGA;ICGC;COSMIC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q92908	GATA6	P28482	MAPK1	S531	A538T	538	Missense	distal	7	no	13.901	13.872	EPSD	TCGA;ICGC;COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q92908	GATA6	P28482	MAPK1	T534	N529K	529	Missense	distal	-5	no	9.999	9.975	EPSD	TCGA;ICGC;COSMIC;GDSC;CCLE	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q92908	GATA6	P28482	MAPK1	T534	N529H	529	Missense	distal	-5	no	9.999	10.098	EPSD	TCGA;ICGC;COSMIC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q92908	GATA6	P28482	MAPK1	T534	G540R	540	Missense	distal	6	no	9.999	9.969	EPSD	TCGA;ICGC;COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q92908	GATA6	P28482	MAPK1	T534	A538T	538	Missense	distal	4	no	9.999	9.979	EPSD	TCGA;ICGC;COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P04637	TP53	P28482	MAPK1	S33	P27S	27	Missense	distal	-6	no	13.820	13.794	EPSD	TCGA;ICGC;COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P04637	TP53	P28482	MAPK1	S33	P27L	27	Missense	distal	-6	no	13.820	13.728	EPSD	TCGA;ICGC;COSMIC;GDSC;CCLE	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P04637	TP53	P28482	MAPK1	S46	D48N	48	Missense	proximal	2	no	11.716	11.655	EPSD	TCGA;ICGC;COSMIC;GDSC;CCLE	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P04637	TP53	P28482	MAPK1	T81	A79V	79	Missense	proximal	-2	no	14.705	15.979	EPSD	TCGA;ICGC;COSMIC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P04637	TP53	P28482	MAPK1	T81	P77L	77	Missense	distal	-4	no	14.705	14.401	EPSD	TCGA;ICGC;COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P04637	TP53	P28482	MAPK1	T81	P82L	82	Missense	proximal	1	no	14.705	5.896	EPSD	TCGA;ICGC;COSMIC	8.102	Loss
CMGC_MAPK_ERK1_MAPK1_ST	P04637	TP53	P28482	MAPK1	T81	A74T	74	Missense	distal	-7	no	14.705	14.691	EPSD	TCGA;ICGC;COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P04637	TP53	P28482	MAPK1	S127	K132N	132	Missense	distal	5	no	14.148	14.179	EPSD	TCGA;ICGC;COSMIC;GDSC;CCLE	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P04637	TP53	P28482	MAPK1	S127	S121Y	121	Missense	distal	-6	no	14.148	14.034	EPSD	TCGA;ICGC;COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P04637	TP53	P28482	MAPK1	S127	M133K	133	Missense	distal	6	no	14.148	14.638	EPSD	TCGA;ICGC;COSMIC;CCLE	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P04637	TP53	P28482	MAPK1	S127	K132E	132	Missense	distal	5	no	14.148	14.207	EPSD	TCGA;ICGC;COSMIC;GDSC;CCLE	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P04637	TP53	P28482	MAPK1	S127	Y126C	126	Missense	proximal	-1	no	14.148	14.101	EPSD	TCGA;ICGC;COSMIC;GDSC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P04637	TP53	P28482	MAPK1	S127	S127P	127	Missense	central	0	yes	14.148	0.000	EPSD	TCGA;ICGC;COSMIC;GDSC;CCLE	8.102	Loss
CMGC_MAPK_ERK1_MAPK1_ST	P04637	TP53	P28482	MAPK1	S127	Y126N	126	Missense	proximal	-1	no	14.148	14.229	EPSD	TCGA;ICGC;COSMIC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P04637	TP53	P28482	MAPK1	S127	L130V	130	Missense	distal	3	no	14.148	14.116	EPSD	TCGA;ICGC;COSMIC;GDSC;CCLE	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P04637	TP53	P28482	MAPK1	S127	K132T	132	Missense	distal	5	no	14.148	14.178	EPSD	TCGA;ICGC;COSMIC;GDSC;CCLE	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P04637	TP53	P28482	MAPK1	S127	S127Y	127	Missense	central	0	yes	14.148	0.000	EPSD	TCGA;ICGC;COSMIC	8.102	Loss
CMGC_MAPK_ERK1_MAPK1_ST	P04637	TP53	P28482	MAPK1	S127	S127F	127	Missense	central	0	yes	14.148	0.000	EPSD	TCGA;ICGC;COSMIC;CCLE	8.102	Loss
CMGC_MAPK_ERK1_MAPK1_ST	P04637	TP53	P28482	MAPK1	S127	M133R	133	Missense	distal	6	no	14.148	14.474	EPSD	TCGA;ICGC;COSMIC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P04637	TP53	P28482	MAPK1	S127	K132R	132	Missense	distal	5	no	14.148	14.283	EPSD	TCGA;ICGC;COSMIC;GDSC;CCLE	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P04637	TP53	P28482	MAPK1	S127	F134L	134	Missense	distal	7	no	14.148	14.089	EPSD	TCGA;ICGC;COSMIC;CCLE	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P04637	TP53	P28482	MAPK1	S127	Y126S	126	Missense	proximal	-1	no	14.148	14.180	EPSD	TCGA;ICGC;COSMIC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P04637	TP53	P28482	MAPK1	S127	L130P	130	Missense	distal	3	no	14.148	14.058	EPSD	TCGA;ICGC;COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P04637	TP53	P28482	MAPK1	S127	L130F	130	Missense	distal	3	no	14.148	14.190	EPSD	TCGA;ICGC;COSMIC;CCLE	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P04637	TP53	P28482	MAPK1	S127	F134V	134	Missense	distal	7	no	14.148	14.083	EPSD	TCGA;ICGC;COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P04637	TP53	P28482	MAPK1	S127	T125M	125	Missense	proximal	-2	no	14.148	12.833	EPSD	TCGA;ICGC;COSMIC;GDSC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P04637	TP53	P28482	MAPK1	S127	Y126D	126	Missense	proximal	-1	no	14.148	14.168	EPSD	TCGA;ICGC;COSMIC;GDSC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P04637	TP53	P28482	MAPK1	S127	K120E	120	Missense	distal	-7	no	14.148	14.155	EPSD	TCGA;ICGC;COSMIC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P04637	TP53	P28482	MAPK1	S127	N131S	131	Missense	distal	4	no	14.148	14.185	EPSD	TCGA;ICGC;COSMIC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P04637	TP53	P28482	MAPK1	S127	T125P	125	Missense	proximal	-2	no	14.148	16.847	EPSD	TCGA;ICGC;COSMIC;CCLE	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P04637	TP53	P28482	MAPK1	S127	S127C	127	Missense	central	0	yes	14.148	0.000	EPSD	TCGA;ICGC;COSMIC;CCLE	8.102	Loss
CMGC_MAPK_ERK1_MAPK1_ST	P04637	TP53	P28482	MAPK1	S127	N131I	131	Missense	distal	4	no	14.148	14.019	EPSD	TCGA;ICGC;COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P04637	TP53	P28482	MAPK1	S127	Y126H	126	Missense	proximal	-1	no	14.148	14.180	EPSD	TCGA;ICGC;COSMIC;GDSC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P04637	TP53	P28482	MAPK1	S127	K132Q	132	Missense	distal	5	no	14.148	14.113	EPSD	TCGA;ICGC;COSMIC;GDSC;CCLE	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P04637	TP53	P28482	MAPK1	S127	L130R	130	Missense	distal	3	no	14.148	14.104	EPSD	TCGA;ICGC;COSMIC;CCLE	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P04637	TP53	P28482	MAPK1	T150	W146S	146	Missense	distal	-4	no	11.263	12.211	EPSD	TCGA;ICGC;COSMIC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P04637	TP53	P28482	MAPK1	T150	P152L	152	Missense	proximal	2	no	11.263	11.116	EPSD	TCGA;ICGC;COSMIC;GDSC;CCLE	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P04637	TP53	P28482	MAPK1	T150	D148N	148	Missense	proximal	-2	no	11.263	11.745	EPSD	TCGA;ICGC;COSMIC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P04637	TP53	P28482	MAPK1	T150	P151H	151	Missense	proximal	1	no	11.263	3.439	EPSD	TCGA;ICGC;COSMIC;GDSC;CCLE	8.102	Loss
CMGC_MAPK_ERK1_MAPK1_ST	P04637	TP53	P28482	MAPK1	T150	P151A	151	Missense	proximal	1	no	11.263	3.633	EPSD	TCGA;ICGC;COSMIC;CCLE	8.102	Loss
CMGC_MAPK_ERK1_MAPK1_ST	P04637	TP53	P28482	MAPK1	T150	R156P	156	Missense	distal	6	no	11.263	11.370	EPSD	TCGA;ICGC;COSMIC;GDSC;CCLE	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P04637	TP53	P28482	MAPK1	T150	V143A	143	Missense	distal	-7	no	11.263	11.280	EPSD	TCGA;ICGC;COSMIC;GDSC;CCLE	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P04637	TP53	P28482	MAPK1	T150	P151S	151	Missense	proximal	1	no	11.263	1.868	EPSD	TCGA;ICGC;COSMIC;GDSC;CCLE	8.102	Loss
CMGC_MAPK_ERK1_MAPK1_ST	P04637	TP53	P28482	MAPK1	T150	V157F	157	Missense	distal	7	no	11.263	11.328	EPSD	TCGA;ICGC;COSMIC;GDSC;CCLE	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P04637	TP53	P28482	MAPK1	T150	V157G	157	Missense	distal	7	no	11.263	11.049	EPSD	TCGA;ICGC;COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P04637	TP53	P28482	MAPK1	T150	V157D	157	Missense	distal	7	no	11.263	10.976	EPSD	TCGA;ICGC;COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P04637	TP53	P28482	MAPK1	T150	L145R	145	Missense	distal	-5	no	11.263	11.162	EPSD	TCGA;ICGC;COSMIC;GDSC;CCLE	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P04637	TP53	P28482	MAPK1	T150	T155I	155	Missense	distal	5	no	11.263	11.020	EPSD	TCGA;ICGC;COSMIC;CCLE	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P04637	TP53	P28482	MAPK1	T150	V143M	143	Missense	distal	-7	no	11.263	11.261	EPSD	TCGA;ICGC;COSMIC;GDSC;CCLE	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P04637	TP53	P28482	MAPK1	T150	T155N	155	Missense	distal	5	no	11.263	11.264	EPSD	TCGA;ICGC;COSMIC;GDSC;CCLE	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P04637	TP53	P28482	MAPK1	T150	P152S	152	Missense	proximal	2	no	11.263	11.235	EPSD	TCGA;ICGC;COSMIC;CCLE	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P04637	TP53	P28482	MAPK1	T150	R156C	156	Missense	distal	6	no	11.263	10.503	EPSD	TCGA;ICGC;COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P04637	TP53	P28482	MAPK1	T150	P151T	151	Missense	proximal	1	no	11.263	2.764	EPSD	TCGA;ICGC;COSMIC	8.102	Loss
CMGC_MAPK_ERK1_MAPK1_ST	P04637	TP53	P28482	MAPK1	T150	T155P	155	Missense	distal	5	no	11.263	11.319	EPSD	TCGA;ICGC;COSMIC;CCLE	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P04637	TP53	P28482	MAPK1	T150	V143G	143	Missense	distal	-7	no	11.263	11.264	EPSD	TCGA;ICGC;COSMIC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P04637	TP53	P28482	MAPK1	T150	P152Q	152	Missense	proximal	2	no	11.263	11.085	EPSD	TCGA;ICGC;COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P04637	TP53	P28482	MAPK1	T150	R156H	156	Missense	distal	6	no	11.263	11.065	EPSD	TCGA;ICGC;COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P04637	TP53	P28482	MAPK1	T150	L145P	145	Missense	distal	-5	no	11.263	11.114	EPSD	TCGA;ICGC;COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P04637	TP53	P28482	MAPK1	T150	Q144L	144	Missense	distal	-6	no	11.263	11.187	EPSD	TCGA;ICGC;COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P04637	TP53	P28482	MAPK1	T150	Q144H	144	Missense	distal	-6	no	11.263	11.204	EPSD	TCGA;ICGC;COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P04637	TP53	P28482	MAPK1	T150	G154V	154	Missense	distal	4	no	11.263	11.213	EPSD	TCGA;ICGC;COSMIC;GDSC;CCLE	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P04637	TP53	P28482	MAPK1	T150	V157L	157	Missense	distal	7	no	11.263	11.269	EPSD	TCGA;ICGC;COSMIC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P04637	TP53	P28482	MAPK1	T150	P151R	151	Missense	proximal	1	no	11.263	1.609	EPSD	TCGA;ICGC;COSMIC	8.102	Loss
CMGC_MAPK_ERK1_MAPK1_ST	P04637	TP53	P28482	MAPK1	T150	Q144P	144	Missense	distal	-6	no	11.263	11.279	EPSD	TCGA;ICGC;COSMIC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P04637	TP53	P28482	MAPK1	T150	V143E	143	Missense	distal	-7	no	11.263	11.287	EPSD	TCGA;ICGC;COSMIC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P04637	TP53	P28482	MAPK1	T150	R156G	156	Missense	distal	6	no	11.263	11.293	EPSD	TCGA;ICGC;COSMIC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P04637	TP53	P28482	MAPK1	T150	P151L	151	Missense	proximal	1	no	11.263	2.454	EPSD	TCGA;ICGC;COSMIC	8.102	Loss
CMGC_MAPK_ERK1_MAPK1_ST	P04637	TP53	P28482	MAPK1	T155	R156P	156	Missense	proximal	1	no	5.464	15.118	EPSD	TCGA;ICGC;COSMIC;GDSC;CCLE	8.102	Gain
CMGC_MAPK_ERK1_MAPK1_ST	P04637	TP53	P28482	MAPK1	S269	C275S	275	Missense	distal	6	no	7.464	8.331	EPSD	TCGA;ICGC;COSMIC	8.102	Gain
CMGC_MAPK_ERK1_MAPK1_ST	P04637	TP53	P28482	MAPK1	S269	R267P	267	Missense	proximal	-2	no	7.464	9.283	EPSD	TCGA;ICGC;COSMIC;GDSC;CCLE	8.102	Gain
CMGC_MAPK_ERK1_MAPK1_ST	P04637	TP53	P28482	MAPK1	S269	C275R	275	Missense	distal	6	no	7.464	8.224	EPSD	TCGA;ICGC;COSMIC	8.102	Gain
CMGC_MAPK_ERK1_MAPK1_ST	P04637	TP53	P28482	MAPK1	S269	C275G	275	Missense	distal	6	no	7.464	8.254	EPSD	TCGA;ICGC;COSMIC;GDSC;CCLE	8.102	Gain
CMGC_MAPK_ERK1_MAPK1_ST	P04637	TP53	P28482	MAPK1	S315	K319N	319	Missense	distal	4	no	13.607	13.583	EPSD	TCGA;ICGC;COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P04637	TP53	P28482	MAPK1	S315	K320E	320	Missense	distal	5	no	13.607	13.667	EPSD	TCGA;ICGC;COSMIC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P04637	TP53	P28482	MAPK1	S315	S315C	315	Missense	central	0	yes	13.607	0.000	EPSD	TCGA;ICGC;COSMIC	8.102	Loss
CMGC_MAPK_ERK1_MAPK1_ST	P04637	TP53	P28482	MAPK1	S376	S376C	376	Missense	central	0	yes	8.969	0.000	EPSD	TCGA;ICGC;COSMIC	8.102	Loss
CMGC_MAPK_ERK1_MAPK1_ST	P04637	TP53	P28482	MAPK1	S376	Q375K	375	Missense	proximal	-1	no	8.969	9.023	EPSD	TCGA;ICGC;COSMIC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q7L5N1	COPS6	P28482	MAPK1	S148	E147K	147	Missense	proximal	-1	no	11.903	11.931	PhosphoSitePlus	TCGA;COSMIC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q14686	NCOA6	P28482	MAPK1	T416	G410V	410	Missense	distal	-6	no	14.203	14.160	EPSD	TCGA;ICGC;COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q14686	NCOA6	P28482	MAPK1	T416	Q419L	419	Missense	distal	3	no	14.203	14.225	EPSD	TCGA;ICGC;COSMIC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q14686	NCOA6	P28482	MAPK1	T416	P417S	417	Missense	proximal	1	no	14.203	4.808	EPSD	TCGA;ICGC;COSMIC	8.102	Loss
CMGC_MAPK_ERK1_MAPK1_ST	Q14686	NCOA6	P28482	MAPK1	S667	P672S	672	Missense	distal	5	no	9.041	9.059	EPSD	TCGA;ICGC;COSMIC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q14686	NCOA6	P28482	MAPK1	S667	P666S	666	Missense	proximal	-1	no	9.041	8.998	EPSD	TCGA;ICGC;COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q14686	NCOA6	P28482	MAPK1	S667	P666L	666	Missense	proximal	-1	no	9.041	8.981	EPSD	TCGA;ICGC;GDSC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q14686	NCOA6	P28482	MAPK1	S673	M677L	677	Missense	distal	4	no	13.034	13.112	EPSD	TCGA;ICGC;COSMIC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q14686	NCOA6	P28482	MAPK1	S673	P672S	672	Missense	proximal	-1	no	13.034	12.991	EPSD	TCGA;ICGC;COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q14686	NCOA6	P28482	MAPK1	S673	P666S	666	Missense	distal	-7	no	13.034	13.030	EPSD	TCGA;ICGC;COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q14686	NCOA6	P28482	MAPK1	S673	P666L	666	Missense	distal	-7	no	13.034	13.022	EPSD	TCGA;ICGC;GDSC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q14686	NCOA6	P28482	MAPK1	T678	M677L	677	Missense	proximal	-1	no	15.371	15.362	EPSD	TCGA;ICGC;COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q14686	NCOA6	P28482	MAPK1	T678	P672S	672	Missense	distal	-6	no	15.371	15.345	EPSD	TCGA;ICGC;COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q14686	NCOA6	P28482	MAPK1	T678	K681R	681	Missense	distal	3	no	15.371	15.420	EPSD	TCGA;ICGC;COSMIC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q14686	NCOA6	P28482	MAPK1	S884	T883R	883	Missense	proximal	-1	no	14.794	14.817	PhosphoSitePlus	TCGA;ICGC;COSMIC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q14686	NCOA6	P28482	MAPK1	S884	N877I	877	Missense	distal	-7	no	14.794	14.764	PhosphoSitePlus	TCGA;ICGC;COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q14686	NCOA6	P28482	MAPK1	S884	K878N	878	Missense	distal	-6	no	14.794	14.786	PhosphoSitePlus	TCGA;ICGC;COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q14686	NCOA6	P28482	MAPK1	T932	P937S	937	Missense	distal	5	no	14.252	14.270	EPSD	TCGA;ICGC;COSMIC;GDSC;CCLE	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q14686	NCOA6	P28482	MAPK1	S1091	P1098S	1098	Missense	distal	7	no	16.186	16.197	EPSD	TCGA;ICGC;COSMIC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q14686	NCOA6	P28482	MAPK1	S1091	A1086V	1086	Missense	distal	-5	no	16.186	16.157	EPSD	TCGA;ICGC;COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q14686	NCOA6	P28482	MAPK1	T1103	P1098S	1098	Missense	distal	-5	no	13.609	13.683	EPSD	TCGA;ICGC;COSMIC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q14686	NCOA6	P28482	MAPK1	T1211	P1209L	1209	Missense	proximal	-2	no	15.809	13.892	EPSD	TCGA;COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q14686	NCOA6	P28482	MAPK1	S1216	P1209L	1209	Missense	distal	-7	no	14.689	14.677	EPSD	TCGA;COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q14686	NCOA6	P28482	MAPK1	T1224	P1229R	1229	Missense	distal	5	no	16.939	16.989	EPSD	TCGA;ICGC;COSMIC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q14686	NCOA6	P28482	MAPK1	S1240	E1242Q	1242	Missense	proximal	2	no	15.213	15.102	EPSD	TCGA;ICGC;COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q14686	NCOA6	P28482	MAPK1	S1240	S1247F	1247	Missense	distal	7	no	15.213	15.560	EPSD	TCGA;ICGC;COSMIC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q14686	NCOA6	P28482	MAPK1	S1240	P1234L	1234	Missense	distal	-6	no	15.213	15.121	EPSD	TCGA;ICGC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q14686	NCOA6	P28482	MAPK1	T1299	T1299A	1299	Missense	central	0	yes	13.686	0.000	EPSD	TCGA;ICGC;COSMIC	8.102	Loss
CMGC_MAPK_ERK1_MAPK1_ST	Q14686	NCOA6	P28482	MAPK1	T1299	P1294S	1294	Missense	distal	-5	no	13.686	13.760	EPSD	TCGA;ICGC;COSMIC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q14686	NCOA6	P28482	MAPK1	S1377	A1382V	1382	Missense	distal	5	no	12.040	12.057	EPSD	TCGA;ICGC;COSMIC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q14686	NCOA6	P28482	MAPK1	S1377	P1380S	1380	Missense	distal	3	no	12.040	12.109	EPSD	TCGA;ICGC;COSMIC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q14686	NCOA6	P28482	MAPK1	T1379	A1382V	1382	Missense	distal	3	no	12.352	12.332	EPSD	TCGA;ICGC;COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q14686	NCOA6	P28482	MAPK1	T1379	P1380S	1380	Missense	proximal	1	no	12.352	2.958	EPSD	TCGA;ICGC;COSMIC	8.102	Loss
CMGC_MAPK_ERK1_MAPK1_ST	Q14686	NCOA6	P28482	MAPK1	T1379	P1385L	1385	Missense	distal	6	no	12.352	11.946	EPSD	TCGA;ICGC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q14686	NCOA6	P28482	MAPK1	S1481	E1486Q	1486	Missense	distal	5	no	15.799	15.704	EPSD	TCGA;ICGC;COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q14686	NCOA6	P28482	MAPK1	T1516	V1520D	1520	Missense	distal	4	no	12.348	12.351	EPSD	TCGA;ICGC;COSMIC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q14686	NCOA6	P28482	MAPK1	S1721	A1717T	1717	Missense	distal	-4	no	12.747	12.727	EPSD	TCGA;ICGC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q14686	NCOA6	P28482	MAPK1	S1721	A1723P	1723	Missense	proximal	2	no	12.747	12.877	EPSD	TCGA;ICGC;COSMIC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q14686	NCOA6	P28482	MAPK1	T1739	S1745F	1745	Missense	distal	6	no	14.570	14.130	EPSD	TCGA;ICGC;COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q14686	NCOA6	P28482	MAPK1	T1739	P1740S	1740	Missense	proximal	1	no	14.570	5.175	EPSD	TCGA;ICGC;COSMIC	8.102	Loss
CMGC_MAPK_ERK1_MAPK1_ST	Q14686	NCOA6	P28482	MAPK1	T1739	P1744S	1744	Missense	distal	5	no	14.570	14.588	EPSD	TCGA;ICGC;COSMIC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q14686	NCOA6	P28482	MAPK1	S1745	S1745F	1745	Missense	central	0	yes	14.267	0.000	EPSD	TCGA;ICGC;COSMIC	8.102	Loss
CMGC_MAPK_ERK1_MAPK1_ST	Q14686	NCOA6	P28482	MAPK1	S1745	P1747L	1747	Missense	proximal	2	no	14.267	14.119	EPSD	TCGA;ICGC;COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q14686	NCOA6	P28482	MAPK1	S1745	P1747S	1747	Missense	proximal	2	no	14.267	14.239	EPSD	TCGA;ICGC;COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q14686	NCOA6	P28482	MAPK1	S1745	P1740S	1740	Missense	distal	-5	no	14.267	14.341	EPSD	TCGA;ICGC;COSMIC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q14686	NCOA6	P28482	MAPK1	S1745	P1744S	1744	Missense	proximal	-1	no	14.267	14.223	EPSD	TCGA;ICGC;COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q14686	NCOA6	P28482	MAPK1	S1751	S1756Y	1756	Missense	distal	5	no	13.564	13.275	EPSD	TCGA;COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q14686	NCOA6	P28482	MAPK1	S1751	S1745F	1745	Missense	distal	-6	no	13.564	13.480	EPSD	TCGA;ICGC;COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q14686	NCOA6	P28482	MAPK1	S1751	P1747L	1747	Missense	distal	-4	no	13.564	13.260	EPSD	TCGA;ICGC;COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q14686	NCOA6	P28482	MAPK1	S1751	P1755S	1755	Missense	distal	4	no	13.564	13.553	EPSD	TCGA;ICGC;COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q14686	NCOA6	P28482	MAPK1	S1751	P1747S	1747	Missense	distal	-4	no	13.564	13.480	EPSD	TCGA;ICGC;COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q14686	NCOA6	P28482	MAPK1	S1751	P1744S	1744	Missense	distal	-7	no	13.564	13.560	EPSD	TCGA;ICGC;COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q14686	NCOA6	P28482	MAPK1	S1756	S1756Y	1756	Missense	central	0	yes	8.234	0.000	EPSD	TCGA;COSMIC	8.102	Loss
CMGC_MAPK_ERK1_MAPK1_ST	Q14686	NCOA6	P28482	MAPK1	S1756	P1755S	1755	Missense	proximal	-1	no	8.234	8.191	EPSD	TCGA;ICGC;COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q14686	NCOA6	P28482	MAPK1	S1794	L1796P	1796	Missense	proximal	2	no	12.374	12.522	EPSD	TCGA;ICGC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q14686	NCOA6	P28482	MAPK1	S1800	L1796P	1796	Missense	distal	-4	no	12.806	13.110	EPSD	TCGA;ICGC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q14686	NCOA6	P28482	MAPK1	S1809	R1808Q	1808	Missense	proximal	-1	no	14.569	14.547	EPSD	TCGA;ICGC;COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q14686	NCOA6	P28482	MAPK1	S1809	S1812L	1812	Missense	distal	3	no	14.569	14.589	EPSD	TCGA;ICGC;COSMIC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q14686	NCOA6	P28482	MAPK1	T1898	A1901S	1901	Missense	distal	3	no	9.197	9.188	EPSD	TCGA	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q14686	NCOA6	P28482	MAPK1	T1898	A1901G	1901	Missense	distal	3	no	9.197	9.203	EPSD	TCGA;ICGC;COSMIC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q14686	NCOA6	P28482	MAPK1	S2018	R2019P	2019	Missense	proximal	1	no	2.682	12.336	EPSD	TCGA;ICGC;COSMIC	8.102	Gain
CMGC_MAPK_ERK1_MAPK1_ST	Q9UQC2	GAB2	P28482	MAPK1	S133	S140F	140	Missense	distal	7	no	8.655	9.003	EPSD	TCGA;COSMIC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q9UQC2	GAB2	P28482	MAPK1	S141	S140F	140	Missense	proximal	-1	no	14.587	14.541	EPSD	TCGA;COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q9UQC2	GAB2	P28482	MAPK1	T171	P175H	175	Missense	distal	4	no	9.851	9.676	EPSD	TCGA	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q9UQC2	GAB2	P28482	MAPK1	T265	F261S	261	Missense	distal	-4	no	8.047	8.308	EPSD	TCGA	8.102	Gain
CMGC_MAPK_ERK1_MAPK1_ST	Q9UQC2	GAB2	P28482	MAPK1	S274	R270H	270	Missense	distal	-4	no	8.480	8.328	EPSD	TCGA;COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q9UQC2	GAB2	P28482	MAPK1	S274	G276D	276	Missense	proximal	2	no	8.480	8.446	EPSD	TCGA	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q9UQC2	GAB2	P28482	MAPK1	T294	T294N	294	Missense	central	0	yes	9.420	0.000	EPSD	TCGA;COSMIC	8.102	Loss
CMGC_MAPK_ERK1_MAPK1_ST	Q9UQC2	GAB2	P28482	MAPK1	S368	S368N	368	Missense	central	0	yes	15.866	0.000	EPSD	TCGA;COSMIC	8.102	Loss
CMGC_MAPK_ERK1_MAPK1_ST	Q9UQC2	GAB2	P28482	MAPK1	S381	V382F	382	Missense	proximal	1	no	5.245	8.216	EPSD	TCGA;COSMIC	8.102	Gain
CMGC_MAPK_ERK1_MAPK1_ST	Q9UQC2	GAB2	P28482	MAPK1	S480	I477N	477	Missense	distal	-3	no	18.893	19.174	EPSD	TCGA;COSMIC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q9UQC2	GAB2	P28482	MAPK1	S506	R500Q	500	Missense	distal	-6	no	8.453	8.429	EPSD	TCGA;COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q9UQC2	GAB2	P28482	MAPK1	S506	P502L	502	Missense	distal	-4	no	8.453	8.148	EPSD	TCGA;COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q9UQC2	GAB2	P28482	MAPK1	S543	D537N	537	Missense	distal	-6	no	13.639	13.593	EPSD	TCGA;COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q9UQC2	GAB2	P28482	MAPK1	S623	P621Q	621	Missense	proximal	-2	no	15.505	12.512	PhosphoSitePlus	TCGA;COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q9UQC2	GAB2	P28482	MAPK1	S625	P621Q	621	Missense	distal	-4	no	14.030	13.837	EPSD	TCGA;COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P10828	THRB	P28482	MAPK1	T2	P3L	3	Missense	proximal	1	no	12.046	3.237	EPSD	TCGA;ICGC;COSMIC	8.102	Loss
CMGC_MAPK_ERK1_MAPK1_ST	P10828	THRB	P28482	MAPK1	T2	T7I	7	Missense	distal	5	no	12.046	11.803	EPSD	TCGA;ICGC;COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P10828	THRB	P28482	MAPK1	S55	S55L	55	Missense	central	0	yes	14.655	0.000	EPSD	TCGA;ICGC;COSMIC;GDSC;CCLE	8.102	Loss
CMGC_MAPK_ERK1_MAPK1_ST	P10828	THRB	P28482	MAPK1	S55	P56L	56	Missense	proximal	1	no	14.655	5.845	EPSD	TCGA;ICGC;COSMIC	8.102	Loss
CMGC_MAPK_ERK1_MAPK1_ST	P10828	THRB	P28482	MAPK1	S55	H57Y	57	Missense	proximal	2	no	14.655	14.589	EPSD	TCGA;ICGC;COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P10828	THRB	P28482	MAPK1	S55	E52G	52	Missense	distal	-3	no	14.655	14.646	EPSD	TCGA;ICGC;COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P10828	THRB	P28482	MAPK1	S142	G149E	149	Missense	distal	7	no	8.459	8.331	PhosphoSitePlus	TCGA;ICGC;COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P10828	THRB	P28482	MAPK1	S142	S144F	144	Missense	proximal	2	no	8.459	8.327	PhosphoSitePlus	TCGA;ICGC;COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P10828	THRB	P28482	MAPK1	S142	P141S	141	Missense	proximal	-1	no	8.459	8.416	PhosphoSitePlus	TCGA;ICGC;COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P10828	THRB	P28482	MAPK1	S142	L139I	139	Missense	distal	-3	no	8.459	8.402	PhosphoSitePlus	TCGA;ICGC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P14921	ETS1	P28482	MAPK1	S26	P27S	27	Missense	proximal	1	no	15.770	6.375	EPSD	TCGA;ICGC	8.102	Loss
CMGC_MAPK_ERK1_MAPK1_ST	Q9NRF2	SH2B1	P28482	MAPK1	S88	P94L	94	Missense	distal	6	no	13.850	13.444	EPSD	TCGA;ICGC;COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q9NRF2	SH2B1	P28482	MAPK1	S88	P90T	90	Missense	proximal	2	no	13.850	13.800	EPSD	TCGA;ICGC;COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q9NRF2	SH2B1	P28482	MAPK1	S96	P94L	94	Missense	proximal	-2	no	15.960	14.043	PhosphoSitePlus	TCGA;ICGC;COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q9NRF2	SH2B1	P28482	MAPK1	S96	A99V	99	Missense	distal	3	no	15.960	15.940	PhosphoSitePlus	TCGA;ICGC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q9NRF2	SH2B1	P28482	MAPK1	S96	P90T	90	Missense	distal	-6	no	15.960	15.911	PhosphoSitePlus	TCGA;ICGC;COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q9NRF2	SH2B1	P28482	MAPK1	S96	S102L	102	Missense	distal	6	no	15.960	15.554	PhosphoSitePlus	TCGA;ICGC;COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q9NRF2	SH2B1	P28482	MAPK1	S102	A99V	99	Missense	distal	-3	no	13.059	13.119	EPSD	TCGA;ICGC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q9NRF2	SH2B1	P28482	MAPK1	S102	S102L	102	Missense	central	0	yes	13.059	0.000	EPSD	TCGA;ICGC;COSMIC	8.102	Loss
CMGC_MAPK_ERK1_MAPK1_ST	Q9NRF2	SH2B1	P28482	MAPK1	S136	T143A	143	Missense	distal	7	no	9.648	9.677	EPSD	TCGA;ICGC;COSMIC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q9NRF2	SH2B1	P28482	MAPK1	S139	T143A	143	Missense	distal	4	no	8.285	8.305	EPSD	TCGA;ICGC;COSMIC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q9NRF2	SH2B1	P28482	MAPK1	S219	D216H	216	Missense	distal	-3	no	12.112	11.891	EPSD	TCGA;ICGC;COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q9NRF2	SH2B1	P28482	MAPK1	S384	R386C	386	Missense	proximal	2	no	12.580	12.207	EPSD	TCGA;ICGC;COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P53355	DAPK1	P28482	MAPK1	T180	A185T	185	Missense	distal	5	no	11.610	11.696	EPSD	TCGA;ICGC;COSMIC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P53355	DAPK1	P28482	MAPK1	T180	T180I	180	Missense	central	0	yes	11.610	0.000	EPSD	TCGA;ICGC;COSMIC	8.102	Loss
CMGC_MAPK_ERK1_MAPK1_ST	P53355	DAPK1	P28482	MAPK1	S321	M328V	328	Missense	distal	7	no	8.189	8.113	EPSD	TCGA;ICGC;COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P53355	DAPK1	P28482	MAPK1	S321	R317I	317	Missense	distal	-4	no	8.189	7.608	EPSD	TCGA;ICGC;COSMIC	8.102	Loss
CMGC_MAPK_ERK1_MAPK1_ST	P53355	DAPK1	P28482	MAPK1	S333	M328V	328	Missense	distal	-5	no	8.356	8.300	EPSD	TCGA;ICGC;COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P53355	DAPK1	P28482	MAPK1	S342	A347S	347	Missense	distal	5	no	9.126	9.286	EPSD	TCGA;ICGC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P53355	DAPK1	P28482	MAPK1	T612	G610R	610	Missense	proximal	-2	no	13.055	14.431	EPSD	TCGA;ICGC;COSMIC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P53355	DAPK1	P28482	MAPK1	S734	P733H	733	Missense	proximal	-1	no	19.425	19.382	PhosphoSitePlus	TCGA	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P53355	DAPK1	P28482	MAPK1	S734	P735L	735	Missense	proximal	1	no	19.425	10.615	PhosphoSitePlus	TCGA;ICGC;COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P53355	DAPK1	P28482	MAPK1	T1053	V1051M	1051	Missense	proximal	-2	no	13.831	11.690	EPSD	TCGA;ICGC;COSMIC;GDSC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P41182	BCL6	P28482	MAPK1	S250	R244L	244	Missense	distal	-6	no	15.929	15.829	EPSD	TCGA;ICGC;COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P41182	BCL6	P28482	MAPK1	S260	P261R	261	Missense	proximal	1	no	15.090	5.435	EPSD	TCGA;ICGC;COSMIC	8.102	Loss
CMGC_MAPK_ERK1_MAPK1_ST	P41182	BCL6	P28482	MAPK1	S260	I265N	265	Missense	distal	5	no	15.090	15.334	EPSD	TCGA;ICGC;COSMIC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P41182	BCL6	P28482	MAPK1	S330	K326N	326	Missense	distal	-4	no	14.464	14.433	EPSD	TCGA;ICGC;COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P41182	BCL6	P28482	MAPK1	S343	S349N	349	Missense	distal	6	no	17.275	17.179	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P41182	BCL6	P28482	MAPK1	S343	E346K	346	Missense	distal	3	no	17.275	17.282	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P41182	BCL6	P28482	MAPK1	S361	A364V	364	Missense	distal	3	no	13.020	12.999	EPSD	TCGA;ICGC;COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P41182	BCL6	P28482	MAPK1	S361	K365N	365	Missense	distal	4	no	13.020	12.995	EPSD	TCGA;ICGC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P41182	BCL6	P28482	MAPK1	S361	P367L	367	Missense	distal	6	no	13.020	12.613	EPSD	TCGA;ICGC;COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P41182	BCL6	P28482	MAPK1	S366	A364V	364	Missense	proximal	-2	no	13.294	14.568	EPSD	TCGA;ICGC;COSMIC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P41182	BCL6	P28482	MAPK1	S366	K365N	365	Missense	proximal	-1	no	13.294	13.286	EPSD	TCGA;ICGC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P41182	BCL6	P28482	MAPK1	S366	P367L	367	Missense	proximal	1	no	13.294	4.484	EPSD	TCGA;ICGC;COSMIC	8.102	Loss
CMGC_MAPK_ERK1_MAPK1_ST	P41182	BCL6	P28482	MAPK1	S404	R406Q	406	Missense	proximal	2	no	13.330	13.038	EPSD	TCGA;ICGC;COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P41182	BCL6	P28482	MAPK1	S404	P405L	405	Missense	proximal	1	no	13.330	4.520	EPSD	TCGA;ICGC;COSMIC	8.102	Loss
CMGC_MAPK_ERK1_MAPK1_ST	P41182	BCL6	P28482	MAPK1	S427	L425R	425	Missense	proximal	-2	no	13.658	13.756	EPSD	TCGA;ICGC;COSMIC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P41182	BCL6	P28482	MAPK1	S427	A433V	433	Missense	distal	6	no	13.658	13.739	EPSD	TCGA;ICGC;COSMIC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P41182	BCL6	P28482	MAPK1	S427	T429I	429	Missense	proximal	2	no	13.658	13.537	EPSD	TCGA;ICGC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P41182	BCL6	P28482	MAPK1	S427	L425I	425	Missense	proximal	-2	no	13.658	13.680	EPSD	TCGA;ICGC;COSMIC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P41182	BCL6	P28482	MAPK1	S457	R452M	452	Missense	distal	-5	no	13.867	13.972	EPSD	TCGA;ICGC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P41182	BCL6	P28482	MAPK1	S457	R459H	459	Missense	proximal	2	no	13.867	13.624	EPSD	TCGA;ICGC;COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P41182	BCL6	P28482	MAPK1	S466	M470I	470	Missense	distal	4	no	11.972	11.994	EPSD	TCGA;ICGC;COSMIC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P41182	BCL6	P28482	MAPK1	S466	R459H	459	Missense	distal	-7	no	11.972	11.961	EPSD	TCGA;ICGC;COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q13164	MAPK7	P28482	MAPK1	S210	P211S	211	Missense	proximal	1	no	10.837	1.442	EPSD	TCGA;ICGC;COSMIC	8.102	Loss
CMGC_MAPK_ERK1_MAPK1_ST	Q13164	MAPK7	P28482	MAPK1	S282	A288D	288	Missense	distal	6	no	14.633	14.884	EPSD	TCGA;ICGC;COSMIC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q13164	MAPK7	P28482	MAPK1	S421	A424S	424	Missense	distal	3	no	13.740	13.731	EPSD	TCGA;ICGC;COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q13164	MAPK7	P28482	MAPK1	S421	P420S	420	Missense	proximal	-1	no	13.740	13.697	EPSD	TCGA;ICGC;COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q13164	MAPK7	P28482	MAPK1	S433	A430V	430	Missense	distal	-3	no	11.860	11.920	EPSD	TCGA;ICGC;COSMIC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q13164	MAPK7	P28482	MAPK1	T594	P589R	589	Missense	distal	-5	no	14.134	14.181	EPSD	TCGA;ICGC;COSMIC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q13164	MAPK7	P28482	MAPK1	S707	V710A	710	Missense	distal	3	no	13.239	13.260	EPSD	TCGA;ICGC;COSMIC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q13164	MAPK7	P28482	MAPK1	T733	G738E	738	Missense	distal	5	no	12.957	12.932	PhosphoSitePlus	TCGA;ICGC;COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q01844	EWSR1	P28482	MAPK1	T79	T79I	79	Missense	central	0	yes	12.809	0.000	PhosphoSitePlus	TCGA;ICGC;COSMIC	8.102	Loss
CMGC_MAPK_ERK1_MAPK1_ST	Q9H9Z2	LIN28A	P28482	MAPK1	T189	R192Q	192	Missense	distal	3	no	12.220	12.242	EPSD	TCGA;ICGC;GDSC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q9H9Z2	LIN28A	P28482	MAPK1	T189	P188Q	188	Missense	proximal	-1	no	12.220	12.179	EPSD	TCGA;ICGC;COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q9H9Z2	LIN28A	P28482	MAPK1	T189	G186E	186	Missense	distal	-3	no	12.220	12.229	EPSD	TCGA;ICGC;COSMIC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q12772	SREBF2	P28482	MAPK1	S101	A104V	104	Missense	distal	3	no	13.077	13.056	EPSD	TCGA;ICGC;COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q12772	SREBF2	P28482	MAPK1	S106	A104V	104	Missense	proximal	-2	no	13.276	14.550	EPSD	TCGA;ICGC;COSMIC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q12772	SREBF2	P28482	MAPK1	S117	P122S	122	Missense	distal	5	no	14.074	14.092	EPSD	TCGA;ICGC;COSMIC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q12772	SREBF2	P28482	MAPK1	S117	P118L	118	Missense	proximal	1	no	14.074	5.264	EPSD	TCGA;ICGC	8.102	Loss
CMGC_MAPK_ERK1_MAPK1_ST	Q12772	SREBF2	P28482	MAPK1	T124	P122S	122	Missense	proximal	-2	no	15.491	12.657	EPSD	TCGA;ICGC;COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q12772	SREBF2	P28482	MAPK1	T124	P118L	118	Missense	distal	-6	no	15.491	15.400	EPSD	TCGA;ICGC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q12772	SREBF2	P28482	MAPK1	T128	R134H	134	Missense	distal	6	no	13.670	13.471	EPSD	TCGA;ICGC;COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q12772	SREBF2	P28482	MAPK1	T128	P122S	122	Missense	distal	-6	no	13.670	13.644	EPSD	TCGA;ICGC;COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q12772	SREBF2	P28482	MAPK1	T128	P135L	135	Missense	distal	7	no	13.670	13.969	EPSD	TCGA;ICGC;COSMIC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q12772	SREBF2	P28482	MAPK1	T334	R341Q	341	Missense	distal	7	no	8.067	8.182	EPSD	TCGA;ICGC;COSMIC	8.102	Gain
CMGC_MAPK_ERK1_MAPK1_ST	Q12772	SREBF2	P28482	MAPK1	T334	E339D	339	Missense	distal	5	no	8.067	8.136	EPSD	TCGA;ICGC;COSMIC	8.102	Gain
CMGC_MAPK_ERK1_MAPK1_ST	Q12772	SREBF2	P28482	MAPK1	S432	N427S	427	Missense	distal	-5	no	15.410	15.458	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q12772	SREBF2	P28482	MAPK1	S455	L457V	457	Missense	proximal	2	no	18.586	18.680	PhosphoSitePlus;EPSD	TCGA;ICGC;COSMIC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q12772	SREBF2	P28482	MAPK1	S469	A473V	473	Missense	distal	4	no	17.557	17.551	EPSD	TCGA;ICGC;COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q12772	SREBF2	P28482	MAPK1	S855	M854I	854	Missense	proximal	-1	no	14.412	14.396	EPSD	TCGA;ICGC;COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q12772	SREBF2	P28482	MAPK1	S859	M854I	854	Missense	distal	-5	no	8.112	8.169	EPSD	TCGA;ICGC;COSMIC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q12772	SREBF2	P28482	MAPK1	S859	V863M	863	Missense	distal	4	no	8.112	8.024	EPSD	TCGA;ICGC;COSMIC	8.102	Loss
CMGC_MAPK_ERK1_MAPK1_ST	Q12772	SREBF2	P28482	MAPK1	S914	P915L	915	Missense	proximal	1	no	11.735	2.925	EPSD	TCGA;ICGC;COSMIC	8.102	Loss
CMGC_MAPK_ERK1_MAPK1_ST	Q12772	SREBF2	P28482	MAPK1	S1046	A1045D	1045	Missense	proximal	-1	no	13.616	13.597	EPSD	TCGA;ICGC;COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q12772	SREBF2	P28482	MAPK1	S1094	R1089H	1089	Missense	distal	-5	no	8.783	8.860	EPSD	TCGA;ICGC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q12772	SREBF2	P28482	MAPK1	S1094	R1089C	1089	Missense	distal	-5	no	8.783	9.013	EPSD	TCGA;ICGC;COSMIC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q12772	SREBF2	P28482	MAPK1	S1098	R1102W	1102	Missense	distal	4	no	13.683	13.400	EPSD	TCGA;ICGC;COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P06401	PGR	P28482	MAPK1	S20	S25F	25	Missense	distal	5	no	16.972	16.775	EPSD	TCGA;ICGC;COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P06401	PGR	P28482	MAPK1	S20	S20F	20	Missense	central	0	yes	16.972	0.000	EPSD	TCGA;ICGC;COSMIC	8.102	Loss
CMGC_MAPK_ERK1_MAPK1_ST	P06401	PGR	P28482	MAPK1	S20	L27P	27	Missense	distal	7	no	16.972	16.673	EPSD	TCGA;ICGC;COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P06401	PGR	P28482	MAPK1	S25	S25F	25	Missense	central	0	yes	17.333	0.000	EPSD	TCGA;ICGC;COSMIC	8.102	Loss
CMGC_MAPK_ERK1_MAPK1_ST	P06401	PGR	P28482	MAPK1	S25	S20F	20	Missense	distal	-5	no	17.333	17.421	EPSD	TCGA;ICGC;COSMIC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P06401	PGR	P28482	MAPK1	S25	L27P	27	Missense	proximal	2	no	17.333	17.481	EPSD	TCGA;ICGC;COSMIC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P06401	PGR	P28482	MAPK1	S102	G109R	109	Missense	distal	7	no	14.000	13.935	EPSD	TCGA;ICGC;COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P06401	PGR	P28482	MAPK1	S102	S102I	102	Missense	central	0	yes	14.000	0.000	EPSD	TCGA;ICGC	8.102	Loss
CMGC_MAPK_ERK1_MAPK1_ST	P06401	PGR	P28482	MAPK1	S102	S101C	101	Missense	proximal	-1	no	14.000	13.922	EPSD	TCGA;ICGC;COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P06401	PGR	P28482	MAPK1	S102	S108I	108	Missense	distal	6	no	14.000	13.333	EPSD	TCGA;ICGC;COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P06401	PGR	P28482	MAPK1	S130	P132S	132	Missense	proximal	2	no	13.049	13.021	EPSD	TCGA;ICGC;COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P06401	PGR	P28482	MAPK1	S190	L197F	197	Missense	distal	7	no	13.636	13.695	EPSD	TCGA;ICGC;COSMIC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P06401	PGR	P28482	MAPK1	S213	A218V	218	Missense	distal	5	no	15.143	15.160	EPSD	TCGA;ICGC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P06401	PGR	P28482	MAPK1	S294	T299A	299	Missense	distal	5	no	14.860	14.774	PhosphoSitePlus	TCGA;ICGC;COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P06401	PGR	P28482	MAPK1	S294	A287E	287	Missense	distal	-7	no	14.860	14.867	PhosphoSitePlus	TCGA;ICGC;COSMIC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P06401	PGR	P28482	MAPK1	S294	R293C	293	Missense	proximal	-1	no	14.860	14.757	PhosphoSitePlus	TCGA;ICGC;COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P06401	PGR	P28482	MAPK1	S344	F339Y	339	Missense	distal	-5	no	9.114	9.157	EPSD	TCGA;ICGC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P06401	PGR	P28482	MAPK1	S345	F339Y	339	Missense	distal	-6	no	15.210	15.180	EPSD	TCGA;ICGC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P06401	PGR	P28482	MAPK1	T351	A354T	354	Missense	distal	3	no	13.423	13.406	EPSD	TCGA;ICGC;COSMIC;GDSC;CCLE	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P06401	PGR	P28482	MAPK1	S400	A394V	394	Missense	distal	-6	no	13.209	13.162	EPSD	TCGA;ICGC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P06401	PGR	P28482	MAPK1	S549	Q556H	556	Missense	distal	7	no	10.684	10.787	EPSD	TCGA;ICGC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P06401	PGR	P28482	MAPK1	S549	S552N	552	Missense	distal	3	no	10.684	10.606	EPSD	TCGA;ICGC;COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P06401	PGR	P28482	MAPK1	S554	Q556H	556	Missense	proximal	2	no	12.386	12.434	EPSD	TCGA;ICGC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P06401	PGR	P28482	MAPK1	S554	S552N	552	Missense	proximal	-2	no	12.386	12.400	EPSD	TCGA;ICGC;COSMIC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P06401	PGR	P28482	MAPK1	S676	Q679E	679	Missense	distal	3	no	14.149	14.072	EPSD	TCGA;ICGC;COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P06401	PGR	P28482	MAPK1	S676	L683F	683	Missense	distal	7	no	14.149	14.208	EPSD	TCGA;ICGC;COSMIC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P06401	PGR	P28482	MAPK1	S676	R672T	672	Missense	distal	-4	no	14.149	13.925	EPSD	TCGA;ICGC;COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P06401	PGR	P28482	MAPK1	S676	S676L	676	Missense	central	0	yes	14.149	0.000	EPSD	TCGA;ICGC;COSMIC	8.102	Loss
CMGC_MAPK_ERK1_MAPK1_ST	P06401	PGR	P28482	MAPK1	S676	Q679L	679	Missense	distal	3	no	14.149	14.171	EPSD	TCGA	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P06401	PGR	P28482	MAPK1	S676	R672I	672	Missense	distal	-4	no	14.149	13.568	EPSD	TCGA;ICGC;COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P06401	PGR	P28482	MAPK1	S676	P677T	677	Missense	proximal	1	no	14.149	5.650	EPSD	TCGA;ICGC;COSMIC	8.102	Loss
CMGC_MAPK_ERK1_MAPK1_ST	P46695	IER3	P28482	MAPK1	T123	A118T	118	Missense	distal	-5	no	14.252	14.230	EPSD	TCGA	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q15596	NCOA2	P28482	MAPK1	S29	G27E	27	Missense	proximal	-2	no	14.576	15.390	EPSD	TCGA;ICGC;COSMIC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q15596	NCOA2	P28482	MAPK1	S29	G27R	27	Missense	proximal	-2	no	14.576	15.951	EPSD	TCGA;ICGC;COSMIC;GDSC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q15596	NCOA2	P28482	MAPK1	S29	P23S	23	Missense	distal	-6	no	14.576	14.550	EPSD	TCGA;ICGC;COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q15596	NCOA2	P28482	MAPK1	S267	S266L	266	Missense	proximal	-1	no	8.540	8.524	EPSD	TCGA;ICGC;COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q15596	NCOA2	P28482	MAPK1	S267	L264I	264	Missense	distal	-3	no	8.540	8.483	EPSD	TCGA;ICGC;COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q15596	NCOA2	P28482	MAPK1	S267	S269N	269	Missense	proximal	2	no	8.540	8.492	EPSD	TCGA;ICGC;COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q15596	NCOA2	P28482	MAPK1	S267	R261S	261	Missense	distal	-6	no	8.540	8.506	EPSD	TCGA;ICGC;COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q15596	NCOA2	P28482	MAPK1	S269	S266L	266	Missense	distal	-3	no	9.425	9.218	EPSD	TCGA;ICGC;COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q15596	NCOA2	P28482	MAPK1	S269	L276F	276	Missense	distal	7	no	9.425	9.484	EPSD	TCGA;ICGC;COSMIC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q15596	NCOA2	P28482	MAPK1	S269	L264I	264	Missense	distal	-5	no	9.425	9.485	EPSD	TCGA;ICGC;COSMIC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q15596	NCOA2	P28482	MAPK1	S269	S269N	269	Missense	central	0	yes	9.425	0.000	EPSD	TCGA;ICGC;COSMIC	8.102	Loss
CMGC_MAPK_ERK1_MAPK1_ST	Q15596	NCOA2	P28482	MAPK1	S402	Q406K	406	Missense	distal	4	no	13.635	13.720	EPSD	TCGA;ICGC;COSMIC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q15596	NCOA2	P28482	MAPK1	S402	S399R	399	Missense	distal	-3	no	13.635	13.792	EPSD	TCGA;ICGC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q15596	NCOA2	P28482	MAPK1	S487	R491H	491	Missense	distal	4	no	11.426	11.285	EPSD	TCGA;ICGC;COSMIC;GDSC;CCLE	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q15596	NCOA2	P28482	MAPK1	S493	R491H	491	Missense	proximal	-2	no	15.547	14.610	EPSD	TCGA;ICGC;COSMIC;GDSC;CCLE	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q15596	NCOA2	P28482	MAPK1	S554	K558T	558	Missense	distal	4	no	14.431	14.331	EPSD	TCGA;ICGC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q15596	NCOA2	P28482	MAPK1	S565	S565F	565	Missense	central	0	yes	14.944	0.000	EPSD	TCGA;ICGC;COSMIC	8.102	Loss
CMGC_MAPK_ERK1_MAPK1_ST	Q15596	NCOA2	P28482	MAPK1	S565	M569V	569	Missense	distal	4	no	14.944	15.033	EPSD	TCGA;ICGC;COSMIC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q15596	NCOA2	P28482	MAPK1	S565	P566L	566	Missense	proximal	1	no	14.944	6.135	EPSD	TCGA;ICGC;COSMIC	8.102	Loss
CMGC_MAPK_ERK1_MAPK1_ST	Q15596	NCOA2	P28482	MAPK1	S565	K558T	558	Missense	distal	-7	no	14.944	14.929	EPSD	TCGA;ICGC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q15596	NCOA2	P28482	MAPK1	S655	S655L	655	Missense	central	0	yes	12.120	0.000	EPSD	TCGA;ICGC;COSMIC	8.102	Loss
CMGC_MAPK_ERK1_MAPK1_ST	Q15596	NCOA2	P28482	MAPK1	S655	M652L	652	Missense	distal	-3	no	12.120	12.174	EPSD	TCGA;ICGC;COSMIC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q15596	NCOA2	P28482	MAPK1	S655	P654A	654	Missense	proximal	-1	no	12.120	12.083	EPSD	TCGA;ICGC;COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q15596	NCOA2	P28482	MAPK1	S699	D702Y	702	Missense	distal	3	no	11.988	12.029	EPSD	TCGA;ICGC;COSMIC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q15596	NCOA2	P28482	MAPK1	S699	S699F	699	Missense	central	0	yes	11.988	0.000	EPSD	TCGA;ICGC	8.102	Loss
CMGC_MAPK_ERK1_MAPK1_ST	Q15596	NCOA2	P28482	MAPK1	S736	T729A	729	Missense	distal	-7	no	16.880	16.895	PhosphoSitePlus	TCGA;ICGC;COSMIC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q15596	NCOA2	P28482	MAPK1	T763	P760T	760	Missense	distal	-3	no	14.681	14.471	EPSD	TCGA;ICGC;COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q15596	NCOA2	P28482	MAPK1	S851	A848T	848	Missense	distal	-3	no	14.974	15.131	EPSD	TCGA;ICGC;COSMIC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q15596	NCOA2	P28482	MAPK1	T854	A848T	848	Missense	distal	-6	no	17.168	17.157	EPSD	TCGA;ICGC;COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q15596	NCOA2	P28482	MAPK1	S895	T897N	897	Missense	proximal	2	no	17.270	17.244	EPSD	TCGA;ICGC;COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q15596	NCOA2	P28482	MAPK1	S895	A899D	899	Missense	distal	4	no	17.270	17.266	EPSD	TCGA;ICGC;COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q15596	NCOA2	P28482	MAPK1	S994	T1001M	1001	Missense	distal	7	no	7.900	8.108	EPSD	TCGA;ICGC;COSMIC	8.102	Gain
CMGC_MAPK_ERK1_MAPK1_ST	Q15596	NCOA2	P28482	MAPK1	S1059	G1057D	1057	Missense	proximal	-2	no	11.342	11.234	EPSD	TCGA;ICGC;COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q15596	NCOA2	P28482	MAPK1	S1072	P1068L	1068	Missense	distal	-4	no	14.422	14.118	EPSD	TCGA;ICGC;COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q15596	NCOA2	P28482	MAPK1	S1072	A1070S	1070	Missense	proximal	-2	no	14.422	14.735	EPSD	TCGA;ICGC;COSMIC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q15596	NCOA2	P28482	MAPK1	S1072	A1069V	1069	Missense	distal	-3	no	14.422	14.482	EPSD	TCGA;ICGC;COSMIC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q15596	NCOA2	P28482	MAPK1	T1273	M1272T	1272	Missense	proximal	-1	no	12.258	12.266	EPSD	TCGA;ICGC;COSMIC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P05198	EIF2S1	P28482	MAPK1	S52	M45I	45	Missense	distal	-7	no	8.103	8.092	PhosphoSitePlus	TCGA;ICGC;COSMIC	8.102	Loss
CMGC_MAPK_ERK1_MAPK1_ST	P05198	EIF2S1	P28482	MAPK1	S52	R57C	57	Missense	distal	5	no	8.103	7.671	PhosphoSitePlus	TCGA;ICGC;COSMIC	8.102	Loss
CMGC_MAPK_ERK1_MAPK1_ST	P05198	EIF2S1	P28482	MAPK1	S91	L85V	85	Missense	distal	-6	no	17.128	17.134	EPSD	TCGA;ICGC;COSMIC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P05198	EIF2S1	P28482	MAPK1	T185	R192Q	192	Missense	distal	7	no	12.946	13.062	EPSD	TCGA;ICGC;COSMIC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P05198	EIF2S1	P28482	MAPK1	T185	L184F	184	Missense	proximal	-1	no	12.946	12.917	EPSD	TCGA;ICGC;COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	O60504	SORBS3	P28482	MAPK1	S28	V35L	35	Missense	distal	7	no	8.365	8.371	EPSD	TCGA;ICGC;COSMIC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	O60504	SORBS3	P28482	MAPK1	S97	I94N	94	Missense	distal	-3	no	7.880	8.160	EPSD	TCGA;ICGC;COSMIC	8.102	Gain
CMGC_MAPK_ERK1_MAPK1_ST	O60504	SORBS3	P28482	MAPK1	T191	H185R	185	Missense	distal	-6	no	8.558	8.640	EPSD	TCGA;ICGC;COSMIC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	O60504	SORBS3	P28482	MAPK1	S339	D345N	345	Missense	distal	6	no	13.401	13.350	EPSD	TCGA;ICGC;COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	O60504	SORBS3	P28482	MAPK1	S339	A335S	335	Missense	distal	-4	no	13.401	13.610	EPSD	TCGA;ICGC;COSMIC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	O60504	SORBS3	P28482	MAPK1	S348	D345N	345	Missense	distal	-3	no	12.996	12.964	EPSD	TCGA;ICGC;COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	O60504	SORBS3	P28482	MAPK1	S348	R353W	353	Missense	distal	5	no	12.996	12.467	EPSD	TCGA;ICGC;COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	O60504	SORBS3	P28482	MAPK1	S373	K380N	380	Missense	distal	7	no	13.044	13.078	EPSD	TCGA;ICGC;COSMIC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	O60504	SORBS3	P28482	MAPK1	S508	Y509F	509	Missense	proximal	1	no	9.493	9.933	EPSD	TCGA;ICGC;COSMIC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	O60504	SORBS3	P28482	MAPK1	S508	R501C	501	Missense	distal	-7	no	9.493	9.461	EPSD	TCGA;COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	O60504	SORBS3	P28482	MAPK1	S530	P531S	531	Missense	proximal	1	no	16.487	7.092	EPSD	TCGA;COSMIC	8.102	Loss
CMGC_MAPK_ERK1_MAPK1_ST	O60504	SORBS3	P28482	MAPK1	S530	G524S	524	Missense	distal	-6	no	16.487	16.504	EPSD	TCGA;COSMIC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	O60504	SORBS3	P28482	MAPK1	S545	P546L	546	Missense	proximal	1	no	16.974	8.164	EPSD	TCGA;ICGC;COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	O60504	SORBS3	P28482	MAPK1	S545	R538C	538	Missense	distal	-7	no	16.974	16.942	EPSD	TCGA;COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	O60504	SORBS3	P28482	MAPK1	S551	P546L	546	Missense	distal	-5	no	15.122	15.270	EPSD	TCGA;ICGC;COSMIC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	O60504	SORBS3	P28482	MAPK1	S551	D557N	557	Missense	distal	6	no	15.122	15.071	EPSD	TCGA;ICGC;COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	O60504	SORBS3	P28482	MAPK1	S563	R565C	565	Missense	proximal	2	no	12.854	12.481	EPSD	TCGA;ICGC;COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	O60504	SORBS3	P28482	MAPK1	S563	T567A	567	Missense	distal	4	no	12.854	12.874	EPSD	TCGA;ICGC;COSMIC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	O60504	SORBS3	P28482	MAPK1	S563	D557N	557	Missense	distal	-6	no	12.854	12.808	EPSD	TCGA;ICGC;COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	O60504	SORBS3	P28482	MAPK1	S563	R566H	566	Missense	distal	3	no	12.854	12.897	EPSD	TCGA;ICGC;COSMIC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	O60504	SORBS3	P28482	MAPK1	T585	P586S	586	Missense	proximal	1	no	14.541	5.146	EPSD	TCGA;ICGC;COSMIC	8.102	Loss
CMGC_MAPK_ERK1_MAPK1_ST	O60504	SORBS3	P28482	MAPK1	S606	I612M	612	Missense	distal	6	no	14.445	14.678	EPSD	TCGA;ICGC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	O60504	SORBS3	P28482	MAPK1	T615	I612M	612	Missense	distal	-3	no	13.835	13.839	EPSD	TCGA;ICGC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q13480	GAB1	P28482	MAPK1	S244	M240I	240	Missense	distal	-4	no	13.472	13.267	EPSD	TCGA;ICGC;COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q13480	GAB1	P28482	MAPK1	S244	R248C	248	Missense	distal	4	no	13.472	13.213	EPSD	TCGA;ICGC;COSMIC;CCLE	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q13480	GAB1	P28482	MAPK1	S244	Q238H	238	Missense	distal	-6	no	13.472	13.412	EPSD	TCGA;ICGC;COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q13480	GAB1	P28482	MAPK1	S264	L261R	261	Missense	distal	-3	no	8.666	9.030	EPSD	TCGA;ICGC;COSMIC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q13480	GAB1	P28482	MAPK1	T289	T289N	289	Missense	central	0	yes	16.048	0.000	EPSD	TCGA;ICGC;COSMIC	8.102	Loss
CMGC_MAPK_ERK1_MAPK1_ST	Q13480	GAB1	P28482	MAPK1	T312	Q318E	318	Missense	distal	6	no	17.126	17.447	EPSD	TCGA;ICGC;COSMIC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q13480	GAB1	P28482	MAPK1	T312	Y317C	317	Missense	distal	5	no	17.126	17.014	EPSD	TCGA;ICGC;COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q13480	GAB1	P28482	MAPK1	T312	P310S	310	Missense	proximal	-2	no	17.126	14.291	EPSD	TCGA;ICGC;COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q13480	GAB1	P28482	MAPK1	S355	P356S	356	Missense	proximal	1	no	15.003	5.608	EPSD	TCGA;ICGC;COSMIC	8.102	Loss
CMGC_MAPK_ERK1_MAPK1_ST	Q13480	GAB1	P28482	MAPK1	S355	R354Q	354	Missense	proximal	-1	no	15.003	14.981	EPSD	TCGA;ICGC;COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q13480	GAB1	P28482	MAPK1	S355	T359M	359	Missense	distal	4	no	15.003	14.928	EPSD	TCGA;ICGC;COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q13480	GAB1	P28482	MAPK1	T365	D370N	370	Missense	distal	5	no	9.723	9.625	EPSD	TCGA;ICGC;COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q13480	GAB1	P28482	MAPK1	T365	S367L	367	Missense	proximal	2	no	9.723	9.603	EPSD	TCGA;ICGC;COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q13480	GAB1	P28482	MAPK1	T365	T359M	359	Missense	distal	-6	no	9.723	9.689	EPSD	TCGA;ICGC;COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q13480	GAB1	P28482	MAPK1	S367	D370N	370	Missense	distal	3	no	8.625	8.530	EPSD	TCGA;ICGC;COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q13480	GAB1	P28482	MAPK1	S367	S367L	367	Missense	central	0	yes	8.625	0.000	EPSD	TCGA;ICGC;COSMIC	8.102	Loss
CMGC_MAPK_ERK1_MAPK1_ST	Q13480	GAB1	P28482	MAPK1	T377	R384C	384	Missense	distal	7	no	7.595	8.251	EPSD	TCGA;ICGC;COSMIC	8.102	Gain
CMGC_MAPK_ERK1_MAPK1_ST	Q13480	GAB1	P28482	MAPK1	S381	P382S	382	Missense	proximal	1	no	15.553	6.158	EPSD	TCGA;ICGC;COSMIC	8.102	Loss
CMGC_MAPK_ERK1_MAPK1_ST	Q13480	GAB1	P28482	MAPK1	S381	R384C	384	Missense	distal	3	no	15.553	15.679	EPSD	TCGA;ICGC;COSMIC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q13480	GAB1	P28482	MAPK1	S381	R384H	384	Missense	distal	3	no	15.553	15.596	EPSD	TCGA;ICGC;COSMIC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q13480	GAB1	P28482	MAPK1	S454	P452L	452	Missense	proximal	-2	no	16.090	14.173	EPSD	TCGA;ICGC;COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q13480	GAB1	P28482	MAPK1	S454	M450K	450	Missense	distal	-4	no	16.090	16.545	EPSD	TCGA;ICGC;COSMIC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q13480	GAB1	P28482	MAPK1	S454	R457Q	457	Missense	distal	3	no	16.090	16.112	EPSD	TCGA;ICGC;GDSC;CCLE	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q13480	GAB1	P28482	MAPK1	S454	S460F	460	Missense	distal	6	no	16.090	15.649	EPSD	TCGA;ICGC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q13480	GAB1	P28482	MAPK1	S462	R457Q	457	Missense	distal	-5	no	8.166	8.243	EPSD	TCGA;ICGC;GDSC;CCLE	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q13480	GAB1	P28482	MAPK1	S462	S460F	460	Missense	proximal	-2	no	8.166	8.359	EPSD	TCGA;ICGC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q13480	GAB1	P28482	MAPK1	S500	R507M	507	Missense	distal	7	no	15.471	15.827	EPSD	TCGA;ICGC;COSMIC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q13480	GAB1	P28482	MAPK1	T503	R507M	507	Missense	distal	4	no	16.804	16.639	EPSD	TCGA;ICGC;COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P10275	AR	P28482	MAPK1	T18	R13G	13	Missense	distal	-5	no	8.910	8.930	EPSD	TCGA;ICGC;COSMIC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P10275	AR	P28482	MAPK1	T18	P15L	15	Missense	distal	-3	no	8.910	8.526	EPSD	TCGA;ICGC;COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P10275	AR	P28482	MAPK1	T18	Y19C	19	Missense	proximal	1	no	8.910	2.471	EPSD	TCGA;ICGC	8.102	Loss
CMGC_MAPK_ERK1_MAPK1_ST	P10275	AR	P28482	MAPK1	T18	K17N	17	Missense	proximal	-1	no	8.910	8.903	EPSD	TCGA;ICGC;COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P10275	AR	P28482	MAPK1	S96	G95S	95	Missense	proximal	-1	no	11.382	11.393	EPSD	TCGA;ICGC;COSMIC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P10275	AR	P28482	MAPK1	S96	E93D	93	Missense	distal	-3	no	11.382	11.433	EPSD	TCGA;ICGC;COSMIC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P10275	AR	P28482	MAPK1	S258	R264W	264	Missense	distal	6	no	13.952	13.029	EPSD	TCGA;ICGC;COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P10275	AR	P28482	MAPK1	S258	A253V	253	Missense	distal	-5	no	13.952	13.923	EPSD	TCGA;ICGC;COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P10275	AR	P28482	MAPK1	T282	E289K	289	Missense	distal	7	no	13.218	13.226	EPSD	TCGA;ICGC;COSMIC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P10275	AR	P28482	MAPK1	T282	R280C	280	Missense	proximal	-2	no	13.218	11.271	EPSD	TCGA;ICGC;COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P10275	AR	P28482	MAPK1	S310	E308K	308	Missense	proximal	-2	no	12.629	12.589	EPSD	TCGA;COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P10275	AR	P28482	MAPK1	S310	Y316H	316	Missense	distal	6	no	12.629	12.942	EPSD	TCGA;ICGC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P10275	AR	P28482	MAPK1	S516	P513S	513	Missense	distal	-3	no	13.880	13.703	PhosphoSitePlus	TCGA;ICGC;COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P10275	AR	P28482	MAPK1	S651	E645K	645	Missense	distal	-6	no	15.833	15.808	EPSD	TCGA;ICGC;COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q14934	NFATC4	P28482	MAPK1	S819	G824V	824	Missense	distal	5	no	17.762	17.639	EPSD	TCGA;COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q13285	NR5A1	P28482	MAPK1	S203	P210L	210	Missense	distal	7	no	15.435	15.734	PhosphoSitePlus	TCGA;ICGC;COSMIC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P02686	MBP	P28482	MAPK1	S26	E25K	25	Missense	proximal	-1	no	8.090	8.118	EPSD	TCGA;ICGC;COSMIC	8.102	Gain
CMGC_MAPK_ERK1_MAPK1_ST	Q9UPT5	EXOC7	P28482	MAPK1	S130	D128N	128	Missense	proximal	-2	no	14.439	14.920	EPSD	TCGA;ICGC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q9UPT5	EXOC7	P28482	MAPK1	S242	S243Y	243	Missense	proximal	1	no	5.738	8.124	EPSD	TCGA;COSMIC	8.102	Gain
CMGC_MAPK_ERK1_MAPK1_ST	Q9UPT5	EXOC7	P28482	MAPK1	S250	S243Y	243	Missense	distal	-7	no	17.902	17.871	PhosphoSitePlus	TCGA;COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q9UPT5	EXOC7	P28482	MAPK1	T260	D259Y	259	Missense	proximal	-1	no	13.761	13.741	EPSD	TCGA;ICGC;COSMIC	8.102	Down-regulation
CMGC_GSK_GSK3B_ST	P49841	GSK3B	P49841-2	GSK3B	S25	Q19R	19	Missense	distal	-6	no	6.701	6.649	EPSD	TCGA	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	P49841	GSK3B	P49841-2	GSK3B	S25	S25N	25	Missense	central	0	yes	6.701	0.000	EPSD	TCGA;ICGC	6.007	Loss
CMGC_GSK_GSK3B_ST	P49841	GSK3B	P49841-2	GSK3B	S25	A22S	22	Missense	distal	-3	no	6.701	6.681	EPSD	TCGA;ICGC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	P49841	GSK3B	P49841-2	GSK3B	T43	D49N	49	Missense	distal	6	no	7.636	7.637	EPSD	TCGA;ICGC;COSMIC	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	P49841	GSK3B	P49841-2	GSK3B	S55	T59I	59	Missense	distal	4	no	7.192	4.739	EPSD	TCGA;ICGC;COSMIC	6.007	Loss
CMGC_GSK_GSK3B_ST	P49841	GSK3B	P49841-2	GSK3B	S55	D49N	49	Missense	distal	-6	no	7.192	7.215	EPSD	TCGA;ICGC;COSMIC	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	P49841	GSK3B	P49841-2	GSK3B	S215	Y216C	216	Missense	proximal	1	no	7.507	6.502	EPSD	TCGA;ICGC;COSMIC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	P49841	GSK3B	P49841-2	GSK3B	S215	S215L	215	Missense	central	0	yes	7.507	0.000	EPSD	TCGA;ICGC;COSMIC	6.007	Loss
CMGC_GSK_GSK3B_ST	P49841	GSK3B	P49841-2	GSK3B	S219	Y216C	216	Missense	distal	-3	no	6.818	6.781	EPSD	TCGA;ICGC;COSMIC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	P49841	GSK3B	P49841-2	GSK3B	S219	S215L	215	Missense	distal	-4	no	6.818	5.468	EPSD	TCGA;ICGC;COSMIC	6.007	Loss
CMGC_GSK_GSK3A_ST	P10636	MAPT	P49840	GSK3A	S46	T52I	52	Missense	distal	6	no	87.831	85.404	EPSD	TCGA;ICGC;COSMIC	72.838	Down-regulation
CMGC_GSK_GSK3A_ST	P10636	MAPT	P49840	GSK3A	S46	P47S	47	Missense	proximal	1	no	87.831	72.139	EPSD	TCGA;ICGC;COSMIC	72.838	Loss
CMGC_GSK_GSK3A_ST	P10636	MAPT	P49840	GSK3A	S46	P47L	47	Missense	proximal	1	no	87.831	73.780	EPSD	TCGA;ICGC;COSMIC	72.838	Down-regulation
CMGC_GSK_GSK3A_ST	P10636	MAPT	P49840	GSK3A	S46	G42C	42	Missense	distal	-4	no	87.831	68.590	EPSD	TCGA;ICGC;COSMIC	72.838	Loss
CMGC_GSK_GSK3A_ST	P10636	MAPT	P49840	GSK3A	T50	D54E	54	Missense	distal	4	no	87.484	87.867	EPSD	TCGA;ICGC;COSMIC	72.838	Up-regulation
CMGC_GSK_GSK3A_ST	P10636	MAPT	P49840	GSK3A	T50	T52I	52	Missense	proximal	2	no	87.484	83.704	EPSD	TCGA;ICGC;COSMIC	72.838	Down-regulation
CMGC_GSK_GSK3A_ST	P10636	MAPT	P49840	GSK3A	T50	P47S	47	Missense	distal	-3	no	87.484	86.844	EPSD	TCGA;ICGC;COSMIC	72.838	Down-regulation
CMGC_GSK_GSK3A_ST	P10636	MAPT	P49840	GSK3A	T50	P47L	47	Missense	distal	-3	no	87.484	85.739	EPSD	TCGA;ICGC;COSMIC	72.838	Down-regulation
CMGC_GSK_GSK3A_ST	P10636	MAPT	P49840	GSK3A	T50	G55R	55	Missense	distal	5	no	87.484	87.930	EPSD	TCGA;ICGC;COSMIC	72.838	Up-regulation
CMGC_GSK_GSK3A_ST	P10636	MAPT	P49840	GSK3A	T52	D54E	54	Missense	proximal	2	no	70.297	74.197	EPSD	TCGA;ICGC;COSMIC	72.838	Gain
CMGC_GSK_GSK3A_ST	P10636	MAPT	P49840	GSK3A	S56	G60S	60	Missense	distal	4	no	58.198	75.736	EPSD	TCGA;ICGC;COSMIC	72.838	Gain
CMGC_GSK_GSK3A_ST	P10636	MAPT	P49840	GSK3A	S61	D54E	54	Missense	distal	-7	no	71.444	72.937	EPSD	TCGA;ICGC;COSMIC	72.838	Gain
CMGC_GSK_GSK3A_ST	P10636	MAPT	P49840	GSK3A	S64	G60S	60	Missense	distal	-4	no	68.552	73.389	EPSD	TCGA;ICGC;COSMIC	72.838	Gain
CMGC_GSK_GSK3A_ST	P10636	MAPT	P49840	GSK3A	T101	H94R	94	Missense	distal	-7	no	73.952	71.885	EPSD	TCGA;ICGC;COSMIC	72.838	Loss
CMGC_GSK_GSK3A_ST	P10636	MAPT	P49840	GSK3A	T111	E117K	117	Missense	distal	6	no	74.941	75.486	EPSD	TCGA;ICGC;COSMIC	72.838	Up-regulation
CMGC_GSK_GSK3A_ST	P10636	MAPT	P49840	GSK3A	T111	A118V	118	Missense	distal	7	no	74.941	73.633	EPSD	TCGA;ICGC;COSMIC	72.838	Down-regulation
CMGC_GSK_GSK3A_ST	P10636	MAPT	P49840	GSK3A	S171	R168H	168	Missense	distal	-3	no	81.434	82.164	EPSD	TCGA;ICGC;COSMIC	72.838	Up-regulation
CMGC_GSK_GSK3A_ST	P10636	MAPT	P49840	GSK3A	S171	R168C	168	Missense	distal	-3	no	81.434	80.801	EPSD	TCGA;ICGC;COSMIC	72.838	Down-regulation
CMGC_GSK_GSK3A_ST	P10636	MAPT	P49840	GSK3A	S227	S232Y	232	Missense	distal	5	no	77.653	76.857	EPSD	TCGA;ICGC;COSMIC	72.838	Down-regulation
CMGC_GSK_GSK3A_ST	P10636	MAPT	P49840	GSK3A	S227	D223Y	223	Missense	distal	-4	no	77.653	78.451	EPSD	TCGA;ICGC;COSMIC	72.838	Up-regulation
CMGC_GSK_GSK3A_ST	P10636	MAPT	P49840	GSK3A	S227	E220K	220	Missense	distal	-7	no	77.653	78.241	EPSD	TCGA;ICGC;COSMIC	72.838	Up-regulation
CMGC_GSK_GSK3A_ST	P10636	MAPT	P49840	GSK3A	S227	S227F	227	Missense	central	0	yes	77.653	0.000	EPSD	TCGA;ICGC;COSMIC	72.838	Loss
CMGC_GSK_GSK3A_ST	P10636	MAPT	P49840	GSK3A	S227	P234L	234	Missense	distal	7	no	77.653	76.689	EPSD	TCGA;ICGC;COSMIC	72.838	Down-regulation
CMGC_GSK_GSK3A_ST	P10636	MAPT	P49840	GSK3A	S228	S232Y	232	Missense	distal	4	no	92.623	86.999	EPSD	TCGA;ICGC;COSMIC	72.838	Down-regulation
CMGC_GSK_GSK3A_ST	P10636	MAPT	P49840	GSK3A	S228	D223Y	223	Missense	distal	-5	no	92.623	94.564	EPSD	TCGA;ICGC;COSMIC	72.838	Up-regulation
CMGC_GSK_GSK3A_ST	P10636	MAPT	P49840	GSK3A	S228	S227F	227	Missense	proximal	-1	no	92.623	90.271	EPSD	TCGA;ICGC;COSMIC	72.838	Down-regulation
CMGC_GSK_GSK3A_ST	P10636	MAPT	P49840	GSK3A	S228	P234L	234	Missense	distal	6	no	92.623	89.743	EPSD	TCGA;ICGC;COSMIC	72.838	Down-regulation
CMGC_GSK_GSK3A_ST	P10636	MAPT	P49840	GSK3A	S232	S232Y	232	Missense	central	0	yes	85.793	0.000	EPSD	TCGA;ICGC;COSMIC	72.838	Loss
CMGC_GSK_GSK3A_ST	P10636	MAPT	P49840	GSK3A	S232	S227F	227	Missense	distal	-5	no	85.793	80.425	EPSD	TCGA;ICGC;COSMIC	72.838	Down-regulation
CMGC_GSK_GSK3A_ST	P10636	MAPT	P49840	GSK3A	S232	P234L	234	Missense	proximal	2	no	85.793	85.084	EPSD	TCGA;ICGC;COSMIC	72.838	Down-regulation
CMGC_GSK_GSK3A_ST	P10636	MAPT	P49840	GSK3A	S341	E348V	348	Missense	distal	7	no	79.730	78.144	EPSD	TCGA;ICGC;COSMIC	72.838	Down-regulation
CMGC_GSK_GSK3A_ST	P10636	MAPT	P49840	GSK3A	S341	G339R	339	Missense	proximal	-2	no	79.730	80.833	EPSD	TCGA;ICGC;COSMIC	72.838	Up-regulation
CMGC_GSK_GSK3A_ST	P10636	MAPT	P49840	GSK3A	S341	S341F	341	Missense	central	0	yes	79.730	0.000	EPSD	TCGA;ICGC;COSMIC	72.838	Loss
CMGC_GSK_GSK3A_ST	P10636	MAPT	P49840	GSK3A	S355	E348V	348	Missense	distal	-7	no	75.547	75.555	EPSD	TCGA;ICGC;COSMIC	72.838	Up-regulation
CMGC_GSK_GSK3A_ST	P10636	MAPT	P49840	GSK3A	S355	D350G	350	Missense	distal	-5	no	75.547	78.470	EPSD	TCGA;ICGC;COSMIC	72.838	Up-regulation
CMGC_GSK_GSK3A_ST	P10636	MAPT	P49840	GSK3A	S382	G387R	387	Missense	distal	5	no	82.900	83.346	EPSD	TCGA;COSMIC	72.838	Up-regulation
CMGC_GSK_GSK3A_ST	P10636	MAPT	P49840	GSK3A	S382	R377C	377	Missense	distal	-5	no	82.900	82.217	EPSD	TCGA;COSMIC	72.838	Down-regulation
CMGC_GSK_GSK3A_ST	P10636	MAPT	P49840	GSK3A	T386	G387R	387	Missense	proximal	1	no	78.953	80.776	EPSD	TCGA;COSMIC	72.838	Up-regulation
CMGC_GSK_GSK3A_ST	P10636	MAPT	P49840	GSK3A	S411	P415L	415	Missense	distal	4	no	99.189	99.766	EPSD	TCGA;ICGC;COSMIC	72.838	Up-regulation
CMGC_GSK_GSK3A_ST	P10636	MAPT	P49840	GSK3A	T416	P415L	415	Missense	proximal	-1	no	86.329	85.174	EPSD	TCGA;ICGC;COSMIC	72.838	Down-regulation
CMGC_GSK_GSK3A_ST	P10636	MAPT	P49840	GSK3A	S437	P436T	436	Missense	proximal	-1	no	72.985	73.771	EPSD	TCGA;ICGC;COSMIC	72.838	Up-regulation
CMGC_GSK_GSK3A_ST	P10636	MAPT	P49840	GSK3A	S437	P436L	436	Missense	proximal	-1	no	72.985	71.831	EPSD	TCGA;ICGC;COSMIC	72.838	Loss
CMGC_GSK_GSK3A_ST	P10636	MAPT	P49840	GSK3A	S437	K440E	440	Missense	distal	3	no	72.985	72.481	EPSD	TCGA;ICGC;COSMIC	72.838	Loss
CMGC_GSK_GSK3A_ST	P10636	MAPT	P49840	GSK3A	S437	S443F	443	Missense	distal	6	no	72.985	68.428	EPSD	TCGA;ICGC;COSMIC	72.838	Loss
CMGC_GSK_GSK3A_ST	P10636	MAPT	P49840	GSK3A	S437	A430S	430	Missense	distal	-7	no	72.985	72.027	EPSD	TCGA;ICGC;COSMIC	72.838	Loss
CMGC_GSK_GSK3A_ST	P10636	MAPT	P49840	GSK3A	S437	V431L	431	Missense	distal	-6	no	72.985	72.133	EPSD	TCGA;ICGC;COSMIC	72.838	Loss
CMGC_GSK_GSK3A_ST	P10636	MAPT	P49840	GSK3A	S437	S444F	444	Missense	distal	7	no	72.985	70.566	EPSD	TCGA;ICGC	72.838	Loss
CMGC_GSK_GSK3A_ST	P10636	MAPT	P49840	GSK3A	S437	A430V	430	Missense	distal	-7	no	72.985	72.111	EPSD	TCGA;ICGC;COSMIC	72.838	Loss
CMGC_GSK_GSK3A_ST	P10636	MAPT	P49840	GSK3A	S438	P436T	436	Missense	proximal	-2	no	99.970	99.401	EPSD	TCGA;ICGC;COSMIC	72.838	Down-regulation
CMGC_GSK_GSK3A_ST	P10636	MAPT	P49840	GSK3A	S438	P436L	436	Missense	proximal	-2	no	99.970	99.103	EPSD	TCGA;ICGC;COSMIC	72.838	Down-regulation
CMGC_GSK_GSK3A_ST	P10636	MAPT	P49840	GSK3A	S438	K440E	440	Missense	proximal	2	no	99.970	99.048	EPSD	TCGA;ICGC;COSMIC	72.838	Down-regulation
CMGC_GSK_GSK3A_ST	P10636	MAPT	P49840	GSK3A	S438	S443F	443	Missense	distal	5	no	99.970	102.480	EPSD	TCGA;ICGC;COSMIC	72.838	Up-regulation
CMGC_GSK_GSK3A_ST	P10636	MAPT	P49840	GSK3A	S438	V431L	431	Missense	distal	-7	no	99.970	98.210	EPSD	TCGA;ICGC;COSMIC	72.838	Down-regulation
CMGC_GSK_GSK3A_ST	P10636	MAPT	P49840	GSK3A	S438	S444F	444	Missense	distal	6	no	99.970	95.413	EPSD	TCGA;ICGC	72.838	Down-regulation
CMGC_GSK_GSK3A_ST	P10636	MAPT	P49840	GSK3A	S447	K440E	440	Missense	distal	-7	no	81.913	81.324	EPSD	TCGA;ICGC;COSMIC	72.838	Down-regulation
CMGC_GSK_GSK3A_ST	P10636	MAPT	P49840	GSK3A	S447	S452C	452	Missense	distal	5	no	81.913	68.631	EPSD	TCGA;ICGC;COSMIC	72.838	Loss
CMGC_GSK_GSK3A_ST	P10636	MAPT	P49840	GSK3A	S447	S443F	443	Missense	distal	-4	no	81.913	74.154	EPSD	TCGA;ICGC;COSMIC	72.838	Down-regulation
CMGC_GSK_GSK3A_ST	P10636	MAPT	P49840	GSK3A	S447	S444F	444	Missense	distal	-3	no	81.913	80.684	EPSD	TCGA;ICGC	72.838	Down-regulation
CMGC_GSK_GSK3A_ST	P10636	MAPT	P49840	GSK3A	S447	S452Y	452	Missense	distal	5	no	81.913	81.117	EPSD	TCGA;ICGC;COSMIC	72.838	Down-regulation
CMGC_GSK_GSK3A_ST	P10636	MAPT	P49840	GSK3A	S451	E456K	456	Missense	distal	5	no	82.495	78.418	EPSD	TCGA;ICGC;COSMIC	72.838	Down-regulation
CMGC_GSK_GSK3A_ST	P10636	MAPT	P49840	GSK3A	S451	S452C	452	Missense	proximal	1	no	82.495	71.145	EPSD	TCGA;ICGC;COSMIC	72.838	Loss
CMGC_GSK_GSK3A_ST	P10636	MAPT	P49840	GSK3A	S451	S444F	444	Missense	distal	-7	no	82.495	79.417	EPSD	TCGA;ICGC	72.838	Down-regulation
CMGC_GSK_GSK3A_ST	P10636	MAPT	P49840	GSK3A	S451	S452Y	452	Missense	proximal	1	no	82.495	90.578	EPSD	TCGA;ICGC;COSMIC	72.838	Up-regulation
CMGC_GSK_GSK3A_ST	P10636	MAPT	P49840	GSK3A	T466	R472Q	472	Missense	distal	6	no	84.654	85.708	EPSD	TCGA	72.838	Up-regulation
CMGC_GSK_GSK3A_ST	P10636	MAPT	P49840	GSK3A	T466	R472W	472	Missense	distal	6	no	84.654	77.162	EPSD	TCGA;COSMIC	72.838	Down-regulation
CMGC_GSK_GSK3A_ST	P10636	MAPT	P49840	GSK3A	T466	L459R	459	Missense	distal	-7	no	84.654	85.424	EPSD	TCGA;ICGC;COSMIC	72.838	Up-regulation
CMGC_GSK_GSK3A_ST	P10636	MAPT	P49840	GSK3A	T466	L459F	459	Missense	distal	-7	no	84.654	83.252	EPSD	TCGA;ICGC	72.838	Down-regulation
CMGC_GSK_GSK3A_ST	P10636	MAPT	P49840	GSK3A	T470	R472Q	472	Missense	proximal	2	no	87.288	86.690	EPSD	TCGA	72.838	Down-regulation
CMGC_GSK_GSK3A_ST	P10636	MAPT	P49840	GSK3A	T470	R472W	472	Missense	proximal	2	no	87.288	83.809	EPSD	TCGA;COSMIC	72.838	Down-regulation
CMGC_GSK_GSK3A_ST	P10636	MAPT	P49840	GSK3A	T492	A485T	485	Missense	distal	-7	no	79.582	79.471	EPSD	TCGA;COSMIC;GDSC;CCLE	72.838	Down-regulation
CMGC_GSK_GSK3A_ST	P10636	MAPT	P49840	GSK3A	T492	P493Q	493	Missense	proximal	1	no	79.582	68.905	EPSD	TCGA;COSMIC	72.838	Loss
CMGC_GSK_GSK3A_ST	P10636	MAPT	P49840	GSK3A	T498	P493Q	493	Missense	distal	-5	no	93.228	93.990	EPSD	TCGA;COSMIC	72.838	Up-regulation
CMGC_GSK_GSK3A_ST	Q14449	GRB14	P49840	GSK3A	S358	Q363H	363	Missense	distal	5	no	77.640	76.399	EPSD;PhosphoSitePlus	TCGA;COSMIC	72.838	Down-regulation
CMGC_GSK_GSK3A_ST	Q14449	GRB14	P49840	GSK3A	S362	Q363H	363	Missense	proximal	1	no	81.324	65.586	PhosphoSitePlus;EPSD	TCGA;COSMIC	72.838	Loss
CMGC_GSK_GSK3A_ST	Q14449	GRB14	P49840	GSK3A	S366	E373K	373	Missense	distal	7	no	87.312	87.458	EPSD;PhosphoSitePlus	TCGA;COSMIC	72.838	Up-regulation
CMGC_GSK_GSK3A_ST	Q14449	GRB14	P49840	GSK3A	S366	Q363H	363	Missense	distal	-3	no	87.312	88.392	EPSD;PhosphoSitePlus	TCGA;COSMIC	72.838	Up-regulation
CMGC_GSK_GSK3A_ST	Q14449	GRB14	P49840	GSK3A	S370	E373K	373	Missense	distal	3	no	72.741	73.246	EPSD	TCGA;COSMIC	72.838	Gain
CMGC_GSK_GSK3A_ST	Q14449	GRB14	P49840	GSK3A	S370	S375F	375	Missense	distal	5	no	72.741	75.251	EPSD	TCGA;ICGC;COSMIC	72.838	Gain
CMGC_GSK_GSK3A_ST	Q14449	GRB14	P49840	GSK3A	S370	Q363H	363	Missense	distal	-7	no	72.741	74.596	EPSD	TCGA;COSMIC	72.838	Gain
CMGC_GSK_GSK3A_ST	Q14449	GRB14	P49840	GSK3A	S419	L414R	414	Missense	distal	-5	no	86.918	86.894	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	72.838	Down-regulation
CMGC_GSK_GSK3A_ST	Q14449	GRB14	P49840	GSK3A	S419	H417Y	417	Missense	proximal	-2	no	86.918	87.059	EPSD;PhosphoSitePlus	TCGA;COSMIC	72.838	Up-regulation
CMGC_GSK_GSK3A_ST	Q14449	GRB14	P49840	GSK3A	S419	S419I	419	Missense	central	0	yes	86.918	0.000	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	72.838	Loss
CMGC_GSK_GSK3A_ST	Q14449	GRB14	P49840	GSK3A	S419	S426I	426	Missense	distal	7	no	86.918	86.812	EPSD;PhosphoSitePlus	TCGA	72.838	Down-regulation
CMGC_GSK_GSK3A_ST	Q14449	GRB14	P49840	GSK3A	S423	H417Y	417	Missense	distal	-6	no	78.862	78.665	EPSD;PhosphoSitePlus	TCGA;COSMIC	72.838	Down-regulation
CMGC_GSK_GSK3A_ST	Q14449	GRB14	P49840	GSK3A	S423	S419I	419	Missense	distal	-4	no	78.862	73.078	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	72.838	Down-regulation
CMGC_GSK_GSK3A_ST	Q14449	GRB14	P49840	GSK3A	S423	S426I	426	Missense	distal	3	no	78.862	78.161	EPSD;PhosphoSitePlus	TCGA	72.838	Down-regulation
CMGC_GSK_GSK3A_ST	Q14449	GRB14	P49840	GSK3A	S423	A428D	428	Missense	distal	5	no	78.862	78.469	EPSD;PhosphoSitePlus	TCGA;ICGC	72.838	Down-regulation
CMGC_GSK_GSK3A_ST	Q14449	GRB14	P49840	GSK3A	S424	H417Y	417	Missense	distal	-7	no	88.602	88.185	EPSD	TCGA;COSMIC	72.838	Down-regulation
CMGC_GSK_GSK3A_ST	Q14449	GRB14	P49840	GSK3A	S424	S419I	419	Missense	distal	-5	no	88.602	86.680	EPSD	TCGA;ICGC;COSMIC	72.838	Down-regulation
CMGC_GSK_GSK3A_ST	Q14449	GRB14	P49840	GSK3A	S424	S426I	426	Missense	proximal	2	no	88.602	86.234	EPSD	TCGA	72.838	Down-regulation
CMGC_GSK_GSK3A_ST	Q14449	GRB14	P49840	GSK3A	S424	A428D	428	Missense	distal	4	no	88.602	87.346	EPSD	TCGA;ICGC	72.838	Down-regulation
CMGC_GSK_GSK3A_ST	O75581	LRP6	P49840	GSK3A	S1440	S1435T	1435	Missense	distal	-5	no	76.527	76.199	EPSD	TCGA	72.838	Down-regulation
CMGC_GSK_GSK3A_ST	O75581	LRP6	P49840	GSK3A	S1440	S1447C	1447	Missense	distal	7	no	76.527	75.714	EPSD	TCGA;COSMIC	72.838	Down-regulation
CMGC_GSK_GSK3A_ST	O75581	LRP6	P49840	GSK3A	S1440	R1441Q	1441	Missense	proximal	1	no	76.527	74.503	EPSD	TCGA;COSMIC	72.838	Down-regulation
CMGC_GSK_GSK3A_ST	O75581	LRP6	P49840	GSK3A	S1440	S1433A	1433	Missense	distal	-7	no	76.527	77.485	EPSD	TCGA	72.838	Up-regulation
CMGC_GSK_GSK3A_ST	O75581	LRP6	P49840	GSK3A	S1440	M1445I	1445	Missense	distal	5	no	76.527	65.182	EPSD	TCGA;COSMIC	72.838	Loss
CMGC_GSK_GSK3A_ST	O75581	LRP6	P49840	GSK3A	S1455	R1462P	1462	Missense	distal	7	no	72.730	73.607	EPSD	TCGA;COSMIC	72.838	Gain
CMGC_GSK_GSK3A_ST	O75581	LRP6	P49840	GSK3A	S1510	G1503E	1503	Missense	distal	-7	no	74.967	74.849	EPSD	TCGA;COSMIC	72.838	Down-regulation
CMGC_GSK_GSK3A_ST	O75581	LRP6	P49840	GSK3A	S1510	S1505Y	1505	Missense	distal	-5	no	74.967	73.801	EPSD	TCGA	72.838	Down-regulation
CMGC_GSK_GSK3A_ST	O75581	LRP6	P49840	GSK3A	S1516	R1523W	1523	Missense	distal	7	no	80.230	80.228	EPSD	TCGA;COSMIC	72.838	Down-regulation
CMGC_GSK_GSK3A_ST	O75581	LRP6	P49840	GSK3A	S1516	P1519S	1519	Missense	distal	3	no	80.230	78.897	EPSD	TCGA;COSMIC	72.838	Down-regulation
CMGC_GSK_GSK3A_ST	O75581	LRP6	P49840	GSK3A	S1521	R1523W	1523	Missense	proximal	2	no	74.896	71.417	EPSD	TCGA;COSMIC	72.838	Loss
CMGC_GSK_GSK3A_ST	O75581	LRP6	P49840	GSK3A	S1521	H1524Q	1524	Missense	distal	3	no	74.896	69.051	EPSD	TCGA;COSMIC	72.838	Loss
CMGC_GSK_GSK3A_ST	O75581	LRP6	P49840	GSK3A	S1521	H1524Y	1524	Missense	distal	3	no	74.896	74.494	EPSD	TCGA	72.838	Down-regulation
CMGC_GSK_GSK3A_ST	O75581	LRP6	P49840	GSK3A	S1521	P1519S	1519	Missense	proximal	-2	no	74.896	74.744	EPSD	TCGA;COSMIC	72.838	Down-regulation
CMGC_GSK_GSK3A_ST	O75581	LRP6	P49840	GSK3A	T1530	R1523W	1523	Missense	distal	-7	no	83.729	82.347	EPSD	TCGA;COSMIC	72.838	Down-regulation
CMGC_GSK_GSK3A_ST	O75581	LRP6	P49840	GSK3A	T1530	H1524Q	1524	Missense	distal	-6	no	83.729	83.612	EPSD	TCGA;COSMIC	72.838	Down-regulation
CMGC_GSK_GSK3A_ST	O75581	LRP6	P49840	GSK3A	T1530	H1524Y	1524	Missense	distal	-6	no	83.729	83.532	EPSD	TCGA	72.838	Down-regulation
CMGC_GSK_GSK3A_ST	O75581	LRP6	P49840	GSK3A	S1544	Y1541S	1541	Missense	distal	-3	no	87.483	86.623	PhosphoSitePlus	TCGA;COSMIC	72.838	Down-regulation
CMGC_GSK_GSK3A_ST	O75581	LRP6	P49840	GSK3A	S1544	R1545Q	1545	Missense	proximal	1	no	87.483	85.460	PhosphoSitePlus	TCGA;COSMIC	72.838	Down-regulation
CMGC_GSK_GSK3A_ST	O75581	LRP6	P49840	GSK3A	T1548	Y1541S	1541	Missense	distal	-7	no	76.065	75.321	EPSD	TCGA;COSMIC	72.838	Down-regulation
CMGC_GSK_GSK3A_ST	O75581	LRP6	P49840	GSK3A	T1548	R1545Q	1545	Missense	distal	-3	no	76.065	75.716	EPSD	TCGA;COSMIC	72.838	Down-regulation
CMGC_GSK_GSK3A_ST	O75581	LRP6	P49840	GSK3A	S1579	S1579P	1579	Missense	central	0	yes	82.420	0.000	EPSD	TCGA;COSMIC	72.838	Loss
CMGC_GSK_GSK3A_ST	O75581	LRP6	P49840	GSK3A	S1579	R1574Q	1574	Missense	distal	-5	no	82.420	84.769	EPSD	TCGA;COSMIC	72.838	Up-regulation
CMGC_GSK_GSK3A_ST	O75581	LRP6	P49840	GSK3A	S1586	S1579P	1579	Missense	distal	-7	no	78.359	78.514	EPSD	TCGA;COSMIC	72.838	Up-regulation
CMGC_GSK_GSK3A_ST	O75581	LRP6	P49840	GSK3A	S1590	S1596G	1596	Missense	distal	6	no	84.387	83.433	EPSD	TCGA;COSMIC	72.838	Down-regulation
CMGC_GSK_GSK3A_ST	O75581	LRP6	P49840	GSK3A	T1593	S1596G	1596	Missense	distal	3	no	73.183	72.576	EPSD	TCGA;COSMIC	72.838	Loss
CMGC_GSK_GSK3A_ST	O75581	LRP6	P49840	GSK3A	T1593	H1599D	1599	Missense	distal	6	no	73.183	70.059	EPSD	TCGA;COSMIC	72.838	Loss
CMGC_GSK_GSK3A_ST	Q14596	NBR1	P49840	GSK3A	S273	P269S	269	Missense	distal	-4	no	71.282	74.868	EPSD	TCGA;ICGC;COSMIC	72.838	Gain
CMGC_GSK_GSK3A_ST	Q14596	NBR1	P49840	GSK3A	S276	H272D	272	Missense	distal	-4	no	81.543	80.268	EPSD	TCGA;ICGC;COSMIC	72.838	Down-regulation
CMGC_GSK_GSK3A_ST	Q14596	NBR1	P49840	GSK3A	S276	S276C	276	Missense	central	0	yes	81.543	0.000	EPSD	TCGA;ICGC;COSMIC	72.838	Loss
CMGC_GSK_GSK3A_ST	Q14596	NBR1	P49840	GSK3A	S276	P269S	269	Missense	distal	-7	no	81.543	81.388	EPSD	TCGA;ICGC;COSMIC	72.838	Down-regulation
CMGC_GSK_GSK3A_ST	Q14596	NBR1	P49840	GSK3A	S276	P269L	269	Missense	distal	-7	no	81.543	79.712	EPSD	TCGA;ICGC;COSMIC	72.838	Down-regulation
CMGC_GSK_GSK3A_ST	Q14596	NBR1	P49840	GSK3A	S340	I335F	335	Missense	distal	-5	no	77.016	73.570	EPSD	TCGA;ICGC	72.838	Down-regulation
CMGC_GSK_GSK3A_ST	Q14596	NBR1	P49840	GSK3A	S340	P344S	344	Missense	distal	4	no	77.016	83.002	EPSD	TCGA;ICGC;COSMIC	72.838	Up-regulation
CMGC_GSK_GSK3A_ST	Q14596	NBR1	P49840	GSK3A	S340	P341L	341	Missense	proximal	1	no	77.016	62.964	EPSD	TCGA;ICGC	72.838	Loss
CMGC_GSK_GSK3A_ST	Q14596	NBR1	P49840	GSK3A	S486	P482S	482	Missense	distal	-4	no	80.625	84.212	EPSD	TCGA;ICGC;COSMIC	72.838	Up-regulation
CMGC_GSK_GSK3A_ST	Q14596	NBR1	P49840	GSK3A	S486	E484K	484	Missense	proximal	-2	no	80.625	81.987	EPSD	TCGA;ICGC	72.838	Up-regulation
CMGC_GSK_GSK3A_ST	Q14596	NBR1	P49840	GSK3A	T586	P582S	582	Missense	distal	-4	no	83.710	87.296	PhosphoSitePlus	TCGA;ICGC	72.838	Up-regulation
CMGC_GSK_GSK3A_ST	Q14596	NBR1	P49840	GSK3A	T586	P582H	582	Missense	distal	-4	no	83.710	86.892	PhosphoSitePlus	TCGA;ICGC;COSMIC	72.838	Up-regulation
CMGC_GSK_GSK3A_ST	Q14596	NBR1	P49840	GSK3A	T586	T586I	586	Missense	central	0	yes	83.710	0.000	PhosphoSitePlus	TCGA;ICGC;COSMIC	72.838	Loss
CMGC_GSK_GSK3A_ST	P20749	BCL3	P49840	GSK3A	S122	L121F	121	Missense	proximal	-1	no	79.588	77.495	EPSD	TCGA	72.838	Down-regulation
CMGC_GSK_GSK3A_ST	P20749	BCL3	P49840	GSK3A	S122	P116S	116	Missense	distal	-6	no	79.588	79.534	EPSD	TCGA;ICGC;COSMIC	72.838	Down-regulation
CMGC_GSK_GSK3A_ST	P20749	BCL3	P49840	GSK3A	S122	M117I	117	Missense	distal	-5	no	79.588	79.963	EPSD	TCGA;ICGC;COSMIC	72.838	Up-regulation
CMGC_GSK_GSK3A_ST	P20749	BCL3	P49840	GSK3A	S122	D124E	124	Missense	proximal	2	no	79.588	83.488	EPSD	TCGA;ICGC;COSMIC	72.838	Up-regulation
CMGC_GSK_GSK3A_ST	P20749	BCL3	P49840	GSK3A	S122	A123T	123	Missense	proximal	1	no	79.588	78.604	EPSD	TCGA;ICGC;COSMIC	72.838	Down-regulation
CMGC_GSK_GSK3A_ST	P20749	BCL3	P49840	GSK3A	S197	R203H	203	Missense	distal	6	no	82.065	83.546	EPSD	TCGA;ICGC	72.838	Up-regulation
CMGC_GSK_GSK3A_ST	P20749	BCL3	P49840	GSK3A	T363	I357M	357	Missense	distal	-6	no	81.408	81.616	EPSD	TCGA;ICGC;COSMIC	72.838	Up-regulation
CMGC_GSK_GSK3A_ST	P20749	BCL3	P49840	GSK3A	S367	P373L	373	Missense	distal	6	no	83.205	80.325	EPSD	TCGA;ICGC;COSMIC	72.838	Down-regulation
CMGC_GSK_GSK3A_ST	P20749	BCL3	P49840	GSK3A	S369	P373L	373	Missense	distal	4	no	75.204	75.781	EPSD	TCGA;ICGC;COSMIC	72.838	Up-regulation
CMGC_GSK_GSK3A_ST	P20749	BCL3	P49840	GSK3A	S374	P373L	373	Missense	proximal	-1	no	88.220	87.065	EPSD	TCGA;ICGC;COSMIC	72.838	Down-regulation
CMGC_GSK_GSK3A_ST	P20749	BCL3	P49840	GSK3A	S378	P373L	373	Missense	distal	-5	no	85.952	84.388	EPSD	TCGA;ICGC;COSMIC	72.838	Down-regulation
CMGC_GSK_GSK3A_ST	P20749	BCL3	P49840	GSK3A	S378	E384K	384	Missense	distal	6	no	85.952	86.497	EPSD	TCGA;ICGC;COSMIC	72.838	Up-regulation
CMGC_GSK_GSK3A_ST	P20749	BCL3	P49840	GSK3A	S382	E384K	384	Missense	proximal	2	no	92.236	93.158	EPSD	TCGA;ICGC;COSMIC	72.838	Up-regulation
CMGC_GSK_GSK3A_ST	P20749	BCL3	P49840	GSK3A	S402	S396F	396	Missense	distal	-6	no	97.336	98.966	PhosphoSitePlus;EPSD	TCGA;ICGC;COSMIC	72.838	Up-regulation
CMGC_GSK_GSK3A_ST	P20749	BCL3	P49840	GSK3A	S402	Q405K	405	Missense	distal	3	no	97.336	101.111	PhosphoSitePlus;EPSD	TCGA;ICGC;COSMIC	72.838	Up-regulation
CMGC_GSK_GSK3A_ST	P20749	BCL3	P49840	GSK3A	S402	P408H	408	Missense	distal	6	no	97.336	99.672	PhosphoSitePlus;EPSD	TCGA;ICGC	72.838	Up-regulation
CMGC_GSK_GSK3A_ST	P20749	BCL3	P49840	GSK3A	S402	P407T	407	Missense	distal	5	no	97.336	92.456	PhosphoSitePlus;EPSD	TCGA;ICGC;COSMIC	72.838	Down-regulation
CMGC_GSK_GSK3A_ST	P20749	BCL3	P49840	GSK3A	S406	Q405K	405	Missense	proximal	-1	no	104.218	102.384	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	72.838	Down-regulation
CMGC_GSK_GSK3A_ST	P20749	BCL3	P49840	GSK3A	S406	P408H	408	Missense	proximal	2	no	104.218	102.895	EPSD;PhosphoSitePlus	TCGA;ICGC	72.838	Down-regulation
CMGC_GSK_GSK3A_ST	P20749	BCL3	P49840	GSK3A	S406	P407T	407	Missense	proximal	1	no	104.218	89.566	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	72.838	Down-regulation
CMGC_GSK_GSK3A_ST	P49840	GSK3A	P49840	GSK3A	S282	R283H	283	Missense	proximal	1	no	74.809	57.047	EPSD	TCGA;ICGC;COSMIC	72.838	Loss
CMGC_GSK_GSK3A_ST	P49840	GSK3A	P49840	GSK3A	S282	Y284H	284	Missense	proximal	2	no	74.809	74.295	EPSD	TCGA;ICGC;COSMIC	72.838	Down-regulation
CMGC_GSK_GSK3A_ST	P22415	USF1	P49840	GSK3A	T153	P155L	155	Missense	proximal	2	no	90.075	89.366	EPSD;PhosphoSitePlus	TCGA;COSMIC	72.838	Down-regulation
CMGC_GSK_GSK3A_ST	P22415	USF1	P49840	GSK3A	T153	P154L	154	Missense	proximal	1	no	90.075	76.024	EPSD;PhosphoSitePlus	TCGA;COSMIC	72.838	Down-regulation
CMGC_GSK_GSK3A_ST	P22415	USF1	P49840	GSK3A	S186	P192L	192	Missense	distal	6	no	92.592	89.712	PhosphoSitePlus;EPSD	TCGA;COSMIC	72.838	Down-regulation
CMGC_GSK_GSK3A_ST	P22415	USF1	P49840	GSK3A	T195	R201S	201	Missense	distal	6	no	79.029	77.623	EPSD	TCGA;COSMIC	72.838	Down-regulation
CMGC_GSK_GSK3A_ST	P22415	USF1	P49840	GSK3A	T195	R196W	196	Missense	proximal	1	no	79.029	14.987	EPSD	TCGA;ICGC;COSMIC	72.838	Loss
CMGC_GSK_GSK3A_ST	P22415	USF1	P49840	GSK3A	T195	P192L	192	Missense	distal	-3	no	79.029	77.284	EPSD	TCGA;COSMIC	72.838	Down-regulation
CMGC_GSK_GSK3A_ST	P22415	USF1	P49840	GSK3A	T195	E198A	198	Missense	distal	3	no	79.029	77.948	EPSD	TCGA	72.838	Down-regulation
CMGC_GSK_GSK3A_ST	Q96F46	IL17RA	P49840	GSK3A	T780	P778S	778	Missense	proximal	-2	no	90.191	90.039	PhosphoSitePlus	TCGA;ICGC	72.838	Down-regulation
CMGC_GSK_GSK3A_ST	Q96F46	IL17RA	P49840	GSK3A	S801	S798P	798	Missense	distal	-3	no	81.014	81.653	EPSD	TCGA;ICGC;COSMIC	72.838	Up-regulation
CMGC_GSK_GSK3A_ST	P17661	DES	P49840	GSK3A	S46	K43E	43	Missense	distal	-3	no	72.830	74.135	EPSD	TCGA;ICGC;COSMIC	72.838	Gain
CMGC_GSK_GSK3A_ST	P17661	DES	P49840	GSK3A	S68	G61V	61	Missense	distal	-7	no	86.365	86.256	EPSD	TCGA;ICGC;COSMIC	72.838	Down-regulation
CMGC_GSK_GSK3A_ST	P17661	DES	P49840	GSK3A	S72	R78H	78	Missense	distal	6	no	102.399	103.880	EPSD	TCGA;ICGC;COSMIC	72.838	Up-regulation
CMGC_GSK_GSK3A_ST	P17661	DES	P49840	GSK3A	T76	R78H	78	Missense	proximal	2	no	76.484	75.647	EPSD	TCGA;ICGC;COSMIC	72.838	Down-regulation
CMGC_GSK_GSK3A_ST	P35222	CTNNB1	P49840	GSK3A	S33	G34R	34	Missense	proximal	1	no	93.350	95.173	EPSD;PhosphoSitePlus	TCGA;COSMIC	72.838	Up-regulation
CMGC_GSK_GSK3A_ST	P35222	CTNNB1	P49840	GSK3A	S33	G34V	34	Missense	proximal	1	no	93.350	80.336	EPSD;PhosphoSitePlus	TCGA;COSMIC;CCLE	72.838	Down-regulation
CMGC_GSK_GSK3A_ST	P35222	CTNNB1	P49840	GSK3A	S33	G34E	34	Missense	proximal	1	no	93.350	85.301	EPSD;PhosphoSitePlus	TCGA;COSMIC;GDSC;CCLE	72.838	Down-regulation
CMGC_GSK_GSK3A_ST	P35222	CTNNB1	P49840	GSK3A	S33	S37C	37	Missense	distal	4	no	93.350	19.937	EPSD;PhosphoSitePlus	TCGA;COSMIC;GDSC;CCLE	72.838	Loss
CMGC_GSK_GSK3A_ST	P35222	CTNNB1	P49840	GSK3A	S33	S37F	37	Missense	distal	4	no	93.350	71.060	EPSD;PhosphoSitePlus	TCGA;COSMIC;GDSC;CCLE	72.838	Loss
CMGC_GSK_GSK3A_ST	P35222	CTNNB1	P49840	GSK3A	S33	S33F	33	Missense	central	0	yes	93.350	0.000	EPSD;PhosphoSitePlus	TCGA;COSMIC;GDSC;CCLE	72.838	Loss
CMGC_GSK_GSK3A_ST	P35222	CTNNB1	P49840	GSK3A	S33	D32H	32	Missense	proximal	-1	no	93.350	94.142	EPSD;PhosphoSitePlus	TCGA;COSMIC	72.838	Up-regulation
CMGC_GSK_GSK3A_ST	P35222	CTNNB1	P49840	GSK3A	S33	D32G	32	Missense	proximal	-1	no	93.350	93.968	EPSD;PhosphoSitePlus	TCGA;COSMIC	72.838	Up-regulation
CMGC_GSK_GSK3A_ST	P35222	CTNNB1	P49840	GSK3A	S33	S33A	33	Missense	central	0	yes	93.350	0.000	EPSD;PhosphoSitePlus	TCGA;COSMIC	72.838	Loss
CMGC_GSK_GSK3A_ST	P35222	CTNNB1	P49840	GSK3A	S33	S33Y	33	Missense	central	0	yes	93.350	0.000	EPSD;PhosphoSitePlus	TCGA;COSMIC;GDSC;CCLE	72.838	Loss
CMGC_GSK_GSK3A_ST	P35222	CTNNB1	P49840	GSK3A	S33	D32V	32	Missense	proximal	-1	no	93.350	94.225	EPSD;PhosphoSitePlus	TCGA;COSMIC;CCLE	72.838	Up-regulation
CMGC_GSK_GSK3A_ST	P35222	CTNNB1	P49840	GSK3A	S33	S33P	33	Missense	central	0	yes	93.350	0.000	EPSD;PhosphoSitePlus	TCGA;COSMIC;CCLE	72.838	Loss
CMGC_GSK_GSK3A_ST	P35222	CTNNB1	P49840	GSK3A	S33	H36P	36	Missense	distal	3	no	93.350	90.386	EPSD;PhosphoSitePlus	TCGA;COSMIC;CCLE	72.838	Down-regulation
CMGC_GSK_GSK3A_ST	P35222	CTNNB1	P49840	GSK3A	S33	D32Y	32	Missense	proximal	-1	no	93.350	95.313	EPSD;PhosphoSitePlus	TCGA;COSMIC;CCLE	72.838	Up-regulation
CMGC_GSK_GSK3A_ST	P35222	CTNNB1	P49840	GSK3A	S33	I35S	35	Missense	proximal	2	no	93.350	95.718	EPSD;PhosphoSitePlus	TCGA;COSMIC	72.838	Up-regulation
CMGC_GSK_GSK3A_ST	P35222	CTNNB1	P49840	GSK3A	S33	S37Y	37	Missense	distal	4	no	93.350	87.727	EPSD;PhosphoSitePlus	TCGA;COSMIC	72.838	Down-regulation
CMGC_GSK_GSK3A_ST	P35222	CTNNB1	P49840	GSK3A	S33	S33C	33	Missense	central	0	yes	93.350	0.000	EPSD;PhosphoSitePlus	TCGA;COSMIC;GDSC;CCLE	72.838	Loss
CMGC_GSK_GSK3A_ST	P35222	CTNNB1	P49840	GSK3A	S33	S37A	37	Missense	distal	4	no	93.350	90.265	EPSD;PhosphoSitePlus	TCGA;COSMIC;GDSC;CCLE	72.838	Down-regulation
CMGC_GSK_GSK3A_ST	P35222	CTNNB1	P49840	GSK3A	S33	D32N	32	Missense	proximal	-1	no	93.350	93.404	EPSD;PhosphoSitePlus	TCGA;COSMIC;CCLE	72.838	Up-regulation
CMGC_GSK_GSK3A_ST	P35222	CTNNB1	P49840	GSK3A	S33	S37P	37	Missense	distal	4	no	93.350	87.364	EPSD;PhosphoSitePlus	TCGA;COSMIC;GDSC;CCLE	72.838	Down-regulation
CMGC_GSK_GSK3A_ST	P35222	CTNNB1	P49840	GSK3A	S33	D32A	32	Missense	proximal	-1	no	93.350	94.766	EPSD;PhosphoSitePlus	TCGA;COSMIC	72.838	Up-regulation
CMGC_GSK_GSK3A_ST	P35222	CTNNB1	P49840	GSK3A	S37	G34R	34	Missense	distal	-3	no	82.758	82.923	PhosphoSitePlus;EPSD	TCGA;COSMIC	72.838	Up-regulation
CMGC_GSK_GSK3A_ST	P35222	CTNNB1	P49840	GSK3A	S37	G34V	34	Missense	distal	-3	no	82.758	83.308	PhosphoSitePlus;EPSD	TCGA;COSMIC;CCLE	72.838	Up-regulation
CMGC_GSK_GSK3A_ST	P35222	CTNNB1	P49840	GSK3A	S37	T41A	41	Missense	distal	4	no	82.758	80.173	PhosphoSitePlus;EPSD	TCGA;COSMIC;GDSC;CCLE	72.838	Down-regulation
CMGC_GSK_GSK3A_ST	P35222	CTNNB1	P49840	GSK3A	S37	G34E	34	Missense	distal	-3	no	82.758	83.830	PhosphoSitePlus;EPSD	TCGA;COSMIC;GDSC;CCLE	72.838	Up-regulation
CMGC_GSK_GSK3A_ST	P35222	CTNNB1	P49840	GSK3A	S37	S37C	37	Missense	central	0	yes	82.758	0.000	PhosphoSitePlus;EPSD	TCGA;COSMIC;GDSC;CCLE	72.838	Loss
CMGC_GSK_GSK3A_ST	P35222	CTNNB1	P49840	GSK3A	S37	S37F	37	Missense	central	0	yes	82.758	0.000	PhosphoSitePlus;EPSD	TCGA;COSMIC;GDSC;CCLE	72.838	Loss
CMGC_GSK_GSK3A_ST	P35222	CTNNB1	P49840	GSK3A	S37	S33F	33	Missense	distal	-4	no	82.758	75.000	PhosphoSitePlus;EPSD	TCGA;COSMIC;GDSC;CCLE	72.838	Down-regulation
CMGC_GSK_GSK3A_ST	P35222	CTNNB1	P49840	GSK3A	S37	D32H	32	Missense	distal	-5	no	82.758	84.392	PhosphoSitePlus;EPSD	TCGA;COSMIC	72.838	Up-regulation
CMGC_GSK_GSK3A_ST	P35222	CTNNB1	P49840	GSK3A	S37	D32G	32	Missense	distal	-5	no	82.758	85.681	PhosphoSitePlus;EPSD	TCGA;COSMIC	72.838	Up-regulation
CMGC_GSK_GSK3A_ST	P35222	CTNNB1	P49840	GSK3A	S37	T41I	41	Missense	distal	4	no	82.758	79.185	PhosphoSitePlus;EPSD	TCGA;COSMIC	72.838	Down-regulation
CMGC_GSK_GSK3A_ST	P35222	CTNNB1	P49840	GSK3A	S37	S33A	33	Missense	distal	-4	no	82.758	77.811	PhosphoSitePlus;EPSD	TCGA;COSMIC	72.838	Down-regulation
CMGC_GSK_GSK3A_ST	P35222	CTNNB1	P49840	GSK3A	S37	S33Y	33	Missense	distal	-4	no	82.758	81.877	PhosphoSitePlus;EPSD	TCGA;COSMIC;GDSC;CCLE	72.838	Down-regulation
CMGC_GSK_GSK3A_ST	P35222	CTNNB1	P49840	GSK3A	S37	D32V	32	Missense	distal	-5	no	82.758	85.080	PhosphoSitePlus;EPSD	TCGA;COSMIC;CCLE	72.838	Up-regulation
CMGC_GSK_GSK3A_ST	P35222	CTNNB1	P49840	GSK3A	S37	S33P	33	Missense	distal	-4	no	82.758	79.172	PhosphoSitePlus;EPSD	TCGA;COSMIC;CCLE	72.838	Down-regulation
CMGC_GSK_GSK3A_ST	P35222	CTNNB1	P49840	GSK3A	S37	H36P	36	Missense	proximal	-1	no	82.758	83.505	PhosphoSitePlus;EPSD	TCGA;COSMIC;CCLE	72.838	Up-regulation
CMGC_GSK_GSK3A_ST	P35222	CTNNB1	P49840	GSK3A	S37	D32Y	32	Missense	distal	-5	no	82.758	84.700	PhosphoSitePlus;EPSD	TCGA;COSMIC;CCLE	72.838	Up-regulation
CMGC_GSK_GSK3A_ST	P35222	CTNNB1	P49840	GSK3A	S37	I35S	35	Missense	proximal	-2	no	82.758	83.642	PhosphoSitePlus;EPSD	TCGA;COSMIC	72.838	Up-regulation
CMGC_GSK_GSK3A_ST	P35222	CTNNB1	P49840	GSK3A	S37	S37Y	37	Missense	central	0	yes	82.758	0.000	PhosphoSitePlus;EPSD	TCGA;COSMIC	72.838	Loss
CMGC_GSK_GSK3A_ST	P35222	CTNNB1	P49840	GSK3A	S37	S33C	33	Missense	distal	-4	no	82.758	58.680	PhosphoSitePlus;EPSD	TCGA;COSMIC;GDSC;CCLE	72.838	Loss
CMGC_GSK_GSK3A_ST	P35222	CTNNB1	P49840	GSK3A	S37	S37A	37	Missense	central	0	yes	82.758	0.000	PhosphoSitePlus;EPSD	TCGA;COSMIC;GDSC;CCLE	72.838	Loss
CMGC_GSK_GSK3A_ST	P35222	CTNNB1	P49840	GSK3A	S37	D32N	32	Missense	distal	-5	no	82.758	85.223	PhosphoSitePlus;EPSD	TCGA;COSMIC;CCLE	72.838	Up-regulation
CMGC_GSK_GSK3A_ST	P35222	CTNNB1	P49840	GSK3A	S37	S33T	33	Missense	distal	-4	no	82.758	83.567	PhosphoSitePlus;EPSD	TCGA;COSMIC	72.838	Up-regulation
CMGC_GSK_GSK3A_ST	P35222	CTNNB1	P49840	GSK3A	S37	T41N	41	Missense	distal	4	no	82.758	76.869	PhosphoSitePlus;EPSD	TCGA;COSMIC	72.838	Down-regulation
CMGC_GSK_GSK3A_ST	P35222	CTNNB1	P49840	GSK3A	S37	S37P	37	Missense	central	0	yes	82.758	0.000	PhosphoSitePlus;EPSD	TCGA;COSMIC;GDSC;CCLE	72.838	Loss
CMGC_GSK_GSK3A_ST	P35222	CTNNB1	P49840	GSK3A	S37	D32A	32	Missense	distal	-5	no	82.758	86.267	PhosphoSitePlus;EPSD	TCGA;COSMIC	72.838	Up-regulation
CMGC_GSK_GSK3A_ST	P35222	CTNNB1	P49840	GSK3A	T41	S45F	45	Missense	distal	4	no	88.151	65.860	EPSD;PhosphoSitePlus	TCGA;COSMIC;GDSC;CCLE	72.838	Loss
CMGC_GSK_GSK3A_ST	P35222	CTNNB1	P49840	GSK3A	T41	G34R	34	Missense	distal	-7	no	88.151	87.050	EPSD;PhosphoSitePlus	TCGA;COSMIC	72.838	Down-regulation
CMGC_GSK_GSK3A_ST	P35222	CTNNB1	P49840	GSK3A	T41	S45P	45	Missense	distal	4	no	88.151	82.165	EPSD;PhosphoSitePlus	TCGA;COSMIC;CCLE	72.838	Down-regulation
CMGC_GSK_GSK3A_ST	P35222	CTNNB1	P49840	GSK3A	T41	G34V	34	Missense	distal	-7	no	88.151	88.041	EPSD;PhosphoSitePlus	TCGA;COSMIC;CCLE	72.838	Down-regulation
CMGC_GSK_GSK3A_ST	P35222	CTNNB1	P49840	GSK3A	T41	T41A	41	Missense	central	0	yes	88.151	0.000	EPSD;PhosphoSitePlus	TCGA;COSMIC;GDSC;CCLE	72.838	Loss
CMGC_GSK_GSK3A_ST	P35222	CTNNB1	P49840	GSK3A	T41	G34E	34	Missense	distal	-7	no	88.151	88.033	EPSD;PhosphoSitePlus	TCGA;COSMIC;GDSC;CCLE	72.838	Down-regulation
CMGC_GSK_GSK3A_ST	P35222	CTNNB1	P49840	GSK3A	T41	S37C	37	Missense	distal	-4	no	88.151	64.073	EPSD;PhosphoSitePlus	TCGA;COSMIC;GDSC;CCLE	72.838	Loss
CMGC_GSK_GSK3A_ST	P35222	CTNNB1	P49840	GSK3A	T41	S37F	37	Missense	distal	-4	no	88.151	80.392	EPSD;PhosphoSitePlus	TCGA;COSMIC;GDSC;CCLE	72.838	Down-regulation
CMGC_GSK_GSK3A_ST	P35222	CTNNB1	P49840	GSK3A	T41	T41I	41	Missense	central	0	yes	88.151	0.000	EPSD;PhosphoSitePlus	TCGA;COSMIC	72.838	Loss
CMGC_GSK_GSK3A_ST	P35222	CTNNB1	P49840	GSK3A	T41	S45Y	45	Missense	distal	4	no	88.151	82.527	EPSD;PhosphoSitePlus	TCGA;COSMIC	72.838	Down-regulation
CMGC_GSK_GSK3A_ST	P35222	CTNNB1	P49840	GSK3A	T41	H36P	36	Missense	distal	-5	no	88.151	89.537	EPSD;PhosphoSitePlus	TCGA;COSMIC;CCLE	72.838	Up-regulation
CMGC_GSK_GSK3A_ST	P35222	CTNNB1	P49840	GSK3A	T41	I35S	35	Missense	distal	-6	no	88.151	87.564	EPSD;PhosphoSitePlus	TCGA;COSMIC	72.838	Down-regulation
CMGC_GSK_GSK3A_ST	P35222	CTNNB1	P49840	GSK3A	T41	S37Y	37	Missense	distal	-4	no	88.151	87.270	EPSD;PhosphoSitePlus	TCGA;COSMIC	72.838	Down-regulation
CMGC_GSK_GSK3A_ST	P35222	CTNNB1	P49840	GSK3A	T41	S37A	37	Missense	distal	-4	no	88.151	83.204	EPSD;PhosphoSitePlus	TCGA;COSMIC;GDSC;CCLE	72.838	Down-regulation
CMGC_GSK_GSK3A_ST	P35222	CTNNB1	P49840	GSK3A	T41	T41N	41	Missense	central	0	yes	88.151	0.000	EPSD;PhosphoSitePlus	TCGA;COSMIC	72.838	Loss
CMGC_GSK_GSK3A_ST	P35222	CTNNB1	P49840	GSK3A	T41	S45C	45	Missense	distal	4	no	88.151	14.737	EPSD;PhosphoSitePlus	TCGA;COSMIC;GDSC;CCLE	72.838	Loss
CMGC_GSK_GSK3A_ST	P35222	CTNNB1	P49840	GSK3A	T41	S37P	37	Missense	distal	-4	no	88.151	84.564	EPSD;PhosphoSitePlus	TCGA;COSMIC;GDSC;CCLE	72.838	Down-regulation
CMGC_GSK_GSK3A_ST	P35222	CTNNB1	P49840	GSK3A	S45	S45F	45	Missense	central	0	yes	90.132	0.000	EPSD	TCGA;COSMIC;GDSC;CCLE	72.838	Loss
CMGC_GSK_GSK3A_ST	P35222	CTNNB1	P49840	GSK3A	S45	S45P	45	Missense	central	0	yes	90.132	0.000	EPSD	TCGA;COSMIC;CCLE	72.838	Loss
CMGC_GSK_GSK3A_ST	P35222	CTNNB1	P49840	GSK3A	S45	T41A	41	Missense	distal	-4	no	90.132	84.376	EPSD	TCGA;COSMIC;GDSC;CCLE	72.838	Down-regulation
CMGC_GSK_GSK3A_ST	P35222	CTNNB1	P49840	GSK3A	S45	T41I	41	Missense	distal	-4	no	90.132	83.538	EPSD	TCGA;COSMIC	72.838	Down-regulation
CMGC_GSK_GSK3A_ST	P35222	CTNNB1	P49840	GSK3A	S45	S45Y	45	Missense	central	0	yes	90.132	0.000	EPSD	TCGA;COSMIC	72.838	Loss
CMGC_GSK_GSK3A_ST	P35222	CTNNB1	P49840	GSK3A	S45	T41N	41	Missense	distal	-4	no	90.132	86.750	EPSD	TCGA;COSMIC	72.838	Down-regulation
CMGC_GSK_GSK3A_ST	P35222	CTNNB1	P49840	GSK3A	S45	S45C	45	Missense	central	0	yes	90.132	0.000	EPSD	TCGA;COSMIC;GDSC;CCLE	72.838	Loss
CMGC_GSK_GSK3A_ST	P35222	CTNNB1	P49840	GSK3A	S47	T41A	41	Missense	distal	-6	no	72.524	73.107	EPSD	TCGA;COSMIC;GDSC;CCLE	72.838	Gain
CMGC_GSK_GSK3A_ST	P35222	CTNNB1	P49840	GSK3A	S47	T41I	41	Missense	distal	-6	no	72.524	72.984	EPSD	TCGA;COSMIC	72.838	Gain
CMGC_GSK_GSK3A_ST	P35222	CTNNB1	P49840	GSK3A	S47	T41N	41	Missense	distal	-6	no	72.524	72.985	EPSD	TCGA;COSMIC	72.838	Gain
CMGC_GSK_GSK3A_ST	P35222	CTNNB1	P49840	GSK3A	S179	R185G	185	Missense	distal	6	no	75.198	72.839	EPSD	TCGA;COSMIC	72.838	Down-regulation
CMGC_GSK_GSK3A_ST	P35222	CTNNB1	P49840	GSK3A	T547	R542H	542	Missense	distal	-5	no	77.744	77.945	EPSD	TCGA;COSMIC	72.838	Up-regulation
CMGC_GSK_GSK3A_ST	P35222	CTNNB1	P49840	GSK3A	T547	M553V	553	Missense	distal	6	no	77.744	74.798	EPSD	TCGA;COSMIC	72.838	Down-regulation
CMGC_GSK_GSK3A_ST	P35222	CTNNB1	P49840	GSK3A	T547	V541A	541	Missense	distal	-6	no	77.744	77.420	EPSD	TCGA;COSMIC	72.838	Down-regulation
CMGC_GSK_GSK3A_ST	P35222	CTNNB1	P49840	GSK3A	T653	S646C	646	Missense	distal	-7	no	74.760	73.181	EPSD	TCGA;COSMIC	72.838	Down-regulation
CMGC_GSK_GSK3A_ST	P35222	CTNNB1	P49840	GSK3A	T653	E649Q	649	Missense	distal	-4	no	74.760	70.009	EPSD	TCGA;COSMIC	72.838	Loss
CMGC_GSK_GSK3A_ST	P35222	CTNNB1	P49840	GSK3A	T653	T653K	653	Missense	central	0	yes	74.760	0.000	EPSD	TCGA;COSMIC	72.838	Loss
CMGC_GSK_GSK3A_ST	Q9Y6Q9	NCOA3	P49840	GSK3A	S413	P412A	412	Missense	proximal	-1	no	73.868	73.744	EPSD	TCGA;ICGC;COSMIC	72.838	Down-regulation
CMGC_GSK_GSK3A_ST	Q9Y6Q9	NCOA3	P49840	GSK3A	S413	S413N	413	Missense	central	0	yes	73.868	0.000	EPSD	TCGA;COSMIC	72.838	Loss
CMGC_GSK_GSK3A_ST	Q9Y6Q9	NCOA3	P49840	GSK3A	T425	S429R	429	Missense	distal	4	no	81.714	72.319	EPSD	TCGA;ICGC;COSMIC	72.838	Loss
CMGC_GSK_GSK3A_ST	Q9Y6Q9	NCOA3	P49840	GSK3A	S429	S429R	429	Missense	central	0	yes	77.632	0.000	EPSD	TCGA;ICGC;COSMIC	72.838	Loss
CMGC_GSK_GSK3A_ST	Q9Y6Q9	NCOA3	P49840	GSK3A	S450	S453F	453	Missense	distal	3	no	78.726	75.359	EPSD	TCGA;ICGC;COSMIC	72.838	Down-regulation
CMGC_GSK_GSK3A_ST	Q9Y6Q9	NCOA3	P49840	GSK3A	S450	M448T	448	Missense	proximal	-2	no	78.726	79.190	EPSD	TCGA;ICGC;COSMIC	72.838	Up-regulation
CMGC_GSK_GSK3A_ST	Q9Y6Q9	NCOA3	P49840	GSK3A	S450	S450P	450	Missense	central	0	yes	78.726	0.000	EPSD	TCGA;COSMIC	72.838	Loss
CMGC_GSK_GSK3A_ST	Q9Y6Q9	NCOA3	P49840	GSK3A	S453	N458T	458	Missense	distal	5	no	53.154	75.598	EPSD	TCGA;COSMIC	72.838	Gain
CMGC_GSK_GSK3A_ST	Q9Y6Q9	NCOA3	P49840	GSK3A	S465	N458T	458	Missense	distal	-7	no	78.023	78.588	EPSD	TCGA;COSMIC	72.838	Up-regulation
CMGC_GSK_GSK3A_ST	Q9Y6Q9	NCOA3	P49840	GSK3A	S470	L473F	473	Missense	distal	3	no	88.413	87.573	EPSD	TCGA;COSMIC	72.838	Down-regulation
CMGC_GSK_GSK3A_ST	Q9Y6Q9	NCOA3	P49840	GSK3A	S505	P499A	499	Missense	distal	-6	no	80.489	81.144	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	72.838	Up-regulation
CMGC_GSK_GSK3A_ST	Q9Y6Q9	NCOA3	P49840	GSK3A	S505	G511D	511	Missense	distal	6	no	80.489	81.204	EPSD;PhosphoSitePlus	TCGA	72.838	Up-regulation
CMGC_GSK_GSK3A_ST	Q9Y6Q9	NCOA3	P49840	GSK3A	S509	G511D	511	Missense	proximal	2	no	82.392	80.527	PhosphoSitePlus;EPSD	TCGA	72.838	Down-regulation
CMGC_GSK_GSK3A_ST	Q9Y6Q9	NCOA3	P49840	GSK3A	S543	S542L	542	Missense	proximal	-1	no	82.446	82.188	EPSD	TCGA;ICGC;COSMIC	72.838	Down-regulation
CMGC_GSK_GSK3A_ST	Q9Y6Q9	NCOA3	P49840	GSK3A	S543	S536F	536	Missense	distal	-7	no	82.446	79.367	EPSD	TCGA;ICGC;COSMIC	72.838	Down-regulation
CMGC_GSK_GSK3A_ST	Q9Y6Q9	NCOA3	P49840	GSK3A	S543	S539F	539	Missense	distal	-4	no	82.446	74.687	EPSD	TCGA;ICGC;COSMIC	72.838	Down-regulation
CMGC_GSK_GSK3A_ST	Q9Y6Q9	NCOA3	P49840	GSK3A	S602	A606S	606	Missense	distal	4	no	70.610	73.695	EPSD	TCGA;ICGC;COSMIC	72.838	Gain
CMGC_GSK_GSK3A_ST	Q9Y6Q9	NCOA3	P49840	GSK3A	S640	K647R	647	Missense	distal	7	no	93.688	92.529	EPSD	TCGA;ICGC;COSMIC	72.838	Down-regulation
CMGC_GSK_GSK3A_ST	Q9Y6Q9	NCOA3	P49840	GSK3A	S640	S644L	644	Missense	distal	4	no	93.688	88.279	EPSD	TCGA;COSMIC	72.838	Down-regulation
CMGC_GSK_GSK3A_ST	Q9Y6Q9	NCOA3	P49840	GSK3A	S655	S662C	662	Missense	distal	7	no	84.747	83.934	EPSD	TCGA;COSMIC	72.838	Down-regulation
CMGC_GSK_GSK3A_ST	Q9Y6Q9	NCOA3	P49840	GSK3A	S660	S662C	662	Missense	proximal	2	no	75.606	72.859	EPSD	TCGA;COSMIC	72.838	Down-regulation
CMGC_GSK_GSK3A_ST	Q9Y6Q9	NCOA3	P49840	GSK3A	S664	S662C	662	Missense	proximal	-2	no	83.601	82.460	EPSD	TCGA;COSMIC	72.838	Down-regulation
CMGC_GSK_GSK3A_ST	Q9Y6Q9	NCOA3	P49840	GSK3A	S664	S671C	671	Missense	distal	7	no	83.601	82.788	EPSD	TCGA;COSMIC	72.838	Down-regulation
CMGC_GSK_GSK3A_ST	Q9Y6Q9	NCOA3	P49840	GSK3A	S664	S669C	669	Missense	distal	5	no	83.601	70.319	EPSD	TCGA;ICGC;COSMIC	72.838	Loss
CMGC_GSK_GSK3A_ST	Q9Y6Q9	NCOA3	P49840	GSK3A	S694	G692E	692	Missense	proximal	-2	no	83.545	83.800	EPSD	TCGA;ICGC;COSMIC	72.838	Up-regulation
CMGC_GSK_GSK3A_ST	Q9Y6Q9	NCOA3	P49840	GSK3A	T702	D709Y	709	Missense	distal	7	no	72.140	73.566	EPSD	TCGA;COSMIC	72.838	Gain
CMGC_GSK_GSK3A_ST	Q9Y6Q9	NCOA3	P49840	GSK3A	T706	D709Y	709	Missense	distal	3	no	71.907	73.932	EPSD	TCGA;COSMIC	72.838	Gain
CMGC_GSK_GSK3A_ST	Q9Y6Q9	NCOA3	P49840	GSK3A	S728	Q724H	724	Missense	distal	-4	no	86.863	92.881	EPSD	TCGA;COSMIC	72.838	Up-regulation
CMGC_GSK_GSK3A_ST	Q9Y6Q9	NCOA3	P49840	GSK3A	S728	V721A	721	Missense	distal	-7	no	86.863	87.738	EPSD	TCGA	72.838	Up-regulation
CMGC_GSK_GSK3A_ST	Q9Y6Q9	NCOA3	P49840	GSK3A	S767	I774S	774	Missense	distal	7	no	80.745	80.851	EPSD	TCGA;ICGC;COSMIC	72.838	Up-regulation
CMGC_GSK_GSK3A_ST	Q9Y6Q9	NCOA3	P49840	GSK3A	T770	I774S	774	Missense	distal	4	no	74.232	78.305	EPSD	TCGA;ICGC;COSMIC	72.838	Up-regulation
CMGC_GSK_GSK3A_ST	Q9Y6Q9	NCOA3	P49840	GSK3A	S777	I774S	774	Missense	distal	-3	no	74.236	76.453	EPSD	TCGA;ICGC;COSMIC	72.838	Up-regulation
CMGC_GSK_GSK3A_ST	Q9Y6Q9	NCOA3	P49840	GSK3A	S778	I774S	774	Missense	distal	-4	no	78.542	84.326	EPSD	TCGA;ICGC;COSMIC	72.838	Up-regulation
CMGC_GSK_GSK3A_ST	Q9Y6Q9	NCOA3	P49840	GSK3A	S860	S867G	867	Missense	distal	7	no	78.889	78.975	EPSD	TCGA;ICGC;COSMIC	72.838	Up-regulation
CMGC_GSK_GSK3A_ST	Q9Y6Q9	NCOA3	P49840	GSK3A	S860	R854Q	854	Missense	distal	-6	no	78.889	78.547	EPSD	TCGA;ICGC;COSMIC	72.838	Down-regulation
CMGC_GSK_GSK3A_ST	Q9Y6Q9	NCOA3	P49840	GSK3A	S863	S867G	867	Missense	distal	4	no	76.591	59.054	EPSD	TCGA;ICGC;COSMIC	72.838	Loss
CMGC_GSK_GSK3A_ST	Q9Y6Q9	NCOA3	P49840	GSK3A	S863	P868S	868	Missense	distal	5	no	76.591	71.034	EPSD	TCGA;ICGC;COSMIC	72.838	Loss
CMGC_GSK_GSK3A_ST	Q9Y6Q9	NCOA3	P49840	GSK3A	S863	P868L	868	Missense	distal	5	no	76.591	67.418	EPSD	TCGA;ICGC;COSMIC	72.838	Loss
CMGC_GSK_GSK3A_ST	Q9Y6Q9	NCOA3	P49840	GSK3A	T912	P915S	915	Missense	distal	3	no	72.944	71.612	EPSD	TCGA;ICGC;COSMIC	72.838	Loss
CMGC_GSK_GSK3A_ST	Q9Y6Q9	NCOA3	P49840	GSK3A	T912	R907Q	907	Missense	distal	-5	no	72.944	75.294	EPSD	TCGA;ICGC;COSMIC	72.838	Up-regulation
CMGC_GSK_GSK3A_ST	Q9Y6Q9	NCOA3	P49840	GSK3A	S1330	S1337L	1337	Missense	distal	7	no	83.229	82.607	EPSD	TCGA;COSMIC;GDSC;CCLE	72.838	Down-regulation
CMGC_GSK_GSK3A_ST	Q92597	NDRG1	P49840	GSK3A	T47	L40V	40	Missense	distal	-7	no	71.174	72.934	EPSD	TCGA;ICGC;COSMIC	72.838	Gain
CMGC_GSK_GSK3A_ST	Q92597	NDRG1	P49840	GSK3A	T321	R327C	327	Missense	distal	6	no	77.377	73.214	EPSD	TCGA;COSMIC	72.838	Down-regulation
CMGC_GSK_GSK3A_ST	Q92597	NDRG1	P49840	GSK3A	S326	R327C	327	Missense	proximal	1	no	76.030	57.641	EPSD	TCGA;COSMIC	72.838	Loss
CMGC_GSK_GSK3A_ST	Q92597	NDRG1	P49840	GSK3A	S336	S336C	336	Missense	central	0	yes	77.323	0.000	EPSD	TCGA	72.838	Loss
CMGC_GSK_GSK3A_ST	Q92597	NDRG1	P49840	GSK3A	S336	R343C	343	Missense	distal	7	no	77.323	77.046	EPSD	TCGA;COSMIC	72.838	Down-regulation
CMGC_GSK_GSK3A_ST	Q92597	NDRG1	P49840	GSK3A	S336	R341L	341	Missense	distal	5	no	77.323	73.294	EPSD	TCGA;COSMIC	72.838	Down-regulation
CMGC_GSK_GSK3A_ST	Q92597	NDRG1	P49840	GSK3A	S336	R343H	343	Missense	distal	7	no	77.323	77.796	EPSD	TCGA	72.838	Up-regulation
CMGC_GSK_GSK3A_ST	Q92597	NDRG1	P49840	GSK3A	T340	S336C	336	Missense	distal	-4	no	85.400	61.322	EPSD	TCGA	72.838	Loss
CMGC_GSK_GSK3A_ST	Q92597	NDRG1	P49840	GSK3A	T340	R343C	343	Missense	distal	3	no	85.400	80.800	EPSD	TCGA;COSMIC	72.838	Down-regulation
CMGC_GSK_GSK3A_ST	Q92597	NDRG1	P49840	GSK3A	T340	R341L	341	Missense	proximal	1	no	85.400	80.001	EPSD	TCGA;COSMIC	72.838	Down-regulation
CMGC_GSK_GSK3A_ST	Q92597	NDRG1	P49840	GSK3A	T340	R343H	343	Missense	distal	3	no	85.400	89.411	EPSD	TCGA	72.838	Up-regulation
CMGC_GSK_GSK3A_ST	Q92597	NDRG1	P49840	GSK3A	S342	S336C	336	Missense	distal	-6	no	87.523	88.119	PhosphoSitePlus;EPSD	TCGA	72.838	Up-regulation
CMGC_GSK_GSK3A_ST	Q92597	NDRG1	P49840	GSK3A	S342	R343C	343	Missense	proximal	1	no	87.523	69.134	PhosphoSitePlus;EPSD	TCGA;COSMIC	72.838	Loss
CMGC_GSK_GSK3A_ST	Q92597	NDRG1	P49840	GSK3A	S342	R341L	341	Missense	proximal	-1	no	87.523	87.563	PhosphoSitePlus;EPSD	TCGA;COSMIC	72.838	Up-regulation
CMGC_GSK_GSK3A_ST	Q92597	NDRG1	P49840	GSK3A	S342	R343H	343	Missense	proximal	1	no	87.523	69.762	PhosphoSitePlus;EPSD	TCGA	72.838	Loss
CMGC_GSK_GSK3A_ST	Q92597	NDRG1	P49840	GSK3A	T346	R343H	343	Missense	distal	-3	no	72.803	73.532	EPSD	TCGA	72.838	Gain
CMGC_GSK_GSK3A_ST	Q92597	NDRG1	P49840	GSK3A	T350	R343C	343	Missense	distal	-7	no	81.847	81.174	EPSD	TCGA;COSMIC	72.838	Down-regulation
CMGC_GSK_GSK3A_ST	Q92597	NDRG1	P49840	GSK3A	T350	T350P	350	Missense	central	0	yes	81.847	0.000	EPSD	TCGA;COSMIC	72.838	Loss
CMGC_GSK_GSK3A_ST	Q92597	NDRG1	P49840	GSK3A	T350	R343H	343	Missense	distal	-7	no	81.847	83.914	EPSD	TCGA	72.838	Up-regulation
CMGC_GSK_GSK3A_ST	Q92597	NDRG1	P49840	GSK3A	T350	R351Q	351	Missense	proximal	1	no	81.847	79.823	EPSD	TCGA;COSMIC;CCLE	72.838	Down-regulation
CMGC_GSK_GSK3A_ST	Q92597	NDRG1	P49840	GSK3A	S352	T350P	350	Missense	proximal	-2	no	90.406	90.974	EPSD;PhosphoSitePlus	TCGA;COSMIC	72.838	Up-regulation
CMGC_GSK_GSK3A_ST	Q92597	NDRG1	P49840	GSK3A	S352	E358K	358	Missense	distal	6	no	90.406	90.951	EPSD;PhosphoSitePlus	TCGA;COSMIC	72.838	Up-regulation
CMGC_GSK_GSK3A_ST	Q92597	NDRG1	P49840	GSK3A	S352	R351Q	351	Missense	proximal	-1	no	90.406	91.579	EPSD;PhosphoSitePlus	TCGA;COSMIC;CCLE	72.838	Up-regulation
CMGC_GSK_GSK3A_ST	Q92597	NDRG1	P49840	GSK3A	T356	T350P	350	Missense	distal	-6	no	82.016	81.943	EPSD	TCGA;COSMIC	72.838	Down-regulation
CMGC_GSK_GSK3A_ST	Q92597	NDRG1	P49840	GSK3A	T356	E358K	358	Missense	proximal	2	no	82.016	82.938	EPSD	TCGA;COSMIC	72.838	Up-regulation
CMGC_GSK_GSK3A_ST	Q92597	NDRG1	P49840	GSK3A	T356	R351Q	351	Missense	distal	-5	no	82.016	84.365	EPSD	TCGA;COSMIC;CCLE	72.838	Up-regulation
CMGC_GSK_GSK3A_ST	Q92597	NDRG1	P49840	GSK3A	T356	S362R	362	Missense	distal	6	no	82.016	83.421	EPSD	TCGA;COSMIC	72.838	Up-regulation
CMGC_GSK_GSK3A_ST	Q92597	NDRG1	P49840	GSK3A	S357	T350P	350	Missense	distal	-7	no	74.964	74.270	EPSD	TCGA;COSMIC	72.838	Down-regulation
CMGC_GSK_GSK3A_ST	Q92597	NDRG1	P49840	GSK3A	S357	E358K	358	Missense	proximal	1	no	74.964	80.884	EPSD	TCGA;COSMIC	72.838	Up-regulation
CMGC_GSK_GSK3A_ST	Q92597	NDRG1	P49840	GSK3A	S357	R351Q	351	Missense	distal	-6	no	74.964	74.622	EPSD	TCGA;COSMIC;CCLE	72.838	Down-regulation
CMGC_GSK_GSK3A_ST	Q92597	NDRG1	P49840	GSK3A	S357	S362R	362	Missense	distal	5	no	74.964	75.376	EPSD	TCGA;COSMIC	72.838	Up-regulation
CMGC_GSK_GSK3A_ST	Q92597	NDRG1	P49840	GSK3A	T360	S367N	367	Missense	distal	7	no	78.647	77.998	EPSD	TCGA;COSMIC	72.838	Down-regulation
CMGC_GSK_GSK3A_ST	Q92597	NDRG1	P49840	GSK3A	T360	E358K	358	Missense	proximal	-2	no	78.647	80.009	EPSD	TCGA;COSMIC	72.838	Up-regulation
CMGC_GSK_GSK3A_ST	Q92597	NDRG1	P49840	GSK3A	T360	S362R	362	Missense	proximal	2	no	78.647	78.851	EPSD	TCGA;COSMIC	72.838	Up-regulation
CMGC_GSK_GSK3A_ST	Q92597	NDRG1	P49840	GSK3A	S362	S367N	367	Missense	distal	5	no	86.523	64.756	EPSD;PhosphoSitePlus	TCGA;COSMIC	72.838	Loss
CMGC_GSK_GSK3A_ST	Q92597	NDRG1	P49840	GSK3A	S362	E358K	358	Missense	distal	-4	no	86.523	84.729	EPSD;PhosphoSitePlus	TCGA;COSMIC	72.838	Down-regulation
CMGC_GSK_GSK3A_ST	Q92597	NDRG1	P49840	GSK3A	S362	S362R	362	Missense	central	0	yes	86.523	0.000	EPSD;PhosphoSitePlus	TCGA;COSMIC	72.838	Loss
CMGC_GSK_GSK3A_ST	P31749	AKT1	P49840	GSK3A	S122	E116K	116	Missense	distal	-6	no	77.174	77.380	EPSD	TCGA;ICGC;COSMIC	72.838	Up-regulation
CMGC_GSK_GSK3A_ST	P31749	AKT1	P49840	GSK3A	S122	R121W	121	Missense	proximal	-1	no	77.174	77.237	EPSD	TCGA;ICGC;COSMIC	72.838	Up-regulation
CMGC_GSK_GSK3A_ST	P31749	AKT1	P49840	GSK3A	S129	E132K	132	Missense	distal	3	no	76.993	77.498	EPSD	TCGA;COSMIC	72.838	Up-regulation
CMGC_GSK_GSK3A_ST	P31749	AKT1	P49840	GSK3A	S129	E133D	133	Missense	distal	4	no	76.993	76.611	EPSD	TCGA;ICGC;COSMIC	72.838	Down-regulation
CMGC_GSK_GSK3A_ST	P31749	AKT1	P49840	GSK3A	S129	A131T	131	Missense	proximal	2	no	76.993	78.669	EPSD	TCGA;ICGC;COSMIC	72.838	Up-regulation
CMGC_GSK_GSK3A_ST	P31749	AKT1	P49840	GSK3A	T312	G311D	311	Missense	proximal	-1	no	84.746	84.129	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC;GDSC;CCLE	72.838	Down-regulation
CMGC_GSK_GSK3A_ST	P31749	AKT1	P49840	GSK3A	S422	Y417C	417	Missense	distal	-5	no	74.281	73.089	EPSD	TCGA;ICGC;COSMIC	72.838	Down-regulation
CMGC_GSK_GSK3A_ST	P31749	AKT1	P49840	GSK3A	S422	P423T	423	Missense	proximal	1	no	74.281	59.630	EPSD	TCGA;ICGC	72.838	Loss
CMGC_GSK_GSK3A_ST	P31749	AKT1	P49840	GSK3A	S422	E418K	418	Missense	distal	-4	no	74.281	72.488	EPSD	TCGA;ICGC	72.838	Loss
CMGC_GSK_GSK3A_ST	P31749	AKT1	P49840	GSK3A	T443	I447V	447	Missense	distal	4	no	75.141	73.635	EPSD	TCGA;ICGC;COSMIC	72.838	Down-regulation
CMGC_GSK_GSK3A_ST	Q16584	MAP3K11	P49840	GSK3A	S35	G40S	40	Missense	distal	5	no	84.846	84.880	EPSD	TCGA;ICGC;COSMIC	72.838	Up-regulation
CMGC_GSK_GSK3A_ST	Q16584	MAP3K11	P49840	GSK3A	S419	K413N	413	Missense	distal	-6	no	82.735	83.501	EPSD	TCGA;ICGC;COSMIC	72.838	Up-regulation
CMGC_GSK_GSK3A_ST	Q16584	MAP3K11	P49840	GSK3A	S507	R514K	514	Missense	distal	7	no	83.004	84.163	EPSD	TCGA;ICGC;COSMIC	72.838	Up-regulation
CMGC_GSK_GSK3A_ST	Q16584	MAP3K11	P49840	GSK3A	S548	R550Q	550	Missense	proximal	2	no	74.857	74.259	EPSD	TCGA	72.838	Down-regulation
CMGC_GSK_GSK3A_ST	Q16584	MAP3K11	P49840	GSK3A	S548	S548F	548	Missense	central	0	yes	74.857	0.000	EPSD	TCGA;ICGC;COSMIC	72.838	Loss
CMGC_GSK_GSK3A_ST	Q16584	MAP3K11	P49840	GSK3A	S674	R669H	669	Missense	distal	-5	no	89.853	90.054	EPSD	TCGA;ICGC;COSMIC	72.838	Up-regulation
CMGC_GSK_GSK3A_ST	Q16584	MAP3K11	P49840	GSK3A	T677	A684T	684	Missense	distal	7	no	82.147	82.536	EPSD	TCGA;ICGC;COSMIC	72.838	Up-regulation
CMGC_GSK_GSK3A_ST	Q16584	MAP3K11	P49840	GSK3A	T680	P687L	687	Missense	distal	7	no	93.279	92.316	EPSD	TCGA;ICGC;COSMIC	72.838	Down-regulation
CMGC_GSK_GSK3A_ST	Q16584	MAP3K11	P49840	GSK3A	T680	A684T	684	Missense	distal	4	no	93.279	95.865	EPSD	TCGA;ICGC;COSMIC	72.838	Up-regulation
CMGC_GSK_GSK3A_ST	Q16584	MAP3K11	P49840	GSK3A	S705	P706L	706	Missense	proximal	1	no	79.758	65.706	EPSD	TCGA;ICGC;COSMIC	72.838	Loss
CMGC_GSK_GSK3A_ST	Q16584	MAP3K11	P49840	GSK3A	S705	D704N	704	Missense	proximal	-1	no	79.758	79.812	EPSD	TCGA	72.838	Up-regulation
CMGC_GSK_GSK3A_ST	Q16584	MAP3K11	P49840	GSK3A	T708	P706L	706	Missense	proximal	-2	no	82.975	82.108	EPSD	TCGA;ICGC;COSMIC	72.838	Down-regulation
CMGC_GSK_GSK3A_ST	Q16584	MAP3K11	P49840	GSK3A	T708	D704N	704	Missense	distal	-4	no	82.975	82.082	EPSD	TCGA	72.838	Down-regulation
CMGC_GSK_GSK3A_ST	Q16584	MAP3K11	P49840	GSK3A	T745	R747H	747	Missense	proximal	2	no	79.217	78.380	EPSD	TCGA;COSMIC	72.838	Down-regulation
CMGC_GSK_GSK3A_ST	Q16584	MAP3K11	P49840	GSK3A	T745	P743L	743	Missense	proximal	-2	no	79.217	78.349	EPSD	TCGA;COSMIC	72.838	Down-regulation
CMGC_GSK_GSK3A_ST	Q16584	MAP3K11	P49840	GSK3A	S746	R747H	747	Missense	proximal	1	no	83.571	65.810	EPSD	TCGA;COSMIC	72.838	Loss
CMGC_GSK_GSK3A_ST	Q16584	MAP3K11	P49840	GSK3A	S746	P743L	743	Missense	distal	-3	no	83.571	81.826	EPSD	TCGA;COSMIC	72.838	Down-regulation
CMGC_GSK_GSK3A_ST	Q16584	MAP3K11	P49840	GSK3A	S748	R747H	747	Missense	proximal	-1	no	82.960	83.408	EPSD	TCGA;COSMIC	72.838	Up-regulation
CMGC_GSK_GSK3A_ST	Q16584	MAP3K11	P49840	GSK3A	S748	P743L	743	Missense	distal	-5	no	82.960	81.396	EPSD	TCGA;COSMIC	72.838	Down-regulation
CMGC_GSK_GSK3A_ST	Q16584	MAP3K11	P49840	GSK3A	T752	R747H	747	Missense	distal	-5	no	83.041	83.242	EPSD	TCGA;COSMIC	72.838	Up-regulation
CMGC_GSK_GSK3A_ST	Q16584	MAP3K11	P49840	GSK3A	T752	R757H	757	Missense	distal	5	no	83.041	76.546	EPSD	TCGA;COSMIC	72.838	Down-regulation
CMGC_GSK_GSK3A_ST	Q16584	MAP3K11	P49840	GSK3A	T755	R757H	757	Missense	proximal	2	no	84.778	83.941	EPSD	TCGA;COSMIC	72.838	Down-regulation
CMGC_GSK_GSK3A_ST	Q16584	MAP3K11	P49840	GSK3A	S770	R773C	773	Missense	distal	3	no	87.604	83.004	EPSD	TCGA;ICGC;COSMIC	72.838	Down-regulation
CMGC_GSK_GSK3A_ST	Q16584	MAP3K11	P49840	GSK3A	S770	R768Q	768	Missense	proximal	-2	no	87.604	87.268	EPSD	TCGA	72.838	Down-regulation
CMGC_GSK_GSK3A_ST	Q16584	MAP3K11	P49840	GSK3A	S770	S770L	770	Missense	central	0	yes	87.604	0.000	EPSD	TCGA;COSMIC	72.838	Loss
CMGC_GSK_GSK3A_ST	Q16584	MAP3K11	P49840	GSK3A	S770	P771L	771	Missense	proximal	1	no	87.604	73.552	EPSD	TCGA;COSMIC	72.838	Down-regulation
CMGC_GSK_GSK3A_ST	Q16584	MAP3K11	P49840	GSK3A	S783	A784V	784	Missense	proximal	1	no	80.056	70.233	EPSD	TCGA;ICGC;COSMIC	72.838	Loss
CMGC_GSK_GSK3A_ST	Q16584	MAP3K11	P49840	GSK3A	S783	R787L	787	Missense	distal	4	no	80.056	84.042	EPSD	TCGA;COSMIC	72.838	Up-regulation
CMGC_GSK_GSK3A_ST	Q16584	MAP3K11	P49840	GSK3A	S783	P790L	790	Missense	distal	7	no	80.056	79.093	EPSD	TCGA;COSMIC	72.838	Down-regulation
CMGC_GSK_GSK3A_ST	Q16584	MAP3K11	P49840	GSK3A	S783	P778S	778	Missense	distal	-5	no	80.056	80.142	EPSD	TCGA;ICGC;COSMIC	72.838	Up-regulation
CMGC_GSK_GSK3A_ST	Q16584	MAP3K11	P49840	GSK3A	S789	A784V	784	Missense	distal	-5	no	103.622	102.436	PhosphoSitePlus;EPSD	TCGA;ICGC;COSMIC	72.838	Down-regulation
CMGC_GSK_GSK3A_ST	Q16584	MAP3K11	P49840	GSK3A	S789	R787L	787	Missense	proximal	-2	no	103.622	102.543	PhosphoSitePlus;EPSD	TCGA;COSMIC	72.838	Down-regulation
CMGC_GSK_GSK3A_ST	Q16584	MAP3K11	P49840	GSK3A	S789	P790L	790	Missense	proximal	1	no	103.622	89.570	PhosphoSitePlus;EPSD	TCGA;COSMIC	72.838	Down-regulation
CMGC_GSK_GSK3A_ST	Q16584	MAP3K11	P49840	GSK3A	S789	P792S	792	Missense	distal	3	no	103.622	102.289	PhosphoSitePlus;EPSD	TCGA	72.838	Down-regulation
CMGC_GSK_GSK3A_ST	Q16584	MAP3K11	P49840	GSK3A	S793	R787L	787	Missense	distal	-6	no	89.990	89.783	EPSD;PhosphoSitePlus	TCGA;COSMIC	72.838	Down-regulation
CMGC_GSK_GSK3A_ST	Q16584	MAP3K11	P49840	GSK3A	S793	P790L	790	Missense	distal	-3	no	89.990	88.245	EPSD;PhosphoSitePlus	TCGA;COSMIC	72.838	Down-regulation
CMGC_GSK_GSK3A_ST	Q16584	MAP3K11	P49840	GSK3A	S793	R800Q	800	Missense	distal	7	no	89.990	90.494	EPSD;PhosphoSitePlus	TCGA;COSMIC	72.838	Up-regulation
CMGC_GSK_GSK3A_ST	Q16584	MAP3K11	P49840	GSK3A	S793	P792S	792	Missense	proximal	-1	no	89.990	89.093	EPSD;PhosphoSitePlus	TCGA	72.838	Down-regulation
CMGC_GSK_GSK3A_ST	Q16584	MAP3K11	P49840	GSK3A	S815	D814E	814	Missense	proximal	-1	no	76.751	78.440	EPSD	TCGA;ICGC;COSMIC	72.838	Up-regulation
CMGC_GSK_GSK3A_ST	O75030	MITF	P49840	GSK3A	S55	S51F	51	Missense	distal	-4	no	75.212	67.454	EPSD	TCGA;ICGC;COSMIC	72.838	Loss
CMGC_GSK_GSK3A_ST	O75030	MITF	P49840	GSK3A	S55	R56H	56	Missense	proximal	1	no	75.212	57.451	EPSD	TCGA;ICGC;COSMIC;GDSC;CCLE	72.838	Loss
CMGC_GSK_GSK3A_ST	O75030	MITF	P49840	GSK3A	S55	S49R	49	Missense	distal	-6	no	75.212	75.600	EPSD	TCGA;ICGC;COSMIC	72.838	Up-regulation
CMGC_GSK_GSK3A_ST	O75030	MITF	P49840	GSK3A	S55	R60H	60	Missense	distal	5	no	75.212	68.717	EPSD	TCGA;ICGC;COSMIC	72.838	Loss
CMGC_GSK_GSK3A_ST	O75030	MITF	P49840	GSK3A	S55	M53L	53	Missense	proximal	-2	no	75.212	75.378	EPSD	TCGA;ICGC;COSMIC	72.838	Up-regulation
CMGC_GSK_GSK3A_ST	O75030	MITF	P49840	GSK3A	S55	R56C	56	Missense	proximal	1	no	75.212	56.823	EPSD	TCGA;ICGC;COSMIC	72.838	Loss
CMGC_GSK_GSK3A_ST	O75030	MITF	P49840	GSK3A	S176	A177T	177	Missense	proximal	1	no	73.322	72.337	EPSD	TCGA;ICGC;COSMIC	72.838	Loss
CMGC_GSK_GSK3A_ST	O75030	MITF	P49840	GSK3A	S176	V172L	172	Missense	distal	-4	no	73.322	72.825	EPSD	TCGA;ICGC;COSMIC	72.838	Loss
CMGC_GSK_GSK3A_ST	O75030	MITF	P49840	GSK3A	S176	P178L	178	Missense	proximal	2	no	73.322	72.612	EPSD	TCGA;ICGC;COSMIC	72.838	Loss
CMGC_GSK_GSK3A_ST	O75030	MITF	P49840	GSK3A	S176	P171L	171	Missense	distal	-5	no	73.322	71.758	EPSD	TCGA;ICGC;COSMIC;CCLE	72.838	Loss
CMGC_GSK_GSK3A_ST	O75030	MITF	P49840	GSK3A	S180	A177T	177	Missense	distal	-3	no	76.843	77.670	EPSD	TCGA;ICGC;COSMIC	72.838	Up-regulation
CMGC_GSK_GSK3A_ST	O75030	MITF	P49840	GSK3A	S180	T186M	186	Missense	distal	6	no	76.843	75.445	EPSD	TCGA;ICGC;COSMIC	72.838	Down-regulation
CMGC_GSK_GSK3A_ST	O75030	MITF	P49840	GSK3A	S180	P178L	178	Missense	proximal	-2	no	76.843	75.975	EPSD	TCGA;ICGC;COSMIC	72.838	Down-regulation
CMGC_GSK_GSK3A_ST	P24864	CCNE1	P49840	GSK3A	S103	R101K	101	Missense	proximal	-2	no	79.511	80.025	EPSD	TCGA;ICGC;COSMIC	72.838	Up-regulation
CMGC_GSK_GSK3A_ST	P24864	CCNE1	P49840	GSK3A	S381	R385T	385	Missense	distal	4	no	66.600	75.495	EPSD	TCGA;ICGC;COSMIC	72.838	Gain
CMGC_GSK_GSK3A_ST	P24864	CCNE1	P49840	GSK3A	S381	R385S	385	Missense	distal	4	no	66.600	75.995	EPSD	TCGA;ICGC;COSMIC	72.838	Gain
CMGC_GSK_GSK3A_ST	P24864	CCNE1	P49840	GSK3A	S387	R385T	385	Missense	proximal	-2	no	74.609	73.829	EPSD	TCGA;ICGC;COSMIC	72.838	Down-regulation
CMGC_GSK_GSK3A_ST	P24864	CCNE1	P49840	GSK3A	S387	R385S	385	Missense	proximal	-2	no	74.609	74.246	EPSD	TCGA;ICGC;COSMIC	72.838	Down-regulation
CMGC_GSK_GSK3A_ST	P24864	CCNE1	P49840	GSK3A	S387	A386S	386	Missense	proximal	-1	no	74.609	73.836	EPSD	TCGA;ICGC;COSMIC	72.838	Down-regulation
CMGC_GSK_GSK3A_ST	P24864	CCNE1	P49840	GSK3A	S391	R385T	385	Missense	distal	-6	no	89.096	88.836	EPSD	TCGA;ICGC;COSMIC	72.838	Down-regulation
CMGC_GSK_GSK3A_ST	P24864	CCNE1	P49840	GSK3A	S391	R385S	385	Missense	distal	-6	no	89.096	88.708	EPSD	TCGA;ICGC;COSMIC	72.838	Down-regulation
CMGC_GSK_GSK3A_ST	P24864	CCNE1	P49840	GSK3A	S391	A386S	386	Missense	distal	-5	no	89.096	88.695	EPSD	TCGA;ICGC;COSMIC	72.838	Down-regulation
CMGC_GSK_GSK3A_ST	P24864	CCNE1	P49840	GSK3A	S391	T395I	395	Missense	distal	4	no	89.096	85.523	EPSD	TCGA;ICGC;COSMIC	72.838	Down-regulation
CMGC_GSK_GSK3A_ST	P24864	CCNE1	P49840	GSK3A	S391	P396L	396	Missense	distal	5	no	89.096	79.923	EPSD	TCGA;ICGC;COSMIC	72.838	Down-regulation
CMGC_GSK_GSK3A_ST	P24864	CCNE1	P49840	GSK3A	T395	T395I	395	Missense	central	0	yes	86.429	0.000	PhosphoSitePlus	TCGA;ICGC;COSMIC	72.838	Loss
CMGC_GSK_GSK3A_ST	P24864	CCNE1	P49840	GSK3A	T395	P396L	396	Missense	proximal	1	no	86.429	72.377	PhosphoSitePlus	TCGA;ICGC;COSMIC	72.838	Loss
CMGC_GSK_GSK3A_ST	Q6R327	RICTOR	P49840	GSK3A	S265	T258S	258	Missense	distal	-7	no	76.825	75.977	EPSD	TCGA;ICGC;COSMIC	72.838	Down-regulation
CMGC_GSK_GSK3A_ST	Q6R327	RICTOR	P49840	GSK3A	T852	R855Q	855	Missense	distal	3	no	80.670	78.837	EPSD	TCGA;ICGC;GDSC	72.838	Down-regulation
CMGC_GSK_GSK3A_ST	Q6R327	RICTOR	P49840	GSK3A	T853	G860D	860	Missense	distal	7	no	73.267	71.830	EPSD	TCGA;ICGC;COSMIC	72.838	Loss
CMGC_GSK_GSK3A_ST	Q6R327	RICTOR	P49840	GSK3A	T853	R855Q	855	Missense	proximal	2	no	73.267	72.669	EPSD	TCGA;ICGC;GDSC	72.838	Loss
CMGC_GSK_GSK3A_ST	Q6R327	RICTOR	P49840	GSK3A	S1031	E1038G	1038	Missense	distal	7	no	85.403	85.010	EPSD	TCGA;ICGC;COSMIC	72.838	Down-regulation
CMGC_GSK_GSK3A_ST	Q6R327	RICTOR	P49840	GSK3A	S1035	S1042L	1042	Missense	distal	7	no	73.166	72.544	EPSD	TCGA;ICGC;COSMIC	72.838	Loss
CMGC_GSK_GSK3A_ST	Q6R327	RICTOR	P49840	GSK3A	S1035	E1038G	1038	Missense	distal	3	no	73.166	70.836	EPSD	TCGA;ICGC;COSMIC	72.838	Loss
CMGC_GSK_GSK3A_ST	Q6R327	RICTOR	P49840	GSK3A	S1039	S1042L	1042	Missense	distal	3	no	72.949	70.421	EPSD	TCGA;ICGC;COSMIC	72.838	Loss
CMGC_GSK_GSK3A_ST	Q6R327	RICTOR	P49840	GSK3A	S1039	E1038G	1038	Missense	proximal	-1	no	72.949	71.877	EPSD	TCGA;ICGC;COSMIC	72.838	Loss
CMGC_GSK_GSK3A_ST	Q6R327	RICTOR	P49840	GSK3A	S1121	G1117E	1117	Missense	distal	-4	no	73.112	76.279	EPSD	TCGA;ICGC;COSMIC	72.838	Up-regulation
CMGC_GSK_GSK3A_ST	Q6R327	RICTOR	P49840	GSK3A	S1121	L1120V	1120	Missense	proximal	-1	no	73.112	73.602	EPSD	TCGA;ICGC	72.838	Up-regulation
CMGC_GSK_GSK3A_ST	Q6R327	RICTOR	P49840	GSK3A	S1124	G1117E	1117	Missense	distal	-7	no	81.810	81.692	EPSD	TCGA;ICGC;COSMIC	72.838	Down-regulation
CMGC_GSK_GSK3A_ST	Q6R327	RICTOR	P49840	GSK3A	S1124	R1130Q	1130	Missense	distal	6	no	81.810	82.864	EPSD	TCGA;ICGC;COSMIC;GDSC;CCLE	72.838	Up-regulation
CMGC_GSK_GSK3A_ST	Q6R327	RICTOR	P49840	GSK3A	S1124	L1120V	1120	Missense	distal	-4	no	81.810	82.307	EPSD	TCGA;ICGC	72.838	Up-regulation
CMGC_GSK_GSK3A_ST	Q6R327	RICTOR	P49840	GSK3A	S1217	T1222I	1222	Missense	distal	5	no	73.728	62.296	EPSD	TCGA;ICGC;COSMIC	72.838	Loss
CMGC_GSK_GSK3A_ST	Q6R327	RICTOR	P49840	GSK3A	S1217	R1216H	1216	Missense	proximal	-1	no	73.728	74.177	EPSD	TCGA;ICGC;COSMIC;CCLE	72.838	Up-regulation
CMGC_GSK_GSK3A_ST	Q6R327	RICTOR	P49840	GSK3A	S1219	T1222I	1222	Missense	distal	3	no	82.371	79.647	EPSD	TCGA;ICGC;COSMIC	72.838	Down-regulation
CMGC_GSK_GSK3A_ST	Q6R327	RICTOR	P49840	GSK3A	S1219	R1216H	1216	Missense	distal	-3	no	82.371	83.100	EPSD	TCGA;ICGC;COSMIC;CCLE	72.838	Up-regulation
CMGC_GSK_GSK3A_ST	Q6R327	RICTOR	P49840	GSK3A	T1222	T1222I	1222	Missense	central	0	yes	75.301	0.000	EPSD	TCGA;ICGC;COSMIC	72.838	Loss
CMGC_GSK_GSK3A_ST	Q6R327	RICTOR	P49840	GSK3A	T1222	R1216H	1216	Missense	distal	-6	no	75.301	75.076	EPSD	TCGA;ICGC;COSMIC;CCLE	72.838	Down-regulation
CMGC_GSK_GSK3A_ST	Q6R327	RICTOR	P49840	GSK3A	T1226	T1222I	1222	Missense	distal	-4	no	75.950	69.356	EPSD	TCGA;ICGC;COSMIC	72.838	Loss
CMGC_GSK_GSK3A_ST	Q6R327	RICTOR	P49840	GSK3A	S1280	S1284L	1284	Missense	distal	4	no	75.233	69.823	EPSD	TCGA;ICGC;COSMIC	72.838	Loss
CMGC_GSK_GSK3A_ST	Q6R327	RICTOR	P49840	GSK3A	S1286	S1284L	1284	Missense	proximal	-2	no	83.909	83.193	EPSD	TCGA;ICGC;COSMIC	72.838	Down-regulation
CMGC_GSK_GSK3A_ST	Q6R327	RICTOR	P49840	GSK3A	S1292	R1299G	1299	Missense	distal	7	no	74.101	74.723	EPSD	TCGA;ICGC;COSMIC	72.838	Up-regulation
CMGC_GSK_GSK3A_ST	Q6R327	RICTOR	P49840	GSK3A	S1320	S1323R	1323	Missense	distal	3	no	91.495	91.781	EPSD	TCGA;ICGC;COSMIC	72.838	Up-regulation
CMGC_GSK_GSK3A_ST	Q6R327	RICTOR	P49840	GSK3A	S1320	D1316N	1316	Missense	distal	-4	no	91.495	90.601	EPSD	TCGA;ICGC	72.838	Down-regulation
CMGC_GSK_GSK3A_ST	Q6R327	RICTOR	P49840	GSK3A	S1323	S1323R	1323	Missense	central	0	yes	77.631	0.000	EPSD	TCGA;ICGC;COSMIC	72.838	Loss
CMGC_GSK_GSK3A_ST	Q6R327	RICTOR	P49840	GSK3A	S1323	D1316N	1316	Missense	distal	-7	no	77.631	79.330	EPSD	TCGA;ICGC	72.838	Up-regulation
CMGC_GSK_GSK3A_ST	Q6R327	RICTOR	P49840	GSK3A	S1353	P1354S	1354	Missense	proximal	1	no	76.756	61.064	EPSD	TCGA;ICGC;COSMIC	72.838	Loss
CMGC_GSK_GSK3A_ST	Q6R327	RICTOR	P49840	GSK3A	S1353	S1346C	1346	Missense	distal	-7	no	76.756	75.177	EPSD	TCGA;ICGC;COSMIC	72.838	Down-regulation
CMGC_GSK_GSK3A_ST	Q6R327	RICTOR	P49840	GSK3A	T1361	P1354S	1354	Missense	distal	-7	no	73.757	73.601	EPSD	TCGA;ICGC;COSMIC	72.838	Down-regulation
CMGC_GSK_GSK3A_ST	Q6R327	RICTOR	P49840	GSK3A	T1361	T1363I	1363	Missense	proximal	2	no	73.757	69.977	EPSD	TCGA;ICGC;COSMIC	72.838	Loss
CMGC_GSK_GSK3A_ST	Q6R327	RICTOR	P49840	GSK3A	S1373	S1378N	1378	Missense	distal	5	no	83.132	61.365	EPSD	TCGA;ICGC;COSMIC	72.838	Loss
CMGC_GSK_GSK3A_ST	Q6R327	RICTOR	P49840	GSK3A	S1407	S1407F	1407	Missense	central	0	yes	76.082	0.000	EPSD	TCGA;ICGC;COSMIC	72.838	Loss
CMGC_GSK_GSK3A_ST	Q6R327	RICTOR	P49840	GSK3A	S1407	R1405Q	1405	Missense	proximal	-2	no	76.082	75.747	EPSD	TCGA;ICGC;COSMIC	72.838	Down-regulation
CMGC_GSK_GSK3A_ST	Q6R327	RICTOR	P49840	GSK3A	S1414	S1407F	1407	Missense	distal	-7	no	76.953	73.875	EPSD	TCGA;ICGC;COSMIC	72.838	Down-regulation
CMGC_GSK_GSK3A_ST	Q6R327	RICTOR	P49840	GSK3A	S1414	G1420C	1420	Missense	distal	6	no	76.953	75.149	EPSD	TCGA;ICGC;COSMIC	72.838	Down-regulation
CMGC_GSK_GSK3A_ST	Q6R327	RICTOR	P49840	GSK3A	S1414	A1416V	1416	Missense	proximal	2	no	76.953	76.136	EPSD	TCGA;ICGC;COSMIC	72.838	Down-regulation
CMGC_GSK_GSK3A_ST	Q6R327	RICTOR	P49840	GSK3A	S1414	S1421P	1421	Missense	distal	7	no	76.953	77.295	EPSD	TCGA;ICGC;COSMIC	72.838	Up-regulation
CMGC_GSK_GSK3A_ST	Q6R327	RICTOR	P49840	GSK3A	S1581	S1585L	1585	Missense	distal	4	no	74.501	69.092	EPSD	TCGA;ICGC;COSMIC	72.838	Loss
CMGC_GSK_GSK3A_ST	Q6R327	RICTOR	P49840	GSK3A	S1581	S1588I	1588	Missense	distal	7	no	74.501	74.396	EPSD	TCGA;ICGC;COSMIC	72.838	Down-regulation
CMGC_GSK_GSK3A_ST	Q6R327	RICTOR	P49840	GSK3A	T1589	S1585L	1585	Missense	distal	-4	no	73.203	66.929	EPSD	TCGA;ICGC;COSMIC	72.838	Loss
CMGC_GSK_GSK3A_ST	Q6R327	RICTOR	P49840	GSK3A	T1589	S1588I	1588	Missense	proximal	-1	no	73.203	71.988	EPSD	TCGA;ICGC;COSMIC	72.838	Loss
CMGC_GSK_GSK3A_ST	Q6R327	RICTOR	P49840	GSK3A	T1695	E1690K	1690	Missense	distal	-5	no	74.247	74.137	PhosphoSitePlus	TCGA;COSMIC	72.838	Down-regulation
CMGC_GSK_GSK3A_ST	Q6R327	RICTOR	P49840	GSK3A	T1695	I1701T	1701	Missense	distal	6	no	74.247	76.675	PhosphoSitePlus	TCGA;COSMIC	72.838	Up-regulation
CMGC_GSK_GSK3A_ST	P01106	MYC	P49840	GSK3A	T58	E54D	54	Missense	distal	-4	no	93.334	93.325	PhosphoSitePlus	TCGA;ICGC;COSMIC;GDSC	72.838	Down-regulation
CMGC_GSK_GSK3A_ST	P01106	MYC	P49840	GSK3A	S159	S161L	161	Missense	proximal	2	no	72.973	72.952	EPSD	TCGA;ICGC;COSMIC	72.838	Down-regulation
CMGC_GSK_GSK3A_ST	P01106	MYC	P49840	GSK3A	S161	S161L	161	Missense	central	0	yes	75.825	0.000	EPSD	TCGA;ICGC;COSMIC	72.838	Loss
CMGC_GSK_GSK3A_ST	P01106	MYC	P49840	GSK3A	S344	K341R	341	Missense	distal	-3	no	82.425	82.823	EPSD	TCGA;ICGC;COSMIC	72.838	Up-regulation
CMGC_GSK_GSK3A_ST	P17812	CTPS1	P49840	GSK3A	T459	R454K	454	Missense	distal	-5	no	73.104	73.873	EPSD	TCGA;ICGC;COSMIC	72.838	Up-regulation
CMGC_GSK_GSK3A_ST	P17812	CTPS1	P49840	GSK3A	T459	F457L	457	Missense	proximal	-2	no	73.104	73.607	EPSD	TCGA;COSMIC	72.838	Up-regulation
CMGC_GSK_GSK3A_ST	P17812	CTPS1	P49840	GSK3A	S562	T566I	566	Missense	distal	4	no	85.728	82.155	EPSD	TCGA;ICGC;COSMIC	72.838	Down-regulation
CMGC_GSK_GSK3A_ST	P17812	CTPS1	P49840	GSK3A	S571	T566I	566	Missense	distal	-5	no	81.787	80.192	PhosphoSitePlus	TCGA;ICGC;COSMIC	72.838	Down-regulation
CMGC_GSK_GSK3A_ST	P17812	CTPS1	P49840	GSK3A	S571	P576H	576	Missense	distal	5	no	81.787	70.147	PhosphoSitePlus	TCGA;ICGC;COSMIC	72.838	Loss
CMGC_GSK_GSK3A_ST	Q9BYG3	NIFK	P49840	GSK3A	T220	T227N	227	Missense	distal	7	no	81.181	79.944	EPSD	TCGA;COSMIC	72.838	Down-regulation
CMGC_GSK_GSK3A_ST	Q9BYG3	NIFK	P49840	GSK3A	T223	T227N	227	Missense	distal	4	no	84.948	79.060	EPSD	TCGA;COSMIC	72.838	Down-regulation
CMGC_GSK_GSK3A_ST	Q9BYG3	NIFK	P49840	GSK3A	S230	G232D	232	Missense	proximal	2	no	82.284	80.419	PhosphoSitePlus;EPSD	TCGA;COSMIC	72.838	Down-regulation
CMGC_GSK_GSK3A_ST	Q9BYG3	NIFK	P49840	GSK3A	S230	T227N	227	Missense	distal	-3	no	82.284	80.290	PhosphoSitePlus;EPSD	TCGA;COSMIC	72.838	Down-regulation
CMGC_GSK_GSK3A_ST	Q9BYG3	NIFK	P49840	GSK3A	T234	G232D	232	Missense	proximal	-2	no	87.454	87.307	EPSD;PhosphoSitePlus	TCGA;COSMIC	72.838	Down-regulation
CMGC_GSK_GSK3A_ST	Q9BYG3	NIFK	P49840	GSK3A	T234	T227N	227	Missense	distal	-7	no	87.454	86.889	EPSD;PhosphoSitePlus	TCGA;COSMIC	72.838	Down-regulation
CMGC_GSK_GSK3A_ST	Q9BYG3	NIFK	P49840	GSK3A	T238	G232D	232	Missense	distal	-6	no	84.299	85.319	EPSD	TCGA;COSMIC	72.838	Up-regulation
CMGC_GSK_GSK3A_ST	Q9BYG3	NIFK	P49840	GSK3A	S247	D254N	254	Missense	distal	7	no	73.800	74.502	EPSD	TCGA;COSMIC	72.838	Up-regulation
CMGC_GSK_GSK3A_ST	Q9BYG3	NIFK	P49840	GSK3A	T279	E272V	272	Missense	distal	-7	no	91.695	91.703	EPSD	TCGA;COSMIC	72.838	Up-regulation
CMGC_GSK_GSK3A_ST	Q9BYG3	NIFK	P49840	GSK3A	T279	E276Q	276	Missense	distal	-3	no	91.695	90.439	EPSD	TCGA;COSMIC	72.838	Down-regulation
CMGC_GSK_GSK3A_ST	Q9BYG3	NIFK	P49840	GSK3A	T279	R284Q	284	Missense	distal	5	no	91.695	86.441	EPSD	TCGA;COSMIC	72.838	Down-regulation
CMGC_GSK_GSK3A_ST	Q13563	PKD2	P49840	GSK3A	S74	P78L	78	Missense	distal	4	no	83.979	84.555	EPSD	TCGA;ICGC;COSMIC	72.838	Up-regulation
CMGC_GSK_GSK3A_ST	Q13563	PKD2	P49840	GSK3A	S76	P78L	78	Missense	proximal	2	no	88.748	88.039	PhosphoSitePlus	TCGA;ICGC;COSMIC	72.838	Down-regulation
CMGC_GSK_GSK3A_ST	Q13563	PKD2	P49840	GSK3A	T260	S263F	263	Missense	distal	3	no	77.689	74.322	EPSD	TCGA;ICGC;COSMIC	72.838	Down-regulation
CMGC_GSK_GSK3A_ST	Q13563	PKD2	P49840	GSK3A	S263	S263F	263	Missense	central	0	yes	73.973	0.000	EPSD	TCGA;ICGC;COSMIC	72.838	Loss
CMGC_GSK_GSK3A_ST	Q13563	PKD2	P49840	GSK3A	S794	L791F	791	Missense	distal	-3	no	73.531	73.407	EPSD	TCGA;COSMIC	72.838	Down-regulation
CMGC_GSK_GSK3A_ST	Q13563	PKD2	P49840	GSK3A	S794	R798H	798	Missense	distal	4	no	73.531	54.889	EPSD	TCGA;COSMIC	72.838	Loss
CMGC_GSK_GSK3A_ST	Q13563	PKD2	P49840	GSK3A	S794	S795Y	795	Missense	proximal	1	no	73.531	81.614	EPSD	TCGA;COSMIC	72.838	Up-regulation
CMGC_GSK_GSK3A_ST	Q13563	PKD2	P49840	GSK3A	S802	R798H	798	Missense	distal	-4	no	73.096	76.060	EPSD	TCGA;COSMIC	72.838	Up-regulation
CMGC_GSK_GSK3A_ST	Q13563	PKD2	P49840	GSK3A	S802	S795Y	795	Missense	distal	-7	no	73.096	73.840	EPSD	TCGA;COSMIC	72.838	Up-regulation
CMGC_GSK_GSK3A_ST	Q13563	PKD2	P49840	GSK3A	S802	R803Q	803	Missense	proximal	1	no	73.096	71.072	EPSD	TCGA;COSMIC	72.838	Loss
CMGC_GSK_GSK3A_ST	Q13563	PKD2	P49840	GSK3A	S804	D810N	810	Missense	distal	6	no	75.424	77.017	EPSD	TCGA;COSMIC	72.838	Up-regulation
CMGC_GSK_GSK3A_ST	Q13563	PKD2	P49840	GSK3A	S804	R798H	798	Missense	distal	-6	no	75.424	75.200	EPSD	TCGA;COSMIC	72.838	Down-regulation
CMGC_GSK_GSK3A_ST	Q13563	PKD2	P49840	GSK3A	S804	R803Q	803	Missense	proximal	-1	no	75.424	76.598	EPSD	TCGA;COSMIC	72.838	Up-regulation
CMGC_GSK_GSK3A_ST	Q13563	PKD2	P49840	GSK3A	S808	D810N	810	Missense	proximal	2	no	78.504	79.240	EPSD	TCGA;COSMIC	72.838	Up-regulation
CMGC_GSK_GSK3A_ST	Q13563	PKD2	P49840	GSK3A	S808	S812F	812	Missense	distal	4	no	78.504	56.213	EPSD	TCGA;COSMIC	72.838	Loss
CMGC_GSK_GSK3A_ST	Q13563	PKD2	P49840	GSK3A	S808	R803Q	803	Missense	distal	-5	no	78.504	80.854	EPSD	TCGA;COSMIC	72.838	Up-regulation
CMGC_GSK_GSK3A_ST	Q13563	PKD2	P49840	GSK3A	S820	G821R	821	Missense	proximal	1	no	72.355	74.178	EPSD	TCGA	72.838	Gain
CMGC_GSK_GSK3A_ST	Q13563	PKD2	P49840	GSK3A	S947	R940L	940	Missense	distal	-7	no	77.296	76.527	EPSD	TCGA;COSMIC	72.838	Down-regulation
CMGC_GSK_GSK3A_ST	Q13563	PKD2	P49840	GSK3A	S947	G954S	954	Missense	distal	7	no	77.296	77.211	EPSD	TCGA	72.838	Down-regulation
CMGC_GSK_GSK3A_ST	Q13563	PKD2	P49840	GSK3A	S947	S949F	949	Missense	proximal	2	no	77.296	73.703	EPSD	TCGA;COSMIC	72.838	Down-regulation
CMGC_GSK_GSK3A_ST	Q13563	PKD2	P49840	GSK3A	S947	R940H	940	Missense	distal	-7	no	77.296	79.364	EPSD	TCGA;COSMIC	72.838	Up-regulation
CMGC_GSK_GSK3A_ST	Q13563	PKD2	P49840	GSK3A	S948	G954S	954	Missense	distal	6	no	76.002	76.955	EPSD	TCGA	72.838	Up-regulation
CMGC_GSK_GSK3A_ST	Q13563	PKD2	P49840	GSK3A	S948	S949F	949	Missense	proximal	1	no	76.002	75.957	EPSD	TCGA;COSMIC	72.838	Down-regulation
CMGC_GSK_GSK3A_ST	Q13563	PKD2	P49840	GSK3A	S949	G954S	954	Missense	distal	5	no	77.361	77.394	EPSD	TCGA	72.838	Up-regulation
CMGC_GSK_GSK3A_ST	Q13563	PKD2	P49840	GSK3A	S949	S949F	949	Missense	central	0	yes	77.361	0.000	EPSD	TCGA;COSMIC	72.838	Loss
CMGC_GSK_GSK3A_ST	Q07817	BCL2L1	P49840	GSK3A	S62	A64V	64	Missense	proximal	2	no	89.682	88.865	PhosphoSitePlus	TCGA	72.838	Down-regulation
CMGC_GSK_GSK3A_ST	O15084	ANKRD28	P49840	GSK3A	T528	E527K	527	Missense	proximal	-1	no	78.477	76.472	EPSD	TCGA;ICGC;COSMIC	72.838	Down-regulation
CMGC_GSK_GSK3A_ST	O15084	ANKRD28	P49840	GSK3A	T528	E527G	527	Missense	proximal	-1	no	78.477	77.406	EPSD	TCGA;ICGC;COSMIC	72.838	Down-regulation
CMGC_GSK_GSK3A_ST	O15084	ANKRD28	P49840	GSK3A	T528	E535V	535	Missense	distal	7	no	78.477	76.891	EPSD	TCGA;ICGC;COSMIC	72.838	Down-regulation
CMGC_GSK_GSK3A_ST	O15084	ANKRD28	P49840	GSK3A	S537	E535V	535	Missense	proximal	-2	no	74.958	74.391	EPSD	TCGA;ICGC;COSMIC	72.838	Down-regulation
CMGC_GSK_GSK3A_ST	O15084	ANKRD28	P49840	GSK3A	S537	S537A	537	Missense	central	0	yes	74.958	0.000	EPSD	TCGA;ICGC;COSMIC	72.838	Loss
CMGC_GSK_GSK3A_ST	O15084	ANKRD28	P49840	GSK3A	S988	P991R	991	Missense	distal	3	no	75.816	74.769	EPSD	TCGA;COSMIC	72.838	Down-regulation
CMGC_GSK_GSK3A_ST	O15084	ANKRD28	P49840	GSK3A	S990	F997S	997	Missense	distal	7	no	79.689	82.108	EPSD	TCGA	72.838	Up-regulation
CMGC_GSK_GSK3A_ST	O15084	ANKRD28	P49840	GSK3A	S990	P991R	991	Missense	proximal	1	no	79.689	71.036	EPSD	TCGA;COSMIC	72.838	Loss
CMGC_GSK_GSK3A_ST	O15084	ANKRD28	P49840	GSK3A	S1007	E1013K	1013	Missense	distal	6	no	83.117	83.663	PhosphoSitePlus	TCGA;ICGC;COSMIC	72.838	Up-regulation
CMGC_GSK_GSK3A_ST	O15084	ANKRD28	P49840	GSK3A	S1007	A1014V	1014	Missense	distal	7	no	83.117	81.810	PhosphoSitePlus	TCGA;ICGC;COSMIC	72.838	Down-regulation
CMGC_GSK_GSK3A_ST	P13051	UNG	P49840	GSK3A	T60	G59R	59	Missense	proximal	-1	no	98.672	98.398	EPSD;PhosphoSitePlus	TCGA;COSMIC	72.838	Down-regulation
CMGC_GSK_GSK3A_ST	P13051	UNG	P49840	GSK3A	S63	G59R	59	Missense	distal	-4	no	82.301	83.770	EPSD	TCGA;COSMIC	72.838	Up-regulation
CMGC_GSK_GSK3A_ST	P13051	UNG	P49840	GSK3A	S64	G59R	59	Missense	distal	-5	no	94.217	92.728	PhosphoSitePlus;EPSD	TCGA;COSMIC	72.838	Down-regulation
CMGC_GSK_GSK3A_ST	P13051	UNG	P49840	GSK3A	S279	P278S	278	Missense	proximal	-1	no	86.903	86.006	EPSD	TCGA;COSMIC	72.838	Down-regulation
CMGC_GSK_GSK3A_ST	P13051	UNG	P49840	GSK3A	S279	G286R	286	Missense	distal	7	no	86.903	86.282	EPSD	TCGA	72.838	Down-regulation
CMGC_GSK_GSK3A_ST	Q9Y4H4	GPSM3	P49840	GSK3A	S35	R34Q	34	Missense	proximal	-1	no	83.101	84.274	PhosphoSitePlus	TCGA;ICGC;COSMIC	72.838	Up-regulation
CMGC_GSK_GSK3A_ST	Q9Y4H4	GPSM3	P49840	GSK3A	S39	R34Q	34	Missense	distal	-5	no	86.623	88.972	EPSD	TCGA;ICGC;COSMIC	72.838	Up-regulation
CMGC_GSK_GSK3A_ST	Q9Y4H4	GPSM3	P49840	GSK3A	S39	R46C	46	Missense	distal	7	no	86.623	86.346	EPSD	TCGA;ICGC;COSMIC	72.838	Down-regulation
CMGC_GSK_GSK3A_ST	Q9Y4H4	GPSM3	P49840	GSK3A	T45	P52S	52	Missense	distal	7	no	79.014	78.672	EPSD	TCGA;ICGC;COSMIC	72.838	Down-regulation
CMGC_GSK_GSK3A_ST	Q9Y4H4	GPSM3	P49840	GSK3A	T45	R46C	46	Missense	proximal	1	no	79.014	60.625	EPSD	TCGA;ICGC;COSMIC	72.838	Loss
CMGC_GSK_GSK3A_ST	Q9Y4H4	GPSM3	P49840	GSK3A	S74	V69E	69	Missense	distal	-5	no	75.614	75.604	EPSD	TCGA;ICGC;COSMIC	72.838	Down-regulation
CMGC_GSK_GSK3A_ST	Q9Y4H4	GPSM3	P49840	GSK3A	S74	R81S	81	Missense	distal	7	no	75.614	76.150	EPSD	TCGA;ICGC;COSMIC	72.838	Up-regulation
CMGC_GSK_GSK3A_ST	Q9Y4H4	GPSM3	P49840	GSK3A	T86	A82V	82	Missense	distal	-4	no	73.753	72.922	EPSD	TCGA;ICGC;COSMIC	72.838	Down-regulation
CMGC_GSK_GSK3A_ST	Q9Y4H4	GPSM3	P49840	GSK3A	T86	R81S	81	Missense	distal	-5	no	73.753	75.427	EPSD	TCGA;ICGC;COSMIC	72.838	Up-regulation
CMGC_GSK_GSK3A_ST	Q9NZ72	STMN3	P49840	GSK3A	S60	F54L	54	Missense	distal	-6	no	87.763	86.313	PhosphoSitePlus	TCGA;COSMIC	72.838	Down-regulation
CMGC_GSK_GSK3A_ST	Q9NZ72	STMN3	P49840	GSK3A	S60	S65F	65	Missense	distal	5	no	87.763	90.273	PhosphoSitePlus	TCGA	72.838	Up-regulation
CMGC_GSK_GSK3A_ST	Q9NZ72	STMN3	P49840	GSK3A	S65	S65F	65	Missense	central	0	yes	73.156	0.000	EPSD	TCGA	72.838	Loss
CMGC_GSK_GSK3A_ST	Q9NZ72	STMN3	P49840	GSK3A	S68	P74S	74	Missense	distal	6	no	77.617	77.067	EPSD	TCGA;COSMIC	72.838	Down-regulation
CMGC_GSK_GSK3A_ST	Q9NZ72	STMN3	P49840	GSK3A	S68	S65F	65	Missense	distal	-3	no	77.617	76.388	EPSD	TCGA	72.838	Down-regulation
CMGC_GSK_GSK3A_ST	Q9NZ72	STMN3	P49840	GSK3A	S73	P74S	74	Missense	proximal	1	no	86.291	70.599	EPSD	TCGA;COSMIC	72.838	Loss
CMGC_GSK_GSK3A_ST	Q16555	DPYSL2	P49840	GSK3A	T74	R75C	75	Missense	proximal	1	no	73.917	55.528	EPSD	TCGA;COSMIC	72.838	Loss
CMGC_GSK_GSK3A_ST	Q16555	DPYSL2	P49840	GSK3A	T74	P79S	79	Missense	distal	5	no	73.917	68.360	EPSD	TCGA	72.838	Loss
CMGC_GSK_GSK3A_ST	Q16555	DPYSL2	P49840	GSK3A	T74	P67S	67	Missense	distal	-7	no	73.917	73.762	EPSD	TCGA;COSMIC	72.838	Down-regulation
CMGC_GSK_GSK3A_ST	Q16555	DPYSL2	P49840	GSK3A	T74	R75H	75	Missense	proximal	1	no	73.917	56.156	EPSD	TCGA;COSMIC	72.838	Loss
CMGC_GSK_GSK3A_ST	Q16555	DPYSL2	P49840	GSK3A	S304	F301V	301	Missense	distal	-3	no	92.097	93.457	EPSD	TCGA;COSMIC	72.838	Up-regulation
CMGC_GSK_GSK3A_ST	Q16555	DPYSL2	P49840	GSK3A	S308	F301V	301	Missense	distal	-7	no	79.042	82.205	EPSD	TCGA;COSMIC	72.838	Up-regulation
CMGC_GSK_GSK3A_ST	Q16555	DPYSL2	P49840	GSK3A	S465	R467C	467	Missense	proximal	2	no	80.668	77.718	EPSD	TCGA;COSMIC	72.838	Down-regulation
CMGC_GSK_GSK3A_ST	Q16555	DPYSL2	P49840	GSK3A	T509	V513I	513	Missense	distal	4	no	92.986	94.492	EPSD	TCGA;COSMIC	72.838	Up-regulation
CMGC_GSK_GSK3A_ST	Q16555	DPYSL2	P49840	GSK3A	T509	T509M	509	Missense	central	0	yes	92.986	0.000	EPSD	TCGA;COSMIC	72.838	Loss
CMGC_GSK_GSK3A_ST	Q16555	DPYSL2	P49840	GSK3A	T509	P515S	515	Missense	distal	6	no	92.986	92.437	EPSD	TCGA;COSMIC	72.838	Down-regulation
CMGC_GSK_GSK3A_ST	Q16555	DPYSL2	P49840	GSK3A	T514	V513I	513	Missense	proximal	-1	no	86.186	84.738	EPSD	TCGA;COSMIC	72.838	Down-regulation
CMGC_GSK_GSK3A_ST	Q16555	DPYSL2	P49840	GSK3A	T514	T509M	509	Missense	distal	-5	no	86.186	84.217	EPSD	TCGA;COSMIC	72.838	Down-regulation
CMGC_GSK_GSK3A_ST	Q16555	DPYSL2	P49840	GSK3A	T514	P515S	515	Missense	proximal	1	no	86.186	70.494	EPSD	TCGA;COSMIC	72.838	Loss
CMGC_GSK_GSK3A_ST	Q16555	DPYSL2	P49840	GSK3A	T514	T521M	521	Missense	distal	7	no	86.186	84.731	EPSD	TCGA;COSMIC	72.838	Down-regulation
CMGC_GSK_GSK3A_ST	Q16555	DPYSL2	P49840	GSK3A	S517	V513I	513	Missense	distal	-4	no	75.267	75.260	EPSD	TCGA;COSMIC	72.838	Down-regulation
CMGC_GSK_GSK3A_ST	Q16555	DPYSL2	P49840	GSK3A	S517	P515S	515	Missense	proximal	-2	no	75.267	75.115	EPSD	TCGA;COSMIC	72.838	Down-regulation
CMGC_GSK_GSK3A_ST	Q16555	DPYSL2	P49840	GSK3A	S517	T521M	521	Missense	distal	4	no	75.267	72.610	EPSD	TCGA;COSMIC	72.838	Loss
CMGC_GSK_GSK3A_ST	Q16555	DPYSL2	P49840	GSK3A	S518	V513I	513	Missense	distal	-5	no	88.263	87.126	PhosphoSitePlus	TCGA;COSMIC	72.838	Down-regulation
CMGC_GSK_GSK3A_ST	Q16555	DPYSL2	P49840	GSK3A	S518	P515S	515	Missense	distal	-3	no	88.263	87.624	PhosphoSitePlus	TCGA;COSMIC	72.838	Down-regulation
CMGC_GSK_GSK3A_ST	Q16555	DPYSL2	P49840	GSK3A	S518	T521M	521	Missense	distal	3	no	88.263	84.935	PhosphoSitePlus	TCGA;COSMIC	72.838	Down-regulation
CMGC_GSK_GSK3A_ST	Q16555	DPYSL2	P49840	GSK3A	T521	P515S	515	Missense	distal	-6	no	74.940	74.886	EPSD	TCGA;COSMIC	72.838	Down-regulation
CMGC_GSK_GSK3A_ST	Q16555	DPYSL2	P49840	GSK3A	T521	T521M	521	Missense	central	0	yes	74.940	0.000	EPSD	TCGA;COSMIC	72.838	Loss
CMGC_GSK_GSK3A_ST	Q16555	DPYSL2	P49840	GSK3A	S537	S537P	537	Missense	central	0	yes	81.239	0.000	EPSD	TCGA;COSMIC	72.838	Loss
CMGC_GSK_GSK3A_ST	Q16555	DPYSL2	P49840	GSK3A	S542	S537P	537	Missense	distal	-5	no	80.714	80.627	EPSD	TCGA;COSMIC	72.838	Down-regulation
CMGC_GSK_GSK3A_ST	Q16555	DPYSL2	P49840	GSK3A	S542	Q545H	545	Missense	distal	3	no	80.714	86.559	EPSD	TCGA	72.838	Up-regulation
Atypical_PDHK_PDHK_PDK2_ST	P08559	PDHA1	Q15119	PDK2	S232	A236D	236	Missense	distal	4	no	4.198	4.173	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	1.129	Down-regulation
Atypical_PDHK_PDHK_PDK2_ST	P08559	PDHA1	Q15119	PDK2	T240	A236D	236	Missense	distal	-4	no	1.294	1.342	EPSD	TCGA;ICGC;COSMIC	1.129	Up-regulation
Atypical_PDHK_PDHK_PDK2_ST	P29803	PDHA2	Q15119	PDK2	S128	Y123C	123	Missense	distal	-5	no	1.535	1.534	EPSD	TCGA;ICGC;COSMIC	1.129	Down-regulation
Atypical_PDHK_PDHK_PDK2_ST	P29803	PDHA2	Q15119	PDK2	S128	E135Q	135	Missense	distal	7	no	1.535	1.533	EPSD	TCGA;ICGC;COSMIC	1.129	Down-regulation
Atypical_PDHK_PDHK_PDK2_ST	P29803	PDHA2	Q15119	PDK2	S150	K156N	156	Missense	distal	6	no	2.111	2.214	EPSD	TCGA;ICGC;COSMIC	1.129	Up-regulation
Atypical_PDHK_PDHK_PDK2_ST	P29803	PDHA2	Q15119	PDK2	S150	G146E	146	Missense	distal	-4	no	2.111	1.980	EPSD	TCGA;ICGC;COSMIC;GDSC;CCLE	1.129	Down-regulation
Atypical_PDHK_PDHK_PDK2_ST	P29803	PDHA2	Q15119	PDK2	S150	G149E	149	Missense	proximal	-1	no	2.111	2.110	EPSD	TCGA;ICGC;COSMIC	1.129	Down-regulation
Atypical_PDHK_PDHK_PDK2_ST	P29803	PDHA2	Q15119	PDK2	S150	K156T	156	Missense	distal	6	no	2.111	2.098	EPSD	TCGA;ICGC;COSMIC	1.129	Down-regulation
Atypical_PDHK_PDHK_PDK2_ST	P29803	PDHA2	Q15119	PDK2	S230	G228V	228	Missense	proximal	-2	no	2.450	1.314	EPSD	TCGA;ICGC;COSMIC	1.129	Down-regulation
Atypical_PDHK_PDHK_PDK2_ST	P29803	PDHA2	Q15119	PDK2	S230	Y225F	225	Missense	distal	-5	no	2.450	2.453	EPSD	TCGA;ICGC;COSMIC	1.129	Up-regulation
Atypical_PDHK_PDHK_PDK2_ST	P29803	PDHA2	Q15119	PDK2	S230	Y225C	225	Missense	distal	-5	no	2.450	2.449	EPSD	TCGA;ICGC;COSMIC	1.129	Down-regulation
Atypical_PDHK_PDHK_PDK2_ST	P29803	PDHA2	Q15119	PDK2	S230	E232V	232	Missense	proximal	2	no	2.450	2.393	EPSD	TCGA;ICGC;COSMIC	1.129	Down-regulation
Atypical_PDHK_PDHK_PDK2_ST	P29803	PDHA2	Q15119	PDK2	S230	G226R	226	Missense	distal	-4	no	2.450	2.394	EPSD	TCGA;ICGC;COSMIC	1.129	Down-regulation
Atypical_PDHK_PDHK_PDK2_ST	P29803	PDHA2	Q15119	PDK2	S230	R233K	233	Missense	distal	3	no	2.450	2.457	EPSD	TCGA;ICGC;COSMIC	1.129	Up-regulation
Atypical_PDHK_PDHK_PDK2_ST	P29803	PDHA2	Q15119	PDK2	T231	E232V	232	Missense	proximal	1	no	0.731	1.366	EPSD	TCGA;ICGC;COSMIC	1.129	Gain
Atypical_PDHK_PDHK_PDK2_ST	P29803	PDHA2	Q15119	PDK2	T284	Y285H	285	Missense	proximal	1	no	1.160	-0.162	EPSD	TCGA;ICGC;COSMIC	1.129	Loss
Atypical_PDHK_PDHK_PDK2_ST	P29803	PDHA2	Q15119	PDK2	T284	M280I	280	Missense	distal	-4	no	1.160	1.266	EPSD	TCGA;ICGC;COSMIC	1.129	Up-regulation
Atypical_PDHK_PDHK_PDK2_ST	P29803	PDHA2	Q15119	PDK2	S291	Y285H	285	Missense	distal	-6	no	4.883	4.660	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	1.129	Down-regulation
Atypical_PDHK_PDHK_PDK2_ST	P29803	PDHA2	Q15119	PDK2	S291	M292I	292	Missense	proximal	1	no	4.883	4.092	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	1.129	Down-regulation
Atypical_PDHK_PDHK_PDK2_ST	P29803	PDHA2	Q15119	PDK2	S291	S298C	298	Missense	distal	7	no	4.883	4.881	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	1.129	Down-regulation
Atypical_PDHK_PDHK_PDK2_ST	P29803	PDHA2	Q15119	PDK2	S291	S293T	293	Missense	proximal	2	no	4.883	4.870	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	1.129	Down-regulation
Atypical_PDHK_PDHK_PDK2_ST	P29803	PDHA2	Q15119	PDK2	S298	R300C	300	Missense	proximal	2	no	5.732	5.735	PhosphoSitePlus;EPSD	TCGA;ICGC;COSMIC	1.129	Up-regulation
Atypical_PDHK_PDHK_PDK2_ST	P29803	PDHA2	Q15119	PDK2	S298	R302Q	302	Missense	distal	4	no	5.732	5.708	PhosphoSitePlus;EPSD	TCGA;ICGC;COSMIC	1.129	Down-regulation
Atypical_PDHK_PDHK_PDK2_ST	P29803	PDHA2	Q15119	PDK2	S298	R300H	300	Missense	proximal	2	no	5.732	5.710	PhosphoSitePlus;EPSD	TCGA;ICGC;COSMIC;CCLE	1.129	Down-regulation
Atypical_PDHK_PDHK_PDK2_ST	P29803	PDHA2	Q15119	PDK2	S298	M292I	292	Missense	distal	-6	no	5.732	5.519	PhosphoSitePlus;EPSD	TCGA;ICGC;COSMIC	1.129	Down-regulation
Atypical_PDHK_PDHK_PDK2_ST	P29803	PDHA2	Q15119	PDK2	S298	R300S	300	Missense	proximal	2	no	5.732	5.751	PhosphoSitePlus;EPSD	TCGA;ICGC;COSMIC	1.129	Up-regulation
Atypical_PDHK_PDHK_PDK2_ST	P29803	PDHA2	Q15119	PDK2	S298	R300L	300	Missense	proximal	2	no	5.732	5.746	PhosphoSitePlus;EPSD	TCGA;ICGC;COSMIC	1.129	Up-regulation
Atypical_PDHK_PDHK_PDK2_ST	P29803	PDHA2	Q15119	PDK2	S298	S298C	298	Missense	central	0	yes	5.732	0.000	PhosphoSitePlus;EPSD	TCGA;ICGC;COSMIC	1.129	Loss
Atypical_PDHK_PDHK_PDK2_ST	P29803	PDHA2	Q15119	PDK2	S298	S293T	293	Missense	distal	-5	no	5.732	5.734	PhosphoSitePlus;EPSD	TCGA;ICGC;COSMIC	1.129	Up-regulation
CAMK_TSSK_TSSK4_ST	P16220	CREB1	Q6SA08	TSSK4	S98	S103A	103	Missense	distal	5	no	1.808	2.115	EPSD	TCGA;COSMIC	1.711	Up-regulation
CAMK_TSSK_TSSK4_ST	P16220	CREB1	Q6SA08	TSSK4	S111	D116G	116	Missense	distal	5	no	1.918	1.970	EPSD	TCGA;COSMIC	1.711	Up-regulation
CAMK_TSSK_TSSK4_ST	P16220	CREB1	Q6SA08	TSSK4	S111	Q112H	112	Missense	proximal	1	no	1.918	1.855	EPSD	TCGA;COSMIC	1.711	Down-regulation
CAMK_TSSK_TSSK4_ST	P16220	CREB1	Q6SA08	TSSK4	S133	L128I	128	Missense	distal	-5	no	8.812	8.302	PhosphoSitePlus	TCGA;COSMIC	1.711	Down-regulation
TK_Met_MET_Y	P09874	PARP1	P08581	MET	Y176	P174T	174	Missense	proximal	-2	no	30.180	27.119	EPSD	TCGA;ICGC;COSMIC	27.257	Loss
TK_Met_MET_Y	P09874	PARP1	P08581	MET	Y176	A178V	178	Missense	proximal	2	no	30.180	29.724	EPSD	TCGA;ICGC;COSMIC;GDSC;CCLE	27.257	Down-regulation
TK_Met_MET_Y	P09874	PARP1	P08581	MET	Y309	D307N	307	Missense	proximal	-2	no	30.165	24.142	EPSD	TCGA;ICGC;COSMIC	27.257	Loss
TK_Met_MET_Y	P09874	PARP1	P08581	MET	Y737	R735C	735	Missense	proximal	-2	no	27.512	25.887	EPSD	TCGA;ICGC;COSMIC	27.257	Loss
TK_Met_MET_Y	P09874	PARP1	P08581	MET	Y737	R735H	735	Missense	proximal	-2	no	27.512	29.112	EPSD	TCGA;ICGC	27.257	Up-regulation
TK_Met_MET_Y	P09874	PARP1	P08581	MET	Y907	S904T	904	Missense	distal	-3	no	35.103	28.821	PhosphoSitePlus	TCGA;ICGC;COSMIC	27.257	Down-regulation
TK_Met_MET_Y	Q04912	MST1R	P08581	MET	Y1238	R1231C	1231	Missense	distal	-7	no	39.124	38.517	EPSD;PhosphoSitePlus	TCGA;COSMIC	27.257	Down-regulation
TK_Met_MET_Y	Q04912	MST1R	P08581	MET	Y1238	D1235E	1235	Missense	distal	-3	no	39.124	37.455	EPSD;PhosphoSitePlus	TCGA;COSMIC	27.257	Down-regulation
TK_Met_MET_Y	Q04912	MST1R	P08581	MET	Y1238	R1231H	1231	Missense	distal	-7	no	39.124	39.161	EPSD;PhosphoSitePlus	TCGA;COSMIC	27.257	Up-regulation
TK_Met_MET_Y	Q04912	MST1R	P08581	MET	Y1238	R1245C	1245	Missense	distal	7	no	39.124	38.970	EPSD;PhosphoSitePlus	TCGA;COSMIC	27.257	Down-regulation
TK_Met_MET_Y	Q04912	MST1R	P08581	MET	Y1238	R1245H	1245	Missense	distal	7	no	39.124	39.112	EPSD;PhosphoSitePlus	TCGA;COSMIC	27.257	Down-regulation
TK_Met_MET_Y	Q04912	MST1R	P08581	MET	Y1239	D1235E	1235	Missense	distal	-4	no	39.326	38.617	EPSD;PhosphoSitePlus	TCGA;COSMIC	27.257	Down-regulation
TK_Met_MET_Y	Q04912	MST1R	P08581	MET	Y1239	R1245C	1245	Missense	distal	6	no	39.326	38.182	EPSD;PhosphoSitePlus	TCGA;COSMIC	27.257	Down-regulation
TK_Met_MET_Y	Q04912	MST1R	P08581	MET	Y1239	R1245H	1245	Missense	distal	6	no	39.326	39.385	EPSD;PhosphoSitePlus	TCGA;COSMIC	27.257	Up-regulation
TK_Met_MET_Y	Q04912	MST1R	P08581	MET	Y1360	M1361I	1361	Missense	proximal	1	no	30.446	27.272	EPSD;PhosphoSitePlus	TCGA;COSMIC	27.257	Down-regulation
TK_Met_MET_Y	P35568	IRS1	P08581	MET	Y431	S428L	428	Missense	distal	-3	no	45.192	26.353	EPSD	TCGA;ICGC;COSMIC	27.257	Loss
TK_Met_MET_Y	P35568	IRS1	P08581	MET	Y431	G424S	424	Missense	distal	-7	no	45.192	46.914	EPSD	TCGA;ICGC;COSMIC	27.257	Up-regulation
TK_Met_MET_Y	P35568	IRS1	P08581	MET	Y431	F438V	438	Missense	distal	7	no	45.192	45.340	EPSD	TCGA;ICGC;COSMIC	27.257	Up-regulation
TK_Met_MET_Y	P35568	IRS1	P08581	MET	Y551	P556S	556	Missense	distal	5	no	40.727	40.940	EPSD	TCGA;ICGC;COSMIC	27.257	Up-regulation
TK_Met_MET_Y	P35568	IRS1	P08581	MET	Y551	S544L	544	Missense	distal	-7	no	40.727	38.007	EPSD	TCGA;ICGC;COSMIC	27.257	Down-regulation
TK_Met_MET_Y	P35568	IRS1	P08581	MET	Y551	E553D	553	Missense	proximal	2	no	40.727	40.323	EPSD	TCGA;ICGC;COSMIC	27.257	Down-regulation
TK_Met_MET_Y	P35568	IRS1	P08581	MET	Y582	E588D	588	Missense	distal	6	no	26.809	27.363	EPSD	TCGA;ICGC;COSMIC	27.257	Gain
TK_Met_MET_Y	P35568	IRS1	P08581	MET	Y612	H607R	607	Missense	distal	-5	no	72.978	72.813	PhosphoSitePlus;EPSD	TCGA;ICGC	27.257	Down-regulation
TK_Met_MET_Y	P35568	IRS1	P08581	MET	Y612	G611C	611	Missense	proximal	-1	no	72.978	72.918	PhosphoSitePlus;EPSD	TCGA;ICGC;COSMIC	27.257	Down-regulation
TK_Met_MET_Y	P35568	IRS1	P08581	MET	Y695	V689F	689	Missense	distal	-6	no	33.992	34.271	EPSD	TCGA;ICGC;COSMIC	27.257	Up-regulation
TK_Met_MET_Y	P35568	IRS1	P08581	MET	Y695	P690H	690	Missense	distal	-5	no	33.992	33.594	EPSD	TCGA	27.257	Down-regulation
TK_Met_MET_Y	P35568	IRS1	P08581	MET	Y732	M733I	733	Missense	proximal	1	no	36.487	33.314	EPSD	TCGA;ICGC;COSMIC	27.257	Down-regulation
TK_Met_MET_Y	P35568	IRS1	P08581	MET	Y732	C728Y	728	Missense	distal	-4	no	36.487	37.102	EPSD	TCGA;COSMIC	27.257	Up-regulation
TK_Met_MET_Y	P35568	IRS1	P08581	MET	Y732	D731E	731	Missense	proximal	-1	no	36.487	35.948	EPSD	TCGA;ICGC;COSMIC	27.257	Down-regulation
TK_Met_MET_Y	P35568	IRS1	P08581	MET	Y764	S770Y	770	Missense	distal	6	no	31.418	28.495	EPSD	TCGA;ICGC;COSMIC	27.257	Down-regulation
TK_Met_MET_Y	P35568	IRS1	P08581	MET	Y764	R769K	769	Missense	distal	5	no	31.418	32.673	EPSD	TCGA;ICGC;COSMIC	27.257	Up-regulation
TK_Met_MET_Y	P35568	IRS1	P08581	MET	Y765	S770Y	770	Missense	distal	5	no	29.558	25.692	EPSD	TCGA;ICGC;COSMIC	27.257	Loss
TK_Met_MET_Y	P35568	IRS1	P08581	MET	Y765	R769K	769	Missense	distal	4	no	29.558	32.290	EPSD	TCGA;ICGC;COSMIC	27.257	Up-regulation
TK_Met_MET_Y	P35568	IRS1	P08581	MET	Y941	E939Q	939	Missense	proximal	-2	no	35.701	28.904	EPSD	TCGA;ICGC;COSMIC	27.257	Down-regulation
TK_Met_MET_Y	P35568	IRS1	P08581	MET	Y941	E939K	939	Missense	proximal	-2	no	35.701	30.228	EPSD	TCGA;ICGC;COSMIC	27.257	Down-regulation
TK_Met_MET_Y	P35568	IRS1	P08581	MET	Y989	R986W	986	Missense	distal	-3	no	48.647	45.300	EPSD	TCGA;ICGC;COSMIC;GDSC;CCLE	27.257	Down-regulation
TK_Met_MET_Y	P35568	IRS1	P08581	MET	Y1001	S1005L	1005	Missense	distal	4	no	48.998	38.991	EPSD	TCGA;ICGC	27.257	Down-regulation
TK_Met_MET_Y	P35568	IRS1	P08581	MET	Y1012	S1005L	1005	Missense	distal	-7	no	54.832	52.112	EPSD	TCGA;ICGC	27.257	Down-regulation
TK_Met_MET_Y	P35568	IRS1	P08581	MET	Y1012	R1016Q	1016	Missense	distal	4	no	54.832	56.010	EPSD	TCGA;ICGC;COSMIC	27.257	Up-regulation
TK_Met_MET_Y	Q05397	PTK2	P08581	MET	Y5	H12Y	12	Missense	distal	7	no	33.030	32.950	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	27.257	Down-regulation
TK_Met_MET_Y	Q05397	PTK2	P08581	MET	Y5	A2T	2	Missense	distal	-3	no	33.030	31.505	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	27.257	Down-regulation
TK_Met_MET_Y	Q05397	PTK2	P08581	MET	Y194	V201I	201	Missense	distal	7	no	37.254	37.123	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	27.257	Down-regulation
TK_Met_MET_Y	Q05397	PTK2	P08581	MET	Y397	E403K	403	Missense	distal	6	no	43.868	43.499	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	27.257	Down-regulation
TK_Met_MET_Y	Q05397	PTK2	P08581	MET	Y397	D395Y	395	Missense	proximal	-2	no	43.868	35.488	EPSD;PhosphoSitePlus	TCGA;ICGC	27.257	Down-regulation
TK_Met_MET_Y	Q05397	PTK2	P08581	MET	Y397	E404G	404	Missense	distal	7	no	43.868	43.562	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	27.257	Down-regulation
TK_Met_MET_Y	Q05397	PTK2	P08581	MET	Y407	E403K	403	Missense	distal	-4	no	72.144	70.331	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	27.257	Down-regulation
TK_Met_MET_Y	Q05397	PTK2	P08581	MET	Y407	E404G	404	Missense	distal	-3	no	72.144	64.826	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	27.257	Down-regulation
TK_Met_MET_Y	Q05397	PTK2	P08581	MET	Y720	S725F	725	Missense	distal	5	no	38.240	33.091	EPSD	TCGA;ICGC	27.257	Down-regulation
TK_Met_MET_Y	Q05397	PTK2	P08581	MET	Y720	P718L	718	Missense	proximal	-2	no	38.240	29.220	EPSD	TCGA;ICGC;COSMIC	27.257	Down-regulation
TK_Met_MET_Y	Q05397	PTK2	P08581	MET	Y720	P723L	723	Missense	distal	3	no	38.240	28.907	EPSD	TCGA;ICGC;COSMIC	27.257	Down-regulation
TK_Met_MET_Y	Q05397	PTK2	P08581	MET	Y720	K714N	714	Missense	distal	-6	no	38.240	38.330	EPSD	TCGA;ICGC;COSMIC	27.257	Up-regulation
TK_Met_MET_Y	Q05397	PTK2	P08581	MET	Y742	N740D	740	Missense	proximal	-2	no	25.972	31.996	EPSD	TCGA;ICGC;COSMIC	27.257	Gain
TK_Met_MET_Y	Q05397	PTK2	P08581	MET	Y742	N740S	740	Missense	proximal	-2	no	25.972	32.469	EPSD	TCGA;ICGC;COSMIC	27.257	Gain
TK_Met_MET_Y	Q05397	PTK2	P08581	MET	Y761	L767F	767	Missense	distal	6	no	32.646	32.933	EPSD	TCGA;ICGC;COSMIC	27.257	Up-regulation
TK_Met_MET_Y	Q05397	PTK2	P08581	MET	Y761	A755V	755	Missense	distal	-6	no	32.646	32.966	EPSD	TCGA;ICGC;COSMIC	27.257	Up-regulation
TK_Met_MET_Y	P06213	INSR	P08581	MET	Y1189	T1187M	1187	Missense	proximal	-2	no	27.191	29.006	EPSD	TCGA;COSMIC	27.257	Gain
TK_Met_MET_Y	P06213	INSR	P08581	MET	Y1189	R1191Q	1191	Missense	proximal	2	no	27.191	27.474	EPSD	TCGA;COSMIC	27.257	Gain
TK_Met_MET_Y	P06213	INSR	P08581	MET	Y1190	E1186Q	1186	Missense	distal	-4	no	31.563	29.009	EPSD	TCGA;COSMIC	27.257	Down-regulation
TK_Met_MET_Y	P06213	INSR	P08581	MET	Y1190	T1187M	1187	Missense	distal	-3	no	31.563	29.709	EPSD	TCGA;COSMIC	27.257	Down-regulation
TK_Met_MET_Y	P06213	INSR	P08581	MET	Y1190	R1191Q	1191	Missense	proximal	1	no	31.563	32.285	EPSD	TCGA;COSMIC	27.257	Up-regulation
TK_Met_MET_Y	P06213	INSR	P08581	MET	Y1190	G1193W	1193	Missense	distal	3	no	31.563	37.433	EPSD	TCGA	27.257	Up-regulation
TK_Met_MET_Y	P06213	INSR	P08581	MET	Y1361	G1367D	1367	Missense	distal	6	no	27.046	29.241	EPSD	TCGA;COSMIC	27.257	Gain
CMGC_DYRK_DYRK1_DYRK1A_ST	P10636	MAPT	Q13627	DYRK1A	T50	D54E	54	Missense	distal	4	no	39.232	38.974	EPSD	TCGA;ICGC;COSMIC	34.163	Down-regulation
CMGC_DYRK_DYRK1_DYRK1A_ST	P10636	MAPT	Q13627	DYRK1A	T50	T52I	52	Missense	proximal	2	no	39.232	38.352	EPSD	TCGA;ICGC;COSMIC	34.163	Down-regulation
CMGC_DYRK_DYRK1_DYRK1A_ST	P10636	MAPT	Q13627	DYRK1A	T50	P47S	47	Missense	distal	-3	no	39.232	42.004	EPSD	TCGA;ICGC;COSMIC	34.163	Up-regulation
CMGC_DYRK_DYRK1_DYRK1A_ST	P10636	MAPT	Q13627	DYRK1A	T50	P47L	47	Missense	distal	-3	no	39.232	37.239	EPSD	TCGA;ICGC;COSMIC	34.163	Down-regulation
CMGC_DYRK_DYRK1_DYRK1A_ST	P10636	MAPT	Q13627	DYRK1A	T50	G55R	55	Missense	distal	5	no	39.232	39.579	EPSD	TCGA;ICGC;COSMIC	34.163	Up-regulation
CMGC_DYRK_DYRK1_DYRK1A_ST	P10636	MAPT	Q13627	DYRK1A	S64	A66S	66	Missense	proximal	2	no	41.642	41.341	EPSD	TCGA;ICGC;COSMIC	34.163	Down-regulation
CMGC_DYRK_DYRK1_DYRK1A_ST	P10636	MAPT	Q13627	DYRK1A	S64	P59L	59	Missense	distal	-5	no	41.642	40.206	EPSD	TCGA;ICGC;COSMIC	34.163	Down-regulation
CMGC_DYRK_DYRK1_DYRK1A_ST	P10636	MAPT	Q13627	DYRK1A	S64	P59T	59	Missense	distal	-5	no	41.642	40.550	EPSD	TCGA;ICGC;COSMIC	34.163	Down-regulation
CMGC_DYRK_DYRK1_DYRK1A_ST	P10636	MAPT	Q13627	DYRK1A	S64	G60S	60	Missense	distal	-4	no	41.642	41.664	EPSD	TCGA;ICGC;COSMIC	34.163	Up-regulation
CMGC_DYRK_DYRK1_DYRK1A_ST	P10636	MAPT	Q13627	DYRK1A	T69	A72V	72	Missense	distal	3	no	44.531	44.129	EPSD	TCGA;ICGC;COSMIC	34.163	Down-regulation
CMGC_DYRK_DYRK1_DYRK1A_ST	P10636	MAPT	Q13627	DYRK1A	T69	A66S	66	Missense	distal	-3	no	44.531	50.358	EPSD	TCGA;ICGC;COSMIC	34.163	Up-regulation
CMGC_DYRK_DYRK1_DYRK1A_ST	P10636	MAPT	Q13627	DYRK1A	T71	A72V	72	Missense	proximal	1	no	17.850	38.225	EPSD	TCGA;ICGC;COSMIC	34.163	Gain
CMGC_DYRK_DYRK1_DYRK1A_ST	P10636	MAPT	Q13627	DYRK1A	T111	E117K	117	Missense	distal	6	no	49.672	49.725	EPSD	TCGA;ICGC;COSMIC	34.163	Up-regulation
CMGC_DYRK_DYRK1_DYRK1A_ST	P10636	MAPT	Q13627	DYRK1A	T111	A118V	118	Missense	distal	7	no	49.672	49.852	EPSD	TCGA;ICGC;COSMIC	34.163	Up-regulation
CMGC_DYRK_DYRK1_DYRK1A_ST	P10636	MAPT	Q13627	DYRK1A	S171	R168H	168	Missense	distal	-3	no	40.913	25.581	EPSD	TCGA;ICGC;COSMIC	34.163	Loss
CMGC_DYRK_DYRK1_DYRK1A_ST	P10636	MAPT	Q13627	DYRK1A	S171	R168C	168	Missense	distal	-3	no	40.913	17.408	EPSD	TCGA;ICGC;COSMIC	34.163	Loss
CMGC_DYRK_DYRK1_DYRK1A_ST	P10636	MAPT	Q13627	DYRK1A	T173	R168H	168	Missense	distal	-5	no	40.645	39.295	EPSD	TCGA;ICGC;COSMIC	34.163	Down-regulation
CMGC_DYRK_DYRK1_DYRK1A_ST	P10636	MAPT	Q13627	DYRK1A	T173	R168C	168	Missense	distal	-5	no	40.645	38.644	EPSD	TCGA;ICGC;COSMIC	34.163	Down-regulation
CMGC_DYRK_DYRK1_DYRK1A_ST	P10636	MAPT	Q13627	DYRK1A	S214	P212L	212	Missense	proximal	-2	no	45.770	32.042	EPSD	TCGA;ICGC;COSMIC	34.163	Loss
CMGC_DYRK_DYRK1_DYRK1A_ST	P10636	MAPT	Q13627	DYRK1A	S214	E220K	220	Missense	distal	6	no	45.770	45.823	EPSD	TCGA;ICGC;COSMIC	34.163	Up-regulation
CMGC_DYRK_DYRK1_DYRK1A_ST	P10636	MAPT	Q13627	DYRK1A	S228	S232Y	232	Missense	distal	4	no	47.818	49.454	EPSD	TCGA;ICGC;COSMIC	34.163	Up-regulation
CMGC_DYRK_DYRK1_DYRK1A_ST	P10636	MAPT	Q13627	DYRK1A	S228	D223Y	223	Missense	distal	-5	no	47.818	47.957	EPSD	TCGA;ICGC;COSMIC	34.163	Up-regulation
CMGC_DYRK_DYRK1_DYRK1A_ST	P10636	MAPT	Q13627	DYRK1A	S228	S227F	227	Missense	proximal	-1	no	47.818	49.806	EPSD	TCGA;ICGC;COSMIC	34.163	Up-regulation
CMGC_DYRK_DYRK1_DYRK1A_ST	P10636	MAPT	Q13627	DYRK1A	S228	P234L	234	Missense	distal	6	no	47.818	47.890	EPSD	TCGA;ICGC;COSMIC	34.163	Up-regulation
CMGC_DYRK_DYRK1_DYRK1A_ST	P10636	MAPT	Q13627	DYRK1A	S235	S232Y	232	Missense	distal	-3	no	46.531	37.134	EPSD	TCGA;ICGC;COSMIC	34.163	Down-regulation
CMGC_DYRK_DYRK1_DYRK1A_ST	P10636	MAPT	Q13627	DYRK1A	S235	A240T	240	Missense	distal	5	no	46.531	48.394	EPSD	TCGA;ICGC;COSMIC	34.163	Up-regulation
CMGC_DYRK_DYRK1_DYRK1A_ST	P10636	MAPT	Q13627	DYRK1A	S235	P234L	234	Missense	proximal	-1	no	46.531	46.755	EPSD	TCGA;ICGC;COSMIC	34.163	Up-regulation
CMGC_DYRK_DYRK1_DYRK1A_ST	P10636	MAPT	Q13627	DYRK1A	S238	S232Y	232	Missense	distal	-6	no	39.382	38.476	EPSD	TCGA;ICGC;COSMIC	34.163	Down-regulation
CMGC_DYRK_DYRK1_DYRK1A_ST	P10636	MAPT	Q13627	DYRK1A	S238	A240T	240	Missense	proximal	2	no	39.382	38.822	EPSD	TCGA;ICGC;COSMIC	34.163	Down-regulation
CMGC_DYRK_DYRK1_DYRK1A_ST	P10636	MAPT	Q13627	DYRK1A	S238	P234L	234	Missense	distal	-4	no	39.382	39.380	EPSD	TCGA;ICGC;COSMIC	34.163	Down-regulation
CMGC_DYRK_DYRK1_DYRK1A_ST	P10636	MAPT	Q13627	DYRK1A	S238	R244Q	244	Missense	distal	6	no	39.382	39.390	EPSD	TCGA;ICGC;COSMIC	34.163	Up-regulation
CMGC_DYRK_DYRK1_DYRK1A_ST	P10636	MAPT	Q13627	DYRK1A	S411	P415L	415	Missense	distal	4	no	40.744	42.791	EPSD	TCGA;ICGC;COSMIC	34.163	Up-regulation
CMGC_DYRK_DYRK1_DYRK1A_ST	P10636	MAPT	Q13627	DYRK1A	T416	P415L	415	Missense	proximal	-1	no	53.618	53.841	EPSD	TCGA;ICGC;COSMIC	34.163	Up-regulation
CMGC_DYRK_DYRK1_DYRK1A_ST	P10636	MAPT	Q13627	DYRK1A	S428	A430S	430	Missense	proximal	2	no	43.557	43.255	EPSD	TCGA;ICGC;COSMIC	34.163	Down-regulation
CMGC_DYRK_DYRK1_DYRK1A_ST	P10636	MAPT	Q13627	DYRK1A	S428	V431L	431	Missense	distal	3	no	43.557	43.635	EPSD	TCGA;ICGC;COSMIC	34.163	Up-regulation
CMGC_DYRK_DYRK1_DYRK1A_ST	P10636	MAPT	Q13627	DYRK1A	S428	A430V	430	Missense	proximal	2	no	43.557	42.386	EPSD	TCGA;ICGC;COSMIC	34.163	Down-regulation
CMGC_DYRK_DYRK1_DYRK1A_ST	P10636	MAPT	Q13627	DYRK1A	S438	P436T	436	Missense	proximal	-2	no	58.880	53.644	EPSD	TCGA;ICGC;COSMIC	34.163	Down-regulation
CMGC_DYRK_DYRK1_DYRK1A_ST	P10636	MAPT	Q13627	DYRK1A	S438	P436L	436	Missense	proximal	-2	no	58.880	45.153	EPSD	TCGA;ICGC;COSMIC	34.163	Down-regulation
CMGC_DYRK_DYRK1_DYRK1A_ST	P10636	MAPT	Q13627	DYRK1A	S438	K440E	440	Missense	proximal	2	no	58.880	58.572	EPSD	TCGA;ICGC;COSMIC	34.163	Down-regulation
CMGC_DYRK_DYRK1_DYRK1A_ST	P10636	MAPT	Q13627	DYRK1A	S438	S443F	443	Missense	distal	5	no	58.880	54.695	EPSD	TCGA;ICGC;COSMIC	34.163	Down-regulation
CMGC_DYRK_DYRK1_DYRK1A_ST	P10636	MAPT	Q13627	DYRK1A	S438	V431L	431	Missense	distal	-7	no	58.880	58.751	EPSD	TCGA;ICGC;COSMIC	34.163	Down-regulation
CMGC_DYRK_DYRK1_DYRK1A_ST	P10636	MAPT	Q13627	DYRK1A	S438	S444F	444	Missense	distal	6	no	58.880	58.957	EPSD	TCGA;ICGC	34.163	Up-regulation
CMGC_DYRK_DYRK1_DYRK1A_ST	P10636	MAPT	Q13627	DYRK1A	T492	A485T	485	Missense	distal	-7	no	45.275	44.677	EPSD	TCGA;COSMIC;GDSC;CCLE	34.163	Down-regulation
CMGC_DYRK_DYRK1_DYRK1A_ST	P10636	MAPT	Q13627	DYRK1A	T492	P493Q	493	Missense	proximal	1	no	45.275	32.611	EPSD	TCGA;COSMIC	34.163	Loss
CMGC_DYRK_DYRK1_DYRK1A_ST	P10636	MAPT	Q13627	DYRK1A	T498	P493Q	493	Missense	distal	-5	no	54.267	53.590	EPSD	TCGA;COSMIC	34.163	Down-regulation
CMGC_DYRK_DYRK1_DYRK1A_ST	P49418	AMPH	Q13627	DYRK1A	T34	E40K	40	Missense	distal	6	no	36.276	36.328	EPSD	TCGA;ICGC;COSMIC;GDSC;CCLE	34.163	Up-regulation
CMGC_DYRK_DYRK1_DYRK1A_ST	P49418	AMPH	Q13627	DYRK1A	T34	E37K	37	Missense	distal	3	no	36.276	36.262	EPSD	TCGA;ICGC;COSMIC	34.163	Down-regulation
CMGC_DYRK_DYRK1_DYRK1A_ST	P49418	AMPH	Q13627	DYRK1A	T34	A31D	31	Missense	distal	-3	no	36.276	35.336	EPSD	TCGA;ICGC	34.163	Down-regulation
CMGC_DYRK_DYRK1_DYRK1A_ST	P49418	AMPH	Q13627	DYRK1A	T260	E265K	265	Missense	distal	5	no	38.916	38.930	EPSD	TCGA;ICGC;COSMIC	34.163	Up-regulation
CMGC_DYRK_DYRK1_DYRK1A_ST	P49418	AMPH	Q13627	DYRK1A	T260	P263L	263	Missense	distal	3	no	38.916	38.923	EPSD	TCGA;ICGC;COSMIC	34.163	Up-regulation
CMGC_DYRK_DYRK1_DYRK1A_ST	P49418	AMPH	Q13627	DYRK1A	T260	P264L	264	Missense	distal	4	no	38.916	40.963	EPSD	TCGA	34.163	Up-regulation
CMGC_DYRK_DYRK1_DYRK1A_ST	P49418	AMPH	Q13627	DYRK1A	T260	A258V	258	Missense	proximal	-2	no	38.916	37.008	EPSD	TCGA;ICGC;COSMIC	34.163	Down-regulation
CMGC_DYRK_DYRK1_DYRK1A_ST	P49418	AMPH	Q13627	DYRK1A	T260	R256H	256	Missense	distal	-4	no	38.916	38.900	EPSD	TCGA;ICGC;COSMIC	34.163	Down-regulation
CMGC_DYRK_DYRK1_DYRK1A_ST	P49418	AMPH	Q13627	DYRK1A	T260	L255P	255	Missense	distal	-5	no	38.916	40.352	EPSD	TCGA;ICGC;COSMIC	34.163	Up-regulation
CMGC_DYRK_DYRK1_DYRK1A_ST	P49418	AMPH	Q13627	DYRK1A	S262	E265K	265	Missense	distal	3	no	45.398	45.385	EPSD	TCGA;ICGC;COSMIC	34.163	Down-regulation
CMGC_DYRK_DYRK1_DYRK1A_ST	P49418	AMPH	Q13627	DYRK1A	S262	P263L	263	Missense	proximal	1	no	45.398	3.067	EPSD	TCGA;ICGC;COSMIC	34.163	Loss
CMGC_DYRK_DYRK1_DYRK1A_ST	P49418	AMPH	Q13627	DYRK1A	S262	P264L	264	Missense	proximal	2	no	45.398	44.896	EPSD	TCGA	34.163	Down-regulation
CMGC_DYRK_DYRK1_DYRK1A_ST	P49418	AMPH	Q13627	DYRK1A	S262	A258V	258	Missense	distal	-4	no	45.398	45.358	EPSD	TCGA;ICGC;COSMIC	34.163	Down-regulation
CMGC_DYRK_DYRK1_DYRK1A_ST	P49418	AMPH	Q13627	DYRK1A	S262	R256H	256	Missense	distal	-6	no	45.398	44.781	EPSD	TCGA;ICGC;COSMIC	34.163	Down-regulation
CMGC_DYRK_DYRK1_DYRK1A_ST	P49418	AMPH	Q13627	DYRK1A	S262	L255P	255	Missense	distal	-7	no	45.398	44.396	EPSD	TCGA;ICGC;COSMIC	34.163	Down-regulation
CMGC_DYRK_DYRK1_DYRK1A_ST	P49418	AMPH	Q13627	DYRK1A	S272	E265K	265	Missense	distal	-7	no	34.885	35.125	EPSD	TCGA;ICGC;COSMIC	34.163	Up-regulation
CMGC_DYRK_DYRK1_DYRK1A_ST	P49418	AMPH	Q13627	DYRK1A	S272	P277L	277	Missense	distal	5	no	34.885	34.000	EPSD	TCGA;ICGC;COSMIC	34.163	Loss
CMGC_DYRK_DYRK1_DYRK1A_ST	P49418	AMPH	Q13627	DYRK1A	S285	R292W	292	Missense	distal	7	no	36.285	40.083	EPSD	TCGA;ICGC;COSMIC	34.163	Up-regulation
CMGC_DYRK_DYRK1_DYRK1A_ST	P49418	AMPH	Q13627	DYRK1A	S285	R290W	290	Missense	distal	5	no	36.285	32.484	EPSD	TCGA;ICGC;COSMIC	34.163	Loss
CMGC_DYRK_DYRK1_DYRK1A_ST	P49418	AMPH	Q13627	DYRK1A	S285	R290Q	290	Missense	distal	5	no	36.285	37.276	EPSD	TCGA;ICGC;COSMIC	34.163	Up-regulation
CMGC_DYRK_DYRK1_DYRK1A_ST	P49418	AMPH	Q13627	DYRK1A	S285	A287T	287	Missense	proximal	2	no	36.285	35.725	EPSD	TCGA;ICGC;COSMIC	34.163	Down-regulation
CMGC_DYRK_DYRK1_DYRK1A_ST	P49418	AMPH	Q13627	DYRK1A	S285	S285Y	285	Missense	central	0	yes	36.285	0.000	EPSD	TCGA;ICGC;COSMIC	34.163	Loss
CMGC_DYRK_DYRK1_DYRK1A_ST	P49418	AMPH	Q13627	DYRK1A	S285	A282V	282	Missense	distal	-3	no	36.285	41.431	EPSD	TCGA;ICGC	34.163	Up-regulation
CMGC_DYRK_DYRK1_DYRK1A_ST	P49418	AMPH	Q13627	DYRK1A	S293	R292W	292	Missense	proximal	-1	no	65.700	66.856	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	34.163	Up-regulation
CMGC_DYRK_DYRK1_DYRK1A_ST	P49418	AMPH	Q13627	DYRK1A	S293	R290W	290	Missense	distal	-3	no	65.700	40.884	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	34.163	Down-regulation
CMGC_DYRK_DYRK1_DYRK1A_ST	P49418	AMPH	Q13627	DYRK1A	S293	R290Q	290	Missense	distal	-3	no	65.700	51.948	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	34.163	Down-regulation
CMGC_DYRK_DYRK1_DYRK1A_ST	P49418	AMPH	Q13627	DYRK1A	S293	A287T	287	Missense	distal	-6	no	65.700	65.361	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	34.163	Down-regulation
CMGC_DYRK_DYRK1_DYRK1A_ST	P49418	AMPH	Q13627	DYRK1A	S293	G300R	300	Missense	distal	7	no	65.700	64.189	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	34.163	Down-regulation
CMGC_DYRK_DYRK1_DYRK1A_ST	P49418	AMPH	Q13627	DYRK1A	S295	P302S	302	Missense	distal	7	no	53.995	53.499	EPSD;PhosphoSitePlus	TCGA	34.163	Down-regulation
CMGC_DYRK_DYRK1_DYRK1A_ST	P49418	AMPH	Q13627	DYRK1A	S295	R292W	292	Missense	distal	-3	no	53.995	29.179	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	34.163	Loss
CMGC_DYRK_DYRK1_DYRK1A_ST	P49418	AMPH	Q13627	DYRK1A	S295	R290W	290	Missense	distal	-5	no	53.995	51.738	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	34.163	Down-regulation
CMGC_DYRK_DYRK1_DYRK1A_ST	P49418	AMPH	Q13627	DYRK1A	S295	R290Q	290	Missense	distal	-5	no	53.995	52.843	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	34.163	Down-regulation
CMGC_DYRK_DYRK1_DYRK1A_ST	P49418	AMPH	Q13627	DYRK1A	S295	G300R	300	Missense	distal	5	no	53.995	54.342	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	34.163	Up-regulation
CMGC_DYRK_DYRK1_DYRK1A_ST	P49418	AMPH	Q13627	DYRK1A	T310	Q317K	317	Missense	distal	7	no	53.226	54.924	PhosphoSitePlus;EPSD	TCGA;ICGC;COSMIC	34.163	Up-regulation
CMGC_DYRK_DYRK1_DYRK1A_ST	P49418	AMPH	Q13627	DYRK1A	T310	K308N	308	Missense	proximal	-2	no	53.226	36.239	PhosphoSitePlus;EPSD	TCGA;ICGC;COSMIC	34.163	Down-regulation
CMGC_DYRK_DYRK1_DYRK1A_ST	P49418	AMPH	Q13627	DYRK1A	T310	P304S	304	Missense	distal	-6	no	53.226	53.929	PhosphoSitePlus;EPSD	TCGA;ICGC;COSMIC	34.163	Up-regulation
CMGC_DYRK_DYRK1_DYRK1A_ST	P49418	AMPH	Q13627	DYRK1A	T310	E314K	314	Missense	distal	4	no	53.226	52.868	PhosphoSitePlus;EPSD	TCGA;ICGC;COSMIC	34.163	Down-regulation
CMGC_DYRK_DYRK1_DYRK1A_ST	P49418	AMPH	Q13627	DYRK1A	T312	Q317K	317	Missense	distal	5	no	51.793	50.758	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	34.163	Down-regulation
CMGC_DYRK_DYRK1_DYRK1A_ST	P49418	AMPH	Q13627	DYRK1A	T312	K308N	308	Missense	distal	-4	no	51.793	51.819	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	34.163	Up-regulation
CMGC_DYRK_DYRK1_DYRK1A_ST	P49418	AMPH	Q13627	DYRK1A	T312	E314K	314	Missense	proximal	2	no	51.793	52.101	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	34.163	Up-regulation
CMGC_DYRK_DYRK1_DYRK1A_ST	P49418	AMPH	Q13627	DYRK1A	T312	T310S	310	Missense	proximal	-2	no	51.793	52.093	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	34.163	Up-regulation
CMGC_DYRK_DYRK1_DYRK1A_ST	P49418	AMPH	Q13627	DYRK1A	T445	A447T	447	Missense	proximal	2	no	45.689	45.128	EPSD	TCGA;ICGC;COSMIC	34.163	Down-regulation
CMGC_DYRK_DYRK1_DYRK1A_ST	P49418	AMPH	Q13627	DYRK1A	T445	A443S	443	Missense	proximal	-2	no	45.689	44.642	EPSD	TCGA;ICGC;COSMIC	34.163	Down-regulation
CMGC_DYRK_DYRK1_DYRK1A_ST	P49418	AMPH	Q13627	DYRK1A	T498	P500H	500	Missense	proximal	2	no	35.201	34.479	EPSD	TCGA;COSMIC	34.163	Down-regulation
CMGC_DYRK_DYRK1_DYRK1A_ST	P49418	AMPH	Q13627	DYRK1A	T498	G502V	502	Missense	distal	4	no	35.201	37.704	EPSD	TCGA;COSMIC	34.163	Up-regulation
CMGC_DYRK_DYRK1_DYRK1A_ST	P49418	AMPH	Q13627	DYRK1A	T498	G502R	502	Missense	distal	4	no	35.201	34.117	EPSD	TCGA;COSMIC	34.163	Loss
CMGC_DYRK_DYRK1_DYRK1A_ST	P49418	AMPH	Q13627	DYRK1A	T498	G502W	502	Missense	distal	4	no	35.201	37.337	EPSD	TCGA;ICGC;COSMIC	34.163	Up-regulation
CMGC_DYRK_DYRK1_DYRK1A_ST	P49418	AMPH	Q13627	DYRK1A	T498	P500S	500	Missense	proximal	2	no	35.201	35.101	EPSD	TCGA;COSMIC;GDSC;CCLE	34.163	Down-regulation
CMGC_DYRK_DYRK1_DYRK1A_ST	P49418	AMPH	Q13627	DYRK1A	T498	A497T	497	Missense	proximal	-1	no	35.201	34.499	EPSD	TCGA;COSMIC	34.163	Down-regulation
CMGC_DYRK_DYRK1_DYRK1A_ST	P49418	AMPH	Q13627	DYRK1A	T498	A494V	494	Missense	distal	-4	no	35.201	35.162	EPSD	TCGA;COSMIC	34.163	Down-regulation
CMGC_DYRK_DYRK1_DYRK1A_ST	P53805	RCAN1	Q13627	DYRK1A	S167	S167Y	167	Missense	central	0	yes	60.157	0.000	EPSD;PhosphoSitePlus	TCGA;COSMIC	34.163	Loss
CMGC_DYRK_DYRK1_DYRK1A_ST	P53805	RCAN1	Q13627	DYRK1A	S167	L161Q	161	Missense	distal	-6	no	60.157	59.953	EPSD;PhosphoSitePlus	TCGA;COSMIC	34.163	Down-regulation
CMGC_DYRK_DYRK1_DYRK1A_ST	P53805	RCAN1	Q13627	DYRK1A	T179	E176G	176	Missense	distal	-3	no	26.224	35.368	EPSD	TCGA;COSMIC	34.163	Gain
CMGC_DYRK_DYRK1_DYRK1A_ST	P53805	RCAN1	Q13627	DYRK1A	S191	Y188F	188	Missense	distal	-3	no	34.519	24.744	EPSD	TCGA;COSMIC	34.163	Loss
CMGC_DYRK_DYRK1_DYRK1A_ST	P53805	RCAN1	Q13627	DYRK1A	S191	G194W	194	Missense	distal	3	no	34.519	34.309	EPSD	TCGA;COSMIC	34.163	Down-regulation
CMGC_DYRK_DYRK1_DYRK1A_ST	P53805	RCAN1	Q13627	DYRK1A	S191	E197K	197	Missense	distal	6	no	34.519	34.572	EPSD	TCGA;COSMIC	34.163	Up-regulation
CMGC_DYRK_DYRK1_DYRK1A_ST	P24928	POLR2A	Q13627	DYRK1A	S27	F23L	23	Missense	distal	-4	no	52.809	52.830	EPSD	TCGA;ICGC;COSMIC	34.163	Up-regulation
CMGC_DYRK_DYRK1_DYRK1A_ST	P24928	POLR2A	Q13627	DYRK1A	S35	S35Y	35	Missense	central	0	yes	46.038	0.000	EPSD	TCGA;ICGC;COSMIC	34.163	Loss
CMGC_DYRK_DYRK1_DYRK1A_ST	P24928	POLR2A	Q13627	DYRK1A	S35	T37M	37	Missense	proximal	2	no	46.038	45.224	EPSD	TCGA;ICGC;COSMIC	34.163	Down-regulation
CMGC_DYRK_DYRK1_DYRK1A_ST	P24928	POLR2A	Q13627	DYRK1A	S35	E38D	38	Missense	distal	3	no	46.038	45.857	EPSD	TCGA;ICGC	34.163	Down-regulation
CMGC_DYRK_DYRK1_DYRK1A_ST	P24928	POLR2A	Q13627	DYRK1A	T549	D552N	552	Missense	distal	3	no	45.971	46.052	EPSD	TCGA;ICGC;COSMIC	34.163	Up-regulation
CMGC_DYRK_DYRK1_DYRK1A_ST	P24928	POLR2A	Q13627	DYRK1A	T549	V553I	553	Missense	distal	4	no	45.971	46.407	EPSD	TCGA;ICGC;COSMIC	34.163	Up-regulation
CMGC_DYRK_DYRK1_DYRK1A_ST	P24928	POLR2A	Q13627	DYRK1A	T549	R546H	546	Missense	distal	-3	no	45.971	30.639	EPSD	TCGA;ICGC;COSMIC	34.163	Loss
CMGC_DYRK_DYRK1_DYRK1A_ST	P24928	POLR2A	Q13627	DYRK1A	T857	R863L	863	Missense	distal	6	no	36.096	36.220	EPSD	TCGA;ICGC	34.163	Up-regulation
CMGC_DYRK_DYRK1_DYRK1A_ST	P24928	POLR2A	Q13627	DYRK1A	S1348	R1345W	1345	Missense	distal	-3	no	34.381	9.566	EPSD	TCGA;ICGC	34.163	Loss
CMGC_DYRK_DYRK1_DYRK1A_ST	P24928	POLR2A	Q13627	DYRK1A	T1424	R1421H	1421	Missense	distal	-3	no	42.528	27.196	EPSD	TCGA;ICGC	34.163	Loss
CMGC_DYRK_DYRK1_DYRK1A_ST	P24928	POLR2A	Q13627	DYRK1A	S1514	M1510L	1510	Missense	distal	-4	no	40.812	40.836	EPSD	TCGA;ICGC	34.163	Up-regulation
CMGC_DYRK_DYRK1_DYRK1A_ST	P24928	POLR2A	Q13627	DYRK1A	S1514	A1516V	1516	Missense	proximal	2	no	40.812	39.641	EPSD	TCGA;ICGC	34.163	Down-regulation
CMGC_DYRK_DYRK1_DYRK1A_ST	P24928	POLR2A	Q13627	DYRK1A	S1514	M1517V	1517	Missense	distal	3	no	40.812	40.675	EPSD	TCGA;ICGC	34.163	Down-regulation
CMGC_DYRK_DYRK1_DYRK1A_ST	P24928	POLR2A	Q13627	DYRK1A	T1518	A1516V	1516	Missense	proximal	-2	no	41.421	39.513	EPSD	TCGA;ICGC	34.163	Down-regulation
CMGC_DYRK_DYRK1_DYRK1A_ST	P24928	POLR2A	Q13627	DYRK1A	T1518	M1517V	1517	Missense	proximal	-1	no	41.421	40.621	EPSD	TCGA;ICGC	34.163	Down-regulation
CMGC_DYRK_DYRK1_DYRK1A_ST	P24928	POLR2A	Q13627	DYRK1A	S1532	A1527V	1527	Missense	distal	-5	no	38.458	38.890	EPSD	TCGA;ICGC	34.163	Up-regulation
CMGC_DYRK_DYRK1_DYRK1A_ST	P24928	POLR2A	Q13627	DYRK1A	S1571	P1572L	1572	Missense	proximal	1	no	38.122	-4.209	EPSD	TCGA;ICGC	34.163	Loss
CMGC_DYRK_DYRK1_DYRK1A_ST	P24928	POLR2A	Q13627	DYRK1A	S1571	G1570S	1570	Missense	proximal	-1	no	38.122	37.550	EPSD	TCGA;ICGC	34.163	Down-regulation
CMGC_DYRK_DYRK1_DYRK1A_ST	P24928	POLR2A	Q13627	DYRK1A	S1574	P1572L	1572	Missense	proximal	-2	no	45.919	32.192	EPSD	TCGA;ICGC	34.163	Loss
CMGC_DYRK_DYRK1_DYRK1A_ST	P24928	POLR2A	Q13627	DYRK1A	S1574	G1570S	1570	Missense	distal	-4	no	45.919	45.941	EPSD	TCGA;ICGC	34.163	Up-regulation
CMGC_DYRK_DYRK1_DYRK1A_ST	P24928	POLR2A	Q13627	DYRK1A	S1590	P1591L	1591	Missense	proximal	1	no	35.461	-6.870	EPSD	TCGA;ICGC	34.163	Loss
CMGC_DYRK_DYRK1_DYRK1A_ST	P24928	POLR2A	Q13627	DYRK1A	S1597	R1603H	1603	Missense	distal	6	no	37.838	37.967	EPSD	TCGA;ICGC	34.163	Up-regulation
CMGC_DYRK_DYRK1_DYRK1A_ST	P24928	POLR2A	Q13627	DYRK1A	S1597	P1591L	1591	Missense	distal	-6	no	37.838	37.896	EPSD	TCGA;ICGC	34.163	Up-regulation
CMGC_DYRK_DYRK1_DYRK1A_ST	P24928	POLR2A	Q13627	DYRK1A	S1619	T1625A	1625	Missense	distal	6	no	51.765	51.810	EPSD;PhosphoSitePlus	TCGA;ICGC	34.163	Up-regulation
CMGC_DYRK_DYRK1_DYRK1A_ST	P24928	POLR2A	Q13627	DYRK1A	S1626	T1625A	1625	Missense	proximal	-1	no	35.541	36.243	EPSD	TCGA;ICGC	34.163	Up-regulation
CMGC_DYRK_DYRK1_DYRK1A_ST	P24928	POLR2A	Q13627	DYRK1A	S1626	S1630Y	1630	Missense	distal	4	no	35.541	37.177	EPSD	TCGA	34.163	Up-regulation
CMGC_DYRK_DYRK1_DYRK1A_ST	P24928	POLR2A	Q13627	DYRK1A	S1626	P1631S	1631	Missense	distal	5	no	35.541	35.602	EPSD	TCGA;ICGC	34.163	Up-regulation
CMGC_DYRK_DYRK1_DYRK1A_ST	P24928	POLR2A	Q13627	DYRK1A	S1626	P1631L	1631	Missense	distal	5	no	35.541	34.655	EPSD	TCGA;ICGC	34.163	Down-regulation
CMGC_DYRK_DYRK1_DYRK1A_ST	P24928	POLR2A	Q13627	DYRK1A	S1675	S1677N	1677	Missense	proximal	2	no	37.504	36.424	EPSD	TCGA;ICGC	34.163	Down-regulation
CMGC_DYRK_DYRK1_DYRK1A_ST	P24928	POLR2A	Q13627	DYRK1A	S1682	S1677N	1677	Missense	distal	-5	no	37.504	36.133	EPSD	TCGA;ICGC	34.163	Down-regulation
CMGC_DYRK_DYRK1_DYRK1A_ST	P24928	POLR2A	Q13627	DYRK1A	S1689	T1695M	1695	Missense	distal	6	no	37.504	37.669	EPSD	TCGA;ICGC	34.163	Up-regulation
CMGC_DYRK_DYRK1_DYRK1A_ST	P24928	POLR2A	Q13627	DYRK1A	S1696	T1702I	1702	Missense	distal	6	no	37.504	37.686	EPSD	TCGA;ICGC	34.163	Up-regulation
CMGC_DYRK_DYRK1_DYRK1A_ST	P24928	POLR2A	Q13627	DYRK1A	S1696	T1702S	1702	Missense	distal	6	no	37.504	37.516	EPSD	TCGA;ICGC	34.163	Up-regulation
CMGC_DYRK_DYRK1_DYRK1A_ST	P24928	POLR2A	Q13627	DYRK1A	S1696	T1695M	1695	Missense	proximal	-1	no	37.504	39.550	EPSD	TCGA;ICGC	34.163	Up-regulation
CMGC_DYRK_DYRK1_DYRK1A_ST	P24928	POLR2A	Q13627	DYRK1A	S1696	S1700L	1700	Missense	distal	4	no	37.504	39.354	EPSD	TCGA;ICGC	34.163	Up-regulation
CMGC_DYRK_DYRK1_DYRK1A_ST	P24928	POLR2A	Q13627	DYRK1A	S1703	T1702I	1702	Missense	proximal	-1	no	37.504	38.830	EPSD	TCGA;ICGC	34.163	Up-regulation
CMGC_DYRK_DYRK1_DYRK1A_ST	P24928	POLR2A	Q13627	DYRK1A	S1703	T1702S	1702	Missense	proximal	-1	no	37.504	37.974	EPSD	TCGA;ICGC	34.163	Up-regulation
CMGC_DYRK_DYRK1_DYRK1A_ST	P24928	POLR2A	Q13627	DYRK1A	S1703	S1700L	1700	Missense	distal	-3	no	37.504	32.739	EPSD	TCGA;ICGC	34.163	Loss
CMGC_DYRK_DYRK1_DYRK1A_ST	P24928	POLR2A	Q13627	DYRK1A	S1731	P1732L	1732	Missense	proximal	1	no	42.421	0.090	EPSD	TCGA;ICGC;CCLE	34.163	Loss
CMGC_DYRK_DYRK1_DYRK1A_ST	P24928	POLR2A	Q13627	DYRK1A	S1731	S1735A	1735	Missense	distal	4	no	42.421	42.881	EPSD	TCGA;ICGC	34.163	Up-regulation
CMGC_DYRK_DYRK1_DYRK1A_ST	P24928	POLR2A	Q13627	DYRK1A	S1738	T1744I	1744	Missense	distal	6	no	41.106	41.287	EPSD	TCGA;ICGC	34.163	Up-regulation
CMGC_DYRK_DYRK1_DYRK1A_ST	P24928	POLR2A	Q13627	DYRK1A	S1738	S1745N	1745	Missense	distal	7	no	41.106	44.425	EPSD	TCGA;ICGC	34.163	Up-regulation
CMGC_DYRK_DYRK1_DYRK1A_ST	P24928	POLR2A	Q13627	DYRK1A	S1738	P1732L	1732	Missense	distal	-6	no	41.106	41.163	EPSD	TCGA;ICGC;CCLE	34.163	Up-regulation
CMGC_DYRK_DYRK1_DYRK1A_ST	P24928	POLR2A	Q13627	DYRK1A	S1738	S1735A	1735	Missense	distal	-3	no	41.106	35.279	EPSD	TCGA;ICGC	34.163	Down-regulation
CMGC_DYRK_DYRK1_DYRK1A_ST	P24928	POLR2A	Q13627	DYRK1A	S1766	P1764S	1764	Missense	proximal	-2	no	36.827	31.891	EPSD	TCGA;ICGC	34.163	Loss
CMGC_DYRK_DYRK1_DYRK1A_ST	P24928	POLR2A	Q13627	DYRK1A	S1766	T1772I	1772	Missense	distal	6	no	36.827	37.009	EPSD	TCGA;ICGC	34.163	Up-regulation
CMGC_DYRK_DYRK1_DYRK1A_ST	P24928	POLR2A	Q13627	DYRK1A	S1794	S1787F	1787	Missense	distal	-7	no	36.483	37.585	EPSD	TCGA;ICGC	34.163	Up-regulation
CMGC_DYRK_DYRK1_DYRK1A_ST	P24928	POLR2A	Q13627	DYRK1A	T1812	P1816A	1816	Missense	distal	4	no	40.725	41.382	EPSD	TCGA;ICGC	34.163	Up-regulation
CMGC_DYRK_DYRK1_DYRK1A_ST	P24928	POLR2A	Q13627	DYRK1A	T1812	Y1818C	1818	Missense	distal	6	no	40.725	40.693	EPSD	TCGA	34.163	Down-regulation
CMGC_DYRK_DYRK1_DYRK1A_ST	P24928	POLR2A	Q13627	DYRK1A	T1812	P1809S	1809	Missense	distal	-3	no	40.725	43.497	EPSD	TCGA;ICGC	34.163	Up-regulation
CMGC_DYRK_DYRK1_DYRK1A_ST	P24928	POLR2A	Q13627	DYRK1A	T1819	P1816A	1816	Missense	distal	-3	no	36.765	33.710	EPSD	TCGA;ICGC	34.163	Loss
CMGC_DYRK_DYRK1_DYRK1A_ST	P24928	POLR2A	Q13627	DYRK1A	T1819	Y1818C	1818	Missense	proximal	-1	no	36.765	36.440	EPSD	TCGA	34.163	Down-regulation
CMGC_DYRK_DYRK1_DYRK1A_ST	P24928	POLR2A	Q13627	DYRK1A	T1840	S1845P	1845	Missense	distal	5	no	42.348	42.287	EPSD	TCGA;GDSC;CCLE	34.163	Down-regulation
CMGC_DYRK_DYRK1_DYRK1A_ST	P24928	POLR2A	Q13627	DYRK1A	T1840	S1845Y	1845	Missense	distal	5	no	42.348	37.705	EPSD	TCGA;ICGC	34.163	Down-regulation
CMGC_DYRK_DYRK1_DYRK1A_ST	P24928	POLR2A	Q13627	DYRK1A	S1847	S1845P	1845	Missense	proximal	-2	no	40.415	45.352	EPSD	TCGA;GDSC;CCLE	34.163	Up-regulation
CMGC_DYRK_DYRK1_DYRK1A_ST	P24928	POLR2A	Q13627	DYRK1A	S1847	S1845Y	1845	Missense	proximal	-2	no	40.415	38.853	EPSD	TCGA;ICGC	34.163	Down-regulation
CMGC_DYRK_DYRK1_DYRK1A_ST	P24928	POLR2A	Q13627	DYRK1A	S1850	S1845P	1845	Missense	distal	-5	no	44.410	45.165	EPSD	TCGA;GDSC;CCLE	34.163	Up-regulation
CMGC_DYRK_DYRK1_DYRK1A_ST	P24928	POLR2A	Q13627	DYRK1A	S1850	S1857C	1857	Missense	distal	7	no	44.410	47.166	EPSD	TCGA;ICGC	34.163	Up-regulation
CMGC_DYRK_DYRK1_DYRK1A_ST	P24928	POLR2A	Q13627	DYRK1A	S1850	S1845Y	1845	Missense	distal	-5	no	44.410	44.062	EPSD	TCGA;ICGC	34.163	Down-regulation
CMGC_DYRK_DYRK1_DYRK1A_ST	P24928	POLR2A	Q13627	DYRK1A	S1850	S1857F	1857	Missense	distal	7	no	44.410	47.807	EPSD	TCGA	34.163	Up-regulation
CMGC_DYRK_DYRK1_DYRK1A_ST	P24928	POLR2A	Q13627	DYRK1A	T1854	S1857C	1857	Missense	distal	3	no	40.096	39.715	EPSD	TCGA;ICGC	34.163	Down-regulation
CMGC_DYRK_DYRK1_DYRK1A_ST	P24928	POLR2A	Q13627	DYRK1A	T1854	S1857F	1857	Missense	distal	3	no	40.096	39.539	EPSD	TCGA	34.163	Down-regulation
CMGC_DYRK_DYRK1_DYRK1A_ST	P24928	POLR2A	Q13627	DYRK1A	S1861	S1857C	1857	Missense	distal	-4	no	37.943	37.930	EPSD	TCGA;ICGC	34.163	Down-regulation
CMGC_DYRK_DYRK1_DYRK1A_ST	P24928	POLR2A	Q13627	DYRK1A	S1861	S1857F	1857	Missense	distal	-4	no	37.943	37.918	EPSD	TCGA	34.163	Down-regulation
CMGC_DYRK_DYRK1_DYRK1A_ST	P24928	POLR2A	Q13627	DYRK1A	S1864	S1857C	1857	Missense	distal	-7	no	45.115	46.014	EPSD	TCGA;ICGC	34.163	Up-regulation
CMGC_DYRK_DYRK1_DYRK1A_ST	P24928	POLR2A	Q13627	DYRK1A	S1864	S1857F	1857	Missense	distal	-7	no	45.115	46.218	EPSD	TCGA	34.163	Up-regulation
CMGC_DYRK_DYRK1_DYRK1A_ST	P24928	POLR2A	Q13627	DYRK1A	S1868	Y1874H	1874	Missense	distal	6	no	42.674	42.625	EPSD	TCGA;ICGC	34.163	Down-regulation
CMGC_DYRK_DYRK1_DYRK1A_ST	P24928	POLR2A	Q13627	DYRK1A	S1868	S1875L	1875	Missense	distal	7	no	42.674	44.829	EPSD	TCGA;ICGC	34.163	Up-regulation
CMGC_DYRK_DYRK1_DYRK1A_ST	P24928	POLR2A	Q13627	DYRK1A	S1871	Y1874H	1874	Missense	distal	3	no	47.860	47.840	EPSD	TCGA;ICGC	34.163	Down-regulation
CMGC_DYRK_DYRK1_DYRK1A_ST	P24928	POLR2A	Q13627	DYRK1A	S1871	S1875L	1875	Missense	distal	4	no	47.860	49.710	EPSD	TCGA;ICGC	34.163	Up-regulation
CMGC_DYRK_DYRK1_DYRK1A_ST	P24928	POLR2A	Q13627	DYRK1A	S1875	Y1874H	1874	Missense	proximal	-1	no	37.343	35.882	EPSD	TCGA;ICGC	34.163	Down-regulation
CMGC_DYRK_DYRK1_DYRK1A_ST	P24928	POLR2A	Q13627	DYRK1A	S1875	S1875L	1875	Missense	central	0	yes	37.343	0.000	EPSD	TCGA;ICGC	34.163	Loss
CMGC_DYRK_DYRK1_DYRK1A_ST	P24928	POLR2A	Q13627	DYRK1A	S1878	Y1874H	1874	Missense	distal	-4	no	40.632	40.659	EPSD	TCGA;ICGC	34.163	Up-regulation
CMGC_DYRK_DYRK1_DYRK1A_ST	P24928	POLR2A	Q13627	DYRK1A	S1878	S1875L	1875	Missense	distal	-3	no	40.632	35.867	EPSD	TCGA;ICGC	34.163	Down-regulation
CMGC_DYRK_DYRK1_DYRK1A_ST	P24928	POLR2A	Q13627	DYRK1A	S1882	S1875L	1875	Missense	distal	-7	no	37.254	38.319	EPSD	TCGA;ICGC	34.163	Up-regulation
CMGC_DYRK_DYRK1_DYRK1A_ST	P24928	POLR2A	Q13627	DYRK1A	S1882	K1887N	1887	Missense	distal	5	no	37.254	32.790	EPSD	TCGA;ICGC	34.163	Loss
CMGC_DYRK_DYRK1_DYRK1A_ST	P24928	POLR2A	Q13627	DYRK1A	T1885	K1887N	1887	Missense	proximal	2	no	43.317	41.729	EPSD	TCGA;ICGC	34.163	Down-regulation
CMGC_DYRK_DYRK1_DYRK1A_ST	P24928	POLR2A	Q13627	DYRK1A	S1889	S1896F	1896	Missense	distal	7	no	43.194	46.592	EPSD	TCGA;ICGC	34.163	Up-regulation
CMGC_DYRK_DYRK1_DYRK1A_ST	P24928	POLR2A	Q13627	DYRK1A	S1889	K1887N	1887	Missense	proximal	-2	no	43.194	26.208	EPSD	TCGA;ICGC	34.163	Loss
CMGC_DYRK_DYRK1_DYRK1A_ST	P24928	POLR2A	Q13627	DYRK1A	S1892	T1898A	1898	Missense	distal	6	no	39.918	39.964	EPSD	TCGA;ICGC	34.163	Up-regulation
CMGC_DYRK_DYRK1_DYRK1A_ST	P24928	POLR2A	Q13627	DYRK1A	S1892	S1896F	1896	Missense	distal	4	no	39.918	42.570	EPSD	TCGA;ICGC	34.163	Up-regulation
CMGC_DYRK_DYRK1_DYRK1A_ST	P24928	POLR2A	Q13627	DYRK1A	S1892	K1887N	1887	Missense	distal	-5	no	39.918	38.481	EPSD	TCGA;ICGC	34.163	Down-regulation
CMGC_DYRK_DYRK1_DYRK1A_ST	P24928	POLR2A	Q13627	DYRK1A	S1896	T1898A	1898	Missense	proximal	2	no	37.561	38.122	EPSD	TCGA;ICGC	34.163	Up-regulation
CMGC_DYRK_DYRK1_DYRK1A_ST	P24928	POLR2A	Q13627	DYRK1A	S1896	S1896F	1896	Missense	central	0	yes	37.561	0.000	EPSD	TCGA;ICGC	34.163	Loss
CMGC_DYRK_DYRK1_DYRK1A_ST	P24928	POLR2A	Q13627	DYRK1A	S1899	T1898A	1898	Missense	proximal	-1	no	42.757	43.459	EPSD	TCGA;ICGC	34.163	Up-regulation
CMGC_DYRK_DYRK1_DYRK1A_ST	P24928	POLR2A	Q13627	DYRK1A	S1899	S1896F	1896	Missense	distal	-3	no	42.757	23.584	EPSD	TCGA;ICGC	34.163	Loss
CMGC_DYRK_DYRK1_DYRK1A_ST	P24928	POLR2A	Q13627	DYRK1A	T1903	T1898A	1898	Missense	distal	-5	no	42.295	42.303	EPSD	TCGA;ICGC	34.163	Up-regulation
CMGC_DYRK_DYRK1_DYRK1A_ST	P24928	POLR2A	Q13627	DYRK1A	T1903	P1907S	1907	Missense	distal	4	no	42.295	42.492	EPSD	TCGA;ICGC	34.163	Up-regulation
CMGC_DYRK_DYRK1_DYRK1A_ST	P24928	POLR2A	Q13627	DYRK1A	T1903	S1896F	1896	Missense	distal	-7	no	42.295	43.397	EPSD	TCGA;ICGC	34.163	Up-regulation
CMGC_DYRK_DYRK1_DYRK1A_ST	P24928	POLR2A	Q13627	DYRK1A	S1910	P1907S	1907	Missense	distal	-3	no	35.690	38.462	EPSD	TCGA;ICGC	34.163	Up-regulation
CMGC_DYRK_DYRK1_DYRK1A_ST	P24928	POLR2A	Q13627	DYRK1A	S1913	P1907S	1907	Missense	distal	-6	no	40.178	40.881	EPSD	TCGA;ICGC	34.163	Up-regulation
CMGC_DYRK_DYRK1_DYRK1A_ST	P24928	POLR2A	Q13627	DYRK1A	S1924	S1931L	1931	Missense	distal	7	no	34.769	36.924	EPSD	TCGA;ICGC	34.163	Up-regulation
CMGC_DYRK_DYRK1_DYRK1A_ST	P24928	POLR2A	Q13627	DYRK1A	S1927	S1931L	1931	Missense	distal	4	no	41.494	43.345	EPSD	TCGA;ICGC	34.163	Up-regulation
CMGC_DYRK_DYRK1_DYRK1A_ST	P24928	POLR2A	Q13627	DYRK1A	S1931	S1931L	1931	Missense	central	0	yes	36.460	0.000	EPSD	TCGA;ICGC	34.163	Loss
CMGC_DYRK_DYRK1_DYRK1A_ST	P24928	POLR2A	Q13627	DYRK1A	S1934	S1931L	1931	Missense	distal	-3	no	42.628	37.862	EPSD	TCGA;ICGC	34.163	Down-regulation
CMGC_DYRK_DYRK1_DYRK1A_ST	P24928	POLR2A	Q13627	DYRK1A	T1939	S1944F	1944	Missense	distal	5	no	39.329	35.144	EPSD	TCGA;ICGC	34.163	Down-regulation
CMGC_DYRK_DYRK1_DYRK1A_ST	P24928	POLR2A	Q13627	DYRK1A	S1941	S1944F	1944	Missense	distal	3	no	36.377	35.819	EPSD	TCGA;ICGC	34.163	Down-regulation
CMGC_DYRK_DYRK1_DYRK1A_ST	P24928	POLR2A	Q13627	DYRK1A	S1944	S1944F	1944	Missense	central	0	yes	50.754	0.000	EPSD	TCGA;ICGC	34.163	Loss
CMGC_DYRK_DYRK1_DYRK1A_ST	P24928	POLR2A	Q13627	DYRK1A	S1948	S1944F	1944	Missense	distal	-4	no	34.639	34.615	EPSD	TCGA;ICGC	34.163	Down-regulation
CMGC_DYRK_DYRK1_DYRK1A_ST	P24928	POLR2A	Q13627	DYRK1A	S1951	S1944F	1944	Missense	distal	-7	no	46.557	47.659	EPSD	TCGA;ICGC	34.163	Up-regulation
CMGC_DYRK_DYRK1_DYRK1A_ST	P24928	POLR2A	Q13627	DYRK1A	S1962	I1961M	1961	Missense	proximal	-1	no	35.682	36.402	EPSD	TCGA;ICGC	34.163	Up-regulation
CMGC_DYRK_DYRK1_DYRK1A_ST	P08151	GLI1	Q13627	DYRK1A	S84	I85M	85	Missense	proximal	1	no	50.733	6.757	EPSD	TCGA;COSMIC	34.163	Loss
CMGC_DYRK_DYRK1_DYRK1A_ST	P08151	GLI1	Q13627	DYRK1A	S84	R81L	81	Missense	distal	-3	no	50.733	37.379	EPSD	TCGA;COSMIC	34.163	Down-regulation
CMGC_DYRK_DYRK1_DYRK1A_ST	P08151	GLI1	Q13627	DYRK1A	S84	S89L	89	Missense	distal	5	no	50.733	49.787	EPSD	TCGA;COSMIC	34.163	Down-regulation
CMGC_DYRK_DYRK1_DYRK1A_ST	P08151	GLI1	Q13627	DYRK1A	S84	S84P	84	Missense	central	0	yes	50.733	0.000	EPSD	TCGA;COSMIC	34.163	Loss
CMGC_DYRK_DYRK1_DYRK1A_ST	P08151	GLI1	Q13627	DYRK1A	S84	R81W	81	Missense	distal	-3	no	50.733	25.918	EPSD	TCGA;COSMIC	34.163	Loss
CMGC_DYRK_DYRK1_DYRK1A_ST	P08151	GLI1	Q13627	DYRK1A	S84	R81Q	81	Missense	distal	-3	no	50.733	36.982	EPSD	TCGA;COSMIC	34.163	Down-regulation
CMGC_DYRK_DYRK1_DYRK1A_ST	P08151	GLI1	Q13627	DYRK1A	S84	K79N	79	Missense	distal	-5	no	50.733	49.296	EPSD	TCGA;COSMIC	34.163	Down-regulation
CMGC_DYRK_DYRK1_DYRK1A_ST	P08151	GLI1	Q13627	DYRK1A	S86	S84P	84	Missense	proximal	-2	no	31.389	36.325	EPSD	TCGA;COSMIC	34.163	Gain
CMGC_DYRK_DYRK1_DYRK1A_ST	P08151	GLI1	Q13627	DYRK1A	S102	R100C	100	Missense	proximal	-2	no	38.498	25.378	EPSD	TCGA;COSMIC	34.163	Loss
CMGC_DYRK_DYRK1_DYRK1A_ST	P08151	GLI1	Q13627	DYRK1A	S102	V107L	107	Missense	distal	5	no	38.498	41.205	EPSD	TCGA;COSMIC	34.163	Up-regulation
CMGC_DYRK_DYRK1_DYRK1A_ST	P08151	GLI1	Q13627	DYRK1A	S102	T97M	97	Missense	distal	-5	no	38.498	38.238	EPSD	TCGA;COSMIC	34.163	Down-regulation
CMGC_DYRK_DYRK1_DYRK1A_ST	P08151	GLI1	Q13627	DYRK1A	S408	R405G	405	Missense	distal	-3	no	54.087	44.893	PhosphoSitePlus	TCGA;COSMIC	34.163	Down-regulation
CMGC_DYRK_DYRK1_DYRK1A_ST	P08151	GLI1	Q13627	DYRK1A	S408	R405W	405	Missense	distal	-3	no	54.087	29.271	PhosphoSitePlus	TCGA;COSMIC	34.163	Loss
CMGC_DYRK_DYRK1_DYRK1A_ST	P08151	GLI1	Q13627	DYRK1A	S538	L539P	539	Missense	proximal	1	no	4.685	47.016	EPSD	TCGA	34.163	Gain
CMGC_DYRK_DYRK1_DYRK1A_ST	P08151	GLI1	Q13627	DYRK1A	S545	R541H	541	Missense	distal	-4	no	47.505	47.489	EPSD	TCGA;COSMIC	34.163	Down-regulation
CMGC_DYRK_DYRK1_DYRK1A_ST	P08151	GLI1	Q13627	DYRK1A	S545	E540K	540	Missense	distal	-5	no	47.505	48.078	EPSD	TCGA;COSMIC	34.163	Up-regulation
CMGC_DYRK_DYRK1_DYRK1A_ST	P08151	GLI1	Q13627	DYRK1A	S545	S543N	543	Missense	proximal	-2	no	47.505	29.812	EPSD	TCGA;COSMIC	34.163	Loss
CMGC_DYRK_DYRK1_DYRK1A_ST	P08151	GLI1	Q13627	DYRK1A	S545	L539P	539	Missense	distal	-6	no	47.505	47.448	EPSD	TCGA	34.163	Down-regulation
CMGC_DYRK_DYRK1_DYRK1A_ST	P08151	GLI1	Q13627	DYRK1A	S602	S607F	607	Missense	distal	5	no	44.149	39.963	EPSD	TCGA;COSMIC	34.163	Down-regulation
CMGC_DYRK_DYRK1_DYRK1A_ST	P08151	GLI1	Q13627	DYRK1A	S640	R637Q	637	Missense	distal	-3	no	43.812	30.060	EPSD	TCGA;COSMIC	34.163	Loss
CMGC_DYRK_DYRK1_DYRK1A_ST	P08151	GLI1	Q13627	DYRK1A	S640	R638G	638	Missense	proximal	-2	no	43.812	37.117	EPSD	TCGA;COSMIC	34.163	Down-regulation
CMGC_DYRK_DYRK1_DYRK1A_ST	P08151	GLI1	Q13627	DYRK1A	S934	V936A	936	Missense	proximal	2	no	34.044	35.215	EPSD	TCGA;COSMIC	34.163	Gain
CMGC_DYRK_DYRK1_DYRK1A_ST	P08151	GLI1	Q13627	DYRK1A	S934	R940H	940	Missense	distal	6	no	34.044	34.173	EPSD	TCGA;GDSC;CCLE	34.163	Gain
CMGC_DYRK_DYRK1_DYRK1A_ST	P08151	GLI1	Q13627	DYRK1A	S937	V936A	936	Missense	proximal	-1	no	44.905	44.360	EPSD	TCGA;COSMIC	34.163	Down-regulation
CMGC_DYRK_DYRK1_DYRK1A_ST	P08151	GLI1	Q13627	DYRK1A	S937	L931M	931	Missense	distal	-6	no	44.905	44.097	EPSD	TCGA;COSMIC	34.163	Down-regulation
CMGC_DYRK_DYRK1_DYRK1A_ST	P08151	GLI1	Q13627	DYRK1A	S937	R940H	940	Missense	distal	3	no	44.905	44.745	EPSD	TCGA;GDSC;CCLE	34.163	Down-regulation
CMGC_DYRK_DYRK1_DYRK1A_ST	P08151	GLI1	Q13627	DYRK1A	S939	V936A	936	Missense	distal	-3	no	39.170	34.025	EPSD	TCGA;COSMIC	34.163	Loss
CMGC_DYRK_DYRK1_DYRK1A_ST	P08151	GLI1	Q13627	DYRK1A	S939	R940H	940	Missense	proximal	1	no	39.170	7.008	EPSD	TCGA;GDSC;CCLE	34.163	Loss
CMGC_DYRK_DYRK1_DYRK1A_ST	P08151	GLI1	Q13627	DYRK1A	S1071	S1064F	1064	Missense	distal	-7	no	34.247	35.350	EPSD	TCGA;ICGC;COSMIC	34.163	Up-regulation
CMGC_DYRK_DYRK1_DYRK1A_ST	P08151	GLI1	Q13627	DYRK1A	S1071	P1077L	1077	Missense	distal	6	no	34.247	34.319	EPSD	TCGA;COSMIC	34.163	Up-regulation
CMGC_DYRK_DYRK1_DYRK1A_ST	P08151	GLI1	Q13627	DYRK1A	S1071	G1069S	1069	Missense	proximal	-2	no	34.247	37.216	EPSD	TCGA;COSMIC	34.163	Up-regulation
CMGC_DYRK_DYRK1_DYRK1A_ST	P08151	GLI1	Q13627	DYRK1A	S1071	S1070N	1070	Missense	proximal	-1	no	34.247	35.106	EPSD	TCGA	34.163	Up-regulation
CMGC_DYRK_DYRK1_DYRK1A_ST	P08151	GLI1	Q13627	DYRK1A	T1074	P1077L	1077	Missense	distal	3	no	40.805	40.812	EPSD	TCGA;COSMIC	34.163	Up-regulation
CMGC_DYRK_DYRK1_DYRK1A_ST	P08151	GLI1	Q13627	DYRK1A	T1074	G1069S	1069	Missense	distal	-5	no	40.805	40.430	EPSD	TCGA;COSMIC	34.163	Down-regulation
CMGC_DYRK_DYRK1_DYRK1A_ST	P08151	GLI1	Q13627	DYRK1A	T1074	S1070N	1070	Missense	distal	-4	no	40.805	40.809	EPSD	TCGA	34.163	Up-regulation
CMGC_DYRK_DYRK1_DYRK1A_ST	Q13627	DYRK1A	Q13627	DYRK1A	S14	R16W	16	Missense	proximal	2	no	40.592	39.486	EPSD	TCGA;ICGC;COSMIC	34.163	Down-regulation
CMGC_DYRK_DYRK1_DYRK1A_ST	Q13627	DYRK1A	Q13627	DYRK1A	S496	S494C	494	Missense	proximal	-2	no	39.455	30.061	EPSD	TCGA;COSMIC	34.163	Loss
CMGC_DYRK_DYRK1_DYRK1A_ST	Q13627	DYRK1A	Q13627	DYRK1A	S496	T495A	495	Missense	proximal	-1	no	39.455	40.157	EPSD	TCGA;ICGC;COSMIC	34.163	Up-regulation
CMGC_DYRK_DYRK1_DYRK1A_ST	Q13627	DYRK1A	Q13627	DYRK1A	S496	E500V	500	Missense	distal	4	no	39.455	40.807	EPSD	TCGA;COSMIC	34.163	Up-regulation
CMGC_DYRK_DYRK1_DYRK1A_ST	Q13627	DYRK1A	Q13627	DYRK1A	S496	V493I	493	Missense	distal	-3	no	39.455	37.565	EPSD	TCGA;ICGC;COSMIC	34.163	Down-regulation
CMGC_DYRK_DYRK1_DYRK1A_ST	Q13627	DYRK1A	Q13627	DYRK1A	S505	G506V	506	Missense	proximal	1	no	31.075	35.905	EPSD	TCGA;COSMIC	34.163	Gain
CMGC_DYRK_DYRK1_DYRK1A_ST	Q13627	DYRK1A	Q13627	DYRK1A	S515	S519L	519	Missense	distal	4	no	32.768	34.618	EPSD	TCGA;ICGC;COSMIC;CCLE	34.163	Gain
CMGC_DYRK_DYRK1_DYRK1A_ST	Q13627	DYRK1A	Q13627	DYRK1A	S529	P531S	531	Missense	proximal	2	no	52.145	52.045	PhosphoSitePlus	TCGA;COSMIC	34.163	Down-regulation
CMGC_DYRK_DYRK1_DYRK1A_ST	Q13627	DYRK1A	Q13627	DYRK1A	S529	D530H	530	Missense	proximal	1	no	52.145	27.990	PhosphoSitePlus	TCGA;COSMIC	34.163	Loss
CMGC_DYRK_DYRK1_DYRK1A_ST	Q13627	DYRK1A	Q13627	DYRK1A	S529	R528W	528	Missense	proximal	-1	no	52.145	53.302	PhosphoSitePlus	TCGA;ICGC;COSMIC	34.163	Up-regulation
CMGC_DYRK_DYRK1_DYRK1A_ST	Q13627	DYRK1A	Q13627	DYRK1A	T751	D744H	744	Missense	distal	-7	no	40.532	39.933	EPSD	TCGA;ICGC;COSMIC	34.163	Down-regulation
CMGC_DYRK_DYRK1_DYRK1A_ST	Q13627	DYRK1A	Q13627	DYRK1A	T751	E746Q	746	Missense	distal	-5	no	40.532	41.118	EPSD	TCGA;ICGC;COSMIC	34.163	Up-regulation
CMGC_DYRK_DYRK1_DYRK1A_ST	Q13627	DYRK1A	Q13627	DYRK1A	S758	P759L	759	Missense	proximal	1	no	37.400	-4.931	EPSD	TCGA;ICGC	34.163	Loss
CMGC_DYRK_DYRK1_DYRK1A_ST	Q13627	DYRK1A	Q13627	DYRK1A	S758	V760I	760	Missense	proximal	2	no	37.400	37.130	EPSD	TCGA;ICGC;COSMIC	34.163	Down-regulation
CMGC_DYRK_DYRK1_DYRK1A_ST	O75533	SF3B1	Q13627	DYRK1A	T142	M147V	147	Missense	distal	5	no	33.356	34.926	EPSD	TCGA;ICGC;COSMIC	34.163	Gain
CMGC_DYRK_DYRK1_DYRK1A_ST	O75533	SF3B1	Q13627	DYRK1A	T207	Q206E	206	Missense	proximal	-1	no	45.861	45.748	EPSD	TCGA;ICGC;COSMIC	34.163	Down-regulation
CMGC_DYRK_DYRK1_DYRK1A_ST	O75533	SF3B1	Q13627	DYRK1A	T207	Q206R	206	Missense	proximal	-1	no	45.861	45.331	EPSD	TCGA;ICGC;COSMIC	34.163	Down-regulation
CMGC_DYRK_DYRK1_DYRK1A_ST	O75533	SF3B1	Q13627	DYRK1A	T211	Q206E	206	Missense	distal	-5	no	36.767	36.181	EPSD	TCGA;ICGC;COSMIC	34.163	Down-regulation
CMGC_DYRK_DYRK1_DYRK1A_ST	O75533	SF3B1	Q13627	DYRK1A	T211	Q206R	206	Missense	distal	-5	no	36.767	37.918	EPSD	TCGA;ICGC;COSMIC	34.163	Up-regulation
CMGC_DYRK_DYRK1_DYRK1A_ST	O75533	SF3B1	Q13627	DYRK1A	T223	P228S	228	Missense	distal	5	no	41.387	41.448	EPSD	TCGA;ICGC;COSMIC	34.163	Up-regulation
CMGC_DYRK_DYRK1_DYRK1A_ST	O75533	SF3B1	Q13627	DYRK1A	T223	S229F	229	Missense	distal	6	no	41.387	41.464	EPSD	TCGA;ICGC;COSMIC	34.163	Up-regulation
CMGC_DYRK_DYRK1_DYRK1A_ST	O75533	SF3B1	Q13627	DYRK1A	T223	Q220K	220	Missense	distal	-3	no	41.387	47.293	EPSD	TCGA;ICGC;COSMIC	34.163	Up-regulation
CMGC_DYRK_DYRK1_DYRK1A_ST	O75533	SF3B1	Q13627	DYRK1A	T227	R231I	231	Missense	distal	4	no	30.834	34.857	EPSD	TCGA;ICGC;COSMIC	34.163	Gain
CMGC_DYRK_DYRK1_DYRK1A_ST	O75533	SF3B1	Q13627	DYRK1A	T261	D255N	255	Missense	distal	-6	no	45.422	45.076	EPSD	TCGA;ICGC;COSMIC	34.163	Down-regulation
CMGC_DYRK_DYRK1_DYRK1A_ST	O75533	SF3B1	Q13627	DYRK1A	T261	P258L	258	Missense	distal	-3	no	45.422	43.429	EPSD	TCGA	34.163	Down-regulation
CMGC_DYRK_DYRK1_DYRK1A_ST	O75533	SF3B1	Q13627	DYRK1A	T261	T267N	267	Missense	distal	6	no	45.422	45.434	EPSD	TCGA;ICGC;COSMIC	34.163	Up-regulation
CMGC_DYRK_DYRK1_DYRK1A_ST	O75533	SF3B1	Q13627	DYRK1A	T267	T267N	267	Missense	central	0	yes	47.765	0.000	EPSD	TCGA;ICGC;COSMIC	34.163	Loss
CMGC_DYRK_DYRK1_DYRK1A_ST	O75533	SF3B1	Q13627	DYRK1A	T267	P274L	274	Missense	distal	7	no	47.765	49.424	EPSD	TCGA;ICGC;COSMIC	34.163	Up-regulation
CMGC_DYRK_DYRK1_DYRK1A_ST	O75533	SF3B1	Q13627	DYRK1A	T273	T267N	267	Missense	distal	-6	no	54.664	53.906	PhosphoSitePlus;EPSD	TCGA;ICGC;COSMIC	34.163	Down-regulation
CMGC_DYRK_DYRK1_DYRK1A_ST	O75533	SF3B1	Q13627	DYRK1A	T273	A277S	277	Missense	distal	4	no	54.664	54.204	PhosphoSitePlus;EPSD	TCGA;ICGC;COSMIC	34.163	Down-regulation
CMGC_DYRK_DYRK1_DYRK1A_ST	O75533	SF3B1	Q13627	DYRK1A	T273	P274L	274	Missense	proximal	1	no	54.664	12.333	PhosphoSitePlus;EPSD	TCGA;ICGC;COSMIC	34.163	Loss
CMGC_DYRK_DYRK1_DYRK1A_ST	O75533	SF3B1	Q13627	DYRK1A	T278	A277S	277	Missense	proximal	-1	no	35.001	34.769	EPSD	TCGA;ICGC;COSMIC	34.163	Down-regulation
CMGC_DYRK_DYRK1_DYRK1A_ST	O75533	SF3B1	Q13627	DYRK1A	T278	P274L	274	Missense	distal	-4	no	35.001	34.999	EPSD	TCGA;ICGC;COSMIC	34.163	Down-regulation
CMGC_DYRK_DYRK1_DYRK1A_ST	O75533	SF3B1	Q13627	DYRK1A	T296	R292K	292	Missense	distal	-4	no	39.539	39.503	EPSD	TCGA;ICGC;COSMIC	34.163	Down-regulation
CMGC_DYRK_DYRK1_DYRK1A_ST	O75533	SF3B1	Q13627	DYRK1A	T303	S308R	308	Missense	distal	5	no	45.884	47.458	EPSD	TCGA;ICGC;COSMIC	34.163	Up-regulation
CMGC_DYRK_DYRK1_DYRK1A_ST	O75533	SF3B1	Q13627	DYRK1A	T313	S308R	308	Missense	distal	-5	no	37.729	38.959	EPSD	TCGA;ICGC;COSMIC	34.163	Up-regulation
CMGC_DYRK_DYRK1_DYRK1A_ST	O75533	SF3B1	Q13627	DYRK1A	T313	T316A	316	Missense	distal	3	no	37.729	38.160	EPSD	TCGA;ICGC	34.163	Up-regulation
CMGC_DYRK_DYRK1_DYRK1A_ST	O75533	SF3B1	Q13627	DYRK1A	T313	R315Q	315	Missense	proximal	2	no	37.729	37.539	EPSD	TCGA;ICGC;COSMIC;GDSC;CCLE	34.163	Down-regulation
CMGC_DYRK_DYRK1_DYRK1A_ST	O75533	SF3B1	Q13627	DYRK1A	S322	T316A	316	Missense	distal	-6	no	35.765	36.103	EPSD	TCGA;ICGC	34.163	Up-regulation
CMGC_DYRK_DYRK1_DYRK1A_ST	O75533	SF3B1	Q13627	DYRK1A	S322	D321V	321	Missense	proximal	-1	no	35.765	35.551	EPSD	TCGA;ICGC;COSMIC	34.163	Down-regulation
CMGC_DYRK_DYRK1_DYRK1A_ST	O75533	SF3B1	Q13627	DYRK1A	S322	I323V	323	Missense	proximal	1	no	35.765	36.165	EPSD	TCGA;ICGC;COSMIC	34.163	Up-regulation
CMGC_DYRK_DYRK1_DYRK1A_ST	O75533	SF3B1	Q13627	DYRK1A	S322	R315Q	315	Missense	distal	-7	no	35.765	36.267	EPSD	TCGA;ICGC;COSMIC;GDSC;CCLE	34.163	Up-regulation
CMGC_DYRK_DYRK1_DYRK1A_ST	O75533	SF3B1	Q13627	DYRK1A	S322	P327R	327	Missense	distal	5	no	35.765	37.400	EPSD	TCGA;ICGC;COSMIC	34.163	Up-regulation
CMGC_DYRK_DYRK1_DYRK1A_ST	O75533	SF3B1	Q13627	DYRK1A	T326	D321V	321	Missense	distal	-5	no	45.726	46.316	EPSD	TCGA;ICGC;COSMIC	34.163	Up-regulation
CMGC_DYRK_DYRK1_DYRK1A_ST	O75533	SF3B1	Q13627	DYRK1A	T326	I323V	323	Missense	distal	-3	no	45.726	47.616	EPSD	TCGA;ICGC;COSMIC	34.163	Up-regulation
CMGC_DYRK_DYRK1_DYRK1A_ST	O75533	SF3B1	Q13627	DYRK1A	T326	P327R	327	Missense	proximal	1	no	45.726	30.645	EPSD	TCGA;ICGC;COSMIC	34.163	Loss
CMGC_DYRK_DYRK1_DYRK1A_ST	O75533	SF3B1	Q13627	DYRK1A	S344	P351L	351	Missense	distal	7	no	40.717	42.376	EPSD	TCGA;ICGC;COSMIC	34.163	Up-regulation
CMGC_DYRK_DYRK1_DYRK1A_ST	O75533	SF3B1	Q13627	DYRK1A	S344	P351S	351	Missense	distal	7	no	40.717	40.222	EPSD	TCGA;ICGC;COSMIC	34.163	Down-regulation
CMGC_DYRK_DYRK1_DYRK1A_ST	O75533	SF3B1	Q13627	DYRK1A	T350	P351L	351	Missense	proximal	1	no	42.910	0.579	EPSD	TCGA;ICGC;COSMIC	34.163	Loss
CMGC_DYRK_DYRK1_DYRK1A_ST	O75533	SF3B1	Q13627	DYRK1A	T350	P351S	351	Missense	proximal	1	no	42.910	20.957	EPSD	TCGA;ICGC;COSMIC	34.163	Loss
CMGC_DYRK_DYRK1_DYRK1A_ST	O75533	SF3B1	Q13627	DYRK1A	T354	P351L	351	Missense	distal	-3	no	42.439	40.446	EPSD	TCGA;ICGC;COSMIC	34.163	Down-regulation
CMGC_DYRK_DYRK1_DYRK1A_ST	O75533	SF3B1	Q13627	DYRK1A	T354	P351S	351	Missense	distal	-3	no	42.439	45.211	EPSD	TCGA;ICGC;COSMIC	34.163	Up-regulation
CMGC_DYRK_DYRK1_DYRK1A_ST	O75533	SF3B1	Q13627	DYRK1A	T358	P351L	351	Missense	distal	-7	no	39.400	40.402	EPSD	TCGA;ICGC;COSMIC	34.163	Up-regulation
CMGC_DYRK_DYRK1_DYRK1A_ST	O75533	SF3B1	Q13627	DYRK1A	T358	P351S	351	Missense	distal	-7	no	39.400	39.337	EPSD	TCGA;ICGC;COSMIC	34.163	Down-regulation
CMGC_DYRK_DYRK1_DYRK1A_ST	O75533	SF3B1	Q13627	DYRK1A	S400	R397C	397	Missense	distal	-3	no	54.946	31.441	EPSD	TCGA;ICGC;COSMIC	34.163	Loss
CMGC_DYRK_DYRK1_DYRK1A_ST	O75533	SF3B1	Q13627	DYRK1A	T434	A433G	433	Missense	proximal	-1	no	53.430	53.769	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	34.163	Up-regulation
CMGC_DYRK_DYRK1_DYRK1A_ST	O75533	SF3B1	Q13627	DYRK1A	T436	A433G	433	Missense	distal	-3	no	32.586	37.809	EPSD	TCGA;ICGC;COSMIC	34.163	Gain
CMGC_DYRK_DYRK1_DYRK1A_ST	O75533	SF3B1	Q13627	DYRK1A	S488	E490K	490	Missense	proximal	2	no	39.998	40.306	EPSD	TCGA;ICGC;COSMIC	34.163	Up-regulation
CMGC_DYRK_DYRK1_DYRK1A_ST	O75533	SF3B1	Q13627	DYRK1A	S541	S541P	541	Missense	central	0	yes	36.901	0.000	EPSD	TCGA;ICGC;COSMIC	34.163	Loss
CMGC_DYRK_DYRK1_DYRK1A_ST	O75533	SF3B1	Q13627	DYRK1A	S541	L544P	544	Missense	distal	3	no	36.901	36.895	EPSD	TCGA;ICGC;COSMIC	34.163	Down-regulation
CMGC_DYRK_DYRK1_DYRK1A_ST	O75533	SF3B1	Q13627	DYRK1A	T1021	N1026S	1026	Missense	distal	5	no	39.564	42.498	EPSD	TCGA;ICGC;COSMIC	34.163	Up-regulation
CMGC_DYRK_DYRK1_DYRK1A_ST	O75533	SF3B1	Q13627	DYRK1A	T1021	R1019G	1019	Missense	proximal	-2	no	39.564	32.869	EPSD	TCGA;ICGC;COSMIC	34.163	Loss
CMGC_DYRK_DYRK1_DYRK1A_ST	O75533	SF3B1	Q13627	DYRK1A	T1021	D1015G	1015	Missense	distal	-6	no	39.564	39.955	EPSD	TCGA;ICGC;COSMIC	34.163	Up-regulation
CMGC_DYRK_DYRK1_DYRK1A_ST	O75533	SF3B1	Q13627	DYRK1A	T1080	I1073M	1073	Missense	distal	-7	no	34.821	34.638	EPSD	TCGA;ICGC;COSMIC	34.163	Down-regulation
CMGC_DYRK_DYRK1_DYRK1A_ST	O75533	SF3B1	Q13627	DYRK1A	T1080	R1075K	1075	Missense	distal	-5	no	34.821	33.656	EPSD	TCGA;ICGC;COSMIC	34.163	Loss
CMGC_DYRK_DYRK1_DYRK1A_ST	O75533	SF3B1	Q13627	DYRK1A	T1080	A1076V	1076	Missense	distal	-4	no	34.821	34.781	EPSD	TCGA;ICGC;COSMIC	34.163	Down-regulation
CMGC_DYRK_DYRK1_DYRK1A_ST	O75533	SF3B1	Q13627	DYRK1A	S1271	I1268M	1268	Missense	distal	-3	no	43.021	38.992	EPSD	TCGA;COSMIC	34.163	Down-regulation
CMGC_DYRK_DYRK1_DYRK1A_ST	O75533	SF3B1	Q13627	DYRK1A	S1271	I1274F	1274	Missense	distal	3	no	43.021	42.921	EPSD	TCGA;ICGC;COSMIC	34.163	Down-regulation
CMGC_DYRK_DYRK1_DYRK1A_ST	Q96S94	CCNL2	Q13627	DYRK1A	S25	S32L	32	Missense	distal	7	no	41.427	43.582	EPSD	TCGA	34.163	Up-regulation
CMGC_DYRK_DYRK1_DYRK1A_ST	Q96S94	CCNL2	Q13627	DYRK1A	S32	S32L	32	Missense	central	0	yes	43.486	0.000	EPSD	TCGA	34.163	Loss
CMGC_DYRK_DYRK1_DYRK1A_ST	Q96S94	CCNL2	Q13627	DYRK1A	S32	V35L	35	Missense	distal	3	no	43.486	43.564	EPSD	TCGA;ICGC;COSMIC	34.163	Up-regulation
CMGC_DYRK_DYRK1_DYRK1A_ST	Q96S94	CCNL2	Q13627	DYRK1A	S330	P331A	331	Missense	proximal	1	no	53.095	22.950	EPSD;PhosphoSitePlus	TCGA;COSMIC	34.163	Loss
CMGC_DYRK_DYRK1_DYRK1A_ST	Q96S94	CCNL2	Q13627	DYRK1A	S330	S327L	327	Missense	distal	-3	no	53.095	48.330	EPSD;PhosphoSitePlus	TCGA;COSMIC	34.163	Down-regulation
CMGC_DYRK_DYRK1_DYRK1A_ST	Q96S94	CCNL2	Q13627	DYRK1A	S330	L335M	335	Missense	distal	5	no	53.095	48.819	EPSD;PhosphoSitePlus	TCGA;COSMIC	34.163	Down-regulation
CMGC_DYRK_DYRK1_DYRK1A_ST	Q96S94	CCNL2	Q13627	DYRK1A	S338	K340E	340	Missense	proximal	2	no	53.574	53.265	PhosphoSitePlus;EPSD	TCGA	34.163	Down-regulation
CMGC_DYRK_DYRK1_DYRK1A_ST	Q96S94	CCNL2	Q13627	DYRK1A	S338	P331A	331	Missense	distal	-7	no	53.574	53.889	PhosphoSitePlus;EPSD	TCGA;COSMIC	34.163	Up-regulation
CMGC_DYRK_DYRK1_DYRK1A_ST	Q96S94	CCNL2	Q13627	DYRK1A	S338	L335M	335	Missense	distal	-3	no	53.574	51.739	PhosphoSitePlus;EPSD	TCGA;COSMIC	34.163	Down-regulation
CMGC_DYRK_DYRK1_DYRK1A_ST	Q96S94	CCNL2	Q13627	DYRK1A	S345	K340E	340	Missense	distal	-5	no	41.351	40.778	EPSD	TCGA	34.163	Down-regulation
CMGC_DYRK_DYRK1_DYRK1A_ST	Q96S94	CCNL2	Q13627	DYRK1A	S345	L350M	350	Missense	distal	5	no	41.351	37.076	EPSD	TCGA	34.163	Down-regulation
CMGC_DYRK_DYRK1_DYRK1A_ST	Q96S94	CCNL2	Q13627	DYRK1A	S351	L350M	350	Missense	proximal	-1	no	37.489	38.662	EPSD	TCGA	34.163	Up-regulation
CMGC_DYRK_DYRK1_DYRK1A_ST	Q96S94	CCNL2	Q13627	DYRK1A	T355	L350M	350	Missense	distal	-5	no	36.870	36.953	EPSD	TCGA	34.163	Up-regulation
CMGC_DYRK_DYRK1_DYRK1A_ST	Q96S94	CCNL2	Q13627	DYRK1A	S369	N372S	372	Missense	distal	3	no	54.235	54.645	EPSD;PhosphoSitePlus	TCGA;COSMIC	34.163	Up-regulation
CMGC_DYRK_DYRK1_DYRK1A_ST	Q96S94	CCNL2	Q13627	DYRK1A	S369	A367V	367	Missense	proximal	-2	no	54.235	52.327	EPSD;PhosphoSitePlus	TCGA;ICGC	34.163	Down-regulation
CMGC_DYRK_DYRK1_DYRK1A_ST	Q96S94	CCNL2	Q13627	DYRK1A	S394	R387C	387	Missense	distal	-7	no	38.187	39.112	EPSD	TCGA;ICGC;COSMIC	34.163	Up-regulation
CMGC_DYRK_DYRK1_DYRK1A_ST	Q96S94	CCNL2	Q13627	DYRK1A	S406	G413S	413	Missense	distal	7	no	38.426	37.895	EPSD	TCGA;COSMIC	34.163	Down-regulation
CMGC_DYRK_DYRK1_DYRK1A_ST	Q96S94	CCNL2	Q13627	DYRK1A	S415	G413S	413	Missense	proximal	-2	no	32.833	35.801	EPSD	TCGA;COSMIC	34.163	Gain
CMGC_DYRK_DYRK1_DYRK1A_ST	Q96S94	CCNL2	Q13627	DYRK1A	S417	G413S	413	Missense	distal	-4	no	37.137	37.159	EPSD	TCGA;COSMIC	34.163	Up-regulation
CMGC_DYRK_DYRK1_DYRK1A_ST	Q96S94	CCNL2	Q13627	DYRK1A	S423	P429L	429	Missense	distal	6	no	35.042	35.114	EPSD	TCGA	34.163	Up-regulation
CMGC_DYRK_DYRK1_DYRK1A_ST	Q96S94	CCNL2	Q13627	DYRK1A	S427	P429L	429	Missense	proximal	2	no	57.911	57.410	EPSD	TCGA	34.163	Down-regulation
CMGC_DYRK_DYRK1_DYRK1A_ST	Q96S94	CCNL2	Q13627	DYRK1A	S467	S467F	467	Missense	central	0	yes	36.486	0.000	EPSD	TCGA;ICGC;COSMIC	34.163	Loss
CMGC_DYRK_DYRK1_DYRK1A_ST	Q96S94	CCNL2	Q13627	DYRK1A	S467	R464W	464	Missense	distal	-3	no	36.486	11.670	EPSD	TCGA;ICGC;COSMIC	34.163	Loss
CMGC_DYRK_DYRK1_DYRK1A_ST	Q96S94	CCNL2	Q13627	DYRK1A	S467	S463N	463	Missense	distal	-4	no	36.486	36.490	EPSD	TCGA;COSMIC	34.163	Up-regulation
CMGC_DYRK_DYRK1_DYRK1A_ST	Q96S94	CCNL2	Q13627	DYRK1A	S471	R464W	464	Missense	distal	-7	no	33.762	34.676	EPSD	TCGA;ICGC;COSMIC	34.163	Gain
CMGC_DYRK_DYRK1_DYRK1A_ST	Q96S94	CCNL2	Q13627	DYRK1A	S473	S467F	467	Missense	distal	-6	no	44.312	42.802	EPSD	TCGA;ICGC;COSMIC	34.163	Down-regulation
CMGC_DYRK_DYRK1_DYRK1A_ST	Q96S94	CCNL2	Q13627	DYRK1A	S473	A477V	477	Missense	distal	4	no	44.312	46.288	EPSD	TCGA;ICGC	34.163	Up-regulation
CMGC_DYRK_DYRK1_DYRK1A_ST	Q52LA3	LIN52	Q13627	DYRK1A	S28	D25H	25	Missense	distal	-3	no	53.810	53.834	PhosphoSitePlus	TCGA;ICGC;COSMIC	34.163	Up-regulation
CMGC_DYRK_DYRK1_DYRK1A_ST	O43597	SPRY2	Q13627	DYRK1A	S97	L94R	94	Missense	distal	-3	no	22.103	35.458	EPSD	TCGA;ICGC;COSMIC	34.163	Gain
CMGC_DYRK_DYRK1_DYRK1A_ST	O43597	SPRY2	Q13627	DYRK1A	S110	A105V	105	Missense	distal	-5	no	34.027	34.459	EPSD	TCGA;ICGC;COSMIC	34.163	Gain
CMGC_DYRK_DYRK1_DYRK1A_ST	O43597	SPRY2	Q13627	DYRK1A	S139	G137R	137	Missense	proximal	-2	no	30.442	37.137	EPSD	TCGA;ICGC;COSMIC	34.163	Gain
CMGC_DYRK_DYRK1_DYRK1A_ST	O43597	SPRY2	Q13627	DYRK1A	S142	G137R	137	Missense	distal	-5	no	33.573	34.428	EPSD	TCGA;ICGC;COSMIC	34.163	Gain
CMGC_DYRK_DYRK1_DYRK1A_ST	O43597	SPRY2	Q13627	DYRK1A	S142	A146V	146	Missense	distal	4	no	33.573	35.549	EPSD	TCGA;ICGC;COSMIC	34.163	Gain
CMGC_DYRK_DYRK1_DYRK1A_ST	P04637	TP53	Q13627	DYRK1A	S33	P27S	27	Missense	distal	-6	no	34.790	35.493	EPSD	TCGA;ICGC;COSMIC	34.163	Up-regulation
CMGC_DYRK_DYRK1_DYRK1A_ST	P04637	TP53	Q13627	DYRK1A	S33	P27L	27	Missense	distal	-6	no	34.790	34.847	EPSD	TCGA;ICGC;COSMIC;GDSC;CCLE	34.163	Up-regulation
CMGC_DYRK_DYRK1_DYRK1A_ST	P04637	TP53	Q13627	DYRK1A	T81	A79V	79	Missense	proximal	-2	no	42.596	40.688	EPSD	TCGA;ICGC;COSMIC	34.163	Down-regulation
CMGC_DYRK_DYRK1_DYRK1A_ST	P04637	TP53	Q13627	DYRK1A	T81	P77L	77	Missense	distal	-4	no	42.596	42.594	EPSD	TCGA;ICGC;COSMIC	34.163	Down-regulation
CMGC_DYRK_DYRK1_DYRK1A_ST	P04637	TP53	Q13627	DYRK1A	T81	P82L	82	Missense	proximal	1	no	42.596	0.265	EPSD	TCGA;ICGC;COSMIC	34.163	Loss
CMGC_DYRK_DYRK1_DYRK1A_ST	P04637	TP53	Q13627	DYRK1A	T81	A74T	74	Missense	distal	-7	no	42.596	41.997	EPSD	TCGA;ICGC;COSMIC	34.163	Down-regulation
CMGC_DYRK_DYRK1_DYRK1A_ST	P04637	TP53	Q13627	DYRK1A	S99	G105C	105	Missense	distal	6	no	36.467	36.617	EPSD	TCGA;ICGC;COSMIC;GDSC	34.163	Up-regulation
CMGC_DYRK_DYRK1_DYRK1A_ST	P04637	TP53	Q13627	DYRK1A	S99	S106R	106	Missense	distal	7	no	36.467	35.487	EPSD	TCGA;ICGC;COSMIC;GDSC;CCLE	34.163	Down-regulation
CMGC_DYRK_DYRK1_DYRK1A_ST	P04637	TP53	Q13627	DYRK1A	S99	G105R	105	Missense	distal	6	no	36.467	36.472	EPSD	TCGA;ICGC;COSMIC;CCLE	34.163	Up-regulation
CMGC_DYRK_DYRK1_DYRK1A_ST	P04637	TP53	Q13627	DYRK1A	S99	G105V	105	Missense	distal	6	no	36.467	36.639	EPSD	TCGA;ICGC;COSMIC	34.163	Up-regulation
CMGC_DYRK_DYRK1_DYRK1A_ST	P04637	TP53	Q13627	DYRK1A	S99	G105D	105	Missense	distal	6	no	36.467	36.614	EPSD	TCGA;ICGC;COSMIC	34.163	Up-regulation
CMGC_DYRK_DYRK1_DYRK1A_ST	P04637	TP53	Q13627	DYRK1A	S99	G105S	105	Missense	distal	6	no	36.467	36.533	EPSD	TCGA;ICGC;COSMIC	34.163	Up-regulation
CMGC_DYRK_DYRK1_DYRK1A_ST	P04637	TP53	Q13627	DYRK1A	S99	V97D	97	Missense	proximal	-2	no	36.467	34.111	EPSD	TCGA;ICGC;COSMIC	34.163	Loss
CMGC_DYRK_DYRK1_DYRK1A_ST	P04637	TP53	Q13627	DYRK1A	S99	P92S	92	Missense	distal	-7	no	36.467	36.404	EPSD	TCGA;ICGC	34.163	Down-regulation
CMGC_DYRK_DYRK1_DYRK1A_ST	P04637	TP53	Q13627	DYRK1A	S127	K132N	132	Missense	distal	5	no	37.482	33.018	EPSD	TCGA;ICGC;COSMIC;GDSC;CCLE	34.163	Loss
CMGC_DYRK_DYRK1_DYRK1A_ST	P04637	TP53	Q13627	DYRK1A	S127	S121Y	121	Missense	distal	-6	no	37.482	36.576	EPSD	TCGA;ICGC;COSMIC	34.163	Down-regulation
CMGC_DYRK_DYRK1_DYRK1A_ST	P04637	TP53	Q13627	DYRK1A	S127	M133K	133	Missense	distal	6	no	37.482	37.338	EPSD	TCGA;ICGC;COSMIC;CCLE	34.163	Down-regulation
CMGC_DYRK_DYRK1_DYRK1A_ST	P04637	TP53	Q13627	DYRK1A	S127	K132E	132	Missense	distal	5	no	37.482	37.468	EPSD	TCGA;ICGC;COSMIC;GDSC;CCLE	34.163	Down-regulation
CMGC_DYRK_DYRK1_DYRK1A_ST	P04637	TP53	Q13627	DYRK1A	S127	Y126C	126	Missense	proximal	-1	no	37.482	37.157	EPSD	TCGA;ICGC;COSMIC;GDSC	34.163	Down-regulation
CMGC_DYRK_DYRK1_DYRK1A_ST	P04637	TP53	Q13627	DYRK1A	S127	S127P	127	Missense	central	0	yes	37.482	0.000	EPSD	TCGA;ICGC;COSMIC;GDSC;CCLE	34.163	Loss
CMGC_DYRK_DYRK1_DYRK1A_ST	P04637	TP53	Q13627	DYRK1A	S127	Y126N	126	Missense	proximal	-1	no	37.482	36.576	EPSD	TCGA;ICGC;COSMIC	34.163	Down-regulation
CMGC_DYRK_DYRK1_DYRK1A_ST	P04637	TP53	Q13627	DYRK1A	S127	L130V	130	Missense	distal	3	no	37.482	37.404	EPSD	TCGA;ICGC;COSMIC;GDSC;CCLE	34.163	Down-regulation
CMGC_DYRK_DYRK1_DYRK1A_ST	P04637	TP53	Q13627	DYRK1A	S127	K132T	132	Missense	distal	5	no	37.482	37.436	EPSD	TCGA;ICGC;COSMIC;GDSC;CCLE	34.163	Down-regulation
CMGC_DYRK_DYRK1_DYRK1A_ST	P04637	TP53	Q13627	DYRK1A	S127	S127Y	127	Missense	central	0	yes	37.482	0.000	EPSD	TCGA;ICGC;COSMIC	34.163	Loss
CMGC_DYRK_DYRK1_DYRK1A_ST	P04637	TP53	Q13627	DYRK1A	S127	S127F	127	Missense	central	0	yes	37.482	0.000	EPSD	TCGA;ICGC;COSMIC;CCLE	34.163	Loss
CMGC_DYRK_DYRK1_DYRK1A_ST	P04637	TP53	Q13627	DYRK1A	S127	M133R	133	Missense	distal	6	no	37.482	37.267	EPSD	TCGA;ICGC;COSMIC	34.163	Down-regulation
CMGC_DYRK_DYRK1_DYRK1A_ST	P04637	TP53	Q13627	DYRK1A	S127	K132R	132	Missense	distal	5	no	37.482	37.526	EPSD	TCGA;ICGC;COSMIC;GDSC;CCLE	34.163	Up-regulation
CMGC_DYRK_DYRK1_DYRK1A_ST	P04637	TP53	Q13627	DYRK1A	S127	F134L	134	Missense	distal	7	no	37.482	36.240	EPSD	TCGA;ICGC;COSMIC;CCLE	34.163	Down-regulation
CMGC_DYRK_DYRK1_DYRK1A_ST	P04637	TP53	Q13627	DYRK1A	S127	Y126S	126	Missense	proximal	-1	no	37.482	35.717	EPSD	TCGA;ICGC;COSMIC	34.163	Down-regulation
CMGC_DYRK_DYRK1_DYRK1A_ST	P04637	TP53	Q13627	DYRK1A	S127	L130P	130	Missense	distal	3	no	37.482	37.475	EPSD	TCGA;ICGC;COSMIC	34.163	Down-regulation
CMGC_DYRK_DYRK1_DYRK1A_ST	P04637	TP53	Q13627	DYRK1A	S127	L130F	130	Missense	distal	3	no	37.482	37.440	EPSD	TCGA;ICGC;COSMIC;CCLE	34.163	Down-regulation
CMGC_DYRK_DYRK1_DYRK1A_ST	P04637	TP53	Q13627	DYRK1A	S127	F134V	134	Missense	distal	7	no	37.482	36.426	EPSD	TCGA;ICGC;COSMIC	34.163	Down-regulation
CMGC_DYRK_DYRK1_DYRK1A_ST	P04637	TP53	Q13627	DYRK1A	S127	T125M	125	Missense	proximal	-2	no	37.482	21.332	EPSD	TCGA;ICGC;COSMIC;GDSC	34.163	Loss
CMGC_DYRK_DYRK1_DYRK1A_ST	P04637	TP53	Q13627	DYRK1A	S127	Y126D	126	Missense	proximal	-1	no	37.482	36.708	EPSD	TCGA;ICGC;COSMIC;GDSC	34.163	Down-regulation
CMGC_DYRK_DYRK1_DYRK1A_ST	P04637	TP53	Q13627	DYRK1A	S127	K120E	120	Missense	distal	-7	no	37.482	37.242	EPSD	TCGA;ICGC;COSMIC	34.163	Down-regulation
CMGC_DYRK_DYRK1_DYRK1A_ST	P04637	TP53	Q13627	DYRK1A	S127	N131S	131	Missense	distal	4	no	37.482	36.476	EPSD	TCGA;ICGC;COSMIC	34.163	Down-regulation
CMGC_DYRK_DYRK1_DYRK1A_ST	P04637	TP53	Q13627	DYRK1A	S127	T125P	125	Missense	proximal	-2	no	37.482	42.719	EPSD	TCGA;ICGC;COSMIC;CCLE	34.163	Up-regulation
CMGC_DYRK_DYRK1_DYRK1A_ST	P04637	TP53	Q13627	DYRK1A	S127	S127C	127	Missense	central	0	yes	37.482	0.000	EPSD	TCGA;ICGC;COSMIC;CCLE	34.163	Loss
CMGC_DYRK_DYRK1_DYRK1A_ST	P04637	TP53	Q13627	DYRK1A	S127	N131I	131	Missense	distal	4	no	37.482	39.348	EPSD	TCGA;ICGC;COSMIC	34.163	Up-regulation
CMGC_DYRK_DYRK1_DYRK1A_ST	P04637	TP53	Q13627	DYRK1A	S127	Y126H	126	Missense	proximal	-1	no	37.482	36.021	EPSD	TCGA;ICGC;COSMIC;GDSC	34.163	Down-regulation
CMGC_DYRK_DYRK1_DYRK1A_ST	P04637	TP53	Q13627	DYRK1A	S127	K132Q	132	Missense	distal	5	no	37.482	38.517	EPSD	TCGA;ICGC;COSMIC;GDSC;CCLE	34.163	Up-regulation
CMGC_DYRK_DYRK1_DYRK1A_ST	P04637	TP53	Q13627	DYRK1A	S127	L130R	130	Missense	distal	3	no	37.482	37.718	EPSD	TCGA;ICGC;COSMIC;CCLE	34.163	Up-regulation
CMGC_DYRK_DYRK1_DYRK1A_ST	P04637	TP53	Q13627	DYRK1A	S183	E180K	180	Missense	distal	-3	no	27.070	37.563	EPSD	TCGA;ICGC;COSMIC;CCLE	34.163	Gain
CMGC_DYRK_DYRK1_DYRK1A_ST	P04637	TP53	Q13627	DYRK1A	T304	A307V	307	Missense	distal	3	no	36.536	36.134	EPSD	TCGA;ICGC;COSMIC;GDSC	34.163	Down-regulation
CMGC_DYRK_DYRK1_DYRK1A_ST	P04637	TP53	Q13627	DYRK1A	S315	K319N	319	Missense	distal	4	no	40.613	40.893	EPSD	TCGA;ICGC;COSMIC	34.163	Up-regulation
CMGC_DYRK_DYRK1_DYRK1A_ST	P04637	TP53	Q13627	DYRK1A	S315	K320E	320	Missense	distal	5	no	40.613	40.599	EPSD	TCGA;ICGC;COSMIC	34.163	Down-regulation
CMGC_DYRK_DYRK1_DYRK1A_ST	P04637	TP53	Q13627	DYRK1A	S315	S315C	315	Missense	central	0	yes	40.613	0.000	EPSD	TCGA;ICGC;COSMIC	34.163	Loss
CMGC_DYRK_DYRK1_DYRK1A_ST	P24385	CCND1	Q13627	DYRK1A	T286	P287R	287	Missense	proximal	1	no	45.823	30.742	PhosphoSitePlus	TCGA;ICGC;COSMIC;GDSC;CCLE	34.163	Loss
CMGC_DYRK_DYRK1_DYRK1A_ST	P24385	CCND1	Q13627	DYRK1A	T286	P287T	287	Missense	proximal	1	no	45.823	23.445	PhosphoSitePlus	TCGA;ICGC;COSMIC;CCLE	34.163	Loss
CMGC_DYRK_DYRK1_DYRK1A_ST	P24385	CCND1	Q13627	DYRK1A	T286	P287L	287	Missense	proximal	1	no	45.823	3.492	PhosphoSitePlus	TCGA;ICGC;COSMIC;GDSC;CCLE	34.163	Loss
CMGC_DYRK_DYRK1_DYRK1A_ST	P24385	CCND1	Q13627	DYRK1A	T286	D282H	282	Missense	distal	-4	no	45.823	45.821	PhosphoSitePlus	TCGA;ICGC;COSMIC	34.163	Down-regulation
CMGC_DYRK_DYRK1_DYRK1A_ST	P24385	CCND1	Q13627	DYRK1A	T286	V290M	290	Missense	distal	4	no	45.823	44.377	PhosphoSitePlus	TCGA;ICGC	34.163	Down-regulation
CMGC_DYRK_DYRK1_DYRK1A_ST	P24385	CCND1	Q13627	DYRK1A	T286	P287H	287	Missense	proximal	1	no	45.823	-1.420	PhosphoSitePlus	TCGA;ICGC;COSMIC	34.163	Loss
CMGC_DYRK_DYRK1_DYRK1A_ST	P24385	CCND1	Q13627	DYRK1A	T286	T286R	286	Missense	central	0	yes	45.823	0.000	PhosphoSitePlus	TCGA;ICGC;COSMIC	34.163	Loss
CMGC_DYRK_DYRK1_DYRK1A_ST	P24385	CCND1	Q13627	DYRK1A	T286	V293G	293	Missense	distal	7	no	45.823	44.012	PhosphoSitePlus	TCGA;ICGC;COSMIC;CCLE	34.163	Down-regulation
CMGC_DYRK_DYRK1_DYRK1A_ST	P24385	CCND1	Q13627	DYRK1A	T286	T286I	286	Missense	central	0	yes	45.823	0.000	PhosphoSitePlus	TCGA;ICGC;COSMIC	34.163	Loss
CMGC_DYRK_DYRK1_DYRK1A_ST	P24385	CCND1	Q13627	DYRK1A	T286	P287S	287	Missense	proximal	1	no	45.823	23.870	PhosphoSitePlus	TCGA;ICGC;COSMIC	34.163	Loss
CMGC_DYRK_DYRK1_DYRK1A_ST	P24385	CCND1	Q13627	DYRK1A	T286	V281E	281	Missense	distal	-5	no	45.823	45.214	PhosphoSitePlus	TCGA;ICGC;COSMIC	34.163	Down-regulation
CMGC_DYRK_DYRK1_DYRK1A_ST	P24385	CCND1	Q13627	DYRK1A	T286	T286A	286	Missense	central	0	yes	45.823	0.000	PhosphoSitePlus	TCGA;ICGC;COSMIC	34.163	Loss
CMGC_DYRK_DYRK1_DYRK1A_ST	Q12778	FOXO1	Q13627	DYRK1A	S249	A255T	255	Missense	distal	6	no	44.475	44.430	EPSD	TCGA;ICGC;COSMIC	34.163	Down-regulation
CMGC_DYRK_DYRK1_DYRK1A_ST	Q12778	FOXO1	Q13627	DYRK1A	S249	R251S	251	Missense	proximal	2	no	44.475	43.975	EPSD	TCGA;ICGC;COSMIC	34.163	Down-regulation
CMGC_DYRK_DYRK1_DYRK1A_ST	Q12778	FOXO1	Q13627	DYRK1A	S249	P250L	250	Missense	proximal	1	no	44.475	2.144	EPSD	TCGA;ICGC;COSMIC	34.163	Loss
CMGC_DYRK_DYRK1_DYRK1A_ST	Q12778	FOXO1	Q13627	DYRK1A	S249	P250S	250	Missense	proximal	1	no	44.475	22.522	EPSD	TCGA;ICGC;COSMIC	34.163	Loss
CMGC_DYRK_DYRK1_DYRK1A_ST	Q12778	FOXO1	Q13627	DYRK1A	S249	S249Y	249	Missense	central	0	yes	44.475	0.000	EPSD	TCGA;ICGC;COSMIC	34.163	Loss
CMGC_DYRK_DYRK1_DYRK1A_ST	Q12778	FOXO1	Q13627	DYRK1A	S287	G289E	289	Missense	proximal	2	no	36.170	35.910	EPSD	TCGA;ICGC;COSMIC	34.163	Down-regulation
CMGC_DYRK_DYRK1_DYRK1A_ST	Q12778	FOXO1	Q13627	DYRK1A	S293	G289E	289	Missense	distal	-4	no	35.996	36.008	EPSD	TCGA;ICGC;COSMIC	34.163	Up-regulation
CMGC_DYRK_DYRK1_DYRK1A_ST	Q12778	FOXO1	Q13627	DYRK1A	S293	P299S	299	Missense	distal	6	no	35.996	36.005	EPSD	TCGA;ICGC;COSMIC	34.163	Up-regulation
CMGC_DYRK_DYRK1_DYRK1A_ST	Q12778	FOXO1	Q13627	DYRK1A	S298	P299S	299	Missense	proximal	1	no	42.421	20.468	EPSD	TCGA;ICGC;COSMIC	34.163	Loss
CMGC_DYRK_DYRK1_DYRK1A_ST	Q12778	FOXO1	Q13627	DYRK1A	T317	W310L	310	Missense	distal	-7	no	33.986	34.163	EPSD	TCGA;ICGC;COSMIC	34.163	Gain
CMGC_DYRK_DYRK1_DYRK1A_ST	Q12778	FOXO1	Q13627	DYRK1A	T317	R316Q	316	Missense	proximal	-1	no	33.986	34.517	EPSD	TCGA;ICGC;COSMIC	34.163	Gain
CMGC_DYRK_DYRK1_DYRK1A_ST	Q12778	FOXO1	Q13627	DYRK1A	S325	S329L	329	Missense	distal	4	no	32.960	34.810	EPSD	TCGA;ICGC;COSMIC	34.163	Gain
CMGC_DYRK_DYRK1_DYRK1A_ST	Q12778	FOXO1	Q13627	DYRK1A	S325	T323A	323	Missense	proximal	-2	no	32.960	34.306	EPSD	TCGA;ICGC;COSMIC	34.163	Gain
CMGC_DYRK_DYRK1_DYRK1A_ST	Q12778	FOXO1	Q13627	DYRK1A	S329	M332I	332	Missense	distal	3	no	54.730	54.728	PhosphoSitePlus	TCGA;COSMIC	34.163	Down-regulation
CMGC_DYRK_DYRK1_DYRK1A_ST	Q12778	FOXO1	Q13627	DYRK1A	S329	G326R	326	Missense	distal	-3	no	54.730	63.924	PhosphoSitePlus	TCGA;ICGC;COSMIC	34.163	Up-regulation
CMGC_DYRK_DYRK1_DYRK1A_ST	Q12778	FOXO1	Q13627	DYRK1A	S329	S329L	329	Missense	central	0	yes	54.730	0.000	PhosphoSitePlus	TCGA;ICGC;COSMIC	34.163	Loss
CMGC_DYRK_DYRK1_DYRK1A_ST	Q12778	FOXO1	Q13627	DYRK1A	S329	T323A	323	Missense	distal	-6	no	54.730	55.068	PhosphoSitePlus	TCGA;ICGC;COSMIC	34.163	Up-regulation
CMGC_DYRK_DYRK1_DYRK1A_ST	O76039	CDKL5	Q13627	DYRK1A	S308	A311S	311	Missense	distal	3	no	54.170	54.361	PhosphoSitePlus	TCGA;ICGC;COSMIC	34.163	Up-regulation
CMGC_DYRK_DYRK1_DYRK1A_ST	O76039	CDKL5	Q13627	DYRK1A	S308	D304N	304	Missense	distal	-4	no	54.170	54.174	PhosphoSitePlus	TCGA;ICGC;COSMIC	34.163	Up-regulation
CMGC_DYRK_DYRK1_DYRK1A_ST	O76039	CDKL5	Q13627	DYRK1A	S308	K314Q	314	Missense	distal	6	no	54.170	54.106	PhosphoSitePlus	TCGA;ICGC;COSMIC	34.163	Down-regulation
CMGC_DYRK_DYRK1_DYRK1A_ST	O76039	CDKL5	Q13627	DYRK1A	S308	P307R	307	Missense	proximal	-1	no	54.170	53.638	PhosphoSitePlus	TCGA;ICGC;COSMIC	34.163	Down-regulation
CMGC_DYRK_DYRK1_DYRK1A_ST	O76039	CDKL5	Q13627	DYRK1A	S308	R305C	305	Missense	distal	-3	no	54.170	30.665	PhosphoSitePlus	TCGA;ICGC;COSMIC	34.163	Loss
CMGC_DYRK_DYRK1_DYRK1A_ST	O76039	CDKL5	Q13627	DYRK1A	S308	P315L	315	Missense	distal	7	no	54.170	55.829	PhosphoSitePlus	TCGA;ICGC;COSMIC	34.163	Up-regulation
CMGC_DYRK_DYRK1_DYRK1A_ST	O76039	CDKL5	Q13627	DYRK1A	S343	I346V	346	Missense	distal	3	no	34.654	34.519	EPSD	TCGA;ICGC;COSMIC	34.163	Down-regulation
CMGC_DYRK_DYRK1_DYRK1A_ST	O76039	CDKL5	Q13627	DYRK1A	S377	P378A	378	Missense	proximal	1	no	37.916	7.771	EPSD	TCGA	34.163	Loss
CMGC_DYRK_DYRK1_DYRK1A_ST	O76039	CDKL5	Q13627	DYRK1A	S377	G373V	373	Missense	distal	-4	no	37.916	37.904	EPSD	TCGA;ICGC;COSMIC	34.163	Down-regulation
CMGC_DYRK_DYRK1_DYRK1A_ST	O76039	CDKL5	Q13627	DYRK1A	S377	T383A	383	Missense	distal	6	no	37.916	37.961	EPSD	TCGA;ICGC;COSMIC	34.163	Up-regulation
CMGC_DYRK_DYRK1_DYRK1A_ST	O76039	CDKL5	Q13627	DYRK1A	S377	A372T	372	Missense	distal	-5	no	37.916	37.908	EPSD	TCGA	34.163	Down-regulation
CMGC_DYRK_DYRK1_DYRK1A_ST	O76039	CDKL5	Q13627	DYRK1A	S479	A486D	486	Missense	distal	7	no	41.618	41.687	EPSD	TCGA;ICGC;COSMIC	34.163	Up-regulation
CMGC_DYRK_DYRK1_DYRK1A_ST	O76039	CDKL5	Q13627	DYRK1A	S479	Y482C	482	Missense	distal	3	no	41.618	41.656	EPSD	TCGA;ICGC;COSMIC	34.163	Up-regulation
CMGC_DYRK_DYRK1_DYRK1A_ST	O76039	CDKL5	Q13627	DYRK1A	S529	P530A	530	Missense	proximal	1	no	51.791	21.646	EPSD	TCGA;ICGC;COSMIC	34.163	Loss
CMGC_DYRK_DYRK1_DYRK1A_ST	O76039	CDKL5	Q13627	DYRK1A	T531	P530A	530	Missense	proximal	-1	no	36.608	36.661	EPSD	TCGA;ICGC;COSMIC	34.163	Up-regulation
CMGC_DYRK_DYRK1_DYRK1A_ST	O76039	CDKL5	Q13627	DYRK1A	S681	S674T	674	Missense	distal	-7	no	38.784	38.563	EPSD	TCGA;ICGC;COSMIC	34.163	Down-regulation
CMGC_DYRK_DYRK1_DYRK1A_ST	O76039	CDKL5	Q13627	DYRK1A	S681	S674F	674	Missense	distal	-7	no	38.784	39.886	EPSD	TCGA;ICGC;COSMIC	34.163	Up-regulation
CMGC_DYRK_DYRK1_DYRK1A_ST	O76039	CDKL5	Q13627	DYRK1A	S681	R678C	678	Missense	distal	-3	no	38.784	15.279	EPSD	TCGA;ICGC;COSMIC	34.163	Loss
CMGC_DYRK_DYRK1_DYRK1A_ST	O76039	CDKL5	Q13627	DYRK1A	S681	D688G	688	Missense	distal	7	no	38.784	37.084	EPSD	TCGA;ICGC;COSMIC	34.163	Down-regulation
CMGC_DYRK_DYRK1_DYRK1A_ST	O76039	CDKL5	Q13627	DYRK1A	S681	S681P	681	Missense	central	0	yes	38.784	0.000	EPSD	TCGA;ICGC	34.163	Loss
CMGC_DYRK_DYRK1_DYRK1A_ST	O76039	CDKL5	Q13627	DYRK1A	S714	F715L	715	Missense	proximal	1	no	36.380	11.948	EPSD	TCGA;ICGC	34.163	Loss
CMGC_DYRK_DYRK1_DYRK1A_ST	O76039	CDKL5	Q13627	DYRK1A	S714	P709Q	709	Missense	distal	-5	no	36.380	35.704	EPSD	TCGA;ICGC;COSMIC	34.163	Down-regulation
CMGC_DYRK_DYRK1_DYRK1A_ST	O76039	CDKL5	Q13627	DYRK1A	S714	P707H	707	Missense	distal	-7	no	36.380	36.490	EPSD	TCGA;ICGC;COSMIC	34.163	Up-regulation
CMGC_DYRK_DYRK1_DYRK1A_ST	O76039	CDKL5	Q13627	DYRK1A	S720	F715L	715	Missense	distal	-5	no	52.932	53.496	EPSD	TCGA;ICGC	34.163	Up-regulation
CMGC_DYRK_DYRK1_DYRK1A_ST	O76039	CDKL5	Q13627	DYRK1A	S720	S726Y	726	Missense	distal	6	no	52.932	53.048	EPSD	TCGA;ICGC	34.163	Up-regulation
CMGC_DYRK_DYRK1_DYRK1A_ST	O76039	CDKL5	Q13627	DYRK1A	S761	D757Y	757	Missense	distal	-4	no	34.273	34.243	EPSD	TCGA	34.163	Down-regulation
CMGC_DYRK_DYRK1_DYRK1A_ST	O76039	CDKL5	Q13627	DYRK1A	S761	A755T	755	Missense	distal	-6	no	34.273	33.935	EPSD	TCGA;ICGC;COSMIC	34.163	Loss
CMGC_DYRK_DYRK1_DYRK1A_ST	O76039	CDKL5	Q13627	DYRK1A	T813	S812N	812	Missense	proximal	-1	no	36.353	37.212	EPSD	TCGA;ICGC;COSMIC	34.163	Up-regulation
CMGC_DYRK_DYRK1_DYRK1A_ST	O76039	CDKL5	Q13627	DYRK1A	T813	K806T	806	Missense	distal	-7	no	36.353	36.204	EPSD	TCGA;ICGC	34.163	Down-regulation
CMGC_DYRK_DYRK1_DYRK1A_ST	P37840	SNCA	Q13627	DYRK1A	T81	A76S	76	Missense	distal	-5	no	38.024	38.354	EPSD	TCGA;ICGC;COSMIC	34.163	Up-regulation
CMGC_DYRK_DYRK1_DYRK1A_ST	P37840	SNCA	Q13627	DYRK1A	T81	A76G	76	Missense	distal	-5	no	38.024	38.730	EPSD	TCGA;ICGC;COSMIC	34.163	Up-regulation
CMGC_DYRK_DYRK1_DYRK1A_ST	P37840	SNCA	Q13627	DYRK1A	S87	F94V	94	Missense	distal	7	no	53.617	52.562	PhosphoSitePlus	TCGA;ICGC;COSMIC	34.163	Down-regulation
CMGC_DYRK_DYRK1_DYRK1A_ST	Q05193	DNM1	Q13627	DYRK1A	S116	R123C	123	Missense	distal	7	no	32.587	36.323	EPSD	TCGA	34.163	Gain
CMGC_DYRK_DYRK1_DYRK1A_ST	Q05193	DNM1	Q13627	DYRK1A	S126	R123C	123	Missense	distal	-3	no	38.404	14.899	EPSD	TCGA	34.163	Loss
CMGC_DYRK_DYRK1_DYRK1A_ST	Q05193	DNM1	Q13627	DYRK1A	T274	P275S	275	Missense	proximal	1	no	47.343	25.390	EPSD	TCGA;ICGC;COSMIC	34.163	Loss
CMGC_DYRK_DYRK1_DYRK1A_ST	Q05193	DNM1	Q13627	DYRK1A	T353	Q350K	350	Missense	distal	-3	no	31.902	37.809	EPSD	TCGA;ICGC;COSMIC	34.163	Gain
CMGC_DYRK_DYRK1_DYRK1A_ST	Q05193	DNM1	Q13627	DYRK1A	S774	P769L	769	Missense	distal	-5	no	40.955	39.519	EPSD	TCGA;ICGC;COSMIC	34.163	Down-regulation
CMGC_DYRK_DYRK1_DYRK1A_ST	Q05193	DNM1	Q13627	DYRK1A	S851	R854C	854	Missense	distal	3	no	40.410	40.308	EPSD	TCGA	34.163	Down-regulation
CMGC_DYRK_DYRK1_DYRK1A_ST	Q05193	DNM1	Q13627	DYRK1A	S851	R854H	854	Missense	distal	3	no	40.410	40.251	EPSD	TCGA;ICGC	34.163	Down-regulation
CMGC_DYRK_DYRK1_DYRK1A_ST	Q05193	DNM1	Q13627	DYRK1A	S851	R846Q	846	Missense	distal	-5	no	40.410	39.258	EPSD	TCGA;COSMIC;GDSC;CCLE	34.163	Down-regulation
CMGC_DYRK_DYRK1_DYRK1A_ST	Q05193	DNM1	Q13627	DYRK1A	S857	R854C	854	Missense	distal	-3	no	64.607	41.102	PhosphoSitePlus	TCGA	34.163	Down-regulation
CMGC_DYRK_DYRK1_DYRK1A_ST	Q05193	DNM1	Q13627	DYRK1A	S857	R854H	854	Missense	distal	-3	no	64.607	49.274	PhosphoSitePlus	TCGA;ICGC	34.163	Down-regulation
CMGC_DYRK_HIPK_HIPK1_ST	O60829	PAGE4	Q86Z02	HIPK1	T51	P44L	44	Missense	distal	-7	no	8.683	8.560	PhosphoSitePlus	TCGA;ICGC;COSMIC	1.785	Down-regulation
CMGC_DYRK_HIPK_HIPK1_ST	O60829	PAGE4	Q86Z02	HIPK1	T51	R57C	57	Missense	distal	6	no	8.683	8.649	PhosphoSitePlus	TCGA;ICGC	1.785	Down-regulation
CMGC_DYRK_HIPK_HIPK1_ST	O60829	PAGE4	Q86Z02	HIPK1	T51	E55K	55	Missense	distal	4	no	8.683	8.600	PhosphoSitePlus	TCGA;ICGC;COSMIC	1.785	Down-regulation
CMGC_DYRK_HIPK_HIPK1_ST	O60829	PAGE4	Q86Z02	HIPK1	S73	K70N	70	Missense	distal	-3	no	1.967	1.976	EPSD	TCGA;ICGC;COSMIC	1.785	Up-regulation
CMGC_DYRK_HIPK_HIPK1_ST	O60829	PAGE4	Q86Z02	HIPK1	S73	G78C	78	Missense	distal	5	no	1.967	1.869	EPSD	TCGA;ICGC;COSMIC	1.785	Down-regulation
CMGC_DYRK_HIPK_HIPK1_ST	O60829	PAGE4	Q86Z02	HIPK1	S73	R72Q	72	Missense	proximal	-1	no	1.967	1.915	EPSD	TCGA;ICGC;COSMIC;GDSC;CCLE	1.785	Down-regulation
CMGC_DYRK_HIPK_HIPK1_ST	O60829	PAGE4	Q86Z02	HIPK1	S73	D67H	67	Missense	distal	-6	no	1.967	2.096	EPSD	TCGA;ICGC;COSMIC	1.785	Up-regulation
CMGC_DYRK_HIPK_HIPK1_ST	O60829	PAGE4	Q86Z02	HIPK1	T85	A92V	92	Missense	distal	7	no	3.862	3.850	EPSD	TCGA;ICGC;COSMIC	1.785	Down-regulation
CMGC_DYRK_HIPK_HIPK1_ST	O60829	PAGE4	Q86Z02	HIPK1	T85	G78C	78	Missense	distal	-7	no	3.862	3.844	EPSD	TCGA;ICGC;COSMIC	1.785	Down-regulation
CMGC_DYRK_HIPK_HIPK1_ST	O60829	PAGE4	Q86Z02	HIPK1	T85	P89L	89	Missense	distal	4	no	3.862	3.933	EPSD	TCGA;ICGC;COSMIC	1.785	Up-regulation
CMGC_DYRK_HIPK_HIPK1_ST	O60829	PAGE4	Q86Z02	HIPK1	T85	P86A	86	Missense	proximal	1	no	3.862	0.557	EPSD	TCGA;ICGC;COSMIC	1.785	Loss
CMGC_DYRK_HIPK_HIPK1_ST	O60829	PAGE4	Q86Z02	HIPK1	T85	P87T	87	Missense	proximal	2	no	3.862	3.412	EPSD	TCGA;ICGC;COSMIC	1.785	Down-regulation
CMGC_DYRK_HIPK_HIPK1_ST	O60829	PAGE4	Q86Z02	HIPK1	T85	P86L	86	Missense	proximal	1	no	3.862	0.488	EPSD	TCGA;ICGC;COSMIC	1.785	Loss
Other_NEK_NEK11_NEK11_ST	P30304	CDC25A	Q8NG66	NEK11	S76	S69T	69	Missense	distal	-7	no	3.375	3.378	EPSD	TCGA;ICGC;COSMIC	2.788	Up-regulation
Other_NEK_NEK11_NEK11_ST	P30304	CDC25A	Q8NG66	NEK11	S76	R73K	73	Missense	distal	-3	no	3.375	3.409	EPSD	TCGA;ICGC;COSMIC	2.788	Up-regulation
Other_NEK_NEK11_NEK11_ST	P30304	CDC25A	Q8NG66	NEK11	S76	N70S	70	Missense	distal	-6	no	3.375	3.443	EPSD	TCGA;ICGC;COSMIC	2.788	Up-regulation
Other_NEK_NEK11_NEK11_ST	P30304	CDC25A	Q8NG66	NEK11	S76	E78K	78	Missense	proximal	2	no	3.375	3.211	EPSD	TCGA;ICGC;COSMIC	2.788	Down-regulation
Other_NEK_NEK11_NEK11_ST	P30304	CDC25A	Q8NG66	NEK11	S79	R73K	73	Missense	distal	-6	no	9.118	9.143	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	2.788	Up-regulation
Other_NEK_NEK11_NEK11_ST	P30304	CDC25A	Q8NG66	NEK11	S79	E78K	78	Missense	proximal	-1	no	9.118	8.518	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	2.788	Down-regulation
Other_NEK_NEK11_NEK11_ST	P30304	CDC25A	Q8NG66	NEK11	S82	D87Y	87	Missense	distal	5	no	9.075	8.968	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	2.788	Down-regulation
Other_NEK_NEK11_NEK11_ST	P30304	CDC25A	Q8NG66	NEK11	S82	P89L	89	Missense	distal	7	no	9.075	9.112	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	2.788	Up-regulation
Other_NEK_NEK11_NEK11_ST	P30304	CDC25A	Q8NG66	NEK11	S82	E78K	78	Missense	distal	-4	no	9.075	8.715	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	2.788	Down-regulation
Other_NEK_NEK11_NEK11_ST	P30304	CDC25A	Q8NG66	NEK11	S88	D87Y	87	Missense	proximal	-1	no	8.782	7.999	PhosphoSitePlus;EPSD	TCGA;ICGC;COSMIC	2.788	Down-regulation
Other_NEK_NEK11_NEK11_ST	P30304	CDC25A	Q8NG66	NEK11	S88	P89L	89	Missense	proximal	1	no	8.782	8.766	PhosphoSitePlus;EPSD	TCGA;ICGC;COSMIC	2.788	Down-regulation
Other_NEK_NEK11_NEK11_ST	P30304	CDC25A	Q8NG66	NEK11	S88	P91S	91	Missense	distal	3	no	8.782	8.695	PhosphoSitePlus;EPSD	TCGA;ICGC	2.788	Down-regulation
Other_NEK_NEK11_NEK11_ST	P30304	CDC25A	Q8NG66	NEK11	S122	R121S	121	Missense	proximal	-1	no	2.709	2.895	EPSD	TCGA;ICGC;COSMIC	2.788	Gain
Other_NEK_NEK11_NEK11_ST	P30304	CDC25A	Q8NG66	NEK11	S263	R270P	270	Missense	distal	7	no	3.708	3.736	EPSD	TCGA;ICGC;COSMIC;GDSC;CCLE	2.788	Up-regulation
Other_NEK_NEK11_NEK11_ST	P30304	CDC25A	Q8NG66	NEK11	S293	S298N	298	Missense	distal	5	no	3.687	3.749	EPSD	TCGA;ICGC;COSMIC	2.788	Up-regulation
Other_NEK_NEK11_NEK11_ST	P30304	CDC25A	Q8NG66	NEK11	S320	S317F	317	Missense	distal	-3	no	3.121	3.071	EPSD	TCGA;ICGC;COSMIC	2.788	Down-regulation
Other_NEK_NEK11_NEK11_ST	P30304	CDC25A	Q8NG66	NEK11	S342	L337I	337	Missense	distal	-5	no	4.210	4.121	EPSD	TCGA;ICGC	2.788	Down-regulation
Other_NEK_NEK11_NEK11_ST	P54132	BLM	Q8NG66	NEK11	S17	R15C	15	Missense	proximal	-2	no	3.432	3.488	EPSD	TCGA;ICGC;COSMIC	2.788	Up-regulation
Other_NEK_NEK11_NEK11_ST	P54132	BLM	Q8NG66	NEK11	S28	P30L	30	Missense	proximal	2	no	3.082	2.995	EPSD	TCGA;ICGC;COSMIC	2.788	Down-regulation
Other_NEK_NEK11_NEK11_ST	P54132	BLM	Q8NG66	NEK11	S28	S33L	33	Missense	distal	5	no	3.082	2.913	EPSD	TCGA;ICGC;COSMIC	2.788	Down-regulation
Other_NEK_NEK11_NEK11_ST	P54132	BLM	Q8NG66	NEK11	S48	S48F	48	Missense	central	0	yes	3.483	0.000	EPSD	TCGA;ICGC;COSMIC	2.788	Loss
Other_NEK_NEK11_NEK11_ST	P54132	BLM	Q8NG66	NEK11	S168	S175I	175	Missense	distal	7	no	3.481	3.560	EPSD	TCGA;ICGC;COSMIC	2.788	Up-regulation
Other_NEK_NEK11_NEK11_ST	P54132	BLM	Q8NG66	NEK11	S315	S310C	310	Missense	distal	-5	no	3.222	3.143	EPSD	TCGA;ICGC	2.788	Down-regulation
Other_NEK_NEK11_NEK11_ST	P54132	BLM	Q8NG66	NEK11	S338	L335F	335	Missense	distal	-3	no	8.770	8.808	PhosphoSitePlus	TCGA;ICGC;COSMIC	2.788	Up-regulation
Other_NEK_NEK11_NEK11_ST	P54132	BLM	Q8NG66	NEK11	S338	D340Y	340	Missense	proximal	2	no	8.770	8.560	PhosphoSitePlus	TCGA;ICGC;COSMIC	2.788	Down-regulation
Other_NEK_NEK11_NEK11_ST	P54132	BLM	Q8NG66	NEK11	S349	M348V	348	Missense	proximal	-1	no	3.252	2.925	EPSD	TCGA;ICGC;COSMIC	2.788	Down-regulation
Other_NEK_NEK11_NEK11_ST	P54132	BLM	Q8NG66	NEK11	S349	M350I	350	Missense	proximal	1	no	3.252	3.260	EPSD	TCGA;ICGC;COSMIC	2.788	Up-regulation
Other_NEK_NEK11_NEK11_ST	P54132	BLM	Q8NG66	NEK11	S434	D433H	433	Missense	proximal	-1	no	2.917	2.120	EPSD	TCGA;ICGC;COSMIC	2.788	Loss
Other_NEK_NEK11_NEK11_ST	P54132	BLM	Q8NG66	NEK11	S434	R431K	431	Missense	distal	-3	no	2.917	2.951	EPSD	TCGA;ICGC;COSMIC	2.788	Up-regulation
Other_NEK_NEK11_NEK11_ST	P54132	BLM	Q8NG66	NEK11	S434	R429K	429	Missense	distal	-5	no	2.917	2.865	EPSD	TCGA;ICGC;COSMIC	2.788	Down-regulation
Other_NEK_NEK11_NEK11_ST	P54132	BLM	Q8NG66	NEK11	S434	P438H	438	Missense	distal	4	no	2.917	2.667	EPSD	TCGA;ICGC	2.788	Loss
Other_NEK_NEK11_NEK11_ST	P54132	BLM	Q8NG66	NEK11	S434	G437V	437	Missense	distal	3	no	2.917	2.856	EPSD	TCGA;ICGC;COSMIC	2.788	Down-regulation
Other_NEK_NEK11_NEK11_ST	P54132	BLM	Q8NG66	NEK11	S443	G447R	447	Missense	distal	4	no	4.037	3.466	EPSD	TCGA;ICGC	2.788	Down-regulation
Other_NEK_NEK11_NEK11_ST	P54132	BLM	Q8NG66	NEK11	S443	P438H	438	Missense	distal	-5	no	4.037	4.010	EPSD	TCGA;ICGC	2.788	Down-regulation
Other_NEK_NEK11_NEK11_ST	P54132	BLM	Q8NG66	NEK11	S443	G437V	437	Missense	distal	-6	no	4.037	4.079	EPSD	TCGA;ICGC;COSMIC	2.788	Up-regulation
Other_NEK_NEK11_NEK11_ST	P54132	BLM	Q8NG66	NEK11	S443	S449Y	449	Missense	distal	6	no	4.037	3.936	EPSD	TCGA;ICGC	2.788	Down-regulation
Other_NEK_NEK11_NEK11_ST	P54132	BLM	Q8NG66	NEK11	S462	S462Y	462	Missense	central	0	yes	3.738	0.000	EPSD	TCGA;ICGC;COSMIC	2.788	Loss
Other_NEK_NEK11_NEK11_ST	P54132	BLM	Q8NG66	NEK11	S464	S462Y	462	Missense	proximal	-2	no	3.943	3.909	EPSD	TCGA;ICGC;COSMIC	2.788	Down-regulation
Other_NEK_NEK11_NEK11_ST	P54132	BLM	Q8NG66	NEK11	T528	K535Q	535	Missense	distal	7	no	3.192	3.193	EPSD	TCGA;ICGC;COSMIC	2.788	Up-regulation
Other_NEK_NEK11_NEK11_ST	P54132	BLM	Q8NG66	NEK11	S539	E546Q	546	Missense	distal	7	no	3.884	3.889	EPSD	TCGA;ICGC;COSMIC	2.788	Up-regulation
Other_NEK_NEK11_NEK11_ST	P54132	BLM	Q8NG66	NEK11	S539	K535Q	535	Missense	distal	-4	no	3.884	3.692	EPSD	TCGA;ICGC;COSMIC	2.788	Down-regulation
Other_NEK_NEK11_NEK11_ST	P54132	BLM	Q8NG66	NEK11	S601	L600F	600	Missense	proximal	-1	no	2.848	3.391	EPSD	TCGA;ICGC;COSMIC	2.788	Up-regulation
Other_NEK_NEK11_NEK11_ST	P54132	BLM	Q8NG66	NEK11	S646	K653M	653	Missense	distal	7	no	3.176	3.236	EPSD	TCGA;ICGC;COSMIC	2.788	Up-regulation
Other_NEK_NEK11_NEK11_ST	P54132	BLM	Q8NG66	NEK11	S646	L647I	647	Missense	proximal	1	no	3.176	3.178	EPSD	TCGA;COSMIC	2.788	Up-regulation
Other_NEK_NEK11_NEK11_ST	P54132	BLM	Q8NG66	NEK11	S646	R643C	643	Missense	distal	-3	no	3.176	3.216	EPSD	TCGA;ICGC;COSMIC	2.788	Up-regulation
Other_NEK_NEK11_NEK11_ST	P54132	BLM	Q8NG66	NEK11	S646	K653N	653	Missense	distal	7	no	3.176	3.146	EPSD	TCGA;ICGC;COSMIC	2.788	Down-regulation
Other_NEK_NEK11_NEK11_ST	P54132	BLM	Q8NG66	NEK11	S1138	G1134E	1134	Missense	distal	-4	no	3.400	3.439	EPSD	TCGA;ICGC;COSMIC	2.788	Up-regulation
Other_NEK_NEK11_NEK11_ST	P54132	BLM	Q8NG66	NEK11	S1138	R1144I	1144	Missense	distal	6	no	3.400	3.399	EPSD	TCGA;ICGC;COSMIC	2.788	Down-regulation
Other_NEK_NEK11_NEK11_ST	P54132	BLM	Q8NG66	NEK11	S1138	L1145R	1145	Missense	distal	7	no	3.400	3.335	EPSD	TCGA;ICGC	2.788	Down-regulation
Other_NEK_NEK11_NEK11_ST	P54132	BLM	Q8NG66	NEK11	S1138	E1143K	1143	Missense	distal	5	no	3.400	3.257	EPSD	TCGA;ICGC;COSMIC	2.788	Down-regulation
Other_NEK_NEK11_NEK11_ST	P54132	BLM	Q8NG66	NEK11	S1138	G1132V	1132	Missense	distal	-6	no	3.400	3.442	EPSD	TCGA;ICGC;COSMIC	2.788	Up-regulation
Other_NEK_NEK11_NEK11_ST	P54132	BLM	Q8NG66	NEK11	S1280	S1280L	1280	Missense	central	0	yes	2.855	0.000	EPSD	TCGA;ICGC;COSMIC	2.788	Loss
Other_NEK_NEK11_NEK11_ST	P54132	BLM	Q8NG66	NEK11	S1310	G1308R	1308	Missense	proximal	-2	no	2.822	2.849	EPSD	TCGA;ICGC;COSMIC	2.788	Up-regulation
Other_NEK_NEK11_NEK11_ST	P54132	BLM	Q8NG66	NEK11	S1310	E1313D	1313	Missense	distal	3	no	2.822	2.914	EPSD	TCGA;ICGC;COSMIC	2.788	Up-regulation
TK_Jak_JAK2_Y	P78347	GTF2I	O60674	JAK2	Y248	Q250E	250	Missense	proximal	2	no	6.637	6.033	PhosphoSitePlus	TCGA;ICGC;COSMIC	5.995	Down-regulation
TK_Jak_JAK2_Y	P78347	GTF2I	O60674	JAK2	Y248	Y251C	251	Missense	distal	3	no	6.637	4.493	PhosphoSitePlus	TCGA;ICGC;COSMIC	5.995	Loss
TK_Jak_JAK2_Y	P62993	GRB2	O60674	JAK2	Y7	Y7D	7	Missense	central	0	yes	6.767	0.000	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	5.995	Loss
TK_Jak_JAK2_Y	P62993	GRB2	O60674	JAK2	Y7	A13V	13	Missense	distal	6	no	6.767	6.487	EPSD;PhosphoSitePlus	TCGA;ICGC	5.995	Down-regulation
TK_Jak_JAK2_Y	P62993	GRB2	O60674	JAK2	Y52	F47L	47	Missense	distal	-5	no	9.250	9.229	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	5.995	Down-regulation
TK_Jak_JAK2_Y	P62993	GRB2	O60674	JAK2	Y52	I53R	53	Missense	proximal	1	no	9.250	9.426	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	5.995	Up-regulation
TK_Jak_JAK2_Y	O14744	PRMT5	O60674	JAK2	Y297	P294S	294	Missense	distal	-3	no	9.120	9.923	EPSD;PhosphoSitePlus	TCGA	5.995	Up-regulation
TK_Jak_JAK2_Y	O14744	PRMT5	O60674	JAK2	Y304	D306H	306	Missense	proximal	2	no	8.666	10.737	EPSD;PhosphoSitePlus	TCGA;COSMIC	5.995	Up-regulation
TK_Jak_JAK2_Y	O14744	PRMT5	O60674	JAK2	Y307	D306H	306	Missense	proximal	-1	no	9.079	7.984	PhosphoSitePlus;EPSD	TCGA;COSMIC	5.995	Down-regulation
TK_Jak_JAK2_Y	Q9UGK3	STAP2	O60674	JAK2	Y310	Q306H	306	Missense	distal	-4	no	9.636	9.017	EPSD;PhosphoSitePlus	TCGA;ICGC	5.995	Down-regulation
TK_Jak_JAK2_Y	Q9UGK3	STAP2	O60674	JAK2	Y310	G317D	317	Missense	distal	7	no	9.636	9.577	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC;GDSC;CCLE	5.995	Down-regulation
TK_Jak_JAK2_Y	Q9UGK3	STAP2	O60674	JAK2	Y322	D326G	326	Missense	distal	4	no	9.562	9.308	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	5.995	Down-regulation
TK_Jak_JAK2_Y	Q9UGK3	STAP2	O60674	JAK2	Y322	P318L	318	Missense	distal	-4	no	9.562	9.107	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	5.995	Down-regulation
TK_Jak_JAK2_Y	Q9UGK3	STAP2	O60674	JAK2	Y322	G317D	317	Missense	distal	-5	no	9.562	9.601	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC;GDSC;CCLE	5.995	Up-regulation
TK_Jak_JAK2_Y	O60674	JAK2	O60674	JAK2	Y119	R122H	122	Missense	distal	3	no	13.126	12.601	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	5.995	Down-regulation
TK_Jak_JAK2_Y	O60674	JAK2	O60674	JAK2	Y119	R122L	122	Missense	distal	3	no	13.126	15.758	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	5.995	Up-regulation
TK_Jak_JAK2_Y	O60674	JAK2	O60674	JAK2	Y119	Y114C	114	Missense	distal	-5	no	13.126	13.176	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	5.995	Up-regulation
TK_Jak_JAK2_Y	O60674	JAK2	O60674	JAK2	Y119	S126N	126	Missense	distal	7	no	13.126	13.000	EPSD;PhosphoSitePlus	TCGA;COSMIC	5.995	Down-regulation
TK_Jak_JAK2_Y	O60674	JAK2	O60674	JAK2	Y201	Y201S	201	Missense	central	0	yes	6.956	0.000	EPSD	TCGA;COSMIC	5.995	Loss
TK_Jak_JAK2_Y	O60674	JAK2	O60674	JAK2	Y206	F209L	209	Missense	distal	3	no	5.513	7.538	EPSD	TCGA;COSMIC	5.995	Gain
TK_Jak_JAK2_Y	O60674	JAK2	O60674	JAK2	Y221	R215Q	215	Missense	distal	-6	no	11.172	11.443	EPSD	TCGA;ICGC;COSMIC	5.995	Up-regulation
TK_Jak_JAK2_Y	O60674	JAK2	O60674	JAK2	Y221	R228Q	228	Missense	distal	7	no	11.172	10.872	EPSD	TCGA;ICGC;COSMIC	5.995	Down-regulation
TK_Jak_JAK2_Y	O60674	JAK2	O60674	JAK2	Y221	K217N	217	Missense	distal	-4	no	11.172	10.234	EPSD	TCGA	5.995	Down-regulation
TK_Jak_JAK2_Y	O60674	JAK2	O60674	JAK2	Y570	R564Q	564	Missense	distal	-6	no	9.653	9.924	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	5.995	Up-regulation
TK_Jak_JAK2_Y	O60674	JAK2	O60674	JAK2	Y570	D569Y	569	Missense	proximal	-1	no	9.653	8.269	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	5.995	Down-regulation
TK_Jak_JAK2_Y	O60674	JAK2	O60674	JAK2	Y570	V563I	563	Missense	distal	-7	no	9.653	9.652	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC;GDSC;CCLE	5.995	Down-regulation
TK_Jak_JAK2_Y	O60674	JAK2	O60674	JAK2	Y637	K640N	640	Missense	distal	3	no	7.231	6.256	EPSD	TCGA;COSMIC;CCLE	5.995	Down-regulation
TK_Jak_JAK2_Y	O60674	JAK2	O60674	JAK2	Y637	T636I	636	Missense	proximal	-1	no	7.231	5.806	EPSD	TCGA;ICGC	5.995	Loss
TK_Jak_JAK2_Y	O60674	JAK2	O60674	JAK2	Y637	F631C	631	Missense	distal	-6	no	7.231	6.594	EPSD	TCGA;COSMIC	5.995	Down-regulation
TK_Jak_JAK2_Y	O60674	JAK2	O60674	JAK2	Y813	D820Y	820	Missense	distal	7	no	7.455	6.932	EPSD	TCGA;COSMIC	5.995	Down-regulation
TK_Jak_JAK2_Y	O60674	JAK2	O60674	JAK2	Y868	D869N	869	Missense	proximal	1	no	8.754	8.720	EPSD	TCGA;ICGC;COSMIC	5.995	Down-regulation
TK_Jak_JAK2_Y	O60674	JAK2	O60674	JAK2	Y868	P870L	870	Missense	proximal	2	no	8.754	7.296	EPSD	TCGA;ICGC;COSMIC	5.995	Down-regulation
TK_Jak_JAK2_Y	O60674	JAK2	O60674	JAK2	Y868	P870S	870	Missense	proximal	2	no	8.754	8.341	EPSD	TCGA;COSMIC	5.995	Down-regulation
TK_Jak_JAK2_Y	O60674	JAK2	O60674	JAK2	Y966	M964V	964	Missense	proximal	-2	no	8.263	7.543	EPSD	TCGA;COSMIC	5.995	Down-regulation
TK_Jak_JAK2_Y	O60674	JAK2	O60674	JAK2	Y966	Y972H	972	Missense	distal	6	no	8.263	8.448	EPSD	TCGA;COSMIC	5.995	Up-regulation
TK_Jak_JAK2_Y	O60674	JAK2	O60674	JAK2	Y972	Y972H	972	Missense	central	0	yes	7.210	0.000	EPSD	TCGA;COSMIC	5.995	Loss
TK_Jak_JAK2_Y	Q15910	EZH2	O60674	JAK2	Y23	R18C	18	Missense	distal	-5	no	6.182	6.283	EPSD	TCGA;ICGC;COSMIC	5.995	Up-regulation
TK_Jak_JAK2_Y	Q15910	EZH2	O60674	JAK2	Y23	Q28H	28	Missense	distal	5	no	6.182	7.700	EPSD	TCGA;ICGC	5.995	Up-regulation
TK_Jak_JAK2_Y	Q15910	EZH2	O60674	JAK2	Y23	R25Q	25	Missense	proximal	2	no	6.182	5.626	EPSD	TCGA;ICGC;COSMIC	5.995	Loss
TK_Jak_JAK2_Y	P42229	STAT5A	O60674	JAK2	Y683	Y683S	683	Missense	central	0	yes	6.063	0.000	EPSD	TCGA;COSMIC	5.995	Loss
TK_Jak_JAK2_Y	P42229	STAT5A	O60674	JAK2	Y694	Q698P	698	Missense	distal	4	no	12.625	12.875	PhosphoSitePlus	TCGA;ICGC	5.995	Up-regulation
TK_Jak_JAK2_Y	P41597	CCR2	O60674	JAK2	Y139	L134Q	134	Missense	distal	-5	no	9.206	9.139	PhosphoSitePlus	TCGA;ICGC;COSMIC	5.995	Down-regulation
TK_Jak_JAK2_Y	P41597	CCR2	O60674	JAK2	Y139	D137N	137	Missense	proximal	-2	no	9.206	7.255	PhosphoSitePlus	TCGA;ICGC;COSMIC	5.995	Down-regulation
TK_Jak_JAK2_Y	P41597	CCR2	O60674	JAK2	Y139	T135S	135	Missense	distal	-4	no	9.206	9.625	PhosphoSitePlus	TCGA;ICGC;COSMIC	5.995	Up-regulation
TK_Jak_JAK2_Y	P28482	MAPK1	O60674	JAK2	Y187	R191C	191	Missense	distal	4	no	12.522	11.989	PhosphoSitePlus	TCGA;ICGC;COSMIC	5.995	Down-regulation
TK_Jak_JAK2_Y	P28482	MAPK1	O60674	JAK2	Y187	R191H	191	Missense	distal	4	no	12.522	13.394	PhosphoSitePlus	TCGA;ICGC;COSMIC	5.995	Up-regulation
TK_Jak_JAK2_Y	O14543	SOCS3	O60674	JAK2	Y204	V197I	197	Missense	distal	-7	no	6.124	6.123	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	5.995	Down-regulation
TK_Jak_JAK2_Y	O14543	SOCS3	O60674	JAK2	Y204	H200R	200	Missense	distal	-4	no	6.124	7.040	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	5.995	Up-regulation
TK_Jak_JAK2_Y	O14543	SOCS3	O60674	JAK2	Y204	P211L	211	Missense	distal	7	no	6.124	6.007	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	5.995	Down-regulation
TK_Jak_JAK2_Y	Q15118	PDK1	O60674	JAK2	Y243	E249K	249	Missense	distal	6	no	9.334	10.078	PhosphoSitePlus	TCGA;ICGC;COSMIC	5.995	Up-regulation
TK_Jak_JAK2_Y	Q15118	PDK1	O60674	JAK2	Y243	Y244C	244	Missense	proximal	1	no	9.334	9.421	PhosphoSitePlus	TCGA;ICGC	5.995	Up-regulation
TK_Jak_JAK2_Y	Q15118	PDK1	O60674	JAK2	Y243	R237W	237	Missense	distal	-6	no	9.334	8.711	PhosphoSitePlus	TCGA;ICGC;COSMIC	5.995	Down-regulation
TK_Jak_JAK2_Y	Q15118	PDK1	O60674	JAK2	Y243	S247C	247	Missense	distal	4	no	9.334	8.446	PhosphoSitePlus	TCGA;ICGC;COSMIC	5.995	Down-regulation
TK_Jak_JAK2_Y	Q15118	PDK1	O60674	JAK2	Y403	A406D	406	Missense	distal	3	no	6.722	6.262	EPSD	TCGA;ICGC;COSMIC	5.995	Down-regulation
TK_Jak_JAK2_Y	P27361	MAPK3	O60674	JAK2	Y81	E77K	77	Missense	distal	-4	no	5.280	6.152	EPSD	TCGA;ICGC;COSMIC	5.995	Gain
TK_Jak_JAK2_Y	P27361	MAPK3	O60674	JAK2	Y204	R211W	211	Missense	distal	7	no	13.438	12.910	PhosphoSitePlus	TCGA	5.995	Down-regulation
TK_Jak_JAK2_Y	Q9UQC2	GAB2	O60674	JAK2	Y48	Y48C	48	Missense	central	0	yes	6.170	0.000	EPSD	TCGA;ICGC;COSMIC	5.995	Loss
TK_Jak_JAK2_Y	Q9UQC2	GAB2	O60674	JAK2	Y48	H53Y	53	Missense	distal	5	no	6.170	6.678	EPSD	TCGA;ICGC;COSMIC	5.995	Up-regulation
TK_Jak_JAK2_Y	Q9UQC2	GAB2	O60674	JAK2	Y614	G610S	610	Missense	distal	-4	no	7.068	7.035	EPSD	TCGA;COSMIC;CCLE	5.995	Down-regulation
TK_Jak_JAK2_Y	Q9UQC2	GAB2	O60674	JAK2	Y614	P621Q	621	Missense	distal	7	no	7.068	6.803	EPSD	TCGA;COSMIC	5.995	Down-regulation
TK_Jak_JAK2_Y	Q9UQC2	GAB2	O60674	JAK2	Y614	A616D	616	Missense	proximal	2	no	7.068	4.326	EPSD	TCGA;COSMIC	5.995	Loss
TK_Jak_JAK2_Y	Q99683	MAP3K5	O60674	JAK2	Y718	L722P	722	Missense	distal	4	no	10.831	10.897	PhosphoSitePlus	TCGA;ICGC;COSMIC	5.995	Up-regulation
TK_Jak_JAK2_Y	Q99683	MAP3K5	O60674	JAK2	Y982	E981K	981	Missense	proximal	-1	no	6.315	5.152	EPSD	TCGA;COSMIC	5.995	Loss
TK_Jak_JAK2_Y	Q99683	MAP3K5	O60674	JAK2	Y982	S977T	977	Missense	distal	-5	no	6.315	6.403	EPSD	TCGA;COSMIC	5.995	Up-regulation
TK_Jak_JAK2_Y	Q99683	MAP3K5	O60674	JAK2	Y982	S977I	977	Missense	distal	-5	no	6.315	6.417	EPSD	TCGA;COSMIC	5.995	Up-regulation
TK_Jak_JAK2_Y	Q99683	MAP3K5	O60674	JAK2	Y982	Y982H	982	Missense	central	0	yes	6.315	0.000	EPSD	TCGA;COSMIC	5.995	Loss
TK_Jak_JAK2_Y	P42224	STAT1	O60674	JAK2	Y68	R70H	70	Missense	proximal	2	no	5.598	6.787	EPSD	TCGA;ICGC;COSMIC	5.995	Gain
TK_Jak_JAK2_Y	P42224	STAT1	O60674	JAK2	Y170	D165A	165	Missense	distal	-5	no	6.275	6.166	EPSD	TCGA;ICGC;COSMIC	5.995	Down-regulation
TK_Jak_JAK2_Y	P42224	STAT1	O60674	JAK2	Y170	Q167R	167	Missense	distal	-3	no	6.275	4.053	EPSD	TCGA;ICGC;COSMIC	5.995	Loss
TK_Jak_JAK2_Y	P42224	STAT1	O60674	JAK2	Y203	K201M	201	Missense	proximal	-2	no	6.335	7.843	EPSD	TCGA;ICGC;COSMIC	5.995	Up-regulation
TK_Jak_JAK2_Y	P42224	STAT1	O60674	JAK2	Y203	L199V	199	Missense	distal	-4	no	6.335	6.091	EPSD	TCGA;ICGC;COSMIC	5.995	Down-regulation
TK_Jak_JAK2_Y	P42224	STAT1	O60674	JAK2	Y203	N208S	208	Missense	distal	5	no	6.335	4.634	EPSD	TCGA;ICGC;COSMIC	5.995	Loss
TK_Jak_JAK2_Y	P42224	STAT1	O60674	JAK2	Y203	Y203H	203	Missense	central	0	yes	6.335	0.000	EPSD	TCGA;ICGC	5.995	Loss
TK_Jak_JAK2_Y	P42224	STAT1	O60674	JAK2	Y701	E705K	705	Missense	distal	4	no	8.804	9.144	PhosphoSitePlus	TCGA;ICGC;COSMIC	5.995	Up-regulation
CMGC_CDK_CDK4_CDK4_ST	Q8IZL8	PELP1	P11802	CDK4	S25	S29L	29	Missense	distal	4	no	2.480	2.848	EPSD	TCGA;ICGC;COSMIC	2.642	Gain
CMGC_CDK_CDK4_CDK4_ST	Q8IZL8	PELP1	P11802	CDK4	S477	G484W	484	Missense	distal	7	no	9.117	9.126	PhosphoSitePlus	TCGA;COSMIC	2.642	Up-regulation
CMGC_CDK_CDK4_CDK4_ST	Q8IZL8	PELP1	P11802	CDK4	S477	G480E	480	Missense	distal	3	no	9.117	9.400	PhosphoSitePlus	TCGA;COSMIC	2.642	Up-regulation
CMGC_CDK_CDK4_CDK4_ST	Q8IZL8	PELP1	P11802	CDK4	S477	G480R	480	Missense	distal	3	no	9.117	9.679	PhosphoSitePlus	TCGA;COSMIC	2.642	Up-regulation
CMGC_CDK_CDK4_CDK4_ST	Q8IZL8	PELP1	P11802	CDK4	S477	P478S	478	Missense	proximal	1	no	9.117	2.930	PhosphoSitePlus	TCGA;COSMIC	2.642	Down-regulation
CMGC_CDK_CDK4_CDK4_ST	Q8IZL8	PELP1	P11802	CDK4	S481	G484W	484	Missense	distal	3	no	6.901	6.974	EPSD	TCGA;COSMIC	2.642	Up-regulation
CMGC_CDK_CDK4_CDK4_ST	Q8IZL8	PELP1	P11802	CDK4	S481	G480E	480	Missense	proximal	-1	no	6.901	6.575	EPSD	TCGA;COSMIC	2.642	Down-regulation
CMGC_CDK_CDK4_CDK4_ST	Q8IZL8	PELP1	P11802	CDK4	S481	G480R	480	Missense	proximal	-1	no	6.901	6.530	EPSD	TCGA;COSMIC	2.642	Down-regulation
CMGC_CDK_CDK4_CDK4_ST	Q8IZL8	PELP1	P11802	CDK4	S481	P478S	478	Missense	distal	-3	no	6.901	6.976	EPSD	TCGA;COSMIC	2.642	Up-regulation
CMGC_CDK_CDK4_CDK4_ST	Q8IZL8	PELP1	P11802	CDK4	T488	A493V	493	Missense	distal	5	no	3.657	3.684	EPSD	TCGA;COSMIC	2.642	Up-regulation
CMGC_CDK_CDK4_CDK4_ST	Q8IZL8	PELP1	P11802	CDK4	T488	P494A	494	Missense	distal	6	no	3.657	3.737	EPSD	TCGA;COSMIC	2.642	Up-regulation
CMGC_CDK_CDK4_CDK4_ST	Q8IZL8	PELP1	P11802	CDK4	T488	A493T	493	Missense	distal	5	no	3.657	3.665	EPSD	TCGA;COSMIC	2.642	Up-regulation
CMGC_CDK_CDK4_CDK4_ST	Q8IZL8	PELP1	P11802	CDK4	S492	A493V	493	Missense	proximal	1	no	2.911	2.520	EPSD	TCGA;COSMIC	2.642	Loss
CMGC_CDK_CDK4_CDK4_ST	Q8IZL8	PELP1	P11802	CDK4	S492	P494A	494	Missense	proximal	2	no	2.911	2.971	EPSD	TCGA;COSMIC	2.642	Up-regulation
CMGC_CDK_CDK4_CDK4_ST	Q8IZL8	PELP1	P11802	CDK4	S492	A493T	493	Missense	proximal	1	no	2.911	3.322	EPSD	TCGA;COSMIC	2.642	Up-regulation
CMGC_CDK_CDK4_CDK4_ST	Q8IZL8	PELP1	P11802	CDK4	S515	G513R	513	Missense	proximal	-2	no	2.639	2.715	EPSD	TCGA;COSMIC	2.642	Gain
CMGC_CDK_CDK4_CDK4_ST	Q8IZL8	PELP1	P11802	CDK4	S515	K512N	512	Missense	distal	-3	no	2.639	2.657	EPSD	TCGA;COSMIC	2.642	Gain
CMGC_CDK_CDK4_CDK4_ST	Q8IZL8	PELP1	P11802	CDK4	S515	V521M	521	Missense	distal	6	no	2.639	2.650	EPSD	TCGA;COSMIC	2.642	Gain
CMGC_CDK_CDK4_CDK4_ST	Q8IZL8	PELP1	P11802	CDK4	T647	P650L	650	Missense	distal	3	no	9.108	8.209	EPSD	TCGA;COSMIC	2.642	Down-regulation
CMGC_CDK_CDK4_CDK4_ST	Q8IZL8	PELP1	P11802	CDK4	T647	P653S	653	Missense	distal	6	no	9.108	9.265	EPSD	TCGA;COSMIC	2.642	Up-regulation
CMGC_CDK_CDK4_CDK4_ST	Q8IZL8	PELP1	P11802	CDK4	S658	P653S	653	Missense	distal	-5	no	7.514	7.650	EPSD	TCGA;COSMIC	2.642	Up-regulation
CMGC_CDK_CDK4_CDK4_ST	Q8IZL8	PELP1	P11802	CDK4	S658	P659L	659	Missense	proximal	1	no	7.514	-0.065	EPSD	TCGA;COSMIC	2.642	Loss
CMGC_CDK_CDK4_CDK4_ST	Q8IZL8	PELP1	P11802	CDK4	S743	E736K	736	Missense	distal	-7	no	2.730	2.686	EPSD	TCGA;COSMIC	2.642	Down-regulation
CMGC_CDK_CDK4_CDK4_ST	Q8IZL8	PELP1	P11802	CDK4	S804	P797L	797	Missense	distal	-7	no	2.648	2.168	EPSD	TCGA;COSMIC	2.642	Loss
CMGC_CDK_CDK4_CDK4_ST	Q8IZL8	PELP1	P11802	CDK4	T807	P813L	813	Missense	distal	6	no	9.033	9.011	EPSD	TCGA;COSMIC;CCLE	2.642	Down-regulation
CMGC_CDK_CDK4_CDK4_ST	Q8IZL8	PELP1	P11802	CDK4	S991	P997S	997	Missense	distal	6	no	9.416	9.573	EPSD	TCGA;COSMIC;CCLE	2.642	Up-regulation
CMGC_CDK_CDK4_CDK4_ST	Q8IZL8	PELP1	P11802	CDK4	S991	P992L	992	Missense	proximal	1	no	9.416	1.836	EPSD	TCGA;COSMIC	2.642	Loss
CMGC_CDK_CDK4_CDK4_ST	Q8IZL8	PELP1	P11802	CDK4	S991	E990V	990	Missense	proximal	-1	no	9.416	9.540	EPSD	TCGA;COSMIC	2.642	Up-regulation
CMGC_CDK_CDK4_CDK4_ST	Q8IZL8	PELP1	P11802	CDK4	S1043	E1038D	1038	Missense	distal	-5	no	8.513	8.464	EPSD	TCGA;COSMIC	2.642	Down-regulation
CMGC_CDK_CDK4_CDK4_ST	Q8IZL8	PELP1	P11802	CDK4	T1082	Q1077H	1077	Missense	distal	-5	no	6.998	6.979	EPSD	TCGA	2.642	Down-regulation
CMGC_CDK_CDK4_CDK4_ST	Q8IZL8	PELP1	P11802	CDK4	T1082	P1083L	1083	Missense	proximal	1	no	6.998	-0.581	EPSD	TCGA;COSMIC	2.642	Loss
CMGC_CDK_CDK4_CDK4_ST	P06400	RB1	P11802	CDK4	S230	F226L	226	Missense	distal	-4	no	7.809	7.810	EPSD	TCGA;ICGC;COSMIC	2.642	Up-regulation
CMGC_CDK_CDK4_CDK4_ST	P06400	RB1	P11802	CDK4	S230	Y225C	225	Missense	distal	-5	no	7.809	7.772	EPSD	TCGA;ICGC	2.642	Down-regulation
CMGC_CDK_CDK4_CDK4_ST	P06400	RB1	P11802	CDK4	S249	R255Q	255	Missense	distal	6	no	8.504	8.456	EPSD	TCGA;ICGC;COSMIC	2.642	Down-regulation
CMGC_CDK_CDK4_CDK4_ST	P06400	RB1	P11802	CDK4	S249	R251Q	251	Missense	proximal	2	no	8.504	8.396	EPSD	TCGA;ICGC;COSMIC;CCLE	2.642	Down-regulation
CMGC_CDK_CDK4_CDK4_ST	P06400	RB1	P11802	CDK4	T252	R255Q	255	Missense	distal	3	no	8.096	7.747	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	2.642	Down-regulation
CMGC_CDK_CDK4_CDK4_ST	P06400	RB1	P11802	CDK4	T252	R251Q	251	Missense	proximal	-1	no	8.096	8.200	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC;CCLE	2.642	Up-regulation
CMGC_CDK_CDK4_CDK4_ST	P06400	RB1	P11802	CDK4	T252	P245A	245	Missense	distal	-7	no	8.096	8.080	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	2.642	Down-regulation
CMGC_CDK_CDK4_CDK4_ST	P06400	RB1	P11802	CDK4	T252	R259S	259	Missense	distal	7	no	8.096	8.110	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	2.642	Up-regulation
CMGC_CDK_CDK4_CDK4_ST	P06400	RB1	P11802	CDK4	T356	S350I	350	Missense	distal	-6	no	7.068	7.435	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC;GDSC	2.642	Up-regulation
CMGC_CDK_CDK4_CDK4_ST	P06400	RB1	P11802	CDK4	T373	P374A	374	Missense	proximal	1	no	7.816	0.878	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	2.642	Loss
CMGC_CDK_CDK4_CDK4_ST	P06400	RB1	P11802	CDK4	T373	M379L	379	Missense	distal	6	no	7.816	7.823	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	2.642	Up-regulation
CMGC_CDK_CDK4_CDK4_ST	P06400	RB1	P11802	CDK4	S567	S567L	567	Missense	central	0	yes	8.961	0.000	EPSD	TCGA;ICGC;COSMIC	2.642	Loss
CMGC_CDK_CDK4_CDK4_ST	P06400	RB1	P11802	CDK4	S567	W563S	563	Missense	distal	-4	no	8.961	8.960	EPSD	TCGA;ICGC;COSMIC	2.642	Down-regulation
CMGC_CDK_CDK4_CDK4_ST	P06400	RB1	P11802	CDK4	S567	A562E	562	Missense	distal	-5	no	8.961	8.918	EPSD	TCGA;ICGC;COSMIC	2.642	Down-regulation
CMGC_CDK_CDK4_CDK4_ST	P06400	RB1	P11802	CDK4	S608	D604G	604	Missense	distal	-4	no	8.292	8.293	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	2.642	Up-regulation
CMGC_CDK_CDK4_CDK4_ST	P06400	RB1	P11802	CDK4	S780	I782M	782	Missense	proximal	2	no	8.334	8.360	PhosphoSitePlus;EPSD	TCGA;ICGC;COSMIC	2.642	Up-regulation
CMGC_CDK_CDK4_CDK4_ST	P06400	RB1	P11802	CDK4	S780	R787Q	787	Missense	distal	7	no	8.334	8.329	PhosphoSitePlus;EPSD	TCGA;ICGC;COSMIC	2.642	Down-regulation
CMGC_CDK_CDK4_CDK4_ST	P06400	RB1	P11802	CDK4	S788	I782M	782	Missense	distal	-6	no	9.839	9.792	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	2.642	Down-regulation
CMGC_CDK_CDK4_CDK4_ST	P06400	RB1	P11802	CDK4	S788	S788N	788	Missense	central	0	yes	9.839	0.000	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	2.642	Loss
CMGC_CDK_CDK4_CDK4_ST	P06400	RB1	P11802	CDK4	S788	R787Q	787	Missense	proximal	-1	no	9.839	9.944	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	2.642	Up-regulation
CMGC_CDK_CDK4_CDK4_ST	P06400	RB1	P11802	CDK4	S795	S788N	788	Missense	distal	-7	no	8.275	7.807	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	2.642	Down-regulation
CMGC_CDK_CDK4_CDK4_ST	P06400	RB1	P11802	CDK4	S795	R798W	798	Missense	distal	3	no	8.275	7.785	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC;GDSC	2.642	Down-regulation
CMGC_CDK_CDK4_CDK4_ST	P06400	RB1	P11802	CDK4	S807	N803S	803	Missense	distal	-4	no	8.321	8.320	EPSD;PhosphoSitePlus	TCGA;ICGC	2.642	Down-regulation
CMGC_CDK_CDK4_CDK4_ST	P06400	RB1	P11802	CDK4	T821	P827S	827	Missense	distal	6	no	6.539	6.697	EPSD	TCGA;ICGC;COSMIC	2.642	Up-regulation
CMGC_CDK_CDK4_CDK4_ST	P06400	RB1	P11802	CDK4	T823	P827S	827	Missense	distal	4	no	2.643	2.437	EPSD	TCGA;ICGC;COSMIC	2.642	Loss
CMGC_CDK_CDK4_CDK4_ST	P06400	RB1	P11802	CDK4	T826	P827S	827	Missense	proximal	1	no	9.039	2.852	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	2.642	Down-regulation
CMGC_CDK_CDK4_CDK4_ST	Q08999	RBL2	P11802	CDK4	S8	P13L	13	Missense	distal	5	no	7.843	7.894	EPSD	TCGA;ICGC;COSMIC	2.642	Up-regulation
CMGC_CDK_CDK4_CDK4_ST	Q08999	RBL2	P11802	CDK4	S413	S420F	420	Missense	distal	7	no	7.836	7.811	EPSD	TCGA;COSMIC	2.642	Down-regulation
CMGC_CDK_CDK4_CDK4_ST	Q08999	RBL2	P11802	CDK4	T417	S420F	420	Missense	distal	3	no	7.203	6.612	EPSD	TCGA;COSMIC	2.642	Down-regulation
CMGC_CDK_CDK4_CDK4_ST	Q08999	RBL2	P11802	CDK4	T434	R428C	428	Missense	distal	-6	no	2.606	2.711	EPSD	TCGA;COSMIC	2.642	Gain
CMGC_CDK_CDK4_CDK4_ST	Q08999	RBL2	P11802	CDK4	S603	E607K	607	Missense	distal	4	no	8.467	8.417	EPSD	TCGA;COSMIC	2.642	Down-regulation
CMGC_CDK_CDK4_CDK4_ST	Q08999	RBL2	P11802	CDK4	S603	P604S	604	Missense	proximal	1	no	8.467	2.280	EPSD	TCGA	2.642	Loss
CMGC_CDK_CDK4_CDK4_ST	Q08999	RBL2	P11802	CDK4	S603	P604A	604	Missense	proximal	1	no	8.467	1.529	EPSD	TCGA;COSMIC	2.642	Loss
CMGC_CDK_CDK4_CDK4_ST	Q08999	RBL2	P11802	CDK4	S662	P663A	663	Missense	proximal	1	no	7.975	1.037	EPSD	TCGA;ICGC;COSMIC	2.642	Loss
CMGC_CDK_CDK4_CDK4_ST	Q08999	RBL2	P11802	CDK4	S688	D691N	691	Missense	distal	3	no	7.073	7.440	EPSD	TCGA;ICGC;COSMIC	2.642	Up-regulation
CMGC_CDK_CDK4_CDK4_ST	Q08999	RBL2	P11802	CDK4	T694	D691N	691	Missense	distal	-3	no	6.552	6.476	EPSD	TCGA;ICGC;COSMIC	2.642	Down-regulation
CMGC_CDK_CDK4_CDK4_ST	Q08999	RBL2	P11802	CDK4	T694	R697L	697	Missense	distal	3	no	6.552	6.200	EPSD	TCGA;ICGC;COSMIC	2.642	Down-regulation
CMGC_CDK_CDK4_CDK4_ST	Q08999	RBL2	P11802	CDK4	S966	V968F	968	Missense	proximal	2	no	8.353	8.328	EPSD	TCGA;ICGC;COSMIC	2.642	Down-regulation
CMGC_CDK_CDK4_CDK4_ST	Q08999	RBL2	P11802	CDK4	S966	R960G	960	Missense	distal	-6	no	8.353	8.630	EPSD	TCGA;ICGC;COSMIC	2.642	Up-regulation
CMGC_CDK_CDK4_CDK4_ST	Q08999	RBL2	P11802	CDK4	S966	M969T	969	Missense	distal	3	no	8.353	8.522	EPSD	TCGA;ICGC	2.642	Up-regulation
CMGC_CDK_CDK4_CDK4_ST	Q08999	RBL2	P11802	CDK4	S973	V968F	968	Missense	distal	-5	no	2.783	2.759	EPSD	TCGA;ICGC;COSMIC	2.642	Down-regulation
CMGC_CDK_CDK4_CDK4_ST	Q08999	RBL2	P11802	CDK4	T986	R989H	989	Missense	distal	3	no	7.562	7.195	EPSD	TCGA;ICGC;COSMIC	2.642	Down-regulation
CMGC_CDK_CDK4_CDK4_ST	Q08999	RBL2	P11802	CDK4	T986	P987H	987	Missense	proximal	1	no	7.562	0.979	EPSD	TCGA;ICGC	2.642	Loss
CMGC_CDK_CDK4_CDK4_ST	Q08999	RBL2	P11802	CDK4	T986	G992V	992	Missense	distal	6	no	7.562	7.660	EPSD	TCGA;ICGC;COSMIC	2.642	Up-regulation
CMGC_CDK_CDK4_CDK4_ST	Q08999	RBL2	P11802	CDK4	S1035	P1032L	1032	Missense	distal	-3	no	8.592	8.849	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	2.642	Up-regulation
CMGC_CDK_CDK4_CDK4_ST	Q08999	RBL2	P11802	CDK4	S1035	P1033T	1033	Missense	proximal	-2	no	8.592	8.170	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	2.642	Down-regulation
CMGC_CDK_CDK4_CDK4_ST	Q08999	RBL2	P11802	CDK4	T1042	G1043S	1043	Missense	proximal	1	no	2.898	2.512	EPSD	TCGA	2.642	Loss
CMGC_CDK_CDK4_CDK4_ST	Q08999	RBL2	P11802	CDK4	S1044	G1043S	1043	Missense	proximal	-1	no	8.959	8.443	EPSD	TCGA	2.642	Down-regulation
CMGC_CDK_CDK4_CDK4_ST	Q08999	RBL2	P11802	CDK4	S1059	P1055H	1055	Missense	distal	-4	no	6.427	6.428	EPSD	TCGA	2.642	Up-regulation
CMGC_CDK_CDK4_CDK4_ST	Q08999	RBL2	P11802	CDK4	S1068	R1070Q	1070	Missense	proximal	2	no	6.398	6.290	EPSD	TCGA;COSMIC	2.642	Down-regulation
CMGC_CDK_CDK4_CDK4_ST	Q08999	RBL2	P11802	CDK4	S1068	K1072T	1072	Missense	distal	4	no	6.398	6.449	EPSD	TCGA;COSMIC	2.642	Up-regulation
CMGC_CDK_CDK4_CDK4_ST	Q08999	RBL2	P11802	CDK4	S1068	K1072N	1072	Missense	distal	4	no	6.398	6.448	EPSD	TCGA	2.642	Up-regulation
CMGC_CDK_CDK4_CDK4_ST	Q08999	RBL2	P11802	CDK4	S1080	K1083Q	1083	Missense	distal	3	no	7.198	6.841	EPSD	TCGA	2.642	Down-regulation
CMGC_CDK_CDK4_CDK4_ST	Q08999	RBL2	P11802	CDK4	T1097	R1102T	1102	Missense	distal	5	no	7.515	7.514	EPSD	TCGA;COSMIC	2.642	Down-regulation
CMGC_CDK_CDK4_CDK4_ST	Q08999	RBL2	P11802	CDK4	S1112	R1116T	1116	Missense	distal	4	no	8.786	8.782	EPSD	TCGA;COSMIC	2.642	Down-regulation
CMGC_CDK_CDK4_CDK4_ST	Q08999	RBL2	P11802	CDK4	S1112	S1110N	1110	Missense	proximal	-2	no	8.786	8.657	EPSD	TCGA;COSMIC	2.642	Down-regulation
CMGC_CDK_CDK4_CDK4_ST	Q08999	RBL2	P11802	CDK4	S1112	L1105I	1105	Missense	distal	-7	no	8.786	8.821	EPSD	TCGA;COSMIC	2.642	Up-regulation
CMGC_CDK_CDK4_CDK4_ST	Q08050	FOXM1	P11802	CDK4	S704	S704N	704	Missense	central	0	yes	9.031	0.000	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	2.642	Loss
CMGC_CDK_CDK4_CDK4_ST	P30304	CDC25A	P11802	CDK4	S76	S69T	69	Missense	distal	-7	no	3.342	2.932	EPSD	TCGA;ICGC;COSMIC	2.642	Down-regulation
CMGC_CDK_CDK4_CDK4_ST	P30304	CDC25A	P11802	CDK4	S76	R73K	73	Missense	distal	-3	no	3.342	3.321	EPSD	TCGA;ICGC;COSMIC	2.642	Down-regulation
CMGC_CDK_CDK4_CDK4_ST	P30304	CDC25A	P11802	CDK4	S76	N70S	70	Missense	distal	-6	no	3.342	3.130	EPSD	TCGA;ICGC;COSMIC	2.642	Down-regulation
CMGC_CDK_CDK4_CDK4_ST	P30304	CDC25A	P11802	CDK4	S76	E78K	78	Missense	proximal	2	no	3.342	3.427	EPSD	TCGA;ICGC;COSMIC	2.642	Up-regulation
CMGC_CDK_CDK4_CDK4_ST	P30304	CDC25A	P11802	CDK4	S88	D87Y	87	Missense	proximal	-1	no	7.444	7.367	EPSD	TCGA;ICGC;COSMIC	2.642	Down-regulation
CMGC_CDK_CDK4_CDK4_ST	P30304	CDC25A	P11802	CDK4	S88	P89L	89	Missense	proximal	1	no	7.444	-0.135	EPSD	TCGA;ICGC;COSMIC	2.642	Loss
CMGC_CDK_CDK4_CDK4_ST	P30304	CDC25A	P11802	CDK4	S88	P91S	91	Missense	distal	3	no	7.444	7.139	EPSD	TCGA;ICGC	2.642	Down-regulation
CMGC_CDK_CDK4_CDK4_ST	P30304	CDC25A	P11802	CDK4	S116	R121S	121	Missense	distal	5	no	8.452	8.429	EPSD	TCGA;ICGC;COSMIC	2.642	Down-regulation
CMGC_CDK_CDK4_CDK4_ST	P30304	CDC25A	P11802	CDK4	S116	L119V	119	Missense	distal	3	no	8.452	8.294	EPSD	TCGA;ICGC;COSMIC	2.642	Down-regulation
CMGC_CDK_CDK4_CDK4_ST	P30304	CDC25A	P11802	CDK4	S116	P117S	117	Missense	proximal	1	no	8.452	2.265	EPSD	TCGA;ICGC;COSMIC	2.642	Loss
CMGC_CDK_CDK4_CDK4_ST	P30304	CDC25A	P11802	CDK4	S116	L113F	113	Missense	distal	-3	no	8.452	8.417	EPSD	TCGA;ICGC;COSMIC	2.642	Down-regulation
CMGC_CDK_CDK4_CDK4_ST	P30304	CDC25A	P11802	CDK4	S261	N254Y	254	Missense	distal	-7	no	8.023	7.895	EPSD	TCGA;ICGC;COSMIC	2.642	Down-regulation
CMGC_CDK_CDK4_CDK4_ST	P30304	CDC25A	P11802	CDK4	S283	P284T	284	Missense	proximal	1	no	7.257	0.730	EPSD	TCGA;ICGC;COSMIC	2.642	Loss
CMGC_CDK_CDK4_CDK4_ST	P30304	CDC25A	P11802	CDK4	S298	S298N	298	Missense	central	0	yes	7.647	0.000	EPSD	TCGA;ICGC;COSMIC	2.642	Loss
CMGC_CDK_CDK4_CDK4_ST	P30304	CDC25A	P11802	CDK4	S321	S317F	317	Missense	distal	-4	no	6.140	6.141	EPSD	TCGA;ICGC;COSMIC	2.642	Up-regulation
CMGC_CDK_CDK4_CDK4_ST	P30304	CDC25A	P11802	CDK4	S361	S367C	367	Missense	distal	6	no	7.424	7.208	EPSD	TCGA;ICGC;COSMIC	2.642	Down-regulation
CMGC_CDK_CDK4_CDK4_ST	P30304	CDC25A	P11802	CDK4	S361	P362L	362	Missense	proximal	1	no	7.424	-0.155	EPSD	TCGA;ICGC;COSMIC	2.642	Loss
CMGC_CDK_CDK4_CDK4_ST	P30304	CDC25A	P11802	CDK4	S361	A366T	366	Missense	distal	5	no	7.424	7.432	EPSD	TCGA;ICGC;COSMIC	2.642	Up-regulation
CMGC_CDK_CDK4_CDK4_ST	P30304	CDC25A	P11802	CDK4	S361	Q355P	355	Missense	distal	-6	no	7.424	7.359	EPSD	TCGA;ICGC;COSMIC	2.642	Down-regulation
CMGC_CDK_CDK4_CDK4_ST	Q12778	FOXO1	P11802	CDK4	T231	R225C	225	Missense	distal	-6	no	2.670	2.776	EPSD	TCGA;ICGC;COSMIC	2.642	Up-regulation
CMGC_CDK_CDK4_CDK4_ST	Q12778	FOXO1	P11802	CDK4	T231	R225H	225	Missense	distal	-6	no	2.670	2.715	EPSD	TCGA;ICGC;COSMIC;GDSC;CCLE	2.642	Up-regulation
CMGC_CDK_CDK4_CDK4_ST	Q12778	FOXO1	P11802	CDK4	S249	A255T	255	Missense	distal	6	no	8.300	8.256	PhosphoSitePlus	TCGA;ICGC;COSMIC	2.642	Down-regulation
CMGC_CDK_CDK4_CDK4_ST	Q12778	FOXO1	P11802	CDK4	S249	R251S	251	Missense	proximal	2	no	8.300	8.421	PhosphoSitePlus	TCGA;ICGC;COSMIC	2.642	Up-regulation
CMGC_CDK_CDK4_CDK4_ST	Q12778	FOXO1	P11802	CDK4	S249	P250L	250	Missense	proximal	1	no	8.300	0.720	PhosphoSitePlus	TCGA;ICGC;COSMIC	2.642	Loss
CMGC_CDK_CDK4_CDK4_ST	Q12778	FOXO1	P11802	CDK4	S249	P250S	250	Missense	proximal	1	no	8.300	2.113	PhosphoSitePlus	TCGA;ICGC;COSMIC	2.642	Loss
CMGC_CDK_CDK4_CDK4_ST	Q12778	FOXO1	P11802	CDK4	S249	S249Y	249	Missense	central	0	yes	8.300	0.000	PhosphoSitePlus	TCGA;ICGC;COSMIC	2.642	Loss
CMGC_CDK_CDK4_CDK4_ST	Q12778	FOXO1	P11802	CDK4	S279	S279F	279	Missense	central	0	yes	3.246	0.000	EPSD	TCGA;ICGC;COSMIC	2.642	Loss
CMGC_CDK_CDK4_CDK4_ST	Q12778	FOXO1	P11802	CDK4	S287	G289E	289	Missense	proximal	2	no	6.464	6.708	EPSD	TCGA;ICGC;COSMIC	2.642	Up-regulation
CMGC_CDK_CDK4_CDK4_ST	Q12778	FOXO1	P11802	CDK4	S298	P299S	299	Missense	proximal	1	no	7.696	1.509	EPSD	TCGA;ICGC;COSMIC	2.642	Loss
CMGC_CDK_CDK4_CDK4_ST	Q12778	FOXO1	P11802	CDK4	S301	P299S	299	Missense	proximal	-2	no	3.471	3.166	EPSD	TCGA;ICGC;COSMIC	2.642	Down-regulation
CMGC_CDK_CDK4_CDK4_ST	Q12778	FOXO1	P11802	CDK4	T312	R314C	314	Missense	proximal	2	no	2.680	2.506	EPSD	TCGA;ICGC;COSMIC	2.642	Loss
CMGC_CDK_CDK4_CDK4_ST	Q12778	FOXO1	P11802	CDK4	T312	W310L	310	Missense	proximal	-2	no	2.680	2.650	EPSD	TCGA;ICGC;COSMIC	2.642	Down-regulation
CMGC_CDK_CDK4_CDK4_ST	Q12778	FOXO1	P11802	CDK4	T312	R314H	314	Missense	proximal	2	no	2.680	2.554	EPSD	TCGA;ICGC;COSMIC	2.642	Loss
CMGC_CDK_CDK4_CDK4_ST	Q12778	FOXO1	P11802	CDK4	T312	F313V	313	Missense	proximal	1	no	2.680	1.016	EPSD	TCGA;ICGC	2.642	Loss
CMGC_CDK_CDK4_CDK4_ST	Q12778	FOXO1	P11802	CDK4	T312	R316Q	316	Missense	distal	4	no	2.680	2.747	EPSD	TCGA;ICGC;COSMIC	2.642	Up-regulation
CMGC_CDK_CDK4_CDK4_ST	Q12778	FOXO1	P11802	CDK4	S318	T323A	323	Missense	distal	5	no	3.323	3.315	EPSD	TCGA;ICGC;COSMIC	2.642	Down-regulation
CMGC_CDK_CDK4_CDK4_ST	Q12778	FOXO1	P11802	CDK4	S318	F313V	313	Missense	distal	-5	no	3.323	3.347	EPSD	TCGA;ICGC	2.642	Up-regulation
CMGC_CDK_CDK4_CDK4_ST	Q12778	FOXO1	P11802	CDK4	S318	R316Q	316	Missense	proximal	-2	no	3.323	3.264	EPSD	TCGA;ICGC;COSMIC	2.642	Down-regulation
CMGC_CDK_CDK4_CDK4_ST	Q12778	FOXO1	P11802	CDK4	S329	M332I	332	Missense	distal	3	no	8.621	8.460	EPSD	TCGA;COSMIC	2.642	Down-regulation
CMGC_CDK_CDK4_CDK4_ST	Q12778	FOXO1	P11802	CDK4	S329	G326R	326	Missense	distal	-3	no	8.621	8.503	EPSD	TCGA;ICGC;COSMIC	2.642	Down-regulation
CMGC_CDK_CDK4_CDK4_ST	Q12778	FOXO1	P11802	CDK4	S329	S329L	329	Missense	central	0	yes	8.621	0.000	EPSD	TCGA;ICGC;COSMIC	2.642	Loss
CMGC_CDK_CDK4_CDK4_ST	Q12778	FOXO1	P11802	CDK4	S329	T323A	323	Missense	distal	-6	no	8.621	8.533	EPSD	TCGA;ICGC;COSMIC	2.642	Down-regulation
CMGC_CDK_CDK4_CDK4_ST	Q12778	FOXO1	P11802	CDK4	S383	L387I	387	Missense	distal	4	no	7.429	7.451	EPSD	TCGA;ICGC;COSMIC	2.642	Up-regulation
CMGC_CDK_CDK4_CDK4_ST	Q12778	FOXO1	P11802	CDK4	S383	L378I	378	Missense	distal	-5	no	7.429	7.444	EPSD	TCGA;ICGC	2.642	Up-regulation
CMGC_CDK_CDK4_CDK4_ST	Q12778	FOXO1	P11802	CDK4	S394	L387I	387	Missense	distal	-7	no	5.987	6.022	EPSD	TCGA;ICGC;COSMIC	2.642	Up-regulation
CMGC_CDK_CDK4_CDK4_ST	Q12778	FOXO1	P11802	CDK4	T402	S406L	406	Missense	distal	4	no	6.520	6.888	EPSD	TCGA;ICGC;COSMIC	2.642	Up-regulation
CMGC_CDK_CDK4_CDK4_ST	Q12778	FOXO1	P11802	CDK4	T402	A408V	408	Missense	distal	6	no	6.520	6.400	EPSD	TCGA;ICGC;COSMIC	2.642	Down-regulation
CMGC_CDK_CDK4_CDK4_ST	Q12778	FOXO1	P11802	CDK4	T402	T402M	402	Missense	central	0	yes	6.520	0.000	EPSD	TCGA;ICGC;COSMIC	2.642	Loss
CMGC_CDK_CDK4_CDK4_ST	Q12778	FOXO1	P11802	CDK4	T402	A408T	408	Missense	distal	6	no	6.520	6.476	EPSD	TCGA;ICGC;COSMIC	2.642	Down-regulation
CMGC_CDK_CDK4_CDK4_ST	Q12778	FOXO1	P11802	CDK4	S416	L414S	414	Missense	proximal	-2	no	7.267	7.490	EPSD	TCGA;ICGC;COSMIC	2.642	Up-regulation
CMGC_CDK_CDK4_CDK4_ST	Q12778	FOXO1	P11802	CDK4	S418	L414S	414	Missense	distal	-4	no	8.469	8.467	EPSD	TCGA;ICGC;COSMIC	2.642	Down-regulation
CMGC_CDK_CDK4_CDK4_ST	P84022	SMAD3	P11802	CDK4	T8	P9S	9	Missense	proximal	1	no	7.461	1.274	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	2.642	Loss
CMGC_CDK_CDK4_CDK4_ST	P84022	SMAD3	P11802	CDK4	T132	L135V	135	Missense	distal	3	no	5.784	5.626	EPSD	TCGA;ICGC;COSMIC	2.642	Down-regulation
CMGC_CDK_CDK4_CDK4_ST	P84022	SMAD3	P11802	CDK4	T132	Q128H	128	Missense	distal	-4	no	5.784	5.785	EPSD	TCGA;ICGC;COSMIC	2.642	Up-regulation
CMGC_CDK_CDK4_CDK4_ST	P84022	SMAD3	P11802	CDK4	T179	E178D	178	Missense	proximal	-1	no	8.331	8.464	EPSD;PhosphoSitePlus	TCGA;COSMIC	2.642	Up-regulation
CMGC_CDK_CDK4_CDK4_ST	P84022	SMAD3	P11802	CDK4	S204	S204Y	204	Missense	central	0	yes	7.126	0.000	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	2.642	Loss
CMGC_CDK_CDK4_CDK4_ST	P84022	SMAD3	P11802	CDK4	S204	S199N	199	Missense	distal	-5	no	7.126	7.033	EPSD;PhosphoSitePlus	TCGA	2.642	Down-regulation
CMGC_CDK_CDK4_CDK4_ST	P84022	SMAD3	P11802	CDK4	S208	S204Y	204	Missense	distal	-4	no	7.256	7.257	PhosphoSitePlus;EPSD	TCGA;ICGC;COSMIC	2.642	Up-regulation
CMGC_CDK_CDK4_CDK4_ST	P84022	SMAD3	P11802	CDK4	S416	S416F	416	Missense	central	0	yes	8.706	0.000	EPSD	TCGA;ICGC;COSMIC	2.642	Loss
CMGC_CDK_CDK4_CDK4_ST	P84022	SMAD3	P11802	CDK4	S416	S418I	418	Missense	proximal	2	no	8.706	8.430	EPSD	TCGA;COSMIC	2.642	Down-regulation
CMGC_CDK_CDK4_CDK4_ST	P84022	SMAD3	P11802	CDK4	S416	R420H	420	Missense	distal	4	no	8.706	8.825	EPSD	TCGA;ICGC;COSMIC	2.642	Up-regulation
CMGC_CDK_CDK4_CDK4_ST	P84022	SMAD3	P11802	CDK4	S416	S423R	423	Missense	distal	7	no	8.706	8.691	EPSD	TCGA;ICGC;COSMIC	2.642	Down-regulation
CMGC_CDK_CDK4_CDK4_ST	P84022	SMAD3	P11802	CDK4	S416	P417L	417	Missense	proximal	1	no	8.706	1.127	EPSD	TCGA;ICGC;COSMIC	2.642	Loss
CMGC_CDK_CDK4_CDK4_ST	P84022	SMAD3	P11802	CDK4	S416	S418N	418	Missense	proximal	2	no	8.706	8.522	EPSD	TCGA;ICGC;COSMIC	2.642	Down-regulation
CMGC_CDK_CDK4_CDK4_ST	P26358	DNMT1	P11802	CDK4	S127	D124H	124	Missense	distal	-3	no	7.446	7.417	PhosphoSitePlus;EPSD	TCGA;ICGC;COSMIC	2.642	Down-regulation
CMGC_CDK_CDK4_CDK4_ST	P26358	DNMT1	P11802	CDK4	S714	M712I	712	Missense	proximal	-2	no	7.377	7.320	EPSD	TCGA;ICGC;COSMIC	2.642	Down-regulation
CMGC_CDK_CDK4_CDK4_ST	Q14814	MEF2D	P11802	CDK4	S98	G95V	95	Missense	distal	-3	no	8.576	8.529	PhosphoSitePlus;EPSD	TCGA;ICGC;COSMIC	2.642	Down-regulation
CMGC_CDK_CDK4_CDK4_ST	Q14814	MEF2D	P11802	CDK4	S98	C96Y	96	Missense	proximal	-2	no	8.576	8.626	PhosphoSitePlus;EPSD	TCGA;ICGC;COSMIC	2.642	Up-regulation
CMGC_CDK_CDK4_CDK4_ST	Q14814	MEF2D	P11802	CDK4	S98	E100K	100	Missense	proximal	2	no	8.576	8.661	PhosphoSitePlus;EPSD	TCGA;ICGC	2.642	Up-regulation
CMGC_CDK_CDK4_CDK4_ST	Q14814	MEF2D	P11802	CDK4	S98	G92D	92	Missense	distal	-6	no	8.576	8.363	PhosphoSitePlus;EPSD	TCGA;ICGC;COSMIC	2.642	Down-regulation
CMGC_CDK_CDK4_CDK4_ST	Q14814	MEF2D	P11802	CDK4	S110	P111R	111	Missense	proximal	1	no	7.937	1.150	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	2.642	Loss
CMGC_CDK_CDK4_CDK4_ST	Q14814	MEF2D	P11802	CDK4	S110	P111S	111	Missense	proximal	1	no	7.937	1.750	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	2.642	Loss
CMGC_CDK_CDK4_CDK4_ST	Q14814	MEF2D	P11802	CDK4	S180	L179M	179	Missense	proximal	-1	no	7.159	7.160	EPSD	TCGA;COSMIC	2.642	Up-regulation
CMGC_CDK_CDK4_CDK4_ST	Q14814	MEF2D	P11802	CDK4	S190	G194V	194	Missense	distal	4	no	2.789	2.611	EPSD	TCGA;COSMIC	2.642	Loss
CMGC_CDK_CDK4_CDK4_ST	Q14814	MEF2D	P11802	CDK4	S192	G194V	194	Missense	proximal	2	no	8.333	8.491	EPSD	TCGA;COSMIC	2.642	Up-regulation
CMGC_CDK_CDK4_CDK4_ST	Q14814	MEF2D	P11802	CDK4	S219	C217Y	217	Missense	proximal	-2	no	6.601	6.651	EPSD	TCGA	2.642	Up-regulation
CMGC_CDK_CDK4_CDK4_ST	Q14814	MEF2D	P11802	CDK4	S219	N223D	223	Missense	distal	4	no	6.601	6.767	EPSD	TCGA	2.642	Up-regulation
CMGC_CDK_CDK4_CDK4_ST	Q14814	MEF2D	P11802	CDK4	S231	S227G	227	Missense	distal	-4	no	7.055	7.057	EPSD	TCGA;COSMIC	2.642	Up-regulation
CMGC_CDK_CDK4_CDK4_ST	Q14814	MEF2D	P11802	CDK4	S231	R229Q	229	Missense	proximal	-2	no	7.055	6.996	EPSD	TCGA;COSMIC	2.642	Down-regulation
CMGC_CDK_CDK4_CDK4_ST	Q14814	MEF2D	P11802	CDK4	S251	P252A	252	Missense	proximal	1	no	8.081	1.144	EPSD	TCGA;COSMIC	2.642	Loss
CMGC_CDK_CDK4_CDK4_ST	Q14814	MEF2D	P11802	CDK4	S251	P255S	255	Missense	distal	4	no	8.081	7.875	EPSD	TCGA;COSMIC	2.642	Down-regulation
CMGC_CDK_CDK4_CDK4_ST	Q14814	MEF2D	P11802	CDK4	S251	P252L	252	Missense	proximal	1	no	8.081	0.502	EPSD	TCGA;COSMIC	2.642	Loss
CMGC_CDK_CDK4_CDK4_ST	Q14814	MEF2D	P11802	CDK4	S444	S437N	437	Missense	distal	-7	no	10.359	9.891	EPSD	TCGA;COSMIC	2.642	Down-regulation
CMGC_CDK_CDK4_CDK4_ST	Q14814	MEF2D	P11802	CDK4	S444	P445S	445	Missense	proximal	1	no	10.359	4.172	EPSD	TCGA;COSMIC	2.642	Down-regulation
CMGC_CDK_CDK4_CDK4_ST	Q14814	MEF2D	P11802	CDK4	S450	P445S	445	Missense	distal	-5	no	7.572	7.709	EPSD	TCGA;COSMIC	2.642	Up-regulation
CMGC_CDK_CDK4_CDK4_ST	Q14814	MEF2D	P11802	CDK4	S450	P456S	456	Missense	distal	6	no	7.572	7.730	EPSD	TCGA;COSMIC	2.642	Up-regulation
CMGC_CDK_CDK4_CDK4_ST	Q14814	MEF2D	P11802	CDK4	S450	P455S	455	Missense	distal	5	no	7.572	7.586	EPSD	TCGA;COSMIC	2.642	Up-regulation
CMGC_CDK_CDK4_CDK4_ST	Q14814	MEF2D	P11802	CDK4	S450	P455A	455	Missense	distal	5	no	7.572	7.600	EPSD	TCGA;COSMIC	2.642	Up-regulation
CMGC_CDK_CDK4_CDK4_ST	Q14814	MEF2D	P11802	CDK4	S472	P473L	473	Missense	proximal	1	no	8.018	0.439	EPSD	TCGA;COSMIC	2.642	Loss
CMGC_CDK_CDK4_CDK4_ST	Q14814	MEF2D	P11802	CDK4	S472	A474V	474	Missense	proximal	2	no	8.018	7.841	EPSD	TCGA;COSMIC	2.642	Down-regulation
CMGC_CDK_CDK4_CDK4_ST	Q14814	MEF2D	P11802	CDK4	S472	Y478H	478	Missense	distal	6	no	8.018	8.001	EPSD	TCGA;COSMIC	2.642	Down-regulation
CMGC_CDK_CDK4_CDK4_ST	Q14814	MEF2D	P11802	CDK4	S472	G476E	476	Missense	distal	4	no	8.018	7.677	EPSD	TCGA;COSMIC	2.642	Down-regulation
CMGC_CDK_CDK4_CDK4_ST	P38398	BRCA1	P11802	CDK4	S114	N113K	113	Missense	proximal	-1	no	6.552	6.450	EPSD	TCGA;ICGC;COSMIC	2.642	Down-regulation
CMGC_CDK_CDK4_CDK4_ST	P38398	BRCA1	P11802	CDK4	T208	T212A	212	Missense	distal	4	no	5.791	5.656	EPSD	TCGA;ICGC	2.642	Down-regulation
CMGC_CDK_CDK4_CDK4_ST	P38398	BRCA1	P11802	CDK4	S423	E418D	418	Missense	distal	-5	no	3.261	3.212	EPSD	TCGA;COSMIC	2.642	Down-regulation
CMGC_CDK_CDK4_CDK4_ST	P38398	BRCA1	P11802	CDK4	S425	E418D	418	Missense	distal	-7	no	3.107	2.877	EPSD	TCGA;COSMIC	2.642	Down-regulation
CMGC_CDK_CDK4_CDK4_ST	P38398	BRCA1	P11802	CDK4	S510	E515Q	515	Missense	distal	5	no	3.301	3.305	EPSD	TCGA;COSMIC	2.642	Up-regulation
CMGC_CDK_CDK4_CDK4_ST	P38398	BRCA1	P11802	CDK4	S510	E515V	515	Missense	distal	5	no	3.301	3.316	EPSD	TCGA;COSMIC	2.642	Up-regulation
CMGC_CDK_CDK4_CDK4_ST	P38398	BRCA1	P11802	CDK4	S510	E515K	515	Missense	distal	5	no	3.301	3.294	EPSD	TCGA;COSMIC	2.642	Down-regulation
CMGC_CDK_CDK4_CDK4_ST	P38398	BRCA1	P11802	CDK4	S510	H513Y	513	Missense	distal	3	no	3.301	3.355	EPSD	TCGA;COSMIC	2.642	Up-regulation
CMGC_CDK_CDK4_CDK4_ST	P38398	BRCA1	P11802	CDK4	T528	V525A	525	Missense	distal	-3	no	6.179	6.067	EPSD	TCGA;COSMIC	2.642	Down-regulation
CMGC_CDK_CDK4_CDK4_ST	P38398	BRCA1	P11802	CDK4	T528	P529S	529	Missense	proximal	1	no	6.179	-0.008	EPSD	TCGA;COSMIC	2.642	Loss
CMGC_CDK_CDK4_CDK4_ST	P38398	BRCA1	P11802	CDK4	S645	S646G	646	Missense	proximal	1	no	2.758	3.144	EPSD	TCGA;COSMIC	2.642	Up-regulation
CMGC_CDK_CDK4_CDK4_ST	P38398	BRCA1	P11802	CDK4	S645	C644W	644	Missense	proximal	-1	no	2.758	2.756	EPSD	TCGA;COSMIC	2.642	Down-regulation
CMGC_CDK_CDK4_CDK4_ST	P38398	BRCA1	P11802	CDK4	S708	G707R	707	Missense	proximal	-1	no	4.112	3.741	EPSD	TCGA;COSMIC	2.642	Down-regulation
CMGC_CDK_CDK4_CDK4_ST	P38398	BRCA1	P11802	CDK4	S713	G707R	707	Missense	distal	-6	no	2.914	2.638	EPSD	TCGA;COSMIC	2.642	Loss
CMGC_CDK_CDK4_CDK4_ST	P38398	BRCA1	P11802	CDK4	S753	P747L	747	Missense	distal	-6	no	2.984	3.137	EPSD	TCGA;COSMIC	2.642	Up-regulation
CMGC_CDK_CDK4_CDK4_ST	P38398	BRCA1	P11802	CDK4	S767	E765Q	765	Missense	proximal	-2	no	2.846	2.825	EPSD	TCGA;COSMIC	2.642	Down-regulation
CMGC_CDK_CDK4_CDK4_ST	P38398	BRCA1	P11802	CDK4	S868	P871S	871	Missense	distal	3	no	2.727	2.422	EPSD	TCGA;COSMIC	2.642	Loss
CMGC_CDK_CDK4_CDK4_ST	P38398	BRCA1	P11802	CDK4	S868	S873L	873	Missense	distal	5	no	2.727	2.764	EPSD	TCGA;COSMIC	2.642	Up-regulation
CMGC_CDK_CDK4_CDK4_ST	P38398	BRCA1	P11802	CDK4	S868	P875S	875	Missense	distal	7	no	2.727	2.736	EPSD	TCGA;COSMIC	2.642	Up-regulation
CMGC_CDK_CDK4_CDK4_ST	P38398	BRCA1	P11802	CDK4	S868	R866C	866	Missense	proximal	-2	no	2.727	2.643	EPSD	TCGA;COSMIC	2.642	Down-regulation
CMGC_CDK_CDK4_CDK4_ST	P38398	BRCA1	P11802	CDK4	S896	C903S	903	Missense	distal	7	no	7.792	7.817	EPSD	TCGA;COSMIC	2.642	Up-regulation
CMGC_CDK_CDK4_CDK4_ST	P38398	BRCA1	P11802	CDK4	S896	S889C	889	Missense	distal	-7	no	7.792	7.040	EPSD	TCGA;COSMIC	2.642	Down-regulation
CMGC_CDK_CDK4_CDK4_ST	P38398	BRCA1	P11802	CDK4	S896	E902K	902	Missense	distal	6	no	7.792	7.830	EPSD	TCGA;COSMIC	2.642	Up-regulation
CMGC_CDK_CDK4_CDK4_ST	P38398	BRCA1	P11802	CDK4	S896	V899L	899	Missense	distal	3	no	7.792	7.950	EPSD	TCGA;COSMIC	2.642	Up-regulation
CMGC_CDK_CDK4_CDK4_ST	P38398	BRCA1	P11802	CDK4	S896	K893N	893	Missense	distal	-3	no	7.792	7.810	EPSD	TCGA;COSMIC	2.642	Up-regulation
CMGC_CDK_CDK4_CDK4_ST	P38398	BRCA1	P11802	CDK4	T967	E962A	962	Missense	distal	-5	no	7.182	7.224	EPSD	TCGA;COSMIC	2.642	Up-regulation
CMGC_CDK_CDK4_CDK4_ST	P38398	BRCA1	P11802	CDK4	S1009	E1013Q	1013	Missense	distal	4	no	8.180	8.251	EPSD	TCGA	2.642	Up-regulation
CMGC_CDK_CDK4_CDK4_ST	P38398	BRCA1	P11802	CDK4	S1009	N1002K	1002	Missense	distal	-7	no	8.180	8.219	EPSD	TCGA	2.642	Up-regulation
CMGC_CDK_CDK4_CDK4_ST	P38398	BRCA1	P11802	CDK4	S1021	S1027I	1027	Missense	distal	6	no	2.975	2.777	EPSD	TCGA;COSMIC	2.642	Down-regulation
CMGC_CDK_CDK4_CDK4_ST	P38398	BRCA1	P11802	CDK4	S1021	R1028C	1028	Missense	distal	7	no	2.975	2.964	EPSD	TCGA;COSMIC	2.642	Down-regulation
CMGC_CDK_CDK4_CDK4_ST	P38398	BRCA1	P11802	CDK4	S1497	G1492R	1492	Missense	distal	-5	no	9.124	9.244	EPSD	TCGA;COSMIC	2.642	Up-regulation
CMGC_CDK_CDK4_CDK4_ST	Q96KS0	EGLN2	P11802	CDK4	S74	R77Q	77	Missense	distal	3	no	7.682	7.334	EPSD	TCGA;ICGC;COSMIC	2.642	Down-regulation
CMGC_CDK_CDK4_CDK4_ST	Q96KS0	EGLN2	P11802	CDK4	S74	R77W	77	Missense	distal	3	no	7.682	7.192	EPSD	TCGA;ICGC;COSMIC	2.642	Down-regulation
CMGC_CDK_CDK4_CDK4_ST	Q96KS0	EGLN2	P11802	CDK4	S74	A68T	68	Missense	distal	-6	no	7.682	7.769	EPSD	TCGA;ICGC	2.642	Up-regulation
CMGC_CDK_CDK4_CDK4_ST	Q96KS0	EGLN2	P11802	CDK4	S130	R134Q	134	Missense	distal	4	no	6.672	6.739	PhosphoSitePlus	TCGA;ICGC;COSMIC	2.642	Up-regulation
CMGC_CDK_CDK4_CDK4_ST	Q96KS0	EGLN2	P11802	CDK4	S130	R134L	134	Missense	distal	4	no	6.672	6.808	PhosphoSitePlus	TCGA;ICGC	2.642	Up-regulation
CMGC_CDK_CDK4_CDK4_ST	Q96KS0	EGLN2	P11802	CDK4	T405	V400A	400	Missense	distal	-5	no	6.833	6.940	EPSD	TCGA;COSMIC	2.642	Up-regulation
CMGC_CDK_CDK4_CDK4_ST	P15923	TCF3	P11802	CDK4	S55	E51D	51	Missense	distal	-4	no	2.813	2.814	EPSD	TCGA	2.642	Up-regulation
CMGC_CDK_CDK4_CDK4_ST	P15923	TCF3	P11802	CDK4	S134	S134N	134	Missense	central	0	yes	9.027	0.000	EPSD	TCGA;ICGC;COSMIC	2.642	Loss
CMGC_CDK_CDK4_CDK4_ST	P15923	TCF3	P11802	CDK4	S139	S134N	134	Missense	distal	-5	no	8.524	8.430	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	2.642	Down-regulation
CMGC_CDK_CDK4_CDK4_ST	P15923	TCF3	P11802	CDK4	S141	S134N	134	Missense	distal	-7	no	4.069	3.601	EPSD	TCGA;ICGC;COSMIC	2.642	Down-regulation
CMGC_CDK_CDK4_CDK4_ST	P15923	TCF3	P11802	CDK4	S154	R160I	160	Missense	distal	6	no	5.149	5.063	EPSD	TCGA;ICGC;COSMIC	2.642	Down-regulation
CMGC_CDK_CDK4_CDK4_ST	P15923	TCF3	P11802	CDK4	S154	R159W	159	Missense	distal	5	no	5.149	5.166	EPSD	TCGA;ICGC;COSMIC	2.642	Up-regulation
CMGC_CDK_CDK4_CDK4_ST	P15923	TCF3	P11802	CDK4	S154	S157Y	157	Missense	distal	3	no	5.149	4.596	EPSD	TCGA;ICGC;COSMIC	2.642	Down-regulation
CMGC_CDK_CDK4_CDK4_ST	P15923	TCF3	P11802	CDK4	S202	P201S	201	Missense	proximal	-1	no	2.663	2.415	EPSD	TCGA;ICGC;COSMIC	2.642	Loss
CMGC_CDK_CDK4_CDK4_ST	P15923	TCF3	P11802	CDK4	S208	P201S	201	Missense	distal	-7	no	2.490	2.691	EPSD	TCGA;ICGC;COSMIC	2.642	Gain
CMGC_CDK_CDK4_CDK4_ST	P15923	TCF3	P11802	CDK4	T308	D315N	315	Missense	distal	7	no	7.602	7.612	EPSD	TCGA;ICGC;COSMIC	2.642	Up-regulation
CMGC_CDK_CDK4_CDK4_ST	P15923	TCF3	P11802	CDK4	S312	D315N	315	Missense	distal	3	no	3.102	3.469	EPSD	TCGA;ICGC;COSMIC	2.642	Up-regulation
CMGC_CDK_CDK4_CDK4_ST	P15923	TCF3	P11802	CDK4	S379	G376S	376	Missense	distal	-3	no	8.806	8.583	EPSD	TCGA;ICGC;COSMIC	2.642	Down-regulation
CMGC_CDK_CDK4_CDK4_ST	P15923	TCF3	P11802	CDK4	S529	P524S	524	Missense	distal	-5	no	8.297	8.434	EPSD	TCGA;ICGC;COSMIC	2.642	Up-regulation
CMGC_CDK_CDK4_CDK4_ST	Q9BQA1	WDR77	P11802	CDK4	T5	P8S	8	Missense	distal	3	no	8.687	8.382	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	2.642	Down-regulation
CMGC_CDK_CDK4_CDK4_ST	Q9BQA1	WDR77	P11802	CDK4	S142	D146H	146	Missense	distal	4	no	3.521	3.479	EPSD	TCGA;ICGC;COSMIC	2.642	Down-regulation
CMGC_CDK_CDK4_CDK4_ST	Q9BQA1	WDR77	P11802	CDK4	S142	V141A	141	Missense	proximal	-1	no	3.521	3.285	EPSD	TCGA;ICGC	2.642	Down-regulation
CMGC_CDK_CDK4_CDK4_ST	Q9BQA1	WDR77	P11802	CDK4	S176	S176F	176	Missense	central	0	yes	7.834	0.000	EPSD	TCGA;ICGC;COSMIC	2.642	Loss
CMGC_CDK_CDK4_CDK4_ST	Q9BQA1	WDR77	P11802	CDK4	S176	S181F	181	Missense	distal	5	no	7.834	7.866	EPSD	TCGA;ICGC;COSMIC	2.642	Up-regulation
CMGC_CDK_CDK4_CDK4_ST	Q9BQA1	WDR77	P11802	CDK4	S306	P307S	307	Missense	proximal	1	no	8.018	1.830	EPSD;PhosphoSitePlus	TCGA;COSMIC	2.642	Loss
CMGC_CDK_CDK4_CDK4_ST	Q9BQA1	WDR77	P11802	CDK4	S306	L312V	312	Missense	distal	6	no	8.018	7.999	EPSD;PhosphoSitePlus	TCGA;COSMIC	2.642	Down-regulation
CMGC_CDK_CDK4_CDK4_ST	Q9BQA1	WDR77	P11802	CDK4	S306	N309S	309	Missense	distal	3	no	8.018	8.465	EPSD;PhosphoSitePlus	TCGA;COSMIC	2.642	Up-regulation
CMGC_CDK_CDK4_CDK4_ST	Q9BQA1	WDR77	P11802	CDK4	S306	A303V	303	Missense	distal	-3	no	8.018	8.130	EPSD;PhosphoSitePlus	TCGA;COSMIC	2.642	Up-regulation
CMGC_CDK_CDK4_CDK4_ST	P55072	VCP	P11802	CDK4	S171	P172L	172	Missense	proximal	1	no	7.349	-0.231	EPSD	TCGA;ICGC;COSMIC	2.642	Loss
CMGC_CDK_CDK4_CDK4_ST	P55072	VCP	P11802	CDK4	S276	E273Q	273	Missense	distal	-3	no	3.045	3.072	EPSD	TCGA;ICGC;COSMIC	2.642	Up-regulation
CMGC_CDK_CDK4_CDK4_ST	P55072	VCP	P11802	CDK4	T509	F503V	503	Missense	distal	-6	no	8.516	8.504	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	2.642	Down-regulation
CMGC_CDK_CDK4_CDK4_ST	P55072	VCP	P11802	CDK4	S664	L657I	657	Missense	distal	-7	no	6.758	6.794	PhosphoSitePlus;EPSD	TCGA;ICGC;COSMIC	2.642	Up-regulation
CMGC_CDK_CDK4_CDK4_ST	P55072	VCP	P11802	CDK4	S664	R662C	662	Missense	proximal	-2	no	6.758	6.673	PhosphoSitePlus;EPSD	TCGA;ICGC;COSMIC	2.642	Down-regulation
CMGC_CDK_CDK4_CDK4_ST	P55072	VCP	P11802	CDK4	S683	M678I	678	Missense	distal	-5	no	3.141	3.131	EPSD	TCGA;ICGC;COSMIC	2.642	Down-regulation
CMGC_CDK_CDK4_CDK4_ST	Q92830	KAT2A	P11802	CDK4	S415	G414C	414	Missense	proximal	-1	no	3.333	3.157	EPSD	TCGA;ICGC;COSMIC	2.642	Down-regulation
CMGC_CDK_CDK4_CDK4_ST	Q92830	KAT2A	P11802	CDK4	S415	S418F	418	Missense	distal	3	no	3.333	2.742	EPSD	TCGA;ICGC;COSMIC	2.642	Down-regulation
CMGC_CDK_CDK4_CDK4_ST	Q92830	KAT2A	P11802	CDK4	S415	S410I	410	Missense	distal	-5	no	3.333	3.197	EPSD	TCGA;ICGC	2.642	Down-regulation
CMGC_CDK_CDK4_CDK4_ST	P46527	CDKN1B	P11802	CDK4	S10	S7C	7	Missense	distal	-3	no	7.994	8.167	EPSD	TCGA;ICGC;COSMIC	2.642	Up-regulation
CMGC_CDK_CDK4_CDK4_ST	P46527	CDKN1B	P11802	CDK4	S10	G9W	9	Missense	proximal	-1	no	7.994	7.815	EPSD	TCGA;ICGC;COSMIC	2.642	Down-regulation
CMGC_CDK_CDK4_CDK4_ST	P21333	FLNA	P11802	CDK4	S204	L209M	209	Missense	distal	5	no	2.917	2.914	EPSD	TCGA;ICGC;COSMIC	2.642	Down-regulation
CMGC_CDK_CDK4_CDK4_ST	P21333	FLNA	P11802	CDK4	S204	P207L	207	Missense	distal	3	no	2.917	2.018	EPSD	TCGA;ICGC;COSMIC	2.642	Loss
CMGC_CDK_CDK4_CDK4_ST	P21333	FLNA	P11802	CDK4	S368	F370Y	370	Missense	proximal	2	no	8.926	9.008	EPSD	TCGA;ICGC;COSMIC	2.642	Up-regulation
CMGC_CDK_CDK4_CDK4_ST	P21333	FLNA	P11802	CDK4	S368	E371D	371	Missense	distal	3	no	8.926	8.632	EPSD	TCGA;ICGC	2.642	Down-regulation
CMGC_CDK_CDK4_CDK4_ST	P21333	FLNA	P11802	CDK4	S368	E371K	371	Missense	distal	3	no	8.926	9.214	EPSD	TCGA;ICGC	2.642	Up-regulation
CMGC_CDK_CDK4_CDK4_ST	P21333	FLNA	P11802	CDK4	S368	A366T	366	Missense	proximal	-2	no	8.926	8.904	EPSD	TCGA;ICGC;COSMIC;CCLE	2.642	Down-regulation
CMGC_CDK_CDK4_CDK4_ST	P21333	FLNA	P11802	CDK4	S368	V372A	372	Missense	distal	4	no	8.926	8.629	EPSD	TCGA;ICGC	2.642	Down-regulation
CMGC_CDK_CDK4_CDK4_ST	P21333	FLNA	P11802	CDK4	S468	P466L	466	Missense	proximal	-2	no	8.346	7.817	EPSD	TCGA;ICGC;COSMIC	2.642	Down-regulation
CMGC_CDK_CDK4_CDK4_ST	P21333	FLNA	P11802	CDK4	S468	R467C	467	Missense	proximal	-1	no	8.346	8.541	EPSD	TCGA;ICGC;COSMIC	2.642	Up-regulation
CMGC_CDK_CDK4_CDK4_ST	P21333	FLNA	P11802	CDK4	S468	V472A	472	Missense	distal	4	no	8.346	8.049	EPSD	TCGA;ICGC	2.642	Down-regulation
CMGC_CDK_CDK4_CDK4_ST	P21333	FLNA	P11802	CDK4	S468	R467H	467	Missense	proximal	-1	no	8.346	8.495	EPSD	TCGA;ICGC	2.642	Up-regulation
CMGC_CDK_CDK4_CDK4_ST	P21333	FLNA	P11802	CDK4	S512	G509V	509	Missense	distal	-3	no	2.809	2.762	EPSD	TCGA;ICGC;COSMIC	2.642	Down-regulation
CMGC_CDK_CDK4_CDK4_ST	P21333	FLNA	P11802	CDK4	S564	E567K	567	Missense	distal	3	no	7.395	7.683	EPSD	TCGA;ICGC;COSMIC	2.642	Up-regulation
CMGC_CDK_CDK4_CDK4_ST	P21333	FLNA	P11802	CDK4	S564	G562W	562	Missense	proximal	-2	no	7.395	7.394	EPSD	TCGA;ICGC;COSMIC	2.642	Down-regulation
CMGC_CDK_CDK4_CDK4_ST	P21333	FLNA	P11802	CDK4	S564	Q559E	559	Missense	distal	-5	no	7.395	7.430	EPSD	TCGA;ICGC;COSMIC	2.642	Up-regulation
CMGC_CDK_CDK4_CDK4_ST	P21333	FLNA	P11802	CDK4	S564	P565L	565	Missense	proximal	1	no	7.395	-0.184	EPSD	TCGA;ICGC;COSMIC	2.642	Loss
CMGC_CDK_CDK4_CDK4_ST	P21333	FLNA	P11802	CDK4	S657	R655H	655	Missense	proximal	-2	no	7.746	7.710	EPSD	TCGA;ICGC;COSMIC	2.642	Down-regulation
CMGC_CDK_CDK4_CDK4_ST	P21333	FLNA	P11802	CDK4	S657	L656I	656	Missense	proximal	-1	no	7.746	7.773	EPSD	TCGA;ICGC	2.642	Up-regulation
CMGC_CDK_CDK4_CDK4_ST	P21333	FLNA	P11802	CDK4	S657	R664L	664	Missense	distal	7	no	7.746	7.735	EPSD	TCGA;ICGC;COSMIC	2.642	Down-regulation
CMGC_CDK_CDK4_CDK4_ST	P21333	FLNA	P11802	CDK4	S757	G751D	751	Missense	distal	-6	no	8.237	8.025	EPSD	TCGA;ICGC;COSMIC	2.642	Down-regulation
CMGC_CDK_CDK4_CDK4_ST	P21333	FLNA	P11802	CDK4	S757	N756K	756	Missense	proximal	-1	no	8.237	8.135	EPSD	TCGA;ICGC;COSMIC	2.642	Down-regulation
CMGC_CDK_CDK4_CDK4_ST	P21333	FLNA	P11802	CDK4	S757	S757N	757	Missense	central	0	yes	8.237	0.000	EPSD	TCGA;ICGC	2.642	Loss
CMGC_CDK_CDK4_CDK4_ST	P21333	FLNA	P11802	CDK4	S757	S753G	753	Missense	distal	-4	no	8.237	8.239	EPSD	TCGA;ICGC;COSMIC	2.642	Up-regulation
CMGC_CDK_CDK4_CDK4_ST	P21333	FLNA	P11802	CDK4	S757	N756D	756	Missense	proximal	-1	no	8.237	8.360	EPSD	TCGA;ICGC	2.642	Up-regulation
CMGC_CDK_CDK4_CDK4_ST	P21333	FLNA	P11802	CDK4	S757	G750E	750	Missense	distal	-7	no	8.237	8.766	EPSD	TCGA;ICGC	2.642	Up-regulation
CMGC_CDK_CDK4_CDK4_ST	P21333	FLNA	P11802	CDK4	S757	S753T	753	Missense	distal	-4	no	8.237	8.238	EPSD	TCGA	2.642	Up-regulation
CMGC_CDK_CDK4_CDK4_ST	P21333	FLNA	P11802	CDK4	T857	T857M	857	Missense	central	0	yes	6.955	0.000	EPSD	TCGA;COSMIC	2.642	Loss
CMGC_CDK_CDK4_CDK4_ST	P21333	FLNA	P11802	CDK4	S860	T857M	857	Missense	distal	-3	no	8.518	8.576	EPSD	TCGA;COSMIC	2.642	Up-regulation
CMGC_CDK_CDK4_CDK4_ST	P21333	FLNA	P11802	CDK4	S959	D954Y	954	Missense	distal	-5	no	8.279	8.285	EPSD	TCGA;ICGC;COSMIC	2.642	Up-regulation
CMGC_CDK_CDK4_CDK4_ST	P21333	FLNA	P11802	CDK4	S959	F961L	961	Missense	proximal	2	no	8.279	8.352	EPSD	TCGA;ICGC	2.642	Up-regulation
CMGC_CDK_CDK4_CDK4_ST	P21333	FLNA	P11802	CDK4	S966	P967S	967	Missense	proximal	1	no	9.227	3.040	EPSD	TCGA;ICGC;COSMIC	2.642	Down-regulation
CMGC_CDK_CDK4_CDK4_ST	P21333	FLNA	P11802	CDK4	S966	F961L	961	Missense	distal	-5	no	9.227	9.242	EPSD	TCGA;ICGC	2.642	Up-regulation
CMGC_CDK_CDK4_CDK4_ST	P21333	FLNA	P11802	CDK4	S1055	P1051H	1051	Missense	distal	-4	no	9.441	9.442	EPSD	TCGA;ICGC;COSMIC	2.642	Up-regulation
CMGC_CDK_CDK4_CDK4_ST	P21333	FLNA	P11802	CDK4	S1055	P1053H	1053	Missense	proximal	-2	no	9.441	8.985	EPSD	TCGA;ICGC	2.642	Down-regulation
CMGC_CDK_CDK4_CDK4_ST	P21333	FLNA	P11802	CDK4	S1084	A1082V	1082	Missense	proximal	-2	no	7.951	7.824	EPSD	TCGA;ICGC	2.642	Down-regulation
CMGC_CDK_CDK4_CDK4_ST	P21333	FLNA	P11802	CDK4	S1084	R1087H	1087	Missense	distal	3	no	7.951	7.585	EPSD	TCGA;ICGC;COSMIC	2.642	Down-regulation
CMGC_CDK_CDK4_CDK4_ST	P21333	FLNA	P11802	CDK4	S1084	R1087L	1087	Missense	distal	3	no	7.951	7.599	EPSD	TCGA;ICGC;COSMIC	2.642	Down-regulation
CMGC_CDK_CDK4_CDK4_ST	P21333	FLNA	P11802	CDK4	S1084	P1085S	1085	Missense	proximal	1	no	7.951	1.764	EPSD	TCGA;ICGC;COSMIC	2.642	Loss
CMGC_CDK_CDK4_CDK4_ST	P21333	FLNA	P11802	CDK4	S1084	D1091N	1091	Missense	distal	7	no	7.951	7.961	EPSD	TCGA;ICGC	2.642	Up-regulation
CMGC_CDK_CDK4_CDK4_ST	P21333	FLNA	P11802	CDK4	S1084	L1077P	1077	Missense	distal	-7	no	7.951	8.431	EPSD	TCGA;ICGC;COSMIC	2.642	Up-regulation
CMGC_CDK_CDK4_CDK4_ST	P21333	FLNA	P11802	CDK4	T1322	G1315D	1315	Missense	distal	-7	no	6.321	6.620	EPSD	TCGA;ICGC	2.642	Up-regulation
CMGC_CDK_CDK4_CDK4_ST	P21333	FLNA	P11802	CDK4	S1338	G1337V	1337	Missense	proximal	-1	no	7.576	7.374	EPSD	TCGA;ICGC;COSMIC	2.642	Down-regulation
CMGC_CDK_CDK4_CDK4_ST	P21333	FLNA	P11802	CDK4	S1343	G1337V	1337	Missense	distal	-6	no	7.959	7.768	EPSD	TCGA;ICGC;COSMIC	2.642	Down-regulation
CMGC_CDK_CDK4_CDK4_ST	P21333	FLNA	P11802	CDK4	S1343	Q1346H	1346	Missense	distal	3	no	7.959	7.941	EPSD	TCGA;ICGC;COSMIC	2.642	Down-regulation
CMGC_CDK_CDK4_CDK4_ST	P21333	FLNA	P11802	CDK4	S1343	F1345V	1345	Missense	proximal	2	no	7.959	7.985	EPSD	TCGA;ICGC	2.642	Up-regulation
CMGC_CDK_CDK4_CDK4_ST	P21333	FLNA	P11802	CDK4	S1436	F1438L	1438	Missense	proximal	2	no	8.728	8.802	EPSD	TCGA;ICGC;COSMIC	2.642	Up-regulation
CMGC_CDK_CDK4_CDK4_ST	P21333	FLNA	P11802	CDK4	S1459	P1456T	1456	Missense	distal	-3	no	7.700	7.874	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	2.642	Up-regulation
CMGC_CDK_CDK4_CDK4_ST	P21333	FLNA	P11802	CDK4	S1459	P1456L	1456	Missense	distal	-3	no	7.700	7.958	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	2.642	Up-regulation
CMGC_CDK_CDK4_CDK4_ST	P21333	FLNA	P11802	CDK4	S1459	V1463L	1463	Missense	distal	4	no	7.700	7.678	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	2.642	Down-regulation
CMGC_CDK_CDK4_CDK4_ST	P21333	FLNA	P11802	CDK4	S1459	S1459N	1459	Missense	central	0	yes	7.700	0.000	EPSD;PhosphoSitePlus	TCGA;ICGC	2.642	Loss
CMGC_CDK_CDK4_CDK4_ST	P21333	FLNA	P11802	CDK4	S1533	D1527E	1527	Missense	distal	-6	no	8.319	8.195	EPSD	TCGA;ICGC;COSMIC	2.642	Down-regulation
CMGC_CDK_CDK4_CDK4_ST	P21333	FLNA	P11802	CDK4	S1533	R1532L	1532	Missense	proximal	-1	no	8.319	8.460	EPSD	TCGA;ICGC;COSMIC	2.642	Up-regulation
CMGC_CDK_CDK4_CDK4_ST	P21333	FLNA	P11802	CDK4	S1630	R1635C	1635	Missense	distal	5	no	8.722	8.739	EPSD	TCGA;ICGC;COSMIC	2.642	Up-regulation
CMGC_CDK_CDK4_CDK4_ST	P21333	FLNA	P11802	CDK4	S1630	P1628L	1628	Missense	proximal	-2	no	8.722	8.194	EPSD	TCGA;ICGC;COSMIC	2.642	Down-regulation
CMGC_CDK_CDK4_CDK4_ST	P21333	FLNA	P11802	CDK4	S1630	P1631S	1631	Missense	proximal	1	no	8.722	2.535	EPSD	TCGA;ICGC;COSMIC	2.642	Loss
CMGC_CDK_CDK4_CDK4_ST	P21333	FLNA	P11802	CDK4	S1630	V1637M	1637	Missense	distal	7	no	8.722	8.725	EPSD	TCGA;ICGC;COSMIC;CCLE	2.642	Up-regulation
CMGC_CDK_CDK4_CDK4_ST	P21333	FLNA	P11802	CDK4	S1630	R1633H	1633	Missense	distal	3	no	8.722	8.356	EPSD	TCGA;ICGC;COSMIC;GDSC;CCLE	2.642	Down-regulation
CMGC_CDK_CDK4_CDK4_ST	P21333	FLNA	P11802	CDK4	S1734	N1733S	1733	Missense	proximal	-1	no	8.294	8.094	EPSD	TCGA;COSMIC	2.642	Down-regulation
CMGC_CDK_CDK4_CDK4_ST	P21333	FLNA	P11802	CDK4	S1854	D1847G	1847	Missense	distal	-7	no	8.438	8.139	EPSD	TCGA;COSMIC	2.642	Down-regulation
CMGC_CDK_CDK4_CDK4_ST	P21333	FLNA	P11802	CDK4	S1906	E1909Q	1909	Missense	distal	3	no	3.069	3.000	EPSD	TCGA;COSMIC	2.642	Down-regulation
CMGC_CDK_CDK4_CDK4_ST	P21333	FLNA	P11802	CDK4	S1906	S1899F	1899	Missense	distal	-7	no	3.069	2.356	EPSD	TCGA;COSMIC	2.642	Loss
CMGC_CDK_CDK4_CDK4_ST	P21333	FLNA	P11802	CDK4	S1906	T1913A	1913	Missense	distal	7	no	3.069	3.075	EPSD	TCGA;COSMIC	2.642	Up-regulation
CMGC_CDK_CDK4_CDK4_ST	P21333	FLNA	P11802	CDK4	S1961	M1958I	1958	Missense	distal	-3	no	2.732	2.761	EPSD	TCGA;ICGC;COSMIC	2.642	Up-regulation
CMGC_CDK_CDK4_CDK4_ST	P21333	FLNA	P11802	CDK4	S1961	S1961P	1961	Missense	central	0	yes	2.732	0.000	EPSD	TCGA;COSMIC	2.642	Loss
CMGC_CDK_CDK4_CDK4_ST	P21333	FLNA	P11802	CDK4	S1961	R1959C	1959	Missense	proximal	-2	no	2.732	2.648	EPSD	TCGA;COSMIC;GDSC	2.642	Down-regulation
CMGC_CDK_CDK4_CDK4_ST	P21333	FLNA	P11802	CDK4	S1961	M1958L	1958	Missense	distal	-3	no	2.732	2.757	EPSD	TCGA;COSMIC	2.642	Up-regulation
CMGC_CDK_CDK4_CDK4_ST	P21333	FLNA	P11802	CDK4	S2033	V2030M	2030	Missense	distal	-3	no	10.465	10.448	EPSD	TCGA;COSMIC	2.642	Down-regulation
CMGC_CDK_CDK4_CDK4_ST	P21333	FLNA	P11802	CDK4	S2033	P2036L	2036	Missense	distal	3	no	10.465	9.567	EPSD	TCGA;COSMIC	2.642	Down-regulation
CMGC_CDK_CDK4_CDK4_ST	P21333	FLNA	P11802	CDK4	S2128	S2131Y	2131	Missense	distal	3	no	9.970	9.416	EPSD	TCGA;COSMIC	2.642	Down-regulation
CMGC_CDK_CDK4_CDK4_ST	P21333	FLNA	P11802	CDK4	S2128	G2127D	2127	Missense	proximal	-1	no	9.970	9.777	EPSD	TCGA;COSMIC	2.642	Down-regulation
CMGC_CDK_CDK4_CDK4_ST	P21333	FLNA	P11802	CDK4	S2180	Q2177H	2177	Missense	distal	-3	no	7.171	7.179	EPSD	TCGA;COSMIC	2.642	Up-regulation
CMGC_CDK_CDK4_CDK4_ST	P21333	FLNA	P11802	CDK4	S2224	V2230L	2230	Missense	distal	6	no	9.496	9.514	EPSD	TCGA;COSMIC	2.642	Up-regulation
CMGC_CDK_CDK4_CDK4_ST	P21333	FLNA	P11802	CDK4	S2224	V2230M	2230	Missense	distal	6	no	9.496	9.507	EPSD	TCGA;COSMIC;GDSC;CCLE	2.642	Up-regulation
CMGC_CDK_CDK4_CDK4_ST	P21333	FLNA	P11802	CDK4	S2319	V2322M	2322	Missense	distal	3	no	8.717	8.812	EPSD	TCGA;COSMIC	2.642	Up-regulation
CMGC_CDK_CDK4_CDK4_ST	P21333	FLNA	P11802	CDK4	S2319	P2324H	2324	Missense	distal	5	no	8.717	8.763	EPSD	TCGA;COSMIC	2.642	Up-regulation
CMGC_CDK_CDK4_CDK4_ST	P21333	FLNA	P11802	CDK4	S2327	P2328T	2328	Missense	proximal	1	no	6.517	-0.009	EPSD	TCGA;ICGC;COSMIC	2.642	Loss
CMGC_CDK_CDK4_CDK4_ST	P21333	FLNA	P11802	CDK4	S2327	P2328L	2328	Missense	proximal	1	no	6.517	-1.062	EPSD	TCGA;COSMIC	2.642	Loss
CMGC_CDK_CDK4_CDK4_ST	P21333	FLNA	P11802	CDK4	S2327	V2322M	2322	Missense	distal	-5	no	6.517	6.532	EPSD	TCGA;COSMIC	2.642	Up-regulation
CMGC_CDK_CDK4_CDK4_ST	P21333	FLNA	P11802	CDK4	S2327	R2334H	2334	Missense	distal	7	no	6.517	6.510	EPSD	TCGA;COSMIC;GDSC;CCLE	2.642	Down-regulation
CMGC_CDK_CDK4_CDK4_ST	P21333	FLNA	P11802	CDK4	S2327	P2324H	2324	Missense	distal	-3	no	6.517	6.740	EPSD	TCGA;COSMIC	2.642	Up-regulation
CMGC_CDK_CDK4_CDK4_ST	P21333	FLNA	P11802	CDK4	S2327	A2332T	2332	Missense	distal	5	no	6.517	6.525	EPSD	TCGA;COSMIC	2.642	Up-regulation
CMGC_CDK_CDK4_CDK4_ST	P21333	FLNA	P11802	CDK4	S2343	N2348D	2348	Missense	distal	5	no	3.429	3.442	EPSD	TCGA;COSMIC	2.642	Up-regulation
CMGC_CDK_CDK4_CDK4_ST	P21333	FLNA	P11802	CDK4	S2343	E2342K	2342	Missense	proximal	-1	no	3.429	3.338	EPSD	TCGA	2.642	Down-regulation
CMGC_CDK_CDK4_CDK4_ST	P21333	FLNA	P11802	CDK4	S2352	G2359V	2359	Missense	distal	7	no	3.806	3.815	EPSD	TCGA;COSMIC	2.642	Up-regulation
CMGC_CDK_CDK4_CDK4_ST	P21333	FLNA	P11802	CDK4	S2352	S2352Y	2352	Missense	central	0	yes	3.806	0.000	EPSD	TCGA;COSMIC	2.642	Loss
CMGC_CDK_CDK4_CDK4_ST	P21333	FLNA	P11802	CDK4	S2370	S2372L	2372	Missense	proximal	2	no	8.154	7.927	EPSD	TCGA;COSMIC	2.642	Down-regulation
CMGC_CDK_CDK4_CDK4_ST	P21333	FLNA	P11802	CDK4	S2370	H2369Y	2369	Missense	proximal	-1	no	8.154	8.107	EPSD	TCGA;COSMIC	2.642	Down-regulation
CMGC_CDK_CDK4_CDK4_ST	P21333	FLNA	P11802	CDK4	S2370	A2363V	2363	Missense	distal	-7	no	8.154	7.668	EPSD	TCGA;COSMIC	2.642	Down-regulation
CMGC_CDK_CDK4_CDK4_ST	P21333	FLNA	P11802	CDK4	S2370	P2371L	2371	Missense	proximal	1	no	8.154	0.575	EPSD	TCGA;COSMIC	2.642	Loss
CMGC_CDK_CDK4_CDK4_ST	P21333	FLNA	P11802	CDK4	S2370	A2374S	2374	Missense	distal	4	no	8.154	8.062	EPSD	TCGA;COSMIC	2.642	Down-regulation
CMGC_CDK_CDK4_CDK4_ST	P21333	FLNA	P11802	CDK4	S2414	P2415S	2415	Missense	proximal	1	no	10.927	4.740	EPSD	TCGA	2.642	Down-regulation
CMGC_CDK_CDK4_CDK4_ST	P21333	FLNA	P11802	CDK4	T2488	A2491S	2491	Missense	distal	3	no	6.404	6.733	EPSD	TCGA;COSMIC	2.642	Up-regulation
CMGC_CDK_CDK4_CDK4_ST	P21333	FLNA	P11802	CDK4	T2488	V2485A	2485	Missense	distal	-3	no	6.404	6.292	EPSD	TCGA;COSMIC	2.642	Down-regulation
CMGC_CDK_CDK4_CDK4_ST	P21333	FLNA	P11802	CDK4	T2488	R2484H	2484	Missense	distal	-4	no	6.404	6.405	EPSD	TCGA	2.642	Up-regulation
CMGC_CDK_CDK4_CDK4_ST	P21333	FLNA	P11802	CDK4	S2510	F2512L	2512	Missense	proximal	2	no	6.664	6.737	EPSD	TCGA;COSMIC	2.642	Up-regulation
CMGC_CDK_CDK4_CDK4_ST	P21333	FLNA	P11802	CDK4	S2510	A2514V	2514	Missense	distal	4	no	6.664	6.961	EPSD	TCGA	2.642	Up-regulation
CMGC_CDK_CDK4_CDK4_ST	P21333	FLNA	P11802	CDK4	T2599	P2600L	2600	Missense	proximal	1	no	7.664	0.085	EPSD	TCGA;COSMIC	2.642	Loss
CMGC_CDK_CDK4_CDK4_ST	P21333	FLNA	P11802	CDK4	T2599	E2602D	2602	Missense	distal	3	no	7.664	7.370	EPSD	TCGA;COSMIC	2.642	Down-regulation
CMGC_CDK_CDK4_CDK4_ST	P21333	FLNA	P11802	CDK4	T2599	E2603K	2603	Missense	distal	4	no	7.664	7.614	EPSD	TCGA;COSMIC	2.642	Down-regulation
CMGC_CDK_CDK4_CDK4_ST	P21333	FLNA	P11802	CDK4	S2640	D2634N	2634	Missense	distal	-6	no	8.982	8.861	EPSD	TCGA;COSMIC	2.642	Down-regulation
CMGC_CDK_CDK4_CDK4_ST	P21333	FLNA	P11802	CDK4	S2640	R2643H	2643	Missense	distal	3	no	8.982	8.616	EPSD	TCGA;COSMIC	2.642	Down-regulation
CMGC_CDK_CDK4_CDK4_ST	P21333	FLNA	P11802	CDK4	S2640	E2635K	2635	Missense	distal	-5	no	8.982	8.969	EPSD	TCGA;COSMIC	2.642	Down-regulation
CMGC_CDK_CDK4_CDK4_ST	P21333	FLNA	P11802	CDK4	S2640	I2637N	2637	Missense	distal	-3	no	8.982	8.896	EPSD	TCGA;COSMIC	2.642	Down-regulation
CMGC_CDK_CDK4_CDK4_ST	P04179	SOD2	P11802	CDK4	S106	G110D	110	Missense	distal	4	no	7.812	7.637	PhosphoSitePlus	TCGA;COSMIC	2.642	Down-regulation
CMGC_CDK_CDK4_CDK4_ST	P04179	SOD2	P11802	CDK4	S127	G126A	126	Missense	proximal	-1	no	4.127	3.688	EPSD	TCGA;COSMIC	2.642	Down-regulation
CMGC_CDK_CDK4_CDK4_ST	P04179	SOD2	P11802	CDK4	S127	R123H	123	Missense	distal	-4	no	4.127	4.128	EPSD	TCGA;COSMIC	2.642	Up-regulation
CMGC_CDK_CDK4_CDK4_ST	P04179	SOD2	P11802	CDK4	S127	S127F	127	Missense	central	0	yes	4.127	0.000	EPSD	TCGA;COSMIC	2.642	Loss
CMGC_CDK_CDK4_CDK4_ST	O15151	MDM4	P11802	CDK4	S20	Q26E	26	Missense	distal	6	no	8.538	8.568	EPSD	TCGA;ICGC;COSMIC	2.642	Up-regulation
CMGC_CDK_CDK4_CDK4_ST	O15151	MDM4	P11802	CDK4	S20	R18S	18	Missense	proximal	-2	no	8.538	8.653	EPSD	TCGA;ICGC	2.642	Up-regulation
CMGC_CDK_CDK4_CDK4_ST	O15151	MDM4	P11802	CDK4	S96	D100N	100	Missense	distal	4	no	7.900	7.733	EPSD	TCGA;ICGC;COSMIC	2.642	Down-regulation
CMGC_CDK_CDK4_CDK4_ST	O15151	MDM4	P11802	CDK4	S314	K317N	317	Missense	distal	3	no	8.711	8.496	PhosphoSitePlus	TCGA;ICGC;COSMIC	2.642	Down-regulation
CMGC_CDK_CDK4_CDK4_ST	O15151	MDM4	P11802	CDK4	S314	C309S	309	Missense	distal	-5	no	8.711	8.869	PhosphoSitePlus	TCGA;COSMIC	2.642	Up-regulation
CMGC_CDK_CDK4_CDK4_ST	O15151	MDM4	P11802	CDK4	S314	E308A	308	Missense	distal	-6	no	8.711	8.602	PhosphoSitePlus	TCGA;ICGC;COSMIC	2.642	Down-regulation
CMGC_CDK_CDK4_CDK4_ST	P04637	TP53	P11802	CDK4	S33	P27S	27	Missense	distal	-6	no	7.064	6.854	EPSD	TCGA;ICGC;COSMIC	2.642	Down-regulation
CMGC_CDK_CDK4_CDK4_ST	P04637	TP53	P11802	CDK4	S33	P27L	27	Missense	distal	-6	no	7.064	7.217	EPSD	TCGA;ICGC;COSMIC;GDSC;CCLE	2.642	Up-regulation
CMGC_CDK_CDK4_CDK4_ST	P04637	TP53	P11802	CDK4	S46	D48N	48	Missense	proximal	2	no	6.809	6.901	EPSD	TCGA;ICGC;COSMIC;GDSC;CCLE	2.642	Up-regulation
CMGC_CDK_CDK4_CDK4_ST	P04637	TP53	P11802	CDK4	T81	A79V	79	Missense	proximal	-2	no	8.060	7.933	EPSD	TCGA;ICGC;COSMIC	2.642	Down-regulation
CMGC_CDK_CDK4_CDK4_ST	P04637	TP53	P11802	CDK4	T81	P77L	77	Missense	distal	-4	no	8.060	8.061	EPSD	TCGA;ICGC;COSMIC	2.642	Up-regulation
CMGC_CDK_CDK4_CDK4_ST	P04637	TP53	P11802	CDK4	T81	P82L	82	Missense	proximal	1	no	8.060	0.481	EPSD	TCGA;ICGC;COSMIC	2.642	Loss
CMGC_CDK_CDK4_CDK4_ST	P04637	TP53	P11802	CDK4	T81	A74T	74	Missense	distal	-7	no	8.060	7.866	EPSD	TCGA;ICGC;COSMIC	2.642	Down-regulation
CMGC_CDK_CDK4_CDK4_ST	P04637	TP53	P11802	CDK4	S127	K132N	132	Missense	distal	5	no	7.138	7.143	EPSD	TCGA;ICGC;COSMIC;GDSC;CCLE	2.642	Up-regulation
CMGC_CDK_CDK4_CDK4_ST	P04637	TP53	P11802	CDK4	S127	S121Y	121	Missense	distal	-6	no	7.138	7.434	EPSD	TCGA;ICGC;COSMIC	2.642	Up-regulation
CMGC_CDK_CDK4_CDK4_ST	P04637	TP53	P11802	CDK4	S127	M133K	133	Missense	distal	6	no	7.138	7.233	EPSD	TCGA;ICGC;COSMIC;CCLE	2.642	Up-regulation
CMGC_CDK_CDK4_CDK4_ST	P04637	TP53	P11802	CDK4	S127	K132E	132	Missense	distal	5	no	7.138	7.145	EPSD	TCGA;ICGC;COSMIC;GDSC;CCLE	2.642	Up-regulation
CMGC_CDK_CDK4_CDK4_ST	P04637	TP53	P11802	CDK4	S127	Y126C	126	Missense	proximal	-1	no	7.138	7.231	EPSD	TCGA;ICGC;COSMIC;GDSC	2.642	Up-regulation
CMGC_CDK_CDK4_CDK4_ST	P04637	TP53	P11802	CDK4	S127	S127P	127	Missense	central	0	yes	7.138	0.000	EPSD	TCGA;ICGC;COSMIC;GDSC;CCLE	2.642	Loss
CMGC_CDK_CDK4_CDK4_ST	P04637	TP53	P11802	CDK4	S127	Y126N	126	Missense	proximal	-1	no	7.138	7.092	EPSD	TCGA;ICGC;COSMIC	2.642	Down-regulation
CMGC_CDK_CDK4_CDK4_ST	P04637	TP53	P11802	CDK4	S127	L130V	130	Missense	distal	3	no	7.138	6.980	EPSD	TCGA;ICGC;COSMIC;GDSC;CCLE	2.642	Down-regulation
CMGC_CDK_CDK4_CDK4_ST	P04637	TP53	P11802	CDK4	S127	K132T	132	Missense	distal	5	no	7.138	7.140	EPSD	TCGA;ICGC;COSMIC;GDSC;CCLE	2.642	Up-regulation
CMGC_CDK_CDK4_CDK4_ST	P04637	TP53	P11802	CDK4	S127	S127Y	127	Missense	central	0	yes	7.138	0.000	EPSD	TCGA;ICGC;COSMIC	2.642	Loss
CMGC_CDK_CDK4_CDK4_ST	P04637	TP53	P11802	CDK4	S127	S127F	127	Missense	central	0	yes	7.138	0.000	EPSD	TCGA;ICGC;COSMIC;CCLE	2.642	Loss
CMGC_CDK_CDK4_CDK4_ST	P04637	TP53	P11802	CDK4	S127	M133R	133	Missense	distal	6	no	7.138	7.213	EPSD	TCGA;ICGC;COSMIC	2.642	Up-regulation
CMGC_CDK_CDK4_CDK4_ST	P04637	TP53	P11802	CDK4	S127	K132R	132	Missense	distal	5	no	7.138	7.141	EPSD	TCGA;ICGC;COSMIC;GDSC;CCLE	2.642	Up-regulation
CMGC_CDK_CDK4_CDK4_ST	P04637	TP53	P11802	CDK4	S127	Y126S	126	Missense	proximal	-1	no	7.138	6.892	EPSD	TCGA;ICGC;COSMIC	2.642	Down-regulation
CMGC_CDK_CDK4_CDK4_ST	P04637	TP53	P11802	CDK4	S127	L130P	130	Missense	distal	3	no	7.138	8.037	EPSD	TCGA;ICGC;COSMIC	2.642	Up-regulation
CMGC_CDK_CDK4_CDK4_ST	P04637	TP53	P11802	CDK4	S127	L130F	130	Missense	distal	3	no	7.138	7.141	EPSD	TCGA;ICGC;COSMIC;CCLE	2.642	Up-regulation
CMGC_CDK_CDK4_CDK4_ST	P04637	TP53	P11802	CDK4	S127	T125M	125	Missense	proximal	-2	no	7.138	7.083	EPSD	TCGA;ICGC;COSMIC;GDSC	2.642	Down-regulation
CMGC_CDK_CDK4_CDK4_ST	P04637	TP53	P11802	CDK4	S127	Y126D	126	Missense	proximal	-1	no	7.138	7.215	EPSD	TCGA;ICGC;COSMIC;GDSC	2.642	Up-regulation
CMGC_CDK_CDK4_CDK4_ST	P04637	TP53	P11802	CDK4	S127	K120E	120	Missense	distal	-7	no	7.138	7.182	EPSD	TCGA;ICGC;COSMIC	2.642	Up-regulation
CMGC_CDK_CDK4_CDK4_ST	P04637	TP53	P11802	CDK4	S127	N131S	131	Missense	distal	4	no	7.138	6.912	EPSD	TCGA;ICGC;COSMIC	2.642	Down-regulation
CMGC_CDK_CDK4_CDK4_ST	P04637	TP53	P11802	CDK4	S127	T125P	125	Missense	proximal	-2	no	7.138	7.560	EPSD	TCGA;ICGC;COSMIC;CCLE	2.642	Up-regulation
CMGC_CDK_CDK4_CDK4_ST	P04637	TP53	P11802	CDK4	S127	S127C	127	Missense	central	0	yes	7.138	0.000	EPSD	TCGA;ICGC;COSMIC;CCLE	2.642	Loss
CMGC_CDK_CDK4_CDK4_ST	P04637	TP53	P11802	CDK4	S127	N131I	131	Missense	distal	4	no	7.138	7.302	EPSD	TCGA;ICGC;COSMIC	2.642	Up-regulation
CMGC_CDK_CDK4_CDK4_ST	P04637	TP53	P11802	CDK4	S127	Y126H	126	Missense	proximal	-1	no	7.138	7.185	EPSD	TCGA;ICGC;COSMIC;GDSC	2.642	Up-regulation
CMGC_CDK_CDK4_CDK4_ST	P04637	TP53	P11802	CDK4	S127	K132Q	132	Missense	distal	5	no	7.138	7.149	EPSD	TCGA;ICGC;COSMIC;GDSC;CCLE	2.642	Up-regulation
CMGC_CDK_CDK4_CDK4_ST	P04637	TP53	P11802	CDK4	S127	L130R	130	Missense	distal	3	no	7.138	7.490	EPSD	TCGA;ICGC;COSMIC;CCLE	2.642	Up-regulation
CMGC_CDK_CDK4_CDK4_ST	P04637	TP53	P11802	CDK4	S149	V143G	143	Missense	distal	-6	no	2.468	2.659	EPSD	TCGA;ICGC;COSMIC	2.642	Gain
CMGC_CDK_CDK4_CDK4_ST	P04637	TP53	P11802	CDK4	T150	W146S	146	Missense	distal	-4	no	7.199	7.198	EPSD	TCGA;ICGC;COSMIC	2.642	Down-regulation
CMGC_CDK_CDK4_CDK4_ST	P04637	TP53	P11802	CDK4	T150	P152L	152	Missense	proximal	2	no	7.199	7.130	EPSD	TCGA;ICGC;COSMIC;GDSC;CCLE	2.642	Down-regulation
CMGC_CDK_CDK4_CDK4_ST	P04637	TP53	P11802	CDK4	T150	D148N	148	Missense	proximal	-2	no	7.199	7.272	EPSD	TCGA;ICGC;COSMIC	2.642	Up-regulation
CMGC_CDK_CDK4_CDK4_ST	P04637	TP53	P11802	CDK4	T150	P151H	151	Missense	proximal	1	no	7.199	0.616	EPSD	TCGA;ICGC;COSMIC;GDSC;CCLE	2.642	Loss
CMGC_CDK_CDK4_CDK4_ST	P04637	TP53	P11802	CDK4	T150	P151A	151	Missense	proximal	1	no	7.199	0.261	EPSD	TCGA;ICGC;COSMIC;CCLE	2.642	Loss
CMGC_CDK_CDK4_CDK4_ST	P04637	TP53	P11802	CDK4	T150	R156P	156	Missense	distal	6	no	7.199	7.153	EPSD	TCGA;ICGC;COSMIC;GDSC;CCLE	2.642	Down-regulation
CMGC_CDK_CDK4_CDK4_ST	P04637	TP53	P11802	CDK4	T150	V143A	143	Missense	distal	-7	no	7.199	7.684	EPSD	TCGA;ICGC;COSMIC;GDSC;CCLE	2.642	Up-regulation
CMGC_CDK_CDK4_CDK4_ST	P04637	TP53	P11802	CDK4	T150	P151S	151	Missense	proximal	1	no	7.199	1.012	EPSD	TCGA;ICGC;COSMIC;GDSC;CCLE	2.642	Loss
CMGC_CDK_CDK4_CDK4_ST	P04637	TP53	P11802	CDK4	T150	V157G	157	Missense	distal	7	no	7.199	7.190	EPSD	TCGA;ICGC;COSMIC	2.642	Down-regulation
CMGC_CDK_CDK4_CDK4_ST	P04637	TP53	P11802	CDK4	T150	L145R	145	Missense	distal	-5	no	7.199	7.242	EPSD	TCGA;ICGC;COSMIC;GDSC;CCLE	2.642	Up-regulation
CMGC_CDK_CDK4_CDK4_ST	P04637	TP53	P11802	CDK4	T150	T155I	155	Missense	distal	5	no	7.199	7.217	EPSD	TCGA;ICGC;COSMIC;CCLE	2.642	Up-regulation
CMGC_CDK_CDK4_CDK4_ST	P04637	TP53	P11802	CDK4	T150	V143M	143	Missense	distal	-7	no	7.199	7.276	EPSD	TCGA;ICGC;COSMIC;GDSC;CCLE	2.642	Up-regulation
CMGC_CDK_CDK4_CDK4_ST	P04637	TP53	P11802	CDK4	T150	T155N	155	Missense	distal	5	no	7.199	7.201	EPSD	TCGA;ICGC;COSMIC;GDSC;CCLE	2.642	Up-regulation
CMGC_CDK_CDK4_CDK4_ST	P04637	TP53	P11802	CDK4	T150	P152S	152	Missense	proximal	2	no	7.199	7.358	EPSD	TCGA;ICGC;COSMIC;CCLE	2.642	Up-regulation
CMGC_CDK_CDK4_CDK4_ST	P04637	TP53	P11802	CDK4	T150	R156C	156	Missense	distal	6	no	7.199	7.093	EPSD	TCGA;ICGC;COSMIC	2.642	Down-regulation
CMGC_CDK_CDK4_CDK4_ST	P04637	TP53	P11802	CDK4	T150	P151T	151	Missense	proximal	1	no	7.199	0.672	EPSD	TCGA;ICGC;COSMIC	2.642	Loss
CMGC_CDK_CDK4_CDK4_ST	P04637	TP53	P11802	CDK4	T150	T155P	155	Missense	distal	5	no	7.199	7.163	EPSD	TCGA;ICGC;COSMIC;CCLE	2.642	Down-regulation
CMGC_CDK_CDK4_CDK4_ST	P04637	TP53	P11802	CDK4	T150	V143G	143	Missense	distal	-7	no	7.199	6.987	EPSD	TCGA;ICGC;COSMIC	2.642	Down-regulation
CMGC_CDK_CDK4_CDK4_ST	P04637	TP53	P11802	CDK4	T150	P152Q	152	Missense	proximal	2	no	7.199	7.128	EPSD	TCGA;ICGC;COSMIC	2.642	Down-regulation
CMGC_CDK_CDK4_CDK4_ST	P04637	TP53	P11802	CDK4	T150	R156H	156	Missense	distal	6	no	7.199	7.125	EPSD	TCGA;ICGC;COSMIC	2.642	Down-regulation
CMGC_CDK_CDK4_CDK4_ST	P04637	TP53	P11802	CDK4	T150	L145P	145	Missense	distal	-5	no	7.199	7.214	EPSD	TCGA;ICGC;COSMIC	2.642	Up-regulation
CMGC_CDK_CDK4_CDK4_ST	P04637	TP53	P11802	CDK4	T150	Q144L	144	Missense	distal	-6	no	7.199	7.286	EPSD	TCGA;ICGC;COSMIC	2.642	Up-regulation
CMGC_CDK_CDK4_CDK4_ST	P04637	TP53	P11802	CDK4	T150	Q144H	144	Missense	distal	-6	no	7.199	7.238	EPSD	TCGA;ICGC;COSMIC	2.642	Up-regulation
CMGC_CDK_CDK4_CDK4_ST	P04637	TP53	P11802	CDK4	T150	G154V	154	Missense	distal	4	no	7.199	7.020	EPSD	TCGA;ICGC;COSMIC;GDSC;CCLE	2.642	Down-regulation
CMGC_CDK_CDK4_CDK4_ST	P04637	TP53	P11802	CDK4	T150	P151R	151	Missense	proximal	1	no	7.199	0.412	EPSD	TCGA;ICGC;COSMIC	2.642	Loss
CMGC_CDK_CDK4_CDK4_ST	P04637	TP53	P11802	CDK4	T150	Q144P	144	Missense	distal	-6	no	7.199	7.133	EPSD	TCGA;ICGC;COSMIC	2.642	Down-regulation
CMGC_CDK_CDK4_CDK4_ST	P04637	TP53	P11802	CDK4	T150	V143E	143	Missense	distal	-7	no	7.199	7.516	EPSD	TCGA;ICGC;COSMIC	2.642	Up-regulation
CMGC_CDK_CDK4_CDK4_ST	P04637	TP53	P11802	CDK4	T150	R156G	156	Missense	distal	6	no	7.199	7.014	EPSD	TCGA;ICGC;COSMIC	2.642	Down-regulation
CMGC_CDK_CDK4_CDK4_ST	P04637	TP53	P11802	CDK4	T150	P151L	151	Missense	proximal	1	no	7.199	-0.380	EPSD	TCGA;ICGC;COSMIC	2.642	Loss
CMGC_CDK_CDK4_CDK4_ST	P04637	TP53	P11802	CDK4	T155	R156P	156	Missense	proximal	1	no	0.514	7.301	EPSD	TCGA;ICGC;COSMIC;GDSC;CCLE	2.642	Gain
CMGC_CDK_CDK4_CDK4_ST	P04637	TP53	P11802	CDK4	S315	K319N	319	Missense	distal	4	no	8.449	8.500	EPSD	TCGA;ICGC;COSMIC	2.642	Up-regulation
CMGC_CDK_CDK4_CDK4_ST	P04637	TP53	P11802	CDK4	S315	K320E	320	Missense	distal	5	no	8.449	8.456	EPSD	TCGA;ICGC;COSMIC	2.642	Up-regulation
CMGC_CDK_CDK4_CDK4_ST	P04637	TP53	P11802	CDK4	S315	S315C	315	Missense	central	0	yes	8.449	0.000	EPSD	TCGA;ICGC;COSMIC	2.642	Loss
CMGC_CDK_CDK4_CDK4_ST	P28749	RBL1	P11802	CDK4	T332	A326T	326	Missense	distal	-6	no	7.964	8.052	EPSD	TCGA;ICGC;COSMIC	2.642	Up-regulation
CMGC_CDK_CDK4_CDK4_ST	P28749	RBL1	P11802	CDK4	T332	R338C	338	Missense	distal	6	no	7.964	7.859	EPSD	TCGA;ICGC;COSMIC	2.642	Down-regulation
CMGC_CDK_CDK4_CDK4_ST	P28749	RBL1	P11802	CDK4	T332	R334Q	334	Missense	proximal	2	no	7.964	7.856	EPSD	TCGA;ICGC;COSMIC	2.642	Down-regulation
CMGC_CDK_CDK4_CDK4_ST	P28749	RBL1	P11802	CDK4	T332	R338H	338	Missense	distal	6	no	7.964	7.890	EPSD	TCGA;ICGC;COSMIC;GDSC	2.642	Down-regulation
CMGC_CDK_CDK4_CDK4_ST	P28749	RBL1	P11802	CDK4	T340	R338C	338	Missense	proximal	-2	no	6.833	6.748	EPSD	TCGA;ICGC;COSMIC	2.642	Down-regulation
CMGC_CDK_CDK4_CDK4_ST	P28749	RBL1	P11802	CDK4	T340	R334Q	334	Missense	distal	-6	no	6.833	6.838	EPSD	TCGA;ICGC;COSMIC	2.642	Up-regulation
CMGC_CDK_CDK4_CDK4_ST	P28749	RBL1	P11802	CDK4	T340	R338H	338	Missense	proximal	-2	no	6.833	6.797	EPSD	TCGA;ICGC;COSMIC;GDSC	2.642	Down-regulation
CMGC_CDK_CDK4_CDK4_ST	P28749	RBL1	P11802	CDK4	T369	Y376H	376	Missense	distal	7	no	7.842	7.840	EPSD;PhosphoSitePlus	TCGA	2.642	Down-regulation
CMGC_CDK_CDK4_CDK4_ST	P28749	RBL1	P11802	CDK4	T385	S389L	389	Missense	distal	4	no	6.496	6.863	EPSD	TCGA;ICGC;COSMIC	2.642	Up-regulation
CMGC_CDK_CDK4_CDK4_ST	P28749	RBL1	P11802	CDK4	T385	Q392K	392	Missense	distal	7	no	6.496	6.503	EPSD	TCGA;ICGC;COSMIC	2.642	Up-regulation
CMGC_CDK_CDK4_CDK4_ST	P28749	RBL1	P11802	CDK4	T385	A382S	382	Missense	distal	-3	no	6.496	6.432	EPSD	TCGA;ICGC	2.642	Down-regulation
CMGC_CDK_CDK4_CDK4_ST	P28749	RBL1	P11802	CDK4	S615	L617V	617	Missense	proximal	2	no	7.431	7.383	EPSD	TCGA;ICGC;COSMIC	2.642	Down-regulation
CMGC_CDK_CDK4_CDK4_ST	P28749	RBL1	P11802	CDK4	S615	M618I	618	Missense	distal	3	no	7.431	7.270	EPSD	TCGA;ICGC;COSMIC	2.642	Down-regulation
CMGC_CDK_CDK4_CDK4_ST	P28749	RBL1	P11802	CDK4	S629	R633Q	633	Missense	distal	4	no	3.690	3.756	EPSD	TCGA;ICGC;COSMIC	2.642	Up-regulation
CMGC_CDK_CDK4_CDK4_ST	P28749	RBL1	P11802	CDK4	S629	R626Q	626	Missense	distal	-3	no	3.690	3.725	EPSD	TCGA;ICGC;COSMIC	2.642	Up-regulation
CMGC_CDK_CDK4_CDK4_ST	P28749	RBL1	P11802	CDK4	S629	L632I	632	Missense	distal	3	no	3.690	3.466	EPSD	TCGA;ICGC	2.642	Down-regulation
CMGC_CDK_CDK4_CDK4_ST	P28749	RBL1	P11802	CDK4	S640	R633Q	633	Missense	distal	-7	no	10.648	10.590	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	2.642	Down-regulation
CMGC_CDK_CDK4_CDK4_ST	P28749	RBL1	P11802	CDK4	S640	R647C	647	Missense	distal	7	no	10.648	10.638	EPSD;PhosphoSitePlus	TCGA;ICGC	2.642	Down-regulation
CMGC_CDK_CDK4_CDK4_ST	P28749	RBL1	P11802	CDK4	S650	S650A	650	Missense	central	0	yes	9.588	0.000	EPSD	TCGA;ICGC;COSMIC	2.642	Loss
CMGC_CDK_CDK4_CDK4_ST	P28749	RBL1	P11802	CDK4	S650	A653T	653	Missense	distal	3	no	9.588	9.427	EPSD	TCGA;ICGC;COSMIC	2.642	Down-regulation
CMGC_CDK_CDK4_CDK4_ST	P28749	RBL1	P11802	CDK4	S650	S650F	650	Missense	central	0	yes	9.588	0.000	EPSD	TCGA;ICGC	2.642	Loss
CMGC_CDK_CDK4_CDK4_ST	P28749	RBL1	P11802	CDK4	S650	R647C	647	Missense	distal	-3	no	9.588	9.657	EPSD	TCGA;ICGC	2.642	Up-regulation
CMGC_CDK_CDK4_CDK4_ST	P28749	RBL1	P11802	CDK4	S749	K748N	748	Missense	proximal	-1	no	7.445	7.547	EPSD	TCGA;ICGC;COSMIC;CCLE	2.642	Up-regulation
CMGC_CDK_CDK4_CDK4_ST	P28749	RBL1	P11802	CDK4	S749	H756N	756	Missense	distal	7	no	7.445	7.451	EPSD	TCGA;ICGC;COSMIC	2.642	Up-regulation
CMGC_CDK_CDK4_CDK4_ST	P28749	RBL1	P11802	CDK4	S762	S757L	757	Missense	distal	-5	no	6.469	6.318	EPSD	TCGA;ICGC;COSMIC	2.642	Down-regulation
CMGC_CDK_CDK4_CDK4_ST	P28749	RBL1	P11802	CDK4	S762	H756N	756	Missense	distal	-6	no	6.469	6.367	EPSD	TCGA;ICGC;COSMIC	2.642	Down-regulation
CMGC_CDK_CDK4_CDK4_ST	P28749	RBL1	P11802	CDK4	T915	C918S	918	Missense	distal	3	no	6.714	7.397	EPSD	TCGA;ICGC;COSMIC	2.642	Up-regulation
CMGC_CDK_CDK4_CDK4_ST	P28749	RBL1	P11802	CDK4	S964	P965L	965	Missense	proximal	1	no	8.450	0.871	PhosphoSitePlus;EPSD	TCGA;ICGC;COSMIC	2.642	Loss
CMGC_CDK_CDK4_CDK4_ST	P28749	RBL1	P11802	CDK4	S964	P965S	965	Missense	proximal	1	no	8.450	2.263	PhosphoSitePlus;EPSD	TCGA;ICGC;COSMIC	2.642	Loss
CMGC_CDK_CDK4_CDK4_ST	P28749	RBL1	P11802	CDK4	S964	A960D	960	Missense	distal	-4	no	8.450	8.451	PhosphoSitePlus;EPSD	TCGA;ICGC;COSMIC	2.642	Up-regulation
CMGC_CDK_CDK4_CDK4_ST	P28749	RBL1	P11802	CDK4	S975	R978H	978	Missense	distal	3	no	7.914	7.547	EPSD;PhosphoSitePlus	TCGA;COSMIC	2.642	Down-regulation
CMGC_CDK_CDK4_CDK4_ST	P28749	RBL1	P11802	CDK4	S988	P989L	989	Missense	proximal	1	no	5.437	-2.142	EPSD	TCGA;ICGC;COSMIC	2.642	Loss
CMGC_CDK_CDK4_CDK4_ST	P28749	RBL1	P11802	CDK4	S994	P989L	989	Missense	distal	-5	no	3.474	3.459	EPSD	TCGA;ICGC;COSMIC	2.642	Down-regulation
CMGC_CDK_CDK4_CDK4_ST	P28749	RBL1	P11802	CDK4	S994	A1001T	1001	Missense	distal	7	no	3.474	3.468	EPSD	TCGA;ICGC;COSMIC	2.642	Down-regulation
CMGC_CDK_CDK4_CDK4_ST	P28749	RBL1	P11802	CDK4	S994	L996R	996	Missense	proximal	2	no	3.474	3.580	EPSD	TCGA;ICGC;COSMIC	2.642	Up-regulation
CMGC_CDK_CDK4_CDK4_ST	P28749	RBL1	P11802	CDK4	T997	A1001T	1001	Missense	distal	4	no	6.149	6.284	EPSD	TCGA;ICGC;COSMIC	2.642	Up-regulation
CMGC_CDK_CDK4_CDK4_ST	P28749	RBL1	P11802	CDK4	T997	L996R	996	Missense	proximal	-1	no	6.149	6.008	EPSD	TCGA;ICGC;COSMIC	2.642	Down-regulation
CMGC_CDK_CDK4_CDK4_ST	P28749	RBL1	P11802	CDK4	S1009	G1008V	1008	Missense	proximal	-1	no	7.843	7.641	EPSD	TCGA;ICGC;COSMIC	2.642	Down-regulation
CMGC_CDK_CDK4_CDK4_ST	P28749	RBL1	P11802	CDK4	S1009	G1008C	1008	Missense	proximal	-1	no	7.843	7.667	EPSD	TCGA;ICGC;COSMIC	2.642	Down-regulation
CMGC_CDK_CDK4_CDK4_ST	P28749	RBL1	P11802	CDK4	S1041	V1046F	1046	Missense	distal	5	no	8.778	8.769	EPSD	TCGA;ICGC;COSMIC	2.642	Down-regulation
CMGC_CDK_CDK4_CDK4_ST	P28749	RBL1	P11802	CDK4	S1041	A1034S	1034	Missense	distal	-7	no	8.778	8.995	EPSD	TCGA;ICGC	2.642	Up-regulation
CMGC_CDK_CDK4_CDK4_ST	P28749	RBL1	P11802	CDK4	S1041	R1045C	1045	Missense	distal	4	no	8.778	8.943	EPSD	TCGA;ICGC;COSMIC;CCLE	2.642	Up-regulation
CMGC_CDK_CDK4_CDK4_ST	P43694	GATA4	P11802	CDK4	S406	S401L	401	Missense	distal	-5	no	8.771	8.619	EPSD	TCGA;COSMIC	2.642	Down-regulation
CMGC_CDK_CDK4_CDK4_ST	O43791	SPOP	P11802	CDK4	S6	P10T	10	Missense	distal	4	no	8.610	8.630	PhosphoSitePlus	TCGA;ICGC;COSMIC	2.642	Up-regulation
CMGC_CDK_CDK4_CDK4_ST	Q9NS23	RASSF1	P11802	CDK4	S207	R205C	205	Missense	proximal	-2	no	4.882	4.798	EPSD	TCGA;COSMIC	2.642	Down-regulation
CMGC_CDK_CDK4_CDK4_ST	Q9NS23	RASSF1	P11802	CDK4	S207	V202A	202	Missense	distal	-5	no	4.882	4.989	EPSD	TCGA;COSMIC	2.642	Up-regulation
STE_STE11_MEKK2_MAP3K3_ST	P08151	GLI1	Q99759	MAP3K3	S69	R72Q	72	Missense	distal	3	no	12.155	12.553	EPSD	TCGA;ICGC;COSMIC	11.002	Up-regulation
STE_STE11_MEKK2_MAP3K3_ST	P08151	GLI1	Q99759	MAP3K3	S69	G65D	65	Missense	distal	-4	no	12.155	9.246	EPSD	TCGA;COSMIC	11.002	Loss
STE_STE11_MEKK2_MAP3K3_ST	P08151	GLI1	Q99759	MAP3K3	S69	S69Y	69	Missense	central	0	yes	12.155	0.000	EPSD	TCGA;ICGC	11.002	Loss
STE_STE11_MEKK2_MAP3K3_ST	P08151	GLI1	Q99759	MAP3K3	S89	I85M	85	Missense	distal	-4	no	11.297	8.508	EPSD	TCGA;COSMIC	11.002	Loss
STE_STE11_MEKK2_MAP3K3_ST	P08151	GLI1	Q99759	MAP3K3	S89	S89L	89	Missense	central	0	yes	11.297	0.000	EPSD	TCGA;COSMIC	11.002	Loss
STE_STE11_MEKK2_MAP3K3_ST	P08151	GLI1	Q99759	MAP3K3	S89	S84P	84	Missense	distal	-5	no	11.297	10.491	EPSD	TCGA;COSMIC	11.002	Loss
STE_STE11_MEKK2_MAP3K3_ST	P08151	GLI1	Q99759	MAP3K3	S89	D94Y	94	Missense	distal	5	no	11.297	11.007	EPSD	TCGA;COSMIC	11.002	Down-regulation
STE_STE11_MEKK2_MAP3K3_ST	P08151	GLI1	Q99759	MAP3K3	S201	S200C	200	Missense	proximal	-1	no	29.891	29.394	PhosphoSitePlus;EPSD	TCGA;COSMIC	11.002	Down-regulation
STE_STE11_MEKK2_MAP3K3_ST	P08151	GLI1	Q99759	MAP3K3	S201	G197S	197	Missense	distal	-4	no	29.891	30.957	PhosphoSitePlus;EPSD	TCGA;COSMIC	11.002	Up-regulation
STE_STE11_MEKK2_MAP3K3_ST	P08151	GLI1	Q99759	MAP3K3	S201	G197D	197	Missense	distal	-4	no	29.891	26.982	PhosphoSitePlus;EPSD	TCGA;COSMIC	11.002	Down-regulation
STE_STE11_MEKK2_MAP3K3_ST	P08151	GLI1	Q99759	MAP3K3	S201	Q208H	208	Missense	distal	7	no	29.891	28.948	PhosphoSitePlus;EPSD	TCGA;COSMIC	11.002	Down-regulation
STE_STE11_MEKK2_MAP3K3_ST	P08151	GLI1	Q99759	MAP3K3	S204	S200C	200	Missense	distal	-4	no	28.536	24.139	EPSD;PhosphoSitePlus	TCGA;COSMIC	11.002	Down-regulation
STE_STE11_MEKK2_MAP3K3_ST	P08151	GLI1	Q99759	MAP3K3	S204	D209Y	209	Missense	distal	5	no	28.536	28.246	EPSD;PhosphoSitePlus	TCGA;COSMIC	11.002	Down-regulation
STE_STE11_MEKK2_MAP3K3_ST	P08151	GLI1	Q99759	MAP3K3	S204	G197S	197	Missense	distal	-7	no	28.536	28.317	EPSD;PhosphoSitePlus	TCGA;COSMIC	11.002	Down-regulation
STE_STE11_MEKK2_MAP3K3_ST	P08151	GLI1	Q99759	MAP3K3	S204	G197D	197	Missense	distal	-7	no	28.536	29.214	EPSD;PhosphoSitePlus	TCGA;COSMIC	11.002	Up-regulation
STE_STE11_MEKK2_MAP3K3_ST	P08151	GLI1	Q99759	MAP3K3	S204	P210S	210	Missense	distal	6	no	28.536	28.743	EPSD;PhosphoSitePlus	TCGA;COSMIC	11.002	Up-regulation
STE_STE11_MEKK2_MAP3K3_ST	P08151	GLI1	Q99759	MAP3K3	S204	Q208H	208	Missense	distal	4	no	28.536	26.219	EPSD;PhosphoSitePlus	TCGA;COSMIC	11.002	Down-regulation
STE_STE11_MEKK2_MAP3K3_ST	P08151	GLI1	Q99759	MAP3K3	S243	C242Y	242	Missense	proximal	-1	no	28.806	29.011	EPSD;PhosphoSitePlus	TCGA	11.002	Up-regulation
STE_STE11_MEKK2_MAP3K3_ST	P08151	GLI1	Q99759	MAP3K3	S560	P564S	564	Missense	distal	4	no	9.857	11.154	EPSD	TCGA;COSMIC	11.002	Gain
STE_STE11_MEKK2_MAP3K3_ST	P08151	GLI1	Q99759	MAP3K3	S937	R940H	940	Missense	distal	3	no	10.150	11.970	EPSD	TCGA;GDSC;CCLE	11.002	Gain
STE_STE11_MEKK2_MAP3K3_ST	P08151	GLI1	Q99759	MAP3K3	S968	E972D	972	Missense	distal	4	no	28.505	28.373	EPSD;PhosphoSitePlus	TCGA;COSMIC	11.002	Down-regulation
STE_STE11_MEKK2_MAP3K3_ST	P08151	GLI1	Q99759	MAP3K3	S968	S963F	963	Missense	distal	-5	no	28.505	28.471	EPSD;PhosphoSitePlus	TCGA;COSMIC	11.002	Down-regulation
STE_STE11_MEKK2_MAP3K3_ST	P08151	GLI1	Q99759	MAP3K3	S1071	S1064F	1064	Missense	distal	-7	no	11.291	11.756	EPSD	TCGA;ICGC;COSMIC	11.002	Up-regulation
STE_STE11_MEKK2_MAP3K3_ST	P08151	GLI1	Q99759	MAP3K3	S1071	P1077L	1077	Missense	distal	6	no	11.291	11.575	EPSD	TCGA;COSMIC	11.002	Up-regulation
STE_STE11_MEKK2_MAP3K3_ST	P08151	GLI1	Q99759	MAP3K3	S1071	G1069S	1069	Missense	proximal	-2	no	11.291	10.917	EPSD	TCGA;COSMIC	11.002	Loss
STE_STE11_MEKK2_MAP3K3_ST	P08151	GLI1	Q99759	MAP3K3	S1071	S1070N	1070	Missense	proximal	-1	no	11.291	10.397	EPSD	TCGA	11.002	Loss
STE_STE11_MEKK2_MAP3K3_ST	P08151	GLI1	Q99759	MAP3K3	T1074	P1077L	1077	Missense	distal	3	no	30.679	32.624	EPSD;PhosphoSitePlus	TCGA;COSMIC	11.002	Up-regulation
STE_STE11_MEKK2_MAP3K3_ST	P08151	GLI1	Q99759	MAP3K3	T1074	G1069S	1069	Missense	distal	-5	no	30.679	30.320	EPSD;PhosphoSitePlus	TCGA;COSMIC	11.002	Down-regulation
STE_STE11_MEKK2_MAP3K3_ST	P08151	GLI1	Q99759	MAP3K3	T1074	S1070N	1070	Missense	distal	-4	no	30.679	27.252	EPSD;PhosphoSitePlus	TCGA	11.002	Down-regulation
STE_STE11_MEKK2_MAP3K3_ST	P08151	GLI1	Q99759	MAP3K3	S1078	P1077L	1077	Missense	proximal	-1	no	28.527	30.021	EPSD;PhosphoSitePlus	TCGA;COSMIC	11.002	Up-regulation
STE_STE11_MEKK2_MAP3K3_ST	P53805	RCAN1	Q99759	MAP3K3	S163	S167Y	167	Missense	distal	4	no	28.012	27.942	PhosphoSitePlus;EPSD	TCGA;COSMIC	11.002	Down-regulation
STE_STE11_MEKK2_MAP3K3_ST	P53805	RCAN1	Q99759	MAP3K3	S163	L161Q	161	Missense	proximal	-2	no	28.012	28.420	PhosphoSitePlus;EPSD	TCGA;COSMIC	11.002	Up-regulation
STE_STE11_MEKK2_MAP3K3_ST	P53805	RCAN1	Q99759	MAP3K3	S167	S167Y	167	Missense	central	0	yes	29.082	0.000	EPSD;PhosphoSitePlus	TCGA;COSMIC	11.002	Loss
STE_STE11_MEKK2_MAP3K3_ST	P53805	RCAN1	Q99759	MAP3K3	S167	L161Q	161	Missense	distal	-6	no	29.082	28.096	EPSD;PhosphoSitePlus	TCGA;COSMIC	11.002	Down-regulation
STE_STE11_MEKK2_MAP3K3_ST	P53805	RCAN1	Q99759	MAP3K3	T179	A178V	178	Missense	proximal	-1	no	11.802	11.927	EPSD	TCGA;COSMIC;GDSC	11.002	Up-regulation
STE_STE11_MEKK2_MAP3K3_ST	P53805	RCAN1	Q99759	MAP3K3	T179	A178S	178	Missense	proximal	-1	no	11.802	13.214	EPSD	TCGA;COSMIC	11.002	Up-regulation
STE_STE11_MEKK2_MAP3K3_ST	P53805	RCAN1	Q99759	MAP3K3	T179	E176G	176	Missense	distal	-3	no	11.802	13.626	EPSD	TCGA;COSMIC	11.002	Up-regulation
STE_STE11_MEKK2_MAP3K3_ST	P53805	RCAN1	Q99759	MAP3K3	T179	P180S	180	Missense	proximal	1	no	11.802	7.844	EPSD	TCGA	11.002	Loss
TKL_STKR_STKR1_TGFBR1_ST	Q03167	TGFBR3	P36897	TGFBR1	S322	I316T	316	Missense	distal	-6	no	16.194	15.476	EPSD	TCGA;ICGC;COSMIC	13.873	Down-regulation
TKL_STKR_STKR1_TGFBR1_ST	Q03167	TGFBR3	P36897	TGFBR1	S322	N326Y	326	Missense	distal	4	no	16.194	16.330	EPSD	TCGA;ICGC;COSMIC	13.873	Up-regulation
TKL_STKR_STKR1_TGFBR1_ST	Q03167	TGFBR3	P36897	TGFBR1	S651	D648H	648	Missense	distal	-3	no	14.135	14.045	EPSD	TCGA;ICGC;COSMIC	13.873	Down-regulation
TKL_STKR_STKR1_TGFBR1_ST	Q03167	TGFBR3	P36897	TGFBR1	S651	S645L	645	Missense	distal	-6	no	14.135	14.380	EPSD	TCGA;ICGC;COSMIC	13.873	Up-regulation
TKL_STKR_STKR1_TGFBR1_ST	Q03167	TGFBR3	P36897	TGFBR1	S651	R649M	649	Missense	proximal	-2	no	14.135	14.304	EPSD	TCGA;ICGC;COSMIC;CCLE	13.873	Up-regulation
TKL_STKR_STKR1_TGFBR1_ST	Q03167	TGFBR3	P36897	TGFBR1	S651	I655S	655	Missense	distal	4	no	14.135	13.984	EPSD	TCGA;ICGC;COSMIC	13.873	Down-regulation
TKL_STKR_STKR1_TGFBR1_ST	Q03167	TGFBR3	P36897	TGFBR1	S831	S832N	832	Missense	proximal	1	no	13.839	13.982	PhosphoSitePlus	TCGA;ICGC;COSMIC	13.873	Gain
TKL_STKR_STKR1_TGFBR1_ST	Q15796	SMAD2	P36897	TGFBR1	S118	R120Q	120	Missense	proximal	2	no	16.204	16.286	EPSD	TCGA;ICGC;COSMIC	13.873	Up-regulation
TKL_STKR_STKR1_TGFBR1_ST	Q15796	SMAD2	P36897	TGFBR1	S118	G122V	122	Missense	distal	4	no	16.204	16.143	EPSD	TCGA;ICGC;COSMIC	13.873	Down-regulation
TKL_STKR_STKR1_TGFBR1_ST	Q15796	SMAD2	P36897	TGFBR1	S250	S250F	250	Missense	central	0	yes	15.150	0.000	EPSD	TCGA;ICGC;COSMIC	13.873	Loss
TKL_STKR_STKR1_TGFBR1_ST	Q15796	SMAD2	P36897	TGFBR1	S260	Q264L	264	Missense	distal	4	no	14.690	14.748	EPSD	TCGA;ICGC;COSMIC	13.873	Up-regulation
TKL_STKR_STKR1_TGFBR1_ST	Q15796	SMAD2	P36897	TGFBR1	S260	D262Y	262	Missense	proximal	2	no	14.690	14.612	EPSD	TCGA;ICGC;COSMIC	13.873	Down-regulation
TKL_STKR_STKR1_TGFBR1_ST	Q15796	SMAD2	P36897	TGFBR1	S464	G457A	457	Missense	distal	-7	no	17.945	17.859	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	13.873	Down-regulation
TKL_STKR_STKR1_TGFBR1_ST	P68104	EEF1A1	P36897	TGFBR1	S175	K179T	179	Missense	distal	4	no	14.008	13.861	EPSD	TCGA;ICGC	13.873	Loss
TKL_STKR_STKR1_TGFBR1_ST	P68104	EEF1A1	P36897	TGFBR1	S354	H349Y	349	Missense	distal	-5	no	15.279	15.170	EPSD	TCGA;ICGC;COSMIC	13.873	Down-regulation
TKL_STKR_STKR1_TGFBR1_ST	P68104	EEF1A1	P36897	TGFBR1	S354	G356D	356	Missense	proximal	2	no	15.279	15.330	EPSD	TCGA;ICGC;COSMIC	13.873	Up-regulation
TKL_STKR_STKR1_TGFBR1_ST	Q9H3D4	TP63	P36897	TGFBR1	S160	P166L	166	Missense	distal	6	no	29.350	30.449	EPSD	TCGA;ICGC;COSMIC	13.873	Up-regulation
TKL_STKR_STKR1_TGFBR1_ST	Q9H3D4	TP63	P36897	TGFBR1	S160	A164T	164	Missense	distal	4	no	29.350	29.240	EPSD	TCGA;COSMIC	13.873	Down-regulation
TKL_STKR_STKR1_TGFBR1_ST	Q9H3D4	TP63	P36897	TGFBR1	S160	A164V	164	Missense	distal	4	no	29.350	29.384	EPSD	TCGA;ICGC;COSMIC	13.873	Up-regulation
TKL_STKR_STKR1_TGFBR1_ST	Q9H3D4	TP63	P36897	TGFBR1	S160	P163L	163	Missense	distal	3	no	29.350	29.082	EPSD	TCGA;ICGC;COSMIC	13.873	Down-regulation
TKL_STKR_STKR1_TGFBR1_ST	Q9H3D4	TP63	P36897	TGFBR1	S160	S153R	153	Missense	distal	-7	no	29.350	26.228	EPSD	TCGA;ICGC;COSMIC	13.873	Down-regulation
TKL_STKR_STKR1_TGFBR1_ST	Q9H3D4	TP63	P36897	TGFBR1	S160	D157Y	157	Missense	distal	-3	no	29.350	29.106	EPSD	TCGA;ICGC;COSMIC	13.873	Down-regulation
TKL_STKR_STKR1_TGFBR1_ST	Q9H3D4	TP63	P36897	TGFBR1	S162	P166L	166	Missense	distal	4	no	28.456	28.488	EPSD	TCGA;ICGC;COSMIC	13.873	Up-regulation
TKL_STKR_STKR1_TGFBR1_ST	Q9H3D4	TP63	P36897	TGFBR1	S162	A164T	164	Missense	proximal	2	no	28.456	28.447	EPSD	TCGA;COSMIC	13.873	Down-regulation
TKL_STKR_STKR1_TGFBR1_ST	Q9H3D4	TP63	P36897	TGFBR1	S162	A164V	164	Missense	proximal	2	no	28.456	28.450	EPSD	TCGA;ICGC;COSMIC	13.873	Down-regulation
TKL_STKR_STKR1_TGFBR1_ST	Q9H3D4	TP63	P36897	TGFBR1	S162	P163L	163	Missense	proximal	1	no	28.456	28.486	EPSD	TCGA;ICGC;COSMIC	13.873	Up-regulation
TKL_STKR_STKR1_TGFBR1_ST	Q9H3D4	TP63	P36897	TGFBR1	S162	D157Y	157	Missense	distal	-5	no	28.456	28.431	EPSD	TCGA;ICGC;COSMIC	13.873	Down-regulation
TKL_STKR_STKR1_TGFBR1_ST	Q9H3D4	TP63	P36897	TGFBR1	S367	K369N	369	Missense	proximal	2	no	15.787	15.815	EPSD	TCGA;COSMIC	13.873	Up-regulation
TKL_STKR_STKR1_TGFBR1_ST	Q9H3D4	TP63	P36897	TGFBR1	S367	S365L	365	Missense	proximal	-2	no	15.787	15.304	EPSD	TCGA;ICGC;COSMIC	13.873	Down-regulation
TKL_STKR_STKR1_TGFBR1_ST	Q9H3D4	TP63	P36897	TGFBR1	S455	S458L	458	Missense	distal	3	no	14.980	15.487	EPSD	TCGA;COSMIC	13.873	Up-regulation
TKL_STKR_STKR1_TGFBR1_ST	Q9H3D4	TP63	P36897	TGFBR1	S455	P456L	456	Missense	proximal	1	no	14.980	15.010	EPSD	TCGA;COSMIC	13.873	Up-regulation
TKL_STKR_STKR1_TGFBR1_ST	Q9H3D4	TP63	P36897	TGFBR1	S457	P464L	464	Missense	distal	7	no	15.283	15.840	EPSD	TCGA;COSMIC	13.873	Up-regulation
TKL_STKR_STKR1_TGFBR1_ST	Q9H3D4	TP63	P36897	TGFBR1	S457	S458L	458	Missense	proximal	1	no	15.283	15.353	EPSD	TCGA;COSMIC	13.873	Up-regulation
TKL_STKR_STKR1_TGFBR1_ST	Q9H3D4	TP63	P36897	TGFBR1	S457	P456L	456	Missense	proximal	-1	no	15.283	16.044	EPSD	TCGA;COSMIC	13.873	Up-regulation
TKL_STKR_STKR1_TGFBR1_ST	Q9H3D4	TP63	P36897	TGFBR1	S463	P464L	464	Missense	proximal	1	no	17.273	17.303	EPSD	TCGA;COSMIC	13.873	Up-regulation
TKL_STKR_STKR1_TGFBR1_ST	Q9H3D4	TP63	P36897	TGFBR1	S463	M469I	469	Missense	distal	6	no	17.273	17.915	EPSD	TCGA;COSMIC	13.873	Up-regulation
TKL_STKR_STKR1_TGFBR1_ST	Q9H3D4	TP63	P36897	TGFBR1	S463	N467S	467	Missense	distal	4	no	17.273	17.280	EPSD	TCGA;COSMIC	13.873	Up-regulation
TKL_STKR_STKR1_TGFBR1_ST	Q9H3D4	TP63	P36897	TGFBR1	S463	S458L	458	Missense	distal	-5	no	17.273	17.203	EPSD	TCGA;COSMIC	13.873	Down-regulation
TKL_STKR_STKR1_TGFBR1_ST	Q9H3D4	TP63	P36897	TGFBR1	S463	P456L	456	Missense	distal	-7	no	17.273	18.650	EPSD	TCGA;COSMIC	13.873	Up-regulation
TKL_STKR_STKR1_TGFBR1_ST	Q9H3D4	TP63	P36897	TGFBR1	S621	H615Y	615	Missense	distal	-6	no	14.117	14.155	EPSD	TCGA;COSMIC	13.873	Up-regulation
TKL_STKR_STKR1_TGFBR1_ST	P17813	ENG	P36897	TGFBR1	S646	S653F	653	Missense	distal	7	no	17.726	15.899	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	13.873	Down-regulation
TKL_STKR_STKR1_TGFBR1_ST	P17813	ENG	P36897	TGFBR1	S649	S653F	653	Missense	distal	4	no	19.642	19.778	PhosphoSitePlus;EPSD	TCGA;ICGC;COSMIC	13.873	Up-regulation
TKL_STKR_STKR1_TGFBR1_ST	Q96FW1	OTUB1	P36897	TGFBR1	S55	E50D	50	Missense	distal	-5	no	14.910	15.064	EPSD	TCGA;ICGC;COSMIC	13.873	Up-regulation
CAMK_MAPKAPK_MK5_MAPKAPK5_ST	O60229	KALRN	Q8IW41	MAPKAPK5	S86	R92H	92	Missense	distal	6	no	29.183	29.043	EPSD	TCGA;ICGC;COSMIC	23.028	Down-regulation
CAMK_MAPKAPK_MK5_MAPKAPK5_ST	O60229	KALRN	Q8IW41	MAPKAPK5	S86	C90R	90	Missense	distal	4	no	29.183	29.200	EPSD	TCGA;ICGC	23.028	Up-regulation
CAMK_MAPKAPK_MK5_MAPKAPK5_ST	O60229	KALRN	Q8IW41	MAPKAPK5	S86	C90S	90	Missense	distal	4	no	29.183	29.096	EPSD	TCGA;ICGC;COSMIC	23.028	Down-regulation
CAMK_MAPKAPK_MK5_MAPKAPK5_ST	O60229	KALRN	Q8IW41	MAPKAPK5	S86	Y80S	80	Missense	distal	-6	no	29.183	29.033	EPSD	TCGA;ICGC;COSMIC	23.028	Down-regulation
CAMK_MAPKAPK_MK5_MAPKAPK5_ST	O60229	KALRN	Q8IW41	MAPKAPK5	S487	P488S	488	Missense	proximal	1	no	48.952	48.896	PhosphoSitePlus	TCGA;ICGC;COSMIC	23.028	Down-regulation
CAMK_MAPKAPK_MK5_MAPKAPK5_ST	O60229	KALRN	Q8IW41	MAPKAPK5	S487	S491F	491	Missense	distal	4	no	48.952	49.088	PhosphoSitePlus	TCGA;ICGC;COSMIC	23.028	Up-regulation
CAMK_MAPKAPK_MK5_MAPKAPK5_ST	O60229	KALRN	Q8IW41	MAPKAPK5	S487	P488L	488	Missense	proximal	1	no	48.952	48.919	PhosphoSitePlus	TCGA;ICGC;COSMIC	23.028	Down-regulation
CAMK_MAPKAPK_MK5_MAPKAPK5_ST	O60229	KALRN	Q8IW41	MAPKAPK5	S487	S493F	493	Missense	distal	6	no	48.952	49.107	PhosphoSitePlus	TCGA;ICGC;COSMIC	23.028	Up-regulation
CAMK_MAPKAPK_MK5_MAPKAPK5_ST	O60229	KALRN	Q8IW41	MAPKAPK5	S1448	D1455N	1455	Missense	distal	7	no	24.179	24.133	EPSD	TCGA;COSMIC	23.028	Down-regulation
CAMK_MAPKAPK_MK5_MAPKAPK5_ST	O60229	KALRN	Q8IW41	MAPKAPK5	S1448	E1444K	1444	Missense	distal	-4	no	24.179	24.054	EPSD	TCGA;COSMIC	23.028	Down-regulation
CAMK_MAPKAPK_MK5_MAPKAPK5_ST	O60229	KALRN	Q8IW41	MAPKAPK5	S1448	D1441N	1441	Missense	distal	-7	no	24.179	24.628	EPSD	TCGA;ICGC;COSMIC	23.028	Up-regulation
CAMK_MAPKAPK_MK5_MAPKAPK5_ST	O60229	KALRN	Q8IW41	MAPKAPK5	S1488	R1491W	1491	Missense	distal	3	no	23.284	23.388	EPSD	TCGA;ICGC;COSMIC	23.028	Up-regulation
CAMK_MAPKAPK_MK5_MAPKAPK5_ST	O60229	KALRN	Q8IW41	MAPKAPK5	S1488	S1488L	1488	Missense	central	0	yes	23.284	0.000	EPSD	TCGA;COSMIC	23.028	Loss
CAMK_MAPKAPK_MK5_MAPKAPK5_ST	O60229	KALRN	Q8IW41	MAPKAPK5	S1488	R1494W	1494	Missense	distal	6	no	23.284	23.332	EPSD	TCGA;COSMIC;CCLE	23.028	Up-regulation
CAMK_MAPKAPK_MK5_MAPKAPK5_ST	O60229	KALRN	Q8IW41	MAPKAPK5	S1488	R1491Q	1491	Missense	distal	3	no	23.284	23.670	EPSD	TCGA;COSMIC	23.028	Up-regulation
CAMK_MAPKAPK_MK5_MAPKAPK5_ST	O60229	KALRN	Q8IW41	MAPKAPK5	S1488	R1494Q	1494	Missense	distal	6	no	23.284	23.225	EPSD	TCGA;ICGC;COSMIC	23.028	Down-regulation
CAMK_MAPKAPK_MK5_MAPKAPK5_ST	P25685	DNAJB1	Q8IW41	MAPKAPK5	S16	E18K	18	Missense	proximal	2	no	31.100	29.816	EPSD	TCGA;ICGC;COSMIC	23.028	Down-regulation
CAMK_MAPKAPK_MK5_MAPKAPK5_ST	P25685	DNAJB1	Q8IW41	MAPKAPK5	S16	E18Q	18	Missense	proximal	2	no	31.100	30.513	EPSD	TCGA;ICGC;COSMIC	23.028	Down-regulation
CAMK_MAPKAPK_MK5_MAPKAPK5_ST	P25685	DNAJB1	Q8IW41	MAPKAPK5	S151	R157G	157	Missense	distal	6	no	43.868	43.962	EPSD;PhosphoSitePlus	TCGA;COSMIC	23.028	Up-regulation
CAMK_MAPKAPK_MK5_MAPKAPK5_ST	P25685	DNAJB1	Q8IW41	MAPKAPK5	S171	L172I	172	Missense	proximal	1	no	41.324	41.130	PhosphoSitePlus;EPSD	TCGA;COSMIC	23.028	Down-regulation
CAMK_MAPKAPK_MK5_MAPKAPK5_ST	P25685	DNAJB1	Q8IW41	MAPKAPK5	S171	H166Q	166	Missense	distal	-5	no	41.324	37.060	PhosphoSitePlus;EPSD	TCGA;COSMIC	23.028	Down-regulation
CAMK_MAPKAPK_MK5_MAPKAPK5_ST	P25685	DNAJB1	Q8IW41	MAPKAPK5	S171	V164A	164	Missense	distal	-7	no	41.324	41.745	PhosphoSitePlus;EPSD	TCGA;COSMIC	23.028	Up-regulation
CAMK_MAPKAPK_MK5_MAPKAPK5_ST	P25685	DNAJB1	Q8IW41	MAPKAPK5	S171	D167H	167	Missense	distal	-4	no	41.324	41.801	PhosphoSitePlus;EPSD	TCGA;COSMIC	23.028	Up-regulation
CAMK_MAPKAPK_MK5_MAPKAPK5_ST	P25685	DNAJB1	Q8IW41	MAPKAPK5	S177	L172I	172	Missense	distal	-5	no	21.812	23.239	EPSD	TCGA;COSMIC	23.028	Gain
CAMK_MAPKAPK_MK5_MAPKAPK5_ST	P25685	DNAJB1	Q8IW41	MAPKAPK5	S196	R198Q	198	Missense	proximal	2	no	25.589	29.281	EPSD	TCGA;COSMIC	23.028	Up-regulation
CAMK_MAPKAPK_MK5_MAPKAPK5_ST	P04637	TP53	Q8IW41	MAPKAPK5	S46	D48N	48	Missense	proximal	2	no	26.832	27.826	EPSD	TCGA;ICGC;COSMIC;GDSC;CCLE	23.028	Up-regulation
CAMK_MAPKAPK_MK5_MAPKAPK5_ST	P04637	TP53	Q8IW41	MAPKAPK5	S127	Y126C	126	Missense	proximal	-1	no	22.875	31.340	EPSD	TCGA;ICGC;COSMIC;GDSC	23.028	Gain
CAMK_MAPKAPK_MK5_MAPKAPK5_ST	P04637	TP53	Q8IW41	MAPKAPK5	S127	F134V	134	Missense	distal	7	no	22.875	23.029	EPSD	TCGA;ICGC;COSMIC	23.028	Gain
CAMK_MAPKAPK_MK5_MAPKAPK5_ST	P04637	TP53	Q8IW41	MAPKAPK5	S127	K120E	120	Missense	distal	-7	no	22.875	23.448	EPSD	TCGA;ICGC;COSMIC	23.028	Gain
CAMK_MAPKAPK_MK5_MAPKAPK5_ST	P04637	TP53	Q8IW41	MAPKAPK5	S127	Y126H	126	Missense	proximal	-1	no	22.875	26.519	EPSD	TCGA;ICGC;COSMIC;GDSC	23.028	Gain
CAMK_MAPKAPK_MK5_MAPKAPK5_ST	P04637	TP53	Q8IW41	MAPKAPK5	S269	G266R	266	Missense	distal	-3	no	2.078	23.194	EPSD	TCGA;ICGC;COSMIC;GDSC;CCLE	23.028	Gain
CAMK_MAPKAPK_MK5_MAPKAPK5_ST	P04637	TP53	Q8IW41	MAPKAPK5	S362	A355T	355	Missense	distal	-7	no	29.531	29.220	EPSD	TCGA;ICGC;COSMIC	23.028	Down-regulation
CAMK_MAPKAPK_MK5_MAPKAPK5_ST	P04637	TP53	Q8IW41	MAPKAPK5	S371	S376C	376	Missense	distal	5	no	24.928	21.221	EPSD	TCGA;ICGC;COSMIC	23.028	Loss
CAMK_MAPKAPK_MK5_MAPKAPK5_ST	P04637	TP53	Q8IW41	MAPKAPK5	S371	Q375K	375	Missense	distal	4	no	24.928	24.929	EPSD	TCGA;ICGC;COSMIC	23.028	Up-regulation
CAMK_MAPKAPK_MK5_MAPKAPK5_ST	Q15382	RHEB	Q8IW41	MAPKAPK5	S130	V128E	128	Missense	proximal	-2	no	43.637	43.760	PhosphoSitePlus	TCGA;ICGC;COSMIC	23.028	Up-regulation
CAMK_MAPKAPK_MK5_MAPKAPK5_ST	Q15382	RHEB	Q8IW41	MAPKAPK5	S130	L137F	137	Missense	distal	7	no	43.637	43.672	PhosphoSitePlus	TCGA;COSMIC	23.028	Up-regulation
CAMK_MAPKAPK_MK5_MAPKAPK5_ST	P07101	TH	Q8IW41	MAPKAPK5	S19	A23T	23	Missense	distal	4	no	38.309	38.366	PhosphoSitePlus;EPSD	TCGA;ICGC;COSMIC	23.028	Up-regulation
CAMK_MAPKAPK_MK5_MAPKAPK5_ST	P07101	TH	Q8IW41	MAPKAPK5	S19	R15H	15	Missense	distal	-4	no	38.309	38.706	PhosphoSitePlus;EPSD	TCGA;ICGC;COSMIC;GDSC	23.028	Up-regulation
CAMK_MAPKAPK_MK5_MAPKAPK5_ST	P07101	TH	Q8IW41	MAPKAPK5	S71	R64W	64	Missense	distal	-7	no	38.327	38.934	EPSD	TCGA;COSMIC	23.028	Up-regulation
CAMK_MAPKAPK_MK5_MAPKAPK5_ST	P07101	TH	Q8IW41	MAPKAPK5	S71	K78N	78	Missense	distal	7	no	38.327	38.424	EPSD	TCGA;COSMIC	23.028	Up-regulation
CAMK_MAPKAPK_MK5_MAPKAPK5_ST	P07101	TH	Q8IW41	MAPKAPK5	S435	E436K	436	Missense	proximal	1	no	41.810	41.750	EPSD	TCGA;COSMIC	23.028	Down-regulation
CAMK_MAPKAPK_MK5_MAPKAPK5_ST	P07101	TH	Q8IW41	MAPKAPK5	S435	R441P	441	Missense	distal	6	no	41.810	41.770	EPSD	TCGA;COSMIC	23.028	Down-regulation
CAMK_MAPKAPK_MK5_MAPKAPK5_ST	P07101	TH	Q8IW41	MAPKAPK5	S435	G428R	428	Missense	distal	-7	no	41.810	40.610	EPSD	TCGA;COSMIC	23.028	Down-regulation
CAMK_DAPK_DAPK_DAPK2_ST	Q9UIK4	DAPK2	Q9UIK4	DAPK2	T275	E269D	269	Missense	distal	-6	no	3.511	3.547	EPSD	TCGA;ICGC;COSMIC	1.958	Up-regulation
CAMK_DAPK_DAPK_DAPK2_ST	Q9UIK4	DAPK2	Q9UIK4	DAPK2	T275	E278V	278	Missense	distal	3	no	3.511	3.454	EPSD	TCGA;ICGC;COSMIC	1.958	Down-regulation
CAMK_DAPK_DAPK_DAPK2_ST	Q9UIK4	DAPK2	Q9UIK4	DAPK2	S318	R313S	313	Missense	distal	-5	no	5.663	4.437	PhosphoSitePlus	TCGA;ICGC;COSMIC	1.958	Down-regulation
CAMK_DAPK_DAPK_DAPK2_ST	Q9UIK4	DAPK2	Q9UIK4	DAPK2	S318	W315R	315	Missense	distal	-3	no	5.663	6.262	PhosphoSitePlus	TCGA;ICGC;COSMIC	1.958	Up-regulation
CAMK_DAPK_DAPK_DAPK2_ST	Q9UIK4	DAPK2	Q9UIK4	DAPK2	S320	R313S	313	Missense	distal	-7	no	2.303	2.418	EPSD	TCGA;ICGC;COSMIC	1.958	Up-regulation
CAMK_DAPK_DAPK_DAPK2_ST	Q9UIK4	DAPK2	Q9UIK4	DAPK2	S320	W315R	315	Missense	distal	-5	no	2.303	3.290	EPSD	TCGA;ICGC;COSMIC	1.958	Up-regulation
CAMK_DAPK_DAPK_DAPK2_ST	Q9UIK4	DAPK2	Q9UIK4	DAPK2	S320	H327N	327	Missense	distal	7	no	2.303	2.304	EPSD	TCGA;ICGC;COSMIC	1.958	Up-regulation
CAMK_DAPK_DAPK_DAPK2_ST	Q9UIK4	DAPK2	Q9UIK4	DAPK2	S367	P363S	363	Missense	distal	-4	no	3.511	3.285	EPSD	TCGA;ICGC;COSMIC	1.958	Down-regulation
CAMK_DAPK_DAPK_DAPK2_ST	Q9UIK4	DAPK2	Q9UIK4	DAPK2	S367	R366K	366	Missense	proximal	-1	no	3.511	3.512	EPSD	TCGA;ICGC;COSMIC	1.958	Up-regulation
CAMK_DAPK_DAPK_DAPK2_ST	Q9UIK4	DAPK2	Q9UIK4	DAPK2	S367	R365K	365	Missense	proximal	-2	no	3.511	3.496	EPSD	TCGA;ICGC;COSMIC	1.958	Down-regulation
CAMK_DAPK_DAPK_DAPK2_ST	Q9UIK4	DAPK2	Q9UIK4	DAPK2	T369	P363S	363	Missense	distal	-6	no	2.002	2.184	EPSD	TCGA;ICGC;COSMIC	1.958	Up-regulation
CAMK_DAPK_DAPK_DAPK2_ST	Q9UIK4	DAPK2	Q9UIK4	DAPK2	T369	R366K	366	Missense	distal	-3	no	2.002	1.993	EPSD	TCGA;ICGC;COSMIC	1.958	Down-regulation
CAMK_DAPK_DAPK_DAPK2_ST	Q9UIK4	DAPK2	Q9UIK4	DAPK2	T369	R365K	365	Missense	distal	-4	no	2.002	2.109	EPSD	TCGA;ICGC;COSMIC	1.958	Up-regulation
CAMK_DAPK_DAPK_DAPK2_ST	Q8N122	RPTOR	Q9UIK4	DAPK2	S721	S719F	719	Missense	proximal	-2	no	2.232	2.224	PhosphoSitePlus	TCGA;ICGC;COSMIC	1.958	Down-regulation
CAMK_DAPK_DAPK_DAPK2_ST	Q8N122	RPTOR	Q9UIK4	DAPK2	S721	Y723C	723	Missense	proximal	2	no	2.232	2.203	PhosphoSitePlus	TCGA;COSMIC	1.958	Down-regulation
CAMK_DAPK_DAPK_DAPK2_ST	Q8N122	RPTOR	Q9UIK4	DAPK2	S721	G724E	724	Missense	distal	3	no	2.232	2.203	PhosphoSitePlus	TCGA;COSMIC	1.958	Down-regulation
CAMK_DAPK_DAPK_DAPK2_ST	Q8N122	RPTOR	Q9UIK4	DAPK2	T731	G724E	724	Missense	distal	-7	no	2.877	2.846	EPSD	TCGA;COSMIC	1.958	Down-regulation
CAMK_DAPK_DAPK_DAPK2_ST	Q8N122	RPTOR	Q9UIK4	DAPK2	S854	T857M	857	Missense	distal	3	no	2.343	2.372	EPSD	TCGA;COSMIC	1.958	Up-regulation
CAMK_DAPK_DAPK_DAPK2_ST	Q8N122	RPTOR	Q9UIK4	DAPK2	T857	T857M	857	Missense	central	0	yes	2.033	0.000	EPSD	TCGA;COSMIC	1.958	Loss
AGC_PKC_PKCh_PRKCH_ST	P05107	ITGB2	P24723	PRKCH	T118	A112S	112	Missense	distal	-6	no	24.636	22.195	EPSD	TCGA;ICGC;COSMIC	22.099	Down-regulation
AGC_PKC_PKCh_PRKCH_ST	P05107	ITGB2	P24723	PRKCH	T118	R121Q	121	Missense	distal	3	no	24.636	24.885	EPSD	TCGA;ICGC;COSMIC	22.099	Up-regulation
AGC_PKC_PKCh_PRKCH_ST	P05107	ITGB2	P24723	PRKCH	T118	R121W	121	Missense	distal	3	no	24.636	25.216	EPSD	TCGA;ICGC;COSMIC	22.099	Up-regulation
AGC_PKC_PKCh_PRKCH_ST	P05107	ITGB2	P24723	PRKCH	T118	R120W	120	Missense	proximal	2	no	24.636	23.013	EPSD	TCGA;ICGC	22.099	Down-regulation
AGC_PKC_PKCh_PRKCH_ST	P05107	ITGB2	P24723	PRKCH	S591	R587C	587	Missense	distal	-4	no	25.310	24.728	EPSD	TCGA;ICGC;COSMIC	22.099	Down-regulation
AGC_PKC_PKCh_PRKCH_ST	P05107	ITGB2	P24723	PRKCH	S591	R586Q	586	Missense	distal	-5	no	25.310	24.226	EPSD	TCGA;ICGC;COSMIC	22.099	Down-regulation
AGC_PKC_PKCh_PRKCH_ST	P05107	ITGB2	P24723	PRKCH	S591	G594D	594	Missense	distal	3	no	25.310	25.673	EPSD	TCGA;ICGC;COSMIC	22.099	Up-regulation
AGC_PKC_PKCh_PRKCH_ST	P05107	ITGB2	P24723	PRKCH	S591	R597H	597	Missense	distal	6	no	25.310	25.610	EPSD	TCGA;ICGC;COSMIC	22.099	Up-regulation
AGC_PKC_PKCh_PRKCH_ST	P05107	ITGB2	P24723	PRKCH	S745	L743R	743	Missense	proximal	-2	no	37.899	44.292	PhosphoSitePlus;EPSD	TCGA;ICGC;COSMIC	22.099	Up-regulation
AGC_PKC_PKCh_PRKCH_ST	P05107	ITGB2	P24723	PRKCH	S745	W747L	747	Missense	proximal	2	no	37.899	38.355	PhosphoSitePlus;EPSD	TCGA;ICGC;COSMIC	22.099	Up-regulation
AGC_PKC_PKCh_PRKCH_ST	P05107	ITGB2	P24723	PRKCH	T758	A757T	757	Missense	proximal	-1	no	30.507	30.289	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	22.099	Down-regulation
AGC_PKC_PKCh_PRKCH_ST	P05107	ITGB2	P24723	PRKCH	T758	P764L	764	Missense	distal	6	no	30.507	29.434	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	22.099	Down-regulation
AGC_PKC_PKCh_PRKCH_ST	Q06124	PTPN11	P24723	PRKCH	S28	P33L	33	Missense	distal	5	no	23.957	23.034	EPSD	TCGA;ICGC;COSMIC	22.099	Down-regulation
AGC_PKC_PKCh_PRKCH_ST	Q06124	PTPN11	P24723	PRKCH	S28	S28R	28	Missense	central	0	yes	23.957	0.000	EPSD	TCGA;ICGC	22.099	Loss
AGC_PKC_PKCh_PRKCH_ST	Q06124	PTPN11	P24723	PRKCH	S34	P33L	33	Missense	proximal	-1	no	21.799	22.680	EPSD	TCGA;ICGC;COSMIC	22.099	Gain
AGC_PKC_PKCh_PRKCH_ST	Q06124	PTPN11	P24723	PRKCH	S34	S28R	28	Missense	distal	-6	no	21.799	27.141	EPSD	TCGA;ICGC	22.099	Gain
AGC_PKC_PKCh_PRKCH_ST	Q06124	PTPN11	P24723	PRKCH	S140	L136H	136	Missense	distal	-4	no	25.170	25.215	EPSD	TCGA;ICGC;COSMIC	22.099	Up-regulation
AGC_PKC_PKCh_PRKCH_ST	Q06124	PTPN11	P24723	PRKCH	S140	S142N	142	Missense	proximal	2	no	25.170	26.683	EPSD	TCGA;ICGC;COSMIC;GDSC;CCLE	22.099	Up-regulation
AGC_PKC_PKCh_PRKCH_ST	Q06124	PTPN11	P24723	PRKCH	S140	D146Y	146	Missense	distal	6	no	25.170	24.504	EPSD	TCGA;ICGC;COSMIC	22.099	Down-regulation
AGC_PKC_PKCh_PRKCH_ST	Q06124	PTPN11	P24723	PRKCH	S160	D155N	155	Missense	distal	-5	no	23.396	23.581	EPSD	TCGA;ICGC;COSMIC	22.099	Up-regulation
AGC_PKC_PKCh_PRKCH_ST	Q06124	PTPN11	P24723	PRKCH	S160	D156N	156	Missense	distal	-4	no	23.396	23.321	EPSD	TCGA;ICGC;COSMIC	22.099	Down-regulation
AGC_PKC_PKCh_PRKCH_ST	Q06124	PTPN11	P24723	PRKCH	S160	G163D	163	Missense	distal	3	no	23.396	23.760	EPSD	TCGA;ICGC;COSMIC	22.099	Up-regulation
AGC_PKC_PKCh_PRKCH_ST	Q06124	PTPN11	P24723	PRKCH	S503	Q510L	510	Missense	distal	7	no	23.882	24.815	EPSD	TCGA;ICGC;COSMIC	22.099	Up-regulation
AGC_PKC_PKCh_PRKCH_ST	Q06124	PTPN11	P24723	PRKCH	S503	Q510H	510	Missense	distal	7	no	23.882	22.862	EPSD	TCGA;ICGC;COSMIC;GDSC;CCLE	22.099	Down-regulation
AGC_PKC_PKCh_PRKCH_ST	P49841	GSK3B	P24723	PRKCH	S21	Q19R	19	Missense	proximal	-2	no	23.547	28.056	EPSD	TCGA	22.099	Up-regulation
AGC_PKC_PKCh_PRKCH_ST	P49841	GSK3B	P24723	PRKCH	S21	S25N	25	Missense	distal	4	no	23.547	21.048	EPSD	TCGA;ICGC	22.099	Loss
AGC_PKC_PKCh_PRKCH_ST	P49841	GSK3B	P24723	PRKCH	S21	A22S	22	Missense	proximal	1	no	23.547	20.342	EPSD	TCGA;ICGC	22.099	Loss
AGC_PKC_PKCh_PRKCH_ST	P49841	GSK3B	P24723	PRKCH	S29	A22S	22	Missense	distal	-7	no	21.727	22.567	EPSD	TCGA;ICGC	22.099	Gain
AGC_PKC_PKCh_PRKCH_ST	P49841	GSK3B	P24723	PRKCH	S55	T59I	59	Missense	distal	4	no	23.298	23.036	EPSD	TCGA;ICGC;COSMIC	22.099	Down-regulation
AGC_PKC_PKCh_PRKCH_ST	P49841	GSK3B	P24723	PRKCH	S55	D49N	49	Missense	distal	-6	no	23.298	24.617	EPSD	TCGA;ICGC;COSMIC	22.099	Up-regulation
AGC_PKC_PKCh_PRKCH_ST	P49841	GSK3B	P24723	PRKCH	S215	Y216C	216	Missense	proximal	1	no	24.060	21.860	EPSD	TCGA;ICGC;COSMIC	22.099	Loss
AGC_PKC_PKCh_PRKCH_ST	P49841	GSK3B	P24723	PRKCH	S215	S215L	215	Missense	central	0	yes	24.060	0.000	EPSD	TCGA;ICGC;COSMIC	22.099	Loss
AGC_PKC_PKCh_PRKCH_ST	Q15139	PRKD1	P24723	PRKCH	T217	S223C	223	Missense	distal	6	no	19.716	22.263	EPSD	TCGA;ICGC;COSMIC	22.099	Gain
AGC_PKC_PKCh_PRKCH_ST	Q15139	PRKD1	P24723	PRKCH	S223	S223C	223	Missense	central	0	yes	23.139	0.000	EPSD	TCGA;ICGC;COSMIC	22.099	Loss
AGC_PKC_PKCh_PRKCH_ST	Q15139	PRKD1	P24723	PRKCH	S223	R216C	216	Missense	distal	-7	no	23.139	22.355	EPSD	TCGA;ICGC;COSMIC	22.099	Down-regulation
AGC_PKC_PKCh_PRKCH_ST	Q15139	PRKD1	P24723	PRKCH	S223	E229K	229	Missense	distal	6	no	23.139	24.432	EPSD	TCGA;ICGC;COSMIC	22.099	Up-regulation
AGC_PKC_PKCh_PRKCH_ST	Q15139	PRKD1	P24723	PRKCH	S223	D228N	228	Missense	distal	5	no	23.139	22.290	EPSD	TCGA;ICGC;COSMIC	22.099	Down-regulation
AGC_PKC_PKCh_PRKCH_ST	Q15139	PRKD1	P24723	PRKCH	T224	S223C	223	Missense	proximal	-1	no	23.132	22.643	EPSD	TCGA;ICGC;COSMIC	22.099	Down-regulation
AGC_PKC_PKCh_PRKCH_ST	Q15139	PRKD1	P24723	PRKCH	T224	L231F	231	Missense	distal	7	no	23.132	21.918	EPSD	TCGA;ICGC;COSMIC	22.099	Loss
AGC_PKC_PKCh_PRKCH_ST	Q15139	PRKD1	P24723	PRKCH	T224	E229K	229	Missense	distal	5	no	23.132	23.114	EPSD	TCGA;ICGC;COSMIC	22.099	Down-regulation
AGC_PKC_PKCh_PRKCH_ST	Q15139	PRKD1	P24723	PRKCH	T224	D228N	228	Missense	distal	4	no	23.132	23.054	EPSD	TCGA;ICGC;COSMIC	22.099	Down-regulation
AGC_PKC_PKCh_PRKCH_ST	Q15139	PRKD1	P24723	PRKCH	S379	M372I	372	Missense	distal	-7	no	23.225	21.808	EPSD	TCGA;ICGC;COSMIC	22.099	Loss
AGC_PKC_PKCh_PRKCH_ST	Q15139	PRKD1	P24723	PRKCH	S379	Q383R	383	Missense	distal	4	no	23.225	20.725	EPSD	TCGA;COSMIC	22.099	Loss
AGC_PKC_PKCh_PRKCH_ST	Q15139	PRKD1	P24723	PRKCH	S379	D378N	378	Missense	proximal	-1	no	23.225	23.124	EPSD	TCGA;COSMIC	22.099	Down-regulation
AGC_PKC_PKCh_PRKCH_ST	Q15139	PRKD1	P24723	PRKCH	S379	M382I	382	Missense	distal	3	no	23.225	23.209	EPSD	TCGA;ICGC	22.099	Down-regulation
AGC_PKC_PKCh_PRKCH_ST	Q15139	PRKD1	P24723	PRKCH	S397	P398L	398	Missense	proximal	1	no	11.615	23.025	EPSD	TCGA;COSMIC	22.099	Gain
AGC_PKC_PKCh_PRKCH_ST	Q15139	PRKD1	P24723	PRKCH	T422	M429T	429	Missense	distal	7	no	23.621	23.950	EPSD	TCGA	22.099	Up-regulation
AGC_PKC_PKCh_PRKCH_ST	Q15139	PRKD1	P24723	PRKCH	S738	R740Q	740	Missense	proximal	2	no	42.688	41.483	PhosphoSitePlus;EPSD	TCGA;ICGC;COSMIC	22.099	Down-regulation
AGC_PKC_PKCh_PRKCH_ST	Q15139	PRKD1	P24723	PRKCH	S738	R732Q	732	Missense	distal	-6	no	42.688	39.307	PhosphoSitePlus;EPSD	TCGA;COSMIC	22.099	Down-regulation
AGC_PKC_PKCh_PRKCH_ST	Q15139	PRKD1	P24723	PRKCH	S738	R732L	732	Missense	distal	-6	no	42.688	39.394	PhosphoSitePlus;EPSD	TCGA;COSMIC	22.099	Down-regulation
AGC_PKC_PKCh_PRKCH_ST	Q15139	PRKD1	P24723	PRKCH	S738	R732W	732	Missense	distal	-6	no	42.688	39.092	PhosphoSitePlus;EPSD	TCGA;COSMIC	22.099	Down-regulation
AGC_PKC_PKCh_PRKCH_ST	Q15139	PRKD1	P24723	PRKCH	S742	R740Q	740	Missense	proximal	-2	no	43.278	38.769	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	22.099	Down-regulation
AGC_PKC_PKCh_PRKCH_ST	Q15139	PRKD1	P24723	PRKCH	S742	P747T	747	Missense	distal	5	no	43.278	41.284	EPSD;PhosphoSitePlus	TCGA;COSMIC	22.099	Down-regulation
AGC_PKC_PKCh_PRKCH_ST	Q15139	PRKD1	P24723	PRKCH	S742	A748S	748	Missense	distal	6	no	43.278	42.891	EPSD;PhosphoSitePlus	TCGA;COSMIC	22.099	Down-regulation
AGC_PKC_PKCh_PRKCH_ST	Q15139	PRKD1	P24723	PRKCH	S742	T746A	746	Missense	distal	4	no	43.278	42.939	EPSD;PhosphoSitePlus	TCGA	22.099	Down-regulation
AGC_PKC_PKCh_PRKCH_ST	Q9BZL6	PRKD2	P24723	PRKCH	T276	R274Q	274	Missense	proximal	-2	no	22.532	18.023	EPSD	TCGA;COSMIC	22.099	Loss
AGC_PKC_PKCh_PRKCH_ST	Q9BZL6	PRKD2	P24723	PRKCH	T276	I269V	269	Missense	distal	-7	no	22.532	23.454	EPSD	TCGA;COSMIC	22.099	Up-regulation
AGC_PKC_PKCh_PRKCH_ST	Q9BZL6	PRKD2	P24723	PRKCH	S362	E363K	363	Missense	proximal	1	no	23.520	25.073	EPSD	TCGA;COSMIC	22.099	Up-regulation
AGC_PKC_PKCh_PRKCH_ST	Q9BZL6	PRKD2	P24723	PRKCH	S362	E356G	356	Missense	distal	-6	no	23.520	22.278	EPSD	TCGA;COSMIC	22.099	Down-regulation
AGC_PKC_PKCh_PRKCH_ST	Q9BZL6	PRKD2	P24723	PRKCH	T391	R393W	393	Missense	proximal	2	no	27.000	25.377	EPSD	TCGA;COSMIC	22.099	Down-regulation
AGC_PKC_PKCh_PRKCH_ST	Q9BZL6	PRKD2	P24723	PRKCH	T397	R393W	393	Missense	distal	-4	no	25.216	24.677	EPSD	TCGA;COSMIC	22.099	Down-regulation
AGC_PKC_PKCh_PRKCH_ST	Q9BZL6	PRKD2	P24723	PRKCH	T433	F429L	429	Missense	distal	-4	no	22.862	22.839	EPSD	TCGA;COSMIC	22.099	Down-regulation
AGC_PKC_PKCh_PRKCH_ST	Q9BZL6	PRKD2	P24723	PRKCH	S529	S529F	529	Missense	central	0	yes	24.008	0.000	EPSD	TCGA;COSMIC	22.099	Loss
AGC_PKC_PKCh_PRKCH_ST	Q9BZL6	PRKD2	P24723	PRKCH	S706	R709H	709	Missense	distal	3	no	43.845	43.933	EPSD;PhosphoSitePlus	TCGA;COSMIC	22.099	Up-regulation
AGC_PKC_PKCh_PRKCH_ST	Q9BZL6	PRKD2	P24723	PRKCH	S706	S706L	706	Missense	central	0	yes	43.845	0.000	EPSD;PhosphoSitePlus	TCGA;COSMIC	22.099	Loss
AGC_PKC_PKCh_PRKCH_ST	Q9BZL6	PRKD2	P24723	PRKCH	S710	A716T	716	Missense	distal	6	no	43.969	42.889	EPSD;PhosphoSitePlus	TCGA;COSMIC	22.099	Down-regulation
AGC_PKC_PKCh_PRKCH_ST	Q9BZL6	PRKD2	P24723	PRKCH	S710	R709H	709	Missense	proximal	-1	no	43.969	43.674	EPSD;PhosphoSitePlus	TCGA;COSMIC	22.099	Down-regulation
AGC_PKC_PKCh_PRKCH_ST	Q9BZL6	PRKD2	P24723	PRKCH	S710	S706L	706	Missense	distal	-4	no	43.969	44.251	EPSD;PhosphoSitePlus	TCGA;COSMIC	22.099	Up-regulation
AGC_PKC_PKCh_PRKCH_ST	Q9BZL6	PRKD2	P24723	PRKCH	S710	P715S	715	Missense	distal	5	no	43.969	42.318	EPSD;PhosphoSitePlus	TCGA;COSMIC	22.099	Down-regulation
AGC_PKC_PKCh_PRKCH_ST	Q9BZL6	PRKD2	P24723	PRKCH	S797	R793H	793	Missense	distal	-4	no	21.947	22.135	EPSD	TCGA;COSMIC	22.099	Gain
AGC_PKC_PKCh_PRKCH_ST	Q9BZL6	PRKD2	P24723	PRKCH	S797	S803G	803	Missense	distal	6	no	21.947	22.718	EPSD	TCGA;COSMIC	22.099	Gain
AGC_PKC_PKCh_PRKCH_ST	Q9BZL6	PRKD2	P24723	PRKCH	S876	R874H	874	Missense	proximal	-2	no	36.640	34.550	PhosphoSitePlus;EPSD	TCGA;COSMIC	22.099	Down-regulation
AGC_PKC_PKCh_PRKCH_ST	Q9BZL6	PRKD2	P24723	PRKCH	S876	R874C	874	Missense	proximal	-2	no	36.640	29.184	PhosphoSitePlus;EPSD	TCGA;COSMIC;GDSC;CCLE	22.099	Down-regulation
AGC_PKC_PKCh_PRKCH_ST	P09211	GSTP1	P24723	PRKCH	S43	Y50H	50	Missense	distal	7	no	41.730	40.348	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	22.099	Down-regulation
AGC_PKC_PKCh_PRKCH_ST	P09211	GSTP1	P24723	PRKCH	S185	R183P	183	Missense	proximal	-2	no	39.461	34.843	PhosphoSitePlus;EPSD	TCGA;ICGC;COSMIC	22.099	Down-regulation
AGC_PKC_PKCh_PRKCH_ST	P09211	GSTP1	P24723	PRKCH	S185	R183H	183	Missense	proximal	-2	no	39.461	37.371	PhosphoSitePlus;EPSD	TCGA;ICGC;COSMIC	22.099	Down-regulation
AGC_PKC_PKCh_PRKCH_ST	P09211	GSTP1	P24723	PRKCH	S185	S178L	178	Missense	distal	-7	no	39.461	39.523	PhosphoSitePlus;EPSD	TCGA;ICGC;COSMIC	22.099	Up-regulation
AGC_PKC_PKCh_PRKCH_ST	P09211	GSTP1	P24723	PRKCH	S185	R183C	183	Missense	proximal	-2	no	39.461	32.004	PhosphoSitePlus;EPSD	TCGA;ICGC	22.099	Down-regulation
AGC_PKC_PKCh_PRKCH_ST	P49840	GSK3A	P24723	PRKCH	S401	R407Q	407	Missense	distal	6	no	24.798	24.633	EPSD	TCGA;ICGC;COSMIC	22.099	Down-regulation
Other_PLK_PLK1_PLK1_ST	Q14203	DCTN1	P53350	PLK1	S19	A20V	20	Missense	proximal	1	no	9.924	11.362	EPSD	TCGA;ICGC;COSMIC	10.919	Gain
Other_PLK_PLK1_PLK1_ST	Q14203	DCTN1	P53350	PLK1	S23	L27M	27	Missense	distal	4	no	11.515	11.179	EPSD	TCGA;ICGC;COSMIC	10.919	Down-regulation
Other_PLK_PLK1_PLK1_ST	Q14203	DCTN1	P53350	PLK1	S23	A20V	20	Missense	distal	-3	no	11.515	11.117	EPSD	TCGA;ICGC;COSMIC	10.919	Down-regulation
Other_PLK_PLK1_PLK1_ST	Q14203	DCTN1	P53350	PLK1	S111	D110Y	110	Missense	proximal	-1	no	11.527	11.070	EPSD	TCGA;ICGC;COSMIC	10.919	Down-regulation
Other_PLK_PLK1_PLK1_ST	Q14203	DCTN1	P53350	PLK1	S111	P106L	106	Missense	distal	-5	no	11.527	11.928	EPSD	TCGA;COSMIC	10.919	Up-regulation
Other_PLK_PLK1_PLK1_ST	Q14203	DCTN1	P53350	PLK1	S179	P186T	186	Missense	distal	7	no	14.194	14.152	PhosphoSitePlus	TCGA;COSMIC	10.919	Down-regulation
Other_PLK_PLK1_PLK1_ST	Q14203	DCTN1	P53350	PLK1	S179	E182K	182	Missense	distal	3	no	14.194	13.988	PhosphoSitePlus	TCGA;COSMIC	10.919	Down-regulation
Other_PLK_PLK1_PLK1_ST	Q14203	DCTN1	P53350	PLK1	S179	S180N	180	Missense	proximal	1	no	14.194	14.934	PhosphoSitePlus	TCGA;COSMIC	10.919	Up-regulation
Other_PLK_PLK1_PLK1_ST	Q14203	DCTN1	P53350	PLK1	T336	R331W	331	Missense	distal	-5	no	13.074	12.842	EPSD	TCGA	10.919	Down-regulation
Other_PLK_PLK1_PLK1_ST	Q14203	DCTN1	P53350	PLK1	T336	R331Q	331	Missense	distal	-5	no	13.074	12.335	EPSD	TCGA;COSMIC	10.919	Down-regulation
Other_PLK_PLK1_PLK1_ST	Q14203	DCTN1	P53350	PLK1	S417	E415D	415	Missense	proximal	-2	no	10.563	10.956	EPSD	TCGA;COSMIC	10.919	Gain
Other_PLK_PLK1_PLK1_ST	Q14203	DCTN1	P53350	PLK1	S541	E543D	543	Missense	proximal	2	no	11.150	11.741	EPSD	TCGA;COSMIC	10.919	Up-regulation
Other_PLK_PLK1_PLK1_ST	Q14203	DCTN1	P53350	PLK1	S595	R598W	598	Missense	distal	3	no	11.237	11.008	EPSD	TCGA;COSMIC;GDSC;CCLE	10.919	Down-regulation
Other_PLK_PLK1_PLK1_ST	Q14203	DCTN1	P53350	PLK1	S595	R598Q	598	Missense	distal	3	no	11.237	11.433	EPSD	TCGA;COSMIC	10.919	Up-regulation
Other_PLK_PLK1_PLK1_ST	Q14203	DCTN1	P53350	PLK1	S595	G600C	600	Missense	distal	5	no	11.237	11.183	EPSD	TCGA	10.919	Down-regulation
Other_PLK_PLK1_PLK1_ST	Q14203	DCTN1	P53350	PLK1	S974	R972W	972	Missense	proximal	-2	no	12.138	5.480	EPSD	TCGA;COSMIC	10.919	Loss
Other_PLK_PLK1_PLK1_ST	Q14203	DCTN1	P53350	PLK1	S974	R972Q	972	Missense	proximal	-2	no	12.138	11.963	EPSD	TCGA;COSMIC	10.919	Down-regulation
Other_PLK_PLK1_PLK1_ST	Q14203	DCTN1	P53350	PLK1	S974	E968G	968	Missense	distal	-6	no	12.138	11.473	EPSD	TCGA	10.919	Down-regulation
Other_PLK_PLK1_PLK1_ST	Q14203	DCTN1	P53350	PLK1	S974	K978N	978	Missense	distal	4	no	12.138	12.287	EPSD	TCGA	10.919	Up-regulation
Other_PLK_PLK1_PLK1_ST	Q14203	DCTN1	P53350	PLK1	S1153	K1151E	1151	Missense	proximal	-2	no	8.809	11.687	EPSD	TCGA;COSMIC	10.919	Gain
Other_PLK_PLK1_PLK1_ST	Q14203	DCTN1	P53350	PLK1	T1158	Q1161E	1161	Missense	distal	3	no	11.016	11.124	EPSD	TCGA;COSMIC	10.919	Up-regulation
Other_PLK_PLK1_PLK1_ST	Q14203	DCTN1	P53350	PLK1	T1158	Q1154H	1154	Missense	distal	-4	no	11.016	11.029	EPSD	TCGA;COSMIC	10.919	Up-regulation
Other_PLK_PLK1_PLK1_ST	Q14203	DCTN1	P53350	PLK1	T1158	Q1154L	1154	Missense	distal	-4	no	11.016	11.101	EPSD	TCGA;COSMIC	10.919	Up-regulation
Other_PLK_PLK1_PLK1_ST	Q14203	DCTN1	P53350	PLK1	T1158	K1151E	1151	Missense	distal	-7	no	11.016	11.320	EPSD	TCGA;COSMIC	10.919	Up-regulation
Other_PLK_PLK1_PLK1_ST	Q14203	DCTN1	P53350	PLK1	T1158	T1164S	1164	Missense	distal	6	no	11.016	10.740	EPSD	TCGA;COSMIC	10.919	Loss
Other_PLK_PLK1_PLK1_ST	O60563	CCNT1	P53350	PLK1	S22	R25H	25	Missense	distal	3	no	12.291	12.422	EPSD	TCGA;ICGC;COSMIC	10.919	Up-regulation
Other_PLK_PLK1_PLK1_ST	O60563	CCNT1	P53350	PLK1	S22	R16G	16	Missense	distal	-6	no	12.291	12.192	EPSD	TCGA;ICGC;COSMIC	10.919	Down-regulation
Other_PLK_PLK1_PLK1_ST	O60563	CCNT1	P53350	PLK1	S22	N21K	21	Missense	proximal	-1	no	12.291	11.857	EPSD	TCGA;ICGC;COSMIC	10.919	Down-regulation
Other_PLK_PLK1_PLK1_ST	O60563	CCNT1	P53350	PLK1	T278	R272Q	272	Missense	distal	-6	no	11.485	11.933	EPSD	TCGA;ICGC;COSMIC	10.919	Up-regulation
Other_PLK_PLK1_PLK1_ST	O60563	CCNT1	P53350	PLK1	T278	K277N	277	Missense	proximal	-1	no	11.485	11.920	EPSD	TCGA;ICGC;COSMIC	10.919	Up-regulation
Other_PLK_PLK1_PLK1_ST	O60563	CCNT1	P53350	PLK1	T278	D271E	271	Missense	distal	-7	no	11.485	11.774	EPSD	TCGA;ICGC;COSMIC	10.919	Up-regulation
Other_PLK_PLK1_PLK1_ST	O60563	CCNT1	P53350	PLK1	T282	K277N	277	Missense	distal	-5	no	11.337	11.139	EPSD	TCGA;ICGC;COSMIC	10.919	Down-regulation
Other_PLK_PLK1_PLK1_ST	O60563	CCNT1	P53350	PLK1	S363	A356P	356	Missense	distal	-7	no	11.051	11.194	EPSD	TCGA;ICGC;COSMIC	10.919	Up-regulation
Other_PLK_PLK1_PLK1_ST	O60563	CCNT1	P53350	PLK1	S363	S363Y	363	Missense	central	0	yes	11.051	0.000	EPSD	TCGA;ICGC;COSMIC	10.919	Loss
Other_PLK_PLK1_PLK1_ST	O60563	CCNT1	P53350	PLK1	S363	P365S	365	Missense	proximal	2	no	11.051	12.528	EPSD	TCGA;ICGC;COSMIC	10.919	Up-regulation
Other_PLK_PLK1_PLK1_ST	O60563	CCNT1	P53350	PLK1	S549	S548N	548	Missense	proximal	-1	no	11.229	11.089	EPSD	TCGA;ICGC;COSMIC	10.919	Down-regulation
Other_PLK_PLK1_PLK1_ST	O60563	CCNT1	P53350	PLK1	S560	S564C	564	Missense	distal	4	no	12.630	12.103	EPSD	TCGA;ICGC;COSMIC	10.919	Down-regulation
Other_PLK_PLK1_PLK1_ST	O60563	CCNT1	P53350	PLK1	S560	S567C	567	Missense	distal	7	no	12.630	12.698	EPSD	TCGA;ICGC;COSMIC	10.919	Up-regulation
Other_PLK_PLK1_PLK1_ST	O60563	CCNT1	P53350	PLK1	S560	K557T	557	Missense	distal	-3	no	12.630	12.635	EPSD	TCGA;ICGC	10.919	Up-regulation
Other_PLK_PLK1_PLK1_ST	O60563	CCNT1	P53350	PLK1	S560	S560I	560	Missense	central	0	yes	12.630	0.000	EPSD	TCGA;ICGC;COSMIC	10.919	Loss
Other_PLK_PLK1_PLK1_ST	O60563	CCNT1	P53350	PLK1	S564	S564C	564	Missense	central	0	yes	13.753	0.000	PhosphoSitePlus	TCGA;ICGC;COSMIC	10.919	Loss
Other_PLK_PLK1_PLK1_ST	O60563	CCNT1	P53350	PLK1	S564	S567C	567	Missense	distal	3	no	13.753	13.689	PhosphoSitePlus	TCGA;ICGC;COSMIC	10.919	Down-regulation
Other_PLK_PLK1_PLK1_ST	O60563	CCNT1	P53350	PLK1	S564	K557T	557	Missense	distal	-7	no	13.753	14.109	PhosphoSitePlus	TCGA;ICGC	10.919	Up-regulation
Other_PLK_PLK1_PLK1_ST	O60563	CCNT1	P53350	PLK1	S564	S560I	560	Missense	distal	-4	no	13.753	13.787	PhosphoSitePlus	TCGA;ICGC;COSMIC	10.919	Up-regulation
Other_PLK_PLK1_PLK1_ST	O60563	CCNT1	P53350	PLK1	S577	R572C	572	Missense	distal	-5	no	11.112	10.446	EPSD	TCGA;ICGC;COSMIC	10.919	Loss
Other_PLK_PLK1_PLK1_ST	O60563	CCNT1	P53350	PLK1	S577	G582V	582	Missense	distal	5	no	11.112	10.757	EPSD	TCGA;ICGC;COSMIC	10.919	Loss
Other_PLK_PLK1_PLK1_ST	O60563	CCNT1	P53350	PLK1	T580	D586H	586	Missense	distal	6	no	11.250	10.456	EPSD	TCGA;ICGC;COSMIC	10.919	Loss
Other_PLK_PLK1_PLK1_ST	O60563	CCNT1	P53350	PLK1	T580	G582V	582	Missense	proximal	2	no	11.250	13.034	EPSD	TCGA;ICGC;COSMIC	10.919	Up-regulation
Other_PLK_PLK1_PLK1_ST	O60563	CCNT1	P53350	PLK1	T580	F585C	585	Missense	distal	5	no	11.250	11.285	EPSD	TCGA	10.919	Up-regulation
Other_PLK_PLK1_PLK1_ST	Q9Y2I6	NINL	P53350	PLK1	S87	S89F	89	Missense	proximal	2	no	14.014	13.463	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	10.919	Down-regulation
Other_PLK_PLK1_PLK1_ST	Q9Y2I6	NINL	P53350	PLK1	S87	A93S	93	Missense	distal	6	no	14.014	13.731	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	10.919	Down-regulation
Other_PLK_PLK1_PLK1_ST	Q9Y2I6	NINL	P53350	PLK1	S88	S89F	89	Missense	proximal	1	no	12.809	15.857	PhosphoSitePlus;EPSD	TCGA;ICGC;COSMIC	10.919	Up-regulation
Other_PLK_PLK1_PLK1_ST	Q9Y2I6	NINL	P53350	PLK1	S88	A93S	93	Missense	distal	5	no	12.809	12.242	PhosphoSitePlus;EPSD	TCGA;ICGC;COSMIC	10.919	Down-regulation
Other_PLK_PLK1_PLK1_ST	Q9Y2I6	NINL	P53350	PLK1	S448	R451W	451	Missense	distal	3	no	11.419	11.191	EPSD	TCGA;ICGC;COSMIC;GDSC;CCLE	10.919	Down-regulation
Other_PLK_PLK1_PLK1_ST	Q9Y2I6	NINL	P53350	PLK1	S448	E453Q	453	Missense	distal	5	no	11.419	11.260	EPSD	TCGA	10.919	Down-regulation
Other_PLK_PLK1_PLK1_ST	Q9Y2I6	NINL	P53350	PLK1	S448	G442R	442	Missense	distal	-6	no	11.419	11.518	EPSD	TCGA;ICGC;COSMIC	10.919	Up-regulation
Other_PLK_PLK1_PLK1_ST	Q9Y2I6	NINL	P53350	PLK1	S448	R451L	451	Missense	distal	3	no	11.419	11.397	EPSD	TCGA;ICGC;COSMIC	10.919	Down-regulation
Other_PLK_PLK1_PLK1_ST	Q9Y2I6	NINL	P53350	PLK1	S448	R446M	446	Missense	proximal	-2	no	11.419	11.189	EPSD	TCGA;ICGC;COSMIC	10.919	Down-regulation
Other_PLK_PLK1_PLK1_ST	Q9Y2I6	NINL	P53350	PLK1	S606	G601S	601	Missense	distal	-5	no	12.804	12.405	EPSD	TCGA;ICGC;COSMIC	10.919	Down-regulation
Other_PLK_PLK1_PLK1_ST	Q9Y2I6	NINL	P53350	PLK1	S686	H683Q	683	Missense	distal	-3	no	12.596	12.593	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	10.919	Down-regulation
Other_PLK_PLK1_PLK1_ST	Q9Y2I6	NINL	P53350	PLK1	S686	E680D	680	Missense	distal	-6	no	12.596	12.393	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	10.919	Down-regulation
Other_PLK_PLK1_PLK1_ST	Q9Y2I6	NINL	P53350	PLK1	T758	R754H	754	Missense	distal	-4	no	10.692	10.994	EPSD	TCGA;ICGC;COSMIC	10.919	Gain
Other_PLK_PLK1_PLK1_ST	Q9Y2I6	NINL	P53350	PLK1	S1267	R1264L	1264	Missense	distal	-3	no	13.812	13.754	EPSD	TCGA;ICGC;COSMIC	10.919	Down-regulation
Other_PLK_PLK1_PLK1_ST	Q9Y2I6	NINL	P53350	PLK1	S1267	R1264H	1264	Missense	distal	-3	no	13.812	13.140	EPSD	TCGA;ICGC;COSMIC	10.919	Down-regulation
Other_PLK_PLK1_PLK1_ST	Q9Y2I6	NINL	P53350	PLK1	S1267	L1268F	1268	Missense	proximal	1	no	13.812	14.893	EPSD	TCGA;ICGC;COSMIC	10.919	Up-regulation
Other_PLK_PLK1_PLK1_ST	Q9Y2I6	NINL	P53350	PLK1	S1267	Q1269H	1269	Missense	proximal	2	no	13.812	14.190	EPSD	TCGA;ICGC;COSMIC	10.919	Up-regulation
Other_PLK_PLK1_PLK1_ST	P60484	PTEN	P53350	PLK1	S227	T232A	232	Missense	distal	5	no	10.313	11.485	EPSD	TCGA;ICGC;COSMIC;GDSC;CCLE	10.919	Gain
Other_PLK_PLK1_PLK1_ST	P60484	PTEN	P53350	PLK1	S338	R335P	335	Missense	distal	-3	no	10.952	9.703	EPSD	TCGA;ICGC;COSMIC	10.919	Loss
Other_PLK_PLK1_PLK1_ST	P60484	PTEN	P53350	PLK1	S338	F341V	341	Missense	distal	3	no	10.952	11.044	EPSD	TCGA;ICGC;COSMIC;GDSC;CCLE	10.919	Up-regulation
Other_PLK_PLK1_PLK1_ST	P60484	PTEN	P53350	PLK1	S338	K342N	342	Missense	distal	4	no	10.952	11.101	EPSD	TCGA;ICGC;COSMIC	10.919	Up-regulation
Other_PLK_PLK1_PLK1_ST	P60484	PTEN	P53350	PLK1	S338	F337I	337	Missense	proximal	-1	no	10.952	11.508	EPSD	TCGA;ICGC;COSMIC	10.919	Up-regulation
Other_PLK_PLK1_PLK1_ST	P60484	PTEN	P53350	PLK1	S338	F341C	341	Missense	distal	3	no	10.952	10.828	EPSD	TCGA;ICGC;COSMIC	10.919	Loss
Other_PLK_PLK1_PLK1_ST	P60484	PTEN	P53350	PLK1	S380	E373K	373	Missense	distal	-7	no	11.480	11.176	PhosphoSitePlus;EPSD	TCGA;ICGC	10.919	Down-regulation
Other_PLK_PLK1_PLK1_ST	P30305	CDC25B	P53350	PLK1	S50	S49A	49	Missense	proximal	-1	no	13.331	12.864	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	10.919	Down-regulation
Other_PLK_PLK1_PLK1_ST	P30305	CDC25B	P53350	PLK1	T167	S160I	160	Missense	distal	-7	no	12.471	12.009	EPSD;PhosphoSitePlus	TCGA	10.919	Down-regulation
Other_PLK_PLK1_PLK1_ST	P30305	CDC25B	P53350	PLK1	T167	S160C	160	Missense	distal	-7	no	12.471	11.854	EPSD;PhosphoSitePlus	TCGA;COSMIC	10.919	Down-regulation
Other_PLK_PLK1_PLK1_ST	P30305	CDC25B	P53350	PLK1	T167	V162M	162	Missense	distal	-5	no	12.471	12.324	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	10.919	Down-regulation
Other_PLK_PLK1_PLK1_ST	P30305	CDC25B	P53350	PLK1	T167	R164Q	164	Missense	distal	-3	no	12.471	11.797	EPSD;PhosphoSitePlus	TCGA	10.919	Down-regulation
Other_PLK_PLK1_PLK1_ST	P30305	CDC25B	P53350	PLK1	S291	S294T	294	Missense	distal	3	no	13.114	12.977	EPSD;PhosphoSitePlus	TCGA;COSMIC	10.919	Down-regulation
Other_PLK_PLK1_PLK1_ST	P30305	CDC25B	P53350	PLK1	S291	A284V	284	Missense	distal	-7	no	13.114	13.171	EPSD;PhosphoSitePlus	TCGA;COSMIC	10.919	Up-regulation
Other_PLK_PLK1_PLK1_ST	P30305	CDC25B	P53350	PLK1	S397	R390Q	390	Missense	distal	-7	no	13.968	14.369	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	10.919	Up-regulation
Other_PLK_PLK1_PLK1_ST	P30305	CDC25B	P53350	PLK1	S465	E464D	464	Missense	proximal	-1	no	12.264	13.061	EPSD;PhosphoSitePlus	TCGA;ICGC	10.919	Up-regulation
Other_PLK_PLK1_PLK1_ST	P30305	CDC25B	P53350	PLK1	S465	R461C	461	Missense	distal	-4	no	12.264	12.018	EPSD;PhosphoSitePlus	TCGA;COSMIC	10.919	Down-regulation
Other_PLK_PLK1_PLK1_ST	P30305	CDC25B	P53350	PLK1	S465	A463V	463	Missense	proximal	-2	no	12.264	12.224	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	10.919	Down-regulation
Other_PLK_PLK1_PLK1_ST	P30305	CDC25B	P53350	PLK1	S470	E464D	464	Missense	distal	-6	no	11.498	11.295	EPSD	TCGA;ICGC	10.919	Down-regulation
Other_PLK_PLK1_PLK1_ST	P30305	CDC25B	P53350	PLK1	S470	A463V	463	Missense	distal	-7	no	11.498	11.555	EPSD	TCGA;ICGC;COSMIC	10.919	Up-regulation
Other_PLK_PLK1_PLK1_ST	P30305	CDC25B	P53350	PLK1	S513	Y520H	520	Missense	distal	7	no	11.334	11.265	EPSD;PhosphoSitePlus	TCGA;COSMIC	10.919	Down-regulation
Other_PLK_PLK1_PLK1_ST	P30305	CDC25B	P53350	PLK1	S513	R506H	506	Missense	distal	-7	no	11.334	11.713	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	10.919	Up-regulation
Other_PLK_PLK1_PLK1_ST	P30305	CDC25B	P53350	PLK1	S563	R568W	568	Missense	distal	5	no	11.189	10.930	EPSD	TCGA;COSMIC	10.919	Down-regulation
Other_PLK_PLK1_PLK1_ST	P30305	CDC25B	P53350	PLK1	S563	R562H	562	Missense	proximal	-1	no	11.189	12.186	EPSD	TCGA;COSMIC;CCLE	10.919	Up-regulation
Other_PLK_PLK1_PLK1_ST	P33981	TTK	P53350	PLK1	S7	T12R	12	Missense	distal	5	no	10.328	11.278	EPSD	TCGA;ICGC;COSMIC	10.919	Gain
Other_PLK_PLK1_PLK1_ST	P33981	TTK	P53350	PLK1	S37	L32V	32	Missense	distal	-5	no	12.888	12.436	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	10.919	Down-regulation
Other_PLK_PLK1_PLK1_ST	P33981	TTK	P53350	PLK1	S49	V52A	52	Missense	distal	3	no	11.653	11.325	EPSD	TCGA;ICGC;COSMIC	10.919	Down-regulation
Other_PLK_PLK1_PLK1_ST	P33981	TTK	P53350	PLK1	S291	M297I	297	Missense	distal	6	no	14.312	14.568	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	10.919	Up-regulation
Other_PLK_PLK1_PLK1_ST	P33981	TTK	P53350	PLK1	S291	S291L	291	Missense	central	0	yes	14.312	0.000	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	10.919	Loss
Other_PLK_PLK1_PLK1_ST	P33981	TTK	P53350	PLK1	S291	T288I	288	Missense	distal	-3	no	14.312	14.334	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	10.919	Up-regulation
Other_PLK_PLK1_PLK1_ST	P33981	TTK	P53350	PLK1	S353	T360K	360	Missense	distal	7	no	11.291	11.356	EPSD	TCGA;ICGC;COSMIC	10.919	Up-regulation
Other_PLK_PLK1_PLK1_ST	P33981	TTK	P53350	PLK1	S363	T360K	360	Missense	distal	-3	no	14.324	14.319	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	10.919	Down-regulation
Other_PLK_PLK1_PLK1_ST	P33981	TTK	P53350	PLK1	T594	E592D	592	Missense	proximal	-2	no	10.561	10.955	EPSD;PhosphoSitePlus	TCGA;COSMIC	10.919	Gain
Other_PLK_PLK1_PLK1_ST	P33981	TTK	P53350	PLK1	S742	D749V	749	Missense	distal	7	no	12.461	12.536	EPSD	TCGA;COSMIC	10.919	Up-regulation
Other_PLK_PLK1_PLK1_ST	P33981	TTK	P53350	PLK1	S742	S742Y	742	Missense	central	0	yes	12.461	0.000	EPSD	TCGA	10.919	Loss
Other_PLK_PLK1_PLK1_ST	P33981	TTK	P53350	PLK1	S742	I741M	741	Missense	proximal	-1	no	12.461	12.516	EPSD	TCGA;COSMIC	10.919	Up-regulation
Other_PLK_PLK1_PLK1_ST	P33981	TTK	P53350	PLK1	S742	K743T	743	Missense	proximal	1	no	12.461	12.813	EPSD	TCGA;COSMIC	10.919	Up-regulation
Other_PLK_PLK1_PLK1_ST	P33981	TTK	P53350	PLK1	T831	S824F	824	Missense	distal	-7	no	12.235	11.777	EPSD	TCGA;COSMIC	10.919	Down-regulation
Other_PLK_PLK1_PLK1_ST	P33981	TTK	P53350	PLK1	S845	G839S	839	Missense	distal	-6	no	13.316	13.862	EPSD	TCGA;COSMIC	10.919	Up-regulation
Other_PLK_PLK1_PLK1_ST	Q96BK5	PINX1	P53350	PLK1	S161	P156L	156	Missense	distal	-5	no	14.209	14.610	EPSD	TCGA;ICGC;COSMIC	10.919	Up-regulation
Other_PLK_PLK1_PLK1_ST	Q96BK5	PINX1	P53350	PLK1	T177	E180K	180	Missense	distal	3	no	11.825	11.619	EPSD	TCGA;COSMIC	10.919	Down-regulation
Other_PLK_PLK1_PLK1_ST	Q96BK5	PINX1	P53350	PLK1	S226	A219V	219	Missense	distal	-7	no	11.711	11.768	PhosphoSitePlus;EPSD	TCGA;ICGC	10.919	Up-regulation
Other_PLK_PLK1_PLK1_ST	Q96BK5	PINX1	P53350	PLK1	T317	A312T	312	Missense	distal	-5	no	13.138	13.069	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC;CCLE	10.919	Down-regulation
Other_PLK_PLK1_PLK1_ST	Q96BK5	PINX1	P53350	PLK1	T317	T317M	317	Missense	central	0	yes	13.138	0.000	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	10.919	Loss
Other_PLK_PLK1_PLK1_ST	Q96BK5	PINX1	P53350	PLK1	T317	K321N	321	Missense	distal	4	no	13.138	13.287	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	10.919	Up-regulation
Other_PLK_PLK1_PLK1_ST	Q96BK5	PINX1	P53350	PLK1	T317	E316K	316	Missense	proximal	-1	no	13.138	12.567	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	10.919	Down-regulation
Other_PLK_PLK1_PLK1_ST	Q9H1A4	ANAPC1	P53350	PLK1	S212	E219K	219	Missense	distal	7	no	11.649	11.722	EPSD	TCGA;ICGC;COSMIC	10.919	Up-regulation
Other_PLK_PLK1_PLK1_ST	Q9H1A4	ANAPC1	P53350	PLK1	S212	F211V	211	Missense	proximal	-1	no	11.649	11.231	EPSD	TCGA;ICGC;COSMIC	10.919	Down-regulation
Other_PLK_PLK1_PLK1_ST	Q9H1A4	ANAPC1	P53350	PLK1	S313	P314S	314	Missense	proximal	1	no	11.152	10.030	EPSD	TCGA;ICGC;COSMIC	10.919	Loss
Other_PLK_PLK1_PLK1_ST	Q9H1A4	ANAPC1	P53350	PLK1	S313	S313P	313	Missense	central	0	yes	11.152	0.000	EPSD	TCGA;ICGC;COSMIC	10.919	Loss
Other_PLK_PLK1_PLK1_ST	Q9H1A4	ANAPC1	P53350	PLK1	S313	P314L	314	Missense	proximal	1	no	11.152	11.998	EPSD	TCGA;ICGC;COSMIC	10.919	Up-regulation
Other_PLK_PLK1_PLK1_ST	Q9H1A4	ANAPC1	P53350	PLK1	S323	R330C	330	Missense	distal	7	no	12.107	12.159	EPSD	TCGA;ICGC;COSMIC	10.919	Up-regulation
Other_PLK_PLK1_PLK1_ST	Q9H1A4	ANAPC1	P53350	PLK1	S323	R330H	330	Missense	distal	7	no	12.107	12.077	EPSD	TCGA;CCLE	10.919	Down-regulation
Other_PLK_PLK1_PLK1_ST	Q9H1A4	ANAPC1	P53350	PLK1	S355	S355F	355	Missense	central	0	yes	12.258	0.000	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	10.919	Loss
Other_PLK_PLK1_PLK1_ST	Q9H1A4	ANAPC1	P53350	PLK1	S355	S362F	362	Missense	distal	7	no	12.258	12.328	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	10.919	Up-regulation
Other_PLK_PLK1_PLK1_ST	Q9H1A4	ANAPC1	P53350	PLK1	S377	R380I	380	Missense	distal	3	no	13.023	13.176	EPSD;PhosphoSitePlus	TCGA;ICGC	10.919	Up-regulation
Other_PLK_PLK1_PLK1_ST	Q9H1A4	ANAPC1	P53350	PLK1	S377	N370S	370	Missense	distal	-7	no	13.023	13.233	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	10.919	Up-regulation
Other_PLK_PLK1_PLK1_ST	Q9H1A4	ANAPC1	P53350	PLK1	S386	R380I	380	Missense	distal	-6	no	11.140	11.657	EPSD	TCGA;ICGC	10.919	Up-regulation
Other_PLK_PLK1_PLK1_ST	Q9H1A4	ANAPC1	P53350	PLK1	S386	N392D	392	Missense	distal	6	no	11.140	11.360	EPSD	TCGA;ICGC;COSMIC	10.919	Up-regulation
Other_PLK_PLK1_PLK1_ST	Q9H1A4	ANAPC1	P53350	PLK1	S386	P387L	387	Missense	proximal	1	no	11.140	11.986	EPSD	TCGA;ICGC;COSMIC	10.919	Up-regulation
Other_PLK_PLK1_PLK1_ST	Q9H1A4	ANAPC1	P53350	PLK1	S386	S386Y	386	Missense	central	0	yes	11.140	0.000	EPSD	TCGA;ICGC;COSMIC	10.919	Loss
Other_PLK_PLK1_PLK1_ST	Q9H1A4	ANAPC1	P53350	PLK1	S386	S391A	391	Missense	distal	5	no	11.140	11.707	EPSD	TCGA;ICGC;COSMIC	10.919	Up-regulation
Other_PLK_PLK1_PLK1_ST	Q9H1A4	ANAPC1	P53350	PLK1	T524	R527W	527	Missense	distal	3	no	11.557	11.329	EPSD	TCGA;ICGC;COSMIC	10.919	Down-regulation
Other_PLK_PLK1_PLK1_ST	Q9H1A4	ANAPC1	P53350	PLK1	T524	M525V	525	Missense	proximal	1	no	11.557	10.401	EPSD	TCGA;ICGC;COSMIC	10.919	Loss
Other_PLK_PLK1_PLK1_ST	Q9H1A4	ANAPC1	P53350	PLK1	T530	R527W	527	Missense	distal	-3	no	12.042	11.260	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	10.919	Down-regulation
Other_PLK_PLK1_PLK1_ST	Q9H1A4	ANAPC1	P53350	PLK1	T530	D533H	533	Missense	distal	3	no	12.042	11.804	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	10.919	Down-regulation
Other_PLK_PLK1_PLK1_ST	Q9H1A4	ANAPC1	P53350	PLK1	T530	M525V	525	Missense	distal	-5	no	12.042	12.189	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	10.919	Up-regulation
Other_PLK_PLK1_PLK1_ST	Q9H1A4	ANAPC1	P53350	PLK1	S547	L545F	545	Missense	proximal	-2	no	10.928	10.318	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	10.919	Loss
Other_PLK_PLK1_PLK1_ST	Q9H1A4	ANAPC1	P53350	PLK1	S563	P558L	558	Missense	distal	-5	no	10.597	10.999	EPSD	TCGA;ICGC;COSMIC	10.919	Gain
Other_PLK_PLK1_PLK1_ST	Q9H1A4	ANAPC1	P53350	PLK1	S564	D568G	568	Missense	distal	4	no	12.442	12.353	EPSD	TCGA;ICGC;COSMIC	10.919	Down-regulation
Other_PLK_PLK1_PLK1_ST	Q9H1A4	ANAPC1	P53350	PLK1	S564	D568N	568	Missense	distal	4	no	12.442	12.203	EPSD	TCGA;ICGC;COSMIC	10.919	Down-regulation
Other_PLK_PLK1_PLK1_ST	Q9H1A4	ANAPC1	P53350	PLK1	S564	L570F	570	Missense	distal	6	no	12.442	11.826	EPSD	TCGA;ICGC;COSMIC	10.919	Down-regulation
Other_PLK_PLK1_PLK1_ST	Q9H1A4	ANAPC1	P53350	PLK1	S564	P558L	558	Missense	distal	-6	no	12.442	12.731	EPSD	TCGA;ICGC;COSMIC	10.919	Up-regulation
Other_PLK_PLK1_PLK1_ST	Q9H1A4	ANAPC1	P53350	PLK1	S569	L570F	570	Missense	proximal	1	no	10.344	11.425	EPSD	TCGA;ICGC;COSMIC	10.919	Gain
Other_PLK_PLK1_PLK1_ST	Q9H1A4	ANAPC1	P53350	PLK1	S686	E684Q	684	Missense	proximal	-2	no	12.056	9.397	EPSD	TCGA;ICGC;COSMIC	10.919	Loss
Other_PLK_PLK1_PLK1_ST	Q9H1A4	ANAPC1	P53350	PLK1	S686	L687I	687	Missense	proximal	1	no	12.056	11.848	EPSD	TCGA;ICGC	10.919	Down-regulation
Other_PLK_PLK1_PLK1_ST	Q9H1A4	ANAPC1	P53350	PLK1	S686	R679G	679	Missense	distal	-7	no	12.056	11.857	EPSD	TCGA;ICGC;COSMIC	10.919	Down-regulation
Other_PLK_PLK1_PLK1_ST	Q9H1A4	ANAPC1	P53350	PLK1	S686	P693S	693	Missense	distal	7	no	12.056	12.029	EPSD	TCGA;ICGC;COSMIC	10.919	Down-regulation
Other_PLK_PLK1_PLK1_ST	Q9H1A4	ANAPC1	P53350	PLK1	S688	E684Q	684	Missense	distal	-4	no	13.345	13.077	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	10.919	Down-regulation
Other_PLK_PLK1_PLK1_ST	Q9H1A4	ANAPC1	P53350	PLK1	S688	L687I	687	Missense	proximal	-1	no	13.345	13.822	EPSD;PhosphoSitePlus	TCGA;ICGC	10.919	Up-regulation
Other_PLK_PLK1_PLK1_ST	Q9H1A4	ANAPC1	P53350	PLK1	S688	P693S	693	Missense	distal	5	no	13.345	12.958	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	10.919	Down-regulation
Other_PLK_PLK1_PLK1_ST	Q9H1A4	ANAPC1	P53350	PLK1	S727	R726I	726	Missense	proximal	-1	no	10.630	11.584	EPSD	TCGA;ICGC	10.919	Gain
Other_PLK_PLK1_PLK1_ST	Q9H1A4	ANAPC1	P53350	PLK1	S886	E891A	891	Missense	distal	5	no	13.913	14.771	EPSD	TCGA;ICGC;COSMIC	10.919	Up-regulation
Other_PLK_PLK1_PLK1_ST	Q9H1A4	ANAPC1	P53350	PLK1	S892	E891A	891	Missense	proximal	-1	no	12.506	12.043	EPSD	TCGA;ICGC;COSMIC	10.919	Down-regulation
Other_PLK_PLK1_PLK1_ST	Q9H1A4	ANAPC1	P53350	PLK1	S892	R898K	898	Missense	distal	6	no	12.506	12.866	EPSD	TCGA;ICGC	10.919	Up-regulation
Other_PLK_PLK1_PLK1_ST	Q9H1A4	ANAPC1	P53350	PLK1	S893	E891A	891	Missense	proximal	-2	no	11.126	8.948	EPSD	TCGA;ICGC;COSMIC	10.919	Loss
Other_PLK_PLK1_PLK1_ST	Q9H1A4	ANAPC1	P53350	PLK1	S893	R898K	898	Missense	distal	5	no	11.126	10.501	EPSD	TCGA;ICGC	10.919	Loss
Other_PLK_PLK1_PLK1_ST	Q9H1A4	ANAPC1	P53350	PLK1	S1058	E1061K	1061	Missense	distal	3	no	11.200	10.994	EPSD	TCGA;ICGC	10.919	Down-regulation
Other_PLK_PLK1_PLK1_ST	Q99661	KIF2C	P53350	PLK1	S519	E512Q	512	Missense	distal	-7	no	12.443	12.407	EPSD	TCGA;COSMIC	10.919	Down-regulation
Other_PLK_PLK1_PLK1_ST	Q99661	KIF2C	P53350	PLK1	S551	G554A	554	Missense	distal	3	no	14.177	13.998	EPSD	TCGA;COSMIC	10.919	Down-regulation
Other_PLK_PLK1_PLK1_ST	Q99661	KIF2C	P53350	PLK1	S551	I553M	553	Missense	proximal	2	no	14.177	13.753	EPSD	TCGA;COSMIC	10.919	Down-regulation
Other_PLK_PLK1_PLK1_ST	Q99661	KIF2C	P53350	PLK1	S589	D583N	583	Missense	distal	-6	no	14.763	14.650	EPSD	TCGA;COSMIC	10.919	Down-regulation
Other_PLK_PLK1_PLK1_ST	Q99661	KIF2C	P53350	PLK1	S621	L620F	620	Missense	proximal	-1	no	11.674	11.595	EPSD;PhosphoSitePlus	TCGA;COSMIC	10.919	Down-regulation
Other_PLK_PLK1_PLK1_ST	Q99661	KIF2C	P53350	PLK1	S621	E624Q	624	Missense	distal	3	no	11.674	11.566	EPSD;PhosphoSitePlus	TCGA	10.919	Down-regulation
Other_PLK_PLK1_PLK1_ST	Q99661	KIF2C	P53350	PLK1	S621	A614V	614	Missense	distal	-7	no	11.674	11.731	EPSD;PhosphoSitePlus	TCGA;COSMIC;CCLE	10.919	Up-regulation
Other_PLK_PLK1_PLK1_ST	Q99661	KIF2C	P53350	PLK1	S621	E623K	623	Missense	proximal	2	no	11.674	11.505	EPSD;PhosphoSitePlus	TCGA;COSMIC	10.919	Down-regulation
Other_PLK_PLK1_PLK1_ST	Q99661	KIF2C	P53350	PLK1	S621	S628F	628	Missense	distal	7	no	11.674	11.744	EPSD;PhosphoSitePlus	TCGA;COSMIC	10.919	Up-regulation
Other_PLK_PLK1_PLK1_ST	Q99661	KIF2C	P53350	PLK1	S621	E625G	625	Missense	distal	4	no	11.674	11.600	EPSD;PhosphoSitePlus	TCGA;COSMIC	10.919	Down-regulation
Other_PLK_PLK1_PLK1_ST	Q99661	KIF2C	P53350	PLK1	S621	E625K	625	Missense	distal	4	no	11.674	11.301	EPSD;PhosphoSitePlus	TCGA	10.919	Down-regulation
Other_PLK_PLK1_PLK1_ST	Q99661	KIF2C	P53350	PLK1	S628	E625G	625	Missense	distal	-3	no	9.993	10.935	EPSD	TCGA;COSMIC	10.919	Gain
Other_PLK_PLK1_PLK1_ST	Q99661	KIF2C	P53350	PLK1	S633	S628F	628	Missense	distal	-5	no	13.762	13.501	PhosphoSitePlus;EPSD	TCGA;COSMIC	10.919	Down-regulation
Other_PLK_PLK1_PLK1_ST	P35568	IRS1	P53350	PLK1	S99	I95M	95	Missense	distal	-4	no	11.482	11.172	EPSD	TCGA;ICGC;COSMIC	10.919	Down-regulation
Other_PLK_PLK1_PLK1_ST	P35568	IRS1	P53350	PLK1	S99	H92Q	92	Missense	distal	-7	no	11.482	11.502	EPSD	TCGA;ICGC	10.919	Up-regulation
Other_PLK_PLK1_PLK1_ST	P35568	IRS1	P53350	PLK1	S193	V195M	195	Missense	proximal	2	no	11.581	11.374	EPSD	TCGA;ICGC;COSMIC	10.919	Down-regulation
Other_PLK_PLK1_PLK1_ST	P35568	IRS1	P53350	PLK1	S277	C276F	276	Missense	proximal	-1	no	9.774	11.096	EPSD	TCGA;ICGC;COSMIC	10.919	Gain
Other_PLK_PLK1_PLK1_ST	P35568	IRS1	P53350	PLK1	S330	D331V	331	Missense	proximal	1	no	10.743	11.376	EPSD	TCGA;ICGC;COSMIC	10.919	Gain
Other_PLK_PLK1_PLK1_ST	P35568	IRS1	P53350	PLK1	S330	T335I	335	Missense	distal	5	no	10.743	11.645	EPSD	TCGA;ICGC;COSMIC	10.919	Gain
Other_PLK_PLK1_PLK1_ST	P35568	IRS1	P53350	PLK1	T335	D331V	331	Missense	distal	-4	no	10.868	10.961	EPSD	TCGA;ICGC;COSMIC	10.919	Gain
Other_PLK_PLK1_PLK1_ST	P35568	IRS1	P53350	PLK1	T335	R338H	338	Missense	distal	3	no	10.868	10.999	EPSD	TCGA;ICGC;COSMIC	10.919	Gain
Other_PLK_PLK1_PLK1_ST	P35568	IRS1	P53350	PLK1	T335	R338C	338	Missense	distal	3	no	10.868	10.927	EPSD	TCGA;ICGC;COSMIC	10.919	Gain
Other_PLK_PLK1_PLK1_ST	P35568	IRS1	P53350	PLK1	T335	A328T	328	Missense	distal	-7	no	10.868	11.213	EPSD	TCGA;ICGC;COSMIC	10.919	Gain
Other_PLK_PLK1_PLK1_ST	P35568	IRS1	P53350	PLK1	S345	R338H	338	Missense	distal	-7	no	12.466	12.846	EPSD	TCGA;ICGC;COSMIC	10.919	Up-regulation
Other_PLK_PLK1_PLK1_ST	P35568	IRS1	P53350	PLK1	S345	R338C	338	Missense	distal	-7	no	12.466	12.346	EPSD	TCGA;ICGC;COSMIC	10.919	Down-regulation
Other_PLK_PLK1_PLK1_ST	P35568	IRS1	P53350	PLK1	S345	P346H	346	Missense	proximal	1	no	12.466	11.577	EPSD	TCGA;ICGC	10.919	Down-regulation
Other_PLK_PLK1_PLK1_ST	P35568	IRS1	P53350	PLK1	S372	R373C	373	Missense	proximal	1	no	14.136	15.535	EPSD	TCGA;ICGC;COSMIC	10.919	Up-regulation
Other_PLK_PLK1_PLK1_ST	P35568	IRS1	P53350	PLK1	S372	P378S	378	Missense	distal	6	no	14.136	13.991	EPSD	TCGA;ICGC;COSMIC	10.919	Down-regulation
Other_PLK_PLK1_PLK1_ST	P35568	IRS1	P53350	PLK1	S398	S395C	395	Missense	distal	-3	no	11.301	11.337	EPSD	TCGA;ICGC;COSMIC	10.919	Up-regulation
Other_PLK_PLK1_PLK1_ST	P35568	IRS1	P53350	PLK1	S415	R411Q	411	Missense	distal	-4	no	11.677	11.965	EPSD	TCGA;ICGC	10.919	Up-regulation
Other_PLK_PLK1_PLK1_ST	P35568	IRS1	P53350	PLK1	S427	S428L	428	Missense	proximal	1	no	9.415	11.382	EPSD	TCGA;ICGC;COSMIC	10.919	Gain
Other_PLK_PLK1_PLK1_ST	P35568	IRS1	P53350	PLK1	S449	V445I	445	Missense	distal	-4	no	11.095	11.229	EPSD	TCGA;ICGC;COSMIC	10.919	Up-regulation
Other_PLK_PLK1_PLK1_ST	P35568	IRS1	P53350	PLK1	S449	R443H	443	Missense	distal	-6	no	11.095	11.554	EPSD	TCGA;ICGC	10.919	Up-regulation
Other_PLK_PLK1_PLK1_ST	P35568	IRS1	P53350	PLK1	T552	P556S	556	Missense	distal	4	no	11.154	11.476	EPSD	TCGA;ICGC;COSMIC	10.919	Up-regulation
Other_PLK_PLK1_PLK1_ST	P35568	IRS1	P53350	PLK1	T552	E553D	553	Missense	proximal	1	no	11.154	11.398	EPSD	TCGA;ICGC;COSMIC	10.919	Up-regulation
Other_PLK_PLK1_PLK1_ST	P35568	IRS1	P53350	PLK1	T605	H607R	607	Missense	proximal	2	no	11.317	10.615	EPSD	TCGA;ICGC	10.919	Loss
Other_PLK_PLK1_PLK1_ST	P35568	IRS1	P53350	PLK1	T605	G611C	611	Missense	distal	6	no	11.317	10.589	EPSD	TCGA;ICGC;COSMIC	10.919	Loss
Other_PLK_PLK1_PLK1_ST	P35568	IRS1	P53350	PLK1	T605	R600C	600	Missense	distal	-5	no	11.317	10.652	EPSD	TCGA;ICGC;COSMIC	10.919	Loss
Other_PLK_PLK1_PLK1_ST	P35568	IRS1	P53350	PLK1	S741	N742D	742	Missense	proximal	1	no	11.207	11.401	EPSD	TCGA;ICGC;COSMIC	10.919	Up-regulation
Other_PLK_PLK1_PLK1_ST	P35568	IRS1	P53350	PLK1	T1045	P1047S	1047	Missense	proximal	2	no	10.889	12.365	EPSD	TCGA;ICGC;COSMIC	10.919	Gain
Other_PLK_PLK1_PLK1_ST	P35568	IRS1	P53350	PLK1	S1078	R1081H	1081	Missense	distal	3	no	11.775	11.906	EPSD	TCGA;ICGC;COSMIC	10.919	Up-regulation
Other_PLK_PLK1_PLK1_ST	P35568	IRS1	P53350	PLK1	S1132	S1133N	1133	Missense	proximal	1	no	11.149	11.889	EPSD	TCGA;ICGC	10.919	Up-regulation
Other_PLK_PLK1_PLK1_ST	P35568	IRS1	P53350	PLK1	S1227	S1223G	1223	Missense	distal	-4	no	11.646	10.992	EPSD	TCGA;ICGC;COSMIC	10.919	Down-regulation
Other_PLK_PLK1_PLK1_ST	P35568	IRS1	P53350	PLK1	S1227	S1233G	1233	Missense	distal	6	no	11.646	11.442	EPSD	TCGA;ICGC;COSMIC	10.919	Down-regulation
Other_PLK_PLK1_PLK1_ST	P35568	IRS1	P53350	PLK1	S1231	S1233G	1233	Missense	proximal	2	no	14.335	12.755	EPSD	TCGA;ICGC;COSMIC	10.919	Down-regulation
Other_PLK_PLK1_PLK1_ST	Q49MG5	MAP9	P53350	PLK1	S41	R35H	35	Missense	distal	-6	no	10.736	11.195	EPSD	TCGA;ICGC;COSMIC	10.919	Gain
Other_PLK_PLK1_PLK1_ST	Q49MG5	MAP9	P53350	PLK1	S154	L153I	153	Missense	proximal	-1	no	10.858	11.335	EPSD	TCGA;ICGC;COSMIC	10.919	Gain
Other_PLK_PLK1_PLK1_ST	Q49MG5	MAP9	P53350	PLK1	S165	S165I	165	Missense	central	0	yes	11.318	0.000	EPSD	TCGA;ICGC;COSMIC	10.919	Loss
Other_PLK_PLK1_PLK1_ST	Q49MG5	MAP9	P53350	PLK1	S212	S213F	213	Missense	proximal	1	no	9.076	12.124	EPSD	TCGA;ICGC;COSMIC	10.919	Gain
Other_PLK_PLK1_PLK1_ST	Q49MG5	MAP9	P53350	PLK1	S238	L233V	233	Missense	distal	-5	no	12.706	12.253	EPSD	TCGA;ICGC;COSMIC	10.919	Down-regulation
Other_PLK_PLK1_PLK1_ST	Q49MG5	MAP9	P53350	PLK1	S238	P235L	235	Missense	distal	-3	no	12.706	13.898	EPSD	TCGA;ICGC;COSMIC	10.919	Up-regulation
Other_PLK_PLK1_PLK1_ST	Q49MG5	MAP9	P53350	PLK1	S238	E236D	236	Missense	proximal	-2	no	12.706	13.099	EPSD	TCGA;ICGC;COSMIC	10.919	Up-regulation
Other_PLK_PLK1_PLK1_ST	Q49MG5	MAP9	P53350	PLK1	S238	C239F	239	Missense	proximal	1	no	12.706	15.519	EPSD	TCGA;ICGC;COSMIC	10.919	Up-regulation
Other_PLK_PLK1_PLK1_ST	Q49MG5	MAP9	P53350	PLK1	S238	S238L	238	Missense	central	0	yes	12.706	0.000	EPSD	TCGA;ICGC;COSMIC	10.919	Loss
Other_PLK_PLK1_PLK1_ST	Q49MG5	MAP9	P53350	PLK1	S242	P235L	235	Missense	distal	-7	no	10.949	10.855	EPSD	TCGA;ICGC;COSMIC	10.919	Loss
Other_PLK_PLK1_PLK1_ST	Q49MG5	MAP9	P53350	PLK1	S242	E236D	236	Missense	distal	-6	no	10.949	10.746	EPSD	TCGA;ICGC;COSMIC	10.919	Loss
Other_PLK_PLK1_PLK1_ST	Q49MG5	MAP9	P53350	PLK1	S242	C239F	239	Missense	distal	-3	no	10.949	10.284	EPSD	TCGA;ICGC;COSMIC	10.919	Loss
Other_PLK_PLK1_PLK1_ST	Q49MG5	MAP9	P53350	PLK1	S242	S238L	238	Missense	distal	-4	no	10.949	10.756	EPSD	TCGA;ICGC;COSMIC	10.919	Loss
Other_PLK_PLK1_PLK1_ST	Q49MG5	MAP9	P53350	PLK1	S255	Q250L	250	Missense	distal	-5	no	11.924	12.644	EPSD	TCGA;ICGC;COSMIC	10.919	Up-regulation
Other_PLK_PLK1_PLK1_ST	Q49MG5	MAP9	P53350	PLK1	S255	S260F	260	Missense	distal	5	no	11.924	12.018	EPSD	TCGA;ICGC;COSMIC	10.919	Up-regulation
Other_PLK_PLK1_PLK1_ST	Q49MG5	MAP9	P53350	PLK1	S289	S289L	289	Missense	central	0	yes	13.258	0.000	PhosphoSitePlus	TCGA;ICGC;COSMIC	10.919	Loss
Other_PLK_PLK1_PLK1_ST	Q49MG5	MAP9	P53350	PLK1	S289	E287D	287	Missense	proximal	-2	no	13.258	13.652	PhosphoSitePlus	TCGA;ICGC;COSMIC	10.919	Up-regulation
Other_PLK_PLK1_PLK1_ST	Q49MG5	MAP9	P53350	PLK1	S305	E300V	300	Missense	distal	-5	no	10.677	10.986	EPSD	TCGA;ICGC;COSMIC	10.919	Gain
Other_PLK_PLK1_PLK1_ST	Q49MG5	MAP9	P53350	PLK1	S336	P331L	331	Missense	distal	-5	no	11.933	12.334	EPSD	TCGA;ICGC;COSMIC	10.919	Up-regulation
Other_PLK_PLK1_PLK1_ST	Q49MG5	MAP9	P53350	PLK1	S336	Q337H	337	Missense	proximal	1	no	11.933	11.351	EPSD	TCGA;ICGC	10.919	Down-regulation
Other_PLK_PLK1_PLK1_ST	Q49MG5	MAP9	P53350	PLK1	T364	A371T	371	Missense	distal	7	no	11.677	11.637	EPSD	TCGA;ICGC;COSMIC	10.919	Down-regulation
Other_PLK_PLK1_PLK1_ST	Q49MG5	MAP9	P53350	PLK1	T364	N366D	366	Missense	proximal	2	no	11.677	11.462	EPSD	TCGA;ICGC;COSMIC	10.919	Down-regulation
Other_PLK_PLK1_PLK1_ST	Q49MG5	MAP9	P53350	PLK1	T364	S369F	369	Missense	distal	5	no	11.677	11.771	EPSD	TCGA;ICGC;COSMIC	10.919	Up-regulation
Other_PLK_PLK1_PLK1_ST	Q49MG5	MAP9	P53350	PLK1	T364	K359N	359	Missense	distal	-5	no	11.677	11.479	EPSD	TCGA;ICGC;COSMIC	10.919	Down-regulation
Other_PLK_PLK1_PLK1_ST	Q49MG5	MAP9	P53350	PLK1	T364	N365H	365	Missense	proximal	1	no	11.677	11.170	EPSD	TCGA	10.919	Down-regulation
Other_PLK_PLK1_PLK1_ST	Q49MG5	MAP9	P53350	PLK1	T364	N357H	357	Missense	distal	-7	no	11.677	11.770	EPSD	TCGA;ICGC	10.919	Up-regulation
Other_PLK_PLK1_PLK1_ST	Q49MG5	MAP9	P53350	PLK1	S370	A371T	371	Missense	proximal	1	no	10.462	10.924	EPSD	TCGA;ICGC;COSMIC	10.919	Gain
Other_PLK_PLK1_PLK1_ST	Q49MG5	MAP9	P53350	PLK1	S370	R374S	374	Missense	distal	4	no	10.462	11.407	EPSD	TCGA;ICGC;COSMIC	10.919	Gain
Other_PLK_PLK1_PLK1_ST	Q49MG5	MAP9	P53350	PLK1	S625	E630K	630	Missense	distal	5	no	12.527	12.538	EPSD	TCGA;ICGC;COSMIC	10.919	Up-regulation
Other_PLK_PLK1_PLK1_ST	O95613	PCNT	P53350	PLK1	S61	A62T	62	Missense	proximal	1	no	10.676	11.139	EPSD	TCGA;ICGC;COSMIC;GDSC;CCLE	10.919	Gain
Other_PLK_PLK1_PLK1_ST	O95613	PCNT	P53350	PLK1	T78	D80Y	80	Missense	proximal	2	no	12.201	11.834	EPSD	TCGA;ICGC;COSMIC	10.919	Down-regulation
Other_PLK_PLK1_PLK1_ST	O95613	PCNT	P53350	PLK1	T78	S74L	74	Missense	distal	-4	no	12.201	12.007	EPSD	TCGA;ICGC;COSMIC	10.919	Down-regulation
Other_PLK_PLK1_PLK1_ST	O95613	PCNT	P53350	PLK1	T78	G84W	84	Missense	distal	6	no	12.201	12.119	EPSD	TCGA;ICGC;COSMIC	10.919	Down-regulation
Other_PLK_PLK1_PLK1_ST	O95613	PCNT	P53350	PLK1	T186	V187F	187	Missense	proximal	1	no	10.077	11.557	EPSD	TCGA;ICGC;COSMIC	10.919	Gain
Other_PLK_PLK1_PLK1_ST	O95613	PCNT	P53350	PLK1	T191	I197M	197	Missense	distal	6	no	11.769	11.513	EPSD	TCGA;ICGC;COSMIC	10.919	Down-regulation
Other_PLK_PLK1_PLK1_ST	O95613	PCNT	P53350	PLK1	T191	V187F	187	Missense	distal	-4	no	11.769	11.551	EPSD	TCGA;ICGC;COSMIC	10.919	Down-regulation
Other_PLK_PLK1_PLK1_ST	O95613	PCNT	P53350	PLK1	T191	R195C	195	Missense	distal	4	no	11.769	12.187	EPSD	TCGA;ICGC	10.919	Up-regulation
Other_PLK_PLK1_PLK1_ST	O95613	PCNT	P53350	PLK1	T191	S188N	188	Missense	distal	-3	no	11.769	11.958	EPSD	TCGA;ICGC;COSMIC	10.919	Up-regulation
Other_PLK_PLK1_PLK1_ST	O95613	PCNT	P53350	PLK1	T191	T186A	186	Missense	distal	-5	no	11.769	11.838	EPSD	TCGA;ICGC	10.919	Up-regulation
Other_PLK_PLK1_PLK1_ST	O95613	PCNT	P53350	PLK1	T495	R497S	497	Missense	proximal	2	no	10.244	10.972	EPSD	TCGA;ICGC;COSMIC	10.919	Gain
Other_PLK_PLK1_PLK1_ST	O95613	PCNT	P53350	PLK1	S813	T815A	815	Missense	proximal	2	no	10.646	11.047	EPSD	TCGA;ICGC;COSMIC	10.919	Gain
Other_PLK_PLK1_PLK1_ST	O95613	PCNT	P53350	PLK1	S813	T815M	815	Missense	proximal	2	no	10.646	11.284	EPSD	TCGA;ICGC;COSMIC	10.919	Gain
Other_PLK_PLK1_PLK1_ST	O95613	PCNT	P53350	PLK1	T829	D827N	827	Missense	proximal	-2	no	11.371	10.129	EPSD	TCGA;ICGC;COSMIC	10.919	Loss
Other_PLK_PLK1_PLK1_ST	O95613	PCNT	P53350	PLK1	T829	S830P	830	Missense	proximal	1	no	11.371	12.493	EPSD	TCGA;ICGC;COSMIC	10.919	Up-regulation
Other_PLK_PLK1_PLK1_ST	O95613	PCNT	P53350	PLK1	S1006	W1002C	1002	Missense	distal	-4	no	13.306	12.646	EPSD	TCGA;ICGC;COSMIC	10.919	Down-regulation
Other_PLK_PLK1_PLK1_ST	O95613	PCNT	P53350	PLK1	S1006	S1006Y	1006	Missense	central	0	yes	13.306	0.000	EPSD	TCGA;ICGC	10.919	Loss
Other_PLK_PLK1_PLK1_ST	O95613	PCNT	P53350	PLK1	T1209	D1212H	1212	Missense	distal	3	no	12.997	12.759	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	10.919	Down-regulation
Other_PLK_PLK1_PLK1_ST	O95613	PCNT	P53350	PLK1	T1209	P1204L	1204	Missense	distal	-5	no	12.997	13.399	EPSD;PhosphoSitePlus	TCGA;ICGC	10.919	Up-regulation
Other_PLK_PLK1_PLK1_ST	O95613	PCNT	P53350	PLK1	T1221	M1228I	1228	Missense	distal	7	no	14.108	14.071	PhosphoSitePlus;EPSD	TCGA;ICGC	10.919	Down-regulation
Other_PLK_PLK1_PLK1_ST	O95613	PCNT	P53350	PLK1	S1235	R1239C	1239	Missense	distal	4	no	10.566	10.984	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	10.919	Gain
Other_PLK_PLK1_PLK1_ST	O95613	PCNT	P53350	PLK1	S1296	R1290C	1290	Missense	distal	-6	no	12.290	11.534	EPSD	TCGA;ICGC;COSMIC	10.919	Down-regulation
Other_PLK_PLK1_PLK1_ST	O95613	PCNT	P53350	PLK1	S1296	E1292A	1292	Missense	distal	-4	no	12.290	12.339	EPSD	TCGA;ICGC;COSMIC	10.919	Up-regulation
Other_PLK_PLK1_PLK1_ST	O95613	PCNT	P53350	PLK1	S1296	F1297V	1297	Missense	proximal	1	no	12.290	10.810	EPSD	TCGA;ICGC	10.919	Loss
Other_PLK_PLK1_PLK1_ST	O95613	PCNT	P53350	PLK1	T1702	N1701Y	1701	Missense	proximal	-1	no	10.980	11.456	EPSD	TCGA;ICGC;COSMIC	10.919	Up-regulation
Other_PLK_PLK1_PLK1_ST	O95613	PCNT	P53350	PLK1	S1764	P1758S	1758	Missense	distal	-6	no	10.425	11.048	EPSD	TCGA;ICGC;COSMIC	10.919	Gain
Other_PLK_PLK1_PLK1_ST	O95613	PCNT	P53350	PLK1	S1764	P1758H	1758	Missense	distal	-6	no	10.425	11.060	EPSD	TCGA;ICGC;COSMIC	10.919	Gain
Other_PLK_PLK1_PLK1_ST	O95613	PCNT	P53350	PLK1	T2085	Y2082C	2082	Missense	distal	-3	no	13.562	13.129	EPSD	TCGA;ICGC;COSMIC	10.919	Down-regulation
Other_PLK_PLK1_PLK1_ST	O95613	PCNT	P53350	PLK1	T2085	M2084L	2084	Missense	proximal	-1	no	13.562	13.031	EPSD	TCGA;ICGC;COSMIC	10.919	Down-regulation
Other_PLK_PLK1_PLK1_ST	O95613	PCNT	P53350	PLK1	S2114	S2114F	2114	Missense	central	0	yes	13.884	0.000	EPSD	TCGA;ICGC;COSMIC	10.919	Loss
Other_PLK_PLK1_PLK1_ST	O95613	PCNT	P53350	PLK1	S2114	S2108I	2108	Missense	distal	-6	no	13.884	13.953	EPSD	TCGA;ICGC;COSMIC	10.919	Up-regulation
Other_PLK_PLK1_PLK1_ST	O95613	PCNT	P53350	PLK1	S2114	G2117R	2117	Missense	distal	3	no	13.884	13.757	EPSD	TCGA;ICGC	10.919	Down-regulation
Other_PLK_PLK1_PLK1_ST	O95613	PCNT	P53350	PLK1	S2183	D2176H	2176	Missense	distal	-7	no	12.264	12.497	EPSD	TCGA;ICGC;COSMIC	10.919	Up-regulation
Other_PLK_PLK1_PLK1_ST	O95613	PCNT	P53350	PLK1	S2339	G2344S	2344	Missense	distal	5	no	11.355	11.172	EPSD	TCGA;ICGC;COSMIC;GDSC;CCLE	10.919	Down-regulation
Other_PLK_PLK1_PLK1_ST	O95613	PCNT	P53350	PLK1	S2372	P2379T	2379	Missense	distal	7	no	11.707	11.665	EPSD	TCGA;ICGC;COSMIC	10.919	Down-regulation
Other_PLK_PLK1_PLK1_ST	O95613	PCNT	P53350	PLK1	S2372	P2379Q	2379	Missense	distal	7	no	11.707	11.710	EPSD	TCGA;ICGC;COSMIC	10.919	Up-regulation
Other_PLK_PLK1_PLK1_ST	O95613	PCNT	P53350	PLK1	S2372	P2377S	2377	Missense	distal	5	no	11.707	11.320	EPSD	TCGA;ICGC;COSMIC	10.919	Down-regulation
Other_PLK_PLK1_PLK1_ST	O95613	PCNT	P53350	PLK1	S2372	P2368S	2368	Missense	distal	-4	no	11.707	11.829	EPSD	TCGA;ICGC;COSMIC	10.919	Up-regulation
Other_PLK_PLK1_PLK1_ST	O95613	PCNT	P53350	PLK1	S2372	S2372C	2372	Missense	central	0	yes	11.707	0.000	EPSD	TCGA;ICGC;COSMIC	10.919	Loss
Other_PLK_PLK1_PLK1_ST	O95613	PCNT	P53350	PLK1	S2433	E2428K	2428	Missense	distal	-5	no	11.190	11.433	EPSD	TCGA;ICGC	10.919	Up-regulation
Other_PLK_PLK1_PLK1_ST	O95613	PCNT	P53350	PLK1	S2433	D2427G	2427	Missense	distal	-6	no	11.190	10.727	EPSD	TCGA;ICGC;COSMIC	10.919	Loss
Other_PLK_PLK1_PLK1_ST	O95613	PCNT	P53350	PLK1	S2485	S2486F	2486	Missense	proximal	1	no	10.346	13.394	EPSD	TCGA;ICGC;COSMIC	10.919	Gain
Other_PLK_PLK1_PLK1_ST	O95613	PCNT	P53350	PLK1	S2486	S2486F	2486	Missense	central	0	yes	13.516	0.000	EPSD	TCGA;ICGC;COSMIC	10.919	Loss
Other_PLK_PLK1_PLK1_ST	O95613	PCNT	P53350	PLK1	S2515	D2513G	2513	Missense	proximal	-2	no	12.487	9.165	EPSD	TCGA;ICGC;COSMIC	10.919	Loss
Other_PLK_PLK1_PLK1_ST	O95613	PCNT	P53350	PLK1	T2584	S2586N	2586	Missense	proximal	2	no	10.885	11.098	EPSD	TCGA;ICGC;COSMIC	10.919	Gain
Other_PLK_PLK1_PLK1_ST	O95613	PCNT	P53350	PLK1	T2604	A2600V	2600	Missense	distal	-4	no	11.589	11.448	EPSD	TCGA;ICGC;COSMIC	10.919	Down-regulation
Other_PLK_PLK1_PLK1_ST	O95613	PCNT	P53350	PLK1	T2604	A2601E	2601	Missense	distal	-3	no	11.589	10.897	EPSD	TCGA;ICGC;COSMIC	10.919	Loss
Other_PLK_PLK1_PLK1_ST	O95613	PCNT	P53350	PLK1	S2860	E2864G	2864	Missense	distal	4	no	11.426	11.352	EPSD	TCGA;ICGC;COSMIC;GDSC;CCLE	10.919	Down-regulation
Other_PLK_PLK1_PLK1_ST	O95613	PCNT	P53350	PLK1	S2860	R2863T	2863	Missense	distal	3	no	11.426	11.413	EPSD	TCGA;ICGC;COSMIC	10.919	Down-regulation
Other_PLK_PLK1_PLK1_ST	O95613	PCNT	P53350	PLK1	S2900	A2895T	2895	Missense	distal	-5	no	11.419	11.350	EPSD	TCGA;ICGC;COSMIC	10.919	Down-regulation
Other_PLK_PLK1_PLK1_ST	O95613	PCNT	P53350	PLK1	T3000	V2997M	2997	Missense	distal	-3	no	10.900	11.028	EPSD	TCGA;ICGC;COSMIC;GDSC;CCLE	10.919	Gain
Other_PLK_PLK1_PLK1_ST	O95613	PCNT	P53350	PLK1	S3060	T3061M	3061	Missense	proximal	1	no	10.084	12.216	EPSD	TCGA;ICGC;COSMIC	10.919	Gain
Other_PLK_PLK1_PLK1_ST	O95613	PCNT	P53350	PLK1	S3070	V3073M	3073	Missense	distal	3	no	11.391	10.950	EPSD	TCGA;ICGC;COSMIC	10.919	Down-regulation
Other_PLK_PLK1_PLK1_ST	O95613	PCNT	P53350	PLK1	S3070	R3071G	3071	Missense	proximal	1	no	11.391	13.492	EPSD	TCGA;ICGC;COSMIC	10.919	Up-regulation
Other_PLK_PLK1_PLK1_ST	O95613	PCNT	P53350	PLK1	S3074	V3073M	3073	Missense	proximal	-1	no	11.095	12.123	EPSD	TCGA;ICGC;COSMIC	10.919	Up-regulation
Other_PLK_PLK1_PLK1_ST	O95613	PCNT	P53350	PLK1	S3074	L3080Q	3080	Missense	distal	6	no	11.095	11.036	EPSD	TCGA;ICGC;COSMIC	10.919	Down-regulation
Other_PLK_PLK1_PLK1_ST	O95613	PCNT	P53350	PLK1	S3074	R3071G	3071	Missense	distal	-3	no	11.095	11.036	EPSD	TCGA;ICGC;COSMIC	10.919	Down-regulation
Other_PLK_PLK1_PLK1_ST	O95613	PCNT	P53350	PLK1	S3324	T3325A	3325	Missense	proximal	1	no	11.678	11.215	EPSD	TCGA;ICGC;COSMIC	10.919	Down-regulation
Other_PLK_PLK1_PLK1_ST	P30307	CDC25C	P53350	PLK1	S38	D36Y	36	Missense	proximal	-2	no	12.316	10.775	EPSD	TCGA;ICGC	10.919	Loss
Other_PLK_PLK1_PLK1_ST	P30307	CDC25C	P53350	PLK1	S75	E81D	81	Missense	distal	6	no	12.138	12.287	PhosphoSitePlus;EPSD	TCGA;ICGC;COSMIC	10.919	Up-regulation
Other_PLK_PLK1_PLK1_ST	P30307	CDC25C	P53350	PLK1	S75	L77R	77	Missense	proximal	2	no	12.138	11.338	PhosphoSitePlus;EPSD	TCGA;ICGC;COSMIC	10.919	Down-regulation
Other_PLK_PLK1_PLK1_ST	P30307	CDC25C	P53350	PLK1	S75	S75L	75	Missense	central	0	yes	12.138	0.000	PhosphoSitePlus;EPSD	TCGA;ICGC;COSMIC	10.919	Loss
Other_PLK_PLK1_PLK1_ST	P30307	CDC25C	P53350	PLK1	S75	D73N	73	Missense	proximal	-2	no	12.138	10.895	PhosphoSitePlus;EPSD	TCGA;ICGC;COSMIC	10.919	Loss
Other_PLK_PLK1_PLK1_ST	P30307	CDC25C	P53350	PLK1	S75	S79N	79	Missense	distal	4	no	12.138	11.902	PhosphoSitePlus;EPSD	TCGA;ICGC;COSMIC	10.919	Down-regulation
Other_PLK_PLK1_PLK1_ST	P30307	CDC25C	P53350	PLK1	T268	S263F	263	Missense	distal	-5	no	13.198	12.937	EPSD	TCGA;ICGC;COSMIC	10.919	Down-regulation
Other_PLK_PLK1_PLK1_ST	P30307	CDC25C	P53350	PLK1	S277	G280E	280	Missense	distal	3	no	12.100	12.277	EPSD	TCGA;ICGC;COSMIC	10.919	Up-regulation
Other_PLK_PLK1_PLK1_ST	P30307	CDC25C	P53350	PLK1	S277	S277C	277	Missense	central	0	yes	12.100	0.000	EPSD	TCGA;ICGC;COSMIC	10.919	Loss
Other_PLK_PLK1_PLK1_ST	P30307	CDC25C	P53350	PLK1	S277	N278K	278	Missense	proximal	1	no	12.100	11.600	EPSD	TCGA;ICGC;COSMIC	10.919	Down-regulation
Other_PLK_PLK1_PLK1_ST	O43663	PRC1	P53350	PLK1	S11	A8V	8	Missense	distal	-3	no	11.568	11.169	EPSD	TCGA;ICGC;COSMIC	10.919	Down-regulation
Other_PLK_PLK1_PLK1_ST	O43663	PRC1	P53350	PLK1	S11	A8T	8	Missense	distal	-3	no	11.568	11.422	EPSD	TCGA;ICGC;COSMIC	10.919	Down-regulation
Other_PLK_PLK1_PLK1_ST	O43663	PRC1	P53350	PLK1	S70	K67N	67	Missense	distal	-3	no	11.396	11.215	EPSD	TCGA;ICGC;COSMIC	10.919	Down-regulation
Other_PLK_PLK1_PLK1_ST	O43663	PRC1	P53350	PLK1	T327	Q332R	332	Missense	distal	5	no	10.208	11.004	EPSD	TCGA;ICGC;COSMIC	10.919	Gain
Other_PLK_PLK1_PLK1_ST	O43663	PRC1	P53350	PLK1	T491	T497M	497	Missense	distal	6	no	11.839	11.309	EPSD	TCGA;ICGC;COSMIC	10.919	Down-regulation
Other_PLK_PLK1_PLK1_ST	O43663	PRC1	P53350	PLK1	S500	R503W	503	Missense	distal	3	no	11.291	11.062	EPSD	TCGA;ICGC;COSMIC	10.919	Down-regulation
Other_PLK_PLK1_PLK1_ST	O43663	PRC1	P53350	PLK1	S500	T497M	497	Missense	distal	-3	no	11.291	11.166	EPSD	TCGA;ICGC;COSMIC	10.919	Down-regulation
Other_PLK_PLK1_PLK1_ST	O43663	PRC1	P53350	PLK1	S501	R503W	503	Missense	proximal	2	no	11.409	12.156	EPSD	TCGA;ICGC;COSMIC	10.919	Up-regulation
Other_PLK_PLK1_PLK1_ST	O43663	PRC1	P53350	PLK1	S501	T497M	497	Missense	distal	-4	no	11.409	11.495	EPSD	TCGA;ICGC;COSMIC	10.919	Up-regulation
Other_PLK_PLK1_PLK1_ST	O43663	PRC1	P53350	PLK1	S513	S516Y	516	Missense	distal	3	no	11.022	10.842	EPSD	TCGA;ICGC;COSMIC	10.919	Loss
Other_PLK_PLK1_PLK1_ST	O43663	PRC1	P53350	PLK1	S554	G558C	558	Missense	distal	4	no	11.834	11.393	EPSD	TCGA;ICGC;COSMIC;GDSC;CCLE	10.919	Down-regulation
Other_PLK_PLK1_PLK1_ST	O43663	PRC1	P53350	PLK1	S554	Y560C	560	Missense	distal	6	no	11.834	11.429	EPSD	TCGA;ICGC;COSMIC	10.919	Down-regulation
Other_PLK_PLK1_PLK1_ST	O43663	PRC1	P53350	PLK1	S587	P586S	586	Missense	proximal	-1	no	14.025	15.199	EPSD	TCGA;ICGC	10.919	Up-regulation
Other_PLK_PLK1_PLK1_ST	O43663	PRC1	P53350	PLK1	S601	D607H	607	Missense	distal	6	no	14.240	13.446	EPSD	TCGA;ICGC;COSMIC	10.919	Down-regulation
Other_PLK_PLK1_PLK1_ST	Q7L2Z9	CENPQ	P53350	PLK1	T135	K129N	129	Missense	distal	-6	no	11.453	11.711	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	10.919	Up-regulation
Other_PLK_PLK1_PLK1_ST	Q7L2Z9	CENPQ	P53350	PLK1	T135	D133N	133	Missense	proximal	-2	no	11.453	10.210	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	10.919	Loss
Other_PLK_PLK1_PLK1_ST	Q7L2Z9	CENPQ	P53350	PLK1	S138	D133N	133	Missense	distal	-5	no	12.249	11.953	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	10.919	Down-regulation
Other_PLK_PLK1_PLK1_ST	Q7L2Z9	CENPQ	P53350	PLK1	T169	E170K	170	Missense	proximal	1	no	10.970	10.520	EPSD	TCGA;ICGC	10.919	Loss
Other_PLK_PLK1_PLK1_ST	Q7L2Z9	CENPQ	P53350	PLK1	T169	V166A	166	Missense	distal	-3	no	10.970	11.369	EPSD	TCGA;ICGC;COSMIC	10.919	Up-regulation
Other_PLK_PLK1_PLK1_ST	Q7L2Z9	CENPQ	P53350	PLK1	T173	E170K	170	Missense	distal	-3	no	12.399	12.939	EPSD	TCGA;ICGC	10.919	Up-regulation
Other_PLK_PLK1_PLK1_ST	Q7L2Z9	CENPQ	P53350	PLK1	T173	K180Q	180	Missense	distal	7	no	12.399	12.379	EPSD	TCGA;ICGC;COSMIC	10.919	Down-regulation
Other_PLK_PLK1_PLK1_ST	Q7L2Z9	CENPQ	P53350	PLK1	T173	Q177H	177	Missense	distal	4	no	12.399	12.293	EPSD	TCGA;ICGC;COSMIC	10.919	Down-regulation
Other_PLK_PLK1_PLK1_ST	Q7L2Z9	CENPQ	P53350	PLK1	T173	V166A	166	Missense	distal	-7	no	12.399	12.342	EPSD	TCGA;ICGC;COSMIC	10.919	Down-regulation
Other_PLK_PLK1_PLK1_ST	Q7L2Z9	CENPQ	P53350	PLK1	S249	K252N	252	Missense	distal	3	no	14.494	14.566	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	10.919	Up-regulation
Other_PLK_PLK1_PLK1_ST	Q7L2Z9	CENPQ	P53350	PLK1	S249	M254V	254	Missense	distal	5	no	14.494	14.226	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	10.919	Down-regulation
Other_PLK_PLK1_PLK1_ST	Q7L2Z9	CENPQ	P53350	PLK1	S253	K252N	252	Missense	proximal	-1	no	12.568	13.002	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	10.919	Up-regulation
Other_PLK_PLK1_PLK1_ST	Q7L2Z9	CENPQ	P53350	PLK1	S253	M254V	254	Missense	proximal	1	no	12.568	11.412	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	10.919	Down-regulation
Other_PLK_PLK1_PLK1_ST	Q7L2Z9	CENPQ	P53350	PLK1	S255	K252N	252	Missense	distal	-3	no	11.102	10.921	PhosphoSitePlus;EPSD	TCGA;ICGC;COSMIC	10.919	Down-regulation
Other_PLK_PLK1_PLK1_ST	Q7L2Z9	CENPQ	P53350	PLK1	S255	M254V	254	Missense	proximal	-1	no	11.102	10.074	PhosphoSitePlus;EPSD	TCGA;ICGC;COSMIC	10.919	Loss
Other_PLK_PLK1_PLK1_ST	Q7L2Z9	CENPQ	P53350	PLK1	T256	K252N	252	Missense	distal	-4	no	14.680	14.938	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	10.919	Up-regulation
Other_PLK_PLK1_PLK1_ST	Q7L2Z9	CENPQ	P53350	PLK1	T256	M254V	254	Missense	proximal	-2	no	14.680	15.176	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	10.919	Up-regulation
Other_PLK_PLK1_PLK1_ST	Q8IZD2	KMT2E	P53350	PLK1	S265	I262S	262	Missense	distal	-3	no	12.689	12.289	EPSD	TCGA;ICGC;COSMIC	10.919	Down-regulation
Other_PLK_PLK1_PLK1_ST	Q8IZD2	KMT2E	P53350	PLK1	S265	S265L	265	Missense	central	0	yes	12.689	0.000	EPSD	TCGA;ICGC;COSMIC	10.919	Loss
Other_PLK_PLK1_PLK1_ST	Q8IZD2	KMT2E	P53350	PLK1	S499	Q505K	505	Missense	distal	6	no	12.233	12.305	EPSD	TCGA;ICGC;COSMIC	10.919	Up-regulation
Other_PLK_PLK1_PLK1_ST	Q8IZD2	KMT2E	P53350	PLK1	S499	D497Y	497	Missense	proximal	-2	no	12.233	10.692	EPSD	TCGA;ICGC;COSMIC	10.919	Loss
Other_PLK_PLK1_PLK1_ST	Q8IZD2	KMT2E	P53350	PLK1	S499	D503Y	503	Missense	distal	4	no	12.233	11.988	EPSD	TCGA;ICGC;COSMIC	10.919	Down-regulation
Other_PLK_PLK1_PLK1_ST	Q8IZD2	KMT2E	P53350	PLK1	S499	D495Y	495	Missense	distal	-4	no	12.233	11.740	EPSD	TCGA;ICGC	10.919	Down-regulation
Other_PLK_PLK1_PLK1_ST	Q8IZD2	KMT2E	P53350	PLK1	T510	Q507K	507	Missense	distal	-3	no	11.744	11.958	EPSD	TCGA	10.919	Up-regulation
Other_PLK_PLK1_PLK1_ST	Q8IZD2	KMT2E	P53350	PLK1	T510	Q505K	505	Missense	distal	-5	no	11.744	11.945	EPSD	TCGA;ICGC;COSMIC	10.919	Up-regulation
Other_PLK_PLK1_PLK1_ST	Q8IZD2	KMT2E	P53350	PLK1	T510	D503Y	503	Missense	distal	-7	no	11.744	11.482	EPSD	TCGA;ICGC;COSMIC	10.919	Down-regulation
Other_PLK_PLK1_PLK1_ST	Q8IZD2	KMT2E	P53350	PLK1	S538	V537I	537	Missense	proximal	-1	no	10.003	10.977	EPSD	TCGA;ICGC;COSMIC	10.919	Gain
Other_PLK_PLK1_PLK1_ST	Q8IZD2	KMT2E	P53350	PLK1	T553	I546V	546	Missense	distal	-7	no	11.458	11.624	EPSD	TCGA;ICGC	10.919	Up-regulation
Other_PLK_PLK1_PLK1_ST	Q8IZD2	KMT2E	P53350	PLK1	T553	K552T	552	Missense	proximal	-1	no	11.458	11.286	EPSD	TCGA;ICGC;COSMIC	10.919	Down-regulation
Other_PLK_PLK1_PLK1_ST	Q8IZD2	KMT2E	P53350	PLK1	T619	C616R	616	Missense	distal	-3	no	10.441	11.237	EPSD	TCGA;ICGC;COSMIC	10.919	Gain
Other_PLK_PLK1_PLK1_ST	Q8IZD2	KMT2E	P53350	PLK1	S780	S773C	773	Missense	distal	-7	no	11.472	10.855	EPSD	TCGA;ICGC;COSMIC	10.919	Loss
Other_PLK_PLK1_PLK1_ST	Q8IZD2	KMT2E	P53350	PLK1	S780	G776D	776	Missense	distal	-4	no	11.472	11.932	EPSD	TCGA;ICGC	10.919	Up-regulation
Other_PLK_PLK1_PLK1_ST	Q8IZD2	KMT2E	P53350	PLK1	S829	N828H	828	Missense	proximal	-1	no	11.883	12.084	EPSD	TCGA;ICGC;COSMIC	10.919	Up-regulation
Other_PLK_PLK1_PLK1_ST	Q8IZD2	KMT2E	P53350	PLK1	S909	D902N	902	Missense	distal	-7	no	15.640	15.780	EPSD	TCGA;ICGC;COSMIC	10.919	Up-regulation
Other_PLK_PLK1_PLK1_ST	Q8IZD2	KMT2E	P53350	PLK1	S909	S909C	909	Missense	central	0	yes	15.640	0.000	EPSD	TCGA;ICGC;COSMIC	10.919	Loss
Other_PLK_PLK1_PLK1_ST	Q8IZD2	KMT2E	P53350	PLK1	S909	R915W	915	Missense	distal	6	no	15.640	15.660	EPSD	TCGA;ICGC;COSMIC	10.919	Up-regulation
Other_PLK_PLK1_PLK1_ST	Q8IZD2	KMT2E	P53350	PLK1	S909	S909F	909	Missense	central	0	yes	15.640	0.000	EPSD	TCGA;ICGC;COSMIC	10.919	Loss
Other_PLK_PLK1_PLK1_ST	Q8IZD2	KMT2E	P53350	PLK1	S966	I960L	960	Missense	distal	-6	no	11.434	11.031	EPSD	TCGA;ICGC;COSMIC	10.919	Down-regulation
Other_PLK_PLK1_PLK1_ST	Q8IZD2	KMT2E	P53350	PLK1	S966	R963H	963	Missense	distal	-3	no	11.434	10.762	EPSD	TCGA;ICGC;COSMIC;GDSC;CCLE	10.919	Loss
Other_PLK_PLK1_PLK1_ST	Q8IZD2	KMT2E	P53350	PLK1	T1062	G1061D	1061	Missense	proximal	-1	no	11.152	13.741	EPSD	TCGA;ICGC	10.919	Up-regulation
Other_PLK_PLK1_PLK1_ST	Q8IZD2	KMT2E	P53350	PLK1	S1066	G1061D	1061	Missense	distal	-5	no	11.645	11.490	EPSD	TCGA;ICGC	10.919	Down-regulation
Other_PLK_PLK1_PLK1_ST	Q8IZD2	KMT2E	P53350	PLK1	T1088	T1088I	1088	Missense	central	0	yes	11.129	0.000	EPSD	TCGA;ICGC;COSMIC	10.919	Loss
Other_PLK_PLK1_PLK1_ST	Q8IZD2	KMT2E	P53350	PLK1	T1088	D1086V	1086	Missense	proximal	-2	no	11.129	8.517	EPSD	TCGA;ICGC;COSMIC	10.919	Loss
Other_PLK_PLK1_PLK1_ST	Q8IZD2	KMT2E	P53350	PLK1	T1088	R1085K	1085	Missense	distal	-3	no	11.129	10.668	EPSD	TCGA;ICGC;COSMIC	10.919	Loss
Other_PLK_PLK1_PLK1_ST	Q8IZD2	KMT2E	P53350	PLK1	S1285	D1278H	1278	Missense	distal	-7	no	10.953	11.186	EPSD	TCGA;ICGC;COSMIC	10.919	Up-regulation
Other_PLK_PLK1_PLK1_ST	Q8IZD2	KMT2E	P53350	PLK1	S1344	N1346S	1346	Missense	proximal	2	no	11.998	11.785	EPSD	TCGA;COSMIC	10.919	Down-regulation
Other_PLK_PLK1_PLK1_ST	Q8IZD2	KMT2E	P53350	PLK1	S1344	S1340F	1340	Missense	distal	-4	no	11.998	11.680	EPSD	TCGA;COSMIC	10.919	Down-regulation
Other_PLK_PLK1_PLK1_ST	Q8IZD2	KMT2E	P53350	PLK1	S1405	E1398D	1398	Missense	distal	-7	no	11.614	11.325	EPSD	TCGA;COSMIC	10.919	Down-regulation
Other_PLK_PLK1_PLK1_ST	Q9Y6D9	MAD1L1	P53350	PLK1	T8	E6K	6	Missense	proximal	-2	no	12.736	9.859	EPSD	TCGA;ICGC;COSMIC	10.919	Loss
Other_PLK_PLK1_PLK1_ST	Q9Y6D9	MAD1L1	P53350	PLK1	S22	R24L	24	Missense	proximal	2	no	10.339	11.138	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	10.919	Gain
Other_PLK_PLK1_PLK1_ST	Q9Y6D9	MAD1L1	P53350	PLK1	S266	A267V	267	Missense	proximal	1	no	10.848	12.286	EPSD	TCGA;COSMIC	10.919	Gain
Other_PLK_PLK1_PLK1_ST	Q9Y6D9	MAD1L1	P53350	PLK1	S420	I414T	414	Missense	distal	-6	no	13.823	13.651	EPSD	TCGA;COSMIC	10.919	Down-regulation
Other_PLK_PLK1_PLK1_ST	Q9Y6D9	MAD1L1	P53350	PLK1	S428	Q430H	430	Missense	proximal	2	no	13.971	14.349	EPSD	TCGA;COSMIC	10.919	Up-regulation
Other_PLK_PLK1_PLK1_ST	Q9Y6D9	MAD1L1	P53350	PLK1	S447	E451K	451	Missense	distal	4	no	11.041	10.668	EPSD	TCGA	10.919	Loss
Other_PLK_PLK1_PLK1_ST	Q9Y6D9	MAD1L1	P53350	PLK1	S490	E496V	496	Missense	distal	6	no	14.341	14.327	EPSD	TCGA;COSMIC	10.919	Down-regulation
Other_PLK_PLK1_PLK1_ST	Q9Y6D9	MAD1L1	P53350	PLK1	S490	E488K	488	Missense	proximal	-2	no	14.341	11.464	EPSD	TCGA;COSMIC	10.919	Down-regulation
Other_PLK_PLK1_PLK1_ST	Q9Y6D9	MAD1L1	P53350	PLK1	S490	S490G	490	Missense	central	0	yes	14.341	0.000	EPSD	TCGA;COSMIC	10.919	Loss
Other_PLK_PLK1_PLK1_ST	Q9Y6D9	MAD1L1	P53350	PLK1	S546	N548D	548	Missense	proximal	2	no	13.046	12.831	EPSD	TCGA;COSMIC	10.919	Down-regulation
Other_PLK_PLK1_PLK1_ST	Q9Y6D9	MAD1L1	P53350	PLK1	S562	R556C	556	Missense	distal	-6	no	10.942	10.186	EPSD	TCGA;COSMIC;CCLE	10.919	Loss
Other_PLK_PLK1_PLK1_ST	Q9Y6D9	MAD1L1	P53350	PLK1	S562	R556H	556	Missense	distal	-6	no	10.942	11.401	EPSD	TCGA;COSMIC	10.919	Up-regulation
Other_PLK_PLK1_PLK1_ST	Q9Y6D9	MAD1L1	P53350	PLK1	S699	R695Q	695	Missense	distal	-4	no	10.982	11.270	EPSD	TCGA;COSMIC	10.919	Up-regulation
Other_PLK_PLK1_PLK1_ST	Q9Y6D9	MAD1L1	P53350	PLK1	S699	R696C	696	Missense	distal	-3	no	10.982	10.186	EPSD	TCGA;COSMIC	10.919	Loss
Other_PLK_PLK1_PLK1_ST	Q99708	RBBP8	P53350	PLK1	S17	S13C	13	Missense	distal	-4	no	12.525	11.713	EPSD	TCGA;ICGC;COSMIC	10.919	Down-regulation
Other_PLK_PLK1_PLK1_ST	Q99708	RBBP8	P53350	PLK1	S17	N12K	12	Missense	distal	-5	no	12.525	12.723	EPSD	TCGA;ICGC;COSMIC	10.919	Up-regulation
Other_PLK_PLK1_PLK1_ST	Q99708	RBBP8	P53350	PLK1	S17	A14V	14	Missense	distal	-3	no	12.525	12.126	EPSD	TCGA;ICGC;COSMIC	10.919	Down-regulation
Other_PLK_PLK1_PLK1_ST	Q99708	RBBP8	P53350	PLK1	S249	P246L	246	Missense	distal	-3	no	10.534	11.726	EPSD	TCGA;ICGC;COSMIC	10.919	Gain
Other_PLK_PLK1_PLK1_ST	Q99708	RBBP8	P53350	PLK1	S269	M275L	275	Missense	distal	6	no	10.885	11.179	EPSD	TCGA;ICGC;COSMIC	10.919	Gain
Other_PLK_PLK1_PLK1_ST	Q99708	RBBP8	P53350	PLK1	S276	M275L	275	Missense	proximal	-1	no	11.817	11.286	EPSD	TCGA;ICGC;COSMIC	10.919	Down-regulation
Other_PLK_PLK1_PLK1_ST	Q99708	RBBP8	P53350	PLK1	S276	P274L	274	Missense	proximal	-2	no	11.817	11.454	EPSD	TCGA;ICGC;COSMIC	10.919	Down-regulation
Other_PLK_PLK1_PLK1_ST	Q99708	RBBP8	P53350	PLK1	S345	S347F	347	Missense	proximal	2	no	12.648	12.097	EPSD	TCGA;ICGC;COSMIC	10.919	Down-regulation
Other_PLK_PLK1_PLK1_ST	Q99708	RBBP8	P53350	PLK1	S349	S347F	347	Missense	proximal	-2	no	11.566	10.009	EPSD	TCGA;ICGC;COSMIC	10.919	Loss
Other_PLK_PLK1_PLK1_ST	Q99708	RBBP8	P53350	PLK1	S454	E451K	451	Missense	distal	-3	no	10.691	11.231	EPSD	TCGA;ICGC;COSMIC	10.919	Gain
Other_PLK_PLK1_PLK1_ST	Q99708	RBBP8	P53350	PLK1	S649	E651Q	651	Missense	proximal	2	no	11.567	11.756	EPSD	TCGA;ICGC;COSMIC	10.919	Up-regulation
Other_PLK_PLK1_PLK1_ST	Q99708	RBBP8	P53350	PLK1	S664	V670I	670	Missense	distal	6	no	14.730	14.624	EPSD	TCGA;ICGC	10.919	Down-regulation
Other_PLK_PLK1_PLK1_ST	Q99708	RBBP8	P53350	PLK1	S664	D658Y	658	Missense	distal	-6	no	14.730	13.961	EPSD	TCGA;ICGC;COSMIC	10.919	Down-regulation
Other_PLK_PLK1_PLK1_ST	Q99708	RBBP8	P53350	PLK1	S723	K719Q	719	Missense	distal	-4	no	11.967	12.082	PhosphoSitePlus;EPSD	TCGA;COSMIC	10.919	Up-regulation
Other_PLK_PLK1_PLK1_ST	Q99708	RBBP8	P53350	PLK1	S789	H795D	795	Missense	distal	6	no	11.693	12.487	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	10.919	Up-regulation
Other_PLK_PLK1_PLK1_ST	Q15022	SUZ12	P53350	PLK1	S384	L377F	377	Missense	distal	-7	no	12.886	12.734	EPSD	TCGA;ICGC;COSMIC	10.919	Down-regulation
Other_PLK_PLK1_PLK1_ST	Q15022	SUZ12	P53350	PLK1	S384	E383K	383	Missense	proximal	-1	no	12.886	12.315	EPSD	TCGA;ICGC;COSMIC	10.919	Down-regulation
Other_PLK_PLK1_PLK1_ST	Q15022	SUZ12	P53350	PLK1	S384	S384N	384	Missense	central	0	yes	12.886	0.000	EPSD	TCGA;ICGC;COSMIC	10.919	Loss
Other_PLK_PLK1_PLK1_ST	Q15022	SUZ12	P53350	PLK1	S462	K468N	468	Missense	distal	6	no	11.249	11.248	EPSD	TCGA;ICGC;COSMIC	10.919	Down-regulation
Other_PLK_PLK1_PLK1_ST	Q15022	SUZ12	P53350	PLK1	S462	K459E	459	Missense	distal	-3	no	11.249	10.709	EPSD	TCGA;ICGC;COSMIC	10.919	Loss
Other_PLK_PLK1_PLK1_ST	Q15022	SUZ12	P53350	PLK1	S462	L455M	455	Missense	distal	-7	no	11.249	11.124	EPSD	TCGA;ICGC;COSMIC	10.919	Down-regulation
Other_PLK_PLK1_PLK1_ST	Q15022	SUZ12	P53350	PLK1	S539	R532M	532	Missense	distal	-7	no	11.510	11.577	EPSD;PhosphoSitePlus	TCGA;COSMIC	10.919	Up-regulation
Other_PLK_PLK1_PLK1_ST	Q15022	SUZ12	P53350	PLK1	S539	R535Q	535	Missense	distal	-4	no	11.510	11.798	EPSD;PhosphoSitePlus	TCGA;ICGC	10.919	Up-regulation
Other_PLK_PLK1_PLK1_ST	Q15022	SUZ12	P53350	PLK1	S604	E601Q	601	Missense	distal	-3	no	11.616	11.942	EPSD	TCGA;ICGC;COSMIC	10.919	Up-regulation
Other_PLK_PLK1_PLK1_ST	Q15022	SUZ12	P53350	PLK1	S604	S604C	604	Missense	central	0	yes	11.616	0.000	EPSD	TCGA;ICGC;COSMIC	10.919	Loss
Other_PLK_PLK1_PLK1_ST	Q15022	SUZ12	P53350	PLK1	S604	E610G	610	Missense	distal	6	no	11.616	11.290	EPSD	TCGA;COSMIC	10.919	Down-regulation
Other_PLK_PLK1_PLK1_ST	Q15022	SUZ12	P53350	PLK1	S604	I597V	597	Missense	distal	-7	no	11.616	11.781	EPSD	TCGA;ICGC;COSMIC	10.919	Up-regulation
Other_PLK_PLK1_PLK1_ST	Q15022	SUZ12	P53350	PLK1	S726	D725Y	725	Missense	proximal	-1	no	13.282	12.826	EPSD	TCGA;COSMIC	10.919	Down-regulation
Other_PLK_PLK1_PLK1_ST	Q9BVS4	RIOK2	P53350	PLK1	S36	L37F	37	Missense	proximal	1	no	10.680	11.761	EPSD	TCGA	10.919	Gain
Other_PLK_PLK1_PLK1_ST	Q9BVS4	RIOK2	P53350	PLK1	S36	V33A	33	Missense	distal	-3	no	10.680	11.079	EPSD	TCGA;ICGC	10.919	Gain
Other_PLK_PLK1_PLK1_ST	Q9BVS4	RIOK2	P53350	PLK1	S131	R126K	126	Missense	distal	-5	no	11.981	11.442	EPSD	TCGA;ICGC;COSMIC	10.919	Down-regulation
Other_PLK_PLK1_PLK1_ST	Q9BVS4	RIOK2	P53350	PLK1	S131	R129K	129	Missense	proximal	-2	no	11.981	11.587	EPSD	TCGA;ICGC;COSMIC	10.919	Down-regulation
Other_PLK_PLK1_PLK1_ST	Q9BVS4	RIOK2	P53350	PLK1	S332	G331R	331	Missense	proximal	-1	no	10.404	11.264	EPSD	TCGA;ICGC;COSMIC	10.919	Gain
Other_PLK_PLK1_PLK1_ST	Q9BVS4	RIOK2	P53350	PLK1	S332	F334L	334	Missense	proximal	2	no	10.404	11.026	EPSD	TCGA;ICGC;COSMIC	10.919	Gain
Other_PLK_PLK1_PLK1_ST	Q9BVS4	RIOK2	P53350	PLK1	S335	E330Q	330	Missense	distal	-5	no	14.806	14.849	PhosphoSitePlus;EPSD	TCGA;ICGC;COSMIC	10.919	Up-regulation
Other_PLK_PLK1_PLK1_ST	Q9BVS4	RIOK2	P53350	PLK1	S335	D338N	338	Missense	distal	3	no	14.806	14.606	PhosphoSitePlus;EPSD	TCGA	10.919	Down-regulation
Other_PLK_PLK1_PLK1_ST	Q9BVS4	RIOK2	P53350	PLK1	S335	G331R	331	Missense	distal	-4	no	14.806	14.894	PhosphoSitePlus;EPSD	TCGA;ICGC;COSMIC	10.919	Up-regulation
Other_PLK_PLK1_PLK1_ST	Q9BVS4	RIOK2	P53350	PLK1	S335	A342T	342	Missense	distal	7	no	14.806	14.766	PhosphoSitePlus;EPSD	TCGA;ICGC;COSMIC	10.919	Down-regulation
Other_PLK_PLK1_PLK1_ST	Q9BVS4	RIOK2	P53350	PLK1	S335	S335L	335	Missense	central	0	yes	14.806	0.000	PhosphoSitePlus;EPSD	TCGA;ICGC;COSMIC;GDSC;CCLE	10.919	Loss
Other_PLK_PLK1_PLK1_ST	Q9BVS4	RIOK2	P53350	PLK1	S335	F334L	334	Missense	proximal	-1	no	14.806	14.885	PhosphoSitePlus;EPSD	TCGA;ICGC;COSMIC	10.919	Up-regulation
Other_PLK_PLK1_PLK1_ST	Q9BVS4	RIOK2	P53350	PLK1	S380	E383Q	383	Missense	distal	3	no	14.193	14.085	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	10.919	Down-regulation
Other_PLK_PLK1_PLK1_ST	Q9BVS4	RIOK2	P53350	PLK1	S380	L381V	381	Missense	proximal	1	no	14.193	13.794	EPSD;PhosphoSitePlus	TCGA;ICGC	10.919	Down-regulation
Other_PLK_PLK1_PLK1_ST	Q9BVS4	RIOK2	P53350	PLK1	S457	H451R	451	Missense	distal	-6	no	12.037	11.578	EPSD	TCGA;ICGC;COSMIC	10.919	Down-regulation
Other_PLK_PLK1_PLK1_ST	Q9BVS4	RIOK2	P53350	PLK1	S457	S456P	456	Missense	proximal	-1	no	12.037	10.863	EPSD	TCGA;ICGC;COSMIC	10.919	Loss
Other_PLK_PLK1_PLK1_ST	Q9BVS4	RIOK2	P53350	PLK1	S457	S456L	456	Missense	proximal	-1	no	12.037	11.577	EPSD	TCGA;ICGC;COSMIC;GDSC;CCLE	10.919	Down-regulation
Other_PLK_PLK1_PLK1_ST	Q9BVS4	RIOK2	P53350	PLK1	S457	A454D	454	Missense	distal	-3	no	12.037	11.805	EPSD	TCGA;ICGC;COSMIC	10.919	Down-regulation
Other_PLK_PLK1_PLK1_ST	Q9BVS4	RIOK2	P53350	PLK1	S457	E461Q	461	Missense	distal	4	no	12.037	11.633	EPSD	TCGA;ICGC;COSMIC	10.919	Down-regulation
Other_PLK_PLK1_PLK1_ST	Q9BVS4	RIOK2	P53350	PLK1	S548	A547V	547	Missense	proximal	-1	no	12.055	11.565	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	10.919	Down-regulation
Other_PLK_PLK1_PLK1_ST	Q14676	MDC1	P53350	PLK1	S292	V287A	287	Missense	distal	-5	no	10.929	11.002	EPSD	TCGA;ICGC;COSMIC	10.919	Up-regulation
Other_PLK_PLK1_PLK1_ST	Q14676	MDC1	P53350	PLK1	S299	T301I	301	Missense	proximal	2	no	11.763	12.825	EPSD	TCGA;ICGC;COSMIC	10.919	Up-regulation
Other_PLK_PLK1_PLK1_ST	Q14676	MDC1	P53350	PLK1	S299	D302Y	302	Missense	distal	3	no	11.763	11.337	EPSD	TCGA;ICGC;COSMIC	10.919	Down-regulation
Other_PLK_PLK1_PLK1_ST	Q14676	MDC1	P53350	PLK1	S372	D377H	377	Missense	distal	5	no	11.301	10.846	EPSD	TCGA;ICGC;COSMIC	10.919	Loss
Other_PLK_PLK1_PLK1_ST	Q14676	MDC1	P53350	PLK1	S372	A374V	374	Missense	proximal	2	no	11.301	11.745	EPSD	TCGA;ICGC	10.919	Up-regulation
Other_PLK_PLK1_PLK1_ST	Q14676	MDC1	P53350	PLK1	S372	A367V	367	Missense	distal	-5	no	11.301	11.229	EPSD	TCGA;ICGC;COSMIC	10.919	Down-regulation
Other_PLK_PLK1_PLK1_ST	Q14676	MDC1	P53350	PLK1	T378	D377H	377	Missense	proximal	-1	no	13.390	12.658	EPSD	TCGA;ICGC;COSMIC	10.919	Down-regulation
Other_PLK_PLK1_PLK1_ST	Q14676	MDC1	P53350	PLK1	T378	S372T	372	Missense	distal	-6	no	13.390	13.287	EPSD	TCGA;ICGC;COSMIC	10.919	Down-regulation
Other_PLK_PLK1_PLK1_ST	Q14676	MDC1	P53350	PLK1	T378	A374V	374	Missense	distal	-4	no	13.390	13.250	EPSD	TCGA;ICGC	10.919	Down-regulation
Other_PLK_PLK1_PLK1_ST	Q14676	MDC1	P53350	PLK1	S394	K393E	393	Missense	proximal	-1	no	13.136	13.707	EPSD	TCGA	10.919	Up-regulation
Other_PLK_PLK1_PLK1_ST	Q14676	MDC1	P53350	PLK1	S394	S397F	397	Missense	distal	3	no	13.136	13.196	EPSD	TCGA;ICGC	10.919	Up-regulation
Other_PLK_PLK1_PLK1_ST	Q14676	MDC1	P53350	PLK1	S485	A479T	479	Missense	distal	-6	no	10.999	10.932	EPSD	TCGA;ICGC;COSMIC	10.919	Down-regulation
Other_PLK_PLK1_PLK1_ST	Q14676	MDC1	P53350	PLK1	S485	P491S	491	Missense	distal	6	no	10.999	10.855	EPSD	TCGA;ICGC;COSMIC	10.919	Loss
Other_PLK_PLK1_PLK1_ST	Q14676	MDC1	P53350	PLK1	S485	S485P	485	Missense	central	0	yes	10.999	0.000	EPSD	TCGA;ICGC	10.919	Loss
Other_PLK_PLK1_PLK1_ST	Q14676	MDC1	P53350	PLK1	S498	V499M	499	Missense	proximal	1	no	13.110	14.266	EPSD	TCGA;ICGC;COSMIC	10.919	Up-regulation
Other_PLK_PLK1_PLK1_ST	Q14676	MDC1	P53350	PLK1	S498	P491S	491	Missense	distal	-7	no	13.110	13.321	EPSD	TCGA;ICGC;COSMIC	10.919	Up-regulation
Other_PLK_PLK1_PLK1_ST	Q14676	MDC1	P53350	PLK1	S513	H509Y	509	Missense	distal	-4	no	10.946	10.524	EPSD	TCGA;ICGC;COSMIC	10.919	Loss
Other_PLK_PLK1_PLK1_ST	Q14676	MDC1	P53350	PLK1	T548	A555V	555	Missense	distal	7	no	11.319	11.342	EPSD	TCGA	10.919	Up-regulation
Other_PLK_PLK1_PLK1_ST	Q14676	MDC1	P53350	PLK1	T548	V543M	543	Missense	distal	-5	no	11.319	11.172	EPSD	TCGA;ICGC;COSMIC	10.919	Down-regulation
Other_PLK_PLK1_PLK1_ST	Q14676	MDC1	P53350	PLK1	S763	T770M	770	Missense	distal	7	no	11.461	11.544	EPSD	TCGA;ICGC;COSMIC	10.919	Up-regulation
Other_PLK_PLK1_PLK1_ST	Q14676	MDC1	P53350	PLK1	S763	E761K	761	Missense	proximal	-2	no	11.461	8.583	EPSD	TCGA;ICGC;COSMIC	10.919	Loss
Other_PLK_PLK1_PLK1_ST	Q14676	MDC1	P53350	PLK1	S763	E761D	761	Missense	proximal	-2	no	11.461	11.854	EPSD	TCGA;ICGC	10.919	Up-regulation
Other_PLK_PLK1_PLK1_ST	Q14676	MDC1	P53350	PLK1	S1195	G1189V	1189	Missense	distal	-6	no	11.095	11.367	EPSD	TCGA;COSMIC	10.919	Up-regulation
Other_PLK_PLK1_PLK1_ST	Q14676	MDC1	P53350	PLK1	S1195	S1194C	1194	Missense	proximal	-1	no	11.095	9.235	EPSD	TCGA;ICGC;COSMIC	10.919	Loss
Other_PLK_PLK1_PLK1_ST	Q14676	MDC1	P53350	PLK1	S1236	K1232N	1232	Missense	distal	-4	no	11.470	11.728	EPSD	TCGA;COSMIC	10.919	Up-regulation
Other_PLK_PLK1_PLK1_ST	Q14676	MDC1	P53350	PLK1	S1236	G1230E	1230	Missense	distal	-6	no	11.470	12.135	EPSD	TCGA	10.919	Up-regulation
Other_PLK_PLK1_PLK1_ST	Q14676	MDC1	P53350	PLK1	S1236	R1231I	1231	Missense	distal	-5	no	11.470	11.154	EPSD	TCGA;COSMIC	10.919	Down-regulation
Other_PLK_PLK1_PLK1_ST	Q14676	MDC1	P53350	PLK1	T1265	E1263Q	1263	Missense	proximal	-2	no	10.965	8.306	EPSD	TCGA;COSMIC	10.919	Loss
Other_PLK_PLK1_PLK1_ST	Q14676	MDC1	P53350	PLK1	T1265	Q1267E	1267	Missense	proximal	2	no	10.965	10.776	EPSD	TCGA;COSMIC	10.919	Loss
Other_PLK_PLK1_PLK1_ST	Q14676	MDC1	P53350	PLK1	S1317	R1313K	1313	Missense	distal	-4	no	11.780	11.953	EPSD	TCGA;COSMIC	10.919	Up-regulation
Other_PLK_PLK1_PLK1_ST	Q14676	MDC1	P53350	PLK1	S1317	T1321I	1321	Missense	distal	4	no	11.780	10.781	EPSD	TCGA;COSMIC	10.919	Loss
Other_PLK_PLK1_PLK1_ST	Q14676	MDC1	P53350	PLK1	S1318	R1313K	1313	Missense	distal	-5	no	12.733	12.195	EPSD	TCGA;COSMIC	10.919	Down-regulation
Other_PLK_PLK1_PLK1_ST	Q14676	MDC1	P53350	PLK1	S1318	T1321I	1321	Missense	distal	3	no	12.733	12.900	EPSD	TCGA;COSMIC	10.919	Up-regulation
Other_PLK_PLK1_PLK1_ST	Q14676	MDC1	P53350	PLK1	T1324	T1328I	1328	Missense	distal	4	no	11.558	10.559	EPSD	TCGA;COSMIC	10.919	Loss
Other_PLK_PLK1_PLK1_ST	Q14676	MDC1	P53350	PLK1	T1324	T1321I	1321	Missense	distal	-3	no	11.558	11.581	EPSD	TCGA;COSMIC	10.919	Up-regulation
Other_PLK_PLK1_PLK1_ST	Q14676	MDC1	P53350	PLK1	S1335	T1328I	1328	Missense	distal	-7	no	12.729	12.276	EPSD	TCGA;COSMIC	10.919	Down-regulation
Other_PLK_PLK1_PLK1_ST	Q14676	MDC1	P53350	PLK1	T1366	P1371S	1371	Missense	distal	5	no	11.738	11.351	EPSD	TCGA;COSMIC	10.919	Down-regulation
Other_PLK_PLK1_PLK1_ST	Q14676	MDC1	P53350	PLK1	T1366	P1368S	1368	Missense	proximal	2	no	11.738	13.215	EPSD	TCGA;COSMIC	10.919	Up-regulation
Other_PLK_PLK1_PLK1_ST	Q14676	MDC1	P53350	PLK1	S1417	P1416L	1416	Missense	proximal	-1	no	12.617	13.331	EPSD	TCGA;COSMIC	10.919	Up-regulation
Other_PLK_PLK1_PLK1_ST	Q14676	MDC1	P53350	PLK1	T1437	G1435D	1435	Missense	proximal	-2	no	8.018	11.339	EPSD	TCGA;COSMIC	10.919	Gain
Other_PLK_PLK1_PLK1_ST	Q14676	MDC1	P53350	PLK1	S1441	S1440F	1440	Missense	proximal	-1	no	10.987	10.448	EPSD	TCGA;COSMIC	10.919	Loss
Other_PLK_PLK1_PLK1_ST	Q14676	MDC1	P53350	PLK1	S1441	G1435D	1435	Missense	distal	-6	no	10.987	11.450	EPSD	TCGA;COSMIC	10.919	Up-regulation
Other_PLK_PLK1_PLK1_ST	Q14676	MDC1	P53350	PLK1	T1447	T1451A	1451	Missense	distal	4	no	11.042	11.036	EPSD	TCGA;COSMIC	10.919	Down-regulation
Other_PLK_PLK1_PLK1_ST	Q14676	MDC1	P53350	PLK1	T1447	S1440F	1440	Missense	distal	-7	no	11.042	10.585	EPSD	TCGA;COSMIC	10.919	Loss
Other_PLK_PLK1_PLK1_ST	Q14676	MDC1	P53350	PLK1	T1447	P1453L	1453	Missense	distal	6	no	11.042	10.938	EPSD	TCGA;COSMIC	10.919	Down-regulation
Other_PLK_PLK1_PLK1_ST	Q14676	MDC1	P53350	PLK1	S1458	P1453L	1453	Missense	distal	-5	no	10.656	11.058	EPSD	TCGA;COSMIC	10.919	Gain
Other_PLK_PLK1_PLK1_ST	Q14676	MDC1	P53350	PLK1	S1458	T1459I	1459	Missense	proximal	1	no	10.656	11.823	EPSD	TCGA;COSMIC	10.919	Gain
Other_PLK_PLK1_PLK1_ST	Q14676	MDC1	P53350	PLK1	S1481	R1480I	1480	Missense	proximal	-1	no	11.337	12.290	EPSD	TCGA	10.919	Up-regulation
Other_PLK_PLK1_PLK1_ST	Q14676	MDC1	P53350	PLK1	S1481	R1480K	1480	Missense	proximal	-1	no	11.337	11.698	EPSD	TCGA;COSMIC	10.919	Up-regulation
Other_PLK_PLK1_PLK1_ST	Q14676	MDC1	P53350	PLK1	S1499	D1503H	1503	Missense	distal	4	no	11.161	10.637	EPSD	TCGA;COSMIC	10.919	Loss
Other_PLK_PLK1_PLK1_ST	Q14676	MDC1	P53350	PLK1	S1522	R1518K	1518	Missense	distal	-4	no	11.593	11.766	EPSD	TCGA;COSMIC	10.919	Up-regulation
Other_PLK_PLK1_PLK1_ST	Q14676	MDC1	P53350	PLK1	S1522	R1521Q	1521	Missense	proximal	-1	no	11.593	12.197	EPSD	TCGA;COSMIC	10.919	Up-regulation
Other_PLK_PLK1_PLK1_ST	Q14676	MDC1	P53350	PLK1	S1522	R1518I	1518	Missense	distal	-4	no	11.593	12.193	EPSD	TCGA	10.919	Up-regulation
Other_PLK_PLK1_PLK1_ST	Q14676	MDC1	P53350	PLK1	S1523	R1518K	1518	Missense	distal	-5	no	11.802	11.264	EPSD	TCGA;COSMIC	10.919	Down-regulation
Other_PLK_PLK1_PLK1_ST	Q14676	MDC1	P53350	PLK1	S1523	R1521Q	1521	Missense	proximal	-2	no	11.802	11.627	EPSD	TCGA;COSMIC	10.919	Down-regulation
Other_PLK_PLK1_PLK1_ST	Q14676	MDC1	P53350	PLK1	S1523	R1518I	1518	Missense	distal	-5	no	11.802	11.486	EPSD	TCGA	10.919	Down-regulation
Other_PLK_PLK1_PLK1_ST	Q14676	MDC1	P53350	PLK1	S1540	A1533T	1533	Missense	distal	-7	no	10.688	11.033	EPSD	TCGA;COSMIC	10.919	Gain
Other_PLK_PLK1_PLK1_ST	Q14676	MDC1	P53350	PLK1	T1552	S1553F	1553	Missense	proximal	1	no	8.735	11.783	EPSD	TCGA;COSMIC	10.919	Gain
Other_PLK_PLK1_PLK1_ST	Q14676	MDC1	P53350	PLK1	S1563	R1562K	1562	Missense	proximal	-1	no	10.963	11.325	EPSD	TCGA;COSMIC	10.919	Up-regulation
Other_PLK_PLK1_PLK1_ST	Q14676	MDC1	P53350	PLK1	S1563	K1566N	1566	Missense	distal	3	no	10.963	11.035	EPSD	TCGA	10.919	Up-regulation
Other_PLK_PLK1_PLK1_ST	Q14676	MDC1	P53350	PLK1	S1564	R1562K	1562	Missense	proximal	-2	no	11.022	10.629	EPSD	TCGA;COSMIC	10.919	Loss
Other_PLK_PLK1_PLK1_ST	Q14676	MDC1	P53350	PLK1	S1564	K1566N	1566	Missense	proximal	2	no	11.022	11.996	EPSD	TCGA	10.919	Up-regulation
Other_PLK_PLK1_PLK1_ST	Q14676	MDC1	P53350	PLK1	S1605	V1606F	1606	Missense	proximal	1	no	10.164	11.644	EPSD	TCGA	10.919	Gain
Other_PLK_PLK1_PLK1_ST	Q14676	MDC1	P53350	PLK1	S1669	V1670I	1670	Missense	proximal	1	no	13.172	13.363	EPSD	TCGA;COSMIC	10.919	Up-regulation
Other_PLK_PLK1_PLK1_ST	Q14676	MDC1	P53350	PLK1	S1814	K1812N	1812	Missense	proximal	-2	no	8.957	10.986	EPSD	TCGA;ICGC;COSMIC	10.919	Gain
Other_PLK_PLK1_PLK1_ST	Q14676	MDC1	P53350	PLK1	S1833	P1827S	1827	Missense	distal	-6	no	10.296	10.919	EPSD	TCGA;COSMIC	10.919	Gain
Other_PLK_PLK1_PLK1_ST	Q14676	MDC1	P53350	PLK1	S1915	G1913V	1913	Missense	proximal	-2	no	11.282	11.992	EPSD	TCGA;ICGC;COSMIC	10.919	Up-regulation
Other_PLK_PLK1_PLK1_ST	Q14676	MDC1	P53350	PLK1	S1924	S1924F	1924	Missense	central	0	yes	12.058	0.000	EPSD	TCGA;COSMIC	10.919	Loss
Other_PLK_PLK1_PLK1_ST	O00139	KIF2A	P53350	PLK1	S135	D138Y	138	Missense	distal	3	no	11.374	10.948	EPSD	TCGA	10.919	Down-regulation
Other_PLK_PLK1_PLK1_ST	O00139	KIF2A	P53350	PLK1	S135	Q132H	132	Missense	distal	-3	no	11.374	11.377	EPSD	TCGA	10.919	Up-regulation
Other_PLK_PLK1_PLK1_ST	O00139	KIF2A	P53350	PLK1	S516	S516C	516	Missense	central	0	yes	14.156	0.000	EPSD	TCGA	10.919	Loss
Other_PLK_PLK1_PLK1_ST	O00139	KIF2A	P53350	PLK1	S516	R523H	523	Missense	distal	7	no	14.156	14.126	EPSD	TCGA;COSMIC	10.919	Down-regulation
Other_PLK_PLK1_PLK1_ST	O00139	KIF2A	P53350	PLK1	T554	N548Y	548	Missense	distal	-6	no	12.954	12.297	PhosphoSitePlus	TCGA;COSMIC	10.919	Down-regulation
Other_PLK_PLK1_PLK1_ST	O00139	KIF2A	P53350	PLK1	T554	P557S	557	Missense	distal	3	no	12.954	12.932	PhosphoSitePlus	TCGA	10.919	Down-regulation
Other_PLK_PLK1_PLK1_ST	O00139	KIF2A	P53350	PLK1	T558	P557S	557	Missense	proximal	-1	no	10.333	11.507	EPSD	TCGA	10.919	Gain
Other_PLK_PLK1_PLK1_ST	P30260	CDC27	P53350	PLK1	T200	T203M	203	Missense	distal	3	no	10.943	10.790	EPSD	TCGA;ICGC;COSMIC	10.919	Loss
Other_PLK_PLK1_PLK1_ST	P30260	CDC27	P53350	PLK1	T205	T203M	203	Missense	proximal	-2	no	12.506	12.589	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	10.919	Up-regulation
Other_PLK_PLK1_PLK1_ST	P30260	CDC27	P53350	PLK1	S241	P246S	246	Missense	distal	5	no	11.820	11.433	EPSD	TCGA;ICGC;COSMIC	10.919	Down-regulation
Other_PLK_PLK1_PLK1_ST	P30260	CDC27	P53350	PLK1	T244	P246S	246	Missense	proximal	2	no	9.479	10.956	EPSD	TCGA;ICGC;COSMIC	10.919	Gain
Other_PLK_PLK1_PLK1_ST	Q6PGQ7	BORA	P53350	PLK1	S233	S229L	229	Missense	distal	-4	no	13.521	13.327	EPSD	TCGA;ICGC	10.919	Down-regulation
Other_PLK_PLK1_PLK1_ST	Q6PGQ7	BORA	P53350	PLK1	S233	D231Y	231	Missense	proximal	-2	no	13.521	11.979	EPSD	TCGA;ICGC	10.919	Down-regulation
Other_PLK_PLK1_PLK1_ST	Q6PGQ7	BORA	P53350	PLK1	S252	S257T	257	Missense	distal	5	no	11.263	10.658	EPSD	TCGA;ICGC	10.919	Loss
Other_PLK_PLK1_PLK1_ST	Q6PGQ7	BORA	P53350	PLK1	S252	S246L	246	Missense	distal	-6	no	11.263	10.929	EPSD	TCGA;ICGC	10.919	Down-regulation
Other_PLK_PLK1_PLK1_ST	Q6PGQ7	BORA	P53350	PLK1	S270	I272V	272	Missense	proximal	2	no	11.410	11.193	EPSD	TCGA;ICGC	10.919	Down-regulation
Other_PLK_PLK1_PLK1_ST	Q6PGQ7	BORA	P53350	PLK1	T296	K294T	294	Missense	proximal	-2	no	11.293	11.373	EPSD	TCGA;ICGC	10.919	Up-regulation
Other_PLK_PLK1_PLK1_ST	Q6PGQ7	BORA	P53350	PLK1	S374	T371K	371	Missense	distal	-3	no	11.671	11.666	EPSD	TCGA;ICGC	10.919	Down-regulation
Other_PLK_PLK1_PLK1_ST	Q6PGQ7	BORA	P53350	PLK1	S374	A377T	377	Missense	distal	3	no	11.671	11.710	EPSD	TCGA;ICGC	10.919	Up-regulation
Other_PLK_PLK1_PLK1_ST	Q6PGQ7	BORA	P53350	PLK1	S374	D379N	379	Missense	distal	5	no	11.671	10.918	EPSD	TCGA;ICGC	10.919	Loss
Other_PLK_PLK1_PLK1_ST	Q6PGQ7	BORA	P53350	PLK1	T445	D443H	443	Missense	proximal	-2	no	12.061	8.874	EPSD	TCGA;ICGC	10.919	Loss
Other_PLK_PLK1_PLK1_ST	Q6PGQ7	BORA	P53350	PLK1	T445	E440Q	440	Missense	distal	-5	no	12.061	12.103	EPSD	TCGA;ICGC	10.919	Up-regulation
Other_PLK_PLK1_PLK1_ST	Q6PGQ7	BORA	P53350	PLK1	T446	D443H	443	Missense	distal	-3	no	11.510	11.380	EPSD	TCGA;ICGC	10.919	Down-regulation
Other_PLK_PLK1_PLK1_ST	Q6PGQ7	BORA	P53350	PLK1	T446	E440Q	440	Missense	distal	-6	no	11.510	11.391	EPSD	TCGA;ICGC	10.919	Down-regulation
Other_PLK_PLK1_PLK1_ST	Q96CV9	OPTN	P53350	PLK1	T34	L32V	32	Missense	proximal	-2	no	10.816	11.804	EPSD	TCGA;ICGC;COSMIC	10.919	Gain
Other_PLK_PLK1_PLK1_ST	Q96CV9	OPTN	P53350	PLK1	S171	N169S	169	Missense	proximal	-2	no	13.110	11.701	EPSD	TCGA	10.919	Down-regulation
Other_PLK_PLK1_PLK1_ST	Q96CV9	OPTN	P53350	PLK1	S171	D176Y	176	Missense	distal	5	no	13.110	12.804	EPSD	TCGA;ICGC;COSMIC	10.919	Down-regulation
Other_PLK_PLK1_PLK1_ST	Q96CV9	OPTN	P53350	PLK1	S171	E175Q	175	Missense	distal	4	no	13.110	12.707	EPSD	TCGA;ICGC;COSMIC	10.919	Down-regulation
Other_PLK_PLK1_PLK1_ST	Q96CV9	OPTN	P53350	PLK1	S171	F178V	178	Missense	distal	7	no	13.110	13.089	EPSD	TCGA;ICGC;COSMIC	10.919	Down-regulation
Other_PLK_PLK1_PLK1_ST	Q96CV9	OPTN	P53350	PLK1	S177	A184S	184	Missense	distal	7	no	17.537	17.512	PhosphoSitePlus	TCGA;ICGC;COSMIC	10.919	Down-regulation
Other_PLK_PLK1_PLK1_ST	Q96CV9	OPTN	P53350	PLK1	S177	D176Y	176	Missense	proximal	-1	no	17.537	17.080	PhosphoSitePlus	TCGA;ICGC;COSMIC	10.919	Down-regulation
Other_PLK_PLK1_PLK1_ST	Q96CV9	OPTN	P53350	PLK1	S177	E175Q	175	Missense	proximal	-2	no	17.537	14.878	PhosphoSitePlus	TCGA;ICGC;COSMIC	10.919	Down-regulation
Other_PLK_PLK1_PLK1_ST	Q96CV9	OPTN	P53350	PLK1	S177	F178V	178	Missense	proximal	1	no	17.537	16.057	PhosphoSitePlus	TCGA;ICGC;COSMIC	10.919	Down-regulation
Other_PLK_PLK1_PLK1_ST	Q96CV9	OPTN	P53350	PLK1	S177	A184D	184	Missense	distal	7	no	17.537	17.485	PhosphoSitePlus	TCGA;ICGC	10.919	Down-regulation
Other_PLK_PLK1_PLK1_ST	Q96CV9	OPTN	P53350	PLK1	S234	T232I	232	Missense	proximal	-2	no	11.744	11.719	EPSD	TCGA;ICGC;COSMIC	10.919	Down-regulation
Other_PLK_PLK1_PLK1_ST	Q96CV9	OPTN	P53350	PLK1	S234	L237P	237	Missense	distal	3	no	11.744	11.912	EPSD	TCGA;ICGC;COSMIC	10.919	Up-regulation
Other_PLK_PLK1_PLK1_ST	Q96CV9	OPTN	P53350	PLK1	S272	E279Q	279	Missense	distal	7	no	11.062	11.115	EPSD	TCGA;ICGC;COSMIC	10.919	Up-regulation
Other_PLK_PLK1_PLK1_ST	Q96CV9	OPTN	P53350	PLK1	S272	R271C	271	Missense	proximal	-1	no	11.062	10.138	EPSD	TCGA;ICGC;COSMIC	10.919	Loss
Other_PLK_PLK1_PLK1_ST	Q96CV9	OPTN	P53350	PLK1	S272	E273Q	273	Missense	proximal	1	no	11.062	11.185	EPSD	TCGA;ICGC;COSMIC	10.919	Up-regulation
Other_PLK_PLK1_PLK1_ST	Q96CV9	OPTN	P53350	PLK1	S513	G509R	509	Missense	distal	-4	no	11.791	11.878	EPSD	TCGA;ICGC;COSMIC	10.919	Up-regulation
Other_PLK_PLK1_PLK1_ST	Q9HAW4	CLSPN	P53350	PLK1	S30	D25E	25	Missense	distal	-5	no	12.409	12.068	PhosphoSitePlus	TCGA;ICGC;COSMIC	10.919	Down-regulation
Other_PLK_PLK1_PLK1_ST	Q9HAW4	CLSPN	P53350	PLK1	S30	P27L	27	Missense	distal	-3	no	12.409	13.601	PhosphoSitePlus	TCGA;ICGC;COSMIC	10.919	Up-regulation
Other_PLK_PLK1_PLK1_ST	Q9HAW4	CLSPN	P53350	PLK1	S30	A24T	24	Missense	distal	-6	no	12.409	12.342	PhosphoSitePlus	TCGA;ICGC;COSMIC	10.919	Down-regulation
Other_PLK_PLK1_PLK1_ST	Q9HAW4	CLSPN	P53350	PLK1	S65	S67F	67	Missense	proximal	2	no	11.089	10.538	EPSD	TCGA;ICGC;COSMIC	10.919	Loss
Other_PLK_PLK1_PLK1_ST	Q9HAW4	CLSPN	P53350	PLK1	S65	Q63E	63	Missense	proximal	-2	no	11.089	13.748	EPSD	TCGA;ICGC;COSMIC	10.919	Up-regulation
Other_PLK_PLK1_PLK1_ST	Q9HAW4	CLSPN	P53350	PLK1	T72	S67F	67	Missense	distal	-5	no	11.782	11.520	EPSD	TCGA;ICGC;COSMIC	10.919	Down-regulation
Other_PLK_PLK1_PLK1_ST	Q9HAW4	CLSPN	P53350	PLK1	T72	P76S	76	Missense	distal	4	no	11.782	12.103	EPSD	TCGA;ICGC;COSMIC	10.919	Up-regulation
Other_PLK_PLK1_PLK1_ST	Q9HAW4	CLSPN	P53350	PLK1	T79	E85K	85	Missense	distal	6	no	11.539	11.470	EPSD	TCGA;ICGC;COSMIC;GDSC	10.919	Down-regulation
Other_PLK_PLK1_PLK1_ST	Q9HAW4	CLSPN	P53350	PLK1	T79	P76S	76	Missense	distal	-3	no	11.539	11.957	EPSD	TCGA;ICGC;COSMIC	10.919	Up-regulation
Other_PLK_PLK1_PLK1_ST	Q9HAW4	CLSPN	P53350	PLK1	S83	E85K	85	Missense	proximal	2	no	12.550	12.381	EPSD	TCGA;ICGC;COSMIC;GDSC	10.919	Down-regulation
Other_PLK_PLK1_PLK1_ST	Q9HAW4	CLSPN	P53350	PLK1	S83	N88Y	88	Missense	distal	5	no	12.550	12.997	EPSD	TCGA;ICGC;COSMIC	10.919	Up-regulation
Other_PLK_PLK1_PLK1_ST	Q9HAW4	CLSPN	P53350	PLK1	S83	P76S	76	Missense	distal	-7	no	12.550	12.761	EPSD	TCGA;ICGC;COSMIC	10.919	Up-regulation
Other_PLK_PLK1_PLK1_ST	Q9HAW4	CLSPN	P53350	PLK1	S83	E90D	90	Missense	distal	7	no	12.550	12.546	EPSD	TCGA;ICGC;COSMIC	10.919	Down-regulation
Other_PLK_PLK1_PLK1_ST	Q9HAW4	CLSPN	P53350	PLK1	T106	R102M	102	Missense	distal	-4	no	11.758	12.049	EPSD	TCGA;ICGC	10.919	Up-regulation
Other_PLK_PLK1_PLK1_ST	Q9HAW4	CLSPN	P53350	PLK1	T106	R102T	102	Missense	distal	-4	no	11.758	11.962	EPSD	TCGA;ICGC;COSMIC	10.919	Up-regulation
Other_PLK_PLK1_PLK1_ST	Q9HAW4	CLSPN	P53350	PLK1	S113	L119S	119	Missense	distal	6	no	13.398	13.359	EPSD	TCGA;ICGC;COSMIC	10.919	Down-regulation
Other_PLK_PLK1_PLK1_ST	Q9HAW4	CLSPN	P53350	PLK1	S232	I236T	236	Missense	distal	4	no	11.930	12.929	EPSD	TCGA;ICGC;COSMIC	10.919	Up-regulation
Other_PLK_PLK1_PLK1_ST	Q9HAW4	CLSPN	P53350	PLK1	S232	A238T	238	Missense	distal	6	no	11.930	11.923	EPSD	TCGA;ICGC;COSMIC	10.919	Down-regulation
Other_PLK_PLK1_PLK1_ST	Q9HAW4	CLSPN	P53350	PLK1	S260	S253F	253	Missense	distal	-7	no	12.455	11.998	EPSD	TCGA;ICGC;COSMIC	10.919	Down-regulation
Other_PLK_PLK1_PLK1_ST	Q9HAW4	CLSPN	P53350	PLK1	S260	G257V	257	Missense	distal	-3	no	12.455	11.806	EPSD	TCGA;ICGC;COSMIC	10.919	Down-regulation
Other_PLK_PLK1_PLK1_ST	Q9HAW4	CLSPN	P53350	PLK1	T353	M356I	356	Missense	distal	3	no	10.686	11.005	EPSD	TCGA;ICGC;COSMIC	10.919	Gain
Other_PLK_PLK1_PLK1_ST	Q9HAW4	CLSPN	P53350	PLK1	T387	S384L	384	Missense	distal	-3	no	10.497	11.272	EPSD	TCGA;ICGC;COSMIC	10.919	Gain
Other_PLK_PLK1_PLK1_ST	Q9HAW4	CLSPN	P53350	PLK1	S516	E523K	523	Missense	distal	7	no	14.014	14.087	EPSD	TCGA;ICGC;COSMIC	10.919	Up-regulation
Other_PLK_PLK1_PLK1_ST	Q9HAW4	CLSPN	P53350	PLK1	S516	S516F	516	Missense	central	0	yes	14.014	0.000	EPSD	TCGA;ICGC;COSMIC	10.919	Loss
Other_PLK_PLK1_PLK1_ST	Q9HAW4	CLSPN	P53350	PLK1	S516	R509W	509	Missense	distal	-7	no	14.014	14.600	EPSD	TCGA;ICGC;COSMIC	10.919	Up-regulation
Other_PLK_PLK1_PLK1_ST	Q9HAW4	CLSPN	P53350	PLK1	S642	E637D	637	Missense	distal	-5	no	10.685	11.027	EPSD	TCGA	10.919	Gain
Other_PLK_PLK1_PLK1_ST	Q9HAW4	CLSPN	P53350	PLK1	S718	S723Y	723	Missense	distal	5	no	11.339	11.181	EPSD	TCGA;COSMIC	10.919	Down-regulation
Other_PLK_PLK1_PLK1_ST	Q9HAW4	CLSPN	P53350	PLK1	T724	S723Y	723	Missense	proximal	-1	no	10.943	11.278	EPSD	TCGA;COSMIC	10.919	Up-regulation
Other_PLK_PLK1_PLK1_ST	Q9HAW4	CLSPN	P53350	PLK1	S798	G796E	796	Missense	proximal	-2	no	9.169	12.097	EPSD	TCGA;COSMIC	10.919	Gain
Other_PLK_PLK1_PLK1_ST	Q9HAW4	CLSPN	P53350	PLK1	S839	A845T	845	Missense	distal	6	no	12.769	12.762	EPSD	TCGA;COSMIC	10.919	Down-regulation
Other_PLK_PLK1_PLK1_ST	Q9HAW4	CLSPN	P53350	PLK1	S839	S839F	839	Missense	central	0	yes	12.769	0.000	EPSD	TCGA;COSMIC	10.919	Loss
Other_PLK_PLK1_PLK1_ST	Q9HAW4	CLSPN	P53350	PLK1	S954	S954F	954	Missense	central	0	yes	11.723	0.000	EPSD	TCGA;ICGC;COSMIC	10.919	Loss
Other_PLK_PLK1_PLK1_ST	Q9HAW4	CLSPN	P53350	PLK1	S969	E967K	967	Missense	proximal	-2	no	13.432	10.555	EPSD	TCGA	10.919	Loss
Other_PLK_PLK1_PLK1_ST	Q9HAW4	CLSPN	P53350	PLK1	S1147	D1145G	1145	Missense	proximal	-2	no	11.081	7.759	EPSD	TCGA;COSMIC	10.919	Loss
Other_PLK_PLK1_PLK1_ST	Q9HAW4	CLSPN	P53350	PLK1	S1147	D1144Y	1144	Missense	distal	-3	no	11.081	11.260	EPSD	TCGA	10.919	Up-regulation
Other_PLK_PLK1_PLK1_ST	Q9HAW4	CLSPN	P53350	PLK1	S1204	I1208M	1208	Missense	distal	4	no	10.879	11.122	EPSD	TCGA	10.919	Gain
Other_PLK_PLK1_PLK1_ST	Q9HAW4	CLSPN	P53350	PLK1	S1302	A1295T	1295	Missense	distal	-7	no	11.298	11.643	EPSD	TCGA;ICGC;COSMIC	10.919	Up-regulation
Other_PLK_PLK1_PLK1_ST	Q9HAW4	CLSPN	P53350	PLK1	S1310	S1310C	1310	Missense	central	0	yes	11.573	0.000	EPSD	TCGA;COSMIC	10.919	Loss
Other_PLK_PLK1_PLK1_ST	Q9HAW4	CLSPN	P53350	PLK1	S1310	S1314Y	1314	Missense	distal	4	no	11.573	11.330	EPSD	TCGA;COSMIC	10.919	Down-regulation
Other_PLK_PLK1_PLK1_ST	Q9HAW4	CLSPN	P53350	PLK1	S1316	S1310C	1310	Missense	distal	-6	no	10.945	9.742	EPSD	TCGA;COSMIC	10.919	Loss
Other_PLK_PLK1_PLK1_ST	Q9HAW4	CLSPN	P53350	PLK1	S1316	S1314Y	1314	Missense	proximal	-2	no	10.945	12.055	EPSD	TCGA;COSMIC	10.919	Up-regulation
Other_PLK_PLK1_PLK1_ST	Q9HAW4	CLSPN	P53350	PLK1	S1325	R1331Q	1331	Missense	distal	6	no	13.277	13.565	EPSD	TCGA;ICGC;COSMIC	10.919	Up-regulation
Other_PLK_PLK1_PLK1_ST	Q9HAW4	CLSPN	P53350	PLK1	S1325	T1330A	1330	Missense	distal	5	no	13.277	14.449	EPSD	TCGA;ICGC;COSMIC	10.919	Up-regulation
Other_PLK_PLK1_PLK1_ST	Q9HAW4	CLSPN	P53350	PLK1	S1325	S1327L	1327	Missense	proximal	2	no	13.277	13.349	EPSD	TCGA;COSMIC	10.919	Up-regulation
Other_PLK_PLK1_PLK1_ST	Q9HAW4	CLSPN	P53350	PLK1	T1326	R1331Q	1331	Missense	distal	5	no	12.128	11.333	EPSD	TCGA;ICGC;COSMIC	10.919	Down-regulation
Other_PLK_PLK1_PLK1_ST	Q9HAW4	CLSPN	P53350	PLK1	T1326	T1330A	1330	Missense	distal	4	no	12.128	12.122	EPSD	TCGA;ICGC;COSMIC	10.919	Down-regulation
Other_PLK_PLK1_PLK1_ST	Q9HAW4	CLSPN	P53350	PLK1	T1326	S1327L	1327	Missense	proximal	1	no	12.128	14.096	EPSD	TCGA;COSMIC	10.919	Up-regulation
Other_PLK_PLK1_PLK1_ST	Q9HAW4	CLSPN	P53350	PLK1	S1332	F1334L	1334	Missense	proximal	2	no	10.399	11.022	EPSD	TCGA;ICGC;COSMIC	10.919	Gain
Other_PLK_PLK1_PLK1_ST	Q9HAW4	CLSPN	P53350	PLK1	S1332	R1331Q	1331	Missense	proximal	-1	no	10.399	11.003	EPSD	TCGA;ICGC;COSMIC	10.919	Gain
Other_PLK_PLK1_PLK1_ST	Q9HAW4	CLSPN	P53350	PLK1	S1332	T1330A	1330	Missense	proximal	-2	no	10.399	11.018	EPSD	TCGA;ICGC;COSMIC	10.919	Gain
Other_PLK_PLK1_PLK1_ST	Q9HAW4	CLSPN	P53350	PLK1	S1332	S1327L	1327	Missense	distal	-5	no	10.399	11.063	EPSD	TCGA;COSMIC	10.919	Gain
Other_PLK_PLK1_PLK1_ST	Q13526	PIN1	P53350	PLK1	S65	S71L	71	Missense	distal	6	no	11.635	11.675	PhosphoSitePlus	TCGA;ICGC;COSMIC	10.919	Up-regulation
Other_PLK_PLK1_PLK1_ST	Q13526	PIN1	P53350	PLK1	S138	T143M	143	Missense	distal	5	no	12.530	13.232	EPSD	TCGA	10.919	Up-regulation
Other_PLK_PLK1_PLK1_ST	Q13526	PIN1	P53350	PLK1	S138	F139S	139	Missense	proximal	1	no	12.530	9.482	EPSD	TCGA;ICGC;COSMIC	10.919	Loss
Other_PLK_PLK1_PLK1_ST	Q13526	PIN1	P53350	PLK1	S138	E145K	145	Missense	distal	7	no	12.530	12.603	EPSD	TCGA;ICGC;COSMIC	10.919	Up-regulation
Other_PLK_PLK1_PLK1_ST	Q13526	PIN1	P53350	PLK1	S138	R142L	142	Missense	distal	4	no	12.530	12.863	EPSD	TCGA;ICGC;COSMIC	10.919	Up-regulation
Other_PLK_PLK1_PLK1_ST	Q13526	PIN1	P53350	PLK1	S138	A137T	137	Missense	proximal	-1	no	12.530	12.250	EPSD	TCGA;ICGC;GDSC;CCLE	10.919	Down-regulation
Other_PLK_PLK1_PLK1_ST	Q13526	PIN1	P53350	PLK1	S147	T143M	143	Missense	distal	-4	no	11.576	11.662	EPSD	TCGA	10.919	Up-regulation
Other_PLK_PLK1_PLK1_ST	Q13526	PIN1	P53350	PLK1	S147	E145K	145	Missense	proximal	-2	no	11.576	8.699	EPSD	TCGA;ICGC;COSMIC	10.919	Loss
Other_PLK_PLK1_PLK1_ST	Q13526	PIN1	P53350	PLK1	S147	S154F	154	Missense	distal	7	no	11.576	11.645	EPSD	TCGA;ICGC;COSMIC	10.919	Up-regulation
Other_PLK_PLK1_PLK1_ST	Q13526	PIN1	P53350	PLK1	S147	G148R	148	Missense	proximal	1	no	11.576	9.475	EPSD	TCGA;ICGC;COSMIC	10.919	Loss
Other_PLK_PLK1_PLK1_ST	Q13526	PIN1	P53350	PLK1	S147	R142L	142	Missense	distal	-5	no	11.576	11.556	EPSD	TCGA;ICGC;COSMIC	10.919	Down-regulation
Other_PLK_PLK1_PLK1_ST	Q14674	ESPL1	P53350	PLK1	S325	S319L	319	Missense	distal	-6	no	13.012	12.677	EPSD	TCGA;ICGC;COSMIC	10.919	Down-regulation
Other_PLK_PLK1_PLK1_ST	Q14674	ESPL1	P53350	PLK1	S810	R805I	805	Missense	distal	-5	no	14.086	13.771	EPSD	TCGA;ICGC;COSMIC	10.919	Down-regulation
Other_PLK_PLK1_PLK1_ST	Q14674	ESPL1	P53350	PLK1	S810	S810L	810	Missense	central	0	yes	14.086	0.000	EPSD	TCGA;ICGC;COSMIC	10.919	Loss
Other_PLK_PLK1_PLK1_ST	Q14674	ESPL1	P53350	PLK1	T1111	K1114M	1114	Missense	distal	3	no	11.985	11.722	EPSD	TCGA;ICGC;COSMIC	10.919	Down-regulation
Other_PLK_PLK1_PLK1_ST	Q14674	ESPL1	P53350	PLK1	S1399	D1403N	1403	Missense	distal	4	no	15.258	15.019	PhosphoSitePlus;EPSD	TCGA;ICGC;COSMIC	10.919	Down-regulation
Other_PLK_PLK1_PLK1_ST	Q14674	ESPL1	P53350	PLK1	T1519	E1525V	1525	Missense	distal	6	no	11.626	11.612	EPSD	TCGA;ICGC;COSMIC	10.919	Down-regulation
Other_PLK_PLK1_PLK1_ST	Q9UJX3	ANAPC7	P53350	PLK1	S64	N66S	66	Missense	proximal	2	no	10.971	10.757	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	10.919	Loss
Other_PLK_PLK1_PLK1_ST	Q9UJX3	ANAPC7	P53350	PLK1	T126	G121R	121	Missense	distal	-5	no	10.635	10.920	EPSD	TCGA;ICGC;COSMIC	10.919	Gain
Other_PLK_PLK1_PLK1_ST	Q9UJX3	ANAPC7	P53350	PLK1	S557	P558L	558	Missense	proximal	1	no	12.170	13.016	EPSD	TCGA;ICGC;COSMIC	10.919	Up-regulation
Other_PLK_PLK1_PLK1_ST	Q9UJX3	ANAPC7	P53350	PLK1	S557	E553K	553	Missense	distal	-4	no	12.170	11.787	EPSD	TCGA;ICGC;COSMIC	10.919	Down-regulation
Other_PLK_PLK1_PLK1_ST	P47736	RAP1GAP	P53350	PLK1	S606	S606F	606	Missense	central	0	yes	12.217	0.000	EPSD	TCGA;COSMIC	10.919	Loss
Other_PLK_PLK1_PLK1_ST	P47736	RAP1GAP	P53350	PLK1	T611	S606F	606	Missense	distal	-5	no	11.920	11.659	EPSD	TCGA;COSMIC	10.919	Down-regulation
Other_PLK_PLK1_PLK1_ST	Q15208	STK38	P53350	PLK1	T21	T26S	26	Missense	distal	5	no	10.333	10.938	EPSD	TCGA;ICGC;COSMIC	10.919	Gain
Other_PLK_PLK1_PLK1_ST	Q15208	STK38	P53350	PLK1	T26	E28D	28	Missense	proximal	2	no	10.528	11.119	EPSD	TCGA;ICGC;COSMIC	10.919	Gain
Other_PLK_PLK1_PLK1_ST	Q15208	STK38	P53350	PLK1	T183	E186K	186	Missense	distal	3	no	15.438	15.231	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC;CCLE	10.919	Down-regulation
Other_PLK_PLK1_PLK1_ST	Q15208	STK38	P53350	PLK1	T183	E188K	188	Missense	distal	5	no	15.438	15.449	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	10.919	Up-regulation
Other_PLK_PLK1_PLK1_ST	Q15208	STK38	P53350	PLK1	T183	D182H	182	Missense	proximal	-1	no	15.438	14.706	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	10.919	Down-regulation
Other_PLK_PLK1_PLK1_ST	Q15208	STK38	P53350	PLK1	S252	D256N	256	Missense	distal	4	no	12.466	12.228	EPSD	TCGA;ICGC;COSMIC	10.919	Down-regulation
Other_PLK_PLK1_PLK1_ST	Q15208	STK38	P53350	PLK1	S252	H251Y	251	Missense	proximal	-1	no	12.466	12.741	EPSD	TCGA;ICGC;COSMIC	10.919	Up-regulation
Other_PLK_PLK1_PLK1_ST	Q15208	STK38	P53350	PLK1	T258	D256N	256	Missense	proximal	-2	no	11.535	10.292	EPSD	TCGA;ICGC;COSMIC	10.919	Loss
Other_PLK_PLK1_PLK1_ST	Q15208	STK38	P53350	PLK1	T258	H251Y	251	Missense	distal	-7	no	11.535	11.040	EPSD	TCGA;ICGC;COSMIC	10.919	Down-regulation
Other_PLK_PLK1_PLK1_ST	Q15208	STK38	P53350	PLK1	T444	F448C	448	Missense	distal	4	no	10.690	10.977	EPSD	TCGA;ICGC	10.919	Gain
Other_PLK_PLK1_PLK1_ST	O75170	PPP6R2	P53350	PLK1	S822	A819G	819	Missense	distal	-3	no	11.006	11.256	EPSD	TCGA;ICGC;COSMIC	10.919	Up-regulation
Other_PLK_PLK1_PLK1_ST	O75170	PPP6R2	P53350	PLK1	S823	A819G	819	Missense	distal	-4	no	11.551	10.858	EPSD	TCGA;ICGC;COSMIC	10.919	Loss
Other_PLK_PLK1_PLK1_ST	O75170	PPP6R2	P53350	PLK1	S830	G833S	833	Missense	distal	3	no	13.332	13.329	EPSD	TCGA;ICGC;COSMIC	10.919	Down-regulation
Other_PLK_PLK1_PLK1_ST	O14920	IKBKB	P53350	PLK1	S393	E398D	398	Missense	distal	5	no	12.312	12.753	EPSD	TCGA;COSMIC	10.919	Up-regulation
Other_PLK_PLK1_PLK1_ST	O14920	IKBKB	P53350	PLK1	T399	E398D	398	Missense	proximal	-1	no	11.782	12.578	EPSD	TCGA;COSMIC	10.919	Up-regulation
Other_PLK_PLK1_PLK1_ST	O14920	IKBKB	P53350	PLK1	S402	E398D	398	Missense	distal	-4	no	11.315	11.130	EPSD	TCGA;COSMIC	10.919	Down-regulation
Other_PLK_PLK1_PLK1_ST	O14920	IKBKB	P53350	PLK1	S550	R554Q	554	Missense	distal	4	no	11.849	12.379	EPSD	TCGA;ICGC;COSMIC	10.919	Up-regulation
Other_PLK_PLK1_PLK1_ST	O14920	IKBKB	P53350	PLK1	S550	P551L	551	Missense	proximal	1	no	11.849	12.695	EPSD	TCGA;ICGC;COSMIC	10.919	Up-regulation
Other_PLK_PLK1_PLK1_ST	O14920	IKBKB	P53350	PLK1	S634	V633A	633	Missense	proximal	-1	no	10.504	10.993	EPSD	TCGA;ICGC	10.919	Gain
Other_PLK_PLK1_PLK1_ST	O14920	IKBKB	P53350	PLK1	S692	Q690E	690	Missense	proximal	-2	no	9.997	12.656	EPSD	TCGA;COSMIC	10.919	Gain
Other_PLK_PLK1_PLK1_ST	O14920	IKBKB	P53350	PLK1	S750	E748V	748	Missense	proximal	-2	no	13.980	11.762	EPSD;PhosphoSitePlus	TCGA	10.919	Down-regulation
Other_PLK_PLK1_PLK1_ST	O14920	IKBKB	P53350	PLK1	S750	E748K	748	Missense	proximal	-2	no	13.980	11.103	EPSD;PhosphoSitePlus	TCGA	10.919	Down-regulation
Other_PLK_PLK1_PLK1_ST	Q9NYZ3	GTSE1	P53350	PLK1	S168	P172S	172	Missense	distal	4	no	10.915	11.237	EPSD	TCGA;ICGC;COSMIC	10.919	Gain
Other_PLK_PLK1_PLK1_ST	Q9NYZ3	GTSE1	P53350	PLK1	S174	P172S	172	Missense	proximal	-2	no	10.932	11.516	EPSD	TCGA;ICGC;COSMIC	10.919	Up-regulation
Other_PLK_PLK1_PLK1_ST	Q9NYZ3	GTSE1	P53350	PLK1	S174	P172L	172	Missense	proximal	-2	no	10.932	10.568	EPSD	TCGA;ICGC;COSMIC	10.919	Loss
Other_PLK_PLK1_PLK1_ST	P11388	TOP2A	P53350	PLK1	T282	S285F	285	Missense	distal	3	no	12.520	12.580	EPSD	TCGA;ICGC;COSMIC	10.919	Up-regulation
Other_PLK_PLK1_PLK1_ST	P11388	TOP2A	P53350	PLK1	T382	S387R	387	Missense	distal	5	no	10.719	11.064	EPSD	TCGA	10.919	Gain
Other_PLK_PLK1_PLK1_ST	P11388	TOP2A	P53350	PLK1	T694	D697Y	697	Missense	distal	3	no	11.584	11.159	EPSD	TCGA;ICGC;COSMIC	10.919	Down-regulation
Other_PLK_PLK1_PLK1_ST	P11388	TOP2A	P53350	PLK1	T694	T689N	689	Missense	distal	-5	no	11.584	11.317	EPSD	TCGA;ICGC;COSMIC	10.919	Down-regulation
Other_PLK_PLK1_PLK1_ST	P11388	TOP2A	P53350	PLK1	T808	S812F	812	Missense	distal	4	no	11.534	10.720	EPSD	TCGA;ICGC;COSMIC	10.919	Loss
Other_PLK_PLK1_PLK1_ST	P11388	TOP2A	P53350	PLK1	S1115	S1117C	1117	Missense	proximal	2	no	13.258	12.286	EPSD	TCGA;ICGC;COSMIC	10.919	Down-regulation
Other_PLK_PLK1_PLK1_ST	P11388	TOP2A	P53350	PLK1	S1115	D1116N	1116	Missense	proximal	1	no	13.258	13.064	EPSD	TCGA;ICGC;COSMIC	10.919	Down-regulation
Other_PLK_PLK1_PLK1_ST	P11388	TOP2A	P53350	PLK1	S1115	S1117F	1117	Missense	proximal	2	no	13.258	12.707	EPSD	TCGA;ICGC;COSMIC	10.919	Down-regulation
Other_PLK_PLK1_PLK1_ST	P11388	TOP2A	P53350	PLK1	S1115	D1120Y	1120	Missense	distal	5	no	13.258	12.952	EPSD	TCGA;ICGC	10.919	Down-regulation
Other_PLK_PLK1_PLK1_ST	P11388	TOP2A	P53350	PLK1	S1117	S1117C	1117	Missense	central	0	yes	12.973	0.000	EPSD	TCGA;ICGC;COSMIC	10.919	Loss
Other_PLK_PLK1_PLK1_ST	P11388	TOP2A	P53350	PLK1	S1117	D1116N	1116	Missense	proximal	-1	no	12.973	12.040	EPSD	TCGA;ICGC;COSMIC	10.919	Down-regulation
Other_PLK_PLK1_PLK1_ST	P11388	TOP2A	P53350	PLK1	S1117	S1117F	1117	Missense	central	0	yes	12.973	0.000	EPSD	TCGA;ICGC;COSMIC	10.919	Loss
Other_PLK_PLK1_PLK1_ST	P11388	TOP2A	P53350	PLK1	S1117	D1120Y	1120	Missense	distal	3	no	12.973	12.547	EPSD	TCGA;ICGC	10.919	Down-regulation
Other_PLK_PLK1_PLK1_ST	P11388	TOP2A	P53350	PLK1	S1306	P1311S	1311	Missense	distal	5	no	11.267	10.880	EPSD	TCGA;ICGC;COSMIC	10.919	Loss
Other_PLK_PLK1_PLK1_ST	P11388	TOP2A	P53350	PLK1	S1332	F1336L	1336	Missense	distal	4	no	11.846	12.048	EPSD	TCGA;ICGC;COSMIC	10.919	Up-regulation
Other_PLK_PLK1_PLK1_ST	P11388	TOP2A	P53350	PLK1	S1337	F1336L	1336	Missense	proximal	-1	no	11.574	11.653	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	10.919	Up-regulation
Other_PLK_PLK1_PLK1_ST	P11388	TOP2A	P53350	PLK1	T1343	P1350L	1350	Missense	distal	7	no	11.725	11.697	PhosphoSitePlus;EPSD	TCGA	10.919	Down-regulation
Other_PLK_PLK1_PLK1_ST	P11388	TOP2A	P53350	PLK1	T1343	F1336L	1336	Missense	distal	-7	no	11.725	11.878	PhosphoSitePlus;EPSD	TCGA;ICGC;COSMIC	10.919	Up-regulation
Other_PLK_PLK1_PLK1_ST	P11388	TOP2A	P53350	PLK1	S1354	P1350L	1350	Missense	distal	-4	no	12.687	12.615	EPSD	TCGA	10.919	Down-regulation
Other_PLK_PLK1_PLK1_ST	P11388	TOP2A	P53350	PLK1	T1430	A1436D	1436	Missense	distal	6	no	11.178	11.166	EPSD	TCGA;ICGC;COSMIC	10.919	Down-regulation
Other_PLK_PLK1_PLK1_ST	P11388	TOP2A	P53350	PLK1	T1430	A1436V	1436	Missense	distal	6	no	11.178	11.003	EPSD	TCGA;ICGC;COSMIC	10.919	Down-regulation
Other_PLK_PLK1_PLK1_ST	P11388	TOP2A	P53350	PLK1	S1476	S1483L	1483	Missense	distal	7	no	11.082	11.080	EPSD	TCGA;ICGC;COSMIC	10.919	Down-regulation
Other_PLK_PLK1_PLK1_ST	P11388	TOP2A	P53350	PLK1	S1512	S1512F	1512	Missense	central	0	yes	11.979	0.000	EPSD	TCGA;ICGC;COSMIC;CCLE	10.919	Loss
Other_PLK_PLK1_PLK1_ST	Q9UBW7	ZMYM2	P53350	PLK1	S53	D59N	59	Missense	distal	6	no	12.847	12.627	EPSD	TCGA;ICGC;COSMIC	10.919	Down-regulation
Other_PLK_PLK1_PLK1_ST	Q9UBW7	ZMYM2	P53350	PLK1	S53	V60D	60	Missense	distal	7	no	12.847	12.772	EPSD	TCGA;ICGC;COSMIC	10.919	Down-regulation
Other_PLK_PLK1_PLK1_ST	Q9UBW7	ZMYM2	P53350	PLK1	S53	D56Y	56	Missense	distal	3	no	12.847	12.421	EPSD	TCGA;ICGC;COSMIC	10.919	Down-regulation
Other_PLK_PLK1_PLK1_ST	Q9UBW7	ZMYM2	P53350	PLK1	S136	E132D	132	Missense	distal	-4	no	11.403	11.219	EPSD	TCGA;ICGC;COSMIC	10.919	Down-regulation
Other_PLK_PLK1_PLK1_ST	Q9UBW7	ZMYM2	P53350	PLK1	S156	F160C	160	Missense	distal	4	no	10.884	11.171	EPSD	TCGA;ICGC;COSMIC	10.919	Gain
Other_PLK_PLK1_PLK1_ST	Q9UBW7	ZMYM2	P53350	PLK1	S159	S156F	156	Missense	distal	-3	no	13.793	13.163	EPSD	TCGA;ICGC;COSMIC	10.919	Down-regulation
Other_PLK_PLK1_PLK1_ST	Q9UBW7	ZMYM2	P53350	PLK1	S159	F160C	160	Missense	proximal	1	no	13.793	10.980	EPSD	TCGA;ICGC;COSMIC	10.919	Down-regulation
Other_PLK_PLK1_PLK1_ST	Q9UBW7	ZMYM2	P53350	PLK1	S303	A308T	308	Missense	distal	5	no	13.989	12.818	PhosphoSitePlus;EPSD	TCGA;ICGC;COSMIC	10.919	Down-regulation
Other_PLK_PLK1_PLK1_ST	Q9UBW7	ZMYM2	P53350	PLK1	S305	A308T	308	Missense	distal	3	no	10.895	10.934	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	10.919	Gain
Other_PLK_PLK1_PLK1_ST	Q9UBW7	ZMYM2	P53350	PLK1	S439	R435C	435	Missense	distal	-4	no	11.028	10.782	EPSD	TCGA;ICGC;COSMIC;CCLE	10.919	Loss
Other_PLK_PLK1_PLK1_ST	Q9UBW7	ZMYM2	P53350	PLK1	S522	M525I	525	Missense	distal	3	no	12.281	12.600	EPSD	TCGA;ICGC;COSMIC	10.919	Up-regulation
Other_PLK_PLK1_PLK1_ST	Q9UBW7	ZMYM2	P53350	PLK1	S1056	S1060G	1060	Missense	distal	4	no	12.321	12.236	EPSD	TCGA	10.919	Down-regulation
Other_PLK_PLK1_PLK1_ST	Q9UBW7	ZMYM2	P53350	PLK1	S1056	D1062H	1062	Missense	distal	6	no	12.321	11.527	EPSD	TCGA;ICGC;COSMIC	10.919	Down-regulation
Other_PLK_PLK1_PLK1_ST	Q9UBW7	ZMYM2	P53350	PLK1	S1061	S1060G	1060	Missense	proximal	-1	no	13.211	11.414	EPSD	TCGA	10.919	Down-regulation
Other_PLK_PLK1_PLK1_ST	Q9UBW7	ZMYM2	P53350	PLK1	S1061	D1062H	1062	Missense	proximal	1	no	13.211	12.509	EPSD	TCGA;ICGC;COSMIC	10.919	Down-regulation
Other_PLK_PLK1_PLK1_ST	Q9UBW7	ZMYM2	P53350	PLK1	S1067	S1060G	1060	Missense	distal	-7	no	12.667	11.971	EPSD	TCGA	10.919	Down-regulation
Other_PLK_PLK1_PLK1_ST	Q9UBW7	ZMYM2	P53350	PLK1	S1067	D1062H	1062	Missense	distal	-5	no	12.667	12.304	EPSD	TCGA;ICGC;COSMIC	10.919	Down-regulation
Other_PLK_PLK1_PLK1_ST	Q9UBW7	ZMYM2	P53350	PLK1	S1067	P1069H	1069	Missense	proximal	2	no	12.667	14.118	EPSD	TCGA;ICGC	10.919	Up-regulation
Other_PLK_PLK1_PLK1_ST	Q9UBW7	ZMYM2	P53350	PLK1	S1191	G1190E	1190	Missense	proximal	-1	no	9.782	11.576	EPSD	TCGA;COSMIC	10.919	Gain
Other_PLK_PLK1_PLK1_ST	Q9UBW7	ZMYM2	P53350	PLK1	T1376	D1375H	1375	Missense	proximal	-1	no	10.933	10.201	EPSD	TCGA;ICGC;COSMIC	10.919	Loss
Other_PLK_PLK1_PLK1_ST	Q9UBW7	ZMYM2	P53350	PLK1	T1376	T1376I	1376	Missense	central	0	yes	10.933	0.000	EPSD	TCGA;ICGC;COSMIC	10.919	Loss
Other_PLK_PLK1_PLK1_ST	Q9UBW7	ZMYM2	P53350	PLK1	T1376	T1376R	1376	Missense	central	0	yes	10.933	0.000	EPSD	TCGA;ICGC;COSMIC	10.919	Loss
Other_PLK_PLK1_PLK1_ST	Q8NHV4	NEDD1	P53350	PLK1	T382	T387R	387	Missense	distal	5	no	13.757	14.706	EPSD;PhosphoSitePlus	TCGA;COSMIC	10.919	Up-regulation
Other_PLK_PLK1_PLK1_ST	Q8NHV4	NEDD1	P53350	PLK1	S637	H630Y	630	Missense	distal	-7	no	12.013	11.518	PhosphoSitePlus;EPSD	TCGA;COSMIC	10.919	Down-regulation
Other_PLK_PLK1_PLK1_ST	Q13042	CDC16	P53350	PLK1	S112	D116Y	116	Missense	distal	4	no	12.015	11.769	PhosphoSitePlus	TCGA;ICGC;COSMIC	10.919	Down-regulation
Other_PLK_PLK1_PLK1_ST	Q13042	CDC16	P53350	PLK1	S112	K106N	106	Missense	distal	-6	no	12.015	12.273	PhosphoSitePlus	TCGA;ICGC;COSMIC	10.919	Up-regulation
Other_PLK_PLK1_PLK1_ST	Q13042	CDC16	P53350	PLK1	S118	M123L	123	Missense	distal	5	no	11.095	10.652	EPSD	TCGA;ICGC;COSMIC	10.919	Loss
Other_PLK_PLK1_PLK1_ST	Q13042	CDC16	P53350	PLK1	S118	D116Y	116	Missense	proximal	-2	no	11.095	9.553	EPSD	TCGA;ICGC;COSMIC	10.919	Loss
Other_PLK_PLK1_PLK1_ST	Q13042	CDC16	P53350	PLK1	S124	M123L	123	Missense	proximal	-1	no	11.071	10.540	EPSD	TCGA;ICGC;COSMIC	10.919	Loss
Other_PLK_PLK1_PLK1_ST	Q13042	CDC16	P53350	PLK1	S324	H318R	318	Missense	distal	-6	no	11.458	10.999	EPSD	TCGA;ICGC;COSMIC	10.919	Down-regulation
Other_PLK_PLK1_PLK1_ST	Q13042	CDC16	P53350	PLK1	S324	A319V	319	Missense	distal	-5	no	11.458	11.385	EPSD	TCGA;ICGC	10.919	Down-regulation
Other_PLK_PLK1_PLK1_ST	Q13042	CDC16	P53350	PLK1	T440	P446R	446	Missense	distal	6	no	12.051	11.600	EPSD	TCGA	10.919	Down-regulation
Other_PLK_PLK1_PLK1_ST	Q13042	CDC16	P53350	PLK1	T440	D442G	442	Missense	proximal	2	no	12.051	10.472	EPSD	TCGA;ICGC;COSMIC	10.919	Loss
Other_PLK_PLK1_PLK1_ST	Q13042	CDC16	P53350	PLK1	T599	E603K	603	Missense	distal	4	no	17.407	17.033	EPSD	TCGA;ICGC;COSMIC	10.919	Down-regulation
Other_PLK_PLK1_PLK1_ST	Q13042	CDC16	P53350	PLK1	S607	M609I	609	Missense	proximal	2	no	14.099	14.522	EPSD	TCGA;ICGC;COSMIC	10.919	Up-regulation
Other_PLK_PLK1_PLK1_ST	Q13042	CDC16	P53350	PLK1	S607	E603K	603	Missense	distal	-4	no	14.099	13.716	EPSD	TCGA;ICGC;COSMIC	10.919	Down-regulation
Other_PLK_PLK1_PLK1_ST	Q13042	CDC16	P53350	PLK1	S614	D617H	617	Missense	distal	3	no	14.760	14.522	EPSD	TCGA;ICGC;COSMIC	10.919	Down-regulation
Other_PLK_PLK1_PLK1_ST	Q13042	CDC16	P53350	PLK1	S614	M609I	609	Missense	distal	-5	no	14.760	15.064	EPSD	TCGA;ICGC;COSMIC	10.919	Up-regulation
Other_PLK_PLK1_PLK1_ST	Q13042	CDC16	P53350	PLK1	S616	D617H	617	Missense	proximal	1	no	11.096	10.394	EPSD	TCGA;ICGC;COSMIC	10.919	Loss
Other_PLK_PLK1_PLK1_ST	Q13042	CDC16	P53350	PLK1	S616	M609I	609	Missense	distal	-7	no	11.096	11.064	EPSD	TCGA;ICGC;COSMIC	10.919	Down-regulation
Other_PLK_PLK1_PLK1_ST	Q13042	CDC16	P53350	PLK1	S619	D617H	617	Missense	proximal	-2	no	11.703	8.516	EPSD	TCGA;ICGC;COSMIC	10.919	Loss
Other_PLK_PLK1_PLK1_ST	P18031	PTPN1	P53350	PLK1	S50	D53H	53	Missense	distal	3	no	15.413	15.175	EPSD	TCGA;COSMIC	10.919	Down-regulation
Other_PLK_PLK1_PLK1_ST	P18031	PTPN1	P53350	PLK1	S50	Y46H	46	Missense	distal	-4	no	15.413	15.834	EPSD	TCGA;ICGC;COSMIC	10.919	Up-regulation
Other_PLK_PLK1_PLK1_ST	P18031	PTPN1	P53350	PLK1	S50	D48Y	48	Missense	proximal	-2	no	15.413	13.871	EPSD	TCGA;ICGC;COSMIC	10.919	Down-regulation
Other_PLK_PLK1_PLK1_ST	P18031	PTPN1	P53350	PLK1	S50	P51L	51	Missense	proximal	1	no	15.413	16.259	EPSD	TCGA;ICGC	10.919	Up-regulation
Other_PLK_PLK1_PLK1_ST	P18031	PTPN1	P53350	PLK1	S50	R43Q	43	Missense	distal	-7	no	15.413	15.813	EPSD	TCGA;ICGC	10.919	Up-regulation
Other_PLK_PLK1_PLK1_ST	P18031	PTPN1	P53350	PLK1	S286	M282T	282	Missense	distal	-4	no	14.986	14.900	PhosphoSitePlus;EPSD	TCGA;COSMIC	10.919	Down-regulation
Other_PLK_PLK1_PLK1_ST	P18031	PTPN1	P53350	PLK1	S378	V375L	375	Missense	distal	-3	no	10.600	11.250	EPSD	TCGA;COSMIC	10.919	Gain
Other_PLK_PLK1_PLK1_ST	P18031	PTPN1	P53350	PLK1	S393	D398Y	398	Missense	distal	5	no	11.750	11.444	EPSD;PhosphoSitePlus	TCGA;COSMIC	10.919	Down-regulation
Other_PLK_PLK1_PLK1_ST	P18031	PTPN1	P53350	PLK1	S393	S386F	386	Missense	distal	-7	no	11.750	11.293	EPSD;PhosphoSitePlus	TCGA;COSMIC	10.919	Down-regulation
Other_PLK_PLK1_PLK1_ST	Q8N4N8	KIF2B	P53350	PLK1	T125	P120R	120	Missense	distal	-5	no	11.675	12.096	PhosphoSitePlus;EPSD	TCGA	10.919	Up-regulation
Other_PLK_PLK1_PLK1_ST	Q8N4N8	KIF2B	P53350	PLK1	T125	P120T	120	Missense	distal	-5	no	11.675	11.627	PhosphoSitePlus;EPSD	TCGA;ICGC;COSMIC	10.919	Down-regulation
Other_PLK_PLK1_PLK1_ST	Q8N4N8	KIF2B	P53350	PLK1	T125	L131M	131	Missense	distal	6	no	11.675	11.381	PhosphoSitePlus;EPSD	TCGA;ICGC;COSMIC	10.919	Down-regulation
Other_PLK_PLK1_PLK1_ST	Q8N4N8	KIF2B	P53350	PLK1	T125	M118I	118	Missense	distal	-7	no	11.675	11.643	PhosphoSitePlus;EPSD	TCGA;ICGC;COSMIC	10.919	Down-regulation
Other_PLK_PLK1_PLK1_ST	Q8N4N8	KIF2B	P53350	PLK1	T125	D129N	129	Missense	distal	4	no	11.675	11.436	PhosphoSitePlus;EPSD	TCGA;ICGC;COSMIC	10.919	Down-regulation
Other_PLK_PLK1_PLK1_ST	Q8N4N8	KIF2B	P53350	PLK1	S444	V446I	446	Missense	proximal	2	no	10.813	11.031	EPSD	TCGA;ICGC;COSMIC;CCLE	10.919	Gain
Other_PLK_PLK1_PLK1_ST	Q8N4N8	KIF2B	P53350	PLK1	S444	R437Q	437	Missense	distal	-7	no	10.813	11.214	EPSD	TCGA;ICGC;COSMIC	10.919	Gain
Other_PLK_PLK1_PLK1_ST	Q8N4N8	KIF2B	P53350	PLK1	S444	M439R	439	Missense	distal	-5	no	10.813	11.433	EPSD	TCGA	10.919	Gain
Other_PLK_PLK1_PLK1_ST	Q8N4N8	KIF2B	P53350	PLK1	S474	A477T	477	Missense	distal	3	no	12.257	12.296	EPSD	TCGA;ICGC;COSMIC	10.919	Up-regulation
Other_PLK_PLK1_PLK1_ST	Q8N4N8	KIF2B	P53350	PLK1	S474	E467Q	467	Missense	distal	-7	no	12.257	12.221	EPSD	TCGA;ICGC;COSMIC	10.919	Down-regulation
Other_PLK_PLK1_PLK1_ST	Q8N4N8	KIF2B	P53350	PLK1	S474	K473R	473	Missense	proximal	-1	no	12.257	11.895	EPSD	TCGA;ICGC;COSMIC	10.919	Down-regulation
Other_PLK_PLK1_PLK1_ST	Q8N4N8	KIF2B	P53350	PLK1	S474	A477V	477	Missense	distal	3	no	12.257	12.585	EPSD	TCGA;ICGC;COSMIC;GDSC;CCLE	10.919	Up-regulation
Other_PLK_PLK1_PLK1_ST	Q8N4N8	KIF2B	P53350	PLK1	S474	A469E	469	Missense	distal	-5	no	12.257	11.875	EPSD	TCGA;ICGC;COSMIC	10.919	Down-regulation
Other_PLK_PLK1_PLK1_ST	Q8N4N8	KIF2B	P53350	PLK1	S474	E470D	470	Missense	distal	-4	no	12.257	12.073	EPSD	TCGA;ICGC;COSMIC	10.919	Down-regulation
Other_PLK_PLK1_PLK1_ST	Q8N4N8	KIF2B	P53350	PLK1	S474	E480K	480	Missense	distal	6	no	12.257	12.188	EPSD	TCGA;ICGC;COSMIC	10.919	Down-regulation
Other_PLK_PLK1_PLK1_ST	Q8N4N8	KIF2B	P53350	PLK1	S474	L475I	475	Missense	proximal	1	no	12.257	12.048	EPSD	TCGA;ICGC;COSMIC	10.919	Down-regulation
Other_PLK_PLK1_PLK1_ST	Q8N4N8	KIF2B	P53350	PLK1	S575	D579N	579	Missense	distal	4	no	11.721	11.482	EPSD	TCGA;ICGC;COSMIC	10.919	Down-regulation
Other_PLK_PLK1_PLK1_ST	Q8N4N8	KIF2B	P53350	PLK1	S575	S572L	572	Missense	distal	-3	no	11.721	12.495	EPSD	TCGA;ICGC;COSMIC	10.919	Up-regulation
Other_PLK_PLK1_PLK1_ST	Q8N4N8	KIF2B	P53350	PLK1	S575	G570R	570	Missense	distal	-5	no	11.721	12.006	EPSD	TCGA;ICGC;COSMIC	10.919	Up-regulation
Other_PLK_PLK1_PLK1_ST	Q8N4N8	KIF2B	P53350	PLK1	S575	R578K	578	Missense	distal	3	no	11.721	11.818	EPSD	TCGA;ICGC;COSMIC	10.919	Up-regulation
Other_PLK_PLK1_PLK1_ST	Q8N4N8	KIF2B	P53350	PLK1	T610	G613W	613	Missense	distal	3	no	11.387	11.031	EPSD	TCGA;ICGC;COSMIC	10.919	Down-regulation
Other_PLK_PLK1_PLK1_ST	Q8N4N8	KIF2B	P53350	PLK1	T610	D608G	608	Missense	proximal	-2	no	11.387	8.065	EPSD	TCGA;ICGC;COSMIC	10.919	Loss
Other_PLK_PLK1_PLK1_ST	Q8N4N8	KIF2B	P53350	PLK1	T610	S617G	617	Missense	distal	7	no	11.387	11.385	EPSD	TCGA;ICGC;COSMIC	10.919	Down-regulation
Other_PLK_PLK1_PLK1_ST	Q8N4N8	KIF2B	P53350	PLK1	T610	G606R	606	Missense	distal	-4	no	11.387	11.474	EPSD	TCGA;ICGC;COSMIC	10.919	Up-regulation
Other_PLK_PLK1_PLK1_ST	Q8N4N8	KIF2B	P53350	PLK1	T610	D608N	608	Missense	proximal	-2	no	11.387	10.144	EPSD	TCGA;ICGC;COSMIC	10.919	Loss
Other_PLK_PLK1_PLK1_ST	Q8N4N8	KIF2B	P53350	PLK1	T610	G613E	613	Missense	distal	3	no	11.387	11.564	EPSD	TCGA;ICGC;COSMIC	10.919	Up-regulation
Other_PLK_PLK1_PLK1_ST	Q9Y5T5	USP16	P53350	PLK1	S16	P12L	12	Missense	distal	-4	no	13.082	13.011	EPSD	TCGA;ICGC	10.919	Down-regulation
Other_PLK_PLK1_PLK1_ST	Q9Y5T5	USP16	P53350	PLK1	S17	P12L	12	Missense	distal	-5	no	14.836	15.237	EPSD	TCGA;ICGC	10.919	Up-regulation
Other_PLK_PLK1_PLK1_ST	Q9Y5T5	USP16	P53350	PLK1	S353	F359L	359	Missense	distal	6	no	10.779	11.395	EPSD	TCGA;COSMIC	10.919	Gain
Other_PLK_PLK1_PLK1_ST	Q9Y5T5	USP16	P53350	PLK1	S353	R357H	357	Missense	distal	4	no	10.779	11.203	EPSD	TCGA	10.919	Gain
Other_PLK_PLK1_PLK1_ST	Q9Y5T5	USP16	P53350	PLK1	S423	E427Q	427	Missense	distal	4	no	10.964	10.561	EPSD	TCGA;COSMIC	10.919	Loss
Other_PLK_PLK1_PLK1_ST	Q9Y5T5	USP16	P53350	PLK1	S423	D430Y	430	Missense	distal	7	no	10.964	11.046	EPSD	TCGA;COSMIC	10.919	Up-regulation
Other_PLK_PLK1_PLK1_ST	Q9Y5T5	USP16	P53350	PLK1	S423	R428K	428	Missense	distal	5	no	10.964	10.339	EPSD	TCGA;COSMIC	10.919	Loss
Other_PLK_PLK1_PLK1_ST	Q9Y5T5	USP16	P53350	PLK1	S423	R428I	428	Missense	distal	5	no	10.964	10.918	EPSD	TCGA	10.919	Loss
Other_PLK_PLK1_PLK1_ST	Q9Y5T5	USP16	P53350	PLK1	S486	N492S	492	Missense	distal	6	no	13.918	13.867	EPSD;PhosphoSitePlus	TCGA;COSMIC	10.919	Down-regulation
Other_PLK_PLK1_PLK1_ST	O14641	DVL2	P53350	PLK1	T39	R37L	37	Missense	proximal	-2	no	12.315	11.593	EPSD	TCGA;ICGC;COSMIC	10.919	Down-regulation
Other_PLK_PLK1_PLK1_ST	O14641	DVL2	P53350	PLK1	S170	R165H	165	Missense	distal	-5	no	13.804	13.002	EPSD	TCGA;ICGC;COSMIC	10.919	Down-regulation
Other_PLK_PLK1_PLK1_ST	O14641	DVL2	P53350	PLK1	T216	S218I	218	Missense	proximal	2	no	13.308	13.729	EPSD	TCGA;ICGC;COSMIC	10.919	Up-regulation
Other_PLK_PLK1_PLK1_ST	O14641	DVL2	P53350	PLK1	T216	D215Y	215	Missense	proximal	-1	no	13.308	12.851	EPSD	TCGA;ICGC;COSMIC	10.919	Down-regulation
Other_PLK_PLK1_PLK1_ST	O14641	DVL2	P53350	PLK1	T250	R246H	246	Missense	distal	-4	no	12.068	12.369	EPSD	TCGA;ICGC;COSMIC	10.919	Up-regulation
Other_PLK_PLK1_PLK1_ST	O14641	DVL2	P53350	PLK1	T250	R246C	246	Missense	distal	-4	no	12.068	11.822	EPSD	TCGA;ICGC;COSMIC	10.919	Down-regulation
Other_PLK_PLK1_PLK1_ST	O14641	DVL2	P53350	PLK1	T250	P245L	245	Missense	distal	-5	no	12.068	12.469	EPSD	TCGA;ICGC;COSMIC	10.919	Up-regulation
Other_PLK_PLK1_PLK1_ST	O14641	DVL2	P53350	PLK1	S252	R246H	246	Missense	distal	-6	no	13.628	14.087	EPSD	TCGA;ICGC;COSMIC	10.919	Up-regulation
Other_PLK_PLK1_PLK1_ST	O14641	DVL2	P53350	PLK1	S252	R246C	246	Missense	distal	-6	no	13.628	12.872	EPSD	TCGA;ICGC;COSMIC	10.919	Down-regulation
Other_PLK_PLK1_PLK1_ST	O14641	DVL2	P53350	PLK1	S252	P245L	245	Missense	distal	-7	no	13.628	13.533	EPSD	TCGA;ICGC;COSMIC	10.919	Down-regulation
Other_PLK_PLK1_PLK1_ST	O14641	DVL2	P53350	PLK1	S252	D258Y	258	Missense	distal	6	no	13.628	12.829	EPSD	TCGA;ICGC	10.919	Down-regulation
Other_PLK_PLK1_PLK1_ST	O14641	DVL2	P53350	PLK1	S298	I294M	294	Missense	distal	-4	no	11.590	11.280	EPSD	TCGA;ICGC;COSMIC	10.919	Down-regulation
Other_PLK_PLK1_PLK1_ST	O14641	DVL2	P53350	PLK1	S298	M300I	300	Missense	proximal	2	no	11.590	12.014	EPSD	TCGA;ICGC;COSMIC	10.919	Up-regulation
Other_PLK_PLK1_PLK1_ST	O14641	DVL2	P53350	PLK1	S358	Q360H	360	Missense	proximal	2	no	10.595	10.973	EPSD	TCGA;ICGC;COSMIC	10.919	Gain
Other_PLK_PLK1_PLK1_ST	O14641	DVL2	P53350	PLK1	T364	R367L	367	Missense	distal	3	no	11.285	11.262	EPSD	TCGA;ICGC;COSMIC	10.919	Down-regulation
Other_PLK_PLK1_PLK1_ST	O14641	DVL2	P53350	PLK1	T364	R367Q	367	Missense	distal	3	no	11.285	11.481	EPSD	TCGA;ICGC;COSMIC	10.919	Up-regulation
Other_PLK_PLK1_PLK1_ST	O14641	DVL2	P53350	PLK1	T364	P359H	359	Missense	distal	-5	no	11.285	10.904	EPSD	TCGA;ICGC;COSMIC	10.919	Loss
Other_PLK_PLK1_PLK1_ST	O14641	DVL2	P53350	PLK1	T364	Q360H	360	Missense	distal	-4	no	11.285	11.298	EPSD	TCGA;ICGC;COSMIC	10.919	Up-regulation
Other_PLK_PLK1_PLK1_ST	O14641	DVL2	P53350	PLK1	S398	S397F	397	Missense	proximal	-1	no	11.555	11.016	EPSD	TCGA;ICGC	10.919	Down-regulation
Other_PLK_PLK1_PLK1_ST	O14641	DVL2	P53350	PLK1	S398	S398F	398	Missense	central	0	yes	11.555	0.000	EPSD	TCGA;ICGC;COSMIC	10.919	Loss
Other_PLK_PLK1_PLK1_ST	O14641	DVL2	P53350	PLK1	S398	G395D	395	Missense	distal	-3	no	11.555	11.073	EPSD	TCGA;ICGC;COSMIC	10.919	Down-regulation
Other_PLK_PLK1_PLK1_ST	O14641	DVL2	P53350	PLK1	S480	R473W	473	Missense	distal	-7	no	10.672	11.258	EPSD	TCGA;ICGC;COSMIC	10.919	Gain
Other_PLK_PLK1_PLK1_ST	O14641	DVL2	P53350	PLK1	S480	R476H	476	Missense	distal	-4	no	10.672	10.974	EPSD	TCGA;ICGC;COSMIC;GDSC;CCLE	10.919	Gain
Other_PLK_PLK1_PLK1_ST	O14641	DVL2	P53350	PLK1	S638	R632W	632	Missense	distal	-6	no	12.252	11.796	EPSD	TCGA;ICGC;COSMIC	10.919	Down-regulation
Other_PLK_PLK1_PLK1_ST	O14641	DVL2	P53350	PLK1	S720	M725T	725	Missense	distal	5	no	12.586	11.884	EPSD	TCGA;ICGC;COSMIC	10.919	Down-regulation
Other_PLK_PLK1_PLK1_ST	Q3KR16	PLEKHG6	P53350	PLK1	T184	R178I	178	Missense	distal	-6	no	10.488	11.004	EPSD	TCGA;ICGC;COSMIC	10.919	Gain
Other_PLK_PLK1_PLK1_ST	Q3KR16	PLEKHG6	P53350	PLK1	T574	D575Y	575	Missense	proximal	1	no	15.143	14.946	PhosphoSitePlus	TCGA;ICGC;COSMIC	10.919	Down-regulation
Other_PLK_PLK1_PLK1_ST	Q3KR16	PLEKHG6	P53350	PLK1	T574	V581A	581	Missense	distal	7	no	15.143	15.121	PhosphoSitePlus	TCGA;ICGC;COSMIC	10.919	Down-regulation
Other_PLK_PLK1_PLK1_ST	Q3KR16	PLEKHG6	P53350	PLK1	S712	E710K	710	Missense	proximal	-2	no	12.486	9.609	EPSD	TCGA;ICGC;COSMIC	10.919	Loss
Other_PLK_PLK1_PLK1_ST	Q9H2D6	TRIOBP	P53350	PLK1	S245	T241A	241	Missense	distal	-4	no	11.639	12.041	EPSD	TCGA;ICGC	10.919	Up-regulation
Other_PLK_PLK1_PLK1_ST	Q9H2D6	TRIOBP	P53350	PLK1	S324	E317V	317	Missense	distal	-7	no	11.428	11.192	EPSD	TCGA;ICGC;COSMIC	10.919	Down-regulation
Other_PLK_PLK1_PLK1_ST	Q9H2D6	TRIOBP	P53350	PLK1	S588	S589F	589	Missense	proximal	1	no	8.409	11.457	EPSD	TCGA;ICGC;COSMIC	10.919	Gain
Other_PLK_PLK1_PLK1_ST	Q9H2D6	TRIOBP	P53350	PLK1	S589	P590L	590	Missense	proximal	1	no	10.497	11.342	EPSD	TCGA;ICGC;COSMIC	10.919	Gain
Other_PLK_PLK1_PLK1_ST	Q9H2D6	TRIOBP	P53350	PLK1	S856	S858F	858	Missense	proximal	2	no	14.205	13.654	EPSD	TCGA;ICGC;COSMIC	10.919	Down-regulation
Other_PLK_PLK1_PLK1_ST	Q9H2D6	TRIOBP	P53350	PLK1	S1124	R1127C	1127	Missense	distal	3	no	11.761	11.821	EPSD	TCGA;ICGC;COSMIC	10.919	Up-regulation
Other_PLK_PLK1_PLK1_ST	Q9H2D6	TRIOBP	P53350	PLK1	S1124	R1121Q	1121	Missense	distal	-3	no	11.761	11.086	EPSD	TCGA;ICGC;COSMIC	10.919	Down-regulation
Other_PLK_PLK1_PLK1_ST	Q9H2D6	TRIOBP	P53350	PLK1	S1124	D1118Y	1118	Missense	distal	-6	no	11.761	10.992	EPSD	TCGA;ICGC;COSMIC	10.919	Down-regulation
Other_PLK_PLK1_PLK1_ST	Q9H2D6	TRIOBP	P53350	PLK1	S1124	P1125L	1125	Missense	proximal	1	no	11.761	12.607	EPSD	TCGA;ICGC;COSMIC	10.919	Up-regulation
Other_PLK_PLK1_PLK1_ST	Q9H2D6	TRIOBP	P53350	PLK1	S1133	R1127C	1127	Missense	distal	-6	no	11.981	11.226	EPSD	TCGA;ICGC;COSMIC	10.919	Down-regulation
Other_PLK_PLK1_PLK1_ST	Q9H2D6	TRIOBP	P53350	PLK1	S1900	D1893G	1893	Missense	distal	-7	no	12.527	12.181	EPSD	TCGA;ICGC;COSMIC	10.919	Down-regulation
Other_PLK_PLK1_PLK1_ST	Q9H2D6	TRIOBP	P53350	PLK1	S2091	G2086R	2086	Missense	distal	-5	no	11.860	12.145	EPSD	TCGA;ICGC;COSMIC	10.919	Up-regulation
Other_PLK_PLK1_PLK1_ST	Q9H2D6	TRIOBP	P53350	PLK1	S2091	P2089H	2089	Missense	proximal	-2	no	11.860	11.909	EPSD	TCGA;ICGC	10.919	Up-regulation
Other_PLK_PLK1_PLK1_ST	Q9H2D6	TRIOBP	P53350	PLK1	T2229	E2224K	2224	Missense	distal	-5	no	11.598	11.841	EPSD	TCGA;ICGC;COSMIC	10.919	Up-regulation
Other_PLK_PLK1_PLK1_ST	Q9H2D6	TRIOBP	P53350	PLK1	S2329	R2334L	2334	Missense	distal	5	no	12.366	11.675	EPSD	TCGA;ICGC;COSMIC	10.919	Down-regulation
Other_PLK_PLK1_PLK1_ST	Q9H2D6	TRIOBP	P53350	PLK1	S2358	R2360H	2360	Missense	proximal	2	no	11.157	11.859	EPSD	TCGA;ICGC;COSMIC	10.919	Up-regulation
Other_PLK_PLK1_PLK1_ST	Q9H2D6	TRIOBP	P53350	PLK1	S2362	R2360H	2360	Missense	proximal	-2	no	11.432	11.123	EPSD	TCGA;ICGC;COSMIC	10.919	Down-regulation
Other_PLK_PLK1_PLK1_ST	Q00839	HNRNPU	P53350	PLK1	S59	G58C	58	Missense	proximal	-1	no	11.335	11.272	PhosphoSitePlus	TCGA;ICGC;COSMIC	10.919	Down-regulation
Other_PLK_PLK1_PLK1_ST	Q00839	HNRNPU	P53350	PLK1	T286	E279D	279	Missense	distal	-7	no	13.810	13.521	EPSD	TCGA;ICGC;COSMIC	10.919	Down-regulation
Other_PLK_PLK1_PLK1_ST	Q00839	HNRNPU	P53350	PLK1	T286	D291H	291	Missense	distal	5	no	13.810	13.354	EPSD	TCGA;ICGC;COSMIC	10.919	Down-regulation
Other_PLK_PLK1_PLK1_ST	Q00839	HNRNPU	P53350	PLK1	T474	P468S	468	Missense	distal	-6	no	13.648	14.271	EPSD	TCGA;ICGC;COSMIC	10.919	Up-regulation
Other_PLK_PLK1_PLK1_ST	Q00839	HNRNPU	P53350	PLK1	T474	I469T	469	Missense	distal	-5	no	13.648	13.495	EPSD	TCGA;ICGC;COSMIC	10.919	Down-regulation
Other_PLK_PLK1_PLK1_ST	Q00839	HNRNPU	P53350	PLK1	T474	E472D	472	Missense	proximal	-2	no	13.648	14.042	EPSD	TCGA;ICGC;COSMIC	10.919	Up-regulation
Other_PLK_PLK1_PLK1_ST	Q00839	HNRNPU	P53350	PLK1	T582	R575Q	575	Missense	distal	-7	no	11.635	12.036	EPSD	TCGA;ICGC;COSMIC	10.919	Up-regulation
Other_PLK_PLK1_PLK1_ST	Q00839	HNRNPU	P53350	PLK1	T582	N576H	576	Missense	distal	-6	no	11.635	11.844	EPSD	TCGA;ICGC;COSMIC	10.919	Up-regulation
Other_PLK_PLK1_PLK1_ST	Q9NS56	TOPORS	P53350	PLK1	S65	S70L	70	Missense	distal	5	no	11.259	10.913	EPSD	TCGA;COSMIC	10.919	Loss
Other_PLK_PLK1_PLK1_ST	Q9NS56	TOPORS	P53350	PLK1	S98	D96N	96	Missense	proximal	-2	no	11.935	10.692	EPSD	TCGA;COSMIC	10.919	Loss
Other_PLK_PLK1_PLK1_ST	Q9NS56	TOPORS	P53350	PLK1	S98	A95V	95	Missense	distal	-3	no	11.935	11.536	EPSD	TCGA;COSMIC	10.919	Down-regulation
Other_PLK_PLK1_PLK1_ST	Q9NS56	TOPORS	P53350	PLK1	S98	V93L	93	Missense	distal	-5	no	11.935	12.387	EPSD	TCGA;COSMIC	10.919	Up-regulation
Other_PLK_PLK1_PLK1_ST	Q9NS56	TOPORS	P53350	PLK1	S98	D100N	100	Missense	proximal	2	no	11.935	12.149	EPSD	TCGA;COSMIC	10.919	Up-regulation
Other_PLK_PLK1_PLK1_ST	Q9NS56	TOPORS	P53350	PLK1	S98	I105M	105	Missense	distal	7	no	11.935	11.971	EPSD	TCGA;COSMIC	10.919	Up-regulation
Other_PLK_PLK1_PLK1_ST	Q9NS56	TOPORS	P53350	PLK1	S98	I105T	105	Missense	distal	7	no	11.935	11.888	EPSD	TCGA	10.919	Down-regulation
Other_PLK_PLK1_PLK1_ST	Q9NS56	TOPORS	P53350	PLK1	S98	V93E	93	Missense	distal	-5	no	11.935	11.626	EPSD	TCGA;COSMIC	10.919	Down-regulation
Other_PLK_PLK1_PLK1_ST	Q9NS56	TOPORS	P53350	PLK1	S114	R118H	118	Missense	distal	4	no	10.507	10.931	EPSD	TCGA;COSMIC	10.919	Gain
Other_PLK_PLK1_PLK1_ST	Q9NS56	TOPORS	P53350	PLK1	S170	D175N	175	Missense	distal	5	no	12.195	11.442	EPSD	TCGA;COSMIC	10.919	Down-regulation
Other_PLK_PLK1_PLK1_ST	Q9NS56	TOPORS	P53350	PLK1	S170	T173A	173	Missense	distal	3	no	12.195	12.156	EPSD	TCGA;COSMIC	10.919	Down-regulation
Other_PLK_PLK1_PLK1_ST	Q9NS56	TOPORS	P53350	PLK1	S191	R188Q	188	Missense	distal	-3	no	12.463	11.788	EPSD	TCGA;COSMIC	10.919	Down-regulation
Other_PLK_PLK1_PLK1_ST	Q9NS56	TOPORS	P53350	PLK1	S191	P198H	198	Missense	distal	7	no	12.463	12.422	EPSD	TCGA;COSMIC	10.919	Down-regulation
Other_PLK_PLK1_PLK1_ST	Q9NS56	TOPORS	P53350	PLK1	S194	R188Q	188	Missense	distal	-6	no	10.623	11.071	EPSD	TCGA;COSMIC	10.919	Gain
Other_PLK_PLK1_PLK1_ST	Q9NS56	TOPORS	P53350	PLK1	S498	S501F	501	Missense	distal	3	no	11.379	11.439	EPSD	TCGA;COSMIC	10.919	Up-regulation
Other_PLK_PLK1_PLK1_ST	Q9NS56	TOPORS	P53350	PLK1	S635	R628Q	628	Missense	distal	-7	no	10.606	11.006	EPSD	TCGA;COSMIC	10.919	Gain
Other_PLK_PLK1_PLK1_ST	Q9NS56	TOPORS	P53350	PLK1	S718	S719F	719	Missense	proximal	1	no	8.122	11.170	PhosphoSitePlus	TCGA;COSMIC	10.919	Gain
Other_PLK_PLK1_PLK1_ST	Q9NS56	TOPORS	P53350	PLK1	S771	Y764S	764	Missense	distal	-7	no	11.905	12.517	EPSD	TCGA;COSMIC	10.919	Up-regulation
Other_PLK_PLK1_PLK1_ST	Q9NS56	TOPORS	P53350	PLK1	T842	N835S	835	Missense	distal	-7	no	12.391	12.601	EPSD	TCGA;COSMIC	10.919	Up-regulation
Other_PLK_PLK1_PLK1_ST	Q9NS56	TOPORS	P53350	PLK1	S866	S864N	864	Missense	proximal	-2	no	11.044	12.454	EPSD	TCGA;COSMIC	10.919	Up-regulation
Other_PLK_PLK1_PLK1_ST	Q9NS56	TOPORS	P53350	PLK1	S866	R863Q	863	Missense	distal	-3	no	11.044	10.370	EPSD	TCGA;COSMIC	10.919	Loss
Other_PLK_PLK1_PLK1_ST	Q9NS56	TOPORS	P53350	PLK1	S914	S918F	918	Missense	distal	4	no	11.879	11.065	EPSD	TCGA;COSMIC	10.919	Down-regulation
Other_PLK_PLK1_PLK1_ST	Q9NS56	TOPORS	P53350	PLK1	S914	D917N	917	Missense	distal	3	no	11.879	11.679	EPSD	TCGA;COSMIC	10.919	Down-regulation
Other_PLK_PLK1_PLK1_ST	Q9NS56	TOPORS	P53350	PLK1	S914	K916N	916	Missense	proximal	2	no	11.879	12.854	EPSD	TCGA	10.919	Up-regulation
Other_PLK_PLK1_PLK1_ST	Q9NS56	TOPORS	P53350	PLK1	S914	S918Y	918	Missense	distal	4	no	11.879	11.636	EPSD	TCGA;COSMIC	10.919	Down-regulation
Other_PLK_PLK1_PLK1_ST	Q9NS56	TOPORS	P53350	PLK1	S918	S918F	918	Missense	central	0	yes	11.532	0.000	EPSD	TCGA;COSMIC	10.919	Loss
Other_PLK_PLK1_PLK1_ST	Q9NS56	TOPORS	P53350	PLK1	S918	E925Q	925	Missense	distal	7	no	11.532	11.585	EPSD	TCGA;COSMIC	10.919	Up-regulation
Other_PLK_PLK1_PLK1_ST	Q9NS56	TOPORS	P53350	PLK1	S918	D917N	917	Missense	proximal	-1	no	11.532	10.599	EPSD	TCGA;COSMIC	10.919	Loss
Other_PLK_PLK1_PLK1_ST	Q9NS56	TOPORS	P53350	PLK1	S918	K916N	916	Missense	proximal	-2	no	11.532	13.561	EPSD	TCGA	10.919	Up-regulation
Other_PLK_PLK1_PLK1_ST	Q9NS56	TOPORS	P53350	PLK1	S918	S918Y	918	Missense	central	0	yes	11.532	0.000	EPSD	TCGA;COSMIC	10.919	Loss
Other_PLK_PLK1_PLK1_ST	Q9NS56	TOPORS	P53350	PLK1	S918	T924I	924	Missense	distal	6	no	11.532	11.258	EPSD	TCGA;COSMIC	10.919	Down-regulation
Other_PLK_PLK1_PLK1_ST	Q9NS56	TOPORS	P53350	PLK1	S1013	P1012L	1012	Missense	proximal	-1	no	10.719	11.433	EPSD	TCGA;COSMIC	10.919	Gain
Other_PLK_PLK1_PLK1_ST	Q9NS56	TOPORS	P53350	PLK1	S1017	S1013I	1013	Missense	distal	-4	no	12.143	12.176	EPSD	TCGA	10.919	Up-regulation
Other_PLK_PLK1_PLK1_ST	Q9NS56	TOPORS	P53350	PLK1	S1017	P1012L	1012	Missense	distal	-5	no	12.143	12.544	EPSD	TCGA;COSMIC	10.919	Up-regulation
Other_PLK_PLK1_PLK1_ST	Q9NS56	TOPORS	P53350	PLK1	S1017	N1014T	1014	Missense	distal	-3	no	12.143	12.329	EPSD	TCGA	10.919	Up-regulation
Other_PLK_PLK1_PLK1_ST	Q9NS56	TOPORS	P53350	PLK1	S1032	R1030L	1030	Missense	proximal	-2	no	12.908	12.186	EPSD	TCGA;COSMIC	10.919	Down-regulation
Other_PLK_PLK1_PLK1_ST	Q9NS56	TOPORS	P53350	PLK1	S1032	S1032L	1032	Missense	central	0	yes	12.908	0.000	EPSD	TCGA;COSMIC	10.919	Loss
Other_PLK_PLK1_PLK1_ST	Q9NS56	TOPORS	P53350	PLK1	S1032	L1038V	1038	Missense	distal	6	no	12.908	12.977	EPSD	TCGA;COSMIC	10.919	Up-regulation
Other_PLK_PLK1_PLK1_ST	Q9NS56	TOPORS	P53350	PLK1	S1032	R1030W	1030	Missense	proximal	-2	no	12.908	6.250	EPSD	TCGA;COSMIC	10.919	Loss
Other_PLK_PLK1_PLK1_ST	Q9NS56	TOPORS	P53350	PLK1	S1035	S1032L	1032	Missense	distal	-3	no	10.632	11.406	EPSD	TCGA;COSMIC	10.919	Gain
Other_PLK_PLK1_PLK1_ST	Q9NS56	TOPORS	P53350	PLK1	S1035	L1038V	1038	Missense	distal	3	no	10.632	10.931	EPSD	TCGA;COSMIC	10.919	Gain
Other_PLK_PLK1_PLK1_ST	P35222	CTNNB1	P53350	PLK1	S29	G34R	34	Missense	distal	5	no	11.718	11.880	EPSD	TCGA;COSMIC	10.919	Up-regulation
Other_PLK_PLK1_PLK1_ST	P35222	CTNNB1	P53350	PLK1	S29	G34V	34	Missense	distal	5	no	11.718	11.364	EPSD	TCGA;COSMIC;CCLE	10.919	Down-regulation
Other_PLK_PLK1_PLK1_ST	P35222	CTNNB1	P53350	PLK1	S29	G34E	34	Missense	distal	5	no	11.718	11.243	EPSD	TCGA;COSMIC;GDSC;CCLE	10.919	Down-regulation
Other_PLK_PLK1_PLK1_ST	P35222	CTNNB1	P53350	PLK1	S29	S33F	33	Missense	distal	4	no	11.718	10.904	EPSD	TCGA;COSMIC;GDSC;CCLE	10.919	Loss
Other_PLK_PLK1_PLK1_ST	P35222	CTNNB1	P53350	PLK1	S29	D32H	32	Missense	distal	3	no	11.718	11.480	EPSD	TCGA;COSMIC	10.919	Down-regulation
Other_PLK_PLK1_PLK1_ST	P35222	CTNNB1	P53350	PLK1	S29	D32G	32	Missense	distal	3	no	11.718	11.475	EPSD	TCGA;COSMIC	10.919	Down-regulation
Other_PLK_PLK1_PLK1_ST	P35222	CTNNB1	P53350	PLK1	S29	S33A	33	Missense	distal	4	no	11.718	11.519	EPSD	TCGA;COSMIC	10.919	Down-regulation
Other_PLK_PLK1_PLK1_ST	P35222	CTNNB1	P53350	PLK1	S29	S33Y	33	Missense	distal	4	no	11.718	11.475	EPSD	TCGA;COSMIC;GDSC;CCLE	10.919	Down-regulation
Other_PLK_PLK1_PLK1_ST	P35222	CTNNB1	P53350	PLK1	S29	D32V	32	Missense	distal	3	no	11.718	11.624	EPSD	TCGA;COSMIC;CCLE	10.919	Down-regulation
Other_PLK_PLK1_PLK1_ST	P35222	CTNNB1	P53350	PLK1	S29	S33P	33	Missense	distal	4	no	11.718	11.396	EPSD	TCGA;COSMIC;CCLE	10.919	Down-regulation
Other_PLK_PLK1_PLK1_ST	P35222	CTNNB1	P53350	PLK1	S29	H36P	36	Missense	distal	7	no	11.718	11.759	EPSD	TCGA;COSMIC;CCLE	10.919	Up-regulation
Other_PLK_PLK1_PLK1_ST	P35222	CTNNB1	P53350	PLK1	S29	D32Y	32	Missense	distal	3	no	11.718	11.292	EPSD	TCGA;COSMIC;CCLE	10.919	Down-regulation
Other_PLK_PLK1_PLK1_ST	P35222	CTNNB1	P53350	PLK1	S29	I35S	35	Missense	distal	6	no	11.718	11.716	EPSD	TCGA;COSMIC	10.919	Down-regulation
Other_PLK_PLK1_PLK1_ST	P35222	CTNNB1	P53350	PLK1	S29	S33C	33	Missense	distal	4	no	11.718	11.191	EPSD	TCGA;COSMIC;GDSC;CCLE	10.919	Down-regulation
Other_PLK_PLK1_PLK1_ST	P35222	CTNNB1	P53350	PLK1	S29	D32N	32	Missense	distal	3	no	11.718	11.518	EPSD	TCGA;COSMIC;CCLE	10.919	Down-regulation
Other_PLK_PLK1_PLK1_ST	P35222	CTNNB1	P53350	PLK1	S29	S33T	33	Missense	distal	4	no	11.718	11.526	EPSD	TCGA;COSMIC	10.919	Down-regulation
Other_PLK_PLK1_PLK1_ST	P35222	CTNNB1	P53350	PLK1	S29	D32A	32	Missense	distal	3	no	11.718	11.296	EPSD	TCGA;COSMIC	10.919	Down-regulation
Other_PLK_PLK1_PLK1_ST	P35222	CTNNB1	P53350	PLK1	S33	G34R	34	Missense	proximal	1	no	11.011	8.910	EPSD	TCGA;COSMIC	10.919	Loss
Other_PLK_PLK1_PLK1_ST	P35222	CTNNB1	P53350	PLK1	S33	G34V	34	Missense	proximal	1	no	11.011	11.642	EPSD	TCGA;COSMIC;CCLE	10.919	Up-regulation
Other_PLK_PLK1_PLK1_ST	P35222	CTNNB1	P53350	PLK1	S33	G34E	34	Missense	proximal	1	no	11.011	10.765	EPSD	TCGA;COSMIC;GDSC;CCLE	10.919	Loss
Other_PLK_PLK1_PLK1_ST	P35222	CTNNB1	P53350	PLK1	S33	S37C	37	Missense	distal	4	no	11.011	10.484	EPSD	TCGA;COSMIC;GDSC;CCLE	10.919	Loss
Other_PLK_PLK1_PLK1_ST	P35222	CTNNB1	P53350	PLK1	S33	S37F	37	Missense	distal	4	no	11.011	10.197	EPSD	TCGA;COSMIC;GDSC;CCLE	10.919	Loss
Other_PLK_PLK1_PLK1_ST	P35222	CTNNB1	P53350	PLK1	S33	S33F	33	Missense	central	0	yes	11.011	0.000	EPSD	TCGA;COSMIC;GDSC;CCLE	10.919	Loss
Other_PLK_PLK1_PLK1_ST	P35222	CTNNB1	P53350	PLK1	S33	D32H	32	Missense	proximal	-1	no	11.011	10.279	EPSD	TCGA;COSMIC	10.919	Loss
Other_PLK_PLK1_PLK1_ST	P35222	CTNNB1	P53350	PLK1	S33	D32G	32	Missense	proximal	-1	no	11.011	8.421	EPSD	TCGA;COSMIC	10.919	Loss
Other_PLK_PLK1_PLK1_ST	P35222	CTNNB1	P53350	PLK1	S33	S33A	33	Missense	central	0	yes	11.011	0.000	EPSD	TCGA;COSMIC	10.919	Loss
Other_PLK_PLK1_PLK1_ST	P35222	CTNNB1	P53350	PLK1	S33	S33Y	33	Missense	central	0	yes	11.011	0.000	EPSD	TCGA;COSMIC;GDSC;CCLE	10.919	Loss
Other_PLK_PLK1_PLK1_ST	P35222	CTNNB1	P53350	PLK1	S33	D32V	32	Missense	proximal	-1	no	11.011	9.261	EPSD	TCGA;COSMIC;CCLE	10.919	Loss
Other_PLK_PLK1_PLK1_ST	P35222	CTNNB1	P53350	PLK1	S33	S33P	33	Missense	central	0	yes	11.011	0.000	EPSD	TCGA;COSMIC;CCLE	10.919	Loss
Other_PLK_PLK1_PLK1_ST	P35222	CTNNB1	P53350	PLK1	S33	H36P	36	Missense	distal	3	no	11.011	11.025	EPSD	TCGA;COSMIC;CCLE	10.919	Up-regulation
Other_PLK_PLK1_PLK1_ST	P35222	CTNNB1	P53350	PLK1	S33	D32Y	32	Missense	proximal	-1	no	11.011	10.554	EPSD	TCGA;COSMIC;CCLE	10.919	Loss
Other_PLK_PLK1_PLK1_ST	P35222	CTNNB1	P53350	PLK1	S33	I35S	35	Missense	proximal	2	no	11.011	10.590	EPSD	TCGA;COSMIC	10.919	Loss
Other_PLK_PLK1_PLK1_ST	P35222	CTNNB1	P53350	PLK1	S33	S37Y	37	Missense	distal	4	no	11.011	10.768	EPSD	TCGA;COSMIC	10.919	Loss
Other_PLK_PLK1_PLK1_ST	P35222	CTNNB1	P53350	PLK1	S33	S33C	33	Missense	central	0	yes	11.011	0.000	EPSD	TCGA;COSMIC;GDSC;CCLE	10.919	Loss
Other_PLK_PLK1_PLK1_ST	P35222	CTNNB1	P53350	PLK1	S33	S37A	37	Missense	distal	4	no	11.011	10.812	EPSD	TCGA;COSMIC;GDSC;CCLE	10.919	Loss
Other_PLK_PLK1_PLK1_ST	P35222	CTNNB1	P53350	PLK1	S33	D32N	32	Missense	proximal	-1	no	11.011	10.078	EPSD	TCGA;COSMIC;CCLE	10.919	Loss
Other_PLK_PLK1_PLK1_ST	P35222	CTNNB1	P53350	PLK1	S33	S37P	37	Missense	distal	4	no	11.011	10.689	EPSD	TCGA;COSMIC;GDSC;CCLE	10.919	Loss
Other_PLK_PLK1_PLK1_ST	P35222	CTNNB1	P53350	PLK1	S33	D32A	32	Missense	proximal	-1	no	11.011	9.751	EPSD	TCGA;COSMIC	10.919	Loss
Other_PLK_PLK1_PLK1_ST	P35222	CTNNB1	P53350	PLK1	T59	S60F	60	Missense	proximal	1	no	9.909	12.957	EPSD	TCGA;COSMIC	10.919	Gain
Other_PLK_PLK1_PLK1_ST	P35222	CTNNB1	P53350	PLK1	S60	S60F	60	Missense	central	0	yes	11.105	0.000	EPSD	TCGA;COSMIC	10.919	Loss
Other_PLK_PLK1_PLK1_ST	P35222	CTNNB1	P53350	PLK1	S60	E54D	54	Missense	distal	-6	no	11.105	10.902	EPSD	TCGA;COSMIC	10.919	Loss
Other_PLK_PLK1_PLK1_ST	P35222	CTNNB1	P53350	PLK1	S60	E55K	55	Missense	distal	-5	no	11.105	11.349	EPSD	TCGA;COSMIC	10.919	Up-regulation
Other_PLK_PLK1_PLK1_ST	P35222	CTNNB1	P53350	PLK1	S73	T75I	75	Missense	proximal	2	no	11.321	12.382	EPSD	TCGA;COSMIC	10.919	Up-regulation
Other_PLK_PLK1_PLK1_ST	P35222	CTNNB1	P53350	PLK1	S73	A80T	80	Missense	distal	7	no	11.321	11.281	EPSD	TCGA	10.919	Down-regulation
Other_PLK_PLK1_PLK1_ST	P35222	CTNNB1	P53350	PLK1	S129	V136A	136	Missense	distal	7	no	12.097	12.074	EPSD	TCGA;COSMIC	10.919	Down-regulation
Other_PLK_PLK1_PLK1_ST	P35222	CTNNB1	P53350	PLK1	S129	Q123H	123	Missense	distal	-6	no	12.097	12.109	EPSD	TCGA;COSMIC	10.919	Up-regulation
Other_PLK_PLK1_PLK1_ST	P35222	CTNNB1	P53350	PLK1	S129	R124C	124	Missense	distal	-5	no	12.097	11.431	EPSD	TCGA	10.919	Down-regulation
Other_PLK_PLK1_PLK1_ST	P35222	CTNNB1	P53350	PLK1	S250	I256M	256	Missense	distal	6	no	11.759	11.503	EPSD	TCGA;COSMIC	10.919	Down-regulation
Other_PLK_PLK1_PLK1_ST	P35222	CTNNB1	P53350	PLK1	S250	I256T	256	Missense	distal	6	no	11.759	12.034	EPSD	TCGA;COSMIC	10.919	Up-regulation
Other_PLK_PLK1_PLK1_ST	P35222	CTNNB1	P53350	PLK1	T679	F683Y	683	Missense	distal	4	no	11.192	11.763	EPSD	TCGA;COSMIC	10.919	Up-regulation
Other_PLK_PLK1_PLK1_ST	P35222	CTNNB1	P53350	PLK1	T679	S681F	681	Missense	proximal	2	no	11.192	10.641	EPSD	TCGA	10.919	Loss
Other_PLK_PLK1_PLK1_ST	P35222	CTNNB1	P53350	PLK1	S715	R717H	717	Missense	proximal	2	no	10.651	11.353	EPSD	TCGA;COSMIC	10.919	Gain
Other_PLK_PLK1_PLK1_ST	P35222	CTNNB1	P53350	PLK1	S715	P714L	714	Missense	proximal	-1	no	10.651	11.365	EPSD	TCGA;COSMIC	10.919	Gain
Other_PLK_PLK1_PLK1_ST	P35222	CTNNB1	P53350	PLK1	S718	R717H	717	Missense	proximal	-1	no	14.009	15.006	PhosphoSitePlus	TCGA;COSMIC	10.919	Up-regulation
Other_PLK_PLK1_PLK1_ST	P35222	CTNNB1	P53350	PLK1	S718	P714R	714	Missense	distal	-4	no	14.009	13.565	PhosphoSitePlus	TCGA;COSMIC	10.919	Down-regulation
Other_PLK_PLK1_PLK1_ST	P35222	CTNNB1	P53350	PLK1	S718	P714L	714	Missense	distal	-4	no	14.009	13.938	PhosphoSitePlus	TCGA;COSMIC	10.919	Down-regulation
Other_PLK_PLK1_PLK1_ST	O94901	SUN1	P53350	PLK1	S123	V116I	116	Missense	distal	-7	no	10.959	10.794	EPSD	TCGA;ICGC;COSMIC	10.919	Loss
Other_PLK_PLK1_PLK1_ST	O94901	SUN1	P53350	PLK1	S123	R130Q	130	Missense	distal	7	no	10.959	10.974	EPSD	TCGA;ICGC;COSMIC	10.919	Up-regulation
Other_PLK_PLK1_PLK1_ST	O94901	SUN1	P53350	PLK1	S138	P132S	132	Missense	distal	-6	no	14.201	14.825	PhosphoSitePlus	TCGA;ICGC	10.919	Up-regulation
Other_PLK_PLK1_PLK1_ST	O94901	SUN1	P53350	PLK1	S138	R141C	141	Missense	distal	3	no	14.201	14.261	PhosphoSitePlus	TCGA;ICGC;COSMIC	10.919	Up-regulation
Other_PLK_PLK1_PLK1_ST	O94901	SUN1	P53350	PLK1	S138	L135F	135	Missense	distal	-3	no	14.201	12.798	PhosphoSitePlus	TCGA;ICGC;COSMIC	10.919	Down-regulation
Other_PLK_PLK1_PLK1_ST	O94901	SUN1	P53350	PLK1	S138	R131W	131	Missense	distal	-7	no	14.201	14.787	PhosphoSitePlus	TCGA;ICGC	10.919	Up-regulation
Other_PLK_PLK1_PLK1_ST	O94901	SUN1	P53350	PLK1	T199	A200S	200	Missense	proximal	1	no	11.150	11.020	EPSD	TCGA;ICGC;COSMIC	10.919	Down-regulation
Other_PLK_PLK1_PLK1_ST	P06748	NPM1	P53350	PLK1	S4	D3Y	3	Missense	proximal	-1	no	11.886	11.429	PhosphoSitePlus	TCGA	10.919	Down-regulation
Other_PLK_PLK1_PLK1_ST	P06748	NPM1	P53350	PLK1	S4	S4L	4	Missense	central	0	yes	11.886	0.000	PhosphoSitePlus	TCGA;ICGC;COSMIC	10.919	Loss
Other_PLK_PLK1_PLK1_ST	P06748	NPM1	P53350	PLK1	S10	D3Y	3	Missense	distal	-7	no	11.004	10.742	EPSD	TCGA	10.919	Loss
Other_PLK_PLK1_PLK1_ST	P06748	NPM1	P53350	PLK1	S10	L12M	12	Missense	proximal	2	no	11.004	10.930	EPSD	TCGA;ICGC;COSMIC	10.919	Down-regulation
Other_PLK_PLK1_PLK1_ST	P06748	NPM1	P53350	PLK1	S10	S4L	4	Missense	distal	-6	no	11.004	10.670	EPSD	TCGA;ICGC;COSMIC	10.919	Loss
Other_PLK_PLK1_PLK1_ST	P06748	NPM1	P53350	PLK1	S70	K73Q	73	Missense	distal	3	no	11.260	11.358	EPSD	TCGA;ICGC;COSMIC	10.919	Up-regulation
Other_PLK_PLK1_PLK1_ST	P06748	NPM1	P53350	PLK1	S149	G147D	147	Missense	proximal	-2	no	9.993	13.315	EPSD	TCGA;ICGC;COSMIC	10.919	Gain
Other_PLK_PLK1_PLK1_ST	P06748	NPM1	P53350	PLK1	S214	P216S	216	Missense	proximal	2	no	10.660	12.137	EPSD	TCGA;ICGC;COSMIC	10.919	Gain
Other_PLK_PLK1_PLK1_ST	Q13158	FADD	P53350	PLK1	S18	E19K	19	Missense	proximal	1	no	11.156	10.706	EPSD	TCGA;ICGC;COSMIC	10.919	Loss
Other_PLK_PLK1_PLK1_ST	Q13158	FADD	P53350	PLK1	S18	S12W	12	Missense	distal	-6	no	11.156	10.252	EPSD	TCGA;ICGC;COSMIC	10.919	Loss
Other_PLK_PLK1_PLK1_ST	Q13158	FADD	P53350	PLK1	S18	F25L	25	Missense	distal	7	no	11.156	11.085	EPSD	TCGA;ICGC	10.919	Down-regulation
Other_PLK_PLK1_PLK1_ST	Q13158	FADD	P53350	PLK1	S47	G42R	42	Missense	distal	-5	no	10.899	11.184	EPSD	TCGA	10.919	Gain
Other_PLK_PLK1_PLK1_ST	Q13158	FADD	P53350	PLK1	S69	S69F	69	Missense	central	0	yes	11.094	0.000	EPSD	TCGA;ICGC;COSMIC	10.919	Loss
Other_PLK_PLK1_PLK1_ST	Q13158	FADD	P53350	PLK1	S69	D74Y	74	Missense	distal	5	no	11.094	10.788	EPSD	TCGA;ICGC;COSMIC	10.919	Loss
Other_PLK_PLK1_PLK1_ST	Q13158	FADD	P53350	PLK1	S69	R72H	72	Missense	distal	3	no	11.094	11.226	EPSD	TCGA;ICGC;COSMIC	10.919	Up-regulation
Other_PLK_PLK1_PLK1_ST	Q13158	FADD	P53350	PLK1	S190	P195L	195	Missense	distal	5	no	11.755	11.022	EPSD	TCGA;COSMIC	10.919	Down-regulation
Other_PLK_PLK1_PLK1_ST	Q13158	FADD	P53350	PLK1	S190	N188Y	188	Missense	proximal	-2	no	11.755	11.456	EPSD	TCGA;ICGC;COSMIC	10.919	Down-regulation
Other_PLK_PLK1_PLK1_ST	Q13158	FADD	P53350	PLK1	S194	P195L	195	Missense	proximal	1	no	13.059	13.904	PhosphoSitePlus	TCGA;COSMIC	10.919	Up-regulation
Other_PLK_PLK1_PLK1_ST	Q13158	FADD	P53350	PLK1	S194	N188Y	188	Missense	distal	-6	no	13.059	12.402	PhosphoSitePlus	TCGA;ICGC;COSMIC	10.919	Down-regulation
Other_PLK_PLK1_PLK1_ST	Q13158	FADD	P53350	PLK1	S197	P195L	195	Missense	proximal	-2	no	11.761	11.397	EPSD	TCGA;COSMIC	10.919	Down-regulation
Other_PLK_PLK1_PLK1_ST	Q13158	FADD	P53350	PLK1	S203	S205Y	205	Missense	proximal	2	no	12.239	11.871	EPSD	TCGA;ICGC;COSMIC	10.919	Down-regulation
Other_PLK_PLK1_PLK1_ST	Q13158	FADD	P53350	PLK1	S203	A207V	207	Missense	distal	4	no	12.239	11.975	EPSD	TCGA;ICGC;COSMIC;GDSC	10.919	Down-regulation
Other_PLK_PLK1_PLK1_ST	P38398	BRCA1	P53350	PLK1	S114	N113K	113	Missense	proximal	-1	no	12.949	12.515	EPSD	TCGA;ICGC;COSMIC	10.919	Down-regulation
Other_PLK_PLK1_PLK1_ST	P38398	BRCA1	P53350	PLK1	S123	G129C	129	Missense	distal	6	no	14.179	13.451	EPSD	TCGA;ICGC	10.919	Down-regulation
Other_PLK_PLK1_PLK1_ST	P38398	BRCA1	P53350	PLK1	S187	S184C	184	Missense	distal	-3	no	11.737	11.773	EPSD	TCGA;ICGC;COSMIC	10.919	Up-regulation
Other_PLK_PLK1_PLK1_ST	P38398	BRCA1	P53350	PLK1	S187	E181D	181	Missense	distal	-6	no	11.737	11.534	EPSD	TCGA;ICGC;COSMIC	10.919	Down-regulation
Other_PLK_PLK1_PLK1_ST	P38398	BRCA1	P53350	PLK1	T190	S184C	184	Missense	distal	-6	no	11.651	10.448	EPSD	TCGA;ICGC;COSMIC	10.919	Loss
Other_PLK_PLK1_PLK1_ST	P38398	BRCA1	P53350	PLK1	T208	T212A	212	Missense	distal	4	no	11.967	11.960	EPSD	TCGA;ICGC	10.919	Down-regulation
Other_PLK_PLK1_PLK1_ST	P38398	BRCA1	P53350	PLK1	S398	E402K	402	Missense	distal	4	no	13.579	13.205	EPSD	TCGA;COSMIC	10.919	Down-regulation
Other_PLK_PLK1_PLK1_ST	P38398	BRCA1	P53350	PLK1	S405	E402K	402	Missense	distal	-3	no	10.794	11.334	EPSD	TCGA;COSMIC	10.919	Gain
Other_PLK_PLK1_PLK1_ST	P38398	BRCA1	P53350	PLK1	S449	R446T	446	Missense	distal	-3	no	11.067	10.612	EPSD	TCGA;COSMIC	10.919	Loss
Other_PLK_PLK1_PLK1_ST	P38398	BRCA1	P53350	PLK1	S603	P606L	606	Missense	distal	3	no	12.032	11.864	EPSD	TCGA;COSMIC	10.919	Down-regulation
Other_PLK_PLK1_PLK1_ST	P38398	BRCA1	P53350	PLK1	S603	R610M	610	Missense	distal	7	no	12.032	12.084	EPSD	TCGA;COSMIC	10.919	Up-regulation
Other_PLK_PLK1_PLK1_ST	P38398	BRCA1	P53350	PLK1	S603	E597K	597	Missense	distal	-6	no	12.032	11.458	EPSD	TCGA;COSMIC	10.919	Down-regulation
Other_PLK_PLK1_PLK1_ST	P38398	BRCA1	P53350	PLK1	S763	E765Q	765	Missense	proximal	2	no	12.964	13.152	EPSD	TCGA;COSMIC	10.919	Up-regulation
Other_PLK_PLK1_PLK1_ST	P38398	BRCA1	P53350	PLK1	S767	E765Q	765	Missense	proximal	-2	no	12.355	9.696	EPSD	TCGA;COSMIC	10.919	Loss
Other_PLK_PLK1_PLK1_ST	P38398	BRCA1	P53350	PLK1	S868	P871S	871	Missense	distal	3	no	12.088	12.067	EPSD	TCGA;COSMIC	10.919	Down-regulation
Other_PLK_PLK1_PLK1_ST	P38398	BRCA1	P53350	PLK1	S868	S873L	873	Missense	distal	5	no	12.088	11.742	EPSD	TCGA;COSMIC	10.919	Down-regulation
Other_PLK_PLK1_PLK1_ST	P38398	BRCA1	P53350	PLK1	S868	P875S	875	Missense	distal	7	no	12.088	12.061	EPSD	TCGA;COSMIC	10.919	Down-regulation
Other_PLK_PLK1_PLK1_ST	P38398	BRCA1	P53350	PLK1	S868	R866C	866	Missense	proximal	-2	no	12.088	9.914	EPSD	TCGA;COSMIC	10.919	Loss
Other_PLK_PLK1_PLK1_ST	P38398	BRCA1	P53350	PLK1	T963	Q957E	957	Missense	distal	-6	no	12.354	12.473	EPSD	TCGA;COSMIC	10.919	Up-regulation
Other_PLK_PLK1_PLK1_ST	P38398	BRCA1	P53350	PLK1	T963	E962A	962	Missense	proximal	-1	no	12.354	11.890	EPSD	TCGA;COSMIC	10.919	Down-regulation
Other_PLK_PLK1_PLK1_ST	P38398	BRCA1	P53350	PLK1	S988	P982L	982	Missense	distal	-6	no	11.154	11.443	EPSD	TCGA;COSMIC	10.919	Up-regulation
Other_PLK_PLK1_PLK1_ST	P38398	BRCA1	P53350	PLK1	S988	P985L	985	Missense	distal	-3	no	11.154	12.346	EPSD	TCGA;COSMIC	10.919	Up-regulation
Other_PLK_PLK1_PLK1_ST	P38398	BRCA1	P53350	PLK1	S988	K991Q	991	Missense	distal	3	no	11.154	11.252	EPSD	TCGA;COSMIC	10.919	Up-regulation
Other_PLK_PLK1_PLK1_ST	P38398	BRCA1	P53350	PLK1	S1007	E1013Q	1013	Missense	distal	6	no	13.576	13.436	EPSD	TCGA	10.919	Down-regulation
Other_PLK_PLK1_PLK1_ST	P38398	BRCA1	P53350	PLK1	S1007	N1002K	1002	Missense	distal	-5	no	13.576	13.775	EPSD	TCGA	10.919	Up-regulation
Other_PLK_PLK1_PLK1_ST	P38398	BRCA1	P53350	PLK1	S1266	L1261V	1261	Missense	distal	-5	no	12.154	11.701	EPSD	TCGA;COSMIC	10.919	Down-regulation
Other_PLK_PLK1_PLK1_ST	Q9BQQ3	GORASP1	P53350	PLK1	S189	A182T	182	Missense	distal	-7	no	12.383	12.728	PhosphoSitePlus	TCGA;ICGC;COSMIC;GDSC;CCLE	10.919	Up-regulation
Other_PLK_PLK1_PLK1_ST	Q9BQQ3	GORASP1	P53350	PLK1	S189	A183T	183	Missense	distal	-6	no	12.383	12.316	PhosphoSitePlus	TCGA;ICGC	10.919	Down-regulation
Other_PLK_PLK1_PLK1_ST	P51587	BRCA2	P53350	PLK1	S158	S158P	158	Missense	central	0	yes	12.741	0.000	EPSD	TCGA;ICGC;COSMIC	10.919	Loss
Other_PLK_PLK1_PLK1_ST	P51587	BRCA2	P53350	PLK1	S158	C161S	161	Missense	distal	3	no	12.741	12.805	EPSD	TCGA;ICGC	10.919	Up-regulation
Other_PLK_PLK1_PLK1_ST	P51587	BRCA2	P53350	PLK1	S158	R155I	155	Missense	distal	-3	no	12.741	12.308	EPSD	TCGA;ICGC;COSMIC	10.919	Down-regulation
Other_PLK_PLK1_PLK1_ST	P51587	BRCA2	P53350	PLK1	S193	M192T	192	Missense	proximal	-1	no	15.882	15.063	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	10.919	Down-regulation
Other_PLK_PLK1_PLK1_ST	P51587	BRCA2	P53350	PLK1	S193	D189H	189	Missense	distal	-4	no	15.882	15.810	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	10.919	Down-regulation
Other_PLK_PLK1_PLK1_ST	P51587	BRCA2	P53350	PLK1	S193	A186S	186	Missense	distal	-7	no	15.882	16.235	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	10.919	Up-regulation
Other_PLK_PLK1_PLK1_ST	P51587	BRCA2	P53350	PLK1	S193	S196I	196	Missense	distal	3	no	15.882	15.911	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	10.919	Up-regulation
Other_PLK_PLK1_PLK1_ST	P51587	BRCA2	P53350	PLK1	S193	D191N	191	Missense	proximal	-2	no	15.882	14.639	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	10.919	Down-regulation
Other_PLK_PLK1_PLK1_ST	P51587	BRCA2	P53350	PLK1	T203	S205R	205	Missense	proximal	2	no	12.549	11.821	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	10.919	Down-regulation
Other_PLK_PLK1_PLK1_ST	P51587	BRCA2	P53350	PLK1	T203	S206C	206	Missense	distal	3	no	12.549	12.484	EPSD;PhosphoSitePlus	TCGA	10.919	Down-regulation
Other_PLK_PLK1_PLK1_ST	P51587	BRCA2	P53350	PLK1	T203	S196I	196	Missense	distal	-7	no	12.549	12.087	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	10.919	Down-regulation
Other_PLK_PLK1_PLK1_ST	P51587	BRCA2	P53350	PLK1	T203	P202S	202	Missense	proximal	-1	no	12.549	13.723	EPSD;PhosphoSitePlus	TCGA;ICGC	10.919	Up-regulation
Other_PLK_PLK1_PLK1_ST	P51587	BRCA2	P53350	PLK1	T203	P201S	201	Missense	proximal	-2	no	12.549	13.133	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	10.919	Up-regulation
Other_PLK_PLK1_PLK1_ST	P51587	BRCA2	P53350	PLK1	S273	C279Y	279	Missense	distal	6	no	11.890	12.295	EPSD	TCGA;ICGC	10.919	Up-regulation
Other_PLK_PLK1_PLK1_ST	P51587	BRCA2	P53350	PLK1	S273	S278N	278	Missense	distal	5	no	11.890	11.286	EPSD	TCGA;ICGC	10.919	Down-regulation
Other_PLK_PLK1_PLK1_ST	P51587	BRCA2	P53350	PLK1	S445	E443D	443	Missense	proximal	-2	no	10.802	11.196	EPSD	TCGA;ICGC;COSMIC	10.919	Gain
Other_PLK_PLK1_PLK1_ST	P51587	BRCA2	P53350	PLK1	S497	G500V	500	Missense	distal	3	no	11.358	11.507	EPSD	TCGA;ICGC;COSMIC	10.919	Up-regulation
Other_PLK_PLK1_PLK1_ST	P51587	BRCA2	P53350	PLK1	S497	S497L	497	Missense	central	0	yes	11.358	0.000	EPSD	TCGA;ICGC;COSMIC	10.919	Loss
Other_PLK_PLK1_PLK1_ST	P51587	BRCA2	P53350	PLK1	S497	P493L	493	Missense	distal	-4	no	11.358	11.286	EPSD	TCGA;ICGC;COSMIC	10.919	Down-regulation
Other_PLK_PLK1_PLK1_ST	P51587	BRCA2	P53350	PLK1	S497	V494A	494	Missense	distal	-3	no	11.358	11.757	EPSD	TCGA;ICGC;COSMIC	10.919	Up-regulation
Other_PLK_PLK1_PLK1_ST	P51587	BRCA2	P53350	PLK1	S519	D526N	526	Missense	distal	7	no	12.991	13.073	EPSD	TCGA;ICGC;COSMIC	10.919	Up-regulation
Other_PLK_PLK1_PLK1_ST	P51587	BRCA2	P53350	PLK1	S519	N517S	517	Missense	proximal	-2	no	12.991	11.581	EPSD	TCGA;ICGC;COSMIC	10.919	Down-regulation
Other_PLK_PLK1_PLK1_ST	P51587	BRCA2	P53350	PLK1	S519	E514G	514	Missense	distal	-5	no	12.991	13.487	EPSD	TCGA;ICGC;COSMIC	10.919	Up-regulation
Other_PLK_PLK1_PLK1_ST	P51587	BRCA2	P53350	PLK1	S519	A518V	518	Missense	proximal	-1	no	12.991	12.501	EPSD	TCGA;ICGC;COSMIC	10.919	Down-regulation
Other_PLK_PLK1_PLK1_ST	P51587	BRCA2	P53350	PLK1	S642	Q649H	649	Missense	distal	7	no	11.371	11.327	EPSD	TCGA;ICGC;COSMIC	10.919	Down-regulation
Other_PLK_PLK1_PLK1_ST	P51587	BRCA2	P53350	PLK1	S642	S641Y	641	Missense	proximal	-1	no	11.371	11.707	EPSD	TCGA;ICGC;COSMIC	10.919	Up-regulation
Other_PLK_PLK1_PLK1_ST	P51587	BRCA2	P53350	PLK1	S642	R645I	645	Missense	distal	3	no	11.371	11.524	EPSD	TCGA;ICGC;COSMIC	10.919	Up-regulation
Other_PLK_PLK1_PLK1_ST	P51587	BRCA2	P53350	PLK1	S646	R645I	645	Missense	proximal	-1	no	10.124	11.078	EPSD	TCGA;ICGC;COSMIC	10.919	Gain
Other_PLK_PLK1_PLK1_ST	P51587	BRCA2	P53350	PLK1	S648	Q649H	649	Missense	proximal	1	no	10.931	10.350	EPSD	TCGA;ICGC;COSMIC	10.919	Loss
Other_PLK_PLK1_PLK1_ST	P51587	BRCA2	P53350	PLK1	S648	S641Y	641	Missense	distal	-7	no	10.931	10.319	EPSD	TCGA;ICGC;COSMIC	10.919	Loss
Other_PLK_PLK1_PLK1_ST	P51587	BRCA2	P53350	PLK1	S648	R645I	645	Missense	distal	-3	no	10.931	10.499	EPSD	TCGA;ICGC;COSMIC	10.919	Loss
Other_PLK_PLK1_PLK1_ST	P51587	BRCA2	P53350	PLK1	S648	P655T	655	Missense	distal	7	no	10.931	10.889	EPSD	TCGA;ICGC;COSMIC	10.919	Loss
Other_PLK_PLK1_PLK1_ST	P51587	BRCA2	P53350	PLK1	S652	Q649H	649	Missense	distal	-3	no	12.192	12.195	EPSD	TCGA;ICGC;COSMIC	10.919	Up-regulation
Other_PLK_PLK1_PLK1_ST	P51587	BRCA2	P53350	PLK1	S652	R645I	645	Missense	distal	-7	no	12.192	12.227	EPSD	TCGA;ICGC;COSMIC	10.919	Up-regulation
Other_PLK_PLK1_PLK1_ST	P51587	BRCA2	P53350	PLK1	S652	P655T	655	Missense	distal	3	no	12.192	12.034	EPSD	TCGA;ICGC;COSMIC	10.919	Down-regulation
Other_PLK_PLK1_PLK1_ST	P51587	BRCA2	P53350	PLK1	T656	Q649H	649	Missense	distal	-7	no	12.455	12.435	EPSD	TCGA;ICGC;COSMIC	10.919	Down-regulation
Other_PLK_PLK1_PLK1_ST	P51587	BRCA2	P53350	PLK1	T656	P655T	655	Missense	proximal	-1	no	12.455	12.882	EPSD	TCGA;ICGC;COSMIC	10.919	Up-regulation
Other_PLK_PLK1_PLK1_ST	P51587	BRCA2	P53350	PLK1	S683	D687H	687	Missense	distal	4	no	11.401	10.877	EPSD	TCGA;ICGC;COSMIC	10.919	Loss
Other_PLK_PLK1_PLK1_ST	P51587	BRCA2	P53350	PLK1	T768	A766T	766	Missense	proximal	-2	no	14.092	13.473	EPSD	TCGA;ICGC;COSMIC	10.919	Down-regulation
Other_PLK_PLK1_PLK1_ST	P51587	BRCA2	P53350	PLK1	T768	E764K	764	Missense	distal	-4	no	14.092	13.709	EPSD	TCGA;ICGC;COSMIC	10.919	Down-regulation
Other_PLK_PLK1_PLK1_ST	P51587	BRCA2	P53350	PLK1	T768	S767N	767	Missense	proximal	-1	no	14.092	13.951	EPSD	TCGA;ICGC	10.919	Down-regulation
Other_PLK_PLK1_PLK1_ST	P51587	BRCA2	P53350	PLK1	S976	S973L	973	Missense	distal	-3	no	11.705	12.479	EPSD	TCGA;ICGC;COSMIC	10.919	Up-regulation
Other_PLK_PLK1_PLK1_ST	P51587	BRCA2	P53350	PLK1	S976	N978S	978	Missense	proximal	2	no	11.705	11.491	EPSD	TCGA;ICGC;COSMIC	10.919	Down-regulation
Other_PLK_PLK1_PLK1_ST	P51587	BRCA2	P53350	PLK1	S976	D980N	980	Missense	distal	4	no	11.705	11.466	EPSD	TCGA;ICGC;COSMIC	10.919	Down-regulation
Other_PLK_PLK1_PLK1_ST	P51587	BRCA2	P53350	PLK1	T1141	I1136M	1136	Missense	distal	-5	no	11.419	11.115	EPSD	TCGA;ICGC;COSMIC	10.919	Down-regulation
Other_PLK_PLK1_PLK1_ST	P51587	BRCA2	P53350	PLK1	T1141	K1139N	1139	Missense	proximal	-2	no	11.419	13.448	EPSD	TCGA;ICGC;COSMIC	10.919	Up-regulation
Other_PLK_PLK1_PLK1_ST	P51587	BRCA2	P53350	PLK1	S1331	H1332D	1332	Missense	proximal	1	no	10.242	10.944	EPSD	TCGA;ICGC;COSMIC	10.919	Gain
Other_PLK_PLK1_PLK1_ST	P51587	BRCA2	P53350	PLK1	S1339	G1338D	1338	Missense	proximal	-1	no	9.553	12.143	EPSD	TCGA;ICGC;COSMIC	10.919	Gain
Other_PLK_PLK1_PLK1_ST	P51587	BRCA2	P53350	PLK1	S1770	G1771C	1771	Missense	proximal	1	no	11.341	10.638	EPSD	TCGA;ICGC;COSMIC	10.919	Loss
Other_PLK_PLK1_PLK1_ST	P51587	BRCA2	P53350	PLK1	S1770	I1772S	1772	Missense	proximal	2	no	11.341	10.919	EPSD	TCGA;ICGC;COSMIC	10.919	Down-regulation
Other_PLK_PLK1_PLK1_ST	P51587	BRCA2	P53350	PLK1	S1786	S1792F	1792	Missense	distal	6	no	16.155	15.579	EPSD	TCGA;ICGC;COSMIC	10.919	Down-regulation
Other_PLK_PLK1_PLK1_ST	P51587	BRCA2	P53350	PLK1	S1786	T1785I	1785	Missense	proximal	-1	no	16.155	16.919	EPSD	TCGA;ICGC;COSMIC	10.919	Up-regulation
Other_PLK_PLK1_PLK1_ST	P51587	BRCA2	P53350	PLK1	S1869	E1876K	1876	Missense	distal	7	no	11.617	11.690	EPSD	TCGA;ICGC;COSMIC;GDSC;CCLE	10.919	Up-regulation
Other_PLK_PLK1_PLK1_ST	P51587	BRCA2	P53350	PLK1	S1869	K1863N	1863	Missense	distal	-6	no	11.617	11.875	EPSD	TCGA;ICGC;COSMIC	10.919	Up-regulation
Other_PLK_PLK1_PLK1_ST	P51587	BRCA2	P53350	PLK1	S1951	D1956G	1956	Missense	distal	5	no	12.018	12.051	EPSD	TCGA;ICGC	10.919	Up-regulation
Other_PLK_PLK1_PLK1_ST	P51587	BRCA2	P53350	PLK1	S1955	S1961G	1961	Missense	distal	6	no	12.341	12.136	EPSD	TCGA;ICGC;COSMIC	10.919	Down-regulation
Other_PLK_PLK1_PLK1_ST	P51587	BRCA2	P53350	PLK1	S1955	D1956G	1956	Missense	proximal	1	no	12.341	12.343	EPSD	TCGA;ICGC	10.919	Up-regulation
Other_PLK_PLK1_PLK1_ST	P51587	BRCA2	P53350	PLK1	S2072	H2074D	2074	Missense	proximal	2	no	12.906	12.930	EPSD	TCGA;ICGC;COSMIC	10.919	Up-regulation
Other_PLK_PLK1_PLK1_ST	P51587	BRCA2	P53350	PLK1	S2072	V2079M	2079	Missense	distal	7	no	12.906	12.926	EPSD	TCGA;ICGC	10.919	Up-regulation
Other_PLK_PLK1_PLK1_ST	P51587	BRCA2	P53350	PLK1	S2072	S2067F	2067	Missense	distal	-5	no	12.906	12.645	EPSD	TCGA;ICGC;COSMIC	10.919	Down-regulation
Other_PLK_PLK1_PLK1_ST	P51587	BRCA2	P53350	PLK1	S2091	T2097M	2097	Missense	distal	6	no	12.331	11.801	EPSD	TCGA;ICGC;COSMIC	10.919	Down-regulation
Other_PLK_PLK1_PLK1_ST	P51587	BRCA2	P53350	PLK1	S2091	S2098T	2098	Missense	distal	7	no	12.331	12.316	EPSD	TCGA;ICGC;COSMIC	10.919	Down-regulation
Other_PLK_PLK1_PLK1_ST	P51587	BRCA2	P53350	PLK1	S2695	S2695L	2695	Missense	central	0	yes	10.982	0.000	EPSD	TCGA;ICGC;COSMIC	10.919	Loss
Other_PLK_PLK1_PLK1_ST	P51587	BRCA2	P53350	PLK1	S2697	S2695L	2695	Missense	proximal	-2	no	11.231	10.283	EPSD	TCGA;ICGC;COSMIC	10.919	Loss
Other_PLK_PLK1_PLK1_ST	P51587	BRCA2	P53350	PLK1	S2697	S2704F	2704	Missense	distal	7	no	11.231	11.300	EPSD	TCGA;ICGC;COSMIC	10.919	Up-regulation
Other_PLK_PLK1_PLK1_ST	P51587	BRCA2	P53350	PLK1	S2701	N2706S	2706	Missense	distal	5	no	12.697	13.301	EPSD	TCGA;ICGC	10.919	Up-regulation
Other_PLK_PLK1_PLK1_ST	P51587	BRCA2	P53350	PLK1	S2701	S2695L	2695	Missense	distal	-6	no	12.697	12.363	EPSD	TCGA;ICGC;COSMIC	10.919	Down-regulation
Other_PLK_PLK1_PLK1_ST	P51587	BRCA2	P53350	PLK1	S2701	S2704F	2704	Missense	distal	3	no	12.697	12.757	EPSD	TCGA;ICGC;COSMIC	10.919	Up-regulation
Other_PLK_PLK1_PLK1_ST	P51587	BRCA2	P53350	PLK1	T3310	C3304S	3304	Missense	distal	-6	no	10.203	11.406	EPSD	TCGA;ICGC;COSMIC	10.919	Gain
Other_PLK_PLK1_PLK1_ST	P51587	BRCA2	P53350	PLK1	S3397	T3401M	3401	Missense	distal	4	no	15.307	14.551	EPSD	TCGA;ICGC;COSMIC	10.919	Down-regulation
Other_PLK_PLK1_PLK1_ST	P51587	BRCA2	P53350	PLK1	S3397	E3393Q	3393	Missense	distal	-4	no	15.307	15.039	EPSD	TCGA;ICGC;COSMIC	10.919	Down-regulation
Other_PLK_PLK1_PLK1_ST	P51587	BRCA2	P53350	PLK1	S3397	E3403Q	3403	Missense	distal	6	no	15.307	15.167	EPSD	TCGA;ICGC;COSMIC	10.919	Down-regulation
Other_PLK_PLK1_PLK1_ST	P51587	BRCA2	P53350	PLK1	S3397	Q3398H	3398	Missense	proximal	1	no	15.307	14.725	EPSD	TCGA;ICGC;COSMIC	10.919	Down-regulation
Other_PLK_PLK1_PLK1_ST	P51587	BRCA2	P53350	PLK1	S3397	S3396R	3396	Missense	proximal	-1	no	15.307	14.371	EPSD	TCGA;ICGC;COSMIC	10.919	Down-regulation
Other_PLK_PLK1_PLK1_ST	P51587	BRCA2	P53350	PLK1	S3397	Q3398R	3398	Missense	proximal	1	no	15.307	13.329	EPSD	TCGA	10.919	Down-regulation
Other_PLK_PLK1_PLK1_ST	Q38SD2	LRRK1	P53350	PLK1	S1246	G1249D	1249	Missense	distal	3	no	10.899	11.142	EPSD	TCGA;COSMIC	10.919	Gain
Other_PLK_PLK1_PLK1_ST	Q38SD2	LRRK1	P53350	PLK1	S1302	R1305Q	1305	Missense	distal	3	no	11.509	11.705	EPSD	TCGA;COSMIC	10.919	Up-regulation
Other_PLK_PLK1_PLK1_ST	Q38SD2	LRRK1	P53350	PLK1	S1302	R1305W	1305	Missense	distal	3	no	11.509	11.280	EPSD	TCGA;COSMIC	10.919	Down-regulation
Other_PLK_PLK1_PLK1_ST	Q38SD2	LRRK1	P53350	PLK1	S1302	E1307A	1307	Missense	distal	5	no	11.509	12.367	EPSD	TCGA;COSMIC	10.919	Up-regulation
Other_PLK_PLK1_PLK1_ST	Q38SD2	LRRK1	P53350	PLK1	S1302	A1308V	1308	Missense	distal	6	no	11.509	11.334	EPSD	TCGA;COSMIC	10.919	Down-regulation
Other_PLK_PLK1_PLK1_ST	Q38SD2	LRRK1	P53350	PLK1	S1817	S1812F	1812	Missense	distal	-5	no	13.695	13.434	PhosphoSitePlus	TCGA;COSMIC	10.919	Down-regulation
Other_PLK_PLK1_PLK1_ST	Q38SD2	LRRK1	P53350	PLK1	S1817	D1811N	1811	Missense	distal	-6	no	13.695	13.582	PhosphoSitePlus	TCGA;COSMIC	10.919	Down-regulation
Other_PLK_PLK1_PLK1_ST	Q38SD2	LRRK1	P53350	PLK1	S1817	M1819V	1819	Missense	proximal	2	no	13.695	13.901	PhosphoSitePlus	TCGA;COSMIC	10.919	Up-regulation
Other_PLK_PLK1_PLK1_ST	Q9UBB4	ATXN10	P53350	PLK1	S77	N73H	73	Missense	distal	-4	no	12.314	12.183	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	10.919	Down-regulation
Other_PLK_PLK1_PLK1_ST	Q9UBB4	ATXN10	P53350	PLK1	S364	F370L	370	Missense	distal	6	no	12.850	13.466	EPSD	TCGA;COSMIC	10.919	Up-regulation
Other_PLK_PLK1_PLK1_ST	Q9UBB4	ATXN10	P53350	PLK1	T426	R423Q	423	Missense	distal	-3	no	11.561	10.886	EPSD	TCGA;COSMIC	10.919	Loss
Other_PLK_PLK1_PLK1_ST	Q9UBB4	ATXN10	P53350	PLK1	T426	L425F	425	Missense	proximal	-1	no	11.561	11.482	EPSD	TCGA;COSMIC	10.919	Down-regulation
Other_PLK_PLK1_PLK1_ST	Q9UBB4	ATXN10	P53350	PLK1	S430	R423Q	423	Missense	distal	-7	no	10.958	11.358	EPSD	TCGA;COSMIC	10.919	Up-regulation
Other_PLK_PLK1_PLK1_ST	Q9UBB4	ATXN10	P53350	PLK1	S430	L425F	425	Missense	distal	-5	no	10.958	10.033	EPSD	TCGA;COSMIC	10.919	Loss
Other_PLK_PLK1_PLK1_ST	Q9UBB4	ATXN10	P53350	PLK1	S430	D434N	434	Missense	distal	4	no	10.958	10.719	EPSD	TCGA;COSMIC	10.919	Loss
Other_PLK_PLK1_PLK1_ST	Q9H0H5	RACGAP1	P53350	PLK1	S66	R65Q	65	Missense	proximal	-1	no	12.638	13.242	EPSD	TCGA;ICGC;COSMIC	10.919	Up-regulation
Other_PLK_PLK1_PLK1_ST	Q9H0H5	RACGAP1	P53350	PLK1	S112	E119K	119	Missense	distal	7	no	12.534	12.607	EPSD	TCGA;ICGC;COSMIC	10.919	Up-regulation
Other_PLK_PLK1_PLK1_ST	Q9H0H5	RACGAP1	P53350	PLK1	S112	E105D	105	Missense	distal	-7	no	12.534	12.245	EPSD	TCGA;ICGC;COSMIC	10.919	Down-regulation
Other_PLK_PLK1_PLK1_ST	Q9H0H5	RACGAP1	P53350	PLK1	S149	S151Y	151	Missense	proximal	2	no	12.161	11.794	EPSD	TCGA;ICGC;COSMIC	10.919	Down-regulation
Other_PLK_PLK1_PLK1_ST	Q9H0H5	RACGAP1	P53350	PLK1	S149	I156V	156	Missense	distal	7	no	12.161	12.178	EPSD	TCGA	10.919	Up-regulation
Other_PLK_PLK1_PLK1_ST	Q9H0H5	RACGAP1	P53350	PLK1	S157	S151Y	151	Missense	distal	-6	no	16.092	15.238	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	10.919	Down-regulation
Other_PLK_PLK1_PLK1_ST	Q9H0H5	RACGAP1	P53350	PLK1	S157	I156V	156	Missense	proximal	-1	no	16.092	15.118	EPSD;PhosphoSitePlus	TCGA	10.919	Down-regulation
Other_PLK_PLK1_PLK1_ST	Q9H0H5	RACGAP1	P53350	PLK1	S164	D168N	168	Missense	distal	4	no	15.296	15.057	EPSD;PhosphoSitePlus	TCGA;ICGC	10.919	Down-regulation
Other_PLK_PLK1_PLK1_ST	Q9H0H5	RACGAP1	P53350	PLK1	S170	T174P	174	Missense	distal	4	no	17.385	17.256	PhosphoSitePlus;EPSD	TCGA;ICGC	10.919	Down-regulation
Other_PLK_PLK1_PLK1_ST	Q9H0H5	RACGAP1	P53350	PLK1	S170	D168N	168	Missense	proximal	-2	no	17.385	16.143	PhosphoSitePlus;EPSD	TCGA;ICGC	10.919	Down-regulation
Other_PLK_PLK1_PLK1_ST	Q9H0H5	RACGAP1	P53350	PLK1	S214	Q210H	210	Missense	distal	-4	no	11.094	11.107	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	10.919	Up-regulation
Other_PLK_PLK1_PLK1_ST	Q9H0H5	RACGAP1	P53350	PLK1	S559	S563L	563	Missense	distal	4	no	11.296	10.684	EPSD	TCGA;ICGC;COSMIC	10.919	Loss
Other_PLK_PLK1_PLK1_ST	Q9H0H5	RACGAP1	P53350	PLK1	S559	L553R	553	Missense	distal	-6	no	11.296	11.183	EPSD	TCGA;ICGC;COSMIC	10.919	Down-regulation
Other_PLK_PLK1_PLK1_ST	Q9H0H5	RACGAP1	P53350	PLK1	S573	P577S	577	Missense	distal	4	no	11.287	11.608	EPSD	TCGA;ICGC;COSMIC	10.919	Up-regulation
Other_PLK_PLK1_PLK1_ST	Q9H0H5	RACGAP1	P53350	PLK1	S593	R597K	597	Missense	distal	4	no	11.836	12.395	EPSD	TCGA;ICGC	10.919	Up-regulation
Other_PLK_PLK1_PLK1_ST	Q9H0H5	RACGAP1	P53350	PLK1	T606	S613T	613	Missense	distal	7	no	11.098	11.083	EPSD	TCGA;ICGC;COSMIC	10.919	Down-regulation
Other_PLK_PLK1_PLK1_ST	Q9H0H5	RACGAP1	P53350	PLK1	T606	P607L	607	Missense	proximal	1	no	11.098	11.944	EPSD	TCGA;ICGC;COSMIC	10.919	Up-regulation
Other_PLK_PLK1_PLK1_ST	Q9H0H5	RACGAP1	P53350	PLK1	T606	S613N	613	Missense	distal	7	no	11.098	11.154	EPSD	TCGA;ICGC;COSMIC	10.919	Up-regulation
Other_PLK_PLK1_PLK1_ST	Q9H0H5	RACGAP1	P53350	PLK1	S613	P607L	607	Missense	distal	-6	no	11.889	12.178	EPSD	TCGA;ICGC;COSMIC	10.919	Up-regulation
Other_PLK_PLK1_PLK1_ST	Q9H0H5	RACGAP1	P53350	PLK1	S613	S613N	613	Missense	central	0	yes	11.889	0.000	EPSD	TCGA;ICGC;COSMIC	10.919	Loss
Other_PLK_PLK1_PLK1_ST	O95251	KAT7	P53350	PLK1	S11	G9D	9	Missense	proximal	-2	no	8.740	12.062	EPSD	TCGA;ICGC	10.919	Gain
Other_PLK_PLK1_PLK1_ST	O95251	KAT7	P53350	PLK1	S18	D17H	17	Missense	proximal	-1	no	14.690	13.958	EPSD	TCGA;ICGC;COSMIC	10.919	Down-regulation
Other_PLK_PLK1_PLK1_ST	O95251	KAT7	P53350	PLK1	S18	S18F	18	Missense	central	0	yes	14.690	0.000	EPSD	TCGA;ICGC;COSMIC	10.919	Loss
Other_PLK_PLK1_PLK1_ST	O95251	KAT7	P53350	PLK1	S18	D17Y	17	Missense	proximal	-1	no	14.690	14.233	EPSD	TCGA;ICGC	10.919	Down-regulation
Other_PLK_PLK1_PLK1_ST	O95251	KAT7	P53350	PLK1	S18	L24F	24	Missense	distal	6	no	14.690	14.075	EPSD	TCGA;ICGC	10.919	Down-regulation
Other_PLK_PLK1_PLK1_ST	O95251	KAT7	P53350	PLK1	S21	D17H	17	Missense	distal	-4	no	12.134	12.063	EPSD	TCGA;ICGC;COSMIC	10.919	Down-regulation
Other_PLK_PLK1_PLK1_ST	O95251	KAT7	P53350	PLK1	S21	S18F	18	Missense	distal	-3	no	12.134	11.505	EPSD	TCGA;ICGC;COSMIC	10.919	Down-regulation
Other_PLK_PLK1_PLK1_ST	O95251	KAT7	P53350	PLK1	S21	D17Y	17	Missense	distal	-4	no	12.134	11.641	EPSD	TCGA;ICGC	10.919	Down-regulation
Other_PLK_PLK1_PLK1_ST	O95251	KAT7	P53350	PLK1	S21	L24F	24	Missense	distal	3	no	12.134	12.341	EPSD	TCGA;ICGC	10.919	Up-regulation
Other_PLK_PLK1_PLK1_ST	O95251	KAT7	P53350	PLK1	T27	S30P	30	Missense	distal	3	no	13.898	13.920	EPSD	TCGA;ICGC;COSMIC	10.919	Up-regulation
Other_PLK_PLK1_PLK1_ST	O95251	KAT7	P53350	PLK1	T27	L24F	24	Missense	distal	-3	no	13.898	12.495	EPSD	TCGA;ICGC	10.919	Down-regulation
Other_PLK_PLK1_PLK1_ST	O95251	KAT7	P53350	PLK1	S30	S30P	30	Missense	central	0	yes	11.536	0.000	EPSD	TCGA;ICGC;COSMIC	10.919	Loss
Other_PLK_PLK1_PLK1_ST	O95251	KAT7	P53350	PLK1	S30	L24F	24	Missense	distal	-6	no	11.536	11.353	EPSD	TCGA;ICGC	10.919	Down-regulation
Other_PLK_PLK1_PLK1_ST	O95251	KAT7	P53350	PLK1	S50	S52I	52	Missense	proximal	2	no	10.560	10.981	EPSD	TCGA;ICGC;COSMIC	10.919	Gain
Other_PLK_PLK1_PLK1_ST	O95251	KAT7	P53350	PLK1	S52	S45F	45	Missense	distal	-7	no	13.226	12.769	EPSD	TCGA;ICGC;COSMIC	10.919	Down-regulation
Other_PLK_PLK1_PLK1_ST	O95251	KAT7	P53350	PLK1	S52	S50I	50	Missense	proximal	-2	no	13.226	12.662	EPSD	TCGA;ICGC;COSMIC	10.919	Down-regulation
Other_PLK_PLK1_PLK1_ST	O95251	KAT7	P53350	PLK1	S52	D55N	55	Missense	distal	3	no	13.226	13.026	EPSD	TCGA;ICGC;COSMIC	10.919	Down-regulation
Other_PLK_PLK1_PLK1_ST	O95251	KAT7	P53350	PLK1	S52	S56F	56	Missense	distal	4	no	13.226	12.412	EPSD	TCGA;ICGC;COSMIC	10.919	Down-regulation
Other_PLK_PLK1_PLK1_ST	O95251	KAT7	P53350	PLK1	S52	S52I	52	Missense	central	0	yes	13.226	0.000	EPSD	TCGA;ICGC;COSMIC	10.919	Loss
Other_PLK_PLK1_PLK1_ST	O95251	KAT7	P53350	PLK1	S57	S50I	50	Missense	distal	-7	no	13.232	12.770	PhosphoSitePlus	TCGA;ICGC;COSMIC	10.919	Down-regulation
Other_PLK_PLK1_PLK1_ST	O95251	KAT7	P53350	PLK1	S57	D55N	55	Missense	proximal	-2	no	13.232	11.989	PhosphoSitePlus	TCGA;ICGC;COSMIC	10.919	Down-regulation
Other_PLK_PLK1_PLK1_ST	O95251	KAT7	P53350	PLK1	S57	S56F	56	Missense	proximal	-1	no	13.232	12.693	PhosphoSitePlus	TCGA;ICGC;COSMIC	10.919	Down-regulation
Other_PLK_PLK1_PLK1_ST	O95251	KAT7	P53350	PLK1	S57	N61T	61	Missense	distal	4	no	13.232	13.275	PhosphoSitePlus	TCGA;ICGC;COSMIC	10.919	Up-regulation
Other_PLK_PLK1_PLK1_ST	O95251	KAT7	P53350	PLK1	S57	S64Y	64	Missense	distal	7	no	13.232	13.287	PhosphoSitePlus	TCGA;ICGC;COSMIC	10.919	Up-regulation
Other_PLK_PLK1_PLK1_ST	O95251	KAT7	P53350	PLK1	S57	S52I	52	Missense	distal	-5	no	13.232	13.600	PhosphoSitePlus	TCGA;ICGC;COSMIC	10.919	Up-regulation
Other_PLK_PLK1_PLK1_ST	O95251	KAT7	P53350	PLK1	S57	R60Q	60	Missense	distal	3	no	13.232	13.428	PhosphoSitePlus	TCGA;ICGC	10.919	Up-regulation
Other_PLK_PLK1_PLK1_ST	O95251	KAT7	P53350	PLK1	S57	S64P	64	Missense	distal	7	no	13.232	13.259	PhosphoSitePlus	TCGA;ICGC	10.919	Up-regulation
Other_PLK_PLK1_PLK1_ST	O95251	KAT7	P53350	PLK1	T74	R75I	75	Missense	proximal	1	no	8.716	11.639	EPSD	TCGA;ICGC;COSMIC	10.919	Gain
Other_PLK_PLK1_PLK1_ST	O95251	KAT7	P53350	PLK1	S111	V108F	108	Missense	distal	-3	no	11.300	10.547	EPSD	TCGA;ICGC;COSMIC	10.919	Loss
Other_PLK_PLK1_PLK1_ST	O95251	KAT7	P53350	PLK1	S111	V107M	107	Missense	distal	-4	no	11.300	11.124	EPSD	TCGA;ICGC;COSMIC	10.919	Down-regulation
Other_PLK_PLK1_PLK1_ST	O95251	KAT7	P53350	PLK1	S111	Q106R	106	Missense	distal	-5	no	11.300	12.039	EPSD	TCGA;ICGC	10.919	Up-regulation
Other_PLK_PLK1_PLK1_ST	O95251	KAT7	P53350	PLK1	S124	R127Q	127	Missense	distal	3	no	12.875	13.071	EPSD	TCGA;ICGC;COSMIC;GDSC;CCLE	10.919	Up-regulation
Other_PLK_PLK1_PLK1_ST	O95251	KAT7	P53350	PLK1	S144	H149Y	149	Missense	distal	5	no	11.413	11.562	EPSD	TCGA;ICGC;COSMIC	10.919	Up-regulation
Other_PLK_PLK1_PLK1_ST	O95251	KAT7	P53350	PLK1	S148	H149Y	149	Missense	proximal	1	no	10.821	11.326	EPSD	TCGA;ICGC;COSMIC	10.919	Gain
Other_PLK_PLK1_PLK1_ST	O95251	KAT7	P53350	PLK1	S152	H149Y	149	Missense	distal	-3	no	12.663	12.972	EPSD	TCGA;ICGC;COSMIC	10.919	Up-regulation
Other_PLK_PLK1_PLK1_ST	O95251	KAT7	P53350	PLK1	S405	R400H	400	Missense	distal	-5	no	11.138	10.335	EPSD	TCGA;COSMIC	10.919	Loss
Other_PLK_PLK1_PLK1_ST	O95251	KAT7	P53350	PLK1	S466	K464N	464	Missense	proximal	-2	no	10.348	12.377	EPSD	TCGA;COSMIC;GDSC;CCLE	10.919	Gain
Other_PLK_PLK1_PLK1_ST	O95251	KAT7	P53350	PLK1	S540	I544M	544	Missense	distal	4	no	11.373	11.615	EPSD	TCGA;COSMIC	10.919	Up-regulation
Other_PLK_PLK1_PLK1_ST	O95251	KAT7	P53350	PLK1	S540	G536A	536	Missense	distal	-4	no	11.373	12.066	EPSD	TCGA;COSMIC	10.919	Up-regulation
Other_PLK_PLK1_PLK1_ST	O95251	KAT7	P53350	PLK1	S540	E538D	538	Missense	proximal	-2	no	11.373	11.766	EPSD	TCGA;COSMIC	10.919	Up-regulation
Other_PLK_PLK1_PLK1_ST	O95251	KAT7	P53350	PLK1	S545	I544M	544	Missense	proximal	-1	no	11.990	12.044	EPSD	TCGA;COSMIC	10.919	Up-regulation
Other_PLK_PLK1_PLK1_ST	O95251	KAT7	P53350	PLK1	S545	A549S	549	Missense	distal	4	no	11.990	12.188	EPSD	TCGA;COSMIC	10.919	Up-regulation
Other_PLK_PLK1_PLK1_ST	O95251	KAT7	P53350	PLK1	S545	A549V	549	Missense	distal	4	no	11.990	11.726	EPSD	TCGA;COSMIC	10.919	Down-regulation
Other_PLK_PLK1_PLK1_ST	O95251	KAT7	P53350	PLK1	S545	T548M	548	Missense	distal	3	no	11.990	11.837	EPSD	TCGA;COSMIC	10.919	Down-regulation
Other_PLK_PLK1_PLK1_ST	O95251	KAT7	P53350	PLK1	S545	E538D	538	Missense	distal	-7	no	11.990	11.701	EPSD	TCGA;COSMIC	10.919	Down-regulation
Other_PLK_PLK1_PLK1_ST	Q13127	REST	P53350	PLK1	S85	P78S	78	Missense	distal	-7	no	13.632	13.843	EPSD	TCGA;ICGC;COSMIC	10.919	Up-regulation
Other_PLK_PLK1_PLK1_ST	Q13127	REST	P53350	PLK1	S85	V79A	79	Missense	distal	-6	no	13.632	13.871	EPSD	TCGA;ICGC;COSMIC	10.919	Up-regulation
Other_PLK_PLK1_PLK1_ST	Q13127	REST	P53350	PLK1	S85	E88K	88	Missense	distal	3	no	13.632	13.426	EPSD	TCGA;ICGC;COSMIC	10.919	Down-regulation
Other_PLK_PLK1_PLK1_ST	Q13127	REST	P53350	PLK1	S96	P103R	103	Missense	distal	7	no	11.172	11.160	EPSD	TCGA;ICGC;COSMIC	10.919	Down-regulation
Other_PLK_PLK1_PLK1_ST	Q13127	REST	P53350	PLK1	S204	D210N	210	Missense	distal	6	no	13.943	13.723	EPSD	TCGA;ICGC;COSMIC	10.919	Down-regulation
Other_PLK_PLK1_PLK1_ST	Q13127	REST	P53350	PLK1	S204	D210Y	210	Missense	distal	6	no	13.943	13.144	EPSD	TCGA;ICGC	10.919	Down-regulation
Other_PLK_PLK1_PLK1_ST	Q13127	REST	P53350	PLK1	S204	F211V	211	Missense	distal	7	no	13.943	13.922	EPSD	TCGA;ICGC;COSMIC	10.919	Down-regulation
Other_PLK_PLK1_PLK1_ST	Q13127	REST	P53350	PLK1	S495	V499E	499	Missense	distal	4	no	10.617	11.067	EPSD	TCGA;ICGC;COSMIC	10.919	Gain
Other_PLK_PLK1_PLK1_ST	Q13127	REST	P53350	PLK1	S555	P559S	559	Missense	distal	4	no	11.914	12.236	EPSD	TCGA;ICGC;COSMIC	10.919	Up-regulation
Other_PLK_PLK1_PLK1_ST	Q13127	REST	P53350	PLK1	S555	P559L	559	Missense	distal	4	no	11.914	11.623	EPSD	TCGA;ICGC;COSMIC	10.919	Down-regulation
Other_PLK_PLK1_PLK1_ST	Q13127	REST	P53350	PLK1	S750	P752L	752	Missense	proximal	2	no	9.542	11.090	EPSD	TCGA;ICGC;COSMIC	10.919	Gain
Other_PLK_PLK1_PLK1_ST	Q13127	REST	P53350	PLK1	S942	N935H	935	Missense	distal	-7	no	14.159	14.251	EPSD	TCGA;ICGC;COSMIC	10.919	Up-regulation
Other_PLK_PLK1_PLK1_ST	Q13127	REST	P53350	PLK1	S1024	S1027G	1027	Missense	distal	3	no	12.526	12.529	EPSD	TCGA;ICGC;COSMIC	10.919	Up-regulation
Other_PLK_PLK1_PLK1_ST	Q13127	REST	P53350	PLK1	S1030	S1027G	1027	Missense	distal	-3	no	12.929	13.702	PhosphoSitePlus	TCGA;ICGC;COSMIC	10.919	Up-regulation
Other_PLK_PLK1_PLK1_ST	Q13127	REST	P53350	PLK1	S1030	R1036W	1036	Missense	distal	6	no	12.929	12.950	PhosphoSitePlus	TCGA;ICGC	10.919	Up-regulation
Other_PLK_PLK1_PLK1_ST	P30622	CLIP1	P53350	PLK1	T36	V33L	33	Missense	distal	-3	no	12.108	12.759	EPSD	TCGA;ICGC;COSMIC	10.919	Up-regulation
Other_PLK_PLK1_PLK1_ST	P30622	CLIP1	P53350	PLK1	S147	C150F	150	Missense	distal	3	no	11.257	11.381	EPSD	TCGA;ICGC;COSMIC	10.919	Up-regulation
Other_PLK_PLK1_PLK1_ST	P30622	CLIP1	P53350	PLK1	S180	P184S	184	Missense	distal	4	no	10.736	11.058	EPSD	TCGA;ICGC;COSMIC	10.919	Gain
Other_PLK_PLK1_PLK1_ST	P30622	CLIP1	P53350	PLK1	S180	P174T	174	Missense	distal	-6	no	10.736	11.257	EPSD	TCGA;ICGC;COSMIC	10.919	Gain
Other_PLK_PLK1_PLK1_ST	P30622	CLIP1	P53350	PLK1	S200	S200L	200	Missense	central	0	yes	14.269	0.000	EPSD	TCGA;ICGC;COSMIC	10.919	Loss
Other_PLK_PLK1_PLK1_ST	P30622	CLIP1	P53350	PLK1	S200	S204L	204	Missense	distal	4	no	14.269	13.656	EPSD	TCGA	10.919	Down-regulation
Other_PLK_PLK1_PLK1_ST	P30622	CLIP1	P53350	PLK1	S200	K206N	206	Missense	distal	6	no	14.269	14.267	EPSD	TCGA;ICGC	10.919	Down-regulation
Other_PLK_PLK1_PLK1_ST	P30622	CLIP1	P53350	PLK1	T302	R298Q	298	Missense	distal	-4	no	11.554	11.842	EPSD	TCGA;ICGC;COSMIC	10.919	Up-regulation
Other_PLK_PLK1_PLK1_ST	P30622	CLIP1	P53350	PLK1	T302	A305T	305	Missense	distal	3	no	11.554	11.593	EPSD	TCGA;COSMIC	10.919	Up-regulation
Other_PLK_PLK1_PLK1_ST	P30622	CLIP1	P53350	PLK1	T302	A305G	305	Missense	distal	3	no	11.554	11.733	EPSD	TCGA;ICGC;COSMIC	10.919	Up-regulation
Other_PLK_PLK1_PLK1_ST	P30622	CLIP1	P53350	PLK1	T302	R298P	298	Missense	distal	-4	no	11.554	11.998	EPSD	TCGA;ICGC;COSMIC	10.919	Up-regulation
Other_PLK_PLK1_PLK1_ST	P30622	CLIP1	P53350	PLK1	S306	A305T	305	Missense	proximal	-1	no	11.868	11.588	EPSD	TCGA;COSMIC	10.919	Down-regulation
Other_PLK_PLK1_PLK1_ST	P30622	CLIP1	P53350	PLK1	S306	A305G	305	Missense	proximal	-1	no	11.868	10.538	EPSD	TCGA;ICGC;COSMIC	10.919	Loss
Other_PLK_PLK1_PLK1_ST	P30622	CLIP1	P53350	PLK1	S312	A305T	305	Missense	distal	-7	no	11.365	11.710	EPSD;PhosphoSitePlus	TCGA;COSMIC	10.919	Up-regulation
Other_PLK_PLK1_PLK1_ST	P30622	CLIP1	P53350	PLK1	S312	A305G	305	Missense	distal	-7	no	11.365	11.023	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	10.919	Down-regulation
Other_PLK_PLK1_PLK1_ST	P30622	CLIP1	P53350	PLK1	S320	S321L	321	Missense	proximal	1	no	9.176	11.144	EPSD	TCGA;ICGC;COSMIC	10.919	Gain
Other_PLK_PLK1_PLK1_ST	P30622	CLIP1	P53350	PLK1	S325	S321L	321	Missense	distal	-4	no	12.340	12.146	EPSD	TCGA;ICGC;COSMIC	10.919	Down-regulation
Other_PLK_PLK1_PLK1_ST	P30622	CLIP1	P53350	PLK1	S325	A323V	323	Missense	proximal	-2	no	12.340	12.299	EPSD	TCGA;COSMIC	10.919	Down-regulation
Other_PLK_PLK1_PLK1_ST	P30622	CLIP1	P53350	PLK1	T339	S340F	340	Missense	proximal	1	no	8.684	11.732	EPSD	TCGA;ICGC;COSMIC	10.919	Gain
Other_PLK_PLK1_PLK1_ST	P30622	CLIP1	P53350	PLK1	S383	V385L	385	Missense	proximal	2	no	11.438	11.306	EPSD	TCGA;ICGC;COSMIC	10.919	Down-regulation
Other_PLK_PLK1_PLK1_ST	P30622	CLIP1	P53350	PLK1	S383	T382M	382	Missense	proximal	-1	no	11.438	12.257	EPSD	TCGA;COSMIC	10.919	Up-regulation
Other_PLK_PLK1_PLK1_ST	P30622	CLIP1	P53350	PLK1	S449	E446Q	446	Missense	distal	-3	no	12.366	12.692	EPSD	TCGA;ICGC;COSMIC	10.919	Up-regulation
Other_PLK_PLK1_PLK1_ST	P30622	CLIP1	P53350	PLK1	T501	E508V	508	Missense	distal	7	no	11.595	11.665	EPSD	TCGA;COSMIC	10.919	Up-regulation
Other_PLK_PLK1_PLK1_ST	P30622	CLIP1	P53350	PLK1	T501	L494F	494	Missense	distal	-7	no	11.595	11.442	EPSD	TCGA	10.919	Down-regulation
Other_PLK_PLK1_PLK1_ST	P30622	CLIP1	P53350	PLK1	T505	E508V	508	Missense	distal	3	no	11.629	11.601	EPSD	TCGA;COSMIC	10.919	Down-regulation
Other_PLK_PLK1_PLK1_ST	P30622	CLIP1	P53350	PLK1	S553	E551D	551	Missense	proximal	-2	no	13.493	13.887	EPSD	TCGA;COSMIC	10.919	Up-regulation
Other_PLK_PLK1_PLK1_ST	P30622	CLIP1	P53350	PLK1	S553	E557G	557	Missense	distal	4	no	13.493	13.419	EPSD	TCGA;COSMIC	10.919	Down-regulation
Other_PLK_PLK1_PLK1_ST	P30622	CLIP1	P53350	PLK1	S553	S554F	554	Missense	proximal	1	no	13.493	16.541	EPSD	TCGA;COSMIC	10.919	Up-regulation
Other_PLK_PLK1_PLK1_ST	P30622	CLIP1	P53350	PLK1	S709	S715L	715	Missense	distal	6	no	12.650	12.689	EPSD	TCGA	10.919	Up-regulation
Other_PLK_PLK1_PLK1_ST	P30622	CLIP1	P53350	PLK1	S937	S942F	942	Missense	distal	5	no	11.581	11.675	EPSD	TCGA;COSMIC	10.919	Up-regulation
Other_PLK_PLK1_PLK1_ST	P30622	CLIP1	P53350	PLK1	S937	Q943H	943	Missense	distal	6	no	11.581	11.077	EPSD	TCGA	10.919	Down-regulation
Other_PLK_PLK1_PLK1_ST	P30622	CLIP1	P53350	PLK1	S937	S937L	937	Missense	central	0	yes	11.581	0.000	EPSD	TCGA;COSMIC	10.919	Loss
Other_PLK_PLK1_PLK1_ST	P30622	CLIP1	P53350	PLK1	S941	S942F	942	Missense	proximal	1	no	10.170	13.218	EPSD	TCGA;COSMIC	10.919	Gain
Other_PLK_PLK1_PLK1_ST	P30622	CLIP1	P53350	PLK1	S973	S978T	978	Missense	distal	5	no	12.479	11.874	EPSD	TCGA	10.919	Down-regulation
Other_PLK_PLK1_PLK1_ST	P30622	CLIP1	P53350	PLK1	S973	E980D	980	Missense	distal	7	no	12.479	12.475	EPSD	TCGA	10.919	Down-regulation
Other_PLK_PLK1_PLK1_ST	P30622	CLIP1	P53350	PLK1	S973	K977N	977	Missense	distal	4	no	12.479	12.628	EPSD	TCGA	10.919	Up-regulation
Other_PLK_PLK1_PLK1_ST	P30622	CLIP1	P53350	PLK1	T983	S978T	978	Missense	distal	-5	no	11.169	11.384	EPSD	TCGA	10.919	Up-regulation
Other_PLK_PLK1_PLK1_ST	P30622	CLIP1	P53350	PLK1	T983	Q988R	988	Missense	distal	5	no	11.169	11.965	EPSD	TCGA;COSMIC	10.919	Up-regulation
Other_PLK_PLK1_PLK1_ST	P30622	CLIP1	P53350	PLK1	T983	E980D	980	Missense	distal	-3	no	11.169	11.628	EPSD	TCGA	10.919	Up-regulation
Other_PLK_PLK1_PLK1_ST	P30622	CLIP1	P53350	PLK1	T983	K977N	977	Missense	distal	-6	no	11.169	11.427	EPSD	TCGA	10.919	Up-regulation
Other_PLK_PLK1_PLK1_ST	P30622	CLIP1	P53350	PLK1	S989	Q988R	988	Missense	proximal	-1	no	11.026	10.422	EPSD	TCGA;COSMIC	10.919	Loss
Other_PLK_PLK1_PLK1_ST	P30622	CLIP1	P53350	PLK1	S1066	A1061T	1061	Missense	distal	-5	no	11.272	11.203	EPSD	TCGA;COSMIC	10.919	Down-regulation
Other_PLK_PLK1_PLK1_ST	P30622	CLIP1	P53350	PLK1	T1112	S1108F	1108	Missense	distal	-4	no	12.379	12.061	EPSD	TCGA;COSMIC	10.919	Down-regulation
Other_PLK_PLK1_PLK1_ST	P30622	CLIP1	P53350	PLK1	S1204	E1201K	1201	Missense	distal	-3	no	11.870	12.410	EPSD	TCGA;COSMIC	10.919	Up-regulation
Other_PLK_PLK1_PLK1_ST	P30622	CLIP1	P53350	PLK1	S1204	E1200D	1200	Missense	distal	-4	no	11.870	11.686	EPSD	TCGA	10.919	Down-regulation
Other_PLK_PLK1_PLK1_ST	P30622	CLIP1	P53350	PLK1	S1204	S1204Y	1204	Missense	central	0	yes	11.870	0.000	EPSD	TCGA;COSMIC	10.919	Loss
Other_PLK_PLK1_PLK1_ST	Q76N32	CEP68	P53350	PLK1	S126	T123S	123	Missense	distal	-3	no	11.067	10.690	EPSD	TCGA;ICGC;COSMIC	10.919	Loss
Other_PLK_PLK1_PLK1_ST	Q76N32	CEP68	P53350	PLK1	S226	S227F	227	Missense	proximal	1	no	9.701	12.749	EPSD	TCGA;ICGC;COSMIC	10.919	Gain
Other_PLK_PLK1_PLK1_ST	Q76N32	CEP68	P53350	PLK1	S237	P236H	236	Missense	proximal	-1	no	10.130	11.364	EPSD	TCGA;ICGC;COSMIC	10.919	Gain
Other_PLK_PLK1_PLK1_ST	Q76N32	CEP68	P53350	PLK1	S260	F254L	254	Missense	distal	-6	no	12.703	12.886	EPSD	TCGA;ICGC;COSMIC	10.919	Up-regulation
Other_PLK_PLK1_PLK1_ST	Q76N32	CEP68	P53350	PLK1	S260	G257V	257	Missense	distal	-3	no	12.703	12.054	EPSD	TCGA;ICGC;COSMIC	10.919	Down-regulation
Other_PLK_PLK1_PLK1_ST	Q76N32	CEP68	P53350	PLK1	S338	S340F	340	Missense	proximal	2	no	13.169	12.617	EPSD	TCGA;ICGC;COSMIC	10.919	Down-regulation
Other_PLK_PLK1_PLK1_ST	Q76N32	CEP68	P53350	PLK1	S354	V353I	353	Missense	proximal	-1	no	11.324	12.297	EPSD	TCGA;ICGC	10.919	Up-regulation
Other_PLK_PLK1_PLK1_ST	Q76N32	CEP68	P53350	PLK1	S354	P350L	350	Missense	distal	-4	no	11.324	11.252	EPSD	TCGA;ICGC	10.919	Down-regulation
Other_PLK_PLK1_PLK1_ST	Q76N32	CEP68	P53350	PLK1	S374	S368C	368	Missense	distal	-6	no	13.003	11.800	EPSD	TCGA;ICGC;COSMIC	10.919	Down-regulation
Other_PLK_PLK1_PLK1_ST	Q76N32	CEP68	P53350	PLK1	S478	E477K	477	Missense	proximal	-1	no	13.046	12.475	EPSD	TCGA;ICGC;COSMIC	10.919	Down-regulation
Other_PLK_PLK1_PLK1_ST	Q76N32	CEP68	P53350	PLK1	S478	K471R	471	Missense	distal	-7	no	13.046	12.914	EPSD	TCGA;ICGC	10.919	Down-regulation
Other_PLK_PLK1_PLK1_ST	P42898	MTHFR	P53350	PLK1	S26	S30L	30	Missense	distal	4	no	12.009	11.396	EPSD	TCGA;ICGC;COSMIC	10.919	Down-regulation
Other_PLK_PLK1_PLK1_ST	P42898	MTHFR	P53350	PLK1	S392	S393F	393	Missense	proximal	1	no	8.862	11.910	EPSD	TCGA;COSMIC	10.919	Gain
Other_PLK_PLK1_PLK1_ST	P42898	MTHFR	P53350	PLK1	S465	P459L	459	Missense	distal	-6	no	13.975	14.264	EPSD	TCGA;COSMIC	10.919	Up-regulation
Other_PLK_PLK1_PLK1_ST	P42898	MTHFR	P53350	PLK1	S465	A461V	461	Missense	distal	-4	no	13.975	13.835	EPSD	TCGA;COSMIC	10.919	Down-regulation
Other_PLK_PLK1_PLK1_ST	Q15435	PPP1R7	P53350	PLK1	S24	R21Q	21	Missense	distal	-3	no	12.419	11.744	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	10.919	Down-regulation
Other_PLK_PLK1_PLK1_ST	Q15435	PPP1R7	P53350	PLK1	S24	E31K	31	Missense	distal	7	no	12.419	12.492	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	10.919	Up-regulation
Other_PLK_PLK1_PLK1_ST	Q15435	PPP1R7	P53350	PLK1	S24	E23K	23	Missense	proximal	-1	no	12.419	11.848	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	10.919	Down-regulation
Other_PLK_PLK1_PLK1_ST	Q15435	PPP1R7	P53350	PLK1	S24	G28S	28	Missense	distal	4	no	12.419	12.504	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	10.919	Up-regulation
Other_PLK_PLK1_PLK1_ST	Q15435	PPP1R7	P53350	PLK1	S24	R21W	21	Missense	distal	-3	no	12.419	11.638	EPSD;PhosphoSitePlus	TCGA;ICGC	10.919	Down-regulation
Other_PLK_PLK1_PLK1_ST	Q15435	PPP1R7	P53350	PLK1	S27	R21Q	21	Missense	distal	-6	no	12.421	12.868	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	10.919	Up-regulation
Other_PLK_PLK1_PLK1_ST	Q15435	PPP1R7	P53350	PLK1	S27	E31K	31	Missense	distal	4	no	12.421	12.047	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	10.919	Down-regulation
Other_PLK_PLK1_PLK1_ST	Q15435	PPP1R7	P53350	PLK1	S27	E23K	23	Missense	distal	-4	no	12.421	12.038	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	10.919	Down-regulation
Other_PLK_PLK1_PLK1_ST	Q15435	PPP1R7	P53350	PLK1	S27	G32W	32	Missense	distal	5	no	12.421	12.324	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	10.919	Down-regulation
Other_PLK_PLK1_PLK1_ST	Q15435	PPP1R7	P53350	PLK1	S27	G28S	28	Missense	proximal	1	no	12.421	11.484	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	10.919	Down-regulation
Other_PLK_PLK1_PLK1_ST	Q15435	PPP1R7	P53350	PLK1	S27	R21W	21	Missense	distal	-6	no	12.421	11.964	EPSD;PhosphoSitePlus	TCGA;ICGC	10.919	Down-regulation
Other_PLK_PLK1_PLK1_ST	Q15435	PPP1R7	P53350	PLK1	S44	V40M	40	Missense	distal	-4	no	12.279	12.103	PhosphoSitePlus;EPSD	TCGA	10.919	Down-regulation
Other_PLK_PLK1_PLK1_ST	Q15435	PPP1R7	P53350	PLK1	S44	A41T	41	Missense	distal	-3	no	12.279	12.133	PhosphoSitePlus;EPSD	TCGA;ICGC;COSMIC	10.919	Down-regulation
Other_PLK_PLK1_PLK1_ST	Q15435	PPP1R7	P53350	PLK1	S47	V40M	40	Missense	distal	-7	no	13.541	13.408	EPSD;PhosphoSitePlus	TCGA	10.919	Down-regulation
Other_PLK_PLK1_PLK1_ST	Q15435	PPP1R7	P53350	PLK1	S47	A41T	41	Missense	distal	-6	no	13.541	13.474	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	10.919	Down-regulation
Other_PLK_PLK1_PLK1_ST	Q15435	PPP1R7	P53350	PLK1	S47	E52D	52	Missense	distal	5	no	13.541	13.982	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	10.919	Up-regulation
Other_PLK_PLK1_PLK1_ST	Q15435	PPP1R7	P53350	PLK1	S47	R54L	54	Missense	distal	7	no	13.541	13.523	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	10.919	Down-regulation
Other_PLK_PLK1_PLK1_ST	Q15468	STIL	P53350	PLK1	S147	D145N	145	Missense	proximal	-2	no	12.150	10.907	EPSD	TCGA;ICGC	10.919	Loss
Other_PLK_PLK1_PLK1_ST	Q15468	STIL	P53350	PLK1	S162	C158Y	158	Missense	distal	-4	no	10.807	10.933	EPSD	TCGA;ICGC;COSMIC	10.919	Gain
Other_PLK_PLK1_PLK1_ST	Q15468	STIL	P53350	PLK1	T237	L236P	236	Missense	proximal	-1	no	13.348	12.633	EPSD	TCGA;ICGC;COSMIC	10.919	Down-regulation
Other_PLK_PLK1_PLK1_ST	Q15468	STIL	P53350	PLK1	T237	R242H	242	Missense	distal	5	no	13.348	12.697	EPSD	TCGA;ICGC;COSMIC	10.919	Down-regulation
Other_PLK_PLK1_PLK1_ST	Q15468	STIL	P53350	PLK1	S395	S395C	395	Missense	central	0	yes	13.721	0.000	EPSD	TCGA;ICGC;COSMIC	10.919	Loss
Other_PLK_PLK1_PLK1_ST	Q15468	STIL	P53350	PLK1	S395	E398K	398	Missense	distal	3	no	13.721	13.514	EPSD	TCGA;ICGC;COSMIC	10.919	Down-regulation
Other_PLK_PLK1_PLK1_ST	Q15468	STIL	P53350	PLK1	S395	I390V	390	Missense	distal	-5	no	13.721	13.563	EPSD	TCGA;ICGC;COSMIC	10.919	Down-regulation
Other_PLK_PLK1_PLK1_ST	Q15468	STIL	P53350	PLK1	S403	E398K	398	Missense	distal	-5	no	11.467	11.710	EPSD	TCGA;ICGC;COSMIC	10.919	Up-regulation
Other_PLK_PLK1_PLK1_ST	Q15468	STIL	P53350	PLK1	S403	P408H	408	Missense	distal	5	no	11.467	10.773	EPSD	TCGA;ICGC;COSMIC	10.919	Loss
Other_PLK_PLK1_PLK1_ST	Q15468	STIL	P53350	PLK1	S811	G804R	804	Missense	distal	-7	no	12.160	12.359	EPSD	TCGA;ICGC;COSMIC	10.919	Up-regulation
Other_PLK_PLK1_PLK1_ST	Q15468	STIL	P53350	PLK1	S811	E808K	808	Missense	distal	-3	no	12.160	12.700	EPSD	TCGA;ICGC;COSMIC	10.919	Up-regulation
Other_PLK_PLK1_PLK1_ST	Q15468	STIL	P53350	PLK1	S811	D817N	817	Missense	distal	6	no	12.160	11.940	EPSD	TCGA;ICGC;COSMIC	10.919	Down-regulation
Other_PLK_PLK1_PLK1_ST	Q15468	STIL	P53350	PLK1	S811	E805D	805	Missense	distal	-6	no	12.160	11.957	EPSD	TCGA;ICGC;COSMIC	10.919	Down-regulation
Other_PLK_PLK1_PLK1_ST	Q15468	STIL	P53350	PLK1	S952	S953F	953	Missense	proximal	1	no	9.744	12.792	EPSD	TCGA	10.919	Gain
Other_PLK_PLK1_PLK1_ST	Q15468	STIL	P53350	PLK1	S1135	L1129I	1129	Missense	distal	-6	no	12.034	12.437	EPSD	TCGA;ICGC;COSMIC	10.919	Up-regulation
Other_PLK_PLK1_PLK1_ST	Q15468	STIL	P53350	PLK1	S1135	E1139Q	1139	Missense	distal	4	no	12.034	11.630	EPSD	TCGA;ICGC;COSMIC	10.919	Down-regulation
Other_PLK_PLK1_PLK1_ST	Q15468	STIL	P53350	PLK1	S1135	S1132N	1132	Missense	distal	-3	no	12.034	12.223	EPSD	TCGA;ICGC;COSMIC	10.919	Up-regulation
Other_PLK_PLK1_PLK1_ST	Q9UJX5	ANAPC4	P53350	PLK1	S285	Q282H	282	Missense	distal	-3	no	11.078	11.081	EPSD	TCGA;ICGC;COSMIC	10.919	Up-regulation
Other_PLK_PLK1_PLK1_ST	Q9UJX5	ANAPC4	P53350	PLK1	T446	D444Y	444	Missense	proximal	-2	no	14.000	12.458	EPSD	TCGA;COSMIC	10.919	Down-regulation
Other_PLK_PLK1_PLK1_ST	Q92574	TSC1	P53350	PLK1	S115	L116S	116	Missense	proximal	1	no	11.424	9.457	EPSD	TCGA;ICGC;COSMIC	10.919	Loss
Other_PLK_PLK1_PLK1_ST	Q92574	TSC1	P53350	PLK1	T293	D299N	299	Missense	distal	6	no	11.905	11.685	EPSD	TCGA;ICGC;COSMIC	10.919	Down-regulation
Other_PLK_PLK1_PLK1_ST	Q92574	TSC1	P53350	PLK1	T293	T293A	293	Missense	central	0	yes	11.905	0.000	EPSD	TCGA;ICGC;COSMIC	10.919	Loss
Other_PLK_PLK1_PLK1_ST	Q92574	TSC1	P53350	PLK1	T293	R288H	288	Missense	distal	-5	no	11.905	11.103	EPSD	TCGA;ICGC;COSMIC	10.919	Down-regulation
Other_PLK_PLK1_PLK1_ST	Q92574	TSC1	P53350	PLK1	S374	G378A	378	Missense	distal	4	no	11.007	10.894	EPSD	TCGA;ICGC;COSMIC	10.919	Loss
Other_PLK_PLK1_PLK1_ST	Q92574	TSC1	P53350	PLK1	S472	K477N	477	Missense	distal	5	no	15.054	14.731	EPSD	TCGA;ICGC;COSMIC	10.919	Down-regulation
Other_PLK_PLK1_PLK1_ST	Q92574	TSC1	P53350	PLK1	S511	D504N	504	Missense	distal	-7	no	11.428	11.569	EPSD	TCGA;ICGC;COSMIC	10.919	Up-regulation
Other_PLK_PLK1_PLK1_ST	Q92574	TSC1	P53350	PLK1	S511	F507L	507	Missense	distal	-4	no	11.428	11.553	EPSD	TCGA;ICGC;COSMIC	10.919	Up-regulation
Other_PLK_PLK1_PLK1_ST	Q92574	TSC1	P53350	PLK1	S511	R509L	509	Missense	proximal	-2	no	11.428	10.706	EPSD	TCGA;ICGC;COSMIC	10.919	Loss
Other_PLK_PLK1_PLK1_ST	Q92574	TSC1	P53350	PLK1	S526	G528D	528	Missense	proximal	2	no	9.590	11.169	EPSD	TCGA;ICGC;COSMIC	10.919	Gain
Other_PLK_PLK1_PLK1_ST	Q92574	TSC1	P53350	PLK1	S530	G528D	528	Missense	proximal	-2	no	9.942	13.264	EPSD	TCGA;ICGC;COSMIC	10.919	Gain
Other_PLK_PLK1_PLK1_ST	Q92574	TSC1	P53350	PLK1	S530	V531M	531	Missense	proximal	1	no	9.942	11.098	EPSD	TCGA;ICGC;COSMIC	10.919	Gain
Other_PLK_PLK1_PLK1_ST	Q92574	TSC1	P53350	PLK1	S539	P533H	533	Missense	distal	-6	no	10.753	11.387	EPSD	TCGA;ICGC;COSMIC	10.919	Gain
Other_PLK_PLK1_PLK1_ST	Q92574	TSC1	P53350	PLK1	S565	S565N	565	Missense	central	0	yes	14.090	0.000	EPSD	TCGA;ICGC;COSMIC	10.919	Loss
Other_PLK_PLK1_PLK1_ST	Q92574	TSC1	P53350	PLK1	S579	S575F	575	Missense	distal	-4	no	13.965	13.647	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	10.919	Down-regulation
Other_PLK_PLK1_PLK1_ST	Q92574	TSC1	P53350	PLK1	S1025	R1027W	1027	Missense	proximal	2	no	10.841	11.588	EPSD	TCGA;ICGC;COSMIC	10.919	Gain
Other_PLK_PLK1_PLK1_ST	Q92574	TSC1	P53350	PLK1	S1025	R1027Q	1027	Missense	proximal	2	no	10.841	11.166	EPSD	TCGA;ICGC;COSMIC;GDSC;CCLE	10.919	Gain
Other_PLK_PLK1_PLK1_ST	Q92574	TSC1	P53350	PLK1	S1025	A1026T	1026	Missense	proximal	1	no	10.841	11.304	EPSD	TCGA;ICGC;COSMIC	10.919	Gain
Other_PLK_PLK1_PLK1_ST	Q92574	TSC1	P53350	PLK1	S1025	P1021S	1021	Missense	distal	-4	no	10.841	10.963	EPSD	TCGA;ICGC;COSMIC	10.919	Gain
Other_PLK_PLK1_PLK1_ST	Q92574	TSC1	P53350	PLK1	S1030	R1027W	1027	Missense	distal	-3	no	13.134	12.352	EPSD	TCGA;ICGC;COSMIC	10.919	Down-regulation
Other_PLK_PLK1_PLK1_ST	Q92574	TSC1	P53350	PLK1	S1030	R1027Q	1027	Missense	distal	-3	no	13.134	12.459	EPSD	TCGA;ICGC;COSMIC;GDSC;CCLE	10.919	Down-regulation
Other_PLK_PLK1_PLK1_ST	Q92574	TSC1	P53350	PLK1	S1030	A1026T	1026	Missense	distal	-4	no	13.134	12.732	EPSD	TCGA;ICGC;COSMIC	10.919	Down-regulation
Other_PLK_PLK1_PLK1_ST	Q92574	TSC1	P53350	PLK1	S1030	S1032N	1032	Missense	proximal	2	no	13.134	13.347	EPSD	TCGA;ICGC	10.919	Up-regulation
Other_PLK_PLK1_PLK1_ST	Q92574	TSC1	P53350	PLK1	S1071	T1076A	1076	Missense	distal	5	no	11.015	12.186	EPSD	TCGA;ICGC;COSMIC	10.919	Up-regulation
Other_PLK_PLK1_PLK1_ST	Q92574	TSC1	P53350	PLK1	S1071	A1070V	1070	Missense	proximal	-1	no	11.015	10.525	EPSD	TCGA;ICGC;COSMIC	10.919	Loss
Other_PLK_PLK1_PLK1_ST	Q92574	TSC1	P53350	PLK1	S1071	A1072V	1072	Missense	proximal	1	no	11.015	12.453	EPSD	TCGA;ICGC;COSMIC	10.919	Up-regulation
Other_PLK_PLK1_PLK1_ST	Q92574	TSC1	P53350	PLK1	S1100	D1105N	1105	Missense	distal	5	no	12.001	11.248	EPSD	TCGA;ICGC;COSMIC	10.919	Down-regulation
Other_PLK_PLK1_PLK1_ST	Q92574	TSC1	P53350	PLK1	S1100	R1097C	1097	Missense	distal	-3	no	12.001	11.205	EPSD	TCGA;ICGC;COSMIC	10.919	Down-regulation
Other_PLK_PLK1_PLK1_ST	Q92574	TSC1	P53350	PLK1	S1112	D1105N	1105	Missense	distal	-7	no	12.074	12.214	EPSD	TCGA;ICGC;COSMIC	10.919	Up-regulation
Other_PLK_PLK1_PLK1_ST	Q92574	TSC1	P53350	PLK1	S1112	G1108R	1108	Missense	distal	-4	no	12.074	12.161	EPSD	TCGA;ICGC;COSMIC	10.919	Up-regulation
Other_PLK_PLK1_PLK1_ST	O60566	BUB1B	P53350	PLK1	T54	L55V	55	Missense	proximal	1	no	11.353	10.954	EPSD	TCGA;ICGC;COSMIC	10.919	Down-regulation
Other_PLK_PLK1_PLK1_ST	O60566	BUB1B	P53350	PLK1	T54	E48K	48	Missense	distal	-6	no	11.353	10.779	EPSD	TCGA;ICGC	10.919	Loss
Other_PLK_PLK1_PLK1_ST	O60566	BUB1B	P53350	PLK1	S270	R271I	271	Missense	proximal	1	no	11.658	14.581	EPSD	TCGA;ICGC	10.919	Up-regulation
Other_PLK_PLK1_PLK1_ST	O60566	BUB1B	P53350	PLK1	T471	E470K	470	Missense	proximal	-1	no	12.126	11.555	EPSD	TCGA;ICGC	10.919	Down-regulation
Other_PLK_PLK1_PLK1_ST	O60566	BUB1B	P53350	PLK1	S509	C503G	503	Missense	distal	-6	no	10.445	11.102	EPSD	TCGA;ICGC;COSMIC	10.919	Gain
Other_PLK_PLK1_PLK1_ST	O60566	BUB1B	P53350	PLK1	S574	D576H	576	Missense	proximal	2	no	11.781	11.757	EPSD	TCGA;COSMIC	10.919	Down-regulation
Other_PLK_PLK1_PLK1_ST	O60566	BUB1B	P53350	PLK1	S574	D572Y	572	Missense	proximal	-2	no	11.781	10.240	EPSD	TCGA	10.919	Loss
Other_PLK_PLK1_PLK1_ST	O60566	BUB1B	P53350	PLK1	T582	D576H	576	Missense	distal	-6	no	11.089	11.185	EPSD	TCGA;COSMIC	10.919	Up-regulation
Other_PLK_PLK1_PLK1_ST	O60566	BUB1B	P53350	PLK1	T608	A612V	612	Missense	distal	4	no	11.845	11.581	EPSD	TCGA;COSMIC	10.919	Down-regulation
Other_PLK_PLK1_PLK1_ST	O60566	BUB1B	P53350	PLK1	S676	L669P	669	Missense	distal	-7	no	12.761	12.855	EPSD;PhosphoSitePlus	TCGA;COSMIC	10.919	Up-regulation
Other_PLK_PLK1_PLK1_ST	O60566	BUB1B	P53350	PLK1	S676	R677H	677	Missense	proximal	1	no	12.761	14.158	EPSD;PhosphoSitePlus	TCGA;COSMIC;GDSC;CCLE	10.919	Up-regulation
Other_PLK_PLK1_PLK1_ST	O60566	BUB1B	P53350	PLK1	T680	R677H	677	Missense	distal	-3	no	13.297	12.625	EPSD;PhosphoSitePlus	TCGA;COSMIC;GDSC;CCLE	10.919	Down-regulation
Other_PLK_PLK1_PLK1_ST	O60566	BUB1B	P53350	PLK1	S683	R677H	677	Missense	distal	-6	no	11.145	11.604	EPSD	TCGA;COSMIC;GDSC;CCLE	10.919	Up-regulation
Other_PLK_PLK1_PLK1_ST	O60566	BUB1B	P53350	PLK1	S683	S689F	689	Missense	distal	6	no	11.145	10.569	EPSD	TCGA;COSMIC	10.919	Loss
Other_PLK_PLK1_PLK1_ST	O60566	BUB1B	P53350	PLK1	T792	R786T	786	Missense	distal	-6	no	11.538	11.882	EPSD;PhosphoSitePlus	TCGA;COSMIC	10.919	Up-regulation
Other_PLK_PLK1_PLK1_ST	O60566	BUB1B	P53350	PLK1	T792	S797C	797	Missense	distal	5	no	11.538	11.667	EPSD;PhosphoSitePlus	TCGA;COSMIC	10.919	Up-regulation
Other_PLK_PLK1_PLK1_ST	O60566	BUB1B	P53350	PLK1	S884	D882N	882	Missense	proximal	-2	no	13.111	11.868	EPSD	TCGA;COSMIC	10.919	Down-regulation
Other_PLK_PLK1_PLK1_ST	O60566	BUB1B	P53350	PLK1	S884	L890I	890	Missense	distal	6	no	13.111	13.073	EPSD	TCGA;COSMIC	10.919	Down-regulation
Other_PLK_PLK1_PLK1_ST	O60566	BUB1B	P53350	PLK1	T1008	E1006K	1006	Missense	proximal	-2	no	11.310	8.433	PhosphoSitePlus;EPSD	TCGA;COSMIC	10.919	Loss
Other_PLK_PLK1_PLK1_ST	Q14790	CASP8	P53350	PLK1	S16	E12K	12	Missense	distal	-4	no	12.066	11.683	EPSD	TCGA;ICGC;COSMIC	10.919	Down-regulation
Other_PLK_PLK1_PLK1_ST	Q14790	CASP8	P53350	PLK1	S60	L66V	66	Missense	distal	6	no	11.832	11.900	EPSD	TCGA;COSMIC	10.919	Up-regulation
Other_PLK_PLK1_PLK1_ST	Q14790	CASP8	P53350	PLK1	S60	L66R	66	Missense	distal	6	no	11.832	11.486	EPSD	TCGA;COSMIC	10.919	Down-regulation
Other_PLK_PLK1_PLK1_ST	Q14790	CASP8	P53350	PLK1	S305	I298M	298	Missense	distal	-7	no	12.108	12.140	PhosphoSitePlus	TCGA;ICGC;COSMIC	10.919	Up-regulation
Other_PLK_PLK1_PLK1_ST	Q6IBW4	NCAPH2	P53350	PLK1	T50	E46K	46	Missense	distal	-4	no	11.914	11.531	EPSD	TCGA;ICGC;COSMIC	10.919	Down-regulation
Other_PLK_PLK1_PLK1_ST	Q6IBW4	NCAPH2	P53350	PLK1	T50	M51I	51	Missense	proximal	1	no	11.914	10.949	EPSD	TCGA;ICGC;COSMIC	10.919	Down-regulation
Other_PLK_PLK1_PLK1_ST	Q6IBW4	NCAPH2	P53350	PLK1	S108	R101K	101	Missense	distal	-7	no	12.360	12.492	EPSD	TCGA;ICGC;COSMIC	10.919	Up-regulation
Other_PLK_PLK1_PLK1_ST	Q6IBW4	NCAPH2	P53350	PLK1	S108	E115D	115	Missense	distal	7	no	12.360	12.356	EPSD	TCGA;ICGC	10.919	Down-regulation
Other_PLK_PLK1_PLK1_ST	Q6IBW4	NCAPH2	P53350	PLK1	T138	I145T	145	Missense	distal	7	no	12.911	12.864	EPSD	TCGA;ICGC;COSMIC	10.919	Down-regulation
Other_PLK_PLK1_PLK1_ST	Q6IBW4	NCAPH2	P53350	PLK1	T138	I145V	145	Missense	distal	7	no	12.911	12.927	EPSD	TCGA;ICGC;COSMIC	10.919	Up-regulation
Other_PLK_PLK1_PLK1_ST	Q6IBW4	NCAPH2	P53350	PLK1	T183	R176W	176	Missense	distal	-7	no	10.764	11.350	EPSD	TCGA;ICGC;COSMIC	10.919	Gain
Other_PLK_PLK1_PLK1_ST	Q6IBW4	NCAPH2	P53350	PLK1	S428	S428C	428	Missense	central	0	yes	14.911	0.000	EPSD	TCGA;ICGC;COSMIC	10.919	Loss
Other_PLK_PLK1_PLK1_ST	Q6IBW4	NCAPH2	P53350	PLK1	S428	E430G	430	Missense	proximal	2	no	14.911	13.923	EPSD	TCGA;ICGC;COSMIC	10.919	Down-regulation
Other_PLK_PLK1_PLK1_ST	P14635	CCNB1	P53350	PLK1	S126	T124S	124	Missense	proximal	-2	no	11.063	11.601	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	10.919	Up-regulation
Other_PLK_PLK1_PLK1_ST	P14635	CCNB1	P53350	PLK1	S126	M130V	130	Missense	distal	4	no	11.063	11.550	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	10.919	Up-regulation
Other_PLK_PLK1_PLK1_ST	P14635	CCNB1	P53350	PLK1	S126	T132I	132	Missense	distal	6	no	11.063	10.789	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	10.919	Loss
Other_PLK_PLK1_PLK1_ST	P14635	CCNB1	P53350	PLK1	S128	T124S	124	Missense	distal	-4	no	12.040	12.402	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	10.919	Up-regulation
Other_PLK_PLK1_PLK1_ST	P14635	CCNB1	P53350	PLK1	S128	M130V	130	Missense	proximal	2	no	12.040	12.246	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	10.919	Up-regulation
Other_PLK_PLK1_PLK1_ST	P14635	CCNB1	P53350	PLK1	S128	T132I	132	Missense	distal	4	no	12.040	11.041	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	10.919	Down-regulation
Other_PLK_PLK1_PLK1_ST	P14635	CCNB1	P53350	PLK1	S133	M130V	130	Missense	distal	-3	no	12.250	12.122	PhosphoSitePlus;EPSD	TCGA;ICGC;COSMIC	10.919	Down-regulation
Other_PLK_PLK1_PLK1_ST	P14635	CCNB1	P53350	PLK1	S133	A136D	136	Missense	distal	3	no	12.250	12.672	PhosphoSitePlus;EPSD	TCGA;ICGC;COSMIC	10.919	Up-regulation
Other_PLK_PLK1_PLK1_ST	P14635	CCNB1	P53350	PLK1	S133	T132I	132	Missense	proximal	-1	no	12.250	13.014	PhosphoSitePlus;EPSD	TCGA;ICGC;COSMIC	10.919	Up-regulation
Other_PLK_PLK1_PLK1_ST	P14635	CCNB1	P53350	PLK1	S310	A309V	309	Missense	proximal	-1	no	12.316	11.826	EPSD	TCGA;ICGC;COSMIC	10.919	Down-regulation
Other_PLK_PLK1_PLK1_ST	P14635	CCNB1	P53350	PLK1	S310	R307W	307	Missense	distal	-3	no	12.316	11.534	EPSD	TCGA;ICGC;COSMIC;CCLE	10.919	Down-regulation
Other_PLK_PLK1_PLK1_ST	P14635	CCNB1	P53350	PLK1	S310	R307Q	307	Missense	distal	-3	no	12.316	11.641	EPSD	TCGA;ICGC;COSMIC	10.919	Down-regulation
Other_PLK_PLK1_PLK1_ST	P14635	CCNB1	P53350	PLK1	S310	K311T	311	Missense	proximal	1	no	12.316	12.668	EPSD	TCGA;ICGC	10.919	Up-regulation
Other_PLK_PLK1_PLK1_ST	P14635	CCNB1	P53350	PLK1	S370	H367Y	367	Missense	distal	-3	no	13.928	14.237	EPSD	TCGA;ICGC;COSMIC	10.919	Up-regulation
Other_PLK_PLK1_PLK1_ST	P14635	CCNB1	P53350	PLK1	S413	L418M	418	Missense	distal	5	no	11.332	11.775	EPSD	TCGA;ICGC;COSMIC	10.919	Up-regulation
Other_PLK_PLK1_PLK1_ST	Q71F23	CENPU	P53350	PLK1	T23	K21N	21	Missense	proximal	-2	no	9.357	11.386	EPSD	TCGA;COSMIC	10.919	Gain
Other_PLK_PLK1_PLK1_ST	Q71F23	CENPU	P53350	PLK1	T27	R26I	26	Missense	proximal	-1	no	10.866	11.820	EPSD	TCGA;COSMIC	10.919	Gain
Other_PLK_PLK1_PLK1_ST	Q71F23	CENPU	P53350	PLK1	T27	K21N	21	Missense	distal	-6	no	10.866	11.124	EPSD	TCGA;COSMIC	10.919	Gain
Other_PLK_PLK1_PLK1_ST	Q71F23	CENPU	P53350	PLK1	S29	R26I	26	Missense	distal	-3	no	12.278	11.846	EPSD	TCGA;COSMIC	10.919	Down-regulation
Other_PLK_PLK1_PLK1_ST	Q71F23	CENPU	P53350	PLK1	S29	Q36K	36	Missense	distal	7	no	12.278	12.298	EPSD	TCGA;COSMIC	10.919	Up-regulation
Other_PLK_PLK1_PLK1_ST	Q71F23	CENPU	P53350	PLK1	T70	T67A	67	Missense	distal	-3	no	11.412	11.558	EPSD	TCGA;COSMIC	10.919	Up-regulation
Other_PLK_PLK1_PLK1_ST	Q71F23	CENPU	P53350	PLK1	S111	R106I	106	Missense	distal	-5	no	12.162	11.847	EPSD	TCGA;COSMIC	10.919	Down-regulation
Other_PLK_PLK1_PLK1_ST	Q71F23	CENPU	P53350	PLK1	S116	E119K	119	Missense	distal	3	no	11.729	11.523	EPSD	TCGA;COSMIC	10.919	Down-regulation
Other_PLK_PLK1_PLK1_ST	Q71F23	CENPU	P53350	PLK1	S116	S120Y	120	Missense	distal	4	no	11.729	11.486	EPSD	TCGA	10.919	Down-regulation
Other_PLK_PLK1_PLK1_ST	Q71F23	CENPU	P53350	PLK1	S120	E119K	119	Missense	proximal	-1	no	12.755	12.183	EPSD	TCGA;COSMIC	10.919	Down-regulation
Other_PLK_PLK1_PLK1_ST	Q71F23	CENPU	P53350	PLK1	S120	S120Y	120	Missense	central	0	yes	12.755	0.000	EPSD	TCGA	10.919	Loss
Other_PLK_PLK1_PLK1_ST	Q71F23	CENPU	P53350	PLK1	S139	I142T	142	Missense	distal	3	no	13.173	13.006	EPSD	TCGA;COSMIC	10.919	Down-regulation
Other_PLK_PLK1_PLK1_ST	Q71F23	CENPU	P53350	PLK1	T147	R148M	148	Missense	proximal	1	no	8.524	12.412	EPSD	TCGA;COSMIC	10.919	Gain
Other_PLK_PLK1_PLK1_ST	Q71F23	CENPU	P53350	PLK1	S171	E172G	172	Missense	proximal	1	no	11.972	12.219	EPSD	TCGA	10.919	Up-regulation
Other_PLK_PLK1_PLK1_ST	Q71F23	CENPU	P53350	PLK1	S174	E172G	172	Missense	proximal	-2	no	11.609	8.681	EPSD	TCGA	10.919	Loss
Other_PLK_PLK1_PLK1_ST	Q71F23	CENPU	P53350	PLK1	S232	D233N	233	Missense	proximal	1	no	10.982	10.787	EPSD	TCGA;COSMIC;GDSC	10.919	Loss
Other_PLK_PLK1_PLK1_ST	Q71F23	CENPU	P53350	PLK1	S232	H236Y	236	Missense	distal	4	no	10.982	11.260	EPSD	TCGA;COSMIC	10.919	Up-regulation
Other_PLK_PLK1_PLK1_ST	Q71F23	CENPU	P53350	PLK1	S232	I237S	237	Missense	distal	5	no	10.982	10.684	EPSD	TCGA;COSMIC	10.919	Loss
Other_PLK_PLK1_PLK1_ST	Q08050	FOXM1	P53350	PLK1	S28	E26K	26	Missense	proximal	-2	no	11.806	8.929	EPSD	TCGA;ICGC;COSMIC	10.919	Loss
Other_PLK_PLK1_PLK1_ST	Q08050	FOXM1	P53350	PLK1	S28	A23T	23	Missense	distal	-5	no	11.806	11.738	EPSD	TCGA;ICGC;COSMIC	10.919	Down-regulation
Other_PLK_PLK1_PLK1_ST	Q08050	FOXM1	P53350	PLK1	T354	E348D	348	Missense	distal	-6	no	11.477	11.274	EPSD	TCGA;ICGC;COSMIC	10.919	Down-regulation
Other_PLK_PLK1_PLK1_ST	Q08050	FOXM1	P53350	PLK1	T354	T357A	357	Missense	distal	3	no	11.477	11.438	EPSD	TCGA;ICGC	10.919	Down-regulation
Other_PLK_PLK1_PLK1_ST	Q08050	FOXM1	P53350	PLK1	T354	R351W	351	Missense	distal	-3	no	11.477	10.695	EPSD	TCGA;ICGC;COSMIC	10.919	Loss
Other_PLK_PLK1_PLK1_ST	Q08050	FOXM1	P53350	PLK1	S376	R373Q	373	Missense	distal	-3	no	12.742	12.067	EPSD	TCGA;ICGC;COSMIC	10.919	Down-regulation
Other_PLK_PLK1_PLK1_ST	Q08050	FOXM1	P53350	PLK1	S591	L588I	588	Missense	distal	-3	no	12.509	12.134	EPSD	TCGA;ICGC	10.919	Down-regulation
Other_PLK_PLK1_PLK1_ST	Q02750	MAP2K1	P53350	PLK1	S218	V224M	224	Missense	distal	6	no	13.962	13.599	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	10.919	Down-regulation
Other_PLK_PLK1_PLK1_ST	Q02750	MAP2K1	P53350	PLK1	S222	V224M	224	Missense	proximal	2	no	14.742	14.536	PhosphoSitePlus;EPSD	TCGA;ICGC;COSMIC	10.919	Down-regulation
Other_PLK_PLK1_PLK1_ST	Q02750	MAP2K1	P53350	PLK1	S222	R227K	227	Missense	distal	5	no	14.742	14.117	PhosphoSitePlus;EPSD	TCGA;ICGC;COSMIC	10.919	Down-regulation
Other_PLK_PLK1_PLK1_ST	Q99741	CDC6	P53350	PLK1	S20	R21L	21	Missense	proximal	1	no	8.050	11.181	EPSD	TCGA;ICGC;COSMIC	10.919	Gain
Other_PLK_PLK1_PLK1_ST	Q99741	CDC6	P53350	PLK1	S122	S123L	123	Missense	proximal	1	no	9.481	11.449	EPSD	TCGA;ICGC	10.919	Gain
Other_PLK_PLK1_PLK1_ST	Q9Y266	NUDC	P53350	PLK1	S231	G238D	238	Missense	distal	7	no	11.497	11.472	EPSD	TCGA;ICGC	10.919	Down-regulation
Other_PLK_PLK1_PLK1_ST	Q9Y266	NUDC	P53350	PLK1	S232	G238D	238	Missense	distal	6	no	10.915	11.390	EPSD	TCGA;ICGC	10.919	Gain
Other_PLK_PLK1_PLK1_ST	Q9Y266	NUDC	P53350	PLK1	S274	E272K	272	Missense	proximal	-2	no	13.799	10.922	PhosphoSitePlus;EPSD	TCGA;ICGC;COSMIC	10.919	Down-regulation
Other_PLK_PLK1_PLK1_ST	Q9Y266	NUDC	P53350	PLK1	S274	I269N	269	Missense	distal	-5	no	13.799	13.378	PhosphoSitePlus;EPSD	TCGA;ICGC;COSMIC	10.919	Down-regulation
Other_PLK_PLK1_PLK1_ST	Q9Y266	NUDC	P53350	PLK1	S285	Y292H	292	Missense	distal	7	no	11.476	11.407	EPSD	TCGA;ICGC;COSMIC	10.919	Down-regulation
Other_PLK_PLK1_PLK1_ST	Q9Y266	NUDC	P53350	PLK1	S326	F330V	330	Missense	distal	4	no	11.225	11.577	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	10.919	Up-regulation
Other_PLK_PLK1_PLK1_ST	Q9Y2T1	AXIN2	P53350	PLK1	S16	D20N	20	Missense	distal	4	no	11.048	10.809	EPSD	TCGA;ICGC;COSMIC	10.919	Loss
Other_PLK_PLK1_PLK1_ST	Q9Y2T1	AXIN2	P53350	PLK1	S16	P22L	22	Missense	distal	6	no	11.048	10.943	EPSD	TCGA;ICGC;COSMIC	10.919	Down-regulation
Other_PLK_PLK1_PLK1_ST	Q9Y2T1	AXIN2	P53350	PLK1	S16	R23W	23	Missense	distal	7	no	11.048	11.066	EPSD	TCGA;ICGC;COSMIC	10.919	Up-regulation
Other_PLK_PLK1_PLK1_ST	Q9Y2T1	AXIN2	P53350	PLK1	S16	A21V	21	Missense	distal	5	no	11.048	10.309	EPSD	TCGA;ICGC;COSMIC	10.919	Loss
Other_PLK_PLK1_PLK1_ST	Q9Y2T1	AXIN2	P53350	PLK1	S311	M314I	314	Missense	distal	3	no	16.971	17.290	PhosphoSitePlus	TCGA;ICGC;COSMIC	10.919	Up-regulation
Other_PLK_PLK1_PLK1_ST	Q9Y2T1	AXIN2	P53350	PLK1	S311	T315M	315	Missense	distal	4	no	16.971	16.215	PhosphoSitePlus	TCGA;ICGC;COSMIC	10.919	Down-regulation
Other_PLK_PLK1_PLK1_ST	Q9Y2T1	AXIN2	P53350	PLK1	S311	D316H	316	Missense	distal	5	no	16.971	16.516	PhosphoSitePlus	TCGA;ICGC;COSMIC	10.919	Down-regulation
Other_PLK_PLK1_PLK1_ST	Q9Y2T1	AXIN2	P53350	PLK1	S311	L307P	307	Missense	distal	-4	no	16.971	17.043	PhosphoSitePlus	TCGA;ICGC;COSMIC	10.919	Up-regulation
Other_PLK_PLK1_PLK1_ST	Q9Y2T1	AXIN2	P53350	PLK1	S407	R414W	414	Missense	distal	7	no	11.417	11.435	EPSD	TCGA;ICGC;COSMIC	10.919	Up-regulation
Other_PLK_PLK1_PLK1_ST	Q9Y2T1	AXIN2	P53350	PLK1	S407	L409I	409	Missense	proximal	2	no	11.417	11.766	EPSD	TCGA;ICGC	10.919	Up-regulation
Other_PLK_PLK1_PLK1_ST	Q8TEP8	CEP192	P53350	PLK1	S208	S208R	208	Missense	central	0	yes	12.695	0.000	EPSD	TCGA;ICGC;COSMIC	10.919	Loss
Other_PLK_PLK1_PLK1_ST	Q8TEP8	CEP192	P53350	PLK1	S509	S510Y	510	Missense	proximal	1	no	10.764	11.502	EPSD	TCGA;ICGC;COSMIC	10.919	Gain
Other_PLK_PLK1_PLK1_ST	Q8TEP8	CEP192	P53350	PLK1	S516	S510Y	510	Missense	distal	-6	no	11.940	11.087	EPSD	TCGA;ICGC;COSMIC	10.919	Down-regulation
Other_PLK_PLK1_PLK1_ST	Q8TEP8	CEP192	P53350	PLK1	S1602	L1596I	1596	Missense	distal	-6	no	12.525	12.928	EPSD	TCGA;ICGC;COSMIC	10.919	Up-regulation
Other_PLK_PLK1_PLK1_ST	Q99640	PKMYT1	P53350	PLK1	T24	G23D	23	Missense	proximal	-1	no	9.795	12.385	EPSD	TCGA;COSMIC	10.919	Gain
Other_PLK_PLK1_PLK1_ST	Q99640	PKMYT1	P53350	PLK1	S141	R134Q	134	Missense	distal	-7	no	10.773	11.173	EPSD	TCGA	10.919	Gain
Other_PLK_PLK1_PLK1_ST	Q99640	PKMYT1	P53350	PLK1	S426	L427F	427	Missense	proximal	1	no	15.084	16.165	EPSD;PhosphoSitePlus	TCGA	10.919	Up-regulation
Other_PLK_PLK1_PLK1_ST	Q99640	PKMYT1	P53350	PLK1	S426	L427I	427	Missense	proximal	1	no	15.084	14.876	EPSD;PhosphoSitePlus	TCGA	10.919	Down-regulation
Other_PLK_PLK1_PLK1_ST	Q99640	PKMYT1	P53350	PLK1	S469	A465V	465	Missense	distal	-4	no	13.246	13.106	EPSD	TCGA;COSMIC;GDSC	10.919	Down-regulation
Other_PLK_PLK1_PLK1_ST	Q99640	PKMYT1	P53350	PLK1	S469	A465D	465	Missense	distal	-4	no	13.246	13.012	EPSD	TCGA;COSMIC	10.919	Down-regulation
Other_PLK_PLK1_PLK1_ST	O60216	RAD21	P53350	PLK1	S40	E42Q	42	Missense	proximal	2	no	12.100	12.288	EPSD	TCGA;ICGC;COSMIC	10.919	Up-regulation
Other_PLK_PLK1_PLK1_ST	O60216	RAD21	P53350	PLK1	S40	V41M	41	Missense	proximal	1	no	12.100	13.256	EPSD	TCGA;ICGC	10.919	Up-regulation
Other_PLK_PLK1_PLK1_ST	O60216	RAD21	P53350	PLK1	S43	E42Q	42	Missense	proximal	-1	no	10.970	10.641	EPSD	TCGA;ICGC;COSMIC	10.919	Loss
Other_PLK_PLK1_PLK1_ST	O60216	RAD21	P53350	PLK1	S43	V41M	41	Missense	proximal	-2	no	10.970	10.474	EPSD	TCGA;ICGC	10.919	Loss
Other_PLK_PLK1_PLK1_ST	O60216	RAD21	P53350	PLK1	S46	M51I	51	Missense	distal	5	no	10.822	11.023	EPSD	TCGA;ICGC;COSMIC	10.919	Gain
Other_PLK_PLK1_PLK1_ST	O60216	RAD21	P53350	PLK1	S134	V129L	129	Missense	distal	-5	no	11.727	12.180	EPSD	TCGA;ICGC;COSMIC	10.919	Up-regulation
Other_PLK_PLK1_PLK1_ST	O60216	RAD21	P53350	PLK1	S138	E142D	142	Missense	distal	4	no	11.704	11.718	EPSD	TCGA;ICGC;COSMIC	10.919	Up-regulation
Other_PLK_PLK1_PLK1_ST	O60216	RAD21	P53350	PLK1	T144	G150V	150	Missense	distal	6	no	15.810	16.122	EPSD	TCGA;ICGC;COSMIC	10.919	Up-regulation
Other_PLK_PLK1_PLK1_ST	O60216	RAD21	P53350	PLK1	T144	E147K	147	Missense	distal	3	no	15.810	15.604	EPSD	TCGA;ICGC;COSMIC	10.919	Down-regulation
Other_PLK_PLK1_PLK1_ST	O60216	RAD21	P53350	PLK1	T144	E142D	142	Missense	proximal	-2	no	15.810	16.204	EPSD	TCGA;ICGC;COSMIC	10.919	Up-regulation
Other_PLK_PLK1_PLK1_ST	O60216	RAD21	P53350	PLK1	S153	G150V	150	Missense	distal	-3	no	14.190	13.541	EPSD	TCGA;ICGC;COSMIC	10.919	Down-regulation
Other_PLK_PLK1_PLK1_ST	O60216	RAD21	P53350	PLK1	S153	E147K	147	Missense	distal	-6	no	14.190	13.616	EPSD	TCGA;ICGC;COSMIC	10.919	Down-regulation
Other_PLK_PLK1_PLK1_ST	O60216	RAD21	P53350	PLK1	S153	I154T	154	Missense	proximal	1	no	14.190	13.023	EPSD	TCGA;ICGC;COSMIC	10.919	Down-regulation
Other_PLK_PLK1_PLK1_ST	O60216	RAD21	P53350	PLK1	S280	S280L	280	Missense	central	0	yes	10.971	0.000	EPSD	TCGA;ICGC;COSMIC	10.919	Loss
Other_PLK_PLK1_PLK1_ST	O60216	RAD21	P53350	PLK1	S280	V284I	284	Missense	distal	4	no	10.971	10.241	EPSD	TCGA;ICGC;COSMIC	10.919	Loss
Other_PLK_PLK1_PLK1_ST	O60216	RAD21	P53350	PLK1	S280	D276H	276	Missense	distal	-4	no	10.971	10.899	EPSD	TCGA;ICGC;COSMIC	10.919	Loss
Other_PLK_PLK1_PLK1_ST	O60216	RAD21	P53350	PLK1	S280	G274V	274	Missense	distal	-6	no	10.971	11.242	EPSD	TCGA;ICGC;COSMIC	10.919	Up-regulation
Other_PLK_PLK1_PLK1_ST	O60216	RAD21	P53350	PLK1	S280	G274W	274	Missense	distal	-6	no	10.971	10.613	EPSD	TCGA;ICGC;COSMIC	10.919	Loss
Other_PLK_PLK1_PLK1_ST	O60216	RAD21	P53350	PLK1	S280	P275S	275	Missense	distal	-5	no	10.971	10.708	EPSD	TCGA;ICGC;COSMIC	10.919	Loss
Other_PLK_PLK1_PLK1_ST	O60216	RAD21	P53350	PLK1	T312	I311K	311	Missense	proximal	-1	no	11.659	11.067	EPSD	TCGA;ICGC;COSMIC	10.919	Down-regulation
Other_PLK_PLK1_PLK1_ST	O60216	RAD21	P53350	PLK1	T312	D310N	310	Missense	proximal	-2	no	11.659	10.416	EPSD	TCGA;ICGC;COSMIC	10.919	Loss
Other_PLK_PLK1_PLK1_ST	O60216	RAD21	P53350	PLK1	S328	K335N	335	Missense	distal	7	no	12.730	12.735	EPSD	TCGA;ICGC;COSMIC	10.919	Up-regulation
Other_PLK_PLK1_PLK1_ST	O60216	RAD21	P53350	PLK1	S328	D333H	333	Missense	distal	5	no	12.730	12.275	EPSD	TCGA;ICGC;COSMIC	10.919	Down-regulation
Other_PLK_PLK1_PLK1_ST	O60216	RAD21	P53350	PLK1	S328	D327G	327	Missense	proximal	-1	no	12.730	10.140	EPSD	TCGA;ICGC;COSMIC	10.919	Loss
Other_PLK_PLK1_PLK1_ST	O60216	RAD21	P53350	PLK1	S328	L324P	324	Missense	distal	-4	no	12.730	12.802	EPSD	TCGA;ICGC;COSMIC	10.919	Up-regulation
Other_PLK_PLK1_PLK1_ST	O60216	RAD21	P53350	PLK1	S342	K335N	335	Missense	distal	-7	no	11.135	11.290	EPSD	TCGA;ICGC;COSMIC	10.919	Up-regulation
Other_PLK_PLK1_PLK1_ST	O60216	RAD21	P53350	PLK1	S618	A622T	622	Missense	distal	4	no	11.372	11.379	EPSD	TCGA	10.919	Up-regulation
Other_PLK_PLK1_PLK1_ST	O43379	WDR62	P53350	PLK1	T55	E54K	54	Missense	proximal	-1	no	12.675	12.104	EPSD	TCGA;ICGC;COSMIC	10.919	Down-regulation
Other_PLK_PLK1_PLK1_ST	O43379	WDR62	P53350	PLK1	T55	R59L	59	Missense	distal	4	no	12.675	13.008	EPSD	TCGA;ICGC;COSMIC	10.919	Up-regulation
Other_PLK_PLK1_PLK1_ST	O43379	WDR62	P53350	PLK1	S205	S207L	207	Missense	proximal	2	no	12.062	12.134	EPSD	TCGA;ICGC;COSMIC	10.919	Up-regulation
Other_PLK_PLK1_PLK1_ST	O43379	WDR62	P53350	PLK1	S205	R200G	200	Missense	distal	-5	no	12.062	11.777	EPSD	TCGA;ICGC;COSMIC	10.919	Down-regulation
Other_PLK_PLK1_PLK1_ST	O43379	WDR62	P53350	PLK1	S207	S207L	207	Missense	central	0	yes	11.042	0.000	EPSD	TCGA;ICGC;COSMIC	10.919	Loss
Other_PLK_PLK1_PLK1_ST	O43379	WDR62	P53350	PLK1	S207	R200G	200	Missense	distal	-7	no	11.042	10.842	EPSD	TCGA;ICGC;COSMIC	10.919	Loss
Other_PLK_PLK1_PLK1_ST	O43379	WDR62	P53350	PLK1	S210	S207L	207	Missense	distal	-3	no	11.425	12.199	EPSD	TCGA;ICGC;COSMIC	10.919	Up-regulation
Other_PLK_PLK1_PLK1_ST	O43379	WDR62	P53350	PLK1	S211	S207L	207	Missense	distal	-4	no	11.779	11.586	EPSD	TCGA;ICGC;COSMIC	10.919	Down-regulation
Other_PLK_PLK1_PLK1_ST	O43379	WDR62	P53350	PLK1	S445	K452I	452	Missense	distal	7	no	13.091	13.072	EPSD	TCGA;ICGC;COSMIC	10.919	Down-regulation
Other_PLK_PLK1_PLK1_ST	O43379	WDR62	P53350	PLK1	S445	R438L	438	Missense	distal	-7	no	13.091	13.283	EPSD	TCGA;ICGC;COSMIC	10.919	Up-regulation
Other_PLK_PLK1_PLK1_ST	O43379	WDR62	P53350	PLK1	S513	S513R	513	Missense	central	0	yes	13.057	0.000	EPSD	TCGA;ICGC;COSMIC	10.919	Loss
Other_PLK_PLK1_PLK1_ST	O43379	WDR62	P53350	PLK1	S513	R512Q	512	Missense	proximal	-1	no	13.057	13.661	EPSD	TCGA;ICGC;COSMIC;GDSC;CCLE	10.919	Up-regulation
Other_PLK_PLK1_PLK1_ST	O43379	WDR62	P53350	PLK1	S513	H519Y	519	Missense	distal	6	no	13.057	13.052	EPSD	TCGA;ICGC;COSMIC	10.919	Down-regulation
Other_PLK_PLK1_PLK1_ST	O43379	WDR62	P53350	PLK1	T781	T781M	781	Missense	central	0	yes	11.155	0.000	EPSD	TCGA;ICGC;COSMIC;GDSC;CCLE	10.919	Loss
Other_PLK_PLK1_PLK1_ST	O43379	WDR62	P53350	PLK1	S791	G795R	795	Missense	distal	4	no	13.599	12.739	EPSD	TCGA;ICGC;COSMIC	10.919	Down-regulation
Other_PLK_PLK1_PLK1_ST	O43379	WDR62	P53350	PLK1	S791	E796K	796	Missense	distal	5	no	13.599	13.610	EPSD	TCGA;ICGC;COSMIC	10.919	Up-regulation
Other_PLK_PLK1_PLK1_ST	O43379	WDR62	P53350	PLK1	T798	G795R	795	Missense	distal	-3	no	12.704	12.764	EPSD	TCGA;ICGC;COSMIC	10.919	Up-regulation
Other_PLK_PLK1_PLK1_ST	O43379	WDR62	P53350	PLK1	T798	E796K	796	Missense	proximal	-2	no	12.704	9.827	EPSD	TCGA;ICGC;COSMIC	10.919	Loss
Other_PLK_PLK1_PLK1_ST	O43379	WDR62	P53350	PLK1	T798	D800N	800	Missense	proximal	2	no	12.704	12.919	EPSD	TCGA;ICGC;COSMIC	10.919	Up-regulation
Other_PLK_PLK1_PLK1_ST	O43379	WDR62	P53350	PLK1	S897	E892K	892	Missense	distal	-5	no	14.056	14.300	PhosphoSitePlus	TCGA;ICGC;COSMIC	10.919	Up-regulation
Other_PLK_PLK1_PLK1_ST	O43379	WDR62	P53350	PLK1	S935	A937T	937	Missense	proximal	2	no	11.137	10.736	EPSD	TCGA;ICGC;COSMIC	10.919	Loss
Other_PLK_PLK1_PLK1_ST	O43379	WDR62	P53350	PLK1	S987	K984M	984	Missense	distal	-3	no	12.627	12.508	EPSD	TCGA;ICGC;COSMIC	10.919	Down-regulation
Other_PLK_PLK1_PLK1_ST	O43379	WDR62	P53350	PLK1	S987	P988S	988	Missense	proximal	1	no	12.627	11.506	EPSD	TCGA;ICGC;COSMIC;GDSC;CCLE	10.919	Down-regulation
Other_PLK_PLK1_PLK1_ST	O43379	WDR62	P53350	PLK1	S987	S987N	987	Missense	central	0	yes	12.627	0.000	EPSD	TCGA;ICGC;COSMIC	10.919	Loss
Other_PLK_PLK1_PLK1_ST	O43379	WDR62	P53350	PLK1	S987	P988L	988	Missense	proximal	1	no	12.627	13.473	EPSD	TCGA;ICGC;COSMIC;GDSC;CCLE	10.919	Up-regulation
Other_PLK_PLK1_PLK1_ST	O43379	WDR62	P53350	PLK1	S992	P988S	988	Missense	distal	-4	no	11.431	11.553	EPSD	TCGA;ICGC;COSMIC;GDSC;CCLE	10.919	Up-regulation
Other_PLK_PLK1_PLK1_ST	O43379	WDR62	P53350	PLK1	S992	S987N	987	Missense	distal	-5	no	11.431	11.378	EPSD	TCGA;ICGC;COSMIC	10.919	Down-regulation
Other_PLK_PLK1_PLK1_ST	O43379	WDR62	P53350	PLK1	S992	P988L	988	Missense	distal	-4	no	11.431	11.359	EPSD	TCGA;ICGC;COSMIC;GDSC;CCLE	10.919	Down-regulation
Other_PLK_PLK1_PLK1_ST	O43379	WDR62	P53350	PLK1	S1002	S1008F	1008	Missense	distal	6	no	11.666	11.091	EPSD	TCGA;ICGC	10.919	Down-regulation
Other_PLK_PLK1_PLK1_ST	P01106	MYC	P53350	PLK1	S329	S329F	329	Missense	central	0	yes	13.063	0.000	EPSD	TCGA;ICGC;COSMIC	10.919	Loss
Other_PLK_PLK1_PLK1_ST	P01106	MYC	P53350	PLK1	S337	K341R	341	Missense	distal	4	no	11.125	10.566	EPSD	TCGA;ICGC;COSMIC	10.919	Loss
Other_PLK_PLK1_PLK1_ST	Q92994	BRF1	P53350	PLK1	S226	R224C	224	Missense	proximal	-2	no	11.268	9.095	EPSD	TCGA;COSMIC	10.919	Loss
Other_PLK_PLK1_PLK1_ST	Q92994	BRF1	P53350	PLK1	S226	L233I	233	Missense	distal	7	no	11.268	11.302	EPSD	TCGA	10.919	Up-regulation
Other_PLK_PLK1_PLK1_ST	Q92994	BRF1	P53350	PLK1	S226	R224H	224	Missense	proximal	-2	no	11.268	10.959	EPSD	TCGA;COSMIC	10.919	Down-regulation
Other_PLK_PLK1_PLK1_ST	Q92994	BRF1	P53350	PLK1	S226	H220Y	220	Missense	distal	-6	no	11.268	10.403	EPSD	TCGA;COSMIC	10.919	Loss
Other_PLK_PLK1_PLK1_ST	Q92994	BRF1	P53350	PLK1	S442	G445S	445	Missense	distal	3	no	14.257	14.254	EPSD	TCGA;COSMIC	10.919	Down-regulation
Other_PLK_PLK1_PLK1_ST	Q92994	BRF1	P53350	PLK1	S442	S435N	435	Missense	distal	-7	no	14.257	14.047	EPSD	TCGA;COSMIC	10.919	Down-regulation
Other_PLK_PLK1_PLK1_ST	Q92994	BRF1	P53350	PLK1	S450	D453H	453	Missense	distal	3	no	13.364	13.126	PhosphoSitePlus	TCGA;ICGC;COSMIC	10.919	Down-regulation
Other_PLK_PLK1_PLK1_ST	Q92994	BRF1	P53350	PLK1	S450	D453V	453	Missense	distal	3	no	13.364	13.271	PhosphoSitePlus	TCGA;COSMIC	10.919	Down-regulation
Other_PLK_PLK1_PLK1_ST	Q92994	BRF1	P53350	PLK1	S450	G445S	445	Missense	distal	-5	no	13.364	12.966	PhosphoSitePlus	TCGA;COSMIC	10.919	Down-regulation
Other_PLK_PLK1_PLK1_ST	Q92994	BRF1	P53350	PLK1	S450	D454Y	454	Missense	distal	4	no	13.364	13.119	PhosphoSitePlus	TCGA;COSMIC	10.919	Down-regulation
Other_PLK_PLK1_PLK1_ST	Q92994	BRF1	P53350	PLK1	S541	R544G	544	Missense	distal	3	no	12.393	12.520	EPSD	TCGA;ICGC;COSMIC	10.919	Up-regulation
Other_PLK_PLK1_PLK1_ST	Q92994	BRF1	P53350	PLK1	S541	R544W	544	Missense	distal	3	no	12.393	12.165	EPSD	TCGA;COSMIC	10.919	Down-regulation
Other_PLK_PLK1_PLK1_ST	Q92994	BRF1	P53350	PLK1	S541	V542M	542	Missense	proximal	1	no	12.393	13.549	EPSD	TCGA;COSMIC;CCLE	10.919	Up-regulation
Other_PLK_PLK1_PLK1_ST	Q92994	BRF1	P53350	PLK1	S564	P561L	561	Missense	distal	-3	no	9.769	10.961	EPSD	TCGA;COSMIC	10.919	Gain
Other_PLK_PLK1_PLK1_ST	P25490	YY1	P53350	PLK1	S118	E111K	111	Missense	distal	-7	no	12.737	12.433	EPSD	TCGA;ICGC;COSMIC	10.919	Down-regulation
Other_PLK_PLK1_PLK1_ST	P25490	YY1	P53350	PLK1	S247	S252L	252	Missense	distal	5	no	12.020	11.674	EPSD	TCGA;ICGC;COSMIC	10.919	Down-regulation
Other_PLK_PLK1_PLK1_ST	P25490	YY1	P53350	PLK1	S247	S247L	247	Missense	central	0	yes	12.020	0.000	EPSD	TCGA;ICGC;COSMIC	10.919	Loss
Other_PLK_PLK1_PLK1_ST	P25490	YY1	P53350	PLK1	S247	E245D	245	Missense	proximal	-2	no	12.020	12.414	EPSD	TCGA;ICGC;COSMIC	10.919	Up-regulation
Other_PLK_PLK1_PLK1_ST	P25490	YY1	P53350	PLK1	S252	S252L	252	Missense	central	0	yes	12.049	0.000	EPSD	TCGA;ICGC;COSMIC	10.919	Loss
Other_PLK_PLK1_PLK1_ST	P25490	YY1	P53350	PLK1	S252	S247L	247	Missense	distal	-5	no	12.049	12.713	EPSD	TCGA;ICGC;COSMIC	10.919	Up-regulation
Other_PLK_PLK1_PLK1_ST	P25490	YY1	P53350	PLK1	S252	E245D	245	Missense	distal	-7	no	12.049	11.760	EPSD	TCGA;ICGC;COSMIC	10.919	Down-regulation
Other_PLK_PLK1_PLK1_ST	P25490	YY1	P53350	PLK1	S311	H316R	316	Missense	distal	5	no	10.723	11.373	EPSD	TCGA;ICGC	10.919	Gain
Other_PLK_PLK1_PLK1_ST	O96017	CHEK2	P53350	PLK1	T26	S24C	24	Missense	proximal	-2	no	12.296	9.897	EPSD	TCGA;ICGC;COSMIC	10.919	Loss
Other_PLK_PLK1_PLK1_ST	O96017	CHEK2	P53350	PLK1	S52	S53F	53	Missense	proximal	1	no	9.572	12.620	EPSD	TCGA;ICGC;COSMIC	10.919	Gain
Other_PLK_PLK1_PLK1_ST	O96017	CHEK2	P53350	PLK1	T68	E70G	70	Missense	proximal	2	no	11.890	10.901	PhosphoSitePlus;EPSD	TCGA	10.919	Loss
Other_PLK_PLK1_PLK1_ST	O96017	CHEK2	P53350	PLK1	S357	E351Q	351	Missense	distal	-6	no	12.026	11.907	EPSD	TCGA;COSMIC	10.919	Down-regulation
Other_PLK_PLK1_PLK1_ST	O96017	CHEK2	P53350	PLK1	S456	L460H	460	Missense	distal	4	no	11.045	11.136	EPSD	TCGA;COSMIC	10.919	Up-regulation
Other_PLK_PLK1_PLK1_ST	O60285	NUAK1	P53350	PLK1	S455	T461M	461	Missense	distal	6	no	11.278	10.748	EPSD	TCGA;ICGC;COSMIC	10.919	Loss
Other_PLK_PLK1_PLK1_ST	O60285	NUAK1	P53350	PLK1	S455	S459L	459	Missense	distal	4	no	11.278	10.666	EPSD	TCGA;ICGC;COSMIC	10.919	Loss
Other_PLK_PLK1_PLK1_ST	O60285	NUAK1	P53350	PLK1	S455	G452E	452	Missense	distal	-3	no	11.278	10.336	EPSD	TCGA;ICGC;COSMIC	10.919	Loss
Other_PLK_PLK1_PLK1_ST	O60285	NUAK1	P53350	PLK1	S455	P451L	451	Missense	distal	-4	no	11.278	11.206	EPSD	TCGA;ICGC;COSMIC	10.919	Down-regulation
Other_PLK_PLK1_PLK1_ST	O60285	NUAK1	P53350	PLK1	S481	S488L	488	Missense	distal	7	no	13.272	13.270	EPSD	TCGA;ICGC;COSMIC;GDSC	10.919	Down-regulation
Other_PLK_PLK1_PLK1_ST	O60285	NUAK1	P53350	PLK1	S481	S476L	476	Missense	distal	-5	no	13.272	13.935	EPSD	TCGA;ICGC;COSMIC	10.919	Up-regulation
Other_PLK_PLK1_PLK1_ST	O60285	NUAK1	P53350	PLK1	S516	K522E	522	Missense	distal	6	no	11.243	11.312	EPSD	TCGA;ICGC;COSMIC	10.919	Up-regulation
Other_PLK_PLK1_PLK1_ST	O60285	NUAK1	P53350	PLK1	S516	R520Q	520	Missense	distal	4	no	11.243	11.773	EPSD	TCGA;COSMIC	10.919	Up-regulation
Other_PLK_PLK1_PLK1_ST	O60285	NUAK1	P53350	PLK1	S550	S550F	550	Missense	central	0	yes	15.347	0.000	EPSD	TCGA;ICGC;COSMIC	10.919	Loss
Other_PLK_PLK1_PLK1_ST	O60285	NUAK1	P53350	PLK1	S550	G555A	555	Missense	distal	5	no	15.347	15.731	EPSD	TCGA;ICGC;COSMIC	10.919	Up-regulation
Other_PLK_PLK1_PLK1_ST	O60285	NUAK1	P53350	PLK1	S550	G555D	555	Missense	distal	5	no	15.347	15.313	EPSD	TCGA;ICGC;COSMIC	10.919	Down-regulation
Other_PLK_PLK1_PLK1_ST	O60285	NUAK1	P53350	PLK1	S550	M545I	545	Missense	distal	-5	no	15.347	15.651	EPSD	TCGA;ICGC;COSMIC	10.919	Up-regulation
Other_PLK_PLK1_PLK1_ST	O60285	NUAK1	P53350	PLK1	S570	R567C	567	Missense	distal	-3	no	11.095	10.299	EPSD	TCGA;ICGC;COSMIC	10.919	Loss
Other_PLK_PLK1_PLK1_ST	O60285	NUAK1	P53350	PLK1	S570	S576R	576	Missense	distal	6	no	11.095	10.788	EPSD	TCGA;ICGC;COSMIC	10.919	Loss
Other_PLK_PLK1_PLK1_ST	O60285	NUAK1	P53350	PLK1	S570	R567H	567	Missense	distal	-3	no	11.095	10.423	EPSD	TCGA;ICGC;COSMIC	10.919	Loss
Other_PLK_PLK1_PLK1_ST	O60285	NUAK1	P53350	PLK1	S570	S566N	566	Missense	distal	-4	no	11.095	10.960	EPSD	TCGA;ICGC	10.919	Down-regulation
Other_PLK_PLK1_PLK1_ST	O60285	NUAK1	P53350	PLK1	S570	R563W	563	Missense	distal	-7	no	11.095	11.681	EPSD	TCGA;ICGC;COSMIC	10.919	Up-regulation
Other_PLK_PLK1_PLK1_ST	O60285	NUAK1	P53350	PLK1	S570	S566I	566	Missense	distal	-4	no	11.095	11.128	EPSD	TCGA;ICGC;COSMIC	10.919	Up-regulation
Other_PLK_PLK1_PLK1_ST	O60285	NUAK1	P53350	PLK1	S570	V577M	577	Missense	distal	7	no	11.095	11.115	EPSD	TCGA;ICGC;COSMIC;GDSC;CCLE	10.919	Up-regulation
Other_PLK_PLK1_PLK1_ST	O60285	NUAK1	P53350	PLK1	S570	D574N	574	Missense	distal	4	no	11.095	10.856	EPSD	TCGA;ICGC;COSMIC	10.919	Loss
Other_PLK_PLK1_PLK1_ST	O60285	NUAK1	P53350	PLK1	S636	R631W	631	Missense	distal	-5	no	17.165	16.932	EPSD	TCGA;ICGC;COSMIC	10.919	Down-regulation
Other_PLK_PLK1_PLK1_ST	O60285	NUAK1	P53350	PLK1	S636	M643I	643	Missense	distal	7	no	17.165	17.128	EPSD	TCGA;ICGC;COSMIC	10.919	Down-regulation
Other_PLK_PLK1_PLK1_ST	O60285	NUAK1	P53350	PLK1	S636	R631Q	631	Missense	distal	-5	no	17.165	16.425	EPSD	TCGA;ICGC;COSMIC	10.919	Down-regulation
Other_PLK_PLK1_PLK1_ST	O60285	NUAK1	P53350	PLK1	S636	D642N	642	Missense	distal	6	no	17.165	16.945	EPSD	TCGA;ICGC;COSMIC	10.919	Down-regulation
Other_PLK_PLK1_PLK1_ST	O60285	NUAK1	P53350	PLK1	S638	R631W	631	Missense	distal	-7	no	10.721	11.307	EPSD	TCGA;ICGC;COSMIC	10.919	Gain
Other_PLK_PLK1_PLK1_ST	O60285	NUAK1	P53350	PLK1	S638	M643I	643	Missense	distal	5	no	10.721	10.922	EPSD	TCGA;ICGC;COSMIC	10.919	Gain
Other_PLK_PLK1_PLK1_ST	O60285	NUAK1	P53350	PLK1	S638	R631Q	631	Missense	distal	-7	no	10.721	11.121	EPSD	TCGA;ICGC;COSMIC	10.919	Gain
Other_PLK_PLK1_PLK1_ST	Q12888	TP53BP1	P53350	PLK1	T543	E546K	546	Missense	distal	3	no	12.733	12.527	EPSD	TCGA	10.919	Down-regulation
Other_PLK_PLK1_PLK1_ST	Q12888	TP53BP1	P53350	PLK1	S552	E546K	546	Missense	distal	-6	no	12.408	11.835	EPSD	TCGA	10.919	Down-regulation
Other_PLK_PLK1_PLK1_ST	Q12888	TP53BP1	P53350	PLK1	S580	Q578H	578	Missense	proximal	-2	no	11.140	11.006	EPSD	TCGA;COSMIC	10.919	Down-regulation
Other_PLK_PLK1_PLK1_ST	Q12888	TP53BP1	P53350	PLK1	S640	S640F	640	Missense	central	0	yes	11.666	0.000	EPSD	TCGA;COSMIC	10.919	Loss
Other_PLK_PLK1_PLK1_ST	Q12888	TP53BP1	P53350	PLK1	T1082	E1078D	1078	Missense	distal	-4	no	11.631	11.447	EPSD	TCGA;COSMIC	10.919	Down-regulation
Other_PLK_PLK1_PLK1_ST	Q12888	TP53BP1	P53350	PLK1	T1273	E1271K	1271	Missense	proximal	-2	no	11.876	8.999	EPSD	TCGA;COSMIC	10.919	Loss
Other_PLK_PLK1_PLK1_ST	Q12888	TP53BP1	P53350	PLK1	S1311	S1311F	1311	Missense	central	0	yes	12.940	0.000	EPSD	TCGA;COSMIC	10.919	Loss
Other_PLK_PLK1_PLK1_ST	Q12888	TP53BP1	P53350	PLK1	S1317	S1311F	1311	Missense	distal	-6	no	11.305	10.788	EPSD	TCGA;COSMIC	10.919	Loss
Other_PLK_PLK1_PLK1_ST	Q12888	TP53BP1	P53350	PLK1	S1435	S1435P	1435	Missense	central	0	yes	14.652	0.000	EPSD	TCGA;COSMIC	10.919	Loss
Other_PLK_PLK1_PLK1_ST	P08670	VIM	P53350	PLK1	S7	S8L	8	Missense	proximal	1	no	9.170	11.137	EPSD	TCGA;ICGC;COSMIC	10.919	Gain
Other_PLK_PLK1_PLK1_ST	P08670	VIM	P53350	PLK1	S29	S22I	22	Missense	distal	-7	no	12.166	11.704	EPSD	TCGA;ICGC;COSMIC	10.919	Down-regulation
Other_PLK_PLK1_PLK1_ST	P08670	VIM	P53350	PLK1	S29	T33M	33	Missense	distal	4	no	12.166	11.410	EPSD	TCGA;ICGC;COSMIC	10.919	Down-regulation
Other_PLK_PLK1_PLK1_ST	P08670	VIM	P53350	PLK1	S51	R50H	50	Missense	proximal	-1	no	10.148	11.145	EPSD	TCGA;ICGC;COSMIC	10.919	Gain
Other_PLK_PLK1_PLK1_ST	P08670	VIM	P53350	PLK1	S83	Q81L	81	Missense	proximal	-2	no	12.080	11.533	PhosphoSitePlus;EPSD	TCGA;ICGC;COSMIC	10.919	Down-regulation
Other_PLK_PLK1_PLK1_ST	P08670	VIM	P53350	PLK1	S87	Q81L	81	Missense	distal	-6	no	14.167	13.833	EPSD	TCGA;ICGC;COSMIC	10.919	Down-regulation
Other_PLK_PLK1_PLK1_ST	P08670	VIM	P53350	PLK1	T202	Q195H	195	Missense	distal	-7	no	11.627	11.607	EPSD	TCGA;ICGC;COSMIC	10.919	Down-regulation
Other_PLK_PLK1_PLK1_ST	P08670	VIM	P53350	PLK1	S226	E221K	221	Missense	distal	-5	no	10.880	11.124	EPSD	TCGA;ICGC;COSMIC	10.919	Gain
Other_PLK_PLK1_PLK1_ST	P08670	VIM	P53350	PLK1	S226	E221Q	221	Missense	distal	-5	no	10.880	10.923	EPSD	TCGA;ICGC;COSMIC	10.919	Gain
Other_PLK_PLK1_PLK1_ST	P08670	VIM	P53350	PLK1	S226	R222L	222	Missense	distal	-4	no	10.880	11.253	EPSD	TCGA;ICGC;COSMIC	10.919	Gain
Other_PLK_PLK1_PLK1_ST	P08670	VIM	P53350	PLK1	S293	E288D	288	Missense	distal	-5	no	11.059	11.400	EPSD	TCGA	10.919	Up-regulation
Other_PLK_PLK1_PLK1_ST	P08670	VIM	P53350	PLK1	S293	A287T	287	Missense	distal	-6	no	11.059	10.991	EPSD	TCGA;ICGC;COSMIC	10.919	Down-regulation
Other_PLK_PLK1_PLK1_ST	P08670	VIM	P53350	PLK1	S293	F295S	295	Missense	proximal	2	no	11.059	11.610	EPSD	TCGA;ICGC;COSMIC	10.919	Up-regulation
Other_PLK_PLK1_PLK1_ST	P08670	VIM	P53350	PLK1	S299	A301T	301	Missense	proximal	2	no	13.360	12.959	EPSD	TCGA;ICGC	10.919	Down-regulation
Other_PLK_PLK1_PLK1_ST	P08670	VIM	P53350	PLK1	S299	R304Q	304	Missense	distal	5	no	13.360	12.564	EPSD	TCGA;ICGC;COSMIC;GDSC;CCLE	10.919	Down-regulation
Other_PLK_PLK1_PLK1_ST	P08670	VIM	P53350	PLK1	S299	F295S	295	Missense	distal	-4	no	13.360	13.678	EPSD	TCGA;ICGC;COSMIC	10.919	Up-regulation
Other_PLK_PLK1_PLK1_ST	P08670	VIM	P53350	PLK1	S325	A332S	332	Missense	distal	7	no	11.748	11.723	EPSD	TCGA;ICGC;COSMIC	10.919	Down-regulation
Other_PLK_PLK1_PLK1_ST	P08670	VIM	P53350	PLK1	S325	R320Q	320	Missense	distal	-5	no	11.748	11.009	EPSD	TCGA;ICGC;COSMIC	10.919	Down-regulation
Other_PLK_PLK1_PLK1_ST	P08670	VIM	P53350	PLK1	S325	L326F	326	Missense	proximal	1	no	11.748	12.829	EPSD	TCGA;ICGC;COSMIC	10.919	Up-regulation
Other_PLK_PLK1_PLK1_ST	P08670	VIM	P53350	PLK1	S325	S325F	325	Missense	central	0	yes	11.748	0.000	EPSD	TCGA;ICGC;COSMIC	10.919	Loss
Other_PLK_PLK1_PLK1_ST	P08670	VIM	P53350	PLK1	S325	Y319C	319	Missense	distal	-6	no	11.748	11.398	EPSD	TCGA;ICGC;COSMIC	10.919	Down-regulation
Other_PLK_PLK1_PLK1_ST	P08670	VIM	P53350	PLK1	S325	S325P	325	Missense	central	0	yes	11.748	0.000	EPSD	TCGA;ICGC;COSMIC;CCLE	10.919	Loss
Other_PLK_PLK1_PLK1_ST	P08670	VIM	P53350	PLK1	S409	E407K	407	Missense	proximal	-2	no	13.379	10.502	EPSD	TCGA;ICGC;COSMIC	10.919	Loss
Other_PLK_PLK1_PLK1_ST	P08670	VIM	P53350	PLK1	S409	E407V	407	Missense	proximal	-2	no	13.379	11.161	EPSD	TCGA;ICGC	10.919	Down-regulation
Other_PLK_PLK1_PLK1_ST	P08670	VIM	P53350	PLK1	S409	E407D	407	Missense	proximal	-2	no	13.379	13.773	EPSD	TCGA;ICGC;COSMIC	10.919	Up-regulation
Other_PLK_PLK1_PLK1_ST	P08670	VIM	P53350	PLK1	S419	S420F	420	Missense	proximal	1	no	10.414	13.462	EPSD	TCGA;ICGC;COSMIC	10.919	Gain
Other_PLK_PLK1_PLK1_ST	P08670	VIM	P53350	PLK1	S420	R424W	424	Missense	distal	4	no	10.735	11.274	EPSD	TCGA;ICGC;COSMIC	10.919	Gain
Other_PLK_PLK1_PLK1_ST	P08670	VIM	P53350	PLK1	S430	R424W	424	Missense	distal	-6	no	10.922	10.465	EPSD	TCGA;ICGC;COSMIC	10.919	Loss
Other_PLK_PLK1_PLK1_ST	P08670	VIM	P53350	PLK1	S430	D429Y	429	Missense	proximal	-1	no	10.922	10.465	EPSD	TCGA;ICGC;COSMIC	10.919	Loss
Other_PLK_PLK1_PLK1_ST	P08670	VIM	P53350	PLK1	S430	P432L	432	Missense	proximal	2	no	10.922	12.470	EPSD	TCGA;ICGC;COSMIC	10.919	Up-regulation
Other_PLK_PLK1_PLK1_ST	P08670	VIM	P53350	PLK1	S430	V434A	434	Missense	distal	4	no	10.922	11.185	EPSD	TCGA;ICGC;COSMIC	10.919	Up-regulation
Other_PLK_PLK1_PLK1_ST	P08670	VIM	P53350	PLK1	S459	E457K	457	Missense	proximal	-2	no	11.973	9.095	EPSD	TCGA;ICGC;COSMIC;CCLE	10.919	Loss
Other_PLK_PLK1_PLK1_ST	O95425	SVIL	P53350	PLK1	S66	L67I	67	Missense	proximal	1	no	13.619	13.411	EPSD	TCGA;ICGC;COSMIC	10.919	Down-regulation
Other_PLK_PLK1_PLK1_ST	O95425	SVIL	P53350	PLK1	S66	S73F	73	Missense	distal	7	no	13.619	13.689	EPSD	TCGA;ICGC;COSMIC	10.919	Up-regulation
Other_PLK_PLK1_PLK1_ST	O95425	SVIL	P53350	PLK1	S66	Q70H	70	Missense	distal	4	no	13.619	13.513	EPSD	TCGA;ICGC;COSMIC	10.919	Down-regulation
Other_PLK_PLK1_PLK1_ST	O95425	SVIL	P53350	PLK1	S66	D64E	64	Missense	proximal	-2	no	13.619	13.225	EPSD	TCGA	10.919	Down-regulation
Other_PLK_PLK1_PLK1_ST	O95425	SVIL	P53350	PLK1	S227	S228L	228	Missense	proximal	1	no	10.511	12.478	EPSD	TCGA;ICGC;COSMIC;CCLE	10.919	Gain
Other_PLK_PLK1_PLK1_ST	O95425	SVIL	P53350	PLK1	S238	R244W	244	Missense	distal	6	no	15.559	15.580	PhosphoSitePlus	TCGA;ICGC	10.919	Up-regulation
Other_PLK_PLK1_PLK1_ST	O95425	SVIL	P53350	PLK1	S315	A316P	316	Missense	proximal	1	no	13.327	14.318	EPSD	TCGA;ICGC;COSMIC	10.919	Up-regulation
Other_PLK_PLK1_PLK1_ST	O95425	SVIL	P53350	PLK1	S315	A316T	316	Missense	proximal	1	no	13.327	13.789	EPSD	TCGA;ICGC;COSMIC	10.919	Up-regulation
Other_PLK_PLK1_PLK1_ST	O95425	SVIL	P53350	PLK1	S341	Q343E	343	Missense	proximal	2	no	13.673	13.484	EPSD	TCGA;ICGC;COSMIC	10.919	Down-regulation
Other_PLK_PLK1_PLK1_ST	O95425	SVIL	P53350	PLK1	S341	A348V	348	Missense	distal	7	no	13.673	13.696	EPSD	TCGA	10.919	Up-regulation
Other_PLK_PLK1_PLK1_ST	O95425	SVIL	P53350	PLK1	S472	G478V	478	Missense	distal	6	no	10.610	10.922	EPSD	TCGA;ICGC;COSMIC	10.919	Gain
Other_PLK_PLK1_PLK1_ST	O95425	SVIL	P53350	PLK1	S538	S538L	538	Missense	central	0	yes	11.156	0.000	EPSD	TCGA;ICGC;COSMIC	10.919	Loss
Other_PLK_PLK1_PLK1_ST	O95425	SVIL	P53350	PLK1	S538	R544H	544	Missense	distal	6	no	11.156	10.940	EPSD	TCGA;ICGC	10.919	Down-regulation
Other_PLK_PLK1_PLK1_ST	O95425	SVIL	P53350	PLK1	S549	R544H	544	Missense	distal	-5	no	11.073	10.270	EPSD	TCGA;ICGC	10.919	Loss
Other_PLK_PLK1_PLK1_ST	O95425	SVIL	P53350	PLK1	S644	E647Q	647	Missense	distal	3	no	11.462	11.354	EPSD	TCGA;ICGC;COSMIC	10.919	Down-regulation
Other_PLK_PLK1_PLK1_ST	O95425	SVIL	P53350	PLK1	S644	R637Q	637	Missense	distal	-7	no	11.462	11.863	EPSD	TCGA;ICGC;COSMIC	10.919	Up-regulation
Other_PLK_PLK1_PLK1_ST	O95425	SVIL	P53350	PLK1	S644	R641H	641	Missense	distal	-3	no	11.462	10.791	EPSD	TCGA;ICGC;COSMIC;GDSC;CCLE	10.919	Loss
Other_PLK_PLK1_PLK1_ST	O95425	SVIL	P53350	PLK1	S644	Y642C	642	Missense	proximal	-2	no	11.462	7.953	EPSD	TCGA;ICGC;COSMIC	10.919	Loss
Other_PLK_PLK1_PLK1_ST	O95425	SVIL	P53350	PLK1	S644	G646V	646	Missense	proximal	2	no	11.462	13.247	EPSD	TCGA;ICGC;COSMIC	10.919	Up-regulation
Other_PLK_PLK1_PLK1_ST	O95425	SVIL	P53350	PLK1	S707	R702G	702	Missense	distal	-5	no	13.610	13.325	EPSD	TCGA;ICGC;COSMIC	10.919	Down-regulation
Other_PLK_PLK1_PLK1_ST	O95425	SVIL	P53350	PLK1	S707	V713I	713	Missense	distal	6	no	13.610	13.504	EPSD	TCGA;ICGC;COSMIC	10.919	Down-regulation
Other_PLK_PLK1_PLK1_ST	O95425	SVIL	P53350	PLK1	S707	K706T	706	Missense	proximal	-1	no	13.610	13.438	EPSD	TCGA;ICGC;COSMIC	10.919	Down-regulation
Other_PLK_PLK1_PLK1_ST	O95425	SVIL	P53350	PLK1	S707	K706N	706	Missense	proximal	-1	no	13.610	14.045	EPSD	TCGA;ICGC;COSMIC	10.919	Up-regulation
Other_PLK_PLK1_PLK1_ST	O95425	SVIL	P53350	PLK1	S734	R728C	728	Missense	distal	-6	no	14.484	13.729	EPSD	TCGA;ICGC;COSMIC;GDSC;CCLE	10.919	Down-regulation
Other_PLK_PLK1_PLK1_ST	O95425	SVIL	P53350	PLK1	S734	R729C	729	Missense	distal	-5	no	14.484	13.819	EPSD	TCGA;ICGC;COSMIC	10.919	Down-regulation
Other_PLK_PLK1_PLK1_ST	O95425	SVIL	P53350	PLK1	S811	S810F	810	Missense	proximal	-1	no	13.877	13.338	EPSD	TCGA;ICGC;COSMIC	10.919	Down-regulation
Other_PLK_PLK1_PLK1_ST	O95425	SVIL	P53350	PLK1	T852	T856K	856	Missense	distal	4	no	11.402	11.209	EPSD	TCGA;ICGC;COSMIC	10.919	Down-regulation
Other_PLK_PLK1_PLK1_ST	O95425	SVIL	P53350	PLK1	T852	M846I	846	Missense	distal	-6	no	11.402	11.589	EPSD	TCGA;ICGC;COSMIC	10.919	Up-regulation
Other_PLK_PLK1_PLK1_ST	O95425	SVIL	P53350	PLK1	T852	T856A	856	Missense	distal	4	no	11.402	11.395	EPSD	TCGA;ICGC	10.919	Down-regulation
Other_PLK_PLK1_PLK1_ST	O95425	SVIL	P53350	PLK1	T852	R849G	849	Missense	distal	-3	no	11.402	11.342	EPSD	TCGA;ICGC;COSMIC	10.919	Down-regulation
Other_PLK_PLK1_PLK1_ST	O95425	SVIL	P53350	PLK1	S905	Y909F	909	Missense	distal	4	no	11.090	10.518	EPSD	TCGA;ICGC;COSMIC	10.919	Loss
Other_PLK_PLK1_PLK1_ST	O95425	SVIL	P53350	PLK1	S905	L900F	900	Missense	distal	-5	no	11.090	10.165	EPSD	TCGA;ICGC;COSMIC	10.919	Loss
Other_PLK_PLK1_PLK1_ST	O95425	SVIL	P53350	PLK1	S918	S918L	918	Missense	central	0	yes	13.078	0.000	EPSD	TCGA;ICGC;COSMIC	10.919	Loss
Other_PLK_PLK1_PLK1_ST	O95425	SVIL	P53350	PLK1	S918	S920C	920	Missense	proximal	2	no	13.078	12.106	EPSD	TCGA;ICGC;COSMIC	10.919	Down-regulation
Other_PLK_PLK1_PLK1_ST	O95425	SVIL	P53350	PLK1	S918	R923I	923	Missense	distal	5	no	13.078	13.031	EPSD	TCGA;ICGC;COSMIC	10.919	Down-regulation
Other_PLK_PLK1_PLK1_ST	O95425	SVIL	P53350	PLK1	S920	S918L	918	Missense	proximal	-2	no	11.777	10.829	EPSD	TCGA;ICGC;COSMIC	10.919	Loss
Other_PLK_PLK1_PLK1_ST	O95425	SVIL	P53350	PLK1	S920	S920C	920	Missense	central	0	yes	11.777	0.000	EPSD	TCGA;ICGC;COSMIC	10.919	Loss
Other_PLK_PLK1_PLK1_ST	O95425	SVIL	P53350	PLK1	S920	R923I	923	Missense	distal	3	no	11.777	11.930	EPSD	TCGA;ICGC;COSMIC	10.919	Up-regulation
Other_PLK_PLK1_PLK1_ST	O95425	SVIL	P53350	PLK1	S938	P933S	933	Missense	distal	-5	no	11.444	11.182	EPSD	TCGA;ICGC	10.919	Down-regulation
Other_PLK_PLK1_PLK1_ST	O95425	SVIL	P53350	PLK1	S968	M963I	963	Missense	distal	-5	no	14.941	15.245	EPSD	TCGA;ICGC;COSMIC	10.919	Up-regulation
Other_PLK_PLK1_PLK1_ST	O95425	SVIL	P53350	PLK1	S968	A974T	974	Missense	distal	6	no	14.941	14.934	EPSD	TCGA;ICGC;COSMIC	10.919	Down-regulation
Other_PLK_PLK1_PLK1_ST	O95425	SVIL	P53350	PLK1	T1230	I1229T	1229	Missense	proximal	-1	no	11.758	10.994	EPSD	TCGA;ICGC;COSMIC	10.919	Down-regulation
Other_PLK_PLK1_PLK1_ST	O95425	SVIL	P53350	PLK1	T1230	I1236S	1236	Missense	distal	6	no	11.758	11.757	EPSD	TCGA;COSMIC	10.919	Down-regulation
Other_PLK_PLK1_PLK1_ST	O95425	SVIL	P53350	PLK1	S1314	F1308S	1308	Missense	distal	-6	no	10.894	11.411	EPSD	TCGA;COSMIC	10.919	Gain
Other_PLK_PLK1_PLK1_ST	O95425	SVIL	P53350	PLK1	S1314	F1311V	1311	Missense	distal	-3	no	10.894	11.647	EPSD	TCGA;COSMIC	10.919	Gain
Other_PLK_PLK1_PLK1_ST	O95425	SVIL	P53350	PLK1	T1379	E1372G	1372	Missense	distal	-7	no	12.068	11.432	EPSD	TCGA;ICGC;COSMIC	10.919	Down-regulation
Other_PLK_PLK1_PLK1_ST	O95425	SVIL	P53350	PLK1	T1379	V1385I	1385	Missense	distal	6	no	12.068	11.961	EPSD	TCGA;ICGC;COSMIC	10.919	Down-regulation
Other_PLK_PLK1_PLK1_ST	O95425	SVIL	P53350	PLK1	S1422	L1423M	1423	Missense	proximal	1	no	10.503	11.260	EPSD	TCGA;ICGC;COSMIC	10.919	Gain
Other_PLK_PLK1_PLK1_ST	O95425	SVIL	P53350	PLK1	S1422	R1424L	1424	Missense	proximal	2	no	10.503	11.303	EPSD	TCGA;ICGC;COSMIC	10.919	Gain
Other_PLK_PLK1_PLK1_ST	Q9UJX2	CDC23	P53350	PLK1	S21	F26L	26	Missense	distal	5	no	11.022	10.581	EPSD	TCGA;ICGC;COSMIC	10.919	Loss
Other_PLK_PLK1_PLK1_ST	Q9UJX2	CDC23	P53350	PLK1	S27	F26L	26	Missense	proximal	-1	no	14.419	14.499	EPSD	TCGA;ICGC;COSMIC	10.919	Up-regulation
Other_PLK_PLK1_PLK1_ST	Q9UJX2	CDC23	P53350	PLK1	T134	L138S	138	Missense	distal	4	no	12.873	13.485	EPSD	TCGA;ICGC	10.919	Up-regulation
Other_PLK_PLK1_PLK1_ST	Q9UJX2	CDC23	P53350	PLK1	T565	P568R	568	Missense	distal	3	no	11.542	11.396	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	10.919	Down-regulation
Other_PLK_PLK1_PLK1_ST	Q9UJX2	CDC23	P53350	PLK1	T565	E561K	561	Missense	distal	-4	no	11.542	11.159	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	10.919	Down-regulation
Other_PLK_PLK1_PLK1_ST	P30291	WEE1	P53350	PLK1	S204	S204G	204	Missense	central	0	yes	12.170	0.000	EPSD	TCGA;ICGC;COSMIC	10.919	Loss
Other_PLK_PLK1_PLK1_ST	P30291	WEE1	P53350	PLK1	S204	V206F	206	Missense	proximal	2	no	12.170	11.415	EPSD	TCGA;ICGC;COSMIC	10.919	Down-regulation
Other_PLK_PLK1_PLK1_ST	P30291	WEE1	P53350	PLK1	S242	P237A	237	Missense	distal	-5	no	11.613	11.634	EPSD	TCGA;ICGC;COSMIC	10.919	Up-regulation
Other_PLK_PLK1_PLK1_ST	P30291	WEE1	P53350	PLK1	S242	H246Y	246	Missense	distal	4	no	11.613	11.891	EPSD	TCGA;ICGC;COSMIC	10.919	Up-regulation
Other_PLK_PLK1_PLK1_ST	P30291	WEE1	P53350	PLK1	S248	H246Y	246	Missense	proximal	-2	no	9.759	11.404	EPSD	TCGA;ICGC;COSMIC	10.919	Gain
Other_PLK_PLK1_PLK1_ST	P30291	WEE1	P53350	PLK1	S270	D266G	266	Missense	distal	-4	no	12.246	11.786	EPSD	TCGA;ICGC;COSMIC	10.919	Down-regulation
Other_PLK_PLK1_PLK1_ST	P30291	WEE1	P53350	PLK1	S270	G264S	264	Missense	distal	-6	no	12.246	12.792	EPSD	TCGA;ICGC;COSMIC	10.919	Up-regulation
Other_PLK_PLK1_PLK1_ST	P30291	WEE1	P53350	PLK1	S289	M291R	291	Missense	proximal	2	no	12.095	11.370	EPSD	TCGA;ICGC;COSMIC	10.919	Down-regulation
Other_PLK_PLK1_PLK1_ST	P62826	RAN	P53350	PLK1	S135	R140Q	140	Missense	distal	5	no	11.520	10.725	PhosphoSitePlus	TCGA;COSMIC	10.919	Loss
Other_PLK_PLK1_PLK1_ST	Q9Y2Z0	SUGT1	P53350	PLK1	S345	L340V	340	Missense	distal	-5	no	12.900	12.448	EPSD	TCGA;ICGC;COSMIC	10.919	Down-regulation
Other_PLK_PLK1_PLK1_ST	Q9Y2Z0	SUGT1	P53350	PLK1	S345	K349T	349	Missense	distal	4	no	12.900	13.093	EPSD	TCGA;ICGC	10.919	Up-regulation
Other_PLK_PLK1_PLK1_ST	O15350	TP73	P53350	PLK1	T27	S34L	34	Missense	distal	7	no	13.888	13.886	PhosphoSitePlus	TCGA;ICGC;COSMIC	10.919	Down-regulation
Other_PLK_PLK1_PLK1_ST	O15350	TP73	P53350	PLK1	S48	G44V	44	Missense	distal	-4	no	14.479	15.032	EPSD	TCGA;ICGC;COSMIC	10.919	Up-regulation
Other_PLK_PLK1_PLK1_ST	O15350	TP73	P53350	PLK1	S48	T45M	45	Missense	distal	-3	no	14.479	14.354	EPSD	TCGA	10.919	Down-regulation
Other_PLK_PLK1_PLK1_ST	O15350	TP73	P53350	PLK1	S48	V51I	51	Missense	distal	3	no	14.479	14.356	EPSD	TCGA;ICGC	10.919	Down-regulation
Other_PLK_PLK1_PLK1_ST	O15350	TP73	P53350	PLK1	S48	M49T	49	Missense	proximal	1	no	14.479	12.347	EPSD	TCGA;ICGC;COSMIC	10.919	Down-regulation
Other_PLK_PLK1_PLK1_ST	O15350	TP73	P53350	PLK1	S145	P146L	146	Missense	proximal	1	no	10.570	11.416	EPSD	TCGA;ICGC;COSMIC	10.919	Gain
Other_PLK_PLK1_PLK1_ST	O15350	TP73	P53350	PLK1	T167	G172V	172	Missense	distal	5	no	11.790	11.436	EPSD	TCGA;ICGC;COSMIC	10.919	Down-regulation
Other_PLK_PLK1_PLK1_ST	O15350	TP73	P53350	PLK1	S235	G232A	232	Missense	distal	-3	no	11.099	10.848	EPSD	TCGA	10.919	Loss
Other_PLK_PLK1_PLK1_ST	O15350	TP73	P53350	PLK1	S235	V230D	230	Missense	distal	-5	no	11.099	11.131	EPSD	TCGA;ICGC;COSMIC	10.919	Up-regulation
Other_PLK_PLK1_PLK1_ST	Q9Y265	RUVBL1	P53350	PLK1	S19	A16T	16	Missense	distal	-3	no	11.064	10.918	EPSD	TCGA;ICGC;COSMIC	10.919	Loss
Other_PLK_PLK1_PLK1_ST	Q9Y265	RUVBL1	P53350	PLK1	S19	R14H	14	Missense	distal	-5	no	11.064	10.261	EPSD	TCGA;ICGC	10.919	Loss
Other_PLK_PLK1_PLK1_ST	Q9Y265	RUVBL1	P53350	PLK1	S19	G25R	25	Missense	distal	6	no	11.064	10.961	EPSD	TCGA;ICGC	10.919	Down-regulation
Other_PLK_PLK1_PLK1_ST	Q9Y265	RUVBL1	P53350	PLK1	S29	A35V	35	Missense	distal	6	no	13.246	13.071	EPSD	TCGA;ICGC;COSMIC	10.919	Down-regulation
Other_PLK_PLK1_PLK1_ST	Q9Y265	RUVBL1	P53350	PLK1	S29	G25R	25	Missense	distal	-4	no	13.246	13.333	EPSD	TCGA;ICGC	10.919	Up-regulation
Other_PLK_PLK1_PLK1_ST	Q9Y265	RUVBL1	P53350	PLK1	S322	L315R	315	Missense	distal	-7	no	11.200	11.007	EPSD	TCGA;ICGC;COSMIC	10.919	Down-regulation
Other_PLK_PLK1_PLK1_ST	Q9Y265	RUVBL1	P53350	PLK1	S322	V327I	327	Missense	distal	5	no	11.200	11.669	EPSD	TCGA;ICGC;COSMIC	10.919	Up-regulation
Other_PLK_PLK1_PLK1_ST	Q9Y265	RUVBL1	P53350	PLK1	S322	R317C	317	Missense	distal	-5	no	11.200	10.534	EPSD	TCGA;ICGC;COSMIC;GDSC;CCLE	10.919	Loss
Other_PLK_PLK1_PLK1_ST	Q9Y265	RUVBL1	P53350	PLK1	S322	A318T	318	Missense	distal	-4	no	11.200	10.798	EPSD	TCGA;ICGC;COSMIC	10.919	Loss
Other_PLK_PLK1_PLK1_ST	Q9Y265	RUVBL1	P53350	PLK1	S322	I323V	323	Missense	proximal	1	no	11.200	11.008	EPSD	TCGA;ICGC;COSMIC	10.919	Down-regulation
Other_PLK_PLK1_PLK1_ST	Q9Y265	RUVBL1	P53350	PLK1	S322	A324T	324	Missense	proximal	2	no	11.200	10.799	EPSD	TCGA;ICGC	10.919	Loss
Other_PLK_PLK1_PLK1_ST	Q9Y265	RUVBL1	P53350	PLK1	S322	H316Y	316	Missense	distal	-6	no	11.200	10.335	EPSD	TCGA;ICGC;COSMIC	10.919	Loss
Other_PLK_PLK1_PLK1_ST	Q53EZ4	CEP55	P53350	PLK1	S23	L27F	27	Missense	distal	4	no	11.342	11.140	EPSD	TCGA;ICGC;COSMIC	10.919	Down-regulation
Other_PLK_PLK1_PLK1_ST	Q53EZ4	CEP55	P53350	PLK1	S23	S23F	23	Missense	central	0	yes	11.342	0.000	EPSD	TCGA;ICGC;COSMIC	10.919	Loss
Other_PLK_PLK1_PLK1_ST	Q53EZ4	CEP55	P53350	PLK1	T25	L27F	27	Missense	proximal	2	no	11.329	10.706	EPSD	TCGA;ICGC;COSMIC	10.919	Loss
Other_PLK_PLK1_PLK1_ST	Q53EZ4	CEP55	P53350	PLK1	T25	S23F	23	Missense	proximal	-2	no	11.329	9.771	EPSD	TCGA;ICGC;COSMIC	10.919	Loss
Other_PLK_PLK1_PLK1_ST	Q53EZ4	CEP55	P53350	PLK1	T26	L27F	27	Missense	proximal	1	no	12.144	13.224	EPSD	TCGA;ICGC;COSMIC	10.919	Up-regulation
Other_PLK_PLK1_PLK1_ST	Q53EZ4	CEP55	P53350	PLK1	T26	S23F	23	Missense	distal	-3	no	12.144	11.514	EPSD	TCGA;ICGC;COSMIC	10.919	Down-regulation
Other_PLK_PLK1_PLK1_ST	Q53EZ4	CEP55	P53350	PLK1	S137	R138L	138	Missense	proximal	1	no	10.020	13.152	EPSD	TCGA;ICGC;COSMIC	10.919	Gain
Other_PLK_PLK1_PLK1_ST	Q53EZ4	CEP55	P53350	PLK1	S137	R138Q	138	Missense	proximal	1	no	10.020	11.999	EPSD	TCGA;ICGC;COSMIC	10.919	Gain
Other_PLK_PLK1_PLK1_ST	Q00613	HSF1	P53350	PLK1	S216	S221Y	221	Missense	distal	5	no	12.468	12.310	PhosphoSitePlus	TCGA;COSMIC	10.919	Down-regulation
Other_PLK_PLK1_PLK1_ST	Q00613	HSF1	P53350	PLK1	S221	S221Y	221	Missense	central	0	yes	11.236	0.000	EPSD	TCGA;COSMIC	10.919	Loss
Other_PLK_PLK1_PLK1_ST	Q00613	HSF1	P53350	PLK1	S248	S250C	250	Missense	proximal	2	no	11.043	10.071	EPSD	TCGA;COSMIC	10.919	Loss
Other_PLK_PLK1_PLK1_ST	Q00613	HSF1	P53350	PLK1	S248	A254T	254	Missense	distal	6	no	11.043	11.036	EPSD	TCGA;COSMIC;CCLE	10.919	Down-regulation
Other_PLK_PLK1_PLK1_ST	Q00613	HSF1	P53350	PLK1	S314	R317H	317	Missense	distal	3	no	11.515	11.646	EPSD	TCGA;COSMIC	10.919	Up-regulation
Other_PLK_PLK1_PLK1_ST	Q00613	HSF1	P53350	PLK1	S314	S320F	320	Missense	distal	6	no	11.515	10.939	EPSD	TCGA;COSMIC	10.919	Down-regulation
Other_PLK_PLK1_PLK1_ST	Q00613	HSF1	P53350	PLK1	S333	D332Y	332	Missense	proximal	-1	no	13.189	12.732	EPSD	TCGA;COSMIC	10.919	Down-regulation
Other_PLK_PLK1_PLK1_ST	Q00613	HSF1	P53350	PLK1	S333	E339G	339	Missense	distal	6	no	13.189	12.863	EPSD	TCGA;COSMIC	10.919	Down-regulation
Other_PLK_PLK1_PLK1_ST	Q00613	HSF1	P53350	PLK1	S333	A329T	329	Missense	distal	-4	no	13.189	12.787	EPSD	TCGA;COSMIC	10.919	Down-regulation
Other_PLK_PLK1_PLK1_ST	Q00613	HSF1	P53350	PLK1	S333	S333F	333	Missense	central	0	yes	13.189	0.000	EPSD	TCGA;COSMIC	10.919	Loss
Other_PLK_PLK1_PLK1_ST	Q00613	HSF1	P53350	PLK1	S333	P327L	327	Missense	distal	-6	no	13.189	13.478	EPSD	TCGA	10.919	Up-regulation
Other_PLK_PLK1_PLK1_ST	Q00613	HSF1	P53350	PLK1	T355	A351T	351	Missense	distal	-4	no	11.033	10.631	EPSD	TCGA;COSMIC	10.919	Loss
Other_PLK_PLK1_PLK1_ST	Q00613	HSF1	P53350	PLK1	S457	E453K	453	Missense	distal	-4	no	11.726	11.343	EPSD	TCGA;COSMIC	10.919	Down-regulation
Other_PLK_PLK1_PLK1_ST	Q00613	HSF1	P53350	PLK1	S498	E493K	493	Missense	distal	-5	no	10.883	11.127	EPSD	TCGA;ICGC;COSMIC	10.919	Gain
Other_PLK_PLK1_PLK1_ST	Q00613	HSF1	P53350	PLK1	S498	F500L	500	Missense	proximal	2	no	10.883	11.506	EPSD	TCGA;ICGC	10.919	Gain
Other_PLK_PLK1_PLK1_ST	Q00613	HSF1	P53350	PLK1	T511	A507V	507	Missense	distal	-4	no	11.246	11.106	EPSD	TCGA;ICGC;COSMIC	10.919	Down-regulation
Other_PLK_PLK1_PLK1_ST	Q00613	HSF1	P53350	PLK1	S513	A507V	507	Missense	distal	-6	no	11.967	11.728	EPSD	TCGA;ICGC;COSMIC	10.919	Down-regulation
Other_PLK_PLK1_PLK1_ST	P36507	MAP2K2	P53350	PLK1	T17	P24T	24	Missense	distal	7	no	10.988	10.946	EPSD	TCGA;ICGC;COSMIC	10.919	Down-regulation
Other_PLK_PLK1_PLK1_ST	P36507	MAP2K2	P53350	PLK1	S222	V228M	228	Missense	distal	6	no	13.658	13.296	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	10.919	Down-regulation
Other_PLK_PLK1_PLK1_ST	P36507	MAP2K2	P53350	PLK1	S226	T230M	230	Missense	distal	4	no	14.657	13.900	PhosphoSitePlus;EPSD	TCGA;ICGC;COSMIC	10.919	Down-regulation
Other_PLK_PLK1_PLK1_ST	P36507	MAP2K2	P53350	PLK1	S226	V228M	228	Missense	proximal	2	no	14.657	14.451	PhosphoSitePlus;EPSD	TCGA;ICGC;COSMIC	10.919	Down-regulation
Other_PLK_PLK1_PLK1_ST	P30626	SRI	P53350	PLK1	S87	N93D	93	Missense	distal	6	no	12.711	12.931	EPSD	TCGA;ICGC	10.919	Up-regulation
Other_PLK_PLK1_PLK1_ST	P30626	SRI	P53350	PLK1	S149	R147Q	147	Missense	proximal	-2	no	11.805	11.630	EPSD	TCGA;ICGC;COSMIC	10.919	Down-regulation
Other_PLK_PLK1_PLK1_ST	P30626	SRI	P53350	PLK1	S172	R174Q	174	Missense	proximal	2	no	12.409	12.734	EPSD	TCGA;ICGC;COSMIC	10.919	Up-regulation
Other_PLK_PLK1_PLK1_ST	Q07817	BCL2L1	P53350	PLK1	S62	A64V	64	Missense	proximal	2	no	12.434	12.877	PhosphoSitePlus	TCGA	10.919	Up-regulation
Other_PLK_PLK1_PLK1_ST	P54274	TERF1	P53350	PLK1	T24	Q27H	27	Missense	distal	3	no	11.790	11.725	EPSD	TCGA;ICGC;COSMIC	10.919	Down-regulation
Other_PLK_PLK1_PLK1_ST	P54274	TERF1	P53350	PLK1	T24	A21V	21	Missense	distal	-3	no	11.790	11.391	EPSD	TCGA;ICGC;COSMIC	10.919	Down-regulation
Other_PLK_PLK1_PLK1_ST	P54274	TERF1	P53350	PLK1	T24	T31R	31	Missense	distal	7	no	11.790	11.821	EPSD	TCGA;ICGC;COSMIC	10.919	Up-regulation
Other_PLK_PLK1_PLK1_ST	P54274	TERF1	P53350	PLK1	T24	R19G	19	Missense	distal	-5	no	11.790	11.505	EPSD	TCGA;ICGC;COSMIC	10.919	Down-regulation
Other_PLK_PLK1_PLK1_ST	P54274	TERF1	P53350	PLK1	T24	A29V	29	Missense	distal	5	no	11.790	11.052	EPSD	TCGA;ICGC;COSMIC	10.919	Down-regulation
Other_PLK_PLK1_PLK1_ST	P54274	TERF1	P53350	PLK1	S308	G310C	310	Missense	proximal	2	no	10.559	11.167	EPSD	TCGA;ICGC;COSMIC	10.919	Gain
Other_PLK_PLK1_PLK1_ST	P54274	TERF1	P53350	PLK1	T311	G310C	310	Missense	proximal	-1	no	11.638	11.575	EPSD	TCGA;ICGC;COSMIC	10.919	Down-regulation
Other_PLK_PLK1_PLK1_ST	P54274	TERF1	P53350	PLK1	S367	P369S	369	Missense	proximal	2	no	10.505	11.981	EPSD	TCGA;COSMIC	10.919	Gain
Other_PLK_PLK1_PLK1_ST	P54274	TERF1	P53350	PLK1	S435	S434F	434	Missense	proximal	-1	no	12.324	11.785	PhosphoSitePlus	TCGA;COSMIC	10.919	Down-regulation
Other_PLK_PLK1_PLK1_ST	Q2NKX8	ERCC6L	P53350	PLK1	S694	D689V	689	Missense	distal	-5	no	11.436	11.403	EPSD	TCGA;ICGC;COSMIC	10.919	Down-regulation
Other_PLK_PLK1_PLK1_ST	Q2NKX8	ERCC6L	P53350	PLK1	S694	V690M	690	Missense	distal	-4	no	11.436	11.260	EPSD	TCGA;ICGC	10.919	Down-regulation
Other_PLK_PLK1_PLK1_ST	Q2NKX8	ERCC6L	P53350	PLK1	S769	I768T	768	Missense	proximal	-1	no	11.436	10.672	EPSD	TCGA;ICGC;COSMIC	10.919	Loss
Other_PLK_PLK1_PLK1_ST	Q2NKX8	ERCC6L	P53350	PLK1	S769	T763A	763	Missense	distal	-6	no	11.436	11.503	EPSD	TCGA;ICGC;COSMIC	10.919	Up-regulation
Other_PLK_PLK1_PLK1_ST	Q2NKX8	ERCC6L	P53350	PLK1	S774	I768T	768	Missense	distal	-6	no	10.956	10.784	EPSD	TCGA;ICGC;COSMIC	10.919	Loss
Other_PLK_PLK1_PLK1_ST	Q2NKX8	ERCC6L	P53350	PLK1	S835	E833D	833	Missense	proximal	-2	no	12.949	13.343	EPSD	TCGA;ICGC	10.919	Up-regulation
Other_PLK_PLK1_PLK1_ST	Q2NKX8	ERCC6L	P53350	PLK1	T847	K845N	845	Missense	proximal	-2	no	9.385	11.414	EPSD	TCGA;ICGC;COSMIC	10.919	Gain
Other_PLK_PLK1_PLK1_ST	Q2NKX8	ERCC6L	P53350	PLK1	S913	S913Y	913	Missense	central	0	yes	11.318	0.000	EPSD	TCGA;ICGC;COSMIC	10.919	Loss
Other_PLK_PLK1_PLK1_ST	Q2NKX8	ERCC6L	P53350	PLK1	S913	E916G	916	Missense	distal	3	no	11.318	11.141	EPSD	TCGA;ICGC;COSMIC	10.919	Down-regulation
Other_PLK_PLK1_PLK1_ST	Q2NKX8	ERCC6L	P53350	PLK1	S980	V975G	975	Missense	distal	-5	no	12.651	12.839	EPSD	TCGA;ICGC;COSMIC	10.919	Up-regulation
Other_PLK_PLK1_PLK1_ST	Q2NKX8	ERCC6L	P53350	PLK1	S980	N987S	987	Missense	distal	7	no	12.651	12.596	EPSD	TCGA;ICGC;COSMIC	10.919	Down-regulation
Other_PLK_PLK1_PLK1_ST	Q2NKX8	ERCC6L	P53350	PLK1	S980	P986R	986	Missense	distal	6	no	12.651	12.200	EPSD	TCGA;ICGC;COSMIC	10.919	Down-regulation
Other_PLK_PLK1_PLK1_ST	Q2NKX8	ERCC6L	P53350	PLK1	S1036	E1031K	1031	Missense	distal	-5	no	16.554	16.797	EPSD	TCGA;ICGC;COSMIC	10.919	Up-regulation
Other_PLK_PLK1_PLK1_ST	Q2NKX8	ERCC6L	P53350	PLK1	S1077	S1081T	1081	Missense	distal	4	no	11.362	11.169	EPSD	TCGA;ICGC;COSMIC	10.919	Down-regulation
Other_PLK_PLK1_PLK1_ST	Q2NKX8	ERCC6L	P53350	PLK1	S1086	S1081T	1081	Missense	distal	-5	no	12.621	12.836	EPSD	TCGA;ICGC;COSMIC	10.919	Up-regulation
Other_PLK_PLK1_PLK1_ST	Q2NKX8	ERCC6L	P53350	PLK1	S1086	M1087V	1087	Missense	proximal	1	no	12.621	11.466	EPSD	TCGA;ICGC;COSMIC	10.919	Down-regulation
Other_PLK_PLK1_PLK1_ST	Q2NKX8	ERCC6L	P53350	PLK1	S1086	S1086Y	1086	Missense	central	0	yes	12.621	0.000	EPSD	TCGA;ICGC;COSMIC	10.919	Loss
Other_PLK_PLK1_PLK1_ST	Q2NKX8	ERCC6L	P53350	PLK1	S1086	S1092Y	1092	Missense	distal	6	no	12.621	12.094	EPSD	TCGA	10.919	Down-regulation
Other_PLK_PLK1_PLK1_ST	Q2NKX8	ERCC6L	P53350	PLK1	S1134	E1137K	1137	Missense	distal	3	no	11.020	10.813	EPSD	TCGA;ICGC;COSMIC	10.919	Loss
Other_PLK_PLK1_PLK1_ST	Q2NKX8	ERCC6L	P53350	PLK1	S1134	G1130R	1130	Missense	distal	-4	no	11.020	11.107	EPSD	TCGA;ICGC;COSMIC	10.919	Up-regulation
Other_PLK_PLK1_PLK1_ST	Q2NKX8	ERCC6L	P53350	PLK1	S1135	G1130R	1130	Missense	distal	-5	no	10.829	11.114	EPSD	TCGA;ICGC;COSMIC	10.919	Gain
Other_PLK_PLK1_PLK1_ST	Q2NKX8	ERCC6L	P53350	PLK1	S1139	E1137K	1137	Missense	proximal	-2	no	11.843	8.966	EPSD	TCGA;ICGC;COSMIC	10.919	Loss
Other_PLK_PLK1_PLK1_ST	Q2NKX8	ERCC6L	P53350	PLK1	S1139	P1146T	1146	Missense	distal	7	no	11.843	11.801	EPSD	TCGA	10.919	Down-regulation
Other_PLK_PLK1_PLK1_ST	Q2NKX8	ERCC6L	P53350	PLK1	S1139	E1143K	1143	Missense	distal	4	no	11.843	11.470	EPSD	TCGA;ICGC;COSMIC	10.919	Down-regulation
Other_PLK_PLK1_PLK1_ST	Q2NKX8	ERCC6L	P53350	PLK1	T1150	N1155K	1155	Missense	distal	5	no	10.758	11.081	EPSD	TCGA;ICGC;COSMIC	10.919	Gain
Other_PLK_PLK1_PLK1_ST	Q2NKX8	ERCC6L	P53350	PLK1	T1150	G1148E	1148	Missense	proximal	-2	no	10.758	13.686	EPSD	TCGA;ICGC;COSMIC	10.919	Gain
Other_PLK_PLK1_PLK1_ST	Q2NKX8	ERCC6L	P53350	PLK1	S1173	P1179H	1179	Missense	distal	6	no	11.507	10.840	EPSD	TCGA;ICGC;COSMIC	10.919	Loss
Other_PLK_PLK1_PLK1_ST	Q2NKX8	ERCC6L	P53350	PLK1	S1173	A1167D	1167	Missense	distal	-6	no	11.507	11.459	EPSD	TCGA;ICGC;COSMIC	10.919	Down-regulation
Other_PLK_PLK1_PLK1_ST	Q2NKX8	ERCC6L	P53350	PLK1	S1173	E1171D	1171	Missense	proximal	-2	no	11.507	11.900	EPSD	TCGA	10.919	Up-regulation
Other_PLK_PLK1_PLK1_ST	Q99708	RBBP8	P53350	PLK1	T693	D691G	691	Missense	proximal	-2	no	11.614	8.292	PhosphoSitePlus	TCGA;ICGC;COSMIC	10.919	Loss
Other_PLK_PLK1_PLK1_ST	Q06609	RAD51	P53350	PLK1	S14	D12H	12	Missense	proximal	-2	no	12.749	9.562	PhosphoSitePlus	TCGA;ICGC;COSMIC	10.919	Loss
Other_PLK_PLK1_PLK1_ST	Q06609	RAD51	P53350	PLK1	S14	E18K	18	Missense	distal	4	no	12.749	12.375	PhosphoSitePlus	TCGA;ICGC;COSMIC	10.919	Down-regulation
Other_PLK_PLK1_PLK1_ST	P46937	YAP1	P53350	PLK1	S94	F95C	95	Missense	proximal	1	no	11.592	8.779	EPSD	TCGA;ICGC	10.919	Loss
Other_PLK_PLK1_PLK1_ST	P46937	YAP1	P53350	PLK1	S127	P129S	129	Missense	proximal	2	no	10.378	11.854	EPSD	TCGA;ICGC;COSMIC	10.919	Gain
Other_PLK_PLK1_PLK1_ST	P46937	YAP1	P53350	PLK1	S131	G135E	135	Missense	distal	4	no	11.213	11.287	EPSD	TCGA;ICGC;COSMIC	10.919	Up-regulation
Other_PLK_PLK1_PLK1_ST	P46937	YAP1	P53350	PLK1	S131	P129S	129	Missense	proximal	-2	no	11.213	11.797	EPSD	TCGA;ICGC;COSMIC	10.919	Up-regulation
Other_PLK_PLK1_PLK1_ST	P46937	YAP1	P53350	PLK1	S131	S138F	138	Missense	distal	7	no	11.213	11.282	EPSD	TCGA;ICGC;COSMIC	10.919	Up-regulation
Other_PLK_PLK1_PLK1_ST	P46937	YAP1	P53350	PLK1	S131	R124P	124	Missense	distal	-7	no	11.213	11.499	EPSD	TCGA;ICGC;COSMIC	10.919	Up-regulation
Other_PLK_PLK1_PLK1_ST	P46937	YAP1	P53350	PLK1	S131	R124Q	124	Missense	distal	-7	no	11.213	11.613	EPSD	TCGA;ICGC;COSMIC	10.919	Up-regulation
Other_PLK_PLK1_PLK1_ST	P46937	YAP1	P53350	PLK1	S164	Q158H	158	Missense	distal	-6	no	12.625	12.636	EPSD	TCGA;ICGC;COSMIC	10.919	Up-regulation
Other_PLK_PLK1_PLK1_ST	P46937	YAP1	P53350	PLK1	S164	I167M	167	Missense	distal	3	no	12.625	12.306	EPSD	TCGA;ICGC	10.919	Down-regulation
Other_PLK_PLK1_PLK1_ST	P46937	YAP1	P53350	PLK1	S336	P341A	341	Missense	distal	5	no	12.334	12.513	EPSD	TCGA;ICGC;COSMIC	10.919	Up-regulation
Other_PLK_PLK1_PLK1_ST	P46937	YAP1	P53350	PLK1	S336	I333N	333	Missense	distal	-3	no	12.334	12.124	EPSD	TCGA;ICGC;COSMIC	10.919	Down-regulation
Other_PLK_PLK1_PLK1_ST	P46937	YAP1	P53350	PLK1	S336	N339H	339	Missense	distal	3	no	12.334	12.296	EPSD	TCGA;ICGC;COSMIC	10.919	Down-regulation
Other_PLK_PLK1_PLK1_ST	P46937	YAP1	P53350	PLK1	S367	G369R	369	Missense	proximal	2	no	10.144	10.997	EPSD	TCGA;ICGC	10.919	Gain
Other_PLK_PLK1_PLK1_ST	P46937	YAP1	P53350	PLK1	S393	E396D	396	Missense	distal	3	no	11.794	11.860	EPSD	TCGA;ICGC;COSMIC	10.919	Up-regulation
Other_PLK_PLK1_PLK1_ST	P46937	YAP1	P53350	PLK1	S397	E396D	396	Missense	proximal	-1	no	13.138	13.934	EPSD	TCGA;ICGC;COSMIC	10.919	Up-regulation
Other_PLK_PLK1_PLK1_ST	P46937	YAP1	P53350	PLK1	S403	E396D	396	Missense	distal	-7	no	13.822	13.532	EPSD	TCGA;ICGC;COSMIC	10.919	Down-regulation
Other_PLK_PLK1_PLK1_ST	P46937	YAP1	P53350	PLK1	S499	L501F	501	Missense	proximal	2	no	11.760	11.137	EPSD	TCGA;ICGC;COSMIC	10.919	Down-regulation
Other_PLK_PLK1_PLK1_ST	Q8IWB6	TEX14	P53350	PLK1	S437	F442L	442	Missense	distal	5	no	11.879	11.439	PhosphoSitePlus	TCGA;COSMIC	10.919	Down-regulation
Other_PLK_PLK1_PLK1_ST	Q8IWB6	TEX14	P53350	PLK1	S864	R870T	870	Missense	distal	6	no	12.771	13.354	EPSD	TCGA;COSMIC	10.919	Up-regulation
Other_PLK_PLK1_PLK1_ST	Q8IWB6	TEX14	P53350	PLK1	T873	R870T	870	Missense	distal	-3	no	11.815	11.359	EPSD	TCGA;COSMIC	10.919	Down-regulation
Other_PLK_PLK1_PLK1_ST	Q8IWB6	TEX14	P53350	PLK1	S1290	S1289Y	1289	Missense	proximal	-1	no	13.312	13.648	EPSD	TCGA;COSMIC	10.919	Up-regulation
Other_PLK_PLK1_PLK1_ST	Q8IWB6	TEX14	P53350	PLK1	S1290	R1287I	1287	Missense	distal	-3	no	13.312	12.880	EPSD	TCGA;CCLE	10.919	Down-regulation
Other_PLK_PLK1_PLK1_ST	Q8IWB6	TEX14	P53350	PLK1	S1290	A1294S	1294	Missense	distal	4	no	13.312	13.511	EPSD	TCGA;COSMIC	10.919	Up-regulation
Other_PLK_PLK1_PLK1_ST	Q8IWB6	TEX14	P53350	PLK1	S1290	S1289F	1289	Missense	proximal	-1	no	13.312	12.773	EPSD	TCGA	10.919	Down-regulation
Other_PLK_PLK1_PLK1_ST	Q8IWB6	TEX14	P53350	PLK1	S1385	E1382A	1382	Missense	distal	-3	no	14.815	15.506	EPSD	TCGA;ICGC;COSMIC	10.919	Up-regulation
Other_PLK_PLK1_PLK1_ST	Q8IWB6	TEX14	P53350	PLK1	S1385	L1387I	1387	Missense	proximal	2	no	14.815	15.164	EPSD	TCGA;ICGC	10.919	Up-regulation
Other_PLK_PLK1_PLK1_ST	Q8IWB6	TEX14	P53350	PLK1	S1385	S1389P	1389	Missense	distal	4	no	14.815	14.493	EPSD	TCGA;ICGC;COSMIC	10.919	Down-regulation
Other_PLK_PLK1_PLK1_ST	Q96T23	RSF1	P53350	PLK1	S218	R225L	225	Missense	distal	7	no	13.636	13.619	EPSD	TCGA;COSMIC	10.919	Down-regulation
Other_PLK_PLK1_PLK1_ST	Q96T23	RSF1	P53350	PLK1	S223	R225L	225	Missense	proximal	2	no	10.488	11.288	EPSD	TCGA;COSMIC	10.919	Gain
Other_PLK_PLK1_PLK1_ST	Q96T23	RSF1	P53350	PLK1	S227	R225L	225	Missense	proximal	-2	no	11.257	10.535	EPSD	TCGA;COSMIC	10.919	Loss
Other_PLK_PLK1_PLK1_ST	Q96T23	RSF1	P53350	PLK1	S314	I307S	307	Missense	distal	-7	no	10.781	11.243	EPSD	TCGA	10.919	Gain
Other_PLK_PLK1_PLK1_ST	Q96T23	RSF1	P53350	PLK1	S471	S475F	475	Missense	distal	4	no	10.932	10.118	EPSD	TCGA;COSMIC;CCLE	10.919	Loss
Other_PLK_PLK1_PLK1_ST	Q96T23	RSF1	P53350	PLK1	S471	E470Q	470	Missense	proximal	-1	no	10.932	10.603	EPSD	TCGA;COSMIC	10.919	Loss
Other_PLK_PLK1_PLK1_ST	Q96T23	RSF1	P53350	PLK1	S471	D477N	477	Missense	distal	6	no	10.932	10.711	EPSD	TCGA;COSMIC	10.919	Loss
Other_PLK_PLK1_PLK1_ST	Q96T23	RSF1	P53350	PLK1	S471	D477G	477	Missense	distal	6	no	10.932	10.456	EPSD	TCGA;COSMIC	10.919	Loss
Other_PLK_PLK1_PLK1_ST	Q96T23	RSF1	P53350	PLK1	S471	K468N	468	Missense	distal	-3	no	10.932	10.750	EPSD	TCGA	10.919	Loss
Other_PLK_PLK1_PLK1_ST	Q96T23	RSF1	P53350	PLK1	S471	D477E	477	Missense	distal	6	no	10.932	10.782	EPSD	TCGA	10.919	Loss
Other_PLK_PLK1_PLK1_ST	Q96T23	RSF1	P53350	PLK1	S473	S475F	475	Missense	proximal	2	no	11.468	10.917	EPSD	TCGA;COSMIC;CCLE	10.919	Loss
Other_PLK_PLK1_PLK1_ST	Q96T23	RSF1	P53350	PLK1	S473	E470Q	470	Missense	distal	-3	no	11.468	11.795	EPSD	TCGA;COSMIC	10.919	Up-regulation
Other_PLK_PLK1_PLK1_ST	Q96T23	RSF1	P53350	PLK1	S473	D477N	477	Missense	distal	4	no	11.468	11.230	EPSD	TCGA;COSMIC	10.919	Down-regulation
Other_PLK_PLK1_PLK1_ST	Q96T23	RSF1	P53350	PLK1	S473	D477G	477	Missense	distal	4	no	11.468	11.380	EPSD	TCGA;COSMIC	10.919	Down-regulation
Other_PLK_PLK1_PLK1_ST	Q96T23	RSF1	P53350	PLK1	S473	K468N	468	Missense	distal	-5	no	11.468	11.270	EPSD	TCGA	10.919	Down-regulation
Other_PLK_PLK1_PLK1_ST	Q96T23	RSF1	P53350	PLK1	S473	D477E	477	Missense	distal	4	no	11.468	11.454	EPSD	TCGA	10.919	Down-regulation
Other_PLK_PLK1_PLK1_ST	Q96T23	RSF1	P53350	PLK1	S489	S492F	492	Missense	distal	3	no	11.324	11.384	EPSD	TCGA;COSMIC	10.919	Up-regulation
Other_PLK_PLK1_PLK1_ST	Q96T23	RSF1	P53350	PLK1	S489	S492Y	492	Missense	distal	3	no	11.324	11.143	EPSD	TCGA;COSMIC	10.919	Down-regulation
Other_PLK_PLK1_PLK1_ST	Q96T23	RSF1	P53350	PLK1	S489	T482P	482	Missense	distal	-7	no	11.324	11.122	EPSD	TCGA;COSMIC	10.919	Down-regulation
Other_PLK_PLK1_PLK1_ST	Q96T23	RSF1	P53350	PLK1	S489	G484E	484	Missense	distal	-5	no	11.324	10.827	EPSD	TCGA;COSMIC	10.919	Loss
Other_PLK_PLK1_PLK1_ST	Q96T23	RSF1	P53350	PLK1	S492	S492F	492	Missense	central	0	yes	11.401	0.000	EPSD	TCGA;COSMIC	10.919	Loss
Other_PLK_PLK1_PLK1_ST	Q96T23	RSF1	P53350	PLK1	S492	S492Y	492	Missense	central	0	yes	11.401	0.000	EPSD	TCGA;COSMIC	10.919	Loss
Other_PLK_PLK1_PLK1_ST	Q96T23	RSF1	P53350	PLK1	T495	S492Y	492	Missense	distal	-3	no	10.576	11.045	EPSD	TCGA;COSMIC	10.919	Gain
Other_PLK_PLK1_PLK1_ST	Q96T23	RSF1	P53350	PLK1	S515	E521Q	521	Missense	distal	6	no	11.232	11.092	EPSD	TCGA;COSMIC	10.919	Down-regulation
Other_PLK_PLK1_PLK1_ST	Q96T23	RSF1	P53350	PLK1	S515	D512Y	512	Missense	distal	-3	no	11.232	11.411	EPSD	TCGA;COSMIC;CCLE	10.919	Up-regulation
Other_PLK_PLK1_PLK1_ST	Q96T23	RSF1	P53350	PLK1	S516	E521Q	521	Missense	distal	5	no	13.018	12.859	EPSD	TCGA;COSMIC	10.919	Down-regulation
Other_PLK_PLK1_PLK1_ST	Q96T23	RSF1	P53350	PLK1	S516	D512Y	512	Missense	distal	-4	no	13.018	12.526	EPSD	TCGA;COSMIC;CCLE	10.919	Down-regulation
Other_PLK_PLK1_PLK1_ST	Q96T23	RSF1	P53350	PLK1	S540	D533N	533	Missense	distal	-7	no	11.496	11.636	EPSD	TCGA;COSMIC	10.919	Up-regulation
Other_PLK_PLK1_PLK1_ST	Q96T23	RSF1	P53350	PLK1	S540	E538D	538	Missense	proximal	-2	no	11.496	11.890	EPSD	TCGA;COSMIC	10.919	Up-regulation
Other_PLK_PLK1_PLK1_ST	Q96T23	RSF1	P53350	PLK1	S540	E538K	538	Missense	proximal	-2	no	11.496	8.618	EPSD	TCGA;COSMIC	10.919	Loss
Other_PLK_PLK1_PLK1_ST	Q96T23	RSF1	P53350	PLK1	S540	E536D	536	Missense	distal	-4	no	11.496	11.312	EPSD	TCGA;COSMIC	10.919	Down-regulation
Other_PLK_PLK1_PLK1_ST	Q96T23	RSF1	P53350	PLK1	S540	P534S	534	Missense	distal	-6	no	11.496	12.119	EPSD	TCGA;COSMIC	10.919	Up-regulation
Other_PLK_PLK1_PLK1_ST	Q96T23	RSF1	P53350	PLK1	S544	D549Y	549	Missense	distal	5	no	12.136	11.830	EPSD	TCGA;COSMIC	10.919	Down-regulation
Other_PLK_PLK1_PLK1_ST	Q96T23	RSF1	P53350	PLK1	S544	E538D	538	Missense	distal	-6	no	12.136	11.933	EPSD	TCGA;COSMIC	10.919	Down-regulation
Other_PLK_PLK1_PLK1_ST	Q96T23	RSF1	P53350	PLK1	S544	L550I	550	Missense	distal	6	no	12.136	12.098	EPSD	TCGA;COSMIC	10.919	Down-regulation
Other_PLK_PLK1_PLK1_ST	Q96T23	RSF1	P53350	PLK1	S544	E538K	538	Missense	distal	-6	no	12.136	11.562	EPSD	TCGA;COSMIC	10.919	Down-regulation
Other_PLK_PLK1_PLK1_ST	Q96T23	RSF1	P53350	PLK1	S741	R742W	742	Missense	proximal	1	no	9.380	12.083	EPSD	TCGA;COSMIC	10.919	Gain
Other_PLK_PLK1_PLK1_ST	Q96T23	RSF1	P53350	PLK1	S811	E808D	808	Missense	distal	-3	no	10.644	11.103	EPSD	TCGA;COSMIC	10.919	Gain
Other_PLK_PLK1_PLK1_ST	Q96T23	RSF1	P53350	PLK1	T812	E808D	808	Missense	distal	-4	no	11.720	11.536	EPSD	TCGA;COSMIC	10.919	Down-regulation
Other_PLK_PLK1_PLK1_ST	Q96T23	RSF1	P53350	PLK1	T812	A813S	813	Missense	proximal	1	no	11.720	11.590	EPSD	TCGA	10.919	Down-regulation
Other_PLK_PLK1_PLK1_ST	Q96T23	RSF1	P53350	PLK1	T817	A813S	813	Missense	distal	-4	no	11.051	11.012	EPSD	TCGA	10.919	Down-regulation
Other_PLK_PLK1_PLK1_ST	Q96T23	RSF1	P53350	PLK1	S858	E863K	863	Missense	distal	5	no	11.865	11.876	EPSD	TCGA;COSMIC	10.919	Up-regulation
Other_PLK_PLK1_PLK1_ST	Q96T23	RSF1	P53350	PLK1	S858	S862N	862	Missense	distal	4	no	11.865	11.629	EPSD	TCGA;COSMIC	10.919	Down-regulation
Other_PLK_PLK1_PLK1_ST	Q96T23	RSF1	P53350	PLK1	S990	K996N	996	Missense	distal	6	no	13.016	13.015	EPSD	TCGA;COSMIC	10.919	Down-regulation
Other_PLK_PLK1_PLK1_ST	Q96T23	RSF1	P53350	PLK1	S990	F989L	989	Missense	proximal	-1	no	13.016	13.095	EPSD	TCGA;COSMIC	10.919	Up-regulation
Other_PLK_PLK1_PLK1_ST	Q96T23	RSF1	P53350	PLK1	S1053	R1048Q	1048	Missense	distal	-5	no	13.175	12.436	EPSD	TCGA;COSMIC	10.919	Down-regulation
Other_PLK_PLK1_PLK1_ST	Q96T23	RSF1	P53350	PLK1	S1053	S1053F	1053	Missense	central	0	yes	13.175	0.000	EPSD	TCGA;COSMIC	10.919	Loss
Other_PLK_PLK1_PLK1_ST	Q96T23	RSF1	P53350	PLK1	S1053	D1051N	1051	Missense	proximal	-2	no	13.175	11.933	EPSD	TCGA	10.919	Down-regulation
Other_PLK_PLK1_PLK1_ST	Q96T23	RSF1	P53350	PLK1	S1053	R1059C	1059	Missense	distal	6	no	13.175	12.550	EPSD	TCGA;COSMIC	10.919	Down-regulation
Other_PLK_PLK1_PLK1_ST	Q96T23	RSF1	P53350	PLK1	S1064	R1059C	1059	Missense	distal	-5	no	12.183	11.518	EPSD	TCGA;COSMIC	10.919	Down-regulation
Other_PLK_PLK1_PLK1_ST	Q96T23	RSF1	P53350	PLK1	S1096	R1089Q	1089	Missense	distal	-7	no	12.211	12.612	EPSD	TCGA;COSMIC	10.919	Up-regulation
Other_PLK_PLK1_PLK1_ST	Q96T23	RSF1	P53350	PLK1	S1139	D1140N	1140	Missense	proximal	1	no	13.314	13.120	EPSD	TCGA;COSMIC	10.919	Down-regulation
Other_PLK_PLK1_PLK1_ST	Q96T23	RSF1	P53350	PLK1	S1139	P1133L	1133	Missense	distal	-6	no	13.314	13.603	EPSD	TCGA;COSMIC;CCLE	10.919	Up-regulation
Other_PLK_PLK1_PLK1_ST	Q96T23	RSF1	P53350	PLK1	S1139	D1142G	1142	Missense	distal	3	no	13.314	13.072	EPSD	TCGA;COSMIC	10.919	Down-regulation
Other_PLK_PLK1_PLK1_ST	Q96T23	RSF1	P53350	PLK1	S1139	R1146C	1146	Missense	distal	7	no	13.314	13.367	EPSD	TCGA;COSMIC	10.919	Up-regulation
Other_PLK_PLK1_PLK1_ST	Q96T23	RSF1	P53350	PLK1	S1139	R1146H	1146	Missense	distal	7	no	13.314	13.285	EPSD	TCGA;COSMIC	10.919	Down-regulation
Other_PLK_PLK1_PLK1_ST	Q96T23	RSF1	P53350	PLK1	S1192	D1194N	1194	Missense	proximal	2	no	13.469	13.683	EPSD	TCGA;COSMIC	10.919	Up-regulation
Other_PLK_PLK1_PLK1_ST	Q96T23	RSF1	P53350	PLK1	S1196	D1194N	1194	Missense	proximal	-2	no	11.764	10.521	EPSD	TCGA;COSMIC	10.919	Loss
Other_PLK_PLK1_PLK1_ST	Q96T23	RSF1	P53350	PLK1	S1226	R1232C	1232	Missense	distal	6	no	11.104	10.479	EPSD	TCGA;CCLE	10.919	Loss
Other_PLK_PLK1_PLK1_ST	Q96T23	RSF1	P53350	PLK1	S1226	R1231Q	1231	Missense	distal	5	no	11.104	10.309	EPSD	TCGA;COSMIC	10.919	Loss
Other_PLK_PLK1_PLK1_ST	Q96T23	RSF1	P53350	PLK1	S1229	R1232C	1232	Missense	distal	3	no	11.434	11.494	EPSD	TCGA;CCLE	10.919	Up-regulation
Other_PLK_PLK1_PLK1_ST	Q96T23	RSF1	P53350	PLK1	S1229	E1235A	1235	Missense	distal	6	no	11.434	11.596	EPSD	TCGA;COSMIC	10.919	Up-regulation
Other_PLK_PLK1_PLK1_ST	Q96T23	RSF1	P53350	PLK1	S1229	R1231Q	1231	Missense	proximal	2	no	11.434	11.759	EPSD	TCGA;COSMIC	10.919	Up-regulation
Other_PLK_PLK1_PLK1_ST	Q96T23	RSF1	P53350	PLK1	S1277	R1276Q	1276	Missense	proximal	-1	no	10.317	10.921	EPSD	TCGA;COSMIC	10.919	Gain
Other_PLK_PLK1_PLK1_ST	Q96T23	RSF1	P53350	PLK1	S1282	R1276Q	1276	Missense	distal	-6	no	11.399	11.847	EPSD	TCGA;COSMIC	10.919	Up-regulation
Other_PLK_PLK1_PLK1_ST	Q96T23	RSF1	P53350	PLK1	S1282	D1279Y	1279	Missense	distal	-3	no	11.399	11.578	EPSD	TCGA;COSMIC	10.919	Up-regulation
Other_PLK_PLK1_PLK1_ST	Q96T23	RSF1	P53350	PLK1	S1310	G1316A	1316	Missense	distal	6	no	11.127	11.615	EPSD	TCGA;COSMIC	10.919	Up-regulation
Other_PLK_PLK1_PLK1_ST	Q96T23	RSF1	P53350	PLK1	S1310	A1314T	1314	Missense	distal	4	no	11.127	11.134	EPSD	TCGA;COSMIC	10.919	Up-regulation
Other_PLK_PLK1_PLK1_ST	Q96T23	RSF1	P53350	PLK1	S1364	P1369S	1369	Missense	distal	5	no	13.125	12.738	EPSD	TCGA;COSMIC	10.919	Down-regulation
Other_PLK_PLK1_PLK1_ST	Q8TD19	NEK9	P53350	PLK1	T67	G61C	61	Missense	distal	-6	no	11.239	10.582	EPSD	TCGA;ICGC;COSMIC	10.919	Loss
Other_PLK_PLK1_PLK1_ST	Q8TD19	NEK9	P53350	PLK1	S76	E82K	82	Missense	distal	6	no	12.438	12.369	EPSD	TCGA;ICGC;COSMIC	10.919	Down-regulation
Other_PLK_PLK1_PLK1_ST	Q8TD19	NEK9	P53350	PLK1	S206	S206F	206	Missense	central	0	yes	13.924	0.000	EPSD	TCGA;ICGC;COSMIC	10.919	Loss
Other_PLK_PLK1_PLK1_ST	Q8TD19	NEK9	P53350	PLK1	T662	G658S	658	Missense	distal	-4	no	12.975	13.629	EPSD	TCGA;ICGC;COSMIC;GDSC;CCLE	10.919	Up-regulation
Other_PLK_PLK1_PLK1_ST	Q8TD19	NEK9	P53350	PLK1	T662	D668N	668	Missense	distal	6	no	12.975	12.755	EPSD	TCGA;ICGC;COSMIC	10.919	Down-regulation
Other_PLK_PLK1_PLK1_ST	Q8TD19	NEK9	P53350	PLK1	S966	L969R	969	Missense	distal	3	no	12.166	12.188	EPSD	TCGA;ICGC;COSMIC	10.919	Up-regulation
Other_PLK_PLK1_PLK1_ST	Q13416	ORC2	P53350	PLK1	S81	L82F	82	Missense	proximal	1	no	10.099	11.180	EPSD	TCGA;ICGC;COSMIC	10.919	Gain
Other_PLK_PLK1_PLK1_ST	Q13416	ORC2	P53350	PLK1	S96	R100T	100	Missense	distal	4	no	11.345	12.097	EPSD	TCGA;ICGC;COSMIC	10.919	Up-regulation
Other_PLK_PLK1_PLK1_ST	Q13416	ORC2	P53350	PLK1	S96	Y95F	95	Missense	proximal	-1	no	11.345	10.470	EPSD	TCGA;ICGC;COSMIC	10.919	Loss
Other_PLK_PLK1_PLK1_ST	Q13416	ORC2	P53350	PLK1	S96	G90S	90	Missense	distal	-6	no	11.345	11.891	EPSD	TCGA;ICGC;COSMIC	10.919	Up-regulation
Other_PLK_PLK1_PLK1_ST	Q13416	ORC2	P53350	PLK1	S124	K119N	119	Missense	distal	-5	no	12.397	12.199	EPSD	TCGA;ICGC	10.919	Down-regulation
Other_PLK_PLK1_PLK1_ST	Q13416	ORC2	P53350	PLK1	S156	L159M	159	Missense	distal	3	no	13.391	13.248	EPSD	TCGA;ICGC	10.919	Down-regulation
Other_PLK_PLK1_PLK1_ST	Q13416	ORC2	P53350	PLK1	S156	P150L	150	Missense	distal	-6	no	13.391	13.680	EPSD	TCGA;ICGC;COSMIC	10.919	Up-regulation
Other_PLK_PLK1_PLK1_ST	Q13416	ORC2	P53350	PLK1	S177	S184C	184	Missense	distal	7	no	11.229	11.298	EPSD	TCGA;ICGC	10.919	Up-regulation
Other_PLK_PLK1_PLK1_ST	Q13416	ORC2	P53350	PLK1	S177	E182K	182	Missense	distal	5	no	11.229	11.240	EPSD	TCGA;ICGC;COSMIC	10.919	Up-regulation
Other_PLK_PLK1_PLK1_ST	Q13416	ORC2	P53350	PLK1	S179	S184C	184	Missense	distal	5	no	11.399	11.527	EPSD	TCGA;ICGC	10.919	Up-regulation
Other_PLK_PLK1_PLK1_ST	Q13416	ORC2	P53350	PLK1	S179	E182K	182	Missense	distal	3	no	11.399	11.193	EPSD	TCGA;ICGC;COSMIC	10.919	Down-regulation
Other_PLK_PLK1_PLK1_ST	Q13416	ORC2	P53350	PLK1	S188	E192K	192	Missense	distal	4	no	12.626	12.252	PhosphoSitePlus	TCGA;ICGC;COSMIC	10.919	Down-regulation
Other_PLK_PLK1_PLK1_ST	Q13416	ORC2	P53350	PLK1	S188	S184C	184	Missense	distal	-4	no	12.626	11.813	PhosphoSitePlus	TCGA;ICGC	10.919	Down-regulation
Other_PLK_PLK1_PLK1_ST	Q13416	ORC2	P53350	PLK1	S188	D191N	191	Missense	distal	3	no	12.626	12.426	PhosphoSitePlus	TCGA;ICGC;COSMIC	10.919	Down-regulation
Other_PLK_PLK1_PLK1_ST	Q13416	ORC2	P53350	PLK1	S188	A195T	195	Missense	distal	7	no	12.626	12.586	PhosphoSitePlus	TCGA;ICGC;COSMIC	10.919	Down-regulation
Other_PLK_PLK1_PLK1_ST	Q13416	ORC2	P53350	PLK1	S188	E182K	182	Missense	distal	-6	no	12.626	12.052	PhosphoSitePlus	TCGA;ICGC;COSMIC	10.919	Down-regulation
Other_PLK_PLK1_PLK1_ST	Q13416	ORC2	P53350	PLK1	T202	A195T	195	Missense	distal	-7	no	11.605	11.950	EPSD	TCGA;ICGC;COSMIC	10.919	Up-regulation
Other_PLK_PLK1_PLK1_ST	Q13416	ORC2	P53350	PLK1	T202	A204T	204	Missense	proximal	2	no	11.605	11.204	EPSD	TCGA;ICGC	10.919	Down-regulation
Other_PLK_PLK1_PLK1_ST	Q13416	ORC2	P53350	PLK1	S248	H247Y	247	Missense	proximal	-1	no	10.785	11.060	EPSD	TCGA;ICGC;COSMIC	10.919	Gain
Other_PLK_PLK1_PLK1_ST	Q13416	ORC2	P53350	PLK1	S248	E245K	245	Missense	distal	-3	no	10.785	11.325	EPSD	TCGA;ICGC;COSMIC	10.919	Gain
Other_PLK_PLK1_PLK1_ST	Q13416	ORC2	P53350	PLK1	S248	L253S	253	Missense	distal	5	no	10.785	11.131	EPSD	TCGA;ICGC;COSMIC	10.919	Gain
CMGC_CDK_CDK8_CDK19_ST	P46531	NOTCH1	Q9BWU1	CDK19	S900	C893S	893	Missense	distal	-7	no	1.848	1.877	EPSD	TCGA;ICGC;COSMIC	1.856	Gain
CMGC_CDK_CDK8_CDK19_ST	P46531	NOTCH1	Q9BWU1	CDK19	S1889	G1894D	1894	Missense	distal	5	no	1.850	1.915	EPSD	TCGA;ICGC;COSMIC	1.856	Gain
CMGC_CDK_CDK8_CDK19_ST	P46531	NOTCH1	Q9BWU1	CDK19	S1941	R1940H	1940	Missense	proximal	-1	no	3.600	3.531	EPSD	TCGA;ICGC;COSMIC	1.856	Down-regulation
CMGC_CDK_CDK8_CDK19_ST	P46531	NOTCH1	Q9BWU1	CDK19	S1941	R1946H	1946	Missense	distal	5	no	3.600	3.576	EPSD	TCGA;ICGC;COSMIC	1.856	Down-regulation
CMGC_CDK_CDK8_CDK19_ST	P46531	NOTCH1	Q9BWU1	CDK19	S1941	D1942V	1942	Missense	proximal	1	no	3.600	3.605	EPSD	TCGA;ICGC;COSMIC	1.856	Up-regulation
CMGC_CDK_CDK8_CDK19_ST	P46531	NOTCH1	Q9BWU1	CDK19	S1941	R1937H	1937	Missense	distal	-4	no	3.600	3.515	EPSD	TCGA;ICGC;COSMIC	1.856	Down-regulation
CMGC_CDK_CDK8_CDK19_ST	P46531	NOTCH1	Q9BWU1	CDK19	S1941	A1936T	1936	Missense	distal	-5	no	3.600	1.504	EPSD	TCGA;ICGC;COSMIC	1.856	Loss
CMGC_CDK_CDK8_CDK19_ST	P46531	NOTCH1	Q9BWU1	CDK19	S1941	L1934M	1934	Missense	distal	-7	no	3.600	3.575	EPSD	TCGA;ICGC;COSMIC	1.856	Down-regulation
CMGC_CDK_CDK8_CDK19_ST	O00303	EIF3F	Q9BWU1	CDK19	S46	P39S	39	Missense	distal	-7	no	7.128	7.233	PhosphoSitePlus;EPSD	TCGA;ICGC;COSMIC	1.856	Up-regulation
CMGC_CDK_CDK8_CDK19_ST	O00303	EIF3F	Q9BWU1	CDK19	S46	A52T	52	Missense	distal	6	no	7.128	6.984	PhosphoSitePlus;EPSD	TCGA;ICGC	1.856	Down-regulation
CMGC_CDK_CDK8_CDK19_ST	O00303	EIF3F	Q9BWU1	CDK19	S105	Y106C	106	Missense	proximal	1	no	2.988	2.973	EPSD	TCGA	1.856	Down-regulation
CMGC_CDK_CDK8_CDK19_ST	O00303	EIF3F	Q9BWU1	CDK19	S295	D301N	301	Missense	distal	6	no	2.907	2.878	EPSD	TCGA;ICGC	1.856	Down-regulation
CMGC_CDK_CDK8_CDK19_ST	Q13153	PAK1	Q9BWU1	CDK19	T109	L107F	107	Missense	proximal	-2	no	4.084	4.079	EPSD	TCGA;ICGC;COSMIC	1.856	Down-regulation
CMGC_CDK_CDK8_CDK19_ST	Q13153	PAK1	Q9BWU1	CDK19	T109	R105H	105	Missense	distal	-4	no	4.084	3.999	EPSD	TCGA;ICGC;COSMIC	1.856	Down-regulation
CMGC_CDK_CDK8_CDK19_ST	Q13153	PAK1	Q9BWU1	CDK19	S174	E177D	177	Missense	distal	3	no	7.693	7.818	PhosphoSitePlus	TCGA;ICGC;COSMIC	1.856	Up-regulation
CMGC_CDK_CDK8_CDK19_ST	Q13153	PAK1	Q9BWU1	CDK19	S174	T167S	167	Missense	distal	-7	no	7.693	7.720	PhosphoSitePlus	TCGA;ICGC;COSMIC	1.856	Up-regulation
CMGC_CDK_CDK8_CDK19_ST	Q13153	PAK1	Q9BWU1	CDK19	S223	N227S	227	Missense	distal	4	no	1.964	1.900	EPSD	TCGA;ICGC;COSMIC	1.856	Down-regulation
CMGC_CDK_CDK8_CDK19_ST	Q13153	PAK1	Q9BWU1	CDK19	S223	T229A	229	Missense	distal	6	no	1.964	2.108	EPSD	TCGA;ICGC;COSMIC	1.856	Up-regulation
CMGC_CDK_CDK8_CDK19_ST	Q13153	PAK1	Q9BWU1	CDK19	S223	T230I	230	Missense	distal	7	no	1.964	2.023	EPSD	TCGA;ICGC;COSMIC	1.856	Up-regulation
CMGC_CDK_CDK8_CDK19_ST	Q13153	PAK1	Q9BWU1	CDK19	T230	N227S	227	Missense	distal	-3	no	2.461	2.514	EPSD	TCGA;ICGC;COSMIC	1.856	Up-regulation
CMGC_CDK_CDK8_CDK19_ST	Q13153	PAK1	Q9BWU1	CDK19	T230	T229A	229	Missense	proximal	-1	no	2.461	2.590	EPSD	TCGA;ICGC;COSMIC	1.856	Up-regulation
CMGC_CDK_CDK8_CDK19_ST	Q13153	PAK1	Q9BWU1	CDK19	T230	T230I	230	Missense	central	0	yes	2.461	0.000	EPSD	TCGA;ICGC;COSMIC	1.856	Loss
CMGC_CDK_CDK8_CDK19_ST	Q13153	PAK1	Q9BWU1	CDK19	T437	E434K	434	Missense	distal	-3	no	2.751	2.565	EPSD	TCGA;ICGC;COSMIC	1.856	Down-regulation
CMGC_CDK_CDK8_CDK19_ST	Q13153	PAK1	Q9BWU1	CDK19	T437	K439E	439	Missense	proximal	2	no	2.751	2.766	EPSD	TCGA;ICGC;COSMIC	1.856	Up-regulation
CMGC_CDK_CDK5_CDK5_ST	O60331	PIP5K1C	Q00535	CDK5	S453	P454A	454	Missense	proximal	1	no	20.931	9.905	PhosphoSitePlus;EPSD	TCGA;ICGC;COSMIC	8.808	Down-regulation
CMGC_CDK_CDK5_CDK5_ST	O60331	PIP5K1C	Q00535	CDK5	S453	R459C	459	Missense	distal	6	no	20.931	20.908	PhosphoSitePlus;EPSD	TCGA;ICGC;COSMIC;CCLE	8.808	Down-regulation
CMGC_CDK_CDK5_CDK5_ST	O60331	PIP5K1C	Q00535	CDK5	S539	S541L	541	Missense	proximal	2	no	17.824	17.677	EPSD	TCGA;ICGC;COSMIC	8.808	Down-regulation
CMGC_CDK_CDK5_CDK5_ST	O60331	PIP5K1C	Q00535	CDK5	S539	S534F	534	Missense	distal	-5	no	17.824	17.495	EPSD	TCGA;ICGC;COSMIC	8.808	Down-regulation
CMGC_CDK_CDK5_CDK5_ST	O60331	PIP5K1C	Q00535	CDK5	S539	P540S	540	Missense	proximal	1	no	17.824	5.923	EPSD	TCGA;ICGC;COSMIC	8.808	Loss
CMGC_CDK_CDK5_CDK5_ST	O60331	PIP5K1C	Q00535	CDK5	S539	R538Q	538	Missense	proximal	-1	no	17.824	17.823	EPSD	TCGA;ICGC;COSMIC	8.808	Down-regulation
CMGC_CDK_CDK5_CDK5_ST	O60331	PIP5K1C	Q00535	CDK5	S539	R538W	538	Missense	proximal	-1	no	17.824	17.820	EPSD	TCGA;ICGC	8.808	Down-regulation
CMGC_CDK_CDK5_CDK5_ST	O60331	PIP5K1C	Q00535	CDK5	S650	D643N	643	Missense	distal	-7	no	19.519	19.537	EPSD;PhosphoSitePlus	TCGA;ICGC	8.808	Up-regulation
CMGC_CDK_CDK5_CDK5_ST	O60331	PIP5K1C	Q00535	CDK5	S650	E644D	644	Missense	distal	-6	no	19.519	19.509	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	8.808	Down-regulation
CMGC_CDK_CDK5_CDK5_ST	O60331	PIP5K1C	Q00535	CDK5	S650	Y654C	654	Missense	distal	4	no	19.519	19.513	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	8.808	Down-regulation
CMGC_CDK_CDK5_CDK5_ST	O60331	PIP5K1C	Q00535	CDK5	S650	H653Y	653	Missense	distal	3	no	19.519	18.351	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	8.808	Down-regulation
CMGC_CDK_CDK5_CDK5_ST	O60331	PIP5K1C	Q00535	CDK5	S650	Y649H	649	Missense	proximal	-1	no	19.519	19.522	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	8.808	Up-regulation
CMGC_CDK_CDK5_CDK5_ST	O60331	PIP5K1C	Q00535	CDK5	S650	A656V	656	Missense	distal	6	no	19.519	19.528	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC;CCLE	8.808	Up-regulation
CMGC_CDK_CDK5_CDK5_ST	O60331	PIP5K1C	Q00535	CDK5	S650	S646C	646	Missense	distal	-4	no	19.519	18.494	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	8.808	Down-regulation
CMGC_CDK_CDK5_CDK5_ST	Q07820	MCL1	Q00535	CDK5	S121	E123K	123	Missense	proximal	2	no	17.010	17.260	EPSD	TCGA;ICGC;COSMIC	8.808	Up-regulation
CMGC_CDK_CDK5_CDK5_ST	Q07820	MCL1	Q00535	CDK5	T163	S162W	162	Missense	proximal	-1	no	18.116	18.112	EPSD	TCGA;ICGC;COSMIC	8.808	Down-regulation
CMGC_CDK_CDK5_CDK5_ST	Q07820	MCL1	Q00535	CDK5	S206	T212I	212	Missense	distal	6	no	9.433	9.427	EPSD	TCGA;ICGC;COSMIC	8.808	Down-regulation
CMGC_CDK_CDK5_CDK5_ST	P49023	PXN	Q00535	CDK5	T29	E27G	27	Missense	proximal	-2	no	17.285	17.263	EPSD	TCGA	8.808	Down-regulation
CMGC_CDK_CDK5_CDK5_ST	P49023	PXN	Q00535	CDK5	S130	M134I	134	Missense	distal	4	no	18.453	18.504	EPSD	TCGA;COSMIC	8.808	Up-regulation
CMGC_CDK_CDK5_CDK5_ST	P49023	PXN	Q00535	CDK5	S130	E128K	128	Missense	proximal	-2	no	18.453	18.866	EPSD	TCGA;COSMIC	8.808	Up-regulation
CMGC_CDK_CDK5_CDK5_ST	P49023	PXN	Q00535	CDK5	S130	Q124H	124	Missense	distal	-6	no	18.453	18.445	EPSD	TCGA;COSMIC	8.808	Down-regulation
CMGC_CDK_CDK5_CDK5_ST	P49023	PXN	Q00535	CDK5	S188	S188N	188	Missense	central	0	yes	18.052	0.000	EPSD	TCGA	8.808	Loss
CMGC_CDK_CDK5_CDK5_ST	P49023	PXN	Q00535	CDK5	S230	S227F	227	Missense	distal	-3	no	17.745	17.668	EPSD	TCGA;COSMIC	8.808	Down-regulation
CMGC_CDK_CDK5_CDK5_ST	P49023	PXN	Q00535	CDK5	S230	V237A	237	Missense	distal	7	no	17.745	17.738	EPSD	TCGA	8.808	Down-regulation
CMGC_CDK_CDK5_CDK5_ST	P49023	PXN	Q00535	CDK5	S244	V248I	248	Missense	distal	4	no	18.506	18.482	EPSD;PhosphoSitePlus	TCGA;COSMIC;CCLE	8.808	Down-regulation
CMGC_CDK_CDK5_CDK5_ST	P49023	PXN	Q00535	CDK5	S244	R247H	247	Missense	distal	3	no	18.506	17.487	EPSD;PhosphoSitePlus	TCGA;COSMIC	8.808	Down-regulation
CMGC_CDK_CDK5_CDK5_ST	P49023	PXN	Q00535	CDK5	S244	V237A	237	Missense	distal	-7	no	18.506	18.471	EPSD;PhosphoSitePlus	TCGA	8.808	Down-regulation
CMGC_CDK_CDK5_CDK5_ST	P10636	MAPT	Q00535	CDK5	S46	T52I	52	Missense	distal	6	no	17.321	17.314	EPSD	TCGA;ICGC;COSMIC	8.808	Down-regulation
CMGC_CDK_CDK5_CDK5_ST	P10636	MAPT	Q00535	CDK5	S46	P47S	47	Missense	proximal	1	no	17.321	5.420	EPSD	TCGA;ICGC;COSMIC	8.808	Loss
CMGC_CDK_CDK5_CDK5_ST	P10636	MAPT	Q00535	CDK5	S46	P47L	47	Missense	proximal	1	no	17.321	5.371	EPSD	TCGA;ICGC;COSMIC	8.808	Loss
CMGC_CDK_CDK5_CDK5_ST	P10636	MAPT	Q00535	CDK5	S46	G42C	42	Missense	distal	-4	no	17.321	17.138	EPSD	TCGA;ICGC;COSMIC	8.808	Down-regulation
CMGC_CDK_CDK5_CDK5_ST	P10636	MAPT	Q00535	CDK5	T50	D54E	54	Missense	distal	4	no	17.042	17.050	EPSD	TCGA;ICGC;COSMIC	8.808	Up-regulation
CMGC_CDK_CDK5_CDK5_ST	P10636	MAPT	Q00535	CDK5	T50	T52I	52	Missense	proximal	2	no	17.042	16.947	EPSD	TCGA;ICGC;COSMIC	8.808	Down-regulation
CMGC_CDK_CDK5_CDK5_ST	P10636	MAPT	Q00535	CDK5	T50	P47S	47	Missense	distal	-3	no	17.042	17.036	EPSD	TCGA;ICGC;COSMIC	8.808	Down-regulation
CMGC_CDK_CDK5_CDK5_ST	P10636	MAPT	Q00535	CDK5	T50	P47L	47	Missense	distal	-3	no	17.042	16.981	EPSD	TCGA;ICGC;COSMIC	8.808	Down-regulation
CMGC_CDK_CDK5_CDK5_ST	P10636	MAPT	Q00535	CDK5	T50	G55R	55	Missense	distal	5	no	17.042	17.208	EPSD	TCGA;ICGC;COSMIC	8.808	Up-regulation
CMGC_CDK_CDK5_CDK5_ST	P10636	MAPT	Q00535	CDK5	S64	G60S	60	Missense	distal	-4	no	8.353	9.194	EPSD	TCGA;ICGC;COSMIC	8.808	Gain
CMGC_CDK_CDK5_CDK5_ST	P10636	MAPT	Q00535	CDK5	T69	A72V	72	Missense	distal	3	no	17.225	17.477	EPSD	TCGA;ICGC;COSMIC	8.808	Up-regulation
CMGC_CDK_CDK5_CDK5_ST	P10636	MAPT	Q00535	CDK5	T69	A66S	66	Missense	distal	-3	no	17.225	17.272	EPSD	TCGA;ICGC;COSMIC	8.808	Up-regulation
CMGC_CDK_CDK5_CDK5_ST	P10636	MAPT	Q00535	CDK5	T111	E117K	117	Missense	distal	6	no	15.796	15.815	EPSD	TCGA;ICGC;COSMIC	8.808	Up-regulation
CMGC_CDK_CDK5_CDK5_ST	P10636	MAPT	Q00535	CDK5	T111	A118V	118	Missense	distal	7	no	15.796	15.804	EPSD	TCGA;ICGC;COSMIC	8.808	Up-regulation
CMGC_CDK_CDK5_CDK5_ST	P10636	MAPT	Q00535	CDK5	S228	S232Y	232	Missense	distal	4	no	17.027	16.942	EPSD	TCGA;ICGC;COSMIC	8.808	Down-regulation
CMGC_CDK_CDK5_CDK5_ST	P10636	MAPT	Q00535	CDK5	S228	D223Y	223	Missense	distal	-5	no	17.027	16.943	EPSD	TCGA;ICGC;COSMIC	8.808	Down-regulation
CMGC_CDK_CDK5_CDK5_ST	P10636	MAPT	Q00535	CDK5	S228	S227F	227	Missense	proximal	-1	no	17.027	17.019	EPSD	TCGA;ICGC;COSMIC	8.808	Down-regulation
CMGC_CDK_CDK5_CDK5_ST	P10636	MAPT	Q00535	CDK5	S228	P234L	234	Missense	distal	6	no	17.027	17.013	EPSD	TCGA;ICGC;COSMIC	8.808	Down-regulation
CMGC_CDK_CDK5_CDK5_ST	P10636	MAPT	Q00535	CDK5	S232	S232Y	232	Missense	central	0	yes	18.084	0.000	EPSD	TCGA;ICGC;COSMIC	8.808	Loss
CMGC_CDK_CDK5_CDK5_ST	P10636	MAPT	Q00535	CDK5	S232	S227F	227	Missense	distal	-5	no	18.084	17.754	EPSD	TCGA;ICGC;COSMIC	8.808	Down-regulation
CMGC_CDK_CDK5_CDK5_ST	P10636	MAPT	Q00535	CDK5	S232	P234L	234	Missense	proximal	2	no	18.084	17.918	EPSD	TCGA;ICGC;COSMIC	8.808	Down-regulation
CMGC_CDK_CDK5_CDK5_ST	P10636	MAPT	Q00535	CDK5	S238	S232Y	232	Missense	distal	-6	no	18.116	17.983	EPSD	TCGA;ICGC;COSMIC	8.808	Down-regulation
CMGC_CDK_CDK5_CDK5_ST	P10636	MAPT	Q00535	CDK5	S238	A240T	240	Missense	proximal	2	no	18.116	18.235	EPSD	TCGA;ICGC;COSMIC	8.808	Up-regulation
CMGC_CDK_CDK5_CDK5_ST	P10636	MAPT	Q00535	CDK5	S238	P234L	234	Missense	distal	-4	no	18.116	17.643	EPSD	TCGA;ICGC;COSMIC	8.808	Down-regulation
CMGC_CDK_CDK5_CDK5_ST	P10636	MAPT	Q00535	CDK5	S238	R244Q	244	Missense	distal	6	no	18.116	18.105	EPSD	TCGA;ICGC;COSMIC	8.808	Down-regulation
CMGC_CDK_CDK5_CDK5_ST	P10636	MAPT	Q00535	CDK5	S388	G387R	387	Missense	proximal	-1	no	8.857	8.861	EPSD	TCGA;COSMIC	8.808	Up-regulation
CMGC_CDK_CDK5_CDK5_ST	P10636	MAPT	Q00535	CDK5	S411	P415L	415	Missense	distal	4	no	17.541	17.460	EPSD	TCGA;ICGC;COSMIC	8.808	Down-regulation
CMGC_CDK_CDK5_CDK5_ST	P10636	MAPT	Q00535	CDK5	T416	P415L	415	Missense	proximal	-1	no	16.940	16.935	EPSD	TCGA;ICGC;COSMIC	8.808	Down-regulation
CMGC_CDK_CDK5_CDK5_ST	P10636	MAPT	Q00535	CDK5	S428	A430S	430	Missense	proximal	2	no	17.304	17.398	EPSD	TCGA;ICGC;COSMIC	8.808	Up-regulation
CMGC_CDK_CDK5_CDK5_ST	P10636	MAPT	Q00535	CDK5	S428	V431L	431	Missense	distal	3	no	17.304	16.225	EPSD	TCGA;ICGC;COSMIC	8.808	Down-regulation
CMGC_CDK_CDK5_CDK5_ST	P10636	MAPT	Q00535	CDK5	S428	A430V	430	Missense	proximal	2	no	17.304	17.385	EPSD	TCGA;ICGC;COSMIC	8.808	Up-regulation
CMGC_CDK_CDK5_CDK5_ST	P10636	MAPT	Q00535	CDK5	S438	P436T	436	Missense	proximal	-2	no	17.434	17.295	EPSD	TCGA;ICGC;COSMIC	8.808	Down-regulation
CMGC_CDK_CDK5_CDK5_ST	P10636	MAPT	Q00535	CDK5	S438	P436L	436	Missense	proximal	-2	no	17.434	17.020	EPSD	TCGA;ICGC;COSMIC	8.808	Down-regulation
CMGC_CDK_CDK5_CDK5_ST	P10636	MAPT	Q00535	CDK5	S438	K440E	440	Missense	proximal	2	no	17.434	17.184	EPSD	TCGA;ICGC;COSMIC	8.808	Down-regulation
CMGC_CDK_CDK5_CDK5_ST	P10636	MAPT	Q00535	CDK5	S438	S443F	443	Missense	distal	5	no	17.434	17.195	EPSD	TCGA;ICGC;COSMIC	8.808	Down-regulation
CMGC_CDK_CDK5_CDK5_ST	P10636	MAPT	Q00535	CDK5	S438	V431L	431	Missense	distal	-7	no	17.434	17.396	EPSD	TCGA;ICGC;COSMIC	8.808	Down-regulation
CMGC_CDK_CDK5_CDK5_ST	P10636	MAPT	Q00535	CDK5	S438	S444F	444	Missense	distal	6	no	17.434	17.415	EPSD	TCGA;ICGC	8.808	Down-regulation
CMGC_CDK_CDK5_CDK5_ST	P10636	MAPT	Q00535	CDK5	S447	K440E	440	Missense	distal	-7	no	9.502	9.439	EPSD	TCGA;ICGC;COSMIC	8.808	Down-regulation
CMGC_CDK_CDK5_CDK5_ST	P10636	MAPT	Q00535	CDK5	S447	S452C	452	Missense	distal	5	no	9.502	9.309	EPSD	TCGA;ICGC;COSMIC	8.808	Down-regulation
CMGC_CDK_CDK5_CDK5_ST	P10636	MAPT	Q00535	CDK5	S447	S443F	443	Missense	distal	-4	no	9.502	8.341	EPSD	TCGA;ICGC;COSMIC	8.808	Loss
CMGC_CDK_CDK5_CDK5_ST	P10636	MAPT	Q00535	CDK5	S447	S444F	444	Missense	distal	-3	no	9.502	9.425	EPSD	TCGA;ICGC	8.808	Down-regulation
CMGC_CDK_CDK5_CDK5_ST	P10636	MAPT	Q00535	CDK5	S447	S452Y	452	Missense	distal	5	no	9.502	9.325	EPSD	TCGA;ICGC;COSMIC	8.808	Down-regulation
CMGC_CDK_CDK5_CDK5_ST	P10636	MAPT	Q00535	CDK5	T470	R472Q	472	Missense	proximal	2	no	16.586	16.446	EPSD	TCGA	8.808	Down-regulation
CMGC_CDK_CDK5_CDK5_ST	P10636	MAPT	Q00535	CDK5	T470	R472W	472	Missense	proximal	2	no	16.586	16.394	EPSD	TCGA;COSMIC	8.808	Down-regulation
CMGC_CDK_CDK5_CDK5_ST	P10636	MAPT	Q00535	CDK5	T492	A485T	485	Missense	distal	-7	no	17.424	17.464	EPSD	TCGA;COSMIC;GDSC;CCLE	8.808	Up-regulation
CMGC_CDK_CDK5_CDK5_ST	P10636	MAPT	Q00535	CDK5	T492	P493Q	493	Missense	proximal	1	no	17.424	8.448	EPSD	TCGA;COSMIC	8.808	Loss
CMGC_CDK_CDK5_CDK5_ST	P10636	MAPT	Q00535	CDK5	T498	P493Q	493	Missense	distal	-5	no	17.938	17.880	EPSD	TCGA;COSMIC	8.808	Down-regulation
CMGC_CDK_CDK5_CDK5_ST	P42858	HTT	Q00535	CDK5	S263	R267W	267	Missense	distal	4	no	17.729	17.657	EPSD	TCGA;ICGC;COSMIC	8.808	Down-regulation
CMGC_CDK_CDK5_CDK5_ST	P42858	HTT	Q00535	CDK5	S263	R267Q	267	Missense	distal	4	no	17.729	17.682	EPSD	TCGA;ICGC;COSMIC	8.808	Down-regulation
CMGC_CDK_CDK5_CDK5_ST	P42858	HTT	Q00535	CDK5	S263	A270V	270	Missense	distal	7	no	17.729	17.736	EPSD	TCGA;ICGC;COSMIC	8.808	Up-regulation
CMGC_CDK_CDK5_CDK5_ST	P42858	HTT	Q00535	CDK5	T486	P487L	487	Missense	proximal	1	no	17.017	5.067	EPSD	TCGA;ICGC;COSMIC	8.808	Loss
CMGC_CDK_CDK5_CDK5_ST	P42858	HTT	Q00535	CDK5	S643	D645Y	645	Missense	proximal	2	no	9.018	8.973	EPSD	TCGA;ICGC;COSMIC	8.808	Down-regulation
CMGC_CDK_CDK5_CDK5_ST	P42858	HTT	Q00535	CDK5	S1199	Q1193K	1193	Missense	distal	-6	no	20.034	20.128	PhosphoSitePlus;EPSD	TCGA;ICGC;COSMIC	8.808	Up-regulation
CMGC_CDK_CDK5_CDK5_ST	P42858	HTT	Q00535	CDK5	S1199	L1198S	1198	Missense	proximal	-1	no	20.034	20.040	PhosphoSitePlus;EPSD	TCGA;ICGC;COSMIC	8.808	Up-regulation
CMGC_CDK_CDK5_CDK5_ST	P42858	HTT	Q00535	CDK5	S1199	P1200L	1200	Missense	proximal	1	no	20.034	8.085	PhosphoSitePlus;EPSD	TCGA;ICGC;COSMIC	8.808	Loss
CMGC_CDK_CDK5_CDK5_ST	P42858	HTT	Q00535	CDK5	T1220	S1224F	1224	Missense	distal	4	no	9.660	9.548	EPSD	TCGA;ICGC;COSMIC	8.808	Down-regulation
CMGC_CDK_CDK5_CDK5_ST	P42858	HTT	Q00535	CDK5	T1220	S1224T	1224	Missense	distal	4	no	9.660	9.658	EPSD	TCGA;ICGC;COSMIC	8.808	Down-regulation
CMGC_CDK_CDK5_CDK5_ST	P42858	HTT	Q00535	CDK5	S2094	V2088M	2088	Missense	distal	-6	no	19.112	19.008	EPSD	TCGA;ICGC;COSMIC;GDSC;CCLE	8.808	Down-regulation
CMGC_CDK_CDK5_CDK5_ST	P42858	HTT	Q00535	CDK5	S2094	L2090V	2090	Missense	distal	-4	no	19.112	19.449	EPSD	TCGA;ICGC;COSMIC	8.808	Up-regulation
CMGC_CDK_CDK5_CDK5_ST	P42858	HTT	Q00535	CDK5	S2094	D2098N	2098	Missense	distal	4	no	19.112	19.142	EPSD	TCGA;ICGC;COSMIC	8.808	Up-regulation
CMGC_CDK_CDK5_CDK5_ST	P42858	HTT	Q00535	CDK5	S2328	E2324K	2324	Missense	distal	-4	no	18.870	19.372	EPSD	TCGA;ICGC;COSMIC	8.808	Up-regulation
CMGC_CDK_CDK5_CDK5_ST	P42858	HTT	Q00535	CDK5	S2421	V2415M	2415	Missense	distal	-6	no	18.344	18.240	EPSD	TCGA;ICGC;COSMIC	8.808	Down-regulation
CMGC_CDK_CDK5_CDK5_ST	P42858	HTT	Q00535	CDK5	S2421	G2425E	2425	Missense	distal	4	no	18.344	18.342	EPSD	TCGA;ICGC;COSMIC	8.808	Down-regulation
CMGC_CDK_CDK5_CDK5_ST	P42858	HTT	Q00535	CDK5	S2584	A2586S	2586	Missense	proximal	2	no	18.284	18.378	EPSD	TCGA;ICGC;COSMIC	8.808	Up-regulation
CMGC_CDK_CDK5_CDK5_ST	P42858	HTT	Q00535	CDK5	S2584	P2579S	2579	Missense	distal	-5	no	18.284	18.306	EPSD	TCGA;ICGC;COSMIC	8.808	Up-regulation
CMGC_CDK_CDK5_CDK5_ST	P42858	HTT	Q00535	CDK5	S2584	P2585L	2585	Missense	proximal	1	no	18.284	6.334	EPSD	TCGA	8.808	Loss
CMGC_CDK_CDK5_CDK5_ST	P42858	HTT	Q00535	CDK5	S2651	P2647S	2647	Missense	distal	-4	no	18.695	19.041	EPSD	TCGA;ICGC;COSMIC	8.808	Up-regulation
CMGC_CDK_CDK5_CDK5_ST	P42858	HTT	Q00535	CDK5	S2651	T2654M	2654	Missense	distal	3	no	18.695	17.197	EPSD	TCGA;ICGC;COSMIC	8.808	Down-regulation
CMGC_CDK_CDK5_CDK5_ST	P42858	HTT	Q00535	CDK5	S2655	T2654M	2654	Missense	proximal	-1	no	18.601	18.595	EPSD	TCGA;ICGC;COSMIC	8.808	Down-regulation
CMGC_CDK_CDK5_CDK5_ST	P42858	HTT	Q00535	CDK5	S2659	T2654M	2654	Missense	distal	-5	no	10.320	10.063	EPSD	TCGA;ICGC;COSMIC	8.808	Down-regulation
CMGC_CDK_CDK5_CDK5_ST	P04150	NR3C1	Q00535	CDK5	T8	P9H	9	Missense	proximal	1	no	20.388	1.876	EPSD	TCGA;COSMIC	8.808	Loss
CMGC_CDK_CDK5_CDK5_ST	P04150	NR3C1	Q00535	CDK5	S45	A51T	51	Missense	distal	6	no	16.971	16.983	EPSD	TCGA;ICGC;COSMIC	8.808	Up-regulation
CMGC_CDK_CDK5_CDK5_ST	P04150	NR3C1	Q00535	CDK5	S45	S42Y	42	Missense	distal	-3	no	16.971	16.914	EPSD	TCGA;ICGC;COSMIC	8.808	Down-regulation
CMGC_CDK_CDK5_CDK5_ST	P04150	NR3C1	Q00535	CDK5	S52	R59Q	59	Missense	distal	7	no	8.918	8.912	EPSD	TCGA;ICGC;COSMIC	8.808	Down-regulation
CMGC_CDK_CDK5_CDK5_ST	P04150	NR3C1	Q00535	CDK5	S52	Q53E	53	Missense	proximal	1	no	8.918	-4.317	EPSD	TCGA;ICGC;COSMIC	8.808	Loss
CMGC_CDK_CDK5_CDK5_ST	P04150	NR3C1	Q00535	CDK5	S52	A51T	51	Missense	proximal	-1	no	8.918	8.923	EPSD	TCGA;ICGC;COSMIC	8.808	Up-regulation
CMGC_CDK_CDK5_CDK5_ST	P04150	NR3C1	Q00535	CDK5	S54	R59Q	59	Missense	distal	5	no	9.403	9.278	EPSD	TCGA;ICGC;COSMIC	8.808	Down-regulation
CMGC_CDK_CDK5_CDK5_ST	P04150	NR3C1	Q00535	CDK5	S54	Q53E	53	Missense	proximal	-1	no	9.403	9.402	EPSD	TCGA;ICGC;COSMIC	8.808	Down-regulation
CMGC_CDK_CDK5_CDK5_ST	P04150	NR3C1	Q00535	CDK5	S54	R60T	60	Missense	distal	6	no	9.403	9.396	EPSD	TCGA;ICGC;COSMIC;CCLE	8.808	Down-regulation
CMGC_CDK_CDK5_CDK5_ST	P04150	NR3C1	Q00535	CDK5	S54	A51T	51	Missense	distal	-3	no	9.403	9.448	EPSD	TCGA;ICGC;COSMIC	8.808	Up-regulation
CMGC_CDK_CDK5_CDK5_ST	P04150	NR3C1	Q00535	CDK5	S211	P212H	212	Missense	proximal	1	no	19.649	1.137	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	8.808	Loss
CMGC_CDK_CDK5_CDK5_ST	P04150	NR3C1	Q00535	CDK5	S226	N222T	222	Missense	distal	-4	no	16.746	16.757	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	8.808	Up-regulation
CMGC_CDK_CDK5_CDK5_ST	P04150	NR3C1	Q00535	CDK5	S226	A229V	229	Missense	distal	3	no	16.746	16.998	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	8.808	Up-regulation
CMGC_CDK_CDK5_CDK5_ST	P04150	NR3C1	Q00535	CDK5	S226	G230R	230	Missense	distal	4	no	16.746	16.814	EPSD;PhosphoSitePlus	TCGA;ICGC	8.808	Up-regulation
CMGC_CDK_CDK5_CDK5_ST	P04150	NR3C1	Q00535	CDK5	S226	I219L	219	Missense	distal	-7	no	16.746	16.724	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	8.808	Down-regulation
CMGC_CDK_CDK5_CDK5_ST	P04150	NR3C1	Q00535	CDK5	T288	P289S	289	Missense	proximal	1	no	16.898	4.997	EPSD	TCGA;ICGC;COSMIC	8.808	Loss
CMGC_CDK_CDK5_CDK5_ST	P04150	NR3C1	Q00535	CDK5	S395	S395I	395	Missense	central	0	yes	16.926	0.000	EPSD	TCGA;ICGC	8.808	Loss
CMGC_CDK_CDK5_CDK5_ST	P04150	NR3C1	Q00535	CDK5	S404	S404Y	404	Missense	central	0	yes	18.779	0.000	EPSD	TCGA;ICGC	8.808	Loss
CMGC_CDK_CDK5_CDK5_ST	P04150	NR3C1	Q00535	CDK5	S410	S404Y	404	Missense	distal	-6	no	9.188	9.055	EPSD	TCGA;ICGC	8.808	Down-regulation
CMGC_CDK_CDK5_CDK5_ST	P04150	NR3C1	Q00535	CDK5	S410	P416Q	416	Missense	distal	6	no	9.188	9.185	EPSD	TCGA;ICGC;COSMIC	8.808	Down-regulation
CMGC_CDK_CDK5_CDK5_ST	Q8NEB9	PIK3C3	Q00535	CDK5	T159	S164I	164	Missense	distal	5	no	19.273	19.183	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	8.808	Down-regulation
CMGC_CDK_CDK5_CDK5_ST	Q8NEB9	PIK3C3	Q00535	CDK5	S244	P245L	245	Missense	proximal	1	no	16.661	4.712	EPSD	TCGA;COSMIC	8.808	Loss
CMGC_CDK_CDK5_CDK5_ST	Q8NEB9	PIK3C3	Q00535	CDK5	S244	E251K	251	Missense	distal	7	no	16.661	16.677	EPSD	TCGA;COSMIC	8.808	Up-regulation
CMGC_CDK_CDK5_CDK5_ST	Q8NEB9	PIK3C3	Q00535	CDK5	S244	D239E	239	Missense	distal	-5	no	16.661	16.652	EPSD	TCGA	8.808	Down-regulation
CMGC_CDK_CDK5_CDK5_ST	Q8NEB9	PIK3C3	Q00535	CDK5	S448	S443F	443	Missense	distal	-5	no	17.073	16.744	EPSD	TCGA;ICGC;COSMIC	8.808	Down-regulation
CMGC_CDK_CDK5_CDK5_ST	Q8NEB9	PIK3C3	Q00535	CDK5	S448	S442I	442	Missense	distal	-6	no	17.073	17.001	EPSD	TCGA;ICGC;COSMIC	8.808	Down-regulation
CMGC_CDK_CDK5_CDK5_ST	Q8NEB9	PIK3C3	Q00535	CDK5	T668	E661A	661	Missense	distal	-7	no	18.639	18.631	PhosphoSitePlus;EPSD	TCGA;COSMIC	8.808	Down-regulation
CMGC_CDK_CDK5_CDK5_ST	Q8NEB9	PIK3C3	Q00535	CDK5	T668	T675I	675	Missense	distal	7	no	18.639	18.635	PhosphoSitePlus;EPSD	TCGA	8.808	Down-regulation
CMGC_CDK_CDK5_CDK5_ST	P56817	BACE1	Q00535	CDK5	S83	S83N	83	Missense	central	0	yes	17.349	0.000	EPSD	TCGA;ICGC;COSMIC	8.808	Loss
CMGC_CDK_CDK5_CDK5_ST	P56817	BACE1	Q00535	CDK5	S83	T87A	87	Missense	distal	4	no	17.349	17.289	EPSD	TCGA;ICGC;COSMIC	8.808	Down-regulation
CMGC_CDK_CDK5_CDK5_ST	P56817	BACE1	Q00535	CDK5	S83	V77M	77	Missense	distal	-6	no	17.349	17.245	EPSD	TCGA;ICGC;COSMIC	8.808	Down-regulation
CMGC_CDK_CDK5_CDK5_ST	P56817	BACE1	Q00535	CDK5	S83	M79V	79	Missense	distal	-4	no	17.349	17.936	EPSD	TCGA;ICGC;COSMIC	8.808	Up-regulation
CMGC_CDK_CDK5_CDK5_ST	P56817	BACE1	Q00535	CDK5	S83	T87M	87	Missense	distal	4	no	17.349	17.256	EPSD	TCGA;ICGC;COSMIC	8.808	Down-regulation
CMGC_CDK_CDK5_CDK5_ST	P56817	BACE1	Q00535	CDK5	T252	W250R	250	Missense	proximal	-2	no	19.204	19.577	PhosphoSitePlus	TCGA;COSMIC	8.808	Up-regulation
CMGC_CDK_CDK5_CDK5_ST	P56817	BACE1	Q00535	CDK5	T252	L249I	249	Missense	distal	-3	no	19.204	19.236	PhosphoSitePlus	TCGA	8.808	Up-regulation
CMGC_CDK_CDK5_CDK5_ST	P56817	BACE1	Q00535	CDK5	T252	R255Q	255	Missense	distal	3	no	19.204	17.401	PhosphoSitePlus	TCGA;COSMIC	8.808	Down-regulation
CMGC_CDK_CDK5_CDK5_ST	P05067	APP	Q00535	CDK5	T381	E380K	380	Missense	proximal	-1	no	16.419	16.425	EPSD	TCGA;COSMIC;CCLE	8.808	Up-regulation
CMGC_CDK_CDK5_CDK5_ST	P05067	APP	Q00535	CDK5	T598	E599Q	599	Missense	proximal	1	no	-3.974	9.261	EPSD	TCGA;COSMIC	8.808	Gain
CMGC_CDK_CDK5_CDK5_ST	P05067	APP	Q00535	CDK5	T743	R747P	747	Missense	distal	4	no	16.502	16.484	EPSD	TCGA;COSMIC	8.808	Down-regulation
CMGC_CDK_CDK5_CDK5_ST	P05067	APP	Q00535	CDK5	T743	R747C	747	Missense	distal	4	no	16.502	16.394	EPSD	TCGA;COSMIC;GDSC	8.808	Down-regulation
CMGC_CDK_CDK5_CDK5_ST	P05067	APP	Q00535	CDK5	T743	R747H	747	Missense	distal	4	no	16.502	16.463	EPSD	TCGA;COSMIC	8.808	Down-regulation
CMGC_CDK_CDK5_CDK5_ST	P49418	AMPH	Q00535	CDK5	T260	E265K	265	Missense	distal	5	no	17.115	17.366	EPSD	TCGA;ICGC;COSMIC	8.808	Up-regulation
CMGC_CDK_CDK5_CDK5_ST	P49418	AMPH	Q00535	CDK5	T260	P263L	263	Missense	distal	3	no	17.115	16.044	EPSD	TCGA;ICGC;COSMIC	8.808	Down-regulation
CMGC_CDK_CDK5_CDK5_ST	P49418	AMPH	Q00535	CDK5	T260	P264L	264	Missense	distal	4	no	17.115	17.034	EPSD	TCGA	8.808	Down-regulation
CMGC_CDK_CDK5_CDK5_ST	P49418	AMPH	Q00535	CDK5	T260	A258V	258	Missense	proximal	-2	no	17.115	17.312	EPSD	TCGA;ICGC;COSMIC	8.808	Up-regulation
CMGC_CDK_CDK5_CDK5_ST	P49418	AMPH	Q00535	CDK5	T260	R256H	256	Missense	distal	-4	no	17.115	16.896	EPSD	TCGA;ICGC;COSMIC	8.808	Down-regulation
CMGC_CDK_CDK5_CDK5_ST	P49418	AMPH	Q00535	CDK5	T260	L255P	255	Missense	distal	-5	no	17.115	17.313	EPSD	TCGA;ICGC;COSMIC	8.808	Up-regulation
CMGC_CDK_CDK5_CDK5_ST	P49418	AMPH	Q00535	CDK5	S262	E265K	265	Missense	distal	3	no	17.302	19.588	EPSD	TCGA;ICGC;COSMIC	8.808	Up-regulation
CMGC_CDK_CDK5_CDK5_ST	P49418	AMPH	Q00535	CDK5	S262	P263L	263	Missense	proximal	1	no	17.302	5.352	EPSD	TCGA;ICGC;COSMIC	8.808	Loss
CMGC_CDK_CDK5_CDK5_ST	P49418	AMPH	Q00535	CDK5	S262	P264L	264	Missense	proximal	2	no	17.302	17.137	EPSD	TCGA	8.808	Down-regulation
CMGC_CDK_CDK5_CDK5_ST	P49418	AMPH	Q00535	CDK5	S262	A258V	258	Missense	distal	-4	no	17.302	17.722	EPSD	TCGA;ICGC;COSMIC	8.808	Up-regulation
CMGC_CDK_CDK5_CDK5_ST	P49418	AMPH	Q00535	CDK5	S262	R256H	256	Missense	distal	-6	no	17.302	17.236	EPSD	TCGA;ICGC;COSMIC	8.808	Down-regulation
CMGC_CDK_CDK5_CDK5_ST	P49418	AMPH	Q00535	CDK5	S262	L255P	255	Missense	distal	-7	no	17.302	17.354	EPSD	TCGA;ICGC;COSMIC	8.808	Up-regulation
CMGC_CDK_CDK5_CDK5_ST	P49418	AMPH	Q00535	CDK5	S268	E265K	265	Missense	distal	-3	no	17.965	18.037	EPSD	TCGA;ICGC;COSMIC	8.808	Up-regulation
CMGC_CDK_CDK5_CDK5_ST	P49418	AMPH	Q00535	CDK5	S268	P263L	263	Missense	distal	-5	no	17.965	17.768	EPSD	TCGA;ICGC;COSMIC	8.808	Down-regulation
CMGC_CDK_CDK5_CDK5_ST	P49418	AMPH	Q00535	CDK5	S268	P264L	264	Missense	distal	-4	no	17.965	17.492	EPSD	TCGA	8.808	Down-regulation
CMGC_CDK_CDK5_CDK5_ST	P49418	AMPH	Q00535	CDK5	S272	E265K	265	Missense	distal	-7	no	18.353	18.416	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	8.808	Up-regulation
CMGC_CDK_CDK5_CDK5_ST	P49418	AMPH	Q00535	CDK5	S272	P277L	277	Missense	distal	5	no	18.353	18.180	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	8.808	Down-regulation
CMGC_CDK_CDK5_CDK5_ST	P49418	AMPH	Q00535	CDK5	S276	P277L	277	Missense	proximal	1	no	18.246	6.296	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	8.808	Loss
CMGC_CDK_CDK5_CDK5_ST	P49418	AMPH	Q00535	CDK5	S276	A282V	282	Missense	distal	6	no	18.246	18.255	EPSD;PhosphoSitePlus	TCGA;ICGC	8.808	Up-regulation
CMGC_CDK_CDK5_CDK5_ST	P49418	AMPH	Q00535	CDK5	S285	R292W	292	Missense	distal	7	no	17.350	17.339	PhosphoSitePlus;EPSD	TCGA;ICGC;COSMIC	8.808	Down-regulation
CMGC_CDK_CDK5_CDK5_ST	P49418	AMPH	Q00535	CDK5	S285	R290W	290	Missense	distal	5	no	17.350	17.173	PhosphoSitePlus;EPSD	TCGA;ICGC;COSMIC	8.808	Down-regulation
CMGC_CDK_CDK5_CDK5_ST	P49418	AMPH	Q00535	CDK5	S285	R290Q	290	Missense	distal	5	no	17.350	17.226	PhosphoSitePlus;EPSD	TCGA;ICGC;COSMIC	8.808	Down-regulation
CMGC_CDK_CDK5_CDK5_ST	P49418	AMPH	Q00535	CDK5	S285	A287T	287	Missense	proximal	2	no	17.350	17.469	PhosphoSitePlus;EPSD	TCGA;ICGC;COSMIC	8.808	Up-regulation
CMGC_CDK_CDK5_CDK5_ST	P49418	AMPH	Q00535	CDK5	S285	S285Y	285	Missense	central	0	yes	17.350	0.000	PhosphoSitePlus;EPSD	TCGA;ICGC;COSMIC	8.808	Loss
CMGC_CDK_CDK5_CDK5_ST	P49418	AMPH	Q00535	CDK5	S285	A282V	282	Missense	distal	-3	no	17.350	17.389	PhosphoSitePlus;EPSD	TCGA;ICGC	8.808	Up-regulation
CMGC_CDK_CDK5_CDK5_ST	P49418	AMPH	Q00535	CDK5	S293	R292W	292	Missense	proximal	-1	no	16.929	16.925	EPSD	TCGA;ICGC;COSMIC	8.808	Down-regulation
CMGC_CDK_CDK5_CDK5_ST	P49418	AMPH	Q00535	CDK5	S293	R290W	290	Missense	distal	-3	no	16.929	16.876	EPSD	TCGA;ICGC;COSMIC	8.808	Down-regulation
CMGC_CDK_CDK5_CDK5_ST	P49418	AMPH	Q00535	CDK5	S293	R290Q	290	Missense	distal	-3	no	16.929	16.903	EPSD	TCGA;ICGC;COSMIC	8.808	Down-regulation
CMGC_CDK_CDK5_CDK5_ST	P49418	AMPH	Q00535	CDK5	S293	A287T	287	Missense	distal	-6	no	16.929	17.015	EPSD	TCGA;ICGC;COSMIC	8.808	Up-regulation
CMGC_CDK_CDK5_CDK5_ST	P49418	AMPH	Q00535	CDK5	S293	G300R	300	Missense	distal	7	no	16.929	16.941	EPSD	TCGA;ICGC;COSMIC	8.808	Up-regulation
CMGC_CDK_CDK5_CDK5_ST	P49418	AMPH	Q00535	CDK5	S295	P302S	302	Missense	distal	7	no	10.870	10.871	EPSD	TCGA	8.808	Up-regulation
CMGC_CDK_CDK5_CDK5_ST	P49418	AMPH	Q00535	CDK5	S295	R292W	292	Missense	distal	-3	no	10.870	10.817	EPSD	TCGA;ICGC;COSMIC	8.808	Down-regulation
CMGC_CDK_CDK5_CDK5_ST	P49418	AMPH	Q00535	CDK5	S295	R290W	290	Missense	distal	-5	no	10.870	10.611	EPSD	TCGA;ICGC;COSMIC	8.808	Down-regulation
CMGC_CDK_CDK5_CDK5_ST	P49418	AMPH	Q00535	CDK5	S295	R290Q	290	Missense	distal	-5	no	10.870	10.710	EPSD	TCGA;ICGC;COSMIC	8.808	Down-regulation
CMGC_CDK_CDK5_CDK5_ST	P49418	AMPH	Q00535	CDK5	S295	G300R	300	Missense	distal	5	no	10.870	11.037	EPSD	TCGA;ICGC;COSMIC	8.808	Up-regulation
CMGC_CDK_CDK5_CDK5_ST	P49418	AMPH	Q00535	CDK5	T297	G300R	300	Missense	distal	3	no	8.752	10.134	EPSD	TCGA;ICGC;COSMIC	8.808	Gain
CMGC_CDK_CDK5_CDK5_ST	P49418	AMPH	Q00535	CDK5	T310	Q317K	317	Missense	distal	7	no	18.925	18.936	EPSD	TCGA;ICGC;COSMIC	8.808	Up-regulation
CMGC_CDK_CDK5_CDK5_ST	P49418	AMPH	Q00535	CDK5	T310	K308N	308	Missense	proximal	-2	no	18.925	18.742	EPSD	TCGA;ICGC;COSMIC	8.808	Down-regulation
CMGC_CDK_CDK5_CDK5_ST	P49418	AMPH	Q00535	CDK5	T310	P304S	304	Missense	distal	-6	no	18.925	18.964	EPSD	TCGA;ICGC;COSMIC	8.808	Up-regulation
CMGC_CDK_CDK5_CDK5_ST	P49418	AMPH	Q00535	CDK5	T310	E314K	314	Missense	distal	4	no	18.925	19.042	EPSD	TCGA;ICGC;COSMIC	8.808	Up-regulation
CMGC_CDK_CDK5_CDK5_ST	P49418	AMPH	Q00535	CDK5	T336	E331Q	331	Missense	distal	-5	no	15.867	15.961	EPSD	TCGA;ICGC;COSMIC	8.808	Up-regulation
CMGC_CDK_CDK5_CDK5_ST	P49418	AMPH	Q00535	CDK5	T336	P330L	330	Missense	distal	-6	no	15.867	15.784	EPSD	TCGA;ICGC;COSMIC	8.808	Down-regulation
CMGC_CDK_CDK5_CDK5_ST	P49418	AMPH	Q00535	CDK5	T336	V329F	329	Missense	distal	-7	no	15.867	15.801	EPSD	TCGA;ICGC;COSMIC	8.808	Down-regulation
CMGC_CDK_CDK5_CDK5_ST	P49418	AMPH	Q00535	CDK5	T336	Q339L	339	Missense	distal	3	no	15.867	15.200	EPSD	TCGA;ICGC;COSMIC	8.808	Down-regulation
CMGC_CDK_CDK5_CDK5_ST	P49418	AMPH	Q00535	CDK5	T336	P337H	337	Missense	proximal	1	no	15.867	-2.645	EPSD	TCGA;ICGC;COSMIC	8.808	Loss
CMGC_CDK_CDK5_CDK5_ST	P49418	AMPH	Q00535	CDK5	T445	A447T	447	Missense	proximal	2	no	16.941	17.059	EPSD	TCGA;ICGC;COSMIC	8.808	Up-regulation
CMGC_CDK_CDK5_CDK5_ST	P49418	AMPH	Q00535	CDK5	T445	A443S	443	Missense	proximal	-2	no	16.941	17.219	EPSD	TCGA;ICGC;COSMIC	8.808	Up-regulation
CMGC_CDK_CDK5_CDK5_ST	Q15078	CDK5R1	Q00535	CDK5	S8	R12Q	12	Missense	distal	4	no	18.241	18.194	PhosphoSitePlus;EPSD	TCGA;ICGC;COSMIC	8.808	Down-regulation
CMGC_CDK_CDK5_CDK5_ST	Q15078	CDK5R1	Q00535	CDK5	S135	P131S	131	Missense	distal	-4	no	8.537	8.883	EPSD	TCGA;ICGC;COSMIC	8.808	Gain
CMGC_CDK_CDK5_CDK5_ST	Q15078	CDK5R1	Q00535	CDK5	S135	A136T	136	Missense	proximal	1	no	8.537	9.076	EPSD	TCGA;ICGC;COSMIC	8.808	Gain
CMGC_CDK_CDK5_CDK5_ST	Q15078	CDK5R1	Q00535	CDK5	T138	P131S	131	Missense	distal	-7	no	19.097	19.101	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	8.808	Up-regulation
CMGC_CDK_CDK5_CDK5_ST	Q15078	CDK5R1	Q00535	CDK5	T138	R141Q	141	Missense	distal	3	no	19.097	17.294	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	8.808	Down-regulation
CMGC_CDK_CDK5_CDK5_ST	Q15078	CDK5R1	Q00535	CDK5	T138	A136T	136	Missense	proximal	-2	no	19.097	19.334	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	8.808	Up-regulation
CMGC_CDK_CDK5_CDK5_ST	Q96QB1	DLC1	Q00535	CDK5	S306	P307T	307	Missense	proximal	1	no	19.469	8.981	EPSD	TCGA;ICGC;COSMIC	8.808	Down-regulation
CMGC_CDK_CDK5_CDK5_ST	Q96QB1	DLC1	Q00535	CDK5	S306	E313K	313	Missense	distal	7	no	19.469	19.484	EPSD	TCGA;ICGC;COSMIC;GDSC;CCLE	8.808	Up-regulation
CMGC_CDK_CDK5_CDK5_ST	Q96QB1	DLC1	Q00535	CDK5	S306	N304S	304	Missense	proximal	-2	no	19.469	19.582	EPSD	TCGA;ICGC;COSMIC	8.808	Up-regulation
CMGC_CDK_CDK5_CDK5_ST	Q96QB1	DLC1	Q00535	CDK5	S306	N304T	304	Missense	proximal	-2	no	19.469	19.541	EPSD	TCGA;ICGC;COSMIC	8.808	Up-regulation
CMGC_CDK_CDK5_CDK5_ST	Q96QB1	DLC1	Q00535	CDK5	S378	T382R	382	Missense	distal	4	no	18.836	18.855	EPSD	TCGA;ICGC;COSMIC	8.808	Up-regulation
CMGC_CDK_CDK5_CDK5_ST	Q96QB1	DLC1	Q00535	CDK5	S378	L373I	373	Missense	distal	-5	no	18.836	18.924	EPSD	TCGA;ICGC;COSMIC	8.808	Up-regulation
CMGC_CDK_CDK5_CDK5_ST	Q96QB1	DLC1	Q00535	CDK5	S378	A372T	372	Missense	distal	-6	no	18.836	18.922	EPSD	TCGA;ICGC;COSMIC	8.808	Up-regulation
CMGC_CDK_CDK5_CDK5_ST	Q96QB1	DLC1	Q00535	CDK5	T382	T382R	382	Missense	central	0	yes	18.246	0.000	EPSD	TCGA;ICGC;COSMIC	8.808	Loss
CMGC_CDK_CDK5_CDK5_ST	Q96QB1	DLC1	Q00535	CDK5	T382	H389L	389	Missense	distal	7	no	18.246	18.238	EPSD	TCGA;ICGC;COSMIC	8.808	Down-regulation
CMGC_CDK_CDK5_CDK5_ST	Q96QB1	DLC1	Q00535	CDK5	T382	R388Q	388	Missense	distal	6	no	18.246	18.235	EPSD	TCGA;ICGC;COSMIC	8.808	Down-regulation
CMGC_CDK_CDK5_CDK5_ST	Q96QB1	DLC1	Q00535	CDK5	T382	H389R	389	Missense	distal	7	no	18.246	18.252	EPSD	TCGA;ICGC	8.808	Up-regulation
CMGC_CDK_CDK5_CDK5_ST	Q96QB1	DLC1	Q00535	CDK5	T382	R387W	387	Missense	distal	5	no	18.246	18.069	EPSD	TCGA;ICGC;COSMIC	8.808	Down-regulation
CMGC_CDK_CDK5_CDK5_ST	Q96QB1	DLC1	Q00535	CDK5	T384	T382R	382	Missense	proximal	-2	no	10.132	10.216	EPSD	TCGA;ICGC;COSMIC	8.808	Up-regulation
CMGC_CDK_CDK5_CDK5_ST	Q96QB1	DLC1	Q00535	CDK5	T384	H389L	389	Missense	distal	5	no	10.132	9.987	EPSD	TCGA;ICGC;COSMIC	8.808	Down-regulation
CMGC_CDK_CDK5_CDK5_ST	Q96QB1	DLC1	Q00535	CDK5	T384	R388Q	388	Missense	distal	4	no	10.132	10.085	EPSD	TCGA;ICGC;COSMIC	8.808	Down-regulation
CMGC_CDK_CDK5_CDK5_ST	Q96QB1	DLC1	Q00535	CDK5	T384	H389R	389	Missense	distal	5	no	10.132	10.235	EPSD	TCGA;ICGC	8.808	Up-regulation
CMGC_CDK_CDK5_CDK5_ST	Q96QB1	DLC1	Q00535	CDK5	T384	R387W	387	Missense	distal	3	no	10.132	8.441	EPSD	TCGA;ICGC;COSMIC	8.808	Loss
CMGC_CDK_CDK5_CDK5_ST	Q96QB1	DLC1	Q00535	CDK5	S517	I516M	516	Missense	proximal	-1	no	19.931	19.927	EPSD	TCGA;COSMIC	8.808	Down-regulation
CMGC_CDK_CDK5_CDK5_ST	Q96QB1	DLC1	Q00535	CDK5	S517	H519D	519	Missense	proximal	2	no	19.931	19.840	EPSD	TCGA;COSMIC	8.808	Down-regulation
CMGC_CDK_CDK5_CDK5_ST	Q96QB1	DLC1	Q00535	CDK5	S517	A510V	510	Missense	distal	-7	no	19.931	19.966	EPSD	TCGA	8.808	Up-regulation
CMGC_CDK_CDK5_CDK5_ST	Q96QB1	DLC1	Q00535	CDK5	S517	V511A	511	Missense	distal	-6	no	19.931	19.861	EPSD	TCGA;COSMIC	8.808	Down-regulation
CMGC_CDK_CDK5_CDK5_ST	Q96QB1	DLC1	Q00535	CDK5	S557	D561N	561	Missense	distal	4	no	17.606	17.636	PhosphoSitePlus;EPSD	TCGA;COSMIC	8.808	Up-regulation
CMGC_CDK_CDK5_CDK5_ST	Q96QB1	DLC1	Q00535	CDK5	S557	E552Q	552	Missense	distal	-5	no	17.606	17.700	PhosphoSitePlus;EPSD	TCGA;COSMIC	8.808	Up-regulation
CMGC_CDK_CDK5_CDK5_ST	Q96QB1	DLC1	Q00535	CDK5	S566	P564S	564	Missense	proximal	-2	no	16.698	16.599	EPSD	TCGA;COSMIC	8.808	Down-regulation
CMGC_CDK_CDK5_CDK5_ST	Q96QB1	DLC1	Q00535	CDK5	S566	D561N	561	Missense	distal	-5	no	16.698	16.772	EPSD	TCGA;COSMIC	8.808	Up-regulation
CMGC_CDK_CDK5_CDK5_ST	Q96QB1	DLC1	Q00535	CDK5	T615	A614T	614	Missense	proximal	-1	no	17.849	17.853	EPSD	TCGA;COSMIC	8.808	Up-regulation
CMGC_CDK_CDK5_CDK5_ST	Q96QB1	DLC1	Q00535	CDK5	T615	P616H	616	Missense	proximal	1	no	17.849	-0.664	EPSD	TCGA;ICGC;COSMIC	8.808	Loss
CMGC_CDK_CDK5_CDK5_ST	Q96QB1	DLC1	Q00535	CDK5	T615	S620F	620	Missense	distal	5	no	17.849	17.609	EPSD	TCGA;COSMIC;GDSC;CCLE	8.808	Down-regulation
CMGC_CDK_CDK5_CDK5_ST	Q96QB1	DLC1	Q00535	CDK5	T615	R617Q	617	Missense	proximal	2	no	17.849	17.709	EPSD	TCGA;COSMIC	8.808	Down-regulation
CMGC_CDK_CDK5_CDK5_ST	Q96QB1	DLC1	Q00535	CDK5	S642	P643S	643	Missense	proximal	1	no	16.005	4.103	EPSD;PhosphoSitePlus	TCGA	8.808	Loss
CMGC_CDK_CDK5_CDK5_ST	Q96QB1	DLC1	Q00535	CDK5	S642	G638D	638	Missense	distal	-4	no	16.005	16.169	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	8.808	Up-regulation
CMGC_CDK_CDK5_CDK5_ST	Q96QB1	DLC1	Q00535	CDK5	S735	T738S	738	Missense	distal	3	no	9.687	9.131	EPSD	TCGA;COSMIC	8.808	Down-regulation
CMGC_CDK_CDK5_CDK5_ST	Q96QB1	DLC1	Q00535	CDK5	S735	V734I	734	Missense	proximal	-1	no	9.687	9.686	EPSD	TCGA;COSMIC	8.808	Down-regulation
CMGC_CDK_CDK5_CDK5_ST	Q96QB1	DLC1	Q00535	CDK5	S745	T738S	738	Missense	distal	-7	no	9.599	9.613	EPSD	TCGA;COSMIC	8.808	Up-regulation
CMGC_CDK_CDK5_CDK5_ST	Q96QB1	DLC1	Q00535	CDK5	S745	S747L	747	Missense	proximal	2	no	9.599	9.451	EPSD	TCGA;COSMIC	8.808	Down-regulation
CMGC_CDK_CDK5_CDK5_ST	Q96QB1	DLC1	Q00535	CDK5	T755	T760M	760	Missense	distal	5	no	17.881	17.678	EPSD	TCGA;COSMIC	8.808	Down-regulation
CMGC_CDK_CDK5_CDK5_ST	Q96QB1	DLC1	Q00535	CDK5	T755	P758L	758	Missense	distal	3	no	17.881	16.809	EPSD	TCGA;COSMIC	8.808	Down-regulation
CMGC_CDK_CDK5_CDK5_ST	Q96QB1	DLC1	Q00535	CDK5	T755	T755M	755	Missense	central	0	yes	17.881	0.000	EPSD	TCGA;ICGC;COSMIC	8.808	Loss
CMGC_CDK_CDK5_CDK5_ST	Q96QB1	DLC1	Q00535	CDK5	S757	T760M	760	Missense	distal	3	no	18.767	17.270	EPSD	TCGA;COSMIC	8.808	Down-regulation
CMGC_CDK_CDK5_CDK5_ST	Q96QB1	DLC1	Q00535	CDK5	S757	P758L	758	Missense	proximal	1	no	18.767	6.817	EPSD	TCGA;COSMIC	8.808	Loss
CMGC_CDK_CDK5_CDK5_ST	Q96QB1	DLC1	Q00535	CDK5	S757	S764R	764	Missense	distal	7	no	18.767	18.769	EPSD	TCGA;COSMIC	8.808	Up-regulation
CMGC_CDK_CDK5_CDK5_ST	Q96QB1	DLC1	Q00535	CDK5	S757	T755M	755	Missense	proximal	-2	no	18.767	18.334	EPSD	TCGA;ICGC;COSMIC	8.808	Down-regulation
CMGC_CDK_CDK5_CDK5_ST	Q96QB1	DLC1	Q00535	CDK5	S828	S830L	830	Missense	proximal	2	no	17.712	17.564	EPSD	TCGA;ICGC;COSMIC	8.808	Down-regulation
CMGC_CDK_CDK5_CDK5_ST	Q96QB1	DLC1	Q00535	CDK5	S828	L822F	822	Missense	distal	-6	no	17.712	17.661	EPSD	TCGA;COSMIC	8.808	Down-regulation
CMGC_CDK_CDK5_CDK5_ST	Q96QB1	DLC1	Q00535	CDK5	S828	G834S	834	Missense	distal	6	no	17.712	17.722	EPSD	TCGA;COSMIC	8.808	Up-regulation
CMGC_CDK_CDK5_CDK5_ST	Q96QB1	DLC1	Q00535	CDK5	S859	N855K	855	Missense	distal	-4	no	17.929	18.316	EPSD;PhosphoSitePlus	TCGA;COSMIC	8.808	Up-regulation
CMGC_CDK_CDK5_CDK5_ST	Q96QB1	DLC1	Q00535	CDK5	S859	R866C	866	Missense	distal	7	no	17.929	17.912	EPSD;PhosphoSitePlus	TCGA;COSMIC	8.808	Down-regulation
CMGC_CDK_CDK5_CDK5_ST	Q96QB1	DLC1	Q00535	CDK5	S859	R866P	866	Missense	distal	7	no	17.929	17.926	EPSD;PhosphoSitePlus	TCGA;COSMIC	8.808	Down-regulation
CMGC_CDK_CDK5_CDK5_ST	Q96QB1	DLC1	Q00535	CDK5	S859	D858N	858	Missense	proximal	-1	no	17.929	17.931	EPSD;PhosphoSitePlus	TCGA;COSMIC	8.808	Up-regulation
CMGC_CDK_CDK5_CDK5_ST	Q96QB1	DLC1	Q00535	CDK5	S859	K861N	861	Missense	proximal	2	no	17.929	17.734	EPSD;PhosphoSitePlus	TCGA;COSMIC	8.808	Down-regulation
CMGC_CDK_CDK5_CDK5_ST	Q96QB1	DLC1	Q00535	CDK5	S874	D880E	880	Missense	distal	6	no	9.351	9.353	EPSD	TCGA;COSMIC	8.808	Up-regulation
CMGC_CDK_CDK5_CDK5_ST	Q96QB1	DLC1	Q00535	CDK5	S928	G931R	931	Missense	distal	3	no	7.871	9.253	EPSD	TCGA	8.808	Gain
CMGC_CDK_CDK5_CDK5_ST	Q96QB1	DLC1	Q00535	CDK5	S941	V940I	940	Missense	proximal	-1	no	17.171	17.169	EPSD	TCGA;COSMIC	8.808	Down-regulation
CMGC_CDK_CDK5_CDK5_ST	Q96QB1	DLC1	Q00535	CDK5	S941	P947L	947	Missense	distal	6	no	17.171	17.157	EPSD	TCGA;COSMIC	8.808	Down-regulation
CMGC_CDK_CDK5_CDK5_ST	Q96QB1	DLC1	Q00535	CDK5	S946	V940I	940	Missense	distal	-6	no	18.082	18.054	EPSD;PhosphoSitePlus	TCGA;COSMIC	8.808	Down-regulation
CMGC_CDK_CDK5_CDK5_ST	Q96QB1	DLC1	Q00535	CDK5	S946	P947L	947	Missense	proximal	1	no	18.082	6.132	EPSD;PhosphoSitePlus	TCGA;COSMIC	8.808	Loss
CMGC_CDK_CDK5_CDK5_ST	Q96QB1	DLC1	Q00535	CDK5	S946	P947S	947	Missense	proximal	1	no	18.082	6.180	EPSD;PhosphoSitePlus	TCGA;COSMIC	8.808	Loss
CMGC_CDK_CDK5_CDK5_ST	Q96QB1	DLC1	Q00535	CDK5	S995	R994M	994	Missense	proximal	-1	no	9.504	9.497	EPSD	TCGA;ICGC;COSMIC	8.808	Down-regulation
CMGC_CDK_CDK5_CDK5_ST	Q96QB1	DLC1	Q00535	CDK5	S995	H998R	998	Missense	distal	3	no	9.504	10.523	EPSD	TCGA;ICGC;COSMIC	8.808	Up-regulation
CMGC_CDK_CDK5_CDK5_ST	Q96QB1	DLC1	Q00535	CDK5	S995	A990S	990	Missense	distal	-5	no	9.504	9.685	EPSD	TCGA;COSMIC	8.808	Up-regulation
CMGC_CDK_CDK5_CDK5_ST	Q96QB1	DLC1	Q00535	CDK5	S1017	L1018P	1018	Missense	proximal	1	no	5.613	17.563	EPSD	TCGA;ICGC;COSMIC	8.808	Gain
CMGC_CDK_CDK5_CDK5_ST	Q96QB1	DLC1	Q00535	CDK5	S1291	S1296Y	1296	Missense	distal	5	no	10.935	10.758	EPSD	TCGA;COSMIC	8.808	Down-regulation
CMGC_CDK_CDK5_CDK5_ST	Q96QB1	DLC1	Q00535	CDK5	S1291	R1294C	1294	Missense	distal	3	no	10.935	8.639	EPSD	TCGA;COSMIC	8.808	Loss
CMGC_CDK_CDK5_CDK5_ST	Q96QB1	DLC1	Q00535	CDK5	S1291	E1288K	1288	Missense	distal	-3	no	10.935	11.008	EPSD	TCGA;COSMIC;CCLE	8.808	Up-regulation
CMGC_CDK_CDK5_CDK5_ST	Q96QB1	DLC1	Q00535	CDK5	S1291	N1295H	1295	Missense	distal	4	no	10.935	10.943	EPSD	TCGA;COSMIC	8.808	Up-regulation
CMGC_CDK_CDK5_CDK5_ST	Q96QB1	DLC1	Q00535	CDK5	S1291	R1294H	1294	Missense	distal	3	no	10.935	9.916	EPSD	TCGA;COSMIC	8.808	Down-regulation
CMGC_CDK_CDK5_CDK5_ST	Q96QB1	DLC1	Q00535	CDK5	S1516	S1514F	1514	Missense	proximal	-2	no	9.023	8.464	EPSD	TCGA;COSMIC	8.808	Loss
CMGC_CDK_CDK5_CDK5_ST	Q96QB1	DLC1	Q00535	CDK5	S1516	K1523E	1523	Missense	distal	7	no	9.023	9.007	EPSD	TCGA;COSMIC	8.808	Down-regulation
CMGC_CDK_CDK5_CDK5_ST	Q96QB1	DLC1	Q00535	CDK5	S1516	K1510T	1510	Missense	distal	-6	no	9.023	8.953	EPSD	TCGA;COSMIC	8.808	Down-regulation
CMGC_CDK_CDK5_CDK5_ST	Q3V6T2	CCDC88A	Q00535	CDK5	S16	Q12H	12	Missense	distal	-4	no	18.744	18.534	EPSD	TCGA;ICGC;COSMIC	8.808	Down-regulation
CMGC_CDK_CDK5_CDK5_ST	Q3V6T2	CCDC88A	Q00535	CDK5	S233	H226Y	226	Missense	distal	-7	no	17.964	17.929	EPSD	TCGA;ICGC;COSMIC	8.808	Down-regulation
CMGC_CDK_CDK5_CDK5_ST	Q3V6T2	CCDC88A	Q00535	CDK5	S245	L249V	249	Missense	distal	4	no	9.460	9.523	EPSD	TCGA;ICGC;COSMIC	8.808	Up-regulation
CMGC_CDK_CDK5_CDK5_ST	Q3V6T2	CCDC88A	Q00535	CDK5	S1666	H1668Y	1668	Missense	proximal	2	no	9.088	8.953	EPSD	TCGA;ICGC;COSMIC	8.808	Down-regulation
CMGC_CDK_CDK5_CDK5_ST	Q3V6T2	CCDC88A	Q00535	CDK5	S1666	H1668R	1668	Missense	proximal	2	no	9.088	9.203	EPSD	TCGA;ICGC;COSMIC	8.808	Up-regulation
CMGC_CDK_CDK5_CDK5_ST	Q3V6T2	CCDC88A	Q00535	CDK5	S1675	H1668Y	1668	Missense	distal	-7	no	17.543	17.508	PhosphoSitePlus	TCGA;ICGC;COSMIC	8.808	Down-regulation
CMGC_CDK_CDK5_CDK5_ST	Q3V6T2	CCDC88A	Q00535	CDK5	S1675	H1668R	1668	Missense	distal	-7	no	17.543	17.574	PhosphoSitePlus	TCGA;ICGC;COSMIC	8.808	Up-regulation
CMGC_CDK_CDK5_CDK5_ST	Q3V6T2	CCDC88A	Q00535	CDK5	T1774	S1768Y	1768	Missense	distal	-6	no	16.890	16.756	EPSD	TCGA;COSMIC	8.808	Down-regulation
CMGC_CDK_CDK5_CDK5_ST	P14416	DRD2	Q00535	CDK5	S19	D12E	12	Missense	distal	-7	no	9.063	9.061	EPSD	TCGA;ICGC;COSMIC	8.808	Down-regulation
CMGC_CDK_CDK5_CDK5_ST	P14416	DRD2	Q00535	CDK5	S19	W18R	18	Missense	proximal	-1	no	9.063	9.067	EPSD	TCGA;ICGC;COSMIC	8.808	Up-regulation
CMGC_CDK_CDK5_CDK5_ST	P14416	DRD2	Q00535	CDK5	S296	P297H	297	Missense	proximal	1	no	17.780	-0.732	EPSD	TCGA;ICGC;COSMIC	8.808	Loss
CMGC_CDK_CDK5_CDK5_ST	P14416	DRD2	Q00535	CDK5	S296	S296I	296	Missense	central	0	yes	17.780	0.000	EPSD	TCGA;ICGC;COSMIC	8.808	Loss
CMGC_CDK_CDK5_CDK5_ST	P14416	DRD2	Q00535	CDK5	S296	P299S	299	Missense	distal	3	no	17.780	17.760	EPSD	TCGA;ICGC;COSMIC	8.808	Down-regulation
CMGC_CDK_CDK5_CDK5_ST	P14416	DRD2	Q00535	CDK5	S296	P289L	289	Missense	distal	-7	no	17.780	17.728	EPSD	TCGA;ICGC;COSMIC	8.808	Down-regulation
CMGC_CDK_CDK5_CDK5_ST	P14416	DRD2	Q00535	CDK5	S296	E291K	291	Missense	distal	-5	no	17.780	18.070	EPSD	TCGA;ICGC;COSMIC;CCLE	8.808	Up-regulation
CMGC_CDK_CDK5_CDK5_ST	P14416	DRD2	Q00535	CDK5	S321	S321R	321	Missense	central	0	yes	20.081	0.000	PhosphoSitePlus	TCGA;ICGC;COSMIC	8.808	Loss
CMGC_CDK_CDK5_CDK5_ST	P14416	DRD2	Q00535	CDK5	S321	H316P	316	Missense	distal	-5	no	20.081	20.151	PhosphoSitePlus	TCGA;ICGC;COSMIC;CCLE	8.808	Up-regulation
CMGC_CDK_CDK5_CDK5_ST	P14416	DRD2	Q00535	CDK5	S321	H316Q	316	Missense	distal	-5	no	20.081	20.092	PhosphoSitePlus	TCGA;ICGC;COSMIC	8.808	Up-regulation
CMGC_CDK_CDK5_CDK5_ST	P14416	DRD2	Q00535	CDK5	S321	A323V	323	Missense	proximal	2	no	20.081	20.162	PhosphoSitePlus	TCGA;ICGC;COSMIC	8.808	Up-regulation
CMGC_CDK_CDK5_CDK5_ST	P14416	DRD2	Q00535	CDK5	S359	K356R	356	Missense	distal	-3	no	10.442	10.422	EPSD	TCGA;ICGC;COSMIC	8.808	Down-regulation
CMGC_CDK_CDK5_CDK5_ST	P14416	DRD2	Q00535	CDK5	S359	R352W	352	Missense	distal	-7	no	10.442	10.392	EPSD	TCGA;ICGC;COSMIC	8.808	Down-regulation
CMGC_CDK_CDK5_CDK5_ST	P14416	DRD2	Q00535	CDK5	S359	L363H	363	Missense	distal	4	no	10.442	10.502	EPSD	TCGA;ICGC;COSMIC	8.808	Up-regulation
CMGC_CDK_CDK5_CDK5_ST	P14416	DRD2	Q00535	CDK5	S359	S364F	364	Missense	distal	5	no	10.442	10.203	EPSD	TCGA;ICGC;COSMIC	8.808	Down-regulation
CMGC_CDK_CDK5_CDK5_ST	Q13136	PPFIA1	Q00535	CDK5	S26	D33N	33	Missense	distal	7	no	18.306	18.310	EPSD	TCGA;ICGC;COSMIC	8.808	Up-regulation
CMGC_CDK_CDK5_CDK5_ST	Q13136	PPFIA1	Q00535	CDK5	S26	G25S	25	Missense	proximal	-1	no	18.306	18.311	EPSD	TCGA;ICGC;COSMIC	8.808	Up-regulation
CMGC_CDK_CDK5_CDK5_ST	Q13136	PPFIA1	Q00535	CDK5	S26	G21D	21	Missense	distal	-5	no	18.306	18.312	EPSD	TCGA;ICGC;COSMIC	8.808	Up-regulation
CMGC_CDK_CDK5_CDK5_ST	Q13136	PPFIA1	Q00535	CDK5	S28	D33N	33	Missense	distal	5	no	9.567	9.636	EPSD	TCGA;ICGC;COSMIC	8.808	Up-regulation
CMGC_CDK_CDK5_CDK5_ST	Q13136	PPFIA1	Q00535	CDK5	S28	G25S	25	Missense	distal	-3	no	9.567	9.607	EPSD	TCGA;ICGC;COSMIC	8.808	Up-regulation
CMGC_CDK_CDK5_CDK5_ST	Q13136	PPFIA1	Q00535	CDK5	S28	G21D	21	Missense	distal	-7	no	9.567	9.575	EPSD	TCGA;ICGC;COSMIC	8.808	Up-regulation
CMGC_CDK_CDK5_CDK5_ST	Q13136	PPFIA1	Q00535	CDK5	S150	P151Q	151	Missense	proximal	1	no	18.030	9.054	EPSD	TCGA;ICGC;COSMIC	8.808	Down-regulation
CMGC_CDK_CDK5_CDK5_ST	Q13136	PPFIA1	Q00535	CDK5	S150	E157K	157	Missense	distal	7	no	18.030	18.046	EPSD	TCGA;ICGC;COSMIC	8.808	Up-regulation
CMGC_CDK_CDK5_CDK5_ST	Q13136	PPFIA1	Q00535	CDK5	S150	A148V	148	Missense	proximal	-2	no	18.030	18.226	EPSD	TCGA;ICGC;COSMIC	8.808	Up-regulation
CMGC_CDK_CDK5_CDK5_ST	Q13136	PPFIA1	Q00535	CDK5	S150	G153D	153	Missense	distal	3	no	18.030	17.379	EPSD	TCGA;ICGC;COSMIC	8.808	Down-regulation
CMGC_CDK_CDK5_CDK5_ST	Q13136	PPFIA1	Q00535	CDK5	T230	T233M	233	Missense	distal	3	no	17.080	15.583	EPSD	TCGA;ICGC;COSMIC	8.808	Down-regulation
CMGC_CDK_CDK5_CDK5_ST	Q13136	PPFIA1	Q00535	CDK5	S485	E491K	491	Missense	distal	6	no	8.846	8.865	EPSD	TCGA;ICGC;COSMIC	8.808	Up-regulation
CMGC_CDK_CDK5_CDK5_ST	Q13136	PPFIA1	Q00535	CDK5	S485	L479F	479	Missense	distal	-6	no	8.846	8.795	EPSD	TCGA;ICGC;COSMIC	8.808	Loss
CMGC_CDK_CDK5_CDK5_ST	Q13136	PPFIA1	Q00535	CDK5	S618	S620G	620	Missense	proximal	2	no	18.198	18.124	EPSD	TCGA;ICGC;COSMIC	8.808	Down-regulation
CMGC_CDK_CDK5_CDK5_ST	Q13136	PPFIA1	Q00535	CDK5	S618	P619L	619	Missense	proximal	1	no	18.198	6.248	EPSD	TCGA;ICGC;COSMIC	8.808	Loss
CMGC_CDK_CDK5_CDK5_ST	Q13136	PPFIA1	Q00535	CDK5	S679	S680P	680	Missense	proximal	1	no	5.009	16.910	EPSD	TCGA;ICGC;COSMIC	8.808	Gain
CMGC_CDK_CDK5_CDK5_ST	Q13136	PPFIA1	Q00535	CDK5	S693	R699H	699	Missense	distal	6	no	18.047	18.036	EPSD	TCGA;ICGC;COSMIC	8.808	Down-regulation
CMGC_CDK_CDK5_CDK5_ST	Q13136	PPFIA1	Q00535	CDK5	S693	S700F	700	Missense	distal	7	no	18.047	18.030	EPSD	TCGA;ICGC;COSMIC	8.808	Down-regulation
CMGC_CDK_CDK5_CDK5_ST	Q13136	PPFIA1	Q00535	CDK5	S693	S688L	688	Missense	distal	-5	no	18.047	17.827	EPSD	TCGA;ICGC;COSMIC	8.808	Down-regulation
CMGC_CDK_CDK5_CDK5_ST	Q13136	PPFIA1	Q00535	CDK5	T701	R699H	699	Missense	proximal	-2	no	19.303	19.042	PhosphoSitePlus	TCGA;ICGC;COSMIC	8.808	Down-regulation
CMGC_CDK_CDK5_CDK5_ST	Q13136	PPFIA1	Q00535	CDK5	T701	S700F	700	Missense	proximal	-1	no	19.303	19.295	PhosphoSitePlus	TCGA;ICGC;COSMIC	8.808	Down-regulation
CMGC_CDK_CDK5_CDK5_ST	Q13136	PPFIA1	Q00535	CDK5	T701	P702S	702	Missense	proximal	1	no	19.303	7.402	PhosphoSitePlus	TCGA;ICGC;COSMIC	8.808	Loss
CMGC_CDK_CDK5_CDK5_ST	Q13136	PPFIA1	Q00535	CDK5	T701	T701A	701	Missense	central	0	yes	19.303	0.000	PhosphoSitePlus	TCGA;ICGC;COSMIC;GDSC;CCLE	8.808	Loss
CMGC_CDK_CDK5_CDK5_ST	Q13136	PPFIA1	Q00535	CDK5	T701	R703Q	703	Missense	proximal	2	no	19.303	19.164	PhosphoSitePlus	TCGA;ICGC;COSMIC	8.808	Down-regulation
CMGC_CDK_CDK5_CDK5_ST	Q13136	PPFIA1	Q00535	CDK5	S708	E712K	712	Missense	distal	4	no	19.095	19.212	EPSD	TCGA;ICGC;COSMIC	8.808	Up-regulation
CMGC_CDK_CDK5_CDK5_ST	Q13136	PPFIA1	Q00535	CDK5	S708	P702S	702	Missense	distal	-6	no	19.095	19.134	EPSD	TCGA;ICGC;COSMIC	8.808	Up-regulation
CMGC_CDK_CDK5_CDK5_ST	Q13136	PPFIA1	Q00535	CDK5	S708	T701A	701	Missense	distal	-7	no	19.095	19.056	EPSD	TCGA;ICGC;COSMIC;GDSC;CCLE	8.808	Down-regulation
CMGC_CDK_CDK5_CDK5_ST	Q13136	PPFIA1	Q00535	CDK5	S708	R703Q	703	Missense	distal	-5	no	19.095	18.934	EPSD	TCGA;ICGC;COSMIC	8.808	Down-regulation
CMGC_CDK_CDK5_CDK5_ST	Q13136	PPFIA1	Q00535	CDK5	S741	E739K	739	Missense	proximal	-2	no	18.294	18.708	EPSD	TCGA;ICGC;COSMIC	8.808	Up-regulation
CMGC_CDK_CDK5_CDK5_ST	Q13136	PPFIA1	Q00535	CDK5	S741	P746L	746	Missense	distal	5	no	18.294	18.122	EPSD	TCGA;ICGC;COSMIC	8.808	Down-regulation
CMGC_CDK_CDK5_CDK5_ST	Q13136	PPFIA1	Q00535	CDK5	S741	A748S	748	Missense	distal	7	no	18.294	18.305	EPSD	TCGA;ICGC;COSMIC	8.808	Up-regulation
CMGC_CDK_CDK5_CDK5_ST	Q13136	PPFIA1	Q00535	CDK5	S745	E739K	739	Missense	distal	-6	no	18.291	18.421	EPSD	TCGA;ICGC;COSMIC	8.808	Up-regulation
CMGC_CDK_CDK5_CDK5_ST	Q13136	PPFIA1	Q00535	CDK5	S745	P746L	746	Missense	proximal	1	no	18.291	6.341	EPSD	TCGA;ICGC;COSMIC	8.808	Loss
CMGC_CDK_CDK5_CDK5_ST	Q13136	PPFIA1	Q00535	CDK5	S745	L751S	751	Missense	distal	6	no	18.291	18.306	EPSD	TCGA;ICGC;COSMIC	8.808	Up-regulation
CMGC_CDK_CDK5_CDK5_ST	Q13136	PPFIA1	Q00535	CDK5	S745	A748S	748	Missense	distal	3	no	18.291	18.516	EPSD	TCGA;ICGC;COSMIC	8.808	Up-regulation
CMGC_CDK_CDK5_CDK5_ST	Q13136	PPFIA1	Q00535	CDK5	S745	R750W	750	Missense	distal	5	no	18.291	18.114	EPSD	TCGA;ICGC;COSMIC	8.808	Down-regulation
CMGC_CDK_CDK5_CDK5_ST	Q13136	PPFIA1	Q00535	CDK5	S782	G775C	775	Missense	distal	-7	no	8.874	8.854	EPSD	TCGA;ICGC;COSMIC	8.808	Down-regulation
CMGC_CDK_CDK5_CDK5_ST	Q13136	PPFIA1	Q00535	CDK5	S946	S953C	953	Missense	distal	7	no	17.076	17.062	EPSD	TCGA;ICGC;COSMIC	8.808	Down-regulation
CMGC_CDK_CDK5_CDK5_ST	Q13136	PPFIA1	Q00535	CDK5	S953	L957P	957	Missense	distal	4	no	8.850	8.931	EPSD	TCGA;ICGC;COSMIC	8.808	Up-regulation
CMGC_CDK_CDK5_CDK5_ST	Q13136	PPFIA1	Q00535	CDK5	S953	S953C	953	Missense	central	0	yes	8.850	0.000	EPSD	TCGA;ICGC;COSMIC	8.808	Loss
CMGC_CDK_CDK5_CDK5_ST	Q13136	PPFIA1	Q00535	CDK5	S953	T955M	955	Missense	proximal	2	no	8.850	8.652	EPSD	TCGA;ICGC;COSMIC	8.808	Loss
CMGC_CDK_CDK5_CDK5_ST	Q13136	PPFIA1	Q00535	CDK5	S1172	S1174F	1174	Missense	proximal	2	no	17.444	17.234	EPSD	TCGA;ICGC;COSMIC	8.808	Down-regulation
CMGC_CDK_CDK5_CDK5_ST	Q13136	PPFIA1	Q00535	CDK5	S1172	M1170I	1170	Missense	proximal	-2	no	17.444	17.696	EPSD	TCGA;ICGC	8.808	Up-regulation
CMGC_CDK_CDK5_CDK5_ST	Q13136	PPFIA1	Q00535	CDK5	S1172	R1165W	1165	Missense	distal	-7	no	17.444	17.395	EPSD	TCGA;ICGC;COSMIC	8.808	Down-regulation
CMGC_CDK_CDK5_CDK5_ST	Q13136	PPFIA1	Q00535	CDK5	S1172	P1177S	1177	Missense	distal	5	no	17.444	17.457	EPSD	TCGA;ICGC;COSMIC	8.808	Up-regulation
CMGC_CDK_CDK5_CDK5_ST	Q13136	PPFIA1	Q00535	CDK5	S1172	P1177L	1177	Missense	distal	5	no	17.444	17.272	EPSD	TCGA;ICGC;COSMIC	8.808	Down-regulation
CMGC_CDK_CDK5_CDK5_ST	Q13136	PPFIA1	Q00535	CDK5	S1172	T1167S	1167	Missense	distal	-5	no	17.444	17.470	EPSD	TCGA	8.808	Up-regulation
CMGC_CDK_CDK5_CDK5_ST	Q8IWU2	LMTK2	Q00535	CDK5	T90	D88Y	88	Missense	proximal	-2	no	16.399	16.205	EPSD	TCGA;ICGC;COSMIC	8.808	Down-regulation
CMGC_CDK_CDK5_CDK5_ST	Q8IWU2	LMTK2	Q00535	CDK5	S439	P445L	445	Missense	distal	6	no	8.810	8.796	EPSD	TCGA;ICGC;COSMIC	8.808	Loss
CMGC_CDK_CDK5_CDK5_ST	Q8IWU2	LMTK2	Q00535	CDK5	S525	G526R	526	Missense	proximal	1	no	-3.391	9.078	EPSD	TCGA;ICGC;COSMIC	8.808	Gain
CMGC_CDK_CDK5_CDK5_ST	Q8IWU2	LMTK2	Q00535	CDK5	S587	T590P	590	Missense	distal	3	no	8.977	8.441	EPSD	TCGA;ICGC;COSMIC	8.808	Loss
CMGC_CDK_CDK5_CDK5_ST	Q8IWU2	LMTK2	Q00535	CDK5	S587	A591V	591	Missense	distal	4	no	8.977	9.020	EPSD	TCGA;ICGC	8.808	Up-regulation
CMGC_CDK_CDK5_CDK5_ST	Q8IWU2	LMTK2	Q00535	CDK5	S630	E629K	629	Missense	proximal	-1	no	18.284	18.289	EPSD	TCGA;ICGC	8.808	Up-regulation
CMGC_CDK_CDK5_CDK5_ST	Q8IWU2	LMTK2	Q00535	CDK5	S630	F636V	636	Missense	distal	6	no	18.284	18.301	EPSD	TCGA;ICGC;COSMIC	8.808	Up-regulation
CMGC_CDK_CDK5_CDK5_ST	Q8IWU2	LMTK2	Q00535	CDK5	T825	E824K	824	Missense	proximal	-1	no	18.282	18.288	EPSD	TCGA;ICGC;COSMIC	8.808	Up-regulation
CMGC_CDK_CDK5_CDK5_ST	Q8IWU2	LMTK2	Q00535	CDK5	T825	R827L	827	Missense	proximal	2	no	18.282	18.035	EPSD	TCGA;ICGC;COSMIC	8.808	Down-regulation
CMGC_CDK_CDK5_CDK5_ST	Q8IWU2	LMTK2	Q00535	CDK5	T825	V829I	829	Missense	distal	4	no	18.282	18.258	EPSD	TCGA;ICGC;COSMIC	8.808	Down-regulation
CMGC_CDK_CDK5_CDK5_ST	Q8IWU2	LMTK2	Q00535	CDK5	T825	E823K	823	Missense	proximal	-2	no	18.282	18.696	EPSD	TCGA;ICGC;COSMIC	8.808	Up-regulation
CMGC_CDK_CDK5_CDK5_ST	Q8IWU2	LMTK2	Q00535	CDK5	T825	E821K	821	Missense	distal	-4	no	18.282	18.785	EPSD	TCGA;ICGC;COSMIC	8.808	Up-regulation
CMGC_CDK_CDK5_CDK5_ST	Q8IWU2	LMTK2	Q00535	CDK5	T825	R828W	828	Missense	distal	3	no	18.282	16.592	EPSD	TCGA;ICGC	8.808	Down-regulation
CMGC_CDK_CDK5_CDK5_ST	Q8IWU2	LMTK2	Q00535	CDK5	T996	D998G	998	Missense	proximal	2	no	16.692	16.724	EPSD	TCGA;ICGC;COSMIC	8.808	Up-regulation
CMGC_CDK_CDK5_CDK5_ST	Q8IWU2	LMTK2	Q00535	CDK5	T1088	T1091M	1091	Missense	distal	3	no	17.139	15.641	EPSD	TCGA;ICGC;COSMIC	8.808	Down-regulation
CMGC_CDK_CDK5_CDK5_ST	Q8IWU2	LMTK2	Q00535	CDK5	T1088	E1090Q	1090	Missense	proximal	2	no	17.139	17.201	EPSD	TCGA;ICGC;COSMIC	8.808	Up-regulation
CMGC_CDK_CDK5_CDK5_ST	Q8IWU2	LMTK2	Q00535	CDK5	T1088	T1085P	1085	Missense	distal	-3	no	17.139	17.146	EPSD	TCGA;ICGC;COSMIC	8.808	Up-regulation
CMGC_CDK_CDK5_CDK5_ST	Q8IWU2	LMTK2	Q00535	CDK5	S1117	E1118Q	1118	Missense	proximal	1	no	-4.412	8.823	EPSD	TCGA;ICGC;COSMIC	8.808	Gain
CMGC_CDK_CDK5_CDK5_ST	Q8IWU2	LMTK2	Q00535	CDK5	S1124	E1118Q	1118	Missense	distal	-6	no	17.619	17.655	EPSD	TCGA;ICGC;COSMIC	8.808	Up-regulation
CMGC_CDK_CDK5_CDK5_ST	Q8IWU2	LMTK2	Q00535	CDK5	S1124	G1122E	1122	Missense	proximal	-2	no	17.619	17.642	EPSD	TCGA;ICGC;COSMIC	8.808	Up-regulation
CMGC_CDK_CDK5_CDK5_ST	Q8IWU2	LMTK2	Q00535	CDK5	S1124	V1120A	1120	Missense	distal	-4	no	17.619	17.199	EPSD	TCGA;ICGC;COSMIC	8.808	Down-regulation
CMGC_CDK_CDK5_CDK5_ST	Q8IWU2	LMTK2	Q00535	CDK5	S1124	A1127T	1127	Missense	distal	3	no	17.619	18.400	EPSD	TCGA;ICGC;COSMIC	8.808	Up-regulation
CMGC_CDK_CDK5_CDK5_ST	Q8IWU2	LMTK2	Q00535	CDK5	S1323	P1317S	1317	Missense	distal	-6	no	8.852	8.891	EPSD	TCGA;ICGC;COSMIC	8.808	Up-regulation
CMGC_CDK_CDK5_CDK5_ST	Q8IWU2	LMTK2	Q00535	CDK5	S1323	V1318M	1318	Missense	distal	-5	no	8.852	8.626	EPSD	TCGA;ICGC;COSMIC;GDSC;CCLE	8.808	Loss
CMGC_CDK_CDK5_CDK5_ST	Q8IWU2	LMTK2	Q00535	CDK5	S1323	D1326Y	1326	Missense	distal	3	no	8.852	8.698	EPSD	TCGA;ICGC;COSMIC	8.808	Loss
CMGC_CDK_CDK5_CDK5_ST	Q8IWU2	LMTK2	Q00535	CDK5	S1323	G1327V	1327	Missense	distal	4	no	8.852	8.883	EPSD	TCGA;ICGC;COSMIC	8.808	Up-regulation
CMGC_CDK_CDK5_CDK5_ST	Q8IWU2	LMTK2	Q00535	CDK5	S1450	A1455S	1455	Missense	distal	5	no	18.668	18.803	PhosphoSitePlus	TCGA;ICGC;COSMIC	8.808	Up-regulation
CMGC_CDK_CDK5_CDK5_ST	Q8IWU2	LMTK2	Q00535	CDK5	S1450	A1455G	1455	Missense	distal	5	no	18.668	18.699	PhosphoSitePlus	TCGA;ICGC;COSMIC	8.808	Up-regulation
CMGC_CDK_CDK5_CDK5_ST	Q8IWU2	LMTK2	Q00535	CDK5	S1450	P1451A	1451	Missense	proximal	1	no	18.668	7.642	PhosphoSitePlus	TCGA;ICGC;COSMIC	8.808	Loss
CMGC_CDK_CDK5_CDK5_ST	Q8IWU2	LMTK2	Q00535	CDK5	S1450	L1443P	1443	Missense	distal	-7	no	18.668	18.720	PhosphoSitePlus	TCGA;ICGC;COSMIC	8.808	Up-regulation
CMGC_CDK_CDK5_CDK5_ST	Q8IWU2	LMTK2	Q00535	CDK5	S1450	K1447N	1447	Missense	distal	-3	no	18.668	18.616	PhosphoSitePlus	TCGA;ICGC	8.808	Down-regulation
CMGC_CDK_CDK5_CDK5_ST	Q8IWU2	LMTK2	Q00535	CDK5	S1469	A1476T	1476	Missense	distal	7	no	9.433	9.442	EPSD	TCGA;ICGC;COSMIC;GDSC;CCLE	8.808	Up-regulation
CMGC_CDK_CDK5_CDK5_ST	Q8IWU2	LMTK2	Q00535	CDK5	S1469	F1471L	1471	Missense	proximal	2	no	9.433	9.496	EPSD	TCGA;ICGC;COSMIC	8.808	Up-regulation
CMGC_CDK_CDK5_CDK5_ST	Q8IWU2	LMTK2	Q00535	CDK5	T1484	H1485Q	1485	Missense	proximal	1	no	-0.249	9.288	EPSD	TCGA;ICGC	8.808	Gain
CMGC_CDK_CDK5_CDK5_ST	P47989	XDH	Q00535	CDK5	S192	D186Y	186	Missense	distal	-6	no	17.464	17.428	EPSD	TCGA;ICGC;COSMIC	8.808	Down-regulation
CMGC_CDK_CDK5_CDK5_ST	P47989	XDH	Q00535	CDK5	S192	S194F	194	Missense	proximal	2	no	17.464	17.254	EPSD	TCGA;ICGC;COSMIC	8.808	Down-regulation
CMGC_CDK_CDK5_CDK5_ST	P47989	XDH	Q00535	CDK5	S194	S194F	194	Missense	central	0	yes	9.323	0.000	EPSD	TCGA;ICGC;COSMIC	8.808	Loss
CMGC_CDK_CDK5_CDK5_ST	P47989	XDH	Q00535	CDK5	T202	E209K	209	Missense	distal	7	no	16.353	16.369	EPSD	TCGA;ICGC	8.808	Up-regulation
CMGC_CDK_CDK5_CDK5_ST	P47989	XDH	Q00535	CDK5	T222	L216F	216	Missense	distal	-6	no	18.965	18.914	PhosphoSitePlus	TCGA	8.808	Down-regulation
CMGC_CDK_CDK5_CDK5_ST	P47989	XDH	Q00535	CDK5	T222	R228Q	228	Missense	distal	6	no	18.965	18.954	PhosphoSitePlus	TCGA;ICGC;COSMIC	8.808	Down-regulation
CMGC_CDK_CDK5_CDK5_ST	P47989	XDH	Q00535	CDK5	T222	K225E	225	Missense	distal	3	no	18.965	16.678	PhosphoSitePlus	TCGA;ICGC;COSMIC	8.808	Down-regulation
CMGC_CDK_CDK5_CDK5_ST	P47989	XDH	Q00535	CDK5	T222	R224P	224	Missense	proximal	2	no	18.965	18.883	PhosphoSitePlus	TCGA;ICGC;COSMIC	8.808	Down-regulation
CMGC_CDK_CDK5_CDK5_ST	P47989	XDH	Q00535	CDK5	T222	L219P	219	Missense	distal	-3	no	18.965	19.025	PhosphoSitePlus	TCGA;ICGC	8.808	Up-regulation
CMGC_CDK_CDK5_CDK5_ST	P47989	XDH	Q00535	CDK5	S356	G349A	349	Missense	distal	-7	no	17.577	17.576	EPSD	TCGA;ICGC;COSMIC	8.808	Down-regulation
CMGC_CDK_CDK5_CDK5_ST	P47989	XDH	Q00535	CDK5	S356	P357S	357	Missense	proximal	1	no	17.577	5.676	EPSD	TCGA;ICGC;COSMIC	8.808	Loss
CMGC_CDK_CDK5_CDK5_ST	P47989	XDH	Q00535	CDK5	S356	P357L	357	Missense	proximal	1	no	17.577	5.628	EPSD	TCGA;ICGC;COSMIC	8.808	Loss
CMGC_CDK_CDK5_CDK5_ST	P47989	XDH	Q00535	CDK5	S356	S359F	359	Missense	distal	3	no	17.577	16.400	EPSD	TCGA;ICGC;COSMIC	8.808	Down-regulation
CMGC_CDK_CDK5_CDK5_ST	P47989	XDH	Q00535	CDK5	S356	P363L	363	Missense	distal	7	no	17.577	17.565	EPSD	TCGA;ICGC;COSMIC	8.808	Down-regulation
CMGC_CDK_CDK5_CDK5_ST	P47989	XDH	Q00535	CDK5	S356	P363H	363	Missense	distal	7	no	17.577	17.573	EPSD	TCGA;ICGC	8.808	Down-regulation
CMGC_CDK_CDK5_CDK5_ST	P47989	XDH	Q00535	CDK5	S399	L397M	397	Missense	proximal	-2	no	17.108	16.950	EPSD	TCGA;ICGC	8.808	Down-regulation
CMGC_CDK_CDK5_CDK5_ST	P47989	XDH	Q00535	CDK5	S399	G392A	392	Missense	distal	-7	no	17.108	17.106	EPSD	TCGA;ICGC;COSMIC	8.808	Down-regulation
CMGC_CDK_CDK5_CDK5_ST	P47989	XDH	Q00535	CDK5	S399	L404V	404	Missense	distal	5	no	17.108	17.255	EPSD	TCGA;ICGC;COSMIC	8.808	Up-regulation
CMGC_CDK_CDK5_CDK5_ST	P47989	XDH	Q00535	CDK5	T804	R805W	805	Missense	proximal	1	no	8.916	-0.942	EPSD	TCGA;ICGC;COSMIC	8.808	Loss
CMGC_CDK_CDK5_CDK5_ST	P47989	XDH	Q00535	CDK5	T804	G797E	797	Missense	distal	-7	no	8.916	8.923	EPSD	TCGA;ICGC;COSMIC	8.808	Up-regulation
CMGC_CDK_CDK5_CDK5_ST	P47989	XDH	Q00535	CDK5	T804	T804A	804	Missense	central	0	yes	8.916	0.000	EPSD	TCGA;ICGC;COSMIC	8.808	Loss
CMGC_CDK_CDK5_CDK5_ST	P47989	XDH	Q00535	CDK5	T804	T811M	811	Missense	distal	7	no	8.916	8.903	EPSD	TCGA;ICGC;COSMIC	8.808	Down-regulation
CMGC_CDK_CDK5_CDK5_ST	Q12778	FOXO1	Q00535	CDK5	S249	A255T	255	Missense	distal	6	no	18.860	18.872	PhosphoSitePlus	TCGA;ICGC;COSMIC	8.808	Up-regulation
CMGC_CDK_CDK5_CDK5_ST	Q12778	FOXO1	Q00535	CDK5	S249	R251S	251	Missense	proximal	2	no	18.860	18.760	PhosphoSitePlus	TCGA;ICGC;COSMIC	8.808	Down-regulation
CMGC_CDK_CDK5_CDK5_ST	Q12778	FOXO1	Q00535	CDK5	S249	P250L	250	Missense	proximal	1	no	18.860	6.910	PhosphoSitePlus	TCGA;ICGC;COSMIC	8.808	Loss
CMGC_CDK_CDK5_CDK5_ST	Q12778	FOXO1	Q00535	CDK5	S249	P250S	250	Missense	proximal	1	no	18.860	6.959	PhosphoSitePlus	TCGA;ICGC;COSMIC	8.808	Loss
CMGC_CDK_CDK5_CDK5_ST	Q12778	FOXO1	Q00535	CDK5	S249	S249Y	249	Missense	central	0	yes	18.860	0.000	PhosphoSitePlus	TCGA;ICGC;COSMIC	8.808	Loss
CMGC_CDK_CDK5_CDK5_ST	Q12778	FOXO1	Q00535	CDK5	S287	G289E	289	Missense	proximal	2	no	17.004	16.975	EPSD	TCGA;ICGC;COSMIC	8.808	Down-regulation
CMGC_CDK_CDK5_CDK5_ST	Q12778	FOXO1	Q00535	CDK5	S298	P299S	299	Missense	proximal	1	no	18.003	6.102	EPSD	TCGA;ICGC;COSMIC	8.808	Loss
CMGC_CDK_CDK5_CDK5_ST	Q12778	FOXO1	Q00535	CDK5	S329	M332I	332	Missense	distal	3	no	17.354	17.874	EPSD	TCGA;COSMIC	8.808	Up-regulation
CMGC_CDK_CDK5_CDK5_ST	Q12778	FOXO1	Q00535	CDK5	S329	G326R	326	Missense	distal	-3	no	17.354	17.410	EPSD	TCGA;ICGC;COSMIC	8.808	Up-regulation
CMGC_CDK_CDK5_CDK5_ST	Q12778	FOXO1	Q00535	CDK5	S329	S329L	329	Missense	central	0	yes	17.354	0.000	EPSD	TCGA;ICGC;COSMIC	8.808	Loss
CMGC_CDK_CDK5_CDK5_ST	Q12778	FOXO1	Q00535	CDK5	S329	T323A	323	Missense	distal	-6	no	17.354	17.268	EPSD	TCGA;ICGC;COSMIC	8.808	Down-regulation
CMGC_CDK_CDK5_CDK5_ST	Q12778	FOXO1	Q00535	CDK5	S383	L387I	387	Missense	distal	4	no	17.450	17.489	EPSD	TCGA;ICGC;COSMIC	8.808	Up-regulation
CMGC_CDK_CDK5_CDK5_ST	Q12778	FOXO1	Q00535	CDK5	S383	L378I	378	Missense	distal	-5	no	17.450	17.537	EPSD	TCGA;ICGC	8.808	Up-regulation
CMGC_CDK_CDK5_CDK5_ST	Q12778	FOXO1	Q00535	CDK5	S394	L387I	387	Missense	distal	-7	no	18.794	18.817	EPSD	TCGA;ICGC;COSMIC	8.808	Up-regulation
CMGC_CDK_CDK5_CDK5_ST	Q12778	FOXO1	Q00535	CDK5	T402	S406L	406	Missense	distal	4	no	16.071	15.988	EPSD	TCGA;ICGC;COSMIC	8.808	Down-regulation
CMGC_CDK_CDK5_CDK5_ST	Q12778	FOXO1	Q00535	CDK5	T402	A408V	408	Missense	distal	6	no	16.071	16.080	EPSD	TCGA;ICGC;COSMIC	8.808	Up-regulation
CMGC_CDK_CDK5_CDK5_ST	Q12778	FOXO1	Q00535	CDK5	T402	T402M	402	Missense	central	0	yes	16.071	0.000	EPSD	TCGA;ICGC;COSMIC	8.808	Loss
CMGC_CDK_CDK5_CDK5_ST	Q12778	FOXO1	Q00535	CDK5	T402	A408T	408	Missense	distal	6	no	16.071	16.083	EPSD	TCGA;ICGC;COSMIC	8.808	Up-regulation
CMGC_CDK_CDK5_CDK5_ST	Q12778	FOXO1	Q00535	CDK5	S416	L414S	414	Missense	proximal	-2	no	17.205	17.521	EPSD	TCGA;ICGC;COSMIC	8.808	Up-regulation
CMGC_CDK_CDK5_CDK5_ST	Q12778	FOXO1	Q00535	CDK5	S418	L414S	414	Missense	distal	-4	no	16.175	16.995	EPSD	TCGA;ICGC;COSMIC	8.808	Up-regulation
CMGC_CDK_CDK5_CDK5_ST	Q9NZ72	STMN3	Q00535	CDK5	S6	K9N	9	Missense	distal	3	no	8.996	7.063	EPSD	TCGA	8.808	Loss
CMGC_CDK_CDK5_CDK5_ST	Q9NZ72	STMN3	Q00535	CDK5	S60	F54L	54	Missense	distal	-6	no	17.217	17.268	EPSD	TCGA;COSMIC	8.808	Up-regulation
CMGC_CDK_CDK5_CDK5_ST	Q9NZ72	STMN3	Q00535	CDK5	S60	S65F	65	Missense	distal	5	no	17.217	16.977	EPSD	TCGA	8.808	Down-regulation
CMGC_CDK_CDK5_CDK5_ST	Q9NZ72	STMN3	Q00535	CDK5	S65	S65F	65	Missense	central	0	yes	17.890	0.000	EPSD	TCGA	8.808	Loss
CMGC_CDK_CDK5_CDK5_ST	Q9NZ72	STMN3	Q00535	CDK5	S68	P74S	74	Missense	distal	6	no	17.056	17.057	PhosphoSitePlus;EPSD	TCGA;COSMIC	8.808	Up-regulation
CMGC_CDK_CDK5_CDK5_ST	Q9NZ72	STMN3	Q00535	CDK5	S68	S65F	65	Missense	distal	-3	no	17.056	16.979	PhosphoSitePlus;EPSD	TCGA	8.808	Down-regulation
CMGC_CDK_CDK5_CDK5_ST	Q9NZ72	STMN3	Q00535	CDK5	S73	P74S	74	Missense	proximal	1	no	19.380	7.479	EPSD;PhosphoSitePlus	TCGA;COSMIC	8.808	Loss
CMGC_CDK_CDK5_CDK5_ST	O43526	KCNQ2	Q00535	CDK5	S446	R442H	442	Missense	distal	-4	no	18.229	18.009	PhosphoSitePlus	TCGA;COSMIC;GDSC;CCLE	8.808	Down-regulation
CMGC_CDK_CDK5_CDK5_ST	O43526	KCNQ2	Q00535	CDK5	S446	F444L	444	Missense	proximal	-2	no	18.229	18.472	PhosphoSitePlus	TCGA	8.808	Up-regulation
CMGC_CDK_CDK5_CDK5_ST	O43526	KCNQ2	Q00535	CDK5	S457	A460D	460	Missense	distal	3	no	17.610	17.220	EPSD	TCGA;COSMIC	8.808	Down-regulation
CMGC_CDK_CDK5_CDK5_ST	O43526	KCNQ2	Q00535	CDK5	S457	G456R	456	Missense	proximal	-1	no	17.610	17.614	EPSD	TCGA;COSMIC	8.808	Up-regulation
CMGC_CDK_CDK5_CDK5_ST	O43526	KCNQ2	Q00535	CDK5	S466	A460D	460	Missense	distal	-6	no	17.733	17.750	EPSD	TCGA;COSMIC	8.808	Up-regulation
CMGC_CDK_CDK5_CDK5_ST	O43526	KCNQ2	Q00535	CDK5	S466	D470N	470	Missense	distal	4	no	17.733	17.763	EPSD	TCGA;COSMIC	8.808	Up-regulation
CMGC_CDK_CDK5_CDK5_ST	O43526	KCNQ2	Q00535	CDK5	S476	D470N	470	Missense	distal	-6	no	20.140	20.179	EPSD	TCGA;COSMIC	8.808	Up-regulation
CMGC_CDK_CDK5_CDK5_ST	O43526	KCNQ2	Q00535	CDK5	S476	K482Q	482	Missense	distal	6	no	20.140	20.128	EPSD	TCGA;COSMIC	8.808	Down-regulation
CMGC_CDK_CDK5_CDK5_ST	O43526	KCNQ2	Q00535	CDK5	S476	S483N	483	Missense	distal	7	no	20.140	20.136	EPSD	TCGA;COSMIC	8.808	Down-regulation
CMGC_CDK_CDK5_CDK5_ST	O43526	KCNQ2	Q00535	CDK5	S476	E474Q	474	Missense	proximal	-2	no	20.140	20.390	EPSD	TCGA;COSMIC	8.808	Up-regulation
CMGC_CDK_CDK5_CDK5_ST	O43526	KCNQ2	Q00535	CDK5	S476	V480A	480	Missense	distal	4	no	20.140	20.098	EPSD	TCGA;COSMIC	8.808	Down-regulation
CMGC_CDK_CDK5_CDK5_ST	O43526	KCNQ2	Q00535	CDK5	S476	D475N	475	Missense	proximal	-1	no	20.140	20.142	EPSD	TCGA;COSMIC	8.808	Up-regulation
CMGC_CDK_CDK5_CDK5_ST	O43526	KCNQ2	Q00535	CDK5	S503	S503L	503	Missense	central	0	yes	8.905	0.000	EPSD	TCGA;COSMIC	8.808	Loss
CMGC_CDK_CDK5_CDK5_ST	O43526	KCNQ2	Q00535	CDK5	S503	Q505L	505	Missense	proximal	2	no	8.905	8.798	EPSD	TCGA;COSMIC	8.808	Loss
CMGC_CDK_CDK5_CDK5_ST	O43526	KCNQ2	Q00535	CDK5	S503	R497C	497	Missense	distal	-6	no	8.905	8.753	EPSD	TCGA;COSMIC	8.808	Loss
CMGC_CDK_CDK5_CDK5_ST	O43526	KCNQ2	Q00535	CDK5	S503	E508G	508	Missense	distal	5	no	8.905	8.914	EPSD	TCGA;COSMIC	8.808	Up-regulation
CMGC_CDK_CDK5_CDK5_ST	O43526	KCNQ2	Q00535	CDK5	S503	A502V	502	Missense	proximal	-1	no	8.905	8.909	EPSD	TCGA;COSMIC	8.808	Up-regulation
CMGC_CDK_CDK5_CDK5_ST	O43526	KCNQ2	Q00535	CDK5	S503	N506S	506	Missense	distal	3	no	8.905	9.100	EPSD	TCGA	8.808	Up-regulation
CMGC_CDK_CDK5_CDK5_ST	O43526	KCNQ2	Q00535	CDK5	S551	K552N	552	Missense	proximal	1	no	1.744	10.684	EPSD	TCGA	8.808	Gain
CMGC_CDK_CDK5_CDK5_ST	O43526	KCNQ2	Q00535	CDK5	S672	P666L	666	Missense	distal	-6	no	17.031	16.948	EPSD	TCGA;COSMIC	8.808	Down-regulation
CMGC_CDK_CDK5_CDK5_ST	O43526	KCNQ2	Q00535	CDK5	S672	S676R	676	Missense	distal	4	no	17.031	17.048	EPSD	TCGA;ICGC;COSMIC	8.808	Up-regulation
CMGC_CDK_CDK5_CDK5_ST	O43526	KCNQ2	Q00535	CDK5	S672	R677Q	677	Missense	distal	5	no	17.031	16.906	EPSD	TCGA;COSMIC	8.808	Down-regulation
CMGC_CDK_CDK5_CDK5_ST	O43526	KCNQ2	Q00535	CDK5	S672	P668Q	668	Missense	distal	-4	no	17.031	16.906	EPSD	TCGA;COSMIC	8.808	Down-regulation
CMGC_CDK_CDK5_CDK5_ST	Q9UM11	FZR1	Q00535	CDK5	T32	R28W	28	Missense	distal	-4	no	17.556	17.208	EPSD	TCGA;ICGC;COSMIC;GDSC;CCLE	8.808	Down-regulation
CMGC_CDK_CDK5_CDK5_ST	Q9UM11	FZR1	Q00535	CDK5	T32	P33L	33	Missense	proximal	1	no	17.556	5.606	EPSD	TCGA;ICGC;COSMIC	8.808	Loss
CMGC_CDK_CDK5_CDK5_ST	Q9UM11	FZR1	Q00535	CDK5	T32	T32M	32	Missense	central	0	yes	17.556	0.000	EPSD	TCGA;ICGC;COSMIC	8.808	Loss
CMGC_CDK_CDK5_CDK5_ST	Q9UM11	FZR1	Q00535	CDK5	S36	P33L	33	Missense	distal	-3	no	17.598	17.537	EPSD	TCGA;ICGC;COSMIC	8.808	Down-regulation
CMGC_CDK_CDK5_CDK5_ST	Q9UM11	FZR1	Q00535	CDK5	S36	T32M	32	Missense	distal	-4	no	17.598	17.030	EPSD	TCGA;ICGC;COSMIC	8.808	Down-regulation
CMGC_CDK_CDK5_CDK5_ST	Q9UM11	FZR1	Q00535	CDK5	S40	P33L	33	Missense	distal	-7	no	19.875	19.823	PhosphoSitePlus;EPSD	TCGA;ICGC;COSMIC	8.808	Down-regulation
CMGC_CDK_CDK5_CDK5_ST	Q9UM11	FZR1	Q00535	CDK5	T121	R115H	115	Missense	distal	-6	no	19.277	19.211	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	8.808	Down-regulation
CMGC_CDK_CDK5_CDK5_ST	Q9UM11	FZR1	Q00535	CDK5	S138	S137C	137	Missense	proximal	-1	no	16.712	16.705	EPSD	TCGA;ICGC;COSMIC	8.808	Down-regulation
CMGC_CDK_CDK5_CDK5_ST	Q9UM11	FZR1	Q00535	CDK5	S138	D140N	140	Missense	proximal	2	no	16.712	16.771	EPSD	TCGA;ICGC;COSMIC	8.808	Up-regulation
CMGC_CDK_CDK5_CDK5_ST	Q9UM11	FZR1	Q00535	CDK5	S138	D144N	144	Missense	distal	6	no	16.712	16.717	EPSD	TCGA;ICGC;COSMIC;GDSC;CCLE	8.808	Up-regulation
CMGC_CDK_CDK5_CDK5_ST	Q9UM11	FZR1	Q00535	CDK5	S138	S131F	131	Missense	distal	-7	no	16.712	16.627	EPSD	TCGA;ICGC;COSMIC	8.808	Down-regulation
CMGC_CDK_CDK5_CDK5_ST	Q9UM11	FZR1	Q00535	CDK5	S146	P152T	152	Missense	distal	6	no	16.724	16.725	EPSD	TCGA;ICGC;COSMIC	8.808	Up-regulation
CMGC_CDK_CDK5_CDK5_ST	Q9UM11	FZR1	Q00535	CDK5	S146	D140N	140	Missense	distal	-6	no	16.724	16.763	EPSD	TCGA;ICGC;COSMIC	8.808	Up-regulation
CMGC_CDK_CDK5_CDK5_ST	Q9UM11	FZR1	Q00535	CDK5	S146	D144N	144	Missense	proximal	-2	no	16.724	16.846	EPSD	TCGA;ICGC;COSMIC;GDSC;CCLE	8.808	Up-regulation
CMGC_CDK_CDK5_CDK5_ST	Q9UM11	FZR1	Q00535	CDK5	S146	V153I	153	Missense	distal	7	no	16.724	16.721	EPSD	TCGA;ICGC;COSMIC	8.808	Down-regulation
CMGC_CDK_CDK5_CDK5_ST	Q9UM11	FZR1	Q00535	CDK5	S151	P152T	152	Missense	proximal	1	no	17.843	7.355	EPSD	TCGA;ICGC;COSMIC	8.808	Loss
CMGC_CDK_CDK5_CDK5_ST	Q9UM11	FZR1	Q00535	CDK5	S151	D144N	144	Missense	distal	-7	no	17.843	17.861	EPSD	TCGA;ICGC;COSMIC;GDSC;CCLE	8.808	Up-regulation
CMGC_CDK_CDK5_CDK5_ST	Q9UM11	FZR1	Q00535	CDK5	S151	V153I	153	Missense	proximal	2	no	17.843	17.786	EPSD	TCGA;ICGC;COSMIC	8.808	Down-regulation
CMGC_CDK_CDK5_CDK5_ST	Q9UM11	FZR1	Q00535	CDK5	S163	R165Q	165	Missense	proximal	2	no	19.932	19.793	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	8.808	Down-regulation
CMGC_CDK_CDK5_CDK5_ST	Q9UM11	FZR1	Q00535	CDK5	S163	T168S	168	Missense	distal	5	no	19.932	19.933	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	8.808	Up-regulation
CMGC_CDK_CDK5_CDK5_ST	Q9UM11	FZR1	Q00535	CDK5	S163	R162W	162	Missense	proximal	-1	no	19.932	19.928	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	8.808	Down-regulation
CMGC_CDK_CDK5_CDK5_ST	Q9UM11	FZR1	Q00535	CDK5	T300	R307W	307	Missense	distal	7	no	16.244	16.233	EPSD	TCGA	8.808	Down-regulation
CMGC_CDK_CDK5_CDK5_ST	Q9UM11	FZR1	Q00535	CDK5	S346	S343L	343	Missense	distal	-3	no	17.764	17.709	EPSD	TCGA;COSMIC	8.808	Down-regulation
CMGC_CDK_CDK5_CDK5_ST	Q9UM11	FZR1	Q00535	CDK5	T493	L489H	489	Missense	distal	-4	no	9.933	10.071	EPSD	TCGA;COSMIC	8.808	Up-regulation
CMGC_CDK_CDK5_CDK5_ST	P12931	SRC	Q00535	CDK5	S12	S6N	6	Missense	distal	-6	no	12.092	12.033	EPSD	TCGA;ICGC;COSMIC	8.808	Down-regulation
CMGC_CDK_CDK5_CDK5_ST	P12931	SRC	Q00535	CDK5	S12	R14W	14	Missense	proximal	2	no	12.092	11.900	EPSD	TCGA;ICGC;COSMIC	8.808	Down-regulation
CMGC_CDK_CDK5_CDK5_ST	P12931	SRC	Q00535	CDK5	T37	P33S	33	Missense	distal	-4	no	18.064	18.410	EPSD	TCGA;ICGC;COSMIC	8.808	Up-regulation
CMGC_CDK_CDK5_CDK5_ST	P12931	SRC	Q00535	CDK5	T37	S35L	35	Missense	proximal	-2	no	18.064	17.748	EPSD	TCGA;ICGC;COSMIC	8.808	Down-regulation
CMGC_CDK_CDK5_CDK5_ST	P15927	RPA2	Q00535	CDK5	T21	T21P	21	Missense	central	0	yes	8.809	0.000	EPSD	TCGA	8.808	Loss
CMGC_CDK_CDK5_CDK5_ST	P15927	RPA2	Q00535	CDK5	T21	S23F	23	Missense	proximal	2	no	8.809	8.599	EPSD	TCGA;COSMIC	8.808	Loss
CMGC_CDK_CDK5_CDK5_ST	P15927	RPA2	Q00535	CDK5	T21	G19D	19	Missense	proximal	-2	no	8.809	8.940	EPSD	TCGA;COSMIC	8.808	Up-regulation
CMGC_CDK_CDK5_CDK5_ST	P15927	RPA2	Q00535	CDK5	T21	G26S	26	Missense	distal	5	no	8.809	8.913	EPSD	TCGA;COSMIC	8.808	Up-regulation
CMGC_CDK_CDK5_CDK5_ST	P15927	RPA2	Q00535	CDK5	S23	T21P	21	Missense	proximal	-2	no	18.395	18.535	EPSD;PhosphoSitePlus	TCGA	8.808	Up-regulation
CMGC_CDK_CDK5_CDK5_ST	P15927	RPA2	Q00535	CDK5	S23	S23F	23	Missense	central	0	yes	18.395	0.000	EPSD;PhosphoSitePlus	TCGA;COSMIC	8.808	Loss
CMGC_CDK_CDK5_CDK5_ST	P15927	RPA2	Q00535	CDK5	S23	S29L	29	Missense	distal	6	no	18.395	18.380	EPSD;PhosphoSitePlus	TCGA;COSMIC	8.808	Down-regulation
CMGC_CDK_CDK5_CDK5_ST	P15927	RPA2	Q00535	CDK5	S23	G19D	19	Missense	distal	-4	no	18.395	18.560	EPSD;PhosphoSitePlus	TCGA;COSMIC	8.808	Up-regulation
CMGC_CDK_CDK5_CDK5_ST	P15927	RPA2	Q00535	CDK5	S23	G26S	26	Missense	distal	3	no	18.395	18.359	EPSD;PhosphoSitePlus	TCGA;COSMIC	8.808	Down-regulation
CMGC_CDK_CDK5_CDK5_ST	P15927	RPA2	Q00535	CDK5	S29	S23F	23	Missense	distal	-6	no	17.467	17.294	PhosphoSitePlus;EPSD	TCGA;COSMIC	8.808	Down-regulation
CMGC_CDK_CDK5_CDK5_ST	P15927	RPA2	Q00535	CDK5	S29	E36A	36	Missense	distal	7	no	17.467	17.466	PhosphoSitePlus;EPSD	TCGA;COSMIC	8.808	Down-regulation
CMGC_CDK_CDK5_CDK5_ST	P15927	RPA2	Q00535	CDK5	S29	S29L	29	Missense	central	0	yes	17.467	0.000	PhosphoSitePlus;EPSD	TCGA;COSMIC	8.808	Loss
CMGC_CDK_CDK5_CDK5_ST	P15927	RPA2	Q00535	CDK5	S29	G26S	26	Missense	distal	-3	no	17.467	17.508	PhosphoSitePlus;EPSD	TCGA;COSMIC	8.808	Up-regulation
CMGC_CDK_CDK5_CDK5_ST	P15927	RPA2	Q00535	CDK5	S33	E36A	36	Missense	distal	3	no	9.522	9.846	EPSD;PhosphoSitePlus	TCGA;COSMIC	8.808	Up-regulation
CMGC_CDK_CDK5_CDK5_ST	P15927	RPA2	Q00535	CDK5	S33	S29L	29	Missense	distal	-4	no	9.522	8.703	EPSD;PhosphoSitePlus	TCGA;COSMIC	8.808	Loss
CMGC_CDK_CDK5_CDK5_ST	P15927	RPA2	Q00535	CDK5	S33	G26S	26	Missense	distal	-7	no	9.522	9.575	EPSD;PhosphoSitePlus	TCGA;COSMIC	8.808	Up-regulation
CMGC_CDK_CDK5_CDK5_ST	P15927	RPA2	Q00535	CDK5	S33	S39A	39	Missense	distal	6	no	9.522	9.510	EPSD;PhosphoSitePlus	TCGA;COSMIC	8.808	Down-regulation
CMGC_CDK_CDK5_CDK5_ST	P15927	RPA2	Q00535	CDK5	S39	E36A	36	Missense	distal	-3	no	10.639	10.630	EPSD	TCGA;COSMIC	8.808	Down-regulation
CMGC_CDK_CDK5_CDK5_ST	P15927	RPA2	Q00535	CDK5	S39	S39A	39	Missense	central	0	yes	10.639	0.000	EPSD	TCGA;COSMIC	8.808	Loss
CMGC_CDK_CDK5_CDK5_ST	P15927	RPA2	Q00535	CDK5	S39	R42Q	42	Missense	distal	3	no	10.639	8.836	EPSD	TCGA;COSMIC	8.808	Down-regulation
CMGC_CDK_CDK5_CDK5_ST	P15927	RPA2	Q00535	CDK5	S72	G67W	67	Missense	distal	-5	no	9.145	9.138	EPSD	TCGA;COSMIC	8.808	Down-regulation
CMGC_CDK_CDK5_CDK5_ST	O14939	PLD2	Q00535	CDK5	S134	R128Q	128	Missense	distal	-6	no	18.193	18.135	PhosphoSitePlus	TCGA;ICGC;COSMIC	8.808	Down-regulation
CMGC_CDK_CDK5_CDK5_ST	O14939	PLD2	Q00535	CDK5	S134	A136V	136	Missense	proximal	2	no	18.193	18.274	PhosphoSitePlus	TCGA;ICGC;COSMIC	8.808	Up-regulation
CMGC_CDK_CDK5_CDK5_ST	O14939	PLD2	Q00535	CDK5	S134	A130V	130	Missense	distal	-4	no	18.193	18.613	PhosphoSitePlus	TCGA;ICGC;COSMIC	8.808	Up-regulation
CMGC_CDK_CDK5_CDK5_ST	O14939	PLD2	Q00535	CDK5	T156	P152S	152	Missense	distal	-4	no	8.620	8.967	EPSD	TCGA;ICGC	8.808	Gain
CMGC_CDK_CDK5_CDK5_ST	O14939	PLD2	Q00535	CDK5	S493	L499I	499	Missense	distal	6	no	19.277	19.285	EPSD	TCGA;ICGC;COSMIC	8.808	Up-regulation
CMGC_CDK_CDK5_CDK5_ST	O14939	PLD2	Q00535	CDK5	T496	L499I	499	Missense	distal	3	no	16.454	17.084	EPSD	TCGA;ICGC;COSMIC	8.808	Up-regulation
CMGC_CDK_CDK5_CDK5_ST	O14939	PLD2	Q00535	CDK5	S888	L891F	891	Missense	distal	3	no	17.217	17.091	EPSD	TCGA;ICGC;COSMIC	8.808	Down-regulation
CMGC_CDK_CDK5_CDK5_ST	O14939	PLD2	Q00535	CDK5	S888	E882K	882	Missense	distal	-6	no	17.217	17.346	EPSD	TCGA;ICGC;COSMIC	8.808	Up-regulation
CMGC_CDK_CDK5_CDK5_ST	Q05397	PTK2	Q00535	CDK5	T13	H12Y	12	Missense	proximal	-1	no	18.075	18.072	EPSD	TCGA;ICGC;COSMIC	8.808	Down-regulation
CMGC_CDK_CDK5_CDK5_ST	Q05397	PTK2	Q00535	CDK5	T13	P14T	14	Missense	proximal	1	no	18.075	7.588	EPSD	TCGA;ICGC	8.808	Loss
CMGC_CDK_CDK5_CDK5_ST	Q05397	PTK2	Q00535	CDK5	T13	S16L	16	Missense	distal	3	no	18.075	17.023	EPSD	TCGA;ICGC;COSMIC;GDSC;CCLE	8.808	Down-regulation
CMGC_CDK_CDK5_CDK5_ST	Q05397	PTK2	Q00535	CDK5	S17	H12Y	12	Missense	distal	-5	no	9.267	9.110	EPSD	TCGA;ICGC;COSMIC	8.808	Down-regulation
CMGC_CDK_CDK5_CDK5_ST	Q05397	PTK2	Q00535	CDK5	S17	P14T	14	Missense	distal	-3	no	9.267	9.260	EPSD	TCGA;ICGC	8.808	Down-regulation
CMGC_CDK_CDK5_CDK5_ST	Q05397	PTK2	Q00535	CDK5	S17	S16L	16	Missense	proximal	-1	no	9.267	9.261	EPSD	TCGA;ICGC;COSMIC;GDSC;CCLE	8.808	Down-regulation
CMGC_CDK_CDK5_CDK5_ST	Q05397	PTK2	Q00535	CDK5	S29	G31C	31	Missense	proximal	2	no	17.967	17.873	EPSD	TCGA;ICGC;COSMIC	8.808	Down-regulation
CMGC_CDK_CDK5_CDK5_ST	Q05397	PTK2	Q00535	CDK5	S248	F243L	243	Missense	distal	-5	no	15.944	16.054	EPSD	TCGA;ICGC	8.808	Up-regulation
CMGC_CDK_CDK5_CDK5_ST	Q05397	PTK2	Q00535	CDK5	S248	E245D	245	Missense	distal	-3	no	15.944	15.942	EPSD	TCGA;ICGC;COSMIC	8.808	Down-regulation
CMGC_CDK_CDK5_CDK5_ST	Q05397	PTK2	Q00535	CDK5	S443	A448T	448	Missense	distal	5	no	16.344	16.478	EPSD	TCGA;ICGC;COSMIC	8.808	Up-regulation
CMGC_CDK_CDK5_CDK5_ST	Q05397	PTK2	Q00535	CDK5	S443	V436I	436	Missense	distal	-7	no	16.344	16.328	EPSD	TCGA;ICGC;COSMIC	8.808	Down-regulation
CMGC_CDK_CDK5_CDK5_ST	Q05397	PTK2	Q00535	CDK5	S443	A450V	450	Missense	distal	7	no	16.344	16.351	EPSD	TCGA;ICGC;COSMIC	8.808	Up-regulation
CMGC_CDK_CDK5_CDK5_ST	Q05397	PTK2	Q00535	CDK5	S443	A448D	448	Missense	distal	5	no	16.344	16.345	EPSD	TCGA;ICGC;COSMIC	8.808	Up-regulation
CMGC_CDK_CDK5_CDK5_ST	Q05397	PTK2	Q00535	CDK5	S716	P718L	718	Missense	proximal	2	no	8.899	8.733	EPSD	TCGA;ICGC;COSMIC	8.808	Loss
CMGC_CDK_CDK5_CDK5_ST	Q05397	PTK2	Q00535	CDK5	S716	P723L	723	Missense	distal	7	no	8.899	8.887	EPSD	TCGA;ICGC;COSMIC	8.808	Down-regulation
CMGC_CDK_CDK5_CDK5_ST	Q05397	PTK2	Q00535	CDK5	S716	K714N	714	Missense	proximal	-2	no	8.899	8.715	EPSD	TCGA;ICGC;COSMIC	8.808	Loss
CMGC_CDK_CDK5_CDK5_ST	Q05397	PTK2	Q00535	CDK5	S722	S725F	725	Missense	distal	3	no	17.684	16.507	EPSD	TCGA;ICGC	8.808	Down-regulation
CMGC_CDK_CDK5_CDK5_ST	Q05397	PTK2	Q00535	CDK5	S722	P718L	718	Missense	distal	-4	no	17.684	17.211	EPSD	TCGA;ICGC;COSMIC	8.808	Down-regulation
CMGC_CDK_CDK5_CDK5_ST	Q05397	PTK2	Q00535	CDK5	S722	P723L	723	Missense	proximal	1	no	17.684	5.734	EPSD	TCGA;ICGC;COSMIC	8.808	Loss
CMGC_CDK_CDK5_CDK5_ST	Q05397	PTK2	Q00535	CDK5	S732	S725F	725	Missense	distal	-7	no	17.875	17.791	EPSD	TCGA;ICGC	8.808	Down-regulation
CMGC_CDK_CDK5_CDK5_ST	Q05397	PTK2	Q00535	CDK5	S840	R841Q	841	Missense	proximal	1	no	8.909	8.880	EPSD	TCGA;ICGC;COSMIC;GDSC	8.808	Down-regulation
CMGC_CDK_CDK5_CDK5_ST	P10275	AR	Q00535	CDK5	S16	K17N	17	Missense	proximal	1	no	0.772	9.711	EPSD	TCGA;ICGC;COSMIC	8.808	Gain
CMGC_CDK_CDK5_CDK5_ST	P10275	AR	Q00535	CDK5	S96	G95S	95	Missense	proximal	-1	no	17.005	17.010	EPSD	TCGA;ICGC;COSMIC	8.808	Up-regulation
CMGC_CDK_CDK5_CDK5_ST	P10275	AR	Q00535	CDK5	S96	E93D	93	Missense	distal	-3	no	17.005	17.003	EPSD	TCGA;ICGC;COSMIC	8.808	Down-regulation
CMGC_CDK_CDK5_CDK5_ST	P10275	AR	Q00535	CDK5	S258	R264W	264	Missense	distal	6	no	15.761	15.744	EPSD	TCGA;ICGC;COSMIC	8.808	Down-regulation
CMGC_CDK_CDK5_CDK5_ST	P10275	AR	Q00535	CDK5	S258	A253V	253	Missense	distal	-5	no	15.761	15.887	EPSD	TCGA;ICGC;COSMIC	8.808	Up-regulation
CMGC_CDK_CDK5_CDK5_ST	P10275	AR	Q00535	CDK5	T282	E289K	289	Missense	distal	7	no	17.057	17.073	EPSD	TCGA;ICGC;COSMIC	8.808	Up-regulation
CMGC_CDK_CDK5_CDK5_ST	P10275	AR	Q00535	CDK5	T282	R280C	280	Missense	proximal	-2	no	17.057	16.541	EPSD	TCGA;ICGC;COSMIC	8.808	Down-regulation
CMGC_CDK_CDK5_CDK5_ST	P10275	AR	Q00535	CDK5	S298	A299T	299	Missense	proximal	1	no	8.738	9.278	EPSD	TCGA;ICGC;COSMIC	8.808	Gain
CMGC_CDK_CDK5_CDK5_ST	P10275	AR	Q00535	CDK5	S310	E308K	308	Missense	proximal	-2	no	19.095	19.508	PhosphoSitePlus;EPSD	TCGA;COSMIC	8.808	Up-regulation
CMGC_CDK_CDK5_CDK5_ST	P10275	AR	Q00535	CDK5	S310	Y316H	316	Missense	distal	6	no	19.095	19.106	PhosphoSitePlus;EPSD	TCGA;ICGC	8.808	Up-regulation
CMGC_CDK_CDK5_CDK5_ST	P10275	AR	Q00535	CDK5	S516	P513S	513	Missense	distal	-3	no	17.169	17.163	EPSD	TCGA;ICGC;COSMIC	8.808	Down-regulation
CMGC_CDK_CDK5_CDK5_ST	P10275	AR	Q00535	CDK5	S651	E645K	645	Missense	distal	-6	no	17.918	18.048	EPSD	TCGA;ICGC;COSMIC	8.808	Up-regulation
CMGC_CDK_CDK5_CDK5_ST	O94811	TPPP	Q00535	CDK5	T14	R13M	13	Missense	proximal	-1	no	20.417	20.411	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	8.808	Down-regulation
CMGC_CDK_CDK5_CDK5_ST	O94811	TPPP	Q00535	CDK5	S18	R13M	13	Missense	distal	-5	no	19.174	18.810	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	8.808	Down-regulation
CMGC_CDK_CDK5_CDK5_ST	O94811	TPPP	Q00535	CDK5	S45	A50V	50	Missense	distal	5	no	15.499	15.596	EPSD	TCGA;ICGC;COSMIC	8.808	Up-regulation
CMGC_CDK_CDK5_CDK5_ST	O94811	TPPP	Q00535	CDK5	S45	L48F	48	Missense	distal	3	no	15.499	15.373	EPSD	TCGA;ICGC;COSMIC	8.808	Down-regulation
CMGC_CDK_CDK5_CDK5_ST	O94811	TPPP	Q00535	CDK5	S160	S159L	159	Missense	proximal	-1	no	18.510	18.504	PhosphoSitePlus;EPSD	TCGA;ICGC;COSMIC	8.808	Down-regulation
CMGC_CDK_CDK5_CDK5_ST	O94811	TPPP	Q00535	CDK5	S164	S159L	159	Missense	distal	-5	no	9.997	9.777	EPSD	TCGA;ICGC;COSMIC	8.808	Down-regulation
CMGC_CDK_CDK5_CDK5_ST	P37231	PPARG	Q00535	CDK5	S112	S117Y	117	Missense	distal	5	no	17.396	17.219	EPSD	TCGA	8.808	Down-regulation
CMGC_CDK_CDK5_CDK5_ST	P37231	PPARG	Q00535	CDK5	S273	M280T	280	Missense	distal	7	no	17.838	17.851	PhosphoSitePlus	TCGA;COSMIC	8.808	Up-regulation
CMGC_CDK_CDK5_CDK5_ST	P37231	PPARG	Q00535	CDK5	S273	G267E	267	Missense	distal	-6	no	17.838	17.846	PhosphoSitePlus	TCGA	8.808	Up-regulation
CMGC_CDK_CDK5_CDK5_ST	Q9Y210	TRPC6	Q00535	CDK5	S195	E188Q	188	Missense	distal	-7	no	17.799	17.824	EPSD	TCGA;ICGC;COSMIC	8.808	Up-regulation
CMGC_CDK_CDK5_CDK5_ST	Q9Y210	TRPC6	Q00535	CDK5	S195	Q202K	202	Missense	distal	7	no	17.799	17.809	EPSD	TCGA;ICGC;COSMIC	8.808	Up-regulation
CMGC_CDK_CDK5_CDK5_ST	Q9Y210	TRPC6	Q00535	CDK5	S195	Q198K	198	Missense	distal	3	no	17.799	19.921	EPSD	TCGA;ICGC;COSMIC	8.808	Up-regulation
CMGC_CDK_CDK5_CDK5_ST	Q9Y210	TRPC6	Q00535	CDK5	S195	K190E	190	Missense	distal	-5	no	17.799	17.509	EPSD	TCGA;ICGC;COSMIC	8.808	Down-regulation
CMGC_CDK_CDK5_CDK5_ST	Q9Y210	TRPC6	Q00535	CDK5	S270	Y277C	277	Missense	distal	7	no	11.090	11.088	EPSD	TCGA;ICGC;COSMIC	8.808	Down-regulation
CMGC_CDK_CDK5_CDK5_ST	Q9Y210	TRPC6	Q00535	CDK5	S270	S266L	266	Missense	distal	-4	no	11.090	10.270	EPSD	TCGA;ICGC;COSMIC	8.808	Down-regulation
CMGC_CDK_CDK5_CDK5_ST	Q9Y210	TRPC6	Q00535	CDK5	S270	I274M	274	Missense	distal	4	no	11.090	11.038	EPSD	TCGA;ICGC;COSMIC	8.808	Down-regulation
CMGC_CDK_CDK5_CDK5_ST	Q9Y210	TRPC6	Q00535	CDK5	S272	Y277C	277	Missense	distal	5	no	9.508	9.492	EPSD	TCGA;ICGC;COSMIC	8.808	Down-regulation
CMGC_CDK_CDK5_CDK5_ST	Q9Y210	TRPC6	Q00535	CDK5	S272	H269N	269	Missense	distal	-3	no	9.508	9.507	EPSD	TCGA;ICGC;COSMIC	8.808	Down-regulation
CMGC_CDK_CDK5_CDK5_ST	Q9Y210	TRPC6	Q00535	CDK5	S272	S266L	266	Missense	distal	-6	no	9.508	9.386	EPSD	TCGA;ICGC;COSMIC	8.808	Down-regulation
CMGC_CDK_CDK5_CDK5_ST	Q9Y210	TRPC6	Q00535	CDK5	S272	I274M	274	Missense	proximal	2	no	9.508	9.405	EPSD	TCGA;ICGC;COSMIC	8.808	Down-regulation
CMGC_CDK_CDK5_CDK5_ST	Q9Y210	TRPC6	Q00535	CDK5	S282	P283T	283	Missense	proximal	1	no	17.661	7.173	EPSD	TCGA;ICGC;COSMIC	8.808	Loss
CMGC_CDK_CDK5_CDK5_ST	Q9Y210	TRPC6	Q00535	CDK5	S282	Y277C	277	Missense	distal	-5	no	17.661	17.636	EPSD	TCGA;ICGC;COSMIC	8.808	Down-regulation
CMGC_CDK_CDK5_CDK5_ST	Q9Y210	TRPC6	Q00535	CDK5	S282	P283S	283	Missense	proximal	1	no	17.661	5.760	EPSD	TCGA;ICGC;COSMIC	8.808	Loss
CMGC_CDK_CDK5_CDK5_ST	Q9Y210	TRPC6	Q00535	CDK5	S282	S282I	282	Missense	central	0	yes	17.661	0.000	EPSD	TCGA;ICGC;COSMIC	8.808	Loss
CMGC_CDK_CDK5_CDK5_ST	Q9Y210	TRPC6	Q00535	CDK5	S769	S769I	769	Missense	central	0	yes	17.871	0.000	EPSD	TCGA;ICGC;COSMIC	8.808	Loss
CMGC_CDK_CDK5_CDK5_ST	Q9NXR1	NDE1	Q00535	CDK5	S4	G5R	5	Missense	proximal	1	no	-2.984	9.485	EPSD	TCGA;ICGC;COSMIC	8.808	Gain
CMGC_CDK_CDK5_CDK5_ST	Q9NXR1	NDE1	Q00535	CDK5	T191	P192H	192	Missense	proximal	1	no	16.727	-1.785	PhosphoSitePlus	TCGA;ICGC;COSMIC	8.808	Loss
CMGC_CDK_CDK5_CDK5_ST	Q9NXR1	NDE1	Q00535	CDK5	T215	S211F	211	Missense	distal	-4	no	17.185	16.024	EPSD	TCGA;ICGC;COSMIC	8.808	Down-regulation
CMGC_CDK_CDK5_CDK5_ST	Q9NXR1	NDE1	Q00535	CDK5	T228	S224L	224	Missense	distal	-4	no	17.529	16.710	EPSD	TCGA;ICGC;COSMIC	8.808	Down-regulation
CMGC_CDK_CDK5_CDK5_ST	Q9NXR1	NDE1	Q00535	CDK5	T228	S223G	223	Missense	distal	-5	no	17.529	17.358	EPSD	TCGA;ICGC;COSMIC	8.808	Down-regulation
CMGC_CDK_CDK5_CDK5_ST	Q9NXR1	NDE1	Q00535	CDK5	T243	R250W	250	Missense	distal	7	no	17.944	17.933	EPSD	TCGA;ICGC;COSMIC	8.808	Down-regulation
CMGC_CDK_CDK5_CDK5_ST	Q9NXR1	NDE1	Q00535	CDK5	T243	T240A	240	Missense	distal	-3	no	17.944	17.899	EPSD	TCGA;ICGC;COSMIC	8.808	Down-regulation
CMGC_CDK_CDK5_CDK5_ST	Q9NXR1	NDE1	Q00535	CDK5	T243	L245F	245	Missense	proximal	2	no	17.944	17.882	EPSD	TCGA;ICGC;COSMIC	8.808	Down-regulation
CMGC_CDK_CDK5_CDK5_ST	Q9NXR1	NDE1	Q00535	CDK5	T243	T246I	246	Missense	distal	3	no	17.944	16.966	EPSD	TCGA;ICGC;COSMIC	8.808	Down-regulation
CMGC_CDK_CDK5_CDK5_ST	Q9NXR1	NDE1	Q00535	CDK5	T246	R250W	250	Missense	distal	4	no	16.791	16.719	EPSD	TCGA;ICGC;COSMIC	8.808	Down-regulation
CMGC_CDK_CDK5_CDK5_ST	Q9NXR1	NDE1	Q00535	CDK5	T246	T240A	240	Missense	distal	-6	no	16.791	16.704	EPSD	TCGA;ICGC;COSMIC	8.808	Down-regulation
CMGC_CDK_CDK5_CDK5_ST	Q9NXR1	NDE1	Q00535	CDK5	T246	L245F	245	Missense	proximal	-1	no	16.791	16.788	EPSD	TCGA;ICGC;COSMIC	8.808	Down-regulation
CMGC_CDK_CDK5_CDK5_ST	Q9NXR1	NDE1	Q00535	CDK5	T246	T246I	246	Missense	central	0	yes	16.791	0.000	EPSD	TCGA;ICGC;COSMIC	8.808	Loss
CMGC_CDK_CDK5_CDK5_ST	P04637	TP53	Q00535	CDK5	S33	P27S	27	Missense	distal	-6	no	17.666	17.705	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	8.808	Up-regulation
CMGC_CDK_CDK5_CDK5_ST	P04637	TP53	Q00535	CDK5	S33	P27L	27	Missense	distal	-6	no	17.666	17.583	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC;GDSC;CCLE	8.808	Down-regulation
CMGC_CDK_CDK5_CDK5_ST	P04637	TP53	Q00535	CDK5	S46	D48N	48	Missense	proximal	2	no	17.016	17.076	PhosphoSitePlus;EPSD	TCGA;ICGC;COSMIC;GDSC;CCLE	8.808	Up-regulation
CMGC_CDK_CDK5_CDK5_ST	P04637	TP53	Q00535	CDK5	T81	A79V	79	Missense	proximal	-2	no	16.829	17.025	EPSD	TCGA;ICGC;COSMIC	8.808	Up-regulation
CMGC_CDK_CDK5_CDK5_ST	P04637	TP53	Q00535	CDK5	T81	P77L	77	Missense	distal	-4	no	16.829	16.356	EPSD	TCGA;ICGC;COSMIC	8.808	Down-regulation
CMGC_CDK_CDK5_CDK5_ST	P04637	TP53	Q00535	CDK5	T81	P82L	82	Missense	proximal	1	no	16.829	4.879	EPSD	TCGA;ICGC;COSMIC	8.808	Loss
CMGC_CDK_CDK5_CDK5_ST	P04637	TP53	Q00535	CDK5	T81	A74T	74	Missense	distal	-7	no	16.829	16.868	EPSD	TCGA;ICGC;COSMIC	8.808	Up-regulation
CMGC_CDK_CDK5_CDK5_ST	P04637	TP53	Q00535	CDK5	S99	G105C	105	Missense	distal	6	no	10.461	10.455	EPSD	TCGA;ICGC;COSMIC;GDSC	8.808	Down-regulation
CMGC_CDK_CDK5_CDK5_ST	P04637	TP53	Q00535	CDK5	S99	S106R	106	Missense	distal	7	no	10.461	10.463	EPSD	TCGA;ICGC;COSMIC;GDSC;CCLE	8.808	Up-regulation
CMGC_CDK_CDK5_CDK5_ST	P04637	TP53	Q00535	CDK5	S99	G105R	105	Missense	distal	6	no	10.461	10.478	EPSD	TCGA;ICGC;COSMIC;CCLE	8.808	Up-regulation
CMGC_CDK_CDK5_CDK5_ST	P04637	TP53	Q00535	CDK5	S99	G105V	105	Missense	distal	6	no	10.461	10.468	EPSD	TCGA;ICGC;COSMIC	8.808	Up-regulation
CMGC_CDK_CDK5_CDK5_ST	P04637	TP53	Q00535	CDK5	S99	G105D	105	Missense	distal	6	no	10.461	10.460	EPSD	TCGA;ICGC;COSMIC	8.808	Down-regulation
CMGC_CDK_CDK5_CDK5_ST	P04637	TP53	Q00535	CDK5	S99	G105S	105	Missense	distal	6	no	10.461	10.471	EPSD	TCGA;ICGC;COSMIC	8.808	Up-regulation
CMGC_CDK_CDK5_CDK5_ST	P04637	TP53	Q00535	CDK5	S99	V97D	97	Missense	proximal	-2	no	10.461	10.308	EPSD	TCGA;ICGC;COSMIC	8.808	Down-regulation
CMGC_CDK_CDK5_CDK5_ST	P04637	TP53	Q00535	CDK5	S99	P92S	92	Missense	distal	-7	no	10.461	10.466	EPSD	TCGA;ICGC	8.808	Up-regulation
CMGC_CDK_CDK5_CDK5_ST	P04637	TP53	Q00535	CDK5	S127	K132N	132	Missense	distal	5	no	16.799	16.597	EPSD	TCGA;ICGC;COSMIC;GDSC;CCLE	8.808	Down-regulation
CMGC_CDK_CDK5_CDK5_ST	P04637	TP53	Q00535	CDK5	S127	S121Y	121	Missense	distal	-6	no	16.799	16.666	EPSD	TCGA;ICGC;COSMIC	8.808	Down-regulation
CMGC_CDK_CDK5_CDK5_ST	P04637	TP53	Q00535	CDK5	S127	M133K	133	Missense	distal	6	no	16.799	16.825	EPSD	TCGA;ICGC;COSMIC;CCLE	8.808	Up-regulation
CMGC_CDK_CDK5_CDK5_ST	P04637	TP53	Q00535	CDK5	S127	K132E	132	Missense	distal	5	no	16.799	16.548	EPSD	TCGA;ICGC;COSMIC;GDSC;CCLE	8.808	Down-regulation
CMGC_CDK_CDK5_CDK5_ST	P04637	TP53	Q00535	CDK5	S127	S127P	127	Missense	central	0	yes	16.799	0.000	EPSD	TCGA;ICGC;COSMIC;GDSC;CCLE	8.808	Loss
CMGC_CDK_CDK5_CDK5_ST	P04637	TP53	Q00535	CDK5	S127	Y126N	126	Missense	proximal	-1	no	16.799	16.803	EPSD	TCGA;ICGC;COSMIC	8.808	Up-regulation
CMGC_CDK_CDK5_CDK5_ST	P04637	TP53	Q00535	CDK5	S127	L130V	130	Missense	distal	3	no	16.799	17.878	EPSD	TCGA;ICGC;COSMIC;GDSC;CCLE	8.808	Up-regulation
CMGC_CDK_CDK5_CDK5_ST	P04637	TP53	Q00535	CDK5	S127	K132T	132	Missense	distal	5	no	16.799	16.661	EPSD	TCGA;ICGC;COSMIC;GDSC;CCLE	8.808	Down-regulation
CMGC_CDK_CDK5_CDK5_ST	P04637	TP53	Q00535	CDK5	S127	S127Y	127	Missense	central	0	yes	16.799	0.000	EPSD	TCGA;ICGC;COSMIC	8.808	Loss
CMGC_CDK_CDK5_CDK5_ST	P04637	TP53	Q00535	CDK5	S127	S127F	127	Missense	central	0	yes	16.799	0.000	EPSD	TCGA;ICGC;COSMIC;CCLE	8.808	Loss
CMGC_CDK_CDK5_CDK5_ST	P04637	TP53	Q00535	CDK5	S127	M133R	133	Missense	distal	6	no	16.799	16.823	EPSD	TCGA;ICGC;COSMIC	8.808	Up-regulation
CMGC_CDK_CDK5_CDK5_ST	P04637	TP53	Q00535	CDK5	S127	K132R	132	Missense	distal	5	no	16.799	16.724	EPSD	TCGA;ICGC;COSMIC;GDSC;CCLE	8.808	Down-regulation
CMGC_CDK_CDK5_CDK5_ST	P04637	TP53	Q00535	CDK5	S127	F134L	134	Missense	distal	7	no	16.799	16.804	EPSD	TCGA;ICGC;COSMIC;CCLE	8.808	Up-regulation
CMGC_CDK_CDK5_CDK5_ST	P04637	TP53	Q00535	CDK5	S127	Y126S	126	Missense	proximal	-1	no	16.799	16.806	EPSD	TCGA;ICGC;COSMIC	8.808	Up-regulation
CMGC_CDK_CDK5_CDK5_ST	P04637	TP53	Q00535	CDK5	S127	L130P	130	Missense	distal	3	no	16.799	17.871	EPSD	TCGA;ICGC;COSMIC	8.808	Up-regulation
CMGC_CDK_CDK5_CDK5_ST	P04637	TP53	Q00535	CDK5	S127	L130F	130	Missense	distal	3	no	16.799	16.673	EPSD	TCGA;ICGC;COSMIC;CCLE	8.808	Down-regulation
CMGC_CDK_CDK5_CDK5_ST	P04637	TP53	Q00535	CDK5	S127	F134V	134	Missense	distal	7	no	16.799	16.814	EPSD	TCGA;ICGC;COSMIC	8.808	Up-regulation
CMGC_CDK_CDK5_CDK5_ST	P04637	TP53	Q00535	CDK5	S127	T125M	125	Missense	proximal	-2	no	16.799	16.366	EPSD	TCGA;ICGC;COSMIC;GDSC	8.808	Down-regulation
CMGC_CDK_CDK5_CDK5_ST	P04637	TP53	Q00535	CDK5	S127	Y126D	126	Missense	proximal	-1	no	16.799	16.801	EPSD	TCGA;ICGC;COSMIC;GDSC	8.808	Up-regulation
CMGC_CDK_CDK5_CDK5_ST	P04637	TP53	Q00535	CDK5	S127	K120E	120	Missense	distal	-7	no	16.799	16.736	EPSD	TCGA;ICGC;COSMIC	8.808	Down-regulation
CMGC_CDK_CDK5_CDK5_ST	P04637	TP53	Q00535	CDK5	S127	N131S	131	Missense	distal	4	no	16.799	16.830	EPSD	TCGA;ICGC;COSMIC	8.808	Up-regulation
CMGC_CDK_CDK5_CDK5_ST	P04637	TP53	Q00535	CDK5	S127	T125P	125	Missense	proximal	-2	no	16.799	16.939	EPSD	TCGA;ICGC;COSMIC;CCLE	8.808	Up-regulation
CMGC_CDK_CDK5_CDK5_ST	P04637	TP53	Q00535	CDK5	S127	S127C	127	Missense	central	0	yes	16.799	0.000	EPSD	TCGA;ICGC;COSMIC;CCLE	8.808	Loss
CMGC_CDK_CDK5_CDK5_ST	P04637	TP53	Q00535	CDK5	S127	N131I	131	Missense	distal	4	no	16.799	16.786	EPSD	TCGA;ICGC;COSMIC	8.808	Down-regulation
CMGC_CDK_CDK5_CDK5_ST	P04637	TP53	Q00535	CDK5	S127	Y126H	126	Missense	proximal	-1	no	16.799	16.803	EPSD	TCGA;ICGC;COSMIC;GDSC	8.808	Up-regulation
CMGC_CDK_CDK5_CDK5_ST	P04637	TP53	Q00535	CDK5	S127	K132Q	132	Missense	distal	5	no	16.799	16.599	EPSD	TCGA;ICGC;COSMIC;GDSC;CCLE	8.808	Down-regulation
CMGC_CDK_CDK5_CDK5_ST	P04637	TP53	Q00535	CDK5	S127	L130R	130	Missense	distal	3	no	16.799	19.269	EPSD	TCGA;ICGC;COSMIC;CCLE	8.808	Up-regulation
CMGC_CDK_CDK5_CDK5_ST	P04637	TP53	Q00535	CDK5	T150	W146S	146	Missense	distal	-4	no	16.442	17.252	EPSD	TCGA;ICGC;COSMIC	8.808	Up-regulation
CMGC_CDK_CDK5_CDK5_ST	P04637	TP53	Q00535	CDK5	T150	P152L	152	Missense	proximal	2	no	16.442	16.277	EPSD	TCGA;ICGC;COSMIC;GDSC;CCLE	8.808	Down-regulation
CMGC_CDK_CDK5_CDK5_ST	P04637	TP53	Q00535	CDK5	T150	D148N	148	Missense	proximal	-2	no	16.442	16.564	EPSD	TCGA;ICGC;COSMIC	8.808	Up-regulation
CMGC_CDK_CDK5_CDK5_ST	P04637	TP53	Q00535	CDK5	T150	P151H	151	Missense	proximal	1	no	16.442	-2.070	EPSD	TCGA;ICGC;COSMIC;GDSC;CCLE	8.808	Loss
CMGC_CDK_CDK5_CDK5_ST	P04637	TP53	Q00535	CDK5	T150	P151A	151	Missense	proximal	1	no	16.442	5.416	EPSD	TCGA;ICGC;COSMIC;CCLE	8.808	Loss
CMGC_CDK_CDK5_CDK5_ST	P04637	TP53	Q00535	CDK5	T150	R156P	156	Missense	distal	6	no	16.442	16.434	EPSD	TCGA;ICGC;COSMIC;GDSC;CCLE	8.808	Down-regulation
CMGC_CDK_CDK5_CDK5_ST	P04637	TP53	Q00535	CDK5	T150	V143A	143	Missense	distal	-7	no	16.442	16.406	EPSD	TCGA;ICGC;COSMIC;GDSC;CCLE	8.808	Down-regulation
CMGC_CDK_CDK5_CDK5_ST	P04637	TP53	Q00535	CDK5	T150	P151S	151	Missense	proximal	1	no	16.442	4.541	EPSD	TCGA;ICGC;COSMIC;GDSC;CCLE	8.808	Loss
CMGC_CDK_CDK5_CDK5_ST	P04637	TP53	Q00535	CDK5	T150	V157F	157	Missense	distal	7	no	16.442	16.427	EPSD	TCGA;ICGC;COSMIC;GDSC;CCLE	8.808	Down-regulation
CMGC_CDK_CDK5_CDK5_ST	P04637	TP53	Q00535	CDK5	T150	V157G	157	Missense	distal	7	no	16.442	16.435	EPSD	TCGA;ICGC;COSMIC	8.808	Down-regulation
CMGC_CDK_CDK5_CDK5_ST	P04637	TP53	Q00535	CDK5	T150	V157D	157	Missense	distal	7	no	16.442	16.436	EPSD	TCGA;ICGC;COSMIC	8.808	Down-regulation
CMGC_CDK_CDK5_CDK5_ST	P04637	TP53	Q00535	CDK5	T150	L145R	145	Missense	distal	-5	no	16.442	16.742	EPSD	TCGA;ICGC;COSMIC;GDSC;CCLE	8.808	Up-regulation
CMGC_CDK_CDK5_CDK5_ST	P04637	TP53	Q00535	CDK5	T150	T155I	155	Missense	distal	5	no	16.442	16.353	EPSD	TCGA;ICGC;COSMIC;CCLE	8.808	Down-regulation
CMGC_CDK_CDK5_CDK5_ST	P04637	TP53	Q00535	CDK5	T150	V143M	143	Missense	distal	-7	no	16.442	16.388	EPSD	TCGA;ICGC;COSMIC;GDSC;CCLE	8.808	Down-regulation
CMGC_CDK_CDK5_CDK5_ST	P04637	TP53	Q00535	CDK5	T150	T155N	155	Missense	distal	5	no	16.442	16.378	EPSD	TCGA;ICGC;COSMIC;GDSC;CCLE	8.808	Down-regulation
CMGC_CDK_CDK5_CDK5_ST	P04637	TP53	Q00535	CDK5	T150	P152S	152	Missense	proximal	2	no	16.442	16.424	EPSD	TCGA;ICGC;COSMIC;CCLE	8.808	Down-regulation
CMGC_CDK_CDK5_CDK5_ST	P04637	TP53	Q00535	CDK5	T150	R156C	156	Missense	distal	6	no	16.442	16.419	EPSD	TCGA;ICGC;COSMIC	8.808	Down-regulation
CMGC_CDK_CDK5_CDK5_ST	P04637	TP53	Q00535	CDK5	T150	P151T	151	Missense	proximal	1	no	16.442	5.955	EPSD	TCGA;ICGC;COSMIC	8.808	Loss
CMGC_CDK_CDK5_CDK5_ST	P04637	TP53	Q00535	CDK5	T150	T155P	155	Missense	distal	5	no	16.442	16.430	EPSD	TCGA;ICGC;COSMIC;CCLE	8.808	Down-regulation
CMGC_CDK_CDK5_CDK5_ST	P04637	TP53	Q00535	CDK5	T150	V143G	143	Missense	distal	-7	no	16.442	16.408	EPSD	TCGA;ICGC;COSMIC	8.808	Down-regulation
CMGC_CDK_CDK5_CDK5_ST	P04637	TP53	Q00535	CDK5	T150	P152Q	152	Missense	proximal	2	no	16.442	16.384	EPSD	TCGA;ICGC;COSMIC	8.808	Down-regulation
CMGC_CDK_CDK5_CDK5_ST	P04637	TP53	Q00535	CDK5	T150	R156H	156	Missense	distal	6	no	16.442	16.431	EPSD	TCGA;ICGC;COSMIC	8.808	Down-regulation
CMGC_CDK_CDK5_CDK5_ST	P04637	TP53	Q00535	CDK5	T150	L145P	145	Missense	distal	-5	no	16.442	16.639	EPSD	TCGA;ICGC;COSMIC	8.808	Up-regulation
CMGC_CDK_CDK5_CDK5_ST	P04637	TP53	Q00535	CDK5	T150	Q144L	144	Missense	distal	-6	no	16.442	16.371	EPSD	TCGA;ICGC;COSMIC	8.808	Down-regulation
CMGC_CDK_CDK5_CDK5_ST	P04637	TP53	Q00535	CDK5	T150	Q144H	144	Missense	distal	-6	no	16.442	16.434	EPSD	TCGA;ICGC;COSMIC	8.808	Down-regulation
CMGC_CDK_CDK5_CDK5_ST	P04637	TP53	Q00535	CDK5	T150	G154V	154	Missense	distal	4	no	16.442	16.473	EPSD	TCGA;ICGC;COSMIC;GDSC;CCLE	8.808	Up-regulation
CMGC_CDK_CDK5_CDK5_ST	P04637	TP53	Q00535	CDK5	T150	V157L	157	Missense	distal	7	no	16.442	16.433	EPSD	TCGA;ICGC;COSMIC	8.808	Down-regulation
CMGC_CDK_CDK5_CDK5_ST	P04637	TP53	Q00535	CDK5	T150	P151R	151	Missense	proximal	1	no	16.442	7.495	EPSD	TCGA;ICGC;COSMIC	8.808	Loss
CMGC_CDK_CDK5_CDK5_ST	P04637	TP53	Q00535	CDK5	T150	Q144P	144	Missense	distal	-6	no	16.442	16.454	EPSD	TCGA;ICGC;COSMIC	8.808	Up-regulation
CMGC_CDK_CDK5_CDK5_ST	P04637	TP53	Q00535	CDK5	T150	V143E	143	Missense	distal	-7	no	16.442	16.414	EPSD	TCGA;ICGC;COSMIC	8.808	Down-regulation
CMGC_CDK_CDK5_CDK5_ST	P04637	TP53	Q00535	CDK5	T150	R156G	156	Missense	distal	6	no	16.442	16.425	EPSD	TCGA;ICGC;COSMIC	8.808	Down-regulation
CMGC_CDK_CDK5_CDK5_ST	P04637	TP53	Q00535	CDK5	T150	P151L	151	Missense	proximal	1	no	16.442	4.492	EPSD	TCGA;ICGC;COSMIC	8.808	Loss
CMGC_CDK_CDK5_CDK5_ST	P04637	TP53	Q00535	CDK5	T155	A159V	159	Missense	distal	4	no	10.259	10.302	EPSD	TCGA;ICGC;COSMIC;GDSC;CCLE	8.808	Up-regulation
CMGC_CDK_CDK5_CDK5_ST	P04637	TP53	Q00535	CDK5	T155	A161T	161	Missense	distal	6	no	10.259	10.271	EPSD	TCGA;ICGC;COSMIC;GDSC;CCLE	8.808	Up-regulation
CMGC_CDK_CDK5_CDK5_ST	P04637	TP53	Q00535	CDK5	T155	P152L	152	Missense	distal	-3	no	10.259	10.198	EPSD	TCGA;ICGC;COSMIC;GDSC;CCLE	8.808	Down-regulation
CMGC_CDK_CDK5_CDK5_ST	P04637	TP53	Q00535	CDK5	T155	D148N	148	Missense	distal	-7	no	10.259	10.277	EPSD	TCGA;ICGC;COSMIC	8.808	Up-regulation
CMGC_CDK_CDK5_CDK5_ST	P04637	TP53	Q00535	CDK5	T155	P151H	151	Missense	distal	-4	no	10.259	9.924	EPSD	TCGA;ICGC;COSMIC;GDSC;CCLE	8.808	Down-regulation
CMGC_CDK_CDK5_CDK5_ST	P04637	TP53	Q00535	CDK5	T155	A161V	161	Missense	distal	6	no	10.259	10.268	EPSD	TCGA;ICGC;COSMIC	8.808	Up-regulation
CMGC_CDK_CDK5_CDK5_ST	P04637	TP53	Q00535	CDK5	T155	A161S	161	Missense	distal	6	no	10.259	10.271	EPSD	TCGA;ICGC;COSMIC	8.808	Up-regulation
CMGC_CDK_CDK5_CDK5_ST	P04637	TP53	Q00535	CDK5	T155	A159P	159	Missense	distal	4	no	10.259	10.319	EPSD	TCGA;ICGC;COSMIC;CCLE	8.808	Up-regulation
CMGC_CDK_CDK5_CDK5_ST	P04637	TP53	Q00535	CDK5	T155	R158H	158	Missense	distal	3	no	10.259	9.240	EPSD	TCGA;ICGC;COSMIC;GDSC;CCLE	8.808	Down-regulation
CMGC_CDK_CDK5_CDK5_ST	P04637	TP53	Q00535	CDK5	T155	P151A	151	Missense	distal	-4	no	10.259	9.704	EPSD	TCGA;ICGC;COSMIC;CCLE	8.808	Down-regulation
CMGC_CDK_CDK5_CDK5_ST	P04637	TP53	Q00535	CDK5	T155	R156P	156	Missense	proximal	1	no	10.259	19.206	EPSD	TCGA;ICGC;COSMIC;GDSC;CCLE	8.808	Up-regulation
CMGC_CDK_CDK5_CDK5_ST	P04637	TP53	Q00535	CDK5	T155	P151S	151	Missense	distal	-4	no	10.259	10.606	EPSD	TCGA;ICGC;COSMIC;GDSC;CCLE	8.808	Up-regulation
CMGC_CDK_CDK5_CDK5_ST	P04637	TP53	Q00535	CDK5	T155	R158G	158	Missense	distal	3	no	10.259	8.877	EPSD	TCGA;ICGC;COSMIC;GDSC;CCLE	8.808	Down-regulation
CMGC_CDK_CDK5_CDK5_ST	P04637	TP53	Q00535	CDK5	T155	V157F	157	Missense	proximal	2	no	10.259	10.063	EPSD	TCGA;ICGC;COSMIC;GDSC;CCLE	8.808	Down-regulation
CMGC_CDK_CDK5_CDK5_ST	P04637	TP53	Q00535	CDK5	T155	V157G	157	Missense	proximal	2	no	10.259	10.199	EPSD	TCGA;ICGC;COSMIC	8.808	Down-regulation
CMGC_CDK_CDK5_CDK5_ST	P04637	TP53	Q00535	CDK5	T155	V157D	157	Missense	proximal	2	no	10.259	10.166	EPSD	TCGA;ICGC;COSMIC	8.808	Down-regulation
CMGC_CDK_CDK5_CDK5_ST	P04637	TP53	Q00535	CDK5	T155	I162N	162	Missense	distal	7	no	10.259	10.261	EPSD	TCGA;ICGC;COSMIC;GDSC;CCLE	8.808	Up-regulation
CMGC_CDK_CDK5_CDK5_ST	P04637	TP53	Q00535	CDK5	T155	T155I	155	Missense	central	0	yes	10.259	0.000	EPSD	TCGA;ICGC;COSMIC;CCLE	8.808	Loss
CMGC_CDK_CDK5_CDK5_ST	P04637	TP53	Q00535	CDK5	T155	R158L	158	Missense	distal	3	no	10.259	7.789	EPSD	TCGA;ICGC;COSMIC;GDSC;CCLE	8.808	Loss
CMGC_CDK_CDK5_CDK5_ST	P04637	TP53	Q00535	CDK5	T155	T155N	155	Missense	central	0	yes	10.259	0.000	EPSD	TCGA;ICGC;COSMIC;GDSC;CCLE	8.808	Loss
CMGC_CDK_CDK5_CDK5_ST	P04637	TP53	Q00535	CDK5	T155	P152S	152	Missense	distal	-3	no	10.259	10.254	EPSD	TCGA;ICGC;COSMIC;CCLE	8.808	Down-regulation
CMGC_CDK_CDK5_CDK5_ST	P04637	TP53	Q00535	CDK5	T155	R156C	156	Missense	proximal	1	no	10.259	-1.467	EPSD	TCGA;ICGC;COSMIC	8.808	Loss
CMGC_CDK_CDK5_CDK5_ST	P04637	TP53	Q00535	CDK5	T155	P151T	151	Missense	distal	-4	no	10.259	10.103	EPSD	TCGA;ICGC;COSMIC	8.808	Down-regulation
CMGC_CDK_CDK5_CDK5_ST	P04637	TP53	Q00535	CDK5	T155	T155P	155	Missense	central	0	yes	10.259	0.000	EPSD	TCGA;ICGC;COSMIC;CCLE	8.808	Loss
CMGC_CDK_CDK5_CDK5_ST	P04637	TP53	Q00535	CDK5	T155	R158S	158	Missense	distal	3	no	10.259	8.841	EPSD	TCGA;ICGC;COSMIC	8.808	Down-regulation
CMGC_CDK_CDK5_CDK5_ST	P04637	TP53	Q00535	CDK5	T155	P152Q	152	Missense	distal	-3	no	10.259	10.242	EPSD	TCGA;ICGC;COSMIC	8.808	Down-regulation
CMGC_CDK_CDK5_CDK5_ST	P04637	TP53	Q00535	CDK5	T155	R156H	156	Missense	proximal	1	no	10.259	0.694	EPSD	TCGA;ICGC;COSMIC	8.808	Loss
CMGC_CDK_CDK5_CDK5_ST	P04637	TP53	Q00535	CDK5	T155	R158P	158	Missense	distal	3	no	10.259	8.861	EPSD	TCGA;ICGC;COSMIC;GDSC;CCLE	8.808	Down-regulation
CMGC_CDK_CDK5_CDK5_ST	P04637	TP53	Q00535	CDK5	T155	G154V	154	Missense	proximal	-1	no	10.259	10.262	EPSD	TCGA;ICGC;COSMIC;GDSC;CCLE	8.808	Up-regulation
CMGC_CDK_CDK5_CDK5_ST	P04637	TP53	Q00535	CDK5	T155	V157L	157	Missense	proximal	2	no	10.259	10.125	EPSD	TCGA;ICGC;COSMIC	8.808	Down-regulation
CMGC_CDK_CDK5_CDK5_ST	P04637	TP53	Q00535	CDK5	T155	A161D	161	Missense	distal	6	no	10.259	10.260	EPSD	TCGA;ICGC;COSMIC;GDSC;CCLE	8.808	Up-regulation
CMGC_CDK_CDK5_CDK5_ST	P04637	TP53	Q00535	CDK5	T155	P151R	151	Missense	distal	-4	no	10.259	10.144	EPSD	TCGA;ICGC;COSMIC	8.808	Down-regulation
CMGC_CDK_CDK5_CDK5_ST	P04637	TP53	Q00535	CDK5	T155	M160I	160	Missense	distal	5	no	10.259	10.373	EPSD	TCGA;ICGC;COSMIC	8.808	Up-regulation
CMGC_CDK_CDK5_CDK5_ST	P04637	TP53	Q00535	CDK5	T155	R156G	156	Missense	proximal	1	no	10.259	-2.210	EPSD	TCGA;ICGC;COSMIC	8.808	Loss
CMGC_CDK_CDK5_CDK5_ST	P04637	TP53	Q00535	CDK5	T155	A161P	161	Missense	distal	6	no	10.259	10.270	EPSD	TCGA;ICGC;COSMIC	8.808	Up-regulation
CMGC_CDK_CDK5_CDK5_ST	P04637	TP53	Q00535	CDK5	T155	P151L	151	Missense	distal	-4	no	10.259	9.786	EPSD	TCGA;ICGC;COSMIC	8.808	Down-regulation
CMGC_CDK_CDK5_CDK5_ST	P04637	TP53	Q00535	CDK5	T155	I162F	162	Missense	distal	7	no	10.259	10.248	EPSD	TCGA;ICGC;COSMIC	8.808	Down-regulation
CMGC_CDK_CDK5_CDK5_ST	P04637	TP53	Q00535	CDK5	T155	R158C	158	Missense	distal	3	no	10.259	7.963	EPSD	TCGA;ICGC;COSMIC	8.808	Loss
CMGC_CDK_CDK5_CDK5_ST	P04637	TP53	Q00535	CDK5	S315	K319N	319	Missense	distal	4	no	18.385	18.290	EPSD	TCGA;ICGC;COSMIC	8.808	Down-regulation
CMGC_CDK_CDK5_CDK5_ST	P04637	TP53	Q00535	CDK5	S315	K320E	320	Missense	distal	5	no	18.385	18.134	EPSD	TCGA;ICGC;COSMIC	8.808	Down-regulation
CMGC_CDK_CDK5_CDK5_ST	P04637	TP53	Q00535	CDK5	S315	S315C	315	Missense	central	0	yes	18.385	0.000	EPSD	TCGA;ICGC;COSMIC	8.808	Loss
CMGC_CDK_CDK5_CDK5_ST	P04637	TP53	Q00535	CDK5	S362	A355T	355	Missense	distal	-7	no	9.264	9.304	EPSD	TCGA;ICGC;COSMIC	8.808	Up-regulation
CMGC_CDK_CDK5_CDK5_ST	P04637	TP53	Q00535	CDK5	S376	S376C	376	Missense	central	0	yes	10.348	0.000	EPSD	TCGA;ICGC;COSMIC	8.808	Loss
CMGC_CDK_CDK5_CDK5_ST	P04637	TP53	Q00535	CDK5	S376	Q375K	375	Missense	proximal	-1	no	10.348	10.352	EPSD	TCGA;ICGC;COSMIC	8.808	Up-regulation
CMGC_CDK_CDK5_CDK5_ST	P04637	TP53	Q00535	CDK5	S378	S376C	376	Missense	proximal	-2	no	11.670	11.198	EPSD	TCGA;ICGC;COSMIC	8.808	Down-regulation
CMGC_CDK_CDK5_CDK5_ST	P04637	TP53	Q00535	CDK5	S378	Q375K	375	Missense	distal	-3	no	11.670	11.716	EPSD	TCGA;ICGC;COSMIC	8.808	Up-regulation
CMGC_CDK_CDK5_CDK5_ST	Q99490	AGAP2	Q00535	CDK5	S224	K225N	225	Missense	proximal	1	no	0.510	9.450	EPSD	TCGA;ICGC;COSMIC	8.808	Gain
CMGC_CDK_CDK5_CDK5_ST	Q99490	AGAP2	Q00535	CDK5	S267	R263Q	263	Missense	distal	-4	no	20.291	20.281	EPSD	TCGA;ICGC;COSMIC	8.808	Down-regulation
CMGC_CDK_CDK5_CDK5_ST	Q99490	AGAP2	Q00535	CDK5	S267	G264E	264	Missense	distal	-3	no	20.291	20.294	EPSD	TCGA;ICGC;COSMIC	8.808	Up-regulation
CMGC_CDK_CDK5_CDK5_ST	Q99490	AGAP2	Q00535	CDK5	S267	K270R	270	Missense	distal	3	no	20.291	19.972	EPSD	TCGA;ICGC;COSMIC	8.808	Down-regulation
CMGC_CDK_CDK5_CDK5_ST	Q99490	AGAP2	Q00535	CDK5	S523	A521T	521	Missense	proximal	-2	no	18.242	18.480	EPSD	TCGA	8.808	Up-regulation
CMGC_CDK_CDK5_CDK5_ST	Q99490	AGAP2	Q00535	CDK5	S523	A530T	530	Missense	distal	7	no	18.242	18.251	EPSD	TCGA;COSMIC	8.808	Up-regulation
CMGC_CDK_CDK5_CDK5_ST	Q99490	AGAP2	Q00535	CDK5	S523	G528E	528	Missense	distal	5	no	18.242	18.233	EPSD	TCGA;COSMIC	8.808	Down-regulation
CMGC_CDK_CDK5_CDK5_ST	Q99490	AGAP2	Q00535	CDK5	S585	P583L	583	Missense	proximal	-2	no	18.493	18.078	EPSD	TCGA;COSMIC	8.808	Down-regulation
CMGC_CDK_CDK5_CDK5_ST	Q99490	AGAP2	Q00535	CDK5	T593	P594L	594	Missense	proximal	1	no	17.193	5.243	EPSD	TCGA;COSMIC	8.808	Loss
CMGC_CDK_CDK5_CDK5_ST	Q99490	AGAP2	Q00535	CDK5	S615	P613L	613	Missense	proximal	-2	no	18.478	18.063	EPSD	TCGA;COSMIC	8.808	Down-regulation
CMGC_CDK_CDK5_CDK5_ST	Q99490	AGAP2	Q00535	CDK5	S615	R621W	621	Missense	distal	6	no	18.478	18.461	EPSD	TCGA	8.808	Down-regulation
CMGC_CDK_CDK5_CDK5_ST	Q99490	AGAP2	Q00535	CDK5	T635	A642E	642	Missense	distal	7	no	16.338	16.339	EPSD	TCGA;COSMIC	8.808	Up-regulation
CMGC_CDK_CDK5_CDK5_ST	Q99490	AGAP2	Q00535	CDK5	S656	E659K	659	Missense	distal	3	no	7.219	9.505	EPSD	TCGA;COSMIC	8.808	Gain
CMGC_CDK_CDK5_CDK5_ST	Q99490	AGAP2	Q00535	CDK5	T812	R805Q	805	Missense	distal	-7	no	16.822	16.802	EPSD	TCGA;COSMIC	8.808	Down-regulation
CMGC_CDK_CDK5_CDK5_ST	Q99490	AGAP2	Q00535	CDK5	S827	P824S	824	Missense	distal	-3	no	18.771	18.766	EPSD	TCGA;ICGC;COSMIC	8.808	Down-regulation
CMGC_CDK_CDK5_CDK5_ST	O15516	CLOCK	Q00535	CDK5	S427	S431A	431	Missense	distal	4	no	17.450	17.388	EPSD	TCGA;ICGC;COSMIC	8.808	Down-regulation
CMGC_CDK_CDK5_CDK5_ST	O15516	CLOCK	Q00535	CDK5	T429	S431A	431	Missense	proximal	2	no	16.361	16.267	EPSD	TCGA;ICGC;COSMIC	8.808	Down-regulation
CMGC_CDK_CDK5_CDK5_ST	O15516	CLOCK	Q00535	CDK5	S437	S431A	431	Missense	distal	-6	no	9.628	9.513	EPSD	TCGA;ICGC;COSMIC	8.808	Down-regulation
CMGC_CDK_CDK5_CDK5_ST	O15516	CLOCK	Q00535	CDK5	S437	H442Y	442	Missense	distal	5	no	9.628	9.491	EPSD	TCGA;ICGC;COSMIC	8.808	Down-regulation
CMGC_CDK_CDK5_CDK5_ST	O15516	CLOCK	Q00535	CDK5	T461	T459M	459	Missense	proximal	-2	no	18.112	17.679	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	8.808	Down-regulation
CMGC_CDK_CDK5_CDK5_ST	Q14194	CRMP1	Q00535	CDK5	T509	P510S	510	Missense	proximal	1	no	15.893	3.992	PhosphoSitePlus;EPSD	TCGA	8.808	Loss
CMGC_CDK_CDK5_CDK5_ST	Q14194	CRMP1	Q00535	CDK5	T514	P510S	510	Missense	distal	-4	no	16.996	17.342	EPSD	TCGA	8.808	Up-regulation
CMGC_CDK_CDK5_CDK5_ST	P35612	ADD2	Q00535	CDK5	S11	T5A	5	Missense	distal	-6	no	19.042	18.956	EPSD	TCGA;ICGC;COSMIC;GDSC;CCLE	8.808	Down-regulation
CMGC_CDK_CDK5_CDK5_ST	P35612	ADD2	Q00535	CDK5	S11	P15S	15	Missense	distal	4	no	19.042	19.044	EPSD	TCGA;ICGC;COSMIC	8.808	Up-regulation
CMGC_CDK_CDK5_CDK5_ST	P35612	ADD2	Q00535	CDK5	S60	E65K	65	Missense	distal	5	no	15.928	16.179	EPSD	TCGA;ICGC;COSMIC	8.808	Up-regulation
CMGC_CDK_CDK5_CDK5_ST	P35612	ADD2	Q00535	CDK5	S60	M56I	56	Missense	distal	-4	no	15.928	16.383	EPSD	TCGA;ICGC;COSMIC	8.808	Up-regulation
CMGC_CDK_CDK5_CDK5_ST	P35612	ADD2	Q00535	CDK5	T436	W433C	433	Missense	distal	-3	no	17.896	17.871	EPSD	TCGA;ICGC;COSMIC	8.808	Down-regulation
CMGC_CDK_CDK5_CDK5_ST	P35612	ADD2	Q00535	CDK5	T436	T436M	436	Missense	central	0	yes	17.896	0.000	EPSD	TCGA;ICGC;COSMIC	8.808	Loss
CMGC_CDK_CDK5_CDK5_ST	P35612	ADD2	Q00535	CDK5	T436	T436A	436	Missense	central	0	yes	17.896	0.000	EPSD	TCGA;ICGC;COSMIC	8.808	Loss
CMGC_CDK_CDK5_CDK5_ST	P35612	ADD2	Q00535	CDK5	T436	R442W	442	Missense	distal	6	no	17.896	17.879	EPSD	TCGA;ICGC;COSMIC;GDSC;CCLE	8.808	Down-regulation
CMGC_CDK_CDK5_CDK5_ST	P35612	ADD2	Q00535	CDK5	T436	R432H	432	Missense	distal	-4	no	17.896	17.676	EPSD	TCGA;ICGC;COSMIC	8.808	Down-regulation
CMGC_CDK_CDK5_CDK5_ST	P35612	ADD2	Q00535	CDK5	S512	A513P	513	Missense	proximal	1	no	7.483	18.510	EPSD	TCGA;ICGC;COSMIC	8.808	Gain
CMGC_CDK_CDK5_CDK5_ST	P35612	ADD2	Q00535	CDK5	S530	V523I	523	Missense	distal	-7	no	17.904	17.888	EPSD	TCGA;ICGC;COSMIC;GDSC;CCLE	8.808	Down-regulation
CMGC_CDK_CDK5_CDK5_ST	P35612	ADD2	Q00535	CDK5	S530	S530N	530	Missense	central	0	yes	17.904	0.000	EPSD	TCGA;ICGC;COSMIC	8.808	Loss
CMGC_CDK_CDK5_CDK5_ST	P35612	ADD2	Q00535	CDK5	S530	I524V	524	Missense	distal	-6	no	17.904	17.932	EPSD	TCGA;ICGC;COSMIC	8.808	Up-regulation
CMGC_CDK_CDK5_CDK5_ST	P35612	ADD2	Q00535	CDK5	S592	A599V	599	Missense	distal	7	no	19.175	19.183	EPSD	TCGA;ICGC;COSMIC	8.808	Up-regulation
CMGC_CDK_CDK5_CDK5_ST	P35612	ADD2	Q00535	CDK5	S592	S596Y	596	Missense	distal	4	no	19.175	19.090	EPSD	TCGA;ICGC	8.808	Down-regulation
CMGC_CDK_CDK5_CDK5_ST	P35612	ADD2	Q00535	CDK5	S592	S596P	596	Missense	distal	4	no	19.175	19.174	EPSD	TCGA;ICGC	8.808	Down-regulation
CMGC_CDK_CDK5_CDK5_ST	P35612	ADD2	Q00535	CDK5	S600	A599V	599	Missense	proximal	-1	no	17.846	17.850	EPSD	TCGA;ICGC;COSMIC	8.808	Up-regulation
CMGC_CDK_CDK5_CDK5_ST	P35612	ADD2	Q00535	CDK5	S600	S596Y	596	Missense	distal	-4	no	17.846	16.866	EPSD	TCGA;ICGC	8.808	Down-regulation
CMGC_CDK_CDK5_CDK5_ST	P35612	ADD2	Q00535	CDK5	S600	S600F	600	Missense	central	0	yes	17.846	0.000	EPSD	TCGA;ICGC;COSMIC	8.808	Loss
CMGC_CDK_CDK5_CDK5_ST	P35612	ADD2	Q00535	CDK5	S600	S596P	596	Missense	distal	-4	no	17.846	17.500	EPSD	TCGA;ICGC	8.808	Down-regulation
CMGC_CDK_CDK5_CDK5_ST	P35612	ADD2	Q00535	CDK5	S604	E610K	610	Missense	distal	6	no	19.529	19.547	EPSD;PhosphoSitePlus	TCGA;COSMIC	8.808	Up-regulation
CMGC_CDK_CDK5_CDK5_ST	P35612	ADD2	Q00535	CDK5	S604	A599V	599	Missense	distal	-5	no	19.529	19.654	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	8.808	Up-regulation
CMGC_CDK_CDK5_CDK5_ST	P35612	ADD2	Q00535	CDK5	S604	S600F	600	Missense	distal	-4	no	19.529	18.368	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	8.808	Down-regulation
CMGC_CDK_CDK5_CDK5_ST	P35612	ADD2	Q00535	CDK5	S613	E610K	610	Missense	distal	-3	no	17.339	17.412	EPSD	TCGA;COSMIC	8.808	Up-regulation
CMGC_CDK_CDK5_CDK5_ST	P35612	ADD2	Q00535	CDK5	S617	S621F	621	Missense	distal	4	no	19.900	19.788	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	8.808	Down-regulation
CMGC_CDK_CDK5_CDK5_ST	P35612	ADD2	Q00535	CDK5	S617	E610K	610	Missense	distal	-7	no	19.900	19.963	EPSD;PhosphoSitePlus	TCGA;COSMIC	8.808	Up-regulation
CMGC_CDK_CDK5_CDK5_ST	P35612	ADD2	Q00535	CDK5	S667	E660K	660	Missense	distal	-7	no	9.069	9.132	EPSD	TCGA;ICGC;COSMIC	8.808	Up-regulation
CMGC_CDK_CDK5_CDK5_ST	P35612	ADD2	Q00535	CDK5	S693	S686L	686	Missense	distal	-7	no	18.849	18.793	EPSD	TCGA;ICGC;COSMIC	8.808	Down-regulation
CMGC_CDK_CDK5_CDK5_ST	P35612	ADD2	Q00535	CDK5	S693	G690S	690	Missense	distal	-3	no	18.849	18.890	EPSD	TCGA;ICGC;COSMIC	8.808	Up-regulation
CMGC_CDK_CDK5_CDK5_ST	P35612	ADD2	Q00535	CDK5	S697	G690S	690	Missense	distal	-7	no	19.283	19.335	EPSD	TCGA;ICGC;COSMIC	8.808	Up-regulation
CMGC_CDK_CDK5_CDK5_ST	P35612	ADD2	Q00535	CDK5	S701	K707N	707	Missense	distal	6	no	19.958	19.944	PhosphoSitePlus;EPSD	TCGA;ICGC;COSMIC	8.808	Down-regulation
CMGC_CDK_CDK5_CDK5_ST	P35612	ADD2	Q00535	CDK5	T711	K707N	707	Missense	distal	-4	no	17.101	16.714	EPSD	TCGA;ICGC;COSMIC	8.808	Down-regulation
CMGC_CDK_CDK5_CDK5_ST	P35612	ADD2	Q00535	CDK5	T711	P712L	712	Missense	proximal	1	no	17.101	5.152	EPSD	TCGA;ICGC;COSMIC	8.808	Loss
CMGC_CDK_CDK5_CDK5_ST	O00429	DNM1L	Q00535	CDK5	S529	S533F	533	Missense	distal	4	no	11.576	11.464	EPSD	TCGA;ICGC;COSMIC	8.808	Down-regulation
CMGC_CDK_CDK5_CDK5_ST	O00429	DNM1L	Q00535	CDK5	S529	S534C	534	Missense	distal	5	no	11.576	11.382	EPSD	TCGA;ICGC;COSMIC	8.808	Down-regulation
CMGC_CDK_CDK5_CDK5_ST	O00429	DNM1L	Q00535	CDK5	S529	R522K	522	Missense	distal	-7	no	11.576	11.593	EPSD	TCGA;COSMIC	8.808	Up-regulation
CMGC_CDK_CDK5_CDK5_ST	O00429	DNM1L	Q00535	CDK5	S616	A622V	622	Missense	distal	6	no	19.887	19.896	PhosphoSitePlus	TCGA;COSMIC	8.808	Up-regulation
CMGC_CDK_CDK5_CDK5_ST	O00429	DNM1L	Q00535	CDK5	S616	G620C	620	Missense	distal	4	no	19.887	19.847	PhosphoSitePlus	TCGA	8.808	Down-regulation
CMGC_CDK_CDK5_CDK5_ST	Q8IV63	VRK3	Q00535	CDK5	S59	P60A	60	Missense	proximal	1	no	20.284	9.257	EPSD	TCGA;ICGC;COSMIC	8.808	Down-regulation
CMGC_CDK_CDK5_CDK5_ST	Q8IV63	VRK3	Q00535	CDK5	S100	S95F	95	Missense	distal	-5	no	9.393	9.064	EPSD	TCGA;ICGC;COSMIC	8.808	Down-regulation
CMGC_CDK_CDK5_CDK5_ST	Q8IV63	VRK3	Q00535	CDK5	S108	Q110H	110	Missense	proximal	2	no	19.517	19.541	PhosphoSitePlus	TCGA;COSMIC	8.808	Up-regulation
CMGC_CDK_CDK5_CDK5_ST	Q8IV63	VRK3	Q00535	CDK5	S115	Q110H	110	Missense	distal	-5	no	17.858	17.846	EPSD	TCGA;COSMIC	8.808	Down-regulation
CMGC_CDK_CDK5_CDK5_ST	Q8IV63	VRK3	Q00535	CDK5	S115	S122G	122	Missense	distal	7	no	17.858	17.848	EPSD	TCGA;COSMIC	8.808	Down-regulation
CMGC_CDK_CDK5_CDK5_ST	Q8IV63	VRK3	Q00535	CDK5	S122	S122G	122	Missense	central	0	yes	19.149	0.000	EPSD	TCGA;COSMIC	8.808	Loss
CMGC_CDK_CDK5_CDK5_ST	Q8IV63	VRK3	Q00535	CDK5	S129	S122G	122	Missense	distal	-7	no	19.829	19.777	EPSD	TCGA;COSMIC	8.808	Down-regulation
CMGC_CDK_CDK5_CDK5_ST	Q8IV63	VRK3	Q00535	CDK5	S143	R144L	144	Missense	proximal	1	no	9.357	6.355	EPSD	TCGA;COSMIC	8.808	Loss
CMGC_CDK_CDK5_CDK5_ST	Q8IV63	VRK3	Q00535	CDK5	S273	A269S	269	Missense	distal	-4	no	18.924	19.826	EPSD	TCGA;COSMIC	8.808	Up-regulation
CMGC_CDK_CDK5_CDK5_ST	Q8IV63	VRK3	Q00535	CDK5	S273	S273N	273	Missense	central	0	yes	18.924	0.000	EPSD	TCGA;COSMIC	8.808	Loss
CMGC_CDK_CDK5_CDK5_ST	Q8IV63	VRK3	Q00535	CDK5	S273	P274S	274	Missense	proximal	1	no	18.924	7.023	EPSD	TCGA;COSMIC	8.808	Loss
CMGC_CDK_CDK5_CDK5_ST	Q8IV63	VRK3	Q00535	CDK5	S348	E351K	351	Missense	distal	3	no	17.815	20.102	EPSD	TCGA;COSMIC	8.808	Up-regulation
CMGC_CDK_CDK5_CDK5_ST	Q8IV63	VRK3	Q00535	CDK5	S348	P349S	349	Missense	proximal	1	no	17.815	5.914	EPSD	TCGA;COSMIC	8.808	Loss
CMGC_CDK_CDK5_CDK5_ST	Q8IV63	VRK3	Q00535	CDK5	S348	Y342H	342	Missense	distal	-6	no	17.815	17.890	EPSD	TCGA;COSMIC	8.808	Up-regulation
CMGC_CDK_CDK5_CDK5_ST	Q15717	ELAVL1	Q00535	CDK5	S146	T143A	143	Missense	distal	-3	no	8.850	8.805	EPSD	TCGA;ICGC;COSMIC;GDSC;CCLE	8.808	Loss
CMGC_CDK_CDK5_CDK5_ST	Q15717	ELAVL1	Q00535	CDK5	S146	R153W	153	Missense	distal	7	no	8.850	8.839	EPSD	TCGA;ICGC;COSMIC	8.808	Down-regulation
CMGC_CDK_CDK5_CDK5_ST	Q15717	ELAVL1	Q00535	CDK5	S221	R217T	217	Missense	distal	-4	no	17.779	17.738	EPSD	TCGA;ICGC;COSMIC	8.808	Down-regulation
CMGC_CDK_CDK5_CDK5_ST	Q15717	ELAVL1	Q00535	CDK5	S221	D226N	226	Missense	distal	5	no	17.779	17.848	EPSD	TCGA;ICGC;COSMIC	8.808	Up-regulation
CMGC_CDK_CDK5_CDK5_ST	Q02750	MAP2K1	Q00535	CDK5	T55	Q56P	56	Missense	proximal	1	no	8.124	17.100	EPSD	TCGA;ICGC;COSMIC;GDSC;CCLE	8.808	Gain
CMGC_CDK_CDK5_CDK5_ST	Q02750	MAP2K1	Q00535	CDK5	S200	E203K	203	Missense	distal	3	no	8.128	10.415	EPSD	TCGA;ICGC;COSMIC;GDSC	8.808	Gain
CMGC_CDK_CDK5_CDK5_ST	Q02750	MAP2K1	Q00535	CDK5	S231	L235H	235	Missense	distal	4	no	19.243	19.303	EPSD	TCGA;ICGC;COSMIC	8.808	Up-regulation
CMGC_CDK_CDK5_CDK5_ST	Q02750	MAP2K1	Q00535	CDK5	S231	S231L	231	Missense	central	0	yes	19.243	0.000	EPSD	TCGA;ICGC;COSMIC	8.808	Loss
CMGC_CDK_CDK5_CDK5_ST	Q02750	MAP2K1	Q00535	CDK5	S231	V224M	224	Missense	distal	-7	no	19.243	19.189	EPSD	TCGA;ICGC;COSMIC	8.808	Down-regulation
CMGC_CDK_CDK5_CDK5_ST	Q02750	MAP2K1	Q00535	CDK5	S231	R227K	227	Missense	distal	-4	no	19.243	19.579	EPSD	TCGA;ICGC;COSMIC	8.808	Up-regulation
CMGC_CDK_CDK5_CDK5_ST	Q02750	MAP2K1	Q00535	CDK5	T286	P290S	290	Missense	distal	4	no	18.401	18.403	EPSD	TCGA;ICGC	8.808	Up-regulation
CMGC_CDK_CDK5_CDK5_ST	Q02750	MAP2K1	Q00535	CDK5	T292	G294R	294	Missense	proximal	2	no	19.368	19.541	PhosphoSitePlus	TCGA;ICGC;COSMIC	8.808	Up-regulation
CMGC_CDK_CDK5_CDK5_ST	Q02750	MAP2K1	Q00535	CDK5	T292	G294V	294	Missense	proximal	2	no	19.368	19.429	PhosphoSitePlus	TCGA;ICGC;COSMIC	8.808	Up-regulation
CMGC_CDK_CDK5_CDK5_ST	Q02750	MAP2K1	Q00535	CDK5	T292	G294E	294	Missense	proximal	2	no	19.368	19.340	PhosphoSitePlus	TCGA;ICGC;COSMIC	8.808	Down-regulation
CMGC_CDK_CDK5_CDK5_ST	Q02750	MAP2K1	Q00535	CDK5	T292	P290S	290	Missense	proximal	-2	no	19.368	19.270	PhosphoSitePlus	TCGA;ICGC	8.808	Down-regulation
CMGC_CDK_CDK5_CDK5_ST	Q14814	MEF2D	Q00535	CDK5	S78	N73S	73	Missense	distal	-5	no	8.836	8.927	EPSD	TCGA;ICGC;COSMIC	8.808	Up-regulation
CMGC_CDK_CDK5_CDK5_ST	Q14814	MEF2D	Q00535	CDK5	S78	R79H	79	Missense	proximal	1	no	8.836	-0.729	EPSD	TCGA;ICGC;COSMIC	8.808	Loss
CMGC_CDK_CDK5_CDK5_ST	Q14814	MEF2D	Q00535	CDK5	S78	D83G	83	Missense	distal	5	no	8.836	8.865	EPSD	TCGA;ICGC;COSMIC	8.808	Up-regulation
CMGC_CDK_CDK5_CDK5_ST	Q14814	MEF2D	Q00535	CDK5	S98	G95V	95	Missense	distal	-3	no	16.728	16.760	EPSD	TCGA;ICGC;COSMIC	8.808	Up-regulation
CMGC_CDK_CDK5_CDK5_ST	Q14814	MEF2D	Q00535	CDK5	S98	C96Y	96	Missense	proximal	-2	no	16.728	16.771	EPSD	TCGA;ICGC;COSMIC	8.808	Up-regulation
CMGC_CDK_CDK5_CDK5_ST	Q14814	MEF2D	Q00535	CDK5	S98	E100K	100	Missense	proximal	2	no	16.728	16.978	EPSD	TCGA;ICGC	8.808	Up-regulation
CMGC_CDK_CDK5_CDK5_ST	Q14814	MEF2D	Q00535	CDK5	S98	G92D	92	Missense	distal	-6	no	16.728	16.725	EPSD	TCGA;ICGC;COSMIC	8.808	Down-regulation
CMGC_CDK_CDK5_CDK5_ST	Q14814	MEF2D	Q00535	CDK5	S110	P111R	111	Missense	proximal	1	no	16.893	7.946	EPSD	TCGA;ICGC;COSMIC	8.808	Loss
CMGC_CDK_CDK5_CDK5_ST	Q14814	MEF2D	Q00535	CDK5	S110	P111S	111	Missense	proximal	1	no	16.893	4.992	EPSD	TCGA;ICGC;COSMIC	8.808	Loss
CMGC_CDK_CDK5_CDK5_ST	Q14814	MEF2D	Q00535	CDK5	S180	L179M	179	Missense	proximal	-1	no	17.294	17.293	EPSD	TCGA;COSMIC	8.808	Down-regulation
CMGC_CDK_CDK5_CDK5_ST	Q14814	MEF2D	Q00535	CDK5	S192	G194V	194	Missense	proximal	2	no	17.011	17.072	EPSD	TCGA;COSMIC	8.808	Up-regulation
CMGC_CDK_CDK5_CDK5_ST	Q14814	MEF2D	Q00535	CDK5	S219	C217Y	217	Missense	proximal	-2	no	16.603	16.646	EPSD	TCGA	8.808	Up-regulation
CMGC_CDK_CDK5_CDK5_ST	Q14814	MEF2D	Q00535	CDK5	S219	N223D	223	Missense	distal	4	no	16.603	16.573	EPSD	TCGA	8.808	Down-regulation
CMGC_CDK_CDK5_CDK5_ST	Q14814	MEF2D	Q00535	CDK5	S231	S227G	227	Missense	distal	-4	no	17.677	16.835	EPSD	TCGA;COSMIC	8.808	Down-regulation
CMGC_CDK_CDK5_CDK5_ST	Q14814	MEF2D	Q00535	CDK5	S231	R229Q	229	Missense	proximal	-2	no	17.677	17.540	EPSD	TCGA;COSMIC	8.808	Down-regulation
CMGC_CDK_CDK5_CDK5_ST	Q14814	MEF2D	Q00535	CDK5	S251	P252A	252	Missense	proximal	1	no	17.827	6.801	EPSD	TCGA;COSMIC	8.808	Loss
CMGC_CDK_CDK5_CDK5_ST	Q14814	MEF2D	Q00535	CDK5	S251	P255S	255	Missense	distal	4	no	17.827	17.829	EPSD	TCGA;COSMIC	8.808	Up-regulation
CMGC_CDK_CDK5_CDK5_ST	Q14814	MEF2D	Q00535	CDK5	S251	P252L	252	Missense	proximal	1	no	17.827	5.877	EPSD	TCGA;COSMIC	8.808	Loss
CMGC_CDK_CDK5_CDK5_ST	Q14814	MEF2D	Q00535	CDK5	T259	P255S	255	Missense	distal	-4	no	8.663	9.010	EPSD	TCGA;COSMIC	8.808	Gain
CMGC_CDK_CDK5_CDK5_ST	Q14814	MEF2D	Q00535	CDK5	S444	S437N	437	Missense	distal	-7	no	20.530	20.505	PhosphoSitePlus	TCGA;COSMIC	8.808	Down-regulation
CMGC_CDK_CDK5_CDK5_ST	Q14814	MEF2D	Q00535	CDK5	S444	P445S	445	Missense	proximal	1	no	20.530	8.629	PhosphoSitePlus	TCGA;COSMIC	8.808	Loss
CMGC_CDK_CDK5_CDK5_ST	Q14814	MEF2D	Q00535	CDK5	S446	P445S	445	Missense	proximal	-1	no	10.776	10.777	EPSD	TCGA;COSMIC	8.808	Up-regulation
CMGC_CDK_CDK5_CDK5_ST	Q14814	MEF2D	Q00535	CDK5	S450	P445S	445	Missense	distal	-5	no	18.610	18.632	EPSD	TCGA;COSMIC	8.808	Up-regulation
CMGC_CDK_CDK5_CDK5_ST	Q14814	MEF2D	Q00535	CDK5	S450	P456S	456	Missense	distal	6	no	18.610	18.611	EPSD	TCGA;COSMIC	8.808	Up-regulation
CMGC_CDK_CDK5_CDK5_ST	Q14814	MEF2D	Q00535	CDK5	S450	P455S	455	Missense	distal	5	no	18.610	18.622	EPSD	TCGA;COSMIC	8.808	Up-regulation
CMGC_CDK_CDK5_CDK5_ST	Q14814	MEF2D	Q00535	CDK5	S450	P455A	455	Missense	distal	5	no	18.610	18.488	EPSD	TCGA;COSMIC	8.808	Down-regulation
CMGC_CDK_CDK5_CDK5_ST	Q14814	MEF2D	Q00535	CDK5	S472	P473L	473	Missense	proximal	1	no	16.962	5.012	EPSD	TCGA;COSMIC	8.808	Loss
CMGC_CDK_CDK5_CDK5_ST	Q14814	MEF2D	Q00535	CDK5	S472	A474V	474	Missense	proximal	2	no	16.962	17.043	EPSD	TCGA;COSMIC	8.808	Up-regulation
CMGC_CDK_CDK5_CDK5_ST	Q14814	MEF2D	Q00535	CDK5	S472	Y478H	478	Missense	distal	6	no	16.962	16.973	EPSD	TCGA;COSMIC	8.808	Up-regulation
CMGC_CDK_CDK5_CDK5_ST	Q14814	MEF2D	Q00535	CDK5	S472	D468N	468	Missense	distal	-4	no	16.962	17.126	EPSD	TCGA;COSMIC	8.808	Up-regulation
CMGC_CDK_CDK5_CDK5_ST	Q14814	MEF2D	Q00535	CDK5	S472	G476E	476	Missense	distal	4	no	16.962	16.960	EPSD	TCGA;COSMIC	8.808	Down-regulation
CMGC_CDK_CDK5_CDK5_ST	Q14814	MEF2D	Q00535	CDK5	S508	E506K	506	Missense	proximal	-2	no	9.177	9.590	EPSD	TCGA;COSMIC	8.808	Up-regulation
CMGC_CDK_CDK5_CDK5_ST	Q14814	MEF2D	Q00535	CDK5	S508	R514W	514	Missense	distal	6	no	9.177	9.160	EPSD	TCGA;COSMIC;GDSC;CCLE	8.808	Down-regulation
CMGC_CDK_CDK5_CDK5_ST	Q14814	MEF2D	Q00535	CDK5	S508	R514Q	514	Missense	distal	6	no	9.177	9.166	EPSD	TCGA;COSMIC;GDSC;CCLE	8.808	Down-regulation
CMGC_CDK_CDK5_CDK5_ST	Q96KR7	PHACTR3	Q00535	CDK5	T45	E41K	41	Missense	distal	-4	no	15.997	16.500	EPSD	TCGA;COSMIC	8.808	Up-regulation
CMGC_CDK_CDK5_CDK5_ST	Q96KR7	PHACTR3	Q00535	CDK5	T45	R49C	49	Missense	distal	4	no	15.997	15.889	EPSD	TCGA;COSMIC;GDSC;CCLE	8.808	Down-regulation
CMGC_CDK_CDK5_CDK5_ST	Q96KR7	PHACTR3	Q00535	CDK5	T45	R49H	49	Missense	distal	4	no	15.997	15.957	EPSD	TCGA;COSMIC	8.808	Down-regulation
CMGC_CDK_CDK5_CDK5_ST	Q96KR7	PHACTR3	Q00535	CDK5	T45	A48E	48	Missense	distal	3	no	15.997	15.673	EPSD	TCGA;COSMIC	8.808	Down-regulation
CMGC_CDK_CDK5_CDK5_ST	Q96KR7	PHACTR3	Q00535	CDK5	S156	T160I	160	Missense	distal	4	no	17.190	17.149	EPSD	TCGA;COSMIC	8.808	Down-regulation
CMGC_CDK_CDK5_CDK5_ST	Q96KR7	PHACTR3	Q00535	CDK5	S156	Q153H	153	Missense	distal	-3	no	17.190	17.185	EPSD	TCGA	8.808	Down-regulation
CMGC_CDK_CDK5_CDK5_ST	Q96KR7	PHACTR3	Q00535	CDK5	S156	T162M	162	Missense	distal	6	no	17.190	17.173	EPSD	TCGA;COSMIC;GDSC;CCLE	8.808	Down-regulation
CMGC_CDK_CDK5_CDK5_ST	Q96KR7	PHACTR3	Q00535	CDK5	S156	A159T	159	Missense	distal	3	no	17.190	17.971	EPSD	TCGA;COSMIC	8.808	Up-regulation
CMGC_CDK_CDK5_CDK5_ST	Q96KR7	PHACTR3	Q00535	CDK5	S156	D163G	163	Missense	distal	7	no	17.190	17.189	EPSD	TCGA;COSMIC	8.808	Down-regulation
CMGC_CDK_CDK5_CDK5_ST	Q96KR7	PHACTR3	Q00535	CDK5	S156	G155R	155	Missense	proximal	-1	no	17.190	17.194	EPSD	TCGA;COSMIC	8.808	Up-regulation
CMGC_CDK_CDK5_CDK5_ST	Q96KR7	PHACTR3	Q00535	CDK5	S156	G155E	155	Missense	proximal	-1	no	17.190	17.191	EPSD	TCGA;COSMIC	8.808	Up-regulation
CMGC_CDK_CDK5_CDK5_ST	Q96KR7	PHACTR3	Q00535	CDK5	S216	A209D	209	Missense	distal	-7	no	18.743	18.753	EPSD	TCGA	8.808	Up-regulation
CMGC_CDK_CDK5_CDK5_ST	Q96KR7	PHACTR3	Q00535	CDK5	S216	A211V	211	Missense	distal	-5	no	18.743	18.868	EPSD	TCGA	8.808	Up-regulation
CMGC_CDK_CDK5_CDK5_ST	Q96KR7	PHACTR3	Q00535	CDK5	S216	E222K	222	Missense	distal	6	no	18.743	18.761	EPSD	TCGA;COSMIC	8.808	Up-regulation
CMGC_CDK_CDK5_CDK5_ST	Q96KR7	PHACTR3	Q00535	CDK5	S216	S213F	213	Missense	distal	-3	no	18.743	18.666	EPSD	TCGA;COSMIC;GDSC;CCLE	8.808	Down-regulation
CMGC_CDK_CDK5_CDK5_ST	Q96KR7	PHACTR3	Q00535	CDK5	S230	Q227H	227	Missense	distal	-3	no	16.683	16.678	EPSD	TCGA;COSMIC	8.808	Down-regulation
CMGC_CDK_CDK5_CDK5_ST	Q96KR7	PHACTR3	Q00535	CDK5	S230	S224F	224	Missense	distal	-6	no	16.683	16.510	EPSD	TCGA;COSMIC	8.808	Down-regulation
CMGC_CDK_CDK5_CDK5_ST	Q96KR7	PHACTR3	Q00535	CDK5	S230	P231L	231	Missense	proximal	1	no	16.683	4.733	EPSD	TCGA;COSMIC	8.808	Loss
CMGC_CDK_CDK5_CDK5_ST	Q96KR7	PHACTR3	Q00535	CDK5	T236	P239S	239	Missense	distal	3	no	17.851	17.831	EPSD	TCGA;COSMIC	8.808	Down-regulation
CMGC_CDK_CDK5_CDK5_ST	Q96KR7	PHACTR3	Q00535	CDK5	T236	A241T	241	Missense	distal	5	no	17.851	17.985	EPSD	TCGA;COSMIC	8.808	Up-regulation
CMGC_CDK_CDK5_CDK5_ST	Q96KR7	PHACTR3	Q00535	CDK5	T236	P229T	229	Missense	distal	-7	no	17.851	17.841	EPSD	TCGA;COSMIC	8.808	Down-regulation
CMGC_CDK_CDK5_CDK5_ST	Q96KR7	PHACTR3	Q00535	CDK5	T236	P231L	231	Missense	distal	-5	no	17.851	17.654	EPSD	TCGA;COSMIC	8.808	Down-regulation
CMGC_CDK_CDK5_CDK5_ST	Q96KR7	PHACTR3	Q00535	CDK5	T274	P275L	275	Missense	proximal	1	no	16.467	4.517	EPSD	TCGA;COSMIC	8.808	Loss
CMGC_CDK_CDK5_CDK5_ST	Q96KR7	PHACTR3	Q00535	CDK5	S278	P275L	275	Missense	distal	-3	no	17.242	17.181	EPSD	TCGA;COSMIC	8.808	Down-regulation
CMGC_CDK_CDK5_CDK5_ST	Q96KR7	PHACTR3	Q00535	CDK5	S278	H285Y	285	Missense	distal	7	no	17.242	17.233	EPSD	TCGA;COSMIC	8.808	Down-regulation
CMGC_CDK_CDK5_CDK5_ST	Q96KR7	PHACTR3	Q00535	CDK5	S291	E295K	295	Missense	distal	4	no	8.927	9.044	EPSD	TCGA;COSMIC	8.808	Up-regulation
CMGC_CDK_CDK5_CDK5_ST	Q96KR7	PHACTR3	Q00535	CDK5	S291	L288I	288	Missense	distal	-3	no	8.927	8.958	EPSD	TCGA;COSMIC	8.808	Up-regulation
CMGC_CDK_CDK5_CDK5_ST	Q96KR7	PHACTR3	Q00535	CDK5	S291	P287H	287	Missense	distal	-4	no	8.927	8.592	EPSD	TCGA;COSMIC	8.808	Loss
CMGC_CDK_CDK5_CDK5_ST	Q96KR7	PHACTR3	Q00535	CDK5	S291	P289T	289	Missense	proximal	-2	no	8.927	8.787	EPSD	TCGA;COSMIC	8.808	Loss
CMGC_CDK_CDK5_CDK5_ST	Q96KR7	PHACTR3	Q00535	CDK5	S291	H285Y	285	Missense	distal	-6	no	8.927	8.852	EPSD	TCGA;COSMIC	8.808	Down-regulation
CMGC_CDK_CDK5_CDK5_ST	Q96KR7	PHACTR3	Q00535	CDK5	S291	R286Q	286	Missense	distal	-5	no	8.927	8.766	EPSD	TCGA;COSMIC	8.808	Loss
CMGC_CDK_CDK5_CDK5_ST	Q96KR7	PHACTR3	Q00535	CDK5	S318	R322L	322	Missense	distal	4	no	19.725	19.625	PhosphoSitePlus	TCGA	8.808	Down-regulation
CMGC_CDK_CDK5_CDK5_ST	Q96KR7	PHACTR3	Q00535	CDK5	S318	E314K	314	Missense	distal	-4	no	19.725	20.228	PhosphoSitePlus	TCGA;COSMIC	8.808	Up-regulation
CMGC_CDK_CDK5_CDK5_ST	Q96KR7	PHACTR3	Q00535	CDK5	S318	R322Q	322	Missense	distal	4	no	19.725	19.679	PhosphoSitePlus	TCGA;COSMIC	8.808	Down-regulation
CMGC_CDK_CDK5_CDK5_ST	Q96KR7	PHACTR3	Q00535	CDK5	S318	G317E	317	Missense	proximal	-1	no	19.725	19.726	PhosphoSitePlus	TCGA;COSMIC	8.808	Up-regulation
CMGC_CDK_CDK5_CDK5_ST	Q96KR7	PHACTR3	Q00535	CDK5	S328	R322L	322	Missense	distal	-6	no	9.417	9.289	EPSD	TCGA	8.808	Down-regulation
CMGC_CDK_CDK5_CDK5_ST	Q96KR7	PHACTR3	Q00535	CDK5	S328	T330M	330	Missense	proximal	2	no	9.417	9.219	EPSD	TCGA;COSMIC	8.808	Down-regulation
CMGC_CDK_CDK5_CDK5_ST	Q96KR7	PHACTR3	Q00535	CDK5	S328	R322Q	322	Missense	distal	-6	no	9.417	9.360	EPSD	TCGA;COSMIC	8.808	Down-regulation
CMGC_CDK_CDK5_CDK5_ST	P01106	MYC	Q00535	CDK5	T58	E54D	54	Missense	distal	-4	no	15.918	15.870	EPSD	TCGA;ICGC;COSMIC;GDSC	8.808	Down-regulation
CMGC_CDK_CDK5_CDK5_ST	P01106	MYC	Q00535	CDK5	S161	S161L	161	Missense	central	0	yes	19.094	0.000	EPSD	TCGA;ICGC;COSMIC	8.808	Loss
CMGC_CDK_CDK5_CDK5_ST	P01106	MYC	Q00535	CDK5	S204	S207L	207	Missense	distal	3	no	18.353	17.301	EPSD	TCGA;ICGC;COSMIC	8.808	Down-regulation
CMGC_CDK_CDK5_CDK5_ST	P01106	MYC	Q00535	CDK5	S337	K341R	341	Missense	distal	4	no	9.652	9.604	EPSD	TCGA;ICGC;COSMIC	8.808	Down-regulation
CMGC_CDK_CDK5_CDK5_ST	P01106	MYC	Q00535	CDK5	S344	K341R	341	Missense	distal	-3	no	17.132	17.113	EPSD	TCGA;ICGC;COSMIC	8.808	Down-regulation
CMGC_CDK_CDK5_CDK5_ST	Q14195	DPYSL3	Q00535	CDK5	T509	P510S	510	Missense	proximal	1	no	17.034	5.133	EPSD	TCGA;COSMIC	8.808	Loss
CMGC_CDK_CDK5_CDK5_ST	Q14195	DPYSL3	Q00535	CDK5	T509	G513R	513	Missense	distal	4	no	17.034	17.102	EPSD	TCGA;COSMIC	8.808	Up-regulation
CMGC_CDK_CDK5_CDK5_ST	Q14195	DPYSL3	Q00535	CDK5	T514	P510S	510	Missense	distal	-4	no	17.300	17.646	EPSD	TCGA;COSMIC	8.808	Up-regulation
CMGC_CDK_CDK5_CDK5_ST	Q14195	DPYSL3	Q00535	CDK5	T514	G513R	513	Missense	proximal	-1	no	17.300	17.304	EPSD	TCGA;COSMIC	8.808	Up-regulation
CMGC_CDK_CDK5_CDK5_ST	P09874	PARP1	Q00535	CDK5	S25	E26Q	26	Missense	proximal	1	no	-3.704	9.531	EPSD	TCGA;ICGC;COSMIC;CCLE	8.808	Gain
CMGC_CDK_CDK5_CDK5_ST	P09874	PARP1	Q00535	CDK5	S41	S41L	41	Missense	central	0	yes	16.170	0.000	EPSD	TCGA;ICGC;COSMIC	8.808	Loss
CMGC_CDK_CDK5_CDK5_ST	P09874	PARP1	Q00535	CDK5	S179	P174T	174	Missense	distal	-5	no	10.289	10.286	EPSD	TCGA;ICGC;COSMIC	8.808	Down-regulation
CMGC_CDK_CDK5_CDK5_ST	P09874	PARP1	Q00535	CDK5	S179	A178V	178	Missense	proximal	-1	no	10.289	10.292	EPSD	TCGA;ICGC;COSMIC;GDSC;CCLE	8.808	Up-regulation
CMGC_CDK_CDK5_CDK5_ST	P09874	PARP1	Q00535	CDK5	T368	T368M	368	Missense	central	0	yes	17.579	0.000	EPSD	TCGA;GDSC;CCLE	8.808	Loss
CMGC_CDK_CDK5_CDK5_ST	P09874	PARP1	Q00535	CDK5	T368	A363T	363	Missense	distal	-5	no	17.579	17.735	EPSD	TCGA;ICGC;COSMIC	8.808	Up-regulation
CMGC_CDK_CDK5_CDK5_ST	P09874	PARP1	Q00535	CDK5	T368	P369L	369	Missense	proximal	1	no	17.579	5.629	EPSD	TCGA;ICGC;COSMIC	8.808	Loss
CMGC_CDK_CDK5_CDK5_ST	P09874	PARP1	Q00535	CDK5	T368	S375L	375	Missense	distal	7	no	17.579	17.567	EPSD	TCGA;ICGC;COSMIC	8.808	Down-regulation
CMGC_CDK_CDK5_CDK5_ST	P09874	PARP1	Q00535	CDK5	T368	P371L	371	Missense	distal	3	no	17.579	16.507	EPSD	TCGA;ICGC;COSMIC	8.808	Down-regulation
CMGC_CDK_CDK5_CDK5_ST	P09874	PARP1	Q00535	CDK5	T368	V365M	365	Missense	distal	-3	no	17.579	17.523	EPSD	TCGA;ICGC;COSMIC	8.808	Down-regulation
CMGC_CDK_CDK5_CDK5_ST	P09874	PARP1	Q00535	CDK5	S479	H476R	476	Missense	distal	-3	no	17.232	17.264	EPSD	TCGA;ICGC	8.808	Up-regulation
CMGC_CDK_CDK5_CDK5_ST	P09874	PARP1	Q00535	CDK5	S479	F473L	473	Missense	distal	-6	no	17.232	17.283	EPSD	TCGA;ICGC;COSMIC	8.808	Up-regulation
CMGC_CDK_CDK5_CDK5_ST	P09874	PARP1	Q00535	CDK5	S479	A475V	475	Missense	distal	-4	no	17.232	17.652	EPSD	TCGA;ICGC	8.808	Up-regulation
CMGC_CDK_CDK5_CDK5_ST	P09874	PARP1	Q00535	CDK5	S721	A719V	719	Missense	proximal	-2	no	8.778	8.974	EPSD	TCGA;COSMIC	8.808	Gain
CMGC_CDK_CDK5_CDK5_ST	Q16555	DPYSL2	Q00535	CDK5	S304	F301V	301	Missense	distal	-3	no	16.977	17.045	EPSD	TCGA;COSMIC	8.808	Up-regulation
CMGC_CDK_CDK5_CDK5_ST	Q16555	DPYSL2	Q00535	CDK5	S308	F301V	301	Missense	distal	-7	no	18.358	18.424	EPSD	TCGA;COSMIC	8.808	Up-regulation
CMGC_CDK_CDK5_CDK5_ST	Q16555	DPYSL2	Q00535	CDK5	S442	G436D	436	Missense	distal	-6	no	16.852	16.850	EPSD	TCGA	8.808	Down-regulation
CMGC_CDK_CDK5_CDK5_ST	Q16555	DPYSL2	Q00535	CDK5	S442	R440C	440	Missense	proximal	-2	no	16.852	16.335	EPSD	TCGA;COSMIC	8.808	Down-regulation
CMGC_CDK_CDK5_CDK5_ST	Q16555	DPYSL2	Q00535	CDK5	S442	Q449K	449	Missense	distal	7	no	16.852	16.863	EPSD	TCGA;COSMIC	8.808	Up-regulation
CMGC_CDK_CDK5_CDK5_ST	Q16555	DPYSL2	Q00535	CDK5	S448	Q449K	449	Missense	proximal	1	no	9.617	0.415	EPSD	TCGA;COSMIC	8.808	Loss
CMGC_CDK_CDK5_CDK5_ST	Q16555	DPYSL2	Q00535	CDK5	T509	V513I	513	Missense	distal	4	no	17.252	17.228	EPSD	TCGA;COSMIC	8.808	Down-regulation
CMGC_CDK_CDK5_CDK5_ST	Q16555	DPYSL2	Q00535	CDK5	T509	T509M	509	Missense	central	0	yes	17.252	0.000	EPSD	TCGA;COSMIC	8.808	Loss
CMGC_CDK_CDK5_CDK5_ST	Q16555	DPYSL2	Q00535	CDK5	T509	P515S	515	Missense	distal	6	no	17.252	17.253	EPSD	TCGA;COSMIC	8.808	Up-regulation
CMGC_CDK_CDK5_CDK5_ST	Q16555	DPYSL2	Q00535	CDK5	T514	V513I	513	Missense	proximal	-1	no	17.700	17.699	EPSD	TCGA;COSMIC	8.808	Down-regulation
CMGC_CDK_CDK5_CDK5_ST	Q16555	DPYSL2	Q00535	CDK5	T514	T509M	509	Missense	distal	-5	no	17.700	17.443	EPSD	TCGA;COSMIC	8.808	Down-regulation
CMGC_CDK_CDK5_CDK5_ST	Q16555	DPYSL2	Q00535	CDK5	T514	P515S	515	Missense	proximal	1	no	17.700	5.799	EPSD	TCGA;COSMIC	8.808	Loss
CMGC_CDK_CDK5_CDK5_ST	Q16555	DPYSL2	Q00535	CDK5	T514	T521M	521	Missense	distal	7	no	17.700	17.687	EPSD	TCGA;COSMIC	8.808	Down-regulation
CMGC_CDK_CDK5_CDK5_ST	Q16555	DPYSL2	Q00535	CDK5	S522	P515S	515	Missense	distal	-7	no	20.593	20.598	PhosphoSitePlus	TCGA;COSMIC	8.808	Up-regulation
CMGC_CDK_CDK5_CDK5_ST	Q16555	DPYSL2	Q00535	CDK5	S522	T521M	521	Missense	proximal	-1	no	20.593	20.587	PhosphoSitePlus	TCGA;COSMIC	8.808	Down-regulation
CMGC_CDK_CDK5_CDK5_ST	P27695	APEX1	Q00535	CDK5	T233	A230D	230	Missense	distal	-3	no	17.263	17.269	PhosphoSitePlus	TCGA;ICGC;COSMIC	8.808	Up-regulation
CMGC_CDK_CDK5_CDK5_ST	P27695	APEX1	Q00535	CDK5	T233	A230T	230	Missense	distal	-3	no	17.263	17.308	PhosphoSitePlus	TCGA;ICGC;COSMIC	8.808	Up-regulation
CMGC_CDK_CDK5_CDK5_ST	P06400	RB1	Q00535	CDK5	S230	F226L	226	Missense	distal	-4	no	15.282	15.623	EPSD	TCGA;ICGC;COSMIC	8.808	Up-regulation
CMGC_CDK_CDK5_CDK5_ST	P06400	RB1	Q00535	CDK5	S230	Y225C	225	Missense	distal	-5	no	15.282	15.257	EPSD	TCGA;ICGC	8.808	Down-regulation
CMGC_CDK_CDK5_CDK5_ST	P06400	RB1	Q00535	CDK5	S249	R255Q	255	Missense	distal	6	no	19.717	19.706	EPSD	TCGA;ICGC;COSMIC	8.808	Down-regulation
CMGC_CDK_CDK5_CDK5_ST	P06400	RB1	Q00535	CDK5	S249	R251Q	251	Missense	proximal	2	no	19.717	19.578	EPSD	TCGA;ICGC;COSMIC;CCLE	8.808	Down-regulation
CMGC_CDK_CDK5_CDK5_ST	P06400	RB1	Q00535	CDK5	S249	P245A	245	Missense	distal	-4	no	19.717	19.162	EPSD	TCGA;ICGC;COSMIC	8.808	Down-regulation
CMGC_CDK_CDK5_CDK5_ST	P06400	RB1	Q00535	CDK5	T252	R255Q	255	Missense	distal	3	no	18.798	16.995	EPSD	TCGA;ICGC;COSMIC	8.808	Down-regulation
CMGC_CDK_CDK5_CDK5_ST	P06400	RB1	Q00535	CDK5	T252	R251Q	251	Missense	proximal	-1	no	18.798	18.796	EPSD	TCGA;ICGC;COSMIC;CCLE	8.808	Down-regulation
CMGC_CDK_CDK5_CDK5_ST	P06400	RB1	Q00535	CDK5	T252	P245A	245	Missense	distal	-7	no	18.798	18.748	EPSD	TCGA;ICGC;COSMIC	8.808	Down-regulation
CMGC_CDK_CDK5_CDK5_ST	P06400	RB1	Q00535	CDK5	T252	R259S	259	Missense	distal	7	no	18.798	18.796	EPSD	TCGA;ICGC;COSMIC	8.808	Down-regulation
CMGC_CDK_CDK5_CDK5_ST	P06400	RB1	Q00535	CDK5	T356	S350I	350	Missense	distal	-6	no	18.896	18.823	EPSD	TCGA;ICGC;COSMIC;GDSC	8.808	Down-regulation
CMGC_CDK_CDK5_CDK5_ST	P06400	RB1	Q00535	CDK5	T373	P374A	374	Missense	proximal	1	no	18.227	7.201	EPSD	TCGA;ICGC;COSMIC	8.808	Loss
CMGC_CDK_CDK5_CDK5_ST	P06400	RB1	Q00535	CDK5	T373	M379L	379	Missense	distal	6	no	18.227	18.229	EPSD	TCGA;ICGC;COSMIC	8.808	Up-regulation
CMGC_CDK_CDK5_CDK5_ST	P06400	RB1	Q00535	CDK5	S567	S567L	567	Missense	central	0	yes	16.330	0.000	EPSD	TCGA;ICGC;COSMIC	8.808	Loss
CMGC_CDK_CDK5_CDK5_ST	P06400	RB1	Q00535	CDK5	S567	W563S	563	Missense	distal	-4	no	16.330	17.140	EPSD	TCGA;ICGC;COSMIC	8.808	Up-regulation
CMGC_CDK_CDK5_CDK5_ST	P06400	RB1	Q00535	CDK5	S567	A562E	562	Missense	distal	-5	no	16.330	16.337	EPSD	TCGA;ICGC;COSMIC	8.808	Up-regulation
CMGC_CDK_CDK5_CDK5_ST	P06400	RB1	Q00535	CDK5	S608	D604G	604	Missense	distal	-4	no	18.641	18.477	EPSD	TCGA;ICGC;COSMIC	8.808	Down-regulation
CMGC_CDK_CDK5_CDK5_ST	P06400	RB1	Q00535	CDK5	S618	S624Y	624	Missense	distal	6	no	9.723	9.709	EPSD	TCGA;ICGC;COSMIC	8.808	Down-regulation
CMGC_CDK_CDK5_CDK5_ST	P06400	RB1	Q00535	CDK5	S618	R621H	621	Missense	distal	3	no	9.723	8.704	EPSD	TCGA;ICGC;COSMIC;CCLE	8.808	Loss
CMGC_CDK_CDK5_CDK5_ST	P06400	RB1	Q00535	CDK5	T620	S624Y	624	Missense	distal	4	no	9.249	9.164	EPSD	TCGA;ICGC;COSMIC	8.808	Down-regulation
CMGC_CDK_CDK5_CDK5_ST	P06400	RB1	Q00535	CDK5	T620	R621H	621	Missense	proximal	1	no	9.249	-0.316	EPSD	TCGA;ICGC;COSMIC;CCLE	8.808	Loss
CMGC_CDK_CDK5_CDK5_ST	P06400	RB1	Q00535	CDK5	S780	I782M	782	Missense	proximal	2	no	18.526	18.423	EPSD	TCGA;ICGC;COSMIC	8.808	Down-regulation
CMGC_CDK_CDK5_CDK5_ST	P06400	RB1	Q00535	CDK5	S780	R787Q	787	Missense	distal	7	no	18.526	18.521	EPSD	TCGA;ICGC;COSMIC	8.808	Down-regulation
CMGC_CDK_CDK5_CDK5_ST	P06400	RB1	Q00535	CDK5	S788	I782M	782	Missense	distal	-6	no	19.412	19.336	EPSD	TCGA;ICGC;COSMIC	8.808	Down-regulation
CMGC_CDK_CDK5_CDK5_ST	P06400	RB1	Q00535	CDK5	S788	S788N	788	Missense	central	0	yes	19.412	0.000	EPSD	TCGA;ICGC;COSMIC	8.808	Loss
CMGC_CDK_CDK5_CDK5_ST	P06400	RB1	Q00535	CDK5	S788	R787Q	787	Missense	proximal	-1	no	19.412	19.410	EPSD	TCGA;ICGC;COSMIC	8.808	Down-regulation
CMGC_CDK_CDK5_CDK5_ST	P06400	RB1	Q00535	CDK5	S795	S788N	788	Missense	distal	-7	no	19.344	19.318	PhosphoSitePlus;EPSD	TCGA;ICGC;COSMIC	8.808	Down-regulation
CMGC_CDK_CDK5_CDK5_ST	P06400	RB1	Q00535	CDK5	S795	R798W	798	Missense	distal	3	no	19.344	17.653	PhosphoSitePlus;EPSD	TCGA;ICGC;COSMIC;GDSC	8.808	Down-regulation
CMGC_CDK_CDK5_CDK5_ST	P06400	RB1	Q00535	CDK5	S807	N803S	803	Missense	distal	-4	no	19.364	19.877	EPSD;PhosphoSitePlus	TCGA;ICGC	8.808	Up-regulation
CMGC_CDK_CDK5_CDK5_ST	P06400	RB1	Q00535	CDK5	T826	P827S	827	Missense	proximal	1	no	17.199	5.298	EPSD	TCGA;ICGC;COSMIC	8.808	Loss
CMGC_CDK_CDK5_CDK5_ST	P06400	RB1	Q00535	CDK5	S866	G865V	865	Missense	proximal	-1	no	9.352	9.355	EPSD	TCGA;ICGC;COSMIC	8.808	Up-regulation
CMGC_CDK_CDK5_CDK5_ST	P06400	RB1	Q00535	CDK5	S866	K860R	860	Missense	distal	-6	no	9.352	9.316	EPSD	TCGA;ICGC;COSMIC	8.808	Down-regulation
CMGC_CDK_CDK5_CDK5_ST	Q16236	NFE2L2	Q00535	CDK5	S40	R34G	34	Missense	distal	-6	no	10.192	10.091	EPSD	TCGA;COSMIC;GDSC;CCLE	8.808	Down-regulation
CMGC_CDK_CDK5_CDK5_ST	Q16236	NFE2L2	Q00535	CDK5	S40	R34P	34	Missense	distal	-6	no	10.192	10.147	EPSD	TCGA;COSMIC	8.808	Down-regulation
CMGC_CDK_CDK5_CDK5_ST	Q16236	NFE2L2	Q00535	CDK5	S40	E35D	35	Missense	distal	-5	no	10.192	10.202	EPSD	TCGA;COSMIC	8.808	Up-regulation
CMGC_CDK_CDK5_CDK5_ST	Q16236	NFE2L2	Q00535	CDK5	S40	R34Q	34	Missense	distal	-6	no	10.192	10.134	EPSD	TCGA;COSMIC;CCLE	8.808	Down-regulation
CMGC_CDK_CDK5_CDK5_ST	Q16236	NFE2L2	Q00535	CDK5	S40	Y46H	46	Missense	distal	6	no	10.192	10.203	EPSD	TCGA	8.808	Up-regulation
CMGC_CDK_CDK5_CDK5_ST	Q16236	NFE2L2	Q00535	CDK5	S40	R34L	34	Missense	distal	-6	no	10.192	10.063	EPSD	TCGA;COSMIC	8.808	Down-regulation
CMGC_CDK_CDK5_CDK5_ST	Q16236	NFE2L2	Q00535	CDK5	S40	D38V	38	Missense	proximal	-2	no	10.192	10.345	EPSD	TCGA	8.808	Up-regulation
CMGC_CDK_CDK5_CDK5_ST	Q16236	NFE2L2	Q00535	CDK5	S40	R43G	43	Missense	distal	3	no	10.192	8.811	EPSD	TCGA;COSMIC	8.808	Down-regulation
CMGC_CDK_CDK5_CDK5_ST	Q16236	NFE2L2	Q00535	CDK5	S215	P214Q	214	Missense	proximal	-1	no	17.627	17.626	EPSD	TCGA;COSMIC	8.808	Down-regulation
CMGC_CDK_CDK5_CDK5_ST	Q16236	NFE2L2	Q00535	CDK5	S351	S347L	347	Missense	distal	-4	no	18.757	17.937	EPSD	TCGA;COSMIC	8.808	Down-regulation
CMGC_CDK_CDK5_CDK5_ST	Q16236	NFE2L2	Q00535	CDK5	S351	G345S	345	Missense	distal	-6	no	18.757	18.852	EPSD	TCGA;COSMIC	8.808	Up-regulation
CMGC_CDK_CDK5_CDK5_ST	Q16236	NFE2L2	Q00535	CDK5	S408	S414N	414	Missense	distal	6	no	17.464	17.459	EPSD	TCGA;COSMIC;GDSC;CCLE	8.808	Down-regulation
CMGC_CDK_CDK5_CDK5_ST	Q16236	NFE2L2	Q00535	CDK5	S408	P406L	406	Missense	proximal	-2	no	17.464	17.049	EPSD	TCGA	8.808	Down-regulation
CMGC_CDK_CDK5_CDK5_ST	Q16236	NFE2L2	Q00535	CDK5	S577	P575L	575	Missense	proximal	-2	no	16.908	16.493	EPSD	TCGA;COSMIC	8.808	Down-regulation
CMGC_CDK_CDK5_CDK5_ST	Q16236	NFE2L2	Q00535	CDK5	S577	D570N	570	Missense	distal	-7	no	16.908	16.926	EPSD	TCGA;COSMIC	8.808	Up-regulation
CMGC_CDK_CDK5_CDK5_ST	Q16236	NFE2L2	Q00535	CDK5	S577	P575S	575	Missense	proximal	-2	no	16.908	16.809	EPSD	TCGA;COSMIC	8.808	Down-regulation
CMGC_CDK_CDK5_CDK5_ST	P35968	KDR	Q00535	CDK5	S229	Y224F	224	Missense	distal	-5	no	18.514	18.434	PhosphoSitePlus	TCGA;ICGC;COSMIC	8.808	Down-regulation
CMGC_CDK_CDK5_CDK5_ST	P35968	KDR	Q00535	CDK5	S229	G233E	233	Missense	distal	4	no	18.514	18.512	PhosphoSitePlus	TCGA;ICGC;COSMIC	8.808	Down-regulation
CMGC_CDK_CDK5_CDK5_ST	P35968	KDR	Q00535	CDK5	T1217	A1218P	1218	Missense	proximal	1	no	5.205	16.231	EPSD	TCGA;ICGC;COSMIC	8.808	Gain
CMGC_CDK_CDK5_CDK5_ST	P35968	KDR	Q00535	CDK5	S1231	V1234M	1234	Missense	distal	3	no	10.206	9.238	EPSD	TCGA;ICGC;COSMIC	8.808	Down-regulation
CMGC_CDK_CDK5_CDK5_ST	P35968	KDR	Q00535	CDK5	S1231	R1229Q	1229	Missense	proximal	-2	no	10.206	10.069	EPSD	TCGA;ICGC;COSMIC	8.808	Down-regulation
CMGC_CDK_CDK5_CDK5_ST	P35968	KDR	Q00535	CDK5	S1231	S1231N	1231	Missense	central	0	yes	10.206	0.000	EPSD	TCGA;ICGC;COSMIC	8.808	Loss
CMGC_CDK_CDK5_CDK5_ST	P35968	KDR	Q00535	CDK5	S1279	S1279F	1279	Missense	central	0	yes	16.619	0.000	EPSD	TCGA;ICGC;COSMIC	8.808	Loss
CMGC_CDK_CDK5_CDK5_ST	P35968	KDR	Q00535	CDK5	S1279	P1280T	1280	Missense	proximal	1	no	16.619	6.132	EPSD	TCGA;ICGC;COSMIC	8.808	Loss
CMGC_CDK_CDK5_CDK5_ST	P35968	KDR	Q00535	CDK5	S1279	M1285T	1285	Missense	distal	6	no	16.619	16.636	EPSD	TCGA;ICGC;COSMIC	8.808	Up-regulation
CMGC_CDK_CDK5_CDK5_ST	P35968	KDR	Q00535	CDK5	S1290	S1290R	1290	Missense	central	0	yes	9.427	0.000	EPSD	TCGA;ICGC;COSMIC	8.808	Loss
CMGC_CDK_CDK5_CDK5_ST	P35968	KDR	Q00535	CDK5	S1290	M1285T	1285	Missense	distal	-5	no	9.427	9.684	EPSD	TCGA;ICGC;COSMIC	8.808	Up-regulation
CMGC_CDK_CDK5_CDK5_ST	P35968	KDR	Q00535	CDK5	S1290	S1296Y	1296	Missense	distal	6	no	9.427	9.412	EPSD	TCGA;ICGC	8.808	Down-regulation
CMGC_CDK_CDK5_CDK5_ST	P35968	KDR	Q00535	CDK5	S1290	S1290I	1290	Missense	central	0	yes	9.427	0.000	EPSD	TCGA;ICGC	8.808	Loss
CMGC_CDK_CDK5_CDK5_ST	P35968	KDR	Q00535	CDK5	S1290	E1292K	1292	Missense	proximal	2	no	9.427	9.677	EPSD	TCGA;ICGC	8.808	Up-regulation
CMGC_CDK_CDK5_CDK5_ST	P35222	CTNNB1	Q00535	CDK5	S33	G34R	34	Missense	proximal	1	no	-2.397	10.072	EPSD	TCGA;COSMIC	8.808	Gain
CMGC_CDK_CDK5_CDK5_ST	P35222	CTNNB1	Q00535	CDK5	S191	A197S	197	Missense	distal	6	no	16.522	16.534	EPSD;PhosphoSitePlus	TCGA;COSMIC	8.808	Up-regulation
CMGC_CDK_CDK5_CDK5_ST	P35222	CTNNB1	Q00535	CDK5	S191	R185G	185	Missense	distal	-6	no	16.522	16.420	EPSD;PhosphoSitePlus	TCGA;COSMIC	8.808	Down-regulation
CMGC_CDK_CDK5_CDK5_ST	P35222	CTNNB1	Q00535	CDK5	T289	K292T	292	Missense	distal	3	no	9.190	8.008	EPSD	TCGA;COSMIC	8.808	Loss
CMGC_CDK_CDK5_CDK5_ST	P35222	CTNNB1	Q00535	CDK5	T289	K292E	292	Missense	distal	3	no	9.190	6.904	EPSD	TCGA;COSMIC	8.808	Loss
CMGC_CDK_CDK5_CDK5_ST	P35222	CTNNB1	Q00535	CDK5	T547	R542H	542	Missense	distal	-5	no	10.356	10.183	EPSD	TCGA;COSMIC	8.808	Down-regulation
CMGC_CDK_CDK5_CDK5_ST	P35222	CTNNB1	Q00535	CDK5	T547	M553V	553	Missense	distal	6	no	10.356	10.370	EPSD	TCGA;COSMIC	8.808	Up-regulation
CMGC_CDK_CDK5_CDK5_ST	P35222	CTNNB1	Q00535	CDK5	T547	V541A	541	Missense	distal	-6	no	10.356	10.286	EPSD	TCGA;COSMIC	8.808	Down-regulation
CMGC_CDK_CDK5_CDK5_ST	P35222	CTNNB1	Q00535	CDK5	S605	P606L	606	Missense	proximal	1	no	17.288	5.339	EPSD	TCGA;COSMIC	8.808	Loss
CMGC_CDK_CDK5_CDK5_ST	Q9UKV5	AMFR	Q00535	CDK5	S516	P521S	521	Missense	distal	5	no	17.792	17.804	PhosphoSitePlus	TCGA;ICGC;COSMIC	8.808	Up-regulation
CMGC_CDK_CDK5_CDK5_ST	P40763	STAT3	Q00535	CDK5	T196	V195L	195	Missense	proximal	-1	no	10.155	10.151	EPSD	TCGA	8.808	Down-regulation
CMGC_CDK_CDK5_CDK5_ST	P40763	STAT3	Q00535	CDK5	T714	S719N	719	Missense	distal	5	no	17.499	17.435	EPSD	TCGA;ICGC	8.808	Down-regulation
CMGC_CDK_CDK5_CDK5_ST	P40763	STAT3	Q00535	CDK5	S727	R729H	729	Missense	proximal	2	no	19.471	19.356	PhosphoSitePlus	TCGA;ICGC;COSMIC;GDSC;CCLE	8.808	Down-regulation
CMGC_CDK_CDK5_CDK5_ST	P40763	STAT3	Q00535	CDK5	S727	P725L	725	Missense	proximal	-2	no	19.471	19.056	PhosphoSitePlus	TCGA;ICGC;COSMIC	8.808	Down-regulation
CMGC_CDK_CDK5_CDK5_ST	Q05193	DNM1	Q00535	CDK5	S116	R123C	123	Missense	distal	7	no	17.961	17.945	EPSD	TCGA	8.808	Down-regulation
CMGC_CDK_CDK5_CDK5_ST	Q05193	DNM1	Q00535	CDK5	S126	R123C	123	Missense	distal	-3	no	18.047	17.969	EPSD	TCGA	8.808	Down-regulation
CMGC_CDK_CDK5_CDK5_ST	Q05193	DNM1	Q00535	CDK5	T274	P275S	275	Missense	proximal	1	no	15.902	4.001	EPSD	TCGA;ICGC;COSMIC	8.808	Loss
CMGC_CDK_CDK5_CDK5_ST	Q05193	DNM1	Q00535	CDK5	T404	E410Q	410	Missense	distal	6	no	16.122	16.128	EPSD	TCGA;ICGC;COSMIC	8.808	Up-regulation
CMGC_CDK_CDK5_CDK5_ST	Q05193	DNM1	Q00535	CDK5	S774	P769L	769	Missense	distal	-5	no	17.473	17.276	EPSD	TCGA;ICGC;COSMIC	8.808	Down-regulation
CMGC_CDK_CDK5_CDK5_ST	Q05193	DNM1	Q00535	CDK5	S851	R854C	854	Missense	distal	3	no	20.799	18.503	EPSD	TCGA	8.808	Down-regulation
CMGC_CDK_CDK5_CDK5_ST	Q05193	DNM1	Q00535	CDK5	S851	R854H	854	Missense	distal	3	no	20.799	19.779	EPSD	TCGA;ICGC	8.808	Down-regulation
CMGC_CDK_CDK5_CDK5_ST	Q05193	DNM1	Q00535	CDK5	S851	R846Q	846	Missense	distal	-5	no	20.799	20.638	EPSD	TCGA;COSMIC;GDSC;CCLE	8.808	Down-regulation
CMGC_CDK_CDK5_CDK5_ST	Q05193	DNM1	Q00535	CDK5	S853	R854C	854	Missense	proximal	1	no	8.972	-2.754	EPSD	TCGA	8.808	Loss
CMGC_CDK_CDK5_CDK5_ST	Q05193	DNM1	Q00535	CDK5	S853	R854H	854	Missense	proximal	1	no	8.972	-0.593	EPSD	TCGA;ICGC	8.808	Loss
CMGC_CDK_CDK5_CDK5_ST	Q05193	DNM1	Q00535	CDK5	S853	R846Q	846	Missense	distal	-7	no	8.972	8.952	EPSD	TCGA;COSMIC;GDSC;CCLE	8.808	Down-regulation
CMGC_CDK_CDK5_CDK5_ST	Q05193	DNM1	Q00535	CDK5	S857	R854C	854	Missense	distal	-3	no	19.199	19.120	EPSD	TCGA	8.808	Down-regulation
CMGC_CDK_CDK5_CDK5_ST	Q05193	DNM1	Q00535	CDK5	S857	R854H	854	Missense	distal	-3	no	19.199	19.167	EPSD	TCGA;ICGC	8.808	Down-regulation
CMGC_CDK_CDK5_CDK5_ST	Q96C19	EFHD2	Q00535	CDK5	S74	V79I	79	Missense	distal	5	no	19.393	19.341	PhosphoSitePlus	TCGA;ICGC;COSMIC	8.808	Down-regulation
CMGC_CDK_CDK5_CDK5_ST	Q96C19	EFHD2	Q00535	CDK5	S76	V79I	79	Missense	distal	3	no	9.599	9.150	EPSD	TCGA;ICGC;COSMIC	8.808	Down-regulation
CMGC_CDK_CDK5_CDK5_ST	Q96C19	EFHD2	Q00535	CDK5	S90	Q93H	93	Missense	distal	3	no	8.538	9.322	EPSD	TCGA;ICGC;COSMIC	8.808	Gain
CMGC_CDK_CDK5_CDK5_ST	Q02078	MEF2A	Q00535	CDK5	S98	D100Y	100	Missense	proximal	2	no	16.877	16.832	EPSD	TCGA;ICGC;COSMIC	8.808	Down-regulation
CMGC_CDK_CDK5_CDK5_ST	Q02078	MEF2A	Q00535	CDK5	S181	L180F	180	Missense	proximal	-1	no	17.456	17.454	EPSD	TCGA;ICGC;COSMIC	8.808	Down-regulation
CMGC_CDK_CDK5_CDK5_ST	Q02078	MEF2A	Q00535	CDK5	S192	P196S	196	Missense	distal	4	no	17.180	17.182	EPSD	TCGA;COSMIC	8.808	Up-regulation
CMGC_CDK_CDK5_CDK5_ST	Q02078	MEF2A	Q00535	CDK5	S192	S192F	192	Missense	central	0	yes	17.180	0.000	EPSD	TCGA;COSMIC	8.808	Loss
CMGC_CDK_CDK5_CDK5_ST	Q02078	MEF2A	Q00535	CDK5	S223	G219A	219	Missense	distal	-4	no	17.690	17.630	EPSD	TCGA;COSMIC	8.808	Down-regulation
CMGC_CDK_CDK5_CDK5_ST	Q02078	MEF2A	Q00535	CDK5	S223	F229C	229	Missense	distal	6	no	17.690	17.694	EPSD	TCGA;ICGC;COSMIC	8.808	Up-regulation
CMGC_CDK_CDK5_CDK5_ST	Q02078	MEF2A	Q00535	CDK5	S235	S235F	235	Missense	central	0	yes	17.057	0.000	EPSD	TCGA;ICGC;COSMIC	8.808	Loss
CMGC_CDK_CDK5_CDK5_ST	Q02078	MEF2A	Q00535	CDK5	S235	F229C	229	Missense	distal	-6	no	17.057	17.084	EPSD	TCGA;ICGC;COSMIC	8.808	Up-regulation
CMGC_CDK_CDK5_CDK5_ST	Q02078	MEF2A	Q00535	CDK5	S235	N237K	237	Missense	proximal	2	no	17.057	17.251	EPSD	TCGA;COSMIC	8.808	Up-regulation
CMGC_CDK_CDK5_CDK5_ST	Q02078	MEF2A	Q00535	CDK5	S255	G260V	260	Missense	distal	5	no	17.774	17.840	EPSD	TCGA;ICGC;COSMIC	8.808	Up-regulation
CMGC_CDK_CDK5_CDK5_ST	Q02078	MEF2A	Q00535	CDK5	S255	P258A	258	Missense	distal	3	no	17.774	17.529	EPSD	TCGA;COSMIC	8.808	Down-regulation
CMGC_CDK_CDK5_CDK5_ST	Q02078	MEF2A	Q00535	CDK5	S255	P257L	257	Missense	proximal	2	no	17.774	17.608	EPSD	TCGA;COSMIC	8.808	Down-regulation
CMGC_CDK_CDK5_CDK5_ST	Q02078	MEF2A	Q00535	CDK5	S268	R274Q	274	Missense	distal	6	no	8.963	8.952	EPSD	TCGA;ICGC;COSMIC	8.808	Down-regulation
CMGC_CDK_CDK5_CDK5_ST	Q02078	MEF2A	Q00535	CDK5	S268	L264I	264	Missense	distal	-4	no	8.963	9.167	EPSD	TCGA;ICGC	8.808	Up-regulation
CMGC_CDK_CDK5_CDK5_ST	Q00535	CDK5	Q00535	CDK5	S72	D73N	73	Missense	proximal	1	no	9.325	10.791	EPSD	TCGA;ICGC;COSMIC	8.808	Up-regulation
CMGC_CDK_CDK5_CDK5_ST	P41236	PPP1R2	Q00535	CDK5	T73	E70K	70	Missense	distal	-3	no	17.425	17.497	PhosphoSitePlus	TCGA;ICGC;COSMIC	8.808	Up-regulation
CMGC_CDK_CDK5_CDK5_ST	O43464	HTRA2	Q00535	CDK5	T54	R60W	60	Missense	distal	6	no	16.127	16.110	EPSD	TCGA;ICGC;COSMIC;CCLE	8.808	Down-regulation
CMGC_CDK_CDK5_CDK5_ST	O43464	HTRA2	Q00535	CDK5	S352	G353R	353	Missense	proximal	1	no	-3.274	9.195	EPSD	TCGA;COSMIC;GDSC;CCLE	8.808	Gain
CMGC_CDK_CDK5_CDK5_ST	O43464	HTRA2	Q00535	CDK5	S435	A430V	430	Missense	distal	-5	no	8.695	8.820	EPSD	TCGA	8.808	Gain
CMGC_CDK_CDK5_CDK5_ST	P29474	NOS3	Q00535	CDK5	T33	R40W	40	Missense	distal	7	no	17.026	17.015	EPSD	TCGA;ICGC	8.808	Down-regulation
CMGC_CDK_CDK5_CDK5_ST	P29474	NOS3	Q00535	CDK5	S53	T60N	60	Missense	distal	7	no	17.923	17.920	EPSD	TCGA;ICGC;COSMIC	8.808	Down-regulation
CMGC_CDK_CDK5_CDK5_ST	P29474	NOS3	Q00535	CDK5	S53	S53I	53	Missense	central	0	yes	17.923	0.000	EPSD	TCGA;ICGC;COSMIC	8.808	Loss
CMGC_CDK_CDK5_CDK5_ST	P29474	NOS3	Q00535	CDK5	S53	P55L	55	Missense	proximal	2	no	17.923	17.757	EPSD	TCGA;ICGC;COSMIC	8.808	Down-regulation
CMGC_CDK_CDK5_CDK5_ST	P29474	NOS3	Q00535	CDK5	S57	T60N	60	Missense	distal	3	no	19.339	18.587	EPSD	TCGA;ICGC;COSMIC	8.808	Down-regulation
CMGC_CDK_CDK5_CDK5_ST	P29474	NOS3	Q00535	CDK5	S57	S53I	53	Missense	distal	-4	no	19.339	18.724	EPSD	TCGA;ICGC;COSMIC	8.808	Down-regulation
CMGC_CDK_CDK5_CDK5_ST	P29474	NOS3	Q00535	CDK5	S57	P63S	63	Missense	distal	6	no	19.339	19.340	EPSD	TCGA;ICGC;COSMIC	8.808	Up-regulation
CMGC_CDK_CDK5_CDK5_ST	P29474	NOS3	Q00535	CDK5	S57	P55L	55	Missense	proximal	-2	no	19.339	18.924	EPSD	TCGA;ICGC;COSMIC	8.808	Down-regulation
CMGC_CDK_CDK5_CDK5_ST	P29474	NOS3	Q00535	CDK5	T60	T60N	60	Missense	central	0	yes	9.456	0.000	EPSD	TCGA;ICGC;COSMIC	8.808	Loss
CMGC_CDK_CDK5_CDK5_ST	P29474	NOS3	Q00535	CDK5	T60	S53I	53	Missense	distal	-7	no	9.456	9.422	EPSD	TCGA;ICGC;COSMIC	8.808	Down-regulation
CMGC_CDK_CDK5_CDK5_ST	P29474	NOS3	Q00535	CDK5	T60	P63S	63	Missense	distal	3	no	9.456	9.436	EPSD	TCGA;ICGC;COSMIC	8.808	Down-regulation
CMGC_CDK_CDK5_CDK5_ST	P29474	NOS3	Q00535	CDK5	T60	P55L	55	Missense	distal	-5	no	9.456	9.258	EPSD	TCGA;ICGC;COSMIC	8.808	Down-regulation
CMGC_CDK_CDK5_CDK5_ST	P29474	NOS3	Q00535	CDK5	S114	P118L	118	Missense	distal	4	no	17.821	17.739	PhosphoSitePlus	TCGA;ICGC;COSMIC	8.808	Down-regulation
CMGC_CDK_CDK5_CDK5_ST	P29474	NOS3	Q00535	CDK5	S470	P471L	471	Missense	proximal	1	no	15.797	3.847	EPSD	TCGA;ICGC;COSMIC	8.808	Loss
CMGC_CDK_CDK5_CDK5_ST	P29474	NOS3	Q00535	CDK5	S600	S600F	600	Missense	central	0	yes	17.366	0.000	EPSD	TCGA;ICGC;COSMIC	8.808	Loss
CMGC_CDK_CDK5_CDK5_ST	P29474	NOS3	Q00535	CDK5	S600	P601L	601	Missense	proximal	1	no	17.366	5.417	EPSD	TCGA;ICGC;COSMIC	8.808	Loss
CMGC_CDK_CDK5_CDK5_ST	P29474	NOS3	Q00535	CDK5	S725	R721Q	721	Missense	distal	-4	no	20.256	20.246	EPSD	TCGA;ICGC;COSMIC	8.808	Down-regulation
CMGC_CDK_CDK5_CDK5_ST	P29474	NOS3	Q00535	CDK5	S836	P842L	842	Missense	distal	6	no	18.240	18.226	EPSD	TCGA;ICGC;COSMIC	8.808	Down-regulation
CMGC_CDK_CDK5_CDK5_ST	P29474	NOS3	Q00535	CDK5	S836	P841L	841	Missense	distal	5	no	18.240	18.067	EPSD	TCGA;ICGC;COSMIC;GDSC;CCLE	8.808	Down-regulation
CMGC_CDK_CDK5_CDK5_ST	P29474	NOS3	Q00535	CDK5	S836	G838D	838	Missense	proximal	2	no	18.240	18.207	EPSD	TCGA;ICGC	8.808	Down-regulation
CMGC_CDK_CDK5_CDK5_ST	P29474	NOS3	Q00535	CDK5	S870	D864N	864	Missense	distal	-6	no	16.752	16.791	EPSD	TCGA;ICGC;COSMIC	8.808	Up-regulation
CMGC_CDK_CDK5_CDK5_ST	P29474	NOS3	Q00535	CDK5	S870	S867T	867	Missense	distal	-3	no	16.752	16.750	EPSD	TCGA;ICGC;COSMIC	8.808	Down-regulation
CMGC_CDK_CDK5_CDK5_ST	P29474	NOS3	Q00535	CDK5	S870	R875W	875	Missense	distal	5	no	16.752	16.575	EPSD	TCGA;ICGC;COSMIC	8.808	Down-regulation
CMGC_CDK_CDK5_CDK5_ST	P26358	DNMT1	Q00535	CDK5	S127	D124H	124	Missense	distal	-3	no	18.776	18.800	EPSD	TCGA;ICGC;COSMIC	8.808	Up-regulation
CMGC_CDK_CDK5_CDK5_ST	P26358	DNMT1	Q00535	CDK5	S714	M712I	712	Missense	proximal	-2	no	19.235	19.486	EPSD	TCGA;ICGC;COSMIC	8.808	Up-regulation
CMGC_CDK_CDK5_CDK5_ST	Q13315	ATM	Q00535	CDK5	S89	K93N	93	Missense	distal	4	no	11.716	11.621	EPSD	TCGA;ICGC;COSMIC	8.808	Down-regulation
CMGC_CDK_CDK5_CDK5_ST	Q13315	ATM	Q00535	CDK5	T297	P292L	292	Missense	distal	-5	no	10.053	9.855	EPSD	TCGA;ICGC;COSMIC	8.808	Down-regulation
CMGC_CDK_CDK5_CDK5_ST	Q13315	ATM	Q00535	CDK5	T297	E299D	299	Missense	proximal	2	no	10.053	10.049	EPSD	TCGA;ICGC;COSMIC	8.808	Down-regulation
CMGC_CDK_CDK5_CDK5_ST	Q13315	ATM	Q00535	CDK5	T297	A295P	295	Missense	proximal	-2	no	10.053	10.430	EPSD	TCGA;ICGC;COSMIC	8.808	Up-regulation
CMGC_CDK_CDK5_CDK5_ST	Q13315	ATM	Q00535	CDK5	T297	H290Y	290	Missense	distal	-7	no	10.053	10.018	EPSD	TCGA;ICGC;COSMIC	8.808	Down-regulation
CMGC_CDK_CDK5_CDK5_ST	Q13315	ATM	Q00535	CDK5	T297	K296R	296	Missense	proximal	-1	no	10.053	10.051	EPSD	TCGA;ICGC	8.808	Down-regulation
CMGC_CDK_CDK5_CDK5_ST	Q13315	ATM	Q00535	CDK5	T297	G301S	301	Missense	distal	4	no	10.053	10.104	EPSD	TCGA;ICGC;COSMIC	8.808	Up-regulation
CMGC_CDK_CDK5_CDK5_ST	Q13315	ATM	Q00535	CDK5	T373	Q368E	368	Missense	distal	-5	no	9.053	8.959	EPSD	TCGA;ICGC;COSMIC	8.808	Down-regulation
CMGC_CDK_CDK5_CDK5_ST	Q13315	ATM	Q00535	CDK5	S794	S800F	800	Missense	distal	6	no	19.473	19.453	PhosphoSitePlus	TCGA;ICGC;COSMIC	8.808	Down-regulation
CMGC_CDK_CDK5_CDK5_ST	Q13315	ATM	Q00535	CDK5	S1105	L1111I	1111	Missense	distal	6	no	9.089	9.097	EPSD	TCGA;ICGC;COSMIC	8.808	Up-regulation
CMGC_CDK_CDK5_CDK5_ST	Q13315	ATM	Q00535	CDK5	S1770	L1764I	1764	Missense	distal	-6	no	11.116	11.165	EPSD	TCGA;ICGC;COSMIC	8.808	Up-regulation
CMGC_CDK_CDK5_CDK5_ST	Q13315	ATM	Q00535	CDK5	S1770	R1768G	1768	Missense	proximal	-2	no	11.116	10.706	EPSD	TCGA;ICGC;COSMIC	8.808	Down-regulation
CMGC_CDK_CDK5_CDK5_ST	Q13315	ATM	Q00535	CDK5	T1885	R1882Q	1882	Missense	distal	-3	no	17.580	17.554	EPSD	TCGA;ICGC;COSMIC	8.808	Down-regulation
CMGC_CDK_CDK5_CDK5_ST	Q9UQL6	HDAC5	Q00535	CDK5	S3	P4S	4	Missense	proximal	1	no	16.820	4.919	EPSD	TCGA;ICGC;COSMIC	8.808	Loss
CMGC_CDK_CDK5_CDK5_ST	Q9UQL6	HDAC5	Q00535	CDK5	S53	G52E	52	Missense	proximal	-1	no	16.933	16.934	EPSD	TCGA;ICGC;COSMIC	8.808	Up-regulation
CMGC_CDK_CDK5_CDK5_ST	Q9UQL6	HDAC5	Q00535	CDK5	S55	G52E	52	Missense	distal	-3	no	16.748	16.751	EPSD	TCGA;ICGC;COSMIC	8.808	Up-regulation
CMGC_CDK_CDK5_CDK5_ST	Q9UQL6	HDAC5	Q00535	CDK5	T199	L192F	192	Missense	distal	-7	no	17.440	17.412	EPSD	TCGA;ICGC;COSMIC	8.808	Down-regulation
CMGC_CDK_CDK5_CDK5_ST	Q5S007	LRRK2	Q00535	CDK5	T213	L209S	209	Missense	distal	-4	no	9.203	10.022	EPSD	TCGA;ICGC;COSMIC	8.808	Up-regulation
CMGC_CDK_CDK5_CDK5_ST	Q5S007	LRRK2	Q00535	CDK5	T358	W359R	359	Missense	proximal	1	no	-0.934	8.925	EPSD	TCGA;ICGC;COSMIC	8.808	Gain
CMGC_CDK_CDK5_CDK5_ST	Q5S007	LRRK2	Q00535	CDK5	T424	L425P	425	Missense	proximal	1	no	4.691	16.640	EPSD	TCGA;ICGC;COSMIC	8.808	Gain
CMGC_CDK_CDK5_CDK5_ST	Q5S007	LRRK2	Q00535	CDK5	T838	L839P	839	Missense	proximal	1	no	7.307	19.256	EPSD	TCGA;ICGC;COSMIC	8.808	Gain
CMGC_CDK_CDK5_CDK5_ST	Q5S007	LRRK2	Q00535	CDK5	S926	Q923E	923	Missense	distal	-3	no	15.919	15.893	EPSD	TCGA;ICGC;COSMIC	8.808	Down-regulation
CMGC_CDK_CDK5_CDK5_ST	Q5S007	LRRK2	Q00535	CDK5	S926	R924S	924	Missense	proximal	-2	no	15.919	15.875	EPSD	TCGA;ICGC;COSMIC	8.808	Down-regulation
CMGC_CDK_CDK5_CDK5_ST	Q5S007	LRRK2	Q00535	CDK5	S926	L929F	929	Missense	distal	3	no	15.919	15.793	EPSD	TCGA;ICGC;COSMIC	8.808	Down-regulation
CMGC_CDK_CDK5_CDK5_ST	Q5S007	LRRK2	Q00535	CDK5	S926	Q923H	923	Missense	distal	-3	no	15.919	15.914	EPSD	TCGA;ICGC;COSMIC	8.808	Down-regulation
CMGC_CDK_CDK5_CDK5_ST	Q5S007	LRRK2	Q00535	CDK5	S1124	S1124F	1124	Missense	central	0	yes	19.561	0.000	EPSD	TCGA;ICGC;COSMIC	8.808	Loss
CMGC_CDK_CDK5_CDK5_ST	Q5S007	LRRK2	Q00535	CDK5	S1445	G1451D	1451	Missense	distal	6	no	17.728	17.727	EPSD	TCGA;ICGC;COSMIC	8.808	Down-regulation
CMGC_CDK_CDK5_CDK5_ST	Q5S007	LRRK2	Q00535	CDK5	S1445	A1442T	1442	Missense	distal	-3	no	17.728	17.773	EPSD	TCGA;ICGC;COSMIC	8.808	Up-regulation
CMGC_CDK_CDK5_CDK5_ST	Q5S007	LRRK2	Q00535	CDK5	S1445	R1441C	1441	Missense	distal	-4	no	17.728	17.165	EPSD	TCGA;ICGC;COSMIC	8.808	Down-regulation
CMGC_CDK_CDK5_CDK5_ST	Q5S007	LRRK2	Q00535	CDK5	S1457	D1458N	1458	Missense	proximal	1	no	9.176	10.643	EPSD	TCGA;ICGC;COSMIC	8.808	Up-regulation
CMGC_CDK_CDK5_CDK5_ST	Q5S007	LRRK2	Q00535	CDK5	S1457	R1462C	1462	Missense	distal	5	no	9.176	8.920	EPSD	TCGA;ICGC;COSMIC	8.808	Down-regulation
CMGC_CDK_CDK5_CDK5_ST	Q5S007	LRRK2	Q00535	CDK5	S1457	G1451D	1451	Missense	distal	-6	no	9.176	9.174	EPSD	TCGA;ICGC;COSMIC	8.808	Down-regulation
CMGC_CDK_CDK5_CDK5_ST	Q5S007	LRRK2	Q00535	CDK5	S1457	R1462H	1462	Missense	distal	5	no	9.176	9.073	EPSD	TCGA;ICGC;COSMIC;GDSC;CCLE	8.808	Down-regulation
CMGC_CDK_CDK5_CDK5_ST	Q5S007	LRRK2	Q00535	CDK5	S1457	A1464S	1464	Missense	distal	7	no	9.176	9.186	EPSD	TCGA;ICGC	8.808	Up-regulation
CMGC_CDK_CDK5_CDK5_ST	Q5S007	LRRK2	Q00535	CDK5	S1457	S1457Y	1457	Missense	central	0	yes	9.176	0.000	EPSD	TCGA;ICGC;COSMIC	8.808	Loss
CMGC_CDK_CDK5_CDK5_ST	Q5S007	LRRK2	Q00535	CDK5	S1627	S1627A	1627	Missense	central	0	yes	9.543	0.000	PhosphoSitePlus	TCGA;ICGC;COSMIC	8.808	Loss
CMGC_CDK_CDK5_CDK5_ST	Q5S007	LRRK2	Q00535	CDK5	S1627	F1634C	1634	Missense	distal	7	no	9.543	9.545	PhosphoSitePlus	TCGA;ICGC;COSMIC	8.808	Up-regulation
CMGC_CDK_CDK5_CDK5_ST	Q5S007	LRRK2	Q00535	CDK5	S1627	F1634I	1634	Missense	distal	7	no	9.543	9.553	PhosphoSitePlus	TCGA;ICGC;COSMIC	8.808	Up-regulation
CMGC_CDK_CDK5_CDK5_ST	Q5S007	LRRK2	Q00535	CDK5	S1627	R1629I	1629	Missense	proximal	2	no	9.543	9.373	PhosphoSitePlus	TCGA;ICGC;COSMIC	8.808	Down-regulation
CMGC_CDK_CDK5_CDK5_ST	Q5S007	LRRK2	Q00535	CDK5	S1853	S1853Y	1853	Missense	central	0	yes	9.151	0.000	EPSD	TCGA;ICGC;COSMIC	8.808	Loss
CMGC_CDK_CDK5_CDK5_ST	Q5S007	LRRK2	Q00535	CDK5	T1912	S1913P	1913	Missense	proximal	1	no	6.276	18.177	EPSD	TCGA;ICGC	8.808	Gain
CMGC_CDK_CDK5_CDK5_ST	Q5S007	LRRK2	Q00535	CDK5	T2035	R2039C	2039	Missense	distal	4	no	16.072	15.964	EPSD	TCGA;ICGC;COSMIC	8.808	Down-regulation
CMGC_CDK_CDK5_CDK5_ST	Q5S007	LRRK2	Q00535	CDK5	T2035	E2033K	2033	Missense	proximal	-2	no	16.072	16.485	EPSD	TCGA;ICGC	8.808	Up-regulation
CMGC_CDK_CDK5_CDK5_ST	Q5S007	LRRK2	Q00535	CDK5	S2465	L2466P	2466	Missense	proximal	1	no	5.201	17.151	EPSD	TCGA;ICGC;COSMIC	8.808	Gain
CMGC_CDK_CDK5_CDK5_ST	O15169	AXIN1	Q00535	CDK5	T60	S57W	57	Missense	distal	-3	no	18.864	18.825	EPSD	TCGA	8.808	Down-regulation
CMGC_CDK_CDK5_CDK5_ST	O15169	AXIN1	Q00535	CDK5	T60	R63H	63	Missense	distal	3	no	18.864	17.844	EPSD	TCGA;ICGC;COSMIC	8.808	Down-regulation
CMGC_CDK_CDK5_CDK5_ST	O15169	AXIN1	Q00535	CDK5	T60	R62S	62	Missense	proximal	2	no	18.864	18.764	EPSD	TCGA;ICGC;COSMIC	8.808	Down-regulation
CMGC_CDK_CDK5_CDK5_ST	O15169	AXIN1	Q00535	CDK5	T60	R63L	63	Missense	distal	3	no	18.864	16.394	EPSD	TCGA;ICGC;COSMIC	8.808	Down-regulation
CMGC_CDK_CDK5_CDK5_ST	O15169	AXIN1	Q00535	CDK5	T60	P61L	61	Missense	proximal	1	no	18.864	6.914	EPSD	TCGA;ICGC;COSMIC	8.808	Loss
CMGC_CDK_CDK5_CDK5_ST	O15169	AXIN1	Q00535	CDK5	T60	T56A	56	Missense	distal	-4	no	18.864	18.464	EPSD	TCGA;ICGC;COSMIC	8.808	Down-regulation
CMGC_CDK_CDK5_CDK5_ST	O15169	AXIN1	Q00535	CDK5	S77	E73Q	73	Missense	distal	-4	no	17.831	17.988	EPSD	TCGA;ICGC;COSMIC	8.808	Up-regulation
CMGC_CDK_CDK5_CDK5_ST	O15169	AXIN1	Q00535	CDK5	S77	S77F	77	Missense	central	0	yes	17.831	0.000	EPSD	TCGA;ICGC;COSMIC	8.808	Loss
CMGC_CDK_CDK5_CDK5_ST	O15169	AXIN1	Q00535	CDK5	S77	P80T	80	Missense	distal	3	no	17.831	18.367	EPSD	TCGA;ICGC;COSMIC	8.808	Up-regulation
CMGC_CDK_CDK5_CDK5_ST	O15169	AXIN1	Q00535	CDK5	T79	E73Q	73	Missense	distal	-6	no	16.806	16.842	EPSD	TCGA;ICGC;COSMIC	8.808	Up-regulation
CMGC_CDK_CDK5_CDK5_ST	O15169	AXIN1	Q00535	CDK5	T79	S77F	77	Missense	proximal	-2	no	16.806	16.247	EPSD	TCGA;ICGC;COSMIC	8.808	Down-regulation
CMGC_CDK_CDK5_CDK5_ST	O15169	AXIN1	Q00535	CDK5	T79	P80T	80	Missense	proximal	1	no	16.806	6.319	EPSD	TCGA;ICGC;COSMIC	8.808	Loss
CMGC_CDK_CDK5_CDK5_ST	O15169	AXIN1	Q00535	CDK5	S283	S281F	281	Missense	proximal	-2	no	8.857	8.298	EPSD	TCGA;ICGC;COSMIC	8.808	Loss
CMGC_CDK_CDK5_CDK5_ST	O15169	AXIN1	Q00535	CDK5	T481	V478G	478	Missense	distal	-3	no	19.083	19.051	PhosphoSitePlus	TCGA;ICGC;COSMIC	8.808	Down-regulation
CMGC_CDK_CDK5_CDK5_ST	O15169	AXIN1	Q00535	CDK5	S542	S542R	542	Missense	central	0	yes	8.891	0.000	EPSD	TCGA;ICGC	8.808	Loss
CMGC_CDK_CDK5_CDK5_ST	O15169	AXIN1	Q00535	CDK5	S644	T649I	649	Missense	distal	5	no	9.494	9.405	EPSD	TCGA;ICGC;COSMIC	8.808	Down-regulation
CMGC_CDK_CDK5_CDK5_ST	P49768	PSEN1	Q00535	CDK5	S51	S51P	51	Missense	central	0	yes	9.934	0.000	EPSD	TCGA;ICGC;COSMIC	8.808	Loss
CMGC_CDK_CDK5_CDK5_ST	P49768	PSEN1	Q00535	CDK5	S319	E321K	321	Missense	proximal	2	no	9.168	9.418	EPSD	TCGA;COSMIC	8.808	Up-regulation
CMGC_CDK_CDK5_CDK5_ST	P49768	PSEN1	Q00535	CDK5	S319	S313F	313	Missense	distal	-6	no	9.168	8.995	EPSD	TCGA	8.808	Down-regulation
CMGC_CDK_CDK5_CDK5_ST	P49768	PSEN1	Q00535	CDK5	S324	E321K	321	Missense	distal	-3	no	9.836	9.908	EPSD	TCGA;COSMIC	8.808	Up-regulation
CMGC_CDK_CDK5_CDK5_ST	P49768	PSEN1	Q00535	CDK5	T354	P355A	355	Missense	proximal	1	no	17.332	6.305	PhosphoSitePlus	TCGA;COSMIC	8.808	Loss
CMGC_CDK_CDK5_CDK5_ST	P49768	PSEN1	Q00535	CDK5	S357	P355A	355	Missense	proximal	-2	no	10.082	9.705	EPSD	TCGA;COSMIC	8.808	Down-regulation
CMGC_CDK_CDK5_CDK5_ST	P49768	PSEN1	Q00535	CDK5	S357	E363Q	363	Missense	distal	6	no	10.082	10.088	EPSD	TCGA;COSMIC	8.808	Up-regulation
CMGC_CDK_CDK5_CDK5_ST	P02545	LMNA	Q00535	CDK5	S71	V69M	69	Missense	proximal	-2	no	8.851	8.459	EPSD	TCGA;ICGC;COSMIC	8.808	Loss
CMGC_CDK_CDK5_CDK5_ST	P02545	LMNA	Q00535	CDK5	S71	K78N	78	Missense	distal	7	no	8.851	8.839	EPSD	TCGA;ICGC;COSMIC	8.808	Down-regulation
CMGC_CDK_CDK5_CDK5_ST	P02545	LMNA	Q00535	CDK5	S295	E290K	290	Missense	distal	-5	no	9.880	10.170	EPSD	TCGA;COSMIC	8.808	Up-regulation
CMGC_CDK_CDK5_CDK5_ST	P02545	LMNA	Q00535	CDK5	S295	R296H	296	Missense	proximal	1	no	9.880	0.315	EPSD	TCGA;COSMIC	8.808	Loss
CMGC_CDK_CDK5_CDK5_ST	P02545	LMNA	Q00535	CDK5	S307	A304T	304	Missense	distal	-3	no	9.375	9.420	EPSD	TCGA;COSMIC	8.808	Up-regulation
CMGC_CDK_CDK5_CDK5_ST	P02545	LMNA	Q00535	CDK5	S390	R388C	388	Missense	proximal	-2	no	18.452	17.935	EPSD	TCGA;COSMIC	8.808	Down-regulation
CMGC_CDK_CDK5_CDK5_ST	P02545	LMNA	Q00535	CDK5	S390	S395L	395	Missense	distal	5	no	18.452	18.267	EPSD	TCGA;COSMIC	8.808	Down-regulation
CMGC_CDK_CDK5_CDK5_ST	P02545	LMNA	Q00535	CDK5	S392	R388C	388	Missense	distal	-4	no	18.400	17.837	PhosphoSitePlus	TCGA;COSMIC	8.808	Down-regulation
CMGC_CDK_CDK5_CDK5_ST	P02545	LMNA	Q00535	CDK5	S392	R399H	399	Missense	distal	7	no	18.400	18.393	PhosphoSitePlus	TCGA;COSMIC	8.808	Down-regulation
CMGC_CDK_CDK5_CDK5_ST	P02545	LMNA	Q00535	CDK5	S392	S395L	395	Missense	distal	3	no	18.400	17.348	PhosphoSitePlus	TCGA;COSMIC	8.808	Down-regulation
CMGC_CDK_CDK5_CDK5_ST	P02545	LMNA	Q00535	CDK5	S395	R388C	388	Missense	distal	-7	no	9.159	9.087	EPSD	TCGA;COSMIC	8.808	Down-regulation
CMGC_CDK_CDK5_CDK5_ST	P02545	LMNA	Q00535	CDK5	S395	R399H	399	Missense	distal	4	no	9.159	9.119	EPSD	TCGA;COSMIC	8.808	Down-regulation
CMGC_CDK_CDK5_CDK5_ST	P02545	LMNA	Q00535	CDK5	S395	R401C	401	Missense	distal	6	no	9.159	9.135	EPSD	TCGA;COSMIC	8.808	Down-regulation
CMGC_CDK_CDK5_CDK5_ST	P02545	LMNA	Q00535	CDK5	S395	S395L	395	Missense	central	0	yes	9.159	0.000	EPSD	TCGA;COSMIC	8.808	Loss
CMGC_CDK_CDK5_CDK5_ST	P02545	LMNA	Q00535	CDK5	S398	R399H	399	Missense	proximal	1	no	10.525	0.960	EPSD	TCGA;COSMIC	8.808	Loss
CMGC_CDK_CDK5_CDK5_ST	P02545	LMNA	Q00535	CDK5	S398	R401C	401	Missense	distal	3	no	10.525	8.229	EPSD	TCGA;COSMIC	8.808	Loss
CMGC_CDK_CDK5_CDK5_ST	P02545	LMNA	Q00535	CDK5	S398	S395L	395	Missense	distal	-3	no	10.525	10.470	EPSD	TCGA;COSMIC	8.808	Down-regulation
CMGC_CDK_CDK5_CDK5_ST	P02545	LMNA	Q00535	CDK5	T623	R624H	624	Missense	proximal	1	no	8.914	-0.651	EPSD	TCGA;COSMIC	8.808	Loss
CMGC_CDK_CDK5_CDK5_ST	P02545	LMNA	Q00535	CDK5	T655	N660S	660	Missense	distal	5	no	9.686	9.750	EPSD	TCGA;COSMIC	8.808	Up-regulation
CMGC_CDK_CDK5_CDK5_ST	P02545	LMNA	Q00535	CDK5	S657	N660S	660	Missense	distal	3	no	18.641	18.837	EPSD	TCGA;COSMIC	8.808	Up-regulation
CMGC_CDK_CDK5_CDK5_ST	Q9Y490	TLN1	Q00535	CDK5	T354	A361V	361	Missense	distal	7	no	9.636	9.644	EPSD	TCGA;ICGC;COSMIC	8.808	Up-regulation
CMGC_CDK_CDK5_CDK5_ST	Q9Y490	TLN1	Q00535	CDK5	S362	A361V	361	Missense	proximal	-1	no	17.595	17.599	EPSD	TCGA;ICGC;COSMIC	8.808	Up-regulation
CMGC_CDK_CDK5_CDK5_ST	Q9Y490	TLN1	Q00535	CDK5	S425	D422G	422	Missense	distal	-3	no	19.342	19.341	PhosphoSitePlus	TCGA;ICGC;COSMIC	8.808	Down-regulation
CMGC_CDK_CDK5_CDK5_ST	Q9Y490	TLN1	Q00535	CDK5	S425	S429L	429	Missense	distal	4	no	19.342	19.259	PhosphoSitePlus	TCGA;ICGC;COSMIC	8.808	Down-regulation
CMGC_CDK_CDK5_CDK5_ST	Q9Y490	TLN1	Q00535	CDK5	S425	E421Q	421	Missense	distal	-4	no	19.342	19.498	PhosphoSitePlus	TCGA;ICGC;COSMIC	8.808	Up-regulation
CMGC_CDK_CDK5_CDK5_ST	Q9Y490	TLN1	Q00535	CDK5	S425	T418N	418	Missense	distal	-7	no	19.342	19.330	PhosphoSitePlus	TCGA;ICGC;COSMIC	8.808	Down-regulation
CMGC_CDK_CDK5_CDK5_ST	Q9Y490	TLN1	Q00535	CDK5	S729	S728I	728	Missense	proximal	-1	no	16.449	16.446	EPSD	TCGA;ICGC;COSMIC	8.808	Down-regulation
CMGC_CDK_CDK5_CDK5_ST	Q9Y490	TLN1	Q00535	CDK5	S858	A859T	859	Missense	proximal	1	no	8.412	8.952	EPSD	TCGA	8.808	Gain
CMGC_CDK_CDK5_CDK5_ST	Q9Y490	TLN1	Q00535	CDK5	S940	A939P	939	Missense	proximal	-1	no	9.125	9.130	EPSD	TCGA;ICGC	8.808	Up-regulation
CMGC_CDK_CDK5_CDK5_ST	Q9Y490	TLN1	Q00535	CDK5	S940	G947S	947	Missense	distal	7	no	9.125	9.135	EPSD	TCGA;ICGC;COSMIC	8.808	Up-regulation
CMGC_CDK_CDK5_CDK5_ST	Q9Y490	TLN1	Q00535	CDK5	T941	A939P	939	Missense	proximal	-2	no	16.845	17.223	EPSD	TCGA;ICGC	8.808	Up-regulation
CMGC_CDK_CDK5_CDK5_ST	Q9Y490	TLN1	Q00535	CDK5	T941	G947S	947	Missense	distal	6	no	16.845	16.855	EPSD	TCGA;ICGC;COSMIC	8.808	Up-regulation
CMGC_CDK_CDK5_CDK5_ST	Q9Y490	TLN1	Q00535	CDK5	S1231	A1238G	1238	Missense	distal	7	no	9.006	9.007	EPSD	TCGA;ICGC;COSMIC	8.808	Up-regulation
CMGC_CDK_CDK5_CDK5_ST	Q9Y490	TLN1	Q00535	CDK5	S1231	P1229H	1229	Missense	proximal	-2	no	9.006	8.690	EPSD	TCGA;ICGC	8.808	Loss
CMGC_CDK_CDK5_CDK5_ST	Q9Y490	TLN1	Q00535	CDK5	S1303	R1298Q	1298	Missense	distal	-5	no	10.387	10.226	EPSD	TCGA;ICGC;COSMIC	8.808	Down-regulation
CMGC_CDK_CDK5_CDK5_ST	Q9Y490	TLN1	Q00535	CDK5	T1517	R1523C	1523	Missense	distal	6	no	9.320	9.296	EPSD	TCGA;ICGC;COSMIC	8.808	Down-regulation
CMGC_CDK_CDK5_CDK5_ST	Q9Y490	TLN1	Q00535	CDK5	T1517	T1520A	1520	Missense	distal	3	no	9.320	8.539	EPSD	TCGA;ICGC;COSMIC	8.808	Loss
CMGC_CDK_CDK5_CDK5_ST	Q9Y490	TLN1	Q00535	CDK5	T1517	K1522M	1522	Missense	distal	5	no	9.320	8.977	EPSD	TCGA;ICGC;COSMIC	8.808	Down-regulation
CMGC_CDK_CDK5_CDK5_ST	Q9Y490	TLN1	Q00535	CDK5	T1517	R1515G	1515	Missense	proximal	-2	no	9.320	8.910	EPSD	TCGA;ICGC;COSMIC	8.808	Down-regulation
CMGC_CDK_CDK5_CDK5_ST	Q9Y490	TLN1	Q00535	CDK5	T1517	P1519S	1519	Missense	proximal	2	no	9.320	9.302	EPSD	TCGA;ICGC;COSMIC	8.808	Down-regulation
CMGC_CDK_CDK5_CDK5_ST	Q9Y490	TLN1	Q00535	CDK5	T1517	R1515C	1515	Missense	proximal	-2	no	9.320	8.803	EPSD	TCGA;ICGC;COSMIC;GDSC;CCLE	8.808	Loss
CMGC_CDK_CDK5_CDK5_ST	Q9Y490	TLN1	Q00535	CDK5	T1517	R1510H	1510	Missense	distal	-7	no	9.320	9.288	EPSD	TCGA;ICGC;COSMIC;GDSC;CCLE	8.808	Down-regulation
CMGC_CDK_CDK5_CDK5_ST	Q9Y490	TLN1	Q00535	CDK5	S1589	R1593W	1593	Missense	distal	4	no	18.737	18.665	EPSD	TCGA;ICGC;COSMIC	8.808	Down-regulation
CMGC_CDK_CDK5_CDK5_ST	Q9Y490	TLN1	Q00535	CDK5	S1637	G1635A	1635	Missense	proximal	-2	no	9.394	9.481	EPSD	TCGA;ICGC;COSMIC	8.808	Up-regulation
CMGC_CDK_CDK5_CDK5_ST	Q9Y490	TLN1	Q00535	CDK5	S1694	R1690C	1690	Missense	distal	-4	no	9.218	8.655	EPSD	TCGA;COSMIC	8.808	Loss
CMGC_CDK_CDK5_CDK5_ST	Q9Y490	TLN1	Q00535	CDK5	S1694	S1694F	1694	Missense	central	0	yes	9.218	0.000	EPSD	TCGA;ICGC;COSMIC	8.808	Loss
CMGC_CDK_CDK5_CDK5_ST	Q9Y490	TLN1	Q00535	CDK5	S1940	C1939Y	1939	Missense	proximal	-1	no	15.916	15.917	EPSD	TCGA;COSMIC	8.808	Up-regulation
CMGC_CDK_CDK5_CDK5_ST	Q9Y490	TLN1	Q00535	CDK5	S2162	S2162F	2162	Missense	central	0	yes	17.127	0.000	EPSD	TCGA;COSMIC	8.808	Loss
CMGC_CDK_CDK5_CDK5_ST	Q9Y490	TLN1	Q00535	CDK5	S2162	A2167T	2167	Missense	distal	5	no	17.127	17.261	EPSD	TCGA	8.808	Up-regulation
CMGC_CDK_CDK5_CDK5_ST	Q9Y490	TLN1	Q00535	CDK5	S2162	F2160V	2160	Missense	proximal	-2	no	17.127	17.604	EPSD	TCGA;ICGC;COSMIC	8.808	Up-regulation
CMGC_CDK_CDK5_CDK5_ST	Q9Y490	TLN1	Q00535	CDK5	T2171	S2170F	2170	Missense	proximal	-1	no	16.394	16.385	EPSD	TCGA;COSMIC	8.808	Down-regulation
CMGC_CDK_CDK5_CDK5_ST	Q9Y490	TLN1	Q00535	CDK5	T2171	A2167T	2167	Missense	distal	-4	no	16.394	16.793	EPSD	TCGA	8.808	Up-regulation
CMGC_CDK_CDK5_CDK5_ST	Q9Y490	TLN1	Q00535	CDK5	S2262	P2261S	2261	Missense	proximal	-1	no	16.574	16.575	EPSD	TCGA;COSMIC	8.808	Up-regulation
CMGC_CDK_CDK5_CDK5_ST	O94916	NFAT5	Q00535	CDK5	T631	T631K	631	Missense	central	0	yes	9.031	0.000	EPSD	TCGA	8.808	Loss
CMGC_CDK_CDK5_CDK5_ST	Q15833	STXBP2	Q00535	CDK5	S21	R20W	20	Missense	proximal	-1	no	9.356	9.352	EPSD	TCGA;ICGC;COSMIC	8.808	Down-regulation
CMGC_CDK_CDK5_CDK5_ST	Q15833	STXBP2	Q00535	CDK5	S21	E27K	27	Missense	distal	6	no	9.356	9.375	EPSD	TCGA;ICGC;COSMIC	8.808	Up-regulation
CMGC_CDK_CDK5_CDK5_ST	Q15833	STXBP2	Q00535	CDK5	S78	K82T	82	Missense	distal	4	no	16.781	16.714	EPSD	TCGA;ICGC;COSMIC	8.808	Down-regulation
CMGC_CDK_CDK5_CDK5_ST	Q15833	STXBP2	Q00535	CDK5	T94	I88T	88	Missense	distal	-6	no	16.636	16.681	EPSD	TCGA;ICGC;COSMIC	8.808	Up-regulation
CMGC_CDK_CDK5_CDK5_ST	Q15833	STXBP2	Q00535	CDK5	T94	G93R	93	Missense	proximal	-1	no	16.636	16.640	EPSD	TCGA;COSMIC	8.808	Up-regulation
CMGC_CDK_CDK5_CDK5_ST	Q15833	STXBP2	Q00535	CDK5	T94	F91V	91	Missense	distal	-3	no	16.636	16.704	EPSD	TCGA	8.808	Up-regulation
CMGC_CDK_CDK5_CDK5_ST	Q15833	STXBP2	Q00535	CDK5	T216	D215Y	215	Missense	proximal	-1	no	15.645	15.643	EPSD	TCGA;COSMIC	8.808	Down-regulation
CMGC_CDK_CDK5_CDK5_ST	Q15833	STXBP2	Q00535	CDK5	S458	E461D	461	Missense	distal	3	no	8.894	8.828	EPSD	TCGA;COSMIC	8.808	Down-regulation
CMGC_CDK_CDK5_CDK5_ST	Q15833	STXBP2	Q00535	CDK5	S458	E461K	461	Missense	distal	3	no	8.894	11.180	EPSD	TCGA;COSMIC	8.808	Up-regulation
CMGC_CDK_CDK5_CDK5_ST	Q15833	STXBP2	Q00535	CDK5	S458	R465H	465	Missense	distal	7	no	8.894	8.887	EPSD	TCGA;COSMIC	8.808	Down-regulation
CMGC_CDK_CDK5_CDK5_ST	Q15833	STXBP2	Q00535	CDK5	S458	R465C	465	Missense	distal	7	no	8.894	8.877	EPSD	TCGA;COSMIC;GDSC	8.808	Down-regulation
CMGC_CDK_CDK5_CDK5_ST	Q15833	STXBP2	Q00535	CDK5	S473	Q471L	471	Missense	proximal	-2	no	9.688	9.465	EPSD	TCGA;COSMIC	8.808	Down-regulation
CMGC_CDK_CDK5_CDK5_ST	Q15833	STXBP2	Q00535	CDK5	S473	P477L	477	Missense	distal	4	no	9.688	9.607	EPSD	TCGA;COSMIC	8.808	Down-regulation
CMGC_CDK_CDK5_CDK5_ST	Q15833	STXBP2	Q00535	CDK5	S473	R474H	474	Missense	proximal	1	no	9.688	0.123	EPSD	TCGA	8.808	Loss
CMGC_CDK_CDK5_CDK5_ST	Q15833	STXBP2	Q00535	CDK5	T572	S567C	567	Missense	distal	-5	no	19.849	19.575	PhosphoSitePlus	TCGA;COSMIC	8.808	Down-regulation
CMGC_CDK_CDK5_CDK5_ST	P08670	VIM	Q00535	CDK5	S9	S8L	8	Missense	proximal	-1	no	8.979	8.973	EPSD	TCGA;ICGC;COSMIC	8.808	Down-regulation
CMGC_CDK_CDK5_CDK5_ST	P08670	VIM	Q00535	CDK5	S9	F15L	15	Missense	distal	6	no	8.979	8.985	EPSD	TCGA;ICGC;COSMIC	8.808	Up-regulation
CMGC_CDK_CDK5_CDK5_ST	P08670	VIM	Q00535	CDK5	S9	F15V	15	Missense	distal	6	no	8.979	8.996	EPSD	TCGA;ICGC	8.808	Up-regulation
CMGC_CDK_CDK5_CDK5_ST	P08670	VIM	Q00535	CDK5	T20	F15V	15	Missense	distal	-5	no	8.655	8.928	EPSD	TCGA;ICGC	8.808	Gain
CMGC_CDK_CDK5_CDK5_ST	P08670	VIM	Q00535	CDK5	S22	S22I	22	Missense	central	0	yes	9.998	0.000	EPSD	TCGA;ICGC;COSMIC	8.808	Loss
CMGC_CDK_CDK5_CDK5_ST	P08670	VIM	Q00535	CDK5	S22	F15L	15	Missense	distal	-7	no	9.998	10.026	EPSD	TCGA;ICGC;COSMIC	8.808	Up-regulation
CMGC_CDK_CDK5_CDK5_ST	P08670	VIM	Q00535	CDK5	S22	F15V	15	Missense	distal	-7	no	9.998	10.064	EPSD	TCGA;ICGC	8.808	Up-regulation
CMGC_CDK_CDK5_CDK5_ST	P08670	VIM	Q00535	CDK5	S56	R50H	50	Missense	distal	-6	no	16.965	16.899	PhosphoSitePlus	TCGA;ICGC;COSMIC	8.808	Down-regulation
CMGC_CDK_CDK5_CDK5_ST	P08670	VIM	Q00535	CDK5	S56	P57L	57	Missense	proximal	1	no	16.965	5.015	PhosphoSitePlus	TCGA;ICGC;COSMIC;CCLE	8.808	Loss
CMGC_CDK_CDK5_CDK5_ST	P08670	VIM	Q00535	CDK5	S56	P57R	57	Missense	proximal	1	no	16.965	8.018	PhosphoSitePlus	TCGA;ICGC;COSMIC	8.808	Loss
CMGC_CDK_CDK5_CDK5_ST	P08670	VIM	Q00535	CDK5	S420	L421P	421	Missense	proximal	1	no	4.776	16.725	EPSD	TCGA;ICGC;COSMIC	8.808	Gain
CMGC_CDK_CDK5_CDK5_ST	P08670	VIM	Q00535	CDK5	T449	R450T	450	Missense	proximal	1	no	9.448	7.908	EPSD	TCGA;ICGC;COSMIC	8.808	Loss
CMGC_CDK_CDK5_CDK5_ST	P08670	VIM	Q00535	CDK5	S459	E457K	457	Missense	proximal	-2	no	9.622	10.035	EPSD	TCGA;ICGC;COSMIC;CCLE	8.808	Up-regulation
CAMK_CAMK1_PNCK_ST	P08238	HSP90AB1	Q6P2M8	PNCK	S58	D52N	52	Missense	distal	-6	no	2.362	2.285	EPSD	TCGA;ICGC;COSMIC	1.882	Down-regulation
CAMK_CAMK1_PNCK_ST	P08238	HSP90AB1	Q6P2M8	PNCK	S58	Y56C	56	Missense	proximal	-2	no	2.362	2.356	EPSD	TCGA;ICGC;COSMIC	1.882	Down-regulation
CAMK_CAMK1_PNCK_ST	P08238	HSP90AB1	Q6P2M8	PNCK	T89	T83A	83	Missense	distal	-6	no	7.022	6.853	PhosphoSitePlus	TCGA	1.882	Down-regulation
CAMK_CAMK1_PNCK_ST	P08238	HSP90AB1	Q6P2M8	PNCK	T89	G90D	90	Missense	proximal	1	no	7.022	6.827	PhosphoSitePlus	TCGA;ICGC	1.882	Down-regulation
CAMK_CAMK1_PNCK_ST	P08238	HSP90AB1	Q6P2M8	PNCK	T89	R82C	82	Missense	distal	-7	no	7.022	7.061	PhosphoSitePlus	TCGA;ICGC;COSMIC	1.882	Up-regulation
CAMK_CAMK1_PNCK_ST	P08238	HSP90AB1	Q6P2M8	PNCK	T89	G92D	92	Missense	distal	3	no	7.022	7.407	PhosphoSitePlus	TCGA;ICGC;COSMIC;GDSC;CCLE	1.882	Up-regulation
CAMK_CAMK1_PNCK_ST	P08238	HSP90AB1	Q6P2M8	PNCK	T89	T94S	94	Missense	distal	5	no	7.022	6.500	PhosphoSitePlus	TCGA;ICGC	1.882	Down-regulation
CAMK_CAMK1_PNCK_ST	P08238	HSP90AB1	Q6P2M8	PNCK	T94	G90D	90	Missense	distal	-4	no	2.016	1.905	EPSD	TCGA;ICGC	1.882	Down-regulation
CAMK_CAMK1_PNCK_ST	P08238	HSP90AB1	Q6P2M8	PNCK	T94	G92D	92	Missense	proximal	-2	no	2.016	2.078	EPSD	TCGA;ICGC;COSMIC;GDSC;CCLE	1.882	Up-regulation
CAMK_CAMK1_PNCK_ST	P08238	HSP90AB1	Q6P2M8	PNCK	S124	G127V	127	Missense	distal	3	no	2.320	2.644	EPSD	TCGA;ICGC;COSMIC	1.882	Up-regulation
CAMK_CAMK1_PNCK_ST	P08238	HSP90AB1	Q6P2M8	PNCK	S255	E251K	251	Missense	distal	-4	no	2.222	1.823	EPSD	TCGA;ICGC;COSMIC;GDSC;CCLE	1.882	Loss
CAMK_CAMK1_PNCK_ST	P08238	HSP90AB1	Q6P2M8	PNCK	S255	I250V	250	Missense	distal	-5	no	2.222	1.854	EPSD	TCGA;ICGC;COSMIC	1.882	Loss
CAMK_CAMK1_PNCK_ST	P08238	HSP90AB1	Q6P2M8	PNCK	S255	D256V	256	Missense	proximal	1	no	2.222	2.441	EPSD	TCGA;ICGC;COSMIC	1.882	Up-regulation
CAMK_CAMK1_PNCK_ST	P08238	HSP90AB1	Q6P2M8	PNCK	S255	D256A	256	Missense	proximal	1	no	2.222	2.412	EPSD	TCGA;ICGC;COSMIC	1.882	Up-regulation
CAMK_CAMK1_PNCK_ST	P08238	HSP90AB1	Q6P2M8	PNCK	S261	K263E	263	Missense	proximal	2	no	2.394	2.359	EPSD	TCGA;ICGC;COSMIC	1.882	Down-regulation
CAMK_CAMK1_PNCK_ST	P08238	HSP90AB1	Q6P2M8	PNCK	S261	D256V	256	Missense	distal	-5	no	2.394	2.697	EPSD	TCGA;ICGC;COSMIC	1.882	Up-regulation
CAMK_CAMK1_PNCK_ST	P08238	HSP90AB1	Q6P2M8	PNCK	S261	D256A	256	Missense	distal	-5	no	2.394	2.953	EPSD	TCGA;ICGC;COSMIC	1.882	Up-regulation
CAMK_CAMK1_PNCK_ST	P08238	HSP90AB1	Q6P2M8	PNCK	S261	K265N	265	Missense	distal	4	no	2.394	2.250	EPSD	TCGA;ICGC;COSMIC	1.882	Down-regulation
CAMK_CAMK1_PNCK_ST	P08238	HSP90AB1	Q6P2M8	PNCK	S261	K267N	267	Missense	distal	6	no	2.394	2.399	EPSD	TCGA;ICGC;COSMIC	1.882	Up-regulation
CAMK_CAMK1_PNCK_ST	P08238	HSP90AB1	Q6P2M8	PNCK	S322	E328K	328	Missense	distal	6	no	1.718	1.886	EPSD	TCGA;ICGC	1.882	Gain
CAMK_CAMK1_PNCK_ST	P08238	HSP90AB1	Q6P2M8	PNCK	S365	M363V	363	Missense	proximal	-2	no	1.942	2.046	EPSD	TCGA;ICGC;COSMIC	1.882	Up-regulation
CAMK_CAMK1_PNCK_ST	P08238	HSP90AB1	Q6P2M8	PNCK	S365	R359H	359	Missense	distal	-6	no	1.942	1.956	EPSD	TCGA;ICGC;COSMIC	1.882	Up-regulation
CAMK_CAMK1_PNCK_ST	P08238	HSP90AB1	Q6P2M8	PNCK	S398	R392Q	392	Missense	distal	-6	no	2.677	2.695	EPSD	TCGA;ICGC;COSMIC	1.882	Up-regulation
CAMK_CAMK1_PNCK_ST	P08238	HSP90AB1	Q6P2M8	PNCK	S398	R405H	405	Missense	distal	7	no	2.677	3.003	EPSD	TCGA;ICGC;COSMIC;GDSC;CCLE	1.882	Up-regulation
CAMK_CAMK1_PNCK_ST	P08238	HSP90AB1	Q6P2M8	PNCK	S434	K427N	427	Missense	distal	-7	no	1.911	2.016	EPSD	TCGA;ICGC;COSMIC	1.882	Up-regulation
CAMK_CAMK1_PNCK_ST	P08238	HSP90AB1	Q6P2M8	PNCK	T616	R612Q	612	Missense	distal	-4	no	5.610	5.411	EPSD	TCGA;ICGC;COSMIC	1.882	Down-regulation
CAMK_CAMK1_PNCK_ST	O43432	EIF4G3	Q6P2M8	PNCK	T1266	V1263A	1263	Missense	distal	-3	no	2.253	1.751	EPSD	TCGA;COSMIC	1.882	Loss
CAMK_PKD_PRKD2_ST	P50552	VASP	Q9BZL6	PRKD2	S157	R154C	154	Missense	distal	-3	no	3.561	2.713	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	1.791	Down-regulation
CAMK_PKD_PRKD2_ST	P50552	VASP	Q9BZL6	PRKD2	S239	E242D	242	Missense	distal	3	no	3.894	3.899	PhosphoSitePlus;EPSD	TCGA;ICGC;COSMIC	1.791	Up-regulation
CAMK_PKD_PRKD2_ST	P50552	VASP	Q9BZL6	PRKD2	S322	R319W	319	Missense	distal	-3	no	3.733	2.850	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	1.791	Down-regulation
CAMK_PKD_PRKD2_ST	P50552	VASP	Q9BZL6	PRKD2	S322	P318S	318	Missense	distal	-4	no	3.733	3.711	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	1.791	Down-regulation
CAMK_PKD_PRKD2_ST	P50552	VASP	Q9BZL6	PRKD2	S323	E330K	330	Missense	distal	7	no	1.795	1.789	EPSD	TCGA;ICGC;COSMIC	1.791	Loss
CAMK_PKD_PRKD2_ST	P50552	VASP	Q9BZL6	PRKD2	S323	R319W	319	Missense	distal	-4	no	1.795	1.794	EPSD	TCGA;ICGC;COSMIC	1.791	Down-regulation
CAMK_PKD_PRKD2_ST	P50552	VASP	Q9BZL6	PRKD2	S323	P318S	318	Missense	distal	-5	no	1.795	2.066	EPSD	TCGA;ICGC;COSMIC	1.791	Up-regulation
CAMK_PKD_PRKD2_ST	P50552	VASP	Q9BZL6	PRKD2	S324	E330K	330	Missense	distal	6	no	1.765	1.791	EPSD	TCGA;ICGC;COSMIC	1.791	Gain
CAMK_PKD_PRKD2_ST	P50552	VASP	Q9BZL6	PRKD2	S324	R319W	319	Missense	distal	-5	no	1.765	2.079	EPSD	TCGA;ICGC;COSMIC	1.791	Gain
CAMK_PKD_PRKD2_ST	P50552	VASP	Q9BZL6	PRKD2	S339	T335A	335	Missense	distal	-4	no	1.797	1.791	EPSD	TCGA;ICGC;COSMIC	1.791	Down-regulation
CAMK_PKD_PRKD2_ST	Q8WYL5	SSH1	Q9BZL6	PRKD2	S400	R399H	399	Missense	proximal	-1	no	1.957	2.033	EPSD	TCGA;ICGC;COSMIC	1.791	Up-regulation
CAMK_PKD_PRKD2_ST	Q8WYL5	SSH1	Q9BZL6	PRKD2	S400	V397L	397	Missense	distal	-3	no	1.957	1.517	EPSD	TCGA;ICGC;COSMIC	1.791	Loss
CAMK_PKD_PRKD2_ST	Q8WYL5	SSH1	Q9BZL6	PRKD2	S400	S400L	400	Missense	central	0	yes	1.957	0.000	EPSD	TCGA;ICGC;COSMIC	1.791	Loss
CAMK_PKD_PRKD2_ST	Q8WYL5	SSH1	Q9BZL6	PRKD2	S402	R399H	399	Missense	distal	-3	no	1.829	0.677	EPSD	TCGA;ICGC;COSMIC	1.791	Loss
CAMK_PKD_PRKD2_ST	Q8WYL5	SSH1	Q9BZL6	PRKD2	S402	V397L	397	Missense	distal	-5	no	1.829	2.108	EPSD	TCGA;ICGC;COSMIC	1.791	Up-regulation
CAMK_PKD_PRKD2_ST	Q8WYL5	SSH1	Q9BZL6	PRKD2	S402	S400L	400	Missense	proximal	-2	no	1.829	1.663	EPSD	TCGA;ICGC;COSMIC	1.791	Loss
CAMK_PKD_PRKD2_ST	Q8WYL5	SSH1	Q9BZL6	PRKD2	S428	I429V	429	Missense	proximal	1	no	2.263	2.234	EPSD	TCGA	1.791	Down-regulation
CAMK_PKD_PRKD2_ST	Q8WYL5	SSH1	Q9BZL6	PRKD2	S428	R427C	427	Missense	proximal	-1	no	2.263	2.314	EPSD	TCGA;ICGC;COSMIC	1.791	Up-regulation
CAMK_PKD_PRKD2_ST	Q8WYL5	SSH1	Q9BZL6	PRKD2	S441	Y443C	443	Missense	proximal	2	no	1.910	1.913	EPSD	TCGA;ICGC;COSMIC	1.791	Up-regulation
CAMK_PKD_PRKD2_ST	Q8WYL5	SSH1	Q9BZL6	PRKD2	T462	P469L	469	Missense	distal	7	no	2.221	2.225	EPSD	TCGA;ICGC;COSMIC	1.791	Up-regulation
CAMK_PKD_PRKD2_ST	Q8WYL5	SSH1	Q9BZL6	PRKD2	S515	F511L	511	Missense	distal	-4	no	2.479	2.469	EPSD	TCGA;ICGC	1.791	Down-regulation
CAMK_PKD_PRKD2_ST	Q8WYL5	SSH1	Q9BZL6	PRKD2	S515	P508T	508	Missense	distal	-7	no	2.479	2.534	EPSD	TCGA;ICGC;COSMIC	1.791	Up-regulation
CAMK_PKD_PRKD2_ST	Q8WYL5	SSH1	Q9BZL6	PRKD2	S583	G579S	579	Missense	distal	-4	no	2.440	2.417	EPSD	TCGA;ICGC;COSMIC	1.791	Down-regulation
CAMK_PKD_PRKD2_ST	Q8WYL5	SSH1	Q9BZL6	PRKD2	S583	P577S	577	Missense	distal	-6	no	2.440	2.424	EPSD	TCGA;ICGC;COSMIC	1.791	Down-regulation
CAMK_PKD_PRKD2_ST	Q8WYL5	SSH1	Q9BZL6	PRKD2	S696	H693Y	693	Missense	distal	-3	no	1.548	1.793	EPSD	TCGA;ICGC;COSMIC	1.791	Gain
CAMK_PKD_PRKD2_ST	Q8WYL5	SSH1	Q9BZL6	PRKD2	S777	K774R	774	Missense	distal	-3	no	1.621	2.253	EPSD	TCGA;ICGC;COSMIC	1.791	Gain
CAMK_PKD_PRKD2_ST	Q8WYL5	SSH1	Q9BZL6	PRKD2	S778	K774R	774	Missense	distal	-4	no	2.239	2.258	EPSD	TCGA;ICGC;COSMIC	1.791	Up-regulation
CAMK_PKD_PRKD2_ST	Q8WYL5	SSH1	Q9BZL6	PRKD2	S778	S777L	777	Missense	proximal	-1	no	2.239	2.232	EPSD	TCGA;ICGC;COSMIC	1.791	Down-regulation
CAMK_PKD_PRKD2_ST	Q8WYL5	SSH1	Q9BZL6	PRKD2	S834	P841S	841	Missense	distal	7	no	2.520	2.461	EPSD	TCGA;ICGC;COSMIC	1.791	Down-regulation
CAMK_PKD_PRKD2_ST	Q8WYL5	SSH1	Q9BZL6	PRKD2	S834	R831W	831	Missense	distal	-3	no	2.520	1.638	EPSD	TCGA;ICGC;COSMIC	1.791	Loss
CAMK_PKD_PRKD2_ST	Q8WYL5	SSH1	Q9BZL6	PRKD2	S894	K896N	896	Missense	proximal	2	no	2.185	2.176	EPSD	TCGA;ICGC;COSMIC	1.791	Down-regulation
CAMK_PKD_PRKD2_ST	Q8WYL5	SSH1	Q9BZL6	PRKD2	S894	P900L	900	Missense	distal	6	no	2.185	2.096	EPSD	TCGA;ICGC;COSMIC	1.791	Down-regulation
CAMK_PKD_PRKD2_ST	Q8WYL5	SSH1	Q9BZL6	PRKD2	S912	H907L	907	Missense	distal	-5	no	1.191	1.817	EPSD	TCGA;ICGC	1.791	Gain
CAMK_PKD_PRKD2_ST	Q8WYL5	SSH1	Q9BZL6	PRKD2	S937	R934Q	934	Missense	distal	-3	no	4.154	3.080	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	1.791	Down-regulation
CAMK_PKD_PRKD2_ST	Q8WYL5	SSH1	Q9BZL6	PRKD2	S937	R934W	934	Missense	distal	-3	no	4.154	3.271	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	1.791	Down-regulation
CAMK_PKD_PRKD2_ST	Q8WYL5	SSH1	Q9BZL6	PRKD2	S937	S940N	940	Missense	distal	3	no	4.154	4.175	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	1.791	Up-regulation
CAMK_PKD_PRKD2_ST	Q8WYL5	SSH1	Q9BZL6	PRKD2	S984	T989M	989	Missense	distal	5	no	1.911	1.920	EPSD	TCGA;ICGC;COSMIC	1.791	Up-regulation
CAMK_PKD_PRKD2_ST	Q8WYL5	SSH1	Q9BZL6	PRKD2	T989	T989M	989	Missense	central	0	yes	1.881	0.000	EPSD	TCGA;ICGC;COSMIC	1.791	Loss
CAMK_PKD_PRKD2_ST	Q9UQL6	HDAC5	Q9BZL6	PRKD2	T546	E551D	551	Missense	distal	5	no	2.278	2.257	EPSD	TCGA;ICGC;COSMIC	1.791	Down-regulation
CAMK_PKD_PRKD2_ST	Q13563	PKD2	Q9BZL6	PRKD2	S80	P78L	78	Missense	proximal	-2	no	2.104	2.023	EPSD	TCGA;ICGC;COSMIC	1.791	Down-regulation
CAMK_PKD_PRKD2_ST	Q13563	PKD2	Q9BZL6	PRKD2	S801	R798H	798	Missense	distal	-3	no	3.671	2.519	PhosphoSitePlus	TCGA;COSMIC	1.791	Down-regulation
CAMK_PKD_PRKD2_ST	Q13563	PKD2	Q9BZL6	PRKD2	S801	S795Y	795	Missense	distal	-6	no	3.671	3.691	PhosphoSitePlus	TCGA;COSMIC	1.791	Up-regulation
CAMK_PKD_PRKD2_ST	Q13563	PKD2	Q9BZL6	PRKD2	S801	R803Q	803	Missense	proximal	2	no	3.671	3.691	PhosphoSitePlus	TCGA;COSMIC	1.791	Up-regulation
CAMK_PKD_PRKD2_ST	Q13563	PKD2	Q9BZL6	PRKD2	S802	R803Q	803	Missense	proximal	1	no	1.609	1.833	EPSD	TCGA;COSMIC	1.791	Gain
CAMK_PKD_PRKD2_ST	Q13563	PKD2	Q9BZL6	PRKD2	S808	S812F	812	Missense	distal	4	no	1.478	1.820	EPSD	TCGA;COSMIC	1.791	Gain
CAMK_PKD_PRKD2_ST	Q13563	PKD2	Q9BZL6	PRKD2	S808	R803Q	803	Missense	distal	-5	no	1.478	1.850	EPSD	TCGA;COSMIC	1.791	Gain
CAMK_PKD_PRKD2_ST	Q13563	PKD2	Q9BZL6	PRKD2	S829	G833D	833	Missense	distal	4	no	2.515	2.419	EPSD	TCGA;COSMIC	1.791	Down-regulation
CAMK_PKD_PRKD2_ST	Q13563	PKD2	Q9BZL6	PRKD2	S948	G954S	954	Missense	distal	6	no	2.528	2.759	EPSD	TCGA	1.791	Up-regulation
CAMK_PKD_PRKD2_ST	Q13563	PKD2	Q9BZL6	PRKD2	S948	S949F	949	Missense	proximal	1	no	2.528	2.209	EPSD	TCGA;COSMIC	1.791	Down-regulation
CAMK_PKD_PRKD2_ST	Q7KZI7	MARK2	Q9BZL6	PRKD2	S274	R268C	268	Missense	distal	-6	no	1.792	1.783	EPSD	TCGA;ICGC;COSMIC	1.791	Loss
CAMK_PKD_PRKD2_ST	Q7KZI7	MARK2	Q9BZL6	PRKD2	S274	Y272C	272	Missense	proximal	-2	no	1.792	1.828	EPSD	TCGA;ICGC	1.791	Up-regulation
CAMK_PKD_PRKD2_ST	Q7KZI7	MARK2	Q9BZL6	PRKD2	S366	G370D	370	Missense	distal	4	no	2.095	1.999	EPSD	TCGA;COSMIC	1.791	Down-regulation
CAMK_PKD_PRKD2_ST	Q7KZI7	MARK2	Q9BZL6	PRKD2	S366	L361M	361	Missense	distal	-5	no	2.095	1.640	EPSD	TCGA;COSMIC	1.791	Loss
CAMK_PKD_PRKD2_ST	Q7KZI7	MARK2	Q9BZL6	PRKD2	T374	G370D	370	Missense	distal	-4	no	1.804	1.800	EPSD	TCGA;COSMIC	1.791	Down-regulation
CAMK_PKD_PRKD2_ST	Q7KZI7	MARK2	Q9BZL6	PRKD2	S400	N402S	402	Missense	proximal	2	no	3.643	3.651	PhosphoSitePlus	TCGA;ICGC;COSMIC	1.791	Up-regulation
CAMK_PKD_PRKD2_ST	Q7KZI7	MARK2	Q9BZL6	PRKD2	S400	V399M	399	Missense	proximal	-1	no	3.643	3.588	PhosphoSitePlus	TCGA;ICGC;COSMIC	1.791	Down-regulation
CAMK_PKD_PRKD2_ST	Q7KZI7	MARK2	Q9BZL6	PRKD2	S409	N402S	402	Missense	distal	-7	no	1.952	2.039	EPSD	TCGA;ICGC;COSMIC	1.791	Up-regulation
CAMK_PKD_PRKD2_ST	Q7KZI7	MARK2	Q9BZL6	PRKD2	S422	T427A	427	Missense	distal	5	no	1.866	1.879	EPSD	TCGA;COSMIC	1.791	Up-regulation
CAMK_PKD_PRKD2_ST	Q7KZI7	MARK2	Q9BZL6	PRKD2	S493	G495S	495	Missense	proximal	2	no	2.084	2.097	EPSD	TCGA;COSMIC	1.791	Up-regulation
CAMK_PKD_PRKD2_ST	Q7KZI7	MARK2	Q9BZL6	PRKD2	S493	Q500H	500	Missense	distal	7	no	2.084	2.104	EPSD	TCGA;COSMIC	1.791	Up-regulation
CAMK_PKD_PRKD2_ST	Q7KZI7	MARK2	Q9BZL6	PRKD2	S493	P487S	487	Missense	distal	-6	no	2.084	2.068	EPSD	TCGA;COSMIC	1.791	Down-regulation
CAMK_PKD_PRKD2_ST	Q7KZI7	MARK2	Q9BZL6	PRKD2	S493	R491W	491	Missense	proximal	-2	no	2.084	1.874	EPSD	TCGA;COSMIC	1.791	Down-regulation
CAMK_PKD_PRKD2_ST	Q7KZI7	MARK2	Q9BZL6	PRKD2	S498	G495S	495	Missense	distal	-3	no	2.485	2.595	EPSD	TCGA;COSMIC	1.791	Up-regulation
CAMK_PKD_PRKD2_ST	Q7KZI7	MARK2	Q9BZL6	PRKD2	S498	Q500H	500	Missense	proximal	2	no	2.485	2.475	EPSD	TCGA;COSMIC	1.791	Down-regulation
CAMK_PKD_PRKD2_ST	Q7KZI7	MARK2	Q9BZL6	PRKD2	S498	R491W	491	Missense	distal	-7	no	2.485	2.459	EPSD	TCGA;COSMIC	1.791	Down-regulation
CAMK_PKD_PRKD2_ST	Q7KZI7	MARK2	Q9BZL6	PRKD2	S511	S514Y	514	Missense	distal	3	no	1.823	1.853	EPSD	TCGA;COSMIC	1.791	Up-regulation
CAMK_PKD_PRKD2_ST	Q7KZI7	MARK2	Q9BZL6	PRKD2	S511	P509L	509	Missense	proximal	-2	no	1.823	1.742	EPSD	TCGA;COSMIC	1.791	Loss
CAMK_PKD_PRKD2_ST	Q7KZI7	MARK2	Q9BZL6	PRKD2	S511	T515M	515	Missense	distal	4	no	1.823	1.784	EPSD	TCGA;COSMIC	1.791	Loss
CAMK_PKD_PRKD2_ST	Q7KZI7	MARK2	Q9BZL6	PRKD2	S523	R528C	528	Missense	distal	5	no	1.789	1.820	EPSD	TCGA;COSMIC	1.791	Gain
CAMK_PKD_PRKD2_ST	Q7KZI7	MARK2	Q9BZL6	PRKD2	S537	N541Y	541	Missense	distal	4	no	1.963	2.059	EPSD	TCGA;COSMIC	1.791	Up-regulation
CAMK_PKD_PRKD2_ST	Q7KZI7	MARK2	Q9BZL6	PRKD2	T560	R557Q	557	Missense	distal	-3	no	2.202	1.128	EPSD	TCGA;COSMIC	1.791	Loss
CAMK_PKD_PRKD2_ST	Q7KZI7	MARK2	Q9BZL6	PRKD2	T560	P566S	566	Missense	distal	6	no	2.202	2.355	EPSD	TCGA;COSMIC	1.791	Up-regulation
CAMK_PKD_PRKD2_ST	Q7KZI7	MARK2	Q9BZL6	PRKD2	S577	R584Q	584	Missense	distal	7	no	1.986	1.980	EPSD	TCGA;COSMIC	1.791	Down-regulation
CAMK_PKD_PRKD2_ST	Q7KZI7	MARK2	Q9BZL6	PRKD2	S577	P582S	582	Missense	distal	5	no	1.986	2.006	EPSD	TCGA;COSMIC	1.791	Up-regulation
CAMK_PKD_PRKD2_ST	Q7KZI7	MARK2	Q9BZL6	PRKD2	S577	A572T	572	Missense	distal	-5	no	1.986	1.881	EPSD	TCGA;COSMIC	1.791	Down-regulation
CAMK_PKD_PRKD2_ST	Q7KZI7	MARK2	Q9BZL6	PRKD2	S592	H598N	598	Missense	distal	6	no	2.192	2.229	EPSD	TCGA	1.791	Up-regulation
CAMK_PKD_PRKD2_ST	Q7KZI7	MARK2	Q9BZL6	PRKD2	S592	T596P	596	Missense	distal	4	no	2.192	2.354	EPSD	TCGA;COSMIC	1.791	Up-regulation
CAMK_PKD_PRKD2_ST	Q7KZI7	MARK2	Q9BZL6	PRKD2	S592	R594Q	594	Missense	proximal	2	no	2.192	2.212	EPSD	TCGA;COSMIC	1.791	Up-regulation
CAMK_PKD_PRKD2_ST	Q7KZI7	MARK2	Q9BZL6	PRKD2	S593	R594Q	594	Missense	proximal	1	no	1.620	1.843	EPSD	TCGA;COSMIC	1.791	Gain
CAMK_PKD_PRKD2_ST	Q7KZI7	MARK2	Q9BZL6	PRKD2	S648	R644H	644	Missense	distal	-4	no	1.913	1.907	EPSD	TCGA;COSMIC	1.791	Down-regulation
CAMK_PKD_PRKD2_ST	Q7KZI7	MARK2	Q9BZL6	PRKD2	S698	T702M	702	Missense	distal	4	no	1.986	1.946	EPSD	TCGA;COSMIC	1.791	Down-regulation
CAMK_PKD_PRKD2_ST	Q7KZI7	MARK2	Q9BZL6	PRKD2	S698	R694H	694	Missense	distal	-4	no	1.986	1.980	EPSD	TCGA	1.791	Down-regulation
CAMK_PKD_PRKD2_ST	Q01105	SET	Q9BZL6	PRKD2	S63	V69L	69	Missense	distal	6	no	1.965	1.879	EPSD	TCGA;ICGC;COSMIC	1.791	Down-regulation
CAMK_PKD_PRKD2_ST	Q01105	SET	Q9BZL6	PRKD2	S63	E65K	65	Missense	proximal	2	no	1.965	1.981	EPSD	TCGA;ICGC;COSMIC	1.791	Up-regulation
CAMK_PKD_PRKD2_ST	Q01105	SET	Q9BZL6	PRKD2	S63	E65D	65	Missense	proximal	2	no	1.965	1.969	EPSD	TCGA;ICGC;COSMIC	1.791	Up-regulation
CAMK_PKD_PRKD2_ST	Q01105	SET	Q9BZL6	PRKD2	S175	E170K	170	Missense	distal	-5	no	1.701	2.158	EPSD	TCGA;COSMIC	1.791	Gain
CAMK_PKD_PRKD2_ST	Q01105	SET	Q9BZL6	PRKD2	S184	T186M	186	Missense	proximal	2	no	3.687	3.688	EPSD	TCGA;ICGC;COSMIC	1.791	Up-regulation
CAMK_PKD_PRKD2_ST	Q01105	SET	Q9BZL6	PRKD2	S184	S191N	191	Missense	distal	7	no	3.687	3.714	EPSD	TCGA;COSMIC	1.791	Up-regulation
CAMK_PKD_PRKD2_ST	Q01105	SET	Q9BZL6	PRKD2	S184	S183L	183	Missense	proximal	-1	no	3.687	3.680	EPSD	TCGA;ICGC;COSMIC	1.791	Down-regulation
CAMK_PKD_PRKD2_ST	Q01105	SET	Q9BZL6	PRKD2	S184	N188D	188	Missense	distal	4	no	3.687	3.824	EPSD	TCGA;COSMIC	1.791	Up-regulation
CAMK_PKD_PRKD2_ST	Q01105	SET	Q9BZL6	PRKD2	S184	T180M	180	Missense	distal	-4	no	3.687	3.688	EPSD	TCGA;COSMIC	1.791	Up-regulation
CAMK_PKD_PRKD2_ST	Q01105	SET	Q9BZL6	PRKD2	S184	R182C	182	Missense	proximal	-2	no	3.687	3.509	EPSD	TCGA	1.791	Down-regulation
CAMK_PKD_PRKD2_ST	Q01105	SET	Q9BZL6	PRKD2	S201	D208Y	208	Missense	distal	7	no	2.143	2.145	EPSD	TCGA;COSMIC	1.791	Up-regulation
CAMK_PKD_PRKD2_ST	Q01105	SET	Q9BZL6	PRKD2	S201	E200D	200	Missense	proximal	-1	no	2.143	2.141	EPSD	TCGA;ICGC	1.791	Down-regulation
CAMK_PKD_PRKD2_ST	Q9BZL6	PRKD2	Q9BZL6	PRKD2	S197	R195C	195	Missense	proximal	-2	no	2.449	2.270	EPSD	TCGA;COSMIC	1.791	Down-regulation
CAMK_PKD_PRKD2_ST	Q9BZL6	PRKD2	Q9BZL6	PRKD2	S197	K193E	193	Missense	distal	-4	no	2.449	2.459	EPSD	TCGA;COSMIC	1.791	Up-regulation
CAMK_PKD_PRKD2_ST	Q9BZL6	PRKD2	Q9BZL6	PRKD2	S197	S203T	203	Missense	distal	6	no	2.449	2.338	EPSD	TCGA;COSMIC	1.791	Down-regulation
CAMK_PKD_PRKD2_ST	Q9BZL6	PRKD2	Q9BZL6	PRKD2	S197	R195H	195	Missense	proximal	-2	no	2.449	2.220	EPSD	TCGA;COSMIC	1.791	Down-regulation
CAMK_PKD_PRKD2_ST	Q9BZL6	PRKD2	Q9BZL6	PRKD2	S197	R192H	192	Missense	distal	-5	no	2.449	2.641	EPSD	TCGA	1.791	Up-regulation
CAMK_PKD_PRKD2_ST	Q9BZL6	PRKD2	Q9BZL6	PRKD2	S197	R194W	194	Missense	distal	-3	no	2.449	1.566	EPSD	TCGA	1.791	Loss
CAMK_PKD_PRKD2_ST	Q9BZL6	PRKD2	Q9BZL6	PRKD2	S197	T199M	199	Missense	proximal	2	no	2.449	2.450	EPSD	TCGA	1.791	Up-regulation
CAMK_PKD_PRKD2_ST	Q9BZL6	PRKD2	Q9BZL6	PRKD2	S206	S206L	206	Missense	central	0	yes	1.819	0.000	EPSD	TCGA;COSMIC	1.791	Loss
CAMK_PKD_PRKD2_ST	Q9BZL6	PRKD2	Q9BZL6	PRKD2	S206	S203T	203	Missense	distal	-3	no	1.819	2.009	EPSD	TCGA;COSMIC	1.791	Up-regulation
CAMK_PKD_PRKD2_ST	Q9BZL6	PRKD2	Q9BZL6	PRKD2	S206	T211N	211	Missense	distal	5	no	1.819	1.821	EPSD	TCGA;COSMIC	1.791	Up-regulation
CAMK_PKD_PRKD2_ST	Q9BZL6	PRKD2	Q9BZL6	PRKD2	S206	T199M	199	Missense	distal	-7	no	1.819	1.812	EPSD	TCGA	1.791	Down-regulation
CAMK_PKD_PRKD2_ST	Q9BZL6	PRKD2	Q9BZL6	PRKD2	S223	R224H	224	Missense	proximal	1	no	2.366	2.546	EPSD	TCGA;COSMIC	1.791	Up-regulation
CAMK_PKD_PRKD2_ST	Q9BZL6	PRKD2	Q9BZL6	PRKD2	S223	E228K	228	Missense	distal	5	no	2.366	2.371	EPSD	TCGA;COSMIC;CCLE	1.791	Up-regulation
CAMK_PKD_PRKD2_ST	Q9BZL6	PRKD2	Q9BZL6	PRKD2	T227	R224H	224	Missense	distal	-3	no	2.443	1.291	EPSD	TCGA;COSMIC	1.791	Loss
CAMK_PKD_PRKD2_ST	Q9BZL6	PRKD2	Q9BZL6	PRKD2	T227	E228K	228	Missense	proximal	1	no	2.443	2.483	EPSD	TCGA;COSMIC;CCLE	1.791	Up-regulation
CAMK_PKD_PRKD2_ST	Q9BZL6	PRKD2	Q9BZL6	PRKD2	S374	P380L	380	Missense	distal	6	no	1.876	1.788	EPSD	TCGA;COSMIC	1.791	Loss
CAMK_PKD_PRKD2_ST	Q9BZL6	PRKD2	Q9BZL6	PRKD2	T392	R393W	393	Missense	proximal	1	no	1.991	2.045	EPSD	TCGA;COSMIC	1.791	Up-regulation
CAMK_PKD_PRKD2_ST	Q9BZL6	PRKD2	Q9BZL6	PRKD2	S396	R393W	393	Missense	distal	-3	no	1.906	1.024	EPSD	TCGA;COSMIC	1.791	Loss
CAMK_PKD_PRKD2_ST	Q9BZL6	PRKD2	Q9BZL6	PRKD2	S529	S529F	529	Missense	central	0	yes	2.224	0.000	EPSD	TCGA;COSMIC	1.791	Loss
CAMK_PKD_PRKD2_ST	Q9BZL6	PRKD2	Q9BZL6	PRKD2	S710	A716T	716	Missense	distal	6	no	3.496	3.480	EPSD	TCGA;COSMIC	1.791	Down-regulation
CAMK_PKD_PRKD2_ST	Q9BZL6	PRKD2	Q9BZL6	PRKD2	S710	R709H	709	Missense	proximal	-1	no	3.496	3.572	EPSD	TCGA;COSMIC	1.791	Up-regulation
CAMK_PKD_PRKD2_ST	Q9BZL6	PRKD2	Q9BZL6	PRKD2	S710	S706L	706	Missense	distal	-4	no	3.496	3.516	EPSD	TCGA;COSMIC	1.791	Up-regulation
CAMK_PKD_PRKD2_ST	Q9BZL6	PRKD2	Q9BZL6	PRKD2	S710	P715S	715	Missense	distal	5	no	3.496	3.516	EPSD	TCGA;COSMIC	1.791	Up-regulation
CAMK_PKD_PRKD2_ST	Q9BZL6	PRKD2	Q9BZL6	PRKD2	S797	R793H	793	Missense	distal	-4	no	2.159	2.153	EPSD	TCGA;COSMIC	1.791	Down-regulation
CAMK_PKD_PRKD2_ST	Q9BZL6	PRKD2	Q9BZL6	PRKD2	S797	K794T	794	Missense	distal	-3	no	2.159	1.998	EPSD	TCGA	1.791	Down-regulation
CAMK_PKD_PRKD2_ST	Q9BZL6	PRKD2	Q9BZL6	PRKD2	S797	S801F	801	Missense	distal	4	no	2.159	2.501	EPSD	TCGA;COSMIC	1.791	Up-regulation
CAMK_PKD_PRKD2_ST	Q9BZL6	PRKD2	Q9BZL6	PRKD2	S797	R795H	795	Missense	proximal	-2	no	2.159	1.930	EPSD	TCGA;COSMIC	1.791	Down-regulation
CAMK_PKD_PRKD2_ST	Q9BZL6	PRKD2	Q9BZL6	PRKD2	S797	S803G	803	Missense	distal	6	no	2.159	1.927	EPSD	TCGA;COSMIC	1.791	Down-regulation
CAMK_PKD_PRKD2_ST	Q9BZL6	PRKD2	Q9BZL6	PRKD2	S876	R874H	874	Missense	proximal	-2	no	2.335	2.107	PhosphoSitePlus	TCGA;COSMIC	1.791	Down-regulation
CAMK_PKD_PRKD2_ST	Q9BZL6	PRKD2	Q9BZL6	PRKD2	S876	R874C	874	Missense	proximal	-2	no	2.335	2.157	PhosphoSitePlus	TCGA;COSMIC;GDSC;CCLE	1.791	Down-regulation
CAMK_PKD_PRKD2_ST	P16144	ITGB4	Q9BZL6	PRKD2	T210	E215Q	215	Missense	distal	5	no	1.994	2.012	EPSD	TCGA;ICGC;COSMIC	1.791	Up-regulation
CAMK_PKD_PRKD2_ST	P16144	ITGB4	Q9BZL6	PRKD2	T210	R217Q	217	Missense	distal	7	no	1.994	1.988	EPSD	TCGA;ICGC;COSMIC	1.791	Down-regulation
CAMK_PKD_PRKD2_ST	P16144	ITGB4	Q9BZL6	PRKD2	S368	E361K	361	Missense	distal	-7	no	2.612	2.625	EPSD	TCGA;ICGC;COSMIC	1.791	Up-regulation
CAMK_PKD_PRKD2_ST	P16144	ITGB4	Q9BZL6	PRKD2	S368	A362D	362	Missense	distal	-6	no	2.612	2.624	EPSD	TCGA;ICGC;COSMIC	1.791	Up-regulation
CAMK_PKD_PRKD2_ST	P16144	ITGB4	Q9BZL6	PRKD2	S368	E361D	361	Missense	distal	-7	no	2.612	2.566	EPSD	TCGA;ICGC	1.791	Down-regulation
CAMK_PKD_PRKD2_ST	P16144	ITGB4	Q9BZL6	PRKD2	S368	S368F	368	Missense	central	0	yes	2.612	0.000	EPSD	TCGA;ICGC;COSMIC	1.791	Loss
CAMK_PKD_PRKD2_ST	P16144	ITGB4	Q9BZL6	PRKD2	S368	R365Q	365	Missense	distal	-3	no	2.612	1.538	EPSD	TCGA;COSMIC	1.791	Loss
CAMK_PKD_PRKD2_ST	P16144	ITGB4	Q9BZL6	PRKD2	S368	R373W	373	Missense	distal	5	no	2.612	2.632	EPSD	TCGA;ICGC;COSMIC	1.791	Up-regulation
CAMK_PKD_PRKD2_ST	P16144	ITGB4	Q9BZL6	PRKD2	T829	R823C	823	Missense	distal	-6	no	2.144	2.135	EPSD	TCGA;ICGC	1.791	Down-regulation
CAMK_PKD_PRKD2_ST	P16144	ITGB4	Q9BZL6	PRKD2	T982	R989T	989	Missense	distal	7	no	1.935	1.934	EPSD	TCGA;ICGC;COSMIC	1.791	Down-regulation
CAMK_PKD_PRKD2_ST	P16144	ITGB4	Q9BZL6	PRKD2	T982	A988D	988	Missense	distal	6	no	1.935	1.877	EPSD	TCGA;ICGC;COSMIC	1.791	Down-regulation
CAMK_PKD_PRKD2_ST	P16144	ITGB4	Q9BZL6	PRKD2	T982	G975D	975	Missense	distal	-7	no	1.935	1.953	EPSD	TCGA;ICGC;COSMIC	1.791	Up-regulation
CAMK_PKD_PRKD2_ST	P16144	ITGB4	Q9BZL6	PRKD2	T982	R977L	977	Missense	distal	-5	no	1.935	2.754	EPSD	TCGA;ICGC;COSMIC	1.791	Up-regulation
CAMK_PKD_PRKD2_ST	P16144	ITGB4	Q9BZL6	PRKD2	S1084	R1077H	1077	Missense	distal	-7	no	2.192	2.177	EPSD	TCGA;ICGC;COSMIC	1.791	Down-regulation
CAMK_PKD_PRKD2_ST	P16144	ITGB4	Q9BZL6	PRKD2	S1084	V1081I	1081	Missense	distal	-3	no	2.192	2.167	EPSD	TCGA;ICGC;COSMIC	1.791	Down-regulation
CAMK_PKD_PRKD2_ST	P16144	ITGB4	Q9BZL6	PRKD2	S1084	A1090V	1090	Missense	distal	6	no	2.192	2.131	EPSD	TCGA;ICGC;COSMIC	1.791	Down-regulation
CAMK_PKD_PRKD2_ST	P16144	ITGB4	Q9BZL6	PRKD2	S1084	G1089W	1089	Missense	distal	5	no	2.192	2.199	EPSD	TCGA;ICGC;COSMIC	1.791	Up-regulation
CAMK_PKD_PRKD2_ST	P16144	ITGB4	Q9BZL6	PRKD2	T1113	M1116K	1116	Missense	distal	3	no	2.284	2.278	EPSD	TCGA;ICGC;COSMIC	1.791	Down-regulation
CAMK_PKD_PRKD2_ST	P16144	ITGB4	Q9BZL6	PRKD2	S1118	M1116K	1116	Missense	proximal	-2	no	2.001	2.051	EPSD	TCGA;ICGC;COSMIC	1.791	Up-regulation
CAMK_PKD_PRKD2_ST	P16144	ITGB4	Q9BZL6	PRKD2	S1119	M1116K	1116	Missense	distal	-3	no	1.925	2.194	EPSD	TCGA;ICGC;COSMIC	1.791	Up-regulation
CAMK_PKD_PRKD2_ST	P16144	ITGB4	Q9BZL6	PRKD2	S1345	G1340E	1340	Missense	distal	-5	no	1.897	1.664	EPSD	TCGA;ICGC;COSMIC	1.791	Loss
CAMK_PKD_PRKD2_ST	P16144	ITGB4	Q9BZL6	PRKD2	S1345	D1351N	1351	Missense	distal	6	no	1.897	1.938	EPSD	TCGA;ICGC	1.791	Up-regulation
CAMK_PKD_PRKD2_ST	P16144	ITGB4	Q9BZL6	PRKD2	S1345	M1348I	1348	Missense	distal	3	no	1.897	1.906	EPSD	TCGA;ICGC;COSMIC	1.791	Up-regulation
CAMK_PKD_PRKD2_ST	P16144	ITGB4	Q9BZL6	PRKD2	S1345	E1341G	1341	Missense	distal	-4	no	1.897	1.903	EPSD	TCGA;ICGC;COSMIC	1.791	Up-regulation
CAMK_PKD_PRKD2_ST	P16144	ITGB4	Q9BZL6	PRKD2	S1358	D1351N	1351	Missense	distal	-7	no	3.017	3.013	EPSD	TCGA;ICGC	1.791	Down-regulation
CAMK_PKD_PRKD2_ST	P16144	ITGB4	Q9BZL6	PRKD2	S1358	R1355C	1355	Missense	distal	-3	no	3.017	2.169	EPSD	TCGA;ICGC;COSMIC	1.791	Down-regulation
CAMK_PKD_PRKD2_ST	P16144	ITGB4	Q9BZL6	PRKD2	S1358	G1359S	1359	Missense	proximal	1	no	3.017	3.337	EPSD	TCGA;ICGC;COSMIC	1.791	Up-regulation
CAMK_PKD_PRKD2_ST	P16144	ITGB4	Q9BZL6	PRKD2	S1358	S1358L	1358	Missense	central	0	yes	3.017	0.000	EPSD	TCGA;ICGC;COSMIC	1.791	Loss
CAMK_PKD_PRKD2_ST	P16144	ITGB4	Q9BZL6	PRKD2	S1358	R1362K	1362	Missense	distal	4	no	3.017	2.895	EPSD	TCGA;ICGC;COSMIC	1.791	Down-regulation
CAMK_PKD_PRKD2_ST	P16144	ITGB4	Q9BZL6	PRKD2	T1463	Y1469H	1469	Missense	distal	6	no	2.253	2.279	EPSD	TCGA;COSMIC	1.791	Up-regulation
CAMK_PKD_PRKD2_ST	P16144	ITGB4	Q9BZL6	PRKD2	T1463	M1461T	1461	Missense	proximal	-2	no	2.253	2.276	EPSD	TCGA;COSMIC	1.791	Up-regulation
CAMK_PKD_PRKD2_ST	P16144	ITGB4	Q9BZL6	PRKD2	T1463	Y1469F	1469	Missense	distal	6	no	2.253	2.208	EPSD	TCGA;COSMIC	1.791	Down-regulation
CAMK_PKD_PRKD2_ST	P16144	ITGB4	Q9BZL6	PRKD2	S1511	S1517Y	1517	Missense	distal	6	no	3.025	2.852	EPSD	TCGA;COSMIC	1.791	Down-regulation
CAMK_PKD_PRKD2_ST	P16144	ITGB4	Q9BZL6	PRKD2	S1511	D1509Y	1509	Missense	proximal	-2	no	3.025	2.986	EPSD	TCGA;COSMIC	1.791	Down-regulation
CAMK_PKD_PRKD2_ST	P16144	ITGB4	Q9BZL6	PRKD2	S1604	R1599H	1599	Missense	distal	-5	no	2.353	2.546	EPSD	TCGA;COSMIC	1.791	Up-regulation
CAMK_PKD_PRKD2_ST	P16144	ITGB4	Q9BZL6	PRKD2	S1604	G1609S	1609	Missense	distal	5	no	2.353	2.390	EPSD	TCGA;COSMIC	1.791	Up-regulation
CAMK_PKD_PRKD2_ST	P16144	ITGB4	Q9BZL6	PRKD2	S1736	I1734V	1734	Missense	proximal	-2	no	1.879	1.852	PhosphoSitePlus	TCGA;COSMIC	1.791	Down-regulation
CAMK_PKD_PRKD2_ST	P16144	ITGB4	Q9BZL6	PRKD2	S1736	G1730D	1730	Missense	distal	-6	no	1.879	1.885	PhosphoSitePlus	TCGA;COSMIC	1.791	Up-regulation
CAMK_PKD_PRKD2_ST	P16144	ITGB4	Q9BZL6	PRKD2	S1736	P1743L	1743	Missense	distal	7	no	1.879	1.883	PhosphoSitePlus	TCGA	1.791	Up-regulation
CAMK_PKD_PRKD2_ST	P16144	ITGB4	Q9BZL6	PRKD2	T1797	T1804A	1804	Missense	distal	7	no	2.609	2.596	EPSD	TCGA	1.791	Down-regulation
CAMK_PKD_PRKD2_ST	P16144	ITGB4	Q9BZL6	PRKD2	T1806	T1813S	1813	Missense	distal	7	no	2.846	2.816	EPSD	TCGA;COSMIC	1.791	Down-regulation
CAMK_PKD_PRKD2_ST	P16144	ITGB4	Q9BZL6	PRKD2	T1806	T1810A	1810	Missense	distal	4	no	2.846	2.733	EPSD	TCGA;COSMIC	1.791	Down-regulation
CAMK_PKD_PRKD2_ST	P16144	ITGB4	Q9BZL6	PRKD2	T1806	T1804A	1804	Missense	proximal	-2	no	2.846	2.837	EPSD	TCGA	1.791	Down-regulation
CAMK_PKD_PRKD2_ST	Q13671	RIN1	Q9BZL6	PRKD2	S255	R248C	248	Missense	distal	-7	no	2.005	1.986	EPSD	TCGA;ICGC;COSMIC;GDSC;CCLE	1.791	Down-regulation
CAMK_PKD_PRKD2_ST	Q13671	RIN1	Q9BZL6	PRKD2	S255	V249M	249	Missense	distal	-6	no	2.005	1.998	EPSD	TCGA;ICGC;COSMIC	1.791	Down-regulation
CAMK_PKD_PRKD2_ST	Q13671	RIN1	Q9BZL6	PRKD2	S255	P259L	259	Missense	distal	4	no	2.005	1.856	EPSD	TCGA;ICGC;COSMIC	1.791	Down-regulation
CAMK_PKD_PRKD2_ST	Q13671	RIN1	Q9BZL6	PRKD2	S255	S254F	254	Missense	proximal	-1	no	2.005	1.855	EPSD	TCGA;ICGC;COSMIC	1.791	Down-regulation
CAMK_PKD_PRKD2_ST	Q13671	RIN1	Q9BZL6	PRKD2	S291	L287I	287	Missense	distal	-4	no	2.183	2.176	EPSD	TCGA;ICGC	1.791	Down-regulation
CAMK_PKD_PRKD2_ST	Q13671	RIN1	Q9BZL6	PRKD2	S292	L287I	287	Missense	distal	-5	no	3.868	3.724	PhosphoSitePlus	TCGA;ICGC	1.791	Down-regulation
CAMK_PKD_PRKD2_ST	Q13671	RIN1	Q9BZL6	PRKD2	S337	S333N	333	Missense	distal	-4	no	1.969	1.987	EPSD	TCGA;ICGC;COSMIC	1.791	Up-regulation
CAMK_PKD_PRKD2_ST	Q13671	RIN1	Q9BZL6	PRKD2	S337	R344Q	344	Missense	distal	7	no	1.969	1.964	EPSD	TCGA;ICGC;COSMIC	1.791	Down-regulation
CAMK_PKD_PRKD2_ST	Q13671	RIN1	Q9BZL6	PRKD2	S351	R344Q	344	Missense	distal	-7	no	2.587	2.611	EPSD	TCGA;ICGC;COSMIC	1.791	Up-regulation
CAMK_PKD_PRKD2_ST	Q13671	RIN1	Q9BZL6	PRKD2	S424	E420K	420	Missense	distal	-4	no	1.945	1.935	EPSD	TCGA;ICGC;COSMIC	1.791	Down-regulation
CAMK_PKD_PRKD2_ST	Q13671	RIN1	Q9BZL6	PRKD2	S611	R616C	616	Missense	distal	5	no	2.887	2.918	EPSD	TCGA;ICGC;COSMIC	1.791	Up-regulation
CAMK_PKD_PRKD2_ST	Q99828	CIB1	Q9BZL6	PRKD2	S78	R72Q	72	Missense	distal	-6	no	3.471	3.454	PhosphoSitePlus	TCGA;ICGC;COSMIC	1.791	Down-regulation
CAMK_CAMK2_CAMK2B_ST	O14490	DLGAP1	Q13554	CAMK2B	S346	I348M	348	Missense	proximal	2	no	125.035	129.084	EPSD	TCGA;COSMIC	127.946	Gain
CAMK_CAMK2_CAMK2B_ST	O14490	DLGAP1	Q13554	CAMK2B	S375	R373K	373	Missense	proximal	-2	no	140.853	146.294	EPSD	TCGA;COSMIC	127.946	Up-regulation
CAMK_CAMK2_CAMK2B_ST	O14490	DLGAP1	Q13554	CAMK2B	S375	R372Q	372	Missense	distal	-3	no	140.853	111.514	EPSD	TCGA;COSMIC	127.946	Loss
CAMK_CAMK2_CAMK2B_ST	O14490	DLGAP1	Q13554	CAMK2B	S375	Q381E	381	Missense	distal	6	no	140.853	140.335	EPSD	TCGA;COSMIC	127.946	Down-regulation
CAMK_CAMK2_CAMK2B_ST	O14490	DLGAP1	Q13554	CAMK2B	S383	T385A	385	Missense	proximal	2	no	129.041	129.362	EPSD	TCGA;COSMIC	127.946	Up-regulation
CAMK_CAMK2_CAMK2B_ST	O14490	DLGAP1	Q13554	CAMK2B	S383	Q381E	381	Missense	proximal	-2	no	129.041	123.077	EPSD	TCGA;COSMIC	127.946	Loss
CAMK_CAMK2_CAMK2B_ST	O14490	DLGAP1	Q13554	CAMK2B	S503	D506N	506	Missense	distal	3	no	137.801	137.285	EPSD	TCGA;COSMIC	127.946	Down-regulation
CAMK_CAMK2_CAMK2B_ST	O14490	DLGAP1	Q13554	CAMK2B	S503	S510P	510	Missense	distal	7	no	137.801	142.758	EPSD	TCGA;COSMIC	127.946	Up-regulation
CAMK_CAMK2_CAMK2B_ST	O14490	DLGAP1	Q13554	CAMK2B	S510	D506N	506	Missense	distal	-4	no	114.158	129.567	EPSD	TCGA;COSMIC	127.946	Gain
CAMK_CAMK2_CAMK2B_ST	O14490	DLGAP1	Q13554	CAMK2B	S510	L511M	511	Missense	proximal	1	no	114.158	128.374	EPSD	TCGA;COSMIC	127.946	Gain
CAMK_CAMK2_CAMK2B_ST	O14490	DLGAP1	Q13554	CAMK2B	S562	Q567H	567	Missense	distal	5	no	128.558	128.887	EPSD	TCGA;COSMIC	127.946	Up-regulation
CAMK_CAMK2_CAMK2B_ST	O14490	DLGAP1	Q13554	CAMK2B	S589	S587R	587	Missense	proximal	-2	no	129.687	133.201	EPSD	TCGA;COSMIC	127.946	Up-regulation
CAMK_CAMK2_CAMK2B_ST	O14490	DLGAP1	Q13554	CAMK2B	S589	L593M	593	Missense	distal	4	no	129.687	129.436	EPSD	TCGA	127.946	Down-regulation
CAMK_CAMK2_CAMK2B_ST	O14490	DLGAP1	Q13554	CAMK2B	S589	Q583K	583	Missense	distal	-6	no	129.687	130.268	EPSD	TCGA;COSMIC	127.946	Up-regulation
CAMK_CAMK2_CAMK2B_ST	O14490	DLGAP1	Q13554	CAMK2B	S589	S587G	587	Missense	proximal	-2	no	129.687	134.433	EPSD	TCGA;COSMIC	127.946	Up-regulation
CAMK_CAMK2_CAMK2B_ST	O14490	DLGAP1	Q13554	CAMK2B	S589	S584Y	584	Missense	distal	-5	no	129.687	122.195	EPSD	TCGA;COSMIC	127.946	Loss
CAMK_CAMK2_CAMK2B_ST	O14490	DLGAP1	Q13554	CAMK2B	S592	S587R	587	Missense	distal	-5	no	132.614	131.974	EPSD	TCGA;COSMIC	127.946	Down-regulation
CAMK_CAMK2_CAMK2B_ST	O14490	DLGAP1	Q13554	CAMK2B	S592	L593M	593	Missense	proximal	1	no	132.614	146.830	EPSD	TCGA	127.946	Up-regulation
CAMK_CAMK2_CAMK2B_ST	O14490	DLGAP1	Q13554	CAMK2B	S592	S587G	587	Missense	distal	-5	no	132.614	131.544	EPSD	TCGA;COSMIC	127.946	Down-regulation
CAMK_CAMK2_CAMK2B_ST	O14490	DLGAP1	Q13554	CAMK2B	S595	A602T	602	Missense	distal	7	no	145.617	142.400	EPSD	TCGA;COSMIC;GDSC;CCLE	127.946	Down-regulation
CAMK_CAMK2_CAMK2B_ST	O14490	DLGAP1	Q13554	CAMK2B	S595	L593M	593	Missense	proximal	-2	no	145.617	147.179	EPSD	TCGA	127.946	Up-regulation
CAMK_CAMK2_CAMK2B_ST	O14490	DLGAP1	Q13554	CAMK2B	S651	I652F	652	Missense	proximal	1	no	141.216	127.900	EPSD	TCGA;COSMIC	127.946	Loss
CAMK_CAMK2_CAMK2B_ST	O14490	DLGAP1	Q13554	CAMK2B	S695	R692Q	692	Missense	distal	-3	no	139.671	110.331	EPSD	TCGA;COSMIC	127.946	Loss
CAMK_CAMK2_CAMK2B_ST	Q16625	OCLN	Q13554	CAMK2B	T305	D307N	307	Missense	proximal	2	no	136.260	137.930	EPSD	TCGA;ICGC;COSMIC	127.946	Up-regulation
CAMK_CAMK2_CAMK2B_ST	Q13555	CAMK2G	Q13554	CAMK2B	T254	I255V	255	Missense	proximal	1	no	144.247	135.542	EPSD	TCGA;ICGC	127.946	Down-regulation
CAMK_CAMK2_CAMK2B_ST	Q13555	CAMK2G	Q13554	CAMK2B	S280	R275Q	275	Missense	distal	-5	no	132.658	128.649	EPSD	TCGA;ICGC	127.946	Down-regulation
CAMK_CAMK2_CAMK2B_ST	Q13555	CAMK2G	Q13554	CAMK2B	T287	F294L	294	Missense	distal	7	no	161.152	158.359	PhosphoSitePlus	TCGA;COSMIC;CCLE	127.946	Down-regulation
CAMK_CAMK2_CAMK2B_ST	Q13555	CAMK2G	Q13554	CAMK2B	T287	R292H	292	Missense	distal	5	no	161.152	160.626	PhosphoSitePlus	TCGA;ICGC	127.946	Down-regulation
CAMK_CAMK2_CAMK2B_ST	Q13555	CAMK2G	Q13554	CAMK2B	S315	A317V	317	Missense	proximal	2	no	158.111	149.644	EPSD	TCGA;ICGC	127.946	Down-regulation
CAMK_CAMK2_CAMK2B_ST	Q13555	CAMK2G	Q13554	CAMK2B	S319	S325L	325	Missense	distal	6	no	148.629	147.304	EPSD	TCGA;ICGC;COSMIC	127.946	Down-regulation
CAMK_CAMK2_CAMK2B_ST	Q13555	CAMK2G	Q13554	CAMK2B	S319	A317V	317	Missense	proximal	-2	no	148.629	139.834	EPSD	TCGA;ICGC	127.946	Down-regulation
CAMK_CAMK2_CAMK2B_ST	Q13555	CAMK2G	Q13554	CAMK2B	S325	S325L	325	Missense	central	0	yes	158.691	0.000	EPSD	TCGA;ICGC;COSMIC	127.946	Loss
CAMK_CAMK2_CAMK2B_ST	P16949	STMN1	Q13554	CAMK2B	S46	P39S	39	Missense	distal	-7	no	132.998	134.486	EPSD	TCGA;ICGC;COSMIC	127.946	Up-regulation
CAMK_CAMK2_CAMK2B_ST	P16949	STMN1	Q13554	CAMK2B	S46	L47R	47	Missense	proximal	1	no	132.998	118.716	EPSD	TCGA;ICGC;COSMIC	127.946	Loss
CAMK_CAMK2_CAMK2B_ST	P16949	STMN1	Q13554	CAMK2B	S63	E58D	58	Missense	distal	-5	no	130.393	136.945	EPSD	TCGA;ICGC;COSMIC	127.946	Up-regulation
CAMK_CAMK2_CAMK2B_ST	P16949	STMN1	Q13554	CAMK2B	S63	A66G	66	Missense	distal	3	no	130.393	129.533	EPSD	TCGA;ICGC;COSMIC	127.946	Down-regulation
CAMK_CAMK2_CAMK2B_ST	P16949	STMN1	Q13554	CAMK2B	S63	R61H	61	Missense	proximal	-2	no	130.393	120.703	EPSD	TCGA;ICGC;COSMIC	127.946	Loss
CAMK_CAMK2_CAMK2B_ST	P16949	STMN1	Q13554	CAMK2B	S63	S63P	63	Missense	central	0	yes	130.393	0.000	EPSD	TCGA;ICGC;COSMIC	127.946	Loss
STE_STE20_PAKB_PAK5_ST	P15976	GATA1	Q9P286	PAK5	S107	E114K	114	Missense	distal	7	no	4.412	4.515	EPSD	TCGA;ICGC;COSMIC	3.202	Up-regulation
STE_STE20_PAKB_PAK5_ST	P15976	GATA1	Q9P286	PAK5	S107	T112N	112	Missense	distal	5	no	4.412	4.429	EPSD	TCGA;ICGC;COSMIC	3.202	Up-regulation
STE_STE20_PAKB_PAK5_ST	P15976	GATA1	Q9P286	PAK5	S187	S187F	187	Missense	central	0	yes	7.306	0.000	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	3.202	Loss
STE_STE20_PAKB_PAK5_ST	P15976	GATA1	Q9P286	PAK5	S187	R191C	191	Missense	distal	4	no	7.306	7.349	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	3.202	Up-regulation
STE_STE20_PAKB_PAK5_ST	P15976	GATA1	Q9P286	PAK5	T304	R307L	307	Missense	distal	3	no	3.260	3.213	EPSD	TCGA;ICGC;COSMIC	3.202	Down-regulation
STE_STE20_PAKB_PAK5_ST	P15976	GATA1	Q9P286	PAK5	T304	R307H	307	Missense	distal	3	no	3.260	3.237	EPSD	TCGA;ICGC;CCLE	3.202	Down-regulation
STE_STE20_PAKB_PAK5_ST	P15923	TCF3	Q9P286	PAK5	S55	E51D	51	Missense	distal	-4	no	4.552	4.513	EPSD	TCGA	3.202	Down-regulation
STE_STE20_PAKB_PAK5_ST	P15923	TCF3	Q9P286	PAK5	S110	R105Q	105	Missense	distal	-5	no	4.236	4.245	EPSD	TCGA;ICGC;COSMIC	3.202	Up-regulation
STE_STE20_PAKB_PAK5_ST	P15923	TCF3	Q9P286	PAK5	S157	R160I	160	Missense	distal	3	no	3.421	3.390	EPSD	TCGA;ICGC;COSMIC	3.202	Down-regulation
STE_STE20_PAKB_PAK5_ST	P15923	TCF3	Q9P286	PAK5	S157	G164D	164	Missense	distal	7	no	3.421	3.298	EPSD	TCGA;ICGC;COSMIC	3.202	Down-regulation
STE_STE20_PAKB_PAK5_ST	P15923	TCF3	Q9P286	PAK5	S157	R159W	159	Missense	proximal	2	no	3.421	3.455	EPSD	TCGA;ICGC;COSMIC	3.202	Up-regulation
STE_STE20_PAKB_PAK5_ST	P15923	TCF3	Q9P286	PAK5	S157	A162T	162	Missense	distal	5	no	3.421	3.408	EPSD	TCGA;ICGC	3.202	Down-regulation
STE_STE20_PAKB_PAK5_ST	P15923	TCF3	Q9P286	PAK5	S157	S157Y	157	Missense	central	0	yes	3.421	0.000	EPSD	TCGA;ICGC;COSMIC	3.202	Loss
STE_STE20_PAKB_PAK5_ST	P15923	TCF3	Q9P286	PAK5	T198	P201S	201	Missense	distal	3	no	4.908	4.998	EPSD	TCGA;ICGC;COSMIC	3.202	Up-regulation
CAMK_CASK_CASK_ST	O14936	CASK	O14936	CASK	S151	L148I	148	Missense	distal	-3	no	7.373	7.022	PhosphoSitePlus;EPSD	TCGA;ICGC;COSMIC	2.569	Down-regulation
CAMK_CASK_CASK_ST	O14936	CASK	O14936	CASK	S155	L148I	148	Missense	distal	-7	no	7.115	7.103	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	2.569	Down-regulation
CAMK_CASK_CASK_ST	O14936	CASK	O14936	CASK	S313	A310V	310	Missense	distal	-3	no	2.590	2.322	EPSD	TCGA;ICGC;COSMIC	2.569	Loss
CAMK_CASK_CASK_ST	O14936	CASK	O14936	CASK	S319	D323N	323	Missense	distal	4	no	1.952	2.899	EPSD	TCGA;ICGC;COSMIC	2.569	Gain
CAMK_CASK_CASK_ST	O14936	CASK	O14936	CASK	S394	P401L	401	Missense	distal	7	no	2.904	2.924	EPSD	TCGA;ICGC;COSMIC	2.569	Up-regulation
CAMK_CASK_CASK_ST	O14936	CASK	O14936	CASK	S394	D388G	388	Missense	distal	-6	no	2.904	2.985	EPSD	TCGA;ICGC;COSMIC	2.569	Up-regulation
CAMK_CASK_CASK_ST	O14936	CASK	O14936	CASK	S394	S394Y	394	Missense	central	0	yes	2.904	0.000	EPSD	TCGA;ICGC;COSMIC	2.569	Loss
CAMK_CASK_CASK_ST	O14936	CASK	O14936	CASK	S576	R580K	580	Missense	distal	4	no	1.724	2.627	EPSD	TCGA;ICGC;COSMIC	2.569	Gain
CAMK_CASK_CASK_ST	O14936	CASK	O14936	CASK	S596	H594Y	594	Missense	proximal	-2	no	2.754	2.780	EPSD	TCGA;ICGC;COSMIC	2.569	Up-regulation
CAMK_CASK_CASK_ST	O14936	CASK	O14936	CASK	S596	S602L	602	Missense	distal	6	no	2.754	2.455	EPSD	TCGA;ICGC;COSMIC;GDSC	2.569	Loss
CAMK_CASK_CASK_ST	O14936	CASK	O14936	CASK	S602	S606L	606	Missense	distal	4	no	3.566	2.372	EPSD	TCGA;COSMIC	2.569	Loss
CAMK_CASK_CASK_ST	O14936	CASK	O14936	CASK	S602	S602L	602	Missense	central	0	yes	3.566	0.000	EPSD	TCGA;ICGC;COSMIC;GDSC	2.569	Loss
TK_FGFR_FGFR3_Y	P35222	CTNNB1	P22607	FGFR3	Y333	Y333F	333	Missense	central	0	yes	0.000	0.000	EPSD	TCGA;COSMIC	0.000	Loss
TK_FGFR_FGFR3_Y	P60484	PTEN	P22607	FGFR3	Y27	Y27C	27	Missense	central	0	yes	0.000	0.000	EPSD	TCGA;ICGC;COSMIC	0.000	Loss
TK_FGFR_FGFR3_Y	P60484	PTEN	P22607	FGFR3	Y27	Y27D	27	Missense	central	0	yes	0.000	0.000	EPSD	TCGA;ICGC;COSMIC	0.000	Loss
TK_FGFR_FGFR3_Y	P60484	PTEN	P22607	FGFR3	Y46	Y46H	46	Missense	central	0	yes	0.000	0.000	EPSD	TCGA;ICGC;COSMIC;CCLE	0.000	Loss
TK_FGFR_FGFR3_Y	P60484	PTEN	P22607	FGFR3	Y68	Y68C	68	Missense	central	0	yes	0.000	0.000	EPSD	TCGA;ICGC;COSMIC	0.000	Loss
TK_FGFR_FGFR3_Y	P60484	PTEN	P22607	FGFR3	Y155	Y155C	155	Missense	central	0	yes	0.000	0.000	EPSD	TCGA;ICGC;COSMIC;GDSC;CCLE	0.000	Loss
TK_FGFR_FGFR3_Y	P60484	PTEN	P22607	FGFR3	Y177	Y177F	177	Missense	central	0	yes	0.000	0.000	EPSD	TCGA;ICGC;COSMIC	0.000	Loss
TK_FGFR_FGFR3_Y	P60484	PTEN	P22607	FGFR3	Y177	Y177D	177	Missense	central	0	yes	0.000	0.000	EPSD	TCGA;ICGC;COSMIC	0.000	Loss
TK_FGFR_FGFR3_Y	P60484	PTEN	P22607	FGFR3	Y178	Y178C	178	Missense	central	0	yes	0.000	0.000	EPSD	TCGA;ICGC;COSMIC	0.000	Loss
TK_FGFR_FGFR3_Y	P42224	STAT1	P22607	FGFR3	Y203	Y203H	203	Missense	central	0	yes	0.000	0.000	EPSD	TCGA;ICGC	0.000	Loss
Other_TLK_TLK2_ST	Q9Y294	ASF1A	Q86UE8	TLK2	S192	S192L	192	Missense	central	0	yes	4.645	0.000	PhosphoSitePlus	TCGA	1.183	Loss
Other_TLK_TLK2_ST	Q9Y294	ASF1A	Q86UE8	TLK2	S192	W186R	186	Missense	distal	-6	no	4.645	4.632	PhosphoSitePlus	TCGA;ICGC;COSMIC	1.183	Down-regulation
STE_STE7_MEK3_MAP2K6_ST	O15264	MAPK13	P52564	MAP2K6	T180	D176E	176	Missense	distal	-4	no	9.851	9.795	PhosphoSitePlus;EPSD	TCGA;COSMIC	1.858	Down-regulation
STE_STE7_MEK3_MAP2K6_ST	P52564	MAP2K6	P52564	MAP2K6	S35	D34Y	34	Missense	proximal	-1	no	2.336	2.189	EPSD	TCGA;ICGC;COSMIC	1.858	Down-regulation
STE_STE7_MEK3_MAP2K6_ST	P52564	MAP2K6	P52564	MAP2K6	S35	P30H	30	Missense	distal	-5	no	2.336	2.318	EPSD	TCGA;ICGC;COSMIC	1.858	Down-regulation
STE_STE7_MEK3_MAP2K6_ST	P52564	MAP2K6	P52564	MAP2K6	S201	C196S	196	Missense	distal	-5	no	2.269	2.299	EPSD	TCGA;COSMIC	1.858	Up-regulation
STE_STE7_MEK3_MAP2K6_ST	P52564	MAP2K6	P52564	MAP2K6	S201	D197N	197	Missense	distal	-4	no	2.269	2.194	EPSD	TCGA;COSMIC	1.858	Down-regulation
STE_STE7_MEK3_MAP2K6_ST	P52564	MAP2K6	P52564	MAP2K6	S201	S207Y	207	Missense	distal	6	no	2.269	2.215	EPSD	TCGA	1.858	Down-regulation
STE_STE7_MEK3_MAP2K6_ST	P52564	MAP2K6	P52564	MAP2K6	S207	K210R	210	Missense	distal	3	no	8.152	8.122	PhosphoSitePlus;EPSD	TCGA;COSMIC	1.858	Down-regulation
STE_STE7_MEK3_MAP2K6_ST	P52564	MAP2K6	P52564	MAP2K6	S207	S207Y	207	Missense	central	0	yes	8.152	0.000	PhosphoSitePlus;EPSD	TCGA	1.858	Loss
STE_STE7_MEK3_MAP2K6_ST	Q9ULV5	HSF4	P52564	MAP2K6	S298	G300E	300	Missense	proximal	2	no	1.489	1.865	EPSD	TCGA;ICGC;COSMIC	1.858	Gain
STE_STE7_MEK3_MAP2K6_ST	Q16539	MAPK14	P52564	MAP2K6	T180	R186K	186	Missense	distal	6	no	9.830	9.836	PhosphoSitePlus;EPSD	TCGA;ICGC;COSMIC	1.858	Up-regulation
STE_STE7_MEK3_MAP2K6_ST	Q16539	MAPK14	P52564	MAP2K6	T180	R173W	173	Missense	distal	-7	no	9.830	9.760	PhosphoSitePlus;EPSD	TCGA;ICGC;CCLE	1.858	Down-regulation
STE_STE7_MEK3_MAP2K6_ST	Q9NQU5	PAK6	P52564	MAP2K6	T326	P329L	329	Missense	distal	3	no	3.364	2.976	EPSD	TCGA;ICGC;COSMIC	1.858	Down-regulation
STE_STE7_MEK3_MAP2K6_ST	Q9NQU5	PAK6	P52564	MAP2K6	T326	P320S	320	Missense	distal	-6	no	3.364	3.345	EPSD	TCGA;ICGC;COSMIC	1.858	Down-regulation
STE_STE7_MEK3_MAP2K6_ST	Q9NQU5	PAK6	P52564	MAP2K6	T326	S324L	324	Missense	proximal	-2	no	3.364	3.338	EPSD	TCGA;ICGC;COSMIC	1.858	Down-regulation
STE_STE7_MEK3_MAP2K6_ST	Q9NQU5	PAK6	P52564	MAP2K6	T326	L333P	333	Missense	distal	7	no	3.364	3.365	EPSD	TCGA;ICGC	1.858	Up-regulation
TK_Csk_MATK_Y	P78324	SIRPA	P42679	MATK	Y429	L434Q	434	Missense	distal	5	no	5.372	5.449	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	1.382	Up-regulation
TK_Csk_MATK_Y	P78324	SIRPA	P42679	MATK	Y453	S455R	455	Missense	proximal	2	no	5.088	5.010	PhosphoSitePlus;EPSD	TCGA;ICGC;COSMIC	1.382	Down-regulation
TK_Csk_MATK_Y	P78324	SIRPA	P42679	MATK	Y453	S455T	455	Missense	proximal	2	no	5.088	5.052	PhosphoSitePlus;EPSD	TCGA;ICGC;COSMIC	1.382	Down-regulation
TK_Csk_MATK_Y	P78324	SIRPA	P42679	MATK	Y453	E446K	446	Missense	distal	-7	no	5.088	5.128	PhosphoSitePlus;EPSD	TCGA;ICGC;COSMIC	1.382	Up-regulation
TK_Csk_MATK_Y	P78324	SIRPA	P42679	MATK	Y453	S455I	455	Missense	proximal	2	no	5.088	4.969	PhosphoSitePlus;EPSD	TCGA;ICGC;COSMIC	1.382	Down-regulation
TK_Csk_MATK_Y	P07948	LYN	P42679	MATK	Y473	D474A	474	Missense	proximal	1	no	1.015	1.426	EPSD	TCGA;ICGC	1.382	Gain
TK_Csk_MATK_Y	P07948	LYN	P42679	MATK	Y508	Q509H	509	Missense	proximal	1	no	4.938	4.397	PhosphoSitePlus	TCGA;ICGC;COSMIC	1.382	Down-regulation
TK_Csk_MATK_Y	P07948	LYN	P42679	MATK	Y508	Q510L	510	Missense	proximal	2	no	4.938	4.728	PhosphoSitePlus	TCGA;ICGC;COSMIC	1.382	Down-regulation
CK1_VRK_VRK2_ST	P38432	COIL	Q86Y07	VRK2	T169	T169A	169	Missense	central	0	yes	48.054	0.000	EPSD	TCGA;ICGC;COSMIC	34.967	Loss
CK1_VRK_VRK2_ST	P38432	COIL	Q86Y07	VRK2	T169	D176G	176	Missense	distal	7	no	48.054	47.787	EPSD	TCGA;ICGC;COSMIC	34.967	Down-regulation
CK1_VRK_VRK2_ST	P38432	COIL	Q86Y07	VRK2	T172	T169A	169	Missense	distal	-3	no	38.608	38.919	EPSD	TCGA;ICGC;COSMIC	34.967	Up-regulation
CK1_VRK_VRK2_ST	P38432	COIL	Q86Y07	VRK2	T172	D176G	176	Missense	distal	4	no	38.608	37.982	EPSD	TCGA;ICGC;COSMIC	34.967	Down-regulation
CK1_VRK_VRK2_ST	P38432	COIL	Q86Y07	VRK2	S184	C191Y	191	Missense	distal	7	no	100.519	100.670	PhosphoSitePlus	TCGA;ICGC;COSMIC	34.967	Up-regulation
CK1_VRK_VRK2_ST	P38432	COIL	Q86Y07	VRK2	S184	K186T	186	Missense	proximal	2	no	100.519	95.563	PhosphoSitePlus	TCGA;ICGC;COSMIC	34.967	Down-regulation
CK1_VRK_VRK2_ST	P38432	COIL	Q86Y07	VRK2	S217	Q214K	214	Missense	distal	-3	no	36.934	33.443	EPSD	TCGA;ICGC;COSMIC	34.967	Loss
CK1_VRK_VRK2_ST	P38432	COIL	Q86Y07	VRK2	S217	Q214E	214	Missense	distal	-3	no	36.934	36.755	EPSD	TCGA;ICGC;COSMIC;CCLE	34.967	Down-regulation
CK1_VRK_VRK2_ST	P38432	COIL	Q86Y07	VRK2	S218	Q214K	214	Missense	distal	-4	no	45.794	45.322	EPSD	TCGA;ICGC;COSMIC	34.967	Down-regulation
CK1_VRK_VRK2_ST	P38432	COIL	Q86Y07	VRK2	S218	Q214E	214	Missense	distal	-4	no	45.794	45.741	EPSD	TCGA;ICGC;COSMIC;CCLE	34.967	Down-regulation
CK1_VRK_VRK2_ST	P38432	COIL	Q86Y07	VRK2	S256	D259N	259	Missense	distal	3	no	38.945	38.519	EPSD	TCGA;ICGC;COSMIC	34.967	Down-regulation
CK1_VRK_VRK2_ST	Q9UHP3	USP25	Q86Y07	VRK2	T680	T680K	680	Missense	central	0	yes	97.663	0.000	PhosphoSitePlus;EPSD	TCGA;ICGC;COSMIC	34.967	Loss
CK1_VRK_VRK2_ST	Q9UHP3	USP25	Q86Y07	VRK2	S725	A718T	718	Missense	distal	-7	no	42.104	42.145	EPSD	TCGA;ICGC;COSMIC	34.967	Up-regulation
CK1_VRK_VRK2_ST	Q9UHP3	USP25	Q86Y07	VRK2	S745	S750L	750	Missense	distal	5	no	103.353	102.606	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	34.967	Down-regulation
CK1_VRK_VRK2_ST	Q9UHP3	USP25	Q86Y07	VRK2	S745	R746I	746	Missense	proximal	1	no	103.353	102.412	EPSD;PhosphoSitePlus	TCGA	34.967	Down-regulation
CK1_VRK_VRK2_ST	O75531	BANF1	Q86Y07	VRK2	T2	Q5P	5	Missense	distal	3	no	63.938	63.541	PhosphoSitePlus;EPSD	TCGA;ICGC;COSMIC	34.967	Down-regulation
CK1_VRK_VRK2_ST	O75531	BANF1	Q86Y07	VRK2	T2	H7R	7	Missense	distal	5	no	63.938	64.403	PhosphoSitePlus;EPSD	TCGA;ICGC	34.967	Up-regulation
CK1_VRK_VRK2_ST	O75531	BANF1	Q86Y07	VRK2	T3	Q5P	5	Missense	proximal	2	no	70.420	73.450	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	34.967	Up-regulation
CK1_VRK_VRK2_ST	O75531	BANF1	Q86Y07	VRK2	T3	H7R	7	Missense	distal	4	no	70.420	70.106	EPSD;PhosphoSitePlus	TCGA;ICGC	34.967	Down-regulation
CK1_VRK_VRK2_ST	O75531	BANF1	Q86Y07	VRK2	S4	Q5P	5	Missense	proximal	1	no	62.339	62.045	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	34.967	Down-regulation
CK1_VRK_VRK2_ST	O75531	BANF1	Q86Y07	VRK2	S4	V11A	11	Missense	distal	7	no	62.339	62.220	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	34.967	Down-regulation
CK1_VRK_VRK2_ST	O75531	BANF1	Q86Y07	VRK2	S4	H7R	7	Missense	distal	3	no	62.339	62.564	EPSD;PhosphoSitePlus	TCGA;ICGC	34.967	Up-regulation
CK1_VRK_VRK2_ST	Q96EV8	DTNBP1	Q86Y07	VRK2	S53	G48V	48	Missense	distal	-5	no	44.147	42.877	EPSD	TCGA;ICGC;COSMIC	34.967	Down-regulation
CK1_VRK_VRK2_ST	Q96EV8	DTNBP1	Q86Y07	VRK2	S53	A60V	60	Missense	distal	7	no	44.147	44.266	EPSD	TCGA;ICGC;COSMIC	34.967	Up-regulation
CK1_VRK_VRK2_ST	Q96EV8	DTNBP1	Q86Y07	VRK2	S53	D57V	57	Missense	distal	4	no	44.147	44.115	EPSD	TCGA;ICGC;COSMIC	34.967	Down-regulation
CK1_VRK_VRK2_ST	Q96EV8	DTNBP1	Q86Y07	VRK2	T115	E112K	112	Missense	distal	-3	no	45.631	42.318	EPSD	TCGA;ICGC;COSMIC	34.967	Down-regulation
CK1_VRK_VRK2_ST	Q96EV8	DTNBP1	Q86Y07	VRK2	T115	S113F	113	Missense	proximal	-2	no	45.631	46.148	EPSD	TCGA;ICGC;COSMIC	34.967	Up-regulation
CK1_VRK_VRK2_ST	Q96EV8	DTNBP1	Q86Y07	VRK2	T115	A109T	109	Missense	distal	-6	no	45.631	46.221	EPSD	TCGA;ICGC;COSMIC;GDSC;CCLE	34.967	Up-regulation
CK1_VRK_VRK2_ST	Q96EV8	DTNBP1	Q86Y07	VRK2	T119	E112K	112	Missense	distal	-7	no	54.713	51.778	EPSD	TCGA;ICGC;COSMIC	34.967	Down-regulation
CK1_VRK_VRK2_ST	Q96EV8	DTNBP1	Q86Y07	VRK2	T119	S113F	113	Missense	distal	-6	no	54.713	56.134	EPSD	TCGA;ICGC;COSMIC	34.967	Up-regulation
AGC_DMPK_ROCK_ROCK1_ST	Q14160	SCRIB	Q13464	ROCK1	T475	P478S	478	Missense	distal	3	no	48.836	48.864	EPSD	TCGA;ICGC;COSMIC	31.796	Up-regulation
AGC_DMPK_ROCK_ROCK1_ST	Q14160	SCRIB	Q13464	ROCK1	T475	K482R	482	Missense	distal	7	no	48.836	48.210	EPSD	TCGA;ICGC;COSMIC	31.796	Down-regulation
AGC_DMPK_ROCK_ROCK1_ST	Q14160	SCRIB	Q13464	ROCK1	S493	E489K	489	Missense	distal	-4	no	33.216	36.883	EPSD	TCGA;ICGC;COSMIC	31.796	Up-regulation
AGC_DMPK_ROCK_ROCK1_ST	Q14160	SCRIB	Q13464	ROCK1	S493	E494K	494	Missense	proximal	1	no	33.216	32.371	EPSD	TCGA;ICGC;COSMIC;GDSC;CCLE	31.796	Down-regulation
AGC_DMPK_ROCK_ROCK1_ST	Q14160	SCRIB	Q13464	ROCK1	S493	P500A	500	Missense	distal	7	no	33.216	32.840	EPSD	TCGA;ICGC;COSMIC	31.796	Down-regulation
AGC_DMPK_ROCK_ROCK1_ST	Q14160	SCRIB	Q13464	ROCK1	S493	R492W	492	Missense	proximal	-1	no	33.216	31.263	EPSD	TCGA;ICGC;COSMIC	31.796	Loss
AGC_DMPK_ROCK_ROCK1_ST	Q14160	SCRIB	Q13464	ROCK1	T607	R601Q	601	Missense	distal	-6	no	46.730	42.805	EPSD	TCGA;ICGC;COSMIC	31.796	Down-regulation
AGC_DMPK_ROCK_ROCK1_ST	Q14160	SCRIB	Q13464	ROCK1	T883	T883I	883	Missense	central	0	yes	32.465	0.000	EPSD	TCGA;ICGC;COSMIC	31.796	Loss
AGC_DMPK_ROCK_ROCK1_ST	Q14160	SCRIB	Q13464	ROCK1	T883	G888V	888	Missense	distal	5	no	32.465	33.291	EPSD	TCGA;ICGC;COSMIC	31.796	Up-regulation
AGC_DMPK_ROCK_ROCK1_ST	Q14160	SCRIB	Q13464	ROCK1	T1130	P1129S	1129	Missense	proximal	-1	no	32.335	34.354	EPSD	TCGA;ICGC;COSMIC	31.796	Up-regulation
AGC_DMPK_ROCK_ROCK1_ST	Q14160	SCRIB	Q13464	ROCK1	T1130	D1128N	1128	Missense	proximal	-2	no	32.335	34.313	EPSD	TCGA;ICGC;COSMIC	31.796	Up-regulation
AGC_DMPK_ROCK_ROCK1_ST	Q14160	SCRIB	Q13464	ROCK1	T1130	S1137T	1137	Missense	distal	7	no	32.335	32.716	EPSD	TCGA;ICGC;COSMIC	31.796	Up-regulation
AGC_DMPK_ROCK_ROCK1_ST	Q14160	SCRIB	Q13464	ROCK1	T1130	A1123T	1123	Missense	distal	-7	no	32.335	32.392	EPSD	TCGA;ICGC;COSMIC	31.796	Up-regulation
AGC_DMPK_ROCK_ROCK1_ST	Q14160	SCRIB	Q13464	ROCK1	T1130	R1127H	1127	Missense	distal	-3	no	32.335	17.724	EPSD	TCGA;ICGC;COSMIC	31.796	Loss
AGC_DMPK_ROCK_ROCK1_ST	Q14160	SCRIB	Q13464	ROCK1	S1378	E1371K	1371	Missense	distal	-7	no	39.728	39.792	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	31.796	Up-regulation
AGC_DMPK_ROCK_ROCK1_ST	Q14160	SCRIB	Q13464	ROCK1	S1378	R1376C	1376	Missense	proximal	-2	no	39.728	6.870	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	31.796	Loss
AGC_DMPK_ROCK_ROCK1_ST	Q14160	SCRIB	Q13464	ROCK1	S1378	P1374L	1374	Missense	distal	-4	no	39.728	40.294	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	31.796	Up-regulation
AGC_DMPK_ROCK_ROCK1_ST	Q14160	SCRIB	Q13464	ROCK1	S1378	P1374S	1374	Missense	distal	-4	no	39.728	41.105	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	31.796	Up-regulation
AGC_DMPK_ROCK_ROCK1_ST	Q14160	SCRIB	Q13464	ROCK1	S1378	R1376H	1376	Missense	proximal	-2	no	39.728	28.592	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	31.796	Loss
AGC_DMPK_ROCK_ROCK1_ST	Q14160	SCRIB	Q13464	ROCK1	S1508	A1513T	1513	Missense	distal	5	no	38.412	38.179	PhosphoSitePlus;EPSD	TCGA;ICGC;COSMIC	31.796	Down-regulation
AGC_DMPK_ROCK_ROCK1_ST	P35241	RDX	Q13464	ROCK1	T66	D69Y	69	Missense	distal	3	no	36.036	36.095	EPSD	TCGA;ICGC	31.796	Up-regulation
AGC_DMPK_ROCK_ROCK1_ST	P35241	RDX	Q13464	ROCK1	T66	K63T	63	Missense	distal	-3	no	36.036	32.216	EPSD	TCGA;ICGC	31.796	Down-regulation
AGC_DMPK_ROCK_ROCK1_ST	P35241	RDX	Q13464	ROCK1	T66	K72I	72	Missense	distal	6	no	36.036	36.728	EPSD	TCGA;ICGC;COSMIC	31.796	Up-regulation
AGC_DMPK_ROCK_ROCK1_ST	P35241	RDX	Q13464	ROCK1	T66	K71R	71	Missense	distal	5	no	36.036	35.894	EPSD	TCGA;ICGC;COSMIC	31.796	Down-regulation
AGC_DMPK_ROCK_ROCK1_ST	P35241	RDX	Q13464	ROCK1	T564	R569Q	569	Missense	distal	5	no	33.014	33.853	PhosphoSitePlus	TCGA;ICGC	31.796	Up-regulation
AGC_DMPK_ROCK_ROCK1_ST	P35241	RDX	Q13464	ROCK1	T564	D560Y	560	Missense	distal	-4	no	33.014	33.315	PhosphoSitePlus	TCGA;COSMIC	31.796	Up-regulation
AGC_DMPK_ROCK_ROCK1_ST	P35241	RDX	Q13464	ROCK1	T564	R566Q	566	Missense	proximal	2	no	33.014	31.858	PhosphoSitePlus	TCGA;COSMIC	31.796	Down-regulation
AGC_DMPK_ROCK_ROCK1_ST	P35241	RDX	Q13464	ROCK1	T564	A557T	557	Missense	distal	-7	no	33.014	33.071	PhosphoSitePlus	TCGA;ICGC;COSMIC	31.796	Up-regulation
AGC_DMPK_ROCK_ROCK1_ST	P61587	RND3	Q13464	ROCK1	S7	R4I	4	Missense	distal	-3	no	40.635	28.378	EPSD;PhosphoSitePlus	TCGA;ICGC	31.796	Loss
AGC_DMPK_ROCK_ROCK1_ST	P61587	RND3	Q13464	ROCK1	S210	R216W	216	Missense	distal	6	no	34.644	36.122	EPSD	TCGA;COSMIC;CCLE	31.796	Up-regulation
AGC_DMPK_ROCK_ROCK1_ST	P61587	RND3	Q13464	ROCK1	S210	S210L	210	Missense	central	0	yes	34.644	0.000	EPSD	TCGA;COSMIC	31.796	Loss
AGC_DMPK_ROCK_ROCK1_ST	P61587	RND3	Q13464	ROCK1	S210	V205G	205	Missense	distal	-5	no	34.644	37.259	EPSD	TCGA;COSMIC	31.796	Up-regulation
AGC_DMPK_ROCK_ROCK1_ST	P61587	RND3	Q13464	ROCK1	S218	R216W	216	Missense	proximal	-2	no	51.293	50.208	EPSD;PhosphoSitePlus	TCGA;COSMIC;CCLE	31.796	Down-regulation
AGC_DMPK_ROCK_ROCK1_ST	P19634	SLC9A1	Q13464	ROCK1	S648	T653M	653	Missense	distal	5	no	35.012	35.477	EPSD	TCGA;ICGC;COSMIC	31.796	Up-regulation
AGC_DMPK_ROCK_ROCK1_ST	P19634	SLC9A1	Q13464	ROCK1	T653	T653M	653	Missense	central	0	yes	43.592	0.000	PhosphoSitePlus	TCGA;ICGC;COSMIC	31.796	Loss
AGC_DMPK_ROCK_ROCK1_ST	P19634	SLC9A1	Q13464	ROCK1	T685	T685M	685	Missense	central	0	yes	32.153	0.000	EPSD	TCGA;ICGC;COSMIC;GDSC;CCLE	31.796	Loss
AGC_DMPK_ROCK_ROCK1_ST	Q9NRY4	ARHGAP35	Q13464	ROCK1	T136	E142K	142	Missense	distal	6	no	37.806	37.119	EPSD	TCGA;ICGC;COSMIC	31.796	Down-regulation
AGC_DMPK_ROCK_ROCK1_ST	Q9NRY4	ARHGAP35	Q13464	ROCK1	T136	K130I	130	Missense	distal	-6	no	37.806	33.971	EPSD	TCGA	31.796	Down-regulation
AGC_DMPK_ROCK_ROCK1_ST	Q9NRY4	ARHGAP35	Q13464	ROCK1	S1072	Q1079E	1079	Missense	distal	7	no	39.561	39.747	EPSD	TCGA;ICGC;COSMIC	31.796	Up-regulation
AGC_DMPK_ROCK_ROCK1_ST	Q9NRY4	ARHGAP35	Q13464	ROCK1	S1074	Q1079E	1079	Missense	distal	5	no	33.640	33.646	EPSD	TCGA;ICGC;COSMIC	31.796	Up-regulation
AGC_DMPK_ROCK_ROCK1_ST	Q9NRY4	ARHGAP35	Q13464	ROCK1	S1150	V1152A	1152	Missense	proximal	2	no	41.805	41.099	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	31.796	Down-regulation
AGC_DMPK_ROCK_ROCK1_ST	Q9NRY4	ARHGAP35	Q13464	ROCK1	S1150	R1147H	1147	Missense	distal	-3	no	41.805	27.195	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	31.796	Loss
AGC_DMPK_ROCK_ROCK1_ST	Q9NRY4	ARHGAP35	Q13464	ROCK1	S1170	R1172Q	1172	Missense	proximal	2	no	40.317	39.161	EPSD	TCGA;ICGC;COSMIC	31.796	Down-regulation
AGC_DMPK_ROCK_ROCK1_ST	Q9NRY4	ARHGAP35	Q13464	ROCK1	S1170	S1176N	1176	Missense	distal	6	no	40.317	40.843	EPSD	TCGA;ICGC	31.796	Up-regulation
AGC_DMPK_ROCK_ROCK1_ST	Q9NRY4	ARHGAP35	Q13464	ROCK1	T1173	R1172Q	1172	Missense	proximal	-1	no	33.235	31.018	PhosphoSitePlus;EPSD	TCGA;ICGC;COSMIC	31.796	Loss
AGC_DMPK_ROCK_ROCK1_ST	Q9NRY4	ARHGAP35	Q13464	ROCK1	T1173	S1176N	1176	Missense	distal	3	no	33.235	33.218	PhosphoSitePlus;EPSD	TCGA;ICGC	31.796	Down-regulation
AGC_DMPK_ROCK_ROCK1_ST	Q9NRY4	ARHGAP35	Q13464	ROCK1	S1174	R1172Q	1172	Missense	proximal	-2	no	37.594	24.424	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	31.796	Loss
AGC_DMPK_ROCK_ROCK1_ST	Q9NRY4	ARHGAP35	Q13464	ROCK1	S1174	S1176N	1176	Missense	proximal	2	no	37.594	36.790	EPSD;PhosphoSitePlus	TCGA;ICGC	31.796	Down-regulation
AGC_DMPK_ROCK_ROCK1_ST	Q9NRY4	ARHGAP35	Q13464	ROCK1	S1176	R1172Q	1172	Missense	distal	-4	no	32.634	31.086	EPSD	TCGA;ICGC;COSMIC	31.796	Loss
AGC_DMPK_ROCK_ROCK1_ST	Q9NRY4	ARHGAP35	Q13464	ROCK1	S1176	S1176N	1176	Missense	central	0	yes	32.634	0.000	EPSD	TCGA;ICGC	31.796	Loss
AGC_DMPK_ROCK_ROCK1_ST	Q9NRY4	ARHGAP35	Q13464	ROCK1	S1236	I1237M	1237	Missense	proximal	1	no	40.710	40.872	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	31.796	Up-regulation
AGC_DMPK_ROCK_ROCK1_ST	Q9NRY4	ARHGAP35	Q13464	ROCK1	S1236	R1234P	1234	Missense	proximal	-2	no	40.710	21.229	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	31.796	Loss
AGC_DMPK_ROCK_ROCK1_ST	Q9NRY4	ARHGAP35	Q13464	ROCK1	S1290	E1291Q	1291	Missense	proximal	1	no	34.442	34.031	EPSD	TCGA;ICGC;COSMIC	31.796	Down-regulation
AGC_DMPK_ROCK_ROCK1_ST	Q9NRY4	ARHGAP35	Q13464	ROCK1	S1290	M1292V	1292	Missense	proximal	2	no	34.442	34.994	EPSD	TCGA;ICGC;COSMIC	31.796	Up-regulation
AGC_DMPK_ROCK_ROCK1_ST	Q9NRY4	ARHGAP35	Q13464	ROCK1	S1290	R1284W	1284	Missense	distal	-6	no	34.442	31.115	EPSD	TCGA;ICGC;COSMIC	31.796	Loss
AGC_DMPK_ROCK_ROCK1_ST	Q9NRY4	ARHGAP35	Q13464	ROCK1	S1290	E1293D	1293	Missense	distal	3	no	34.442	34.474	EPSD	TCGA;ICGC;COSMIC	31.796	Up-regulation
AGC_DMPK_ROCK_ROCK1_ST	Q9NRY4	ARHGAP35	Q13464	ROCK1	S1290	Q1296P	1296	Missense	distal	6	no	34.442	34.658	EPSD	TCGA;ICGC;COSMIC	31.796	Up-regulation
AGC_DMPK_ROCK_ROCK1_ST	Q9NRY4	ARHGAP35	Q13464	ROCK1	T1313	D1311Y	1311	Missense	proximal	-2	no	26.437	34.126	EPSD	TCGA;ICGC;COSMIC	31.796	Gain
AGC_DMPK_ROCK_ROCK1_ST	Q9Y613	FHOD1	Q13464	ROCK1	S357	R350W	350	Missense	distal	-7	no	38.076	37.831	EPSD	TCGA;ICGC;COSMIC	31.796	Down-regulation
AGC_DMPK_ROCK_ROCK1_ST	Q9Y613	FHOD1	Q13464	ROCK1	S357	R351Q	351	Missense	distal	-6	no	38.076	34.151	EPSD	TCGA;ICGC;COSMIC	31.796	Down-regulation
AGC_DMPK_ROCK_ROCK1_ST	Q9Y613	FHOD1	Q13464	ROCK1	S357	R354Q	354	Missense	distal	-3	no	38.076	33.193	EPSD	TCGA;ICGC;COSMIC	31.796	Down-regulation
AGC_DMPK_ROCK_ROCK1_ST	Q9Y613	FHOD1	Q13464	ROCK1	S367	G370D	370	Missense	distal	3	no	38.259	38.086	EPSD	TCGA;ICGC;COSMIC	31.796	Down-regulation
AGC_DMPK_ROCK_ROCK1_ST	Q9Y613	FHOD1	Q13464	ROCK1	S367	R365H	365	Missense	proximal	-2	no	38.259	27.123	EPSD	TCGA;ICGC;COSMIC	31.796	Loss
AGC_DMPK_ROCK_ROCK1_ST	Q9Y613	FHOD1	Q13464	ROCK1	S367	R366C	366	Missense	proximal	-1	no	38.259	33.978	EPSD	TCGA;ICGC;COSMIC	31.796	Down-regulation
AGC_DMPK_ROCK_ROCK1_ST	Q9Y613	FHOD1	Q13464	ROCK1	S367	R366H	366	Missense	proximal	-1	no	38.259	35.690	EPSD	TCGA;ICGC;COSMIC	31.796	Down-regulation
AGC_DMPK_ROCK_ROCK1_ST	Q9Y613	FHOD1	Q13464	ROCK1	S874	P872R	872	Missense	proximal	-2	no	12.748	32.229	EPSD	TCGA;ICGC;COSMIC	31.796	Gain
AGC_DMPK_ROCK_ROCK1_ST	Q9Y613	FHOD1	Q13464	ROCK1	T1010	R1005H	1005	Missense	distal	-5	no	32.912	31.685	EPSD	TCGA;ICGC;COSMIC	31.796	Loss
AGC_DMPK_ROCK_ROCK1_ST	Q9Y613	FHOD1	Q13464	ROCK1	T1016	E1019K	1019	Missense	distal	3	no	34.517	34.807	EPSD	TCGA;ICGC;COSMIC	31.796	Up-regulation
AGC_DMPK_ROCK_ROCK1_ST	Q9Y613	FHOD1	Q13464	ROCK1	S1052	H1050N	1050	Missense	proximal	-2	no	37.714	38.560	EPSD	TCGA;ICGC;COSMIC	31.796	Up-regulation
AGC_DMPK_ROCK_ROCK1_ST	Q9Y613	FHOD1	Q13464	ROCK1	S1052	K1054N	1054	Missense	proximal	2	no	37.714	35.717	EPSD	TCGA;ICGC;COSMIC	31.796	Down-regulation
AGC_DMPK_ROCK_ROCK1_ST	Q9Y613	FHOD1	Q13464	ROCK1	S1055	H1050N	1050	Missense	distal	-5	no	34.981	34.254	EPSD	TCGA;ICGC;COSMIC	31.796	Down-regulation
AGC_DMPK_ROCK_ROCK1_ST	Q9Y613	FHOD1	Q13464	ROCK1	S1055	K1054N	1054	Missense	proximal	-1	no	34.981	32.611	EPSD	TCGA;ICGC;COSMIC	31.796	Down-regulation
AGC_DMPK_ROCK_ROCK1_ST	Q9Y613	FHOD1	Q13464	ROCK1	S1131	R1132H	1132	Missense	proximal	1	no	37.343	37.902	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	31.796	Up-regulation
AGC_DMPK_ROCK_ROCK1_ST	Q9Y613	FHOD1	Q13464	ROCK1	S1131	R1128C	1128	Missense	distal	-3	no	37.343	12.058	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	31.796	Loss
AGC_DMPK_ROCK_ROCK1_ST	Q9Y613	FHOD1	Q13464	ROCK1	S1131	R1135C	1135	Missense	distal	4	no	37.343	36.157	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	31.796	Down-regulation
AGC_DMPK_ROCK_ROCK1_ST	Q9Y613	FHOD1	Q13464	ROCK1	S1131	R1132C	1132	Missense	proximal	1	no	37.343	38.139	EPSD;PhosphoSitePlus	TCGA;ICGC	31.796	Up-regulation
AGC_DMPK_ROCK_ROCK1_ST	Q9Y613	FHOD1	Q13464	ROCK1	S1137	T1141M	1141	Missense	distal	4	no	44.904	44.951	PhosphoSitePlus;EPSD	TCGA;ICGC;COSMIC	31.796	Up-regulation
AGC_DMPK_ROCK_ROCK1_ST	Q9Y613	FHOD1	Q13464	ROCK1	S1137	L1142F	1142	Missense	distal	5	no	44.904	44.890	PhosphoSitePlus;EPSD	TCGA;ICGC;COSMIC	31.796	Down-regulation
AGC_DMPK_ROCK_ROCK1_ST	Q9Y613	FHOD1	Q13464	ROCK1	S1137	R1132H	1132	Missense	distal	-5	no	44.904	43.677	PhosphoSitePlus;EPSD	TCGA;ICGC;COSMIC	31.796	Down-regulation
AGC_DMPK_ROCK_ROCK1_ST	Q9Y613	FHOD1	Q13464	ROCK1	S1137	R1135C	1135	Missense	proximal	-2	no	44.904	12.046	PhosphoSitePlus;EPSD	TCGA;ICGC;COSMIC	31.796	Loss
AGC_DMPK_ROCK_ROCK1_ST	Q9Y613	FHOD1	Q13464	ROCK1	S1137	R1132C	1132	Missense	distal	-5	no	44.904	39.271	PhosphoSitePlus;EPSD	TCGA;ICGC	31.796	Down-regulation
AGC_DMPK_ROCK_ROCK1_ST	Q9Y613	FHOD1	Q13464	ROCK1	T1141	T1141M	1141	Missense	central	0	yes	50.072	0.000	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	31.796	Loss
AGC_DMPK_ROCK_ROCK1_ST	Q9Y613	FHOD1	Q13464	ROCK1	T1141	L1142F	1142	Missense	proximal	1	no	50.072	50.041	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	31.796	Down-regulation
AGC_DMPK_ROCK_ROCK1_ST	Q9Y613	FHOD1	Q13464	ROCK1	T1141	R1135C	1135	Missense	distal	-6	no	50.072	41.038	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	31.796	Down-regulation
AGC_DMPK_ROCK_ROCK1_ST	Q8N264	ARHGAP24	Q13464	ROCK1	T97	H100Y	100	Missense	distal	3	no	39.339	39.262	EPSD	TCGA;ICGC;COSMIC	31.796	Down-regulation
AGC_DMPK_ROCK_ROCK1_ST	Q8N264	ARHGAP24	Q13464	ROCK1	T97	L104F	104	Missense	distal	7	no	39.339	39.923	EPSD	TCGA;ICGC;COSMIC	31.796	Up-regulation
AGC_DMPK_ROCK_ROCK1_ST	Q8N264	ARHGAP24	Q13464	ROCK1	T97	G90R	90	Missense	distal	-7	no	39.339	39.503	EPSD	TCGA;COSMIC	31.796	Up-regulation
AGC_DMPK_ROCK_ROCK1_ST	Q8N264	ARHGAP24	Q13464	ROCK1	T97	D92N	92	Missense	distal	-5	no	39.339	40.106	EPSD	TCGA;ICGC;COSMIC	31.796	Up-regulation
AGC_DMPK_ROCK_ROCK1_ST	Q8N264	ARHGAP24	Q13464	ROCK1	T97	R93Q	93	Missense	distal	-4	no	39.339	37.792	EPSD	TCGA;ICGC;COSMIC;CCLE	31.796	Down-regulation
AGC_DMPK_ROCK_ROCK1_ST	Q8N264	ARHGAP24	Q13464	ROCK1	S102	H100Y	100	Missense	proximal	-2	no	28.843	35.400	EPSD	TCGA;ICGC;COSMIC	31.796	Gain
AGC_DMPK_ROCK_ROCK1_ST	Q8N264	ARHGAP24	Q13464	ROCK1	S108	L104F	104	Missense	distal	-4	no	34.488	33.273	EPSD	TCGA;ICGC;COSMIC	31.796	Down-regulation
AGC_DMPK_ROCK_ROCK1_ST	Q8N264	ARHGAP24	Q13464	ROCK1	S108	L105F	105	Missense	distal	-3	no	34.488	30.452	EPSD	TCGA;ICGC;COSMIC	31.796	Loss
AGC_DMPK_ROCK_ROCK1_ST	Q8N264	ARHGAP24	Q13464	ROCK1	S108	Q110K	110	Missense	proximal	2	no	34.488	35.970	EPSD	TCGA;ICGC;COSMIC	31.796	Up-regulation
AGC_DMPK_ROCK_ROCK1_ST	Q8N264	ARHGAP24	Q13464	ROCK1	S391	L395I	395	Missense	distal	4	no	35.961	36.919	PhosphoSitePlus;EPSD	TCGA;ICGC	31.796	Up-regulation
AGC_DMPK_ROCK_ROCK1_ST	Q8N264	ARHGAP24	Q13464	ROCK1	S391	S391F	391	Missense	central	0	yes	35.961	0.000	PhosphoSitePlus;EPSD	TCGA;ICGC;COSMIC	31.796	Loss
AGC_DMPK_ROCK_ROCK1_ST	Q8N264	ARHGAP24	Q13464	ROCK1	S402	L395I	395	Missense	distal	-7	no	34.490	34.526	EPSD;PhosphoSitePlus	TCGA;ICGC	31.796	Up-regulation
AGC_DMPK_ROCK_ROCK1_ST	Q8N264	ARHGAP24	Q13464	ROCK1	S402	K404N	404	Missense	proximal	2	no	34.490	32.494	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	31.796	Down-regulation
AGC_DMPK_ROCK_ROCK1_ST	Q8N264	ARHGAP24	Q13464	ROCK1	S437	E444D	444	Missense	distal	7	no	33.437	33.683	EPSD;PhosphoSitePlus	TCGA;ICGC	31.796	Up-regulation
AGC_DMPK_ROCK_ROCK1_ST	Q8N264	ARHGAP24	Q13464	ROCK1	S462	R461K	461	Missense	proximal	-1	no	38.776	38.838	EPSD	TCGA;ICGC;COSMIC	31.796	Up-regulation
AGC_DMPK_ROCK_ROCK1_ST	Q8N264	ARHGAP24	Q13464	ROCK1	S463	R461K	461	Missense	proximal	-2	no	38.548	30.797	EPSD	TCGA;ICGC;COSMIC	31.796	Loss
AGC_DMPK_ROCK_ROCK1_ST	Q8N264	ARHGAP24	Q13464	ROCK1	S464	R461K	461	Missense	distal	-3	no	40.351	36.640	EPSD	TCGA;ICGC;COSMIC	31.796	Down-regulation
AGC_DMPK_ROCK_ROCK1_ST	Q8N264	ARHGAP24	Q13464	ROCK1	S530	D533N	533	Missense	distal	3	no	36.043	36.122	EPSD	TCGA	31.796	Up-regulation
AGC_DMPK_ROCK_ROCK1_ST	Q8N264	ARHGAP24	Q13464	ROCK1	S530	Q525P	525	Missense	distal	-5	no	36.043	33.570	EPSD	TCGA;ICGC;COSMIC	31.796	Down-regulation
AGC_DMPK_ROCK_ROCK1_ST	Q8N264	ARHGAP24	Q13464	ROCK1	S611	D606Y	606	Missense	distal	-5	no	31.857	33.250	EPSD	TCGA;ICGC;COSMIC	31.796	Up-regulation
AGC_DMPK_ROCK_ROCK1_ST	Q8N264	ARHGAP24	Q13464	ROCK1	S611	D612H	612	Missense	proximal	1	no	31.857	31.248	EPSD	TCGA;ICGC;COSMIC	31.796	Loss
AGC_DMPK_ROCK_ROCK1_ST	Q8N264	ARHGAP24	Q13464	ROCK1	S611	S615I	615	Missense	distal	4	no	31.857	31.522	EPSD	TCGA;ICGC	31.796	Loss
AGC_DMPK_ROCK_ROCK1_ST	Q8N264	ARHGAP24	Q13464	ROCK1	T624	R619Q	619	Missense	distal	-5	no	38.769	37.295	EPSD	TCGA;ICGC;COSMIC	31.796	Down-regulation
AGC_DMPK_ROCK_ROCK1_ST	Q8N264	ARHGAP24	Q13464	ROCK1	T624	S620I	620	Missense	distal	-4	no	38.769	38.734	EPSD	TCGA;ICGC;COSMIC	31.796	Down-regulation
AGC_DMPK_ROCK_ROCK1_ST	Q8N264	ARHGAP24	Q13464	ROCK1	S625	R619Q	619	Missense	distal	-6	no	38.369	34.444	EPSD	TCGA;ICGC;COSMIC	31.796	Down-regulation
AGC_DMPK_ROCK_ROCK1_ST	Q8N264	ARHGAP24	Q13464	ROCK1	S625	S620I	620	Missense	distal	-5	no	38.369	38.385	EPSD	TCGA;ICGC;COSMIC	31.796	Up-regulation
AGC_DMPK_ROCK_ROCK1_ST	Q8N264	ARHGAP24	Q13464	ROCK1	S627	S620I	620	Missense	distal	-7	no	35.021	35.070	EPSD	TCGA;ICGC;COSMIC	31.796	Up-regulation
AGC_DMPK_ROCK_ROCK1_ST	P15311	EZR	Q13464	ROCK1	S66	K60M	60	Missense	distal	-6	no	37.158	37.011	EPSD	TCGA;ICGC;COSMIC	31.796	Down-regulation
AGC_DMPK_ROCK_ROCK1_ST	P15311	EZR	Q13464	ROCK1	T325	R320W	320	Missense	distal	-5	no	36.469	34.187	EPSD	TCGA;ICGC;COSMIC	31.796	Down-regulation
AGC_DMPK_ROCK_ROCK1_ST	P15311	EZR	Q13464	ROCK1	T325	R330T	330	Missense	distal	5	no	36.469	36.923	EPSD	TCGA;ICGC;COSMIC	31.796	Up-regulation
AGC_DMPK_ROCK_ROCK1_ST	P15311	EZR	Q13464	ROCK1	T332	R330T	330	Missense	proximal	-2	no	33.836	20.562	EPSD	TCGA;ICGC;COSMIC	31.796	Loss
AGC_DMPK_ROCK_ROCK1_ST	P15311	EZR	Q13464	ROCK1	S366	K359N	359	Missense	distal	-7	no	37.457	37.335	EPSD	TCGA;ICGC;COSMIC	31.796	Down-regulation
AGC_DMPK_ROCK_ROCK1_ST	P15311	EZR	Q13464	ROCK1	S366	E362K	362	Missense	distal	-4	no	37.457	41.124	EPSD	TCGA;ICGC;COSMIC	31.796	Up-regulation
AGC_DMPK_ROCK_ROCK1_ST	P15311	EZR	Q13464	ROCK1	S366	E364D	364	Missense	proximal	-2	no	37.457	38.185	EPSD	TCGA;ICGC	31.796	Up-regulation
AGC_DMPK_ROCK_ROCK1_ST	P15311	EZR	Q13464	ROCK1	T533	V527M	527	Missense	distal	-6	no	31.196	35.029	EPSD	TCGA;ICGC;COSMIC	31.796	Gain
AGC_DMPK_ROCK_ROCK1_ST	P15311	EZR	Q13464	ROCK1	T567	R562Q	562	Missense	distal	-5	no	33.323	31.850	PhosphoSitePlus	TCGA;ICGC	31.796	Down-regulation
AGC_DMPK_ROCK_ROCK1_ST	P15311	EZR	Q13464	ROCK1	T567	R569Q	569	Missense	proximal	2	no	33.323	32.167	PhosphoSitePlus	TCGA;ICGC;COSMIC	31.796	Down-regulation
AGC_DMPK_ROCK_ROCK1_ST	P15311	EZR	Q13464	ROCK1	T576	R569Q	569	Missense	distal	-7	no	32.964	32.882	EPSD	TCGA;ICGC;COSMIC	31.796	Down-regulation
AGC_DMPK_ROCK_ROCK1_ST	P14136	GFAP	Q13464	ROCK1	S13	V15I	15	Missense	proximal	2	no	41.059	39.754	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	31.796	Down-regulation
AGC_DMPK_ROCK_ROCK1_ST	P14136	GFAP	Q13464	ROCK1	S13	E19K	19	Missense	distal	6	no	41.059	40.373	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	31.796	Down-regulation
AGC_DMPK_ROCK_ROCK1_ST	P14136	GFAP	Q13464	ROCK1	S16	V15I	15	Missense	proximal	-1	no	33.905	33.565	EPSD	TCGA;ICGC;COSMIC	31.796	Down-regulation
AGC_DMPK_ROCK_ROCK1_ST	P14136	GFAP	Q13464	ROCK1	S16	E19K	19	Missense	distal	3	no	33.905	34.195	EPSD	TCGA;ICGC;COSMIC	31.796	Up-regulation
AGC_DMPK_ROCK_ROCK1_ST	P14136	GFAP	Q13464	ROCK1	S38	R41L	41	Missense	distal	3	no	39.789	39.493	PhosphoSitePlus;EPSD	TCGA;ICGC;COSMIC	31.796	Down-regulation
AGC_DMPK_ROCK_ROCK1_ST	P14136	GFAP	Q13464	ROCK1	S38	G34A	34	Missense	distal	-4	no	39.789	39.478	PhosphoSitePlus;EPSD	TCGA;ICGC;COSMIC	31.796	Down-regulation
AGC_DMPK_ROCK_ROCK1_ST	P14136	GFAP	Q13464	ROCK1	S38	R36C	36	Missense	proximal	-2	no	39.789	6.931	PhosphoSitePlus;EPSD	TCGA;ICGC;COSMIC	31.796	Loss
AGC_DMPK_ROCK_ROCK1_ST	P14136	GFAP	Q13464	ROCK1	S38	G32S	32	Missense	distal	-6	no	39.789	38.248	PhosphoSitePlus;EPSD	TCGA;ICGC	31.796	Down-regulation
AGC_DMPK_ROCK_ROCK1_ST	P14136	GFAP	Q13464	ROCK1	S38	S38F	38	Missense	central	0	yes	39.789	0.000	PhosphoSitePlus;EPSD	TCGA;ICGC;COSMIC	31.796	Loss
AGC_DMPK_ROCK_ROCK1_ST	P60484	PTEN	Q13464	ROCK1	S179	R173C	173	Missense	distal	-6	no	43.618	34.584	EPSD	TCGA;ICGC;COSMIC;GDSC;CCLE	31.796	Down-regulation
AGC_DMPK_ROCK_ROCK1_ST	P60484	PTEN	Q13464	ROCK1	S179	R173H	173	Missense	distal	-6	no	43.618	40.099	EPSD	TCGA;ICGC;COSMIC;GDSC;CCLE	31.796	Down-regulation
AGC_DMPK_ROCK_ROCK1_ST	P60484	PTEN	Q13464	ROCK1	S179	Y178C	178	Missense	proximal	-1	no	43.618	41.691	EPSD	TCGA;ICGC;COSMIC	31.796	Down-regulation
AGC_DMPK_ROCK_ROCK1_ST	P60484	PTEN	Q13464	ROCK1	S179	Y177F	177	Missense	proximal	-2	no	43.618	36.750	EPSD	TCGA;ICGC;COSMIC	31.796	Down-regulation
AGC_DMPK_ROCK_ROCK1_ST	P60484	PTEN	Q13464	ROCK1	S179	R173L	173	Missense	distal	-6	no	43.618	37.724	EPSD	TCGA;ICGC;COSMIC	31.796	Down-regulation
AGC_DMPK_ROCK_ROCK1_ST	P60484	PTEN	Q13464	ROCK1	S179	L181P	181	Missense	proximal	2	no	43.618	44.679	EPSD	TCGA;ICGC;COSMIC	31.796	Up-regulation
AGC_DMPK_ROCK_ROCK1_ST	P60484	PTEN	Q13464	ROCK1	S179	Y177D	177	Missense	proximal	-2	no	43.618	35.928	EPSD	TCGA;ICGC;COSMIC	31.796	Down-regulation
AGC_DMPK_ROCK_ROCK1_ST	P60484	PTEN	Q13464	ROCK1	S227	R233Q	233	Missense	distal	6	no	33.700	34.817	EPSD	TCGA;ICGC;COSMIC;GDSC;CCLE	31.796	Up-regulation
AGC_DMPK_ROCK_ROCK1_ST	P60484	PTEN	Q13464	ROCK1	S227	G230E	230	Missense	distal	3	no	33.700	33.496	EPSD	TCGA;ICGC;COSMIC	31.796	Down-regulation
AGC_DMPK_ROCK_ROCK1_ST	P60484	PTEN	Q13464	ROCK1	S227	T232A	232	Missense	distal	5	no	33.700	33.933	EPSD	TCGA;ICGC;COSMIC;GDSC;CCLE	31.796	Up-regulation
AGC_DMPK_ROCK_ROCK1_ST	P60484	PTEN	Q13464	ROCK1	S229	R233Q	233	Missense	distal	4	no	35.730	34.291	PhosphoSitePlus;EPSD	TCGA;ICGC;COSMIC;GDSC;CCLE	31.796	Down-regulation
AGC_DMPK_ROCK_ROCK1_ST	P60484	PTEN	Q13464	ROCK1	S229	G230E	230	Missense	proximal	1	no	35.730	36.175	PhosphoSitePlus;EPSD	TCGA;ICGC;COSMIC	31.796	Up-regulation
AGC_DMPK_ROCK_ROCK1_ST	P60484	PTEN	Q13464	ROCK1	S229	T232A	232	Missense	distal	3	no	35.730	35.583	PhosphoSitePlus;EPSD	TCGA;ICGC;COSMIC;GDSC;CCLE	31.796	Down-regulation
AGC_DMPK_ROCK_ROCK1_ST	P60484	PTEN	Q13464	ROCK1	T232	R233Q	233	Missense	proximal	1	no	37.654	38.153	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC;GDSC;CCLE	31.796	Up-regulation
AGC_DMPK_ROCK_ROCK1_ST	P60484	PTEN	Q13464	ROCK1	T232	G230E	230	Missense	proximal	-2	no	37.654	34.416	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	31.796	Down-regulation
AGC_DMPK_ROCK_ROCK1_ST	P60484	PTEN	Q13464	ROCK1	T232	M239R	239	Missense	distal	7	no	37.654	35.841	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	31.796	Down-regulation
AGC_DMPK_ROCK_ROCK1_ST	P60484	PTEN	Q13464	ROCK1	T232	T232A	232	Missense	central	0	yes	37.654	0.000	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC;GDSC;CCLE	31.796	Loss
AGC_DMPK_ROCK_ROCK1_ST	P60484	PTEN	Q13464	ROCK1	T232	M239V	239	Missense	distal	7	no	37.654	37.746	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	31.796	Up-regulation
AGC_DMPK_ROCK_ROCK1_ST	P60484	PTEN	Q13464	ROCK1	S338	R335P	335	Missense	distal	-3	no	42.148	24.379	EPSD	TCGA;ICGC;COSMIC	31.796	Loss
AGC_DMPK_ROCK_ROCK1_ST	P60484	PTEN	Q13464	ROCK1	S338	F341V	341	Missense	distal	3	no	42.148	42.238	EPSD	TCGA;ICGC;COSMIC;GDSC;CCLE	31.796	Up-regulation
AGC_DMPK_ROCK_ROCK1_ST	P60484	PTEN	Q13464	ROCK1	S338	K342N	342	Missense	distal	4	no	42.148	40.761	EPSD	TCGA;ICGC;COSMIC	31.796	Down-regulation
AGC_DMPK_ROCK_ROCK1_ST	P60484	PTEN	Q13464	ROCK1	S338	F337I	337	Missense	proximal	-1	no	42.148	42.775	EPSD	TCGA;ICGC;COSMIC	31.796	Up-regulation
AGC_DMPK_ROCK_ROCK1_ST	P60484	PTEN	Q13464	ROCK1	S338	F341C	341	Missense	distal	3	no	42.148	42.225	EPSD	TCGA;ICGC;COSMIC	31.796	Up-regulation
AGC_DMPK_ROCK_ROCK1_ST	P60484	PTEN	Q13464	ROCK1	S380	E373K	373	Missense	distal	-7	no	37.938	38.002	EPSD	TCGA;ICGC	31.796	Up-regulation
AGC_DMPK_ROCK_ROCK1_ST	P17661	DES	Q13464	ROCK1	S12	R10H	10	Missense	proximal	-2	no	38.150	27.014	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	31.796	Loss
AGC_DMPK_ROCK_ROCK1_ST	P17661	DES	Q13464	ROCK1	S13	R10H	10	Missense	distal	-3	no	32.838	18.228	EPSD	TCGA;ICGC;COSMIC	31.796	Loss
AGC_DMPK_ROCK_ROCK1_ST	P17661	DES	Q13464	ROCK1	T17	R10H	10	Missense	distal	-7	no	38.877	38.714	PhosphoSitePlus;EPSD	TCGA;ICGC;COSMIC	31.796	Down-regulation
AGC_DMPK_ROCK_ROCK1_ST	P17661	DES	Q13464	ROCK1	S60	G61V	61	Missense	proximal	1	no	45.968	46.667	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	31.796	Up-regulation
AGC_DMPK_ROCK_ROCK1_ST	P17661	DES	Q13464	ROCK1	S68	G61V	61	Missense	distal	-7	no	31.988	31.920	EPSD	TCGA;ICGC;COSMIC	31.796	Down-regulation
AGC_DMPK_ROCK_ROCK1_ST	P17661	DES	Q13464	ROCK1	T76	R78H	78	Missense	proximal	2	no	37.343	35.188	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	31.796	Down-regulation
AGC_DMPK_ROCK_ROCK1_ST	P17661	DES	Q13464	ROCK1	T77	R78H	78	Missense	proximal	1	no	32.526	33.086	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	31.796	Up-regulation
AGC_DMPK_ROCK_ROCK1_ST	P17661	DES	Q13464	ROCK1	S81	R78H	78	Missense	distal	-3	no	34.041	19.430	EPSD	TCGA;ICGC;COSMIC	31.796	Loss
AGC_DMPK_ROCK_ROCK1_ST	P17661	DES	Q13464	ROCK1	S438	K444T	444	Missense	distal	6	no	32.643	33.488	EPSD	TCGA;ICGC;COSMIC	31.796	Up-regulation
AGC_DMPK_ROCK_ROCK1_ST	Q14CB8	ARHGAP19	Q13464	ROCK1	S422	K416M	416	Missense	distal	-6	no	36.767	36.619	PhosphoSitePlus	TCGA;ICGC;COSMIC	31.796	Down-regulation
AGC_DMPK_ROCK_ROCK1_ST	Q14CB8	ARHGAP19	Q13464	ROCK1	S422	R429Q	429	Missense	distal	7	no	36.767	37.771	PhosphoSitePlus	TCGA;ICGC	31.796	Up-regulation
AGC_DMPK_ROCK_ROCK1_ST	Q14CB8	ARHGAP19	Q13464	ROCK1	S422	R419C	419	Missense	distal	-3	no	36.767	11.482	PhosphoSitePlus	TCGA;ICGC;COSMIC;GDSC;CCLE	31.796	Loss
AGC_DMPK_ROCK_ROCK1_ST	Q14CB8	ARHGAP19	Q13464	ROCK1	S424	R429Q	429	Missense	distal	5	no	34.748	35.587	EPSD	TCGA;ICGC	31.796	Up-regulation
AGC_DMPK_ROCK_ROCK1_ST	Q14CB8	ARHGAP19	Q13464	ROCK1	S424	R419C	419	Missense	distal	-5	no	34.748	29.114	EPSD	TCGA;ICGC;COSMIC;GDSC;CCLE	31.796	Loss
AGC_DMPK_ROCK_ROCK1_ST	Q14CB8	ARHGAP19	Q13464	ROCK1	S438	K440N	440	Missense	proximal	2	no	35.741	33.745	EPSD	TCGA;ICGC;COSMIC	31.796	Down-regulation
AGC_DMPK_ROCK_ROCK1_ST	Q14CB8	ARHGAP19	Q13464	ROCK1	S438	M436I	436	Missense	proximal	-2	no	35.741	21.644	EPSD	TCGA;ICGC;COSMIC	31.796	Loss
AGC_DMPK_ROCK_ROCK1_ST	Q14CB8	ARHGAP19	Q13464	ROCK1	S438	Q435K	435	Missense	distal	-3	no	35.741	36.913	EPSD	TCGA;ICGC;COSMIC	31.796	Up-regulation
AGC_DMPK_ROCK_ROCK1_ST	Q14CB8	ARHGAP19	Q13464	ROCK1	S438	P445L	445	Missense	distal	7	no	35.741	35.295	EPSD	TCGA;ICGC;COSMIC	31.796	Down-regulation
AGC_DMPK_ROCK_ROCK1_ST	Q14CB8	ARHGAP19	Q13464	ROCK1	S438	N444I	444	Missense	distal	6	no	35.741	35.502	EPSD	TCGA;ICGC;COSMIC	31.796	Down-regulation
AGC_DMPK_ROCK_ROCK1_ST	Q14CB8	ARHGAP19	Q13464	ROCK1	T446	K440N	440	Missense	distal	-6	no	33.960	31.127	EPSD	TCGA;ICGC;COSMIC	31.796	Loss
AGC_DMPK_ROCK_ROCK1_ST	Q14CB8	ARHGAP19	Q13464	ROCK1	T446	P445L	445	Missense	proximal	-1	no	33.960	33.226	EPSD	TCGA;ICGC;COSMIC	31.796	Down-regulation
AGC_DMPK_ROCK_ROCK1_ST	Q14CB8	ARHGAP19	Q13464	ROCK1	T446	N444I	444	Missense	proximal	-2	no	33.960	22.390	EPSD	TCGA;ICGC;COSMIC	31.796	Loss
AGC_DMPK_ROCK_ROCK1_ST	O14950	MYL12B	Q13464	ROCK1	T10	K7N	7	Missense	distal	-3	no	34.832	29.263	EPSD	TCGA;ICGC;COSMIC	31.796	Loss
AGC_DMPK_ROCK_ROCK1_ST	O14950	MYL12B	Q13464	ROCK1	T10	K9E	9	Missense	proximal	-1	no	34.832	30.592	EPSD	TCGA;ICGC;COSMIC	31.796	Loss
AGC_DMPK_ROCK_ROCK1_ST	O14950	MYL12B	Q13464	ROCK1	T10	R17C	17	Missense	distal	7	no	34.832	36.210	EPSD	TCGA;ICGC;COSMIC	31.796	Up-regulation
AGC_DMPK_ROCK_ROCK1_ST	O14950	MYL12B	Q13464	ROCK1	T10	A6T	6	Missense	distal	-4	no	34.832	35.033	EPSD	TCGA;ICGC;COSMIC;GDSC;CCLE	31.796	Up-regulation
AGC_DMPK_ROCK_ROCK1_ST	O14950	MYL12B	Q13464	ROCK1	T11	K7N	7	Missense	distal	-4	no	36.960	34.820	EPSD	TCGA;ICGC;COSMIC	31.796	Down-regulation
AGC_DMPK_ROCK_ROCK1_ST	O14950	MYL12B	Q13464	ROCK1	T11	K9E	9	Missense	proximal	-2	no	36.960	31.716	EPSD	TCGA;ICGC;COSMIC	31.796	Loss
AGC_DMPK_ROCK_ROCK1_ST	O14950	MYL12B	Q13464	ROCK1	T11	R17C	17	Missense	distal	6	no	36.960	38.158	EPSD	TCGA;ICGC;COSMIC	31.796	Up-regulation
AGC_DMPK_ROCK_ROCK1_ST	O14950	MYL12B	Q13464	ROCK1	T11	A6T	6	Missense	distal	-5	no	36.960	36.398	EPSD	TCGA;ICGC;COSMIC;GDSC;CCLE	31.796	Down-regulation
AGC_DMPK_ROCK_ROCK1_ST	O14950	MYL12B	Q13464	ROCK1	T19	R17C	17	Missense	proximal	-2	no	51.827	18.969	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	31.796	Loss
AGC_DMPK_ROCK_ROCK1_ST	O14950	MYL12B	Q13464	ROCK1	S20	R17C	17	Missense	distal	-3	no	40.125	14.840	PhosphoSitePlus;EPSD	TCGA;ICGC;COSMIC	31.796	Loss
AGC_DMPK_ROCK_ROCK1_ST	Q16555	DPYSL2	Q13464	ROCK1	S363	N356Y	356	Missense	distal	-7	no	35.420	35.456	EPSD	TCGA;COSMIC	31.796	Up-regulation
AGC_DMPK_ROCK_ROCK1_ST	Q16555	DPYSL2	Q13464	ROCK1	S363	V364I	364	Missense	proximal	1	no	35.420	35.165	EPSD	TCGA;COSMIC	31.796	Down-regulation
AGC_DMPK_ROCK_ROCK1_ST	Q16555	DPYSL2	Q13464	ROCK1	S427	A422T	422	Missense	distal	-5	no	33.068	32.507	EPSD	TCGA	31.796	Down-regulation
AGC_DMPK_ROCK_ROCK1_ST	Q16555	DPYSL2	Q13464	ROCK1	T555	P561S	561	Missense	distal	6	no	36.149	35.629	PhosphoSitePlus	TCGA;COSMIC	31.796	Down-regulation
AGC_DMPK_ROCK_ROCK1_ST	Q16555	DPYSL2	Q13464	ROCK1	T555	R553H	553	Missense	proximal	-2	no	36.149	25.013	PhosphoSitePlus	TCGA;COSMIC	31.796	Loss
AGC_DMPK_ROCK_ROCK1_ST	O14744	PRMT5	Q13464	ROCK1	S15	G11W	11	Missense	distal	-4	no	39.096	37.599	EPSD	TCGA;COSMIC	31.796	Down-regulation
AGC_DMPK_ROCK_ROCK1_ST	O14744	PRMT5	Q13464	ROCK1	S16	G11W	11	Missense	distal	-5	no	37.015	36.762	EPSD	TCGA;COSMIC	31.796	Down-regulation
AGC_DMPK_ROCK_ROCK1_ST	P24844	MYL9	Q13464	ROCK1	T10	K7R	7	Missense	distal	-3	no	31.749	35.460	EPSD	TCGA;ICGC;COSMIC	31.796	Gain
AGC_DMPK_ROCK_ROCK1_ST	P24844	MYL9	Q13464	ROCK1	T10	T11I	11	Missense	proximal	1	no	31.749	32.113	EPSD	TCGA;ICGC;COSMIC	31.796	Gain
AGC_DMPK_ROCK_ROCK1_ST	P24844	MYL9	Q13464	ROCK1	T10	R17W	17	Missense	distal	7	no	31.749	33.287	EPSD	TCGA;ICGC;COSMIC	31.796	Gain
AGC_DMPK_ROCK_ROCK1_ST	P24844	MYL9	Q13464	ROCK1	T10	T11S	11	Missense	proximal	1	no	31.749	32.334	EPSD	TCGA;ICGC	31.796	Gain
AGC_DMPK_ROCK_ROCK1_ST	P24844	MYL9	Q13464	ROCK1	T11	K7R	7	Missense	distal	-4	no	31.345	31.982	EPSD	TCGA;ICGC;COSMIC	31.796	Gain
AGC_DMPK_ROCK_ROCK1_ST	P24844	MYL9	Q13464	ROCK1	T11	R17W	17	Missense	distal	6	no	31.345	32.823	EPSD	TCGA;ICGC;COSMIC	31.796	Gain
AGC_DMPK_ROCK_ROCK1_ST	P24844	MYL9	Q13464	ROCK1	T19	R17W	17	Missense	proximal	-2	no	51.361	50.276	PhosphoSitePlus;EPSD	TCGA;ICGC;COSMIC	31.796	Down-regulation
AGC_DMPK_ROCK_ROCK1_ST	P24844	MYL9	Q13464	ROCK1	S20	R17W	17	Missense	distal	-3	no	39.387	30.226	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	31.796	Loss
AGC_DMPK_ROCK_ROCK1_ST	P24844	MYL9	Q13464	ROCK1	T135	E137K	137	Missense	proximal	2	no	30.919	34.590	EPSD	TCGA;COSMIC	31.796	Gain
AGC_DMPK_ROCK_ROCK1_ST	P07737	PFN1	Q13464	ROCK1	S58	S58R	58	Missense	central	0	yes	44.060	0.000	EPSD	TCGA;ICGC;COSMIC	31.796	Loss
AGC_DMPK_ROCK_ROCK1_ST	P07737	PFN1	Q13464	ROCK1	S72	L66R	66	Missense	distal	-6	no	30.354	36.249	EPSD	TCGA;ICGC	31.796	Gain
AGC_DMPK_ROCK_ROCK1_ST	P35611	ADD1	Q13464	ROCK1	S59	P65H	65	Missense	distal	6	no	34.118	33.729	EPSD	TCGA;ICGC;COSMIC	31.796	Down-regulation
AGC_DMPK_ROCK_ROCK1_ST	P35611	ADD1	Q13464	ROCK1	S133	S135F	135	Missense	proximal	2	no	40.124	38.348	EPSD	TCGA;ICGC;COSMIC	31.796	Down-regulation
AGC_DMPK_ROCK_ROCK1_ST	P35611	ADD1	Q13464	ROCK1	S133	D129N	129	Missense	distal	-4	no	40.124	40.486	EPSD	TCGA;ICGC	31.796	Up-regulation
AGC_DMPK_ROCK_ROCK1_ST	P35611	ADD1	Q13464	ROCK1	T445	L448P	448	Missense	distal	3	no	31.740	31.872	PhosphoSitePlus;EPSD	TCGA;ICGC;COSMIC	31.796	Gain
AGC_DMPK_ROCK_ROCK1_ST	P35611	ADD1	Q13464	ROCK1	T445	Q438R	438	Missense	distal	-7	no	31.740	31.823	PhosphoSitePlus;EPSD	TCGA;ICGC;COSMIC	31.796	Gain
AGC_DMPK_ROCK_ROCK1_ST	P26038	MSN	Q13464	ROCK1	T66	D69N	69	Missense	distal	3	no	36.764	36.843	EPSD	TCGA;ICGC;COSMIC	31.796	Up-regulation
AGC_DMPK_ROCK_ROCK1_ST	P26038	MSN	Q13464	ROCK1	T66	V65L	65	Missense	proximal	-1	no	36.764	36.247	EPSD	TCGA;ICGC;COSMIC	31.796	Down-regulation
AGC_DMPK_ROCK_ROCK1_ST	P26038	MSN	Q13464	ROCK1	T66	A67V	67	Missense	proximal	1	no	36.764	37.120	EPSD	TCGA;ICGC	31.796	Up-regulation
AGC_DMPK_ROCK_ROCK1_ST	P26038	MSN	Q13464	ROCK1	S74	D69N	69	Missense	distal	-5	no	33.231	33.998	EPSD	TCGA;ICGC;COSMIC	31.796	Up-regulation
AGC_DMPK_ROCK_ROCK1_ST	P26038	MSN	Q13464	ROCK1	S74	A67V	67	Missense	distal	-7	no	33.231	33.174	EPSD	TCGA;ICGC	31.796	Down-regulation
AGC_DMPK_ROCK_ROCK1_ST	P26038	MSN	Q13464	ROCK1	S144	H142R	142	Missense	proximal	-2	no	28.706	39.842	EPSD	TCGA;ICGC;COSMIC	31.796	Gain
AGC_DMPK_ROCK_ROCK1_ST	P26038	MSN	Q13464	ROCK1	S214	I208M	208	Missense	distal	-6	no	30.658	34.346	EPSD	TCGA;ICGC;COSMIC	31.796	Gain
AGC_DMPK_ROCK_ROCK1_ST	P26038	MSN	Q13464	ROCK1	S504	R503C	503	Missense	proximal	-1	no	36.774	32.493	EPSD	TCGA;ICGC;COSMIC	31.796	Down-regulation
AGC_DMPK_ROCK_ROCK1_ST	P26038	MSN	Q13464	ROCK1	S504	R508C	508	Missense	distal	4	no	36.774	35.588	EPSD	TCGA;ICGC;COSMIC	31.796	Down-regulation
AGC_DMPK_ROCK_ROCK1_ST	P26038	MSN	Q13464	ROCK1	S504	R503H	503	Missense	proximal	-1	no	36.774	34.205	EPSD	TCGA;ICGC;COSMIC	31.796	Down-regulation
AGC_DMPK_ROCK_ROCK1_ST	P26038	MSN	Q13464	ROCK1	S504	E505K	505	Missense	proximal	1	no	36.774	35.928	EPSD	TCGA;ICGC;COSMIC	31.796	Down-regulation
AGC_DMPK_ROCK_ROCK1_ST	P26038	MSN	Q13464	ROCK1	T510	E505K	505	Missense	distal	-5	no	30.773	32.878	EPSD	TCGA;ICGC;COSMIC	31.796	Gain
AGC_DMPK_ROCK_ROCK1_ST	P26038	MSN	Q13464	ROCK1	S536	D534Y	534	Missense	proximal	-2	no	28.846	36.536	EPSD	TCGA;ICGC;COSMIC	31.796	Gain
AGC_DMPK_ROCK_ROCK1_ST	P26038	MSN	Q13464	ROCK1	T558	R560C	560	Missense	proximal	2	no	34.154	31.640	PhosphoSitePlus	TCGA;ICGC;COSMIC	31.796	Loss
AGC_DMPK_ROCK_ROCK1_ST	P26038	MSN	Q13464	ROCK1	T558	Q561H	561	Missense	distal	3	no	34.154	34.240	PhosphoSitePlus	TCGA;ICGC;COSMIC	31.796	Up-regulation
AGC_DMPK_ROCK_ROCK1_ST	P26038	MSN	Q13464	ROCK1	T558	K557N	557	Missense	proximal	-1	no	34.154	31.784	PhosphoSitePlus	TCGA;ICGC	31.796	Loss
AGC_DMPK_ROCK_ROCK1_ST	P26038	MSN	Q13464	ROCK1	T558	R553Q	553	Missense	distal	-5	no	34.154	32.681	PhosphoSitePlus	TCGA;ICGC	31.796	Down-regulation
AGC_DMPK_ROCK_ROCK1_ST	P53671	LIMK2	Q13464	ROCK1	S318	I325V	325	Missense	distal	7	no	32.280	32.564	EPSD	TCGA;COSMIC;GDSC	31.796	Up-regulation
AGC_DMPK_ROCK_ROCK1_ST	O60237	PPP1R12B	Q13464	ROCK1	S29	P35S	35	Missense	distal	6	no	39.622	39.102	EPSD	TCGA;ICGC;COSMIC	31.796	Down-regulation
AGC_DMPK_ROCK_ROCK1_ST	O60237	PPP1R12B	Q13464	ROCK1	S420	P427L	427	Missense	distal	7	no	36.693	36.247	EPSD	TCGA;ICGC;COSMIC	31.796	Down-regulation
AGC_DMPK_ROCK_ROCK1_ST	O60237	PPP1R12B	Q13464	ROCK1	S420	F419L	419	Missense	proximal	-1	no	36.693	37.143	EPSD	TCGA	31.796	Up-regulation
AGC_DMPK_ROCK_ROCK1_ST	O60237	PPP1R12B	Q13464	ROCK1	S420	R417S	417	Missense	distal	-3	no	36.693	26.104	EPSD	TCGA;ICGC;COSMIC	31.796	Loss
AGC_DMPK_ROCK_ROCK1_ST	O60237	PPP1R12B	Q13464	ROCK1	S472	S472F	472	Missense	central	0	yes	36.366	0.000	EPSD	TCGA;ICGC;COSMIC	31.796	Loss
AGC_DMPK_ROCK_ROCK1_ST	O60237	PPP1R12B	Q13464	ROCK1	S472	Y469H	469	Missense	distal	-3	no	36.366	27.170	EPSD	TCGA;ICGC;COSMIC	31.796	Loss
AGC_DMPK_ROCK_ROCK1_ST	O60237	PPP1R12B	Q13464	ROCK1	S472	R476W	476	Missense	distal	4	no	36.366	34.915	EPSD	TCGA;ICGC;COSMIC	31.796	Down-regulation
AGC_DMPK_ROCK_ROCK1_ST	O60237	PPP1R12B	Q13464	ROCK1	S472	S471F	471	Missense	proximal	-1	no	36.366	33.163	EPSD	TCGA;ICGC;COSMIC	31.796	Down-regulation
AGC_DMPK_ROCK_ROCK1_ST	O60237	PPP1R12B	Q13464	ROCK1	S472	R470H	470	Missense	proximal	-2	no	36.366	25.231	EPSD	TCGA;ICGC;COSMIC	31.796	Loss
AGC_DMPK_ROCK_ROCK1_ST	O60237	PPP1R12B	Q13464	ROCK1	S473	S472F	472	Missense	proximal	-1	no	32.914	29.711	EPSD	TCGA;ICGC;COSMIC	31.796	Loss
AGC_DMPK_ROCK_ROCK1_ST	O60237	PPP1R12B	Q13464	ROCK1	S473	Y469H	469	Missense	distal	-4	no	32.914	32.770	EPSD	TCGA;ICGC;COSMIC	31.796	Down-regulation
AGC_DMPK_ROCK_ROCK1_ST	O60237	PPP1R12B	Q13464	ROCK1	S473	R476W	476	Missense	distal	3	no	32.914	32.732	EPSD	TCGA;ICGC;COSMIC	31.796	Down-regulation
AGC_DMPK_ROCK_ROCK1_ST	O60237	PPP1R12B	Q13464	ROCK1	S473	S471F	471	Missense	proximal	-2	no	32.914	34.468	EPSD	TCGA;ICGC;COSMIC	31.796	Up-regulation
AGC_DMPK_ROCK_ROCK1_ST	O60237	PPP1R12B	Q13464	ROCK1	S473	R470H	470	Missense	distal	-3	no	32.914	18.303	EPSD	TCGA;ICGC;COSMIC	31.796	Loss
AGC_DMPK_ROCK_ROCK1_ST	O60237	PPP1R12B	Q13464	ROCK1	S618	P622L	622	Missense	distal	4	no	37.825	36.809	EPSD	TCGA;ICGC;COSMIC	31.796	Down-regulation
AGC_DMPK_ROCK_ROCK1_ST	O60237	PPP1R12B	Q13464	ROCK1	T621	P622L	622	Missense	proximal	1	no	33.128	33.576	EPSD	TCGA;ICGC;COSMIC	31.796	Up-regulation
AGC_DMPK_ROCK_ROCK1_ST	O60237	PPP1R12B	Q13464	ROCK1	T621	E627G	627	Missense	distal	6	no	33.128	33.109	EPSD	TCGA;ICGC;COSMIC	31.796	Down-regulation
AGC_DMPK_ROCK_ROCK1_ST	O60237	PPP1R12B	Q13464	ROCK1	T642	S636C	636	Missense	distal	-6	no	35.241	28.814	EPSD	TCGA;ICGC;COSMIC	31.796	Loss
AGC_DMPK_ROCK_ROCK1_ST	O60237	PPP1R12B	Q13464	ROCK1	T642	G648A	648	Missense	distal	6	no	35.241	35.400	EPSD	TCGA;ICGC;COSMIC	31.796	Up-regulation
AGC_DMPK_ROCK_ROCK1_ST	O60237	PPP1R12B	Q13464	ROCK1	T642	R640Q	640	Missense	proximal	-2	no	35.241	22.070	EPSD	TCGA;ICGC;COSMIC	31.796	Loss
AGC_DMPK_ROCK_ROCK1_ST	O60237	PPP1R12B	Q13464	ROCK1	T642	R643Q	643	Missense	proximal	1	no	35.241	35.739	EPSD	TCGA;ICGC;COSMIC	31.796	Up-regulation
AGC_DMPK_ROCK_ROCK1_ST	O60237	PPP1R12B	Q13464	ROCK1	S645	G648A	648	Missense	distal	3	no	46.795	46.673	EPSD	TCGA;ICGC;COSMIC	31.796	Down-regulation
AGC_DMPK_ROCK_ROCK1_ST	O60237	PPP1R12B	Q13464	ROCK1	S645	R640Q	640	Missense	distal	-5	no	46.795	45.322	EPSD	TCGA;ICGC;COSMIC	31.796	Down-regulation
AGC_DMPK_ROCK_ROCK1_ST	O60237	PPP1R12B	Q13464	ROCK1	S645	R643Q	643	Missense	proximal	-2	no	46.795	33.625	EPSD	TCGA;ICGC;COSMIC	31.796	Down-regulation
AGC_DMPK_ROCK_ROCK1_ST	O60237	PPP1R12B	Q13464	ROCK1	T646	G648A	648	Missense	proximal	2	no	54.077	52.328	PhosphoSitePlus	TCGA;ICGC;COSMIC	31.796	Down-regulation
AGC_DMPK_ROCK_ROCK1_ST	O60237	PPP1R12B	Q13464	ROCK1	T646	R640Q	640	Missense	distal	-6	no	54.077	50.152	PhosphoSitePlus	TCGA;ICGC;COSMIC	31.796	Down-regulation
AGC_DMPK_ROCK_ROCK1_ST	O60237	PPP1R12B	Q13464	ROCK1	T646	R643Q	643	Missense	distal	-3	no	54.077	49.194	PhosphoSitePlus	TCGA;ICGC;COSMIC	31.796	Down-regulation
AGC_DMPK_ROCK_ROCK1_ST	O60237	PPP1R12B	Q13464	ROCK1	T650	G648A	648	Missense	proximal	-2	no	34.199	27.028	EPSD	TCGA;ICGC;COSMIC	31.796	Loss
AGC_DMPK_ROCK_ROCK1_ST	O60237	PPP1R12B	Q13464	ROCK1	T650	Q655H	655	Missense	distal	5	no	34.199	33.700	EPSD	TCGA;ICGC;COSMIC	31.796	Down-regulation
AGC_DMPK_ROCK_ROCK1_ST	O60237	PPP1R12B	Q13464	ROCK1	T650	R643Q	643	Missense	distal	-7	no	34.199	34.116	EPSD	TCGA;ICGC;COSMIC	31.796	Down-regulation
AGC_DMPK_ROCK_ROCK1_ST	O60237	PPP1R12B	Q13464	ROCK1	T808	F812L	812	Missense	distal	4	no	46.342	46.587	EPSD	TCGA;ICGC;COSMIC	31.796	Up-regulation
AGC_DMPK_ROCK_ROCK1_ST	O60237	PPP1R12B	Q13464	ROCK1	T808	R805Q	805	Missense	distal	-3	no	46.342	41.459	EPSD	TCGA;ICGC	31.796	Down-regulation
AGC_DMPK_ROCK_ROCK1_ST	O60237	PPP1R12B	Q13464	ROCK1	T808	N811H	811	Missense	distal	3	no	46.342	46.398	EPSD	TCGA;ICGC	31.796	Up-regulation
AGC_DMPK_ROCK_ROCK1_ST	O60237	PPP1R12B	Q13464	ROCK1	S855	S855L	855	Missense	central	0	yes	33.364	0.000	EPSD	TCGA;ICGC;COSMIC	31.796	Loss
AGC_DMPK_ROCK_ROCK1_ST	O60237	PPP1R12B	Q13464	ROCK1	S855	R859C	859	Missense	distal	4	no	33.364	32.179	EPSD	TCGA;ICGC;COSMIC;CCLE	31.796	Down-regulation
AGC_DMPK_ROCK_ROCK1_ST	O60237	PPP1R12B	Q13464	ROCK1	T869	A868D	868	Missense	proximal	-1	no	40.474	39.097	EPSD	TCGA	31.796	Down-regulation
AGC_DMPK_ROCK_ROCK1_ST	O60237	PPP1R12B	Q13464	ROCK1	T869	R873C	873	Missense	distal	4	no	40.474	39.289	EPSD	TCGA;ICGC;COSMIC	31.796	Down-regulation
AGC_DMPK_ROCK_ROCK1_ST	O60237	PPP1R12B	Q13464	ROCK1	T869	R866H	866	Missense	distal	-3	no	40.474	25.864	EPSD	TCGA;ICGC;COSMIC	31.796	Loss
AGC_DMPK_ROCK_ROCK1_ST	O60237	PPP1R12B	Q13464	ROCK1	T869	R873H	873	Missense	distal	4	no	40.474	39.886	EPSD	TCGA;ICGC;COSMIC	31.796	Down-regulation
AGC_DMPK_ROCK_ROCK1_ST	O60237	PPP1R12B	Q13464	ROCK1	S947	K954T	954	Missense	distal	7	no	34.156	35.461	EPSD	TCGA;ICGC;COSMIC	31.796	Up-regulation
AGC_DMPK_ROCK_ROCK1_ST	O43293	DAPK3	Q13464	ROCK1	S50	L49P	49	Missense	proximal	-1	no	48.189	48.923	EPSD	TCGA;ICGC;COSMIC	31.796	Up-regulation
AGC_DMPK_ROCK_ROCK1_ST	O43293	DAPK3	Q13464	ROCK1	S50	R47C	47	Missense	distal	-3	no	48.189	22.904	EPSD	TCGA;ICGC;COSMIC	31.796	Loss
AGC_DMPK_ROCK_ROCK1_ST	O43293	DAPK3	Q13464	ROCK1	S50	R48C	48	Missense	proximal	-2	no	48.189	15.331	EPSD	TCGA;ICGC;COSMIC	31.796	Loss
AGC_DMPK_ROCK_ROCK1_ST	O43293	DAPK3	Q13464	ROCK1	S50	R48H	48	Missense	proximal	-2	no	48.189	37.053	EPSD	TCGA;ICGC	31.796	Down-regulation
AGC_DMPK_ROCK_ROCK1_ST	O43293	DAPK3	Q13464	ROCK1	S50	S52I	52	Missense	proximal	2	no	48.189	46.061	EPSD	TCGA;ICGC;COSMIC	31.796	Down-regulation
AGC_DMPK_ROCK_ROCK1_ST	O43293	DAPK3	Q13464	ROCK1	S50	R53W	53	Missense	distal	3	no	48.189	48.007	EPSD	TCGA;ICGC;COSMIC	31.796	Down-regulation
AGC_DMPK_ROCK_ROCK1_ST	O43293	DAPK3	Q13464	ROCK1	S50	I44M	44	Missense	distal	-6	no	48.189	51.877	EPSD	TCGA;ICGC;COSMIC	31.796	Up-regulation
AGC_DMPK_ROCK_ROCK1_ST	O43293	DAPK3	Q13464	ROCK1	T265	D259Y	259	Missense	distal	-6	no	43.501	45.883	PhosphoSitePlus;EPSD	TCGA;ICGC;COSMIC	31.796	Up-regulation
AGC_DMPK_ROCK_ROCK1_ST	O43293	DAPK3	Q13464	ROCK1	T299	E304K	304	Missense	distal	5	no	35.827	35.122	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	31.796	Down-regulation
AGC_DMPK_ROCK_ROCK1_ST	O43293	DAPK3	Q13464	ROCK1	T300	E304K	304	Missense	distal	4	no	33.498	35.429	EPSD	TCGA;ICGC;COSMIC	31.796	Up-regulation
AGC_DMPK_ROCK_ROCK1_ST	O43293	DAPK3	Q13464	ROCK1	T306	E304K	304	Missense	proximal	-2	no	30.693	35.936	EPSD	TCGA;ICGC;COSMIC	31.796	Gain
AGC_DMPK_ROCK_ROCK1_ST	P08670	VIM	Q13464	ROCK1	S25	S22I	22	Missense	distal	-3	no	34.195	32.527	EPSD	TCGA;ICGC;COSMIC	31.796	Down-regulation
AGC_DMPK_ROCK_ROCK1_ST	P08670	VIM	Q13464	ROCK1	T32	T33M	33	Missense	proximal	1	no	37.377	37.902	EPSD	TCGA;ICGC;COSMIC	31.796	Up-regulation
AGC_DMPK_ROCK_ROCK1_ST	P08670	VIM	Q13464	ROCK1	T35	T33M	33	Missense	proximal	-2	no	28.132	33.642	EPSD	TCGA;ICGC;COSMIC	31.796	Gain
AGC_DMPK_ROCK_ROCK1_ST	P08670	VIM	Q13464	ROCK1	S39	T33M	33	Missense	distal	-6	no	31.411	32.184	EPSD	TCGA;ICGC;COSMIC	31.796	Gain
AGC_DMPK_ROCK_ROCK1_ST	P08670	VIM	Q13464	ROCK1	S47	R50H	50	Missense	distal	3	no	38.945	38.849	EPSD	TCGA;ICGC;COSMIC	31.796	Down-regulation
AGC_DMPK_ROCK_ROCK1_ST	P08670	VIM	Q13464	ROCK1	S55	P57R	57	Missense	proximal	2	no	30.076	32.208	EPSD	TCGA;ICGC;COSMIC	31.796	Gain
AGC_DMPK_ROCK_ROCK1_ST	P08670	VIM	Q13464	ROCK1	S66	R71W	71	Missense	distal	5	no	31.514	32.414	EPSD	TCGA;ICGC;COSMIC	31.796	Gain
AGC_DMPK_ROCK_ROCK1_ST	P08670	VIM	Q13464	ROCK1	S72	R71W	71	Missense	proximal	-1	no	36.246	34.293	PhosphoSitePlus	TCGA;ICGC;COSMIC	31.796	Down-regulation
AGC_DMPK_ROCK_ROCK1_ST	P08670	VIM	Q13464	ROCK1	S278	S278R	278	Missense	central	0	yes	40.007	0.000	EPSD	TCGA;ICGC;COSMIC	31.796	Loss
AGC_DMPK_ROCK_ROCK1_ST	P08670	VIM	Q13464	ROCK1	S278	N283D	283	Missense	distal	5	no	40.007	40.124	EPSD	TCGA;ICGC;COSMIC	31.796	Up-regulation
AGC_DMPK_ROCK_ROCK1_ST	P08670	VIM	Q13464	ROCK1	S325	A332S	332	Missense	distal	7	no	33.460	33.617	EPSD	TCGA;ICGC;COSMIC	31.796	Up-regulation
AGC_DMPK_ROCK_ROCK1_ST	P08670	VIM	Q13464	ROCK1	S325	R320Q	320	Missense	distal	-5	no	33.460	31.987	EPSD	TCGA;ICGC;COSMIC	31.796	Down-regulation
AGC_DMPK_ROCK_ROCK1_ST	P08670	VIM	Q13464	ROCK1	S325	L326F	326	Missense	proximal	1	no	33.460	33.428	EPSD	TCGA;ICGC;COSMIC	31.796	Down-regulation
AGC_DMPK_ROCK_ROCK1_ST	P08670	VIM	Q13464	ROCK1	S325	S325F	325	Missense	central	0	yes	33.460	0.000	EPSD	TCGA;ICGC;COSMIC	31.796	Loss
AGC_DMPK_ROCK_ROCK1_ST	P08670	VIM	Q13464	ROCK1	S325	Y319C	319	Missense	distal	-6	no	33.460	27.212	EPSD	TCGA;ICGC;COSMIC	31.796	Loss
AGC_DMPK_ROCK_ROCK1_ST	P08670	VIM	Q13464	ROCK1	S325	S325P	325	Missense	central	0	yes	33.460	0.000	EPSD	TCGA;ICGC;COSMIC;CCLE	31.796	Loss
AGC_DMPK_ROCK_ROCK1_ST	Q05397	PTK2	Q13464	ROCK1	S517	S517I	517	Missense	central	0	yes	36.405	0.000	EPSD	TCGA;ICGC;COSMIC	31.796	Loss
AGC_DMPK_ROCK_ROCK1_ST	Q05397	PTK2	Q13464	ROCK1	S517	S522Y	522	Missense	distal	5	no	36.405	36.413	EPSD	TCGA;ICGC;COSMIC	31.796	Up-regulation
AGC_DMPK_ROCK_ROCK1_ST	Q05397	PTK2	Q13464	ROCK1	S580	I586M	586	Missense	distal	6	no	38.069	38.426	EPSD	TCGA;ICGC;COSMIC	31.796	Up-regulation
AGC_DMPK_ROCK_ROCK1_ST	Q05397	PTK2	Q13464	ROCK1	S695	R696S	696	Missense	proximal	1	no	36.717	37.850	EPSD	TCGA;COSMIC	31.796	Up-regulation
AGC_DMPK_ROCK_ROCK1_ST	Q05397	PTK2	Q13464	ROCK1	S695	R690C	690	Missense	distal	-5	no	36.717	31.084	EPSD	TCGA;ICGC;COSMIC	31.796	Loss
AGC_DMPK_ROCK_ROCK1_ST	Q05397	PTK2	Q13464	ROCK1	S722	S725F	725	Missense	distal	3	no	36.463	36.329	EPSD	TCGA;ICGC	31.796	Down-regulation
AGC_DMPK_ROCK_ROCK1_ST	Q05397	PTK2	Q13464	ROCK1	S722	P718L	718	Missense	distal	-4	no	36.463	37.030	EPSD	TCGA;ICGC;COSMIC	31.796	Up-regulation
AGC_DMPK_ROCK_ROCK1_ST	Q05397	PTK2	Q13464	ROCK1	S722	P723L	723	Missense	proximal	1	no	36.463	36.911	EPSD	TCGA;ICGC;COSMIC	31.796	Up-regulation
AGC_DMPK_ROCK_ROCK1_ST	Q05397	PTK2	Q13464	ROCK1	S732	S725F	725	Missense	distal	-7	no	33.230	33.112	PhosphoSitePlus	TCGA;ICGC	31.796	Down-regulation
AGC_DMPK_ROCK_ROCK1_ST	Q05397	PTK2	Q13464	ROCK1	S840	R841Q	841	Missense	proximal	1	no	32.355	32.854	EPSD	TCGA;ICGC;COSMIC;GDSC	31.796	Up-regulation
AGC_DMPK_ROCK_ROCK1_ST	P53667	LIMK1	Q13464	ROCK1	S210	C208Y	208	Missense	proximal	-2	no	10.108	38.389	EPSD	TCGA;COSMIC	31.796	Gain
AGC_DMPK_ROCK_ROCK1_ST	P53667	LIMK1	Q13464	ROCK1	S439	A445T	445	Missense	distal	6	no	39.623	39.641	EPSD	TCGA;COSMIC	31.796	Up-regulation
AGC_DMPK_ROCK_ROCK1_ST	P53667	LIMK1	Q13464	ROCK1	T508	D502G	502	Missense	distal	-6	no	55.423	59.525	PhosphoSitePlus	TCGA;COSMIC	31.796	Up-regulation
AGC_DMPK_ROCK_ROCK1_ST	P53667	LIMK1	Q13464	ROCK1	T508	P513L	513	Missense	distal	5	no	55.423	55.656	PhosphoSitePlus	TCGA;COSMIC	31.796	Up-regulation
AGC_DMPK_ROCK_ROCK1_ST	P48436	SOX9	Q13464	ROCK1	S181	Y174C	174	Missense	distal	-7	no	49.170	49.093	PhosphoSitePlus	TCGA;ICGC;COSMIC	31.796	Down-regulation
AGC_DMPK_ROCK_ROCK1_ST	P48436	SOX9	Q13464	ROCK1	S181	P176S	176	Missense	distal	-5	no	49.170	50.843	PhosphoSitePlus	TCGA;ICGC;COSMIC	31.796	Up-regulation
AGC_DMPK_ROCK_ROCK1_ST	P48436	SOX9	Q13464	ROCK1	S181	Q175P	175	Missense	distal	-6	no	49.170	47.763	PhosphoSitePlus	TCGA;ICGC;COSMIC	31.796	Down-regulation
AGC_DMPK_ROCK_ROCK1_ST	P48436	SOX9	Q13464	ROCK1	S181	N184I	184	Missense	distal	3	no	49.170	49.108	PhosphoSitePlus	TCGA;ICGC;COSMIC	31.796	Down-regulation
AGC_DMPK_ROCK_ROCK1_ST	P48436	SOX9	Q13464	ROCK1	S181	R177W	177	Missense	distal	-4	no	49.170	44.884	PhosphoSitePlus	TCGA;ICGC;COSMIC	31.796	Down-regulation
AGC_DMPK_ROCK_ROCK1_ST	P48436	SOX9	Q13464	ROCK1	S181	Q186R	186	Missense	distal	5	no	49.170	48.330	PhosphoSitePlus	TCGA;ICGC	31.796	Down-regulation
AGC_DMPK_ROCK_ROCK1_ST	P48436	SOX9	Q13464	ROCK1	S181	A187V	187	Missense	distal	6	no	49.170	49.444	PhosphoSitePlus	TCGA;ICGC;COSMIC	31.796	Up-regulation
AGC_DMPK_ROCK_ROCK1_ST	O14974	PPP1R12A	Q13464	ROCK1	T443	R437M	437	Missense	distal	-6	no	37.502	36.435	EPSD	TCGA;ICGC;COSMIC	31.796	Down-regulation
AGC_DMPK_ROCK_ROCK1_ST	O14974	PPP1R12A	Q13464	ROCK1	T443	T443M	443	Missense	central	0	yes	37.502	0.000	EPSD	TCGA;ICGC;COSMIC	31.796	Loss
AGC_DMPK_ROCK_ROCK1_ST	O14974	PPP1R12A	Q13464	ROCK1	T443	W436C	436	Missense	distal	-7	no	37.502	37.494	EPSD	TCGA;ICGC;COSMIC	31.796	Down-regulation
AGC_DMPK_ROCK_ROCK1_ST	O14974	PPP1R12A	Q13464	ROCK1	S445	T443M	443	Missense	proximal	-2	no	26.623	32.133	EPSD	TCGA;ICGC;COSMIC	31.796	Gain
AGC_DMPK_ROCK_ROCK1_ST	O14974	PPP1R12A	Q13464	ROCK1	S525	R523Q	523	Missense	proximal	-2	no	35.425	22.255	EPSD	TCGA;GDSC	31.796	Loss
AGC_DMPK_ROCK_ROCK1_ST	O14974	PPP1R12A	Q13464	ROCK1	S668	R667I	667	Missense	proximal	-1	no	39.953	36.636	EPSD	TCGA;ICGC;COSMIC	31.796	Down-regulation
AGC_DMPK_ROCK_ROCK1_ST	O14974	PPP1R12A	Q13464	ROCK1	S692	R694T	694	Missense	proximal	2	no	35.655	35.241	EPSD	TCGA;COSMIC	31.796	Down-regulation
AGC_DMPK_ROCK_ROCK1_ST	O14974	PPP1R12A	Q13464	ROCK1	S695	R694T	694	Missense	proximal	-1	no	42.582	41.264	EPSD	TCGA;COSMIC	31.796	Down-regulation
AGC_DMPK_ROCK_ROCK1_ST	O14974	PPP1R12A	Q13464	ROCK1	S695	T700S	700	Missense	distal	5	no	42.582	42.879	EPSD	TCGA;ICGC;COSMIC	31.796	Up-regulation
AGC_DMPK_ROCK_ROCK1_ST	O14974	PPP1R12A	Q13464	ROCK1	T696	R694T	694	Missense	proximal	-2	no	53.165	39.891	EPSD;PhosphoSitePlus	TCGA;COSMIC	31.796	Down-regulation
AGC_DMPK_ROCK_ROCK1_ST	O14974	PPP1R12A	Q13464	ROCK1	T696	T700S	700	Missense	distal	4	no	53.165	53.145	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	31.796	Down-regulation
AGC_DMPK_ROCK_ROCK1_ST	O14974	PPP1R12A	Q13464	ROCK1	S852	R851K	851	Missense	proximal	-1	no	43.319	43.380	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	31.796	Up-regulation
AGC_DMPK_ROCK_ROCK1_ST	O14974	PPP1R12A	Q13464	ROCK1	S852	T853A	853	Missense	proximal	1	no	43.319	43.581	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	31.796	Up-regulation
AGC_DMPK_ROCK_ROCK1_ST	O14974	PPP1R12A	Q13464	ROCK1	S852	S852Y	852	Missense	central	0	yes	43.319	0.000	EPSD;PhosphoSitePlus	TCGA;ICGC	31.796	Loss
AGC_DMPK_ROCK_ROCK1_ST	O14974	PPP1R12A	Q13464	ROCK1	T853	R851K	851	Missense	proximal	-2	no	54.394	46.642	PhosphoSitePlus;EPSD	TCGA;ICGC;COSMIC	31.796	Down-regulation
AGC_DMPK_ROCK_ROCK1_ST	O14974	PPP1R12A	Q13464	ROCK1	T853	T853A	853	Missense	central	0	yes	54.394	0.000	PhosphoSitePlus;EPSD	TCGA;ICGC;COSMIC	31.796	Loss
AGC_DMPK_ROCK_ROCK1_ST	O14974	PPP1R12A	Q13464	ROCK1	T853	S852Y	852	Missense	proximal	-1	no	54.394	52.780	PhosphoSitePlus;EPSD	TCGA;ICGC	31.796	Down-regulation
AGC_DMPK_ROCK_ROCK1_ST	O14974	PPP1R12A	Q13464	ROCK1	S886	T884M	884	Missense	proximal	-2	no	27.426	32.936	EPSD	TCGA;ICGC;COSMIC	31.796	Gain
AGC_DMPK_ROCK_ROCK1_ST	O14974	PPP1R12A	Q13464	ROCK1	T892	E891K	891	Missense	proximal	-1	no	40.198	44.438	EPSD	TCGA;ICGC;COSMIC	31.796	Up-regulation
AGC_DMPK_ROCK_ROCK1_ST	O14974	PPP1R12A	Q13464	ROCK1	T892	S894Y	894	Missense	proximal	2	no	40.198	39.106	EPSD	TCGA;COSMIC	31.796	Down-regulation
AGC_DMPK_ROCK_ROCK1_ST	O14974	PPP1R12A	Q13464	ROCK1	S903	S903A	903	Missense	central	0	yes	33.551	0.000	EPSD	TCGA;ICGC;COSMIC	31.796	Loss
AGC_DMPK_ROCK_ROCK1_ST	O14974	PPP1R12A	Q13464	ROCK1	S903	R907C	907	Missense	distal	4	no	33.551	32.366	EPSD	TCGA;ICGC;COSMIC	31.796	Down-regulation
AGC_DMPK_ROCK_ROCK1_ST	Q9UPT6	MAPK8IP3	Q13464	ROCK1	T169	A163V	163	Missense	distal	-6	no	32.946	30.916	EPSD	TCGA;ICGC;COSMIC	31.796	Loss
AGC_DMPK_ROCK_ROCK1_ST	Q9UPT6	MAPK8IP3	Q13464	ROCK1	T169	H165Y	165	Missense	distal	-4	no	32.946	33.090	EPSD	TCGA;ICGC;COSMIC	31.796	Up-regulation
AGC_DMPK_ROCK_ROCK1_ST	Q9UPT6	MAPK8IP3	Q13464	ROCK1	T275	S282L	282	Missense	distal	7	no	35.212	34.985	EPSD	TCGA;ICGC;COSMIC;GDSC;CCLE	31.796	Down-regulation
AGC_DMPK_ROCK_ROCK1_ST	Q9UPT6	MAPK8IP3	Q13464	ROCK1	T275	S278F	278	Missense	distal	3	no	35.212	35.078	EPSD	TCGA;ICGC;COSMIC	31.796	Down-regulation
AGC_DMPK_ROCK_ROCK1_ST	Q9UPT6	MAPK8IP3	Q13464	ROCK1	S314	R309Q	309	Missense	distal	-5	no	41.971	40.498	PhosphoSitePlus;EPSD	TCGA;ICGC;COSMIC	31.796	Down-regulation
AGC_DMPK_ROCK_ROCK1_ST	Q9UPT6	MAPK8IP3	Q13464	ROCK1	S314	R309L	309	Missense	distal	-5	no	41.971	39.047	PhosphoSitePlus;EPSD	TCGA;ICGC;COSMIC	31.796	Down-regulation
AGC_DMPK_ROCK_ROCK1_ST	Q9UPT6	MAPK8IP3	Q13464	ROCK1	S314	D313N	313	Missense	proximal	-1	no	41.971	43.409	PhosphoSitePlus;EPSD	TCGA;ICGC;COSMIC	31.796	Up-regulation
AGC_DMPK_ROCK_ROCK1_ST	Q9UPT6	MAPK8IP3	Q13464	ROCK1	S364	R361C	361	Missense	distal	-3	no	37.309	12.024	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	31.796	Loss
AGC_DMPK_ROCK_ROCK1_ST	Q9UPT6	MAPK8IP3	Q13464	ROCK1	S364	R361L	361	Missense	distal	-3	no	37.309	25.837	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC;CCLE	31.796	Loss
AGC_DMPK_ROCK_ROCK1_ST	Q9UPT6	MAPK8IP3	Q13464	ROCK1	S364	G363R	363	Missense	proximal	-1	no	37.309	37.867	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	31.796	Up-regulation
AGC_DMPK_ROCK_ROCK1_ST	Q9UPT6	MAPK8IP3	Q13464	ROCK1	S364	R358H	358	Missense	distal	-6	no	37.309	33.790	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	31.796	Down-regulation
AGC_DMPK_ROCK_ROCK1_ST	Q9UPT6	MAPK8IP3	Q13464	ROCK1	S365	R361C	361	Missense	distal	-4	no	34.517	29.346	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	31.796	Loss
AGC_DMPK_ROCK_ROCK1_ST	Q9UPT6	MAPK8IP3	Q13464	ROCK1	S365	R361L	361	Missense	distal	-4	no	34.517	30.759	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC;CCLE	31.796	Loss
AGC_DMPK_ROCK_ROCK1_ST	Q9UPT6	MAPK8IP3	Q13464	ROCK1	S365	G363R	363	Missense	proximal	-2	no	34.517	44.273	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	31.796	Up-regulation
AGC_DMPK_ROCK_ROCK1_ST	Q9UPT6	MAPK8IP3	Q13464	ROCK1	S365	R358H	358	Missense	distal	-7	no	34.517	34.354	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	31.796	Down-regulation
AGC_DMPK_ROCK_ROCK1_ST	Q9UPT6	MAPK8IP3	Q13464	ROCK1	T367	G363R	363	Missense	distal	-4	no	29.183	31.973	EPSD	TCGA;ICGC;COSMIC	31.796	Gain
AGC_DMPK_ROCK_ROCK1_ST	Q9UPT6	MAPK8IP3	Q13464	ROCK1	T552	R550W	550	Missense	proximal	-2	no	38.740	37.654	EPSD	TCGA;COSMIC	31.796	Down-regulation
AGC_DMPK_ROCK_ROCK1_ST	Q9UPT6	MAPK8IP3	Q13464	ROCK1	S1191	E1196D	1196	Missense	distal	5	no	33.950	34.095	EPSD	TCGA;COSMIC	31.796	Up-regulation
AGC_DMPK_ROCK_ROCK1_ST	Q9UPT6	MAPK8IP3	Q13464	ROCK1	S1191	G1195R	1195	Missense	distal	4	no	33.950	34.381	EPSD	TCGA;COSMIC	31.796	Up-regulation
AGC_PKG_PRKG2_ST	P29474	NOS3	Q13237	PRKG2	S57	P55L	55	Missense	proximal	-2	no	27.585	44.565	EPSD	TCGA;ICGC;COSMIC	42.682	Gain
AGC_PKG_PRKG2_ST	P29474	NOS3	Q13237	PRKG2	S114	P118L	118	Missense	distal	4	no	57.772	53.857	EPSD	TCGA;ICGC;COSMIC	42.682	Down-regulation
AGC_PKG_PRKG2_ST	P29474	NOS3	Q13237	PRKG2	T495	T488A	488	Missense	distal	-7	no	68.880	67.351	PhosphoSitePlus;EPSD	TCGA;ICGC;COSMIC	42.682	Down-regulation
AGC_PKG_PRKG2_ST	P29474	NOS3	Q13237	PRKG2	S615	R612C	612	Missense	distal	-3	no	44.807	6.283	EPSD	TCGA;ICGC;COSMIC	42.682	Loss
AGC_PKG_PRKG2_ST	P29474	NOS3	Q13237	PRKG2	S615	S617F	617	Missense	proximal	2	no	44.807	44.980	EPSD	TCGA;ICGC;COSMIC;GDSC	42.682	Up-regulation
AGC_PKG_PRKG2_ST	P29474	NOS3	Q13237	PRKG2	S615	R612H	612	Missense	distal	-3	no	44.807	30.991	EPSD	TCGA;ICGC;COSMIC	42.682	Loss
AGC_PKG_PRKG2_ST	P29474	NOS3	Q13237	PRKG2	S633	G640V	640	Missense	distal	7	no	74.934	75.421	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	42.682	Up-regulation
AGC_PKG_PRKG2_ST	P29474	NOS3	Q13237	PRKG2	S1177	R1172H	1172	Missense	distal	-5	no	74.260	74.286	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC;GDSC;CCLE	42.682	Up-regulation
AGC_PKG_PRKG2_ST	P29474	NOS3	Q13237	PRKG2	S1177	E1182A	1182	Missense	distal	5	no	74.260	74.342	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	42.682	Up-regulation
AGC_PKG_PRKG2_ST	P29474	NOS3	Q13237	PRKG2	S1177	R1183C	1183	Missense	distal	6	no	74.260	74.492	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	42.682	Up-regulation
AGC_PKG_PRKG2_ST	P29474	NOS3	Q13237	PRKG2	S1177	R1174H	1174	Missense	distal	-3	no	74.260	60.443	EPSD;PhosphoSitePlus	TCGA;ICGC	42.682	Down-regulation
AGC_PKG_PRKG2_ST	P04626	ERBB2	Q13237	PRKG2	T686	R688Q	688	Missense	proximal	2	no	64.945	65.088	PhosphoSitePlus	TCGA;COSMIC	42.682	Up-regulation
AGC_PKG_PRKG2_ST	P04626	ERBB2	Q13237	PRKG2	T686	T686M	686	Missense	central	0	yes	64.945	0.000	PhosphoSitePlus	TCGA;COSMIC	42.682	Loss
AGC_PKG_PRKG2_ST	P04626	ERBB2	Q13237	PRKG2	T759	L755M	755	Missense	distal	-4	no	42.419	42.917	EPSD	TCGA;COSMIC	42.682	Gain
AGC_PKG_PRKG2_ST	P04626	ERBB2	Q13237	PRKG2	T759	L755W	755	Missense	distal	-4	no	42.419	42.810	EPSD	TCGA;COSMIC	42.682	Gain
AGC_PKG_PRKG2_ST	P04626	ERBB2	Q13237	PRKG2	S819	D821H	821	Missense	proximal	2	no	49.056	49.247	EPSD	TCGA;COSMIC	42.682	Up-regulation
AGC_PKG_PRKG2_ST	P04626	ERBB2	Q13237	PRKG2	S819	R814H	814	Missense	distal	-5	no	49.056	49.083	EPSD	TCGA;COSMIC	42.682	Up-regulation
AGC_PKG_PRKG2_ST	P04626	ERBB2	Q13237	PRKG2	T900	R897Q	897	Missense	distal	-3	no	58.632	42.428	EPSD	TCGA;COSMIC	42.682	Loss
AGC_PKG_PRKG2_ST	P04626	ERBB2	Q13237	PRKG2	S1050	G1057V	1057	Missense	distal	7	no	61.015	61.503	EPSD	TCGA;COSMIC	42.682	Up-regulation
AGC_PKG_PRKG2_ST	P04626	ERBB2	Q13237	PRKG2	S1051	G1057V	1057	Missense	distal	6	no	44.772	44.802	EPSD	TCGA;COSMIC	42.682	Up-regulation
AGC_PKG_PRKG2_ST	P04626	ERBB2	Q13237	PRKG2	S1054	G1057V	1057	Missense	distal	3	no	49.219	49.513	EPSD	TCGA;COSMIC	42.682	Up-regulation
AGC_PKG_PRKG2_ST	P04626	ERBB2	Q13237	PRKG2	S1113	R1111W	1111	Missense	proximal	-2	no	57.408	24.058	EPSD	TCGA;COSMIC	42.682	Loss
AGC_PKG_PRKG2_ST	P29350	PTPN6	Q13237	PRKG2	S10	S10N	10	Missense	central	0	yes	48.068	0.000	EPSD	TCGA;COSMIC	42.682	Loss
AGC_PKG_PRKG2_ST	P29350	PTPN6	Q13237	PRKG2	S32	R30Q	30	Missense	proximal	-2	no	62.940	47.926	EPSD	TCGA;COSMIC	42.682	Down-regulation
AGC_PKG_PRKG2_ST	P29350	PTPN6	Q13237	PRKG2	T462	R459H	459	Missense	distal	-3	no	43.545	29.729	EPSD	TCGA;COSMIC	42.682	Loss
AGC_PKG_PRKG2_ST	P29350	PTPN6	Q13237	PRKG2	S553	S556L	556	Missense	distal	3	no	84.676	83.810	EPSD;PhosphoSitePlus	TCGA	42.682	Down-regulation
AGC_PKG_PRKG2_ST	P29350	PTPN6	Q13237	PRKG2	S553	S553P	553	Missense	central	0	yes	84.676	0.000	EPSD;PhosphoSitePlus	TCGA;COSMIC	42.682	Loss
AGC_PKG_PRKG2_ST	P29350	PTPN6	Q13237	PRKG2	S556	E561Q	561	Missense	distal	5	no	50.092	49.811	PhosphoSitePlus;EPSD	TCGA;ICGC;COSMIC	42.682	Down-regulation
AGC_PKG_PRKG2_ST	P29350	PTPN6	Q13237	PRKG2	S556	S556L	556	Missense	central	0	yes	50.092	0.000	PhosphoSitePlus;EPSD	TCGA	42.682	Loss
AGC_PKG_PRKG2_ST	P29350	PTPN6	Q13237	PRKG2	S556	S553P	553	Missense	distal	-3	no	50.092	42.744	PhosphoSitePlus;EPSD	TCGA;COSMIC	42.682	Down-regulation
AGC_PKG_PRKG2_ST	P29350	PTPN6	Q13237	PRKG2	S557	E561Q	561	Missense	distal	4	no	48.590	46.071	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	42.682	Down-regulation
AGC_PKG_PRKG2_ST	P29350	PTPN6	Q13237	PRKG2	S557	S556L	556	Missense	proximal	-1	no	48.590	48.234	EPSD;PhosphoSitePlus	TCGA	42.682	Down-regulation
AGC_PKG_PRKG2_ST	P29350	PTPN6	Q13237	PRKG2	S557	S553P	553	Missense	distal	-4	no	48.590	49.705	EPSD;PhosphoSitePlus	TCGA;COSMIC	42.682	Up-regulation
AGC_PKG_PRKG2_ST	P09619	PDGFRB	Q13237	PRKG2	S643	S642N	642	Missense	proximal	-1	no	63.535	63.995	EPSD	TCGA;ICGC;COSMIC	42.682	Up-regulation
AGC_PKG_PRKG2_ST	P09619	PDGFRB	Q13237	PRKG2	S643	S650L	650	Missense	distal	7	no	63.535	61.615	EPSD	TCGA;ICGC;COSMIC	42.682	Down-regulation
AGC_PKG_PRKG2_ST	P09619	PDGFRB	Q13237	PRKG2	S643	L648F	648	Missense	distal	5	no	63.535	63.553	EPSD	TCGA;ICGC;COSMIC	42.682	Up-regulation
AGC_PKG_PRKG2_ST	P09619	PDGFRB	Q13237	PRKG2	S643	R641C	641	Missense	proximal	-2	no	63.535	29.443	EPSD	TCGA;ICGC;COSMIC	42.682	Loss
AGC_PKG_PRKG2_ST	P09619	PDGFRB	Q13237	PRKG2	S705	R708C	708	Missense	distal	3	no	53.834	53.748	EPSD	TCGA;ICGC;COSMIC	42.682	Down-regulation
AGC_PKG_PRKG2_ST	P09619	PDGFRB	Q13237	PRKG2	S705	R709L	709	Missense	distal	4	no	53.834	52.294	EPSD	TCGA;ICGC;COSMIC	42.682	Down-regulation
AGC_PKG_PRKG2_ST	P09619	PDGFRB	Q13237	PRKG2	S705	P711H	711	Missense	distal	6	no	53.834	54.691	EPSD	TCGA;ICGC;COSMIC	42.682	Up-regulation
AGC_PKG_PRKG2_ST	P09619	PDGFRB	Q13237	PRKG2	S705	R708L	708	Missense	distal	3	no	53.834	53.433	EPSD	TCGA;ICGC;COSMIC	42.682	Down-regulation
AGC_PKG_PRKG2_ST	P09619	PDGFRB	Q13237	PRKG2	S748	Y751C	751	Missense	distal	3	no	46.193	46.215	EPSD	TCGA;ICGC;COSMIC	42.682	Up-regulation
AGC_PKG_PRKG2_ST	Q14847	LASP1	Q13237	PRKG2	S61	V65L	65	Missense	distal	4	no	45.490	42.239	EPSD	TCGA;ICGC;COSMIC	42.682	Loss
AGC_PKG_PRKG2_ST	Q14847	LASP1	Q13237	PRKG2	S61	A55V	55	Missense	distal	-6	no	45.490	43.511	EPSD	TCGA;COSMIC	42.682	Down-regulation
AGC_PKG_PRKG2_ST	Q14847	LASP1	Q13237	PRKG2	S146	M139V	139	Missense	distal	-7	no	70.509	68.972	PhosphoSitePlus	TCGA;ICGC;COSMIC	42.682	Down-regulation
AGC_PKG_PRKG2_ST	P32929	CTH	Q13237	PRKG2	S377	E383Q	383	Missense	distal	6	no	68.731	69.220	PhosphoSitePlus	TCGA;ICGC;COSMIC	42.682	Up-regulation
AGC_PKG_PRKG2_ST	P32929	CTH	Q13237	PRKG2	S377	E381Q	381	Missense	distal	4	no	68.731	66.212	PhosphoSitePlus	TCGA	42.682	Down-regulation
AGC_PKG_PRKG2_ST	P32929	CTH	Q13237	PRKG2	S377	R375Q	375	Missense	proximal	-2	no	68.731	53.717	PhosphoSitePlus	TCGA;ICGC;COSMIC	42.682	Down-regulation
AGC_PKG_PRKG2_ST	P08581	MET	Q13237	PRKG2	S441	I446V	446	Missense	distal	5	no	48.721	49.120	EPSD	TCGA;ICGC;COSMIC	42.682	Up-regulation
AGC_PKG_PRKG2_ST	P08581	MET	Q13237	PRKG2	S441	S441C	441	Missense	central	0	yes	48.721	0.000	EPSD	TCGA;ICGC;COSMIC	42.682	Loss
AGC_PKG_PRKG2_ST	P08581	MET	Q13237	PRKG2	S441	T440I	440	Missense	proximal	-1	no	48.721	47.685	EPSD	TCGA;ICGC	42.682	Down-regulation
AGC_PKG_PRKG2_ST	P08581	MET	Q13237	PRKG2	S441	S441Y	441	Missense	central	0	yes	48.721	0.000	EPSD	TCGA;ICGC;COSMIC	42.682	Loss
AGC_PKG_PRKG2_ST	P08581	MET	Q13237	PRKG2	S441	E436K	436	Missense	distal	-5	no	48.721	48.689	EPSD	TCGA;ICGC;COSMIC	42.682	Down-regulation
AGC_PKG_PRKG2_ST	P08581	MET	Q13237	PRKG2	S637	F634L	634	Missense	distal	-3	no	33.785	42.866	EPSD	TCGA;COSMIC	42.682	Gain
AGC_PKG_PRKG2_ST	P08581	MET	Q13237	PRKG2	S637	F634S	634	Missense	distal	-3	no	33.785	49.540	EPSD	TCGA;ICGC;COSMIC	42.682	Gain
AGC_PKG_PRKG2_ST	P08581	MET	Q13237	PRKG2	S758	S752Y	752	Missense	distal	-6	no	44.324	41.541	EPSD	TCGA;ICGC;CCLE	42.682	Loss
AGC_PKG_PRKG2_ST	P08581	MET	Q13237	PRKG2	S758	K751I	751	Missense	distal	-7	no	44.324	46.777	EPSD	TCGA;ICGC;COSMIC	42.682	Up-regulation
AGC_PKG_PRKG2_ST	P08581	MET	Q13237	PRKG2	S1020	R1022Q	1022	Missense	proximal	2	no	50.309	50.451	EPSD	TCGA;COSMIC	42.682	Up-regulation
AGC_PKG_PRKG2_ST	P08581	MET	Q13237	PRKG2	S1338	E1332G	1332	Missense	distal	-6	no	57.530	56.800	EPSD	TCGA;COSMIC	42.682	Down-regulation
TK_Fer_FER_Y	Q16555	DPYSL2	P16591	FER	Y479	S486N	486	Missense	distal	7	no	0.174	0.163	EPSD;PhosphoSitePlus	TCGA	0.101	Down-regulation
TK_Fer_FER_Y	P15311	EZR	P16591	FER	Y354	K359N	359	Missense	distal	5	no	0.173	0.179	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	0.101	Up-regulation
TK_Fer_FER_Y	P15311	EZR	P16591	FER	Y354	D353N	353	Missense	proximal	-1	no	0.173	0.166	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	0.101	Down-regulation
TK_Fer_FER_Y	P15311	EZR	P16591	FER	Y478	P480Q	480	Missense	proximal	2	no	0.203	0.215	PhosphoSitePlus;EPSD	TCGA;ICGC;COSMIC	0.101	Up-regulation
TK_Fer_FER_Y	P15311	EZR	P16591	FER	Y483	P480Q	480	Missense	distal	-3	no	0.131	0.139	EPSD	TCGA;ICGC;COSMIC	0.101	Up-regulation
TK_Fer_FER_Y	P10275	AR	P16591	FER	Y225	K222N	222	Missense	distal	-3	no	0.181	0.180	PhosphoSitePlus	TCGA;ICGC;COSMIC	0.101	Down-regulation
TK_Fer_FER_Y	P40763	STAT3	P16591	FER	Y674	P678L	678	Missense	distal	4	no	0.132	0.130	EPSD	TCGA;ICGC;COSMIC	0.101	Down-regulation
TK_Fer_FER_Y	P40763	STAT3	P16591	FER	Y674	P678S	678	Missense	distal	4	no	0.132	0.146	EPSD	TCGA;ICGC;COSMIC	0.101	Up-regulation
TK_Fer_FER_Y	P40763	STAT3	P16591	FER	Y674	P675S	675	Missense	proximal	1	no	0.132	0.167	EPSD	TCGA;ICGC;COSMIC	0.101	Up-regulation
TK_Fer_FER_Y	P40763	STAT3	P16591	FER	Y674	K679N	679	Missense	distal	5	no	0.132	0.138	EPSD	TCGA;ICGC	0.101	Up-regulation
TK_Fer_FER_Y	P16591	FER	P16591	FER	Y229	G224C	224	Missense	distal	-5	no	0.133	0.130	EPSD	TCGA;COSMIC	0.101	Down-regulation
TK_Fer_FER_Y	P16591	FER	P16591	FER	Y229	S234N	234	Missense	distal	5	no	0.133	0.139	EPSD	TCGA;COSMIC	0.101	Up-regulation
TK_Fer_FER_Y	P16591	FER	P16591	FER	Y615	A609V	609	Missense	distal	-6	no	0.186	0.184	EPSD;PhosphoSitePlus	TCGA;COSMIC	0.101	Down-regulation
TK_Fer_FER_Y	P16591	FER	P16591	FER	Y615	L612F	612	Missense	distal	-3	no	0.186	0.183	EPSD;PhosphoSitePlus	TCGA;COSMIC	0.101	Down-regulation
TK_Fer_FER_Y	P16591	FER	P16591	FER	Y615	Y615C	615	Missense	central	0	yes	0.186	0.000	EPSD;PhosphoSitePlus	TCGA;COSMIC	0.101	Loss
TK_Fer_FER_Y	P16591	FER	P16591	FER	Y714	R707H	707	Missense	distal	-7	no	0.205	0.199	PhosphoSitePlus;EPSD	TCGA;ICGC;COSMIC	0.101	Down-regulation
TK_Fer_FER_Y	P16591	FER	P16591	FER	Y714	E709G	709	Missense	distal	-5	no	0.205	0.238	PhosphoSitePlus;EPSD	TCGA;COSMIC	0.101	Up-regulation
TK_Fer_FER_Y	P16591	FER	P16591	FER	Y714	S716Y	716	Missense	proximal	2	no	0.205	0.193	PhosphoSitePlus;EPSD	TCGA	0.101	Down-regulation
TK_Fer_FER_Y	P14923	JUP	P16591	FER	Y133	E138K	138	Missense	distal	5	no	0.147	0.144	EPSD	TCGA;ICGC;COSMIC	0.101	Down-regulation
TK_Fer_FER_Y	P14923	JUP	P16591	FER	Y133	D136N	136	Missense	distal	3	no	0.147	0.145	EPSD	TCGA;ICGC	0.101	Down-regulation
TK_Fer_FER_Y	P14923	JUP	P16591	FER	Y550	Q548L	548	Missense	proximal	-2	no	0.211	0.209	PhosphoSitePlus	TCGA;ICGC;COSMIC	0.101	Down-regulation
TK_Fer_FER_Y	P14923	JUP	P16591	FER	Y550	T551M	551	Missense	proximal	1	no	0.211	0.185	PhosphoSitePlus	TCGA;ICGC;COSMIC;GDSC	0.101	Down-regulation
TK_Fer_FER_Y	P14923	JUP	P16591	FER	Y550	G545C	545	Missense	distal	-5	no	0.211	0.208	PhosphoSitePlus	TCGA;ICGC;COSMIC	0.101	Down-regulation
CMGC_CDK_CDK9_CDK9_ST	O00267	SUPT5H	P50750	CDK9	S108	E104K	104	Missense	distal	-4	no	2.024	2.038	EPSD	TCGA;ICGC;COSMIC	1.932	Up-regulation
CMGC_CDK_CDK9_CDK9_ST	O00267	SUPT5H	P50750	CDK9	S108	D111N	111	Missense	distal	3	no	2.024	2.175	EPSD	TCGA;ICGC;COSMIC	1.932	Up-regulation
CMGC_CDK_CDK9_CDK9_ST	O00267	SUPT5H	P50750	CDK9	T208	S214L	214	Missense	distal	6	no	5.170	4.533	EPSD	TCGA;ICGC;COSMIC	1.932	Down-regulation
CMGC_CDK_CDK9_CDK9_ST	O00267	SUPT5H	P50750	CDK9	T208	T206R	206	Missense	proximal	-2	no	5.170	5.105	EPSD	TCGA;ICGC	1.932	Down-regulation
CMGC_CDK_CDK9_CDK9_ST	O00267	SUPT5H	P50750	CDK9	T208	A202T	202	Missense	distal	-6	no	5.170	5.331	EPSD	TCGA;ICGC;COSMIC	1.932	Up-regulation
CMGC_CDK_CDK9_CDK9_ST	O00267	SUPT5H	P50750	CDK9	T655	V654M	654	Missense	proximal	-1	no	2.325	2.338	EPSD	TCGA;ICGC;COSMIC	1.932	Up-regulation
CMGC_CDK_CDK9_CDK9_ST	O00267	SUPT5H	P50750	CDK9	S666	I669T	669	Missense	distal	3	no	6.182	6.269	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	1.932	Up-regulation
CMGC_CDK_CDK9_CDK9_ST	O00267	SUPT5H	P50750	CDK9	S666	A663T	663	Missense	distal	-3	no	6.182	6.149	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	1.932	Down-regulation
CMGC_CDK_CDK9_CDK9_ST	O00267	SUPT5H	P50750	CDK9	S671	A677D	677	Missense	distal	6	no	5.138	5.085	EPSD	TCGA;ICGC	1.932	Down-regulation
CMGC_CDK_CDK9_CDK9_ST	O00267	SUPT5H	P50750	CDK9	S671	I669T	669	Missense	proximal	-2	no	5.138	5.368	EPSD	TCGA;ICGC;COSMIC	1.932	Up-regulation
CMGC_CDK_CDK9_CDK9_ST	O00267	SUPT5H	P50750	CDK9	S686	F684C	684	Missense	proximal	-2	no	4.609	4.603	EPSD	TCGA;ICGC;COSMIC	1.932	Down-regulation
CMGC_CDK_CDK9_CDK9_ST	O00267	SUPT5H	P50750	CDK9	T768	Y765C	765	Missense	distal	-3	no	5.825	5.835	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	1.932	Up-regulation
CMGC_CDK_CDK9_CDK9_ST	O00267	SUPT5H	P50750	CDK9	T768	T775M	775	Missense	distal	7	no	5.825	5.872	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	1.932	Up-regulation
CMGC_CDK_CDK9_CDK9_ST	O00267	SUPT5H	P50750	CDK9	T768	T762I	762	Missense	distal	-6	no	5.825	5.654	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	1.932	Down-regulation
CMGC_CDK_CDK9_CDK9_ST	O00267	SUPT5H	P50750	CDK9	T775	T775M	775	Missense	central	0	yes	5.410	0.000	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	1.932	Loss
CMGC_CDK_CDK9_CDK9_ST	O00267	SUPT5H	P50750	CDK9	T791	D795Y	795	Missense	distal	4	no	6.618	6.627	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	1.932	Up-regulation
CMGC_CDK_CDK9_CDK9_ST	O00267	SUPT5H	P50750	CDK9	T791	G796D	796	Missense	distal	5	no	6.618	6.501	EPSD;PhosphoSitePlus	TCGA;ICGC	1.932	Down-regulation
CMGC_CDK_CDK9_CDK9_ST	O00267	SUPT5H	P50750	CDK9	T799	D795Y	795	Missense	distal	-4	no	4.553	4.562	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	1.932	Up-regulation
CMGC_CDK_CDK9_CDK9_ST	O00267	SUPT5H	P50750	CDK9	T799	G796D	796	Missense	distal	-3	no	4.553	4.554	EPSD;PhosphoSitePlus	TCGA;ICGC	1.932	Up-regulation
CMGC_CDK_CDK9_CDK9_ST	O00267	SUPT5H	P50750	CDK9	T806	R813H	813	Missense	distal	7	no	5.999	6.022	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC;CCLE	1.932	Up-regulation
CMGC_CDK_CDK9_CDK9_ST	O00267	SUPT5H	P50750	CDK9	T806	S812C	812	Missense	distal	6	no	5.999	5.328	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	1.932	Down-regulation
CMGC_CDK_CDK9_CDK9_ST	O00267	SUPT5H	P50750	CDK9	T806	S812N	812	Missense	distal	6	no	5.999	5.750	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	1.932	Down-regulation
CMGC_CDK_CDK9_CDK9_ST	O00267	SUPT5H	P50750	CDK9	S812	R813H	813	Missense	proximal	1	no	2.029	1.631	EPSD	TCGA;ICGC;COSMIC;CCLE	1.932	Loss
CMGC_CDK_CDK9_CDK9_ST	O00267	SUPT5H	P50750	CDK9	S812	Q817H	817	Missense	distal	5	no	2.029	1.815	EPSD	TCGA;ICGC;COSMIC	1.932	Loss
CMGC_CDK_CDK9_CDK9_ST	O00267	SUPT5H	P50750	CDK9	S812	Q817K	817	Missense	distal	5	no	2.029	1.886	EPSD	TCGA;ICGC;COSMIC	1.932	Loss
CMGC_CDK_CDK9_CDK9_ST	O00267	SUPT5H	P50750	CDK9	S812	S812C	812	Missense	central	0	yes	2.029	0.000	EPSD	TCGA;ICGC;COSMIC	1.932	Loss
CMGC_CDK_CDK9_CDK9_ST	O00267	SUPT5H	P50750	CDK9	S812	S812N	812	Missense	central	0	yes	2.029	0.000	EPSD	TCGA;ICGC;COSMIC	1.932	Loss
CMGC_CDK_CDK9_CDK9_ST	O00267	SUPT5H	P50750	CDK9	T814	R813H	813	Missense	proximal	-1	no	6.210	6.205	PhosphoSitePlus;EPSD	TCGA;ICGC;COSMIC;CCLE	1.932	Down-regulation
CMGC_CDK_CDK9_CDK9_ST	O00267	SUPT5H	P50750	CDK9	T814	Q817H	817	Missense	distal	3	no	6.210	6.077	PhosphoSitePlus;EPSD	TCGA;ICGC;COSMIC	1.932	Down-regulation
CMGC_CDK_CDK9_CDK9_ST	O00267	SUPT5H	P50750	CDK9	T814	Q817K	817	Missense	distal	3	no	6.210	6.127	PhosphoSitePlus;EPSD	TCGA;ICGC;COSMIC	1.932	Down-regulation
CMGC_CDK_CDK9_CDK9_ST	O00267	SUPT5H	P50750	CDK9	T814	S812C	812	Missense	proximal	-2	no	6.210	5.684	PhosphoSitePlus;EPSD	TCGA;ICGC;COSMIC	1.932	Down-regulation
CMGC_CDK_CDK9_CDK9_ST	O00267	SUPT5H	P50750	CDK9	T814	S812N	812	Missense	proximal	-2	no	6.210	6.084	PhosphoSitePlus;EPSD	TCGA;ICGC;COSMIC	1.932	Down-regulation
CMGC_CDK_CDK9_CDK9_ST	O00267	SUPT5H	P50750	CDK9	S867	N871K	871	Missense	distal	4	no	5.181	5.159	EPSD	TCGA;ICGC;COSMIC	1.932	Down-regulation
CMGC_CDK_CDK9_CDK9_ST	O00267	SUPT5H	P50750	CDK9	T878	P882L	882	Missense	distal	4	no	4.472	4.430	EPSD	TCGA;ICGC;COSMIC	1.932	Down-regulation
CMGC_CDK_CDK9_CDK9_ST	O00267	SUPT5H	P50750	CDK9	T878	Y885H	885	Missense	distal	7	no	4.472	4.434	EPSD	TCGA;ICGC;COSMIC	1.932	Down-regulation
CMGC_CDK_CDK9_CDK9_ST	O00267	SUPT5H	P50750	CDK9	T878	N871K	871	Missense	distal	-7	no	4.472	4.483	EPSD	TCGA;ICGC;COSMIC	1.932	Up-regulation
CMGC_CDK_CDK9_CDK9_ST	O00267	SUPT5H	P50750	CDK9	T878	P882Q	882	Missense	distal	4	no	4.472	4.502	EPSD	TCGA;ICGC;COSMIC	1.932	Up-regulation
CMGC_CDK_CDK9_CDK9_ST	O00267	SUPT5H	P50750	CDK9	T881	P882L	882	Missense	proximal	1	no	4.187	-1.411	EPSD	TCGA;ICGC;COSMIC	1.932	Loss
CMGC_CDK_CDK9_CDK9_ST	O00267	SUPT5H	P50750	CDK9	T881	Y885H	885	Missense	distal	4	no	4.187	4.200	EPSD	TCGA;ICGC;COSMIC	1.932	Up-regulation
CMGC_CDK_CDK9_CDK9_ST	O00267	SUPT5H	P50750	CDK9	T881	P882Q	882	Missense	proximal	1	no	4.187	0.632	EPSD	TCGA;ICGC;COSMIC	1.932	Loss
CMGC_CDK_CDK9_CDK9_ST	O00267	SUPT5H	P50750	CDK9	S897	S891F	891	Missense	distal	-6	no	4.658	4.220	EPSD	TCGA;ICGC;COSMIC	1.932	Down-regulation
CMGC_CDK_CDK9_CDK9_ST	O00267	SUPT5H	P50750	CDK9	S897	F890L	890	Missense	distal	-7	no	4.658	4.657	EPSD	TCGA;ICGC;COSMIC	1.932	Down-regulation
CMGC_CDK_CDK9_CDK9_ST	O00267	SUPT5H	P50750	CDK9	S917	Q922H	922	Missense	distal	5	no	4.585	4.372	EPSD	TCGA;ICGC	1.932	Down-regulation
CMGC_CDK_CDK9_CDK9_ST	O00267	SUPT5H	P50750	CDK9	S917	Y911H	911	Missense	distal	-6	no	4.585	4.610	EPSD	TCGA;ICGC;COSMIC	1.932	Up-regulation
CMGC_CDK_CDK9_CDK9_ST	O00267	SUPT5H	P50750	CDK9	S917	G920D	920	Missense	distal	3	no	4.585	4.558	EPSD	TCGA;ICGC;COSMIC	1.932	Down-regulation
CMGC_CDK_CDK9_CDK9_ST	O00267	SUPT5H	P50750	CDK9	S917	A915V	915	Missense	proximal	-2	no	4.585	4.635	EPSD	TCGA;ICGC	1.932	Up-regulation
CMGC_CDK_CDK9_CDK9_ST	O00267	SUPT5H	P50750	CDK9	T967	G969C	969	Missense	proximal	2	no	5.577	5.607	EPSD	TCGA;ICGC;COSMIC	1.932	Up-regulation
CMGC_CDK_CDK9_CDK9_ST	O00267	SUPT5H	P50750	CDK9	T967	S970L	970	Missense	distal	3	no	5.577	5.267	EPSD	TCGA;ICGC;COSMIC	1.932	Down-regulation
CMGC_CDK_CDK9_CDK9_ST	O00267	SUPT5H	P50750	CDK9	S976	G969C	969	Missense	distal	-7	no	2.177	2.189	EPSD	TCGA;ICGC;COSMIC	1.932	Up-regulation
CMGC_CDK_CDK9_CDK9_ST	O00267	SUPT5H	P50750	CDK9	S976	S970L	970	Missense	distal	-6	no	2.177	1.720	EPSD	TCGA;ICGC;COSMIC	1.932	Loss
CMGC_CDK_CDK9_CDK9_ST	O00267	SUPT5H	P50750	CDK9	S1026	E1028D	1028	Missense	proximal	2	no	2.387	2.438	EPSD	TCGA;ICGC;COSMIC	1.932	Up-regulation
CMGC_CDK_CDK9_CDK9_ST	O00267	SUPT5H	P50750	CDK9	S1026	S1024G	1024	Missense	proximal	-2	no	2.387	1.956	EPSD	TCGA;ICGC;COSMIC	1.932	Down-regulation
CMGC_CDK_CDK9_CDK9_ST	O00267	SUPT5H	P50750	CDK9	S1026	V1023G	1023	Missense	distal	-3	no	2.387	2.389	EPSD	TCGA;ICGC;COSMIC	1.932	Up-regulation
CMGC_CDK_CDK9_CDK9_ST	O00267	SUPT5H	P50750	CDK9	T1034	E1028D	1028	Missense	distal	-6	no	5.754	5.655	EPSD	TCGA;ICGC;COSMIC	1.932	Down-regulation
CMGC_CDK_CDK9_CDK9_ST	Q15797	SMAD1	P50750	CDK9	T10	A13T	13	Missense	distal	3	no	2.283	2.371	EPSD	TCGA;ICGC;COSMIC	1.932	Up-regulation
CMGC_CDK_CDK9_CDK9_ST	Q15797	SMAD1	P50750	CDK9	S11	A13T	13	Missense	proximal	2	no	4.480	4.405	EPSD	TCGA;ICGC;COSMIC	1.932	Down-regulation
CMGC_CDK_CDK9_CDK9_ST	Q15797	SMAD1	P50750	CDK9	S62	P61L	61	Missense	proximal	-1	no	2.622	2.585	EPSD	TCGA;ICGC;COSMIC	1.932	Down-regulation
CMGC_CDK_CDK9_CDK9_ST	Q15797	SMAD1	P50750	CDK9	S132	R129K	129	Missense	distal	-3	no	5.932	5.923	EPSD	TCGA;ICGC;COSMIC	1.932	Down-regulation
CMGC_CDK_CDK9_CDK9_ST	Q15797	SMAD1	P50750	CDK9	S132	L139V	139	Missense	distal	7	no	5.932	5.915	EPSD	TCGA;ICGC;COSMIC	1.932	Down-regulation
CMGC_CDK_CDK9_CDK9_ST	Q15797	SMAD1	P50750	CDK9	S187	S190T	190	Missense	distal	3	no	5.904	5.724	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	1.932	Down-regulation
CMGC_CDK_CDK9_CDK9_ST	Q15797	SMAD1	P50750	CDK9	S195	G197V	197	Missense	proximal	2	no	7.020	7.010	PhosphoSitePlus;EPSD	TCGA;ICGC;COSMIC	1.932	Down-regulation
CMGC_CDK_CDK9_CDK9_ST	Q15797	SMAD1	P50750	CDK9	S195	S190T	190	Missense	distal	-5	no	7.020	6.735	PhosphoSitePlus;EPSD	TCGA;ICGC;COSMIC	1.932	Down-regulation
CMGC_CDK_CDK9_CDK9_ST	Q15797	SMAD1	P50750	CDK9	S214	D221G	221	Missense	distal	7	no	5.787	5.757	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	1.932	Down-regulation
CMGC_CDK_CDK9_CDK9_ST	Q15797	SMAD1	P50750	CDK9	S315	R319Q	319	Missense	distal	4	no	2.576	2.628	EPSD	TCGA;ICGC;COSMIC	1.932	Up-regulation
CMGC_CDK_CDK9_CDK9_ST	Q15797	SMAD1	P50750	CDK9	S315	N318D	318	Missense	distal	3	no	2.576	2.425	EPSD	TCGA;ICGC;COSMIC	1.932	Down-regulation
CMGC_CDK_CDK9_CDK9_ST	Q15797	SMAD1	P50750	CDK9	S462	V464L	464	Missense	proximal	2	no	2.834	2.868	EPSD	TCGA;ICGC;COSMIC	1.932	Up-regulation
CMGC_CDK_CDK9_CDK9_ST	P50750	CDK9	P50750	CDK9	S90	R86Q	86	Missense	distal	-4	no	3.904	3.962	EPSD	TCGA;ICGC;COSMIC	1.932	Up-regulation
CMGC_CDK_CDK9_CDK9_ST	P50750	CDK9	P50750	CDK9	S90	N93T	93	Missense	distal	3	no	3.904	3.852	EPSD	TCGA;ICGC;COSMIC	1.932	Down-regulation
CMGC_CDK_CDK9_CDK9_ST	P50750	CDK9	P50750	CDK9	S347	Q352H	352	Missense	distal	5	no	3.411	3.198	EPSD;PhosphoSitePlus	TCGA;ICGC	1.932	Down-regulation
CMGC_CDK_CDK9_CDK9_ST	P50750	CDK9	P50750	CDK9	T350	Q352H	352	Missense	proximal	2	no	3.328	3.387	EPSD	TCGA;ICGC	1.932	Up-regulation
CMGC_CDK_CDK9_CDK9_ST	P50750	CDK9	P50750	CDK9	S353	R358H	358	Missense	distal	5	no	2.921	2.883	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	1.932	Down-regulation
CMGC_CDK_CDK9_CDK9_ST	P50750	CDK9	P50750	CDK9	S353	Q352H	352	Missense	proximal	-1	no	2.921	2.898	EPSD;PhosphoSitePlus	TCGA;ICGC	1.932	Down-regulation
CMGC_CDK_CDK9_CDK9_ST	P50750	CDK9	P50750	CDK9	T354	R358H	358	Missense	distal	4	no	3.986	3.977	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	1.932	Down-regulation
CMGC_CDK_CDK9_CDK9_ST	P50750	CDK9	P50750	CDK9	T354	Q352H	352	Missense	proximal	-2	no	3.986	3.708	EPSD;PhosphoSitePlus	TCGA;ICGC	1.932	Down-regulation
CMGC_CDK_CDK9_CDK9_ST	P50750	CDK9	P50750	CDK9	S357	R358H	358	Missense	proximal	1	no	2.355	1.956	EPSD	TCGA;ICGC;COSMIC	1.932	Down-regulation
CMGC_CDK_CDK9_CDK9_ST	P50750	CDK9	P50750	CDK9	S357	Q352H	352	Missense	distal	-5	no	2.355	2.164	EPSD	TCGA;ICGC	1.932	Down-regulation
CMGC_CDK_CDK9_CDK9_ST	P50750	CDK9	P50750	CDK9	T362	E369Q	369	Missense	distal	7	no	2.325	2.228	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	1.932	Down-regulation
CMGC_CDK_CDK9_CDK9_ST	P50750	CDK9	P50750	CDK9	T362	R358H	358	Missense	distal	-4	no	2.325	2.310	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	1.932	Down-regulation
CMGC_CDK_CDK9_CDK9_ST	P50750	CDK9	P50750	CDK9	T363	E369Q	369	Missense	distal	6	no	2.770	3.014	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	1.932	Up-regulation
CMGC_CDK_CDK9_CDK9_ST	P50750	CDK9	P50750	CDK9	T363	R358H	358	Missense	distal	-5	no	2.770	2.740	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	1.932	Down-regulation
CMGC_CDK_CDK9_CDK9_ST	P50750	CDK9	P50750	CDK9	T363	R370H	370	Missense	distal	7	no	2.770	2.793	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	1.932	Up-regulation
CMGC_CDK_CDK9_CDK9_ST	P84022	SMAD3	P50750	CDK9	T8	P9S	9	Missense	proximal	1	no	5.649	1.915	EPSD	TCGA;ICGC;COSMIC	1.932	Loss
CMGC_CDK_CDK9_CDK9_ST	P84022	SMAD3	P50750	CDK9	T132	L135V	135	Missense	distal	3	no	5.100	5.158	EPSD	TCGA;ICGC;COSMIC	1.932	Up-regulation
CMGC_CDK_CDK9_CDK9_ST	P84022	SMAD3	P50750	CDK9	T132	Q128H	128	Missense	distal	-4	no	5.100	5.026	EPSD	TCGA;ICGC;COSMIC	1.932	Down-regulation
CMGC_CDK_CDK9_CDK9_ST	P84022	SMAD3	P50750	CDK9	T179	E178D	178	Missense	proximal	-1	no	5.191	5.173	EPSD;PhosphoSitePlus	TCGA;COSMIC	1.932	Down-regulation
CMGC_CDK_CDK9_CDK9_ST	P84022	SMAD3	P50750	CDK9	S204	S204Y	204	Missense	central	0	yes	5.359	0.000	EPSD	TCGA;ICGC;COSMIC	1.932	Loss
CMGC_CDK_CDK9_CDK9_ST	P84022	SMAD3	P50750	CDK9	S204	S199N	199	Missense	distal	-5	no	5.359	5.129	EPSD	TCGA	1.932	Down-regulation
CMGC_CDK_CDK9_CDK9_ST	P84022	SMAD3	P50750	CDK9	S208	S204Y	204	Missense	distal	-4	no	6.205	6.064	PhosphoSitePlus;EPSD	TCGA;ICGC;COSMIC	1.932	Down-regulation
CMGC_CDK_CDK9_CDK9_ST	P84022	SMAD3	P50750	CDK9	T412	S416F	416	Missense	distal	4	no	2.233	2.081	EPSD	TCGA;ICGC;COSMIC	1.932	Down-regulation
CMGC_CDK_CDK9_CDK9_ST	P84022	SMAD3	P50750	CDK9	T412	S418I	418	Missense	distal	6	no	2.233	1.639	EPSD	TCGA;COSMIC	1.932	Loss
CMGC_CDK_CDK9_CDK9_ST	P84022	SMAD3	P50750	CDK9	T412	P417L	417	Missense	distal	5	no	2.233	1.908	EPSD	TCGA;ICGC;COSMIC	1.932	Loss
CMGC_CDK_CDK9_CDK9_ST	P84022	SMAD3	P50750	CDK9	T412	S418N	418	Missense	distal	6	no	2.233	1.984	EPSD	TCGA;ICGC;COSMIC	1.932	Down-regulation
CMGC_CDK_CDK9_CDK9_ST	P84022	SMAD3	P50750	CDK9	T412	Q405L	405	Missense	distal	-7	no	2.233	2.271	EPSD	TCGA;ICGC;COSMIC	1.932	Up-regulation
CMGC_CDK_CDK9_CDK9_ST	P84022	SMAD3	P50750	CDK9	S416	S416F	416	Missense	central	0	yes	5.181	0.000	EPSD	TCGA;ICGC;COSMIC	1.932	Loss
CMGC_CDK_CDK9_CDK9_ST	P84022	SMAD3	P50750	CDK9	S416	S418I	418	Missense	proximal	2	no	5.181	5.364	EPSD	TCGA;COSMIC	1.932	Up-regulation
CMGC_CDK_CDK9_CDK9_ST	P84022	SMAD3	P50750	CDK9	S416	R420H	420	Missense	distal	4	no	5.181	5.172	EPSD	TCGA;ICGC;COSMIC	1.932	Down-regulation
CMGC_CDK_CDK9_CDK9_ST	P84022	SMAD3	P50750	CDK9	S416	S423R	423	Missense	distal	7	no	5.181	5.410	EPSD	TCGA;ICGC;COSMIC	1.932	Up-regulation
CMGC_CDK_CDK9_CDK9_ST	P84022	SMAD3	P50750	CDK9	S416	P417L	417	Missense	proximal	1	no	5.181	-0.417	EPSD	TCGA;ICGC;COSMIC	1.932	Loss
CMGC_CDK_CDK9_CDK9_ST	P84022	SMAD3	P50750	CDK9	S416	S418N	418	Missense	proximal	2	no	5.181	5.286	EPSD	TCGA;ICGC;COSMIC	1.932	Up-regulation
CMGC_CDK_CDK9_CDK9_ST	P84022	SMAD3	P50750	CDK9	S422	S416F	416	Missense	distal	-6	no	2.348	1.910	EPSD	TCGA;ICGC;COSMIC	1.932	Loss
CMGC_CDK_CDK9_CDK9_ST	P84022	SMAD3	P50750	CDK9	S422	S418I	418	Missense	distal	-4	no	2.348	2.205	EPSD	TCGA;COSMIC	1.932	Down-regulation
CMGC_CDK_CDK9_CDK9_ST	P84022	SMAD3	P50750	CDK9	S422	R420H	420	Missense	proximal	-2	no	2.348	2.276	EPSD	TCGA;ICGC;COSMIC	1.932	Down-regulation
CMGC_CDK_CDK9_CDK9_ST	P84022	SMAD3	P50750	CDK9	S422	S423R	423	Missense	proximal	1	no	2.348	1.906	EPSD	TCGA;ICGC;COSMIC	1.932	Loss
CMGC_CDK_CDK9_CDK9_ST	P84022	SMAD3	P50750	CDK9	S422	P417L	417	Missense	distal	-5	no	2.348	1.968	EPSD	TCGA;ICGC;COSMIC	1.932	Down-regulation
CMGC_CDK_CDK9_CDK9_ST	P84022	SMAD3	P50750	CDK9	S422	S418N	418	Missense	distal	-4	no	2.348	2.273	EPSD	TCGA;ICGC;COSMIC	1.932	Down-regulation
CMGC_CDK_CDK9_CDK9_ST	P24928	POLR2A	P50750	CDK9	S27	F23L	23	Missense	distal	-4	no	4.480	4.490	EPSD	TCGA;ICGC;COSMIC	1.932	Up-regulation
CMGC_CDK_CDK9_CDK9_ST	P24928	POLR2A	P50750	CDK9	T46	R51P	51	Missense	distal	5	no	1.956	2.171	EPSD	TCGA;ICGC;COSMIC	1.932	Up-regulation
CMGC_CDK_CDK9_CDK9_ST	P24928	POLR2A	P50750	CDK9	T46	P52L	52	Missense	distal	6	no	1.956	1.351	EPSD	TCGA;ICGC;COSMIC	1.932	Loss
CMGC_CDK_CDK9_CDK9_ST	P24928	POLR2A	P50750	CDK9	S217	L215R	215	Missense	proximal	-2	no	5.452	5.684	EPSD	TCGA;ICGC;COSMIC	1.932	Up-regulation
CMGC_CDK_CDK9_CDK9_ST	P24928	POLR2A	P50750	CDK9	S217	E223K	223	Missense	distal	6	no	5.452	5.508	EPSD	TCGA;ICGC;COSMIC	1.932	Up-regulation
CMGC_CDK_CDK9_CDK9_ST	P24928	POLR2A	P50750	CDK9	S217	L215P	215	Missense	proximal	-2	no	5.452	6.240	EPSD	TCGA;ICGC	1.932	Up-regulation
CMGC_CDK_CDK9_CDK9_ST	P24928	POLR2A	P50750	CDK9	S217	R220Q	220	Missense	distal	3	no	5.452	5.576	EPSD	TCGA;ICGC	1.932	Up-regulation
CMGC_CDK_CDK9_CDK9_ST	P24928	POLR2A	P50750	CDK9	T368	P369T	369	Missense	proximal	1	no	6.146	2.127	EPSD	TCGA;ICGC;COSMIC	1.932	Down-regulation
CMGC_CDK_CDK9_CDK9_ST	P24928	POLR2A	P50750	CDK9	S777	G773R	773	Missense	distal	-4	no	2.471	2.474	EPSD	TCGA;ICGC	1.932	Up-regulation
CMGC_CDK_CDK9_CDK9_ST	P24928	POLR2A	P50750	CDK9	S1508	M1510L	1510	Missense	proximal	2	no	3.395	3.437	EPSD	TCGA;ICGC	1.932	Up-regulation
CMGC_CDK_CDK9_CDK9_ST	P24928	POLR2A	P50750	CDK9	S1508	G1504V	1504	Missense	distal	-4	no	3.395	3.368	EPSD	TCGA;ICGC	1.932	Down-regulation
CMGC_CDK_CDK9_CDK9_ST	P24928	POLR2A	P50750	CDK9	S1508	F1502L	1502	Missense	distal	-6	no	3.395	3.376	EPSD	TCGA;ICGC	1.932	Down-regulation
CMGC_CDK_CDK9_CDK9_ST	P24928	POLR2A	P50750	CDK9	S1514	M1510L	1510	Missense	distal	-4	no	4.572	4.537	EPSD	TCGA;ICGC	1.932	Down-regulation
CMGC_CDK_CDK9_CDK9_ST	P24928	POLR2A	P50750	CDK9	S1514	A1516V	1516	Missense	proximal	2	no	4.572	4.548	EPSD	TCGA;ICGC	1.932	Down-regulation
CMGC_CDK_CDK9_CDK9_ST	P24928	POLR2A	P50750	CDK9	S1514	M1517V	1517	Missense	distal	3	no	4.572	4.549	EPSD	TCGA;ICGC	1.932	Down-regulation
CMGC_CDK_CDK9_CDK9_ST	P24928	POLR2A	P50750	CDK9	T1518	A1516V	1516	Missense	proximal	-2	no	4.591	4.641	EPSD	TCGA;ICGC	1.932	Up-regulation
CMGC_CDK_CDK9_CDK9_ST	P24928	POLR2A	P50750	CDK9	T1518	M1517V	1517	Missense	proximal	-1	no	4.591	4.579	EPSD	TCGA;ICGC	1.932	Down-regulation
CMGC_CDK_CDK9_CDK9_ST	P24928	POLR2A	P50750	CDK9	T1525	A1527V	1527	Missense	proximal	2	no	5.379	5.355	PhosphoSitePlus	TCGA;ICGC	1.932	Down-regulation
CMGC_CDK_CDK9_CDK9_ST	P24928	POLR2A	P50750	CDK9	S1532	A1527V	1527	Missense	distal	-5	no	5.269	5.262	EPSD	TCGA;ICGC	1.932	Down-regulation
CMGC_CDK_CDK9_CDK9_ST	P24928	POLR2A	P50750	CDK9	T1568	P1572L	1572	Missense	distal	4	no	5.440	5.398	EPSD	TCGA;ICGC	1.932	Down-regulation
CMGC_CDK_CDK9_CDK9_ST	P24928	POLR2A	P50750	CDK9	T1568	G1570S	1570	Missense	proximal	2	no	5.440	5.261	EPSD	TCGA;ICGC	1.932	Down-regulation
CMGC_CDK_CDK9_CDK9_ST	P24928	POLR2A	P50750	CDK9	S1571	P1572L	1572	Missense	proximal	1	no	5.570	-0.028	EPSD	TCGA;ICGC	1.932	Loss
CMGC_CDK_CDK9_CDK9_ST	P24928	POLR2A	P50750	CDK9	S1571	G1570S	1570	Missense	proximal	-1	no	5.570	5.633	EPSD	TCGA;ICGC	1.932	Up-regulation
CMGC_CDK_CDK9_CDK9_ST	P24928	POLR2A	P50750	CDK9	S1574	P1572L	1572	Missense	proximal	-2	no	6.846	6.057	EPSD	TCGA;ICGC	1.932	Down-regulation
CMGC_CDK_CDK9_CDK9_ST	P24928	POLR2A	P50750	CDK9	S1574	G1570S	1570	Missense	distal	-4	no	6.846	6.965	EPSD	TCGA;ICGC	1.932	Up-regulation
CMGC_CDK_CDK9_CDK9_ST	P24928	POLR2A	P50750	CDK9	S1590	P1591L	1591	Missense	proximal	1	no	3.545	-2.054	EPSD	TCGA;ICGC	1.932	Loss
CMGC_CDK_CDK9_CDK9_ST	P24928	POLR2A	P50750	CDK9	S1594	P1591L	1591	Missense	distal	-3	no	3.394	3.479	EPSD	TCGA;ICGC	1.932	Up-regulation
CMGC_CDK_CDK9_CDK9_ST	P24928	POLR2A	P50750	CDK9	S1597	R1603H	1603	Missense	distal	6	no	4.299	4.250	EPSD	TCGA;ICGC	1.932	Down-regulation
CMGC_CDK_CDK9_CDK9_ST	P24928	POLR2A	P50750	CDK9	S1597	P1591L	1591	Missense	distal	-6	no	4.299	3.710	EPSD	TCGA;ICGC	1.932	Down-regulation
CMGC_CDK_CDK9_CDK9_ST	P24928	POLR2A	P50750	CDK9	T1618	T1625A	1625	Missense	distal	7	no	2.563	2.667	EPSD;PhosphoSitePlus	TCGA;ICGC	1.932	Up-regulation
CMGC_CDK_CDK9_CDK9_ST	P24928	POLR2A	P50750	CDK9	S1619	T1625A	1625	Missense	distal	6	no	4.556	4.371	EPSD;PhosphoSitePlus	TCGA;ICGC	1.932	Down-regulation
CMGC_CDK_CDK9_CDK9_ST	P24928	POLR2A	P50750	CDK9	S1626	T1625A	1625	Missense	proximal	-1	no	4.234	4.211	EPSD	TCGA;ICGC	1.932	Down-regulation
CMGC_CDK_CDK9_CDK9_ST	P24928	POLR2A	P50750	CDK9	S1626	S1630Y	1630	Missense	distal	4	no	4.234	4.098	EPSD	TCGA	1.932	Down-regulation
CMGC_CDK_CDK9_CDK9_ST	P24928	POLR2A	P50750	CDK9	S1626	P1631S	1631	Missense	distal	5	no	4.234	4.354	EPSD	TCGA;ICGC	1.932	Up-regulation
CMGC_CDK_CDK9_CDK9_ST	P24928	POLR2A	P50750	CDK9	S1626	P1631L	1631	Missense	distal	5	no	4.234	3.909	EPSD	TCGA;ICGC	1.932	Down-regulation
CMGC_CDK_CDK9_CDK9_ST	P24928	POLR2A	P50750	CDK9	S1675	S1677N	1677	Missense	proximal	2	no	4.267	4.372	EPSD	TCGA;ICGC	1.932	Up-regulation
CMGC_CDK_CDK9_CDK9_ST	P24928	POLR2A	P50750	CDK9	S1682	S1677N	1677	Missense	distal	-5	no	4.267	4.037	EPSD	TCGA;ICGC	1.932	Down-regulation
CMGC_CDK_CDK9_CDK9_ST	P24928	POLR2A	P50750	CDK9	S1689	T1695M	1695	Missense	distal	6	no	4.267	4.121	EPSD	TCGA;ICGC	1.932	Down-regulation
CMGC_CDK_CDK9_CDK9_ST	P24928	POLR2A	P50750	CDK9	S1696	T1702I	1702	Missense	distal	6	no	4.267	4.036	EPSD	TCGA;ICGC	1.932	Down-regulation
CMGC_CDK_CDK9_CDK9_ST	P24928	POLR2A	P50750	CDK9	S1696	T1702S	1702	Missense	distal	6	no	4.267	4.630	EPSD	TCGA;ICGC	1.932	Up-regulation
CMGC_CDK_CDK9_CDK9_ST	P24928	POLR2A	P50750	CDK9	S1696	T1695M	1695	Missense	proximal	-1	no	4.267	4.257	EPSD	TCGA;ICGC	1.932	Down-regulation
CMGC_CDK_CDK9_CDK9_ST	P24928	POLR2A	P50750	CDK9	S1696	S1700L	1700	Missense	distal	4	no	4.267	4.132	EPSD	TCGA;ICGC	1.932	Down-regulation
CMGC_CDK_CDK9_CDK9_ST	P24928	POLR2A	P50750	CDK9	S1703	T1702I	1702	Missense	proximal	-1	no	4.267	4.246	EPSD	TCGA;ICGC	1.932	Down-regulation
CMGC_CDK_CDK9_CDK9_ST	P24928	POLR2A	P50750	CDK9	S1703	T1702S	1702	Missense	proximal	-1	no	4.267	4.315	EPSD	TCGA;ICGC	1.932	Up-regulation
CMGC_CDK_CDK9_CDK9_ST	P24928	POLR2A	P50750	CDK9	S1703	S1700L	1700	Missense	distal	-3	no	4.267	4.356	EPSD	TCGA;ICGC	1.932	Up-regulation
CMGC_CDK_CDK9_CDK9_ST	P24928	POLR2A	P50750	CDK9	S1731	P1732L	1732	Missense	proximal	1	no	4.514	-1.084	EPSD	TCGA;ICGC;CCLE	1.932	Loss
CMGC_CDK_CDK9_CDK9_ST	P24928	POLR2A	P50750	CDK9	S1731	S1735A	1735	Missense	distal	4	no	4.514	4.388	EPSD	TCGA;ICGC	1.932	Down-regulation
CMGC_CDK_CDK9_CDK9_ST	P24928	POLR2A	P50750	CDK9	S1738	T1744I	1744	Missense	distal	6	no	4.313	4.082	EPSD	TCGA;ICGC	1.932	Down-regulation
CMGC_CDK_CDK9_CDK9_ST	P24928	POLR2A	P50750	CDK9	S1738	S1745N	1745	Missense	distal	7	no	4.313	4.454	EPSD	TCGA;ICGC	1.932	Up-regulation
CMGC_CDK_CDK9_CDK9_ST	P24928	POLR2A	P50750	CDK9	S1738	P1732L	1732	Missense	distal	-6	no	4.313	3.724	EPSD	TCGA;ICGC;CCLE	1.932	Down-regulation
CMGC_CDK_CDK9_CDK9_ST	P24928	POLR2A	P50750	CDK9	S1738	S1735A	1735	Missense	distal	-3	no	4.313	4.402	EPSD	TCGA;ICGC	1.932	Up-regulation
CMGC_CDK_CDK9_CDK9_ST	P24928	POLR2A	P50750	CDK9	S1766	P1764S	1764	Missense	proximal	-2	no	4.505	4.266	EPSD	TCGA;ICGC	1.932	Down-regulation
CMGC_CDK_CDK9_CDK9_ST	P24928	POLR2A	P50750	CDK9	S1766	T1772I	1772	Missense	distal	6	no	4.505	4.274	EPSD	TCGA;ICGC	1.932	Down-regulation
CMGC_CDK_CDK9_CDK9_ST	P24928	POLR2A	P50750	CDK9	S1794	S1787F	1787	Missense	distal	-7	no	4.472	4.535	EPSD	TCGA;ICGC	1.932	Up-regulation
CMGC_CDK_CDK9_CDK9_ST	P24928	POLR2A	P50750	CDK9	T1812	P1816A	1816	Missense	distal	4	no	5.086	5.054	EPSD	TCGA;ICGC	1.932	Down-regulation
CMGC_CDK_CDK9_CDK9_ST	P24928	POLR2A	P50750	CDK9	T1812	Y1818C	1818	Missense	distal	6	no	5.086	4.966	EPSD	TCGA	1.932	Down-regulation
CMGC_CDK_CDK9_CDK9_ST	P24928	POLR2A	P50750	CDK9	T1812	P1809S	1809	Missense	distal	-3	no	5.086	5.082	EPSD	TCGA;ICGC	1.932	Down-regulation
CMGC_CDK_CDK9_CDK9_ST	P24928	POLR2A	P50750	CDK9	S1815	P1816A	1816	Missense	proximal	1	no	5.089	-0.076	EPSD	TCGA;ICGC	1.932	Loss
CMGC_CDK_CDK9_CDK9_ST	P24928	POLR2A	P50750	CDK9	S1815	Y1818C	1818	Missense	distal	3	no	5.089	5.023	EPSD	TCGA	1.932	Down-regulation
CMGC_CDK_CDK9_CDK9_ST	P24928	POLR2A	P50750	CDK9	S1815	P1809S	1809	Missense	distal	-6	no	5.089	4.957	EPSD	TCGA;ICGC	1.932	Down-regulation
CMGC_CDK_CDK9_CDK9_ST	P24928	POLR2A	P50750	CDK9	T1819	P1816A	1816	Missense	distal	-3	no	4.618	4.701	EPSD	TCGA;ICGC	1.932	Up-regulation
CMGC_CDK_CDK9_CDK9_ST	P24928	POLR2A	P50750	CDK9	T1819	Y1818C	1818	Missense	proximal	-1	no	4.618	4.613	EPSD	TCGA	1.932	Down-regulation
CMGC_CDK_CDK9_CDK9_ST	P24928	POLR2A	P50750	CDK9	S1822	P1816A	1816	Missense	distal	-6	no	4.430	3.903	EPSD	TCGA;ICGC	1.932	Down-regulation
CMGC_CDK_CDK9_CDK9_ST	P24928	POLR2A	P50750	CDK9	S1822	Y1818C	1818	Missense	distal	-4	no	4.430	4.405	EPSD	TCGA	1.932	Down-regulation
CMGC_CDK_CDK9_CDK9_ST	P24928	POLR2A	P50750	CDK9	T1840	S1845P	1845	Missense	distal	5	no	4.259	4.139	EPSD	TCGA;GDSC;CCLE	1.932	Down-regulation
CMGC_CDK_CDK9_CDK9_ST	P24928	POLR2A	P50750	CDK9	T1840	S1845Y	1845	Missense	distal	5	no	4.259	3.865	EPSD	TCGA;ICGC	1.932	Down-regulation
CMGC_CDK_CDK9_CDK9_ST	P24928	POLR2A	P50750	CDK9	S1843	S1845P	1845	Missense	proximal	2	no	4.591	4.629	EPSD	TCGA;GDSC;CCLE	1.932	Up-regulation
CMGC_CDK_CDK9_CDK9_ST	P24928	POLR2A	P50750	CDK9	S1843	S1845Y	1845	Missense	proximal	2	no	4.591	4.784	EPSD	TCGA;ICGC	1.932	Up-regulation
CMGC_CDK_CDK9_CDK9_ST	P24928	POLR2A	P50750	CDK9	S1847	S1845P	1845	Missense	proximal	-2	no	4.003	4.242	EPSD	TCGA;GDSC;CCLE	1.932	Up-regulation
CMGC_CDK_CDK9_CDK9_ST	P24928	POLR2A	P50750	CDK9	S1847	S1845Y	1845	Missense	proximal	-2	no	4.003	3.592	EPSD	TCGA;ICGC	1.932	Down-regulation
CMGC_CDK_CDK9_CDK9_ST	P24928	POLR2A	P50750	CDK9	S1849	S1845P	1845	Missense	distal	-4	no	2.265	2.245	EPSD	TCGA;GDSC;CCLE	1.932	Down-regulation
CMGC_CDK_CDK9_CDK9_ST	P24928	POLR2A	P50750	CDK9	S1849	S1845Y	1845	Missense	distal	-4	no	2.265	2.123	EPSD	TCGA;ICGC	1.932	Down-regulation
CMGC_CDK_CDK9_CDK9_ST	P24928	POLR2A	P50750	CDK9	S1850	S1845P	1845	Missense	distal	-5	no	4.655	4.569	EPSD	TCGA;GDSC;CCLE	1.932	Down-regulation
CMGC_CDK_CDK9_CDK9_ST	P24928	POLR2A	P50750	CDK9	S1850	S1857C	1857	Missense	distal	7	no	4.655	4.988	EPSD	TCGA;ICGC	1.932	Up-regulation
CMGC_CDK_CDK9_CDK9_ST	P24928	POLR2A	P50750	CDK9	S1850	S1845Y	1845	Missense	distal	-5	no	4.655	4.254	EPSD	TCGA;ICGC	1.932	Down-regulation
CMGC_CDK_CDK9_CDK9_ST	P24928	POLR2A	P50750	CDK9	S1850	S1857F	1857	Missense	distal	7	no	4.655	4.983	EPSD	TCGA	1.932	Up-regulation
CMGC_CDK_CDK9_CDK9_ST	P24928	POLR2A	P50750	CDK9	T1854	S1857C	1857	Missense	distal	3	no	4.083	3.779	EPSD	TCGA;ICGC	1.932	Down-regulation
CMGC_CDK_CDK9_CDK9_ST	P24928	POLR2A	P50750	CDK9	T1854	S1857F	1857	Missense	distal	3	no	4.083	3.780	EPSD	TCGA	1.932	Down-regulation
CMGC_CDK_CDK9_CDK9_ST	P24928	POLR2A	P50750	CDK9	T1856	S1857C	1857	Missense	proximal	1	no	2.320	1.011	EPSD	TCGA;ICGC	1.932	Loss
CMGC_CDK_CDK9_CDK9_ST	P24928	POLR2A	P50750	CDK9	T1856	S1857F	1857	Missense	proximal	1	no	2.320	1.017	EPSD	TCGA	1.932	Loss
CMGC_CDK_CDK9_CDK9_ST	P24928	POLR2A	P50750	CDK9	S1857	S1857C	1857	Missense	central	0	yes	4.315	0.000	EPSD	TCGA;ICGC	1.932	Loss
CMGC_CDK_CDK9_CDK9_ST	P24928	POLR2A	P50750	CDK9	S1857	S1857F	1857	Missense	central	0	yes	4.315	0.000	EPSD	TCGA	1.932	Loss
CMGC_CDK_CDK9_CDK9_ST	P24928	POLR2A	P50750	CDK9	S1861	S1857C	1857	Missense	distal	-4	no	3.999	3.833	EPSD	TCGA;ICGC	1.932	Down-regulation
CMGC_CDK_CDK9_CDK9_ST	P24928	POLR2A	P50750	CDK9	S1861	S1857F	1857	Missense	distal	-4	no	3.999	3.835	EPSD	TCGA	1.932	Down-regulation
CMGC_CDK_CDK9_CDK9_ST	P24928	POLR2A	P50750	CDK9	T1863	S1857C	1857	Missense	distal	-6	no	2.535	2.092	EPSD	TCGA;ICGC	1.932	Down-regulation
CMGC_CDK_CDK9_CDK9_ST	P24928	POLR2A	P50750	CDK9	T1863	S1857F	1857	Missense	distal	-6	no	2.535	2.097	EPSD	TCGA	1.932	Down-regulation
CMGC_CDK_CDK9_CDK9_ST	P24928	POLR2A	P50750	CDK9	S1864	S1857C	1857	Missense	distal	-7	no	4.218	4.282	EPSD	TCGA;ICGC	1.932	Up-regulation
CMGC_CDK_CDK9_CDK9_ST	P24928	POLR2A	P50750	CDK9	S1864	S1857F	1857	Missense	distal	-7	no	4.218	4.281	EPSD	TCGA	1.932	Up-regulation
CMGC_CDK_CDK9_CDK9_ST	P24928	POLR2A	P50750	CDK9	S1868	Y1874H	1874	Missense	distal	6	no	3.736	3.778	EPSD	TCGA;ICGC	1.932	Up-regulation
CMGC_CDK_CDK9_CDK9_ST	P24928	POLR2A	P50750	CDK9	S1868	S1875L	1875	Missense	distal	7	no	3.736	4.037	EPSD	TCGA;ICGC	1.932	Up-regulation
CMGC_CDK_CDK9_CDK9_ST	P24928	POLR2A	P50750	CDK9	T1870	Y1874H	1874	Missense	distal	4	no	2.346	2.358	EPSD	TCGA;ICGC	1.932	Up-regulation
CMGC_CDK_CDK9_CDK9_ST	P24928	POLR2A	P50750	CDK9	T1870	S1875L	1875	Missense	distal	5	no	2.346	1.901	EPSD	TCGA;ICGC	1.932	Loss
CMGC_CDK_CDK9_CDK9_ST	P24928	POLR2A	P50750	CDK9	S1871	Y1874H	1874	Missense	distal	3	no	4.206	4.232	EPSD	TCGA;ICGC	1.932	Up-regulation
CMGC_CDK_CDK9_CDK9_ST	P24928	POLR2A	P50750	CDK9	S1871	S1875L	1875	Missense	distal	4	no	4.206	4.071	EPSD	TCGA;ICGC	1.932	Down-regulation
CMGC_CDK_CDK9_CDK9_ST	P24928	POLR2A	P50750	CDK9	S1875	Y1874H	1874	Missense	proximal	-1	no	3.827	3.842	EPSD	TCGA;ICGC	1.932	Up-regulation
CMGC_CDK_CDK9_CDK9_ST	P24928	POLR2A	P50750	CDK9	S1875	S1875L	1875	Missense	central	0	yes	3.827	0.000	EPSD	TCGA;ICGC	1.932	Loss
CMGC_CDK_CDK9_CDK9_ST	P24928	POLR2A	P50750	CDK9	T1877	Y1874H	1874	Missense	distal	-3	no	2.798	2.786	EPSD	TCGA;ICGC	1.932	Down-regulation
CMGC_CDK_CDK9_CDK9_ST	P24928	POLR2A	P50750	CDK9	T1877	S1875L	1875	Missense	proximal	-2	no	2.798	2.247	EPSD	TCGA;ICGC	1.932	Down-regulation
CMGC_CDK_CDK9_CDK9_ST	P24928	POLR2A	P50750	CDK9	S1878	Y1874H	1874	Missense	distal	-4	no	4.747	4.757	EPSD	TCGA;ICGC	1.932	Up-regulation
CMGC_CDK_CDK9_CDK9_ST	P24928	POLR2A	P50750	CDK9	S1878	S1875L	1875	Missense	distal	-3	no	4.747	4.837	EPSD	TCGA;ICGC	1.932	Up-regulation
CMGC_CDK_CDK9_CDK9_ST	P24928	POLR2A	P50750	CDK9	S1882	S1875L	1875	Missense	distal	-7	no	3.794	3.856	EPSD	TCGA;ICGC	1.932	Up-regulation
CMGC_CDK_CDK9_CDK9_ST	P24928	POLR2A	P50750	CDK9	S1882	K1887N	1887	Missense	distal	5	no	3.794	3.875	EPSD	TCGA;ICGC	1.932	Up-regulation
CMGC_CDK_CDK9_CDK9_ST	P24928	POLR2A	P50750	CDK9	T1884	K1887N	1887	Missense	distal	3	no	2.285	2.320	EPSD	TCGA;ICGC	1.932	Up-regulation
CMGC_CDK_CDK9_CDK9_ST	P24928	POLR2A	P50750	CDK9	T1885	K1887N	1887	Missense	proximal	2	no	4.655	4.639	EPSD	TCGA;ICGC	1.932	Down-regulation
CMGC_CDK_CDK9_CDK9_ST	P24928	POLR2A	P50750	CDK9	S1889	S1896F	1896	Missense	distal	7	no	3.452	3.780	EPSD	TCGA;ICGC	1.932	Up-regulation
CMGC_CDK_CDK9_CDK9_ST	P24928	POLR2A	P50750	CDK9	S1889	K1887N	1887	Missense	proximal	-2	no	3.452	3.588	EPSD	TCGA;ICGC	1.932	Up-regulation
CMGC_CDK_CDK9_CDK9_ST	P24928	POLR2A	P50750	CDK9	T1891	T1898A	1898	Missense	distal	7	no	1.833	1.937	EPSD	TCGA;ICGC	1.932	Gain
CMGC_CDK_CDK9_CDK9_ST	P24928	POLR2A	P50750	CDK9	S1892	T1898A	1898	Missense	distal	6	no	4.537	4.352	EPSD	TCGA;ICGC	1.932	Down-regulation
CMGC_CDK_CDK9_CDK9_ST	P24928	POLR2A	P50750	CDK9	S1892	S1896F	1896	Missense	distal	4	no	4.537	4.385	EPSD	TCGA;ICGC	1.932	Down-regulation
CMGC_CDK_CDK9_CDK9_ST	P24928	POLR2A	P50750	CDK9	S1892	K1887N	1887	Missense	distal	-5	no	4.537	4.598	EPSD	TCGA;ICGC	1.932	Up-regulation
CMGC_CDK_CDK9_CDK9_ST	P24928	POLR2A	P50750	CDK9	T1894	S1896F	1896	Missense	proximal	2	no	1.855	2.058	EPSD	TCGA;ICGC	1.932	Gain
CMGC_CDK_CDK9_CDK9_ST	P24928	POLR2A	P50750	CDK9	S1896	T1898A	1898	Missense	proximal	2	no	3.763	3.837	EPSD	TCGA;ICGC	1.932	Up-regulation
CMGC_CDK_CDK9_CDK9_ST	P24928	POLR2A	P50750	CDK9	S1896	S1896F	1896	Missense	central	0	yes	3.763	0.000	EPSD	TCGA;ICGC	1.932	Loss
CMGC_CDK_CDK9_CDK9_ST	P24928	POLR2A	P50750	CDK9	T1898	T1898A	1898	Missense	central	0	yes	2.177	0.000	EPSD	TCGA;ICGC	1.932	Loss
CMGC_CDK_CDK9_CDK9_ST	P24928	POLR2A	P50750	CDK9	T1898	S1896F	1896	Missense	proximal	-2	no	2.177	1.658	EPSD	TCGA;ICGC	1.932	Loss
CMGC_CDK_CDK9_CDK9_ST	P24928	POLR2A	P50750	CDK9	S1899	T1898A	1898	Missense	proximal	-1	no	4.454	4.430	EPSD	TCGA;ICGC	1.932	Down-regulation
CMGC_CDK_CDK9_CDK9_ST	P24928	POLR2A	P50750	CDK9	S1899	S1896F	1896	Missense	distal	-3	no	4.454	4.545	EPSD	TCGA;ICGC	1.932	Up-regulation
CMGC_CDK_CDK9_CDK9_ST	P24928	POLR2A	P50750	CDK9	T1903	T1898A	1898	Missense	distal	-5	no	3.703	3.571	EPSD	TCGA;ICGC	1.932	Down-regulation
CMGC_CDK_CDK9_CDK9_ST	P24928	POLR2A	P50750	CDK9	T1903	P1907S	1907	Missense	distal	4	no	3.703	3.796	EPSD	TCGA;ICGC	1.932	Up-regulation
CMGC_CDK_CDK9_CDK9_ST	P24928	POLR2A	P50750	CDK9	T1903	S1896F	1896	Missense	distal	-7	no	3.703	3.765	EPSD	TCGA;ICGC	1.932	Up-regulation
CMGC_CDK_CDK9_CDK9_ST	P24928	POLR2A	P50750	CDK9	T1905	T1898A	1898	Missense	distal	-7	no	2.161	2.184	EPSD	TCGA;ICGC	1.932	Up-regulation
CMGC_CDK_CDK9_CDK9_ST	P24928	POLR2A	P50750	CDK9	T1905	P1907S	1907	Missense	proximal	2	no	2.161	2.123	EPSD	TCGA;ICGC	1.932	Down-regulation
CMGC_CDK_CDK9_CDK9_ST	P24928	POLR2A	P50750	CDK9	S1906	P1907S	1907	Missense	proximal	1	no	4.351	0.617	EPSD	TCGA;ICGC	1.932	Loss
CMGC_CDK_CDK9_CDK9_ST	P24928	POLR2A	P50750	CDK9	S1910	P1907S	1907	Missense	distal	-3	no	3.898	3.893	EPSD	TCGA;ICGC	1.932	Down-regulation
CMGC_CDK_CDK9_CDK9_ST	P24928	POLR2A	P50750	CDK9	T1912	P1907S	1907	Missense	distal	-5	no	2.660	2.746	EPSD	TCGA;ICGC	1.932	Up-regulation
CMGC_CDK_CDK9_CDK9_ST	P24928	POLR2A	P50750	CDK9	S1913	P1907S	1907	Missense	distal	-6	no	4.458	4.326	EPSD	TCGA;ICGC	1.932	Down-regulation
CMGC_CDK_CDK9_CDK9_ST	P24928	POLR2A	P50750	CDK9	S1924	S1931L	1931	Missense	distal	7	no	3.881	4.182	EPSD	TCGA;ICGC	1.932	Up-regulation
CMGC_CDK_CDK9_CDK9_ST	P24928	POLR2A	P50750	CDK9	T1926	S1931L	1931	Missense	distal	5	no	2.763	2.318	EPSD	TCGA;ICGC	1.932	Down-regulation
CMGC_CDK_CDK9_CDK9_ST	P24928	POLR2A	P50750	CDK9	S1927	S1931L	1931	Missense	distal	4	no	4.481	4.346	EPSD	TCGA;ICGC	1.932	Down-regulation
CMGC_CDK_CDK9_CDK9_ST	P24928	POLR2A	P50750	CDK9	T1929	S1931L	1931	Missense	proximal	2	no	2.071	2.274	EPSD	TCGA;ICGC	1.932	Up-regulation
CMGC_CDK_CDK9_CDK9_ST	P24928	POLR2A	P50750	CDK9	S1931	S1931L	1931	Missense	central	0	yes	4.637	0.000	EPSD	TCGA;ICGC	1.932	Loss
CMGC_CDK_CDK9_CDK9_ST	P24928	POLR2A	P50750	CDK9	S1934	S1931L	1931	Missense	distal	-3	no	4.273	4.363	EPSD	TCGA;ICGC	1.932	Up-regulation
CMGC_CDK_CDK9_CDK9_ST	P24928	POLR2A	P50750	CDK9	S1941	S1944F	1944	Missense	distal	3	no	4.343	4.040	EPSD	TCGA;ICGC	1.932	Down-regulation
CMGC_CDK_CDK9_CDK9_ST	P24928	POLR2A	P50750	CDK9	T1943	S1944F	1944	Missense	proximal	1	no	3.014	1.712	EPSD	TCGA;ICGC	1.932	Loss
CMGC_CDK_CDK9_CDK9_ST	P24928	POLR2A	P50750	CDK9	S1944	S1944F	1944	Missense	central	0	yes	5.921	0.000	EPSD	TCGA;ICGC	1.932	Loss
CMGC_CDK_CDK9_CDK9_ST	P24928	POLR2A	P50750	CDK9	S1948	S1944F	1944	Missense	distal	-4	no	5.389	5.224	EPSD	TCGA;ICGC	1.932	Down-regulation
CMGC_CDK_CDK9_CDK9_ST	P24928	POLR2A	P50750	CDK9	T1950	S1944F	1944	Missense	distal	-6	no	3.732	3.294	EPSD	TCGA;ICGC	1.932	Down-regulation
CMGC_CDK_CDK9_CDK9_ST	P24928	POLR2A	P50750	CDK9	S1951	S1944F	1944	Missense	distal	-7	no	6.457	6.519	EPSD	TCGA;ICGC	1.932	Up-regulation
CMGC_CDK_CDK9_CDK9_ST	P24928	POLR2A	P50750	CDK9	T1957	I1961M	1961	Missense	distal	4	no	3.835	3.857	EPSD	TCGA;ICGC	1.932	Up-regulation
CMGC_CDK_CDK9_CDK9_ST	P24928	POLR2A	P50750	CDK9	S1958	I1961M	1961	Missense	distal	3	no	6.241	6.278	EPSD	TCGA;ICGC	1.932	Up-regulation
CMGC_CDK_CDK9_CDK9_ST	P24928	POLR2A	P50750	CDK9	S1962	I1961M	1961	Missense	proximal	-1	no	4.945	4.956	EPSD	TCGA;ICGC	1.932	Up-regulation
CMGC_CDK_CDK9_CDK9_ST	Q6PGQ7	BORA	P50750	CDK9	S32	E36A	36	Missense	distal	4	no	2.557	2.545	EPSD	TCGA;ICGC	1.932	Down-regulation
CMGC_CDK_CDK9_CDK9_ST	Q6PGQ7	BORA	P50750	CDK9	S41	E36A	36	Missense	distal	-5	no	4.055	3.986	EPSD	TCGA;ICGC	1.932	Down-regulation
CMGC_CDK_CDK9_CDK9_ST	Q6PGQ7	BORA	P50750	CDK9	S41	F45L	45	Missense	distal	4	no	4.055	4.073	EPSD	TCGA	1.932	Up-regulation
CMGC_CDK_CDK9_CDK9_ST	Q6PGQ7	BORA	P50750	CDK9	T52	R57T	57	Missense	distal	5	no	4.733	4.789	EPSD	TCGA;ICGC	1.932	Up-regulation
CMGC_CDK_CDK9_CDK9_ST	Q6PGQ7	BORA	P50750	CDK9	T52	F45L	45	Missense	distal	-7	no	4.733	4.732	EPSD	TCGA	1.932	Down-regulation
CMGC_CDK_CDK9_CDK9_ST	Q6PGQ7	BORA	P50750	CDK9	S59	I60S	60	Missense	proximal	1	no	0.524	1.938	EPSD	TCGA	1.932	Gain
CMGC_CDK_CDK9_CDK9_ST	Q6PGQ7	BORA	P50750	CDK9	S112	H117N	117	Missense	distal	5	no	3.786	3.938	EPSD	TCGA;ICGC	1.932	Up-regulation
CMGC_CDK_CDK9_CDK9_ST	Q6PGQ7	BORA	P50750	CDK9	T131	C130Y	130	Missense	proximal	-1	no	1.966	1.972	EPSD	TCGA;ICGC	1.932	Up-regulation
CMGC_CDK_CDK9_CDK9_ST	Q6PGQ7	BORA	P50750	CDK9	S137	C130Y	130	Missense	distal	-7	no	5.032	5.023	EPSD	TCGA;ICGC	1.932	Down-regulation
CMGC_CDK_CDK9_CDK9_ST	Q6PGQ7	BORA	P50750	CDK9	S233	S229L	229	Missense	distal	-4	no	4.635	4.480	EPSD	TCGA;ICGC	1.932	Down-regulation
CMGC_CDK_CDK9_CDK9_ST	Q6PGQ7	BORA	P50750	CDK9	S233	D231Y	231	Missense	proximal	-2	no	4.635	4.681	EPSD	TCGA;ICGC	1.932	Up-regulation
CMGC_CDK_CDK9_CDK9_ST	Q6PGQ7	BORA	P50750	CDK9	S239	S246L	246	Missense	distal	7	no	5.729	6.030	EPSD	TCGA;ICGC	1.932	Up-regulation
CMGC_CDK_CDK9_CDK9_ST	Q6PGQ7	BORA	P50750	CDK9	T243	S246L	246	Missense	distal	3	no	3.924	3.613	EPSD	TCGA;ICGC	1.932	Down-regulation
CMGC_CDK_CDK9_CDK9_ST	Q6PGQ7	BORA	P50750	CDK9	S250	S257T	257	Missense	distal	7	no	1.821	2.015	EPSD	TCGA;ICGC	1.932	Gain
CMGC_CDK_CDK9_CDK9_ST	Q6PGQ7	BORA	P50750	CDK9	S252	S257T	257	Missense	distal	5	no	5.464	5.185	EPSD	TCGA;ICGC	1.932	Down-regulation
CMGC_CDK_CDK9_CDK9_ST	Q6PGQ7	BORA	P50750	CDK9	S252	S246L	246	Missense	distal	-6	no	5.464	5.007	EPSD	TCGA;ICGC	1.932	Down-regulation
CMGC_CDK_CDK9_CDK9_ST	Q6PGQ7	BORA	P50750	CDK9	S268	I272V	272	Missense	distal	4	no	5.318	5.310	EPSD	TCGA;ICGC	1.932	Down-regulation
CMGC_CDK_CDK9_CDK9_ST	Q6PGQ7	BORA	P50750	CDK9	S270	I272V	272	Missense	proximal	2	no	6.009	5.994	EPSD	TCGA;ICGC	1.932	Down-regulation
CMGC_CDK_CDK9_CDK9_ST	Q6PGQ7	BORA	P50750	CDK9	S273	I272V	272	Missense	proximal	-1	no	2.776	2.775	EPSD	TCGA;ICGC	1.932	Down-regulation
CMGC_CDK_CDK9_CDK9_ST	Q6PGQ7	BORA	P50750	CDK9	S273	I280T	280	Missense	distal	7	no	2.776	2.682	EPSD	TCGA;ICGC	1.932	Down-regulation
CMGC_CDK_CDK9_CDK9_ST	Q6PGQ7	BORA	P50750	CDK9	S274	I272V	272	Missense	proximal	-2	no	4.856	4.927	EPSD	TCGA;ICGC	1.932	Up-regulation
CMGC_CDK_CDK9_CDK9_ST	Q6PGQ7	BORA	P50750	CDK9	S274	I280T	280	Missense	distal	6	no	4.856	5.087	EPSD	TCGA;ICGC	1.932	Up-regulation
CMGC_CDK_CDK9_CDK9_ST	Q6PGQ7	BORA	P50750	CDK9	S278	I284T	284	Missense	distal	6	no	4.887	5.118	EPSD	TCGA;ICGC	1.932	Up-regulation
CMGC_CDK_CDK9_CDK9_ST	Q6PGQ7	BORA	P50750	CDK9	S278	I272V	272	Missense	distal	-6	no	4.887	4.934	EPSD	TCGA;ICGC	1.932	Up-regulation
CMGC_CDK_CDK9_CDK9_ST	Q6PGQ7	BORA	P50750	CDK9	S278	I280T	280	Missense	proximal	2	no	4.887	4.822	EPSD	TCGA;ICGC	1.932	Down-regulation
CMGC_CDK_CDK9_CDK9_ST	Q6PGQ7	BORA	P50750	CDK9	S299	K294T	294	Missense	distal	-5	no	4.470	4.475	EPSD	TCGA;ICGC	1.932	Up-regulation
CMGC_CDK_CDK9_CDK9_ST	Q6PGQ7	BORA	P50750	CDK9	T306	S308F	308	Missense	proximal	2	no	2.023	2.226	EPSD	TCGA;ICGC	1.932	Up-regulation
CMGC_CDK_CDK9_CDK9_ST	Q6PGQ7	BORA	P50750	CDK9	S308	S308F	308	Missense	central	0	yes	2.550	0.000	EPSD	TCGA;ICGC	1.932	Loss
CMGC_CDK_CDK9_CDK9_ST	Q6PGQ7	BORA	P50750	CDK9	S325	P326S	326	Missense	proximal	1	no	5.008	1.274	PhosphoSitePlus	TCGA;ICGC	1.932	Loss
CMGC_CDK_CDK9_CDK9_ST	Q6PGQ7	BORA	P50750	CDK9	S331	P326S	326	Missense	distal	-5	no	5.706	5.791	EPSD	TCGA;ICGC	1.932	Up-regulation
CMGC_CDK_CDK9_CDK9_ST	Q6PGQ7	BORA	P50750	CDK9	S375	T371K	371	Missense	distal	-4	no	5.530	5.520	EPSD	TCGA;ICGC	1.932	Down-regulation
CMGC_CDK_CDK9_CDK9_ST	Q6PGQ7	BORA	P50750	CDK9	S375	A377T	377	Missense	proximal	2	no	5.530	5.456	EPSD	TCGA;ICGC	1.932	Down-regulation
CMGC_CDK_CDK9_CDK9_ST	Q6PGQ7	BORA	P50750	CDK9	S375	D379N	379	Missense	distal	4	no	5.530	5.592	EPSD	TCGA;ICGC	1.932	Up-regulation
CMGC_CDK_CDK9_CDK9_ST	Q9H0D6	XRN2	P50750	CDK9	T433	I437L	437	Missense	distal	4	no	4.174	4.171	EPSD	TCGA;COSMIC	1.932	Down-regulation
CMGC_CDK_CDK9_CDK9_ST	Q9H0D6	XRN2	P50750	CDK9	T439	I437L	437	Missense	proximal	-2	no	5.819	5.752	PhosphoSitePlus	TCGA;COSMIC	1.932	Down-regulation
CMGC_CDK_CDK9_CDK9_ST	Q9H0D6	XRN2	P50750	CDK9	S448	P449R	449	Missense	proximal	1	no	2.947	-1.229	EPSD	TCGA;COSMIC	1.932	Loss
CMGC_CDK_CDK9_CDK9_ST	Q9H0D6	XRN2	P50750	CDK9	S471	P472L	472	Missense	proximal	1	no	4.531	-1.067	EPSD	TCGA;COSMIC	1.932	Loss
CMGC_CDK_CDK9_CDK9_ST	Q9H0D6	XRN2	P50750	CDK9	S475	S482Y	482	Missense	distal	7	no	5.832	6.121	EPSD	TCGA	1.932	Up-regulation
CMGC_CDK_CDK9_CDK9_ST	Q9H0D6	XRN2	P50750	CDK9	S475	F480L	480	Missense	distal	5	no	5.832	5.864	EPSD	TCGA;COSMIC	1.932	Up-regulation
CMGC_CDK_CDK9_CDK9_ST	Q9H0D6	XRN2	P50750	CDK9	S475	P472L	472	Missense	distal	-3	no	5.832	5.917	EPSD	TCGA;COSMIC	1.932	Up-regulation
CMGC_CDK_CDK9_CDK9_ST	Q9H0D6	XRN2	P50750	CDK9	T481	S482Y	482	Missense	proximal	1	no	2.301	1.522	EPSD	TCGA	1.932	Loss
CMGC_CDK_CDK9_CDK9_ST	Q9H0D6	XRN2	P50750	CDK9	T481	F480L	480	Missense	proximal	-1	no	2.301	2.306	EPSD	TCGA;COSMIC	1.932	Up-regulation
CMGC_CDK_CDK9_CDK9_ST	Q9H0D6	XRN2	P50750	CDK9	T481	S487P	487	Missense	distal	6	no	2.301	2.270	EPSD	TCGA;COSMIC	1.932	Down-regulation
CMGC_CDK_CDK9_CDK9_ST	Q9H0D6	XRN2	P50750	CDK9	S485	S482Y	482	Missense	distal	-3	no	4.367	4.449	EPSD	TCGA	1.932	Up-regulation
CMGC_CDK_CDK9_CDK9_ST	Q9H0D6	XRN2	P50750	CDK9	S485	F480L	480	Missense	distal	-5	no	4.367	4.380	EPSD	TCGA;COSMIC	1.932	Up-regulation
CMGC_CDK_CDK9_CDK9_ST	Q9H0D6	XRN2	P50750	CDK9	S485	S487P	487	Missense	proximal	2	no	4.367	4.405	EPSD	TCGA;COSMIC	1.932	Up-regulation
CMGC_CDK_CDK9_CDK9_ST	Q9H0D6	XRN2	P50750	CDK9	S485	G490A	490	Missense	distal	5	no	4.367	4.296	EPSD	TCGA;COSMIC	1.932	Down-regulation
CMGC_CDK_CDK9_CDK9_ST	Q9H0D6	XRN2	P50750	CDK9	S485	L489S	489	Missense	distal	4	no	4.367	4.502	EPSD	TCGA;COSMIC	1.932	Up-regulation
CMGC_CDK_CDK9_CDK9_ST	Q9H0D6	XRN2	P50750	CDK9	S487	S482Y	482	Missense	distal	-5	no	6.247	5.847	EPSD	TCGA	1.932	Down-regulation
CMGC_CDK_CDK9_CDK9_ST	Q9H0D6	XRN2	P50750	CDK9	S487	S487P	487	Missense	central	0	yes	6.247	0.000	EPSD	TCGA;COSMIC	1.932	Loss
CMGC_CDK_CDK9_CDK9_ST	Q9H0D6	XRN2	P50750	CDK9	S487	G490A	490	Missense	distal	3	no	6.247	6.232	EPSD	TCGA;COSMIC	1.932	Down-regulation
CMGC_CDK_CDK9_CDK9_ST	Q9H0D6	XRN2	P50750	CDK9	S487	L489S	489	Missense	proximal	2	no	6.247	6.045	EPSD	TCGA;COSMIC	1.932	Down-regulation
CMGC_CDK_CDK9_CDK9_ST	Q9H0D6	XRN2	P50750	CDK9	T670	T670I	670	Missense	central	0	yes	4.198	0.000	EPSD	TCGA;COSMIC	1.932	Loss
CMGC_CDK_CDK9_CDK9_ST	Q9H0D6	XRN2	P50750	CDK9	S678	L679P	679	Missense	proximal	1	no	-1.343	4.255	EPSD	TCGA;COSMIC	1.932	Gain
CMGC_CDK_CDK9_CDK9_ST	Q9H0D6	XRN2	P50750	CDK9	S790	R793W	793	Missense	distal	3	no	2.214	2.126	EPSD	TCGA	1.932	Down-regulation
CMGC_CDK_CDK9_CDK9_ST	Q9H0D6	XRN2	P50750	CDK9	S790	S789C	789	Missense	proximal	-1	no	2.214	2.134	EPSD	TCGA;COSMIC	1.932	Down-regulation
CMGC_CDK_CDK9_CDK9_ST	Q9H0D6	XRN2	P50750	CDK9	S790	W786L	786	Missense	distal	-4	no	2.214	2.222	EPSD	TCGA;COSMIC	1.932	Up-regulation
CMGC_CDK_CDK9_CDK9_ST	Q9H0D6	XRN2	P50750	CDK9	S790	P797R	797	Missense	distal	7	no	2.214	2.405	EPSD	TCGA;COSMIC	1.932	Up-regulation
CMGC_CDK_CDK9_CDK9_ST	Q9H0D6	XRN2	P50750	CDK9	S832	Y831C	831	Missense	proximal	-1	no	2.062	2.057	EPSD	TCGA	1.932	Down-regulation
CMGC_CDK_CDK9_CDK9_ST	P37231	PPARG	P50750	CDK9	S112	S117Y	117	Missense	distal	5	no	5.604	5.210	PhosphoSitePlus	TCGA	1.932	Down-regulation
CMGC_CDK_CDK9_CDK9_ST	P37231	PPARG	P50750	CDK9	S273	M280T	280	Missense	distal	7	no	4.027	3.980	EPSD	TCGA;COSMIC	1.932	Down-regulation
CMGC_CDK_CDK9_CDK9_ST	P37231	PPARG	P50750	CDK9	S273	G267E	267	Missense	distal	-6	no	4.027	4.102	EPSD	TCGA	1.932	Up-regulation
CMGC_CDK_CDK9_CDK9_ST	P10275	AR	P50750	CDK9	S96	G95S	95	Missense	proximal	-1	no	4.065	4.127	EPSD	TCGA;ICGC;COSMIC	1.932	Up-regulation
CMGC_CDK_CDK9_CDK9_ST	P10275	AR	P50750	CDK9	S96	E93D	93	Missense	distal	-3	no	4.065	4.085	EPSD	TCGA;ICGC;COSMIC	1.932	Up-regulation
CMGC_CDK_CDK9_CDK9_ST	P10275	AR	P50750	CDK9	S258	R264W	264	Missense	distal	6	no	4.086	3.910	EPSD	TCGA;ICGC;COSMIC	1.932	Down-regulation
CMGC_CDK_CDK9_CDK9_ST	P10275	AR	P50750	CDK9	S258	A253V	253	Missense	distal	-5	no	4.086	4.079	EPSD	TCGA;ICGC;COSMIC	1.932	Down-regulation
CMGC_CDK_CDK9_CDK9_ST	P10275	AR	P50750	CDK9	T282	E289K	289	Missense	distal	7	no	4.856	4.837	EPSD	TCGA;ICGC;COSMIC	1.932	Down-regulation
CMGC_CDK_CDK9_CDK9_ST	P10275	AR	P50750	CDK9	T282	R280C	280	Missense	proximal	-2	no	4.856	4.648	EPSD	TCGA;ICGC;COSMIC	1.932	Down-regulation
CMGC_CDK_CDK9_CDK9_ST	P10275	AR	P50750	CDK9	S310	E308K	308	Missense	proximal	-2	no	4.651	4.720	EPSD	TCGA;COSMIC	1.932	Up-regulation
CMGC_CDK_CDK9_CDK9_ST	P10275	AR	P50750	CDK9	S310	Y316H	316	Missense	distal	6	no	4.651	4.694	EPSD	TCGA;ICGC	1.932	Up-regulation
CMGC_CDK_CDK9_CDK9_ST	P10275	AR	P50750	CDK9	S516	P513S	513	Missense	distal	-3	no	5.379	5.375	EPSD	TCGA;ICGC;COSMIC	1.932	Down-regulation
CMGC_CDK_CDK9_CDK9_ST	P10275	AR	P50750	CDK9	S651	E645K	645	Missense	distal	-6	no	4.953	5.015	EPSD	TCGA;ICGC;COSMIC	1.932	Up-regulation
CMGC_CDK_CDK9_CDK9_ST	P10275	AR	P50750	CDK9	T657	V662L	662	Missense	distal	5	no	2.642	2.624	EPSD	TCGA;ICGC;COSMIC	1.932	Down-regulation
CMGC_CDK_CDK9_CDK9_ST	P10275	AR	P50750	CDK9	T657	T661S	661	Missense	distal	4	no	2.642	2.734	EPSD	TCGA;ICGC	1.932	Up-regulation
CMGC_CDK_CDK9_CDK9_ST	Q15596	NCOA2	P50750	CDK9	S29	G27E	27	Missense	proximal	-2	no	6.112	6.212	EPSD	TCGA;ICGC;COSMIC	1.932	Up-regulation
CMGC_CDK_CDK9_CDK9_ST	Q15596	NCOA2	P50750	CDK9	S29	G27R	27	Missense	proximal	-2	no	6.112	6.226	EPSD	TCGA;ICGC;COSMIC;GDSC	1.932	Up-regulation
CMGC_CDK_CDK9_CDK9_ST	Q15596	NCOA2	P50750	CDK9	S29	P23S	23	Missense	distal	-6	no	6.112	5.980	EPSD	TCGA;ICGC;COSMIC	1.932	Down-regulation
CMGC_CDK_CDK9_CDK9_ST	Q15596	NCOA2	P50750	CDK9	S400	Q406K	406	Missense	distal	6	no	2.325	2.137	EPSD	TCGA;ICGC;COSMIC	1.932	Down-regulation
CMGC_CDK_CDK9_CDK9_ST	Q15596	NCOA2	P50750	CDK9	S400	S399R	399	Missense	proximal	-1	no	2.325	2.269	EPSD	TCGA;ICGC	1.932	Down-regulation
CMGC_CDK_CDK9_CDK9_ST	Q15596	NCOA2	P50750	CDK9	S402	Q406K	406	Missense	distal	4	no	4.947	4.903	EPSD	TCGA;ICGC;COSMIC	1.932	Down-regulation
CMGC_CDK_CDK9_CDK9_ST	Q15596	NCOA2	P50750	CDK9	S402	S399R	399	Missense	distal	-3	no	4.947	5.013	EPSD	TCGA;ICGC	1.932	Up-regulation
CMGC_CDK_CDK9_CDK9_ST	Q15596	NCOA2	P50750	CDK9	S421	P426S	426	Missense	distal	5	no	2.627	2.747	EPSD	TCGA;ICGC;COSMIC	1.932	Up-regulation
CMGC_CDK_CDK9_CDK9_ST	Q15596	NCOA2	P50750	CDK9	S487	R491H	491	Missense	distal	4	no	5.333	5.324	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC;GDSC;CCLE	1.932	Down-regulation
CMGC_CDK_CDK9_CDK9_ST	Q15596	NCOA2	P50750	CDK9	S493	R491H	491	Missense	proximal	-2	no	5.367	5.295	PhosphoSitePlus;EPSD	TCGA;ICGC;COSMIC;GDSC;CCLE	1.932	Down-regulation
CMGC_CDK_CDK9_CDK9_ST	Q15596	NCOA2	P50750	CDK9	S554	K558T	558	Missense	distal	4	no	3.599	3.613	EPSD	TCGA;ICGC	1.932	Up-regulation
CMGC_CDK_CDK9_CDK9_ST	Q15596	NCOA2	P50750	CDK9	S565	S565F	565	Missense	central	0	yes	4.997	0.000	EPSD	TCGA;ICGC;COSMIC	1.932	Loss
CMGC_CDK_CDK9_CDK9_ST	Q15596	NCOA2	P50750	CDK9	S565	M569V	569	Missense	distal	4	no	4.997	4.966	EPSD	TCGA;ICGC;COSMIC	1.932	Down-regulation
CMGC_CDK_CDK9_CDK9_ST	Q15596	NCOA2	P50750	CDK9	S565	P566L	566	Missense	proximal	1	no	4.997	-0.601	EPSD	TCGA;ICGC;COSMIC	1.932	Loss
CMGC_CDK_CDK9_CDK9_ST	Q15596	NCOA2	P50750	CDK9	S565	K558T	558	Missense	distal	-7	no	4.997	4.994	EPSD	TCGA;ICGC	1.932	Down-regulation
CMGC_CDK_CDK9_CDK9_ST	Q15596	NCOA2	P50750	CDK9	S655	S655L	655	Missense	central	0	yes	4.793	0.000	EPSD	TCGA;ICGC;COSMIC	1.932	Loss
CMGC_CDK_CDK9_CDK9_ST	Q15596	NCOA2	P50750	CDK9	S655	M652L	652	Missense	distal	-3	no	4.793	4.812	EPSD	TCGA;ICGC;COSMIC	1.932	Up-regulation
CMGC_CDK_CDK9_CDK9_ST	Q15596	NCOA2	P50750	CDK9	S655	P654A	654	Missense	proximal	-1	no	4.793	4.757	EPSD	TCGA;ICGC;COSMIC	1.932	Down-regulation
CMGC_CDK_CDK9_CDK9_ST	Q15596	NCOA2	P50750	CDK9	S659	S655L	655	Missense	distal	-4	no	2.087	1.933	EPSD	TCGA;ICGC;COSMIC	1.932	Down-regulation
CMGC_CDK_CDK9_CDK9_ST	Q15596	NCOA2	P50750	CDK9	S659	M652L	652	Missense	distal	-7	no	2.087	2.101	EPSD	TCGA;ICGC;COSMIC	1.932	Up-regulation
CMGC_CDK_CDK9_CDK9_ST	Q15596	NCOA2	P50750	CDK9	S659	P654A	654	Missense	distal	-5	no	2.087	1.755	EPSD	TCGA;ICGC;COSMIC	1.932	Loss
CMGC_CDK_CDK9_CDK9_ST	Q15596	NCOA2	P50750	CDK9	T664	S668T	668	Missense	distal	4	no	2.878	2.787	EPSD	TCGA;ICGC;COSMIC	1.932	Down-regulation
CMGC_CDK_CDK9_CDK9_ST	Q15596	NCOA2	P50750	CDK9	S699	D702Y	702	Missense	distal	3	no	4.239	4.280	EPSD	TCGA;ICGC;COSMIC	1.932	Up-regulation
CMGC_CDK_CDK9_CDK9_ST	Q15596	NCOA2	P50750	CDK9	S699	S699F	699	Missense	central	0	yes	4.239	0.000	EPSD	TCGA;ICGC	1.932	Loss
CMGC_CDK_CDK9_CDK9_ST	Q15596	NCOA2	P50750	CDK9	S720	L715V	715	Missense	distal	-5	no	1.924	1.964	EPSD	TCGA;ICGC;COSMIC	1.932	Gain
CMGC_CDK_CDK9_CDK9_ST	Q15596	NCOA2	P50750	CDK9	S721	L715V	715	Missense	distal	-6	no	2.132	2.230	EPSD	TCGA;ICGC;COSMIC	1.932	Up-regulation
CMGC_CDK_CDK9_CDK9_ST	Q15596	NCOA2	P50750	CDK9	S721	S716N	716	Missense	distal	-5	no	2.132	1.903	EPSD	TCGA;ICGC;COSMIC	1.932	Loss
CMGC_CDK_CDK9_CDK9_ST	Q15596	NCOA2	P50750	CDK9	S736	T729A	729	Missense	distal	-7	no	5.598	5.621	EPSD	TCGA;ICGC;COSMIC	1.932	Up-regulation
CMGC_CDK_CDK9_CDK9_ST	Q15596	NCOA2	P50750	CDK9	T763	P760T	760	Missense	distal	-3	no	4.624	4.675	EPSD	TCGA;ICGC;COSMIC	1.932	Up-regulation
CMGC_CDK_CDK9_CDK9_ST	Q15596	NCOA2	P50750	CDK9	S777	P775S	775	Missense	proximal	-2	no	1.996	1.757	EPSD	TCGA;ICGC;COSMIC	1.932	Loss
CMGC_CDK_CDK9_CDK9_ST	Q15596	NCOA2	P50750	CDK9	S851	A848T	848	Missense	distal	-3	no	4.095	4.062	EPSD	TCGA;ICGC;COSMIC	1.932	Down-regulation
CMGC_CDK_CDK9_CDK9_ST	Q15596	NCOA2	P50750	CDK9	T854	A848T	848	Missense	distal	-6	no	6.136	6.297	EPSD	TCGA;ICGC;COSMIC	1.932	Up-regulation
CMGC_CDK_CDK9_CDK9_ST	Q15596	NCOA2	P50750	CDK9	S895	T897N	897	Missense	proximal	2	no	5.047	5.034	EPSD	TCGA;ICGC;COSMIC	1.932	Down-regulation
CMGC_CDK_CDK9_CDK9_ST	Q15596	NCOA2	P50750	CDK9	S895	A899D	899	Missense	distal	4	no	5.047	5.028	EPSD	TCGA;ICGC;COSMIC	1.932	Down-regulation
CMGC_CDK_CDK9_CDK9_ST	Q15596	NCOA2	P50750	CDK9	S1059	G1057D	1057	Missense	proximal	-2	no	5.295	5.268	EPSD	TCGA;ICGC;COSMIC	1.932	Down-regulation
CMGC_CDK_CDK9_CDK9_ST	Q15596	NCOA2	P50750	CDK9	S1072	P1068L	1068	Missense	distal	-4	no	5.249	5.115	EPSD	TCGA;ICGC;COSMIC	1.932	Down-regulation
CMGC_CDK_CDK9_CDK9_ST	Q15596	NCOA2	P50750	CDK9	S1072	A1070S	1070	Missense	proximal	-2	no	5.249	5.711	EPSD	TCGA;ICGC;COSMIC	1.932	Up-regulation
CMGC_CDK_CDK9_CDK9_ST	Q15596	NCOA2	P50750	CDK9	S1072	A1069V	1069	Missense	distal	-3	no	5.249	5.241	EPSD	TCGA;ICGC;COSMIC	1.932	Down-regulation
CMGC_CDK_CDK9_CDK9_ST	Q15596	NCOA2	P50750	CDK9	S1211	L1218F	1218	Missense	distal	7	no	2.248	2.275	EPSD	TCGA;ICGC;COSMIC	1.932	Up-regulation
CMGC_CDK_CDK9_CDK9_ST	Q15596	NCOA2	P50750	CDK9	T1273	M1272T	1272	Missense	proximal	-1	no	4.922	4.931	EPSD	TCGA;ICGC;COSMIC	1.932	Up-regulation
CMGC_CDK_CDK9_CDK9_ST	Q15596	NCOA2	P50750	CDK9	S1287	G1281S	1281	Missense	distal	-6	no	1.762	2.132	EPSD	TCGA;ICGC;COSMIC	1.932	Gain
CMGC_CDK_CDK9_CDK9_ST	P06400	RB1	P50750	CDK9	S230	F226L	226	Missense	distal	-4	no	3.314	3.325	EPSD	TCGA;ICGC;COSMIC	1.932	Up-regulation
CMGC_CDK_CDK9_CDK9_ST	P06400	RB1	P50750	CDK9	S230	Y225C	225	Missense	distal	-5	no	3.314	3.234	EPSD	TCGA;ICGC	1.932	Down-regulation
CMGC_CDK_CDK9_CDK9_ST	P06400	RB1	P50750	CDK9	S249	R255Q	255	Missense	distal	6	no	5.182	5.426	EPSD	TCGA;ICGC;COSMIC	1.932	Up-regulation
CMGC_CDK_CDK9_CDK9_ST	P06400	RB1	P50750	CDK9	S249	R251Q	251	Missense	proximal	2	no	5.182	5.136	EPSD	TCGA;ICGC;COSMIC;CCLE	1.932	Down-regulation
CMGC_CDK_CDK9_CDK9_ST	P06400	RB1	P50750	CDK9	S249	P245A	245	Missense	distal	-4	no	5.182	5.057	EPSD	TCGA;ICGC;COSMIC	1.932	Down-regulation
CMGC_CDK_CDK9_CDK9_ST	P06400	RB1	P50750	CDK9	T252	R255Q	255	Missense	distal	3	no	5.473	5.597	EPSD	TCGA;ICGC;COSMIC	1.932	Up-regulation
CMGC_CDK_CDK9_CDK9_ST	P06400	RB1	P50750	CDK9	T252	R251Q	251	Missense	proximal	-1	no	5.473	5.491	EPSD	TCGA;ICGC;COSMIC;CCLE	1.932	Up-regulation
CMGC_CDK_CDK9_CDK9_ST	P06400	RB1	P50750	CDK9	T252	P245A	245	Missense	distal	-7	no	5.473	5.535	EPSD	TCGA;ICGC;COSMIC	1.932	Up-regulation
CMGC_CDK_CDK9_CDK9_ST	P06400	RB1	P50750	CDK9	T252	R259S	259	Missense	distal	7	no	5.473	5.244	EPSD	TCGA;ICGC;COSMIC	1.932	Down-regulation
CMGC_CDK_CDK9_CDK9_ST	P06400	RB1	P50750	CDK9	T356	S350I	350	Missense	distal	-6	no	4.712	4.306	EPSD	TCGA;ICGC;COSMIC;GDSC	1.932	Down-regulation
CMGC_CDK_CDK9_CDK9_ST	P06400	RB1	P50750	CDK9	T373	P374A	374	Missense	proximal	1	no	4.052	-1.112	EPSD	TCGA;ICGC;COSMIC	1.932	Loss
CMGC_CDK_CDK9_CDK9_ST	P06400	RB1	P50750	CDK9	T373	M379L	379	Missense	distal	6	no	4.052	3.925	EPSD	TCGA;ICGC;COSMIC	1.932	Down-regulation
CMGC_CDK_CDK9_CDK9_ST	P06400	RB1	P50750	CDK9	S567	S567L	567	Missense	central	0	yes	4.316	0.000	EPSD	TCGA;ICGC;COSMIC	1.932	Loss
CMGC_CDK_CDK9_CDK9_ST	P06400	RB1	P50750	CDK9	S567	W563S	563	Missense	distal	-4	no	4.316	4.478	EPSD	TCGA;ICGC;COSMIC	1.932	Up-regulation
CMGC_CDK_CDK9_CDK9_ST	P06400	RB1	P50750	CDK9	S567	A562E	562	Missense	distal	-5	no	4.316	4.385	EPSD	TCGA;ICGC;COSMIC	1.932	Up-regulation
CMGC_CDK_CDK9_CDK9_ST	P06400	RB1	P50750	CDK9	S608	D604G	604	Missense	distal	-4	no	4.435	4.467	EPSD	TCGA;ICGC;COSMIC	1.932	Up-regulation
CMGC_CDK_CDK9_CDK9_ST	P06400	RB1	P50750	CDK9	S780	I782M	782	Missense	proximal	2	no	5.296	5.274	EPSD	TCGA;ICGC;COSMIC	1.932	Down-regulation
CMGC_CDK_CDK9_CDK9_ST	P06400	RB1	P50750	CDK9	S780	R787Q	787	Missense	distal	7	no	5.296	5.200	EPSD	TCGA;ICGC;COSMIC	1.932	Down-regulation
CMGC_CDK_CDK9_CDK9_ST	P06400	RB1	P50750	CDK9	S788	I782M	782	Missense	distal	-6	no	5.074	5.138	EPSD	TCGA;ICGC;COSMIC	1.932	Up-regulation
CMGC_CDK_CDK9_CDK9_ST	P06400	RB1	P50750	CDK9	S788	S788N	788	Missense	central	0	yes	5.074	0.000	EPSD	TCGA;ICGC;COSMIC	1.932	Loss
CMGC_CDK_CDK9_CDK9_ST	P06400	RB1	P50750	CDK9	S788	R787Q	787	Missense	proximal	-1	no	5.074	5.092	EPSD	TCGA;ICGC;COSMIC	1.932	Up-regulation
CMGC_CDK_CDK9_CDK9_ST	P06400	RB1	P50750	CDK9	S794	S788N	788	Missense	distal	-6	no	2.098	1.954	EPSD	TCGA;ICGC;COSMIC	1.932	Down-regulation
CMGC_CDK_CDK9_CDK9_ST	P06400	RB1	P50750	CDK9	S794	R798W	798	Missense	distal	4	no	2.098	2.062	EPSD	TCGA;ICGC;COSMIC;GDSC	1.932	Down-regulation
CMGC_CDK_CDK9_CDK9_ST	P06400	RB1	P50750	CDK9	S794	R787Q	787	Missense	distal	-7	no	2.098	2.081	EPSD	TCGA;ICGC;COSMIC	1.932	Down-regulation
CMGC_CDK_CDK9_CDK9_ST	P06400	RB1	P50750	CDK9	S795	S788N	788	Missense	distal	-7	no	5.687	5.712	PhosphoSitePlus;EPSD	TCGA;ICGC;COSMIC	1.932	Up-regulation
CMGC_CDK_CDK9_CDK9_ST	P06400	RB1	P50750	CDK9	S795	R798W	798	Missense	distal	3	no	5.687	5.599	PhosphoSitePlus;EPSD	TCGA;ICGC;COSMIC;GDSC	1.932	Down-regulation
CMGC_CDK_CDK9_CDK9_ST	P06400	RB1	P50750	CDK9	S807	N803S	803	Missense	distal	-4	no	4.492	4.566	EPSD;PhosphoSitePlus	TCGA;ICGC	1.932	Up-regulation
CMGC_CDK_CDK9_CDK9_ST	P06400	RB1	P50750	CDK9	T821	P827S	827	Missense	distal	6	no	4.624	4.655	EPSD	TCGA;ICGC;COSMIC	1.932	Up-regulation
CMGC_CDK_CDK9_CDK9_ST	P06400	RB1	P50750	CDK9	T826	P827S	827	Missense	proximal	1	no	4.640	0.906	EPSD	TCGA;ICGC;COSMIC	1.932	Loss
CMGC_CDK_CDK9_CDK9_ST	P06400	RB1	P50750	CDK9	S866	G865V	865	Missense	proximal	-1	no	2.057	2.049	EPSD	TCGA;ICGC;COSMIC	1.932	Down-regulation
CMGC_CDK_CDK9_CDK9_ST	P06400	RB1	P50750	CDK9	S866	K860R	860	Missense	distal	-6	no	2.057	2.003	EPSD	TCGA;ICGC;COSMIC	1.932	Down-regulation
CMGC_CDK_CDK9_CDK9_ST	P06400	RB1	P50750	CDK9	T905	Q912R	912	Missense	distal	7	no	2.236	2.332	EPSD	TCGA;ICGC	1.932	Up-regulation
CMGC_CDK_CDK9_CDK9_ST	P24928	POLR2A	P50750	CDK9	T1540	A1543T	1543	Missense	distal	3	no	3.803	3.891	PhosphoSitePlus	TCGA;ICGC	1.932	Up-regulation
CMGC_CDK_CDK9_CDK9_ST	P04637	TP53	P50750	CDK9	S33	P27S	27	Missense	distal	-6	no	5.662	5.530	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	1.932	Down-regulation
CMGC_CDK_CDK9_CDK9_ST	P04637	TP53	P50750	CDK9	S33	P27L	27	Missense	distal	-6	no	5.662	5.073	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC;GDSC;CCLE	1.932	Down-regulation
CMGC_CDK_CDK9_CDK9_ST	P04637	TP53	P50750	CDK9	S46	D48N	48	Missense	proximal	2	no	4.557	4.473	EPSD	TCGA;ICGC;COSMIC;GDSC;CCLE	1.932	Down-regulation
CMGC_CDK_CDK9_CDK9_ST	P04637	TP53	P50750	CDK9	T81	A79V	79	Missense	proximal	-2	no	4.981	5.031	EPSD	TCGA;ICGC;COSMIC	1.932	Up-regulation
CMGC_CDK_CDK9_CDK9_ST	P04637	TP53	P50750	CDK9	T81	P77L	77	Missense	distal	-4	no	4.981	4.846	EPSD	TCGA;ICGC;COSMIC	1.932	Down-regulation
CMGC_CDK_CDK9_CDK9_ST	P04637	TP53	P50750	CDK9	T81	P82L	82	Missense	proximal	1	no	4.981	-0.618	EPSD	TCGA;ICGC;COSMIC	1.932	Loss
CMGC_CDK_CDK9_CDK9_ST	P04637	TP53	P50750	CDK9	T81	A74T	74	Missense	distal	-7	no	4.981	4.958	EPSD	TCGA;ICGC;COSMIC	1.932	Down-regulation
CMGC_CDK_CDK9_CDK9_ST	P04637	TP53	P50750	CDK9	S127	K132N	132	Missense	distal	5	no	4.849	4.930	EPSD	TCGA;ICGC;COSMIC;GDSC;CCLE	1.932	Up-regulation
CMGC_CDK_CDK9_CDK9_ST	P04637	TP53	P50750	CDK9	S127	S121Y	121	Missense	distal	-6	no	4.849	4.494	EPSD	TCGA;ICGC;COSMIC	1.932	Down-regulation
CMGC_CDK_CDK9_CDK9_ST	P04637	TP53	P50750	CDK9	S127	M133K	133	Missense	distal	6	no	4.849	4.957	EPSD	TCGA;ICGC;COSMIC;CCLE	1.932	Up-regulation
CMGC_CDK_CDK9_CDK9_ST	P04637	TP53	P50750	CDK9	S127	K132E	132	Missense	distal	5	no	4.849	4.795	EPSD	TCGA;ICGC;COSMIC;GDSC;CCLE	1.932	Down-regulation
CMGC_CDK_CDK9_CDK9_ST	P04637	TP53	P50750	CDK9	S127	Y126C	126	Missense	proximal	-1	no	4.849	4.844	EPSD	TCGA;ICGC;COSMIC;GDSC	1.932	Down-regulation
CMGC_CDK_CDK9_CDK9_ST	P04637	TP53	P50750	CDK9	S127	S127P	127	Missense	central	0	yes	4.849	0.000	EPSD	TCGA;ICGC;COSMIC;GDSC;CCLE	1.932	Loss
CMGC_CDK_CDK9_CDK9_ST	P04637	TP53	P50750	CDK9	S127	Y126N	126	Missense	proximal	-1	no	4.849	4.878	EPSD	TCGA;ICGC;COSMIC	1.932	Up-regulation
CMGC_CDK_CDK9_CDK9_ST	P04637	TP53	P50750	CDK9	S127	L130V	130	Missense	distal	3	no	4.849	4.907	EPSD	TCGA;ICGC;COSMIC;GDSC;CCLE	1.932	Up-regulation
CMGC_CDK_CDK9_CDK9_ST	P04637	TP53	P50750	CDK9	S127	K132T	132	Missense	distal	5	no	4.849	4.872	EPSD	TCGA;ICGC;COSMIC;GDSC;CCLE	1.932	Up-regulation
CMGC_CDK_CDK9_CDK9_ST	P04637	TP53	P50750	CDK9	S127	S127Y	127	Missense	central	0	yes	4.849	0.000	EPSD	TCGA;ICGC;COSMIC	1.932	Loss
CMGC_CDK_CDK9_CDK9_ST	P04637	TP53	P50750	CDK9	S127	S127F	127	Missense	central	0	yes	4.849	0.000	EPSD	TCGA;ICGC;COSMIC;CCLE	1.932	Loss
CMGC_CDK_CDK9_CDK9_ST	P04637	TP53	P50750	CDK9	S127	M133R	133	Missense	distal	6	no	4.849	4.900	EPSD	TCGA;ICGC;COSMIC	1.932	Up-regulation
CMGC_CDK_CDK9_CDK9_ST	P04637	TP53	P50750	CDK9	S127	K132R	132	Missense	distal	5	no	4.849	4.816	EPSD	TCGA;ICGC;COSMIC;GDSC;CCLE	1.932	Down-regulation
CMGC_CDK_CDK9_CDK9_ST	P04637	TP53	P50750	CDK9	S127	F134L	134	Missense	distal	7	no	4.849	4.822	EPSD	TCGA;ICGC;COSMIC;CCLE	1.932	Down-regulation
CMGC_CDK_CDK9_CDK9_ST	P04637	TP53	P50750	CDK9	S127	Y126S	126	Missense	proximal	-1	no	4.849	4.924	EPSD	TCGA;ICGC;COSMIC	1.932	Up-regulation
CMGC_CDK_CDK9_CDK9_ST	P04637	TP53	P50750	CDK9	S127	L130P	130	Missense	distal	3	no	4.849	5.195	EPSD	TCGA;ICGC;COSMIC	1.932	Up-regulation
CMGC_CDK_CDK9_CDK9_ST	P04637	TP53	P50750	CDK9	S127	L130F	130	Missense	distal	3	no	4.849	4.857	EPSD	TCGA;ICGC;COSMIC;CCLE	1.932	Up-regulation
CMGC_CDK_CDK9_CDK9_ST	P04637	TP53	P50750	CDK9	S127	F134V	134	Missense	distal	7	no	4.849	4.805	EPSD	TCGA;ICGC;COSMIC	1.932	Down-regulation
CMGC_CDK_CDK9_CDK9_ST	P04637	TP53	P50750	CDK9	S127	T125M	125	Missense	proximal	-2	no	4.849	4.707	EPSD	TCGA;ICGC;COSMIC;GDSC	1.932	Down-regulation
CMGC_CDK_CDK9_CDK9_ST	P04637	TP53	P50750	CDK9	S127	K120E	120	Missense	distal	-7	no	4.849	4.854	EPSD	TCGA;ICGC;COSMIC	1.932	Up-regulation
CMGC_CDK_CDK9_CDK9_ST	P04637	TP53	P50750	CDK9	S127	N131S	131	Missense	distal	4	no	4.849	4.932	EPSD	TCGA;ICGC;COSMIC	1.932	Up-regulation
CMGC_CDK_CDK9_CDK9_ST	P04637	TP53	P50750	CDK9	S127	T125P	125	Missense	proximal	-2	no	4.849	5.341	EPSD	TCGA;ICGC;COSMIC;CCLE	1.932	Up-regulation
CMGC_CDK_CDK9_CDK9_ST	P04637	TP53	P50750	CDK9	S127	S127C	127	Missense	central	0	yes	4.849	0.000	EPSD	TCGA;ICGC;COSMIC;CCLE	1.932	Loss
CMGC_CDK_CDK9_CDK9_ST	P04637	TP53	P50750	CDK9	S127	N131I	131	Missense	distal	4	no	4.849	4.801	EPSD	TCGA;ICGC;COSMIC	1.932	Down-regulation
CMGC_CDK_CDK9_CDK9_ST	P04637	TP53	P50750	CDK9	S127	Y126H	126	Missense	proximal	-1	no	4.849	4.864	EPSD	TCGA;ICGC;COSMIC;GDSC	1.932	Up-regulation
CMGC_CDK_CDK9_CDK9_ST	P04637	TP53	P50750	CDK9	S127	K132Q	132	Missense	distal	5	no	4.849	4.992	EPSD	TCGA;ICGC;COSMIC;GDSC;CCLE	1.932	Up-regulation
CMGC_CDK_CDK9_CDK9_ST	P04637	TP53	P50750	CDK9	S127	L130R	130	Missense	distal	3	no	4.849	4.956	EPSD	TCGA;ICGC;COSMIC;CCLE	1.932	Up-regulation
CMGC_CDK_CDK9_CDK9_ST	P04637	TP53	P50750	CDK9	T150	W146S	146	Missense	distal	-4	no	5.274	5.436	EPSD	TCGA;ICGC;COSMIC	1.932	Up-regulation
CMGC_CDK_CDK9_CDK9_ST	P04637	TP53	P50750	CDK9	T150	P152L	152	Missense	proximal	2	no	5.274	5.439	EPSD	TCGA;ICGC;COSMIC;GDSC;CCLE	1.932	Up-regulation
CMGC_CDK_CDK9_CDK9_ST	P04637	TP53	P50750	CDK9	T150	D148N	148	Missense	proximal	-2	no	5.274	5.606	EPSD	TCGA;ICGC;COSMIC	1.932	Up-regulation
CMGC_CDK_CDK9_CDK9_ST	P04637	TP53	P50750	CDK9	T150	P151H	151	Missense	proximal	1	no	5.274	0.700	EPSD	TCGA;ICGC;COSMIC;GDSC;CCLE	1.932	Loss
CMGC_CDK_CDK9_CDK9_ST	P04637	TP53	P50750	CDK9	T150	P151A	151	Missense	proximal	1	no	5.274	0.110	EPSD	TCGA;ICGC;COSMIC;CCLE	1.932	Loss
CMGC_CDK_CDK9_CDK9_ST	P04637	TP53	P50750	CDK9	T150	R156P	156	Missense	distal	6	no	5.274	5.701	EPSD	TCGA;ICGC;COSMIC;GDSC;CCLE	1.932	Up-regulation
CMGC_CDK_CDK9_CDK9_ST	P04637	TP53	P50750	CDK9	T150	V143A	143	Missense	distal	-7	no	5.274	5.279	EPSD	TCGA;ICGC;COSMIC;GDSC;CCLE	1.932	Up-regulation
CMGC_CDK_CDK9_CDK9_ST	P04637	TP53	P50750	CDK9	T150	P151S	151	Missense	proximal	1	no	5.274	1.540	EPSD	TCGA;ICGC;COSMIC;GDSC;CCLE	1.932	Loss
CMGC_CDK_CDK9_CDK9_ST	P04637	TP53	P50750	CDK9	T150	V157F	157	Missense	distal	7	no	5.274	5.319	EPSD	TCGA;ICGC;COSMIC;GDSC;CCLE	1.932	Up-regulation
CMGC_CDK_CDK9_CDK9_ST	P04637	TP53	P50750	CDK9	T150	V157G	157	Missense	distal	7	no	5.274	5.260	EPSD	TCGA;ICGC;COSMIC	1.932	Down-regulation
CMGC_CDK_CDK9_CDK9_ST	P04637	TP53	P50750	CDK9	T150	V157D	157	Missense	distal	7	no	5.274	5.290	EPSD	TCGA;ICGC;COSMIC	1.932	Up-regulation
CMGC_CDK_CDK9_CDK9_ST	P04637	TP53	P50750	CDK9	T150	L145R	145	Missense	distal	-5	no	5.274	5.409	EPSD	TCGA;ICGC;COSMIC;GDSC;CCLE	1.932	Up-regulation
CMGC_CDK_CDK9_CDK9_ST	P04637	TP53	P50750	CDK9	T150	T155I	155	Missense	distal	5	no	5.274	5.136	EPSD	TCGA;ICGC;COSMIC;CCLE	1.932	Down-regulation
CMGC_CDK_CDK9_CDK9_ST	P04637	TP53	P50750	CDK9	T150	V143M	143	Missense	distal	-7	no	5.274	5.269	EPSD	TCGA;ICGC;COSMIC;GDSC;CCLE	1.932	Down-regulation
CMGC_CDK_CDK9_CDK9_ST	P04637	TP53	P50750	CDK9	T150	T155N	155	Missense	distal	5	no	5.274	5.333	EPSD	TCGA;ICGC;COSMIC;GDSC;CCLE	1.932	Up-regulation
CMGC_CDK_CDK9_CDK9_ST	P04637	TP53	P50750	CDK9	T150	P152S	152	Missense	proximal	2	no	5.274	5.237	EPSD	TCGA;ICGC;COSMIC;CCLE	1.932	Down-regulation
CMGC_CDK_CDK9_CDK9_ST	P04637	TP53	P50750	CDK9	T150	R156C	156	Missense	distal	6	no	5.274	5.061	EPSD	TCGA;ICGC;COSMIC	1.932	Down-regulation
CMGC_CDK_CDK9_CDK9_ST	P04637	TP53	P50750	CDK9	T150	P151T	151	Missense	proximal	1	no	5.274	1.255	EPSD	TCGA;ICGC;COSMIC	1.932	Loss
CMGC_CDK_CDK9_CDK9_ST	P04637	TP53	P50750	CDK9	T150	T155P	155	Missense	distal	5	no	5.274	5.433	EPSD	TCGA;ICGC;COSMIC;CCLE	1.932	Up-regulation
CMGC_CDK_CDK9_CDK9_ST	P04637	TP53	P50750	CDK9	T150	P152Q	152	Missense	proximal	2	no	5.274	5.333	EPSD	TCGA;ICGC;COSMIC	1.932	Up-regulation
CMGC_CDK_CDK9_CDK9_ST	P04637	TP53	P50750	CDK9	T150	R156H	156	Missense	distal	6	no	5.274	5.224	EPSD	TCGA;ICGC;COSMIC	1.932	Down-regulation
CMGC_CDK_CDK9_CDK9_ST	P04637	TP53	P50750	CDK9	T150	L145P	145	Missense	distal	-5	no	5.274	5.653	EPSD	TCGA;ICGC;COSMIC	1.932	Up-regulation
CMGC_CDK_CDK9_CDK9_ST	P04637	TP53	P50750	CDK9	T150	Q144L	144	Missense	distal	-6	no	5.274	4.936	EPSD	TCGA;ICGC;COSMIC	1.932	Down-regulation
CMGC_CDK_CDK9_CDK9_ST	P04637	TP53	P50750	CDK9	T150	Q144H	144	Missense	distal	-6	no	5.274	5.064	EPSD	TCGA;ICGC;COSMIC	1.932	Down-regulation
CMGC_CDK_CDK9_CDK9_ST	P04637	TP53	P50750	CDK9	T150	G154V	154	Missense	distal	4	no	5.274	5.232	EPSD	TCGA;ICGC;COSMIC;GDSC;CCLE	1.932	Down-regulation
CMGC_CDK_CDK9_CDK9_ST	P04637	TP53	P50750	CDK9	T150	V157L	157	Missense	distal	7	no	5.274	5.291	EPSD	TCGA;ICGC;COSMIC	1.932	Up-regulation
CMGC_CDK_CDK9_CDK9_ST	P04637	TP53	P50750	CDK9	T150	P151R	151	Missense	proximal	1	no	5.274	1.098	EPSD	TCGA;ICGC;COSMIC	1.932	Loss
CMGC_CDK_CDK9_CDK9_ST	P04637	TP53	P50750	CDK9	T150	Q144P	144	Missense	distal	-6	no	5.274	5.526	EPSD	TCGA;ICGC;COSMIC	1.932	Up-regulation
CMGC_CDK_CDK9_CDK9_ST	P04637	TP53	P50750	CDK9	T150	V143E	143	Missense	distal	-7	no	5.274	5.263	EPSD	TCGA;ICGC;COSMIC	1.932	Down-regulation
CMGC_CDK_CDK9_CDK9_ST	P04637	TP53	P50750	CDK9	T150	R156G	156	Missense	distal	6	no	5.274	5.222	EPSD	TCGA;ICGC;COSMIC	1.932	Down-regulation
CMGC_CDK_CDK9_CDK9_ST	P04637	TP53	P50750	CDK9	T150	P151L	151	Missense	proximal	1	no	5.274	-0.324	EPSD	TCGA;ICGC;COSMIC	1.932	Loss
CMGC_CDK_CDK9_CDK9_ST	P04637	TP53	P50750	CDK9	T155	A161S	161	Missense	distal	6	no	1.591	2.140	EPSD	TCGA;ICGC;COSMIC	1.932	Gain
CMGC_CDK_CDK9_CDK9_ST	P04637	TP53	P50750	CDK9	T155	R156P	156	Missense	proximal	1	no	1.591	5.767	EPSD	TCGA;ICGC;COSMIC;GDSC;CCLE	1.932	Gain
CMGC_CDK_CDK9_CDK9_ST	P04637	TP53	P50750	CDK9	T155	A161P	161	Missense	distal	6	no	1.591	2.109	EPSD	TCGA;ICGC;COSMIC	1.932	Gain
CMGC_CDK_CDK9_CDK9_ST	P04637	TP53	P50750	CDK9	T312	K319N	319	Missense	distal	7	no	2.262	2.191	EPSD	TCGA;ICGC;COSMIC	1.932	Down-regulation
CMGC_CDK_CDK9_CDK9_ST	P04637	TP53	P50750	CDK9	T312	A307V	307	Missense	distal	-5	no	2.262	2.255	EPSD	TCGA;ICGC;COSMIC;GDSC	1.932	Down-regulation
CMGC_CDK_CDK9_CDK9_ST	P04637	TP53	P50750	CDK9	T312	S315C	315	Missense	distal	3	no	2.262	1.958	EPSD	TCGA;ICGC;COSMIC	1.932	Down-regulation
CMGC_CDK_CDK9_CDK9_ST	P04637	TP53	P50750	CDK9	S313	K319N	319	Missense	distal	6	no	2.130	2.282	EPSD	TCGA;ICGC;COSMIC	1.932	Up-regulation
CMGC_CDK_CDK9_CDK9_ST	P04637	TP53	P50750	CDK9	S313	A307V	307	Missense	distal	-6	no	2.130	2.167	EPSD	TCGA;ICGC;COSMIC;GDSC	1.932	Up-regulation
CMGC_CDK_CDK9_CDK9_ST	P04637	TP53	P50750	CDK9	S313	K320E	320	Missense	distal	7	no	2.130	2.149	EPSD	TCGA;ICGC;COSMIC	1.932	Up-regulation
CMGC_CDK_CDK9_CDK9_ST	P04637	TP53	P50750	CDK9	S313	S315C	315	Missense	proximal	2	no	2.130	2.338	EPSD	TCGA;ICGC;COSMIC	1.932	Up-regulation
CMGC_CDK_CDK9_CDK9_ST	P04637	TP53	P50750	CDK9	S315	K319N	319	Missense	distal	4	no	5.402	5.425	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	1.932	Up-regulation
CMGC_CDK_CDK9_CDK9_ST	P04637	TP53	P50750	CDK9	S315	K320E	320	Missense	distal	5	no	5.402	5.348	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	1.932	Down-regulation
CMGC_CDK_CDK9_CDK9_ST	P04637	TP53	P50750	CDK9	S315	S315C	315	Missense	central	0	yes	5.402	0.000	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	1.932	Loss
CMGC_CDK_CDK9_CDK9_ST	P04637	TP53	P50750	CDK9	T377	S376C	376	Missense	proximal	-1	no	2.722	2.642	EPSD	TCGA;ICGC;COSMIC	1.932	Down-regulation
CMGC_CDK_CDK9_CDK9_ST	P04637	TP53	P50750	CDK9	T377	Q375K	375	Missense	proximal	-2	no	2.722	2.571	EPSD	TCGA;ICGC;COSMIC	1.932	Down-regulation
CMGC_CDK_CDK9_CDK9_ST	P04637	TP53	P50750	CDK9	S378	S376C	376	Missense	proximal	-2	no	2.329	1.804	EPSD	TCGA;ICGC;COSMIC	1.932	Loss
CMGC_CDK_CDK9_CDK9_ST	P04637	TP53	P50750	CDK9	S378	Q375K	375	Missense	distal	-3	no	2.329	2.344	EPSD	TCGA;ICGC;COSMIC	1.932	Up-regulation
CAMK_CAMKL_MELK_MELK_ST	Q14680	MELK	Q14680	MELK	T56	R53L	53	Missense	distal	-3	no	244.425	213.105	EPSD;PhosphoSitePlus	TCGA;COSMIC	155.919	Down-regulation
CAMK_CAMKL_MELK_MELK_ST	Q14680	MELK	Q14680	MELK	S253	K249N	249	Missense	distal	-4	no	226.646	226.249	EPSD;PhosphoSitePlus	TCGA;CCLE	155.919	Down-regulation
CAMK_CAMKL_MELK_MELK_ST	Q14680	MELK	Q14680	MELK	S253	D247G	247	Missense	distal	-6	no	226.646	234.293	EPSD;PhosphoSitePlus	TCGA;COSMIC	155.919	Up-regulation
CAMK_CAMKL_MELK_MELK_ST	Q14680	MELK	Q14680	MELK	S253	L257I	257	Missense	distal	4	no	226.646	223.860	EPSD;PhosphoSitePlus	TCGA;COSMIC	155.919	Down-regulation
CAMK_CAMKL_MELK_MELK_ST	Q14680	MELK	Q14680	MELK	S336	R331C	331	Missense	distal	-5	no	246.493	237.237	EPSD;PhosphoSitePlus	TCGA;COSMIC	155.919	Down-regulation
CAMK_CAMKL_MELK_MELK_ST	Q14680	MELK	Q14680	MELK	S336	R331H	331	Missense	distal	-5	no	246.493	238.155	EPSD;PhosphoSitePlus	TCGA;COSMIC	155.919	Down-regulation
CAMK_CAMKL_MELK_MELK_ST	Q14680	MELK	Q14680	MELK	T387	T383S	383	Missense	distal	-4	no	211.694	213.400	EPSD;PhosphoSitePlus	TCGA;COSMIC	155.919	Up-regulation
CAMK_CAMKL_MELK_MELK_ST	Q14680	MELK	Q14680	MELK	T387	T390I	390	Missense	distal	3	no	211.694	227.999	EPSD;PhosphoSitePlus	TCGA;COSMIC	155.919	Up-regulation
CAMK_CAMKL_MELK_MELK_ST	Q14680	MELK	Q14680	MELK	S391	T390I	390	Missense	proximal	-1	no	225.428	246.812	EPSD;PhosphoSitePlus	TCGA;COSMIC	155.919	Up-regulation
CAMK_CAMKL_MELK_MELK_ST	Q14680	MELK	Q14680	MELK	S431	T428A	428	Missense	distal	-3	no	216.244	216.800	EPSD;PhosphoSitePlus	TCGA;COSMIC	155.919	Up-regulation
CAMK_CAMKL_MELK_MELK_ST	Q14680	MELK	Q14680	MELK	S431	E424D	424	Missense	distal	-7	no	216.244	222.542	EPSD;PhosphoSitePlus	TCGA;COSMIC	155.919	Up-regulation
CAMK_CAMKL_MELK_MELK_ST	Q14680	MELK	Q14680	MELK	T494	R501M	501	Missense	distal	7	no	236.319	204.869	EPSD;PhosphoSitePlus	TCGA	155.919	Down-regulation
CAMK_CAMKL_MELK_MELK_ST	Q14680	MELK	Q14680	MELK	S505	V506A	506	Missense	proximal	1	no	229.693	230.712	EPSD;PhosphoSitePlus	TCGA;COSMIC	155.919	Up-regulation
CAMK_CAMKL_MELK_MELK_ST	Q14680	MELK	Q14680	MELK	S505	E507K	507	Missense	proximal	2	no	229.693	227.268	EPSD;PhosphoSitePlus	TCGA;COSMIC	155.919	Down-regulation
CAMK_CAMKL_MELK_MELK_ST	Q14680	MELK	Q14680	MELK	S505	R502Q	502	Missense	distal	-3	no	229.693	195.998	EPSD;PhosphoSitePlus	TCGA	155.919	Down-regulation
CAMK_CAMKL_MELK_MELK_ST	Q14680	MELK	Q14680	MELK	S505	R504C	504	Missense	proximal	-1	no	229.693	228.981	EPSD;PhosphoSitePlus	TCGA;COSMIC	155.919	Down-regulation
CAMK_CAMKL_MELK_MELK_ST	Q14680	MELK	Q14680	MELK	S505	R504H	504	Missense	proximal	-1	no	229.693	235.387	EPSD;PhosphoSitePlus	TCGA;COSMIC	155.919	Up-regulation
CAMK_CAMKL_MELK_MELK_ST	Q14680	MELK	Q14680	MELK	S505	R501M	501	Missense	distal	-4	no	229.693	230.647	EPSD;PhosphoSitePlus	TCGA	155.919	Up-regulation
CAMK_CAMKL_MELK_MELK_ST	Q14680	MELK	Q14680	MELK	S505	L510I	510	Missense	distal	5	no	229.693	204.338	EPSD;PhosphoSitePlus	TCGA;COSMIC	155.919	Down-regulation
CAMK_CAMKL_MELK_MELK_ST	P30305	CDC25B	Q14680	MELK	S91	R92Q	92	Missense	proximal	1	no	158.041	160.903	EPSD	TCGA;COSMIC	155.919	Up-regulation
CAMK_CAMKL_MELK_MELK_ST	P30305	CDC25B	Q14680	MELK	S91	S89Y	89	Missense	proximal	-2	no	158.041	158.862	EPSD	TCGA;COSMIC	155.919	Up-regulation
CAMK_CAMKL_MELK_MELK_ST	P30305	CDC25B	Q14680	MELK	S91	E96K	96	Missense	distal	5	no	158.041	157.422	EPSD	TCGA;COSMIC	155.919	Down-regulation
CAMK_CAMKL_MELK_MELK_ST	P30305	CDC25B	Q14680	MELK	S91	R84H	84	Missense	distal	-7	no	158.041	139.724	EPSD	TCGA;COSMIC	155.919	Loss
CAMK_CAMKL_MELK_MELK_ST	P30305	CDC25B	Q14680	MELK	S160	P153L	153	Missense	distal	-7	no	148.702	164.321	EPSD	TCGA;ICGC;COSMIC	155.919	Gain
CAMK_CAMKL_MELK_MELK_ST	P30305	CDC25B	Q14680	MELK	S169	V162M	162	Missense	distal	-7	no	213.004	195.996	PhosphoSitePlus;EPSD	TCGA;ICGC;COSMIC	155.919	Down-regulation
CAMK_CAMKL_MELK_MELK_ST	P30305	CDC25B	Q14680	MELK	S169	R164Q	164	Missense	distal	-5	no	213.004	212.687	PhosphoSitePlus;EPSD	TCGA	155.919	Down-regulation
CAMK_CAMKL_MELK_MELK_ST	P30305	CDC25B	Q14680	MELK	S323	R317Q	317	Missense	distal	-6	no	225.877	231.226	EPSD;PhosphoSitePlus	TCGA;COSMIC	155.919	Up-regulation
CAMK_CAMKL_MELK_MELK_ST	P30305	CDC25B	Q14680	MELK	S470	E464D	464	Missense	distal	-6	no	156.622	152.397	EPSD	TCGA;ICGC	155.919	Loss
CAMK_CAMKL_MELK_MELK_ST	P30305	CDC25B	Q14680	MELK	S470	A463V	463	Missense	distal	-7	no	156.622	170.189	EPSD	TCGA;ICGC;COSMIC	155.919	Up-regulation
CAMK_CAMKL_MELK_MELK_ST	P30305	CDC25B	Q14680	MELK	S563	R568W	568	Missense	distal	5	no	165.448	142.726	EPSD	TCGA;COSMIC	155.919	Loss
CAMK_CAMKL_MELK_MELK_ST	P30305	CDC25B	Q14680	MELK	S563	R562H	562	Missense	proximal	-1	no	165.448	171.142	EPSD	TCGA;COSMIC;CCLE	155.919	Up-regulation
CAMK_CAMKL_MELK_MELK_ST	P23588	EIF4B	Q14680	MELK	S57	D50H	50	Missense	distal	-7	no	170.173	152.505	EPSD	TCGA;ICGC;COSMIC	155.919	Loss
CAMK_CAMKL_MELK_MELK_ST	P23588	EIF4B	Q14680	MELK	S57	D60N	60	Missense	distal	3	no	170.173	169.422	EPSD	TCGA;ICGC;COSMIC	155.919	Down-regulation
CAMK_CAMKL_MELK_MELK_ST	P23588	EIF4B	Q14680	MELK	S71	A65V	65	Missense	distal	-6	no	161.869	152.365	EPSD	TCGA;ICGC;COSMIC;CCLE	155.919	Loss
CAMK_CAMKL_MELK_MELK_ST	P23588	EIF4B	Q14680	MELK	S276	D271N	271	Missense	distal	-5	no	161.934	171.820	EPSD	TCGA;COSMIC	155.919	Up-regulation
CAMK_CAMKL_MELK_MELK_ST	P23588	EIF4B	Q14680	MELK	S276	G275C	275	Missense	proximal	-1	no	161.934	151.793	EPSD	TCGA	155.919	Loss
CAMK_CAMKL_MELK_MELK_ST	P23588	EIF4B	Q14680	MELK	S311	D314V	314	Missense	distal	3	no	165.366	164.789	EPSD	TCGA;COSMIC	155.919	Down-regulation
CAMK_CAMKL_MELK_MELK_ST	P23588	EIF4B	Q14680	MELK	S311	R308Q	308	Missense	distal	-3	no	165.366	131.671	EPSD	TCGA;COSMIC	155.919	Loss
CAMK_CAMKL_MELK_MELK_ST	P23588	EIF4B	Q14680	MELK	S311	D314H	314	Missense	distal	3	no	165.366	173.787	EPSD	TCGA;COSMIC	155.919	Up-regulation
CAMK_CAMKL_MELK_MELK_ST	P23588	EIF4B	Q14680	MELK	S311	R318Q	318	Missense	distal	7	no	165.366	158.641	EPSD	TCGA;COSMIC	155.919	Down-regulation
CAMK_CAMKL_MELK_MELK_ST	P23588	EIF4B	Q14680	MELK	S311	S309P	309	Missense	proximal	-2	no	165.366	160.706	EPSD	TCGA;COSMIC	155.919	Down-regulation
CAMK_CAMKL_MELK_MELK_ST	P23588	EIF4B	Q14680	MELK	S311	R305Q	305	Missense	distal	-6	no	165.366	170.715	EPSD	TCGA;COSMIC	155.919	Up-regulation
CAMK_CAMKL_MELK_MELK_ST	P23588	EIF4B	Q14680	MELK	S406	R408Q	408	Missense	proximal	2	no	239.515	228.361	PhosphoSitePlus;EPSD	TCGA;COSMIC	155.919	Down-regulation
CAMK_CAMKL_MELK_MELK_ST	P23588	EIF4B	Q14680	MELK	S406	R401W	401	Missense	distal	-5	no	239.515	224.739	PhosphoSitePlus;EPSD	TCGA;COSMIC	155.919	Down-regulation
CAMK_CAMKL_MELK_MELK_ST	P23588	EIF4B	Q14680	MELK	S418	R417W	417	Missense	proximal	-1	no	140.266	157.539	EPSD	TCGA;COSMIC	155.919	Gain
CAMK_CAMKL_MELK_MELK_ST	P23588	EIF4B	Q14680	MELK	S422	R415L	415	Missense	distal	-7	no	213.941	202.006	EPSD;PhosphoSitePlus	TCGA;COSMIC	155.919	Down-regulation
CAMK_CAMKL_MELK_MELK_ST	P23588	EIF4B	Q14680	MELK	S422	R417W	417	Missense	distal	-5	no	213.941	199.164	EPSD;PhosphoSitePlus	TCGA;COSMIC	155.919	Down-regulation
CAMK_CAMKL_MELK_MELK_ST	P23588	EIF4B	Q14680	MELK	S424	R417W	417	Missense	distal	-7	no	172.050	146.084	EPSD	TCGA;COSMIC	155.919	Loss
CAMK_CAMKL_MELK_MELK_ST	P23588	EIF4B	Q14680	MELK	S442	A437V	437	Missense	distal	-5	no	161.394	155.823	EPSD	TCGA;COSMIC	155.919	Loss
CAMK_CAMKL_MELK_MELK_ST	P23588	EIF4B	Q14680	MELK	S442	R438Q	438	Missense	distal	-4	no	161.394	160.748	EPSD	TCGA;COSMIC	155.919	Down-regulation
CAMK_CAMKL_MELK_MELK_ST	P23588	EIF4B	Q14680	MELK	S442	S445Y	445	Missense	distal	3	no	161.394	154.686	EPSD	TCGA	155.919	Loss
STE_STE7_MEK1_MAP2K1_ST	Q13148	TARDBP	Q02750	MAP2K1	S254	D247N	247	Missense	distal	-7	no	69.759	69.205	EPSD	TCGA;ICGC;COSMIC	68.590	Down-regulation
STE_STE7_MEK1_MAP2K1_ST	Q13148	TARDBP	Q02750	MAP2K1	S292	G288E	288	Missense	distal	-4	no	90.763	89.939	EPSD	TCGA;COSMIC	68.590	Down-regulation
STE_STE7_MEK1_MAP2K1_ST	Q13148	TARDBP	Q02750	MAP2K1	S292	R293T	293	Missense	proximal	1	no	90.763	85.997	EPSD	TCGA;COSMIC	68.590	Down-regulation
STE_STE7_MEK1_MAP2K1_ST	Q13148	TARDBP	Q02750	MAP2K1	S305	G304S	304	Missense	proximal	-1	no	107.891	113.077	EPSD	TCGA;COSMIC	68.590	Up-regulation
STE_STE7_MEK1_MAP2K1_ST	Q13148	TARDBP	Q02750	MAP2K1	S407	S407C	407	Missense	central	0	yes	73.129	0.000	EPSD	TCGA;COSMIC	68.590	Loss
STE_STE7_MEK1_MAP2K1_ST	Q13148	TARDBP	Q02750	MAP2K1	S410	S407C	407	Missense	distal	-3	no	76.397	76.133	EPSD	TCGA;COSMIC	68.590	Down-regulation
STE_STE7_MEK1_MAP2K1_ST	P28482	MAPK1	Q02750	MAP2K1	T185	D179G	179	Missense	distal	-6	no	151.746	151.986	PhosphoSitePlus;EPSD	TCGA	68.590	Up-regulation
STE_STE7_MEK1_MAP2K1_ST	P28482	MAPK1	Q02750	MAP2K1	T185	R191C	191	Missense	distal	6	no	151.746	149.765	PhosphoSitePlus;EPSD	TCGA;ICGC;COSMIC	68.590	Down-regulation
STE_STE7_MEK1_MAP2K1_ST	P28482	MAPK1	Q02750	MAP2K1	T185	R191H	191	Missense	distal	6	no	151.746	150.902	PhosphoSitePlus;EPSD	TCGA;ICGC;COSMIC	68.590	Down-regulation
STE_STE7_MEK1_MAP2K1_ST	P28482	MAPK1	Q02750	MAP2K1	T190	R191C	191	Missense	proximal	1	no	118.072	125.706	EPSD	TCGA;ICGC;COSMIC	68.590	Up-regulation
STE_STE7_MEK1_MAP2K1_ST	P28482	MAPK1	Q02750	MAP2K1	T190	R191H	191	Missense	proximal	1	no	118.072	117.486	EPSD	TCGA;ICGC;COSMIC	68.590	Down-regulation
STE_STE7_MEK1_MAP2K1_ST	P27361	MAPK3	Q02750	MAP2K1	T207	R211W	211	Missense	distal	4	no	117.682	115.168	EPSD;PhosphoSitePlus	TCGA	68.590	Down-regulation
STE_STE7_MEK1_MAP2K1_ST	P27361	MAPK3	Q02750	MAP2K1	T207	E214D	214	Missense	distal	7	no	117.682	117.675	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	68.590	Down-regulation
STE_STE7_MEK1_MAP2K1_ST	P49841	GSK3B	Q02750	MAP2K1	S25	Q19R	19	Missense	distal	-6	no	84.801	84.478	EPSD	TCGA	68.590	Down-regulation
STE_STE7_MEK1_MAP2K1_ST	P49841	GSK3B	Q02750	MAP2K1	S25	S25N	25	Missense	central	0	yes	84.801	0.000	EPSD	TCGA;ICGC	68.590	Loss
STE_STE7_MEK1_MAP2K1_ST	P49841	GSK3B	Q02750	MAP2K1	S25	A22S	22	Missense	distal	-3	no	84.801	84.660	EPSD	TCGA;ICGC	68.590	Down-regulation
STE_STE7_MEK1_MAP2K1_ST	P05787	KRT8	Q02750	MAP2K1	S9	S15F	15	Missense	distal	6	no	76.274	76.053	EPSD	TCGA;ICGC;COSMIC	68.590	Down-regulation
STE_STE7_MEK1_MAP2K1_ST	P05787	KRT8	Q02750	MAP2K1	S37	S37F	37	Missense	central	0	yes	69.115	0.000	EPSD	TCGA;ICGC;COSMIC	68.590	Loss
STE_STE7_MEK1_MAP2K1_ST	Q00613	HSF1	Q02750	MAP2K1	S290	R296C	296	Missense	distal	6	no	70.764	68.783	EPSD	TCGA;COSMIC	68.590	Down-regulation
STE_STE7_MEK1_MAP2K1_ST	Q00613	HSF1	Q02750	MAP2K1	S290	P288L	288	Missense	proximal	-2	no	70.764	69.450	EPSD	TCGA;COSMIC	68.590	Down-regulation
STE_STE7_MEK1_MAP2K1_ST	Q00613	HSF1	Q02750	MAP2K1	S290	E286K	286	Missense	distal	-4	no	70.764	64.677	EPSD	TCGA;COSMIC	68.590	Loss
STE_STE7_MEK1_MAP2K1_ST	Q00613	HSF1	Q02750	MAP2K1	S291	R296C	296	Missense	distal	5	no	77.443	76.767	EPSD	TCGA;COSMIC	68.590	Down-regulation
STE_STE7_MEK1_MAP2K1_ST	Q00613	HSF1	Q02750	MAP2K1	S291	P288L	288	Missense	distal	-3	no	77.443	82.057	EPSD	TCGA;COSMIC	68.590	Up-regulation
STE_STE7_MEK1_MAP2K1_ST	Q00613	HSF1	Q02750	MAP2K1	S291	E286K	286	Missense	distal	-5	no	77.443	76.919	EPSD	TCGA;COSMIC	68.590	Down-regulation
STE_STE7_MEK1_MAP2K1_ST	Q00613	HSF1	Q02750	MAP2K1	S292	R296C	296	Missense	distal	4	no	86.996	83.660	EPSD	TCGA;COSMIC	68.590	Down-regulation
STE_STE7_MEK1_MAP2K1_ST	Q00613	HSF1	Q02750	MAP2K1	S292	P288L	288	Missense	distal	-4	no	86.996	81.400	EPSD	TCGA;COSMIC	68.590	Down-regulation
STE_STE7_MEK1_MAP2K1_ST	Q00613	HSF1	Q02750	MAP2K1	S292	E286K	286	Missense	distal	-6	no	86.996	86.616	EPSD	TCGA;COSMIC	68.590	Down-regulation
STE_STE7_MEK1_MAP2K1_ST	Q00613	HSF1	Q02750	MAP2K1	S314	R317H	317	Missense	distal	3	no	68.744	70.706	EPSD	TCGA;COSMIC	68.590	Up-regulation
STE_STE7_MEK1_MAP2K1_ST	Q00613	HSF1	Q02750	MAP2K1	S314	S320F	320	Missense	distal	6	no	68.744	68.522	EPSD	TCGA;COSMIC	68.590	Loss
STE_STE7_MEK1_MAP2K1_ST	Q00613	HSF1	Q02750	MAP2K1	S326	D332Y	332	Missense	distal	6	no	134.037	135.357	PhosphoSitePlus	TCGA;COSMIC	68.590	Up-regulation
STE_STE7_MEK1_MAP2K1_ST	Q00613	HSF1	Q02750	MAP2K1	S326	T323I	323	Missense	distal	-3	no	134.037	134.884	PhosphoSitePlus	TCGA;COSMIC	68.590	Up-regulation
STE_STE7_MEK1_MAP2K1_ST	Q00613	HSF1	Q02750	MAP2K1	S326	S320F	320	Missense	distal	-6	no	134.037	133.999	PhosphoSitePlus	TCGA;COSMIC	68.590	Down-regulation
STE_STE7_MEK1_MAP2K1_ST	Q00613	HSF1	Q02750	MAP2K1	S326	A329T	329	Missense	distal	3	no	134.037	134.917	PhosphoSitePlus	TCGA;COSMIC	68.590	Up-regulation
STE_STE7_MEK1_MAP2K1_ST	Q00613	HSF1	Q02750	MAP2K1	S326	S333F	333	Missense	distal	7	no	134.037	134.011	PhosphoSitePlus	TCGA;COSMIC	68.590	Down-regulation
STE_STE7_MEK1_MAP2K1_ST	Q00613	HSF1	Q02750	MAP2K1	S326	P327L	327	Missense	proximal	1	no	134.037	119.550	PhosphoSitePlus	TCGA	68.590	Down-regulation
STE_STE7_MEK1_MAP2K1_ST	Q00613	HSF1	Q02750	MAP2K1	T328	P327L	327	Missense	proximal	-1	no	59.254	84.758	EPSD	TCGA	68.590	Gain
STE_STE7_MEK1_MAP2K1_ST	Q00613	HSF1	Q02750	MAP2K1	S338	D332Y	332	Missense	distal	-6	no	77.009	76.546	EPSD	TCGA;COSMIC	68.590	Down-regulation
STE_STE7_MEK1_MAP2K1_ST	Q00613	HSF1	Q02750	MAP2K1	S338	E339G	339	Missense	proximal	1	no	77.009	85.583	EPSD	TCGA;COSMIC	68.590	Up-regulation
STE_STE7_MEK1_MAP2K1_ST	Q00613	HSF1	Q02750	MAP2K1	S338	S333F	333	Missense	distal	-5	no	77.009	77.261	EPSD	TCGA;COSMIC	68.590	Up-regulation
STE_STE7_MEK1_MAP2K1_ST	Q00613	HSF1	Q02750	MAP2K1	S444	E441K	441	Missense	distal	-3	no	66.039	70.133	EPSD	TCGA;COSMIC	68.590	Gain
STE_STE7_MEK1_MAP2K1_ST	P04049	RAF1	Q02750	MAP2K1	T258	S257L	257	Missense	proximal	-1	no	63.586	72.285	EPSD	TCGA;COSMIC;GDSC;CCLE	68.590	Gain
STE_STE7_MEK1_MAP2K1_ST	P04049	RAF1	Q02750	MAP2K1	S259	S257L	257	Missense	proximal	-2	no	86.342	88.152	EPSD	TCGA;COSMIC;GDSC;CCLE	68.590	Up-regulation
STE_STE7_MEK1_MAP2K1_ST	P04049	RAF1	Q02750	MAP2K1	S259	P261R	261	Missense	proximal	2	no	86.342	86.517	EPSD	TCGA;COSMIC;CCLE	68.590	Up-regulation
STE_STE7_MEK1_MAP2K1_ST	P04049	RAF1	Q02750	MAP2K1	S259	S257W	257	Missense	proximal	-2	no	86.342	86.561	EPSD	TCGA;COSMIC	68.590	Up-regulation
STE_STE7_MEK1_MAP2K1_ST	P04049	RAF1	Q02750	MAP2K1	S259	S259F	259	Missense	central	0	yes	86.342	0.000	EPSD	TCGA;COSMIC;GDSC;CCLE	68.590	Loss
STE_STE7_MEK1_MAP2K1_ST	P04049	RAF1	Q02750	MAP2K1	S259	H264Y	264	Missense	distal	5	no	86.342	86.981	EPSD	TCGA;COSMIC	68.590	Up-regulation
STE_STE7_MEK1_MAP2K1_ST	P04049	RAF1	Q02750	MAP2K1	T268	P261R	261	Missense	distal	-7	no	68.866	71.793	EPSD	TCGA;COSMIC;CCLE	68.590	Up-regulation
STE_STE7_MEK1_MAP2K1_ST	P04049	RAF1	Q02750	MAP2K1	T268	H264Y	264	Missense	distal	-4	no	68.866	60.303	EPSD	TCGA;COSMIC	68.590	Loss
STE_STE7_MEK1_MAP2K1_ST	P04049	RAF1	Q02750	MAP2K1	S338	R333H	333	Missense	distal	-5	no	137.395	137.865	PhosphoSitePlus	TCGA;COSMIC	68.590	Up-regulation
STE_STE7_MEK1_MAP2K1_ST	P04049	RAF1	Q02750	MAP2K1	S338	S339I	339	Missense	proximal	1	no	137.395	135.043	PhosphoSitePlus	TCGA	68.590	Down-regulation
STE_STE7_MEK1_MAP2K1_ST	P04049	RAF1	Q02750	MAP2K1	S642	P646L	646	Missense	distal	4	no	99.481	96.732	EPSD	TCGA;COSMIC	68.590	Down-regulation
AGC_GRK_GRK_GRK4_ST	P32298	GRK4	P32298	GRK4	S10	E4Q	4	Missense	distal	-6	no	15.694	15.610	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	10.085	Down-regulation
AGC_GRK_GRK_GRK4_ST	P32298	GRK4	P32298	GRK4	S10	A15V	15	Missense	distal	5	no	15.694	15.505	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	10.085	Down-regulation
AGC_GRK_GRK_GRK4_ST	P32298	GRK4	P32298	GRK4	S244	S244N	244	Missense	central	0	yes	17.613	0.000	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC;GDSC;CCLE	10.085	Loss
AGC_GRK_GRK_GRK4_ST	P32298	GRK4	P32298	GRK4	S244	R237I	237	Missense	distal	-7	no	17.613	17.674	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC;GDSC;CCLE	10.085	Up-regulation
AGC_GRK_GRK_GRK4_ST	P32298	GRK4	P32298	GRK4	S244	V247A	247	Missense	distal	3	no	17.613	17.544	EPSD;PhosphoSitePlus	TCGA;ICGC	10.085	Down-regulation
AGC_GRK_GRK_GRK4_ST	P32298	GRK4	P32298	GRK4	S249	S244N	244	Missense	distal	-5	no	21.200	21.262	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC;GDSC;CCLE	10.085	Up-regulation
AGC_GRK_GRK_GRK4_ST	P32298	GRK4	P32298	GRK4	S249	V247A	247	Missense	proximal	-2	no	21.200	21.198	EPSD;PhosphoSitePlus	TCGA;ICGC	10.085	Down-regulation
AGC_GRK_GRK_GRK4_ST	P32298	GRK4	P32298	GRK4	T256	L262V	262	Missense	distal	6	no	17.867	17.528	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	10.085	Down-regulation
AGC_GRK_GRK_GRK4_ST	P32298	GRK4	P32298	GRK4	S485	F484L	484	Missense	proximal	-1	no	19.229	18.698	EPSD;PhosphoSitePlus	TCGA;ICGC	10.085	Down-regulation
AGC_GRK_GRK_GRK4_ST	P30411	BDKRB2	P32298	GRK4	S366	E364D	364	Missense	proximal	-2	no	17.238	17.236	PhosphoSitePlus;EPSD	TCGA;ICGC;COSMIC	10.085	Down-regulation
AGC_GRK_GRK_GRK4_ST	P30411	BDKRB2	P32298	GRK4	S373	R378C	378	Missense	distal	5	no	15.602	16.021	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	10.085	Up-regulation
AGC_GRK_GRK_GRK4_ST	P30411	BDKRB2	P32298	GRK4	S373	S375F	375	Missense	proximal	2	no	15.602	16.432	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	10.085	Up-regulation
AGC_GRK_GRK_GRK4_ST	P30411	BDKRB2	P32298	GRK4	S375	R378C	378	Missense	distal	3	no	14.245	13.881	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	10.085	Down-regulation
AGC_GRK_GRK_GRK4_ST	P30411	BDKRB2	P32298	GRK4	S375	S375F	375	Missense	central	0	yes	14.245	0.000	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	10.085	Loss
CAMK_CAMKL_QIK_SIK2_ST	P27986	PIK3R1	Q9H0K1	SIK2	S43	F42V	42	Missense	proximal	-1	no	1.583	1.546	EPSD	TCGA;ICGC	1.318	Down-regulation
CAMK_CAMKL_QIK_SIK2_ST	P27986	PIK3R1	Q9H0K1	SIK2	S154	S147L	147	Missense	distal	-7	no	2.370	2.323	PhosphoSitePlus;EPSD	TCGA;ICGC;COSMIC	1.318	Down-regulation
CAMK_CAMKL_QIK_SIK2_ST	P27986	PIK3R1	Q9H0K1	SIK2	S154	L149P	149	Missense	distal	-5	no	2.370	2.218	PhosphoSitePlus;EPSD	TCGA	1.318	Down-regulation
CAMK_CAMKL_QIK_SIK2_ST	P27986	PIK3R1	Q9H0K1	SIK2	S156	L149P	149	Missense	distal	-7	no	1.570	1.573	EPSD	TCGA	1.318	Up-regulation
CAMK_CAMKL_QIK_SIK2_ST	P27986	PIK3R1	Q9H0K1	SIK2	S208	A201V	201	Missense	distal	-7	no	1.448	1.428	EPSD	TCGA;ICGC	1.318	Down-regulation
CAMK_CAMKL_QIK_SIK2_ST	P27986	PIK3R1	Q9H0K1	SIK2	S208	S204C	204	Missense	distal	-4	no	1.448	1.431	EPSD	TCGA;ICGC;COSMIC	1.318	Down-regulation
CAMK_CAMKL_QIK_SIK2_ST	P27986	PIK3R1	Q9H0K1	SIK2	S208	S208Y	208	Missense	central	0	yes	1.448	0.000	EPSD	TCGA;ICGC;COSMIC	1.318	Loss
CAMK_CAMKL_QIK_SIK2_ST	P27986	PIK3R1	Q9H0K1	SIK2	S208	V202I	202	Missense	distal	-6	no	1.448	1.518	EPSD	TCGA;ICGC;COSMIC	1.318	Up-regulation
CAMK_CAMKL_QIK_SIK2_ST	P27986	PIK3R1	Q9H0K1	SIK2	S460	D464V	464	Missense	distal	4	no	1.252	1.451	EPSD	TCGA;COSMIC	1.318	Gain
CAMK_CAMKL_QIK_SIK2_ST	P27986	PIK3R1	Q9H0K1	SIK2	S541	R534Q	534	Missense	distal	-7	no	2.328	2.306	EPSD;PhosphoSitePlus	TCGA;COSMIC	1.318	Down-regulation
CAMK_CAMKL_QIK_SIK2_ST	P27986	PIK3R1	Q9H0K1	SIK2	S541	E546Q	546	Missense	distal	5	no	2.328	2.322	EPSD;PhosphoSitePlus	TCGA;COSMIC	1.318	Down-regulation
CAMK_CAMKL_QIK_SIK2_ST	Q9H0K1	SIK2	Q9H0K1	SIK2	S90	Q84L	84	Missense	distal	-6	no	2.301	2.320	PhosphoSitePlus;EPSD	TCGA;ICGC;COSMIC	1.318	Up-regulation
CAMK_CAMKL_QIK_SIK2_ST	Q9H0K1	SIK2	Q9H0K1	SIK2	S342	R336H	336	Missense	distal	-6	no	1.460	1.538	EPSD	TCGA;ICGC;COSMIC	1.318	Up-regulation
CAMK_CAMKL_QIK_SIK2_ST	Q9H0K1	SIK2	Q9H0K1	SIK2	S343	R336H	336	Missense	distal	-7	no	2.296	2.275	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	1.318	Down-regulation
CAMK_CAMKL_QIK_SIK2_ST	Q9H0K1	SIK2	Q9H0K1	SIK2	S358	R356W	356	Missense	proximal	-2	no	2.172	2.144	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	1.318	Down-regulation
CAMK_CAMKL_QIK_SIK2_ST	Q9H0K1	SIK2	Q9H0K1	SIK2	S358	Q354H	354	Missense	distal	-4	no	2.172	2.170	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	1.318	Down-regulation
CAMK_CAMKL_QIK_SIK2_ST	Q9H0K1	SIK2	Q9H0K1	SIK2	S512	D518Y	518	Missense	distal	6	no	1.363	1.443	EPSD	TCGA;ICGC;COSMIC	1.318	Up-regulation
CAMK_CAMKL_QIK_SIK2_ST	Q9H0K1	SIK2	Q9H0K1	SIK2	S512	M519T	519	Missense	distal	7	no	1.363	1.423	EPSD	TCGA;ICGC;COSMIC	1.318	Up-regulation
CAMK_CAMKL_QIK_SIK2_ST	Q9H0K1	SIK2	Q9H0K1	SIK2	S512	D511Y	511	Missense	proximal	-1	no	1.363	1.378	EPSD	TCGA;ICGC;COSMIC	1.318	Up-regulation
CAMK_CAMKL_QIK_SIK2_ST	Q9H0K1	SIK2	Q9H0K1	SIK2	S534	M539V	539	Missense	distal	5	no	1.498	1.558	EPSD	TCGA;ICGC;COSMIC	1.318	Up-regulation
CAMK_CAMKL_QIK_SIK2_ST	Q9H0K1	SIK2	Q9H0K1	SIK2	S545	M539V	539	Missense	distal	-6	no	1.465	1.398	EPSD	TCGA;ICGC;COSMIC	1.318	Down-regulation
CAMK_CAMKL_QIK_SIK2_ST	Q9H0K1	SIK2	Q9H0K1	SIK2	S545	N542D	542	Missense	distal	-3	no	1.465	1.459	EPSD	TCGA;ICGC;COSMIC	1.318	Down-regulation
CAMK_CAMKL_QIK_SIK2_ST	Q15078	CDK5R1	Q9H0K1	SIK2	S91	K87Q	87	Missense	distal	-4	no	2.436	2.429	PhosphoSitePlus	TCGA;ICGC	1.318	Down-regulation
CAMK_CAMKL_QIK_SIK2_ST	Q15078	CDK5R1	Q9H0K1	SIK2	S91	E84D	84	Missense	distal	-7	no	2.436	2.423	PhosphoSitePlus	TCGA;ICGC	1.318	Down-regulation
CAMK_CAMKL_QIK_SIK2_ST	Q15078	CDK5R1	Q9H0K1	SIK2	S263	S263C	263	Missense	central	0	yes	1.333	0.000	EPSD	TCGA;ICGC;COSMIC	1.318	Loss
CAMK_CAMKL_QIK_SIK2_ST	Q9BV73	CEP250	Q9H0K1	SIK2	S45	Q46R	46	Missense	proximal	1	no	1.457	1.459	EPSD	TCGA;ICGC;COSMIC	1.318	Up-regulation
CAMK_CAMKL_QIK_SIK2_ST	Q9BV73	CEP250	Q9H0K1	SIK2	S460	S460F	460	Missense	central	0	yes	1.330	0.000	EPSD	TCGA;ICGC;COSMIC	1.318	Loss
CAMK_CAMKL_QIK_SIK2_ST	Q9BV73	CEP250	Q9H0K1	SIK2	S462	S460F	460	Missense	proximal	-2	no	1.338	1.206	EPSD	TCGA;ICGC;COSMIC	1.318	Loss
CAMK_CAMKL_QIK_SIK2_ST	Q9BV73	CEP250	Q9H0K1	SIK2	S1060	E1065K	1065	Missense	distal	5	no	1.658	1.645	EPSD	TCGA;COSMIC	1.318	Down-regulation
CAMK_CAMKL_QIK_SIK2_ST	Q9BV73	CEP250	Q9H0K1	SIK2	S1060	T1058A	1058	Missense	proximal	-2	no	1.658	1.604	EPSD	TCGA;COSMIC	1.318	Down-regulation
CAMK_CAMKL_QIK_SIK2_ST	Q9BV73	CEP250	Q9H0K1	SIK2	S1060	A1055V	1055	Missense	distal	-5	no	1.658	1.707	EPSD	TCGA;COSMIC	1.318	Up-regulation
CAMK_CAMKL_QIK_SIK2_ST	Q9BV73	CEP250	Q9H0K1	SIK2	S1372	A1374D	1374	Missense	proximal	2	no	1.347	1.341	EPSD	TCGA;COSMIC	1.318	Down-regulation
CAMK_CAMKL_QIK_SIK2_ST	Q9BV73	CEP250	Q9H0K1	SIK2	S1372	V1365I	1365	Missense	distal	-7	no	1.347	1.338	EPSD	TCGA;GDSC;CCLE	1.318	Down-regulation
CAMK_CAMKL_QIK_SIK2_ST	Q9BV73	CEP250	Q9H0K1	SIK2	S1618	E1615K	1615	Missense	distal	-3	no	1.510	1.543	EPSD	TCGA;COSMIC	1.318	Up-regulation
CAMK_CAMKL_QIK_SIK2_ST	Q9BV73	CEP250	Q9H0K1	SIK2	S1691	G1696S	1696	Missense	distal	5	no	1.453	1.626	EPSD	TCGA;COSMIC	1.318	Up-regulation
CAMK_CAMKL_QIK_SIK2_ST	Q9BV73	CEP250	Q9H0K1	SIK2	S1691	G1696D	1696	Missense	distal	5	no	1.453	1.522	EPSD	TCGA;COSMIC	1.318	Up-regulation
CAMK_CAMKL_QIK_SIK2_ST	Q9BV73	CEP250	Q9H0K1	SIK2	S1774	E1777D	1777	Missense	distal	3	no	1.308	1.323	EPSD	TCGA;COSMIC	1.318	Gain
CAMK_CAMKL_QIK_SIK2_ST	Q9BV73	CEP250	Q9H0K1	SIK2	S1800	E1807K	1807	Missense	distal	7	no	1.355	1.320	EPSD	TCGA;COSMIC	1.318	Down-regulation
CAMK_CAMKL_QIK_SIK2_ST	Q9BV73	CEP250	Q9H0K1	SIK2	S1800	Q1802K	1802	Missense	proximal	2	no	1.355	1.362	EPSD	TCGA;COSMIC	1.318	Up-regulation
CAMK_CAMKL_QIK_SIK2_ST	Q9BV73	CEP250	Q9H0K1	SIK2	S1803	E1807K	1807	Missense	distal	4	no	1.658	1.486	EPSD	TCGA;COSMIC	1.318	Down-regulation
CAMK_CAMKL_QIK_SIK2_ST	Q9BV73	CEP250	Q9H0K1	SIK2	S1803	R1810T	1810	Missense	distal	7	no	1.658	1.667	EPSD	TCGA;COSMIC	1.318	Up-regulation
CAMK_CAMKL_QIK_SIK2_ST	Q9BV73	CEP250	Q9H0K1	SIK2	S1803	Q1802K	1802	Missense	proximal	-1	no	1.658	1.636	EPSD	TCGA;COSMIC	1.318	Down-regulation
CAMK_CAMKL_QIK_SIK2_ST	Q9BV73	CEP250	Q9H0K1	SIK2	S1927	A1933T	1933	Missense	distal	6	no	1.181	1.420	EPSD	TCGA;COSMIC	1.318	Gain
CAMK_CAMKL_QIK_SIK2_ST	Q9BV73	CEP250	Q9H0K1	SIK2	S2095	E2088D	2088	Missense	distal	-7	no	1.453	1.440	EPSD	TCGA;COSMIC	1.318	Down-regulation
CAMK_CAMKL_QIK_SIK2_ST	Q9BV73	CEP250	Q9H0K1	SIK2	S2095	H2093Y	2093	Missense	proximal	-2	no	1.453	1.469	EPSD	TCGA;COSMIC	1.318	Up-regulation
CAMK_CAMKL_QIK_SIK2_ST	Q9BV73	CEP250	Q9H0K1	SIK2	S2095	G2091D	2091	Missense	distal	-4	no	1.453	1.489	EPSD	TCGA	1.318	Up-regulation
CAMK_CAMKL_QIK_SIK2_ST	Q9BV73	CEP250	Q9H0K1	SIK2	S2095	Q2094R	2094	Missense	proximal	-1	no	1.453	1.413	EPSD	TCGA;COSMIC	1.318	Down-regulation
CAMK_CAMKL_QIK_SIK2_ST	Q9BV73	CEP250	Q9H0K1	SIK2	S2229	E2223D	2223	Missense	distal	-6	no	1.640	1.674	EPSD	TCGA	1.318	Up-regulation
CAMK_CAMKL_QIK_SIK2_ST	Q9BV73	CEP250	Q9H0K1	SIK2	S2390	A2385T	2385	Missense	distal	-5	no	1.500	1.442	EPSD	TCGA;COSMIC	1.318	Down-regulation
CAMK_CAMKL_QIK_SIK2_ST	Q9BV73	CEP250	Q9H0K1	SIK2	S2390	G2386C	2386	Missense	distal	-4	no	1.500	1.535	EPSD	TCGA	1.318	Up-regulation
CAMK_CAMKL_QIK_SIK2_ST	Q9BV73	CEP250	Q9H0K1	SIK2	S2392	A2385T	2385	Missense	distal	-7	no	2.291	2.316	PhosphoSitePlus;EPSD	TCGA;COSMIC	1.318	Up-regulation
CAMK_CAMKL_QIK_SIK2_ST	Q9BV73	CEP250	Q9H0K1	SIK2	S2392	A2399V	2399	Missense	distal	7	no	2.291	2.288	PhosphoSitePlus;EPSD	TCGA	1.318	Down-regulation
CAMK_CAMKL_QIK_SIK2_ST	Q9BV73	CEP250	Q9H0K1	SIK2	S2392	G2386C	2386	Missense	distal	-6	no	2.291	2.250	PhosphoSitePlus;EPSD	TCGA	1.318	Down-regulation
CAMK_CAMKL_QIK_SIK2_ST	Q9BV73	CEP250	Q9H0K1	SIK2	S2392	A2399S	2399	Missense	distal	7	no	2.291	2.316	PhosphoSitePlus;EPSD	TCGA;COSMIC	1.318	Up-regulation
CAMK_CAMKL_QIK_SIK2_ST	Q9BV73	CEP250	Q9H0K1	SIK2	S2394	A2399V	2399	Missense	distal	5	no	2.292	2.215	EPSD;PhosphoSitePlus	TCGA	1.318	Down-regulation
CAMK_CAMKL_QIK_SIK2_ST	Q9BV73	CEP250	Q9H0K1	SIK2	S2394	A2399S	2399	Missense	distal	5	no	2.292	2.265	EPSD;PhosphoSitePlus	TCGA;COSMIC	1.318	Down-regulation
CAMK_CAMKL_QIK_SIK2_ST	Q9BV73	CEP250	Q9H0K1	SIK2	S2394	A2399T	2399	Missense	distal	5	no	2.292	2.222	EPSD;PhosphoSitePlus	TCGA;COSMIC	1.318	Down-regulation
CAMK_CAMKL_QIK_SIK2_ST	Q9BV73	CEP250	Q9H0K1	SIK2	S2417	S2421N	2421	Missense	distal	4	no	1.680	1.720	EPSD	TCGA	1.318	Up-regulation
CAMK_CAMKL_QIK_SIK2_ST	Q9BV73	CEP250	Q9H0K1	SIK2	S2435	P2434L	2434	Missense	proximal	-1	no	1.343	1.367	EPSD	TCGA;COSMIC	1.318	Up-regulation
CAMK_CAMKL_QIK_SIK2_ST	Q9BV73	CEP250	Q9H0K1	SIK2	S2435	S2433R	2433	Missense	proximal	-2	no	1.343	1.272	EPSD	TCGA;COSMIC	1.318	Loss
CAMK_CAMKL_QIK_SIK2_ST	Q9BV73	CEP250	Q9H0K1	SIK2	S2435	A2440T	2440	Missense	distal	5	no	1.343	1.272	EPSD	TCGA;COSMIC	1.318	Loss
STE_STE7_MEK3_MAP2K3_ST	P46734	MAP2K3	P46734	MAP2K3	S28	S28Y	28	Missense	central	0	yes	0.000	0.000	EPSD	TCGA;ICGC;COSMIC	0.000	Loss
STE_STE7_MEK3_MAP2K3_ST	P46734	MAP2K3	P46734	MAP2K3	S28	S28F	28	Missense	central	0	yes	0.000	0.000	EPSD	TCGA;ICGC;COSMIC	0.000	Loss
STE_STE7_MEK3_MAP2K3_ST	P46734	MAP2K3	P46734	MAP2K3	S46	S46P	46	Missense	central	0	yes	0.000	0.000	EPSD	TCGA;COSMIC	0.000	Loss
STE_STE7_MEK3_MAP2K3_ST	P46734	MAP2K3	P46734	MAP2K3	S212	S212N	212	Missense	central	0	yes	0.000	0.000	EPSD	TCGA;COSMIC	0.000	Loss
STE_STE7_MEK3_MAP2K3_ST	P46734	MAP2K3	P46734	MAP2K3	S218	S218Y	218	Missense	central	0	yes	0.001	0.000	PhosphoSitePlus;EPSD	TCGA;CCLE	0.000	Loss
STE_STE7_MEK3_MAP2K3_ST	P46734	MAP2K3	P46734	MAP2K3	S249	S249F	249	Missense	central	0	yes	0.000	0.000	EPSD	TCGA;COSMIC	0.000	Loss
STE_STE7_MEK3_MAP2K3_ST	Q16539	MAPK14	P46734	MAP2K3	T16	T16A	16	Missense	central	0	yes	0.000	0.000	EPSD	TCGA;ICGC	0.000	Loss
CMGC_CDK_CDK4_CDK6_ST	P06400	RB1	Q00534	CDK6	S230	F226L	226	Missense	distal	-4	no	84.487	84.516	EPSD	TCGA;ICGC;COSMIC	54.510	Up-regulation
CMGC_CDK_CDK4_CDK6_ST	P06400	RB1	Q00534	CDK6	S230	Y225C	225	Missense	distal	-5	no	84.487	84.445	EPSD	TCGA;ICGC	54.510	Down-regulation
CMGC_CDK_CDK4_CDK6_ST	P06400	RB1	Q00534	CDK6	S249	R255Q	255	Missense	distal	6	no	86.151	86.159	EPSD	TCGA;ICGC;COSMIC	54.510	Up-regulation
CMGC_CDK_CDK4_CDK6_ST	P06400	RB1	Q00534	CDK6	S249	R251Q	251	Missense	proximal	2	no	86.151	86.145	EPSD	TCGA;ICGC;COSMIC;CCLE	54.510	Down-regulation
CMGC_CDK_CDK4_CDK6_ST	P06400	RB1	Q00534	CDK6	S249	P245A	245	Missense	distal	-4	no	86.151	85.260	EPSD	TCGA;ICGC;COSMIC	54.510	Down-regulation
CMGC_CDK_CDK4_CDK6_ST	P06400	RB1	Q00534	CDK6	T252	R255Q	255	Missense	distal	3	no	83.890	83.833	EPSD	TCGA;ICGC;COSMIC	54.510	Down-regulation
CMGC_CDK_CDK4_CDK6_ST	P06400	RB1	Q00534	CDK6	T252	R251Q	251	Missense	proximal	-1	no	83.890	83.902	EPSD	TCGA;ICGC;COSMIC;CCLE	54.510	Up-regulation
CMGC_CDK_CDK4_CDK6_ST	P06400	RB1	Q00534	CDK6	T252	P245A	245	Missense	distal	-7	no	83.890	82.923	EPSD	TCGA;ICGC;COSMIC	54.510	Down-regulation
CMGC_CDK_CDK4_CDK6_ST	P06400	RB1	Q00534	CDK6	T252	R259S	259	Missense	distal	7	no	83.890	84.307	EPSD	TCGA;ICGC;COSMIC	54.510	Up-regulation
CMGC_CDK_CDK4_CDK6_ST	P06400	RB1	Q00534	CDK6	T356	S350I	350	Missense	distal	-6	no	83.463	83.636	EPSD	TCGA;ICGC;COSMIC;GDSC	54.510	Up-regulation
CMGC_CDK_CDK4_CDK6_ST	P06400	RB1	Q00534	CDK6	T373	P374A	374	Missense	proximal	1	no	83.353	2.719	EPSD	TCGA;ICGC;COSMIC	54.510	Loss
CMGC_CDK_CDK4_CDK6_ST	P06400	RB1	Q00534	CDK6	T373	M379L	379	Missense	distal	6	no	83.353	83.334	EPSD	TCGA;ICGC;COSMIC	54.510	Down-regulation
CMGC_CDK_CDK4_CDK6_ST	P06400	RB1	Q00534	CDK6	S567	S567L	567	Missense	central	0	yes	83.870	0.000	EPSD	TCGA;ICGC;COSMIC	54.510	Loss
CMGC_CDK_CDK4_CDK6_ST	P06400	RB1	Q00534	CDK6	S567	W563S	563	Missense	distal	-4	no	83.870	84.281	EPSD	TCGA;ICGC;COSMIC	54.510	Up-regulation
CMGC_CDK_CDK4_CDK6_ST	P06400	RB1	Q00534	CDK6	S567	A562E	562	Missense	distal	-5	no	83.870	83.877	EPSD	TCGA;ICGC;COSMIC	54.510	Up-regulation
CMGC_CDK_CDK4_CDK6_ST	P06400	RB1	Q00534	CDK6	S608	D604G	604	Missense	distal	-4	no	84.906	85.231	EPSD	TCGA;ICGC;COSMIC	54.510	Up-regulation
CMGC_CDK_CDK4_CDK6_ST	P06400	RB1	Q00534	CDK6	S780	I782M	782	Missense	proximal	2	no	87.105	87.109	PhosphoSitePlus;EPSD	TCGA;ICGC;COSMIC	54.510	Up-regulation
CMGC_CDK_CDK4_CDK6_ST	P06400	RB1	Q00534	CDK6	S780	R787Q	787	Missense	distal	7	no	87.105	87.139	PhosphoSitePlus;EPSD	TCGA;ICGC;COSMIC	54.510	Up-regulation
CMGC_CDK_CDK4_CDK6_ST	P06400	RB1	Q00534	CDK6	S788	I782M	782	Missense	distal	-6	no	88.702	88.707	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	54.510	Up-regulation
CMGC_CDK_CDK4_CDK6_ST	P06400	RB1	Q00534	CDK6	S788	S788N	788	Missense	central	0	yes	88.702	0.000	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	54.510	Loss
CMGC_CDK_CDK4_CDK6_ST	P06400	RB1	Q00534	CDK6	S788	R787Q	787	Missense	proximal	-1	no	88.702	88.714	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	54.510	Up-regulation
CMGC_CDK_CDK4_CDK6_ST	P06400	RB1	Q00534	CDK6	S795	S788N	788	Missense	distal	-7	no	86.408	85.800	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	54.510	Down-regulation
CMGC_CDK_CDK4_CDK6_ST	P06400	RB1	Q00534	CDK6	S795	R798W	798	Missense	distal	3	no	86.408	86.786	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC;GDSC	54.510	Up-regulation
CMGC_CDK_CDK4_CDK6_ST	P06400	RB1	Q00534	CDK6	S807	N803S	803	Missense	distal	-4	no	90.350	90.670	EPSD;PhosphoSitePlus	TCGA;ICGC	54.510	Up-regulation
CMGC_CDK_CDK4_CDK6_ST	P06400	RB1	Q00534	CDK6	T821	P827S	827	Missense	distal	6	no	86.637	86.626	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	54.510	Down-regulation
CMGC_CDK_CDK4_CDK6_ST	P06400	RB1	Q00534	CDK6	T826	P827S	827	Missense	proximal	1	no	88.837	59.198	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	54.510	Down-regulation
CMGC_CDK_CDK4_CDK6_ST	P06400	RB1	Q00534	CDK6	T841	G836C	836	Missense	distal	-5	no	57.504	57.448	EPSD	TCGA;ICGC;COSMIC	54.510	Down-regulation
CMGC_CDK_CDK4_CDK6_ST	Q08999	RBL2	Q00534	CDK6	S8	P13L	13	Missense	distal	5	no	85.035	84.579	EPSD	TCGA;ICGC;COSMIC	54.510	Down-regulation
CMGC_CDK_CDK4_CDK6_ST	Q08999	RBL2	Q00534	CDK6	S413	S420F	420	Missense	distal	7	no	86.076	85.678	EPSD	TCGA;COSMIC	54.510	Down-regulation
CMGC_CDK_CDK4_CDK6_ST	Q08999	RBL2	Q00534	CDK6	T417	S420F	420	Missense	distal	3	no	86.030	83.538	EPSD	TCGA;COSMIC	54.510	Down-regulation
CMGC_CDK_CDK4_CDK6_ST	Q08999	RBL2	Q00534	CDK6	S603	E607K	607	Missense	distal	4	no	82.154	82.101	EPSD	TCGA;COSMIC	54.510	Down-regulation
CMGC_CDK_CDK4_CDK6_ST	Q08999	RBL2	Q00534	CDK6	S603	P604S	604	Missense	proximal	1	no	82.154	52.515	EPSD	TCGA	54.510	Loss
CMGC_CDK_CDK4_CDK6_ST	Q08999	RBL2	Q00534	CDK6	S603	P604A	604	Missense	proximal	1	no	82.154	1.519	EPSD	TCGA;COSMIC	54.510	Loss
CMGC_CDK_CDK4_CDK6_ST	Q08999	RBL2	Q00534	CDK6	T661	P663A	663	Missense	proximal	2	no	54.740	54.805	EPSD	TCGA;ICGC;COSMIC	54.510	Up-regulation
CMGC_CDK_CDK4_CDK6_ST	Q08999	RBL2	Q00534	CDK6	S662	P663A	663	Missense	proximal	1	no	83.908	3.273	EPSD	TCGA;ICGC;COSMIC	54.510	Loss
CMGC_CDK_CDK4_CDK6_ST	Q08999	RBL2	Q00534	CDK6	S688	D691N	691	Missense	distal	3	no	84.753	85.301	EPSD	TCGA;ICGC;COSMIC	54.510	Up-regulation
CMGC_CDK_CDK4_CDK6_ST	Q08999	RBL2	Q00534	CDK6	T694	D691N	691	Missense	distal	-3	no	84.290	84.224	EPSD	TCGA;ICGC;COSMIC	54.510	Down-regulation
CMGC_CDK_CDK4_CDK6_ST	Q08999	RBL2	Q00534	CDK6	T694	R697L	697	Missense	distal	3	no	84.290	84.230	EPSD	TCGA;ICGC;COSMIC	54.510	Down-regulation
CMGC_CDK_CDK4_CDK6_ST	Q08999	RBL2	Q00534	CDK6	T961	V968F	968	Missense	distal	7	no	56.597	56.455	EPSD	TCGA;ICGC;COSMIC	54.510	Down-regulation
CMGC_CDK_CDK4_CDK6_ST	Q08999	RBL2	Q00534	CDK6	T961	R960G	960	Missense	proximal	-1	no	56.597	56.596	EPSD	TCGA;ICGC;COSMIC	54.510	Down-regulation
CMGC_CDK_CDK4_CDK6_ST	Q08999	RBL2	Q00534	CDK6	S965	V968F	968	Missense	distal	3	no	58.209	57.508	EPSD	TCGA;ICGC;COSMIC	54.510	Down-regulation
CMGC_CDK_CDK4_CDK6_ST	Q08999	RBL2	Q00534	CDK6	S965	R960G	960	Missense	distal	-5	no	58.209	58.221	EPSD	TCGA;ICGC;COSMIC	54.510	Up-regulation
CMGC_CDK_CDK4_CDK6_ST	Q08999	RBL2	Q00534	CDK6	S965	M969T	969	Missense	distal	4	no	58.209	58.090	EPSD	TCGA;ICGC	54.510	Down-regulation
CMGC_CDK_CDK4_CDK6_ST	Q08999	RBL2	Q00534	CDK6	S966	V968F	968	Missense	proximal	2	no	86.206	86.235	EPSD	TCGA;ICGC;COSMIC	54.510	Up-regulation
CMGC_CDK_CDK4_CDK6_ST	Q08999	RBL2	Q00534	CDK6	S966	R960G	960	Missense	distal	-6	no	86.206	86.219	EPSD	TCGA;ICGC;COSMIC	54.510	Up-regulation
CMGC_CDK_CDK4_CDK6_ST	Q08999	RBL2	Q00534	CDK6	S966	M969T	969	Missense	distal	3	no	86.206	87.156	EPSD	TCGA;ICGC	54.510	Up-regulation
CMGC_CDK_CDK4_CDK6_ST	Q08999	RBL2	Q00534	CDK6	S971	V968F	968	Missense	distal	-3	no	59.408	59.471	EPSD	TCGA;ICGC;COSMIC	54.510	Up-regulation
CMGC_CDK_CDK4_CDK6_ST	Q08999	RBL2	Q00534	CDK6	S971	M969T	969	Missense	proximal	-2	no	59.408	59.323	EPSD	TCGA;ICGC	54.510	Down-regulation
CMGC_CDK_CDK4_CDK6_ST	Q08999	RBL2	Q00534	CDK6	S972	V968F	968	Missense	distal	-4	no	54.623	54.249	EPSD	TCGA;ICGC;COSMIC	54.510	Loss
CMGC_CDK_CDK4_CDK6_ST	Q08999	RBL2	Q00534	CDK6	S972	M969T	969	Missense	distal	-3	no	54.623	54.533	EPSD	TCGA;ICGC	54.510	Down-regulation
CMGC_CDK_CDK4_CDK6_ST	Q08999	RBL2	Q00534	CDK6	S981	P987H	987	Missense	distal	6	no	56.540	56.481	EPSD	TCGA;ICGC	54.510	Down-regulation
CMGC_CDK_CDK4_CDK6_ST	Q08999	RBL2	Q00534	CDK6	T986	R989H	989	Missense	distal	3	no	82.610	82.736	EPSD	TCGA;ICGC;COSMIC	54.510	Up-regulation
CMGC_CDK_CDK4_CDK6_ST	Q08999	RBL2	Q00534	CDK6	T986	P987H	987	Missense	proximal	1	no	82.610	-10.515	EPSD	TCGA;ICGC	54.510	Loss
CMGC_CDK_CDK4_CDK6_ST	Q08999	RBL2	Q00534	CDK6	T986	G992V	992	Missense	distal	6	no	82.610	82.640	EPSD	TCGA;ICGC;COSMIC	54.510	Up-regulation
CMGC_CDK_CDK4_CDK6_ST	Q08999	RBL2	Q00534	CDK6	S1035	P1032L	1032	Missense	distal	-3	no	86.166	86.386	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	54.510	Up-regulation
CMGC_CDK_CDK4_CDK6_ST	Q08999	RBL2	Q00534	CDK6	S1035	P1033T	1033	Missense	proximal	-2	no	86.166	86.269	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	54.510	Up-regulation
CMGC_CDK_CDK4_CDK6_ST	Q08999	RBL2	Q00534	CDK6	T1042	G1043S	1043	Missense	proximal	1	no	-3.077	58.600	EPSD	TCGA	54.510	Gain
CMGC_CDK_CDK4_CDK6_ST	Q08999	RBL2	Q00534	CDK6	S1044	G1043S	1043	Missense	proximal	-1	no	84.936	85.015	EPSD	TCGA	54.510	Up-regulation
CMGC_CDK_CDK4_CDK6_ST	Q08999	RBL2	Q00534	CDK6	S1059	P1055H	1055	Missense	distal	-4	no	84.655	83.631	EPSD	TCGA	54.510	Down-regulation
CMGC_CDK_CDK4_CDK6_ST	Q08999	RBL2	Q00534	CDK6	S1068	R1070Q	1070	Missense	proximal	2	no	85.983	85.978	EPSD	TCGA;COSMIC	54.510	Down-regulation
CMGC_CDK_CDK4_CDK6_ST	Q08999	RBL2	Q00534	CDK6	S1068	K1072T	1072	Missense	distal	4	no	85.983	85.926	EPSD	TCGA;COSMIC	54.510	Down-regulation
CMGC_CDK_CDK4_CDK6_ST	Q08999	RBL2	Q00534	CDK6	S1068	K1072N	1072	Missense	distal	4	no	85.983	86.051	EPSD	TCGA	54.510	Up-regulation
CMGC_CDK_CDK4_CDK6_ST	Q08999	RBL2	Q00534	CDK6	S1080	K1083Q	1083	Missense	distal	3	no	85.244	84.010	EPSD	TCGA	54.510	Down-regulation
CMGC_CDK_CDK4_CDK6_ST	Q08999	RBL2	Q00534	CDK6	T1097	R1102T	1102	Missense	distal	5	no	85.210	85.404	EPSD	TCGA;COSMIC	54.510	Up-regulation
CMGC_CDK_CDK4_CDK6_ST	Q08999	RBL2	Q00534	CDK6	T1097	R1093C	1093	Missense	distal	-4	no	85.210	85.291	EPSD	TCGA;COSMIC	54.510	Up-regulation
CMGC_CDK_CDK4_CDK6_ST	Q08999	RBL2	Q00534	CDK6	S1112	R1116T	1116	Missense	distal	4	no	84.949	84.802	EPSD	TCGA;COSMIC	54.510	Down-regulation
CMGC_CDK_CDK4_CDK6_ST	Q08999	RBL2	Q00534	CDK6	S1112	S1110N	1110	Missense	proximal	-2	no	84.949	85.091	EPSD	TCGA;COSMIC	54.510	Up-regulation
CMGC_CDK_CDK4_CDK6_ST	Q08999	RBL2	Q00534	CDK6	S1112	L1105I	1105	Missense	distal	-7	no	84.949	85.211	EPSD	TCGA;COSMIC	54.510	Up-regulation
CMGC_CDK_CDK4_CDK6_ST	Q08050	FOXM1	Q00534	CDK6	S4	I10V	10	Missense	distal	6	no	83.217	83.228	EPSD	TCGA;ICGC;COSMIC	54.510	Up-regulation
CMGC_CDK_CDK4_CDK6_ST	Q08050	FOXM1	Q00534	CDK6	T27	A23T	23	Missense	distal	-4	no	54.371	54.844	EPSD	TCGA;ICGC;COSMIC	54.510	Gain
CMGC_CDK_CDK4_CDK6_ST	Q08050	FOXM1	Q00534	CDK6	S191	R198H	198	Missense	distal	7	no	54.784	54.796	EPSD	TCGA;ICGC;COSMIC	54.510	Up-regulation
CMGC_CDK_CDK4_CDK6_ST	Q08050	FOXM1	Q00534	CDK6	S581	L588I	588	Missense	distal	7	no	58.120	58.237	EPSD	TCGA;ICGC	54.510	Up-regulation
CMGC_CDK_CDK4_CDK6_ST	Q08050	FOXM1	Q00534	CDK6	S704	S704N	704	Missense	central	0	yes	87.020	0.000	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	54.510	Loss
CMGC_CDK_CDK4_CDK6_ST	P38936	CDKN1A	Q00534	CDK6	T57	G61V	61	Missense	distal	4	no	84.771	84.686	EPSD	TCGA;ICGC;COSMIC	54.510	Down-regulation
CMGC_CDK_CDK4_CDK6_ST	P38936	CDKN1A	Q00534	CDK6	T57	E56K	56	Missense	proximal	-1	no	84.771	84.784	EPSD	TCGA;ICGC;COSMIC	54.510	Up-regulation
CMGC_CDK_CDK4_CDK6_ST	P38936	CDKN1A	Q00534	CDK6	T57	P58L	58	Missense	proximal	1	no	84.771	-12.236	EPSD	TCGA;ICGC;COSMIC	54.510	Loss
CMGC_CDK_CDK4_CDK6_ST	P38936	CDKN1A	Q00534	CDK6	S98	R94W	94	Missense	distal	-4	no	84.272	84.335	EPSD	TCGA;ICGC;COSMIC	54.510	Up-regulation
CMGC_CDK_CDK4_CDK6_ST	P38936	CDKN1A	Q00534	CDK6	S98	R93S	93	Missense	distal	-5	no	84.272	84.084	EPSD	TCGA;ICGC;COSMIC	54.510	Down-regulation
CMGC_CDK_CDK4_CDK6_ST	P38936	CDKN1A	Q00534	CDK6	S98	R94P	94	Missense	distal	-4	no	84.272	85.323	EPSD	TCGA;ICGC;COSMIC	54.510	Up-regulation
CMGC_CDK_CDK4_CDK6_ST	P38936	CDKN1A	Q00534	CDK6	S98	P95S	95	Missense	distal	-3	no	84.272	84.340	EPSD	TCGA;ICGC;COSMIC	54.510	Up-regulation
CMGC_CDK_CDK4_CDK6_ST	P38936	CDKN1A	Q00534	CDK6	S130	D136H	136	Missense	distal	6	no	85.601	85.625	PhosphoSitePlus	TCGA;ICGC;COSMIC	54.510	Up-regulation
CMGC_CDK_CDK4_CDK6_ST	P38936	CDKN1A	Q00534	CDK6	S130	G132C	132	Missense	proximal	2	no	85.601	85.576	PhosphoSitePlus	TCGA;ICGC;COSMIC	54.510	Down-regulation
CMGC_CDK_CDK4_CDK6_ST	P38936	CDKN1A	Q00534	CDK6	S130	E128K	128	Missense	proximal	-2	no	85.601	85.582	PhosphoSitePlus	TCGA;ICGC;COSMIC	54.510	Down-regulation
CMGC_CDK_CDK4_CDK6_ST	P38936	CDKN1A	Q00534	CDK6	S130	G135A	135	Missense	distal	5	no	85.601	85.663	PhosphoSitePlus	TCGA	54.510	Up-regulation
CMGC_CDK_CDK4_CDK6_ST	P38936	CDKN1A	Q00534	CDK6	T145	D149H	149	Missense	distal	4	no	54.973	54.927	EPSD	TCGA;ICGC;COSMIC	54.510	Down-regulation
CMGC_CDK_CDK4_CDK6_ST	P38936	CDKN1A	Q00534	CDK6	T145	R142W	142	Missense	distal	-3	no	54.973	54.965	EPSD	TCGA;ICGC;COSMIC;GDSC;CCLE	54.510	Down-regulation
CMGC_CDK_CDK4_CDK6_ST	Q01196	RUNX1	Q00534	CDK6	S212	P216H	216	Missense	distal	4	no	83.867	84.094	EPSD	TCGA	54.510	Up-regulation
CMGC_CDK_CDK4_CDK6_ST	Q01196	RUNX1	Q00534	CDK6	T219	P216H	216	Missense	distal	-3	no	87.946	88.167	EPSD	TCGA	54.510	Up-regulation
CMGC_CDK_CDK4_CDK6_ST	Q01196	RUNX1	Q00534	CDK6	S435	A440T	440	Missense	distal	5	no	84.350	84.479	EPSD	TCGA;ICGC;COSMIC	54.510	Up-regulation
CMGC_CDK_CDK4_CDK6_ST	Q96KS0	EGLN2	Q00534	CDK6	S74	R77Q	77	Missense	distal	3	no	84.198	84.141	EPSD	TCGA;ICGC;COSMIC	54.510	Down-regulation
CMGC_CDK_CDK4_CDK6_ST	Q96KS0	EGLN2	Q00534	CDK6	S74	R77W	77	Missense	distal	3	no	84.198	84.576	EPSD	TCGA;ICGC;COSMIC	54.510	Up-regulation
CMGC_CDK_CDK4_CDK6_ST	Q96KS0	EGLN2	Q00534	CDK6	S74	A68T	68	Missense	distal	-6	no	84.198	84.138	EPSD	TCGA;ICGC	54.510	Down-regulation
CMGC_CDK_CDK4_CDK6_ST	Q96KS0	EGLN2	Q00534	CDK6	S130	R134Q	134	Missense	distal	4	no	85.564	85.563	PhosphoSitePlus	TCGA;ICGC;COSMIC	54.510	Down-regulation
CMGC_CDK_CDK4_CDK6_ST	Q96KS0	EGLN2	Q00534	CDK6	S130	R134L	134	Missense	distal	4	no	85.564	85.572	PhosphoSitePlus	TCGA;ICGC	54.510	Up-regulation
CMGC_CDK_CDK4_CDK6_ST	Q96KS0	EGLN2	Q00534	CDK6	S155	A161T	161	Missense	distal	6	no	57.175	57.224	EPSD	TCGA;ICGC;COSMIC	54.510	Up-regulation
CMGC_CDK_CDK4_CDK6_ST	Q96KS0	EGLN2	Q00534	CDK6	T405	V400A	400	Missense	distal	-5	no	82.582	82.630	EPSD	TCGA;COSMIC	54.510	Up-regulation
CMGC_CDK_CDK4_CDK6_ST	P14618	PKM	Q00534	CDK6	S37	R43P	43	Missense	distal	6	no	85.695	85.760	PhosphoSitePlus	TCGA;ICGC;COSMIC	54.510	Up-regulation
CMGC_CDK_CDK4_CDK6_ST	P14618	PKM	Q00534	CDK6	S37	R32C	32	Missense	distal	-5	no	85.695	85.651	PhosphoSitePlus	TCGA;ICGC;COSMIC	54.510	Down-regulation
CMGC_CDK_CDK4_CDK6_ST	P14618	PKM	Q00534	CDK6	S37	R32H	32	Missense	distal	-5	no	85.695	85.678	PhosphoSitePlus	TCGA;ICGC;COSMIC	54.510	Down-regulation
CMGC_CDK_CDK4_CDK6_ST	P14618	PKM	Q00534	CDK6	S127	G128S	128	Missense	proximal	1	no	-5.866	55.810	EPSD	TCGA;ICGC;COSMIC	54.510	Gain
CMGC_CDK_CDK4_CDK6_ST	P14618	PKM	Q00534	CDK6	T143	L144P	144	Missense	proximal	1	no	-13.618	83.390	EPSD	TCGA;ICGC;COSMIC	54.510	Gain
CMGC_CDK_CDK4_CDK6_ST	P14618	PKM	Q00534	CDK6	T405	R400Q	400	Missense	distal	-5	no	56.058	56.012	EPSD	TCGA	54.510	Down-regulation
CMGC_CDK_CDK4_CDK6_ST	P21333	FLNA	Q00534	CDK6	S3	A8V	8	Missense	distal	5	no	55.674	55.730	EPSD	TCGA;ICGC;COSMIC	54.510	Up-regulation
CMGC_CDK_CDK4_CDK6_ST	P21333	FLNA	Q00534	CDK6	S368	F370Y	370	Missense	proximal	2	no	83.507	83.511	EPSD	TCGA;ICGC;COSMIC	54.510	Up-regulation
CMGC_CDK_CDK4_CDK6_ST	P21333	FLNA	Q00534	CDK6	S368	E371D	371	Missense	distal	3	no	83.507	82.740	EPSD	TCGA;ICGC	54.510	Down-regulation
CMGC_CDK_CDK4_CDK6_ST	P21333	FLNA	Q00534	CDK6	S368	E371K	371	Missense	distal	3	no	83.507	84.311	EPSD	TCGA;ICGC	54.510	Up-regulation
CMGC_CDK_CDK4_CDK6_ST	P21333	FLNA	Q00534	CDK6	S368	A366T	366	Missense	proximal	-2	no	83.507	83.421	EPSD	TCGA;ICGC;COSMIC;CCLE	54.510	Down-regulation
CMGC_CDK_CDK4_CDK6_ST	P21333	FLNA	Q00534	CDK6	S368	V372A	372	Missense	distal	4	no	83.507	83.540	EPSD	TCGA;ICGC	54.510	Up-regulation
CMGC_CDK_CDK4_CDK6_ST	P21333	FLNA	Q00534	CDK6	S468	P466L	466	Missense	proximal	-2	no	84.390	84.631	EPSD	TCGA;ICGC;COSMIC	54.510	Up-regulation
CMGC_CDK_CDK4_CDK6_ST	P21333	FLNA	Q00534	CDK6	S468	R467C	467	Missense	proximal	-1	no	84.390	84.405	EPSD	TCGA;ICGC;COSMIC	54.510	Up-regulation
CMGC_CDK_CDK4_CDK6_ST	P21333	FLNA	Q00534	CDK6	S468	P464S	464	Missense	distal	-4	no	84.390	83.812	EPSD	TCGA;ICGC	54.510	Down-regulation
CMGC_CDK_CDK4_CDK6_ST	P21333	FLNA	Q00534	CDK6	S468	V472A	472	Missense	distal	4	no	84.390	84.423	EPSD	TCGA;ICGC	54.510	Up-regulation
CMGC_CDK_CDK4_CDK6_ST	P21333	FLNA	Q00534	CDK6	S468	R467H	467	Missense	proximal	-1	no	84.390	84.396	EPSD	TCGA;ICGC	54.510	Up-regulation
CMGC_CDK_CDK4_CDK6_ST	P21333	FLNA	Q00534	CDK6	S564	E567K	567	Missense	distal	3	no	84.560	85.364	EPSD	TCGA;ICGC;COSMIC	54.510	Up-regulation
CMGC_CDK_CDK4_CDK6_ST	P21333	FLNA	Q00534	CDK6	S564	G562W	562	Missense	proximal	-2	no	84.560	84.523	EPSD	TCGA;ICGC;COSMIC	54.510	Down-regulation
CMGC_CDK_CDK4_CDK6_ST	P21333	FLNA	Q00534	CDK6	S564	Q559E	559	Missense	distal	-5	no	84.560	84.549	EPSD	TCGA;ICGC;COSMIC	54.510	Down-regulation
CMGC_CDK_CDK4_CDK6_ST	P21333	FLNA	Q00534	CDK6	S564	P565L	565	Missense	proximal	1	no	84.560	-12.447	EPSD	TCGA;ICGC;COSMIC	54.510	Loss
CMGC_CDK_CDK4_CDK6_ST	P21333	FLNA	Q00534	CDK6	S657	R655H	655	Missense	proximal	-2	no	81.950	81.954	EPSD	TCGA;ICGC;COSMIC	54.510	Up-regulation
CMGC_CDK_CDK4_CDK6_ST	P21333	FLNA	Q00534	CDK6	S657	L656I	656	Missense	proximal	-1	no	81.950	81.973	EPSD	TCGA;ICGC	54.510	Up-regulation
CMGC_CDK_CDK4_CDK6_ST	P21333	FLNA	Q00534	CDK6	S657	R664L	664	Missense	distal	7	no	81.950	81.910	EPSD	TCGA;ICGC;COSMIC	54.510	Down-regulation
CMGC_CDK_CDK4_CDK6_ST	P21333	FLNA	Q00534	CDK6	S757	G751D	751	Missense	distal	-6	no	84.185	84.206	EPSD	TCGA;ICGC;COSMIC	54.510	Up-regulation
CMGC_CDK_CDK4_CDK6_ST	P21333	FLNA	Q00534	CDK6	S757	N756K	756	Missense	proximal	-1	no	84.185	84.202	EPSD	TCGA;ICGC;COSMIC	54.510	Up-regulation
CMGC_CDK_CDK4_CDK6_ST	P21333	FLNA	Q00534	CDK6	S757	S757N	757	Missense	central	0	yes	84.185	0.000	EPSD	TCGA;ICGC	54.510	Loss
CMGC_CDK_CDK4_CDK6_ST	P21333	FLNA	Q00534	CDK6	S757	S753G	753	Missense	distal	-4	no	84.185	83.832	EPSD	TCGA;ICGC;COSMIC	54.510	Down-regulation
CMGC_CDK_CDK4_CDK6_ST	P21333	FLNA	Q00534	CDK6	S757	N756D	756	Missense	proximal	-1	no	84.185	84.157	EPSD	TCGA;ICGC	54.510	Down-regulation
CMGC_CDK_CDK4_CDK6_ST	P21333	FLNA	Q00534	CDK6	S757	G750E	750	Missense	distal	-7	no	84.185	84.534	EPSD	TCGA;ICGC	54.510	Up-regulation
CMGC_CDK_CDK4_CDK6_ST	P21333	FLNA	Q00534	CDK6	S757	S753T	753	Missense	distal	-4	no	84.185	84.346	EPSD	TCGA	54.510	Up-regulation
CMGC_CDK_CDK4_CDK6_ST	P21333	FLNA	Q00534	CDK6	T847	I848S	848	Missense	proximal	1	no	8.090	56.919	EPSD	TCGA;ICGC;COSMIC	54.510	Gain
CMGC_CDK_CDK4_CDK6_ST	P21333	FLNA	Q00534	CDK6	T857	T857M	857	Missense	central	0	yes	87.210	0.000	EPSD	TCGA;COSMIC	54.510	Loss
CMGC_CDK_CDK4_CDK6_ST	P21333	FLNA	Q00534	CDK6	S860	T857M	857	Missense	distal	-3	no	83.018	83.109	EPSD	TCGA;COSMIC	54.510	Up-regulation
CMGC_CDK_CDK4_CDK6_ST	P21333	FLNA	Q00534	CDK6	S959	D954Y	954	Missense	distal	-5	no	86.374	86.324	EPSD	TCGA;ICGC;COSMIC	54.510	Down-regulation
CMGC_CDK_CDK4_CDK6_ST	P21333	FLNA	Q00534	CDK6	S959	F961L	961	Missense	proximal	2	no	86.374	86.382	EPSD	TCGA;ICGC	54.510	Up-regulation
CMGC_CDK_CDK4_CDK6_ST	P21333	FLNA	Q00534	CDK6	S966	P967S	967	Missense	proximal	1	no	84.931	55.292	EPSD	TCGA;ICGC;COSMIC	54.510	Down-regulation
CMGC_CDK_CDK4_CDK6_ST	P21333	FLNA	Q00534	CDK6	S966	F961L	961	Missense	distal	-5	no	84.931	84.961	EPSD	TCGA;ICGC	54.510	Up-regulation
CMGC_CDK_CDK4_CDK6_ST	P21333	FLNA	Q00534	CDK6	S1055	P1051H	1051	Missense	distal	-4	no	86.895	85.871	EPSD	TCGA;ICGC;COSMIC	54.510	Down-regulation
CMGC_CDK_CDK4_CDK6_ST	P21333	FLNA	Q00534	CDK6	S1055	P1053H	1053	Missense	proximal	-2	no	86.895	87.122	EPSD	TCGA;ICGC	54.510	Up-regulation
CMGC_CDK_CDK4_CDK6_ST	P21333	FLNA	Q00534	CDK6	S1084	A1082V	1082	Missense	proximal	-2	no	83.347	83.317	EPSD	TCGA;ICGC	54.510	Down-regulation
CMGC_CDK_CDK4_CDK6_ST	P21333	FLNA	Q00534	CDK6	S1084	R1087H	1087	Missense	distal	3	no	83.347	83.473	EPSD	TCGA;ICGC;COSMIC	54.510	Up-regulation
CMGC_CDK_CDK4_CDK6_ST	P21333	FLNA	Q00534	CDK6	S1084	R1087L	1087	Missense	distal	3	no	83.347	83.287	EPSD	TCGA;ICGC;COSMIC	54.510	Down-regulation
CMGC_CDK_CDK4_CDK6_ST	P21333	FLNA	Q00534	CDK6	S1084	P1085S	1085	Missense	proximal	1	no	83.347	53.708	EPSD	TCGA;ICGC;COSMIC	54.510	Loss
CMGC_CDK_CDK4_CDK6_ST	P21333	FLNA	Q00534	CDK6	S1084	D1091N	1091	Missense	distal	7	no	83.347	83.457	EPSD	TCGA;ICGC	54.510	Up-regulation
CMGC_CDK_CDK4_CDK6_ST	P21333	FLNA	Q00534	CDK6	S1084	L1077P	1077	Missense	distal	-7	no	83.347	84.492	EPSD	TCGA;ICGC;COSMIC	54.510	Up-regulation
CMGC_CDK_CDK4_CDK6_ST	P21333	FLNA	Q00534	CDK6	T1255	Y1261H	1261	Missense	distal	6	no	55.305	55.311	EPSD	TCGA;ICGC	54.510	Up-regulation
CMGC_CDK_CDK4_CDK6_ST	P21333	FLNA	Q00534	CDK6	T1322	G1315D	1315	Missense	distal	-7	no	84.151	84.017	EPSD	TCGA;ICGC	54.510	Down-regulation
CMGC_CDK_CDK4_CDK6_ST	P21333	FLNA	Q00534	CDK6	S1338	G1337V	1337	Missense	proximal	-1	no	85.792	85.828	EPSD	TCGA;ICGC;COSMIC	54.510	Up-regulation
CMGC_CDK_CDK4_CDK6_ST	P21333	FLNA	Q00534	CDK6	S1338	F1345V	1345	Missense	distal	7	no	85.792	85.935	EPSD	TCGA;ICGC	54.510	Up-regulation
CMGC_CDK_CDK4_CDK6_ST	P21333	FLNA	Q00534	CDK6	S1343	G1337V	1337	Missense	distal	-6	no	84.864	84.776	EPSD	TCGA;ICGC;COSMIC	54.510	Down-regulation
CMGC_CDK_CDK4_CDK6_ST	P21333	FLNA	Q00534	CDK6	S1343	Q1346H	1346	Missense	distal	3	no	84.864	85.047	EPSD	TCGA;ICGC;COSMIC	54.510	Up-regulation
CMGC_CDK_CDK4_CDK6_ST	P21333	FLNA	Q00534	CDK6	S1343	F1345V	1345	Missense	proximal	2	no	84.864	84.835	EPSD	TCGA;ICGC	54.510	Down-regulation
CMGC_CDK_CDK4_CDK6_ST	P21333	FLNA	Q00534	CDK6	S1436	F1438L	1438	Missense	proximal	2	no	85.444	85.452	EPSD	TCGA;ICGC;COSMIC	54.510	Up-regulation
CMGC_CDK_CDK4_CDK6_ST	P21333	FLNA	Q00534	CDK6	S1459	P1456T	1456	Missense	distal	-3	no	84.005	84.090	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	54.510	Up-regulation
CMGC_CDK_CDK4_CDK6_ST	P21333	FLNA	Q00534	CDK6	S1459	P1456L	1456	Missense	distal	-3	no	84.005	84.225	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	54.510	Up-regulation
CMGC_CDK_CDK4_CDK6_ST	P21333	FLNA	Q00534	CDK6	S1459	V1463L	1463	Missense	distal	4	no	84.005	84.074	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	54.510	Up-regulation
CMGC_CDK_CDK4_CDK6_ST	P21333	FLNA	Q00534	CDK6	S1459	S1459N	1459	Missense	central	0	yes	84.005	0.000	EPSD;PhosphoSitePlus	TCGA;ICGC	54.510	Loss
CMGC_CDK_CDK4_CDK6_ST	P21333	FLNA	Q00534	CDK6	T1475	F1471I	1471	Missense	distal	-4	no	54.962	55.116	EPSD	TCGA;ICGC;COSMIC	54.510	Up-regulation
CMGC_CDK_CDK4_CDK6_ST	P21333	FLNA	Q00534	CDK6	T1475	V1480M	1480	Missense	distal	5	no	54.962	54.890	EPSD	TCGA;ICGC;COSMIC	54.510	Down-regulation
CMGC_CDK_CDK4_CDK6_ST	P21333	FLNA	Q00534	CDK6	S1533	D1527E	1527	Missense	distal	-6	no	85.451	85.366	EPSD	TCGA;ICGC;COSMIC	54.510	Down-regulation
CMGC_CDK_CDK4_CDK6_ST	P21333	FLNA	Q00534	CDK6	S1533	R1532L	1532	Missense	proximal	-1	no	85.451	85.446	EPSD	TCGA;ICGC;COSMIC	54.510	Down-regulation
CMGC_CDK_CDK4_CDK6_ST	P21333	FLNA	Q00534	CDK6	S1630	R1635C	1635	Missense	distal	5	no	83.760	83.773	EPSD	TCGA;ICGC;COSMIC	54.510	Up-regulation
CMGC_CDK_CDK4_CDK6_ST	P21333	FLNA	Q00534	CDK6	S1630	P1628L	1628	Missense	proximal	-2	no	83.760	84.001	EPSD	TCGA;ICGC;COSMIC	54.510	Up-regulation
CMGC_CDK_CDK4_CDK6_ST	P21333	FLNA	Q00534	CDK6	S1630	P1631S	1631	Missense	proximal	1	no	83.760	54.121	EPSD	TCGA;ICGC;COSMIC	54.510	Loss
CMGC_CDK_CDK4_CDK6_ST	P21333	FLNA	Q00534	CDK6	S1630	V1637M	1637	Missense	distal	7	no	83.760	83.669	EPSD	TCGA;ICGC;COSMIC;CCLE	54.510	Down-regulation
CMGC_CDK_CDK4_CDK6_ST	P21333	FLNA	Q00534	CDK6	S1630	R1633H	1633	Missense	distal	3	no	83.760	83.886	EPSD	TCGA;ICGC;COSMIC;GDSC;CCLE	54.510	Up-regulation
CMGC_CDK_CDK4_CDK6_ST	P21333	FLNA	Q00534	CDK6	S1734	N1733S	1733	Missense	proximal	-1	no	84.001	84.064	EPSD	TCGA;COSMIC	54.510	Up-regulation
CMGC_CDK_CDK4_CDK6_ST	P21333	FLNA	Q00534	CDK6	S1854	D1847G	1847	Missense	distal	-7	no	82.296	82.430	EPSD	TCGA;COSMIC	54.510	Up-regulation
CMGC_CDK_CDK4_CDK6_ST	P21333	FLNA	Q00534	CDK6	S2032	V2030M	2030	Missense	proximal	-2	no	54.592	54.619	EPSD	TCGA;COSMIC	54.510	Up-regulation
CMGC_CDK_CDK4_CDK6_ST	P21333	FLNA	Q00534	CDK6	S2032	P2036L	2036	Missense	distal	4	no	54.592	54.817	EPSD	TCGA;COSMIC	54.510	Up-regulation
CMGC_CDK_CDK4_CDK6_ST	P21333	FLNA	Q00534	CDK6	S2033	V2030M	2030	Missense	distal	-3	no	85.700	85.727	EPSD	TCGA;COSMIC	54.510	Up-regulation
CMGC_CDK_CDK4_CDK6_ST	P21333	FLNA	Q00534	CDK6	S2033	P2036L	2036	Missense	distal	3	no	85.700	83.525	EPSD	TCGA;COSMIC	54.510	Down-regulation
CMGC_CDK_CDK4_CDK6_ST	P21333	FLNA	Q00534	CDK6	S2128	S2131Y	2131	Missense	distal	3	no	86.695	84.354	EPSD	TCGA;COSMIC	54.510	Down-regulation
CMGC_CDK_CDK4_CDK6_ST	P21333	FLNA	Q00534	CDK6	S2128	G2127D	2127	Missense	proximal	-1	no	86.695	86.682	EPSD	TCGA;COSMIC	54.510	Down-regulation
CMGC_CDK_CDK4_CDK6_ST	P21333	FLNA	Q00534	CDK6	T2179	Q2177H	2177	Missense	proximal	-2	no	56.659	56.683	EPSD	TCGA;COSMIC	54.510	Up-regulation
CMGC_CDK_CDK4_CDK6_ST	P21333	FLNA	Q00534	CDK6	S2180	Q2177H	2177	Missense	distal	-3	no	83.045	83.067	EPSD	TCGA;COSMIC	54.510	Up-regulation
CMGC_CDK_CDK4_CDK6_ST	P21333	FLNA	Q00534	CDK6	S2224	V2230L	2230	Missense	distal	6	no	83.999	83.967	EPSD	TCGA;COSMIC	54.510	Down-regulation
CMGC_CDK_CDK4_CDK6_ST	P21333	FLNA	Q00534	CDK6	S2224	V2230M	2230	Missense	distal	6	no	83.999	83.986	EPSD	TCGA;COSMIC;GDSC;CCLE	54.510	Down-regulation
CMGC_CDK_CDK4_CDK6_ST	P21333	FLNA	Q00534	CDK6	S2319	V2322M	2322	Missense	distal	3	no	85.345	84.959	EPSD	TCGA;COSMIC	54.510	Down-regulation
CMGC_CDK_CDK4_CDK6_ST	P21333	FLNA	Q00534	CDK6	S2319	P2324H	2324	Missense	distal	5	no	85.345	84.922	EPSD	TCGA;COSMIC	54.510	Down-regulation
CMGC_CDK_CDK4_CDK6_ST	P21333	FLNA	Q00534	CDK6	S2327	P2328T	2328	Missense	proximal	1	no	84.700	16.092	EPSD	TCGA;ICGC;COSMIC	54.510	Loss
CMGC_CDK_CDK4_CDK6_ST	P21333	FLNA	Q00534	CDK6	S2327	P2328L	2328	Missense	proximal	1	no	84.700	-12.307	EPSD	TCGA;COSMIC	54.510	Loss
CMGC_CDK_CDK4_CDK6_ST	P21333	FLNA	Q00534	CDK6	S2327	V2322M	2322	Missense	distal	-5	no	84.700	84.748	EPSD	TCGA;COSMIC	54.510	Up-regulation
CMGC_CDK_CDK4_CDK6_ST	P21333	FLNA	Q00534	CDK6	S2327	R2334H	2334	Missense	distal	7	no	84.700	84.711	EPSD	TCGA;COSMIC;GDSC;CCLE	54.510	Up-regulation
CMGC_CDK_CDK4_CDK6_ST	P21333	FLNA	Q00534	CDK6	S2327	P2324H	2324	Missense	distal	-3	no	84.700	84.920	EPSD	TCGA;COSMIC	54.510	Up-regulation
CMGC_CDK_CDK4_CDK6_ST	P21333	FLNA	Q00534	CDK6	S2327	A2332T	2332	Missense	distal	5	no	84.700	84.829	EPSD	TCGA;COSMIC	54.510	Up-regulation
CMGC_CDK_CDK4_CDK6_ST	P21333	FLNA	Q00534	CDK6	S2338	R2334H	2334	Missense	distal	-4	no	56.455	56.482	EPSD	TCGA;COSMIC;GDSC;CCLE	54.510	Up-regulation
CMGC_CDK_CDK4_CDK6_ST	P21333	FLNA	Q00534	CDK6	S2338	E2342K	2342	Missense	distal	4	no	56.455	56.402	EPSD	TCGA	54.510	Down-regulation
CMGC_CDK_CDK4_CDK6_ST	P21333	FLNA	Q00534	CDK6	S2338	A2332T	2332	Missense	distal	-6	no	56.455	56.396	EPSD	TCGA;COSMIC	54.510	Down-regulation
CMGC_CDK_CDK4_CDK6_ST	P21333	FLNA	Q00534	CDK6	S2370	S2372L	2372	Missense	proximal	2	no	81.913	81.997	EPSD	TCGA;COSMIC	54.510	Up-regulation
CMGC_CDK_CDK4_CDK6_ST	P21333	FLNA	Q00534	CDK6	S2370	H2369Y	2369	Missense	proximal	-1	no	81.913	81.914	EPSD	TCGA;COSMIC	54.510	Up-regulation
CMGC_CDK_CDK4_CDK6_ST	P21333	FLNA	Q00534	CDK6	S2370	A2363V	2363	Missense	distal	-7	no	81.913	82.028	EPSD	TCGA;COSMIC	54.510	Up-regulation
CMGC_CDK_CDK4_CDK6_ST	P21333	FLNA	Q00534	CDK6	S2370	P2371L	2371	Missense	proximal	1	no	81.913	-15.094	EPSD	TCGA;COSMIC	54.510	Loss
CMGC_CDK_CDK4_CDK6_ST	P21333	FLNA	Q00534	CDK6	S2370	A2374S	2374	Missense	distal	4	no	81.913	81.809	EPSD	TCGA;COSMIC	54.510	Down-regulation
CMGC_CDK_CDK4_CDK6_ST	P21333	FLNA	Q00534	CDK6	S2414	P2415S	2415	Missense	proximal	1	no	83.173	53.535	EPSD	TCGA	54.510	Loss
CMGC_CDK_CDK4_CDK6_ST	P21333	FLNA	Q00534	CDK6	T2488	A2491S	2491	Missense	distal	3	no	84.315	86.364	EPSD	TCGA;COSMIC	54.510	Up-regulation
CMGC_CDK_CDK4_CDK6_ST	P21333	FLNA	Q00534	CDK6	T2488	V2485A	2485	Missense	distal	-3	no	84.315	84.340	EPSD	TCGA;COSMIC	54.510	Up-regulation
CMGC_CDK_CDK4_CDK6_ST	P21333	FLNA	Q00534	CDK6	T2488	R2484H	2484	Missense	distal	-4	no	84.315	84.342	EPSD	TCGA	54.510	Up-regulation
CMGC_CDK_CDK4_CDK6_ST	P21333	FLNA	Q00534	CDK6	S2510	F2512L	2512	Missense	proximal	2	no	86.373	86.380	EPSD	TCGA;COSMIC	54.510	Up-regulation
CMGC_CDK_CDK4_CDK6_ST	P21333	FLNA	Q00534	CDK6	S2510	A2514V	2514	Missense	distal	4	no	86.373	86.340	EPSD	TCGA	54.510	Down-regulation
CMGC_CDK_CDK4_CDK6_ST	P21333	FLNA	Q00534	CDK6	T2530	V2535A	2535	Missense	distal	5	no	56.717	56.661	EPSD	TCGA;ICGC;COSMIC	54.510	Down-regulation
CMGC_CDK_CDK4_CDK6_ST	P21333	FLNA	Q00534	CDK6	T2530	S2526I	2526	Missense	distal	-4	no	56.717	56.352	EPSD	TCGA	54.510	Down-regulation
CMGC_CDK_CDK4_CDK6_ST	P21333	FLNA	Q00534	CDK6	T2530	S2537F	2537	Missense	distal	7	no	56.717	56.319	EPSD	TCGA;COSMIC	54.510	Down-regulation
CMGC_CDK_CDK4_CDK6_ST	P21333	FLNA	Q00534	CDK6	T2530	S2523T	2523	Missense	distal	-7	no	56.717	56.720	EPSD	TCGA;COSMIC	54.510	Up-regulation
CMGC_CDK_CDK4_CDK6_ST	P21333	FLNA	Q00534	CDK6	T2599	P2600L	2600	Missense	proximal	1	no	83.572	-13.436	EPSD	TCGA;COSMIC	54.510	Loss
CMGC_CDK_CDK4_CDK6_ST	P21333	FLNA	Q00534	CDK6	T2599	E2602D	2602	Missense	distal	3	no	83.572	82.805	EPSD	TCGA;COSMIC	54.510	Down-regulation
CMGC_CDK_CDK4_CDK6_ST	P21333	FLNA	Q00534	CDK6	T2599	E2603K	2603	Missense	distal	4	no	83.572	83.519	EPSD	TCGA;COSMIC	54.510	Down-regulation
CMGC_CDK_CDK4_CDK6_ST	P21333	FLNA	Q00534	CDK6	S2640	D2634N	2634	Missense	distal	-6	no	82.692	82.629	EPSD	TCGA;COSMIC	54.510	Down-regulation
CMGC_CDK_CDK4_CDK6_ST	P21333	FLNA	Q00534	CDK6	S2640	R2643H	2643	Missense	distal	3	no	82.692	82.818	EPSD	TCGA;COSMIC	54.510	Up-regulation
CMGC_CDK_CDK4_CDK6_ST	P21333	FLNA	Q00534	CDK6	S2640	E2635K	2635	Missense	distal	-5	no	82.692	82.658	EPSD	TCGA;COSMIC	54.510	Down-regulation
CMGC_CDK_CDK4_CDK6_ST	P21333	FLNA	Q00534	CDK6	S2640	I2637N	2637	Missense	distal	-3	no	82.692	82.700	EPSD	TCGA;COSMIC	54.510	Up-regulation
CMGC_CDK_CDK4_CDK6_ST	P46527	CDKN1B	Q00534	CDK6	S10	S7C	7	Missense	distal	-3	no	83.673	83.802	PhosphoSitePlus;EPSD	TCGA;ICGC;COSMIC	54.510	Up-regulation
CMGC_CDK_CDK4_CDK6_ST	P46527	CDKN1B	Q00534	CDK6	S10	G9W	9	Missense	proximal	-1	no	83.673	83.688	PhosphoSitePlus;EPSD	TCGA;ICGC;COSMIC	54.510	Up-regulation
CMGC_CDK_CDK4_CDK6_ST	Q16875	PFKFB3	Q00534	CDK6	S172	D177N	177	Missense	distal	5	no	84.985	85.104	EPSD	TCGA;ICGC;COSMIC	54.510	Up-regulation
CMGC_CDK_CDK4_CDK6_ST	Q16875	PFKFB3	Q00534	CDK6	T463	S461C	461	Missense	proximal	-2	no	84.581	84.731	EPSD;PhosphoSitePlus	TCGA;COSMIC	54.510	Up-regulation
CMGC_CDK_CDK4_CDK6_ST	Q16875	PFKFB3	Q00534	CDK6	T463	P464L	464	Missense	proximal	1	no	84.581	-12.426	EPSD;PhosphoSitePlus	TCGA;COSMIC	54.510	Loss
CMGC_CDK_CDK4_CDK6_ST	Q16875	PFKFB3	Q00534	CDK6	T463	N460Y	460	Missense	distal	-3	no	84.581	84.607	EPSD;PhosphoSitePlus	TCGA;COSMIC	54.510	Up-regulation
CMGC_CDK_CDK4_CDK6_ST	Q16875	PFKFB3	Q00534	CDK6	T463	E469K	469	Missense	distal	6	no	84.581	84.598	EPSD;PhosphoSitePlus	TCGA;COSMIC	54.510	Up-regulation
CMGC_CDK_CDK4_CDK6_ST	Q16875	PFKFB3	Q00534	CDK6	S467	S461C	461	Missense	distal	-6	no	86.405	86.594	PhosphoSitePlus;EPSD	TCGA;COSMIC	54.510	Up-regulation
CMGC_CDK_CDK4_CDK6_ST	Q16875	PFKFB3	Q00534	CDK6	S467	P464L	464	Missense	distal	-3	no	86.405	86.626	PhosphoSitePlus;EPSD	TCGA;COSMIC	54.510	Up-regulation
CMGC_CDK_CDK4_CDK6_ST	Q16875	PFKFB3	Q00534	CDK6	S467	N460Y	460	Missense	distal	-7	no	86.405	86.264	PhosphoSitePlus;EPSD	TCGA;COSMIC	54.510	Down-regulation
CMGC_CDK_CDK4_CDK6_ST	Q16875	PFKFB3	Q00534	CDK6	S467	E469K	469	Missense	proximal	2	no	86.405	86.391	PhosphoSitePlus;EPSD	TCGA;COSMIC	54.510	Down-regulation
CMGC_CDK_CDK4_CDK6_ST	Q16875	PFKFB3	Q00534	CDK6	T486	A489T	489	Missense	distal	3	no	54.468	55.290	EPSD	TCGA;COSMIC	54.510	Gain
CMGC_CDK_CDK4_CDK6_ST	P06748	NPM1	Q00534	CDK6	S10	D3Y	3	Missense	distal	-7	no	80.890	81.095	EPSD	TCGA	54.510	Up-regulation
CMGC_CDK_CDK4_CDK6_ST	P06748	NPM1	Q00534	CDK6	S10	L12M	12	Missense	proximal	2	no	80.890	80.868	EPSD	TCGA;ICGC;COSMIC	54.510	Down-regulation
CMGC_CDK_CDK4_CDK6_ST	P06748	NPM1	Q00534	CDK6	S10	S4L	4	Missense	distal	-6	no	80.890	81.120	EPSD	TCGA;ICGC;COSMIC	54.510	Up-regulation
CMGC_CDK_CDK4_CDK6_ST	P06748	NPM1	Q00534	CDK6	S70	K73Q	73	Missense	distal	3	no	85.210	83.976	EPSD	TCGA;ICGC;COSMIC	54.510	Down-regulation
CMGC_CDK_CDK4_CDK6_ST	P06748	NPM1	Q00534	CDK6	T95	E93K	93	Missense	proximal	-2	no	84.970	84.951	EPSD	TCGA;ICGC	54.510	Down-regulation
CMGC_CDK_CDK4_CDK6_ST	P06748	NPM1	Q00534	CDK6	T199	I196V	196	Missense	distal	-3	no	86.828	86.800	PhosphoSitePlus	TCGA;ICGC;COSMIC	54.510	Down-regulation
CMGC_CDK_CDK4_CDK6_ST	P06748	NPM1	Q00534	CDK6	S217	D213N	213	Missense	distal	-4	no	56.530	56.888	EPSD	TCGA;ICGC;COSMIC	54.510	Up-regulation
CMGC_CDK_CDK4_CDK6_ST	P06748	NPM1	Q00534	CDK6	S217	P216S	216	Missense	proximal	-1	no	56.530	56.519	EPSD	TCGA;ICGC;COSMIC	54.510	Down-regulation
CMGC_CDK_CDK4_CDK6_ST	P06748	NPM1	Q00534	CDK6	T219	D213N	213	Missense	distal	-6	no	88.146	88.084	EPSD	TCGA;ICGC;COSMIC	54.510	Down-regulation
CMGC_CDK_CDK4_CDK6_ST	P06748	NPM1	Q00534	CDK6	T219	P216S	216	Missense	distal	-3	no	88.146	88.214	EPSD	TCGA;ICGC;COSMIC	54.510	Up-regulation
CMGC_CDK_CDK4_CDK6_ST	P06748	NPM1	Q00534	CDK6	T234	K239N	239	Missense	distal	5	no	86.772	86.720	EPSD	TCGA;ICGC;COSMIC	54.510	Down-regulation
CMGC_CDK_CDK4_CDK6_ST	P06748	NPM1	Q00534	CDK6	T237	K239N	239	Missense	proximal	2	no	85.136	85.157	EPSD	TCGA;ICGC;COSMIC	54.510	Up-regulation
CMGC_CDK_CDK4_CDK6_ST	P06748	NPM1	Q00534	CDK6	S242	K239N	239	Missense	distal	-3	no	56.489	56.526	EPSD	TCGA;ICGC;COSMIC	54.510	Up-regulation
CMGC_CDK_CDK8_CDK8_ST	Q15797	SMAD1	P49336	CDK8	S132	R129K	129	Missense	distal	-3	no	32.431	32.207	EPSD	TCGA;ICGC;COSMIC	26.151	Down-regulation
CMGC_CDK_CDK8_CDK8_ST	Q15797	SMAD1	P49336	CDK8	S132	L139V	139	Missense	distal	7	no	32.431	33.221	EPSD	TCGA;ICGC;COSMIC	26.151	Up-regulation
CMGC_CDK_CDK8_CDK8_ST	Q15797	SMAD1	P49336	CDK8	S187	S190T	190	Missense	distal	3	no	51.000	50.473	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	26.151	Down-regulation
CMGC_CDK_CDK8_CDK8_ST	Q15797	SMAD1	P49336	CDK8	S195	G197V	197	Missense	proximal	2	no	50.921	48.654	PhosphoSitePlus;EPSD	TCGA;ICGC;COSMIC	26.151	Down-regulation
CMGC_CDK_CDK8_CDK8_ST	Q15797	SMAD1	P49336	CDK8	S195	S190T	190	Missense	distal	-5	no	50.921	50.713	PhosphoSitePlus;EPSD	TCGA;ICGC;COSMIC	26.151	Down-regulation
CMGC_CDK_CDK8_CDK8_ST	Q15797	SMAD1	P49336	CDK8	S214	D221G	221	Missense	distal	7	no	48.601	47.604	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	26.151	Down-regulation
CMGC_CDK_CDK8_CDK8_ST	Q15797	SMAD1	P49336	CDK8	S321	R319Q	319	Missense	proximal	-2	no	27.550	16.917	EPSD	TCGA;ICGC;COSMIC	26.151	Loss
CMGC_CDK_CDK8_CDK8_ST	Q15797	SMAD1	P49336	CDK8	S321	N318D	318	Missense	distal	-3	no	27.550	27.499	EPSD	TCGA;ICGC;COSMIC	26.151	Down-regulation
CMGC_CDK_CDK8_CDK8_ST	P46531	NOTCH1	P49336	CDK8	T535	K538N	538	Missense	distal	3	no	31.052	29.214	EPSD	TCGA;ICGC;COSMIC	26.151	Down-regulation
CMGC_CDK_CDK8_CDK8_ST	P46531	NOTCH1	P49336	CDK8	T535	C532Y	532	Missense	distal	-3	no	31.052	31.545	EPSD	TCGA	26.151	Up-regulation
CMGC_CDK_CDK8_CDK8_ST	P46531	NOTCH1	P49336	CDK8	T535	A541V	541	Missense	distal	6	no	31.052	31.295	EPSD	TCGA;ICGC;COSMIC	26.151	Up-regulation
CMGC_CDK_CDK8_CDK8_ST	P46531	NOTCH1	P49336	CDK8	T1861	S1856F	1856	Missense	distal	-5	no	28.750	28.429	EPSD	TCGA;ICGC;COSMIC	26.151	Down-regulation
CMGC_CDK_CDK8_CDK8_ST	P46531	NOTCH1	P49336	CDK8	T1861	R1854H	1854	Missense	distal	-7	no	28.750	28.760	EPSD	TCGA;ICGC;COSMIC;GDSC;CCLE	26.151	Up-regulation
CMGC_CDK_CDK8_CDK8_ST	P46531	NOTCH1	P49336	CDK8	T1861	P1862L	1862	Missense	proximal	1	no	28.750	2.896	EPSD	TCGA;ICGC;COSMIC	26.151	Loss
CMGC_CDK_CDK8_CDK8_ST	P46531	NOTCH1	P49336	CDK8	S1939	R1937H	1937	Missense	proximal	-2	no	24.670	26.573	EPSD	TCGA;ICGC;COSMIC	26.151	Gain
CMGC_CDK_CDK8_CDK8_ST	P46531	NOTCH1	P49336	CDK8	S1941	R1940H	1940	Missense	proximal	-1	no	27.022	26.756	EPSD	TCGA;ICGC;COSMIC	26.151	Down-regulation
CMGC_CDK_CDK8_CDK8_ST	P46531	NOTCH1	P49336	CDK8	S1941	R1946H	1946	Missense	distal	5	no	27.022	25.767	EPSD	TCGA;ICGC;COSMIC	26.151	Loss
CMGC_CDK_CDK8_CDK8_ST	P46531	NOTCH1	P49336	CDK8	S1941	D1942V	1942	Missense	proximal	1	no	27.022	23.302	EPSD	TCGA;ICGC;COSMIC	26.151	Loss
CMGC_CDK_CDK8_CDK8_ST	P46531	NOTCH1	P49336	CDK8	S1941	R1937H	1937	Missense	distal	-4	no	27.022	25.341	EPSD	TCGA;ICGC;COSMIC	26.151	Loss
CMGC_CDK_CDK8_CDK8_ST	P46531	NOTCH1	P49336	CDK8	S1941	A1936T	1936	Missense	distal	-5	no	27.022	27.044	EPSD	TCGA;ICGC;COSMIC	26.151	Up-regulation
CMGC_CDK_CDK8_CDK8_ST	P46531	NOTCH1	P49336	CDK8	S1941	L1934M	1934	Missense	distal	-7	no	27.022	26.981	EPSD	TCGA;ICGC;COSMIC	26.151	Down-regulation
CMGC_CDK_CDK8_CDK8_ST	P46531	NOTCH1	P49336	CDK8	S2162	S2163I	2163	Missense	proximal	1	no	27.147	7.766	EPSD	TCGA;ICGC;COSMIC	26.151	Loss
CMGC_CDK_CDK8_CDK8_ST	P46531	NOTCH1	P49336	CDK8	S2162	R2159C	2159	Missense	distal	-3	no	27.147	26.720	EPSD	TCGA;ICGC;COSMIC	26.151	Down-regulation
CMGC_CDK_CDK8_CDK8_ST	P46531	NOTCH1	P49336	CDK8	S2163	S2163I	2163	Missense	central	0	yes	41.287	0.000	EPSD	TCGA;ICGC;COSMIC	26.151	Loss
CMGC_CDK_CDK8_CDK8_ST	P46531	NOTCH1	P49336	CDK8	S2163	R2159C	2159	Missense	distal	-4	no	41.287	39.336	EPSD	TCGA;ICGC;COSMIC	26.151	Down-regulation
CMGC_CDK_CDK8_CDK8_ST	P46531	NOTCH1	P49336	CDK8	S2215	V2213L	2213	Missense	proximal	-2	no	40.600	41.148	EPSD	TCGA;ICGC;COSMIC	26.151	Up-regulation
CMGC_CDK_CDK8_CDK8_ST	P46531	NOTCH1	P49336	CDK8	S2215	P2222L	2222	Missense	distal	7	no	40.600	39.580	EPSD	TCGA;ICGC;COSMIC;CCLE	26.151	Down-regulation
CMGC_CDK_CDK8_CDK8_ST	P46531	NOTCH1	P49336	CDK8	S2215	P2222S	2222	Missense	distal	7	no	40.600	40.399	EPSD	TCGA;ICGC;COSMIC	26.151	Down-regulation
CMGC_CDK_CDK8_CDK8_ST	P46531	NOTCH1	P49336	CDK8	S2221	P2222L	2222	Missense	proximal	1	no	37.631	11.778	EPSD	TCGA;ICGC;COSMIC;CCLE	26.151	Loss
CMGC_CDK_CDK8_CDK8_ST	P46531	NOTCH1	P49336	CDK8	S2221	P2222S	2222	Missense	proximal	1	no	37.631	23.404	EPSD	TCGA;ICGC;COSMIC	26.151	Loss
CMGC_CDK_CDK8_CDK8_ST	P46531	NOTCH1	P49336	CDK8	S2221	P2227S	2227	Missense	distal	6	no	37.631	38.080	EPSD	TCGA;ICGC;COSMIC	26.151	Up-regulation
CMGC_CDK_CDK8_CDK8_ST	P46531	NOTCH1	P49336	CDK8	S2513	P2514T	2514	Missense	proximal	1	no	42.769	32.184	PhosphoSitePlus;EPSD	TCGA;ICGC;COSMIC	26.151	Down-regulation
CMGC_CDK_CDK8_CDK8_ST	P46531	NOTCH1	P49336	CDK8	S2516	S2521F	2521	Missense	distal	5	no	48.751	47.488	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	26.151	Down-regulation
CMGC_CDK_CDK8_CDK8_ST	P46531	NOTCH1	P49336	CDK8	S2516	S2523L	2523	Missense	distal	7	no	48.751	47.932	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC;GDSC;CCLE	26.151	Down-regulation
CMGC_CDK_CDK8_CDK8_ST	P46531	NOTCH1	P49336	CDK8	S2516	P2514T	2514	Missense	proximal	-2	no	48.751	42.616	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	26.151	Down-regulation
CMGC_CDK_CDK8_CDK8_ST	P46531	NOTCH1	P49336	CDK8	S2524	S2521F	2521	Missense	distal	-3	no	35.106	35.119	EPSD	TCGA;ICGC;COSMIC	26.151	Up-regulation
CMGC_CDK_CDK8_CDK8_ST	P46531	NOTCH1	P49336	CDK8	S2524	S2523L	2523	Missense	proximal	-1	no	35.106	35.097	EPSD	TCGA;ICGC;COSMIC;GDSC;CCLE	26.151	Down-regulation
CMGC_CDK_CDK8_CDK8_ST	P84022	SMAD3	P49336	CDK8	T179	E178D	178	Missense	proximal	-1	no	49.631	49.692	EPSD;PhosphoSitePlus	TCGA;COSMIC	26.151	Up-regulation
CMGC_CDK_CDK8_CDK8_ST	P84022	SMAD3	P49336	CDK8	S204	S204Y	204	Missense	central	0	yes	32.440	0.000	EPSD	TCGA;ICGC;COSMIC	26.151	Loss
CMGC_CDK_CDK8_CDK8_ST	P84022	SMAD3	P49336	CDK8	S204	S199N	199	Missense	distal	-5	no	32.440	32.138	EPSD	TCGA	26.151	Down-regulation
CMGC_CDK_CDK8_CDK8_ST	P84022	SMAD3	P49336	CDK8	S208	S204Y	204	Missense	distal	-4	no	50.292	48.562	PhosphoSitePlus;EPSD	TCGA;ICGC;COSMIC	26.151	Down-regulation
CMGC_CDK_CDK8_CDK8_ST	P84022	SMAD3	P49336	CDK8	S416	S416F	416	Missense	central	0	yes	27.595	0.000	EPSD	TCGA;ICGC;COSMIC	26.151	Loss
CMGC_CDK_CDK8_CDK8_ST	P84022	SMAD3	P49336	CDK8	S416	S418I	418	Missense	proximal	2	no	27.595	28.540	EPSD	TCGA;COSMIC	26.151	Up-regulation
CMGC_CDK_CDK8_CDK8_ST	P84022	SMAD3	P49336	CDK8	S416	R420H	420	Missense	distal	4	no	27.595	27.363	EPSD	TCGA;ICGC;COSMIC	26.151	Down-regulation
CMGC_CDK_CDK8_CDK8_ST	P84022	SMAD3	P49336	CDK8	S416	S423R	423	Missense	distal	7	no	27.595	27.639	EPSD	TCGA;ICGC;COSMIC	26.151	Up-regulation
CMGC_CDK_CDK8_CDK8_ST	P84022	SMAD3	P49336	CDK8	S416	P417L	417	Missense	proximal	1	no	27.595	1.741	EPSD	TCGA;ICGC;COSMIC	26.151	Loss
CMGC_CDK_CDK8_CDK8_ST	P84022	SMAD3	P49336	CDK8	S416	S418N	418	Missense	proximal	2	no	27.595	27.765	EPSD	TCGA;ICGC;COSMIC	26.151	Up-regulation
CMGC_CDK_CDK8_CDK8_ST	Q01094	E2F1	P49336	CDK8	S121	E124Q	124	Missense	distal	3	no	29.253	28.959	EPSD	TCGA;ICGC;COSMIC	26.151	Down-regulation
CMGC_CDK_CDK8_CDK8_ST	Q01094	E2F1	P49336	CDK8	S121	R127H	127	Missense	distal	6	no	29.253	29.577	EPSD	TCGA;ICGC;COSMIC;GDSC;CCLE	26.151	Up-regulation
CMGC_CDK_CDK8_CDK8_ST	Q01094	E2F1	P49336	CDK8	S307	I306V	306	Missense	proximal	-1	no	31.092	31.424	EPSD	TCGA;ICGC;COSMIC	26.151	Up-regulation
CMGC_CDK_CDK8_CDK8_ST	Q01094	E2F1	P49336	CDK8	S340	P346L	346	Missense	distal	6	no	29.318	30.649	EPSD	TCGA;ICGC;COSMIC	26.151	Up-regulation
CMGC_CDK_CDK8_CDK8_ST	Q01094	E2F1	P49336	CDK8	S403	H406Y	406	Missense	distal	3	no	31.917	32.107	EPSD	TCGA;ICGC;COSMIC	26.151	Up-regulation
CMGC_CDK_CDK8_CDK8_ST	Q01094	E2F1	P49336	CDK8	T433	D426N	426	Missense	distal	-7	no	26.964	26.970	EPSD	TCGA;ICGC	26.151	Up-regulation
CMGC_CDK_CDK8_CDK8_ST	P51946	CCNH	P49336	CDK8	S121	G127R	127	Missense	distal	6	no	26.372	24.828	EPSD	TCGA;ICGC;COSMIC	26.151	Loss
CMGC_CDK_CDK8_CDK8_ST	P51946	CCNH	P49336	CDK8	S121	K114N	114	Missense	distal	-7	no	26.372	26.391	EPSD	TCGA;ICGC	26.151	Up-regulation
CMGC_CDK_CDK8_CDK8_ST	P51946	CCNH	P49336	CDK8	S132	G127R	127	Missense	distal	-5	no	31.091	31.685	EPSD	TCGA;ICGC;COSMIC	26.151	Up-regulation
CMGC_CDK_CDK8_CDK8_ST	P51946	CCNH	P49336	CDK8	S304	V303I	303	Missense	proximal	-1	no	39.633	39.301	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	26.151	Down-regulation
TK_Fak_PTK2_Y	P23634	ATP2B4	Q05397	PTK2	Y487	Y487D	487	Missense	central	0	yes	0.000	0.000	EPSD	TCGA;ICGC;COSMIC	0.000	Loss
TK_Fak_PTK2_Y	O75962	TRIO	Q05397	PTK2	Y2796	Y2796C	2796	Missense	central	0	yes	0.000	0.000	PhosphoSitePlus	TCGA;COSMIC	0.000	Loss
AGC_RSK_RSKp90_RPS6KA1_ST	O95071	UBR5	Q15418	RPS6KA1	S115	E118Q	118	Missense	distal	3	no	1.788	1.773	EPSD	TCGA;ICGC;COSMIC	1.787	Loss
AGC_RSK_RSKp90_RPS6KA1_ST	O95071	UBR5	Q15418	RPS6KA1	S115	L120V	120	Missense	distal	5	no	1.788	1.929	EPSD	TCGA;ICGC;COSMIC	1.787	Up-regulation
AGC_RSK_RSKp90_RPS6KA1_ST	O95071	UBR5	Q15418	RPS6KA1	S115	D109N	109	Missense	distal	-6	no	1.788	1.778	EPSD	TCGA;COSMIC	1.787	Loss
AGC_RSK_RSKp90_RPS6KA1_ST	O95071	UBR5	Q15418	RPS6KA1	S115	L114I	114	Missense	proximal	-1	no	1.788	1.705	EPSD	TCGA;ICGC	1.787	Loss
AGC_RSK_RSKp90_RPS6KA1_ST	O95071	UBR5	Q15418	RPS6KA1	S133	G138A	138	Missense	distal	5	no	1.567	1.846	EPSD	TCGA;ICGC;COSMIC	1.787	Gain
AGC_RSK_RSKp90_RPS6KA1_ST	O95071	UBR5	Q15418	RPS6KA1	S293	L299V	299	Missense	distal	6	no	2.922	2.866	EPSD	TCGA;ICGC;COSMIC	1.787	Down-regulation
AGC_RSK_RSKp90_RPS6KA1_ST	O95071	UBR5	Q15418	RPS6KA1	S293	R290M	290	Missense	distal	-3	no	2.922	2.708	EPSD	TCGA;ICGC;COSMIC	1.787	Down-regulation
AGC_RSK_RSKp90_RPS6KA1_ST	O95071	UBR5	Q15418	RPS6KA1	S293	R295Q	295	Missense	proximal	2	no	2.922	2.687	EPSD	TCGA;ICGC;COSMIC;GDSC;CCLE	1.787	Down-regulation
AGC_RSK_RSKp90_RPS6KA1_ST	O95071	UBR5	Q15418	RPS6KA1	S305	E310D	310	Missense	distal	5	no	2.894	2.819	EPSD	TCGA;COSMIC	1.787	Down-regulation
AGC_RSK_RSKp90_RPS6KA1_ST	O95071	UBR5	Q15418	RPS6KA1	S305	R309H	309	Missense	distal	4	no	2.894	2.934	EPSD	TCGA;COSMIC	1.787	Up-regulation
AGC_RSK_RSKp90_RPS6KA1_ST	O95071	UBR5	Q15418	RPS6KA1	S305	L299V	299	Missense	distal	-6	no	2.894	2.207	EPSD	TCGA;ICGC;COSMIC	1.787	Down-regulation
AGC_RSK_RSKp90_RPS6KA1_ST	O95071	UBR5	Q15418	RPS6KA1	T335	D329H	329	Missense	distal	-6	no	1.455	1.902	EPSD	TCGA;COSMIC	1.787	Gain
AGC_RSK_RSKp90_RPS6KA1_ST	O95071	UBR5	Q15418	RPS6KA1	S695	D698H	698	Missense	distal	3	no	2.186	2.212	EPSD	TCGA;COSMIC	1.787	Up-regulation
AGC_RSK_RSKp90_RPS6KA1_ST	O95071	UBR5	Q15418	RPS6KA1	S695	S694I	694	Missense	proximal	-1	no	2.186	1.892	EPSD	TCGA;COSMIC	1.787	Down-regulation
AGC_RSK_RSKp90_RPS6KA1_ST	O95071	UBR5	Q15418	RPS6KA1	S695	P697L	697	Missense	proximal	2	no	2.186	2.003	EPSD	TCGA;COSMIC	1.787	Down-regulation
AGC_RSK_RSKp90_RPS6KA1_ST	O95071	UBR5	Q15418	RPS6KA1	S695	A699T	699	Missense	distal	4	no	2.186	2.203	EPSD	TCGA;COSMIC	1.787	Up-regulation
AGC_RSK_RSKp90_RPS6KA1_ST	O95071	UBR5	Q15418	RPS6KA1	S985	R984Q	984	Missense	proximal	-1	no	1.663	1.797	EPSD	TCGA;COSMIC	1.787	Gain
AGC_RSK_RSKp90_RPS6KA1_ST	O95071	UBR5	Q15418	RPS6KA1	T1115	A1120V	1120	Missense	distal	5	no	1.869	1.953	EPSD	TCGA;ICGC;COSMIC	1.787	Up-regulation
AGC_RSK_RSKp90_RPS6KA1_ST	O95071	UBR5	Q15418	RPS6KA1	T1115	T1115P	1115	Missense	central	0	yes	1.869	0.000	EPSD	TCGA;ICGC;COSMIC	1.787	Loss
AGC_RSK_RSKp90_RPS6KA1_ST	O95071	UBR5	Q15418	RPS6KA1	T1115	A1108V	1108	Missense	distal	-7	no	1.869	1.831	EPSD	TCGA;COSMIC	1.787	Down-regulation
AGC_RSK_RSKp90_RPS6KA1_ST	O95071	UBR5	Q15418	RPS6KA1	S1119	A1120V	1120	Missense	proximal	1	no	2.058	1.922	EPSD	TCGA;ICGC;COSMIC	1.787	Down-regulation
AGC_RSK_RSKp90_RPS6KA1_ST	O95071	UBR5	Q15418	RPS6KA1	S1119	T1115P	1115	Missense	distal	-4	no	2.058	2.141	EPSD	TCGA;ICGC;COSMIC	1.787	Up-regulation
AGC_RSK_RSKp90_RPS6KA1_ST	O95071	UBR5	Q15418	RPS6KA1	T1404	D1399V	1399	Missense	distal	-5	no	3.233	3.193	EPSD	TCGA;ICGC;COSMIC	1.787	Down-regulation
AGC_RSK_RSKp90_RPS6KA1_ST	O95071	UBR5	Q15418	RPS6KA1	S1549	R1555W	1555	Missense	distal	6	no	3.013	2.903	EPSD	TCGA;COSMIC	1.787	Down-regulation
AGC_RSK_RSKp90_RPS6KA1_ST	O95071	UBR5	Q15418	RPS6KA1	S1549	R1547C	1547	Missense	proximal	-2	no	3.013	3.101	EPSD	TCGA;COSMIC	1.787	Up-regulation
AGC_RSK_RSKp90_RPS6KA1_ST	O95071	UBR5	Q15418	RPS6KA1	S1549	N1542H	1542	Missense	distal	-7	no	3.013	3.017	EPSD	TCGA;COSMIC	1.787	Up-regulation
AGC_RSK_RSKp90_RPS6KA1_ST	O95071	UBR5	Q15418	RPS6KA1	S1733	S1735C	1735	Missense	proximal	2	no	1.950	2.211	EPSD	TCGA;COSMIC	1.787	Up-regulation
AGC_RSK_RSKp90_RPS6KA1_ST	O95071	UBR5	Q15418	RPS6KA1	S1733	S1728I	1728	Missense	distal	-5	no	1.950	1.952	EPSD	TCGA;COSMIC	1.787	Up-regulation
AGC_RSK_RSKp90_RPS6KA1_ST	O95071	UBR5	Q15418	RPS6KA1	T1734	S1735C	1735	Missense	proximal	1	no	1.862	1.894	EPSD	TCGA;COSMIC	1.787	Up-regulation
AGC_RSK_RSKp90_RPS6KA1_ST	O95071	UBR5	Q15418	RPS6KA1	T1734	S1728I	1728	Missense	distal	-6	no	1.862	2.123	EPSD	TCGA;COSMIC	1.787	Up-regulation
AGC_RSK_RSKp90_RPS6KA1_ST	O95071	UBR5	Q15418	RPS6KA1	S1776	S1775N	1775	Missense	proximal	-1	no	1.896	1.835	EPSD	TCGA;COSMIC	1.787	Down-regulation
AGC_RSK_RSKp90_RPS6KA1_ST	O95071	UBR5	Q15418	RPS6KA1	S1776	S1775R	1775	Missense	proximal	-1	no	1.896	1.631	EPSD	TCGA;COSMIC	1.787	Loss
AGC_RSK_RSKp90_RPS6KA1_ST	O95071	UBR5	Q15418	RPS6KA1	S1776	A1774T	1774	Missense	proximal	-2	no	1.896	1.962	EPSD	TCGA	1.787	Up-regulation
AGC_RSK_RSKp90_RPS6KA1_ST	O95071	UBR5	Q15418	RPS6KA1	T1902	S1905R	1905	Missense	distal	3	no	2.686	2.641	EPSD	TCGA;COSMIC	1.787	Down-regulation
AGC_RSK_RSKp90_RPS6KA1_ST	O95071	UBR5	Q15418	RPS6KA1	S2241	R2238T	2238	Missense	distal	-3	no	2.102	1.651	EPSD	TCGA;COSMIC	1.787	Loss
AGC_RSK_RSKp90_RPS6KA1_ST	O95071	UBR5	Q15418	RPS6KA1	S2356	A2354V	2354	Missense	proximal	-2	no	1.849	1.907	EPSD	TCGA;ICGC;COSMIC	1.787	Up-regulation
AGC_RSK_RSKp90_RPS6KA1_ST	O95071	UBR5	Q15418	RPS6KA1	S2437	S2437Y	2437	Missense	central	0	yes	2.475	0.000	EPSD	TCGA;ICGC	1.787	Loss
AGC_RSK_RSKp90_RPS6KA1_ST	O95071	UBR5	Q15418	RPS6KA1	S2469	D2463H	2463	Missense	distal	-6	no	1.689	2.136	EPSD	TCGA;ICGC;COSMIC	1.787	Gain
AGC_RSK_RSKp90_RPS6KA1_ST	O95071	UBR5	Q15418	RPS6KA1	S2470	N2477T	2477	Missense	distal	7	no	2.581	2.449	EPSD	TCGA;ICGC;COSMIC	1.787	Down-regulation
AGC_RSK_RSKp90_RPS6KA1_ST	O95071	UBR5	Q15418	RPS6KA1	S2470	D2463H	2463	Missense	distal	-7	no	2.581	2.569	EPSD	TCGA;ICGC;COSMIC	1.787	Down-regulation
AGC_RSK_RSKp90_RPS6KA1_ST	Q13164	MAPK7	Q15418	RPS6KA1	S337	R335H	335	Missense	proximal	-2	no	1.768	1.856	EPSD	TCGA;ICGC;COSMIC	1.787	Gain
AGC_RSK_RSKp90_RPS6KA1_ST	Q13164	MAPK7	Q15418	RPS6KA1	S433	A430V	430	Missense	distal	-3	no	2.033	1.467	EPSD	TCGA;ICGC;COSMIC	1.787	Loss
AGC_RSK_RSKp90_RPS6KA1_ST	Q13164	MAPK7	Q15418	RPS6KA1	S486	S486Y	486	Missense	central	0	yes	2.773	0.000	EPSD	TCGA	1.787	Loss
AGC_RSK_RSKp90_RPS6KA1_ST	Q13164	MAPK7	Q15418	RPS6KA1	S486	R488M	488	Missense	proximal	2	no	2.773	2.507	EPSD	TCGA;ICGC	1.787	Down-regulation
AGC_RSK_RSKp90_RPS6KA1_ST	O60343	TBC1D4	Q15418	RPS6KA1	S44	W39R	39	Missense	distal	-5	no	2.694	2.553	EPSD	TCGA;ICGC;COSMIC	1.787	Down-regulation
AGC_RSK_RSKp90_RPS6KA1_ST	O60343	TBC1D4	Q15418	RPS6KA1	S44	T51A	51	Missense	distal	7	no	2.694	2.690	EPSD	TCGA;ICGC;COSMIC	1.787	Down-regulation
AGC_RSK_RSKp90_RPS6KA1_ST	O60343	TBC1D4	Q15418	RPS6KA1	T568	F575L	575	Missense	distal	7	no	1.990	1.940	EPSD;PhosphoSitePlus	TCGA;ICGC;CCLE	1.787	Down-regulation
AGC_RSK_RSKp90_RPS6KA1_ST	O60343	TBC1D4	Q15418	RPS6KA1	S576	F575L	575	Missense	proximal	-1	no	1.987	1.809	EPSD	TCGA;ICGC;CCLE	1.787	Down-regulation
AGC_RSK_RSKp90_RPS6KA1_ST	O60343	TBC1D4	Q15418	RPS6KA1	S576	R577K	577	Missense	proximal	1	no	1.987	2.037	EPSD	TCGA	1.787	Up-regulation
AGC_RSK_RSKp90_RPS6KA1_ST	O60343	TBC1D4	Q15418	RPS6KA1	S631	E629Q	629	Missense	proximal	-2	no	2.054	2.068	EPSD	TCGA;ICGC;COSMIC	1.787	Up-regulation
AGC_RSK_RSKp90_RPS6KA1_ST	O60343	TBC1D4	Q15418	RPS6KA1	S631	S633F	633	Missense	proximal	2	no	2.054	2.126	EPSD	TCGA;ICGC;COSMIC	1.787	Up-regulation
AGC_RSK_RSKp90_RPS6KA1_ST	O60343	TBC1D4	Q15418	RPS6KA1	S631	E628K	628	Missense	distal	-3	no	2.054	2.010	EPSD	TCGA;ICGC;COSMIC	1.787	Down-regulation
AGC_RSK_RSKp90_RPS6KA1_ST	O60343	TBC1D4	Q15418	RPS6KA1	S702	S704F	704	Missense	proximal	2	no	1.790	1.862	EPSD	TCGA;ICGC;COSMIC	1.787	Up-regulation
AGC_RSK_RSKp90_RPS6KA1_ST	O60343	TBC1D4	Q15418	RPS6KA1	S702	A705T	705	Missense	distal	3	no	1.790	1.869	EPSD	TCGA;ICGC;COSMIC	1.787	Up-regulation
AGC_RSK_RSKp90_RPS6KA1_ST	O60343	TBC1D4	Q15418	RPS6KA1	S702	F703L	703	Missense	proximal	1	no	1.790	1.823	EPSD	TCGA;ICGC	1.787	Up-regulation
AGC_RSK_RSKp90_RPS6KA1_ST	O60343	TBC1D4	Q15418	RPS6KA1	S787	P788S	788	Missense	proximal	1	no	2.464	2.418	EPSD	TCGA;COSMIC	1.787	Down-regulation
AGC_RSK_RSKp90_RPS6KA1_ST	O60343	TBC1D4	Q15418	RPS6KA1	T811	L808P	808	Missense	distal	-3	no	2.128	1.543	EPSD	TCGA;COSMIC	1.787	Loss
AGC_RSK_RSKp90_RPS6KA1_ST	O60343	TBC1D4	Q15418	RPS6KA1	T811	P816L	816	Missense	distal	5	no	2.128	2.116	EPSD	TCGA;COSMIC	1.787	Down-regulation
AGC_RSK_RSKp90_RPS6KA1_ST	O60343	TBC1D4	Q15418	RPS6KA1	T811	E814D	814	Missense	distal	3	no	2.128	2.136	EPSD	TCGA	1.787	Up-regulation
AGC_RSK_RSKp90_RPS6KA1_ST	O60343	TBC1D4	Q15418	RPS6KA1	S1207	E1203D	1203	Missense	distal	-4	no	1.857	1.702	EPSD	TCGA;COSMIC	1.787	Loss
AGC_RSK_RSKp90_RPS6KA1_ST	O60343	TBC1D4	Q15418	RPS6KA1	S1207	K1201E	1201	Missense	distal	-6	no	1.857	1.382	EPSD	TCGA;COSMIC	1.787	Loss
AGC_RSK_RSKp90_RPS6KA1_ST	Q92934	BAD	Q15418	RPS6KA1	S75	S71I	71	Missense	distal	-4	no	3.978	3.989	PhosphoSitePlus	TCGA;ICGC;COSMIC	1.787	Up-regulation
AGC_RSK_RSKp90_RPS6KA1_ST	Q92934	BAD	Q15418	RPS6KA1	S124	M117I	117	Missense	distal	-7	no	2.480	2.435	EPSD	TCGA;ICGC;COSMIC	1.787	Down-regulation
AGC_RSK_RSKp90_RPS6KA1_ST	Q92934	BAD	Q15418	RPS6KA1	S124	R131H	131	Missense	distal	7	no	2.480	2.295	EPSD	TCGA;ICGC;COSMIC	1.787	Down-regulation
AGC_RSK_RSKp90_RPS6KA1_ST	P19634	SLC9A1	Q15418	RPS6KA1	T42	T45I	45	Missense	distal	3	no	2.718	2.657	EPSD	TCGA;ICGC	1.787	Down-regulation
AGC_RSK_RSKp90_RPS6KA1_ST	P19634	SLC9A1	Q15418	RPS6KA1	T42	S49A	49	Missense	distal	7	no	2.718	2.671	EPSD	TCGA;ICGC;COSMIC	1.787	Down-regulation
AGC_RSK_RSKp90_RPS6KA1_ST	Q8IX03	WWC1	Q15418	RPS6KA1	S262	S265C	265	Missense	distal	3	no	1.847	1.892	EPSD	TCGA;ICGC;COSMIC	1.787	Up-regulation
AGC_RSK_RSKp90_RPS6KA1_ST	Q8IX03	WWC1	Q15418	RPS6KA1	S262	H256Y	256	Missense	distal	-6	no	1.847	1.300	EPSD	TCGA;ICGC;COSMIC	1.787	Loss
AGC_RSK_RSKp90_RPS6KA1_ST	Q8IX03	WWC1	Q15418	RPS6KA1	S262	S269L	269	Missense	distal	7	no	1.847	1.855	EPSD	TCGA;ICGC;COSMIC	1.787	Up-regulation
AGC_RSK_RSKp90_RPS6KA1_ST	Q8IX03	WWC1	Q15418	RPS6KA1	S262	S257L	257	Missense	distal	-5	no	1.847	1.986	EPSD	TCGA;ICGC;COSMIC	1.787	Up-regulation
AGC_RSK_RSKp90_RPS6KA1_ST	Q8IX03	WWC1	Q15418	RPS6KA1	S530	S525F	525	Missense	distal	-5	no	2.098	2.225	EPSD	TCGA;ICGC;COSMIC	1.787	Up-regulation
AGC_RSK_RSKp90_RPS6KA1_ST	Q8IX03	WWC1	Q15418	RPS6KA1	S530	R537C	537	Missense	distal	7	no	2.098	2.187	EPSD	TCGA;ICGC;COSMIC	1.787	Up-regulation
AGC_RSK_RSKp90_RPS6KA1_ST	Q8IX03	WWC1	Q15418	RPS6KA1	S530	P528S	528	Missense	proximal	-2	no	2.098	2.088	EPSD	TCGA;ICGC;COSMIC	1.787	Down-regulation
AGC_RSK_RSKp90_RPS6KA1_ST	Q8IX03	WWC1	Q15418	RPS6KA1	S530	S523F	523	Missense	distal	-7	no	2.098	2.077	EPSD	TCGA;ICGC;COSMIC	1.787	Down-regulation
AGC_RSK_RSKp90_RPS6KA1_ST	Q8IX03	WWC1	Q15418	RPS6KA1	S530	P536S	536	Missense	distal	6	no	2.098	2.192	EPSD	TCGA;ICGC;COSMIC	1.787	Up-regulation
AGC_RSK_RSKp90_RPS6KA1_ST	Q8IX03	WWC1	Q15418	RPS6KA1	S530	S533F	533	Missense	distal	3	no	2.098	2.157	EPSD	TCGA;ICGC;COSMIC	1.787	Up-regulation
AGC_RSK_RSKp90_RPS6KA1_ST	Q8IX03	WWC1	Q15418	RPS6KA1	S530	M531I	531	Missense	proximal	1	no	2.098	2.158	EPSD	TCGA;ICGC;COSMIC	1.787	Up-regulation
AGC_RSK_RSKp90_RPS6KA1_ST	Q8IX03	WWC1	Q15418	RPS6KA1	T532	S525F	525	Missense	distal	-7	no	1.791	1.769	EPSD	TCGA;ICGC;COSMIC	1.787	Loss
AGC_RSK_RSKp90_RPS6KA1_ST	Q8IX03	WWC1	Q15418	RPS6KA1	T532	R537C	537	Missense	distal	5	no	1.791	1.590	EPSD	TCGA;ICGC;COSMIC	1.787	Loss
AGC_RSK_RSKp90_RPS6KA1_ST	Q8IX03	WWC1	Q15418	RPS6KA1	T532	P528S	528	Missense	distal	-4	no	1.791	1.600	EPSD	TCGA;ICGC;COSMIC	1.787	Loss
AGC_RSK_RSKp90_RPS6KA1_ST	Q8IX03	WWC1	Q15418	RPS6KA1	T532	P536S	536	Missense	distal	4	no	1.791	1.765	EPSD	TCGA;ICGC;COSMIC	1.787	Loss
AGC_RSK_RSKp90_RPS6KA1_ST	Q8IX03	WWC1	Q15418	RPS6KA1	T532	S533F	533	Missense	proximal	1	no	1.791	1.853	EPSD	TCGA;ICGC;COSMIC	1.787	Up-regulation
AGC_RSK_RSKp90_RPS6KA1_ST	Q8IX03	WWC1	Q15418	RPS6KA1	T532	M531I	531	Missense	proximal	-1	no	1.791	1.583	EPSD	TCGA;ICGC;COSMIC	1.787	Loss
AGC_RSK_RSKp90_RPS6KA1_ST	Q8IX03	WWC1	Q15418	RPS6KA1	S623	A621T	621	Missense	proximal	-2	no	2.119	2.185	EPSD	TCGA;ICGC;COSMIC	1.787	Up-regulation
AGC_RSK_RSKp90_RPS6KA1_ST	Q8IX03	WWC1	Q15418	RPS6KA1	S623	E625K	625	Missense	proximal	2	no	2.119	1.989	EPSD	TCGA;ICGC;COSMIC	1.787	Down-regulation
AGC_RSK_RSKp90_RPS6KA1_ST	Q8IX03	WWC1	Q15418	RPS6KA1	S623	V622I	622	Missense	proximal	-1	no	2.119	1.850	EPSD	TCGA;ICGC;COSMIC	1.787	Down-regulation
AGC_RSK_RSKp90_RPS6KA1_ST	Q8IX03	WWC1	Q15418	RPS6KA1	S644	S637F	637	Missense	distal	-7	no	2.148	2.126	EPSD	TCGA;ICGC;COSMIC	1.787	Down-regulation
AGC_RSK_RSKp90_RPS6KA1_ST	Q8IX03	WWC1	Q15418	RPS6KA1	S833	K827N	827	Missense	distal	-6	no	1.951	1.400	EPSD	TCGA;ICGC;COSMIC	1.787	Loss
AGC_RSK_RSKp90_RPS6KA1_ST	Q8IX03	WWC1	Q15418	RPS6KA1	S841	E845K	845	Missense	distal	4	no	2.867	2.885	EPSD	TCGA;ICGC;COSMIC	1.787	Up-regulation
AGC_RSK_RSKp90_RPS6KA1_ST	Q8IX03	WWC1	Q15418	RPS6KA1	S947	R941W	941	Missense	distal	-6	no	1.558	1.892	PhosphoSitePlus;EPSD	TCGA;ICGC;COSMIC	1.787	Gain
AGC_RSK_RSKp90_RPS6KA1_ST	Q8IX03	WWC1	Q15418	RPS6KA1	S974	S967N	967	Missense	distal	-7	no	1.905	1.890	EPSD	TCGA;ICGC;COSMIC	1.787	Down-regulation
AGC_RSK_RSKp90_RPS6KA1_ST	Q8IX03	WWC1	Q15418	RPS6KA1	S974	V968I	968	Missense	distal	-6	no	1.905	2.354	EPSD	TCGA;ICGC;COSMIC	1.787	Up-regulation
AGC_RSK_RSKp90_RPS6KA1_ST	Q8IX03	WWC1	Q15418	RPS6KA1	S974	R972Q	972	Missense	proximal	-2	no	1.905	1.980	EPSD	TCGA;ICGC;COSMIC;GDSC	1.787	Up-regulation
AGC_RSK_RSKp90_RPS6KA1_ST	Q8N122	RPTOR	Q15418	RPS6KA1	S854	T857M	857	Missense	distal	3	no	2.647	2.540	EPSD	TCGA;COSMIC	1.787	Down-regulation
AGC_RSK_RSKp90_RPS6KA1_ST	Q8N122	RPTOR	Q15418	RPS6KA1	S882	P879L	879	Missense	distal	-3	no	1.528	2.114	EPSD	TCGA;COSMIC	1.787	Gain
AGC_RSK_RSKp90_RPS6KA1_ST	Q8N122	RPTOR	Q15418	RPS6KA1	S1116	D1117E	1117	Missense	proximal	1	no	1.822	1.851	EPSD	TCGA;COSMIC	1.787	Up-regulation
AGC_RSK_RSKp90_RPS6KA1_ST	Q8N122	RPTOR	Q15418	RPS6KA1	S1116	A1111V	1111	Missense	distal	-5	no	1.822	1.997	EPSD	TCGA;COSMIC	1.787	Up-regulation
AGC_RSK_RSKp90_RPS6KA1_ST	Q8N122	RPTOR	Q15418	RPS6KA1	S1189	V1192I	1192	Missense	distal	3	no	2.822	2.836	EPSD	TCGA;COSMIC	1.787	Up-regulation
AGC_RSK_RSKp90_RPS6KA1_ST	Q8N122	RPTOR	Q15418	RPS6KA1	S1189	G1184A	1184	Missense	distal	-5	no	2.822	2.664	EPSD	TCGA;COSMIC	1.787	Down-regulation
AGC_RSK_RSKp90_RPS6KA1_ST	Q8N122	RPTOR	Q15418	RPS6KA1	S1189	G1188S	1188	Missense	proximal	-1	no	2.822	2.774	EPSD	TCGA;COSMIC	1.787	Down-regulation
AGC_RSK_RSKp90_RPS6KA1_ST	P50552	VASP	Q15418	RPS6KA1	S239	E242D	242	Missense	distal	3	no	2.179	2.187	EPSD	TCGA;ICGC;COSMIC	1.787	Up-regulation
AGC_RSK_RSKp90_RPS6KA1_ST	P16220	CREB1	Q15418	RPS6KA1	T104	S103A	103	Missense	proximal	-1	no	2.270	2.023	EPSD	TCGA;COSMIC	1.787	Down-regulation
AGC_RSK_RSKp90_RPS6KA1_ST	P16220	CREB1	Q15418	RPS6KA1	S133	L128I	128	Missense	distal	-5	no	5.441	5.304	PhosphoSitePlus	TCGA;COSMIC	1.787	Down-regulation
AGC_RSK_RSKp90_RPS6KA1_ST	Q2M1Z3	ARHGAP31	Q15418	RPS6KA1	S272	R268K	268	Missense	distal	-4	no	1.805	1.779	EPSD	TCGA;ICGC;COSMIC	1.787	Loss
AGC_RSK_RSKp90_RPS6KA1_ST	Q2M1Z3	ARHGAP31	Q15418	RPS6KA1	S272	R269S	269	Missense	distal	-3	no	1.805	1.402	EPSD	TCGA;ICGC;COSMIC	1.787	Loss
AGC_RSK_RSKp90_RPS6KA1_ST	Q2M1Z3	ARHGAP31	Q15418	RPS6KA1	S272	R265H	265	Missense	distal	-7	no	1.805	1.772	EPSD	TCGA;ICGC;COSMIC	1.787	Loss
AGC_RSK_RSKp90_RPS6KA1_ST	Q2M1Z3	ARHGAP31	Q15418	RPS6KA1	S272	K266N	266	Missense	distal	-6	no	1.805	1.255	EPSD	TCGA;ICGC	1.787	Loss
AGC_RSK_RSKp90_RPS6KA1_ST	Q2M1Z3	ARHGAP31	Q15418	RPS6KA1	S272	P278S	278	Missense	distal	6	no	1.805	1.899	EPSD	TCGA;ICGC;COSMIC	1.787	Up-regulation
AGC_RSK_RSKp90_RPS6KA1_ST	Q2M1Z3	ARHGAP31	Q15418	RPS6KA1	S382	G384S	384	Missense	proximal	2	no	2.612	2.455	EPSD	TCGA;ICGC;COSMIC	1.787	Down-regulation
AGC_RSK_RSKp90_RPS6KA1_ST	Q2M1Z3	ARHGAP31	Q15418	RPS6KA1	S382	T385N	385	Missense	distal	3	no	2.612	2.469	EPSD	TCGA;ICGC;COSMIC	1.787	Down-regulation
AGC_RSK_RSKp90_RPS6KA1_ST	Q2M1Z3	ARHGAP31	Q15418	RPS6KA1	S593	E586K	586	Missense	distal	-7	no	2.003	1.978	EPSD	TCGA;ICGC;COSMIC	1.787	Down-regulation
AGC_RSK_RSKp90_RPS6KA1_ST	Q2M1Z3	ARHGAP31	Q15418	RPS6KA1	S593	S596Y	596	Missense	distal	3	no	2.003	2.015	EPSD	TCGA;ICGC	1.787	Up-regulation
AGC_RSK_RSKp90_RPS6KA1_ST	Q2M1Z3	ARHGAP31	Q15418	RPS6KA1	S629	R631S	631	Missense	proximal	2	no	2.075	1.924	EPSD	TCGA;ICGC;COSMIC	1.787	Down-regulation
AGC_RSK_RSKp90_RPS6KA1_ST	Q2M1Z3	ARHGAP31	Q15418	RPS6KA1	S680	P674T	674	Missense	distal	-6	no	1.981	2.338	EPSD	TCGA;ICGC;COSMIC	1.787	Up-regulation
AGC_RSK_RSKp90_RPS6KA1_ST	Q2M1Z3	ARHGAP31	Q15418	RPS6KA1	S680	E687D	687	Missense	distal	7	no	1.981	2.030	EPSD	TCGA;ICGC;COSMIC	1.787	Up-regulation
AGC_RSK_RSKp90_RPS6KA1_ST	Q2M1Z3	ARHGAP31	Q15418	RPS6KA1	S680	L686I	686	Missense	distal	6	no	1.981	2.030	EPSD	TCGA;ICGC;COSMIC	1.787	Up-regulation
AGC_RSK_RSKp90_RPS6KA1_ST	Q2M1Z3	ARHGAP31	Q15418	RPS6KA1	S696	P692L	692	Missense	distal	-4	no	1.894	1.963	EPSD	TCGA;ICGC;COSMIC	1.787	Up-regulation
AGC_RSK_RSKp90_RPS6KA1_ST	Q2M1Z3	ARHGAP31	Q15418	RPS6KA1	S696	P692S	692	Missense	distal	-4	no	1.894	1.703	EPSD	TCGA;ICGC	1.787	Loss
AGC_RSK_RSKp90_RPS6KA1_ST	Q2M1Z3	ARHGAP31	Q15418	RPS6KA1	S957	K958R	958	Missense	proximal	1	no	1.879	1.829	EPSD	TCGA;ICGC;COSMIC	1.787	Down-regulation
AGC_RSK_RSKp90_RPS6KA1_ST	Q2M1Z3	ARHGAP31	Q15418	RPS6KA1	S957	L955P	955	Missense	proximal	-2	no	1.879	1.886	EPSD	TCGA;ICGC;COSMIC;GDSC;CCLE	1.787	Up-regulation
AGC_RSK_RSKp90_RPS6KA1_ST	Q2M1Z3	ARHGAP31	Q15418	RPS6KA1	S957	S952N	952	Missense	distal	-5	no	1.879	2.139	EPSD	TCGA;ICGC	1.787	Up-regulation
AGC_RSK_RSKp90_RPS6KA1_ST	Q2M1Z3	ARHGAP31	Q15418	RPS6KA1	S957	S957N	957	Missense	central	0	yes	1.879	0.000	EPSD	TCGA;ICGC	1.787	Loss
AGC_RSK_RSKp90_RPS6KA1_ST	Q2M1Z3	ARHGAP31	Q15418	RPS6KA1	S972	A976V	976	Missense	distal	4	no	2.080	2.031	EPSD	TCGA;ICGC;COSMIC	1.787	Down-regulation
AGC_RSK_RSKp90_RPS6KA1_ST	Q2M1Z3	ARHGAP31	Q15418	RPS6KA1	S972	L978H	978	Missense	distal	6	no	2.080	2.174	EPSD	TCGA;ICGC;COSMIC	1.787	Up-regulation
AGC_RSK_RSKp90_RPS6KA1_ST	Q2M1Z3	ARHGAP31	Q15418	RPS6KA1	S972	S973R	973	Missense	proximal	1	no	2.080	2.151	EPSD	TCGA;ICGC;COSMIC	1.787	Up-regulation
AGC_RSK_RSKp90_RPS6KA1_ST	Q2M1Z3	ARHGAP31	Q15418	RPS6KA1	S1036	E1042Q	1042	Missense	distal	6	no	1.987	1.784	EPSD	TCGA;ICGC;COSMIC	1.787	Loss
AGC_RSK_RSKp90_RPS6KA1_ST	Q2M1Z3	ARHGAP31	Q15418	RPS6KA1	S1036	A1033T	1033	Missense	distal	-3	no	1.987	1.541	EPSD	TCGA;ICGC;COSMIC	1.787	Loss
AGC_RSK_RSKp90_RPS6KA1_ST	Q2M1Z3	ARHGAP31	Q15418	RPS6KA1	S1054	I1057S	1057	Missense	distal	3	no	3.090	3.031	EPSD	TCGA;ICGC;COSMIC	1.787	Down-regulation
AGC_RSK_RSKp90_RPS6KA1_ST	Q2M1Z3	ARHGAP31	Q15418	RPS6KA1	S1054	G1061A	1061	Missense	distal	7	no	3.090	2.877	EPSD	TCGA;ICGC;COSMIC	1.787	Down-regulation
AGC_RSK_RSKp90_RPS6KA1_ST	Q2M1Z3	ARHGAP31	Q15418	RPS6KA1	S1054	Q1056H	1056	Missense	proximal	2	no	3.090	3.156	EPSD	TCGA;ICGC;COSMIC	1.787	Up-regulation
AGC_RSK_RSKp90_RPS6KA1_ST	Q2M1Z3	ARHGAP31	Q15418	RPS6KA1	S1054	G1051W	1051	Missense	distal	-3	no	3.090	3.392	EPSD	TCGA;ICGC	1.787	Up-regulation
AGC_RSK_RSKp90_RPS6KA1_ST	Q2M1Z3	ARHGAP31	Q15418	RPS6KA1	S1178	R1175H	1175	Missense	distal	-3	no	2.286	1.868	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	1.787	Down-regulation
AGC_RSK_RSKp90_RPS6KA1_ST	Q2M1Z3	ARHGAP31	Q15418	RPS6KA1	T1396	L1392F	1392	Missense	distal	-4	no	3.378	3.284	EPSD	TCGA;ICGC;COSMIC	1.787	Down-regulation
AGC_RSK_RSKp90_RPS6KA1_ST	Q9H6Z4	RANBP3	Q15418	RPS6KA1	S72	S72L	72	Missense	central	0	yes	2.294	0.000	EPSD	TCGA;ICGC;COSMIC	1.787	Loss
AGC_RSK_RSKp90_RPS6KA1_ST	Q9H6Z4	RANBP3	Q15418	RPS6KA1	S72	A67V	67	Missense	distal	-5	no	2.294	2.470	EPSD	TCGA;ICGC;COSMIC	1.787	Up-regulation
AGC_RSK_RSKp90_RPS6KA1_ST	Q9H6Z4	RANBP3	Q15418	RPS6KA1	S72	P77L	77	Missense	distal	5	no	2.294	2.282	EPSD	TCGA;COSMIC	1.787	Down-regulation
AGC_RSK_RSKp90_RPS6KA1_ST	Q9H6Z4	RANBP3	Q15418	RPS6KA1	S72	P65H	65	Missense	distal	-7	no	2.294	2.292	EPSD	TCGA;ICGC;COSMIC	1.787	Down-regulation
AGC_RSK_RSKp90_RPS6KA1_ST	Q9H6Z4	RANBP3	Q15418	RPS6KA1	T75	S72L	72	Missense	distal	-3	no	1.543	2.031	EPSD	TCGA;ICGC;COSMIC	1.787	Gain
AGC_RSK_RSKp90_RPS6KA1_ST	Q9H6Z4	RANBP3	Q15418	RPS6KA1	S126	E122G	122	Missense	distal	-4	no	1.840	1.733	PhosphoSitePlus	TCGA;COSMIC	1.787	Loss
AGC_RSK_RSKp90_RPS6KA1_ST	Q9H6Z4	RANBP3	Q15418	RPS6KA1	S126	P131S	131	Missense	distal	5	no	1.840	1.837	PhosphoSitePlus	TCGA;COSMIC	1.787	Down-regulation
AGC_RSK_RSKp90_RPS6KA1_ST	Q9H6Z4	RANBP3	Q15418	RPS6KA1	T194	P190L	190	Missense	distal	-4	no	2.298	2.366	EPSD	TCGA;ICGC;COSMIC	1.787	Up-regulation
AGC_RSK_RSKp90_RPS6KA1_ST	Q9H6Z4	RANBP3	Q15418	RPS6KA1	T377	A375T	375	Missense	proximal	-2	no	2.051	2.118	EPSD	TCGA;COSMIC	1.787	Up-regulation
AGC_RSK_RSKp90_RPS6KA1_ST	Q9H6Z4	RANBP3	Q15418	RPS6KA1	T377	R382Q	382	Missense	distal	5	no	2.051	1.850	EPSD	TCGA;COSMIC	1.787	Down-regulation
AGC_RSK_RSKp90_RPS6KA1_ST	P30305	CDC25B	Q15418	RPS6KA1	S91	R92Q	92	Missense	proximal	1	no	2.641	2.659	EPSD	TCGA;COSMIC	1.787	Up-regulation
AGC_RSK_RSKp90_RPS6KA1_ST	P30305	CDC25B	Q15418	RPS6KA1	S91	S89Y	89	Missense	proximal	-2	no	2.641	2.654	EPSD	TCGA;COSMIC	1.787	Up-regulation
AGC_RSK_RSKp90_RPS6KA1_ST	P30305	CDC25B	Q15418	RPS6KA1	S91	E96K	96	Missense	distal	5	no	2.641	2.528	EPSD	TCGA;COSMIC	1.787	Down-regulation
AGC_RSK_RSKp90_RPS6KA1_ST	P30305	CDC25B	Q15418	RPS6KA1	S91	R84H	84	Missense	distal	-7	no	2.641	2.607	EPSD	TCGA;COSMIC	1.787	Down-regulation
AGC_RSK_RSKp90_RPS6KA1_ST	P30305	CDC25B	Q15418	RPS6KA1	S229	A225V	225	Missense	distal	-4	no	3.059	2.868	EPSD	TCGA;ICGC;COSMIC	1.787	Down-regulation
AGC_RSK_RSKp90_RPS6KA1_ST	P30305	CDC25B	Q15418	RPS6KA1	S229	Q226H	226	Missense	distal	-3	no	3.059	3.051	EPSD	TCGA;ICGC;COSMIC	1.787	Down-regulation
AGC_RSK_RSKp90_RPS6KA1_ST	P30305	CDC25B	Q15418	RPS6KA1	S313	R317Q	317	Missense	distal	4	no	2.414	2.419	EPSD	TCGA;COSMIC	1.787	Up-regulation
AGC_RSK_RSKp90_RPS6KA1_ST	P30307	CDC25C	Q15418	RPS6KA1	S38	D36Y	36	Missense	proximal	-2	no	3.201	3.196	EPSD	TCGA;ICGC	1.787	Down-regulation
AGC_RSK_RSKp90_RPS6KA1_ST	P30307	CDC25C	Q15418	RPS6KA1	S216	N222K	222	Missense	distal	6	no	2.845	2.656	EPSD	TCGA;ICGC;COSMIC	1.787	Down-regulation
AGC_RSK_RSKp90_RPS6KA1_ST	P30307	CDC25C	Q15418	RPS6KA1	S216	P215Q	215	Missense	proximal	-1	no	2.845	2.731	EPSD	TCGA;ICGC;COSMIC	1.787	Down-regulation
AGC_RSK_RSKp90_RPS6KA1_ST	P30307	CDC25C	Q15418	RPS6KA1	S216	R213H	213	Missense	distal	-3	no	2.845	2.427	EPSD	TCGA;ICGC;COSMIC	1.787	Down-regulation
AGC_RSK_RSKp90_RPS6KA1_ST	P30307	CDC25C	Q15418	RPS6KA1	S216	R213C	213	Missense	distal	-3	no	2.845	2.194	EPSD	TCGA;ICGC;COSMIC	1.787	Down-regulation
AGC_RSK_RSKp90_RPS6KA1_ST	P30307	CDC25C	Q15418	RPS6KA1	S216	S214F	214	Missense	proximal	-2	no	2.845	2.856	EPSD	TCGA;ICGC;COSMIC	1.787	Up-regulation
AGC_RSK_RSKp90_RPS6KA1_ST	P30307	CDC25C	Q15418	RPS6KA1	S216	L221S	221	Missense	distal	5	no	2.845	2.854	EPSD	TCGA;ICGC;COSMIC	1.787	Up-regulation
AGC_RSK_RSKp90_RPS6KA1_ST	P30307	CDC25C	Q15418	RPS6KA1	S216	P218S	218	Missense	proximal	2	no	2.845	2.667	EPSD	TCGA;ICGC	1.787	Down-regulation
AGC_RSK_RSKp90_RPS6KA1_ST	P30307	CDC25C	Q15418	RPS6KA1	T261	S263F	263	Missense	proximal	2	no	1.934	2.006	EPSD	TCGA;ICGC;COSMIC	1.787	Up-regulation
AGC_RSK_RSKp90_RPS6KA1_ST	Q8TB45	DEPTOR	Q15418	RPS6KA1	T259	M262I	262	Missense	distal	3	no	2.132	2.178	EPSD	TCGA;COSMIC	1.787	Up-regulation
AGC_RSK_RSKp90_RPS6KA1_ST	Q8TB45	DEPTOR	Q15418	RPS6KA1	T259	V264L	264	Missense	distal	5	no	2.132	1.991	EPSD	TCGA;COSMIC	1.787	Down-regulation
AGC_RSK_RSKp90_RPS6KA1_ST	Q8TB45	DEPTOR	Q15418	RPS6KA1	T259	S265N	265	Missense	distal	6	no	2.132	2.194	EPSD	TCGA;COSMIC	1.787	Up-regulation
AGC_RSK_RSKp90_RPS6KA1_ST	Q8TB45	DEPTOR	Q15418	RPS6KA1	S260	M262I	262	Missense	proximal	2	no	1.651	1.797	EPSD	TCGA;COSMIC	1.787	Gain
AGC_RSK_RSKp90_RPS6KA1_ST	P49815	TSC2	Q15418	RPS6KA1	S311	S311F	311	Missense	central	0	yes	1.873	0.000	EPSD	TCGA;ICGC;COSMIC	1.787	Loss
AGC_RSK_RSKp90_RPS6KA1_ST	P49815	TSC2	Q15418	RPS6KA1	S609	A607V	607	Missense	proximal	-2	no	1.958	2.016	EPSD	TCGA;ICGC	1.787	Up-regulation
AGC_RSK_RSKp90_RPS6KA1_ST	P49815	TSC2	Q15418	RPS6KA1	T927	R934S	934	Missense	distal	7	no	1.808	1.700	EPSD	TCGA;ICGC;COSMIC	1.787	Loss
AGC_RSK_RSKp90_RPS6KA1_ST	P49815	TSC2	Q15418	RPS6KA1	S999	D1004N	1004	Missense	distal	5	no	1.893	1.865	EPSD	TCGA;COSMIC	1.787	Down-regulation
AGC_RSK_RSKp90_RPS6KA1_ST	P49815	TSC2	Q15418	RPS6KA1	S999	G1001V	1001	Missense	proximal	2	no	1.893	1.850	EPSD	TCGA;COSMIC	1.787	Down-regulation
AGC_RSK_RSKp90_RPS6KA1_ST	P49815	TSC2	Q15418	RPS6KA1	S1097	P1098L	1098	Missense	proximal	1	no	2.532	2.580	EPSD	TCGA;COSMIC	1.787	Up-regulation
AGC_RSK_RSKp90_RPS6KA1_ST	P49815	TSC2	Q15418	RPS6KA1	S1097	G1091S	1091	Missense	distal	-6	no	2.532	1.864	EPSD	TCGA;COSMIC	1.787	Down-regulation
AGC_RSK_RSKp90_RPS6KA1_ST	P49815	TSC2	Q15418	RPS6KA1	S1337	E1343D	1343	Missense	distal	6	no	2.255	2.085	EPSD	TCGA	1.787	Down-regulation
AGC_RSK_RSKp90_RPS6KA1_ST	P49815	TSC2	Q15418	RPS6KA1	S1364	E1360K	1360	Missense	distal	-4	no	2.532	2.519	EPSD	TCGA	1.787	Down-regulation
AGC_RSK_RSKp90_RPS6KA1_ST	P49815	TSC2	Q15418	RPS6KA1	S1427	S1431L	1431	Missense	distal	4	no	2.187	2.238	EPSD	TCGA;COSMIC	1.787	Up-regulation
AGC_RSK_RSKp90_RPS6KA1_ST	P49815	TSC2	Q15418	RPS6KA1	S1466	S1466L	1466	Missense	central	0	yes	3.004	0.000	EPSD	TCGA	1.787	Loss
AGC_RSK_RSKp90_RPS6KA1_ST	P49815	TSC2	Q15418	RPS6KA1	S1761	A1759T	1759	Missense	proximal	-2	no	1.738	1.804	EPSD	TCGA;COSMIC	1.787	Gain
AGC_RSK_RSKp90_RPS6KA1_ST	O00418	EEF2K	Q15418	RPS6KA1	S18	H23Y	23	Missense	distal	5	no	1.602	1.803	EPSD	TCGA;ICGC;COSMIC	1.787	Gain
AGC_RSK_RSKp90_RPS6KA1_ST	O00418	EEF2K	Q15418	RPS6KA1	S71	E67K	67	Missense	distal	-4	no	1.969	1.956	EPSD	TCGA;ICGC;COSMIC	1.787	Down-regulation
AGC_RSK_RSKp90_RPS6KA1_ST	O00418	EEF2K	Q15418	RPS6KA1	S71	R68W	68	Missense	distal	-3	no	1.969	1.531	EPSD	TCGA	1.787	Loss
AGC_RSK_RSKp90_RPS6KA1_ST	O00418	EEF2K	Q15418	RPS6KA1	S71	S74C	74	Missense	distal	3	no	1.969	2.013	EPSD	TCGA;ICGC;COSMIC	1.787	Up-regulation
AGC_RSK_RSKp90_RPS6KA1_ST	O00418	EEF2K	Q15418	RPS6KA1	S241	N240S	240	Missense	proximal	-1	no	1.778	1.838	EPSD	TCGA;ICGC;COSMIC	1.787	Gain
AGC_RSK_RSKp90_RPS6KA1_ST	O00418	EEF2K	Q15418	RPS6KA1	T340	A346S	346	Missense	distal	6	no	1.985	2.069	EPSD	TCGA;ICGC;COSMIC	1.787	Up-regulation
AGC_RSK_RSKp90_RPS6KA1_ST	O00418	EEF2K	Q15418	RPS6KA1	T353	R351K	351	Missense	proximal	-2	no	1.733	1.828	EPSD	TCGA;ICGC;COSMIC	1.787	Gain
AGC_RSK_RSKp90_RPS6KA1_ST	O00418	EEF2K	Q15418	RPS6KA1	S359	S366F	366	Missense	distal	7	no	2.297	2.355	EPSD	TCGA;ICGC;COSMIC	1.787	Up-regulation
AGC_RSK_RSKp90_RPS6KA1_ST	O00418	EEF2K	Q15418	RPS6KA1	S359	S366C	366	Missense	distal	7	no	2.297	2.493	EPSD	TCGA;ICGC;COSMIC	1.787	Up-regulation
AGC_RSK_RSKp90_RPS6KA1_ST	O00418	EEF2K	Q15418	RPS6KA1	T364	S366F	366	Missense	proximal	2	no	2.078	2.150	EPSD	TCGA;ICGC;COSMIC	1.787	Up-regulation
AGC_RSK_RSKp90_RPS6KA1_ST	O00418	EEF2K	Q15418	RPS6KA1	T364	S366C	366	Missense	proximal	2	no	2.078	2.339	EPSD	TCGA;ICGC;COSMIC	1.787	Up-regulation
AGC_RSK_RSKp90_RPS6KA1_ST	O00418	EEF2K	Q15418	RPS6KA1	T364	P371S	371	Missense	distal	7	no	2.078	1.976	EPSD	TCGA;ICGC;COSMIC	1.787	Down-regulation
AGC_RSK_RSKp90_RPS6KA1_ST	O00418	EEF2K	Q15418	RPS6KA1	S377	P371S	371	Missense	distal	-6	no	2.448	2.108	EPSD	TCGA;ICGC;COSMIC	1.787	Down-regulation
AGC_RSK_RSKp90_RPS6KA1_ST	O00418	EEF2K	Q15418	RPS6KA1	S478	V483A	483	Missense	distal	5	no	1.938	1.854	EPSD	TCGA;ICGC;COSMIC	1.787	Down-regulation
AGC_RSK_RSKp90_RPS6KA1_ST	O00418	EEF2K	Q15418	RPS6KA1	S478	E484D	484	Missense	distal	6	no	1.938	1.768	EPSD	TCGA;ICGC;COSMIC	1.787	Loss
AGC_RSK_RSKp90_RPS6KA1_ST	O00418	EEF2K	Q15418	RPS6KA1	S478	E472G	472	Missense	distal	-6	no	1.938	2.426	EPSD	TCGA;ICGC;COSMIC	1.787	Up-regulation
AGC_RSK_RSKp90_RPS6KA1_ST	O00418	EEF2K	Q15418	RPS6KA1	S478	E472K	472	Missense	distal	-6	no	1.938	2.413	EPSD	TCGA;ICGC	1.787	Up-regulation
AGC_RSK_RSKp90_RPS6KA1_ST	P03372	ESR1	Q15418	RPS6KA1	S46	Y52H	52	Missense	distal	6	no	1.897	2.003	EPSD	TCGA;ICGC;COSMIC	1.787	Up-regulation
AGC_RSK_RSKp90_RPS6KA1_ST	P03372	ESR1	Q15418	RPS6KA1	S46	E41D	41	Missense	distal	-5	no	1.897	2.156	EPSD	TCGA;ICGC;COSMIC	1.787	Up-regulation
AGC_RSK_RSKp90_RPS6KA1_ST	P03372	ESR1	Q15418	RPS6KA1	S46	G40V	40	Missense	distal	-6	no	1.897	1.041	EPSD	TCGA;ICGC;COSMIC	1.787	Loss
AGC_RSK_RSKp90_RPS6KA1_ST	P03372	ESR1	Q15418	RPS6KA1	S47	Y52H	52	Missense	distal	5	no	2.612	2.410	EPSD	TCGA;ICGC;COSMIC	1.787	Down-regulation
AGC_RSK_RSKp90_RPS6KA1_ST	P03372	ESR1	Q15418	RPS6KA1	S47	E41D	41	Missense	distal	-6	no	2.612	2.546	EPSD	TCGA;ICGC;COSMIC	1.787	Down-regulation
AGC_RSK_RSKp90_RPS6KA1_ST	P03372	ESR1	Q15418	RPS6KA1	S47	G40V	40	Missense	distal	-7	no	2.612	2.621	EPSD	TCGA;ICGC;COSMIC	1.787	Up-regulation
AGC_RSK_RSKp90_RPS6KA1_ST	P03372	ESR1	Q15418	RPS6KA1	S329	P336T	336	Missense	distal	7	no	2.028	1.883	EPSD	TCGA;ICGC;COSMIC	1.787	Down-regulation
AGC_RSK_RSKp90_RPS6KA1_ST	P03372	ESR1	Q15418	RPS6KA1	S329	E330D	330	Missense	proximal	1	no	2.028	1.998	EPSD	TCGA;ICGC;COSMIC	1.787	Down-regulation
AGC_RSK_RSKp90_RPS6KA1_ST	P03372	ESR1	Q15418	RPS6KA1	T485	D484G	484	Missense	proximal	-1	no	1.859	1.977	EPSD	TCGA;ICGC;COSMIC	1.787	Up-regulation
AGC_RSK_RSKp90_RPS6KA1_ST	P03372	ESR1	Q15418	RPS6KA1	T485	H488Y	488	Missense	distal	3	no	1.859	1.802	EPSD	TCGA;ICGC;COSMIC	1.787	Down-regulation
AGC_RSK_RSKp90_RPS6KA1_ST	P62753	RPS6	Q15418	RPS6KA1	S82	R87K	87	Missense	distal	5	no	2.557	2.248	EPSD	TCGA;ICGC	1.787	Down-regulation
AGC_RSK_RSKp90_RPS6KA1_ST	P62753	RPS6	Q15418	RPS6KA1	S82	R88G	88	Missense	distal	6	no	2.557	2.587	EPSD	TCGA;ICGC	1.787	Up-regulation
AGC_RSK_RSKp90_RPS6KA1_ST	P62753	RPS6	Q15418	RPS6KA1	S247	Q248H	248	Missense	proximal	1	no	1.960	1.965	EPSD	TCGA;ICGC;COSMIC	1.787	Up-regulation
AGC_RSK_RSKp90_RPS6KA1_ST	O14757	CHEK1	Q15418	RPS6KA1	T330	G324C	324	Missense	distal	-6	no	2.261	1.831	EPSD	TCGA;ICGC;COSMIC	1.787	Down-regulation
AGC_RSK_RSKp90_RPS6KA1_ST	O14757	CHEK1	Q15418	RPS6KA1	T330	D336N	336	Missense	distal	6	no	2.261	2.373	EPSD	TCGA;ICGC;COSMIC	1.787	Up-regulation
AGC_RSK_RSKp90_RPS6KA1_ST	O14757	CHEK1	Q15418	RPS6KA1	T330	K337R	337	Missense	distal	7	no	2.261	2.410	EPSD	TCGA;ICGC;COSMIC	1.787	Up-regulation
AGC_RSK_RSKp90_RPS6KA1_ST	P21333	FLNA	Q15418	RPS6KA1	S72	T69M	69	Missense	distal	-3	no	2.202	2.440	EPSD	TCGA;ICGC;COSMIC	1.787	Up-regulation
AGC_RSK_RSKp90_RPS6KA1_ST	P21333	FLNA	Q15418	RPS6KA1	S72	A79V	79	Missense	distal	7	no	2.202	2.433	EPSD	TCGA;ICGC	1.787	Up-regulation
AGC_RSK_RSKp90_RPS6KA1_ST	P21333	FLNA	Q15418	RPS6KA1	S72	A65T	65	Missense	distal	-7	no	2.202	2.197	EPSD	TCGA;ICGC	1.787	Down-regulation
AGC_RSK_RSKp90_RPS6KA1_ST	P21333	FLNA	Q15418	RPS6KA1	S368	F370Y	370	Missense	proximal	2	no	3.245	3.211	EPSD	TCGA;ICGC;COSMIC	1.787	Down-regulation
AGC_RSK_RSKp90_RPS6KA1_ST	P21333	FLNA	Q15418	RPS6KA1	S368	E371D	371	Missense	distal	3	no	3.245	3.253	EPSD	TCGA;ICGC	1.787	Up-regulation
AGC_RSK_RSKp90_RPS6KA1_ST	P21333	FLNA	Q15418	RPS6KA1	S368	E371K	371	Missense	distal	3	no	3.245	3.310	EPSD	TCGA;ICGC	1.787	Up-regulation
AGC_RSK_RSKp90_RPS6KA1_ST	P21333	FLNA	Q15418	RPS6KA1	S368	A366T	366	Missense	proximal	-2	no	3.245	3.311	EPSD	TCGA;ICGC;COSMIC;CCLE	1.787	Up-regulation
AGC_RSK_RSKp90_RPS6KA1_ST	P21333	FLNA	Q15418	RPS6KA1	S368	V372A	372	Missense	distal	4	no	3.245	3.295	EPSD	TCGA;ICGC	1.787	Up-regulation
AGC_RSK_RSKp90_RPS6KA1_ST	P21333	FLNA	Q15418	RPS6KA1	T685	R678H	678	Missense	distal	-7	no	1.908	1.874	EPSD	TCGA;ICGC;COSMIC	1.787	Down-regulation
AGC_RSK_RSKp90_RPS6KA1_ST	P21333	FLNA	Q15418	RPS6KA1	T885	G881A	881	Missense	distal	-4	no	1.777	1.867	EPSD	TCGA;ICGC;COSMIC	1.787	Gain
AGC_RSK_RSKp90_RPS6KA1_ST	P21333	FLNA	Q15418	RPS6KA1	T885	P880T	880	Missense	distal	-5	no	1.777	1.842	EPSD	TCGA;ICGC;COSMIC	1.787	Gain
AGC_RSK_RSKp90_RPS6KA1_ST	P21333	FLNA	Q15418	RPS6KA1	T885	R884H	884	Missense	proximal	-1	no	1.777	1.923	EPSD	TCGA;ICGC;COSMIC	1.787	Gain
AGC_RSK_RSKp90_RPS6KA1_ST	P21333	FLNA	Q15418	RPS6KA1	T950	V947I	947	Missense	distal	-3	no	1.969	2.414	EPSD	TCGA;ICGC;COSMIC	1.787	Up-regulation
AGC_RSK_RSKp90_RPS6KA1_ST	P21333	FLNA	Q15418	RPS6KA1	T950	D954Y	954	Missense	distal	4	no	1.969	1.977	EPSD	TCGA;ICGC;COSMIC	1.787	Up-regulation
AGC_RSK_RSKp90_RPS6KA1_ST	P21333	FLNA	Q15418	RPS6KA1	T950	G946C	946	Missense	distal	-4	no	1.969	2.026	EPSD	TCGA;ICGC;COSMIC	1.787	Up-regulation
AGC_RSK_RSKp90_RPS6KA1_ST	P21333	FLNA	Q15418	RPS6KA1	T950	T950P	950	Missense	central	0	yes	1.969	0.000	EPSD	TCGA;ICGC;COSMIC	1.787	Loss
AGC_RSK_RSKp90_RPS6KA1_ST	P21333	FLNA	Q15418	RPS6KA1	S1161	A1160S	1160	Missense	proximal	-1	no	1.672	1.918	EPSD	TCGA;ICGC	1.787	Gain
AGC_RSK_RSKp90_RPS6KA1_ST	P21333	FLNA	Q15418	RPS6KA1	S1161	A1160T	1160	Missense	proximal	-1	no	1.672	1.857	EPSD	TCGA;ICGC;COSMIC;CCLE	1.787	Gain
AGC_RSK_RSKp90_RPS6KA1_ST	P21333	FLNA	Q15418	RPS6KA1	T1275	R1272C	1272	Missense	distal	-3	no	2.616	1.965	EPSD	TCGA;ICGC;COSMIC	1.787	Down-regulation
AGC_RSK_RSKp90_RPS6KA1_ST	P21333	FLNA	Q15418	RPS6KA1	T1275	Q1268H	1268	Missense	distal	-7	no	2.616	2.633	EPSD	TCGA;ICGC	1.787	Up-regulation
AGC_RSK_RSKp90_RPS6KA1_ST	P21333	FLNA	Q15418	RPS6KA1	T1275	A1282T	1282	Missense	distal	7	no	2.616	2.621	EPSD	TCGA;ICGC	1.787	Up-regulation
AGC_RSK_RSKp90_RPS6KA1_ST	P21333	FLNA	Q15418	RPS6KA1	T1275	R1272H	1272	Missense	distal	-3	no	2.616	2.198	EPSD	TCGA;ICGC;COSMIC	1.787	Down-regulation
AGC_RSK_RSKp90_RPS6KA1_ST	P21333	FLNA	Q15418	RPS6KA1	T1288	A1282T	1282	Missense	distal	-6	no	1.405	1.831	EPSD	TCGA;ICGC	1.787	Gain
AGC_RSK_RSKp90_RPS6KA1_ST	P21333	FLNA	Q15418	RPS6KA1	T1427	G1420A	1420	Missense	distal	-7	no	2.803	2.850	EPSD	TCGA;ICGC;COSMIC	1.787	Up-regulation
AGC_RSK_RSKp90_RPS6KA1_ST	P21333	FLNA	Q15418	RPS6KA1	T1558	G1554R	1554	Missense	distal	-4	no	2.077	2.198	EPSD	TCGA;ICGC;COSMIC	1.787	Up-regulation
AGC_RSK_RSKp90_RPS6KA1_ST	P21333	FLNA	Q15418	RPS6KA1	T1558	V1560L	1560	Missense	proximal	2	no	2.077	1.958	EPSD	TCGA;ICGC;COSMIC	1.787	Down-regulation
AGC_RSK_RSKp90_RPS6KA1_ST	P21333	FLNA	Q15418	RPS6KA1	S1630	R1635C	1635	Missense	distal	5	no	1.891	1.690	EPSD	TCGA;ICGC;COSMIC	1.787	Loss
AGC_RSK_RSKp90_RPS6KA1_ST	P21333	FLNA	Q15418	RPS6KA1	S1630	P1628L	1628	Missense	proximal	-2	no	1.891	1.884	EPSD	TCGA;ICGC;COSMIC	1.787	Down-regulation
AGC_RSK_RSKp90_RPS6KA1_ST	P21333	FLNA	Q15418	RPS6KA1	S1630	P1631S	1631	Missense	proximal	1	no	1.891	1.845	EPSD	TCGA;ICGC;COSMIC	1.787	Down-regulation
AGC_RSK_RSKp90_RPS6KA1_ST	P21333	FLNA	Q15418	RPS6KA1	S1630	V1637M	1637	Missense	distal	7	no	1.891	1.708	EPSD	TCGA;ICGC;COSMIC;CCLE	1.787	Loss
AGC_RSK_RSKp90_RPS6KA1_ST	P21333	FLNA	Q15418	RPS6KA1	S1630	R1633H	1633	Missense	distal	3	no	1.891	2.004	EPSD	TCGA;ICGC;COSMIC;GDSC;CCLE	1.787	Up-regulation
AGC_RSK_RSKp90_RPS6KA1_ST	P21333	FLNA	Q15418	RPS6KA1	S1812	A1816T	1816	Missense	distal	4	no	2.967	2.983	EPSD	TCGA	1.787	Up-regulation
AGC_RSK_RSKp90_RPS6KA1_ST	P21333	FLNA	Q15418	RPS6KA1	S1812	R1809W	1809	Missense	distal	-3	no	2.967	2.529	EPSD	TCGA	1.787	Down-regulation
AGC_RSK_RSKp90_RPS6KA1_ST	P21333	FLNA	Q15418	RPS6KA1	S1812	G1813C	1813	Missense	proximal	1	no	2.967	3.055	EPSD	TCGA;COSMIC	1.787	Up-regulation
AGC_RSK_RSKp90_RPS6KA1_ST	P21333	FLNA	Q15418	RPS6KA1	S1967	S1961P	1961	Missense	distal	-6	no	1.510	1.851	EPSD	TCGA;COSMIC	1.787	Gain
AGC_RSK_RSKp90_RPS6KA1_ST	P21333	FLNA	Q15418	RPS6KA1	S2158	S2152L	2152	Missense	distal	-6	no	2.121	2.620	EPSD	TCGA;COSMIC	1.787	Up-regulation
AGC_RSK_RSKp90_RPS6KA1_ST	P21333	FLNA	Q15418	RPS6KA1	T2209	Y2216F	2216	Missense	distal	7	no	2.209	2.147	EPSD	TCGA;COSMIC	1.787	Down-regulation
AGC_RSK_RSKp90_RPS6KA1_ST	P21333	FLNA	Q15418	RPS6KA1	T2209	P2204L	2204	Missense	distal	-5	no	2.209	2.213	EPSD	TCGA;COSMIC	1.787	Up-regulation
AGC_RSK_RSKp90_RPS6KA1_ST	P21333	FLNA	Q15418	RPS6KA1	T2209	V2214M	2214	Missense	distal	5	no	2.209	2.099	EPSD	TCGA;COSMIC	1.787	Down-regulation
AGC_RSK_RSKp90_RPS6KA1_ST	P21333	FLNA	Q15418	RPS6KA1	T2229	V2230L	2230	Missense	proximal	1	no	1.730	1.811	EPSD	TCGA;COSMIC	1.787	Gain
AGC_RSK_RSKp90_RPS6KA1_ST	P21333	FLNA	Q15418	RPS6KA1	T2229	V2230M	2230	Missense	proximal	1	no	1.730	1.790	EPSD	TCGA;COSMIC;GDSC;CCLE	1.787	Gain
AGC_RSK_RSKp90_RPS6KA1_ST	P21333	FLNA	Q15418	RPS6KA1	S2260	E2258K	2258	Missense	proximal	-2	no	2.156	2.190	EPSD	TCGA;COSMIC	1.787	Up-regulation
AGC_RSK_RSKp90_RPS6KA1_ST	P21333	FLNA	Q15418	RPS6KA1	S2414	P2415S	2415	Missense	proximal	1	no	2.574	2.528	EPSD	TCGA	1.787	Down-regulation
AGC_RSK_RSKp90_RPS6KA1_ST	P21333	FLNA	Q15418	RPS6KA1	S2523	G2518C	2518	Missense	distal	-5	no	2.291	2.374	EPSD	TCGA;COSMIC	1.787	Up-regulation
AGC_RSK_RSKp90_RPS6KA1_ST	P21333	FLNA	Q15418	RPS6KA1	S2523	S2526I	2526	Missense	distal	3	no	2.291	2.350	EPSD	TCGA	1.787	Up-regulation
AGC_RSK_RSKp90_RPS6KA1_ST	P21333	FLNA	Q15418	RPS6KA1	S2611	R2612W	2612	Missense	proximal	1	no	2.499	2.521	EPSD	TCGA;GDSC	1.787	Up-regulation
AGC_RSK_RSKp90_RPS6KA1_ST	P21333	FLNA	Q15418	RPS6KA1	S2611	V2609M	2609	Missense	proximal	-2	no	2.499	2.468	EPSD	TCGA;COSMIC;GDSC;CCLE	1.787	Down-regulation
AGC_RSK_RSKp90_RPS6KA1_ST	P21333	FLNA	Q15418	RPS6KA1	S2611	S2617P	2617	Missense	distal	6	no	2.499	2.406	EPSD	TCGA;COSMIC	1.787	Down-regulation
AGC_RSK_RSKp90_RPS6KA1_ST	P21333	FLNA	Q15418	RPS6KA1	T2627	D2634N	2634	Missense	distal	7	no	2.122	2.134	EPSD	TCGA;COSMIC	1.787	Up-regulation
AGC_RSK_RSKp90_RPS6KA1_ST	P21333	FLNA	Q15418	RPS6KA1	T2627	W2632R	2632	Missense	distal	5	no	2.122	2.308	EPSD	TCGA;COSMIC	1.787	Up-regulation
AGC_RSK_RSKp90_RPS6KA1_ST	P21333	FLNA	Q15418	RPS6KA1	T2627	V2630D	2630	Missense	distal	3	no	2.122	2.118	EPSD	TCGA;COSMIC	1.787	Down-regulation
AGC_RSK_RSKp90_RPS6KA1_ST	P78371	CCT2	Q15418	RPS6KA1	S28	A34T	34	Missense	distal	6	no	2.187	2.124	EPSD	TCGA;ICGC;COSMIC	1.787	Down-regulation
AGC_RSK_RSKp90_RPS6KA1_ST	P78371	CCT2	Q15418	RPS6KA1	S60	D58N	58	Missense	proximal	-2	no	2.289	2.313	EPSD	TCGA;ICGC;COSMIC	1.787	Up-regulation
AGC_RSK_RSKp90_RPS6KA1_ST	P78371	CCT2	Q15418	RPS6KA1	S115	I121S	121	Missense	distal	6	no	1.743	1.796	EPSD	TCGA;ICGC;COSMIC	1.787	Gain
AGC_RSK_RSKp90_RPS6KA1_ST	Q53EL6	PDCD4	Q15418	RPS6KA1	S71	S67L	67	Missense	distal	-4	no	1.924	2.183	EPSD	TCGA;ICGC;COSMIC	1.787	Up-regulation
AGC_RSK_RSKp90_RPS6KA1_ST	Q53EL6	PDCD4	Q15418	RPS6KA1	S71	K65T	65	Missense	distal	-6	no	1.924	1.966	EPSD	TCGA;ICGC	1.787	Up-regulation
AGC_RSK_RSKp90_RPS6KA1_ST	Q53EL6	PDCD4	Q15418	RPS6KA1	S71	R69Q	69	Missense	proximal	-2	no	1.924	1.998	EPSD	TCGA;ICGC;COSMIC	1.787	Up-regulation
AGC_RSK_RSKp90_RPS6KA1_ST	Q53EL6	PDCD4	Q15418	RPS6KA1	S94	L99M	99	Missense	distal	5	no	3.119	3.150	EPSD	TCGA;ICGC	1.787	Up-regulation
AGC_RSK_RSKp90_RPS6KA1_ST	Q53EL6	PDCD4	Q15418	RPS6KA1	S94	T93A	93	Missense	proximal	-1	no	3.119	2.934	EPSD	TCGA;ICGC	1.787	Down-regulation
AGC_RSK_RSKp90_RPS6KA1_ST	Q53EL6	PDCD4	Q15418	RPS6KA1	S313	G308A	308	Missense	distal	-5	no	2.077	1.918	EPSD	TCGA;ICGC;COSMIC	1.787	Down-regulation
AGC_RSK_RSKp90_RPS6KA1_ST	Q53EL6	PDCD4	Q15418	RPS6KA1	S313	R310H	310	Missense	distal	-3	no	2.077	1.658	EPSD	TCGA;ICGC;COSMIC	1.787	Loss
AGC_RSK_RSKp90_RPS6KA1_ST	Q07889	SOS1	Q15418	RPS6KA1	S403	A404T	404	Missense	proximal	1	no	2.640	2.565	EPSD	TCGA;ICGC;COSMIC	1.787	Down-regulation
AGC_RSK_RSKp90_RPS6KA1_ST	Q07889	SOS1	Q15418	RPS6KA1	S1082	S1082Y	1082	Missense	central	0	yes	2.072	0.000	EPSD	TCGA;ICGC;COSMIC	1.787	Loss
AGC_RSK_RSKp90_RPS6KA1_ST	Q07889	SOS1	Q15418	RPS6KA1	S1134	S1134C	1134	Missense	central	0	yes	2.053	0.000	PhosphoSitePlus;EPSD	TCGA;ICGC;COSMIC	1.787	Loss
AGC_RSK_RSKp90_RPS6KA1_ST	Q07889	SOS1	Q15418	RPS6KA1	S1139	D1145N	1145	Missense	distal	6	no	2.117	2.228	EPSD	TCGA;ICGC;COSMIC	1.787	Up-regulation
AGC_RSK_RSKp90_RPS6KA1_ST	Q07889	SOS1	Q15418	RPS6KA1	S1139	S1134C	1134	Missense	distal	-5	no	2.117	2.380	EPSD	TCGA;ICGC;COSMIC	1.787	Up-regulation
AGC_RSK_RSKp90_RPS6KA1_ST	Q07889	SOS1	Q15418	RPS6KA1	S1166	S1173P	1173	Missense	distal	7	no	1.813	1.915	EPSD	TCGA;ICGC;COSMIC	1.787	Up-regulation
AGC_RSK_RSKp90_RPS6KA1_ST	Q07889	SOS1	Q15418	RPS6KA1	T1269	P1266L	1266	Missense	distal	-3	no	1.424	2.009	EPSD	TCGA;COSMIC	1.787	Gain
AGC_RSK_RSKp90_RPS6KA1_ST	Q07889	SOS1	Q15418	RPS6KA1	T1279	H1285Q	1285	Missense	distal	6	no	2.069	1.996	EPSD	TCGA;COSMIC	1.787	Down-regulation
AGC_RSK_RSKp90_RPS6KA1_ST	P13796	LCP1	Q15418	RPS6KA1	T89	S83G	83	Missense	distal	-6	no	1.653	2.321	EPSD	TCGA;ICGC;COSMIC	1.787	Gain
AGC_RSK_RSKp90_RPS6KA1_ST	P13796	LCP1	Q15418	RPS6KA1	S110	I103F	103	Missense	distal	-7	no	1.876	1.898	EPSD	TCGA;ICGC;COSMIC	1.787	Up-regulation
AGC_RSK_RSKp90_RPS6KA1_ST	P13796	LCP1	Q15418	RPS6KA1	S110	G104D	104	Missense	distal	-6	no	1.876	1.322	EPSD	TCGA;ICGC;COSMIC	1.787	Loss
AGC_RSK_RSKp90_RPS6KA1_ST	P13796	LCP1	Q15418	RPS6KA1	S110	V112G	112	Missense	proximal	2	no	1.876	1.918	EPSD	TCGA;ICGC;COSMIC	1.787	Up-regulation
AGC_RSK_RSKp90_RPS6KA1_ST	P13796	LCP1	Q15418	RPS6KA1	S111	G104D	104	Missense	distal	-7	no	2.386	2.440	EPSD	TCGA;ICGC;COSMIC	1.787	Up-regulation
AGC_RSK_RSKp90_RPS6KA1_ST	P13796	LCP1	Q15418	RPS6KA1	S111	V112G	112	Missense	proximal	1	no	2.386	2.317	EPSD	TCGA;ICGC;COSMIC	1.787	Down-regulation
AGC_RSK_RSKp90_RPS6KA1_ST	P13796	LCP1	Q15418	RPS6KA1	S474	S474F	474	Missense	central	0	yes	2.365	0.000	EPSD	TCGA;ICGC;COSMIC	1.787	Loss
AGC_RSK_RSKp90_RPS6KA1_ST	P13796	LCP1	Q15418	RPS6KA1	S474	G479C	479	Missense	distal	5	no	2.365	2.602	EPSD	TCGA;ICGC;COSMIC	1.787	Up-regulation
AGC_RSK_RSKp90_RPS6KA1_ST	P13796	LCP1	Q15418	RPS6KA1	S474	G467V	467	Missense	distal	-7	no	2.365	2.374	EPSD	TCGA;ICGC;COSMIC	1.787	Up-regulation
AGC_RSK_RSKp90_RPS6KA1_ST	P13796	LCP1	Q15418	RPS6KA1	S474	G467W	467	Missense	distal	-7	no	2.365	2.367	EPSD	TCGA;ICGC	1.787	Up-regulation
AGC_RSK_RSKp90_RPS6KA1_ST	P13796	LCP1	Q15418	RPS6KA1	S474	A471V	471	Missense	distal	-3	no	2.365	1.799	EPSD	TCGA	1.787	Down-regulation
AGC_RSK_RSKp90_RPS6KA1_ST	P13796	LCP1	Q15418	RPS6KA1	S537	P544L	544	Missense	distal	7	no	1.795	1.701	EPSD	TCGA;COSMIC	1.787	Loss
AGC_RSK_RSKp90_RPS6KA1_ST	O14727	APAF1	Q15418	RPS6KA1	S238	S238F	238	Missense	central	0	yes	1.795	0.000	EPSD	TCGA;ICGC;COSMIC	1.787	Loss
AGC_RSK_RSKp90_RPS6KA1_ST	O14727	APAF1	Q15418	RPS6KA1	S238	D244H	244	Missense	distal	6	no	1.795	1.836	EPSD	TCGA;ICGC;COSMIC	1.787	Up-regulation
AGC_RSK_RSKp90_RPS6KA1_ST	O14727	APAF1	Q15418	RPS6KA1	S238	R233C	233	Missense	distal	-5	no	1.795	2.082	EPSD	TCGA;ICGC;GDSC;CCLE	1.787	Up-regulation
AGC_RSK_RSKp90_RPS6KA1_ST	O14727	APAF1	Q15418	RPS6KA1	S268	S272L	272	Missense	distal	4	no	2.874	2.924	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	1.787	Up-regulation
AGC_RSK_RSKp90_RPS6KA1_ST	O14727	APAF1	Q15418	RPS6KA1	S268	D266Y	266	Missense	proximal	-2	no	2.874	2.869	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	1.787	Down-regulation
AGC_RSK_RSKp90_RPS6KA1_ST	O14727	APAF1	Q15418	RPS6KA1	S432	R434H	434	Missense	proximal	2	no	2.396	2.228	EPSD	TCGA;ICGC;COSMIC;GDSC;CCLE	1.787	Down-regulation
AGC_RSK_RSKp90_RPS6KA1_ST	P53355	DAPK1	Q15418	RPS6KA1	S57	S51F	51	Missense	distal	-6	no	1.690	1.819	EPSD	TCGA	1.787	Gain
AGC_RSK_RSKp90_RPS6KA1_ST	P53355	DAPK1	Q15418	RPS6KA1	S326	M328V	328	Missense	proximal	2	no	2.159	2.388	EPSD	TCGA;ICGC;COSMIC	1.787	Up-regulation
AGC_RSK_RSKp90_RPS6KA1_ST	P53355	DAPK1	Q15418	RPS6KA1	S696	G697E	697	Missense	proximal	1	no	1.724	1.857	EPSD	TCGA;ICGC;COSMIC;GDSC;CCLE	1.787	Gain
AGC_RSK_RSKp90_RPS6KA1_ST	P53355	DAPK1	Q15418	RPS6KA1	S696	H695Y	695	Missense	proximal	-1	no	1.724	1.802	EPSD	TCGA;ICGC;COSMIC	1.787	Gain
AGC_RSK_RSKp90_RPS6KA1_ST	P53355	DAPK1	Q15418	RPS6KA1	S714	P721S	721	Missense	distal	7	no	2.022	1.920	EPSD	TCGA;ICGC;COSMIC	1.787	Down-regulation
AGC_RSK_RSKp90_RPS6KA1_ST	P53355	DAPK1	Q15418	RPS6KA1	S714	R719C	719	Missense	distal	5	no	2.022	1.822	EPSD	TCGA;ICGC;GDSC;CCLE	1.787	Down-regulation
AGC_RSK_RSKp90_RPS6KA1_ST	P53355	DAPK1	Q15418	RPS6KA1	S1115	R1114H	1114	Missense	proximal	-1	no	2.472	2.618	EPSD	TCGA;ICGC;COSMIC;CCLE	1.787	Up-regulation
AGC_RSK_RSKp90_RPS6KA1_ST	P53355	DAPK1	Q15418	RPS6KA1	S1115	D1118N	1118	Missense	distal	3	no	2.472	2.407	EPSD	TCGA;ICGC;COSMIC	1.787	Down-regulation
AGC_RSK_RSKp90_RPS6KA1_ST	Q9UBP6	METTL1	Q15418	RPS6KA1	S177	I176M	176	Missense	proximal	-1	no	2.614	2.822	EPSD	TCGA;ICGC;COSMIC	1.787	Up-regulation
AGC_RSK_RSKp90_RPS6KA1_ST	Q92882	OSTF1	Q15418	RPS6KA1	T195	R199Q	199	Missense	distal	4	no	1.937	1.942	EPSD	TCGA;ICGC;COSMIC;GDSC;CCLE	1.787	Up-regulation
AGC_RSK_RSKp90_RPS6KA1_ST	P30304	CDC25A	Q15418	RPS6KA1	S82	D87Y	87	Missense	distal	5	no	1.697	1.823	EPSD	TCGA;ICGC;COSMIC	1.787	Gain
AGC_RSK_RSKp90_RPS6KA1_ST	P30304	CDC25A	Q15418	RPS6KA1	S107	L113F	113	Missense	distal	6	no	1.987	1.995	EPSD	TCGA;ICGC;COSMIC	1.787	Up-regulation
AGC_RSK_RSKp90_RPS6KA1_ST	P30304	CDC25A	Q15418	RPS6KA1	S279	P284T	284	Missense	distal	5	no	1.935	1.930	EPSD	TCGA;ICGC;COSMIC	1.787	Down-regulation
AGC_RSK_RSKp90_RPS6KA1_ST	P30304	CDC25A	Q15418	RPS6KA1	S279	R275K	275	Missense	distal	-4	no	1.935	1.908	EPSD	TCGA;ICGC	1.787	Down-regulation
AGC_RSK_RSKp90_RPS6KA1_ST	P30304	CDC25A	Q15418	RPS6KA1	S320	S317F	317	Missense	distal	-3	no	1.986	1.992	EPSD	TCGA;ICGC;COSMIC	1.787	Up-regulation
AGC_RSK_RSKp90_RPS6KA1_ST	P60983	GMFB	Q15418	RPS6KA1	T27	A30T	30	Missense	distal	3	no	2.127	2.205	PhosphoSitePlus	TCGA;ICGC	1.787	Up-regulation
AGC_RSK_RSKp90_RPS6KA1_ST	P60983	GMFB	Q15418	RPS6KA1	S72	R67C	67	Missense	distal	-5	no	2.492	2.779	EPSD	TCGA;ICGC;COSMIC	1.787	Up-regulation
AGC_RSK_RSKp90_RPS6KA1_ST	P60983	GMFB	Q15418	RPS6KA1	S72	R67H	67	Missense	distal	-5	no	2.492	2.581	EPSD	TCGA;ICGC	1.787	Up-regulation
AGC_RSK_RSKp90_RPS6KA1_ST	P49427	CDC34	Q15418	RPS6KA1	T186	V192M	192	Missense	distal	6	no	2.010	2.125	EPSD	TCGA;ICGC;COSMIC	1.787	Up-regulation
AGC_RSK_RSKp90_RPS6KA1_ST	P49427	CDC34	Q15418	RPS6KA1	T186	T186M	186	Missense	central	0	yes	2.010	0.000	EPSD	TCGA;ICGC;COSMIC	1.787	Loss
AGC_RSK_RSKp90_RPS6KA1_ST	P29317	EPHA2	Q15418	RPS6KA1	S570	R568H	568	Missense	proximal	-2	no	2.741	2.829	EPSD	TCGA;ICGC;COSMIC	1.787	Up-regulation
AGC_RSK_RSKp90_RPS6KA1_ST	P29317	EPHA2	Q15418	RPS6KA1	S749	R743H	743	Missense	distal	-6	no	1.039	1.841	EPSD	TCGA;ICGC;COSMIC	1.787	Gain
AGC_RSK_RSKp90_RPS6KA1_ST	P29317	EPHA2	Q15418	RPS6KA1	T773	P768L	768	Missense	distal	-5	no	2.288	2.292	EPSD	TCGA;ICGC;COSMIC	1.787	Up-regulation
AGC_RSK_RSKp90_RPS6KA1_ST	P29317	EPHA2	Q15418	RPS6KA1	T773	E769K	769	Missense	distal	-4	no	2.288	2.275	EPSD	TCGA;ICGC	1.787	Down-regulation
AGC_RSK_RSKp90_RPS6KA1_ST	P29317	EPHA2	Q15418	RPS6KA1	S790	P786L	786	Missense	distal	-4	no	1.825	1.893	EPSD	TCGA;ICGC;COSMIC	1.787	Up-regulation
AGC_RSK_RSKp90_RPS6KA1_ST	P29317	EPHA2	Q15418	RPS6KA1	S790	S790F	790	Missense	central	0	yes	1.825	0.000	EPSD	TCGA;ICGC;COSMIC	1.787	Loss
AGC_RSK_RSKp90_RPS6KA1_ST	P29317	EPHA2	Q15418	RPS6KA1	S790	E787K	787	Missense	distal	-3	no	1.825	1.781	EPSD	TCGA;ICGC;COSMIC	1.787	Loss
AGC_RSK_RSKp90_RPS6KA1_ST	P29317	EPHA2	Q15418	RPS6KA1	S790	R792W	792	Missense	proximal	2	no	1.825	1.765	EPSD	TCGA;ICGC;COSMIC;GDSC;CCLE	1.787	Loss
AGC_RSK_RSKp90_RPS6KA1_ST	P29317	EPHA2	Q15418	RPS6KA1	S790	E787D	787	Missense	distal	-3	no	1.825	1.744	EPSD	TCGA;ICGC	1.787	Loss
AGC_RSK_RSKp90_RPS6KA1_ST	P29317	EPHA2	Q15418	RPS6KA1	S869	F864L	864	Missense	distal	-5	no	3.076	3.088	EPSD	TCGA	1.787	Up-regulation
AGC_RSK_RSKp90_RPS6KA1_ST	P29317	EPHA2	Q15418	RPS6KA1	S869	P862L	862	Missense	distal	-7	no	3.076	3.064	EPSD	TCGA;ICGC;COSMIC	1.787	Down-regulation
AGC_RSK_RSKp90_RPS6KA1_ST	P29317	EPHA2	Q15418	RPS6KA1	S869	P862S	862	Missense	distal	-7	no	3.076	3.084	EPSD	TCGA;ICGC;COSMIC	1.787	Up-regulation
AGC_RSK_RSKp90_RPS6KA1_ST	P29317	EPHA2	Q15418	RPS6KA1	S869	V868I	868	Missense	proximal	-1	no	3.076	2.807	EPSD	TCGA;ICGC;COSMIC	1.787	Down-regulation
AGC_RSK_RSKp90_RPS6KA1_ST	P29317	EPHA2	Q15418	RPS6KA1	S901	R907S	907	Missense	distal	6	no	1.961	1.990	EPSD	TCGA;ICGC;COSMIC	1.787	Up-regulation
AGC_RSK_RSKp90_RPS6KA1_ST	P29317	EPHA2	Q15418	RPS6KA1	S901	S899G	899	Missense	proximal	-2	no	1.961	2.026	EPSD	TCGA;ICGC;COSMIC	1.787	Up-regulation
AGC_RSK_RSKp90_RPS6KA1_ST	P23588	EIF4B	Q15418	RPS6KA1	S183	R190P	190	Missense	distal	7	no	2.232	2.227	EPSD	TCGA;COSMIC	1.787	Down-regulation
AGC_RSK_RSKp90_RPS6KA1_ST	P23588	EIF4B	Q15418	RPS6KA1	S183	R182H	182	Missense	proximal	-1	no	2.232	2.379	EPSD	TCGA;COSMIC	1.787	Up-regulation
AGC_RSK_RSKp90_RPS6KA1_ST	P23588	EIF4B	Q15418	RPS6KA1	S283	G284E	284	Missense	proximal	1	no	1.658	1.791	EPSD	TCGA	1.787	Gain
AGC_RSK_RSKp90_RPS6KA1_ST	P23588	EIF4B	Q15418	RPS6KA1	S406	R401W	401	Missense	distal	-5	no	1.692	1.834	EPSD	TCGA;COSMIC	1.787	Gain
AGC_RSK_RSKp90_RPS6KA1_ST	P23588	EIF4B	Q15418	RPS6KA1	S434	A437V	437	Missense	distal	3	no	1.857	1.861	EPSD	TCGA;COSMIC	1.787	Up-regulation
AGC_RSK_RSKp90_RPS6KA1_ST	P23588	EIF4B	Q15418	RPS6KA1	S434	R438Q	438	Missense	distal	4	no	1.857	1.862	EPSD	TCGA;COSMIC	1.787	Up-regulation
AGC_RSK_RSKp90_RPS6KA1_ST	P23588	EIF4B	Q15418	RPS6KA1	S495	E501Q	501	Missense	distal	6	no	1.825	1.623	EPSD	TCGA;COSMIC	1.787	Loss
AGC_RSK_RSKp90_RPS6KA1_ST	P23588	EIF4B	Q15418	RPS6KA1	S495	Q496E	496	Missense	proximal	1	no	1.825	1.812	EPSD	TCGA;COSMIC	1.787	Down-regulation
AGC_RSK_RSKp90_RPS6KA1_ST	P16144	ITGB4	Q15418	RPS6KA1	T168	F171S	171	Missense	distal	3	no	1.859	1.800	EPSD	TCGA;ICGC;COSMIC	1.787	Down-regulation
AGC_RSK_RSKp90_RPS6KA1_ST	P16144	ITGB4	Q15418	RPS6KA1	T1098	D1104N	1104	Missense	distal	6	no	1.684	1.795	EPSD	TCGA;ICGC;COSMIC	1.787	Gain
AGC_RSK_RSKp90_RPS6KA1_ST	P16144	ITGB4	Q15418	RPS6KA1	S1111	M1116K	1116	Missense	distal	5	no	2.523	2.399	EPSD	TCGA;ICGC;COSMIC	1.787	Down-regulation
AGC_RSK_RSKp90_RPS6KA1_ST	P16144	ITGB4	Q15418	RPS6KA1	S1111	D1104N	1104	Missense	distal	-7	no	2.523	2.506	EPSD	TCGA;ICGC;COSMIC	1.787	Down-regulation
AGC_RSK_RSKp90_RPS6KA1_ST	P16144	ITGB4	Q15418	RPS6KA1	S1111	P1105S	1105	Missense	distal	-6	no	2.523	2.182	EPSD	TCGA;ICGC;COSMIC	1.787	Down-regulation
AGC_RSK_RSKp90_RPS6KA1_ST	P16144	ITGB4	Q15418	RPS6KA1	S1118	M1116K	1116	Missense	proximal	-2	no	2.522	2.549	EPSD	TCGA;ICGC;COSMIC	1.787	Up-regulation
AGC_RSK_RSKp90_RPS6KA1_ST	P16144	ITGB4	Q15418	RPS6KA1	S1119	M1116K	1116	Missense	distal	-3	no	3.006	2.802	EPSD	TCGA;ICGC;COSMIC	1.787	Down-regulation
AGC_RSK_RSKp90_RPS6KA1_ST	P16144	ITGB4	Q15418	RPS6KA1	T1455	M1461T	1461	Missense	distal	6	no	1.912	1.808	EPSD	TCGA;COSMIC	1.787	Down-regulation
AGC_RSK_RSKp90_RPS6KA1_ST	P16144	ITGB4	Q15418	RPS6KA1	S1501	S1498L	1498	Missense	distal	-3	no	1.770	2.257	EPSD	TCGA;COSMIC	1.787	Gain
AGC_RSK_RSKp90_RPS6KA1_ST	Q9HC62	SENP2	Q15418	RPS6KA1	S38	L36V	36	Missense	proximal	-2	no	1.771	1.800	EPSD	TCGA;COSMIC	1.787	Gain
AGC_RSK_RSKp90_RPS6KA1_ST	Q9HC62	SENP2	Q15418	RPS6KA1	T39	L36V	36	Missense	distal	-3	no	2.466	1.811	EPSD	TCGA;COSMIC	1.787	Down-regulation
AGC_RSK_RSKp90_RPS6KA1_ST	Q9HC62	SENP2	Q15418	RPS6KA1	T39	D33G	33	Missense	distal	-6	no	2.466	3.020	EPSD	TCGA;ICGC;COSMIC	1.787	Up-regulation
AGC_RSK_RSKp90_RPS6KA1_ST	Q9HC62	SENP2	Q15418	RPS6KA1	S168	R166H	166	Missense	proximal	-2	no	2.257	2.344	EPSD	TCGA;ICGC;COSMIC	1.787	Up-regulation
AGC_RSK_RSKp90_RPS6KA1_ST	Q9HC62	SENP2	Q15418	RPS6KA1	S226	R222Q	222	Missense	distal	-4	no	2.417	2.321	EPSD	TCGA;COSMIC	1.787	Down-regulation
AGC_RSK_RSKp90_RPS6KA1_ST	Q9HC62	SENP2	Q15418	RPS6KA1	S231	P234H	234	Missense	distal	3	no	2.091	2.095	EPSD	TCGA	1.787	Up-regulation
AGC_RSK_RSKp90_RPS6KA1_ST	Q9HC62	SENP2	Q15418	RPS6KA1	S284	R279K	279	Missense	distal	-5	no	1.622	1.800	EPSD	TCGA;COSMIC	1.787	Gain
AGC_RSK_RSKp90_RPS6KA1_ST	Q9HC62	SENP2	Q15418	RPS6KA1	S287	C283Y	283	Missense	distal	-4	no	1.847	1.864	EPSD	TCGA	1.787	Up-regulation
AGC_RSK_RSKp90_RPS6KA1_ST	Q9HC62	SENP2	Q15418	RPS6KA1	T348	I345V	345	Missense	distal	-3	no	2.991	2.546	EPSD	TCGA;COSMIC	1.787	Down-regulation
AGC_RSK_RSKp90_RPS6KA1_ST	Q9HC62	SENP2	Q15418	RPS6KA1	T348	K351N	351	Missense	distal	3	no	2.991	2.870	EPSD	TCGA;COSMIC	1.787	Down-regulation
AGC_RSK_RSKp90_RPS6KA1_ST	Q9HC62	SENP2	Q15418	RPS6KA1	T369	D364N	364	Missense	distal	-5	no	2.495	2.518	PhosphoSitePlus	TCGA;ICGC;COSMIC	1.787	Up-regulation
AGC_RSK_RSKp90_RPS6KA1_ST	Q9HC62	SENP2	Q15418	RPS6KA1	T369	L365F	365	Missense	distal	-4	no	2.495	2.401	PhosphoSitePlus	TCGA;ICGC;COSMIC	1.787	Down-regulation
AGC_RSK_RSKp90_RPS6KA1_ST	Q9HC62	SENP2	Q15418	RPS6KA1	T369	D363G	363	Missense	distal	-6	no	2.495	3.048	PhosphoSitePlus	TCGA;COSMIC	1.787	Up-regulation
AGC_RSK_RSKp90_RPS6KA1_ST	P01100	FOS	Q15418	RPS6KA1	S122	A120V	120	Missense	proximal	-2	no	1.778	1.836	EPSD	TCGA;ICGC;COSMIC	1.787	Gain
AGC_RSK_RSKp90_RPS6KA1_ST	P01100	FOS	Q15418	RPS6KA1	S281	P275Q	275	Missense	distal	-6	no	1.813	1.619	EPSD	TCGA;COSMIC	1.787	Loss
AGC_RSK_RSKp90_RPS6KA1_ST	P01100	FOS	Q15418	RPS6KA1	S281	A276T	276	Missense	distal	-5	no	1.813	1.992	EPSD	TCGA;ICGC;COSMIC	1.787	Up-regulation
AGC_RSK_RSKp90_RPS6KA1_ST	Q96RK0	CIC	Q15418	RPS6KA1	S132	R139W	139	Missense	distal	7	no	1.847	1.852	EPSD	TCGA;COSMIC	1.787	Up-regulation
AGC_RSK_RSKp90_RPS6KA1_ST	Q96RK0	CIC	Q15418	RPS6KA1	S211	R215W	215	Missense	distal	4	no	1.826	1.836	EPSD	TCGA;COSMIC	1.787	Up-regulation
AGC_RSK_RSKp90_RPS6KA1_ST	Q96RK0	CIC	Q15418	RPS6KA1	S211	F210C	210	Missense	proximal	-1	no	1.826	1.857	EPSD	TCGA;COSMIC	1.787	Up-regulation
AGC_RSK_RSKp90_RPS6KA1_ST	Q96RK0	CIC	Q15418	RPS6KA1	S211	N205S	205	Missense	distal	-6	no	1.826	1.721	EPSD	TCGA;COSMIC	1.787	Loss
AGC_RSK_RSKp90_RPS6KA1_ST	Q96RK0	CIC	Q15418	RPS6KA1	S211	F210L	210	Missense	proximal	-1	no	1.826	1.648	EPSD	TCGA;COSMIC	1.787	Loss
AGC_RSK_RSKp90_RPS6KA1_ST	Q96RK0	CIC	Q15418	RPS6KA1	S211	R215Q	215	Missense	distal	4	no	1.826	1.831	EPSD	TCGA;COSMIC	1.787	Up-regulation
AGC_RSK_RSKp90_RPS6KA1_ST	Q96RK0	CIC	Q15418	RPS6KA1	S211	R213P	213	Missense	proximal	2	no	1.826	1.852	EPSD	TCGA;COSMIC	1.787	Up-regulation
AGC_RSK_RSKp90_RPS6KA1_ST	Q96RK0	CIC	Q15418	RPS6KA1	S211	R213Q	213	Missense	proximal	2	no	1.826	1.591	EPSD	TCGA;COSMIC	1.787	Loss
AGC_RSK_RSKp90_RPS6KA1_ST	Q96RK0	CIC	Q15418	RPS6KA1	T328	S335F	335	Missense	distal	7	no	1.900	1.959	EPSD	TCGA;ICGC;COSMIC	1.787	Up-regulation
AGC_RSK_RSKp90_RPS6KA1_ST	Q96RK0	CIC	Q15418	RPS6KA1	S333	S335F	335	Missense	proximal	2	no	2.187	2.259	EPSD	TCGA;ICGC;COSMIC	1.787	Up-regulation
AGC_RSK_RSKp90_RPS6KA1_ST	Q96RK0	CIC	Q15418	RPS6KA1	S333	R340W	340	Missense	distal	7	no	2.187	2.192	EPSD	TCGA;ICGC;COSMIC;GDSC	1.787	Up-regulation
AGC_RSK_RSKp90_RPS6KA1_ST	Q96RK0	CIC	Q15418	RPS6KA1	T421	R428H	428	Missense	distal	7	no	1.933	1.748	EPSD	TCGA;ICGC;COSMIC	1.787	Loss
AGC_RSK_RSKp90_RPS6KA1_ST	Q96RK0	CIC	Q15418	RPS6KA1	T421	P416A	416	Missense	distal	-5	no	1.933	1.820	EPSD	TCGA;ICGC;COSMIC	1.787	Down-regulation
AGC_RSK_RSKp90_RPS6KA1_ST	Q96RK0	CIC	Q15418	RPS6KA1	T421	P417S	417	Missense	distal	-4	no	1.933	1.742	EPSD	TCGA;ICGC;COSMIC	1.787	Loss
AGC_RSK_RSKp90_RPS6KA1_ST	Q96RK0	CIC	Q15418	RPS6KA1	T421	R422Q	422	Missense	proximal	1	no	1.933	1.952	EPSD	TCGA;ICGC;COSMIC	1.787	Up-regulation
AGC_RSK_RSKp90_RPS6KA1_ST	Q96RK0	CIC	Q15418	RPS6KA1	S431	D433N	433	Missense	proximal	2	no	2.264	2.126	EPSD	TCGA;ICGC;COSMIC	1.787	Down-regulation
AGC_RSK_RSKp90_RPS6KA1_ST	Q96RK0	CIC	Q15418	RPS6KA1	S431	R428H	428	Missense	distal	-3	no	2.264	1.846	EPSD	TCGA;ICGC;COSMIC	1.787	Down-regulation
AGC_RSK_RSKp90_RPS6KA1_ST	Q96RK0	CIC	Q15418	RPS6KA1	S431	M434I	434	Missense	distal	3	no	2.264	2.309	EPSD	TCGA;ICGC;COSMIC	1.787	Up-regulation
AGC_RSK_RSKp90_RPS6KA1_ST	Q96RK0	CIC	Q15418	RPS6KA1	S431	A430T	430	Missense	proximal	-1	no	2.264	2.449	EPSD	TCGA;ICGC;COSMIC	1.787	Up-regulation
AGC_RSK_RSKp90_RPS6KA1_ST	Q96RK0	CIC	Q15418	RPS6KA1	S479	E485Q	485	Missense	distal	6	no	2.030	1.827	EPSD	TCGA;ICGC;COSMIC	1.787	Down-regulation
AGC_RSK_RSKp90_RPS6KA1_ST	Q96RK0	CIC	Q15418	RPS6KA1	S479	E482K	482	Missense	distal	3	no	2.030	2.095	EPSD	TCGA;ICGC;COSMIC	1.787	Up-regulation
AGC_RSK_RSKp90_RPS6KA1_ST	Q96RK0	CIC	Q15418	RPS6KA1	S479	E475K	475	Missense	distal	-4	no	2.030	2.017	EPSD	TCGA;ICGC;COSMIC	1.787	Down-regulation
AGC_RSK_RSKp90_RPS6KA1_ST	Q96RK0	CIC	Q15418	RPS6KA1	S479	D473N	473	Missense	distal	-6	no	2.030	2.019	EPSD	TCGA;ICGC;COSMIC	1.787	Down-regulation
AGC_RSK_RSKp90_RPS6KA1_ST	Q96RK0	CIC	Q15418	RPS6KA1	S501	F495L	495	Missense	distal	-6	no	1.590	1.961	EPSD	TCGA;ICGC;COSMIC	1.787	Gain
AGC_RSK_RSKp90_RPS6KA1_ST	Q96RK0	CIC	Q15418	RPS6KA1	S502	F495L	495	Missense	distal	-7	no	1.897	1.898	EPSD	TCGA;ICGC;COSMIC	1.787	Up-regulation
AGC_RSK_RSKp90_RPS6KA1_ST	Q96RK0	CIC	Q15418	RPS6KA1	S502	S502F	502	Missense	central	0	yes	1.897	0.000	EPSD	TCGA;ICGC;COSMIC	1.787	Loss
AGC_RSK_RSKp90_RPS6KA1_ST	Q96RK0	CIC	Q15418	RPS6KA1	S502	S501F	501	Missense	proximal	-1	no	1.897	1.863	EPSD	TCGA;ICGC;COSMIC	1.787	Down-regulation
AGC_RSK_RSKp90_RPS6KA1_ST	Q96RK0	CIC	Q15418	RPS6KA1	T567	R572Q	572	Missense	distal	5	no	1.902	1.701	EPSD	TCGA;ICGC;COSMIC	1.787	Loss
AGC_RSK_RSKp90_RPS6KA1_ST	Q96RK0	CIC	Q15418	RPS6KA1	T567	P574S	574	Missense	distal	7	no	1.902	1.800	EPSD	TCGA;ICGC;COSMIC	1.787	Down-regulation
AGC_RSK_RSKp90_RPS6KA1_ST	Q96RK0	CIC	Q15418	RPS6KA1	T567	R572W	572	Missense	distal	5	no	1.902	1.716	EPSD	TCGA;COSMIC;GDSC;CCLE	1.787	Loss
AGC_RSK_RSKp90_RPS6KA1_ST	Q96RK0	CIC	Q15418	RPS6KA1	S585	A582P	582	Missense	distal	-3	no	2.007	1.510	EPSD	TCGA;ICGC;COSMIC	1.787	Loss
AGC_RSK_RSKp90_RPS6KA1_ST	Q96RK0	CIC	Q15418	RPS6KA1	S585	R589Q	589	Missense	distal	4	no	2.007	2.012	EPSD	TCGA;ICGC;COSMIC	1.787	Up-regulation
AGC_RSK_RSKp90_RPS6KA1_ST	Q96RK0	CIC	Q15418	RPS6KA1	S585	G580A	580	Missense	distal	-5	no	2.007	1.849	EPSD	TCGA;ICGC;COSMIC	1.787	Down-regulation
AGC_RSK_RSKp90_RPS6KA1_ST	Q96RK0	CIC	Q15418	RPS6KA1	S585	F590L	590	Missense	distal	5	no	2.007	2.000	EPSD	TCGA;ICGC;COSMIC	1.787	Down-regulation
AGC_RSK_RSKp90_RPS6KA1_ST	Q96RK0	CIC	Q15418	RPS6KA1	S585	R589W	589	Missense	distal	4	no	2.007	2.018	EPSD	TCGA;ICGC;COSMIC	1.787	Up-regulation
AGC_RSK_RSKp90_RPS6KA1_ST	Q96RK0	CIC	Q15418	RPS6KA1	S894	A900P	900	Missense	distal	6	no	2.127	2.117	EPSD	TCGA;ICGC;COSMIC	1.787	Down-regulation
AGC_RSK_RSKp90_RPS6KA1_ST	Q96RK0	CIC	Q15418	RPS6KA1	S894	S891P	891	Missense	distal	-3	no	2.127	2.028	EPSD	TCGA;ICGC	1.787	Down-regulation
AGC_RSK_RSKp90_RPS6KA1_ST	Q96RK0	CIC	Q15418	RPS6KA1	S932	P929A	929	Missense	distal	-3	no	1.469	1.965	EPSD	TCGA;ICGC;COSMIC	1.787	Gain
AGC_RSK_RSKp90_RPS6KA1_ST	Q96RK0	CIC	Q15418	RPS6KA1	T1217	E1224Q	1224	Missense	distal	7	no	1.925	1.963	EPSD	TCGA;ICGC;COSMIC	1.787	Up-regulation
AGC_RSK_RSKp90_RPS6KA1_ST	Q96RK0	CIC	Q15418	RPS6KA1	S1246	A1243T	1243	Missense	distal	-3	no	2.501	2.055	EPSD	TCGA	1.787	Down-regulation
AGC_RSK_RSKp90_RPS6KA1_ST	P25963	NFKBIA	Q15418	RPS6KA1	S166	L163R	163	Missense	distal	-3	no	1.820	1.736	EPSD	TCGA;COSMIC	1.787	Loss
AGC_RSK_RSKp90_RPS6KA1_ST	P25963	NFKBIA	Q15418	RPS6KA1	S283	E282K	282	Missense	proximal	-1	no	3.859	3.912	EPSD	TCGA;COSMIC	1.787	Up-regulation
AGC_RSK_RSKp90_RPS6KA1_ST	P25963	NFKBIA	Q15418	RPS6KA1	S283	D290G	290	Missense	distal	7	no	3.859	3.947	EPSD	TCGA	1.787	Up-regulation
TK_PDGFR_PDGFRA_Y	P16234	PDGFRA	P16234	PDGFRA	Y572	E571K	571	Missense	proximal	-1	no	13.678	13.579	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	8.840	Down-regulation
TK_PDGFR_PDGFRA_Y	P16234	PDGFRA	P16234	PDGFRA	Y572	Y572C	572	Missense	central	0	yes	13.678	0.000	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	8.840	Loss
TK_PDGFR_PDGFRA_Y	P16234	PDGFRA	P16234	PDGFRA	Y572	H570Y	570	Missense	proximal	-2	no	13.678	14.947	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	8.840	Up-regulation
TK_PDGFR_PDGFRA_Y	P16234	PDGFRA	P16234	PDGFRA	Y572	E571D	571	Missense	proximal	-1	no	13.678	13.566	EPSD;PhosphoSitePlus	TCGA;ICGC	8.840	Down-regulation
TK_PDGFR_PDGFRA_Y	P16234	PDGFRA	P16234	PDGFRA	Y572	P577L	577	Missense	distal	5	no	13.678	13.150	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	8.840	Down-regulation
TK_PDGFR_PDGFRA_Y	P16234	PDGFRA	P16234	PDGFRA	Y574	E571K	571	Missense	distal	-3	no	13.819	13.861	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	8.840	Up-regulation
TK_PDGFR_PDGFRA_Y	P16234	PDGFRA	P16234	PDGFRA	Y574	Y572C	572	Missense	proximal	-2	no	13.819	12.774	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	8.840	Down-regulation
TK_PDGFR_PDGFRA_Y	P16234	PDGFRA	P16234	PDGFRA	Y574	H570Y	570	Missense	distal	-4	no	13.819	13.057	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	8.840	Down-regulation
TK_PDGFR_PDGFRA_Y	P16234	PDGFRA	P16234	PDGFRA	Y574	L580P	580	Missense	distal	6	no	13.819	14.052	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	8.840	Up-regulation
TK_PDGFR_PDGFRA_Y	P16234	PDGFRA	P16234	PDGFRA	Y574	E571D	571	Missense	distal	-3	no	13.819	13.739	EPSD;PhosphoSitePlus	TCGA;ICGC	8.840	Down-regulation
TK_PDGFR_PDGFRA_Y	P16234	PDGFRA	P16234	PDGFRA	Y574	P577L	577	Missense	distal	3	no	13.819	14.545	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	8.840	Up-regulation
TK_PDGFR_PDGFRA_Y	P16234	PDGFRA	P16234	PDGFRA	Y720	E726Q	726	Missense	distal	6	no	14.620	15.411	EPSD	TCGA;ICGC;COSMIC	8.840	Up-regulation
TK_PDGFR_PDGFRA_Y	P16234	PDGFRA	P16234	PDGFRA	Y720	R718W	718	Missense	proximal	-2	no	14.620	12.052	EPSD	TCGA;ICGC;COSMIC	8.840	Down-regulation
TK_PDGFR_PDGFRA_Y	P16234	PDGFRA	P16234	PDGFRA	Y731	E726Q	726	Missense	distal	-5	no	14.394	15.595	EPSD	TCGA;ICGC;COSMIC	8.840	Up-regulation
TK_PDGFR_PDGFRA_Y	P16234	PDGFRA	P16234	PDGFRA	Y731	G729V	729	Missense	proximal	-2	no	14.394	11.345	EPSD	TCGA;ICGC;COSMIC	8.840	Down-regulation
TK_PDGFR_PDGFRA_Y	P16234	PDGFRA	P16234	PDGFRA	Y731	M734T	734	Missense	distal	3	no	14.394	12.443	EPSD	TCGA;ICGC;COSMIC	8.840	Down-regulation
TK_PDGFR_PDGFRA_Y	P16234	PDGFRA	P16234	PDGFRA	Y742	R748K	748	Missense	distal	6	no	23.643	22.759	EPSD	TCGA;ICGC;COSMIC	8.840	Down-regulation
TK_PDGFR_PDGFRA_Y	P16234	PDGFRA	P16234	PDGFRA	Y742	V743A	743	Missense	proximal	1	no	23.643	21.065	EPSD	TCGA;ICGC;COSMIC	8.840	Down-regulation
TK_PDGFR_PDGFRA_Y	P16234	PDGFRA	P16234	PDGFRA	Y742	T740A	740	Missense	proximal	-2	no	23.643	24.984	EPSD	TCGA;ICGC	8.840	Up-regulation
TK_PDGFR_PDGFRA_Y	P16234	PDGFRA	P16234	PDGFRA	Y754	R748K	748	Missense	distal	-6	no	20.901	18.511	EPSD	TCGA;ICGC;COSMIC	8.840	Down-regulation
TK_PDGFR_PDGFRA_Y	P16234	PDGFRA	P16234	PDGFRA	Y762	R764H	764	Missense	proximal	2	no	14.790	14.162	EPSD	TCGA;ICGC;COSMIC	8.840	Down-regulation
TK_PDGFR_PDGFRA_Y	P16234	PDGFRA	P16234	PDGFRA	Y762	D763G	763	Missense	proximal	1	no	14.790	14.450	EPSD	TCGA;ICGC	8.840	Down-regulation
TK_PDGFR_PDGFRA_Y	P16234	PDGFRA	P16234	PDGFRA	Y768	R764H	764	Missense	distal	-4	no	14.461	14.264	EPSD	TCGA;ICGC;COSMIC	8.840	Down-regulation
TK_PDGFR_PDGFRA_Y	P16234	PDGFRA	P16234	PDGFRA	Y768	K770N	770	Missense	proximal	2	no	14.461	14.990	EPSD	TCGA;ICGC;COSMIC;CCLE	8.840	Up-regulation
TK_PDGFR_PDGFRA_Y	P16234	PDGFRA	P16234	PDGFRA	Y768	D763G	763	Missense	distal	-5	no	14.461	16.024	EPSD	TCGA;ICGC	8.840	Up-regulation
TK_PDGFR_PDGFRA_Y	P16234	PDGFRA	P16234	PDGFRA	Y849	D842Y	842	Missense	distal	-7	no	9.824	10.721	EPSD	TCGA;ICGC;COSMIC	8.840	Up-regulation
TK_PDGFR_PDGFRA_Y	P16234	PDGFRA	P16234	PDGFRA	Y849	S847L	847	Missense	proximal	-2	no	9.824	5.576	EPSD	TCGA;ICGC;COSMIC	8.840	Loss
TK_PDGFR_PDGFRA_Y	P16234	PDGFRA	P16234	PDGFRA	Y849	S851L	851	Missense	proximal	2	no	9.824	11.076	EPSD	TCGA;ICGC;COSMIC	8.840	Up-regulation
TK_PDGFR_PDGFRA_Y	P16234	PDGFRA	P16234	PDGFRA	Y988	R981P	981	Missense	distal	-7	no	24.666	23.307	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	8.840	Down-regulation
TK_PDGFR_PDGFRA_Y	P16234	PDGFRA	P16234	PDGFRA	Y988	D985N	985	Missense	distal	-3	no	24.666	24.861	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	8.840	Up-regulation
TK_PDGFR_PDGFRA_Y	P16234	PDGFRA	P16234	PDGFRA	Y988	V982M	982	Missense	distal	-6	no	24.666	24.422	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	8.840	Down-regulation
TK_PDGFR_PDGFRA_Y	P16234	PDGFRA	P16234	PDGFRA	Y988	A987E	987	Missense	proximal	-1	no	24.666	24.764	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	8.840	Up-regulation
TK_PDGFR_PDGFRA_Y	P16234	PDGFRA	P16234	PDGFRA	Y988	R981C	981	Missense	distal	-7	no	24.666	22.804	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC;GDSC;CCLE	8.840	Down-regulation
TK_PDGFR_PDGFRA_Y	P16234	PDGFRA	P16234	PDGFRA	Y988	V982L	982	Missense	distal	-6	no	24.666	24.429	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	8.840	Down-regulation
TK_PDGFR_PDGFRA_Y	P16234	PDGFRA	P16234	PDGFRA	Y988	R981H	981	Missense	distal	-7	no	24.666	22.913	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	8.840	Down-regulation
TK_PDGFR_PDGFRA_Y	P16234	PDGFRA	P16234	PDGFRA	Y1018	P1021L	1021	Missense	distal	3	no	20.400	21.126	PhosphoSitePlus;EPSD	TCGA;ICGC;COSMIC	8.840	Up-regulation
TK_PDGFR_PDGFRA_Y	P16234	PDGFRA	P16234	PDGFRA	Y1018	S1013G	1013	Missense	distal	-5	no	20.400	21.160	PhosphoSitePlus;EPSD	TCGA;ICGC;COSMIC	8.840	Up-regulation
TK_PDGFR_PDGFRA_Y	P16234	PDGFRA	P16234	PDGFRA	Y1018	A1014T	1014	Missense	distal	-4	no	20.400	19.694	PhosphoSitePlus;EPSD	TCGA;ICGC;COSMIC	8.840	Down-regulation
TK_PDGFR_PDGFRA_Y	P16234	PDGFRA	P16234	PDGFRA	Y1018	D1015V	1015	Missense	distal	-3	no	20.400	20.559	PhosphoSitePlus;EPSD	TCGA;ICGC	8.840	Up-regulation
TK_PDGFR_PDGFRA_Y	Q9P219	CCDC88C	P16234	PDGFRA	Y1272	H1266R	1266	Missense	distal	-6	no	7.287	9.062	EPSD	TCGA;ICGC;COSMIC	8.840	Gain
TK_PDGFR_PDGFRA_Y	Q9P219	CCDC88C	P16234	PDGFRA	Y1395	F1394L	1394	Missense	proximal	-1	no	9.006	9.046	EPSD	TCGA;ICGC;COSMIC	8.840	Up-regulation
TK_PDGFR_PDGFRA_Y	Q9P219	CCDC88C	P16234	PDGFRA	Y1395	K1400N	1400	Missense	distal	5	no	9.006	8.933	EPSD	TCGA;ICGC;COSMIC	8.840	Down-regulation
TK_PDGFR_PDGFRA_Y	Q9P219	CCDC88C	P16234	PDGFRA	Y2025	V2021M	2021	Missense	distal	-4	no	9.166	9.018	PhosphoSitePlus	TCGA;COSMIC	8.840	Down-regulation
TK_PDGFR_PDGFRA_Y	Q9P219	CCDC88C	P16234	PDGFRA	Y2025	Y2023N	2023	Missense	proximal	-2	no	9.166	9.505	PhosphoSitePlus	TCGA;ICGC;COSMIC	8.840	Up-regulation
TK_PDGFR_PDGFRA_Y	P12931	SRC	P16234	PDGFRA	Y419	A425V	425	Missense	distal	6	no	18.156	19.309	PhosphoSitePlus	TCGA;ICGC;COSMIC;CCLE	8.840	Up-regulation
AGC_GRK_BARK_GRK2_ST	P25101	EDNRA	P25098	GRK2	T403	S397L	397	Missense	distal	-6	no	135.683	129.128	EPSD;PhosphoSitePlus	TCGA;COSMIC	128.034	Down-regulation
AGC_GRK_BARK_GRK2_ST	P25101	EDNRA	P25098	GRK2	T403	I405F	405	Missense	proximal	2	no	135.683	143.255	EPSD;PhosphoSitePlus	TCGA;COSMIC	128.034	Up-regulation
AGC_GRK_BARK_GRK2_ST	P25101	EDNRA	P25098	GRK2	T403	I405V	405	Missense	proximal	2	no	135.683	148.562	EPSD;PhosphoSitePlus	TCGA;COSMIC	128.034	Up-regulation
AGC_GRK_BARK_GRK2_ST	P25101	EDNRA	P25098	GRK2	T403	G402E	402	Missense	proximal	-1	no	135.683	137.776	EPSD;PhosphoSitePlus	TCGA;COSMIC	128.034	Up-regulation
AGC_GRK_BARK_GRK2_ST	P25101	EDNRA	P25098	GRK2	S404	S397L	397	Missense	distal	-7	no	127.709	131.230	EPSD;PhosphoSitePlus	TCGA;COSMIC	128.034	Gain
AGC_GRK_BARK_GRK2_ST	P25101	EDNRA	P25098	GRK2	S404	I405F	405	Missense	proximal	1	no	127.709	144.115	EPSD;PhosphoSitePlus	TCGA;COSMIC	128.034	Gain
AGC_GRK_BARK_GRK2_ST	P25101	EDNRA	P25098	GRK2	S404	D411N	411	Missense	distal	7	no	127.709	128.441	EPSD;PhosphoSitePlus	TCGA;COSMIC	128.034	Gain
AGC_GRK_BARK_GRK2_ST	P25101	EDNRA	P25098	GRK2	S404	I405V	405	Missense	proximal	1	no	127.709	147.505	EPSD;PhosphoSitePlus	TCGA;COSMIC	128.034	Gain
AGC_GRK_BARK_GRK2_ST	P25101	EDNRA	P25098	GRK2	S404	G402E	402	Missense	proximal	-2	no	127.709	141.881	EPSD;PhosphoSitePlus	TCGA;COSMIC	128.034	Gain
AGC_GRK_BARK_GRK2_ST	P25101	EDNRA	P25098	GRK2	T417	Q412E	412	Missense	distal	-5	no	147.721	153.626	EPSD	TCGA;COSMIC	128.034	Up-regulation
AGC_GRK_BARK_GRK2_ST	P25101	EDNRA	P25098	GRK2	T417	D411N	411	Missense	distal	-6	no	147.721	146.403	EPSD	TCGA;COSMIC	128.034	Down-regulation
AGC_GRK_BARK_GRK2_ST	P25101	EDNRA	P25098	GRK2	T417	R419Q	419	Missense	proximal	2	no	147.721	147.556	EPSD	TCGA;COSMIC	128.034	Down-regulation
AGC_GRK_BARK_GRK2_ST	P25101	EDNRA	P25098	GRK2	S420	R419Q	419	Missense	proximal	-1	no	172.684	172.026	EPSD	TCGA;COSMIC	128.034	Down-regulation
AGC_GRK_BARK_GRK2_ST	P25101	EDNRA	P25098	GRK2	S421	R419Q	419	Missense	proximal	-2	no	163.010	165.714	EPSD	TCGA;COSMIC	128.034	Up-regulation
AGC_GRK_BARK_GRK2_ST	P25101	EDNRA	P25098	GRK2	S425	R419Q	419	Missense	distal	-6	no	151.589	156.492	EPSD	TCGA;COSMIC	128.034	Up-regulation
AGC_GRK_BARK_GRK2_ST	P35241	RDX	P25098	GRK2	T518	E517D	517	Missense	proximal	-1	no	130.436	135.938	EPSD	TCGA;ICGC	128.034	Up-regulation
AGC_GRK_BARK_GRK2_ST	P35241	RDX	P25098	GRK2	T545	K543N	543	Missense	proximal	-2	no	129.999	133.622	EPSD	TCGA	128.034	Up-regulation
AGC_GRK_BARK_GRK2_ST	P35241	RDX	P25098	GRK2	T564	R569Q	569	Missense	distal	5	no	167.189	168.295	PhosphoSitePlus	TCGA;ICGC	128.034	Up-regulation
AGC_GRK_BARK_GRK2_ST	P35241	RDX	P25098	GRK2	T564	D560Y	560	Missense	distal	-4	no	167.189	163.500	PhosphoSitePlus	TCGA;COSMIC	128.034	Down-regulation
AGC_GRK_BARK_GRK2_ST	P35241	RDX	P25098	GRK2	T564	R566Q	566	Missense	proximal	2	no	167.189	167.024	PhosphoSitePlus	TCGA;COSMIC	128.034	Down-regulation
AGC_GRK_BARK_GRK2_ST	P35241	RDX	P25098	GRK2	T564	A557T	557	Missense	distal	-7	no	167.189	167.165	PhosphoSitePlus	TCGA;ICGC;COSMIC	128.034	Down-regulation
AGC_GRK_BARK_GRK2_ST	P41143	OPRD1	P25098	GRK2	S249	S242T	242	Missense	distal	-7	no	126.598	130.453	EPSD	TCGA;ICGC;COSMIC	128.034	Gain
AGC_GRK_BARK_GRK2_ST	P41143	OPRD1	P25098	GRK2	S344	A348T	348	Missense	distal	4	no	141.487	139.397	EPSD	TCGA;ICGC;COSMIC	128.034	Down-regulation
AGC_GRK_BARK_GRK2_ST	P41143	OPRD1	P25098	GRK2	S344	G338S	338	Missense	distal	-6	no	141.487	144.393	EPSD	TCGA;ICGC;COSMIC	128.034	Up-regulation
AGC_GRK_BARK_GRK2_ST	P41143	OPRD1	P25098	GRK2	T358	R356L	356	Missense	proximal	-2	no	155.406	153.514	EPSD	TCGA	128.034	Down-regulation
AGC_GRK_BARK_GRK2_ST	P41143	OPRD1	P25098	GRK2	T361	G367S	367	Missense	distal	6	no	152.449	151.664	EPSD	TCGA;ICGC;COSMIC	128.034	Down-regulation
AGC_GRK_BARK_GRK2_ST	P41143	OPRD1	P25098	GRK2	T361	R356L	356	Missense	distal	-5	no	152.449	138.352	EPSD	TCGA	128.034	Down-regulation
AGC_GRK_BARK_GRK2_ST	P41143	OPRD1	P25098	GRK2	S363	G367S	367	Missense	distal	4	no	149.684	153.059	PhosphoSitePlus	TCGA;ICGC;COSMIC	128.034	Up-regulation
AGC_GRK_BARK_GRK2_ST	P41143	OPRD1	P25098	GRK2	S363	R356L	356	Missense	distal	-7	no	149.684	149.142	PhosphoSitePlus	TCGA	128.034	Down-regulation
AGC_GRK_BARK_GRK2_ST	P15311	EZR	P25098	GRK2	T332	R330T	330	Missense	proximal	-2	no	146.185	148.041	EPSD	TCGA;ICGC;COSMIC	128.034	Up-regulation
AGC_GRK_BARK_GRK2_ST	P15311	EZR	P25098	GRK2	S366	E364D	364	Missense	proximal	-2	no	126.864	130.070	EPSD	TCGA;ICGC	128.034	Gain
AGC_GRK_BARK_GRK2_ST	P15311	EZR	P25098	GRK2	S539	L538V	538	Missense	proximal	-1	no	126.245	133.365	EPSD	TCGA;ICGC;COSMIC	128.034	Gain
AGC_GRK_BARK_GRK2_ST	P15311	EZR	P25098	GRK2	S539	A541V	541	Missense	proximal	2	no	126.245	133.168	EPSD	TCGA;ICGC;COSMIC	128.034	Gain
AGC_GRK_BARK_GRK2_ST	P15311	EZR	P25098	GRK2	T548	N550K	550	Missense	proximal	2	no	143.837	143.430	EPSD	TCGA;ICGC;COSMIC	128.034	Down-regulation
AGC_GRK_BARK_GRK2_ST	P15311	EZR	P25098	GRK2	T548	A541V	541	Missense	distal	-7	no	143.837	141.599	EPSD	TCGA;ICGC;COSMIC	128.034	Down-regulation
AGC_GRK_BARK_GRK2_ST	P15311	EZR	P25098	GRK2	T567	R562Q	562	Missense	distal	-5	no	162.201	157.842	PhosphoSitePlus	TCGA;ICGC	128.034	Down-regulation
AGC_GRK_BARK_GRK2_ST	P15311	EZR	P25098	GRK2	T567	R569Q	569	Missense	proximal	2	no	162.201	162.036	PhosphoSitePlus	TCGA;ICGC;COSMIC	128.034	Down-regulation
AGC_GRK_BARK_GRK2_ST	P15311	EZR	P25098	GRK2	T576	R569Q	569	Missense	distal	-7	no	131.411	129.583	EPSD	TCGA;ICGC;COSMIC	128.034	Down-regulation
AGC_GRK_BARK_GRK2_ST	P07550	ADRB2	P25098	GRK2	T393	S396R	396	Missense	distal	3	no	129.526	133.915	EPSD	TCGA;ICGC;COSMIC	128.034	Up-regulation
AGC_GRK_BARK_GRK2_ST	P07550	ADRB2	P25098	GRK2	T393	P395A	395	Missense	proximal	2	no	129.526	126.140	EPSD	TCGA;ICGC;COSMIC;GDSC;CCLE	128.034	Loss
AGC_GRK_BARK_GRK2_ST	P07550	ADRB2	P25098	GRK2	T393	D400N	400	Missense	distal	7	no	129.526	130.258	EPSD	TCGA;ICGC;COSMIC	128.034	Up-regulation
AGC_GRK_BARK_GRK2_ST	P07550	ADRB2	P25098	GRK2	T393	T393N	393	Missense	central	0	yes	129.526	0.000	EPSD	TCGA;ICGC	128.034	Loss
AGC_GRK_BARK_GRK2_ST	P07550	ADRB2	P25098	GRK2	T393	D397N	397	Missense	distal	4	no	129.526	127.443	EPSD	TCGA;ICGC	128.034	Loss
AGC_GRK_BARK_GRK2_ST	P07550	ADRB2	P25098	GRK2	S396	S396R	396	Missense	central	0	yes	164.934	0.000	PhosphoSitePlus;EPSD	TCGA;ICGC;COSMIC	128.034	Loss
AGC_GRK_BARK_GRK2_ST	P07550	ADRB2	P25098	GRK2	S396	P395A	395	Missense	proximal	-1	no	164.934	148.879	PhosphoSitePlus;EPSD	TCGA;ICGC;COSMIC;GDSC;CCLE	128.034	Down-regulation
AGC_GRK_BARK_GRK2_ST	P07550	ADRB2	P25098	GRK2	S396	D400N	400	Missense	distal	4	no	164.934	162.851	PhosphoSitePlus;EPSD	TCGA;ICGC;COSMIC	128.034	Down-regulation
AGC_GRK_BARK_GRK2_ST	P07550	ADRB2	P25098	GRK2	S396	T393N	393	Missense	distal	-3	no	164.934	161.453	PhosphoSitePlus;EPSD	TCGA;ICGC	128.034	Down-regulation
AGC_GRK_BARK_GRK2_ST	P07550	ADRB2	P25098	GRK2	S396	D397N	397	Missense	proximal	1	no	164.934	163.500	PhosphoSitePlus;EPSD	TCGA;ICGC	128.034	Down-regulation
AGC_GRK_BARK_GRK2_ST	P07550	ADRB2	P25098	GRK2	S401	S396R	396	Missense	distal	-5	no	165.208	169.976	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	128.034	Up-regulation
AGC_GRK_BARK_GRK2_ST	P07550	ADRB2	P25098	GRK2	S401	P395A	395	Missense	distal	-6	no	165.208	169.442	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC;GDSC;CCLE	128.034	Up-regulation
AGC_GRK_BARK_GRK2_ST	P07550	ADRB2	P25098	GRK2	S401	D400N	400	Missense	proximal	-1	no	165.208	161.011	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	128.034	Down-regulation
AGC_GRK_BARK_GRK2_ST	P07550	ADRB2	P25098	GRK2	S401	D397N	397	Missense	distal	-4	no	165.208	153.353	EPSD;PhosphoSitePlus	TCGA;ICGC	128.034	Down-regulation
AGC_GRK_BARK_GRK2_ST	P07550	ADRB2	P25098	GRK2	S407	D400N	400	Missense	distal	-7	no	147.963	149.221	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	128.034	Up-regulation
AGC_GRK_BARK_GRK2_ST	Q14940	SLC9A5	P25098	GRK2	S741	E743Q	743	Missense	proximal	2	no	142.504	140.248	EPSD	TCGA;ICGC;COSMIC	128.034	Down-regulation
AGC_GRK_BARK_GRK2_ST	Q14940	SLC9A5	P25098	GRK2	S741	G736S	736	Missense	distal	-5	no	142.504	140.291	EPSD	TCGA;ICGC;COSMIC	128.034	Down-regulation
AGC_GRK_BARK_GRK2_ST	P08172	CHRM2	P25098	GRK2	S232	S232F	232	Missense	central	0	yes	135.315	0.000	EPSD;PhosphoSitePlus	TCGA;COSMIC	128.034	Loss
AGC_GRK_BARK_GRK2_ST	P08172	CHRM2	P25098	GRK2	S232	G238R	238	Missense	distal	6	no	135.315	136.798	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	128.034	Up-regulation
AGC_GRK_BARK_GRK2_ST	P08172	CHRM2	P25098	GRK2	S232	R239G	239	Missense	distal	7	no	135.315	135.405	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	128.034	Up-regulation
AGC_GRK_BARK_GRK2_ST	P08172	CHRM2	P25098	GRK2	S232	D229E	229	Missense	distal	-3	no	135.315	138.521	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	128.034	Up-regulation
AGC_GRK_BARK_GRK2_ST	P08172	CHRM2	P25098	GRK2	S232	N227K	227	Missense	distal	-5	no	135.315	137.793	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	128.034	Up-regulation
AGC_GRK_BARK_GRK2_ST	P08172	CHRM2	P25098	GRK2	S232	Q228H	228	Missense	distal	-4	no	135.315	125.116	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	128.034	Loss
AGC_GRK_BARK_GRK2_ST	P08172	CHRM2	P25098	GRK2	S232	D229Y	229	Missense	distal	-3	no	135.315	121.261	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	128.034	Loss
AGC_GRK_BARK_GRK2_ST	P08172	CHRM2	P25098	GRK2	S232	V225I	225	Missense	distal	-7	no	135.315	138.612	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	128.034	Up-regulation
AGC_GRK_BARK_GRK2_ST	P08172	CHRM2	P25098	GRK2	S232	S232Y	232	Missense	central	0	yes	135.315	0.000	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	128.034	Loss
AGC_GRK_BARK_GRK2_ST	P08172	CHRM2	P25098	GRK2	S232	R239K	239	Missense	distal	7	no	135.315	135.137	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	128.034	Down-regulation
AGC_GRK_BARK_GRK2_ST	P08172	CHRM2	P25098	GRK2	S232	S234N	234	Missense	proximal	2	no	135.315	135.985	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	128.034	Up-regulation
AGC_GRK_BARK_GRK2_ST	P08172	CHRM2	P25098	GRK2	S232	P230L	230	Missense	proximal	-2	no	135.315	131.285	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	128.034	Down-regulation
AGC_GRK_BARK_GRK2_ST	P08172	CHRM2	P25098	GRK2	S234	S232F	232	Missense	proximal	-2	no	135.010	113.735	EPSD;PhosphoSitePlus	TCGA;COSMIC	128.034	Loss
AGC_GRK_BARK_GRK2_ST	P08172	CHRM2	P25098	GRK2	S234	G238R	238	Missense	distal	4	no	135.010	139.449	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	128.034	Up-regulation
AGC_GRK_BARK_GRK2_ST	P08172	CHRM2	P25098	GRK2	S234	R239G	239	Missense	distal	5	no	135.010	136.608	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	128.034	Up-regulation
AGC_GRK_BARK_GRK2_ST	P08172	CHRM2	P25098	GRK2	S234	D229E	229	Missense	distal	-5	no	135.010	135.935	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	128.034	Up-regulation
AGC_GRK_BARK_GRK2_ST	P08172	CHRM2	P25098	GRK2	S234	N227K	227	Missense	distal	-7	no	135.010	135.836	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	128.034	Up-regulation
AGC_GRK_BARK_GRK2_ST	P08172	CHRM2	P25098	GRK2	S234	Q228H	228	Missense	distal	-6	no	135.010	128.128	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	128.034	Down-regulation
AGC_GRK_BARK_GRK2_ST	P08172	CHRM2	P25098	GRK2	S234	D229Y	229	Missense	distal	-5	no	135.010	127.663	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	128.034	Loss
AGC_GRK_BARK_GRK2_ST	P08172	CHRM2	P25098	GRK2	S234	S232Y	232	Missense	proximal	-2	no	135.010	137.230	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	128.034	Up-regulation
AGC_GRK_BARK_GRK2_ST	P08172	CHRM2	P25098	GRK2	S234	R239K	239	Missense	distal	5	no	135.010	134.216	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	128.034	Down-regulation
AGC_GRK_BARK_GRK2_ST	P08172	CHRM2	P25098	GRK2	S234	S234N	234	Missense	central	0	yes	135.010	0.000	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	128.034	Loss
AGC_GRK_BARK_GRK2_ST	P08172	CHRM2	P25098	GRK2	S234	P230L	230	Missense	distal	-4	no	135.010	138.638	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	128.034	Up-regulation
AGC_GRK_BARK_GRK2_ST	P08172	CHRM2	P25098	GRK2	S250	D252Y	252	Missense	proximal	2	no	154.968	154.090	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	128.034	Down-regulation
AGC_GRK_BARK_GRK2_ST	P08172	CHRM2	P25098	GRK2	S250	G254D	254	Missense	distal	4	no	154.968	157.141	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	128.034	Up-regulation
AGC_GRK_BARK_GRK2_ST	P08172	CHRM2	P25098	GRK2	S250	M248I	248	Missense	proximal	-2	no	154.968	148.317	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	128.034	Down-regulation
AGC_GRK_BARK_GRK2_ST	P08172	CHRM2	P25098	GRK2	S250	D252E	252	Missense	proximal	2	no	154.968	157.469	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	128.034	Up-regulation
AGC_GRK_BARK_GRK2_ST	P08172	CHRM2	P25098	GRK2	S250	S250R	250	Missense	central	0	yes	154.968	0.000	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	128.034	Loss
AGC_GRK_BARK_GRK2_ST	P08172	CHRM2	P25098	GRK2	S250	D253E	253	Missense	distal	3	no	154.968	159.389	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	128.034	Up-regulation
AGC_GRK_BARK_GRK2_ST	P08172	CHRM2	P25098	GRK2	S250	S251I	251	Missense	proximal	1	no	154.968	129.679	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	128.034	Down-regulation
AGC_GRK_BARK_GRK2_ST	P08172	CHRM2	P25098	GRK2	S250	D253N	253	Missense	distal	3	no	154.968	154.633	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	128.034	Down-regulation
AGC_GRK_BARK_GRK2_ST	P08172	CHRM2	P25098	GRK2	S250	P249S	249	Missense	proximal	-1	no	154.968	151.030	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC;GDSC;CCLE	128.034	Down-regulation
AGC_GRK_BARK_GRK2_ST	P08172	CHRM2	P25098	GRK2	S251	D252Y	252	Missense	proximal	1	no	143.627	133.871	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	128.034	Down-regulation
AGC_GRK_BARK_GRK2_ST	P08172	CHRM2	P25098	GRK2	S251	G254D	254	Missense	distal	3	no	143.627	142.847	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	128.034	Down-regulation
AGC_GRK_BARK_GRK2_ST	P08172	CHRM2	P25098	GRK2	S251	M248I	248	Missense	distal	-3	no	143.627	114.557	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	128.034	Loss
AGC_GRK_BARK_GRK2_ST	P08172	CHRM2	P25098	GRK2	S251	D252E	252	Missense	proximal	1	no	143.627	145.429	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	128.034	Up-regulation
AGC_GRK_BARK_GRK2_ST	P08172	CHRM2	P25098	GRK2	S251	S250R	250	Missense	proximal	-1	no	143.627	140.059	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	128.034	Down-regulation
AGC_GRK_BARK_GRK2_ST	P08172	CHRM2	P25098	GRK2	S251	D253E	253	Missense	proximal	2	no	143.627	146.128	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	128.034	Up-regulation
AGC_GRK_BARK_GRK2_ST	P08172	CHRM2	P25098	GRK2	S251	S251I	251	Missense	central	0	yes	143.627	0.000	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	128.034	Loss
AGC_GRK_BARK_GRK2_ST	P08172	CHRM2	P25098	GRK2	S251	D253N	253	Missense	proximal	2	no	143.627	141.842	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	128.034	Down-regulation
AGC_GRK_BARK_GRK2_ST	P08172	CHRM2	P25098	GRK2	S251	P249S	249	Missense	proximal	-2	no	143.627	147.793	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC;GDSC;CCLE	128.034	Up-regulation
AGC_GRK_BARK_GRK2_ST	P08172	CHRM2	P25098	GRK2	T271	A265S	265	Missense	distal	-6	no	142.748	144.682	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	128.034	Up-regulation
AGC_GRK_BARK_GRK2_ST	P08172	CHRM2	P25098	GRK2	T271	G277E	277	Missense	distal	6	no	142.748	144.337	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	128.034	Up-regulation
AGC_GRK_BARK_GRK2_ST	P08172	CHRM2	P25098	GRK2	T271	C274S	274	Missense	distal	3	no	142.748	137.819	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	128.034	Down-regulation
AGC_GRK_BARK_GRK2_ST	P08172	CHRM2	P25098	GRK2	T271	V270A	270	Missense	proximal	-1	no	142.748	133.229	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	128.034	Down-regulation
AGC_GRK_BARK_GRK2_ST	P08172	CHRM2	P25098	GRK2	T271	Q276R	276	Missense	distal	5	no	142.748	141.642	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	128.034	Down-regulation
AGC_GRK_BARK_GRK2_ST	P08172	CHRM2	P25098	GRK2	T271	E272D	272	Missense	proximal	1	no	142.748	140.946	EPSD;PhosphoSitePlus	TCGA;ICGC	128.034	Down-regulation
AGC_GRK_BARK_GRK2_ST	P08172	CHRM2	P25098	GRK2	T271	E278D	278	Missense	distal	7	no	142.748	142.442	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	128.034	Down-regulation
AGC_GRK_BARK_GRK2_ST	P08172	CHRM2	P25098	GRK2	S282	G277E	277	Missense	distal	-5	no	152.972	157.074	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	128.034	Up-regulation
AGC_GRK_BARK_GRK2_ST	P08172	CHRM2	P25098	GRK2	S282	E279K	279	Missense	distal	-3	no	152.972	131.542	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	128.034	Down-regulation
AGC_GRK_BARK_GRK2_ST	P08172	CHRM2	P25098	GRK2	S282	S288L	288	Missense	distal	6	no	152.972	151.477	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	128.034	Down-regulation
AGC_GRK_BARK_GRK2_ST	P08172	CHRM2	P25098	GRK2	S282	Q276R	276	Missense	distal	-6	no	152.972	148.069	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	128.034	Down-regulation
AGC_GRK_BARK_GRK2_ST	P08172	CHRM2	P25098	GRK2	S282	E278D	278	Missense	distal	-4	no	152.972	162.713	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	128.034	Up-regulation
AGC_GRK_BARK_GRK2_ST	P08172	CHRM2	P25098	GRK2	S283	G277E	277	Missense	distal	-6	no	138.399	143.445	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	128.034	Up-regulation
AGC_GRK_BARK_GRK2_ST	P08172	CHRM2	P25098	GRK2	S283	E279K	279	Missense	distal	-4	no	138.399	133.307	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	128.034	Down-regulation
AGC_GRK_BARK_GRK2_ST	P08172	CHRM2	P25098	GRK2	S283	S288L	288	Missense	distal	5	no	138.399	132.630	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	128.034	Down-regulation
AGC_GRK_BARK_GRK2_ST	P08172	CHRM2	P25098	GRK2	S283	Q276R	276	Missense	distal	-7	no	138.399	140.227	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	128.034	Up-regulation
AGC_GRK_BARK_GRK2_ST	P08172	CHRM2	P25098	GRK2	S283	E278D	278	Missense	distal	-5	no	138.399	137.474	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	128.034	Down-regulation
AGC_GRK_BARK_GRK2_ST	P08172	CHRM2	P25098	GRK2	S286	V292L	292	Missense	distal	6	no	149.588	145.771	EPSD;PhosphoSitePlus	TCGA;ICGC	128.034	Down-regulation
AGC_GRK_BARK_GRK2_ST	P08172	CHRM2	P25098	GRK2	S286	A291S	291	Missense	distal	5	no	149.588	151.921	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	128.034	Up-regulation
AGC_GRK_BARK_GRK2_ST	P08172	CHRM2	P25098	GRK2	S286	E279K	279	Missense	distal	-7	no	149.588	149.977	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	128.034	Up-regulation
AGC_GRK_BARK_GRK2_ST	P08172	CHRM2	P25098	GRK2	S286	S288L	288	Missense	proximal	2	no	149.588	144.921	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	128.034	Down-regulation
AGC_GRK_BARK_GRK2_ST	P08172	CHRM2	P25098	GRK2	S286	A291D	291	Missense	distal	5	no	149.588	152.870	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	128.034	Up-regulation
AGC_GRK_BARK_GRK2_ST	P08172	CHRM2	P25098	GRK2	T287	V292L	292	Missense	distal	5	no	162.650	158.764	EPSD;PhosphoSitePlus	TCGA;ICGC	128.034	Down-regulation
AGC_GRK_BARK_GRK2_ST	P08172	CHRM2	P25098	GRK2	T287	A291S	291	Missense	distal	4	no	162.650	165.876	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	128.034	Up-regulation
AGC_GRK_BARK_GRK2_ST	P08172	CHRM2	P25098	GRK2	T287	S288L	288	Missense	proximal	1	no	162.650	157.537	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	128.034	Down-regulation
AGC_GRK_BARK_GRK2_ST	P08172	CHRM2	P25098	GRK2	T287	A291D	291	Missense	distal	4	no	162.650	164.675	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	128.034	Up-regulation
AGC_GRK_BARK_GRK2_ST	P08172	CHRM2	P25098	GRK2	S288	V292L	292	Missense	distal	4	no	156.673	141.508	EPSD;PhosphoSitePlus	TCGA;ICGC	128.034	Down-regulation
AGC_GRK_BARK_GRK2_ST	P08172	CHRM2	P25098	GRK2	S288	A291S	291	Missense	distal	3	no	156.673	157.989	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	128.034	Up-regulation
AGC_GRK_BARK_GRK2_ST	P08172	CHRM2	P25098	GRK2	S288	S288L	288	Missense	central	0	yes	156.673	0.000	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	128.034	Loss
AGC_GRK_BARK_GRK2_ST	P08172	CHRM2	P25098	GRK2	S288	A291D	291	Missense	distal	3	no	156.673	159.691	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	128.034	Up-regulation
AGC_GRK_BARK_GRK2_ST	P08172	CHRM2	P25098	GRK2	S290	M296I	296	Missense	distal	6	no	145.638	144.965	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	128.034	Down-regulation
AGC_GRK_BARK_GRK2_ST	P08172	CHRM2	P25098	GRK2	S290	V292L	292	Missense	proximal	2	no	145.638	137.157	EPSD;PhosphoSitePlus	TCGA;ICGC	128.034	Down-regulation
AGC_GRK_BARK_GRK2_ST	P08172	CHRM2	P25098	GRK2	S290	A291S	291	Missense	proximal	1	no	145.638	155.769	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	128.034	Up-regulation
AGC_GRK_BARK_GRK2_ST	P08172	CHRM2	P25098	GRK2	S290	S288L	288	Missense	proximal	-2	no	145.638	137.441	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	128.034	Down-regulation
AGC_GRK_BARK_GRK2_ST	P08172	CHRM2	P25098	GRK2	S290	A291D	291	Missense	proximal	1	no	145.638	158.062	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	128.034	Up-regulation
AGC_GRK_BARK_GRK2_ST	P08172	CHRM2	P25098	GRK2	S294	M296I	296	Missense	proximal	2	no	138.400	130.982	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	128.034	Down-regulation
AGC_GRK_BARK_GRK2_ST	P08172	CHRM2	P25098	GRK2	S294	V292L	292	Missense	proximal	-2	no	138.400	137.671	EPSD;PhosphoSitePlus	TCGA;ICGC	128.034	Down-regulation
AGC_GRK_BARK_GRK2_ST	P08172	CHRM2	P25098	GRK2	S294	A291S	291	Missense	distal	-3	no	138.400	141.030	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	128.034	Up-regulation
AGC_GRK_BARK_GRK2_ST	P08172	CHRM2	P25098	GRK2	S294	S288L	288	Missense	distal	-6	no	138.400	131.844	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	128.034	Down-regulation
AGC_GRK_BARK_GRK2_ST	P08172	CHRM2	P25098	GRK2	S294	D298N	298	Missense	distal	4	no	138.400	136.317	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	128.034	Down-regulation
AGC_GRK_BARK_GRK2_ST	P08172	CHRM2	P25098	GRK2	S294	A291D	291	Missense	distal	-3	no	138.400	154.656	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	128.034	Up-regulation
AGC_GRK_BARK_GRK2_ST	P08172	CHRM2	P25098	GRK2	T302	M296I	296	Missense	distal	-6	no	163.423	151.080	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	128.034	Down-regulation
AGC_GRK_BARK_GRK2_ST	P08172	CHRM2	P25098	GRK2	T302	T307K	307	Missense	distal	5	no	163.423	163.690	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	128.034	Up-regulation
AGC_GRK_BARK_GRK2_ST	P08172	CHRM2	P25098	GRK2	T302	D298N	298	Missense	distal	-4	no	163.423	151.568	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	128.034	Down-regulation
AGC_GRK_BARK_GRK2_ST	P08172	CHRM2	P25098	GRK2	T302	V308I	308	Missense	distal	6	no	163.423	161.616	EPSD;PhosphoSitePlus	TCGA;ICGC	128.034	Down-regulation
AGC_GRK_BARK_GRK2_ST	P08172	CHRM2	P25098	GRK2	T307	S311T	311	Missense	distal	4	no	163.633	158.316	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	128.034	Down-regulation
AGC_GRK_BARK_GRK2_ST	P08172	CHRM2	P25098	GRK2	T307	G313V	313	Missense	distal	6	no	163.633	165.169	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	128.034	Up-regulation
AGC_GRK_BARK_GRK2_ST	P08172	CHRM2	P25098	GRK2	T307	T307K	307	Missense	central	0	yes	163.633	0.000	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	128.034	Loss
AGC_GRK_BARK_GRK2_ST	P08172	CHRM2	P25098	GRK2	T307	G313C	313	Missense	distal	6	no	163.633	166.846	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	128.034	Up-regulation
AGC_GRK_BARK_GRK2_ST	P08172	CHRM2	P25098	GRK2	T307	L312M	312	Missense	distal	5	no	163.633	166.364	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	128.034	Up-regulation
AGC_GRK_BARK_GRK2_ST	P08172	CHRM2	P25098	GRK2	T307	V308I	308	Missense	proximal	1	no	163.633	143.838	EPSD;PhosphoSitePlus	TCGA;ICGC	128.034	Down-regulation
AGC_GRK_BARK_GRK2_ST	P08172	CHRM2	P25098	GRK2	S309	S311T	311	Missense	proximal	2	no	154.235	151.473	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	128.034	Down-regulation
AGC_GRK_BARK_GRK2_ST	P08172	CHRM2	P25098	GRK2	S309	G313V	313	Missense	distal	4	no	154.235	158.944	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	128.034	Up-regulation
AGC_GRK_BARK_GRK2_ST	P08172	CHRM2	P25098	GRK2	S309	T307K	307	Missense	proximal	-2	no	154.235	153.880	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	128.034	Down-regulation
AGC_GRK_BARK_GRK2_ST	P08172	CHRM2	P25098	GRK2	S309	G313C	313	Missense	distal	4	no	154.235	156.718	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	128.034	Up-regulation
AGC_GRK_BARK_GRK2_ST	P08172	CHRM2	P25098	GRK2	S309	L312M	312	Missense	distal	3	no	154.235	153.348	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	128.034	Down-regulation
AGC_GRK_BARK_GRK2_ST	P08172	CHRM2	P25098	GRK2	S309	S315F	315	Missense	distal	6	no	154.235	152.010	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	128.034	Down-regulation
AGC_GRK_BARK_GRK2_ST	P08172	CHRM2	P25098	GRK2	S309	V308I	308	Missense	proximal	-1	no	154.235	141.516	EPSD;PhosphoSitePlus	TCGA;ICGC	128.034	Down-regulation
AGC_GRK_BARK_GRK2_ST	P08172	CHRM2	P25098	GRK2	T310	S311T	311	Missense	proximal	1	no	146.879	138.880	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	128.034	Down-regulation
AGC_GRK_BARK_GRK2_ST	P08172	CHRM2	P25098	GRK2	T310	D317Y	317	Missense	distal	7	no	146.879	147.526	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	128.034	Up-regulation
AGC_GRK_BARK_GRK2_ST	P08172	CHRM2	P25098	GRK2	T310	G313V	313	Missense	distal	3	no	146.879	149.951	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	128.034	Up-regulation
AGC_GRK_BARK_GRK2_ST	P08172	CHRM2	P25098	GRK2	T310	T307K	307	Missense	distal	-3	no	146.879	128.452	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	128.034	Down-regulation
AGC_GRK_BARK_GRK2_ST	P08172	CHRM2	P25098	GRK2	T310	G313C	313	Missense	distal	3	no	146.879	149.326	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	128.034	Up-regulation
AGC_GRK_BARK_GRK2_ST	P08172	CHRM2	P25098	GRK2	T310	L312M	312	Missense	proximal	2	no	146.879	149.900	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	128.034	Up-regulation
AGC_GRK_BARK_GRK2_ST	P08172	CHRM2	P25098	GRK2	T310	S315F	315	Missense	distal	5	no	146.879	141.365	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	128.034	Down-regulation
AGC_GRK_BARK_GRK2_ST	P08172	CHRM2	P25098	GRK2	T310	V308I	308	Missense	proximal	-2	no	146.879	138.373	EPSD;PhosphoSitePlus	TCGA;ICGC	128.034	Down-regulation
AGC_GRK_BARK_GRK2_ST	P08172	CHRM2	P25098	GRK2	S311	D317Y	317	Missense	distal	6	no	143.703	143.825	PhosphoSitePlus;EPSD	TCGA;ICGC;COSMIC	128.034	Up-regulation
AGC_GRK_BARK_GRK2_ST	P08172	CHRM2	P25098	GRK2	S311	E318G	318	Missense	distal	7	no	143.703	143.811	PhosphoSitePlus;EPSD	TCGA;ICGC;COSMIC	128.034	Up-regulation
AGC_GRK_BARK_GRK2_ST	P08172	CHRM2	P25098	GRK2	S311	E318K	318	Missense	distal	7	no	143.703	143.543	PhosphoSitePlus;EPSD	TCGA;ICGC;COSMIC	128.034	Down-regulation
AGC_GRK_BARK_GRK2_ST	P08172	CHRM2	P25098	GRK2	S311	G313V	313	Missense	proximal	2	no	143.703	145.192	PhosphoSitePlus;EPSD	TCGA;ICGC;COSMIC	128.034	Up-regulation
AGC_GRK_BARK_GRK2_ST	P08172	CHRM2	P25098	GRK2	S311	T307K	307	Missense	distal	-4	no	143.703	137.644	PhosphoSitePlus;EPSD	TCGA;ICGC;COSMIC	128.034	Down-regulation
AGC_GRK_BARK_GRK2_ST	P08172	CHRM2	P25098	GRK2	S311	G313C	313	Missense	proximal	2	no	143.703	141.398	PhosphoSitePlus;EPSD	TCGA;ICGC;COSMIC	128.034	Down-regulation
AGC_GRK_BARK_GRK2_ST	P08172	CHRM2	P25098	GRK2	S311	L312M	312	Missense	proximal	1	no	143.703	144.916	PhosphoSitePlus;EPSD	TCGA;ICGC;COSMIC	128.034	Up-regulation
AGC_GRK_BARK_GRK2_ST	P08172	CHRM2	P25098	GRK2	S311	S315F	315	Missense	distal	4	no	143.703	134.716	PhosphoSitePlus;EPSD	TCGA;ICGC;COSMIC	128.034	Down-regulation
AGC_GRK_BARK_GRK2_ST	P08172	CHRM2	P25098	GRK2	S311	V308I	308	Missense	distal	-3	no	143.703	127.965	PhosphoSitePlus;EPSD	TCGA;ICGC	128.034	Loss
AGC_GRK_BARK_GRK2_ST	P08172	CHRM2	P25098	GRK2	S311	E318D	318	Missense	distal	7	no	143.703	143.397	PhosphoSitePlus;EPSD	TCGA;ICGC;COSMIC	128.034	Down-regulation
AGC_GRK_BARK_GRK2_ST	P35367	HRH1	P25098	GRK2	S275	T279S	279	Missense	distal	4	no	124.894	130.211	EPSD	TCGA;ICGC;COSMIC	128.034	Gain
AGC_GRK_BARK_GRK2_ST	P35367	HRH1	P25098	GRK2	S275	P276S	276	Missense	proximal	1	no	124.894	132.055	EPSD	TCGA;ICGC;COSMIC	128.034	Gain
AGC_GRK_BARK_GRK2_ST	P35367	HRH1	P25098	GRK2	S277	T279S	279	Missense	proximal	2	no	132.643	135.405	EPSD	TCGA;ICGC;COSMIC	128.034	Up-regulation
AGC_GRK_BARK_GRK2_ST	P35367	HRH1	P25098	GRK2	S277	P276S	276	Missense	proximal	-1	no	132.643	128.705	EPSD	TCGA;ICGC;COSMIC	128.034	Down-regulation
AGC_GRK_BARK_GRK2_ST	P35367	HRH1	P25098	GRK2	S277	P280S	280	Missense	distal	3	no	132.643	129.645	EPSD	TCGA;ICGC;COSMIC	128.034	Down-regulation
AGC_GRK_BARK_GRK2_ST	P35367	HRH1	P25098	GRK2	S277	P280L	280	Missense	distal	3	no	132.643	132.087	EPSD	TCGA;ICGC;COSMIC	128.034	Down-regulation
AGC_GRK_BARK_GRK2_ST	P35367	HRH1	P25098	GRK2	S396	S396L	396	Missense	central	0	yes	137.287	0.000	EPSD	TCGA;ICGC;COSMIC	128.034	Loss
AGC_GRK_BARK_GRK2_ST	P35367	HRH1	P25098	GRK2	S396	R395H	395	Missense	proximal	-1	no	137.287	140.922	EPSD	TCGA;ICGC	128.034	Up-regulation
AGC_GRK_BARK_GRK2_ST	P35367	HRH1	P25098	GRK2	S398	S396L	396	Missense	proximal	-2	no	138.286	130.090	PhosphoSitePlus	TCGA;ICGC;COSMIC	128.034	Down-regulation
AGC_GRK_BARK_GRK2_ST	P35367	HRH1	P25098	GRK2	S398	R395H	395	Missense	distal	-3	no	138.286	133.682	PhosphoSitePlus	TCGA;ICGC	128.034	Down-regulation
AGC_GRK_BARK_GRK2_ST	P21731	TBXA2R	P25098	GRK2	S324	R318H	318	Missense	distal	-6	no	131.962	129.982	EPSD	TCGA	128.034	Down-regulation
AGC_GRK_BARK_GRK2_ST	P21731	TBXA2R	P25098	GRK2	S324	R326Q	326	Missense	proximal	2	no	131.962	131.797	EPSD	TCGA;ICGC;COSMIC	128.034	Down-regulation
AGC_GRK_BARK_GRK2_ST	P21731	TBXA2R	P25098	GRK2	S329	R326Q	326	Missense	distal	-3	no	136.048	137.178	EPSD	TCGA;ICGC;COSMIC	128.034	Up-regulation
AGC_GRK_BARK_GRK2_ST	P21731	TBXA2R	P25098	GRK2	S331	R326Q	326	Missense	distal	-5	no	159.561	155.202	EPSD	TCGA;ICGC;COSMIC	128.034	Down-regulation
AGC_GRK_BARK_GRK2_ST	O95398	RAPGEF3	P25098	GRK2	S209	G212E	212	Missense	distal	3	no	136.662	140.303	EPSD	TCGA;ICGC;COSMIC	128.034	Up-regulation
AGC_GRK_BARK_GRK2_ST	O95398	RAPGEF3	P25098	GRK2	S209	E203K	203	Missense	distal	-6	no	136.662	131.964	EPSD	TCGA;ICGC;COSMIC	128.034	Down-regulation
AGC_GRK_BARK_GRK2_ST	O95398	RAPGEF3	P25098	GRK2	S209	A215T	215	Missense	distal	6	no	136.662	137.451	EPSD	TCGA;ICGC;COSMIC	128.034	Up-regulation
AGC_GRK_BARK_GRK2_ST	O95398	RAPGEF3	P25098	GRK2	S370	Q371E	371	Missense	proximal	1	no	138.681	144.660	EPSD	TCGA;ICGC;COSMIC	128.034	Up-regulation
AGC_GRK_BARK_GRK2_ST	O95398	RAPGEF3	P25098	GRK2	S370	G374D	374	Missense	distal	4	no	138.681	140.854	EPSD	TCGA;ICGC;COSMIC	128.034	Up-regulation
AGC_GRK_BARK_GRK2_ST	O95398	RAPGEF3	P25098	GRK2	S370	A373T	373	Missense	distal	3	no	138.681	140.219	EPSD	TCGA;ICGC;COSMIC	128.034	Up-regulation
AGC_GRK_BARK_GRK2_ST	O95398	RAPGEF3	P25098	GRK2	S370	P375S	375	Missense	distal	5	no	138.681	140.876	EPSD	TCGA;ICGC;COSMIC	128.034	Up-regulation
AGC_GRK_BARK_GRK2_ST	O95398	RAPGEF3	P25098	GRK2	T380	G374D	374	Missense	distal	-6	no	128.646	135.523	EPSD	TCGA;ICGC;COSMIC	128.034	Up-regulation
AGC_GRK_BARK_GRK2_ST	O95398	RAPGEF3	P25098	GRK2	T380	A373T	373	Missense	distal	-7	no	128.646	128.623	EPSD	TCGA;ICGC;COSMIC	128.034	Down-regulation
AGC_GRK_BARK_GRK2_ST	O95398	RAPGEF3	P25098	GRK2	T380	P375S	375	Missense	distal	-5	no	128.646	133.953	EPSD	TCGA;ICGC;COSMIC	128.034	Up-regulation
AGC_GRK_BARK_GRK2_ST	O95398	RAPGEF3	P25098	GRK2	S915	L917I	917	Missense	proximal	2	no	141.113	136.715	EPSD	TCGA;ICGC	128.034	Down-regulation
AGC_GRK_BARK_GRK2_ST	O95398	RAPGEF3	P25098	GRK2	S915	R916H	916	Missense	proximal	1	no	141.113	144.672	EPSD	TCGA;ICGC;COSMIC	128.034	Up-regulation
AGC_GRK_BARK_GRK2_ST	O95398	RAPGEF3	P25098	GRK2	S915	L921P	921	Missense	distal	6	no	141.113	143.344	EPSD	TCGA;ICGC;COSMIC	128.034	Up-regulation
AGC_GRK_BARK_GRK2_ST	O95398	RAPGEF3	P25098	GRK2	S918	L917I	917	Missense	proximal	-1	no	129.954	124.355	EPSD	TCGA;ICGC	128.034	Loss
AGC_GRK_BARK_GRK2_ST	O95398	RAPGEF3	P25098	GRK2	S918	R916H	916	Missense	proximal	-2	no	129.954	128.461	EPSD	TCGA;ICGC;COSMIC	128.034	Down-regulation
AGC_GRK_BARK_GRK2_ST	O95398	RAPGEF3	P25098	GRK2	S918	L921P	921	Missense	distal	3	no	129.954	130.510	EPSD	TCGA;ICGC;COSMIC	128.034	Up-regulation
AGC_GRK_BARK_GRK2_ST	P09497	CLTB	P25098	GRK2	T190	K184N	184	Missense	distal	-6	no	137.183	142.394	EPSD	TCGA;COSMIC	128.034	Up-regulation
AGC_GRK_BARK_GRK2_ST	P09497	CLTB	P25098	GRK2	T190	E185D	185	Missense	distal	-5	no	137.183	136.258	EPSD	TCGA;ICGC;COSMIC	128.034	Down-regulation
AGC_GRK_BARK_GRK2_ST	P09497	CLTB	P25098	GRK2	S205	K210E	210	Missense	distal	5	no	173.206	177.775	PhosphoSitePlus	TCGA;COSMIC	128.034	Up-regulation
AGC_GRK_BARK_GRK2_ST	P09497	CLTB	P25098	GRK2	S213	R216C	216	Missense	distal	3	no	156.722	157.262	EPSD	TCGA;ICGC;COSMIC	128.034	Up-regulation
AGC_GRK_BARK_GRK2_ST	P09497	CLTB	P25098	GRK2	S213	L219P	219	Missense	distal	6	no	156.722	158.953	EPSD	TCGA;ICGC;COSMIC	128.034	Up-regulation
AGC_GRK_BARK_GRK2_ST	P09497	CLTB	P25098	GRK2	S213	K210E	210	Missense	distal	-3	no	156.722	178.152	EPSD	TCGA;COSMIC	128.034	Up-regulation
AGC_GRK_BARK_GRK2_ST	P09497	CLTB	P25098	GRK2	S217	R216C	216	Missense	proximal	-1	no	161.415	161.121	EPSD	TCGA;ICGC;COSMIC	128.034	Down-regulation
AGC_GRK_BARK_GRK2_ST	P09497	CLTB	P25098	GRK2	S217	L219P	219	Missense	proximal	2	no	161.415	166.359	EPSD	TCGA;ICGC;COSMIC	128.034	Up-regulation
AGC_GRK_BARK_GRK2_ST	P09497	CLTB	P25098	GRK2	S217	Q224L	224	Missense	distal	7	no	161.415	162.445	EPSD	TCGA;COSMIC	128.034	Up-regulation
AGC_GRK_BARK_GRK2_ST	P09497	CLTB	P25098	GRK2	S217	K210E	210	Missense	distal	-7	no	161.415	161.026	EPSD	TCGA;COSMIC	128.034	Down-regulation
AGC_GRK_BARK_GRK2_ST	P09497	CLTB	P25098	GRK2	S221	L219P	219	Missense	proximal	-2	no	127.893	131.923	EPSD	TCGA;ICGC;COSMIC	128.034	Gain
AGC_GRK_BARK_GRK2_ST	P09497	CLTB	P25098	GRK2	S221	Q224L	224	Missense	distal	3	no	127.893	130.681	EPSD	TCGA;COSMIC	128.034	Gain
AGC_GRK_BARK_GRK2_ST	P09497	CLTB	P25098	GRK2	T225	L219P	219	Missense	distal	-6	no	137.440	137.828	EPSD	TCGA;ICGC;COSMIC	128.034	Up-regulation
AGC_GRK_BARK_GRK2_ST	P09497	CLTB	P25098	GRK2	T225	Q224L	224	Missense	proximal	-1	no	137.440	131.947	EPSD	TCGA;COSMIC	128.034	Down-regulation
AGC_GRK_BARK_GRK2_ST	P09497	CLTB	P25098	GRK2	S228	Q224L	224	Missense	distal	-4	no	150.885	151.521	EPSD	TCGA;COSMIC	128.034	Up-regulation
AGC_GRK_BARK_GRK2_ST	Q16539	MAPK14	P25098	GRK2	T123	D124N	124	Missense	proximal	1	no	134.208	132.774	PhosphoSitePlus	TCGA;ICGC;COSMIC	128.034	Down-regulation
AGC_GRK_BARK_GRK2_ST	Q16539	MAPK14	P25098	GRK2	S326	D324A	324	Missense	proximal	-2	no	133.019	117.485	EPSD	TCGA;COSMIC	128.034	Loss
AGC_GRK_BARK_GRK2_ST	P26038	MSN	P25098	GRK2	S90	S90Y	90	Missense	central	0	yes	131.598	0.000	EPSD	TCGA;ICGC;COSMIC	128.034	Loss
AGC_GRK_BARK_GRK2_ST	P26038	MSN	P25098	GRK2	S90	D88H	88	Missense	proximal	-2	no	131.598	119.889	EPSD	TCGA;ICGC;COSMIC	128.034	Loss
AGC_GRK_BARK_GRK2_ST	P26038	MSN	P25098	GRK2	S90	P86S	86	Missense	distal	-4	no	131.598	141.183	EPSD	TCGA;ICGC;COSMIC	128.034	Up-regulation
AGC_GRK_BARK_GRK2_ST	P26038	MSN	P25098	GRK2	S207	I208M	208	Missense	proximal	1	no	133.374	154.762	EPSD	TCGA;ICGC;COSMIC	128.034	Up-regulation
AGC_GRK_BARK_GRK2_ST	P26038	MSN	P25098	GRK2	S207	Y201C	201	Missense	distal	-6	no	133.374	126.946	EPSD	TCGA	128.034	Loss
AGC_GRK_BARK_GRK2_ST	P26038	MSN	P25098	GRK2	S207	S207N	207	Missense	central	0	yes	133.374	0.000	EPSD	TCGA;ICGC;COSMIC	128.034	Loss
AGC_GRK_BARK_GRK2_ST	P26038	MSN	P25098	GRK2	S207	Y205D	205	Missense	proximal	-2	no	133.374	135.065	EPSD	TCGA;ICGC	128.034	Up-regulation
AGC_GRK_BARK_GRK2_ST	P26038	MSN	P25098	GRK2	S384	A386T	386	Missense	proximal	2	no	139.602	139.949	EPSD	TCGA;ICGC;COSMIC	128.034	Up-regulation
AGC_GRK_BARK_GRK2_ST	P26038	MSN	P25098	GRK2	S384	R381H	381	Missense	distal	-3	no	139.602	134.997	EPSD	TCGA;ICGC;COSMIC	128.034	Down-regulation
AGC_GRK_BARK_GRK2_ST	P26038	MSN	P25098	GRK2	S384	K388T	388	Missense	distal	4	no	139.602	140.196	EPSD	TCGA;ICGC	128.034	Up-regulation
AGC_GRK_BARK_GRK2_ST	P26038	MSN	P25098	GRK2	S384	S384N	384	Missense	central	0	yes	139.602	0.000	EPSD	TCGA;ICGC	128.034	Loss
AGC_GRK_BARK_GRK2_ST	P26038	MSN	P25098	GRK2	T413	Q416E	416	Missense	distal	3	no	124.677	131.146	EPSD	TCGA;ICGC;COSMIC	128.034	Gain
AGC_GRK_BARK_GRK2_ST	P26038	MSN	P25098	GRK2	T510	R503C	503	Missense	distal	-7	no	128.394	127.085	EPSD	TCGA;ICGC;COSMIC	128.034	Loss
AGC_GRK_BARK_GRK2_ST	P26038	MSN	P25098	GRK2	T510	R508C	508	Missense	proximal	-2	no	128.394	120.858	EPSD	TCGA;ICGC;COSMIC	128.034	Loss
AGC_GRK_BARK_GRK2_ST	P26038	MSN	P25098	GRK2	T510	R503H	503	Missense	distal	-7	no	128.394	122.804	EPSD	TCGA;ICGC;COSMIC	128.034	Loss
AGC_GRK_BARK_GRK2_ST	P26038	MSN	P25098	GRK2	T510	E505K	505	Missense	distal	-5	no	128.394	124.066	EPSD	TCGA;ICGC;COSMIC	128.034	Loss
AGC_GRK_BARK_GRK2_ST	P26038	MSN	P25098	GRK2	T558	R560C	560	Missense	proximal	2	no	164.331	161.485	PhosphoSitePlus	TCGA;ICGC;COSMIC	128.034	Down-regulation
AGC_GRK_BARK_GRK2_ST	P26038	MSN	P25098	GRK2	T558	Q561H	561	Missense	distal	3	no	164.331	168.296	PhosphoSitePlus	TCGA;ICGC;COSMIC	128.034	Up-regulation
AGC_GRK_BARK_GRK2_ST	P26038	MSN	P25098	GRK2	T558	K557N	557	Missense	proximal	-1	no	164.331	177.065	PhosphoSitePlus	TCGA;ICGC	128.034	Up-regulation
AGC_GRK_BARK_GRK2_ST	P26038	MSN	P25098	GRK2	T558	R553Q	553	Missense	distal	-5	no	164.331	159.972	PhosphoSitePlus	TCGA;ICGC	128.034	Down-regulation
AGC_GRK_BARK_GRK2_ST	P26038	MSN	P25098	GRK2	T567	R560C	560	Missense	distal	-7	no	144.054	142.745	EPSD	TCGA;ICGC;COSMIC	128.034	Down-regulation
AGC_GRK_BARK_GRK2_ST	P26038	MSN	P25098	GRK2	T567	Q561H	561	Missense	distal	-6	no	144.054	137.172	EPSD	TCGA;ICGC;COSMIC	128.034	Down-regulation
AGC_GRK_BARK_GRK2_ST	P26038	MSN	P25098	GRK2	T567	E573K	573	Missense	distal	6	no	144.054	140.220	EPSD	TCGA;ICGC;COSMIC	128.034	Down-regulation
AGC_GRK_BARK_GRK2_ST	P26038	MSN	P25098	GRK2	S576	E573K	573	Missense	distal	-3	no	157.522	136.092	EPSD	TCGA;ICGC;COSMIC	128.034	Down-regulation
AGC_GRK_BARK_GRK2_ST	Q9Y2W7	KCNIP3	P25098	GRK2	S95	T89S	89	Missense	distal	-6	no	135.418	136.347	PhosphoSitePlus	TCGA;ICGC;COSMIC	128.034	Up-regulation
AGC_GRK_BARK_GRK2_ST	Q9Y2W7	KCNIP3	P25098	GRK2	S95	E92K	92	Missense	distal	-3	no	135.418	113.988	PhosphoSitePlus	TCGA;ICGC;COSMIC	128.034	Loss
AGC_GRK_BARK_GRK2_ST	Q9Y2W7	KCNIP3	P25098	GRK2	S95	K91E	91	Missense	distal	-4	no	135.418	140.510	PhosphoSitePlus	TCGA;ICGC;COSMIC	128.034	Up-regulation
AGC_GRK_BARK_GRK2_ST	Q96A54	ADIPOR1	P25098	GRK2	T24	A22V	22	Missense	proximal	-2	no	149.710	153.866	PhosphoSitePlus;EPSD	TCGA;ICGC;COSMIC	128.034	Up-regulation
AGC_GRK_BARK_GRK2_ST	Q96A54	ADIPOR1	P25098	GRK2	T24	L30P	30	Missense	distal	6	no	149.710	151.941	PhosphoSitePlus;EPSD	TCGA;ICGC;COSMIC	128.034	Up-regulation
AGC_GRK_BARK_GRK2_ST	Q96A54	ADIPOR1	P25098	GRK2	T53	E60K	60	Missense	distal	7	no	143.691	143.531	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	128.034	Down-regulation
AGC_GRK_BARK_GRK2_ST	Q96A54	ADIPOR1	P25098	GRK2	T53	V56A	56	Missense	distal	3	no	143.691	136.822	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	128.034	Down-regulation
AGC_GRK_BARK_GRK2_ST	Q96A54	ADIPOR1	P25098	GRK2	T53	E50K	50	Missense	distal	-3	no	143.691	122.261	EPSD;PhosphoSitePlus	TCGA;ICGC	128.034	Loss
AGC_GRK_BARK_GRK2_ST	Q15796	SMAD2	P25098	GRK2	S118	G122V	122	Missense	distal	4	no	126.519	131.229	EPSD	TCGA;ICGC;COSMIC	128.034	Gain
AGC_GRK_BARK_GRK2_ST	Q15796	SMAD2	P25098	GRK2	T197	H198Y	198	Missense	proximal	1	no	143.095	132.484	PhosphoSitePlus	TCGA;ICGC;COSMIC	128.034	Down-regulation
AGC_GRK_BARK_GRK2_ST	Q15796	SMAD2	P25098	GRK2	S351	F356C	356	Missense	distal	5	no	127.717	129.528	EPSD	TCGA;ICGC;COSMIC	128.034	Gain
AGC_GRK_BARK_GRK2_ST	Q15796	SMAD2	P25098	GRK2	T454	K451E	451	Missense	distal	-3	no	107.678	129.108	EPSD	TCGA;ICGC;COSMIC	128.034	Gain
AGC_GRK_BARK_GRK2_ST	Q15796	SMAD2	P25098	GRK2	S460	G457A	457	Missense	distal	-3	no	143.401	141.261	EPSD	TCGA;ICGC;COSMIC	128.034	Down-regulation
AGC_GRK_BARK_GRK2_ST	P08069	IGF1R	P25098	GRK2	S609	V610I	610	Missense	proximal	1	no	129.653	109.857	EPSD	TCGA;ICGC;COSMIC	128.034	Loss
AGC_GRK_BARK_GRK2_ST	P08069	IGF1R	P25098	GRK2	S609	R605L	605	Missense	distal	-4	no	129.653	132.084	EPSD	TCGA;ICGC;COSMIC	128.034	Up-regulation
AGC_GRK_BARK_GRK2_ST	P08069	IGF1R	P25098	GRK2	S609	P611S	611	Missense	proximal	2	no	129.653	129.376	EPSD	TCGA;ICGC;COSMIC	128.034	Down-regulation
AGC_GRK_BARK_GRK2_ST	P08069	IGF1R	P25098	GRK2	S609	R605C	605	Missense	distal	-4	no	129.653	133.896	EPSD	TCGA;ICGC;COSMIC	128.034	Up-regulation
AGC_GRK_BARK_GRK2_ST	P08069	IGF1R	P25098	GRK2	S609	A608D	608	Missense	proximal	-1	no	129.653	146.168	EPSD	TCGA;ICGC;COSMIC	128.034	Up-regulation
AGC_GRK_BARK_GRK2_ST	P08069	IGF1R	P25098	GRK2	S752	R753Q	753	Missense	proximal	1	no	142.535	141.063	EPSD	TCGA;ICGC;COSMIC	128.034	Down-regulation
AGC_GRK_BARK_GRK2_ST	P08069	IGF1R	P25098	GRK2	T1163	T1157M	1157	Missense	distal	-6	no	123.156	130.312	EPSD	TCGA	128.034	Gain
AGC_GRK_BARK_GRK2_ST	P08069	IGF1R	P25098	GRK2	S1339	R1337H	1337	Missense	proximal	-2	no	131.255	129.762	EPSD	TCGA;COSMIC	128.034	Down-regulation
AGC_GRK_BARK_GRK2_ST	P08069	IGF1R	P25098	GRK2	S1364	T1366A	1366	Missense	proximal	2	no	145.142	144.795	EPSD	TCGA	128.034	Down-regulation
AGC_GRK_BARK_GRK2_ST	P08069	IGF1R	P25098	GRK2	S1365	T1366A	1366	Missense	proximal	1	no	138.645	136.513	EPSD	TCGA	128.034	Down-regulation
AGC_GRK_BARK_GRK2_ST	P08069	IGF1R	P25098	GRK2	T1366	T1366A	1366	Missense	central	0	yes	136.759	0.000	EPSD	TCGA	128.034	Loss
AGC_GRK_BARK_GRK2_ST	O60353	FZD6	P25098	GRK2	S620	S626C	626	Missense	distal	6	no	126.488	130.486	EPSD	TCGA;ICGC;COSMIC	128.034	Gain
AGC_GRK_BARK_GRK2_ST	O60353	FZD6	P25098	GRK2	S620	A622V	622	Missense	proximal	2	no	126.488	133.411	EPSD	TCGA;ICGC;COSMIC	128.034	Gain
AGC_GRK_BARK_GRK2_ST	O60353	FZD6	P25098	GRK2	S620	I625V	625	Missense	distal	5	no	126.488	129.118	EPSD	TCGA;ICGC	128.034	Gain
AGC_GRK_BARK_GRK2_ST	O60353	FZD6	P25098	GRK2	S645	R647W	647	Missense	proximal	2	no	141.936	132.022	EPSD	TCGA;ICGC;COSMIC	128.034	Down-regulation
AGC_GRK_BARK_GRK2_ST	O60353	FZD6	P25098	GRK2	S648	R647W	647	Missense	proximal	-1	no	131.612	119.453	PhosphoSitePlus	TCGA;ICGC;COSMIC	128.034	Loss
AGC_GRK_BARK_GRK2_ST	O60353	FZD6	P25098	GRK2	S673	L669S	669	Missense	distal	-4	no	152.074	158.032	EPSD	TCGA;ICGC;COSMIC	128.034	Up-regulation
AGC_GRK_BARK_GRK2_ST	O60353	FZD6	P25098	GRK2	S673	S678N	678	Missense	distal	5	no	152.074	147.126	EPSD	TCGA	128.034	Down-regulation
AGC_GRK_BARK_GRK2_ST	O60353	FZD6	P25098	GRK2	S675	L669S	669	Missense	distal	-6	no	132.040	138.595	EPSD	TCGA;ICGC;COSMIC	128.034	Up-regulation
AGC_GRK_BARK_GRK2_ST	O60353	FZD6	P25098	GRK2	S675	S678N	678	Missense	distal	3	no	132.040	133.407	EPSD	TCGA	128.034	Up-regulation
AGC_GRK_BARK_GRK2_ST	O60353	FZD6	P25098	GRK2	S678	S678N	678	Missense	central	0	yes	170.997	0.000	EPSD	TCGA	128.034	Loss
AGC_GRK_BARK_GRK2_ST	O60353	FZD6	P25098	GRK2	S679	S678N	678	Missense	proximal	-1	no	161.961	162.162	EPSD	TCGA	128.034	Up-regulation
AGC_GRK_BARK_GRK2_ST	O60353	FZD6	P25098	GRK2	T684	S678N	678	Missense	distal	-6	no	132.339	134.992	EPSD	TCGA	128.034	Up-regulation
AGC_GRK_BARK_GRK2_ST	O60353	FZD6	P25098	GRK2	T684	P690S	690	Missense	distal	6	no	132.339	131.603	EPSD	TCGA;ICGC;COSMIC	128.034	Down-regulation
AGC_GRK_BARK_GRK2_ST	O60353	FZD6	P25098	GRK2	T684	H689R	689	Missense	distal	5	no	132.339	133.029	EPSD	TCGA;ICGC;COSMIC	128.034	Up-regulation
AGC_GRK_BARK_GRK2_ST	P37840	SNCA	P25098	GRK2	S129	D135Y	135	Missense	distal	6	no	184.693	184.815	PhosphoSitePlus	TCGA;ICGC;COSMIC	128.034	Up-regulation
AGC_GRK_BARK_GRK2_ST	P37840	SNCA	P25098	GRK2	S129	S129F	129	Missense	central	0	yes	184.693	0.000	PhosphoSitePlus	TCGA;ICGC;COSMIC	128.034	Loss
STE_STE11_MEKK2_MAP3K2_ST	P35222	CTNNB1	Q9Y2U5	MAP3K2	T201	A197S	197	Missense	distal	-4	no	2.215	2.155	EPSD	TCGA;COSMIC	2.079	Down-regulation
STE_STE11_MEKK2_MAP3K2_ST	P35222	CTNNB1	Q9Y2U5	MAP3K2	T201	V199I	199	Missense	proximal	-2	no	2.215	2.205	EPSD	TCGA;COSMIC	2.079	Down-regulation
STE_STE11_MEKK2_MAP3K2_ST	P35222	CTNNB1	Q9Y2U5	MAP3K2	S250	I256M	256	Missense	distal	6	no	2.008	2.134	EPSD	TCGA;COSMIC	2.079	Gain
STE_STE11_MEKK2_MAP3K2_ST	P35222	CTNNB1	Q9Y2U5	MAP3K2	S250	I256T	256	Missense	distal	6	no	2.008	2.281	EPSD	TCGA;COSMIC	2.079	Gain
STE_STE11_MEKK2_MAP3K2_ST	P35222	CTNNB1	Q9Y2U5	MAP3K2	S675	S681F	681	Missense	distal	6	no	4.783	4.531	PhosphoSitePlus	TCGA	2.079	Down-regulation
STE_STE11_MEKK2_MAP3K2_ST	Q14653	IRF3	Q9Y2U5	MAP3K2	S173	P170S	170	Missense	distal	-3	no	5.380	4.989	PhosphoSitePlus	TCGA;COSMIC;CCLE	2.079	Down-regulation
STE_STE7_MEK1_MAP2K2_ST	P27361	MAPK3	P36507	MAP2K2	T17	R16I	16	Missense	proximal	-1	no	1.756	2.166	EPSD	TCGA;ICGC;COSMIC	1.900	Gain
STE_STE7_MEK1_MAP2K2_ST	P05787	KRT8	P36507	MAP2K2	T187	E192K	192	Missense	distal	5	no	2.105	2.187	EPSD	TCGA;COSMIC	1.900	Up-regulation
TK_Jak_JAK3_Y	O14939	PLD2	P52333	JAK3	Y296	R300Q	300	Missense	distal	4	no	96.737	101.089	EPSD	TCGA;ICGC;COSMIC	65.077	Up-regulation
TK_Jak_JAK3_Y	O14939	PLD2	P52333	JAK3	Y415	A419V	419	Missense	distal	4	no	105.166	98.870	PhosphoSitePlus	TCGA;ICGC;COSMIC	65.077	Down-regulation
TK_Jak_JAK3_Y	Q15910	EZH2	P52333	JAK3	Y244	E249K	249	Missense	distal	5	no	87.814	87.916	PhosphoSitePlus	TCGA;COSMIC	65.077	Up-regulation
TK_Jak_JAK3_Y	Q15910	EZH2	P52333	JAK3	Y244	A237S	237	Missense	distal	-7	no	87.814	88.387	PhosphoSitePlus	TCGA	65.077	Up-regulation
TK_Jak_JAK3_Y	Q15910	EZH2	P52333	JAK3	Y244	K241Q	241	Missense	distal	-3	no	87.814	88.288	PhosphoSitePlus	TCGA;COSMIC	65.077	Up-regulation
TK_Jak_JAK3_Y	P52333	JAK3	P52333	JAK3	Y506	Q507L	507	Missense	proximal	1	no	88.067	91.889	EPSD	TCGA;ICGC;COSMIC	65.077	Up-regulation
TK_Jak_JAK3_Y	P52333	JAK3	P52333	JAK3	Y506	Q507R	507	Missense	proximal	1	no	88.067	88.789	EPSD	TCGA;ICGC;COSMIC	65.077	Up-regulation
TK_Jak_JAK3_Y	P52333	JAK3	P52333	JAK3	Y506	Q507H	507	Missense	proximal	1	no	88.067	88.435	EPSD	TCGA;ICGC;COSMIC	65.077	Up-regulation
TK_Jak_JAK3_Y	P52333	JAK3	P52333	JAK3	Y785	S789L	789	Missense	distal	4	no	111.759	88.935	PhosphoSitePlus;EPSD	TCGA;ICGC;COSMIC;GDSC;CCLE	65.077	Down-regulation
TK_Jak_JAK3_Y	P52333	JAK3	P52333	JAK3	Y904	R899W	899	Missense	distal	-5	no	108.604	110.995	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	65.077	Up-regulation
TK_Jak_JAK3_Y	P52333	JAK3	P52333	JAK3	Y904	R911C	911	Missense	distal	7	no	108.604	106.985	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	65.077	Down-regulation
TK_Jak_JAK3_Y	P52333	JAK3	P52333	JAK3	Y904	G908S	908	Missense	distal	4	no	108.604	109.960	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	65.077	Up-regulation
TK_Jak_JAK3_Y	P52333	JAK3	P52333	JAK3	Y939	V946M	946	Missense	distal	7	no	106.715	106.313	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	65.077	Down-regulation
TK_Jak_JAK3_Y	P52333	JAK3	P52333	JAK3	Y939	M937I	937	Missense	proximal	-2	no	106.715	106.326	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	65.077	Down-regulation
TK_Jak_JAK3_Y	P52333	JAK3	P52333	JAK3	Y980	G987S	987	Missense	distal	7	no	109.461	109.723	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	65.077	Up-regulation
TK_Jak_JAK3_Y	P52333	JAK3	P52333	JAK3	Y980	G987D	987	Missense	distal	7	no	109.461	109.143	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	65.077	Down-regulation
TK_Jak_JAK3_Y	P52333	JAK3	P52333	JAK3	Y981	G987S	987	Missense	distal	6	no	114.399	112.915	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	65.077	Down-regulation
TK_Jak_JAK3_Y	P52333	JAK3	P52333	JAK3	Y981	G987D	987	Missense	distal	6	no	114.399	114.608	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	65.077	Up-regulation
TK_Jak_JAK3_Y	P42229	STAT5A	P52333	JAK3	Y694	Q698P	698	Missense	distal	4	no	107.279	89.169	PhosphoSitePlus	TCGA;ICGC	65.077	Down-regulation
TK_Jak_JAK3_Y	P23458	JAK1	P52333	JAK3	Y993	R997W	997	Missense	distal	4	no	113.858	95.036	EPSD	TCGA;ICGC;COSMIC	65.077	Down-regulation
TK_Jak_JAK3_Y	P23458	JAK1	P52333	JAK3	Y993	Y999H	999	Missense	distal	6	no	113.858	113.776	EPSD	TCGA;ICGC;COSMIC	65.077	Down-regulation
TK_Jak_JAK3_Y	P23458	JAK1	P52333	JAK3	Y993	S996Y	996	Missense	distal	3	no	113.858	106.193	EPSD	TCGA;ICGC;COSMIC	65.077	Down-regulation
TK_Jak_JAK3_Y	P23458	JAK1	P52333	JAK3	Y1034	E1033D	1033	Missense	proximal	-1	no	121.690	128.196	PhosphoSitePlus;EPSD	TCGA;ICGC;COSMIC	65.077	Up-regulation
TK_Jak_JAK3_Y	P23458	JAK1	P52333	JAK3	Y1034	Y1034H	1034	Missense	central	0	yes	121.690	0.000	PhosphoSitePlus;EPSD	TCGA;ICGC;COSMIC	65.077	Loss
TK_Jak_JAK3_Y	P23458	JAK1	P52333	JAK3	Y1035	E1033D	1033	Missense	proximal	-2	no	109.428	109.373	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	65.077	Down-regulation
TK_Jak_JAK3_Y	P23458	JAK1	P52333	JAK3	Y1035	Y1034H	1034	Missense	proximal	-1	no	109.428	106.188	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	65.077	Down-regulation
TK_Jak_JAK3_Y	Q96LC7	SIGLEC10	P52333	JAK3	Y597	N599D	599	Missense	proximal	2	no	72.626	72.897	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	65.077	Up-regulation
TK_Jak_JAK3_Y	Q96LC7	SIGLEC10	P52333	JAK3	Y641	Q637H	637	Missense	distal	-4	no	85.795	85.430	EPSD	TCGA;COSMIC	65.077	Down-regulation
TK_Jak_JAK3_Y	Q96LC7	SIGLEC10	P52333	JAK3	Y667	E663Q	663	Missense	distal	-4	no	93.502	93.261	PhosphoSitePlus;EPSD	TCGA;COSMIC	65.077	Down-regulation
TK_Jak_JAK3_Y	Q96LC7	SIGLEC10	P52333	JAK3	Y667	E660K	660	Missense	distal	-7	no	93.502	95.238	PhosphoSitePlus;EPSD	TCGA;COSMIC	65.077	Up-regulation
TK_Jak_JAK3_Y	Q96LC7	SIGLEC10	P52333	JAK3	Y667	Q662L	662	Missense	distal	-5	no	93.502	96.341	PhosphoSitePlus;EPSD	TCGA;COSMIC	65.077	Up-regulation
TK_Jak_JAK3_Y	Q96LC7	SIGLEC10	P52333	JAK3	Y691	F696L	696	Missense	distal	5	no	77.155	76.787	EPSD;PhosphoSitePlus	TCGA;ICGC	65.077	Down-regulation
TK_Jak_JAK3_Y	P35222	CTNNB1	P52333	JAK3	Y30	G34R	34	Missense	distal	4	no	109.963	108.529	EPSD;PhosphoSitePlus	TCGA;COSMIC	65.077	Down-regulation
TK_Jak_JAK3_Y	P35222	CTNNB1	P52333	JAK3	Y30	G34V	34	Missense	distal	4	no	109.963	102.061	EPSD;PhosphoSitePlus	TCGA;COSMIC;CCLE	65.077	Down-regulation
TK_Jak_JAK3_Y	P35222	CTNNB1	P52333	JAK3	Y30	G34E	34	Missense	distal	4	no	109.963	112.815	EPSD;PhosphoSitePlus	TCGA;COSMIC;GDSC;CCLE	65.077	Up-regulation
TK_Jak_JAK3_Y	P35222	CTNNB1	P52333	JAK3	Y30	S37C	37	Missense	distal	7	no	109.963	107.412	EPSD;PhosphoSitePlus	TCGA;COSMIC;GDSC;CCLE	65.077	Down-regulation
TK_Jak_JAK3_Y	P35222	CTNNB1	P52333	JAK3	Y30	S37F	37	Missense	distal	7	no	109.963	108.884	EPSD;PhosphoSitePlus	TCGA;COSMIC;GDSC;CCLE	65.077	Down-regulation
TK_Jak_JAK3_Y	P35222	CTNNB1	P52333	JAK3	Y30	S33F	33	Missense	distal	3	no	109.963	103.363	EPSD;PhosphoSitePlus	TCGA;COSMIC;GDSC;CCLE	65.077	Down-regulation
TK_Jak_JAK3_Y	P35222	CTNNB1	P52333	JAK3	Y30	D32H	32	Missense	proximal	2	no	109.963	109.574	EPSD;PhosphoSitePlus	TCGA;COSMIC	65.077	Down-regulation
TK_Jak_JAK3_Y	P35222	CTNNB1	P52333	JAK3	Y30	D32G	32	Missense	proximal	2	no	109.963	109.671	EPSD;PhosphoSitePlus	TCGA;COSMIC	65.077	Down-regulation
TK_Jak_JAK3_Y	P35222	CTNNB1	P52333	JAK3	Y30	S33A	33	Missense	distal	3	no	109.963	110.084	EPSD;PhosphoSitePlus	TCGA;COSMIC	65.077	Up-regulation
TK_Jak_JAK3_Y	P35222	CTNNB1	P52333	JAK3	Y30	S33Y	33	Missense	distal	3	no	109.963	102.298	EPSD;PhosphoSitePlus	TCGA;COSMIC;GDSC;CCLE	65.077	Down-regulation
TK_Jak_JAK3_Y	P35222	CTNNB1	P52333	JAK3	Y30	D32V	32	Missense	proximal	2	no	109.963	110.951	EPSD;PhosphoSitePlus	TCGA;COSMIC;CCLE	65.077	Up-regulation
TK_Jak_JAK3_Y	P35222	CTNNB1	P52333	JAK3	Y30	S33P	33	Missense	distal	3	no	109.963	101.882	EPSD;PhosphoSitePlus	TCGA;COSMIC;CCLE	65.077	Down-regulation
TK_Jak_JAK3_Y	P35222	CTNNB1	P52333	JAK3	Y30	H36P	36	Missense	distal	6	no	109.963	109.402	EPSD;PhosphoSitePlus	TCGA;COSMIC;CCLE	65.077	Down-regulation
TK_Jak_JAK3_Y	P35222	CTNNB1	P52333	JAK3	Y30	D32Y	32	Missense	proximal	2	no	109.963	109.205	EPSD;PhosphoSitePlus	TCGA;COSMIC;CCLE	65.077	Down-regulation
TK_Jak_JAK3_Y	P35222	CTNNB1	P52333	JAK3	Y30	I35S	35	Missense	distal	5	no	109.963	106.877	EPSD;PhosphoSitePlus	TCGA;COSMIC	65.077	Down-regulation
TK_Jak_JAK3_Y	P35222	CTNNB1	P52333	JAK3	Y30	S37Y	37	Missense	distal	7	no	109.963	108.478	EPSD;PhosphoSitePlus	TCGA;COSMIC	65.077	Down-regulation
TK_Jak_JAK3_Y	P35222	CTNNB1	P52333	JAK3	Y30	S33C	33	Missense	distal	3	no	109.963	98.243	EPSD;PhosphoSitePlus	TCGA;COSMIC;GDSC;CCLE	65.077	Down-regulation
TK_Jak_JAK3_Y	P35222	CTNNB1	P52333	JAK3	Y30	S37A	37	Missense	distal	7	no	109.963	109.938	EPSD;PhosphoSitePlus	TCGA;COSMIC;GDSC;CCLE	65.077	Down-regulation
TK_Jak_JAK3_Y	P35222	CTNNB1	P52333	JAK3	Y30	D32N	32	Missense	proximal	2	no	109.963	109.692	EPSD;PhosphoSitePlus	TCGA;COSMIC;CCLE	65.077	Down-regulation
TK_Jak_JAK3_Y	P35222	CTNNB1	P52333	JAK3	Y30	S33T	33	Missense	distal	3	no	109.963	106.187	EPSD;PhosphoSitePlus	TCGA;COSMIC	65.077	Down-regulation
TK_Jak_JAK3_Y	P35222	CTNNB1	P52333	JAK3	Y30	S37P	37	Missense	distal	7	no	109.963	108.957	EPSD;PhosphoSitePlus	TCGA;COSMIC;GDSC;CCLE	65.077	Down-regulation
TK_Jak_JAK3_Y	P35222	CTNNB1	P52333	JAK3	Y30	D32A	32	Missense	proximal	2	no	109.963	110.885	EPSD;PhosphoSitePlus	TCGA;COSMIC	65.077	Up-regulation
TK_Jak_JAK3_Y	P35222	CTNNB1	P52333	JAK3	Y64	S60F	60	Missense	distal	-4	no	100.828	99.711	EPSD;PhosphoSitePlus	TCGA;COSMIC	65.077	Down-regulation
TK_Jak_JAK3_Y	P35222	CTNNB1	P52333	JAK3	Y86	R90Q	90	Missense	distal	4	no	110.336	114.689	PhosphoSitePlus;EPSD	TCGA;COSMIC	65.077	Up-regulation
TK_Jak_JAK3_Y	P35222	CTNNB1	P52333	JAK3	Y86	R90L	90	Missense	distal	4	no	110.336	90.302	PhosphoSitePlus;EPSD	TCGA	65.077	Down-regulation
TK_Jak_JAK3_Y	P35222	CTNNB1	P52333	JAK3	Y86	G84R	84	Missense	proximal	-2	no	110.336	109.335	PhosphoSitePlus;EPSD	TCGA;COSMIC	65.077	Down-regulation
TK_Jak_JAK3_Y	P35222	CTNNB1	P52333	JAK3	Y86	A80T	80	Missense	distal	-6	no	110.336	110.290	PhosphoSitePlus;EPSD	TCGA	65.077	Down-regulation
TK_Jak_JAK3_Y	P35222	CTNNB1	P52333	JAK3	Y331	E334A	334	Missense	distal	3	no	69.894	73.091	EPSD	TCGA;COSMIC	65.077	Up-regulation
TK_Jak_JAK3_Y	P35222	CTNNB1	P52333	JAK3	Y331	K335T	335	Missense	distal	4	no	69.894	58.848	EPSD	TCGA;COSMIC	65.077	Loss
TK_Jak_JAK3_Y	P35222	CTNNB1	P52333	JAK3	Y331	K335I	335	Missense	distal	4	no	69.894	48.353	EPSD	TCGA;COSMIC	65.077	Loss
TK_Jak_JAK3_Y	P35222	CTNNB1	P52333	JAK3	Y331	Y333F	333	Missense	proximal	2	no	69.894	70.260	EPSD	TCGA;COSMIC	65.077	Up-regulation
TK_Jak_JAK3_Y	P35222	CTNNB1	P52333	JAK3	Y331	M328I	328	Missense	distal	-3	no	69.894	68.199	EPSD	TCGA;COSMIC	65.077	Down-regulation
TK_Jak_JAK3_Y	P35222	CTNNB1	P52333	JAK3	Y331	E334K	334	Missense	distal	3	no	69.894	69.159	EPSD	TCGA;COSMIC;GDSC;CCLE	65.077	Down-regulation
TK_Jak_JAK3_Y	P35222	CTNNB1	P52333	JAK3	Y331	L336P	336	Missense	distal	5	no	69.894	68.891	EPSD	TCGA;COSMIC	65.077	Down-regulation
TK_Jak_JAK3_Y	Q15717	ELAVL1	P52333	JAK3	Y63	S60N	60	Missense	distal	-3	no	110.612	108.349	PhosphoSitePlus;EPSD	TCGA;ICGC;COSMIC	65.077	Down-regulation
TK_Jak_JAK3_Y	Q15717	ELAVL1	P52333	JAK3	Y63	S60I	60	Missense	distal	-3	no	110.612	107.314	PhosphoSitePlus;EPSD	TCGA;ICGC	65.077	Down-regulation
TK_Jak_JAK3_Y	Q15717	ELAVL1	P52333	JAK3	Y68	A71V	71	Missense	distal	3	no	99.871	99.336	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC;GDSC;CCLE	65.077	Down-regulation
TK_Jak_JAK3_Y	Q15717	ELAVL1	P52333	JAK3	Y68	E75D	75	Missense	distal	7	no	99.871	99.556	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	65.077	Down-regulation
TK_Jak_JAK3_Y	Q15717	ELAVL1	P52333	JAK3	Y200	H201Q	201	Missense	proximal	1	no	104.116	103.747	EPSD;PhosphoSitePlus	TCGA;ICGC	65.077	Down-regulation
TK_Jak_JAK3_Y	P42224	STAT1	P52333	JAK3	Y701	E705K	705	Missense	distal	4	no	110.959	113.887	PhosphoSitePlus	TCGA;ICGC;COSMIC	65.077	Up-regulation
TK_Tec_ITK_Y	Q06187	BTK	Q08881	ITK	Y223	K218N	218	Missense	distal	-5	no	18.601	17.768	PhosphoSitePlus	TCGA;ICGC;COSMIC	9.294	Down-regulation
TK_Tec_ITK_Y	Q06187	BTK	Q08881	ITK	Y225	K218N	218	Missense	distal	-7	no	12.025	11.797	EPSD	TCGA;ICGC;COSMIC	9.294	Down-regulation
TK_Tec_ITK_Y	Q08881	ITK	Q08881	ITK	Y180	D181H	181	Missense	proximal	1	no	18.295	18.458	PhosphoSitePlus	TCGA;ICGC;COSMIC	9.294	Up-regulation
TK_Tec_ITK_Y	Q08881	ITK	Q08881	ITK	Y180	P187T	187	Missense	distal	7	no	18.295	18.355	PhosphoSitePlus	TCGA;ICGC;COSMIC;GDSC;CCLE	9.294	Up-regulation
TK_Tec_ITK_Y	Q08881	ITK	Q08881	ITK	Y180	E173K	173	Missense	distal	-7	no	18.295	17.634	PhosphoSitePlus	TCGA;ICGC;COSMIC	9.294	Down-regulation
TK_Tec_ITK_Y	Q08881	ITK	Q08881	ITK	Y180	V175M	175	Missense	distal	-5	no	18.295	18.348	PhosphoSitePlus	TCGA;ICGC	9.294	Up-regulation
TK_Tec_ITK_Y	Q08881	ITK	Q08881	ITK	Y182	D181H	181	Missense	proximal	-1	no	9.788	9.804	EPSD	TCGA;ICGC;COSMIC	9.294	Up-regulation
TK_Tec_ITK_Y	Q08881	ITK	Q08881	ITK	Y182	P187T	187	Missense	distal	5	no	9.788	8.146	EPSD	TCGA;ICGC;COSMIC;GDSC;CCLE	9.294	Loss
TK_Tec_ITK_Y	Q08881	ITK	Q08881	ITK	Y182	V175M	175	Missense	distal	-7	no	9.788	9.903	EPSD	TCGA;ICGC	9.294	Up-regulation
TK_Tec_ITK_Y	Q9H4E7	DEF6	Q08881	ITK	Y210	L213R	213	Missense	distal	3	no	16.327	16.322	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	9.294	Down-regulation
TK_Tec_ITK_Y	Q9H4E7	DEF6	Q08881	ITK	Y210	E212V	212	Missense	proximal	2	no	16.327	15.873	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	9.294	Down-regulation
TK_Tec_ITK_Y	Q9H4E7	DEF6	Q08881	ITK	Y222	R226Q	226	Missense	distal	4	no	19.489	19.415	PhosphoSitePlus;EPSD	TCGA;ICGC;COSMIC	9.294	Down-regulation
TK_Tec_ITK_Y	Q9H4E7	DEF6	Q08881	ITK	Y222	W224L	224	Missense	proximal	2	no	19.489	19.288	PhosphoSitePlus;EPSD	TCGA;ICGC;COSMIC	9.294	Down-regulation
TK_Tec_ITK_Y	P19174	PLCG1	Q08881	ITK	Y93	R92G	92	Missense	proximal	-1	no	12.748	13.011	EPSD	TCGA;ICGC;COSMIC	9.294	Up-regulation
TK_Tec_ITK_Y	P19174	PLCG1	Q08881	ITK	Y93	R88Q	88	Missense	distal	-5	no	12.748	12.854	EPSD	TCGA;ICGC;COSMIC	9.294	Up-regulation
TK_Tec_ITK_Y	P19174	PLCG1	Q08881	ITK	Y775	F782L	782	Missense	distal	7	no	10.668	10.619	EPSD	TCGA;ICGC;COSMIC	9.294	Down-regulation
TK_Tec_ITK_Y	P19174	PLCG1	Q08881	ITK	Y775	R778C	778	Missense	distal	3	no	10.668	10.362	EPSD	TCGA;ICGC;COSMIC;GDSC;CCLE	9.294	Down-regulation
TK_Tec_ITK_Y	P19174	PLCG1	Q08881	ITK	Y783	F782L	782	Missense	proximal	-1	no	19.117	18.787	PhosphoSitePlus	TCGA;ICGC;COSMIC	9.294	Down-regulation
TK_Tec_ITK_Y	P19174	PLCG1	Q08881	ITK	Y783	P788H	788	Missense	distal	5	no	19.117	16.948	PhosphoSitePlus	TCGA;ICGC	9.294	Down-regulation
TK_Tec_ITK_Y	P19174	PLCG1	Q08881	ITK	Y783	R778C	778	Missense	distal	-5	no	19.117	17.297	PhosphoSitePlus	TCGA;ICGC;COSMIC;GDSC;CCLE	9.294	Down-regulation
TK_Tec_ITK_Y	P51813	BMX	Q08881	ITK	Y216	Y216H	216	Missense	central	0	yes	20.962	0.000	PhosphoSitePlus	TCGA;ICGC;COSMIC	9.294	Loss
TK_Tec_ITK_Y	Q96LC7	SIGLEC10	Q08881	ITK	Y597	N599D	599	Missense	proximal	2	no	20.710	20.726	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	9.294	Up-regulation
TK_Tec_ITK_Y	Q96LC7	SIGLEC10	Q08881	ITK	Y641	Q637H	637	Missense	distal	-4	no	9.591	9.297	EPSD	TCGA;COSMIC	9.294	Down-regulation
TK_Tec_ITK_Y	Q96LC7	SIGLEC10	Q08881	ITK	Y667	E663Q	663	Missense	distal	-4	no	18.530	18.553	PhosphoSitePlus;EPSD	TCGA;COSMIC	9.294	Up-regulation
TK_Tec_ITK_Y	Q96LC7	SIGLEC10	Q08881	ITK	Y667	E660K	660	Missense	distal	-7	no	18.530	17.869	PhosphoSitePlus;EPSD	TCGA;COSMIC	9.294	Down-regulation
TK_Tec_ITK_Y	Q96LC7	SIGLEC10	Q08881	ITK	Y667	Q662L	662	Missense	distal	-5	no	18.530	17.619	PhosphoSitePlus;EPSD	TCGA;COSMIC	9.294	Down-regulation
TK_Tec_ITK_Y	Q96LC7	SIGLEC10	Q08881	ITK	Y691	F696L	696	Missense	distal	5	no	12.973	12.941	EPSD	TCGA;ICGC	9.294	Down-regulation
TK_Tec_ITK_Y	Q8TDQ0	HAVCR2	Q08881	ITK	Y265	I264F	264	Missense	proximal	-1	no	20.501	20.657	PhosphoSitePlus	TCGA;ICGC;COSMIC	9.294	Up-regulation
TK_Tec_ITK_Y	Q8TDQ0	HAVCR2	Q08881	ITK	Y265	R259L	259	Missense	distal	-6	no	20.501	20.024	PhosphoSitePlus	TCGA;ICGC;COSMIC	9.294	Down-regulation
TK_Tec_ITK_Y	Q8TDQ0	HAVCR2	Q08881	ITK	Y265	R259C	259	Missense	distal	-6	no	20.501	20.062	PhosphoSitePlus	TCGA;ICGC;COSMIC	9.294	Down-regulation
TK_Tec_ITK_Y	Q13094	LCP2	Q08881	ITK	Y145	A143E	143	Missense	proximal	-2	no	12.142	10.965	EPSD	TCGA;ICGC	9.294	Down-regulation
TK_Tec_ITK_Y	Q13094	LCP2	Q08881	ITK	Y145	V139M	139	Missense	distal	-6	no	12.142	12.222	EPSD	TCGA;ICGC;COSMIC;CCLE	9.294	Up-regulation
TK_Tec_ITK_Y	Q13094	LCP2	Q08881	ITK	Y145	D144E	144	Missense	proximal	-1	no	12.142	12.265	EPSD	TCGA;ICGC;COSMIC	9.294	Up-regulation
TK_Tec_ITK_Y	Q13094	LCP2	Q08881	ITK	Y173	D175Y	175	Missense	proximal	2	no	18.517	18.544	PhosphoSitePlus	TCGA;ICGC;COSMIC	9.294	Up-regulation
TK_Tec_ITK_Y	Q13094	LCP2	Q08881	ITK	Y173	Y173C	173	Missense	central	0	yes	18.517	0.000	PhosphoSitePlus	TCGA;ICGC	9.294	Loss
TK_Tec_ITK_Y	Q13094	LCP2	Q08881	ITK	Y380	S386N	386	Missense	distal	6	no	12.813	12.643	EPSD	TCGA;ICGC;COSMIC	9.294	Down-regulation
TK_Tec_ITK_Y	Q13094	LCP2	Q08881	ITK	Y380	S382C	382	Missense	proximal	2	no	12.813	12.534	EPSD	TCGA;ICGC;COSMIC	9.294	Down-regulation
TK_Tec_ITK_Y	Q13094	LCP2	Q08881	ITK	Y423	W422C	422	Missense	proximal	-1	no	16.033	16.047	EPSD	TCGA;ICGC;COSMIC	9.294	Up-regulation
TK_Tec_ITK_Y	Q13094	LCP2	Q08881	ITK	Y459	P458L	458	Missense	proximal	-1	no	11.079	10.857	EPSD	TCGA;COSMIC	9.294	Down-regulation
TK_Tec_ITK_Y	Q13094	LCP2	Q08881	ITK	Y459	K466N	466	Missense	distal	7	no	11.079	11.061	EPSD	TCGA	9.294	Down-regulation
TK_Tec_ITK_Y	P42680	TEC	Q08881	ITK	Y206	E201K	201	Missense	distal	-5	no	18.351	17.897	PhosphoSitePlus	TCGA;ICGC;COSMIC	9.294	Down-regulation
TK_Tec_ITK_Y	P42680	TEC	Q08881	ITK	Y206	K211N	211	Missense	distal	5	no	18.351	19.279	PhosphoSitePlus	TCGA;ICGC;COSMIC	9.294	Up-regulation
TK_Csk_CSK_Y	P06239	LCK	P41240	CSK	Y72	D77V	77	Missense	distal	5	no	43.094	43.608	EPSD	TCGA;COSMIC	33.668	Up-regulation
TK_Csk_CSK_Y	P06239	LCK	P41240	CSK	Y72	A68V	68	Missense	distal	-4	no	43.094	38.350	EPSD	TCGA	33.668	Down-regulation
TK_Csk_CSK_Y	P06239	LCK	P41240	CSK	Y394	E393G	393	Missense	proximal	-1	no	46.590	37.554	EPSD	TCGA;COSMIC	33.668	Down-regulation
TK_Csk_CSK_Y	P06239	LCK	P41240	CSK	Y394	E393K	393	Missense	proximal	-1	no	46.590	36.276	EPSD	TCGA;COSMIC	33.668	Down-regulation
TK_Csk_CSK_Y	P06239	LCK	P41240	CSK	Y394	A396T	396	Missense	proximal	2	no	46.590	41.154	EPSD	TCGA;COSMIC;CCLE	33.668	Down-regulation
TK_Csk_CSK_Y	P06239	LCK	P41240	CSK	Y505	Y505C	505	Missense	central	0	yes	101.250	0.000	PhosphoSitePlus	TCGA;ICGC	33.668	Loss
TK_Csk_CSK_Y	P12931	SRC	P41240	CSK	Y419	A425V	425	Missense	distal	6	no	34.876	35.409	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC;CCLE	33.668	Up-regulation
TK_Csk_CSK_Y	P12931	SRC	P41240	CSK	Y530	G533E	533	Missense	distal	3	no	115.622	115.853	PhosphoSitePlus;EPSD	TCGA;ICGC	33.668	Up-regulation
TK_Csk_CSK_Y	P12931	SRC	P41240	CSK	Y530	T524M	524	Missense	distal	-6	no	115.622	112.303	PhosphoSitePlus;EPSD	TCGA;ICGC;COSMIC	33.668	Down-regulation
TK_Csk_CSK_Y	P07947	YES1	P41240	CSK	Y537	N542H	542	Missense	distal	5	no	109.039	108.701	PhosphoSitePlus	TCGA	33.668	Down-regulation
TK_Csk_CSK_Y	P08631	HCK	P41240	CSK	Y411	R404Q	404	Missense	distal	-7	no	46.680	47.626	PhosphoSitePlus	TCGA;COSMIC	33.668	Up-regulation
TK_Csk_CSK_Y	P08631	HCK	P41240	CSK	Y411	E407K	407	Missense	distal	-4	no	46.680	41.252	PhosphoSitePlus	TCGA;COSMIC	33.668	Down-regulation
TK_Csk_CSK_Y	P08631	HCK	P41240	CSK	Y411	R414W	414	Missense	distal	3	no	46.680	46.978	PhosphoSitePlus	TCGA;COSMIC	33.668	Up-regulation
TK_Csk_CSK_Y	P08631	HCK	P41240	CSK	Y411	A413T	413	Missense	proximal	2	no	46.680	41.245	PhosphoSitePlus	TCGA;COSMIC	33.668	Down-regulation
TK_Csk_CSK_Y	P08631	HCK	P41240	CSK	Y411	R404W	404	Missense	distal	-7	no	46.680	46.851	PhosphoSitePlus	TCGA;COSMIC	33.668	Up-regulation
TK_Csk_CSK_Y	P08631	HCK	P41240	CSK	Y411	Y411C	411	Missense	central	0	yes	46.680	0.000	PhosphoSitePlus	TCGA	33.668	Loss
TK_Csk_CSK_Y	P08631	HCK	P41240	CSK	Y411	T412M	412	Missense	proximal	1	no	46.680	41.035	PhosphoSitePlus	TCGA;COSMIC	33.668	Down-regulation
TK_Csk_CSK_Y	P08631	HCK	P41240	CSK	Y522	Q523K	523	Missense	proximal	1	no	100.465	86.728	EPSD	TCGA;COSMIC	33.668	Down-regulation
TK_Csk_CSK_Y	P08631	HCK	P41240	CSK	Y522	Y515C	515	Missense	distal	-7	no	100.465	100.389	EPSD	TCGA;COSMIC	33.668	Down-regulation
TK_Csk_CSK_Y	P06241	FYN	P41240	CSK	Y39	G43S	43	Missense	distal	4	no	56.255	59.993	EPSD	TCGA;ICGC;COSMIC	33.668	Up-regulation
TK_Csk_CSK_Y	P06241	FYN	P41240	CSK	Y39	P40S	40	Missense	proximal	1	no	56.255	62.846	EPSD	TCGA;ICGC;COSMIC	33.668	Up-regulation
TK_Csk_CSK_Y	P06241	FYN	P41240	CSK	Y531	E535D	535	Missense	distal	4	no	111.873	111.384	PhosphoSitePlus	TCGA;COSMIC	33.668	Down-regulation
CMGC_MAPK_ERK5_MAPK7_ST	Q13164	MAPK7	Q13164	MAPK7	S14	V21L	21	Missense	distal	7	no	91.021	91.572	EPSD	TCGA;ICGC;COSMIC	81.800	Up-regulation
CMGC_MAPK_ERK5_MAPK7_ST	Q13164	MAPK7	Q13164	MAPK7	T28	V21L	21	Missense	distal	-7	no	108.435	109.490	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	81.800	Up-regulation
CMGC_MAPK_ERK5_MAPK7_ST	Q13164	MAPK7	Q13164	MAPK7	S210	P211S	211	Missense	proximal	1	no	91.311	63.213	EPSD	TCGA;ICGC;COSMIC	81.800	Loss
CMGC_MAPK_ERK5_MAPK7_ST	Q13164	MAPK7	Q13164	MAPK7	S282	A288D	288	Missense	distal	6	no	91.233	93.893	EPSD	TCGA;ICGC;COSMIC	81.800	Up-regulation
CMGC_MAPK_ERK5_MAPK7_ST	Q13164	MAPK7	Q13164	MAPK7	S421	A424S	424	Missense	distal	3	no	107.916	108.679	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	81.800	Up-regulation
CMGC_MAPK_ERK5_MAPK7_ST	Q13164	MAPK7	Q13164	MAPK7	S421	P420S	420	Missense	proximal	-1	no	107.916	108.097	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	81.800	Up-regulation
CMGC_MAPK_ERK5_MAPK7_ST	Q13164	MAPK7	Q13164	MAPK7	S433	A430V	430	Missense	distal	-3	no	106.853	101.403	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	81.800	Down-regulation
CMGC_MAPK_ERK5_MAPK7_ST	Q13164	MAPK7	Q13164	MAPK7	S472	K466N	466	Missense	distal	-6	no	93.483	101.118	EPSD	TCGA;ICGC;COSMIC	81.800	Up-regulation
CMGC_MAPK_ERK5_MAPK7_ST	Q13164	MAPK7	Q13164	MAPK7	S731	G738E	738	Missense	distal	7	no	100.755	101.136	PhosphoSitePlus;EPSD	TCGA;ICGC;COSMIC	81.800	Up-regulation
CMGC_MAPK_ERK5_MAPK7_ST	Q13164	MAPK7	Q13164	MAPK7	T733	G738E	738	Missense	distal	5	no	111.960	112.903	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	81.800	Up-regulation
CMGC_MAPK_ERK5_MAPK7_ST	Q13164	MAPK7	Q13164	MAPK7	S770	D769N	769	Missense	proximal	-1	no	112.602	112.326	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	81.800	Down-regulation
CMGC_MAPK_ERK5_MAPK7_ST	Q13164	MAPK7	Q13164	MAPK7	S772	D769N	769	Missense	distal	-3	no	107.012	108.024	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	81.800	Up-regulation
CMGC_MAPK_ERK5_MAPK7_ST	Q13164	MAPK7	Q13164	MAPK7	S774	D769N	769	Missense	distal	-5	no	119.380	114.392	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	81.800	Down-regulation
CMGC_MAPK_ERK5_MAPK7_ST	Q13164	MAPK7	Q13164	MAPK7	S776	D769N	769	Missense	distal	-7	no	106.005	104.548	EPSD	TCGA;ICGC;COSMIC	81.800	Down-regulation
CMGC_MAPK_ERK5_MAPK7_ST	Q13164	MAPK7	Q13164	MAPK7	S776	E783K	783	Missense	distal	7	no	106.005	106.926	EPSD	TCGA;ICGC;COSMIC	81.800	Up-regulation
CMGC_MAPK_ERK5_MAPK7_ST	P01100	FOS	Q13164	MAPK7	S102	P95S	95	Missense	distal	-7	no	91.462	91.617	EPSD	TCGA;ICGC;COSMIC	81.800	Up-regulation
CMGC_MAPK_ERK5_MAPK7_ST	P01100	FOS	Q13164	MAPK7	S102	A100T	100	Missense	proximal	-2	no	91.462	89.871	EPSD	TCGA;ICGC	81.800	Down-regulation
CMGC_MAPK_ERK5_MAPK7_ST	P01100	FOS	Q13164	MAPK7	S260	M262I	262	Missense	proximal	2	no	79.672	86.641	EPSD	TCGA;COSMIC	81.800	Gain
CMGC_MAPK_ERK5_MAPK7_ST	Q02078	MEF2A	Q13164	MAPK7	S98	D100Y	100	Missense	proximal	2	no	86.031	82.416	EPSD	TCGA;ICGC;COSMIC	81.800	Down-regulation
CMGC_MAPK_ERK5_MAPK7_ST	Q02078	MEF2A	Q13164	MAPK7	S192	P196S	196	Missense	distal	4	no	94.229	97.884	EPSD	TCGA;COSMIC	81.800	Up-regulation
CMGC_MAPK_ERK5_MAPK7_ST	Q02078	MEF2A	Q13164	MAPK7	S192	S192F	192	Missense	central	0	yes	94.229	0.000	EPSD	TCGA;COSMIC	81.800	Loss
CMGC_MAPK_ERK5_MAPK7_ST	Q02078	MEF2A	Q13164	MAPK7	T212	D213N	213	Missense	proximal	1	no	76.850	83.336	EPSD	TCGA	81.800	Gain
CMGC_MAPK_ERK5_MAPK7_ST	Q02078	MEF2A	Q13164	MAPK7	S289	K282R	282	Missense	distal	-7	no	88.758	88.381	EPSD	TCGA;ICGC;COSMIC	81.800	Down-regulation
CMGC_MAPK_ERK5_MAPK7_ST	Q12959	DLG1	Q13164	MAPK7	S70	R69C	69	Missense	proximal	-1	no	85.119	85.596	EPSD	TCGA;ICGC;COSMIC	81.800	Up-regulation
CMGC_MAPK_ERK5_MAPK7_ST	Q12959	DLG1	Q13164	MAPK7	S70	N63T	63	Missense	distal	-7	no	85.119	86.387	EPSD	TCGA;ICGC;COSMIC	81.800	Up-regulation
CMGC_MAPK_ERK5_MAPK7_ST	Q12959	DLG1	Q13164	MAPK7	S70	D68Y	68	Missense	proximal	-2	no	85.119	81.144	EPSD	TCGA;ICGC	81.800	Loss
CMGC_MAPK_ERK5_MAPK7_ST	Q12959	DLG1	Q13164	MAPK7	S86	E83K	83	Missense	distal	-3	no	89.177	87.463	EPSD	TCGA;ICGC;COSMIC	81.800	Down-regulation
CMGC_MAPK_ERK5_MAPK7_ST	Q12959	DLG1	Q13164	MAPK7	S86	I84M	84	Missense	proximal	-2	no	89.177	90.203	EPSD	TCGA;ICGC;COSMIC	81.800	Up-regulation
CMGC_MAPK_ERK5_MAPK7_ST	Q12959	DLG1	Q13164	MAPK7	S94	E95Q	95	Missense	proximal	1	no	68.721	85.708	EPSD	TCGA;ICGC;COSMIC	81.800	Gain
CMGC_MAPK_ERK5_MAPK7_ST	Q12959	DLG1	Q13164	MAPK7	S100	E95Q	95	Missense	distal	-5	no	93.013	91.179	EPSD	TCGA;ICGC;COSMIC	81.800	Down-regulation
CMGC_MAPK_ERK5_MAPK7_ST	Q12959	DLG1	Q13164	MAPK7	S100	S100C	100	Missense	central	0	yes	93.013	0.000	EPSD	TCGA;ICGC;COSMIC	81.800	Loss
CMGC_MAPK_ERK5_MAPK7_ST	Q12959	DLG1	Q13164	MAPK7	S102	E95Q	95	Missense	distal	-7	no	90.047	88.561	EPSD	TCGA;ICGC;COSMIC	81.800	Down-regulation
CMGC_MAPK_ERK5_MAPK7_ST	Q12959	DLG1	Q13164	MAPK7	S102	S100C	100	Missense	proximal	-2	no	90.047	81.833	EPSD	TCGA;ICGC;COSMIC	81.800	Down-regulation
CMGC_MAPK_ERK5_MAPK7_ST	Q12959	DLG1	Q13164	MAPK7	S122	P116L	116	Missense	distal	-6	no	94.597	92.057	EPSD	TCGA;ICGC;COSMIC	81.800	Down-regulation
CMGC_MAPK_ERK5_MAPK7_ST	Q12959	DLG1	Q13164	MAPK7	S122	P116S	116	Missense	distal	-6	no	94.597	94.070	EPSD	TCGA;ICGC;COSMIC	81.800	Down-regulation
CMGC_MAPK_ERK5_MAPK7_ST	Q12959	DLG1	Q13164	MAPK7	S158	A165S	165	Missense	distal	7	no	107.598	107.460	PhosphoSitePlus	TCGA;ICGC;COSMIC	81.800	Down-regulation
CMGC_MAPK_ERK5_MAPK7_ST	Q12959	DLG1	Q13164	MAPK7	S435	A442V	442	Missense	distal	7	no	84.313	82.727	EPSD	TCGA;COSMIC	81.800	Down-regulation
CMGC_MAPK_ERK5_MAPK7_ST	Q12959	DLG1	Q13164	MAPK7	S435	D428H	428	Missense	distal	-7	no	84.313	83.522	EPSD	TCGA;COSMIC	81.800	Down-regulation
CMGC_MAPK_ERK5_MAPK7_ST	Q12959	DLG1	Q13164	MAPK7	S435	S432G	432	Missense	distal	-3	no	84.313	85.395	EPSD	TCGA;COSMIC	81.800	Up-regulation
CMGC_MAPK_ERK5_MAPK7_ST	Q12959	DLG1	Q13164	MAPK7	S443	A442V	442	Missense	proximal	-1	no	84.273	85.351	EPSD	TCGA;COSMIC	81.800	Up-regulation
CMGC_MAPK_ERK5_MAPK7_ST	Q12959	DLG1	Q13164	MAPK7	S448	A442V	442	Missense	distal	-6	no	97.159	87.627	EPSD	TCGA;COSMIC	81.800	Down-regulation
CMGC_MAPK_ERK5_MAPK7_ST	Q12959	DLG1	Q13164	MAPK7	S575	S568I	568	Missense	distal	-7	no	89.841	89.483	EPSD	TCGA;COSMIC	81.800	Down-regulation
CMGC_MAPK_ERK5_MAPK7_ST	Q12959	DLG1	Q13164	MAPK7	S575	G574C	574	Missense	proximal	-1	no	89.841	90.540	EPSD	TCGA;COSMIC	81.800	Up-regulation
CMGC_MAPK_ERK5_MAPK7_ST	Q12959	DLG1	Q13164	MAPK7	S579	G574C	574	Missense	distal	-5	no	88.990	83.298	EPSD	TCGA;COSMIC	81.800	Down-regulation
CMGC_MAPK_ERK5_MAPK7_ST	Q12959	DLG1	Q13164	MAPK7	S598	P601S	601	Missense	distal	3	no	88.380	87.940	EPSD	TCGA;COSMIC	81.800	Down-regulation
CMGC_MAPK_ERK5_MAPK7_ST	Q13163	MAP2K5	Q13164	MAPK7	S129	A126S	126	Missense	distal	-3	no	105.888	105.248	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	81.800	Down-regulation
CMGC_MAPK_ERK5_MAPK7_ST	Q13163	MAP2K5	Q13164	MAPK7	S129	G127V	127	Missense	proximal	-2	no	105.888	103.185	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	81.800	Down-regulation
CMGC_MAPK_ERK5_MAPK7_ST	Q13163	MAP2K5	Q13164	MAPK7	S129	G127R	127	Missense	proximal	-2	no	105.888	101.986	EPSD;PhosphoSitePlus	TCGA;ICGC	81.800	Down-regulation
CMGC_MAPK_ERK5_MAPK7_ST	Q13163	MAP2K5	Q13164	MAPK7	S129	V136I	136	Missense	distal	7	no	105.888	106.794	EPSD;PhosphoSitePlus	TCGA;ICGC	81.800	Up-regulation
CMGC_MAPK_ERK5_MAPK7_ST	Q13163	MAP2K5	Q13164	MAPK7	S137	V136I	136	Missense	proximal	-1	no	110.596	110.491	EPSD;PhosphoSitePlus	TCGA;ICGC	81.800	Down-regulation
CMGC_MAPK_ERK5_MAPK7_ST	Q13163	MAP2K5	Q13164	MAPK7	S142	V136I	136	Missense	distal	-6	no	107.084	110.380	PhosphoSitePlus;EPSD	TCGA;ICGC	81.800	Up-regulation
CMGC_MAPK_ERK5_MAPK7_ST	Q06413	MEF2C	Q13164	MAPK7	T80	H76L	76	Missense	distal	-4	no	89.534	90.422	EPSD	TCGA	81.800	Up-regulation
CMGC_MAPK_ERK5_MAPK7_ST	Q06413	MEF2C	Q13164	MAPK7	T80	E74V	74	Missense	distal	-6	no	89.534	81.891	EPSD	TCGA;ICGC;COSMIC	81.800	Down-regulation
CMGC_MAPK_ERK5_MAPK7_ST	Q06413	MEF2C	Q13164	MAPK7	T80	V85M	85	Missense	distal	5	no	89.534	90.011	EPSD	TCGA;ICGC;COSMIC	81.800	Up-regulation
CMGC_MAPK_ERK5_MAPK7_ST	Q06413	MEF2C	Q13164	MAPK7	S98	A103V	103	Missense	distal	5	no	96.927	94.591	EPSD	TCGA;ICGC	81.800	Down-regulation
CMGC_MAPK_ERK5_MAPK7_ST	Q06413	MEF2C	Q13164	MAPK7	S98	C96F	96	Missense	proximal	-2	no	96.927	100.174	EPSD	TCGA;ICGC;COSMIC	81.800	Up-regulation
CMGC_MAPK_ERK5_MAPK7_ST	Q06413	MEF2C	Q13164	MAPK7	S110	A103V	103	Missense	distal	-7	no	95.125	94.275	EPSD	TCGA;ICGC	81.800	Down-regulation
CMGC_MAPK_ERK5_MAPK7_ST	Q06413	MEF2C	Q13164	MAPK7	S110	S106F	106	Missense	distal	-4	no	95.125	93.147	EPSD	TCGA;ICGC;COSMIC	81.800	Down-regulation
CMGC_MAPK_ERK5_MAPK7_ST	Q06413	MEF2C	Q13164	MAPK7	S387	S387I	387	Missense	central	0	yes	104.408	0.000	PhosphoSitePlus	TCGA;COSMIC	81.800	Loss
CMGC_MAPK_ERK5_MAPK7_ST	Q06413	MEF2C	Q13164	MAPK7	S428	S429P	429	Missense	proximal	1	no	56.319	84.418	EPSD	TCGA;COSMIC	81.800	Gain
CMGC_MAPK_ERK5_MAPK7_ST	P29590	PML	Q13164	MAPK7	S399	E405K	405	Missense	distal	6	no	84.948	83.352	EPSD	TCGA;ICGC	81.800	Down-regulation
CMGC_MAPK_ERK5_MAPK7_ST	P29590	PML	Q13164	MAPK7	S403	P410S	410	Missense	distal	7	no	108.190	108.494	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	81.800	Up-regulation
CMGC_MAPK_ERK5_MAPK7_ST	P29590	PML	Q13164	MAPK7	S403	E405K	405	Missense	proximal	2	no	108.190	111.690	EPSD;PhosphoSitePlus	TCGA;ICGC	81.800	Up-regulation
CMGC_MAPK_ERK5_MAPK7_ST	P29590	PML	Q13164	MAPK7	T409	P410S	410	Missense	proximal	1	no	107.565	79.467	PhosphoSitePlus;EPSD	TCGA;ICGC;COSMIC	81.800	Loss
CMGC_MAPK_ERK5_MAPK7_ST	P29590	PML	Q13164	MAPK7	T409	E405K	405	Missense	distal	-4	no	107.565	108.420	PhosphoSitePlus;EPSD	TCGA;ICGC	81.800	Up-regulation
CMGC_MAPK_ERK5_MAPK7_ST	P29590	PML	Q13164	MAPK7	T409	P413L	413	Missense	distal	4	no	107.565	106.515	PhosphoSitePlus;EPSD	TCGA;ICGC;COSMIC	81.800	Down-regulation
CMGC_MAPK_ERK5_MAPK7_ST	P29590	PML	Q13164	MAPK7	S505	L501F	501	Missense	distal	-4	no	92.499	89.279	EPSD	TCGA;ICGC;COSMIC	81.800	Down-regulation
CMGC_MAPK_ERK5_MAPK7_ST	P29590	PML	Q13164	MAPK7	S514	S518L	518	Missense	distal	4	no	82.293	77.589	EPSD	TCGA;ICGC;COSMIC	81.800	Loss
CMGC_MAPK_ERK5_MAPK7_ST	P29590	PML	Q13164	MAPK7	S518	S518L	518	Missense	central	0	yes	91.672	0.000	EPSD	TCGA;ICGC;COSMIC	81.800	Loss
CMGC_MAPK_ERK5_MAPK7_ST	P29590	PML	Q13164	MAPK7	S542	H544Y	544	Missense	proximal	2	no	83.652	77.922	EPSD	TCGA;ICGC	81.800	Loss
CMGC_MAPK_ERK5_MAPK7_ST	P29590	PML	Q13164	MAPK7	S560	S561N	561	Missense	proximal	1	no	72.049	89.427	EPSD	TCGA;ICGC;COSMIC	81.800	Gain
CMGC_MAPK_ERK5_MAPK7_ST	P29590	PML	Q13164	MAPK7	S578	S582P	582	Missense	distal	4	no	96.073	92.417	EPSD	TCGA	81.800	Down-regulation
CMGC_MAPK_ERK5_MAPK7_ST	P29590	PML	Q13164	MAPK7	S579	S582P	582	Missense	distal	3	no	86.463	86.903	EPSD	TCGA	81.800	Up-regulation
CMGC_MAPK_ERK5_MAPK7_ST	P29590	PML	Q13164	MAPK7	S580	S582P	582	Missense	proximal	2	no	87.629	81.473	EPSD	TCGA	81.800	Loss
CMGC_MAPK_ERK5_MAPK7_ST	P29590	PML	Q13164	MAPK7	T592	L593I	593	Missense	proximal	1	no	85.995	51.937	EPSD	TCGA	81.800	Loss
CMGC_MAPK_ERK5_MAPK7_ST	P14921	ETS1	Q13164	MAPK7	S26	P27S	27	Missense	proximal	1	no	95.703	67.605	EPSD	TCGA;ICGC	81.800	Loss
CMGC_DYRK_HIPK_HIPK2_ST	Q9P1Z0	ZBTB4	Q9H2X6	HIPK2	S88	A83S	83	Missense	distal	-5	no	94.879	99.461	EPSD	TCGA;ICGC;COSMIC	98.777	Gain
CMGC_DYRK_HIPK_HIPK2_ST	Q9P1Z0	ZBTB4	Q9H2X6	HIPK2	S90	S94F	94	Missense	distal	4	no	101.860	95.782	EPSD	TCGA;ICGC;COSMIC	98.777	Loss
CMGC_DYRK_HIPK_HIPK2_ST	Q9P1Z0	ZBTB4	Q9H2X6	HIPK2	S90	A83S	83	Missense	distal	-7	no	101.860	100.989	EPSD	TCGA;ICGC;COSMIC	98.777	Down-regulation
CMGC_DYRK_HIPK_HIPK2_ST	Q9P1Z0	ZBTB4	Q9H2X6	HIPK2	S91	S94F	94	Missense	distal	3	no	100.976	100.228	EPSD	TCGA;ICGC;COSMIC	98.777	Down-regulation
CMGC_DYRK_HIPK_HIPK2_ST	Q9P1Z0	ZBTB4	Q9H2X6	HIPK2	S92	S94F	94	Missense	proximal	2	no	101.620	98.729	EPSD	TCGA;ICGC;COSMIC	98.777	Loss
CMGC_DYRK_HIPK_HIPK2_ST	Q9P1Z0	ZBTB4	Q9H2X6	HIPK2	S93	S94F	94	Missense	proximal	1	no	99.614	59.541	EPSD	TCGA;ICGC;COSMIC	98.777	Loss
CMGC_DYRK_HIPK_HIPK2_ST	Q9P1Z0	ZBTB4	Q9H2X6	HIPK2	S104	S109C	109	Missense	distal	5	no	103.114	103.457	EPSD	TCGA;ICGC;COSMIC	98.777	Up-regulation
CMGC_DYRK_HIPK_HIPK2_ST	Q9P1Z0	ZBTB4	Q9H2X6	HIPK2	S391	R385Q	385	Missense	distal	-6	no	106.485	106.849	EPSD	TCGA;ICGC;COSMIC	98.777	Up-regulation
CMGC_DYRK_HIPK_HIPK2_ST	Q9P1Z0	ZBTB4	Q9H2X6	HIPK2	S391	S397C	397	Missense	distal	6	no	106.485	105.576	EPSD	TCGA;ICGC;COSMIC	98.777	Down-regulation
CMGC_DYRK_HIPK_HIPK2_ST	Q9P1Z0	ZBTB4	Q9H2X6	HIPK2	S391	G393V	393	Missense	proximal	2	no	106.485	106.020	EPSD	TCGA;ICGC;COSMIC	98.777	Down-regulation
CMGC_DYRK_HIPK_HIPK2_ST	Q9P1Z0	ZBTB4	Q9H2X6	HIPK2	S541	A545T	545	Missense	distal	4	no	112.412	111.656	EPSD	TCGA;ICGC	98.777	Down-regulation
CMGC_DYRK_HIPK_HIPK2_ST	Q9P1Z0	ZBTB4	Q9H2X6	HIPK2	S629	R624H	624	Missense	distal	-5	no	114.140	103.305	EPSD	TCGA;ICGC;COSMIC	98.777	Down-regulation
CMGC_DYRK_HIPK_HIPK2_ST	Q9P1Z0	ZBTB4	Q9H2X6	HIPK2	S629	E635A	635	Missense	distal	6	no	114.140	113.861	EPSD	TCGA;ICGC;COSMIC	98.777	Down-regulation
CMGC_DYRK_HIPK_HIPK2_ST	Q9P1Z0	ZBTB4	Q9H2X6	HIPK2	S636	E637Q	637	Missense	proximal	1	no	102.742	66.298	EPSD	TCGA;ICGC;COSMIC	98.777	Loss
CMGC_DYRK_HIPK_HIPK2_ST	Q9P1Z0	ZBTB4	Q9H2X6	HIPK2	S636	E638D	638	Missense	proximal	2	no	102.742	100.973	EPSD	TCGA;ICGC;COSMIC	98.777	Down-regulation
CMGC_DYRK_HIPK_HIPK2_ST	Q9P1Z0	ZBTB4	Q9H2X6	HIPK2	S636	E635A	635	Missense	proximal	-1	no	102.742	101.863	EPSD	TCGA;ICGC;COSMIC	98.777	Down-regulation
CMGC_DYRK_HIPK_HIPK2_ST	Q9P1Z0	ZBTB4	Q9H2X6	HIPK2	S687	A682V	682	Missense	distal	-5	no	96.981	99.527	EPSD	TCGA;ICGC;COSMIC	98.777	Gain
CMGC_DYRK_HIPK_HIPK2_ST	Q9P1Z0	ZBTB4	Q9H2X6	HIPK2	T795	P798R	798	Missense	distal	3	no	114.414	114.336	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	98.777	Down-regulation
CMGC_DYRK_HIPK_HIPK2_ST	Q9P1Z0	ZBTB4	Q9H2X6	HIPK2	T795	A789T	789	Missense	distal	-6	no	114.414	114.281	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	98.777	Down-regulation
CMGC_DYRK_HIPK_HIPK2_ST	Q9P1Z0	ZBTB4	Q9H2X6	HIPK2	T797	P798R	798	Missense	proximal	1	no	115.078	102.542	PhosphoSitePlus;EPSD	TCGA;ICGC;COSMIC	98.777	Down-regulation
CMGC_DYRK_HIPK_HIPK2_ST	Q9P1Z0	ZBTB4	Q9H2X6	HIPK2	T797	K804N	804	Missense	distal	7	no	115.078	114.976	PhosphoSitePlus;EPSD	TCGA;ICGC;COSMIC	98.777	Down-regulation
CMGC_DYRK_HIPK_HIPK2_ST	Q9P1Z0	ZBTB4	Q9H2X6	HIPK2	S803	P798R	798	Missense	distal	-5	no	100.740	98.957	EPSD	TCGA;ICGC;COSMIC	98.777	Down-regulation
CMGC_DYRK_HIPK_HIPK2_ST	Q9P1Z0	ZBTB4	Q9H2X6	HIPK2	S803	K804N	804	Missense	proximal	1	no	100.740	73.400	EPSD	TCGA;ICGC;COSMIC	98.777	Loss
CMGC_DYRK_HIPK_HIPK2_ST	Q9P1Z0	ZBTB4	Q9H2X6	HIPK2	T983	P987L	987	Missense	distal	4	no	119.447	118.447	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	98.777	Down-regulation
CMGC_DYRK_HIPK_HIPK2_ST	Q9P1Z0	ZBTB4	Q9H2X6	HIPK2	T983	P981S	981	Missense	proximal	-2	no	119.447	119.522	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	98.777	Up-regulation
CMGC_DYRK_HIPK_HIPK2_ST	Q01196	RUNX1	Q9H2X6	HIPK2	S292	S295F	295	Missense	distal	3	no	99.133	98.384	EPSD	TCGA;ICGC;COSMIC	98.777	Loss
CMGC_DYRK_HIPK_HIPK2_ST	Q01196	RUNX1	Q9H2X6	HIPK2	S292	P298Q	298	Missense	distal	6	no	99.133	99.086	EPSD	TCGA;ICGC;COSMIC	98.777	Down-regulation
CMGC_DYRK_HIPK_HIPK2_ST	Q01196	RUNX1	Q9H2X6	HIPK2	S435	A440T	440	Missense	distal	5	no	98.927	98.956	EPSD	TCGA;ICGC;COSMIC	98.777	Up-regulation
CMGC_DYRK_HIPK_HIPK2_ST	P57682	KLF3	Q9H2X6	HIPK2	T49	G52D	52	Missense	distal	3	no	117.825	117.570	EPSD	TCGA;ICGC	98.777	Down-regulation
CMGC_DYRK_HIPK_HIPK2_ST	P57682	KLF3	Q9H2X6	HIPK2	S71	P72S	72	Missense	proximal	1	no	114.441	97.161	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	98.777	Loss
CMGC_DYRK_HIPK_HIPK2_ST	P57682	KLF3	Q9H2X6	HIPK2	S71	K68R	68	Missense	distal	-3	no	114.441	114.847	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	98.777	Up-regulation
CMGC_DYRK_HIPK_HIPK2_ST	P57682	KLF3	Q9H2X6	HIPK2	S71	T65M	65	Missense	distal	-6	no	114.441	114.422	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	98.777	Down-regulation
CMGC_DYRK_HIPK_HIPK2_ST	P57682	KLF3	Q9H2X6	HIPK2	S78	P72S	72	Missense	distal	-6	no	118.243	118.249	PhosphoSitePlus;EPSD	TCGA;ICGC;COSMIC	98.777	Up-regulation
CMGC_DYRK_HIPK_HIPK2_ST	P57682	KLF3	Q9H2X6	HIPK2	S92	M97T	97	Missense	distal	5	no	114.986	114.917	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	98.777	Down-regulation
CMGC_DYRK_HIPK_HIPK2_ST	P57682	KLF3	Q9H2X6	HIPK2	S92	R89Q	89	Missense	distal	-3	no	114.986	114.421	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	98.777	Down-regulation
CMGC_DYRK_HIPK_HIPK2_ST	P57682	KLF3	Q9H2X6	HIPK2	S101	M97T	97	Missense	distal	-4	no	121.389	121.664	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	98.777	Up-regulation
CMGC_DYRK_HIPK_HIPK2_ST	P57682	KLF3	Q9H2X6	HIPK2	S101	S100F	100	Missense	proximal	-1	no	121.389	119.126	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC;CCLE	98.777	Down-regulation
CMGC_DYRK_HIPK_HIPK2_ST	P57682	KLF3	Q9H2X6	HIPK2	S101	P103L	103	Missense	proximal	2	no	121.389	119.839	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC;GDSC;CCLE	98.777	Down-regulation
CMGC_DYRK_HIPK_HIPK2_ST	P57682	KLF3	Q9H2X6	HIPK2	S108	P112S	112	Missense	distal	4	no	116.929	118.062	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	98.777	Up-regulation
CMGC_DYRK_HIPK_HIPK2_ST	P57682	KLF3	Q9H2X6	HIPK2	S108	P103L	103	Missense	distal	-5	no	116.929	109.505	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC;GDSC;CCLE	98.777	Down-regulation
CMGC_DYRK_HIPK_HIPK2_ST	P57682	KLF3	Q9H2X6	HIPK2	S111	P112S	112	Missense	proximal	1	no	116.718	99.437	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	98.777	Down-regulation
CMGC_DYRK_HIPK_HIPK2_ST	P57682	KLF3	Q9H2X6	HIPK2	S216	S216P	216	Missense	central	0	yes	117.302	0.000	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	98.777	Loss
CMGC_DYRK_HIPK_HIPK2_ST	P57682	KLF3	Q9H2X6	HIPK2	S224	P225L	225	Missense	proximal	1	no	114.033	-6.252	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	98.777	Loss
CMGC_DYRK_HIPK_HIPK2_ST	P57682	KLF3	Q9H2X6	HIPK2	S224	A228T	228	Missense	distal	4	no	114.033	113.276	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	98.777	Down-regulation
CMGC_DYRK_HIPK_HIPK2_ST	P57682	KLF3	Q9H2X6	HIPK2	S224	S224F	224	Missense	central	0	yes	114.033	0.000	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	98.777	Loss
CMGC_DYRK_HIPK_HIPK2_ST	P57682	KLF3	Q9H2X6	HIPK2	S224	P226L	226	Missense	proximal	2	no	114.033	112.483	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	98.777	Down-regulation
CMGC_DYRK_HIPK_HIPK2_ST	P57682	KLF3	Q9H2X6	HIPK2	S250	R257Q	257	Missense	distal	7	no	119.124	119.606	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	98.777	Up-regulation
CMGC_DYRK_HIPK_HIPK2_ST	P57682	KLF3	Q9H2X6	HIPK2	S250	E249K	249	Missense	proximal	-1	no	119.124	119.097	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	98.777	Down-regulation
CMGC_DYRK_HIPK_HIPK2_ST	P57682	KLF3	Q9H2X6	HIPK2	S250	K243N	243	Missense	distal	-7	no	119.124	118.016	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	98.777	Down-regulation
CMGC_DYRK_HIPK_HIPK2_ST	P57682	KLF3	Q9H2X6	HIPK2	S250	R255M	255	Missense	distal	5	no	119.124	119.164	EPSD;PhosphoSitePlus	TCGA;ICGC	98.777	Up-regulation
CMGC_DYRK_HIPK_HIPK2_ST	Q04724	TLE1	Q9H2X6	HIPK2	S267	N271H	271	Missense	distal	4	no	102.743	98.895	EPSD	TCGA;ICGC;COSMIC	98.777	Down-regulation
CMGC_DYRK_HIPK_HIPK2_ST	Q04724	TLE1	Q9H2X6	HIPK2	S285	P287A	287	Missense	proximal	2	no	104.532	104.657	EPSD	TCGA;ICGC;COSMIC	98.777	Up-regulation
CMGC_DYRK_HIPK_HIPK2_ST	Q04724	TLE1	Q9H2X6	HIPK2	S285	A291T	291	Missense	distal	6	no	104.532	104.405	EPSD	TCGA;ICGC;COSMIC	98.777	Down-regulation
CMGC_DYRK_HIPK_HIPK2_ST	Q04724	TLE1	Q9H2X6	HIPK2	S285	T290M	290	Missense	distal	5	no	104.532	104.601	EPSD	TCGA;ICGC	98.777	Up-regulation
CMGC_DYRK_HIPK_HIPK2_ST	Q04724	TLE1	Q9H2X6	HIPK2	S285	A283V	283	Missense	proximal	-2	no	104.532	104.174	EPSD	TCGA;ICGC;COSMIC	98.777	Down-regulation
CMGC_DYRK_HIPK_HIPK2_ST	Q04724	TLE1	Q9H2X6	HIPK2	S286	S285T	285	Missense	proximal	-1	no	115.686	113.889	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	98.777	Down-regulation
CMGC_DYRK_HIPK_HIPK2_ST	Q04724	TLE1	Q9H2X6	HIPK2	S286	P287A	287	Missense	proximal	1	no	115.686	-12.838	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	98.777	Loss
CMGC_DYRK_HIPK_HIPK2_ST	Q04724	TLE1	Q9H2X6	HIPK2	S286	A291T	291	Missense	distal	5	no	115.686	115.715	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	98.777	Up-regulation
CMGC_DYRK_HIPK_HIPK2_ST	Q04724	TLE1	Q9H2X6	HIPK2	S286	T290M	290	Missense	distal	4	no	115.686	115.494	EPSD;PhosphoSitePlus	TCGA;ICGC	98.777	Down-regulation
CMGC_DYRK_HIPK_HIPK2_ST	Q04724	TLE1	Q9H2X6	HIPK2	S286	A283V	283	Missense	distal	-3	no	115.686	115.909	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	98.777	Up-regulation
CMGC_DYRK_HIPK_HIPK2_ST	Q04724	TLE1	Q9H2X6	HIPK2	T319	R323W	323	Missense	distal	4	no	111.778	102.916	EPSD	TCGA;ICGC;COSMIC	98.777	Down-regulation
CMGC_DYRK_HIPK_HIPK2_ST	Q04724	TLE1	Q9H2X6	HIPK2	T321	R323W	323	Missense	proximal	2	no	112.012	109.668	EPSD	TCGA;ICGC;COSMIC	98.777	Down-regulation
CMGC_DYRK_HIPK_HIPK2_ST	Q04724	TLE1	Q9H2X6	HIPK2	T328	A333T	333	Missense	distal	5	no	118.841	118.870	EPSD	TCGA;ICGC;COSMIC	98.777	Up-regulation
CMGC_DYRK_HIPK_HIPK2_ST	Q04724	TLE1	Q9H2X6	HIPK2	T328	R323W	323	Missense	distal	-5	no	118.841	103.543	EPSD	TCGA;ICGC;COSMIC	98.777	Down-regulation
CMGC_DYRK_HIPK_HIPK2_ST	Q04724	TLE1	Q9H2X6	HIPK2	T334	A333T	333	Missense	proximal	-1	no	116.873	116.151	EPSD	TCGA;ICGC;COSMIC	98.777	Down-regulation
CMGC_DYRK_HIPK_HIPK2_ST	Q04724	TLE1	Q9H2X6	HIPK2	S416	P417L	417	Missense	proximal	1	no	106.834	-13.451	EPSD	TCGA;ICGC;COSMIC	98.777	Loss
CMGC_DYRK_HIPK_HIPK2_ST	Q04724	TLE1	Q9H2X6	HIPK2	S416	A409T	409	Missense	distal	-7	no	106.834	105.306	EPSD	TCGA;ICGC;COSMIC	98.777	Down-regulation
CMGC_DYRK_HIPK_HIPK2_ST	Q04724	TLE1	Q9H2X6	HIPK2	S416	V410A	410	Missense	distal	-6	no	106.834	107.071	EPSD	TCGA;ICGC;COSMIC	98.777	Up-regulation
CMGC_DYRK_HIPK_HIPK2_ST	Q04724	TLE1	Q9H2X6	HIPK2	S416	R415H	415	Missense	proximal	-1	no	106.834	105.543	EPSD	TCGA;ICGC	98.777	Down-regulation
CMGC_DYRK_HIPK_HIPK2_ST	P17096	HMGA1	Q9H2X6	HIPK2	T21	E22Q	22	Missense	proximal	1	no	100.181	63.738	EPSD	TCGA;ICGC;COSMIC	98.777	Loss
CMGC_DYRK_HIPK_HIPK2_ST	P17096	HMGA1	Q9H2X6	HIPK2	T21	R24W	24	Missense	distal	3	no	100.181	99.074	EPSD	TCGA;ICGC;COSMIC	98.777	Down-regulation
CMGC_DYRK_HIPK_HIPK2_ST	P17096	HMGA1	Q9H2X6	HIPK2	S36	A40T	40	Missense	distal	4	no	115.973	115.217	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	98.777	Down-regulation
CMGC_DYRK_HIPK_HIPK2_ST	P17096	HMGA1	Q9H2X6	HIPK2	T53	K55N	55	Missense	proximal	2	no	118.348	118.191	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	98.777	Down-regulation
CMGC_DYRK_HIPK_HIPK2_ST	P17096	HMGA1	Q9H2X6	HIPK2	T53	R58W	58	Missense	distal	5	no	118.348	118.550	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	98.777	Up-regulation
CMGC_DYRK_HIPK_HIPK2_ST	P46531	NOTCH1	Q9H2X6	HIPK2	T1861	S1856F	1856	Missense	distal	-5	no	100.189	98.872	EPSD	TCGA;ICGC;COSMIC	98.777	Down-regulation
CMGC_DYRK_HIPK_HIPK2_ST	P46531	NOTCH1	Q9H2X6	HIPK2	T1861	R1854H	1854	Missense	distal	-7	no	100.189	97.847	EPSD	TCGA;ICGC;COSMIC;GDSC;CCLE	98.777	Loss
CMGC_DYRK_HIPK_HIPK2_ST	P46531	NOTCH1	Q9H2X6	HIPK2	T1861	P1862L	1862	Missense	proximal	1	no	100.189	-20.096	EPSD	TCGA;ICGC;COSMIC	98.777	Loss
CMGC_DYRK_HIPK_HIPK2_ST	P46531	NOTCH1	Q9H2X6	HIPK2	T1997	T1996M	1996	Missense	proximal	-1	no	100.798	101.526	EPSD	TCGA;ICGC;COSMIC;GDSC;CCLE	98.777	Up-regulation
CMGC_DYRK_HIPK_HIPK2_ST	P46531	NOTCH1	Q9H2X6	HIPK2	T1997	H1993Y	1993	Missense	distal	-4	no	100.798	100.946	EPSD	TCGA;ICGC	98.777	Up-regulation
CMGC_DYRK_HIPK_HIPK2_ST	P46531	NOTCH1	Q9H2X6	HIPK2	T1997	T1997M	1997	Missense	central	0	yes	100.798	0.000	EPSD	TCGA;ICGC;COSMIC	98.777	Loss
CMGC_DYRK_HIPK_HIPK2_ST	P46531	NOTCH1	Q9H2X6	HIPK2	S2221	P2222L	2222	Missense	proximal	1	no	105.935	-14.350	EPSD	TCGA;ICGC;COSMIC;CCLE	98.777	Loss
CMGC_DYRK_HIPK_HIPK2_ST	P46531	NOTCH1	Q9H2X6	HIPK2	S2221	P2222S	2222	Missense	proximal	1	no	105.935	88.655	EPSD	TCGA;ICGC;COSMIC	98.777	Loss
CMGC_DYRK_HIPK_HIPK2_ST	P46531	NOTCH1	Q9H2X6	HIPK2	S2221	P2227S	2227	Missense	distal	6	no	105.935	105.847	EPSD	TCGA;ICGC;COSMIC	98.777	Down-regulation
CMGC_DYRK_HIPK_HIPK2_ST	P46531	NOTCH1	Q9H2X6	HIPK2	T2511	P2514T	2514	Missense	distal	3	no	124.756	124.292	PhosphoSitePlus	TCGA;ICGC;COSMIC	98.777	Down-regulation
CMGC_DYRK_HIPK_HIPK2_ST	P46531	NOTCH1	Q9H2X6	HIPK2	S2513	P2514T	2514	Missense	proximal	1	no	119.291	-32.044	EPSD	TCGA;ICGC;COSMIC	98.777	Loss
CMGC_DYRK_HIPK_HIPK2_ST	P46531	NOTCH1	Q9H2X6	HIPK2	S2523	S2521F	2521	Missense	proximal	-2	no	102.633	101.966	EPSD	TCGA;ICGC;COSMIC	98.777	Down-regulation
CMGC_DYRK_HIPK_HIPK2_ST	P46531	NOTCH1	Q9H2X6	HIPK2	S2523	S2523L	2523	Missense	central	0	yes	102.633	0.000	EPSD	TCGA;ICGC;COSMIC;GDSC;CCLE	98.777	Loss
CMGC_DYRK_HIPK_HIPK2_ST	P46531	NOTCH1	Q9H2X6	HIPK2	S2524	S2521F	2521	Missense	distal	-3	no	104.924	105.642	EPSD	TCGA;ICGC;COSMIC	98.777	Up-regulation
CMGC_DYRK_HIPK_HIPK2_ST	P46531	NOTCH1	Q9H2X6	HIPK2	S2524	S2523L	2523	Missense	proximal	-1	no	104.924	103.217	EPSD	TCGA;ICGC;COSMIC;GDSC;CCLE	98.777	Down-regulation
CMGC_DYRK_HIPK_HIPK2_ST	Q13363	CTBP1	Q9H2X6	HIPK2	S100	D106N	106	Missense	distal	6	no	99.339	99.352	EPSD	TCGA;GDSC;CCLE	98.777	Up-regulation
CMGC_DYRK_HIPK_HIPK2_ST	Q13363	CTBP1	Q9H2X6	HIPK2	S100	R97W	97	Missense	distal	-3	no	99.339	100.276	EPSD	TCGA;COSMIC	98.777	Up-regulation
CMGC_DYRK_HIPK_HIPK2_ST	Q13363	CTBP1	Q9H2X6	HIPK2	S100	R93H	93	Missense	distal	-7	no	99.339	96.998	EPSD	TCGA;COSMIC	98.777	Loss
CMGC_DYRK_HIPK_HIPK2_ST	Q13363	CTBP1	Q9H2X6	HIPK2	S100	V96I	96	Missense	distal	-4	no	99.339	99.494	EPSD	TCGA	98.777	Up-regulation
CMGC_DYRK_HIPK_HIPK2_ST	Q13363	CTBP1	Q9H2X6	HIPK2	S422	V427G	427	Missense	distal	5	no	114.919	114.882	PhosphoSitePlus	TCGA;COSMIC	98.777	Down-regulation
CMGC_DYRK_HIPK_HIPK2_ST	P29590	PML	Q9H2X6	HIPK2	S40	A47T	47	Missense	distal	7	no	116.446	116.539	EPSD	TCGA;ICGC;COSMIC	98.777	Up-regulation
CMGC_DYRK_HIPK_HIPK2_ST	P29590	PML	Q9H2X6	HIPK2	T42	S48L	48	Missense	distal	6	no	102.550	102.266	EPSD	TCGA;ICGC;COSMIC	98.777	Down-regulation
CMGC_DYRK_HIPK_HIPK2_ST	P29590	PML	Q9H2X6	HIPK2	T42	A47T	47	Missense	distal	5	no	102.550	102.579	EPSD	TCGA;ICGC;COSMIC	98.777	Up-regulation
CMGC_DYRK_HIPK_HIPK2_ST	P29590	PML	Q9H2X6	HIPK2	S403	P410S	410	Missense	distal	7	no	106.259	106.299	EPSD	TCGA;ICGC;COSMIC	98.777	Up-regulation
CMGC_DYRK_HIPK_HIPK2_ST	P29590	PML	Q9H2X6	HIPK2	S403	E405K	405	Missense	proximal	2	no	106.259	105.219	EPSD	TCGA;ICGC	98.777	Down-regulation
CMGC_DYRK_HIPK_HIPK2_ST	P29590	PML	Q9H2X6	HIPK2	T409	P410S	410	Missense	proximal	1	no	115.765	98.484	EPSD	TCGA;ICGC;COSMIC	98.777	Loss
CMGC_DYRK_HIPK_HIPK2_ST	P29590	PML	Q9H2X6	HIPK2	T409	E405K	405	Missense	distal	-4	no	115.765	115.840	EPSD	TCGA;ICGC	98.777	Up-regulation
CMGC_DYRK_HIPK_HIPK2_ST	P29590	PML	Q9H2X6	HIPK2	T409	P413L	413	Missense	distal	4	no	115.765	114.765	EPSD	TCGA;ICGC;COSMIC	98.777	Down-regulation
CMGC_DYRK_HIPK_HIPK2_ST	P29590	PML	Q9H2X6	HIPK2	S505	L501F	501	Missense	distal	-4	no	102.426	102.235	EPSD	TCGA;ICGC;COSMIC	98.777	Down-regulation
CMGC_DYRK_HIPK_HIPK2_ST	P29590	PML	Q9H2X6	HIPK2	S518	S518L	518	Missense	central	0	yes	111.531	0.000	EPSD	TCGA;ICGC;COSMIC	98.777	Loss
CMGC_DYRK_HIPK_HIPK2_ST	P29590	PML	Q9H2X6	HIPK2	S560	S561N	561	Missense	proximal	1	no	104.125	71.173	EPSD	TCGA;ICGC;COSMIC	98.777	Loss
CMGC_DYRK_HIPK_HIPK2_ST	P29590	PML	Q9H2X6	HIPK2	S560	V556I	556	Missense	distal	-4	no	104.125	104.279	EPSD	TCGA;ICGC;COSMIC	98.777	Up-regulation
CMGC_DYRK_HIPK_HIPK2_ST	P29590	PML	Q9H2X6	HIPK2	S561	E568K	568	Missense	distal	7	no	104.036	103.850	EPSD	TCGA;ICGC;COSMIC	98.777	Down-regulation
CMGC_DYRK_HIPK_HIPK2_ST	P29590	PML	Q9H2X6	HIPK2	S561	S561N	561	Missense	central	0	yes	104.036	0.000	EPSD	TCGA;ICGC;COSMIC	98.777	Loss
CMGC_DYRK_HIPK_HIPK2_ST	P29590	PML	Q9H2X6	HIPK2	S561	V556I	556	Missense	distal	-5	no	104.036	107.278	EPSD	TCGA;ICGC;COSMIC	98.777	Up-regulation
CMGC_DYRK_HIPK_HIPK2_ST	P51608	MECP2	Q9H2X6	HIPK2	T64	A62G	62	Missense	proximal	-2	no	100.444	100.615	EPSD	TCGA;COSMIC	98.777	Up-regulation
CMGC_DYRK_HIPK_HIPK2_ST	P51608	MECP2	Q9H2X6	HIPK2	S68	A62G	62	Missense	distal	-6	no	104.164	104.176	EPSD	TCGA;COSMIC	98.777	Up-regulation
CMGC_DYRK_HIPK_HIPK2_ST	P51608	MECP2	Q9H2X6	HIPK2	S291	V288M	288	Missense	distal	-3	no	99.251	99.073	EPSD	TCGA;ICGC;COSMIC	98.777	Down-regulation
CMGC_DYRK_HIPK_HIPK2_ST	P04637	TP53	Q9H2X6	HIPK2	S33	P27S	27	Missense	distal	-6	no	103.633	103.639	EPSD	TCGA;ICGC;COSMIC	98.777	Up-regulation
CMGC_DYRK_HIPK_HIPK2_ST	P04637	TP53	Q9H2X6	HIPK2	S33	P27L	27	Missense	distal	-6	no	103.633	103.497	EPSD	TCGA;ICGC;COSMIC;GDSC;CCLE	98.777	Down-regulation
CMGC_DYRK_HIPK_HIPK2_ST	P04637	TP53	Q9H2X6	HIPK2	S46	D48N	48	Missense	proximal	2	no	116.500	117.072	PhosphoSitePlus	TCGA;ICGC;COSMIC;GDSC;CCLE	98.777	Up-regulation
CMGC_DYRK_HIPK_HIPK2_ST	P04637	TP53	Q9H2X6	HIPK2	S127	N131S	131	Missense	distal	4	no	96.897	99.583	EPSD	TCGA;ICGC;COSMIC	98.777	Gain
CMGC_DYRK_HIPK_HIPK2_ST	P04637	TP53	Q9H2X6	HIPK2	S127	N131I	131	Missense	distal	4	no	96.897	98.793	EPSD	TCGA;ICGC;COSMIC	98.777	Gain
CMGC_DYRK_HIPK_HIPK2_ST	P04637	TP53	Q9H2X6	HIPK2	T150	W146S	146	Missense	distal	-4	no	104.776	105.332	EPSD	TCGA;ICGC;COSMIC	98.777	Up-regulation
CMGC_DYRK_HIPK_HIPK2_ST	P04637	TP53	Q9H2X6	HIPK2	T150	P152L	152	Missense	proximal	2	no	104.776	103.227	EPSD	TCGA;ICGC;COSMIC;GDSC;CCLE	98.777	Down-regulation
CMGC_DYRK_HIPK_HIPK2_ST	P04637	TP53	Q9H2X6	HIPK2	T150	D148N	148	Missense	proximal	-2	no	104.776	104.850	EPSD	TCGA;ICGC;COSMIC	98.777	Up-regulation
CMGC_DYRK_HIPK_HIPK2_ST	P04637	TP53	Q9H2X6	HIPK2	T150	P151H	151	Missense	proximal	1	no	104.776	-7.278	EPSD	TCGA;ICGC;COSMIC;GDSC;CCLE	98.777	Loss
CMGC_DYRK_HIPK_HIPK2_ST	P04637	TP53	Q9H2X6	HIPK2	T150	P151A	151	Missense	proximal	1	no	104.776	-23.748	EPSD	TCGA;ICGC;COSMIC;CCLE	98.777	Loss
CMGC_DYRK_HIPK_HIPK2_ST	P04637	TP53	Q9H2X6	HIPK2	T150	R156P	156	Missense	distal	6	no	104.776	105.305	EPSD	TCGA;ICGC;COSMIC;GDSC;CCLE	98.777	Up-regulation
CMGC_DYRK_HIPK_HIPK2_ST	P04637	TP53	Q9H2X6	HIPK2	T150	V143A	143	Missense	distal	-7	no	104.776	105.785	EPSD	TCGA;ICGC;COSMIC;GDSC;CCLE	98.777	Up-regulation
CMGC_DYRK_HIPK_HIPK2_ST	P04637	TP53	Q9H2X6	HIPK2	T150	P151S	151	Missense	proximal	1	no	104.776	87.496	EPSD	TCGA;ICGC;COSMIC;GDSC;CCLE	98.777	Loss
CMGC_DYRK_HIPK_HIPK2_ST	P04637	TP53	Q9H2X6	HIPK2	T150	V157F	157	Missense	distal	7	no	104.776	104.675	EPSD	TCGA;ICGC;COSMIC;GDSC;CCLE	98.777	Down-regulation
CMGC_DYRK_HIPK_HIPK2_ST	P04637	TP53	Q9H2X6	HIPK2	T150	V157G	157	Missense	distal	7	no	104.776	104.808	EPSD	TCGA;ICGC;COSMIC	98.777	Up-regulation
CMGC_DYRK_HIPK_HIPK2_ST	P04637	TP53	Q9H2X6	HIPK2	T150	V157D	157	Missense	distal	7	no	104.776	104.973	EPSD	TCGA;ICGC;COSMIC	98.777	Up-regulation
CMGC_DYRK_HIPK_HIPK2_ST	P04637	TP53	Q9H2X6	HIPK2	T150	L145R	145	Missense	distal	-5	no	104.776	110.417	EPSD	TCGA;ICGC;COSMIC;GDSC;CCLE	98.777	Up-regulation
CMGC_DYRK_HIPK_HIPK2_ST	P04637	TP53	Q9H2X6	HIPK2	T150	T155I	155	Missense	distal	5	no	104.776	104.683	EPSD	TCGA;ICGC;COSMIC;CCLE	98.777	Down-regulation
CMGC_DYRK_HIPK_HIPK2_ST	P04637	TP53	Q9H2X6	HIPK2	T150	V143M	143	Missense	distal	-7	no	104.776	104.071	EPSD	TCGA;ICGC;COSMIC;GDSC;CCLE	98.777	Down-regulation
CMGC_DYRK_HIPK_HIPK2_ST	P04637	TP53	Q9H2X6	HIPK2	T150	T155N	155	Missense	distal	5	no	104.776	104.759	EPSD	TCGA;ICGC;COSMIC;GDSC;CCLE	98.777	Down-regulation
CMGC_DYRK_HIPK_HIPK2_ST	P04637	TP53	Q9H2X6	HIPK2	T150	P152S	152	Missense	proximal	2	no	104.776	104.741	EPSD	TCGA;ICGC;COSMIC;CCLE	98.777	Down-regulation
CMGC_DYRK_HIPK_HIPK2_ST	P04637	TP53	Q9H2X6	HIPK2	T150	R156C	156	Missense	distal	6	no	104.776	104.308	EPSD	TCGA;ICGC;COSMIC	98.777	Down-regulation
CMGC_DYRK_HIPK_HIPK2_ST	P04637	TP53	Q9H2X6	HIPK2	T150	P151T	151	Missense	proximal	1	no	104.776	-46.559	EPSD	TCGA;ICGC;COSMIC	98.777	Loss
CMGC_DYRK_HIPK_HIPK2_ST	P04637	TP53	Q9H2X6	HIPK2	T150	T155P	155	Missense	distal	5	no	104.776	104.646	EPSD	TCGA;ICGC;COSMIC;CCLE	98.777	Down-regulation
CMGC_DYRK_HIPK_HIPK2_ST	P04637	TP53	Q9H2X6	HIPK2	T150	V143G	143	Missense	distal	-7	no	104.776	105.243	EPSD	TCGA;ICGC;COSMIC	98.777	Up-regulation
CMGC_DYRK_HIPK_HIPK2_ST	P04637	TP53	Q9H2X6	HIPK2	T150	P152Q	152	Missense	proximal	2	no	104.776	104.509	EPSD	TCGA;ICGC;COSMIC	98.777	Down-regulation
CMGC_DYRK_HIPK_HIPK2_ST	P04637	TP53	Q9H2X6	HIPK2	T150	R156H	156	Missense	distal	6	no	104.776	104.458	EPSD	TCGA;ICGC;COSMIC	98.777	Down-regulation
CMGC_DYRK_HIPK_HIPK2_ST	P04637	TP53	Q9H2X6	HIPK2	T150	L145P	145	Missense	distal	-5	no	104.776	112.200	EPSD	TCGA;ICGC;COSMIC	98.777	Up-regulation
CMGC_DYRK_HIPK_HIPK2_ST	P04637	TP53	Q9H2X6	HIPK2	T150	Q144L	144	Missense	distal	-6	no	104.776	104.421	EPSD	TCGA;ICGC;COSMIC	98.777	Down-regulation
CMGC_DYRK_HIPK_HIPK2_ST	P04637	TP53	Q9H2X6	HIPK2	T150	Q144H	144	Missense	distal	-6	no	104.776	104.116	EPSD	TCGA;ICGC;COSMIC	98.777	Down-regulation
CMGC_DYRK_HIPK_HIPK2_ST	P04637	TP53	Q9H2X6	HIPK2	T150	G154V	154	Missense	distal	4	no	104.776	100.719	EPSD	TCGA;ICGC;COSMIC;GDSC;CCLE	98.777	Down-regulation
CMGC_DYRK_HIPK_HIPK2_ST	P04637	TP53	Q9H2X6	HIPK2	T150	V157L	157	Missense	distal	7	no	104.776	105.017	EPSD	TCGA;ICGC;COSMIC	98.777	Up-regulation
CMGC_DYRK_HIPK_HIPK2_ST	P04637	TP53	Q9H2X6	HIPK2	T150	P151R	151	Missense	proximal	1	no	104.776	92.240	EPSD	TCGA;ICGC;COSMIC	98.777	Loss
CMGC_DYRK_HIPK_HIPK2_ST	P04637	TP53	Q9H2X6	HIPK2	T150	Q144P	144	Missense	distal	-6	no	104.776	104.557	EPSD	TCGA;ICGC;COSMIC	98.777	Down-regulation
CMGC_DYRK_HIPK_HIPK2_ST	P04637	TP53	Q9H2X6	HIPK2	T150	V143E	143	Missense	distal	-7	no	104.776	106.036	EPSD	TCGA;ICGC;COSMIC	98.777	Up-regulation
CMGC_DYRK_HIPK_HIPK2_ST	P04637	TP53	Q9H2X6	HIPK2	T150	R156G	156	Missense	distal	6	no	104.776	104.989	EPSD	TCGA;ICGC;COSMIC	98.777	Up-regulation
CMGC_DYRK_HIPK_HIPK2_ST	P04637	TP53	Q9H2X6	HIPK2	T150	P151L	151	Missense	proximal	1	no	104.776	-15.509	EPSD	TCGA;ICGC;COSMIC	98.777	Loss
CMGC_DYRK_HIPK_HIPK2_ST	P04637	TP53	Q9H2X6	HIPK2	T155	R156P	156	Missense	proximal	1	no	92.229	104.765	EPSD	TCGA;ICGC;COSMIC;GDSC;CCLE	98.777	Gain
CMGC_DYRK_HIPK_HIPK2_ST	P04637	TP53	Q9H2X6	HIPK2	S314	K319N	319	Missense	distal	5	no	99.315	99.366	EPSD	TCGA;ICGC;COSMIC	98.777	Up-regulation
CMGC_DYRK_HIPK_HIPK2_ST	P04637	TP53	Q9H2X6	HIPK2	S314	A307V	307	Missense	distal	-7	no	99.315	98.306	EPSD	TCGA;ICGC;COSMIC;GDSC	98.777	Loss
CMGC_DYRK_HIPK_HIPK2_ST	P04637	TP53	Q9H2X6	HIPK2	S314	K320E	320	Missense	distal	6	no	99.315	99.687	EPSD	TCGA;ICGC;COSMIC	98.777	Up-regulation
CMGC_DYRK_HIPK_HIPK2_ST	P04637	TP53	Q9H2X6	HIPK2	S314	S315C	315	Missense	proximal	1	no	99.315	-11.924	EPSD	TCGA;ICGC;COSMIC	98.777	Loss
CMGC_DYRK_HIPK_HIPK2_ST	P04637	TP53	Q9H2X6	HIPK2	S315	K319N	319	Missense	distal	4	no	106.507	103.377	EPSD	TCGA;ICGC;COSMIC	98.777	Down-regulation
CMGC_DYRK_HIPK_HIPK2_ST	P04637	TP53	Q9H2X6	HIPK2	S315	K320E	320	Missense	distal	5	no	106.507	106.443	EPSD	TCGA;ICGC;COSMIC	98.777	Down-regulation
CMGC_DYRK_HIPK_HIPK2_ST	P04637	TP53	Q9H2X6	HIPK2	S315	S315C	315	Missense	central	0	yes	106.507	0.000	EPSD	TCGA;ICGC;COSMIC	98.777	Loss
CMGC_DYRK_HIPK_HIPK2_ST	P04637	TP53	Q9H2X6	HIPK2	S362	A355T	355	Missense	distal	-7	no	100.771	99.244	EPSD	TCGA;ICGC;COSMIC	98.777	Down-regulation
CMGC_DYRK_HIPK_HIPK2_ST	O15297	PPM1D	Q9H2X6	HIPK2	T529	R528I	528	Missense	proximal	-1	no	112.788	113.323	EPSD	TCGA;ICGC;COSMIC	98.777	Up-regulation
CMGC_DYRK_HIPK_HIPK2_ST	O15297	PPM1D	Q9H2X6	HIPK2	S559	R552Q	552	Missense	distal	-7	no	104.541	105.668	EPSD	TCGA;ICGC;COSMIC	98.777	Up-regulation
CMGC_DYRK_HIPK_HIPK2_ST	Q96EB6	SIRT1	Q9H2X6	HIPK2	T177	R181W	181	Missense	distal	4	no	98.856	89.994	EPSD	TCGA;COSMIC;GDSC	98.777	Loss
CMGC_DYRK_HIPK_HIPK2_ST	Q96EB6	SIRT1	Q9H2X6	HIPK2	S540	R543I	543	Missense	distal	3	no	106.061	106.127	EPSD	TCGA;COSMIC	98.777	Up-regulation
CMGC_DYRK_HIPK_HIPK2_ST	Q96EB6	SIRT1	Q9H2X6	HIPK2	S545	S549F	549	Missense	distal	4	no	108.033	101.956	EPSD	TCGA;COSMIC	98.777	Down-regulation
CMGC_DYRK_HIPK_HIPK2_ST	Q96EB6	SIRT1	Q9H2X6	HIPK2	S545	R543I	543	Missense	proximal	-2	no	108.033	108.204	EPSD	TCGA;COSMIC	98.777	Up-regulation
CMGC_DYRK_HIPK_HIPK2_ST	Q96EB6	SIRT1	Q9H2X6	HIPK2	S682	Q681H	681	Missense	proximal	-1	no	119.031	116.702	PhosphoSitePlus;EPSD	TCGA;COSMIC	98.777	Down-regulation
CMGC_DYRK_HIPK_HIPK2_ST	Q96EB6	SIRT1	Q9H2X6	HIPK2	S682	S675N	675	Missense	distal	-7	no	119.031	119.229	PhosphoSitePlus;EPSD	TCGA;COSMIC	98.777	Up-regulation
CMGC_DYRK_HIPK_HIPK2_ST	Q9H2X6	HIPK2	Q9H2X6	HIPK2	S294	K292R	292	Missense	proximal	-2	no	105.124	104.789	EPSD	TCGA;ICGC;COSMIC	98.777	Down-regulation
CMGC_DYRK_HIPK_HIPK2_ST	Q9H2X6	HIPK2	Q9H2X6	HIPK2	S294	P297L	297	Missense	distal	3	no	105.124	104.900	EPSD	TCGA;ICGC;COSMIC	98.777	Down-regulation
CMGC_DYRK_HIPK_HIPK2_ST	Q9H2X6	HIPK2	Q9H2X6	HIPK2	S364	E371Q	371	Missense	distal	7	no	111.696	111.512	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	98.777	Down-regulation
CMGC_DYRK_HIPK_HIPK2_ST	Q9H2X6	HIPK2	Q9H2X6	HIPK2	S364	P370S	370	Missense	distal	6	no	111.696	111.608	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	98.777	Down-regulation
CMGC_DYRK_HIPK_HIPK2_ST	Q9H2X6	HIPK2	Q9H2X6	HIPK2	S441	P444S	444	Missense	distal	3	no	106.073	106.386	EPSD	TCGA;ICGC;COSMIC	98.777	Up-regulation
CMGC_DYRK_HIPK_HIPK2_ST	Q9H2X6	HIPK2	Q9H2X6	HIPK2	S441	D438G	438	Missense	distal	-3	no	106.073	105.931	EPSD	TCGA;ICGC;COSMIC	98.777	Down-regulation
CMGC_DYRK_HIPK_HIPK2_ST	Q9H2X6	HIPK2	Q9H2X6	HIPK2	S441	R437C	437	Missense	distal	-4	no	106.073	105.695	EPSD	TCGA;ICGC;COSMIC	98.777	Down-regulation
CMGC_DYRK_HIPK_HIPK2_ST	Q9H2X6	HIPK2	Q9H2X6	HIPK2	T566	F568L	568	Missense	proximal	2	no	101.793	103.170	EPSD	TCGA;ICGC	98.777	Up-regulation
CMGC_DYRK_HIPK_HIPK2_ST	Q9H2X6	HIPK2	Q9H2X6	HIPK2	T838	R841C	841	Missense	distal	3	no	99.480	98.299	EPSD	TCGA;ICGC;COSMIC	98.777	Loss
CMGC_DYRK_HIPK_HIPK2_ST	Q9H2X6	HIPK2	Q9H2X6	HIPK2	T880	P878L	878	Missense	proximal	-2	no	121.162	120.908	PhosphoSitePlus;EPSD	TCGA;ICGC;COSMIC	98.777	Down-regulation
CMGC_DYRK_HIPK_HIPK2_ST	Q9H2X6	HIPK2	Q9H2X6	HIPK2	S882	T889A	889	Missense	distal	7	no	118.885	118.792	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	98.777	Down-regulation
CMGC_DYRK_HIPK_HIPK2_ST	Q9H2X6	HIPK2	Q9H2X6	HIPK2	S882	I888N	888	Missense	distal	6	no	118.885	118.876	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	98.777	Down-regulation
CMGC_DYRK_HIPK_HIPK2_ST	Q9H2X6	HIPK2	Q9H2X6	HIPK2	S882	P878L	878	Missense	distal	-4	no	118.885	118.748	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	98.777	Down-regulation
CMGC_DYRK_HIPK_HIPK2_ST	Q9H2X6	HIPK2	Q9H2X6	HIPK2	S924	S927F	927	Missense	distal	3	no	102.872	102.124	EPSD	TCGA;ICGC;COSMIC	98.777	Down-regulation
CMGC_DYRK_HIPK_HIPK2_ST	Q9H2X6	HIPK2	Q9H2X6	HIPK2	S934	R941L	941	Missense	distal	7	no	105.408	105.795	EPSD	TCGA;ICGC;COSMIC	98.777	Up-regulation
CMGC_DYRK_HIPK_HIPK2_ST	Q9H2X6	HIPK2	Q9H2X6	HIPK2	S934	S927F	927	Missense	distal	-7	no	105.408	103.466	EPSD	TCGA;ICGC;COSMIC	98.777	Down-regulation
CMGC_DYRK_HIPK_HIPK2_ST	Q9H2X6	HIPK2	Q9H2X6	HIPK2	S934	S937F	937	Missense	distal	3	no	105.408	104.659	EPSD	TCGA;ICGC;COSMIC;CCLE	98.777	Down-regulation
CMGC_DYRK_HIPK_HIPK2_ST	Q9H2X6	HIPK2	Q9H2X6	HIPK2	S934	R941H	941	Missense	distal	7	no	105.408	105.313	EPSD	TCGA;ICGC;COSMIC;CCLE	98.777	Down-regulation
CMGC_DYRK_HIPK_HIPK2_ST	Q9H2X6	HIPK2	Q9H2X6	HIPK2	S1018	R1024W	1024	Missense	distal	6	no	103.681	103.044	EPSD	TCGA;ICGC	98.777	Down-regulation
CMGC_DYRK_HIPK_HIPK2_ST	Q9H2X6	HIPK2	Q9H2X6	HIPK2	T1114	V1117M	1117	Missense	distal	3	no	99.866	99.811	EPSD	TCGA;ICGC;COSMIC	98.777	Down-regulation
CMGC_DYRK_HIPK_HIPK2_ST	Q9H2X6	HIPK2	Q9H2X6	HIPK2	T1114	A1107V	1107	Missense	distal	-7	no	99.866	98.857	EPSD	TCGA;ICGC;COSMIC	98.777	Down-regulation
CMGC_DYRK_HIPK_HIPK2_ST	Q9H2X6	HIPK2	Q9H2X6	HIPK2	T1114	H1119Y	1119	Missense	distal	5	no	99.866	99.808	EPSD	TCGA;ICGC;COSMIC	98.777	Down-regulation
CMGC_DYRK_HIPK_HIPK2_ST	P46527	CDKN1B	Q9H2X6	HIPK2	S10	S7C	7	Missense	distal	-3	no	103.610	104.644	PhosphoSitePlus	TCGA;ICGC;COSMIC	98.777	Up-regulation
CMGC_DYRK_HIPK_HIPK2_ST	P46527	CDKN1B	Q9H2X6	HIPK2	S10	G9W	9	Missense	proximal	-1	no	103.610	100.242	PhosphoSitePlus	TCGA;ICGC;COSMIC	98.777	Down-regulation
CMGC_DYRK_HIPK_HIPK2_ST	P46527	CDKN1B	Q9H2X6	HIPK2	S110	A116S	116	Missense	distal	6	no	108.233	108.200	EPSD	TCGA;ICGC;COSMIC	98.777	Down-regulation
CMGC_DYRK_HIPK_HIPK2_ST	P46527	CDKN1B	Q9H2X6	HIPK2	S110	A103V	103	Missense	distal	-7	no	108.233	107.224	EPSD	TCGA;ICGC	98.777	Down-regulation
CMGC_DYRK_HIPK_HIPK2_ST	P46527	CDKN1B	Q9H2X6	HIPK2	S112	A116S	116	Missense	distal	4	no	103.876	104.877	EPSD	TCGA;ICGC;COSMIC	98.777	Up-regulation
CMGC_DYRK_HIPK_HIPK2_ST	P46527	CDKN1B	Q9H2X6	HIPK2	T142	E146K	146	Missense	distal	4	no	108.563	109.041	EPSD	TCGA;ICGC;COSMIC	98.777	Up-regulation
CMGC_DYRK_HIPK_HIPK2_ST	O00257	CBX4	Q9H2X6	HIPK2	S147	K149N	149	Missense	proximal	2	no	102.564	102.406	EPSD	TCGA;ICGC;COSMIC	98.777	Down-regulation
CMGC_DYRK_HIPK_HIPK2_ST	O00257	CBX4	Q9H2X6	HIPK2	S147	K140N	140	Missense	distal	-7	no	102.564	101.456	EPSD	TCGA;ICGC;COSMIC	98.777	Down-regulation
CMGC_DYRK_HIPK_HIPK2_ST	O00257	CBX4	Q9H2X6	HIPK2	S182	H177R	177	Missense	distal	-5	no	97.734	108.569	EPSD	TCGA;ICGC;COSMIC	98.777	Gain
CMGC_DYRK_HIPK_HIPK2_ST	O00257	CBX4	Q9H2X6	HIPK2	S291	K295N	295	Missense	distal	4	no	111.295	108.166	EPSD	TCGA;ICGC;COSMIC	98.777	Down-regulation
CMGC_DYRK_HIPK_HIPK2_ST	O00257	CBX4	Q9H2X6	HIPK2	S291	R290C	290	Missense	proximal	-1	no	111.295	109.426	EPSD	TCGA;ICGC;COSMIC	98.777	Down-regulation
CMGC_DYRK_HIPK_HIPK2_ST	O00257	CBX4	Q9H2X6	HIPK2	S291	R297Q	297	Missense	distal	6	no	111.295	111.778	EPSD	TCGA;ICGC;COSMIC	98.777	Up-regulation
CMGC_DYRK_HIPK_HIPK2_ST	O00257	CBX4	Q9H2X6	HIPK2	S333	G334R	334	Missense	proximal	1	no	103.909	102.506	EPSD	TCGA;ICGC;COSMIC;CCLE	98.777	Down-regulation
CMGC_DYRK_HIPK_HIPK2_ST	O00257	CBX4	Q9H2X6	HIPK2	S333	P338S	338	Missense	distal	5	no	103.909	103.910	EPSD	TCGA;ICGC;COSMIC	98.777	Up-regulation
CMGC_DYRK_HIPK_HIPK2_ST	O00257	CBX4	Q9H2X6	HIPK2	S333	P338L	338	Missense	distal	5	no	103.909	104.022	EPSD	TCGA;ICGC;COSMIC	98.777	Up-regulation
CMGC_DYRK_HIPK_HIPK2_ST	O00257	CBX4	Q9H2X6	HIPK2	S333	R328M	328	Missense	distal	-5	no	103.909	97.248	EPSD	TCGA;ICGC;COSMIC	98.777	Loss
CMGC_DYRK_HIPK_HIPK2_ST	O00257	CBX4	Q9H2X6	HIPK2	S345	P338S	338	Missense	distal	-7	no	104.813	104.162	EPSD	TCGA;ICGC;COSMIC	98.777	Down-regulation
CMGC_DYRK_HIPK_HIPK2_ST	O00257	CBX4	Q9H2X6	HIPK2	S345	P350L	350	Missense	distal	5	no	104.813	104.926	EPSD	TCGA;ICGC;COSMIC	98.777	Up-regulation
CMGC_DYRK_HIPK_HIPK2_ST	O00257	CBX4	Q9H2X6	HIPK2	S345	P338L	338	Missense	distal	-7	no	104.813	103.727	EPSD	TCGA;ICGC;COSMIC	98.777	Down-regulation
CMGC_DYRK_HIPK_HIPK2_ST	O00257	CBX4	Q9H2X6	HIPK2	S349	P350L	350	Missense	proximal	1	no	110.746	-9.539	EPSD	TCGA;ICGC;COSMIC	98.777	Loss
CMGC_DYRK_HIPK_HIPK2_ST	O00257	CBX4	Q9H2X6	HIPK2	T435	C438F	438	Missense	distal	3	no	102.901	103.723	EPSD	TCGA;ICGC;COSMIC	98.777	Up-regulation
CMGC_DYRK_HIPK_HIPK2_ST	O00257	CBX4	Q9H2X6	HIPK2	S442	C438F	438	Missense	distal	-4	no	109.811	110.121	EPSD	TCGA;ICGC;COSMIC	98.777	Up-regulation
CMGC_DYRK_HIPK_HIPK2_ST	O00257	CBX4	Q9H2X6	HIPK2	T480	E486K	486	Missense	distal	6	no	99.429	99.057	EPSD	TCGA;ICGC;COSMIC	98.777	Down-regulation
CMGC_DYRK_HIPK_HIPK2_ST	O00257	CBX4	Q9H2X6	HIPK2	T480	D474G	474	Missense	distal	-6	no	99.429	99.315	EPSD	TCGA;ICGC;COSMIC	98.777	Down-regulation
CMGC_DYRK_HIPK_HIPK2_ST	O00257	CBX4	Q9H2X6	HIPK2	T497	A504V	504	Missense	distal	7	no	120.888	120.561	PhosphoSitePlus	TCGA;ICGC;COSMIC	98.777	Down-regulation
CMGC_DYRK_HIPK_HIPK2_ST	P16220	CREB1	Q9H2X6	HIPK2	S129	L128I	128	Missense	proximal	-1	no	101.576	102.290	EPSD	TCGA;COSMIC	98.777	Up-regulation
CMGC_DYRK_HIPK_HIPK2_ST	O43255	SIAH2	Q9H2X6	HIPK2	T254	L251F	251	Missense	distal	-3	no	100.699	101.017	EPSD	TCGA;ICGC;COSMIC	98.777	Up-regulation
CMGC_DYRK_HIPK_HIPK2_ST	O43255	SIAH2	Q9H2X6	HIPK2	T254	F261V	261	Missense	distal	7	no	100.699	100.800	EPSD	TCGA;ICGC;COSMIC	98.777	Up-regulation
CMGC_DYRK_HIPK_HIPK2_ST	O43255	SIAH2	Q9H2X6	HIPK2	T254	E259K	259	Missense	distal	5	no	100.699	100.762	EPSD	TCGA;ICGC	98.777	Up-regulation
CMGC_DYRK_HIPK_HIPK2_ST	Q9H3D4	TP63	Q9H2X6	HIPK2	S160	P166L	166	Missense	distal	6	no	104.093	103.720	EPSD	TCGA;ICGC;COSMIC	98.777	Down-regulation
CMGC_DYRK_HIPK_HIPK2_ST	Q9H3D4	TP63	Q9H2X6	HIPK2	S160	A164T	164	Missense	distal	4	no	104.093	103.336	EPSD	TCGA;COSMIC	98.777	Down-regulation
CMGC_DYRK_HIPK_HIPK2_ST	Q9H3D4	TP63	Q9H2X6	HIPK2	S160	A164V	164	Missense	distal	4	no	104.093	101.110	EPSD	TCGA;ICGC;COSMIC	98.777	Down-regulation
CMGC_DYRK_HIPK_HIPK2_ST	Q9H3D4	TP63	Q9H2X6	HIPK2	S160	P163L	163	Missense	distal	3	no	104.093	103.869	EPSD	TCGA;ICGC;COSMIC	98.777	Down-regulation
CMGC_DYRK_HIPK_HIPK2_ST	Q9H3D4	TP63	Q9H2X6	HIPK2	S160	S153R	153	Missense	distal	-7	no	104.093	103.860	EPSD	TCGA;ICGC;COSMIC	98.777	Down-regulation
CMGC_DYRK_HIPK_HIPK2_ST	Q9H3D4	TP63	Q9H2X6	HIPK2	S160	D157Y	157	Missense	distal	-3	no	104.093	104.508	EPSD	TCGA;ICGC;COSMIC	98.777	Up-regulation
CMGC_DYRK_HIPK_HIPK2_ST	Q9H3D4	TP63	Q9H2X6	HIPK2	S162	P166L	166	Missense	distal	4	no	117.768	116.768	EPSD	TCGA;ICGC;COSMIC	98.777	Down-regulation
CMGC_DYRK_HIPK_HIPK2_ST	Q9H3D4	TP63	Q9H2X6	HIPK2	S162	A164T	164	Missense	proximal	2	no	117.768	117.065	EPSD	TCGA;COSMIC	98.777	Down-regulation
CMGC_DYRK_HIPK_HIPK2_ST	Q9H3D4	TP63	Q9H2X6	HIPK2	S162	A164V	164	Missense	proximal	2	no	117.768	116.176	EPSD	TCGA;ICGC;COSMIC	98.777	Down-regulation
CMGC_DYRK_HIPK_HIPK2_ST	Q9H3D4	TP63	Q9H2X6	HIPK2	S162	P163L	163	Missense	proximal	1	no	117.768	-2.517	EPSD	TCGA;ICGC;COSMIC	98.777	Loss
CMGC_DYRK_HIPK_HIPK2_ST	Q9H3D4	TP63	Q9H2X6	HIPK2	S162	D157Y	157	Missense	distal	-5	no	117.768	113.471	EPSD	TCGA;ICGC;COSMIC	98.777	Down-regulation
CMGC_DYRK_HIPK_HIPK2_ST	Q9H3D4	TP63	Q9H2X6	HIPK2	S395	P396T	396	Missense	proximal	1	no	106.730	-44.605	EPSD	TCGA;COSMIC	98.777	Loss
CMGC_DYRK_HIPK_HIPK2_ST	Q9H3D4	TP63	Q9H2X6	HIPK2	S395	T388I	388	Missense	distal	-7	no	106.730	107.143	EPSD	TCGA;ICGC;COSMIC	98.777	Up-regulation
CMGC_DYRK_HIPK_HIPK2_ST	Q9H3D4	TP63	Q9H2X6	HIPK2	S395	D398N	398	Missense	distal	3	no	106.730	107.043	EPSD	TCGA;ICGC;COSMIC	98.777	Up-regulation
CMGC_DYRK_HIPK_HIPK2_ST	Q9H3D4	TP63	Q9H2X6	HIPK2	S395	S389F	389	Missense	distal	-6	no	106.730	106.531	EPSD	TCGA;ICGC;COSMIC	98.777	Down-regulation
CMGC_DYRK_HIPK_HIPK2_ST	Q9H3D4	TP63	Q9H2X6	HIPK2	S395	D397G	397	Missense	proximal	2	no	106.730	107.122	EPSD	TCGA;COSMIC	98.777	Up-regulation
CMGC_DYRK_HIPK_HIPK2_ST	Q9H3D4	TP63	Q9H2X6	HIPK2	S395	R393Q	393	Missense	proximal	-2	no	106.730	107.028	EPSD	TCGA;COSMIC	98.777	Up-regulation
CMGC_DYRK_HIPK_HIPK2_ST	Q9H3D4	TP63	Q9H2X6	HIPK2	S395	K391N	391	Missense	distal	-4	no	106.730	106.588	EPSD	TCGA;COSMIC	98.777	Down-regulation
CMGC_DYRK_HIPK_HIPK2_ST	Q9H3D4	TP63	Q9H2X6	HIPK2	S455	S458L	458	Missense	distal	3	no	108.088	107.552	EPSD	TCGA;COSMIC	98.777	Down-regulation
CMGC_DYRK_HIPK_HIPK2_ST	Q9H3D4	TP63	Q9H2X6	HIPK2	S455	P456L	456	Missense	proximal	1	no	108.088	-12.197	EPSD	TCGA;COSMIC	98.777	Loss
CMGC_DYRK_HIPK_HIPK2_ST	Q9H3D4	TP63	Q9H2X6	HIPK2	S463	P464L	464	Missense	proximal	1	no	109.982	-10.303	EPSD	TCGA;COSMIC	98.777	Loss
CMGC_DYRK_HIPK_HIPK2_ST	Q9H3D4	TP63	Q9H2X6	HIPK2	S463	M469I	469	Missense	distal	6	no	109.982	110.191	EPSD	TCGA;COSMIC	98.777	Up-regulation
CMGC_DYRK_HIPK_HIPK2_ST	Q9H3D4	TP63	Q9H2X6	HIPK2	S463	N467S	467	Missense	distal	4	no	109.982	112.669	EPSD	TCGA;COSMIC	98.777	Up-regulation
CMGC_DYRK_HIPK_HIPK2_ST	Q9H3D4	TP63	Q9H2X6	HIPK2	S463	S458L	458	Missense	distal	-5	no	109.982	106.821	EPSD	TCGA;COSMIC	98.777	Down-regulation
CMGC_DYRK_HIPK_HIPK2_ST	Q9H3D4	TP63	Q9H2X6	HIPK2	S463	P456L	456	Missense	distal	-7	no	109.982	108.896	EPSD	TCGA;COSMIC	98.777	Down-regulation
CMGC_DYRK_HIPK_HIPK2_ST	Q9H3D4	TP63	Q9H2X6	HIPK2	T491	P492A	492	Missense	proximal	1	no	114.097	-14.427	PhosphoSitePlus	TCGA;COSMIC	98.777	Loss
CMGC_DYRK_HIPK_HIPK2_ST	Q9H3D4	TP63	Q9H2X6	HIPK2	T491	P492S	492	Missense	proximal	1	no	114.097	96.817	PhosphoSitePlus	TCGA;COSMIC	98.777	Loss
CMGC_DYRK_HIPK_HIPK2_ST	Q9H3D4	TP63	Q9H2X6	HIPK2	T491	R487C	487	Missense	distal	-4	no	114.097	113.719	PhosphoSitePlus	TCGA;COSMIC	98.777	Down-regulation
CMGC_DYRK_HIPK_HIPK2_ST	Q9H3D4	TP63	Q9H2X6	HIPK2	T491	P496S	496	Missense	distal	5	no	114.097	114.098	PhosphoSitePlus	TCGA;COSMIC	98.777	Up-regulation
CMGC_DYRK_HIPK_HIPK2_ST	Q9H3D4	TP63	Q9H2X6	HIPK2	T491	R487S	487	Missense	distal	-4	no	114.097	114.223	PhosphoSitePlus	TCGA	98.777	Up-regulation
CMGC_DYRK_HIPK_HIPK2_ST	Q9H3D4	TP63	Q9H2X6	HIPK2	T491	A489T	489	Missense	proximal	-2	no	114.097	113.879	PhosphoSitePlus	TCGA;COSMIC	98.777	Down-regulation
CMGC_DYRK_HIPK_HIPK2_ST	Q9H3D4	TP63	Q9H2X6	HIPK2	T491	R487H	487	Missense	distal	-4	no	114.097	113.883	PhosphoSitePlus	TCGA;COSMIC	98.777	Down-regulation
CMGC_DYRK_HIPK_HIPK2_ST	Q9H3D4	TP63	Q9H2X6	HIPK2	S612	H615Y	615	Missense	distal	3	no	99.370	99.548	EPSD	TCGA;COSMIC	98.777	Up-regulation
CMGC_DYRK_HIPK_HIPK2_ST	Q9H3D4	TP63	Q9H2X6	HIPK2	S612	F610L	610	Missense	proximal	-2	no	99.370	99.708	EPSD	TCGA;COSMIC	98.777	Up-regulation
CMGC_DYRK_HIPK_HIPK2_ST	Q9H3D4	TP63	Q9H2X6	HIPK2	T619	H615Y	615	Missense	distal	-4	no	110.853	111.000	EPSD	TCGA;COSMIC	98.777	Up-regulation
Atypical_PIKK_FRAP_MTOR_ST	Q8N122	RPTOR	P42345	MTOR	S704	R709Q	709	Missense	distal	5	no	10.835	10.028	EPSD	TCGA;COSMIC	6.822	Down-regulation
Atypical_PIKK_FRAP_MTOR_ST	Q8N122	RPTOR	P42345	MTOR	T706	C713F	713	Missense	distal	7	no	8.436	7.794	EPSD	TCGA	6.822	Down-regulation
Atypical_PIKK_FRAP_MTOR_ST	Q8N122	RPTOR	P42345	MTOR	T706	R709Q	709	Missense	distal	3	no	8.436	7.170	EPSD	TCGA;COSMIC	6.822	Down-regulation
Atypical_PIKK_FRAP_MTOR_ST	Q8N122	RPTOR	P42345	MTOR	S771	E775K	775	Missense	distal	4	no	8.513	8.474	EPSD	TCGA;COSMIC	6.822	Down-regulation
Atypical_PIKK_FRAP_MTOR_ST	Q8N122	RPTOR	P42345	MTOR	S863	T857M	857	Missense	distal	-6	no	10.953	11.023	EPSD;PhosphoSitePlus	TCGA;COSMIC	6.822	Up-regulation
Atypical_PIKK_FRAP_MTOR_ST	Q8N122	RPTOR	P42345	MTOR	S877	S877F	877	Missense	central	0	yes	10.049	0.000	EPSD	TCGA;COSMIC	6.822	Loss
Atypical_PIKK_FRAP_MTOR_ST	Q8N122	RPTOR	P42345	MTOR	S877	P879L	879	Missense	proximal	2	no	10.049	9.360	EPSD	TCGA;COSMIC	6.822	Down-regulation
Atypical_PIKK_FRAP_MTOR_ST	Q8N122	RPTOR	P42345	MTOR	S882	S877F	877	Missense	distal	-5	no	7.315	7.322	EPSD	TCGA;COSMIC	6.822	Up-regulation
Atypical_PIKK_FRAP_MTOR_ST	Q8N122	RPTOR	P42345	MTOR	S882	P879L	879	Missense	distal	-3	no	7.315	8.163	EPSD	TCGA;COSMIC	6.822	Up-regulation
Atypical_PIKK_FRAP_MTOR_ST	Q13541	EIF4EBP1	P42345	MTOR	T70	L75M	75	Missense	distal	5	no	9.629	8.009	EPSD;PhosphoSitePlus	TCGA;ICGC	6.822	Down-regulation
Atypical_PIKK_FRAP_MTOR_ST	Q13541	EIF4EBP1	P42345	MTOR	S83	S86N	86	Missense	distal	3	no	14.242	13.699	EPSD	TCGA;ICGC;COSMIC	6.822	Down-regulation
Atypical_PIKK_FRAP_MTOR_ST	Q13541	EIF4EBP1	P42345	MTOR	S101	A107V	107	Missense	distal	6	no	15.851	16.543	EPSD	TCGA;ICGC;COSMIC;GDSC;CCLE	6.822	Up-regulation
Atypical_PIKK_FRAP_MTOR_ST	P00441	SOD1	P42345	MTOR	S103	I105M	105	Missense	proximal	2	no	10.071	8.684	EPSD	TCGA;COSMIC	6.822	Down-regulation
Atypical_PIKK_FRAP_MTOR_ST	P00441	SOD1	P42345	MTOR	S103	D97N	97	Missense	distal	-6	no	10.071	9.280	EPSD	TCGA	6.822	Down-regulation
Atypical_PIKK_FRAP_MTOR_ST	P00441	SOD1	P42345	MTOR	S103	S103F	103	Missense	central	0	yes	10.071	0.000	EPSD	TCGA	6.822	Loss
Atypical_PIKK_FRAP_MTOR_ST	P00441	SOD1	P42345	MTOR	S106	I105M	105	Missense	proximal	-1	no	9.137	9.270	EPSD	TCGA;COSMIC	6.822	Up-regulation
Atypical_PIKK_FRAP_MTOR_ST	P00441	SOD1	P42345	MTOR	S106	H111N	111	Missense	distal	5	no	9.137	9.321	EPSD	TCGA;COSMIC	6.822	Up-regulation
Atypical_PIKK_FRAP_MTOR_ST	P00441	SOD1	P42345	MTOR	S106	S103F	103	Missense	distal	-3	no	9.137	9.208	EPSD	TCGA	6.822	Up-regulation
Atypical_PIKK_FRAP_MTOR_ST	P00441	SOD1	P42345	MTOR	S106	H111Y	111	Missense	distal	5	no	9.137	8.704	EPSD	TCGA;COSMIC	6.822	Down-regulation
Atypical_PIKK_FRAP_MTOR_ST	O75179	ANKRD17	P42345	MTOR	S47	G41S	41	Missense	distal	-6	no	10.021	9.899	EPSD	TCGA;ICGC;COSMIC	6.822	Down-regulation
Atypical_PIKK_FRAP_MTOR_ST	O75179	ANKRD17	P42345	MTOR	S113	G106D	106	Missense	distal	-7	no	6.776	7.583	EPSD	TCGA;ICGC;COSMIC	6.822	Gain
Atypical_PIKK_FRAP_MTOR_ST	O75179	ANKRD17	P42345	MTOR	T735	L734F	734	Missense	proximal	-1	no	9.022	9.040	EPSD	TCGA;ICGC;COSMIC	6.822	Up-regulation
Atypical_PIKK_FRAP_MTOR_ST	O75179	ANKRD17	P42345	MTOR	T735	Q733E	733	Missense	proximal	-2	no	9.022	8.900	EPSD	TCGA;COSMIC	6.822	Down-regulation
Atypical_PIKK_FRAP_MTOR_ST	O75179	ANKRD17	P42345	MTOR	T735	D740N	740	Missense	distal	5	no	9.022	10.469	EPSD	TCGA;COSMIC;GDSC;CCLE	6.822	Up-regulation
Atypical_PIKK_FRAP_MTOR_ST	O75179	ANKRD17	P42345	MTOR	S1607	S1609R	1609	Missense	proximal	2	no	7.673	5.961	EPSD	TCGA;ICGC;COSMIC	6.822	Loss
Atypical_PIKK_FRAP_MTOR_ST	O75179	ANKRD17	P42345	MTOR	S1607	E1610K	1610	Missense	distal	3	no	7.673	6.043	EPSD	TCGA;ICGC	6.822	Loss
Atypical_PIKK_FRAP_MTOR_ST	O75179	ANKRD17	P42345	MTOR	S1672	K1674Q	1674	Missense	proximal	2	no	7.344	5.686	EPSD	TCGA;ICGC;COSMIC	6.822	Loss
Atypical_PIKK_FRAP_MTOR_ST	O75179	ANKRD17	P42345	MTOR	S1672	E1677D	1677	Missense	distal	5	no	7.344	7.762	EPSD	TCGA;COSMIC	6.822	Up-regulation
Atypical_PIKK_FRAP_MTOR_ST	O75179	ANKRD17	P42345	MTOR	S1709	P1710A	1710	Missense	proximal	1	no	12.485	3.602	EPSD	TCGA;COSMIC	6.822	Loss
Atypical_PIKK_FRAP_MTOR_ST	O75179	ANKRD17	P42345	MTOR	S1709	R1712C	1712	Missense	distal	3	no	12.485	9.997	EPSD	TCGA;COSMIC	6.822	Down-regulation
Atypical_PIKK_FRAP_MTOR_ST	O75179	ANKRD17	P42345	MTOR	S1731	T1735A	1735	Missense	distal	4	no	6.898	6.356	EPSD	TCGA;COSMIC	6.822	Loss
Atypical_PIKK_FRAP_MTOR_ST	O75179	ANKRD17	P42345	MTOR	S1734	T1735A	1735	Missense	proximal	1	no	8.990	6.379	EPSD	TCGA;COSMIC	6.822	Loss
Atypical_PIKK_FRAP_MTOR_ST	O75179	ANKRD17	P42345	MTOR	S2059	V2055A	2055	Missense	distal	-4	no	12.200	11.920	EPSD	TCGA	6.822	Down-regulation
Atypical_PIKK_FRAP_MTOR_ST	O75179	ANKRD17	P42345	MTOR	S2081	E2076K	2076	Missense	distal	-5	no	8.988	9.280	EPSD	TCGA;COSMIC;GDSC;CCLE	6.822	Up-regulation
Atypical_PIKK_FRAP_MTOR_ST	O75179	ANKRD17	P42345	MTOR	T2279	S2285P	2285	Missense	distal	6	no	12.302	12.273	EPSD	TCGA;COSMIC	6.822	Down-regulation
Atypical_PIKK_FRAP_MTOR_ST	O75179	ANKRD17	P42345	MTOR	T2279	S2285L	2285	Missense	distal	6	no	12.302	11.113	EPSD	TCGA;COSMIC	6.822	Down-regulation
Atypical_PIKK_FRAP_MTOR_ST	O75179	ANKRD17	P42345	MTOR	S2289	S2285P	2285	Missense	distal	-4	no	7.521	7.392	EPSD	TCGA;COSMIC	6.822	Down-regulation
Atypical_PIKK_FRAP_MTOR_ST	O75179	ANKRD17	P42345	MTOR	S2289	P2292L	2292	Missense	distal	3	no	7.521	5.267	EPSD	TCGA;COSMIC	6.822	Loss
Atypical_PIKK_FRAP_MTOR_ST	O75179	ANKRD17	P42345	MTOR	S2289	S2285L	2285	Missense	distal	-4	no	7.521	7.206	EPSD	TCGA;COSMIC	6.822	Down-regulation
Atypical_PIKK_FRAP_MTOR_ST	O75179	ANKRD17	P42345	MTOR	S2289	P2296H	2296	Missense	distal	7	no	7.521	8.136	EPSD	TCGA	6.822	Up-regulation
Atypical_PIKK_FRAP_MTOR_ST	O75179	ANKRD17	P42345	MTOR	S2373	S2373P	2373	Missense	central	0	yes	11.026	0.000	EPSD	TCGA;COSMIC	6.822	Loss
Atypical_PIKK_FRAP_MTOR_ST	O75179	ANKRD17	P42345	MTOR	S2401	P2408L	2408	Missense	distal	7	no	11.495	12.451	EPSD	TCGA;COSMIC	6.822	Up-regulation
Atypical_PIKK_FRAP_MTOR_ST	O75179	ANKRD17	P42345	MTOR	S2448	S2448I	2448	Missense	central	0	yes	10.470	0.000	EPSD	TCGA	6.822	Loss
Atypical_PIKK_FRAP_MTOR_ST	O75179	ANKRD17	P42345	MTOR	T2509	Q2516R	2516	Missense	distal	7	no	9.021	9.421	EPSD	TCGA;COSMIC	6.822	Up-regulation
Atypical_PIKK_FRAP_MTOR_ST	O75179	ANKRD17	P42345	MTOR	T2509	R2502Q	2502	Missense	distal	-7	no	9.021	8.944	EPSD	TCGA;COSMIC	6.822	Down-regulation
Atypical_PIKK_FRAP_MTOR_ST	Q9HB90	RRAGC	P42345	MTOR	S86	N88K	88	Missense	proximal	2	no	9.375	10.710	EPSD	TCGA;ICGC;COSMIC	6.822	Up-regulation
Atypical_PIKK_FRAP_MTOR_ST	Q9HB90	RRAGC	P42345	MTOR	S382	S385C	385	Missense	distal	3	no	7.160	4.393	EPSD	TCGA;ICGC;COSMIC	6.822	Loss
Atypical_PIKK_FRAP_MTOR_ST	Q9HB90	RRAGC	P42345	MTOR	T394	T390K	390	Missense	distal	-4	no	8.997	9.080	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	6.822	Up-regulation
Atypical_PIKK_FRAP_MTOR_ST	Q9HB90	RRAGC	P42345	MTOR	T394	R396Q	396	Missense	proximal	2	no	8.997	8.985	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC;CCLE	6.822	Down-regulation
Atypical_PIKK_FRAP_MTOR_ST	O00418	EEF2K	P42345	MTOR	S18	H23Y	23	Missense	distal	5	no	13.463	13.030	EPSD	TCGA;ICGC;COSMIC	6.822	Down-regulation
Atypical_PIKK_FRAP_MTOR_ST	O00418	EEF2K	P42345	MTOR	S31	S31N	31	Missense	central	0	yes	7.324	0.000	EPSD	TCGA;ICGC;COSMIC	6.822	Loss
Atypical_PIKK_FRAP_MTOR_ST	O00418	EEF2K	P42345	MTOR	S31	D33N	33	Missense	proximal	2	no	7.324	6.065	EPSD	TCGA;ICGC;COSMIC	6.822	Loss
Atypical_PIKK_FRAP_MTOR_ST	O00418	EEF2K	P42345	MTOR	S31	E35D	35	Missense	distal	4	no	7.324	7.485	EPSD	TCGA;ICGC	6.822	Up-regulation
Atypical_PIKK_FRAP_MTOR_ST	O00418	EEF2K	P42345	MTOR	S71	E67K	67	Missense	distal	-4	no	8.697	8.399	EPSD	TCGA;ICGC;COSMIC	6.822	Down-regulation
Atypical_PIKK_FRAP_MTOR_ST	O00418	EEF2K	P42345	MTOR	S71	R68W	68	Missense	distal	-3	no	8.697	8.482	EPSD	TCGA	6.822	Down-regulation
Atypical_PIKK_FRAP_MTOR_ST	O00418	EEF2K	P42345	MTOR	S71	S74C	74	Missense	distal	3	no	8.697	5.930	EPSD	TCGA;ICGC;COSMIC	6.822	Loss
Atypical_PIKK_FRAP_MTOR_ST	O00418	EEF2K	P42345	MTOR	S72	E67K	67	Missense	distal	-5	no	9.703	9.995	PhosphoSitePlus;EPSD	TCGA;ICGC;COSMIC	6.822	Up-regulation
Atypical_PIKK_FRAP_MTOR_ST	O00418	EEF2K	P42345	MTOR	S72	R68W	68	Missense	distal	-4	no	9.703	9.813	PhosphoSitePlus;EPSD	TCGA	6.822	Up-regulation
Atypical_PIKK_FRAP_MTOR_ST	O00418	EEF2K	P42345	MTOR	S72	S74C	74	Missense	proximal	2	no	9.703	8.157	PhosphoSitePlus;EPSD	TCGA;ICGC;COSMIC	6.822	Down-regulation
Atypical_PIKK_FRAP_MTOR_ST	O00418	EEF2K	P42345	MTOR	S74	E67K	67	Missense	distal	-7	no	12.409	12.200	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	6.822	Down-regulation
Atypical_PIKK_FRAP_MTOR_ST	O00418	EEF2K	P42345	MTOR	S74	H80Y	80	Missense	distal	6	no	12.409	12.483	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	6.822	Up-regulation
Atypical_PIKK_FRAP_MTOR_ST	O00418	EEF2K	P42345	MTOR	S74	R68W	68	Missense	distal	-6	no	12.409	12.782	EPSD;PhosphoSitePlus	TCGA	6.822	Up-regulation
Atypical_PIKK_FRAP_MTOR_ST	O00418	EEF2K	P42345	MTOR	S74	S74C	74	Missense	central	0	yes	12.409	0.000	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	6.822	Loss
Atypical_PIKK_FRAP_MTOR_ST	O00418	EEF2K	P42345	MTOR	S359	S366F	366	Missense	distal	7	no	6.318	6.899	EPSD	TCGA;ICGC;COSMIC	6.822	Gain
Atypical_PIKK_FRAP_MTOR_ST	O00418	EEF2K	P42345	MTOR	S359	S366C	366	Missense	distal	7	no	6.318	7.541	EPSD	TCGA;ICGC;COSMIC	6.822	Gain
Atypical_PIKK_FRAP_MTOR_ST	O00418	EEF2K	P42345	MTOR	T389	D387N	387	Missense	proximal	-2	no	7.817	7.550	EPSD	TCGA;ICGC	6.822	Down-regulation
Atypical_PIKK_FRAP_MTOR_ST	O00418	EEF2K	P42345	MTOR	T389	S396F	396	Missense	distal	7	no	7.817	8.397	EPSD	TCGA;ICGC;COSMIC	6.822	Up-regulation
Atypical_PIKK_FRAP_MTOR_ST	O00418	EEF2K	P42345	MTOR	T389	S392F	392	Missense	distal	3	no	7.817	8.221	EPSD	TCGA;ICGC;COSMIC	6.822	Up-regulation
Atypical_PIKK_FRAP_MTOR_ST	O00418	EEF2K	P42345	MTOR	T389	M385T	385	Missense	distal	-4	no	7.817	8.041	EPSD	TCGA;ICGC	6.822	Up-regulation
Atypical_PIKK_FRAP_MTOR_ST	O00418	EEF2K	P42345	MTOR	T389	D391N	391	Missense	proximal	2	no	7.817	6.558	EPSD	TCGA;ICGC	6.822	Loss
Atypical_PIKK_FRAP_MTOR_ST	O00418	EEF2K	P42345	MTOR	S396	A400V	400	Missense	distal	4	no	7.533	7.695	EPSD	TCGA;ICGC;COSMIC	6.822	Up-regulation
Atypical_PIKK_FRAP_MTOR_ST	O00418	EEF2K	P42345	MTOR	S396	S396F	396	Missense	central	0	yes	7.533	0.000	EPSD	TCGA;ICGC;COSMIC	6.822	Loss
Atypical_PIKK_FRAP_MTOR_ST	O00418	EEF2K	P42345	MTOR	S396	S392F	392	Missense	distal	-4	no	7.533	7.558	EPSD	TCGA;ICGC;COSMIC	6.822	Up-regulation
Atypical_PIKK_FRAP_MTOR_ST	O00418	EEF2K	P42345	MTOR	S396	D391N	391	Missense	distal	-5	no	7.533	7.489	EPSD	TCGA;ICGC	6.822	Down-regulation
Atypical_PIKK_FRAP_MTOR_ST	O00418	EEF2K	P42345	MTOR	S627	D621N	621	Missense	distal	-6	no	10.759	9.967	EPSD	TCGA;ICGC;COSMIC	6.822	Down-regulation
Atypical_PIKK_FRAP_MTOR_ST	O00418	EEF2K	P42345	MTOR	S627	D633G	633	Missense	distal	6	no	10.759	10.972	EPSD	TCGA;ICGC;COSMIC	6.822	Up-regulation
Atypical_PIKK_FRAP_MTOR_ST	Q9UQ35	SRRM2	P42345	MTOR	T111	G107A	107	Missense	distal	-4	no	7.502	7.106	EPSD	TCGA;ICGC;COSMIC	6.822	Down-regulation
Atypical_PIKK_FRAP_MTOR_ST	Q9UQ35	SRRM2	P42345	MTOR	T111	Q114H	114	Missense	distal	3	no	7.502	8.938	EPSD	TCGA;ICGC;COSMIC;GDSC;CCLE	6.822	Up-regulation
Atypical_PIKK_FRAP_MTOR_ST	Q9UQ35	SRRM2	P42345	MTOR	S172	S177C	177	Missense	distal	5	no	8.383	9.160	EPSD	TCGA;ICGC;COSMIC	6.822	Up-regulation
Atypical_PIKK_FRAP_MTOR_ST	Q9UQ35	SRRM2	P42345	MTOR	S172	R175W	175	Missense	distal	3	no	8.383	6.624	EPSD	TCGA;ICGC;COSMIC	6.822	Loss
Atypical_PIKK_FRAP_MTOR_ST	Q9UQ35	SRRM2	P42345	MTOR	S172	S179R	179	Missense	distal	7	no	8.383	9.176	EPSD	TCGA;ICGC;COSMIC	6.822	Up-regulation
Atypical_PIKK_FRAP_MTOR_ST	Q9UQ35	SRRM2	P42345	MTOR	S182	S177C	177	Missense	distal	-5	no	11.510	11.776	EPSD	TCGA;ICGC;COSMIC	6.822	Up-regulation
Atypical_PIKK_FRAP_MTOR_ST	Q9UQ35	SRRM2	P42345	MTOR	S182	R175W	175	Missense	distal	-7	no	11.510	11.970	EPSD	TCGA;ICGC;COSMIC	6.822	Up-regulation
Atypical_PIKK_FRAP_MTOR_ST	Q9UQ35	SRRM2	P42345	MTOR	S182	S179R	179	Missense	distal	-3	no	11.510	11.856	EPSD	TCGA;ICGC;COSMIC	6.822	Up-regulation
Atypical_PIKK_FRAP_MTOR_ST	Q9UQ35	SRRM2	P42345	MTOR	S182	R181H	181	Missense	proximal	-1	no	11.510	11.551	EPSD	TCGA;ICGC;COSMIC	6.822	Up-regulation
Atypical_PIKK_FRAP_MTOR_ST	Q9UQ35	SRRM2	P42345	MTOR	T184	S177C	177	Missense	distal	-7	no	11.408	9.555	EPSD	TCGA;ICGC;COSMIC	6.822	Down-regulation
Atypical_PIKK_FRAP_MTOR_ST	Q9UQ35	SRRM2	P42345	MTOR	T184	S179R	179	Missense	distal	-5	no	11.408	11.550	EPSD	TCGA;ICGC;COSMIC	6.822	Up-regulation
Atypical_PIKK_FRAP_MTOR_ST	Q9UQ35	SRRM2	P42345	MTOR	T184	R181H	181	Missense	distal	-3	no	11.408	10.661	EPSD	TCGA;ICGC;COSMIC	6.822	Down-regulation
Atypical_PIKK_FRAP_MTOR_ST	Q9UQ35	SRRM2	P42345	MTOR	S204	E201K	201	Missense	distal	-3	no	8.276	8.282	EPSD	TCGA;ICGC;COSMIC	6.822	Up-regulation
Atypical_PIKK_FRAP_MTOR_ST	Q9UQ35	SRRM2	P42345	MTOR	S204	P205L	205	Missense	proximal	1	no	8.276	2.307	EPSD	TCGA;ICGC;COSMIC	6.822	Loss
Atypical_PIKK_FRAP_MTOR_ST	Q9UQ35	SRRM2	P42345	MTOR	S204	R199M	199	Missense	distal	-5	no	8.276	8.129	EPSD	TCGA;ICGC;COSMIC	6.822	Down-regulation
Atypical_PIKK_FRAP_MTOR_ST	Q9UQ35	SRRM2	P42345	MTOR	S204	R198C	198	Missense	distal	-6	no	8.276	8.403	EPSD	TCGA;ICGC;COSMIC	6.822	Up-regulation
Atypical_PIKK_FRAP_MTOR_ST	Q9UQ35	SRRM2	P42345	MTOR	S231	P232S	232	Missense	proximal	1	no	9.139	0.615	EPSD	TCGA;ICGC	6.822	Loss
Atypical_PIKK_FRAP_MTOR_ST	Q9UQ35	SRRM2	P42345	MTOR	S231	S231F	231	Missense	central	0	yes	9.139	0.000	EPSD	TCGA;ICGC;COSMIC	6.822	Loss
Atypical_PIKK_FRAP_MTOR_ST	Q9UQ35	SRRM2	P42345	MTOR	T252	R245Q	245	Missense	distal	-7	no	10.245	10.168	EPSD	TCGA;ICGC;COSMIC	6.822	Down-regulation
Atypical_PIKK_FRAP_MTOR_ST	Q9UQ35	SRRM2	P42345	MTOR	T252	P255L	255	Missense	distal	3	no	10.245	7.991	EPSD	TCGA;ICGC;COSMIC	6.822	Down-regulation
Atypical_PIKK_FRAP_MTOR_ST	Q9UQ35	SRRM2	P42345	MTOR	T252	R249Q	249	Missense	distal	-3	no	10.245	9.637	EPSD	TCGA;ICGC;COSMIC	6.822	Down-regulation
Atypical_PIKK_FRAP_MTOR_ST	Q9UQ35	SRRM2	P42345	MTOR	S271	A269S	269	Missense	proximal	-2	no	7.939	7.378	EPSD	TCGA;ICGC;COSMIC	6.822	Down-regulation
Atypical_PIKK_FRAP_MTOR_ST	Q9UQ35	SRRM2	P42345	MTOR	S297	R303H	303	Missense	distal	6	no	9.264	9.581	EPSD	TCGA;ICGC;COSMIC	6.822	Up-regulation
Atypical_PIKK_FRAP_MTOR_ST	Q9UQ35	SRRM2	P42345	MTOR	S297	G304R	304	Missense	distal	7	no	9.264	9.672	EPSD	TCGA;ICGC;COSMIC	6.822	Up-regulation
Atypical_PIKK_FRAP_MTOR_ST	Q9UQ35	SRRM2	P42345	MTOR	S323	R320Q	320	Missense	distal	-3	no	15.265	14.656	EPSD	TCGA;ICGC	6.822	Down-regulation
Atypical_PIKK_FRAP_MTOR_ST	Q9UQ35	SRRM2	P42345	MTOR	S351	S358N	358	Missense	distal	7	no	12.023	12.622	EPSD	TCGA;ICGC;COSMIC	6.822	Up-regulation
Atypical_PIKK_FRAP_MTOR_ST	Q9UQ35	SRRM2	P42345	MTOR	S353	S358N	358	Missense	distal	5	no	10.140	11.621	EPSD	TCGA;ICGC;COSMIC	6.822	Up-regulation
Atypical_PIKK_FRAP_MTOR_ST	Q9UQ35	SRRM2	P42345	MTOR	S398	E396K	396	Missense	proximal	-2	no	8.860	8.898	EPSD	TCGA;ICGC;COSMIC	6.822	Up-regulation
Atypical_PIKK_FRAP_MTOR_ST	Q9UQ35	SRRM2	P42345	MTOR	S456	R451Q	451	Missense	distal	-5	no	11.934	11.849	EPSD	TCGA;ICGC;COSMIC	6.822	Down-regulation
Atypical_PIKK_FRAP_MTOR_ST	Q9UQ35	SRRM2	P42345	MTOR	S456	R462H	462	Missense	distal	6	no	11.934	12.250	EPSD	TCGA;ICGC;COSMIC	6.822	Up-regulation
Atypical_PIKK_FRAP_MTOR_ST	Q9UQ35	SRRM2	P42345	MTOR	T476	G482V	482	Missense	distal	6	no	8.522	8.633	EPSD	TCGA;ICGC;COSMIC	6.822	Up-regulation
Atypical_PIKK_FRAP_MTOR_ST	Q9UQ35	SRRM2	P42345	MTOR	T476	S472L	472	Missense	distal	-4	no	8.522	8.206	EPSD	TCGA;ICGC;COSMIC	6.822	Down-regulation
Atypical_PIKK_FRAP_MTOR_ST	Q9UQ35	SRRM2	P42345	MTOR	T476	P477S	477	Missense	proximal	1	no	8.522	-0.002	EPSD	TCGA;ICGC;COSMIC	6.822	Loss
Atypical_PIKK_FRAP_MTOR_ST	Q9UQ35	SRRM2	P42345	MTOR	T476	T476A	476	Missense	central	0	yes	8.522	0.000	EPSD	TCGA;ICGC;COSMIC	6.822	Loss
Atypical_PIKK_FRAP_MTOR_ST	Q9UQ35	SRRM2	P42345	MTOR	T476	R483K	483	Missense	distal	7	no	8.522	7.376	EPSD	TCGA;ICGC;COSMIC	6.822	Down-regulation
Atypical_PIKK_FRAP_MTOR_ST	Q9UQ35	SRRM2	P42345	MTOR	S486	G482V	482	Missense	distal	-4	no	9.657	9.541	EPSD	TCGA;ICGC;COSMIC	6.822	Down-regulation
Atypical_PIKK_FRAP_MTOR_ST	Q9UQ35	SRRM2	P42345	MTOR	S486	S486G	486	Missense	central	0	yes	9.657	0.000	EPSD	TCGA;ICGC;COSMIC	6.822	Loss
Atypical_PIKK_FRAP_MTOR_ST	Q9UQ35	SRRM2	P42345	MTOR	S486	R483K	483	Missense	distal	-3	no	9.657	8.943	EPSD	TCGA;ICGC;COSMIC	6.822	Down-regulation
Atypical_PIKK_FRAP_MTOR_ST	Q9UQ35	SRRM2	P42345	MTOR	S534	S536F	536	Missense	proximal	2	no	7.694	5.960	EPSD	TCGA;ICGC;COSMIC	6.822	Loss
Atypical_PIKK_FRAP_MTOR_ST	Q9UQ35	SRRM2	P42345	MTOR	S534	Q529H	529	Missense	distal	-5	no	7.694	7.784	EPSD	TCGA;ICGC	6.822	Up-regulation
Atypical_PIKK_FRAP_MTOR_ST	Q9UQ35	SRRM2	P42345	MTOR	S534	R531H	531	Missense	distal	-3	no	7.694	6.947	EPSD	TCGA;ICGC;COSMIC	6.822	Down-regulation
Atypical_PIKK_FRAP_MTOR_ST	Q9UQ35	SRRM2	P42345	MTOR	S543	R546T	546	Missense	distal	3	no	6.935	6.807	EPSD	TCGA;ICGC;COSMIC	6.822	Loss
Atypical_PIKK_FRAP_MTOR_ST	Q9UQ35	SRRM2	P42345	MTOR	S543	S536F	536	Missense	distal	-7	no	6.935	6.709	EPSD	TCGA;ICGC;COSMIC	6.822	Loss
Atypical_PIKK_FRAP_MTOR_ST	Q9UQ35	SRRM2	P42345	MTOR	S562	H563Y	563	Missense	proximal	1	no	-14.468	7.893	EPSD	TCGA;ICGC;COSMIC	6.822	Gain
Atypical_PIKK_FRAP_MTOR_ST	Q9UQ35	SRRM2	P42345	MTOR	S566	S564C	564	Missense	proximal	-2	no	11.868	12.018	EPSD	TCGA;ICGC;COSMIC	6.822	Up-regulation
Atypical_PIKK_FRAP_MTOR_ST	Q9UQ35	SRRM2	P42345	MTOR	S566	H563Y	563	Missense	distal	-3	no	11.868	12.509	EPSD	TCGA;ICGC;COSMIC	6.822	Up-regulation
Atypical_PIKK_FRAP_MTOR_ST	Q9UQ35	SRRM2	P42345	MTOR	T577	R580C	580	Missense	distal	3	no	7.518	5.030	EPSD	TCGA;ICGC;CCLE	6.822	Loss
Atypical_PIKK_FRAP_MTOR_ST	Q9UQ35	SRRM2	P42345	MTOR	T588	R591K	591	Missense	distal	3	no	8.675	7.577	EPSD	TCGA;ICGC;COSMIC	6.822	Down-regulation
Atypical_PIKK_FRAP_MTOR_ST	Q9UQ35	SRRM2	P42345	MTOR	T588	S594L	594	Missense	distal	6	no	8.675	7.486	EPSD	TCGA;ICGC;COSMIC	6.822	Down-regulation
Atypical_PIKK_FRAP_MTOR_ST	Q9UQ35	SRRM2	P42345	MTOR	T588	R592Q	592	Missense	distal	4	no	8.675	8.807	EPSD	TCGA;ICGC;COSMIC	6.822	Up-regulation
Atypical_PIKK_FRAP_MTOR_ST	Q9UQ35	SRRM2	P42345	MTOR	T588	T588I	588	Missense	central	0	yes	8.675	0.000	EPSD	TCGA;ICGC;COSMIC	6.822	Loss
Atypical_PIKK_FRAP_MTOR_ST	Q9UQ35	SRRM2	P42345	MTOR	T588	R592W	592	Missense	distal	4	no	8.675	8.837	EPSD	TCGA;ICGC;COSMIC	6.822	Up-regulation
Atypical_PIKK_FRAP_MTOR_ST	Q9UQ35	SRRM2	P42345	MTOR	T588	A590D	590	Missense	proximal	2	no	8.675	9.296	EPSD	TCGA;ICGC	6.822	Up-regulation
Atypical_PIKK_FRAP_MTOR_ST	Q9UQ35	SRRM2	P42345	MTOR	T598	R602C	602	Missense	distal	4	no	11.114	10.901	EPSD	TCGA;ICGC;COSMIC	6.822	Down-regulation
Atypical_PIKK_FRAP_MTOR_ST	Q9UQ35	SRRM2	P42345	MTOR	T598	R601S	601	Missense	distal	3	no	11.114	11.394	EPSD	TCGA;ICGC;COSMIC	6.822	Up-regulation
Atypical_PIKK_FRAP_MTOR_ST	Q9UQ35	SRRM2	P42345	MTOR	T598	R591K	591	Missense	distal	-7	no	11.114	11.259	EPSD	TCGA;ICGC;COSMIC	6.822	Up-regulation
Atypical_PIKK_FRAP_MTOR_ST	Q9UQ35	SRRM2	P42345	MTOR	T598	R605W	605	Missense	distal	7	no	11.114	10.728	EPSD	TCGA;ICGC;COSMIC;CCLE	6.822	Down-regulation
Atypical_PIKK_FRAP_MTOR_ST	Q9UQ35	SRRM2	P42345	MTOR	T598	S594L	594	Missense	distal	-4	no	11.114	10.799	EPSD	TCGA;ICGC;COSMIC	6.822	Down-regulation
Atypical_PIKK_FRAP_MTOR_ST	Q9UQ35	SRRM2	P42345	MTOR	T598	R592Q	592	Missense	distal	-6	no	11.114	10.850	EPSD	TCGA;ICGC;COSMIC	6.822	Down-regulation
Atypical_PIKK_FRAP_MTOR_ST	Q9UQ35	SRRM2	P42345	MTOR	T598	R592W	592	Missense	distal	-6	no	11.114	11.487	EPSD	TCGA;ICGC;COSMIC	6.822	Up-regulation
Atypical_PIKK_FRAP_MTOR_ST	Q9UQ35	SRRM2	P42345	MTOR	T598	R603K	603	Missense	distal	5	no	11.114	9.793	EPSD	TCGA;ICGC	6.822	Down-regulation
Atypical_PIKK_FRAP_MTOR_ST	Q9UQ35	SRRM2	P42345	MTOR	T598	R597G	597	Missense	proximal	-1	no	11.114	11.269	EPSD	TCGA	6.822	Up-regulation
Atypical_PIKK_FRAP_MTOR_ST	Q9UQ35	SRRM2	P42345	MTOR	T608	R602C	602	Missense	distal	-6	no	9.975	10.102	EPSD	TCGA;ICGC;COSMIC	6.822	Up-regulation
Atypical_PIKK_FRAP_MTOR_ST	Q9UQ35	SRRM2	P42345	MTOR	T608	S615F	615	Missense	distal	7	no	9.975	10.556	EPSD	TCGA	6.822	Up-regulation
Atypical_PIKK_FRAP_MTOR_ST	Q9UQ35	SRRM2	P42345	MTOR	T608	R601S	601	Missense	distal	-7	no	9.975	10.735	EPSD	TCGA;ICGC;COSMIC	6.822	Up-regulation
Atypical_PIKK_FRAP_MTOR_ST	Q9UQ35	SRRM2	P42345	MTOR	T608	R605W	605	Missense	distal	-3	no	9.975	9.760	EPSD	TCGA;ICGC;COSMIC;CCLE	6.822	Down-regulation
Atypical_PIKK_FRAP_MTOR_ST	Q9UQ35	SRRM2	P42345	MTOR	T608	R603K	603	Missense	distal	-5	no	9.975	9.820	EPSD	TCGA;ICGC	6.822	Down-regulation
Atypical_PIKK_FRAP_MTOR_ST	Q9UQ35	SRRM2	P42345	MTOR	T619	S615F	615	Missense	distal	-4	no	8.869	8.893	EPSD	TCGA	6.822	Up-regulation
Atypical_PIKK_FRAP_MTOR_ST	Q9UQ35	SRRM2	P42345	MTOR	T619	S617C	617	Missense	proximal	-2	no	8.869	9.018	EPSD	TCGA	6.822	Up-regulation
Atypical_PIKK_FRAP_MTOR_ST	Q9UQ35	SRRM2	P42345	MTOR	T619	R622S	622	Missense	distal	3	no	8.869	9.148	EPSD	TCGA;ICGC;COSMIC	6.822	Up-regulation
Atypical_PIKK_FRAP_MTOR_ST	Q9UQ35	SRRM2	P42345	MTOR	T619	R623H	623	Missense	distal	4	no	8.869	8.609	EPSD	TCGA;ICGC	6.822	Down-regulation
Atypical_PIKK_FRAP_MTOR_ST	Q9UQ35	SRRM2	P42345	MTOR	S629	S635F	635	Missense	distal	6	no	10.965	10.390	EPSD	TCGA;ICGC	6.822	Down-regulation
Atypical_PIKK_FRAP_MTOR_ST	Q9UQ35	SRRM2	P42345	MTOR	S629	R634S	634	Missense	distal	5	no	10.965	9.973	EPSD	TCGA;ICGC;COSMIC	6.822	Down-regulation
Atypical_PIKK_FRAP_MTOR_ST	Q9UQ35	SRRM2	P42345	MTOR	S629	R622S	622	Missense	distal	-7	no	10.965	11.724	EPSD	TCGA;ICGC;COSMIC	6.822	Up-regulation
Atypical_PIKK_FRAP_MTOR_ST	Q9UQ35	SRRM2	P42345	MTOR	S629	R632Q	632	Missense	distal	3	no	10.965	9.699	EPSD	TCGA;ICGC;COSMIC	6.822	Down-regulation
Atypical_PIKK_FRAP_MTOR_ST	Q9UQ35	SRRM2	P42345	MTOR	S629	R623H	623	Missense	distal	-6	no	10.965	10.159	EPSD	TCGA;ICGC	6.822	Down-regulation
Atypical_PIKK_FRAP_MTOR_ST	Q9UQ35	SRRM2	P42345	MTOR	S639	R643T	643	Missense	distal	4	no	15.180	15.820	EPSD	TCGA;ICGC;COSMIC	6.822	Up-regulation
Atypical_PIKK_FRAP_MTOR_ST	Q9UQ35	SRRM2	P42345	MTOR	S639	S635F	635	Missense	distal	-4	no	15.180	15.204	EPSD	TCGA;ICGC	6.822	Up-regulation
Atypical_PIKK_FRAP_MTOR_ST	Q9UQ35	SRRM2	P42345	MTOR	S639	S637C	637	Missense	proximal	-2	no	15.180	15.330	EPSD	TCGA;ICGC;COSMIC	6.822	Up-regulation
Atypical_PIKK_FRAP_MTOR_ST	Q9UQ35	SRRM2	P42345	MTOR	S639	R634S	634	Missense	distal	-5	no	15.180	15.038	EPSD	TCGA;ICGC;COSMIC	6.822	Down-regulation
Atypical_PIKK_FRAP_MTOR_ST	Q9UQ35	SRRM2	P42345	MTOR	S639	R632Q	632	Missense	distal	-7	no	15.180	15.102	EPSD	TCGA;ICGC;COSMIC	6.822	Down-regulation
Atypical_PIKK_FRAP_MTOR_ST	Q9UQ35	SRRM2	P42345	MTOR	T662	S669L	669	Missense	distal	7	no	7.283	8.260	EPSD	TCGA;ICGC;COSMIC	6.822	Up-regulation
Atypical_PIKK_FRAP_MTOR_ST	Q9UQ35	SRRM2	P42345	MTOR	T662	R668L	668	Missense	distal	6	no	7.283	7.916	EPSD	TCGA;ICGC;COSMIC	6.822	Up-regulation
Atypical_PIKK_FRAP_MTOR_ST	Q9UQ35	SRRM2	P42345	MTOR	T662	R659L	659	Missense	distal	-3	no	7.283	7.352	EPSD	TCGA;ICGC;COSMIC	6.822	Up-regulation
Atypical_PIKK_FRAP_MTOR_ST	Q9UQ35	SRRM2	P42345	MTOR	T696	R698K	698	Missense	proximal	2	no	5.990	7.636	EPSD	TCGA;ICGC;COSMIC	6.822	Gain
Atypical_PIKK_FRAP_MTOR_ST	Q9UQ35	SRRM2	P42345	MTOR	S706	R710C	710	Missense	distal	4	no	8.051	7.838	EPSD	TCGA;ICGC;COSMIC	6.822	Down-regulation
Atypical_PIKK_FRAP_MTOR_ST	Q9UQ35	SRRM2	P42345	MTOR	S727	G725D	725	Missense	proximal	-2	no	10.594	9.540	EPSD	TCGA;ICGC;COSMIC	6.822	Down-regulation
Atypical_PIKK_FRAP_MTOR_ST	Q9UQ35	SRRM2	P42345	MTOR	S727	R720I	720	Missense	distal	-7	no	10.594	10.346	EPSD	TCGA;ICGC;COSMIC	6.822	Down-regulation
Atypical_PIKK_FRAP_MTOR_ST	Q9UQ35	SRRM2	P42345	MTOR	S746	S743F	743	Missense	distal	-3	no	6.755	6.826	EPSD	TCGA;ICGC;COSMIC	6.822	Gain
Atypical_PIKK_FRAP_MTOR_ST	Q9UQ35	SRRM2	P42345	MTOR	S746	R753C	753	Missense	distal	7	no	6.755	7.185	EPSD	TCGA;ICGC;COSMIC	6.822	Gain
Atypical_PIKK_FRAP_MTOR_ST	Q9UQ35	SRRM2	P42345	MTOR	S761	L762V	762	Missense	proximal	1	no	9.676	8.924	EPSD	TCGA;ICGC;COSMIC	6.822	Down-regulation
Atypical_PIKK_FRAP_MTOR_ST	Q9UQ35	SRRM2	P42345	MTOR	S761	S755Y	755	Missense	distal	-6	no	9.676	8.806	EPSD	TCGA;ICGC;COSMIC	6.822	Down-regulation
Atypical_PIKK_FRAP_MTOR_ST	Q9UQ35	SRRM2	P42345	MTOR	S761	L762F	762	Missense	proximal	1	no	9.676	9.125	EPSD	TCGA;ICGC;COSMIC	6.822	Down-regulation
Atypical_PIKK_FRAP_MTOR_ST	Q9UQ35	SRRM2	P42345	MTOR	S761	S763C	763	Missense	proximal	2	no	9.676	8.130	EPSD	TCGA;COSMIC	6.822	Down-regulation
Atypical_PIKK_FRAP_MTOR_ST	Q9UQ35	SRRM2	P42345	MTOR	S761	R758Q	758	Missense	distal	-3	no	9.676	9.068	EPSD	TCGA;ICGC	6.822	Down-regulation
Atypical_PIKK_FRAP_MTOR_ST	Q9UQ35	SRRM2	P42345	MTOR	S761	S759R	759	Missense	proximal	-2	no	9.676	9.549	EPSD	TCGA;ICGC;COSMIC	6.822	Down-regulation
Atypical_PIKK_FRAP_MTOR_ST	Q9UQ35	SRRM2	P42345	MTOR	S761	R766Q	766	Missense	distal	5	no	9.676	8.869	EPSD	TCGA;ICGC;COSMIC	6.822	Down-regulation
Atypical_PIKK_FRAP_MTOR_ST	Q9UQ35	SRRM2	P42345	MTOR	S761	S756L	756	Missense	distal	-5	no	9.676	9.653	EPSD	TCGA;ICGC;COSMIC	6.822	Down-regulation
Atypical_PIKK_FRAP_MTOR_ST	Q9UQ35	SRRM2	P42345	MTOR	S761	I754M	754	Missense	distal	-7	no	9.676	10.094	EPSD	TCGA;ICGC;COSMIC	6.822	Up-regulation
Atypical_PIKK_FRAP_MTOR_ST	Q9UQ35	SRRM2	P42345	MTOR	S764	L762V	762	Missense	proximal	-2	no	10.278	10.494	EPSD	TCGA;ICGC;COSMIC	6.822	Up-regulation
Atypical_PIKK_FRAP_MTOR_ST	Q9UQ35	SRRM2	P42345	MTOR	S764	L762F	762	Missense	proximal	-2	no	10.278	10.591	EPSD	TCGA;ICGC;COSMIC	6.822	Up-regulation
Atypical_PIKK_FRAP_MTOR_ST	Q9UQ35	SRRM2	P42345	MTOR	S764	S763C	763	Missense	proximal	-1	no	10.278	10.289	EPSD	TCGA;COSMIC	6.822	Up-regulation
Atypical_PIKK_FRAP_MTOR_ST	Q9UQ35	SRRM2	P42345	MTOR	S764	R758Q	758	Missense	distal	-6	no	10.278	10.014	EPSD	TCGA;ICGC	6.822	Down-regulation
Atypical_PIKK_FRAP_MTOR_ST	Q9UQ35	SRRM2	P42345	MTOR	S764	S759R	759	Missense	distal	-5	no	10.278	10.419	EPSD	TCGA;ICGC;COSMIC	6.822	Up-regulation
Atypical_PIKK_FRAP_MTOR_ST	Q9UQ35	SRRM2	P42345	MTOR	S764	R766Q	766	Missense	proximal	2	no	10.278	10.266	EPSD	TCGA;ICGC;COSMIC	6.822	Down-regulation
Atypical_PIKK_FRAP_MTOR_ST	Q9UQ35	SRRM2	P42345	MTOR	S778	S783F	783	Missense	distal	5	no	7.398	7.984	EPSD	TCGA	6.822	Up-regulation
Atypical_PIKK_FRAP_MTOR_ST	Q9UQ35	SRRM2	P42345	MTOR	S778	R777H	777	Missense	proximal	-1	no	7.398	7.439	EPSD	TCGA;ICGC;COSMIC	6.822	Up-regulation
Atypical_PIKK_FRAP_MTOR_ST	Q9UQ35	SRRM2	P42345	MTOR	S778	S780L	780	Missense	proximal	2	no	7.398	7.203	EPSD	TCGA;ICGC;COSMIC	6.822	Down-regulation
Atypical_PIKK_FRAP_MTOR_ST	Q9UQ35	SRRM2	P42345	MTOR	S778	R772H	772	Missense	distal	-6	no	7.398	6.591	EPSD	TCGA;ICGC	6.822	Loss
Atypical_PIKK_FRAP_MTOR_ST	Q9UQ35	SRRM2	P42345	MTOR	S783	S783F	783	Missense	central	0	yes	10.880	0.000	EPSD	TCGA	6.822	Loss
Atypical_PIKK_FRAP_MTOR_ST	Q9UQ35	SRRM2	P42345	MTOR	S783	R777H	777	Missense	distal	-6	no	10.880	10.073	EPSD	TCGA;ICGC;COSMIC	6.822	Down-regulation
Atypical_PIKK_FRAP_MTOR_ST	Q9UQ35	SRRM2	P42345	MTOR	S783	S780L	780	Missense	distal	-3	no	10.880	11.295	EPSD	TCGA;ICGC;COSMIC	6.822	Up-regulation
Atypical_PIKK_FRAP_MTOR_ST	Q9UQ35	SRRM2	P42345	MTOR	T792	R795S	795	Missense	distal	3	no	8.079	8.358	EPSD	TCGA;ICGC;COSMIC	6.822	Up-regulation
Atypical_PIKK_FRAP_MTOR_ST	Q9UQ35	SRRM2	P42345	MTOR	T792	R796P	796	Missense	distal	4	no	8.079	8.396	EPSD	TCGA;ICGC;COSMIC	6.822	Up-regulation
Atypical_PIKK_FRAP_MTOR_ST	Q9UQ35	SRRM2	P42345	MTOR	T792	P793S	793	Missense	proximal	1	no	8.079	-0.445	EPSD	TCGA;ICGC;COSMIC	6.822	Loss
Atypical_PIKK_FRAP_MTOR_ST	Q9UQ35	SRRM2	P42345	MTOR	T792	R796H	796	Missense	distal	4	no	8.079	7.819	EPSD	TCGA;ICGC;COSMIC	6.822	Down-regulation
Atypical_PIKK_FRAP_MTOR_ST	Q9UQ35	SRRM2	P42345	MTOR	T810	S815I	815	Missense	distal	5	no	6.549	7.052	EPSD	TCGA;ICGC;COSMIC	6.822	Gain
Atypical_PIKK_FRAP_MTOR_ST	Q9UQ35	SRRM2	P42345	MTOR	S820	S815I	815	Missense	distal	-5	no	11.057	11.122	EPSD	TCGA;ICGC;COSMIC	6.822	Up-regulation
Atypical_PIKK_FRAP_MTOR_ST	Q9UQ35	SRRM2	P42345	MTOR	T829	S836F	836	Missense	distal	7	no	6.295	6.876	EPSD	TCGA;ICGC;COSMIC	6.822	Gain
Atypical_PIKK_FRAP_MTOR_ST	Q9UQ35	SRRM2	P42345	MTOR	T848	H841Y	841	Missense	distal	-7	no	8.438	9.457	EPSD	TCGA;ICGC;COSMIC	6.822	Up-regulation
Atypical_PIKK_FRAP_MTOR_ST	Q9UQ35	SRRM2	P42345	MTOR	T866	V865L	865	Missense	proximal	-1	no	7.535	7.412	EPSD	TCGA;ICGC;COSMIC	6.822	Down-regulation
Atypical_PIKK_FRAP_MTOR_ST	Q9UQ35	SRRM2	P42345	MTOR	T866	R870W	870	Missense	distal	4	no	7.535	7.697	EPSD	TCGA;ICGC;COSMIC	6.822	Up-regulation
Atypical_PIKK_FRAP_MTOR_ST	Q9UQ35	SRRM2	P42345	MTOR	S876	P877L	877	Missense	proximal	1	no	8.686	2.716	EPSD	TCGA;ICGC;COSMIC	6.822	Loss
Atypical_PIKK_FRAP_MTOR_ST	Q9UQ35	SRRM2	P42345	MTOR	S876	R870W	870	Missense	distal	-6	no	8.686	9.058	EPSD	TCGA;ICGC;COSMIC	6.822	Up-regulation
Atypical_PIKK_FRAP_MTOR_ST	Q9UQ35	SRRM2	P42345	MTOR	T885	T885A	885	Missense	central	0	yes	11.329	0.000	EPSD	TCGA;ICGC;COSMIC	6.822	Loss
Atypical_PIKK_FRAP_MTOR_ST	Q9UQ35	SRRM2	P42345	MTOR	S908	S914F	914	Missense	distal	6	no	8.321	7.746	EPSD	TCGA;ICGC	6.822	Down-regulation
Atypical_PIKK_FRAP_MTOR_ST	Q9UQ35	SRRM2	P42345	MTOR	S935	S931F	931	Missense	distal	-4	no	11.289	11.313	EPSD	TCGA;ICGC;COSMIC	6.822	Up-regulation
Atypical_PIKK_FRAP_MTOR_ST	Q9UQ35	SRRM2	P42345	MTOR	S935	T942M	942	Missense	distal	7	no	11.289	12.375	EPSD	TCGA;ICGC;COSMIC	6.822	Up-regulation
Atypical_PIKK_FRAP_MTOR_ST	Q9UQ35	SRRM2	P42345	MTOR	S935	R928I	928	Missense	distal	-7	no	11.289	11.042	EPSD	TCGA	6.822	Down-regulation
Atypical_PIKK_FRAP_MTOR_ST	Q9UQ35	SRRM2	P42345	MTOR	S937	S931F	931	Missense	distal	-6	no	9.099	8.624	EPSD	TCGA;ICGC;COSMIC	6.822	Down-regulation
Atypical_PIKK_FRAP_MTOR_ST	Q9UQ35	SRRM2	P42345	MTOR	S937	T942M	942	Missense	distal	5	no	9.099	9.363	EPSD	TCGA;ICGC;COSMIC	6.822	Up-regulation
Atypical_PIKK_FRAP_MTOR_ST	Q9UQ35	SRRM2	P42345	MTOR	S937	R944G	944	Missense	distal	7	no	9.099	8.691	EPSD	TCGA;ICGC;COSMIC	6.822	Down-regulation
Atypical_PIKK_FRAP_MTOR_ST	Q9UQ35	SRRM2	P42345	MTOR	S954	R948Q	948	Missense	distal	-6	no	10.223	9.959	EPSD	TCGA;ICGC;COSMIC	6.822	Down-regulation
Atypical_PIKK_FRAP_MTOR_ST	Q9UQ35	SRRM2	P42345	MTOR	S954	E960K	960	Missense	distal	6	no	10.223	9.319	EPSD	TCGA;ICGC;COSMIC	6.822	Down-regulation
Atypical_PIKK_FRAP_MTOR_ST	Q9UQ35	SRRM2	P42345	MTOR	S974	P981S	981	Missense	distal	7	no	14.879	14.858	EPSD	TCGA;ICGC;COSMIC	6.822	Down-regulation
Atypical_PIKK_FRAP_MTOR_ST	Q9UQ35	SRRM2	P42345	MTOR	S974	G971E	971	Missense	distal	-3	no	14.879	14.133	EPSD	TCGA;ICGC	6.822	Down-regulation
Atypical_PIKK_FRAP_MTOR_ST	Q9UQ35	SRRM2	P42345	MTOR	T983	P981S	981	Missense	proximal	-2	no	7.957	7.601	EPSD	TCGA;ICGC;COSMIC	6.822	Down-regulation
Atypical_PIKK_FRAP_MTOR_ST	Q9UQ35	SRRM2	P42345	MTOR	T983	H989Y	989	Missense	distal	6	no	7.957	8.031	EPSD	TCGA;ICGC;COSMIC;GDSC;CCLE	6.822	Up-regulation
Atypical_PIKK_FRAP_MTOR_ST	Q9UQ35	SRRM2	P42345	MTOR	S994	G991V	991	Missense	distal	-3	no	8.813	8.577	EPSD	TCGA;ICGC;COSMIC	6.822	Down-regulation
Atypical_PIKK_FRAP_MTOR_ST	Q9UQ35	SRRM2	P42345	MTOR	S994	H989Y	989	Missense	distal	-5	no	8.813	9.161	EPSD	TCGA;ICGC;COSMIC;GDSC;CCLE	6.822	Up-regulation
Atypical_PIKK_FRAP_MTOR_ST	Q9UQ35	SRRM2	P42345	MTOR	S994	G991E	991	Missense	distal	-3	no	8.813	8.067	EPSD	TCGA;ICGC	6.822	Down-regulation
Atypical_PIKK_FRAP_MTOR_ST	Q9UQ35	SRRM2	P42345	MTOR	S1028	S1032F	1032	Missense	distal	4	no	7.441	7.197	EPSD	TCGA;ICGC;COSMIC	6.822	Down-regulation
Atypical_PIKK_FRAP_MTOR_ST	Q9UQ35	SRRM2	P42345	MTOR	S1042	E1047K	1047	Missense	distal	5	no	8.879	8.934	EPSD	TCGA;ICGC;COSMIC;GDSC	6.822	Up-regulation
Atypical_PIKK_FRAP_MTOR_ST	Q9UQ35	SRRM2	P42345	MTOR	S1042	S1041Y	1041	Missense	proximal	-1	no	8.879	8.706	EPSD	TCGA;ICGC;COSMIC	6.822	Down-regulation
Atypical_PIKK_FRAP_MTOR_ST	Q9UQ35	SRRM2	P42345	MTOR	S1048	L1055V	1055	Missense	distal	7	no	7.414	6.949	EPSD	TCGA;ICGC;COSMIC	6.822	Down-regulation
Atypical_PIKK_FRAP_MTOR_ST	Q9UQ35	SRRM2	P42345	MTOR	S1048	E1047K	1047	Missense	proximal	-1	no	7.414	7.325	EPSD	TCGA;ICGC;COSMIC;GDSC	6.822	Down-regulation
Atypical_PIKK_FRAP_MTOR_ST	Q9UQ35	SRRM2	P42345	MTOR	S1048	S1041Y	1041	Missense	distal	-7	no	7.414	7.325	EPSD	TCGA;ICGC;COSMIC	6.822	Down-regulation
Atypical_PIKK_FRAP_MTOR_ST	Q9UQ35	SRRM2	P42345	MTOR	S1073	P1074S	1074	Missense	proximal	1	no	9.445	0.921	EPSD	TCGA;ICGC;COSMIC	6.822	Loss
Atypical_PIKK_FRAP_MTOR_ST	Q9UQ35	SRRM2	P42345	MTOR	S1073	R1077T	1077	Missense	distal	4	no	9.445	10.085	EPSD	TCGA;ICGC;COSMIC	6.822	Up-regulation
Atypical_PIKK_FRAP_MTOR_ST	Q9UQ35	SRRM2	P42345	MTOR	S1073	D1070H	1070	Missense	distal	-3	no	9.445	8.919	EPSD	TCGA;ICGC;COSMIC	6.822	Down-regulation
Atypical_PIKK_FRAP_MTOR_ST	Q9UQ35	SRRM2	P42345	MTOR	S1073	P1074L	1074	Missense	proximal	1	no	9.445	3.476	EPSD	TCGA;ICGC;COSMIC	6.822	Loss
Atypical_PIKK_FRAP_MTOR_ST	Q9UQ35	SRRM2	P42345	MTOR	S1073	S1073N	1073	Missense	central	0	yes	9.445	0.000	EPSD	TCGA;ICGC;COSMIC	6.822	Loss
Atypical_PIKK_FRAP_MTOR_ST	Q9UQ35	SRRM2	P42345	MTOR	S1103	E1107D	1107	Missense	distal	4	no	8.453	8.614	EPSD	TCGA;ICGC;COSMIC	6.822	Up-regulation
Atypical_PIKK_FRAP_MTOR_ST	Q9UQ35	SRRM2	P42345	MTOR	S1124	F1121L	1121	Missense	distal	-3	no	9.039	9.383	EPSD	TCGA;ICGC;COSMIC	6.822	Up-regulation
Atypical_PIKK_FRAP_MTOR_ST	Q9UQ35	SRRM2	P42345	MTOR	S1124	A1123V	1123	Missense	proximal	-1	no	9.039	8.966	EPSD	TCGA;ICGC;COSMIC	6.822	Down-regulation
Atypical_PIKK_FRAP_MTOR_ST	Q9UQ35	SRRM2	P42345	MTOR	S1124	G1119S	1119	Missense	distal	-5	no	9.039	8.971	EPSD	TCGA;ICGC;COSMIC	6.822	Down-regulation
Atypical_PIKK_FRAP_MTOR_ST	Q9UQ35	SRRM2	P42345	MTOR	S1124	S1129F	1129	Missense	distal	5	no	9.039	9.625	EPSD	TCGA;ICGC;COSMIC	6.822	Up-regulation
Atypical_PIKK_FRAP_MTOR_ST	Q9UQ35	SRRM2	P42345	MTOR	S1132	R1137K	1137	Missense	distal	5	no	11.262	9.941	EPSD	TCGA	6.822	Down-regulation
Atypical_PIKK_FRAP_MTOR_ST	Q9UQ35	SRRM2	P42345	MTOR	S1132	Q1139P	1139	Missense	distal	7	no	11.262	10.889	EPSD	TCGA;ICGC;COSMIC	6.822	Down-regulation
Atypical_PIKK_FRAP_MTOR_ST	Q9UQ35	SRRM2	P42345	MTOR	S1132	S1129F	1129	Missense	distal	-3	no	11.262	11.333	EPSD	TCGA;ICGC;COSMIC	6.822	Up-regulation
Atypical_PIKK_FRAP_MTOR_ST	Q9UQ35	SRRM2	P42345	MTOR	S1132	P1133L	1133	Missense	proximal	1	no	11.262	5.292	EPSD	TCGA;ICGC;COSMIC	6.822	Loss
Atypical_PIKK_FRAP_MTOR_ST	Q9UQ35	SRRM2	P42345	MTOR	S1132	E1134K	1134	Missense	proximal	2	no	11.262	10.356	EPSD	TCGA;ICGC;COSMIC	6.822	Down-regulation
Atypical_PIKK_FRAP_MTOR_ST	Q9UQ35	SRRM2	P42345	MTOR	S1132	R1137M	1137	Missense	distal	5	no	11.262	10.136	EPSD	TCGA;ICGC;COSMIC	6.822	Down-regulation
Atypical_PIKK_FRAP_MTOR_ST	Q9UQ35	SRRM2	P42345	MTOR	S1132	S1132Y	1132	Missense	central	0	yes	11.262	0.000	EPSD	TCGA;ICGC	6.822	Loss
Atypical_PIKK_FRAP_MTOR_ST	Q9UQ35	SRRM2	P42345	MTOR	S1144	R1137K	1137	Missense	distal	-7	no	9.835	9.981	EPSD	TCGA	6.822	Up-regulation
Atypical_PIKK_FRAP_MTOR_ST	Q9UQ35	SRRM2	P42345	MTOR	S1144	P1146R	1146	Missense	proximal	2	no	9.835	7.628	EPSD	TCGA;ICGC;COSMIC	6.822	Down-regulation
Atypical_PIKK_FRAP_MTOR_ST	Q9UQ35	SRRM2	P42345	MTOR	S1144	Q1139P	1139	Missense	distal	-5	no	9.835	9.827	EPSD	TCGA;ICGC;COSMIC	6.822	Down-regulation
Atypical_PIKK_FRAP_MTOR_ST	Q9UQ35	SRRM2	P42345	MTOR	S1144	S1150L	1150	Missense	distal	6	no	9.835	8.646	EPSD	TCGA;ICGC;COSMIC;CCLE	6.822	Down-regulation
Atypical_PIKK_FRAP_MTOR_ST	Q9UQ35	SRRM2	P42345	MTOR	S1144	R1137M	1137	Missense	distal	-7	no	9.835	10.006	EPSD	TCGA;ICGC;COSMIC	6.822	Up-regulation
Atypical_PIKK_FRAP_MTOR_ST	Q9UQ35	SRRM2	P42345	MTOR	S1157	S1150L	1150	Missense	distal	-7	no	8.247	7.677	EPSD	TCGA;ICGC;COSMIC;CCLE	6.822	Down-regulation
Atypical_PIKK_FRAP_MTOR_ST	Q9UQ35	SRRM2	P42345	MTOR	S1179	R1182G	1182	Missense	distal	3	no	7.467	8.815	EPSD	TCGA;ICGC;COSMIC	6.822	Up-regulation
Atypical_PIKK_FRAP_MTOR_ST	Q9UQ35	SRRM2	P42345	MTOR	S1179	K1184N	1184	Missense	distal	5	no	7.467	9.277	EPSD	TCGA;ICGC;COSMIC	6.822	Up-regulation
Atypical_PIKK_FRAP_MTOR_ST	Q9UQ35	SRRM2	P42345	MTOR	S1179	A1178V	1178	Missense	proximal	-1	no	7.467	7.395	EPSD	TCGA;ICGC;COSMIC	6.822	Down-regulation
Atypical_PIKK_FRAP_MTOR_ST	Q9UQ35	SRRM2	P42345	MTOR	S1179	P1181R	1181	Missense	proximal	2	no	7.467	5.260	EPSD	TCGA;ICGC;COSMIC	6.822	Loss
Atypical_PIKK_FRAP_MTOR_ST	Q9UQ35	SRRM2	P42345	MTOR	S1179	T1177A	1177	Missense	proximal	-2	no	7.467	7.964	EPSD	TCGA;ICGC;COSMIC	6.822	Up-regulation
Atypical_PIKK_FRAP_MTOR_ST	Q9UQ35	SRRM2	P42345	MTOR	T1208	E1212Q	1212	Missense	distal	4	no	9.552	9.343	EPSD	TCGA;ICGC;COSMIC	6.822	Down-regulation
Atypical_PIKK_FRAP_MTOR_ST	Q9UQ35	SRRM2	P42345	MTOR	T1208	R1207S	1207	Missense	proximal	-1	no	9.552	9.714	EPSD	TCGA;ICGC;COSMIC	6.822	Up-regulation
Atypical_PIKK_FRAP_MTOR_ST	Q9UQ35	SRRM2	P42345	MTOR	S1219	E1212Q	1212	Missense	distal	-7	no	7.728	7.296	EPSD	TCGA;ICGC;COSMIC	6.822	Down-regulation
Atypical_PIKK_FRAP_MTOR_ST	Q9UQ35	SRRM2	P42345	MTOR	S1326	G1328E	1328	Missense	proximal	2	no	9.156	10.174	EPSD;PhosphoSitePlus	TCGA;ICGC	6.822	Up-regulation
Atypical_PIKK_FRAP_MTOR_ST	Q9UQ35	SRRM2	P42345	MTOR	S1329	G1328E	1328	Missense	proximal	-1	no	11.880	11.855	PhosphoSitePlus;EPSD	TCGA;ICGC	6.822	Down-regulation
Atypical_PIKK_FRAP_MTOR_ST	Q9UQ35	SRRM2	P42345	MTOR	S1387	A1394T	1394	Missense	distal	7	no	9.596	9.075	EPSD	TCGA;ICGC;COSMIC	6.822	Down-regulation
Atypical_PIKK_FRAP_MTOR_ST	Q9UQ35	SRRM2	P42345	MTOR	S1387	V1391M	1391	Missense	distal	4	no	9.596	9.761	EPSD	TCGA;ICGC;COSMIC;GDSC;CCLE	6.822	Up-regulation
Atypical_PIKK_FRAP_MTOR_ST	Q9UQ35	SRRM2	P42345	MTOR	S1387	S1383G	1383	Missense	distal	-4	no	9.596	9.029	EPSD	TCGA;ICGC;COSMIC	6.822	Down-regulation
Atypical_PIKK_FRAP_MTOR_ST	Q9UQ35	SRRM2	P42345	MTOR	T1413	D1408H	1408	Missense	distal	-5	no	7.731	7.922	EPSD	TCGA;ICGC;COSMIC	6.822	Up-regulation
Atypical_PIKK_FRAP_MTOR_ST	Q9UQ35	SRRM2	P42345	MTOR	T1413	A1409V	1409	Missense	distal	-4	no	7.731	8.011	EPSD	TCGA;ICGC;COSMIC	6.822	Up-regulation
Atypical_PIKK_FRAP_MTOR_ST	Q9UQ35	SRRM2	P42345	MTOR	T1413	R1412I	1412	Missense	proximal	-1	no	7.731	7.656	EPSD	TCGA;ICGC;COSMIC	6.822	Down-regulation
Atypical_PIKK_FRAP_MTOR_ST	Q9UQ35	SRRM2	P42345	MTOR	S1423	G1430V	1430	Missense	distal	7	no	6.768	6.897	EPSD	TCGA;ICGC;COSMIC	6.822	Gain
Atypical_PIKK_FRAP_MTOR_ST	Q9UQ35	SRRM2	P42345	MTOR	S1423	S1424P	1424	Missense	proximal	1	no	6.768	15.292	EPSD	TCGA;ICGC;COSMIC	6.822	Gain
Atypical_PIKK_FRAP_MTOR_ST	Q9UQ35	SRRM2	P42345	MTOR	S1424	D1429H	1429	Missense	distal	5	no	11.400	12.662	EPSD	TCGA;ICGC;COSMIC	6.822	Up-regulation
Atypical_PIKK_FRAP_MTOR_ST	Q9UQ35	SRRM2	P42345	MTOR	S1424	M1427I	1427	Missense	distal	3	no	11.400	11.568	EPSD	TCGA;ICGC;COSMIC	6.822	Up-regulation
Atypical_PIKK_FRAP_MTOR_ST	Q9UQ35	SRRM2	P42345	MTOR	S1424	G1430V	1430	Missense	distal	6	no	11.400	11.511	EPSD	TCGA;ICGC;COSMIC	6.822	Up-regulation
Atypical_PIKK_FRAP_MTOR_ST	Q9UQ35	SRRM2	P42345	MTOR	S1424	S1424P	1424	Missense	central	0	yes	11.400	0.000	EPSD	TCGA;ICGC;COSMIC	6.822	Loss
Atypical_PIKK_FRAP_MTOR_ST	Q9UQ35	SRRM2	P42345	MTOR	S1444	R1448T	1448	Missense	distal	4	no	12.094	12.734	EPSD	TCGA;ICGC;COSMIC	6.822	Up-regulation
Atypical_PIKK_FRAP_MTOR_ST	Q9UQ35	SRRM2	P42345	MTOR	S1444	P1445R	1445	Missense	proximal	1	no	12.094	2.260	EPSD	TCGA;ICGC;COSMIC	6.822	Loss
Atypical_PIKK_FRAP_MTOR_ST	Q9UQ35	SRRM2	P42345	MTOR	S1444	G1446E	1446	Missense	proximal	2	no	12.094	13.112	EPSD	TCGA;ICGC	6.822	Up-regulation
Atypical_PIKK_FRAP_MTOR_ST	Q9UQ35	SRRM2	P42345	MTOR	S1444	D1449N	1449	Missense	distal	5	no	12.094	13.540	EPSD	TCGA;ICGC	6.822	Up-regulation
Atypical_PIKK_FRAP_MTOR_ST	Q9UQ35	SRRM2	P42345	MTOR	T1453	R1448T	1448	Missense	distal	-5	no	11.406	11.271	EPSD	TCGA;ICGC;COSMIC	6.822	Down-regulation
Atypical_PIKK_FRAP_MTOR_ST	Q9UQ35	SRRM2	P42345	MTOR	T1453	G1446E	1446	Missense	distal	-7	no	11.406	11.564	EPSD	TCGA;ICGC	6.822	Up-regulation
Atypical_PIKK_FRAP_MTOR_ST	Q9UQ35	SRRM2	P42345	MTOR	T1453	D1449N	1449	Missense	distal	-4	no	11.406	9.246	EPSD	TCGA;ICGC	6.822	Down-regulation
Atypical_PIKK_FRAP_MTOR_ST	Q9UQ35	SRRM2	P42345	MTOR	T1472	E1479A	1479	Missense	distal	7	no	11.668	11.693	EPSD	TCGA;ICGC;COSMIC	6.822	Up-regulation
Atypical_PIKK_FRAP_MTOR_ST	Q9UQ35	SRRM2	P42345	MTOR	T1472	R1475T	1475	Missense	distal	3	no	11.668	11.541	EPSD	TCGA;ICGC;COSMIC	6.822	Down-regulation
Atypical_PIKK_FRAP_MTOR_ST	Q9UQ35	SRRM2	P42345	MTOR	T1472	T1472M	1472	Missense	central	0	yes	11.668	0.000	EPSD	TCGA;ICGC;COSMIC	6.822	Loss
Atypical_PIKK_FRAP_MTOR_ST	Q9UQ35	SRRM2	P42345	MTOR	S1483	E1479A	1479	Missense	distal	-4	no	7.968	7.126	EPSD	TCGA;ICGC;COSMIC	6.822	Down-regulation
Atypical_PIKK_FRAP_MTOR_ST	Q9UQ35	SRRM2	P42345	MTOR	S1483	D1481N	1481	Missense	proximal	-2	no	7.968	7.701	EPSD	TCGA;ICGC;COSMIC	6.822	Down-regulation
Atypical_PIKK_FRAP_MTOR_ST	Q9UQ35	SRRM2	P42345	MTOR	T1492	P1493R	1493	Missense	proximal	1	no	7.770	-2.064	EPSD	TCGA;ICGC;COSMIC	6.822	Loss
Atypical_PIKK_FRAP_MTOR_ST	Q9UQ35	SRRM2	P42345	MTOR	S1499	L1505P	1505	Missense	distal	6	no	12.458	13.617	EPSD	TCGA;ICGC;COSMIC	6.822	Up-regulation
Atypical_PIKK_FRAP_MTOR_ST	Q9UQ35	SRRM2	P42345	MTOR	S1499	S1501L	1501	Missense	proximal	2	no	12.458	12.263	EPSD	TCGA;ICGC;COSMIC	6.822	Down-regulation
Atypical_PIKK_FRAP_MTOR_ST	Q9UQ35	SRRM2	P42345	MTOR	S1499	P1493R	1493	Missense	distal	-6	no	12.458	12.544	EPSD	TCGA;ICGC;COSMIC	6.822	Up-regulation
Atypical_PIKK_FRAP_MTOR_ST	Q9UQ35	SRRM2	P42345	MTOR	S1499	S1501A	1501	Missense	proximal	2	no	12.458	11.694	EPSD	TCGA;ICGC	6.822	Down-regulation
Atypical_PIKK_FRAP_MTOR_ST	Q9UQ35	SRRM2	P42345	MTOR	S1502	L1505P	1505	Missense	distal	3	no	8.077	10.331	EPSD	TCGA;ICGC;COSMIC	6.822	Up-regulation
Atypical_PIKK_FRAP_MTOR_ST	Q9UQ35	SRRM2	P42345	MTOR	S1502	S1501L	1501	Missense	proximal	-1	no	8.077	7.875	EPSD	TCGA;ICGC;COSMIC	6.822	Down-regulation
Atypical_PIKK_FRAP_MTOR_ST	Q9UQ35	SRRM2	P42345	MTOR	S1502	C1509Y	1509	Missense	distal	7	no	8.077	6.455	EPSD	TCGA;ICGC;COSMIC	6.822	Loss
Atypical_PIKK_FRAP_MTOR_ST	Q9UQ35	SRRM2	P42345	MTOR	S1502	S1501A	1501	Missense	proximal	-1	no	8.077	8.071	EPSD	TCGA;ICGC	6.822	Down-regulation
Atypical_PIKK_FRAP_MTOR_ST	Q9UQ35	SRRM2	P42345	MTOR	T1511	E1515Q	1515	Missense	distal	4	no	8.008	7.799	EPSD	TCGA;ICGC;COSMIC	6.822	Down-regulation
Atypical_PIKK_FRAP_MTOR_ST	Q9UQ35	SRRM2	P42345	MTOR	T1511	T1511I	1511	Missense	central	0	yes	8.008	0.000	EPSD	TCGA;ICGC;COSMIC	6.822	Loss
Atypical_PIKK_FRAP_MTOR_ST	Q9UQ35	SRRM2	P42345	MTOR	T1511	L1505P	1505	Missense	distal	-6	no	8.008	8.783	EPSD	TCGA;ICGC;COSMIC	6.822	Up-regulation
Atypical_PIKK_FRAP_MTOR_ST	Q9UQ35	SRRM2	P42345	MTOR	T1511	C1509Y	1509	Missense	proximal	-2	no	8.008	7.316	EPSD	TCGA;ICGC;COSMIC	6.822	Down-regulation
Atypical_PIKK_FRAP_MTOR_ST	Q9UQ35	SRRM2	P42345	MTOR	T1531	R1538C	1538	Missense	distal	7	no	13.389	13.819	EPSD	TCGA;ICGC;COSMIC	6.822	Up-regulation
Atypical_PIKK_FRAP_MTOR_ST	Q9UQ35	SRRM2	P42345	MTOR	T1531	P1532L	1532	Missense	proximal	1	no	13.389	7.420	EPSD	TCGA;ICGC;COSMIC	6.822	Down-regulation
Atypical_PIKK_FRAP_MTOR_ST	Q9UQ35	SRRM2	P42345	MTOR	T1531	K1526E	1526	Missense	distal	-5	no	13.389	13.097	EPSD	TCGA;ICGC;COSMIC	6.822	Down-regulation
Atypical_PIKK_FRAP_MTOR_ST	Q9UQ35	SRRM2	P42345	MTOR	S1559	S1565Y	1565	Missense	distal	6	no	6.938	5.505	EPSD	TCGA;ICGC;COSMIC	6.822	Loss
Atypical_PIKK_FRAP_MTOR_ST	Q9UQ35	SRRM2	P42345	MTOR	T1571	R1570K	1570	Missense	proximal	-1	no	9.712	9.754	EPSD	TCGA;ICGC	6.822	Up-regulation
Atypical_PIKK_FRAP_MTOR_ST	Q9UQ35	SRRM2	P42345	MTOR	T1571	S1565Y	1565	Missense	distal	-6	no	9.712	8.842	EPSD	TCGA;ICGC;COSMIC	6.822	Down-regulation
Atypical_PIKK_FRAP_MTOR_ST	Q9UQ35	SRRM2	P42345	MTOR	S1582	S1581L	1581	Missense	proximal	-1	no	10.483	10.281	EPSD	TCGA;ICGC;COSMIC	6.822	Down-regulation
Atypical_PIKK_FRAP_MTOR_ST	Q9UQ35	SRRM2	P42345	MTOR	S1620	P1627L	1627	Missense	distal	7	no	5.907	6.864	EPSD	TCGA;ICGC;COSMIC	6.822	Gain
Atypical_PIKK_FRAP_MTOR_ST	Q9UQ35	SRRM2	P42345	MTOR	S1621	P1627L	1627	Missense	distal	6	no	8.173	7.014	EPSD	TCGA;ICGC;COSMIC	6.822	Down-regulation
Atypical_PIKK_FRAP_MTOR_ST	Q9UQ35	SRRM2	P42345	MTOR	S1621	P1622S	1622	Missense	proximal	1	no	8.173	-0.351	EPSD	TCGA;ICGC;COSMIC	6.822	Loss
Atypical_PIKK_FRAP_MTOR_ST	Q9UQ35	SRRM2	P42345	MTOR	S1648	R1645K	1645	Missense	distal	-3	no	14.914	14.199	EPSD	TCGA;ICGC;COSMIC	6.822	Down-regulation
Atypical_PIKK_FRAP_MTOR_ST	Q9UQ35	SRRM2	P42345	MTOR	S1648	P1647L	1647	Missense	proximal	-1	no	14.914	14.780	EPSD	TCGA;ICGC;COSMIC	6.822	Down-regulation
Atypical_PIKK_FRAP_MTOR_ST	Q9UQ35	SRRM2	P42345	MTOR	S1648	S1648Y	1648	Missense	central	0	yes	14.914	0.000	EPSD	TCGA;ICGC;COSMIC	6.822	Loss
Atypical_PIKK_FRAP_MTOR_ST	Q9UQ35	SRRM2	P42345	MTOR	S1654	P1647L	1647	Missense	distal	-7	no	9.153	9.021	EPSD	TCGA;ICGC;COSMIC	6.822	Down-regulation
Atypical_PIKK_FRAP_MTOR_ST	Q9UQ35	SRRM2	P42345	MTOR	S1654	S1648Y	1648	Missense	distal	-6	no	9.153	8.283	EPSD	TCGA;ICGC;COSMIC	6.822	Down-regulation
Atypical_PIKK_FRAP_MTOR_ST	Q9UQ35	SRRM2	P42345	MTOR	S1675	P1678R	1678	Missense	distal	3	no	7.276	7.011	EPSD	TCGA;ICGC;COSMIC	6.822	Down-regulation
Atypical_PIKK_FRAP_MTOR_ST	Q9UQ35	SRRM2	P42345	MTOR	S1675	S1674L	1674	Missense	proximal	-1	no	7.276	7.074	EPSD	TCGA;ICGC;COSMIC	6.822	Down-regulation
Atypical_PIKK_FRAP_MTOR_ST	Q9UQ35	SRRM2	P42345	MTOR	S1675	R1673G	1673	Missense	proximal	-2	no	7.276	8.134	EPSD	TCGA	6.822	Up-regulation
Atypical_PIKK_FRAP_MTOR_ST	Q9UQ35	SRRM2	P42345	MTOR	T1684	P1678R	1678	Missense	distal	-6	no	8.317	8.404	EPSD	TCGA;ICGC;COSMIC	6.822	Up-regulation
Atypical_PIKK_FRAP_MTOR_ST	Q9UQ35	SRRM2	P42345	MTOR	S1694	R1692Q	1692	Missense	proximal	-2	no	11.187	11.526	EPSD	TCGA;ICGC;COSMIC;GDSC;CCLE	6.822	Up-regulation
Atypical_PIKK_FRAP_MTOR_ST	Q9UQ35	SRRM2	P42345	MTOR	S1713	R1719I	1719	Missense	distal	6	no	8.910	9.869	EPSD	TCGA;ICGC;COSMIC	6.822	Up-regulation
Atypical_PIKK_FRAP_MTOR_ST	Q9UQ35	SRRM2	P42345	MTOR	S1713	R1717H	1717	Missense	distal	4	no	8.910	8.651	EPSD	TCGA;ICGC;COSMIC	6.822	Down-regulation
Atypical_PIKK_FRAP_MTOR_ST	Q9UQ35	SRRM2	P42345	MTOR	S1713	S1718C	1718	Missense	distal	5	no	8.910	9.687	EPSD	TCGA;ICGC;COSMIC	6.822	Up-regulation
Atypical_PIKK_FRAP_MTOR_ST	Q9UQ35	SRRM2	P42345	MTOR	S1713	R1708C	1708	Missense	distal	-5	no	8.910	9.034	EPSD	TCGA;ICGC;COSMIC	6.822	Up-regulation
Atypical_PIKK_FRAP_MTOR_ST	Q9UQ35	SRRM2	P42345	MTOR	T1720	R1719I	1719	Missense	proximal	-1	no	7.016	6.941	EPSD	TCGA;ICGC;COSMIC	6.822	Down-regulation
Atypical_PIKK_FRAP_MTOR_ST	Q9UQ35	SRRM2	P42345	MTOR	T1720	R1717H	1717	Missense	distal	-3	no	7.016	6.269	EPSD	TCGA;ICGC;COSMIC	6.822	Loss
Atypical_PIKK_FRAP_MTOR_ST	Q9UQ35	SRRM2	P42345	MTOR	T1720	S1718C	1718	Missense	proximal	-2	no	7.016	7.165	EPSD	TCGA;ICGC;COSMIC	6.822	Up-regulation
Atypical_PIKK_FRAP_MTOR_ST	Q9UQ35	SRRM2	P42345	MTOR	S1727	S1731F	1731	Missense	distal	4	no	10.374	10.130	EPSD	TCGA;ICGC;COSMIC	6.822	Down-regulation
Atypical_PIKK_FRAP_MTOR_ST	Q9UQ35	SRRM2	P42345	MTOR	S1727	P1728L	1728	Missense	proximal	1	no	10.374	4.405	EPSD	TCGA;ICGC;COSMIC	6.822	Loss
Atypical_PIKK_FRAP_MTOR_ST	Q9UQ35	SRRM2	P42345	MTOR	S1732	S1731F	1731	Missense	proximal	-1	no	10.028	9.844	EPSD	TCGA;ICGC;COSMIC	6.822	Down-regulation
Atypical_PIKK_FRAP_MTOR_ST	Q9UQ35	SRRM2	P42345	MTOR	S1732	S1739L	1739	Missense	distal	7	no	10.028	11.005	EPSD	TCGA;ICGC;COSMIC	6.822	Up-regulation
Atypical_PIKK_FRAP_MTOR_ST	Q9UQ35	SRRM2	P42345	MTOR	S1732	P1728L	1728	Missense	distal	-4	no	10.028	9.842	EPSD	TCGA;ICGC;COSMIC	6.822	Down-regulation
Atypical_PIKK_FRAP_MTOR_ST	Q9UQ35	SRRM2	P42345	MTOR	S1762	S1764L	1764	Missense	proximal	2	no	10.436	10.241	EPSD	TCGA;ICGC;COSMIC	6.822	Down-regulation
Atypical_PIKK_FRAP_MTOR_ST	Q9UQ35	SRRM2	P42345	MTOR	S1762	R1761C	1761	Missense	proximal	-1	no	10.436	10.609	EPSD	TCGA;ICGC;COSMIC	6.822	Up-regulation
Atypical_PIKK_FRAP_MTOR_ST	Q9UQ35	SRRM2	P42345	MTOR	S1764	S1764L	1764	Missense	central	0	yes	10.855	0.000	EPSD	TCGA;ICGC;COSMIC	6.822	Loss
Atypical_PIKK_FRAP_MTOR_ST	Q9UQ35	SRRM2	P42345	MTOR	S1764	R1761C	1761	Missense	distal	-3	no	10.855	10.143	EPSD	TCGA;ICGC;COSMIC	6.822	Down-regulation
Atypical_PIKK_FRAP_MTOR_ST	Q9UQ35	SRRM2	P42345	MTOR	S1824	S1830N	1830	Missense	distal	6	no	8.458	7.225	EPSD	TCGA;ICGC;COSMIC	6.822	Down-regulation
Atypical_PIKK_FRAP_MTOR_ST	Q9UQ35	SRRM2	P42345	MTOR	S1824	G1819D	1819	Missense	distal	-5	no	8.458	8.346	EPSD	TCGA;ICGC;COSMIC	6.822	Down-regulation
Atypical_PIKK_FRAP_MTOR_ST	Q9UQ35	SRRM2	P42345	MTOR	S1824	R1827W	1827	Missense	distal	3	no	8.458	6.699	EPSD	TCGA;ICGC;COSMIC;CCLE	6.822	Loss
Atypical_PIKK_FRAP_MTOR_ST	Q9UQ35	SRRM2	P42345	MTOR	S1824	H1821Y	1821	Missense	distal	-3	no	8.458	9.098	EPSD	TCGA;ICGC;COSMIC	6.822	Up-regulation
Atypical_PIKK_FRAP_MTOR_ST	Q9UQ35	SRRM2	P42345	MTOR	S1824	R1827Q	1827	Missense	distal	3	no	8.458	7.192	EPSD	TCGA;COSMIC;GDSC;CCLE	6.822	Down-regulation
Atypical_PIKK_FRAP_MTOR_ST	Q9UQ35	SRRM2	P42345	MTOR	T1844	R1841H	1841	Missense	distal	-3	no	10.177	9.430	EPSD	TCGA;ICGC;COSMIC	6.822	Down-regulation
Atypical_PIKK_FRAP_MTOR_ST	Q9UQ35	SRRM2	P42345	MTOR	S1857	R1853C	1853	Missense	distal	-4	no	8.858	6.918	EPSD	TCGA;ICGC;COSMIC	6.822	Down-regulation
Atypical_PIKK_FRAP_MTOR_ST	Q9UQ35	SRRM2	P42345	MTOR	S1857	S1854P	1854	Missense	distal	-3	no	8.858	8.425	EPSD	TCGA;ICGC;COSMIC	6.822	Down-regulation
Atypical_PIKK_FRAP_MTOR_ST	Q9UQ35	SRRM2	P42345	MTOR	S1857	R1863H	1863	Missense	distal	6	no	8.858	9.174	EPSD	TCGA;ICGC	6.822	Up-regulation
Atypical_PIKK_FRAP_MTOR_ST	Q9UQ35	SRRM2	P42345	MTOR	S1857	S1852P	1852	Missense	distal	-5	no	8.858	8.906	EPSD	TCGA;ICGC;COSMIC	6.822	Up-regulation
Atypical_PIKK_FRAP_MTOR_ST	Q9UQ35	SRRM2	P42345	MTOR	S1857	P1860Q	1860	Missense	distal	3	no	8.858	7.326	EPSD	TCGA;ICGC;COSMIC	6.822	Down-regulation
Atypical_PIKK_FRAP_MTOR_ST	Q9UQ35	SRRM2	P42345	MTOR	S1869	T1872S	1872	Missense	distal	3	no	6.552	6.959	EPSD	TCGA	6.822	Gain
Atypical_PIKK_FRAP_MTOR_ST	Q9UQ35	SRRM2	P42345	MTOR	S1869	H1873D	1873	Missense	distal	4	no	6.552	7.313	EPSD	TCGA;ICGC;COSMIC	6.822	Gain
Atypical_PIKK_FRAP_MTOR_ST	Q9UQ35	SRRM2	P42345	MTOR	T1880	H1873D	1873	Missense	distal	-7	no	5.569	6.922	EPSD	TCGA;ICGC;COSMIC	6.822	Gain
Atypical_PIKK_FRAP_MTOR_ST	Q9UQ35	SRRM2	P42345	MTOR	S1893	R1899W	1899	Missense	distal	6	no	11.074	11.605	EPSD	TCGA;ICGC;COSMIC	6.822	Up-regulation
Atypical_PIKK_FRAP_MTOR_ST	Q9UQ35	SRRM2	P42345	MTOR	S1893	R1891Q	1891	Missense	proximal	-2	no	11.074	11.414	EPSD	TCGA;ICGC;COSMIC	6.822	Up-regulation
Atypical_PIKK_FRAP_MTOR_ST	Q9UQ35	SRRM2	P42345	MTOR	S1916	S1911F	1911	Missense	distal	-5	no	9.550	9.556	EPSD	TCGA;ICGC;COSMIC	6.822	Up-regulation
Atypical_PIKK_FRAP_MTOR_ST	Q9UQ35	SRRM2	P42345	MTOR	S1916	R1909Q	1909	Missense	distal	-7	no	9.550	9.472	EPSD	TCGA;ICGC;COSMIC	6.822	Down-regulation
Atypical_PIKK_FRAP_MTOR_ST	Q9UQ35	SRRM2	P42345	MTOR	T1927	R1934H	1934	Missense	distal	7	no	9.658	9.500	EPSD	TCGA;ICGC;COSMIC	6.822	Down-regulation
Atypical_PIKK_FRAP_MTOR_ST	Q9UQ35	SRRM2	P42345	MTOR	T1927	R1926T	1926	Missense	proximal	-1	no	9.658	9.765	EPSD	TCGA;ICGC;COSMIC	6.822	Up-regulation
Atypical_PIKK_FRAP_MTOR_ST	Q9UQ35	SRRM2	P42345	MTOR	T1939	R1943C	1943	Missense	distal	4	no	10.018	9.805	EPSD	TCGA;ICGC	6.822	Down-regulation
Atypical_PIKK_FRAP_MTOR_ST	Q9UQ35	SRRM2	P42345	MTOR	T1939	R1934H	1934	Missense	distal	-5	no	10.018	10.023	EPSD	TCGA;ICGC;COSMIC	6.822	Up-regulation
Atypical_PIKK_FRAP_MTOR_ST	Q9UQ35	SRRM2	P42345	MTOR	T1939	R1943L	1943	Missense	distal	4	no	10.018	9.951	EPSD	TCGA;ICGC;COSMIC	6.822	Down-regulation
Atypical_PIKK_FRAP_MTOR_ST	Q9UQ35	SRRM2	P42345	MTOR	T1939	S1935P	1935	Missense	distal	-4	no	10.018	9.889	EPSD	TCGA;ICGC;COSMIC	6.822	Down-regulation
Atypical_PIKK_FRAP_MTOR_ST	Q9UQ35	SRRM2	P42345	MTOR	T1950	R1943C	1943	Missense	distal	-7	no	11.438	10.343	EPSD	TCGA;ICGC	6.822	Down-regulation
Atypical_PIKK_FRAP_MTOR_ST	Q9UQ35	SRRM2	P42345	MTOR	T1950	R1943L	1943	Missense	distal	-7	no	11.438	11.627	EPSD	TCGA;ICGC;COSMIC	6.822	Up-regulation
Atypical_PIKK_FRAP_MTOR_ST	Q9UQ35	SRRM2	P42345	MTOR	T1950	R1955H	1955	Missense	distal	5	no	11.438	11.743	EPSD	TCGA;ICGC;COSMIC	6.822	Up-regulation
Atypical_PIKK_FRAP_MTOR_ST	Q9UQ35	SRRM2	P42345	MTOR	T1950	R1955C	1955	Missense	distal	5	no	11.438	11.222	EPSD	TCGA;ICGC;COSMIC	6.822	Down-regulation
Atypical_PIKK_FRAP_MTOR_ST	Q9UQ35	SRRM2	P42345	MTOR	T1962	S1958C	1958	Missense	distal	-4	no	7.123	5.298	EPSD	TCGA;ICGC;COSMIC	6.822	Loss
Atypical_PIKK_FRAP_MTOR_ST	Q9UQ35	SRRM2	P42345	MTOR	T1962	R1955H	1955	Missense	distal	-7	no	7.123	6.774	EPSD	TCGA;ICGC;COSMIC	6.822	Loss
Atypical_PIKK_FRAP_MTOR_ST	Q9UQ35	SRRM2	P42345	MTOR	T1962	R1955C	1955	Missense	distal	-7	no	7.123	6.028	EPSD	TCGA;ICGC;COSMIC	6.822	Loss
Atypical_PIKK_FRAP_MTOR_ST	Q9UQ35	SRRM2	P42345	MTOR	S1987	R1991Q	1991	Missense	distal	4	no	8.895	9.026	EPSD	TCGA;ICGC;COSMIC	6.822	Up-regulation
Atypical_PIKK_FRAP_MTOR_ST	Q9UQ35	SRRM2	P42345	MTOR	S1987	S1994C	1994	Missense	distal	7	no	8.895	10.117	EPSD	TCGA;ICGC;COSMIC	6.822	Up-regulation
Atypical_PIKK_FRAP_MTOR_ST	Q9UQ35	SRRM2	P42345	MTOR	S1987	V1989I	1989	Missense	proximal	2	no	8.895	8.863	EPSD	TCGA;ICGC;COSMIC	6.822	Down-regulation
Atypical_PIKK_FRAP_MTOR_ST	Q9UQ35	SRRM2	P42345	MTOR	S1987	S1987Y	1987	Missense	central	0	yes	8.895	0.000	EPSD	TCGA;ICGC	6.822	Loss
Atypical_PIKK_FRAP_MTOR_ST	Q9UQ35	SRRM2	P42345	MTOR	S1999	S1994C	1994	Missense	distal	-5	no	9.503	9.769	EPSD	TCGA;ICGC;COSMIC	6.822	Up-regulation
Atypical_PIKK_FRAP_MTOR_ST	Q9UQ35	SRRM2	P42345	MTOR	S2011	R2017H	2017	Missense	distal	6	no	9.536	9.852	EPSD	TCGA;ICGC;COSMIC	6.822	Up-regulation
Atypical_PIKK_FRAP_MTOR_ST	Q9UQ35	SRRM2	P42345	MTOR	S2011	R2016H	2016	Missense	distal	5	no	9.536	9.841	EPSD	TCGA;ICGC;COSMIC	6.822	Up-regulation
Atypical_PIKK_FRAP_MTOR_ST	Q9UQ35	SRRM2	P42345	MTOR	S2011	R2015C	2015	Missense	distal	4	no	9.536	9.323	EPSD	TCGA;ICGC;COSMIC	6.822	Down-regulation
Atypical_PIKK_FRAP_MTOR_ST	Q9UQ35	SRRM2	P42345	MTOR	T2022	R2017H	2017	Missense	distal	-5	no	8.270	8.274	EPSD	TCGA;ICGC;COSMIC	6.822	Up-regulation
Atypical_PIKK_FRAP_MTOR_ST	Q9UQ35	SRRM2	P42345	MTOR	T2022	R2029H	2029	Missense	distal	7	no	8.270	8.113	EPSD	TCGA;ICGC;COSMIC	6.822	Down-regulation
Atypical_PIKK_FRAP_MTOR_ST	Q9UQ35	SRRM2	P42345	MTOR	T2022	R2021Q	2021	Missense	proximal	-1	no	8.270	8.289	EPSD	TCGA;ICGC;COSMIC	6.822	Up-regulation
Atypical_PIKK_FRAP_MTOR_ST	Q9UQ35	SRRM2	P42345	MTOR	T2022	R2016H	2016	Missense	distal	-6	no	8.270	7.463	EPSD	TCGA;ICGC;COSMIC	6.822	Down-regulation
Atypical_PIKK_FRAP_MTOR_ST	Q9UQ35	SRRM2	P42345	MTOR	T2022	R2015C	2015	Missense	distal	-7	no	8.270	7.175	EPSD	TCGA;ICGC;COSMIC	6.822	Down-regulation
Atypical_PIKK_FRAP_MTOR_ST	Q9UQ35	SRRM2	P42345	MTOR	T2034	R2029H	2029	Missense	distal	-5	no	8.206	8.211	EPSD	TCGA;ICGC;COSMIC	6.822	Up-regulation
Atypical_PIKK_FRAP_MTOR_ST	Q9UQ35	SRRM2	P42345	MTOR	T2034	P2038S	2038	Missense	distal	4	no	8.206	8.462	EPSD	TCGA;ICGC;COSMIC	6.822	Up-regulation
Atypical_PIKK_FRAP_MTOR_ST	Q9UQ35	SRRM2	P42345	MTOR	S2046	I2050N	2050	Missense	distal	4	no	10.758	10.720	EPSD	TCGA	6.822	Down-regulation
Atypical_PIKK_FRAP_MTOR_ST	Q9UQ35	SRRM2	P42345	MTOR	S2046	R2043Q	2043	Missense	distal	-3	no	10.758	10.150	EPSD	TCGA;ICGC;CCLE	6.822	Down-regulation
Atypical_PIKK_FRAP_MTOR_ST	Q9UQ35	SRRM2	P42345	MTOR	T2058	R2055S	2055	Missense	distal	-3	no	11.832	11.486	EPSD	TCGA;ICGC;COSMIC	6.822	Down-regulation
Atypical_PIKK_FRAP_MTOR_ST	Q9UQ35	SRRM2	P42345	MTOR	T2058	R2057C	2057	Missense	proximal	-1	no	11.832	12.005	EPSD	TCGA;ICGC;COSMIC	6.822	Up-regulation
Atypical_PIKK_FRAP_MTOR_ST	Q9UQ35	SRRM2	P42345	MTOR	T2058	R2060Q	2060	Missense	proximal	2	no	11.832	11.820	EPSD	TCGA;ICGC;COSMIC	6.822	Down-regulation
Atypical_PIKK_FRAP_MTOR_ST	Q9UQ35	SRRM2	P42345	MTOR	T2092	R2097I	2097	Missense	distal	5	no	10.428	9.939	EPSD	TCGA;ICGC;COSMIC	6.822	Down-regulation
Atypical_PIKK_FRAP_MTOR_ST	Q9UQ35	SRRM2	P42345	MTOR	T2092	P2093S	2093	Missense	proximal	1	no	10.428	1.904	EPSD	TCGA;ICGC;COSMIC	6.822	Loss
Atypical_PIKK_FRAP_MTOR_ST	Q9UQ35	SRRM2	P42345	MTOR	T2092	H2099Y	2099	Missense	distal	7	no	10.428	9.394	EPSD	TCGA;ICGC;COSMIC	6.822	Down-regulation
Atypical_PIKK_FRAP_MTOR_ST	Q9UQ35	SRRM2	P42345	MTOR	T2092	H2099N	2099	Missense	distal	7	no	10.428	10.391	EPSD	TCGA;ICGC;COSMIC	6.822	Down-regulation
Atypical_PIKK_FRAP_MTOR_ST	Q9UQ35	SRRM2	P42345	MTOR	T2092	R2087H	2087	Missense	distal	-5	no	10.428	10.432	EPSD	TCGA;ICGC;COSMIC	6.822	Up-regulation
Atypical_PIKK_FRAP_MTOR_ST	Q9UQ35	SRRM2	P42345	MTOR	S2132	R2129C	2129	Missense	distal	-3	no	7.288	6.576	EPSD	TCGA;ICGC;COSMIC;GDSC	6.822	Loss
Atypical_PIKK_FRAP_MTOR_ST	Q9UQ35	SRRM2	P42345	MTOR	S2132	P2126L	2126	Missense	distal	-6	no	7.288	6.513	EPSD	TCGA;ICGC	6.822	Loss
Atypical_PIKK_FRAP_MTOR_ST	Q9UQ35	SRRM2	P42345	MTOR	S2171	H2176Y	2176	Missense	distal	5	no	8.742	8.309	EPSD	TCGA;ICGC;COSMIC	6.822	Down-regulation
Atypical_PIKK_FRAP_MTOR_ST	Q9UQ35	SRRM2	P42345	MTOR	T2261	A2265S	2265	Missense	distal	4	no	7.929	8.403	EPSD	TCGA;ICGC;COSMIC	6.822	Up-regulation
Atypical_PIKK_FRAP_MTOR_ST	Q9UQ35	SRRM2	P42345	MTOR	S2272	A2265S	2265	Missense	distal	-7	no	8.642	9.482	EPSD	TCGA;ICGC;COSMIC	6.822	Up-regulation
Atypical_PIKK_FRAP_MTOR_ST	Q9UQ35	SRRM2	P42345	MTOR	S2272	R2274K	2274	Missense	proximal	2	no	8.642	10.287	EPSD	TCGA;ICGC;COSMIC	6.822	Up-regulation
Atypical_PIKK_FRAP_MTOR_ST	Q9UQ35	SRRM2	P42345	MTOR	S2272	A2276V	2276	Missense	distal	4	no	8.642	8.804	EPSD	TCGA;ICGC;COSMIC	6.822	Up-regulation
Atypical_PIKK_FRAP_MTOR_ST	Q9UQ35	SRRM2	P42345	MTOR	T2289	P2290L	2290	Missense	proximal	1	no	8.413	2.444	EPSD	TCGA;ICGC	6.822	Loss
Atypical_PIKK_FRAP_MTOR_ST	Q9UQ35	SRRM2	P42345	MTOR	T2316	P2318S	2318	Missense	proximal	2	no	9.459	8.964	EPSD	TCGA;ICGC;COSMIC	6.822	Down-regulation
Atypical_PIKK_FRAP_MTOR_ST	Q9UQ35	SRRM2	P42345	MTOR	T2316	L2311V	2311	Missense	distal	-5	no	9.459	9.420	EPSD	TCGA;ICGC;COSMIC	6.822	Down-regulation
Atypical_PIKK_FRAP_MTOR_ST	Q9UQ35	SRRM2	P42345	MTOR	T2329	S2335C	2335	Missense	distal	6	no	7.653	5.958	EPSD	TCGA;ICGC;COSMIC	6.822	Loss
Atypical_PIKK_FRAP_MTOR_ST	Q9UQ35	SRRM2	P42345	MTOR	T2329	P2324L	2324	Missense	distal	-5	no	7.653	7.581	EPSD	TCGA;ICGC;COSMIC	6.822	Down-regulation
Atypical_PIKK_FRAP_MTOR_ST	Q9UQ35	SRRM2	P42345	MTOR	T2329	P2324S	2324	Missense	distal	-5	no	7.653	7.605	EPSD	TCGA;ICGC;COSMIC;GDSC	6.822	Down-regulation
Atypical_PIKK_FRAP_MTOR_ST	Q9UQ35	SRRM2	P42345	MTOR	S2382	T2381S	2381	Missense	proximal	-1	no	7.948	8.002	EPSD	TCGA;ICGC;COSMIC	6.822	Up-regulation
Atypical_PIKK_FRAP_MTOR_ST	Q9UQ35	SRRM2	P42345	MTOR	S2382	A2389T	2389	Missense	distal	7	no	7.948	7.428	EPSD	TCGA;ICGC	6.822	Down-regulation
Atypical_PIKK_FRAP_MTOR_ST	Q9UQ35	SRRM2	P42345	MTOR	S2398	G2395C	2395	Missense	distal	-3	no	9.346	8.608	EPSD	TCGA;ICGC;COSMIC	6.822	Down-regulation
Atypical_PIKK_FRAP_MTOR_ST	Q9UQ35	SRRM2	P42345	MTOR	S2398	R2404Q	2404	Missense	distal	6	no	9.346	9.730	EPSD	TCGA;ICGC;COSMIC	6.822	Up-regulation
Atypical_PIKK_FRAP_MTOR_ST	Q9UQ35	SRRM2	P42345	MTOR	S2412	A2413P	2413	Missense	proximal	1	no	-1.021	7.862	EPSD	TCGA;ICGC;COSMIC	6.822	Gain
Atypical_PIKK_FRAP_MTOR_ST	Q9UQ35	SRRM2	P42345	MTOR	S2426	R2423Q	2423	Missense	distal	-3	no	9.327	8.718	EPSD	TCGA;ICGC;COSMIC;CCLE	6.822	Down-regulation
Atypical_PIKK_FRAP_MTOR_ST	Q9UQ35	SRRM2	P42345	MTOR	S2532	S2533Y	2533	Missense	proximal	1	no	3.373	7.067	EPSD	TCGA;ICGC;COSMIC	6.822	Gain
Atypical_PIKK_FRAP_MTOR_ST	Q9UQ35	SRRM2	P42345	MTOR	S2537	S2538P	2538	Missense	proximal	1	no	2.910	11.434	EPSD	TCGA;ICGC;COSMIC	6.822	Gain
Atypical_PIKK_FRAP_MTOR_ST	Q9UQ35	SRRM2	P42345	MTOR	S2545	S2544F	2544	Missense	proximal	-1	no	7.702	7.519	EPSD	TCGA;ICGC;COSMIC;GDSC	6.822	Down-regulation
Atypical_PIKK_FRAP_MTOR_ST	Q9UQ35	SRRM2	P42345	MTOR	S2545	S2538P	2538	Missense	distal	-7	no	7.702	7.265	EPSD	TCGA;ICGC;COSMIC	6.822	Down-regulation
Atypical_PIKK_FRAP_MTOR_ST	Q9UQ35	SRRM2	P42345	MTOR	S2581	K2587N	2587	Missense	distal	6	no	10.090	9.592	EPSD	TCGA;ICGC	6.822	Down-regulation
Atypical_PIKK_FRAP_MTOR_ST	Q9UQ35	SRRM2	P42345	MTOR	T2583	K2587N	2587	Missense	distal	4	no	8.259	8.055	EPSD	TCGA;ICGC	6.822	Down-regulation
Atypical_PIKK_FRAP_MTOR_ST	Q9UQ35	SRRM2	P42345	MTOR	S2650	S2644T	2644	Missense	distal	-6	no	10.432	10.374	EPSD	TCGA;ICGC;COSMIC	6.822	Down-regulation
Atypical_PIKK_FRAP_MTOR_ST	Q9UQ35	SRRM2	P42345	MTOR	S2650	G2655V	2655	Missense	distal	5	no	10.432	10.892	EPSD	TCGA;ICGC;COSMIC	6.822	Up-regulation
Atypical_PIKK_FRAP_MTOR_ST	Q9UQ35	SRRM2	P42345	MTOR	S2650	S2645L	2645	Missense	distal	-5	no	10.432	10.409	EPSD	TCGA;ICGC	6.822	Down-regulation
Atypical_PIKK_FRAP_MTOR_ST	Q9UQ35	SRRM2	P42345	MTOR	S2650	K2653R	2653	Missense	distal	3	no	10.432	11.531	EPSD	TCGA;ICGC;COSMIC	6.822	Up-regulation
Atypical_PIKK_FRAP_MTOR_ST	Q9UQ35	SRRM2	P42345	MTOR	S2664	P2665H	2665	Missense	proximal	1	no	10.313	-16.878	EPSD	TCGA;ICGC;COSMIC	6.822	Loss
Atypical_PIKK_FRAP_MTOR_ST	Q9UQ35	SRRM2	P42345	MTOR	S2702	S2706L	2706	Missense	distal	4	no	7.488	6.848	EPSD	TCGA;ICGC;COSMIC	6.822	Down-regulation
Atypical_PIKK_FRAP_MTOR_ST	Q9UQ35	SRRM2	P42345	MTOR	S2702	R2708Q	2708	Missense	distal	6	no	7.488	7.872	EPSD	TCGA;ICGC	6.822	Up-regulation
Atypical_PIKK_FRAP_MTOR_ST	Q9UQ35	SRRM2	P42345	MTOR	S2706	S2706L	2706	Missense	central	0	yes	7.986	0.000	EPSD	TCGA;ICGC;COSMIC	6.822	Loss
Atypical_PIKK_FRAP_MTOR_ST	Q9UQ35	SRRM2	P42345	MTOR	S2706	R2708Q	2708	Missense	proximal	2	no	7.986	7.974	EPSD	TCGA;ICGC	6.822	Down-regulation
Atypical_PIKK_FRAP_MTOR_ST	Q9UQ35	SRRM2	P42345	MTOR	S2706	S2712I	2712	Missense	distal	6	no	7.986	7.122	EPSD	TCGA;ICGC;COSMIC	6.822	Down-regulation
Atypical_PIKK_FRAP_MTOR_ST	Q9UQ35	SRRM2	P42345	MTOR	S2712	S2706L	2706	Missense	distal	-6	no	7.479	6.725	EPSD	TCGA;ICGC;COSMIC	6.822	Loss
Atypical_PIKK_FRAP_MTOR_ST	Q9UQ35	SRRM2	P42345	MTOR	S2712	R2708Q	2708	Missense	distal	-4	no	7.479	6.982	EPSD	TCGA;ICGC	6.822	Down-regulation
Atypical_PIKK_FRAP_MTOR_ST	Q9UQ35	SRRM2	P42345	MTOR	S2712	S2712I	2712	Missense	central	0	yes	7.479	0.000	EPSD	TCGA;ICGC;COSMIC	6.822	Loss
Atypical_PIKK_FRAP_MTOR_ST	P42345	MTOR	P42345	MTOR	T314	R311H	311	Missense	distal	-3	no	9.077	8.330	EPSD	TCGA;ICGC;COSMIC	6.822	Down-regulation
Atypical_PIKK_FRAP_MTOR_ST	P42345	MTOR	P42345	MTOR	T314	R311C	311	Missense	distal	-3	no	9.077	8.365	EPSD	TCGA;ICGC;COSMIC	6.822	Down-regulation
Atypical_PIKK_FRAP_MTOR_ST	P42345	MTOR	P42345	MTOR	S567	L570F	570	Missense	distal	3	no	4.549	7.222	EPSD	TCGA;ICGC;COSMIC	6.822	Gain
Atypical_PIKK_FRAP_MTOR_ST	P42345	MTOR	P42345	MTOR	T572	L570F	570	Missense	proximal	-2	no	6.580	6.893	EPSD	TCGA;ICGC;COSMIC	6.822	Gain
Atypical_PIKK_FRAP_MTOR_ST	P42345	MTOR	P42345	MTOR	S720	R717Q	717	Missense	distal	-3	no	7.913	7.304	EPSD	TCGA;ICGC;COSMIC	6.822	Down-regulation
Atypical_PIKK_FRAP_MTOR_ST	P42345	MTOR	P42345	MTOR	S720	N722D	722	Missense	proximal	2	no	7.913	9.171	EPSD	TCGA;ICGC;COSMIC	6.822	Up-regulation
Atypical_PIKK_FRAP_MTOR_ST	P42345	MTOR	P42345	MTOR	S1843	E1845K	1845	Missense	proximal	2	no	7.462	6.557	EPSD	TCGA;ICGC;COSMIC	6.822	Loss
Atypical_PIKK_FRAP_MTOR_ST	P42345	MTOR	P42345	MTOR	S1843	T1837A	1837	Missense	distal	-6	no	7.462	7.183	EPSD	TCGA;ICGC;COSMIC	6.822	Down-regulation
Atypical_PIKK_FRAP_MTOR_ST	P42345	MTOR	P42345	MTOR	S1843	T1841A	1841	Missense	proximal	-2	no	7.462	7.959	EPSD	TCGA;ICGC;COSMIC	6.822	Up-regulation
Atypical_PIKK_FRAP_MTOR_ST	P42345	MTOR	P42345	MTOR	T1861	Q1866H	1866	Missense	distal	5	no	6.635	7.748	EPSD	TCGA;ICGC;COSMIC	6.822	Gain
Atypical_PIKK_FRAP_MTOR_ST	P42345	MTOR	P42345	MTOR	T1948	V1953L	1953	Missense	distal	5	no	10.116	10.481	EPSD	TCGA;ICGC;COSMIC	6.822	Up-regulation
Atypical_PIKK_FRAP_MTOR_ST	P42345	MTOR	P42345	MTOR	T1948	T1948M	1948	Missense	central	0	yes	10.116	0.000	EPSD	TCGA;ICGC;COSMIC;GDSC;CCLE	6.822	Loss
Atypical_PIKK_FRAP_MTOR_ST	P42345	MTOR	P42345	MTOR	S1982	S1980C	1980	Missense	proximal	-2	no	6.733	6.882	EPSD	TCGA;ICGC;COSMIC	6.822	Gain
Atypical_PIKK_FRAP_MTOR_ST	P42345	MTOR	P42345	MTOR	S1982	T1977R	1977	Missense	distal	-5	no	6.733	6.868	EPSD	TCGA;ICGC;COSMIC	6.822	Gain
Atypical_PIKK_FRAP_MTOR_ST	P42345	MTOR	P42345	MTOR	S2221	S2215Y	2215	Missense	distal	-6	no	8.517	7.647	EPSD	TCGA;ICGC;COSMIC;CCLE	6.822	Down-regulation
Atypical_PIKK_FRAP_MTOR_ST	P42345	MTOR	P42345	MTOR	S2221	S2215F	2215	Missense	distal	-6	no	8.517	8.042	EPSD	TCGA;ICGC;COSMIC;GDSC;CCLE	6.822	Down-regulation
Atypical_PIKK_FRAP_MTOR_ST	P42345	MTOR	P42345	MTOR	S2221	Q2223K	2223	Missense	proximal	2	no	8.517	10.175	EPSD	TCGA;ICGC;COSMIC	6.822	Up-regulation
Atypical_PIKK_FRAP_MTOR_ST	P42345	MTOR	P42345	MTOR	S2221	I2228T	2228	Missense	distal	7	no	8.517	7.197	EPSD	TCGA;ICGC;COSMIC	6.822	Down-regulation
Atypical_PIKK_FRAP_MTOR_ST	P42345	MTOR	P42345	MTOR	S2221	L2216P	2216	Missense	distal	-5	no	8.517	8.589	EPSD	TCGA;ICGC;COSMIC	6.822	Up-regulation
Atypical_PIKK_FRAP_MTOR_ST	P42345	MTOR	P42345	MTOR	S2221	Y2225C	2225	Missense	distal	4	no	8.517	8.410	EPSD	TCGA;ICGC;COSMIC	6.822	Down-regulation
Atypical_PIKK_FRAP_MTOR_ST	P42345	MTOR	P42345	MTOR	S2448	R2441Q	2441	Missense	distal	-7	no	6.949	6.871	EPSD	TCGA;ICGC;COSMIC	6.822	Down-regulation
Atypical_PIKK_FRAP_MTOR_ST	P42345	MTOR	P42345	MTOR	T2474	T2471M	2471	Missense	distal	-3	no	7.756	7.343	EPSD;PhosphoSitePlus	TCGA;COSMIC;GDSC;CCLE	6.822	Down-regulation
Atypical_PIKK_FRAP_MTOR_ST	P42345	MTOR	P42345	MTOR	S2478	T2471M	2471	Missense	distal	-7	no	7.854	7.215	EPSD;PhosphoSitePlus	TCGA;COSMIC;GDSC;CCLE	6.822	Down-regulation
Atypical_PIKK_FRAP_MTOR_ST	P42345	MTOR	P42345	MTOR	S2481	V2488G	2488	Missense	distal	7	no	8.388	8.259	EPSD;PhosphoSitePlus	TCGA	6.822	Down-regulation
Atypical_PIKK_FRAP_MTOR_ST	P55199	ELL	P42345	MTOR	T180	A187D	187	Missense	distal	7	no	5.914	6.901	EPSD	TCGA;COSMIC	6.822	Gain
Atypical_PIKK_FRAP_MTOR_ST	P55199	ELL	P42345	MTOR	T180	A187V	187	Missense	distal	7	no	5.914	6.852	EPSD	TCGA;COSMIC	6.822	Gain
Atypical_PIKK_FRAP_MTOR_ST	P55199	ELL	P42345	MTOR	S309	R314C	314	Missense	distal	5	no	16.235	16.020	PhosphoSitePlus	TCGA	6.822	Down-regulation
Atypical_PIKK_FRAP_MTOR_ST	P55199	ELL	P42345	MTOR	S309	A307D	307	Missense	proximal	-2	no	16.235	15.350	PhosphoSitePlus	TCGA;COSMIC	6.822	Down-regulation
Atypical_PIKK_FRAP_MTOR_ST	P55199	ELL	P42345	MTOR	S319	R314C	314	Missense	distal	-5	no	7.877	8.001	EPSD	TCGA	6.822	Up-regulation
Atypical_PIKK_FRAP_MTOR_ST	P55199	ELL	P42345	MTOR	S442	R445H	445	Missense	distal	3	no	8.058	8.228	EPSD	TCGA;COSMIC;GDSC;CCLE	6.822	Up-regulation
Atypical_PIKK_FRAP_MTOR_ST	O75385	ULK1	P42345	MTOR	S281	P282H	282	Missense	proximal	1	no	12.562	-14.629	EPSD	TCGA;ICGC;COSMIC	6.822	Loss
Atypical_PIKK_FRAP_MTOR_ST	O75385	ULK1	P42345	MTOR	S281	D279N	279	Missense	proximal	-2	no	12.562	12.295	EPSD	TCGA;ICGC;COSMIC	6.822	Down-regulation
Atypical_PIKK_FRAP_MTOR_ST	O75385	ULK1	P42345	MTOR	S287	P282H	282	Missense	distal	-5	no	8.168	8.266	EPSD	TCGA;ICGC;COSMIC	6.822	Up-regulation
Atypical_PIKK_FRAP_MTOR_ST	O75385	ULK1	P42345	MTOR	S287	S294L	294	Missense	distal	7	no	8.168	9.146	EPSD	TCGA;ICGC;COSMIC	6.822	Up-regulation
Atypical_PIKK_FRAP_MTOR_ST	O75385	ULK1	P42345	MTOR	S287	P291R	291	Missense	distal	4	no	8.168	7.851	EPSD	TCGA;ICGC;COSMIC	6.822	Down-regulation
Atypical_PIKK_FRAP_MTOR_ST	O75385	ULK1	P42345	MTOR	S307	S310F	310	Missense	distal	3	no	7.409	7.814	EPSD	TCGA;ICGC;COSMIC	6.822	Up-regulation
Atypical_PIKK_FRAP_MTOR_ST	O75385	ULK1	P42345	MTOR	S307	L312P	312	Missense	distal	5	no	7.409	6.036	EPSD	TCGA;ICGC;COSMIC	6.822	Loss
Atypical_PIKK_FRAP_MTOR_ST	O75385	ULK1	P42345	MTOR	S307	S305N	305	Missense	proximal	-2	no	7.409	6.818	EPSD	TCGA;ICGC;COSMIC	6.822	Loss
Atypical_PIKK_FRAP_MTOR_ST	O75385	ULK1	P42345	MTOR	S314	S310F	310	Missense	distal	-4	no	10.170	10.194	EPSD	TCGA;ICGC;COSMIC	6.822	Up-regulation
Atypical_PIKK_FRAP_MTOR_ST	O75385	ULK1	P42345	MTOR	S314	S317F	317	Missense	distal	3	no	10.170	10.574	EPSD	TCGA;ICGC;COSMIC;GDSC	6.822	Up-regulation
Atypical_PIKK_FRAP_MTOR_ST	O75385	ULK1	P42345	MTOR	S314	L312P	312	Missense	proximal	-2	no	10.170	10.660	EPSD	TCGA;ICGC;COSMIC	6.822	Up-regulation
Atypical_PIKK_FRAP_MTOR_ST	O75385	ULK1	P42345	MTOR	S314	E320K	320	Missense	distal	6	no	10.170	9.265	EPSD	TCGA;ICGC;COSMIC;GDSC	6.822	Down-regulation
Atypical_PIKK_FRAP_MTOR_ST	O75385	ULK1	P42345	MTOR	S330	D333H	333	Missense	distal	3	no	6.752	7.317	EPSD	TCGA;ICGC;COSMIC	6.822	Gain
Atypical_PIKK_FRAP_MTOR_ST	O75385	ULK1	P42345	MTOR	S405	S403F	403	Missense	proximal	-2	no	7.192	7.371	EPSD	TCGA;ICGC;COSMIC	6.822	Up-regulation
Atypical_PIKK_FRAP_MTOR_ST	O75385	ULK1	P42345	MTOR	S409	S403F	403	Missense	distal	-6	no	6.979	6.504	EPSD	TCGA;ICGC;COSMIC	6.822	Loss
Atypical_PIKK_FRAP_MTOR_ST	O75385	ULK1	P42345	MTOR	S409	P414S	414	Missense	distal	5	no	6.979	6.866	EPSD	TCGA;ICGC;COSMIC	6.822	Down-regulation
Atypical_PIKK_FRAP_MTOR_ST	O75385	ULK1	P42345	MTOR	S410	S403F	403	Missense	distal	-7	no	7.123	6.898	EPSD	TCGA;ICGC;COSMIC	6.822	Down-regulation
Atypical_PIKK_FRAP_MTOR_ST	O75385	ULK1	P42345	MTOR	S410	P414S	414	Missense	distal	4	no	7.123	7.378	EPSD	TCGA;ICGC;COSMIC	6.822	Up-regulation
Atypical_PIKK_FRAP_MTOR_ST	O75385	ULK1	P42345	MTOR	S410	R417W	417	Missense	distal	7	no	7.123	6.737	EPSD	TCGA;ICGC;COSMIC	6.822	Loss
Atypical_PIKK_FRAP_MTOR_ST	O75385	ULK1	P42345	MTOR	S411	P414S	414	Missense	distal	3	no	9.285	9.300	EPSD	TCGA;ICGC;COSMIC	6.822	Up-regulation
Atypical_PIKK_FRAP_MTOR_ST	O75385	ULK1	P42345	MTOR	S411	R417W	417	Missense	distal	6	no	9.285	9.816	EPSD	TCGA;ICGC;COSMIC	6.822	Up-regulation
Atypical_PIKK_FRAP_MTOR_ST	O75385	ULK1	P42345	MTOR	S413	P414S	414	Missense	proximal	1	no	12.999	4.475	EPSD	TCGA;ICGC;COSMIC	6.822	Loss
Atypical_PIKK_FRAP_MTOR_ST	O75385	ULK1	P42345	MTOR	S413	R417W	417	Missense	distal	4	no	12.999	13.161	EPSD	TCGA;ICGC;COSMIC	6.822	Up-regulation
Atypical_PIKK_FRAP_MTOR_ST	O75385	ULK1	P42345	MTOR	S450	L448M	448	Missense	proximal	-2	no	8.493	8.104	EPSD	TCGA;ICGC	6.822	Down-regulation
Atypical_PIKK_FRAP_MTOR_ST	O75385	ULK1	P42345	MTOR	S450	R443H	443	Missense	distal	-7	no	8.493	8.144	EPSD	TCGA;ICGC	6.822	Down-regulation
Atypical_PIKK_FRAP_MTOR_ST	O75385	ULK1	P42345	MTOR	S469	G466C	466	Missense	distal	-3	no	8.499	7.762	EPSD	TCGA;ICGC;COSMIC	6.822	Down-regulation
Atypical_PIKK_FRAP_MTOR_ST	O75385	ULK1	P42345	MTOR	S477	S479L	479	Missense	proximal	2	no	12.126	11.931	EPSD	TCGA;ICGC;COSMIC	6.822	Down-regulation
Atypical_PIKK_FRAP_MTOR_ST	O75385	ULK1	P42345	MTOR	S479	S479L	479	Missense	central	0	yes	10.447	0.000	EPSD	TCGA;ICGC;COSMIC	6.822	Loss
Atypical_PIKK_FRAP_MTOR_ST	O75385	ULK1	P42345	MTOR	T503	Q507E	507	Missense	distal	4	no	8.319	8.528	EPSD	TCGA;ICGC;COSMIC	6.822	Up-regulation
Atypical_PIKK_FRAP_MTOR_ST	O75385	ULK1	P42345	MTOR	T503	R500W	500	Missense	distal	-3	no	8.319	8.103	EPSD	TCGA;ICGC;COSMIC	6.822	Down-regulation
Atypical_PIKK_FRAP_MTOR_ST	O75385	ULK1	P42345	MTOR	S505	Q507E	507	Missense	proximal	2	no	5.594	8.157	EPSD	TCGA;ICGC;COSMIC	6.822	Gain
Atypical_PIKK_FRAP_MTOR_ST	O75385	ULK1	P42345	MTOR	T510	Q507E	507	Missense	distal	-3	no	8.039	7.927	EPSD	TCGA;ICGC;COSMIC	6.822	Down-regulation
Atypical_PIKK_FRAP_MTOR_ST	O75385	ULK1	P42345	MTOR	S522	R529L	529	Missense	distal	7	no	12.786	12.970	EPSD	TCGA;ICGC;COSMIC	6.822	Up-regulation
Atypical_PIKK_FRAP_MTOR_ST	O75385	ULK1	P42345	MTOR	S544	S544C	544	Missense	central	0	yes	7.935	0.000	EPSD	TCGA;ICGC;COSMIC	6.822	Loss
Atypical_PIKK_FRAP_MTOR_ST	O75385	ULK1	P42345	MTOR	S544	G549R	549	Missense	distal	5	no	7.935	8.265	EPSD	TCGA;ICGC;COSMIC	6.822	Up-regulation
Atypical_PIKK_FRAP_MTOR_ST	O75385	ULK1	P42345	MTOR	S544	R546C	546	Missense	proximal	2	no	7.935	8.101	EPSD	TCGA;ICGC;COSMIC	6.822	Up-regulation
Atypical_PIKK_FRAP_MTOR_ST	O75385	ULK1	P42345	MTOR	S544	R546H	546	Missense	proximal	2	no	7.935	7.557	EPSD	TCGA;ICGC	6.822	Down-regulation
Atypical_PIKK_FRAP_MTOR_ST	O75385	ULK1	P42345	MTOR	S623	S623F	623	Missense	central	0	yes	10.840	0.000	EPSD	TCGA;ICGC;COSMIC	6.822	Loss
Atypical_PIKK_FRAP_MTOR_ST	O75385	ULK1	P42345	MTOR	S623	P629L	629	Missense	distal	6	no	10.840	9.680	EPSD	TCGA;ICGC;COSMIC	6.822	Down-regulation
Atypical_PIKK_FRAP_MTOR_ST	O75385	ULK1	P42345	MTOR	S623	S630F	630	Missense	distal	7	no	10.840	11.420	EPSD	TCGA;ICGC;COSMIC	6.822	Up-regulation
Atypical_PIKK_FRAP_MTOR_ST	O75385	ULK1	P42345	MTOR	T636	P637T	637	Missense	proximal	1	no	14.602	8.330	EPSD	TCGA;ICGC;COSMIC	6.822	Down-regulation
Atypical_PIKK_FRAP_MTOR_ST	O75385	ULK1	P42345	MTOR	T636	T636A	636	Missense	central	0	yes	14.602	0.000	EPSD	TCGA;ICGC;COSMIC	6.822	Loss
Atypical_PIKK_FRAP_MTOR_ST	O75385	ULK1	P42345	MTOR	T636	P629L	629	Missense	distal	-7	no	14.602	14.469	EPSD	TCGA;ICGC;COSMIC	6.822	Down-regulation
Atypical_PIKK_FRAP_MTOR_ST	O75385	ULK1	P42345	MTOR	T636	S630F	630	Missense	distal	-6	no	14.602	14.127	EPSD	TCGA;ICGC;COSMIC	6.822	Down-regulation
Atypical_PIKK_FRAP_MTOR_ST	O75385	ULK1	P42345	MTOR	T636	P637S	637	Missense	proximal	1	no	14.602	6.078	EPSD	TCGA;ICGC;COSMIC	6.822	Loss
Atypical_PIKK_FRAP_MTOR_ST	O75385	ULK1	P42345	MTOR	S638	P637T	637	Missense	proximal	-1	no	7.101	7.115	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	6.822	Up-regulation
Atypical_PIKK_FRAP_MTOR_ST	O75385	ULK1	P42345	MTOR	S638	T636A	636	Missense	proximal	-2	no	7.101	7.598	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	6.822	Up-regulation
Atypical_PIKK_FRAP_MTOR_ST	O75385	ULK1	P42345	MTOR	S638	A644V	644	Missense	distal	6	no	7.101	7.793	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	6.822	Up-regulation
Atypical_PIKK_FRAP_MTOR_ST	O75385	ULK1	P42345	MTOR	S638	P637S	637	Missense	proximal	-1	no	7.101	7.169	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	6.822	Up-regulation
Atypical_PIKK_FRAP_MTOR_ST	O75385	ULK1	P42345	MTOR	T654	V651M	651	Missense	distal	-3	no	9.678	8.689	EPSD	TCGA;ICGC;COSMIC	6.822	Down-regulation
Atypical_PIKK_FRAP_MTOR_ST	O75385	ULK1	P42345	MTOR	T654	R648L	648	Missense	distal	-6	no	9.678	8.816	EPSD	TCGA;ICGC;COSMIC	6.822	Down-regulation
Atypical_PIKK_FRAP_MTOR_ST	O75385	ULK1	P42345	MTOR	T654	R657Q	657	Missense	distal	3	no	9.678	8.412	EPSD	TCGA;ICGC;COSMIC	6.822	Down-regulation
Atypical_PIKK_FRAP_MTOR_ST	O75385	ULK1	P42345	MTOR	T654	R648Q	648	Missense	distal	-6	no	9.678	9.414	EPSD	TCGA;ICGC	6.822	Down-regulation
Atypical_PIKK_FRAP_MTOR_ST	O75385	ULK1	P42345	MTOR	S696	R697L	697	Missense	proximal	1	no	4.137	8.001	EPSD	TCGA;ICGC;COSMIC	6.822	Gain
Atypical_PIKK_FRAP_MTOR_ST	O75385	ULK1	P42345	MTOR	S748	T755I	755	Missense	distal	7	no	14.773	16.093	EPSD	TCGA;ICGC;COSMIC	6.822	Up-regulation
Atypical_PIKK_FRAP_MTOR_ST	O75385	ULK1	P42345	MTOR	S748	R742H	742	Missense	distal	-6	no	14.773	13.966	EPSD	TCGA;ICGC;COSMIC	6.822	Down-regulation
Atypical_PIKK_FRAP_MTOR_ST	O75385	ULK1	P42345	MTOR	S750	T755I	755	Missense	distal	5	no	9.069	9.969	EPSD	TCGA;ICGC;COSMIC	6.822	Up-regulation
Atypical_PIKK_FRAP_MTOR_ST	O75385	ULK1	P42345	MTOR	S758	T755I	755	Missense	distal	-3	no	11.865	12.740	PhosphoSitePlus;EPSD	TCGA;ICGC;COSMIC	6.822	Up-regulation
Atypical_PIKK_FRAP_MTOR_ST	O75385	ULK1	P42345	MTOR	S973	R970H	970	Missense	distal	-3	no	8.221	7.474	EPSD	TCGA;COSMIC	6.822	Down-regulation
Atypical_PIKK_FRAP_MTOR_ST	Q9H8M2	BRD9	P42345	MTOR	S485	V486I	486	Missense	proximal	1	no	6.204	7.867	EPSD	TCGA;ICGC;COSMIC	6.822	Gain
Atypical_PIKK_FRAP_MTOR_ST	Q9H8M2	BRD9	P42345	MTOR	S552	R545W	545	Missense	distal	-7	no	6.559	7.020	EPSD	TCGA;COSMIC;CCLE	6.822	Gain
Atypical_PIKK_FRAP_MTOR_ST	Q9H8M2	BRD9	P42345	MTOR	S571	R569C	569	Missense	proximal	-2	no	6.956	7.234	EPSD	TCGA;ICGC;COSMIC	6.822	Up-regulation
Atypical_PIKK_FRAP_MTOR_ST	Q9H8M2	BRD9	P42345	MTOR	S571	S566N	566	Missense	distal	-5	no	6.956	6.867	EPSD	TCGA;ICGC	6.822	Down-regulation
Atypical_PIKK_FRAP_MTOR_ST	Q9H8M2	BRD9	P42345	MTOR	S588	P591S	591	Missense	distal	3	no	19.616	19.630	PhosphoSitePlus	TCGA;ICGC;COSMIC	6.822	Up-regulation
Atypical_PIKK_FRAP_MTOR_ST	Q9H8M2	BRD9	P42345	MTOR	S594	K596N	596	Missense	proximal	2	no	9.543	8.208	EPSD	TCGA;ICGC;COSMIC	6.822	Down-regulation
Atypical_PIKK_FRAP_MTOR_ST	Q9H8M2	BRD9	P42345	MTOR	S594	P591S	591	Missense	distal	-3	no	9.543	9.975	EPSD	TCGA;ICGC;COSMIC	6.822	Up-regulation
Atypical_PIKK_FRAP_MTOR_ST	Q9H8M2	BRD9	P42345	MTOR	T597	K596N	596	Missense	proximal	-1	no	7.148	7.087	EPSD	TCGA;ICGC;COSMIC	6.822	Down-regulation
Atypical_PIKK_FRAP_MTOR_ST	Q9H8M2	BRD9	P42345	MTOR	T597	P591S	591	Missense	distal	-6	no	7.148	7.128	EPSD	TCGA;ICGC;COSMIC	6.822	Down-regulation
Atypical_PIKK_FRAP_MTOR_ST	Q8TB45	DEPTOR	P42345	MTOR	S244	R249S	249	Missense	distal	5	no	10.341	9.349	EPSD	TCGA;COSMIC	6.822	Down-regulation
Atypical_PIKK_FRAP_MTOR_ST	Q8TB45	DEPTOR	P42345	MTOR	S244	S244N	244	Missense	central	0	yes	10.341	0.000	EPSD	TCGA;COSMIC	6.822	Loss
Atypical_PIKK_FRAP_MTOR_ST	Q8TB45	DEPTOR	P42345	MTOR	S260	M262I	262	Missense	proximal	2	no	7.170	8.557	EPSD	TCGA;COSMIC	6.822	Up-regulation
Atypical_PIKK_FRAP_MTOR_ST	Q8TB45	DEPTOR	P42345	MTOR	S260	V264L	264	Missense	distal	4	no	7.170	6.843	EPSD	TCGA;COSMIC	6.822	Down-regulation
Atypical_PIKK_FRAP_MTOR_ST	Q8TB45	DEPTOR	P42345	MTOR	S260	S265N	265	Missense	distal	5	no	7.170	8.652	EPSD	TCGA;COSMIC	6.822	Up-regulation
Atypical_PIKK_FRAP_MTOR_ST	Q8TB45	DEPTOR	P42345	MTOR	S265	M262I	262	Missense	distal	-3	no	12.264	13.552	EPSD;PhosphoSitePlus	TCGA;COSMIC	6.822	Up-regulation
Atypical_PIKK_FRAP_MTOR_ST	Q8TB45	DEPTOR	P42345	MTOR	S265	V264L	264	Missense	proximal	-1	no	12.264	12.140	EPSD;PhosphoSitePlus	TCGA;COSMIC	6.822	Down-regulation
Atypical_PIKK_FRAP_MTOR_ST	Q8TB45	DEPTOR	P42345	MTOR	S265	S265N	265	Missense	central	0	yes	12.264	0.000	EPSD;PhosphoSitePlus	TCGA;COSMIC	6.822	Loss
Atypical_PIKK_FRAP_MTOR_ST	Q8TB45	DEPTOR	P42345	MTOR	S293	F290I	290	Missense	distal	-3	no	8.165	8.529	EPSD;PhosphoSitePlus	TCGA;COSMIC	6.822	Up-regulation
Atypical_PIKK_FRAP_MTOR_ST	Q8TB45	DEPTOR	P42345	MTOR	T295	F290I	290	Missense	distal	-5	no	9.860	9.918	PhosphoSitePlus;EPSD	TCGA;COSMIC	6.822	Up-regulation
Atypical_PIKK_FRAP_MTOR_ST	Q8TB45	DEPTOR	P42345	MTOR	T321	P325L	325	Missense	distal	4	no	12.533	12.149	EPSD	TCGA;COSMIC	6.822	Down-regulation
Atypical_PIKK_FRAP_MTOR_ST	Q8TB45	DEPTOR	P42345	MTOR	T321	P325S	325	Missense	distal	4	no	12.533	12.789	EPSD	TCGA;COSMIC	6.822	Up-regulation
Atypical_PIKK_FRAP_MTOR_ST	Q8TB45	DEPTOR	P42345	MTOR	T321	V314G	314	Missense	distal	-7	no	12.533	12.699	EPSD	TCGA	6.822	Up-regulation
Atypical_PIKK_FRAP_MTOR_ST	Q8TB45	DEPTOR	P42345	MTOR	T394	R397Q	397	Missense	distal	3	no	7.371	6.105	EPSD	TCGA;COSMIC	6.822	Loss
Atypical_PIKK_FRAP_MTOR_ST	P23443	RPS6KB1	P42345	MTOR	T250	H251Y	251	Missense	proximal	1	no	-10.910	11.451	EPSD	TCGA;COSMIC	6.822	Gain
Atypical_PIKK_FRAP_MTOR_ST	P23443	RPS6KB1	P42345	MTOR	T390	Q389E	389	Missense	proximal	-1	no	8.855	8.966	EPSD	TCGA;COSMIC	6.822	Up-regulation
Atypical_PIKK_FRAP_MTOR_ST	P23443	RPS6KB1	P42345	MTOR	S394	Q389E	389	Missense	distal	-5	no	7.418	7.056	PhosphoSitePlus;EPSD	TCGA;COSMIC	6.822	Down-regulation
Atypical_PIKK_FRAP_MTOR_ST	P03372	ESR1	P42345	MTOR	S106	P113S	113	Missense	distal	7	no	8.413	8.391	PhosphoSitePlus;EPSD	TCGA;ICGC;COSMIC	6.822	Down-regulation
Atypical_PIKK_FRAP_MTOR_ST	P03372	ESR1	P42345	MTOR	S201	K206R	206	Missense	distal	5	no	6.253	7.574	EPSD	TCGA;ICGC;COSMIC	6.822	Gain
Atypical_PIKK_FRAP_MTOR_ST	P03372	ESR1	P42345	MTOR	S341	P336T	336	Missense	distal	-5	no	10.280	10.239	EPSD	TCGA;ICGC;COSMIC	6.822	Down-regulation
Atypical_PIKK_FRAP_MTOR_ST	P03372	ESR1	P42345	MTOR	S341	G344D	344	Missense	distal	3	no	10.280	8.538	EPSD	TCGA;ICGC;COSMIC	6.822	Down-regulation
Atypical_PIKK_FRAP_MTOR_ST	P03372	ESR1	P42345	MTOR	S559	T563M	563	Missense	distal	4	no	8.025	7.811	EPSD	TCGA;ICGC;COSMIC	6.822	Down-regulation
Atypical_PIKK_FRAP_MTOR_ST	P03372	ESR1	P42345	MTOR	S559	R555C	555	Missense	distal	-4	no	8.025	6.086	EPSD	TCGA;ICGC;COSMIC	6.822	Loss
Atypical_PIKK_FRAP_MTOR_ST	P03372	ESR1	P42345	MTOR	S559	R555H	555	Missense	distal	-4	no	8.025	6.832	EPSD	TCGA;ICGC;COSMIC;GDSC	6.822	Down-regulation
Atypical_PIKK_FRAP_MTOR_ST	Q9P2Y5	UVRAG	P42345	MTOR	S550	S548C	548	Missense	proximal	-2	no	8.645	8.795	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	6.822	Up-regulation
Atypical_PIKK_FRAP_MTOR_ST	Q9P2Y5	UVRAG	P42345	MTOR	S550	S554F	554	Missense	distal	4	no	8.645	8.401	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	6.822	Down-regulation
Atypical_PIKK_FRAP_MTOR_ST	Q9P2Y5	UVRAG	P42345	MTOR	S550	S546Y	546	Missense	distal	-4	no	8.645	8.014	EPSD;PhosphoSitePlus	TCGA;ICGC	6.822	Down-regulation
Atypical_PIKK_FRAP_MTOR_ST	Q9P2Y5	UVRAG	P42345	MTOR	S571	D567Y	567	Missense	distal	-4	no	7.978	6.318	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	6.822	Loss
Atypical_PIKK_FRAP_MTOR_ST	Q9P2Y5	UVRAG	P42345	MTOR	S571	G565R	565	Missense	distal	-6	no	7.978	7.963	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	6.822	Down-regulation
Atypical_PIKK_FRAP_MTOR_ST	Q9P2Y5	UVRAG	P42345	MTOR	S696	D698N	698	Missense	proximal	2	no	9.716	8.457	EPSD	TCGA;ICGC;COSMIC	6.822	Down-regulation
Atypical_PIKK_FRAP_MTOR_ST	Q9P2Y5	UVRAG	P42345	MTOR	S696	R691C	691	Missense	distal	-5	no	9.716	9.840	EPSD	TCGA;ICGC;COSMIC	6.822	Up-regulation
Atypical_PIKK_FRAP_MTOR_ST	P19484	TFEB	P42345	MTOR	S74	E77D	77	Missense	distal	3	no	8.424	7.498	EPSD	TCGA;ICGC;COSMIC	6.822	Down-regulation
Atypical_PIKK_FRAP_MTOR_ST	P19484	TFEB	P42345	MTOR	S109	P115L	115	Missense	distal	6	no	8.510	7.350	EPSD	TCGA;ICGC;COSMIC	6.822	Down-regulation
Atypical_PIKK_FRAP_MTOR_ST	P19484	TFEB	P42345	MTOR	S109	P115S	115	Missense	distal	6	no	8.510	8.540	EPSD	TCGA;ICGC;COSMIC	6.822	Up-regulation
Atypical_PIKK_FRAP_MTOR_ST	P19484	TFEB	P42345	MTOR	S114	P115L	115	Missense	proximal	1	no	8.733	2.764	EPSD	TCGA;ICGC;COSMIC	6.822	Loss
Atypical_PIKK_FRAP_MTOR_ST	P19484	TFEB	P42345	MTOR	S114	P115S	115	Missense	proximal	1	no	8.733	0.210	EPSD	TCGA;ICGC;COSMIC	6.822	Loss
Atypical_PIKK_FRAP_MTOR_ST	P19484	TFEB	P42345	MTOR	S122	G124V	124	Missense	proximal	2	no	9.332	9.496	PhosphoSitePlus;EPSD	TCGA;ICGC;COSMIC	6.822	Up-regulation
Atypical_PIKK_FRAP_MTOR_ST	P19484	TFEB	P42345	MTOR	S122	P115L	115	Missense	distal	-7	no	9.332	9.199	PhosphoSitePlus;EPSD	TCGA;ICGC;COSMIC	6.822	Down-regulation
Atypical_PIKK_FRAP_MTOR_ST	P19484	TFEB	P42345	MTOR	S122	P115S	115	Missense	distal	-7	no	9.332	9.769	PhosphoSitePlus;EPSD	TCGA;ICGC;COSMIC	6.822	Up-regulation
Atypical_PIKK_FRAP_MTOR_ST	P19484	TFEB	P42345	MTOR	S142	A135T	135	Missense	distal	-7	no	11.712	12.603	EPSD	TCGA;ICGC;COSMIC;GDSC;CCLE	6.822	Up-regulation
Atypical_PIKK_FRAP_MTOR_ST	P19484	TFEB	P42345	MTOR	S195	L191M	191	Missense	distal	-4	no	7.056	6.644	EPSD	TCGA;ICGC;COSMIC	6.822	Loss
Atypical_PIKK_FRAP_MTOR_ST	P19484	TFEB	P42345	MTOR	S195	P198S	198	Missense	distal	3	no	7.056	7.070	EPSD	TCGA;ICGC;COSMIC	6.822	Up-regulation
Atypical_PIKK_FRAP_MTOR_ST	P19484	TFEB	P42345	MTOR	S211	S211Y	211	Missense	central	0	yes	8.216	0.000	EPSD;PhosphoSitePlus	TCGA;COSMIC	6.822	Loss
Atypical_PIKK_FRAP_MTOR_ST	P19484	TFEB	P42345	MTOR	S211	A214V	214	Missense	distal	3	no	8.216	6.205	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	6.822	Loss
Atypical_PIKK_FRAP_MTOR_ST	P19484	TFEB	P42345	MTOR	S423	S423F	423	Missense	central	0	yes	8.283	0.000	EPSD	TCGA;ICGC;COSMIC	6.822	Loss
Atypical_PIKK_FRAP_MTOR_ST	P19484	TFEB	P42345	MTOR	S423	A418V	418	Missense	distal	-5	no	8.283	8.193	EPSD	TCGA;ICGC;COSMIC;GDSC;CCLE	6.822	Down-regulation
Atypical_PIKK_FRAP_MTOR_ST	P19484	TFEB	P42345	MTOR	S423	S429P	429	Missense	distal	6	no	8.283	8.253	EPSD	TCGA;ICGC	6.822	Down-regulation
Atypical_PIKK_FRAP_MTOR_ST	P19484	TFEB	P42345	MTOR	S423	S429C	429	Missense	distal	6	no	8.283	6.587	EPSD	TCGA;COSMIC	6.822	Loss
Atypical_PIKK_FRAP_MTOR_ST	P19484	TFEB	P42345	MTOR	S455	T453S	453	Missense	proximal	-2	no	14.349	14.285	EPSD	TCGA;ICGC;COSMIC	6.822	Down-regulation
Atypical_PIKK_FRAP_MTOR_ST	P19484	TFEB	P42345	MTOR	S455	T453I	453	Missense	proximal	-2	no	14.349	13.845	EPSD	TCGA;COSMIC	6.822	Down-regulation
Atypical_PIKK_FRAP_MTOR_ST	P19484	TFEB	P42345	MTOR	S455	L451P	451	Missense	distal	-4	no	14.349	14.535	EPSD	TCGA;COSMIC	6.822	Up-regulation
Atypical_PIKK_FRAP_MTOR_ST	P19484	TFEB	P42345	MTOR	S462	S467I	467	Missense	distal	5	no	10.081	10.584	EPSD	TCGA;COSMIC	6.822	Up-regulation
Atypical_PIKK_FRAP_MTOR_ST	P19484	TFEB	P42345	MTOR	S466	S467I	467	Missense	proximal	1	no	5.459	8.924	EPSD	TCGA;COSMIC	6.822	Gain
Atypical_PIKK_FRAP_MTOR_ST	P19484	TFEB	P42345	MTOR	S467	S467I	467	Missense	central	0	yes	10.630	0.000	EPSD	TCGA;COSMIC	6.822	Loss
Atypical_PIKK_FRAP_MTOR_ST	P19484	TFEB	P42345	MTOR	S469	S467I	467	Missense	proximal	-2	no	17.972	17.532	EPSD	TCGA;COSMIC	6.822	Down-regulation
Atypical_PIKK_FRAP_MTOR_ST	Q9H4L4	SENP3	P42345	MTOR	S26	P27S	27	Missense	proximal	1	no	9.652	1.128	PhosphoSitePlus;EPSD	TCGA;ICGC;COSMIC	6.822	Loss
Atypical_PIKK_FRAP_MTOR_ST	Q9H4L4	SENP3	P42345	MTOR	S26	R31H	31	Missense	distal	5	no	9.652	9.957	PhosphoSitePlus;EPSD	TCGA;ICGC;COSMIC	6.822	Up-regulation
Atypical_PIKK_FRAP_MTOR_ST	Q9H4L4	SENP3	P42345	MTOR	S26	R29W	29	Missense	distal	3	no	9.652	7.892	PhosphoSitePlus;EPSD	TCGA;ICGC;COSMIC	6.822	Down-regulation
Atypical_PIKK_FRAP_MTOR_ST	Q9H4L4	SENP3	P42345	MTOR	S26	R33H	33	Missense	distal	7	no	9.652	9.495	PhosphoSitePlus;EPSD	TCGA;ICGC;COSMIC	6.822	Down-regulation
Atypical_PIKK_FRAP_MTOR_ST	Q9H4L4	SENP3	P42345	MTOR	S26	R28S	28	Missense	proximal	2	no	9.652	11.365	PhosphoSitePlus;EPSD	TCGA;ICGC;COSMIC	6.822	Up-regulation
Atypical_PIKK_FRAP_MTOR_ST	Q9H4L4	SENP3	P42345	MTOR	S26	A23V	23	Missense	distal	-3	no	9.652	10.282	PhosphoSitePlus;EPSD	TCGA;ICGC;COSMIC	6.822	Up-regulation
Atypical_PIKK_FRAP_MTOR_ST	Q9H4L4	SENP3	P42345	MTOR	S169	G173W	173	Missense	distal	4	no	8.666	8.778	EPSD	TCGA;ICGC;COSMIC	6.822	Up-regulation
Atypical_PIKK_FRAP_MTOR_ST	Q9H4L4	SENP3	P42345	MTOR	S169	K165N	165	Missense	distal	-4	no	8.666	7.954	EPSD	TCGA;ICGC	6.822	Down-regulation
Atypical_PIKK_FRAP_MTOR_ST	Q9H4L4	SENP3	P42345	MTOR	T176	G173W	173	Missense	distal	-3	no	7.876	7.635	EPSD	TCGA;ICGC;COSMIC	6.822	Down-regulation
Atypical_PIKK_FRAP_MTOR_ST	Q9H4L4	SENP3	P42345	MTOR	S181	R185H	185	Missense	distal	4	no	9.505	9.246	EPSD	TCGA;ICGC;COSMIC	6.822	Down-regulation
Atypical_PIKK_FRAP_MTOR_ST	Q9H4L4	SENP3	P42345	MTOR	S188	P195L	195	Missense	distal	7	no	11.827	12.784	EPSD	TCGA;ICGC;COSMIC	6.822	Up-regulation
Atypical_PIKK_FRAP_MTOR_ST	Q9H4L4	SENP3	P42345	MTOR	S188	R185H	185	Missense	distal	-3	no	11.827	11.080	EPSD	TCGA;ICGC;COSMIC	6.822	Down-regulation
Atypical_PIKK_FRAP_MTOR_ST	Q9H4L4	SENP3	P42345	MTOR	S212	E206Q	206	Missense	distal	-6	no	7.513	7.441	EPSD	TCGA;ICGC;COSMIC	6.822	Down-regulation
Atypical_PIKK_FRAP_MTOR_ST	Q9H4L4	SENP3	P42345	MTOR	S212	S217Y	217	Missense	distal	5	no	7.513	8.377	EPSD	TCGA;ICGC	6.822	Up-regulation
Atypical_PIKK_FRAP_MTOR_ST	Q9H4L4	SENP3	P42345	MTOR	T229	P233S	233	Missense	distal	4	no	9.516	9.772	EPSD	TCGA;ICGC;COSMIC	6.822	Up-regulation
Atypical_PIKK_FRAP_MTOR_ST	Q9H4L4	SENP3	P42345	MTOR	T229	P233L	233	Missense	distal	4	no	9.516	9.132	EPSD	TCGA;ICGC;COSMIC	6.822	Down-regulation
Atypical_PIKK_FRAP_MTOR_ST	Q9H4L4	SENP3	P42345	MTOR	S232	P233S	233	Missense	proximal	1	no	11.290	2.766	EPSD	TCGA;ICGC;COSMIC	6.822	Loss
Atypical_PIKK_FRAP_MTOR_ST	Q9H4L4	SENP3	P42345	MTOR	S232	P233L	233	Missense	proximal	1	no	11.290	5.321	EPSD	TCGA;ICGC;COSMIC	6.822	Loss
Atypical_PIKK_FRAP_MTOR_ST	Q9H4L4	SENP3	P42345	MTOR	S307	Q305H	305	Missense	proximal	-2	no	6.870	6.300	EPSD	TCGA;ICGC	6.822	Loss
Atypical_PIKK_FRAP_MTOR_ST	Q9H4L4	SENP3	P42345	MTOR	S352	F347L	347	Missense	distal	-5	no	8.272	8.241	EPSD	TCGA;ICGC	6.822	Down-regulation
Atypical_PIKK_FRAP_MTOR_ST	Q9H4L4	SENP3	P42345	MTOR	T353	F347L	347	Missense	distal	-6	no	10.742	10.463	EPSD	TCGA;ICGC	6.822	Down-regulation
Atypical_PIKK_FRAP_MTOR_ST	Q8IYB3	SRRM1	P42345	MTOR	S171	R170G	170	Missense	proximal	-1	no	9.699	9.854	EPSD	TCGA;ICGC;COSMIC	6.822	Up-regulation
Atypical_PIKK_FRAP_MTOR_ST	Q8IYB3	SRRM1	P42345	MTOR	S179	S179Y	179	Missense	central	0	yes	12.220	0.000	EPSD	TCGA;ICGC;COSMIC	6.822	Loss
Atypical_PIKK_FRAP_MTOR_ST	Q8IYB3	SRRM1	P42345	MTOR	S179	S186Y	186	Missense	distal	7	no	12.220	11.821	EPSD	TCGA;ICGC;COSMIC	6.822	Down-regulation
Atypical_PIKK_FRAP_MTOR_ST	Q8IYB3	SRRM1	P42345	MTOR	S179	R185Q	185	Missense	distal	6	no	12.220	12.605	EPSD	TCGA;ICGC;COSMIC	6.822	Up-regulation
Atypical_PIKK_FRAP_MTOR_ST	Q8IYB3	SRRM1	P42345	MTOR	S181	P188S	188	Missense	distal	7	no	7.856	7.835	EPSD	TCGA;ICGC;COSMIC	6.822	Down-regulation
Atypical_PIKK_FRAP_MTOR_ST	Q8IYB3	SRRM1	P42345	MTOR	S181	S179Y	179	Missense	proximal	-2	no	7.856	7.314	EPSD	TCGA;ICGC;COSMIC	6.822	Down-regulation
Atypical_PIKK_FRAP_MTOR_ST	Q8IYB3	SRRM1	P42345	MTOR	S181	S186Y	186	Missense	distal	5	no	7.856	8.721	EPSD	TCGA;ICGC;COSMIC	6.822	Up-regulation
Atypical_PIKK_FRAP_MTOR_ST	Q8IYB3	SRRM1	P42345	MTOR	S181	R185Q	185	Missense	distal	4	no	7.856	7.988	EPSD	TCGA;ICGC;COSMIC	6.822	Up-regulation
Atypical_PIKK_FRAP_MTOR_ST	Q8IYB3	SRRM1	P42345	MTOR	S187	P188S	188	Missense	proximal	1	no	8.969	0.446	EPSD	TCGA;ICGC;COSMIC	6.822	Loss
Atypical_PIKK_FRAP_MTOR_ST	Q8IYB3	SRRM1	P42345	MTOR	S187	V189D	189	Missense	proximal	2	no	8.969	8.842	EPSD	TCGA;ICGC;COSMIC	6.822	Down-regulation
Atypical_PIKK_FRAP_MTOR_ST	Q8IYB3	SRRM1	P42345	MTOR	S187	V189I	189	Missense	proximal	2	no	8.969	8.938	EPSD	TCGA;ICGC	6.822	Down-regulation
Atypical_PIKK_FRAP_MTOR_ST	Q8IYB3	SRRM1	P42345	MTOR	S187	S186Y	186	Missense	proximal	-1	no	8.969	8.796	EPSD	TCGA;ICGC;COSMIC	6.822	Down-regulation
Atypical_PIKK_FRAP_MTOR_ST	Q8IYB3	SRRM1	P42345	MTOR	S187	R185Q	185	Missense	proximal	-2	no	8.969	9.309	EPSD	TCGA;ICGC;COSMIC	6.822	Up-regulation
Atypical_PIKK_FRAP_MTOR_ST	Q8IYB3	SRRM1	P42345	MTOR	S209	K206T	206	Missense	distal	-3	no	10.325	10.254	EPSD	TCGA;ICGC;COSMIC	6.822	Down-regulation
Atypical_PIKK_FRAP_MTOR_ST	Q8IYB3	SRRM1	P42345	MTOR	S209	R202C	202	Missense	distal	-7	no	10.325	9.230	EPSD	TCGA;ICGC;COSMIC	6.822	Down-regulation
Atypical_PIKK_FRAP_MTOR_ST	Q8IYB3	SRRM1	P42345	MTOR	S310	R314W	314	Missense	distal	4	no	9.567	9.729	EPSD	TCGA;COSMIC	6.822	Up-regulation
Atypical_PIKK_FRAP_MTOR_ST	Q8IYB3	SRRM1	P42345	MTOR	S310	P317L	317	Missense	distal	7	no	9.567	10.523	EPSD	TCGA;COSMIC	6.822	Up-regulation
Atypical_PIKK_FRAP_MTOR_ST	Q8IYB3	SRRM1	P42345	MTOR	S316	R314W	314	Missense	proximal	-2	no	15.324	15.025	EPSD	TCGA;COSMIC	6.822	Down-regulation
Atypical_PIKK_FRAP_MTOR_ST	Q8IYB3	SRRM1	P42345	MTOR	S316	P317L	317	Missense	proximal	1	no	15.324	9.354	EPSD	TCGA;COSMIC	6.822	Down-regulation
Atypical_PIKK_FRAP_MTOR_ST	Q8IYB3	SRRM1	P42345	MTOR	S322	P317L	317	Missense	distal	-5	no	9.409	9.338	EPSD	TCGA;COSMIC	6.822	Down-regulation
Atypical_PIKK_FRAP_MTOR_ST	Q8IYB3	SRRM1	P42345	MTOR	S369	R366H	366	Missense	distal	-3	no	10.532	9.785	EPSD	TCGA;COSMIC	6.822	Down-regulation
Atypical_PIKK_FRAP_MTOR_ST	Q8IYB3	SRRM1	P42345	MTOR	S369	R366C	366	Missense	distal	-3	no	10.532	9.820	EPSD	TCGA;COSMIC	6.822	Down-regulation
Atypical_PIKK_FRAP_MTOR_ST	Q8IYB3	SRRM1	P42345	MTOR	S369	P375S	375	Missense	distal	6	no	10.532	10.562	EPSD	TCGA;ICGC;COSMIC	6.822	Up-regulation
Atypical_PIKK_FRAP_MTOR_ST	Q8IYB3	SRRM1	P42345	MTOR	S369	P375L	375	Missense	distal	6	no	10.532	9.372	EPSD	TCGA;COSMIC	6.822	Down-regulation
Atypical_PIKK_FRAP_MTOR_ST	Q8IYB3	SRRM1	P42345	MTOR	S380	P375S	375	Missense	distal	-5	no	7.314	7.266	EPSD	TCGA;ICGC;COSMIC	6.822	Down-regulation
Atypical_PIKK_FRAP_MTOR_ST	Q8IYB3	SRRM1	P42345	MTOR	S380	P375L	375	Missense	distal	-5	no	7.314	7.242	EPSD	TCGA;COSMIC	6.822	Down-regulation
Atypical_PIKK_FRAP_MTOR_ST	Q8IYB3	SRRM1	P42345	MTOR	S380	S380N	380	Missense	central	0	yes	7.314	0.000	EPSD	TCGA;COSMIC	6.822	Loss
Atypical_PIKK_FRAP_MTOR_ST	Q8IYB3	SRRM1	P42345	MTOR	S389	P394S	394	Missense	distal	5	no	11.652	11.538	EPSD	TCGA;COSMIC	6.822	Down-regulation
Atypical_PIKK_FRAP_MTOR_ST	Q8IYB3	SRRM1	P42345	MTOR	S393	P394S	394	Missense	proximal	1	no	9.338	0.814	EPSD	TCGA;COSMIC	6.822	Loss
Atypical_PIKK_FRAP_MTOR_ST	Q8IYB3	SRRM1	P42345	MTOR	T406	R412W	412	Missense	distal	6	no	6.403	6.933	EPSD	TCGA	6.822	Gain
Atypical_PIKK_FRAP_MTOR_ST	Q8IYB3	SRRM1	P42345	MTOR	S414	T416I	416	Missense	proximal	2	no	14.162	14.174	EPSD	TCGA;ICGC;COSMIC	6.822	Up-regulation
Atypical_PIKK_FRAP_MTOR_ST	Q8IYB3	SRRM1	P42345	MTOR	S414	R412W	412	Missense	proximal	-2	no	14.162	13.864	EPSD	TCGA	6.822	Down-regulation
Atypical_PIKK_FRAP_MTOR_ST	Q8IYB3	SRRM1	P42345	MTOR	S450	S452L	452	Missense	proximal	2	no	8.471	8.276	EPSD	TCGA;ICGC;COSMIC	6.822	Down-regulation
Atypical_PIKK_FRAP_MTOR_ST	Q8IYB3	SRRM1	P42345	MTOR	S452	S452L	452	Missense	central	0	yes	8.651	0.000	EPSD	TCGA;ICGC;COSMIC	6.822	Loss
Atypical_PIKK_FRAP_MTOR_ST	Q8IYB3	SRRM1	P42345	MTOR	S498	D504N	504	Missense	distal	6	no	8.542	7.591	EPSD	TCGA;COSMIC	6.822	Down-regulation
Atypical_PIKK_FRAP_MTOR_ST	Q8IYB3	SRRM1	P42345	MTOR	S498	S501P	501	Missense	distal	3	no	8.542	8.528	EPSD	TCGA;ICGC;COSMIC	6.822	Down-regulation
Atypical_PIKK_FRAP_MTOR_ST	Q8IYB3	SRRM1	P42345	MTOR	S498	Q491P	491	Missense	distal	-7	no	8.542	8.941	EPSD	TCGA;ICGC	6.822	Up-regulation
Atypical_PIKK_FRAP_MTOR_ST	Q8IYB3	SRRM1	P42345	MTOR	S501	D504N	504	Missense	distal	3	no	7.118	7.250	EPSD	TCGA;COSMIC	6.822	Up-regulation
Atypical_PIKK_FRAP_MTOR_ST	Q8IYB3	SRRM1	P42345	MTOR	S501	S501P	501	Missense	central	0	yes	7.118	0.000	EPSD	TCGA;ICGC;COSMIC	6.822	Loss
Atypical_PIKK_FRAP_MTOR_ST	Q8IYB3	SRRM1	P42345	MTOR	S501	P507L	507	Missense	distal	6	no	7.118	5.959	EPSD	TCGA;COSMIC	6.822	Loss
Atypical_PIKK_FRAP_MTOR_ST	Q8IYB3	SRRM1	P42345	MTOR	S524	S528G	528	Missense	distal	4	no	11.164	10.641	EPSD	TCGA;COSMIC	6.822	Down-regulation
Atypical_PIKK_FRAP_MTOR_ST	Q8IYB3	SRRM1	P42345	MTOR	S524	R520W	520	Missense	distal	-4	no	11.164	11.273	EPSD	TCGA;COSMIC	6.822	Up-regulation
Atypical_PIKK_FRAP_MTOR_ST	Q8IYB3	SRRM1	P42345	MTOR	S524	S526F	526	Missense	proximal	2	no	11.164	9.429	EPSD	TCGA;COSMIC;CCLE	6.822	Down-regulation
Atypical_PIKK_FRAP_MTOR_ST	Q8IYB3	SRRM1	P42345	MTOR	S530	S528G	528	Missense	proximal	-2	no	8.980	9.710	EPSD	TCGA;COSMIC	6.822	Up-regulation
Atypical_PIKK_FRAP_MTOR_ST	Q8IYB3	SRRM1	P42345	MTOR	S530	S526F	526	Missense	distal	-4	no	8.980	9.005	EPSD	TCGA;COSMIC;CCLE	6.822	Up-regulation
Atypical_PIKK_FRAP_MTOR_ST	Q8IYB3	SRRM1	P42345	MTOR	S532	S528G	528	Missense	distal	-4	no	8.323	7.756	EPSD	TCGA;COSMIC	6.822	Down-regulation
Atypical_PIKK_FRAP_MTOR_ST	Q8IYB3	SRRM1	P42345	MTOR	S532	S526F	526	Missense	distal	-6	no	8.323	7.848	EPSD	TCGA;COSMIC;CCLE	6.822	Down-regulation
Atypical_PIKK_FRAP_MTOR_ST	Q8IYB3	SRRM1	P42345	MTOR	S541	R546W	546	Missense	distal	5	no	7.464	6.481	EPSD	TCGA;ICGC	6.822	Loss
Atypical_PIKK_FRAP_MTOR_ST	Q8IYB3	SRRM1	P42345	MTOR	S549	S551F	551	Missense	proximal	2	no	13.097	11.363	EPSD	TCGA;COSMIC	6.822	Down-regulation
Atypical_PIKK_FRAP_MTOR_ST	Q8IYB3	SRRM1	P42345	MTOR	S549	R546W	546	Missense	distal	-3	no	13.097	12.881	EPSD	TCGA;ICGC	6.822	Down-regulation
Atypical_PIKK_FRAP_MTOR_ST	Q8IYB3	SRRM1	P42345	MTOR	S551	S551F	551	Missense	central	0	yes	8.444	0.000	EPSD	TCGA;COSMIC	6.822	Loss
Atypical_PIKK_FRAP_MTOR_ST	Q8IYB3	SRRM1	P42345	MTOR	S551	R546W	546	Missense	distal	-5	no	8.444	8.502	EPSD	TCGA;ICGC	6.822	Up-regulation
Atypical_PIKK_FRAP_MTOR_ST	Q8IYB3	SRRM1	P42345	MTOR	S560	P563L	563	Missense	distal	3	no	9.545	7.290	EPSD	TCGA;COSMIC	6.822	Down-regulation
Atypical_PIKK_FRAP_MTOR_ST	Q8IYB3	SRRM1	P42345	MTOR	S560	P566S	566	Missense	distal	6	no	9.545	9.574	EPSD	TCGA;COSMIC	6.822	Up-regulation
Atypical_PIKK_FRAP_MTOR_ST	Q8IYB3	SRRM1	P42345	MTOR	S560	P561S	561	Missense	proximal	1	no	9.545	1.021	EPSD	TCGA;COSMIC	6.822	Loss
Atypical_PIKK_FRAP_MTOR_ST	Q8IYB3	SRRM1	P42345	MTOR	S560	P567S	567	Missense	distal	7	no	9.545	9.523	EPSD	TCGA;COSMIC	6.822	Down-regulation
Atypical_PIKK_FRAP_MTOR_ST	Q8IYB3	SRRM1	P42345	MTOR	S562	R568Q	568	Missense	distal	6	no	7.199	7.583	EPSD	TCGA;COSMIC	6.822	Up-regulation
Atypical_PIKK_FRAP_MTOR_ST	Q8IYB3	SRRM1	P42345	MTOR	S562	P563L	563	Missense	proximal	1	no	7.199	1.230	EPSD	TCGA;COSMIC	6.822	Loss
Atypical_PIKK_FRAP_MTOR_ST	Q8IYB3	SRRM1	P42345	MTOR	S562	P566S	566	Missense	distal	4	no	7.199	7.454	EPSD	TCGA;COSMIC	6.822	Up-regulation
Atypical_PIKK_FRAP_MTOR_ST	Q8IYB3	SRRM1	P42345	MTOR	S562	P561S	561	Missense	proximal	-1	no	7.199	7.267	EPSD	TCGA;COSMIC	6.822	Up-regulation
Atypical_PIKK_FRAP_MTOR_ST	Q8IYB3	SRRM1	P42345	MTOR	S562	P567S	567	Missense	distal	5	no	7.199	7.085	EPSD	TCGA;COSMIC	6.822	Down-regulation
Atypical_PIKK_FRAP_MTOR_ST	Q8IYB3	SRRM1	P42345	MTOR	T572	R568Q	568	Missense	distal	-4	no	7.638	7.141	EPSD;PhosphoSitePlus	TCGA;COSMIC	6.822	Down-regulation
Atypical_PIKK_FRAP_MTOR_ST	Q8IYB3	SRRM1	P42345	MTOR	T572	P566S	566	Missense	distal	-6	no	7.638	7.618	EPSD;PhosphoSitePlus	TCGA;COSMIC	6.822	Down-regulation
Atypical_PIKK_FRAP_MTOR_ST	Q8IYB3	SRRM1	P42345	MTOR	T572	P567S	567	Missense	distal	-5	no	7.638	7.590	EPSD;PhosphoSitePlus	TCGA;COSMIC	6.822	Down-regulation
Atypical_PIKK_FRAP_MTOR_ST	Q8IYB3	SRRM1	P42345	MTOR	T572	R578Q	578	Missense	distal	6	no	7.638	8.022	EPSD;PhosphoSitePlus	TCGA;COSMIC	6.822	Up-regulation
Atypical_PIKK_FRAP_MTOR_ST	Q8IYB3	SRRM1	P42345	MTOR	T574	R568Q	568	Missense	distal	-6	no	9.794	9.530	PhosphoSitePlus;EPSD	TCGA;COSMIC	6.822	Down-regulation
Atypical_PIKK_FRAP_MTOR_ST	Q8IYB3	SRRM1	P42345	MTOR	T574	P567S	567	Missense	distal	-7	no	9.794	10.231	PhosphoSitePlus;EPSD	TCGA;COSMIC	6.822	Up-regulation
Atypical_PIKK_FRAP_MTOR_ST	Q8IYB3	SRRM1	P42345	MTOR	T574	R578Q	578	Missense	distal	4	no	9.794	9.926	PhosphoSitePlus;EPSD	TCGA;COSMIC	6.822	Up-regulation
Atypical_PIKK_FRAP_MTOR_ST	Q8IYB3	SRRM1	P42345	MTOR	T581	R578Q	578	Missense	distal	-3	no	8.125	7.517	EPSD	TCGA;COSMIC	6.822	Down-regulation
Atypical_PIKK_FRAP_MTOR_ST	Q8IYB3	SRRM1	P42345	MTOR	S583	R589H	589	Missense	distal	6	no	12.711	13.027	EPSD	TCGA;COSMIC;CCLE	6.822	Up-regulation
Atypical_PIKK_FRAP_MTOR_ST	Q8IYB3	SRRM1	P42345	MTOR	S583	R578Q	578	Missense	distal	-5	no	12.711	12.626	EPSD	TCGA;COSMIC	6.822	Down-regulation
Atypical_PIKK_FRAP_MTOR_ST	Q8IYB3	SRRM1	P42345	MTOR	S590	S592C	592	Missense	proximal	2	no	12.644	11.098	EPSD	TCGA;COSMIC	6.822	Down-regulation
Atypical_PIKK_FRAP_MTOR_ST	Q8IYB3	SRRM1	P42345	MTOR	S590	R589H	589	Missense	proximal	-1	no	12.644	12.685	EPSD	TCGA;COSMIC;CCLE	6.822	Up-regulation
Atypical_PIKK_FRAP_MTOR_ST	Q8IYB3	SRRM1	P42345	MTOR	S590	S597Y	597	Missense	distal	7	no	12.644	12.246	EPSD	TCGA	6.822	Down-regulation
Atypical_PIKK_FRAP_MTOR_ST	Q8IYB3	SRRM1	P42345	MTOR	S592	S592C	592	Missense	central	0	yes	8.159	0.000	EPSD	TCGA;COSMIC	6.822	Loss
Atypical_PIKK_FRAP_MTOR_ST	Q8IYB3	SRRM1	P42345	MTOR	S592	R589H	589	Missense	distal	-3	no	8.159	7.412	EPSD	TCGA;COSMIC;CCLE	6.822	Down-regulation
Atypical_PIKK_FRAP_MTOR_ST	Q8IYB3	SRRM1	P42345	MTOR	S592	S597Y	597	Missense	distal	5	no	8.159	9.024	EPSD	TCGA	6.822	Up-regulation
Atypical_PIKK_FRAP_MTOR_ST	Q8IYB3	SRRM1	P42345	MTOR	S605	S607F	607	Missense	proximal	2	no	12.357	10.623	EPSD	TCGA;GDSC;CCLE	6.822	Down-regulation
Atypical_PIKK_FRAP_MTOR_ST	Q8IYB3	SRRM1	P42345	MTOR	S605	K611N	611	Missense	distal	6	no	12.357	11.859	EPSD	TCGA;COSMIC	6.822	Down-regulation
Atypical_PIKK_FRAP_MTOR_ST	Q8IYB3	SRRM1	P42345	MTOR	S607	S607F	607	Missense	central	0	yes	8.255	0.000	EPSD	TCGA;GDSC;CCLE	6.822	Loss
Atypical_PIKK_FRAP_MTOR_ST	Q8IYB3	SRRM1	P42345	MTOR	S607	K611N	611	Missense	distal	4	no	8.255	8.051	EPSD	TCGA;COSMIC	6.822	Down-regulation
Atypical_PIKK_FRAP_MTOR_ST	Q8IYB3	SRRM1	P42345	MTOR	S616	K611N	611	Missense	distal	-5	no	12.806	12.731	EPSD	TCGA;COSMIC	6.822	Down-regulation
Atypical_PIKK_FRAP_MTOR_ST	Q8IYB3	SRRM1	P42345	MTOR	S626	K632E	632	Missense	distal	6	no	7.806	8.711	EPSD	TCGA;COSMIC	6.822	Up-regulation
Atypical_PIKK_FRAP_MTOR_ST	Q8IYB3	SRRM1	P42345	MTOR	S626	R633W	633	Missense	distal	7	no	7.806	7.420	EPSD	TCGA;COSMIC	6.822	Down-regulation
Atypical_PIKK_FRAP_MTOR_ST	Q8IYB3	SRRM1	P42345	MTOR	S628	K632E	632	Missense	distal	4	no	9.864	9.902	EPSD	TCGA;COSMIC	6.822	Up-regulation
Atypical_PIKK_FRAP_MTOR_ST	Q8IYB3	SRRM1	P42345	MTOR	S628	R633W	633	Missense	distal	5	no	9.864	8.881	EPSD	TCGA;COSMIC	6.822	Down-regulation
Atypical_PIKK_FRAP_MTOR_ST	Q8IYB3	SRRM1	P42345	MTOR	S638	R644G	644	Missense	distal	6	no	11.852	13.604	EPSD	TCGA;COSMIC	6.822	Up-regulation
Atypical_PIKK_FRAP_MTOR_ST	Q8IYB3	SRRM1	P42345	MTOR	S638	S636F	636	Missense	proximal	-2	no	11.852	12.030	EPSD	TCGA;ICGC;COSMIC	6.822	Up-regulation
Atypical_PIKK_FRAP_MTOR_ST	Q8IYB3	SRRM1	P42345	MTOR	S638	K632E	632	Missense	distal	-6	no	11.852	11.998	EPSD	TCGA;COSMIC	6.822	Up-regulation
Atypical_PIKK_FRAP_MTOR_ST	Q8IYB3	SRRM1	P42345	MTOR	S638	R633W	633	Missense	distal	-5	no	11.852	11.909	EPSD	TCGA;COSMIC	6.822	Up-regulation
Atypical_PIKK_FRAP_MTOR_ST	Q8IYB3	SRRM1	P42345	MTOR	S646	R652C	652	Missense	distal	6	no	9.843	9.970	EPSD	TCGA;ICGC;COSMIC	6.822	Up-regulation
Atypical_PIKK_FRAP_MTOR_ST	Q8IYB3	SRRM1	P42345	MTOR	S646	R644G	644	Missense	proximal	-2	no	9.843	10.700	EPSD	TCGA;COSMIC	6.822	Up-regulation
Atypical_PIKK_FRAP_MTOR_ST	Q8IYB3	SRRM1	P42345	MTOR	S685	P686S	686	Missense	proximal	1	no	10.720	2.196	EPSD	TCGA;COSMIC	6.822	Loss
Atypical_PIKK_FRAP_MTOR_ST	Q8IYB3	SRRM1	P42345	MTOR	S685	Q692E	692	Missense	distal	7	no	10.720	9.877	EPSD	TCGA;COSMIC	6.822	Down-regulation
Atypical_PIKK_FRAP_MTOR_ST	Q8IYB3	SRRM1	P42345	MTOR	S685	S683L	683	Missense	proximal	-2	no	10.720	10.585	EPSD	TCGA;COSMIC	6.822	Down-regulation
Atypical_PIKK_FRAP_MTOR_ST	Q8IYB3	SRRM1	P42345	MTOR	S685	P678S	678	Missense	distal	-7	no	10.720	11.157	EPSD	TCGA;ICGC;COSMIC	6.822	Up-regulation
Atypical_PIKK_FRAP_MTOR_ST	Q8IYB3	SRRM1	P42345	MTOR	S685	R689Q	689	Missense	distal	4	no	10.720	10.852	EPSD	TCGA;ICGC;COSMIC;GDSC;CCLE	6.822	Up-regulation
Atypical_PIKK_FRAP_MTOR_ST	Q8IYB3	SRRM1	P42345	MTOR	S696	Q692E	692	Missense	distal	-4	no	9.815	10.076	EPSD	TCGA;COSMIC	6.822	Up-regulation
Atypical_PIKK_FRAP_MTOR_ST	Q8IYB3	SRRM1	P42345	MTOR	S696	P697L	697	Missense	proximal	1	no	9.815	3.845	EPSD	TCGA;COSMIC	6.822	Loss
Atypical_PIKK_FRAP_MTOR_ST	Q8IYB3	SRRM1	P42345	MTOR	S696	V700I	700	Missense	distal	4	no	9.815	9.691	EPSD	TCGA;COSMIC	6.822	Down-regulation
Atypical_PIKK_FRAP_MTOR_ST	Q8IYB3	SRRM1	P42345	MTOR	S696	R701Q	701	Missense	distal	5	no	9.815	9.007	EPSD	TCGA;ICGC;COSMIC	6.822	Down-regulation
Atypical_PIKK_FRAP_MTOR_ST	Q8IYB3	SRRM1	P42345	MTOR	S696	R689Q	689	Missense	distal	-7	no	9.815	9.737	EPSD	TCGA;ICGC;COSMIC;GDSC;CCLE	6.822	Down-regulation
Atypical_PIKK_FRAP_MTOR_ST	Q8IYB3	SRRM1	P42345	MTOR	S713	T718A	718	Missense	distal	5	no	9.994	10.819	EPSD	TCGA;COSMIC	6.822	Up-regulation
Atypical_PIKK_FRAP_MTOR_ST	Q8IYB3	SRRM1	P42345	MTOR	S713	P720S	720	Missense	distal	7	no	9.994	9.973	EPSD	TCGA;COSMIC	6.822	Down-regulation
Atypical_PIKK_FRAP_MTOR_ST	Q8IYB3	SRRM1	P42345	MTOR	S713	P720L	720	Missense	distal	7	no	9.994	10.950	EPSD	TCGA;COSMIC	6.822	Up-regulation
Atypical_PIKK_FRAP_MTOR_ST	Q8IYB3	SRRM1	P42345	MTOR	S713	R710I	710	Missense	distal	-3	no	9.994	10.083	EPSD	TCGA;COSMIC	6.822	Up-regulation
Atypical_PIKK_FRAP_MTOR_ST	Q8IYB3	SRRM1	P42345	MTOR	S715	T718A	718	Missense	distal	3	no	11.835	13.297	EPSD	TCGA;COSMIC	6.822	Up-regulation
Atypical_PIKK_FRAP_MTOR_ST	Q8IYB3	SRRM1	P42345	MTOR	S715	P720S	720	Missense	distal	5	no	11.835	11.722	EPSD	TCGA;COSMIC	6.822	Down-regulation
Atypical_PIKK_FRAP_MTOR_ST	Q8IYB3	SRRM1	P42345	MTOR	S715	P720L	720	Missense	distal	5	no	11.835	13.208	EPSD	TCGA;COSMIC	6.822	Up-regulation
Atypical_PIKK_FRAP_MTOR_ST	Q8IYB3	SRRM1	P42345	MTOR	S715	R710I	710	Missense	distal	-5	no	11.835	11.759	EPSD	TCGA;COSMIC	6.822	Down-regulation
Atypical_PIKK_FRAP_MTOR_ST	Q8IYB3	SRRM1	P42345	MTOR	T727	P720S	720	Missense	distal	-7	no	10.270	10.707	EPSD	TCGA;COSMIC	6.822	Up-regulation
Atypical_PIKK_FRAP_MTOR_ST	Q8IYB3	SRRM1	P42345	MTOR	T727	P720L	720	Missense	distal	-7	no	10.270	10.137	EPSD	TCGA;COSMIC	6.822	Down-regulation
Atypical_PIKK_FRAP_MTOR_ST	Q8IYB3	SRRM1	P42345	MTOR	T727	K732T	732	Missense	distal	5	no	10.270	10.202	EPSD	TCGA;ICGC;COSMIC	6.822	Down-regulation
Atypical_PIKK_FRAP_MTOR_ST	Q8IYB3	SRRM1	P42345	MTOR	S738	K732T	732	Missense	distal	-6	no	9.279	9.451	EPSD	TCGA;ICGC;COSMIC	6.822	Up-regulation
Atypical_PIKK_FRAP_MTOR_ST	Q8IYB3	SRRM1	P42345	MTOR	S740	R746T	746	Missense	distal	6	no	8.098	9.006	EPSD	TCGA;COSMIC	6.822	Up-regulation
Atypical_PIKK_FRAP_MTOR_ST	Q8IYB3	SRRM1	P42345	MTOR	S756	A760V	760	Missense	distal	4	no	10.971	11.133	EPSD	TCGA;COSMIC	6.822	Up-regulation
Atypical_PIKK_FRAP_MTOR_ST	Q8IYB3	SRRM1	P42345	MTOR	S769	P776L	776	Missense	distal	7	no	6.891	7.847	EPSD	TCGA;COSMIC	6.822	Up-regulation
Atypical_PIKK_FRAP_MTOR_ST	Q8IYB3	SRRM1	P42345	MTOR	S769	P768S	768	Missense	proximal	-1	no	6.891	6.959	EPSD	TCGA;COSMIC	6.822	Up-regulation
Atypical_PIKK_FRAP_MTOR_ST	Q8IYB3	SRRM1	P42345	MTOR	S775	P776L	776	Missense	proximal	1	no	9.889	3.919	EPSD	TCGA;COSMIC	6.822	Loss
Atypical_PIKK_FRAP_MTOR_ST	Q8IYB3	SRRM1	P42345	MTOR	S775	P768S	768	Missense	distal	-7	no	9.889	10.326	EPSD	TCGA;COSMIC	6.822	Up-regulation
Atypical_PIKK_FRAP_MTOR_ST	Q8IYB3	SRRM1	P42345	MTOR	S775	N779K	779	Missense	distal	4	no	9.889	10.092	EPSD	TCGA;ICGC;COSMIC	6.822	Up-regulation
Atypical_PIKK_FRAP_MTOR_ST	Q8IYB3	SRRM1	P42345	MTOR	S791	K788Q	788	Missense	distal	-3	no	9.063	9.169	EPSD	TCGA	6.822	Up-regulation
Atypical_PIKK_FRAP_MTOR_ST	Q8IYB3	SRRM1	P42345	MTOR	S791	P796L	796	Missense	distal	5	no	9.063	10.436	EPSD	TCGA;COSMIC	6.822	Up-regulation
Atypical_PIKK_FRAP_MTOR_ST	Q8IYB3	SRRM1	P42345	MTOR	S791	P785L	785	Missense	distal	-6	no	9.063	8.288	EPSD	TCGA;ICGC;COSMIC	6.822	Down-regulation
Atypical_PIKK_FRAP_MTOR_ST	Q8IYB3	SRRM1	P42345	MTOR	S791	K788M	788	Missense	distal	-3	no	9.063	8.578	EPSD	TCGA	6.822	Down-regulation
Atypical_PIKK_FRAP_MTOR_ST	Q8IYB3	SRRM1	P42345	MTOR	S795	R800K	800	Missense	distal	5	no	11.414	10.093	EPSD	TCGA;COSMIC	6.822	Down-regulation
Atypical_PIKK_FRAP_MTOR_ST	Q8IYB3	SRRM1	P42345	MTOR	S795	K788Q	788	Missense	distal	-7	no	11.414	11.191	EPSD	TCGA	6.822	Down-regulation
Atypical_PIKK_FRAP_MTOR_ST	Q8IYB3	SRRM1	P42345	MTOR	S795	P796L	796	Missense	proximal	1	no	11.414	5.444	EPSD	TCGA;COSMIC	6.822	Loss
Atypical_PIKK_FRAP_MTOR_ST	Q8IYB3	SRRM1	P42345	MTOR	S795	K788M	788	Missense	distal	-7	no	11.414	11.439	EPSD	TCGA	6.822	Up-regulation
Atypical_PIKK_FRAP_MTOR_ST	Q8IYB3	SRRM1	P42345	MTOR	S797	R800K	800	Missense	distal	3	no	16.250	15.151	EPSD	TCGA;COSMIC	6.822	Down-regulation
Atypical_PIKK_FRAP_MTOR_ST	Q8IYB3	SRRM1	P42345	MTOR	S797	P796L	796	Missense	proximal	-1	no	16.250	16.116	EPSD	TCGA;COSMIC	6.822	Down-regulation
Atypical_PIKK_FRAP_MTOR_ST	Q8IYB3	SRRM1	P42345	MTOR	S901	A898V	898	Missense	distal	-3	no	17.196	17.826	EPSD	TCGA;ICGC;COSMIC	6.822	Up-regulation
Atypical_PIKK_FRAP_MTOR_ST	P51397	DAP	P42345	MTOR	S51	E46Q	46	Missense	distal	-5	no	7.608	7.971	PhosphoSitePlus	TCGA;ICGC;COSMIC	6.822	Up-regulation
Atypical_PIKK_FRAP_MTOR_ST	P51397	DAP	P42345	MTOR	S91	R93T	93	Missense	proximal	2	no	15.928	17.582	EPSD	TCGA;ICGC;COSMIC	6.822	Up-regulation
Atypical_PIKK_FRAP_MTOR_ST	P51397	DAP	P42345	MTOR	S91	M86V	86	Missense	distal	-5	no	15.928	15.872	EPSD	TCGA;ICGC;COSMIC	6.822	Down-regulation
Atypical_PIKK_FRAP_MTOR_ST	O95817	BAG3	P42345	MTOR	S134	A127T	127	Missense	distal	-7	no	6.773	7.664	EPSD	TCGA;ICGC;COSMIC	6.822	Gain
Atypical_PIKK_FRAP_MTOR_ST	O95817	BAG3	P42345	MTOR	S136	S136L	136	Missense	central	0	yes	7.958	0.000	EPSD	TCGA;ICGC;COSMIC	6.822	Loss
Atypical_PIKK_FRAP_MTOR_ST	O95817	BAG3	P42345	MTOR	S136	A129V	129	Missense	distal	-7	no	7.958	8.069	EPSD	TCGA;ICGC;COSMIC	6.822	Up-regulation
Atypical_PIKK_FRAP_MTOR_ST	O95817	BAG3	P42345	MTOR	S173	R170W	170	Missense	distal	-3	no	9.376	9.160	EPSD	TCGA;ICGC;COSMIC	6.822	Down-regulation
Atypical_PIKK_FRAP_MTOR_ST	O95817	BAG3	P42345	MTOR	S187	R193K	193	Missense	distal	6	no	6.672	7.759	EPSD	TCGA;ICGC;COSMIC	6.822	Gain
Atypical_PIKK_FRAP_MTOR_ST	O95817	BAG3	P42345	MTOR	S187	S194N	194	Missense	distal	7	no	6.672	7.271	EPSD	TCGA;ICGC	6.822	Gain
Atypical_PIKK_FRAP_MTOR_ST	O95817	BAG3	P42345	MTOR	S207	E213K	213	Missense	distal	6	no	7.046	6.142	EPSD	TCGA;ICGC	6.822	Loss
Atypical_PIKK_FRAP_MTOR_ST	O95817	BAG3	P42345	MTOR	S207	E213G	213	Missense	distal	6	no	7.046	6.808	EPSD	TCGA;ICGC;COSMIC	6.822	Loss
Atypical_PIKK_FRAP_MTOR_ST	O95817	BAG3	P42345	MTOR	S207	G204W	204	Missense	distal	-3	no	7.046	6.805	EPSD	TCGA;ICGC;COSMIC	6.822	Loss
Atypical_PIKK_FRAP_MTOR_ST	O95817	BAG3	P42345	MTOR	S207	R203W	203	Missense	distal	-4	no	7.046	7.156	EPSD	TCGA;ICGC;COSMIC	6.822	Up-regulation
Atypical_PIKK_FRAP_MTOR_ST	O95817	BAG3	P42345	MTOR	S207	H212Q	212	Missense	distal	5	no	7.046	5.934	EPSD	TCGA;ICGC;COSMIC	6.822	Loss
Atypical_PIKK_FRAP_MTOR_ST	O95817	BAG3	P42345	MTOR	S264	R261Q	261	Missense	distal	-3	no	10.328	9.719	EPSD	TCGA;ICGC;COSMIC	6.822	Down-regulation
Atypical_PIKK_FRAP_MTOR_ST	O95817	BAG3	P42345	MTOR	S269	R276L	276	Missense	distal	7	no	7.798	7.982	EPSD	TCGA;ICGC;COSMIC	6.822	Up-regulation
Atypical_PIKK_FRAP_MTOR_ST	O95817	BAG3	P42345	MTOR	S279	R276L	276	Missense	distal	-3	no	12.887	12.956	EPSD	TCGA;ICGC;COSMIC	6.822	Up-regulation
Atypical_PIKK_FRAP_MTOR_ST	O95817	BAG3	P42345	MTOR	T285	P292L	292	Missense	distal	7	no	8.855	9.811	PhosphoSitePlus;EPSD	TCGA;ICGC;COSMIC	6.822	Up-regulation
Atypical_PIKK_FRAP_MTOR_ST	O95817	BAG3	P42345	MTOR	S289	R294H	294	Missense	distal	5	no	14.805	15.110	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	6.822	Up-regulation
Atypical_PIKK_FRAP_MTOR_ST	O95817	BAG3	P42345	MTOR	S289	P292L	292	Missense	distal	3	no	14.805	12.551	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	6.822	Down-regulation
Atypical_PIKK_FRAP_MTOR_ST	O95817	BAG3	P42345	MTOR	S291	R294H	294	Missense	distal	3	no	11.061	11.231	EPSD	TCGA;ICGC;COSMIC	6.822	Up-regulation
Atypical_PIKK_FRAP_MTOR_ST	O95817	BAG3	P42345	MTOR	S291	P292L	292	Missense	proximal	1	no	11.061	5.092	EPSD	TCGA;ICGC;COSMIC	6.822	Loss
Atypical_PIKK_FRAP_MTOR_ST	O95817	BAG3	P42345	MTOR	S386	S386F	386	Missense	central	0	yes	10.169	0.000	EPSD	TCGA;ICGC;COSMIC	6.822	Loss
Atypical_PIKK_FRAP_MTOR_ST	O95817	BAG3	P42345	MTOR	T406	A401T	401	Missense	distal	-5	no	9.329	9.309	EPSD	TCGA;ICGC	6.822	Down-regulation
Atypical_PIKK_FRAP_MTOR_ST	O95817	BAG3	P42345	MTOR	S560	P562S	562	Missense	proximal	2	no	7.205	6.711	EPSD	TCGA;ICGC	6.822	Loss
Atypical_PIKK_FRAP_MTOR_ST	O95817	BAG3	P42345	MTOR	S560	A557T	557	Missense	distal	-3	no	7.205	7.259	EPSD	TCGA;ICGC;COSMIC	6.822	Up-regulation
Atypical_PIKK_FRAP_MTOR_ST	O95817	BAG3	P42345	MTOR	S564	P562S	562	Missense	proximal	-2	no	12.763	12.407	EPSD	TCGA;ICGC	6.822	Down-regulation
Atypical_PIKK_FRAP_MTOR_ST	O95817	BAG3	P42345	MTOR	S564	A557T	557	Missense	distal	-7	no	12.763	13.654	EPSD	TCGA;ICGC;COSMIC	6.822	Up-regulation
Atypical_PIKK_FRAP_MTOR_ST	O95817	BAG3	P42345	MTOR	T568	P562S	562	Missense	distal	-6	no	11.720	11.700	EPSD	TCGA;ICGC	6.822	Down-regulation
Atypical_PIKK_FRAP_MTOR_ST	Q9NQG5	RPRD1B	P42345	MTOR	S128	S128P	128	Missense	central	0	yes	9.238	0.000	EPSD	TCGA;ICGC;COSMIC	6.822	Loss
Atypical_PIKK_FRAP_MTOR_ST	Q9NQG5	RPRD1B	P42345	MTOR	S134	S128P	128	Missense	distal	-6	no	8.879	8.899	EPSD	TCGA;ICGC;COSMIC	6.822	Up-regulation
Atypical_PIKK_FRAP_MTOR_ST	Q9NQG5	RPRD1B	P42345	MTOR	S134	P137L	137	Missense	distal	3	no	8.879	6.624	EPSD	TCGA;ICGC;COSMIC	6.822	Loss
Atypical_PIKK_FRAP_MTOR_ST	Q9NQG5	RPRD1B	P42345	MTOR	S164	Q168R	168	Missense	distal	4	no	8.183	8.052	EPSD	TCGA;ICGC;COSMIC	6.822	Down-regulation
Atypical_PIKK_FRAP_MTOR_ST	Q9NQG5	RPRD1B	P42345	MTOR	S164	P170T	170	Missense	distal	6	no	8.183	7.299	EPSD	TCGA;ICGC;COSMIC	6.822	Down-regulation
Atypical_PIKK_FRAP_MTOR_ST	Q9NQG5	RPRD1B	P42345	MTOR	S166	Q168R	168	Missense	proximal	2	no	12.232	12.244	PhosphoSitePlus	TCGA;ICGC;COSMIC	6.822	Up-regulation
Atypical_PIKK_FRAP_MTOR_ST	Q9NQG5	RPRD1B	P42345	MTOR	S166	P170T	170	Missense	distal	4	no	12.232	12.555	PhosphoSitePlus	TCGA;ICGC;COSMIC	6.822	Up-regulation
Atypical_PIKK_FRAP_MTOR_ST	Q9UPY5	SLC7A11	P42345	MTOR	S51	T56I	56	Missense	distal	5	no	7.824	8.724	EPSD	TCGA;ICGC;COSMIC	6.822	Up-regulation
Atypical_PIKK_FRAP_MTOR_ST	Q86TB9	PATL1	P42345	MTOR	S184	P191S	191	Missense	distal	7	no	15.841	15.820	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	6.822	Down-regulation
Atypical_PIKK_FRAP_MTOR_ST	Q86TB9	PATL1	P42345	MTOR	S184	R188I	188	Missense	distal	4	no	15.841	15.978	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	6.822	Up-regulation
Atypical_PIKK_FRAP_MTOR_ST	Q86TB9	PATL1	P42345	MTOR	T194	P191S	191	Missense	distal	-3	no	11.270	11.702	EPSD	TCGA;ICGC;COSMIC	6.822	Up-regulation
Atypical_PIKK_FRAP_MTOR_ST	Q86TB9	PATL1	P42345	MTOR	T194	P196H	196	Missense	proximal	2	no	11.270	8.685	EPSD	TCGA;ICGC;COSMIC	6.822	Down-regulation
Atypical_PIKK_FRAP_MTOR_ST	Q86TB9	PATL1	P42345	MTOR	T194	R188I	188	Missense	distal	-6	no	11.270	10.603	EPSD	TCGA;ICGC;COSMIC	6.822	Down-regulation
Atypical_PIKK_FRAP_MTOR_ST	Q86TB9	PATL1	P42345	MTOR	S259	R263T	263	Missense	distal	4	no	10.583	11.224	EPSD	TCGA	6.822	Up-regulation
Atypical_PIKK_FRAP_MTOR_ST	Q86TB9	PATL1	P42345	MTOR	S259	P255S	255	Missense	distal	-4	no	10.583	10.712	EPSD	TCGA;ICGC;COSMIC	6.822	Up-regulation
Atypical_PIKK_FRAP_MTOR_ST	Q86TB9	PATL1	P42345	MTOR	S259	L261I	261	Missense	proximal	2	no	10.583	10.731	EPSD	TCGA;ICGC;COSMIC	6.822	Up-regulation
Atypical_PIKK_FRAP_MTOR_ST	Q86TB9	PATL1	P42345	MTOR	S278	S280N	280	Missense	proximal	2	no	10.419	9.017	EPSD	TCGA;ICGC;COSMIC	6.822	Down-regulation
Atypical_PIKK_FRAP_MTOR_ST	Q86TB9	PATL1	P42345	MTOR	S291	F288L	288	Missense	distal	-3	no	10.900	11.243	EPSD	TCGA;ICGC;COSMIC	6.822	Up-regulation
Atypical_PIKK_FRAP_MTOR_ST	Q86TB9	PATL1	P42345	MTOR	S546	L544I	544	Missense	proximal	-2	no	8.237	7.932	EPSD	TCGA;ICGC;COSMIC	6.822	Down-regulation
Atypical_PIKK_FRAP_MTOR_ST	Q86TB9	PATL1	P42345	MTOR	S546	E549K	549	Missense	distal	3	no	8.237	6.607	EPSD	TCGA;ICGC;COSMIC	6.822	Loss
Atypical_PIKK_FRAP_MTOR_ST	Q86TB9	PATL1	P42345	MTOR	S546	Y539D	539	Missense	distal	-7	no	8.237	8.570	EPSD	TCGA;ICGC;COSMIC	6.822	Up-regulation
Atypical_PIKK_FRAP_MTOR_ST	Q86TB9	PATL1	P42345	MTOR	S546	R542C	542	Missense	distal	-4	no	8.237	6.298	EPSD	TCGA;ICGC;COSMIC	6.822	Loss
Atypical_PIKK_FRAP_MTOR_ST	Q86TB9	PATL1	P42345	MTOR	S638	L642F	642	Missense	distal	4	no	6.504	6.900	EPSD	TCGA;ICGC;COSMIC	6.822	Gain
Atypical_PIKK_FRAP_MTOR_ST	Q86TB9	PATL1	P42345	MTOR	S738	I737M	737	Missense	proximal	-1	no	11.419	11.552	EPSD	TCGA	6.822	Up-regulation
Atypical_PIKK_FRAP_MTOR_ST	Q86TB9	PATL1	P42345	MTOR	S738	L733M	733	Missense	distal	-5	no	11.419	11.437	EPSD	TCGA;ICGC;COSMIC	6.822	Up-regulation
Atypical_PIKK_FRAP_MTOR_ST	Q86TB9	PATL1	P42345	MTOR	S738	I737L	737	Missense	proximal	-1	no	11.419	11.453	EPSD	TCGA;ICGC	6.822	Up-regulation
Atypical_PIKK_FRAP_MTOR_ST	Q13322	GRB10	P42345	MTOR	S104	R108T	108	Missense	distal	4	no	6.472	7.113	EPSD	TCGA;COSMIC	6.822	Gain
Atypical_PIKK_FRAP_MTOR_ST	Q13322	GRB10	P42345	MTOR	S134	P136A	136	Missense	proximal	2	no	10.264	9.006	EPSD	TCGA;COSMIC	6.822	Down-regulation
Atypical_PIKK_FRAP_MTOR_ST	Q13322	GRB10	P42345	MTOR	S134	Q128L	128	Missense	distal	-6	no	10.264	9.666	EPSD	TCGA;COSMIC	6.822	Down-regulation
Atypical_PIKK_FRAP_MTOR_ST	Q13322	GRB10	P42345	MTOR	S134	P141L	141	Missense	distal	7	no	10.264	11.220	EPSD	TCGA;COSMIC	6.822	Up-regulation
Atypical_PIKK_FRAP_MTOR_ST	Q13322	GRB10	P42345	MTOR	T155	P161A	161	Missense	distal	6	no	10.158	9.537	EPSD;PhosphoSitePlus	TCGA;COSMIC	6.822	Down-regulation
Atypical_PIKK_FRAP_MTOR_ST	Q13322	GRB10	P42345	MTOR	T155	S158Y	158	Missense	distal	3	no	10.158	9.018	EPSD;PhosphoSitePlus	TCGA;COSMIC	6.822	Down-regulation
Atypical_PIKK_FRAP_MTOR_ST	Q13322	GRB10	P42345	MTOR	S418	T422M	422	Missense	distal	4	no	9.602	9.388	EPSD	TCGA;COSMIC	6.822	Down-regulation
Atypical_PIKK_FRAP_MTOR_ST	Q13322	GRB10	P42345	MTOR	S418	S421L	421	Missense	distal	3	no	9.602	7.334	EPSD	TCGA;COSMIC;CCLE	6.822	Down-regulation
Atypical_PIKK_FRAP_MTOR_ST	Q13322	GRB10	P42345	MTOR	S418	R425H	425	Missense	distal	7	no	9.602	9.445	EPSD	TCGA;COSMIC	6.822	Down-regulation
Atypical_PIKK_FRAP_MTOR_ST	Q13322	GRB10	P42345	MTOR	S428	T422M	422	Missense	distal	-6	no	8.085	8.155	PhosphoSitePlus;EPSD	TCGA;COSMIC	6.822	Up-regulation
Atypical_PIKK_FRAP_MTOR_ST	Q13322	GRB10	P42345	MTOR	S428	S431C	431	Missense	distal	3	no	8.085	5.317	PhosphoSitePlus;EPSD	TCGA;COSMIC	6.822	Loss
Atypical_PIKK_FRAP_MTOR_ST	Q13322	GRB10	P42345	MTOR	S428	S421L	421	Missense	distal	-7	no	8.085	7.515	PhosphoSitePlus;EPSD	TCGA;COSMIC;CCLE	6.822	Down-regulation
Atypical_PIKK_FRAP_MTOR_ST	Q13322	GRB10	P42345	MTOR	S428	R425H	425	Missense	distal	-3	no	8.085	7.338	PhosphoSitePlus;EPSD	TCGA;COSMIC	6.822	Down-regulation
Atypical_PIKK_FRAP_MTOR_ST	Q13322	GRB10	P42345	MTOR	S428	E429D	429	Missense	proximal	1	no	8.085	7.249	PhosphoSitePlus;EPSD	TCGA	6.822	Down-regulation
Atypical_PIKK_FRAP_MTOR_ST	Q13322	GRB10	P42345	MTOR	S476	I471V	471	Missense	distal	-5	no	11.572	11.445	EPSD;PhosphoSitePlus	TCGA;COSMIC	6.822	Down-regulation
Atypical_PIKK_FRAP_MTOR_ST	Q13322	GRB10	P42345	MTOR	S476	G473C	473	Missense	distal	-3	no	11.572	10.834	EPSD;PhosphoSitePlus	TCGA;COSMIC	6.822	Down-regulation
Atypical_PIKK_FRAP_MTOR_ST	Q13322	GRB10	P42345	MTOR	S476	P480L	480	Missense	distal	4	no	11.572	11.188	EPSD;PhosphoSitePlus	TCGA;COSMIC	6.822	Down-regulation
Atypical_PIKK_FRAP_MTOR_ST	Q13322	GRB10	P42345	MTOR	S476	S476I	476	Missense	central	0	yes	11.572	0.000	EPSD;PhosphoSitePlus	TCGA;COSMIC	6.822	Loss
Atypical_PIKK_FRAP_MTOR_ST	O96018	APBA3	P42345	MTOR	S9	G12E	12	Missense	distal	3	no	9.984	9.168	EPSD	TCGA;ICGC;COSMIC	6.822	Down-regulation
Atypical_PIKK_FRAP_MTOR_ST	O96018	APBA3	P42345	MTOR	S9	S11L	11	Missense	proximal	2	no	9.984	9.789	EPSD	TCGA;ICGC;COSMIC;GDSC;CCLE	6.822	Down-regulation
Atypical_PIKK_FRAP_MTOR_ST	P31749	AKT1	P42345	MTOR	T92	R96W	96	Missense	distal	4	no	7.076	7.238	EPSD	TCGA;ICGC;COSMIC	6.822	Up-regulation
Atypical_PIKK_FRAP_MTOR_ST	P31749	AKT1	P42345	MTOR	T92	P93S	93	Missense	proximal	1	no	7.076	-1.448	EPSD	TCGA;ICGC;COSMIC	6.822	Loss
Atypical_PIKK_FRAP_MTOR_ST	P31749	AKT1	P42345	MTOR	S124	R121W	121	Missense	distal	-3	no	14.445	14.229	EPSD	TCGA;ICGC;COSMIC	6.822	Down-regulation
Atypical_PIKK_FRAP_MTOR_ST	P31749	AKT1	P42345	MTOR	S124	A131T	131	Missense	distal	7	no	14.445	13.924	EPSD	TCGA;ICGC;COSMIC	6.822	Down-regulation
Atypical_PIKK_FRAP_MTOR_ST	P31749	AKT1	P42345	MTOR	T312	G311D	311	Missense	proximal	-1	no	10.450	10.395	EPSD	TCGA;ICGC;COSMIC;GDSC;CCLE	6.822	Down-regulation
Atypical_PIKK_FRAP_MTOR_ST	P31749	AKT1	P42345	MTOR	S422	Y417C	417	Missense	distal	-5	no	10.195	9.968	EPSD	TCGA;ICGC;COSMIC	6.822	Down-regulation
Atypical_PIKK_FRAP_MTOR_ST	P31749	AKT1	P42345	MTOR	S422	P423T	423	Missense	proximal	1	no	10.195	3.924	EPSD	TCGA;ICGC	6.822	Loss
Atypical_PIKK_FRAP_MTOR_ST	P31749	AKT1	P42345	MTOR	S422	E418K	418	Missense	distal	-4	no	10.195	9.897	EPSD	TCGA;ICGC	6.822	Down-regulation
Atypical_PIKK_FRAP_MTOR_ST	P31749	AKT1	P42345	MTOR	T450	I447V	447	Missense	distal	-3	no	13.470	13.171	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	6.822	Down-regulation
Atypical_PIKK_FRAP_MTOR_ST	P31749	AKT1	P42345	MTOR	S473	S475L	475	Missense	proximal	2	no	13.336	13.141	PhosphoSitePlus;EPSD	TCGA;ICGC;COSMIC	6.822	Down-regulation
Atypical_PIKK_FRAP_MTOR_ST	P31749	AKT1	P42345	MTOR	S477	S475L	475	Missense	proximal	-2	no	8.451	8.317	EPSD	TCGA;ICGC;COSMIC	6.822	Down-regulation
Atypical_PIKK_FRAP_MTOR_ST	Q96F24	NRBF2	P42345	MTOR	S120	E124D	124	Missense	distal	4	no	8.445	8.606	PhosphoSitePlus;EPSD	TCGA;COSMIC	6.822	Up-regulation
Atypical_PIKK_FRAP_MTOR_ST	Q96F24	NRBF2	P42345	MTOR	S268	P272L	272	Missense	distal	4	no	11.864	11.480	EPSD	TCGA;COSMIC	6.822	Down-regulation
Atypical_PIKK_FRAP_MTOR_ST	Q96F24	NRBF2	P42345	MTOR	S268	S268F	268	Missense	central	0	yes	11.864	0.000	EPSD	TCGA;COSMIC	6.822	Loss
Atypical_PIKK_FRAP_MTOR_ST	Q96F24	NRBF2	P42345	MTOR	S268	P263S	263	Missense	distal	-5	no	11.864	11.816	EPSD	TCGA;COSMIC	6.822	Down-regulation
Atypical_PIKK_FRAP_MTOR_ST	Q8NHG8	ZNRF2	P42345	MTOR	S145	G144D	144	Missense	proximal	-1	no	9.832	9.777	PhosphoSitePlus	TCGA;ICGC	6.822	Down-regulation
Atypical_PIKK_FRAP_MTOR_ST	Q8NHG8	ZNRF2	P42345	MTOR	S151	G144D	144	Missense	distal	-7	no	7.603	8.410	EPSD	TCGA;ICGC	6.822	Up-regulation
Atypical_PIKK_FRAP_MTOR_ST	P62753	RPS6	P42345	MTOR	S236	K230N	230	Missense	distal	-6	no	9.910	9.454	PhosphoSitePlus;EPSD	TCGA;ICGC;COSMIC	6.822	Down-regulation
Atypical_PIKK_FRAP_MTOR_ST	P62753	RPS6	P42345	MTOR	S236	S236C	236	Missense	central	0	yes	9.910	0.000	PhosphoSitePlus;EPSD	TCGA;ICGC;COSMIC	6.822	Loss
Atypical_PIKK_FRAP_MTOR_ST	P62753	RPS6	P42345	MTOR	S236	R232H	232	Missense	distal	-4	no	9.910	8.717	PhosphoSitePlus;EPSD	TCGA;ICGC;COSMIC	6.822	Down-regulation
Atypical_PIKK_FRAP_MTOR_ST	P62753	RPS6	P42345	MTOR	S236	R233I	233	Missense	distal	-3	no	9.910	9.999	PhosphoSitePlus;EPSD	TCGA;ICGC;COSMIC	6.822	Up-regulation
Atypical_PIKK_FRAP_MTOR_ST	P62753	RPS6	P42345	MTOR	S236	R232C	232	Missense	distal	-4	no	9.910	7.970	PhosphoSitePlus;EPSD	TCGA;ICGC;COSMIC	6.822	Down-regulation
Atypical_PIKK_FRAP_MTOR_ST	P62753	RPS6	P42345	MTOR	S240	S236C	236	Missense	distal	-4	no	8.612	6.787	EPSD	TCGA;ICGC;COSMIC	6.822	Loss
Atypical_PIKK_FRAP_MTOR_ST	P62753	RPS6	P42345	MTOR	S240	R233I	233	Missense	distal	-7	no	8.612	8.365	EPSD	TCGA;ICGC;COSMIC	6.822	Down-regulation
Atypical_PIKK_FRAP_MTOR_ST	P62753	RPS6	P42345	MTOR	T241	S236C	236	Missense	distal	-5	no	8.773	9.039	EPSD	TCGA;ICGC;COSMIC	6.822	Up-regulation
Atypical_PIKK_FRAP_MTOR_ST	P62753	RPS6	P42345	MTOR	T241	Q248H	248	Missense	distal	7	no	8.773	9.015	EPSD	TCGA;ICGC;COSMIC	6.822	Up-regulation
Atypical_PIKK_FRAP_MTOR_ST	P62753	RPS6	P42345	MTOR	S244	Q248H	248	Missense	distal	4	no	10.028	9.637	EPSD	TCGA;ICGC;COSMIC	6.822	Down-regulation
Atypical_PIKK_FRAP_MTOR_ST	O95747	OXSR1	P42345	MTOR	T185	R179Q	179	Missense	distal	-6	no	7.324	7.060	EPSD	TCGA;ICGC;COSMIC	6.822	Down-regulation
Atypical_PIKK_FRAP_MTOR_ST	O95747	OXSR1	P42345	MTOR	T185	V187A	187	Missense	proximal	2	no	7.324	6.576	EPSD	TCGA;ICGC;COSMIC	6.822	Loss
Atypical_PIKK_FRAP_MTOR_ST	O95747	OXSR1	P42345	MTOR	T185	G188D	188	Missense	distal	3	no	7.324	5.582	EPSD	TCGA;ICGC;COSMIC	6.822	Loss
Atypical_PIKK_FRAP_MTOR_ST	O95747	OXSR1	P42345	MTOR	T185	V182A	182	Missense	distal	-3	no	7.324	6.694	EPSD	TCGA;ICGC;COSMIC	6.822	Loss
Atypical_PIKK_FRAP_MTOR_ST	O95747	OXSR1	P42345	MTOR	S347	D340N	340	Missense	distal	-7	no	7.853	7.417	EPSD	TCGA;ICGC;COSMIC	6.822	Down-regulation
Atypical_PIKK_FRAP_MTOR_ST	O95747	OXSR1	P42345	MTOR	S347	F343L	343	Missense	distal	-4	no	7.853	7.513	EPSD	TCGA;ICGC;COSMIC	6.822	Down-regulation
Atypical_PIKK_FRAP_MTOR_ST	Q9H1K1	ISCU	P42345	MTOR	S51	S56F	56	Missense	distal	5	no	6.240	6.827	EPSD	TCGA;ICGC;COSMIC	6.822	Gain
Atypical_PIKK_FRAP_MTOR_ST	Q9BRS8	LARP6	P42345	MTOR	S228	R231W	231	Missense	distal	3	no	7.134	5.374	EPSD	TCGA;ICGC;COSMIC	6.822	Loss
Atypical_PIKK_FRAP_MTOR_ST	Q9BRS8	LARP6	P42345	MTOR	S228	R231Q	231	Missense	distal	3	no	7.134	5.868	EPSD	TCGA;ICGC;COSMIC	6.822	Loss
Atypical_PIKK_FRAP_MTOR_ST	Q9BRS8	LARP6	P42345	MTOR	S228	G222R	222	Missense	distal	-6	no	7.134	7.119	EPSD	TCGA;ICGC	6.822	Down-regulation
Atypical_PIKK_FRAP_MTOR_ST	Q9BRS8	LARP6	P42345	MTOR	S348	R353Q	353	Missense	distal	5	no	10.757	9.950	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	6.822	Down-regulation
Atypical_PIKK_FRAP_MTOR_ST	Q9BRS8	LARP6	P42345	MTOR	S348	P342L	342	Missense	distal	-6	no	10.757	9.982	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	6.822	Down-regulation
Atypical_PIKK_FRAP_MTOR_ST	Q9BRS8	LARP6	P42345	MTOR	S362	L369I	369	Missense	distal	7	no	12.747	12.145	EPSD	TCGA;ICGC;COSMIC	6.822	Down-regulation
Atypical_PIKK_FRAP_MTOR_ST	Q9BRS8	LARP6	P42345	MTOR	S372	P377S	377	Missense	distal	5	no	11.055	10.941	EPSD	TCGA;ICGC;COSMIC	6.822	Down-regulation
Atypical_PIKK_FRAP_MTOR_ST	Q9BRS8	LARP6	P42345	MTOR	S372	L369I	369	Missense	distal	-3	no	11.055	11.075	EPSD	TCGA;ICGC;COSMIC	6.822	Up-regulation
Atypical_PIKK_FRAP_MTOR_ST	Q9BRS8	LARP6	P42345	MTOR	S376	P377S	377	Missense	proximal	1	no	8.196	-0.328	EPSD	TCGA;ICGC;COSMIC	6.822	Loss
Atypical_PIKK_FRAP_MTOR_ST	Q9BRS8	LARP6	P42345	MTOR	S376	L369I	369	Missense	distal	-7	no	8.196	7.760	EPSD	TCGA;ICGC;COSMIC	6.822	Down-regulation
Atypical_PIKK_FRAP_MTOR_ST	Q9BRS8	LARP6	P42345	MTOR	S384	P377S	377	Missense	distal	-7	no	10.186	10.623	EPSD	TCGA;ICGC;COSMIC	6.822	Up-regulation
Atypical_PIKK_FRAP_MTOR_ST	Q9BRS8	LARP6	P42345	MTOR	S384	R389C	389	Missense	distal	5	no	10.186	9.970	EPSD	TCGA;ICGC;COSMIC	6.822	Down-regulation
Atypical_PIKK_FRAP_MTOR_ST	Q9BRS8	LARP6	P42345	MTOR	S396	V392I	392	Missense	distal	-4	no	12.077	11.835	EPSD	TCGA;ICGC;COSMIC	6.822	Down-regulation
Atypical_PIKK_FRAP_MTOR_ST	Q9BRS8	LARP6	P42345	MTOR	S396	P397S	397	Missense	proximal	1	no	12.077	3.553	EPSD	TCGA;ICGC;COSMIC	6.822	Loss
Atypical_PIKK_FRAP_MTOR_ST	Q9BRS8	LARP6	P42345	MTOR	S396	S393F	393	Missense	distal	-3	no	12.077	12.148	EPSD	TCGA;ICGC;COSMIC	6.822	Up-regulation
Atypical_PIKK_FRAP_MTOR_ST	Q9BRS8	LARP6	P42345	MTOR	S396	R389C	389	Missense	distal	-7	no	12.077	10.982	EPSD	TCGA;ICGC;COSMIC	6.822	Down-regulation
Atypical_PIKK_FRAP_MTOR_ST	Q9BRS8	LARP6	P42345	MTOR	S409	L404P	404	Missense	distal	-5	no	8.698	8.770	PhosphoSitePlus;EPSD	TCGA;ICGC	6.822	Up-regulation
Atypical_PIKK_FRAP_MTOR_ST	Q9BRS8	LARP6	P42345	MTOR	S424	V425I	425	Missense	proximal	1	no	7.929	9.593	EPSD	TCGA;ICGC;COSMIC	6.822	Up-regulation
Atypical_PIKK_FRAP_MTOR_ST	Q9BRS8	LARP6	P42345	MTOR	S424	M417V	417	Missense	distal	-7	no	7.929	7.789	EPSD	TCGA;ICGC;COSMIC	6.822	Down-regulation
Atypical_PIKK_FRAP_MTOR_ST	Q9BRS8	LARP6	P42345	MTOR	S424	G429R	429	Missense	distal	5	no	7.929	8.259	EPSD	TCGA;ICGC;COSMIC	6.822	Up-regulation
Atypical_PIKK_FRAP_MTOR_ST	Q9BRS8	LARP6	P42345	MTOR	S430	V425I	425	Missense	distal	-5	no	7.158	7.286	EPSD	TCGA;ICGC;COSMIC	6.822	Up-regulation
Atypical_PIKK_FRAP_MTOR_ST	Q9BRS8	LARP6	P42345	MTOR	S430	R436H	436	Missense	distal	6	no	7.158	7.474	EPSD	TCGA;ICGC	6.822	Up-regulation
Atypical_PIKK_FRAP_MTOR_ST	Q9BRS8	LARP6	P42345	MTOR	S430	R435W	435	Missense	distal	5	no	7.158	6.175	EPSD	TCGA;ICGC;COSMIC	6.822	Loss
Atypical_PIKK_FRAP_MTOR_ST	Q9BRS8	LARP6	P42345	MTOR	S430	R437H	437	Missense	distal	7	no	7.158	7.001	EPSD	TCGA;ICGC;COSMIC	6.822	Down-regulation
Atypical_PIKK_FRAP_MTOR_ST	Q9BRS8	LARP6	P42345	MTOR	S430	R436C	436	Missense	distal	6	no	7.158	7.285	EPSD	TCGA;ICGC;COSMIC;GDSC;CCLE	6.822	Up-regulation
Atypical_PIKK_FRAP_MTOR_ST	Q9BRS8	LARP6	P42345	MTOR	S430	G429R	429	Missense	proximal	-1	no	7.158	7.003	EPSD	TCGA;ICGC;COSMIC	6.822	Down-regulation
Atypical_PIKK_FRAP_MTOR_ST	Q9BRS8	LARP6	P42345	MTOR	S451	G449S	449	Missense	proximal	-2	no	8.920	8.190	EPSD	TCGA;ICGC;COSMIC	6.822	Down-regulation
Atypical_PIKK_FRAP_MTOR_ST	Q9BRS8	LARP6	P42345	MTOR	S451	P452L	452	Missense	proximal	1	no	8.920	2.951	EPSD	TCGA;ICGC;COSMIC	6.822	Loss
Atypical_PIKK_FRAP_MTOR_ST	Q9BRS8	LARP6	P42345	MTOR	S451	P448L	448	Missense	distal	-3	no	8.920	9.767	EPSD	TCGA;ICGC;COSMIC	6.822	Up-regulation
Atypical_PIKK_FRAP_MTOR_ST	Q9BRS8	LARP6	P42345	MTOR	S451	P448S	448	Missense	distal	-3	no	8.920	9.352	EPSD	TCGA;ICGC;COSMIC	6.822	Up-regulation
Atypical_PIKK_FRAP_MTOR_ST	Q9BRS8	LARP6	P42345	MTOR	S451	Q444H	444	Missense	distal	-7	no	8.920	8.648	EPSD	TCGA;ICGC;COSMIC	6.822	Down-regulation
Atypical_PIKK_FRAP_MTOR_ST	P26358	DNMT1	P42345	MTOR	S714	M712I	712	Missense	proximal	-2	no	10.634	10.718	PhosphoSitePlus	TCGA;ICGC;COSMIC	6.822	Up-regulation
Atypical_PIKK_FRAP_MTOR_ST	P01106	MYC	P42345	MTOR	S161	S161L	161	Missense	central	0	yes	8.230	0.000	EPSD	TCGA;ICGC;COSMIC	6.822	Loss
Atypical_PIKK_FRAP_MTOR_ST	P01106	MYC	P42345	MTOR	S204	S207L	207	Missense	distal	3	no	7.797	5.529	EPSD	TCGA;ICGC;COSMIC	6.822	Loss
Atypical_PIKK_FRAP_MTOR_ST	P01106	MYC	P42345	MTOR	S344	K341R	341	Missense	distal	-3	no	11.935	12.649	EPSD	TCGA;ICGC;COSMIC	6.822	Up-regulation
Atypical_PIKK_FRAP_MTOR_ST	Q9BPZ7	MAPKAP1	P42345	MTOR	S84	R89T	89	Missense	distal	5	no	8.791	7.402	EPSD	TCGA;ICGC;COSMIC	6.822	Down-regulation
Atypical_PIKK_FRAP_MTOR_ST	Q9BPZ7	MAPKAP1	P42345	MTOR	S84	D77Y	77	Missense	distal	-7	no	8.791	8.458	EPSD	TCGA;ICGC;COSMIC	6.822	Down-regulation
Atypical_PIKK_FRAP_MTOR_ST	Q9BPZ7	MAPKAP1	P42345	MTOR	S84	R81T	81	Missense	distal	-3	no	8.791	8.006	EPSD	TCGA;ICGC;COSMIC	6.822	Down-regulation
Atypical_PIKK_FRAP_MTOR_ST	Q9BPZ7	MAPKAP1	P42345	MTOR	S84	S84L	84	Missense	central	0	yes	8.791	0.000	EPSD	TCGA;ICGC;COSMIC	6.822	Loss
Atypical_PIKK_FRAP_MTOR_ST	Q9BPZ7	MAPKAP1	P42345	MTOR	S84	R83C	83	Missense	proximal	-1	no	8.791	8.964	EPSD	TCGA;ICGC;COSMIC	6.822	Up-regulation
Atypical_PIKK_FRAP_MTOR_ST	Q9BPZ7	MAPKAP1	P42345	MTOR	S84	R89I	89	Missense	distal	5	no	8.791	8.302	EPSD	TCGA;ICGC;COSMIC	6.822	Down-regulation
Atypical_PIKK_FRAP_MTOR_ST	Q9BPZ7	MAPKAP1	P42345	MTOR	T194	D188N	188	Missense	distal	-6	no	6.829	6.037	EPSD	TCGA;ICGC;COSMIC	6.822	Loss
Atypical_PIKK_FRAP_MTOR_ST	Q9BPZ7	MAPKAP1	P42345	MTOR	T194	A201T	201	Missense	distal	7	no	6.829	6.308	EPSD	TCGA;COSMIC	6.822	Loss
Atypical_PIKK_FRAP_MTOR_ST	Q9BPZ7	MAPKAP1	P42345	MTOR	T194	T194I	194	Missense	central	0	yes	6.829	0.000	EPSD	TCGA;COSMIC	6.822	Loss
Atypical_PIKK_FRAP_MTOR_ST	Q9BPZ7	MAPKAP1	P42345	MTOR	S270	E266K	266	Missense	distal	-4	no	9.225	8.927	EPSD	TCGA;COSMIC	6.822	Down-regulation
Atypical_PIKK_FRAP_MTOR_ST	Q9BPZ7	MAPKAP1	P42345	MTOR	S510	R503T	503	Missense	distal	-7	no	8.195	9.005	EPSD	TCGA;COSMIC	6.822	Up-regulation
Atypical_PIKK_FRAP_MTOR_ST	Q9BPZ7	MAPKAP1	P42345	MTOR	S510	T509M	509	Missense	proximal	-1	no	8.195	8.146	EPSD	TCGA;COSMIC	6.822	Down-regulation
Atypical_PIKK_FRAP_MTOR_ST	Q9BPZ7	MAPKAP1	P42345	MTOR	S510	K517N	517	Missense	distal	7	no	8.195	9.147	EPSD	TCGA;COSMIC	6.822	Up-regulation
Atypical_PIKK_FRAP_MTOR_ST	Q9BPZ7	MAPKAP1	P42345	MTOR	S510	R508H	508	Missense	proximal	-2	no	8.195	7.965	EPSD	TCGA;COSMIC	6.822	Down-regulation
Atypical_PIKK_FRAP_MTOR_ST	Q9BPZ7	MAPKAP1	P42345	MTOR	S510	R508C	508	Missense	proximal	-2	no	8.195	8.473	EPSD	TCGA;COSMIC	6.822	Up-regulation
Atypical_PIKK_FRAP_MTOR_ST	Q9Y6W6	DUSP10	P42345	MTOR	S224	D223N	223	Missense	proximal	-1	no	9.530	9.411	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	6.822	Down-regulation
Atypical_PIKK_FRAP_MTOR_ST	Q9Y6W6	DUSP10	P42345	MTOR	S224	S217F	217	Missense	distal	-7	no	9.530	9.305	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	6.822	Down-regulation
Atypical_PIKK_FRAP_MTOR_ST	Q9Y6W6	DUSP10	P42345	MTOR	S230	D223N	223	Missense	distal	-7	no	7.943	7.508	PhosphoSitePlus;EPSD	TCGA;ICGC;COSMIC	6.822	Down-regulation
Atypical_PIKK_FRAP_MTOR_ST	Q9Y6W6	DUSP10	P42345	MTOR	S230	D237G	237	Missense	distal	7	no	7.943	7.765	PhosphoSitePlus;EPSD	TCGA;ICGC;COSMIC	6.822	Down-regulation
Atypical_PIKK_FRAP_MTOR_ST	Q9Y6W6	DUSP10	P42345	MTOR	S230	I234M	234	Missense	distal	4	no	7.943	8.232	PhosphoSitePlus;EPSD	TCGA;ICGC;COSMIC	6.822	Up-regulation
Atypical_PIKK_FRAP_MTOR_ST	Q8TBX8	PIP4K2C	P42345	MTOR	S324	P319A	319	Missense	distal	-5	no	10.254	10.233	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	6.822	Down-regulation
Atypical_PIKK_FRAP_MTOR_ST	Q8TBX8	PIP4K2C	P42345	MTOR	S324	G323C	323	Missense	proximal	-1	no	10.254	10.272	EPSD;PhosphoSitePlus	TCGA;ICGC	6.822	Up-regulation
Atypical_PIKK_FRAP_MTOR_ST	Q8TBX8	PIP4K2C	P42345	MTOR	S328	G333R	333	Missense	distal	5	no	10.768	11.098	PhosphoSitePlus;EPSD	TCGA;ICGC;COSMIC	6.822	Up-regulation
Atypical_PIKK_FRAP_MTOR_ST	Q8TBX8	PIP4K2C	P42345	MTOR	S328	G323C	323	Missense	distal	-5	no	10.768	10.966	PhosphoSitePlus;EPSD	TCGA;ICGC	6.822	Up-regulation
Atypical_PIKK_FRAP_MTOR_ST	Q9C0C7	AMBRA1	P42345	MTOR	S52	S55Y	55	Missense	distal	3	no	12.532	11.392	PhosphoSitePlus	TCGA;ICGC;COSMIC	6.822	Down-regulation
Atypical_PIKK_FRAP_MTOR_ST	Q9C0C7	AMBRA1	P42345	MTOR	S636	A638T	638	Missense	proximal	2	no	6.832	7.536	EPSD	TCGA;COSMIC	6.822	Up-regulation
Atypical_PIKK_FRAP_MTOR_ST	Q00613	HSF1	P42345	MTOR	S123	E128K	128	Missense	distal	5	no	12.025	12.080	EPSD	TCGA;COSMIC	6.822	Up-regulation
Atypical_PIKK_FRAP_MTOR_ST	Q00613	HSF1	P42345	MTOR	S123	I130V	130	Missense	distal	7	no	12.025	12.164	EPSD	TCGA;COSMIC	6.822	Up-regulation
Atypical_PIKK_FRAP_MTOR_ST	Q00613	HSF1	P42345	MTOR	S123	L125M	125	Missense	proximal	2	no	12.025	10.786	EPSD	TCGA;COSMIC	6.822	Down-regulation
Atypical_PIKK_FRAP_MTOR_ST	Q00613	HSF1	P42345	MTOR	S136	R133H	133	Missense	distal	-3	no	11.475	10.728	EPSD	TCGA;COSMIC	6.822	Down-regulation
Atypical_PIKK_FRAP_MTOR_ST	Q00613	HSF1	P42345	MTOR	S136	I130V	130	Missense	distal	-6	no	11.475	11.412	EPSD	TCGA;COSMIC	6.822	Down-regulation
Atypical_PIKK_FRAP_MTOR_ST	Q00613	HSF1	P42345	MTOR	S244	S250C	250	Missense	distal	6	no	9.770	8.075	EPSD	TCGA;COSMIC	6.822	Down-regulation
Atypical_PIKK_FRAP_MTOR_ST	Q00613	HSF1	P42345	MTOR	S275	P276L	276	Missense	proximal	1	no	8.306	2.336	EPSD	TCGA;COSMIC	6.822	Loss
Atypical_PIKK_FRAP_MTOR_ST	Q00613	HSF1	P42345	MTOR	S275	M277V	277	Missense	proximal	2	no	8.306	9.724	EPSD	TCGA;COSMIC	6.822	Up-regulation
Atypical_PIKK_FRAP_MTOR_ST	Q00613	HSF1	P42345	MTOR	S279	P276L	276	Missense	distal	-3	no	10.095	10.943	EPSD	TCGA;COSMIC	6.822	Up-regulation
Atypical_PIKK_FRAP_MTOR_ST	Q00613	HSF1	P42345	MTOR	S279	E286K	286	Missense	distal	7	no	10.095	10.192	EPSD	TCGA;COSMIC	6.822	Up-regulation
Atypical_PIKK_FRAP_MTOR_ST	Q00613	HSF1	P42345	MTOR	S279	M277V	277	Missense	proximal	-2	no	10.095	10.702	EPSD	TCGA;COSMIC	6.822	Up-regulation
Atypical_PIKK_FRAP_MTOR_ST	Q00613	HSF1	P42345	MTOR	S292	R296C	296	Missense	distal	4	no	10.886	10.673	EPSD	TCGA;COSMIC	6.822	Down-regulation
Atypical_PIKK_FRAP_MTOR_ST	Q00613	HSF1	P42345	MTOR	S292	P288L	288	Missense	distal	-4	no	10.886	10.700	EPSD	TCGA;COSMIC	6.822	Down-regulation
Atypical_PIKK_FRAP_MTOR_ST	Q00613	HSF1	P42345	MTOR	S292	E286K	286	Missense	distal	-6	no	10.886	10.740	EPSD	TCGA;COSMIC	6.822	Down-regulation
Atypical_PIKK_FRAP_MTOR_ST	Q00613	HSF1	P42345	MTOR	S307	E300Q	300	Missense	distal	-7	no	9.596	9.165	EPSD	TCGA	6.822	Down-regulation
Atypical_PIKK_FRAP_MTOR_ST	Q00613	HSF1	P42345	MTOR	S314	R317H	317	Missense	distal	3	no	13.184	13.354	EPSD	TCGA;COSMIC	6.822	Up-regulation
Atypical_PIKK_FRAP_MTOR_ST	Q00613	HSF1	P42345	MTOR	S314	S320F	320	Missense	distal	6	no	13.184	12.609	EPSD	TCGA;COSMIC	6.822	Down-regulation
Atypical_PIKK_FRAP_MTOR_ST	Q00613	HSF1	P42345	MTOR	S320	P327L	327	Missense	distal	7	no	6.766	7.722	EPSD	TCGA	6.822	Gain
Atypical_PIKK_FRAP_MTOR_ST	Q00613	HSF1	P42345	MTOR	S326	D332Y	332	Missense	distal	6	no	11.446	10.297	PhosphoSitePlus	TCGA;COSMIC	6.822	Down-regulation
Atypical_PIKK_FRAP_MTOR_ST	Q00613	HSF1	P42345	MTOR	S326	T323I	323	Missense	distal	-3	no	11.446	12.321	PhosphoSitePlus	TCGA;COSMIC	6.822	Up-regulation
Atypical_PIKK_FRAP_MTOR_ST	Q00613	HSF1	P42345	MTOR	S326	S320F	320	Missense	distal	-6	no	11.446	10.971	PhosphoSitePlus	TCGA;COSMIC	6.822	Down-regulation
Atypical_PIKK_FRAP_MTOR_ST	Q00613	HSF1	P42345	MTOR	S326	A329T	329	Missense	distal	3	no	11.446	9.984	PhosphoSitePlus	TCGA;COSMIC	6.822	Down-regulation
Atypical_PIKK_FRAP_MTOR_ST	Q00613	HSF1	P42345	MTOR	S326	S333F	333	Missense	distal	7	no	11.446	12.026	PhosphoSitePlus	TCGA;COSMIC	6.822	Up-regulation
Atypical_PIKK_FRAP_MTOR_ST	Q00613	HSF1	P42345	MTOR	S326	P327L	327	Missense	proximal	1	no	11.446	5.477	PhosphoSitePlus	TCGA	6.822	Loss
Atypical_PIKK_FRAP_MTOR_ST	Q00613	HSF1	P42345	MTOR	S363	P364S	364	Missense	proximal	1	no	8.232	-0.292	EPSD	TCGA;COSMIC	6.822	Loss
Atypical_PIKK_FRAP_MTOR_ST	Q00613	HSF1	P42345	MTOR	T369	P364S	364	Missense	distal	-5	no	14.012	13.964	EPSD	TCGA;COSMIC	6.822	Down-regulation
Atypical_PIKK_FRAP_MTOR_ST	Q00613	HSF1	P42345	MTOR	S419	P420L	420	Missense	proximal	1	no	14.113	8.144	EPSD	TCGA;ICGC;COSMIC	6.822	Down-regulation
Atypical_PIKK_FRAP_MTOR_ST	Q00613	HSF1	P42345	MTOR	S419	P425S	425	Missense	distal	6	no	14.113	14.143	EPSD	TCGA;ICGC;COSMIC	6.822	Up-regulation
Atypical_PIKK_FRAP_MTOR_ST	Q00613	HSF1	P42345	MTOR	S458	E453K	453	Missense	distal	-5	no	6.608	6.900	EPSD	TCGA;COSMIC	6.822	Gain
Atypical_PIKK_FRAP_MTOR_ST	Q00613	HSF1	P42345	MTOR	S513	A507V	507	Missense	distal	-6	no	9.925	9.640	EPSD	TCGA;ICGC;COSMIC	6.822	Down-regulation
Atypical_PIKK_FRAP_MTOR_ST	Q5T4S7	UBR4	P42345	MTOR	S178	P179S	179	Missense	proximal	1	no	11.189	2.665	EPSD	TCGA;ICGC;COSMIC	6.822	Loss
Atypical_PIKK_FRAP_MTOR_ST	Q5T4S7	UBR4	P42345	MTOR	S372	A374V	374	Missense	proximal	2	no	10.830	11.577	EPSD	TCGA;ICGC;COSMIC	6.822	Up-regulation
Atypical_PIKK_FRAP_MTOR_ST	Q5T4S7	UBR4	P42345	MTOR	S457	R450L	450	Missense	distal	-7	no	7.396	7.585	EPSD	TCGA;ICGC;COSMIC	6.822	Up-regulation
Atypical_PIKK_FRAP_MTOR_ST	Q5T4S7	UBR4	P42345	MTOR	S457	T451A	451	Missense	distal	-6	no	7.396	7.117	EPSD	TCGA;ICGC;COSMIC	6.822	Down-regulation
Atypical_PIKK_FRAP_MTOR_ST	Q5T4S7	UBR4	P42345	MTOR	S457	R450H	450	Missense	distal	-7	no	7.396	7.047	EPSD	TCGA;ICGC	6.822	Down-regulation
Atypical_PIKK_FRAP_MTOR_ST	Q5T4S7	UBR4	P42345	MTOR	S620	P613Q	613	Missense	distal	-7	no	8.757	8.357	EPSD	TCGA;ICGC;COSMIC	6.822	Down-regulation
Atypical_PIKK_FRAP_MTOR_ST	Q5T4S7	UBR4	P42345	MTOR	T905	R902Q	902	Missense	distal	-3	no	8.373	7.765	EPSD	TCGA;ICGC	6.822	Down-regulation
Atypical_PIKK_FRAP_MTOR_ST	Q5T4S7	UBR4	P42345	MTOR	S1601	C1597R	1597	Missense	distal	-4	no	6.702	8.642	EPSD	TCGA;ICGC;COSMIC	6.822	Gain
Atypical_PIKK_FRAP_MTOR_ST	Q5T4S7	UBR4	P42345	MTOR	S1652	D1653H	1653	Missense	proximal	1	no	6.917	-11.254	EPSD	TCGA;ICGC;COSMIC	6.822	Loss
Atypical_PIKK_FRAP_MTOR_ST	Q5T4S7	UBR4	P42345	MTOR	T1731	S1737C	1737	Missense	distal	6	no	8.291	6.595	EPSD	TCGA;ICGC	6.822	Loss
Atypical_PIKK_FRAP_MTOR_ST	Q5T4S7	UBR4	P42345	MTOR	S1762	R1757H	1757	Missense	distal	-5	no	7.527	7.531	EPSD	TCGA;ICGC;COSMIC	6.822	Up-regulation
Atypical_PIKK_FRAP_MTOR_ST	Q5T4S7	UBR4	P42345	MTOR	S1904	S1904C	1904	Missense	central	0	yes	10.006	0.000	EPSD	TCGA;ICGC;COSMIC	6.822	Loss
Atypical_PIKK_FRAP_MTOR_ST	Q5T4S7	UBR4	P42345	MTOR	S1904	R1908C	1908	Missense	distal	4	no	10.006	9.793	EPSD	TCGA;ICGC;COSMIC	6.822	Down-regulation
Atypical_PIKK_FRAP_MTOR_ST	Q5T4S7	UBR4	P42345	MTOR	S1904	R1909C	1909	Missense	distal	5	no	10.006	9.790	EPSD	TCGA;ICGC;COSMIC	6.822	Down-regulation
Atypical_PIKK_FRAP_MTOR_ST	Q5T4S7	UBR4	P42345	MTOR	T2140	S2137N	2137	Missense	distal	-3	no	6.518	7.068	EPSD	TCGA;ICGC;COSMIC	6.822	Gain
Atypical_PIKK_FRAP_MTOR_ST	Q5T4S7	UBR4	P42345	MTOR	S2264	K2267N	2267	Missense	distal	3	no	6.309	7.143	EPSD	TCGA;ICGC;COSMIC	6.822	Gain
Atypical_PIKK_FRAP_MTOR_ST	Q5T4S7	UBR4	P42345	MTOR	S2719	T2715P	2715	Missense	distal	-4	no	8.123	8.496	EPSD	TCGA;COSMIC	6.822	Up-regulation
Atypical_PIKK_FRAP_MTOR_ST	Q5T4S7	UBR4	P42345	MTOR	S2719	R2712K	2712	Missense	distal	-7	no	8.123	8.269	EPSD	TCGA	6.822	Up-regulation
Atypical_PIKK_FRAP_MTOR_ST	Q5T4S7	UBR4	P42345	MTOR	S2719	T2715A	2715	Missense	distal	-4	no	8.123	7.662	EPSD	TCGA	6.822	Down-regulation
Atypical_PIKK_FRAP_MTOR_ST	Q5T4S7	UBR4	P42345	MTOR	S2722	T2715P	2715	Missense	distal	-7	no	8.810	8.322	EPSD	TCGA;COSMIC	6.822	Down-regulation
Atypical_PIKK_FRAP_MTOR_ST	Q5T4S7	UBR4	P42345	MTOR	S2722	T2715A	2715	Missense	distal	-7	no	8.810	7.919	EPSD	TCGA	6.822	Down-regulation
Atypical_PIKK_FRAP_MTOR_ST	Q5T4S7	UBR4	P42345	MTOR	S2788	P2789L	2789	Missense	proximal	1	no	11.301	5.332	EPSD	TCGA;COSMIC	6.822	Loss
Atypical_PIKK_FRAP_MTOR_ST	Q5T4S7	UBR4	P42345	MTOR	S2788	G2785C	2785	Missense	distal	-3	no	11.301	10.563	EPSD	TCGA;COSMIC	6.822	Down-regulation
Atypical_PIKK_FRAP_MTOR_ST	Q5T4S7	UBR4	P42345	MTOR	S2852	Q2846R	2846	Missense	distal	-6	no	6.621	6.885	EPSD	TCGA;ICGC;COSMIC	6.822	Gain
Atypical_PIKK_FRAP_MTOR_ST	Q5T4S7	UBR4	P42345	MTOR	S2910	S2915R	2915	Missense	distal	5	no	7.401	8.394	EPSD	TCGA;COSMIC	6.822	Up-regulation
Atypical_PIKK_FRAP_MTOR_ST	Q5T4S7	UBR4	P42345	MTOR	S2910	R2914Q	2914	Missense	distal	4	no	7.401	7.533	EPSD	TCGA;COSMIC	6.822	Up-regulation
Atypical_PIKK_FRAP_MTOR_ST	Q5T4S7	UBR4	P42345	MTOR	S2910	E2908D	2908	Missense	proximal	-2	no	7.401	6.987	EPSD	TCGA;COSMIC	6.822	Down-regulation
Atypical_PIKK_FRAP_MTOR_ST	Q5T4S7	UBR4	P42345	MTOR	S2910	S2910N	2910	Missense	central	0	yes	7.401	0.000	EPSD	TCGA;COSMIC	6.822	Loss
Atypical_PIKK_FRAP_MTOR_ST	Q5T4S7	UBR4	P42345	MTOR	S2910	R2914W	2914	Missense	distal	4	no	7.401	7.563	EPSD	TCGA;COSMIC	6.822	Up-regulation
Atypical_PIKK_FRAP_MTOR_ST	Q5T4S7	UBR4	P42345	MTOR	S3254	A3258S	3258	Missense	distal	4	no	6.678	7.152	EPSD	TCGA	6.822	Gain
Atypical_PIKK_FRAP_MTOR_ST	Q5T4S7	UBR4	P42345	MTOR	S3316	E3313K	3313	Missense	distal	-3	no	11.730	11.735	EPSD	TCGA;COSMIC;GDSC;CCLE	6.822	Up-regulation
Atypical_PIKK_FRAP_MTOR_ST	Q5T4S7	UBR4	P42345	MTOR	S3316	G3314D	3314	Missense	proximal	-2	no	11.730	10.676	EPSD	TCGA;COSMIC	6.822	Down-regulation
Atypical_PIKK_FRAP_MTOR_ST	Q5T4S7	UBR4	P42345	MTOR	T4005	P4006S	4006	Missense	proximal	1	no	12.105	3.581	EPSD	TCGA;COSMIC	6.822	Loss
Atypical_PIKK_FRAP_MTOR_ST	Q5T4S7	UBR4	P42345	MTOR	T4005	L3998F	3998	Missense	distal	-7	no	12.105	12.450	EPSD	TCGA;COSMIC	6.822	Up-regulation
Atypical_PIKK_FRAP_MTOR_ST	Q5T4S7	UBR4	P42345	MTOR	S4117	R4111C	4111	Missense	distal	-6	no	11.895	12.022	EPSD	TCGA;COSMIC	6.822	Up-regulation
Atypical_PIKK_FRAP_MTOR_ST	Q5T4S7	UBR4	P42345	MTOR	S4117	T4116I	4116	Missense	proximal	-1	no	11.895	11.713	EPSD	TCGA	6.822	Down-regulation
Atypical_PIKK_FRAP_MTOR_ST	Q5T4S7	UBR4	P42345	MTOR	S4513	K4510I	4510	Missense	distal	-3	no	8.875	9.679	EPSD	TCGA;COSMIC	6.822	Up-regulation
Atypical_PIKK_FRAP_MTOR_ST	Q5T4S7	UBR4	P42345	MTOR	T4539	L4540P	4540	Missense	proximal	1	no	2.745	8.715	EPSD	TCGA;COSMIC	6.822	Gain
Atypical_PIKK_FRAP_MTOR_ST	Q5T4S7	UBR4	P42345	MTOR	S4973	R4967C	4967	Missense	distal	-6	no	7.913	8.039	EPSD	TCGA;COSMIC	6.822	Up-regulation
Atypical_PIKK_FRAP_MTOR_ST	Q5T4S7	UBR4	P42345	MTOR	S4973	R4967H	4967	Missense	distal	-6	no	7.913	7.106	EPSD	TCGA;COSMIC	6.822	Down-regulation
Atypical_PIKK_FRAP_MTOR_ST	Q5T4S7	UBR4	P42345	MTOR	S4973	A4969T	4969	Missense	distal	-4	no	7.913	8.374	EPSD	TCGA;COSMIC;CCLE	6.822	Up-regulation
Atypical_PIKK_FRAP_MTOR_ST	Q5T4S7	UBR4	P42345	MTOR	S5173	D5170Y	5170	Missense	distal	-3	no	12.773	12.888	EPSD	TCGA;COSMIC	6.822	Up-regulation
Atypical_PIKK_FRAP_MTOR_ST	Q5T4S7	UBR4	P42345	MTOR	S5173	F5174Y	5174	Missense	proximal	1	no	12.773	14.464	EPSD	TCGA;COSMIC	6.822	Up-regulation
Atypical_PIKK_FRAP_MTOR_ST	Q9H5H4	ZNF768	P42345	MTOR	S23	M21I	21	Missense	proximal	-2	no	11.283	11.367	EPSD	TCGA;ICGC;COSMIC	6.822	Up-regulation
Atypical_PIKK_FRAP_MTOR_ST	Q9H5H4	ZNF768	P42345	MTOR	S23	E25K	25	Missense	proximal	2	no	11.283	10.378	EPSD	TCGA;ICGC;COSMIC	6.822	Down-regulation
Atypical_PIKK_FRAP_MTOR_ST	Q9H5H4	ZNF768	P42345	MTOR	S23	E25Q	25	Missense	proximal	2	no	11.283	8.720	EPSD	TCGA;ICGC;COSMIC	6.822	Down-regulation
Atypical_PIKK_FRAP_MTOR_ST	Q9H5H4	ZNF768	P42345	MTOR	S69	E66Q	66	Missense	distal	-3	no	15.896	16.007	EPSD	TCGA;COSMIC	6.822	Up-regulation
Atypical_PIKK_FRAP_MTOR_ST	Q9H5H4	ZNF768	P42345	MTOR	S76	F79L	79	Missense	distal	3	no	7.904	5.231	EPSD	TCGA;ICGC;COSMIC	6.822	Loss
Atypical_PIKK_FRAP_MTOR_ST	Q9H5H4	ZNF768	P42345	MTOR	S83	F79L	79	Missense	distal	-4	no	11.657	11.317	EPSD	TCGA;ICGC;COSMIC	6.822	Down-regulation
Atypical_PIKK_FRAP_MTOR_ST	Q9H5H4	ZNF768	P42345	MTOR	S83	P84L	84	Missense	proximal	1	no	11.657	5.688	EPSD	TCGA;ICGC;COSMIC	6.822	Loss
Atypical_PIKK_FRAP_MTOR_ST	Q9H5H4	ZNF768	P42345	MTOR	S83	P84S	84	Missense	proximal	1	no	11.657	3.133	EPSD	TCGA;ICGC;COSMIC	6.822	Loss
Atypical_PIKK_FRAP_MTOR_ST	Q9H5H4	ZNF768	P42345	MTOR	S90	P91H	91	Missense	proximal	1	no	9.700	-17.491	EPSD	TCGA;ICGC;COSMIC	6.822	Loss
Atypical_PIKK_FRAP_MTOR_ST	Q9H5H4	ZNF768	P42345	MTOR	S90	P84L	84	Missense	distal	-6	no	9.700	8.925	EPSD	TCGA;ICGC;COSMIC	6.822	Down-regulation
Atypical_PIKK_FRAP_MTOR_ST	Q9H5H4	ZNF768	P42345	MTOR	S90	P84S	84	Missense	distal	-6	no	9.700	9.680	EPSD	TCGA;ICGC;COSMIC	6.822	Down-regulation
Atypical_PIKK_FRAP_MTOR_ST	Q9H5H4	ZNF768	P42345	MTOR	S97	P91H	91	Missense	distal	-6	no	11.915	11.195	EPSD	TCGA;ICGC;COSMIC	6.822	Down-regulation
Atypical_PIKK_FRAP_MTOR_ST	Q9H5H4	ZNF768	P42345	MTOR	S104	D108Y	108	Missense	distal	4	no	12.580	11.972	EPSD	TCGA;ICGC;COSMIC	6.822	Down-regulation
Atypical_PIKK_FRAP_MTOR_ST	Q9H5H4	ZNF768	P42345	MTOR	S111	E113K	113	Missense	proximal	2	no	10.214	9.309	EPSD	TCGA;ICGC;COSMIC	6.822	Down-regulation
Atypical_PIKK_FRAP_MTOR_ST	Q9H5H4	ZNF768	P42345	MTOR	S111	D108Y	108	Missense	distal	-3	no	10.214	10.328	EPSD	TCGA;ICGC;COSMIC	6.822	Up-regulation
Atypical_PIKK_FRAP_MTOR_ST	Q9H5H4	ZNF768	P42345	MTOR	S111	S116F	116	Missense	distal	5	no	10.214	10.801	EPSD	TCGA;COSMIC	6.822	Up-regulation
Atypical_PIKK_FRAP_MTOR_ST	Q9H5H4	ZNF768	P42345	MTOR	S132	R138W	138	Missense	distal	6	no	9.467	9.997	EPSD	TCGA;ICGC;COSMIC	6.822	Up-regulation
Atypical_PIKK_FRAP_MTOR_ST	Q9H5H4	ZNF768	P42345	MTOR	S139	E145Q	145	Missense	distal	6	no	10.411	8.804	PhosphoSitePlus	TCGA;COSMIC	6.822	Down-regulation
Atypical_PIKK_FRAP_MTOR_ST	Q9H5H4	ZNF768	P42345	MTOR	S139	R138W	138	Missense	proximal	-1	no	10.411	10.483	PhosphoSitePlus	TCGA;ICGC;COSMIC	6.822	Up-regulation
Atypical_PIKK_FRAP_MTOR_ST	Q9H5H4	ZNF768	P42345	MTOR	S139	E145D	145	Missense	distal	6	no	10.411	9.959	PhosphoSitePlus	TCGA;ICGC;COSMIC	6.822	Down-regulation
Atypical_PIKK_FRAP_MTOR_ST	Q9H5H4	ZNF768	P42345	MTOR	S167	A174V	174	Missense	distal	7	no	5.931	6.870	EPSD	TCGA;GDSC;CCLE	6.822	Gain
Atypical_PIKK_FRAP_MTOR_ST	Q9H5H4	ZNF768	P42345	MTOR	S274	G273S	273	Missense	proximal	-1	no	9.588	9.595	EPSD	TCGA;ICGC;COSMIC	6.822	Up-regulation
Atypical_PIKK_FRAP_MTOR_ST	Q9H5H4	ZNF768	P42345	MTOR	S274	R281H	281	Missense	distal	7	no	9.588	9.431	EPSD	TCGA;ICGC;COSMIC;GDSC;CCLE	6.822	Down-regulation
Atypical_PIKK_FRAP_MTOR_ST	Q9H5H4	ZNF768	P42345	MTOR	S330	Q336K	336	Missense	distal	6	no	11.094	11.797	EPSD	TCGA;COSMIC	6.822	Up-regulation
Atypical_PIKK_FRAP_MTOR_ST	Q9H5H4	ZNF768	P42345	MTOR	S330	R337H	337	Missense	distal	7	no	11.094	10.937	EPSD	TCGA;ICGC;COSMIC;GDSC;CCLE	6.822	Down-regulation
Atypical_PIKK_FRAP_MTOR_ST	Q9H5H4	ZNF768	P42345	MTOR	S330	R334C	334	Missense	distal	4	no	11.094	10.881	EPSD	TCGA;ICGC;COSMIC	6.822	Down-regulation
Atypical_PIKK_FRAP_MTOR_ST	Q9H5H4	ZNF768	P42345	MTOR	S330	A327T	327	Missense	distal	-3	no	11.094	11.148	EPSD	TCGA;ICGC;GDSC;CCLE	6.822	Up-regulation
Atypical_PIKK_FRAP_MTOR_ST	Q9H5H4	ZNF768	P42345	MTOR	S414	L416I	416	Missense	proximal	2	no	9.072	9.219	EPSD	TCGA	6.822	Up-regulation
Atypical_PIKK_FRAP_MTOR_ST	Q9H5H4	ZNF768	P42345	MTOR	S414	S414L	414	Missense	central	0	yes	9.072	0.000	EPSD	TCGA;ICGC;COSMIC	6.822	Loss
Atypical_PIKK_FRAP_MTOR_ST	Q9H5H4	ZNF768	P42345	MTOR	S414	P418S	418	Missense	distal	4	no	9.072	9.327	EPSD	TCGA;COSMIC	6.822	Up-regulation
Atypical_PIKK_FRAP_MTOR_ST	Q9H5H4	ZNF768	P42345	MTOR	S442	R437G	437	Missense	distal	-5	no	14.328	14.254	EPSD	TCGA;ICGC;COSMIC	6.822	Down-regulation
Atypical_PIKK_FRAP_MTOR_ST	Q9H5H4	ZNF768	P42345	MTOR	S442	A445G	445	Missense	distal	3	no	14.328	14.341	EPSD	TCGA;ICGC;COSMIC	6.822	Up-regulation
Atypical_PIKK_FRAP_MTOR_ST	Q9H063	MAF1	P42345	MTOR	S68	S73C	73	Missense	distal	5	no	10.497	11.274	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	6.822	Up-regulation
Atypical_PIKK_FRAP_MTOR_ST	Q9H063	MAF1	P42345	MTOR	S205	I198V	198	Missense	distal	-7	no	11.368	11.645	EPSD	TCGA;COSMIC	6.822	Up-regulation
Atypical_PIKK_FRAP_MTOR_ST	Q9Y2J4	AMOTL2	P42345	MTOR	S50	A53S	53	Missense	distal	3	no	12.738	11.683	EPSD	TCGA;COSMIC	6.822	Down-regulation
Atypical_PIKK_FRAP_MTOR_ST	Q9Y2J4	AMOTL2	P42345	MTOR	S50	G49R	49	Missense	proximal	-1	no	12.738	12.583	EPSD	TCGA;COSMIC	6.822	Down-regulation
Atypical_PIKK_FRAP_MTOR_ST	Q9Y2J4	AMOTL2	P42345	MTOR	S50	Q52H	52	Missense	proximal	2	no	12.738	12.372	EPSD	TCGA;COSMIC	6.822	Down-regulation
Atypical_PIKK_FRAP_MTOR_ST	Q9Y2J4	AMOTL2	P42345	MTOR	S236	H238Y	238	Missense	proximal	2	no	6.733	7.087	EPSD	TCGA;COSMIC	6.822	Gain
Atypical_PIKK_FRAP_MTOR_ST	Q9Y2J4	AMOTL2	P42345	MTOR	S236	R230W	230	Missense	distal	-6	no	6.733	7.106	EPSD	TCGA;ICGC;COSMIC	6.822	Gain
Atypical_PIKK_FRAP_MTOR_ST	Q9Y2J4	AMOTL2	P42345	MTOR	S540	R547Q	547	Missense	distal	7	no	11.791	11.392	EPSD	TCGA;COSMIC	6.822	Down-regulation
Atypical_PIKK_FRAP_MTOR_ST	Q9Y2J4	AMOTL2	P42345	MTOR	S602	S602Y	602	Missense	central	0	yes	10.857	0.000	EPSD	TCGA;COSMIC	6.822	Loss
Atypical_PIKK_FRAP_MTOR_ST	Q9Y2J4	AMOTL2	P42345	MTOR	S606	N612K	612	Missense	distal	6	no	8.561	9.059	EPSD	TCGA;ICGC;COSMIC	6.822	Up-regulation
Atypical_PIKK_FRAP_MTOR_ST	Q9Y2J4	AMOTL2	P42345	MTOR	S606	S602Y	602	Missense	distal	-4	no	8.561	7.930	EPSD	TCGA;COSMIC	6.822	Down-regulation
Atypical_PIKK_FRAP_MTOR_ST	Q9Y2J4	AMOTL2	P42345	MTOR	S609	N612K	612	Missense	distal	3	no	7.344	6.509	EPSD	TCGA;ICGC;COSMIC	6.822	Loss
Atypical_PIKK_FRAP_MTOR_ST	Q9Y2J4	AMOTL2	P42345	MTOR	S609	S602Y	602	Missense	distal	-7	no	7.344	7.255	EPSD	TCGA;COSMIC	6.822	Down-regulation
Atypical_PIKK_FRAP_MTOR_ST	P04198	MYCN	P42345	MTOR	S62	T58M	58	Missense	distal	-4	no	11.056	10.831	PhosphoSitePlus	TCGA;ICGC;COSMIC	6.822	Down-regulation
Atypical_PIKK_FRAP_MTOR_ST	P04198	MYCN	P42345	MTOR	S62	T58K	58	Missense	distal	-4	no	11.056	11.139	PhosphoSitePlus	TCGA;ICGC;COSMIC	6.822	Up-regulation
Atypical_PIKK_FRAP_MTOR_ST	P04198	MYCN	P42345	MTOR	S369	P372L	372	Missense	distal	3	no	8.029	5.774	EPSD	TCGA;ICGC	6.822	Loss
Atypical_PIKK_FRAP_MTOR_ST	P04198	MYCN	P42345	MTOR	S369	R373Q	373	Missense	distal	4	no	8.029	8.161	EPSD	TCGA;ICGC;COSMIC	6.822	Up-regulation
Atypical_PIKK_FRAP_MTOR_ST	P04198	MYCN	P42345	MTOR	S371	P372L	372	Missense	proximal	1	no	9.494	3.524	EPSD	TCGA;ICGC	6.822	Loss
Atypical_PIKK_FRAP_MTOR_ST	P04198	MYCN	P42345	MTOR	S371	S377T	377	Missense	distal	6	no	9.494	8.580	EPSD	TCGA;ICGC;COSMIC	6.822	Down-regulation
Atypical_PIKK_FRAP_MTOR_ST	P04198	MYCN	P42345	MTOR	S371	R373Q	373	Missense	proximal	2	no	9.494	9.482	EPSD	TCGA;ICGC;COSMIC	6.822	Down-regulation
Atypical_PIKK_FRAP_MTOR_ST	P04198	MYCN	P42345	MTOR	S377	P372L	372	Missense	distal	-5	no	7.775	7.703	EPSD	TCGA;ICGC	6.822	Down-regulation
Atypical_PIKK_FRAP_MTOR_ST	P04198	MYCN	P42345	MTOR	S377	R373Q	373	Missense	distal	-4	no	7.775	7.278	EPSD	TCGA;ICGC;COSMIC	6.822	Down-regulation
Atypical_PIKK_FRAP_MTOR_ST	P04198	MYCN	P42345	MTOR	S377	R382C	382	Missense	distal	5	no	7.775	7.559	EPSD	TCGA;ICGC;COSMIC	6.822	Down-regulation
Atypical_PIKK_FRAP_MTOR_ST	Q9H4A3	WNK1	P42345	MTOR	S19	A22S	22	Missense	distal	3	no	14.268	13.213	EPSD	TCGA;ICGC;COSMIC	6.822	Down-regulation
Atypical_PIKK_FRAP_MTOR_ST	Q9H4A3	WNK1	P42345	MTOR	S167	T160N	160	Missense	distal	-7	no	7.875	7.633	EPSD	TCGA;ICGC;COSMIC	6.822	Down-regulation
Atypical_PIKK_FRAP_MTOR_ST	Q9H4A3	WNK1	P42345	MTOR	S167	V172E	172	Missense	distal	5	no	7.875	6.369	EPSD	TCGA;ICGC;COSMIC	6.822	Loss
Atypical_PIKK_FRAP_MTOR_ST	Q9H4A3	WNK1	P42345	MTOR	T386	E388Q	388	Missense	proximal	2	no	11.873	9.310	EPSD	TCGA;ICGC;COSMIC	6.822	Down-regulation
Atypical_PIKK_FRAP_MTOR_ST	Q9H4A3	WNK1	P42345	MTOR	S1261	P1264S	1264	Missense	distal	3	no	12.184	12.198	EPSD	TCGA;COSMIC	6.822	Up-regulation
Atypical_PIKK_FRAP_MTOR_ST	Q9H4A3	WNK1	P42345	MTOR	S1261	E1265K	1265	Missense	distal	4	no	12.184	12.145	EPSD	TCGA;COSMIC	6.822	Down-regulation
Atypical_PIKK_FRAP_MTOR_ST	Q9H4A3	WNK1	P42345	MTOR	S1261	R1267L	1267	Missense	distal	6	no	12.184	12.817	EPSD	TCGA;COSMIC;GDSC;CCLE	6.822	Up-regulation
Atypical_PIKK_FRAP_MTOR_ST	Q9H4A3	WNK1	P42345	MTOR	S1261	A1254V	1254	Missense	distal	-7	no	12.184	12.296	EPSD	TCGA;COSMIC;CCLE	6.822	Up-regulation
Atypical_PIKK_FRAP_MTOR_ST	Q9H4A3	WNK1	P42345	MTOR	S1289	H1296D	1296	Missense	distal	7	no	15.941	15.867	EPSD	TCGA;COSMIC	6.822	Down-regulation
Atypical_PIKK_FRAP_MTOR_ST	Q9H4A3	WNK1	P42345	MTOR	S1289	S1289N	1289	Missense	central	0	yes	15.941	0.000	EPSD	TCGA	6.822	Loss
Atypical_PIKK_FRAP_MTOR_ST	Q9H4A3	WNK1	P42345	MTOR	S1299	S1300P	1300	Missense	proximal	1	no	5.808	14.332	EPSD	TCGA;COSMIC	6.822	Gain
Atypical_PIKK_FRAP_MTOR_ST	Q9H4A3	WNK1	P42345	MTOR	S1838	Q1839P	1839	Missense	proximal	1	no	2.764	11.378	EPSD	TCGA;COSMIC	6.822	Gain
Atypical_PIKK_FRAP_MTOR_ST	Q9H4A3	WNK1	P42345	MTOR	S1899	E1901D	1901	Missense	proximal	2	no	10.216	9.235	EPSD	TCGA;COSMIC	6.822	Down-regulation
Atypical_PIKK_FRAP_MTOR_ST	Q9H4A3	WNK1	P42345	MTOR	S1902	P1909L	1909	Missense	distal	7	no	6.512	7.468	EPSD	TCGA;COSMIC	6.822	Gain
Atypical_PIKK_FRAP_MTOR_ST	Q9H4A3	WNK1	P42345	MTOR	S1978	A1977V	1977	Missense	proximal	-1	no	8.996	8.924	EPSD	TCGA;COSMIC	6.822	Down-regulation
Atypical_PIKK_FRAP_MTOR_ST	Q9H4A3	WNK1	P42345	MTOR	S1978	P1980R	1980	Missense	proximal	2	no	8.996	6.789	EPSD	TCGA;COSMIC	6.822	Loss
Atypical_PIKK_FRAP_MTOR_ST	Q9H4A3	WNK1	P42345	MTOR	S1978	K1972N	1972	Missense	distal	-6	no	8.996	8.540	EPSD	TCGA;COSMIC	6.822	Down-regulation
Atypical_PIKK_FRAP_MTOR_ST	Q9H4A3	WNK1	P42345	MTOR	S2011	A2016V	2016	Missense	distal	5	no	6.334	7.028	EPSD	TCGA;COSMIC	6.822	Gain
Atypical_PIKK_FRAP_MTOR_ST	Q9H4A3	WNK1	P42345	MTOR	S2029	Q2035H	2035	Missense	distal	6	no	8.544	8.476	EPSD	TCGA;COSMIC	6.822	Down-regulation
Atypical_PIKK_FRAP_MTOR_ST	Q9H4A3	WNK1	P42345	MTOR	S2029	G2028S	2028	Missense	proximal	-1	no	8.544	8.551	EPSD	TCGA;GDSC;CCLE	6.822	Up-regulation
Atypical_PIKK_FRAP_MTOR_ST	Q9H4A3	WNK1	P42345	MTOR	S2032	Q2035H	2035	Missense	distal	3	no	8.691	10.127	PhosphoSitePlus	TCGA;COSMIC	6.822	Up-regulation
Atypical_PIKK_FRAP_MTOR_ST	Q9H4A3	WNK1	P42345	MTOR	S2032	G2028S	2028	Missense	distal	-4	no	8.691	9.258	PhosphoSitePlus	TCGA;GDSC;CCLE	6.822	Up-regulation
Atypical_PIKK_FRAP_MTOR_ST	Q9H4A3	WNK1	P42345	MTOR	S2140	S2145N	2145	Missense	distal	5	no	6.226	7.708	EPSD	TCGA;COSMIC	6.822	Gain
Atypical_PIKK_FRAP_MTOR_ST	Q9H4A3	WNK1	P42345	MTOR	S2145	L2148F	2148	Missense	distal	3	no	6.271	8.945	EPSD	TCGA;COSMIC	6.822	Gain
Atypical_PIKK_FRAP_MTOR_ST	Q9H4A3	WNK1	P42345	MTOR	S2188	D2192E	2192	Missense	distal	4	no	12.014	11.853	EPSD	TCGA;COSMIC	6.822	Down-regulation
Atypical_PIKK_FRAP_MTOR_ST	Q9H4A3	WNK1	P42345	MTOR	T2245	H2251P	2251	Missense	distal	6	no	5.839	7.315	EPSD	TCGA;COSMIC	6.822	Gain
Atypical_PIKK_FRAP_MTOR_ST	Q9H4A3	WNK1	P42345	MTOR	S2370	S2370F	2370	Missense	central	0	yes	12.717	0.000	EPSD	TCGA;COSMIC	6.822	Loss
Atypical_PIKK_FRAP_MTOR_ST	Q9H4A3	WNK1	P42345	MTOR	S2372	S2370F	2370	Missense	proximal	-2	no	6.675	6.854	EPSD	TCGA;COSMIC	6.822	Gain
Other_NEK_NEK6_NEK6_ST	O95235	KIF20A	Q9HC98	NEK6	S104	S104Y	104	Missense	central	0	yes	90.928	0.000	EPSD	TCGA;ICGC	73.015	Loss
Other_NEK_NEK6_NEK6_ST	O95235	KIF20A	Q9HC98	NEK6	S240	K242N	242	Missense	proximal	2	no	115.933	118.092	EPSD;PhosphoSitePlus	TCGA;COSMIC	73.015	Up-regulation
Other_NEK_NEK6_NEK6_ST	O95235	KIF20A	Q9HC98	NEK6	S244	K242N	242	Missense	proximal	-2	no	113.449	111.285	EPSD;PhosphoSitePlus	TCGA;COSMIC	73.015	Down-regulation
Other_NEK_NEK6_NEK6_ST	O95235	KIF20A	Q9HC98	NEK6	S244	R250Q	250	Missense	distal	6	no	113.449	113.466	EPSD;PhosphoSitePlus	TCGA	73.015	Up-regulation
Other_NEK_NEK6_NEK6_ST	O95235	KIF20A	Q9HC98	NEK6	T279	R282Q	282	Missense	distal	3	no	86.783	86.834	EPSD	TCGA;ICGC;COSMIC	73.015	Up-regulation
Other_NEK_NEK6_NEK6_ST	O95235	KIF20A	Q9HC98	NEK6	S677	R675Q	675	Missense	proximal	-2	no	76.103	82.466	EPSD	TCGA;ICGC;COSMIC	73.015	Up-regulation
Other_NEK_NEK6_NEK6_ST	O95235	KIF20A	Q9HC98	NEK6	S677	R676W	676	Missense	proximal	-1	no	76.103	67.062	EPSD	TCGA;ICGC;COSMIC	73.015	Loss
Other_NEK_NEK6_NEK6_ST	O95235	KIF20A	Q9HC98	NEK6	S683	R676W	676	Missense	distal	-7	no	107.958	107.404	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	73.015	Down-regulation
Other_NEK_NEK6_NEK6_ST	O95235	KIF20A	Q9HC98	NEK6	S754	E747K	747	Missense	distal	-7	no	116.554	116.822	PhosphoSitePlus;EPSD	TCGA;COSMIC	73.015	Up-regulation
Other_NEK_NEK6_NEK6_ST	O95235	KIF20A	Q9HC98	NEK6	S754	E759Q	759	Missense	distal	5	no	116.554	116.019	PhosphoSitePlus;EPSD	TCGA;ICGC;COSMIC	73.015	Down-regulation
Other_NEK_NEK6_NEK6_ST	O95235	KIF20A	Q9HC98	NEK6	S883	K889N	889	Missense	distal	6	no	110.050	109.219	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	73.015	Down-regulation
Other_NEK_NEK6_NEK6_ST	O95235	KIF20A	Q9HC98	NEK6	S883	R877H	877	Missense	distal	-6	no	110.050	109.846	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	73.015	Down-regulation
Other_NEK_NEK6_NEK6_ST	O95235	KIF20A	Q9HC98	NEK6	S883	S883F	883	Missense	central	0	yes	110.050	0.000	EPSD;PhosphoSitePlus	TCGA	73.015	Loss
Other_NEK_NEK6_NEK6_ST	P23443	RPS6KB1	Q9HC98	NEK6	S53	G48S	48	Missense	distal	-5	no	115.946	115.992	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	73.015	Up-regulation
Other_NEK_NEK6_NEK6_ST	P23443	RPS6KB1	Q9HC98	NEK6	S53	G57E	57	Missense	distal	4	no	115.946	117.996	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	73.015	Up-regulation
Other_NEK_NEK6_NEK6_ST	P23443	RPS6KB1	Q9HC98	NEK6	S75	E73K	73	Missense	proximal	-2	no	71.082	77.392	EPSD	TCGA;ICGC;COSMIC	73.015	Gain
Other_NEK_NEK6_NEK6_ST	P23443	RPS6KB1	Q9HC98	NEK6	S394	Q389E	389	Missense	distal	-5	no	108.869	108.788	EPSD	TCGA;COSMIC	73.015	Down-regulation
Other_NEK_NEK6_NEK6_ST	Q08345	DDR1	Q9HC98	NEK6	T469	D468N	468	Missense	proximal	-1	no	82.075	80.950	EPSD	TCGA;ICGC	73.015	Down-regulation
Other_NEK_NEK6_NEK6_ST	Q08345	DDR1	Q9HC98	NEK6	T469	P466S	466	Missense	distal	-3	no	82.075	-13.676	EPSD	TCGA;ICGC;COSMIC	73.015	Loss
Other_NEK_NEK6_NEK6_ST	Q08345	DDR1	Q9HC98	NEK6	T469	R475C	475	Missense	distal	6	no	82.075	81.466	EPSD	TCGA;COSMIC	73.015	Down-regulation
Other_NEK_NEK6_NEK6_ST	Q96AP0	ACD	Q9HC98	NEK6	S255	A250T	250	Missense	distal	-5	no	109.389	109.464	EPSD	TCGA;COSMIC	73.015	Up-regulation
Other_NEK_NEK6_NEK6_ST	Q96AP0	ACD	Q9HC98	NEK6	S255	S255F	255	Missense	central	0	yes	109.389	0.000	EPSD	TCGA	73.015	Loss
Other_NEK_NEK6_NEK6_ST	Q96AP0	ACD	Q9HC98	NEK6	S255	R262W	262	Missense	distal	7	no	109.389	110.070	EPSD	TCGA;COSMIC	73.015	Up-regulation
Other_NEK_NEK6_NEK6_ST	Q96AP0	ACD	Q9HC98	NEK6	S420	R421C	421	Missense	proximal	1	no	72.476	73.255	EPSD	TCGA;COSMIC	73.015	Gain
Other_NEK_NEK6_NEK6_ST	Q96AP0	ACD	Q9HC98	NEK6	S435	P432L	432	Missense	distal	-3	no	80.738	87.170	EPSD	TCGA;COSMIC	73.015	Up-regulation
Other_NEK_NEK6_NEK6_ST	Q96AP0	ACD	Q9HC98	NEK6	S510	P507L	507	Missense	distal	-3	no	76.360	82.793	EPSD	TCGA;COSMIC	73.015	Up-regulation
Other_NEK_NEK6_NEK6_ST	Q08999	RBL2	Q9HC98	NEK6	T421	S420F	420	Missense	proximal	-1	no	84.338	83.204	EPSD	TCGA;COSMIC	73.015	Down-regulation
Other_NEK_NEK6_NEK6_ST	Q08999	RBL2	Q9HC98	NEK6	T421	R428C	428	Missense	distal	7	no	84.338	83.967	EPSD	TCGA;COSMIC	73.015	Down-regulation
Other_NEK_NEK6_NEK6_ST	Q08999	RBL2	Q9HC98	NEK6	S659	P663A	663	Missense	distal	4	no	114.357	116.485	PhosphoSitePlus	TCGA;ICGC;COSMIC	73.015	Up-regulation
Other_NEK_NEK6_NEK6_ST	Q08999	RBL2	Q9HC98	NEK6	S659	T653N	653	Missense	distal	-6	no	114.357	114.262	PhosphoSitePlus	TCGA;ICGC	73.015	Down-regulation
Other_NEK_NEK6_NEK6_ST	Q08999	RBL2	Q9HC98	NEK6	S1035	P1032L	1032	Missense	distal	-3	no	73.595	80.028	EPSD	TCGA;ICGC;COSMIC	73.015	Up-regulation
Other_NEK_NEK6_NEK6_ST	Q08999	RBL2	Q9HC98	NEK6	S1035	P1033T	1033	Missense	proximal	-2	no	73.595	74.430	EPSD	TCGA;ICGC;COSMIC	73.015	Up-regulation
Other_NEK_NEK6_NEK6_ST	Q08999	RBL2	Q9HC98	NEK6	S1080	K1083Q	1083	Missense	distal	3	no	78.289	78.409	EPSD	TCGA	73.015	Up-regulation
Other_NEK_NEK6_NEK6_ST	P52948	NUP98	Q9HC98	NEK6	S243	G249D	249	Missense	distal	6	no	88.975	90.042	EPSD	TCGA;ICGC	73.015	Up-regulation
Other_NEK_NEK6_NEK6_ST	P52948	NUP98	Q9HC98	NEK6	S244	G249D	249	Missense	distal	5	no	77.772	82.986	EPSD	TCGA;ICGC	73.015	Up-regulation
Other_NEK_NEK6_NEK6_ST	P52948	NUP98	Q9HC98	NEK6	S262	S262G	262	Missense	central	0	yes	78.297	0.000	EPSD	TCGA;ICGC;COSMIC	73.015	Loss
Other_NEK_NEK6_NEK6_ST	P52948	NUP98	Q9HC98	NEK6	S704	S709C	709	Missense	distal	5	no	79.988	78.276	EPSD	TCGA;ICGC;COSMIC	73.015	Down-regulation
Other_NEK_NEK6_NEK6_ST	P52948	NUP98	Q9HC98	NEK6	S839	S839L	839	Missense	central	0	yes	111.564	0.000	EPSD	TCGA;ICGC;COSMIC	73.015	Loss
Other_NEK_NEK6_NEK6_ST	P52948	NUP98	Q9HC98	NEK6	S1064	P1071S	1071	Missense	distal	7	no	89.758	90.338	EPSD	TCGA;ICGC;COSMIC	73.015	Up-regulation
Other_NEK_NEK6_NEK6_ST	P52948	NUP98	Q9HC98	NEK6	S1083	V1087A	1087	Missense	distal	4	no	86.769	89.471	EPSD	TCGA;ICGC;COSMIC	73.015	Up-regulation
Other_NEK_NEK6_NEK6_ST	P52948	NUP98	Q9HC98	NEK6	S1083	P1088R	1088	Missense	distal	5	no	86.769	88.052	EPSD	TCGA;ICGC;COSMIC	73.015	Up-regulation
Other_NEK_NEK6_NEK6_ST	P52732	KIF11	Q9HC98	NEK6	S36	R33L	33	Missense	distal	-3	no	21.614	99.077	EPSD	TCGA;ICGC;COSMIC	73.015	Gain
Other_NEK_NEK6_NEK6_ST	P52732	KIF11	Q9HC98	NEK6	S75	G73E	73	Missense	proximal	-2	no	76.268	67.916	EPSD	TCGA;ICGC;COSMIC	73.015	Loss
Other_NEK_NEK6_NEK6_ST	P52732	KIF11	Q9HC98	NEK6	S323	D322E	322	Missense	proximal	-1	no	81.545	81.087	EPSD	TCGA	73.015	Down-regulation
Other_NEK_NEK6_NEK6_ST	P50613	CDK7	Q9HC98	NEK6	T110	N105T	105	Missense	distal	-5	no	82.249	82.512	EPSD	TCGA;COSMIC	73.015	Up-regulation
Other_NEK_NEK6_NEK6_ST	P50613	CDK7	Q9HC98	NEK6	T110	K115N	115	Missense	distal	5	no	82.249	80.290	EPSD	TCGA	73.015	Down-regulation
Other_NEK_NEK6_NEK6_ST	P50613	CDK7	Q9HC98	NEK6	S112	N105T	105	Missense	distal	-7	no	87.819	87.954	EPSD	TCGA;COSMIC	73.015	Up-regulation
Other_NEK_NEK6_NEK6_ST	P50613	CDK7	Q9HC98	NEK6	S112	K115N	115	Missense	distal	3	no	87.819	87.927	EPSD	TCGA	73.015	Up-regulation
Other_NEK_NEK6_NEK6_ST	P50613	CDK7	Q9HC98	NEK6	S161	A159T	159	Missense	proximal	-2	no	119.091	116.515	PhosphoSitePlus	TCGA;COSMIC	73.015	Down-regulation
Other_NEK_NEK6_NEK6_ST	P50613	CDK7	Q9HC98	NEK6	S161	P165R	165	Missense	distal	4	no	119.091	116.857	PhosphoSitePlus	TCGA;COSMIC	73.015	Down-regulation
Other_NEK_NEK6_NEK6_ST	P50613	CDK7	Q9HC98	NEK6	S161	N166D	166	Missense	distal	5	no	119.091	122.292	PhosphoSitePlus	TCGA;COSMIC	73.015	Up-regulation
Other_NEK_NEK6_NEK6_ST	P50613	CDK7	Q9HC98	NEK6	S217	D220H	220	Missense	distal	3	no	80.732	80.901	EPSD	TCGA;COSMIC	73.015	Up-regulation
Other_NEK_NEK6_NEK6_ST	P50613	CDK7	Q9HC98	NEK6	T316	R309K	309	Missense	distal	-7	no	79.516	79.694	EPSD	TCGA;COSMIC	73.015	Up-regulation
Other_NEK_NEK6_NEK6_ST	P40763	STAT3	Q9HC98	NEK6	T433	E435K	435	Missense	proximal	2	no	79.952	79.848	EPSD	TCGA;ICGC;COSMIC	73.015	Down-regulation
Other_NEK_NEK6_NEK6_ST	P40763	STAT3	Q9HC98	NEK6	T433	D427G	427	Missense	distal	-6	no	79.952	79.419	EPSD	TCGA;ICGC;COSMIC	73.015	Down-regulation
Other_NEK_NEK6_NEK6_ST	P40763	STAT3	Q9HC98	NEK6	T433	T440I	440	Missense	distal	7	no	79.952	81.258	EPSD	TCGA	73.015	Up-regulation
Other_NEK_NEK6_NEK6_ST	P40763	STAT3	Q9HC98	NEK6	S727	R729H	729	Missense	proximal	2	no	112.082	113.007	PhosphoSitePlus	TCGA;ICGC;COSMIC;GDSC;CCLE	73.015	Up-regulation
Other_NEK_NEK6_NEK6_ST	P40763	STAT3	Q9HC98	NEK6	S727	P725L	725	Missense	proximal	-2	no	112.082	109.781	PhosphoSitePlus	TCGA;ICGC;COSMIC	73.015	Down-regulation
Other_NEK_NEK6_NEK6_ST	Q05586	GRIN1	Q9HC98	NEK6	S14	T8M	8	Missense	distal	-6	no	74.181	73.874	EPSD	TCGA;ICGC;COSMIC	73.015	Down-regulation
Other_NEK_NEK6_NEK6_ST	Q05586	GRIN1	Q9HC98	NEK6	T122	R124G	124	Missense	proximal	2	no	83.571	83.978	EPSD	TCGA;ICGC;COSMIC	73.015	Up-regulation
Other_NEK_NEK6_NEK6_ST	P0DMV8	HSPA1A	Q9HC98	NEK6	T14	D10N	10	Missense	distal	-4	no	82.835	82.367	EPSD	TCGA;ICGC;COSMIC	73.015	Down-regulation
Other_NEK_NEK6_NEK6_ST	P0DMV8	HSPA1A	Q9HC98	NEK6	T14	L11P	11	Missense	distal	-3	no	82.835	76.403	EPSD	TCGA	73.015	Down-regulation
Other_NEK_NEK6_NEK6_ST	P0DMV8	HSPA1A	Q9HC98	NEK6	T66	R72W	72	Missense	distal	6	no	104.275	102.766	PhosphoSitePlus	TCGA;ICGC;COSMIC	73.015	Down-regulation
Other_NEK_NEK6_NEK6_ST	P0DMV8	HSPA1A	Q9HC98	NEK6	T66	D69V	69	Missense	distal	3	no	104.275	104.395	PhosphoSitePlus	TCGA;ICGC;COSMIC	73.015	Up-regulation
Other_NEK_NEK6_NEK6_ST	P0DMV8	HSPA1A	Q9HC98	NEK6	S608	I607M	607	Missense	proximal	-1	no	74.623	80.058	EPSD	TCGA;ICGC;COSMIC	73.015	Up-regulation
Other_NEK_NEK6_NEK6_ST	P0DMV8	HSPA1A	Q9HC98	NEK6	S608	L610R	610	Missense	proximal	2	no	74.623	76.836	EPSD	TCGA;COSMIC	73.015	Up-regulation
Other_NEK_NEK6_NEK6_ST	P0DMV8	HSPA1A	Q9HC98	NEK6	S608	S608N	608	Missense	central	0	yes	74.623	0.000	EPSD	TCGA;ICGC;COSMIC	73.015	Loss
Other_NEK_NEK6_NEK6_ST	P0DMV8	HSPA1A	Q9HC98	NEK6	S608	A614V	614	Missense	distal	6	no	74.623	74.507	EPSD	TCGA	73.015	Down-regulation
CK1_CK1_CK1-A_CSNK1A1_ST	P02730	SLC4A1	P48729	CSNK1A1	S29	E32D	32	Missense	distal	3	no	20.959	21.098	EPSD	TCGA;ICGC;COSMIC	20.411	Up-regulation
CK1_CK1_CK1-A_CSNK1A1_ST	P02730	SLC4A1	P48729	CSNK1A1	S29	P34L	34	Missense	distal	5	no	20.959	21.023	EPSD	TCGA	20.411	Up-regulation
CK1_CK1_CK1-A_CSNK1A1_ST	P02730	SLC4A1	P48729	CSNK1A1	S29	P24T	24	Missense	distal	-5	no	20.959	20.759	EPSD	TCGA;ICGC	20.411	Down-regulation
CK1_CK1_CK1-A_CSNK1A1_ST	P02730	SLC4A1	P48729	CSNK1A1	S29	Q30H	30	Missense	proximal	1	no	20.959	20.532	EPSD	TCGA;ICGC	20.411	Down-regulation
CK1_CK1_CK1-A_CSNK1A1_ST	P02730	SLC4A1	P48729	CSNK1A1	S29	P24S	24	Missense	distal	-5	no	20.959	21.391	EPSD	TCGA;ICGC;COSMIC	20.411	Up-regulation
CK1_CK1_CK1-A_CSNK1A1_ST	P02730	SLC4A1	P48729	CSNK1A1	S303	R304P	304	Missense	proximal	1	no	20.723	20.929	PhosphoSitePlus;EPSD	TCGA;ICGC;COSMIC	20.411	Up-regulation
CK1_CK1_CK1-A_CSNK1A1_ST	P02730	SLC4A1	P48729	CSNK1A1	S303	L308M	308	Missense	distal	5	no	20.723	20.527	PhosphoSitePlus;EPSD	TCGA;ICGC;COSMIC	20.411	Down-regulation
CK1_CK1_CK1-A_CSNK1A1_ST	P02730	SLC4A1	P48729	CSNK1A1	S303	E306K	306	Missense	distal	3	no	20.723	16.593	PhosphoSitePlus;EPSD	TCGA;ICGC;COSMIC	20.411	Loss
CK1_CK1_CK1-A_CSNK1A1_ST	P02730	SLC4A1	P48729	CSNK1A1	S402	A400S	400	Missense	proximal	-2	no	22.377	23.336	EPSD	TCGA;ICGC;COSMIC	20.411	Up-regulation
CK1_CK1_CK1-A_CSNK1A1_ST	P02730	SLC4A1	P48729	CSNK1A1	S402	D399N	399	Missense	distal	-3	no	22.377	17.097	EPSD	TCGA;ICGC;COSMIC	20.411	Loss
CK1_CK1_CK1-A_CSNK1A1_ST	P55316	FOXG1	P48729	CSNK1A1	S228	R230H	230	Missense	proximal	2	no	23.055	22.329	EPSD	TCGA;ICGC;COSMIC	20.411	Down-regulation
CK1_CK1_CK1-A_CSNK1A1_ST	P55316	FOXG1	P48729	CSNK1A1	S228	S234A	234	Missense	distal	6	no	23.055	22.697	EPSD	TCGA;ICGC;COSMIC	20.411	Down-regulation
CK1_CK1_CK1-A_CSNK1A1_ST	P55316	FOXG1	P48729	CSNK1A1	S228	Q223H	223	Missense	distal	-5	no	23.055	21.760	EPSD	TCGA;ICGC;COSMIC	20.411	Down-regulation
CK1_CK1_CK1-A_CSNK1A1_ST	P55316	FOXG1	P48729	CSNK1A1	S228	R230G	230	Missense	proximal	2	no	23.055	24.007	EPSD	TCGA;ICGC;COSMIC	20.411	Up-regulation
CK1_CK1_CK1-A_CSNK1A1_ST	P55316	FOXG1	P48729	CSNK1A1	S228	S234P	234	Missense	distal	6	no	23.055	22.829	EPSD	TCGA;ICGC;COSMIC	20.411	Down-regulation
CK1_CK1_CK1-A_CSNK1A1_ST	P17302	GJA1	P48729	CSNK1A1	S325	S330F	330	Missense	distal	5	no	22.566	23.073	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	20.411	Up-regulation
CK1_CK1_CK1-A_CSNK1A1_ST	P17302	GJA1	P48729	CSNK1A1	S325	A332T	332	Missense	distal	7	no	22.566	22.546	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	20.411	Down-regulation
CK1_CK1_CK1-A_CSNK1A1_ST	P17302	GJA1	P48729	CSNK1A1	S325	G324E	324	Missense	proximal	-1	no	22.566	22.924	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	20.411	Up-regulation
CK1_CK1_CK1-A_CSNK1A1_ST	P17302	GJA1	P48729	CSNK1A1	S325	R319Q	319	Missense	distal	-6	no	22.566	22.755	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	20.411	Up-regulation
CK1_CK1_CK1-A_CSNK1A1_ST	P17302	GJA1	P48729	CSNK1A1	S328	S330F	330	Missense	proximal	2	no	24.471	23.449	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	20.411	Down-regulation
CK1_CK1_CK1-A_CSNK1A1_ST	P17302	GJA1	P48729	CSNK1A1	S328	A332T	332	Missense	distal	4	no	24.471	24.460	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	20.411	Down-regulation
CK1_CK1_CK1-A_CSNK1A1_ST	P17302	GJA1	P48729	CSNK1A1	S328	G324E	324	Missense	distal	-4	no	24.471	24.864	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	20.411	Up-regulation
CK1_CK1_CK1-A_CSNK1A1_ST	P27348	YWHAQ	P48729	CSNK1A1	S37	E35K	35	Missense	proximal	-2	no	21.769	20.456	EPSD	TCGA	20.411	Down-regulation
CK1_CK1_CK1-A_CSNK1A1_ST	Q13148	TARDBP	P48729	CSNK1A1	S91	S91L	91	Missense	central	0	yes	21.307	0.000	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	20.411	Loss
CK1_CK1_CK1-A_CSNK1A1_ST	Q13148	TARDBP	P48729	CSNK1A1	S183	E186Q	186	Missense	distal	3	no	23.255	20.684	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	20.411	Down-regulation
CK1_CK1_CK1-A_CSNK1A1_ST	Q13148	TARDBP	P48729	CSNK1A1	S242	D247N	247	Missense	distal	5	no	26.009	26.255	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	20.411	Up-regulation
CK1_CK1_CK1-A_CSNK1A1_ST	Q13148	TARDBP	P48729	CSNK1A1	S305	G304S	304	Missense	proximal	-1	no	21.779	21.080	EPSD;PhosphoSitePlus	TCGA;COSMIC	20.411	Down-regulation
CK1_CK1_CK1-A_CSNK1A1_ST	Q13148	TARDBP	P48729	CSNK1A1	S387	S393P	393	Missense	distal	6	no	21.016	20.790	EPSD;PhosphoSitePlus	TCGA;COSMIC	20.411	Down-regulation
CK1_CK1_CK1-A_CSNK1A1_ST	Q13148	TARDBP	P48729	CSNK1A1	S387	S393L	393	Missense	distal	6	no	21.016	20.876	EPSD;PhosphoSitePlus	TCGA;COSMIC	20.411	Down-regulation
CK1_CK1_CK1-A_CSNK1A1_ST	Q13148	TARDBP	P48729	CSNK1A1	S389	S393P	393	Missense	distal	4	no	24.096	24.059	EPSD;PhosphoSitePlus	TCGA;COSMIC	20.411	Down-regulation
CK1_CK1_CK1-A_CSNK1A1_ST	Q13148	TARDBP	P48729	CSNK1A1	S389	S393L	393	Missense	distal	4	no	24.096	24.126	EPSD;PhosphoSitePlus	TCGA;COSMIC	20.411	Up-regulation
CK1_CK1_CK1-A_CSNK1A1_ST	Q13148	TARDBP	P48729	CSNK1A1	S403	S407C	407	Missense	distal	4	no	21.283	21.164	EPSD;PhosphoSitePlus	TCGA;COSMIC	20.411	Down-regulation
CK1_CK1_CK1-A_CSNK1A1_ST	Q13148	TARDBP	P48729	CSNK1A1	S407	S407C	407	Missense	central	0	yes	22.948	0.000	EPSD;PhosphoSitePlus	TCGA;COSMIC	20.411	Loss
CK1_CK1_CK1-A_CSNK1A1_ST	Q13148	TARDBP	P48729	CSNK1A1	S410	S407C	407	Missense	distal	-3	no	21.529	17.196	EPSD;PhosphoSitePlus	TCGA;COSMIC	20.411	Loss
CK1_CK1_CK1-A_CSNK1A1_ST	P98177	FOXO4	P48729	CSNK1A1	S8	P3A	3	Missense	distal	-5	no	21.082	20.202	EPSD	TCGA;ICGC;COSMIC	20.411	Loss
CK1_CK1_CK1-A_CSNK1A1_ST	P98177	FOXO4	P48729	CSNK1A1	S8	E6D	6	Missense	proximal	-2	no	21.082	20.966	EPSD	TCGA;ICGC;COSMIC	20.411	Down-regulation
CK1_CK1_CK1-A_CSNK1A1_ST	P98177	FOXO4	P48729	CSNK1A1	S8	A14T	14	Missense	distal	6	no	21.082	21.336	EPSD	TCGA;ICGC;COSMIC	20.411	Up-regulation
CK1_CK1_CK1-A_CSNK1A1_ST	P98177	FOXO4	P48729	CSNK1A1	S8	P3Q	3	Missense	distal	-5	no	21.082	21.441	EPSD	TCGA;ICGC	20.411	Up-regulation
CK1_CK1_CK1-A_CSNK1A1_ST	P98177	FOXO4	P48729	CSNK1A1	S111	A113V	113	Missense	proximal	2	no	20.785	20.342	EPSD	TCGA;COSMIC	20.411	Loss
CK1_CK1_CK1-A_CSNK1A1_ST	P98177	FOXO4	P48729	CSNK1A1	S111	Q112H	112	Missense	proximal	1	no	20.785	20.359	EPSD	TCGA;COSMIC	20.411	Loss
CK1_CK1_CK1-A_CSNK1A1_ST	P98177	FOXO4	P48729	CSNK1A1	S146	S144I	144	Missense	proximal	-2	no	28.504	26.325	EPSD	TCGA	20.411	Down-regulation
CK1_CK1_CK1-A_CSNK1A1_ST	P98177	FOXO4	P48729	CSNK1A1	S197	R192H	192	Missense	distal	-5	no	20.505	20.007	EPSD	TCGA;ICGC;COSMIC	20.411	Loss
CK1_CK1_CK1-A_CSNK1A1_ST	P98177	FOXO4	P48729	CSNK1A1	S197	S202R	202	Missense	distal	5	no	20.505	20.914	EPSD	TCGA;COSMIC	20.411	Up-regulation
CK1_CK1_CK1-A_CSNK1A1_ST	P98177	FOXO4	P48729	CSNK1A1	S197	R192C	192	Missense	distal	-5	no	20.505	20.072	EPSD	TCGA;ICGC;COSMIC	20.411	Loss
CK1_CK1_CK1-A_CSNK1A1_ST	P98177	FOXO4	P48729	CSNK1A1	S202	L205I	205	Missense	distal	3	no	18.445	20.941	EPSD	TCGA	20.411	Gain
CK1_CK1_CK1-A_CSNK1A1_ST	P98177	FOXO4	P48729	CSNK1A1	S317	S322R	322	Missense	distal	5	no	22.231	22.640	EPSD	TCGA;COSMIC	20.411	Up-regulation
CK1_CK1_CK1-A_CSNK1A1_ST	P98177	FOXO4	P48729	CSNK1A1	S317	R321W	321	Missense	distal	4	no	22.231	21.955	EPSD	TCGA;COSMIC	20.411	Down-regulation
CK1_CK1_CK1-A_CSNK1A1_ST	P98177	FOXO4	P48729	CSNK1A1	S317	L312V	312	Missense	distal	-5	no	22.231	21.100	EPSD	TCGA;COSMIC	20.411	Down-regulation
CK1_CK1_CK1-A_CSNK1A1_ST	O15151	MDM4	P48729	CSNK1A1	S289	S287C	287	Missense	proximal	-2	no	27.589	26.271	PhosphoSitePlus	TCGA;ICGC;COSMIC	20.411	Down-regulation
CK1_CK1_CK1-A_CSNK1A1_ST	Q9Y2W7	KCNIP3	P48729	CSNK1A1	S63	S70F	70	Missense	distal	7	no	21.449	21.637	PhosphoSitePlus	TCGA;ICGC;COSMIC	20.411	Up-regulation
CK1_CK1_CK1-A_CSNK1A1_ST	Q9Y2W7	KCNIP3	P48729	CSNK1A1	S63	E66K	66	Missense	distal	3	no	21.449	17.319	PhosphoSitePlus	TCGA;ICGC;COSMIC	20.411	Loss
CK1_CK1_CK1-A_CSNK1A1_ST	Q9Y2W7	KCNIP3	P48729	CSNK1A1	S63	D64N	64	Missense	proximal	1	no	21.449	21.219	PhosphoSitePlus	TCGA;ICGC;COSMIC	20.411	Down-regulation
CK1_CK1_CK1-A_CSNK1A1_ST	Q9BXL7	CARD11	P48729	CSNK1A1	S538	P536S	536	Missense	proximal	-2	no	19.459	21.330	EPSD	TCGA;ICGC;COSMIC	20.411	Gain
CK1_CK1_CK1-A_CSNK1A1_ST	Q9BXL7	CARD11	P48729	CSNK1A1	S541	P536S	536	Missense	distal	-5	no	22.394	22.826	EPSD	TCGA;ICGC;COSMIC	20.411	Up-regulation
CK1_CK1_CK1-A_CSNK1A1_ST	Q9BXL7	CARD11	P48729	CSNK1A1	S541	I544T	544	Missense	distal	3	no	22.394	21.217	EPSD	TCGA;ICGC;COSMIC	20.411	Down-regulation
CK1_CK1_CK1-A_CSNK1A1_ST	Q9BXL7	CARD11	P48729	CSNK1A1	S593	D597N	597	Missense	distal	4	no	20.489	20.376	EPSD	TCGA;ICGC;COSMIC	20.411	Loss
CK1_CK1_CK1-A_CSNK1A1_ST	Q9BXL7	CARD11	P48729	CSNK1A1	S593	G594S	594	Missense	proximal	1	no	20.489	20.269	EPSD	TCGA;ICGC;COSMIC	20.411	Loss
CK1_CK1_CK1-A_CSNK1A1_ST	Q9BXL7	CARD11	P48729	CSNK1A1	S593	E588K	588	Missense	distal	-5	no	20.489	19.871	EPSD	TCGA;ICGC;COSMIC	20.411	Loss
CK1_CK1_CK1-A_CSNK1A1_ST	Q9BXL7	CARD11	P48729	CSNK1A1	S593	D592Y	592	Missense	proximal	-1	no	20.489	19.178	EPSD	TCGA;ICGC;COSMIC	20.411	Loss
CK1_CK1_CK1-A_CSNK1A1_ST	Q9BXL7	CARD11	P48729	CSNK1A1	S618	S614T	614	Missense	distal	-4	no	21.130	19.496	EPSD	TCGA;ICGC;COSMIC	20.411	Loss
CK1_CK1_CK1-A_CSNK1A1_ST	Q9BXL7	CARD11	P48729	CSNK1A1	S618	S621F	621	Missense	distal	3	no	21.130	18.669	EPSD	TCGA;ICGC;COSMIC	20.411	Loss
CK1_CK1_CK1-A_CSNK1A1_ST	Q9BXL7	CARD11	P48729	CSNK1A1	S621	E626K	626	Missense	distal	5	no	20.800	21.244	EPSD	TCGA;ICGC;COSMIC	20.411	Up-regulation
CK1_CK1_CK1-A_CSNK1A1_ST	Q9BXL7	CARD11	P48729	CSNK1A1	S621	S614T	614	Missense	distal	-7	no	20.800	20.351	EPSD	TCGA;ICGC;COSMIC	20.411	Loss
CK1_CK1_CK1-A_CSNK1A1_ST	Q9BXL7	CARD11	P48729	CSNK1A1	S621	S621F	621	Missense	central	0	yes	20.800	0.000	EPSD	TCGA;ICGC;COSMIC	20.411	Loss
CK1_CK1_CK1-A_CSNK1A1_ST	Q9BXL7	CARD11	P48729	CSNK1A1	S622	E626K	626	Missense	distal	4	no	22.741	22.551	EPSD	TCGA;ICGC;COSMIC	20.411	Down-regulation
CK1_CK1_CK1-A_CSNK1A1_ST	Q9BXL7	CARD11	P48729	CSNK1A1	S622	S621F	621	Missense	proximal	-1	no	22.741	22.038	EPSD	TCGA;ICGC;COSMIC	20.411	Down-regulation
CK1_CK1_CK1-A_CSNK1A1_ST	Q9BXL7	CARD11	P48729	CSNK1A1	S622	D629E	629	Missense	distal	7	no	22.741	22.654	EPSD	TCGA;ICGC;COSMIC	20.411	Down-regulation
CK1_CK1_CK1-A_CSNK1A1_ST	Q9BXL7	CARD11	P48729	CSNK1A1	S879	A877V	877	Missense	proximal	-2	no	23.417	22.020	EPSD	TCGA;ICGC;COSMIC	20.411	Down-regulation
CK1_CK1_CK1-A_CSNK1A1_ST	Q9BXL7	CARD11	P48729	CSNK1A1	S879	R884W	884	Missense	distal	5	no	23.417	23.691	EPSD	TCGA;ICGC;COSMIC	20.411	Up-regulation
CK1_CK1_CK1-A_CSNK1A1_ST	Q9BXL7	CARD11	P48729	CSNK1A1	S952	E947K	947	Missense	distal	-5	no	21.761	21.143	EPSD	TCGA;ICGC;COSMIC	20.411	Down-regulation
CK1_CK1_CK1-A_CSNK1A1_ST	Q9BXL7	CARD11	P48729	CSNK1A1	S952	E953K	953	Missense	proximal	1	no	21.761	21.301	EPSD	TCGA;ICGC;COSMIC	20.411	Down-regulation
CK1_CK1_CK1-A_CSNK1A1_ST	P18846	ATF1	P48729	CSNK1A1	S36	Q42H	42	Missense	distal	6	no	21.391	21.403	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	20.411	Up-regulation
CK1_CK1_CK1-A_CSNK1A1_ST	P18846	ATF1	P48729	CSNK1A1	S41	D46N	46	Missense	distal	5	no	23.501	23.747	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	20.411	Up-regulation
CK1_CK1_CK1-A_CSNK1A1_ST	P18846	ATF1	P48729	CSNK1A1	S41	S47T	47	Missense	distal	6	no	23.501	23.397	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	20.411	Down-regulation
CK1_CK1_CK1-A_CSNK1A1_ST	P18846	ATF1	P48729	CSNK1A1	S41	Q42H	42	Missense	proximal	1	no	23.501	23.075	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	20.411	Down-regulation
CK1_CK1_CK1-A_CSNK1A1_ST	P18846	ATF1	P48729	CSNK1A1	S47	D46N	46	Missense	proximal	-1	no	27.155	26.591	PhosphoSitePlus;EPSD	TCGA;ICGC;COSMIC	20.411	Down-regulation
CK1_CK1_CK1-A_CSNK1A1_ST	P18846	ATF1	P48729	CSNK1A1	S47	Q42H	42	Missense	distal	-5	no	27.155	25.860	PhosphoSitePlus;EPSD	TCGA;ICGC;COSMIC	20.411	Down-regulation
CK1_CK1_CK1-A_CSNK1A1_ST	P18846	ATF1	P48729	CSNK1A1	S50	D46N	46	Missense	distal	-4	no	24.340	20.603	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	20.411	Down-regulation
CK1_CK1_CK1-A_CSNK1A1_ST	P18846	ATF1	P48729	CSNK1A1	S50	S47T	47	Missense	distal	-3	no	24.340	20.576	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	20.411	Down-regulation
CK1_CK1_CK1-A_CSNK1A1_ST	Q9Y4G8	RAPGEF2	P48729	CSNK1A1	S933	R929Q	929	Missense	distal	-4	no	18.474	20.688	EPSD	TCGA;ICGC;COSMIC	20.411	Gain
CK1_CK1_CK1-A_CSNK1A1_ST	Q9Y4G8	RAPGEF2	P48729	CSNK1A1	S935	R929Q	929	Missense	distal	-6	no	21.391	21.580	EPSD	TCGA;ICGC;COSMIC	20.411	Up-regulation
CK1_CK1_CK1-A_CSNK1A1_ST	Q9Y4G8	RAPGEF2	P48729	CSNK1A1	S1095	L1088I	1088	Missense	distal	-7	no	21.168	22.187	EPSD	TCGA;ICGC;COSMIC;CCLE	20.411	Up-regulation
CK1_CK1_CK1-A_CSNK1A1_ST	Q9Y4G8	RAPGEF2	P48729	CSNK1A1	S1108	S1115C	1115	Missense	distal	7	no	21.052	21.204	EPSD	TCGA;ICGC;COSMIC	20.411	Up-regulation
CK1_CK1_CK1-A_CSNK1A1_ST	Q9Y4G8	RAPGEF2	P48729	CSNK1A1	S1153	R1151Q	1151	Missense	proximal	-2	no	22.514	23.021	EPSD	TCGA;ICGC;COSMIC	20.411	Up-regulation
CK1_CK1_CK1-A_CSNK1A1_ST	Q9Y4G8	RAPGEF2	P48729	CSNK1A1	S1153	S1152Y	1152	Missense	proximal	-1	no	22.514	21.629	EPSD	TCGA;ICGC;COSMIC	20.411	Down-regulation
CK1_CK1_CK1-A_CSNK1A1_ST	Q9Y4G8	RAPGEF2	P48729	CSNK1A1	S1153	S1158L	1158	Missense	distal	5	no	22.514	22.827	EPSD	TCGA;ICGC;COSMIC	20.411	Up-regulation
CK1_CK1_CK1-A_CSNK1A1_ST	Q9Y4G8	RAPGEF2	P48729	CSNK1A1	S1156	R1151Q	1151	Missense	distal	-5	no	21.524	22.321	EPSD	TCGA;ICGC;COSMIC	20.411	Up-regulation
CK1_CK1_CK1-A_CSNK1A1_ST	Q9Y4G8	RAPGEF2	P48729	CSNK1A1	S1156	V1163L	1163	Missense	distal	7	no	21.524	21.361	EPSD	TCGA;ICGC;COSMIC	20.411	Down-regulation
CK1_CK1_CK1-A_CSNK1A1_ST	Q9Y4G8	RAPGEF2	P48729	CSNK1A1	S1156	S1152Y	1152	Missense	distal	-4	no	21.524	18.972	EPSD	TCGA;ICGC;COSMIC	20.411	Loss
CK1_CK1_CK1-A_CSNK1A1_ST	Q9Y4G8	RAPGEF2	P48729	CSNK1A1	S1156	S1158L	1158	Missense	proximal	2	no	21.524	20.539	EPSD	TCGA;ICGC;COSMIC	20.411	Down-regulation
CK1_CK1_CK1-A_CSNK1A1_ST	Q9Y4G8	RAPGEF2	P48729	CSNK1A1	S1225	S1222F	1222	Missense	distal	-3	no	20.882	15.229	EPSD	TCGA;ICGC;COSMIC	20.411	Loss
CK1_CK1_CK1-A_CSNK1A1_ST	Q9Y4G8	RAPGEF2	P48729	CSNK1A1	S1225	T1219A	1219	Missense	distal	-6	no	20.882	20.355	EPSD	TCGA;ICGC;COSMIC	20.411	Loss
CK1_CK1_CK1-A_CSNK1A1_ST	Q9Y4G8	RAPGEF2	P48729	CSNK1A1	S1225	S1222Y	1222	Missense	distal	-3	no	20.882	14.906	EPSD	TCGA;ICGC;COSMIC	20.411	Loss
CK1_CK1_CK1-A_CSNK1A1_ST	Q9Y4G8	RAPGEF2	P48729	CSNK1A1	S1230	R1236C	1236	Missense	distal	6	no	23.223	22.991	EPSD	TCGA;ICGC;COSMIC;GDSC;CCLE	20.411	Down-regulation
CK1_CK1_CK1-A_CSNK1A1_ST	Q9Y4G8	RAPGEF2	P48729	CSNK1A1	S1238	R1236C	1236	Missense	proximal	-2	no	21.897	21.670	EPSD	TCGA;ICGC;COSMIC;GDSC;CCLE	20.411	Down-regulation
CK1_CK1_CK1-A_CSNK1A1_ST	Q9Y4G8	RAPGEF2	P48729	CSNK1A1	S1238	S1244I	1244	Missense	distal	6	no	21.897	21.895	EPSD	TCGA;ICGC;COSMIC	20.411	Down-regulation
CK1_CK1_CK1-A_CSNK1A1_ST	Q9Y4G8	RAPGEF2	P48729	CSNK1A1	S1238	G1245C	1245	Missense	distal	7	no	21.897	22.028	EPSD	TCGA;ICGC;COSMIC	20.411	Up-regulation
CK1_CK1_CK1-A_CSNK1A1_ST	Q9Y4G8	RAPGEF2	P48729	CSNK1A1	S1238	D1240H	1240	Missense	proximal	2	no	21.897	20.424	EPSD	TCGA;ICGC;COSMIC	20.411	Down-regulation
CK1_CK1_CK1-A_CSNK1A1_ST	Q9Y4G8	RAPGEF2	P48729	CSNK1A1	S1244	R1246S	1246	Missense	proximal	2	no	24.769	25.376	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	20.411	Up-regulation
CK1_CK1_CK1-A_CSNK1A1_ST	Q9Y4G8	RAPGEF2	P48729	CSNK1A1	S1244	S1244I	1244	Missense	central	0	yes	24.769	0.000	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	20.411	Loss
CK1_CK1_CK1-A_CSNK1A1_ST	Q9Y4G8	RAPGEF2	P48729	CSNK1A1	S1244	G1245C	1245	Missense	proximal	1	no	24.769	24.345	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	20.411	Down-regulation
CK1_CK1_CK1-A_CSNK1A1_ST	Q9Y4G8	RAPGEF2	P48729	CSNK1A1	S1244	D1240H	1240	Missense	distal	-4	no	24.769	19.701	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	20.411	Loss
CK1_CK1_CK1-A_CSNK1A1_ST	Q9Y4G8	RAPGEF2	P48729	CSNK1A1	S1248	R1246S	1246	Missense	proximal	-2	no	21.193	22.283	PhosphoSitePlus;EPSD	TCGA;ICGC;COSMIC	20.411	Up-regulation
CK1_CK1_CK1-A_CSNK1A1_ST	Q9Y4G8	RAPGEF2	P48729	CSNK1A1	S1248	C1252S	1252	Missense	distal	4	no	21.193	21.312	PhosphoSitePlus;EPSD	TCGA;ICGC;COSMIC	20.411	Up-regulation
CK1_CK1_CK1-A_CSNK1A1_ST	Q9Y4G8	RAPGEF2	P48729	CSNK1A1	S1248	S1244I	1244	Missense	distal	-4	no	21.193	18.994	PhosphoSitePlus;EPSD	TCGA;ICGC;COSMIC	20.411	Loss
CK1_CK1_CK1-A_CSNK1A1_ST	Q9Y4G8	RAPGEF2	P48729	CSNK1A1	S1248	G1245C	1245	Missense	distal	-3	no	21.193	18.552	PhosphoSitePlus;EPSD	TCGA;ICGC;COSMIC	20.411	Loss
CK1_CK1_CK1-A_CSNK1A1_ST	Q9Y4G8	RAPGEF2	P48729	CSNK1A1	S1251	R1246S	1246	Missense	distal	-5	no	25.680	26.551	EPSD	TCGA;ICGC;COSMIC	20.411	Up-regulation
CK1_CK1_CK1-A_CSNK1A1_ST	Q9Y4G8	RAPGEF2	P48729	CSNK1A1	S1251	C1252S	1252	Missense	proximal	1	no	25.680	25.884	EPSD	TCGA;ICGC;COSMIC	20.411	Up-regulation
CK1_CK1_CK1-A_CSNK1A1_ST	Q9Y4G8	RAPGEF2	P48729	CSNK1A1	S1251	S1244I	1244	Missense	distal	-7	no	25.680	26.018	EPSD	TCGA;ICGC;COSMIC	20.411	Up-regulation
CK1_CK1_CK1-A_CSNK1A1_ST	Q9Y4G8	RAPGEF2	P48729	CSNK1A1	S1251	G1245C	1245	Missense	distal	-6	no	25.680	24.686	EPSD	TCGA;ICGC;COSMIC	20.411	Down-regulation
CK1_CK1_CK1-A_CSNK1A1_ST	Q9Y4G8	RAPGEF2	P48729	CSNK1A1	S1251	D1258A	1258	Missense	distal	7	no	25.680	25.797	EPSD	TCGA;ICGC;COSMIC	20.411	Up-regulation
CK1_CK1_CK1-A_CSNK1A1_ST	Q9Y4G8	RAPGEF2	P48729	CSNK1A1	S1253	C1252S	1252	Missense	proximal	-1	no	19.311	20.491	EPSD	TCGA;ICGC;COSMIC	20.411	Gain
CK1_CK1_CK1-A_CSNK1A1_ST	Q9Y4G8	RAPGEF2	P48729	CSNK1A1	S1254	C1252S	1252	Missense	proximal	-2	no	22.407	23.724	EPSD	TCGA;ICGC;COSMIC	20.411	Up-regulation
CK1_CK1_CK1-A_CSNK1A1_ST	Q9Y4G8	RAPGEF2	P48729	CSNK1A1	S1254	D1258A	1258	Missense	distal	4	no	22.407	22.349	EPSD	TCGA;ICGC;COSMIC	20.411	Down-regulation
CK1_CK1_CK1-A_CSNK1A1_ST	Q9Y4G8	RAPGEF2	P48729	CSNK1A1	S1316	A1320T	1320	Missense	distal	4	no	27.746	27.735	EPSD	TCGA;ICGC	20.411	Down-regulation
CK1_CK1_CK1-A_CSNK1A1_ST	Q9Y4G8	RAPGEF2	P48729	CSNK1A1	S1316	Q1312K	1312	Missense	distal	-4	no	27.746	24.426	EPSD	TCGA;ICGC;COSMIC	20.411	Down-regulation
CK1_CK1_CK1-A_CSNK1A1_ST	Q9Y4G8	RAPGEF2	P48729	CSNK1A1	S1322	A1327V	1327	Missense	distal	5	no	21.479	21.511	EPSD	TCGA;ICGC;COSMIC	20.411	Up-regulation
CK1_CK1_CK1-A_CSNK1A1_ST	Q9Y4G8	RAPGEF2	P48729	CSNK1A1	S1322	A1320T	1320	Missense	proximal	-2	no	21.479	21.306	EPSD	TCGA;ICGC	20.411	Down-regulation
CK1_CK1_CK1-A_CSNK1A1_ST	Q9Y4G8	RAPGEF2	P48729	CSNK1A1	S1325	A1327V	1327	Missense	proximal	2	no	23.302	22.859	EPSD	TCGA;ICGC;COSMIC	20.411	Down-regulation
CK1_CK1_CK1-A_CSNK1A1_ST	Q9Y4G8	RAPGEF2	P48729	CSNK1A1	S1325	A1320T	1320	Missense	distal	-5	no	23.302	23.982	EPSD	TCGA;ICGC	20.411	Up-regulation
CK1_CK1_CK1-A_CSNK1A1_ST	Q9Y4G8	RAPGEF2	P48729	CSNK1A1	S1328	A1327V	1327	Missense	proximal	-1	no	20.464	19.862	EPSD	TCGA;ICGC;COSMIC	20.411	Loss
CK1_CK1_CK1-A_CSNK1A1_ST	Q9Y4G8	RAPGEF2	P48729	CSNK1A1	S1328	E1335D	1335	Missense	distal	7	no	20.464	20.550	EPSD	TCGA;ICGC	20.411	Up-regulation
CK1_CK1_CK1-A_CSNK1A1_ST	Q9Y4G8	RAPGEF2	P48729	CSNK1A1	S1337	E1335D	1335	Missense	proximal	-2	no	22.652	22.536	EPSD	TCGA;ICGC	20.411	Down-regulation
CK1_CK1_CK1-A_CSNK1A1_ST	P04637	TP53	P48729	CSNK1A1	S6	P4L	4	Missense	proximal	-2	no	22.651	21.668	EPSD	TCGA;ICGC;COSMIC	20.411	Down-regulation
CK1_CK1_CK1-A_CSNK1A1_ST	P04637	TP53	P48729	CSNK1A1	S9	P4L	4	Missense	distal	-5	no	20.768	20.572	EPSD	TCGA;ICGC;COSMIC	20.411	Down-regulation
CK1_CK1_CK1-A_CSNK1A1_ST	P04637	TP53	P48729	CSNK1A1	S46	D48N	48	Missense	proximal	2	no	20.672	19.478	EPSD	TCGA;ICGC;COSMIC;GDSC;CCLE	20.411	Loss
CK1_CK1_CK1-A_CSNK1A1_ST	P04637	TP53	P48729	CSNK1A1	S183	H179D	179	Missense	distal	-4	no	16.854	21.923	EPSD	TCGA;ICGC;COSMIC;GDSC;CCLE	20.411	Gain
CK1_CK1_CK1-A_CSNK1A1_ST	P04637	TP53	P48729	CSNK1A1	S183	H179Q	179	Missense	distal	-4	no	16.854	21.109	EPSD	TCGA;ICGC;COSMIC;GDSC;CCLE	20.411	Gain
CK1_CK1_CK1-A_CSNK1A1_ST	P17931	LGALS3	P48729	CSNK1A1	S12	G13V	13	Missense	proximal	1	no	22.212	21.978	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	20.411	Down-regulation
CK1_CK1_CK1-A_CSNK1A1_ST	Q13009	TIAM1	P48729	CSNK1A1	S63	R57Q	57	Missense	distal	-6	no	23.913	24.102	EPSD	TCGA;ICGC;COSMIC	20.411	Up-regulation
CK1_CK1_CK1-A_CSNK1A1_ST	Q13009	TIAM1	P48729	CSNK1A1	S219	A218V	218	Missense	proximal	-1	no	20.495	19.893	EPSD	TCGA	20.411	Loss
CK1_CK1_CK1-A_CSNK1A1_ST	Q13009	TIAM1	P48729	CSNK1A1	S219	P220T	220	Missense	proximal	1	no	20.495	20.351	EPSD	TCGA;ICGC;COSMIC	20.411	Loss
CK1_CK1_CK1-A_CSNK1A1_ST	Q13009	TIAM1	P48729	CSNK1A1	S219	P220L	220	Missense	proximal	1	no	20.495	20.605	EPSD	TCGA;ICGC;COSMIC	20.411	Up-regulation
CK1_CK1_CK1-A_CSNK1A1_ST	Q13009	TIAM1	P48729	CSNK1A1	S219	R217W	217	Missense	proximal	-2	no	20.495	21.042	EPSD	TCGA;ICGC;COSMIC	20.411	Up-regulation
CK1_CK1_CK1-A_CSNK1A1_ST	Q13009	TIAM1	P48729	CSNK1A1	S219	P220Q	220	Missense	proximal	1	no	20.495	20.629	EPSD	TCGA;ICGC;COSMIC	20.411	Up-regulation
CK1_CK1_CK1-A_CSNK1A1_ST	Q13009	TIAM1	P48729	CSNK1A1	S219	C226W	226	Missense	distal	7	no	20.495	20.825	EPSD	TCGA;ICGC;COSMIC	20.411	Up-regulation
CK1_CK1_CK1-A_CSNK1A1_ST	Q13009	TIAM1	P48729	CSNK1A1	S219	R221Q	221	Missense	proximal	2	no	20.495	20.786	EPSD	TCGA;ICGC;COSMIC	20.411	Up-regulation
CK1_CK1_CK1-A_CSNK1A1_ST	Q13009	TIAM1	P48729	CSNK1A1	S251	C257S	257	Missense	distal	6	no	20.260	20.685	EPSD	TCGA;ICGC;COSMIC	20.411	Gain
CK1_CK1_CK1-A_CSNK1A1_ST	Q13009	TIAM1	P48729	CSNK1A1	S311	A317T	317	Missense	distal	6	no	20.362	20.617	EPSD	TCGA;ICGC;COSMIC	20.411	Gain
CK1_CK1_CK1-A_CSNK1A1_ST	Q13009	TIAM1	P48729	CSNK1A1	S334	G335A	335	Missense	proximal	1	no	20.464	20.208	EPSD	TCGA;ICGC;COSMIC	20.411	Loss
CK1_CK1_CK1-A_CSNK1A1_ST	Q13009	TIAM1	P48729	CSNK1A1	S334	E330K	330	Missense	distal	-4	no	20.464	16.767	EPSD	TCGA;ICGC;COSMIC	20.411	Loss
CK1_CK1_CK1-A_CSNK1A1_ST	Q13009	TIAM1	P48729	CSNK1A1	S372	D369N	369	Missense	distal	-3	no	20.561	15.281	EPSD	TCGA;ICGC;COSMIC	20.411	Loss
CK1_CK1_CK1-A_CSNK1A1_ST	Q13009	TIAM1	P48729	CSNK1A1	S372	A378V	378	Missense	distal	6	no	20.561	20.459	EPSD	TCGA;ICGC;COSMIC	20.411	Down-regulation
CK1_CK1_CK1-A_CSNK1A1_ST	Q13009	TIAM1	P48729	CSNK1A1	S372	G367S	367	Missense	distal	-5	no	20.561	20.268	EPSD	TCGA;ICGC;COSMIC	20.411	Loss
CK1_CK1_CK1-A_CSNK1A1_ST	Q13009	TIAM1	P48729	CSNK1A1	S372	G371D	371	Missense	proximal	-1	no	20.561	20.288	EPSD	TCGA;ICGC	20.411	Loss
CK1_CK1_CK1-A_CSNK1A1_ST	Q13009	TIAM1	P48729	CSNK1A1	S373	D369N	369	Missense	distal	-4	no	23.499	19.761	EPSD	TCGA;ICGC;COSMIC	20.411	Loss
CK1_CK1_CK1-A_CSNK1A1_ST	Q13009	TIAM1	P48729	CSNK1A1	S373	A378V	378	Missense	distal	5	no	23.499	23.531	EPSD	TCGA;ICGC;COSMIC	20.411	Up-regulation
CK1_CK1_CK1-A_CSNK1A1_ST	Q13009	TIAM1	P48729	CSNK1A1	S373	R380H	380	Missense	distal	7	no	23.499	23.625	EPSD	TCGA;ICGC;COSMIC	20.411	Up-regulation
CK1_CK1_CK1-A_CSNK1A1_ST	Q13009	TIAM1	P48729	CSNK1A1	S373	G367S	367	Missense	distal	-6	no	23.499	23.358	EPSD	TCGA;ICGC;COSMIC	20.411	Down-regulation
CK1_CK1_CK1-A_CSNK1A1_ST	Q13009	TIAM1	P48729	CSNK1A1	S373	G371D	371	Missense	proximal	-2	no	23.499	23.531	EPSD	TCGA;ICGC	20.411	Up-regulation
CK1_CK1_CK1-A_CSNK1A1_ST	Q13009	TIAM1	P48729	CSNK1A1	S374	D369N	369	Missense	distal	-5	no	23.810	23.560	EPSD	TCGA;ICGC;COSMIC	20.411	Down-regulation
CK1_CK1_CK1-A_CSNK1A1_ST	Q13009	TIAM1	P48729	CSNK1A1	S374	A378V	378	Missense	distal	4	no	23.810	23.740	EPSD	TCGA;ICGC;COSMIC	20.411	Down-regulation
CK1_CK1_CK1-A_CSNK1A1_ST	Q13009	TIAM1	P48729	CSNK1A1	S374	R380H	380	Missense	distal	6	no	23.810	23.739	EPSD	TCGA;ICGC;COSMIC	20.411	Down-regulation
CK1_CK1_CK1-A_CSNK1A1_ST	Q13009	TIAM1	P48729	CSNK1A1	S374	G367S	367	Missense	distal	-7	no	23.810	22.758	EPSD	TCGA;ICGC;COSMIC	20.411	Down-regulation
CK1_CK1_CK1-A_CSNK1A1_ST	Q13009	TIAM1	P48729	CSNK1A1	S374	G371D	371	Missense	distal	-3	no	23.810	25.873	EPSD	TCGA;ICGC	20.411	Up-regulation
CK1_CK1_CK1-A_CSNK1A1_ST	Q13009	TIAM1	P48729	CSNK1A1	S483	S489C	489	Missense	distal	6	no	25.529	25.104	EPSD	TCGA;ICGC;COSMIC	20.411	Down-regulation
CK1_CK1_CK1-A_CSNK1A1_ST	Q13009	TIAM1	P48729	CSNK1A1	S483	D480N	480	Missense	distal	-3	no	25.529	20.249	EPSD	TCGA;ICGC;COSMIC;CCLE	20.411	Loss
CK1_CK1_CK1-A_CSNK1A1_ST	Q13009	TIAM1	P48729	CSNK1A1	S483	E478Q	478	Missense	distal	-5	no	25.529	26.097	EPSD	TCGA;ICGC;COSMIC	20.411	Up-regulation
CK1_CK1_CK1-A_CSNK1A1_ST	Q13009	TIAM1	P48729	CSNK1A1	S483	G484W	484	Missense	proximal	1	no	25.529	24.916	EPSD	TCGA;ICGC;COSMIC	20.411	Down-regulation
CK1_CK1_CK1-A_CSNK1A1_ST	Q13009	TIAM1	P48729	CSNK1A1	S483	G481S	481	Missense	proximal	-2	no	25.529	25.678	EPSD	TCGA;ICGC;COSMIC	20.411	Up-regulation
CK1_CK1_CK1-A_CSNK1A1_ST	Q13009	TIAM1	P48729	CSNK1A1	S695	R690M	690	Missense	distal	-5	no	19.422	20.878	EPSD	TCGA;ICGC;COSMIC	20.411	Gain
CK1_CK1_CK1-A_CSNK1A1_ST	Q13009	TIAM1	P48729	CSNK1A1	S726	E721K	721	Missense	distal	-5	no	21.784	21.166	EPSD	TCGA;ICGC;COSMIC	20.411	Down-regulation
CK1_CK1_CK1-A_CSNK1A1_ST	Q13009	TIAM1	P48729	CSNK1A1	S726	K724N	724	Missense	proximal	-2	no	21.784	20.857	EPSD	TCGA;ICGC;COSMIC	20.411	Down-regulation
CK1_CK1_CK1-A_CSNK1A1_ST	Q13009	TIAM1	P48729	CSNK1A1	S726	S726Y	726	Missense	central	0	yes	21.784	0.000	EPSD	TCGA;ICGC;COSMIC	20.411	Loss
CK1_CK1_CK1-A_CSNK1A1_ST	Q13009	TIAM1	P48729	CSNK1A1	S989	P984S	984	Missense	distal	-5	no	20.497	20.930	EPSD	TCGA;COSMIC	20.411	Up-regulation
CK1_CK1_CK1-A_CSNK1A1_ST	Q13009	TIAM1	P48729	CSNK1A1	S989	S988F	988	Missense	proximal	-1	no	20.497	19.795	EPSD	TCGA;COSMIC	20.411	Loss
CK1_CK1_CK1-A_CSNK1A1_ST	Q13009	TIAM1	P48729	CSNK1A1	T992	S988F	988	Missense	distal	-4	no	21.646	19.996	EPSD	TCGA;COSMIC	20.411	Loss
CK1_CK1_CK1-A_CSNK1A1_ST	Q13009	TIAM1	P48729	CSNK1A1	S1020	S1018N	1018	Missense	proximal	-2	no	23.833	21.592	EPSD	TCGA;COSMIC	20.411	Down-regulation
CK1_CK1_CK1-A_CSNK1A1_ST	Q13009	TIAM1	P48729	CSNK1A1	S1020	P1021T	1021	Missense	proximal	1	no	23.833	23.689	EPSD	TCGA;COSMIC	20.411	Down-regulation
CK1_CK1_CK1-A_CSNK1A1_ST	Q13009	TIAM1	P48729	CSNK1A1	S1020	G1026V	1026	Missense	distal	6	no	23.833	23.354	EPSD	TCGA;ICGC;COSMIC	20.411	Down-regulation
CK1_CK1_CK1-A_CSNK1A1_ST	Q12968	NFATC3	P48729	CSNK1A1	S98	G101R	101	Missense	distal	3	no	21.252	18.361	EPSD	TCGA;ICGC;COSMIC	20.411	Loss
CK1_CK1_CK1-A_CSNK1A1_ST	Q12968	NFATC3	P48729	CSNK1A1	S98	P103L	103	Missense	distal	5	no	21.252	21.316	EPSD	TCGA;ICGC	20.411	Up-regulation
CK1_CK1_CK1-A_CSNK1A1_ST	Q12968	NFATC3	P48729	CSNK1A1	S177	F176L	176	Missense	proximal	-1	no	22.266	22.694	EPSD	TCGA;ICGC;COSMIC	20.411	Up-regulation
CK1_CK1_CK1-A_CSNK1A1_ST	Q12968	NFATC3	P48729	CSNK1A1	S177	D178N	178	Missense	proximal	1	no	22.266	22.036	EPSD	TCGA;ICGC;COSMIC	20.411	Down-regulation
CK1_CK1_CK1-A_CSNK1A1_ST	Q12968	NFATC3	P48729	CSNK1A1	S181	F176L	176	Missense	distal	-5	no	22.963	24.234	EPSD	TCGA;ICGC;COSMIC	20.411	Up-regulation
CK1_CK1_CK1-A_CSNK1A1_ST	Q12968	NFATC3	P48729	CSNK1A1	S181	D178N	178	Missense	distal	-3	no	22.963	17.683	EPSD	TCGA;ICGC;COSMIC	20.411	Loss
CK1_CK1_CK1-A_CSNK1A1_ST	Q12968	NFATC3	P48729	CSNK1A1	S184	D191N	191	Missense	distal	7	no	21.439	21.523	EPSD	TCGA;ICGC;COSMIC	20.411	Up-regulation
CK1_CK1_CK1-A_CSNK1A1_ST	Q12968	NFATC3	P48729	CSNK1A1	S184	D178N	178	Missense	distal	-6	no	21.439	20.159	EPSD	TCGA;ICGC;COSMIC	20.411	Loss
CK1_CK1_CK1-A_CSNK1A1_ST	Q12968	NFATC3	P48729	CSNK1A1	T204	R202Q	202	Missense	proximal	-2	no	20.405	20.912	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	20.411	Gain
CK1_CK1_CK1-A_CSNK1A1_ST	Q12968	NFATC3	P48729	CSNK1A1	S269	R266T	266	Missense	distal	-3	no	20.697	21.158	EPSD	TCGA;ICGC;COSMIC	20.411	Up-regulation
CK1_CK1_CK1-A_CSNK1A1_ST	Q12968	NFATC3	P48729	CSNK1A1	S269	P270S	270	Missense	proximal	1	no	20.697	20.544	EPSD	TCGA;ICGC;COSMIC	20.411	Down-regulation
CK1_CK1_CK1-A_CSNK1A1_ST	Q12968	NFATC3	P48729	CSNK1A1	S269	R275M	275	Missense	distal	6	no	20.697	20.968	EPSD	TCGA;ICGC;COSMIC	20.411	Up-regulation
CK1_CK1_CK1-A_CSNK1A1_ST	Q12968	NFATC3	P48729	CSNK1A1	S742	S736L	736	Missense	distal	-6	no	21.943	21.049	EPSD	TCGA;ICGC;COSMIC	20.411	Down-regulation
CK1_CK1_CK1-A_CSNK1A1_ST	Q12968	NFATC3	P48729	CSNK1A1	S742	Q744H	744	Missense	proximal	2	no	21.943	20.926	EPSD	TCGA;ICGC;COSMIC	20.411	Down-regulation
CK1_CK1_CK1-A_CSNK1A1_ST	Q12968	NFATC3	P48729	CSNK1A1	S1048	G1052E	1052	Missense	distal	4	no	23.341	23.417	EPSD	TCGA;ICGC;COSMIC	20.411	Up-regulation
CK1_CK1_CK1-A_CSNK1A1_ST	O60716	CTNND1	P48729	CSNK1A1	T134	R135Q	135	Missense	proximal	1	no	21.402	21.743	EPSD	TCGA;COSMIC	20.411	Up-regulation
CK1_CK1_CK1-A_CSNK1A1_ST	O60716	CTNND1	P48729	CSNK1A1	T134	V141A	141	Missense	distal	7	no	21.402	21.283	EPSD	TCGA;COSMIC	20.411	Down-regulation
CK1_CK1_CK1-A_CSNK1A1_ST	O60716	CTNND1	P48729	CSNK1A1	T134	R136H	136	Missense	proximal	2	no	21.402	20.677	EPSD	TCGA;COSMIC	20.411	Down-regulation
CK1_CK1_CK1-A_CSNK1A1_ST	O60716	CTNND1	P48729	CSNK1A1	S169	L163W	163	Missense	distal	-6	no	20.796	21.022	EPSD	TCGA;COSMIC	20.411	Up-regulation
CK1_CK1_CK1-A_CSNK1A1_ST	O60716	CTNND1	P48729	CSNK1A1	S252	R249W	249	Missense	distal	-3	no	20.799	24.069	EPSD	TCGA;COSMIC	20.411	Up-regulation
CK1_CK1_CK1-A_CSNK1A1_ST	O60716	CTNND1	P48729	CSNK1A1	S288	D293N	293	Missense	distal	5	no	22.680	22.926	EPSD	TCGA;COSMIC	20.411	Up-regulation
CK1_CK1_CK1-A_CSNK1A1_ST	O60716	CTNND1	P48729	CSNK1A1	S288	G290C	290	Missense	proximal	2	no	22.680	21.350	EPSD	TCGA;COSMIC	20.411	Down-regulation
CK1_CK1_CK1-A_CSNK1A1_ST	O60716	CTNND1	P48729	CSNK1A1	S312	S312C	312	Missense	central	0	yes	22.413	0.000	EPSD	TCGA;COSMIC	20.411	Loss
CK1_CK1_CK1-A_CSNK1A1_ST	O60716	CTNND1	P48729	CSNK1A1	S312	R315G	315	Missense	distal	3	no	22.413	25.304	EPSD	TCGA;COSMIC	20.411	Up-regulation
CK1_CK1_CK1-A_CSNK1A1_ST	O60716	CTNND1	P48729	CSNK1A1	S312	L318R	318	Missense	distal	6	no	22.413	22.360	EPSD	TCGA;COSMIC	20.411	Down-regulation
CK1_CK1_CK1-A_CSNK1A1_ST	O60716	CTNND1	P48729	CSNK1A1	S312	R317H	317	Missense	distal	5	no	22.413	22.476	EPSD	TCGA;COSMIC	20.411	Up-regulation
CK1_CK1_CK1-A_CSNK1A1_ST	O60716	CTNND1	P48729	CSNK1A1	S349	R354H	354	Missense	distal	5	no	21.809	21.873	EPSD	TCGA;COSMIC	20.411	Up-regulation
CK1_CK1_CK1-A_CSNK1A1_ST	O60716	CTNND1	P48729	CSNK1A1	S943	L944V	944	Missense	proximal	1	no	20.801	20.525	EPSD	TCGA;COSMIC	20.411	Down-regulation
CK1_CK1_CK1-A_CSNK1A1_ST	O60716	CTNND1	P48729	CSNK1A1	S943	E939K	939	Missense	distal	-4	no	20.801	17.104	EPSD	TCGA;COSMIC	20.411	Loss
CK1_CK1_CK1-A_CSNK1A1_ST	Q6IE81	JADE1	P48729	CSNK1A1	S13	G17D	17	Missense	distal	4	no	21.288	21.292	EPSD	TCGA;COSMIC;GDSC	20.411	Up-regulation
CK1_CK1_CK1-A_CSNK1A1_ST	Q6IE81	JADE1	P48729	CSNK1A1	S13	S18N	18	Missense	distal	5	no	21.288	21.709	EPSD	TCGA	20.411	Up-regulation
CK1_CK1_CK1-A_CSNK1A1_ST	Q6IE81	JADE1	P48729	CSNK1A1	S18	G17D	17	Missense	proximal	-1	no	22.261	21.988	PhosphoSitePlus;EPSD	TCGA;COSMIC;GDSC	20.411	Down-regulation
CK1_CK1_CK1-A_CSNK1A1_ST	Q6IE81	JADE1	P48729	CSNK1A1	S18	S18N	18	Missense	central	0	yes	22.261	0.000	PhosphoSitePlus;EPSD	TCGA	20.411	Loss
CK1_CK1_CK1-A_CSNK1A1_ST	Q6IE81	JADE1	P48729	CSNK1A1	S547	S544C	544	Missense	distal	-3	no	23.164	18.831	EPSD	TCGA;COSMIC	20.411	Loss
CK1_CK1_CK1-A_CSNK1A1_ST	Q6IE81	JADE1	P48729	CSNK1A1	S548	S544C	544	Missense	distal	-4	no	22.594	19.895	EPSD	TCGA;COSMIC	20.411	Loss
CK1_CK1_CK1-A_CSNK1A1_ST	Q6IE81	JADE1	P48729	CSNK1A1	S549	S544C	544	Missense	distal	-5	no	23.961	22.657	EPSD	TCGA;COSMIC	20.411	Down-regulation
CK1_CK1_CK1-A_CSNK1A1_ST	Q6IE81	JADE1	P48729	CSNK1A1	S550	S544C	544	Missense	distal	-6	no	26.552	25.698	EPSD	TCGA;COSMIC	20.411	Down-regulation
CK1_CK1_CK1-A_CSNK1A1_ST	Q6IE81	JADE1	P48729	CSNK1A1	S812	K819N	819	Missense	distal	7	no	21.354	21.395	EPSD	TCGA;COSMIC	20.411	Up-regulation
CK1_CK1_CK1-A_CSNK1A1_ST	Q6IE81	JADE1	P48729	CSNK1A1	S814	K819N	819	Missense	distal	5	no	20.867	20.877	EPSD	TCGA;COSMIC	20.411	Up-regulation
CK1_CK1_CK1-A_CSNK1A1_ST	P56817	BACE1	P48729	CSNK1A1	S59	E62G	62	Missense	distal	3	no	22.859	22.725	EPSD	TCGA;ICGC;COSMIC	20.411	Down-regulation
CK1_CK1_CK1-A_CSNK1A1_ST	Q9NRF8	CTPS2	P48729	CSNK1A1	S279	L282I	282	Missense	distal	3	no	19.835	22.331	EPSD	TCGA;ICGC;COSMIC	20.411	Gain
CK1_CK1_CK1-A_CSNK1A1_ST	Q9NRF8	CTPS2	P48729	CSNK1A1	S279	L272M	272	Missense	distal	-7	no	19.835	20.414	EPSD	TCGA;ICGC;COSMIC	20.411	Gain
CK1_CK1_CK1-A_CSNK1A1_ST	P12830	CDH1	P48729	CSNK1A1	S770	L776M	776	Missense	distal	6	no	20.520	20.738	EPSD	TCGA;COSMIC	20.411	Up-regulation
CK1_CK1_CK1-A_CSNK1A1_ST	P12830	CDH1	P48729	CSNK1A1	S838	E841K	841	Missense	distal	3	no	23.165	19.035	EPSD	TCGA;COSMIC	20.411	Loss
CK1_CK1_CK1-A_CSNK1A1_ST	P12830	CDH1	P48729	CSNK1A1	S840	E841K	841	Missense	proximal	1	no	23.761	23.302	EPSD	TCGA;COSMIC	20.411	Down-regulation
CK1_CK1_CK1-A_CSNK1A1_ST	P12830	CDH1	P48729	CSNK1A1	S844	S850F	850	Missense	distal	6	no	24.956	24.378	PhosphoSitePlus	TCGA;COSMIC	20.411	Down-regulation
CK1_CK1_CK1-A_CSNK1A1_ST	P12830	CDH1	P48729	CSNK1A1	S844	E841K	841	Missense	distal	-3	no	24.956	21.036	PhosphoSitePlus	TCGA;COSMIC	20.411	Down-regulation
CK1_CK1_CK1-A_CSNK1A1_ST	P12830	CDH1	P48729	CSNK1A1	S850	S850F	850	Missense	central	0	yes	24.084	0.000	EPSD	TCGA;COSMIC	20.411	Loss
CK1_CK1_CK1-A_CSNK1A1_ST	P12830	CDH1	P48729	CSNK1A1	S853	S850F	850	Missense	distal	-3	no	25.072	19.420	EPSD	TCGA;COSMIC	20.411	Loss
CK1_CK1_CK1-A_CSNK1A1_ST	P51532	SMARCA4	P48729	CSNK1A1	S38	G33D	33	Missense	distal	-5	no	24.806	24.591	EPSD	TCGA;ICGC;COSMIC	20.411	Down-regulation
CK1_CK1_CK1-A_CSNK1A1_ST	P51532	SMARCA4	P48729	CSNK1A1	S111	P109L	109	Missense	proximal	-2	no	20.572	19.589	EPSD	TCGA;ICGC;COSMIC	20.411	Loss
CK1_CK1_CK1-A_CSNK1A1_ST	P51532	SMARCA4	P48729	CSNK1A1	S131	V134I	134	Missense	distal	3	no	20.285	21.614	EPSD	TCGA;ICGC;COSMIC	20.411	Gain
CK1_CK1_CK1-A_CSNK1A1_ST	P51532	SMARCA4	P48729	CSNK1A1	S147	S141L	141	Missense	distal	-6	no	21.551	20.657	EPSD	TCGA;ICGC;COSMIC	20.411	Down-regulation
CK1_CK1_CK1-A_CSNK1A1_ST	P51532	SMARCA4	P48729	CSNK1A1	S147	G148V	148	Missense	proximal	1	no	21.551	21.317	EPSD	TCGA;ICGC;COSMIC	20.411	Down-regulation
CK1_CK1_CK1-A_CSNK1A1_ST	P51532	SMARCA4	P48729	CSNK1A1	S147	S140Y	140	Missense	distal	-7	no	21.551	20.082	EPSD	TCGA;ICGC;COSMIC	20.411	Loss
CK1_CK1_CK1-A_CSNK1A1_ST	P51532	SMARCA4	P48729	CSNK1A1	S147	M145L	145	Missense	proximal	-2	no	21.551	19.967	EPSD	TCGA;ICGC;COSMIC	20.411	Loss
CK1_CK1_CK1-A_CSNK1A1_ST	P51532	SMARCA4	P48729	CSNK1A1	S147	G151S	151	Missense	distal	4	no	21.551	21.521	EPSD	TCGA;ICGC;COSMIC	20.411	Down-regulation
CK1_CK1_CK1-A_CSNK1A1_ST	P51532	SMARCA4	P48729	CSNK1A1	S660	E665D	665	Missense	distal	5	no	27.117	27.325	EPSD	TCGA	20.411	Up-regulation
CK1_CK1_CK1-A_CSNK1A1_ST	P51532	SMARCA4	P48729	CSNK1A1	S662	E669K	669	Missense	distal	7	no	21.031	21.160	EPSD	TCGA;ICGC;COSMIC	20.411	Up-regulation
CK1_CK1_CK1-A_CSNK1A1_ST	P51532	SMARCA4	P48729	CSNK1A1	S662	E665D	665	Missense	distal	3	no	21.031	21.170	EPSD	TCGA	20.411	Up-regulation
CK1_CK1_CK1-A_CSNK1A1_ST	P51532	SMARCA4	P48729	CSNK1A1	S695	E700K	700	Missense	distal	5	no	20.891	21.336	EPSD	TCGA;ICGC;COSMIC	20.411	Up-regulation
CK1_CK1_CK1-A_CSNK1A1_ST	P51532	SMARCA4	P48729	CSNK1A1	S695	D694Y	694	Missense	proximal	-1	no	20.891	19.580	EPSD	TCGA;ICGC;COSMIC	20.411	Loss
CK1_CK1_CK1-A_CSNK1A1_ST	P51532	SMARCA4	P48729	CSNK1A1	S695	V698I	698	Missense	distal	3	no	20.891	22.220	EPSD	TCGA;ICGC;COSMIC	20.411	Up-regulation
CK1_CK1_CK1-A_CSNK1A1_ST	P51532	SMARCA4	P48729	CSNK1A1	S695	P691A	691	Missense	distal	-4	no	20.891	21.983	EPSD	TCGA;ICGC	20.411	Up-regulation
CK1_CK1_CK1-A_CSNK1A1_ST	P51532	SMARCA4	P48729	CSNK1A1	S699	E700K	700	Missense	proximal	1	no	25.806	25.346	EPSD	TCGA;ICGC;COSMIC	20.411	Down-regulation
CK1_CK1_CK1-A_CSNK1A1_ST	P51532	SMARCA4	P48729	CSNK1A1	S699	D694Y	694	Missense	distal	-5	no	25.806	23.781	EPSD	TCGA;ICGC;COSMIC	20.411	Down-regulation
CK1_CK1_CK1-A_CSNK1A1_ST	P51532	SMARCA4	P48729	CSNK1A1	S699	V698I	698	Missense	proximal	-1	no	25.806	27.296	EPSD	TCGA;ICGC;COSMIC	20.411	Up-regulation
CK1_CK1_CK1-A_CSNK1A1_ST	P51532	SMARCA4	P48729	CSNK1A1	S746	R741K	741	Missense	distal	-5	no	21.090	20.701	EPSD	TCGA;ICGC;COSMIC	20.411	Down-regulation
CK1_CK1_CK1-A_CSNK1A1_ST	P51532	SMARCA4	P48729	CSNK1A1	S746	V742A	742	Missense	distal	-4	no	21.090	22.274	EPSD	TCGA;ICGC;COSMIC	20.411	Up-regulation
CK1_CK1_CK1-A_CSNK1A1_ST	P51532	SMARCA4	P48729	CSNK1A1	S1238	R1243W	1243	Missense	distal	5	no	22.517	22.790	EPSD	TCGA;ICGC;COSMIC	20.411	Up-regulation
CK1_CK1_CK1-A_CSNK1A1_ST	P51532	SMARCA4	P48729	CSNK1A1	S1238	A1231T	1231	Missense	distal	-7	no	22.517	21.545	EPSD	TCGA	20.411	Down-regulation
CK1_CK1_CK1-A_CSNK1A1_ST	P51532	SMARCA4	P48729	CSNK1A1	S1238	R1244P	1244	Missense	distal	6	no	22.517	22.484	EPSD	TCGA;ICGC;COSMIC	20.411	Down-regulation
CK1_CK1_CK1-A_CSNK1A1_ST	P51532	SMARCA4	P48729	CSNK1A1	S1238	F1234L	1234	Missense	distal	-4	no	22.517	20.360	EPSD	TCGA;ICGC;COSMIC	20.411	Loss
CK1_CK1_CK1-A_CSNK1A1_ST	P51532	SMARCA4	P48729	CSNK1A1	S1238	G1232S	1232	Missense	distal	-6	no	22.517	22.376	EPSD	TCGA;ICGC;COSMIC;GDSC;CCLE	20.411	Down-regulation
CK1_CK1_CK1-A_CSNK1A1_ST	P51532	SMARCA4	P48729	CSNK1A1	S1238	R1244G	1244	Missense	distal	6	no	22.517	22.728	EPSD	TCGA;ICGC;COSMIC	20.411	Up-regulation
CK1_CK1_CK1-A_CSNK1A1_ST	P51532	SMARCA4	P48729	CSNK1A1	S1238	G1232V	1232	Missense	distal	-6	no	22.517	21.210	EPSD	TCGA;ICGC;COSMIC	20.411	Down-regulation
CK1_CK1_CK1-A_CSNK1A1_ST	P51532	SMARCA4	P48729	CSNK1A1	S1238	E1242K	1242	Missense	distal	4	no	22.517	22.327	EPSD	TCGA;ICGC;COSMIC	20.411	Down-regulation
CK1_CK1_CK1-A_CSNK1A1_ST	P51532	SMARCA4	P48729	CSNK1A1	S1239	R1243W	1243	Missense	distal	4	no	21.136	20.860	EPSD	TCGA;ICGC;COSMIC	20.411	Down-regulation
CK1_CK1_CK1-A_CSNK1A1_ST	P51532	SMARCA4	P48729	CSNK1A1	S1239	R1244P	1244	Missense	distal	5	no	21.136	20.974	EPSD	TCGA;ICGC;COSMIC	20.411	Down-regulation
CK1_CK1_CK1-A_CSNK1A1_ST	P51532	SMARCA4	P48729	CSNK1A1	S1239	F1234L	1234	Missense	distal	-5	no	21.136	22.407	EPSD	TCGA;ICGC;COSMIC	20.411	Up-regulation
CK1_CK1_CK1-A_CSNK1A1_ST	P51532	SMARCA4	P48729	CSNK1A1	S1239	G1232S	1232	Missense	distal	-7	no	21.136	20.083	EPSD	TCGA;ICGC;COSMIC;GDSC;CCLE	20.411	Loss
CK1_CK1_CK1-A_CSNK1A1_ST	P51532	SMARCA4	P48729	CSNK1A1	S1239	R1244G	1244	Missense	distal	5	no	21.136	21.038	EPSD	TCGA;ICGC;COSMIC	20.411	Down-regulation
CK1_CK1_CK1-A_CSNK1A1_ST	P51532	SMARCA4	P48729	CSNK1A1	S1239	G1232V	1232	Missense	distal	-7	no	21.136	18.371	EPSD	TCGA;ICGC;COSMIC	20.411	Loss
CK1_CK1_CK1-A_CSNK1A1_ST	P51532	SMARCA4	P48729	CSNK1A1	S1239	E1242K	1242	Missense	distal	3	no	21.136	17.006	EPSD	TCGA;ICGC;COSMIC	20.411	Loss
CK1_CK1_CK1-A_CSNK1A1_ST	P51532	SMARCA4	P48729	CSNK1A1	S1421	S1422F	1422	Missense	proximal	1	no	20.493	20.437	EPSD	TCGA;ICGC;COSMIC	20.411	Down-regulation
CK1_CK1_CK1-A_CSNK1A1_ST	P51532	SMARCA4	P48729	CSNK1A1	S1421	D1418N	1418	Missense	distal	-3	no	20.493	15.213	EPSD	TCGA;COSMIC	20.411	Loss
CK1_CK1_CK1-A_CSNK1A1_ST	P51532	SMARCA4	P48729	CSNK1A1	S1421	P1424S	1424	Missense	distal	3	no	20.493	24.758	EPSD	TCGA;COSMIC	20.411	Up-regulation
CK1_CK1_CK1-A_CSNK1A1_ST	P51532	SMARCA4	P48729	CSNK1A1	S1575	D1568N	1568	Missense	distal	-7	no	27.501	27.444	EPSD	TCGA;COSMIC	20.411	Down-regulation
CK1_CK1_CK1-A_CSNK1A1_ST	P51532	SMARCA4	P48729	CSNK1A1	S1575	E1582K	1582	Missense	distal	7	no	27.501	27.630	EPSD	TCGA;COSMIC	20.411	Up-regulation
CK1_CK1_CK1-A_CSNK1A1_ST	P51532	SMARCA4	P48729	CSNK1A1	S1586	R1591W	1591	Missense	distal	5	no	24.243	24.517	EPSD	TCGA	20.411	Up-regulation
CK1_CK1_CK1-A_CSNK1A1_ST	P51532	SMARCA4	P48729	CSNK1A1	S1586	S1588F	1588	Missense	proximal	2	no	24.243	23.221	EPSD	TCGA;COSMIC	20.411	Down-regulation
CK1_CK1_CK1-A_CSNK1A1_ST	P51532	SMARCA4	P48729	CSNK1A1	S1586	E1582K	1582	Missense	distal	-4	no	24.243	20.546	EPSD	TCGA;COSMIC	20.411	Down-regulation
CK1_CK1_CK1-A_CSNK1A1_ST	P51532	SMARCA4	P48729	CSNK1A1	S1588	R1591W	1591	Missense	distal	3	no	21.835	22.623	EPSD	TCGA	20.411	Up-regulation
CK1_CK1_CK1-A_CSNK1A1_ST	P51532	SMARCA4	P48729	CSNK1A1	S1588	S1588F	1588	Missense	central	0	yes	21.835	0.000	EPSD	TCGA;COSMIC	20.411	Loss
CK1_CK1_CK1-A_CSNK1A1_ST	P51532	SMARCA4	P48729	CSNK1A1	S1588	E1582K	1582	Missense	distal	-6	no	21.835	21.557	EPSD	TCGA;COSMIC	20.411	Down-regulation
CK1_CK1_CK1-A_CSNK1A1_ST	P16220	CREB1	P48729	CSNK1A1	S111	D116G	116	Missense	distal	5	no	24.754	24.891	PhosphoSitePlus;EPSD	TCGA;COSMIC	20.411	Up-regulation
CK1_CK1_CK1-A_CSNK1A1_ST	P16220	CREB1	P48729	CSNK1A1	S111	Q112H	112	Missense	proximal	1	no	24.754	24.327	PhosphoSitePlus;EPSD	TCGA;COSMIC	20.411	Down-regulation
CK1_CK1_CK1-A_CSNK1A1_ST	P16220	CREB1	P48729	CSNK1A1	S114	D116G	116	Missense	proximal	2	no	26.239	26.443	EPSD;PhosphoSitePlus	TCGA;COSMIC	20.411	Up-regulation
CK1_CK1_CK1-A_CSNK1A1_ST	P16220	CREB1	P48729	CSNK1A1	S114	Q112H	112	Missense	proximal	-2	no	26.239	24.111	EPSD;PhosphoSitePlus	TCGA;COSMIC	20.411	Down-regulation
CK1_CK1_CK1-A_CSNK1A1_ST	P16220	CREB1	P48729	CSNK1A1	S117	D116G	116	Missense	proximal	-1	no	21.395	21.668	EPSD	TCGA;COSMIC	20.411	Up-regulation
CK1_CK1_CK1-A_CSNK1A1_ST	P16220	CREB1	P48729	CSNK1A1	S117	Q112H	112	Missense	distal	-5	no	21.395	20.100	EPSD	TCGA;COSMIC	20.411	Loss
CK1_CK1_CK1-A_CSNK1A1_ST	P16220	CREB1	P48729	CSNK1A1	S156	E152Q	152	Missense	distal	-4	no	22.985	22.608	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	20.411	Down-regulation
CK1_CK1_CK1-A_CSNK1A1_ST	Q9UKV8	AGO2	P48729	CSNK1A1	S831	S831P	831	Missense	central	0	yes	20.611	0.000	EPSD;PhosphoSitePlus	TCGA;COSMIC	20.411	Loss
CK1_CK1_CK1-A_CSNK1A1_ST	Q9UKV8	AGO2	P48729	CSNK1A1	S834	S831P	831	Missense	distal	-3	no	23.054	16.867	PhosphoSitePlus;EPSD	TCGA;COSMIC	20.411	Loss
CK1_CK1_CK1-A_CSNK1A1_ST	P11308	ERG	P48729	CSNK1A1	S46	M40I	40	Missense	distal	-6	no	29.392	28.523	EPSD;PhosphoSitePlus	TCGA;COSMIC	20.411	Down-regulation
CK1_CK1_CK1-A_CSNK1A1_ST	P25054	APC	P48729	CSNK1A1	S98	S92P	92	Missense	distal	-6	no	23.082	22.401	EPSD	TCGA;ICGC;COSMIC	20.411	Down-regulation
CK1_CK1_CK1-A_CSNK1A1_ST	P25054	APC	P48729	CSNK1A1	S107	G108A	108	Missense	proximal	1	no	22.831	22.575	EPSD	TCGA;ICGC;COSMIC	20.411	Down-regulation
CK1_CK1_CK1-A_CSNK1A1_ST	P25054	APC	P48729	CSNK1A1	S107	E109A	109	Missense	proximal	2	no	22.831	22.051	EPSD	TCGA;ICGC;COSMIC	20.411	Down-regulation
CK1_CK1_CK1-A_CSNK1A1_ST	P25054	APC	P48729	CSNK1A1	S130	N125S	125	Missense	distal	-5	no	23.805	23.976	EPSD	TCGA	20.411	Up-regulation
CK1_CK1_CK1-A_CSNK1A1_ST	P25054	APC	P48729	CSNK1A1	S130	E136K	136	Missense	distal	6	no	23.805	23.718	EPSD	TCGA;ICGC;COSMIC	20.411	Down-regulation
CK1_CK1_CK1-A_CSNK1A1_ST	P25054	APC	P48729	CSNK1A1	S293	S299C	299	Missense	distal	6	no	23.718	23.293	EPSD	TCGA;ICGC;COSMIC	20.411	Down-regulation
CK1_CK1_CK1-A_CSNK1A1_ST	P25054	APC	P48729	CSNK1A1	S293	S294F	294	Missense	proximal	1	no	23.718	23.661	EPSD	TCGA;ICGC;COSMIC	20.411	Down-regulation
CK1_CK1_CK1-A_CSNK1A1_ST	P25054	APC	P48729	CSNK1A1	S293	A289V	289	Missense	distal	-4	no	23.718	22.534	EPSD	TCGA;ICGC;COSMIC	20.411	Down-regulation
CK1_CK1_CK1-A_CSNK1A1_ST	P25054	APC	P48729	CSNK1A1	S780	N778S	778	Missense	proximal	-2	no	19.051	21.293	EPSD	TCGA;ICGC;COSMIC	20.411	Gain
CK1_CK1_CK1-A_CSNK1A1_ST	P25054	APC	P48729	CSNK1A1	S843	D842V	842	Missense	proximal	-1	no	21.386	20.227	EPSD	TCGA;ICGC;COSMIC	20.411	Loss
CK1_CK1_CK1-A_CSNK1A1_ST	P25054	APC	P48729	CSNK1A1	S846	D842V	842	Missense	distal	-4	no	27.884	24.106	EPSD	TCGA;ICGC;COSMIC	20.411	Down-regulation
CK1_CK1_CK1-A_CSNK1A1_ST	P25054	APC	P48729	CSNK1A1	S905	S905R	905	Missense	central	0	yes	23.470	0.000	EPSD	TCGA	20.411	Loss
CK1_CK1_CK1-A_CSNK1A1_ST	P25054	APC	P48729	CSNK1A1	S905	S906Y	906	Missense	proximal	1	no	23.470	23.401	EPSD	TCGA;ICGC;COSMIC	20.411	Down-regulation
CK1_CK1_CK1-A_CSNK1A1_ST	P25054	APC	P48729	CSNK1A1	S906	S905R	905	Missense	proximal	-1	no	21.922	21.456	EPSD	TCGA	20.411	Down-regulation
CK1_CK1_CK1-A_CSNK1A1_ST	P25054	APC	P48729	CSNK1A1	S906	S906Y	906	Missense	central	0	yes	21.922	0.000	EPSD	TCGA;ICGC;COSMIC	20.411	Loss
CK1_CK1_CK1-A_CSNK1A1_ST	P25054	APC	P48729	CSNK1A1	S908	S905R	905	Missense	distal	-3	no	21.006	16.780	EPSD	TCGA	20.411	Loss
CK1_CK1_CK1-A_CSNK1A1_ST	P25054	APC	P48729	CSNK1A1	S908	S906Y	906	Missense	proximal	-2	no	21.006	18.964	EPSD	TCGA;ICGC;COSMIC	20.411	Loss
CK1_CK1_CK1-A_CSNK1A1_ST	P25054	APC	P48729	CSNK1A1	S966	S959Y	959	Missense	distal	-7	no	21.829	20.361	EPSD	TCGA;ICGC;COSMIC	20.411	Loss
CK1_CK1_CK1-A_CSNK1A1_ST	P25054	APC	P48729	CSNK1A1	S966	S966G	966	Missense	central	0	yes	21.829	0.000	EPSD	TCGA;ICGC;COSMIC	20.411	Loss
CK1_CK1_CK1-A_CSNK1A1_ST	P25054	APC	P48729	CSNK1A1	S982	R976K	976	Missense	distal	-6	no	22.598	22.178	EPSD	TCGA;ICGC;COSMIC	20.411	Down-regulation
CK1_CK1_CK1-A_CSNK1A1_ST	P25054	APC	P48729	CSNK1A1	S982	P981S	981	Missense	proximal	-1	no	22.598	22.590	EPSD	TCGA;ICGC;COSMIC	20.411	Down-regulation
CK1_CK1_CK1-A_CSNK1A1_ST	P25054	APC	P48729	CSNK1A1	S982	S982L	982	Missense	central	0	yes	22.598	0.000	EPSD	TCGA;ICGC;COSMIC	20.411	Loss
CK1_CK1_CK1-A_CSNK1A1_ST	P25054	APC	P48729	CSNK1A1	S982	G977C	977	Missense	distal	-5	no	22.598	21.001	EPSD	TCGA;ICGC;COSMIC	20.411	Down-regulation
CK1_CK1_CK1-A_CSNK1A1_ST	P25054	APC	P48729	CSNK1A1	S985	P981S	981	Missense	distal	-4	no	20.558	23.250	EPSD	TCGA;ICGC;COSMIC	20.411	Up-regulation
CK1_CK1_CK1-A_CSNK1A1_ST	P25054	APC	P48729	CSNK1A1	S985	S982L	982	Missense	distal	-3	no	20.558	13.964	EPSD	TCGA;ICGC;COSMIC	20.411	Loss
CK1_CK1_CK1-A_CSNK1A1_ST	P25054	APC	P48729	CSNK1A1	S987	K993Q	993	Missense	distal	6	no	22.463	22.570	EPSD	TCGA;COSMIC	20.411	Up-regulation
CK1_CK1_CK1-A_CSNK1A1_ST	P25054	APC	P48729	CSNK1A1	S987	P981S	981	Missense	distal	-6	no	22.463	23.144	EPSD	TCGA;ICGC;COSMIC	20.411	Up-regulation
CK1_CK1_CK1-A_CSNK1A1_ST	P25054	APC	P48729	CSNK1A1	S987	S982L	982	Missense	distal	-5	no	22.463	21.834	EPSD	TCGA;ICGC;COSMIC	20.411	Down-regulation
CK1_CK1_CK1-A_CSNK1A1_ST	P25054	APC	P48729	CSNK1A1	S992	K993Q	993	Missense	proximal	1	no	22.129	22.573	EPSD	TCGA;COSMIC	20.411	Up-regulation
CK1_CK1_CK1-A_CSNK1A1_ST	P25054	APC	P48729	CSNK1A1	S1081	V1077D	1077	Missense	distal	-4	no	17.188	20.967	EPSD	TCGA;ICGC;COSMIC	20.411	Gain
CK1_CK1_CK1-A_CSNK1A1_ST	P25054	APC	P48729	CSNK1A1	S1148	E1149K	1149	Missense	proximal	1	no	22.107	21.647	EPSD	TCGA;ICGC;COSMIC	20.411	Down-regulation
CK1_CK1_CK1-A_CSNK1A1_ST	P25054	APC	P48729	CSNK1A1	S1148	T1141I	1141	Missense	distal	-7	no	22.107	22.895	EPSD	TCGA;ICGC;COSMIC	20.411	Up-regulation
CK1_CK1_CK1-A_CSNK1A1_ST	P25054	APC	P48729	CSNK1A1	S1238	S1234G	1234	Missense	distal	-4	no	23.779	23.944	EPSD	TCGA;ICGC;COSMIC	20.411	Up-regulation
CK1_CK1_CK1-A_CSNK1A1_ST	P25054	APC	P48729	CSNK1A1	S1279	S1278L	1278	Missense	proximal	-1	no	22.356	22.081	EPSD	TCGA;ICGC;COSMIC	20.411	Down-regulation
CK1_CK1_CK1-A_CSNK1A1_ST	P25054	APC	P48729	CSNK1A1	S1279	S1272L	1272	Missense	distal	-7	no	22.356	21.676	EPSD	TCGA;ICGC;COSMIC	20.411	Down-regulation
CK1_CK1_CK1-A_CSNK1A1_ST	P25054	APC	P48729	CSNK1A1	S1279	L1277V	1277	Missense	proximal	-2	no	22.356	22.854	EPSD	TCGA	20.411	Up-regulation
CK1_CK1_CK1-A_CSNK1A1_ST	P25054	APC	P48729	CSNK1A1	S1343	S1343C	1343	Missense	central	0	yes	20.865	0.000	EPSD	TCGA;ICGC;COSMIC	20.411	Loss
CK1_CK1_CK1-A_CSNK1A1_ST	P25054	APC	P48729	CSNK1A1	S1392	R1386K	1386	Missense	distal	-6	no	21.764	21.343	EPSD	TCGA;ICGC;COSMIC	20.411	Down-regulation
CK1_CK1_CK1-A_CSNK1A1_ST	P25054	APC	P48729	CSNK1A1	S1392	S1389F	1389	Missense	distal	-3	no	21.764	16.111	EPSD	TCGA;ICGC;COSMIC	20.411	Loss
CK1_CK1_CK1-A_CSNK1A1_ST	P25054	APC	P48729	CSNK1A1	S1392	L1393I	1393	Missense	proximal	1	no	21.764	21.674	EPSD	TCGA;ICGC;COSMIC	20.411	Down-regulation
CK1_CK1_CK1-A_CSNK1A1_ST	P25054	APC	P48729	CSNK1A1	S1392	R1399H	1399	Missense	distal	7	no	21.764	21.890	EPSD	TCGA;ICGC;COSMIC	20.411	Up-regulation
CK1_CK1_CK1-A_CSNK1A1_ST	P25054	APC	P48729	CSNK1A1	S1395	S1389F	1389	Missense	distal	-6	no	21.416	20.203	EPSD	TCGA;ICGC;COSMIC	20.411	Loss
CK1_CK1_CK1-A_CSNK1A1_ST	P25054	APC	P48729	CSNK1A1	S1395	L1393I	1393	Missense	proximal	-2	no	21.416	22.091	EPSD	TCGA;ICGC;COSMIC	20.411	Up-regulation
CK1_CK1_CK1-A_CSNK1A1_ST	P25054	APC	P48729	CSNK1A1	S1395	R1399H	1399	Missense	distal	4	no	21.416	21.285	EPSD	TCGA;ICGC;COSMIC	20.411	Down-regulation
CK1_CK1_CK1-A_CSNK1A1_ST	P25054	APC	P48729	CSNK1A1	S1395	S1400L	1400	Missense	distal	5	no	21.416	21.728	EPSD	TCGA;ICGC;COSMIC;CCLE	20.411	Up-regulation
CK1_CK1_CK1-A_CSNK1A1_ST	P25054	APC	P48729	CSNK1A1	S1398	S1404F	1404	Missense	distal	6	no	25.131	24.554	EPSD	TCGA;ICGC;COSMIC	20.411	Down-regulation
CK1_CK1_CK1-A_CSNK1A1_ST	P25054	APC	P48729	CSNK1A1	S1398	L1393I	1393	Missense	distal	-5	no	25.131	25.588	EPSD	TCGA;ICGC;COSMIC	20.411	Up-regulation
CK1_CK1_CK1-A_CSNK1A1_ST	P25054	APC	P48729	CSNK1A1	S1398	R1399H	1399	Missense	proximal	1	no	25.131	25.045	EPSD	TCGA;ICGC;COSMIC	20.411	Down-regulation
CK1_CK1_CK1-A_CSNK1A1_ST	P25054	APC	P48729	CSNK1A1	S1398	S1400L	1400	Missense	proximal	2	no	25.131	24.146	EPSD	TCGA;ICGC;COSMIC;CCLE	20.411	Down-regulation
CK1_CK1_CK1-A_CSNK1A1_ST	P25054	APC	P48729	CSNK1A1	S1501	E1494Q	1494	Missense	distal	-7	no	26.380	25.923	EPSD	TCGA;ICGC;COSMIC	20.411	Down-regulation
CK1_CK1_CK1-A_CSNK1A1_ST	P25054	APC	P48729	CSNK1A1	S1501	A1508D	1508	Missense	distal	7	no	26.380	26.263	EPSD	TCGA;ICGC	20.411	Down-regulation
CK1_CK1_CK1-A_CSNK1A1_ST	P25054	APC	P48729	CSNK1A1	S1504	A1508D	1508	Missense	distal	4	no	24.414	24.472	EPSD;PhosphoSitePlus	TCGA;ICGC	20.411	Up-regulation
CK1_CK1_CK1-A_CSNK1A1_ST	P25054	APC	P48729	CSNK1A1	S1505	A1508D	1508	Missense	distal	3	no	20.965	23.916	EPSD;PhosphoSitePlus	TCGA;ICGC	20.411	Up-regulation
CK1_CK1_CK1-A_CSNK1A1_ST	P25054	APC	P48729	CSNK1A1	S1507	A1508D	1508	Missense	proximal	1	no	26.279	26.489	PhosphoSitePlus;EPSD	TCGA;ICGC	20.411	Up-regulation
CK1_CK1_CK1-A_CSNK1A1_ST	P25054	APC	P48729	CSNK1A1	S1510	A1508D	1508	Missense	proximal	-2	no	23.496	24.338	EPSD;PhosphoSitePlus	TCGA;ICGC	20.411	Up-regulation
CK1_CK1_CK1-A_CSNK1A1_ST	P25054	APC	P48729	CSNK1A1	S1656	D1659V	1659	Missense	distal	3	no	20.731	17.424	EPSD	TCGA;ICGC;COSMIC	20.411	Loss
CK1_CK1_CK1-A_CSNK1A1_ST	P25054	APC	P48729	CSNK1A1	S2034	D2033G	2033	Missense	proximal	-1	no	22.264	22.536	EPSD	TCGA;ICGC;COSMIC	20.411	Up-regulation
CK1_CK1_CK1-A_CSNK1A1_ST	P25054	APC	P48729	CSNK1A1	S2034	S2029Y	2029	Missense	distal	-5	no	22.264	20.317	EPSD	TCGA;ICGC;COSMIC	20.411	Loss
CK1_CK1_CK1-A_CSNK1A1_ST	P25054	APC	P48729	CSNK1A1	S2034	S2029F	2029	Missense	distal	-5	no	22.264	20.363	EPSD	TCGA;ICGC;COSMIC	20.411	Loss
CK1_CK1_CK1-A_CSNK1A1_ST	P25054	APC	P48729	CSNK1A1	S2110	G2107S	2107	Missense	distal	-3	no	19.905	21.597	EPSD	TCGA;ICGC;COSMIC	20.411	Gain
CK1_CK1_CK1-A_CSNK1A1_ST	P25054	APC	P48729	CSNK1A1	S2307	S2307L	2307	Missense	central	0	yes	23.911	0.000	EPSD	TCGA;ICGC;COSMIC;CCLE	20.411	Loss
CK1_CK1_CK1-A_CSNK1A1_ST	P25054	APC	P48729	CSNK1A1	S2307	S2300C	2300	Missense	distal	-7	no	23.911	23.255	EPSD	TCGA;ICGC;COSMIC	20.411	Down-regulation
CK1_CK1_CK1-A_CSNK1A1_ST	P25054	APC	P48729	CSNK1A1	S2307	A2313S	2313	Missense	distal	6	no	23.911	24.269	EPSD	TCGA;ICGC;COSMIC	20.411	Up-regulation
CK1_CK1_CK1-A_CSNK1A1_ST	P25054	APC	P48729	CSNK1A1	S2307	S2300Y	2300	Missense	distal	-7	no	23.911	22.442	EPSD	TCGA	20.411	Down-regulation
CK1_CK1_CK1-A_CSNK1A1_ST	P25054	APC	P48729	CSNK1A1	S2310	S2307L	2307	Missense	distal	-3	no	22.245	15.652	EPSD	TCGA;ICGC;COSMIC;CCLE	20.411	Loss
CK1_CK1_CK1-A_CSNK1A1_ST	P25054	APC	P48729	CSNK1A1	S2310	A2313S	2313	Missense	distal	3	no	22.245	24.475	EPSD	TCGA;ICGC;COSMIC	20.411	Up-regulation
CK1_CK1_CK1-A_CSNK1A1_ST	P25054	APC	P48729	CSNK1A1	S2424	S2429F	2429	Missense	distal	5	no	22.868	23.375	EPSD	TCGA;COSMIC	20.411	Up-regulation
CK1_CK1_CK1-A_CSNK1A1_ST	P25054	APC	P48729	CSNK1A1	S2424	D2430H	2430	Missense	distal	6	no	22.868	22.674	EPSD	TCGA;ICGC;COSMIC	20.411	Down-regulation
CK1_CK1_CK1-A_CSNK1A1_ST	P25054	APC	P48729	CSNK1A1	S2425	S2429F	2429	Missense	distal	4	no	20.707	20.620	EPSD	TCGA;COSMIC	20.411	Down-regulation
CK1_CK1_CK1-A_CSNK1A1_ST	P25054	APC	P48729	CSNK1A1	S2425	D2430H	2430	Missense	distal	5	no	20.707	21.005	EPSD	TCGA;ICGC;COSMIC	20.411	Up-regulation
CK1_CK1_CK1-A_CSNK1A1_ST	P25054	APC	P48729	CSNK1A1	S2427	S2429F	2429	Missense	proximal	2	no	22.212	21.189	EPSD	TCGA;COSMIC	20.411	Down-regulation
CK1_CK1_CK1-A_CSNK1A1_ST	P25054	APC	P48729	CSNK1A1	S2427	D2430H	2430	Missense	distal	3	no	22.212	17.664	EPSD	TCGA;ICGC;COSMIC	20.411	Loss
CK1_CK1_CK1-A_CSNK1A1_ST	P25054	APC	P48729	CSNK1A1	S2429	S2429F	2429	Missense	central	0	yes	21.026	0.000	EPSD	TCGA;COSMIC	20.411	Loss
CK1_CK1_CK1-A_CSNK1A1_ST	P25054	APC	P48729	CSNK1A1	S2429	D2430H	2430	Missense	proximal	1	no	21.026	20.712	EPSD	TCGA;ICGC;COSMIC	20.411	Down-regulation
CK1_CK1_CK1-A_CSNK1A1_ST	P25054	APC	P48729	CSNK1A1	S2461	S2464Y	2464	Missense	distal	3	no	20.924	18.119	EPSD	TCGA;ICGC;COSMIC	20.411	Loss
CK1_CK1_CK1-A_CSNK1A1_ST	P25054	APC	P48729	CSNK1A1	S2466	A2472D	2472	Missense	distal	6	no	21.188	21.475	EPSD	TCGA;ICGC	20.411	Up-regulation
CK1_CK1_CK1-A_CSNK1A1_ST	P25054	APC	P48729	CSNK1A1	S2466	S2464Y	2464	Missense	proximal	-2	no	21.188	19.146	EPSD	TCGA;ICGC;COSMIC	20.411	Loss
CK1_CK1_CK1-A_CSNK1A1_ST	P25054	APC	P48729	CSNK1A1	S2531	R2525C	2525	Missense	distal	-6	no	22.353	22.027	EPSD	TCGA;ICGC;COSMIC	20.411	Down-regulation
CK1_CK1_CK1-A_CSNK1A1_ST	P25054	APC	P48729	CSNK1A1	S2531	H2532Y	2532	Missense	proximal	1	no	22.353	22.423	EPSD	TCGA;ICGC;COSMIC	20.411	Up-regulation
CK1_CK1_CK1-A_CSNK1A1_ST	P25054	APC	P48729	CSNK1A1	S2537	P2540S	2540	Missense	distal	3	no	18.315	22.580	EPSD	TCGA;ICGC;COSMIC	20.411	Gain
CK1_CK1_CK1-A_CSNK1A1_ST	P25054	APC	P48729	CSNK1A1	S2572	S2569N	2569	Missense	distal	-3	no	22.288	17.379	EPSD	TCGA;ICGC;COSMIC	20.411	Loss
CK1_CK1_CK1-A_CSNK1A1_ST	P25054	APC	P48729	CSNK1A1	S2572	L2574I	2574	Missense	proximal	2	no	22.288	22.475	EPSD	TCGA;ICGC;COSMIC	20.411	Up-regulation
CK1_CK1_CK1-A_CSNK1A1_ST	P25054	APC	P48729	CSNK1A1	S2572	S2577P	2577	Missense	distal	5	no	22.288	22.536	EPSD	TCGA;ICGC	20.411	Up-regulation
CK1_CK1_CK1-A_CSNK1A1_ST	P25054	APC	P48729	CSNK1A1	S2575	S2569N	2569	Missense	distal	-6	no	24.897	23.883	EPSD	TCGA;ICGC;COSMIC	20.411	Down-regulation
CK1_CK1_CK1-A_CSNK1A1_ST	P25054	APC	P48729	CSNK1A1	S2575	L2574I	2574	Missense	proximal	-1	no	24.897	25.929	EPSD	TCGA;ICGC;COSMIC	20.411	Up-regulation
CK1_CK1_CK1-A_CSNK1A1_ST	P25054	APC	P48729	CSNK1A1	S2575	S2577P	2577	Missense	proximal	2	no	24.897	23.882	EPSD	TCGA;ICGC	20.411	Down-regulation
CK1_CK1_CK1-A_CSNK1A1_ST	P25054	APC	P48729	CSNK1A1	S2578	L2574I	2574	Missense	distal	-4	no	19.396	21.004	EPSD	TCGA;ICGC;COSMIC	20.411	Gain
CK1_CK1_CK1-A_CSNK1A1_ST	P25054	APC	P48729	CSNK1A1	S2580	K2585I	2585	Missense	distal	5	no	21.313	20.946	EPSD	TCGA;ICGC;COSMIC	20.411	Down-regulation
CK1_CK1_CK1-A_CSNK1A1_ST	P25054	APC	P48729	CSNK1A1	S2580	L2574I	2574	Missense	distal	-6	no	21.313	21.200	EPSD	TCGA;ICGC;COSMIC	20.411	Down-regulation
CK1_CK1_CK1-A_CSNK1A1_ST	P25054	APC	P48729	CSNK1A1	S2580	S2577P	2577	Missense	distal	-3	no	21.313	15.126	EPSD	TCGA;ICGC	20.411	Loss
CK1_CK1_CK1-A_CSNK1A1_ST	P25054	APC	P48729	CSNK1A1	S2674	S2671Y	2671	Missense	distal	-3	no	20.899	14.923	EPSD	TCGA;ICGC	20.411	Loss
CK1_CK1_CK1-A_CSNK1A1_ST	P25054	APC	P48729	CSNK1A1	S2674	S2674Y	2674	Missense	central	0	yes	20.899	0.000	EPSD	TCGA;ICGC;COSMIC	20.411	Loss
CK1_CK1_CK1-A_CSNK1A1_ST	P25054	APC	P48729	CSNK1A1	S2768	G2775V	2775	Missense	distal	7	no	20.854	21.031	EPSD	TCGA;ICGC;COSMIC	20.411	Up-regulation
CK1_CK1_CK1-A_CSNK1A1_ST	P25054	APC	P48729	CSNK1A1	S2771	G2775V	2775	Missense	distal	4	no	22.693	22.569	EPSD	TCGA;ICGC;COSMIC	20.411	Down-regulation
CK1_CK1_CK1-A_CSNK1A1_ST	P08238	HSP90AB1	P48729	CSNK1A1	S159	S164A	164	Missense	distal	5	no	22.549	22.867	EPSD	TCGA;ICGC;COSMIC	20.411	Up-regulation
CK1_CK1_CK1-A_CSNK1A1_ST	P08238	HSP90AB1	P48729	CSNK1A1	S160	S164A	164	Missense	distal	4	no	27.772	27.748	EPSD	TCGA;ICGC;COSMIC	20.411	Down-regulation
CK1_CK1_CK1-A_CSNK1A1_ST	P08238	HSP90AB1	P48729	CSNK1A1	T166	S164A	164	Missense	proximal	-2	no	20.706	19.747	EPSD	TCGA;ICGC;COSMIC	20.411	Loss
CK1_CK1_CK1-A_CSNK1A1_ST	P08238	HSP90AB1	P48729	CSNK1A1	T166	H171Y	171	Missense	distal	5	no	20.706	20.660	EPSD	TCGA;ICGC;COSMIC	20.411	Down-regulation
CK1_CK1_CK1-A_CSNK1A1_ST	P08238	HSP90AB1	P48729	CSNK1A1	S226	D228N	228	Missense	proximal	2	no	20.638	19.445	EPSD	TCGA;ICGC;COSMIC	20.411	Loss
CK1_CK1_CK1-A_CSNK1A1_ST	P08238	HSP90AB1	P48729	CSNK1A1	S226	I225V	225	Missense	proximal	-1	no	20.638	19.147	EPSD	TCGA;ICGC;COSMIC;GDSC;CCLE	20.411	Loss
CK1_CK1_CK1-A_CSNK1A1_ST	P08238	HSP90AB1	P48729	CSNK1A1	S226	E222D	222	Missense	distal	-4	no	20.638	21.074	EPSD	TCGA;ICGC	20.411	Up-regulation
CK1_CK1_CK1-A_CSNK1A1_ST	P08238	HSP90AB1	P48729	CSNK1A1	S255	E251K	251	Missense	distal	-4	no	23.176	19.479	EPSD	TCGA;ICGC;COSMIC;GDSC;CCLE	20.411	Loss
CK1_CK1_CK1-A_CSNK1A1_ST	P08238	HSP90AB1	P48729	CSNK1A1	S255	I250V	250	Missense	distal	-5	no	23.176	21.589	EPSD	TCGA;ICGC;COSMIC	20.411	Down-regulation
CK1_CK1_CK1-A_CSNK1A1_ST	P08238	HSP90AB1	P48729	CSNK1A1	S255	D256V	256	Missense	proximal	1	no	23.176	22.988	EPSD	TCGA;ICGC;COSMIC	20.411	Down-regulation
CK1_CK1_CK1-A_CSNK1A1_ST	P08238	HSP90AB1	P48729	CSNK1A1	S255	D256A	256	Missense	proximal	1	no	23.176	22.966	EPSD	TCGA;ICGC;COSMIC	20.411	Down-regulation
CK1_CK1_CK1-A_CSNK1A1_ST	P08238	HSP90AB1	P48729	CSNK1A1	S261	K263E	263	Missense	proximal	2	no	22.901	23.877	EPSD	TCGA;ICGC;COSMIC	20.411	Up-regulation
CK1_CK1_CK1-A_CSNK1A1_ST	P08238	HSP90AB1	P48729	CSNK1A1	S261	D256V	256	Missense	distal	-5	no	22.901	21.063	EPSD	TCGA;ICGC;COSMIC	20.411	Down-regulation
CK1_CK1_CK1-A_CSNK1A1_ST	P08238	HSP90AB1	P48729	CSNK1A1	S261	D256A	256	Missense	distal	-5	no	22.901	21.511	EPSD	TCGA;ICGC;COSMIC	20.411	Down-regulation
CK1_CK1_CK1-A_CSNK1A1_ST	P08238	HSP90AB1	P48729	CSNK1A1	S261	K265N	265	Missense	distal	4	no	22.901	22.906	EPSD	TCGA;ICGC;COSMIC	20.411	Up-regulation
CK1_CK1_CK1-A_CSNK1A1_ST	P08238	HSP90AB1	P48729	CSNK1A1	S261	K267N	267	Missense	distal	6	no	22.901	23.068	EPSD	TCGA;ICGC;COSMIC	20.411	Up-regulation
CK1_CK1_CK1-A_CSNK1A1_ST	P08238	HSP90AB1	P48729	CSNK1A1	T297	E303K	303	Missense	distal	6	no	20.976	20.889	EPSD	TCGA;ICGC;COSMIC	20.411	Down-regulation
CK1_CK1_CK1-A_CSNK1A1_ST	P08238	HSP90AB1	P48729	CSNK1A1	T297	F304L	304	Missense	distal	7	no	20.976	20.824	EPSD	TCGA;ICGC;COSMIC	20.411	Down-regulation
CK1_CK1_CK1-A_CSNK1A1_ST	P08238	HSP90AB1	P48729	CSNK1A1	S669	S665C	665	Missense	distal	-4	no	25.613	22.913	EPSD	TCGA;ICGC;COSMIC	20.411	Down-regulation
CK1_CK1_CK1-A_CSNK1A1_ST	P08238	HSP90AB1	P48729	CSNK1A1	S669	H676Y	676	Missense	distal	7	no	25.613	25.633	EPSD	TCGA;ICGC;COSMIC	20.411	Up-regulation
CK1_CK1_CK1-A_CSNK1A1_ST	P08238	HSP90AB1	P48729	CSNK1A1	S669	A662T	662	Missense	distal	-7	no	25.613	24.641	EPSD	TCGA;ICGC;COSMIC;CCLE	20.411	Down-regulation
CK1_CK1_CK1-A_CSNK1A1_ST	O75581	LRP6	P48729	CSNK1A1	S171	R165C	165	Missense	distal	-6	no	21.268	20.943	EPSD	TCGA;ICGC;COSMIC;GDSC;CCLE	20.411	Down-regulation
CK1_CK1_CK1-A_CSNK1A1_ST	O75581	LRP6	P48729	CSNK1A1	S171	N178S	178	Missense	distal	7	no	21.268	21.222	EPSD	TCGA;ICGC	20.411	Down-regulation
CK1_CK1_CK1-A_CSNK1A1_ST	O75581	LRP6	P48729	CSNK1A1	S172	R165C	165	Missense	distal	-7	no	25.826	24.768	EPSD	TCGA;ICGC;COSMIC;GDSC;CCLE	20.411	Down-regulation
CK1_CK1_CK1-A_CSNK1A1_ST	O75581	LRP6	P48729	CSNK1A1	S172	N178S	178	Missense	distal	6	no	25.826	26.043	EPSD	TCGA;ICGC	20.411	Up-regulation
CK1_CK1_CK1-A_CSNK1A1_ST	O75581	LRP6	P48729	CSNK1A1	S1025	R1026C	1026	Missense	proximal	1	no	20.899	20.748	EPSD	TCGA;ICGC;COSMIC	20.411	Down-regulation
CK1_CK1_CK1-A_CSNK1A1_ST	O75581	LRP6	P48729	CSNK1A1	S1025	R1026H	1026	Missense	proximal	1	no	20.899	20.812	EPSD	TCGA;ICGC;COSMIC	20.411	Down-regulation
CK1_CK1_CK1-A_CSNK1A1_ST	O75581	LRP6	P48729	CSNK1A1	T1408	E1407K	1407	Missense	proximal	-1	no	23.662	22.021	EPSD	TCGA;COSMIC	20.411	Down-regulation
CK1_CK1_CK1-A_CSNK1A1_ST	O75581	LRP6	P48729	CSNK1A1	S1444	S1447C	1447	Missense	distal	3	no	22.395	18.352	EPSD	TCGA;COSMIC	20.411	Loss
CK1_CK1_CK1-A_CSNK1A1_ST	O75581	LRP6	P48729	CSNK1A1	S1444	R1441Q	1441	Missense	distal	-3	no	22.395	23.350	EPSD	TCGA;COSMIC	20.411	Up-regulation
CK1_CK1_CK1-A_CSNK1A1_ST	O75581	LRP6	P48729	CSNK1A1	S1444	M1445I	1445	Missense	proximal	1	no	22.395	22.626	EPSD	TCGA;COSMIC	20.411	Up-regulation
CK1_CK1_CK1-A_CSNK1A1_ST	O75581	LRP6	P48729	CSNK1A1	S1544	Y1541S	1541	Missense	distal	-3	no	17.126	23.101	EPSD	TCGA;COSMIC	20.411	Gain
CK1_CK1_CK1-A_CSNK1A1_ST	Q12778	FOXO1	P48729	CSNK1A1	S164	N162K	162	Missense	proximal	-2	no	21.680	22.607	EPSD	TCGA;ICGC;COSMIC	20.411	Up-regulation
CK1_CK1_CK1-A_CSNK1A1_ST	Q12778	FOXO1	P48729	CSNK1A1	S205	W209C	209	Missense	distal	4	no	30.590	30.717	EPSD	TCGA;ICGC;COSMIC	20.411	Up-regulation
CK1_CK1_CK1-A_CSNK1A1_ST	Q12778	FOXO1	P48729	CSNK1A1	S206	W209C	209	Missense	distal	3	no	20.936	18.548	EPSD	TCGA;ICGC;COSMIC	20.411	Loss
CK1_CK1_CK1-A_CSNK1A1_ST	Q12778	FOXO1	P48729	CSNK1A1	S212	W209C	209	Missense	distal	-3	no	24.169	20.793	EPSD	TCGA;ICGC;COSMIC	20.411	Down-regulation
CK1_CK1_CK1-A_CSNK1A1_ST	Q12778	FOXO1	P48729	CSNK1A1	S212	R214H	214	Missense	proximal	2	no	24.169	23.443	EPSD	TCGA;ICGC;COSMIC	20.411	Down-regulation
CK1_CK1_CK1-A_CSNK1A1_ST	Q12778	FOXO1	P48729	CSNK1A1	S212	R214C	214	Missense	proximal	2	no	24.169	23.791	EPSD	TCGA;ICGC;COSMIC	20.411	Down-regulation
CK1_CK1_CK1-A_CSNK1A1_ST	Q12778	FOXO1	P48729	CSNK1A1	S261	A255T	255	Missense	distal	-6	no	19.982	20.509	EPSD	TCGA;ICGC;COSMIC	20.411	Gain
CK1_CK1_CK1-A_CSNK1A1_ST	Q12778	FOXO1	P48729	CSNK1A1	S287	G289E	289	Missense	proximal	2	no	21.575	21.180	EPSD	TCGA;ICGC;COSMIC	20.411	Down-regulation
CK1_CK1_CK1-A_CSNK1A1_ST	Q12778	FOXO1	P48729	CSNK1A1	S303	W310L	310	Missense	distal	7	no	21.233	20.785	EPSD	TCGA;ICGC;COSMIC	20.411	Down-regulation
CK1_CK1_CK1-A_CSNK1A1_ST	Q12778	FOXO1	P48729	CSNK1A1	S303	P299S	299	Missense	distal	-4	no	21.233	23.925	EPSD	TCGA;ICGC;COSMIC	20.411	Up-regulation
CK1_CK1_CK1-A_CSNK1A1_ST	Q12778	FOXO1	P48729	CSNK1A1	S311	W310L	310	Missense	proximal	-1	no	19.506	20.734	EPSD	TCGA;ICGC;COSMIC	20.411	Gain
CK1_CK1_CK1-A_CSNK1A1_ST	Q12778	FOXO1	P48729	CSNK1A1	S322	G326R	326	Missense	distal	4	no	25.541	25.540	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	20.411	Down-regulation
CK1_CK1_CK1-A_CSNK1A1_ST	Q12778	FOXO1	P48729	CSNK1A1	S322	S329L	329	Missense	distal	7	no	25.541	25.576	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	20.411	Up-regulation
CK1_CK1_CK1-A_CSNK1A1_ST	Q12778	FOXO1	P48729	CSNK1A1	S322	T323A	323	Missense	proximal	1	no	25.541	25.496	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	20.411	Down-regulation
CK1_CK1_CK1-A_CSNK1A1_ST	Q12778	FOXO1	P48729	CSNK1A1	S322	R316Q	316	Missense	distal	-6	no	25.541	25.729	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	20.411	Up-regulation
CK1_CK1_CK1-A_CSNK1A1_ST	Q12778	FOXO1	P48729	CSNK1A1	S325	M332I	332	Missense	distal	7	no	21.238	21.092	PhosphoSitePlus;EPSD	TCGA;COSMIC	20.411	Down-regulation
CK1_CK1_CK1-A_CSNK1A1_ST	Q12778	FOXO1	P48729	CSNK1A1	S325	G326R	326	Missense	proximal	1	no	21.238	20.964	PhosphoSitePlus;EPSD	TCGA;ICGC;COSMIC	20.411	Down-regulation
CK1_CK1_CK1-A_CSNK1A1_ST	Q12778	FOXO1	P48729	CSNK1A1	S325	S329L	329	Missense	distal	4	no	21.238	21.268	PhosphoSitePlus;EPSD	TCGA;ICGC;COSMIC	20.411	Up-regulation
CK1_CK1_CK1-A_CSNK1A1_ST	Q12778	FOXO1	P48729	CSNK1A1	S325	T323A	323	Missense	proximal	-2	no	21.238	21.411	PhosphoSitePlus;EPSD	TCGA;ICGC;COSMIC	20.411	Up-regulation
CK1_CK1_CK1-A_CSNK1A1_ST	Q12778	FOXO1	P48729	CSNK1A1	S509	K515N	515	Missense	distal	6	no	20.770	20.937	EPSD	TCGA;ICGC;COSMIC	20.411	Up-regulation
CK1_CK1_CK1-A_CSNK1A1_ST	Q12778	FOXO1	P48729	CSNK1A1	S509	S502L	502	Missense	distal	-7	no	20.770	20.090	EPSD	TCGA;ICGC;COSMIC	20.411	Loss
CK1_CK1_CK1-A_CSNK1A1_ST	P40337	VHL	P48729	CSNK1A1	S33	E26G	26	Missense	distal	-7	no	25.228	25.735	EPSD	TCGA;ICGC;COSMIC	20.411	Up-regulation
CK1_CK1_CK1-A_CSNK1A1_ST	P40337	VHL	P48729	CSNK1A1	S72	S65W	65	Missense	distal	-7	no	21.150	19.516	PhosphoSitePlus	TCGA;ICGC;COSMIC;CCLE	20.411	Loss
CK1_CK1_CK1-A_CSNK1A1_ST	P40337	VHL	P48729	CSNK1A1	S72	V74D	74	Missense	proximal	2	no	21.150	22.565	PhosphoSitePlus	TCGA;ICGC;COSMIC	20.411	Up-regulation
CK1_CK1_CK1-A_CSNK1A1_ST	P40337	VHL	P48729	CSNK1A1	S72	N78D	78	Missense	distal	6	no	21.150	21.297	PhosphoSitePlus	TCGA;ICGC;COSMIC	20.411	Up-regulation
CK1_CK1_CK1-A_CSNK1A1_ST	P40337	VHL	P48729	CSNK1A1	S72	N78Y	78	Missense	distal	6	no	21.150	20.791	PhosphoSitePlus	TCGA;ICGC;COSMIC	20.411	Down-regulation
CK1_CK1_CK1-A_CSNK1A1_ST	P40337	VHL	P48729	CSNK1A1	S72	R79G	79	Missense	distal	7	no	21.150	21.065	PhosphoSitePlus	TCGA;ICGC;COSMIC	20.411	Down-regulation
CK1_CK1_CK1-A_CSNK1A1_ST	Q13158	FADD	P48729	CSNK1A1	S16	E19K	19	Missense	distal	3	no	23.399	19.268	EPSD	TCGA;ICGC;COSMIC	20.411	Loss
CK1_CK1_CK1-A_CSNK1A1_ST	Q13158	FADD	P48729	CSNK1A1	S16	H9R	9	Missense	distal	-7	no	23.399	24.884	EPSD	TCGA;ICGC;COSMIC	20.411	Up-regulation
CK1_CK1_CK1-A_CSNK1A1_ST	Q13158	FADD	P48729	CSNK1A1	S16	S12W	12	Missense	distal	-4	no	23.399	22.597	EPSD	TCGA;ICGC;COSMIC	20.411	Down-regulation
CK1_CK1_CK1-A_CSNK1A1_ST	Q13501	SQSTM1	P48729	CSNK1A1	S152	S152C	152	Missense	central	0	yes	20.756	0.000	EPSD	TCGA;ICGC;COSMIC	20.411	Loss
CK1_CK1_CK1-A_CSNK1A1_ST	Q13501	SQSTM1	P48729	CSNK1A1	S176	G173R	173	Missense	distal	-3	no	20.545	18.011	EPSD	TCGA;ICGC;COSMIC	20.411	Loss
CK1_CK1_CK1-A_CSNK1A1_ST	Q13501	SQSTM1	P48729	CSNK1A1	S176	R183H	183	Missense	distal	7	no	20.545	20.671	EPSD	TCGA;ICGC	20.411	Up-regulation
CK1_CK1_CK1-A_CSNK1A1_ST	Q13501	SQSTM1	P48729	CSNK1A1	S180	G173R	173	Missense	distal	-7	no	26.136	25.485	EPSD	TCGA;ICGC;COSMIC	20.411	Down-regulation
CK1_CK1_CK1-A_CSNK1A1_ST	Q13501	SQSTM1	P48729	CSNK1A1	S180	R183H	183	Missense	distal	3	no	26.136	24.753	EPSD	TCGA;ICGC	20.411	Down-regulation
CK1_CK1_CK1-A_CSNK1A1_ST	Q13501	SQSTM1	P48729	CSNK1A1	S180	L185F	185	Missense	distal	5	no	26.136	26.331	EPSD	TCGA	20.411	Up-regulation
CK1_CK1_CK1-A_CSNK1A1_ST	Q13501	SQSTM1	P48729	CSNK1A1	S182	R183H	183	Missense	proximal	1	no	21.169	21.083	EPSD	TCGA;ICGC	20.411	Down-regulation
CK1_CK1_CK1-A_CSNK1A1_ST	Q13501	SQSTM1	P48729	CSNK1A1	S182	L185F	185	Missense	distal	3	no	21.169	22.461	EPSD	TCGA	20.411	Up-regulation
CK1_CK1_CK1-A_CSNK1A1_ST	Q13501	SQSTM1	P48729	CSNK1A1	S224	S229L	229	Missense	distal	5	no	23.092	23.404	EPSD	TCGA;COSMIC	20.411	Up-regulation
CK1_CK1_CK1-A_CSNK1A1_ST	Q13501	SQSTM1	P48729	CSNK1A1	S224	P228L	228	Missense	distal	4	no	23.092	23.158	EPSD	TCGA;COSMIC	20.411	Up-regulation
CK1_CK1_CK1-A_CSNK1A1_ST	Q13501	SQSTM1	P48729	CSNK1A1	S226	S229L	229	Missense	distal	3	no	26.569	22.817	EPSD	TCGA;COSMIC	20.411	Down-regulation
CK1_CK1_CK1-A_CSNK1A1_ST	Q13501	SQSTM1	P48729	CSNK1A1	S226	P228L	228	Missense	proximal	2	no	26.569	26.599	EPSD	TCGA;COSMIC	20.411	Up-regulation
CK1_CK1_CK1-A_CSNK1A1_ST	Q13501	SQSTM1	P48729	CSNK1A1	S229	S229L	229	Missense	central	0	yes	20.534	0.000	EPSD	TCGA;COSMIC	20.411	Loss
CK1_CK1_CK1-A_CSNK1A1_ST	Q13501	SQSTM1	P48729	CSNK1A1	S229	P228L	228	Missense	proximal	-1	no	20.534	20.250	EPSD	TCGA;COSMIC	20.411	Loss
CK1_CK1_CK1-A_CSNK1A1_ST	Q13501	SQSTM1	P48729	CSNK1A1	S233	S229L	229	Missense	distal	-4	no	24.084	20.277	EPSD	TCGA;COSMIC	20.411	Loss
CK1_CK1_CK1-A_CSNK1A1_ST	Q13501	SQSTM1	P48729	CSNK1A1	S233	K238N	238	Missense	distal	5	no	24.084	24.093	EPSD	TCGA;ICGC;COSMIC	20.411	Up-regulation
CK1_CK1_CK1-A_CSNK1A1_ST	Q13501	SQSTM1	P48729	CSNK1A1	S233	P228L	228	Missense	distal	-5	no	24.084	23.887	EPSD	TCGA;COSMIC	20.411	Down-regulation
CK1_CK1_CK1-A_CSNK1A1_ST	Q13501	SQSTM1	P48729	CSNK1A1	S275	S277G	277	Missense	proximal	2	no	20.176	20.522	EPSD	TCGA;ICGC;COSMIC	20.411	Gain
CK1_CK1_CK1-A_CSNK1A1_ST	Q13501	SQSTM1	P48729	CSNK1A1	S282	S284A	284	Missense	proximal	2	no	21.022	20.192	EPSD	TCGA;ICGC;COSMIC	20.411	Loss
CK1_CK1_CK1-A_CSNK1A1_ST	Q13501	SQSTM1	P48729	CSNK1A1	S282	S277G	277	Missense	distal	-5	no	21.022	21.316	EPSD	TCGA;ICGC;COSMIC	20.411	Up-regulation
CK1_CK1_CK1-A_CSNK1A1_ST	Q13501	SQSTM1	P48729	CSNK1A1	S282	S276Y	276	Missense	distal	-6	no	21.022	19.974	EPSD	TCGA;ICGC	20.411	Loss
CK1_CK1_CK1-A_CSNK1A1_ST	Q13501	SQSTM1	P48729	CSNK1A1	S282	S277I	277	Missense	distal	-5	no	21.022	20.850	EPSD	TCGA;ICGC	20.411	Down-regulation
CK1_CK1_CK1-A_CSNK1A1_ST	Q13501	SQSTM1	P48729	CSNK1A1	S291	S284A	284	Missense	distal	-7	no	22.276	22.799	EPSD	TCGA;ICGC;COSMIC	20.411	Up-regulation
CK1_CK1_CK1-A_CSNK1A1_ST	Q13501	SQSTM1	P48729	CSNK1A1	S291	P293S	293	Missense	proximal	2	no	22.276	23.291	EPSD	TCGA;ICGC;COSMIC	20.411	Up-regulation
CK1_CK1_CK1-A_CSNK1A1_ST	Q13501	SQSTM1	P48729	CSNK1A1	S328	C331S	331	Missense	distal	3	no	19.140	23.183	EPSD	TCGA;COSMIC	20.411	Gain
CK1_CK1_CK1-A_CSNK1A1_ST	Q13501	SQSTM1	P48729	CSNK1A1	S332	C331S	331	Missense	proximal	-1	no	20.729	21.909	EPSD	TCGA;COSMIC	20.411	Up-regulation
CK1_CK1_CK1-A_CSNK1A1_ST	Q13501	SQSTM1	P48729	CSNK1A1	S349	P348L	348	Missense	proximal	-1	no	22.063	21.779	PhosphoSitePlus	TCGA;COSMIC	20.411	Down-regulation
CK1_CK1_CK1-A_CSNK1A1_ST	Q13501	SQSTM1	P48729	CSNK1A1	S349	E345K	345	Missense	distal	-4	no	22.063	18.366	PhosphoSitePlus	TCGA;COSMIC	20.411	Loss
CK1_CK1_CK1-A_CSNK1A1_ST	Q13501	SQSTM1	P48729	CSNK1A1	S361	L367V	367	Missense	distal	6	no	23.967	23.646	EPSD	TCGA;COSMIC	20.411	Down-regulation
CK1_CK1_CK1-A_CSNK1A1_ST	Q13501	SQSTM1	P48729	CSNK1A1	S361	S365C	365	Missense	distal	4	no	23.967	23.847	EPSD	TCGA	20.411	Down-regulation
CK1_CK1_CK1-A_CSNK1A1_ST	Q13501	SQSTM1	P48729	CSNK1A1	S365	L367V	367	Missense	proximal	2	no	20.464	20.177	EPSD	TCGA;COSMIC	20.411	Loss
CK1_CK1_CK1-A_CSNK1A1_ST	Q13501	SQSTM1	P48729	CSNK1A1	S365	S365C	365	Missense	central	0	yes	20.464	0.000	EPSD	TCGA	20.411	Loss
CK1_CK1_CK1-A_CSNK1A1_ST	Q13501	SQSTM1	P48729	CSNK1A1	S370	L367V	367	Missense	distal	-3	no	19.953	20.864	EPSD	TCGA;COSMIC	20.411	Gain
CK1_CK1_CK1-A_CSNK1A1_ST	P07910	HNRNPC	P48729	CSNK1A1	S107	S100Y	100	Missense	distal	-7	no	23.470	22.002	EPSD	TCGA;ICGC;COSMIC	20.411	Down-regulation
CK1_CK1_CK1-A_CSNK1A1_ST	P07910	HNRNPC	P48729	CSNK1A1	S107	G106W	106	Missense	proximal	-1	no	23.470	21.269	EPSD	TCGA;COSMIC	20.411	Down-regulation
CK1_CK1_CK1-A_CSNK1A1_ST	P07910	HNRNPC	P48729	CSNK1A1	S107	P114L	114	Missense	distal	7	no	23.470	23.318	EPSD	TCGA;ICGC;COSMIC	20.411	Down-regulation
CK1_CK1_CK1-A_CSNK1A1_ST	P07910	HNRNPC	P48729	CSNK1A1	S175	S182Y	182	Missense	distal	7	no	20.315	20.568	EPSD	TCGA;COSMIC	20.411	Gain
CK1_CK1_CK1-A_CSNK1A1_ST	P07910	HNRNPC	P48729	CSNK1A1	S175	S182F	182	Missense	distal	7	no	20.315	20.502	EPSD	TCGA;COSMIC	20.411	Gain
CK1_CK1_CK1-A_CSNK1A1_ST	P07910	HNRNPC	P48729	CSNK1A1	S175	K176N	176	Missense	proximal	1	no	20.315	20.416	EPSD	TCGA;COSMIC	20.411	Gain
CK1_CK1_CK1-A_CSNK1A1_ST	P07910	HNRNPC	P48729	CSNK1A1	S175	R180W	180	Missense	distal	5	no	20.315	20.588	EPSD	TCGA;ICGC;COSMIC;GDSC	20.411	Gain
CK1_CK1_CK1-A_CSNK1A1_ST	P07910	HNRNPC	P48729	CSNK1A1	S175	K170N	170	Missense	distal	-5	no	20.315	21.403	EPSD	TCGA;COSMIC	20.411	Gain
CK1_CK1_CK1-A_CSNK1A1_ST	P07910	HNRNPC	P48729	CSNK1A1	S182	S182Y	182	Missense	central	0	yes	21.299	0.000	EPSD	TCGA;COSMIC	20.411	Loss
CK1_CK1_CK1-A_CSNK1A1_ST	P07910	HNRNPC	P48729	CSNK1A1	S182	S182F	182	Missense	central	0	yes	21.299	0.000	EPSD	TCGA;COSMIC	20.411	Loss
CK1_CK1_CK1-A_CSNK1A1_ST	P07910	HNRNPC	P48729	CSNK1A1	S182	K176N	176	Missense	distal	-6	no	21.299	21.234	EPSD	TCGA;COSMIC	20.411	Down-regulation
CK1_CK1_CK1-A_CSNK1A1_ST	P07910	HNRNPC	P48729	CSNK1A1	S182	R180W	180	Missense	proximal	-2	no	21.299	21.847	EPSD	TCGA;ICGC;COSMIC;GDSC	20.411	Up-regulation
CK1_CK1_CK1-A_CSNK1A1_ST	P07910	HNRNPC	P48729	CSNK1A1	S183	S182Y	182	Missense	proximal	-1	no	23.577	22.691	EPSD	TCGA;COSMIC	20.411	Down-regulation
CK1_CK1_CK1-A_CSNK1A1_ST	P07910	HNRNPC	P48729	CSNK1A1	S183	S182F	182	Missense	proximal	-1	no	23.577	22.874	EPSD	TCGA;COSMIC	20.411	Down-regulation
CK1_CK1_CK1-A_CSNK1A1_ST	P07910	HNRNPC	P48729	CSNK1A1	S183	K176N	176	Missense	distal	-7	no	23.577	22.998	EPSD	TCGA;COSMIC	20.411	Down-regulation
CK1_CK1_CK1-A_CSNK1A1_ST	P07910	HNRNPC	P48729	CSNK1A1	S183	R180W	180	Missense	distal	-3	no	23.577	26.847	EPSD	TCGA;ICGC;COSMIC;GDSC	20.411	Up-regulation
CK1_CK1_CK1-A_CSNK1A1_ST	P07910	HNRNPC	P48729	CSNK1A1	S260	D265N	265	Missense	distal	5	no	21.130	21.377	EPSD;PhosphoSitePlus	TCGA;COSMIC	20.411	Up-regulation
CK1_CK1_CK1-A_CSNK1A1_ST	P07910	HNRNPC	P48729	CSNK1A1	S260	G264W	264	Missense	distal	4	no	21.130	20.854	EPSD;PhosphoSitePlus	TCGA;COSMIC	20.411	Down-regulation
CK1_CK1_CK1-A_CSNK1A1_ST	P07910	HNRNPC	P48729	CSNK1A1	S260	E262K	262	Missense	proximal	2	no	21.130	20.154	EPSD;PhosphoSitePlus	TCGA;COSMIC	20.411	Loss
CK1_CK1_CK1-A_CSNK1A1_ST	P07910	HNRNPC	P48729	CSNK1A1	S299	D305N	305	Missense	distal	6	no	23.605	23.459	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	20.411	Down-regulation
CK1_CK1_CK1-A_CSNK1A1_ST	P07910	HNRNPC	P48729	CSNK1A1	S299	D304N	304	Missense	distal	5	no	23.605	23.851	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	20.411	Up-regulation
CK1_CK1_CK1-A_CSNK1A1_ST	P07910	HNRNPC	P48729	CSNK1A1	S299	D296N	296	Missense	distal	-3	no	23.605	18.325	EPSD;PhosphoSitePlus	TCGA;COSMIC	20.411	Loss
CK1_CK1_CK1-A_CSNK1A1_ST	P07910	HNRNPC	P48729	CSNK1A1	S299	N301D	301	Missense	proximal	2	no	23.605	24.798	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	20.411	Up-regulation
CK1_CK1_CK1-A_CSNK1A1_ST	Q8TB45	DEPTOR	P48729	CSNK1A1	T149	P146S	146	Missense	distal	-3	no	15.674	21.862	EPSD;PhosphoSitePlus	TCGA;COSMIC	20.411	Gain
CK1_CK1_CK1-A_CSNK1A1_ST	Q8TB45	DEPTOR	P48729	CSNK1A1	S286	F290I	290	Missense	distal	4	no	23.573	23.681	EPSD;PhosphoSitePlus	TCGA;COSMIC	20.411	Up-regulation
CK1_CK1_CK1-A_CSNK1A1_ST	Q8TB45	DEPTOR	P48729	CSNK1A1	S287	F290I	290	Missense	distal	3	no	19.361	20.566	PhosphoSitePlus;EPSD	TCGA;COSMIC	20.411	Gain
CK1_CK1_CK1-A_CSNK1A1_ST	Q8TB45	DEPTOR	P48729	CSNK1A1	T295	F290I	290	Missense	distal	-5	no	19.495	21.223	EPSD	TCGA;COSMIC	20.411	Gain
CK1_CK1_CK1-A_CSNK1A1_ST	Q04206	RELA	P48729	CSNK1A1	S45	E39K	39	Missense	distal	-6	no	22.650	22.371	EPSD	TCGA;ICGC;COSMIC	20.411	Down-regulation
CK1_CK1_CK1-A_CSNK1A1_ST	Q04206	RELA	P48729	CSNK1A1	S45	E49K	49	Missense	distal	4	no	22.650	22.460	EPSD	TCGA;ICGC;COSMIC	20.411	Down-regulation
CK1_CK1_CK1-A_CSNK1A1_ST	Q04206	RELA	P48729	CSNK1A1	S45	G44V	44	Missense	proximal	-1	no	22.650	21.218	EPSD	TCGA;ICGC;COSMIC	20.411	Down-regulation
CK1_CK1_CK1-A_CSNK1A1_ST	Q04206	RELA	P48729	CSNK1A1	S131	R133H	133	Missense	proximal	2	no	21.220	20.494	EPSD	TCGA;ICGC;COSMIC	20.411	Down-regulation
CK1_CK1_CK1-A_CSNK1A1_ST	Q04206	RELA	P48729	CSNK1A1	S131	E127K	127	Missense	distal	-4	no	21.220	17.522	EPSD	TCGA;ICGC;COSMIC	20.411	Loss
CK1_CK1_CK1-A_CSNK1A1_ST	Q04206	RELA	P48729	CSNK1A1	S205	E211D	211	Missense	distal	6	no	20.979	21.204	EPSD	TCGA;ICGC;COSMIC	20.411	Up-regulation
CK1_CK1_CK1-A_CSNK1A1_ST	Q04206	RELA	P48729	CSNK1A1	S205	E211Q	211	Missense	distal	6	no	20.979	20.999	EPSD	TCGA;ICGC;COSMIC	20.411	Up-regulation
CK1_CK1_CK1-A_CSNK1A1_ST	Q04206	RELA	P48729	CSNK1A1	S205	E211K	211	Missense	distal	6	no	20.979	20.891	EPSD	TCGA;ICGC;COSMIC	20.411	Down-regulation
CK1_CK1_CK1-A_CSNK1A1_ST	Q04206	RELA	P48729	CSNK1A1	S205	D210Y	210	Missense	distal	5	no	20.979	21.231	EPSD	TCGA;ICGC;COSMIC	20.411	Up-regulation
CK1_CK1_CK1-A_CSNK1A1_ST	Q04206	RELA	P48729	CSNK1A1	S205	G208S	208	Missense	distal	3	no	20.979	20.531	EPSD	TCGA;ICGC;COSMIC;GDSC;CCLE	20.411	Down-regulation
CK1_CK1_CK1-A_CSNK1A1_ST	Q04206	RELA	P48729	CSNK1A1	S316	F309L	309	Missense	distal	-7	no	21.058	20.795	PhosphoSitePlus	TCGA;ICGC;COSMIC	20.411	Down-regulation
CK1_CK1_CK1-A_CSNK1A1_ST	Q04206	RELA	P48729	CSNK1A1	S316	G320E	320	Missense	distal	4	no	21.058	21.133	PhosphoSitePlus	TCGA;ICGC;COSMIC	20.411	Up-regulation
CK1_CK1_CK1-A_CSNK1A1_ST	O60346	PHLPP1	P48729	CSNK1A1	S534	R536Q	536	Missense	proximal	2	no	20.404	20.695	EPSD	TCGA;COSMIC	20.411	Gain
CK1_CK1_CK1-A_CSNK1A1_ST	O60346	PHLPP1	P48729	CSNK1A1	S1381	A1388V	1388	Missense	distal	7	no	25.473	25.592	EPSD;PhosphoSitePlus	TCGA;COSMIC	20.411	Up-regulation
CK1_CK1_CK1-A_CSNK1A1_ST	P07900	HSP90AA1	P48729	CSNK1A1	T305	P301H	301	Missense	distal	-4	no	21.151	19.768	EPSD	TCGA;ICGC;COSMIC	20.411	Loss
CK1_CK1_CK1-A_CSNK1A1_ST	P07900	HSP90AA1	P48729	CSNK1A1	S476	D472H	472	Missense	distal	-4	no	24.531	19.462	EPSD	TCGA;COSMIC	20.411	Loss
CK1_CK1_CK1-A_CSNK1A1_ST	P17181	IFNAR1	P48729	CSNK1A1	S532	S529F	529	Missense	distal	-3	no	21.791	16.139	EPSD	TCGA;COSMIC	20.411	Loss
CK1_CK1_CK1-A_CSNK1A1_ST	P35222	CTNNB1	P48729	CSNK1A1	S45	S45F	45	Missense	central	0	yes	22.310	0.000	PhosphoSitePlus	TCGA;COSMIC;GDSC;CCLE	20.411	Loss
CK1_CK1_CK1-A_CSNK1A1_ST	P35222	CTNNB1	P48729	CSNK1A1	S45	S45P	45	Missense	central	0	yes	22.310	0.000	PhosphoSitePlus	TCGA;COSMIC;CCLE	20.411	Loss
CK1_CK1_CK1-A_CSNK1A1_ST	P35222	CTNNB1	P48729	CSNK1A1	S45	T41A	41	Missense	distal	-4	no	22.310	22.345	PhosphoSitePlus	TCGA;COSMIC;GDSC;CCLE	20.411	Up-regulation
CK1_CK1_CK1-A_CSNK1A1_ST	P35222	CTNNB1	P48729	CSNK1A1	S45	T41I	41	Missense	distal	-4	no	22.310	21.746	PhosphoSitePlus	TCGA;COSMIC	20.411	Down-regulation
CK1_CK1_CK1-A_CSNK1A1_ST	P35222	CTNNB1	P48729	CSNK1A1	S45	S45Y	45	Missense	central	0	yes	22.310	0.000	PhosphoSitePlus	TCGA;COSMIC	20.411	Loss
CK1_CK1_CK1-A_CSNK1A1_ST	P35222	CTNNB1	P48729	CSNK1A1	S45	T41N	41	Missense	distal	-4	no	22.310	21.201	PhosphoSitePlus	TCGA;COSMIC	20.411	Down-regulation
CK1_CK1_CK1-A_CSNK1A1_ST	P35222	CTNNB1	P48729	CSNK1A1	S45	S45C	45	Missense	central	0	yes	22.310	0.000	PhosphoSitePlus	TCGA;COSMIC;GDSC;CCLE	20.411	Loss
CK1_CK1_CK1-A_CSNK1A1_ST	P35222	CTNNB1	P48729	CSNK1A1	T393	N387K	387	Missense	distal	-6	no	20.357	20.423	EPSD	TCGA;COSMIC	20.411	Gain
CK1_CK1_CK1-A_CSNK1A1_ST	P35222	CTNNB1	P48729	CSNK1A1	T393	E396D	396	Missense	distal	3	no	20.357	20.497	EPSD	TCGA	20.411	Gain
CK1_CK1_CK1-A_CSNK1A1_ST	P35222	CTNNB1	P48729	CSNK1A1	T393	R386G	386	Missense	distal	-7	no	20.357	21.008	EPSD	TCGA;COSMIC	20.411	Gain
CK1_CK1_CK1-A_CSNK1A1_ST	P35222	CTNNB1	P48729	CSNK1A1	T393	K394E	394	Missense	proximal	1	no	20.357	20.817	EPSD	TCGA	20.411	Gain
CK1_CK1_CK1-A_CSNK1A1_ST	P35222	CTNNB1	P48729	CSNK1A1	S552	M553V	553	Missense	proximal	1	no	20.527	20.571	EPSD	TCGA;COSMIC	20.411	Up-regulation
CK1_CK1_CK1-A_CSNK1A1_ST	P35222	CTNNB1	P48729	CSNK1A1	S715	R717H	717	Missense	proximal	2	no	24.180	23.454	EPSD	TCGA;COSMIC	20.411	Down-regulation
CK1_CK1_CK1-A_CSNK1A1_ST	P35222	CTNNB1	P48729	CSNK1A1	S715	P714R	714	Missense	proximal	-1	no	24.180	23.706	EPSD	TCGA;COSMIC	20.411	Down-regulation
CK1_CK1_CK1-A_CSNK1A1_ST	P35222	CTNNB1	P48729	CSNK1A1	S715	P714L	714	Missense	proximal	-1	no	24.180	23.896	EPSD	TCGA;COSMIC	20.411	Down-regulation
CK1_CK1_CK1-A_CSNK1A1_ST	P35222	CTNNB1	P48729	CSNK1A1	S718	R717H	717	Missense	proximal	-1	no	24.815	24.134	EPSD	TCGA;COSMIC	20.411	Down-regulation
CK1_CK1_CK1-A_CSNK1A1_ST	P35222	CTNNB1	P48729	CSNK1A1	S718	P714R	714	Missense	distal	-4	no	24.815	25.474	EPSD	TCGA;COSMIC	20.411	Up-regulation
CK1_CK1_CK1-A_CSNK1A1_ST	P35222	CTNNB1	P48729	CSNK1A1	S718	P714L	714	Missense	distal	-4	no	24.815	23.700	EPSD	TCGA;COSMIC	20.411	Down-regulation
CK1_CK1_CK1-A_CSNK1A1_ST	P62745	RHOB	P48729	CSNK1A1	S73	R70W	70	Missense	distal	-3	no	17.550	20.820	EPSD	TCGA;ICGC;COSMIC	20.411	Gain
CK1_CK1_CK1-A_CSNK1A1_ST	Q9H6E5	TUT1	P48729	CSNK1A1	S115	G118E	118	Missense	distal	3	no	22.193	22.328	EPSD	TCGA;COSMIC	20.411	Up-regulation
CK1_CK1_CK1-A_CSNK1A1_ST	P63104	YWHAZ	P48729	CSNK1A1	S37	G33A	33	Missense	distal	-4	no	23.184	21.418	EPSD	TCGA;ICGC;COSMIC	20.411	Down-regulation
CK1_CK1_CK1-A_CSNK1A1_ST	P63104	YWHAZ	P48729	CSNK1A1	S99	C94S	94	Missense	distal	-5	no	19.658	20.962	EPSD	TCGA;ICGC;COSMIC	20.411	Gain
CK1_CK1_CK1-A_CSNK1A1_ST	P63104	YWHAZ	P48729	CSNK1A1	S207	S210L	210	Missense	distal	3	no	22.466	18.713	EPSD	TCGA;ICGC;COSMIC	20.411	Loss
CK1_CK1_CK1-A_CSNK1A1_ST	P63104	YWHAZ	P48729	CSNK1A1	S207	S207I	207	Missense	central	0	yes	22.466	0.000	EPSD	TCGA;ICGC;COSMIC	20.411	Loss
CK1_CK1_CK1-A_CSNK1A1_ST	P63104	YWHAZ	P48729	CSNK1A1	S207	K212T	212	Missense	distal	5	no	22.466	22.266	EPSD	TCGA;ICGC;COSMIC	20.411	Down-regulation
CK1_CK1_CK1-A_CSNK1A1_ST	P63104	YWHAZ	P48729	CSNK1A1	S210	S210L	210	Missense	central	0	yes	22.266	0.000	EPSD	TCGA;ICGC;COSMIC	20.411	Loss
CK1_CK1_CK1-A_CSNK1A1_ST	P63104	YWHAZ	P48729	CSNK1A1	S210	S207I	207	Missense	distal	-3	no	22.266	18.285	EPSD	TCGA;ICGC;COSMIC	20.411	Loss
CK1_CK1_CK1-A_CSNK1A1_ST	P63104	YWHAZ	P48729	CSNK1A1	S210	K212T	212	Missense	proximal	2	no	22.266	22.500	EPSD	TCGA;ICGC;COSMIC	20.411	Up-regulation
CK1_CK1_CK1-A_CSNK1A1_ST	P63104	YWHAZ	P48729	CSNK1A1	S210	I217R	217	Missense	distal	7	no	22.266	22.464	EPSD	TCGA;ICGC;COSMIC	20.411	Up-regulation
CK1_CK1_CK1-A_CSNK1A1_ST	P56537	EIF6	P48729	CSNK1A1	S174	L177V	177	Missense	distal	3	no	25.943	27.110	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	20.411	Up-regulation
CK1_CK1_CK1-A_CSNK1A1_ST	P56537	EIF6	P48729	CSNK1A1	S174	D171N	171	Missense	distal	-3	no	25.943	20.663	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	20.411	Down-regulation
CK1_CK1_CK1-A_CSNK1A1_ST	P56537	EIF6	P48729	CSNK1A1	S175	L177V	177	Missense	proximal	2	no	25.296	25.009	PhosphoSitePlus;EPSD	TCGA;ICGC;COSMIC	20.411	Down-regulation
CK1_CK1_CK1-A_CSNK1A1_ST	P56537	EIF6	P48729	CSNK1A1	S175	D171N	171	Missense	distal	-4	no	25.296	21.558	PhosphoSitePlus;EPSD	TCGA;ICGC;COSMIC	20.411	Down-regulation
CK1_CK1_CK1-A_CSNK1A1_ST	P30304	CDC25A	P48729	CSNK1A1	S79	R73K	73	Missense	distal	-6	no	26.558	26.137	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	20.411	Down-regulation
CK1_CK1_CK1-A_CSNK1A1_ST	P30304	CDC25A	P48729	CSNK1A1	S79	E78K	78	Missense	proximal	-1	no	26.558	24.916	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	20.411	Down-regulation
CK1_CK1_CK1-A_CSNK1A1_ST	P30304	CDC25A	P48729	CSNK1A1	S82	D87Y	87	Missense	distal	5	no	23.603	23.855	PhosphoSitePlus;EPSD	TCGA;ICGC;COSMIC	20.411	Up-regulation
CK1_CK1_CK1-A_CSNK1A1_ST	P30304	CDC25A	P48729	CSNK1A1	S82	P89L	89	Missense	distal	7	no	23.603	23.451	PhosphoSitePlus;EPSD	TCGA;ICGC;COSMIC	20.411	Down-regulation
CK1_CK1_CK1-A_CSNK1A1_ST	P30304	CDC25A	P48729	CSNK1A1	S82	E78K	78	Missense	distal	-4	no	23.603	19.906	PhosphoSitePlus;EPSD	TCGA;ICGC;COSMIC	20.411	Loss
CK1_CK1_CK1-A_CSNK1A1_ST	P42892	ECE1	P48729	CSNK1A1	S633	W630C	630	Missense	distal	-3	no	24.459	21.083	EPSD	TCGA;COSMIC	20.411	Down-regulation
CK1_CK1_CK1-A_CSNK1A1_ST	P42892	ECE1	P48729	CSNK1A1	S633	P628S	628	Missense	distal	-5	no	24.459	24.891	EPSD	TCGA;COSMIC	20.411	Up-regulation
CK1_CK1_CK1-A_CSNK1A1_ST	P42892	ECE1	P48729	CSNK1A1	S633	V635M	635	Missense	proximal	2	no	24.459	24.905	EPSD	TCGA;COSMIC	20.411	Up-regulation
CK1_CK1_CK1-A_CSNK1A1_ST	P42892	ECE1	P48729	CSNK1A1	S633	S634F	634	Missense	proximal	1	no	24.459	24.402	EPSD	TCGA;COSMIC	20.411	Down-regulation
CK1_CK1_CK1-A_CSNK1A1_ST	P42892	ECE1	P48729	CSNK1A1	S633	K631N	631	Missense	proximal	-2	no	24.459	23.532	EPSD	TCGA;COSMIC	20.411	Down-regulation
CK1_CK1_CK1-A_CSNK1A1_ST	O94916	NFAT5	P48729	CSNK1A1	S7	D14G	14	Missense	distal	7	no	20.558	20.618	EPSD	TCGA;ICGC;COSMIC	20.411	Up-regulation
CK1_CK1_CK1-A_CSNK1A1_ST	O14503	BHLHE40	P48729	CSNK1A1	S235	D242H	242	Missense	distal	7	no	23.462	23.733	EPSD	TCGA;ICGC;COSMIC	20.411	Up-regulation
CK1_CK1_CK1-A_CSNK1A1_ST	O14503	BHLHE40	P48729	CSNK1A1	S235	S230L	230	Missense	distal	-5	no	23.462	22.833	EPSD	TCGA;ICGC;CCLE	20.411	Down-regulation
CK1_CK1_CK1-A_CSNK1A1_ST	O14503	BHLHE40	P48729	CSNK1A1	S237	D242H	242	Missense	distal	5	no	24.300	24.598	EPSD	TCGA;ICGC;COSMIC	20.411	Up-regulation
CK1_CK1_CK1-A_CSNK1A1_ST	O14503	BHLHE40	P48729	CSNK1A1	S237	S230L	230	Missense	distal	-7	no	24.300	23.620	EPSD	TCGA;ICGC;CCLE	20.411	Down-regulation
CK1_CK1_CK1-A_CSNK1A1_ST	O14503	BHLHE40	P48729	CSNK1A1	T239	D242H	242	Missense	distal	3	no	20.851	16.304	EPSD	TCGA;ICGC;COSMIC	20.411	Loss
CK1_CK1_CK1-A_CSNK1A1_ST	O14503	BHLHE40	P48729	CSNK1A1	T239	G246R	246	Missense	distal	7	no	20.851	20.937	EPSD	TCGA;ICGC;COSMIC	20.411	Up-regulation
CK1_CK1_CK1-A_CSNK1A1_ST	O14503	BHLHE40	P48729	CSNK1A1	T239	G246E	246	Missense	distal	7	no	20.851	20.705	EPSD	TCGA;ICGC;COSMIC	20.411	Down-regulation
CK1_CK1_CK1-A_CSNK1A1_ST	O14503	BHLHE40	P48729	CSNK1A1	T241	D242H	242	Missense	proximal	1	no	21.911	21.597	EPSD	TCGA;ICGC;COSMIC	20.411	Down-regulation
CK1_CK1_CK1-A_CSNK1A1_ST	O14503	BHLHE40	P48729	CSNK1A1	T241	G246R	246	Missense	distal	5	no	21.911	22.009	EPSD	TCGA;ICGC;COSMIC	20.411	Up-regulation
CK1_CK1_CK1-A_CSNK1A1_ST	O14503	BHLHE40	P48729	CSNK1A1	T241	G246E	246	Missense	distal	5	no	21.911	21.567	EPSD	TCGA;ICGC;COSMIC	20.411	Down-regulation
CK1_CK1_CK1-A_CSNK1A1_ST	O14503	BHLHE40	P48729	CSNK1A1	S243	D242H	242	Missense	proximal	-1	no	21.002	19.430	PhosphoSitePlus	TCGA;ICGC;COSMIC	20.411	Loss
CK1_CK1_CK1-A_CSNK1A1_ST	O14503	BHLHE40	P48729	CSNK1A1	S243	G246R	246	Missense	distal	3	no	21.002	18.111	PhosphoSitePlus	TCGA;ICGC;COSMIC	20.411	Loss
CK1_CK1_CK1-A_CSNK1A1_ST	O14503	BHLHE40	P48729	CSNK1A1	S243	G246E	246	Missense	distal	3	no	21.002	21.136	PhosphoSitePlus	TCGA;ICGC;COSMIC	20.411	Up-regulation
CK1_CK1_CK1-A_CSNK1A1_ST	O14503	BHLHE40	P48729	CSNK1A1	S249	D242H	242	Missense	distal	-7	no	22.703	21.359	EPSD	TCGA;ICGC;COSMIC	20.411	Down-regulation
CK1_CK1_CK1-A_CSNK1A1_ST	O14503	BHLHE40	P48729	CSNK1A1	S249	S256C	256	Missense	distal	7	no	22.703	22.856	EPSD	TCGA;ICGC	20.411	Up-regulation
CK1_CK1_CK1-A_CSNK1A1_ST	O14503	BHLHE40	P48729	CSNK1A1	S249	G246R	246	Missense	distal	-3	no	22.703	20.168	EPSD	TCGA;ICGC;COSMIC	20.411	Loss
CK1_CK1_CK1-A_CSNK1A1_ST	O14503	BHLHE40	P48729	CSNK1A1	S249	G246E	246	Missense	distal	-3	no	22.703	22.290	EPSD	TCGA;ICGC;COSMIC	20.411	Down-regulation
CK1_CK1_CK1-A_CSNK1A1_ST	O14503	BHLHE40	P48729	CSNK1A1	S249	R255C	255	Missense	distal	6	no	22.703	22.471	EPSD	TCGA;ICGC;COSMIC	20.411	Down-regulation
CK1_CK1_CK1-A_CSNK1A1_ST	P37840	SNCA	P48729	CSNK1A1	S87	F94V	94	Missense	distal	7	no	21.035	21.046	PhosphoSitePlus;EPSD	TCGA;ICGC;COSMIC	20.411	Up-regulation
TKL_RIPK_RIPK1_ST	Q13546	RIPK1	Q13546	RIPK1	S20	D24G	24	Missense	distal	4	no	5.886	5.856	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	2.812	Down-regulation
TKL_RIPK_RIPK1_ST	Q13546	RIPK1	Q13546	RIPK1	S161	K167E	167	Missense	distal	6	no	6.228	6.276	EPSD;PhosphoSitePlus	TCGA;ICGC	2.812	Up-regulation
TKL_RIPK_RIPK1_ST	Q13546	RIPK1	Q13546	RIPK1	S166	K167E	167	Missense	proximal	1	no	6.739	6.677	EPSD;PhosphoSitePlus	TCGA;ICGC	2.812	Down-regulation
TKL_RIPK_RIPK1_ST	Q13546	RIPK1	Q13546	RIPK1	S291	P287L	287	Missense	distal	-4	no	3.584	3.556	EPSD	TCGA;ICGC;COSMIC	2.812	Down-regulation
TKL_RIPK_RIPK1_ST	Q13546	RIPK1	Q13546	RIPK1	S291	S296N	296	Missense	distal	5	no	3.584	3.022	EPSD	TCGA;ICGC	2.812	Down-regulation
TKL_RIPK_RIPK1_ST	Q13546	RIPK1	Q13546	RIPK1	S291	K284T	284	Missense	distal	-7	no	3.584	3.547	EPSD	TCGA;ICGC;COSMIC	2.812	Down-regulation
TKL_RIPK_RIPK1_ST	Q13546	RIPK1	Q13546	RIPK1	S333	R332W	332	Missense	proximal	-1	no	2.990	2.992	EPSD	TCGA;ICGC;COSMIC	2.812	Up-regulation
TKL_RIPK_RIPK1_ST	Q13546	RIPK1	Q13546	RIPK1	S333	T337I	337	Missense	distal	4	no	2.990	3.167	EPSD	TCGA;ICGC;COSMIC	2.812	Up-regulation
TKL_RIPK_RIPK1_ST	Q13546	RIPK1	Q13546	RIPK1	S357	M351I	351	Missense	distal	-6	no	2.756	2.815	EPSD	TCGA;ICGC;COSMIC	2.812	Gain
TKL_RIPK_RIPK1_ST	Q5VWQ8	DAB2IP	Q13546	RIPK1	S876	A883V	883	Missense	distal	7	no	2.973	2.897	EPSD	TCGA;ICGC;COSMIC	2.812	Down-regulation
CMGC_RCK_MAK_ICK_ST	P46379	BAG6	Q9UPZ9	ICK	T92	S99Y	99	Missense	distal	7	no	2.939	3.023	EPSD	TCGA;ICGC;COSMIC	2.314	Up-regulation
CMGC_RCK_MAK_ICK_ST	P46379	BAG6	Q9UPZ9	ICK	S722	S715F	715	Missense	distal	-7	no	4.079	4.123	EPSD	TCGA;COSMIC	2.314	Up-regulation
CMGC_RCK_MAK_ICK_ST	P46379	BAG6	Q9UPZ9	ICK	T978	P976S	976	Missense	proximal	-2	no	4.746	1.758	EPSD	TCGA;COSMIC	2.314	Loss
CMGC_RCK_MAK_ICK_ST	P46379	BAG6	Q9UPZ9	ICK	T1053	R1051H	1051	Missense	proximal	-2	no	4.550	4.188	EPSD	TCGA;COSMIC	2.314	Down-regulation
CMGC_RCK_MAK_ICK_ST	P46379	BAG6	Q9UPZ9	ICK	T1080	A1073T	1073	Missense	distal	-7	no	11.305	11.372	PhosphoSitePlus	TCGA;COSMIC	2.314	Up-regulation
CMGC_RCK_MAK_ICK_ST	P46379	BAG6	Q9UPZ9	ICK	T1080	E1083K	1083	Missense	distal	3	no	11.305	11.291	PhosphoSitePlus	TCGA;COSMIC	2.314	Down-regulation
CMGC_RCK_MAK_ICK_ST	P46379	BAG6	Q9UPZ9	ICK	T1080	R1087W	1087	Missense	distal	7	no	11.305	11.124	PhosphoSitePlus	TCGA;COSMIC	2.314	Down-regulation
CMGC_RCK_MAK_ICK_ST	P46379	BAG6	Q9UPZ9	ICK	T1080	R1087Q	1087	Missense	distal	7	no	11.305	11.154	PhosphoSitePlus	TCGA;COSMIC	2.314	Down-regulation
CMGC_RCK_MAK_ICK_ST	P46379	BAG6	Q9UPZ9	ICK	S1084	E1083K	1083	Missense	proximal	-1	no	3.903	3.984	EPSD	TCGA;COSMIC	2.314	Up-regulation
CMGC_RCK_MAK_ICK_ST	P46379	BAG6	Q9UPZ9	ICK	S1084	R1087W	1087	Missense	distal	3	no	3.903	3.919	EPSD	TCGA;COSMIC	2.314	Up-regulation
CMGC_RCK_MAK_ICK_ST	P46379	BAG6	Q9UPZ9	ICK	S1084	R1087Q	1087	Missense	distal	3	no	3.903	3.878	EPSD	TCGA;COSMIC	2.314	Down-regulation
CMGC_RCK_MAK_ICK_ST	Q8N122	RPTOR	Q9UPZ9	ICK	T714	S719F	719	Missense	distal	5	no	3.343	3.238	EPSD	TCGA;ICGC;COSMIC	2.314	Down-regulation
CMGC_RCK_MAK_ICK_ST	Q8N122	RPTOR	Q9UPZ9	ICK	T714	C713F	713	Missense	proximal	-1	no	3.343	3.290	EPSD	TCGA	2.314	Down-regulation
CMGC_RCK_MAK_ICK_ST	Q8N122	RPTOR	Q9UPZ9	ICK	T714	R709Q	709	Missense	distal	-5	no	3.343	3.267	EPSD	TCGA;COSMIC	2.314	Down-regulation
CMGC_RCK_MAK_ICK_ST	Q8N122	RPTOR	Q9UPZ9	ICK	S719	S719F	719	Missense	central	0	yes	4.089	0.000	EPSD	TCGA;ICGC;COSMIC	2.314	Loss
CMGC_RCK_MAK_ICK_ST	Q8N122	RPTOR	Q9UPZ9	ICK	S719	C713F	713	Missense	distal	-6	no	4.089	4.120	EPSD	TCGA	2.314	Up-regulation
CMGC_RCK_MAK_ICK_ST	Q8N122	RPTOR	Q9UPZ9	ICK	S719	Y723C	723	Missense	distal	4	no	4.089	4.093	EPSD	TCGA;COSMIC	2.314	Up-regulation
CMGC_RCK_MAK_ICK_ST	Q8N122	RPTOR	Q9UPZ9	ICK	S719	G724E	724	Missense	distal	5	no	4.089	3.965	EPSD	TCGA;COSMIC	2.314	Down-regulation
CMGC_RCK_MAK_ICK_ST	Q8N122	RPTOR	Q9UPZ9	ICK	S721	S719F	719	Missense	proximal	-2	no	3.395	4.038	EPSD	TCGA;ICGC;COSMIC	2.314	Up-regulation
CMGC_RCK_MAK_ICK_ST	Q8N122	RPTOR	Q9UPZ9	ICK	S721	Y723C	723	Missense	proximal	2	no	3.395	3.384	EPSD	TCGA;COSMIC	2.314	Down-regulation
CMGC_RCK_MAK_ICK_ST	Q8N122	RPTOR	Q9UPZ9	ICK	S721	G724E	724	Missense	distal	3	no	3.395	3.404	EPSD	TCGA;COSMIC	2.314	Up-regulation
CMGC_RCK_MAK_ICK_ST	Q8N122	RPTOR	Q9UPZ9	ICK	S863	T857M	857	Missense	distal	-6	no	2.727	2.699	EPSD	TCGA;COSMIC	2.314	Down-regulation
CMGC_RCK_MAK_ICK_ST	Q8N122	RPTOR	Q9UPZ9	ICK	S881	S877F	877	Missense	distal	-4	no	3.920	3.909	EPSD	TCGA;COSMIC	2.314	Down-regulation
CMGC_RCK_MAK_ICK_ST	Q8N122	RPTOR	Q9UPZ9	ICK	S881	P879L	879	Missense	proximal	-2	no	3.920	1.228	EPSD	TCGA;COSMIC	2.314	Loss
CMGC_RCK_MAK_ICK_ST	Q8N122	RPTOR	Q9UPZ9	ICK	S920	R927L	927	Missense	distal	7	no	2.681	2.439	EPSD	TCGA;COSMIC	2.314	Down-regulation
STE_STE20_YSK_STK24_ST	Q9Y6E0	STK24	Q9Y6E0	STK24	T190	P195S	195	Missense	distal	5	no	7.434	7.139	PhosphoSitePlus	TCGA;ICGC;COSMIC	2.432	Down-regulation
STE_STE20_YSK_STK24_ST	Q9Y6E0	STK24	Q9Y6E0	STK24	T190	T190A	190	Missense	central	0	yes	7.434	0.000	PhosphoSitePlus	TCGA;COSMIC	2.432	Loss
STE_STE20_YSK_STK24_ST	Q9Y6E0	STK24	Q9Y6E0	STK24	S373	I367T	367	Missense	distal	-6	no	3.411	3.427	EPSD	TCGA	2.432	Up-regulation
STE_STE20_YSK_STK24_ST	Q9Y2H1	STK38L	Q9Y6E0	STK24	T8	A5T	5	Missense	distal	-3	no	3.132	3.103	EPSD	TCGA;ICGC;COSMIC	2.432	Down-regulation
STE_STE20_YSK_STK24_ST	Q9Y2H1	STK38L	Q9Y6E0	STK24	T8	N15S	15	Missense	distal	7	no	3.132	3.103	EPSD	TCGA;ICGC;COSMIC	2.432	Down-regulation
STE_STE20_YSK_STK24_ST	Q9Y2H1	STK38L	Q9Y6E0	STK24	T17	E19K	19	Missense	proximal	2	no	2.315	2.830	EPSD	TCGA;ICGC;COSMIC	2.432	Gain
STE_STE20_YSK_STK24_ST	Q9Y2H1	STK38L	Q9Y6E0	STK24	S282	A280V	280	Missense	proximal	-2	no	3.758	3.764	EPSD	TCGA;COSMIC	2.432	Up-regulation
STE_STE20_YSK_STK24_ST	Q9Y2H1	STK38L	Q9Y6E0	STK24	T442	W436L	436	Missense	distal	-6	no	8.532	8.493	PhosphoSitePlus	TCGA;ICGC;COSMIC	2.432	Down-regulation
STE_STE20_YSK_STK24_ST	Q9Y2H1	STK38L	Q9Y6E0	STK24	T442	K444T	444	Missense	proximal	2	no	8.532	8.061	PhosphoSitePlus	TCGA;ICGC	2.432	Down-regulation
STE_STE20_YSK_STK24_ST	Q7L7X3	TAOK1	Q9Y6E0	STK24	S60	A55V	55	Missense	distal	-5	no	3.171	3.084	EPSD	TCGA;ICGC;COSMIC	2.432	Down-regulation
STE_STE20_YSK_STK24_ST	Q7L7X3	TAOK1	Q9Y6E0	STK24	S60	M59V	59	Missense	proximal	-1	no	3.171	3.176	EPSD	TCGA;ICGC;COSMIC	2.432	Up-regulation
STE_STE20_YSK_STK24_ST	Q7L7X3	TAOK1	Q9Y6E0	STK24	S66	M59V	59	Missense	distal	-7	no	3.265	3.264	EPSD	TCGA;ICGC;COSMIC	2.432	Down-regulation
STE_STE20_YSK_STK24_ST	Q7L7X3	TAOK1	Q9Y6E0	STK24	S717	K716M	716	Missense	proximal	-1	no	3.033	3.059	EPSD	TCGA;ICGC;COSMIC	2.432	Up-regulation
STE_STE20_YSK_STK24_ST	Q7L7X3	TAOK1	Q9Y6E0	STK24	S717	Q711H	711	Missense	distal	-6	no	3.033	3.034	EPSD	TCGA;ICGC;COSMIC	2.432	Up-regulation
CMGC_DYRK_DYRK2_DYRK2_ST	Q13541	EIF4EBP1	Q92630	DYRK2	T68	L75M	75	Missense	distal	7	no	47.168	48.626	EPSD	TCGA;ICGC	45.963	Up-regulation
CMGC_DYRK_DYRK2_DYRK2_ST	Q13541	EIF4EBP1	Q92630	DYRK2	T70	L75M	75	Missense	distal	5	no	56.720	57.193	EPSD	TCGA;ICGC	45.963	Up-regulation
CMGC_DYRK_DYRK2_DYRK2_ST	Q13541	EIF4EBP1	Q92630	DYRK2	S83	S86N	86	Missense	distal	3	no	57.978	58.570	EPSD	TCGA;ICGC;COSMIC	45.963	Up-regulation
CMGC_DYRK_DYRK2_DYRK2_ST	Q13541	EIF4EBP1	Q92630	DYRK2	S101	A107V	107	Missense	distal	6	no	90.431	90.826	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC;GDSC;CCLE	45.963	Up-regulation
CMGC_DYRK_DYRK2_DYRK2_ST	O43255	SIAH2	Q92630	DYRK2	S68	H71D	71	Missense	distal	3	no	79.555	82.263	PhosphoSitePlus;EPSD	TCGA;ICGC;COSMIC	45.963	Up-regulation
CMGC_DYRK_DYRK2_DYRK2_ST	O43255	SIAH2	Q92630	DYRK2	S68	Q70H	70	Missense	proximal	2	no	79.555	78.188	PhosphoSitePlus;EPSD	TCGA;ICGC;COSMIC	45.963	Down-regulation
CMGC_DYRK_DYRK2_DYRK2_ST	Q9Y2V2	CARHSP1	Q92630	DYRK2	S2	S3C	3	Missense	proximal	1	no	61.343	27.626	EPSD	TCGA;ICGC;COSMIC	45.963	Loss
CMGC_DYRK_DYRK2_DYRK2_ST	Q9Y2V2	CARHSP1	Q92630	DYRK2	T23	R25W	25	Missense	proximal	2	no	48.159	47.684	EPSD	TCGA;ICGC;COSMIC	45.963	Down-regulation
CMGC_DYRK_DYRK2_DYRK2_ST	Q9Y2V2	CARHSP1	Q92630	DYRK2	T23	R27C	27	Missense	distal	4	no	48.159	48.297	EPSD	TCGA;ICGC;COSMIC	45.963	Up-regulation
CMGC_DYRK_DYRK2_DYRK2_ST	Q9Y2V2	CARHSP1	Q92630	DYRK2	T23	R29H	29	Missense	distal	6	no	48.159	47.734	EPSD	TCGA;ICGC	45.963	Down-regulation
CMGC_DYRK_DYRK2_DYRK2_ST	Q9Y2V2	CARHSP1	Q92630	DYRK2	S30	R25W	25	Missense	distal	-5	no	76.431	76.832	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	45.963	Up-regulation
CMGC_DYRK_DYRK2_DYRK2_ST	Q9Y2V2	CARHSP1	Q92630	DYRK2	S30	R27C	27	Missense	distal	-3	no	76.431	67.090	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	45.963	Down-regulation
CMGC_DYRK_DYRK2_DYRK2_ST	Q9Y2V2	CARHSP1	Q92630	DYRK2	S30	G36S	36	Missense	distal	6	no	76.431	76.563	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	45.963	Up-regulation
CMGC_DYRK_DYRK2_DYRK2_ST	Q9Y2V2	CARHSP1	Q92630	DYRK2	S30	R29H	29	Missense	proximal	-1	no	76.431	78.955	EPSD;PhosphoSitePlus	TCGA;ICGC	45.963	Up-regulation
CMGC_DYRK_DYRK2_DYRK2_ST	Q9Y2V2	CARHSP1	Q92630	DYRK2	S32	R25W	25	Missense	distal	-7	no	78.676	79.329	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	45.963	Up-regulation
CMGC_DYRK_DYRK2_DYRK2_ST	Q9Y2V2	CARHSP1	Q92630	DYRK2	S32	R27C	27	Missense	distal	-5	no	78.676	78.635	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	45.963	Down-regulation
CMGC_DYRK_DYRK2_DYRK2_ST	Q9Y2V2	CARHSP1	Q92630	DYRK2	S32	G36S	36	Missense	distal	4	no	78.676	78.705	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	45.963	Up-regulation
CMGC_DYRK_DYRK2_DYRK2_ST	Q9Y2V2	CARHSP1	Q92630	DYRK2	S32	R29H	29	Missense	distal	-3	no	78.676	58.899	EPSD;PhosphoSitePlus	TCGA;ICGC	45.963	Down-regulation
CMGC_DYRK_DYRK2_DYRK2_ST	Q9Y2V2	CARHSP1	Q92630	DYRK2	S41	T48M	48	Missense	distal	7	no	79.293	78.180	PhosphoSitePlus;EPSD	TCGA;ICGC;COSMIC	45.963	Down-regulation
CMGC_DYRK_DYRK2_DYRK2_ST	Q9Y2V2	CARHSP1	Q92630	DYRK2	S41	P44L	44	Missense	distal	3	no	79.293	77.521	PhosphoSitePlus;EPSD	TCGA;ICGC;COSMIC	45.963	Down-regulation
CMGC_DYRK_DYRK2_DYRK2_ST	Q9Y2V2	CARHSP1	Q92630	DYRK2	S41	G36S	36	Missense	distal	-5	no	79.293	78.896	PhosphoSitePlus;EPSD	TCGA;ICGC;COSMIC	45.963	Down-regulation
CMGC_DYRK_DYRK2_DYRK2_ST	Q9Y2V2	CARHSP1	Q92630	DYRK2	T54	R56W	56	Missense	proximal	2	no	48.708	48.232	EPSD	TCGA;ICGC;COSMIC	45.963	Down-regulation
CMGC_DYRK_DYRK2_DYRK2_ST	Q9Y2V2	CARHSP1	Q92630	DYRK2	T54	T48M	48	Missense	distal	-6	no	48.708	48.758	EPSD	TCGA;ICGC;COSMIC	45.963	Up-regulation
CMGC_DYRK_DYRK2_DYRK2_ST	Q9Y2V2	CARHSP1	Q92630	DYRK2	T54	P61S	61	Missense	distal	7	no	48.708	45.652	EPSD	TCGA;ICGC;COSMIC	45.963	Loss
CMGC_DYRK_DYRK2_DYRK2_ST	Q9Y2V2	CARHSP1	Q92630	DYRK2	S141	G134R	134	Missense	distal	-7	no	54.435	54.010	EPSD	TCGA;ICGC;COSMIC	45.963	Down-regulation
CMGC_DYRK_DYRK2_DYRK2_ST	O43602	DCX	Q92630	DYRK2	S147	V150M	150	Missense	distal	3	no	54.837	54.482	EPSD	TCGA;ICGC	45.963	Down-regulation
CMGC_DYRK_DYRK2_DYRK2_ST	O75449	KATNA1	Q92630	DYRK2	S109	E105Q	105	Missense	distal	-4	no	90.013	94.095	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	45.963	Up-regulation
CMGC_DYRK_DYRK2_DYRK2_ST	O75449	KATNA1	Q92630	DYRK2	T133	R129C	129	Missense	distal	-4	no	72.220	72.197	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC;CCLE	45.963	Down-regulation
CMGC_DYRK_DYRK2_DYRK2_ST	O75449	KATNA1	Q92630	DYRK2	T133	N128S	128	Missense	distal	-5	no	72.220	72.031	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	45.963	Down-regulation
CMGC_DYRK_DYRK2_DYRK2_ST	O75449	KATNA1	Q92630	DYRK2	T441	R436C	436	Missense	distal	-5	no	47.492	47.450	EPSD	TCGA;ICGC;COSMIC	45.963	Down-regulation
CMGC_DYRK_DYRK2_DYRK2_ST	O75449	KATNA1	Q92630	DYRK2	T457	H454R	454	Missense	distal	-3	no	32.268	52.045	EPSD	TCGA;ICGC;COSMIC	45.963	Gain
CMGC_DYRK_DYRK2_DYRK2_ST	P04637	TP53	Q92630	DYRK2	S9	P4L	4	Missense	distal	-5	no	56.920	58.159	EPSD	TCGA;ICGC;COSMIC	45.963	Up-regulation
CMGC_DYRK_DYRK2_DYRK2_ST	P04637	TP53	Q92630	DYRK2	S33	P27S	27	Missense	distal	-6	no	50.772	50.924	EPSD	TCGA;ICGC;COSMIC	45.963	Up-regulation
CMGC_DYRK_DYRK2_DYRK2_ST	P04637	TP53	Q92630	DYRK2	S33	P27L	27	Missense	distal	-6	no	50.772	51.092	EPSD	TCGA;ICGC;COSMIC;GDSC;CCLE	45.963	Up-regulation
CMGC_DYRK_DYRK2_DYRK2_ST	P04637	TP53	Q92630	DYRK2	S46	D48N	48	Missense	proximal	2	no	78.736	79.202	PhosphoSitePlus	TCGA;ICGC;COSMIC;GDSC;CCLE	45.963	Up-regulation
CMGC_DYRK_DYRK2_DYRK2_ST	P04637	TP53	Q92630	DYRK2	T81	A79V	79	Missense	proximal	-2	no	57.238	60.949	EPSD	TCGA;ICGC;COSMIC	45.963	Up-regulation
CMGC_DYRK_DYRK2_DYRK2_ST	P04637	TP53	Q92630	DYRK2	T81	P77L	77	Missense	distal	-4	no	57.238	53.804	EPSD	TCGA;ICGC;COSMIC	45.963	Down-regulation
CMGC_DYRK_DYRK2_DYRK2_ST	P04637	TP53	Q92630	DYRK2	T81	P82L	82	Missense	proximal	1	no	57.238	9.024	EPSD	TCGA;ICGC;COSMIC	45.963	Loss
CMGC_DYRK_DYRK2_DYRK2_ST	P04637	TP53	Q92630	DYRK2	T81	A74T	74	Missense	distal	-7	no	57.238	58.454	EPSD	TCGA;ICGC;COSMIC	45.963	Up-regulation
CMGC_DYRK_DYRK2_DYRK2_ST	P04637	TP53	Q92630	DYRK2	S149	L145R	145	Missense	distal	-4	no	41.068	50.489	EPSD	TCGA;ICGC;COSMIC;GDSC;CCLE	45.963	Gain
CMGC_DYRK_DYRK2_DYRK2_ST	P04637	TP53	Q92630	DYRK2	T150	W146S	146	Missense	distal	-4	no	53.573	55.729	EPSD	TCGA;ICGC;COSMIC	45.963	Up-regulation
CMGC_DYRK_DYRK2_DYRK2_ST	P04637	TP53	Q92630	DYRK2	T150	P152L	152	Missense	proximal	2	no	53.573	52.611	EPSD	TCGA;ICGC;COSMIC;GDSC;CCLE	45.963	Down-regulation
CMGC_DYRK_DYRK2_DYRK2_ST	P04637	TP53	Q92630	DYRK2	T150	D148N	148	Missense	proximal	-2	no	53.573	55.690	EPSD	TCGA;ICGC;COSMIC	45.963	Up-regulation
CMGC_DYRK_DYRK2_DYRK2_ST	P04637	TP53	Q92630	DYRK2	T150	P151H	151	Missense	proximal	1	no	53.573	-55.656	EPSD	TCGA;ICGC;COSMIC;GDSC;CCLE	45.963	Loss
CMGC_DYRK_DYRK2_DYRK2_ST	P04637	TP53	Q92630	DYRK2	T150	P151A	151	Missense	proximal	1	no	53.573	-18.919	EPSD	TCGA;ICGC;COSMIC;CCLE	45.963	Loss
CMGC_DYRK_DYRK2_DYRK2_ST	P04637	TP53	Q92630	DYRK2	T150	R156P	156	Missense	distal	6	no	53.573	53.794	EPSD	TCGA;ICGC;COSMIC;GDSC;CCLE	45.963	Up-regulation
CMGC_DYRK_DYRK2_DYRK2_ST	P04637	TP53	Q92630	DYRK2	T150	V143A	143	Missense	distal	-7	no	53.573	52.310	EPSD	TCGA;ICGC;COSMIC;GDSC;CCLE	45.963	Down-regulation
CMGC_DYRK_DYRK2_DYRK2_ST	P04637	TP53	Q92630	DYRK2	T150	P151S	151	Missense	proximal	1	no	53.573	24.173	EPSD	TCGA;ICGC;COSMIC;GDSC;CCLE	45.963	Loss
CMGC_DYRK_DYRK2_DYRK2_ST	P04637	TP53	Q92630	DYRK2	T150	V157F	157	Missense	distal	7	no	53.573	48.827	EPSD	TCGA;ICGC;COSMIC;GDSC;CCLE	45.963	Down-regulation
CMGC_DYRK_DYRK2_DYRK2_ST	P04637	TP53	Q92630	DYRK2	T150	V157G	157	Missense	distal	7	no	53.573	51.558	EPSD	TCGA;ICGC;COSMIC	45.963	Down-regulation
CMGC_DYRK_DYRK2_DYRK2_ST	P04637	TP53	Q92630	DYRK2	T150	V157D	157	Missense	distal	7	no	53.573	52.999	EPSD	TCGA;ICGC;COSMIC	45.963	Down-regulation
CMGC_DYRK_DYRK2_DYRK2_ST	P04637	TP53	Q92630	DYRK2	T150	L145R	145	Missense	distal	-5	no	53.573	52.845	EPSD	TCGA;ICGC;COSMIC;GDSC;CCLE	45.963	Down-regulation
CMGC_DYRK_DYRK2_DYRK2_ST	P04637	TP53	Q92630	DYRK2	T150	T155I	155	Missense	distal	5	no	53.573	53.182	EPSD	TCGA;ICGC;COSMIC;CCLE	45.963	Down-regulation
CMGC_DYRK_DYRK2_DYRK2_ST	P04637	TP53	Q92630	DYRK2	T150	V143M	143	Missense	distal	-7	no	53.573	52.951	EPSD	TCGA;ICGC;COSMIC;GDSC;CCLE	45.963	Down-regulation
CMGC_DYRK_DYRK2_DYRK2_ST	P04637	TP53	Q92630	DYRK2	T150	T155N	155	Missense	distal	5	no	53.573	54.611	EPSD	TCGA;ICGC;COSMIC;GDSC;CCLE	45.963	Up-regulation
CMGC_DYRK_DYRK2_DYRK2_ST	P04637	TP53	Q92630	DYRK2	T150	P152S	152	Missense	proximal	2	no	53.573	53.060	EPSD	TCGA;ICGC;COSMIC;CCLE	45.963	Down-regulation
CMGC_DYRK_DYRK2_DYRK2_ST	P04637	TP53	Q92630	DYRK2	T150	R156C	156	Missense	distal	6	no	53.573	53.948	EPSD	TCGA;ICGC;COSMIC	45.963	Up-regulation
CMGC_DYRK_DYRK2_DYRK2_ST	P04637	TP53	Q92630	DYRK2	T150	P151T	151	Missense	proximal	1	no	53.573	31.498	EPSD	TCGA;ICGC;COSMIC	45.963	Loss
CMGC_DYRK_DYRK2_DYRK2_ST	P04637	TP53	Q92630	DYRK2	T150	T155P	155	Missense	distal	5	no	53.573	53.553	EPSD	TCGA;ICGC;COSMIC;CCLE	45.963	Down-regulation
CMGC_DYRK_DYRK2_DYRK2_ST	P04637	TP53	Q92630	DYRK2	T150	V143G	143	Missense	distal	-7	no	53.573	52.641	EPSD	TCGA;ICGC;COSMIC	45.963	Down-regulation
CMGC_DYRK_DYRK2_DYRK2_ST	P04637	TP53	Q92630	DYRK2	T150	P152Q	152	Missense	proximal	2	no	53.573	54.153	EPSD	TCGA;ICGC;COSMIC	45.963	Up-regulation
CMGC_DYRK_DYRK2_DYRK2_ST	P04637	TP53	Q92630	DYRK2	T150	R156H	156	Missense	distal	6	no	53.573	53.147	EPSD	TCGA;ICGC;COSMIC	45.963	Down-regulation
CMGC_DYRK_DYRK2_DYRK2_ST	P04637	TP53	Q92630	DYRK2	T150	L145P	145	Missense	distal	-5	no	53.573	52.334	EPSD	TCGA;ICGC;COSMIC	45.963	Down-regulation
CMGC_DYRK_DYRK2_DYRK2_ST	P04637	TP53	Q92630	DYRK2	T150	Q144L	144	Missense	distal	-6	no	53.573	54.057	EPSD	TCGA;ICGC;COSMIC	45.963	Up-regulation
CMGC_DYRK_DYRK2_DYRK2_ST	P04637	TP53	Q92630	DYRK2	T150	Q144H	144	Missense	distal	-6	no	53.573	54.173	EPSD	TCGA;ICGC;COSMIC	45.963	Up-regulation
CMGC_DYRK_DYRK2_DYRK2_ST	P04637	TP53	Q92630	DYRK2	T150	G154V	154	Missense	distal	4	no	53.573	53.701	EPSD	TCGA;ICGC;COSMIC;GDSC;CCLE	45.963	Up-regulation
CMGC_DYRK_DYRK2_DYRK2_ST	P04637	TP53	Q92630	DYRK2	T150	V157L	157	Missense	distal	7	no	53.573	50.599	EPSD	TCGA;ICGC;COSMIC	45.963	Down-regulation
CMGC_DYRK_DYRK2_DYRK2_ST	P04637	TP53	Q92630	DYRK2	T150	P151R	151	Missense	proximal	1	no	53.573	-2.816	EPSD	TCGA;ICGC;COSMIC	45.963	Loss
CMGC_DYRK_DYRK2_DYRK2_ST	P04637	TP53	Q92630	DYRK2	T150	Q144P	144	Missense	distal	-6	no	53.573	53.736	EPSD	TCGA;ICGC;COSMIC	45.963	Up-regulation
CMGC_DYRK_DYRK2_DYRK2_ST	P04637	TP53	Q92630	DYRK2	T150	V143E	143	Missense	distal	-7	no	53.573	51.259	EPSD	TCGA;ICGC;COSMIC	45.963	Down-regulation
CMGC_DYRK_DYRK2_DYRK2_ST	P04637	TP53	Q92630	DYRK2	T150	R156G	156	Missense	distal	6	no	53.573	53.391	EPSD	TCGA;ICGC;COSMIC	45.963	Down-regulation
CMGC_DYRK_DYRK2_DYRK2_ST	P04637	TP53	Q92630	DYRK2	T150	P151L	151	Missense	proximal	1	no	53.573	5.359	EPSD	TCGA;ICGC;COSMIC	45.963	Loss
CMGC_DYRK_DYRK2_DYRK2_ST	P04637	TP53	Q92630	DYRK2	T155	R156P	156	Missense	proximal	1	no	11.279	67.668	EPSD	TCGA;ICGC;COSMIC;GDSC;CCLE	45.963	Gain
CMGC_DYRK_DYRK2_DYRK2_ST	P04637	TP53	Q92630	DYRK2	T155	R156G	156	Missense	proximal	1	no	11.279	46.484	EPSD	TCGA;ICGC;COSMIC	45.963	Gain
CMGC_DYRK_DYRK2_DYRK2_ST	P04637	TP53	Q92630	DYRK2	S215	Y220C	220	Missense	distal	5	no	56.176	57.330	EPSD	TCGA;ICGC;COSMIC;GDSC;CCLE	45.963	Up-regulation
CMGC_DYRK_DYRK2_DYRK2_ST	P04637	TP53	Q92630	DYRK2	S215	R213Q	213	Missense	proximal	-2	no	56.176	48.470	EPSD	TCGA;ICGC;COSMIC;GDSC;CCLE	45.963	Down-regulation
CMGC_DYRK_DYRK2_DYRK2_ST	P04637	TP53	Q92630	DYRK2	S215	D208N	208	Missense	distal	-7	no	56.176	56.553	EPSD	TCGA;ICGC;COSMIC	45.963	Up-regulation
CMGC_DYRK_DYRK2_DYRK2_ST	P04637	TP53	Q92630	DYRK2	S215	H214R	214	Missense	proximal	-1	no	56.176	53.652	EPSD	TCGA;ICGC;COSMIC;GDSC;CCLE	45.963	Down-regulation
CMGC_DYRK_DYRK2_DYRK2_ST	P04637	TP53	Q92630	DYRK2	S215	V218E	218	Missense	distal	3	no	56.176	54.776	EPSD	TCGA;ICGC;COSMIC	45.963	Down-regulation
CMGC_DYRK_DYRK2_DYRK2_ST	P04637	TP53	Q92630	DYRK2	S215	Y220H	220	Missense	distal	5	no	56.176	54.641	EPSD	TCGA;ICGC;COSMIC	45.963	Down-regulation
CMGC_DYRK_DYRK2_DYRK2_ST	P04637	TP53	Q92630	DYRK2	S215	S215I	215	Missense	central	0	yes	56.176	0.000	EPSD	TCGA;ICGC;COSMIC;GDSC;CCLE	45.963	Loss
CMGC_DYRK_DYRK2_DYRK2_ST	P04637	TP53	Q92630	DYRK2	S215	V216M	216	Missense	proximal	1	no	56.176	34.334	EPSD	TCGA;ICGC;COSMIC;GDSC;CCLE	45.963	Loss
CMGC_DYRK_DYRK2_DYRK2_ST	P04637	TP53	Q92630	DYRK2	S215	Y220S	220	Missense	distal	5	no	56.176	55.554	EPSD	TCGA;ICGC;COSMIC	45.963	Down-regulation
CMGC_DYRK_DYRK2_DYRK2_ST	P04637	TP53	Q92630	DYRK2	S215	S215N	215	Missense	central	0	yes	56.176	0.000	EPSD	TCGA;ICGC;COSMIC;GDSC;CCLE	45.963	Loss
CMGC_DYRK_DYRK2_DYRK2_ST	P04637	TP53	Q92630	DYRK2	S215	T211I	211	Missense	distal	-4	no	56.176	57.083	EPSD	TCGA;ICGC;COSMIC;CCLE	45.963	Up-regulation
CMGC_DYRK_DYRK2_DYRK2_ST	P04637	TP53	Q92630	DYRK2	S215	V216G	216	Missense	proximal	1	no	56.176	43.023	EPSD	TCGA;ICGC;COSMIC	45.963	Loss
CMGC_DYRK_DYRK2_DYRK2_ST	P04637	TP53	Q92630	DYRK2	S215	R213L	213	Missense	proximal	-2	no	56.176	43.660	EPSD	TCGA;ICGC;COSMIC;GDSC;CCLE	45.963	Loss
CMGC_DYRK_DYRK2_DYRK2_ST	P04637	TP53	Q92630	DYRK2	S215	Y220D	220	Missense	distal	5	no	56.176	57.165	EPSD	TCGA;ICGC;COSMIC;GDSC;CCLE	45.963	Up-regulation
CMGC_DYRK_DYRK2_DYRK2_ST	P04637	TP53	Q92630	DYRK2	S215	V216E	216	Missense	proximal	1	no	56.176	-47.771	EPSD	TCGA;ICGC;COSMIC	45.963	Loss
CMGC_DYRK_DYRK2_DYRK2_ST	P04637	TP53	Q92630	DYRK2	S215	R209K	209	Missense	distal	-6	no	56.176	56.132	EPSD	TCGA;COSMIC	45.963	Down-regulation
CMGC_DYRK_DYRK2_DYRK2_ST	P04637	TP53	Q92630	DYRK2	S215	V218G	218	Missense	distal	3	no	56.176	56.162	EPSD	TCGA;ICGC;COSMIC	45.963	Down-regulation
CMGC_DYRK_DYRK2_DYRK2_ST	P04637	TP53	Q92630	DYRK2	S215	R213P	213	Missense	proximal	-2	no	56.176	50.723	EPSD	TCGA;ICGC;COSMIC	45.963	Down-regulation
CMGC_DYRK_DYRK2_DYRK2_ST	P04637	TP53	Q92630	DYRK2	S215	H214L	214	Missense	proximal	-1	no	56.176	54.949	EPSD	TCGA;ICGC;COSMIC	45.963	Down-regulation
CMGC_DYRK_DYRK2_DYRK2_ST	P04637	TP53	Q92630	DYRK2	S215	V216L	216	Missense	proximal	1	no	56.176	15.993	EPSD	TCGA;ICGC;COSMIC;GDSC;CCLE	45.963	Loss
CMGC_DYRK_DYRK2_DYRK2_ST	P04637	TP53	Q92630	DYRK2	S215	D208G	208	Missense	distal	-7	no	56.176	55.664	EPSD	TCGA;ICGC;COSMIC	45.963	Down-regulation
CMGC_DYRK_DYRK2_DYRK2_ST	P04637	TP53	Q92630	DYRK2	S215	S215G	215	Missense	central	0	yes	56.176	0.000	EPSD	TCGA;ICGC;COSMIC;GDSC;CCLE	45.963	Loss
CMGC_DYRK_DYRK2_DYRK2_ST	P04637	TP53	Q92630	DYRK2	S215	R209S	209	Missense	distal	-6	no	56.176	56.330	EPSD	TCGA;ICGC;COSMIC	45.963	Up-regulation
CMGC_DYRK_DYRK2_DYRK2_ST	P04637	TP53	Q92630	DYRK2	S215	R213G	213	Missense	proximal	-2	no	56.176	44.659	EPSD	TCGA;ICGC;COSMIC	45.963	Loss
CMGC_DYRK_DYRK2_DYRK2_ST	P04637	TP53	Q92630	DYRK2	S215	S215R	215	Missense	central	0	yes	56.176	0.000	EPSD	TCGA;ICGC;COSMIC;GDSC;CCLE	45.963	Loss
CMGC_DYRK_DYRK2_DYRK2_ST	P04637	TP53	Q92630	DYRK2	S215	R209I	209	Missense	distal	-6	no	56.176	56.358	EPSD	TCGA;ICGC;COSMIC	45.963	Up-regulation
CMGC_DYRK_DYRK2_DYRK2_ST	P04637	TP53	Q92630	DYRK2	S215	T211A	211	Missense	distal	-4	no	56.176	58.886	EPSD	TCGA;ICGC;COSMIC;CCLE	45.963	Up-regulation
CMGC_DYRK_DYRK2_DYRK2_ST	P04637	TP53	Q92630	DYRK2	T284	E285K	285	Missense	proximal	1	no	-29.043	66.739	EPSD	TCGA;ICGC;COSMIC;GDSC;CCLE	45.963	Gain
CMGC_DYRK_DYRK2_DYRK2_ST	P04637	TP53	Q92630	DYRK2	T284	E285V	285	Missense	proximal	1	no	-29.043	74.904	EPSD	TCGA;ICGC;COSMIC;GDSC;CCLE	45.963	Gain
CMGC_DYRK_DYRK2_DYRK2_ST	P04637	TP53	Q92630	DYRK2	S313	K319N	319	Missense	distal	6	no	47.453	47.468	EPSD	TCGA;ICGC;COSMIC	45.963	Up-regulation
CMGC_DYRK_DYRK2_DYRK2_ST	P04637	TP53	Q92630	DYRK2	S313	A307V	307	Missense	distal	-6	no	47.453	47.215	EPSD	TCGA;ICGC;COSMIC;GDSC	45.963	Down-regulation
CMGC_DYRK_DYRK2_DYRK2_ST	P04637	TP53	Q92630	DYRK2	S313	K320E	320	Missense	distal	7	no	47.453	43.157	EPSD	TCGA;ICGC;COSMIC	45.963	Loss
CMGC_DYRK_DYRK2_DYRK2_ST	P04637	TP53	Q92630	DYRK2	S313	S315C	315	Missense	proximal	2	no	47.453	48.947	EPSD	TCGA;ICGC;COSMIC	45.963	Up-regulation
CMGC_DYRK_DYRK2_DYRK2_ST	P04637	TP53	Q92630	DYRK2	S315	K319N	319	Missense	distal	4	no	59.350	59.409	EPSD	TCGA;ICGC;COSMIC	45.963	Up-regulation
CMGC_DYRK_DYRK2_DYRK2_ST	P04637	TP53	Q92630	DYRK2	S315	K320E	320	Missense	distal	5	no	59.350	60.329	EPSD	TCGA;ICGC;COSMIC	45.963	Up-regulation
CMGC_DYRK_DYRK2_DYRK2_ST	P04637	TP53	Q92630	DYRK2	S315	S315C	315	Missense	central	0	yes	59.350	0.000	EPSD	TCGA;ICGC;COSMIC	45.963	Loss
CMGC_DYRK_DYRK2_DYRK2_ST	Q14195	DPYSL3	Q92630	DYRK2	T509	P510S	510	Missense	proximal	1	no	56.305	26.904	EPSD	TCGA;COSMIC	45.963	Loss
CMGC_DYRK_DYRK2_DYRK2_ST	Q14195	DPYSL3	Q92630	DYRK2	T509	G513R	513	Missense	distal	4	no	56.305	56.441	EPSD	TCGA;COSMIC	45.963	Up-regulation
CMGC_DYRK_DYRK2_DYRK2_ST	Q14195	DPYSL3	Q92630	DYRK2	T514	P510S	510	Missense	distal	-4	no	52.124	53.391	EPSD	TCGA;COSMIC	45.963	Up-regulation
CMGC_DYRK_DYRK2_DYRK2_ST	Q14195	DPYSL3	Q92630	DYRK2	T514	G513R	513	Missense	proximal	-1	no	52.124	50.939	EPSD	TCGA;COSMIC	45.963	Down-regulation
CMGC_DYRK_DYRK2_DYRK2_ST	Q14195	DPYSL3	Q92630	DYRK2	S522	P528S	528	Missense	distal	6	no	87.074	86.802	PhosphoSitePlus	TCGA;COSMIC	45.963	Down-regulation
CMGC_DYRK_DYRK2_DYRK2_ST	Q16555	DPYSL2	Q92630	DYRK2	S304	F301V	301	Missense	distal	-3	no	55.536	60.886	EPSD	TCGA;COSMIC	45.963	Up-regulation
CMGC_DYRK_DYRK2_DYRK2_ST	Q16555	DPYSL2	Q92630	DYRK2	S308	F301V	301	Missense	distal	-7	no	47.734	49.884	EPSD	TCGA;COSMIC	45.963	Up-regulation
CMGC_DYRK_DYRK2_DYRK2_ST	Q16555	DPYSL2	Q92630	DYRK2	S363	N356Y	356	Missense	distal	-7	no	52.089	49.956	EPSD	TCGA;COSMIC	45.963	Down-regulation
CMGC_DYRK_DYRK2_DYRK2_ST	Q16555	DPYSL2	Q92630	DYRK2	S363	V364I	364	Missense	proximal	1	no	52.089	15.806	EPSD	TCGA;COSMIC	45.963	Loss
CMGC_DYRK_DYRK2_DYRK2_ST	Q16555	DPYSL2	Q92630	DYRK2	S416	A422T	422	Missense	distal	6	no	49.689	49.895	EPSD	TCGA	45.963	Up-regulation
CMGC_DYRK_DYRK2_DYRK2_ST	Q16555	DPYSL2	Q92630	DYRK2	S416	I411L	411	Missense	distal	-5	no	49.689	49.518	EPSD	TCGA;COSMIC	45.963	Down-regulation
CMGC_DYRK_DYRK2_DYRK2_ST	Q16555	DPYSL2	Q92630	DYRK2	S442	G436D	436	Missense	distal	-6	no	47.760	47.755	EPSD	TCGA	45.963	Down-regulation
CMGC_DYRK_DYRK2_DYRK2_ST	Q16555	DPYSL2	Q92630	DYRK2	S442	R440C	440	Missense	proximal	-2	no	47.760	44.496	EPSD	TCGA;COSMIC	45.963	Loss
CMGC_DYRK_DYRK2_DYRK2_ST	Q16555	DPYSL2	Q92630	DYRK2	S442	Q449K	449	Missense	distal	7	no	47.760	47.713	EPSD	TCGA;COSMIC	45.963	Down-regulation
CMGC_DYRK_DYRK2_DYRK2_ST	Q16555	DPYSL2	Q92630	DYRK2	T509	V513I	513	Missense	distal	4	no	56.167	56.066	EPSD	TCGA;COSMIC	45.963	Down-regulation
CMGC_DYRK_DYRK2_DYRK2_ST	Q16555	DPYSL2	Q92630	DYRK2	T509	T509M	509	Missense	central	0	yes	56.167	0.000	EPSD	TCGA;COSMIC	45.963	Loss
CMGC_DYRK_DYRK2_DYRK2_ST	Q16555	DPYSL2	Q92630	DYRK2	T509	P515S	515	Missense	distal	6	no	56.167	55.895	EPSD	TCGA;COSMIC	45.963	Down-regulation
CMGC_DYRK_DYRK2_DYRK2_ST	Q16555	DPYSL2	Q92630	DYRK2	T512	V513I	513	Missense	proximal	1	no	58.024	21.741	EPSD	TCGA;COSMIC	45.963	Loss
CMGC_DYRK_DYRK2_DYRK2_ST	Q16555	DPYSL2	Q92630	DYRK2	T512	T509M	509	Missense	distal	-3	no	58.024	60.731	EPSD	TCGA;COSMIC	45.963	Up-regulation
CMGC_DYRK_DYRK2_DYRK2_ST	Q16555	DPYSL2	Q92630	DYRK2	T512	P515S	515	Missense	distal	3	no	58.024	56.645	EPSD	TCGA;COSMIC	45.963	Down-regulation
CMGC_DYRK_DYRK2_DYRK2_ST	Q16555	DPYSL2	Q92630	DYRK2	T514	V513I	513	Missense	proximal	-1	no	61.228	61.518	EPSD	TCGA;COSMIC	45.963	Up-regulation
CMGC_DYRK_DYRK2_DYRK2_ST	Q16555	DPYSL2	Q92630	DYRK2	T514	T509M	509	Missense	distal	-5	no	61.228	61.771	EPSD	TCGA;COSMIC	45.963	Up-regulation
CMGC_DYRK_DYRK2_DYRK2_ST	Q16555	DPYSL2	Q92630	DYRK2	T514	P515S	515	Missense	proximal	1	no	61.228	31.827	EPSD	TCGA;COSMIC	45.963	Loss
CMGC_DYRK_DYRK2_DYRK2_ST	Q16555	DPYSL2	Q92630	DYRK2	T514	T521M	521	Missense	distal	7	no	61.228	60.115	EPSD	TCGA;COSMIC	45.963	Down-regulation
CMGC_DYRK_DYRK2_DYRK2_ST	Q16555	DPYSL2	Q92630	DYRK2	S522	P515S	515	Missense	distal	-7	no	81.328	80.105	PhosphoSitePlus	TCGA;COSMIC	45.963	Down-regulation
CMGC_DYRK_DYRK2_DYRK2_ST	Q16555	DPYSL2	Q92630	DYRK2	S522	T521M	521	Missense	proximal	-1	no	81.328	82.103	PhosphoSitePlus	TCGA;COSMIC	45.963	Up-regulation
CMGC_DYRK_DYRK2_DYRK2_ST	Q16555	DPYSL2	Q92630	DYRK2	S537	S537P	537	Missense	central	0	yes	47.827	0.000	EPSD	TCGA;COSMIC	45.963	Loss
CMGC_DYRK_DYRK2_DYRK2_ST	Q16555	DPYSL2	Q92630	DYRK2	T555	P561S	561	Missense	distal	6	no	49.385	49.114	EPSD	TCGA;COSMIC	45.963	Down-regulation
CMGC_DYRK_DYRK2_DYRK2_ST	Q16555	DPYSL2	Q92630	DYRK2	T555	R553H	553	Missense	proximal	-2	no	49.385	30.578	EPSD	TCGA;COSMIC	45.963	Loss
CMGC_DYRK_DYRK2_DYRK2_ST	Q16555	DPYSL2	Q92630	DYRK2	T569	R565H	565	Missense	distal	-4	no	66.385	58.951	EPSD	TCGA;COSMIC	45.963	Down-regulation
CMGC_DYRK_DYRK2_DYRK2_ST	P10636	MAPT	Q92630	DYRK2	S46	T52I	52	Missense	distal	6	no	55.663	55.311	EPSD	TCGA;ICGC;COSMIC	45.963	Down-regulation
CMGC_DYRK_DYRK2_DYRK2_ST	P10636	MAPT	Q92630	DYRK2	S46	P47S	47	Missense	proximal	1	no	55.663	26.262	EPSD	TCGA;ICGC;COSMIC	45.963	Loss
CMGC_DYRK_DYRK2_DYRK2_ST	P10636	MAPT	Q92630	DYRK2	S46	P47L	47	Missense	proximal	1	no	55.663	7.449	EPSD	TCGA;ICGC;COSMIC	45.963	Loss
CMGC_DYRK_DYRK2_DYRK2_ST	P10636	MAPT	Q92630	DYRK2	S46	G42C	42	Missense	distal	-4	no	55.663	66.825	EPSD	TCGA;ICGC;COSMIC	45.963	Up-regulation
CMGC_DYRK_DYRK2_DYRK2_ST	P10636	MAPT	Q92630	DYRK2	T50	D54E	54	Missense	distal	4	no	59.765	59.492	EPSD	TCGA;ICGC;COSMIC	45.963	Down-regulation
CMGC_DYRK_DYRK2_DYRK2_ST	P10636	MAPT	Q92630	DYRK2	T50	T52I	52	Missense	proximal	2	no	59.765	59.723	EPSD	TCGA;ICGC;COSMIC	45.963	Down-regulation
CMGC_DYRK_DYRK2_DYRK2_ST	P10636	MAPT	Q92630	DYRK2	T50	P47S	47	Missense	distal	-3	no	59.765	57.078	EPSD	TCGA;ICGC;COSMIC	45.963	Down-regulation
CMGC_DYRK_DYRK2_DYRK2_ST	P10636	MAPT	Q92630	DYRK2	T50	P47L	47	Missense	distal	-3	no	59.765	58.499	EPSD	TCGA;ICGC;COSMIC	45.963	Down-regulation
CMGC_DYRK_DYRK2_DYRK2_ST	P10636	MAPT	Q92630	DYRK2	T50	G55R	55	Missense	distal	5	no	59.765	63.057	EPSD	TCGA;ICGC;COSMIC	45.963	Up-regulation
CMGC_DYRK_DYRK2_DYRK2_ST	P10636	MAPT	Q92630	DYRK2	S68	A72V	72	Missense	distal	4	no	50.190	50.396	EPSD	TCGA;ICGC;COSMIC	45.963	Up-regulation
CMGC_DYRK_DYRK2_DYRK2_ST	P10636	MAPT	Q92630	DYRK2	S68	A66S	66	Missense	proximal	-2	no	50.190	52.346	EPSD	TCGA;ICGC;COSMIC	45.963	Up-regulation
CMGC_DYRK_DYRK2_DYRK2_ST	P10636	MAPT	Q92630	DYRK2	T69	A72V	72	Missense	distal	3	no	53.844	55.575	EPSD	TCGA;ICGC;COSMIC	45.963	Up-regulation
CMGC_DYRK_DYRK2_DYRK2_ST	P10636	MAPT	Q92630	DYRK2	T69	A66S	66	Missense	distal	-3	no	53.844	51.041	EPSD	TCGA;ICGC;COSMIC	45.963	Down-regulation
CMGC_DYRK_DYRK2_DYRK2_ST	P10636	MAPT	Q92630	DYRK2	T71	A72V	72	Missense	proximal	1	no	-4.680	59.782	EPSD	TCGA;ICGC;COSMIC	45.963	Gain
CMGC_DYRK_DYRK2_DYRK2_ST	P10636	MAPT	Q92630	DYRK2	S214	P212L	212	Missense	proximal	-2	no	65.937	58.874	EPSD	TCGA;ICGC;COSMIC	45.963	Down-regulation
CMGC_DYRK_DYRK2_DYRK2_ST	P10636	MAPT	Q92630	DYRK2	S214	E220K	220	Missense	distal	6	no	65.937	66.307	EPSD	TCGA;ICGC;COSMIC	45.963	Up-regulation
CMGC_DYRK_DYRK2_DYRK2_ST	P10636	MAPT	Q92630	DYRK2	S235	S232Y	232	Missense	distal	-3	no	48.540	52.159	EPSD	TCGA;ICGC;COSMIC	45.963	Up-regulation
CMGC_DYRK_DYRK2_DYRK2_ST	P10636	MAPT	Q92630	DYRK2	S235	A240T	240	Missense	distal	5	no	48.540	48.627	EPSD	TCGA;ICGC;COSMIC	45.963	Up-regulation
CMGC_DYRK_DYRK2_DYRK2_ST	P10636	MAPT	Q92630	DYRK2	S235	P234L	234	Missense	proximal	-1	no	48.540	50.280	EPSD	TCGA;ICGC;COSMIC	45.963	Up-regulation
CMGC_DYRK_DYRK2_DYRK2_ST	P10636	MAPT	Q92630	DYRK2	S238	S232Y	232	Missense	distal	-6	no	53.612	53.621	EPSD	TCGA;ICGC;COSMIC	45.963	Up-regulation
CMGC_DYRK_DYRK2_DYRK2_ST	P10636	MAPT	Q92630	DYRK2	S238	A240T	240	Missense	proximal	2	no	53.612	53.342	EPSD	TCGA;ICGC;COSMIC	45.963	Down-regulation
CMGC_DYRK_DYRK2_DYRK2_ST	P10636	MAPT	Q92630	DYRK2	S238	P234L	234	Missense	distal	-4	no	53.612	50.178	EPSD	TCGA;ICGC;COSMIC	45.963	Down-regulation
CMGC_DYRK_DYRK2_DYRK2_ST	P10636	MAPT	Q92630	DYRK2	S238	R244Q	244	Missense	distal	6	no	53.612	53.981	EPSD	TCGA;ICGC;COSMIC	45.963	Up-regulation
CMGC_DYRK_DYRK2_DYRK2_ST	P10636	MAPT	Q92630	DYRK2	S411	P415L	415	Missense	distal	4	no	70.167	69.953	EPSD	TCGA;ICGC;COSMIC	45.963	Down-regulation
CMGC_DYRK_DYRK2_DYRK2_ST	P10636	MAPT	Q92630	DYRK2	T416	P415L	415	Missense	proximal	-1	no	50.510	52.250	EPSD	TCGA;ICGC;COSMIC	45.963	Up-regulation
CMGC_DYRK_DYRK2_DYRK2_ST	P10636	MAPT	Q92630	DYRK2	S428	A430S	430	Missense	proximal	2	no	64.641	64.277	EPSD	TCGA;ICGC;COSMIC	45.963	Down-regulation
CMGC_DYRK_DYRK2_DYRK2_ST	P10636	MAPT	Q92630	DYRK2	S428	V431L	431	Missense	distal	3	no	64.641	64.020	EPSD	TCGA;ICGC;COSMIC	45.963	Down-regulation
CMGC_DYRK_DYRK2_DYRK2_ST	P10636	MAPT	Q92630	DYRK2	S428	A430V	430	Missense	proximal	2	no	64.641	64.523	EPSD	TCGA;ICGC;COSMIC	45.963	Down-regulation
CMGC_DYRK_DYRK2_DYRK2_ST	P10636	MAPT	Q92630	DYRK2	S438	P436T	436	Missense	proximal	-2	no	65.359	60.205	EPSD	TCGA;ICGC;COSMIC	45.963	Down-regulation
CMGC_DYRK_DYRK2_DYRK2_ST	P10636	MAPT	Q92630	DYRK2	S438	P436L	436	Missense	proximal	-2	no	65.359	58.297	EPSD	TCGA;ICGC;COSMIC	45.963	Down-regulation
CMGC_DYRK_DYRK2_DYRK2_ST	P10636	MAPT	Q92630	DYRK2	S438	K440E	440	Missense	proximal	2	no	65.359	65.100	EPSD	TCGA;ICGC;COSMIC	45.963	Down-regulation
CMGC_DYRK_DYRK2_DYRK2_ST	P10636	MAPT	Q92630	DYRK2	S438	S443F	443	Missense	distal	5	no	65.359	63.411	EPSD	TCGA;ICGC;COSMIC	45.963	Down-regulation
CMGC_DYRK_DYRK2_DYRK2_ST	P10636	MAPT	Q92630	DYRK2	S438	V431L	431	Missense	distal	-7	no	65.359	63.715	EPSD	TCGA;ICGC;COSMIC	45.963	Down-regulation
CMGC_DYRK_DYRK2_DYRK2_ST	P10636	MAPT	Q92630	DYRK2	S438	S444F	444	Missense	distal	6	no	65.359	65.040	EPSD	TCGA;ICGC	45.963	Down-regulation
CMGC_DYRK_DYRK2_DYRK2_ST	P10636	MAPT	Q92630	DYRK2	T470	R472Q	472	Missense	proximal	2	no	54.038	54.493	EPSD	TCGA	45.963	Up-regulation
CMGC_DYRK_DYRK2_DYRK2_ST	P10636	MAPT	Q92630	DYRK2	T470	R472W	472	Missense	proximal	2	no	54.038	53.563	EPSD	TCGA;COSMIC	45.963	Down-regulation
CMGC_DYRK_DYRK2_DYRK2_ST	P10636	MAPT	Q92630	DYRK2	T492	A485T	485	Missense	distal	-7	no	58.390	59.606	EPSD	TCGA;COSMIC;GDSC;CCLE	45.963	Up-regulation
CMGC_DYRK_DYRK2_DYRK2_ST	P10636	MAPT	Q92630	DYRK2	T492	P493Q	493	Missense	proximal	1	no	58.390	13.517	EPSD	TCGA;COSMIC	45.963	Loss
CMGC_DYRK_DYRK2_DYRK2_ST	P10636	MAPT	Q92630	DYRK2	T498	P493Q	493	Missense	distal	-5	no	56.812	57.184	EPSD	TCGA;COSMIC	45.963	Up-regulation
CMGC_DYRK_DYRK2_DYRK2_ST	P43686	PSMC4	Q92630	DYRK2	T25	G26D	26	Missense	proximal	1	no	64.572	53.086	PhosphoSitePlus	TCGA;ICGC;COSMIC	45.963	Down-regulation
CMGC_DYRK_DYRK2_DYRK2_ST	P43686	PSMC4	Q92630	DYRK2	T25	V20M	20	Missense	distal	-5	no	64.572	64.350	PhosphoSitePlus	TCGA;ICGC;COSMIC	45.963	Down-regulation
CMGC_DYRK_DYRK2_DYRK2_ST	Q9UHD2	TBK1	Q92630	DYRK2	S151	D157E	157	Missense	distal	6	no	46.876	46.787	EPSD	TCGA;ICGC;COSMIC	45.963	Down-regulation
CMGC_DYRK_DYRK2_DYRK2_ST	Q9UHD2	TBK1	Q92630	DYRK2	S151	F158C	158	Missense	distal	7	no	46.876	51.050	EPSD	TCGA;ICGC;COSMIC	45.963	Up-regulation
CMGC_DYRK_DYRK2_DYRK2_ST	Q9UHD2	TBK1	Q92630	DYRK2	T278	V275D	275	Missense	distal	-3	no	46.639	53.477	EPSD	TCGA;ICGC;COSMIC	45.963	Up-regulation
CMGC_DYRK_DYRK2_DYRK2_ST	Q9UHD2	TBK1	Q92630	DYRK2	T278	L281I	281	Missense	distal	3	no	46.639	46.880	EPSD	TCGA;ICGC;COSMIC	45.963	Up-regulation
CMGC_DYRK_DYRK2_DYRK2_ST	Q9UHD2	TBK1	Q92630	DYRK2	T278	L273I	273	Missense	distal	-5	no	46.639	46.810	EPSD	TCGA;ICGC	45.963	Up-regulation
CMGC_DYRK_DYRK2_DYRK2_ST	Q9UHD2	TBK1	Q92630	DYRK2	T278	R271Q	271	Missense	distal	-7	no	46.639	48.158	EPSD	TCGA;COSMIC	45.963	Up-regulation
CMGC_DYRK_DYRK2_DYRK2_ST	Q9UHD2	TBK1	Q92630	DYRK2	S527	A533V	533	Missense	distal	6	no	80.649	81.044	PhosphoSitePlus	TCGA;ICGC;COSMIC	45.963	Up-regulation
CMGC_DYRK_DYRK2_DYRK2_ST	Q9UHD2	TBK1	Q92630	DYRK2	S527	D523H	523	Missense	distal	-4	no	80.649	74.297	PhosphoSitePlus	TCGA;ICGC;COSMIC	45.963	Down-regulation
CMGC_DYRK_DYRK2_DYRK2_ST	Q9UHD2	TBK1	Q92630	DYRK2	T674	S680Y	680	Missense	distal	6	no	59.959	59.798	EPSD	TCGA;ICGC;COSMIC	45.963	Down-regulation
CMGC_DYRK_DYRK2_DYRK2_ST	Q14194	CRMP1	Q92630	DYRK2	T509	P510S	510	Missense	proximal	1	no	59.847	30.447	EPSD	TCGA	45.963	Loss
CMGC_DYRK_DYRK2_DYRK2_ST	Q14194	CRMP1	Q92630	DYRK2	T514	P510S	510	Missense	distal	-4	no	47.527	48.795	EPSD	TCGA	45.963	Up-regulation
CMGC_DYRK_DYRK2_DYRK2_ST	Q14194	CRMP1	Q92630	DYRK2	T554	G555D	555	Missense	proximal	1	no	48.580	37.094	EPSD	TCGA;COSMIC	45.963	Loss
CMGC_DYRK_DYRK2_DYRK2_ST	Q14194	CRMP1	Q92630	DYRK2	T554	V559A	559	Missense	distal	5	no	48.580	49.193	EPSD	TCGA;COSMIC	45.963	Up-regulation
CMGC_DYRK_DYRK2_DYRK2_ST	Q14194	CRMP1	Q92630	DYRK2	T569	G564C	564	Missense	distal	-5	no	55.373	54.301	EPSD	TCGA;COSMIC	45.963	Down-regulation
Other_BUB_BUB1_ST	O43684	BUB3	O43683	BUB1	S33	S33Y	33	Missense	central	0	yes	0.000	0.000	EPSD	TCGA;ICGC;COSMIC	0.000	Loss
Other_BUB_BUB1_ST	O43684	BUB3	O43683	BUB1	T154	T154P	154	Missense	central	0	yes	0.000	0.000	EPSD	TCGA;ICGC	0.000	Loss
Other_BUB_BUB1_ST	O43684	BUB3	O43683	BUB1	S211	S211R	211	Missense	central	0	yes	0.000	0.000	EPSD	TCGA;ICGC;COSMIC	0.000	Loss
Other_BUB_BUB1_ST	Q12834	CDC20	O43683	BUB1	S268	S268F	268	Missense	central	0	yes	0.000	0.000	EPSD	TCGA;ICGC;COSMIC	0.000	Loss
Other_BUB_BUB1_ST	Q12834	CDC20	O43683	BUB1	S268	S268P	268	Missense	central	0	yes	0.000	0.000	EPSD	TCGA;ICGC;COSMIC	0.000	Loss
Other_BUB_BUB1_ST	O43683	BUB1	O43683	BUB1	S176	S176L	176	Missense	central	0	yes	0.000	0.000	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	0.000	Loss
Other_BUB_BUB1_ST	O43683	BUB1	O43683	BUB1	S250	S250P	250	Missense	central	0	yes	0.000	0.000	EPSD	TCGA;ICGC;COSMIC	0.000	Loss
Other_BUB_BUB1_ST	O43683	BUB1	O43683	BUB1	T378	T378A	378	Missense	central	0	yes	0.000	0.000	EPSD	TCGA;COSMIC	0.000	Loss
Other_BUB_BUB1_ST	O43683	BUB1	O43683	BUB1	T412	T412A	412	Missense	central	0	yes	0.000	0.000	EPSD	TCGA;ICGC;COSMIC	0.000	Loss
Other_BUB_BUB1_ST	O43683	BUB1	O43683	BUB1	S437	S437Y	437	Missense	central	0	yes	0.000	0.000	EPSD	TCGA;ICGC;COSMIC	0.000	Loss
Other_BUB_BUB1_ST	O43683	BUB1	O43683	BUB1	T452	T452M	452	Missense	central	0	yes	0.000	0.000	EPSD	TCGA;ICGC;COSMIC;CCLE	0.000	Loss
Other_BUB_BUB1_ST	O43683	BUB1	O43683	BUB1	S459	S459P	459	Missense	central	0	yes	0.000	0.000	EPSD	TCGA;ICGC;COSMIC	0.000	Loss
Other_BUB_BUB1_ST	O43683	BUB1	O43683	BUB1	T552	T552I	552	Missense	central	0	yes	0.000	0.000	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	0.000	Loss
Other_BUB_BUB1_ST	O43683	BUB1	O43683	BUB1	S602	S602C	602	Missense	central	0	yes	0.000	0.000	EPSD	TCGA;ICGC;COSMIC	0.000	Loss
Other_BUB_BUB1_ST	O43683	BUB1	O43683	BUB1	S640	S640Y	640	Missense	central	0	yes	0.000	0.000	EPSD	TCGA;ICGC	0.000	Loss
Other_BUB_BUB1_ST	O43683	BUB1	O43683	BUB1	S667	S667L	667	Missense	central	0	yes	0.000	0.000	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC;GDSC;CCLE	0.000	Loss
Other_BUB_BUB1_ST	O43683	BUB1	O43683	BUB1	S752	S752F	752	Missense	central	0	yes	0.000	0.000	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	0.000	Loss
AGC_PKC_PKCh_PRKCE_ST	Q16625	OCLN	Q02156	PRKCE	S302	D307N	307	Missense	distal	5	no	14.168	14.109	EPSD	TCGA;ICGC;COSMIC	13.948	Down-regulation
AGC_PKC_PKCh_PRKCE_ST	Q16625	OCLN	Q02156	PRKCE	T403	G405D	405	Missense	proximal	2	no	15.391	14.934	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	13.948	Down-regulation
AGC_PKC_PKCh_PRKCE_ST	Q16625	OCLN	Q02156	PRKCE	T403	E407K	407	Missense	distal	4	no	15.391	16.970	EPSD;PhosphoSitePlus	TCGA;ICGC;GDSC;CCLE	13.948	Up-regulation
AGC_PKC_PKCh_PRKCE_ST	Q16625	OCLN	Q02156	PRKCE	T404	E407K	407	Missense	distal	3	no	13.879	14.506	PhosphoSitePlus;EPSD	TCGA;ICGC;GDSC;CCLE	13.948	Gain
AGC_PKC_PKCh_PRKCE_ST	O14649	KCNK3	Q02156	PRKCE	T383	S380N	380	Missense	distal	-3	no	20.307	17.719	PhosphoSitePlus	TCGA;ICGC	13.948	Down-regulation
AGC_PKC_PKCh_PRKCE_ST	P10636	MAPT	Q02156	PRKCE	S64	A66S	66	Missense	proximal	2	no	13.304	14.035	EPSD	TCGA;ICGC;COSMIC	13.948	Gain
AGC_PKC_PKCh_PRKCE_ST	P10636	MAPT	Q02156	PRKCE	T167	R168H	168	Missense	proximal	1	no	14.232	11.681	EPSD	TCGA;ICGC;COSMIC	13.948	Loss
AGC_PKC_PKCh_PRKCE_ST	P10636	MAPT	Q02156	PRKCE	T167	R168C	168	Missense	proximal	1	no	14.232	12.646	EPSD	TCGA;ICGC;COSMIC	13.948	Loss
AGC_PKC_PKCh_PRKCE_ST	P10636	MAPT	Q02156	PRKCE	S214	P212L	212	Missense	proximal	-2	no	15.548	13.116	EPSD	TCGA;ICGC;COSMIC	13.948	Loss
AGC_PKC_PKCh_PRKCE_ST	P10636	MAPT	Q02156	PRKCE	S214	E220K	220	Missense	distal	6	no	15.548	15.843	EPSD	TCGA;ICGC;COSMIC	13.948	Up-regulation
AGC_PKC_PKCh_PRKCE_ST	P10636	MAPT	Q02156	PRKCE	S341	E348V	348	Missense	distal	7	no	20.741	20.011	EPSD	TCGA;ICGC;COSMIC	13.948	Down-regulation
AGC_PKC_PKCh_PRKCE_ST	P10636	MAPT	Q02156	PRKCE	S341	G339R	339	Missense	proximal	-2	no	20.741	21.331	EPSD	TCGA;ICGC;COSMIC	13.948	Up-regulation
AGC_PKC_PKCh_PRKCE_ST	P10636	MAPT	Q02156	PRKCE	S341	S341F	341	Missense	central	0	yes	20.741	0.000	EPSD	TCGA;ICGC;COSMIC	13.948	Loss
AGC_PKC_PKCh_PRKCE_ST	P10636	MAPT	Q02156	PRKCE	S355	E348V	348	Missense	distal	-7	no	15.706	15.441	EPSD	TCGA;ICGC;COSMIC	13.948	Down-regulation
AGC_PKC_PKCh_PRKCE_ST	P10636	MAPT	Q02156	PRKCE	S355	D350G	350	Missense	distal	-5	no	15.706	15.689	EPSD	TCGA;ICGC;COSMIC	13.948	Down-regulation
AGC_PKC_PKCh_PRKCE_ST	P10636	MAPT	Q02156	PRKCE	S369	Q373R	373	Missense	distal	4	no	15.708	16.239	EPSD	TCGA;ICGC;COSMIC	13.948	Up-regulation
AGC_PKC_PKCh_PRKCE_ST	P10636	MAPT	Q02156	PRKCE	S369	K366E	366	Missense	distal	-3	no	15.708	8.582	EPSD	TCGA;ICGC;COSMIC	13.948	Loss
AGC_PKC_PKCh_PRKCE_ST	P10636	MAPT	Q02156	PRKCE	S438	P436T	436	Missense	proximal	-2	no	14.553	12.904	EPSD	TCGA;ICGC;COSMIC	13.948	Loss
AGC_PKC_PKCh_PRKCE_ST	P10636	MAPT	Q02156	PRKCE	S438	P436L	436	Missense	proximal	-2	no	14.553	12.121	EPSD	TCGA;ICGC;COSMIC	13.948	Loss
AGC_PKC_PKCh_PRKCE_ST	P10636	MAPT	Q02156	PRKCE	S438	K440E	440	Missense	proximal	2	no	14.553	7.886	EPSD	TCGA;ICGC;COSMIC	13.948	Loss
AGC_PKC_PKCh_PRKCE_ST	P10636	MAPT	Q02156	PRKCE	S438	S443F	443	Missense	distal	5	no	14.553	14.643	EPSD	TCGA;ICGC;COSMIC	13.948	Up-regulation
AGC_PKC_PKCh_PRKCE_ST	P10636	MAPT	Q02156	PRKCE	S438	V431L	431	Missense	distal	-7	no	14.553	14.614	EPSD	TCGA;ICGC;COSMIC	13.948	Up-regulation
AGC_PKC_PKCh_PRKCE_ST	P10636	MAPT	Q02156	PRKCE	S438	S444F	444	Missense	distal	6	no	14.553	14.586	EPSD	TCGA;ICGC	13.948	Up-regulation
AGC_PKC_PKCh_PRKCE_ST	P10636	MAPT	Q02156	PRKCE	S451	E456K	456	Missense	distal	5	no	19.978	19.998	EPSD	TCGA;ICGC;COSMIC	13.948	Up-regulation
AGC_PKC_PKCh_PRKCE_ST	P10636	MAPT	Q02156	PRKCE	S451	S452C	452	Missense	proximal	1	no	19.978	18.811	EPSD	TCGA;ICGC;COSMIC	13.948	Down-regulation
AGC_PKC_PKCh_PRKCE_ST	P10636	MAPT	Q02156	PRKCE	S451	S444F	444	Missense	distal	-7	no	19.978	19.700	EPSD	TCGA;ICGC	13.948	Down-regulation
AGC_PKC_PKCh_PRKCE_ST	P10636	MAPT	Q02156	PRKCE	S451	S452Y	452	Missense	proximal	1	no	19.978	21.996	EPSD	TCGA;ICGC;COSMIC	13.948	Up-regulation
AGC_PKC_PKCh_PRKCE_ST	O75689	ADAP1	Q02156	PRKCE	S204	D202N	202	Missense	proximal	-2	no	18.789	19.664	EPSD	TCGA;ICGC;COSMIC	13.948	Up-regulation
AGC_PKC_PKCh_PRKCE_ST	O75689	ADAP1	Q02156	PRKCE	S204	N203S	203	Missense	proximal	-1	no	18.789	18.913	EPSD	TCGA;COSMIC	13.948	Up-regulation
AGC_PKC_PKCh_PRKCE_ST	O75689	ADAP1	Q02156	PRKCE	T276	D278N	278	Missense	proximal	2	no	15.841	15.436	PhosphoSitePlus;EPSD	TCGA;COSMIC	13.948	Down-regulation
AGC_PKC_PKCh_PRKCE_ST	O75689	ADAP1	Q02156	PRKCE	T276	R271W	271	Missense	distal	-5	no	15.841	15.909	PhosphoSitePlus;EPSD	TCGA;COSMIC	13.948	Up-regulation
AGC_PKC_PKCh_PRKCE_ST	Q9H9S0	NANOG	Q02156	PRKCE	S71	T78I	78	Missense	distal	7	no	16.922	16.674	EPSD	TCGA;ICGC;COSMIC	13.948	Down-regulation
AGC_PKC_PKCh_PRKCE_ST	Q9H9S0	NANOG	Q02156	PRKCE	S71	S68Y	68	Missense	distal	-3	no	16.922	15.874	EPSD	TCGA;ICGC;COSMIC	13.948	Down-regulation
AGC_PKC_PKCh_PRKCE_ST	Q9H9S0	NANOG	Q02156	PRKCE	T78	A80V	80	Missense	proximal	2	no	17.942	20.360	PhosphoSitePlus;EPSD	TCGA;ICGC;COSMIC	13.948	Up-regulation
AGC_PKC_PKCh_PRKCE_ST	Q9H9S0	NANOG	Q02156	PRKCE	T78	T78I	78	Missense	central	0	yes	17.942	0.000	PhosphoSitePlus;EPSD	TCGA;ICGC;COSMIC	13.948	Loss
AGC_PKC_PKCh_PRKCE_ST	Q9H9S0	NANOG	Q02156	PRKCE	T78	E81D	81	Missense	distal	3	no	17.942	18.364	PhosphoSitePlus;EPSD	TCGA;ICGC;COSMIC	13.948	Up-regulation
AGC_PKC_PKCh_PRKCE_ST	Q9H9S0	NANOG	Q02156	PRKCE	T78	A85T	85	Missense	distal	7	no	17.942	17.104	PhosphoSitePlus;EPSD	TCGA;ICGC;COSMIC	13.948	Down-regulation
AGC_PKC_PKCh_PRKCE_ST	Q9H9S0	NANOG	Q02156	PRKCE	S79	A80V	80	Missense	proximal	1	no	16.737	17.158	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	13.948	Up-regulation
AGC_PKC_PKCh_PRKCE_ST	Q9H9S0	NANOG	Q02156	PRKCE	S79	T78I	78	Missense	proximal	-1	no	16.737	16.488	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	13.948	Down-regulation
AGC_PKC_PKCh_PRKCE_ST	Q9H9S0	NANOG	Q02156	PRKCE	S79	E81D	81	Missense	proximal	2	no	16.737	17.352	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	13.948	Up-regulation
AGC_PKC_PKCh_PRKCE_ST	Q9H9S0	NANOG	Q02156	PRKCE	S79	A85T	85	Missense	distal	6	no	16.737	16.984	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	13.948	Up-regulation
AGC_PKC_PKCh_PRKCE_ST	Q9H9S0	NANOG	Q02156	PRKCE	S135	L134F	134	Missense	proximal	-1	no	17.661	18.032	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	13.948	Up-regulation
AGC_PKC_PKCh_PRKCE_ST	Q9H9S0	NANOG	Q02156	PRKCE	T200	P194S	194	Missense	distal	-6	no	15.548	15.559	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	13.948	Up-regulation
AGC_PKC_PKCh_PRKCE_ST	Q9H9S0	NANOG	Q02156	PRKCE	S258	Q255K	255	Missense	distal	-3	no	8.552	14.136	EPSD	TCGA;ICGC;COSMIC	13.948	Gain
AGC_PKC_PKCh_PRKCE_ST	Q9H9S0	NANOG	Q02156	PRKCE	T289	M290L	290	Missense	proximal	1	no	19.380	19.425	EPSD	TCGA;ICGC;COSMIC	13.948	Up-regulation
AGC_PKC_PKCh_PRKCE_ST	Q9H9S0	NANOG	Q02156	PRKCE	T289	L294I	294	Missense	distal	5	no	19.380	19.588	EPSD	TCGA;ICGC	13.948	Up-regulation
AGC_PKC_PKCh_PRKCE_ST	Q14145	KEAP1	Q02156	PRKCE	S599	T598A	598	Missense	proximal	-1	no	31.933	32.125	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	13.948	Up-regulation
AGC_PKC_PKCh_PRKCE_ST	Q14145	KEAP1	Q02156	PRKCE	S599	S592G	592	Missense	distal	-7	no	31.933	31.886	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	13.948	Down-regulation
AGC_PKC_PKCh_PRKCE_ST	Q14145	KEAP1	Q02156	PRKCE	S599	G603W	603	Missense	distal	4	no	31.933	27.177	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	13.948	Down-regulation
AGC_PKC_PKCh_PRKCE_ST	Q14145	KEAP1	Q02156	PRKCE	S599	R601L	601	Missense	proximal	2	no	31.933	24.297	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	13.948	Down-regulation
AGC_PKC_PKCh_PRKCE_ST	Q14145	KEAP1	Q02156	PRKCE	S602	T598A	598	Missense	distal	-4	no	19.003	19.102	PhosphoSitePlus;EPSD	TCGA;ICGC;COSMIC	13.948	Up-regulation
AGC_PKC_PKCh_PRKCE_ST	Q14145	KEAP1	Q02156	PRKCE	S602	A607P	607	Missense	distal	5	no	19.003	18.851	PhosphoSitePlus;EPSD	TCGA;ICGC;COSMIC	13.948	Down-regulation
AGC_PKC_PKCh_PRKCE_ST	Q14145	KEAP1	Q02156	PRKCE	S602	G603W	603	Missense	proximal	1	no	19.003	17.094	PhosphoSitePlus;EPSD	TCGA;ICGC;COSMIC	13.948	Down-regulation
AGC_PKC_PKCh_PRKCE_ST	Q14145	KEAP1	Q02156	PRKCE	S602	R601L	601	Missense	proximal	-1	no	19.003	18.259	PhosphoSitePlus;EPSD	TCGA;ICGC;COSMIC	13.948	Down-regulation
AGC_PKC_PKCh_PRKCE_ST	Q92934	BAD	Q02156	PRKCE	S75	S71I	71	Missense	distal	-4	no	18.907	18.955	PhosphoSitePlus;EPSD	TCGA;ICGC;COSMIC	13.948	Up-regulation
AGC_PKC_PKCh_PRKCE_ST	Q92934	BAD	Q02156	PRKCE	S97	A100T	100	Missense	distal	3	no	17.410	17.007	EPSD	TCGA;ICGC;COSMIC	13.948	Down-regulation
AGC_PKC_PKCh_PRKCE_ST	Q92934	BAD	Q02156	PRKCE	S99	A100T	100	Missense	proximal	1	no	15.361	15.515	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	13.948	Up-regulation
AGC_PKC_PKCh_PRKCE_ST	Q92934	BAD	Q02156	PRKCE	S118	M117I	117	Missense	proximal	-1	no	16.614	15.046	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	13.948	Down-regulation
AGC_PKC_PKCh_PRKCE_ST	Q92934	BAD	Q02156	PRKCE	S124	M117I	117	Missense	distal	-7	no	21.399	20.909	EPSD	TCGA;ICGC;COSMIC	13.948	Down-regulation
AGC_PKC_PKCh_PRKCE_ST	Q92934	BAD	Q02156	PRKCE	S124	R131H	131	Missense	distal	7	no	21.399	20.570	EPSD	TCGA;ICGC;COSMIC	13.948	Down-regulation
AGC_PKC_PKCh_PRKCE_ST	Q92934	BAD	Q02156	PRKCE	S163	G162V	162	Missense	proximal	-1	no	17.205	16.600	EPSD	TCGA;ICGC;COSMIC	13.948	Down-regulation
AGC_PKC_PKCh_PRKCE_ST	Q92934	BAD	Q02156	PRKCE	S163	S164F	164	Missense	proximal	1	no	17.205	18.541	EPSD	TCGA;ICGC;COSMIC;GDSC;CCLE	13.948	Up-regulation
AGC_PKC_PKCh_PRKCE_ST	Q92934	BAD	Q02156	PRKCE	S163	S167P	167	Missense	distal	4	no	17.205	17.079	EPSD	TCGA;COSMIC	13.948	Down-regulation
AGC_PKC_PKCh_PRKCE_ST	Q92934	BAD	Q02156	PRKCE	S163	S163N	163	Missense	central	0	yes	17.205	0.000	EPSD	TCGA;ICGC;COSMIC	13.948	Loss
AGC_PKC_PKCh_PRKCE_ST	Q92934	BAD	Q02156	PRKCE	S163	G162E	162	Missense	proximal	-1	no	17.205	17.215	EPSD	TCGA;ICGC	13.948	Up-regulation
AGC_PKC_PKCh_PRKCE_ST	Q92934	BAD	Q02156	PRKCE	S164	G162V	162	Missense	proximal	-2	no	24.444	23.471	EPSD	TCGA;ICGC;COSMIC	13.948	Down-regulation
AGC_PKC_PKCh_PRKCE_ST	Q92934	BAD	Q02156	PRKCE	S164	S164F	164	Missense	central	0	yes	24.444	0.000	EPSD	TCGA;ICGC;COSMIC;GDSC;CCLE	13.948	Loss
AGC_PKC_PKCh_PRKCE_ST	Q92934	BAD	Q02156	PRKCE	S164	S167P	167	Missense	distal	3	no	24.444	24.504	EPSD	TCGA;COSMIC	13.948	Up-regulation
AGC_PKC_PKCh_PRKCE_ST	Q92934	BAD	Q02156	PRKCE	S164	S163N	163	Missense	proximal	-1	no	24.444	24.320	EPSD	TCGA;ICGC;COSMIC	13.948	Down-regulation
AGC_PKC_PKCh_PRKCE_ST	Q92934	BAD	Q02156	PRKCE	S164	G162E	162	Missense	proximal	-2	no	24.444	23.544	EPSD	TCGA;ICGC	13.948	Down-regulation
AGC_PKC_PKCh_PRKCE_ST	P78536	ADAM17	Q02156	PRKCE	T87	F94L	94	Missense	distal	7	no	15.090	14.293	EPSD	TCGA;ICGC;COSMIC	13.948	Down-regulation
AGC_PKC_PKCh_PRKCE_ST	P78536	ADAM17	Q02156	PRKCE	T87	T84P	84	Missense	distal	-3	no	15.090	11.579	EPSD	TCGA;ICGC;COSMIC	13.948	Loss
AGC_PKC_PKCh_PRKCE_ST	P78536	ADAM17	Q02156	PRKCE	T87	K80E	80	Missense	distal	-7	no	15.090	15.193	EPSD	TCGA;ICGC	13.948	Up-regulation
AGC_PKC_PKCh_PRKCE_ST	P78536	ADAM17	Q02156	PRKCE	S180	P181L	181	Missense	proximal	1	no	16.203	17.566	EPSD	TCGA;ICGC;COSMIC	13.948	Up-regulation
AGC_PKC_PKCh_PRKCE_ST	P78536	ADAM17	Q02156	PRKCE	S180	S176L	176	Missense	distal	-4	no	16.203	16.117	EPSD	TCGA;ICGC;COSMIC	13.948	Down-regulation
AGC_PKC_PKCh_PRKCE_ST	P78536	ADAM17	Q02156	PRKCE	S180	R177C	177	Missense	distal	-3	no	16.203	8.113	EPSD	TCGA;ICGC;COSMIC	13.948	Loss
AGC_PKC_PKCh_PRKCE_ST	P78536	ADAM17	Q02156	PRKCE	S360	G363A	363	Missense	distal	3	no	16.902	16.560	EPSD	TCGA;ICGC;COSMIC	13.948	Down-regulation
AGC_PKC_PKCh_PRKCE_ST	P78536	ADAM17	Q02156	PRKCE	S717	E714K	714	Missense	distal	-3	no	7.029	14.155	EPSD	TCGA;ICGC	13.948	Gain
AGC_PKC_PKCh_PRKCE_ST	P78536	ADAM17	Q02156	PRKCE	S723	R725H	725	Missense	proximal	2	no	15.951	8.980	EPSD	TCGA;ICGC;COSMIC	13.948	Loss
AGC_PKC_PKCh_PRKCE_ST	P78536	ADAM17	Q02156	PRKCE	S723	M719I	719	Missense	distal	-4	no	15.951	16.076	EPSD	TCGA;ICGC;COSMIC	13.948	Up-regulation
AGC_PKC_PKCh_PRKCE_ST	P78536	ADAM17	Q02156	PRKCE	S723	S723L	723	Missense	central	0	yes	15.951	0.000	EPSD	TCGA;ICGC;COSMIC	13.948	Loss
AGC_PKC_PKCh_PRKCE_ST	P78536	ADAM17	Q02156	PRKCE	S808	R813C	813	Missense	distal	5	no	33.589	33.878	EPSD	TCGA;ICGC;COSMIC	13.948	Up-regulation
AGC_PKC_PKCh_PRKCE_ST	P78536	ADAM17	Q02156	PRKCE	S808	R802K	802	Missense	distal	-6	no	33.589	33.549	EPSD	TCGA;ICGC;COSMIC	13.948	Down-regulation
AGC_PKC_PKCh_PRKCE_ST	P78536	ADAM17	Q02156	PRKCE	S808	A806V	806	Missense	proximal	-2	no	33.589	33.753	EPSD	TCGA;ICGC;COSMIC	13.948	Up-regulation
AGC_PKC_PKCh_PRKCE_ST	P78536	ADAM17	Q02156	PRKCE	S819	R813C	813	Missense	distal	-6	no	20.230	20.122	EPSD	TCGA;ICGC;COSMIC	13.948	Down-regulation
AGC_PKC_PKCh_PRKCE_ST	P04899	GNAI2	Q02156	PRKCE	S44	L37M	37	Missense	distal	-7	no	21.352	21.812	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	13.948	Up-regulation
AGC_PKC_PKCh_PRKCE_ST	P04899	GNAI2	Q02156	PRKCE	S207	G204D	204	Missense	distal	-3	no	13.881	14.750	EPSD	TCGA;COSMIC	13.948	Gain
AGC_PKC_PKCh_PRKCE_ST	P04899	GNAI2	Q02156	PRKCE	S302	Y297H	297	Missense	distal	-5	no	16.150	16.166	EPSD;PhosphoSitePlus	TCGA;COSMIC	13.948	Up-regulation
AGC_PKC_PKCh_PRKCE_ST	P16220	CREB1	Q02156	PRKCE	S133	L128I	128	Missense	distal	-5	no	22.554	22.578	PhosphoSitePlus	TCGA;COSMIC	13.948	Up-regulation
AGC_PKC_PKCh_PRKCE_ST	P43629	KIR3DL1	Q02156	PRKCE	T118	P124T	124	Missense	distal	6	no	15.832	15.784	EPSD	TCGA;ICGC;COSMIC	13.948	Down-regulation
AGC_PKC_PKCh_PRKCE_ST	P43629	KIR3DL1	Q02156	PRKCE	T118	P124H	124	Missense	distal	6	no	15.832	15.993	EPSD	TCGA;ICGC;COSMIC	13.948	Up-regulation
AGC_PKC_PKCh_PRKCE_ST	P43629	KIR3DL1	Q02156	PRKCE	T118	G119E	119	Missense	proximal	1	no	15.832	13.937	EPSD	TCGA;ICGC;COSMIC	13.948	Loss
AGC_PKC_PKCh_PRKCE_ST	P43629	KIR3DL1	Q02156	PRKCE	T118	S125F	125	Missense	distal	7	no	15.832	16.172	EPSD	TCGA;ICGC;COSMIC	13.948	Up-regulation
AGC_PKC_PKCh_PRKCE_ST	P43629	KIR3DL1	Q02156	PRKCE	T118	T118P	118	Missense	central	0	yes	15.832	0.000	EPSD	TCGA;ICGC;COSMIC	13.948	Loss
AGC_PKC_PKCh_PRKCE_ST	P43629	KIR3DL1	Q02156	PRKCE	S296	F294S	294	Missense	proximal	-2	no	12.344	14.209	EPSD	TCGA;ICGC	13.948	Gain
AGC_PKC_PKCh_PRKCE_ST	P43629	KIR3DL1	Q02156	PRKCE	S388	E390K	390	Missense	proximal	2	no	9.802	16.469	EPSD	TCGA;COSMIC	13.948	Gain
AGC_PKC_PKCh_PRKCE_ST	P43629	KIR3DL1	Q02156	PRKCE	S415	R413C	413	Missense	proximal	-2	no	17.613	16.109	PhosphoSitePlus	TCGA;ICGC;COSMIC	13.948	Down-regulation
AGC_PKC_PKCh_PRKCE_ST	P43629	KIR3DL1	Q02156	PRKCE	S415	P421H	421	Missense	distal	6	no	17.613	17.774	PhosphoSitePlus	TCGA;COSMIC	13.948	Up-regulation
AGC_PKC_PKCh_PRKCE_ST	P43629	KIR3DL1	Q02156	PRKCE	S415	Q408K	408	Missense	distal	-7	no	17.613	17.574	PhosphoSitePlus	TCGA;COSMIC	13.948	Down-regulation
AGC_PKC_PKCh_PRKCE_ST	P43629	KIR3DL1	Q02156	PRKCE	S415	R413H	413	Missense	proximal	-2	no	17.613	15.063	PhosphoSitePlus	TCGA;COSMIC	13.948	Down-regulation
AGC_PKC_PKCh_PRKCE_ST	P43629	KIR3DL1	Q02156	PRKCE	S415	T412S	412	Missense	distal	-3	no	17.613	17.419	PhosphoSitePlus	TCGA;COSMIC	13.948	Down-regulation
AGC_PKC_PKCh_PRKCE_ST	P43629	KIR3DL1	Q02156	PRKCE	S415	P418H	418	Missense	distal	3	no	17.613	16.887	PhosphoSitePlus	TCGA;COSMIC	13.948	Down-regulation
AGC_PKC_PKCh_PRKCE_ST	P43629	KIR3DL1	Q02156	PRKCE	T420	R413C	413	Missense	distal	-7	no	14.228	14.123	EPSD	TCGA;ICGC;COSMIC	13.948	Down-regulation
AGC_PKC_PKCh_PRKCE_ST	P43629	KIR3DL1	Q02156	PRKCE	T420	P421H	421	Missense	proximal	1	no	14.228	13.225	EPSD	TCGA;COSMIC	13.948	Loss
AGC_PKC_PKCh_PRKCE_ST	P43629	KIR3DL1	Q02156	PRKCE	T420	D424E	424	Missense	distal	4	no	14.228	13.582	EPSD	TCGA;COSMIC	13.948	Loss
AGC_PKC_PKCh_PRKCE_ST	P43629	KIR3DL1	Q02156	PRKCE	T420	I426F	426	Missense	distal	6	no	14.228	14.193	EPSD	TCGA;COSMIC	13.948	Down-regulation
AGC_PKC_PKCh_PRKCE_ST	P43629	KIR3DL1	Q02156	PRKCE	T420	R413H	413	Missense	distal	-7	no	14.228	13.763	EPSD	TCGA;COSMIC	13.948	Loss
AGC_PKC_PKCh_PRKCE_ST	P43629	KIR3DL1	Q02156	PRKCE	T420	P418H	418	Missense	proximal	-2	no	14.228	12.349	EPSD	TCGA;COSMIC	13.948	Loss
AGC_PKC_PKCh_PRKCE_ST	P43629	KIR3DL1	Q02156	PRKCE	S442	P436L	436	Missense	distal	-6	no	15.499	15.479	EPSD	TCGA;COSMIC	13.948	Down-regulation
AGC_PKC_PKCh_PRKCE_ST	P43629	KIR3DL1	Q02156	PRKCE	S442	S442F	442	Missense	central	0	yes	15.499	0.000	EPSD	TCGA;COSMIC	13.948	Loss
AGC_PKC_PKCh_PRKCE_ST	Q9UBS0	RPS6KB2	Q02156	PRKCE	S410	S410L	410	Missense	central	0	yes	17.760	0.000	EPSD	TCGA;ICGC;COSMIC	13.948	Loss
AGC_PKC_PKCh_PRKCE_ST	Q9UBS0	RPS6KB2	Q02156	PRKCE	S416	R419W	419	Missense	distal	3	no	15.168	14.363	EPSD	TCGA;ICGC;COSMIC	13.948	Down-regulation
AGC_PKC_PKCh_PRKCE_ST	Q9UBS0	RPS6KB2	Q02156	PRKCE	S416	S410L	410	Missense	distal	-6	no	15.168	15.137	EPSD	TCGA;ICGC;COSMIC	13.948	Down-regulation
AGC_PKC_PKCh_PRKCE_ST	P05783	KRT18	Q02156	PRKCE	S53	G57D	57	Missense	distal	4	no	23.709	22.296	PhosphoSitePlus	TCGA;ICGC;COSMIC	13.948	Down-regulation
AGC_PKC_PKCh_PRKCE_ST	P05783	KRT18	Q02156	PRKCE	S53	S60Y	60	Missense	distal	7	no	23.709	24.418	PhosphoSitePlus	TCGA;ICGC;COSMIC	13.948	Up-regulation
AGC_PKC_PKCh_PRKCE_ST	P05783	KRT18	Q02156	PRKCE	T409	R411H	411	Missense	proximal	2	no	18.334	11.362	EPSD	TCGA;ICGC;COSMIC	13.948	Loss
AGC_PKC_PKCh_PRKCE_ST	P05783	KRT18	Q02156	PRKCE	T409	R412Q	412	Missense	distal	3	no	18.334	18.168	EPSD	TCGA;ICGC;COSMIC	13.948	Down-regulation
AGC_PKC_PKCh_PRKCE_ST	P05783	KRT18	Q02156	PRKCE	S420	E421Q	421	Missense	proximal	1	no	16.023	16.485	EPSD	TCGA;ICGC;COSMIC	13.948	Up-regulation
AGC_PKC_PKCh_PRKCE_ST	P05783	KRT18	Q02156	PRKCE	S420	D424Y	424	Missense	distal	4	no	16.023	14.999	EPSD	TCGA;ICGC;COSMIC;CCLE	13.948	Down-regulation
AGC_PKC_PKCh_PRKCE_ST	P05783	KRT18	Q02156	PRKCE	T422	E421Q	421	Missense	proximal	-1	no	15.978	15.834	EPSD	TCGA;ICGC;COSMIC	13.948	Down-regulation
AGC_PKC_PKCh_PRKCE_ST	P05783	KRT18	Q02156	PRKCE	T422	D424Y	424	Missense	proximal	2	no	15.978	14.665	EPSD	TCGA;ICGC;COSMIC;CCLE	13.948	Down-regulation
AGC_PKC_PKCh_PRKCE_ST	P05783	KRT18	Q02156	PRKCE	T425	E421Q	421	Missense	distal	-4	no	15.867	15.893	EPSD	TCGA;ICGC;COSMIC	13.948	Up-regulation
AGC_PKC_PKCh_PRKCE_ST	P05783	KRT18	Q02156	PRKCE	T425	D424Y	424	Missense	proximal	-1	no	15.867	16.591	EPSD	TCGA;ICGC;COSMIC;CCLE	13.948	Up-regulation
AGC_PKC_PKCh_PRKCE_ST	Q02156	PRKCE	Q02156	PRKCE	S234	V232L	232	Missense	proximal	-2	no	18.167	16.626	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	13.948	Down-regulation
AGC_PKC_PKCh_PRKCE_ST	Q02156	PRKCE	Q02156	PRKCE	S234	R236G	236	Missense	proximal	2	no	18.167	13.255	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	13.948	Loss
AGC_PKC_PKCh_PRKCE_ST	Q02156	PRKCE	Q02156	PRKCE	S316	P310L	310	Missense	distal	-6	no	14.918	14.898	PhosphoSitePlus;EPSD	TCGA;ICGC;COSMIC	13.948	Down-regulation
AGC_PKC_PKCh_PRKCE_ST	Q02156	PRKCE	Q02156	PRKCE	S339	E341K	341	Missense	proximal	2	no	9.437	16.104	EPSD	TCGA;ICGC;COSMIC	13.948	Gain
AGC_PKC_PKCh_PRKCE_ST	Q02156	PRKCE	Q02156	PRKCE	S368	E374K	374	Missense	distal	6	no	18.283	18.579	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	13.948	Up-regulation
AGC_PKC_PKCh_PRKCE_ST	Q02156	PRKCE	Q02156	PRKCE	S368	R364W	364	Missense	distal	-4	no	18.283	18.836	EPSD;PhosphoSitePlus	TCGA;ICGC	13.948	Up-regulation
AGC_PKC_PKCh_PRKCE_ST	Q02156	PRKCE	Q02156	PRKCE	S380	S381F	381	Missense	proximal	1	no	14.241	15.577	EPSD	TCGA;ICGC	13.948	Up-regulation
AGC_PKC_PKCh_PRKCE_ST	Q02156	PRKCE	Q02156	PRKCE	S380	R377L	377	Missense	distal	-3	no	14.241	7.309	EPSD	TCGA;ICGC;COSMIC	13.948	Loss
AGC_PKC_PKCh_PRKCE_ST	Q02156	PRKCE	Q02156	PRKCE	S380	E374K	374	Missense	distal	-6	no	14.241	14.318	EPSD	TCGA;ICGC;COSMIC	13.948	Up-regulation
AGC_PKC_PKCh_PRKCE_ST	Q02156	PRKCE	Q02156	PRKCE	T566	Y573C	573	Missense	distal	7	no	14.837	14.057	EPSD	TCGA	13.948	Down-regulation
AGC_PKC_PKCh_PRKCE_ST	Q02156	PRKCE	Q02156	PRKCE	S729	G727V	727	Missense	proximal	-2	no	18.653	17.680	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	13.948	Down-regulation
AGC_PKC_PKCh_PRKCE_ST	Q02156	PRKCE	Q02156	PRKCE	S729	D734E	734	Missense	distal	5	no	18.653	18.521	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	13.948	Down-regulation
AGC_PKC_PKCh_PRKCE_ST	Q96A00	PPP1R14A	Q02156	PRKCE	T38	R36C	36	Missense	proximal	-2	no	20.543	19.039	PhosphoSitePlus	TCGA;ICGC;COSMIC	13.948	Down-regulation
AGC_PKC_PKCh_PRKCE_ST	Q96A00	PPP1R14A	Q02156	PRKCE	T38	R44W	44	Missense	distal	6	no	20.543	21.578	PhosphoSitePlus	TCGA;ICGC;COSMIC	13.948	Up-regulation
AGC_PKC_PKCh_PRKCE_ST	Q96A00	PPP1R14A	Q02156	PRKCE	S128	P129T	129	Missense	proximal	1	no	13.985	14.568	EPSD	TCGA;COSMIC	13.948	Up-regulation
AGC_PKC_PKCh_PRKCE_ST	Q96A00	PPP1R14A	Q02156	PRKCE	S134	L138P	138	Missense	distal	4	no	15.057	15.560	EPSD	TCGA;ICGC	13.948	Up-regulation
AGC_PKC_PKCh_PRKCE_ST	Q96A00	PPP1R14A	Q02156	PRKCE	S134	P129T	129	Missense	distal	-5	no	15.057	15.053	EPSD	TCGA;COSMIC	13.948	Down-regulation
AGC_PKC_PKCh_PRKCE_ST	Q96A00	PPP1R14A	Q02156	PRKCE	S136	L138P	138	Missense	proximal	2	no	17.416	19.267	EPSD	TCGA;ICGC	13.948	Up-regulation
AGC_PKC_PKCh_PRKCE_ST	Q96A00	PPP1R14A	Q02156	PRKCE	S136	P129T	129	Missense	distal	-7	no	17.416	17.304	EPSD	TCGA;COSMIC	13.948	Down-regulation
AGC_PKC_PKCh_PRKCE_ST	O94925	GLS	Q02156	PRKCE	S73	S75A	75	Missense	proximal	2	no	17.237	16.506	EPSD	TCGA;ICGC;COSMIC	13.948	Down-regulation
AGC_PKC_PKCh_PRKCE_ST	O94925	GLS	Q02156	PRKCE	S314	R317K	317	Missense	distal	3	no	16.352	16.561	PhosphoSitePlus	TCGA;ICGC;COSMIC	13.948	Up-regulation
AGC_PKC_PKCh_PRKCE_ST	O94925	GLS	Q02156	PRKCE	S314	R307Q	307	Missense	distal	-7	no	16.352	16.171	PhosphoSitePlus	TCGA;ICGC	13.948	Down-regulation
AGC_PKC_PKCh_PRKCE_ST	P46940	IQGAP1	Q02156	PRKCE	S91	Y96C	96	Missense	distal	5	no	18.534	18.605	EPSD	TCGA;ICGC;COSMIC	13.948	Up-regulation
AGC_PKC_PKCh_PRKCE_ST	P46940	IQGAP1	Q02156	PRKCE	S280	E278K	278	Missense	proximal	-2	no	17.797	19.722	EPSD	TCGA;ICGC;COSMIC	13.948	Up-regulation
AGC_PKC_PKCh_PRKCE_ST	P46940	IQGAP1	Q02156	PRKCE	S360	S360N	360	Missense	central	0	yes	17.160	0.000	EPSD	TCGA;ICGC;COSMIC	13.948	Loss
AGC_PKC_PKCh_PRKCE_ST	P46940	IQGAP1	Q02156	PRKCE	S480	S481G	481	Missense	proximal	1	no	15.354	15.972	EPSD	TCGA;ICGC;COSMIC	13.948	Up-regulation
AGC_PKC_PKCh_PRKCE_ST	P46940	IQGAP1	Q02156	PRKCE	S814	A816V	816	Missense	proximal	2	no	11.856	14.275	EPSD	TCGA;COSMIC	13.948	Gain
AGC_PKC_PKCh_PRKCE_ST	P46940	IQGAP1	Q02156	PRKCE	S962	A960V	960	Missense	proximal	-2	no	14.637	14.801	EPSD	TCGA;ICGC;COSMIC	13.948	Up-regulation
AGC_PKC_PKCh_PRKCE_ST	P46940	IQGAP1	Q02156	PRKCE	S962	E964D	964	Missense	proximal	2	no	14.637	15.252	EPSD	TCGA;ICGC;COSMIC	13.948	Up-regulation
AGC_PKC_PKCh_PRKCE_ST	P46940	IQGAP1	Q02156	PRKCE	S1237	L1242V	1242	Missense	distal	5	no	14.075	14.126	EPSD	TCGA;ICGC;COSMIC	13.948	Up-regulation
AGC_PKC_PKCh_PRKCE_ST	P46940	IQGAP1	Q02156	PRKCE	S1237	F1241Y	1241	Missense	distal	4	no	14.075	12.367	EPSD	TCGA;COSMIC	13.948	Loss
AGC_PKC_PKCh_PRKCE_ST	P46940	IQGAP1	Q02156	PRKCE	S1443	M1438I	1438	Missense	distal	-5	no	23.160	23.163	PhosphoSitePlus	TCGA;ICGC;COSMIC	13.948	Up-regulation
AGC_PKC_PKCh_PRKCE_ST	P46940	IQGAP1	Q02156	PRKCE	S1443	D1436A	1436	Missense	distal	-7	no	23.160	23.073	PhosphoSitePlus	TCGA;ICGC;COSMIC	13.948	Down-regulation
AGC_PKC_PKCh_PRKCE_ST	P05091	ALDH2	Q02156	PRKCE	S276	G275R	275	Missense	proximal	-1	no	15.744	15.909	EPSD	TCGA;COSMIC	13.948	Up-regulation
AGC_PKC_PKCh_PRKCE_ST	P05091	ALDH2	Q02156	PRKCE	S276	R281I	281	Missense	distal	5	no	15.744	16.138	EPSD	TCGA	13.948	Up-regulation
AGC_PKC_PKCh_PRKCE_ST	P05091	ALDH2	Q02156	PRKCE	T283	R281I	281	Missense	proximal	-2	no	14.529	12.077	EPSD	TCGA	13.948	Loss
AGC_PKC_PKCh_PRKCE_ST	P05091	ALDH2	Q02156	PRKCE	S296	N292S	292	Missense	distal	-4	no	14.408	14.412	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	13.948	Up-regulation
AGC_PKC_PKCh_PRKCE_ST	P05091	ALDH2	Q02156	PRKCE	S296	D301Y	301	Missense	distal	5	no	14.408	14.264	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	13.948	Down-regulation
AGC_PKC_PKCh_PRKCE_ST	Q15139	PRKD1	Q02156	PRKCE	T214	R216C	216	Missense	proximal	2	no	15.116	8.693	EPSD	TCGA;ICGC;COSMIC	13.948	Loss
AGC_PKC_PKCh_PRKCE_ST	Q15139	PRKD1	Q02156	PRKCE	T214	S213T	213	Missense	proximal	-1	no	15.116	14.720	EPSD	TCGA;ICGC;COSMIC	13.948	Down-regulation
AGC_PKC_PKCh_PRKCE_ST	Q15139	PRKD1	Q02156	PRKCE	T214	V212A	212	Missense	proximal	-2	no	15.116	14.952	EPSD	TCGA;ICGC	13.948	Down-regulation
AGC_PKC_PKCh_PRKCE_ST	Q15139	PRKD1	Q02156	PRKCE	T214	V212I	212	Missense	proximal	-2	no	15.116	14.228	EPSD	TCGA;ICGC;COSMIC	13.948	Down-regulation
AGC_PKC_PKCh_PRKCE_ST	Q15139	PRKD1	Q02156	PRKCE	S237	L231F	231	Missense	distal	-6	no	16.139	16.129	EPSD	TCGA;ICGC;COSMIC	13.948	Down-regulation
AGC_PKC_PKCh_PRKCE_ST	Q15139	PRKD1	Q02156	PRKCE	S401	L406I	406	Missense	distal	5	no	13.976	14.184	EPSD	TCGA;COSMIC	13.948	Up-regulation
AGC_PKC_PKCh_PRKCE_ST	Q15139	PRKD1	Q02156	PRKCE	S401	P398S	398	Missense	distal	-3	no	13.976	17.294	EPSD	TCGA;COSMIC	13.948	Up-regulation
AGC_PKC_PKCh_PRKCE_ST	Q15139	PRKD1	Q02156	PRKCE	S401	P398L	398	Missense	distal	-3	no	13.976	15.131	EPSD	TCGA;COSMIC	13.948	Up-regulation
AGC_PKC_PKCh_PRKCE_ST	Q15139	PRKD1	Q02156	PRKCE	S412	K414N	414	Missense	proximal	2	no	14.595	8.139	EPSD	TCGA	13.948	Loss
AGC_PKC_PKCh_PRKCE_ST	Q15139	PRKD1	Q02156	PRKCE	S412	L406I	406	Missense	distal	-6	no	14.595	14.626	EPSD	TCGA;COSMIC	13.948	Up-regulation
AGC_PKC_PKCh_PRKCE_ST	Q15139	PRKD1	Q02156	PRKCE	S738	R740Q	740	Missense	proximal	2	no	20.516	15.284	PhosphoSitePlus;EPSD	TCGA;ICGC;COSMIC	13.948	Down-regulation
AGC_PKC_PKCh_PRKCE_ST	Q15139	PRKD1	Q02156	PRKCE	S738	R732Q	732	Missense	distal	-6	no	20.516	20.412	PhosphoSitePlus;EPSD	TCGA;COSMIC	13.948	Down-regulation
AGC_PKC_PKCh_PRKCE_ST	Q15139	PRKD1	Q02156	PRKCE	S738	R732L	732	Missense	distal	-6	no	20.516	20.369	PhosphoSitePlus;EPSD	TCGA;COSMIC	13.948	Down-regulation
AGC_PKC_PKCh_PRKCE_ST	Q15139	PRKD1	Q02156	PRKCE	S738	R732W	732	Missense	distal	-6	no	20.516	20.226	PhosphoSitePlus;EPSD	TCGA;COSMIC	13.948	Down-regulation
AGC_PKC_PKCh_PRKCE_ST	Q15139	PRKD1	Q02156	PRKCE	S742	R740Q	740	Missense	proximal	-2	no	17.260	16.289	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	13.948	Down-regulation
AGC_PKC_PKCh_PRKCE_ST	Q15139	PRKD1	Q02156	PRKCE	S742	P747T	747	Missense	distal	5	no	17.260	17.469	EPSD;PhosphoSitePlus	TCGA;COSMIC	13.948	Up-regulation
AGC_PKC_PKCh_PRKCE_ST	Q15139	PRKD1	Q02156	PRKCE	S742	A748S	748	Missense	distal	6	no	17.260	17.451	EPSD;PhosphoSitePlus	TCGA;COSMIC	13.948	Up-regulation
AGC_PKC_PKCh_PRKCE_ST	Q15139	PRKD1	Q02156	PRKCE	S742	T746A	746	Missense	distal	4	no	17.260	17.002	EPSD;PhosphoSitePlus	TCGA	13.948	Down-regulation
AGC_PKC_PKCh_PRKCE_ST	Q15139	PRKD1	Q02156	PRKCE	S829	V822L	822	Missense	distal	-7	no	18.738	18.800	EPSD	TCGA;COSMIC	13.948	Up-regulation
AGC_PKC_PKCh_PRKCE_ST	Q15139	PRKD1	Q02156	PRKCE	S829	R827H	827	Missense	proximal	-2	no	18.738	16.189	EPSD	TCGA;COSMIC	13.948	Down-regulation
AGC_PKC_PKCh_PRKCE_ST	Q15139	PRKD1	Q02156	PRKCE	S829	H836N	836	Missense	distal	7	no	18.738	19.312	EPSD	TCGA;COSMIC	13.948	Up-regulation
AGC_PKC_PKCh_PRKCE_ST	Q15139	PRKD1	Q02156	PRKCE	S829	H836L	836	Missense	distal	7	no	18.738	18.760	EPSD	TCGA;COSMIC	13.948	Up-regulation
AGC_PKC_PKCh_PRKCE_ST	Q15139	PRKD1	Q02156	PRKCE	S829	R827C	827	Missense	proximal	-2	no	18.738	17.235	EPSD	TCGA;COSMIC	13.948	Down-regulation
AGC_PKC_PKCh_PRKCE_ST	Q15139	PRKD1	Q02156	PRKCE	S829	K826N	826	Missense	distal	-3	no	18.738	11.364	EPSD	TCGA	13.948	Loss
AGC_PKC_PKCh_PRKCE_ST	Q15139	PRKD1	Q02156	PRKCE	T894	E896K	896	Missense	proximal	2	no	9.713	16.380	EPSD	TCGA;COSMIC	13.948	Gain
AGC_PKC_PKCh_PRKCE_ST	P00533	EGFR	Q02156	PRKCE	S227	R222C	222	Missense	distal	-5	no	14.792	14.814	EPSD	TCGA;COSMIC	13.948	Up-regulation
AGC_PKC_PKCh_PRKCE_ST	P00533	EGFR	Q02156	PRKCE	S227	S229C	229	Missense	proximal	2	no	14.792	14.806	EPSD	TCGA;COSMIC	13.948	Up-regulation
AGC_PKC_PKCh_PRKCE_ST	P00533	EGFR	Q02156	PRKCE	S227	C223Y	223	Missense	distal	-4	no	14.792	14.615	EPSD	TCGA;COSMIC	13.948	Down-regulation
AGC_PKC_PKCh_PRKCE_ST	P00533	EGFR	Q02156	PRKCE	S227	R222L	222	Missense	distal	-5	no	14.792	14.805	EPSD	TCGA;COSMIC	13.948	Up-regulation
AGC_PKC_PKCh_PRKCE_ST	P00533	EGFR	Q02156	PRKCE	S227	S227F	227	Missense	central	0	yes	14.792	0.000	EPSD	TCGA;COSMIC	13.948	Loss
AGC_PKC_PKCh_PRKCE_ST	P00533	EGFR	Q02156	PRKCE	S227	P228L	228	Missense	proximal	1	no	14.792	16.156	EPSD	TCGA;COSMIC	13.948	Up-regulation
AGC_PKC_PKCh_PRKCE_ST	P00533	EGFR	Q02156	PRKCE	S227	N234S	234	Missense	distal	7	no	14.792	14.698	EPSD	TCGA;COSMIC	13.948	Down-regulation
AGC_PKC_PKCh_PRKCE_ST	P00533	EGFR	Q02156	PRKCE	S227	R224H	224	Missense	distal	-3	no	14.792	9.573	EPSD	TCGA;COSMIC	13.948	Loss
AGC_PKC_PKCh_PRKCE_ST	P00533	EGFR	Q02156	PRKCE	S457	S464P	464	Missense	distal	7	no	15.828	15.207	EPSD	TCGA;COSMIC	13.948	Down-regulation
AGC_PKC_PKCh_PRKCE_ST	P00533	EGFR	Q02156	PRKCE	T678	R675W	675	Missense	distal	-3	no	15.967	4.970	PhosphoSitePlus	TCGA	13.948	Loss
AGC_PKC_PKCh_PRKCE_ST	P00533	EGFR	Q02156	PRKCE	T678	R677H	677	Missense	proximal	-1	no	15.967	14.630	PhosphoSitePlus	TCGA;COSMIC	13.948	Down-regulation
AGC_PKC_PKCh_PRKCE_ST	P00533	EGFR	Q02156	PRKCE	T678	R681M	681	Missense	distal	3	no	15.967	15.935	PhosphoSitePlus	TCGA	13.948	Down-regulation
AGC_PKC_PKCh_PRKCE_ST	P00533	EGFR	Q02156	PRKCE	T678	Q684H	684	Missense	distal	6	no	15.967	16.354	PhosphoSitePlus	TCGA	13.948	Up-regulation
AGC_PKC_PKCh_PRKCE_ST	P00533	EGFR	Q02156	PRKCE	T678	T678M	678	Missense	central	0	yes	15.967	0.000	PhosphoSitePlus	TCGA;GDSC;CCLE	13.948	Loss
AGC_PKC_PKCh_PRKCE_ST	P00533	EGFR	Q02156	PRKCE	S752	I759N	759	Missense	distal	7	no	14.001	14.205	EPSD	TCGA;COSMIC	13.948	Up-regulation
AGC_PKC_PKCh_PRKCE_ST	P00533	EGFR	Q02156	PRKCE	S752	K754E	754	Missense	proximal	2	no	14.001	7.334	EPSD	TCGA;COSMIC	13.948	Loss
AGC_PKC_PKCh_PRKCE_ST	P00533	EGFR	Q02156	PRKCE	S752	K754I	754	Missense	proximal	2	no	14.001	6.512	EPSD	TCGA;COSMIC	13.948	Loss
AGC_PKC_PKCh_PRKCE_ST	P00533	EGFR	Q02156	PRKCE	S752	P753L	753	Missense	proximal	1	no	14.001	15.365	EPSD	TCGA;COSMIC	13.948	Up-regulation
AGC_PKC_PKCh_PRKCE_ST	P00533	EGFR	Q02156	PRKCE	S752	P753S	753	Missense	proximal	1	no	14.001	15.130	EPSD	TCGA;COSMIC;GDSC;CCLE	13.948	Up-regulation
AGC_PKC_PKCh_PRKCE_ST	P00533	EGFR	Q02156	PRKCE	T892	H893Y	893	Missense	proximal	1	no	10.086	14.237	EPSD	TCGA;COSMIC	13.948	Gain
AGC_PKC_PKCh_PRKCE_ST	P00533	EGFR	Q02156	PRKCE	S925	E922K	922	Missense	distal	-3	no	7.315	14.442	EPSD	TCGA;COSMIC	13.948	Gain
AGC_PKC_PKCh_PRKCE_ST	P00533	EGFR	Q02156	PRKCE	S1064	R1068Q	1068	Missense	distal	4	no	14.638	14.107	EPSD	TCGA;COSMIC	13.948	Down-regulation
AGC_PKC_PKCh_PRKCE_ST	P00533	EGFR	Q02156	PRKCE	S1190	G1185V	1185	Missense	distal	-5	no	15.423	15.412	EPSD	TCGA;ICGC;COSMIC	13.948	Down-regulation
AGC_PKC_PKCh_PRKCE_ST	P00533	EGFR	Q02156	PRKCE	S1190	A1195T	1195	Missense	distal	5	no	15.423	15.481	EPSD	TCGA;ICGC	13.948	Up-regulation
AGC_PKC_PKCh_PRKCE_ST	P00533	EGFR	Q02156	PRKCE	T1191	G1185V	1185	Missense	distal	-6	no	16.207	16.209	EPSD	TCGA;ICGC;COSMIC	13.948	Up-regulation
AGC_PKC_PKCh_PRKCE_ST	P00533	EGFR	Q02156	PRKCE	T1191	A1195T	1195	Missense	distal	4	no	16.207	16.464	EPSD	TCGA;ICGC	13.948	Up-regulation
AGC_PKC_PKCh_PRKCE_ST	P00533	EGFR	Q02156	PRKCE	S1204	A1201V	1201	Missense	distal	-3	no	19.460	17.313	EPSD	TCGA;ICGC;COSMIC	13.948	Down-regulation
AGC_PKC_PKCh_PRKCE_ST	Q9BR76	CORO1B	Q02156	PRKCE	T209	R207W	207	Missense	proximal	-2	no	15.144	11.926	EPSD	TCGA;ICGC;COSMIC	13.948	Loss
AGC_PKC_PKCh_PRKCE_ST	Q9BR76	CORO1B	Q02156	PRKCE	T209	G208D	208	Missense	proximal	-1	no	15.144	14.731	EPSD	TCGA;ICGC;COSMIC	13.948	Down-regulation
AGC_PKC_PKCh_PRKCE_ST	Q9BR76	CORO1B	Q02156	PRKCE	S423	R416W	416	Missense	distal	-7	no	14.321	13.737	EPSD	TCGA;ICGC;COSMIC	13.948	Loss
AGC_PKC_PKCh_PRKCE_ST	Q5JXC2	MIIP	Q02156	PRKCE	S113	R110S	110	Missense	distal	-3	no	16.008	11.240	EPSD	TCGA;ICGC;COSMIC	13.948	Loss
AGC_PKC_PKCh_PRKCE_ST	Q5JXC2	MIIP	Q02156	PRKCE	S113	P111L	111	Missense	proximal	-2	no	16.008	13.576	EPSD	TCGA;ICGC;COSMIC	13.948	Loss
AGC_PKC_PKCh_PRKCE_ST	Q5JXC2	MIIP	Q02156	PRKCE	S113	A114V	114	Missense	proximal	1	no	16.008	16.429	EPSD	TCGA	13.948	Up-regulation
AGC_PKC_PKCh_PRKCE_ST	Q5JXC2	MIIP	Q02156	PRKCE	S113	P109L	109	Missense	distal	-4	no	16.008	16.012	EPSD	TCGA;ICGC;COSMIC	13.948	Up-regulation
AGC_PKC_PKCh_PRKCE_ST	Q5JXC2	MIIP	Q02156	PRKCE	S303	R300W	300	Missense	distal	-3	no	18.987	7.990	PhosphoSitePlus	TCGA;ICGC;COSMIC	13.948	Loss
AGC_PKC_PKCh_PRKCE_ST	Q5JXC2	MIIP	Q02156	PRKCE	S303	F304C	304	Missense	proximal	1	no	18.987	16.485	PhosphoSitePlus	TCGA;ICGC;COSMIC	13.948	Down-regulation
AGC_PKC_PKCh_PRKCE_ST	Q5JXC2	MIIP	Q02156	PRKCE	S303	K302N	302	Missense	proximal	-1	no	18.987	18.753	PhosphoSitePlus	TCGA;ICGC;COSMIC	13.948	Down-regulation
AGC_PKC_PKCh_PRKCE_ST	P62491	RAB11A	Q02156	PRKCE	S177	S177F	177	Missense	central	0	yes	19.438	0.000	PhosphoSitePlus	TCGA;ICGC;COSMIC	13.948	Loss
AGC_PKC_PKCh_PRKCE_ST	P62491	RAB11A	Q02156	PRKCE	S177	R174H	174	Missense	distal	-3	no	19.438	14.219	PhosphoSitePlus	TCGA;ICGC;COSMIC	13.948	Down-regulation
AGC_PKC_PKCh_PRKCE_ST	P62491	RAB11A	Q02156	PRKCE	S177	E171D	171	Missense	distal	-6	no	19.438	19.472	PhosphoSitePlus	TCGA;ICGC	13.948	Up-regulation
AGC_PKC_PKCh_PRKCE_ST	P20339	RAB5A	Q02156	PRKCE	T7	A6T	6	Missense	proximal	-1	no	17.367	17.175	PhosphoSitePlus	TCGA;ICGC;COSMIC;GDSC;CCLE	13.948	Down-regulation
AGC_PKC_PKCh_PRKCE_ST	P20339	RAB5A	Q02156	PRKCE	S123	S123N	123	Missense	central	0	yes	16.300	0.000	EPSD	TCGA;ICGC;COSMIC	13.948	Loss
AGC_PKC_PKCh_PRKCE_ST	P20339	RAB5A	Q02156	PRKCE	S193	A191S	191	Missense	proximal	-2	no	14.772	15.689	EPSD	TCGA;ICGC;COSMIC	13.948	Up-regulation
AGC_PKC_PKCh_PRKCE_ST	P20339	RAB5A	Q02156	PRKCE	S193	V199I	199	Missense	distal	6	no	14.772	14.718	EPSD	TCGA;ICGC;COSMIC	13.948	Down-regulation
AGC_PKC_PKCh_PRKCE_ST	P20339	RAB5A	Q02156	PRKCE	S193	P189S	189	Missense	distal	-4	no	14.772	14.862	EPSD	TCGA;ICGC;COSMIC	13.948	Up-regulation
AGC_PKC_PKCh_PRKCE_ST	P20339	RAB5A	Q02156	PRKCE	T205	V199I	199	Missense	distal	-6	no	15.821	15.801	EPSD	TCGA;ICGC;COSMIC	13.948	Down-regulation
AGC_PKC_PKCh_PRKCE_ST	P05556	ITGB1	Q02156	PRKCE	S327	H321Y	321	Missense	distal	-6	no	14.061	14.174	EPSD	TCGA;ICGC;COSMIC	13.948	Up-regulation
AGC_PKC_PKCh_PRKCE_ST	P05556	ITGB1	Q02156	PRKCE	S549	E546K	546	Missense	distal	-3	no	12.389	19.515	EPSD	TCGA;ICGC;COSMIC	13.948	Gain
AGC_PKC_PKCh_PRKCE_ST	P05556	ITGB1	Q02156	PRKCE	S785	P781S	781	Missense	distal	-4	no	16.060	16.149	EPSD	TCGA;ICGC;COSMIC	13.948	Up-regulation
AGC_PKC_PKCh_PRKCE_ST	P05556	ITGB1	Q02156	PRKCE	S785	T789I	789	Missense	distal	4	no	16.060	15.757	EPSD	TCGA;ICGC;COSMIC	13.948	Down-regulation
AGC_PKC_PKCh_PRKCE_ST	P05556	ITGB1	Q02156	PRKCE	T788	P781S	781	Missense	distal	-7	no	15.986	16.112	PhosphoSitePlus;EPSD	TCGA;ICGC;COSMIC	13.948	Up-regulation
AGC_PKC_PKCh_PRKCE_ST	P05556	ITGB1	Q02156	PRKCE	T788	P793L	793	Missense	distal	5	no	15.986	15.864	PhosphoSitePlus;EPSD	TCGA;ICGC;COSMIC	13.948	Down-regulation
AGC_PKC_PKCh_PRKCE_ST	P05556	ITGB1	Q02156	PRKCE	T788	T789I	789	Missense	proximal	1	no	15.986	17.288	PhosphoSitePlus;EPSD	TCGA;ICGC;COSMIC	13.948	Up-regulation
AGC_PKC_PKCh_PRKCE_ST	P05556	ITGB1	Q02156	PRKCE	T789	P793L	793	Missense	distal	4	no	14.997	14.494	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	13.948	Down-regulation
AGC_PKC_PKCh_PRKCE_ST	P05556	ITGB1	Q02156	PRKCE	T789	T789I	789	Missense	central	0	yes	14.997	0.000	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	13.948	Loss
AGC_PKC_PKCh_PRKCE_ST	Q96GD4	AURKB	Q02156	PRKCE	S62	E59K	59	Missense	distal	-3	no	7.840	14.966	EPSD	TCGA;ICGC;COSMIC	13.948	Gain
AGC_PKC_PKCh_PRKCE_ST	Q96GD4	AURKB	Q02156	PRKCE	S227	R230S	230	Missense	distal	3	no	15.734	15.486	PhosphoSitePlus	TCGA;COSMIC	13.948	Down-regulation
AGC_PKC_PKCh_PRKCE_ST	Q96GD4	AURKB	Q02156	PRKCE	S331	P336L	336	Missense	distal	5	no	27.336	27.213	EPSD	TCGA;COSMIC	13.948	Down-regulation
AGC_PKC_PKCh_PRKCE_ST	Q96GD4	AURKB	Q02156	PRKCE	S331	R332Q	332	Missense	proximal	1	no	27.336	26.100	EPSD	TCGA;COSMIC	13.948	Down-regulation
AGC_PKC_PKCh_PRKCE_ST	P28329	CHAT	Q02156	PRKCE	T373	D379Y	379	Missense	distal	6	no	16.395	16.482	EPSD	TCGA;COSMIC	13.948	Up-regulation
AGC_PKC_PKCh_PRKCE_ST	P28329	CHAT	Q02156	PRKCE	T373	S377L	377	Missense	distal	4	no	16.395	15.766	EPSD	TCGA;COSMIC	13.948	Down-regulation
AGC_PKC_PKCh_PRKCE_ST	P28329	CHAT	Q02156	PRKCE	S464	R466K	466	Missense	proximal	2	no	13.487	14.169	EPSD	TCGA;COSMIC	13.948	Gain
AGC_PKC_PKCh_PRKCE_ST	P28329	CHAT	Q02156	PRKCE	S473	V474I	474	Missense	proximal	1	no	15.176	16.211	EPSD	TCGA;COSMIC;CCLE	13.948	Up-regulation
AGC_PKC_PKCh_PRKCE_ST	P28329	CHAT	Q02156	PRKCE	S473	S473Y	473	Missense	central	0	yes	15.176	0.000	EPSD	TCGA;COSMIC	13.948	Loss
AGC_PKC_PKCh_PRKCE_ST	P28329	CHAT	Q02156	PRKCE	S473	P478R	478	Missense	distal	5	no	15.176	14.867	EPSD	TCGA;COSMIC	13.948	Down-regulation
AGC_PKC_PKCh_PRKCE_ST	P28329	CHAT	Q02156	PRKCE	S473	P478H	478	Missense	distal	5	no	15.176	15.232	EPSD	TCGA;COSMIC	13.948	Up-regulation
AGC_PKC_PKCh_PRKCE_ST	P28329	CHAT	Q02156	PRKCE	S473	R470Q	470	Missense	distal	-3	no	15.176	9.610	EPSD	TCGA;COSMIC	13.948	Loss
AGC_PKC_PKCh_PRKCE_ST	P28329	CHAT	Q02156	PRKCE	S473	R466K	466	Missense	distal	-7	no	15.176	14.956	EPSD	TCGA;COSMIC	13.948	Down-regulation
AGC_PKC_PKCh_PRKCE_ST	P28329	CHAT	Q02156	PRKCE	S473	E476K	476	Missense	distal	3	no	15.176	15.803	EPSD	TCGA;COSMIC	13.948	Up-regulation
AGC_PKC_PKCh_PRKCE_ST	P28329	CHAT	Q02156	PRKCE	S558	A557V	557	Missense	proximal	-1	no	17.756	17.559	EPSD	TCGA;COSMIC	13.948	Down-regulation
AGC_PKC_PKCh_PRKCE_ST	P28329	CHAT	Q02156	PRKCE	S558	P552L	552	Missense	distal	-6	no	17.756	17.736	EPSD	TCGA;COSMIC	13.948	Down-regulation
AGC_PKC_PKCh_PRKCE_ST	P28329	CHAT	Q02156	PRKCE	S558	S556R	556	Missense	proximal	-2	no	17.756	18.567	EPSD	TCGA;COSMIC	13.948	Up-regulation
AGC_PKC_PKCh_PRKCE_ST	P28329	CHAT	Q02156	PRKCE	S558	G565E	565	Missense	distal	7	no	17.756	18.214	EPSD	TCGA;COSMIC	13.948	Up-regulation
AGC_PKC_PKCh_PRKCE_ST	P28329	CHAT	Q02156	PRKCE	T574	S572L	572	Missense	proximal	-2	no	17.341	15.048	EPSD	TCGA;COSMIC;CCLE	13.948	Down-regulation
AGC_PKC_PKCh_PRKCE_ST	P28329	CHAT	Q02156	PRKCE	T574	R571I	571	Missense	distal	-3	no	17.341	13.144	EPSD	TCGA;COSMIC	13.948	Loss
AGC_PKC_PKCh_PRKCE_ST	P28329	CHAT	Q02156	PRKCE	S730	A734T	734	Missense	distal	4	no	13.895	14.153	EPSD	TCGA;COSMIC	13.948	Gain
AGC_PKC_PKCh_PRKCE_ST	P28329	CHAT	Q02156	PRKCE	S730	E737K	737	Missense	distal	7	no	13.895	14.712	EPSD	TCGA;COSMIC;GDSC;CCLE	13.948	Gain
AGC_PKC_PKCh_PRKCE_ST	P17302	GJA1	Q02156	PRKCE	S244	R239Q	239	Missense	distal	-5	no	15.603	15.614	EPSD	TCGA;ICGC;COSMIC	13.948	Up-regulation
AGC_PKC_PKCh_PRKCE_ST	P17302	GJA1	Q02156	PRKCE	S244	G242E	242	Missense	proximal	-2	no	15.603	14.703	EPSD	TCGA;ICGC;COSMIC	13.948	Down-regulation
AGC_PKC_PKCh_PRKCE_ST	P17302	GJA1	Q02156	PRKCE	S244	R239W	239	Missense	distal	-5	no	15.603	15.672	EPSD	TCGA;ICGC;COSMIC	13.948	Up-regulation
AGC_PKC_PKCh_PRKCE_ST	P17302	GJA1	Q02156	PRKCE	S244	D245N	245	Missense	proximal	1	no	15.603	14.285	EPSD	TCGA	13.948	Down-regulation
AGC_PKC_PKCh_PRKCE_ST	P17302	GJA1	Q02156	PRKCE	S262	Q263K	263	Missense	proximal	1	no	13.473	15.698	EPSD	TCGA;ICGC;COSMIC	13.948	Gain
AGC_PKC_PKCh_PRKCE_ST	P17302	GJA1	Q02156	PRKCE	S296	R299H	299	Missense	distal	3	no	17.123	16.209	EPSD	TCGA;COSMIC	13.948	Down-regulation
AGC_PKC_PKCh_PRKCE_ST	P17302	GJA1	Q02156	PRKCE	S296	R293K	293	Missense	distal	-3	no	17.123	17.140	EPSD	TCGA;ICGC;COSMIC	13.948	Up-regulation
AGC_PKC_PKCh_PRKCE_ST	P17302	GJA1	Q02156	PRKCE	S296	C298S	298	Missense	proximal	2	no	17.123	17.109	EPSD	TCGA;ICGC;COSMIC	13.948	Down-regulation
AGC_PKC_PKCh_PRKCE_ST	P17302	GJA1	Q02156	PRKCE	S296	S296F	296	Missense	central	0	yes	17.123	0.000	EPSD	TCGA;ICGC;COSMIC	13.948	Loss
AGC_PKC_PKCh_PRKCE_ST	P17302	GJA1	Q02156	PRKCE	S296	S296Y	296	Missense	central	0	yes	17.123	0.000	EPSD	TCGA;ICGC	13.948	Loss
AGC_PKC_PKCh_PRKCE_ST	P17302	GJA1	Q02156	PRKCE	S364	V359L	359	Missense	distal	-5	no	23.628	23.635	EPSD	TCGA;ICGC;COSMIC	13.948	Up-regulation
AGC_PKC_PKCh_PRKCE_ST	P17302	GJA1	Q02156	PRKCE	S364	S369N	369	Missense	distal	5	no	23.628	23.730	EPSD	TCGA;ICGC;COSMIC	13.948	Up-regulation
AGC_PKC_PKCh_PRKCE_ST	P17302	GJA1	Q02156	PRKCE	S365	V359L	359	Missense	distal	-6	no	18.789	18.738	EPSD	TCGA;ICGC;COSMIC	13.948	Down-regulation
AGC_PKC_PKCh_PRKCE_ST	P17302	GJA1	Q02156	PRKCE	S365	S369N	369	Missense	distal	4	no	18.789	17.880	EPSD	TCGA;ICGC;COSMIC	13.948	Down-regulation
AGC_PKC_PKCh_PRKCE_ST	P17302	GJA1	Q02156	PRKCE	S368	S369N	369	Missense	proximal	1	no	25.616	24.406	PhosphoSitePlus	TCGA;ICGC;COSMIC	13.948	Down-regulation
AGC_PKC_PKCh_PRKCE_ST	P17302	GJA1	Q02156	PRKCE	S369	S369N	369	Missense	central	0	yes	20.672	0.000	EPSD	TCGA;ICGC;COSMIC	13.948	Loss
AGC_PKC_PKCh_PRKCE_ST	P17302	GJA1	Q02156	PRKCE	S372	S369N	369	Missense	distal	-3	no	28.412	25.825	EPSD	TCGA;ICGC;COSMIC	13.948	Down-regulation
AGC_PKC_PKCh_PRKCE_ST	P17302	GJA1	Q02156	PRKCE	S373	S369N	369	Missense	distal	-4	no	21.819	21.815	EPSD	TCGA;ICGC;COSMIC	13.948	Down-regulation
AGC_PKC_PKCh_PRKCE_ST	Q9BZL6	PRKD2	Q02156	PRKCE	S206	T199M	199	Missense	distal	-7	no	13.572	14.120	EPSD	TCGA	13.948	Gain
AGC_PKC_PKCh_PRKCE_ST	Q9BZL6	PRKD2	Q02156	PRKCE	T226	E228K	228	Missense	proximal	2	no	8.843	15.510	EPSD	TCGA;COSMIC;CCLE	13.948	Gain
AGC_PKC_PKCh_PRKCE_ST	Q9BZL6	PRKD2	Q02156	PRKCE	T412	N409I	409	Missense	distal	-3	no	12.866	16.025	EPSD	TCGA;COSMIC	13.948	Gain
AGC_PKC_PKCh_PRKCE_ST	Q9BZL6	PRKD2	Q02156	PRKCE	S529	S529F	529	Missense	central	0	yes	14.764	0.000	EPSD	TCGA;COSMIC	13.948	Loss
AGC_PKC_PKCh_PRKCE_ST	Q9BZL6	PRKD2	Q02156	PRKCE	S706	R709H	709	Missense	distal	3	no	20.395	19.481	EPSD;PhosphoSitePlus	TCGA;COSMIC	13.948	Down-regulation
AGC_PKC_PKCh_PRKCE_ST	Q9BZL6	PRKD2	Q02156	PRKCE	S706	S706L	706	Missense	central	0	yes	20.395	0.000	EPSD;PhosphoSitePlus	TCGA;COSMIC	13.948	Loss
AGC_PKC_PKCh_PRKCE_ST	Q9BZL6	PRKD2	Q02156	PRKCE	S710	A716T	716	Missense	distal	6	no	17.665	17.912	EPSD;PhosphoSitePlus	TCGA;COSMIC	13.948	Up-regulation
AGC_PKC_PKCh_PRKCE_ST	Q9BZL6	PRKD2	Q02156	PRKCE	S710	R709H	709	Missense	proximal	-1	no	17.665	16.328	EPSD;PhosphoSitePlus	TCGA;COSMIC	13.948	Down-regulation
AGC_PKC_PKCh_PRKCE_ST	Q9BZL6	PRKD2	Q02156	PRKCE	S710	S706L	706	Missense	distal	-4	no	17.665	17.579	EPSD;PhosphoSitePlus	TCGA;COSMIC	13.948	Down-regulation
AGC_PKC_PKCh_PRKCE_ST	Q9BZL6	PRKD2	Q02156	PRKCE	S710	P715S	715	Missense	distal	5	no	17.665	17.557	EPSD;PhosphoSitePlus	TCGA;COSMIC	13.948	Down-regulation
AGC_PKC_PKCh_PRKCE_ST	Q9BZL6	PRKD2	Q02156	PRKCE	S797	R793H	793	Missense	distal	-4	no	17.680	18.145	EPSD	TCGA;COSMIC	13.948	Up-regulation
AGC_PKC_PKCh_PRKCE_ST	Q9BZL6	PRKD2	Q02156	PRKCE	S797	K794T	794	Missense	distal	-3	no	17.680	13.087	EPSD	TCGA	13.948	Loss
AGC_PKC_PKCh_PRKCE_ST	Q9BZL6	PRKD2	Q02156	PRKCE	S797	S801F	801	Missense	distal	4	no	17.680	18.063	EPSD	TCGA;COSMIC	13.948	Up-regulation
AGC_PKC_PKCh_PRKCE_ST	Q9BZL6	PRKD2	Q02156	PRKCE	S797	R795H	795	Missense	proximal	-2	no	17.680	15.130	EPSD	TCGA;COSMIC	13.948	Down-regulation
AGC_PKC_PKCh_PRKCE_ST	Q9BZL6	PRKD2	Q02156	PRKCE	S797	S803G	803	Missense	distal	6	no	17.680	17.601	EPSD	TCGA;COSMIC	13.948	Down-regulation
AGC_PKC_PKCh_PRKCE_ST	Q9BZL6	PRKD2	Q02156	PRKCE	S876	R874H	874	Missense	proximal	-2	no	15.012	12.462	PhosphoSitePlus;EPSD	TCGA;COSMIC	13.948	Loss
AGC_PKC_PKCh_PRKCE_ST	Q9BZL6	PRKD2	Q02156	PRKCE	S876	R874C	874	Missense	proximal	-2	no	15.012	13.508	PhosphoSitePlus;EPSD	TCGA;COSMIC;GDSC;CCLE	13.948	Loss
AGC_PKC_PKCh_PRKCE_ST	P40763	STAT3	Q02156	PRKCE	S25	S25N	25	Missense	central	0	yes	14.117	0.000	EPSD	TCGA;COSMIC	13.948	Loss
AGC_PKC_PKCh_PRKCE_ST	P40763	STAT3	Q02156	PRKCE	S25	R31Q	31	Missense	distal	6	no	14.117	14.417	EPSD	TCGA;ICGC;COSMIC	13.948	Up-regulation
AGC_PKC_PKCh_PRKCE_ST	P40763	STAT3	Q02156	PRKCE	S25	M28K	28	Missense	distal	3	no	14.117	14.357	EPSD	TCGA;ICGC;COSMIC	13.948	Up-regulation
AGC_PKC_PKCh_PRKCE_ST	P40763	STAT3	Q02156	PRKCE	S25	L21V	21	Missense	distal	-4	no	14.117	14.081	EPSD	TCGA	13.948	Down-regulation
AGC_PKC_PKCh_PRKCE_ST	P40763	STAT3	Q02156	PRKCE	T412	S405F	405	Missense	distal	-7	no	16.928	16.651	EPSD	TCGA;ICGC;COSMIC	13.948	Down-regulation
AGC_PKC_PKCh_PRKCE_ST	P40763	STAT3	Q02156	PRKCE	T412	H410R	410	Missense	proximal	-2	no	16.928	19.478	EPSD	TCGA;ICGC;COSMIC	13.948	Up-regulation
AGC_PKC_PKCh_PRKCE_ST	P40763	STAT3	Q02156	PRKCE	T412	A406V	406	Missense	distal	-6	no	16.928	16.971	EPSD	TCGA;ICGC;COSMIC;GDSC;CCLE	13.948	Up-regulation
AGC_PKC_PKCh_PRKCE_ST	P40763	STAT3	Q02156	PRKCE	S636	E638K	638	Missense	proximal	2	no	9.879	16.545	EPSD	TCGA;ICGC;COSMIC	13.948	Gain
AGC_PKC_PKCh_PRKCE_ST	P40763	STAT3	Q02156	PRKCE	S691	Y686D	686	Missense	distal	-5	no	14.277	14.288	EPSD	TCGA;ICGC	13.948	Up-regulation
AGC_PKC_PKCh_PRKCE_ST	P40763	STAT3	Q02156	PRKCE	S727	R729H	729	Missense	proximal	2	no	18.269	11.298	PhosphoSitePlus	TCGA;ICGC;COSMIC;GDSC;CCLE	13.948	Loss
AGC_PKC_PKCh_PRKCE_ST	P40763	STAT3	Q02156	PRKCE	S727	P725L	725	Missense	proximal	-2	no	18.269	15.837	PhosphoSitePlus	TCGA;ICGC;COSMIC	13.948	Down-regulation
AGC_PKC_PKCh_PRKCE_ST	O14920	IKBKB	Q02156	PRKCE	S177	G176D	176	Missense	proximal	-1	no	16.356	15.943	PhosphoSitePlus	TCGA;COSMIC	13.948	Down-regulation
AGC_PKC_PKCh_PRKCE_ST	O14920	IKBKB	Q02156	PRKCE	S177	K171R	171	Missense	distal	-6	no	16.356	16.395	PhosphoSitePlus	TCGA;COSMIC	13.948	Up-regulation
AGC_PKC_PKCh_PRKCE_ST	O14920	IKBKB	Q02156	PRKCE	S177	V183M	183	Missense	distal	6	no	16.356	16.072	PhosphoSitePlus	TCGA;COSMIC	13.948	Down-regulation
AGC_PKC_PKCh_PRKCE_ST	O14920	IKBKB	Q02156	PRKCE	S257	Y261C	261	Missense	distal	4	no	14.353	13.397	EPSD	TCGA;COSMIC	13.948	Loss
AGC_PKC_PKCh_PRKCE_ST	O14920	IKBKB	Q02156	PRKCE	S257	T252M	252	Missense	distal	-5	no	14.353	14.374	EPSD	TCGA;COSMIC	13.948	Up-regulation
AGC_PKC_PKCh_PRKCE_ST	O14920	IKBKB	Q02156	PRKCE	S257	G251R	251	Missense	distal	-6	no	14.353	14.452	EPSD	TCGA;COSMIC	13.948	Up-regulation
AGC_PKC_PKCh_PRKCE_ST	O14920	IKBKB	Q02156	PRKCE	S335	L336F	336	Missense	proximal	1	no	14.390	15.491	EPSD	TCGA;COSMIC	13.948	Up-regulation
AGC_PKC_PKCh_PRKCE_ST	O14920	IKBKB	Q02156	PRKCE	S335	K337N	337	Missense	proximal	2	no	14.390	7.934	EPSD	TCGA;GDSC;CCLE	13.948	Loss
AGC_PKC_PKCh_PRKCE_ST	O14920	IKBKB	Q02156	PRKCE	T368	P363R	363	Missense	distal	-5	no	15.594	15.576	EPSD	TCGA;COSMIC	13.948	Down-regulation
AGC_PKC_PKCh_PRKCE_ST	O14920	IKBKB	Q02156	PRKCE	T368	P363L	363	Missense	distal	-5	no	15.594	15.589	EPSD	TCGA;COSMIC	13.948	Down-regulation
AGC_PKC_PKCh_PRKCE_ST	O14920	IKBKB	Q02156	PRKCE	S402	E398D	398	Missense	distal	-4	no	14.109	14.131	EPSD	TCGA;COSMIC	13.948	Up-regulation
AGC_PKC_PKCh_PRKCE_ST	O14920	IKBKB	Q02156	PRKCE	S507	W514C	514	Missense	distal	7	no	14.810	16.885	EPSD	TCGA;COSMIC	13.948	Up-regulation
AGC_PKC_PKCh_PRKCE_ST	O14920	IKBKB	Q02156	PRKCE	S507	L511M	511	Missense	distal	4	no	14.810	14.406	EPSD	TCGA	13.948	Down-regulation
AGC_PKC_PKCh_PRKCE_ST	P19429	TNNI3	Q02156	PRKCE	S23	I19T	19	Missense	distal	-4	no	20.306	20.138	EPSD	TCGA;ICGC;COSMIC	13.948	Down-regulation
AGC_PKC_PKCh_PRKCE_ST	P19429	TNNI3	Q02156	PRKCE	S23	Y29H	29	Missense	distal	6	no	20.306	20.819	EPSD	TCGA;ICGC;COSMIC	13.948	Up-regulation
AGC_PKC_PKCh_PRKCE_ST	P19429	TNNI3	Q02156	PRKCE	S23	R21C	21	Missense	proximal	-2	no	20.306	18.803	EPSD	TCGA	13.948	Down-regulation
AGC_PKC_PKCh_PRKCE_ST	P19429	TNNI3	Q02156	PRKCE	S23	R22H	22	Missense	proximal	-1	no	20.306	18.969	EPSD	TCGA;ICGC	13.948	Down-regulation
AGC_PKC_PKCh_PRKCE_ST	P19429	TNNI3	Q02156	PRKCE	S24	I19T	19	Missense	distal	-5	no	17.186	17.162	EPSD	TCGA;ICGC;COSMIC	13.948	Down-regulation
AGC_PKC_PKCh_PRKCE_ST	P19429	TNNI3	Q02156	PRKCE	S24	Y29H	29	Missense	distal	5	no	17.186	17.333	EPSD	TCGA;ICGC;COSMIC	13.948	Up-regulation
AGC_PKC_PKCh_PRKCE_ST	P19429	TNNI3	Q02156	PRKCE	S24	R21C	21	Missense	distal	-3	no	17.186	9.096	EPSD	TCGA	13.948	Loss
AGC_PKC_PKCh_PRKCE_ST	P19429	TNNI3	Q02156	PRKCE	S24	R22H	22	Missense	proximal	-2	no	17.186	14.637	EPSD	TCGA;ICGC	13.948	Down-regulation
AGC_PKC_PKCh_PRKCE_ST	P19429	TNNI3	Q02156	PRKCE	S44	K40R	40	Missense	distal	-4	no	16.546	16.274	PhosphoSitePlus	TCGA;COSMIC	13.948	Down-regulation
AGC_PKC_PKCh_PRKCE_ST	P19429	TNNI3	Q02156	PRKCE	S77	S77N	77	Missense	central	0	yes	23.315	0.000	EPSD	TCGA	13.948	Loss
AGC_PKC_PKCh_PRKCE_ST	P19429	TNNI3	Q02156	PRKCE	T143	R136Q	136	Missense	distal	-7	no	19.722	19.541	EPSD	TCGA;COSMIC	13.948	Down-regulation
AGC_PKC_PKCh_PRKCE_ST	P19429	TNNI3	Q02156	PRKCE	T143	R141W	141	Missense	proximal	-2	no	19.722	16.504	EPSD	TCGA	13.948	Down-regulation
AGC_PKC_PKCh_PRKCE_ST	P19429	TNNI3	Q02156	PRKCE	T143	R145Q	145	Missense	proximal	2	no	19.722	14.490	EPSD	TCGA;COSMIC;GDSC;CCLE	13.948	Down-regulation
AGC_PKC_PKCh_PRKCE_ST	P19429	TNNI3	Q02156	PRKCE	T181	T181P	181	Missense	central	0	yes	19.745	0.000	EPSD	TCGA;COSMIC	13.948	Loss
AGC_PKC_PKCh_PRKCE_ST	P19429	TNNI3	Q02156	PRKCE	T181	E182D	182	Missense	proximal	1	no	19.745	21.130	EPSD	TCGA;COSMIC	13.948	Up-regulation
AGC_PKC_PKCh_PRKCE_ST	P19429	TNNI3	Q02156	PRKCE	T181	K174N	174	Missense	distal	-7	no	19.745	19.719	EPSD	TCGA;COSMIC	13.948	Down-regulation
AGC_PKC_PKCh_PRKCE_ST	P19429	TNNI3	Q02156	PRKCE	T181	R186W	186	Missense	distal	5	no	19.745	20.514	EPSD	TCGA;COSMIC	13.948	Up-regulation
AGC_PKC_PKCh_PRKCE_ST	P15336	ATF2	Q02156	PRKCE	S100	E93Q	93	Missense	distal	-7	no	23.109	23.046	EPSD	TCGA;COSMIC	13.948	Down-regulation
AGC_PKC_PKCh_PRKCE_ST	P15336	ATF2	Q02156	PRKCE	S146	E148K	148	Missense	proximal	2	no	8.844	15.510	EPSD	TCGA;COSMIC	13.948	Gain
AGC_PKC_PKCh_PRKCE_ST	P15336	ATF2	Q02156	PRKCE	T253	G260E	260	Missense	distal	7	no	15.685	16.142	EPSD	TCGA;COSMIC	13.948	Up-regulation
AGC_PKC_PKCh_PRKCE_ST	P15336	ATF2	Q02156	PRKCE	S340	P334A	334	Missense	distal	-6	no	17.489	17.477	EPSD	TCGA;COSMIC	13.948	Down-regulation
AGC_PKC_PKCh_PRKCE_ST	P15336	ATF2	Q02156	PRKCE	S340	T339A	339	Missense	proximal	-1	no	17.489	17.681	EPSD	TCGA;COSMIC	13.948	Up-regulation
AGC_PKC_PKCh_PRKCE_ST	P15336	ATF2	Q02156	PRKCE	S484	A481V	481	Missense	distal	-3	no	14.382	12.235	EPSD	TCGA;COSMIC	13.948	Loss
AGC_PKC_PKCh_PRKCE_ST	P15336	ATF2	Q02156	PRKCE	S484	T478S	478	Missense	distal	-6	no	14.382	14.479	EPSD	TCGA;COSMIC	13.948	Up-regulation
AGC_PKC_PKCh_PRKCE_ST	P15336	ATF2	Q02156	PRKCE	S484	D482Y	482	Missense	proximal	-2	no	14.382	14.004	EPSD	TCGA;COSMIC	13.948	Down-regulation
AGC_PKC_PKCh_PRKCE_ST	P15336	ATF2	Q02156	PRKCE	S498	S500L	500	Missense	proximal	2	no	18.193	16.996	EPSD	TCGA;COSMIC	13.948	Down-regulation
AGC_PKC_PKCh_PRKCE_ST	P15336	ATF2	Q02156	PRKCE	S498	Q499L	499	Missense	proximal	1	no	18.193	19.244	EPSD	TCGA;COSMIC	13.948	Up-regulation
AGC_PKC_PKCh_PRKCE_ST	P15336	ATF2	Q02156	PRKCE	S498	P502L	502	Missense	distal	4	no	18.193	17.691	EPSD	TCGA;COSMIC	13.948	Down-regulation
AGC_PKC_PKCh_PRKCE_ST	P15336	ATF2	Q02156	PRKCE	S498	P502T	502	Missense	distal	4	no	18.193	17.496	EPSD	TCGA;COSMIC	13.948	Down-regulation
AGC_PKC_PKCh_PRKCE_ST	P15336	ATF2	Q02156	PRKCE	S500	S500L	500	Missense	central	0	yes	18.357	0.000	EPSD	TCGA;COSMIC	13.948	Loss
AGC_PKC_PKCh_PRKCE_ST	P15336	ATF2	Q02156	PRKCE	S500	Q499L	499	Missense	proximal	-1	no	18.357	17.913	EPSD	TCGA;COSMIC	13.948	Down-regulation
AGC_PKC_PKCh_PRKCE_ST	P15336	ATF2	Q02156	PRKCE	S500	P502L	502	Missense	proximal	2	no	18.357	16.505	EPSD	TCGA;COSMIC	13.948	Down-regulation
AGC_PKC_PKCh_PRKCE_ST	P15336	ATF2	Q02156	PRKCE	S500	P502T	502	Missense	proximal	2	no	18.357	14.171	EPSD	TCGA;COSMIC	13.948	Down-regulation
AGC_PKC_PKCh_PRKCE_ST	P15336	ATF2	Q02156	PRKCE	S505	P502T	502	Missense	distal	-3	no	10.792	14.303	EPSD	TCGA;COSMIC	13.948	Gain
AGC_PKC_PKCh_PRKCE_ST	O60716	CTNND1	Q02156	PRKCE	T149	T147S	147	Missense	proximal	-2	no	14.978	16.487	EPSD	TCGA;COSMIC	13.948	Up-regulation
AGC_PKC_PKCh_PRKCE_ST	O60716	CTNND1	Q02156	PRKCE	T149	R151Q	151	Missense	proximal	2	no	14.978	9.746	EPSD	TCGA;COSMIC	13.948	Loss
AGC_PKC_PKCh_PRKCE_ST	O60716	CTNND1	Q02156	PRKCE	S225	P222R	222	Missense	distal	-3	no	11.927	20.013	EPSD	TCGA;COSMIC;CCLE	13.948	Gain
AGC_PKC_PKCh_PRKCE_ST	O60716	CTNND1	Q02156	PRKCE	S252	R249W	249	Missense	distal	-3	no	15.323	4.326	EPSD	TCGA;COSMIC	13.948	Loss
AGC_PKC_PKCh_PRKCE_ST	O60716	CTNND1	Q02156	PRKCE	S268	R264Q	264	Missense	distal	-4	no	15.243	15.387	PhosphoSitePlus	TCGA;COSMIC	13.948	Up-regulation
AGC_PKC_PKCh_PRKCE_ST	O60716	CTNND1	Q02156	PRKCE	S268	S269T	269	Missense	proximal	1	no	15.243	14.697	PhosphoSitePlus	TCGA	13.948	Down-regulation
AGC_PKC_PKCh_PRKCE_ST	O60716	CTNND1	Q02156	PRKCE	S268	V265I	265	Missense	distal	-3	no	15.243	17.357	PhosphoSitePlus	TCGA;COSMIC	13.948	Up-regulation
AGC_PKC_PKCh_PRKCE_ST	O60716	CTNND1	Q02156	PRKCE	S268	D271N	271	Missense	distal	3	no	15.243	15.155	PhosphoSitePlus	TCGA;COSMIC	13.948	Down-regulation
AGC_PKC_PKCh_PRKCE_ST	O60716	CTNND1	Q02156	PRKCE	S268	F275L	275	Missense	distal	7	no	15.243	14.445	PhosphoSitePlus	TCGA;COSMIC	13.948	Down-regulation
AGC_PKC_PKCh_PRKCE_ST	O60716	CTNND1	Q02156	PRKCE	S268	R274H	274	Missense	distal	6	no	15.243	15.931	PhosphoSitePlus	TCGA;COSMIC;GDSC;CCLE	13.948	Up-regulation
AGC_PKC_PKCh_PRKCE_ST	O60716	CTNND1	Q02156	PRKCE	S268	R264W	264	Missense	distal	-4	no	15.243	15.796	PhosphoSitePlus	TCGA;COSMIC	13.948	Up-regulation
AGC_PKC_PKCh_PRKCE_ST	O60716	CTNND1	Q02156	PRKCE	S268	V263I	263	Missense	distal	-5	no	15.243	15.275	PhosphoSitePlus	TCGA	13.948	Up-regulation
AGC_PKC_PKCh_PRKCE_ST	O60716	CTNND1	Q02156	PRKCE	S312	R317H	317	Missense	distal	5	no	13.638	14.002	EPSD	TCGA;COSMIC	13.948	Gain
AGC_PKC_PKCh_PRKCE_ST	O60716	CTNND1	Q02156	PRKCE	S320	R315G	315	Missense	distal	-5	no	15.343	15.358	EPSD	TCGA;COSMIC	13.948	Up-regulation
AGC_PKC_PKCh_PRKCE_ST	O60716	CTNND1	Q02156	PRKCE	S320	L318R	318	Missense	proximal	-2	no	15.343	18.447	EPSD	TCGA;COSMIC	13.948	Up-regulation
AGC_PKC_PKCh_PRKCE_ST	O60716	CTNND1	Q02156	PRKCE	S320	R317H	317	Missense	distal	-3	no	15.343	10.123	EPSD	TCGA;COSMIC	13.948	Loss
AGC_PKC_PKCh_PRKCE_ST	O60716	CTNND1	Q02156	PRKCE	S484	I489S	489	Missense	distal	5	no	18.581	18.388	EPSD	TCGA;COSMIC	13.948	Down-regulation
AGC_PKC_PKCh_PRKCE_ST	O60716	CTNND1	Q02156	PRKCE	S484	V490M	490	Missense	distal	6	no	18.581	18.297	EPSD	TCGA;COSMIC	13.948	Down-regulation
AGC_PKC_PKCh_PRKCE_ST	O60716	CTNND1	Q02156	PRKCE	S731	E724K	724	Missense	distal	-7	no	16.625	16.522	EPSD	TCGA;COSMIC	13.948	Down-regulation
AGC_PKC_PKCh_PRKCE_ST	O60716	CTNND1	Q02156	PRKCE	S731	L734P	734	Missense	distal	3	no	16.625	16.823	EPSD	TCGA;COSMIC	13.948	Up-regulation
AGC_PKC_PKCh_PRKCE_ST	O60716	CTNND1	Q02156	PRKCE	S811	I808M	808	Missense	distal	-3	no	17.985	11.962	EPSD	TCGA	13.948	Loss
AGC_PKC_PKCh_PRKCE_ST	O60716	CTNND1	Q02156	PRKCE	S811	R814H	814	Missense	distal	3	no	17.985	17.072	EPSD	TCGA;COSMIC	13.948	Down-regulation
AGC_PKC_PKCh_PRKCE_ST	O60716	CTNND1	Q02156	PRKCE	S811	K810T	810	Missense	proximal	-1	no	17.985	17.479	EPSD	TCGA	13.948	Down-regulation
AGC_PKC_PKCh_PRKCE_ST	P08581	MET	Q02156	PRKCE	S283	S283Y	283	Missense	central	0	yes	16.406	0.000	EPSD	TCGA;ICGC;COSMIC	13.948	Loss
AGC_PKC_PKCh_PRKCE_ST	P08581	MET	Q02156	PRKCE	S283	R277I	277	Missense	distal	-6	no	16.406	16.290	EPSD	TCGA;ICGC;COSMIC	13.948	Down-regulation
AGC_PKC_PKCh_PRKCE_ST	P08581	MET	Q02156	PRKCE	T1257	S1254R	1254	Missense	distal	-3	no	12.165	16.934	EPSD	TCGA;COSMIC	13.948	Gain
AGC_PKC_PKCh_PRKCE_ST	P08581	MET	Q02156	PRKCE	T1261	S1254R	1254	Missense	distal	-7	no	15.563	15.735	EPSD	TCGA;COSMIC	13.948	Up-regulation
STE_STE20_MST_STK3_ST	P17252	PRKCA	Q13188	STK3	T108	I106F	106	Missense	proximal	-2	no	59.282	59.231	EPSD	TCGA;ICGC;COSMIC	55.172	Down-regulation
STE_STE20_MST_STK3_ST	P17252	PRKCA	Q13188	STK3	T108	C115G	115	Missense	distal	7	no	59.282	58.104	EPSD	TCGA;ICGC;COSMIC	55.172	Down-regulation
STE_STE20_MST_STK3_ST	P17252	PRKCA	Q13188	STK3	T108	G110R	110	Missense	proximal	2	no	59.282	59.227	EPSD	TCGA;ICGC;COSMIC	55.172	Down-regulation
STE_STE20_MST_STK3_ST	P17252	PRKCA	Q13188	STK3	T176	E171D	171	Missense	distal	-5	no	60.683	49.184	EPSD	TCGA;ICGC;COSMIC	55.172	Loss
STE_STE20_MST_STK3_ST	P17252	PRKCA	Q13188	STK3	T218	S217C	217	Missense	proximal	-1	no	58.570	61.831	EPSD	TCGA;ICGC;COSMIC	55.172	Up-regulation
STE_STE20_MST_STK3_ST	P17252	PRKCA	Q13188	STK3	T218	S217F	217	Missense	proximal	-1	no	58.570	62.867	EPSD	TCGA;ICGC;COSMIC	55.172	Up-regulation
STE_STE20_MST_STK3_ST	P17252	PRKCA	Q13188	STK3	T218	R216H	216	Missense	proximal	-2	no	58.570	57.637	EPSD	TCGA;ICGC;COSMIC	55.172	Down-regulation
STE_STE20_MST_STK3_ST	P17252	PRKCA	Q13188	STK3	S226	T228I	228	Missense	proximal	2	no	93.402	93.754	PhosphoSitePlus;EPSD	TCGA;ICGC;COSMIC	55.172	Up-regulation
STE_STE20_MST_STK3_ST	P17252	PRKCA	Q13188	STK3	S226	P233H	233	Missense	distal	7	no	93.402	92.363	PhosphoSitePlus;EPSD	TCGA;ICGC	55.172	Down-regulation
STE_STE20_MST_STK3_ST	P17252	PRKCA	Q13188	STK3	T228	S234L	234	Missense	distal	6	no	111.878	104.043	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	55.172	Down-regulation
STE_STE20_MST_STK3_ST	P17252	PRKCA	Q13188	STK3	T228	T228I	228	Missense	central	0	yes	111.878	0.000	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	55.172	Loss
STE_STE20_MST_STK3_ST	P17252	PRKCA	Q13188	STK3	T228	P233H	233	Missense	distal	5	no	111.878	113.217	EPSD;PhosphoSitePlus	TCGA;ICGC	55.172	Up-regulation
STE_STE20_MST_STK3_ST	P17252	PRKCA	Q13188	STK3	S258	G257V	257	Missense	proximal	-1	no	57.560	56.598	EPSD	TCGA;ICGC;COSMIC	55.172	Down-regulation
STE_STE20_MST_STK3_ST	P17252	PRKCA	Q13188	STK3	S258	S260F	260	Missense	proximal	2	no	57.560	58.649	EPSD	TCGA;ICGC;COSMIC	55.172	Up-regulation
STE_STE20_MST_STK3_ST	P17252	PRKCA	Q13188	STK3	T497	G500R	500	Missense	distal	3	no	70.838	69.032	EPSD	TCGA;ICGC;COSMIC	55.172	Down-regulation
STE_STE20_MST_STK3_ST	P17252	PRKCA	Q13188	STK3	T497	G500E	500	Missense	distal	3	no	70.838	67.183	EPSD	TCGA;ICGC;COSMIC	55.172	Down-regulation
STE_STE20_MST_STK3_ST	P17252	PRKCA	Q13188	STK3	T497	D503G	503	Missense	distal	6	no	70.838	70.821	EPSD	TCGA;ICGC;COSMIC	55.172	Down-regulation
STE_STE20_MST_STK3_ST	Q7L9L4	MOB1B	Q13188	STK3	T12	K16T	16	Missense	distal	4	no	96.089	95.762	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	55.172	Down-regulation
STE_STE20_MST_STK3_ST	Q9H4B6	SAV1	Q13188	STK3	T26	R31W	31	Missense	distal	5	no	96.976	97.607	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	55.172	Up-regulation
STE_STE20_MST_STK3_ST	Q9H4B6	SAV1	Q13188	STK3	S27	R31W	31	Missense	distal	4	no	81.901	83.256	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	55.172	Up-regulation
STE_STE20_MST_STK3_ST	Q9H4B6	SAV1	Q13188	STK3	S36	P35L	35	Missense	proximal	-1	no	94.363	94.061	PhosphoSitePlus;EPSD	TCGA;ICGC;COSMIC	55.172	Down-regulation
STE_STE20_MST_STK3_ST	Q9H4B6	SAV1	Q13188	STK3	S36	R31W	31	Missense	distal	-5	no	94.363	90.162	PhosphoSitePlus;EPSD	TCGA;ICGC;COSMIC	55.172	Down-regulation
STE_STE20_MST_STK3_ST	Q9H4B6	SAV1	Q13188	STK3	S269	P268T	268	Missense	proximal	-1	no	93.324	92.892	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	55.172	Down-regulation
STE_STE20_MST_STK3_ST	Q9H8S9	MOB1A	Q13188	STK3	T12	K16N	16	Missense	distal	4	no	101.150	101.069	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	55.172	Down-regulation
STE_STE20_MST_STK3_ST	Q9H8S9	MOB1A	Q13188	STK3	T12	K14E	14	Missense	proximal	2	no	101.150	100.954	EPSD;PhosphoSitePlus	TCGA;ICGC	55.172	Down-regulation
STE_STE20_MST_STK3_ST	Q9H8S9	MOB1A	Q13188	STK3	T35	L41V	41	Missense	distal	6	no	95.972	96.830	PhosphoSitePlus;EPSD	TCGA;ICGC;COSMIC	55.172	Up-regulation
STE_STE20_MST_STK3_ST	P51955	NEK2	Q13188	STK3	T175	T170M	170	Missense	distal	-5	no	62.472	61.073	EPSD	TCGA	55.172	Down-regulation
STE_STE20_MST_STK3_ST	P51955	NEK2	Q13188	STK3	S356	N350H	350	Missense	distal	-6	no	91.920	90.305	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	55.172	Down-regulation
STE_STE20_MST_STK3_ST	P51955	NEK2	Q13188	STK3	S356	E360K	360	Missense	distal	4	no	91.920	93.297	EPSD;PhosphoSitePlus	TCGA;ICGC	55.172	Up-regulation
STE_STE20_MST_STK3_ST	P51955	NEK2	Q13188	STK3	S356	L351M	351	Missense	distal	-5	no	91.920	87.989	EPSD;PhosphoSitePlus	TCGA;COSMIC	55.172	Down-regulation
STE_STE20_MST_STK3_ST	P51955	NEK2	Q13188	STK3	S365	E360K	360	Missense	distal	-5	no	107.348	103.994	EPSD;PhosphoSitePlus	TCGA;ICGC	55.172	Down-regulation
STE_STE20_MST_STK3_ST	P51955	NEK2	Q13188	STK3	T405	S402G	402	Missense	distal	-3	no	57.833	50.847	EPSD	TCGA;COSMIC	55.172	Loss
STE_STE20_MST_STK3_ST	P51955	NEK2	Q13188	STK3	T405	S408P	408	Missense	distal	3	no	57.833	60.256	EPSD	TCGA	55.172	Up-regulation
STE_STE20_MST_STK3_ST	P51955	NEK2	Q13188	STK3	S406	S402G	402	Missense	distal	-4	no	92.917	95.640	PhosphoSitePlus;EPSD	TCGA;COSMIC	55.172	Up-regulation
STE_STE20_MST_STK3_ST	P51955	NEK2	Q13188	STK3	S406	S408P	408	Missense	proximal	2	no	92.917	93.647	PhosphoSitePlus;EPSD	TCGA	55.172	Up-regulation
STE_STE20_MST_STK3_ST	P51955	NEK2	Q13188	STK3	S438	G443C	443	Missense	distal	5	no	73.331	74.208	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	55.172	Up-regulation
STE_STE20_MST_STK3_ST	P51955	NEK2	Q13188	STK3	S438	N433K	433	Missense	distal	-5	no	73.331	74.353	EPSD;PhosphoSitePlus	TCGA;COSMIC	55.172	Up-regulation
STE_STE20_MST_STK3_ST	O95835	LATS1	Q13188	STK3	S27	R28W	28	Missense	proximal	1	no	56.802	51.244	EPSD	TCGA	55.172	Loss
STE_STE20_MST_STK3_ST	O95835	LATS1	Q13188	STK3	S27	R28Q	28	Missense	proximal	1	no	56.802	62.706	EPSD	TCGA;ICGC;COSMIC	55.172	Up-regulation
STE_STE20_MST_STK3_ST	O95835	LATS1	Q13188	STK3	S27	V25F	25	Missense	proximal	-2	no	56.802	54.745	EPSD	TCGA;ICGC;COSMIC	55.172	Loss
STE_STE20_MST_STK3_ST	O95835	LATS1	Q13188	STK3	S207	Q208L	208	Missense	proximal	1	no	54.787	76.799	EPSD	TCGA;ICGC;COSMIC	55.172	Gain
STE_STE20_MST_STK3_ST	O95835	LATS1	Q13188	STK3	S404	V411A	411	Missense	distal	7	no	61.600	62.314	EPSD	TCGA;ICGC;COSMIC	55.172	Up-regulation
STE_STE20_MST_STK3_ST	O95835	LATS1	Q13188	STK3	S872	D871Y	871	Missense	proximal	-1	no	89.781	89.451	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	55.172	Down-regulation
STE_STE20_MST_STK3_ST	O95835	LATS1	Q13188	STK3	S883	P882H	882	Missense	proximal	-1	no	55.923	57.072	EPSD	TCGA;ICGC;COSMIC	55.172	Up-regulation
STE_STE20_MST_STK3_ST	O95835	LATS1	Q13188	STK3	S883	S884R	884	Missense	proximal	1	no	55.923	41.185	EPSD	TCGA;ICGC;COSMIC	55.172	Loss
STE_STE20_MST_STK3_ST	O95835	LATS1	Q13188	STK3	S909	L910S	910	Missense	proximal	1	no	108.035	94.857	PhosphoSitePlus;EPSD	TCGA;ICGC;COSMIC	55.172	Down-regulation
STE_STE20_MST_STK3_ST	O95835	LATS1	Q13188	STK3	T1012	H1007Y	1007	Missense	distal	-5	no	96.824	91.673	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	55.172	Down-regulation
STE_STE20_MST_STK3_ST	O95835	LATS1	Q13188	STK3	T1012	F1015L	1015	Missense	distal	3	no	96.824	95.305	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	55.172	Down-regulation
STE_STE20_MST_STK3_ST	O95835	LATS1	Q13188	STK3	T1060	V1057A	1057	Missense	distal	-3	no	92.256	94.857	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	55.172	Up-regulation
STE_STE20_MST_STK3_ST	O95835	LATS1	Q13188	STK3	T1060	E1055A	1055	Missense	distal	-5	no	92.256	83.405	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	55.172	Down-regulation
STE_STE20_MST_STK3_ST	O95835	LATS1	Q13188	STK3	T1079	D1086V	1086	Missense	distal	7	no	94.072	91.708	EPSD;PhosphoSitePlus	TCGA	55.172	Down-regulation
STE_STE20_MST_STK3_ST	O95835	LATS1	Q13188	STK3	T1079	R1082K	1082	Missense	distal	3	no	94.072	92.907	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC;GDSC	55.172	Down-regulation
STE_STE20_MST_STK3_ST	O95835	LATS1	Q13188	STK3	T1079	D1086Y	1086	Missense	distal	7	no	94.072	92.944	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	55.172	Down-regulation
STE_STE20_MST_STK3_ST	O95835	LATS1	Q13188	STK3	T1079	R1081Q	1081	Missense	proximal	2	no	94.072	93.085	EPSD;PhosphoSitePlus	TCGA;ICGC	55.172	Down-regulation
STE_STE20_MST_STK3_ST	P46937	YAP1	Q13188	STK3	S105	R106Q	106	Missense	proximal	1	no	53.818	59.722	EPSD	TCGA;ICGC;COSMIC;CCLE	55.172	Gain
STE_STE20_MST_STK3_ST	P46937	YAP1	Q13188	STK3	S127	Q121H	121	Missense	distal	-6	no	88.207	84.674	PhosphoSitePlus	TCGA;ICGC;COSMIC	55.172	Down-regulation
STE_STE20_MST_STK3_ST	P46937	YAP1	Q13188	STK3	S127	P129S	129	Missense	proximal	2	no	88.207	87.476	PhosphoSitePlus	TCGA;ICGC;COSMIC	55.172	Down-regulation
STE_STE20_MST_STK3_ST	P46937	YAP1	Q13188	STK3	S127	R124P	124	Missense	distal	-3	no	88.207	87.291	PhosphoSitePlus	TCGA;ICGC;COSMIC	55.172	Down-regulation
STE_STE20_MST_STK3_ST	P46937	YAP1	Q13188	STK3	S127	R124Q	124	Missense	distal	-3	no	88.207	92.453	PhosphoSitePlus	TCGA;ICGC;COSMIC	55.172	Up-regulation
STE_STE20_MST_STK3_ST	P46937	YAP1	Q13188	STK3	S131	G135E	135	Missense	distal	4	no	59.720	56.640	EPSD	TCGA;ICGC;COSMIC	55.172	Down-regulation
STE_STE20_MST_STK3_ST	P46937	YAP1	Q13188	STK3	S131	P129S	129	Missense	proximal	-2	no	59.720	59.743	EPSD	TCGA;ICGC;COSMIC	55.172	Up-regulation
STE_STE20_MST_STK3_ST	P46937	YAP1	Q13188	STK3	S131	S138F	138	Missense	distal	7	no	59.720	60.722	EPSD	TCGA;ICGC;COSMIC	55.172	Up-regulation
STE_STE20_MST_STK3_ST	P46937	YAP1	Q13188	STK3	S131	R124P	124	Missense	distal	-7	no	59.720	60.471	EPSD	TCGA;ICGC;COSMIC	55.172	Up-regulation
STE_STE20_MST_STK3_ST	P46937	YAP1	Q13188	STK3	S131	R124Q	124	Missense	distal	-7	no	59.720	59.529	EPSD	TCGA;ICGC;COSMIC	55.172	Down-regulation
STE_STE20_MST_STK3_ST	P46937	YAP1	Q13188	STK3	S274	S276N	276	Missense	proximal	2	no	56.361	57.045	EPSD	TCGA;ICGC	55.172	Up-regulation
STE_STE20_MST_STK3_ST	P46937	YAP1	Q13188	STK3	S274	A268G	268	Missense	distal	-6	no	56.361	53.069	EPSD	TCGA;ICGC;COSMIC	55.172	Loss
STE_STE20_MST_STK3_ST	P46937	YAP1	Q13188	STK3	S274	Q275H	275	Missense	proximal	1	no	56.361	44.879	EPSD	TCGA;ICGC;COSMIC	55.172	Loss
STE_STE20_MST_STK3_ST	P46937	YAP1	Q13188	STK3	T361	S366C	366	Missense	distal	5	no	59.163	62.466	EPSD	TCGA	55.172	Up-regulation
Atypical_PIKK_ATR_ATR_ST	O60934	NBN	Q13535	ATR	S278	D284G	284	Missense	distal	6	no	15.706	15.653	EPSD	TCGA;COSMIC	10.658	Down-regulation
Atypical_PIKK_ATR_ATR_ST	O60934	NBN	Q13535	ATR	S278	T276A	276	Missense	proximal	-2	no	15.706	16.180	EPSD	TCGA	10.658	Up-regulation
Atypical_PIKK_ATR_ATR_ST	O60934	NBN	Q13535	ATR	T337	P338L	338	Missense	proximal	1	no	11.429	10.863	EPSD	TCGA;COSMIC	10.658	Down-regulation
Atypical_PIKK_ATR_ATR_ST	O60934	NBN	Q13535	ATR	T337	T337N	337	Missense	central	0	yes	11.429	0.000	EPSD	TCGA;COSMIC	10.658	Loss
Atypical_PIKK_ATR_ATR_ST	O60934	NBN	Q13535	ATR	T337	T337I	337	Missense	central	0	yes	11.429	0.000	EPSD	TCGA;COSMIC	10.658	Loss
Atypical_PIKK_ATR_ATR_ST	O60934	NBN	Q13535	ATR	S343	P338L	338	Missense	distal	-5	no	16.611	16.764	PhosphoSitePlus;EPSD	TCGA;COSMIC	10.658	Up-regulation
Atypical_PIKK_ATR_ATR_ST	O60934	NBN	Q13535	ATR	S343	T337N	337	Missense	distal	-6	no	16.611	16.591	PhosphoSitePlus;EPSD	TCGA;COSMIC	10.658	Down-regulation
Atypical_PIKK_ATR_ATR_ST	O60934	NBN	Q13535	ATR	S343	T337I	337	Missense	distal	-6	no	16.611	16.609	PhosphoSitePlus;EPSD	TCGA;COSMIC	10.658	Down-regulation
Atypical_PIKK_ATR_ATR_ST	O60934	NBN	Q13535	ATR	S397	K392Q	392	Missense	distal	-5	no	13.700	13.792	EPSD	TCGA;COSMIC	10.658	Up-regulation
Atypical_PIKK_ATR_ATR_ST	O60934	NBN	Q13535	ATR	S447	S454F	454	Missense	distal	7	no	12.757	12.818	EPSD	TCGA;COSMIC	10.658	Up-regulation
Atypical_PIKK_ATR_ATR_ST	O60934	NBN	Q13535	ATR	S447	S447Y	447	Missense	central	0	yes	12.757	0.000	EPSD	TCGA;COSMIC	10.658	Loss
Atypical_PIKK_ATR_ATR_ST	O60934	NBN	Q13535	ATR	T493	S499L	499	Missense	distal	6	no	13.766	13.541	EPSD	TCGA;COSMIC	10.658	Down-regulation
Atypical_PIKK_ATR_ATR_ST	O60934	NBN	Q13535	ATR	S509	E510Q	510	Missense	proximal	1	no	9.557	15.477	EPSD	TCGA;COSMIC	10.658	Gain
Atypical_PIKK_ATR_ATR_ST	O60934	NBN	Q13535	ATR	S615	E610K	610	Missense	distal	-5	no	17.909	17.990	EPSD;PhosphoSitePlus	TCGA;COSMIC	10.658	Up-regulation
Atypical_PIKK_ATR_ATR_ST	O60934	NBN	Q13535	ATR	S615	E619K	619	Missense	distal	4	no	17.909	18.020	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	10.658	Up-regulation
Atypical_PIKK_ATR_ATR_ST	O60934	NBN	Q13535	ATR	S738	A740V	740	Missense	proximal	2	no	10.457	10.947	EPSD	TCGA;COSMIC	10.658	Gain
Atypical_PIKK_ATR_ATR_ST	P78527	PRKDC	Q13535	ATR	S237	F234L	234	Missense	distal	-3	no	13.188	12.901	EPSD	TCGA;ICGC;COSMIC	10.658	Down-regulation
Atypical_PIKK_ATR_ATR_ST	P78527	PRKDC	Q13535	ATR	S237	C232W	232	Missense	distal	-5	no	13.188	13.212	EPSD	TCGA;ICGC;COSMIC	10.658	Up-regulation
Atypical_PIKK_ATR_ATR_ST	P78527	PRKDC	Q13535	ATR	S237	Q243H	243	Missense	distal	6	no	13.188	12.995	EPSD	TCGA;ICGC	10.658	Down-regulation
Atypical_PIKK_ATR_ATR_ST	P78527	PRKDC	Q13535	ATR	S245	Q243H	243	Missense	proximal	-2	no	11.126	10.759	EPSD	TCGA;ICGC	10.658	Down-regulation
Atypical_PIKK_ATR_ATR_ST	P78527	PRKDC	Q13535	ATR	S318	L320V	320	Missense	proximal	2	no	12.371	13.973	EPSD	TCGA;ICGC;COSMIC	10.658	Up-regulation
Atypical_PIKK_ATR_ATR_ST	P78527	PRKDC	Q13535	ATR	S318	L313F	313	Missense	distal	-5	no	12.371	12.415	EPSD	TCGA;ICGC;COSMIC	10.658	Up-regulation
Atypical_PIKK_ATR_ATR_ST	P78527	PRKDC	Q13535	ATR	S922	E916Q	916	Missense	distal	-6	no	11.243	11.262	EPSD	TCGA;ICGC;COSMIC	10.658	Up-regulation
Atypical_PIKK_ATR_ATR_ST	P78527	PRKDC	Q13535	ATR	S936	A930V	930	Missense	distal	-6	no	11.550	11.520	EPSD	TCGA;ICGC;COSMIC	10.658	Down-regulation
Atypical_PIKK_ATR_ATR_ST	P78527	PRKDC	Q13535	ATR	S2672	S2674F	2674	Missense	proximal	2	no	11.048	8.360	EPSD	TCGA;ICGC	10.658	Loss
Atypical_PIKK_ATR_ATR_ST	P78527	PRKDC	Q13535	ATR	S3313	N3310S	3310	Missense	distal	-3	no	11.310	10.225	EPSD	TCGA;ICGC;COSMIC	10.658	Loss
Atypical_PIKK_ATR_ATR_ST	P78527	PRKDC	Q13535	ATR	T3811	L3815P	3815	Missense	distal	4	no	10.851	10.701	EPSD	TCGA;ICGC	10.658	Down-regulation
Atypical_PIKK_ATR_ATR_ST	P78527	PRKDC	Q13535	ATR	T3819	L3815P	3815	Missense	distal	-4	no	9.965	11.165	EPSD	TCGA;ICGC	10.658	Gain
Atypical_PIKK_ATR_ATR_ST	P78527	PRKDC	Q13535	ATR	S3821	L3815P	3815	Missense	distal	-6	no	14.825	14.761	EPSD	TCGA;ICGC	10.658	Down-regulation
Atypical_PIKK_ATR_ATR_ST	Q99708	RBBP8	Q13535	ATR	S10	S13C	13	Missense	distal	3	no	11.057	10.755	EPSD	TCGA;ICGC;COSMIC	10.658	Down-regulation
Atypical_PIKK_ATR_ATR_ST	Q99708	RBBP8	Q13535	ATR	S10	N12K	12	Missense	proximal	2	no	11.057	10.863	EPSD	TCGA;ICGC;COSMIC	10.658	Down-regulation
Atypical_PIKK_ATR_ATR_ST	Q99708	RBBP8	Q13535	ATR	S10	A14V	14	Missense	distal	4	no	11.057	10.918	EPSD	TCGA;ICGC;COSMIC	10.658	Down-regulation
Atypical_PIKK_ATR_ATR_ST	Q99708	RBBP8	Q13535	ATR	T16	S13C	13	Missense	distal	-3	no	10.727	11.138	EPSD	TCGA;ICGC;COSMIC	10.658	Up-regulation
Atypical_PIKK_ATR_ATR_ST	Q99708	RBBP8	Q13535	ATR	T16	N12K	12	Missense	distal	-4	no	10.727	11.108	EPSD	TCGA;ICGC;COSMIC	10.658	Up-regulation
Atypical_PIKK_ATR_ATR_ST	Q99708	RBBP8	Q13535	ATR	T16	A14V	14	Missense	proximal	-2	no	10.727	10.208	EPSD	TCGA;ICGC;COSMIC	10.658	Loss
Atypical_PIKK_ATR_ATR_ST	Q99708	RBBP8	Q13535	ATR	T241	P246L	246	Missense	distal	5	no	11.558	11.553	EPSD	TCGA;ICGC;COSMIC	10.658	Down-regulation
Atypical_PIKK_ATR_ATR_ST	Q99708	RBBP8	Q13535	ATR	T271	E267K	267	Missense	distal	-4	no	13.320	12.909	EPSD	TCGA;ICGC;COSMIC	10.658	Down-regulation
Atypical_PIKK_ATR_ATR_ST	Q99708	RBBP8	Q13535	ATR	T271	M275L	275	Missense	distal	4	no	13.320	14.002	EPSD	TCGA;ICGC;COSMIC	10.658	Up-regulation
Atypical_PIKK_ATR_ATR_ST	Q99708	RBBP8	Q13535	ATR	T271	P274L	274	Missense	distal	3	no	13.320	12.717	EPSD	TCGA;ICGC;COSMIC	10.658	Down-regulation
Atypical_PIKK_ATR_ATR_ST	Q99708	RBBP8	Q13535	ATR	S345	S347F	347	Missense	proximal	2	no	12.001	9.313	EPSD	TCGA;ICGC;COSMIC	10.658	Loss
Atypical_PIKK_ATR_ATR_ST	Q99708	RBBP8	Q13535	ATR	S439	L437M	437	Missense	proximal	-2	no	13.000	12.667	EPSD	TCGA;ICGC;COSMIC	10.658	Down-regulation
Atypical_PIKK_ATR_ATR_ST	Q99708	RBBP8	Q13535	ATR	S555	E557V	557	Missense	proximal	2	no	15.106	14.674	EPSD	TCGA;ICGC;COSMIC	10.658	Down-regulation
Atypical_PIKK_ATR_ATR_ST	Q99708	RBBP8	Q13535	ATR	S593	P587H	587	Missense	distal	-6	no	11.000	11.043	EPSD	TCGA;ICGC	10.658	Up-regulation
Atypical_PIKK_ATR_ATR_ST	Q99708	RBBP8	Q13535	ATR	S593	E597D	597	Missense	distal	4	no	11.000	11.190	EPSD	TCGA;ICGC;COSMIC;GDSC;CCLE	10.658	Up-regulation
Atypical_PIKK_ATR_ATR_ST	Q99708	RBBP8	Q13535	ATR	S593	E597G	597	Missense	distal	4	no	11.000	12.011	EPSD	TCGA;ICGC;COSMIC	10.658	Up-regulation
Atypical_PIKK_ATR_ATR_ST	Q99708	RBBP8	Q13535	ATR	T596	E597D	597	Missense	proximal	1	no	11.187	11.693	EPSD	TCGA;ICGC;COSMIC;GDSC;CCLE	10.658	Up-regulation
Atypical_PIKK_ATR_ATR_ST	Q99708	RBBP8	Q13535	ATR	T596	E597G	597	Missense	proximal	1	no	11.187	8.163	EPSD	TCGA;ICGC;COSMIC	10.658	Loss
Atypical_PIKK_ATR_ATR_ST	Q99708	RBBP8	Q13535	ATR	S664	V670I	670	Missense	distal	6	no	11.369	11.209	EPSD	TCGA;ICGC	10.658	Down-regulation
Atypical_PIKK_ATR_ATR_ST	Q99708	RBBP8	Q13535	ATR	S664	D658Y	658	Missense	distal	-6	no	11.369	11.479	EPSD	TCGA;ICGC;COSMIC	10.658	Up-regulation
Atypical_PIKK_ATR_ATR_ST	Q99708	RBBP8	Q13535	ATR	S745	E751Q	751	Missense	distal	6	no	12.813	12.599	EPSD	TCGA;COSMIC	10.658	Down-regulation
Atypical_PIKK_ATR_ATR_ST	Q99708	RBBP8	Q13535	ATR	S745	E752Q	752	Missense	distal	7	no	12.813	12.873	EPSD	TCGA;COSMIC;GDSC;CCLE	10.658	Up-regulation
Atypical_PIKK_ATR_ATR_ST	Q99708	RBBP8	Q13535	ATR	S789	H795D	795	Missense	distal	6	no	12.054	12.186	EPSD	TCGA;ICGC;COSMIC	10.658	Up-regulation
Atypical_PIKK_ATR_ATR_ST	Q99708	RBBP8	Q13535	ATR	T859	V854A	854	Missense	distal	-5	no	15.375	15.372	PhosphoSitePlus	TCGA;ICGC;COSMIC	10.658	Down-regulation
Atypical_PIKK_ATR_ATR_ST	Q99708	RBBP8	Q13535	ATR	T859	E864K	864	Missense	distal	5	no	15.375	15.384	PhosphoSitePlus	TCGA;COSMIC	10.658	Up-regulation
Atypical_PIKK_ATR_ATR_ST	Q99708	RBBP8	Q13535	ATR	T859	M863L	863	Missense	distal	4	no	15.375	16.057	PhosphoSitePlus	TCGA;ICGC;COSMIC	10.658	Up-regulation
Atypical_PIKK_ATR_ATR_ST	Q99708	RBBP8	Q13535	ATR	T859	M863I	863	Missense	distal	4	no	15.375	16.502	PhosphoSitePlus	TCGA;COSMIC	10.658	Up-regulation
Atypical_PIKK_ATR_ATR_ST	Q9UPV0	CEP164	Q13535	ATR	S186	G180R	180	Missense	distal	-6	no	16.460	16.512	PhosphoSitePlus	TCGA;ICGC;COSMIC	10.658	Up-regulation
Atypical_PIKK_ATR_ATR_ST	Q9UPV0	CEP164	Q13535	ATR	S186	L182F	182	Missense	distal	-4	no	16.460	17.051	PhosphoSitePlus	TCGA;ICGC	10.658	Up-regulation
Atypical_PIKK_ATR_ATR_ST	Q9UPV0	CEP164	Q13535	ATR	S273	G277S	277	Missense	distal	4	no	12.782	12.013	EPSD	TCGA;ICGC;COSMIC	10.658	Down-regulation
Atypical_PIKK_ATR_ATR_ST	Q9UPV0	CEP164	Q13535	ATR	S273	K266E	266	Missense	distal	-7	no	12.782	12.799	EPSD	TCGA;ICGC;COSMIC	10.658	Up-regulation
Atypical_PIKK_ATR_ATR_ST	Q9UPV0	CEP164	Q13535	ATR	S273	T280A	280	Missense	distal	7	no	12.782	12.681	EPSD	TCGA;ICGC	10.658	Down-regulation
Atypical_PIKK_ATR_ATR_ST	Q9UPV0	CEP164	Q13535	ATR	S294	S294I	294	Missense	central	0	yes	10.742	0.000	EPSD	TCGA;ICGC	10.658	Loss
Atypical_PIKK_ATR_ATR_ST	Q9UPV0	CEP164	Q13535	ATR	S319	N326Y	326	Missense	distal	7	no	10.968	10.771	EPSD	TCGA;ICGC;COSMIC	10.658	Down-regulation
Atypical_PIKK_ATR_ATR_ST	Q9UPV0	CEP164	Q13535	ATR	S319	K318N	318	Missense	proximal	-1	no	10.968	11.552	EPSD	TCGA;ICGC;COSMIC	10.658	Up-regulation
Atypical_PIKK_ATR_ATR_ST	Q9UPV0	CEP164	Q13535	ATR	S319	P321S	321	Missense	proximal	2	no	10.968	10.652	EPSD	TCGA;ICGC;COSMIC	10.658	Loss
Atypical_PIKK_ATR_ATR_ST	Q9UPV0	CEP164	Q13535	ATR	S383	Q384R	384	Missense	proximal	1	no	14.812	7.816	EPSD	TCGA;ICGC;COSMIC	10.658	Loss
Atypical_PIKK_ATR_ATR_ST	Q9UPV0	CEP164	Q13535	ATR	S455	S461N	461	Missense	distal	6	no	13.687	13.801	EPSD	TCGA;ICGC	10.658	Up-regulation
Atypical_PIKK_ATR_ATR_ST	Q9UPV0	CEP164	Q13535	ATR	S472	S472F	472	Missense	central	0	yes	13.499	0.000	EPSD	TCGA;ICGC;COSMIC	10.658	Loss
Atypical_PIKK_ATR_ATR_ST	Q9UPV0	CEP164	Q13535	ATR	S483	R486H	486	Missense	distal	3	no	10.541	10.949	EPSD	TCGA;ICGC;GDSC;CCLE	10.658	Gain
Atypical_PIKK_ATR_ATR_ST	Q9UPV0	CEP164	Q13535	ATR	S566	A564V	564	Missense	proximal	-2	no	10.902	10.382	EPSD	TCGA;ICGC;COSMIC	10.658	Loss
Atypical_PIKK_ATR_ATR_ST	Q9UPV0	CEP164	Q13535	ATR	S566	V563L	563	Missense	distal	-3	no	10.902	11.033	EPSD	TCGA;ICGC;COSMIC	10.658	Up-regulation
Atypical_PIKK_ATR_ATR_ST	Q9UPV0	CEP164	Q13535	ATR	S566	K562N	562	Missense	distal	-4	no	10.902	10.521	EPSD	TCGA;ICGC;COSMIC	10.658	Loss
Atypical_PIKK_ATR_ATR_ST	Q9UPV0	CEP164	Q13535	ATR	S566	P573S	573	Missense	distal	7	no	10.902	10.739	EPSD	TCGA;ICGC;COSMIC	10.658	Down-regulation
Atypical_PIKK_ATR_ATR_ST	Q9UPV0	CEP164	Q13535	ATR	S572	P573S	573	Missense	proximal	1	no	10.740	9.631	EPSD	TCGA;ICGC;COSMIC	10.658	Loss
Atypical_PIKK_ATR_ATR_ST	Q9UPV0	CEP164	Q13535	ATR	S572	T578R	578	Missense	distal	6	no	10.740	10.391	EPSD	TCGA;ICGC;COSMIC	10.658	Loss
Atypical_PIKK_ATR_ATR_ST	Q9UPV0	CEP164	Q13535	ATR	S572	R576Q	576	Missense	distal	4	no	10.740	10.574	EPSD	TCGA;ICGC	10.658	Loss
Atypical_PIKK_ATR_ATR_ST	Q9UPV0	CEP164	Q13535	ATR	S646	R648M	648	Missense	proximal	2	no	11.262	11.943	EPSD	TCGA;ICGC;COSMIC	10.658	Up-regulation
Atypical_PIKK_ATR_ATR_ST	Q9UPV0	CEP164	Q13535	ATR	S646	S646F	646	Missense	central	0	yes	11.262	0.000	EPSD	TCGA;ICGC;COSMIC	10.658	Loss
Atypical_PIKK_ATR_ATR_ST	Q9UPV0	CEP164	Q13535	ATR	S1013	A1020S	1020	Missense	distal	7	no	11.284	11.214	EPSD	TCGA;ICGC;COSMIC	10.658	Down-regulation
Atypical_PIKK_ATR_ATR_ST	Q9UPV0	CEP164	Q13535	ATR	S1013	R1007H	1007	Missense	distal	-6	no	11.284	11.290	EPSD	TCGA;ICGC;COSMIC	10.658	Up-regulation
Atypical_PIKK_ATR_ATR_ST	Q9UPV0	CEP164	Q13535	ATR	S1022	A1020S	1020	Missense	proximal	-2	no	12.486	11.711	EPSD	TCGA;ICGC;COSMIC	10.658	Down-regulation
Atypical_PIKK_ATR_ATR_ST	Q9UPV0	CEP164	Q13535	ATR	S1031	K1038N	1038	Missense	distal	7	no	12.946	13.217	EPSD	TCGA;ICGC	10.658	Up-regulation
Atypical_PIKK_ATR_ATR_ST	Q9UPV0	CEP164	Q13535	ATR	S1083	D1088E	1088	Missense	distal	5	no	12.906	12.891	EPSD	TCGA;ICGC;COSMIC	10.658	Down-regulation
Atypical_PIKK_ATR_ATR_ST	Q9UPV0	CEP164	Q13535	ATR	S1083	E1077D	1077	Missense	distal	-6	no	12.906	12.913	EPSD	TCGA;ICGC	10.658	Up-regulation
Atypical_PIKK_ATR_ATR_ST	Q9UPV0	CEP164	Q13535	ATR	S1273	S1276I	1276	Missense	distal	3	no	12.654	12.663	EPSD	TCGA;ICGC;COSMIC	10.658	Up-regulation
Atypical_PIKK_ATR_ATR_ST	Q9UPV0	CEP164	Q13535	ATR	T1441	S1443G	1443	Missense	proximal	2	no	11.043	11.982	EPSD	TCGA;ICGC	10.658	Up-regulation
Atypical_PIKK_ATR_ATR_ST	Q9UPV0	CEP164	Q13535	ATR	S1443	S1443G	1443	Missense	central	0	yes	11.513	0.000	EPSD	TCGA;ICGC	10.658	Loss
Atypical_PIKK_ATR_ATR_ST	Q8WXE1	ATRIP	Q13535	ATR	S72	A77S	77	Missense	distal	5	no	15.127	15.115	EPSD;PhosphoSitePlus	TCGA	10.658	Down-regulation
Atypical_PIKK_ATR_ATR_ST	Q8WXE1	ATRIP	Q13535	ATR	T307	S310F	310	Missense	distal	3	no	14.734	13.703	EPSD	TCGA;ICGC;COSMIC;GDSC;CCLE	10.658	Down-regulation
Atypical_PIKK_ATR_ATR_ST	P42771	CDKN2A	Q13535	ATR	S7	S12L	12	Missense	distal	5	no	13.128	13.135	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	10.658	Up-regulation
Atypical_PIKK_ATR_ATR_ST	P42771	CDKN2A	Q13535	ATR	S7	S8I	8	Missense	proximal	1	no	13.128	11.615	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	10.658	Down-regulation
Atypical_PIKK_ATR_ATR_ST	P42771	CDKN2A	Q13535	ATR	S7	S8R	8	Missense	proximal	1	no	13.128	12.109	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	10.658	Down-regulation
Atypical_PIKK_ATR_ATR_ST	P42771	CDKN2A	Q13535	ATR	S7	D14G	14	Missense	distal	7	no	13.128	12.937	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	10.658	Down-regulation
Atypical_PIKK_ATR_ATR_ST	P42771	CDKN2A	Q13535	ATR	S7	A13T	13	Missense	distal	6	no	13.128	13.407	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	10.658	Up-regulation
Atypical_PIKK_ATR_ATR_ST	P42771	CDKN2A	Q13535	ATR	S8	S12L	12	Missense	distal	4	no	14.293	14.531	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	10.658	Up-regulation
Atypical_PIKK_ATR_ATR_ST	P42771	CDKN2A	Q13535	ATR	S8	S8I	8	Missense	central	0	yes	14.293	0.000	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	10.658	Loss
Atypical_PIKK_ATR_ATR_ST	P42771	CDKN2A	Q13535	ATR	S8	S8R	8	Missense	central	0	yes	14.293	0.000	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	10.658	Loss
Atypical_PIKK_ATR_ATR_ST	P42771	CDKN2A	Q13535	ATR	S8	D14G	14	Missense	distal	6	no	14.293	14.241	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	10.658	Down-regulation
Atypical_PIKK_ATR_ATR_ST	P42771	CDKN2A	Q13535	ATR	S8	A13T	13	Missense	distal	5	no	14.293	14.291	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	10.658	Down-regulation
Atypical_PIKK_ATR_ATR_ST	P23508	MCC	Q13535	ATR	T803	R800K	800	Missense	distal	-3	no	15.892	15.280	EPSD	TCGA	10.658	Down-regulation
Atypical_PIKK_ATR_ATR_ST	P23508	MCC	Q13535	ATR	T803	L808F	808	Missense	distal	5	no	15.892	15.897	EPSD	TCGA;COSMIC	10.658	Up-regulation
Atypical_PIKK_ATR_ATR_ST	P23508	MCC	Q13535	ATR	T803	L808I	808	Missense	distal	5	no	15.892	15.897	EPSD	TCGA;COSMIC	10.658	Up-regulation
Atypical_PIKK_ATR_ATR_ST	O14757	CHEK1	Q13535	ATR	S296	Q295E	295	Missense	proximal	-1	no	15.413	15.498	PhosphoSitePlus;EPSD	TCGA;ICGC;COSMIC	10.658	Up-regulation
Atypical_PIKK_ATR_ATR_ST	O14757	CHEK1	Q13535	ATR	S296	G289V	289	Missense	distal	-7	no	15.413	15.404	PhosphoSitePlus;EPSD	TCGA;ICGC;COSMIC	10.658	Down-regulation
Atypical_PIKK_ATR_ATR_ST	O14757	CHEK1	Q13535	ATR	S296	S296F	296	Missense	central	0	yes	15.413	0.000	PhosphoSitePlus;EPSD	TCGA;ICGC;COSMIC	10.658	Loss
Atypical_PIKK_ATR_ATR_ST	O14757	CHEK1	Q13535	ATR	S296	N297T	297	Missense	proximal	1	no	15.413	10.170	PhosphoSitePlus;EPSD	TCGA;ICGC	10.658	Loss
Atypical_PIKK_ATR_ATR_ST	O14757	CHEK1	Q13535	ATR	S317	R322H	322	Missense	distal	5	no	17.676	17.670	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	10.658	Down-regulation
Atypical_PIKK_ATR_ATR_ST	O14757	CHEK1	Q13535	ATR	S317	G324C	324	Missense	distal	7	no	17.676	18.072	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	10.658	Up-regulation
Atypical_PIKK_ATR_ATR_ST	O14757	CHEK1	Q13535	ATR	S345	V339I	339	Missense	distal	-6	no	17.127	17.134	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	10.658	Up-regulation
Atypical_PIKK_ATR_ATR_ST	O14757	CHEK1	Q13535	ATR	S468	D464Y	464	Missense	distal	-4	no	10.983	7.755	EPSD	TCGA;ICGC;COSMIC	10.658	Loss
Atypical_PIKK_ATR_ATR_ST	Q12888	TP53BP1	Q13535	ATR	S452	S457C	457	Missense	distal	5	no	11.136	11.162	EPSD;PhosphoSitePlus	TCGA;COSMIC	10.658	Up-regulation
Atypical_PIKK_ATR_ATR_ST	Q12888	TP53BP1	Q13535	ATR	T543	E546K	546	Missense	distal	3	no	14.275	14.432	EPSD	TCGA	10.658	Up-regulation
Atypical_PIKK_ATR_ATR_ST	Q12888	TP53BP1	Q13535	ATR	S580	Q578H	578	Missense	proximal	-2	no	17.460	17.093	EPSD	TCGA;COSMIC	10.658	Down-regulation
Atypical_PIKK_ATR_ATR_ST	Q12888	TP53BP1	Q13535	ATR	S1304	S1311F	1311	Missense	distal	7	no	12.642	12.704	EPSD	TCGA;COSMIC	10.658	Up-regulation
Atypical_PIKK_ATR_ATR_ST	Q12888	TP53BP1	Q13535	ATR	S1678	R1682W	1682	Missense	distal	4	no	10.995	11.326	EPSD	TCGA;COSMIC	10.658	Up-regulation
Atypical_PIKK_ATR_ATR_ST	Q12888	TP53BP1	Q13535	ATR	S1678	R1682Q	1682	Missense	distal	4	no	10.995	10.829	EPSD	TCGA;COSMIC	10.658	Down-regulation
Atypical_PIKK_ATR_ATR_ST	Q96RL1	UIMC1	Q13535	ATR	T136	G137E	137	Missense	proximal	1	no	7.668	10.691	EPSD	TCGA;ICGC;COSMIC	10.658	Gain
Atypical_PIKK_ATR_ATR_ST	Q96RL1	UIMC1	Q13535	ATR	S140	Q144E	144	Missense	distal	4	no	13.466	13.338	EPSD	TCGA;ICGC;COSMIC	10.658	Down-regulation
Atypical_PIKK_ATR_ATR_ST	Q96RL1	UIMC1	Q13535	ATR	S140	S140F	140	Missense	central	0	yes	13.466	0.000	EPSD	TCGA;ICGC;COSMIC	10.658	Loss
Atypical_PIKK_ATR_ATR_ST	Q96RL1	UIMC1	Q13535	ATR	S140	G137E	137	Missense	distal	-3	no	13.466	13.625	EPSD	TCGA;ICGC;COSMIC	10.658	Up-regulation
Atypical_PIKK_ATR_ATR_ST	Q96RL1	UIMC1	Q13535	ATR	S171	I170M	170	Missense	proximal	-1	no	12.550	12.448	EPSD	TCGA;ICGC;COSMIC	10.658	Down-regulation
Atypical_PIKK_ATR_ATR_ST	Q96RL1	UIMC1	Q13535	ATR	S171	N174I	174	Missense	distal	3	no	12.550	12.814	EPSD	TCGA;ICGC;COSMIC	10.658	Up-regulation
Atypical_PIKK_ATR_ATR_ST	Q96RL1	UIMC1	Q13535	ATR	S379	K372E	372	Missense	distal	-7	no	10.760	10.777	EPSD	TCGA;ICGC;COSMIC	10.658	Up-regulation
Atypical_PIKK_ATR_ATR_ST	Q96RL1	UIMC1	Q13535	ATR	S379	S383R	383	Missense	distal	4	no	10.760	10.812	EPSD	TCGA;ICGC;COSMIC	10.658	Up-regulation
Atypical_PIKK_ATR_ATR_ST	Q96RL1	UIMC1	Q13535	ATR	S402	E408Q	408	Missense	distal	6	no	13.743	13.529	EPSD	TCGA;ICGC;COSMIC	10.658	Down-regulation
Atypical_PIKK_ATR_ATR_ST	Q96RL1	UIMC1	Q13535	ATR	S402	S402F	402	Missense	central	0	yes	13.743	0.000	EPSD	TCGA;ICGC;COSMIC	10.658	Loss
Atypical_PIKK_ATR_ATR_ST	Q96RL1	UIMC1	Q13535	ATR	T448	S452C	452	Missense	distal	4	no	12.626	13.315	EPSD	TCGA;ICGC;COSMIC	10.658	Up-regulation
Atypical_PIKK_ATR_ATR_ST	Q96RL1	UIMC1	Q13535	ATR	S643	I641M	641	Missense	proximal	-2	no	10.768	10.640	EPSD	TCGA;COSMIC	10.658	Loss
Atypical_PIKK_ATR_ATR_ST	Q96RL1	UIMC1	Q13535	ATR	S643	D638N	638	Missense	distal	-5	no	10.768	10.742	EPSD	TCGA;COSMIC	10.658	Down-regulation
Atypical_PIKK_ATR_ATR_ST	Q96RL1	UIMC1	Q13535	ATR	S643	S637L	637	Missense	distal	-6	no	10.768	10.878	EPSD	TCGA;COSMIC	10.658	Up-regulation
Atypical_PIKK_ATR_ATR_ST	Q96RL1	UIMC1	Q13535	ATR	S643	A648S	648	Missense	distal	5	no	10.768	10.757	EPSD	TCGA;COSMIC	10.658	Down-regulation
Atypical_PIKK_ATR_ATR_ST	Q96RL1	UIMC1	Q13535	ATR	S644	I641M	641	Missense	distal	-3	no	10.887	10.879	EPSD	TCGA;COSMIC	10.658	Down-regulation
Atypical_PIKK_ATR_ATR_ST	Q96RL1	UIMC1	Q13535	ATR	S644	D638N	638	Missense	distal	-6	no	10.887	10.890	EPSD	TCGA;COSMIC	10.658	Up-regulation
Atypical_PIKK_ATR_ATR_ST	Q96RL1	UIMC1	Q13535	ATR	S644	S637L	637	Missense	distal	-7	no	10.887	10.722	EPSD	TCGA;COSMIC	10.658	Down-regulation
Atypical_PIKK_ATR_ATR_ST	Q96RL1	UIMC1	Q13535	ATR	S644	A648S	648	Missense	distal	4	no	10.887	10.585	EPSD	TCGA;COSMIC	10.658	Loss
Atypical_PIKK_ATR_ATR_ST	Q96RL1	UIMC1	Q13535	ATR	S662	G660D	660	Missense	proximal	-2	no	10.850	10.929	EPSD	TCGA;COSMIC	10.658	Up-regulation
Atypical_PIKK_ATR_ATR_ST	Q96RL1	UIMC1	Q13535	ATR	S662	S662N	662	Missense	central	0	yes	10.850	0.000	EPSD	TCGA;COSMIC	10.658	Loss
Atypical_PIKK_ATR_ATR_ST	Q96RL1	UIMC1	Q13535	ATR	S677	L674I	674	Missense	distal	-3	no	12.139	11.592	EPSD	TCGA	10.658	Down-regulation
Atypical_PIKK_ATR_ATR_ST	Q96RL1	UIMC1	Q13535	ATR	S677	R672H	672	Missense	distal	-5	no	12.139	12.077	EPSD	TCGA;COSMIC;GDSC;CCLE	10.658	Down-regulation
Atypical_PIKK_ATR_ATR_ST	Q96RL1	UIMC1	Q13535	ATR	S677	R671C	671	Missense	distal	-6	no	12.139	12.126	EPSD	TCGA;COSMIC	10.658	Down-regulation
Atypical_PIKK_ATR_ATR_ST	P39880	CUX1	Q13535	ATR	S432	P438L	438	Missense	distal	6	no	12.920	12.992	EPSD	TCGA;ICGC;COSMIC	10.658	Up-regulation
Atypical_PIKK_ATR_ATR_ST	P39880	CUX1	Q13535	ATR	T658	R659Q	659	Missense	proximal	1	no	4.335	11.330	EPSD	TCGA;ICGC;COSMIC	10.658	Gain
Atypical_PIKK_ATR_ATR_ST	P39880	CUX1	Q13535	ATR	S1321	S1323G	1323	Missense	proximal	2	no	11.118	12.057	EPSD	TCGA;COSMIC	10.658	Up-regulation
Atypical_PIKK_ATR_ATR_ST	Q01094	E2F1	Q13535	ATR	S313	I306V	306	Missense	distal	-7	no	14.237	14.299	EPSD	TCGA;ICGC;COSMIC	10.658	Up-regulation
Atypical_PIKK_ATR_ATR_ST	Q01094	E2F1	Q13535	ATR	S347	P346L	346	Missense	proximal	-1	no	12.827	12.848	EPSD	TCGA;ICGC;COSMIC	10.658	Up-regulation
Atypical_PIKK_ATR_ATR_ST	Q01094	E2F1	Q13535	ATR	S349	P346L	346	Missense	distal	-3	no	10.790	11.085	EPSD	TCGA;ICGC;COSMIC	10.658	Up-regulation
Atypical_PIKK_ATR_ATR_ST	Q01094	E2F1	Q13535	ATR	S352	P346L	346	Missense	distal	-6	no	10.785	10.849	EPSD	TCGA;ICGC;COSMIC	10.658	Up-regulation
Atypical_PIKK_ATR_ATR_ST	Q01094	E2F1	Q13535	ATR	S364	G363R	363	Missense	proximal	-1	no	10.805	10.839	EPSD	TCGA;ICGC;COSMIC	10.658	Up-regulation
Atypical_PIKK_ATR_ATR_ST	P04637	TP53	Q13535	ATR	S6	P4L	4	Missense	proximal	-2	no	10.901	11.552	EPSD	TCGA;ICGC;COSMIC	10.658	Up-regulation
Atypical_PIKK_ATR_ATR_ST	P04637	TP53	Q13535	ATR	S99	G105C	105	Missense	distal	6	no	13.266	13.325	EPSD	TCGA;ICGC;COSMIC;GDSC	10.658	Up-regulation
Atypical_PIKK_ATR_ATR_ST	P04637	TP53	Q13535	ATR	S99	S106R	106	Missense	distal	7	no	13.266	13.490	EPSD	TCGA;ICGC;COSMIC;GDSC;CCLE	10.658	Up-regulation
Atypical_PIKK_ATR_ATR_ST	P04637	TP53	Q13535	ATR	S99	G105R	105	Missense	distal	6	no	13.266	13.112	EPSD	TCGA;ICGC;COSMIC;CCLE	10.658	Down-regulation
Atypical_PIKK_ATR_ATR_ST	P04637	TP53	Q13535	ATR	S99	G105V	105	Missense	distal	6	no	13.266	13.395	EPSD	TCGA;ICGC;COSMIC	10.658	Up-regulation
Atypical_PIKK_ATR_ATR_ST	P04637	TP53	Q13535	ATR	S99	G105D	105	Missense	distal	6	no	13.266	13.319	EPSD	TCGA;ICGC;COSMIC	10.658	Up-regulation
Atypical_PIKK_ATR_ATR_ST	P04637	TP53	Q13535	ATR	S99	G105S	105	Missense	distal	6	no	13.266	13.508	EPSD	TCGA;ICGC;COSMIC	10.658	Up-regulation
Atypical_PIKK_ATR_ATR_ST	P04637	TP53	Q13535	ATR	S99	V97D	97	Missense	proximal	-2	no	13.266	13.402	EPSD	TCGA;ICGC;COSMIC	10.658	Up-regulation
Atypical_PIKK_ATR_ATR_ST	P04637	TP53	Q13535	ATR	S99	P92S	92	Missense	distal	-7	no	13.266	13.238	EPSD	TCGA;ICGC	10.658	Down-regulation
Atypical_PIKK_ATR_ATR_ST	P04637	TP53	Q13535	ATR	S106	G105C	105	Missense	proximal	-1	no	11.409	11.867	EPSD	TCGA;ICGC;COSMIC;GDSC	10.658	Up-regulation
Atypical_PIKK_ATR_ATR_ST	P04637	TP53	Q13535	ATR	S106	R110L	110	Missense	distal	4	no	11.409	11.594	EPSD	TCGA;ICGC;COSMIC;GDSC;CCLE	10.658	Up-regulation
Atypical_PIKK_ATR_ATR_ST	P04637	TP53	Q13535	ATR	S106	L111R	111	Missense	distal	5	no	11.409	11.413	EPSD	TCGA;ICGC;COSMIC	10.658	Up-regulation
Atypical_PIKK_ATR_ATR_ST	P04637	TP53	Q13535	ATR	S106	L111P	111	Missense	distal	5	no	11.409	11.414	EPSD	TCGA;ICGC;COSMIC	10.658	Up-regulation
Atypical_PIKK_ATR_ATR_ST	P04637	TP53	Q13535	ATR	S106	L111Q	111	Missense	distal	5	no	11.409	11.404	EPSD	TCGA;ICGC;COSMIC	10.658	Down-regulation
Atypical_PIKK_ATR_ATR_ST	P04637	TP53	Q13535	ATR	S106	Y107D	107	Missense	proximal	1	no	11.409	12.309	EPSD	TCGA;ICGC;COSMIC	10.658	Up-regulation
Atypical_PIKK_ATR_ATR_ST	P04637	TP53	Q13535	ATR	S106	F113C	113	Missense	distal	7	no	11.409	11.709	EPSD	TCGA;ICGC;COSMIC;GDSC;CCLE	10.658	Up-regulation
Atypical_PIKK_ATR_ATR_ST	P04637	TP53	Q13535	ATR	S106	F113V	113	Missense	distal	7	no	11.409	11.558	EPSD	TCGA;ICGC;COSMIC;GDSC;CCLE	10.658	Up-regulation
Atypical_PIKK_ATR_ATR_ST	P04637	TP53	Q13535	ATR	S106	R110C	110	Missense	distal	4	no	11.409	12.046	EPSD	TCGA;ICGC;COSMIC;GDSC;CCLE	10.658	Up-regulation
Atypical_PIKK_ATR_ATR_ST	P04637	TP53	Q13535	ATR	S106	S106R	106	Missense	central	0	yes	11.409	0.000	EPSD	TCGA;ICGC;COSMIC;GDSC;CCLE	10.658	Loss
Atypical_PIKK_ATR_ATR_ST	P04637	TP53	Q13535	ATR	S106	F109S	109	Missense	distal	3	no	11.409	12.440	EPSD	TCGA;ICGC;COSMIC	10.658	Up-regulation
Atypical_PIKK_ATR_ATR_ST	P04637	TP53	Q13535	ATR	S106	G105R	105	Missense	proximal	-1	no	11.409	11.443	EPSD	TCGA;ICGC;COSMIC;CCLE	10.658	Up-regulation
Atypical_PIKK_ATR_ATR_ST	P04637	TP53	Q13535	ATR	S106	G105V	105	Missense	proximal	-1	no	11.409	11.336	EPSD	TCGA;ICGC;COSMIC	10.658	Down-regulation
Atypical_PIKK_ATR_ATR_ST	P04637	TP53	Q13535	ATR	S106	F109V	109	Missense	distal	3	no	11.409	12.540	EPSD	TCGA;ICGC;COSMIC	10.658	Up-regulation
Atypical_PIKK_ATR_ATR_ST	P04637	TP53	Q13535	ATR	S106	R110P	110	Missense	distal	4	no	11.409	11.443	EPSD	TCGA;ICGC;COSMIC;GDSC;CCLE	10.658	Up-regulation
Atypical_PIKK_ATR_ATR_ST	P04637	TP53	Q13535	ATR	S106	G105D	105	Missense	proximal	-1	no	11.409	11.503	EPSD	TCGA;ICGC;COSMIC	10.658	Up-regulation
Atypical_PIKK_ATR_ATR_ST	P04637	TP53	Q13535	ATR	S106	F109C	109	Missense	distal	3	no	11.409	12.138	EPSD	TCGA;ICGC;COSMIC	10.658	Up-regulation
Atypical_PIKK_ATR_ATR_ST	P04637	TP53	Q13535	ATR	S106	G105S	105	Missense	proximal	-1	no	11.409	11.316	EPSD	TCGA;ICGC;COSMIC	10.658	Down-regulation
Atypical_PIKK_ATR_ATR_ST	P04637	TP53	Q13535	ATR	S106	G108S	108	Missense	proximal	2	no	11.409	10.470	EPSD	TCGA;ICGC;COSMIC	10.658	Loss
Atypical_PIKK_ATR_ATR_ST	P04637	TP53	Q13535	ATR	S106	F113L	113	Missense	distal	7	no	11.409	11.509	EPSD	TCGA;ICGC;COSMIC;GDSC;CCLE	10.658	Up-regulation
Atypical_PIKK_ATR_ATR_ST	P04637	TP53	Q13535	ATR	T211	R213Q	213	Missense	proximal	2	no	10.866	10.955	EPSD	TCGA;ICGC;COSMIC;GDSC;CCLE	10.658	Up-regulation
Atypical_PIKK_ATR_ATR_ST	P04637	TP53	Q13535	ATR	T211	E204Q	204	Missense	distal	-7	no	10.866	10.821	EPSD	TCGA;ICGC;COSMIC	10.658	Down-regulation
Atypical_PIKK_ATR_ATR_ST	P04637	TP53	Q13535	ATR	T211	D208N	208	Missense	distal	-3	no	10.866	11.157	EPSD	TCGA;ICGC;COSMIC	10.658	Up-regulation
Atypical_PIKK_ATR_ATR_ST	P04637	TP53	Q13535	ATR	T211	H214R	214	Missense	distal	3	no	10.866	10.458	EPSD	TCGA;ICGC;COSMIC;GDSC;CCLE	10.658	Loss
Atypical_PIKK_ATR_ATR_ST	P04637	TP53	Q13535	ATR	T211	V218E	218	Missense	distal	7	no	10.866	10.617	EPSD	TCGA;ICGC;COSMIC	10.658	Loss
Atypical_PIKK_ATR_ATR_ST	P04637	TP53	Q13535	ATR	T211	S215I	215	Missense	distal	4	no	10.866	11.548	EPSD	TCGA;ICGC;COSMIC;GDSC;CCLE	10.658	Up-regulation
Atypical_PIKK_ATR_ATR_ST	P04637	TP53	Q13535	ATR	T211	V216M	216	Missense	distal	5	no	10.866	10.873	EPSD	TCGA;ICGC;COSMIC;GDSC;CCLE	10.658	Up-regulation
Atypical_PIKK_ATR_ATR_ST	P04637	TP53	Q13535	ATR	T211	Y205C	205	Missense	distal	-6	no	10.866	10.762	EPSD	TCGA;ICGC;COSMIC;GDSC;CCLE	10.658	Down-regulation
Atypical_PIKK_ATR_ATR_ST	P04637	TP53	Q13535	ATR	T211	Y205N	205	Missense	distal	-6	no	10.866	10.759	EPSD	TCGA;ICGC;COSMIC	10.658	Down-regulation
Atypical_PIKK_ATR_ATR_ST	P04637	TP53	Q13535	ATR	T211	S215N	215	Missense	distal	4	no	10.866	11.503	EPSD	TCGA;ICGC;COSMIC;GDSC;CCLE	10.658	Up-regulation
Atypical_PIKK_ATR_ATR_ST	P04637	TP53	Q13535	ATR	T211	T211I	211	Missense	central	0	yes	10.866	0.000	EPSD	TCGA;ICGC;COSMIC;CCLE	10.658	Loss
Atypical_PIKK_ATR_ATR_ST	P04637	TP53	Q13535	ATR	T211	V216G	216	Missense	distal	5	no	10.866	10.869	EPSD	TCGA;ICGC;COSMIC	10.658	Up-regulation
Atypical_PIKK_ATR_ATR_ST	P04637	TP53	Q13535	ATR	T211	R213L	213	Missense	proximal	2	no	10.866	10.174	EPSD	TCGA;ICGC;COSMIC;GDSC;CCLE	10.658	Loss
Atypical_PIKK_ATR_ATR_ST	P04637	TP53	Q13535	ATR	T211	V216E	216	Missense	distal	5	no	10.866	10.858	EPSD	TCGA;ICGC;COSMIC	10.658	Down-regulation
Atypical_PIKK_ATR_ATR_ST	P04637	TP53	Q13535	ATR	T211	R209K	209	Missense	proximal	-2	no	10.866	10.852	EPSD	TCGA;COSMIC	10.658	Down-regulation
Atypical_PIKK_ATR_ATR_ST	P04637	TP53	Q13535	ATR	T211	V218G	218	Missense	distal	7	no	10.866	10.622	EPSD	TCGA;ICGC;COSMIC	10.658	Loss
Atypical_PIKK_ATR_ATR_ST	P04637	TP53	Q13535	ATR	T211	R213P	213	Missense	proximal	2	no	10.866	11.455	EPSD	TCGA;ICGC;COSMIC	10.658	Up-regulation
Atypical_PIKK_ATR_ATR_ST	P04637	TP53	Q13535	ATR	T211	H214L	214	Missense	distal	3	no	10.866	10.226	EPSD	TCGA;ICGC;COSMIC	10.658	Loss
Atypical_PIKK_ATR_ATR_ST	P04637	TP53	Q13535	ATR	T211	Y205H	205	Missense	distal	-6	no	10.866	10.781	EPSD	TCGA;ICGC;COSMIC;CCLE	10.658	Down-regulation
Atypical_PIKK_ATR_ATR_ST	P04637	TP53	Q13535	ATR	T211	V216L	216	Missense	distal	5	no	10.866	10.871	EPSD	TCGA;ICGC;COSMIC;GDSC;CCLE	10.658	Up-regulation
Atypical_PIKK_ATR_ATR_ST	P04637	TP53	Q13535	ATR	T211	D208G	208	Missense	distal	-3	no	10.866	10.114	EPSD	TCGA;ICGC;COSMIC	10.658	Loss
Atypical_PIKK_ATR_ATR_ST	P04637	TP53	Q13535	ATR	T211	Y205S	205	Missense	distal	-6	no	10.866	10.693	EPSD	TCGA;ICGC;COSMIC	10.658	Down-regulation
Atypical_PIKK_ATR_ATR_ST	P04637	TP53	Q13535	ATR	T211	S215G	215	Missense	distal	4	no	10.866	11.635	EPSD	TCGA;ICGC;COSMIC;GDSC;CCLE	10.658	Up-regulation
Atypical_PIKK_ATR_ATR_ST	P04637	TP53	Q13535	ATR	T211	R209S	209	Missense	proximal	-2	no	10.866	10.456	EPSD	TCGA;ICGC;COSMIC	10.658	Loss
Atypical_PIKK_ATR_ATR_ST	P04637	TP53	Q13535	ATR	T211	R213G	213	Missense	proximal	2	no	10.866	12.078	EPSD	TCGA;ICGC;COSMIC	10.658	Up-regulation
Atypical_PIKK_ATR_ATR_ST	P04637	TP53	Q13535	ATR	T211	Y205F	205	Missense	distal	-6	no	10.866	10.772	EPSD	TCGA;ICGC;COSMIC;GDSC;CCLE	10.658	Down-regulation
Atypical_PIKK_ATR_ATR_ST	P04637	TP53	Q13535	ATR	T211	Y205D	205	Missense	distal	-6	no	10.866	10.756	EPSD	TCGA;ICGC;COSMIC	10.658	Down-regulation
Atypical_PIKK_ATR_ATR_ST	P04637	TP53	Q13535	ATR	T211	S215R	215	Missense	distal	4	no	10.866	10.918	EPSD	TCGA;ICGC;COSMIC;GDSC;CCLE	10.658	Up-regulation
Atypical_PIKK_ATR_ATR_ST	P04637	TP53	Q13535	ATR	T211	R209I	209	Missense	proximal	-2	no	10.866	10.953	EPSD	TCGA;ICGC;COSMIC	10.658	Up-regulation
Atypical_PIKK_ATR_ATR_ST	P04637	TP53	Q13535	ATR	T211	T211A	211	Missense	central	0	yes	10.866	0.000	EPSD	TCGA;ICGC;COSMIC;CCLE	10.658	Loss
Atypical_PIKK_ATR_ATR_ST	P04637	TP53	Q13535	ATR	T211	E204D	204	Missense	distal	-7	no	10.866	10.820	EPSD	TCGA;ICGC;COSMIC	10.658	Down-regulation
Atypical_PIKK_ATR_ATR_ST	P04637	TP53	Q13535	ATR	S215	V216M	216	Missense	proximal	1	no	-4.433	11.176	EPSD	TCGA;ICGC;COSMIC;GDSC;CCLE	10.658	Gain
Atypical_PIKK_ATR_ATR_ST	P04637	TP53	Q13535	ATR	T284	E285Q	285	Missense	proximal	1	no	9.305	15.226	EPSD	TCGA;ICGC;COSMIC	10.658	Gain
Atypical_PIKK_ATR_ATR_ST	Q00987	MDM2	Q13535	ATR	S17	T16A	16	Missense	proximal	-1	no	14.492	14.723	EPSD	TCGA;COSMIC	10.658	Up-regulation
Atypical_PIKK_ATR_ATR_ST	Q96SD1	DCLRE1C	Q13535	ATR	T251	R249C	249	Missense	proximal	-2	no	13.155	13.385	EPSD	TCGA;COSMIC	10.658	Up-regulation
Atypical_PIKK_ATR_ATR_ST	Q96SD1	DCLRE1C	Q13535	ATR	T251	C256F	256	Missense	distal	5	no	13.155	13.141	EPSD	TCGA;COSMIC	10.658	Down-regulation
Atypical_PIKK_ATR_ATR_ST	Q96SD1	DCLRE1C	Q13535	ATR	T251	Q252H	252	Missense	proximal	1	no	13.155	-4.363	EPSD	TCGA;COSMIC	10.658	Loss
Atypical_PIKK_ATR_ATR_ST	Q96SD1	DCLRE1C	Q13535	ATR	T251	R249H	249	Missense	proximal	-2	no	13.155	12.709	EPSD	TCGA;COSMIC	10.658	Down-regulation
Atypical_PIKK_ATR_ATR_ST	Q96SD1	DCLRE1C	Q13535	ATR	T251	R257Q	257	Missense	distal	6	no	13.155	13.423	EPSD	TCGA;COSMIC	10.658	Up-regulation
Atypical_PIKK_ATR_ATR_ST	Q96SD1	DCLRE1C	Q13535	ATR	T500	N496S	496	Missense	distal	-4	no	12.716	12.493	EPSD	TCGA	10.658	Down-regulation
Atypical_PIKK_ATR_ATR_ST	Q96SD1	DCLRE1C	Q13535	ATR	T500	R495I	495	Missense	distal	-5	no	12.716	12.737	EPSD	TCGA	10.658	Up-regulation
Atypical_PIKK_ATR_ATR_ST	Q96SD1	DCLRE1C	Q13535	ATR	S510	T511P	511	Missense	proximal	1	no	6.796	11.448	EPSD	TCGA	10.658	Gain
Atypical_PIKK_ATR_ATR_ST	Q96SD1	DCLRE1C	Q13535	ATR	S516	T511K	511	Missense	distal	-5	no	15.874	15.859	PhosphoSitePlus;EPSD	TCGA	10.658	Down-regulation
Atypical_PIKK_ATR_ATR_ST	Q96SD1	DCLRE1C	Q13535	ATR	S516	T511P	511	Missense	distal	-5	no	15.874	15.891	PhosphoSitePlus;EPSD	TCGA	10.658	Up-regulation
Atypical_PIKK_ATR_ATR_ST	Q96SD1	DCLRE1C	Q13535	ATR	S516	S509F	509	Missense	distal	-7	no	15.874	15.766	PhosphoSitePlus;EPSD	TCGA;COSMIC	10.658	Down-regulation
Atypical_PIKK_ATR_ATR_ST	Q96SD1	DCLRE1C	Q13535	ATR	S516	L521F	521	Missense	distal	5	no	15.874	15.879	PhosphoSitePlus;EPSD	TCGA;COSMIC	10.658	Up-regulation
Atypical_PIKK_ATR_ATR_ST	Q96SD1	DCLRE1C	Q13535	ATR	S534	T530I	530	Missense	distal	-4	no	14.932	13.676	EPSD	TCGA;COSMIC	10.658	Down-regulation
Atypical_PIKK_ATR_ATR_ST	Q96SD1	DCLRE1C	Q13535	ATR	S534	S537F	537	Missense	distal	3	no	14.932	13.901	EPSD	TCGA;COSMIC	10.658	Down-regulation
Atypical_PIKK_ATR_ATR_ST	Q96SD1	DCLRE1C	Q13535	ATR	S538	S537F	537	Missense	proximal	-1	no	11.890	11.892	EPSD	TCGA;COSMIC	10.658	Up-regulation
Atypical_PIKK_ATR_ATR_ST	Q96SD1	DCLRE1C	Q13535	ATR	S548	S548N	548	Missense	central	0	yes	14.606	0.000	EPSD	TCGA;COSMIC	10.658	Loss
Atypical_PIKK_ATR_ATR_ST	Q96SD1	DCLRE1C	Q13535	ATR	S553	S548N	548	Missense	distal	-5	no	14.312	14.454	EPSD	TCGA;COSMIC	10.658	Up-regulation
Atypical_PIKK_ATR_ATR_ST	Q96SD1	DCLRE1C	Q13535	ATR	S553	S548T	548	Missense	distal	-5	no	14.312	14.324	EPSD	TCGA;COSMIC	10.658	Up-regulation
Atypical_PIKK_ATR_ATR_ST	Q96SD1	DCLRE1C	Q13535	ATR	S553	D556N	556	Missense	distal	3	no	14.312	14.481	EPSD	TCGA;COSMIC	10.658	Up-regulation
Atypical_PIKK_ATR_ATR_ST	Q96SD1	DCLRE1C	Q13535	ATR	S553	D556G	556	Missense	distal	3	no	14.312	14.243	EPSD	TCGA;COSMIC	10.658	Down-regulation
Atypical_PIKK_ATR_ATR_ST	Q96SD1	DCLRE1C	Q13535	ATR	S562	D556N	556	Missense	distal	-6	no	15.032	15.035	EPSD	TCGA;COSMIC	10.658	Up-regulation
Atypical_PIKK_ATR_ATR_ST	Q96SD1	DCLRE1C	Q13535	ATR	S562	D556G	556	Missense	distal	-6	no	15.032	14.999	EPSD	TCGA;COSMIC	10.658	Down-regulation
Atypical_PIKK_ATR_ATR_ST	Q96SD1	DCLRE1C	Q13535	ATR	S645	N638T	638	Missense	distal	-7	no	16.135	16.211	EPSD;PhosphoSitePlus	TCGA;COSMIC	10.658	Up-regulation
Atypical_PIKK_ATR_ATR_ST	Q8WVB6	CHTF18	Q13535	ATR	S126	S125C	125	Missense	proximal	-1	no	10.410	10.962	EPSD	TCGA;COSMIC	10.658	Gain
Atypical_PIKK_ATR_ATR_ST	Q8WVB6	CHTF18	Q13535	ATR	S135	L139I	139	Missense	distal	4	no	11.554	12.000	EPSD	TCGA;COSMIC	10.658	Up-regulation
Atypical_PIKK_ATR_ATR_ST	Q8WVB6	CHTF18	Q13535	ATR	S135	P133L	133	Missense	proximal	-2	no	11.554	12.205	EPSD	TCGA;COSMIC	10.658	Up-regulation
Atypical_PIKK_ATR_ATR_ST	Q8WVB6	CHTF18	Q13535	ATR	S405	A400T	400	Missense	distal	-5	no	11.745	11.661	EPSD	TCGA;COSMIC;CCLE	10.658	Down-regulation
Atypical_PIKK_ATR_ATR_ST	Q8WVB6	CHTF18	Q13535	ATR	S405	R412H	412	Missense	distal	7	no	11.745	11.774	EPSD	TCGA;COSMIC	10.658	Up-regulation
Atypical_PIKK_ATR_ATR_ST	Q8WVB6	CHTF18	Q13535	ATR	S791	L792M	792	Missense	proximal	1	no	9.325	10.673	EPSD	TCGA;COSMIC	10.658	Gain
Atypical_PIKK_ATR_ATR_ST	P23025	XPA	Q13535	ATR	S173	H172Y	172	Missense	proximal	-1	no	16.194	16.505	EPSD;PhosphoSitePlus	TCGA;ICGC	10.658	Up-regulation
Atypical_PIKK_ATR_ATR_ST	P23025	XPA	Q13535	ATR	S196	S190F	190	Missense	distal	-6	no	16.492	16.572	PhosphoSitePlus;EPSD	TCGA;ICGC;COSMIC	10.658	Up-regulation
Atypical_PIKK_ATR_ATR_ST	P08047	SP1	Q13535	ATR	S7	D5Y	5	Missense	proximal	-2	no	11.664	12.111	EPSD	TCGA;ICGC;COSMIC	10.658	Up-regulation
Atypical_PIKK_ATR_ATR_ST	P08047	SP1	Q13535	ATR	S7	A13T	13	Missense	distal	6	no	11.664	11.943	EPSD	TCGA;ICGC;COSMIC	10.658	Up-regulation
Atypical_PIKK_ATR_ATR_ST	P08047	SP1	Q13535	ATR	S56	L61V	61	Missense	distal	5	no	15.878	15.873	EPSD	TCGA;ICGC;COSMIC	10.658	Down-regulation
Atypical_PIKK_ATR_ATR_ST	P08047	SP1	Q13535	ATR	S56	S59F	59	Missense	distal	3	no	15.878	14.847	EPSD	TCGA;ICGC;COSMIC	10.658	Down-regulation
Atypical_PIKK_ATR_ATR_ST	P08047	SP1	Q13535	ATR	S56	T49A	49	Missense	distal	-7	no	15.878	15.901	EPSD	TCGA;ICGC	10.658	Up-regulation
Atypical_PIKK_ATR_ATR_ST	P08047	SP1	Q13535	ATR	S73	S69N	69	Missense	distal	-4	no	12.796	13.019	EPSD	TCGA;ICGC;COSMIC	10.658	Up-regulation
Atypical_PIKK_ATR_ATR_ST	P08047	SP1	Q13535	ATR	S73	C68R	68	Missense	distal	-5	no	12.796	12.789	EPSD	TCGA;ICGC;COSMIC	10.658	Down-regulation
Atypical_PIKK_ATR_ATR_ST	P08047	SP1	Q13535	ATR	S73	P74S	74	Missense	proximal	1	no	12.796	11.687	EPSD	TCGA;ICGC;COSMIC	10.658	Down-regulation
Atypical_PIKK_ATR_ATR_ST	P08047	SP1	Q13535	ATR	S73	S78N	78	Missense	distal	5	no	12.796	12.801	EPSD	TCGA;ICGC;COSMIC	10.658	Up-regulation
Atypical_PIKK_ATR_ATR_ST	P08047	SP1	Q13535	ATR	S81	P74S	74	Missense	distal	-7	no	12.168	12.140	EPSD	TCGA;ICGC;COSMIC	10.658	Down-regulation
Atypical_PIKK_ATR_ATR_ST	P08047	SP1	Q13535	ATR	S81	S78N	78	Missense	distal	-3	no	12.168	13.253	EPSD	TCGA;ICGC;COSMIC	10.658	Up-regulation
Atypical_PIKK_ATR_ATR_ST	P08047	SP1	Q13535	ATR	S85	G89E	89	Missense	distal	4	no	13.390	12.379	EPSD	TCGA;ICGC;COSMIC	10.658	Down-regulation
Atypical_PIKK_ATR_ATR_ST	P08047	SP1	Q13535	ATR	S85	S78N	78	Missense	distal	-7	no	13.390	13.256	EPSD	TCGA;ICGC;COSMIC	10.658	Down-regulation
Atypical_PIKK_ATR_ATR_ST	P08047	SP1	Q13535	ATR	S588	D590E	590	Missense	proximal	2	no	9.560	11.236	EPSD	TCGA;ICGC;COSMIC	10.658	Gain
Atypical_PIKK_ATR_ATR_ST	P08047	SP1	Q13535	ATR	S732	G731S	731	Missense	proximal	-1	no	11.680	11.586	EPSD	TCGA;ICGC;COSMIC	10.658	Down-regulation
Atypical_PIKK_ATR_ATR_ST	P08047	SP1	Q13535	ATR	S732	S728C	728	Missense	distal	-4	no	11.680	10.391	EPSD	TCGA;ICGC;COSMIC	10.658	Loss
Atypical_PIKK_ATR_ATR_ST	P08047	SP1	Q13535	ATR	S732	G736S	736	Missense	distal	4	no	11.680	10.911	EPSD	TCGA;ICGC;COSMIC	10.658	Down-regulation
Atypical_PIKK_ATR_ATR_ST	P08047	SP1	Q13535	ATR	T739	I744F	744	Missense	distal	5	no	10.850	10.849	EPSD	TCGA;ICGC;COSMIC	10.658	Down-regulation
Atypical_PIKK_ATR_ATR_ST	P08047	SP1	Q13535	ATR	T739	A742T	742	Missense	distal	3	no	10.850	11.161	EPSD	TCGA;ICGC	10.658	Up-regulation
Atypical_PIKK_ATR_ATR_ST	P08047	SP1	Q13535	ATR	T739	G736S	736	Missense	distal	-3	no	10.850	10.808	EPSD	TCGA;ICGC;COSMIC	10.658	Down-regulation
Atypical_PIKK_ATR_ATR_ST	P38398	BRCA1	Q13535	ATR	S114	N113K	113	Missense	proximal	-1	no	16.320	15.736	EPSD	TCGA;ICGC;COSMIC	10.658	Down-regulation
Atypical_PIKK_ATR_ATR_ST	P38398	BRCA1	Q13535	ATR	S229	E230Q	230	Missense	proximal	1	no	8.331	14.251	EPSD	TCGA;ICGC;COSMIC	10.658	Gain
Atypical_PIKK_ATR_ATR_ST	P38398	BRCA1	Q13535	ATR	T231	N235D	235	Missense	distal	4	no	11.059	10.369	EPSD	TCGA;ICGC	10.658	Loss
Atypical_PIKK_ATR_ATR_ST	P38398	BRCA1	Q13535	ATR	T231	E230Q	230	Missense	proximal	-1	no	11.059	10.974	EPSD	TCGA;ICGC;COSMIC	10.658	Down-regulation
Atypical_PIKK_ATR_ATR_ST	P38398	BRCA1	Q13535	ATR	T231	T236S	236	Missense	distal	5	no	11.059	11.050	EPSD	TCGA;ICGC;COSMIC	10.658	Down-regulation
Atypical_PIKK_ATR_ATR_ST	P38398	BRCA1	Q13535	ATR	T231	A224S	224	Missense	distal	-7	no	11.059	11.093	EPSD	TCGA;ICGC;COSMIC	10.658	Up-regulation
Atypical_PIKK_ATR_ATR_ST	P38398	BRCA1	Q13535	ATR	S316	R320T	320	Missense	distal	4	no	13.275	13.274	EPSD	TCGA;COSMIC	10.658	Down-regulation
Atypical_PIKK_ATR_ATR_ST	P38398	BRCA1	Q13535	ATR	S316	W321C	321	Missense	distal	5	no	13.275	13.290	EPSD	TCGA;COSMIC	10.658	Up-regulation
Atypical_PIKK_ATR_ATR_ST	P38398	BRCA1	Q13535	ATR	S316	A314T	314	Missense	proximal	-2	no	13.275	12.802	EPSD	TCGA	10.658	Down-regulation
Atypical_PIKK_ATR_ATR_ST	P38398	BRCA1	Q13535	ATR	S425	E418D	418	Missense	distal	-7	no	13.755	13.709	EPSD	TCGA;COSMIC	10.658	Down-regulation
Atypical_PIKK_ATR_ATR_ST	P38398	BRCA1	Q13535	ATR	T528	V525A	525	Missense	distal	-3	no	11.844	12.243	EPSD	TCGA;COSMIC	10.658	Up-regulation
Atypical_PIKK_ATR_ATR_ST	P38398	BRCA1	Q13535	ATR	T528	P529S	529	Missense	proximal	1	no	11.844	10.734	EPSD	TCGA;COSMIC	10.658	Down-regulation
Atypical_PIKK_ATR_ATR_ST	P38398	BRCA1	Q13535	ATR	T528	A524T	524	Missense	distal	-4	no	11.844	11.236	EPSD	TCGA;COSMIC	10.658	Down-regulation
Atypical_PIKK_ATR_ATR_ST	P38398	BRCA1	Q13535	ATR	S646	S646G	646	Missense	central	0	yes	10.895	0.000	EPSD	TCGA;COSMIC	10.658	Loss
Atypical_PIKK_ATR_ATR_ST	P38398	BRCA1	Q13535	ATR	S646	C644W	644	Missense	proximal	-2	no	10.895	10.771	EPSD	TCGA;COSMIC	10.658	Down-regulation
Atypical_PIKK_ATR_ATR_ST	P38398	BRCA1	Q13535	ATR	S956	Q957E	957	Missense	proximal	1	no	12.178	6.257	EPSD	TCGA;COSMIC	10.658	Loss
Atypical_PIKK_ATR_ATR_ST	P38398	BRCA1	Q13535	ATR	S956	E962A	962	Missense	distal	6	no	12.178	11.766	EPSD	TCGA;COSMIC	10.658	Down-regulation
Atypical_PIKK_ATR_ATR_ST	P38398	BRCA1	Q13535	ATR	S1101	G1100R	1100	Missense	proximal	-1	no	11.797	11.831	EPSD	TCGA;COSMIC	10.658	Up-regulation
Atypical_PIKK_ATR_ATR_ST	P38398	BRCA1	Q13535	ATR	S1101	S1101R	1101	Missense	central	0	yes	11.797	0.000	EPSD	TCGA	10.658	Loss
Atypical_PIKK_ATR_ATR_ST	P38398	BRCA1	Q13535	ATR	S1143	H1141R	1141	Missense	proximal	-2	no	16.363	16.809	EPSD;PhosphoSitePlus	TCGA	10.658	Up-regulation
Atypical_PIKK_ATR_ATR_ST	P38398	BRCA1	Q13535	ATR	S1239	T1242A	1242	Missense	distal	3	no	14.724	14.412	EPSD	TCGA;COSMIC	10.658	Down-regulation
Atypical_PIKK_ATR_ATR_ST	P38398	BRCA1	Q13535	ATR	S1266	L1261V	1261	Missense	distal	-5	no	13.724	13.640	EPSD	TCGA;COSMIC	10.658	Down-regulation
Atypical_PIKK_ATR_ATR_ST	P38398	BRCA1	Q13535	ATR	T1312	I1318T	1318	Missense	distal	6	no	12.498	12.724	EPSD	TCGA;COSMIC	10.658	Up-regulation
Atypical_PIKK_ATR_ATR_ST	P38398	BRCA1	Q13535	ATR	T1312	N1309I	1309	Missense	distal	-3	no	12.498	11.437	EPSD	TCGA;COSMIC	10.658	Down-regulation
Atypical_PIKK_ATR_ATR_ST	P38398	BRCA1	Q13535	ATR	T1312	N1309H	1309	Missense	distal	-3	no	12.498	11.582	EPSD	TCGA;COSMIC	10.658	Down-regulation
Atypical_PIKK_ATR_ATR_ST	P38398	BRCA1	Q13535	ATR	T1312	T1310I	1310	Missense	proximal	-2	no	12.498	12.693	EPSD	TCGA;COSMIC	10.658	Up-regulation
Atypical_PIKK_ATR_ATR_ST	P38398	BRCA1	Q13535	ATR	T1312	P1315L	1315	Missense	distal	3	no	12.498	11.895	EPSD	TCGA;COSMIC	10.658	Down-regulation
Atypical_PIKK_ATR_ATR_ST	P38398	BRCA1	Q13535	ATR	T1394	T1399S	1399	Missense	distal	5	no	13.794	13.785	EPSD	TCGA;COSMIC	10.658	Down-regulation
Atypical_PIKK_ATR_ATR_ST	P38398	BRCA1	Q13535	ATR	T1394	R1397M	1397	Missense	distal	3	no	13.794	13.538	EPSD	TCGA;COSMIC	10.658	Down-regulation
Atypical_PIKK_ATR_ATR_ST	P38398	BRCA1	Q13535	ATR	S1423	E1419K	1419	Missense	distal	-4	no	15.492	15.082	EPSD;PhosphoSitePlus	TCGA;COSMIC	10.658	Down-regulation
Atypical_PIKK_ATR_ATR_ST	P38398	BRCA1	Q13535	ATR	S1423	G1422V	1422	Missense	proximal	-1	no	15.492	15.419	EPSD;PhosphoSitePlus	TCGA;COSMIC	10.658	Down-regulation
Atypical_PIKK_ATR_ATR_ST	Q9Y248	GINS2	Q13535	ATR	S182	S182P	182	Missense	central	0	yes	11.861	0.000	PhosphoSitePlus	TCGA;ICGC;COSMIC	10.658	Loss
Atypical_PIKK_ATR_ATR_ST	O43543	XRCC2	Q13535	ATR	S247	S250G	250	Missense	distal	3	no	14.696	14.202	PhosphoSitePlus	TCGA;ICGC;COSMIC	10.658	Down-regulation
Atypical_PIKK_ATR_ATR_ST	O43543	XRCC2	Q13535	ATR	S262	S257L	257	Missense	distal	-5	no	11.284	11.466	EPSD	TCGA;ICGC;COSMIC	10.658	Up-regulation
Atypical_PIKK_ATR_ATR_ST	O43543	XRCC2	Q13535	ATR	S262	N263K	263	Missense	proximal	1	no	11.284	4.594	EPSD	TCGA;ICGC;COSMIC	10.658	Loss
Atypical_PIKK_ATR_ATR_ST	O43543	XRCC2	Q13535	ATR	S262	R258H	258	Missense	distal	-4	no	11.284	11.285	EPSD	TCGA;GDSC;CCLE	10.658	Up-regulation
Atypical_PIKK_ATR_ATR_ST	Q9UBU7	DBF4	Q13535	ATR	S28	N25S	25	Missense	distal	-3	no	10.705	9.620	EPSD	TCGA;ICGC;COSMIC	10.658	Loss
Atypical_PIKK_ATR_ATR_ST	Q9UBU7	DBF4	Q13535	ATR	T98	R101Q	101	Missense	distal	3	no	12.350	12.356	EPSD	TCGA;ICGC;COSMIC	10.658	Up-regulation
Atypical_PIKK_ATR_ATR_ST	Q9UBU7	DBF4	Q13535	ATR	S381	S381C	381	Missense	central	0	yes	12.738	0.000	EPSD	TCGA;ICGC;COSMIC	10.658	Loss
Atypical_PIKK_ATR_ATR_ST	Q9UBU7	DBF4	Q13535	ATR	S381	S381Y	381	Missense	central	0	yes	12.738	0.000	EPSD	TCGA;ICGC;COSMIC	10.658	Loss
Atypical_PIKK_ATR_ATR_ST	Q9UBU7	DBF4	Q13535	ATR	T449	L453V	453	Missense	distal	4	no	15.505	15.430	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	10.658	Down-regulation
Atypical_PIKK_ATR_ATR_ST	Q9UBU7	DBF4	Q13535	ATR	T449	L453Q	453	Missense	distal	4	no	15.505	15.154	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	10.658	Down-regulation
Atypical_PIKK_ATR_ATR_ST	Q9UBU7	DBF4	Q13535	ATR	T449	R445I	445	Missense	distal	-4	no	15.505	14.461	EPSD;PhosphoSitePlus	TCGA;ICGC	10.658	Down-regulation
Atypical_PIKK_ATR_ATR_ST	Q9UBU7	DBF4	Q13535	ATR	S539	L543V	543	Missense	distal	4	no	16.416	16.341	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	10.658	Down-regulation
Atypical_PIKK_ATR_ATR_ST	Q9UBU7	DBF4	Q13535	ATR	S539	S538G	538	Missense	proximal	-1	no	16.416	16.509	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	10.658	Up-regulation
Atypical_PIKK_ATR_ATR_ST	Q9UBU7	DBF4	Q13535	ATR	S539	G532D	532	Missense	distal	-7	no	16.416	16.447	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	10.658	Up-regulation
Atypical_PIKK_ATR_ATR_ST	Q9UBU7	DBF4	Q13535	ATR	S539	H542D	542	Missense	distal	3	no	16.416	16.019	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	10.658	Down-regulation
Atypical_PIKK_ATR_ATR_ST	Q9UBU7	DBF4	Q13535	ATR	T638	N645K	645	Missense	distal	7	no	10.923	10.652	EPSD	TCGA;ICGC;COSMIC	10.658	Loss
Atypical_PIKK_ATR_ATR_ST	Q9UBU7	DBF4	Q13535	ATR	T638	G633D	633	Missense	distal	-5	no	10.923	11.075	EPSD	TCGA;ICGC;COSMIC	10.658	Up-regulation
Atypical_PIKK_ATR_ATR_ST	Q9UBU7	DBF4	Q13535	ATR	T638	I643M	643	Missense	distal	5	no	10.923	10.919	EPSD	TCGA;ICGC	10.658	Down-regulation
Atypical_PIKK_ATR_ATR_ST	Q9Y285	FARSA	Q13535	ATR	S109	A107V	107	Missense	proximal	-2	no	12.493	11.974	EPSD	TCGA	10.658	Down-regulation
Atypical_PIKK_ATR_ATR_ST	Q9Y285	FARSA	Q13535	ATR	S157	E158Q	158	Missense	proximal	1	no	7.406	13.327	EPSD	TCGA;COSMIC	10.658	Gain
Atypical_PIKK_ATR_ATR_ST	Q9Y285	FARSA	Q13535	ATR	S193	E195K	195	Missense	proximal	2	no	11.853	10.904	EPSD	TCGA;ICGC;COSMIC	10.658	Down-regulation
Atypical_PIKK_ATR_ATR_ST	Q9Y285	FARSA	Q13535	ATR	S301	G304D	304	Missense	distal	3	no	16.862	16.931	PhosphoSitePlus	TCGA;COSMIC	10.658	Up-regulation
Atypical_PIKK_ATR_ATR_ST	Q9Y285	FARSA	Q13535	ATR	S301	R295W	295	Missense	distal	-6	no	16.862	16.874	PhosphoSitePlus	TCGA;GDSC;CCLE	10.658	Up-regulation
Atypical_PIKK_ATR_ATR_ST	Q9Y285	FARSA	Q13535	ATR	S301	H300R	300	Missense	proximal	-1	no	16.862	16.968	PhosphoSitePlus	TCGA;COSMIC	10.658	Up-regulation
Atypical_PIKK_ATR_ATR_ST	Q9Y285	FARSA	Q13535	ATR	S307	G304D	304	Missense	distal	-3	no	14.382	15.134	EPSD	TCGA;COSMIC	10.658	Up-regulation
Atypical_PIKK_ATR_ATR_ST	Q9Y285	FARSA	Q13535	ATR	S307	H300R	300	Missense	distal	-7	no	14.382	14.330	EPSD	TCGA;COSMIC	10.658	Down-regulation
Atypical_PIKK_ATR_ATR_ST	Q9Y285	FARSA	Q13535	ATR	T504	P501S	501	Missense	distal	-3	no	10.949	10.673	EPSD	TCGA;COSMIC	10.658	Down-regulation
Atypical_PIKK_ATR_ATR_ST	Q9Y285	FARSA	Q13535	ATR	T504	P503S	503	Missense	proximal	-1	no	10.949	10.734	EPSD	TCGA;COSMIC	10.658	Down-regulation
Atypical_PIKK_ATR_ATR_ST	Q8IYD8	FANCM	Q13535	ATR	S14	Q10E	10	Missense	distal	-4	no	9.533	10.663	EPSD	TCGA;ICGC;COSMIC	10.658	Gain
Atypical_PIKK_ATR_ATR_ST	Q8IYD8	FANCM	Q13535	ATR	S52	D54G	54	Missense	proximal	2	no	9.301	10.848	EPSD	TCGA;ICGC;COSMIC	10.658	Gain
Atypical_PIKK_ATR_ATR_ST	Q8IYD8	FANCM	Q13535	ATR	T247	D251Y	251	Missense	distal	4	no	11.031	11.537	EPSD	TCGA;ICGC;COSMIC	10.658	Up-regulation
Atypical_PIKK_ATR_ATR_ST	Q8IYD8	FANCM	Q13535	ATR	T247	A254S	254	Missense	distal	7	no	11.031	10.960	EPSD	TCGA	10.658	Down-regulation
Atypical_PIKK_ATR_ATR_ST	Q8IYD8	FANCM	Q13535	ATR	T247	S250I	250	Missense	distal	3	no	11.031	11.040	EPSD	TCGA;ICGC	10.658	Up-regulation
Atypical_PIKK_ATR_ATR_ST	Q8IYD8	FANCM	Q13535	ATR	T397	R398Q	398	Missense	proximal	1	no	3.746	10.741	EPSD	TCGA;COSMIC	10.658	Gain
Atypical_PIKK_ATR_ATR_ST	Q8IYD8	FANCM	Q13535	ATR	S832	S832C	832	Missense	central	0	yes	11.894	0.000	EPSD	TCGA;COSMIC	10.658	Loss
Atypical_PIKK_ATR_ATR_ST	Q8IYD8	FANCM	Q13535	ATR	S1437	L1435F	1435	Missense	proximal	-2	no	11.242	11.138	EPSD	TCGA;COSMIC	10.658	Down-regulation
Atypical_PIKK_ATR_ATR_ST	Q8IYD8	FANCM	Q13535	ATR	S1686	A1689V	1689	Missense	distal	3	no	10.296	11.057	EPSD	TCGA;COSMIC	10.658	Gain
Atypical_PIKK_ATR_ATR_ST	Q8IYD8	FANCM	Q13535	ATR	S1836	H1841Y	1841	Missense	distal	5	no	11.868	11.884	EPSD	TCGA;ICGC	10.658	Up-regulation
Atypical_PIKK_ATR_ATR_ST	Q8IYD8	FANCM	Q13535	ATR	S1836	I1834M	1834	Missense	proximal	-2	no	11.868	11.740	EPSD	TCGA;ICGC;COSMIC	10.658	Down-regulation
Atypical_PIKK_ATR_ATR_ST	Q8IYD8	FANCM	Q13535	ATR	S2004	M2000L	2000	Missense	distal	-4	no	10.663	10.008	EPSD	TCGA	10.658	Loss
Atypical_PIKK_ATR_ATR_ST	Q8IYD8	FANCM	Q13535	ATR	S2004	M2000I	2000	Missense	distal	-4	no	10.663	9.540	EPSD	TCGA;ICGC;COSMIC	10.658	Loss
Atypical_PIKK_ATR_ATR_ST	Q8IYD8	FANCM	Q13535	ATR	S2004	S2004L	2004	Missense	central	0	yes	10.663	0.000	EPSD	TCGA;COSMIC	10.658	Loss
Atypical_PIKK_ATR_ATR_ST	P27707	DCK	Q13535	ATR	S15	F12V	12	Missense	distal	-3	no	11.612	11.193	EPSD	TCGA	10.658	Down-regulation
Atypical_PIKK_ATR_ATR_ST	P27707	DCK	Q13535	ATR	S15	S8N	8	Missense	distal	-7	no	11.612	11.478	EPSD	TCGA;ICGC;COSMIC	10.658	Down-regulation
Atypical_PIKK_ATR_ATR_ST	P27707	DCK	Q13535	ATR	T64	E69K	69	Missense	distal	5	no	13.776	13.785	EPSD	TCGA;ICGC;COSMIC	10.658	Up-regulation
Atypical_PIKK_ATR_ATR_ST	P27707	DCK	Q13535	ATR	T64	D66Y	66	Missense	proximal	2	no	13.776	12.104	EPSD	TCGA;ICGC	10.658	Down-regulation
Atypical_PIKK_ATR_ATR_ST	P27707	DCK	Q13535	ATR	S74	E69K	69	Missense	distal	-5	no	15.619	15.700	PhosphoSitePlus	TCGA;ICGC;COSMIC	10.658	Up-regulation
Atypical_PIKK_ATR_ATR_ST	Q9BXW9	FANCD2	Q13535	ATR	S15	D19Y	19	Missense	distal	4	no	13.481	13.987	EPSD	TCGA;ICGC;COSMIC	10.658	Up-regulation
Atypical_PIKK_ATR_ATR_ST	Q9BXW9	FANCD2	Q13535	ATR	S126	R119C	119	Missense	distal	-7	no	10.992	10.814	EPSD	TCGA;ICGC;COSMIC	10.658	Down-regulation
Atypical_PIKK_ATR_ATR_ST	Q9BXW9	FANCD2	Q13535	ATR	S167	F161V	161	Missense	distal	-6	no	11.652	11.650	EPSD	TCGA;ICGC;COSMIC	10.658	Down-regulation
Atypical_PIKK_ATR_ATR_ST	Q9BXW9	FANCD2	Q13535	ATR	S167	R174Q	174	Missense	distal	7	no	11.652	11.451	EPSD	TCGA;ICGC;COSMIC	10.658	Down-regulation
Atypical_PIKK_ATR_ATR_ST	Q9BXW9	FANCD2	Q13535	ATR	S178	R174Q	174	Missense	distal	-4	no	11.877	12.059	EPSD	TCGA;ICGC;COSMIC	10.658	Up-regulation
Atypical_PIKK_ATR_ATR_ST	Q9BXW9	FANCD2	Q13535	ATR	S178	R185T	185	Missense	distal	7	no	11.877	11.825	EPSD	TCGA;ICGC;COSMIC	10.658	Down-regulation
Atypical_PIKK_ATR_ATR_ST	Q9BXW9	FANCD2	Q13535	ATR	S319	L312W	312	Missense	distal	-7	no	15.682	15.742	EPSD	TCGA;ICGC;COSMIC	10.658	Up-regulation
Atypical_PIKK_ATR_ATR_ST	Q9BXW9	FANCD2	Q13535	ATR	T596	A600G	600	Missense	distal	4	no	14.160	14.627	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	10.658	Up-regulation
Atypical_PIKK_ATR_ATR_ST	Q9BXW9	FANCD2	Q13535	ATR	T608	Q609H	609	Missense	proximal	1	no	17.179	-0.339	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	10.658	Loss
Atypical_PIKK_ATR_ATR_ST	Q9BXW9	FANCD2	Q13535	ATR	T691	G685A	685	Missense	distal	-6	no	15.569	15.647	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	10.658	Up-regulation
Atypical_PIKK_ATR_ATR_ST	Q9BXW9	FANCD2	Q13535	ATR	T691	E687K	687	Missense	distal	-4	no	15.569	15.158	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	10.658	Down-regulation
Atypical_PIKK_ATR_ATR_ST	Q9BXW9	FANCD2	Q13535	ATR	S717	V715A	715	Missense	proximal	-2	no	17.875	18.395	PhosphoSitePlus;EPSD	TCGA;ICGC;COSMIC	10.658	Up-regulation
Atypical_PIKK_ATR_ATR_ST	Q9BXW9	FANCD2	Q13535	ATR	S886	S886L	886	Missense	central	0	yes	10.866	0.000	EPSD	TCGA;ICGC;COSMIC	10.658	Loss
Atypical_PIKK_ATR_ATR_ST	Q9BXW9	FANCD2	Q13535	ATR	S886	E888D	888	Missense	proximal	2	no	10.866	9.190	EPSD	TCGA;ICGC;COSMIC	10.658	Loss
Atypical_PIKK_ATR_ATR_ST	Q9BXW9	FANCD2	Q13535	ATR	S1257	E1262D	1262	Missense	distal	5	no	14.367	14.381	EPSD	TCGA;ICGC;COSMIC	10.658	Up-regulation
Atypical_PIKK_ATR_ATR_ST	Q9BXW9	FANCD2	Q13535	ATR	S1257	S1257W	1257	Missense	central	0	yes	14.367	0.000	EPSD	TCGA;ICGC;COSMIC	10.658	Loss
Atypical_PIKK_ATR_ATR_ST	Q9BXW9	FANCD2	Q13535	ATR	S1257	S1257L	1257	Missense	central	0	yes	14.367	0.000	EPSD	TCGA;ICGC;COSMIC	10.658	Loss
Atypical_PIKK_ATR_ATR_ST	Q9BXW9	FANCD2	Q13535	ATR	S1401	S1404F	1404	Missense	distal	3	no	14.045	13.014	EPSD	TCGA;ICGC;COSMIC	10.658	Down-regulation
Atypical_PIKK_ATR_ATR_ST	Q9BXW9	FANCD2	Q13535	ATR	S1404	S1404F	1404	Missense	central	0	yes	15.589	0.000	EPSD	TCGA;ICGC;COSMIC	10.658	Loss
Atypical_PIKK_ATR_ATR_ST	Q9BXW9	FANCD2	Q13535	ATR	S1443	G1437C	1437	Missense	distal	-6	no	10.977	11.016	EPSD	TCGA;ICGC;COSMIC	10.658	Up-regulation
Atypical_PIKK_ATR_ATR_ST	P06748	NPM1	Q13535	ATR	S10	L12M	12	Missense	proximal	2	no	10.443	11.814	EPSD	TCGA;ICGC;COSMIC	10.658	Gain
Atypical_PIKK_ATR_ATR_ST	P06748	NPM1	Q13535	ATR	S43	V47F	47	Missense	distal	4	no	12.372	12.228	EPSD	TCGA;ICGC;COSMIC	10.658	Down-regulation
Atypical_PIKK_ATR_ATR_ST	P06748	NPM1	Q13535	ATR	S43	E37G	37	Missense	distal	-6	no	12.372	12.346	EPSD	TCGA;ICGC;COSMIC	10.658	Down-regulation
Atypical_PIKK_ATR_ATR_ST	P06748	NPM1	Q13535	ATR	S43	S43Y	43	Missense	central	0	yes	12.372	0.000	EPSD	TCGA;ICGC;COSMIC	10.658	Loss
Atypical_PIKK_ATR_ATR_ST	P06748	NPM1	Q13535	ATR	T199	I196V	196	Missense	distal	-3	no	10.691	11.107	EPSD	TCGA;ICGC;COSMIC	10.658	Up-regulation
Atypical_PIKK_ATR_ATR_ST	P06748	NPM1	Q13535	ATR	S242	K239N	239	Missense	distal	-3	no	9.899	11.059	EPSD	TCGA;ICGC;COSMIC	10.658	Gain
Atypical_PIKK_ATR_ATR_ST	P15927	RPA2	Q13535	ATR	T21	T21P	21	Missense	central	0	yes	16.057	0.000	EPSD;PhosphoSitePlus	TCGA	10.658	Loss
Atypical_PIKK_ATR_ATR_ST	P15927	RPA2	Q13535	ATR	T21	S23F	23	Missense	proximal	2	no	16.057	13.369	EPSD;PhosphoSitePlus	TCGA;COSMIC	10.658	Down-regulation
Atypical_PIKK_ATR_ATR_ST	P15927	RPA2	Q13535	ATR	T21	G19D	19	Missense	proximal	-2	no	16.057	16.136	EPSD;PhosphoSitePlus	TCGA;COSMIC	10.658	Up-regulation
Atypical_PIKK_ATR_ATR_ST	P15927	RPA2	Q13535	ATR	T21	G26S	26	Missense	distal	5	no	16.057	16.051	EPSD;PhosphoSitePlus	TCGA;COSMIC	10.658	Down-regulation
Atypical_PIKK_ATR_ATR_ST	P15927	RPA2	Q13535	ATR	S23	T21P	21	Missense	proximal	-2	no	11.157	10.907	EPSD	TCGA	10.658	Down-regulation
Atypical_PIKK_ATR_ATR_ST	P15927	RPA2	Q13535	ATR	S23	S23F	23	Missense	central	0	yes	11.157	0.000	EPSD	TCGA;COSMIC	10.658	Loss
Atypical_PIKK_ATR_ATR_ST	P15927	RPA2	Q13535	ATR	S23	S29L	29	Missense	distal	6	no	11.157	10.933	EPSD	TCGA;COSMIC	10.658	Down-regulation
Atypical_PIKK_ATR_ATR_ST	P15927	RPA2	Q13535	ATR	S23	G19D	19	Missense	distal	-4	no	11.157	12.507	EPSD	TCGA;COSMIC	10.658	Up-regulation
Atypical_PIKK_ATR_ATR_ST	P15927	RPA2	Q13535	ATR	S23	G26S	26	Missense	distal	3	no	11.157	11.651	EPSD	TCGA;COSMIC	10.658	Up-regulation
Atypical_PIKK_ATR_ATR_ST	P15927	RPA2	Q13535	ATR	S33	E36A	36	Missense	distal	3	no	17.862	17.515	PhosphoSitePlus;EPSD	TCGA;COSMIC	10.658	Down-regulation
Atypical_PIKK_ATR_ATR_ST	P15927	RPA2	Q13535	ATR	S33	S29L	29	Missense	distal	-4	no	17.862	16.987	PhosphoSitePlus;EPSD	TCGA;COSMIC	10.658	Down-regulation
Atypical_PIKK_ATR_ATR_ST	P15927	RPA2	Q13535	ATR	S33	G26S	26	Missense	distal	-7	no	17.862	17.909	PhosphoSitePlus;EPSD	TCGA;COSMIC	10.658	Up-regulation
Atypical_PIKK_ATR_ATR_ST	P15927	RPA2	Q13535	ATR	S33	S39A	39	Missense	distal	6	no	17.862	17.536	PhosphoSitePlus;EPSD	TCGA;COSMIC	10.658	Down-regulation
Atypical_PIKK_ATR_ATR_ST	P15927	RPA2	Q13535	ATR	S52	Q53H	53	Missense	proximal	1	no	14.938	-2.580	EPSD;PhosphoSitePlus	TCGA;COSMIC	10.658	Loss
Atypical_PIKK_ATR_ATR_ST	P15927	RPA2	Q13535	ATR	S52	A57V	57	Missense	distal	5	no	14.938	14.929	EPSD;PhosphoSitePlus	TCGA;COSMIC	10.658	Down-regulation
Atypical_PIKK_ATR_ATR_ST	P15927	RPA2	Q13535	ATR	S72	G67W	67	Missense	distal	-5	no	15.886	16.082	EPSD;PhosphoSitePlus	TCGA;COSMIC	10.658	Up-regulation
Atypical_PIKK_ATR_ATR_ST	P15927	RPA2	Q13535	ATR	T88	K85N	85	Missense	distal	-3	no	9.535	10.695	EPSD	TCGA;COSMIC	10.658	Gain
Atypical_PIKK_ATR_ATR_ST	P15927	RPA2	Q13535	ATR	S114	D109G	109	Missense	distal	-5	no	12.522	12.370	EPSD	TCGA;COSMIC	10.658	Down-regulation
Atypical_PIKK_ATR_ATR_ST	P15927	RPA2	Q13535	ATR	S114	T118A	118	Missense	distal	4	no	12.522	12.773	EPSD	TCGA	10.658	Up-regulation
Atypical_PIKK_ATR_ATR_ST	Q9NZC9	SMARCAL1	Q13535	ATR	S115	R114C	114	Missense	proximal	-1	no	11.322	11.747	EPSD	TCGA;ICGC;COSMIC	10.658	Up-regulation
Atypical_PIKK_ATR_ATR_ST	Q9NZC9	SMARCAL1	Q13535	ATR	S140	L139F	139	Missense	proximal	-1	no	10.983	10.749	EPSD	TCGA;ICGC;COSMIC	10.658	Down-regulation
Atypical_PIKK_ATR_ATR_ST	Q9NZC9	SMARCAL1	Q13535	ATR	S173	H179Y	179	Missense	distal	6	no	13.969	13.794	EPSD	TCGA;ICGC;COSMIC	10.658	Down-regulation
Atypical_PIKK_ATR_ATR_ST	Q9NZC9	SMARCAL1	Q13535	ATR	S173	S180F	180	Missense	distal	7	no	13.969	14.030	EPSD	TCGA;ICGC;COSMIC	10.658	Up-regulation
Atypical_PIKK_ATR_ATR_ST	Q9NZC9	SMARCAL1	Q13535	ATR	S180	H179Y	179	Missense	proximal	-1	no	10.862	11.173	EPSD	TCGA;ICGC;COSMIC	10.658	Up-regulation
Atypical_PIKK_ATR_ATR_ST	Q9NZC9	SMARCAL1	Q13535	ATR	S180	S181C	181	Missense	proximal	1	no	10.862	4.160	EPSD	TCGA;ICGC;COSMIC	10.658	Loss
Atypical_PIKK_ATR_ATR_ST	Q9NZC9	SMARCAL1	Q13535	ATR	S180	S180F	180	Missense	central	0	yes	10.862	0.000	EPSD	TCGA;ICGC;COSMIC	10.658	Loss
Atypical_PIKK_ATR_ATR_ST	Q9NZC9	SMARCAL1	Q13535	ATR	S627	K634N	634	Missense	distal	7	no	11.757	12.027	EPSD	TCGA;ICGC;COSMIC	10.658	Up-regulation
Atypical_PIKK_ATR_ATR_ST	Q9NZC9	SMARCAL1	Q13535	ATR	S652	R659H	659	Missense	distal	7	no	14.972	15.002	PhosphoSitePlus	TCGA	10.658	Up-regulation
Atypical_PIKK_ATR_ATR_ST	Q9NZC9	SMARCAL1	Q13535	ATR	S652	R659C	659	Missense	distal	7	no	14.972	15.111	PhosphoSitePlus	TCGA;ICGC;CCLE	10.658	Up-regulation
Atypical_PIKK_ATR_ATR_ST	Q9NZC9	SMARCAL1	Q13535	ATR	S652	R645C	645	Missense	distal	-7	no	14.972	14.795	PhosphoSitePlus	TCGA;ICGC;COSMIC	10.658	Down-regulation
Atypical_PIKK_ATR_ATR_ST	Q9NZC9	SMARCAL1	Q13535	ATR	S652	S652F	652	Missense	central	0	yes	14.972	0.000	PhosphoSitePlus	TCGA;ICGC;COSMIC	10.658	Loss
Atypical_PIKK_ATR_ATR_ST	Q9NZC9	SMARCAL1	Q13535	ATR	S652	S648F	648	Missense	distal	-4	no	14.972	14.689	PhosphoSitePlus	TCGA;ICGC;COSMIC	10.658	Down-regulation
Atypical_PIKK_ATR_ATR_ST	Q9NZC9	SMARCAL1	Q13535	ATR	S652	D649N	649	Missense	distal	-3	no	14.972	15.264	PhosphoSitePlus	TCGA;ICGC;COSMIC	10.658	Up-regulation
Atypical_PIKK_ATR_ATR_ST	Q9NZC9	SMARCAL1	Q13535	ATR	S895	E891D	891	Missense	distal	-4	no	11.599	11.417	EPSD	TCGA;ICGC;COSMIC	10.658	Down-regulation
Atypical_PIKK_ATR_ATR_ST	Q9NZC9	SMARCAL1	Q13535	ATR	S895	D896G	896	Missense	proximal	1	no	11.599	8.069	EPSD	TCGA;ICGC;COSMIC	10.658	Loss
Atypical_PIKK_ATR_ATR_ST	Q9NZC9	SMARCAL1	Q13535	ATR	S919	D924N	924	Missense	distal	5	no	11.858	11.854	EPSD	TCGA;ICGC;COSMIC	10.658	Down-regulation
Atypical_PIKK_ATR_ATR_ST	Q14683	SMC1A	Q13535	ATR	S85	E90K	90	Missense	distal	5	no	11.105	11.114	EPSD	TCGA;ICGC;COSMIC	10.658	Up-regulation
Atypical_PIKK_ATR_ATR_ST	Q14683	SMC1A	Q13535	ATR	T182	R188C	188	Missense	distal	6	no	10.589	10.802	EPSD	TCGA;ICGC;COSMIC	10.658	Gain
Atypical_PIKK_ATR_ATR_ST	Q14683	SMC1A	Q13535	ATR	T182	R188H	188	Missense	distal	6	no	10.589	10.664	EPSD	TCGA;ICGC;COSMIC	10.658	Gain
Atypical_PIKK_ATR_ATR_ST	Q14683	SMC1A	Q13535	ATR	T182	D181N	181	Missense	proximal	-1	no	10.589	10.879	EPSD	TCGA;ICGC	10.658	Gain
Atypical_PIKK_ATR_ATR_ST	Q14683	SMC1A	Q13535	ATR	T182	F184L	184	Missense	proximal	2	no	10.589	12.311	EPSD	TCGA;ICGC;COSMIC	10.658	Gain
Atypical_PIKK_ATR_ATR_ST	Q14683	SMC1A	Q13535	ATR	T182	K189N	189	Missense	distal	7	no	10.589	10.859	EPSD	TCGA;ICGC;COSMIC	10.658	Gain
Atypical_PIKK_ATR_ATR_ST	Q14683	SMC1A	Q13535	ATR	S358	E357D	357	Missense	proximal	-1	no	15.528	15.573	EPSD	TCGA;ICGC;COSMIC	10.658	Up-regulation
Atypical_PIKK_ATR_ATR_ST	Q14683	SMC1A	Q13535	ATR	S358	E357K	357	Missense	proximal	-1	no	15.528	15.279	EPSD	TCGA;ICGC;COSMIC	10.658	Down-regulation
Atypical_PIKK_ATR_ATR_ST	Q14683	SMC1A	Q13535	ATR	S358	R353W	353	Missense	distal	-5	no	15.528	15.559	EPSD	TCGA;ICGC;COSMIC	10.658	Up-regulation
Atypical_PIKK_ATR_ATR_ST	Q14683	SMC1A	Q13535	ATR	S360	E357D	357	Missense	distal	-3	no	13.881	14.474	EPSD	TCGA;ICGC;COSMIC	10.658	Up-regulation
Atypical_PIKK_ATR_ATR_ST	Q14683	SMC1A	Q13535	ATR	S360	E357K	357	Missense	distal	-3	no	13.881	13.606	EPSD	TCGA;ICGC;COSMIC	10.658	Down-regulation
Atypical_PIKK_ATR_ATR_ST	Q14683	SMC1A	Q13535	ATR	S360	R353W	353	Missense	distal	-7	no	13.881	13.823	EPSD	TCGA;ICGC;COSMIC	10.658	Down-regulation
Atypical_PIKK_ATR_ATR_ST	Q14683	SMC1A	Q13535	ATR	S703	R699C	699	Missense	distal	-4	no	14.499	13.508	EPSD	TCGA;ICGC;COSMIC	10.658	Down-regulation
Atypical_PIKK_ATR_ATR_ST	Q14683	SMC1A	Q13535	ATR	S703	S703P	703	Missense	central	0	yes	14.499	0.000	EPSD	TCGA;ICGC	10.658	Loss
Atypical_PIKK_ATR_ATR_ST	Q14683	SMC1A	Q13535	ATR	S715	D718E	718	Missense	distal	3	no	12.596	12.706	EPSD	TCGA;ICGC;COSMIC	10.658	Up-regulation
Atypical_PIKK_ATR_ATR_ST	Q14683	SMC1A	Q13535	ATR	S715	R711W	711	Missense	distal	-4	no	12.596	13.054	EPSD	TCGA;ICGC;COSMIC;GDSC;CCLE	10.658	Up-regulation
Atypical_PIKK_ATR_ATR_ST	Q14683	SMC1A	Q13535	ATR	S715	R711Q	711	Missense	distal	-4	no	12.596	12.778	EPSD	TCGA;ICGC;COSMIC;GDSC;CCLE	10.658	Up-regulation
Atypical_PIKK_ATR_ATR_ST	Q14683	SMC1A	Q13535	ATR	S957	E960G	960	Missense	distal	3	no	17.580	17.401	PhosphoSitePlus;EPSD	TCGA;ICGC;COSMIC	10.658	Down-regulation
Atypical_PIKK_ATR_ATR_ST	Q14683	SMC1A	Q13535	ATR	S966	Y973C	973	Missense	distal	7	no	16.361	16.538	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	10.658	Up-regulation
Atypical_PIKK_ATR_ATR_ST	Q14683	SMC1A	Q13535	ATR	S966	E960G	960	Missense	distal	-6	no	16.361	16.335	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	10.658	Down-regulation
Atypical_PIKK_ATR_ATR_ST	Q14683	SMC1A	Q13535	ATR	S1188	V1186A	1186	Missense	proximal	-2	no	11.903	12.423	EPSD	TCGA;ICGC;COSMIC	10.658	Up-regulation
Atypical_PIKK_ATR_ATR_ST	P54132	BLM	Q13535	ATR	T20	R15C	15	Missense	distal	-5	no	10.871	10.878	EPSD	TCGA;ICGC;COSMIC	10.658	Up-regulation
Atypical_PIKK_ATR_ATR_ST	P54132	BLM	Q13535	ATR	T50	S48F	48	Missense	proximal	-2	no	10.239	10.837	EPSD	TCGA;ICGC;COSMIC	10.658	Gain
Atypical_PIKK_ATR_ATR_ST	P54132	BLM	Q13535	ATR	T99	Q100H	100	Missense	proximal	1	no	15.027	-2.491	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	10.658	Loss
Atypical_PIKK_ATR_ATR_ST	P54132	BLM	Q13535	ATR	T99	A93D	93	Missense	distal	-6	no	15.027	14.983	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	10.658	Down-regulation
Atypical_PIKK_ATR_ATR_ST	P54132	BLM	Q13535	ATR	T99	Q97H	97	Missense	proximal	-2	no	15.027	14.660	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	10.658	Down-regulation
Atypical_PIKK_ATR_ATR_ST	P54132	BLM	Q13535	ATR	T114	D110N	110	Missense	distal	-4	no	12.221	11.612	EPSD	TCGA;ICGC;COSMIC	10.658	Down-regulation
Atypical_PIKK_ATR_ATR_ST	P54132	BLM	Q13535	ATR	T122	T125P	125	Missense	distal	3	no	14.365	14.650	PhosphoSitePlus;EPSD	TCGA;ICGC;COSMIC	10.658	Up-regulation
Atypical_PIKK_ATR_ATR_ST	P54132	BLM	Q13535	ATR	S314	S310C	310	Missense	distal	-4	no	11.794	10.505	EPSD	TCGA;ICGC	10.658	Loss
Atypical_PIKK_ATR_ATR_ST	P54132	BLM	Q13535	ATR	S449	G447R	447	Missense	proximal	-2	no	11.788	11.885	EPSD	TCGA;ICGC	10.658	Up-regulation
Atypical_PIKK_ATR_ATR_ST	P54132	BLM	Q13535	ATR	S449	S449Y	449	Missense	central	0	yes	11.788	0.000	EPSD	TCGA;ICGC	10.658	Loss
Atypical_PIKK_ATR_ATR_ST	P54132	BLM	Q13535	ATR	S460	S462Y	462	Missense	proximal	2	no	10.853	8.573	EPSD	TCGA;ICGC;COSMIC	10.658	Loss
Atypical_PIKK_ATR_ATR_ST	P54132	BLM	Q13535	ATR	S706	C704R	704	Missense	proximal	-2	no	13.852	13.623	EPSD	TCGA	10.658	Down-regulation
Atypical_PIKK_ATR_ATR_ST	P54132	BLM	Q13535	ATR	T907	R910T	910	Missense	distal	3	no	12.034	12.121	EPSD	TCGA;ICGC;COSMIC	10.658	Up-regulation
Atypical_PIKK_ATR_ATR_ST	P54132	BLM	Q13535	ATR	T907	D902H	902	Missense	distal	-5	no	12.034	11.986	EPSD	TCGA;ICGC;COSMIC	10.658	Down-regulation
Atypical_PIKK_ATR_ATR_ST	P54132	BLM	Q13535	ATR	T907	A914T	914	Missense	distal	7	no	12.034	12.135	EPSD	TCGA;ICGC	10.658	Up-regulation
Atypical_PIKK_ATR_ATR_ST	P54132	BLM	Q13535	ATR	T907	L913R	913	Missense	distal	6	no	12.034	11.862	EPSD	TCGA;ICGC;COSMIC	10.658	Down-regulation
Atypical_PIKK_ATR_ATR_ST	P54132	BLM	Q13535	ATR	S1254	D1256E	1256	Missense	proximal	2	no	9.271	10.947	EPSD	TCGA;ICGC;COSMIC	10.658	Gain
Atypical_PIKK_ATR_ATR_ST	P54132	BLM	Q13535	ATR	S1304	G1308R	1308	Missense	distal	4	no	13.149	12.432	EPSD	TCGA;ICGC;COSMIC	10.658	Down-regulation
Atypical_PIKK_ATR_ATR_ST	Q8IX01	SUGP2	Q13535	ATR	T7	R5Q	5	Missense	proximal	-2	no	17.875	17.797	PhosphoSitePlus	TCGA;ICGC;COSMIC	10.658	Down-regulation
Atypical_PIKK_ATR_ATR_ST	Q8IX01	SUGP2	Q13535	ATR	T7	F11V	11	Missense	distal	4	no	17.875	18.019	PhosphoSitePlus	TCGA;ICGC;COSMIC	10.658	Up-regulation
Atypical_PIKK_ATR_ATR_ST	Q8IX01	SUGP2	Q13535	ATR	T7	R4I	4	Missense	distal	-3	no	17.875	17.362	PhosphoSitePlus	TCGA;ICGC;COSMIC	10.658	Down-regulation
Atypical_PIKK_ATR_ATR_ST	Q8IX01	SUGP2	Q13535	ATR	T7	A2T	2	Missense	distal	-5	no	17.875	17.792	PhosphoSitePlus	TCGA;ICGC;COSMIC	10.658	Down-regulation
Atypical_PIKK_ATR_ATR_ST	Q8IX01	SUGP2	Q13535	ATR	S59	E52K	52	Missense	distal	-7	no	10.859	10.842	EPSD	TCGA;ICGC;COSMIC	10.658	Down-regulation
Atypical_PIKK_ATR_ATR_ST	Q8IX01	SUGP2	Q13535	ATR	S59	D55N	55	Missense	distal	-4	no	10.859	10.250	EPSD	TCGA;ICGC;COSMIC	10.658	Loss
Atypical_PIKK_ATR_ATR_ST	Q8IX01	SUGP2	Q13535	ATR	S133	D135G	135	Missense	proximal	2	no	12.685	14.232	EPSD	TCGA;ICGC;COSMIC	10.658	Up-regulation
Atypical_PIKK_ATR_ATR_ST	Q8IX01	SUGP2	Q13535	ATR	S133	L128S	128	Missense	distal	-5	no	12.685	12.503	EPSD	TCGA;ICGC	10.658	Down-regulation
Atypical_PIKK_ATR_ATR_ST	Q8IX01	SUGP2	Q13535	ATR	S143	R141C	141	Missense	proximal	-2	no	10.571	10.801	EPSD	TCGA;ICGC	10.658	Gain
Atypical_PIKK_ATR_ATR_ST	Q8IX01	SUGP2	Q13535	ATR	S153	E155K	155	Missense	proximal	2	no	14.834	13.885	EPSD	TCGA;ICGC;COSMIC	10.658	Down-regulation
Atypical_PIKK_ATR_ATR_ST	Q8IX01	SUGP2	Q13535	ATR	S159	E155K	155	Missense	distal	-4	no	13.745	13.334	EPSD	TCGA;ICGC;COSMIC	10.658	Down-regulation
Atypical_PIKK_ATR_ATR_ST	Q8IX01	SUGP2	Q13535	ATR	S159	P166L	166	Missense	distal	7	no	13.745	13.743	EPSD	TCGA;ICGC;COSMIC	10.658	Down-regulation
Atypical_PIKK_ATR_ATR_ST	Q8IX01	SUGP2	Q13535	ATR	S251	N249I	249	Missense	proximal	-2	no	10.692	10.340	EPSD	TCGA;ICGC;COSMIC	10.658	Loss
Atypical_PIKK_ATR_ATR_ST	Q8IX01	SUGP2	Q13535	ATR	S641	D648N	648	Missense	distal	7	no	10.875	11.099	EPSD	TCGA;ICGC;COSMIC	10.658	Up-regulation
Atypical_PIKK_ATR_ATR_ST	Q8IX01	SUGP2	Q13535	ATR	S641	R639W	639	Missense	proximal	-2	no	10.875	10.981	EPSD	TCGA;ICGC	10.658	Up-regulation
Atypical_PIKK_ATR_ATR_ST	Q8IX01	SUGP2	Q13535	ATR	S641	N643D	643	Missense	proximal	2	no	10.875	9.954	EPSD	TCGA;ICGC;COSMIC	10.658	Loss
Atypical_PIKK_ATR_ATR_ST	Q8IX01	SUGP2	Q13535	ATR	S721	K724N	724	Missense	distal	3	no	16.167	16.070	EPSD	TCGA;ICGC;COSMIC	10.658	Down-regulation
Atypical_PIKK_ATR_ATR_ST	Q8IX01	SUGP2	Q13535	ATR	S757	D764G	764	Missense	distal	7	no	12.725	12.534	EPSD	TCGA;ICGC;COSMIC	10.658	Down-regulation
Atypical_PIKK_ATR_ATR_ST	Q8IX01	SUGP2	Q13535	ATR	S757	K759E	759	Missense	proximal	2	no	12.725	13.674	EPSD	TCGA;ICGC;COSMIC	10.658	Up-regulation
Atypical_PIKK_ATR_ATR_ST	Q8IX01	SUGP2	Q13535	ATR	S860	G854D	854	Missense	distal	-6	no	11.580	11.613	EPSD	TCGA;ICGC;COSMIC	10.658	Up-regulation
Atypical_PIKK_ATR_ATR_ST	Q8IX01	SUGP2	Q13535	ATR	S860	V865M	865	Missense	distal	5	no	11.580	11.586	EPSD	TCGA;ICGC;COSMIC	10.658	Up-regulation
Atypical_PIKK_ATR_ATR_ST	Q8IX01	SUGP2	Q13535	ATR	S863	V865M	865	Missense	proximal	2	no	10.755	10.524	EPSD	TCGA;ICGC;COSMIC	10.658	Loss
Atypical_PIKK_ATR_ATR_ST	Q8IX01	SUGP2	Q13535	ATR	S887	E886Q	886	Missense	proximal	-1	no	13.117	13.032	EPSD	TCGA;COSMIC	10.658	Down-regulation
Atypical_PIKK_ATR_ATR_ST	Q8IX01	SUGP2	Q13535	ATR	S887	P880L	880	Missense	distal	-7	no	13.117	12.924	EPSD	TCGA;ICGC;COSMIC	10.658	Down-regulation
Atypical_PIKK_ATR_ATR_ST	Q8IX01	SUGP2	Q13535	ATR	S887	P892S	892	Missense	distal	5	no	13.117	13.105	EPSD	TCGA;ICGC;COSMIC	10.658	Down-regulation
Atypical_PIKK_ATR_ATR_ST	Q8IX01	SUGP2	Q13535	ATR	S940	S943F	943	Missense	distal	3	no	14.359	13.327	EPSD	TCGA;COSMIC	10.658	Down-regulation
Atypical_PIKK_ATR_ATR_ST	Q8IX01	SUGP2	Q13535	ATR	S1047	V1043M	1043	Missense	distal	-4	no	11.321	11.569	EPSD	TCGA;ICGC;COSMIC	10.658	Up-regulation
Atypical_PIKK_ATR_ATR_ST	Q8IX01	SUGP2	Q13535	ATR	S1047	S1047L	1047	Missense	central	0	yes	11.321	0.000	EPSD	TCGA;ICGC;COSMIC	10.658	Loss
Atypical_PIKK_ATR_ATR_ST	Q9H6E5	TUT1	Q13535	ATR	S112	G118E	118	Missense	distal	6	no	13.034	13.362	EPSD	TCGA;COSMIC	10.658	Up-regulation
Atypical_PIKK_ATR_ATR_ST	Q9H6E5	TUT1	Q13535	ATR	S238	S243C	243	Missense	distal	5	no	13.187	13.213	EPSD	TCGA;COSMIC	10.658	Up-regulation
Atypical_PIKK_ATR_ATR_ST	Q9H6E5	TUT1	Q13535	ATR	S240	S243C	243	Missense	distal	3	no	11.275	10.972	EPSD	TCGA;COSMIC	10.658	Down-regulation
Atypical_PIKK_ATR_ATR_ST	Q13315	ATM	Q13535	ATR	T86	K93N	93	Missense	distal	7	no	15.019	15.290	EPSD	TCGA;ICGC;COSMIC	10.658	Up-regulation
Atypical_PIKK_ATR_ATR_ST	Q13315	ATM	Q13535	ATR	T86	P80S	80	Missense	distal	-6	no	15.019	14.974	EPSD	TCGA;ICGC;COSMIC	10.658	Down-regulation
Atypical_PIKK_ATR_ATR_ST	Q13315	ATM	Q13535	ATR	S99	K93N	93	Missense	distal	-6	no	11.150	11.207	EPSD	TCGA;ICGC;COSMIC	10.658	Up-regulation
Atypical_PIKK_ATR_ATR_ST	Q13315	ATM	Q13535	ATR	S99	F104L	104	Missense	distal	5	no	11.150	11.144	EPSD	TCGA;ICGC	10.658	Down-regulation
Atypical_PIKK_ATR_ATR_ST	Q13315	ATM	Q13535	ATR	S99	L100W	100	Missense	proximal	1	no	11.150	9.661	EPSD	TCGA;ICGC;COSMIC	10.658	Loss
Atypical_PIKK_ATR_ATR_ST	Q13315	ATM	Q13535	ATR	S200	S207C	207	Missense	distal	7	no	13.414	13.776	EPSD	TCGA;ICGC;COSMIC	10.658	Up-regulation
Atypical_PIKK_ATR_ATR_ST	Q13315	ATM	Q13535	ATR	S200	G204R	204	Missense	distal	4	no	13.414	12.697	EPSD	TCGA;ICGC;COSMIC	10.658	Down-regulation
Atypical_PIKK_ATR_ATR_ST	Q13315	ATM	Q13535	ATR	T297	P292L	292	Missense	distal	-5	no	13.489	13.642	EPSD	TCGA;ICGC;COSMIC	10.658	Up-regulation
Atypical_PIKK_ATR_ATR_ST	Q13315	ATM	Q13535	ATR	T297	E299D	299	Missense	proximal	2	no	13.489	11.813	EPSD	TCGA;ICGC;COSMIC	10.658	Down-regulation
Atypical_PIKK_ATR_ATR_ST	Q13315	ATM	Q13535	ATR	T297	A295P	295	Missense	proximal	-2	no	13.489	12.765	EPSD	TCGA;ICGC;COSMIC	10.658	Down-regulation
Atypical_PIKK_ATR_ATR_ST	Q13315	ATM	Q13535	ATR	T297	H290Y	290	Missense	distal	-7	no	13.489	13.311	EPSD	TCGA;ICGC;COSMIC	10.658	Down-regulation
Atypical_PIKK_ATR_ATR_ST	Q13315	ATM	Q13535	ATR	T297	K296R	296	Missense	proximal	-1	no	13.489	13.723	EPSD	TCGA;ICGC	10.658	Up-regulation
Atypical_PIKK_ATR_ATR_ST	Q13315	ATM	Q13535	ATR	T297	G301S	301	Missense	distal	4	no	13.489	12.720	EPSD	TCGA;ICGC;COSMIC	10.658	Down-regulation
Atypical_PIKK_ATR_ATR_ST	Q13315	ATM	Q13535	ATR	S333	R329T	329	Missense	distal	-4	no	11.120	11.332	EPSD	TCGA;ICGC;COSMIC;CCLE	10.658	Up-regulation
Atypical_PIKK_ATR_ATR_ST	Q13315	ATM	Q13535	ATR	S333	R337H	337	Missense	distal	4	no	11.120	10.666	EPSD	TCGA;ICGC;COSMIC	10.658	Down-regulation
Atypical_PIKK_ATR_ATR_ST	Q13315	ATM	Q13535	ATR	S333	R337C	337	Missense	distal	4	no	11.120	11.757	EPSD	TCGA;ICGC;COSMIC;GDSC;CCLE	10.658	Up-regulation
Atypical_PIKK_ATR_ATR_ST	Q13315	ATM	Q13535	ATR	S333	G335E	335	Missense	proximal	2	no	11.120	11.250	EPSD	TCGA;ICGC;COSMIC	10.658	Up-regulation
Atypical_PIKK_ATR_ATR_ST	Q13315	ATM	Q13535	ATR	S333	S333Y	333	Missense	central	0	yes	11.120	0.000	EPSD	TCGA;ICGC	10.658	Loss
Atypical_PIKK_ATR_ATR_ST	Q13315	ATM	Q13535	ATR	S363	Q368E	368	Missense	distal	5	no	13.259	13.252	EPSD	TCGA;ICGC;COSMIC	10.658	Down-regulation
Atypical_PIKK_ATR_ATR_ST	Q13315	ATM	Q13535	ATR	S367	Q368E	368	Missense	proximal	1	no	10.982	5.062	EPSD	TCGA;ICGC;COSMIC	10.658	Loss
Atypical_PIKK_ATR_ATR_ST	Q13315	ATM	Q13535	ATR	T373	Q368E	368	Missense	distal	-5	no	14.349	14.175	EPSD	TCGA;ICGC;COSMIC	10.658	Down-regulation
Atypical_PIKK_ATR_ATR_ST	Q13315	ATM	Q13535	ATR	S440	S433Y	433	Missense	distal	-7	no	13.847	13.673	EPSD	TCGA;ICGC	10.658	Down-regulation
Atypical_PIKK_ATR_ATR_ST	Q13315	ATM	Q13535	ATR	S440	S440F	440	Missense	central	0	yes	13.847	0.000	EPSD	TCGA;ICGC	10.658	Loss
Atypical_PIKK_ATR_ATR_ST	Q13315	ATM	Q13535	ATR	S646	E642K	642	Missense	distal	-4	no	11.541	11.131	EPSD	TCGA;ICGC;COSMIC	10.658	Down-regulation
Atypical_PIKK_ATR_ATR_ST	Q13315	ATM	Q13535	ATR	S646	E649D	649	Missense	distal	3	no	11.541	11.431	EPSD	TCGA;ICGC;COSMIC	10.658	Down-regulation
Atypical_PIKK_ATR_ATR_ST	Q13315	ATM	Q13535	ATR	S1878	T1871I	1871	Missense	distal	-7	no	13.195	13.135	EPSD	TCGA;ICGC;COSMIC	10.658	Down-regulation
Atypical_PIKK_ATR_ATR_ST	Q13315	ATM	Q13535	ATR	S1878	R1882Q	1882	Missense	distal	4	no	13.195	13.029	EPSD	TCGA;ICGC;COSMIC	10.658	Down-regulation
Atypical_PIKK_ATR_ATR_ST	Q13315	ATM	Q13535	ATR	S1881	R1882Q	1882	Missense	proximal	1	no	5.096	12.091	EPSD	TCGA;ICGC;COSMIC	10.658	Gain
Atypical_PIKK_ATR_ATR_ST	Q13315	ATM	Q13535	ATR	S2162	E2164Q	2164	Missense	proximal	2	no	12.542	11.288	EPSD	TCGA;ICGC;COSMIC	10.658	Down-regulation
Atypical_PIKK_ATR_ATR_ST	Q13315	ATM	Q13535	ATR	S2162	E2164G	2164	Missense	proximal	2	no	12.542	12.412	EPSD	TCGA;ICGC;COSMIC	10.658	Down-regulation
Atypical_PIKK_ATR_ATR_ST	Q13315	ATM	Q13535	ATR	S2162	E2164K	2164	Missense	proximal	2	no	12.542	11.593	EPSD	TCGA;ICGC;COSMIC	10.658	Down-regulation
Atypical_PIKK_ATR_ATR_ST	Q13315	ATM	Q13535	ATR	S2162	S2168L	2168	Missense	distal	6	no	12.542	12.317	EPSD	TCGA;ICGC;COSMIC	10.658	Down-regulation
Atypical_PIKK_ATR_ATR_ST	Q13315	ATM	Q13535	ATR	S2242	E2238Q	2238	Missense	distal	-4	no	14.196	13.065	EPSD	TCGA;ICGC;COSMIC	10.658	Down-regulation
Atypical_PIKK_ATR_ATR_ST	Q13315	ATM	Q13535	ATR	S2592	R2598Q	2598	Missense	distal	6	no	13.565	13.834	EPSD	TCGA;ICGC;COSMIC	10.658	Up-regulation
Atypical_PIKK_ATR_ATR_ST	P16220	CREB1	Q13535	ATR	T100	S103A	103	Missense	distal	3	no	11.730	11.069	EPSD	TCGA;COSMIC	10.658	Down-regulation
Atypical_PIKK_ATR_ATR_ST	P16220	CREB1	Q13535	ATR	S111	D116G	116	Missense	distal	5	no	13.253	13.249	EPSD	TCGA;COSMIC	10.658	Down-regulation
Atypical_PIKK_ATR_ATR_ST	P16220	CREB1	Q13535	ATR	S111	Q112H	112	Missense	proximal	1	no	13.253	-4.265	EPSD	TCGA;COSMIC	10.658	Loss
Atypical_PIKK_ATR_ATR_ST	P16220	CREB1	Q13535	ATR	S121	D116G	116	Missense	distal	-5	no	16.403	16.250	PhosphoSitePlus	TCGA;COSMIC	10.658	Down-regulation
Atypical_PIKK_ATR_ATR_ST	P16220	CREB1	Q13535	ATR	S121	L128I	128	Missense	distal	7	no	16.403	16.561	PhosphoSitePlus	TCGA;COSMIC	10.658	Up-regulation
Atypical_PIKK_ATR_ATR_ST	O96017	CHEK2	Q13535	ATR	S19	S24C	24	Missense	distal	5	no	15.174	15.200	EPSD	TCGA;ICGC;COSMIC	10.658	Up-regulation
Atypical_PIKK_ATR_ATR_ST	O96017	CHEK2	Q13535	ATR	S19	C18S	18	Missense	proximal	-1	no	15.174	14.623	EPSD	TCGA;ICGC;COSMIC	10.658	Down-regulation
Atypical_PIKK_ATR_ATR_ST	O96017	CHEK2	Q13535	ATR	S19	S16R	16	Missense	distal	-3	no	15.174	15.711	EPSD	TCGA;ICGC;COSMIC	10.658	Up-regulation
Atypical_PIKK_ATR_ATR_ST	O96017	CHEK2	Q13535	ATR	S28	S24C	24	Missense	distal	-4	no	13.836	12.547	EPSD	TCGA;ICGC;COSMIC	10.658	Down-regulation
Atypical_PIKK_ATR_ATR_ST	O96017	CHEK2	Q13535	ATR	S35	S42C	42	Missense	distal	7	no	15.081	15.443	EPSD	TCGA;ICGC;COSMIC	10.658	Up-regulation
Atypical_PIKK_ATR_ATR_ST	O96017	CHEK2	Q13535	ATR	S50	S53F	53	Missense	distal	3	no	15.918	14.886	EPSD	TCGA;ICGC;COSMIC	10.658	Down-regulation
Atypical_PIKK_ATR_ATR_ST	O96017	CHEK2	Q13535	ATR	S50	S56R	56	Missense	distal	6	no	15.918	15.521	EPSD	TCGA;ICGC;COSMIC	10.658	Down-regulation
Atypical_PIKK_ATR_ATR_ST	O96017	CHEK2	Q13535	ATR	T68	E70G	70	Missense	proximal	2	no	14.803	14.674	PhosphoSitePlus	TCGA	10.658	Down-regulation
Atypical_PIKK_ATR_ATR_ST	O96017	CHEK2	Q13535	ATR	S357	E351Q	351	Missense	distal	-6	no	12.798	12.816	EPSD	TCGA;COSMIC	10.658	Up-regulation
Atypical_PIKK_ATR_ATR_ST	Q13535	ATR	Q13535	ATR	S61	S61C	61	Missense	central	0	yes	13.209	0.000	EPSD	TCGA;ICGC;COSMIC	10.658	Loss
Atypical_PIKK_ATR_ATR_ST	Q13535	ATR	Q13535	ATR	S61	E54Q	54	Missense	distal	-7	no	13.209	13.164	EPSD	TCGA;ICGC;COSMIC	10.658	Down-regulation
Atypical_PIKK_ATR_ATR_ST	Q13535	ATR	Q13535	ATR	S61	V66M	66	Missense	distal	5	no	13.209	13.216	EPSD	TCGA;ICGC;COSMIC	10.658	Up-regulation
Atypical_PIKK_ATR_ATR_ST	Q13535	ATR	Q13535	ATR	S61	V66L	66	Missense	distal	5	no	13.209	13.214	EPSD	TCGA;ICGC;COSMIC	10.658	Up-regulation
Atypical_PIKK_ATR_ATR_ST	Q13535	ATR	Q13535	ATR	S428	R432C	432	Missense	distal	4	no	12.064	12.701	EPSD	TCGA;COSMIC	10.658	Up-regulation
Atypical_PIKK_ATR_ATR_ST	Q13535	ATR	Q13535	ATR	S428	G426R	426	Missense	proximal	-2	no	12.064	12.160	EPSD	TCGA;ICGC;COSMIC	10.658	Up-regulation
Atypical_PIKK_ATR_ATR_ST	Q13535	ATR	Q13535	ATR	S428	P429L	429	Missense	proximal	1	no	12.064	11.498	EPSD	TCGA;ICGC;COSMIC	10.658	Down-regulation
Atypical_PIKK_ATR_ATR_ST	Q13535	ATR	Q13535	ATR	S428	R433H	433	Missense	distal	5	no	12.064	12.058	EPSD	TCGA;ICGC;COSMIC	10.658	Down-regulation
Atypical_PIKK_ATR_ATR_ST	Q13535	ATR	Q13535	ATR	S1154	D1147N	1147	Missense	distal	-7	no	12.269	12.150	EPSD	TCGA;COSMIC	10.658	Down-regulation
Atypical_PIKK_ATR_ATR_ST	Q13535	ATR	Q13535	ATR	S1154	M1159L	1159	Missense	distal	5	no	12.269	12.267	EPSD	TCGA;COSMIC	10.658	Down-regulation
Atypical_PIKK_ATR_ATR_ST	Q13535	ATR	Q13535	ATR	T1566	D1559E	1559	Missense	distal	-7	no	12.550	12.596	EPSD	TCGA;COSMIC	10.658	Up-regulation
Atypical_PIKK_ATR_ATR_ST	Q13535	ATR	Q13535	ATR	T1566	D1560N	1560	Missense	distal	-6	no	12.550	12.553	EPSD	TCGA;COSMIC	10.658	Up-regulation
Atypical_PIKK_ATR_ATR_ST	Q13535	ATR	Q13535	ATR	T1566	N1565D	1565	Missense	proximal	-1	no	12.550	12.260	EPSD	TCGA;COSMIC	10.658	Down-regulation
Atypical_PIKK_ATR_ATR_ST	Q13535	ATR	Q13535	ATR	T1578	S1583C	1583	Missense	distal	5	no	12.280	12.306	EPSD	TCGA;ICGC;COSMIC	10.658	Up-regulation
Atypical_PIKK_ATR_ATR_ST	Q13535	ATR	Q13535	ATR	T1578	S1583F	1583	Missense	distal	5	no	12.280	12.292	EPSD	TCGA;ICGC;COSMIC	10.658	Up-regulation
Atypical_PIKK_ATR_ATR_ST	Q13535	ATR	Q13535	ATR	T1578	L1576R	1576	Missense	proximal	-2	no	12.280	11.987	EPSD	TCGA;COSMIC	10.658	Down-regulation
Atypical_PIKK_ATR_ATR_ST	Q13535	ATR	Q13535	ATR	T1589	S1583C	1583	Missense	distal	-6	no	14.249	14.319	EPSD	TCGA;ICGC;COSMIC	10.658	Up-regulation
Atypical_PIKK_ATR_ATR_ST	Q13535	ATR	Q13535	ATR	T1589	K1595T	1595	Missense	distal	6	no	14.249	14.317	EPSD	TCGA;ICGC;COSMIC	10.658	Up-regulation
Atypical_PIKK_ATR_ATR_ST	Q13535	ATR	Q13535	ATR	T1589	S1583F	1583	Missense	distal	-6	no	14.249	14.329	EPSD	TCGA;ICGC;COSMIC	10.658	Up-regulation
Atypical_PIKK_ATR_ATR_ST	Q13535	ATR	Q13535	ATR	S1876	D1879N	1879	Missense	distal	3	no	11.526	11.696	EPSD	TCGA;ICGC;COSMIC	10.658	Up-regulation
Atypical_PIKK_ATR_ATR_ST	Q13535	ATR	Q13535	ATR	T1890	S1893F	1893	Missense	distal	3	no	13.617	12.586	EPSD	TCGA;COSMIC	10.658	Down-regulation
Atypical_PIKK_ATR_ATR_ST	Q13535	ATR	Q13535	ATR	T1989	P1985S	1985	Missense	distal	-4	no	11.074	10.749	PhosphoSitePlus	TCGA;ICGC;COSMIC	10.658	Down-regulation
Atypical_PIKK_ATR_ATR_ST	P35568	IRS1	Q13535	ATR	S24	R20C	20	Missense	distal	-4	no	11.040	10.049	EPSD	TCGA;ICGC;COSMIC	10.658	Loss
Atypical_PIKK_ATR_ATR_ST	P35568	IRS1	Q13535	ATR	S24	R20H	20	Missense	distal	-4	no	11.040	11.041	EPSD	TCGA;ICGC	10.658	Up-regulation
Atypical_PIKK_ATR_ATR_ST	P35568	IRS1	Q13535	ATR	T88	R89Q	89	Missense	proximal	1	no	9.682	16.677	EPSD	TCGA;COSMIC	10.658	Gain
Atypical_PIKK_ATR_ATR_ST	P35568	IRS1	Q13535	ATR	S99	I95M	95	Missense	distal	-4	no	10.841	11.964	EPSD	TCGA;ICGC;COSMIC	10.658	Up-regulation
Atypical_PIKK_ATR_ATR_ST	P35568	IRS1	Q13535	ATR	S99	H92Q	92	Missense	distal	-7	no	10.841	10.821	EPSD	TCGA;ICGC	10.658	Down-regulation
Atypical_PIKK_ATR_ATR_ST	P35568	IRS1	Q13535	ATR	S270	E263K	263	Missense	distal	-7	no	14.440	14.423	PhosphoSitePlus	TCGA;ICGC;COSMIC	10.658	Down-regulation
Atypical_PIKK_ATR_ATR_ST	P35568	IRS1	Q13535	ATR	S270	K269N	269	Missense	proximal	-1	no	14.440	15.024	PhosphoSitePlus	TCGA;ICGC;COSMIC	10.658	Up-regulation
Atypical_PIKK_ATR_ATR_ST	P35568	IRS1	Q13535	ATR	S270	P266S	266	Missense	distal	-4	no	14.440	14.115	PhosphoSitePlus	TCGA;ICGC;COSMIC	10.658	Down-regulation
Atypical_PIKK_ATR_ATR_ST	P35568	IRS1	Q13535	ATR	S270	C276F	276	Missense	distal	6	no	14.440	14.465	PhosphoSitePlus	TCGA;ICGC;COSMIC	10.658	Up-regulation
Atypical_PIKK_ATR_ATR_ST	P35568	IRS1	Q13535	ATR	S270	N275S	275	Missense	distal	5	no	14.440	14.435	PhosphoSitePlus	TCGA;ICGC;COSMIC	10.658	Down-regulation
Atypical_PIKK_ATR_ATR_ST	P35568	IRS1	Q13535	ATR	S277	C276F	276	Missense	proximal	-1	no	14.052	13.503	EPSD	TCGA;ICGC;COSMIC	10.658	Down-regulation
Atypical_PIKK_ATR_ATR_ST	P35568	IRS1	Q13535	ATR	S277	N275S	275	Missense	proximal	-2	no	14.052	13.204	EPSD	TCGA;ICGC;COSMIC	10.658	Down-regulation
Atypical_PIKK_ATR_ATR_ST	P35568	IRS1	Q13535	ATR	S315	A314G	314	Missense	proximal	-1	no	10.769	10.586	EPSD	TCGA;ICGC;COSMIC	10.658	Loss
Atypical_PIKK_ATR_ATR_ST	P35568	IRS1	Q13535	ATR	S315	P321L	321	Missense	distal	6	no	10.769	10.842	EPSD	TCGA;ICGC;COSMIC	10.658	Up-regulation
Atypical_PIKK_ATR_ATR_ST	P35568	IRS1	Q13535	ATR	S345	R338H	338	Missense	distal	-7	no	11.532	11.584	EPSD	TCGA;ICGC;COSMIC	10.658	Up-regulation
Atypical_PIKK_ATR_ATR_ST	P35568	IRS1	Q13535	ATR	S345	R338C	338	Missense	distal	-7	no	11.532	11.355	EPSD	TCGA;ICGC;COSMIC	10.658	Down-regulation
Atypical_PIKK_ATR_ATR_ST	P35568	IRS1	Q13535	ATR	S345	P346H	346	Missense	proximal	1	no	11.532	-1.118	EPSD	TCGA;ICGC	10.658	Loss
Atypical_PIKK_ATR_ATR_ST	P35568	IRS1	Q13535	ATR	T397	S395C	395	Missense	proximal	-2	no	10.745	11.384	EPSD	TCGA;ICGC;COSMIC	10.658	Up-regulation
Atypical_PIKK_ATR_ATR_ST	P35568	IRS1	Q13535	ATR	S449	V445I	445	Missense	distal	-4	no	13.391	12.517	EPSD	TCGA;ICGC;COSMIC	10.658	Down-regulation
Atypical_PIKK_ATR_ATR_ST	P35568	IRS1	Q13535	ATR	S449	R443H	443	Missense	distal	-6	no	13.391	13.397	EPSD	TCGA;ICGC	10.658	Up-regulation
Atypical_PIKK_ATR_ATR_ST	P35568	IRS1	Q13535	ATR	S463	G469C	469	Missense	distal	6	no	13.218	13.277	EPSD	TCGA;ICGC;COSMIC	10.658	Up-regulation
Atypical_PIKK_ATR_ATR_ST	P35568	IRS1	Q13535	ATR	S463	E461G	461	Missense	proximal	-2	no	13.218	13.235	EPSD	TCGA;ICGC;COSMIC	10.658	Up-regulation
Atypical_PIKK_ATR_ATR_ST	P35568	IRS1	Q13535	ATR	S547	S544L	544	Missense	distal	-3	no	11.112	11.683	EPSD	TCGA;ICGC;COSMIC	10.658	Up-regulation
Atypical_PIKK_ATR_ATR_ST	P35568	IRS1	Q13535	ATR	S547	E553D	553	Missense	distal	6	no	11.112	10.838	EPSD	TCGA;ICGC;COSMIC	10.658	Down-regulation
Atypical_PIKK_ATR_ATR_ST	P35568	IRS1	Q13535	ATR	S694	V689F	689	Missense	distal	-5	no	10.973	11.101	EPSD	TCGA;ICGC;COSMIC	10.658	Up-regulation
Atypical_PIKK_ATR_ATR_ST	P35568	IRS1	Q13535	ATR	S694	P690H	690	Missense	distal	-4	no	10.973	10.351	EPSD	TCGA	10.658	Loss
Atypical_PIKK_ATR_ATR_ST	P35568	IRS1	Q13535	ATR	S741	N742D	742	Missense	proximal	1	no	10.880	9.742	EPSD	TCGA;ICGC;COSMIC	10.658	Loss
Atypical_PIKK_ATR_ATR_ST	P35568	IRS1	Q13535	ATR	S892	P890S	890	Missense	proximal	-2	no	11.774	11.722	EPSD	TCGA;ICGC;COSMIC	10.658	Down-regulation
Atypical_PIKK_ATR_ATR_ST	P35568	IRS1	Q13535	ATR	T938	E939Q	939	Missense	proximal	1	no	6.817	12.738	EPSD	TCGA;ICGC;COSMIC	10.658	Gain
Atypical_PIKK_ATR_ATR_ST	P35568	IRS1	Q13535	ATR	T1004	S1005L	1005	Missense	proximal	1	no	11.315	11.858	EPSD	TCGA;ICGC	10.658	Up-regulation
Atypical_PIKK_ATR_ATR_ST	P35568	IRS1	Q13535	ATR	S1078	R1081H	1081	Missense	distal	3	no	10.445	10.853	EPSD	TCGA;ICGC;COSMIC	10.658	Gain
Atypical_PIKK_ATR_ATR_ST	P35568	IRS1	Q13535	ATR	S1131	S1133N	1133	Missense	proximal	2	no	10.394	10.707	EPSD	TCGA;ICGC	10.658	Gain
Atypical_PIKK_ATR_ATR_ST	P35568	IRS1	Q13535	ATR	S1134	S1133N	1133	Missense	proximal	-1	no	10.245	10.723	EPSD	TCGA;ICGC	10.658	Gain
Atypical_PIKK_ATR_ATR_ST	O75943	RAD17	Q13535	ATR	T304	N308D	308	Missense	distal	4	no	11.033	10.344	EPSD	TCGA;ICGC;COSMIC	10.658	Loss
Atypical_PIKK_ATR_ATR_ST	O75943	RAD17	Q13535	ATR	T304	R301Q	301	Missense	distal	-3	no	11.033	10.849	EPSD	TCGA	10.658	Down-regulation
Atypical_PIKK_ATR_ATR_ST	O75943	RAD17	Q13535	ATR	S646	L643I	643	Missense	distal	-3	no	17.814	17.266	EPSD;PhosphoSitePlus	TCGA;COSMIC	10.658	Down-regulation
Atypical_PIKK_ATR_ATR_ST	O75943	RAD17	Q13535	ATR	S646	P644S	644	Missense	proximal	-2	no	17.814	17.762	EPSD;PhosphoSitePlus	TCGA;COSMIC	10.658	Down-regulation
Atypical_PIKK_ATR_ATR_ST	O75943	RAD17	Q13535	ATR	S646	S642F	642	Missense	distal	-4	no	17.814	17.530	EPSD;PhosphoSitePlus	TCGA	10.658	Down-regulation
Atypical_PIKK_ATR_ATR_ST	O75943	RAD17	Q13535	ATR	S656	F661C	661	Missense	distal	5	no	20.318	20.332	PhosphoSitePlus;EPSD	TCGA	10.658	Up-regulation
Atypical_PIKK_ATR_ATR_ST	Q14191	WRN	Q13535	ATR	T174	K168Q	168	Missense	distal	-6	no	10.610	10.675	EPSD	TCGA;ICGC	10.658	Gain
Atypical_PIKK_ATR_ATR_ST	Q14191	WRN	Q13535	ATR	S176	V181A	181	Missense	distal	5	no	10.842	10.852	EPSD	TCGA;ICGC;COSMIC	10.658	Up-regulation
Atypical_PIKK_ATR_ATR_ST	Q14191	WRN	Q13535	ATR	S409	L405V	405	Missense	distal	-4	no	13.933	14.340	EPSD	TCGA;ICGC;COSMIC	10.658	Up-regulation
Atypical_PIKK_ATR_ATR_ST	Q14191	WRN	Q13535	ATR	S462	D468E	468	Missense	distal	6	no	10.649	10.924	EPSD	TCGA;ICGC;COSMIC	10.658	Gain
Atypical_PIKK_ATR_ATR_ST	Q14191	WRN	Q13535	ATR	S478	E480D	480	Missense	proximal	2	no	12.861	11.185	EPSD	TCGA;ICGC	10.658	Down-regulation
Atypical_PIKK_ATR_ATR_ST	Q14191	WRN	Q13535	ATR	S478	S484R	484	Missense	distal	6	no	12.861	12.464	EPSD	TCGA;ICGC;COSMIC	10.658	Down-regulation
Atypical_PIKK_ATR_ATR_ST	Q14191	WRN	Q13535	ATR	S612	P615L	615	Missense	distal	3	no	10.833	10.230	EPSD	TCGA;ICGC;COSMIC	10.658	Loss
Atypical_PIKK_ATR_ATR_ST	Q14191	WRN	Q13535	ATR	S1058	L1063F	1063	Missense	distal	5	no	14.323	14.329	EPSD	TCGA;ICGC;COSMIC	10.658	Up-regulation
Atypical_PIKK_ATR_ATR_ST	Q14191	WRN	Q13535	ATR	S1139	S1140P	1140	Missense	proximal	1	no	9.889	10.999	EPSD	TCGA;ICGC;COSMIC	10.658	Gain
Atypical_PIKK_ATR_ATR_ST	Q14191	WRN	Q13535	ATR	S1141	S1140P	1140	Missense	proximal	-1	no	16.282	16.497	PhosphoSitePlus	TCGA;ICGC;COSMIC	10.658	Up-regulation
Atypical_PIKK_ATR_ATR_ST	Q14191	WRN	Q13535	ATR	S1292	S1292F	1292	Missense	central	0	yes	14.128	0.000	EPSD	TCGA;ICGC;COSMIC	10.658	Loss
Atypical_PIKK_ATR_ATR_ST	Q14191	WRN	Q13535	ATR	S1292	A1294V	1294	Missense	proximal	2	no	14.128	14.618	EPSD	TCGA;ICGC;COSMIC	10.658	Up-regulation
Atypical_PIKK_ATR_ATR_ST	Q14191	WRN	Q13535	ATR	S1378	S1378F	1378	Missense	central	0	yes	11.754	0.000	EPSD	TCGA;ICGC;COSMIC	10.658	Loss
Atypical_PIKK_ATR_ATR_ST	Q14191	WRN	Q13535	ATR	S1378	R1373I	1373	Missense	distal	-5	no	11.754	11.776	EPSD	TCGA;ICGC;COSMIC	10.658	Up-regulation
Atypical_PIKK_ATR_ATR_ST	P49736	MCM2	Q13535	ATR	S13	T9I	9	Missense	distal	-4	no	11.448	10.192	EPSD	TCGA;ICGC;COSMIC	10.658	Loss
Atypical_PIKK_ATR_ATR_ST	P49736	MCM2	Q13535	ATR	T39	D36N	36	Missense	distal	-3	no	11.507	11.799	EPSD	TCGA;ICGC;COSMIC	10.658	Up-regulation
Atypical_PIKK_ATR_ATR_ST	P49736	MCM2	Q13535	ATR	T39	L38I	38	Missense	proximal	-1	no	11.507	11.544	EPSD	TCGA;ICGC;COSMIC	10.658	Up-regulation
Atypical_PIKK_ATR_ATR_ST	P49736	MCM2	Q13535	ATR	S41	D36N	36	Missense	distal	-5	no	13.128	13.101	EPSD	TCGA;ICGC;COSMIC	10.658	Down-regulation
Atypical_PIKK_ATR_ATR_ST	P49736	MCM2	Q13535	ATR	S41	L38I	38	Missense	distal	-3	no	13.128	12.580	EPSD	TCGA;ICGC;COSMIC	10.658	Down-regulation
Atypical_PIKK_ATR_ATR_ST	P49736	MCM2	Q13535	ATR	S108	E111G	111	Missense	distal	3	no	15.987	15.808	PhosphoSitePlus	TCGA;ICGC;COSMIC	10.658	Down-regulation
Atypical_PIKK_ATR_ATR_ST	P49736	MCM2	Q13535	ATR	S170	E165K	165	Missense	distal	-5	no	11.079	11.160	EPSD	TCGA;ICGC;COSMIC	10.658	Up-regulation
Atypical_PIKK_ATR_ATR_ST	P49736	MCM2	Q13535	ATR	S170	E175K	175	Missense	distal	5	no	11.079	11.088	EPSD	TCGA;ICGC;COSMIC	10.658	Up-regulation
Atypical_PIKK_ATR_ATR_ST	P49736	MCM2	Q13535	ATR	S229	E225D	225	Missense	distal	-4	no	13.304	13.121	EPSD	TCGA;ICGC;COSMIC	10.658	Down-regulation
Atypical_PIKK_ATR_ATR_ST	P49736	MCM2	Q13535	ATR	S769	R765W	765	Missense	distal	-4	no	10.684	11.142	EPSD	TCGA;ICGC;COSMIC	10.658	Up-regulation
Atypical_PIKK_ATR_ATR_ST	P49736	MCM2	Q13535	ATR	T805	R812C	812	Missense	distal	7	no	13.074	13.212	EPSD	TCGA;ICGC;COSMIC;GDSC;CCLE	10.658	Up-regulation
Atypical_PIKK_ATR_ATR_ST	P49736	MCM2	Q13535	ATR	T805	R812H	812	Missense	distal	7	no	13.074	13.103	EPSD	TCGA;ICGC	10.658	Up-regulation
Atypical_PIKK_ATR_ATR_ST	O15360	FANCA	Q13535	ATR	T381	Q382H	382	Missense	proximal	1	no	13.731	-3.787	EPSD	TCGA;ICGC;COSMIC	10.658	Loss
Atypical_PIKK_ATR_ATR_ST	O15360	FANCA	Q13535	ATR	T381	E380G	380	Missense	proximal	-1	no	13.731	13.683	EPSD	TCGA;ICGC;COSMIC	10.658	Down-regulation
Atypical_PIKK_ATR_ATR_ST	O15360	FANCA	Q13535	ATR	T589	A586T	586	Missense	distal	-3	no	10.940	10.378	EPSD	TCGA;ICGC;COSMIC	10.658	Loss
Atypical_PIKK_ATR_ATR_ST	O15360	FANCA	Q13535	ATR	T589	R591Q	591	Missense	proximal	2	no	10.940	11.029	EPSD	TCGA;ICGC;COSMIC	10.658	Up-regulation
Atypical_PIKK_ATR_ATR_ST	O15360	FANCA	Q13535	ATR	S599	A602V	602	Missense	distal	3	no	9.948	10.708	EPSD	TCGA;ICGC;COSMIC;CCLE	10.658	Gain
Atypical_PIKK_ATR_ATR_ST	O15360	FANCA	Q13535	ATR	T1309	E1310Q	1310	Missense	proximal	1	no	6.975	12.896	EPSD	TCGA;ICGC;COSMIC	10.658	Gain
Atypical_PIKK_ATR_ATR_ST	O15360	FANCA	Q13535	ATR	S1449	A1446T	1446	Missense	distal	-3	no	16.222	15.661	PhosphoSitePlus	TCGA;ICGC;COSMIC	10.658	Down-regulation
Atypical_PIKK_ATR_ATR_ST	Q9UER7	DAXX	Q13535	ATR	S41	A47V	47	Missense	distal	6	no	11.270	11.483	EPSD	TCGA;ICGC;COSMIC	10.658	Up-regulation
Atypical_PIKK_ATR_ATR_ST	Q9UER7	DAXX	Q13535	ATR	S41	S41F	41	Missense	central	0	yes	11.270	0.000	EPSD	TCGA;ICGC;COSMIC	10.658	Loss
Atypical_PIKK_ATR_ATR_ST	Q9UER7	DAXX	Q13535	ATR	S50	K57E	57	Missense	distal	7	no	10.734	10.585	EPSD	TCGA	10.658	Loss
Atypical_PIKK_ATR_ATR_ST	Q9UER7	DAXX	Q13535	ATR	S50	A47V	47	Missense	distal	-3	no	10.734	10.335	EPSD	TCGA;ICGC;COSMIC	10.658	Loss
Atypical_PIKK_ATR_ATR_ST	Q9UER7	DAXX	Q13535	ATR	S50	G55S	55	Missense	distal	5	no	10.734	10.728	EPSD	TCGA;ICGC;COSMIC	10.658	Down-regulation
Atypical_PIKK_ATR_ATR_ST	Q9UER7	DAXX	Q13535	ATR	S50	K56N	56	Missense	distal	6	no	10.734	10.962	EPSD	TCGA;ICGC;COSMIC	10.658	Up-regulation
Atypical_PIKK_ATR_ATR_ST	Q9UER7	DAXX	Q13535	ATR	S51	K57E	57	Missense	distal	6	no	11.875	12.075	EPSD	TCGA	10.658	Up-regulation
Atypical_PIKK_ATR_ATR_ST	Q9UER7	DAXX	Q13535	ATR	S51	A47V	47	Missense	distal	-4	no	11.875	10.886	EPSD	TCGA;ICGC;COSMIC	10.658	Down-regulation
Atypical_PIKK_ATR_ATR_ST	Q9UER7	DAXX	Q13535	ATR	S51	G55S	55	Missense	distal	4	no	11.875	11.106	EPSD	TCGA;ICGC;COSMIC	10.658	Down-regulation
Atypical_PIKK_ATR_ATR_ST	Q9UER7	DAXX	Q13535	ATR	S51	K56N	56	Missense	distal	5	no	11.875	11.876	EPSD	TCGA;ICGC;COSMIC	10.658	Up-regulation
Atypical_PIKK_ATR_ATR_ST	Q9UER7	DAXX	Q13535	ATR	T151	P155S	155	Missense	distal	4	no	11.622	11.535	EPSD	TCGA;ICGC;COSMIC	10.658	Down-regulation
Atypical_PIKK_ATR_ATR_ST	Q9UER7	DAXX	Q13535	ATR	T151	A149V	149	Missense	proximal	-2	no	11.622	11.102	EPSD	TCGA;ICGC	10.658	Down-regulation
Atypical_PIKK_ATR_ATR_ST	Q9UER7	DAXX	Q13535	ATR	S152	P155S	155	Missense	distal	3	no	10.953	11.017	EPSD	TCGA;ICGC;COSMIC	10.658	Up-regulation
Atypical_PIKK_ATR_ATR_ST	Q9UER7	DAXX	Q13535	ATR	S152	A149V	149	Missense	distal	-3	no	10.953	10.554	EPSD	TCGA;ICGC	10.658	Loss
Atypical_PIKK_ATR_ATR_ST	Q9UER7	DAXX	Q13535	ATR	S176	E172K	172	Missense	distal	-4	no	13.958	13.547	EPSD	TCGA;ICGC;COSMIC;CCLE	10.658	Down-regulation
Atypical_PIKK_ATR_ATR_ST	Q9UER7	DAXX	Q13535	ATR	S176	S176C	176	Missense	central	0	yes	13.958	0.000	EPSD	TCGA;ICGC;COSMIC	10.658	Loss
Atypical_PIKK_ATR_ATR_ST	Q9UER7	DAXX	Q13535	ATR	S176	R180M	180	Missense	distal	4	no	13.958	13.461	EPSD	TCGA;ICGC	10.658	Down-regulation
Atypical_PIKK_ATR_ATR_ST	Q9UER7	DAXX	Q13535	ATR	S176	A175T	175	Missense	proximal	-1	no	13.958	13.728	EPSD	TCGA;ICGC	10.658	Down-regulation
Atypical_PIKK_ATR_ATR_ST	Q9UER7	DAXX	Q13535	ATR	S424	G421E	421	Missense	distal	-3	no	17.001	17.160	PhosphoSitePlus	TCGA;ICGC;COSMIC	10.658	Up-regulation
Atypical_PIKK_ATR_ATR_ST	Q9UER7	DAXX	Q13535	ATR	S564	L566F	566	Missense	proximal	2	no	11.829	10.107	EPSD	TCGA;ICGC;COSMIC	10.658	Loss
Atypical_PIKK_ATR_ATR_ST	Q9UER7	DAXX	Q13535	ATR	S564	P562L	562	Missense	proximal	-2	no	11.829	12.480	EPSD	TCGA;ICGC;COSMIC	10.658	Up-regulation
Atypical_PIKK_ATR_ATR_ST	Q9UER7	DAXX	Q13535	ATR	S588	S588F	588	Missense	central	0	yes	10.670	0.000	EPSD	TCGA;ICGC;COSMIC;CCLE	10.658	Loss
Atypical_PIKK_ATR_ATR_ST	Q9UER7	DAXX	Q13535	ATR	S588	S587P	587	Missense	proximal	-1	no	10.670	10.885	EPSD	TCGA;ICGC;COSMIC	10.658	Up-regulation
Atypical_PIKK_ATR_ATR_ST	Q9UER7	DAXX	Q13535	ATR	S588	S588Y	588	Missense	central	0	yes	10.670	0.000	EPSD	TCGA;ICGC;COSMIC	10.658	Loss
Atypical_PIKK_ATR_ATR_ST	Q9UER7	DAXX	Q13535	ATR	S588	S587F	587	Missense	proximal	-1	no	10.670	10.672	EPSD	TCGA;ICGC;COSMIC	10.658	Up-regulation
Atypical_PIKK_ATR_ATR_ST	Q9UER7	DAXX	Q13535	ATR	S618	S612T	612	Missense	distal	-6	no	11.540	11.626	EPSD	TCGA;ICGC	10.658	Up-regulation
Atypical_PIKK_ATR_ATR_ST	Q9UER7	DAXX	Q13535	ATR	T665	P667L	667	Missense	proximal	2	no	10.695	9.413	EPSD	TCGA;ICGC;COSMIC	10.658	Loss
Atypical_PIKK_ATR_ATR_ST	Q9UER7	DAXX	Q13535	ATR	T665	K658N	658	Missense	distal	-7	no	10.695	10.548	EPSD	TCGA;ICGC	10.658	Loss
Atypical_PIKK_ATR_ATR_ST	Q9UER7	DAXX	Q13535	ATR	T665	C664F	664	Missense	proximal	-1	no	10.695	10.145	EPSD	TCGA;ICGC;COSMIC	10.658	Loss
Atypical_PIKK_ATR_ATR_ST	Q9UER7	DAXX	Q13535	ATR	T665	S671F	671	Missense	distal	6	no	10.695	10.536	EPSD	TCGA;ICGC;COSMIC	10.658	Loss
Atypical_PIKK_ATR_ATR_ST	Q9UER7	DAXX	Q13535	ATR	T665	K662N	662	Missense	distal	-3	no	10.695	11.855	EPSD	TCGA;ICGC;COSMIC	10.658	Up-regulation
Atypical_PIKK_ATR_ATR_ST	Q9UER7	DAXX	Q13535	ATR	T665	G660E	660	Missense	distal	-5	no	10.695	10.595	EPSD	TCGA;ICGC	10.658	Loss
Atypical_PIKK_ATR_ATR_ST	Q9UER7	DAXX	Q13535	ATR	T684	R685M	685	Missense	proximal	1	no	7.843	10.753	EPSD	TCGA;ICGC	10.658	Gain
Atypical_PIKK_ATR_ATR_ST	Q9UER7	DAXX	Q13535	ATR	S688	S682C	682	Missense	distal	-6	no	11.222	11.291	EPSD	TCGA;ICGC;COSMIC	10.658	Up-regulation
Atypical_PIKK_ATR_ATR_ST	Q9UER7	DAXX	Q13535	ATR	S688	R685M	685	Missense	distal	-3	no	11.222	10.700	EPSD	TCGA;ICGC	10.658	Down-regulation
Atypical_PIKK_ATR_ATR_ST	Q9UER7	DAXX	Q13535	ATR	S707	P701L	701	Missense	distal	-6	no	10.780	10.844	EPSD	TCGA;ICGC;COSMIC	10.658	Up-regulation
Atypical_PIKK_ATR_ATR_ST	Q9UER7	DAXX	Q13535	ATR	S707	S702F	702	Missense	distal	-5	no	10.780	11.007	EPSD	TCGA;ICGC;COSMIC	10.658	Up-regulation
Atypical_PIKK_ATR_ATR_ST	Q9UER7	DAXX	Q13535	ATR	T726	D729N	729	Missense	distal	3	no	12.988	13.157	EPSD	TCGA;ICGC;COSMIC	10.658	Up-regulation
Atypical_PIKK_ATR_ATR_ST	Q03164	KMT2A	Q13535	ATR	S153	V157I	157	Missense	distal	4	no	10.699	11.219	EPSD	TCGA;ICGC;COSMIC	10.658	Up-regulation
Atypical_PIKK_ATR_ATR_ST	Q03164	KMT2A	Q13535	ATR	S153	S153L	153	Missense	central	0	yes	10.699	0.000	EPSD	TCGA;ICGC;COSMIC	10.658	Loss
Atypical_PIKK_ATR_ATR_ST	Q03164	KMT2A	Q13535	ATR	S153	F148L	148	Missense	distal	-5	no	10.699	10.655	EPSD	TCGA;ICGC;COSMIC	10.658	Loss
Atypical_PIKK_ATR_ATR_ST	Q03164	KMT2A	Q13535	ATR	S252	K254N	254	Missense	proximal	2	no	12.089	12.283	EPSD	TCGA;ICGC;COSMIC	10.658	Up-regulation
Atypical_PIKK_ATR_ATR_ST	Q03164	KMT2A	Q13535	ATR	S252	K254Q	254	Missense	proximal	2	no	12.089	11.785	EPSD	TCGA;ICGC;COSMIC	10.658	Down-regulation
Atypical_PIKK_ATR_ATR_ST	Q03164	KMT2A	Q13535	ATR	S279	S279F	279	Missense	central	0	yes	12.300	0.000	EPSD	TCGA;ICGC;COSMIC	10.658	Loss
Atypical_PIKK_ATR_ATR_ST	Q03164	KMT2A	Q13535	ATR	S279	P280L	280	Missense	proximal	1	no	12.300	11.734	EPSD	TCGA;ICGC;COSMIC	10.658	Down-regulation
Atypical_PIKK_ATR_ATR_ST	Q03164	KMT2A	Q13535	ATR	T314	S308L	308	Missense	distal	-6	no	10.640	10.749	EPSD	TCGA;ICGC;COSMIC	10.658	Gain
Atypical_PIKK_ATR_ATR_ST	Q03164	KMT2A	Q13535	ATR	T314	G317C	317	Missense	distal	3	no	10.640	10.831	EPSD	TCGA;ICGC;COSMIC	10.658	Gain
Atypical_PIKK_ATR_ATR_ST	Q03164	KMT2A	Q13535	ATR	S419	R420Q	420	Missense	proximal	1	no	8.077	15.073	EPSD	TCGA;ICGC;COSMIC	10.658	Gain
Atypical_PIKK_ATR_ATR_ST	Q03164	KMT2A	Q13535	ATR	S470	Q467E	467	Missense	distal	-3	no	14.231	14.078	EPSD	TCGA;ICGC;COSMIC	10.658	Down-regulation
Atypical_PIKK_ATR_ATR_ST	Q03164	KMT2A	Q13535	ATR	S481	S481N	481	Missense	central	0	yes	12.718	0.000	EPSD	TCGA;ICGC;COSMIC	10.658	Loss
Atypical_PIKK_ATR_ATR_ST	Q03164	KMT2A	Q13535	ATR	T506	T506A	506	Missense	central	0	yes	11.364	0.000	EPSD	TCGA	10.658	Loss
Atypical_PIKK_ATR_ATR_ST	Q03164	KMT2A	Q13535	ATR	T506	P512S	512	Missense	distal	6	no	11.364	11.661	EPSD	TCGA;ICGC;COSMIC	10.658	Up-regulation
Atypical_PIKK_ATR_ATR_ST	Q03164	KMT2A	Q13535	ATR	T506	P512L	512	Missense	distal	6	no	11.364	11.437	EPSD	TCGA;ICGC;COSMIC	10.658	Up-regulation
Atypical_PIKK_ATR_ATR_ST	Q03164	KMT2A	Q13535	ATR	T506	R503W	503	Missense	distal	-3	no	11.364	11.728	EPSD	TCGA;ICGC;COSMIC	10.658	Up-regulation
Atypical_PIKK_ATR_ATR_ST	Q03164	KMT2A	Q13535	ATR	T506	R503Q	503	Missense	distal	-3	no	11.364	11.180	EPSD	TCGA;ICGC;COSMIC	10.658	Down-regulation
Atypical_PIKK_ATR_ATR_ST	Q03164	KMT2A	Q13535	ATR	S516	P512S	512	Missense	distal	-4	no	16.341	16.016	PhosphoSitePlus	TCGA;ICGC;COSMIC	10.658	Down-regulation
Atypical_PIKK_ATR_ATR_ST	Q03164	KMT2A	Q13535	ATR	S516	P512L	512	Missense	distal	-4	no	16.341	15.141	PhosphoSitePlus	TCGA;ICGC;COSMIC	10.658	Down-regulation
Atypical_PIKK_ATR_ATR_ST	Q03164	KMT2A	Q13535	ATR	S627	S633F	633	Missense	distal	6	no	11.319	11.161	EPSD	TCGA;ICGC;COSMIC	10.658	Down-regulation
Atypical_PIKK_ATR_ATR_ST	Q03164	KMT2A	Q13535	ATR	S627	K623N	623	Missense	distal	-4	no	11.319	10.938	EPSD	TCGA;ICGC	10.658	Down-regulation
Atypical_PIKK_ATR_ATR_ST	Q03164	KMT2A	Q13535	ATR	S680	S675L	675	Missense	distal	-5	no	10.623	10.805	EPSD	TCGA;ICGC;COSMIC	10.658	Gain
Atypical_PIKK_ATR_ATR_ST	Q03164	KMT2A	Q13535	ATR	T703	T703I	703	Missense	central	0	yes	10.803	0.000	EPSD	TCGA;ICGC;COSMIC	10.658	Loss
Atypical_PIKK_ATR_ATR_ST	Q03164	KMT2A	Q13535	ATR	T703	A699V	699	Missense	distal	-4	no	10.803	9.815	EPSD	TCGA;ICGC	10.658	Loss
Atypical_PIKK_ATR_ATR_ST	Q03164	KMT2A	Q13535	ATR	S843	T845I	845	Missense	proximal	2	no	15.502	15.220	EPSD	TCGA;ICGC;COSMIC	10.658	Down-regulation
Atypical_PIKK_ATR_ATR_ST	Q03164	KMT2A	Q13535	ATR	S843	P837S	837	Missense	distal	-6	no	15.502	15.457	EPSD	TCGA;ICGC;COSMIC	10.658	Down-regulation
Atypical_PIKK_ATR_ATR_ST	Q03164	KMT2A	Q13535	ATR	S1059	E1060D	1060	Missense	proximal	1	no	10.822	11.328	EPSD	TCGA;COSMIC	10.658	Up-regulation
Atypical_PIKK_ATR_ATR_ST	Q03164	KMT2A	Q13535	ATR	S1059	S1058L	1058	Missense	proximal	-1	no	10.822	11.058	EPSD	TCGA;ICGC;COSMIC	10.658	Up-regulation
Atypical_PIKK_ATR_ATR_ST	Q03164	KMT2A	Q13535	ATR	S1059	S1062P	1062	Missense	distal	3	no	10.822	10.758	EPSD	TCGA;ICGC;COSMIC	10.658	Down-regulation
Atypical_PIKK_ATR_ATR_ST	Q03164	KMT2A	Q13535	ATR	S1107	S1114L	1114	Missense	distal	7	no	14.530	14.692	EPSD	TCGA;ICGC;COSMIC	10.658	Up-regulation
Atypical_PIKK_ATR_ATR_ST	Q03164	KMT2A	Q13535	ATR	S1299	P1306T	1306	Missense	distal	7	no	15.557	15.565	EPSD	TCGA;ICGC	10.658	Up-regulation
Atypical_PIKK_ATR_ATR_ST	Q03164	KMT2A	Q13535	ATR	T1382	S1389Y	1389	Missense	distal	7	no	11.561	11.746	EPSD	TCGA;ICGC	10.658	Up-regulation
Atypical_PIKK_ATR_ATR_ST	Q03164	KMT2A	Q13535	ATR	S2110	T2103I	2103	Missense	distal	-7	no	14.849	14.790	EPSD	TCGA;COSMIC	10.658	Down-regulation
Atypical_PIKK_ATR_ATR_ST	Q03164	KMT2A	Q13535	ATR	S2493	P2498S	2498	Missense	distal	5	no	12.863	12.851	EPSD	TCGA	10.658	Down-regulation
Atypical_PIKK_ATR_ATR_ST	Q03164	KMT2A	Q13535	ATR	S3515	S3518A	3518	Missense	distal	3	no	11.331	10.670	EPSD	TCGA	10.658	Down-regulation
Atypical_PIKK_ATR_ATR_ST	Q03164	KMT2A	Q13535	ATR	S3515	S3518F	3518	Missense	distal	3	no	11.331	10.300	EPSD	TCGA;COSMIC	10.658	Loss
Atypical_PIKK_ATR_ATR_ST	Q03164	KMT2A	Q13535	ATR	S3576	S3579F	3579	Missense	distal	3	no	10.872	9.841	EPSD	TCGA;COSMIC	10.658	Loss
Atypical_PIKK_ATR_ATR_ST	Q02952	AKAP12	Q13535	ATR	S96	Q97L	97	Missense	proximal	1	no	14.602	9.169	EPSD	TCGA;ICGC;COSMIC	10.658	Loss
Atypical_PIKK_ATR_ATR_ST	Q02952	AKAP12	Q13535	ATR	S96	E99G	99	Missense	distal	3	no	14.602	14.423	EPSD	TCGA;ICGC;COSMIC	10.658	Down-regulation
Atypical_PIKK_ATR_ATR_ST	Q02952	AKAP12	Q13535	ATR	S151	E147K	147	Missense	distal	-4	no	12.423	12.012	EPSD	TCGA;COSMIC;CCLE	10.658	Down-regulation
Atypical_PIKK_ATR_ATR_ST	Q02952	AKAP12	Q13535	ATR	T289	V288M	288	Missense	proximal	-1	no	11.455	11.605	EPSD	TCGA;COSMIC	10.658	Up-regulation
Atypical_PIKK_ATR_ATR_ST	Q02952	AKAP12	Q13535	ATR	T289	P284T	284	Missense	distal	-5	no	11.455	11.438	EPSD	TCGA;COSMIC	10.658	Down-regulation
Atypical_PIKK_ATR_ATR_ST	Q02952	AKAP12	Q13535	ATR	S388	S392Y	392	Missense	distal	4	no	13.618	14.072	EPSD	TCGA;COSMIC	10.658	Up-regulation
Atypical_PIKK_ATR_ATR_ST	Q02952	AKAP12	Q13535	ATR	S505	R508S	508	Missense	distal	3	no	15.459	15.895	EPSD	TCGA	10.658	Up-regulation
Atypical_PIKK_ATR_ATR_ST	Q02952	AKAP12	Q13535	ATR	T521	K526Q	526	Missense	distal	5	no	11.065	11.063	EPSD	TCGA	10.658	Down-regulation
Atypical_PIKK_ATR_ATR_ST	Q02952	AKAP12	Q13535	ATR	T548	P555S	555	Missense	distal	7	no	12.896	12.732	EPSD	TCGA;COSMIC	10.658	Down-regulation
Atypical_PIKK_ATR_ATR_ST	Q02952	AKAP12	Q13535	ATR	T548	Q549E	549	Missense	proximal	1	no	12.896	6.975	EPSD	TCGA;COSMIC	10.658	Loss
Atypical_PIKK_ATR_ATR_ST	Q02952	AKAP12	Q13535	ATR	T548	P555L	555	Missense	distal	7	no	12.896	12.894	EPSD	TCGA;COSMIC	10.658	Down-regulation
Atypical_PIKK_ATR_ATR_ST	Q02952	AKAP12	Q13535	ATR	T548	S554Y	554	Missense	distal	6	no	12.896	12.400	EPSD	TCGA	10.658	Down-regulation
Atypical_PIKK_ATR_ATR_ST	Q02952	AKAP12	Q13535	ATR	S554	P555S	555	Missense	proximal	1	no	12.675	11.565	EPSD	TCGA;COSMIC	10.658	Down-regulation
Atypical_PIKK_ATR_ATR_ST	Q02952	AKAP12	Q13535	ATR	S554	Q549E	549	Missense	distal	-5	no	12.675	12.502	EPSD	TCGA;COSMIC	10.658	Down-regulation
Atypical_PIKK_ATR_ATR_ST	Q02952	AKAP12	Q13535	ATR	S554	S557N	557	Missense	distal	3	no	12.675	12.420	EPSD	TCGA;COSMIC	10.658	Down-regulation
Atypical_PIKK_ATR_ATR_ST	Q02952	AKAP12	Q13535	ATR	S554	P555L	555	Missense	proximal	1	no	12.675	12.109	EPSD	TCGA;COSMIC	10.658	Down-regulation
Atypical_PIKK_ATR_ATR_ST	Q02952	AKAP12	Q13535	ATR	S554	S554Y	554	Missense	central	0	yes	12.675	0.000	EPSD	TCGA	10.658	Loss
Atypical_PIKK_ATR_ATR_ST	Q02952	AKAP12	Q13535	ATR	S557	P555S	555	Missense	proximal	-2	no	14.036	13.985	EPSD	TCGA;COSMIC	10.658	Down-regulation
Atypical_PIKK_ATR_ATR_ST	Q02952	AKAP12	Q13535	ATR	S557	S557N	557	Missense	central	0	yes	14.036	0.000	EPSD	TCGA;COSMIC	10.658	Loss
Atypical_PIKK_ATR_ATR_ST	Q02952	AKAP12	Q13535	ATR	S557	P555L	555	Missense	proximal	-2	no	14.036	14.687	EPSD	TCGA;COSMIC	10.658	Up-regulation
Atypical_PIKK_ATR_ATR_ST	Q02952	AKAP12	Q13535	ATR	S557	S554Y	554	Missense	distal	-3	no	14.036	14.872	EPSD	TCGA	10.658	Up-regulation
Atypical_PIKK_ATR_ATR_ST	Q02952	AKAP12	Q13535	ATR	S568	S569P	569	Missense	proximal	1	no	9.680	10.789	EPSD	TCGA;COSMIC	10.658	Gain
Atypical_PIKK_ATR_ATR_ST	Q02952	AKAP12	Q13535	ATR	S598	D599N	599	Missense	proximal	1	no	10.227	11.365	EPSD	TCGA;COSMIC	10.658	Gain
Atypical_PIKK_ATR_ATR_ST	Q02952	AKAP12	Q13535	ATR	T618	R622C	622	Missense	distal	4	no	10.237	10.873	EPSD	TCGA;COSMIC	10.658	Gain
Atypical_PIKK_ATR_ATR_ST	Q02952	AKAP12	Q13535	ATR	T642	V638D	638	Missense	distal	-4	no	10.138	11.438	EPSD	TCGA;COSMIC	10.658	Gain
Atypical_PIKK_ATR_ATR_ST	Q02952	AKAP12	Q13535	ATR	S698	G703E	703	Missense	distal	5	no	10.781	10.770	EPSD	TCGA;COSMIC	10.658	Down-regulation
Atypical_PIKK_ATR_ATR_ST	Q02952	AKAP12	Q13535	ATR	S698	R691I	691	Missense	distal	-7	no	10.781	10.711	EPSD	TCGA;COSMIC	10.658	Down-regulation
Atypical_PIKK_ATR_ATR_ST	Q02952	AKAP12	Q13535	ATR	S698	G695W	695	Missense	distal	-3	no	10.781	11.641	EPSD	TCGA;COSMIC;GDSC;CCLE	10.658	Up-regulation
Atypical_PIKK_ATR_ATR_ST	Q02952	AKAP12	Q13535	ATR	S732	P737T	737	Missense	distal	5	no	17.200	17.197	PhosphoSitePlus	TCGA;COSMIC;CCLE	10.658	Down-regulation
Atypical_PIKK_ATR_ATR_ST	Q02952	AKAP12	Q13535	ATR	S732	G731S	731	Missense	proximal	-1	no	17.200	17.107	PhosphoSitePlus	TCGA;COSMIC	10.658	Down-regulation
Atypical_PIKK_ATR_ATR_ST	Q02952	AKAP12	Q13535	ATR	S732	G731V	731	Missense	proximal	-1	no	17.200	17.127	PhosphoSitePlus	TCGA;COSMIC	10.658	Down-regulation
Atypical_PIKK_ATR_ATR_ST	Q02952	AKAP12	Q13535	ATR	S732	D726N	726	Missense	distal	-6	no	17.200	17.203	PhosphoSitePlus	TCGA;COSMIC	10.658	Up-regulation
Atypical_PIKK_ATR_ATR_ST	Q02952	AKAP12	Q13535	ATR	S741	P737T	737	Missense	distal	-4	no	11.220	10.809	EPSD	TCGA;COSMIC;CCLE	10.658	Down-regulation
Atypical_PIKK_ATR_ATR_ST	Q02952	AKAP12	Q13535	ATR	S887	E886K	886	Missense	proximal	-1	no	14.016	13.767	EPSD	TCGA;COSMIC	10.658	Down-regulation
Atypical_PIKK_ATR_ATR_ST	Q02952	AKAP12	Q13535	ATR	S1054	E1052Q	1052	Missense	proximal	-2	no	14.493	14.528	EPSD	TCGA;COSMIC	10.658	Up-regulation
Atypical_PIKK_ATR_ATR_ST	Q02952	AKAP12	Q13535	ATR	S1054	G1060S	1060	Missense	distal	6	no	14.493	14.735	EPSD	TCGA	10.658	Up-regulation
Atypical_PIKK_ATR_ATR_ST	Q02952	AKAP12	Q13535	ATR	T1107	F1106C	1106	Missense	proximal	-1	no	14.075	14.625	EPSD	TCGA;COSMIC	10.658	Up-regulation
Atypical_PIKK_ATR_ATR_ST	Q02952	AKAP12	Q13535	ATR	T1107	A1101S	1101	Missense	distal	-6	no	14.075	13.968	EPSD	TCGA	10.658	Down-regulation
Atypical_PIKK_ATR_ATR_ST	Q02952	AKAP12	Q13535	ATR	T1107	Q1114K	1114	Missense	distal	7	no	14.075	14.164	EPSD	TCGA;COSMIC	10.658	Up-regulation
Atypical_PIKK_ATR_ATR_ST	Q02952	AKAP12	Q13535	ATR	T1107	P1105H	1105	Missense	proximal	-2	no	14.075	13.988	EPSD	TCGA	10.658	Down-regulation
Atypical_PIKK_ATR_ATR_ST	Q02952	AKAP12	Q13535	ATR	T1107	T1103A	1103	Missense	distal	-4	no	14.075	14.683	EPSD	TCGA;COSMIC	10.658	Up-regulation
Atypical_PIKK_ATR_ATR_ST	Q02952	AKAP12	Q13535	ATR	S1149	E1142K	1142	Missense	distal	-7	no	14.427	14.410	EPSD	TCGA;COSMIC;GDSC	10.658	Down-regulation
Atypical_PIKK_ATR_ATR_ST	Q02952	AKAP12	Q13535	ATR	T1264	S1259L	1259	Missense	distal	-5	no	13.941	14.123	EPSD	TCGA;COSMIC	10.658	Up-regulation
Atypical_PIKK_ATR_ATR_ST	Q02952	AKAP12	Q13535	ATR	T1420	A1423E	1423	Missense	distal	3	no	10.791	11.137	EPSD	TCGA;COSMIC	10.658	Up-regulation
Atypical_PIKK_ATR_ATR_ST	Q02952	AKAP12	Q13535	ATR	T1420	A1423V	1423	Missense	distal	3	no	10.791	11.551	EPSD	TCGA;COSMIC	10.658	Up-regulation
Atypical_PIKK_ATR_ATR_ST	Q02952	AKAP12	Q13535	ATR	T1420	L1421I	1421	Missense	proximal	1	no	10.791	8.734	EPSD	TCGA;COSMIC	10.658	Loss
Atypical_PIKK_ATR_ATR_ST	Q02952	AKAP12	Q13535	ATR	S1498	D1499N	1499	Missense	proximal	1	no	10.079	11.217	EPSD	TCGA;COSMIC	10.658	Gain
Atypical_PIKK_ATR_ATR_ST	Q02952	AKAP12	Q13535	ATR	S1574	E1575Q	1575	Missense	proximal	1	no	10.772	16.693	EPSD	TCGA;COSMIC	10.658	Up-regulation
Atypical_PIKK_ATR_ATR_ST	Q02952	AKAP12	Q13535	ATR	S1574	E1570K	1570	Missense	distal	-4	no	10.772	10.362	EPSD	TCGA;COSMIC	10.658	Loss
Atypical_PIKK_ATR_ATR_ST	Q02952	AKAP12	Q13535	ATR	T1578	E1575Q	1575	Missense	distal	-3	no	12.209	12.362	EPSD	TCGA;COSMIC	10.658	Up-regulation
Atypical_PIKK_ATR_ATR_ST	Q02952	AKAP12	Q13535	ATR	S1587	S1587R	1587	Missense	central	0	yes	15.239	0.000	EPSD	TCGA	10.658	Loss
Atypical_PIKK_ATR_ATR_ST	Q02952	AKAP12	Q13535	ATR	S1587	D1586G	1586	Missense	proximal	-1	no	15.239	15.145	EPSD	TCGA;COSMIC	10.658	Down-regulation
Atypical_PIKK_ATR_ATR_ST	Q02952	AKAP12	Q13535	ATR	T1730	T1724S	1724	Missense	distal	-6	no	11.563	11.477	EPSD	TCGA;COSMIC	10.658	Down-regulation
Atypical_PIKK_ATR_ATR_ST	Q9Y253	POLH	Q13535	ATR	S379	R383C	383	Missense	distal	4	no	10.304	10.941	EPSD	TCGA;ICGC;COSMIC	10.658	Gain
Atypical_PIKK_ATR_ATR_ST	Q9Y253	POLH	Q13535	ATR	T408	S409Y	409	Missense	proximal	1	no	11.581	11.244	EPSD	TCGA;ICGC;COSMIC	10.658	Down-regulation
Atypical_PIKK_ATR_ATR_ST	Q9Y253	POLH	Q13535	ATR	S523	T526A	526	Missense	distal	3	no	14.796	14.484	EPSD	TCGA;ICGC;COSMIC	10.658	Down-regulation
Atypical_PIKK_ATR_ATR_ST	Q9Y253	POLH	Q13535	ATR	S551	S550Y	550	Missense	proximal	-1	no	11.330	11.661	EPSD	TCGA;ICGC	10.658	Up-regulation
Atypical_PIKK_ATR_ATR_ST	Q9Y253	POLH	Q13535	ATR	S551	P556S	556	Missense	distal	5	no	11.330	11.318	EPSD	TCGA;ICGC	10.658	Down-regulation
Atypical_PIKK_ATR_ATR_ST	Q9Y253	POLH	Q13535	ATR	S601	M595I	595	Missense	distal	-6	no	13.889	13.908	PhosphoSitePlus	TCGA;ICGC;COSMIC	10.658	Up-regulation
Atypical_PIKK_ATR_ATR_ST	Q9Y253	POLH	Q13535	ATR	S601	L597M	597	Missense	distal	-4	no	13.889	14.544	PhosphoSitePlus	TCGA;ICGC;COSMIC	10.658	Up-regulation
Atypical_PIKK_ATR_ATR_ST	Q9Y253	POLH	Q13535	ATR	T617	V616L	616	Missense	proximal	-1	no	13.983	14.198	EPSD	TCGA;ICGC;COSMIC	10.658	Up-regulation
Atypical_PIKK_ATR_ATR_ST	Q9Y253	POLH	Q13535	ATR	T617	E615A	615	Missense	proximal	-2	no	13.983	14.462	EPSD	TCGA;ICGC;COSMIC	10.658	Up-regulation
Atypical_PIKK_ATR_ATR_ST	Q9Y253	POLH	Q13535	ATR	T617	L614P	614	Missense	distal	-3	no	13.983	13.688	EPSD	TCGA;ICGC;COSMIC	10.658	Down-regulation
Atypical_PIKK_ATR_ATR_ST	Q9Y253	POLH	Q13535	ATR	T617	S612F	612	Missense	distal	-5	no	13.983	14.209	EPSD	TCGA;ICGC	10.658	Up-regulation
Atypical_PIKK_ATR_ATR_ST	Q7Z6Z7	HUWE1	Q13535	ATR	T161	R162Q	162	Missense	proximal	1	no	4.319	11.314	EPSD	TCGA;ICGC;COSMIC	10.658	Gain
Atypical_PIKK_ATR_ATR_ST	Q7Z6Z7	HUWE1	Q13535	ATR	T340	S344I	344	Missense	distal	4	no	11.337	12.020	EPSD	TCGA;ICGC;COSMIC	10.658	Up-regulation
Atypical_PIKK_ATR_ATR_ST	Q7Z6Z7	HUWE1	Q13535	ATR	S525	I528T	528	Missense	distal	3	no	11.995	11.637	EPSD	TCGA;ICGC;COSMIC	10.658	Down-regulation
Atypical_PIKK_ATR_ATR_ST	Q7Z6Z7	HUWE1	Q13535	ATR	S649	R645M	645	Missense	distal	-4	no	10.619	10.698	EPSD	TCGA;ICGC;COSMIC	10.658	Gain
Atypical_PIKK_ATR_ATR_ST	Q7Z6Z7	HUWE1	Q13535	ATR	S649	D650N	650	Missense	proximal	1	no	10.619	11.757	EPSD	TCGA;ICGC;COSMIC	10.658	Gain
Atypical_PIKK_ATR_ATR_ST	Q7Z6Z7	HUWE1	Q13535	ATR	S649	S648I	648	Missense	proximal	-1	no	10.619	10.891	EPSD	TCGA;ICGC	10.658	Gain
Atypical_PIKK_ATR_ATR_ST	Q7Z6Z7	HUWE1	Q13535	ATR	S718	P715T	715	Missense	distal	-3	no	11.153	11.155	EPSD	TCGA	10.658	Up-regulation
Atypical_PIKK_ATR_ATR_ST	Q7Z6Z7	HUWE1	Q13535	ATR	S718	R717T	717	Missense	proximal	-1	no	11.153	11.073	EPSD	TCGA;ICGC;COSMIC	10.658	Down-regulation
Atypical_PIKK_ATR_ATR_ST	Q7Z6Z7	HUWE1	Q13535	ATR	S718	E723K	723	Missense	distal	5	no	11.153	11.162	EPSD	TCGA;ICGC;COSMIC	10.658	Up-regulation
Atypical_PIKK_ATR_ATR_ST	Q7Z6Z7	HUWE1	Q13535	ATR	S726	E733K	733	Missense	distal	7	no	11.298	11.447	EPSD	TCGA;ICGC;COSMIC	10.658	Up-regulation
Atypical_PIKK_ATR_ATR_ST	Q7Z6Z7	HUWE1	Q13535	ATR	S726	E731K	731	Missense	distal	5	no	11.298	11.307	EPSD	TCGA;ICGC;COSMIC	10.658	Up-regulation
Atypical_PIKK_ATR_ATR_ST	Q7Z6Z7	HUWE1	Q13535	ATR	S726	S727C	727	Missense	proximal	1	no	11.298	4.596	EPSD	TCGA;ICGC;COSMIC	10.658	Loss
Atypical_PIKK_ATR_ATR_ST	Q7Z6Z7	HUWE1	Q13535	ATR	S726	E728G	728	Missense	proximal	2	no	11.298	11.168	EPSD	TCGA;ICGC;COSMIC	10.658	Down-regulation
Atypical_PIKK_ATR_ATR_ST	Q7Z6Z7	HUWE1	Q13535	ATR	S726	E723K	723	Missense	distal	-3	no	11.298	11.023	EPSD	TCGA;ICGC;COSMIC	10.658	Down-regulation
Atypical_PIKK_ATR_ATR_ST	Q7Z6Z7	HUWE1	Q13535	ATR	S740	E733K	733	Missense	distal	-7	no	11.206	11.189	EPSD	TCGA;ICGC;COSMIC	10.658	Down-regulation
Atypical_PIKK_ATR_ATR_ST	Q7Z6Z7	HUWE1	Q13535	ATR	S740	M738I	738	Missense	proximal	-2	no	11.206	11.334	EPSD	TCGA;ICGC	10.658	Up-regulation
Atypical_PIKK_ATR_ATR_ST	Q7Z6Z7	HUWE1	Q13535	ATR	S740	A737V	737	Missense	distal	-3	no	11.206	10.807	EPSD	TCGA;ICGC;COSMIC	10.658	Down-regulation
Atypical_PIKK_ATR_ATR_ST	Q7Z6Z7	HUWE1	Q13535	ATR	T744	M738I	738	Missense	distal	-6	no	13.605	13.624	EPSD	TCGA;ICGC	10.658	Up-regulation
Atypical_PIKK_ATR_ATR_ST	Q7Z6Z7	HUWE1	Q13535	ATR	T744	E750Q	750	Missense	distal	6	no	13.605	13.392	EPSD	TCGA;ICGC;COSMIC	10.658	Down-regulation
Atypical_PIKK_ATR_ATR_ST	Q7Z6Z7	HUWE1	Q13535	ATR	T744	A737V	737	Missense	distal	-7	no	13.605	13.584	EPSD	TCGA;ICGC;COSMIC	10.658	Down-regulation
Atypical_PIKK_ATR_ATR_ST	Q7Z6Z7	HUWE1	Q13535	ATR	T749	E750Q	750	Missense	proximal	1	no	10.252	16.172	EPSD	TCGA;ICGC;COSMIC	10.658	Gain
Atypical_PIKK_ATR_ATR_ST	Q7Z6Z7	HUWE1	Q13535	ATR	S864	P865S	865	Missense	proximal	1	no	11.829	10.720	EPSD	TCGA;ICGC;COSMIC	10.658	Down-regulation
Atypical_PIKK_ATR_ATR_ST	Q7Z6Z7	HUWE1	Q13535	ATR	S927	S921F	921	Missense	distal	-6	no	14.559	14.639	EPSD	TCGA;ICGC;COSMIC	10.658	Up-regulation
Atypical_PIKK_ATR_ATR_ST	Q7Z6Z7	HUWE1	Q13535	ATR	S927	V933I	933	Missense	distal	6	no	14.559	14.399	EPSD	TCGA;ICGC;COSMIC	10.658	Down-regulation
Atypical_PIKK_ATR_ATR_ST	Q7Z6Z7	HUWE1	Q13535	ATR	S990	G987R	987	Missense	distal	-3	no	10.548	11.044	EPSD	TCGA;ICGC;COSMIC;GDSC;CCLE	10.658	Gain
Atypical_PIKK_ATR_ATR_ST	Q7Z6Z7	HUWE1	Q13535	ATR	T1005	E1010Q	1010	Missense	distal	5	no	15.012	15.019	EPSD	TCGA;ICGC;COSMIC	10.658	Up-regulation
Atypical_PIKK_ATR_ATR_ST	Q7Z6Z7	HUWE1	Q13535	ATR	T1005	M1001V	1001	Missense	distal	-4	no	15.012	14.763	EPSD	TCGA;ICGC;COSMIC	10.658	Down-regulation
Atypical_PIKK_ATR_ATR_ST	Q7Z6Z7	HUWE1	Q13535	ATR	S1175	T1169A	1169	Missense	distal	-6	no	12.465	12.487	EPSD	TCGA;ICGC;COSMIC	10.658	Up-regulation
Atypical_PIKK_ATR_ATR_ST	Q7Z6Z7	HUWE1	Q13535	ATR	S1183	E1184Q	1184	Missense	proximal	1	no	8.014	13.935	EPSD	TCGA;ICGC;COSMIC	10.658	Gain
Atypical_PIKK_ATR_ATR_ST	Q7Z6Z7	HUWE1	Q13535	ATR	S1218	L1216I	1216	Missense	proximal	-2	no	11.806	11.601	EPSD	TCGA;ICGC;COSMIC	10.658	Down-regulation
Atypical_PIKK_ATR_ATR_ST	Q7Z6Z7	HUWE1	Q13535	ATR	S1218	T1214M	1214	Missense	distal	-4	no	11.806	11.673	EPSD	TCGA;ICGC;COSMIC	10.658	Down-regulation
Atypical_PIKK_ATR_ATR_ST	Q7Z6Z7	HUWE1	Q13535	ATR	S1736	T1729A	1729	Missense	distal	-7	no	11.131	11.154	EPSD	TCGA;ICGC	10.658	Up-regulation
Atypical_PIKK_ATR_ATR_ST	Q7Z6Z7	HUWE1	Q13535	ATR	T2003	D2002N	2002	Missense	proximal	-1	no	13.917	14.208	EPSD	TCGA;ICGC;COSMIC;GDSC;CCLE	10.658	Up-regulation
Atypical_PIKK_ATR_ATR_ST	Q7Z6Z7	HUWE1	Q13535	ATR	T2003	R1996H	1996	Missense	distal	-7	no	13.917	13.969	EPSD	TCGA;ICGC;COSMIC	10.658	Up-regulation
Atypical_PIKK_ATR_ATR_ST	Q7Z6Z7	HUWE1	Q13535	ATR	T2003	Q1997H	1997	Missense	distal	-6	no	13.917	13.931	EPSD	TCGA;ICGC;COSMIC	10.658	Up-regulation
Atypical_PIKK_ATR_ATR_ST	Q7Z6Z7	HUWE1	Q13535	ATR	T2003	R1996L	1996	Missense	distal	-7	no	13.917	13.799	EPSD	TCGA	10.658	Down-regulation
Atypical_PIKK_ATR_ATR_ST	Q7Z6Z7	HUWE1	Q13535	ATR	T2003	T2003M	2003	Missense	central	0	yes	13.917	0.000	EPSD	TCGA;COSMIC	10.658	Loss
Atypical_PIKK_ATR_ATR_ST	Q7Z6Z7	HUWE1	Q13535	ATR	S2339	E2335Q	2335	Missense	distal	-4	no	15.536	14.405	EPSD	TCGA;ICGC;COSMIC	10.658	Down-regulation
Atypical_PIKK_ATR_ATR_ST	Q7Z6Z7	HUWE1	Q13535	ATR	S2339	E2345K	2345	Missense	distal	6	no	15.536	15.336	EPSD	TCGA;ICGC;COSMIC	10.658	Down-regulation
Atypical_PIKK_ATR_ATR_ST	Q7Z6Z7	HUWE1	Q13535	ATR	S2377	S2372N	2372	Missense	distal	-5	no	14.088	14.230	EPSD	TCGA;ICGC;COSMIC	10.658	Up-regulation
Atypical_PIKK_ATR_ATR_ST	Q7Z6Z7	HUWE1	Q13535	ATR	S2391	E2385K	2385	Missense	distal	-6	no	16.807	16.760	PhosphoSitePlus	TCGA;ICGC;COSMIC	10.658	Down-regulation
Atypical_PIKK_ATR_ATR_ST	Q7Z6Z7	HUWE1	Q13535	ATR	S2391	A2386D	2386	Missense	distal	-5	no	16.807	16.879	PhosphoSitePlus	TCGA;ICGC;COSMIC	10.658	Up-regulation
Atypical_PIKK_ATR_ATR_ST	Q7Z6Z7	HUWE1	Q13535	ATR	S2391	A2386G	2386	Missense	distal	-5	no	16.807	16.727	PhosphoSitePlus	TCGA;ICGC;COSMIC	10.658	Down-regulation
Atypical_PIKK_ATR_ATR_ST	Q7Z6Z7	HUWE1	Q13535	ATR	T2540	R2545H	2545	Missense	distal	5	no	14.630	14.625	EPSD	TCGA;COSMIC	10.658	Down-regulation
Atypical_PIKK_ATR_ATR_ST	Q7Z6Z7	HUWE1	Q13535	ATR	T2540	R2545C	2545	Missense	distal	5	no	14.630	14.646	EPSD	TCGA;ICGC;COSMIC	10.658	Up-regulation
Atypical_PIKK_ATR_ATR_ST	Q7Z6Z7	HUWE1	Q13535	ATR	T2540	R2538H	2538	Missense	proximal	-2	no	14.630	14.185	EPSD	TCGA;ICGC;COSMIC	10.658	Down-regulation
Atypical_PIKK_ATR_ATR_ST	Q7Z6Z7	HUWE1	Q13535	ATR	S2546	R2545H	2545	Missense	proximal	-1	no	12.203	12.097	EPSD	TCGA;COSMIC	10.658	Down-regulation
Atypical_PIKK_ATR_ATR_ST	Q7Z6Z7	HUWE1	Q13535	ATR	S2546	R2545C	2545	Missense	proximal	-1	no	12.203	12.627	EPSD	TCGA;ICGC;COSMIC	10.658	Up-regulation
Atypical_PIKK_ATR_ATR_ST	Q7Z6Z7	HUWE1	Q13535	ATR	S2546	R2548M	2548	Missense	proximal	2	no	12.203	12.883	EPSD	TCGA;ICGC;COSMIC	10.658	Up-regulation
Atypical_PIKK_ATR_ATR_ST	Q7Z6Z7	HUWE1	Q13535	ATR	S2636	T2635S	2635	Missense	proximal	-1	no	11.823	11.777	EPSD	TCGA;ICGC;COSMIC	10.658	Down-regulation
Atypical_PIKK_ATR_ATR_ST	Q7Z6Z7	HUWE1	Q13535	ATR	S2636	Q2631R	2631	Missense	distal	-5	no	11.823	11.916	EPSD	TCGA;ICGC;COSMIC	10.658	Up-regulation
Atypical_PIKK_ATR_ATR_ST	Q7Z6Z7	HUWE1	Q13535	ATR	S2636	S2642F	2642	Missense	distal	6	no	11.823	11.665	EPSD	TCGA;ICGC	10.658	Down-regulation
Atypical_PIKK_ATR_ATR_ST	Q7Z6Z7	HUWE1	Q13535	ATR	T2640	T2635S	2635	Missense	distal	-5	no	14.433	14.421	EPSD	TCGA;ICGC;COSMIC	10.658	Down-regulation
Atypical_PIKK_ATR_ATR_ST	Q7Z6Z7	HUWE1	Q13535	ATR	T2640	A2647V	2647	Missense	distal	7	no	14.433	14.573	EPSD	TCGA;ICGC	10.658	Up-regulation
Atypical_PIKK_ATR_ATR_ST	Q7Z6Z7	HUWE1	Q13535	ATR	T2640	S2642F	2642	Missense	proximal	2	no	14.433	11.745	EPSD	TCGA;ICGC	10.658	Down-regulation
Atypical_PIKK_ATR_ATR_ST	Q7Z6Z7	HUWE1	Q13535	ATR	S2735	P2739L	2739	Missense	distal	4	no	12.265	12.416	EPSD	TCGA;ICGC;COSMIC	10.658	Up-regulation
Atypical_PIKK_ATR_ATR_ST	Q7Z6Z7	HUWE1	Q13535	ATR	S2735	L2734I	2734	Missense	proximal	-1	no	12.265	12.302	EPSD	TCGA;ICGC;COSMIC	10.658	Up-regulation
Atypical_PIKK_ATR_ATR_ST	Q7Z6Z7	HUWE1	Q13535	ATR	T2821	M2823I	2823	Missense	proximal	2	no	15.256	14.176	EPSD	TCGA;ICGC;COSMIC	10.658	Down-regulation
Atypical_PIKK_ATR_ATR_ST	Q7Z6Z7	HUWE1	Q13535	ATR	T2889	Q2882H	2882	Missense	distal	-7	no	11.412	11.433	EPSD	TCGA;ICGC;COSMIC	10.658	Up-regulation
Atypical_PIKK_ATR_ATR_ST	Q7Z6Z7	HUWE1	Q13535	ATR	S2904	Q2901K	2901	Missense	distal	-3	no	10.709	10.281	EPSD	TCGA;ICGC;COSMIC	10.658	Loss
Atypical_PIKK_ATR_ATR_ST	Q7Z6Z7	HUWE1	Q13535	ATR	S2904	R2903K	2903	Missense	proximal	-1	no	10.709	10.474	EPSD	TCGA;ICGC;COSMIC	10.658	Loss
Atypical_PIKK_ATR_ATR_ST	Q7Z6Z7	HUWE1	Q13535	ATR	S2922	S2917R	2917	Missense	distal	-5	no	10.847	11.028	EPSD	TCGA;ICGC;COSMIC	10.658	Up-regulation
Atypical_PIKK_ATR_ATR_ST	Q7Z6Z7	HUWE1	Q13535	ATR	S2922	D2916G	2916	Missense	distal	-6	no	10.847	10.813	EPSD	TCGA;ICGC	10.658	Down-regulation
Atypical_PIKK_ATR_ATR_ST	Q7Z6Z7	HUWE1	Q13535	ATR	S2922	S2927F	2927	Missense	distal	5	no	10.847	10.859	EPSD	TCGA;ICGC;COSMIC	10.658	Up-regulation
Atypical_PIKK_ATR_ATR_ST	Q7Z6Z7	HUWE1	Q13535	ATR	S2940	R2941Q	2941	Missense	proximal	1	no	11.278	18.273	EPSD	TCGA;ICGC;COSMIC	10.658	Up-regulation
Atypical_PIKK_ATR_ATR_ST	Q7Z6Z7	HUWE1	Q13535	ATR	S3018	E3020K	3020	Missense	proximal	2	no	11.641	10.692	EPSD	TCGA;ICGC;COSMIC	10.658	Down-regulation
Atypical_PIKK_ATR_ATR_ST	Q7Z6Z7	HUWE1	Q13535	ATR	S3279	K3274N	3274	Missense	distal	-5	no	10.988	11.134	EPSD	TCGA;ICGC;COSMIC	10.658	Up-regulation
Atypical_PIKK_ATR_ATR_ST	Q7Z6Z7	HUWE1	Q13535	ATR	S3279	S3277L	3277	Missense	proximal	-2	no	10.988	11.691	EPSD	TCGA;ICGC	10.658	Up-regulation
Atypical_PIKK_ATR_ATR_ST	Q7Z6Z7	HUWE1	Q13535	ATR	S3279	H3273Y	3273	Missense	distal	-6	no	10.988	11.073	EPSD	TCGA;ICGC;COSMIC	10.658	Up-regulation
Atypical_PIKK_ATR_ATR_ST	Q7Z6Z7	HUWE1	Q13535	ATR	S3377	S3379F	3379	Missense	proximal	2	no	12.196	9.508	EPSD	TCGA;ICGC	10.658	Loss
Atypical_PIKK_ATR_ATR_ST	Q7Z6Z7	HUWE1	Q13535	ATR	S3377	S3381G	3381	Missense	distal	4	no	12.196	12.965	EPSD	TCGA	10.658	Up-regulation
Atypical_PIKK_ATR_ATR_ST	Q7Z6Z7	HUWE1	Q13535	ATR	S3560	G3562W	3562	Missense	proximal	2	no	10.937	9.372	EPSD	TCGA;ICGC;COSMIC	10.658	Loss
Atypical_PIKK_ATR_ATR_ST	Q7Z6Z7	HUWE1	Q13535	ATR	S3560	G3563A	3563	Missense	distal	3	no	10.937	10.770	EPSD	TCGA;ICGC	10.658	Down-regulation
Atypical_PIKK_ATR_ATR_ST	Q7Z6Z7	HUWE1	Q13535	ATR	S3560	P3556T	3556	Missense	distal	-4	no	10.937	10.526	EPSD	TCGA;ICGC;COSMIC	10.658	Loss
Atypical_PIKK_ATR_ATR_ST	Q7Z6Z7	HUWE1	Q13535	ATR	S3695	I3692L	3692	Missense	distal	-3	no	13.817	14.364	EPSD	TCGA;ICGC;COSMIC	10.658	Up-regulation
Atypical_PIKK_ATR_ATR_ST	Q7Z6Z7	HUWE1	Q13535	ATR	S3695	Q3696H	3696	Missense	proximal	1	no	13.817	-3.701	EPSD	TCGA;ICGC;COSMIC	10.658	Loss
Atypical_PIKK_ATR_ATR_ST	Q7Z6Z7	HUWE1	Q13535	ATR	S3695	G3701C	3701	Missense	distal	6	no	13.817	13.876	EPSD	TCGA;ICGC;COSMIC	10.658	Up-regulation
Atypical_PIKK_ATR_ATR_ST	Q7Z6Z7	HUWE1	Q13535	ATR	S3797	T3793M	3793	Missense	distal	-4	no	13.897	13.764	EPSD	TCGA;ICGC;COSMIC	10.658	Down-regulation
Atypical_PIKK_ATR_ATR_ST	Q7Z6Z7	HUWE1	Q13535	ATR	S3797	A3801V	3801	Missense	distal	4	no	13.897	13.757	EPSD	TCGA;ICGC;COSMIC	10.658	Down-regulation
Atypical_PIKK_ATR_ATR_ST	Q7Z6Z7	HUWE1	Q13535	ATR	T3822	D3828Y	3828	Missense	distal	6	no	13.748	13.442	EPSD	TCGA;ICGC;COSMIC	10.658	Down-regulation
Atypical_PIKK_ATR_ATR_ST	Q7Z6Z7	HUWE1	Q13535	ATR	T3822	P3815S	3815	Missense	distal	-7	no	13.748	13.721	EPSD	TCGA;ICGC	10.658	Down-regulation
Atypical_PIKK_ATR_ATR_ST	Q7Z6Z7	HUWE1	Q13535	ATR	S3906	A3909V	3909	Missense	distal	3	no	11.695	12.455	EPSD	TCGA;ICGC;COSMIC	10.658	Up-regulation
Atypical_PIKK_ATR_ATR_ST	Q7Z6Z7	HUWE1	Q13535	ATR	S3906	R3904S	3904	Missense	proximal	-2	no	11.695	11.285	EPSD	TCGA;ICGC;COSMIC	10.658	Down-regulation
Atypical_PIKK_ATR_ATR_ST	Q7Z6Z7	HUWE1	Q13535	ATR	S3906	A3909T	3909	Missense	distal	3	no	11.695	12.006	EPSD	TCGA;ICGC;COSMIC	10.658	Up-regulation
Atypical_PIKK_ATR_ATR_ST	Q7Z6Z7	HUWE1	Q13535	ATR	S4070	R4071Q	4071	Missense	proximal	1	no	4.138	11.133	EPSD	TCGA;ICGC;COSMIC	10.658	Gain
Atypical_PIKK_ATR_ATR_ST	Q7Z6Z7	HUWE1	Q13535	ATR	T4083	P4076S	4076	Missense	distal	-7	no	11.409	11.381	EPSD	TCGA;ICGC;COSMIC	10.658	Down-regulation
Atypical_PIKK_ATR_ATR_ST	Q7Z6Z7	HUWE1	Q13535	ATR	T4083	R4082H	4082	Missense	proximal	-1	no	11.409	11.303	EPSD	TCGA;ICGC;COSMIC	10.658	Down-regulation
Atypical_PIKK_ATR_ATR_ST	Q7Z6Z7	HUWE1	Q13535	ATR	T4083	P4076H	4076	Missense	distal	-7	no	11.409	11.386	EPSD	TCGA;ICGC;COSMIC	10.658	Down-regulation
Atypical_PIKK_ATR_ATR_ST	Q7Z6Z7	HUWE1	Q13535	ATR	T4083	S4084P	4084	Missense	proximal	1	no	11.409	12.519	EPSD	TCGA;ICGC;COSMIC	10.658	Up-regulation
Atypical_PIKK_ATR_ATR_ST	Q7Z6Z7	HUWE1	Q13535	ATR	T4083	A4079T	4079	Missense	distal	-4	no	11.409	10.802	EPSD	TCGA;ICGC;COSMIC	10.658	Down-regulation
Atypical_PIKK_ATR_ATR_ST	Q7Z6Z7	HUWE1	Q13535	ATR	T4083	F4081L	4081	Missense	proximal	-2	no	11.409	11.513	EPSD	TCGA;ICGC	10.658	Up-regulation
Atypical_PIKK_ATR_ATR_ST	Q9NZN8	CNOT2	Q13535	ATR	S45	S47F	47	Missense	proximal	2	no	12.676	9.988	EPSD	TCGA;ICGC;COSMIC	10.658	Loss
Atypical_PIKK_ATR_ATR_ST	Q9NZN8	CNOT2	Q13535	ATR	S45	S47P	47	Missense	proximal	2	no	12.676	12.991	EPSD	TCGA;ICGC;COSMIC	10.658	Up-regulation
Atypical_PIKK_ATR_ATR_ST	Q9NZN8	CNOT2	Q13535	ATR	S45	S45N	45	Missense	central	0	yes	12.676	0.000	EPSD	TCGA;ICGC;COSMIC	10.658	Loss
Atypical_PIKK_ATR_ATR_ST	Q9NZN8	CNOT2	Q13535	ATR	S45	E40K	40	Missense	distal	-5	no	12.676	12.757	EPSD	TCGA;ICGC;COSMIC	10.658	Up-regulation
Atypical_PIKK_ATR_ATR_ST	Q9NZN8	CNOT2	Q13535	ATR	S69	S65L	65	Missense	distal	-4	no	11.982	11.107	EPSD	TCGA;ICGC;COSMIC	10.658	Down-regulation
Atypical_PIKK_ATR_ATR_ST	Q9NZN8	CNOT2	Q13535	ATR	S69	A73T	73	Missense	distal	4	no	11.982	11.731	EPSD	TCGA;ICGC;COSMIC	10.658	Down-regulation
Atypical_PIKK_ATR_ATR_ST	Q9NZN8	CNOT2	Q13535	ATR	S69	L68P	68	Missense	proximal	-1	no	11.982	11.961	EPSD	TCGA;ICGC;COSMIC	10.658	Down-regulation
Atypical_PIKK_ATR_ATR_ST	Q9NZN8	CNOT2	Q13535	ATR	S69	G66V	66	Missense	distal	-3	no	11.982	12.382	EPSD	TCGA;ICGC;COSMIC	10.658	Up-regulation
Atypical_PIKK_ATR_ATR_ST	Q9NZN8	CNOT2	Q13535	ATR	S101	G103D	103	Missense	proximal	2	no	18.222	16.676	PhosphoSitePlus	TCGA;ICGC;COSMIC	10.658	Down-regulation
Atypical_PIKK_ATR_ATR_ST	Q9NZN8	CNOT2	Q13535	ATR	S101	R98C	98	Missense	distal	-3	no	18.222	18.097	PhosphoSitePlus	TCGA;ICGC;COSMIC	10.658	Down-regulation
Atypical_PIKK_ATR_ATR_ST	Q9NZN8	CNOT2	Q13535	ATR	S101	S101L	101	Missense	central	0	yes	18.222	0.000	PhosphoSitePlus	TCGA;ICGC	10.658	Loss
Atypical_PIKK_ATR_ATR_ST	Q9NZN8	CNOT2	Q13535	ATR	S143	Q144R	144	Missense	proximal	1	no	12.536	5.541	EPSD	TCGA;ICGC;COSMIC	10.658	Loss
Atypical_PIKK_ATR_ATR_ST	Q9NZN8	CNOT2	Q13535	ATR	S143	H142R	142	Missense	proximal	-1	no	12.536	12.642	EPSD	TCGA;ICGC;COSMIC	10.658	Up-regulation
Atypical_PIKK_ATR_ATR_ST	Q9NZN8	CNOT2	Q13535	ATR	S143	R137G	137	Missense	distal	-6	no	12.536	12.484	EPSD	TCGA;ICGC;COSMIC	10.658	Down-regulation
Atypical_PIKK_ATR_ATR_ST	Q9NZN8	CNOT2	Q13535	ATR	S143	G148D	148	Missense	distal	5	no	12.536	12.540	EPSD	TCGA;ICGC;COSMIC	10.658	Up-regulation
Atypical_PIKK_ATR_ATR_ST	Q9NZN8	CNOT2	Q13535	ATR	S165	P171Q	171	Missense	distal	6	no	10.527	10.696	EPSD	TCGA;ICGC;COSMIC	10.658	Gain
Atypical_PIKK_ATR_ATR_ST	Q9NZN8	CNOT2	Q13535	ATR	S170	R168G	168	Missense	proximal	-2	no	11.218	11.121	EPSD	TCGA;ICGC;COSMIC	10.658	Down-regulation
Atypical_PIKK_ATR_ATR_ST	Q9NZN8	CNOT2	Q13535	ATR	S170	P171Q	171	Missense	proximal	1	no	11.218	16.085	EPSD	TCGA;ICGC;COSMIC	10.658	Up-regulation
Atypical_PIKK_ATR_ATR_ST	Q9NZN8	CNOT2	Q13535	ATR	S170	S170L	170	Missense	central	0	yes	11.218	0.000	EPSD	TCGA;ICGC	10.658	Loss
Atypical_PIKK_ATR_ATR_ST	Q9NZN8	CNOT2	Q13535	ATR	S190	G193E	193	Missense	distal	3	no	12.653	12.832	EPSD	TCGA;ICGC	10.658	Up-regulation
Atypical_PIKK_ATR_ATR_ST	Q9NZN8	CNOT2	Q13535	ATR	S305	L302F	302	Missense	distal	-3	no	10.856	11.144	EPSD	TCGA;ICGC;COSMIC	10.658	Up-regulation
Atypical_PIKK_ATR_ATR_ST	Q9NZN8	CNOT2	Q13535	ATR	S305	S310L	310	Missense	distal	5	no	10.856	10.863	EPSD	TCGA;ICGC;COSMIC	10.658	Up-regulation
Atypical_PIKK_ATR_ATR_ST	Q9NZN8	CNOT2	Q13535	ATR	S305	S300Y	300	Missense	distal	-5	no	10.856	11.183	EPSD	TCGA	10.658	Up-regulation
Atypical_PIKK_ATR_ATR_ST	Q9NZN8	CNOT2	Q13535	ATR	S391	N394K	394	Missense	distal	3	no	12.436	12.533	EPSD	TCGA;COSMIC	10.658	Up-regulation
Atypical_PIKK_ATR_ATR_ST	Q9UH99	SUN2	Q13535	ATR	S12	D17E	17	Missense	distal	5	no	14.831	14.816	PhosphoSitePlus	TCGA;ICGC;COSMIC	10.658	Down-regulation
Atypical_PIKK_ATR_ATR_ST	Q9UH99	SUN2	Q13535	ATR	S12	D16N	16	Missense	distal	4	no	14.831	15.521	PhosphoSitePlus	TCGA;ICGC;COSMIC	10.658	Up-regulation
Atypical_PIKK_ATR_ATR_ST	Q9UH99	SUN2	Q13535	ATR	S19	D17E	17	Missense	proximal	-2	no	11.333	11.237	EPSD	TCGA;ICGC;COSMIC	10.658	Down-regulation
Atypical_PIKK_ATR_ATR_ST	Q9UH99	SUN2	Q13535	ATR	S19	D16N	16	Missense	distal	-3	no	11.333	11.625	EPSD	TCGA;ICGC;COSMIC	10.658	Up-regulation
Atypical_PIKK_ATR_ATR_ST	Q9UH99	SUN2	Q13535	ATR	S19	G24E	24	Missense	distal	5	no	11.333	11.322	EPSD	TCGA	10.658	Down-regulation
Atypical_PIKK_ATR_ATR_ST	Q9UH99	SUN2	Q13535	ATR	S30	G24E	24	Missense	distal	-6	no	15.351	15.377	EPSD	TCGA	10.658	Up-regulation
Atypical_PIKK_ATR_ATR_ST	Q9UH99	SUN2	Q13535	ATR	S110	G106D	106	Missense	distal	-4	no	9.733	11.083	EPSD	TCGA;ICGC;COSMIC	10.658	Gain
Atypical_PIKK_ATR_ATR_ST	Q9BUG6	ZSCAN5A	Q13535	ATR	S296	A291V	291	Missense	distal	-5	no	11.659	11.662	EPSD	TCGA;COSMIC	10.658	Up-regulation
Atypical_PIKK_ATR_ATR_ST	Q9BUG6	ZSCAN5A	Q13535	ATR	S296	A291T	291	Missense	distal	-5	no	11.659	11.575	EPSD	TCGA;ICGC;COSMIC	10.658	Down-regulation
Atypical_PIKK_ATR_ATR_ST	Q9BUG6	ZSCAN5A	Q13535	ATR	S308	S305P	305	Missense	distal	-3	no	12.844	13.121	EPSD	TCGA;ICGC;COSMIC	10.658	Up-regulation
Atypical_PIKK_ATR_ATR_ST	Q9BUG6	ZSCAN5A	Q13535	ATR	S308	S308F	308	Missense	central	0	yes	12.844	0.000	EPSD	TCGA;ICGC;COSMIC	10.658	Loss
Atypical_PIKK_ATR_ATR_ST	Q9BUG6	ZSCAN5A	Q13535	ATR	T422	V416I	416	Missense	distal	-6	no	16.118	16.125	PhosphoSitePlus	TCGA;ICGC;COSMIC;GDSC	10.658	Up-regulation
Atypical_PIKK_ATR_ATR_ST	Q9BUG6	ZSCAN5A	Q13535	ATR	T422	S425F	425	Missense	distal	3	no	16.118	15.087	PhosphoSitePlus	TCGA;COSMIC	10.658	Down-regulation
Atypical_PIKK_ATR_ATR_ST	Q8IZL8	PELP1	Q13535	ATR	S251	E258K	258	Missense	distal	7	no	12.188	12.337	EPSD	TCGA;ICGC;COSMIC	10.658	Up-regulation
Atypical_PIKK_ATR_ATR_ST	Q8IZL8	PELP1	Q13535	ATR	S515	K512N	512	Missense	distal	-3	no	9.838	10.998	EPSD	TCGA;COSMIC	10.658	Gain
Atypical_PIKK_ATR_ATR_ST	Q8IZL8	PELP1	Q13535	ATR	S734	E728K	728	Missense	distal	-6	no	11.506	11.459	EPSD	TCGA;COSMIC	10.658	Down-regulation
Atypical_PIKK_ATR_ATR_ST	Q8IZL8	PELP1	Q13535	ATR	S734	E736K	736	Missense	proximal	2	no	11.506	10.557	EPSD	TCGA;COSMIC	10.658	Loss
Atypical_PIKK_ATR_ATR_ST	Q8IZL8	PELP1	Q13535	ATR	S991	P997S	997	Missense	distal	6	no	11.673	11.970	EPSD	TCGA;COSMIC;CCLE	10.658	Up-regulation
Atypical_PIKK_ATR_ATR_ST	Q8IZL8	PELP1	Q13535	ATR	S991	P992L	992	Missense	proximal	1	no	11.673	11.107	EPSD	TCGA;COSMIC	10.658	Down-regulation
Atypical_PIKK_ATR_ATR_ST	Q8IZL8	PELP1	Q13535	ATR	S991	E990V	990	Missense	proximal	-1	no	11.673	11.551	EPSD	TCGA;COSMIC	10.658	Down-regulation
Atypical_PIKK_ATR_ATR_ST	Q8IZL8	PELP1	Q13535	ATR	S1033	E1038D	1038	Missense	distal	5	no	16.039	16.054	PhosphoSitePlus	TCGA;COSMIC	10.658	Up-regulation
Atypical_PIKK_ATR_ATR_ST	Q8IZL8	PELP1	Q13535	ATR	S1033	L1026M	1026	Missense	distal	-7	no	16.039	16.192	PhosphoSitePlus	TCGA	10.658	Up-regulation
Atypical_PIKK_ATR_ATR_ST	Q8IZL8	PELP1	Q13535	ATR	S1073	E1070Q	1070	Missense	distal	-3	no	11.590	11.743	EPSD	TCGA;COSMIC	10.658	Up-regulation
Atypical_PIKK_ATR_ATR_ST	Q8IZL8	PELP1	Q13535	ATR	S1073	Q1077H	1077	Missense	distal	4	no	11.590	11.302	EPSD	TCGA	10.658	Down-regulation
Atypical_PIKK_ATR_ATR_ST	O94880	PHF14	Q13535	ATR	S39	D35N	35	Missense	distal	-4	no	10.900	10.290	EPSD	TCGA;ICGC;COSMIC	10.658	Loss
Atypical_PIKK_ATR_ATR_ST	O94880	PHF14	Q13535	ATR	S59	S53I	53	Missense	distal	-6	no	12.400	12.484	EPSD	TCGA;ICGC;COSMIC	10.658	Up-regulation
Atypical_PIKK_ATR_ATR_ST	O94880	PHF14	Q13535	ATR	S59	E55D	55	Missense	distal	-4	no	12.400	12.218	EPSD	TCGA;ICGC;COSMIC	10.658	Down-regulation
Atypical_PIKK_ATR_ATR_ST	O94880	PHF14	Q13535	ATR	T162	T155A	155	Missense	distal	-7	no	11.150	11.173	EPSD	TCGA;ICGC;COSMIC	10.658	Up-regulation
Atypical_PIKK_ATR_ATR_ST	O94880	PHF14	Q13535	ATR	T162	S165F	165	Missense	distal	3	no	11.150	10.119	EPSD	TCGA	10.658	Loss
Atypical_PIKK_ATR_ATR_ST	O94880	PHF14	Q13535	ATR	S163	S165F	165	Missense	proximal	2	no	11.998	9.310	EPSD	TCGA	10.658	Loss
Atypical_PIKK_ATR_ATR_ST	O94880	PHF14	Q13535	ATR	S196	M203I	203	Missense	distal	7	no	10.801	11.126	EPSD	TCGA;ICGC;COSMIC	10.658	Up-regulation
Atypical_PIKK_ATR_ATR_ST	O94880	PHF14	Q13535	ATR	S196	R189Q	189	Missense	distal	-7	no	10.801	10.832	EPSD	TCGA;ICGC;COSMIC;GDSC	10.658	Up-regulation
Atypical_PIKK_ATR_ATR_ST	O94880	PHF14	Q13535	ATR	T287	L291P	291	Missense	distal	4	no	11.825	11.675	EPSD	TCGA;ICGC;COSMIC	10.658	Down-regulation
Atypical_PIKK_ATR_ATR_ST	O94880	PHF14	Q13535	ATR	S294	L291P	291	Missense	distal	-3	no	17.072	16.777	PhosphoSitePlus	TCGA;ICGC;COSMIC	10.658	Down-regulation
Atypical_PIKK_ATR_ATR_ST	O94880	PHF14	Q13535	ATR	S294	N299I	299	Missense	distal	5	no	17.072	17.079	PhosphoSitePlus	TCGA;ICGC;COSMIC	10.658	Up-regulation
Atypical_PIKK_ATR_ATR_ST	O94880	PHF14	Q13535	ATR	S302	K307N	307	Missense	distal	5	no	11.437	11.438	EPSD	TCGA;COSMIC	10.658	Up-regulation
Atypical_PIKK_ATR_ATR_ST	O94880	PHF14	Q13535	ATR	S302	N299I	299	Missense	distal	-3	no	11.437	10.376	EPSD	TCGA;ICGC;COSMIC	10.658	Loss
Atypical_PIKK_ATR_ATR_ST	O94880	PHF14	Q13535	ATR	S308	K307N	307	Missense	proximal	-1	no	11.856	12.441	EPSD	TCGA;COSMIC	10.658	Up-regulation
Atypical_PIKK_ATR_ATR_ST	O94880	PHF14	Q13535	ATR	S308	Q314P	314	Missense	distal	6	no	11.856	11.687	EPSD	TCGA;COSMIC	10.658	Down-regulation
Atypical_PIKK_ATR_ATR_ST	O94880	PHF14	Q13535	ATR	S313	K307N	307	Missense	distal	-6	no	13.131	13.189	EPSD	TCGA;COSMIC	10.658	Up-regulation
Atypical_PIKK_ATR_ATR_ST	O94880	PHF14	Q13535	ATR	S313	Q314P	314	Missense	proximal	1	no	13.131	8.264	EPSD	TCGA;COSMIC	10.658	Loss
Atypical_PIKK_ATR_ATR_ST	O94880	PHF14	Q13535	ATR	S598	V595L	595	Missense	distal	-3	no	10.562	10.693	EPSD	TCGA	10.658	Gain
Atypical_PIKK_ATR_ATR_ST	O94880	PHF14	Q13535	ATR	S601	S598L	598	Missense	distal	-3	no	12.380	12.952	EPSD	TCGA;COSMIC	10.658	Up-regulation
Atypical_PIKK_ATR_ATR_ST	O94880	PHF14	Q13535	ATR	S601	R607S	607	Missense	distal	6	no	12.380	12.777	EPSD	TCGA;COSMIC	10.658	Up-regulation
Atypical_PIKK_ATR_ATR_ST	O94880	PHF14	Q13535	ATR	S601	P594L	594	Missense	distal	-7	no	12.380	12.188	EPSD	TCGA;COSMIC	10.658	Down-regulation
Atypical_PIKK_ATR_ATR_ST	O94880	PHF14	Q13535	ATR	S601	V595L	595	Missense	distal	-6	no	12.380	12.413	EPSD	TCGA	10.658	Up-regulation
Atypical_PIKK_ATR_ATR_ST	O94880	PHF14	Q13535	ATR	T715	E712D	712	Missense	distal	-3	no	12.952	13.545	EPSD	TCGA;COSMIC	10.658	Up-regulation
Atypical_PIKK_ATR_ATR_ST	Q8N4S0	CCDC82	Q13535	ATR	S131	L137F	137	Missense	distal	6	no	13.651	13.717	EPSD	TCGA;ICGC;COSMIC	10.658	Up-regulation
Atypical_PIKK_ATR_ATR_ST	Q8N4S0	CCDC82	Q13535	ATR	S131	L130F	130	Missense	proximal	-1	no	13.651	13.417	EPSD	TCGA;ICGC;COSMIC	10.658	Down-regulation
Atypical_PIKK_ATR_ATR_ST	Q8N4S0	CCDC82	Q13535	ATR	S154	D159Y	159	Missense	distal	5	no	16.298	16.310	PhosphoSitePlus	TCGA;ICGC;COSMIC	10.658	Up-regulation
Atypical_PIKK_ATR_ATR_ST	Q8N4S0	CCDC82	Q13535	ATR	S154	D159A	159	Missense	distal	5	no	16.298	16.300	PhosphoSitePlus	TCGA;ICGC;COSMIC	10.658	Up-regulation
Atypical_PIKK_ATR_ATR_ST	Q8N4S0	CCDC82	Q13535	ATR	S154	Q149P	149	Missense	distal	-5	no	16.298	16.239	PhosphoSitePlus	TCGA;ICGC;COSMIC	10.658	Down-regulation
Atypical_PIKK_ATR_ATR_ST	Q8N4S0	CCDC82	Q13535	ATR	S154	N158T	158	Missense	distal	4	no	16.298	15.712	PhosphoSitePlus	TCGA;ICGC;COSMIC	10.658	Down-regulation
Atypical_PIKK_ATR_ATR_ST	Q8N4S0	CCDC82	Q13535	ATR	S154	Q149R	149	Missense	distal	-5	no	16.298	16.391	PhosphoSitePlus	TCGA;ICGC	10.658	Up-regulation
Atypical_PIKK_ATR_ATR_ST	Q8N4S0	CCDC82	Q13535	ATR	S320	L324S	324	Missense	distal	4	no	13.838	13.601	EPSD	TCGA;ICGC;COSMIC	10.658	Down-regulation
Atypical_PIKK_ATR_ATR_ST	Q8N4S0	CCDC82	Q13535	ATR	S320	Q327H	327	Missense	distal	7	no	13.838	14.069	EPSD	TCGA;ICGC;COSMIC	10.658	Up-regulation
Atypical_PIKK_ATR_ATR_ST	Q8N4S0	CCDC82	Q13535	ATR	S320	K323T	323	Missense	distal	3	no	13.838	13.647	EPSD	TCGA;ICGC;COSMIC	10.658	Down-regulation
Atypical_PIKK_ATR_ATR_ST	Q14676	MDC1	Q13535	ATR	T4	E2K	2	Missense	proximal	-2	no	13.599	13.698	EPSD	TCGA;ICGC;COSMIC	10.658	Up-regulation
Atypical_PIKK_ATR_ATR_ST	Q14676	MDC1	Q13535	ATR	S20	S21R	21	Missense	proximal	1	no	10.976	9.958	EPSD	TCGA;ICGC;COSMIC	10.658	Loss
Atypical_PIKK_ATR_ATR_ST	Q14676	MDC1	Q13535	ATR	S20	E22K	22	Missense	proximal	2	no	10.976	10.027	EPSD	TCGA;ICGC	10.658	Loss
Atypical_PIKK_ATR_ATR_ST	Q14676	MDC1	Q13535	ATR	S20	E16D	16	Missense	distal	-4	no	10.976	10.794	EPSD	TCGA;ICGC	10.658	Down-regulation
Atypical_PIKK_ATR_ATR_ST	Q14676	MDC1	Q13535	ATR	S23	V28M	28	Missense	distal	5	no	11.770	11.777	EPSD	TCGA;ICGC;COSMIC	10.658	Up-regulation
Atypical_PIKK_ATR_ATR_ST	Q14676	MDC1	Q13535	ATR	S23	S21R	21	Missense	proximal	-2	no	11.770	12.179	EPSD	TCGA;ICGC;COSMIC	10.658	Up-regulation
Atypical_PIKK_ATR_ATR_ST	Q14676	MDC1	Q13535	ATR	S23	E22K	22	Missense	proximal	-1	no	11.770	11.521	EPSD	TCGA;ICGC	10.658	Down-regulation
Atypical_PIKK_ATR_ATR_ST	Q14676	MDC1	Q13535	ATR	S23	E16D	16	Missense	distal	-7	no	11.770	11.724	EPSD	TCGA;ICGC	10.658	Down-regulation
Atypical_PIKK_ATR_ATR_ST	Q14676	MDC1	Q13535	ATR	S108	R114H	114	Missense	distal	6	no	10.591	10.666	EPSD	TCGA;ICGC;COSMIC	10.658	Gain
Atypical_PIKK_ATR_ATR_ST	Q14676	MDC1	Q13535	ATR	S202	S202F	202	Missense	central	0	yes	11.539	0.000	EPSD	TCGA;ICGC;COSMIC	10.658	Loss
Atypical_PIKK_ATR_ATR_ST	Q14676	MDC1	Q13535	ATR	S202	G206D	206	Missense	distal	4	no	11.539	10.718	EPSD	TCGA;ICGC;COSMIC	10.658	Down-regulation
Atypical_PIKK_ATR_ATR_ST	Q14676	MDC1	Q13535	ATR	S292	V287A	287	Missense	distal	-5	no	14.708	14.705	EPSD	TCGA;ICGC;COSMIC	10.658	Down-regulation
Atypical_PIKK_ATR_ATR_ST	Q14676	MDC1	Q13535	ATR	T301	T301I	301	Missense	central	0	yes	13.462	0.000	EPSD	TCGA;ICGC;COSMIC	10.658	Loss
Atypical_PIKK_ATR_ATR_ST	Q14676	MDC1	Q13535	ATR	T301	D302Y	302	Missense	proximal	1	no	13.462	12.562	EPSD	TCGA;ICGC;COSMIC	10.658	Down-regulation
Atypical_PIKK_ATR_ATR_ST	Q14676	MDC1	Q13535	ATR	S329	G325C	325	Missense	distal	-4	no	11.485	10.713	EPSD	TCGA;ICGC;COSMIC	10.658	Down-regulation
Atypical_PIKK_ATR_ATR_ST	Q14676	MDC1	Q13535	ATR	S329	G325D	325	Missense	distal	-4	no	11.485	12.834	EPSD	TCGA;ICGC;COSMIC	10.658	Up-regulation
Atypical_PIKK_ATR_ATR_ST	Q14676	MDC1	Q13535	ATR	T341	P346S	346	Missense	distal	5	no	10.689	10.678	EPSD	TCGA;ICGC;COSMIC	10.658	Down-regulation
Atypical_PIKK_ATR_ATR_ST	Q14676	MDC1	Q13535	ATR	S372	D377H	377	Missense	distal	5	no	13.331	13.327	EPSD	TCGA;ICGC;COSMIC	10.658	Down-regulation
Atypical_PIKK_ATR_ATR_ST	Q14676	MDC1	Q13535	ATR	S372	A374V	374	Missense	proximal	2	no	13.331	13.821	EPSD	TCGA;ICGC	10.658	Up-regulation
Atypical_PIKK_ATR_ATR_ST	Q14676	MDC1	Q13535	ATR	S372	A367V	367	Missense	distal	-5	no	13.331	13.334	EPSD	TCGA;ICGC;COSMIC	10.658	Up-regulation
Atypical_PIKK_ATR_ATR_ST	Q14676	MDC1	Q13535	ATR	S394	K393E	393	Missense	proximal	-1	no	16.729	16.978	EPSD	TCGA	10.658	Up-regulation
Atypical_PIKK_ATR_ATR_ST	Q14676	MDC1	Q13535	ATR	S394	S397F	397	Missense	distal	3	no	16.729	15.698	EPSD	TCGA;ICGC	10.658	Down-regulation
Atypical_PIKK_ATR_ATR_ST	Q14676	MDC1	Q13535	ATR	S397	K393E	393	Missense	distal	-4	no	10.539	10.950	EPSD	TCGA	10.658	Gain
Atypical_PIKK_ATR_ATR_ST	Q14676	MDC1	Q13535	ATR	S422	A417V	417	Missense	distal	-5	no	14.280	14.283	EPSD	TCGA;ICGC;COSMIC	10.658	Up-regulation
Atypical_PIKK_ATR_ATR_ST	Q14676	MDC1	Q13535	ATR	S498	V499M	499	Missense	proximal	1	no	-4.794	10.815	EPSD	TCGA;ICGC;COSMIC	10.658	Gain
Atypical_PIKK_ATR_ATR_ST	Q14676	MDC1	Q13535	ATR	S505	V499M	499	Missense	distal	-6	no	13.182	13.169	EPSD	TCGA;ICGC;COSMIC	10.658	Down-regulation
Atypical_PIKK_ATR_ATR_ST	Q14676	MDC1	Q13535	ATR	S505	H509Y	509	Missense	distal	4	no	13.182	14.038	EPSD	TCGA;ICGC;COSMIC	10.658	Up-regulation
Atypical_PIKK_ATR_ATR_ST	Q14676	MDC1	Q13535	ATR	S513	H509Y	509	Missense	distal	-4	no	15.062	12.964	PhosphoSitePlus	TCGA;ICGC;COSMIC	10.658	Down-regulation
Atypical_PIKK_ATR_ATR_ST	Q14676	MDC1	Q13535	ATR	S598	V591L	591	Missense	distal	-7	no	15.541	15.431	EPSD	TCGA;ICGC	10.658	Down-regulation
Atypical_PIKK_ATR_ATR_ST	Q14676	MDC1	Q13535	ATR	S641	P639L	639	Missense	proximal	-2	no	10.082	10.733	EPSD	TCGA;ICGC;COSMIC	10.658	Gain
Atypical_PIKK_ATR_ATR_ST	Q14676	MDC1	Q13535	ATR	T659	A666V	666	Missense	distal	7	no	11.187	11.327	EPSD	TCGA;ICGC;COSMIC	10.658	Up-regulation
Atypical_PIKK_ATR_ATR_ST	Q14676	MDC1	Q13535	ATR	T719	A721V	721	Missense	proximal	2	no	13.525	14.014	EPSD	TCGA;ICGC;COSMIC	10.658	Up-regulation
Atypical_PIKK_ATR_ATR_ST	Q14676	MDC1	Q13535	ATR	T725	P727S	727	Missense	proximal	2	no	10.959	10.643	EPSD	TCGA;ICGC;COSMIC	10.658	Loss
Atypical_PIKK_ATR_ATR_ST	Q14676	MDC1	Q13535	ATR	T725	A721V	721	Missense	distal	-4	no	10.959	9.970	EPSD	TCGA;ICGC;COSMIC	10.658	Loss
Atypical_PIKK_ATR_ATR_ST	Q14676	MDC1	Q13535	ATR	S874	D875H	875	Missense	proximal	1	no	11.030	-1.074	EPSD	TCGA;ICGC;COSMIC	10.658	Loss
Atypical_PIKK_ATR_ATR_ST	Q14676	MDC1	Q13535	ATR	S874	E879Q	879	Missense	distal	5	no	11.030	11.037	EPSD	TCGA;ICGC;COSMIC	10.658	Up-regulation
Atypical_PIKK_ATR_ATR_ST	Q14676	MDC1	Q13535	ATR	S874	S874P	874	Missense	central	0	yes	11.030	0.000	EPSD	TCGA;ICGC	10.658	Loss
Atypical_PIKK_ATR_ATR_ST	Q14676	MDC1	Q13535	ATR	T946	E952D	952	Missense	distal	6	no	13.763	13.488	EPSD	TCGA;ICGC	10.658	Down-regulation
Atypical_PIKK_ATR_ATR_ST	Q14676	MDC1	Q13535	ATR	S955	E952D	952	Missense	distal	-3	no	16.060	16.653	EPSD	TCGA;ICGC	10.658	Up-regulation
Atypical_PIKK_ATR_ATR_ST	Q14676	MDC1	Q13535	ATR	S963	S964N	964	Missense	proximal	1	no	10.204	11.905	EPSD	TCGA;ICGC	10.658	Gain
Atypical_PIKK_ATR_ATR_ST	Q14676	MDC1	Q13535	ATR	S988	S981L	981	Missense	distal	-7	no	12.254	12.089	EPSD	TCGA;ICGC;COSMIC	10.658	Down-regulation
Atypical_PIKK_ATR_ATR_ST	Q14676	MDC1	Q13535	ATR	S988	G992V	992	Missense	distal	4	no	12.254	11.648	EPSD	TCGA;ICGC;COSMIC	10.658	Down-regulation
Atypical_PIKK_ATR_ATR_ST	Q14676	MDC1	Q13535	ATR	S988	V984I	984	Missense	distal	-4	no	12.254	11.380	EPSD	TCGA;ICGC	10.658	Down-regulation
Atypical_PIKK_ATR_ATR_ST	Q14676	MDC1	Q13535	ATR	S1055	Q1056E	1056	Missense	proximal	1	no	13.939	8.018	EPSD	TCGA;COSMIC	10.658	Loss
Atypical_PIKK_ATR_ATR_ST	Q14676	MDC1	Q13535	ATR	S1055	N1054D	1054	Missense	proximal	-1	no	13.939	13.649	EPSD	TCGA;COSMIC	10.658	Down-regulation
Atypical_PIKK_ATR_ATR_ST	Q14676	MDC1	Q13535	ATR	S1057	Q1056E	1056	Missense	proximal	-1	no	12.221	12.306	EPSD	TCGA;COSMIC	10.658	Up-regulation
Atypical_PIKK_ATR_ATR_ST	Q14676	MDC1	Q13535	ATR	S1057	N1054D	1054	Missense	distal	-3	no	12.221	11.929	EPSD	TCGA;COSMIC	10.658	Down-regulation
Atypical_PIKK_ATR_ATR_ST	Q14676	MDC1	Q13535	ATR	S1086	P1093L	1093	Missense	distal	7	no	15.640	15.638	EPSD	TCGA;COSMIC	10.658	Down-regulation
Atypical_PIKK_ATR_ATR_ST	Q14676	MDC1	Q13535	ATR	S1086	Q1087H	1087	Missense	proximal	1	no	15.640	-1.878	EPSD	TCGA;COSMIC	10.658	Loss
Atypical_PIKK_ATR_ATR_ST	Q14676	MDC1	Q13535	ATR	S1143	P1139S	1139	Missense	distal	-4	no	14.595	14.270	EPSD	TCGA;COSMIC	10.658	Down-regulation
Atypical_PIKK_ATR_ATR_ST	Q14676	MDC1	Q13535	ATR	S1143	S1143Y	1143	Missense	central	0	yes	14.595	0.000	EPSD	TCGA	10.658	Loss
Atypical_PIKK_ATR_ATR_ST	Q14676	MDC1	Q13535	ATR	S1184	G1189V	1189	Missense	distal	5	no	13.414	13.410	EPSD	TCGA;COSMIC	10.658	Down-regulation
Atypical_PIKK_ATR_ATR_ST	Q14676	MDC1	Q13535	ATR	T1187	S1194C	1194	Missense	distal	7	no	10.621	10.983	EPSD	TCGA;ICGC;COSMIC	10.658	Gain
Atypical_PIKK_ATR_ATR_ST	Q14676	MDC1	Q13535	ATR	S1194	G1189V	1189	Missense	distal	-5	no	10.954	11.036	EPSD	TCGA;COSMIC	10.658	Up-regulation
Atypical_PIKK_ATR_ATR_ST	Q14676	MDC1	Q13535	ATR	S1194	S1194C	1194	Missense	central	0	yes	10.954	0.000	EPSD	TCGA;ICGC;COSMIC	10.658	Loss
Atypical_PIKK_ATR_ATR_ST	Q14676	MDC1	Q13535	ATR	S1225	Q1226E	1226	Missense	proximal	1	no	13.057	7.136	EPSD	TCGA;COSMIC	10.658	Loss
Atypical_PIKK_ATR_ATR_ST	Q14676	MDC1	Q13535	ATR	S1225	K1232N	1232	Missense	distal	7	no	13.057	13.327	EPSD	TCGA;COSMIC	10.658	Up-regulation
Atypical_PIKK_ATR_ATR_ST	Q14676	MDC1	Q13535	ATR	S1225	G1230E	1230	Missense	distal	5	no	13.057	13.046	EPSD	TCGA	10.658	Down-regulation
Atypical_PIKK_ATR_ATR_ST	Q14676	MDC1	Q13535	ATR	S1225	R1231I	1231	Missense	distal	6	no	13.057	13.180	EPSD	TCGA;COSMIC	10.658	Up-regulation
Atypical_PIKK_ATR_ATR_ST	Q14676	MDC1	Q13535	ATR	T1228	K1232N	1232	Missense	distal	4	no	10.285	11.054	EPSD	TCGA;COSMIC	10.658	Gain
Atypical_PIKK_ATR_ATR_ST	Q14676	MDC1	Q13535	ATR	T1228	R1231I	1231	Missense	distal	3	no	10.285	10.730	EPSD	TCGA;COSMIC	10.658	Gain
Atypical_PIKK_ATR_ATR_ST	Q14676	MDC1	Q13535	ATR	S1235	K1232N	1232	Missense	distal	-3	no	10.275	11.435	EPSD	TCGA;COSMIC	10.658	Gain
Atypical_PIKK_ATR_ATR_ST	Q14676	MDC1	Q13535	ATR	S1262	E1263Q	1263	Missense	proximal	1	no	7.425	13.345	EPSD	TCGA;COSMIC	10.658	Gain
Atypical_PIKK_ATR_ATR_ST	Q14676	MDC1	Q13535	ATR	T1269	E1263Q	1263	Missense	distal	-6	no	11.956	11.974	EPSD	TCGA;COSMIC	10.658	Up-regulation
Atypical_PIKK_ATR_ATR_ST	Q14676	MDC1	Q13535	ATR	T1269	Q1267E	1267	Missense	proximal	-2	no	11.956	11.921	EPSD	TCGA;COSMIC	10.658	Down-regulation
Atypical_PIKK_ATR_ATR_ST	Q14676	MDC1	Q13535	ATR	S1307	R1308Q	1308	Missense	proximal	1	no	5.331	12.326	EPSD	TCGA;COSMIC	10.658	Gain
Atypical_PIKK_ATR_ATR_ST	Q14676	MDC1	Q13535	ATR	S1317	R1313K	1313	Missense	distal	-4	no	11.318	12.220	EPSD	TCGA;COSMIC	10.658	Up-regulation
Atypical_PIKK_ATR_ATR_ST	Q14676	MDC1	Q13535	ATR	S1317	T1321I	1321	Missense	distal	4	no	11.318	11.949	EPSD	TCGA;COSMIC	10.658	Up-regulation
Atypical_PIKK_ATR_ATR_ST	Q14676	MDC1	Q13535	ATR	T1351	S1353N	1353	Missense	proximal	2	no	10.461	10.774	EPSD	TCGA;COSMIC	10.658	Gain
Atypical_PIKK_ATR_ATR_ST	Q14676	MDC1	Q13535	ATR	S1389	R1390Q	1390	Missense	proximal	1	no	6.029	13.024	EPSD	TCGA;COSMIC;GDSC;CCLE	10.658	Gain
Atypical_PIKK_ATR_ATR_ST	Q14676	MDC1	Q13535	ATR	S1430	P1426H	1426	Missense	distal	-4	no	13.048	12.426	EPSD	TCGA;COSMIC	10.658	Down-regulation
Atypical_PIKK_ATR_ATR_ST	Q14676	MDC1	Q13535	ATR	S1430	S1430C	1430	Missense	central	0	yes	13.048	0.000	EPSD	TCGA;COSMIC	10.658	Loss
Atypical_PIKK_ATR_ATR_ST	Q14676	MDC1	Q13535	ATR	S1430	T1425A	1425	Missense	distal	-5	no	13.048	13.131	EPSD	TCGA;COSMIC	10.658	Up-regulation
Atypical_PIKK_ATR_ATR_ST	Q14676	MDC1	Q13535	ATR	S1430	G1435D	1435	Missense	distal	5	no	13.048	13.052	EPSD	TCGA;COSMIC	10.658	Up-regulation
Atypical_PIKK_ATR_ATR_ST	Q14676	MDC1	Q13535	ATR	T1433	P1426H	1426	Missense	distal	-7	no	10.879	10.856	EPSD	TCGA;COSMIC	10.658	Down-regulation
Atypical_PIKK_ATR_ATR_ST	Q14676	MDC1	Q13535	ATR	T1433	S1440F	1440	Missense	distal	7	no	10.879	10.941	EPSD	TCGA;COSMIC	10.658	Up-regulation
Atypical_PIKK_ATR_ATR_ST	Q14676	MDC1	Q13535	ATR	T1433	S1430C	1430	Missense	distal	-3	no	10.879	11.290	EPSD	TCGA;COSMIC	10.658	Up-regulation
Atypical_PIKK_ATR_ATR_ST	Q14676	MDC1	Q13535	ATR	T1433	G1435D	1435	Missense	proximal	2	no	10.879	9.333	EPSD	TCGA;COSMIC	10.658	Loss
Atypical_PIKK_ATR_ATR_ST	Q14676	MDC1	Q13535	ATR	S1440	S1440F	1440	Missense	central	0	yes	11.334	0.000	EPSD	TCGA;COSMIC	10.658	Loss
Atypical_PIKK_ATR_ATR_ST	Q14676	MDC1	Q13535	ATR	S1440	G1435D	1435	Missense	distal	-5	no	11.334	11.487	EPSD	TCGA;COSMIC	10.658	Up-regulation
Atypical_PIKK_ATR_ATR_ST	Q14676	MDC1	Q13535	ATR	S1471	P1469H	1469	Missense	proximal	-2	no	13.703	13.615	EPSD	TCGA;COSMIC	10.658	Down-regulation
Atypical_PIKK_ATR_ATR_ST	Q14676	MDC1	Q13535	ATR	T1474	P1469H	1469	Missense	distal	-5	no	10.756	10.847	EPSD	TCGA;COSMIC	10.658	Up-regulation
Atypical_PIKK_ATR_ATR_ST	Q14676	MDC1	Q13535	ATR	T1474	R1480I	1480	Missense	distal	6	no	10.756	10.879	EPSD	TCGA	10.658	Up-regulation
Atypical_PIKK_ATR_ATR_ST	Q14676	MDC1	Q13535	ATR	T1474	R1480K	1480	Missense	distal	6	no	10.756	11.038	EPSD	TCGA;COSMIC	10.658	Up-regulation
Atypical_PIKK_ATR_ATR_ST	Q14676	MDC1	Q13535	ATR	S1512	R1513Q	1513	Missense	proximal	1	no	5.590	12.585	EPSD	TCGA;COSMIC	10.658	Gain
Atypical_PIKK_ATR_ATR_ST	Q14676	MDC1	Q13535	ATR	S1522	R1518K	1518	Missense	distal	-4	no	10.588	11.490	EPSD	TCGA;COSMIC	10.658	Gain
Atypical_PIKK_ATR_ATR_ST	Q14676	MDC1	Q13535	ATR	S1604	S1605C	1605	Missense	proximal	1	no	10.741	4.039	EPSD	TCGA;COSMIC	10.658	Loss
Atypical_PIKK_ATR_ATR_ST	Q14676	MDC1	Q13535	ATR	S1604	V1606F	1606	Missense	proximal	2	no	10.741	7.416	EPSD	TCGA	10.658	Loss
Atypical_PIKK_ATR_ATR_ST	Q14676	MDC1	Q13535	ATR	S1604	R1603W	1603	Missense	proximal	-1	no	10.741	10.838	EPSD	TCGA;COSMIC	10.658	Up-regulation
Atypical_PIKK_ATR_ATR_ST	Q14676	MDC1	Q13535	ATR	S1702	E1699A	1699	Missense	distal	-3	no	12.752	13.392	EPSD	TCGA	10.658	Up-regulation
Atypical_PIKK_ATR_ATR_ST	Q14676	MDC1	Q13535	ATR	S1702	E1699Q	1699	Missense	distal	-3	no	12.752	12.905	EPSD	TCGA;COSMIC	10.658	Up-regulation
Atypical_PIKK_ATR_ATR_ST	Q14676	MDC1	Q13535	ATR	S1702	P1703S	1703	Missense	proximal	1	no	12.752	11.643	EPSD	TCGA;COSMIC	10.658	Down-regulation
Atypical_PIKK_ATR_ATR_ST	Q14676	MDC1	Q13535	ATR	S1711	I1710F	1710	Missense	proximal	-1	no	12.191	11.921	EPSD	TCGA;ICGC;COSMIC	10.658	Down-regulation
Atypical_PIKK_ATR_ATR_ST	Q14676	MDC1	Q13535	ATR	S1711	S1711F	1711	Missense	central	0	yes	12.191	0.000	EPSD	TCGA;ICGC;COSMIC	10.658	Loss
Atypical_PIKK_ATR_ATR_ST	Q14676	MDC1	Q13535	ATR	T1716	I1710F	1710	Missense	distal	-6	no	12.022	12.018	EPSD	TCGA;ICGC;COSMIC	10.658	Down-regulation
Atypical_PIKK_ATR_ATR_ST	Q14676	MDC1	Q13535	ATR	T1716	S1711F	1711	Missense	distal	-5	no	12.022	12.249	EPSD	TCGA;ICGC;COSMIC	10.658	Up-regulation
Atypical_PIKK_ATR_ATR_ST	Q14676	MDC1	Q13535	ATR	T1781	H1784Y	1784	Missense	distal	3	no	12.451	11.561	EPSD	TCGA;COSMIC	10.658	Down-regulation
Atypical_PIKK_ATR_ATR_ST	Q14676	MDC1	Q13535	ATR	T1781	L1778R	1778	Missense	distal	-3	no	12.451	12.416	EPSD	TCGA;ICGC;COSMIC	10.658	Down-regulation
Atypical_PIKK_ATR_ATR_ST	Q14676	MDC1	Q13535	ATR	S1786	H1784Y	1784	Missense	proximal	-2	no	11.649	12.524	EPSD	TCGA;COSMIC	10.658	Up-regulation
Atypical_PIKK_ATR_ATR_ST	Q14676	MDC1	Q13535	ATR	S1833	P1827S	1827	Missense	distal	-6	no	13.250	13.204	EPSD	TCGA;COSMIC	10.658	Down-regulation
Atypical_PIKK_ATR_ATR_ST	Q14676	MDC1	Q13535	ATR	T1858	V1857M	1857	Missense	proximal	-1	no	11.139	11.289	EPSD	TCGA;ICGC;COSMIC	10.658	Up-regulation
Atypical_PIKK_ATR_ATR_ST	Q14676	MDC1	Q13535	ATR	T1858	D1855Y	1855	Missense	distal	-3	no	11.139	11.182	EPSD	TCGA;ICGC;COSMIC	10.658	Up-regulation
Atypical_PIKK_ATR_ATR_ST	Q14676	MDC1	Q13535	ATR	T1858	T1858I	1858	Missense	central	0	yes	11.139	0.000	EPSD	TCGA;ICGC;COSMIC	10.658	Loss
Atypical_PIKK_ATR_ATR_ST	Q6PGQ7	BORA	Q13535	ATR	S41	E36A	36	Missense	distal	-5	no	11.228	11.408	EPSD	TCGA;ICGC	10.658	Up-regulation
Atypical_PIKK_ATR_ATR_ST	Q6PGQ7	BORA	Q13535	ATR	S41	F45L	45	Missense	distal	4	no	11.228	11.446	EPSD	TCGA	10.658	Up-regulation
Atypical_PIKK_ATR_ATR_ST	Q6PGQ7	BORA	Q13535	ATR	S233	S229L	229	Missense	distal	-4	no	12.040	11.166	EPSD	TCGA;ICGC	10.658	Down-regulation
Atypical_PIKK_ATR_ATR_ST	Q6PGQ7	BORA	Q13535	ATR	S233	D231Y	231	Missense	proximal	-2	no	12.040	12.487	EPSD	TCGA;ICGC	10.658	Up-regulation
Atypical_PIKK_ATR_ATR_ST	Q6PGQ7	BORA	Q13535	ATR	T243	S246L	246	Missense	distal	3	no	12.927	12.260	EPSD	TCGA;ICGC	10.658	Down-regulation
Atypical_PIKK_ATR_ATR_ST	Q6PGQ7	BORA	Q13535	ATR	S245	S246L	246	Missense	proximal	1	no	10.958	11.502	EPSD	TCGA;ICGC	10.658	Up-regulation
Atypical_PIKK_ATR_ATR_ST	Q6PGQ7	BORA	Q13535	ATR	S262	S257T	257	Missense	distal	-5	no	11.833	11.846	EPSD	TCGA;ICGC	10.658	Up-regulation
Atypical_PIKK_ATR_ATR_ST	Q6PGQ7	BORA	Q13535	ATR	S278	I284T	284	Missense	distal	6	no	12.398	12.624	EPSD	TCGA;ICGC	10.658	Up-regulation
Atypical_PIKK_ATR_ATR_ST	Q6PGQ7	BORA	Q13535	ATR	S278	I272V	272	Missense	distal	-6	no	12.398	12.391	EPSD	TCGA;ICGC	10.658	Down-regulation
Atypical_PIKK_ATR_ATR_ST	Q6PGQ7	BORA	Q13535	ATR	S278	I280T	280	Missense	proximal	2	no	12.398	12.680	EPSD	TCGA;ICGC	10.658	Up-regulation
Atypical_PIKK_ATR_ATR_ST	Q6PGQ7	BORA	Q13535	ATR	S303	S308F	308	Missense	distal	5	no	10.895	10.907	EPSD	TCGA;ICGC	10.658	Up-regulation
Atypical_PIKK_ATR_ATR_ST	Q6PGQ7	BORA	Q13535	ATR	T306	S308F	308	Missense	proximal	2	no	10.877	8.189	EPSD	TCGA;ICGC	10.658	Loss
Atypical_PIKK_ATR_ATR_ST	Q6PGQ7	BORA	Q13535	ATR	S308	S308F	308	Missense	central	0	yes	11.814	0.000	EPSD	TCGA;ICGC	10.658	Loss
Atypical_PIKK_ATR_ATR_ST	O43542	XRCC3	Q13535	ATR	S225	R220C	220	Missense	distal	-5	no	16.260	16.267	PhosphoSitePlus	TCGA;ICGC;COSMIC	10.658	Up-regulation
Atypical_PIKK_ATR_ATR_ST	O43542	XRCC3	Q13535	ATR	S225	R220H	220	Missense	distal	-5	no	16.260	16.199	PhosphoSitePlus	TCGA;ICGC;COSMIC	10.658	Down-regulation
Atypical_PIKK_ATR_ATR_ST	O43542	XRCC3	Q13535	ATR	S225	A229T	229	Missense	distal	4	no	16.260	16.009	PhosphoSitePlus	TCGA;ICGC;COSMIC;GDSC;CCLE	10.658	Down-regulation
Atypical_PIKK_ATR_ATR_ST	O43542	XRCC3	Q13535	ATR	S225	E222Q	222	Missense	distal	-3	no	16.260	16.413	PhosphoSitePlus	TCGA;ICGC;COSMIC	10.658	Up-regulation
Atypical_PIKK_ATR_ATR_ST	O00213	APBB1	Q13535	ATR	S175	E181D	181	Missense	distal	6	no	11.825	11.550	EPSD	TCGA;ICGC;COSMIC	10.658	Down-regulation
Atypical_PIKK_ATR_ATR_ST	O00213	APBB1	Q13535	ATR	S228	S233C	233	Missense	distal	5	no	16.139	16.165	PhosphoSitePlus	TCGA;ICGC;COSMIC	10.658	Up-regulation
Atypical_PIKK_ATR_ATR_ST	O00213	APBB1	Q13535	ATR	S228	W224G	224	Missense	distal	-4	no	16.139	15.462	PhosphoSitePlus	TCGA;ICGC;COSMIC	10.658	Down-regulation
Atypical_PIKK_ATR_ATR_ST	O00213	APBB1	Q13535	ATR	S228	S228F	228	Missense	central	0	yes	16.139	0.000	PhosphoSitePlus	TCGA;ICGC;COSMIC	10.658	Loss
Atypical_PIKK_ATR_ATR_ST	O00213	APBB1	Q13535	ATR	S287	P288L	288	Missense	proximal	1	no	11.262	10.696	EPSD	TCGA;COSMIC	10.658	Down-regulation
Atypical_PIKK_ATR_ATR_ST	O00213	APBB1	Q13535	ATR	S287	G284V	284	Missense	distal	-3	no	11.262	11.661	EPSD	TCGA	10.658	Up-regulation
Atypical_PIKK_ATR_ATR_ST	O00213	APBB1	Q13535	ATR	S287	R285W	285	Missense	proximal	-2	no	11.262	11.368	EPSD	TCGA;COSMIC	10.658	Up-regulation
Atypical_PIKK_ATR_ATR_ST	O00213	APBB1	Q13535	ATR	S287	P288S	288	Missense	proximal	1	no	11.262	10.152	EPSD	TCGA;COSMIC	10.658	Loss
Atypical_PIKK_ATR_ATR_ST	O00213	APBB1	Q13535	ATR	S287	G284S	284	Missense	distal	-3	no	11.262	11.221	EPSD	TCGA;COSMIC	10.658	Down-regulation
Atypical_PIKK_ATR_ATR_ST	O00213	APBB1	Q13535	ATR	S289	P288L	288	Missense	proximal	-1	no	16.933	16.954	EPSD	TCGA;COSMIC	10.658	Up-regulation
Atypical_PIKK_ATR_ATR_ST	O00213	APBB1	Q13535	ATR	S289	G284V	284	Missense	distal	-5	no	16.933	17.016	EPSD	TCGA	10.658	Up-regulation
Atypical_PIKK_ATR_ATR_ST	O00213	APBB1	Q13535	ATR	S289	R285W	285	Missense	distal	-4	no	16.933	17.391	EPSD	TCGA;COSMIC	10.658	Up-regulation
Atypical_PIKK_ATR_ATR_ST	O00213	APBB1	Q13535	ATR	S289	P288S	288	Missense	proximal	-1	no	16.933	16.718	EPSD	TCGA;COSMIC	10.658	Down-regulation
Atypical_PIKK_ATR_ATR_ST	O00213	APBB1	Q13535	ATR	S289	G284S	284	Missense	distal	-5	no	16.933	16.918	EPSD	TCGA;COSMIC	10.658	Down-regulation
Atypical_PIKK_ATR_ATR_ST	O00213	APBB1	Q13535	ATR	S322	W317R	317	Missense	distal	-5	no	13.484	13.454	EPSD	TCGA;COSMIC	10.658	Down-regulation
Atypical_PIKK_ATR_ATR_ST	O00213	APBB1	Q13535	ATR	S322	K318N	318	Missense	distal	-4	no	13.484	13.104	EPSD	TCGA	10.658	Down-regulation
Atypical_PIKK_ATR_ATR_ST	O00213	APBB1	Q13535	ATR	S347	Q353H	353	Missense	distal	6	no	12.192	11.999	EPSD	TCGA;COSMIC	10.658	Down-regulation
Atypical_PIKK_ATR_ATR_ST	O00213	APBB1	Q13535	ATR	S347	Q344H	344	Missense	distal	-3	no	12.192	12.008	EPSD	TCGA;COSMIC	10.658	Down-regulation
Atypical_PIKK_ATR_ATR_ST	O00213	APBB1	Q13535	ATR	S347	P350L	350	Missense	distal	3	no	12.192	11.589	EPSD	TCGA;COSMIC	10.658	Down-regulation
Atypical_PIKK_ATR_ATR_ST	O00213	APBB1	Q13535	ATR	S347	A343T	343	Missense	distal	-4	no	12.192	11.585	EPSD	TCGA;COSMIC	10.658	Down-regulation
Atypical_PIKK_ATR_ATR_ST	P55072	VCP	Q13535	ATR	S78	M84I	84	Missense	distal	6	no	12.232	12.299	EPSD	TCGA	10.658	Up-regulation
Atypical_PIKK_ATR_ATR_ST	P55072	VCP	Q13535	ATR	S78	R83Q	83	Missense	distal	5	no	12.232	12.223	EPSD	TCGA;ICGC;COSMIC	10.658	Down-regulation
Atypical_PIKK_ATR_ATR_ST	P55072	VCP	Q13535	ATR	S326	S326L	326	Missense	central	0	yes	15.043	0.000	EPSD	TCGA;ICGC;COSMIC	10.658	Loss
Atypical_PIKK_ATR_ATR_ST	P55072	VCP	Q13535	ATR	S326	R323H	323	Missense	distal	-3	no	15.043	14.675	EPSD	TCGA;ICGC;COSMIC;GDSC;CCLE	10.658	Down-regulation
Atypical_PIKK_ATR_ATR_ST	P55072	VCP	Q13535	ATR	T347	S352N	352	Missense	distal	5	no	12.211	12.216	EPSD	TCGA;ICGC	10.658	Up-regulation
Atypical_PIKK_ATR_ATR_ST	P55072	VCP	Q13535	ATR	T347	S352I	352	Missense	distal	5	no	12.211	12.223	EPSD	TCGA;ICGC	10.658	Up-regulation
Atypical_PIKK_ATR_ATR_ST	P55072	VCP	Q13535	ATR	S457	R453Q	453	Missense	distal	-4	no	15.584	15.766	EPSD	TCGA;ICGC;COSMIC	10.658	Up-regulation
Atypical_PIKK_ATR_ATR_ST	P55072	VCP	Q13535	ATR	S652	R653L	653	Missense	proximal	1	no	9.273	10.834	EPSD	TCGA;ICGC;COSMIC	10.658	Gain
Atypical_PIKK_ATR_ATR_ST	P55072	VCP	Q13535	ATR	S765	R772G	772	Missense	distal	7	no	10.946	10.689	EPSD	TCGA;ICGC;COSMIC	10.658	Down-regulation
Atypical_PIKK_ATR_ATR_ST	Q8TAQ2	SMARCC2	Q13535	ATR	S69	P72L	72	Missense	distal	3	no	11.623	11.020	EPSD	TCGA;ICGC;COSMIC	10.658	Down-regulation
Atypical_PIKK_ATR_ATR_ST	Q8TAQ2	SMARCC2	Q13535	ATR	S302	S304C	304	Missense	proximal	2	no	11.057	9.373	EPSD	TCGA;ICGC;COSMIC	10.658	Loss
Atypical_PIKK_ATR_ATR_ST	Q8TAQ2	SMARCC2	Q13535	ATR	S302	S306L	306	Missense	distal	4	no	11.057	11.294	EPSD	TCGA;ICGC;COSMIC	10.658	Up-regulation
Atypical_PIKK_ATR_ATR_ST	Q8TAQ2	SMARCC2	Q13535	ATR	S302	P305A	305	Missense	distal	3	no	11.057	10.460	EPSD	TCGA;ICGC;COSMIC	10.658	Loss
Atypical_PIKK_ATR_ATR_ST	Q8TAQ2	SMARCC2	Q13535	ATR	S302	R301C	301	Missense	proximal	-1	no	11.057	11.481	EPSD	TCGA;ICGC	10.658	Up-regulation
Atypical_PIKK_ATR_ATR_ST	Q8TAQ2	SMARCC2	Q13535	ATR	T308	S306L	306	Missense	proximal	-2	no	10.455	11.158	EPSD	TCGA;ICGC;COSMIC	10.658	Gain
Atypical_PIKK_ATR_ATR_ST	Q8TAQ2	SMARCC2	Q13535	ATR	T308	P305A	305	Missense	distal	-3	no	10.455	11.018	EPSD	TCGA;ICGC;COSMIC	10.658	Gain
Atypical_PIKK_ATR_ATR_ST	Q8TAQ2	SMARCC2	Q13535	ATR	S347	E354Q	354	Missense	distal	7	no	12.264	12.324	EPSD	TCGA;ICGC;COSMIC	10.658	Up-regulation
Atypical_PIKK_ATR_ATR_ST	Q8TAQ2	SMARCC2	Q13535	ATR	S347	P350L	350	Missense	distal	3	no	12.264	11.661	EPSD	TCGA;ICGC;COSMIC	10.658	Down-regulation
Atypical_PIKK_ATR_ATR_ST	Q8TAQ2	SMARCC2	Q13535	ATR	S347	N351S	351	Missense	distal	4	no	12.264	11.627	EPSD	TCGA;ICGC;COSMIC	10.658	Down-regulation
Atypical_PIKK_ATR_ATR_ST	Q8TAQ2	SMARCC2	Q13535	ATR	S347	V352I	352	Missense	distal	5	no	12.264	12.275	EPSD	TCGA;ICGC;COSMIC;CCLE	10.658	Up-regulation
Atypical_PIKK_ATR_ATR_ST	Q8TAQ2	SMARCC2	Q13535	ATR	S387	E386K	386	Missense	proximal	-1	no	12.345	12.096	EPSD	TCGA;ICGC;COSMIC	10.658	Down-regulation
Atypical_PIKK_ATR_ATR_ST	Q8TAQ2	SMARCC2	Q13535	ATR	S387	T390M	390	Missense	distal	3	no	12.345	12.003	EPSD	TCGA;ICGC;COSMIC	10.658	Down-regulation
Atypical_PIKK_ATR_ATR_ST	Q8TAQ2	SMARCC2	Q13535	ATR	S387	D385N	385	Missense	proximal	-2	no	12.345	12.802	EPSD	TCGA;ICGC;COSMIC	10.658	Up-regulation
Atypical_PIKK_ATR_ATR_ST	Q8TAQ2	SMARCC2	Q13535	ATR	S399	T400M	400	Missense	proximal	1	no	6.972	12.405	EPSD	TCGA;ICGC;COSMIC	10.658	Gain
Atypical_PIKK_ATR_ATR_ST	Q8TAQ2	SMARCC2	Q13535	ATR	T400	E395Q	395	Missense	distal	-5	no	10.814	10.987	EPSD	TCGA;ICGC;COSMIC	10.658	Up-regulation
Atypical_PIKK_ATR_ATR_ST	Q8TAQ2	SMARCC2	Q13535	ATR	T400	T400M	400	Missense	central	0	yes	10.814	0.000	EPSD	TCGA;ICGC;COSMIC	10.658	Loss
Atypical_PIKK_ATR_ATR_ST	Q8TAQ2	SMARCC2	Q13535	ATR	S555	S553F	553	Missense	proximal	-2	no	15.275	15.874	EPSD	TCGA;ICGC;COSMIC	10.658	Up-regulation
Atypical_PIKK_ATR_ATR_ST	Q8TAQ2	SMARCC2	Q13535	ATR	S555	T552I	552	Missense	distal	-3	no	15.275	15.021	EPSD	TCGA;ICGC;COSMIC	10.658	Down-regulation
Atypical_PIKK_ATR_ATR_ST	Q8TAQ2	SMARCC2	Q13535	ATR	S841	K848N	848	Missense	distal	7	no	10.754	11.025	EPSD	TCGA;ICGC	10.658	Up-regulation
Atypical_PIKK_ATR_ATR_ST	Q8TAQ2	SMARCC2	Q13535	ATR	S841	K836N	836	Missense	distal	-5	no	10.754	10.899	EPSD	TCGA;ICGC;COSMIC	10.658	Up-regulation
Atypical_PIKK_ATR_ATR_ST	Q8TAQ2	SMARCC2	Q13535	ATR	S841	E844G	844	Missense	distal	3	no	10.754	10.575	EPSD	TCGA;ICGC;COSMIC	10.658	Loss
Atypical_PIKK_ATR_ATR_ST	Q8TAQ2	SMARCC2	Q13535	ATR	S969	T975I	975	Missense	distal	6	no	16.789	16.563	PhosphoSitePlus	TCGA;ICGC;COSMIC	10.658	Down-regulation
Atypical_PIKK_ATR_ATR_ST	Q8TAQ2	SMARCC2	Q13535	ATR	S969	P974S	974	Missense	distal	5	no	16.789	16.778	PhosphoSitePlus	TCGA;ICGC;COSMIC	10.658	Down-regulation
Atypical_PIKK_ATR_ATR_ST	Q8N163	CCAR2	Q13535	ATR	S302	A305T	305	Missense	distal	3	no	10.933	11.244	EPSD	TCGA;ICGC;COSMIC	10.658	Up-regulation
Atypical_PIKK_ATR_ATR_ST	Q8N163	CCAR2	Q13535	ATR	S302	K309N	309	Missense	distal	7	no	10.933	11.203	EPSD	TCGA;GDSC	10.658	Up-regulation
Atypical_PIKK_ATR_ATR_ST	Q8N163	CCAR2	Q13535	ATR	S302	S308L	308	Missense	distal	6	no	10.933	10.708	EPSD	TCGA	10.658	Down-regulation
Atypical_PIKK_ATR_ATR_ST	Q8N163	CCAR2	Q13535	ATR	T489	T484I	484	Missense	distal	-5	no	12.293	12.484	EPSD	TCGA;COSMIC	10.658	Up-regulation
Atypical_PIKK_ATR_ATR_ST	Q8N163	CCAR2	Q13535	ATR	T489	A482T	482	Missense	distal	-7	no	12.293	12.270	EPSD	TCGA;COSMIC	10.658	Down-regulation
Atypical_PIKK_ATR_ATR_ST	O75717	WDHD1	Q13535	ATR	S127	R133Q	133	Missense	distal	6	no	12.344	12.612	EPSD	TCGA;COSMIC	10.658	Up-regulation
Atypical_PIKK_ATR_ATR_ST	O75717	WDHD1	Q13535	ATR	S127	S126R	126	Missense	proximal	-1	no	12.344	12.471	EPSD	TCGA;COSMIC	10.658	Up-regulation
Atypical_PIKK_ATR_ATR_ST	O75717	WDHD1	Q13535	ATR	S127	M124I	124	Missense	distal	-3	no	12.344	12.353	EPSD	TCGA;COSMIC	10.658	Up-regulation
Atypical_PIKK_ATR_ATR_ST	O75717	WDHD1	Q13535	ATR	S416	H409D	409	Missense	distal	-7	no	16.623	16.603	EPSD	TCGA;COSMIC	10.658	Down-regulation
Atypical_PIKK_ATR_ATR_ST	O75717	WDHD1	Q13535	ATR	T826	E822K	822	Missense	distal	-4	no	13.519	13.109	PhosphoSitePlus	TCGA;COSMIC	10.658	Down-regulation
Atypical_PIKK_ATR_ATR_ST	O75717	WDHD1	Q13535	ATR	T850	E851Q	851	Missense	proximal	1	no	7.637	13.557	EPSD	TCGA;COSMIC	10.658	Gain
Atypical_PIKK_ATR_ATR_ST	O75717	WDHD1	Q13535	ATR	S853	E851Q	851	Missense	proximal	-2	no	10.850	10.885	EPSD	TCGA;COSMIC	10.658	Up-regulation
Atypical_PIKK_ATR_ATR_ST	O75717	WDHD1	Q13535	ATR	S907	V903I	903	Missense	distal	-4	no	16.617	15.743	EPSD	TCGA	10.658	Down-regulation
Atypical_PIKK_ATR_ATR_ST	O75717	WDHD1	Q13535	ATR	S926	A930T	930	Missense	distal	4	no	12.124	11.873	EPSD	TCGA	10.658	Down-regulation
Atypical_PIKK_ATR_ATR_ST	O75717	WDHD1	Q13535	ATR	S984	R982I	982	Missense	proximal	-2	no	13.455	13.543	EPSD	TCGA;COSMIC	10.658	Up-regulation
Atypical_PIKK_ATR_ATR_ST	O75717	WDHD1	Q13535	ATR	S1090	R1085C	1085	Missense	distal	-5	no	10.801	10.809	EPSD	TCGA;COSMIC	10.658	Up-regulation
Atypical_PIKK_ATR_ATR_ST	O75717	WDHD1	Q13535	ATR	S1090	R1085S	1085	Missense	distal	-5	no	10.801	10.620	EPSD	TCGA	10.658	Loss
Atypical_PIKK_ATR_ATR_ST	O75717	WDHD1	Q13535	ATR	S1090	Q1096H	1096	Missense	distal	6	no	10.801	10.608	EPSD	TCGA	10.658	Loss
Atypical_PIKK_ATR_ATR_ST	O75717	WDHD1	Q13535	ATR	S1107	K1108Q	1108	Missense	proximal	1	no	4.253	15.219	EPSD	TCGA;COSMIC	10.658	Gain
Atypical_PIKK_ATR_ATR_ST	P49006	MARCKSL1	Q13535	ATR	S22	A19T	19	Missense	distal	-3	no	12.778	12.217	EPSD	TCGA;ICGC;COSMIC	10.658	Down-regulation
Atypical_PIKK_ATR_ATR_ST	P49006	MARCKSL1	Q13535	ATR	S71	A64V	64	Missense	distal	-7	no	16.420	16.399	PhosphoSitePlus	TCGA;ICGC;COSMIC	10.658	Down-regulation
Atypical_PIKK_ATR_ATR_ST	P49006	MARCKSL1	Q13535	ATR	T85	F92L	92	Missense	distal	7	no	11.224	11.324	EPSD	TCGA;ICGC;COSMIC	10.658	Up-regulation
Atypical_PIKK_ATR_ATR_ST	P49006	MARCKSL1	Q13535	ATR	S116	E111V	111	Missense	distal	-5	no	10.725	10.908	EPSD	TCGA;ICGC;COSMIC	10.658	Up-regulation
Atypical_PIKK_ATR_ATR_ST	P49006	MARCKSL1	Q13535	ATR	S116	S117Y	117	Missense	proximal	1	no	10.725	10.388	EPSD	TCGA;ICGC	10.658	Loss
Atypical_PIKK_ATR_ATR_ST	P49006	MARCKSL1	Q13535	ATR	S116	A118V	118	Missense	proximal	2	no	10.725	11.214	EPSD	TCGA;ICGC;COSMIC	10.658	Up-regulation
Atypical_PIKK_ATR_ATR_ST	P49006	MARCKSL1	Q13535	ATR	T178	E183V	183	Missense	distal	5	no	11.017	11.024	EPSD	TCGA;ICGC;COSMIC	10.658	Up-regulation
Atypical_PIKK_ATR_ATR_ST	P49006	MARCKSL1	Q13535	ATR	T178	E183Q	183	Missense	distal	5	no	11.017	11.024	EPSD	TCGA;ICGC;COSMIC	10.658	Up-regulation
Atypical_PIKK_ATR_ATR_ST	P49006	MARCKSL1	Q13535	ATR	T178	P179S	179	Missense	proximal	1	no	11.017	9.908	EPSD	TCGA;ICGC;COSMIC	10.658	Loss
STE_STE20_SLK_STK10_ST	P35241	RDX	O94804	STK10	T66	D69Y	69	Missense	distal	3	no	2.772	2.768	EPSD	TCGA;ICGC	2.434	Down-regulation
STE_STE20_SLK_STK10_ST	P35241	RDX	O94804	STK10	T66	K63T	63	Missense	distal	-3	no	2.772	1.304	EPSD	TCGA;ICGC	2.434	Loss
STE_STE20_SLK_STK10_ST	P35241	RDX	O94804	STK10	T66	K72I	72	Missense	distal	6	no	2.772	2.775	EPSD	TCGA;ICGC;COSMIC	2.434	Up-regulation
STE_STE20_SLK_STK10_ST	P35241	RDX	O94804	STK10	T66	K71R	71	Missense	distal	5	no	2.772	2.749	EPSD	TCGA;ICGC;COSMIC	2.434	Down-regulation
STE_STE20_SLK_STK10_ST	P35241	RDX	O94804	STK10	T564	R569Q	569	Missense	distal	5	no	8.215	8.205	PhosphoSitePlus	TCGA;ICGC	2.434	Down-regulation
STE_STE20_SLK_STK10_ST	P35241	RDX	O94804	STK10	T564	D560Y	560	Missense	distal	-4	no	8.215	7.478	PhosphoSitePlus	TCGA;COSMIC	2.434	Down-regulation
STE_STE20_SLK_STK10_ST	P35241	RDX	O94804	STK10	T564	R566Q	566	Missense	proximal	2	no	8.215	8.201	PhosphoSitePlus	TCGA;COSMIC	2.434	Down-regulation
STE_STE20_SLK_STK10_ST	P35241	RDX	O94804	STK10	T564	A557T	557	Missense	distal	-7	no	8.215	8.159	PhosphoSitePlus	TCGA;ICGC;COSMIC	2.434	Down-regulation
STE_STE20_SLK_STK10_ST	P15311	EZR	O94804	STK10	S66	K60M	60	Missense	distal	-6	no	2.416	2.454	EPSD	TCGA;ICGC;COSMIC	2.434	Gain
STE_STE20_SLK_STK10_ST	P15311	EZR	O94804	STK10	T425	A426V	426	Missense	proximal	1	no	1.946	2.648	EPSD	TCGA;ICGC;COSMIC	2.434	Gain
STE_STE20_SLK_STK10_ST	P15311	EZR	O94804	STK10	T497	A501V	501	Missense	distal	4	no	3.307	3.321	EPSD	TCGA;ICGC	2.434	Up-regulation
STE_STE20_SLK_STK10_ST	P15311	EZR	O94804	STK10	T567	R562Q	562	Missense	distal	-5	no	8.527	8.510	PhosphoSitePlus	TCGA;ICGC	2.434	Down-regulation
STE_STE20_SLK_STK10_ST	P15311	EZR	O94804	STK10	T567	R569Q	569	Missense	proximal	2	no	8.527	8.513	PhosphoSitePlus	TCGA;ICGC;COSMIC	2.434	Down-regulation
STE_STE20_SLK_STK10_ST	P53350	PLK1	O94804	STK10	T210	G213V	213	Missense	distal	3	no	7.551	7.546	PhosphoSitePlus	TCGA;ICGC	2.434	Down-regulation
STE_STE20_SLK_STK10_ST	P53350	PLK1	O94804	STK10	T210	K208E	208	Missense	proximal	-2	no	7.551	7.120	PhosphoSitePlus	TCGA;ICGC;COSMIC	2.434	Down-regulation
STE_STE20_SLK_STK10_ST	P53350	PLK1	O94804	STK10	T210	D204G	204	Missense	distal	-6	no	7.551	7.511	PhosphoSitePlus	TCGA;ICGC;COSMIC	2.434	Down-regulation
STE_STE20_SLK_STK10_ST	P53350	PLK1	O94804	STK10	T341	S335C	335	Missense	distal	-6	no	2.783	2.752	EPSD	TCGA;ICGC;COSMIC	2.434	Down-regulation
STE_STE20_SLK_STK10_ST	P53350	PLK1	O94804	STK10	T341	R337W	337	Missense	distal	-4	no	2.783	2.910	EPSD	TCGA;ICGC;COSMIC	2.434	Up-regulation
STE_STE20_SLK_STK10_ST	P53350	PLK1	O94804	STK10	T341	V342F	342	Missense	proximal	1	no	2.783	2.347	EPSD	TCGA;ICGC	2.434	Loss
STE_STE20_SLK_STK10_ST	P53350	PLK1	O94804	STK10	S578	E575K	575	Missense	distal	-3	no	1.636	2.886	EPSD	TCGA;ICGC;COSMIC	2.434	Gain
STE_STE20_SLK_STK10_ST	P26038	MSN	O94804	STK10	T66	D69N	69	Missense	distal	3	no	2.677	2.679	EPSD	TCGA;ICGC;COSMIC	2.434	Up-regulation
STE_STE20_SLK_STK10_ST	P26038	MSN	O94804	STK10	T66	V65L	65	Missense	proximal	-1	no	2.677	2.797	EPSD	TCGA;ICGC;COSMIC	2.434	Up-regulation
STE_STE20_SLK_STK10_ST	P26038	MSN	O94804	STK10	T66	A67V	67	Missense	proximal	1	no	2.677	3.379	EPSD	TCGA;ICGC	2.434	Up-regulation
STE_STE20_SLK_STK10_ST	P26038	MSN	O94804	STK10	S74	D69N	69	Missense	distal	-5	no	3.891	3.909	EPSD	TCGA;ICGC;COSMIC	2.434	Up-regulation
STE_STE20_SLK_STK10_ST	P26038	MSN	O94804	STK10	S74	A67V	67	Missense	distal	-7	no	3.891	3.815	EPSD	TCGA;ICGC	2.434	Down-regulation
STE_STE20_SLK_STK10_ST	P26038	MSN	O94804	STK10	S207	I208M	208	Missense	proximal	1	no	2.409	2.462	EPSD	TCGA;ICGC;COSMIC	2.434	Gain
STE_STE20_SLK_STK10_ST	P26038	MSN	O94804	STK10	T299	R295S	295	Missense	distal	-4	no	1.647	2.594	EPSD	TCGA;ICGC	2.434	Gain
STE_STE20_SLK_STK10_ST	P26038	MSN	O94804	STK10	T558	R560C	560	Missense	proximal	2	no	8.375	8.356	PhosphoSitePlus	TCGA;ICGC;COSMIC	2.434	Down-regulation
STE_STE20_SLK_STK10_ST	P26038	MSN	O94804	STK10	T558	Q561H	561	Missense	distal	3	no	8.375	8.373	PhosphoSitePlus	TCGA;ICGC;COSMIC	2.434	Down-regulation
STE_STE20_SLK_STK10_ST	P26038	MSN	O94804	STK10	T558	K557N	557	Missense	proximal	-1	no	8.375	8.013	PhosphoSitePlus	TCGA;ICGC	2.434	Down-regulation
STE_STE20_SLK_STK10_ST	P26038	MSN	O94804	STK10	T558	R553Q	553	Missense	distal	-5	no	8.375	8.358	PhosphoSitePlus	TCGA;ICGC	2.434	Down-regulation
TK_Abl_ABL2_Y	P04040	CAT	P42684	ABL2	Y231	G227R	227	Missense	distal	-4	no	36.242	34.722	PhosphoSitePlus;EPSD	TCGA;ICGC;COSMIC	19.113	Down-regulation
TK_Abl_ABL2_Y	P04040	CAT	P42684	ABL2	Y231	H235Y	235	Missense	distal	4	no	36.242	35.587	PhosphoSitePlus;EPSD	TCGA;ICGC;COSMIC	19.113	Down-regulation
TK_Abl_ABL2_Y	P04040	CAT	P42684	ABL2	Y386	P391L	391	Missense	distal	5	no	33.162	35.454	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	19.113	Up-regulation
TK_Abl_ABL2_Y	P04040	CAT	P42684	ABL2	Y386	R380C	380	Missense	distal	-6	no	33.162	32.065	EPSD;PhosphoSitePlus	TCGA;ICGC	19.113	Down-regulation
TK_Abl_ABL2_Y	P42684	ABL2	P42684	ABL2	Y439	A443T	443	Missense	distal	4	no	33.502	33.612	EPSD;PhosphoSitePlus	TCGA;COSMIC;CCLE	19.113	Up-regulation
TK_Abl_ABL2_Y	P42684	ABL2	P42684	ABL2	Y515	E508K	508	Missense	distal	-7	no	18.221	20.012	EPSD	TCGA;COSMIC	19.113	Gain
TK_Abl_ABL2_Y	P42684	ABL2	P42684	ABL2	Y568	S562L	562	Missense	distal	-6	no	34.896	33.259	EPSD	TCGA;COSMIC;CCLE	19.113	Down-regulation
TK_Abl_ABL2_Y	P42684	ABL2	P42684	ABL2	Y568	R571L	571	Missense	distal	3	no	34.896	35.130	EPSD	TCGA;COSMIC	19.113	Up-regulation
TK_Abl_ABL2_Y	P42684	ABL2	P42684	ABL2	Y683	S690L	690	Missense	distal	7	no	36.266	37.370	EPSD	TCGA;COSMIC	19.113	Up-regulation
TK_Abl_ABL2_Y	P42684	ABL2	P42684	ABL2	Y683	E684K	684	Missense	proximal	1	no	36.266	34.615	EPSD	TCGA;COSMIC;CCLE	19.113	Down-regulation
TK_Abl_ABL2_Y	P42684	ABL2	P42684	ABL2	Y683	Q678H	678	Missense	distal	-5	no	36.266	35.040	EPSD	TCGA;COSMIC	19.113	Down-regulation
TK_Abl_ABL2_Y	P01112	HRAS	P42684	ABL2	Y137	A130T	130	Missense	distal	-7	no	31.133	30.825	PhosphoSitePlus	TCGA;ICGC;COSMIC	19.113	Down-regulation
TK_Abl_ABL2_Y	P01112	HRAS	P42684	ABL2	Y137	R135Q	135	Missense	proximal	-2	no	31.133	31.081	PhosphoSitePlus	TCGA;ICGC;COSMIC	19.113	Down-regulation
TK_Abl_ABL2_Y	P01112	HRAS	P42684	ABL2	Y137	A134T	134	Missense	distal	-3	no	31.133	31.130	PhosphoSitePlus	TCGA;ICGC;COSMIC	19.113	Down-regulation
TK_Abl_ABL2_Y	P01112	HRAS	P42684	ABL2	Y137	E143K	143	Missense	distal	6	no	31.133	30.962	PhosphoSitePlus	TCGA;ICGC;COSMIC	19.113	Down-regulation
TK_Abl_ABL2_Y	P46108	CRK	P42684	ABL2	Y239	A240S	240	Missense	proximal	1	no	22.449	24.109	EPSD	TCGA;ICGC;COSMIC	19.113	Up-regulation
TK_Abl_ABL2_Y	P46108	CRK	P42684	ABL2	Y239	R241G	241	Missense	proximal	2	no	22.449	22.383	EPSD	TCGA;ICGC;COSMIC	19.113	Down-regulation
TK_Abl_ABL2_Y	O14818	PSMA7	P42684	ABL2	Y153	S150W	150	Missense	distal	-3	no	35.748	35.847	PhosphoSitePlus	TCGA;COSMIC	19.113	Up-regulation
TK_Abl_ABL2_Y	P17931	LGALS3	P42684	ABL2	Y118	P123S	123	Missense	distal	5	no	37.541	38.330	PhosphoSitePlus;EPSD	TCGA;ICGC	19.113	Up-regulation
TK_Abl_ABL2_Y	P09619	PDGFRB	P42684	ABL2	Y686	G687E	687	Missense	proximal	1	no	32.293	32.455	PhosphoSitePlus	TCGA;ICGC;COSMIC	19.113	Up-regulation
TK_Abl_ABL2_Y	P09619	PDGFRB	P42684	ABL2	Y686	R685C	685	Missense	proximal	-1	no	32.293	23.185	PhosphoSitePlus	TCGA;ICGC;COSMIC;GDSC	19.113	Down-regulation
TK_Abl_ABL2_Y	P09619	PDGFRB	P42684	ABL2	Y686	G687R	687	Missense	proximal	1	no	32.293	30.258	PhosphoSitePlus	TCGA;ICGC;COSMIC	19.113	Down-regulation
TK_Abl_ABL2_Y	P09619	PDGFRB	P42684	ABL2	Y771	D776N	776	Missense	distal	5	no	20.077	21.335	EPSD	TCGA;ICGC;COSMIC	19.113	Up-regulation
TK_Abl_ABL2_Y	P09619	PDGFRB	P42684	ABL2	Y771	Y778C	778	Missense	distal	7	no	20.077	20.280	EPSD	TCGA;ICGC;COSMIC	19.113	Up-regulation
TK_Abl_ABL2_Y	P09619	PDGFRB	P42684	ABL2	Y934	M937T	937	Missense	distal	3	no	26.698	31.217	EPSD	TCGA;ICGC;COSMIC	19.113	Up-regulation
TK_Abl_ABL2_Y	P09619	PDGFRB	P42684	ABL2	Y934	C940Y	940	Missense	distal	6	no	26.698	26.634	EPSD	TCGA;ICGC;COSMIC	19.113	Down-regulation
TK_Abl_ABL2_Y	P09619	PDGFRB	P42684	ABL2	Y970	K968N	968	Missense	proximal	-2	no	28.921	28.668	EPSD	TCGA;ICGC;COSMIC	19.113	Down-regulation
TK_Abl_ABL2_Y	P09619	PDGFRB	P42684	ABL2	Y970	Q971K	971	Missense	proximal	1	no	28.921	27.582	EPSD	TCGA;ICGC;COSMIC	19.113	Down-regulation
TK_Abl_ABL2_Y	P05556	ITGB1	P42684	ABL2	Y783	T777M	777	Missense	distal	-6	no	26.275	24.591	PhosphoSitePlus	TCGA;ICGC;COSMIC	19.113	Down-regulation
TK_Abl_ABL2_Y	P05556	ITGB1	P42684	ABL2	Y783	P781S	781	Missense	proximal	-2	no	26.275	26.469	PhosphoSitePlus	TCGA;ICGC;COSMIC	19.113	Up-regulation
TK_Abl_ABL2_Y	P05556	ITGB1	P42684	ABL2	Y783	T789I	789	Missense	distal	6	no	26.275	25.995	PhosphoSitePlus	TCGA;ICGC;COSMIC	19.113	Down-regulation
TK_Abl_ABL2_Y	P05556	ITGB1	P42684	ABL2	Y783	T777A	777	Missense	distal	-6	no	26.275	25.693	PhosphoSitePlus	TCGA;ICGC;COSMIC	19.113	Down-regulation
TK_Abl_ABL2_Y	O15304	SIVA1	P42684	ABL2	Y34	E32K	32	Missense	proximal	-2	no	32.693	32.820	PhosphoSitePlus	TCGA;ICGC;COSMIC	19.113	Up-regulation
TKL_LISK_LIMK_LIMK1_ST	P23528	CFL1	P53667	LIMK1	S3	D9N	9	Missense	distal	6	no	3.972	3.304	PhosphoSitePlus	TCGA;COSMIC	-0.776	Down-regulation
TK_Src_SrcB_HCK_Y	Q92556	ELMO1	P08631	HCK	Y18	P15L	15	Missense	distal	-3	no	10.836	9.141	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	7.597	Down-regulation
TK_Src_SrcB_HCK_Y	Q92556	ELMO1	P08631	HCK	Y18	A11T	11	Missense	distal	-7	no	10.836	9.027	EPSD;PhosphoSitePlus	TCGA;ICGC	7.597	Down-regulation
TK_Src_SrcB_HCK_Y	Q92556	ELMO1	P08631	HCK	Y216	Q221R	221	Missense	distal	5	no	10.924	10.306	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	7.597	Down-regulation
TK_Src_SrcB_HCK_Y	Q92556	ELMO1	P08631	HCK	Y216	A220V	220	Missense	distal	4	no	10.924	10.135	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	7.597	Down-regulation
TK_Src_SrcB_HCK_Y	Q92556	ELMO1	P08631	HCK	Y216	A220E	220	Missense	distal	4	no	10.924	9.357	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	7.597	Down-regulation
TK_Src_SrcB_HCK_Y	Q92556	ELMO1	P08631	HCK	Y216	A220S	220	Missense	distal	4	no	10.924	10.170	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	7.597	Down-regulation
TK_Src_SrcB_HCK_Y	Q92556	ELMO1	P08631	HCK	Y216	S212N	212	Missense	distal	-4	no	10.924	10.896	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	7.597	Down-regulation
TK_Src_SrcB_HCK_Y	Q92556	ELMO1	P08631	HCK	Y395	A388T	388	Missense	distal	-7	no	11.625	9.816	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	7.597	Down-regulation
TK_Src_SrcB_HCK_Y	Q92556	ELMO1	P08631	HCK	Y395	E401D	401	Missense	distal	6	no	11.625	11.288	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	7.597	Down-regulation
TK_Src_SrcB_HCK_Y	Q92556	ELMO1	P08631	HCK	Y395	H391N	391	Missense	distal	-4	no	11.625	11.601	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	7.597	Down-regulation
TK_Src_SrcB_HCK_Y	Q92556	ELMO1	P08631	HCK	Y395	Q392K	392	Missense	distal	-3	no	11.625	12.014	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	7.597	Up-regulation
TK_Src_SrcB_HCK_Y	Q92556	ELMO1	P08631	HCK	Y511	R518C	518	Missense	distal	7	no	10.557	10.338	EPSD;PhosphoSitePlus	TCGA;COSMIC	7.597	Down-regulation
TK_Src_SrcB_HCK_Y	Q92556	ELMO1	P08631	HCK	Y511	T512N	512	Missense	proximal	1	no	10.557	10.496	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	7.597	Down-regulation
TK_Src_SrcB_HCK_Y	Q92556	ELMO1	P08631	HCK	Y511	E513K	513	Missense	proximal	2	no	10.557	10.419	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	7.597	Down-regulation
TK_Src_SrcB_HCK_Y	Q92556	ELMO1	P08631	HCK	Y511	E513Q	513	Missense	proximal	2	no	10.557	10.289	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	7.597	Down-regulation
TK_Src_SrcB_HCK_Y	Q92556	ELMO1	P08631	HCK	Y511	R518H	518	Missense	distal	7	no	10.557	10.509	EPSD;PhosphoSitePlus	TCGA	7.597	Down-regulation
TK_Src_SrcB_HCK_Y	P08631	HCK	P08631	HCK	Y51	V52L	52	Missense	proximal	1	no	11.142	11.183	EPSD	TCGA;ICGC;COSMIC	7.597	Up-regulation
TK_Src_SrcB_HCK_Y	P08631	HCK	P08631	HCK	Y51	D54Y	54	Missense	distal	3	no	11.142	9.901	EPSD	TCGA;ICGC;COSMIC	7.597	Down-regulation
TK_Src_SrcB_HCK_Y	P08631	HCK	P08631	HCK	Y51	P49H	49	Missense	proximal	-2	no	11.142	11.259	EPSD	TCGA;ICGC;COSMIC	7.597	Up-regulation
TK_Src_SrcB_HCK_Y	P08631	HCK	P08631	HCK	Y51	P53R	53	Missense	proximal	2	no	11.142	11.279	EPSD	TCGA;ICGC;COSMIC	7.597	Up-regulation
TK_Src_SrcB_HCK_Y	P08631	HCK	P08631	HCK	Y209	G206R	206	Missense	distal	-3	no	10.258	6.409	EPSD	TCGA;COSMIC	7.597	Loss
TK_Src_SrcB_HCK_Y	P08631	HCK	P08631	HCK	Y209	R213Q	213	Missense	distal	4	no	10.258	10.045	EPSD	TCGA	7.597	Down-regulation
TK_Src_SrcB_HCK_Y	P08631	HCK	P08631	HCK	Y209	S211F	211	Missense	proximal	2	no	10.258	9.749	EPSD	TCGA;COSMIC	7.597	Down-regulation
TK_Src_SrcB_HCK_Y	P08631	HCK	P08631	HCK	Y209	S214R	214	Missense	distal	5	no	10.258	9.565	EPSD	TCGA;COSMIC	7.597	Down-regulation
TK_Src_SrcB_HCK_Y	P08631	HCK	P08631	HCK	Y209	G206E	206	Missense	distal	-3	no	10.258	8.516	EPSD	TCGA;COSMIC	7.597	Down-regulation
TK_Src_SrcB_HCK_Y	P08631	HCK	P08631	HCK	Y411	R404Q	404	Missense	distal	-7	no	11.136	10.862	PhosphoSitePlus;EPSD	TCGA;COSMIC	7.597	Down-regulation
TK_Src_SrcB_HCK_Y	P08631	HCK	P08631	HCK	Y411	R414W	414	Missense	distal	3	no	11.136	9.536	PhosphoSitePlus;EPSD	TCGA;COSMIC	7.597	Down-regulation
TK_Src_SrcB_HCK_Y	P08631	HCK	P08631	HCK	Y411	A413T	413	Missense	proximal	2	no	11.136	10.849	PhosphoSitePlus;EPSD	TCGA;COSMIC	7.597	Down-regulation
TK_Src_SrcB_HCK_Y	P08631	HCK	P08631	HCK	Y411	R404W	404	Missense	distal	-7	no	11.136	9.021	PhosphoSitePlus;EPSD	TCGA;COSMIC	7.597	Down-regulation
TK_Src_SrcB_HCK_Y	P08631	HCK	P08631	HCK	Y411	Y411C	411	Missense	central	0	yes	11.136	0.000	PhosphoSitePlus;EPSD	TCGA	7.597	Loss
TK_Src_SrcB_HCK_Y	P08631	HCK	P08631	HCK	Y411	T412M	412	Missense	proximal	1	no	11.136	11.101	PhosphoSitePlus;EPSD	TCGA;COSMIC	7.597	Down-regulation
TK_Src_SrcB_HCK_Y	P42229	STAT5A	P08631	HCK	Y694	Q698P	698	Missense	distal	4	no	11.334	11.104	PhosphoSitePlus	TCGA;ICGC	7.597	Down-regulation
TK_Src_SrcB_HCK_Y	Q13444	ADAM15	P08631	HCK	Y715	Y715H	715	Missense	central	0	yes	11.829	0.000	PhosphoSitePlus	TCGA;COSMIC	7.597	Loss
TK_Src_SrcB_HCK_Y	Q13444	ADAM15	P08631	HCK	Y715	R720H	720	Missense	distal	5	no	11.829	12.345	PhosphoSitePlus	TCGA	7.597	Up-regulation
TK_Src_SrcB_HCK_Y	Q13444	ADAM15	P08631	HCK	Y735	S740F	740	Missense	distal	5	no	10.220	9.388	EPSD	TCGA;COSMIC	7.597	Down-regulation
TK_Src_SrcB_HCK_Y	Q13444	ADAM15	P08631	HCK	Y735	A738S	738	Missense	distal	3	no	10.220	10.459	EPSD	TCGA;COSMIC	7.597	Up-regulation
TK_Src_SrcB_HCK_Y	P51692	STAT5B	P08631	HCK	Y699	A695T	695	Missense	distal	-4	no	11.353	11.284	PhosphoSitePlus	TCGA	7.597	Down-regulation
TK_Src_SrcB_HCK_Y	P51692	STAT5B	P08631	HCK	Y699	I704T	704	Missense	distal	5	no	11.353	11.658	PhosphoSitePlus	TCGA;ICGC;COSMIC	7.597	Up-regulation
TK_Src_SrcB_HCK_Y	P51692	STAT5B	P08631	HCK	Y699	V700L	700	Missense	proximal	1	no	11.353	11.393	PhosphoSitePlus	TCGA;ICGC;COSMIC	7.597	Up-regulation
TK_Src_SrcB_HCK_Y	P51692	STAT5B	P08631	HCK	Y699	A695V	695	Missense	distal	-4	no	11.353	11.287	PhosphoSitePlus	TCGA;ICGC;COSMIC	7.597	Down-regulation
TK_Src_SrcB_HCK_Y	O15350	TP73	P08631	HCK	Y28	S34L	34	Missense	distal	6	no	10.670	10.618	PhosphoSitePlus	TCGA;ICGC;COSMIC	7.597	Down-regulation
TK_Src_SrcB_HCK_Y	Q9UHD2	TBK1	P08631	HCK	Y354	E355K	355	Missense	proximal	1	no	10.303	10.347	PhosphoSitePlus;EPSD	TCGA;ICGC;COSMIC	7.597	Up-regulation
TKL_MLK_MLK_MAP3K11_ST	Q16584	MAP3K11	Q16584	MAP3K11	T277	A282V	282	Missense	distal	5	no	4.223	4.228	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	1.264	Up-regulation
TKL_MLK_MLK_MAP3K11_ST	Q16584	MAP3K11	Q16584	MAP3K11	S281	A282V	282	Missense	proximal	1	no	4.392	4.409	PhosphoSitePlus;EPSD	TCGA;ICGC;COSMIC	1.264	Up-regulation
TKL_MLK_MLK_MAP3K11_ST	P46734	MAP2K3	Q16584	MAP3K11	S31	P38T	38	Missense	distal	7	no	1.101	1.337	EPSD	TCGA;COSMIC	1.264	Gain
TKL_MLK_MLK_MAP3K11_ST	P46734	MAP2K3	Q16584	MAP3K11	S31	P38L	38	Missense	distal	7	no	1.101	1.435	EPSD	TCGA	1.264	Gain
TKL_MLK_MLK_MAP3K11_ST	P46734	MAP2K3	Q16584	MAP3K11	S218	M223I	223	Missense	distal	5	no	4.316	4.318	PhosphoSitePlus;EPSD	TCGA;COSMIC	1.264	Up-regulation
TKL_MLK_MLK_MAP3K11_ST	P46734	MAP2K3	Q16584	MAP3K11	S218	A225V	225	Missense	distal	7	no	4.316	4.234	PhosphoSitePlus;EPSD	TCGA;COSMIC	1.264	Down-regulation
TKL_MLK_MLK_MAP3K11_ST	P46734	MAP2K3	Q16584	MAP3K11	S218	S218Y	218	Missense	central	0	yes	4.316	0.000	PhosphoSitePlus;EPSD	TCGA;CCLE	1.264	Loss
TKL_MLK_MLK_MAP3K11_ST	P46734	MAP2K3	Q16584	MAP3K11	S218	S212N	212	Missense	distal	-6	no	4.316	4.275	PhosphoSitePlus;EPSD	TCGA;COSMIC	1.264	Down-regulation
TKL_MLK_MLK_MAP3K11_ST	P46734	MAP2K3	Q16584	MAP3K11	T222	M223I	223	Missense	proximal	1	no	4.657	4.669	EPSD;PhosphoSitePlus	TCGA;COSMIC	1.264	Up-regulation
TKL_MLK_MLK_MAP3K11_ST	P46734	MAP2K3	Q16584	MAP3K11	T222	C227F	227	Missense	distal	5	no	4.657	4.679	EPSD;PhosphoSitePlus	TCGA;COSMIC	1.264	Up-regulation
TKL_MLK_MLK_MAP3K11_ST	P46734	MAP2K3	Q16584	MAP3K11	T222	P229S	229	Missense	distal	7	no	4.657	4.687	EPSD;PhosphoSitePlus	TCGA;COSMIC	1.264	Up-regulation
TKL_MLK_MLK_MAP3K11_ST	P46734	MAP2K3	Q16584	MAP3K11	T222	A225V	225	Missense	distal	3	no	4.657	4.672	EPSD;PhosphoSitePlus	TCGA;COSMIC	1.264	Up-regulation
TKL_MLK_MLK_MAP3K11_ST	P46734	MAP2K3	Q16584	MAP3K11	T222	S218Y	218	Missense	distal	-4	no	4.657	4.673	EPSD;PhosphoSitePlus	TCGA;CCLE	1.264	Up-regulation
TKL_MLK_MLK_MAP3K11_ST	Q13526	PIN1	Q16584	MAP3K11	S38	R36P	36	Missense	proximal	-2	no	1.363	1.283	EPSD	TCGA;ICGC;COSMIC	1.264	Down-regulation
TKL_MLK_MLK_MAP3K11_ST	Q13526	PIN1	Q16584	MAP3K11	S38	G39C	39	Missense	proximal	1	no	1.363	1.385	EPSD	TCGA;ICGC;COSMIC	1.264	Up-regulation
TKL_MLK_MLK_MAP3K11_ST	Q13526	PIN1	Q16584	MAP3K11	S108	S105F	105	Missense	distal	-3	no	2.412	2.460	EPSD	TCGA;ICGC;COSMIC	1.264	Up-regulation
TKL_MLK_MLK_MAP3K11_ST	Q13526	PIN1	Q16584	MAP3K11	S108	D112N	112	Missense	distal	4	no	2.412	2.309	EPSD	TCGA;ICGC;COSMIC	1.264	Down-regulation
TKL_MLK_MLK_MAP3K11_ST	Q13526	PIN1	Q16584	MAP3K11	S108	E104K	104	Missense	distal	-4	no	2.412	2.393	EPSD	TCGA;ICGC;COSMIC	1.264	Down-regulation
TKL_MLK_MLK_MAP3K11_ST	Q13526	PIN1	Q16584	MAP3K11	S108	Q109R	109	Missense	proximal	1	no	2.412	2.402	EPSD	TCGA;ICGC	1.264	Down-regulation
TKL_MLK_MLK_MAP3K11_ST	Q13526	PIN1	Q16584	MAP3K11	S138	T143M	143	Missense	distal	5	no	3.911	3.909	PhosphoSitePlus	TCGA	1.264	Down-regulation
TKL_MLK_MLK_MAP3K11_ST	Q13526	PIN1	Q16584	MAP3K11	S138	F139S	139	Missense	proximal	1	no	3.911	3.935	PhosphoSitePlus	TCGA;ICGC;COSMIC	1.264	Up-regulation
TKL_MLK_MLK_MAP3K11_ST	Q13526	PIN1	Q16584	MAP3K11	S138	E145K	145	Missense	distal	7	no	3.911	3.767	PhosphoSitePlus	TCGA;ICGC;COSMIC	1.264	Down-regulation
TKL_MLK_MLK_MAP3K11_ST	Q13526	PIN1	Q16584	MAP3K11	S138	R142L	142	Missense	distal	4	no	3.911	3.795	PhosphoSitePlus	TCGA;ICGC;COSMIC	1.264	Down-regulation
TKL_MLK_MLK_MAP3K11_ST	Q13526	PIN1	Q16584	MAP3K11	S138	A137T	137	Missense	proximal	-1	no	3.911	3.753	PhosphoSitePlus	TCGA;ICGC;GDSC;CCLE	1.264	Down-regulation
TKL_MLK_MLK_MAP3K11_ST	Q13526	PIN1	Q16584	MAP3K11	S147	T143M	143	Missense	distal	-4	no	1.655	1.669	EPSD	TCGA	1.264	Up-regulation
TKL_MLK_MLK_MAP3K11_ST	Q13526	PIN1	Q16584	MAP3K11	S147	E145K	145	Missense	proximal	-2	no	1.655	1.989	EPSD	TCGA;ICGC;COSMIC	1.264	Up-regulation
TKL_MLK_MLK_MAP3K11_ST	Q13526	PIN1	Q16584	MAP3K11	S147	S154F	154	Missense	distal	7	no	1.655	2.112	EPSD	TCGA;ICGC;COSMIC	1.264	Up-regulation
TKL_MLK_MLK_MAP3K11_ST	Q13526	PIN1	Q16584	MAP3K11	S147	G148R	148	Missense	proximal	1	no	1.655	1.649	EPSD	TCGA;ICGC;COSMIC	1.264	Down-regulation
TKL_MLK_MLK_MAP3K11_ST	Q13526	PIN1	Q16584	MAP3K11	S147	R142L	142	Missense	distal	-5	no	1.655	1.658	EPSD	TCGA;ICGC;COSMIC	1.264	Up-regulation
TKL_MLK_MLK_MAP3K11_ST	Q13526	PIN1	Q16584	MAP3K11	T152	E145K	145	Missense	distal	-7	no	1.711	1.728	EPSD	TCGA;ICGC;COSMIC	1.264	Up-regulation
TKL_MLK_MLK_MAP3K11_ST	Q13526	PIN1	Q16584	MAP3K11	T152	S154F	154	Missense	proximal	2	no	1.711	1.615	EPSD	TCGA;ICGC;COSMIC	1.264	Down-regulation
TKL_MLK_MLK_MAP3K11_ST	Q13526	PIN1	Q16584	MAP3K11	T152	G148R	148	Missense	distal	-4	no	1.711	1.733	EPSD	TCGA;ICGC;COSMIC	1.264	Up-regulation
TKL_MLK_MLK_MAP3K11_ST	Q13131	PRKAA1	Q16584	MAP3K11	S65	S65N	65	Missense	central	0	yes	1.690	0.000	EPSD	TCGA;ICGC;COSMIC	1.264	Loss
TKL_MLK_MLK_MAP3K11_ST	Q13131	PRKAA1	Q16584	MAP3K11	S65	G70E	70	Missense	distal	5	no	1.690	1.678	EPSD	TCGA;ICGC;COSMIC	1.264	Down-regulation
TKL_MLK_MLK_MAP3K11_ST	P45985	MAP2K4	Q16584	MAP3K11	S80	S80N	80	Missense	central	0	yes	1.301	0.000	EPSD	TCGA;COSMIC	1.264	Loss
TKL_MLK_MLK_MAP3K11_ST	P45985	MAP2K4	Q16584	MAP3K11	S80	S83A	83	Missense	distal	3	no	1.301	1.576	EPSD	TCGA	1.264	Up-regulation
TKL_MLK_MLK_MAP3K11_ST	P45985	MAP2K4	Q16584	MAP3K11	S90	S83A	83	Missense	distal	-7	no	1.321	1.331	EPSD	TCGA	1.264	Up-regulation
TKL_MLK_MLK_MAP3K11_ST	P45985	MAP2K4	Q16584	MAP3K11	S90	S90F	90	Missense	central	0	yes	1.321	0.000	EPSD	TCGA;COSMIC	1.264	Loss
TKL_MLK_MLK_MAP3K11_ST	P45985	MAP2K4	Q16584	MAP3K11	S257	S257F	257	Missense	central	0	yes	4.462	0.000	PhosphoSitePlus;EPSD	TCGA;COSMIC	1.264	Loss
TKL_MLK_MLK_MAP3K11_ST	P45985	MAP2K4	Q16584	MAP3K11	S257	S251I	251	Missense	distal	-6	no	4.462	4.505	PhosphoSitePlus;EPSD	TCGA;COSMIC	1.264	Up-regulation
TKL_MLK_MLK_MAP3K11_ST	P45985	MAP2K4	Q16584	MAP3K11	T261	S257F	257	Missense	distal	-4	no	4.420	4.423	EPSD;PhosphoSitePlus	TCGA;COSMIC	1.264	Up-regulation
TKL_MLK_MLK_MAP3K11_ST	P45985	MAP2K4	Q16584	MAP3K11	T261	R262K	262	Missense	proximal	1	no	4.420	4.473	EPSD;PhosphoSitePlus	TCGA;COSMIC	1.264	Up-regulation
TKL_MLK_MLK_MAP3K11_ST	P45985	MAP2K4	Q16584	MAP3K11	T261	G265C	265	Missense	distal	4	no	4.420	4.414	EPSD;PhosphoSitePlus	TCGA;COSMIC	1.264	Down-regulation
Atypical_PDHK_PDHK_PDK3_ST	P29803	PDHA2	Q15120	PDK3	S128	Y123C	123	Missense	distal	-5	no	1.673	1.830	EPSD	TCGA;ICGC;COSMIC	1.746	Gain
Atypical_PDHK_PDHK_PDK3_ST	P29803	PDHA2	Q15120	PDK3	T231	G228V	228	Missense	distal	-3	no	2.638	2.439	EPSD	TCGA;ICGC;COSMIC	1.746	Down-regulation
Atypical_PDHK_PDHK_PDK3_ST	P29803	PDHA2	Q15120	PDK3	T231	Y225F	225	Missense	distal	-6	no	2.638	2.176	EPSD	TCGA;ICGC;COSMIC	1.746	Down-regulation
Atypical_PDHK_PDHK_PDK3_ST	P29803	PDHA2	Q15120	PDK3	T231	Y225C	225	Missense	distal	-6	no	2.638	2.195	EPSD	TCGA;ICGC;COSMIC	1.746	Down-regulation
Atypical_PDHK_PDHK_PDK3_ST	P29803	PDHA2	Q15120	PDK3	T231	E232V	232	Missense	proximal	1	no	2.638	2.602	EPSD	TCGA;ICGC;COSMIC	1.746	Down-regulation
Atypical_PDHK_PDHK_PDK3_ST	P29803	PDHA2	Q15120	PDK3	T231	G226R	226	Missense	distal	-5	no	2.638	2.806	EPSD	TCGA;ICGC;COSMIC	1.746	Up-regulation
Atypical_PDHK_PDHK_PDK3_ST	P29803	PDHA2	Q15120	PDK3	T231	R233K	233	Missense	proximal	2	no	2.638	1.490	EPSD	TCGA;ICGC;COSMIC	1.746	Loss
Atypical_PDHK_PDHK_PDK3_ST	P29803	PDHA2	Q15120	PDK3	T284	Y285H	285	Missense	proximal	1	no	1.777	1.005	EPSD	TCGA;ICGC;COSMIC	1.746	Loss
Atypical_PDHK_PDHK_PDK3_ST	P29803	PDHA2	Q15120	PDK3	T284	M280I	280	Missense	distal	-4	no	1.777	1.702	EPSD	TCGA;ICGC;COSMIC	1.746	Loss
Atypical_PDHK_PDHK_PDK3_ST	P29803	PDHA2	Q15120	PDK3	S291	Y285H	285	Missense	distal	-6	no	10.124	9.817	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	1.746	Down-regulation
Atypical_PDHK_PDHK_PDK3_ST	P29803	PDHA2	Q15120	PDK3	S291	M292I	292	Missense	proximal	1	no	10.124	9.251	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	1.746	Down-regulation
Atypical_PDHK_PDHK_PDK3_ST	P29803	PDHA2	Q15120	PDK3	S291	S298C	298	Missense	distal	7	no	10.124	9.925	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	1.746	Down-regulation
Atypical_PDHK_PDHK_PDK3_ST	P29803	PDHA2	Q15120	PDK3	S291	S293T	293	Missense	proximal	2	no	10.124	9.656	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	1.746	Down-regulation
Atypical_PDHK_PDHK_PDK3_ST	P29803	PDHA2	Q15120	PDK3	S293	R300C	300	Missense	distal	7	no	2.409	2.393	EPSD	TCGA;ICGC;COSMIC	1.746	Down-regulation
Atypical_PDHK_PDHK_PDK3_ST	P29803	PDHA2	Q15120	PDK3	S293	R300H	300	Missense	distal	7	no	2.409	2.356	EPSD	TCGA;ICGC;COSMIC;CCLE	1.746	Down-regulation
Atypical_PDHK_PDHK_PDK3_ST	P29803	PDHA2	Q15120	PDK3	S293	M292I	292	Missense	proximal	-1	no	2.409	2.394	EPSD	TCGA;ICGC;COSMIC	1.746	Down-regulation
Atypical_PDHK_PDHK_PDK3_ST	P29803	PDHA2	Q15120	PDK3	S293	R300S	300	Missense	distal	7	no	2.409	2.593	EPSD	TCGA;ICGC;COSMIC	1.746	Up-regulation
Atypical_PDHK_PDHK_PDK3_ST	P29803	PDHA2	Q15120	PDK3	S293	R300L	300	Missense	distal	7	no	2.409	2.269	EPSD	TCGA;ICGC;COSMIC	1.746	Down-regulation
Atypical_PDHK_PDHK_PDK3_ST	P29803	PDHA2	Q15120	PDK3	S293	S298C	298	Missense	distal	5	no	2.409	1.932	EPSD	TCGA;ICGC;COSMIC	1.746	Down-regulation
Atypical_PDHK_PDHK_PDK3_ST	P29803	PDHA2	Q15120	PDK3	S298	R300C	300	Missense	proximal	2	no	9.541	8.520	PhosphoSitePlus;EPSD	TCGA;ICGC;COSMIC	1.746	Down-regulation
Atypical_PDHK_PDHK_PDK3_ST	P29803	PDHA2	Q15120	PDK3	S298	R302Q	302	Missense	distal	4	no	9.541	9.550	PhosphoSitePlus;EPSD	TCGA;ICGC;COSMIC	1.746	Up-regulation
Atypical_PDHK_PDHK_PDK3_ST	P29803	PDHA2	Q15120	PDK3	S298	R300H	300	Missense	proximal	2	no	9.541	8.605	PhosphoSitePlus;EPSD	TCGA;ICGC;COSMIC;CCLE	1.746	Down-regulation
Atypical_PDHK_PDHK_PDK3_ST	P29803	PDHA2	Q15120	PDK3	S298	M292I	292	Missense	distal	-6	no	9.541	9.061	PhosphoSitePlus;EPSD	TCGA;ICGC;COSMIC	1.746	Down-regulation
Atypical_PDHK_PDHK_PDK3_ST	P29803	PDHA2	Q15120	PDK3	S298	R300S	300	Missense	proximal	2	no	9.541	9.171	PhosphoSitePlus;EPSD	TCGA;ICGC;COSMIC	1.746	Down-regulation
Atypical_PDHK_PDHK_PDK3_ST	P29803	PDHA2	Q15120	PDK3	S298	R300L	300	Missense	proximal	2	no	9.541	8.487	PhosphoSitePlus;EPSD	TCGA;ICGC;COSMIC	1.746	Down-regulation
Atypical_PDHK_PDHK_PDK3_ST	P29803	PDHA2	Q15120	PDK3	S298	S298C	298	Missense	central	0	yes	9.541	0.000	PhosphoSitePlus;EPSD	TCGA;ICGC;COSMIC	1.746	Loss
Atypical_PDHK_PDHK_PDK3_ST	P29803	PDHA2	Q15120	PDK3	S298	S293T	293	Missense	distal	-5	no	9.541	9.072	PhosphoSitePlus;EPSD	TCGA;ICGC;COSMIC	1.746	Down-regulation
Atypical_PDHK_PDHK_PDK3_ST	P29803	PDHA2	Q15120	PDK3	S310	V308I	308	Missense	proximal	-2	no	1.993	2.091	EPSD	TCGA;ICGC;COSMIC	1.746	Up-regulation
Atypical_PDHK_PDHK_PDK3_ST	P29803	PDHA2	Q15120	PDK3	S310	K311N	311	Missense	proximal	1	no	1.993	1.979	EPSD	TCGA;ICGC;COSMIC	1.746	Down-regulation
Atypical_PDHK_PDHK_PDK3_ST	P29803	PDHA2	Q15120	PDK3	S310	R312S	312	Missense	proximal	2	no	1.993	1.623	EPSD	TCGA;ICGC;COSMIC	1.746	Loss
Atypical_PDHK_PDHK_PDK3_ST	P29803	PDHA2	Q15120	PDK3	S310	D313Y	313	Missense	distal	3	no	1.993	1.951	EPSD	TCGA;ICGC;COSMIC	1.746	Down-regulation
Atypical_PDHK_PDHK_PDK3_ST	P29803	PDHA2	Q15120	PDK3	S310	V308G	308	Missense	proximal	-2	no	1.993	2.988	EPSD	TCGA;ICGC;COSMIC	1.746	Up-regulation
AGC_DMPK_ROCK_ROCK2_ST	P19634	SLC9A1	O75116	ROCK2	S18	R14W	14	Missense	distal	-4	no	23.187	22.232	EPSD	TCGA;COSMIC	20.789	Down-regulation
AGC_DMPK_ROCK_ROCK2_ST	P19634	SLC9A1	O75116	ROCK2	S18	F16I	16	Missense	proximal	-2	no	23.187	17.582	EPSD	TCGA;ICGC;COSMIC	20.789	Loss
AGC_DMPK_ROCK_ROCK2_ST	P19634	SLC9A1	O75116	ROCK2	S18	V22A	22	Missense	distal	4	no	23.187	23.059	EPSD	TCGA;ICGC;COSMIC	20.789	Down-regulation
AGC_DMPK_ROCK_ROCK2_ST	P19634	SLC9A1	O75116	ROCK2	T653	T653M	653	Missense	central	0	yes	28.935	0.000	PhosphoSitePlus	TCGA;ICGC;COSMIC	20.789	Loss
AGC_DMPK_ROCK_ROCK2_ST	P19634	SLC9A1	O75116	ROCK2	S703	R698P	698	Missense	distal	-5	no	20.803	18.887	EPSD	TCGA;ICGC;COSMIC	20.789	Loss
AGC_DMPK_ROCK_ROCK2_ST	P19634	SLC9A1	O75116	ROCK2	S703	S703L	703	Missense	central	0	yes	20.803	0.000	EPSD	TCGA;ICGC;COSMIC	20.789	Loss
AGC_DMPK_ROCK_ROCK2_ST	P19634	SLC9A1	O75116	ROCK2	S766	S770L	770	Missense	distal	4	no	25.432	25.770	EPSD	TCGA;COSMIC	20.789	Up-regulation
AGC_DMPK_ROCK_ROCK2_ST	P19634	SLC9A1	O75116	ROCK2	S766	R765W	765	Missense	proximal	-1	no	25.432	24.966	EPSD	TCGA;ICGC;COSMIC;GDSC	20.789	Down-regulation
AGC_DMPK_ROCK_ROCK2_ST	P56817	BACE1	O75116	ROCK2	T47	P44S	44	Missense	distal	-3	no	22.784	21.131	EPSD	TCGA;ICGC;COSMIC	20.789	Down-regulation
AGC_DMPK_ROCK_ROCK2_ST	P56817	BACE1	O75116	ROCK2	S59	E62G	62	Missense	distal	3	no	23.679	23.985	EPSD	TCGA;ICGC;COSMIC	20.789	Up-regulation
AGC_DMPK_ROCK_ROCK2_ST	Q92673	SORL1	O75116	ROCK2	S732	K730E	730	Missense	proximal	-2	no	33.466	28.895	EPSD	TCGA;ICGC;COSMIC	20.789	Down-regulation
AGC_DMPK_ROCK_ROCK2_ST	Q92673	SORL1	O75116	ROCK2	S732	G727S	727	Missense	distal	-5	no	33.466	32.641	EPSD	TCGA;ICGC;COSMIC	20.789	Down-regulation
AGC_DMPK_ROCK_ROCK2_ST	Q92673	SORL1	O75116	ROCK2	S1174	S1173F	1173	Missense	proximal	-1	no	26.470	26.201	EPSD	TCGA;COSMIC	20.789	Down-regulation
AGC_DMPK_ROCK_ROCK2_ST	Q92673	SORL1	O75116	ROCK2	S1174	R1172C	1172	Missense	proximal	-2	no	26.470	3.066	EPSD	TCGA;COSMIC	20.789	Loss
AGC_DMPK_ROCK_ROCK2_ST	Q92673	SORL1	O75116	ROCK2	S1174	G1179R	1179	Missense	distal	5	no	26.470	26.136	EPSD	TCGA	20.789	Down-regulation
AGC_DMPK_ROCK_ROCK2_ST	Q92673	SORL1	O75116	ROCK2	T1612	S1607T	1607	Missense	distal	-5	no	20.651	22.227	EPSD	TCGA;COSMIC	20.789	Gain
AGC_DMPK_ROCK_ROCK2_ST	Q92673	SORL1	O75116	ROCK2	T1612	T1605I	1605	Missense	distal	-7	no	20.651	20.998	EPSD	TCGA;COSMIC	20.789	Gain
AGC_DMPK_ROCK_ROCK2_ST	Q92673	SORL1	O75116	ROCK2	S1984	V1982A	1982	Missense	proximal	-2	no	18.305	29.385	EPSD	TCGA	20.789	Gain
AGC_DMPK_ROCK_ROCK2_ST	Q92673	SORL1	O75116	ROCK2	S1987	R1985C	1985	Missense	proximal	-2	no	24.100	0.696	EPSD	TCGA;COSMIC	20.789	Loss
AGC_DMPK_ROCK_ROCK2_ST	Q92673	SORL1	O75116	ROCK2	S1987	R1985H	1985	Missense	proximal	-2	no	24.100	15.327	EPSD	TCGA;COSMIC;GDSC	20.789	Loss
AGC_DMPK_ROCK_ROCK2_ST	Q92673	SORL1	O75116	ROCK2	S1987	V1982A	1982	Missense	distal	-5	no	24.100	28.421	EPSD	TCGA	20.789	Up-regulation
AGC_DMPK_ROCK_ROCK2_ST	Q92673	SORL1	O75116	ROCK2	S2178	S2175R	2175	Missense	distal	-3	no	19.202	33.105	EPSD	TCGA;COSMIC	20.789	Gain
AGC_DMPK_ROCK_ROCK2_ST	Q92673	SORL1	O75116	ROCK2	S2179	Y2177H	2177	Missense	proximal	-2	no	21.926	20.959	EPSD	TCGA;COSMIC	20.789	Down-regulation
AGC_DMPK_ROCK_ROCK2_ST	Q92673	SORL1	O75116	ROCK2	S2179	A2173S	2173	Missense	distal	-6	no	21.926	22.435	EPSD	TCGA;COSMIC	20.789	Up-regulation
AGC_DMPK_ROCK_ROCK2_ST	Q92673	SORL1	O75116	ROCK2	S2179	S2175R	2175	Missense	distal	-4	no	21.926	22.243	EPSD	TCGA;COSMIC	20.789	Up-regulation
AGC_DMPK_ROCK_ROCK2_ST	Q92673	SORL1	O75116	ROCK2	S2179	R2180S	2180	Missense	proximal	1	no	21.926	22.040	EPSD	TCGA;COSMIC	20.789	Up-regulation
AGC_DMPK_ROCK_ROCK2_ST	Q92673	SORL1	O75116	ROCK2	S2179	F2186V	2186	Missense	distal	7	no	21.926	20.690	EPSD	TCGA	20.789	Loss
AGC_DMPK_ROCK_ROCK2_ST	Q92673	SORL1	O75116	ROCK2	S2206	S2206L	2206	Missense	central	0	yes	31.665	0.000	PhosphoSitePlus	TCGA;COSMIC	20.789	Loss
AGC_DMPK_ROCK_ROCK2_ST	Q92673	SORL1	O75116	ROCK2	S2206	M2201I	2201	Missense	distal	-5	no	31.665	28.256	PhosphoSitePlus	TCGA;COSMIC	20.789	Down-regulation
AGC_DMPK_ROCK_ROCK2_ST	Q92673	SORL1	O75116	ROCK2	S2206	M2211I	2211	Missense	distal	5	no	31.665	31.859	PhosphoSitePlus	TCGA;COSMIC	20.789	Up-regulation
AGC_DMPK_ROCK_ROCK2_ST	Q92673	SORL1	O75116	ROCK2	S2206	G2204R	2204	Missense	proximal	-2	no	31.665	39.257	PhosphoSitePlus	TCGA;COSMIC	20.789	Up-regulation
AGC_DMPK_ROCK_ROCK2_ST	Q16555	DPYSL2	O75116	ROCK2	T13	R16H	16	Missense	distal	3	no	50.561	52.345	EPSD	TCGA;ICGC;COSMIC	20.789	Up-regulation
AGC_DMPK_ROCK_ROCK2_ST	Q16555	DPYSL2	O75116	ROCK2	S14	R16H	16	Missense	proximal	2	no	37.529	37.798	EPSD	TCGA;ICGC;COSMIC	20.789	Up-regulation
AGC_DMPK_ROCK_ROCK2_ST	Q16555	DPYSL2	O75116	ROCK2	S85	P79S	79	Missense	distal	-6	no	27.245	27.606	EPSD	TCGA	20.789	Up-regulation
AGC_DMPK_ROCK_ROCK2_ST	Q16555	DPYSL2	O75116	ROCK2	S85	Q91R	91	Missense	distal	6	no	27.245	26.656	EPSD	TCGA;COSMIC	20.789	Down-regulation
AGC_DMPK_ROCK_ROCK2_ST	Q16555	DPYSL2	O75116	ROCK2	T555	P561S	561	Missense	distal	6	no	39.349	38.875	PhosphoSitePlus	TCGA;COSMIC	20.789	Down-regulation
AGC_DMPK_ROCK_ROCK2_ST	Q16555	DPYSL2	O75116	ROCK2	T555	R553H	553	Missense	proximal	-2	no	39.349	30.575	PhosphoSitePlus	TCGA;COSMIC	20.789	Down-regulation
AGC_DMPK_ROCK_ROCK2_ST	P10916	MYL2	O75116	ROCK2	S15	F18L	18	Missense	distal	3	no	37.571	38.499	PhosphoSitePlus	TCGA;ICGC	20.789	Up-regulation
AGC_DMPK_ROCK_ROCK2_ST	P10916	MYL2	O75116	ROCK2	S15	G11V	11	Missense	distal	-4	no	37.571	37.721	PhosphoSitePlus	TCGA;ICGC;COSMIC	20.789	Up-regulation
AGC_DMPK_ROCK_ROCK2_ST	P10916	MYL2	O75116	ROCK2	S15	G12V	12	Missense	distal	-3	no	37.571	17.298	PhosphoSitePlus	TCGA;ICGC;COSMIC	20.789	Loss
AGC_DMPK_ROCK_ROCK2_ST	P10916	MYL2	O75116	ROCK2	S15	A13T	13	Missense	proximal	-2	no	37.571	38.125	PhosphoSitePlus	TCGA;ICGC;COSMIC	20.789	Up-regulation
AGC_DMPK_ROCK_ROCK2_ST	P10916	MYL2	O75116	ROCK2	S15	F18V	18	Missense	distal	3	no	37.571	37.446	PhosphoSitePlus	TCGA;ICGC;COSMIC	20.789	Down-regulation
AGC_DMPK_ROCK_ROCK2_ST	P10916	MYL2	O75116	ROCK2	S15	E22K	22	Missense	distal	7	no	37.571	37.480	PhosphoSitePlus	TCGA;ICGC;COSMIC	20.789	Down-regulation
AGC_DMPK_ROCK_ROCK2_ST	P10916	MYL2	O75116	ROCK2	T124	A127V	127	Missense	distal	3	no	23.427	22.310	EPSD	TCGA;COSMIC	20.789	Down-regulation
AGC_DMPK_ROCK_ROCK2_ST	P10916	MYL2	O75116	ROCK2	T124	S131F	131	Missense	distal	7	no	23.427	25.819	EPSD	TCGA;COSMIC	20.789	Up-regulation
AGC_DMPK_ROCK_ROCK2_ST	P10916	MYL2	O75116	ROCK2	T124	V119I	119	Missense	distal	-5	no	23.427	25.732	EPSD	TCGA;COSMIC	20.789	Up-regulation
AGC_DMPK_ROCK_ROCK2_ST	Q96A00	PPP1R14A	O75116	ROCK2	T38	R36C	36	Missense	proximal	-2	no	34.400	10.996	PhosphoSitePlus	TCGA;ICGC;COSMIC	20.789	Loss
AGC_DMPK_ROCK_ROCK2_ST	Q96A00	PPP1R14A	O75116	ROCK2	T38	R44W	44	Missense	distal	6	no	34.400	34.736	PhosphoSitePlus	TCGA;ICGC;COSMIC	20.789	Up-regulation
AGC_DMPK_ROCK_ROCK2_ST	Q96A00	PPP1R14A	O75116	ROCK2	S128	P129T	129	Missense	proximal	1	no	30.294	30.324	EPSD	TCGA;COSMIC	20.789	Up-regulation
AGC_DMPK_ROCK_ROCK2_ST	Q96A00	PPP1R14A	O75116	ROCK2	S130	P129T	129	Missense	proximal	-1	no	26.835	26.668	EPSD	TCGA;COSMIC	20.789	Down-regulation
AGC_DMPK_ROCK_ROCK2_ST	Q96A00	PPP1R14A	O75116	ROCK2	S136	L138P	138	Missense	proximal	2	no	32.346	32.122	EPSD	TCGA;ICGC	20.789	Down-regulation
AGC_DMPK_ROCK_ROCK2_ST	Q96A00	PPP1R14A	O75116	ROCK2	S136	P129T	129	Missense	distal	-7	no	32.346	32.220	EPSD	TCGA;COSMIC	20.789	Down-regulation
AGC_DMPK_ROCK_ROCK2_ST	O75116	ROCK2	O75116	ROCK2	T7	P5S	5	Missense	proximal	-2	no	31.941	31.972	EPSD	TCGA;ICGC;COSMIC	20.789	Up-regulation
AGC_DMPK_ROCK_ROCK2_ST	O75116	ROCK2	O75116	ROCK2	T16	A17S	17	Missense	proximal	1	no	23.398	23.359	EPSD	TCGA;ICGC;COSMIC	20.789	Down-regulation
AGC_DMPK_ROCK_ROCK2_ST	O75116	ROCK2	O75116	ROCK2	T16	E15K	15	Missense	proximal	-1	no	23.398	23.743	EPSD	TCGA;ICGC;COSMIC	20.789	Up-regulation
AGC_DMPK_ROCK_ROCK2_ST	O75116	ROCK2	O75116	ROCK2	T1212	Q1213L	1213	Missense	proximal	1	no	23.226	23.326	EPSD	TCGA;ICGC;COSMIC	20.789	Up-regulation
AGC_DMPK_ROCK_ROCK2_ST	O75116	ROCK2	O75116	ROCK2	T1212	H1207Y	1207	Missense	distal	-5	no	23.226	20.528	EPSD	TCGA	20.789	Loss
AGC_DMPK_ROCK_ROCK2_ST	O75116	ROCK2	O75116	ROCK2	S1379	S1379N	1379	Missense	central	0	yes	39.468	0.000	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	20.789	Loss
AGC_DMPK_ROCK_ROCK2_ST	P98082	DAB2	O75116	ROCK2	S24	K21E	21	Missense	distal	-3	no	22.148	13.769	EPSD	TCGA;ICGC;COSMIC	20.789	Loss
AGC_DMPK_ROCK_ROCK2_ST	P98082	DAB2	O75116	ROCK2	S24	A18G	18	Missense	distal	-6	no	22.148	24.896	EPSD	TCGA;ICGC;COSMIC	20.789	Up-regulation
AGC_DMPK_ROCK_ROCK2_ST	P98082	DAB2	O75116	ROCK2	S24	A22T	22	Missense	proximal	-2	no	22.148	22.701	EPSD	TCGA;ICGC;COSMIC	20.789	Up-regulation
AGC_DMPK_ROCK_ROCK2_ST	P98082	DAB2	O75116	ROCK2	S24	A18V	18	Missense	distal	-6	no	22.148	18.953	EPSD	TCGA;ICGC;COSMIC	20.789	Loss
AGC_DMPK_ROCK_ROCK2_ST	P98082	DAB2	O75116	ROCK2	S24	K29N	29	Missense	distal	5	no	22.148	22.615	EPSD	TCGA;ICGC;COSMIC	20.789	Up-regulation
AGC_DMPK_ROCK_ROCK2_ST	P98082	DAB2	O75116	ROCK2	T674	E672K	672	Missense	proximal	-2	no	18.886	23.457	EPSD	TCGA;COSMIC	20.789	Gain
AGC_DMPK_ROCK_ROCK2_ST	P98082	DAB2	O75116	ROCK2	T678	E672K	672	Missense	distal	-6	no	16.283	21.744	EPSD	TCGA;COSMIC	20.789	Gain
AGC_DMPK_ROCK_ROCK2_ST	P98082	DAB2	O75116	ROCK2	S680	A683V	683	Missense	distal	3	no	22.187	21.070	EPSD	TCGA;COSMIC	20.789	Down-regulation
AGC_DMPK_ROCK_ROCK2_ST	P98082	DAB2	O75116	ROCK2	S723	P725R	725	Missense	proximal	2	no	30.116	30.031	PhosphoSitePlus	TCGA;COSMIC	20.789	Down-regulation
AGC_DMPK_ROCK_ROCK2_ST	P98082	DAB2	O75116	ROCK2	S723	S723F	723	Missense	central	0	yes	30.116	0.000	PhosphoSitePlus	TCGA;COSMIC;CCLE	20.789	Loss
AGC_DMPK_ROCK_ROCK2_ST	P98082	DAB2	O75116	ROCK2	S723	S723P	723	Missense	central	0	yes	30.116	0.000	PhosphoSitePlus	TCGA;COSMIC	20.789	Loss
AGC_DMPK_ROCK_ROCK2_ST	Q99962	SH3GL2	O75116	ROCK2	T14	K20R	20	Missense	distal	6	no	41.153	41.134	PhosphoSitePlus	TCGA;ICGC;COSMIC	20.789	Down-regulation
AGC_DMPK_ROCK_ROCK2_ST	Q99962	SH3GL2	O75116	ROCK2	S262	R260Q	260	Missense	proximal	-2	no	23.343	14.502	EPSD	TCGA;ICGC;COSMIC	20.789	Loss
AGC_DMPK_ROCK_ROCK2_ST	Q99962	SH3GL2	O75116	ROCK2	S262	P266S	266	Missense	distal	4	no	23.343	22.525	EPSD	TCGA;ICGC;COSMIC	20.789	Down-regulation
AGC_DMPK_ROCK_ROCK2_ST	Q99962	SH3GL2	O75116	ROCK2	S262	P266L	266	Missense	distal	4	no	23.343	22.863	EPSD	TCGA;ICGC;COSMIC	20.789	Down-regulation
AGC_DMPK_ROCK_ROCK2_ST	Q99962	SH3GL2	O75116	ROCK2	S262	E264V	264	Missense	proximal	2	no	23.343	23.280	EPSD	TCGA;ICGC;COSMIC	20.789	Down-regulation
AGC_DMPK_ROCK_ROCK2_ST	P05067	APP	O75116	ROCK2	S271	A273T	273	Missense	proximal	2	no	27.612	27.431	EPSD	TCGA	20.789	Down-regulation
AGC_DMPK_ROCK_ROCK2_ST	P05067	APP	O75116	ROCK2	S271	T274A	274	Missense	distal	3	no	27.612	28.985	EPSD	TCGA;COSMIC;CCLE	20.789	Up-regulation
AGC_DMPK_ROCK_ROCK2_ST	P05067	APP	O75116	ROCK2	T276	A273T	273	Missense	distal	-3	no	22.158	24.333	EPSD	TCGA	20.789	Up-regulation
AGC_DMPK_ROCK_ROCK2_ST	P05067	APP	O75116	ROCK2	T276	T274A	274	Missense	proximal	-2	no	22.158	21.604	EPSD	TCGA;COSMIC;CCLE	20.789	Down-regulation
AGC_DMPK_ROCK_ROCK2_ST	P05067	APP	O75116	ROCK2	S348	K351R	351	Missense	distal	3	no	21.197	19.011	EPSD	TCGA;COSMIC	20.789	Loss
AGC_DMPK_ROCK_ROCK2_ST	P05067	APP	O75116	ROCK2	S679	H685R	685	Missense	distal	6	no	23.926	23.513	EPSD	TCGA;COSMIC	20.789	Down-regulation
AGC_DMPK_ROCK_ROCK2_ST	P05067	APP	O75116	ROCK2	T729	Q727L	727	Missense	proximal	-2	no	32.174	26.755	EPSD	TCGA;COSMIC	20.789	Down-regulation
AGC_DMPK_ROCK_ROCK2_ST	P05067	APP	O75116	ROCK2	T729	T729A	729	Missense	central	0	yes	32.174	0.000	EPSD	TCGA;COSMIC	20.789	Loss
AGC_DMPK_ROCK_ROCK2_ST	P05067	APP	O75116	ROCK2	T729	S730F	730	Missense	proximal	1	no	32.174	32.135	EPSD	TCGA	20.789	Down-regulation
AGC_DMPK_ROCK_ROCK2_ST	P05067	APP	O75116	ROCK2	S730	Q727L	727	Missense	distal	-3	no	28.131	19.220	EPSD	TCGA;COSMIC	20.789	Loss
AGC_DMPK_ROCK_ROCK2_ST	P05067	APP	O75116	ROCK2	S730	T729A	729	Missense	proximal	-1	no	28.131	28.696	EPSD	TCGA;COSMIC	20.789	Up-regulation
AGC_DMPK_ROCK_ROCK2_ST	P05067	APP	O75116	ROCK2	S730	S730F	730	Missense	central	0	yes	28.131	0.000	EPSD	TCGA	20.789	Loss
AGC_DMPK_ROCK_ROCK2_ST	Q15417	CNN3	O75116	ROCK2	S13	K17N	17	Missense	distal	4	no	22.017	22.350	EPSD	TCGA;ICGC;COSMIC;CCLE	20.789	Up-regulation
AGC_DMPK_ROCK_ROCK2_ST	Q15417	CNN3	O75116	ROCK2	T170	Q167R	167	Missense	distal	-3	no	27.004	37.723	EPSD	TCGA;ICGC;COSMIC	20.789	Up-regulation
AGC_DMPK_ROCK_ROCK2_ST	Q15417	CNN3	O75116	ROCK2	T184	P191L	191	Missense	distal	7	no	29.220	29.444	EPSD	TCGA;ICGC;COSMIC	20.789	Up-regulation
AGC_DMPK_ROCK_ROCK2_ST	Q15417	CNN3	O75116	ROCK2	T210	M208I	208	Missense	proximal	-2	no	25.163	11.902	EPSD	TCGA;ICGC;COSMIC	20.789	Loss
AGC_DMPK_ROCK_ROCK2_ST	Q15417	CNN3	O75116	ROCK2	S215	M208I	208	Missense	distal	-7	no	29.866	29.775	EPSD	TCGA;ICGC;COSMIC	20.789	Down-regulation
AGC_DMPK_ROCK_ROCK2_ST	Q15417	CNN3	O75116	ROCK2	T234	S241L	241	Missense	distal	7	no	22.720	24.209	EPSD	TCGA;ICGC;COSMIC	20.789	Up-regulation
AGC_DMPK_ROCK_ROCK2_ST	Q15417	CNN3	O75116	ROCK2	T249	S244F	244	Missense	distal	-5	no	26.503	26.451	EPSD	TCGA;ICGC;COSMIC	20.789	Down-regulation
AGC_DMPK_ROCK_ROCK2_ST	Q15417	CNN3	O75116	ROCK2	S259	M258V	258	Missense	proximal	-1	no	23.547	23.520	EPSD	TCGA;ICGC;COSMIC	20.789	Down-regulation
AGC_DMPK_ROCK_ROCK2_ST	Q15417	CNN3	O75116	ROCK2	S259	M258I	258	Missense	proximal	-1	no	23.547	23.855	EPSD	TCGA;ICGC;COSMIC	20.789	Up-regulation
AGC_DMPK_ROCK_ROCK2_ST	Q15417	CNN3	O75116	ROCK2	S259	R265W	265	Missense	distal	6	no	23.547	23.883	EPSD	TCGA;ICGC;COSMIC	20.789	Up-regulation
AGC_DMPK_ROCK_ROCK2_ST	Q15417	CNN3	O75116	ROCK2	T288	N283S	283	Missense	distal	-5	no	29.655	28.536	EPSD	TCGA;ICGC	20.789	Down-regulation
AGC_DMPK_ROCK_ROCK2_ST	Q15417	CNN3	O75116	ROCK2	S323	D324N	324	Missense	proximal	1	no	23.116	23.208	EPSD	TCGA;ICGC;COSMIC	20.789	Up-regulation
AGC_DMPK_ROCK_ROCK2_ST	Q96C90	PPP1R14B	O75116	ROCK2	T57	V50L	50	Missense	distal	-7	no	31.042	31.164	PhosphoSitePlus	TCGA;ICGC;COSMIC	20.789	Up-regulation
AGC_DMPK_ROCK_ROCK2_ST	Q96C90	PPP1R14B	O75116	ROCK2	S142	Q145H	145	Missense	distal	3	no	30.324	31.244	EPSD	TCGA;COSMIC	20.789	Up-regulation
AGC_DMPK_ROCK_ROCK2_ST	Q96C90	PPP1R14B	O75116	ROCK2	T143	Q145H	145	Missense	proximal	2	no	24.071	24.351	EPSD	TCGA;COSMIC	20.789	Up-regulation
AGC_DMPK_ROCK_ROCK2_ST	P68104	EEF1A1	O75116	ROCK2	T6	H7R	7	Missense	proximal	1	no	30.320	30.223	EPSD	TCGA;ICGC;COSMIC	20.789	Down-regulation
AGC_DMPK_ROCK_ROCK2_ST	P68104	EEF1A1	O75116	ROCK2	T6	V12I	12	Missense	distal	6	no	30.320	30.525	EPSD	TCGA;ICGC;COSMIC	20.789	Up-regulation
AGC_DMPK_ROCK_ROCK2_ST	P68104	EEF1A1	O75116	ROCK2	T6	I10V	10	Missense	distal	4	no	30.320	29.737	EPSD	TCGA;ICGC;COSMIC	20.789	Down-regulation
AGC_DMPK_ROCK_ROCK2_ST	P68104	EEF1A1	O75116	ROCK2	T6	K5N	5	Missense	proximal	-1	no	30.320	30.595	EPSD	TCGA;ICGC;COSMIC	20.789	Up-regulation
AGC_DMPK_ROCK_ROCK2_ST	P68104	EEF1A1	O75116	ROCK2	S21	L27V	27	Missense	distal	6	no	24.313	24.573	EPSD	TCGA;ICGC;COSMIC	20.789	Up-regulation
AGC_DMPK_ROCK_ROCK2_ST	P68104	EEF1A1	O75116	ROCK2	S21	D17N	17	Missense	distal	-4	no	24.313	21.387	EPSD	TCGA;ICGC;COSMIC	20.789	Down-regulation
AGC_DMPK_ROCK_ROCK2_ST	P68104	EEF1A1	O75116	ROCK2	S21	I28V	28	Missense	distal	7	no	24.313	23.044	EPSD	TCGA;ICGC;COSMIC	20.789	Down-regulation
AGC_DMPK_ROCK_ROCK2_ST	P68104	EEF1A1	O75116	ROCK2	T22	L27V	27	Missense	distal	5	no	20.963	21.968	EPSD	TCGA;ICGC;COSMIC	20.789	Up-regulation
AGC_DMPK_ROCK_ROCK2_ST	P68104	EEF1A1	O75116	ROCK2	T22	Y29C	29	Missense	distal	7	no	20.963	21.633	EPSD	TCGA;ICGC;COSMIC	20.789	Up-regulation
AGC_DMPK_ROCK_ROCK2_ST	P68104	EEF1A1	O75116	ROCK2	T22	D17N	17	Missense	distal	-5	no	20.963	23.723	EPSD	TCGA;ICGC;COSMIC	20.789	Up-regulation
AGC_DMPK_ROCK_ROCK2_ST	P68104	EEF1A1	O75116	ROCK2	T22	I28V	28	Missense	distal	6	no	20.963	20.758	EPSD	TCGA;ICGC;COSMIC	20.789	Loss
AGC_DMPK_ROCK_ROCK2_ST	P68104	EEF1A1	O75116	ROCK2	T23	D17N	17	Missense	distal	-6	no	20.171	22.368	EPSD	TCGA;ICGC;COSMIC	20.789	Gain
AGC_DMPK_ROCK_ROCK2_ST	P68104	EEF1A1	O75116	ROCK2	T24	L27V	27	Missense	distal	3	no	22.142	21.089	EPSD	TCGA;ICGC;COSMIC	20.789	Down-regulation
AGC_DMPK_ROCK_ROCK2_ST	P68104	EEF1A1	O75116	ROCK2	T24	Y29C	29	Missense	distal	5	no	22.142	22.939	EPSD	TCGA;ICGC;COSMIC	20.789	Up-regulation
AGC_DMPK_ROCK_ROCK2_ST	P68104	EEF1A1	O75116	ROCK2	T24	D17N	17	Missense	distal	-7	no	22.142	21.604	EPSD	TCGA;ICGC;COSMIC	20.789	Down-regulation
AGC_DMPK_ROCK_ROCK2_ST	P68104	EEF1A1	O75116	ROCK2	T24	I28V	28	Missense	distal	4	no	22.142	21.558	EPSD	TCGA;ICGC;COSMIC	20.789	Down-regulation
AGC_DMPK_ROCK_ROCK2_ST	P68104	EEF1A1	O75116	ROCK2	S53	G50R	50	Missense	distal	-3	no	25.807	33.992	EPSD	TCGA;ICGC;COSMIC	20.789	Up-regulation
AGC_DMPK_ROCK_ROCK2_ST	P68104	EEF1A1	O75116	ROCK2	S53	A46T	46	Missense	distal	-7	no	25.807	26.105	EPSD	TCGA;ICGC;COSMIC	20.789	Up-regulation
AGC_DMPK_ROCK_ROCK2_ST	P68104	EEF1A1	O75116	ROCK2	S53	A46D	46	Missense	distal	-7	no	25.807	26.715	EPSD	TCGA;ICGC	20.789	Up-regulation
AGC_DMPK_ROCK_ROCK2_ST	P68104	EEF1A1	O75116	ROCK2	S163	Y167D	167	Missense	distal	4	no	26.427	26.570	EPSD	TCGA;ICGC;COSMIC	20.789	Up-regulation
AGC_DMPK_ROCK_ROCK2_ST	P68104	EEF1A1	O75116	ROCK2	S163	Y167C	167	Missense	distal	4	no	26.427	26.514	EPSD	TCGA;ICGC;COSMIC	20.789	Up-regulation
AGC_DMPK_ROCK_ROCK2_ST	P68104	EEF1A1	O75116	ROCK2	T227	S224G	224	Missense	distal	-3	no	18.640	24.360	EPSD	TCGA;ICGC;COSMIC	20.789	Gain
AGC_DMPK_ROCK_ROCK2_ST	P68104	EEF1A1	O75116	ROCK2	T279	V277G	277	Missense	proximal	-2	no	9.825	26.297	EPSD	TCGA;ICGC;COSMIC	20.789	Gain
AGC_DMPK_ROCK_ROCK2_ST	P68104	EEF1A1	O75116	ROCK2	S383	D380H	380	Missense	distal	-3	no	27.210	30.362	EPSD	TCGA;ICGC;COSMIC	20.789	Up-regulation
AGC_DMPK_ROCK_ROCK2_ST	P68104	EEF1A1	O75116	ROCK2	S383	E377D	377	Missense	distal	-6	no	27.210	28.600	EPSD	TCGA;ICGC;COSMIC	20.789	Up-regulation
AGC_DMPK_ROCK_ROCK2_ST	P68104	EEF1A1	O75116	ROCK2	T432	Q431E	431	Missense	proximal	-1	no	35.861	35.542	PhosphoSitePlus	TCGA;ICGC;COSMIC	20.789	Down-regulation
AGC_DMPK_ROCK_ROCK2_ST	P68104	EEF1A1	O75116	ROCK2	T432	R430T	430	Missense	proximal	-2	no	35.861	23.431	PhosphoSitePlus	TCGA;ICGC;COSMIC	20.789	Down-regulation
AGC_DMPK_ROCK_ROCK2_ST	P68104	EEF1A1	O75116	ROCK2	T432	V433F	433	Missense	proximal	1	no	35.861	35.845	PhosphoSitePlus	TCGA;ICGC;COSMIC	20.789	Down-regulation
AGC_DMPK_ROCK_ROCK2_ST	P68104	EEF1A1	O75116	ROCK2	T432	T432I	432	Missense	central	0	yes	35.861	0.000	PhosphoSitePlus	TCGA;ICGC;COSMIC	20.789	Loss
AGC_DMPK_ROCK_ROCK2_ST	P68104	EEF1A1	O75116	ROCK2	T432	M429V	429	Missense	distal	-3	no	35.861	13.829	PhosphoSitePlus	TCGA;ICGC;COSMIC	20.789	Loss
AGC_DMPK_ROCK_ROCK2_ST	P68104	EEF1A1	O75116	ROCK2	T432	A434T	434	Missense	proximal	2	no	35.861	35.679	PhosphoSitePlus	TCGA;ICGC;COSMIC	20.789	Down-regulation
AGC_DMPK_ROCK_ROCK2_ST	P68104	EEF1A1	O75116	ROCK2	T432	R427C	427	Missense	distal	-5	no	35.861	29.776	PhosphoSitePlus	TCGA;ICGC;COSMIC	20.789	Down-regulation
AGC_DMPK_ROCK_ROCK2_ST	P68104	EEF1A1	O75116	ROCK2	T432	A434V	434	Missense	proximal	2	no	35.861	35.474	PhosphoSitePlus	TCGA;COSMIC	20.789	Down-regulation
AGC_DMPK_ROCK_ROCK2_ST	P68104	EEF1A1	O75116	ROCK2	T452	V451D	451	Missense	proximal	-1	no	37.573	36.751	EPSD	TCGA;ICGC;COSMIC	20.789	Down-regulation
AGC_DMPK_ROCK_ROCK2_ST	P68104	EEF1A1	O75116	ROCK2	T452	Q459H	459	Missense	distal	7	no	37.573	37.068	EPSD	TCGA;ICGC;COSMIC	20.789	Down-regulation
AGC_DMPK_ROCK_ROCK2_ST	P68104	EEF1A1	O75116	ROCK2	T452	T452N	452	Missense	central	0	yes	37.573	0.000	EPSD	TCGA;ICGC;COSMIC	20.789	Loss
AGC_DMPK_ROCK_ROCK2_ST	O14974	PPP1R12A	O75116	ROCK2	S20	E25K	25	Missense	distal	5	no	26.636	25.210	EPSD	TCGA;ICGC;COSMIC	20.789	Down-regulation
AGC_DMPK_ROCK_ROCK2_ST	O14974	PPP1R12A	O75116	ROCK2	S20	E21D	21	Missense	proximal	1	no	26.636	26.594	EPSD	TCGA;ICGC;COSMIC	20.789	Down-regulation
AGC_DMPK_ROCK_ROCK2_ST	O14974	PPP1R12A	O75116	ROCK2	T22	E25K	25	Missense	distal	3	no	28.098	29.357	EPSD	TCGA;ICGC;COSMIC	20.789	Up-regulation
AGC_DMPK_ROCK_ROCK2_ST	O14974	PPP1R12A	O75116	ROCK2	T22	E21D	21	Missense	proximal	-1	no	28.098	27.360	EPSD	TCGA;ICGC;COSMIC	20.789	Down-regulation
AGC_DMPK_ROCK_ROCK2_ST	O14974	PPP1R12A	O75116	ROCK2	S445	T443M	443	Missense	proximal	-2	no	12.881	22.556	EPSD	TCGA;ICGC;COSMIC	20.789	Gain
AGC_DMPK_ROCK_ROCK2_ST	O14974	PPP1R12A	O75116	ROCK2	S472	R475K	475	Missense	distal	3	no	18.606	20.792	EPSD	TCGA;ICGC;COSMIC	20.789	Gain
AGC_DMPK_ROCK_ROCK2_ST	O14974	PPP1R12A	O75116	ROCK2	S477	R475K	475	Missense	proximal	-2	no	22.795	13.842	EPSD	TCGA;ICGC;COSMIC	20.789	Loss
AGC_DMPK_ROCK_ROCK2_ST	O14974	PPP1R12A	O75116	ROCK2	S478	R475K	475	Missense	distal	-3	no	24.684	16.696	EPSD	TCGA;ICGC;COSMIC	20.789	Loss
AGC_DMPK_ROCK_ROCK2_ST	O14974	PPP1R12A	O75116	ROCK2	S668	R667I	667	Missense	proximal	-1	no	21.836	21.562	EPSD	TCGA;ICGC;COSMIC	20.789	Down-regulation
AGC_DMPK_ROCK_ROCK2_ST	O14974	PPP1R12A	O75116	ROCK2	T696	R694T	694	Missense	proximal	-2	no	40.321	27.891	PhosphoSitePlus	TCGA;COSMIC	20.789	Down-regulation
AGC_DMPK_ROCK_ROCK2_ST	O14974	PPP1R12A	O75116	ROCK2	T696	T700S	700	Missense	distal	4	no	40.321	39.542	PhosphoSitePlus	TCGA;ICGC;COSMIC	20.789	Down-regulation
AGC_DMPK_ROCK_ROCK2_ST	O14974	PPP1R12A	O75116	ROCK2	S790	S789R	789	Missense	proximal	-1	no	22.316	22.611	EPSD	TCGA;ICGC;COSMIC	20.789	Up-regulation
AGC_DMPK_ROCK_ROCK2_ST	O14974	PPP1R12A	O75116	ROCK2	S852	R851K	851	Missense	proximal	-1	no	31.029	30.680	EPSD	TCGA;ICGC;COSMIC	20.789	Down-regulation
AGC_DMPK_ROCK_ROCK2_ST	O14974	PPP1R12A	O75116	ROCK2	S852	T853A	853	Missense	proximal	1	no	31.029	31.086	EPSD	TCGA;ICGC;COSMIC	20.789	Up-regulation
AGC_DMPK_ROCK_ROCK2_ST	O14974	PPP1R12A	O75116	ROCK2	S852	S852Y	852	Missense	central	0	yes	31.029	0.000	EPSD	TCGA;ICGC	20.789	Loss
AGC_DMPK_ROCK_ROCK2_ST	O14974	PPP1R12A	O75116	ROCK2	T853	R851K	851	Missense	proximal	-2	no	31.689	22.736	EPSD	TCGA;ICGC;COSMIC	20.789	Down-regulation
AGC_DMPK_ROCK_ROCK2_ST	O14974	PPP1R12A	O75116	ROCK2	T853	T853A	853	Missense	central	0	yes	31.689	0.000	EPSD	TCGA;ICGC;COSMIC	20.789	Loss
AGC_DMPK_ROCK_ROCK2_ST	O14974	PPP1R12A	O75116	ROCK2	T853	S852Y	852	Missense	proximal	-1	no	31.689	31.046	EPSD	TCGA;ICGC	20.789	Down-regulation
AGC_DMPK_ROCK_ROCK2_ST	O14974	PPP1R12A	O75116	ROCK2	S856	R851K	851	Missense	distal	-5	no	21.083	20.683	EPSD	TCGA;ICGC;COSMIC	20.789	Loss
AGC_DMPK_ROCK_ROCK2_ST	O14974	PPP1R12A	O75116	ROCK2	S856	T853A	853	Missense	distal	-3	no	21.083	18.907	EPSD	TCGA;ICGC;COSMIC	20.789	Loss
AGC_DMPK_ROCK_ROCK2_ST	O14974	PPP1R12A	O75116	ROCK2	S856	S852Y	852	Missense	distal	-4	no	21.083	23.918	EPSD	TCGA;ICGC	20.789	Up-regulation
AGC_DMPK_ROCK_ROCK2_ST	O14974	PPP1R12A	O75116	ROCK2	T892	E891K	891	Missense	proximal	-1	no	31.348	31.693	EPSD	TCGA;ICGC;COSMIC	20.789	Up-regulation
AGC_DMPK_ROCK_ROCK2_ST	O14974	PPP1R12A	O75116	ROCK2	T892	S894Y	894	Missense	proximal	2	no	31.348	31.117	EPSD	TCGA;COSMIC	20.789	Down-regulation
STE_STE-Unique_MAP3K14_ST	P25963	NFKBIA	Q99558	MAP3K14	S32	D31N	31	Missense	proximal	-1	no	360.434	344.407	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	201.043	Down-regulation
STE_STE-Unique_MAP3K14_ST	P25963	NFKBIA	Q99558	MAP3K14	S32	D27H	27	Missense	distal	-5	no	360.434	332.783	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	201.043	Down-regulation
STE_STE-Unique_MAP3K14_ST	P25963	NFKBIA	Q99558	MAP3K14	S36	E41K	41	Missense	distal	5	no	397.236	397.485	PhosphoSitePlus;EPSD	TCGA;ICGC	201.043	Up-regulation
STE_STE-Unique_MAP3K14_ST	P25963	NFKBIA	Q99558	MAP3K14	S36	D31N	31	Missense	distal	-5	no	397.236	374.345	PhosphoSitePlus;EPSD	TCGA;ICGC;COSMIC	201.043	Down-regulation
STE_STE-Unique_MAP3K14_ST	P25963	NFKBIA	Q99558	MAP3K14	S36	Y42C	42	Missense	distal	6	no	397.236	389.115	PhosphoSitePlus;EPSD	TCGA;ICGC;COSMIC	201.043	Down-regulation
STE_STE-Unique_MAP3K14_ST	P25963	NFKBIA	Q99558	MAP3K14	T291	D290G	290	Missense	proximal	-1	no	221.515	223.153	EPSD	TCGA	201.043	Up-regulation
STE_STE-Unique_MAP3K14_ST	P25963	NFKBIA	Q99558	MAP3K14	T291	S293T	293	Missense	proximal	2	no	221.515	220.524	EPSD	TCGA;COSMIC	201.043	Down-regulation
STE_STE-Unique_MAP3K14_ST	P25963	NFKBIA	Q99558	MAP3K14	S293	D290G	290	Missense	distal	-3	no	244.510	244.648	EPSD	TCGA	201.043	Up-regulation
STE_STE-Unique_MAP3K14_ST	O15111	CHUK	Q99558	MAP3K14	S123	E118Q	118	Missense	distal	-5	no	241.494	221.748	EPSD	TCGA;ICGC;COSMIC	201.043	Down-regulation
STE_STE-Unique_MAP3K14_ST	O15111	CHUK	Q99558	MAP3K14	S123	S123Y	123	Missense	central	0	yes	241.494	0.000	EPSD	TCGA;ICGC;COSMIC	201.043	Loss
STE_STE-Unique_MAP3K14_ST	O15111	CHUK	Q99558	MAP3K14	S176	D171Y	171	Missense	distal	-5	no	389.213	368.696	PhosphoSitePlus;EPSD	TCGA;ICGC;COSMIC	201.043	Down-regulation
STE_STE-Unique_MAP3K14_ST	O15111	CHUK	Q99558	MAP3K14	S473	L480V	480	Missense	distal	7	no	196.135	201.828	EPSD	TCGA;ICGC;COSMIC	201.043	Gain
STE_STE-Unique_MAP3K14_ST	O14920	IKBKB	Q99558	MAP3K14	S177	G176D	176	Missense	proximal	-1	no	371.956	370.318	PhosphoSitePlus;EPSD	TCGA;COSMIC	201.043	Down-regulation
STE_STE-Unique_MAP3K14_ST	O14920	IKBKB	Q99558	MAP3K14	S177	K171R	171	Missense	distal	-6	no	371.956	354.368	PhosphoSitePlus;EPSD	TCGA;COSMIC	201.043	Down-regulation
STE_STE-Unique_MAP3K14_ST	O14920	IKBKB	Q99558	MAP3K14	S177	V183M	183	Missense	distal	6	no	371.956	362.641	PhosphoSitePlus;EPSD	TCGA;COSMIC	201.043	Down-regulation
STE_STE-Unique_MAP3K14_ST	O14920	IKBKB	Q99558	MAP3K14	S181	G176D	176	Missense	distal	-5	no	370.108	383.507	EPSD;PhosphoSitePlus	TCGA;COSMIC	201.043	Up-regulation
STE_STE-Unique_MAP3K14_ST	O14920	IKBKB	Q99558	MAP3K14	S181	V183M	183	Missense	proximal	2	no	370.108	371.056	EPSD;PhosphoSitePlus	TCGA;COSMIC	201.043	Up-regulation
STE_STE-Unique_MAP3K14_ST	O14920	IKBKB	Q99558	MAP3K14	S239	H232R	232	Missense	distal	-7	no	204.532	209.457	EPSD	TCGA;COSMIC	201.043	Up-regulation
STE_STE-Unique_MAP3K14_ST	O14920	IKBKB	Q99558	MAP3K14	S239	Q237R	237	Missense	proximal	-2	no	204.532	194.567	EPSD	TCGA;COSMIC	201.043	Loss
STE_STE-Unique_MAP3K14_ST	O14920	IKBKB	Q99558	MAP3K14	S256	Y261C	261	Missense	distal	5	no	226.542	226.416	EPSD	TCGA;COSMIC	201.043	Down-regulation
STE_STE-Unique_MAP3K14_ST	O14920	IKBKB	Q99558	MAP3K14	S256	T252M	252	Missense	distal	-4	no	226.542	217.136	EPSD	TCGA;COSMIC	201.043	Down-regulation
STE_STE-Unique_MAP3K14_ST	O14920	IKBKB	Q99558	MAP3K14	S256	G251R	251	Missense	distal	-5	no	226.542	228.075	EPSD	TCGA;COSMIC	201.043	Up-regulation
STE_STE-Unique_MAP3K14_ST	O14920	IKBKB	Q99558	MAP3K14	T368	P363R	363	Missense	distal	-5	no	205.138	222.332	EPSD	TCGA;COSMIC	201.043	Up-regulation
STE_STE-Unique_MAP3K14_ST	O14920	IKBKB	Q99558	MAP3K14	T368	P363L	363	Missense	distal	-5	no	205.138	208.292	EPSD	TCGA;COSMIC	201.043	Up-regulation
STE_STE-Unique_MAP3K14_ST	O14920	IKBKB	Q99558	MAP3K14	S476	S471F	471	Missense	distal	-5	no	216.553	200.359	EPSD	TCGA;COSMIC	201.043	Loss
STE_STE-Unique_MAP3K14_ST	O14920	IKBKB	Q99558	MAP3K14	S476	K482T	482	Missense	distal	6	no	216.553	212.493	EPSD	TCGA;COSMIC	201.043	Down-regulation
STE_STE-Unique_MAP3K14_ST	O14920	IKBKB	Q99558	MAP3K14	S489	F486L	486	Missense	distal	-3	no	229.597	229.522	EPSD	TCGA;COSMIC	201.043	Down-regulation
STE_STE-Unique_MAP3K14_ST	O14920	IKBKB	Q99558	MAP3K14	S489	D484N	484	Missense	distal	-5	no	229.597	206.706	EPSD	TCGA;COSMIC	201.043	Down-regulation
STE_STE-Unique_MAP3K14_ST	O14920	IKBKB	Q99558	MAP3K14	S489	K482T	482	Missense	distal	-7	no	229.597	219.237	EPSD	TCGA;COSMIC	201.043	Down-regulation
STE_STE-Unique_MAP3K14_ST	O14920	IKBKB	Q99558	MAP3K14	S489	S489N	489	Missense	central	0	yes	229.597	0.000	EPSD	TCGA;COSMIC	201.043	Loss
STE_STE-Unique_MAP3K14_ST	O14920	IKBKB	Q99558	MAP3K14	S550	R554Q	554	Missense	distal	4	no	251.826	259.730	EPSD	TCGA;ICGC;COSMIC	201.043	Up-regulation
STE_STE-Unique_MAP3K14_ST	O14920	IKBKB	Q99558	MAP3K14	S550	P551L	551	Missense	proximal	1	no	251.826	264.668	EPSD	TCGA;ICGC;COSMIC	201.043	Up-regulation
STE_STE-Unique_MAP3K14_ST	O14920	IKBKB	Q99558	MAP3K14	T583	D580Y	580	Missense	distal	-3	no	216.886	217.102	EPSD	TCGA;ICGC;COSMIC	201.043	Up-regulation
STE_STE-Unique_MAP3K14_ST	O14920	IKBKB	Q99558	MAP3K14	T583	R582Q	582	Missense	proximal	-1	no	216.886	214.208	EPSD	TCGA;ICGC;COSMIC	201.043	Down-regulation
STE_STE-Unique_MAP3K14_ST	O14920	IKBKB	Q99558	MAP3K14	T583	T583N	583	Missense	central	0	yes	216.886	0.000	EPSD	TCGA;ICGC;COSMIC	201.043	Loss
STE_STE-Unique_MAP3K14_ST	O14920	IKBKB	Q99558	MAP3K14	S587	D580Y	580	Missense	distal	-7	no	249.693	241.843	EPSD	TCGA;ICGC;COSMIC	201.043	Down-regulation
STE_STE-Unique_MAP3K14_ST	O14920	IKBKB	Q99558	MAP3K14	S587	R592Q	592	Missense	distal	5	no	249.693	250.135	EPSD	TCGA;ICGC;COSMIC	201.043	Up-regulation
STE_STE-Unique_MAP3K14_ST	O14920	IKBKB	Q99558	MAP3K14	S587	R582Q	582	Missense	distal	-5	no	249.693	246.351	EPSD	TCGA;ICGC;COSMIC	201.043	Down-regulation
STE_STE-Unique_MAP3K14_ST	O14920	IKBKB	Q99558	MAP3K14	S587	T583N	583	Missense	distal	-4	no	249.693	239.036	EPSD	TCGA;ICGC;COSMIC	201.043	Down-regulation
STE_STE-Unique_MAP3K14_ST	O14920	IKBKB	Q99558	MAP3K14	S692	Q690E	690	Missense	proximal	-2	no	222.696	216.144	EPSD	TCGA;COSMIC	201.043	Down-regulation
STE_STE-Unique_MAP3K14_ST	O14920	IKBKB	Q99558	MAP3K14	S692	S689C	689	Missense	distal	-3	no	222.696	222.693	EPSD	TCGA;COSMIC	201.043	Down-regulation
STE_STE-Unique_MAP3K14_ST	O14920	IKBKB	Q99558	MAP3K14	S692	A694T	694	Missense	proximal	2	no	222.696	219.288	EPSD	TCGA	201.043	Down-regulation
STE_STE-Unique_MAP3K14_ST	Q00653	NFKB2	Q99558	MAP3K14	S161	R160H	160	Missense	proximal	-1	no	236.164	220.467	EPSD	TCGA;ICGC;COSMIC	201.043	Down-regulation
STE_STE-Unique_MAP3K14_ST	Q00653	NFKB2	Q99558	MAP3K14	S161	Q164H	164	Missense	distal	3	no	236.164	232.276	EPSD	TCGA;ICGC;COSMIC	201.043	Down-regulation
STE_STE-Unique_MAP3K14_ST	Q00653	NFKB2	Q99558	MAP3K14	S161	L154P	154	Missense	distal	-7	no	236.164	226.897	EPSD	TCGA;ICGC;COSMIC	201.043	Down-regulation
STE_STE-Unique_MAP3K14_ST	Q00653	NFKB2	Q99558	MAP3K14	T167	R160H	160	Missense	distal	-7	no	208.081	203.155	EPSD	TCGA;ICGC;COSMIC	201.043	Down-regulation
STE_STE-Unique_MAP3K14_ST	Q00653	NFKB2	Q99558	MAP3K14	T167	Q164H	164	Missense	distal	-3	no	208.081	208.152	EPSD	TCGA;ICGC;COSMIC	201.043	Up-regulation
STE_STE-Unique_MAP3K14_ST	Q00653	NFKB2	Q99558	MAP3K14	S239	G243E	243	Missense	distal	4	no	184.441	201.188	EPSD	TCGA;ICGC;COSMIC	201.043	Gain
STE_STE-Unique_MAP3K14_ST	Q00653	NFKB2	Q99558	MAP3K14	T740	D735N	735	Missense	distal	-5	no	226.537	203.646	EPSD	TCGA;ICGC;COSMIC	201.043	Down-regulation
STE_STE-Unique_MAP3K14_ST	Q00653	NFKB2	Q99558	MAP3K14	T740	K743N	743	Missense	distal	3	no	226.537	225.405	EPSD	TCGA;ICGC;COSMIC	201.043	Down-regulation
STE_STE-Unique_MAP3K14_ST	Q00653	NFKB2	Q99558	MAP3K14	T811	G815D	815	Missense	distal	4	no	226.871	239.375	EPSD	TCGA;ICGC;COSMIC	201.043	Up-regulation
AGC_RSK_RSKp70_RPS6KB1_ST	Q9BYV9	BACH2	P23443	RPS6KB1	T406	V402M	402	Missense	distal	-4	no	23.964	25.984	EPSD	TCGA;ICGC;COSMIC	24.279	Gain
AGC_RSK_RSKp70_RPS6KB1_ST	Q9BYV9	BACH2	P23443	RPS6KB1	S409	L411I	411	Missense	proximal	2	no	24.580	22.515	EPSD	TCGA;ICGC;COSMIC	24.279	Loss
AGC_RSK_RSKp70_RPS6KB1_ST	Q9BYV9	BACH2	P23443	RPS6KB1	S409	V402M	402	Missense	distal	-7	no	24.580	24.273	EPSD	TCGA;ICGC;COSMIC	24.279	Loss
AGC_RSK_RSKp70_RPS6KB1_ST	Q9BYV9	BACH2	P23443	RPS6KB1	S521	T515A	515	Missense	distal	-6	no	40.367	40.384	PhosphoSitePlus	TCGA;ICGC;COSMIC	24.279	Up-regulation
AGC_RSK_RSKp70_RPS6KB1_ST	Q9BYV9	BACH2	P23443	RPS6KB1	S521	S525T	525	Missense	distal	4	no	40.367	39.617	PhosphoSitePlus	TCGA;ICGC;COSMIC	24.279	Down-regulation
AGC_RSK_RSKp70_RPS6KB1_ST	Q9BYV9	BACH2	P23443	RPS6KB1	S521	T515I	515	Missense	distal	-6	no	40.367	40.408	PhosphoSitePlus	TCGA;ICGC;COSMIC	24.279	Up-regulation
AGC_RSK_RSKp70_RPS6KB1_ST	Q9BYV9	BACH2	P23443	RPS6KB1	S525	D531E	531	Missense	distal	6	no	30.986	31.603	EPSD	TCGA;ICGC;COSMIC	24.279	Up-regulation
AGC_RSK_RSKp70_RPS6KB1_ST	Q9BYV9	BACH2	P23443	RPS6KB1	S525	A529V	529	Missense	distal	4	no	30.986	30.276	EPSD	TCGA;ICGC;COSMIC;CCLE	24.279	Down-regulation
AGC_RSK_RSKp70_RPS6KB1_ST	Q9BYV9	BACH2	P23443	RPS6KB1	S525	A529T	529	Missense	distal	4	no	30.986	30.740	EPSD	TCGA;ICGC;COSMIC	24.279	Down-regulation
AGC_RSK_RSKp70_RPS6KB1_ST	Q9BYV9	BACH2	P23443	RPS6KB1	S525	G532R	532	Missense	distal	7	no	30.986	30.831	EPSD	TCGA;ICGC;COSMIC	24.279	Down-regulation
AGC_RSK_RSKp70_RPS6KB1_ST	Q9BYV9	BACH2	P23443	RPS6KB1	S527	D531E	531	Missense	distal	4	no	26.399	26.306	EPSD	TCGA;ICGC;COSMIC	24.279	Down-regulation
AGC_RSK_RSKp70_RPS6KB1_ST	Q9BYV9	BACH2	P23443	RPS6KB1	S527	A529V	529	Missense	proximal	2	no	26.399	25.563	EPSD	TCGA;ICGC;COSMIC;CCLE	24.279	Down-regulation
AGC_RSK_RSKp70_RPS6KB1_ST	Q9BYV9	BACH2	P23443	RPS6KB1	S527	S525T	525	Missense	proximal	-2	no	26.399	27.449	EPSD	TCGA;ICGC;COSMIC	24.279	Up-regulation
AGC_RSK_RSKp70_RPS6KB1_ST	Q9BYV9	BACH2	P23443	RPS6KB1	S527	A529T	529	Missense	proximal	2	no	26.399	28.363	EPSD	TCGA;ICGC;COSMIC	24.279	Up-regulation
AGC_RSK_RSKp70_RPS6KB1_ST	Q9BYV9	BACH2	P23443	RPS6KB1	S527	G532R	532	Missense	distal	5	no	26.399	25.638	EPSD	TCGA;ICGC;COSMIC	24.279	Down-regulation
AGC_RSK_RSKp70_RPS6KB1_ST	Q9BYV9	BACH2	P23443	RPS6KB1	S527	S533R	533	Missense	distal	6	no	26.399	25.821	EPSD	TCGA;ICGC;COSMIC	24.279	Down-regulation
AGC_RSK_RSKp70_RPS6KB1_ST	Q9BYV9	BACH2	P23443	RPS6KB1	S536	S533R	533	Missense	distal	-3	no	15.289	24.773	EPSD	TCGA;ICGC;COSMIC	24.279	Gain
AGC_RSK_RSKp70_RPS6KB1_ST	P35568	IRS1	P23443	RPS6KB1	S270	E263K	263	Missense	distal	-7	no	44.958	45.060	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	24.279	Up-regulation
AGC_RSK_RSKp70_RPS6KB1_ST	P35568	IRS1	P23443	RPS6KB1	S270	K269N	269	Missense	proximal	-1	no	44.958	44.961	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	24.279	Up-regulation
AGC_RSK_RSKp70_RPS6KB1_ST	P35568	IRS1	P23443	RPS6KB1	S270	P266S	266	Missense	distal	-4	no	44.958	46.623	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	24.279	Up-regulation
AGC_RSK_RSKp70_RPS6KB1_ST	P35568	IRS1	P23443	RPS6KB1	S270	C276F	276	Missense	distal	6	no	44.958	43.947	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	24.279	Down-regulation
AGC_RSK_RSKp70_RPS6KB1_ST	P35568	IRS1	P23443	RPS6KB1	S270	N275S	275	Missense	distal	5	no	44.958	47.996	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	24.279	Up-regulation
AGC_RSK_RSKp70_RPS6KB1_ST	P35568	IRS1	P23443	RPS6KB1	S272	K269N	269	Missense	distal	-3	no	27.405	26.073	EPSD	TCGA;ICGC;COSMIC	24.279	Down-regulation
AGC_RSK_RSKp70_RPS6KB1_ST	P35568	IRS1	P23443	RPS6KB1	S272	P266S	266	Missense	distal	-6	no	27.405	27.354	EPSD	TCGA;ICGC;COSMIC	24.279	Down-regulation
AGC_RSK_RSKp70_RPS6KB1_ST	P35568	IRS1	P23443	RPS6KB1	S272	C276F	276	Missense	distal	4	no	27.405	27.094	EPSD	TCGA;ICGC;COSMIC	24.279	Down-regulation
AGC_RSK_RSKp70_RPS6KB1_ST	P35568	IRS1	P23443	RPS6KB1	S272	N275S	275	Missense	distal	3	no	27.405	28.243	EPSD	TCGA;ICGC;COSMIC	24.279	Up-regulation
AGC_RSK_RSKp70_RPS6KB1_ST	P35568	IRS1	P23443	RPS6KB1	S307	A314G	314	Missense	distal	7	no	46.236	46.171	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	24.279	Down-regulation
AGC_RSK_RSKp70_RPS6KB1_ST	P35568	IRS1	P23443	RPS6KB1	T309	A314G	314	Missense	distal	5	no	25.015	25.606	EPSD	TCGA;ICGC;COSMIC	24.279	Up-regulation
AGC_RSK_RSKp70_RPS6KB1_ST	P35568	IRS1	P23443	RPS6KB1	S312	A314G	314	Missense	proximal	2	no	35.163	36.216	EPSD	TCGA;ICGC;COSMIC	24.279	Up-regulation
AGC_RSK_RSKp70_RPS6KB1_ST	P35568	IRS1	P23443	RPS6KB1	S330	R327H	327	Missense	distal	-3	no	34.184	30.696	EPSD	TCGA;ICGC	24.279	Down-regulation
AGC_RSK_RSKp70_RPS6KB1_ST	P35568	IRS1	P23443	RPS6KB1	S330	D331V	331	Missense	proximal	1	no	34.184	34.330	EPSD	TCGA;ICGC;COSMIC	24.279	Up-regulation
AGC_RSK_RSKp70_RPS6KB1_ST	P35568	IRS1	P23443	RPS6KB1	S330	T335I	335	Missense	distal	5	no	34.184	31.978	EPSD	TCGA;ICGC;COSMIC	24.279	Down-regulation
AGC_RSK_RSKp70_RPS6KB1_ST	P35568	IRS1	P23443	RPS6KB1	S330	A328T	328	Missense	proximal	-2	no	34.184	34.159	EPSD	TCGA;ICGC;COSMIC	24.279	Down-regulation
AGC_RSK_RSKp70_RPS6KB1_ST	P35568	IRS1	P23443	RPS6KB1	S330	S330N	330	Missense	central	0	yes	34.184	0.000	EPSD	TCGA;ICGC;COSMIC	24.279	Loss
AGC_RSK_RSKp70_RPS6KB1_ST	P35568	IRS1	P23443	RPS6KB1	S330	S323A	323	Missense	distal	-7	no	34.184	34.332	EPSD	TCGA;ICGC;COSMIC	24.279	Up-regulation
AGC_RSK_RSKp70_RPS6KB1_ST	P35568	IRS1	P23443	RPS6KB1	S341	T335I	335	Missense	distal	-6	no	28.623	28.664	EPSD	TCGA;ICGC;COSMIC	24.279	Up-regulation
AGC_RSK_RSKp70_RPS6KB1_ST	P35568	IRS1	P23443	RPS6KB1	S341	R338H	338	Missense	distal	-3	no	28.623	25.134	EPSD	TCGA;ICGC;COSMIC	24.279	Down-regulation
AGC_RSK_RSKp70_RPS6KB1_ST	P35568	IRS1	P23443	RPS6KB1	S341	R338C	338	Missense	distal	-3	no	28.623	19.074	EPSD	TCGA;ICGC;COSMIC	24.279	Loss
AGC_RSK_RSKp70_RPS6KB1_ST	P35568	IRS1	P23443	RPS6KB1	S341	P346H	346	Missense	distal	5	no	28.623	28.961	EPSD	TCGA;ICGC	24.279	Up-regulation
AGC_RSK_RSKp70_RPS6KB1_ST	P35568	IRS1	P23443	RPS6KB1	S362	A363D	363	Missense	proximal	1	no	27.313	28.221	EPSD	TCGA;ICGC;COSMIC	24.279	Up-regulation
AGC_RSK_RSKp70_RPS6KB1_ST	P35568	IRS1	P23443	RPS6KB1	S362	A356T	356	Missense	distal	-6	no	27.313	27.296	EPSD	TCGA;ICGC;COSMIC	24.279	Down-regulation
AGC_RSK_RSKp70_RPS6KB1_ST	P35568	IRS1	P23443	RPS6KB1	S362	A363T	363	Missense	proximal	1	no	27.313	28.431	EPSD	TCGA;ICGC;COSMIC	24.279	Up-regulation
AGC_RSK_RSKp70_RPS6KB1_ST	P35568	IRS1	P23443	RPS6KB1	S362	R360W	360	Missense	proximal	-2	no	27.313	28.230	EPSD	TCGA;ICGC;CCLE	24.279	Up-regulation
AGC_RSK_RSKp70_RPS6KB1_ST	P35568	IRS1	P23443	RPS6KB1	S362	H359R	359	Missense	distal	-3	no	27.313	30.802	EPSD	TCGA;ICGC	24.279	Up-regulation
AGC_RSK_RSKp70_RPS6KB1_ST	P35568	IRS1	P23443	RPS6KB1	S372	R373C	373	Missense	proximal	1	no	31.118	32.064	EPSD	TCGA;ICGC;COSMIC	24.279	Up-regulation
AGC_RSK_RSKp70_RPS6KB1_ST	P35568	IRS1	P23443	RPS6KB1	S372	P378S	378	Missense	distal	6	no	31.118	32.093	EPSD	TCGA;ICGC;COSMIC	24.279	Up-regulation
AGC_RSK_RSKp70_RPS6KB1_ST	P35568	IRS1	P23443	RPS6KB1	S391	P389L	389	Missense	proximal	-2	no	27.826	26.061	EPSD	TCGA;ICGC;COSMIC	24.279	Down-regulation
AGC_RSK_RSKp70_RPS6KB1_ST	P35568	IRS1	P23443	RPS6KB1	S391	S395C	395	Missense	distal	4	no	27.826	25.975	EPSD	TCGA;ICGC;COSMIC	24.279	Down-regulation
AGC_RSK_RSKp70_RPS6KB1_ST	P35568	IRS1	P23443	RPS6KB1	S391	P384H	384	Missense	distal	-7	no	27.826	27.712	EPSD	TCGA;ICGC;COSMIC	24.279	Down-regulation
AGC_RSK_RSKp70_RPS6KB1_ST	P35568	IRS1	P23443	RPS6KB1	S396	P389L	389	Missense	distal	-7	no	26.269	26.205	EPSD	TCGA;ICGC;COSMIC	24.279	Down-regulation
AGC_RSK_RSKp70_RPS6KB1_ST	P35568	IRS1	P23443	RPS6KB1	S396	S395C	395	Missense	proximal	-1	no	26.269	26.371	EPSD	TCGA;ICGC;COSMIC	24.279	Up-regulation
AGC_RSK_RSKp70_RPS6KB1_ST	P35568	IRS1	P23443	RPS6KB1	S398	S395C	395	Missense	distal	-3	no	27.473	27.407	EPSD	TCGA;ICGC;COSMIC	24.279	Down-regulation
AGC_RSK_RSKp70_RPS6KB1_ST	P35568	IRS1	P23443	RPS6KB1	S402	S395C	395	Missense	distal	-7	no	26.489	26.653	EPSD	TCGA;ICGC;COSMIC	24.279	Up-regulation
AGC_RSK_RSKp70_RPS6KB1_ST	P35568	IRS1	P23443	RPS6KB1	S415	R411Q	411	Missense	distal	-4	no	39.075	37.055	EPSD	TCGA;ICGC	24.279	Down-regulation
AGC_RSK_RSKp70_RPS6KB1_ST	P35568	IRS1	P23443	RPS6KB1	S440	F438V	438	Missense	proximal	-2	no	26.414	26.200	EPSD	TCGA;ICGC;COSMIC	24.279	Down-regulation
AGC_RSK_RSKp70_RPS6KB1_ST	P35568	IRS1	P23443	RPS6KB1	S440	V445I	445	Missense	distal	5	no	26.414	25.716	EPSD	TCGA;ICGC;COSMIC	24.279	Down-regulation
AGC_RSK_RSKp70_RPS6KB1_ST	P35568	IRS1	P23443	RPS6KB1	S440	R443H	443	Missense	distal	3	no	26.414	26.022	EPSD	TCGA;ICGC	24.279	Down-regulation
AGC_RSK_RSKp70_RPS6KB1_ST	P35568	IRS1	P23443	RPS6KB1	S444	F438V	438	Missense	distal	-6	no	29.880	29.857	EPSD	TCGA;ICGC;COSMIC	24.279	Down-regulation
AGC_RSK_RSKp70_RPS6KB1_ST	P35568	IRS1	P23443	RPS6KB1	S444	V445I	445	Missense	proximal	1	no	29.880	29.916	EPSD	TCGA;ICGC;COSMIC	24.279	Up-regulation
AGC_RSK_RSKp70_RPS6KB1_ST	P35568	IRS1	P23443	RPS6KB1	S444	R443H	443	Missense	proximal	-1	no	29.880	29.898	EPSD	TCGA;ICGC	24.279	Up-regulation
AGC_RSK_RSKp70_RPS6KB1_ST	P35568	IRS1	P23443	RPS6KB1	T446	V445I	445	Missense	proximal	-1	no	26.985	26.975	EPSD	TCGA;ICGC;COSMIC	24.279	Down-regulation
AGC_RSK_RSKp70_RPS6KB1_ST	P35568	IRS1	P23443	RPS6KB1	T446	R443H	443	Missense	distal	-3	no	26.985	23.497	EPSD	TCGA;ICGC	24.279	Loss
AGC_RSK_RSKp70_RPS6KB1_ST	P35568	IRS1	P23443	RPS6KB1	T498	T498I	498	Missense	central	0	yes	28.427	0.000	EPSD	TCGA;ICGC;COSMIC	24.279	Loss
AGC_RSK_RSKp70_RPS6KB1_ST	P35568	IRS1	P23443	RPS6KB1	T498	P504A	504	Missense	distal	6	no	28.427	28.282	EPSD	TCGA;ICGC;COSMIC	24.279	Down-regulation
AGC_RSK_RSKp70_RPS6KB1_ST	P35568	IRS1	P23443	RPS6KB1	T525	R520W	520	Missense	distal	-5	no	28.631	16.668	EPSD	TCGA;ICGC;COSMIC	24.279	Loss
AGC_RSK_RSKp70_RPS6KB1_ST	P35568	IRS1	P23443	RPS6KB1	T525	R522Q	522	Missense	distal	-3	no	28.631	9.576	EPSD	TCGA;ICGC;COSMIC	24.279	Loss
AGC_RSK_RSKp70_RPS6KB1_ST	P35568	IRS1	P23443	RPS6KB1	T525	R520Q	520	Missense	distal	-5	no	28.631	16.656	EPSD	TCGA;ICGC;COSMIC	24.279	Loss
AGC_RSK_RSKp70_RPS6KB1_ST	P35568	IRS1	P23443	RPS6KB1	S527	R520W	520	Missense	distal	-7	no	36.607	36.811	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	24.279	Up-regulation
AGC_RSK_RSKp70_RPS6KB1_ST	P35568	IRS1	P23443	RPS6KB1	S527	R522Q	522	Missense	distal	-5	no	36.607	24.632	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	24.279	Down-regulation
AGC_RSK_RSKp70_RPS6KB1_ST	P35568	IRS1	P23443	RPS6KB1	S527	R520Q	520	Missense	distal	-7	no	36.607	36.677	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	24.279	Up-regulation
AGC_RSK_RSKp70_RPS6KB1_ST	P35568	IRS1	P23443	RPS6KB1	S603	H607R	607	Missense	distal	4	no	29.002	28.940	EPSD	TCGA;ICGC	24.279	Down-regulation
AGC_RSK_RSKp70_RPS6KB1_ST	P35568	IRS1	P23443	RPS6KB1	S603	R600C	600	Missense	distal	-3	no	29.002	19.453	EPSD	TCGA;ICGC;COSMIC	24.279	Loss
AGC_RSK_RSKp70_RPS6KB1_ST	P35568	IRS1	P23443	RPS6KB1	S604	H607R	607	Missense	distal	3	no	24.894	25.287	EPSD	TCGA;ICGC	24.279	Up-regulation
AGC_RSK_RSKp70_RPS6KB1_ST	P35568	IRS1	P23443	RPS6KB1	S604	G611C	611	Missense	distal	7	no	24.894	23.738	EPSD	TCGA;ICGC;COSMIC	24.279	Loss
AGC_RSK_RSKp70_RPS6KB1_ST	P35568	IRS1	P23443	RPS6KB1	S604	R600C	600	Missense	distal	-4	no	24.894	23.501	EPSD	TCGA;ICGC;COSMIC	24.279	Loss
AGC_RSK_RSKp70_RPS6KB1_ST	P35568	IRS1	P23443	RPS6KB1	T605	H607R	607	Missense	proximal	2	no	27.836	27.315	EPSD	TCGA;ICGC	24.279	Down-regulation
AGC_RSK_RSKp70_RPS6KB1_ST	P35568	IRS1	P23443	RPS6KB1	T605	G611C	611	Missense	distal	6	no	27.836	26.666	EPSD	TCGA;ICGC;COSMIC	24.279	Down-regulation
AGC_RSK_RSKp70_RPS6KB1_ST	P35568	IRS1	P23443	RPS6KB1	T605	R600C	600	Missense	distal	-5	no	27.836	18.603	EPSD	TCGA;ICGC;COSMIC	24.279	Loss
AGC_RSK_RSKp70_RPS6KB1_ST	P35568	IRS1	P23443	RPS6KB1	S616	G611C	611	Missense	distal	-5	no	35.731	33.743	EPSD	TCGA;ICGC;COSMIC	24.279	Down-regulation
AGC_RSK_RSKp70_RPS6KB1_ST	P35568	IRS1	P23443	RPS6KB1	S668	I675V	675	Missense	distal	7	no	24.578	24.442	EPSD	TCGA;ICGC;COSMIC	24.279	Down-regulation
AGC_RSK_RSKp70_RPS6KB1_ST	P35568	IRS1	P23443	RPS6KB1	S668	S672C	672	Missense	distal	4	no	24.578	22.727	EPSD	TCGA;ICGC;COSMIC	24.279	Loss
AGC_RSK_RSKp70_RPS6KB1_ST	P35568	IRS1	P23443	RPS6KB1	S672	G676E	676	Missense	distal	4	no	24.150	24.566	EPSD	TCGA	24.279	Gain
AGC_RSK_RSKp70_RPS6KB1_ST	P35568	IRS1	P23443	RPS6KB1	S680	I675V	675	Missense	distal	-5	no	22.867	25.254	EPSD	TCGA;ICGC;COSMIC	24.279	Gain
AGC_RSK_RSKp70_RPS6KB1_ST	P35568	IRS1	P23443	RPS6KB1	S680	G676E	676	Missense	distal	-4	no	22.867	24.411	EPSD	TCGA	24.279	Gain
AGC_RSK_RSKp70_RPS6KB1_ST	P35568	IRS1	P23443	RPS6KB1	S736	D731E	731	Missense	distal	-5	no	22.317	26.207	EPSD	TCGA;ICGC;COSMIC	24.279	Gain
AGC_RSK_RSKp70_RPS6KB1_ST	P35568	IRS1	P23443	RPS6KB1	S763	S770Y	770	Missense	distal	7	no	29.109	28.411	EPSD	TCGA;ICGC;COSMIC	24.279	Down-regulation
AGC_RSK_RSKp70_RPS6KB1_ST	P35568	IRS1	P23443	RPS6KB1	S763	R769K	769	Missense	distal	6	no	29.109	28.957	EPSD	TCGA;ICGC;COSMIC	24.279	Down-regulation
AGC_RSK_RSKp70_RPS6KB1_ST	P35568	IRS1	P23443	RPS6KB1	T793	R797C	797	Missense	distal	4	no	26.941	26.293	EPSD	TCGA;ICGC;COSMIC	24.279	Down-regulation
AGC_RSK_RSKp70_RPS6KB1_ST	P35568	IRS1	P23443	RPS6KB1	T1103	S1109C	1109	Missense	distal	6	no	30.220	29.217	EPSD	TCGA;ICGC;COSMIC	24.279	Down-regulation
AGC_RSK_RSKp70_RPS6KB1_ST	P35568	IRS1	P23443	RPS6KB1	S1105	S1109C	1109	Missense	distal	4	no	32.740	30.889	EPSD	TCGA;ICGC;COSMIC	24.279	Down-regulation
AGC_RSK_RSKp70_RPS6KB1_ST	P35568	IRS1	P23443	RPS6KB1	S1106	S1109C	1109	Missense	distal	3	no	27.271	24.033	EPSD	TCGA;ICGC;COSMIC	24.279	Loss
AGC_RSK_RSKp70_RPS6KB1_ST	Q15633	TARBP2	P23443	RPS6KB1	S112	S112F	112	Missense	central	0	yes	27.759	0.000	EPSD	TCGA;ICGC;COSMIC	24.279	Loss
AGC_RSK_RSKp70_RPS6KB1_ST	Q15633	TARBP2	P23443	RPS6KB1	S112	S116C	116	Missense	distal	4	no	27.759	25.909	EPSD	TCGA;COSMIC	24.279	Down-regulation
AGC_RSK_RSKp70_RPS6KB1_ST	Q15633	TARBP2	P23443	RPS6KB1	T179	R174Q	174	Missense	distal	-5	no	27.098	15.123	EPSD	TCGA;COSMIC	24.279	Loss
AGC_RSK_RSKp70_RPS6KB1_ST	Q15633	TARBP2	P23443	RPS6KB1	T179	P186T	186	Missense	distal	7	no	27.098	26.907	EPSD	TCGA;COSMIC	24.279	Down-regulation
AGC_RSK_RSKp70_RPS6KB1_ST	Q15633	TARBP2	P23443	RPS6KB1	T179	P186S	186	Missense	distal	7	no	27.098	27.572	EPSD	TCGA;COSMIC	24.279	Up-regulation
AGC_RSK_RSKp70_RPS6KB1_ST	Q15633	TARBP2	P23443	RPS6KB1	S246	R252C	252	Missense	distal	6	no	24.770	24.343	EPSD	TCGA;COSMIC	24.279	Down-regulation
AGC_RSK_RSKp70_RPS6KB1_ST	Q15633	TARBP2	P23443	RPS6KB1	S283	S286C	286	Missense	distal	3	no	39.175	35.936	PhosphoSitePlus	TCGA;COSMIC	24.279	Down-regulation
AGC_RSK_RSKp70_RPS6KB1_ST	P42345	MTOR	P23443	RPS6KB1	T15	V21I	21	Missense	distal	6	no	26.287	26.387	EPSD	TCGA;ICGC;COSMIC	24.279	Up-regulation
AGC_RSK_RSKp70_RPS6KB1_ST	P42345	MTOR	P23443	RPS6KB1	T15	A8S	8	Missense	distal	-7	no	26.287	26.139	EPSD	TCGA;ICGC;COSMIC	24.279	Down-regulation
AGC_RSK_RSKp70_RPS6KB1_ST	P42345	MTOR	P23443	RPS6KB1	T714	R717Q	717	Missense	distal	3	no	25.169	23.842	EPSD	TCGA;ICGC;COSMIC	24.279	Loss
AGC_RSK_RSKp70_RPS6KB1_ST	P42345	MTOR	P23443	RPS6KB1	T714	E709G	709	Missense	distal	-5	no	25.169	22.524	EPSD	TCGA;ICGC;COSMIC	24.279	Loss
AGC_RSK_RSKp70_RPS6KB1_ST	P42345	MTOR	P23443	RPS6KB1	S831	Q838L	838	Missense	distal	7	no	25.316	24.750	EPSD	TCGA;ICGC;COSMIC	24.279	Down-regulation
AGC_RSK_RSKp70_RPS6KB1_ST	P42345	MTOR	P23443	RPS6KB1	S831	A835S	835	Missense	distal	4	no	25.316	25.819	EPSD	TCGA;ICGC;COSMIC	24.279	Up-regulation
AGC_RSK_RSKp70_RPS6KB1_ST	P42345	MTOR	P23443	RPS6KB1	T880	R881H	881	Missense	proximal	1	no	25.228	24.821	EPSD	TCGA;ICGC;COSMIC	24.279	Down-regulation
AGC_RSK_RSKp70_RPS6KB1_ST	P42345	MTOR	P23443	RPS6KB1	T880	R886H	886	Missense	distal	6	no	25.228	25.623	EPSD	TCGA;ICGC;COSMIC	24.279	Up-regulation
AGC_RSK_RSKp70_RPS6KB1_ST	P42345	MTOR	P23443	RPS6KB1	T880	R881C	881	Missense	proximal	1	no	25.228	26.174	EPSD	TCGA;ICGC;COSMIC	24.279	Up-regulation
AGC_RSK_RSKp70_RPS6KB1_ST	P42345	MTOR	P23443	RPS6KB1	T880	R886S	886	Missense	distal	6	no	25.228	25.805	EPSD	TCGA;ICGC	24.279	Up-regulation
AGC_RSK_RSKp70_RPS6KB1_ST	P42345	MTOR	P23443	RPS6KB1	S913	R910Q	910	Missense	distal	-3	no	25.034	5.978	EPSD	TCGA;ICGC;COSMIC	24.279	Loss
AGC_RSK_RSKp70_RPS6KB1_ST	P42345	MTOR	P23443	RPS6KB1	S913	V915F	915	Missense	proximal	2	no	25.034	23.533	EPSD	TCGA;ICGC;COSMIC	24.279	Loss
AGC_RSK_RSKp70_RPS6KB1_ST	P42345	MTOR	P23443	RPS6KB1	S1179	T1176M	1176	Missense	distal	-3	no	21.621	26.073	EPSD	TCGA;ICGC;COSMIC	24.279	Gain
AGC_RSK_RSKp70_RPS6KB1_ST	P42345	MTOR	P23443	RPS6KB1	S1239	Q1241R	1241	Missense	proximal	2	no	23.129	24.936	EPSD	TCGA;ICGC;COSMIC	24.279	Gain
AGC_RSK_RSKp70_RPS6KB1_ST	P42345	MTOR	P23443	RPS6KB1	S1849	E1845K	1845	Missense	distal	-4	no	24.227	25.618	EPSD	TCGA;ICGC;COSMIC	24.279	Gain
AGC_RSK_RSKp70_RPS6KB1_ST	P42345	MTOR	P23443	RPS6KB1	S1855	T1856I	1856	Missense	proximal	1	no	30.105	30.077	EPSD	TCGA;ICGC;COSMIC	24.279	Down-regulation
AGC_RSK_RSKp70_RPS6KB1_ST	P42345	MTOR	P23443	RPS6KB1	S1855	E1857K	1857	Missense	proximal	2	no	30.105	31.763	EPSD	TCGA;ICGC;COSMIC;CCLE	24.279	Up-regulation
AGC_RSK_RSKp70_RPS6KB1_ST	P42345	MTOR	P23443	RPS6KB1	T1861	E1857K	1857	Missense	distal	-4	no	23.472	24.863	EPSD	TCGA;ICGC;COSMIC;CCLE	24.279	Gain
AGC_RSK_RSKp70_RPS6KB1_ST	P42345	MTOR	P23443	RPS6KB1	S1893	R1896Q	1896	Missense	distal	3	no	24.886	23.560	EPSD	TCGA;ICGC;COSMIC	24.279	Loss
AGC_RSK_RSKp70_RPS6KB1_ST	P42345	MTOR	P23443	RPS6KB1	S1893	R1890C	1890	Missense	distal	-3	no	24.886	15.337	EPSD	TCGA;ICGC;COSMIC;CCLE	24.279	Loss
AGC_RSK_RSKp70_RPS6KB1_ST	P42345	MTOR	P23443	RPS6KB1	S1893	N1898S	1898	Missense	distal	5	no	24.886	27.924	EPSD	TCGA;ICGC;COSMIC	24.279	Up-regulation
AGC_RSK_RSKp70_RPS6KB1_ST	P42345	MTOR	P23443	RPS6KB1	S1893	F1888L	1888	Missense	distal	-5	no	24.886	27.573	EPSD	TCGA;ICGC;COSMIC	24.279	Up-regulation
AGC_RSK_RSKp70_RPS6KB1_ST	P42345	MTOR	P23443	RPS6KB1	S1893	F1888V	1888	Missense	distal	-5	no	24.886	27.414	EPSD	TCGA;ICGC;COSMIC;GDSC;CCLE	24.279	Up-regulation
AGC_RSK_RSKp70_RPS6KB1_ST	P42345	MTOR	P23443	RPS6KB1	T2446	R2441Q	2441	Missense	distal	-5	no	37.773	25.798	PhosphoSitePlus;EPSD	TCGA;ICGC;COSMIC	24.279	Down-regulation
AGC_RSK_RSKp70_RPS6KB1_ST	P42345	MTOR	P23443	RPS6KB1	S2448	R2441Q	2441	Missense	distal	-7	no	38.831	38.901	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	24.279	Up-regulation
AGC_RSK_RSKp70_RPS6KB1_ST	P42345	MTOR	P23443	RPS6KB1	T2474	T2471M	2471	Missense	distal	-3	no	21.692	26.144	EPSD	TCGA;COSMIC;GDSC;CCLE	24.279	Gain
AGC_RSK_RSKp70_RPS6KB1_ST	P42345	MTOR	P23443	RPS6KB1	S2514	D2516Y	2516	Missense	proximal	2	no	25.147	24.375	EPSD	TCGA;ICGC;COSMIC	24.279	Down-regulation
AGC_RSK_RSKp70_RPS6KB1_ST	P42345	MTOR	P23443	RPS6KB1	S2514	D2512Y	2512	Missense	proximal	-2	no	25.147	24.420	EPSD	TCGA;ICGC;COSMIC	24.279	Down-regulation
AGC_RSK_RSKp70_RPS6KB1_ST	Q06787	FMR1	P23443	RPS6KB1	S191	T194S	194	Missense	distal	3	no	30.707	32.553	EPSD	TCGA	24.279	Up-regulation
AGC_RSK_RSKp70_RPS6KB1_ST	Q06787	FMR1	P23443	RPS6KB1	S191	R193H	193	Missense	proximal	2	no	30.707	31.228	EPSD	TCGA;ICGC;COSMIC	24.279	Up-regulation
AGC_RSK_RSKp70_RPS6KB1_ST	Q06787	FMR1	P23443	RPS6KB1	S191	M187L	187	Missense	distal	-4	no	30.707	30.045	EPSD	TCGA;ICGC;COSMIC	24.279	Down-regulation
AGC_RSK_RSKp70_RPS6KB1_ST	Q06787	FMR1	P23443	RPS6KB1	S191	L196V	196	Missense	distal	5	no	30.707	29.026	EPSD	TCGA;ICGC;COSMIC	24.279	Down-regulation
AGC_RSK_RSKp70_RPS6KB1_ST	Q06787	FMR1	P23443	RPS6KB1	S191	R190Q	190	Missense	proximal	-1	no	30.707	30.736	EPSD	TCGA;ICGC;COSMIC	24.279	Up-regulation
AGC_RSK_RSKp70_RPS6KB1_ST	Q06787	FMR1	P23443	RPS6KB1	S191	R193S	193	Missense	proximal	2	no	30.707	32.810	EPSD	TCGA;ICGC;COSMIC	24.279	Up-regulation
AGC_RSK_RSKp70_RPS6KB1_ST	Q06787	FMR1	P23443	RPS6KB1	S460	R454C	454	Missense	distal	-6	no	28.019	28.059	EPSD	TCGA;ICGC;COSMIC	24.279	Up-regulation
AGC_RSK_RSKp70_RPS6KB1_ST	Q06787	FMR1	P23443	RPS6KB1	S460	T455K	455	Missense	distal	-5	no	28.019	29.833	EPSD	TCGA;ICGC;COSMIC	24.279	Up-regulation
AGC_RSK_RSKp70_RPS6KB1_ST	Q06787	FMR1	P23443	RPS6KB1	S460	R454P	454	Missense	distal	-6	no	28.019	28.063	EPSD	TCGA;ICGC;COSMIC	24.279	Up-regulation
AGC_RSK_RSKp70_RPS6KB1_ST	Q06787	FMR1	P23443	RPS6KB1	S460	R454H	454	Missense	distal	-6	no	28.019	28.033	EPSD	TCGA;ICGC;COSMIC	24.279	Up-regulation
AGC_RSK_RSKp70_RPS6KB1_ST	Q06787	FMR1	P23443	RPS6KB1	S460	E458K	458	Missense	proximal	-2	no	28.019	27.698	EPSD	TCGA;ICGC;COSMIC	24.279	Down-regulation
AGC_RSK_RSKp70_RPS6KB1_ST	Q06787	FMR1	P23443	RPS6KB1	S460	D464G	464	Missense	distal	4	no	28.019	27.510	EPSD	TCGA;ICGC;COSMIC	24.279	Down-regulation
AGC_RSK_RSKp70_RPS6KB1_ST	Q06787	FMR1	P23443	RPS6KB1	S500	S500F	500	Missense	central	0	yes	34.017	0.000	PhosphoSitePlus	TCGA;ICGC;COSMIC	24.279	Loss
AGC_RSK_RSKp70_RPS6KB1_ST	Q06787	FMR1	P23443	RPS6KB1	T598	R604L	604	Missense	distal	6	no	26.450	26.872	EPSD	TCGA;COSMIC	24.279	Up-regulation
AGC_RSK_RSKp70_RPS6KB1_ST	Q06787	FMR1	P23443	RPS6KB1	T598	R604W	604	Missense	distal	6	no	26.450	25.809	EPSD	TCGA	24.279	Down-regulation
AGC_RSK_RSKp70_RPS6KB1_ST	Q9UN36	NDRG2	P23443	RPS6KB1	S344	R345H	345	Missense	proximal	1	no	27.128	26.721	EPSD	TCGA	24.279	Down-regulation
AGC_RSK_RSKp70_RPS6KB1_ST	Q9UN36	NDRG2	P23443	RPS6KB1	S346	R345H	345	Missense	proximal	-1	no	30.746	30.764	EPSD	TCGA	24.279	Up-regulation
AGC_RSK_RSKp70_RPS6KB1_ST	Q9UN36	NDRG2	P23443	RPS6KB1	T348	R345H	345	Missense	distal	-3	no	34.565	31.077	EPSD	TCGA	24.279	Down-regulation
AGC_RSK_RSKp70_RPS6KB1_ST	Q9UN36	NDRG2	P23443	RPS6KB1	S350	R345H	345	Missense	distal	-5	no	38.747	35.892	PhosphoSitePlus;EPSD	TCGA	24.279	Down-regulation
AGC_RSK_RSKp70_RPS6KB1_ST	Q9UN36	NDRG2	P23443	RPS6KB1	S355	S359Y	359	Missense	distal	4	no	27.881	26.491	EPSD	TCGA;ICGC	24.279	Down-regulation
AGC_RSK_RSKp70_RPS6KB1_ST	Q9UN36	NDRG2	P23443	RPS6KB1	S359	S359Y	359	Missense	central	0	yes	29.144	0.000	EPSD	TCGA;ICGC	24.279	Loss
AGC_RSK_RSKp70_RPS6KB1_ST	P62753	RPS6	P23443	RPS6KB1	T34	A33T	33	Missense	proximal	-1	no	35.593	35.516	EPSD	TCGA;ICGC;COSMIC	24.279	Down-regulation
AGC_RSK_RSKp70_RPS6KB1_ST	P62753	RPS6	P23443	RPS6KB1	T34	D39G	39	Missense	distal	5	no	35.593	37.016	EPSD	TCGA;ICGC;COSMIC	24.279	Up-regulation
AGC_RSK_RSKp70_RPS6KB1_ST	P62753	RPS6	P23443	RPS6KB1	S235	K230N	230	Missense	distal	-5	no	33.709	32.852	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	24.279	Down-regulation
AGC_RSK_RSKp70_RPS6KB1_ST	P62753	RPS6	P23443	RPS6KB1	S235	S236C	236	Missense	proximal	1	no	33.709	35.446	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	24.279	Up-regulation
AGC_RSK_RSKp70_RPS6KB1_ST	P62753	RPS6	P23443	RPS6KB1	S235	R232H	232	Missense	distal	-3	no	33.709	30.221	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	24.279	Down-regulation
AGC_RSK_RSKp70_RPS6KB1_ST	P62753	RPS6	P23443	RPS6KB1	S235	R233I	233	Missense	proximal	-2	no	33.709	34.127	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	24.279	Up-regulation
AGC_RSK_RSKp70_RPS6KB1_ST	P62753	RPS6	P23443	RPS6KB1	S235	R232C	232	Missense	distal	-3	no	33.709	24.160	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	24.279	Loss
AGC_RSK_RSKp70_RPS6KB1_ST	P62753	RPS6	P23443	RPS6KB1	S236	K230N	230	Missense	distal	-6	no	44.462	44.479	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	24.279	Up-regulation
AGC_RSK_RSKp70_RPS6KB1_ST	P62753	RPS6	P23443	RPS6KB1	S236	S236C	236	Missense	central	0	yes	44.462	0.000	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	24.279	Loss
AGC_RSK_RSKp70_RPS6KB1_ST	P62753	RPS6	P23443	RPS6KB1	S236	R232H	232	Missense	distal	-4	no	44.462	44.007	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	24.279	Down-regulation
AGC_RSK_RSKp70_RPS6KB1_ST	P62753	RPS6	P23443	RPS6KB1	S236	R233I	233	Missense	distal	-3	no	44.462	29.550	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	24.279	Down-regulation
AGC_RSK_RSKp70_RPS6KB1_ST	P62753	RPS6	P23443	RPS6KB1	S236	R232C	232	Missense	distal	-4	no	44.462	43.070	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	24.279	Down-regulation
AGC_RSK_RSKp70_RPS6KB1_ST	P62753	RPS6	P23443	RPS6KB1	S240	S236C	236	Missense	distal	-4	no	32.959	30.508	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	24.279	Down-regulation
AGC_RSK_RSKp70_RPS6KB1_ST	P62753	RPS6	P23443	RPS6KB1	S240	R233I	233	Missense	distal	-7	no	32.959	33.097	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	24.279	Up-regulation
AGC_RSK_RSKp70_RPS6KB1_ST	P62753	RPS6	P23443	RPS6KB1	T241	S236C	236	Missense	distal	-5	no	36.295	32.602	EPSD	TCGA;ICGC;COSMIC	24.279	Down-regulation
AGC_RSK_RSKp70_RPS6KB1_ST	P62753	RPS6	P23443	RPS6KB1	T241	Q248H	248	Missense	distal	7	no	36.295	35.599	EPSD	TCGA;ICGC;COSMIC	24.279	Down-regulation
AGC_RSK_RSKp70_RPS6KB1_ST	P62753	RPS6	P23443	RPS6KB1	S242	S236C	236	Missense	distal	-6	no	28.184	28.230	EPSD	TCGA;ICGC;COSMIC	24.279	Up-regulation
AGC_RSK_RSKp70_RPS6KB1_ST	P62753	RPS6	P23443	RPS6KB1	S242	Q248H	248	Missense	distal	6	no	28.184	28.764	EPSD	TCGA;ICGC;COSMIC	24.279	Up-regulation
AGC_RSK_RSKp70_RPS6KB1_ST	P62753	RPS6	P23443	RPS6KB1	S244	Q248H	248	Missense	distal	4	no	30.542	30.519	PhosphoSitePlus;EPSD	TCGA;ICGC;COSMIC	24.279	Down-regulation
AGC_RSK_RSKp70_RPS6KB1_ST	P49841	GSK3B	P23443	RPS6KB1	S13	Q19R	19	Missense	distal	6	no	27.467	27.653	EPSD	TCGA	24.279	Up-regulation
AGC_RSK_RSKp70_RPS6KB1_ST	P49841	GSK3B	P23443	RPS6KB1	S29	G34S	34	Missense	distal	5	no	25.021	26.157	EPSD	TCGA;COSMIC	24.279	Up-regulation
AGC_RSK_RSKp70_RPS6KB1_ST	P49841	GSK3B	P23443	RPS6KB1	S29	S25N	25	Missense	distal	-4	no	25.021	23.583	EPSD	TCGA;ICGC	24.279	Loss
AGC_RSK_RSKp70_RPS6KB1_ST	P49841	GSK3B	P23443	RPS6KB1	S29	A22S	22	Missense	distal	-7	no	25.021	24.873	EPSD	TCGA;ICGC	24.279	Down-regulation
AGC_RSK_RSKp70_RPS6KB1_ST	P49841	GSK3B	P23443	RPS6KB1	S35	G34S	34	Missense	proximal	-1	no	26.546	26.460	EPSD	TCGA;COSMIC	24.279	Down-regulation
AGC_RSK_RSKp70_RPS6KB1_ST	P49841	GSK3B	P23443	RPS6KB1	S66	T59I	59	Missense	distal	-7	no	29.544	29.670	EPSD	TCGA;ICGC;COSMIC	24.279	Up-regulation
AGC_RSK_RSKp70_RPS6KB1_ST	P49841	GSK3B	P23443	RPS6KB1	S66	G68V	68	Missense	proximal	2	no	29.544	27.655	EPSD	TCGA;ICGC;COSMIC	24.279	Down-regulation
AGC_RSK_RSKp70_RPS6KB1_ST	Q53EL6	PDCD4	P23443	RPS6KB1	S67	S67L	67	Missense	central	0	yes	38.492	0.000	PhosphoSitePlus;EPSD	TCGA;ICGC;COSMIC	24.279	Loss
AGC_RSK_RSKp70_RPS6KB1_ST	Q53EL6	PDCD4	P23443	RPS6KB1	S67	K65T	65	Missense	proximal	-2	no	38.492	38.575	PhosphoSitePlus;EPSD	TCGA;ICGC	24.279	Up-regulation
AGC_RSK_RSKp70_RPS6KB1_ST	Q53EL6	PDCD4	P23443	RPS6KB1	S67	R69Q	69	Missense	proximal	2	no	38.492	36.685	PhosphoSitePlus;EPSD	TCGA;ICGC;COSMIC	24.279	Down-regulation
AGC_RSK_RSKp70_RPS6KB1_ST	Q53EL6	PDCD4	P23443	RPS6KB1	S76	R69Q	69	Missense	distal	-7	no	35.747	35.817	EPSD	TCGA;ICGC;COSMIC	24.279	Up-regulation
AGC_RSK_RSKp70_RPS6KB1_ST	Q53EL6	PDCD4	P23443	RPS6KB1	S305	V300M	300	Missense	distal	-5	no	21.944	27.361	EPSD	TCGA;ICGC	24.279	Gain
AGC_RSK_RSKp70_RPS6KB1_ST	Q53EL6	PDCD4	P23443	RPS6KB1	S313	G308A	308	Missense	distal	-5	no	25.958	25.461	EPSD	TCGA;ICGC;COSMIC	24.279	Down-regulation
AGC_RSK_RSKp70_RPS6KB1_ST	Q53EL6	PDCD4	P23443	RPS6KB1	S313	R310H	310	Missense	distal	-3	no	25.958	22.470	EPSD	TCGA;ICGC;COSMIC	24.279	Loss
AGC_RSK_RSKp70_RPS6KB1_ST	Q53EL6	PDCD4	P23443	RPS6KB1	S457	R463C	463	Missense	distal	6	no	26.949	26.523	EPSD;PhosphoSitePlus	TCGA	24.279	Down-regulation
AGC_RSK_RSKp70_RPS6KB1_ST	Q53EL6	PDCD4	P23443	RPS6KB1	S457	E458Q	458	Missense	proximal	1	no	26.949	26.321	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	24.279	Down-regulation
AGC_RSK_RSKp70_RPS6KB1_ST	Q53EL6	PDCD4	P23443	RPS6KB1	S457	R454L	454	Missense	distal	-3	no	26.949	17.282	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	24.279	Loss
AGC_RSK_RSKp70_RPS6KB1_ST	Q53EL6	PDCD4	P23443	RPS6KB1	S457	E458K	458	Missense	proximal	1	no	26.949	25.367	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	24.279	Down-regulation
AGC_RSK_RSKp70_RPS6KB1_ST	Q53EL6	PDCD4	P23443	RPS6KB1	S468	R463C	463	Missense	distal	-5	no	29.200	19.967	EPSD	TCGA	24.279	Loss
AGC_RSK_RSKp70_RPS6KB1_ST	Q9H3D4	TP63	P23443	RPS6KB1	S389	Q386R	386	Missense	distal	-3	no	5.733	24.789	EPSD	TCGA;COSMIC	24.279	Gain
AGC_RSK_RSKp70_RPS6KB1_ST	Q9H3D4	TP63	P23443	RPS6KB1	S395	D397G	397	Missense	proximal	2	no	23.383	25.071	EPSD	TCGA;COSMIC	24.279	Gain
AGC_RSK_RSKp70_RPS6KB1_ST	Q9H3D4	TP63	P23443	RPS6KB1	S551	A554S	554	Missense	distal	3	no	22.802	25.251	EPSD	TCGA;COSMIC	24.279	Gain
AGC_RSK_RSKp70_RPS6KB1_ST	Q9H3D4	TP63	P23443	RPS6KB1	S551	D546N	546	Missense	distal	-5	no	22.802	24.642	EPSD	TCGA;COSMIC	24.279	Gain
AGC_RSK_RSKp70_RPS6KB1_ST	Q9H3D4	TP63	P23443	RPS6KB1	S560	A554S	554	Missense	distal	-6	no	37.439	37.403	PhosphoSitePlus	TCGA;COSMIC	24.279	Down-regulation
AGC_RSK_RSKp70_RPS6KB1_ST	Q9H3D4	TP63	P23443	RPS6KB1	S560	F565C	565	Missense	distal	5	no	37.439	39.405	PhosphoSitePlus	TCGA;COSMIC	24.279	Up-regulation
AGC_RSK_RSKp70_RPS6KB1_ST	Q9H3D4	TP63	P23443	RPS6KB1	S560	R555W	555	Missense	distal	-5	no	37.439	25.476	PhosphoSitePlus	TCGA;COSMIC	24.279	Down-regulation
AGC_RSK_RSKp70_RPS6KB1_ST	Q9H3D4	TP63	P23443	RPS6KB1	S560	R555K	555	Missense	distal	-5	no	37.439	31.647	PhosphoSitePlus	TCGA;COSMIC	24.279	Down-regulation
AGC_RSK_RSKp70_RPS6KB1_ST	Q9H3D4	TP63	P23443	RPS6KB1	S560	L553I	553	Missense	distal	-7	no	37.439	37.473	PhosphoSitePlus	TCGA;COSMIC	24.279	Up-regulation
AGC_RSK_RSKp70_RPS6KB1_ST	Q9H3D4	TP63	P23443	RPS6KB1	S560	C561G	561	Missense	proximal	1	no	37.439	36.805	PhosphoSitePlus	TCGA	24.279	Down-regulation
AGC_RSK_RSKp70_RPS6KB1_ST	P10636	MAPT	P23443	RPS6KB1	T17	D13N	13	Missense	distal	-4	no	26.536	26.262	EPSD	TCGA;ICGC;COSMIC	24.279	Down-regulation
AGC_RSK_RSKp70_RPS6KB1_ST	P10636	MAPT	P23443	RPS6KB1	T17	R23S	23	Missense	distal	6	no	26.536	27.113	EPSD	TCGA;ICGC;COSMIC	24.279	Up-regulation
AGC_RSK_RSKp70_RPS6KB1_ST	P10636	MAPT	P23443	RPS6KB1	T17	H14Y	14	Missense	distal	-3	no	26.536	13.186	EPSD	TCGA;ICGC;COSMIC	24.279	Loss
AGC_RSK_RSKp70_RPS6KB1_ST	P10636	MAPT	P23443	RPS6KB1	T17	G21W	21	Missense	distal	4	no	26.536	26.131	EPSD	TCGA;ICGC;COSMIC	24.279	Down-regulation
AGC_RSK_RSKp70_RPS6KB1_ST	P10636	MAPT	P23443	RPS6KB1	T17	K24I	24	Missense	distal	7	no	26.536	25.972	EPSD	TCGA;ICGC	24.279	Down-regulation
AGC_RSK_RSKp70_RPS6KB1_ST	P10636	MAPT	P23443	RPS6KB1	S56	P59L	59	Missense	distal	3	no	25.475	26.315	EPSD	TCGA;ICGC;COSMIC	24.279	Up-regulation
AGC_RSK_RSKp70_RPS6KB1_ST	P10636	MAPT	P23443	RPS6KB1	S56	P59T	59	Missense	distal	3	no	25.475	26.169	EPSD	TCGA;ICGC;COSMIC	24.279	Up-regulation
AGC_RSK_RSKp70_RPS6KB1_ST	P10636	MAPT	P23443	RPS6KB1	S56	D54E	54	Missense	proximal	-2	no	25.475	25.093	EPSD	TCGA;ICGC;COSMIC	24.279	Down-regulation
AGC_RSK_RSKp70_RPS6KB1_ST	P10636	MAPT	P23443	RPS6KB1	S56	T52I	52	Missense	distal	-4	no	25.475	25.506	EPSD	TCGA;ICGC;COSMIC	24.279	Up-regulation
AGC_RSK_RSKp70_RPS6KB1_ST	P10636	MAPT	P23443	RPS6KB1	S56	G60S	60	Missense	distal	4	no	25.475	27.068	EPSD	TCGA;ICGC;COSMIC	24.279	Up-regulation
AGC_RSK_RSKp70_RPS6KB1_ST	P10636	MAPT	P23443	RPS6KB1	S56	G55R	55	Missense	proximal	-1	no	25.475	25.419	EPSD	TCGA;ICGC;COSMIC	24.279	Down-regulation
AGC_RSK_RSKp70_RPS6KB1_ST	P10636	MAPT	P23443	RPS6KB1	T69	A72V	72	Missense	distal	3	no	25.024	25.405	EPSD	TCGA;ICGC;COSMIC	24.279	Up-regulation
AGC_RSK_RSKp70_RPS6KB1_ST	P10636	MAPT	P23443	RPS6KB1	T69	A66S	66	Missense	distal	-3	no	25.024	25.461	EPSD	TCGA;ICGC;COSMIC	24.279	Up-regulation
AGC_RSK_RSKp70_RPS6KB1_ST	P10636	MAPT	P23443	RPS6KB1	S171	R168H	168	Missense	distal	-3	no	32.927	29.439	EPSD	TCGA;ICGC;COSMIC	24.279	Down-regulation
AGC_RSK_RSKp70_RPS6KB1_ST	P10636	MAPT	P23443	RPS6KB1	S171	R168C	168	Missense	distal	-3	no	32.927	23.378	EPSD	TCGA;ICGC;COSMIC	24.279	Loss
AGC_RSK_RSKp70_RPS6KB1_ST	P10636	MAPT	P23443	RPS6KB1	S214	P212L	212	Missense	proximal	-2	no	27.785	26.020	PhosphoSitePlus;EPSD	TCGA;ICGC;COSMIC	24.279	Down-regulation
AGC_RSK_RSKp70_RPS6KB1_ST	P10636	MAPT	P23443	RPS6KB1	S214	E220K	220	Missense	distal	6	no	27.785	27.754	PhosphoSitePlus;EPSD	TCGA;ICGC;COSMIC	24.279	Down-regulation
AGC_RSK_RSKp70_RPS6KB1_ST	P10636	MAPT	P23443	RPS6KB1	S232	P234L	234	Missense	proximal	2	no	23.673	24.851	EPSD	TCGA;ICGC;COSMIC	24.279	Gain
AGC_RSK_RSKp70_RPS6KB1_ST	P10636	MAPT	P23443	RPS6KB1	S341	E348V	348	Missense	distal	7	no	38.788	38.116	EPSD	TCGA;ICGC;COSMIC	24.279	Down-regulation
AGC_RSK_RSKp70_RPS6KB1_ST	P10636	MAPT	P23443	RPS6KB1	S341	G339R	339	Missense	proximal	-2	no	38.788	39.654	EPSD	TCGA;ICGC;COSMIC	24.279	Up-regulation
AGC_RSK_RSKp70_RPS6KB1_ST	P10636	MAPT	P23443	RPS6KB1	S341	S341F	341	Missense	central	0	yes	38.788	0.000	EPSD	TCGA;ICGC;COSMIC	24.279	Loss
AGC_RSK_RSKp70_RPS6KB1_ST	P10636	MAPT	P23443	RPS6KB1	S369	Q373R	373	Missense	distal	4	no	30.152	30.066	EPSD	TCGA;ICGC;COSMIC	24.279	Down-regulation
AGC_RSK_RSKp70_RPS6KB1_ST	P10636	MAPT	P23443	RPS6KB1	S369	K366E	366	Missense	distal	-3	no	30.152	27.425	EPSD	TCGA;ICGC;COSMIC	24.279	Down-regulation
AGC_RSK_RSKp70_RPS6KB1_ST	P10636	MAPT	P23443	RPS6KB1	S419	P415L	415	Missense	distal	-4	no	25.020	25.931	EPSD	TCGA;ICGC;COSMIC	24.279	Up-regulation
AGC_RSK_RSKp70_RPS6KB1_ST	P10636	MAPT	P23443	RPS6KB1	S447	K440E	440	Missense	distal	-7	no	29.223	29.121	EPSD	TCGA;ICGC;COSMIC	24.279	Down-regulation
AGC_RSK_RSKp70_RPS6KB1_ST	P10636	MAPT	P23443	RPS6KB1	S447	S452C	452	Missense	distal	5	no	29.223	25.825	EPSD	TCGA;ICGC;COSMIC	24.279	Down-regulation
AGC_RSK_RSKp70_RPS6KB1_ST	P10636	MAPT	P23443	RPS6KB1	S447	S443F	443	Missense	distal	-4	no	29.223	26.595	EPSD	TCGA;ICGC;COSMIC	24.279	Down-regulation
AGC_RSK_RSKp70_RPS6KB1_ST	P10636	MAPT	P23443	RPS6KB1	S447	S444F	444	Missense	distal	-3	no	29.223	25.552	EPSD	TCGA;ICGC	24.279	Down-regulation
AGC_RSK_RSKp70_RPS6KB1_ST	P10636	MAPT	P23443	RPS6KB1	S447	S452Y	452	Missense	distal	5	no	29.223	25.258	EPSD	TCGA;ICGC;COSMIC	24.279	Down-regulation
AGC_RSK_RSKp70_RPS6KB1_ST	P10636	MAPT	P23443	RPS6KB1	S451	E456K	456	Missense	distal	5	no	31.589	31.814	EPSD	TCGA;ICGC;COSMIC	24.279	Up-regulation
AGC_RSK_RSKp70_RPS6KB1_ST	P10636	MAPT	P23443	RPS6KB1	S451	S452C	452	Missense	proximal	1	no	31.589	33.326	EPSD	TCGA;ICGC;COSMIC	24.279	Up-regulation
AGC_RSK_RSKp70_RPS6KB1_ST	P10636	MAPT	P23443	RPS6KB1	S451	S444F	444	Missense	distal	-7	no	31.589	31.951	EPSD	TCGA;ICGC	24.279	Up-regulation
AGC_RSK_RSKp70_RPS6KB1_ST	P10636	MAPT	P23443	RPS6KB1	S451	S452Y	452	Missense	proximal	1	no	31.589	32.953	EPSD	TCGA;ICGC;COSMIC	24.279	Up-regulation
AGC_RSK_RSKp70_RPS6KB1_ST	Q92519	TRIB2	P23443	RPS6KB1	S83	R77C	77	Missense	distal	-6	no	35.522	35.561	PhosphoSitePlus	TCGA;ICGC;COSMIC	24.279	Up-regulation
AGC_RSK_RSKp70_RPS6KB1_ST	Q8TB45	DEPTOR	P23443	RPS6KB1	T59	R53T	53	Missense	distal	-6	no	33.863	33.876	EPSD	TCGA;ICGC;COSMIC	24.279	Up-regulation
AGC_RSK_RSKp70_RPS6KB1_ST	Q8TB45	DEPTOR	P23443	RPS6KB1	T59	R54H	54	Missense	distal	-5	no	33.863	31.008	EPSD	TCGA;ICGC;COSMIC	24.279	Down-regulation
AGC_RSK_RSKp70_RPS6KB1_ST	Q8TB45	DEPTOR	P23443	RPS6KB1	T59	L57P	57	Missense	proximal	-2	no	33.863	35.627	EPSD	TCGA;ICGC	24.279	Up-regulation
AGC_RSK_RSKp70_RPS6KB1_ST	Q8TB45	DEPTOR	P23443	RPS6KB1	S168	F170L	170	Missense	proximal	2	no	23.023	27.047	EPSD	TCGA;COSMIC	24.279	Gain
AGC_RSK_RSKp70_RPS6KB1_ST	Q8TB45	DEPTOR	P23443	RPS6KB1	S238	S244N	244	Missense	distal	6	no	28.362	26.905	EPSD	TCGA;COSMIC	24.279	Down-regulation
AGC_RSK_RSKp70_RPS6KB1_ST	Q8TB45	DEPTOR	P23443	RPS6KB1	S258	M262I	262	Missense	distal	4	no	25.719	25.227	EPSD	TCGA;COSMIC	24.279	Down-regulation
AGC_RSK_RSKp70_RPS6KB1_ST	Q8TB45	DEPTOR	P23443	RPS6KB1	S258	V264L	264	Missense	distal	6	no	25.719	26.788	EPSD	TCGA;COSMIC	24.279	Up-regulation
AGC_RSK_RSKp70_RPS6KB1_ST	Q8TB45	DEPTOR	P23443	RPS6KB1	S258	S265N	265	Missense	distal	7	no	25.719	24.940	EPSD	TCGA;COSMIC	24.279	Down-regulation
AGC_RSK_RSKp70_RPS6KB1_ST	Q8TB45	DEPTOR	P23443	RPS6KB1	S260	V264L	264	Missense	distal	4	no	24.273	25.039	EPSD	TCGA;COSMIC	24.279	Gain
AGC_RSK_RSKp70_RPS6KB1_ST	Q8TB45	DEPTOR	P23443	RPS6KB1	S263	V264L	264	Missense	proximal	1	no	28.945	29.377	EPSD	TCGA;COSMIC	24.279	Up-regulation
AGC_RSK_RSKp70_RPS6KB1_ST	Q8TB45	DEPTOR	P23443	RPS6KB1	S263	S265N	265	Missense	proximal	2	no	28.945	25.442	EPSD	TCGA;COSMIC	24.279	Down-regulation
AGC_RSK_RSKp70_RPS6KB1_ST	Q8TB45	DEPTOR	P23443	RPS6KB1	S283	F290I	290	Missense	distal	7	no	27.189	28.288	EPSD	TCGA;COSMIC	24.279	Up-regulation
AGC_RSK_RSKp70_RPS6KB1_ST	Q8TB45	DEPTOR	P23443	RPS6KB1	S286	F290I	290	Missense	distal	4	no	40.358	41.330	EPSD;PhosphoSitePlus	TCGA;COSMIC	24.279	Up-regulation
AGC_RSK_RSKp70_RPS6KB1_ST	Q8TB45	DEPTOR	P23443	RPS6KB1	S287	F290I	290	Missense	distal	3	no	36.376	37.955	PhosphoSitePlus;EPSD	TCGA;COSMIC	24.279	Up-regulation
AGC_RSK_RSKp70_RPS6KB1_ST	Q8TB45	DEPTOR	P23443	RPS6KB1	S291	F290I	290	Missense	proximal	-1	no	38.136	38.071	EPSD;PhosphoSitePlus	TCGA;COSMIC	24.279	Down-regulation
AGC_RSK_RSKp70_RPS6KB1_ST	Q8TB45	DEPTOR	P23443	RPS6KB1	S389	Y385C	385	Missense	distal	-4	no	29.369	27.942	EPSD	TCGA;COSMIC	24.279	Down-regulation
AGC_RSK_RSKp70_RPS6KB1_ST	O00418	EEF2K	P23443	RPS6KB1	S66	E67K	67	Missense	proximal	1	no	25.313	23.731	EPSD	TCGA;ICGC;COSMIC	24.279	Loss
AGC_RSK_RSKp70_RPS6KB1_ST	O00418	EEF2K	P23443	RPS6KB1	S66	S61G	61	Missense	distal	-5	no	25.313	23.609	EPSD	TCGA;ICGC	24.279	Loss
AGC_RSK_RSKp70_RPS6KB1_ST	O00418	EEF2K	P23443	RPS6KB1	S66	R68W	68	Missense	proximal	2	no	25.313	22.621	EPSD	TCGA	24.279	Loss
AGC_RSK_RSKp70_RPS6KB1_ST	O00418	EEF2K	P23443	RPS6KB1	S66	S61I	61	Missense	distal	-5	no	25.313	19.683	EPSD	TCGA;ICGC	24.279	Loss
AGC_RSK_RSKp70_RPS6KB1_ST	O00418	EEF2K	P23443	RPS6KB1	S70	E67K	67	Missense	distal	-3	no	22.301	25.028	EPSD	TCGA;ICGC;COSMIC	24.279	Gain
AGC_RSK_RSKp70_RPS6KB1_ST	O00418	EEF2K	P23443	RPS6KB1	S71	E67K	67	Missense	distal	-4	no	34.356	35.747	EPSD	TCGA;ICGC;COSMIC	24.279	Up-regulation
AGC_RSK_RSKp70_RPS6KB1_ST	O00418	EEF2K	P23443	RPS6KB1	S71	R68W	68	Missense	distal	-3	no	34.356	19.340	EPSD	TCGA	24.279	Loss
AGC_RSK_RSKp70_RPS6KB1_ST	O00418	EEF2K	P23443	RPS6KB1	S71	S74C	74	Missense	distal	3	no	34.356	31.117	EPSD	TCGA;ICGC;COSMIC	24.279	Down-regulation
AGC_RSK_RSKp70_RPS6KB1_ST	O00418	EEF2K	P23443	RPS6KB1	S366	S366F	366	Missense	central	0	yes	37.526	0.000	PhosphoSitePlus	TCGA;ICGC;COSMIC	24.279	Loss
AGC_RSK_RSKp70_RPS6KB1_ST	O00418	EEF2K	P23443	RPS6KB1	S366	S366C	366	Missense	central	0	yes	37.526	0.000	PhosphoSitePlus	TCGA;ICGC;COSMIC	24.279	Loss
AGC_RSK_RSKp70_RPS6KB1_ST	O00418	EEF2K	P23443	RPS6KB1	S366	P371S	371	Missense	distal	5	no	37.526	39.460	PhosphoSitePlus	TCGA;ICGC;COSMIC	24.279	Up-regulation
AGC_RSK_RSKp70_RPS6KB1_ST	O00418	EEF2K	P23443	RPS6KB1	S368	S366F	366	Missense	proximal	-2	no	22.424	24.290	EPSD	TCGA;ICGC;COSMIC	24.279	Gain
AGC_RSK_RSKp70_RPS6KB1_ST	O00418	EEF2K	P23443	RPS6KB1	S368	S366C	366	Missense	proximal	-2	no	22.424	24.663	EPSD	TCGA;ICGC;COSMIC	24.279	Gain
AGC_RSK_RSKp70_RPS6KB1_ST	O00418	EEF2K	P23443	RPS6KB1	S368	P371S	371	Missense	distal	3	no	22.424	24.963	EPSD	TCGA;ICGC;COSMIC	24.279	Gain
AGC_RSK_RSKp70_RPS6KB1_ST	O00418	EEF2K	P23443	RPS6KB1	S396	A400V	400	Missense	distal	4	no	24.361	23.651	EPSD	TCGA;ICGC;COSMIC	24.279	Loss
AGC_RSK_RSKp70_RPS6KB1_ST	O00418	EEF2K	P23443	RPS6KB1	S396	S396F	396	Missense	central	0	yes	24.361	0.000	EPSD	TCGA;ICGC;COSMIC	24.279	Loss
AGC_RSK_RSKp70_RPS6KB1_ST	O00418	EEF2K	P23443	RPS6KB1	S396	S392F	392	Missense	distal	-4	no	24.361	21.734	EPSD	TCGA;ICGC;COSMIC	24.279	Loss
AGC_RSK_RSKp70_RPS6KB1_ST	O00418	EEF2K	P23443	RPS6KB1	S396	D391N	391	Missense	distal	-5	no	24.361	26.201	EPSD	TCGA;ICGC	24.279	Up-regulation
AGC_RSK_RSKp70_RPS6KB1_ST	O00418	EEF2K	P23443	RPS6KB1	S404	A400V	400	Missense	distal	-4	no	28.363	27.375	EPSD	TCGA;ICGC;COSMIC	24.279	Down-regulation
AGC_RSK_RSKp70_RPS6KB1_ST	O00418	EEF2K	P23443	RPS6KB1	S416	M421V	421	Missense	distal	5	no	25.562	25.544	EPSD	TCGA;ICGC;COSMIC	24.279	Down-regulation
AGC_RSK_RSKp70_RPS6KB1_ST	O00418	EEF2K	P23443	RPS6KB1	S416	P413S	413	Missense	distal	-3	no	25.562	28.699	EPSD	TCGA;ICGC;COSMIC	24.279	Up-regulation
AGC_RSK_RSKp70_RPS6KB1_ST	O00418	EEF2K	P23443	RPS6KB1	S435	N431Y	431	Missense	distal	-4	no	26.043	26.458	EPSD	TCGA;ICGC;COSMIC	24.279	Up-regulation
AGC_RSK_RSKp70_RPS6KB1_ST	O00418	EEF2K	P23443	RPS6KB1	S438	N431Y	431	Missense	distal	-7	no	28.507	28.703	EPSD	TCGA;ICGC;COSMIC	24.279	Up-regulation
AGC_RSK_RSKp70_RPS6KB1_ST	O00418	EEF2K	P23443	RPS6KB1	S470	E472G	472	Missense	proximal	2	no	27.506	28.509	EPSD	TCGA;ICGC;COSMIC	24.279	Up-regulation
AGC_RSK_RSKp70_RPS6KB1_ST	O00418	EEF2K	P23443	RPS6KB1	S470	E472K	472	Missense	proximal	2	no	27.506	29.164	EPSD	TCGA;ICGC	24.279	Up-regulation
AGC_RSK_RSKp70_RPS6KB1_ST	P03372	ESR1	P23443	RPS6KB1	S118	P113S	113	Missense	distal	-5	no	25.450	28.388	EPSD	TCGA;ICGC;COSMIC	24.279	Up-regulation
AGC_RSK_RSKp70_RPS6KB1_ST	P03372	ESR1	P23443	RPS6KB1	S154	P152T	152	Missense	proximal	-2	no	24.680	23.824	EPSD	TCGA;ICGC;COSMIC	24.279	Loss
AGC_RSK_RSKp70_RPS6KB1_ST	P03372	ESR1	P23443	RPS6KB1	S167	A166S	166	Missense	proximal	-1	no	39.842	39.737	PhosphoSitePlus	TCGA;ICGC;COSMIC	24.279	Down-regulation
AGC_RSK_RSKp70_RPS6KB1_ST	P03372	ESR1	P23443	RPS6KB1	S167	K171M	171	Missense	distal	4	no	39.842	39.430	PhosphoSitePlus	TCGA;ICGC;COSMIC	24.279	Down-regulation
AGC_RSK_RSKp70_RPS6KB1_ST	P03372	ESR1	P23443	RPS6KB1	S201	H196R	196	Missense	distal	-5	no	22.406	25.260	EPSD	TCGA;ICGC;COSMIC	24.279	Gain
AGC_RSK_RSKp70_RPS6KB1_ST	P03372	ESR1	P23443	RPS6KB1	S236	K235N	235	Missense	proximal	-1	no	28.484	28.488	EPSD	TCGA;ICGC;COSMIC	24.279	Up-regulation
AGC_RSK_RSKp70_RPS6KB1_ST	P03372	ESR1	P23443	RPS6KB1	S236	A239S	239	Missense	distal	3	no	28.484	30.933	EPSD	TCGA;ICGC;COSMIC	24.279	Up-regulation
AGC_RSK_RSKp70_RPS6KB1_ST	P03372	ESR1	P23443	RPS6KB1	S236	R243H	243	Missense	distal	7	no	28.484	28.371	EPSD	TCGA;ICGC;COSMIC	24.279	Down-regulation
AGC_RSK_RSKp70_RPS6KB1_ST	P03372	ESR1	P23443	RPS6KB1	S236	R243C	243	Missense	distal	7	no	28.484	27.483	EPSD	TCGA;ICGC;COSMIC	24.279	Down-regulation
AGC_RSK_RSKp70_RPS6KB1_ST	P03372	ESR1	P23443	RPS6KB1	S236	C240Y	240	Missense	distal	4	no	28.484	28.945	EPSD	TCGA;ICGC;COSMIC	24.279	Up-regulation
AGC_RSK_RSKp70_RPS6KB1_ST	P03372	ESR1	P23443	RPS6KB1	S282	G278C	278	Missense	distal	-4	no	25.502	26.099	EPSD	TCGA;ICGC;COSMIC	24.279	Up-regulation
AGC_RSK_RSKp70_RPS6KB1_ST	P03372	ESR1	P23443	RPS6KB1	S282	M286T	286	Missense	distal	4	no	25.502	25.449	EPSD	TCGA;ICGC;COSMIC	24.279	Down-regulation
AGC_RSK_RSKp70_RPS6KB1_ST	P03372	ESR1	P23443	RPS6KB1	S305	A307S	307	Missense	proximal	2	no	23.087	25.949	EPSD	TCGA;ICGC;COSMIC	24.279	Gain
AGC_RSK_RSKp70_RPS6KB1_ST	P03372	ESR1	P23443	RPS6KB1	S341	P336T	336	Missense	distal	-5	no	27.403	28.276	EPSD	TCGA;ICGC;COSMIC	24.279	Up-regulation
AGC_RSK_RSKp70_RPS6KB1_ST	P03372	ESR1	P23443	RPS6KB1	S341	G344D	344	Missense	distal	3	no	27.403	30.040	EPSD	TCGA;ICGC;COSMIC	24.279	Up-regulation
AGC_RSK_RSKp70_RPS6KB1_ST	P03372	ESR1	P23443	RPS6KB1	S559	T563M	563	Missense	distal	4	no	25.754	25.808	EPSD	TCGA;ICGC;COSMIC	24.279	Up-regulation
AGC_RSK_RSKp70_RPS6KB1_ST	P03372	ESR1	P23443	RPS6KB1	S559	R555C	555	Missense	distal	-4	no	25.754	24.361	EPSD	TCGA;ICGC;COSMIC	24.279	Down-regulation
AGC_RSK_RSKp70_RPS6KB1_ST	P03372	ESR1	P23443	RPS6KB1	S559	R555H	555	Missense	distal	-4	no	25.754	25.299	EPSD	TCGA;ICGC;COSMIC;GDSC	24.279	Down-regulation
AGC_RSK_RSKp70_RPS6KB1_ST	Q05195	MXD1	P23443	RPS6KB1	S32	Y30H	30	Missense	proximal	-2	no	24.498	24.130	EPSD	TCGA;ICGC;COSMIC	24.279	Loss
AGC_RSK_RSKp70_RPS6KB1_ST	Q05195	MXD1	P23443	RPS6KB1	S32	N38S	38	Missense	distal	6	no	24.498	25.955	EPSD	TCGA;ICGC;COSMIC	24.279	Up-regulation
AGC_RSK_RSKp70_RPS6KB1_ST	Q05195	MXD1	P23443	RPS6KB1	S89	T94M	94	Missense	distal	5	no	25.487	23.998	EPSD	TCGA;COSMIC	24.279	Loss
AGC_RSK_RSKp70_RPS6KB1_ST	Q05195	MXD1	P23443	RPS6KB1	T93	T94M	94	Missense	proximal	1	no	25.303	24.770	EPSD	TCGA;COSMIC	24.279	Down-regulation
AGC_RSK_RSKp70_RPS6KB1_ST	Q05195	MXD1	P23443	RPS6KB1	T94	T94M	94	Missense	central	0	yes	29.109	0.000	EPSD	TCGA;COSMIC	24.279	Loss
AGC_RSK_RSKp70_RPS6KB1_ST	Q05195	MXD1	P23443	RPS6KB1	S96	T94M	94	Missense	proximal	-2	no	24.803	24.435	EPSD	TCGA;COSMIC	24.279	Down-regulation
AGC_RSK_RSKp70_RPS6KB1_ST	Q05195	MXD1	P23443	RPS6KB1	S145	I138T	138	Missense	distal	-7	no	38.496	38.371	PhosphoSitePlus	TCGA;COSMIC	24.279	Down-regulation
AGC_RSK_RSKp70_RPS6KB1_ST	Q05195	MXD1	P23443	RPS6KB1	S145	M143I	143	Missense	proximal	-2	no	38.496	38.877	PhosphoSitePlus	TCGA;COSMIC	24.279	Up-regulation
AGC_RSK_RSKp70_RPS6KB1_ST	Q05195	MXD1	P23443	RPS6KB1	S194	L195F	195	Missense	proximal	1	no	27.511	27.955	EPSD	TCGA;COSMIC	24.279	Up-regulation
AGC_RSK_RSKp70_RPS6KB1_ST	O94763	URI1	P23443	RPS6KB1	T241	S243F	243	Missense	proximal	2	no	25.106	19.907	EPSD	TCGA;ICGC;COSMIC	24.279	Loss
AGC_RSK_RSKp70_RPS6KB1_ST	O94763	URI1	P23443	RPS6KB1	T350	T354I	354	Missense	distal	4	no	37.604	37.165	EPSD	TCGA;COSMIC	24.279	Down-regulation
AGC_RSK_RSKp70_RPS6KB1_ST	O94763	URI1	P23443	RPS6KB1	T350	K352N	352	Missense	proximal	2	no	37.604	35.254	EPSD	TCGA;ICGC;COSMIC	24.279	Down-regulation
AGC_RSK_RSKp70_RPS6KB1_ST	O94763	URI1	P23443	RPS6KB1	T350	R347Q	347	Missense	distal	-3	no	37.604	18.548	EPSD	TCGA;ICGC	24.279	Loss
AGC_RSK_RSKp70_RPS6KB1_ST	O94763	URI1	P23443	RPS6KB1	S359	T354I	354	Missense	distal	-5	no	25.048	21.485	EPSD	TCGA;COSMIC	24.279	Loss
AGC_RSK_RSKp70_RPS6KB1_ST	O94763	URI1	P23443	RPS6KB1	S359	K352N	352	Missense	distal	-7	no	25.048	25.068	EPSD	TCGA;ICGC;COSMIC	24.279	Up-regulation
AGC_RSK_RSKp70_RPS6KB1_ST	O94763	URI1	P23443	RPS6KB1	S372	S378C	378	Missense	distal	6	no	47.363	46.359	PhosphoSitePlus	TCGA;ICGC;COSMIC	24.279	Down-regulation
AGC_RSK_RSKp70_RPS6KB1_ST	O94763	URI1	P23443	RPS6KB1	S372	R369Q	369	Missense	distal	-3	no	47.363	28.307	PhosphoSitePlus	TCGA;ICGC;COSMIC	24.279	Down-regulation
AGC_RSK_RSKp70_RPS6KB1_ST	O94763	URI1	P23443	RPS6KB1	S372	H377Y	377	Missense	distal	5	no	47.363	44.995	PhosphoSitePlus	TCGA;ICGC;COSMIC	24.279	Down-regulation
AGC_RSK_RSKp70_RPS6KB1_ST	O94763	URI1	P23443	RPS6KB1	S372	R367C	367	Missense	distal	-5	no	47.363	38.130	PhosphoSitePlus	TCGA;ICGC;COSMIC	24.279	Down-regulation
AGC_RSK_RSKp70_RPS6KB1_ST	O94763	URI1	P23443	RPS6KB1	T373	S378C	378	Missense	distal	5	no	24.961	21.564	EPSD	TCGA;ICGC;COSMIC	24.279	Loss
AGC_RSK_RSKp70_RPS6KB1_ST	O94763	URI1	P23443	RPS6KB1	T373	R369Q	369	Missense	distal	-4	no	24.961	22.941	EPSD	TCGA;ICGC;COSMIC	24.279	Loss
AGC_RSK_RSKp70_RPS6KB1_ST	O94763	URI1	P23443	RPS6KB1	T373	H377Y	377	Missense	distal	4	no	24.961	24.711	EPSD	TCGA;ICGC;COSMIC	24.279	Down-regulation
AGC_RSK_RSKp70_RPS6KB1_ST	O94763	URI1	P23443	RPS6KB1	T373	R367C	367	Missense	distal	-6	no	24.961	25.001	EPSD	TCGA;ICGC;COSMIC	24.279	Up-regulation
AGC_RSK_RSKp70_RPS6KB1_ST	O94763	URI1	P23443	RPS6KB1	S418	R413Q	413	Missense	distal	-5	no	33.719	21.744	EPSD	TCGA;COSMIC	24.279	Loss
AGC_RSK_RSKp70_RPS6KB1_ST	O94763	URI1	P23443	RPS6KB1	S418	E416D	416	Missense	proximal	-2	no	33.719	34.101	EPSD	TCGA;ICGC;COSMIC	24.279	Up-regulation
AGC_RSK_RSKp70_RPS6KB1_ST	O94763	URI1	P23443	RPS6KB1	S418	D422N	422	Missense	distal	4	no	33.719	33.733	EPSD	TCGA;ICGC	24.279	Up-regulation
AGC_RSK_RSKp70_RPS6KB1_ST	O94763	URI1	P23443	RPS6KB1	S421	E416D	416	Missense	distal	-5	no	25.761	21.871	EPSD	TCGA;ICGC;COSMIC	24.279	Loss
AGC_RSK_RSKp70_RPS6KB1_ST	O94763	URI1	P23443	RPS6KB1	S421	D422N	422	Missense	proximal	1	no	25.761	24.767	EPSD	TCGA;ICGC	24.279	Down-regulation
AGC_RSK_RSKp70_RPS6KB1_ST	O94763	URI1	P23443	RPS6KB1	S442	R435Q	435	Missense	distal	-7	no	27.609	27.679	EPSD	TCGA;ICGC;COSMIC	24.279	Up-regulation
AGC_RSK_RSKp70_RPS6KB1_ST	O94763	URI1	P23443	RPS6KB1	S442	L438W	438	Missense	distal	-4	no	27.609	25.625	EPSD	TCGA;ICGC;COSMIC	24.279	Down-regulation
AGC_RSK_RSKp70_RPS6KB1_ST	O94763	URI1	P23443	RPS6KB1	S442	E445K	445	Missense	distal	3	no	27.609	26.835	EPSD	TCGA;ICGC	24.279	Down-regulation
AGC_RSK_RSKp70_RPS6KB1_ST	O94763	URI1	P23443	RPS6KB1	S449	E445K	445	Missense	distal	-4	no	23.753	25.144	EPSD	TCGA;ICGC	24.279	Gain
AGC_RSK_RSKp70_RPS6KB1_ST	P27708	CAD	P23443	RPS6KB1	S1069	L1071F	1071	Missense	proximal	2	no	25.150	21.126	EPSD	TCGA	24.279	Loss
AGC_RSK_RSKp70_RPS6KB1_ST	P27708	CAD	P23443	RPS6KB1	S1118	A1114T	1114	Missense	distal	-4	no	25.410	25.641	EPSD	TCGA	24.279	Up-regulation
AGC_RSK_RSKp70_RPS6KB1_ST	P27708	CAD	P23443	RPS6KB1	S1118	V1123L	1123	Missense	distal	5	no	25.410	27.092	EPSD	TCGA;COSMIC	24.279	Up-regulation
AGC_RSK_RSKp70_RPS6KB1_ST	P27708	CAD	P23443	RPS6KB1	S1118	P1122L	1122	Missense	distal	4	no	25.410	25.897	EPSD	TCGA;COSMIC	24.279	Up-regulation
AGC_RSK_RSKp70_RPS6KB1_ST	P27708	CAD	P23443	RPS6KB1	S1337	R1333W	1333	Missense	distal	-4	no	26.498	24.817	EPSD	TCGA;COSMIC	24.279	Down-regulation
AGC_RSK_RSKp70_RPS6KB1_ST	P27708	CAD	P23443	RPS6KB1	S1406	G1401A	1401	Missense	distal	-5	no	27.501	27.003	EPSD	TCGA;COSMIC	24.279	Down-regulation
AGC_RSK_RSKp70_RPS6KB1_ST	P27708	CAD	P23443	RPS6KB1	S1406	Y1413H	1413	Missense	distal	7	no	27.501	27.553	EPSD	TCGA;COSMIC	24.279	Up-regulation
AGC_RSK_RSKp70_RPS6KB1_ST	P27708	CAD	P23443	RPS6KB1	S1406	L1405F	1405	Missense	proximal	-1	no	27.501	27.571	EPSD	TCGA;COSMIC	24.279	Up-regulation
AGC_RSK_RSKp70_RPS6KB1_ST	P27708	CAD	P23443	RPS6KB1	S1406	G1401V	1401	Missense	distal	-5	no	27.501	25.962	EPSD	TCGA;COSMIC	24.279	Down-regulation
AGC_RSK_RSKp70_RPS6KB1_ST	P27708	CAD	P23443	RPS6KB1	S1407	Y1413H	1413	Missense	distal	6	no	23.124	24.421	EPSD	TCGA;COSMIC	24.279	Gain
AGC_RSK_RSKp70_RPS6KB1_ST	P27708	CAD	P23443	RPS6KB1	S1407	L1405F	1405	Missense	proximal	-2	no	23.124	24.849	EPSD	TCGA;COSMIC	24.279	Gain
AGC_RSK_RSKp70_RPS6KB1_ST	P27708	CAD	P23443	RPS6KB1	S1423	I1430M	1430	Missense	distal	7	no	27.176	27.511	EPSD	TCGA;COSMIC	24.279	Up-regulation
AGC_RSK_RSKp70_RPS6KB1_ST	P27708	CAD	P23443	RPS6KB1	S1423	I1428V	1428	Missense	distal	5	no	27.176	27.875	EPSD	TCGA	24.279	Up-regulation
AGC_RSK_RSKp70_RPS6KB1_ST	P27708	CAD	P23443	RPS6KB1	S1423	P1425S	1425	Missense	proximal	2	no	27.176	29.528	EPSD	TCGA;COSMIC	24.279	Up-regulation
AGC_RSK_RSKp70_RPS6KB1_ST	P27708	CAD	P23443	RPS6KB1	S1423	R1416Q	1416	Missense	distal	-7	no	27.176	27.246	EPSD	TCGA	24.279	Up-regulation
AGC_RSK_RSKp70_RPS6KB1_ST	P27708	CAD	P23443	RPS6KB1	S1458	P1465L	1465	Missense	distal	7	no	30.296	30.254	EPSD	TCGA;COSMIC	24.279	Down-regulation
AGC_RSK_RSKp70_RPS6KB1_ST	P27708	CAD	P23443	RPS6KB1	S1646	R1652H	1652	Missense	distal	6	no	24.007	24.402	EPSD	TCGA;COSMIC	24.279	Gain
AGC_RSK_RSKp70_RPS6KB1_ST	P27708	CAD	P23443	RPS6KB1	S1859	E1866K	1866	Missense	distal	7	no	36.039	36.066	PhosphoSitePlus	TCGA;COSMIC	24.279	Up-regulation
AGC_RSK_RSKp70_RPS6KB1_ST	P27708	CAD	P23443	RPS6KB1	S1859	P1852Q	1852	Missense	distal	-7	no	36.039	35.940	PhosphoSitePlus	TCGA;COSMIC	24.279	Down-regulation
AGC_RSK_RSKp70_RPS6KB1_ST	P27708	CAD	P23443	RPS6KB1	S1900	P1901H	1901	Missense	proximal	1	no	28.623	27.989	EPSD	TCGA;COSMIC	24.279	Down-regulation
AGC_RSK_RSKp70_RPS6KB1_ST	P27708	CAD	P23443	RPS6KB1	S1900	A1899T	1899	Missense	proximal	-1	no	28.623	28.546	EPSD	TCGA;COSMIC	24.279	Down-regulation
AGC_RSK_RSKp70_RPS6KB1_ST	P27708	CAD	P23443	RPS6KB1	S2154	E2159K	2159	Missense	distal	5	no	32.412	32.637	EPSD	TCGA	24.279	Up-regulation
AGC_RSK_RSKp70_RPS6KB1_ST	P27708	CAD	P23443	RPS6KB1	S2154	A2160D	2160	Missense	distal	6	no	32.412	32.215	EPSD	TCGA	24.279	Down-regulation
AGC_RSK_RSKp70_RPS6KB1_ST	Q09161	NCBP1	P23443	RPS6KB1	S434	D432H	432	Missense	proximal	-2	no	28.061	26.966	EPSD	TCGA;ICGC;COSMIC	24.279	Down-regulation
AGC_RSK_RSKp70_RPS6KB1_ST	Q9GZT9	EGLN1	P23443	RPS6KB1	T185	A190T	190	Missense	distal	5	no	32.445	33.288	EPSD	TCGA;ICGC	24.279	Up-regulation
AGC_RSK_RSKp70_RPS6KB1_ST	P78371	CCT2	P23443	RPS6KB1	S28	A34T	34	Missense	distal	6	no	24.842	26.030	EPSD	TCGA;ICGC;COSMIC	24.279	Up-regulation
AGC_RSK_RSKp70_RPS6KB1_ST	P78371	CCT2	P23443	RPS6KB1	S55	D58N	58	Missense	distal	3	no	23.943	24.462	EPSD	TCGA;ICGC;COSMIC	24.279	Gain
AGC_RSK_RSKp70_RPS6KB1_ST	P78371	CCT2	P23443	RPS6KB1	S60	D58N	58	Missense	proximal	-2	no	30.634	30.619	EPSD	TCGA;ICGC;COSMIC	24.279	Down-regulation
AGC_RSK_RSKp70_RPS6KB1_ST	P78371	CCT2	P23443	RPS6KB1	S115	I121S	121	Missense	distal	6	no	23.954	25.077	EPSD	TCGA;ICGC;COSMIC	24.279	Gain
AGC_RSK_RSKp70_RPS6KB1_ST	P78371	CCT2	P23443	RPS6KB1	S143	S150F	150	Missense	distal	7	no	31.119	29.239	EPSD	TCGA;ICGC;COSMIC	24.279	Down-regulation
AGC_RSK_RSKp70_RPS6KB1_ST	P78371	CCT2	P23443	RPS6KB1	S143	H148L	148	Missense	distal	5	no	31.119	32.006	EPSD	TCGA;ICGC	24.279	Up-regulation
AGC_RSK_RSKp70_RPS6KB1_ST	P78371	CCT2	P23443	RPS6KB1	S208	G207E	207	Missense	proximal	-1	no	26.016	25.937	EPSD	TCGA;ICGC;COSMIC	24.279	Down-regulation
AGC_RSK_RSKp70_RPS6KB1_ST	P78371	CCT2	P23443	RPS6KB1	S212	G207E	207	Missense	distal	-5	no	23.905	26.550	EPSD	TCGA;ICGC;COSMIC	24.279	Gain
AGC_RSK_RSKp70_RPS6KB1_ST	P78371	CCT2	P23443	RPS6KB1	S260	E266Q	266	Missense	distal	6	no	38.551	38.488	PhosphoSitePlus	TCGA;ICGC;COSMIC	24.279	Down-regulation
AGC_RSK_RSKp70_RPS6KB1_ST	O60331	PIP5K1C	P23443	RPS6KB1	T69	K72R	72	Missense	distal	3	no	26.322	25.294	EPSD	TCGA;ICGC;COSMIC	24.279	Down-regulation
AGC_RSK_RSKp70_RPS6KB1_ST	O60331	PIP5K1C	P23443	RPS6KB1	T69	G62C	62	Missense	distal	-7	no	26.322	26.310	EPSD	TCGA;ICGC;COSMIC	24.279	Down-regulation
AGC_RSK_RSKp70_RPS6KB1_ST	O60331	PIP5K1C	P23443	RPS6KB1	T69	G67C	67	Missense	proximal	-2	no	26.322	28.783	EPSD	TCGA;ICGC;COSMIC	24.279	Up-regulation
AGC_RSK_RSKp70_RPS6KB1_ST	O60331	PIP5K1C	P23443	RPS6KB1	S448	P454A	454	Missense	distal	6	no	33.501	33.356	EPSD	TCGA;ICGC;COSMIC	24.279	Down-regulation
AGC_RSK_RSKp70_RPS6KB1_ST	O60331	PIP5K1C	P23443	RPS6KB1	S448	R445W	445	Missense	distal	-3	no	33.501	18.486	EPSD	TCGA;ICGC;COSMIC	24.279	Loss
AGC_RSK_RSKp70_RPS6KB1_ST	O60331	PIP5K1C	P23443	RPS6KB1	S449	P454A	454	Missense	distal	5	no	25.884	26.091	EPSD	TCGA;ICGC;COSMIC	24.279	Up-regulation
AGC_RSK_RSKp70_RPS6KB1_ST	O60331	PIP5K1C	P23443	RPS6KB1	S449	R445W	445	Missense	distal	-4	no	25.884	24.204	EPSD	TCGA;ICGC;COSMIC	24.279	Loss
AGC_RSK_RSKp70_RPS6KB1_ST	O60331	PIP5K1C	P23443	RPS6KB1	S453	P454A	454	Missense	proximal	1	no	36.855	35.457	EPSD	TCGA;ICGC;COSMIC	24.279	Down-regulation
AGC_RSK_RSKp70_RPS6KB1_ST	O60331	PIP5K1C	P23443	RPS6KB1	S453	R459C	459	Missense	distal	6	no	36.855	36.428	EPSD	TCGA;ICGC;COSMIC;CCLE	24.279	Down-regulation
AGC_RSK_RSKp70_RPS6KB1_ST	O60331	PIP5K1C	P23443	RPS6KB1	S496	R492W	492	Missense	distal	-4	no	27.598	25.918	EPSD	TCGA;ICGC;COSMIC	24.279	Down-regulation
AGC_RSK_RSKp70_RPS6KB1_ST	O60331	PIP5K1C	P23443	RPS6KB1	S496	T499M	499	Missense	distal	3	no	27.598	28.670	EPSD	TCGA;ICGC;COSMIC;GDSC;CCLE	24.279	Up-regulation
AGC_RSK_RSKp70_RPS6KB1_ST	O60331	PIP5K1C	P23443	RPS6KB1	S523	A525T	525	Missense	proximal	2	no	26.853	28.817	EPSD	TCGA;ICGC	24.279	Up-regulation
AGC_RSK_RSKp70_RPS6KB1_ST	O60331	PIP5K1C	P23443	RPS6KB1	S523	S530F	530	Missense	distal	7	no	26.853	24.972	EPSD	TCGA;ICGC;COSMIC	24.279	Down-regulation
AGC_RSK_RSKp70_RPS6KB1_ST	O60331	PIP5K1C	P23443	RPS6KB1	S523	T526M	526	Missense	distal	3	no	26.853	27.925	EPSD	TCGA;ICGC	24.279	Up-regulation
AGC_RSK_RSKp70_RPS6KB1_ST	O60331	PIP5K1C	P23443	RPS6KB1	S541	S541L	541	Missense	central	0	yes	24.868	0.000	EPSD	TCGA;ICGC;COSMIC	24.279	Loss
AGC_RSK_RSKp70_RPS6KB1_ST	O60331	PIP5K1C	P23443	RPS6KB1	S541	S534F	534	Missense	distal	-7	no	24.868	25.229	EPSD	TCGA;ICGC;COSMIC	24.279	Up-regulation
AGC_RSK_RSKp70_RPS6KB1_ST	O60331	PIP5K1C	P23443	RPS6KB1	S541	R548W	548	Missense	distal	7	no	24.868	24.316	EPSD	TCGA;ICGC;COSMIC	24.279	Down-regulation
AGC_RSK_RSKp70_RPS6KB1_ST	O60331	PIP5K1C	P23443	RPS6KB1	S541	R548Q	548	Missense	distal	7	no	24.868	25.451	EPSD	TCGA;ICGC	24.279	Up-regulation
AGC_RSK_RSKp70_RPS6KB1_ST	O60331	PIP5K1C	P23443	RPS6KB1	S541	P540S	540	Missense	proximal	-1	no	24.868	24.771	EPSD	TCGA;ICGC;COSMIC	24.279	Down-regulation
AGC_RSK_RSKp70_RPS6KB1_ST	O60331	PIP5K1C	P23443	RPS6KB1	S541	R538Q	538	Missense	distal	-3	no	24.868	5.812	EPSD	TCGA;ICGC;COSMIC	24.279	Loss
AGC_RSK_RSKp70_RPS6KB1_ST	O60331	PIP5K1C	P23443	RPS6KB1	S541	R538W	538	Missense	distal	-3	no	24.868	9.853	EPSD	TCGA;ICGC	24.279	Loss
AGC_RSK_RSKp70_RPS6KB1_ST	O60331	PIP5K1C	P23443	RPS6KB1	T553	R551Q	551	Missense	proximal	-2	no	35.564	36.366	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	24.279	Up-regulation
AGC_RSK_RSKp70_RPS6KB1_ST	O60331	PIP5K1C	P23443	RPS6KB1	T553	R548W	548	Missense	distal	-5	no	35.564	23.600	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	24.279	Loss
AGC_RSK_RSKp70_RPS6KB1_ST	O60331	PIP5K1C	P23443	RPS6KB1	T553	R548Q	548	Missense	distal	-5	no	35.564	23.589	EPSD;PhosphoSitePlus	TCGA;ICGC	24.279	Loss
AGC_RSK_RSKp70_RPS6KB1_ST	O60331	PIP5K1C	P23443	RPS6KB1	T553	R551W	551	Missense	proximal	-2	no	35.564	36.481	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	24.279	Up-regulation
AGC_RSK_RSKp70_RPS6KB1_ST	O60331	PIP5K1C	P23443	RPS6KB1	S555	R551Q	551	Missense	distal	-4	no	37.679	35.658	PhosphoSitePlus;EPSD	TCGA;ICGC;COSMIC	24.279	Down-regulation
AGC_RSK_RSKp70_RPS6KB1_ST	O60331	PIP5K1C	P23443	RPS6KB1	S555	R548W	548	Missense	distal	-7	no	37.679	37.883	PhosphoSitePlus;EPSD	TCGA;ICGC;COSMIC	24.279	Up-regulation
AGC_RSK_RSKp70_RPS6KB1_ST	O60331	PIP5K1C	P23443	RPS6KB1	S555	R548Q	548	Missense	distal	-7	no	37.679	37.749	PhosphoSitePlus;EPSD	TCGA;ICGC	24.279	Up-regulation
AGC_RSK_RSKp70_RPS6KB1_ST	O60331	PIP5K1C	P23443	RPS6KB1	S555	R561S	561	Missense	distal	6	no	37.679	38.256	PhosphoSitePlus;EPSD	TCGA;ICGC;COSMIC	24.279	Up-regulation
AGC_RSK_RSKp70_RPS6KB1_ST	O60331	PIP5K1C	P23443	RPS6KB1	S555	R561T	561	Missense	distal	6	no	37.679	38.325	PhosphoSitePlus;EPSD	TCGA;ICGC;COSMIC	24.279	Up-regulation
AGC_RSK_RSKp70_RPS6KB1_ST	O60331	PIP5K1C	P23443	RPS6KB1	S555	R551W	551	Missense	distal	-4	no	37.679	35.999	PhosphoSitePlus;EPSD	TCGA;ICGC;COSMIC	24.279	Down-regulation
AGC_RSK_RSKp70_RPS6KB1_ST	P08151	GLI1	P23443	RPS6KB1	S84	I85M	85	Missense	proximal	1	no	37.289	36.784	PhosphoSitePlus	TCGA;COSMIC	24.279	Down-regulation
AGC_RSK_RSKp70_RPS6KB1_ST	P08151	GLI1	P23443	RPS6KB1	S84	R81L	81	Missense	distal	-3	no	37.289	27.622	PhosphoSitePlus	TCGA;COSMIC	24.279	Down-regulation
AGC_RSK_RSKp70_RPS6KB1_ST	P08151	GLI1	P23443	RPS6KB1	S84	S89L	89	Missense	distal	5	no	37.289	36.579	PhosphoSitePlus	TCGA;COSMIC	24.279	Down-regulation
AGC_RSK_RSKp70_RPS6KB1_ST	P08151	GLI1	P23443	RPS6KB1	S84	S84P	84	Missense	central	0	yes	37.289	0.000	PhosphoSitePlus	TCGA;COSMIC	24.279	Loss
AGC_RSK_RSKp70_RPS6KB1_ST	P08151	GLI1	P23443	RPS6KB1	S84	R81W	81	Missense	distal	-3	no	37.289	22.274	PhosphoSitePlus	TCGA;COSMIC	24.279	Loss
AGC_RSK_RSKp70_RPS6KB1_ST	P08151	GLI1	P23443	RPS6KB1	S84	R81Q	81	Missense	distal	-3	no	37.289	18.233	PhosphoSitePlus	TCGA;COSMIC	24.279	Loss
AGC_RSK_RSKp70_RPS6KB1_ST	P08151	GLI1	P23443	RPS6KB1	S84	K79N	79	Missense	distal	-5	no	37.289	36.431	PhosphoSitePlus	TCGA;COSMIC	24.279	Down-regulation
AGC_RSK_RSKp70_RPS6KB1_ST	P08151	GLI1	P23443	RPS6KB1	S86	R81L	81	Missense	distal	-5	no	27.111	18.487	EPSD	TCGA;COSMIC	24.279	Loss
AGC_RSK_RSKp70_RPS6KB1_ST	P08151	GLI1	P23443	RPS6KB1	S86	S89L	89	Missense	distal	3	no	27.111	25.412	EPSD	TCGA;COSMIC	24.279	Down-regulation
AGC_RSK_RSKp70_RPS6KB1_ST	P08151	GLI1	P23443	RPS6KB1	S86	S84P	84	Missense	proximal	-2	no	27.111	29.018	EPSD	TCGA;COSMIC	24.279	Up-regulation
AGC_RSK_RSKp70_RPS6KB1_ST	P08151	GLI1	P23443	RPS6KB1	S86	R81W	81	Missense	distal	-5	no	27.111	15.148	EPSD	TCGA;COSMIC	24.279	Loss
AGC_RSK_RSKp70_RPS6KB1_ST	P08151	GLI1	P23443	RPS6KB1	S86	R81Q	81	Missense	distal	-5	no	27.111	15.136	EPSD	TCGA;COSMIC	24.279	Loss
AGC_RSK_RSKp70_RPS6KB1_ST	P08151	GLI1	P23443	RPS6KB1	S86	K79N	79	Missense	distal	-7	no	27.111	27.131	EPSD	TCGA;COSMIC	24.279	Up-regulation
AGC_RSK_RSKp70_RPS6KB1_ST	P08151	GLI1	P23443	RPS6KB1	S204	P210S	210	Missense	distal	6	no	23.400	24.375	EPSD	TCGA;COSMIC	24.279	Gain
AGC_RSK_RSKp70_RPS6KB1_ST	P08151	GLI1	P23443	RPS6KB1	T304	R309W	309	Missense	distal	5	no	26.205	24.339	EPSD	TCGA	24.279	Down-regulation
AGC_RSK_RSKp70_RPS6KB1_ST	P08151	GLI1	P23443	RPS6KB1	T304	R309Q	309	Missense	distal	5	no	26.205	26.866	EPSD	TCGA;COSMIC	24.279	Up-regulation
AGC_RSK_RSKp70_RPS6KB1_ST	P08151	GLI1	P23443	RPS6KB1	S377	S378L	378	Missense	proximal	1	no	24.273	25.377	EPSD	TCGA;COSMIC	24.279	Gain
AGC_RSK_RSKp70_RPS6KB1_ST	P08151	GLI1	P23443	RPS6KB1	S377	V383A	383	Missense	distal	6	no	24.273	24.378	EPSD	TCGA;COSMIC	24.279	Gain
AGC_RSK_RSKp70_RPS6KB1_ST	P08151	GLI1	P23443	RPS6KB1	S408	R405G	405	Missense	distal	-3	no	30.573	22.749	EPSD	TCGA;COSMIC	24.279	Loss
AGC_RSK_RSKp70_RPS6KB1_ST	P08151	GLI1	P23443	RPS6KB1	S408	R405W	405	Missense	distal	-3	no	30.573	15.558	EPSD	TCGA;COSMIC	24.279	Loss
AGC_RSK_RSKp70_RPS6KB1_ST	P08151	GLI1	P23443	RPS6KB1	S521	R515W	515	Missense	distal	-6	no	28.561	28.624	EPSD	TCGA;COSMIC	24.279	Up-regulation
AGC_RSK_RSKp70_RPS6KB1_ST	P08151	GLI1	P23443	RPS6KB1	S544	R541H	541	Missense	distal	-3	no	26.742	23.254	EPSD	TCGA;COSMIC	24.279	Loss
AGC_RSK_RSKp70_RPS6KB1_ST	P08151	GLI1	P23443	RPS6KB1	S544	E540K	540	Missense	distal	-4	no	26.742	28.133	EPSD	TCGA;COSMIC	24.279	Up-regulation
AGC_RSK_RSKp70_RPS6KB1_ST	P08151	GLI1	P23443	RPS6KB1	S544	V537A	537	Missense	distal	-7	no	26.742	26.552	EPSD	TCGA;COSMIC	24.279	Down-regulation
AGC_RSK_RSKp70_RPS6KB1_ST	P08151	GLI1	P23443	RPS6KB1	S544	S543N	543	Missense	proximal	-1	no	26.742	26.815	EPSD	TCGA;COSMIC	24.279	Up-regulation
AGC_RSK_RSKp70_RPS6KB1_ST	P08151	GLI1	P23443	RPS6KB1	S544	L539P	539	Missense	distal	-5	no	26.742	26.888	EPSD	TCGA	24.279	Up-regulation
AGC_RSK_RSKp70_RPS6KB1_ST	P08151	GLI1	P23443	RPS6KB1	S545	R541H	541	Missense	distal	-4	no	26.328	25.873	EPSD	TCGA;COSMIC	24.279	Down-regulation
AGC_RSK_RSKp70_RPS6KB1_ST	P08151	GLI1	P23443	RPS6KB1	S545	E540K	540	Missense	distal	-5	no	26.328	25.135	EPSD	TCGA;COSMIC	24.279	Down-regulation
AGC_RSK_RSKp70_RPS6KB1_ST	P08151	GLI1	P23443	RPS6KB1	S545	S543N	543	Missense	proximal	-2	no	26.328	27.983	EPSD	TCGA;COSMIC	24.279	Up-regulation
AGC_RSK_RSKp70_RPS6KB1_ST	P08151	GLI1	P23443	RPS6KB1	S545	L539P	539	Missense	distal	-6	no	26.328	26.335	EPSD	TCGA	24.279	Up-regulation
AGC_RSK_RSKp70_RPS6KB1_ST	P08151	GLI1	P23443	RPS6KB1	S934	V936A	936	Missense	proximal	2	no	26.629	27.464	EPSD	TCGA;COSMIC	24.279	Up-regulation
AGC_RSK_RSKp70_RPS6KB1_ST	P08151	GLI1	P23443	RPS6KB1	S934	L931M	931	Missense	distal	-3	no	26.629	30.797	EPSD	TCGA;COSMIC	24.279	Up-regulation
AGC_RSK_RSKp70_RPS6KB1_ST	P08151	GLI1	P23443	RPS6KB1	S934	R940H	940	Missense	distal	6	no	26.629	27.024	EPSD	TCGA;GDSC;CCLE	24.279	Up-regulation
AGC_RSK_RSKp70_RPS6KB1_ST	Q6R327	RICTOR	P23443	RPS6KB1	S21	R18L	18	Missense	distal	-3	no	34.352	24.685	EPSD	TCGA;ICGC;COSMIC	24.279	Down-regulation
AGC_RSK_RSKp70_RPS6KB1_ST	Q6R327	RICTOR	P23443	RPS6KB1	S35	D36N	36	Missense	proximal	1	no	31.100	30.106	EPSD	TCGA;ICGC;COSMIC	24.279	Down-regulation
AGC_RSK_RSKp70_RPS6KB1_ST	Q6R327	RICTOR	P23443	RPS6KB1	S35	L42F	42	Missense	distal	7	no	31.100	29.736	EPSD	TCGA;ICGC;COSMIC	24.279	Down-regulation
AGC_RSK_RSKp70_RPS6KB1_ST	Q6R327	RICTOR	P23443	RPS6KB1	S35	E40K	40	Missense	distal	5	no	31.100	31.325	EPSD	TCGA;ICGC;COSMIC	24.279	Up-regulation
AGC_RSK_RSKp70_RPS6KB1_ST	Q6R327	RICTOR	P23443	RPS6KB1	S35	L30V	30	Missense	distal	-5	no	31.100	30.941	EPSD	TCGA;ICGC;COSMIC	24.279	Down-regulation
AGC_RSK_RSKp70_RPS6KB1_ST	Q6R327	RICTOR	P23443	RPS6KB1	S383	H379R	379	Missense	distal	-4	no	27.362	27.817	EPSD	TCGA;ICGC;COSMIC	24.279	Up-regulation
AGC_RSK_RSKp70_RPS6KB1_ST	Q6R327	RICTOR	P23443	RPS6KB1	S383	R380H	380	Missense	distal	-3	no	27.362	23.874	EPSD	TCGA;ICGC;COSMIC	24.279	Loss
AGC_RSK_RSKp70_RPS6KB1_ST	Q6R327	RICTOR	P23443	RPS6KB1	S704	D710N	710	Missense	distal	6	no	30.862	30.722	EPSD	TCGA;ICGC;COSMIC	24.279	Down-regulation
AGC_RSK_RSKp70_RPS6KB1_ST	Q6R327	RICTOR	P23443	RPS6KB1	S810	R807I	807	Missense	distal	-3	no	25.425	10.513	EPSD	TCGA;COSMIC	24.279	Loss
AGC_RSK_RSKp70_RPS6KB1_ST	Q6R327	RICTOR	P23443	RPS6KB1	S837	E844Q	844	Missense	distal	7	no	31.217	31.511	EPSD	TCGA;ICGC;COSMIC	24.279	Up-regulation
AGC_RSK_RSKp70_RPS6KB1_ST	Q6R327	RICTOR	P23443	RPS6KB1	S837	K830N	830	Missense	distal	-7	no	31.217	31.236	EPSD	TCGA;ICGC;COSMIC	24.279	Up-regulation
AGC_RSK_RSKp70_RPS6KB1_ST	Q6R327	RICTOR	P23443	RPS6KB1	S1035	S1042L	1042	Missense	distal	7	no	29.070	28.554	EPSD	TCGA;ICGC;COSMIC	24.279	Down-regulation
AGC_RSK_RSKp70_RPS6KB1_ST	Q6R327	RICTOR	P23443	RPS6KB1	S1035	E1038G	1038	Missense	distal	3	no	29.070	24.842	EPSD	TCGA;ICGC;COSMIC	24.279	Down-regulation
AGC_RSK_RSKp70_RPS6KB1_ST	Q6R327	RICTOR	P23443	RPS6KB1	S1037	S1042L	1042	Missense	distal	5	no	31.384	30.674	EPSD	TCGA;ICGC;COSMIC	24.279	Down-regulation
AGC_RSK_RSKp70_RPS6KB1_ST	Q6R327	RICTOR	P23443	RPS6KB1	S1037	E1038G	1038	Missense	proximal	1	no	31.384	31.314	EPSD	TCGA;ICGC;COSMIC	24.279	Down-regulation
AGC_RSK_RSKp70_RPS6KB1_ST	Q6R327	RICTOR	P23443	RPS6KB1	S1122	G1117E	1117	Missense	distal	-5	no	26.492	29.137	EPSD	TCGA;ICGC;COSMIC	24.279	Up-regulation
AGC_RSK_RSKp70_RPS6KB1_ST	Q6R327	RICTOR	P23443	RPS6KB1	S1122	L1120V	1120	Missense	proximal	-2	no	26.492	28.002	EPSD	TCGA;ICGC	24.279	Up-regulation
AGC_RSK_RSKp70_RPS6KB1_ST	Q6R327	RICTOR	P23443	RPS6KB1	T1133	T1135M	1135	Missense	proximal	2	no	38.698	37.850	EPSD	TCGA;ICGC;COSMIC	24.279	Down-regulation
AGC_RSK_RSKp70_RPS6KB1_ST	Q6R327	RICTOR	P23443	RPS6KB1	T1133	R1130Q	1130	Missense	distal	-3	no	38.698	19.642	EPSD	TCGA;ICGC;COSMIC;GDSC;CCLE	24.279	Loss
AGC_RSK_RSKp70_RPS6KB1_ST	Q6R327	RICTOR	P23443	RPS6KB1	T1135	T1135M	1135	Missense	central	0	yes	40.784	0.000	PhosphoSitePlus	TCGA;ICGC;COSMIC	24.279	Loss
AGC_RSK_RSKp70_RPS6KB1_ST	Q6R327	RICTOR	P23443	RPS6KB1	T1135	R1130Q	1130	Missense	distal	-5	no	40.784	28.809	PhosphoSitePlus	TCGA;ICGC;COSMIC;GDSC;CCLE	24.279	Down-regulation
AGC_RSK_RSKp70_RPS6KB1_ST	Q6R327	RICTOR	P23443	RPS6KB1	S1211	R1216H	1216	Missense	distal	5	no	30.296	30.597	EPSD	TCGA;ICGC;COSMIC;CCLE	24.279	Up-regulation
AGC_RSK_RSKp70_RPS6KB1_ST	Q6R327	RICTOR	P23443	RPS6KB1	S1219	T1222I	1222	Missense	distal	3	no	36.673	36.708	EPSD	TCGA;ICGC;COSMIC	24.279	Up-regulation
AGC_RSK_RSKp70_RPS6KB1_ST	Q6R327	RICTOR	P23443	RPS6KB1	S1219	R1216H	1216	Missense	distal	-3	no	36.673	33.184	EPSD	TCGA;ICGC;COSMIC;CCLE	24.279	Down-regulation
AGC_RSK_RSKp70_RPS6KB1_ST	Q6R327	RICTOR	P23443	RPS6KB1	S1227	T1222I	1222	Missense	distal	-5	no	24.370	20.806	EPSD	TCGA;ICGC;COSMIC	24.279	Loss
AGC_RSK_RSKp70_RPS6KB1_ST	Q6R327	RICTOR	P23443	RPS6KB1	S1302	R1299G	1299	Missense	distal	-3	no	29.044	21.220	EPSD	TCGA;ICGC;COSMIC	24.279	Loss
AGC_RSK_RSKp70_RPS6KB1_ST	Q6R327	RICTOR	P23443	RPS6KB1	S1302	A1305S	1305	Missense	distal	3	no	29.044	31.493	EPSD	TCGA;ICGC;COSMIC	24.279	Up-regulation
AGC_RSK_RSKp70_RPS6KB1_ST	Q6R327	RICTOR	P23443	RPS6KB1	S1307	A1305S	1305	Missense	proximal	-2	no	24.384	23.308	EPSD	TCGA;ICGC;COSMIC	24.279	Loss
AGC_RSK_RSKp70_RPS6KB1_ST	Q6R327	RICTOR	P23443	RPS6KB1	S1344	S1346C	1346	Missense	proximal	2	no	33.629	30.844	EPSD	TCGA;ICGC;COSMIC	24.279	Down-regulation
AGC_RSK_RSKp70_RPS6KB1_ST	Q6R327	RICTOR	P23443	RPS6KB1	S1346	S1346C	1346	Missense	central	0	yes	26.466	0.000	EPSD	TCGA;ICGC;COSMIC	24.279	Loss
AGC_RSK_RSKp70_RPS6KB1_ST	Q6R327	RICTOR	P23443	RPS6KB1	S1348	P1354S	1354	Missense	distal	6	no	28.252	29.227	EPSD	TCGA;ICGC;COSMIC	24.279	Up-regulation
AGC_RSK_RSKp70_RPS6KB1_ST	Q6R327	RICTOR	P23443	RPS6KB1	S1348	S1346C	1346	Missense	proximal	-2	no	28.252	30.492	EPSD	TCGA;ICGC;COSMIC	24.279	Up-regulation
AGC_RSK_RSKp70_RPS6KB1_ST	Q6R327	RICTOR	P23443	RPS6KB1	S1385	K1382Q	1382	Missense	distal	-3	no	26.309	14.873	EPSD	TCGA;ICGC	24.279	Loss
AGC_RSK_RSKp70_RPS6KB1_ST	Q6R327	RICTOR	P23443	RPS6KB1	S1385	M1381V	1381	Missense	distal	-4	no	26.309	24.289	EPSD	TCGA;ICGC;COSMIC	24.279	Down-regulation
AGC_RSK_RSKp70_RPS6KB1_ST	Q6R327	RICTOR	P23443	RPS6KB1	S1385	S1378N	1378	Missense	distal	-7	no	26.309	26.382	EPSD	TCGA;ICGC;COSMIC	24.279	Up-regulation
AGC_RSK_RSKp70_RPS6KB1_ST	Q6R327	RICTOR	P23443	RPS6KB1	S1415	G1420C	1420	Missense	distal	5	no	34.047	31.787	EPSD	TCGA;ICGC;COSMIC	24.279	Down-regulation
AGC_RSK_RSKp70_RPS6KB1_ST	Q6R327	RICTOR	P23443	RPS6KB1	S1415	A1416V	1416	Missense	proximal	1	no	34.047	35.100	EPSD	TCGA;ICGC;COSMIC	24.279	Up-regulation
AGC_RSK_RSKp70_RPS6KB1_ST	Q6R327	RICTOR	P23443	RPS6KB1	S1415	S1421P	1421	Missense	distal	6	no	34.047	33.072	EPSD	TCGA;ICGC;COSMIC	24.279	Down-regulation
AGC_RSK_RSKp70_RPS6KB1_ST	Q6R327	RICTOR	P23443	RPS6KB1	S1588	S1585L	1585	Missense	distal	-3	no	28.571	28.387	EPSD	TCGA;ICGC;COSMIC	24.279	Down-regulation
AGC_RSK_RSKp70_RPS6KB1_ST	Q6R327	RICTOR	P23443	RPS6KB1	S1588	S1588I	1588	Missense	central	0	yes	28.571	0.000	EPSD	TCGA;ICGC;COSMIC	24.279	Loss
AGC_RSK_RSKp70_RPS6KB1_ST	P23588	EIF4B	P23443	RPS6KB1	S35	P37Q	37	Missense	proximal	2	no	30.297	28.739	EPSD	TCGA;ICGC;COSMIC	24.279	Down-regulation
AGC_RSK_RSKp70_RPS6KB1_ST	P23588	EIF4B	P23443	RPS6KB1	S35	S31I	31	Missense	distal	-4	no	30.297	29.435	EPSD	TCGA;ICGC;COSMIC	24.279	Down-regulation
AGC_RSK_RSKp70_RPS6KB1_ST	P23588	EIF4B	P23443	RPS6KB1	S93	R87W	87	Missense	distal	-6	no	28.236	28.299	EPSD	TCGA;ICGC	24.279	Up-regulation
AGC_RSK_RSKp70_RPS6KB1_ST	P23588	EIF4B	P23443	RPS6KB1	S93	R89S	89	Missense	distal	-4	no	28.236	29.294	EPSD	TCGA;ICGC;COSMIC	24.279	Up-regulation
AGC_RSK_RSKp70_RPS6KB1_ST	P23588	EIF4B	P23443	RPS6KB1	S93	S93W	93	Missense	central	0	yes	28.236	0.000	EPSD	TCGA;ICGC;COSMIC	24.279	Loss
AGC_RSK_RSKp70_RPS6KB1_ST	P23588	EIF4B	P23443	RPS6KB1	S93	A98V	98	Missense	distal	5	no	28.236	27.572	EPSD	TCGA;ICGC;COSMIC	24.279	Down-regulation
AGC_RSK_RSKp70_RPS6KB1_ST	P23588	EIF4B	P23443	RPS6KB1	S131	E129K	129	Missense	proximal	-2	no	27.474	27.154	EPSD	TCGA;ICGC;COSMIC	24.279	Down-regulation
AGC_RSK_RSKp70_RPS6KB1_ST	P23588	EIF4B	P23443	RPS6KB1	S131	E134K	134	Missense	distal	3	no	27.474	26.700	EPSD	TCGA;ICGC;COSMIC	24.279	Down-regulation
AGC_RSK_RSKp70_RPS6KB1_ST	P23588	EIF4B	P23443	RPS6KB1	S131	P130S	130	Missense	proximal	-1	no	27.474	27.377	EPSD	TCGA;ICGC;COSMIC	24.279	Down-regulation
AGC_RSK_RSKp70_RPS6KB1_ST	P23588	EIF4B	P23443	RPS6KB1	S219	R225Q	225	Missense	distal	6	no	25.633	25.448	EPSD	TCGA;COSMIC	24.279	Down-regulation
AGC_RSK_RSKp70_RPS6KB1_ST	P23588	EIF4B	P23443	RPS6KB1	S219	K223N	223	Missense	distal	4	no	25.633	24.848	EPSD	TCGA	24.279	Down-regulation
AGC_RSK_RSKp70_RPS6KB1_ST	P23588	EIF4B	P23443	RPS6KB1	S230	R227C	227	Missense	distal	-3	no	30.025	20.476	EPSD	TCGA;COSMIC	24.279	Loss
AGC_RSK_RSKp70_RPS6KB1_ST	P23588	EIF4B	P23443	RPS6KB1	S230	R227H	227	Missense	distal	-3	no	30.025	26.537	EPSD	TCGA;COSMIC	24.279	Down-regulation
AGC_RSK_RSKp70_RPS6KB1_ST	P23588	EIF4B	P23443	RPS6KB1	S230	R225Q	225	Missense	distal	-5	no	30.025	18.050	EPSD	TCGA;COSMIC	24.279	Loss
AGC_RSK_RSKp70_RPS6KB1_ST	P23588	EIF4B	P23443	RPS6KB1	S230	K223N	223	Missense	distal	-7	no	30.025	30.045	EPSD	TCGA	24.279	Up-regulation
AGC_RSK_RSKp70_RPS6KB1_ST	P23588	EIF4B	P23443	RPS6KB1	S276	D271N	271	Missense	distal	-5	no	26.212	28.052	EPSD	TCGA;COSMIC	24.279	Up-regulation
AGC_RSK_RSKp70_RPS6KB1_ST	P23588	EIF4B	P23443	RPS6KB1	S276	G275C	275	Missense	proximal	-1	no	26.212	26.229	EPSD	TCGA	24.279	Up-regulation
AGC_RSK_RSKp70_RPS6KB1_ST	P23588	EIF4B	P23443	RPS6KB1	S309	D314V	314	Missense	distal	5	no	24.979	25.147	EPSD	TCGA;COSMIC	24.279	Up-regulation
AGC_RSK_RSKp70_RPS6KB1_ST	P23588	EIF4B	P23443	RPS6KB1	S309	R308Q	308	Missense	proximal	-1	no	24.979	25.007	EPSD	TCGA;COSMIC	24.279	Up-regulation
AGC_RSK_RSKp70_RPS6KB1_ST	P23588	EIF4B	P23443	RPS6KB1	S309	D314H	314	Missense	distal	5	no	24.979	25.942	EPSD	TCGA;COSMIC	24.279	Up-regulation
AGC_RSK_RSKp70_RPS6KB1_ST	P23588	EIF4B	P23443	RPS6KB1	S309	S309P	309	Missense	central	0	yes	24.979	0.000	EPSD	TCGA;COSMIC	24.279	Loss
AGC_RSK_RSKp70_RPS6KB1_ST	P23588	EIF4B	P23443	RPS6KB1	S309	R305Q	305	Missense	distal	-4	no	24.979	22.958	EPSD	TCGA;COSMIC	24.279	Loss
AGC_RSK_RSKp70_RPS6KB1_ST	P23588	EIF4B	P23443	RPS6KB1	S311	D314V	314	Missense	distal	3	no	28.465	27.755	EPSD	TCGA;COSMIC	24.279	Down-regulation
AGC_RSK_RSKp70_RPS6KB1_ST	P23588	EIF4B	P23443	RPS6KB1	S311	R308Q	308	Missense	distal	-3	no	28.465	9.409	EPSD	TCGA;COSMIC	24.279	Loss
AGC_RSK_RSKp70_RPS6KB1_ST	P23588	EIF4B	P23443	RPS6KB1	S311	D314H	314	Missense	distal	3	no	28.465	27.862	EPSD	TCGA;COSMIC	24.279	Down-regulation
AGC_RSK_RSKp70_RPS6KB1_ST	P23588	EIF4B	P23443	RPS6KB1	S311	R318Q	318	Missense	distal	7	no	28.465	29.047	EPSD	TCGA;COSMIC	24.279	Up-regulation
AGC_RSK_RSKp70_RPS6KB1_ST	P23588	EIF4B	P23443	RPS6KB1	S311	S309P	309	Missense	proximal	-2	no	28.465	30.371	EPSD	TCGA;COSMIC	24.279	Up-regulation
AGC_RSK_RSKp70_RPS6KB1_ST	P23588	EIF4B	P23443	RPS6KB1	S311	R305Q	305	Missense	distal	-6	no	28.465	28.499	EPSD	TCGA;COSMIC	24.279	Up-regulation
AGC_RSK_RSKp70_RPS6KB1_ST	P23588	EIF4B	P23443	RPS6KB1	S348	K343R	343	Missense	distal	-5	no	20.445	26.237	EPSD	TCGA;COSMIC	24.279	Gain
AGC_RSK_RSKp70_RPS6KB1_ST	P23588	EIF4B	P23443	RPS6KB1	S352	D346N	346	Missense	distal	-6	no	28.095	28.058	EPSD	TCGA;COSMIC	24.279	Down-regulation
AGC_RSK_RSKp70_RPS6KB1_ST	P23588	EIF4B	P23443	RPS6KB1	S352	A357V	357	Missense	distal	5	no	28.095	27.431	EPSD	TCGA;COSMIC	24.279	Down-regulation
AGC_RSK_RSKp70_RPS6KB1_ST	P23588	EIF4B	P23443	RPS6KB1	S352	R356Q	356	Missense	distal	4	no	28.095	28.180	EPSD	TCGA	24.279	Up-regulation
AGC_RSK_RSKp70_RPS6KB1_ST	P23588	EIF4B	P23443	RPS6KB1	S406	R408Q	408	Missense	proximal	2	no	26.685	24.878	EPSD	TCGA;COSMIC	24.279	Down-regulation
AGC_RSK_RSKp70_RPS6KB1_ST	P23588	EIF4B	P23443	RPS6KB1	S406	R401W	401	Missense	distal	-5	no	26.685	14.722	EPSD	TCGA;COSMIC	24.279	Loss
AGC_RSK_RSKp70_RPS6KB1_ST	P23588	EIF4B	P23443	RPS6KB1	T420	R415L	415	Missense	distal	-5	no	30.157	21.532	EPSD	TCGA;COSMIC	24.279	Loss
AGC_RSK_RSKp70_RPS6KB1_ST	P23588	EIF4B	P23443	RPS6KB1	T420	R417W	417	Missense	distal	-3	no	30.157	15.141	EPSD	TCGA;COSMIC	24.279	Loss
AGC_RSK_RSKp70_RPS6KB1_ST	P23588	EIF4B	P23443	RPS6KB1	S422	R415L	415	Missense	distal	-7	no	44.185	44.290	PhosphoSitePlus	TCGA;COSMIC	24.279	Up-regulation
AGC_RSK_RSKp70_RPS6KB1_ST	P23588	EIF4B	P23443	RPS6KB1	S422	R417W	417	Missense	distal	-5	no	44.185	32.222	PhosphoSitePlus	TCGA;COSMIC	24.279	Down-regulation
AGC_RSK_RSKp70_RPS6KB1_ST	P23588	EIF4B	P23443	RPS6KB1	S430	A437V	437	Missense	distal	7	no	27.290	26.686	EPSD	TCGA;COSMIC	24.279	Down-regulation
AGC_RSK_RSKp70_RPS6KB1_ST	P23588	EIF4B	P23443	RPS6KB1	S433	R438Q	438	Missense	distal	5	no	23.695	24.356	EPSD	TCGA;COSMIC	24.279	Gain
AGC_RSK_RSKp70_RPS6KB1_ST	P23588	EIF4B	P23443	RPS6KB1	S434	A437V	437	Missense	distal	3	no	27.843	28.225	EPSD	TCGA;COSMIC	24.279	Up-regulation
AGC_RSK_RSKp70_RPS6KB1_ST	P23588	EIF4B	P23443	RPS6KB1	S434	R438Q	438	Missense	distal	4	no	27.843	27.929	EPSD	TCGA;COSMIC	24.279	Up-regulation
AGC_RSK_RSKp70_RPS6KB1_ST	P23588	EIF4B	P23443	RPS6KB1	S442	A437V	437	Missense	distal	-5	no	27.234	26.192	EPSD	TCGA;COSMIC	24.279	Down-regulation
AGC_RSK_RSKp70_RPS6KB1_ST	P23588	EIF4B	P23443	RPS6KB1	S442	R438Q	438	Missense	distal	-4	no	27.234	25.213	EPSD	TCGA;COSMIC	24.279	Down-regulation
AGC_RSK_RSKp70_RPS6KB1_ST	P23588	EIF4B	P23443	RPS6KB1	S442	S445Y	445	Missense	distal	3	no	27.234	25.557	EPSD	TCGA	24.279	Down-regulation
AGC_RSK_RSKp70_RPS6KB1_ST	P23588	EIF4B	P23443	RPS6KB1	S445	R438Q	438	Missense	distal	-7	no	25.144	25.214	EPSD	TCGA;COSMIC	24.279	Up-regulation
AGC_RSK_RSKp70_RPS6KB1_ST	P23588	EIF4B	P23443	RPS6KB1	S445	S445Y	445	Missense	central	0	yes	25.144	0.000	EPSD	TCGA	24.279	Loss
AGC_RSK_RSKp70_RPS6KB1_ST	P23588	EIF4B	P23443	RPS6KB1	S459	S462C	462	Missense	distal	3	no	26.806	23.568	EPSD	TCGA;COSMIC	24.279	Loss
AGC_RSK_RSKp70_RPS6KB1_ST	P23588	EIF4B	P23443	RPS6KB1	S459	K463I	463	Missense	distal	4	no	26.806	25.902	EPSD	TCGA;COSMIC	24.279	Down-regulation
AGC_RSK_RSKp70_RPS6KB1_ST	P23588	EIF4B	P23443	RPS6KB1	S459	P465S	465	Missense	distal	6	no	26.806	27.781	EPSD	TCGA;COSMIC	24.279	Up-regulation
AGC_RSK_RSKp70_RPS6KB1_ST	P23588	EIF4B	P23443	RPS6KB1	S459	K463E	463	Missense	distal	4	no	26.806	25.914	EPSD	TCGA;COSMIC	24.279	Down-regulation
AGC_RSK_RSKp70_RPS6KB1_ST	P23588	EIF4B	P23443	RPS6KB1	T461	S462C	462	Missense	proximal	1	no	28.065	29.801	EPSD	TCGA;COSMIC	24.279	Up-regulation
AGC_RSK_RSKp70_RPS6KB1_ST	P23588	EIF4B	P23443	RPS6KB1	T461	K463I	463	Missense	proximal	2	no	28.065	25.978	EPSD	TCGA;COSMIC	24.279	Down-regulation
AGC_RSK_RSKp70_RPS6KB1_ST	P23588	EIF4B	P23443	RPS6KB1	T461	P465S	465	Missense	distal	4	no	28.065	28.998	EPSD	TCGA;COSMIC	24.279	Up-regulation
AGC_RSK_RSKp70_RPS6KB1_ST	P23588	EIF4B	P23443	RPS6KB1	T461	K463E	463	Missense	proximal	2	no	28.065	26.407	EPSD	TCGA;COSMIC	24.279	Down-regulation
AGC_RSK_RSKp70_RPS6KB1_ST	P23588	EIF4B	P23443	RPS6KB1	S495	E501Q	501	Missense	distal	6	no	25.674	25.612	EPSD	TCGA;COSMIC	24.279	Down-regulation
AGC_RSK_RSKp70_RPS6KB1_ST	P23588	EIF4B	P23443	RPS6KB1	S495	Q496E	496	Missense	proximal	1	no	25.674	26.303	EPSD	TCGA;COSMIC	24.279	Up-regulation
AGC_RSK_RSKp70_RPS6KB1_ST	P23588	EIF4B	P23443	RPS6KB1	S498	E501Q	501	Missense	distal	3	no	26.499	23.371	EPSD	TCGA;COSMIC	24.279	Loss
AGC_RSK_RSKp70_RPS6KB1_ST	P23588	EIF4B	P23443	RPS6KB1	S498	Q496E	496	Missense	proximal	-2	no	26.499	26.339	EPSD	TCGA;COSMIC	24.279	Down-regulation
AGC_RSK_RSKp70_RPS6KB1_ST	P23588	EIF4B	P23443	RPS6KB1	S504	E501Q	501	Missense	distal	-3	no	26.035	17.326	EPSD	TCGA;COSMIC	24.279	Loss
AGC_RSK_RSKp70_RPS6KB1_ST	Q9BY77	POLDIP3	P23443	RPS6KB1	S254	L250F	250	Missense	distal	-4	no	29.605	27.731	EPSD	TCGA;ICGC;COSMIC	24.279	Down-regulation
AGC_RSK_RSKp70_RPS6KB1_ST	Q9BY77	POLDIP3	P23443	RPS6KB1	S254	R255Q	255	Missense	proximal	1	no	29.605	29.359	EPSD	TCGA;ICGC;COSMIC	24.279	Down-regulation
AGC_RSK_RSKp70_RPS6KB1_ST	Q9BY77	POLDIP3	P23443	RPS6KB1	S383	R379C	379	Missense	distal	-4	no	35.954	34.561	PhosphoSitePlus;EPSD	TCGA;ICGC;COSMIC	24.279	Down-regulation
AGC_RSK_RSKp70_RPS6KB1_ST	Q9BY77	POLDIP3	P23443	RPS6KB1	S383	R380K	380	Missense	distal	-3	no	35.954	28.334	PhosphoSitePlus;EPSD	TCGA;ICGC;COSMIC	24.279	Down-regulation
AGC_RSK_RSKp70_RPS6KB1_ST	Q9BY77	POLDIP3	P23443	RPS6KB1	S385	R379C	379	Missense	distal	-6	no	35.699	35.739	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	24.279	Up-regulation
AGC_RSK_RSKp70_RPS6KB1_ST	Q9BY77	POLDIP3	P23443	RPS6KB1	S385	R380K	380	Missense	distal	-5	no	35.699	29.907	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	24.279	Down-regulation
Atypical_Alpha_ChaK_TRPM7_ST	Q96QT4	TRPM7	Q96QT4	TRPM7	T89	N96H	96	Missense	distal	7	no	3.909	4.239	EPSD	TCGA;ICGC;COSMIC;GDSC;CCLE	3.661	Up-regulation
Atypical_Alpha_ChaK_TRPM7_ST	Q96QT4	TRPM7	Q96QT4	TRPM7	S1191	R1198C	1198	Missense	distal	7	no	4.075	5.334	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	3.661	Up-regulation
Atypical_Alpha_ChaK_TRPM7_ST	Q96QT4	TRPM7	Q96QT4	TRPM7	S1191	R1198S	1198	Missense	distal	7	no	4.075	4.263	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	3.661	Up-regulation
Atypical_Alpha_ChaK_TRPM7_ST	Q96QT4	TRPM7	Q96QT4	TRPM7	S1191	R1198H	1198	Missense	distal	7	no	4.075	4.821	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	3.661	Up-regulation
Atypical_Alpha_ChaK_TRPM7_ST	Q96QT4	TRPM7	Q96QT4	TRPM7	S1191	H1190Y	1190	Missense	proximal	-1	no	4.075	3.970	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC;GDSC;CCLE	3.661	Down-regulation
Atypical_Alpha_ChaK_TRPM7_ST	Q96QT4	TRPM7	Q96QT4	TRPM7	S1193	R1198C	1198	Missense	distal	5	no	3.735	2.982	PhosphoSitePlus;EPSD	TCGA;ICGC;COSMIC	3.661	Loss
Atypical_Alpha_ChaK_TRPM7_ST	Q96QT4	TRPM7	Q96QT4	TRPM7	S1193	R1198S	1198	Missense	distal	5	no	3.735	4.065	PhosphoSitePlus;EPSD	TCGA;ICGC;COSMIC	3.661	Up-regulation
Atypical_Alpha_ChaK_TRPM7_ST	Q96QT4	TRPM7	Q96QT4	TRPM7	S1193	R1198H	1198	Missense	distal	5	no	3.735	3.489	PhosphoSitePlus;EPSD	TCGA;ICGC;COSMIC	3.661	Loss
Atypical_Alpha_ChaK_TRPM7_ST	Q96QT4	TRPM7	Q96QT4	TRPM7	S1193	H1190Y	1190	Missense	distal	-3	no	3.735	3.715	PhosphoSitePlus;EPSD	TCGA;ICGC;COSMIC;GDSC;CCLE	3.661	Down-regulation
Atypical_Alpha_ChaK_TRPM7_ST	Q96QT4	TRPM7	Q96QT4	TRPM7	S1255	T1248A	1248	Missense	distal	-7	no	3.863	3.845	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	3.661	Down-regulation
Atypical_Alpha_ChaK_TRPM7_ST	Q96QT4	TRPM7	Q96QT4	TRPM7	S1287	P1286L	1286	Missense	proximal	-1	no	3.847	3.682	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	3.661	Down-regulation
Atypical_Alpha_ChaK_TRPM7_ST	Q96QT4	TRPM7	Q96QT4	TRPM7	S1358	P1357S	1357	Missense	proximal	-1	no	5.135	4.460	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	3.661	Down-regulation
Atypical_Alpha_ChaK_TRPM7_ST	Q96QT4	TRPM7	Q96QT4	TRPM7	S1387	H1393Y	1393	Missense	distal	6	no	4.463	4.359	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	3.661	Down-regulation
Atypical_Alpha_ChaK_TRPM7_ST	Q96QT4	TRPM7	Q96QT4	TRPM7	S1387	S1386T	1386	Missense	proximal	-1	no	4.463	4.950	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	3.661	Up-regulation
Atypical_Alpha_ChaK_TRPM7_ST	Q96QT4	TRPM7	Q96QT4	TRPM7	S1387	I1391M	1391	Missense	distal	4	no	4.463	4.417	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	3.661	Down-regulation
Atypical_Alpha_ChaK_TRPM7_ST	Q96QT4	TRPM7	Q96QT4	TRPM7	S1387	S1387P	1387	Missense	central	0	yes	4.463	0.000	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	3.661	Loss
Atypical_Alpha_ChaK_TRPM7_ST	Q96QT4	TRPM7	Q96QT4	TRPM7	S1387	T1389A	1389	Missense	proximal	2	no	4.463	4.440	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	3.661	Down-regulation
Atypical_Alpha_ChaK_TRPM7_ST	Q96QT4	TRPM7	Q96QT4	TRPM7	S1390	H1393Y	1393	Missense	distal	3	no	4.119	4.133	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	3.661	Up-regulation
Atypical_Alpha_ChaK_TRPM7_ST	Q96QT4	TRPM7	Q96QT4	TRPM7	S1390	S1386T	1386	Missense	distal	-4	no	4.119	4.205	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	3.661	Up-regulation
Atypical_Alpha_ChaK_TRPM7_ST	Q96QT4	TRPM7	Q96QT4	TRPM7	S1390	I1391M	1391	Missense	proximal	1	no	4.119	3.995	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	3.661	Down-regulation
Atypical_Alpha_ChaK_TRPM7_ST	Q96QT4	TRPM7	Q96QT4	TRPM7	S1390	S1387P	1387	Missense	distal	-3	no	4.119	4.247	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	3.661	Up-regulation
Atypical_Alpha_ChaK_TRPM7_ST	Q96QT4	TRPM7	Q96QT4	TRPM7	S1390	T1389A	1389	Missense	proximal	-1	no	4.119	4.008	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	3.661	Down-regulation
Atypical_Alpha_ChaK_TRPM7_ST	Q96QT4	TRPM7	Q96QT4	TRPM7	T1435	V1441I	1441	Missense	distal	6	no	4.560	4.499	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	3.661	Down-regulation
Atypical_Alpha_ChaK_TRPM7_ST	Q96QT4	TRPM7	Q96QT4	TRPM7	T1435	A1429T	1429	Missense	distal	-6	no	4.560	4.618	EPSD;PhosphoSitePlus	TCGA;ICGC	3.661	Up-regulation
Atypical_Alpha_ChaK_TRPM7_ST	Q96QT4	TRPM7	Q96QT4	TRPM7	S1446	V1441I	1441	Missense	distal	-5	no	4.149	4.166	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	3.661	Up-regulation
Atypical_Alpha_ChaK_TRPM7_ST	Q96QT4	TRPM7	Q96QT4	TRPM7	S1446	R1451S	1451	Missense	distal	5	no	4.149	4.479	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	3.661	Up-regulation
Atypical_Alpha_ChaK_TRPM7_ST	Q96QT4	TRPM7	Q96QT4	TRPM7	S1456	S1463C	1463	Missense	distal	7	no	3.648	4.719	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	3.661	Gain
Atypical_Alpha_ChaK_TRPM7_ST	Q96QT4	TRPM7	Q96QT4	TRPM7	S1456	R1451S	1451	Missense	distal	-5	no	3.648	3.824	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	3.661	Gain
Atypical_Alpha_ChaK_TRPM7_ST	Q96QT4	TRPM7	Q96QT4	TRPM7	S1468	S1463C	1463	Missense	distal	-5	no	3.848	3.360	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	3.661	Loss
Atypical_Alpha_ChaK_TRPM7_ST	Q96QT4	TRPM7	Q96QT4	TRPM7	S1493	R1486K	1486	Missense	distal	-7	no	4.135	4.110	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	3.661	Down-regulation
Atypical_Alpha_ChaK_TRPM7_ST	Q96QT4	TRPM7	Q96QT4	TRPM7	T1505	D1507H	1507	Missense	proximal	2	no	4.082	4.106	EPSD;PhosphoSitePlus	TCGA;COSMIC	3.661	Up-regulation
Atypical_Alpha_ChaK_TRPM7_ST	Q96QT4	TRPM7	Q96QT4	TRPM7	T1505	E1510G	1510	Missense	distal	5	no	4.082	3.136	EPSD;PhosphoSitePlus	TCGA;COSMIC	3.661	Loss
Atypical_Alpha_ChaK_TRPM7_ST	Q96QT4	TRPM7	Q96QT4	TRPM7	T1508	D1507H	1507	Missense	proximal	-1	no	3.934	3.868	EPSD;PhosphoSitePlus	TCGA;COSMIC	3.661	Down-regulation
Atypical_Alpha_ChaK_TRPM7_ST	Q96QT4	TRPM7	Q96QT4	TRPM7	T1508	E1510G	1510	Missense	proximal	2	no	3.934	4.106	EPSD;PhosphoSitePlus	TCGA;COSMIC	3.661	Up-regulation
Atypical_Alpha_ChaK_TRPM7_ST	Q96QT4	TRPM7	Q96QT4	TRPM7	S1513	D1507H	1507	Missense	distal	-6	no	4.711	4.712	EPSD;PhosphoSitePlus	TCGA;COSMIC	3.661	Up-regulation
Atypical_Alpha_ChaK_TRPM7_ST	Q96QT4	TRPM7	Q96QT4	TRPM7	S1513	E1510G	1510	Missense	distal	-3	no	4.711	4.834	EPSD;PhosphoSitePlus	TCGA;COSMIC	3.661	Up-regulation
Atypical_Alpha_ChaK_TRPM7_ST	Q96QT4	TRPM7	Q96QT4	TRPM7	S1533	R1529I	1529	Missense	distal	-4	no	3.637	3.761	EPSD;PhosphoSitePlus	TCGA	3.661	Gain
Atypical_Alpha_ChaK_TRPM7_ST	Q96QT4	TRPM7	Q96QT4	TRPM7	T1537	P1532S	1532	Missense	distal	-5	no	3.599	3.999	EPSD;PhosphoSitePlus	TCGA	3.661	Gain
Atypical_Alpha_ChaK_TRPM7_ST	Q96QT4	TRPM7	Q96QT4	TRPM7	T1551	Y1555C	1555	Missense	distal	4	no	4.951	4.828	EPSD;PhosphoSitePlus	TCGA;COSMIC	3.661	Down-regulation
Atypical_Alpha_ChaK_TRPM7_ST	Q96QT4	TRPM7	Q96QT4	TRPM7	S1598	I1594T	1594	Missense	distal	-4	no	4.441	4.340	EPSD;PhosphoSitePlus	TCGA;COSMIC	3.661	Down-regulation
Atypical_Alpha_ChaK_TRPM7_ST	Q96QT4	TRPM7	Q96QT4	TRPM7	S1660	Y1662C	1662	Missense	proximal	2	no	3.883	3.989	EPSD;PhosphoSitePlus	TCGA	3.661	Up-regulation
Atypical_Alpha_ChaK_TRPM7_ST	Q96QT4	TRPM7	Q96QT4	TRPM7	T1830	T1830M	1830	Missense	central	0	yes	4.250	0.000	EPSD;PhosphoSitePlus	TCGA;COSMIC	3.661	Loss
Atypical_Alpha_ChaK_TRPM7_ST	P35579	MYH9	Q96QT4	TRPM7	S1803	E1796D	1796	Missense	distal	-7	no	4.692	4.645	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	3.661	Down-regulation
Atypical_Alpha_ChaK_TRPM7_ST	O00418	EEF2K	Q96QT4	TRPM7	S74	E67K	67	Missense	distal	-7	no	3.677	3.598	EPSD	TCGA;ICGC;COSMIC	3.661	Loss
Atypical_Alpha_ChaK_TRPM7_ST	O00418	EEF2K	Q96QT4	TRPM7	S74	H80Y	80	Missense	distal	6	no	3.677	3.572	EPSD	TCGA;ICGC;COSMIC	3.661	Loss
Atypical_Alpha_ChaK_TRPM7_ST	O00418	EEF2K	Q96QT4	TRPM7	S74	R68W	68	Missense	distal	-6	no	3.677	3.909	EPSD	TCGA	3.661	Up-regulation
Atypical_Alpha_ChaK_TRPM7_ST	O00418	EEF2K	Q96QT4	TRPM7	S74	S74C	74	Missense	central	0	yes	3.677	0.000	EPSD	TCGA;ICGC;COSMIC	3.661	Loss
Atypical_Alpha_ChaK_TRPM7_ST	O00418	EEF2K	Q96QT4	TRPM7	S78	H80Y	80	Missense	proximal	2	no	4.007	3.997	PhosphoSitePlus	TCGA;ICGC;COSMIC	3.661	Down-regulation
Atypical_Alpha_ChaK_TRPM7_ST	O00418	EEF2K	Q96QT4	TRPM7	S78	S74C	74	Missense	distal	-4	no	4.007	4.412	PhosphoSitePlus	TCGA;ICGC;COSMIC	3.661	Up-regulation
Atypical_Alpha_ChaK_TRPM7_ST	O00418	EEF2K	Q96QT4	TRPM7	S345	A346S	346	Missense	proximal	1	no	3.923	4.074	EPSD	TCGA;ICGC;COSMIC	3.661	Up-regulation
Atypical_Alpha_ChaK_TRPM7_ST	O00418	EEF2K	Q96QT4	TRPM7	S345	R351K	351	Missense	distal	6	no	3.923	4.026	EPSD	TCGA;ICGC;COSMIC	3.661	Up-regulation
Atypical_Alpha_ChaK_TRPM7_ST	O00418	EEF2K	Q96QT4	TRPM7	S366	S366F	366	Missense	central	0	yes	4.399	0.000	EPSD	TCGA;ICGC;COSMIC	3.661	Loss
Atypical_Alpha_ChaK_TRPM7_ST	O00418	EEF2K	Q96QT4	TRPM7	S366	S366C	366	Missense	central	0	yes	4.399	0.000	EPSD	TCGA;ICGC;COSMIC	3.661	Loss
Atypical_Alpha_ChaK_TRPM7_ST	O00418	EEF2K	Q96QT4	TRPM7	S366	P371S	371	Missense	distal	5	no	4.399	4.711	EPSD	TCGA;ICGC;COSMIC	3.661	Up-regulation
Atypical_Alpha_ChaK_TRPM7_ST	O00418	EEF2K	Q96QT4	TRPM7	S478	V483A	483	Missense	distal	5	no	3.572	3.850	EPSD	TCGA;ICGC;COSMIC	3.661	Gain
Atypical_Alpha_ChaK_TRPM7_ST	O00418	EEF2K	Q96QT4	TRPM7	S478	E472G	472	Missense	distal	-6	no	3.572	3.812	EPSD	TCGA;ICGC;COSMIC	3.661	Gain
Atypical_Alpha_ChaK_TRPM7_ST	O00418	EEF2K	Q96QT4	TRPM7	S622	D621N	621	Missense	proximal	-1	no	3.713	3.472	EPSD	TCGA;ICGC;COSMIC	3.661	Loss
Atypical_Alpha_ChaK_TRPM7_ST	O00418	EEF2K	Q96QT4	TRPM7	S622	A617V	617	Missense	distal	-5	no	3.713	3.703	EPSD	TCGA;ICGC;COSMIC;CCLE	3.661	Down-regulation
Atypical_Alpha_ChaK_TRPM7_ST	O00418	EEF2K	Q96QT4	TRPM7	S622	R618Q	618	Missense	distal	-4	no	3.713	3.672	EPSD	TCGA;ICGC;COSMIC	3.661	Down-regulation
Atypical_Alpha_ChaK_TRPM7_ST	P28289	TMOD1	Q96QT4	TRPM7	T54	G60S	60	Missense	distal	6	no	3.731	4.152	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	3.661	Up-regulation
TK_Axl_MERTK_Y	Q12866	MERTK	Q12866	MERTK	Y749	Y749C	749	Missense	central	0	yes	5.292	0.000	PhosphoSitePlus;EPSD	TCGA;COSMIC	1.889	Loss
TK_Axl_MERTK_Y	Q12866	MERTK	Q12866	MERTK	Y749	G743S	743	Missense	distal	-6	no	5.292	5.217	PhosphoSitePlus;EPSD	TCGA	1.889	Down-regulation
TK_Axl_MERTK_Y	Q12866	MERTK	Q12866	MERTK	Y753	Y749C	749	Missense	distal	-4	no	6.115	6.127	EPSD;PhosphoSitePlus	TCGA;COSMIC	1.889	Up-regulation
TK_Axl_MERTK_Y	Q12866	MERTK	Q12866	MERTK	Y753	R758H	758	Missense	distal	5	no	6.115	6.037	EPSD;PhosphoSitePlus	TCGA;COSMIC	1.889	Down-regulation
TK_Axl_MERTK_Y	Q12866	MERTK	Q12866	MERTK	Y754	Y749C	749	Missense	distal	-5	no	5.341	5.310	EPSD;PhosphoSitePlus	TCGA;COSMIC	1.889	Down-regulation
TK_Axl_MERTK_Y	Q12866	MERTK	Q12866	MERTK	Y754	R758H	758	Missense	distal	4	no	5.341	5.296	EPSD;PhosphoSitePlus	TCGA;COSMIC	1.889	Down-regulation
TK_Axl_MERTK_Y	P42229	STAT5A	Q12866	MERTK	Y171	E178D	178	Missense	distal	7	no	1.910	1.616	EPSD	TCGA;ICGC;COSMIC	1.889	Loss
TK_Axl_MERTK_Y	P42229	STAT5A	Q12866	MERTK	Y694	Q698P	698	Missense	distal	4	no	6.349	6.183	PhosphoSitePlus	TCGA;ICGC	1.889	Down-regulation
TK_Axl_MERTK_Y	P51692	STAT5B	Q12866	MERTK	Y699	A695T	695	Missense	distal	-4	no	5.619	5.575	PhosphoSitePlus	TCGA	1.889	Down-regulation
TK_Axl_MERTK_Y	P51692	STAT5B	Q12866	MERTK	Y699	I704T	704	Missense	distal	5	no	5.619	5.683	PhosphoSitePlus	TCGA;ICGC;COSMIC	1.889	Up-regulation
TK_Axl_MERTK_Y	P51692	STAT5B	Q12866	MERTK	Y699	V700L	700	Missense	proximal	1	no	5.619	5.563	PhosphoSitePlus	TCGA;ICGC;COSMIC	1.889	Down-regulation
TK_Axl_MERTK_Y	P51692	STAT5B	Q12866	MERTK	Y699	A695V	695	Missense	distal	-4	no	5.619	5.563	PhosphoSitePlus	TCGA;ICGC;COSMIC	1.889	Down-regulation
TK_Axl_MERTK_Y	P40763	STAT3	Q12866	MERTK	Y686	Y686D	686	Missense	central	0	yes	2.832	0.000	EPSD	TCGA;ICGC	1.889	Loss
TK_Axl_MERTK_Y	P40763	STAT3	Q12866	MERTK	Y686	A682T	682	Missense	distal	-4	no	2.832	2.788	EPSD	TCGA;ICGC	1.889	Down-regulation
TK_Axl_MERTK_Y	P40763	STAT3	Q12866	MERTK	Y686	K679N	679	Missense	distal	-7	no	2.832	2.791	EPSD	TCGA;ICGC	1.889	Down-regulation
STE_STE20_PAKB_PAK6_ST	Q9BY11	PACSIN1	Q9NQU5	PAK6	T16	W20C	20	Missense	distal	4	no	1.516	1.520	EPSD	TCGA;ICGC;COSMIC	1.514	Up-regulation
STE_STE20_PAKB_PAK6_ST	Q9BY11	PACSIN1	Q9NQU5	PAK6	T16	P12Q	12	Missense	distal	-4	no	1.516	1.508	EPSD	TCGA;ICGC;COSMIC	1.514	Loss
STE_STE20_PAKB_PAK6_ST	Q9BY11	PACSIN1	Q9NQU5	PAK6	T16	V22M	22	Missense	distal	6	no	1.516	1.512	EPSD	TCGA;ICGC;COSMIC	1.514	Loss
STE_STE20_PAKB_PAK6_ST	Q9BY11	PACSIN1	Q9NQU5	PAK6	T28	V22M	22	Missense	distal	-6	no	2.423	2.414	EPSD	TCGA;ICGC;COSMIC	1.514	Down-regulation
STE_STE20_PAKB_PAK6_ST	Q9BY11	PACSIN1	Q9NQU5	PAK6	S339	D343N	343	Missense	distal	4	no	1.782	1.772	EPSD	TCGA;ICGC;COSMIC	1.514	Down-regulation
STE_STE20_PAKB_PAK6_ST	Q9BY11	PACSIN1	Q9NQU5	PAK6	S339	G345S	345	Missense	distal	6	no	1.782	1.743	EPSD	TCGA;ICGC;COSMIC;GDSC;CCLE	1.514	Down-regulation
STE_STE20_PAKB_PAK6_ST	Q9BY11	PACSIN1	Q9NQU5	PAK6	S346	D351E	351	Missense	distal	5	no	4.590	4.239	PhosphoSitePlus	TCGA;ICGC;COSMIC	1.514	Down-regulation
STE_STE20_PAKB_PAK6_ST	Q9BY11	PACSIN1	Q9NQU5	PAK6	S346	D343N	343	Missense	distal	-3	no	4.590	4.809	PhosphoSitePlus	TCGA;ICGC;COSMIC	1.514	Up-regulation
STE_STE20_PAKB_PAK6_ST	Q9BY11	PACSIN1	Q9NQU5	PAK6	S346	G345S	345	Missense	proximal	-1	no	4.590	4.577	PhosphoSitePlus	TCGA;ICGC;COSMIC;GDSC;CCLE	1.514	Down-regulation
STE_STE20_PAKB_PAK6_ST	Q9BY11	PACSIN1	Q9NQU5	PAK6	S346	D351N	351	Missense	distal	5	no	4.590	4.302	PhosphoSitePlus	TCGA;ICGC;COSMIC	1.514	Down-regulation
STE_STE20_PAKB_PAK6_ST	P10275	AR	Q9NQU5	PAK6	S310	E308K	308	Missense	proximal	-2	no	1.567	1.489	EPSD	TCGA;COSMIC	1.514	Loss
STE_STE20_PAKB_PAK6_ST	P10275	AR	Q9NQU5	PAK6	S310	Y316H	316	Missense	distal	6	no	1.567	1.551	EPSD	TCGA;ICGC	1.514	Down-regulation
STE_STE20_PAKB_PAK6_ST	P10275	AR	Q9NQU5	PAK6	S579	F583I	583	Missense	distal	4	no	4.575	4.580	PhosphoSitePlus	TCGA;ICGC;COSMIC	1.514	Up-regulation
STE_STE20_PAKB_PAK6_ST	P10275	AR	Q9NQU5	PAK6	S579	G578R	578	Missense	proximal	-1	no	4.575	4.580	PhosphoSitePlus	TCGA;ICGC;COSMIC	1.514	Up-regulation
STE_STE20_PAKB_PAK6_ST	P10275	AR	Q9NQU5	PAK6	T656	T661S	661	Missense	distal	5	no	1.491	1.796	EPSD	TCGA;ICGC	1.514	Gain
STE_STE20_PAKB_PAK6_ST	Q13363	CTBP1	Q9NQU5	PAK6	T80	E87Q	87	Missense	distal	7	no	1.494	1.532	EPSD	TCGA;COSMIC	1.514	Gain
STE_STE20_PAKB_PAK6_ST	Q13363	CTBP1	Q9NQU5	PAK6	S298	S298G	298	Missense	central	0	yes	2.054	0.000	EPSD	TCGA	1.514	Loss
STE_STE20_PAKB_PAK6_ST	Q13363	CTBP1	Q9NQU5	PAK6	S298	K305N	305	Missense	distal	7	no	2.054	2.086	EPSD	TCGA;COSMIC	1.514	Up-regulation
STE_STE20_PAKB_PAK6_ST	P53667	LIMK1	Q9NQU5	PAK6	T270	P276L	276	Missense	distal	6	no	2.045	2.060	EPSD	TCGA;COSMIC;CCLE	1.514	Up-regulation
STE_STE20_PAKB_PAK6_ST	P53667	LIMK1	Q9NQU5	PAK6	S296	R289Q	289	Missense	distal	-7	no	1.769	1.730	EPSD	TCGA;COSMIC	1.514	Down-regulation
STE_STE20_PAKB_PAK6_ST	P53667	LIMK1	Q9NQU5	PAK6	S296	P303T	303	Missense	distal	7	no	1.769	1.724	EPSD	TCGA;COSMIC	1.514	Down-regulation
STE_STE20_PAKB_PAK6_ST	P53667	LIMK1	Q9NQU5	PAK6	S296	R289W	289	Missense	distal	-7	no	1.769	1.729	EPSD	TCGA;COSMIC	1.514	Down-regulation
STE_STE20_PAKB_PAK6_ST	P53667	LIMK1	Q9NQU5	PAK6	S427	S430T	430	Missense	distal	3	no	1.865	1.859	EPSD	TCGA;COSMIC	1.514	Down-regulation
STE_STE20_PAKB_PAK6_ST	P53667	LIMK1	Q9NQU5	PAK6	T508	D502G	502	Missense	distal	-6	no	4.476	4.469	PhosphoSitePlus	TCGA;COSMIC	1.514	Down-regulation
STE_STE20_PAKB_PAK6_ST	P53667	LIMK1	Q9NQU5	PAK6	T508	P513L	513	Missense	distal	5	no	4.476	4.520	PhosphoSitePlus	TCGA;COSMIC	1.514	Up-regulation
STE_STE20_PAKA_PAK1_ST	P36871	PGM1	Q13153	PAK1	S408	R405C	405	Missense	distal	-3	no	22.089	2.133	EPSD	TCGA;ICGC;COSMIC	19.028	Loss
STE_STE20_PAKA_PAK1_ST	P51114	FXR1	Q13153	PAK1	S11	V8G	8	Missense	distal	-3	no	14.435	20.444	EPSD	TCGA	19.028	Gain
STE_STE20_PAKA_PAK1_ST	P51114	FXR1	Q13153	PAK1	S60	I59V	59	Missense	proximal	-1	no	22.108	20.564	EPSD	TCGA	19.028	Down-regulation
STE_STE20_PAKA_PAK1_ST	P51114	FXR1	Q13153	PAK1	S60	D54Y	54	Missense	distal	-6	no	22.108	21.009	EPSD	TCGA;ICGC;COSMIC	19.028	Down-regulation
STE_STE20_PAKA_PAK1_ST	P51114	FXR1	Q13153	PAK1	S60	V65I	65	Missense	distal	5	no	22.108	22.099	EPSD	TCGA;ICGC	19.028	Down-regulation
STE_STE20_PAKA_PAK1_ST	P51114	FXR1	Q13153	PAK1	T396	R390C	390	Missense	distal	-6	no	21.243	17.538	EPSD	TCGA;ICGC;COSMIC	19.028	Loss
STE_STE20_PAKA_PAK1_ST	P51114	FXR1	Q13153	PAK1	T396	G392E	392	Missense	distal	-4	no	21.243	21.844	EPSD	TCGA;ICGC;COSMIC	19.028	Up-regulation
STE_STE20_PAKA_PAK1_ST	P51114	FXR1	Q13153	PAK1	S413	E410K	410	Missense	distal	-3	no	6.724	20.516	EPSD	TCGA;ICGC;COSMIC	19.028	Gain
STE_STE20_PAKA_PAK1_ST	P51114	FXR1	Q13153	PAK1	S420	D417H	417	Missense	distal	-3	no	21.034	21.919	PhosphoSitePlus	TCGA;ICGC;COSMIC	19.028	Up-regulation
STE_STE20_PAKA_PAK1_ST	P51114	FXR1	Q13153	PAK1	S420	S413C	413	Missense	distal	-7	no	21.034	19.337	PhosphoSitePlus	TCGA;ICGC;COSMIC	19.028	Down-regulation
STE_STE20_PAKA_PAK1_ST	P51114	FXR1	Q13153	PAK1	S420	D421N	421	Missense	proximal	1	no	21.034	21.025	PhosphoSitePlus	TCGA;ICGC;COSMIC	19.028	Down-regulation
STE_STE20_PAKA_PAK1_ST	P51114	FXR1	Q13153	PAK1	S420	E414Q	414	Missense	distal	-6	no	21.034	20.674	PhosphoSitePlus	TCGA;ICGC;COSMIC	19.028	Down-regulation
STE_STE20_PAKA_PAK1_ST	P51114	FXR1	Q13153	PAK1	S420	R415H	415	Missense	distal	-5	no	21.034	21.480	PhosphoSitePlus	TCGA;ICGC;COSMIC	19.028	Up-regulation
STE_STE20_PAKA_PAK1_ST	P51114	FXR1	Q13153	PAK1	S438	R433Q	433	Missense	distal	-5	no	20.036	20.134	EPSD	TCGA;ICGC;COSMIC;GDSC;CCLE	19.028	Up-regulation
STE_STE20_PAKA_PAK1_ST	P51114	FXR1	Q13153	PAK1	S438	R440I	440	Missense	proximal	2	no	20.036	20.571	EPSD	TCGA;ICGC;COSMIC	19.028	Up-regulation
STE_STE20_PAKA_PAK1_ST	P51114	FXR1	Q13153	PAK1	S438	R436H	436	Missense	proximal	-2	no	20.036	14.622	EPSD	TCGA;ICGC;COSMIC	19.028	Loss
STE_STE20_PAKA_PAK1_ST	P51114	FXR1	Q13153	PAK1	S438	D437G	437	Missense	proximal	-1	no	20.036	17.677	EPSD	TCGA;ICGC	19.028	Loss
STE_STE20_PAKA_PAK1_ST	P51114	FXR1	Q13153	PAK1	S448	S450L	450	Missense	proximal	2	no	23.559	24.373	EPSD	TCGA;ICGC;COSMIC	19.028	Up-regulation
STE_STE20_PAKA_PAK1_ST	P51114	FXR1	Q13153	PAK1	S448	R455H	455	Missense	distal	7	no	23.559	23.607	EPSD	TCGA;ICGC;COSMIC	19.028	Up-regulation
STE_STE20_PAKA_PAK1_ST	P51114	FXR1	Q13153	PAK1	S450	S450L	450	Missense	central	0	yes	20.541	0.000	EPSD	TCGA;ICGC;COSMIC	19.028	Loss
STE_STE20_PAKA_PAK1_ST	P51114	FXR1	Q13153	PAK1	S450	R455H	455	Missense	distal	5	no	20.541	20.553	EPSD	TCGA;ICGC;COSMIC	19.028	Up-regulation
STE_STE20_PAKA_PAK1_ST	P51114	FXR1	Q13153	PAK1	S464	S467Y	467	Missense	distal	3	no	15.430	19.209	EPSD	TCGA;ICGC;COSMIC	19.028	Gain
STE_STE20_PAKA_PAK1_ST	P51114	FXR1	Q13153	PAK1	S474	S467Y	467	Missense	distal	-7	no	21.783	20.273	EPSD	TCGA;ICGC;COSMIC	19.028	Down-regulation
STE_STE20_PAKA_PAK1_ST	P51114	FXR1	Q13153	PAK1	S474	S474N	474	Missense	central	0	yes	21.783	0.000	EPSD	TCGA;ICGC;COSMIC	19.028	Loss
STE_STE20_PAKA_PAK1_ST	P51114	FXR1	Q13153	PAK1	S506	D512N	512	Missense	distal	6	no	24.627	24.772	EPSD	TCGA;ICGC;COSMIC	19.028	Up-regulation
STE_STE20_PAKA_PAK1_ST	P51114	FXR1	Q13153	PAK1	S506	T511I	511	Missense	distal	5	no	24.627	24.632	EPSD	TCGA;ICGC;COSMIC	19.028	Up-regulation
STE_STE20_PAKA_PAK1_ST	P51114	FXR1	Q13153	PAK1	S506	R503S	503	Missense	distal	-3	no	24.627	15.956	EPSD	TCGA;ICGC;COSMIC	19.028	Loss
STE_STE20_PAKA_PAK1_ST	P51114	FXR1	Q13153	PAK1	S506	R503C	503	Missense	distal	-3	no	24.627	4.672	EPSD	TCGA;ICGC;GDSC;CCLE	19.028	Loss
STE_STE20_PAKA_PAK1_ST	P51114	FXR1	Q13153	PAK1	S506	R509Q	509	Missense	distal	3	no	24.627	25.127	EPSD	TCGA;ICGC;COSMIC;CCLE	19.028	Up-regulation
STE_STE20_PAKA_PAK1_ST	P51114	FXR1	Q13153	PAK1	S506	R505W	505	Missense	proximal	-1	no	24.627	21.007	EPSD	TCGA;ICGC;COSMIC	19.028	Down-regulation
STE_STE20_PAKA_PAK1_ST	P51114	FXR1	Q13153	PAK1	S506	R502H	502	Missense	distal	-4	no	24.627	24.193	EPSD	TCGA;ICGC;COSMIC	19.028	Down-regulation
STE_STE20_PAKA_PAK1_ST	P51114	FXR1	Q13153	PAK1	S506	R505Q	505	Missense	proximal	-1	no	24.627	22.908	EPSD	TCGA;ICGC;COSMIC;GDSC;CCLE	19.028	Down-regulation
STE_STE20_PAKA_PAK1_ST	P51114	FXR1	Q13153	PAK1	S506	R503H	503	Missense	distal	-3	no	24.627	18.556	EPSD	TCGA;ICGC	19.028	Loss
STE_STE20_PAKA_PAK1_ST	P51114	FXR1	Q13153	PAK1	T511	D512N	512	Missense	proximal	1	no	30.028	30.019	EPSD	TCGA;ICGC;COSMIC	19.028	Down-regulation
STE_STE20_PAKA_PAK1_ST	P51114	FXR1	Q13153	PAK1	T511	T511I	511	Missense	central	0	yes	30.028	0.000	EPSD	TCGA;ICGC;COSMIC	19.028	Loss
STE_STE20_PAKA_PAK1_ST	P51114	FXR1	Q13153	PAK1	T511	D514H	514	Missense	distal	3	no	30.028	28.998	EPSD	TCGA;ICGC;COSMIC	19.028	Down-regulation
STE_STE20_PAKA_PAK1_ST	P51114	FXR1	Q13153	PAK1	T511	R509Q	509	Missense	proximal	-2	no	30.028	20.821	EPSD	TCGA;ICGC;COSMIC;CCLE	19.028	Down-regulation
STE_STE20_PAKA_PAK1_ST	P51114	FXR1	Q13153	PAK1	T511	R505W	505	Missense	distal	-6	no	30.028	27.404	EPSD	TCGA;ICGC;COSMIC	19.028	Down-regulation
STE_STE20_PAKA_PAK1_ST	P51114	FXR1	Q13153	PAK1	T511	R505Q	505	Missense	distal	-6	no	30.028	28.766	EPSD	TCGA;ICGC;COSMIC;GDSC;CCLE	19.028	Down-regulation
STE_STE20_PAKA_PAK1_ST	P51114	FXR1	Q13153	PAK1	S542	D539Y	539	Missense	distal	-3	no	18.388	19.577	EPSD	TCGA;COSMIC	19.028	Gain
STE_STE20_PAKA_PAK1_ST	P51114	FXR1	Q13153	PAK1	S585	G582D	582	Missense	distal	-3	no	18.348	19.268	EPSD	TCGA;COSMIC	19.028	Gain
STE_STE20_PAKA_PAK1_ST	Q13153	PAK1	Q13153	PAK1	S21	G27D	27	Missense	distal	6	no	26.453	26.130	EPSD	TCGA;ICGC;COSMIC	19.028	Down-regulation
STE_STE20_PAKA_PAK1_ST	Q13153	PAK1	Q13153	PAK1	S21	M23T	23	Missense	proximal	2	no	26.453	24.689	EPSD	TCGA;ICGC;COSMIC	19.028	Down-regulation
STE_STE20_PAKA_PAK1_ST	Q13153	PAK1	Q13153	PAK1	S21	A26V	26	Missense	distal	5	no	26.453	26.454	EPSD	TCGA;ICGC;COSMIC	19.028	Up-regulation
STE_STE20_PAKA_PAK1_ST	Q13153	PAK1	Q13153	PAK1	S21	S28N	28	Missense	distal	7	no	26.453	26.438	EPSD	TCGA;ICGC;COSMIC	19.028	Down-regulation
STE_STE20_PAKA_PAK1_ST	Q13153	PAK1	Q13153	PAK1	S57	R56Q	56	Missense	proximal	-1	no	24.285	22.566	EPSD	TCGA;ICGC;COSMIC	19.028	Down-regulation
STE_STE20_PAKA_PAK1_ST	Q13153	PAK1	Q13153	PAK1	S57	R53Q	53	Missense	distal	-4	no	24.285	23.816	EPSD	TCGA;ICGC;COSMIC;GDSC;CCLE	19.028	Down-regulation
STE_STE20_PAKA_PAK1_ST	Q13153	PAK1	Q13153	PAK1	S165	T167S	167	Missense	proximal	2	no	20.746	21.484	EPSD	TCGA;ICGC;COSMIC	19.028	Up-regulation
STE_STE20_PAKA_PAK1_ST	Q13153	PAK1	Q13153	PAK1	S165	E166V	166	Missense	proximal	1	no	20.746	20.494	EPSD	TCGA;ICGC;COSMIC	19.028	Down-regulation
STE_STE20_PAKA_PAK1_ST	Q13153	PAK1	Q13153	PAK1	S165	E166D	166	Missense	proximal	1	no	20.746	20.671	EPSD	TCGA;ICGC;COSMIC	19.028	Down-regulation
STE_STE20_PAKA_PAK1_ST	Q13153	PAK1	Q13153	PAK1	S259	D265Y	265	Missense	distal	6	no	21.435	22.039	EPSD	TCGA;ICGC;COSMIC	19.028	Up-regulation
STE_STE20_PAKA_PAK1_ST	Q13153	PAK1	Q13153	PAK1	S259	G264C	264	Missense	distal	5	no	21.435	21.427	EPSD	TCGA;ICGC;COSMIC	19.028	Down-regulation
STE_STE20_PAKA_PAK1_ST	Q13153	PAK1	Q13153	PAK1	T271	D265Y	265	Missense	distal	-6	no	19.302	18.203	EPSD	TCGA;ICGC;COSMIC	19.028	Loss
STE_STE20_PAKA_PAK1_ST	Q13153	PAK1	Q13153	PAK1	T271	G264C	264	Missense	distal	-7	no	19.302	18.542	EPSD	TCGA;ICGC;COSMIC	19.028	Loss
STE_STE20_PAKA_PAK1_ST	Q13153	PAK1	Q13153	PAK1	T423	E417Q	417	Missense	distal	-6	no	30.000	29.640	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	19.028	Down-regulation
STE_STE20_PAKA_PAK1_ST	Q13153	PAK1	Q13153	PAK1	T423	R421L	421	Missense	proximal	-2	no	30.000	21.436	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	19.028	Down-regulation
STE_STE20_PAKA_PAK1_ST	Q13153	PAK1	Q13153	PAK1	T437	E434K	434	Missense	distal	-3	no	5.473	19.264	EPSD	TCGA;ICGC;COSMIC	19.028	Gain
STE_STE20_PAKA_PAK1_ST	O15143	ARPC1B	Q13153	PAK1	T21	Q22H	22	Missense	proximal	1	no	21.594	21.668	PhosphoSitePlus	TCGA;ICGC;COSMIC	19.028	Up-regulation
STE_STE20_PAKA_PAK1_ST	O15143	ARPC1B	Q13153	PAK1	T21	R20C	20	Missense	proximal	-1	no	21.594	17.374	PhosphoSitePlus	TCGA;ICGC	19.028	Loss
STE_STE20_PAKA_PAK1_ST	O15143	ARPC1B	Q13153	PAK1	S170	K165N	165	Missense	distal	-5	no	21.863	22.382	EPSD	TCGA;ICGC;COSMIC	19.028	Up-regulation
STE_STE20_PAKA_PAK1_ST	O15143	ARPC1B	Q13153	PAK1	S187	W185L	185	Missense	proximal	-2	no	15.404	19.779	EPSD	TCGA;ICGC;COSMIC	19.028	Gain
STE_STE20_PAKA_PAK1_ST	O15143	ARPC1B	Q13153	PAK1	S310	S311F	311	Missense	proximal	1	no	21.527	21.787	EPSD	TCGA;ICGC;COSMIC	19.028	Up-regulation
STE_STE20_PAKA_PAK1_ST	O15143	ARPC1B	Q13153	PAK1	S311	S311F	311	Missense	central	0	yes	22.081	0.000	EPSD	TCGA;ICGC;COSMIC	19.028	Loss
STE_STE20_PAKA_PAK1_ST	P19086	GNAZ	Q13153	PAK1	S16	R18I	18	Missense	proximal	2	no	28.087	28.623	PhosphoSitePlus	TCGA;ICGC;COSMIC	19.028	Up-regulation
STE_STE20_PAKA_PAK1_ST	P19086	GNAZ	Q13153	PAK1	S16	E9K	9	Missense	distal	-7	no	28.087	27.360	PhosphoSitePlus	TCGA;ICGC;COSMIC;GDSC;CCLE	19.028	Down-regulation
STE_STE20_PAKA_PAK1_ST	P19086	GNAZ	Q13153	PAK1	S16	R15W	15	Missense	proximal	-1	no	28.087	24.467	PhosphoSitePlus	TCGA;ICGC;COSMIC	19.028	Down-regulation
STE_STE20_PAKA_PAK1_ST	P19086	GNAZ	Q13153	PAK1	S16	R17G	17	Missense	proximal	1	no	28.087	27.606	PhosphoSitePlus	TCGA;ICGC;COSMIC	19.028	Down-regulation
STE_STE20_PAKA_PAK1_ST	P19086	GNAZ	Q13153	PAK1	S16	K10N	10	Missense	distal	-6	no	28.087	28.508	PhosphoSitePlus	TCGA;ICGC;COSMIC	19.028	Up-regulation
STE_STE20_PAKA_PAK1_ST	P19086	GNAZ	Q13153	PAK1	S16	R14Q	14	Missense	proximal	-2	no	28.087	18.881	PhosphoSitePlus	TCGA;ICGC;COSMIC	19.028	Loss
STE_STE20_PAKA_PAK1_ST	P19086	GNAZ	Q13153	PAK1	S27	R24P	24	Missense	distal	-3	no	20.135	14.452	EPSD	TCGA;ICGC;COSMIC	19.028	Loss
STE_STE20_PAKA_PAK1_ST	P19086	GNAZ	Q13153	PAK1	S27	R31H	31	Missense	distal	4	no	20.135	20.999	EPSD	TCGA;ICGC;COSMIC	19.028	Up-regulation
STE_STE20_PAKA_PAK1_ST	P19086	GNAZ	Q13153	PAK1	S27	R29W	29	Missense	proximal	2	no	20.135	21.973	EPSD	TCGA;ICGC;COSMIC	19.028	Up-regulation
STE_STE20_PAKA_PAK1_ST	P19086	GNAZ	Q13153	PAK1	T182	R177H	177	Missense	distal	-5	no	22.092	22.539	EPSD	TCGA;ICGC;COSMIC	19.028	Up-regulation
STE_STE20_PAKA_PAK1_ST	P19086	GNAZ	Q13153	PAK1	T182	R177P	177	Missense	distal	-5	no	22.092	22.984	EPSD	TCGA;ICGC;COSMIC	19.028	Up-regulation
STE_STE20_PAKA_PAK1_ST	P19086	GNAZ	Q13153	PAK1	T182	S178F	178	Missense	distal	-4	no	22.092	22.374	EPSD	TCGA;ICGC;COSMIC	19.028	Up-regulation
STE_STE20_PAKA_PAK1_ST	P19086	GNAZ	Q13153	PAK1	T182	I175T	175	Missense	distal	-7	no	22.092	22.888	EPSD	TCGA;ICGC;COSMIC	19.028	Up-regulation
STE_STE20_PAKA_PAK1_ST	P04049	RAF1	Q13153	PAK1	S12	F17S	17	Missense	distal	5	no	23.349	23.342	EPSD	TCGA;ICGC;COSMIC	19.028	Down-regulation
STE_STE20_PAKA_PAK1_ST	P04049	RAF1	Q13153	PAK1	S12	D19Y	19	Missense	distal	7	no	23.349	23.603	EPSD	TCGA;ICGC;COSMIC	19.028	Up-regulation
STE_STE20_PAKA_PAK1_ST	P04049	RAF1	Q13153	PAK1	S43	Q39E	39	Missense	distal	-4	no	27.696	27.878	EPSD	TCGA;COSMIC	19.028	Up-regulation
STE_STE20_PAKA_PAK1_ST	P04049	RAF1	Q13153	PAK1	S43	R41W	41	Missense	proximal	-2	no	27.696	14.757	EPSD	TCGA;COSMIC	19.028	Loss
STE_STE20_PAKA_PAK1_ST	P04049	RAF1	Q13153	PAK1	S199	N198K	198	Missense	proximal	-1	no	19.449	22.802	EPSD	TCGA;ICGC	19.028	Up-regulation
STE_STE20_PAKA_PAK1_ST	P04049	RAF1	Q13153	PAK1	S220	R215C	215	Missense	distal	-5	no	19.644	20.399	EPSD	TCGA;ICGC;COSMIC	19.028	Up-regulation
STE_STE20_PAKA_PAK1_ST	P04049	RAF1	Q13153	PAK1	S220	R223M	223	Missense	distal	3	no	19.644	21.375	EPSD	TCGA;ICGC;COSMIC	19.028	Up-regulation
STE_STE20_PAKA_PAK1_ST	P04049	RAF1	Q13153	PAK1	S220	P225H	225	Missense	distal	5	no	19.644	19.628	EPSD	TCGA;ICGC	19.028	Down-regulation
STE_STE20_PAKA_PAK1_ST	P04049	RAF1	Q13153	PAK1	T258	S257L	257	Missense	proximal	-1	no	18.882	19.830	EPSD	TCGA;COSMIC;GDSC;CCLE	19.028	Gain
STE_STE20_PAKA_PAK1_ST	P04049	RAF1	Q13153	PAK1	T258	S259F	259	Missense	proximal	1	no	18.882	19.142	EPSD	TCGA;COSMIC;GDSC;CCLE	19.028	Gain
STE_STE20_PAKA_PAK1_ST	P04049	RAF1	Q13153	PAK1	T258	H264Y	264	Missense	distal	6	no	18.882	19.346	EPSD	TCGA;COSMIC	19.028	Gain
STE_STE20_PAKA_PAK1_ST	P04049	RAF1	Q13153	PAK1	S259	S257L	257	Missense	proximal	-2	no	24.769	24.357	EPSD	TCGA;COSMIC;GDSC;CCLE	19.028	Down-regulation
STE_STE20_PAKA_PAK1_ST	P04049	RAF1	Q13153	PAK1	S259	P261R	261	Missense	proximal	2	no	24.769	23.737	EPSD	TCGA;COSMIC;CCLE	19.028	Down-regulation
STE_STE20_PAKA_PAK1_ST	P04049	RAF1	Q13153	PAK1	S259	S257W	257	Missense	proximal	-2	no	24.769	19.983	EPSD	TCGA;COSMIC	19.028	Down-regulation
STE_STE20_PAKA_PAK1_ST	P04049	RAF1	Q13153	PAK1	S259	S259F	259	Missense	central	0	yes	24.769	0.000	EPSD	TCGA;COSMIC;GDSC;CCLE	19.028	Loss
STE_STE20_PAKA_PAK1_ST	P04049	RAF1	Q13153	PAK1	S259	H264Y	264	Missense	distal	5	no	24.769	24.788	EPSD	TCGA;COSMIC	19.028	Up-regulation
STE_STE20_PAKA_PAK1_ST	P04049	RAF1	Q13153	PAK1	T310	T303A	303	Missense	distal	-7	no	19.080	18.937	EPSD	TCGA;COSMIC	19.028	Loss
STE_STE20_PAKA_PAK1_ST	P04049	RAF1	Q13153	PAK1	S338	R333H	333	Missense	distal	-5	no	27.636	28.083	EPSD;PhosphoSitePlus	TCGA;COSMIC	19.028	Up-regulation
STE_STE20_PAKA_PAK1_ST	P04049	RAF1	Q13153	PAK1	S338	S339I	339	Missense	proximal	1	no	27.636	27.883	EPSD;PhosphoSitePlus	TCGA	19.028	Up-regulation
STE_STE20_PAKA_PAK1_ST	P04049	RAF1	Q13153	PAK1	S339	R333H	333	Missense	distal	-6	no	26.983	26.124	PhosphoSitePlus;EPSD	TCGA;COSMIC	19.028	Down-regulation
STE_STE20_PAKA_PAK1_ST	P04049	RAF1	Q13153	PAK1	S339	S339I	339	Missense	central	0	yes	26.983	0.000	PhosphoSitePlus;EPSD	TCGA	19.028	Loss
STE_STE20_PAKA_PAK1_ST	P04049	RAF1	Q13153	PAK1	S357	M350T	350	Missense	distal	-7	no	18.996	20.597	EPSD	TCGA;COSMIC	19.028	Gain
STE_STE20_PAKA_PAK1_ST	Q13418	ILK	Q13153	PAK1	T167	N160D	160	Missense	distal	-7	no	20.162	20.567	EPSD	TCGA;COSMIC	19.028	Up-regulation
STE_STE20_PAKA_PAK1_ST	Q13418	ILK	Q13153	PAK1	T167	T173A	173	Missense	distal	6	no	20.162	20.453	EPSD	TCGA;ICGC;COSMIC	19.028	Up-regulation
STE_STE20_PAKA_PAK1_ST	Q13418	ILK	Q13153	PAK1	T167	I162T	162	Missense	distal	-5	no	20.162	20.167	EPSD	TCGA	19.028	Up-regulation
STE_STE20_PAKA_PAK1_ST	Q13418	ILK	Q13153	PAK1	S232	K231N	231	Missense	proximal	-1	no	25.033	21.680	EPSD	TCGA;ICGC;COSMIC	19.028	Down-regulation
STE_STE20_PAKA_PAK1_ST	Q13418	ILK	Q13153	PAK1	S232	R225Q	225	Missense	distal	-7	no	25.033	24.510	EPSD	TCGA;COSMIC	19.028	Down-regulation
STE_STE20_PAKA_PAK1_ST	Q13418	ILK	Q13153	PAK1	S246	R241Q	241	Missense	distal	-5	no	22.329	22.427	PhosphoSitePlus;EPSD	TCGA;COSMIC	19.028	Up-regulation
STE_STE20_PAKA_PAK1_ST	Q13418	ILK	Q13153	PAK1	S246	S246L	246	Missense	central	0	yes	22.329	0.000	PhosphoSitePlus;EPSD	TCGA;COSMIC	19.028	Loss
STE_STE20_PAKA_PAK1_ST	Q13418	ILK	Q13153	PAK1	S336	R334Q	334	Missense	proximal	-2	no	21.384	12.177	EPSD	TCGA;COSMIC	19.028	Loss
STE_STE20_PAKA_PAK1_ST	Q92934	BAD	Q13153	PAK1	S74	S71I	71	Missense	distal	-3	no	20.464	13.668	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	19.028	Loss
STE_STE20_PAKA_PAK1_ST	Q92934	BAD	Q13153	PAK1	S75	S71I	71	Missense	distal	-4	no	25.891	26.129	PhosphoSitePlus;EPSD	TCGA;ICGC;COSMIC	19.028	Up-regulation
STE_STE20_PAKA_PAK1_ST	Q92934	BAD	Q13153	PAK1	S97	A100T	100	Missense	distal	3	no	20.391	19.145	EPSD	TCGA;ICGC;COSMIC	19.028	Down-regulation
STE_STE20_PAKA_PAK1_ST	Q92934	BAD	Q13153	PAK1	S99	A100T	100	Missense	proximal	1	no	26.257	26.752	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	19.028	Up-regulation
STE_STE20_PAKA_PAK1_ST	Q92934	BAD	Q13153	PAK1	S118	M117I	117	Missense	proximal	-1	no	30.333	31.799	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	19.028	Up-regulation
STE_STE20_PAKA_PAK1_ST	Q92934	BAD	Q13153	PAK1	S134	R131H	131	Missense	distal	-3	no	25.807	19.736	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	19.028	Down-regulation
STE_STE20_PAKA_PAK1_ST	Q92934	BAD	Q13153	PAK1	S134	G136D	136	Missense	proximal	2	no	25.807	24.996	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	19.028	Down-regulation
STE_STE20_PAKA_PAK1_ST	Q92934	BAD	Q13153	PAK1	S134	S134I	134	Missense	central	0	yes	25.807	0.000	EPSD;PhosphoSitePlus	TCGA	19.028	Loss
STE_STE20_PAKA_PAK1_ST	Q92934	BAD	Q13153	PAK1	S163	S167P	167	Missense	distal	4	no	16.941	19.291	EPSD	TCGA;COSMIC	19.028	Gain
STE_STE20_PAKA_PAK1_ST	Q92974	ARHGEF2	Q13153	PAK1	T103	A97V	97	Missense	distal	-6	no	19.427	18.641	EPSD	TCGA;ICGC;COSMIC	19.028	Loss
STE_STE20_PAKA_PAK1_ST	Q92974	ARHGEF2	Q13153	PAK1	T103	A96T	96	Missense	distal	-7	no	19.427	19.571	EPSD	TCGA	19.028	Up-regulation
STE_STE20_PAKA_PAK1_ST	Q92974	ARHGEF2	Q13153	PAK1	S122	P120L	120	Missense	proximal	-2	no	25.387	20.348	EPSD	TCGA;COSMIC	19.028	Down-regulation
STE_STE20_PAKA_PAK1_ST	Q92974	ARHGEF2	Q13153	PAK1	S122	P126S	126	Missense	distal	4	no	25.387	23.037	EPSD	TCGA;COSMIC	19.028	Down-regulation
STE_STE20_PAKA_PAK1_ST	Q92974	ARHGEF2	Q13153	PAK1	S122	R117Q	117	Missense	distal	-5	no	25.387	25.485	EPSD	TCGA;COSMIC	19.028	Up-regulation
STE_STE20_PAKA_PAK1_ST	Q92974	ARHGEF2	Q13153	PAK1	S133	R139H	139	Missense	distal	6	no	23.146	23.590	EPSD	TCGA;ICGC;COSMIC	19.028	Up-regulation
STE_STE20_PAKA_PAK1_ST	Q92974	ARHGEF2	Q13153	PAK1	S133	P126S	126	Missense	distal	-7	no	23.146	23.403	EPSD	TCGA;COSMIC	19.028	Up-regulation
STE_STE20_PAKA_PAK1_ST	Q92974	ARHGEF2	Q13153	PAK1	S133	S133F	133	Missense	central	0	yes	23.146	0.000	EPSD	TCGA;COSMIC	19.028	Loss
STE_STE20_PAKA_PAK1_ST	Q92974	ARHGEF2	Q13153	PAK1	S172	R168C	168	Missense	distal	-4	no	24.476	23.516	EPSD	TCGA;ICGC;COSMIC	19.028	Down-regulation
STE_STE20_PAKA_PAK1_ST	Q92974	ARHGEF2	Q13153	PAK1	S172	S174F	174	Missense	proximal	2	no	24.476	24.559	EPSD	TCGA;COSMIC;CCLE	19.028	Up-regulation
STE_STE20_PAKA_PAK1_ST	Q92974	ARHGEF2	Q13153	PAK1	T184	R183Q	183	Missense	proximal	-1	no	20.791	19.072	EPSD	TCGA;COSMIC	19.028	Down-regulation
STE_STE20_PAKA_PAK1_ST	Q92974	ARHGEF2	Q13153	PAK1	T184	T184I	184	Missense	central	0	yes	20.791	0.000	EPSD	TCGA;COSMIC	19.028	Loss
STE_STE20_PAKA_PAK1_ST	Q92974	ARHGEF2	Q13153	PAK1	S186	R183Q	183	Missense	distal	-3	no	21.191	12.467	EPSD	TCGA;COSMIC	19.028	Loss
STE_STE20_PAKA_PAK1_ST	Q92974	ARHGEF2	Q13153	PAK1	S186	T184I	184	Missense	proximal	-2	no	21.191	19.769	EPSD	TCGA;COSMIC	19.028	Down-regulation
STE_STE20_PAKA_PAK1_ST	Q92974	ARHGEF2	Q13153	PAK1	S309	C306Y	306	Missense	distal	-3	no	7.527	21.715	EPSD	TCGA;COSMIC	19.028	Gain
STE_STE20_PAKA_PAK1_ST	Q92974	ARHGEF2	Q13153	PAK1	T392	Q389H	389	Missense	distal	-3	no	19.749	22.401	EPSD	TCGA	19.028	Up-regulation
STE_STE20_PAKA_PAK1_ST	Q92974	ARHGEF2	Q13153	PAK1	T455	R452W	452	Missense	distal	-3	no	20.573	13.013	EPSD	TCGA;COSMIC	19.028	Loss
STE_STE20_PAKA_PAK1_ST	Q92974	ARHGEF2	Q13153	PAK1	T455	P456S	456	Missense	proximal	1	no	20.573	20.690	EPSD	TCGA;COSMIC	19.028	Up-regulation
STE_STE20_PAKA_PAK1_ST	Q92974	ARHGEF2	Q13153	PAK1	T455	P451T	451	Missense	distal	-4	no	20.573	21.139	EPSD	TCGA;COSMIC	19.028	Up-regulation
STE_STE20_PAKA_PAK1_ST	Q92974	ARHGEF2	Q13153	PAK1	S645	R650C	650	Missense	distal	5	no	19.400	19.423	EPSD	TCGA;COSMIC;CCLE	19.028	Up-regulation
STE_STE20_PAKA_PAK1_ST	Q92974	ARHGEF2	Q13153	PAK1	S645	L640V	640	Missense	distal	-5	no	19.400	19.142	EPSD	TCGA;COSMIC	19.028	Down-regulation
STE_STE20_PAKA_PAK1_ST	Q92974	ARHGEF2	Q13153	PAK1	S645	R638S	638	Missense	distal	-7	no	19.400	18.831	EPSD	TCGA;COSMIC	19.028	Loss
STE_STE20_PAKA_PAK1_ST	Q92974	ARHGEF2	Q13153	PAK1	S886	A889T	889	Missense	distal	3	no	31.453	30.207	PhosphoSitePlus;EPSD	TCGA;COSMIC	19.028	Down-regulation
STE_STE20_PAKA_PAK1_ST	Q92974	ARHGEF2	Q13153	PAK1	S886	D891N	891	Missense	distal	5	no	31.453	31.465	PhosphoSitePlus;EPSD	TCGA;COSMIC	19.028	Up-regulation
STE_STE20_PAKA_PAK1_ST	Q92974	ARHGEF2	Q13153	PAK1	S886	R885H	885	Missense	proximal	-1	no	31.453	28.646	PhosphoSitePlus;EPSD	TCGA;COSMIC	19.028	Down-regulation
STE_STE20_PAKA_PAK1_ST	Q92974	ARHGEF2	Q13153	PAK1	S886	R883W	883	Missense	distal	-3	no	31.453	23.893	PhosphoSitePlus;EPSD	TCGA;COSMIC	19.028	Down-regulation
STE_STE20_PAKA_PAK1_ST	Q92974	ARHGEF2	Q13153	PAK1	S896	S896R	896	Missense	central	0	yes	19.374	0.000	EPSD	TCGA;COSMIC	19.028	Loss
STE_STE20_PAKA_PAK1_ST	Q92974	ARHGEF2	Q13153	PAK1	S896	A889T	889	Missense	distal	-7	no	19.374	19.518	EPSD	TCGA;COSMIC	19.028	Up-regulation
STE_STE20_PAKA_PAK1_ST	Q92974	ARHGEF2	Q13153	PAK1	S896	D891N	891	Missense	distal	-5	no	19.374	19.528	EPSD	TCGA;COSMIC	19.028	Up-regulation
STE_STE20_PAKA_PAK1_ST	Q92974	ARHGEF2	Q13153	PAK1	S956	S953R	953	Missense	distal	-3	no	22.322	30.994	EPSD	TCGA;COSMIC	19.028	Up-regulation
STE_STE20_PAKA_PAK1_ST	Q92974	ARHGEF2	Q13153	PAK1	S956	R954H	954	Missense	proximal	-2	no	22.322	16.908	EPSD	TCGA;COSMIC	19.028	Loss
STE_STE20_PAKA_PAK1_ST	Q92974	ARHGEF2	Q13153	PAK1	S956	R954C	954	Missense	proximal	-2	no	22.322	9.602	EPSD	TCGA;COSMIC	19.028	Loss
STE_STE20_PAKA_PAK1_ST	Q92974	ARHGEF2	Q13153	PAK1	S956	S960N	960	Missense	distal	4	no	22.322	22.693	EPSD	TCGA;COSMIC	19.028	Up-regulation
STE_STE20_PAKA_PAK1_ST	Q92974	ARHGEF2	Q13153	PAK1	S960	R966T	966	Missense	distal	6	no	19.160	19.149	EPSD	TCGA;COSMIC	19.028	Down-regulation
STE_STE20_PAKA_PAK1_ST	Q92974	ARHGEF2	Q13153	PAK1	S960	S953R	953	Missense	distal	-7	no	19.160	19.729	EPSD	TCGA;COSMIC	19.028	Up-regulation
STE_STE20_PAKA_PAK1_ST	Q92974	ARHGEF2	Q13153	PAK1	S960	R954H	954	Missense	distal	-6	no	19.160	18.301	EPSD	TCGA;COSMIC	19.028	Loss
STE_STE20_PAKA_PAK1_ST	Q92974	ARHGEF2	Q13153	PAK1	S960	R954C	954	Missense	distal	-6	no	19.160	15.455	EPSD	TCGA;COSMIC	19.028	Loss
STE_STE20_PAKA_PAK1_ST	Q92974	ARHGEF2	Q13153	PAK1	S960	S960N	960	Missense	central	0	yes	19.160	0.000	EPSD	TCGA;COSMIC	19.028	Loss
STE_STE20_PAKA_PAK1_ST	Q13233	MAP3K1	Q13153	PAK1	S250	R248Q	248	Missense	proximal	-2	no	22.907	13.700	EPSD	TCGA;ICGC;COSMIC	19.028	Loss
STE_STE20_PAKA_PAK1_ST	Q13233	MAP3K1	Q13153	PAK1	S264	S258L	258	Missense	distal	-6	no	20.930	20.719	EPSD	TCGA;ICGC;COSMIC	19.028	Down-regulation
STE_STE20_PAKA_PAK1_ST	Q13233	MAP3K1	Q13153	PAK1	S275	Q280P	280	Missense	distal	5	no	28.994	29.025	EPSD	TCGA;ICGC;COSMIC	19.028	Up-regulation
STE_STE20_PAKA_PAK1_ST	Q13233	MAP3K1	Q13153	PAK1	S292	P287L	287	Missense	distal	-5	no	19.861	19.759	EPSD	TCGA;ICGC	19.028	Down-regulation
STE_STE20_PAKA_PAK1_ST	Q13233	MAP3K1	Q13153	PAK1	S397	Y392C	392	Missense	distal	-5	no	23.250	23.318	EPSD	TCGA;ICGC;COSMIC	19.028	Up-regulation
STE_STE20_PAKA_PAK1_ST	Q13233	MAP3K1	Q13153	PAK1	S397	R396H	396	Missense	proximal	-1	no	23.250	20.443	EPSD	TCGA;ICGC;COSMIC	19.028	Down-regulation
STE_STE20_PAKA_PAK1_ST	Q13233	MAP3K1	Q13153	PAK1	S398	Y392C	392	Missense	distal	-6	no	24.830	24.023	EPSD	TCGA;ICGC;COSMIC	19.028	Down-regulation
STE_STE20_PAKA_PAK1_ST	Q13233	MAP3K1	Q13153	PAK1	S398	R405H	405	Missense	distal	7	no	24.830	24.878	EPSD	TCGA;ICGC;GDSC;CCLE	19.028	Up-regulation
STE_STE20_PAKA_PAK1_ST	Q13233	MAP3K1	Q13153	PAK1	S398	R396H	396	Missense	proximal	-2	no	24.830	19.416	EPSD	TCGA;ICGC;COSMIC	19.028	Down-regulation
STE_STE20_PAKA_PAK1_ST	Q13233	MAP3K1	Q13153	PAK1	S796	R790M	790	Missense	distal	-6	no	20.444	18.044	EPSD	TCGA;ICGC;COSMIC	19.028	Loss
STE_STE20_PAKA_PAK1_ST	Q13233	MAP3K1	Q13153	PAK1	S796	A801T	801	Missense	distal	5	no	20.444	20.431	EPSD	TCGA;ICGC;COSMIC	19.028	Down-regulation
STE_STE20_PAKA_PAK1_ST	Q13233	MAP3K1	Q13153	PAK1	S1026	H1030Y	1030	Missense	distal	4	no	26.418	28.086	EPSD	TCGA;ICGC;COSMIC	19.028	Up-regulation
STE_STE20_PAKA_PAK1_ST	Q13233	MAP3K1	Q13153	PAK1	S1026	R1023C	1023	Missense	distal	-3	no	26.418	6.463	EPSD	TCGA;ICGC;COSMIC	19.028	Loss
STE_STE20_PAKA_PAK1_ST	Q13233	MAP3K1	Q13153	PAK1	S1397	A1396V	1396	Missense	proximal	-1	no	19.572	20.203	EPSD	TCGA;ICGC;COSMIC	19.028	Up-regulation
STE_STE20_PAKA_PAK1_ST	Q13233	MAP3K1	Q13153	PAK1	S1397	A1393G	1393	Missense	distal	-4	no	19.572	19.055	EPSD	TCGA;ICGC;COSMIC	19.028	Down-regulation
STE_STE20_PAKA_PAK1_ST	Q99426	TBCB	Q13153	PAK1	S29	E25Q	25	Missense	distal	-4	no	25.813	25.630	EPSD	TCGA;ICGC;COSMIC	19.028	Down-regulation
STE_STE20_PAKA_PAK1_ST	Q99426	TBCB	Q13153	PAK1	S29	F22L	22	Missense	distal	-7	no	25.813	26.107	EPSD	TCGA;ICGC;COSMIC	19.028	Up-regulation
STE_STE20_PAKA_PAK1_ST	Q99426	TBCB	Q13153	PAK1	S29	K26M	26	Missense	distal	-3	no	25.813	19.430	EPSD	TCGA;ICGC;COSMIC	19.028	Down-regulation
STE_STE20_PAKA_PAK1_ST	Q99426	TBCB	Q13153	PAK1	S29	R30H	30	Missense	proximal	1	no	25.813	25.551	EPSD	TCGA;ICGC;COSMIC	19.028	Down-regulation
STE_STE20_PAKA_PAK1_ST	Q99426	TBCB	Q13153	PAK1	T33	K26M	26	Missense	distal	-7	no	26.407	24.824	EPSD	TCGA;ICGC;COSMIC	19.028	Down-regulation
STE_STE20_PAKA_PAK1_ST	Q99426	TBCB	Q13153	PAK1	T33	R30H	30	Missense	distal	-3	no	26.407	20.336	EPSD	TCGA;ICGC;COSMIC	19.028	Down-regulation
STE_STE20_PAKA_PAK1_ST	Q99426	TBCB	Q13153	PAK1	S65	S65G	65	Missense	central	0	yes	21.424	0.000	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	19.028	Loss
STE_STE20_PAKA_PAK1_ST	Q99426	TBCB	Q13153	PAK1	S65	F63L	63	Missense	proximal	-2	no	21.424	18.478	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	19.028	Loss
STE_STE20_PAKA_PAK1_ST	Q99426	TBCB	Q13153	PAK1	S110	E105K	105	Missense	distal	-5	no	19.508	19.568	EPSD	TCGA	19.028	Up-regulation
STE_STE20_PAKA_PAK1_ST	Q99426	TBCB	Q13153	PAK1	S110	R103P	103	Missense	distal	-7	no	19.508	18.682	EPSD	TCGA;ICGC;COSMIC	19.028	Loss
STE_STE20_PAKA_PAK1_ST	Q99426	TBCB	Q13153	PAK1	S128	K126E	126	Missense	proximal	-2	no	20.192	17.709	PhosphoSitePlus;EPSD	TCGA	19.028	Loss
STE_STE20_PAKA_PAK1_ST	Q99661	KIF2C	Q13153	PAK1	S95	R93Q	93	Missense	proximal	-2	no	23.691	14.484	EPSD	TCGA;ICGC;COSMIC	19.028	Loss
STE_STE20_PAKA_PAK1_ST	Q99661	KIF2C	Q13153	PAK1	S95	P101S	101	Missense	distal	6	no	23.691	23.443	EPSD	TCGA;ICGC;COSMIC	19.028	Down-regulation
STE_STE20_PAKA_PAK1_ST	Q99661	KIF2C	Q13153	PAK1	S95	P101L	101	Missense	distal	6	no	23.691	23.715	EPSD	TCGA;ICGC;COSMIC	19.028	Up-regulation
STE_STE20_PAKA_PAK1_ST	Q99661	KIF2C	Q13153	PAK1	S111	R113C	113	Missense	proximal	2	no	26.002	27.020	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	19.028	Up-regulation
STE_STE20_PAKA_PAK1_ST	Q99661	KIF2C	Q13153	PAK1	S111	R108Q	108	Missense	distal	-3	no	26.002	17.278	EPSD;PhosphoSitePlus	TCGA;ICGC	19.028	Loss
STE_STE20_PAKA_PAK1_ST	Q99661	KIF2C	Q13153	PAK1	T116	R113C	113	Missense	distal	-3	no	25.853	5.898	EPSD	TCGA;ICGC;COSMIC	19.028	Loss
STE_STE20_PAKA_PAK1_ST	Q99661	KIF2C	Q13153	PAK1	T116	R121H	121	Missense	distal	5	no	25.853	25.866	EPSD	TCGA;ICGC;CCLE	19.028	Up-regulation
STE_STE20_PAKA_PAK1_ST	Q99661	KIF2C	Q13153	PAK1	T116	R121C	121	Missense	distal	5	no	25.853	25.876	EPSD	TCGA;ICGC;COSMIC;CCLE	19.028	Up-regulation
STE_STE20_PAKA_PAK1_ST	Q99661	KIF2C	Q13153	PAK1	S144	R140H	140	Missense	distal	-4	no	22.791	22.357	EPSD	TCGA;ICGC;COSMIC	19.028	Down-regulation
STE_STE20_PAKA_PAK1_ST	Q99661	KIF2C	Q13153	PAK1	S180	P184H	184	Missense	distal	4	no	23.427	21.336	EPSD	TCGA;COSMIC	19.028	Down-regulation
STE_STE20_PAKA_PAK1_ST	Q99661	KIF2C	Q13153	PAK1	S180	S181A	181	Missense	proximal	1	no	23.427	23.342	EPSD	TCGA;COSMIC	19.028	Down-regulation
STE_STE20_PAKA_PAK1_ST	Q99661	KIF2C	Q13153	PAK1	S180	S187P	187	Missense	distal	7	no	23.427	23.501	EPSD	TCGA;COSMIC	19.028	Up-regulation
STE_STE20_PAKA_PAK1_ST	Q99661	KIF2C	Q13153	PAK1	S180	S187L	187	Missense	distal	7	no	23.427	23.483	EPSD	TCGA;COSMIC	19.028	Up-regulation
STE_STE20_PAKA_PAK1_ST	Q99661	KIF2C	Q13153	PAK1	S192	S187P	187	Missense	distal	-5	no	28.284	29.146	PhosphoSitePlus;EPSD	TCGA;COSMIC	19.028	Up-regulation
STE_STE20_PAKA_PAK1_ST	Q99661	KIF2C	Q13153	PAK1	S192	S187L	187	Missense	distal	-5	no	28.284	29.044	PhosphoSitePlus;EPSD	TCGA;COSMIC	19.028	Up-regulation
STE_STE20_PAKA_PAK1_ST	Q99661	KIF2C	Q13153	PAK1	S551	G554A	554	Missense	distal	3	no	24.513	23.482	EPSD	TCGA;COSMIC	19.028	Down-regulation
STE_STE20_PAKA_PAK1_ST	Q99661	KIF2C	Q13153	PAK1	S551	I553M	553	Missense	proximal	2	no	24.513	25.389	EPSD	TCGA;COSMIC	19.028	Up-regulation
STE_STE20_PAKA_PAK1_ST	Q99661	KIF2C	Q13153	PAK1	S719	Q717H	717	Missense	proximal	-2	no	15.747	19.540	EPSD	TCGA;COSMIC	19.028	Gain
STE_STE20_PAKA_PAK1_ST	P18669	PGAM1	Q13153	PAK1	S118	P125Q	125	Missense	distal	7	no	23.471	23.299	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	19.028	Down-regulation
STE_STE20_PAKA_PAK1_ST	P18669	PGAM1	Q13153	PAK1	S118	P125L	125	Missense	distal	7	no	23.471	23.452	EPSD;PhosphoSitePlus	TCGA	19.028	Down-regulation
STE_STE20_PAKA_PAK1_ST	P18669	PGAM1	Q13153	PAK1	T146	Q149E	149	Missense	distal	3	no	19.034	18.608	EPSD	TCGA;ICGC;COSMIC	19.028	Loss
STE_STE20_PAKA_PAK1_ST	P18669	PGAM1	Q13153	PAK1	T146	R140H	140	Missense	distal	-6	no	19.034	18.175	EPSD	TCGA;ICGC;COSMIC;GDSC;CCLE	19.028	Loss
STE_STE20_PAKA_PAK1_ST	P18669	PGAM1	Q13153	PAK1	T146	R141M	141	Missense	distal	-5	no	19.034	19.927	EPSD	TCGA;ICGC;COSMIC	19.028	Up-regulation
STE_STE20_PAKA_PAK1_ST	P18669	PGAM1	Q13153	PAK1	T146	E147K	147	Missense	proximal	1	no	19.034	18.904	EPSD	TCGA;ICGC;COSMIC	19.028	Loss
STE_STE20_PAKA_PAK1_ST	P18669	PGAM1	Q13153	PAK1	T146	D139Y	139	Missense	distal	-7	no	19.034	17.785	EPSD	TCGA;COSMIC	19.028	Loss
STE_STE20_PAKA_PAK1_ST	P78545	ELF3	Q13153	PAK1	S58	E55K	55	Missense	distal	-3	no	6.533	20.325	EPSD	TCGA;COSMIC	19.028	Gain
STE_STE20_PAKA_PAK1_ST	P78545	ELF3	Q13153	PAK1	S207	S204C	204	Missense	distal	-3	no	22.411	11.127	PhosphoSitePlus	TCGA;ICGC;COSMIC	19.028	Loss
STE_STE20_PAKA_PAK1_ST	P78545	ELF3	Q13153	PAK1	S254	R251P	251	Missense	distal	-3	no	24.714	19.031	EPSD	TCGA;ICGC;COSMIC	19.028	Down-regulation
STE_STE20_PAKA_PAK1_ST	P78545	ELF3	Q13153	PAK1	S254	K252N	252	Missense	proximal	-2	no	24.714	23.157	EPSD	TCGA;ICGC;COSMIC	19.028	Down-regulation
STE_STE20_PAKA_PAK1_ST	P78545	ELF3	Q13153	PAK1	S254	R247Q	247	Missense	distal	-7	no	24.714	24.191	EPSD	TCGA;ICGC;COSMIC	19.028	Down-regulation
STE_STE20_PAKA_PAK1_ST	P78545	ELF3	Q13153	PAK1	S254	P250R	250	Missense	distal	-4	no	24.714	25.233	EPSD	TCGA;ICGC;COSMIC	19.028	Up-regulation
STE_STE20_PAKA_PAK1_ST	P78545	ELF3	Q13153	PAK1	S254	R251L	251	Missense	distal	-3	no	24.714	18.224	EPSD	TCGA;ICGC;COSMIC	19.028	Loss
STE_STE20_PAKA_PAK1_ST	P78545	ELF3	Q13153	PAK1	S254	P250S	250	Missense	distal	-4	no	24.714	24.767	EPSD	TCGA;ICGC	19.028	Up-regulation
STE_STE20_PAKA_PAK1_ST	P46108	CRK	Q13153	PAK1	S194	V187I	187	Missense	distal	-7	no	20.158	20.935	EPSD	TCGA;ICGC;COSMIC	19.028	Up-regulation
STE_STE20_PAKA_PAK1_ST	P35222	CTNNB1	Q13153	PAK1	S47	S45F	45	Missense	proximal	-2	no	18.676	21.210	EPSD	TCGA;COSMIC;GDSC;CCLE	19.028	Gain
STE_STE20_PAKA_PAK1_ST	P35222	CTNNB1	Q13153	PAK1	S47	S45P	45	Missense	proximal	-2	no	18.676	23.303	EPSD	TCGA;COSMIC;CCLE	19.028	Gain
STE_STE20_PAKA_PAK1_ST	P35222	CTNNB1	Q13153	PAK1	S47	S45Y	45	Missense	proximal	-2	no	18.676	22.488	EPSD	TCGA;COSMIC	19.028	Gain
STE_STE20_PAKA_PAK1_ST	P35222	CTNNB1	Q13153	PAK1	S184	R185G	185	Missense	proximal	1	no	20.045	19.564	EPSD	TCGA;COSMIC	19.028	Down-regulation
STE_STE20_PAKA_PAK1_ST	P35222	CTNNB1	Q13153	PAK1	T332	E334A	334	Missense	proximal	2	no	20.339	21.216	EPSD	TCGA;COSMIC	19.028	Up-regulation
STE_STE20_PAKA_PAK1_ST	P35222	CTNNB1	Q13153	PAK1	T332	K335T	335	Missense	distal	3	no	20.339	20.473	EPSD	TCGA;COSMIC	19.028	Up-regulation
STE_STE20_PAKA_PAK1_ST	P35222	CTNNB1	Q13153	PAK1	T332	K335I	335	Missense	distal	3	no	20.339	21.544	EPSD	TCGA;COSMIC	19.028	Up-regulation
STE_STE20_PAKA_PAK1_ST	P35222	CTNNB1	Q13153	PAK1	T332	Y333F	333	Missense	proximal	1	no	20.339	20.689	EPSD	TCGA;COSMIC	19.028	Up-regulation
STE_STE20_PAKA_PAK1_ST	P35222	CTNNB1	Q13153	PAK1	T332	M328I	328	Missense	distal	-4	no	20.339	20.770	EPSD	TCGA;COSMIC	19.028	Up-regulation
STE_STE20_PAKA_PAK1_ST	P35222	CTNNB1	Q13153	PAK1	T332	T339N	339	Missense	distal	7	no	20.339	20.598	EPSD	TCGA;COSMIC	19.028	Up-regulation
STE_STE20_PAKA_PAK1_ST	P35222	CTNNB1	Q13153	PAK1	T332	E334K	334	Missense	proximal	2	no	20.339	20.642	EPSD	TCGA;COSMIC;GDSC;CCLE	19.028	Up-regulation
STE_STE20_PAKA_PAK1_ST	P35222	CTNNB1	Q13153	PAK1	T332	L336P	336	Missense	distal	4	no	20.339	21.896	EPSD	TCGA;COSMIC	19.028	Up-regulation
STE_STE20_PAKA_PAK1_ST	P35222	CTNNB1	Q13153	PAK1	S552	M553V	553	Missense	proximal	1	no	29.381	29.296	EPSD	TCGA;COSMIC	19.028	Down-regulation
STE_STE20_PAKA_PAK1_ST	P35222	CTNNB1	Q13153	PAK1	S675	S681F	681	Missense	distal	6	no	27.663	28.039	PhosphoSitePlus	TCGA	19.028	Up-regulation
STE_STE20_PAKA_PAK1_ST	Q14247	CTTN	Q13153	PAK1	S117	Q114P	114	Missense	distal	-3	no	17.252	20.293	EPSD	TCGA;ICGC;COSMIC	19.028	Gain
STE_STE20_PAKA_PAK1_ST	Q14247	CTTN	Q13153	PAK1	S150	G143R	143	Missense	distal	-7	no	18.368	19.875	EPSD	TCGA;ICGC;COSMIC	19.028	Gain
STE_STE20_PAKA_PAK1_ST	Q14247	CTTN	Q13153	PAK1	S155	Y162C	162	Missense	distal	7	no	21.265	21.167	EPSD	TCGA;ICGC;COSMIC	19.028	Down-regulation
STE_STE20_PAKA_PAK1_ST	Q14247	CTTN	Q13153	PAK1	S155	S155F	155	Missense	central	0	yes	21.265	0.000	EPSD	TCGA;ICGC;COSMIC	19.028	Loss
STE_STE20_PAKA_PAK1_ST	Q14247	CTTN	Q13153	PAK1	S156	Y162C	162	Missense	distal	6	no	20.434	20.161	EPSD	TCGA;ICGC;COSMIC	19.028	Down-regulation
STE_STE20_PAKA_PAK1_ST	Q14247	CTTN	Q13153	PAK1	S156	S155F	155	Missense	proximal	-1	no	20.434	21.231	EPSD	TCGA;ICGC;COSMIC	19.028	Up-regulation
STE_STE20_PAKA_PAK1_ST	Q14247	CTTN	Q13153	PAK1	S187	R189K	189	Missense	proximal	2	no	20.831	21.548	EPSD	TCGA;ICGC;COSMIC	19.028	Up-regulation
STE_STE20_PAKA_PAK1_ST	Q14247	CTTN	Q13153	PAK1	S187	S192F	192	Missense	distal	5	no	20.831	20.839	EPSD	TCGA;ICGC;COSMIC	19.028	Up-regulation
STE_STE20_PAKA_PAK1_ST	Q14247	CTTN	Q13153	PAK1	S187	H185L	185	Missense	proximal	-2	no	20.831	17.681	EPSD	TCGA;ICGC;COSMIC	19.028	Loss
STE_STE20_PAKA_PAK1_ST	Q14247	CTTN	Q13153	PAK1	S192	R189K	189	Missense	distal	-3	no	22.007	20.820	EPSD	TCGA;ICGC;COSMIC	19.028	Down-regulation
STE_STE20_PAKA_PAK1_ST	Q14247	CTTN	Q13153	PAK1	S192	S192F	192	Missense	central	0	yes	22.007	0.000	EPSD	TCGA;ICGC;COSMIC	19.028	Loss
STE_STE20_PAKA_PAK1_ST	Q14247	CTTN	Q13153	PAK1	S192	H185L	185	Missense	distal	-7	no	22.007	22.085	EPSD	TCGA;ICGC;COSMIC	19.028	Up-regulation
STE_STE20_PAKA_PAK1_ST	Q14247	CTTN	Q13153	PAK1	S224	H222R	222	Missense	proximal	-2	no	20.281	25.694	EPSD	TCGA;ICGC;COSMIC	19.028	Up-regulation
STE_STE20_PAKA_PAK1_ST	Q14247	CTTN	Q13153	PAK1	S224	T219M	219	Missense	distal	-5	no	20.281	20.716	EPSD	TCGA;ICGC;COSMIC	19.028	Up-regulation
STE_STE20_PAKA_PAK1_ST	Q14247	CTTN	Q13153	PAK1	T267	G270S	270	Missense	distal	3	no	20.260	17.516	EPSD	TCGA;COSMIC	19.028	Loss
STE_STE20_PAKA_PAK1_ST	Q14247	CTTN	Q13153	PAK1	T267	K272R	272	Missense	distal	5	no	20.260	20.251	EPSD	TCGA;COSMIC	19.028	Down-regulation
STE_STE20_PAKA_PAK1_ST	P49023	PXN	Q13153	PAK1	S119	Q124H	124	Missense	distal	5	no	19.848	19.863	EPSD	TCGA;COSMIC	19.028	Up-regulation
STE_STE20_PAKA_PAK1_ST	P49023	PXN	Q13153	PAK1	S135	M134I	134	Missense	proximal	-1	no	19.014	20.480	EPSD	TCGA;COSMIC	19.028	Gain
STE_STE20_PAKA_PAK1_ST	P49023	PXN	Q13153	PAK1	S135	L138M	138	Missense	distal	3	no	19.014	19.110	EPSD	TCGA;COSMIC	19.028	Gain
STE_STE20_PAKA_PAK1_ST	P49023	PXN	Q13153	PAK1	S250	V248I	248	Missense	proximal	-2	no	21.313	20.587	EPSD	TCGA;COSMIC;CCLE	19.028	Down-regulation
STE_STE20_PAKA_PAK1_ST	P49023	PXN	Q13153	PAK1	S250	R247H	247	Missense	distal	-3	no	21.313	15.241	EPSD	TCGA;COSMIC	19.028	Loss
STE_STE20_PAKA_PAK1_ST	Q9Y2X7	GIT1	Q13153	PAK1	S46	R52H	52	Missense	distal	6	no	22.067	22.511	EPSD	TCGA;ICGC	19.028	Up-regulation
STE_STE20_PAKA_PAK1_ST	Q9Y2X7	GIT1	Q13153	PAK1	S46	R39Q	39	Missense	distal	-7	no	22.067	21.544	EPSD	TCGA;ICGC;COSMIC	19.028	Down-regulation
STE_STE20_PAKA_PAK1_ST	Q9Y2X7	GIT1	Q13153	PAK1	S54	R52H	52	Missense	proximal	-2	no	19.375	13.961	EPSD	TCGA;ICGC	19.028	Loss
STE_STE20_PAKA_PAK1_ST	Q9Y2X7	GIT1	Q13153	PAK1	S54	L61M	61	Missense	distal	7	no	19.375	19.474	EPSD	TCGA;ICGC	19.028	Up-regulation
STE_STE20_PAKA_PAK1_ST	Q9Y2X7	GIT1	Q13153	PAK1	S134	G127E	127	Missense	distal	-7	no	19.817	21.432	EPSD	TCGA;ICGC	19.028	Up-regulation
STE_STE20_PAKA_PAK1_ST	Q9Y2X7	GIT1	Q13153	PAK1	S134	S140N	140	Missense	distal	6	no	19.817	20.001	EPSD	TCGA;ICGC;COSMIC	19.028	Up-regulation
STE_STE20_PAKA_PAK1_ST	Q9Y2X7	GIT1	Q13153	PAK1	S134	D132Y	132	Missense	proximal	-2	no	19.817	21.812	EPSD	TCGA;ICGC;COSMIC	19.028	Up-regulation
STE_STE20_PAKA_PAK1_ST	Q9Y2X7	GIT1	Q13153	PAK1	S154	N160D	160	Missense	distal	6	no	24.221	24.076	EPSD	TCGA;ICGC;COSMIC	19.028	Down-regulation
STE_STE20_PAKA_PAK1_ST	Q9Y2X7	GIT1	Q13153	PAK1	S410	R407C	407	Missense	distal	-3	no	20.629	0.673	EPSD	TCGA;COSMIC	19.028	Loss
STE_STE20_PAKA_PAK1_ST	P53350	PLK1	Q13153	PAK1	S49	R48H	48	Missense	proximal	-1	no	21.077	18.269	PhosphoSitePlus	TCGA;ICGC;COSMIC	19.028	Loss
STE_STE20_PAKA_PAK1_ST	P53350	PLK1	Q13153	PAK1	S49	D46N	46	Missense	distal	-3	no	21.077	19.002	PhosphoSitePlus	TCGA;ICGC;COSMIC	19.028	Loss
STE_STE20_PAKA_PAK1_ST	P53350	PLK1	Q13153	PAK1	S137	R134H	134	Missense	distal	-3	no	26.095	20.023	EPSD	TCGA;ICGC	19.028	Down-regulation
STE_STE20_PAKA_PAK1_ST	P53350	PLK1	Q13153	PAK1	T210	G213V	213	Missense	distal	3	no	21.693	20.406	EPSD	TCGA;ICGC	19.028	Down-regulation
STE_STE20_PAKA_PAK1_ST	P53350	PLK1	Q13153	PAK1	T210	K208E	208	Missense	proximal	-2	no	21.693	19.211	EPSD	TCGA;ICGC;COSMIC	19.028	Down-regulation
STE_STE20_PAKA_PAK1_ST	P53350	PLK1	Q13153	PAK1	T210	D204G	204	Missense	distal	-6	no	21.693	21.195	EPSD	TCGA;ICGC;COSMIC	19.028	Down-regulation
STE_STE20_PAKA_PAK1_ST	P53350	PLK1	Q13153	PAK1	S326	L319M	319	Missense	distal	-7	no	24.459	23.529	EPSD	TCGA;ICGC;COSMIC	19.028	Down-regulation
STE_STE20_PAKA_PAK1_ST	P53350	PLK1	Q13153	PAK1	S326	S326L	326	Missense	central	0	yes	24.459	0.000	EPSD	TCGA;ICGC;COSMIC;CCLE	19.028	Loss
STE_STE20_PAKA_PAK1_ST	P53350	PLK1	Q13153	PAK1	S326	P323L	323	Missense	distal	-3	no	24.459	23.651	EPSD	TCGA;ICGC;COSMIC	19.028	Down-regulation
STE_STE20_PAKA_PAK1_ST	P53350	PLK1	Q13153	PAK1	T341	S335C	335	Missense	distal	-6	no	23.847	22.152	EPSD	TCGA;ICGC;COSMIC	19.028	Down-regulation
STE_STE20_PAKA_PAK1_ST	P53350	PLK1	Q13153	PAK1	T341	R337W	337	Missense	distal	-4	no	23.847	22.862	EPSD	TCGA;ICGC;COSMIC	19.028	Down-regulation
STE_STE20_PAKA_PAK1_ST	P53350	PLK1	Q13153	PAK1	T341	V342F	342	Missense	proximal	1	no	23.847	24.184	EPSD	TCGA;ICGC	19.028	Up-regulation
STE_STE20_PAKA_PAK1_ST	P53350	PLK1	Q13153	PAK1	T459	R456C	456	Missense	distal	-3	no	20.475	0.519	EPSD	TCGA;ICGC;COSMIC	19.028	Loss
STE_STE20_PAKA_PAK1_ST	P53350	PLK1	Q13153	PAK1	T459	D457G	457	Missense	proximal	-2	no	20.475	17.247	EPSD	TCGA;ICGC;COSMIC	19.028	Loss
STE_STE20_PAKA_PAK1_ST	P53350	PLK1	Q13153	PAK1	T459	R456H	456	Missense	distal	-3	no	20.475	14.403	EPSD	TCGA;ICGC;COSMIC	19.028	Loss
STE_STE20_PAKA_PAK1_ST	P53350	PLK1	Q13153	PAK1	T459	G458D	458	Missense	proximal	-1	no	20.475	22.833	EPSD	TCGA;ICGC;COSMIC	19.028	Up-regulation
STE_STE20_PAKA_PAK1_ST	P53350	PLK1	Q13153	PAK1	T459	V465M	465	Missense	distal	6	no	20.475	20.719	EPSD	TCGA;ICGC;COSMIC	19.028	Up-regulation
STE_STE20_PAKA_PAK1_ST	P53350	PLK1	Q13153	PAK1	S565	R560H	560	Missense	distal	-5	no	24.734	25.180	EPSD	TCGA;ICGC;COSMIC	19.028	Up-regulation
STE_STE20_PAKA_PAK1_ST	P24844	MYL9	Q13153	PAK1	S20	R17W	17	Missense	distal	-3	no	23.883	16.322	PhosphoSitePlus	TCGA;ICGC;COSMIC	19.028	Loss
STE_STE20_PAKA_PAK1_ST	P24844	MYL9	Q13153	PAK1	T135	E137K	137	Missense	proximal	2	no	20.439	20.742	EPSD	TCGA;COSMIC	19.028	Up-regulation
STE_STE20_PAKA_PAK1_ST	P24844	MYL9	Q13153	PAK1	T135	R133H	133	Missense	proximal	-2	no	20.439	15.025	EPSD	TCGA;COSMIC	19.028	Loss
STE_STE20_PAKA_PAK1_ST	P24844	MYL9	Q13153	PAK1	T135	M130V	130	Missense	distal	-5	no	20.439	20.078	EPSD	TCGA;ICGC;COSMIC;CCLE	19.028	Down-regulation
STE_STE20_PAKA_PAK1_ST	P24844	MYL9	Q13153	PAK1	T135	T129I	129	Missense	distal	-6	no	20.439	18.390	EPSD	TCGA;ICGC;COSMIC	19.028	Loss
STE_STE20_PAKA_PAK1_ST	P24844	MYL9	Q13153	PAK1	T135	E137D	137	Missense	proximal	2	no	20.439	20.748	EPSD	TCGA	19.028	Up-regulation
STE_STE20_PAKA_PAK1_ST	P21333	FLNA	Q13153	PAK1	S204	L209M	209	Missense	distal	5	no	19.434	19.452	EPSD	TCGA;ICGC;COSMIC	19.028	Up-regulation
STE_STE20_PAKA_PAK1_ST	P21333	FLNA	Q13153	PAK1	S204	P207L	207	Missense	distal	3	no	19.434	18.848	EPSD	TCGA;ICGC;COSMIC	19.028	Loss
STE_STE20_PAKA_PAK1_ST	P21333	FLNA	Q13153	PAK1	T341	K338Q	338	Missense	distal	-3	no	19.929	12.391	EPSD	TCGA;ICGC;COSMIC	19.028	Loss
STE_STE20_PAKA_PAK1_ST	P21333	FLNA	Q13153	PAK1	T341	P348S	348	Missense	distal	7	no	19.929	19.854	EPSD	TCGA;ICGC;COSMIC	19.028	Down-regulation
STE_STE20_PAKA_PAK1_ST	P21333	FLNA	Q13153	PAK1	S343	K338Q	338	Missense	distal	-5	no	28.456	28.408	EPSD	TCGA;ICGC;COSMIC	19.028	Down-regulation
STE_STE20_PAKA_PAK1_ST	P21333	FLNA	Q13153	PAK1	S343	P348S	348	Missense	distal	5	no	28.456	28.428	EPSD	TCGA;ICGC;COSMIC	19.028	Down-regulation
STE_STE20_PAKA_PAK1_ST	P21333	FLNA	Q13153	PAK1	S440	R437Q	437	Missense	distal	-3	no	20.064	11.340	EPSD	TCGA;ICGC;COSMIC	19.028	Loss
STE_STE20_PAKA_PAK1_ST	P21333	FLNA	Q13153	PAK1	S440	R443H	443	Missense	distal	3	no	20.064	20.318	EPSD	TCGA;ICGC	19.028	Up-regulation
STE_STE20_PAKA_PAK1_ST	P21333	FLNA	Q13153	PAK1	S440	R443C	443	Missense	distal	3	no	20.064	21.060	EPSD	TCGA;ICGC;COSMIC	19.028	Up-regulation
STE_STE20_PAKA_PAK1_ST	P21333	FLNA	Q13153	PAK1	T572	E567K	567	Missense	distal	-5	no	19.568	19.629	EPSD	TCGA;ICGC;COSMIC	19.028	Up-regulation
STE_STE20_PAKA_PAK1_ST	P21333	FLNA	Q13153	PAK1	T572	P565L	565	Missense	distal	-7	no	19.568	19.123	EPSD	TCGA;ICGC;COSMIC	19.028	Down-regulation
STE_STE20_PAKA_PAK1_ST	P21333	FLNA	Q13153	PAK1	T572	E573K	573	Missense	proximal	1	no	19.568	19.439	EPSD	TCGA;ICGC;COSMIC	19.028	Down-regulation
STE_STE20_PAKA_PAK1_ST	P21333	FLNA	Q13153	PAK1	S1279	R1283W	1283	Missense	distal	4	no	17.641	19.758	EPSD	TCGA;ICGC;COSMIC	19.028	Gain
STE_STE20_PAKA_PAK1_ST	P21333	FLNA	Q13153	PAK1	T1286	R1283W	1283	Missense	distal	-3	no	19.276	11.716	EPSD	TCGA;ICGC;COSMIC	19.028	Loss
STE_STE20_PAKA_PAK1_ST	P21333	FLNA	Q13153	PAK1	T1286	P1291L	1291	Missense	distal	5	no	19.276	19.262	EPSD	TCGA;ICGC;COSMIC	19.028	Down-regulation
STE_STE20_PAKA_PAK1_ST	P21333	FLNA	Q13153	PAK1	T1286	A1282T	1282	Missense	distal	-4	no	19.276	19.693	EPSD	TCGA;ICGC	19.028	Up-regulation
STE_STE20_PAKA_PAK1_ST	P21333	FLNA	Q13153	PAK1	T1305	S1301L	1301	Missense	distal	-4	no	19.455	19.608	EPSD	TCGA;ICGC;COSMIC	19.028	Up-regulation
STE_STE20_PAKA_PAK1_ST	P21333	FLNA	Q13153	PAK1	T1305	T1307N	1307	Missense	proximal	2	no	19.455	20.541	EPSD	TCGA	19.028	Up-regulation
STE_STE20_PAKA_PAK1_ST	P21333	FLNA	Q13153	PAK1	S1812	A1816T	1816	Missense	distal	4	no	22.366	21.023	EPSD	TCGA	19.028	Down-regulation
STE_STE20_PAKA_PAK1_ST	P21333	FLNA	Q13153	PAK1	S1812	R1809W	1809	Missense	distal	-3	no	22.366	14.806	EPSD	TCGA	19.028	Loss
STE_STE20_PAKA_PAK1_ST	P21333	FLNA	Q13153	PAK1	S1812	G1813C	1813	Missense	proximal	1	no	22.366	22.404	EPSD	TCGA;COSMIC	19.028	Up-regulation
STE_STE20_PAKA_PAK1_ST	P21333	FLNA	Q13153	PAK1	S1957	S1961P	1961	Missense	distal	4	no	16.811	19.161	EPSD	TCGA;COSMIC	19.028	Gain
STE_STE20_PAKA_PAK1_ST	P21333	FLNA	Q13153	PAK1	S1961	M1958I	1958	Missense	distal	-3	no	19.051	11.154	EPSD	TCGA;ICGC;COSMIC	19.028	Loss
STE_STE20_PAKA_PAK1_ST	P21333	FLNA	Q13153	PAK1	S1961	S1961P	1961	Missense	central	0	yes	19.051	0.000	EPSD	TCGA;COSMIC	19.028	Loss
STE_STE20_PAKA_PAK1_ST	P21333	FLNA	Q13153	PAK1	S1961	R1959C	1959	Missense	proximal	-2	no	19.051	6.331	EPSD	TCGA;COSMIC;GDSC	19.028	Loss
STE_STE20_PAKA_PAK1_ST	P21333	FLNA	Q13153	PAK1	S1961	M1958L	1958	Missense	distal	-3	no	19.051	20.130	EPSD	TCGA;COSMIC	19.028	Up-regulation
STE_STE20_PAKA_PAK1_ST	P21333	FLNA	Q13153	PAK1	S1967	I1973F	1973	Missense	distal	6	no	21.788	21.949	EPSD	TCGA;COSMIC	19.028	Up-regulation
STE_STE20_PAKA_PAK1_ST	P21333	FLNA	Q13153	PAK1	S1967	I1971M	1971	Missense	distal	4	no	21.788	21.993	EPSD	TCGA;COSMIC	19.028	Up-regulation
STE_STE20_PAKA_PAK1_ST	P21333	FLNA	Q13153	PAK1	S1967	S1961P	1961	Missense	distal	-6	no	21.788	21.731	EPSD	TCGA;COSMIC	19.028	Down-regulation
STE_STE20_PAKA_PAK1_ST	P21333	FLNA	Q13153	PAK1	S2032	V2030M	2030	Missense	proximal	-2	no	17.957	19.278	EPSD	TCGA;COSMIC	19.028	Gain
STE_STE20_PAKA_PAK1_ST	P21333	FLNA	Q13153	PAK1	S2152	S2152L	2152	Missense	central	0	yes	22.847	0.000	PhosphoSitePlus;EPSD	TCGA;COSMIC	19.028	Loss
STE_STE20_PAKA_PAK1_ST	P21333	FLNA	Q13153	PAK1	S2152	R2148S	2148	Missense	distal	-4	no	22.847	22.381	PhosphoSitePlus;EPSD	TCGA;COSMIC	19.028	Down-regulation
STE_STE20_PAKA_PAK1_ST	P21333	FLNA	Q13153	PAK1	S2180	Q2177H	2177	Missense	distal	-3	no	17.418	20.070	EPSD	TCGA;COSMIC	19.028	Gain
STE_STE20_PAKA_PAK1_ST	P21333	FLNA	Q13153	PAK1	S2260	E2258K	2258	Missense	proximal	-2	no	19.181	21.664	EPSD	TCGA;COSMIC	19.028	Up-regulation
STE_STE20_PAKA_PAK1_ST	P21333	FLNA	Q13153	PAK1	S2292	R2288H	2288	Missense	distal	-4	no	23.298	22.864	EPSD;PhosphoSitePlus	TCGA;COSMIC	19.028	Down-regulation
STE_STE20_PAKA_PAK1_ST	P21333	FLNA	Q13153	PAK1	S2292	K2289N	2289	Missense	distal	-3	no	23.298	15.454	EPSD;PhosphoSitePlus	TCGA	19.028	Loss
STE_STE20_PAKA_PAK1_ST	P21333	FLNA	Q13153	PAK1	T2336	R2334H	2334	Missense	proximal	-2	no	27.160	21.746	EPSD	TCGA;COSMIC;GDSC;CCLE	19.028	Down-regulation
STE_STE20_PAKA_PAK1_ST	P21333	FLNA	Q13153	PAK1	T2336	E2342K	2342	Missense	distal	6	no	27.160	27.475	EPSD	TCGA	19.028	Up-regulation
STE_STE20_PAKA_PAK1_ST	P21333	FLNA	Q13153	PAK1	T2336	A2332T	2332	Missense	distal	-4	no	27.160	27.576	EPSD	TCGA;COSMIC	19.028	Up-regulation
STE_STE20_PAKA_PAK1_ST	P21333	FLNA	Q13153	PAK1	S2370	S2372L	2372	Missense	proximal	2	no	24.033	24.846	EPSD;PhosphoSitePlus	TCGA;COSMIC	19.028	Up-regulation
STE_STE20_PAKA_PAK1_ST	P21333	FLNA	Q13153	PAK1	S2370	H2369Y	2369	Missense	proximal	-1	no	24.033	24.880	EPSD;PhosphoSitePlus	TCGA;COSMIC	19.028	Up-regulation
STE_STE20_PAKA_PAK1_ST	P21333	FLNA	Q13153	PAK1	S2370	A2363V	2363	Missense	distal	-7	no	24.033	22.602	EPSD;PhosphoSitePlus	TCGA;COSMIC	19.028	Down-regulation
STE_STE20_PAKA_PAK1_ST	P21333	FLNA	Q13153	PAK1	S2370	P2371L	2371	Missense	proximal	1	no	24.033	24.320	EPSD;PhosphoSitePlus	TCGA;COSMIC	19.028	Up-regulation
STE_STE20_PAKA_PAK1_ST	P21333	FLNA	Q13153	PAK1	S2370	A2374S	2374	Missense	distal	4	no	24.033	23.057	EPSD;PhosphoSitePlus	TCGA;COSMIC	19.028	Down-regulation
STE_STE20_PAKA_PAK1_ST	P21333	FLNA	Q13153	PAK1	S2523	S2526I	2526	Missense	distal	3	no	17.919	19.457	EPSD	TCGA	19.028	Gain
STE_STE20_PAKA_PAK1_ST	P21333	FLNA	Q13153	PAK1	S2615	R2612W	2612	Missense	distal	-3	no	20.003	12.442	EPSD	TCGA;GDSC	19.028	Loss
STE_STE20_PAKA_PAK1_ST	P21333	FLNA	Q13153	PAK1	S2615	V2609M	2609	Missense	distal	-6	no	20.003	19.342	EPSD	TCGA;COSMIC;GDSC;CCLE	19.028	Down-regulation
STE_STE20_PAKA_PAK1_ST	P21333	FLNA	Q13153	PAK1	S2615	S2617P	2617	Missense	proximal	2	no	20.003	20.648	EPSD	TCGA;COSMIC	19.028	Up-regulation
STE_STE20_PAKA_PAK1_ST	O43623	SNAI2	Q13153	PAK1	S100	K97M	97	Missense	distal	-3	no	20.384	14.001	EPSD	TCGA;ICGC;COSMIC	19.028	Loss
STE_STE20_PAKA_PAK1_ST	O43623	SNAI2	Q13153	PAK1	S100	D98Y	98	Missense	proximal	-2	no	20.384	22.379	EPSD	TCGA;ICGC;COSMIC	19.028	Up-regulation
STE_STE20_PAKA_PAK1_ST	O43623	SNAI2	Q13153	PAK1	S251	F250L	250	Missense	proximal	-1	no	20.662	20.813	PhosphoSitePlus	TCGA;ICGC	19.028	Up-regulation
STE_STE20_PAKA_PAK1_ST	O43623	SNAI2	Q13153	PAK1	S251	S247F	247	Missense	distal	-4	no	20.662	20.944	PhosphoSitePlus	TCGA	19.028	Up-regulation
STE_STE20_PAKA_PAK1_ST	O43623	SNAI2	Q13153	PAK1	S251	T249P	249	Missense	proximal	-2	no	20.662	22.000	PhosphoSitePlus	TCGA;ICGC;COSMIC	19.028	Up-regulation
STE_STE20_PAKA_PAK1_ST	O95863	SNAI1	Q13153	PAK1	S11	V7A	7	Missense	distal	-4	no	20.424	20.613	EPSD	TCGA;ICGC;COSMIC	19.028	Up-regulation
STE_STE20_PAKA_PAK1_ST	O95863	SNAI1	Q13153	PAK1	S246	R243Q	243	Missense	distal	-3	no	20.834	12.110	PhosphoSitePlus	TCGA;ICGC;COSMIC	19.028	Loss
STE_STE20_PAKA_PAK1_ST	O95863	SNAI1	Q13153	PAK1	S246	R247P	247	Missense	proximal	1	no	20.834	20.315	PhosphoSitePlus	TCGA;ICGC;COSMIC	19.028	Down-regulation
STE_STE20_PAKA_PAK1_ST	O95863	SNAI1	Q13153	PAK1	S246	C241F	241	Missense	distal	-5	no	20.834	20.539	PhosphoSitePlus	TCGA;ICGC;COSMIC	19.028	Down-regulation
STE_STE20_PAKA_PAK1_ST	P52565	ARHGDIA	Q13153	PAK1	S101	S96R	96	Missense	distal	-5	no	23.937	23.908	EPSD;PhosphoSitePlus	TCGA;ICGC	19.028	Down-regulation
STE_STE20_PAKA_PAK1_ST	P52565	ARHGDIA	Q13153	PAK1	S174	R180H	180	Missense	distal	6	no	22.183	22.627	PhosphoSitePlus;EPSD	TCGA;COSMIC	19.028	Up-regulation
STE_STE20_PAKA_PAK1_ST	P52565	ARHGDIA	Q13153	PAK1	S174	I177M	177	Missense	distal	3	no	22.183	22.535	PhosphoSitePlus;EPSD	TCGA;COSMIC	19.028	Up-regulation
STE_STE20_PAKA_PAK1_ST	Q15365	PCBP1	Q13153	PAK1	S43	S50L	50	Missense	distal	7	no	18.976	19.032	EPSD	TCGA;ICGC;COSMIC	19.028	Gain
STE_STE20_PAKA_PAK1_ST	Q15365	PCBP1	Q13153	PAK1	S43	E41K	41	Missense	proximal	-2	no	18.976	21.459	EPSD	TCGA;ICGC;COSMIC	19.028	Gain
STE_STE20_PAKA_PAK1_ST	Q15365	PCBP1	Q13153	PAK1	S43	R46L	46	Missense	distal	3	no	18.976	20.612	EPSD	TCGA;ICGC	19.028	Gain
STE_STE20_PAKA_PAK1_ST	Q15365	PCBP1	Q13153	PAK1	T60	C54S	54	Missense	distal	-6	no	20.436	22.130	PhosphoSitePlus;EPSD	TCGA;ICGC;COSMIC	19.028	Up-regulation
STE_STE20_PAKA_PAK1_ST	Q15365	PCBP1	Q13153	PAK1	S231	G226R	226	Missense	distal	-5	no	20.073	19.128	EPSD	TCGA;ICGC;COSMIC	19.028	Down-regulation
STE_STE20_PAKA_PAK1_ST	Q15365	PCBP1	Q13153	PAK1	S246	M250V	250	Missense	distal	4	no	19.378	19.276	EPSD	TCGA;ICGC;COSMIC	19.028	Down-regulation
STE_STE20_PAKA_PAK1_ST	P15056	BRAF	Q13153	PAK1	T167	A171E	171	Missense	distal	4	no	19.628	18.903	EPSD	TCGA;ICGC	19.028	Loss
STE_STE20_PAKA_PAK1_ST	P15056	BRAF	Q13153	PAK1	S323	A320T	320	Missense	distal	-3	no	20.800	21.166	EPSD	TCGA;ICGC;COSMIC	19.028	Up-regulation
STE_STE20_PAKA_PAK1_ST	P15056	BRAF	Q13153	PAK1	S323	P318L	318	Missense	distal	-5	no	20.800	20.699	EPSD	TCGA;ICGC;COSMIC	19.028	Down-regulation
STE_STE20_PAKA_PAK1_ST	P15056	BRAF	Q13153	PAK1	S323	P318S	318	Missense	distal	-5	no	20.800	19.938	EPSD	TCGA;ICGC;COSMIC	19.028	Down-regulation
STE_STE20_PAKA_PAK1_ST	P15056	BRAF	Q13153	PAK1	S323	S317F	317	Missense	distal	-6	no	20.800	20.033	EPSD	TCGA;ICGC;COSMIC	19.028	Down-regulation
STE_STE20_PAKA_PAK1_ST	P15056	BRAF	Q13153	PAK1	S363	S364L	364	Missense	proximal	1	no	19.461	19.631	EPSD	TCGA;ICGC;COSMIC	19.028	Up-regulation
STE_STE20_PAKA_PAK1_ST	P15056	BRAF	Q13153	PAK1	S363	P367R	367	Missense	distal	4	no	19.461	16.506	EPSD	TCGA;ICGC;COSMIC	19.028	Loss
STE_STE20_PAKA_PAK1_ST	P15056	BRAF	Q13153	PAK1	S363	P367S	367	Missense	distal	4	no	19.461	17.111	EPSD	TCGA;ICGC;COSMIC	19.028	Loss
STE_STE20_PAKA_PAK1_ST	P15056	BRAF	Q13153	PAK1	S364	S364L	364	Missense	central	0	yes	22.223	0.000	EPSD	TCGA;ICGC;COSMIC	19.028	Loss
STE_STE20_PAKA_PAK1_ST	P15056	BRAF	Q13153	PAK1	S364	P367R	367	Missense	distal	3	no	22.223	20.001	EPSD	TCGA;ICGC;COSMIC	19.028	Down-regulation
STE_STE20_PAKA_PAK1_ST	P15056	BRAF	Q13153	PAK1	S364	P367S	367	Missense	distal	3	no	22.223	19.843	EPSD	TCGA;ICGC;COSMIC	19.028	Down-regulation
STE_STE20_PAKA_PAK1_ST	P15056	BRAF	Q13153	PAK1	S365	S364L	364	Missense	proximal	-1	no	20.673	21.621	EPSD	TCGA;ICGC;COSMIC	19.028	Up-regulation
STE_STE20_PAKA_PAK1_ST	P15056	BRAF	Q13153	PAK1	S365	P367R	367	Missense	proximal	2	no	20.673	19.641	EPSD	TCGA;ICGC;COSMIC	19.028	Down-regulation
STE_STE20_PAKA_PAK1_ST	P15056	BRAF	Q13153	PAK1	S365	P367S	367	Missense	proximal	2	no	20.673	20.027	EPSD	TCGA;ICGC;COSMIC	19.028	Down-regulation
STE_STE20_PAKA_PAK1_ST	P15056	BRAF	Q13153	PAK1	S429	E433K	433	Missense	distal	4	no	21.489	21.637	EPSD	TCGA;ICGC;COSMIC	19.028	Up-regulation
STE_STE20_PAKA_PAK1_ST	P15056	BRAF	Q13153	PAK1	S430	E433K	433	Missense	distal	3	no	19.943	20.044	EPSD	TCGA;ICGC;COSMIC	19.028	Up-regulation
STE_STE20_PAKA_PAK1_ST	P15056	BRAF	Q13153	PAK1	T440	E433K	433	Missense	distal	-7	no	19.506	18.778	EPSD	TCGA;ICGC;COSMIC	19.028	Loss
STE_STE20_PAKA_PAK1_ST	P15056	BRAF	Q13153	PAK1	S446	E451G	451	Missense	distal	5	no	31.164	31.193	PhosphoSitePlus	TCGA;ICGC;COSMIC	19.028	Up-regulation
STE_STE20_PAKA_PAK1_ST	P15056	BRAF	Q13153	PAK1	S446	D449N	449	Missense	distal	3	no	31.164	31.441	PhosphoSitePlus	TCGA;ICGC;COSMIC	19.028	Up-regulation
STE_STE20_PAKA_PAK1_ST	P15056	BRAF	Q13153	PAK1	S447	E451G	451	Missense	distal	4	no	23.244	24.201	EPSD	TCGA;ICGC;COSMIC	19.028	Up-regulation
STE_STE20_PAKA_PAK1_ST	P15056	BRAF	Q13153	PAK1	S447	D449N	449	Missense	proximal	2	no	23.244	23.255	EPSD	TCGA;ICGC;COSMIC	19.028	Up-regulation
STE_STE20_PAKA_PAK1_ST	P15056	BRAF	Q13153	PAK1	S465	G469A	469	Missense	distal	4	no	21.053	20.820	EPSD	TCGA;ICGC;COSMIC;GDSC;CCLE	19.028	Down-regulation
STE_STE20_PAKA_PAK1_ST	P15056	BRAF	Q13153	PAK1	S465	G466V	466	Missense	proximal	1	no	21.053	21.055	EPSD	TCGA;ICGC;COSMIC;GDSC;CCLE	19.028	Up-regulation
STE_STE20_PAKA_PAK1_ST	P15056	BRAF	Q13153	PAK1	S465	G466E	466	Missense	proximal	1	no	21.053	21.307	EPSD	TCGA;ICGC;COSMIC	19.028	Up-regulation
STE_STE20_PAKA_PAK1_ST	P15056	BRAF	Q13153	PAK1	S465	G469V	469	Missense	distal	4	no	21.053	21.464	EPSD	TCGA;ICGC;COSMIC;GDSC;CCLE	19.028	Up-regulation
STE_STE20_PAKA_PAK1_ST	P15056	BRAF	Q13153	PAK1	S465	G466A	466	Missense	proximal	1	no	21.053	21.046	EPSD	TCGA;ICGC;COSMIC	19.028	Down-regulation
STE_STE20_PAKA_PAK1_ST	P15056	BRAF	Q13153	PAK1	S465	G464V	464	Missense	proximal	-1	no	21.053	22.120	EPSD	TCGA;ICGC;COSMIC;GDSC;CCLE	19.028	Up-regulation
STE_STE20_PAKA_PAK1_ST	P15056	BRAF	Q13153	PAK1	S465	G469R	469	Missense	distal	4	no	21.053	19.241	EPSD	TCGA;ICGC;COSMIC	19.028	Down-regulation
STE_STE20_PAKA_PAK1_ST	P15056	BRAF	Q13153	PAK1	S465	R462T	462	Missense	distal	-3	no	21.053	14.795	EPSD	TCGA;ICGC;COSMIC	19.028	Loss
STE_STE20_PAKA_PAK1_ST	P15056	BRAF	Q13153	PAK1	S465	F468C	468	Missense	distal	3	no	21.053	21.626	EPSD	TCGA;ICGC;COSMIC	19.028	Up-regulation
STE_STE20_PAKA_PAK1_ST	P15056	BRAF	Q13153	PAK1	S465	S467L	467	Missense	proximal	2	no	21.053	21.866	EPSD	TCGA;ICGC;COSMIC	19.028	Up-regulation
STE_STE20_PAKA_PAK1_ST	P15056	BRAF	Q13153	PAK1	S465	G469E	469	Missense	distal	4	no	21.053	20.095	EPSD	TCGA;ICGC;COSMIC	19.028	Down-regulation
STE_STE20_PAKA_PAK1_ST	P15056	BRAF	Q13153	PAK1	S465	V471I	471	Missense	distal	6	no	21.053	20.931	EPSD	TCGA;ICGC;COSMIC	19.028	Down-regulation
STE_STE20_PAKA_PAK1_ST	P15056	BRAF	Q13153	PAK1	S465	G464E	464	Missense	proximal	-1	no	21.053	22.106	EPSD	TCGA;ICGC;COSMIC;GDSC;CCLE	19.028	Up-regulation
STE_STE20_PAKA_PAK1_ST	Q96T58	SPEN	Q13153	PAK1	S43	P39S	39	Missense	distal	-4	no	28.417	28.469	EPSD	TCGA;ICGC;COSMIC	19.028	Up-regulation
STE_STE20_PAKA_PAK1_ST	Q96T58	SPEN	Q13153	PAK1	S96	S99Y	99	Missense	distal	3	no	15.531	19.310	EPSD	TCGA;ICGC;COSMIC	19.028	Gain
STE_STE20_PAKA_PAK1_ST	Q96T58	SPEN	Q13153	PAK1	S147	R142C	142	Missense	distal	-5	no	22.087	22.843	EPSD	TCGA;ICGC;COSMIC	19.028	Up-regulation
STE_STE20_PAKA_PAK1_ST	Q96T58	SPEN	Q13153	PAK1	T177	R176W	176	Missense	proximal	-1	no	20.661	17.041	EPSD	TCGA;ICGC;COSMIC	19.028	Loss
STE_STE20_PAKA_PAK1_ST	Q96T58	SPEN	Q13153	PAK1	T177	D172N	172	Missense	distal	-5	no	20.661	20.814	EPSD	TCGA;ICGC	19.028	Up-regulation
STE_STE20_PAKA_PAK1_ST	Q96T58	SPEN	Q13153	PAK1	S242	H246Y	246	Missense	distal	4	no	17.389	19.057	EPSD	TCGA;ICGC;COSMIC	19.028	Gain
STE_STE20_PAKA_PAK1_ST	Q96T58	SPEN	Q13153	PAK1	S244	S247L	247	Missense	distal	3	no	17.594	19.388	EPSD	TCGA;ICGC;COSMIC;CCLE	19.028	Gain
STE_STE20_PAKA_PAK1_ST	Q96T58	SPEN	Q13153	PAK1	S244	H246Y	246	Missense	proximal	2	no	17.594	19.912	EPSD	TCGA;ICGC;COSMIC	19.028	Gain
STE_STE20_PAKA_PAK1_ST	Q96T58	SPEN	Q13153	PAK1	S248	S247L	247	Missense	proximal	-1	no	18.390	19.338	EPSD	TCGA;ICGC;COSMIC;CCLE	19.028	Gain
STE_STE20_PAKA_PAK1_ST	Q96T58	SPEN	Q13153	PAK1	S248	H246Y	246	Missense	proximal	-2	no	18.390	19.464	EPSD	TCGA;ICGC;COSMIC	19.028	Gain
STE_STE20_PAKA_PAK1_ST	Q96T58	SPEN	Q13153	PAK1	S270	G271D	271	Missense	proximal	1	no	22.190	22.369	EPSD	TCGA;ICGC;COSMIC	19.028	Up-regulation
STE_STE20_PAKA_PAK1_ST	Q96T58	SPEN	Q13153	PAK1	S278	S278A	278	Missense	central	0	yes	20.454	0.000	EPSD	TCGA;ICGC;COSMIC	19.028	Loss
STE_STE20_PAKA_PAK1_ST	Q96T58	SPEN	Q13153	PAK1	S278	G271D	271	Missense	distal	-7	no	20.454	21.130	EPSD	TCGA;ICGC;COSMIC	19.028	Up-regulation
STE_STE20_PAKA_PAK1_ST	Q96T58	SPEN	Q13153	PAK1	S334	R332H	332	Missense	proximal	-2	no	27.419	22.005	EPSD	TCGA;ICGC;COSMIC	19.028	Down-regulation
STE_STE20_PAKA_PAK1_ST	Q96T58	SPEN	Q13153	PAK1	S334	S334R	334	Missense	central	0	yes	27.419	0.000	EPSD	TCGA;ICGC;COSMIC	19.028	Loss
STE_STE20_PAKA_PAK1_ST	Q96T58	SPEN	Q13153	PAK1	S623	Y626C	626	Missense	distal	3	no	30.999	28.374	EPSD	TCGA;ICGC;COSMIC	19.028	Down-regulation
STE_STE20_PAKA_PAK1_ST	Q96T58	SPEN	Q13153	PAK1	S623	Q628E	628	Missense	distal	5	no	30.999	31.003	EPSD	TCGA;ICGC;COSMIC	19.028	Up-regulation
STE_STE20_PAKA_PAK1_ST	Q96T58	SPEN	Q13153	PAK1	S623	R630C	630	Missense	distal	7	no	30.999	31.236	EPSD	TCGA;ICGC;COSMIC	19.028	Up-regulation
STE_STE20_PAKA_PAK1_ST	Q96T58	SPEN	Q13153	PAK1	S623	R630H	630	Missense	distal	7	no	30.999	31.046	EPSD	TCGA;ICGC;COSMIC	19.028	Up-regulation
STE_STE20_PAKA_PAK1_ST	Q96T58	SPEN	Q13153	PAK1	S725	I722T	722	Missense	distal	-3	no	11.644	20.853	EPSD	TCGA;ICGC;COSMIC	19.028	Gain
STE_STE20_PAKA_PAK1_ST	Q96T58	SPEN	Q13153	PAK1	S727	I722T	722	Missense	distal	-5	no	19.497	19.502	EPSD	TCGA;ICGC;COSMIC	19.028	Up-regulation
STE_STE20_PAKA_PAK1_ST	Q96T58	SPEN	Q13153	PAK1	S727	R733H	733	Missense	distal	6	no	19.497	19.941	EPSD	TCGA;ICGC	19.028	Up-regulation
STE_STE20_PAKA_PAK1_ST	Q96T58	SPEN	Q13153	PAK1	S727	R724Q	724	Missense	distal	-3	no	19.497	10.773	EPSD	TCGA;ICGC;COSMIC	19.028	Loss
STE_STE20_PAKA_PAK1_ST	Q96T58	SPEN	Q13153	PAK1	S736	R733H	733	Missense	distal	-3	no	25.750	19.679	EPSD	TCGA;ICGC	19.028	Down-regulation
STE_STE20_PAKA_PAK1_ST	Q96T58	SPEN	Q13153	PAK1	S736	G738A	738	Missense	proximal	2	no	25.750	25.506	EPSD	TCGA;ICGC;COSMIC	19.028	Down-regulation
STE_STE20_PAKA_PAK1_ST	Q96T58	SPEN	Q13153	PAK1	S847	E845K	845	Missense	proximal	-2	no	22.026	24.509	EPSD	TCGA;ICGC;COSMIC	19.028	Up-regulation
STE_STE20_PAKA_PAK1_ST	Q96T58	SPEN	Q13153	PAK1	S946	V952M	952	Missense	distal	6	no	20.456	20.701	EPSD	TCGA;ICGC;COSMIC	19.028	Up-regulation
STE_STE20_PAKA_PAK1_ST	Q96T58	SPEN	Q13153	PAK1	S946	L945R	945	Missense	proximal	-1	no	20.456	20.589	EPSD	TCGA;ICGC;COSMIC	19.028	Up-regulation
STE_STE20_PAKA_PAK1_ST	Q96T58	SPEN	Q13153	PAK1	S1268	E1271D	1271	Missense	distal	3	no	18.755	19.966	EPSD	TCGA;ICGC;COSMIC	19.028	Gain
STE_STE20_PAKA_PAK1_ST	Q96T58	SPEN	Q13153	PAK1	S1364	R1366Q	1366	Missense	proximal	2	no	23.112	23.449	EPSD	TCGA;ICGC;COSMIC	19.028	Up-regulation
STE_STE20_PAKA_PAK1_ST	Q96T58	SPEN	Q13153	PAK1	S1369	R1366Q	1366	Missense	distal	-3	no	22.353	13.629	EPSD	TCGA;ICGC;COSMIC	19.028	Loss
STE_STE20_PAKA_PAK1_ST	Q96T58	SPEN	Q13153	PAK1	S1392	S1390Y	1390	Missense	proximal	-2	no	15.810	19.623	EPSD	TCGA;ICGC;COSMIC	19.028	Gain
STE_STE20_PAKA_PAK1_ST	Q96T58	SPEN	Q13153	PAK1	S1396	L1398F	1398	Missense	proximal	2	no	23.744	23.014	EPSD	TCGA;ICGC;COSMIC	19.028	Down-regulation
STE_STE20_PAKA_PAK1_ST	Q96T58	SPEN	Q13153	PAK1	S1396	S1390Y	1390	Missense	distal	-6	no	23.744	22.857	EPSD	TCGA;ICGC;COSMIC	19.028	Down-regulation
STE_STE20_PAKA_PAK1_ST	Q96T58	SPEN	Q13153	PAK1	S1396	R1403Q	1403	Missense	distal	7	no	23.744	23.740	EPSD	TCGA;ICGC	19.028	Down-regulation
STE_STE20_PAKA_PAK1_ST	Q96T58	SPEN	Q13153	PAK1	S1402	L1398F	1398	Missense	distal	-4	no	20.231	20.359	EPSD	TCGA;ICGC;COSMIC	19.028	Up-regulation
STE_STE20_PAKA_PAK1_ST	Q96T58	SPEN	Q13153	PAK1	S1402	R1403Q	1403	Missense	proximal	1	no	20.231	19.895	EPSD	TCGA;ICGC	19.028	Down-regulation
STE_STE20_PAKA_PAK1_ST	Q96T58	SPEN	Q13153	PAK1	S1405	R1411I	1411	Missense	distal	6	no	18.952	19.431	EPSD	TCGA;ICGC;COSMIC	19.028	Gain
STE_STE20_PAKA_PAK1_ST	Q96T58	SPEN	Q13153	PAK1	S1424	N1429K	1429	Missense	distal	5	no	19.984	19.972	EPSD	TCGA;ICGC;COSMIC	19.028	Down-regulation
STE_STE20_PAKA_PAK1_ST	Q96T58	SPEN	Q13153	PAK1	S1424	E1427Q	1427	Missense	distal	3	no	19.984	20.410	EPSD	TCGA;ICGC;COSMIC	19.028	Up-regulation
STE_STE20_PAKA_PAK1_ST	Q96T58	SPEN	Q13153	PAK1	S1424	K1430T	1430	Missense	distal	6	no	19.984	19.498	EPSD	TCGA;ICGC;COSMIC	19.028	Down-regulation
STE_STE20_PAKA_PAK1_ST	Q96T58	SPEN	Q13153	PAK1	S1433	N1429K	1429	Missense	distal	-4	no	21.348	22.058	EPSD	TCGA;ICGC;COSMIC	19.028	Up-regulation
STE_STE20_PAKA_PAK1_ST	Q96T58	SPEN	Q13153	PAK1	S1433	D1437H	1437	Missense	distal	4	no	21.348	20.858	EPSD	TCGA;ICGC;COSMIC	19.028	Down-regulation
STE_STE20_PAKA_PAK1_ST	Q96T58	SPEN	Q13153	PAK1	S1433	E1427Q	1427	Missense	distal	-6	no	21.348	20.988	EPSD	TCGA;ICGC;COSMIC	19.028	Down-regulation
STE_STE20_PAKA_PAK1_ST	Q96T58	SPEN	Q13153	PAK1	S1433	K1430T	1430	Missense	distal	-3	no	21.348	16.277	EPSD	TCGA;ICGC;COSMIC	19.028	Loss
STE_STE20_PAKA_PAK1_ST	Q96T58	SPEN	Q13153	PAK1	S1433	F1434S	1434	Missense	proximal	1	no	21.348	21.087	EPSD	TCGA;ICGC;COSMIC	19.028	Down-regulation
STE_STE20_PAKA_PAK1_ST	Q96T58	SPEN	Q13153	PAK1	T1441	D1437H	1437	Missense	distal	-4	no	19.825	19.798	EPSD	TCGA;ICGC;COSMIC	19.028	Down-regulation
STE_STE20_PAKA_PAK1_ST	Q96T58	SPEN	Q13153	PAK1	T1441	F1434S	1434	Missense	distal	-7	no	19.825	20.822	EPSD	TCGA;ICGC;COSMIC	19.028	Up-regulation
STE_STE20_PAKA_PAK1_ST	Q96T58	SPEN	Q13153	PAK1	S1453	R1458C	1458	Missense	distal	5	no	19.527	19.550	EPSD	TCGA;ICGC;COSMIC	19.028	Up-regulation
STE_STE20_PAKA_PAK1_ST	Q96T58	SPEN	Q13153	PAK1	S1453	S1457A	1457	Missense	distal	4	no	19.527	20.502	EPSD	TCGA;ICGC;COSMIC	19.028	Up-regulation
STE_STE20_PAKA_PAK1_ST	Q96T58	SPEN	Q13153	PAK1	S1453	A1451T	1451	Missense	proximal	-2	no	19.527	22.483	EPSD	TCGA;ICGC;COSMIC	19.028	Up-regulation
STE_STE20_PAKA_PAK1_ST	Q96T58	SPEN	Q13153	PAK1	S1455	R1458C	1458	Missense	distal	3	no	19.989	20.985	EPSD	TCGA;ICGC;COSMIC	19.028	Up-regulation
STE_STE20_PAKA_PAK1_ST	Q96T58	SPEN	Q13153	PAK1	S1455	S1457A	1457	Missense	proximal	2	no	19.989	20.893	EPSD	TCGA;ICGC;COSMIC	19.028	Up-regulation
STE_STE20_PAKA_PAK1_ST	Q96T58	SPEN	Q13153	PAK1	S1455	A1451T	1451	Missense	distal	-4	no	19.989	20.405	EPSD	TCGA;ICGC;COSMIC	19.028	Up-regulation
STE_STE20_PAKA_PAK1_ST	Q96T58	SPEN	Q13153	PAK1	S1485	D1484E	1484	Missense	proximal	-1	no	23.714	22.410	EPSD	TCGA;ICGC;COSMIC	19.028	Down-regulation
STE_STE20_PAKA_PAK1_ST	Q96T58	SPEN	Q13153	PAK1	S1485	P1489R	1489	Missense	distal	4	no	23.714	20.760	EPSD	TCGA;ICGC;COSMIC	19.028	Down-regulation
STE_STE20_PAKA_PAK1_ST	Q96T58	SPEN	Q13153	PAK1	S1485	R1488I	1488	Missense	distal	3	no	23.714	25.094	EPSD	TCGA;ICGC;COSMIC;GDSC;CCLE	19.028	Up-regulation
STE_STE20_PAKA_PAK1_ST	Q96T58	SPEN	Q13153	PAK1	S1504	D1509N	1509	Missense	distal	5	no	24.271	24.283	EPSD	TCGA;ICGC;COSMIC	19.028	Up-regulation
STE_STE20_PAKA_PAK1_ST	Q96T58	SPEN	Q13153	PAK1	S1504	D1510N	1510	Missense	distal	6	no	24.271	24.416	EPSD	TCGA;ICGC;COSMIC	19.028	Up-regulation
STE_STE20_PAKA_PAK1_ST	Q96T58	SPEN	Q13153	PAK1	S1504	K1497N	1497	Missense	distal	-7	no	24.271	23.655	EPSD	TCGA;ICGC	19.028	Down-regulation
STE_STE20_PAKA_PAK1_ST	Q96T58	SPEN	Q13153	PAK1	S1557	S1557F	1557	Missense	central	0	yes	21.149	0.000	EPSD	TCGA;ICGC;COSMIC	19.028	Loss
STE_STE20_PAKA_PAK1_ST	Q96T58	SPEN	Q13153	PAK1	S1557	E1550D	1550	Missense	distal	-7	no	21.149	20.210	EPSD	TCGA;ICGC;COSMIC	19.028	Down-regulation
STE_STE20_PAKA_PAK1_ST	Q96T58	SPEN	Q13153	PAK1	S1575	E1578Q	1578	Missense	distal	3	no	21.755	22.181	EPSD	TCGA;ICGC;COSMIC	19.028	Up-regulation
STE_STE20_PAKA_PAK1_ST	Q96T58	SPEN	Q13153	PAK1	S1575	S1571N	1571	Missense	distal	-4	no	21.755	21.304	EPSD	TCGA;ICGC;COSMIC	19.028	Down-regulation
STE_STE20_PAKA_PAK1_ST	Q96T58	SPEN	Q13153	PAK1	S1575	D1574N	1574	Missense	proximal	-1	no	21.755	19.578	EPSD	TCGA;ICGC;COSMIC	19.028	Down-regulation
STE_STE20_PAKA_PAK1_ST	Q96T58	SPEN	Q13153	PAK1	S1575	L1582P	1582	Missense	distal	7	no	21.755	21.774	EPSD	TCGA;ICGC	19.028	Up-regulation
STE_STE20_PAKA_PAK1_ST	Q96T58	SPEN	Q13153	PAK1	S1585	L1582P	1582	Missense	distal	-3	no	18.255	19.063	EPSD	TCGA;ICGC	19.028	Gain
STE_STE20_PAKA_PAK1_ST	Q96T58	SPEN	Q13153	PAK1	T1643	S1641R	1641	Missense	proximal	-2	no	12.773	20.926	EPSD	TCGA;ICGC;COSMIC	19.028	Gain
STE_STE20_PAKA_PAK1_ST	Q96T58	SPEN	Q13153	PAK1	S1797	E1792K	1792	Missense	distal	-5	no	19.532	19.592	EPSD	TCGA;ICGC;COSMIC	19.028	Up-regulation
STE_STE20_PAKA_PAK1_ST	Q96T58	SPEN	Q13153	PAK1	S1897	R1902W	1902	Missense	distal	5	no	19.043	19.074	EPSD	TCGA;ICGC;COSMIC	19.028	Up-regulation
STE_STE20_PAKA_PAK1_ST	Q96T58	SPEN	Q13153	PAK1	S1897	E1891A	1891	Missense	distal	-6	no	19.043	18.992	EPSD	TCGA;ICGC;COSMIC	19.028	Loss
STE_STE20_PAKA_PAK1_ST	Q96T58	SPEN	Q13153	PAK1	S2354	E2353D	2353	Missense	proximal	-1	no	18.245	19.550	EPSD	TCGA;ICGC;COSMIC	19.028	Gain
STE_STE20_PAKA_PAK1_ST	Q96T58	SPEN	Q13153	PAK1	S2392	S2387N	2387	Missense	distal	-5	no	28.081	28.717	EPSD	TCGA;ICGC;COSMIC	19.028	Up-regulation
STE_STE20_PAKA_PAK1_ST	Q96T58	SPEN	Q13153	PAK1	S2392	Q2386H	2386	Missense	distal	-6	no	28.081	28.484	EPSD	TCGA;ICGC;COSMIC	19.028	Up-regulation
STE_STE20_PAKA_PAK1_ST	Q96T58	SPEN	Q13153	PAK1	S2397	S2400Y	2400	Missense	distal	3	no	19.084	22.863	EPSD	TCGA;ICGC;COSMIC	19.028	Up-regulation
STE_STE20_PAKA_PAK1_ST	Q96T58	SPEN	Q13153	PAK1	S2397	D2401N	2401	Missense	distal	4	no	19.084	18.705	EPSD	TCGA;ICGC;COSMIC	19.028	Loss
STE_STE20_PAKA_PAK1_ST	Q96T58	SPEN	Q13153	PAK1	S2397	S2403R	2403	Missense	distal	6	no	19.084	18.819	EPSD	TCGA;ICGC;COSMIC	19.028	Loss
STE_STE20_PAKA_PAK1_ST	Q96T58	SPEN	Q13153	PAK1	S2407	S2400Y	2400	Missense	distal	-7	no	19.744	18.234	EPSD	TCGA;ICGC;COSMIC	19.028	Loss
STE_STE20_PAKA_PAK1_ST	Q96T58	SPEN	Q13153	PAK1	S2407	D2401N	2401	Missense	distal	-6	no	19.744	19.906	EPSD	TCGA;ICGC;COSMIC	19.028	Up-regulation
STE_STE20_PAKA_PAK1_ST	Q96T58	SPEN	Q13153	PAK1	S2407	S2411L	2411	Missense	distal	4	no	19.744	20.536	EPSD	TCGA;ICGC;COSMIC	19.028	Up-regulation
STE_STE20_PAKA_PAK1_ST	Q96T58	SPEN	Q13153	PAK1	S2407	S2403R	2403	Missense	distal	-4	no	19.744	20.210	EPSD	TCGA;ICGC;COSMIC	19.028	Up-regulation
STE_STE20_PAKA_PAK1_ST	Q96T58	SPEN	Q13153	PAK1	T2423	S2426Y	2426	Missense	distal	3	no	15.511	19.290	EPSD	TCGA;ICGC;COSMIC	19.028	Gain
STE_STE20_PAKA_PAK1_ST	Q96T58	SPEN	Q13153	PAK1	S2481	S2481L	2481	Missense	central	0	yes	20.164	0.000	EPSD	TCGA;ICGC;COSMIC	19.028	Loss
STE_STE20_PAKA_PAK1_ST	Q96T58	SPEN	Q13153	PAK1	S2481	G2488V	2488	Missense	distal	7	no	20.164	20.115	EPSD	TCGA;ICGC;COSMIC	19.028	Down-regulation
STE_STE20_PAKA_PAK1_ST	Q96T58	SPEN	Q13153	PAK1	S2512	P2516L	2516	Missense	distal	4	no	21.026	19.468	EPSD	TCGA;ICGC;COSMIC	19.028	Down-regulation
STE_STE20_PAKA_PAK1_ST	Q96T58	SPEN	Q13153	PAK1	S2512	P2519L	2519	Missense	distal	7	no	21.026	21.007	EPSD	TCGA;ICGC;COSMIC	19.028	Down-regulation
STE_STE20_PAKA_PAK1_ST	Q96T58	SPEN	Q13153	PAK1	S3014	I3007L	3007	Missense	distal	-7	no	22.994	23.118	EPSD	TCGA;ICGC;COSMIC	19.028	Up-regulation
STE_STE20_PAKA_PAK1_ST	Q96T58	SPEN	Q13153	PAK1	S3014	A3009G	3009	Missense	distal	-5	no	22.994	23.282	EPSD	TCGA	19.028	Up-regulation
STE_STE20_PAKA_PAK1_ST	Q96T58	SPEN	Q13153	PAK1	S3014	P3008S	3008	Missense	distal	-6	no	22.994	23.051	EPSD	TCGA;ICGC;COSMIC	19.028	Up-regulation
STE_STE20_PAKA_PAK1_ST	Q96T58	SPEN	Q13153	PAK1	S3014	V3013D	3013	Missense	proximal	-1	no	22.994	24.284	EPSD	TCGA;ICGC;COSMIC	19.028	Up-regulation
STE_STE20_PAKA_PAK1_ST	Q96T58	SPEN	Q13153	PAK1	S3014	R3011Q	3011	Missense	distal	-3	no	22.994	14.269	EPSD	TCGA;ICGC;COSMIC;GDSC	19.028	Loss
STE_STE20_PAKA_PAK1_ST	Q96T58	SPEN	Q13153	PAK1	S3014	L3016V	3016	Missense	proximal	2	no	22.994	23.154	EPSD	TCGA;ICGC;COSMIC	19.028	Up-regulation
STE_STE20_PAKA_PAK1_ST	Q96T58	SPEN	Q13153	PAK1	T3139	P3140L	3140	Missense	proximal	1	no	20.528	20.815	EPSD	TCGA;ICGC;COSMIC	19.028	Up-regulation
STE_STE20_PAKA_PAK1_ST	Q96T58	SPEN	Q13153	PAK1	T3139	R3132K	3132	Missense	distal	-7	no	20.528	19.909	EPSD	TCGA;ICGC;COSMIC	19.028	Down-regulation
STE_STE20_PAKA_PAK1_ST	Q96T58	SPEN	Q13153	PAK1	S3430	S3433F	3433	Missense	distal	3	no	21.419	22.000	EPSD	TCGA;ICGC;COSMIC	19.028	Up-regulation
STE_STE20_PAKA_PAK1_ST	Q96T58	SPEN	Q13153	PAK1	S3436	S3433F	3433	Missense	distal	-3	no	16.577	20.089	EPSD	TCGA;ICGC;COSMIC	19.028	Gain
STE_STE20_PAKA_PAK1_ST	Q96T58	SPEN	Q13153	PAK1	S3486	S3492Y	3492	Missense	distal	6	no	21.864	22.508	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	19.028	Up-regulation
STE_STE20_PAKA_PAK1_ST	O14965	AURKA	Q13153	PAK1	S53	R56H	56	Missense	distal	3	no	18.999	19.253	EPSD	TCGA;ICGC;COSMIC	19.028	Gain
STE_STE20_PAKA_PAK1_ST	O14965	AURKA	Q13153	PAK1	S53	R56C	56	Missense	distal	3	no	18.999	19.995	EPSD	TCGA;ICGC;COSMIC	19.028	Gain
STE_STE20_PAKA_PAK1_ST	O14965	AURKA	Q13153	PAK1	S53	N52H	52	Missense	proximal	-1	no	18.999	20.078	EPSD	TCGA;ICGC;COSMIC	19.028	Gain
STE_STE20_PAKA_PAK1_ST	O14965	AURKA	Q13153	PAK1	S67	H68Q	68	Missense	proximal	1	no	19.585	19.511	EPSD	TCGA	19.028	Down-regulation
STE_STE20_PAKA_PAK1_ST	O14965	AURKA	Q13153	PAK1	T287	A281T	281	Missense	distal	-6	no	19.536	19.463	EPSD	TCGA;ICGC;COSMIC	19.028	Down-regulation
STE_STE20_PAKA_PAK1_ST	O14965	AURKA	Q13153	PAK1	T288	A281T	281	Missense	distal	-7	no	27.239	27.382	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	19.028	Up-regulation
STE_STE20_PAKA_PAK1_ST	O14965	AURKA	Q13153	PAK1	S342	E336D	336	Missense	distal	-6	no	30.054	29.157	PhosphoSitePlus;EPSD	TCGA;ICGC;COSMIC	19.028	Down-regulation
STE_STE20_PAKA_PAK1_ST	O14965	AURKA	Q13153	PAK1	S342	R343Q	343	Missense	proximal	1	no	30.054	29.719	PhosphoSitePlus;EPSD	TCGA;ICGC;COSMIC;GDSC	19.028	Down-regulation
STE_STE20_PAKA_PAK1_ST	P16949	STMN1	Q13153	PAK1	S25	S28P	28	Missense	distal	3	no	18.139	20.520	EPSD	TCGA;ICGC	19.028	Gain
STE_STE20_PAKA_PAK1_ST	P16949	STMN1	Q13153	PAK1	S25	K29I	29	Missense	distal	4	no	18.139	19.258	EPSD	TCGA;ICGC;COSMIC	19.028	Gain
STE_STE20_PAKA_PAK1_ST	P16949	STMN1	Q13153	PAK1	S28	S31Y	31	Missense	distal	3	no	17.392	21.171	EPSD	TCGA;COSMIC	19.028	Gain
STE_STE20_PAKA_PAK1_ST	P16949	STMN1	Q13153	PAK1	S31	S28P	28	Missense	distal	-3	no	16.469	19.457	EPSD	TCGA;ICGC	19.028	Gain
STE_STE20_PAKA_PAK1_ST	P16949	STMN1	Q13153	PAK1	S38	S31Y	31	Missense	distal	-7	no	19.215	17.705	PhosphoSitePlus;EPSD	TCGA;COSMIC	19.028	Loss
STE_STE20_PAKA_PAK1_ST	P16949	STMN1	Q13153	PAK1	S38	P39S	39	Missense	proximal	1	no	19.215	19.332	PhosphoSitePlus;EPSD	TCGA;ICGC;COSMIC	19.028	Up-regulation
STE_STE20_PAKA_PAK1_ST	P16949	STMN1	Q13153	PAK1	S46	P39S	39	Missense	distal	-7	no	22.410	22.667	EPSD	TCGA;ICGC;COSMIC	19.028	Up-regulation
STE_STE20_PAKA_PAK1_ST	P16949	STMN1	Q13153	PAK1	S46	L47R	47	Missense	proximal	1	no	22.410	22.642	EPSD	TCGA;ICGC;COSMIC	19.028	Up-regulation
STE_STE20_PAKA_PAK1_ST	P16949	STMN1	Q13153	PAK1	S63	E58D	58	Missense	distal	-5	no	30.985	31.411	EPSD	TCGA;ICGC;COSMIC	19.028	Up-regulation
STE_STE20_PAKA_PAK1_ST	P16949	STMN1	Q13153	PAK1	S63	A66G	66	Missense	distal	3	no	30.985	32.016	EPSD	TCGA;ICGC;COSMIC	19.028	Up-regulation
STE_STE20_PAKA_PAK1_ST	P16949	STMN1	Q13153	PAK1	S63	R61H	61	Missense	proximal	-2	no	30.985	25.571	EPSD	TCGA;ICGC;COSMIC	19.028	Down-regulation
STE_STE20_PAKA_PAK1_ST	P16949	STMN1	Q13153	PAK1	S63	S63P	63	Missense	central	0	yes	30.985	0.000	EPSD	TCGA;ICGC;COSMIC	19.028	Loss
STE_STE20_PAKA_PAK1_ST	P35240	NF2	Q13153	PAK1	S255	R249K	249	Missense	distal	-6	no	21.639	19.582	EPSD	TCGA;ICGC;COSMIC	19.028	Down-regulation
STE_STE20_PAKA_PAK1_ST	P35240	NF2	Q13153	PAK1	S265	F271L	271	Missense	distal	6	no	19.418	19.314	EPSD	TCGA;ICGC	19.028	Down-regulation
STE_STE20_PAKA_PAK1_ST	P35240	NF2	Q13153	PAK1	S315	A313S	313	Missense	proximal	-2	no	19.055	18.722	EPSD	TCGA;ICGC;COSMIC	19.028	Loss
STE_STE20_PAKA_PAK1_ST	Q9UQ80	PA2G4	Q13153	PAK1	S252	P251L	251	Missense	proximal	-1	no	18.045	22.237	EPSD	TCGA;ICGC;COSMIC	19.028	Gain
STE_STE20_PAKA_PAK1_ST	Q9UQ80	PA2G4	Q13153	PAK1	T334	P337R	337	Missense	distal	3	no	22.274	20.052	EPSD	TCGA;ICGC;COSMIC	19.028	Down-regulation
STE_STE20_PAKA_PAK1_ST	Q9UQ80	PA2G4	Q13153	PAK1	T334	N328S	328	Missense	distal	-6	no	22.274	21.901	EPSD	TCGA;ICGC;COSMIC	19.028	Down-regulation
STE_STE20_PAKA_PAK1_ST	Q9UQ80	PA2G4	Q13153	PAK1	T334	P327H	327	Missense	distal	-7	no	22.274	21.750	EPSD	TCGA;ICGC;COSMIC	19.028	Down-regulation
STE_STE20_PAKA_PAK1_ST	Q9UQ80	PA2G4	Q13153	PAK1	S335	P337R	337	Missense	proximal	2	no	20.462	19.430	EPSD	TCGA;ICGC;COSMIC	19.028	Down-regulation
STE_STE20_PAKA_PAK1_ST	Q9UQ80	PA2G4	Q13153	PAK1	S335	N328S	328	Missense	distal	-7	no	20.462	21.128	EPSD	TCGA;ICGC;COSMIC	19.028	Up-regulation
STE_STE20_PAKA_PAK1_ST	Q9UQ80	PA2G4	Q13153	PAK1	S375	E379D	379	Missense	distal	4	no	18.905	19.405	EPSD	TCGA;ICGC;COSMIC	19.028	Gain
STE_STE20_PAKA_PAK1_ST	P53667	LIMK1	Q13153	PAK1	S281	P280S	280	Missense	proximal	-1	no	16.480	19.724	EPSD	TCGA;COSMIC	19.028	Gain
STE_STE20_PAKA_PAK1_ST	P53667	LIMK1	Q13153	PAK1	S298	P303T	303	Missense	distal	5	no	19.466	19.439	EPSD	TCGA;COSMIC	19.028	Down-regulation
STE_STE20_PAKA_PAK1_ST	P53667	LIMK1	Q13153	PAK1	S323	R329Q	329	Missense	distal	6	no	19.027	19.179	EPSD	TCGA;COSMIC	19.028	Gain
STE_STE20_PAKA_PAK1_ST	P53667	LIMK1	Q13153	PAK1	S323	R329W	329	Missense	distal	6	no	19.027	19.919	EPSD	TCGA;COSMIC	19.028	Gain
STE_STE20_PAKA_PAK1_ST	P53667	LIMK1	Q13153	PAK1	S323	R325H	325	Missense	proximal	2	no	19.027	19.347	EPSD	TCGA	19.028	Gain
STE_STE20_PAKA_PAK1_ST	P53667	LIMK1	Q13153	PAK1	S497	L495M	495	Missense	proximal	-2	no	15.493	19.819	EPSD	TCGA;COSMIC	19.028	Gain
STE_STE20_PAKA_PAK1_ST	P53667	LIMK1	Q13153	PAK1	T508	D502G	502	Missense	distal	-6	no	23.947	23.450	PhosphoSitePlus	TCGA;COSMIC	19.028	Down-regulation
STE_STE20_PAKA_PAK1_ST	P53667	LIMK1	Q13153	PAK1	T508	P513L	513	Missense	distal	5	no	23.947	23.933	PhosphoSitePlus	TCGA;COSMIC	19.028	Down-regulation
STE_STE20_PAKA_PAK1_ST	P53667	LIMK1	Q13153	PAK1	S534	L539M	539	Missense	distal	5	no	20.848	20.865	EPSD	TCGA;COSMIC	19.028	Up-regulation
STE_STE20_PAKA_PAK1_ST	Q70Z35	PREX2	Q13153	PAK1	S901	S907C	907	Missense	distal	6	no	19.357	19.728	EPSD	TCGA;ICGC;COSMIC	19.028	Up-regulation
STE_STE20_PAKA_PAK1_ST	Q70Z35	PREX2	Q13153	PAK1	S901	R908G	908	Missense	distal	7	no	19.357	19.524	EPSD	TCGA;ICGC;COSMIC	19.028	Up-regulation
STE_STE20_PAKA_PAK1_ST	Q70Z35	PREX2	Q13153	PAK1	S901	S901P	901	Missense	central	0	yes	19.357	0.000	EPSD	TCGA	19.028	Loss
STE_STE20_PAKA_PAK1_ST	Q70Z35	PREX2	Q13153	PAK1	S901	R899I	899	Missense	proximal	-2	no	19.357	13.073	EPSD	TCGA;ICGC;COSMIC	19.028	Loss
STE_STE20_PAKA_PAK1_ST	Q70Z35	PREX2	Q13153	PAK1	S901	S901F	901	Missense	central	0	yes	19.357	0.000	EPSD	TCGA;ICGC;COSMIC	19.028	Loss
STE_STE20_PAKA_PAK1_ST	Q70Z35	PREX2	Q13153	PAK1	S901	R908C	908	Missense	distal	7	no	19.357	19.595	EPSD	TCGA;ICGC;COSMIC	19.028	Up-regulation
STE_STE20_PAKA_PAK1_ST	Q70Z35	PREX2	Q13153	PAK1	S901	K905T	905	Missense	distal	4	no	19.357	18.592	EPSD	TCGA;ICGC;COSMIC	19.028	Loss
STE_STE20_PAKA_PAK1_ST	Q70Z35	PREX2	Q13153	PAK1	S901	I900M	900	Missense	proximal	-1	no	19.357	17.892	EPSD	TCGA;ICGC;COSMIC	19.028	Loss
STE_STE20_PAKA_PAK1_ST	Q70Z35	PREX2	Q13153	PAK1	S907	S907C	907	Missense	central	0	yes	23.618	0.000	EPSD	TCGA;ICGC;COSMIC	19.028	Loss
STE_STE20_PAKA_PAK1_ST	Q70Z35	PREX2	Q13153	PAK1	S907	R908G	908	Missense	proximal	1	no	23.618	23.137	EPSD	TCGA;ICGC;COSMIC	19.028	Down-regulation
STE_STE20_PAKA_PAK1_ST	Q70Z35	PREX2	Q13153	PAK1	S907	S901P	901	Missense	distal	-6	no	23.618	23.560	EPSD	TCGA	19.028	Down-regulation
STE_STE20_PAKA_PAK1_ST	Q70Z35	PREX2	Q13153	PAK1	S907	A914V	914	Missense	distal	7	no	23.618	23.622	EPSD	TCGA;ICGC;COSMIC	19.028	Up-regulation
STE_STE20_PAKA_PAK1_ST	Q70Z35	PREX2	Q13153	PAK1	S907	S901F	901	Missense	distal	-6	no	23.618	22.851	EPSD	TCGA;ICGC;COSMIC	19.028	Down-regulation
STE_STE20_PAKA_PAK1_ST	Q70Z35	PREX2	Q13153	PAK1	S907	R908C	908	Missense	proximal	1	no	23.618	23.174	EPSD	TCGA;ICGC;COSMIC	19.028	Down-regulation
STE_STE20_PAKA_PAK1_ST	Q70Z35	PREX2	Q13153	PAK1	S907	K905T	905	Missense	proximal	-2	no	23.618	22.793	EPSD	TCGA;ICGC;COSMIC	19.028	Down-regulation
STE_STE20_PAKA_PAK1_ST	Q70Z35	PREX2	Q13153	PAK1	S907	I900M	900	Missense	distal	-7	no	23.618	22.813	EPSD	TCGA;ICGC;COSMIC	19.028	Down-regulation
STE_STE20_PAKA_PAK1_ST	Q70Z35	PREX2	Q13153	PAK1	T952	V945G	945	Missense	distal	-7	no	19.141	19.809	EPSD	TCGA	19.028	Up-regulation
STE_STE20_PAKA_PAK1_ST	Q70Z35	PREX2	Q13153	PAK1	T952	T950I	950	Missense	proximal	-2	no	19.141	17.720	EPSD	TCGA;ICGC;COSMIC	19.028	Loss
STE_STE20_PAKA_PAK1_ST	Q70Z35	PREX2	Q13153	PAK1	T952	G955R	955	Missense	distal	3	no	19.141	16.555	EPSD	TCGA;ICGC;COSMIC	19.028	Loss
STE_STE20_PAKA_PAK1_ST	Q70Z35	PREX2	Q13153	PAK1	T1064	E1061K	1061	Missense	distal	-3	no	11.008	24.800	EPSD	TCGA;ICGC;COSMIC	19.028	Gain
STE_STE20_PAKA_PAK1_ST	Q70Z35	PREX2	Q13153	PAK1	S1065	R1062C	1062	Missense	distal	-3	no	31.089	11.133	EPSD	TCGA;ICGC;COSMIC	19.028	Loss
STE_STE20_PAKA_PAK1_ST	Q70Z35	PREX2	Q13153	PAK1	S1065	E1061K	1061	Missense	distal	-4	no	31.089	31.168	EPSD	TCGA;ICGC;COSMIC	19.028	Up-regulation
STE_STE20_PAKA_PAK1_ST	Q70Z35	PREX2	Q13153	PAK1	S1065	P1070L	1070	Missense	distal	5	no	31.089	31.074	EPSD	TCGA;ICGC;COSMIC	19.028	Down-regulation
STE_STE20_PAKA_PAK1_ST	Q70Z35	PREX2	Q13153	PAK1	S1065	L1060V	1060	Missense	distal	-5	no	31.089	30.831	EPSD	TCGA;ICGC	19.028	Down-regulation
STE_STE20_PAKA_PAK1_ST	Q70Z35	PREX2	Q13153	PAK1	S1107	N1112K	1112	Missense	distal	5	no	22.274	22.262	PhosphoSitePlus	TCGA;ICGC;COSMIC	19.028	Down-regulation
STE_STE20_PAKA_PAK1_ST	Q70Z35	PREX2	Q13153	PAK1	S1107	D1110Y	1110	Missense	distal	3	no	22.274	24.610	PhosphoSitePlus	TCGA;ICGC;COSMIC	19.028	Up-regulation
STE_STE20_PAKA_PAK1_ST	Q70Z35	PREX2	Q13153	PAK1	T1501	C1498R	1498	Missense	distal	-3	no	0.184	20.140	EPSD	TCGA;ICGC;COSMIC;CCLE	19.028	Gain
STE_STE20_PAKA_PAK1_ST	Q02750	MAP2K1	Q13153	PAK1	T55	R49H	49	Missense	distal	-6	no	19.774	18.916	EPSD	TCGA;ICGC;COSMIC	19.028	Loss
STE_STE20_PAKA_PAK1_ST	Q02750	MAP2K1	Q13153	PAK1	T55	Q56P	56	Missense	proximal	1	no	19.774	19.591	EPSD	TCGA;ICGC;COSMIC;GDSC;CCLE	19.028	Down-regulation
STE_STE20_PAKA_PAK1_ST	Q02750	MAP2K1	Q13153	PAK1	T55	K57N	57	Missense	proximal	2	no	19.774	19.792	EPSD	TCGA;ICGC;COSMIC;CCLE	19.028	Up-regulation
STE_STE20_PAKA_PAK1_ST	Q02750	MAP2K1	Q13153	PAK1	T55	K57T	57	Missense	proximal	2	no	19.774	18.705	EPSD	TCGA;ICGC;COSMIC	19.028	Loss
STE_STE20_PAKA_PAK1_ST	Q02750	MAP2K1	Q13153	PAK1	T55	F53L	53	Missense	proximal	-2	no	19.774	16.828	EPSD	TCGA;ICGC;COSMIC;GDSC;CCLE	19.028	Loss
STE_STE20_PAKA_PAK1_ST	Q02750	MAP2K1	Q13153	PAK1	T55	F53V	53	Missense	proximal	-2	no	19.774	19.833	EPSD	TCGA;ICGC;COSMIC	19.028	Up-regulation
STE_STE20_PAKA_PAK1_ST	Q02750	MAP2K1	Q13153	PAK1	T55	F53I	53	Missense	proximal	-2	no	19.774	19.108	EPSD	TCGA;ICGC;COSMIC	19.028	Down-regulation
STE_STE20_PAKA_PAK1_ST	Q02750	MAP2K1	Q13153	PAK1	T292	G294R	294	Missense	proximal	2	no	27.677	26.143	EPSD	TCGA;ICGC;COSMIC	19.028	Down-regulation
STE_STE20_PAKA_PAK1_ST	Q02750	MAP2K1	Q13153	PAK1	T292	G294V	294	Missense	proximal	2	no	27.677	27.503	EPSD	TCGA;ICGC;COSMIC	19.028	Down-regulation
STE_STE20_PAKA_PAK1_ST	Q02750	MAP2K1	Q13153	PAK1	T292	G294E	294	Missense	proximal	2	no	27.677	26.557	EPSD	TCGA;ICGC;COSMIC	19.028	Down-regulation
STE_STE20_PAKA_PAK1_ST	Q02750	MAP2K1	Q13153	PAK1	T292	P290S	290	Missense	proximal	-2	no	27.677	23.050	EPSD	TCGA;ICGC	19.028	Down-regulation
STE_STE20_PAKA_PAK1_ST	Q02750	MAP2K1	Q13153	PAK1	S298	G294R	294	Missense	distal	-4	no	33.212	34.099	PhosphoSitePlus	TCGA;ICGC;COSMIC	19.028	Up-regulation
STE_STE20_PAKA_PAK1_ST	Q02750	MAP2K1	Q13153	PAK1	S298	G294V	294	Missense	distal	-4	no	33.212	33.540	PhosphoSitePlus	TCGA;ICGC;COSMIC	19.028	Up-regulation
STE_STE20_PAKA_PAK1_ST	Q02750	MAP2K1	Q13153	PAK1	S298	G294E	294	Missense	distal	-4	no	33.212	33.813	PhosphoSitePlus	TCGA;ICGC;COSMIC	19.028	Up-regulation
STE_STE20_PAKA_PAK1_ST	Q02750	MAP2K1	Q13153	PAK1	S298	R305Q	305	Missense	distal	7	no	33.212	33.207	PhosphoSitePlus	TCGA;ICGC	19.028	Down-regulation
STE_STE20_PAKA_PAK1_ST	Q02750	MAP2K1	Q13153	PAK1	S298	D303N	303	Missense	distal	5	no	33.212	33.224	PhosphoSitePlus	TCGA;ICGC;COSMIC	19.028	Up-regulation
STE_STE20_PAKA_PAK1_ST	Q02750	MAP2K1	Q13153	PAK1	S299	R305Q	305	Missense	distal	6	no	18.971	19.123	EPSD	TCGA;ICGC	19.028	Gain
STE_STE20_PAKA_PAK1_ST	Q13363	CTBP1	Q13153	PAK1	S100	D106N	106	Missense	distal	6	no	19.378	19.523	EPSD	TCGA;GDSC;CCLE	19.028	Up-regulation
STE_STE20_PAKA_PAK1_ST	Q13363	CTBP1	Q13153	PAK1	S100	R97W	97	Missense	distal	-3	no	19.378	11.818	EPSD	TCGA;COSMIC	19.028	Loss
STE_STE20_PAKA_PAK1_ST	Q13363	CTBP1	Q13153	PAK1	S100	R93H	93	Missense	distal	-7	no	19.378	18.028	EPSD	TCGA;COSMIC	19.028	Loss
STE_STE20_PAKA_PAK1_ST	Q13363	CTBP1	Q13153	PAK1	S100	V96I	96	Missense	distal	-4	no	19.378	19.707	EPSD	TCGA	19.028	Up-regulation
STE_STE20_PAKA_PAK1_ST	Q13363	CTBP1	Q13153	PAK1	T144	R142Q	142	Missense	proximal	-2	no	19.905	10.698	EPSD	TCGA;COSMIC	19.028	Loss
STE_STE20_PAKA_PAK1_ST	Q13363	CTBP1	Q13153	PAK1	S158	R155Q	155	Missense	distal	-3	no	24.346	15.622	PhosphoSitePlus	TCGA	19.028	Loss
STE_STE20_PAKA_PAK1_ST	Q8IYU2	HACE1	Q13153	PAK1	S385	K380N	380	Missense	distal	-5	no	27.095	27.614	PhosphoSitePlus	TCGA;ICGC;COSMIC	19.028	Up-regulation
STE_STE20_PAKA_PAK1_ST	Q8IYU2	HACE1	Q13153	PAK1	T386	K380N	380	Missense	distal	-6	no	19.413	19.834	EPSD	TCGA;ICGC;COSMIC	19.028	Up-regulation
STE_STE20_PAKA_PAK1_ST	P03372	ESR1	Q13153	PAK1	S10	A9T	9	Missense	proximal	-1	no	16.173	19.203	EPSD	TCGA;COSMIC	19.028	Gain
STE_STE20_PAKA_PAK1_ST	P03372	ESR1	Q13153	PAK1	S154	P152T	152	Missense	proximal	-2	no	26.206	24.868	EPSD	TCGA;ICGC;COSMIC	19.028	Down-regulation
STE_STE20_PAKA_PAK1_ST	P03372	ESR1	Q13153	PAK1	S167	A166S	166	Missense	proximal	-1	no	18.361	20.911	EPSD	TCGA;ICGC;COSMIC	19.028	Gain
STE_STE20_PAKA_PAK1_ST	P03372	ESR1	Q13153	PAK1	S167	K171M	171	Missense	distal	4	no	18.361	19.684	EPSD	TCGA;ICGC;COSMIC	19.028	Gain
STE_STE20_PAKA_PAK1_ST	P03372	ESR1	Q13153	PAK1	S212	K206R	206	Missense	distal	-6	no	20.050	22.108	EPSD	TCGA;ICGC;COSMIC	19.028	Up-regulation
STE_STE20_PAKA_PAK1_ST	P03372	ESR1	Q13153	PAK1	S212	N217S	217	Missense	distal	5	no	20.050	20.030	EPSD	TCGA;ICGC;COSMIC	19.028	Down-regulation
STE_STE20_PAKA_PAK1_ST	P03372	ESR1	Q13153	PAK1	S212	D218N	218	Missense	distal	6	no	20.050	20.195	EPSD	TCGA;ICGC;COSMIC	19.028	Up-regulation
STE_STE20_PAKA_PAK1_ST	P03372	ESR1	Q13153	PAK1	S212	A207T	207	Missense	distal	-5	no	20.050	19.852	EPSD	TCGA;ICGC;COSMIC	19.028	Down-regulation
STE_STE20_PAKA_PAK1_ST	P03372	ESR1	Q13153	PAK1	S236	K235N	235	Missense	proximal	-1	no	25.537	22.184	EPSD	TCGA;ICGC;COSMIC	19.028	Down-regulation
STE_STE20_PAKA_PAK1_ST	P03372	ESR1	Q13153	PAK1	S236	A239S	239	Missense	distal	3	no	25.537	23.824	EPSD	TCGA;ICGC;COSMIC	19.028	Down-regulation
STE_STE20_PAKA_PAK1_ST	P03372	ESR1	Q13153	PAK1	S236	R243H	243	Missense	distal	7	no	25.537	25.585	EPSD	TCGA;ICGC;COSMIC	19.028	Up-regulation
STE_STE20_PAKA_PAK1_ST	P03372	ESR1	Q13153	PAK1	S236	R243C	243	Missense	distal	7	no	25.537	25.775	EPSD	TCGA;ICGC;COSMIC	19.028	Up-regulation
STE_STE20_PAKA_PAK1_ST	P03372	ESR1	Q13153	PAK1	S236	C240Y	240	Missense	distal	4	no	25.537	26.076	EPSD	TCGA;ICGC;COSMIC	19.028	Up-regulation
STE_STE20_PAKA_PAK1_ST	P03372	ESR1	Q13153	PAK1	S294	W292R	292	Missense	proximal	-2	no	9.192	22.131	EPSD	TCGA;ICGC;COSMIC	19.028	Gain
STE_STE20_PAKA_PAK1_ST	P03372	ESR1	Q13153	PAK1	S305	I298M	298	Missense	distal	-7	no	23.459	22.654	PhosphoSitePlus	TCGA;ICGC;COSMIC	19.028	Down-regulation
STE_STE20_PAKA_PAK1_ST	P03372	ESR1	Q13153	PAK1	S305	A307S	307	Missense	proximal	2	no	23.459	22.554	PhosphoSitePlus	TCGA;ICGC;COSMIC	19.028	Down-regulation
STE_STE20_PAKA_PAK1_ST	P03372	ESR1	Q13153	PAK1	S305	T311M	311	Missense	distal	6	no	23.459	24.316	PhosphoSitePlus	TCGA;ICGC;COSMIC	19.028	Up-regulation
STE_STE20_PAKA_PAK1_ST	P03372	ESR1	Q13153	PAK1	S554	R548H	548	Missense	distal	-6	no	22.051	21.193	EPSD	TCGA;ICGC;COSMIC	19.028	Down-regulation
STE_STE20_PAKA_PAK1_ST	P03372	ESR1	Q13153	PAK1	S554	R548C	548	Missense	distal	-6	no	22.051	18.346	EPSD	TCGA;ICGC;COSMIC;GDSC;CCLE	19.028	Loss
STE_STE20_PAKA_PAK1_ST	P03372	ESR1	Q13153	PAK1	S554	A551E	551	Missense	distal	-3	no	22.051	13.696	EPSD	TCGA;ICGC;COSMIC	19.028	Loss
STE_STE20_PAKA_PAK1_ST	P03372	ESR1	Q13153	PAK1	S554	A551V	551	Missense	distal	-3	no	22.051	14.789	EPSD	TCGA;ICGC;COSMIC;CCLE	19.028	Loss
STE_STE20_PAKA_PAK1_ST	P03372	ESR1	Q13153	PAK1	S554	R555C	555	Missense	proximal	1	no	22.051	21.607	EPSD	TCGA;ICGC;COSMIC	19.028	Down-regulation
STE_STE20_PAKA_PAK1_ST	P03372	ESR1	Q13153	PAK1	S554	R555H	555	Missense	proximal	1	no	22.051	21.789	EPSD	TCGA;ICGC;COSMIC;GDSC	19.028	Down-regulation
STE_STE20_PAKA_PAK1_ST	Q15746	MYLK	Q13153	PAK1	S145	R152H	152	Missense	distal	7	no	22.803	22.850	EPSD	TCGA;ICGC;COSMIC;GDSC	19.028	Up-regulation
STE_STE20_PAKA_PAK1_ST	Q15746	MYLK	Q13153	PAK1	S145	R152C	152	Missense	distal	7	no	22.803	23.041	EPSD	TCGA;ICGC;COSMIC	19.028	Up-regulation
STE_STE20_PAKA_PAK1_ST	Q15746	MYLK	Q13153	PAK1	S145	G141E	141	Missense	distal	-4	no	22.803	23.404	EPSD	TCGA;ICGC;COSMIC	19.028	Up-regulation
STE_STE20_PAKA_PAK1_ST	Q15746	MYLK	Q13153	PAK1	S145	R143K	143	Missense	proximal	-2	no	22.803	18.766	EPSD	TCGA;ICGC	19.028	Loss
STE_STE20_PAKA_PAK1_ST	Q15746	MYLK	Q13153	PAK1	S259	N257K	257	Missense	proximal	-2	no	18.258	19.815	EPSD	TCGA;ICGC;COSMIC	19.028	Gain
STE_STE20_PAKA_PAK1_ST	Q15746	MYLK	Q13153	PAK1	S343	A350T	350	Missense	distal	7	no	20.279	19.984	EPSD	TCGA;ICGC;COSMIC	19.028	Down-regulation
STE_STE20_PAKA_PAK1_ST	Q15746	MYLK	Q13153	PAK1	S343	A350S	350	Missense	distal	7	no	20.279	20.258	EPSD	TCGA;ICGC;COSMIC	19.028	Down-regulation
STE_STE20_PAKA_PAK1_ST	Q15746	MYLK	Q13153	PAK1	S343	A350P	350	Missense	distal	7	no	20.279	20.333	EPSD	TCGA;ICGC;COSMIC	19.028	Up-regulation
STE_STE20_PAKA_PAK1_ST	Q15746	MYLK	Q13153	PAK1	S343	T341N	341	Missense	proximal	-2	no	20.279	19.547	EPSD	TCGA;ICGC	19.028	Down-regulation
STE_STE20_PAKA_PAK1_ST	Q15746	MYLK	Q13153	PAK1	S365	R371K	371	Missense	distal	6	no	19.213	19.689	EPSD	TCGA;ICGC;COSMIC	19.028	Up-regulation
STE_STE20_PAKA_PAK1_ST	Q15746	MYLK	Q13153	PAK1	S422	E417D	417	Missense	distal	-5	no	21.528	21.955	EPSD	TCGA;ICGC;COSMIC	19.028	Up-regulation
STE_STE20_PAKA_PAK1_ST	Q15746	MYLK	Q13153	PAK1	S422	E417K	417	Missense	distal	-5	no	21.528	21.589	EPSD	TCGA;ICGC;COSMIC	19.028	Up-regulation
STE_STE20_PAKA_PAK1_ST	Q15746	MYLK	Q13153	PAK1	S422	E427K	427	Missense	distal	5	no	21.528	21.535	EPSD	TCGA;ICGC;COSMIC	19.028	Up-regulation
STE_STE20_PAKA_PAK1_ST	Q15746	MYLK	Q13153	PAK1	S422	V425I	425	Missense	distal	3	no	21.528	21.609	EPSD	TCGA;ICGC;COSMIC	19.028	Up-regulation
STE_STE20_PAKA_PAK1_ST	Q15746	MYLK	Q13153	PAK1	S422	E424D	424	Missense	proximal	2	no	21.528	21.838	EPSD	TCGA;ICGC;COSMIC	19.028	Up-regulation
STE_STE20_PAKA_PAK1_ST	Q15746	MYLK	Q13153	PAK1	S848	G842S	842	Missense	distal	-6	no	23.409	23.695	EPSD	TCGA;ICGC;COSMIC	19.028	Up-regulation
STE_STE20_PAKA_PAK1_ST	Q15746	MYLK	Q13153	PAK1	S947	D952N	952	Missense	distal	5	no	19.631	19.643	EPSD	TCGA;ICGC;COSMIC	19.028	Up-regulation
STE_STE20_PAKA_PAK1_ST	Q15746	MYLK	Q13153	PAK1	S947	E940Q	940	Missense	distal	-7	no	19.631	18.998	EPSD	TCGA;ICGC;COSMIC	19.028	Loss
STE_STE20_PAKA_PAK1_ST	Q15746	MYLK	Q13153	PAK1	S947	D952A	952	Missense	distal	5	no	19.631	19.637	EPSD	TCGA;ICGC;COSMIC	19.028	Up-regulation
STE_STE20_PAKA_PAK1_ST	Q15746	MYLK	Q13153	PAK1	S947	E942K	942	Missense	distal	-5	no	19.631	19.691	EPSD	TCGA;ICGC;COSMIC	19.028	Up-regulation
STE_STE20_PAKA_PAK1_ST	Q15746	MYLK	Q13153	PAK1	S947	R954C	954	Missense	distal	7	no	19.631	19.869	EPSD	TCGA;ICGC;COSMIC	19.028	Up-regulation
STE_STE20_PAKA_PAK1_ST	Q15746	MYLK	Q13153	PAK1	S947	E940D	940	Missense	distal	-7	no	19.631	18.691	EPSD	TCGA;ICGC;COSMIC	19.028	Loss
STE_STE20_PAKA_PAK1_ST	Q15746	MYLK	Q13153	PAK1	S1208	R1204W	1204	Missense	distal	-4	no	28.909	27.925	EPSD	TCGA;ICGC;COSMIC	19.028	Down-regulation
STE_STE20_PAKA_PAK1_ST	Q15746	MYLK	Q13153	PAK1	S1208	V1213M	1213	Missense	distal	5	no	28.909	28.925	EPSD	TCGA;ICGC;COSMIC;GDSC	19.028	Up-regulation
STE_STE20_PAKA_PAK1_ST	Q15746	MYLK	Q13153	PAK1	S1208	R1204Q	1204	Missense	distal	-4	no	28.909	28.441	EPSD	TCGA;ICGC;COSMIC	19.028	Down-regulation
STE_STE20_PAKA_PAK1_ST	Q15746	MYLK	Q13153	PAK1	S1209	R1204W	1204	Missense	distal	-5	no	20.433	21.562	EPSD	TCGA;ICGC;COSMIC	19.028	Up-regulation
STE_STE20_PAKA_PAK1_ST	Q15746	MYLK	Q13153	PAK1	S1209	V1213M	1213	Missense	distal	4	no	20.433	20.536	EPSD	TCGA;ICGC;COSMIC;GDSC	19.028	Up-regulation
STE_STE20_PAKA_PAK1_ST	Q15746	MYLK	Q13153	PAK1	S1209	R1204Q	1204	Missense	distal	-5	no	20.433	20.532	EPSD	TCGA;ICGC;COSMIC	19.028	Up-regulation
STE_STE20_PAKA_PAK1_ST	Q15746	MYLK	Q13153	PAK1	S1570	S1570L	1570	Missense	central	0	yes	21.141	0.000	EPSD	TCGA;ICGC;COSMIC	19.028	Loss
STE_STE20_PAKA_PAK1_ST	Q15746	MYLK	Q13153	PAK1	S1570	E1571K	1571	Missense	proximal	1	no	21.141	21.011	EPSD	TCGA;ICGC;COSMIC	19.028	Down-regulation
STE_STE20_PAKA_PAK1_ST	Q15746	MYLK	Q13153	PAK1	S1570	R1567Q	1567	Missense	distal	-3	no	21.141	12.417	EPSD	TCGA;ICGC;COSMIC	19.028	Loss
STE_STE20_PAKA_PAK1_ST	Q15746	MYLK	Q13153	PAK1	S1570	R1567W	1567	Missense	distal	-3	no	21.141	13.580	EPSD	TCGA;ICGC	19.028	Loss
STE_STE20_PAKA_PAK1_ST	Q15746	MYLK	Q13153	PAK1	S1759	S1759Y	1759	Missense	central	0	yes	24.753	0.000	EPSD	TCGA;ICGC;COSMIC	19.028	Loss
STE_STE20_PAKA_PAK1_ST	Q15746	MYLK	Q13153	PAK1	S1759	M1763I	1763	Missense	distal	4	no	24.753	24.549	EPSD	TCGA;COSMIC	19.028	Down-regulation
STE_STE20_PAKA_PAK1_ST	Q15746	MYLK	Q13153	PAK1	S1760	S1759Y	1759	Missense	proximal	-1	no	25.701	24.821	EPSD	TCGA;ICGC;COSMIC	19.028	Down-regulation
STE_STE20_PAKA_PAK1_ST	Q15746	MYLK	Q13153	PAK1	S1760	L1767I	1767	Missense	distal	7	no	25.701	25.672	EPSD	TCGA	19.028	Down-regulation
STE_STE20_PAKA_PAK1_ST	Q15746	MYLK	Q13153	PAK1	S1760	M1763I	1763	Missense	distal	3	no	25.701	25.349	EPSD	TCGA;COSMIC	19.028	Down-regulation
STE_STE20_PAKA_PAK1_ST	Q15746	MYLK	Q13153	PAK1	S1772	L1767I	1767	Missense	distal	-5	no	20.841	20.503	PhosphoSitePlus	TCGA	19.028	Down-regulation
STE_STE20_PAKA_PAK1_ST	Q15746	MYLK	Q13153	PAK1	S1773	P1780S	1780	Missense	distal	7	no	22.812	22.738	EPSD	TCGA;COSMIC	19.028	Down-regulation
STE_STE20_PAKA_PAK1_ST	Q15746	MYLK	Q13153	PAK1	S1773	L1767I	1767	Missense	distal	-6	no	22.812	21.958	EPSD	TCGA	19.028	Down-regulation
STE_STE20_PAKA_PAK1_ST	Q15746	MYLK	Q13153	PAK1	T1774	P1780S	1780	Missense	distal	6	no	21.034	20.786	EPSD	TCGA;COSMIC	19.028	Down-regulation
STE_STE20_PAKA_PAK1_ST	Q15746	MYLK	Q13153	PAK1	T1774	L1767I	1767	Missense	distal	-7	no	21.034	20.909	EPSD	TCGA	19.028	Down-regulation
STE_STE20_PAKA_PAK1_ST	P08670	VIM	Q13153	PAK1	S26	S22I	22	Missense	distal	-4	no	24.597	24.835	EPSD	TCGA;ICGC;COSMIC	19.028	Up-regulation
STE_STE20_PAKA_PAK1_ST	P08670	VIM	Q13153	PAK1	S26	T33M	33	Missense	distal	7	no	24.597	25.027	EPSD	TCGA;ICGC;COSMIC	19.028	Up-regulation
STE_STE20_PAKA_PAK1_ST	P08670	VIM	Q13153	PAK1	S27	S22I	22	Missense	distal	-5	no	18.957	19.379	EPSD	TCGA;ICGC;COSMIC	19.028	Gain
STE_STE20_PAKA_PAK1_ST	P08670	VIM	Q13153	PAK1	S27	T33M	33	Missense	distal	6	no	18.957	19.814	EPSD	TCGA;ICGC;COSMIC	19.028	Gain
STE_STE20_PAKA_PAK1_ST	P08670	VIM	Q13153	PAK1	T35	T33M	33	Missense	proximal	-2	no	19.576	20.200	EPSD	TCGA;ICGC;COSMIC	19.028	Up-regulation
STE_STE20_PAKA_PAK1_ST	P08670	VIM	Q13153	PAK1	S39	T33M	33	Missense	distal	-6	no	23.474	22.100	EPSD	TCGA;ICGC;COSMIC	19.028	Down-regulation
STE_STE20_PAKA_PAK1_ST	P08670	VIM	Q13153	PAK1	S51	R50H	50	Missense	proximal	-1	no	20.183	17.375	EPSD	TCGA;ICGC;COSMIC	19.028	Loss
STE_STE20_PAKA_PAK1_ST	P08670	VIM	Q13153	PAK1	S51	P57L	57	Missense	distal	6	no	20.183	20.207	EPSD	TCGA;ICGC;COSMIC;CCLE	19.028	Up-regulation
STE_STE20_PAKA_PAK1_ST	P08670	VIM	Q13153	PAK1	S51	P57R	57	Missense	distal	6	no	20.183	19.670	EPSD	TCGA;ICGC;COSMIC	19.028	Down-regulation
STE_STE20_PAKA_PAK1_ST	P08670	VIM	Q13153	PAK1	S56	R50H	50	Missense	distal	-6	no	22.375	21.516	PhosphoSitePlus	TCGA;ICGC;COSMIC	19.028	Down-regulation
STE_STE20_PAKA_PAK1_ST	P08670	VIM	Q13153	PAK1	S56	P57L	57	Missense	proximal	1	no	22.375	22.662	PhosphoSitePlus	TCGA;ICGC;COSMIC;CCLE	19.028	Up-regulation
STE_STE20_PAKA_PAK1_ST	P08670	VIM	Q13153	PAK1	S56	P57R	57	Missense	proximal	1	no	22.375	22.894	PhosphoSitePlus	TCGA;ICGC;COSMIC	19.028	Up-regulation
STE_STE20_PAKA_PAK1_ST	P08670	VIM	Q13153	PAK1	S66	R71W	71	Missense	distal	5	no	25.465	25.495	EPSD	TCGA;ICGC;COSMIC	19.028	Up-regulation
STE_STE20_PAKA_PAK1_ST	P08670	VIM	Q13153	PAK1	S72	R71W	71	Missense	proximal	-1	no	22.107	18.486	EPSD	TCGA;ICGC;COSMIC	19.028	Loss
STE_STE20_PAKA_PAK1_ST	P08670	VIM	Q13153	PAK1	S73	R71W	71	Missense	proximal	-2	no	30.109	17.170	EPSD	TCGA;ICGC;COSMIC	19.028	Loss
STE_STE20_PAKA_PAK1_ST	P08670	VIM	Q13153	PAK1	S293	E288D	288	Missense	distal	-5	no	18.644	19.070	EPSD	TCGA	19.028	Gain
STE_STE20_PAKA_PAK1_ST	P08670	VIM	Q13153	PAK1	S412	E407K	407	Missense	distal	-5	no	22.616	22.676	EPSD	TCGA;ICGC;COSMIC	19.028	Up-regulation
STE_STE20_PAKA_PAK1_ST	P08670	VIM	Q13153	PAK1	S412	E407V	407	Missense	distal	-5	no	22.616	23.062	EPSD	TCGA;ICGC	19.028	Up-regulation
STE_STE20_PAKA_PAK1_ST	P08670	VIM	Q13153	PAK1	S412	E407D	407	Missense	distal	-5	no	22.616	23.042	EPSD	TCGA;ICGC;COSMIC	19.028	Up-regulation
STE_STE20_PAKA_PAK1_ST	P08670	VIM	Q13153	PAK1	T426	D429Y	429	Missense	distal	3	no	18.484	20.820	EPSD	TCGA;ICGC;COSMIC	19.028	Gain
Atypical_Alpha_ChaK_TRPM6_ST	Q9BX84	TRPM6	Q9BX84	TRPM6	T693	R689C	689	Missense	distal	-4	no	1.117	1.057	EPSD	TCGA;COSMIC	1.085	Loss
Atypical_Alpha_ChaK_TRPM6_ST	Q9BX84	TRPM6	Q9BX84	TRPM6	T693	R689H	689	Missense	distal	-4	no	1.117	1.089	EPSD	TCGA;COSMIC	1.085	Down-regulation
Atypical_Alpha_ChaK_TRPM6_ST	Q9BX84	TRPM6	Q9BX84	TRPM6	T693	E698K	698	Missense	distal	5	no	1.117	1.095	EPSD	TCGA;COSMIC	1.085	Down-regulation
Atypical_Alpha_ChaK_TRPM6_ST	Q9BX84	TRPM6	Q9BX84	TRPM6	T696	R689C	689	Missense	distal	-7	no	1.751	1.887	EPSD	TCGA;COSMIC	1.085	Up-regulation
Atypical_Alpha_ChaK_TRPM6_ST	Q9BX84	TRPM6	Q9BX84	TRPM6	T696	R689H	689	Missense	distal	-7	no	1.751	1.806	EPSD	TCGA;COSMIC	1.085	Up-regulation
Atypical_Alpha_ChaK_TRPM6_ST	Q9BX84	TRPM6	Q9BX84	TRPM6	T696	E698K	698	Missense	proximal	2	no	1.751	1.772	EPSD	TCGA;COSMIC	1.085	Up-regulation
Atypical_Alpha_ChaK_TRPM6_ST	Q9BX84	TRPM6	Q9BX84	TRPM6	S1560	S1562C	1562	Missense	proximal	2	no	1.569	1.571	EPSD	TCGA;COSMIC	1.085	Up-regulation
Atypical_Alpha_ChaK_TRPM6_ST	Q9BX84	TRPM6	Q9BX84	TRPM6	T1851	Q1850H	1850	Missense	proximal	-1	no	5.933	5.737	PhosphoSitePlus	TCGA;COSMIC	1.085	Down-regulation
Atypical_Alpha_ChaK_TRPM6_ST	Q9BX84	TRPM6	Q9BX84	TRPM6	T1851	Q1846H	1846	Missense	distal	-5	no	5.933	5.975	PhosphoSitePlus	TCGA;COSMIC	1.085	Up-regulation
Atypical_Alpha_ChaK_TRPM6_ST	Q9BX84	TRPM6	Q9BX84	TRPM6	T1851	P1853S	1853	Missense	proximal	2	no	5.933	5.909	PhosphoSitePlus	TCGA;COSMIC	1.085	Down-regulation
Other_WNK_WNK1_ST	O94913	PCF11	Q9H4A3	WNK1	S33	S33R	33	Missense	central	0	yes	0.000	0.000	EPSD	TCGA;ICGC;COSMIC	0.000	Loss
Other_WNK_WNK1_ST	O94913	PCF11	Q9H4A3	WNK1	S56	S56C	56	Missense	central	0	yes	0.000	0.000	EPSD	TCGA;ICGC;COSMIC	0.000	Loss
Other_WNK_WNK1_ST	O94913	PCF11	Q9H4A3	WNK1	S120	S120Y	120	Missense	central	0	yes	0.001	0.000	PhosphoSitePlus;EPSD	TCGA;ICGC	0.000	Loss
Other_WNK_WNK1_ST	O94913	PCF11	Q9H4A3	WNK1	S120	R119C	119	Missense	proximal	-1	no	0.001	0.000	PhosphoSitePlus;EPSD	TCGA;ICGC;COSMIC	0.000	Down-regulation
Other_WNK_WNK1_ST	O94913	PCF11	Q9H4A3	WNK1	S120	R119H	119	Missense	proximal	-1	no	0.001	0.000	PhosphoSitePlus;EPSD	TCGA;ICGC	0.000	Down-regulation
Other_WNK_WNK1_ST	O94913	PCF11	Q9H4A3	WNK1	T121	S120Y	120	Missense	proximal	-1	no	0.001	0.000	EPSD;PhosphoSitePlus	TCGA;ICGC	0.000	Down-regulation
Other_WNK_WNK1_ST	O94913	PCF11	Q9H4A3	WNK1	T121	R119C	119	Missense	proximal	-2	no	0.001	0.000	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	0.000	Down-regulation
Other_WNK_WNK1_ST	O94913	PCF11	Q9H4A3	WNK1	T121	R119H	119	Missense	proximal	-2	no	0.001	0.000	EPSD;PhosphoSitePlus	TCGA;ICGC	0.000	Down-regulation
Other_WNK_WNK1_ST	O94913	PCF11	Q9H4A3	WNK1	S181	P188L	188	Missense	distal	7	no	-0.001	0.000	EPSD	TCGA;ICGC;COSMIC;GDSC;CCLE	0.000	Gain
Other_WNK_WNK1_ST	O94913	PCF11	Q9H4A3	WNK1	S312	S312N	312	Missense	central	0	yes	0.000	0.000	EPSD	TCGA;ICGC	0.000	Loss
Other_WNK_WNK1_ST	O94913	PCF11	Q9H4A3	WNK1	S364	S364L	364	Missense	central	0	yes	0.000	0.000	EPSD	TCGA;ICGC;COSMIC;GDSC;CCLE	0.000	Loss
Other_WNK_WNK1_ST	O94913	PCF11	Q9H4A3	WNK1	S368	S368L	368	Missense	central	0	yes	0.001	0.000	EPSD	TCGA;ICGC	0.000	Loss
Other_WNK_WNK1_ST	O94913	PCF11	Q9H4A3	WNK1	S368	D361Y	361	Missense	distal	-7	no	0.001	0.000	EPSD	TCGA;ICGC;COSMIC	0.000	Down-regulation
Other_WNK_WNK1_ST	O94913	PCF11	Q9H4A3	WNK1	S389	Q387K	387	Missense	proximal	-2	no	0.000	0.001	EPSD	TCGA;ICGC;COSMIC	0.000	Up-regulation
Other_WNK_WNK1_ST	O94913	PCF11	Q9H4A3	WNK1	T459	K466N	466	Missense	distal	7	no	0.001	0.000	EPSD	TCGA;ICGC;COSMIC	0.000	Down-regulation
Other_WNK_WNK1_ST	O94913	PCF11	Q9H4A3	WNK1	S502	R501W	501	Missense	proximal	-1	no	0.001	0.000	EPSD	TCGA;ICGC;COSMIC	0.000	Down-regulation
Other_WNK_WNK1_ST	O94913	PCF11	Q9H4A3	WNK1	S511	R505Q	505	Missense	distal	-6	no	0.001	0.000	EPSD	TCGA;ICGC;COSMIC	0.000	Down-regulation
Other_WNK_WNK1_ST	O94913	PCF11	Q9H4A3	WNK1	S606	S606R	606	Missense	central	0	yes	0.000	0.000	EPSD	TCGA	0.000	Loss
Other_WNK_WNK1_ST	O94913	PCF11	Q9H4A3	WNK1	S633	S633P	633	Missense	central	0	yes	0.000	0.000	EPSD	TCGA;ICGC;COSMIC	0.000	Loss
Other_WNK_WNK1_ST	O94913	PCF11	Q9H4A3	WNK1	T1211	M1210I	1210	Missense	proximal	-1	no	0.000	-0.001	EPSD	TCGA;ICGC;COSMIC	0.000	Loss
Other_WNK_WNK1_ST	O94913	PCF11	Q9H4A3	WNK1	S1543	S1543F	1543	Missense	central	0	yes	0.000	0.000	EPSD	TCGA;ICGC;COSMIC	0.000	Loss
Other_WNK_WNK1_ST	O94913	PCF11	Q9H4A3	WNK1	S1554	E1553K	1553	Missense	proximal	-1	no	0.000	0.001	EPSD	TCGA;ICGC;COSMIC	0.000	Up-regulation
Other_WNK_WNK1_ST	O95747	OXSR1	Q9H4A3	WNK1	T185	R179Q	179	Missense	distal	-6	no	0.002	0.001	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	0.000	Down-regulation
Other_WNK_WNK1_ST	O95747	OXSR1	Q9H4A3	WNK1	T189	G188D	188	Missense	proximal	-1	no	0.000	0.001	EPSD	TCGA;ICGC;COSMIC	0.000	Up-regulation
Other_WNK_WNK1_ST	O95747	OXSR1	Q9H4A3	WNK1	S263	S263L	263	Missense	central	0	yes	0.001	0.000	EPSD	TCGA;ICGC;COSMIC	0.000	Loss
Other_WNK_WNK1_ST	O95747	OXSR1	Q9H4A3	WNK1	S269	S269L	269	Missense	central	0	yes	0.000	0.000	EPSD	TCGA;ICGC;COSMIC	0.000	Loss
Other_WNK_WNK1_ST	O95747	OXSR1	Q9H4A3	WNK1	S324	S324F	324	Missense	central	0	yes	0.000	0.000	EPSD	TCGA;ICGC;COSMIC	0.000	Loss
Other_WNK_WNK1_ST	O95747	OXSR1	Q9H4A3	WNK1	T331	K330N	330	Missense	proximal	-1	no	0.001	0.000	EPSD	TCGA;ICGC;COSMIC	0.000	Down-regulation
Other_WNK_WNK1_ST	O95747	OXSR1	Q9H4A3	WNK1	S339	F343L	343	Missense	distal	4	no	0.000	0.001	EPSD	TCGA;ICGC;COSMIC	0.000	Up-regulation
Other_WNK_WNK1_ST	O95747	OXSR1	Q9H4A3	WNK1	S339	G335V	335	Missense	distal	-4	no	0.000	0.001	EPSD	TCGA;ICGC;COSMIC	0.000	Up-regulation
Other_WNK_WNK1_ST	O95747	OXSR1	Q9H4A3	WNK1	S423	S423L	423	Missense	central	0	yes	0.000	0.000	EPSD	TCGA;ICGC;COSMIC	0.000	Loss
Other_WNK_WNK1_ST	Q9H4A3	WNK1	Q9H4A3	WNK1	T74	T74A	74	Missense	central	0	yes	0.000	0.000	EPSD	TCGA;ICGC;COSMIC	0.000	Loss
Other_WNK_WNK1_ST	Q9H4A3	WNK1	Q9H4A3	WNK1	S382	R376W	376	Missense	distal	-6	no	0.002	0.001	PhosphoSitePlus	TCGA;ICGC	0.000	Down-regulation
Other_WNK_WNK1_ST	Q9H4A3	WNK1	Q9H4A3	WNK1	S587	E586D	586	Missense	proximal	-1	no	0.000	0.001	EPSD	TCGA;ICGC;COSMIC	0.000	Up-regulation
Other_WNK_WNK1_ST	Q9H4A3	WNK1	Q9H4A3	WNK1	S587	E586K	586	Missense	proximal	-1	no	0.000	0.001	EPSD	TCGA;COSMIC	0.000	Up-regulation
Other_WNK_WNK1_ST	Q9H4A3	WNK1	Q9H4A3	WNK1	S1110	R1109L	1109	Missense	proximal	-1	no	0.001	0.000	EPSD	TCGA;COSMIC	0.000	Down-regulation
Other_WNK_WNK1_ST	Q9H4A3	WNK1	Q9H4A3	WNK1	S1110	R1109H	1109	Missense	proximal	-1	no	0.001	0.000	EPSD	TCGA	0.000	Down-regulation
Other_WNK_WNK1_ST	Q9H4A3	WNK1	Q9H4A3	WNK1	T1115	R1109L	1109	Missense	distal	-6	no	0.001	0.000	EPSD	TCGA;COSMIC	0.000	Down-regulation
Other_WNK_WNK1_ST	Q9H4A3	WNK1	Q9H4A3	WNK1	T1115	R1109H	1109	Missense	distal	-6	no	0.001	0.000	EPSD	TCGA	0.000	Down-regulation
Other_WNK_WNK1_ST	Q9H4A3	WNK1	Q9H4A3	WNK1	S1246	S1246Y	1246	Missense	central	0	yes	0.000	0.000	EPSD	TCGA;COSMIC	0.000	Loss
Other_WNK_WNK1_ST	Q9H4A3	WNK1	Q9H4A3	WNK1	S1253	S1253F	1253	Missense	central	0	yes	0.000	0.000	EPSD	TCGA;COSMIC	0.000	Loss
Other_WNK_WNK1_ST	Q9H4A3	WNK1	Q9H4A3	WNK1	S1289	S1289N	1289	Missense	central	0	yes	0.000	0.000	EPSD	TCGA	0.000	Loss
Other_WNK_WNK1_ST	Q9H4A3	WNK1	Q9H4A3	WNK1	S1300	S1300C	1300	Missense	central	0	yes	0.000	0.000	EPSD	TCGA;COSMIC	0.000	Loss
Other_WNK_WNK1_ST	Q9H4A3	WNK1	Q9H4A3	WNK1	S1300	S1300P	1300	Missense	central	0	yes	0.000	0.000	EPSD	TCGA;COSMIC	0.000	Loss
Other_WNK_WNK1_ST	Q9H4A3	WNK1	Q9H4A3	WNK1	S1528	K1531N	1531	Missense	distal	3	no	-0.001	0.000	EPSD	TCGA;COSMIC	0.000	Gain
Other_WNK_WNK1_ST	Q9H4A3	WNK1	Q9H4A3	WNK1	S1528	V1523A	1523	Missense	distal	-5	no	-0.001	0.000	EPSD	TCGA;COSMIC	0.000	Gain
Other_WNK_WNK1_ST	Q9H4A3	WNK1	Q9H4A3	WNK1	S1882	S1882F	1882	Missense	central	0	yes	0.000	0.000	EPSD	TCGA;COSMIC	0.000	Loss
Other_WNK_WNK1_ST	Q9H4A3	WNK1	Q9H4A3	WNK1	T1963	R1957C	1957	Missense	distal	-6	no	0.001	0.000	EPSD	TCGA;COSMIC	0.000	Down-regulation
Other_WNK_WNK1_ST	Q9H4A3	WNK1	Q9H4A3	WNK1	T1963	R1957H	1957	Missense	distal	-6	no	0.001	0.000	EPSD	TCGA;COSMIC	0.000	Down-regulation
Other_WNK_WNK1_ST	Q9H4A3	WNK1	Q9H4A3	WNK1	T1970	T1970P	1970	Missense	central	0	yes	0.000	0.000	EPSD	TCGA;COSMIC	0.000	Loss
Other_WNK_WNK1_ST	Q9H4A3	WNK1	Q9H4A3	WNK1	S1978	K1972N	1972	Missense	distal	-6	no	0.001	0.000	EPSD	TCGA;COSMIC	0.000	Down-regulation
Other_WNK_WNK1_ST	Q9H4A3	WNK1	Q9H4A3	WNK1	S2029	G2028S	2028	Missense	proximal	-1	no	-0.001	0.000	EPSD	TCGA;GDSC;CCLE	0.000	Gain
Other_WNK_WNK1_ST	Q9H4A3	WNK1	Q9H4A3	WNK1	S2145	S2145N	2145	Missense	central	0	yes	0.000	0.000	EPSD	TCGA;COSMIC	0.000	Loss
Other_WNK_WNK1_ST	Q9H4A3	WNK1	Q9H4A3	WNK1	S2265	S2265L	2265	Missense	central	0	yes	0.000	0.000	EPSD	TCGA;COSMIC	0.000	Loss
Other_WNK_WNK1_ST	Q9H4A3	WNK1	Q9H4A3	WNK1	S2370	S2370F	2370	Missense	central	0	yes	0.000	0.000	EPSD	TCGA;COSMIC	0.000	Loss
Other_WNK_WNK1_ST	Q9UHW9	SLC12A6	Q9H4A3	WNK1	S36	S36R	36	Missense	central	0	yes	0.000	0.000	EPSD	TCGA;ICGC;COSMIC	0.000	Loss
Other_WNK_WNK1_ST	Q9UHW9	SLC12A6	Q9H4A3	WNK1	T67	A66V	66	Missense	proximal	-1	no	0.001	0.000	EPSD	TCGA;COSMIC	0.000	Down-regulation
Other_WNK_WNK1_ST	Q9UHW9	SLC12A6	Q9H4A3	WNK1	S96	S96P	96	Missense	central	0	yes	0.000	0.000	EPSD	TCGA;COSMIC	0.000	Loss
Other_WNK_WNK1_ST	Q9UHW9	SLC12A6	Q9H4A3	WNK1	T187	T187I	187	Missense	central	0	yes	0.000	0.000	EPSD	TCGA;COSMIC	0.000	Loss
Other_WNK_WNK1_ST	Q9UHW9	SLC12A6	Q9H4A3	WNK1	S465	S465Y	465	Missense	central	0	yes	0.000	0.000	EPSD	TCGA;COSMIC	0.000	Loss
Other_WNK_WNK1_ST	Q9UHW9	SLC12A6	Q9H4A3	WNK1	S734	S734P	734	Missense	central	0	yes	0.000	0.000	EPSD	TCGA	0.000	Loss
Other_WNK_WNK1_ST	Q9UHW9	SLC12A6	Q9H4A3	WNK1	S1032	R1026P	1026	Missense	distal	-6	no	0.001	0.000	EPSD	TCGA;COSMIC	0.000	Down-regulation
Other_WNK_WNK1_ST	Q9UEW8	STK39	Q9H4A3	WNK1	S114	V121I	121	Missense	distal	7	no	0.001	0.000	EPSD	TCGA;ICGC;COSMIC	0.000	Down-regulation
Other_WNK_WNK1_ST	Q9UEW8	STK39	Q9H4A3	WNK1	S145	S145L	145	Missense	central	0	yes	0.000	0.000	EPSD	TCGA	0.000	Loss
Other_WNK_WNK1_ST	Q9UEW8	STK39	Q9H4A3	WNK1	T231	R225Q	225	Missense	distal	-6	no	0.002	0.001	PhosphoSitePlus;EPSD	TCGA;ICGC;COSMIC	0.000	Down-regulation
Other_WNK_WNK1_ST	Q9UEW8	STK39	Q9H4A3	WNK1	S309	K312T	312	Missense	distal	3	no	0.000	0.001	EPSD	TCGA;ICGC;COSMIC	0.000	Up-regulation
Other_WNK_WNK1_ST	Q9UEW8	STK39	Q9H4A3	WNK1	T354	R353I	353	Missense	proximal	-1	no	0.001	0.000	EPSD	TCGA;ICGC;COSMIC	0.000	Down-regulation
Other_WNK_WNK1_ST	Q9UEW8	STK39	Q9H4A3	WNK1	S430	S430F	430	Missense	central	0	yes	0.000	0.000	EPSD	TCGA;ICGC;COSMIC	0.000	Loss
TK_InsR_INSR_Y	P35568	IRS1	P06213	INSR	Y431	S428L	428	Missense	distal	-3	no	13.127	8.885	EPSD	TCGA;ICGC;COSMIC	10.312	Loss
TK_InsR_INSR_Y	P35568	IRS1	P06213	INSR	Y431	G424S	424	Missense	distal	-7	no	13.127	13.713	EPSD	TCGA;ICGC;COSMIC	10.312	Up-regulation
TK_InsR_INSR_Y	P35568	IRS1	P06213	INSR	Y431	F438V	438	Missense	distal	7	no	13.127	13.133	EPSD	TCGA;ICGC;COSMIC	10.312	Up-regulation
TK_InsR_INSR_Y	P35568	IRS1	P06213	INSR	Y465	G469C	469	Missense	distal	4	no	11.422	10.956	EPSD	TCGA;ICGC;COSMIC	10.312	Down-regulation
TK_InsR_INSR_Y	P35568	IRS1	P06213	INSR	Y465	E461G	461	Missense	distal	-4	no	11.422	10.113	EPSD	TCGA;ICGC;COSMIC	10.312	Loss
TK_InsR_INSR_Y	P35568	IRS1	P06213	INSR	Y551	P556S	556	Missense	distal	5	no	10.566	9.636	EPSD	TCGA;ICGC;COSMIC	10.312	Loss
TK_InsR_INSR_Y	P35568	IRS1	P06213	INSR	Y551	S544L	544	Missense	distal	-7	no	10.566	9.255	EPSD	TCGA;ICGC;COSMIC	10.312	Loss
TK_InsR_INSR_Y	P35568	IRS1	P06213	INSR	Y551	E553D	553	Missense	proximal	2	no	10.566	10.910	EPSD	TCGA;ICGC;COSMIC	10.312	Up-regulation
TK_InsR_INSR_Y	P35568	IRS1	P06213	INSR	Y612	H607R	607	Missense	distal	-5	no	17.286	17.745	EPSD	TCGA;ICGC	10.312	Up-regulation
TK_InsR_INSR_Y	P35568	IRS1	P06213	INSR	Y612	G611C	611	Missense	proximal	-1	no	17.286	14.767	EPSD	TCGA;ICGC;COSMIC	10.312	Down-regulation
TK_InsR_INSR_Y	P35568	IRS1	P06213	INSR	Y896	E900A	900	Missense	distal	4	no	13.644	12.819	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	10.312	Down-regulation
TK_InsR_INSR_Y	P35568	IRS1	P06213	INSR	Y896	P890S	890	Missense	distal	-6	no	13.644	13.619	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	10.312	Down-regulation
TK_InsR_INSR_Y	P35568	IRS1	P06213	INSR	Y941	E939Q	939	Missense	proximal	-2	no	20.361	18.633	EPSD	TCGA;ICGC;COSMIC	10.312	Down-regulation
TK_InsR_INSR_Y	P35568	IRS1	P06213	INSR	Y941	E939K	939	Missense	proximal	-2	no	20.361	17.084	EPSD	TCGA;ICGC;COSMIC	10.312	Down-regulation
TK_InsR_INSR_Y	P35568	IRS1	P06213	INSR	Y989	R986W	986	Missense	distal	-3	no	17.668	14.297	PhosphoSitePlus;EPSD	TCGA;ICGC;COSMIC;GDSC;CCLE	10.312	Down-regulation
TK_InsR_INSR_Y	P35568	IRS1	P06213	INSR	Y1001	S1005L	1005	Missense	distal	4	no	13.473	12.323	EPSD	TCGA;ICGC	10.312	Down-regulation
TK_InsR_INSR_Y	P35568	IRS1	P06213	INSR	Y1179	I1180M	1180	Missense	proximal	1	no	15.829	16.964	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	10.312	Up-regulation
TK_InsR_INSR_Y	P35568	IRS1	P06213	INSR	Y1179	G1176S	1176	Missense	distal	-3	no	15.829	17.237	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	10.312	Up-regulation
TK_InsR_INSR_Y	P35568	IRS1	P06213	INSR	Y1229	S1223G	1223	Missense	distal	-6	no	10.599	10.616	EPSD	TCGA;ICGC;COSMIC	10.312	Up-regulation
TK_InsR_INSR_Y	P35568	IRS1	P06213	INSR	Y1229	S1233G	1233	Missense	distal	4	no	10.599	10.180	EPSD	TCGA;ICGC;COSMIC	10.312	Loss
TK_InsR_INSR_Y	P53004	BLVRA	P06213	INSR	Y83	D82G	82	Missense	proximal	-1	no	16.524	13.520	EPSD	TCGA;ICGC;COSMIC	10.312	Down-regulation
TK_InsR_INSR_Y	P53004	BLVRA	P06213	INSR	Y83	L88V	88	Missense	distal	5	no	16.524	16.200	EPSD	TCGA;ICGC;COSMIC	10.312	Down-regulation
TK_InsR_INSR_Y	P53004	BLVRA	P06213	INSR	Y198	K200E	200	Missense	proximal	2	no	12.819	13.433	EPSD;PhosphoSitePlus	TCGA;ICGC	10.312	Up-regulation
TK_InsR_INSR_Y	P53004	BLVRA	P06213	INSR	Y198	D196H	196	Missense	proximal	-2	no	12.819	6.701	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	10.312	Loss
TK_InsR_INSR_Y	P53004	BLVRA	P06213	INSR	Y198	M199I	199	Missense	proximal	1	no	12.819	11.684	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	10.312	Down-regulation
TK_InsR_INSR_Y	P53004	BLVRA	P06213	INSR	Y228	S235C	235	Missense	distal	7	no	11.369	11.359	PhosphoSitePlus;EPSD	TCGA;ICGC;COSMIC	10.312	Down-regulation
TK_InsR_INSR_Y	P53004	BLVRA	P06213	INSR	Y228	K234N	234	Missense	distal	6	no	11.369	11.515	PhosphoSitePlus;EPSD	TCGA	10.312	Up-regulation
TK_InsR_INSR_Y	P53004	BLVRA	P06213	INSR	Y228	N226H	226	Missense	proximal	-2	no	11.369	7.390	PhosphoSitePlus;EPSD	TCGA;ICGC;COSMIC	10.312	Loss
TK_InsR_INSR_Y	P53004	BLVRA	P06213	INSR	Y228	H232N	232	Missense	distal	4	no	11.369	12.004	PhosphoSitePlus;EPSD	TCGA;ICGC;COSMIC	10.312	Up-regulation
TK_InsR_INSR_Y	P06213	INSR	P06213	INSR	Y401	A402T	402	Missense	proximal	1	no	8.628	10.429	EPSD	TCGA;ICGC;COSMIC;GDSC;CCLE	10.312	Gain
TK_InsR_INSR_Y	P06213	INSR	P06213	INSR	Y401	R399Q	399	Missense	proximal	-2	no	8.628	10.323	EPSD	TCGA;ICGC;COSMIC	10.312	Gain
TK_InsR_INSR_Y	P06213	INSR	P06213	INSR	Y999	S1003N	1003	Missense	distal	4	no	12.712	12.378	EPSD;PhosphoSitePlus	TCGA	10.312	Down-regulation
TK_InsR_INSR_Y	P06213	INSR	P06213	INSR	Y999	S994F	994	Missense	distal	-5	no	12.712	10.555	EPSD;PhosphoSitePlus	TCGA;COSMIC	10.312	Down-regulation
TK_InsR_INSR_Y	P06213	INSR	P06213	INSR	Y1011	E1015K	1015	Missense	distal	4	no	10.498	9.998	EPSD;PhosphoSitePlus	TCGA;COSMIC;CCLE	10.312	Loss
TK_InsR_INSR_Y	P06213	INSR	P06213	INSR	Y1185	E1186Q	1186	Missense	proximal	1	no	13.813	12.702	EPSD;PhosphoSitePlus	TCGA;COSMIC	10.312	Down-regulation
TK_InsR_INSR_Y	P06213	INSR	P06213	INSR	Y1185	R1182G	1182	Missense	distal	-3	no	13.813	14.379	EPSD;PhosphoSitePlus	TCGA;COSMIC	10.312	Up-regulation
TK_InsR_INSR_Y	P06213	INSR	P06213	INSR	Y1185	T1187M	1187	Missense	proximal	2	no	13.813	12.988	EPSD;PhosphoSitePlus	TCGA;COSMIC	10.312	Down-regulation
TK_InsR_INSR_Y	P06213	INSR	P06213	INSR	Y1185	T1181A	1181	Missense	distal	-4	no	13.813	12.553	EPSD;PhosphoSitePlus	TCGA	10.312	Down-regulation
TK_InsR_INSR_Y	P06213	INSR	P06213	INSR	Y1185	R1191Q	1191	Missense	distal	6	no	13.813	13.808	EPSD;PhosphoSitePlus	TCGA;COSMIC	10.312	Down-regulation
TK_InsR_INSR_Y	P06213	INSR	P06213	INSR	Y1189	E1186Q	1186	Missense	distal	-3	no	14.032	13.326	EPSD;PhosphoSitePlus	TCGA;COSMIC	10.312	Down-regulation
TK_InsR_INSR_Y	P06213	INSR	P06213	INSR	Y1189	R1182G	1182	Missense	distal	-7	no	14.032	14.219	EPSD;PhosphoSitePlus	TCGA;COSMIC	10.312	Up-regulation
TK_InsR_INSR_Y	P06213	INSR	P06213	INSR	Y1189	T1187M	1187	Missense	proximal	-2	no	14.032	12.493	EPSD;PhosphoSitePlus	TCGA;COSMIC	10.312	Down-regulation
TK_InsR_INSR_Y	P06213	INSR	P06213	INSR	Y1189	R1191Q	1191	Missense	proximal	2	no	14.032	14.580	EPSD;PhosphoSitePlus	TCGA;COSMIC	10.312	Up-regulation
TK_InsR_INSR_Y	P06213	INSR	P06213	INSR	Y1189	G1193W	1193	Missense	distal	4	no	14.032	12.741	EPSD;PhosphoSitePlus	TCGA	10.312	Down-regulation
TK_InsR_INSR_Y	P06213	INSR	P06213	INSR	Y1190	E1186Q	1186	Missense	distal	-4	no	14.970	14.297	EPSD;PhosphoSitePlus	TCGA;COSMIC	10.312	Down-regulation
TK_InsR_INSR_Y	P06213	INSR	P06213	INSR	Y1190	T1187M	1187	Missense	distal	-3	no	14.970	13.744	EPSD;PhosphoSitePlus	TCGA;COSMIC	10.312	Down-regulation
TK_InsR_INSR_Y	P06213	INSR	P06213	INSR	Y1190	R1191Q	1191	Missense	proximal	1	no	14.970	15.340	EPSD;PhosphoSitePlus	TCGA;COSMIC	10.312	Up-regulation
TK_InsR_INSR_Y	P06213	INSR	P06213	INSR	Y1190	G1193W	1193	Missense	distal	3	no	14.970	14.171	EPSD;PhosphoSitePlus	TCGA	10.312	Down-regulation
TK_InsR_INSR_Y	P06213	INSR	P06213	INSR	Y1355	E1356K	1356	Missense	proximal	1	no	11.720	10.051	EPSD;PhosphoSitePlus	TCGA;COSMIC	10.312	Loss
TK_InsR_INSR_Y	P06213	INSR	P06213	INSR	Y1355	Y1361D	1361	Missense	distal	6	no	11.720	11.950	EPSD;PhosphoSitePlus	TCGA;COSMIC	10.312	Up-regulation
TK_InsR_INSR_Y	P27986	PIK3R1	P06213	INSR	Y504	E510V	510	Missense	distal	6	no	14.060	13.768	EPSD	TCGA;COSMIC	10.312	Down-regulation
TK_InsR_INSR_Y	P27986	PIK3R1	P06213	INSR	Y688	P684S	684	Missense	distal	-4	no	9.032	11.166	EPSD	TCGA;COSMIC;GDSC;CCLE	10.312	Gain
TK_InsR_INSR_Y	Q13480	GAB1	P06213	INSR	Y83	I84V	84	Missense	proximal	1	no	9.277	10.389	EPSD	TCGA;ICGC;COSMIC	10.312	Gain
TK_InsR_INSR_Y	Q13480	GAB1	P06213	INSR	Y285	T289N	289	Missense	distal	4	no	13.084	13.089	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	10.312	Up-regulation
TK_InsR_INSR_Y	Q13480	GAB1	P06213	INSR	Y373	D370N	370	Missense	distal	-3	no	11.973	10.496	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	10.312	Down-regulation
TK_InsR_INSR_Y	Q13480	GAB1	P06213	INSR	Y373	S367L	367	Missense	distal	-6	no	11.973	12.008	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	10.312	Up-regulation
TK_InsR_INSR_Y	Q13480	GAB1	P06213	INSR	Y406	R410Q	410	Missense	distal	4	no	10.487	10.806	EPSD	TCGA;ICGC;COSMIC	10.312	Up-regulation
TK_InsR_INSR_Y	Q13480	GAB1	P06213	INSR	Y447	P452L	452	Missense	distal	5	no	17.503	17.725	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	10.312	Up-regulation
TK_InsR_INSR_Y	Q13480	GAB1	P06213	INSR	Y447	M450K	450	Missense	distal	3	no	17.503	17.202	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	10.312	Down-regulation
TK_InsR_INSR_Y	Q13017	ARHGAP5	P06213	INSR	Y306	P301S	301	Missense	distal	-5	no	13.779	15.020	PhosphoSitePlus	TCGA;ICGC;COSMIC	10.312	Up-regulation
TK_InsR_INSR_Y	Q13017	ARHGAP5	P06213	INSR	Y306	H300Y	300	Missense	distal	-6	no	13.779	13.778	PhosphoSitePlus	TCGA;ICGC;COSMIC	10.312	Down-regulation
TK_InsR_INSR_Y	Q13017	ARHGAP5	P06213	INSR	Y306	P301H	301	Missense	distal	-5	no	13.779	13.508	PhosphoSitePlus	TCGA;ICGC;COSMIC	10.312	Down-regulation
TK_InsR_INSR_Y	Q13017	ARHGAP5	P06213	INSR	Y949	L950V	950	Missense	proximal	1	no	8.474	10.446	EPSD	TCGA;ICGC	10.312	Gain
TK_InsR_INSR_Y	Q13017	ARHGAP5	P06213	INSR	Y1109	D1106H	1106	Missense	distal	-3	no	11.160	7.701	EPSD	TCGA;ICGC;COSMIC	10.312	Loss
TK_InsR_INSR_Y	Q99704	DOK1	P06213	INSR	Y146	E139D	139	Missense	distal	-7	no	10.363	10.557	EPSD	TCGA;ICGC;COSMIC	10.312	Up-regulation
TK_InsR_INSR_Y	Q99704	DOK1	P06213	INSR	Y315	S310F	310	Missense	distal	-5	no	14.208	12.051	EPSD	TCGA;COSMIC	10.312	Down-regulation
TK_InsR_INSR_Y	Q99704	DOK1	P06213	INSR	Y315	D317N	317	Missense	proximal	2	no	14.208	13.347	EPSD	TCGA;COSMIC	10.312	Down-regulation
TK_InsR_INSR_Y	Q99704	DOK1	P06213	INSR	Y315	P318S	318	Missense	distal	3	no	14.208	14.969	EPSD	TCGA;ICGC	10.312	Up-regulation
TK_InsR_INSR_Y	Q99704	DOK1	P06213	INSR	Y362	P365H	365	Missense	distal	3	no	14.400	14.535	EPSD;PhosphoSitePlus	TCGA;COSMIC	10.312	Up-regulation
TK_InsR_INSR_Y	Q99704	DOK1	P06213	INSR	Y398	P404L	404	Missense	distal	6	no	11.865	11.792	PhosphoSitePlus;EPSD	TCGA;COSMIC	10.312	Down-regulation
TK_InsR_INSR_Y	P60484	PTEN	P06213	INSR	Y27	L25V	25	Missense	proximal	-2	no	9.201	11.961	EPSD;PhosphoSitePlus	TCGA;GDSC;CCLE	10.312	Gain
TK_InsR_INSR_Y	P60484	PTEN	P06213	INSR	Y27	Y29S	29	Missense	proximal	2	no	9.201	11.462	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	10.312	Gain
TK_InsR_INSR_Y	P60484	PTEN	P06213	INSR	Y27	I28S	28	Missense	proximal	1	no	9.201	10.689	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	10.312	Gain
TK_InsR_INSR_Y	P60484	PTEN	P06213	INSR	Y27	I28T	28	Missense	proximal	1	no	9.201	10.610	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	10.312	Gain
TK_InsR_INSR_Y	P60484	PTEN	P06213	INSR	Y174	Q171E	171	Missense	distal	-3	no	9.762	10.467	PhosphoSitePlus;EPSD	TCGA;ICGC;COSMIC	10.312	Gain
TK_InsR_INSR_Y	P60484	PTEN	P06213	INSR	Y178	Y177D	177	Missense	proximal	-1	no	6.368	10.895	EPSD	TCGA;ICGC;COSMIC	10.312	Gain
TK_InsR_INSR_Y	P60484	PTEN	P06213	INSR	Y315	D312N	312	Missense	distal	-3	no	12.360	10.883	EPSD	TCGA;ICGC;COSMIC	10.312	Down-regulation
TK_InsR_INSR_Y	P60484	PTEN	P06213	INSR	Y315	K322E	322	Missense	distal	7	no	12.360	12.363	EPSD	TCGA;ICGC;COSMIC	10.312	Up-regulation
TK_InsR_INSR_Y	P60484	PTEN	P06213	INSR	Y315	D310G	310	Missense	distal	-5	no	12.360	11.327	EPSD	TCGA;ICGC;COSMIC;GDSC;CCLE	10.312	Down-regulation
TK_InsR_INSR_Y	P60484	PTEN	P06213	INSR	Y315	R308C	308	Missense	distal	-7	no	12.360	12.156	EPSD	TCGA;ICGC;COSMIC	10.312	Down-regulation
TK_InsR_INSR_Y	P60484	PTEN	P06213	INSR	Y315	L320S	320	Missense	distal	5	no	12.360	11.208	EPSD	TCGA;ICGC;COSMIC	10.312	Down-regulation
TK_InsR_INSR_Y	P60484	PTEN	P06213	INSR	Y377	E373K	373	Missense	distal	-4	no	12.774	11.574	EPSD	TCGA;ICGC	10.312	Down-regulation
TK_InsR_INSR_Y	P60484	PTEN	P06213	INSR	Y377	N372D	372	Missense	distal	-5	no	12.774	13.349	EPSD	TCGA;ICGC;COSMIC	10.312	Up-regulation
TK_InsR_INSR_Y	P60484	PTEN	P06213	INSR	Y379	E373K	373	Missense	distal	-6	no	12.398	12.404	EPSD	TCGA;ICGC	10.312	Up-regulation
TK_InsR_INSR_Y	P60484	PTEN	P06213	INSR	Y379	N372D	372	Missense	distal	-7	no	12.398	12.978	EPSD	TCGA;ICGC;COSMIC	10.312	Up-regulation
TK_InsR_INSR_Y	Q92569	PIK3R3	P06213	INSR	Y341	A337G	337	Missense	distal	-4	no	15.740	16.254	PhosphoSitePlus	TCGA	10.312	Up-regulation
TK_InsR_INSR_Y	Q92569	PIK3R3	P06213	INSR	Y341	E339K	339	Missense	proximal	-2	no	15.740	12.464	PhosphoSitePlus	TCGA;COSMIC	10.312	Down-regulation
TK_InsR_INSR_Y	Q92569	PIK3R3	P06213	INSR	Y341	A337T	337	Missense	distal	-4	no	15.740	17.001	PhosphoSitePlus	TCGA	10.312	Up-regulation
TK_InsR_INSR_Y	P29350	PTPN6	P06213	INSR	Y301	I307M	307	Missense	distal	6	no	10.582	10.663	EPSD	TCGA;COSMIC	10.312	Up-regulation
TK_InsR_INSR_Y	P29350	PTPN6	P06213	INSR	Y301	A304T	304	Missense	distal	3	no	10.582	11.000	EPSD	TCGA;COSMIC	10.312	Up-regulation
TK_InsR_INSR_Y	P29350	PTPN6	P06213	INSR	Y564	E561Q	561	Missense	distal	-3	no	12.156	11.451	EPSD	TCGA;ICGC;COSMIC	10.312	Down-regulation
TK_InsR_INSR_Y	P35232	PHB	P06213	INSR	Y114	R117C	117	Missense	distal	3	no	16.235	16.238	PhosphoSitePlus	TCGA;ICGC;COSMIC	10.312	Up-regulation
TK_InsR_INSR_Y	P35232	PHB	P06213	INSR	Y114	E116A	116	Missense	proximal	2	no	16.235	14.784	PhosphoSitePlus	TCGA;ICGC;COSMIC	10.312	Down-regulation
TK_InsR_INSR_Y	P35232	PHB	P06213	INSR	Y114	P120S	120	Missense	distal	6	no	16.235	16.575	PhosphoSitePlus	TCGA;ICGC	10.312	Up-regulation
TK_InsR_INSR_Y	Q9P219	CCDC88C	P06213	INSR	Y1699	D1698E	1698	Missense	proximal	-1	no	11.100	9.457	EPSD	TCGA;COSMIC	10.312	Loss
TK_InsR_INSR_Y	P25963	NFKBIA	P06213	INSR	Y42	E41K	41	Missense	proximal	-1	no	14.355	12.113	PhosphoSitePlus	TCGA;ICGC	10.312	Down-regulation
TK_InsR_INSR_Y	P25963	NFKBIA	P06213	INSR	Y42	Y42C	42	Missense	central	0	yes	14.355	0.000	PhosphoSitePlus	TCGA;ICGC;COSMIC	10.312	Loss
TK_InsR_INSR_Y	P25963	NFKBIA	P06213	INSR	Y305	D307N	307	Missense	proximal	2	no	12.150	11.289	EPSD	TCGA;COSMIC	10.312	Down-regulation
TK_InsR_INSR_Y	P25963	NFKBIA	P06213	INSR	Y305	E302Q	302	Missense	distal	-3	no	12.150	11.444	EPSD	TCGA;COSMIC	10.312	Down-regulation
TK_InsR_INSR_Y	P25963	NFKBIA	P06213	INSR	Y305	Y305C	305	Missense	central	0	yes	12.150	0.000	EPSD	TCGA;COSMIC	10.312	Loss
STE_STE-Unique_MAP3K8_ST	P35241	RDX	P41279	MAP3K8	S249	I245F	245	Missense	distal	-4	no	22.416	22.607	EPSD	TCGA;COSMIC	13.250	Up-regulation
STE_STE-Unique_MAP3K8_ST	P35241	RDX	P41279	MAP3K8	S249	R246K	246	Missense	distal	-3	no	22.416	16.545	EPSD	TCGA;COSMIC	13.250	Down-regulation
STE_STE-Unique_MAP3K8_ST	P35241	RDX	P41279	MAP3K8	S249	K254T	254	Missense	distal	5	no	22.416	23.012	EPSD	TCGA;ICGC;COSMIC	13.250	Up-regulation
STE_STE-Unique_MAP3K8_ST	P35241	RDX	P41279	MAP3K8	S249	F255Y	255	Missense	distal	6	no	22.416	22.027	EPSD	TCGA;COSMIC	13.250	Down-regulation
STE_STE-Unique_MAP3K8_ST	P35241	RDX	P41279	MAP3K8	T518	E517D	517	Missense	proximal	-1	no	19.290	22.112	EPSD	TCGA;ICGC	13.250	Up-regulation
STE_STE-Unique_MAP3K8_ST	P35241	RDX	P41279	MAP3K8	T542	K543N	543	Missense	proximal	1	no	14.063	12.825	EPSD	TCGA	13.250	Loss
STE_STE-Unique_MAP3K8_ST	P35241	RDX	P41279	MAP3K8	T564	R569Q	569	Missense	distal	5	no	27.578	28.115	PhosphoSitePlus	TCGA;ICGC	13.250	Up-regulation
STE_STE-Unique_MAP3K8_ST	P35241	RDX	P41279	MAP3K8	T564	D560Y	560	Missense	distal	-4	no	27.578	28.360	PhosphoSitePlus	TCGA;COSMIC	13.250	Up-regulation
STE_STE-Unique_MAP3K8_ST	P35241	RDX	P41279	MAP3K8	T564	R566Q	566	Missense	proximal	2	no	27.578	27.131	PhosphoSitePlus	TCGA;COSMIC	13.250	Down-regulation
STE_STE-Unique_MAP3K8_ST	P35241	RDX	P41279	MAP3K8	T564	A557T	557	Missense	distal	-7	no	27.578	27.674	PhosphoSitePlus	TCGA;ICGC;COSMIC	13.250	Up-regulation
STE_STE-Unique_MAP3K8_ST	P46734	MAP2K3	P41279	MAP3K8	S218	M223I	223	Missense	distal	5	no	35.996	36.279	PhosphoSitePlus	TCGA;COSMIC	13.250	Up-regulation
STE_STE-Unique_MAP3K8_ST	P46734	MAP2K3	P41279	MAP3K8	S218	A225V	225	Missense	distal	7	no	35.996	35.675	PhosphoSitePlus	TCGA;COSMIC	13.250	Down-regulation
STE_STE-Unique_MAP3K8_ST	P46734	MAP2K3	P41279	MAP3K8	S218	S218Y	218	Missense	central	0	yes	35.996	0.000	PhosphoSitePlus	TCGA;CCLE	13.250	Loss
STE_STE-Unique_MAP3K8_ST	P46734	MAP2K3	P41279	MAP3K8	S218	S212N	212	Missense	distal	-6	no	35.996	35.600	PhosphoSitePlus	TCGA;COSMIC	13.250	Down-regulation
STE_STE-Unique_MAP3K8_ST	P46734	MAP2K3	P41279	MAP3K8	T222	M223I	223	Missense	proximal	1	no	14.272	11.999	EPSD	TCGA;COSMIC	13.250	Loss
STE_STE-Unique_MAP3K8_ST	P46734	MAP2K3	P41279	MAP3K8	T222	C227F	227	Missense	distal	5	no	14.272	14.202	EPSD	TCGA;COSMIC	13.250	Down-regulation
STE_STE-Unique_MAP3K8_ST	P46734	MAP2K3	P41279	MAP3K8	T222	P229S	229	Missense	distal	7	no	14.272	15.267	EPSD	TCGA;COSMIC	13.250	Up-regulation
STE_STE-Unique_MAP3K8_ST	P46734	MAP2K3	P41279	MAP3K8	T222	A225V	225	Missense	distal	3	no	14.272	16.289	EPSD	TCGA;COSMIC	13.250	Up-regulation
STE_STE-Unique_MAP3K8_ST	P46734	MAP2K3	P41279	MAP3K8	T222	S218Y	218	Missense	distal	-4	no	14.272	15.025	EPSD	TCGA;CCLE	13.250	Up-regulation
STE_STE-Unique_MAP3K8_ST	Q14653	IRF3	P41279	MAP3K8	T32	R33C	33	Missense	proximal	1	no	13.813	9.323	EPSD	TCGA;ICGC;COSMIC	13.250	Loss
STE_STE-Unique_MAP3K8_ST	Q14653	IRF3	P41279	MAP3K8	T135	D138G	138	Missense	distal	3	no	14.075	15.650	EPSD	TCGA;COSMIC	13.250	Up-regulation
STE_STE-Unique_MAP3K8_ST	Q14653	IRF3	P41279	MAP3K8	T135	G129E	129	Missense	distal	-6	no	14.075	14.060	EPSD	TCGA;COSMIC	13.250	Down-regulation
STE_STE-Unique_MAP3K8_ST	Q14653	IRF3	P41279	MAP3K8	S175	P170S	170	Missense	distal	-5	no	15.760	15.874	EPSD;PhosphoSitePlus	TCGA;COSMIC;CCLE	13.250	Up-regulation
STE_STE-Unique_MAP3K8_ST	Q14653	IRF3	P41279	MAP3K8	S259	T253K	253	Missense	distal	-6	no	14.053	13.148	EPSD	TCGA;COSMIC	13.250	Loss
STE_STE-Unique_MAP3K8_ST	Q14653	IRF3	P41279	MAP3K8	S259	V261A	261	Missense	proximal	2	no	14.053	13.749	EPSD	TCGA;COSMIC	13.250	Down-regulation
STE_STE-Unique_MAP3K8_ST	P15311	EZR	P41279	MAP3K8	S249	S249F	249	Missense	central	0	yes	22.102	0.000	EPSD	TCGA;ICGC;COSMIC	13.250	Loss
STE_STE-Unique_MAP3K8_ST	P15311	EZR	P41279	MAP3K8	T533	L538V	538	Missense	distal	5	no	20.836	20.900	EPSD	TCGA;ICGC;COSMIC	13.250	Up-regulation
STE_STE-Unique_MAP3K8_ST	P15311	EZR	P41279	MAP3K8	T533	V527M	527	Missense	distal	-6	no	20.836	20.969	EPSD	TCGA;ICGC;COSMIC	13.250	Up-regulation
STE_STE-Unique_MAP3K8_ST	P15311	EZR	P41279	MAP3K8	S535	L538V	538	Missense	distal	3	no	12.923	15.995	EPSD	TCGA;ICGC;COSMIC	13.250	Gain
STE_STE-Unique_MAP3K8_ST	P15311	EZR	P41279	MAP3K8	S536	A541V	541	Missense	distal	5	no	16.296	15.804	EPSD	TCGA;ICGC;COSMIC	13.250	Down-regulation
STE_STE-Unique_MAP3K8_ST	P15311	EZR	P41279	MAP3K8	S539	L538V	538	Missense	proximal	-1	no	16.550	17.125	EPSD	TCGA;ICGC;COSMIC	13.250	Up-regulation
STE_STE-Unique_MAP3K8_ST	P15311	EZR	P41279	MAP3K8	S539	A541V	541	Missense	proximal	2	no	16.550	16.853	EPSD	TCGA;ICGC;COSMIC	13.250	Up-regulation
STE_STE-Unique_MAP3K8_ST	P15311	EZR	P41279	MAP3K8	T567	R562Q	562	Missense	distal	-5	no	30.912	30.821	PhosphoSitePlus	TCGA;ICGC	13.250	Down-regulation
STE_STE-Unique_MAP3K8_ST	P15311	EZR	P41279	MAP3K8	T567	R569Q	569	Missense	proximal	2	no	30.912	30.465	PhosphoSitePlus	TCGA;ICGC;COSMIC	13.250	Down-regulation
STE_STE-Unique_MAP3K8_ST	P00519	ABL1	P41279	MAP3K8	S620	S620G	620	Missense	central	0	yes	13.284	0.000	EPSD	TCGA;COSMIC	13.250	Loss
STE_STE-Unique_MAP3K8_ST	P00519	ABL1	P41279	MAP3K8	S620	S620R	620	Missense	central	0	yes	13.284	0.000	EPSD	TCGA;COSMIC	13.250	Loss
STE_STE-Unique_MAP3K8_ST	P16220	CREB1	P41279	MAP3K8	S98	S103A	103	Missense	distal	5	no	18.463	18.831	EPSD	TCGA;COSMIC	13.250	Up-regulation
STE_STE-Unique_MAP3K8_ST	P16220	CREB1	P41279	MAP3K8	T104	S103A	103	Missense	proximal	-1	no	19.334	18.251	EPSD	TCGA;COSMIC	13.250	Down-regulation
STE_STE-Unique_MAP3K8_ST	P16220	CREB1	P41279	MAP3K8	S111	D116G	116	Missense	distal	5	no	13.478	13.801	EPSD	TCGA;COSMIC	13.250	Up-regulation
STE_STE-Unique_MAP3K8_ST	P16220	CREB1	P41279	MAP3K8	S111	Q112H	112	Missense	proximal	1	no	13.478	12.228	EPSD	TCGA;COSMIC	13.250	Loss
STE_STE-Unique_MAP3K8_ST	P16220	CREB1	P41279	MAP3K8	S121	D116G	116	Missense	distal	-5	no	17.077	17.005	EPSD	TCGA;COSMIC	13.250	Down-regulation
STE_STE-Unique_MAP3K8_ST	P16220	CREB1	P41279	MAP3K8	S121	L128I	128	Missense	distal	7	no	17.077	17.729	EPSD	TCGA;COSMIC	13.250	Up-regulation
STE_STE-Unique_MAP3K8_ST	P16220	CREB1	P41279	MAP3K8	S133	L128I	128	Missense	distal	-5	no	36.386	36.413	PhosphoSitePlus	TCGA;COSMIC	13.250	Up-regulation
STE_STE-Unique_MAP3K8_ST	Q04637	EIF4G1	P41279	MAP3K8	S1164	G1158D	1158	Missense	distal	-6	no	15.969	16.206	EPSD	TCGA;COSMIC	13.250	Up-regulation
STE_STE-Unique_MAP3K8_ST	Q04637	EIF4G1	P41279	MAP3K8	T1179	R1173Q	1173	Missense	distal	-6	no	26.900	26.581	EPSD	TCGA	13.250	Down-regulation
STE_STE-Unique_MAP3K8_ST	P52564	MAP2K6	P41279	MAP3K8	S207	K210R	210	Missense	distal	3	no	36.275	38.715	PhosphoSitePlus	TCGA;COSMIC	13.250	Up-regulation
STE_STE-Unique_MAP3K8_ST	P52564	MAP2K6	P41279	MAP3K8	S207	S207Y	207	Missense	central	0	yes	36.275	0.000	PhosphoSitePlus	TCGA	13.250	Loss
STE_STE-Unique_MAP3K8_ST	P52564	MAP2K6	P41279	MAP3K8	T211	K210R	210	Missense	proximal	-1	no	12.561	14.229	EPSD	TCGA;COSMIC	13.250	Gain
STE_STE-Unique_MAP3K8_ST	P52564	MAP2K6	P41279	MAP3K8	T211	S207Y	207	Missense	distal	-4	no	12.561	13.314	EPSD	TCGA	13.250	Gain
STE_STE-Unique_MAP3K8_ST	Q13541	EIF4EBP1	P41279	MAP3K8	T70	L75M	75	Missense	distal	5	no	22.215	22.131	PhosphoSitePlus	TCGA;ICGC	13.250	Down-regulation
STE_STE-Unique_MAP3K8_ST	P53350	PLK1	P41279	MAP3K8	S137	R134H	134	Missense	distal	-3	no	24.840	13.930	EPSD;PhosphoSitePlus	TCGA;ICGC	13.250	Down-regulation
STE_STE-Unique_MAP3K8_ST	P53350	PLK1	P41279	MAP3K8	T210	G213V	213	Missense	distal	3	no	36.192	34.455	PhosphoSitePlus;EPSD	TCGA;ICGC	13.250	Down-regulation
STE_STE-Unique_MAP3K8_ST	P53350	PLK1	P41279	MAP3K8	T210	K208E	208	Missense	proximal	-2	no	36.192	35.866	PhosphoSitePlus;EPSD	TCGA;ICGC;COSMIC	13.250	Down-regulation
STE_STE-Unique_MAP3K8_ST	P53350	PLK1	P41279	MAP3K8	T210	D204G	204	Missense	distal	-6	no	36.192	35.955	PhosphoSitePlus;EPSD	TCGA;ICGC;COSMIC	13.250	Down-regulation
STE_STE-Unique_MAP3K8_ST	P53350	PLK1	P41279	MAP3K8	S578	E575K	575	Missense	distal	-3	no	10.127	17.860	EPSD	TCGA;ICGC;COSMIC	13.250	Gain
STE_STE-Unique_MAP3K8_ST	Q02750	MAP2K1	P41279	MAP3K8	S200	E203K	203	Missense	distal	3	no	12.644	13.611	EPSD	TCGA;ICGC;COSMIC;GDSC	13.250	Gain
STE_STE-Unique_MAP3K8_ST	Q02750	MAP2K1	P41279	MAP3K8	S218	V224M	224	Missense	distal	6	no	35.306	35.155	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	13.250	Down-regulation
STE_STE-Unique_MAP3K8_ST	Q02750	MAP2K1	P41279	MAP3K8	S222	V224M	224	Missense	proximal	2	no	29.794	29.921	PhosphoSitePlus;EPSD	TCGA;ICGC;COSMIC	13.250	Up-regulation
STE_STE-Unique_MAP3K8_ST	Q02750	MAP2K1	P41279	MAP3K8	S222	R227K	227	Missense	distal	5	no	29.794	30.242	PhosphoSitePlus;EPSD	TCGA;ICGC;COSMIC	13.250	Up-regulation
STE_STE-Unique_MAP3K8_ST	Q02750	MAP2K1	P41279	MAP3K8	S231	L235H	235	Missense	distal	4	no	15.435	17.153	EPSD	TCGA;ICGC;COSMIC	13.250	Up-regulation
STE_STE-Unique_MAP3K8_ST	Q02750	MAP2K1	P41279	MAP3K8	S231	S231L	231	Missense	central	0	yes	15.435	0.000	EPSD	TCGA;ICGC;COSMIC	13.250	Loss
STE_STE-Unique_MAP3K8_ST	Q02750	MAP2K1	P41279	MAP3K8	S231	V224M	224	Missense	distal	-7	no	15.435	15.501	EPSD	TCGA;ICGC;COSMIC	13.250	Up-regulation
STE_STE-Unique_MAP3K8_ST	Q02750	MAP2K1	P41279	MAP3K8	S231	R227K	227	Missense	distal	-4	no	15.435	15.794	EPSD	TCGA;ICGC;COSMIC	13.250	Up-regulation
STE_STE-Unique_MAP3K8_ST	Q15418	RPS6KA1	P41279	MAP3K8	T643	G639S	639	Missense	distal	-4	no	18.329	18.033	EPSD	TCGA;ICGC;COSMIC	13.250	Down-regulation
STE_STE-Unique_MAP3K8_ST	P26038	MSN	P41279	MAP3K8	S249	D252H	252	Missense	distal	3	no	23.574	23.419	EPSD	TCGA;ICGC;COSMIC	13.250	Down-regulation
STE_STE-Unique_MAP3K8_ST	P26038	MSN	P41279	MAP3K8	S504	R503C	503	Missense	proximal	-1	no	21.992	19.214	EPSD	TCGA;ICGC;COSMIC	13.250	Down-regulation
STE_STE-Unique_MAP3K8_ST	P26038	MSN	P41279	MAP3K8	S504	R508C	508	Missense	distal	4	no	21.992	22.441	EPSD	TCGA;ICGC;COSMIC	13.250	Up-regulation
STE_STE-Unique_MAP3K8_ST	P26038	MSN	P41279	MAP3K8	S504	R503H	503	Missense	proximal	-1	no	21.992	18.506	EPSD	TCGA;ICGC;COSMIC	13.250	Down-regulation
STE_STE-Unique_MAP3K8_ST	P26038	MSN	P41279	MAP3K8	S504	E505K	505	Missense	proximal	1	no	21.992	25.091	EPSD	TCGA;ICGC;COSMIC	13.250	Up-regulation
STE_STE-Unique_MAP3K8_ST	P26038	MSN	P41279	MAP3K8	T509	R503C	503	Missense	distal	-6	no	15.995	15.628	EPSD	TCGA;ICGC;COSMIC	13.250	Down-regulation
STE_STE-Unique_MAP3K8_ST	P26038	MSN	P41279	MAP3K8	T509	R508C	508	Missense	proximal	-1	no	15.995	13.217	EPSD	TCGA;ICGC;COSMIC	13.250	Loss
STE_STE-Unique_MAP3K8_ST	P26038	MSN	P41279	MAP3K8	T509	R503H	503	Missense	distal	-6	no	15.995	15.530	EPSD	TCGA;ICGC;COSMIC	13.250	Down-regulation
STE_STE-Unique_MAP3K8_ST	P26038	MSN	P41279	MAP3K8	T509	E505K	505	Missense	distal	-4	no	15.995	16.236	EPSD	TCGA;ICGC;COSMIC	13.250	Up-regulation
STE_STE-Unique_MAP3K8_ST	P26038	MSN	P41279	MAP3K8	S536	D534Y	534	Missense	proximal	-2	no	13.986	13.635	EPSD	TCGA;ICGC;COSMIC	13.250	Down-regulation
STE_STE-Unique_MAP3K8_ST	P26038	MSN	P41279	MAP3K8	S536	A532D	532	Missense	distal	-4	no	13.986	13.363	EPSD	TCGA;ICGC;COSMIC	13.250	Down-regulation
STE_STE-Unique_MAP3K8_ST	P26038	MSN	P41279	MAP3K8	T558	R560C	560	Missense	proximal	2	no	29.457	28.928	PhosphoSitePlus	TCGA;ICGC;COSMIC	13.250	Down-regulation
STE_STE-Unique_MAP3K8_ST	P26038	MSN	P41279	MAP3K8	T558	Q561H	561	Missense	distal	3	no	29.457	27.286	PhosphoSitePlus	TCGA;ICGC;COSMIC	13.250	Down-regulation
STE_STE-Unique_MAP3K8_ST	P26038	MSN	P41279	MAP3K8	T558	K557N	557	Missense	proximal	-1	no	29.457	30.180	PhosphoSitePlus	TCGA;ICGC	13.250	Up-regulation
STE_STE-Unique_MAP3K8_ST	P26038	MSN	P41279	MAP3K8	T558	R553Q	553	Missense	distal	-5	no	29.457	29.366	PhosphoSitePlus	TCGA;ICGC	13.250	Down-regulation
STE_STE-Unique_MAP3K8_ST	P06493	CDK1	P41279	MAP3K8	S53	E57V	57	Missense	distal	4	no	16.506	16.548	EPSD	TCGA;ICGC;COSMIC	13.250	Up-regulation
STE_STE-Unique_MAP3K8_ST	P06493	CDK1	P41279	MAP3K8	S53	R59C	59	Missense	distal	6	no	16.506	15.235	EPSD	TCGA;ICGC;COSMIC;GDSC	13.250	Down-regulation
STE_STE-Unique_MAP3K8_ST	P06493	CDK1	P41279	MAP3K8	S53	R50W	50	Missense	distal	-3	no	16.506	4.749	EPSD	TCGA;ICGC;COSMIC	13.250	Loss
STE_STE-Unique_MAP3K8_ST	P06493	CDK1	P41279	MAP3K8	S248	L249P	249	Missense	proximal	1	no	14.692	11.682	EPSD	TCGA;ICGC;COSMIC	13.250	Loss
STE_STE-Unique_MAP3K8_ST	P06493	CDK1	P41279	MAP3K8	S248	P242S	242	Missense	distal	-6	no	14.692	16.077	EPSD	TCGA;ICGC;COSMIC	13.250	Up-regulation
STE_STE-Unique_MAP3K8_ST	P06493	CDK1	P41279	MAP3K8	S248	S251F	251	Missense	distal	3	no	14.692	12.060	EPSD	TCGA;ICGC;COSMIC	13.250	Loss
STE_STE-Unique_MAP3K8_ST	P06493	CDK1	P41279	MAP3K8	S248	V253A	253	Missense	distal	5	no	14.692	15.184	EPSD	TCGA;ICGC	13.250	Up-regulation
STE_STE-Unique_MAP3K8_ST	P36507	MAP2K2	P41279	MAP3K8	S204	E207K	207	Missense	distal	3	no	12.366	13.332	EPSD	TCGA;ICGC;COSMIC	13.250	Gain
STE_STE-Unique_MAP3K8_ST	P36507	MAP2K2	P41279	MAP3K8	S222	V228M	228	Missense	distal	6	no	34.924	34.773	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	13.250	Down-regulation
STE_STE-Unique_MAP3K8_ST	P36507	MAP2K2	P41279	MAP3K8	S226	T230M	230	Missense	distal	4	no	29.977	27.832	PhosphoSitePlus;EPSD	TCGA;ICGC;COSMIC	13.250	Down-regulation
STE_STE-Unique_MAP3K8_ST	P36507	MAP2K2	P41279	MAP3K8	S226	V228M	228	Missense	proximal	2	no	29.977	30.104	PhosphoSitePlus;EPSD	TCGA;ICGC;COSMIC	13.250	Up-regulation
STE_STE-Unique_MAP3K8_ST	P36507	MAP2K2	P41279	MAP3K8	S295	H292R	292	Missense	distal	-3	no	2.716	13.626	EPSD	TCGA;ICGC;COSMIC	13.250	Gain
STE_STE-Unique_MAP3K8_ST	O14757	CHEK1	P41279	MAP3K8	T153	R160H	160	Missense	distal	7	no	14.179	14.058	EPSD	TCGA;ICGC;COSMIC	13.250	Down-regulation
STE_STE-Unique_MAP3K8_ST	O14757	CHEK1	P41279	MAP3K8	T153	R160C	160	Missense	distal	7	no	14.179	14.023	EPSD	TCGA;ICGC;COSMIC	13.250	Down-regulation
STE_STE-Unique_MAP3K8_ST	O14757	CHEK1	P41279	MAP3K8	T153	R156W	156	Missense	distal	3	no	14.179	9.057	EPSD	TCGA;ICGC;COSMIC	13.250	Loss
STE_STE-Unique_MAP3K8_ST	O14757	CHEK1	P41279	MAP3K8	T153	R156Q	156	Missense	distal	3	no	14.179	11.535	EPSD	TCGA;ICGC	13.250	Loss
STE_STE-Unique_MAP3K8_ST	O14757	CHEK1	P41279	MAP3K8	S280	G281D	281	Missense	proximal	1	no	10.488	15.380	EPSD	TCGA;ICGC;COSMIC	13.250	Gain
STE_STE-Unique_MAP3K8_ST	O14757	CHEK1	P41279	MAP3K8	S286	G289V	289	Missense	distal	3	no	16.636	14.899	EPSD	TCGA;ICGC;COSMIC	13.250	Down-regulation
STE_STE-Unique_MAP3K8_ST	O14757	CHEK1	P41279	MAP3K8	S286	G281D	281	Missense	distal	-5	no	16.636	16.708	EPSD	TCGA;ICGC;COSMIC	13.250	Up-regulation
STE_STE-Unique_MAP3K8_ST	O14757	CHEK1	P41279	MAP3K8	S286	T279I	279	Missense	distal	-7	no	16.636	16.776	EPSD	TCGA;ICGC;COSMIC	13.250	Up-regulation
STE_STE-Unique_MAP3K8_ST	O14757	CHEK1	P41279	MAP3K8	S286	S284L	284	Missense	proximal	-2	no	16.636	16.264	EPSD	TCGA;ICGC;COSMIC	13.250	Down-regulation
STE_STE-Unique_MAP3K8_ST	O14757	CHEK1	P41279	MAP3K8	S286	S288R	288	Missense	proximal	2	no	16.636	17.023	EPSD	TCGA;ICGC;COSMIC	13.250	Up-regulation
STE_STE-Unique_MAP3K8_ST	O14757	CHEK1	P41279	MAP3K8	S301	Q295E	295	Missense	distal	-6	no	14.872	15.042	EPSD	TCGA;ICGC;COSMIC	13.250	Up-regulation
STE_STE-Unique_MAP3K8_ST	O14757	CHEK1	P41279	MAP3K8	S301	S296F	296	Missense	distal	-5	no	14.872	14.763	EPSD	TCGA;ICGC;COSMIC	13.250	Down-regulation
STE_STE-Unique_MAP3K8_ST	O14757	CHEK1	P41279	MAP3K8	S301	N297T	297	Missense	distal	-4	no	14.872	15.404	EPSD	TCGA;ICGC	13.250	Up-regulation
STE_STE-Unique_MAP3K8_ST	O14757	CHEK1	P41279	MAP3K8	S307	E309K	309	Missense	proximal	2	no	18.590	18.785	EPSD	TCGA;COSMIC	13.250	Up-regulation
STE_STE-Unique_MAP3K8_ST	O14757	CHEK1	P41279	MAP3K8	T330	G324C	324	Missense	distal	-6	no	14.654	14.420	EPSD	TCGA;ICGC;COSMIC	13.250	Down-regulation
STE_STE-Unique_MAP3K8_ST	O14757	CHEK1	P41279	MAP3K8	T330	D336N	336	Missense	distal	6	no	14.654	14.108	EPSD	TCGA;ICGC;COSMIC	13.250	Down-regulation
STE_STE-Unique_MAP3K8_ST	O14757	CHEK1	P41279	MAP3K8	T330	K337R	337	Missense	distal	7	no	14.654	14.879	EPSD	TCGA;ICGC;COSMIC	13.250	Up-regulation
STE_STE-Unique_MAP3K8_ST	O14757	CHEK1	P41279	MAP3K8	S345	V339I	339	Missense	distal	-6	no	22.388	22.905	PhosphoSitePlus	TCGA;ICGC;COSMIC	13.250	Up-regulation
STE_STE-Unique_MAP3K8_ST	O14757	CHEK1	P41279	MAP3K8	T417	N421H	421	Missense	distal	4	no	13.786	12.501	EPSD	TCGA	13.250	Loss
STE_STE-Unique_MAP3K8_ST	O14757	CHEK1	P41279	MAP3K8	T417	R419S	419	Missense	proximal	2	no	13.786	13.399	EPSD	TCGA;ICGC;COSMIC;GDSC;CCLE	13.250	Down-regulation
STE_STE-Unique_MAP3K8_ST	O14757	CHEK1	P41279	MAP3K8	T417	S415P	415	Missense	proximal	-2	no	13.786	13.248	EPSD	TCGA;ICGC;COSMIC	13.250	Loss
STE_STE-Unique_MAP3K8_ST	P06748	NPM1	P41279	MAP3K8	S195	I196V	196	Missense	proximal	1	no	31.018	32.233	EPSD	TCGA;ICGC;COSMIC	13.250	Up-regulation
STE_STE-Unique_MAP3K8_ST	P06748	NPM1	P41279	MAP3K8	T199	I196V	196	Missense	distal	-3	no	36.589	37.093	PhosphoSitePlus	TCGA;ICGC;COSMIC	13.250	Up-regulation
STE_STE-Unique_MAP3K8_ST	P06748	NPM1	P41279	MAP3K8	S214	D213N	213	Missense	proximal	-1	no	13.254	13.362	EPSD	TCGA;ICGC;COSMIC	13.250	Up-regulation
STE_STE-Unique_MAP3K8_ST	P06748	NPM1	P41279	MAP3K8	S214	P216S	216	Missense	proximal	2	no	13.254	13.514	EPSD	TCGA;ICGC;COSMIC	13.250	Up-regulation
STE_STE-Unique_MAP3K8_ST	P06748	NPM1	P41279	MAP3K8	S218	P216S	216	Missense	proximal	-2	no	12.826	13.364	EPSD	TCGA;ICGC;COSMIC	13.250	Gain
STE_STE-Unique_MAP3K8_ST	P06748	NPM1	P41279	MAP3K8	T237	K239N	239	Missense	proximal	2	no	17.397	17.437	EPSD	TCGA;ICGC;COSMIC	13.250	Up-regulation
CMGC_MAPK_JNK_MAPK9_ST	P46937	YAP1	P45984	MAPK9	T77	V72I	72	Missense	distal	-5	no	142.599	142.621	EPSD	TCGA;ICGC;COSMIC	140.458	Up-regulation
CMGC_MAPK_JNK_MAPK9_ST	P46937	YAP1	P45984	MAPK9	T110	R106Q	106	Missense	distal	-4	no	143.596	145.027	EPSD	TCGA;ICGC;COSMIC;CCLE	140.458	Up-regulation
CMGC_MAPK_JNK_MAPK9_ST	P46937	YAP1	P45984	MAPK9	T110	S109N	109	Missense	proximal	-1	no	143.596	143.766	EPSD	TCGA;ICGC;COSMIC	140.458	Up-regulation
CMGC_MAPK_JNK_MAPK9_ST	P46937	YAP1	P45984	MAPK9	T119	Q121H	121	Missense	proximal	2	no	163.538	163.676	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	140.458	Up-regulation
CMGC_MAPK_JNK_MAPK9_ST	P46937	YAP1	P45984	MAPK9	T119	R124P	124	Missense	distal	5	no	163.538	163.712	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	140.458	Up-regulation
CMGC_MAPK_JNK_MAPK9_ST	P46937	YAP1	P45984	MAPK9	T119	R124Q	124	Missense	distal	5	no	163.538	163.747	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	140.458	Up-regulation
CMGC_MAPK_JNK_MAPK9_ST	P46937	YAP1	P45984	MAPK9	S128	G135E	135	Missense	distal	7	no	154.316	153.852	EPSD	TCGA;ICGC;COSMIC	140.458	Down-regulation
CMGC_MAPK_JNK_MAPK9_ST	P46937	YAP1	P45984	MAPK9	S128	Q121H	121	Missense	distal	-7	no	154.316	152.644	EPSD	TCGA;ICGC;COSMIC	140.458	Down-regulation
CMGC_MAPK_JNK_MAPK9_ST	P46937	YAP1	P45984	MAPK9	S128	P129S	129	Missense	proximal	1	no	154.316	-126.478	EPSD	TCGA;ICGC;COSMIC	140.458	Loss
CMGC_MAPK_JNK_MAPK9_ST	P46937	YAP1	P45984	MAPK9	S128	R124P	124	Missense	distal	-4	no	154.316	154.436	EPSD	TCGA;ICGC;COSMIC	140.458	Up-regulation
CMGC_MAPK_JNK_MAPK9_ST	P46937	YAP1	P45984	MAPK9	S128	R124Q	124	Missense	distal	-4	no	154.316	155.747	EPSD	TCGA;ICGC;COSMIC	140.458	Up-regulation
CMGC_MAPK_JNK_MAPK9_ST	P46937	YAP1	P45984	MAPK9	S138	G135E	135	Missense	distal	-3	no	156.939	158.396	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	140.458	Up-regulation
CMGC_MAPK_JNK_MAPK9_ST	P46937	YAP1	P45984	MAPK9	S138	S138F	138	Missense	central	0	yes	156.939	0.000	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	140.458	Loss
CMGC_MAPK_JNK_MAPK9_ST	P46937	YAP1	P45984	MAPK9	S138	G140E	140	Missense	proximal	2	no	156.939	156.807	EPSD;PhosphoSitePlus	TCGA;ICGC	140.458	Down-regulation
CMGC_MAPK_JNK_MAPK9_ST	P46937	YAP1	P45984	MAPK9	T143	S138F	138	Missense	distal	-5	no	158.240	158.383	EPSD	TCGA;ICGC;COSMIC	140.458	Up-regulation
CMGC_MAPK_JNK_MAPK9_ST	P46937	YAP1	P45984	MAPK9	T143	G140E	140	Missense	distal	-3	no	158.240	159.698	EPSD	TCGA;ICGC	140.458	Up-regulation
CMGC_MAPK_JNK_MAPK9_ST	P46937	YAP1	P45984	MAPK9	T154	T154A	154	Missense	central	0	yes	159.726	0.000	PhosphoSitePlus;EPSD	TCGA;ICGC;COSMIC	140.458	Loss
CMGC_MAPK_JNK_MAPK9_ST	P46937	YAP1	P45984	MAPK9	T154	Q158H	158	Missense	distal	4	no	159.726	159.997	PhosphoSitePlus;EPSD	TCGA;ICGC;COSMIC	140.458	Up-regulation
CMGC_MAPK_JNK_MAPK9_ST	P46937	YAP1	P45984	MAPK9	S217	A214T	214	Missense	distal	-3	no	152.671	151.424	EPSD	TCGA;ICGC	140.458	Down-regulation
CMGC_MAPK_JNK_MAPK9_ST	P46937	YAP1	P45984	MAPK9	S227	P231H	231	Missense	distal	4	no	147.497	147.768	EPSD	TCGA;ICGC;COSMIC	140.458	Up-regulation
CMGC_MAPK_JNK_MAPK9_ST	P46937	YAP1	P45984	MAPK9	S336	P341A	341	Missense	distal	5	no	143.713	143.783	EPSD	TCGA;ICGC;COSMIC	140.458	Up-regulation
CMGC_MAPK_JNK_MAPK9_ST	P46937	YAP1	P45984	MAPK9	S336	I333N	333	Missense	distal	-3	no	143.713	145.757	EPSD	TCGA;ICGC;COSMIC	140.458	Up-regulation
CMGC_MAPK_JNK_MAPK9_ST	P46937	YAP1	P45984	MAPK9	S336	N339H	339	Missense	distal	3	no	143.713	143.471	EPSD	TCGA;ICGC;COSMIC	140.458	Down-regulation
CMGC_MAPK_JNK_MAPK9_ST	P46937	YAP1	P45984	MAPK9	T337	I333N	333	Missense	distal	-4	no	137.995	141.174	EPSD	TCGA;ICGC;COSMIC	140.458	Gain
CMGC_MAPK_JNK_MAPK9_ST	P46937	YAP1	P45984	MAPK9	S340	P341A	341	Missense	proximal	1	no	159.000	140.357	EPSD	TCGA;ICGC;COSMIC	140.458	Loss
CMGC_MAPK_JNK_MAPK9_ST	P46937	YAP1	P45984	MAPK9	S340	Q344K	344	Missense	distal	4	no	159.000	159.119	EPSD	TCGA;ICGC;COSMIC	140.458	Up-regulation
CMGC_MAPK_JNK_MAPK9_ST	P46937	YAP1	P45984	MAPK9	S340	I333N	333	Missense	distal	-7	no	159.000	161.759	EPSD	TCGA;ICGC;COSMIC	140.458	Up-regulation
CMGC_MAPK_JNK_MAPK9_ST	P46937	YAP1	P45984	MAPK9	S340	N339H	339	Missense	proximal	-1	no	159.000	158.698	EPSD	TCGA;ICGC;COSMIC	140.458	Down-regulation
CMGC_MAPK_JNK_MAPK9_ST	P46937	YAP1	P45984	MAPK9	S367	S366C	366	Missense	proximal	-1	no	157.971	157.926	EPSD	TCGA	140.458	Down-regulation
CMGC_MAPK_JNK_MAPK9_ST	P46937	YAP1	P45984	MAPK9	S367	G369R	369	Missense	proximal	2	no	157.971	157.794	EPSD	TCGA;ICGC	140.458	Down-regulation
CMGC_MAPK_JNK_MAPK9_ST	P46937	YAP1	P45984	MAPK9	S382	D383E	383	Missense	proximal	1	no	141.944	136.458	EPSD	TCGA;ICGC;COSMIC	140.458	Loss
CMGC_MAPK_JNK_MAPK9_ST	P46937	YAP1	P45984	MAPK9	T412	P413Q	413	Missense	proximal	1	no	159.478	139.366	EPSD	TCGA;ICGC;COSMIC	140.458	Loss
CMGC_MAPK_JNK_MAPK9_ST	O43602	DCX	P45984	MAPK9	S28	S28F	28	Missense	central	0	yes	157.902	0.000	EPSD	TCGA;ICGC	140.458	Loss
CMGC_MAPK_JNK_MAPK9_ST	O43602	DCX	P45984	MAPK9	S32	S28F	28	Missense	distal	-4	no	141.959	138.676	EPSD	TCGA;ICGC	140.458	Loss
CMGC_MAPK_JNK_MAPK9_ST	P10636	MAPT	P45984	MAPK9	S46	T52I	52	Missense	distal	6	no	146.918	146.935	EPSD	TCGA;ICGC;COSMIC	140.458	Up-regulation
CMGC_MAPK_JNK_MAPK9_ST	P10636	MAPT	P45984	MAPK9	S46	P47S	47	Missense	proximal	1	no	146.918	-133.876	EPSD	TCGA;ICGC;COSMIC	140.458	Loss
CMGC_MAPK_JNK_MAPK9_ST	P10636	MAPT	P45984	MAPK9	S46	P47L	47	Missense	proximal	1	no	146.918	102.015	EPSD	TCGA;ICGC;COSMIC	140.458	Loss
CMGC_MAPK_JNK_MAPK9_ST	P10636	MAPT	P45984	MAPK9	S46	G42C	42	Missense	distal	-4	no	146.918	147.181	EPSD	TCGA;ICGC;COSMIC	140.458	Up-regulation
CMGC_MAPK_JNK_MAPK9_ST	P10636	MAPT	P45984	MAPK9	T50	D54E	54	Missense	distal	4	no	156.013	155.647	EPSD	TCGA;ICGC;COSMIC	140.458	Down-regulation
CMGC_MAPK_JNK_MAPK9_ST	P10636	MAPT	P45984	MAPK9	T50	T52I	52	Missense	proximal	2	no	156.013	155.984	EPSD	TCGA;ICGC;COSMIC	140.458	Down-regulation
CMGC_MAPK_JNK_MAPK9_ST	P10636	MAPT	P45984	MAPK9	T50	P47S	47	Missense	distal	-3	no	156.013	154.974	EPSD	TCGA;ICGC;COSMIC	140.458	Down-regulation
CMGC_MAPK_JNK_MAPK9_ST	P10636	MAPT	P45984	MAPK9	T50	P47L	47	Missense	distal	-3	no	156.013	154.440	EPSD	TCGA;ICGC;COSMIC	140.458	Down-regulation
CMGC_MAPK_JNK_MAPK9_ST	P10636	MAPT	P45984	MAPK9	T50	G55R	55	Missense	distal	5	no	156.013	155.205	EPSD	TCGA;ICGC;COSMIC	140.458	Down-regulation
CMGC_MAPK_JNK_MAPK9_ST	P10636	MAPT	P45984	MAPK9	S64	A66S	66	Missense	proximal	2	no	144.805	144.890	EPSD	TCGA;ICGC;COSMIC	140.458	Up-regulation
CMGC_MAPK_JNK_MAPK9_ST	P10636	MAPT	P45984	MAPK9	S64	P59L	59	Missense	distal	-5	no	144.805	144.905	EPSD	TCGA;ICGC;COSMIC	140.458	Up-regulation
CMGC_MAPK_JNK_MAPK9_ST	P10636	MAPT	P45984	MAPK9	S64	P59T	59	Missense	distal	-5	no	144.805	144.831	EPSD	TCGA;ICGC;COSMIC	140.458	Up-regulation
CMGC_MAPK_JNK_MAPK9_ST	P10636	MAPT	P45984	MAPK9	S64	G60S	60	Missense	distal	-4	no	144.805	146.339	EPSD	TCGA;ICGC;COSMIC	140.458	Up-regulation
CMGC_MAPK_JNK_MAPK9_ST	P10636	MAPT	P45984	MAPK9	S68	A72V	72	Missense	distal	4	no	141.235	141.460	EPSD	TCGA;ICGC;COSMIC	140.458	Up-regulation
CMGC_MAPK_JNK_MAPK9_ST	P10636	MAPT	P45984	MAPK9	S68	A66S	66	Missense	proximal	-2	no	141.235	138.745	EPSD	TCGA;ICGC;COSMIC	140.458	Loss
CMGC_MAPK_JNK_MAPK9_ST	P10636	MAPT	P45984	MAPK9	T69	A72V	72	Missense	distal	3	no	157.136	156.962	EPSD	TCGA;ICGC;COSMIC	140.458	Down-regulation
CMGC_MAPK_JNK_MAPK9_ST	P10636	MAPT	P45984	MAPK9	T69	A66S	66	Missense	distal	-3	no	157.136	156.722	EPSD	TCGA;ICGC;COSMIC	140.458	Down-regulation
CMGC_MAPK_JNK_MAPK9_ST	P10636	MAPT	P45984	MAPK9	T95	H94R	94	Missense	proximal	-1	no	144.342	144.610	EPSD	TCGA;ICGC;COSMIC	140.458	Up-regulation
CMGC_MAPK_JNK_MAPK9_ST	P10636	MAPT	P45984	MAPK9	T95	A89S	89	Missense	distal	-6	no	144.342	144.255	EPSD	TCGA;ICGC;COSMIC	140.458	Down-regulation
CMGC_MAPK_JNK_MAPK9_ST	P10636	MAPT	P45984	MAPK9	T95	A91V	91	Missense	distal	-4	no	144.342	142.685	EPSD	TCGA;ICGC;COSMIC	140.458	Down-regulation
CMGC_MAPK_JNK_MAPK9_ST	P10636	MAPT	P45984	MAPK9	T101	H94R	94	Missense	distal	-7	no	140.133	141.878	EPSD	TCGA;ICGC;COSMIC	140.458	Gain
CMGC_MAPK_JNK_MAPK9_ST	P10636	MAPT	P45984	MAPK9	T111	E117K	117	Missense	distal	6	no	150.649	150.495	EPSD	TCGA;ICGC;COSMIC	140.458	Down-regulation
CMGC_MAPK_JNK_MAPK9_ST	P10636	MAPT	P45984	MAPK9	T111	A118V	118	Missense	distal	7	no	150.649	151.323	EPSD	TCGA;ICGC;COSMIC	140.458	Up-regulation
CMGC_MAPK_JNK_MAPK9_ST	P10636	MAPT	P45984	MAPK9	S228	S232Y	232	Missense	distal	4	no	156.450	156.956	EPSD	TCGA;ICGC;COSMIC	140.458	Up-regulation
CMGC_MAPK_JNK_MAPK9_ST	P10636	MAPT	P45984	MAPK9	S228	D223Y	223	Missense	distal	-5	no	156.450	156.505	EPSD	TCGA;ICGC;COSMIC	140.458	Up-regulation
CMGC_MAPK_JNK_MAPK9_ST	P10636	MAPT	P45984	MAPK9	S228	S227F	227	Missense	proximal	-1	no	156.450	156.074	EPSD	TCGA;ICGC;COSMIC	140.458	Down-regulation
CMGC_MAPK_JNK_MAPK9_ST	P10636	MAPT	P45984	MAPK9	S228	P234L	234	Missense	distal	6	no	156.450	156.217	EPSD	TCGA;ICGC;COSMIC	140.458	Down-regulation
CMGC_MAPK_JNK_MAPK9_ST	P10636	MAPT	P45984	MAPK9	S232	S232Y	232	Missense	central	0	yes	154.055	0.000	EPSD	TCGA;ICGC;COSMIC	140.458	Loss
CMGC_MAPK_JNK_MAPK9_ST	P10636	MAPT	P45984	MAPK9	S232	S227F	227	Missense	distal	-5	no	154.055	154.198	EPSD	TCGA;ICGC;COSMIC	140.458	Up-regulation
CMGC_MAPK_JNK_MAPK9_ST	P10636	MAPT	P45984	MAPK9	S232	P234L	234	Missense	proximal	2	no	154.055	154.210	EPSD	TCGA;ICGC;COSMIC	140.458	Up-regulation
CMGC_MAPK_JNK_MAPK9_ST	P10636	MAPT	P45984	MAPK9	S238	S232Y	232	Missense	distal	-6	no	155.330	154.652	EPSD	TCGA;ICGC;COSMIC	140.458	Down-regulation
CMGC_MAPK_JNK_MAPK9_ST	P10636	MAPT	P45984	MAPK9	S238	A240T	240	Missense	proximal	2	no	155.330	155.496	EPSD	TCGA;ICGC;COSMIC	140.458	Up-regulation
CMGC_MAPK_JNK_MAPK9_ST	P10636	MAPT	P45984	MAPK9	S238	P234L	234	Missense	distal	-4	no	155.330	153.318	EPSD	TCGA;ICGC;COSMIC	140.458	Down-regulation
CMGC_MAPK_JNK_MAPK9_ST	P10636	MAPT	P45984	MAPK9	S238	R244Q	244	Missense	distal	6	no	155.330	155.498	EPSD	TCGA;ICGC;COSMIC	140.458	Up-regulation
CMGC_MAPK_JNK_MAPK9_ST	P10636	MAPT	P45984	MAPK9	T248	R244Q	244	Missense	distal	-4	no	146.145	147.576	EPSD	TCGA;ICGC;COSMIC	140.458	Up-regulation
CMGC_MAPK_JNK_MAPK9_ST	P10636	MAPT	P45984	MAPK9	S411	P415L	415	Missense	distal	4	no	157.243	157.619	EPSD	TCGA;ICGC;COSMIC	140.458	Up-regulation
CMGC_MAPK_JNK_MAPK9_ST	P10636	MAPT	P45984	MAPK9	T416	P415L	415	Missense	proximal	-1	no	153.449	153.293	EPSD	TCGA;ICGC;COSMIC	140.458	Down-regulation
CMGC_MAPK_JNK_MAPK9_ST	P10636	MAPT	P45984	MAPK9	S428	A430S	430	Missense	proximal	2	no	156.636	156.721	EPSD	TCGA;ICGC;COSMIC	140.458	Up-regulation
CMGC_MAPK_JNK_MAPK9_ST	P10636	MAPT	P45984	MAPK9	S428	V431L	431	Missense	distal	3	no	156.636	156.452	EPSD	TCGA;ICGC;COSMIC	140.458	Down-regulation
CMGC_MAPK_JNK_MAPK9_ST	P10636	MAPT	P45984	MAPK9	S428	A430V	430	Missense	proximal	2	no	156.636	156.777	EPSD	TCGA;ICGC;COSMIC	140.458	Up-regulation
CMGC_MAPK_JNK_MAPK9_ST	P10636	MAPT	P45984	MAPK9	S438	P436T	436	Missense	proximal	-2	no	167.104	163.468	EPSD	TCGA;ICGC;COSMIC	140.458	Down-regulation
CMGC_MAPK_JNK_MAPK9_ST	P10636	MAPT	P45984	MAPK9	S438	P436L	436	Missense	proximal	-2	no	167.104	166.030	EPSD	TCGA;ICGC;COSMIC	140.458	Down-regulation
CMGC_MAPK_JNK_MAPK9_ST	P10636	MAPT	P45984	MAPK9	S438	K440E	440	Missense	proximal	2	no	167.104	167.073	EPSD	TCGA;ICGC;COSMIC	140.458	Down-regulation
CMGC_MAPK_JNK_MAPK9_ST	P10636	MAPT	P45984	MAPK9	S438	S443F	443	Missense	distal	5	no	167.104	168.292	EPSD	TCGA;ICGC;COSMIC	140.458	Up-regulation
CMGC_MAPK_JNK_MAPK9_ST	P10636	MAPT	P45984	MAPK9	S438	V431L	431	Missense	distal	-7	no	167.104	165.907	EPSD	TCGA;ICGC;COSMIC	140.458	Down-regulation
CMGC_MAPK_JNK_MAPK9_ST	P10636	MAPT	P45984	MAPK9	S438	S444F	444	Missense	distal	6	no	167.104	166.554	EPSD	TCGA;ICGC	140.458	Down-regulation
CMGC_MAPK_JNK_MAPK9_ST	P10636	MAPT	P45984	MAPK9	T470	R472Q	472	Missense	proximal	2	no	149.411	149.456	EPSD	TCGA	140.458	Up-regulation
CMGC_MAPK_JNK_MAPK9_ST	P10636	MAPT	P45984	MAPK9	T470	R472W	472	Missense	proximal	2	no	149.411	149.738	EPSD	TCGA;COSMIC	140.458	Up-regulation
CMGC_MAPK_JNK_MAPK9_ST	P10636	MAPT	P45984	MAPK9	T492	A485T	485	Missense	distal	-7	no	157.759	155.216	EPSD	TCGA;COSMIC;GDSC;CCLE	140.458	Down-regulation
CMGC_MAPK_JNK_MAPK9_ST	P10636	MAPT	P45984	MAPK9	T492	P493Q	493	Missense	proximal	1	no	157.759	137.647	EPSD	TCGA;COSMIC	140.458	Loss
CMGC_MAPK_JNK_MAPK9_ST	P10636	MAPT	P45984	MAPK9	T498	P493Q	493	Missense	distal	-5	no	166.420	166.396	EPSD	TCGA;COSMIC	140.458	Down-regulation
CMGC_MAPK_JNK_MAPK9_ST	P15336	ATF2	P45984	MAPK9	T69	P70S	70	Missense	proximal	1	no	157.619	-123.175	PhosphoSitePlus;EPSD	TCGA;COSMIC	140.458	Loss
CMGC_MAPK_JNK_MAPK9_ST	P15336	ATF2	P45984	MAPK9	T71	P70S	70	Missense	proximal	-1	no	157.277	157.164	EPSD;PhosphoSitePlus	TCGA;COSMIC	140.458	Down-regulation
CMGC_MAPK_JNK_MAPK9_ST	P15336	ATF2	P45984	MAPK9	S90	E93Q	93	Missense	distal	3	no	161.846	161.942	EPSD;PhosphoSitePlus	TCGA;COSMIC	140.458	Up-regulation
CMGC_MAPK_JNK_MAPK9_ST	P15336	ATF2	P45984	MAPK9	S90	G83D	83	Missense	distal	-7	no	161.846	161.681	EPSD;PhosphoSitePlus	TCGA;COSMIC	140.458	Down-regulation
CMGC_MAPK_JNK_MAPK9_ST	P15336	ATF2	P45984	MAPK9	S112	T116A	116	Missense	distal	4	no	155.989	155.817	EPSD	TCGA;COSMIC	140.458	Down-regulation
CMGC_MAPK_JNK_MAPK9_ST	P15336	ATF2	P45984	MAPK9	S112	S112P	112	Missense	central	0	yes	155.989	0.000	EPSD	TCGA;COSMIC	140.458	Loss
CMGC_MAPK_JNK_MAPK9_ST	P15336	ATF2	P45984	MAPK9	T116	T116A	116	Missense	central	0	yes	159.246	0.000	EPSD	TCGA;COSMIC	140.458	Loss
CMGC_MAPK_JNK_MAPK9_ST	P15336	ATF2	P45984	MAPK9	T116	S112P	112	Missense	distal	-4	no	159.246	159.067	EPSD	TCGA;COSMIC	140.458	Down-regulation
CMGC_MAPK_JNK_MAPK9_ST	P15336	ATF2	P45984	MAPK9	T131	D135N	135	Missense	distal	4	no	141.821	141.503	EPSD	TCGA	140.458	Down-regulation
CMGC_MAPK_JNK_MAPK9_ST	P15336	ATF2	P45984	MAPK9	T131	S136N	136	Missense	distal	5	no	141.821	141.591	EPSD	TCGA	140.458	Down-regulation
CMGC_MAPK_JNK_MAPK9_ST	P15336	ATF2	P45984	MAPK9	S136	D135N	135	Missense	proximal	-1	no	153.807	154.119	EPSD	TCGA	140.458	Up-regulation
CMGC_MAPK_JNK_MAPK9_ST	P15336	ATF2	P45984	MAPK9	S136	S136N	136	Missense	central	0	yes	153.807	0.000	EPSD	TCGA	140.458	Loss
CMGC_MAPK_JNK_MAPK9_ST	P15336	ATF2	P45984	MAPK9	S143	S136N	136	Missense	distal	-7	no	138.719	140.605	EPSD	TCGA	140.458	Gain
CMGC_MAPK_JNK_MAPK9_ST	P15336	ATF2	P45984	MAPK9	S266	G260E	260	Missense	distal	-6	no	157.676	158.020	EPSD	TCGA;COSMIC	140.458	Up-regulation
CMGC_MAPK_JNK_MAPK9_ST	P15336	ATF2	P45984	MAPK9	S266	P267S	267	Missense	proximal	1	no	157.676	-123.118	EPSD	TCGA;COSMIC	140.458	Loss
CMGC_MAPK_JNK_MAPK9_ST	P15336	ATF2	P45984	MAPK9	S266	G263C	263	Missense	distal	-3	no	157.676	158.101	EPSD	TCGA;COSMIC	140.458	Up-regulation
CMGC_MAPK_JNK_MAPK9_ST	P15336	ATF2	P45984	MAPK9	T283	P288S	288	Missense	distal	5	no	144.509	144.567	EPSD	TCGA;COSMIC	140.458	Up-regulation
CMGC_MAPK_JNK_MAPK9_ST	P15336	ATF2	P45984	MAPK9	T325	P326S	326	Missense	proximal	1	no	157.279	-123.515	EPSD	TCGA;COSMIC	140.458	Loss
CMGC_MAPK_JNK_MAPK9_ST	P15336	ATF2	P45984	MAPK9	T325	S321F	321	Missense	distal	-4	no	157.279	153.996	EPSD	TCGA;COSMIC	140.458	Down-regulation
CMGC_MAPK_JNK_MAPK9_ST	P15336	ATF2	P45984	MAPK9	S328	P326S	326	Missense	proximal	-2	no	160.859	157.098	EPSD	TCGA;COSMIC	140.458	Down-regulation
CMGC_MAPK_JNK_MAPK9_ST	P15336	ATF2	P45984	MAPK9	S328	P334A	334	Missense	distal	6	no	160.859	161.022	EPSD	TCGA;COSMIC	140.458	Up-regulation
CMGC_MAPK_JNK_MAPK9_ST	P15336	ATF2	P45984	MAPK9	S328	S321F	321	Missense	distal	-7	no	160.859	157.920	EPSD	TCGA;COSMIC	140.458	Down-regulation
CMGC_MAPK_JNK_MAPK9_ST	P15336	ATF2	P45984	MAPK9	T333	P326S	326	Missense	distal	-7	no	152.446	153.477	EPSD	TCGA;COSMIC	140.458	Up-regulation
CMGC_MAPK_JNK_MAPK9_ST	P15336	ATF2	P45984	MAPK9	T333	P334A	334	Missense	proximal	1	no	152.446	133.803	EPSD	TCGA;COSMIC	140.458	Loss
CMGC_MAPK_JNK_MAPK9_ST	P15336	ATF2	P45984	MAPK9	T333	T339A	339	Missense	distal	6	no	152.446	152.859	EPSD	TCGA;COSMIC	140.458	Up-regulation
CMGC_MAPK_JNK_MAPK9_ST	P15336	ATF2	P45984	MAPK9	S338	P334A	334	Missense	distal	-4	no	141.803	142.537	EPSD	TCGA;COSMIC	140.458	Up-regulation
CMGC_MAPK_JNK_MAPK9_ST	P15336	ATF2	P45984	MAPK9	S338	T339A	339	Missense	proximal	1	no	141.803	142.355	EPSD	TCGA;COSMIC	140.458	Up-regulation
CMGC_MAPK_JNK_MAPK9_ST	P15336	ATF2	P45984	MAPK9	S446	Q453H	453	Missense	distal	7	no	154.824	155.178	EPSD	TCGA;COSMIC	140.458	Up-regulation
CMGC_MAPK_JNK_MAPK9_ST	P15336	ATF2	P45984	MAPK9	S500	P502L	502	Missense	proximal	2	no	140.314	140.469	EPSD	TCGA;COSMIC	140.458	Gain
CMGC_MAPK_JNK_MAPK9_ST	P15336	ATF2	P45984	MAPK9	S500	P502T	502	Missense	proximal	2	no	140.314	140.490	EPSD	TCGA;COSMIC	140.458	Gain
CMGC_MAPK_JNK_MAPK9_ST	P01106	MYC	P45984	MAPK9	T58	E54D	54	Missense	distal	-4	no	162.904	161.984	EPSD	TCGA;ICGC;COSMIC;GDSC	140.458	Down-regulation
CMGC_MAPK_JNK_MAPK9_ST	P01106	MYC	P45984	MAPK9	S161	S161L	161	Missense	central	0	yes	150.506	0.000	EPSD	TCGA;ICGC;COSMIC	140.458	Loss
CMGC_MAPK_JNK_MAPK9_ST	P01106	MYC	P45984	MAPK9	S204	S207L	207	Missense	distal	3	no	148.093	147.832	EPSD	TCGA;ICGC;COSMIC	140.458	Down-regulation
CMGC_MAPK_JNK_MAPK9_ST	P01106	MYC	P45984	MAPK9	S344	K341R	341	Missense	distal	-3	no	151.903	153.704	EPSD	TCGA;ICGC;COSMIC	140.458	Up-regulation
CMGC_MAPK_JNK_MAPK9_ST	P01106	MYC	P45984	MAPK9	S348	K341R	341	Missense	distal	-7	no	148.262	148.392	EPSD	TCGA;ICGC;COSMIC	140.458	Up-regulation
CMGC_MAPK_JNK_MAPK9_ST	P05067	APP	P45984	MAPK9	T274	A273T	273	Missense	proximal	-1	no	141.263	141.003	EPSD	TCGA	140.458	Down-regulation
CMGC_MAPK_JNK_MAPK9_ST	P05067	APP	P45984	MAPK9	T274	T274A	274	Missense	central	0	yes	141.263	0.000	EPSD	TCGA;COSMIC;CCLE	140.458	Loss
CMGC_MAPK_JNK_MAPK9_ST	P05067	APP	P45984	MAPK9	T275	A273T	273	Missense	proximal	-2	no	140.615	138.248	EPSD	TCGA	140.458	Loss
CMGC_MAPK_JNK_MAPK9_ST	P05067	APP	P45984	MAPK9	T275	T274A	274	Missense	proximal	-1	no	140.615	140.875	EPSD	TCGA;COSMIC;CCLE	140.458	Up-regulation
CMGC_MAPK_JNK_MAPK9_ST	P05067	APP	P45984	MAPK9	T277	A273T	273	Missense	distal	-4	no	140.603	137.977	EPSD	TCGA	140.458	Loss
CMGC_MAPK_JNK_MAPK9_ST	P05067	APP	P45984	MAPK9	T277	E284K	284	Missense	distal	7	no	140.603	140.853	EPSD	TCGA;COSMIC	140.458	Up-regulation
CMGC_MAPK_JNK_MAPK9_ST	P05067	APP	P45984	MAPK9	T277	T274A	274	Missense	distal	-3	no	140.603	141.850	EPSD	TCGA;COSMIC;CCLE	140.458	Up-regulation
CMGC_MAPK_JNK_MAPK9_ST	P05067	APP	P45984	MAPK9	T381	E380K	380	Missense	proximal	-1	no	152.510	152.392	EPSD	TCGA;COSMIC;CCLE	140.458	Down-regulation
CMGC_MAPK_JNK_MAPK9_ST	P05067	APP	P45984	MAPK9	S573	Q567H	567	Missense	distal	-6	no	143.502	143.133	EPSD	TCGA;COSMIC	140.458	Down-regulation
CMGC_MAPK_JNK_MAPK9_ST	P05067	APP	P45984	MAPK9	S573	M580V	580	Missense	distal	7	no	143.502	143.931	EPSD	TCGA;COSMIC	140.458	Up-regulation
CMGC_MAPK_JNK_MAPK9_ST	P05067	APP	P45984	MAPK9	T598	E599Q	599	Missense	proximal	1	no	140.137	140.917	EPSD	TCGA;COSMIC	140.458	Gain
CMGC_MAPK_JNK_MAPK9_ST	P05067	APP	P45984	MAPK9	T743	R747P	747	Missense	distal	4	no	158.371	158.382	EPSD	TCGA;COSMIC	140.458	Up-regulation
CMGC_MAPK_JNK_MAPK9_ST	P05067	APP	P45984	MAPK9	T743	R747C	747	Missense	distal	4	no	158.371	158.628	EPSD	TCGA;COSMIC;GDSC	140.458	Up-regulation
CMGC_MAPK_JNK_MAPK9_ST	P05067	APP	P45984	MAPK9	T743	R747H	747	Missense	distal	4	no	158.371	158.652	EPSD	TCGA;COSMIC	140.458	Up-regulation
CMGC_MAPK_JNK_MAPK9_ST	P49768	PSEN1	P45984	MAPK9	S319	E321K	321	Missense	proximal	2	no	148.450	148.481	EPSD;PhosphoSitePlus	TCGA;COSMIC	140.458	Up-regulation
CMGC_MAPK_JNK_MAPK9_ST	P49768	PSEN1	P45984	MAPK9	S319	S313F	313	Missense	distal	-6	no	148.450	147.752	EPSD;PhosphoSitePlus	TCGA	140.458	Down-regulation
CMGC_MAPK_JNK_MAPK9_ST	P49768	PSEN1	P45984	MAPK9	T320	E321K	321	Missense	proximal	1	no	150.247	2.223	PhosphoSitePlus;EPSD	TCGA;COSMIC	140.458	Loss
CMGC_MAPK_JNK_MAPK9_ST	P49768	PSEN1	P45984	MAPK9	T320	S313F	313	Missense	distal	-7	no	150.247	147.308	PhosphoSitePlus;EPSD	TCGA	140.458	Down-regulation
CMGC_MAPK_JNK_MAPK9_ST	P49768	PSEN1	P45984	MAPK9	T354	P355A	355	Missense	proximal	1	no	149.829	131.186	EPSD	TCGA;COSMIC	140.458	Loss
CMGC_MAPK_JNK_MAPK9_ST	P38936	CDKN1A	P45984	MAPK9	T57	G61V	61	Missense	distal	4	no	162.997	162.940	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	140.458	Down-regulation
CMGC_MAPK_JNK_MAPK9_ST	P38936	CDKN1A	P45984	MAPK9	T57	E56K	56	Missense	proximal	-1	no	162.997	162.878	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	140.458	Down-regulation
CMGC_MAPK_JNK_MAPK9_ST	P38936	CDKN1A	P45984	MAPK9	T57	P58L	58	Missense	proximal	1	no	162.997	118.094	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	140.458	Loss
CMGC_MAPK_JNK_MAPK9_ST	P38936	CDKN1A	P45984	MAPK9	S98	R94W	94	Missense	distal	-4	no	156.917	153.587	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	140.458	Down-regulation
CMGC_MAPK_JNK_MAPK9_ST	P38936	CDKN1A	P45984	MAPK9	S98	R93S	93	Missense	distal	-5	no	156.917	156.905	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	140.458	Down-regulation
CMGC_MAPK_JNK_MAPK9_ST	P38936	CDKN1A	P45984	MAPK9	S98	R94P	94	Missense	distal	-4	no	156.917	157.036	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	140.458	Up-regulation
CMGC_MAPK_JNK_MAPK9_ST	P38936	CDKN1A	P45984	MAPK9	S98	P95S	95	Missense	distal	-3	no	156.917	155.878	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	140.458	Down-regulation
CMGC_MAPK_JNK_MAPK9_ST	P38936	CDKN1A	P45984	MAPK9	S130	D136H	136	Missense	distal	6	no	156.548	156.456	PhosphoSitePlus;EPSD	TCGA;ICGC;COSMIC	140.458	Down-regulation
CMGC_MAPK_JNK_MAPK9_ST	P38936	CDKN1A	P45984	MAPK9	S130	G132C	132	Missense	proximal	2	no	156.548	156.524	PhosphoSitePlus;EPSD	TCGA;ICGC;COSMIC	140.458	Down-regulation
CMGC_MAPK_JNK_MAPK9_ST	P38936	CDKN1A	P45984	MAPK9	S130	E128K	128	Missense	proximal	-2	no	156.548	154.480	PhosphoSitePlus;EPSD	TCGA;ICGC;COSMIC	140.458	Down-regulation
CMGC_MAPK_JNK_MAPK9_ST	P38936	CDKN1A	P45984	MAPK9	S130	G135A	135	Missense	distal	5	no	156.548	155.983	PhosphoSitePlus;EPSD	TCGA	140.458	Down-regulation
CMGC_MAPK_JNK_MAPK9_ST	P38936	CDKN1A	P45984	MAPK9	S137	G135A	135	Missense	proximal	-2	no	140.385	142.982	EPSD	TCGA	140.458	Gain
CMGC_MAPK_JNK_MAPK9_ST	P38936	CDKN1A	P45984	MAPK9	S137	R142W	142	Missense	distal	5	no	140.385	141.736	EPSD	TCGA;ICGC;COSMIC;GDSC;CCLE	140.458	Gain
CMGC_MAPK_JNK_MAPK9_ST	P19793	RXRA	P45984	MAPK9	S21	S27C	27	Missense	distal	6	no	156.099	155.962	EPSD	TCGA;ICGC;COSMIC	140.458	Down-regulation
CMGC_MAPK_JNK_MAPK9_ST	P19793	RXRA	P45984	MAPK9	S21	Q14K	14	Missense	distal	-7	no	156.099	156.041	EPSD	TCGA;ICGC;COSMIC	140.458	Down-regulation
CMGC_MAPK_JNK_MAPK9_ST	P19793	RXRA	P45984	MAPK9	S21	Q14L	14	Missense	distal	-7	no	156.099	153.433	EPSD	TCGA;ICGC;COSMIC	140.458	Down-regulation
CMGC_MAPK_JNK_MAPK9_ST	P19793	RXRA	P45984	MAPK9	S49	L47V	47	Missense	proximal	-2	no	158.363	155.162	EPSD	TCGA;ICGC;COSMIC	140.458	Down-regulation
CMGC_MAPK_JNK_MAPK9_ST	P19793	RXRA	P45984	MAPK9	S49	S43F	43	Missense	distal	-6	no	158.363	157.664	EPSD	TCGA;ICGC;COSMIC	140.458	Down-regulation
CMGC_MAPK_JNK_MAPK9_ST	P19793	RXRA	P45984	MAPK9	T82	S78L	78	Missense	distal	-4	no	155.980	153.789	EPSD	TCGA;ICGC;COSMIC	140.458	Down-regulation
CMGC_MAPK_JNK_MAPK9_ST	P19793	RXRA	P45984	MAPK9	T82	M77V	77	Missense	distal	-5	no	155.980	156.067	EPSD	TCGA;ICGC	140.458	Up-regulation
CMGC_MAPK_JNK_MAPK9_ST	P19793	RXRA	P45984	MAPK9	S222	A226T	226	Missense	distal	4	no	142.947	143.118	EPSD	TCGA;ICGC;COSMIC;GDSC	140.458	Up-regulation
CMGC_MAPK_JNK_MAPK9_ST	P19793	RXRA	P45984	MAPK9	S225	P231L	231	Missense	distal	6	no	141.453	141.221	EPSD	TCGA;ICGC;COSMIC	140.458	Down-regulation
CMGC_MAPK_JNK_MAPK9_ST	P19793	RXRA	P45984	MAPK9	S225	A226T	226	Missense	proximal	1	no	141.453	140.901	EPSD	TCGA;ICGC;COSMIC;GDSC	140.458	Down-regulation
CMGC_MAPK_JNK_MAPK9_ST	P19793	RXRA	P45984	MAPK9	T246	Y249F	249	Missense	distal	3	no	141.683	141.731	EPSD	TCGA;ICGC;COSMIC	140.458	Up-regulation
CMGC_MAPK_JNK_MAPK9_ST	P19793	RXRA	P45984	MAPK9	S260	V265I	265	Missense	distal	5	no	163.067	163.286	PhosphoSitePlus	TCGA	140.458	Up-regulation
CMGC_MAPK_JNK_MAPK9_ST	P19793	RXRA	P45984	MAPK9	S260	G255W	255	Missense	distal	-5	no	163.067	163.145	PhosphoSitePlus	TCGA;ICGC	140.458	Up-regulation
CMGC_MAPK_JNK_MAPK9_ST	Q8WYK2	JDP2	P45984	MAPK9	T143	R136L	136	Missense	distal	-7	no	141.208	138.469	EPSD	TCGA;ICGC;COSMIC	140.458	Loss
CMGC_MAPK_JNK_MAPK9_ST	P50616	TOB1	P45984	MAPK9	S152	S147L	147	Missense	distal	-5	no	159.585	159.704	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	140.458	Up-regulation
CMGC_MAPK_JNK_MAPK9_ST	P50616	TOB1	P45984	MAPK9	S154	S147L	147	Missense	distal	-7	no	161.569	159.410	PhosphoSitePlus;EPSD	TCGA;ICGC;COSMIC	140.458	Down-regulation
CMGC_MAPK_JNK_MAPK9_ST	P50616	TOB1	P45984	MAPK9	S164	S164N	164	Missense	central	0	yes	161.971	0.000	EPSD;PhosphoSitePlus	TCGA	140.458	Loss
CMGC_MAPK_JNK_MAPK9_ST	P50616	TOB1	P45984	MAPK9	S164	M168V	168	Missense	distal	4	no	161.971	162.261	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	140.458	Up-regulation
CMGC_MAPK_JNK_MAPK9_ST	P50616	TOB1	P45984	MAPK9	S205	S205F	205	Missense	central	0	yes	155.937	0.000	EPSD	TCGA;ICGC;COSMIC	140.458	Loss
CMGC_MAPK_JNK_MAPK9_ST	P50616	TOB1	P45984	MAPK9	S205	N208S	208	Missense	distal	3	no	155.937	155.809	EPSD	TCGA;ICGC;COSMIC	140.458	Down-regulation
CMGC_MAPK_JNK_MAPK9_ST	P50616	TOB1	P45984	MAPK9	S205	G210R	210	Missense	distal	5	no	155.937	155.129	EPSD	TCGA;ICGC;COSMIC	140.458	Down-regulation
CMGC_MAPK_JNK_MAPK9_ST	P50616	TOB1	P45984	MAPK9	S205	L209F	209	Missense	distal	4	no	155.937	156.168	EPSD	TCGA;ICGC;COSMIC	140.458	Up-regulation
CMGC_MAPK_JNK_MAPK9_ST	P50616	TOB1	P45984	MAPK9	S205	V201A	201	Missense	distal	-4	no	155.937	157.594	EPSD	TCGA;ICGC	140.458	Up-regulation
CMGC_MAPK_JNK_MAPK9_ST	P50616	TOB1	P45984	MAPK9	S205	R203H	203	Missense	proximal	-2	no	155.937	153.110	EPSD	TCGA;ICGC	140.458	Down-regulation
CMGC_MAPK_JNK_MAPK9_ST	P50616	TOB1	P45984	MAPK9	S205	K200N	200	Missense	distal	-5	no	155.937	155.891	EPSD	TCGA;ICGC	140.458	Down-regulation
CMGC_MAPK_JNK_MAPK9_ST	P50616	TOB1	P45984	MAPK9	S268	S265T	265	Missense	distal	-3	no	168.357	167.522	EPSD	TCGA;ICGC;COSMIC	140.458	Down-regulation
CMGC_MAPK_JNK_MAPK9_ST	Q07817	BCL2L1	P45984	MAPK9	T47	A50V	50	Missense	distal	3	no	161.645	161.471	PhosphoSitePlus;EPSD	TCGA;ICGC;COSMIC	140.458	Down-regulation
CMGC_MAPK_JNK_MAPK9_ST	Q07817	BCL2L1	P45984	MAPK9	S62	A64V	64	Missense	proximal	2	no	156.992	157.133	EPSD;PhosphoSitePlus	TCGA	140.458	Up-regulation
CMGC_MAPK_JNK_MAPK9_ST	Q07817	BCL2L1	P45984	MAPK9	T115	T109A	109	Missense	distal	-6	no	161.408	161.762	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	140.458	Up-regulation
CMGC_MAPK_JNK_MAPK9_ST	Q07817	BCL2L1	P45984	MAPK9	T115	Q121P	121	Missense	distal	6	no	161.408	161.176	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	140.458	Down-regulation
CMGC_MAPK_JNK_MAPK9_ST	Q07817	BCL2L1	P45984	MAPK9	T115	Q121H	121	Missense	distal	6	no	161.408	160.949	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	140.458	Down-regulation
CMGC_MAPK_JNK_MAPK9_ST	Q14934	NFATC4	P45984	MAPK9	S819	G824V	824	Missense	distal	5	no	163.760	163.611	EPSD	TCGA;COSMIC	140.458	Down-regulation
CMGC_MAPK_JNK_MAPK9_ST	Q9UGP4	LIMD1	P45984	MAPK9	S187	G191D	191	Missense	distal	4	no	148.491	148.569	EPSD	TCGA;ICGC;COSMIC	140.458	Up-regulation
CMGC_MAPK_JNK_MAPK9_ST	Q9UGP4	LIMD1	P45984	MAPK9	S197	G201S	201	Missense	distal	4	no	146.722	146.514	EPSD	TCGA;ICGC	140.458	Down-regulation
CMGC_MAPK_JNK_MAPK9_ST	Q9UGP4	LIMD1	P45984	MAPK9	S197	G191D	191	Missense	distal	-6	no	146.722	146.504	EPSD	TCGA;ICGC;COSMIC	140.458	Down-regulation
CMGC_MAPK_JNK_MAPK9_ST	Q9UGP4	LIMD1	P45984	MAPK9	S277	L280V	280	Missense	distal	3	no	153.250	153.434	PhosphoSitePlus;EPSD	TCGA	140.458	Up-regulation
CMGC_MAPK_JNK_MAPK9_ST	Q9UGP4	LIMD1	P45984	MAPK9	S277	N282S	282	Missense	distal	5	no	153.250	153.479	PhosphoSitePlus;EPSD	TCGA;ICGC;COSMIC	140.458	Up-regulation
CMGC_MAPK_JNK_MAPK9_ST	Q9UGP4	LIMD1	P45984	MAPK9	T294	S296F	296	Missense	proximal	2	no	159.787	160.024	EPSD	TCGA;ICGC;COSMIC	140.458	Up-regulation
CMGC_MAPK_JNK_MAPK9_ST	Q9UGP4	LIMD1	P45984	MAPK9	S298	S296F	296	Missense	proximal	-2	no	142.141	139.871	EPSD	TCGA;ICGC;COSMIC	140.458	Loss
CMGC_MAPK_JNK_MAPK9_ST	Q9UGP4	LIMD1	P45984	MAPK9	S353	S360L	360	Missense	distal	7	no	153.938	154.349	EPSD	TCGA;ICGC;COSMIC	140.458	Up-regulation
CMGC_MAPK_JNK_MAPK9_ST	Q9UGP4	LIMD1	P45984	MAPK9	S353	S347R	347	Missense	distal	-6	no	153.938	154.141	EPSD	TCGA;ICGC;COSMIC	140.458	Up-regulation
CMGC_MAPK_JNK_MAPK9_ST	Q9UGP4	LIMD1	P45984	MAPK9	S353	S346F	346	Missense	distal	-7	no	153.938	150.999	EPSD	TCGA;ICGC;COSMIC	140.458	Down-regulation
CMGC_MAPK_JNK_MAPK9_ST	Q9UGP4	LIMD1	P45984	MAPK9	T375	C374Y	374	Missense	proximal	-1	no	140.658	140.380	EPSD	TCGA;ICGC;COSMIC	140.458	Loss
CMGC_MAPK_JNK_MAPK9_ST	Q9UGP4	LIMD1	P45984	MAPK9	S384	L388F	388	Missense	distal	4	no	154.677	154.908	EPSD	TCGA;ICGC;COSMIC	140.458	Up-regulation
CMGC_MAPK_JNK_MAPK9_ST	Q9UGP4	LIMD1	P45984	MAPK9	S384	S387N	387	Missense	distal	3	no	154.677	154.805	EPSD	TCGA;ICGC	140.458	Up-regulation
CMGC_MAPK_JNK_MAPK9_ST	Q9UGP4	LIMD1	P45984	MAPK9	S421	R428M	428	Missense	distal	7	no	148.618	148.981	EPSD;PhosphoSitePlus	TCGA;ICGC	140.458	Up-regulation
CMGC_MAPK_JNK_MAPK9_ST	Q9UGP4	LIMD1	P45984	MAPK9	S424	R428M	428	Missense	distal	4	no	154.717	154.691	EPSD;PhosphoSitePlus	TCGA;ICGC	140.458	Down-regulation
CMGC_MAPK_JNK_MAPK9_ST	Q12968	NFATC3	P45984	MAPK9	S98	G101R	101	Missense	distal	3	no	154.151	154.467	EPSD	TCGA;ICGC;COSMIC	140.458	Up-regulation
CMGC_MAPK_JNK_MAPK9_ST	Q12968	NFATC3	P45984	MAPK9	S98	P103L	103	Missense	distal	5	no	154.151	154.920	EPSD	TCGA;ICGC	140.458	Up-regulation
CMGC_MAPK_JNK_MAPK9_ST	Q12968	NFATC3	P45984	MAPK9	S117	Q112R	112	Missense	distal	-5	no	151.515	151.531	EPSD	TCGA;ICGC;COSMIC	140.458	Up-regulation
CMGC_MAPK_JNK_MAPK9_ST	Q12968	NFATC3	P45984	MAPK9	S117	C120Y	120	Missense	distal	3	no	151.515	151.252	EPSD	TCGA;ICGC	140.458	Down-regulation
CMGC_MAPK_JNK_MAPK9_ST	Q12968	NFATC3	P45984	MAPK9	S117	Q112E	112	Missense	distal	-5	no	151.515	151.509	EPSD	TCGA;ICGC;COSMIC	140.458	Down-regulation
CMGC_MAPK_JNK_MAPK9_ST	Q12968	NFATC3	P45984	MAPK9	S117	S117C	117	Missense	central	0	yes	151.515	0.000	EPSD	TCGA;ICGC;COSMIC	140.458	Loss
CMGC_MAPK_JNK_MAPK9_ST	Q12968	NFATC3	P45984	MAPK9	S117	S110R	110	Missense	distal	-7	no	151.515	152.095	EPSD	TCGA;ICGC;COSMIC	140.458	Up-regulation
CMGC_MAPK_JNK_MAPK9_ST	Q12968	NFATC3	P45984	MAPK9	S177	F176L	176	Missense	proximal	-1	no	146.357	146.689	EPSD	TCGA;ICGC;COSMIC	140.458	Up-regulation
CMGC_MAPK_JNK_MAPK9_ST	Q12968	NFATC3	P45984	MAPK9	S177	D178N	178	Missense	proximal	1	no	146.357	-38.606	EPSD	TCGA;ICGC;COSMIC	140.458	Loss
CMGC_MAPK_JNK_MAPK9_ST	Q12968	NFATC3	P45984	MAPK9	S207	R202Q	202	Missense	distal	-5	no	152.556	152.540	EPSD	TCGA;ICGC;COSMIC	140.458	Down-regulation
CMGC_MAPK_JNK_MAPK9_ST	Q12968	NFATC3	P45984	MAPK9	S236	G232V	232	Missense	distal	-4	no	143.131	143.563	EPSD	TCGA;ICGC;COSMIC	140.458	Up-regulation
CMGC_MAPK_JNK_MAPK9_ST	Q12968	NFATC3	P45984	MAPK9	S236	H233Y	233	Missense	distal	-3	no	143.131	141.493	EPSD	TCGA;ICGC	140.458	Down-regulation
CMGC_MAPK_JNK_MAPK9_ST	Q12968	NFATC3	P45984	MAPK9	S240	P245S	245	Missense	distal	5	no	154.988	155.047	EPSD	TCGA;ICGC;COSMIC	140.458	Up-regulation
CMGC_MAPK_JNK_MAPK9_ST	Q12968	NFATC3	P45984	MAPK9	S240	H233Y	233	Missense	distal	-7	no	154.988	152.941	EPSD	TCGA;ICGC	140.458	Down-regulation
CMGC_MAPK_JNK_MAPK9_ST	Q12968	NFATC3	P45984	MAPK9	S244	P245S	245	Missense	proximal	1	no	144.008	-136.786	EPSD	TCGA;ICGC;COSMIC	140.458	Loss
CMGC_MAPK_JNK_MAPK9_ST	Q12968	NFATC3	P45984	MAPK9	S256	P259L	259	Missense	distal	3	no	156.857	156.549	EPSD	TCGA;ICGC;COSMIC	140.458	Down-regulation
CMGC_MAPK_JNK_MAPK9_ST	Q12968	NFATC3	P45984	MAPK9	S256	R258K	258	Missense	proximal	2	no	156.857	156.933	EPSD	TCGA;ICGC;COSMIC	140.458	Up-regulation
CMGC_MAPK_JNK_MAPK9_ST	Q12968	NFATC3	P45984	MAPK9	S269	R266T	266	Missense	distal	-3	no	162.521	160.968	EPSD	TCGA;ICGC;COSMIC	140.458	Down-regulation
CMGC_MAPK_JNK_MAPK9_ST	Q12968	NFATC3	P45984	MAPK9	S269	P270S	270	Missense	proximal	1	no	162.521	-118.273	EPSD	TCGA;ICGC;COSMIC	140.458	Loss
CMGC_MAPK_JNK_MAPK9_ST	Q12968	NFATC3	P45984	MAPK9	S269	R275M	275	Missense	distal	6	no	162.521	162.543	EPSD	TCGA;ICGC;COSMIC	140.458	Up-regulation
CMGC_MAPK_JNK_MAPK9_ST	Q12968	NFATC3	P45984	MAPK9	S288	P295L	295	Missense	distal	7	no	160.939	161.578	EPSD	TCGA;ICGC;COSMIC	140.458	Up-regulation
CMGC_MAPK_JNK_MAPK9_ST	Q12968	NFATC3	P45984	MAPK9	S292	S296L	296	Missense	distal	4	no	152.425	152.699	EPSD	TCGA;ICGC;COSMIC	140.458	Up-regulation
CMGC_MAPK_JNK_MAPK9_ST	Q12968	NFATC3	P45984	MAPK9	S292	P295L	295	Missense	distal	3	no	152.425	152.117	EPSD	TCGA;ICGC;COSMIC	140.458	Down-regulation
CMGC_MAPK_JNK_MAPK9_ST	Q12968	NFATC3	P45984	MAPK9	S296	S296L	296	Missense	central	0	yes	155.850	0.000	EPSD	TCGA;ICGC;COSMIC	140.458	Loss
CMGC_MAPK_JNK_MAPK9_ST	Q12968	NFATC3	P45984	MAPK9	S296	P295L	295	Missense	proximal	-1	no	155.850	155.694	EPSD	TCGA;ICGC;COSMIC	140.458	Down-regulation
CMGC_MAPK_JNK_MAPK9_ST	Q12968	NFATC3	P45984	MAPK9	S300	S296L	296	Missense	distal	-4	no	147.967	145.776	EPSD	TCGA;ICGC;COSMIC	140.458	Down-regulation
CMGC_MAPK_JNK_MAPK9_ST	Q12968	NFATC3	P45984	MAPK9	S300	P295L	295	Missense	distal	-5	no	147.967	148.066	EPSD	TCGA;ICGC;COSMIC	140.458	Up-regulation
CMGC_MAPK_JNK_MAPK9_ST	Q12968	NFATC3	P45984	MAPK9	S397	S397L	397	Missense	central	0	yes	150.482	0.000	EPSD	TCGA;ICGC;COSMIC	140.458	Loss
CMGC_MAPK_JNK_MAPK9_ST	Q12968	NFATC3	P45984	MAPK9	S397	P404L	404	Missense	distal	7	no	150.482	151.121	EPSD	TCGA;ICGC;COSMIC	140.458	Up-regulation
CMGC_MAPK_JNK_MAPK9_ST	Q12968	NFATC3	P45984	MAPK9	S397	P396H	396	Missense	proximal	-1	no	150.482	150.237	EPSD	TCGA;ICGC	140.458	Down-regulation
CMGC_MAPK_JNK_MAPK9_ST	Q12968	NFATC3	P45984	MAPK9	T409	S416L	416	Missense	distal	7	no	155.812	156.222	EPSD	TCGA;ICGC;COSMIC	140.458	Up-regulation
CMGC_MAPK_JNK_MAPK9_ST	Q12968	NFATC3	P45984	MAPK9	T409	P404L	404	Missense	distal	-5	no	155.812	155.911	EPSD	TCGA;ICGC;COSMIC	140.458	Up-regulation
CMGC_MAPK_JNK_MAPK9_ST	Q12968	NFATC3	P45984	MAPK9	S546	G539A	539	Missense	distal	-7	no	144.036	145.522	EPSD	TCGA;ICGC;COSMIC	140.458	Up-regulation
CMGC_MAPK_JNK_MAPK9_ST	Q12968	NFATC3	P45984	MAPK9	S731	S736L	736	Missense	distal	5	no	140.331	141.041	EPSD	TCGA;ICGC;COSMIC	140.458	Gain
CMGC_MAPK_JNK_MAPK9_ST	Q12968	NFATC3	P45984	MAPK9	S1063	P1064A	1064	Missense	proximal	1	no	160.786	142.142	EPSD	TCGA;ICGC;COSMIC	140.458	Down-regulation
CMGC_MAPK_JNK_MAPK9_ST	Q12968	NFATC3	P45984	MAPK9	S1063	P1060L	1060	Missense	distal	-3	no	160.786	159.213	EPSD	TCGA;ICGC;COSMIC	140.458	Down-regulation
CMGC_MAPK_JNK_MAPK9_ST	Q12968	NFATC3	P45984	MAPK9	S1063	E1065G	1065	Missense	proximal	2	no	160.786	160.917	EPSD	TCGA;ICGC	140.458	Up-regulation
CMGC_MAPK_JNK_MAPK9_ST	Q12968	NFATC3	P45984	MAPK9	S1072	E1065G	1065	Missense	distal	-7	no	141.347	140.079	EPSD	TCGA;ICGC	140.458	Loss
CMGC_MAPK_JNK_MAPK9_ST	P05412	JUN	P45984	MAPK9	S73	S73L	73	Missense	central	0	yes	158.505	0.000	PhosphoSitePlus;EPSD	TCGA;ICGC;COSMIC	140.458	Loss
CMGC_MAPK_JNK_MAPK9_ST	P05412	JUN	P45984	MAPK9	T91	G86W	86	Missense	distal	-5	no	158.955	159.033	EPSD	TCGA;ICGC;COSMIC	140.458	Up-regulation
CMGC_MAPK_JNK_MAPK9_ST	P05412	JUN	P45984	MAPK9	T93	G86W	86	Missense	distal	-7	no	155.827	153.148	EPSD	TCGA;ICGC;COSMIC	140.458	Down-regulation
CMGC_MAPK_JNK_MAPK9_ST	P05412	JUN	P45984	MAPK9	T93	C99Y	99	Missense	distal	6	no	155.827	155.483	EPSD	TCGA;ICGC;COSMIC	140.458	Down-regulation
CMGC_MAPK_JNK_MAPK9_ST	P05412	JUN	P45984	MAPK9	T239	P244L	244	Missense	distal	5	no	156.287	157.056	EPSD	TCGA;ICGC;COSMIC	140.458	Up-regulation
CMGC_MAPK_JNK_MAPK9_ST	P05412	JUN	P45984	MAPK9	S243	P244L	244	Missense	proximal	1	no	157.732	112.829	EPSD	TCGA;ICGC;COSMIC	140.458	Loss
CMGC_MAPK_JNK_MAPK9_ST	P05412	JUN	P45984	MAPK9	S296	Q290H	290	Missense	distal	-6	no	141.410	141.040	EPSD	TCGA;ICGC;COSMIC	140.458	Down-regulation
CMGC_MAPK_JNK_MAPK9_ST	P05412	JUN	P45984	MAPK9	S296	S296Y	296	Missense	central	0	yes	141.410	0.000	EPSD	TCGA;ICGC;COSMIC	140.458	Loss
CMGC_MAPK_JNK_MAPK9_ST	P04637	TP53	P45984	MAPK9	S20	P27S	27	Missense	distal	7	no	147.780	148.008	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	140.458	Up-regulation
CMGC_MAPK_JNK_MAPK9_ST	P04637	TP53	P45984	MAPK9	S20	P27L	27	Missense	distal	7	no	147.780	148.419	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC;GDSC;CCLE	140.458	Up-regulation
CMGC_MAPK_JNK_MAPK9_ST	P04637	TP53	P45984	MAPK9	S33	P27S	27	Missense	distal	-6	no	154.719	154.627	EPSD	TCGA;ICGC;COSMIC	140.458	Down-regulation
CMGC_MAPK_JNK_MAPK9_ST	P04637	TP53	P45984	MAPK9	S33	P27L	27	Missense	distal	-6	no	154.719	154.276	EPSD	TCGA;ICGC;COSMIC;GDSC;CCLE	140.458	Down-regulation
CMGC_MAPK_JNK_MAPK9_ST	P04637	TP53	P45984	MAPK9	S46	D48N	48	Missense	proximal	2	no	158.258	158.120	PhosphoSitePlus;EPSD	TCGA;ICGC;COSMIC;GDSC;CCLE	140.458	Down-regulation
CMGC_MAPK_JNK_MAPK9_ST	P04637	TP53	P45984	MAPK9	T81	A79V	79	Missense	proximal	-2	no	166.507	163.503	EPSD	TCGA;ICGC;COSMIC	140.458	Down-regulation
CMGC_MAPK_JNK_MAPK9_ST	P04637	TP53	P45984	MAPK9	T81	P77L	77	Missense	distal	-4	no	166.507	164.495	EPSD	TCGA;ICGC;COSMIC	140.458	Down-regulation
CMGC_MAPK_JNK_MAPK9_ST	P04637	TP53	P45984	MAPK9	T81	P82L	82	Missense	proximal	1	no	166.507	121.605	EPSD	TCGA;ICGC;COSMIC	140.458	Loss
CMGC_MAPK_JNK_MAPK9_ST	P04637	TP53	P45984	MAPK9	T81	A74T	74	Missense	distal	-7	no	166.507	163.964	EPSD	TCGA;ICGC;COSMIC	140.458	Down-regulation
CMGC_MAPK_JNK_MAPK9_ST	P04637	TP53	P45984	MAPK9	S99	G105C	105	Missense	distal	6	no	140.696	140.734	EPSD	TCGA;ICGC;COSMIC;GDSC	140.458	Up-regulation
CMGC_MAPK_JNK_MAPK9_ST	P04637	TP53	P45984	MAPK9	S99	S106R	106	Missense	distal	7	no	140.696	140.273	EPSD	TCGA;ICGC;COSMIC;GDSC;CCLE	140.458	Loss
CMGC_MAPK_JNK_MAPK9_ST	P04637	TP53	P45984	MAPK9	S99	G105R	105	Missense	distal	6	no	140.696	140.909	EPSD	TCGA;ICGC;COSMIC;CCLE	140.458	Up-regulation
CMGC_MAPK_JNK_MAPK9_ST	P04637	TP53	P45984	MAPK9	S99	G105V	105	Missense	distal	6	no	140.696	140.725	EPSD	TCGA;ICGC;COSMIC	140.458	Up-regulation
CMGC_MAPK_JNK_MAPK9_ST	P04637	TP53	P45984	MAPK9	S99	G105D	105	Missense	distal	6	no	140.696	140.710	EPSD	TCGA;ICGC;COSMIC	140.458	Up-regulation
CMGC_MAPK_JNK_MAPK9_ST	P04637	TP53	P45984	MAPK9	S99	G105S	105	Missense	distal	6	no	140.696	140.872	EPSD	TCGA;ICGC;COSMIC	140.458	Up-regulation
CMGC_MAPK_JNK_MAPK9_ST	P04637	TP53	P45984	MAPK9	S99	V97D	97	Missense	proximal	-2	no	140.696	141.179	EPSD	TCGA;ICGC;COSMIC	140.458	Up-regulation
CMGC_MAPK_JNK_MAPK9_ST	P04637	TP53	P45984	MAPK9	S99	P92S	92	Missense	distal	-7	no	140.696	141.727	EPSD	TCGA;ICGC	140.458	Up-regulation
CMGC_MAPK_JNK_MAPK9_ST	P04637	TP53	P45984	MAPK9	S127	K132N	132	Missense	distal	5	no	145.026	144.628	EPSD	TCGA;ICGC;COSMIC;GDSC;CCLE	140.458	Down-regulation
CMGC_MAPK_JNK_MAPK9_ST	P04637	TP53	P45984	MAPK9	S127	S121Y	121	Missense	distal	-6	no	145.026	144.347	EPSD	TCGA;ICGC;COSMIC	140.458	Down-regulation
CMGC_MAPK_JNK_MAPK9_ST	P04637	TP53	P45984	MAPK9	S127	M133K	133	Missense	distal	6	no	145.026	144.925	EPSD	TCGA;ICGC;COSMIC;CCLE	140.458	Down-regulation
CMGC_MAPK_JNK_MAPK9_ST	P04637	TP53	P45984	MAPK9	S127	K132E	132	Missense	distal	5	no	145.026	144.882	EPSD	TCGA;ICGC;COSMIC;GDSC;CCLE	140.458	Down-regulation
CMGC_MAPK_JNK_MAPK9_ST	P04637	TP53	P45984	MAPK9	S127	Y126C	126	Missense	proximal	-1	no	145.026	145.304	EPSD	TCGA;ICGC;COSMIC;GDSC	140.458	Up-regulation
CMGC_MAPK_JNK_MAPK9_ST	P04637	TP53	P45984	MAPK9	S127	S127P	127	Missense	central	0	yes	145.026	0.000	EPSD	TCGA;ICGC;COSMIC;GDSC;CCLE	140.458	Loss
CMGC_MAPK_JNK_MAPK9_ST	P04637	TP53	P45984	MAPK9	S127	Y126N	126	Missense	proximal	-1	no	145.026	145.521	EPSD	TCGA;ICGC;COSMIC	140.458	Up-regulation
CMGC_MAPK_JNK_MAPK9_ST	P04637	TP53	P45984	MAPK9	S127	L130V	130	Missense	distal	3	no	145.026	145.210	EPSD	TCGA;ICGC;COSMIC;GDSC;CCLE	140.458	Up-regulation
CMGC_MAPK_JNK_MAPK9_ST	P04637	TP53	P45984	MAPK9	S127	K132T	132	Missense	distal	5	no	145.026	145.248	EPSD	TCGA;ICGC;COSMIC;GDSC;CCLE	140.458	Up-regulation
CMGC_MAPK_JNK_MAPK9_ST	P04637	TP53	P45984	MAPK9	S127	S127Y	127	Missense	central	0	yes	145.026	0.000	EPSD	TCGA;ICGC;COSMIC	140.458	Loss
CMGC_MAPK_JNK_MAPK9_ST	P04637	TP53	P45984	MAPK9	S127	S127F	127	Missense	central	0	yes	145.026	0.000	EPSD	TCGA;ICGC;COSMIC;CCLE	140.458	Loss
CMGC_MAPK_JNK_MAPK9_ST	P04637	TP53	P45984	MAPK9	S127	M133R	133	Missense	distal	6	no	145.026	145.003	EPSD	TCGA;ICGC;COSMIC	140.458	Down-regulation
CMGC_MAPK_JNK_MAPK9_ST	P04637	TP53	P45984	MAPK9	S127	K132R	132	Missense	distal	5	no	145.026	144.626	EPSD	TCGA;ICGC;COSMIC;GDSC;CCLE	140.458	Down-regulation
CMGC_MAPK_JNK_MAPK9_ST	P04637	TP53	P45984	MAPK9	S127	F134L	134	Missense	distal	7	no	145.026	144.641	EPSD	TCGA;ICGC;COSMIC;CCLE	140.458	Down-regulation
CMGC_MAPK_JNK_MAPK9_ST	P04637	TP53	P45984	MAPK9	S127	Y126S	126	Missense	proximal	-1	no	145.026	145.350	EPSD	TCGA;ICGC;COSMIC	140.458	Up-regulation
CMGC_MAPK_JNK_MAPK9_ST	P04637	TP53	P45984	MAPK9	S127	L130P	130	Missense	distal	3	no	145.026	145.334	EPSD	TCGA;ICGC;COSMIC	140.458	Up-regulation
CMGC_MAPK_JNK_MAPK9_ST	P04637	TP53	P45984	MAPK9	S127	L130F	130	Missense	distal	3	no	145.026	144.934	EPSD	TCGA;ICGC;COSMIC;CCLE	140.458	Down-regulation
CMGC_MAPK_JNK_MAPK9_ST	P04637	TP53	P45984	MAPK9	S127	F134V	134	Missense	distal	7	no	145.026	144.599	EPSD	TCGA;ICGC;COSMIC	140.458	Down-regulation
CMGC_MAPK_JNK_MAPK9_ST	P04637	TP53	P45984	MAPK9	S127	T125M	125	Missense	proximal	-2	no	145.026	146.794	EPSD	TCGA;ICGC;COSMIC;GDSC	140.458	Up-regulation
CMGC_MAPK_JNK_MAPK9_ST	P04637	TP53	P45984	MAPK9	S127	Y126D	126	Missense	proximal	-1	no	145.026	145.209	EPSD	TCGA;ICGC;COSMIC;GDSC	140.458	Up-regulation
CMGC_MAPK_JNK_MAPK9_ST	P04637	TP53	P45984	MAPK9	S127	K120E	120	Missense	distal	-7	no	145.026	145.477	EPSD	TCGA;ICGC;COSMIC	140.458	Up-regulation
CMGC_MAPK_JNK_MAPK9_ST	P04637	TP53	P45984	MAPK9	S127	N131S	131	Missense	distal	4	no	145.026	145.059	EPSD	TCGA;ICGC;COSMIC	140.458	Up-regulation
CMGC_MAPK_JNK_MAPK9_ST	P04637	TP53	P45984	MAPK9	S127	T125P	125	Missense	proximal	-2	no	145.026	148.662	EPSD	TCGA;ICGC;COSMIC;CCLE	140.458	Up-regulation
CMGC_MAPK_JNK_MAPK9_ST	P04637	TP53	P45984	MAPK9	S127	S127C	127	Missense	central	0	yes	145.026	0.000	EPSD	TCGA;ICGC;COSMIC;CCLE	140.458	Loss
CMGC_MAPK_JNK_MAPK9_ST	P04637	TP53	P45984	MAPK9	S127	N131I	131	Missense	distal	4	no	145.026	145.250	EPSD	TCGA;ICGC;COSMIC	140.458	Up-regulation
CMGC_MAPK_JNK_MAPK9_ST	P04637	TP53	P45984	MAPK9	S127	Y126H	126	Missense	proximal	-1	no	145.026	145.218	EPSD	TCGA;ICGC;COSMIC;GDSC	140.458	Up-regulation
CMGC_MAPK_JNK_MAPK9_ST	P04637	TP53	P45984	MAPK9	S127	K132Q	132	Missense	distal	5	no	145.026	144.835	EPSD	TCGA;ICGC;COSMIC;GDSC;CCLE	140.458	Down-regulation
CMGC_MAPK_JNK_MAPK9_ST	P04637	TP53	P45984	MAPK9	S127	L130R	130	Missense	distal	3	no	145.026	145.443	EPSD	TCGA;ICGC;COSMIC;CCLE	140.458	Up-regulation
CMGC_MAPK_JNK_MAPK9_ST	P04637	TP53	P45984	MAPK9	T150	W146S	146	Missense	distal	-4	no	153.234	156.863	EPSD	TCGA;ICGC;COSMIC	140.458	Up-regulation
CMGC_MAPK_JNK_MAPK9_ST	P04637	TP53	P45984	MAPK9	T150	P152L	152	Missense	proximal	2	no	153.234	153.389	EPSD	TCGA;ICGC;COSMIC;GDSC;CCLE	140.458	Up-regulation
CMGC_MAPK_JNK_MAPK9_ST	P04637	TP53	P45984	MAPK9	T150	D148N	148	Missense	proximal	-2	no	153.234	154.378	EPSD	TCGA;ICGC;COSMIC	140.458	Up-regulation
CMGC_MAPK_JNK_MAPK9_ST	P04637	TP53	P45984	MAPK9	T150	P151H	151	Missense	proximal	1	no	153.234	-6.872	EPSD	TCGA;ICGC;COSMIC;GDSC;CCLE	140.458	Loss
CMGC_MAPK_JNK_MAPK9_ST	P04637	TP53	P45984	MAPK9	T150	P151A	151	Missense	proximal	1	no	153.234	134.590	EPSD	TCGA;ICGC;COSMIC;CCLE	140.458	Loss
CMGC_MAPK_JNK_MAPK9_ST	P04637	TP53	P45984	MAPK9	T150	R156P	156	Missense	distal	6	no	153.234	153.170	EPSD	TCGA;ICGC;COSMIC;GDSC;CCLE	140.458	Down-regulation
CMGC_MAPK_JNK_MAPK9_ST	P04637	TP53	P45984	MAPK9	T150	V143A	143	Missense	distal	-7	no	153.234	155.315	EPSD	TCGA;ICGC;COSMIC;GDSC;CCLE	140.458	Up-regulation
CMGC_MAPK_JNK_MAPK9_ST	P04637	TP53	P45984	MAPK9	T150	P151S	151	Missense	proximal	1	no	153.234	-127.560	EPSD	TCGA;ICGC;COSMIC;GDSC;CCLE	140.458	Loss
CMGC_MAPK_JNK_MAPK9_ST	P04637	TP53	P45984	MAPK9	T150	V157F	157	Missense	distal	7	no	153.234	153.660	EPSD	TCGA;ICGC;COSMIC;GDSC;CCLE	140.458	Up-regulation
CMGC_MAPK_JNK_MAPK9_ST	P04637	TP53	P45984	MAPK9	T150	V157G	157	Missense	distal	7	no	153.234	153.191	EPSD	TCGA;ICGC;COSMIC	140.458	Down-regulation
CMGC_MAPK_JNK_MAPK9_ST	P04637	TP53	P45984	MAPK9	T150	V157D	157	Missense	distal	7	no	153.234	153.407	EPSD	TCGA;ICGC;COSMIC	140.458	Up-regulation
CMGC_MAPK_JNK_MAPK9_ST	P04637	TP53	P45984	MAPK9	T150	L145R	145	Missense	distal	-5	no	153.234	153.126	EPSD	TCGA;ICGC;COSMIC;GDSC;CCLE	140.458	Down-regulation
CMGC_MAPK_JNK_MAPK9_ST	P04637	TP53	P45984	MAPK9	T150	T155I	155	Missense	distal	5	no	153.234	153.490	EPSD	TCGA;ICGC;COSMIC;CCLE	140.458	Up-regulation
CMGC_MAPK_JNK_MAPK9_ST	P04637	TP53	P45984	MAPK9	T150	V143M	143	Missense	distal	-7	no	153.234	154.551	EPSD	TCGA;ICGC;COSMIC;GDSC;CCLE	140.458	Up-regulation
CMGC_MAPK_JNK_MAPK9_ST	P04637	TP53	P45984	MAPK9	T150	T155N	155	Missense	distal	5	no	153.234	152.614	EPSD	TCGA;ICGC;COSMIC;GDSC;CCLE	140.458	Down-regulation
CMGC_MAPK_JNK_MAPK9_ST	P04637	TP53	P45984	MAPK9	T150	P152S	152	Missense	proximal	2	no	153.234	153.329	EPSD	TCGA;ICGC;COSMIC;CCLE	140.458	Up-regulation
CMGC_MAPK_JNK_MAPK9_ST	P04637	TP53	P45984	MAPK9	T150	R156C	156	Missense	distal	6	no	153.234	153.060	EPSD	TCGA;ICGC;COSMIC	140.458	Down-regulation
CMGC_MAPK_JNK_MAPK9_ST	P04637	TP53	P45984	MAPK9	T150	P151T	151	Missense	proximal	1	no	153.234	134.038	EPSD	TCGA;ICGC;COSMIC	140.458	Loss
CMGC_MAPK_JNK_MAPK9_ST	P04637	TP53	P45984	MAPK9	T150	T155P	155	Missense	distal	5	no	153.234	152.785	EPSD	TCGA;ICGC;COSMIC;CCLE	140.458	Down-regulation
CMGC_MAPK_JNK_MAPK9_ST	P04637	TP53	P45984	MAPK9	T150	V143G	143	Missense	distal	-7	no	153.234	153.829	EPSD	TCGA;ICGC;COSMIC	140.458	Up-regulation
CMGC_MAPK_JNK_MAPK9_ST	P04637	TP53	P45984	MAPK9	T150	P152Q	152	Missense	proximal	2	no	153.234	153.253	EPSD	TCGA;ICGC;COSMIC	140.458	Up-regulation
CMGC_MAPK_JNK_MAPK9_ST	P04637	TP53	P45984	MAPK9	T150	R156H	156	Missense	distal	6	no	153.234	152.943	EPSD	TCGA;ICGC;COSMIC	140.458	Down-regulation
CMGC_MAPK_JNK_MAPK9_ST	P04637	TP53	P45984	MAPK9	T150	L145P	145	Missense	distal	-5	no	153.234	153.134	EPSD	TCGA;ICGC;COSMIC	140.458	Down-regulation
CMGC_MAPK_JNK_MAPK9_ST	P04637	TP53	P45984	MAPK9	T150	Q144L	144	Missense	distal	-6	no	153.234	152.752	EPSD	TCGA;ICGC;COSMIC	140.458	Down-regulation
CMGC_MAPK_JNK_MAPK9_ST	P04637	TP53	P45984	MAPK9	T150	Q144H	144	Missense	distal	-6	no	153.234	152.865	EPSD	TCGA;ICGC;COSMIC	140.458	Down-regulation
CMGC_MAPK_JNK_MAPK9_ST	P04637	TP53	P45984	MAPK9	T150	G154V	154	Missense	distal	4	no	153.234	153.177	EPSD	TCGA;ICGC;COSMIC;GDSC;CCLE	140.458	Down-regulation
CMGC_MAPK_JNK_MAPK9_ST	P04637	TP53	P45984	MAPK9	T150	V157L	157	Missense	distal	7	no	153.234	153.275	EPSD	TCGA;ICGC;COSMIC	140.458	Up-regulation
CMGC_MAPK_JNK_MAPK9_ST	P04637	TP53	P45984	MAPK9	T150	P151R	151	Missense	proximal	1	no	153.234	115.646	EPSD	TCGA;ICGC;COSMIC	140.458	Loss
CMGC_MAPK_JNK_MAPK9_ST	P04637	TP53	P45984	MAPK9	T150	Q144P	144	Missense	distal	-6	no	153.234	153.194	EPSD	TCGA;ICGC;COSMIC	140.458	Down-regulation
CMGC_MAPK_JNK_MAPK9_ST	P04637	TP53	P45984	MAPK9	T150	V143E	143	Missense	distal	-7	no	153.234	155.096	EPSD	TCGA;ICGC;COSMIC	140.458	Up-regulation
CMGC_MAPK_JNK_MAPK9_ST	P04637	TP53	P45984	MAPK9	T150	R156G	156	Missense	distal	6	no	153.234	153.021	EPSD	TCGA;ICGC;COSMIC	140.458	Down-regulation
CMGC_MAPK_JNK_MAPK9_ST	P04637	TP53	P45984	MAPK9	T150	P151L	151	Missense	proximal	1	no	153.234	108.331	EPSD	TCGA;ICGC;COSMIC	140.458	Loss
CMGC_MAPK_JNK_MAPK9_ST	P04637	TP53	P45984	MAPK9	T155	R156P	156	Missense	proximal	1	no	114.543	152.131	EPSD	TCGA;ICGC;COSMIC;GDSC;CCLE	140.458	Gain
CMGC_MAPK_JNK_MAPK9_ST	P04637	TP53	P45984	MAPK9	S183	H179R	179	Missense	distal	-4	no	144.606	146.246	EPSD	TCGA;ICGC;COSMIC;GDSC;CCLE	140.458	Up-regulation
CMGC_MAPK_JNK_MAPK9_ST	P04637	TP53	P45984	MAPK9	S183	C176F	176	Missense	distal	-7	no	144.606	142.941	EPSD	TCGA;ICGC;COSMIC;GDSC;CCLE	140.458	Down-regulation
CMGC_MAPK_JNK_MAPK9_ST	P04637	TP53	P45984	MAPK9	S183	R181H	181	Missense	proximal	-2	no	144.606	141.780	EPSD	TCGA;ICGC;COSMIC;CCLE	140.458	Down-regulation
CMGC_MAPK_JNK_MAPK9_ST	P04637	TP53	P45984	MAPK9	S183	G187S	187	Missense	distal	4	no	144.606	144.399	EPSD	TCGA;ICGC;COSMIC	140.458	Down-regulation
CMGC_MAPK_JNK_MAPK9_ST	P04637	TP53	P45984	MAPK9	S183	H179Y	179	Missense	distal	-4	no	144.606	143.537	EPSD	TCGA;ICGC;COSMIC	140.458	Down-regulation
CMGC_MAPK_JNK_MAPK9_ST	P04637	TP53	P45984	MAPK9	S183	C176Y	176	Missense	distal	-7	no	144.606	142.668	EPSD	TCGA;ICGC;COSMIC;GDSC;CCLE	140.458	Down-regulation
CMGC_MAPK_JNK_MAPK9_ST	P04637	TP53	P45984	MAPK9	S183	P190L	190	Missense	distal	7	no	144.606	145.246	EPSD	TCGA;ICGC;COSMIC;CCLE	140.458	Up-regulation
CMGC_MAPK_JNK_MAPK9_ST	P04637	TP53	P45984	MAPK9	S183	P177S	177	Missense	distal	-6	no	144.606	144.515	EPSD	TCGA;ICGC;COSMIC	140.458	Down-regulation
CMGC_MAPK_JNK_MAPK9_ST	P04637	TP53	P45984	MAPK9	S183	H178Q	178	Missense	distal	-5	no	144.606	144.534	EPSD	TCGA;ICGC;COSMIC	140.458	Down-regulation
CMGC_MAPK_JNK_MAPK9_ST	P04637	TP53	P45984	MAPK9	S183	E180K	180	Missense	distal	-3	no	144.606	143.332	EPSD	TCGA;ICGC;COSMIC;CCLE	140.458	Down-regulation
CMGC_MAPK_JNK_MAPK9_ST	P04637	TP53	P45984	MAPK9	S183	C176S	176	Missense	distal	-7	no	144.606	145.880	EPSD	TCGA;ICGC;COSMIC;GDSC;CCLE	140.458	Up-regulation
CMGC_MAPK_JNK_MAPK9_ST	P04637	TP53	P45984	MAPK9	S183	H179N	179	Missense	distal	-4	no	144.606	147.863	EPSD	TCGA;ICGC;COSMIC	140.458	Up-regulation
CMGC_MAPK_JNK_MAPK9_ST	P04637	TP53	P45984	MAPK9	S183	H179P	179	Missense	distal	-4	no	144.606	146.366	EPSD	TCGA;ICGC;COSMIC	140.458	Up-regulation
CMGC_MAPK_JNK_MAPK9_ST	P04637	TP53	P45984	MAPK9	S183	H179L	179	Missense	distal	-4	no	144.606	144.354	EPSD	TCGA;ICGC;COSMIC	140.458	Down-regulation
CMGC_MAPK_JNK_MAPK9_ST	P04637	TP53	P45984	MAPK9	S183	H179D	179	Missense	distal	-4	no	144.606	145.842	EPSD	TCGA;ICGC;COSMIC;GDSC;CCLE	140.458	Up-regulation
CMGC_MAPK_JNK_MAPK9_ST	P04637	TP53	P45984	MAPK9	S183	P190R	190	Missense	distal	7	no	144.606	144.412	EPSD	TCGA;ICGC;COSMIC	140.458	Down-regulation
CMGC_MAPK_JNK_MAPK9_ST	P04637	TP53	P45984	MAPK9	S183	P177R	177	Missense	distal	-6	no	144.606	144.718	EPSD	TCGA;ICGC;COSMIC	140.458	Up-regulation
CMGC_MAPK_JNK_MAPK9_ST	P04637	TP53	P45984	MAPK9	S183	P177H	177	Missense	distal	-6	no	144.606	144.277	EPSD	TCGA;ICGC;COSMIC	140.458	Down-regulation
CMGC_MAPK_JNK_MAPK9_ST	P04637	TP53	P45984	MAPK9	S183	C176W	176	Missense	distal	-7	no	144.606	142.835	EPSD	TCGA;ICGC;COSMIC;GDSC;CCLE	140.458	Down-regulation
CMGC_MAPK_JNK_MAPK9_ST	P04637	TP53	P45984	MAPK9	S183	H179Q	179	Missense	distal	-4	no	144.606	147.677	EPSD	TCGA;ICGC;COSMIC;GDSC;CCLE	140.458	Up-regulation
CMGC_MAPK_JNK_MAPK9_ST	P04637	TP53	P45984	MAPK9	S183	P177T	177	Missense	distal	-6	no	144.606	144.247	EPSD	TCGA;ICGC;COSMIC;GDSC;CCLE	140.458	Down-regulation
CMGC_MAPK_JNK_MAPK9_ST	P04637	TP53	P45984	MAPK9	S183	R181P	181	Missense	proximal	-2	no	144.606	145.810	EPSD	TCGA;ICGC;COSMIC;CCLE	140.458	Up-regulation
CMGC_MAPK_JNK_MAPK9_ST	P04637	TP53	P45984	MAPK9	S183	C176R	176	Missense	distal	-7	no	144.606	146.460	EPSD	TCGA;ICGC;COSMIC	140.458	Up-regulation
CMGC_MAPK_JNK_MAPK9_ST	P04637	TP53	P45984	MAPK9	S183	R181C	181	Missense	proximal	-2	no	144.606	142.838	EPSD	TCGA;ICGC;COSMIC;GDSC;CCLE	140.458	Down-regulation
CMGC_MAPK_JNK_MAPK9_ST	P04637	TP53	P45984	MAPK9	S183	P177L	177	Missense	distal	-6	no	144.606	144.164	EPSD	TCGA;ICGC;COSMIC;GDSC;CCLE	140.458	Down-regulation
CMGC_MAPK_JNK_MAPK9_ST	P04637	TP53	P45984	MAPK9	S315	K319N	319	Missense	distal	4	no	155.450	155.401	EPSD	TCGA;ICGC;COSMIC	140.458	Down-regulation
CMGC_MAPK_JNK_MAPK9_ST	P04637	TP53	P45984	MAPK9	S315	K320E	320	Missense	distal	5	no	155.450	155.306	EPSD	TCGA;ICGC;COSMIC	140.458	Down-regulation
CMGC_MAPK_JNK_MAPK9_ST	P04637	TP53	P45984	MAPK9	S315	S315C	315	Missense	central	0	yes	155.450	0.000	EPSD	TCGA;ICGC;COSMIC	140.458	Loss
CMGC_MAPK_JNK_MAPK9_ST	Q9UIG0	BAZ1B	P45984	MAPK9	S46	I49N	49	Missense	distal	3	no	142.052	142.296	EPSD	TCGA;ICGC;COSMIC	140.458	Up-regulation
CMGC_MAPK_JNK_MAPK9_ST	Q9UIG0	BAZ1B	P45984	MAPK9	S46	R48C	48	Missense	proximal	2	no	142.052	142.206	EPSD	TCGA;ICGC;COSMIC	140.458	Up-regulation
CMGC_MAPK_JNK_MAPK9_ST	Q9UIG0	BAZ1B	P45984	MAPK9	S46	E43K	43	Missense	distal	-3	no	142.052	140.778	EPSD	TCGA;ICGC;COSMIC	140.458	Down-regulation
CMGC_MAPK_JNK_MAPK9_ST	Q9UIG0	BAZ1B	P45984	MAPK9	S158	E164D	164	Missense	distal	6	no	159.645	159.370	PhosphoSitePlus	TCGA;ICGC	140.458	Down-regulation
CMGC_MAPK_JNK_MAPK9_ST	Q9UIG0	BAZ1B	P45984	MAPK9	S161	S166Y	166	Missense	distal	5	no	143.487	144.608	EPSD	TCGA	140.458	Up-regulation
CMGC_MAPK_JNK_MAPK9_ST	Q9UIG0	BAZ1B	P45984	MAPK9	S161	Q168E	168	Missense	distal	7	no	143.487	143.529	EPSD	TCGA;ICGC;COSMIC	140.458	Up-regulation
CMGC_MAPK_JNK_MAPK9_ST	Q9UIG0	BAZ1B	P45984	MAPK9	S161	E164D	164	Missense	distal	3	no	143.487	143.339	EPSD	TCGA;ICGC	140.458	Down-regulation
CMGC_MAPK_JNK_MAPK9_ST	Q9UIG0	BAZ1B	P45984	MAPK9	S197	S204L	204	Missense	distal	7	no	161.590	162.001	EPSD	TCGA;ICGC;COSMIC	140.458	Up-regulation
CMGC_MAPK_JNK_MAPK9_ST	Q9UIG0	BAZ1B	P45984	MAPK9	S197	R199Q	199	Missense	proximal	2	no	161.590	161.635	EPSD	TCGA;ICGC;COSMIC	140.458	Up-regulation
CMGC_MAPK_JNK_MAPK9_ST	Q9UIG0	BAZ1B	P45984	MAPK9	S197	P202R	202	Missense	distal	5	no	161.590	161.417	EPSD	TCGA;ICGC;COSMIC	140.458	Down-regulation
CMGC_MAPK_JNK_MAPK9_ST	Q9UIG0	BAZ1B	P45984	MAPK9	S197	R195H	195	Missense	proximal	-2	no	161.590	158.763	EPSD	TCGA;ICGC	140.458	Down-regulation
CMGC_MAPK_JNK_MAPK9_ST	Q9UIG0	BAZ1B	P45984	MAPK9	S197	D192N	192	Missense	distal	-5	no	161.590	161.472	EPSD	TCGA	140.458	Down-regulation
CMGC_MAPK_JNK_MAPK9_ST	Q9UIG0	BAZ1B	P45984	MAPK9	S312	T310S	310	Missense	proximal	-2	no	150.992	150.868	EPSD	TCGA;ICGC;COSMIC	140.458	Down-regulation
CMGC_MAPK_JNK_MAPK9_ST	Q9UIG0	BAZ1B	P45984	MAPK9	S349	L342F	342	Missense	distal	-7	no	148.899	148.119	EPSD	TCGA;ICGC;COSMIC	140.458	Down-regulation
CMGC_MAPK_JNK_MAPK9_ST	Q9UIG0	BAZ1B	P45984	MAPK9	S349	G348D	348	Missense	proximal	-1	no	148.899	148.820	EPSD	TCGA;ICGC	140.458	Down-regulation
CMGC_MAPK_JNK_MAPK9_ST	Q9UIG0	BAZ1B	P45984	MAPK9	S361	P362H	362	Missense	proximal	1	no	152.171	-7.935	EPSD	TCGA;ICGC;COSMIC	140.458	Loss
CMGC_MAPK_JNK_MAPK9_ST	Q9UIG0	BAZ1B	P45984	MAPK9	S361	E364Q	364	Missense	distal	3	no	152.171	152.266	EPSD	TCGA;ICGC;COSMIC	140.458	Up-regulation
CMGC_MAPK_JNK_MAPK9_ST	Q9UIG0	BAZ1B	P45984	MAPK9	S361	P362S	362	Missense	proximal	1	no	152.171	-128.623	EPSD	TCGA;ICGC;COSMIC	140.458	Loss
CMGC_MAPK_JNK_MAPK9_ST	Q9UIG0	BAZ1B	P45984	MAPK9	S374	H379Q	379	Missense	distal	5	no	159.930	159.389	EPSD	TCGA;ICGC;COSMIC	140.458	Down-regulation
CMGC_MAPK_JNK_MAPK9_ST	Q9UIG0	BAZ1B	P45984	MAPK9	S374	M372I	372	Missense	proximal	-2	no	159.930	158.662	EPSD	TCGA;ICGC;COSMIC	140.458	Down-regulation
CMGC_MAPK_JNK_MAPK9_ST	Q9UIG0	BAZ1B	P45984	MAPK9	S374	N376D	376	Missense	proximal	2	no	159.930	160.068	EPSD	TCGA;ICGC;COSMIC	140.458	Up-regulation
CMGC_MAPK_JNK_MAPK9_ST	Q9UIG0	BAZ1B	P45984	MAPK9	S374	P375S	375	Missense	proximal	1	no	159.930	-120.864	EPSD	TCGA;ICGC;COSMIC	140.458	Loss
CMGC_MAPK_JNK_MAPK9_ST	Q9UIG0	BAZ1B	P45984	MAPK9	S374	S374L	374	Missense	central	0	yes	159.930	0.000	EPSD	TCGA;ICGC;COSMIC	140.458	Loss
CMGC_MAPK_JNK_MAPK9_ST	Q9UIG0	BAZ1B	P45984	MAPK9	S423	L428P	428	Missense	distal	5	no	150.878	150.109	EPSD	TCGA;ICGC;COSMIC	140.458	Down-regulation
CMGC_MAPK_JNK_MAPK9_ST	Q9UIG0	BAZ1B	P45984	MAPK9	S423	S417F	417	Missense	distal	-6	no	150.878	150.179	EPSD	TCGA;ICGC;COSMIC	140.458	Down-regulation
CMGC_MAPK_JNK_MAPK9_ST	Q9UIG0	BAZ1B	P45984	MAPK9	T430	L428P	428	Missense	proximal	-2	no	156.033	157.108	EPSD	TCGA;ICGC;COSMIC	140.458	Up-regulation
CMGC_MAPK_JNK_MAPK9_ST	Q9UIG0	BAZ1B	P45984	MAPK9	T430	P431S	431	Missense	proximal	1	no	156.033	-124.761	EPSD	TCGA;ICGC;COSMIC	140.458	Loss
CMGC_MAPK_JNK_MAPK9_ST	Q9UIG0	BAZ1B	P45984	MAPK9	T460	R455Q	455	Missense	distal	-5	no	154.003	153.986	EPSD	TCGA;ICGC	140.458	Down-regulation
CMGC_MAPK_JNK_MAPK9_ST	Q9UIG0	BAZ1B	P45984	MAPK9	T460	T460A	460	Missense	central	0	yes	154.003	0.000	EPSD	TCGA;ICGC;COSMIC;GDSC;CCLE	140.458	Loss
CMGC_MAPK_JNK_MAPK9_ST	Q9UIG0	BAZ1B	P45984	MAPK9	T460	G459D	459	Missense	proximal	-1	no	154.003	153.924	EPSD	TCGA;ICGC;COSMIC	140.458	Down-regulation
CMGC_MAPK_JNK_MAPK9_ST	Q9UIG0	BAZ1B	P45984	MAPK9	S699	E703V	703	Missense	distal	4	no	146.550	146.783	EPSD	TCGA;ICGC;COSMIC	140.458	Up-regulation
CMGC_MAPK_JNK_MAPK9_ST	Q9UIG0	BAZ1B	P45984	MAPK9	S699	R697C	697	Missense	proximal	-2	no	146.550	144.782	EPSD	TCGA;ICGC;COSMIC	140.458	Down-regulation
CMGC_MAPK_JNK_MAPK9_ST	Q9UIG0	BAZ1B	P45984	MAPK9	S699	R693W	693	Missense	distal	-6	no	146.550	145.745	EPSD	TCGA;ICGC;COSMIC	140.458	Down-regulation
CMGC_MAPK_JNK_MAPK9_ST	Q9UIG0	BAZ1B	P45984	MAPK9	S708	E703V	703	Missense	distal	-5	no	145.957	146.040	EPSD	TCGA;ICGC;COSMIC	140.458	Up-regulation
CMGC_MAPK_JNK_MAPK9_ST	Q9UIG0	BAZ1B	P45984	MAPK9	S708	K714T	714	Missense	distal	6	no	145.957	145.722	EPSD	TCGA;ICGC	140.458	Down-regulation
CMGC_MAPK_JNK_MAPK9_ST	Q9UIG0	BAZ1B	P45984	MAPK9	S716	D721E	721	Missense	distal	5	no	141.426	140.885	EPSD	TCGA;ICGC;COSMIC	140.458	Down-regulation
CMGC_MAPK_JNK_MAPK9_ST	Q9UIG0	BAZ1B	P45984	MAPK9	S716	K714T	714	Missense	proximal	-2	no	141.426	141.660	EPSD	TCGA;ICGC	140.458	Up-regulation
CMGC_MAPK_JNK_MAPK9_ST	Q9UIG0	BAZ1B	P45984	MAPK9	T983	V977I	977	Missense	distal	-6	no	157.929	157.926	EPSD	TCGA;ICGC;COSMIC	140.458	Down-regulation
CMGC_MAPK_JNK_MAPK9_ST	Q9UIG0	BAZ1B	P45984	MAPK9	S1249	G1242D	1242	Missense	distal	-7	no	141.448	141.282	EPSD	TCGA;ICGC;COSMIC	140.458	Down-regulation
CMGC_MAPK_JNK_MAPK9_ST	P30307	CDC25C	P45984	MAPK9	T67	D73N	73	Missense	distal	6	no	149.859	150.324	EPSD	TCGA;ICGC;COSMIC	140.458	Up-regulation
CMGC_MAPK_JNK_MAPK9_ST	P30307	CDC25C	P45984	MAPK9	S122	L127I	127	Missense	distal	5	no	153.441	153.377	EPSD	TCGA;ICGC	140.458	Down-regulation
CMGC_MAPK_JNK_MAPK9_ST	P30307	CDC25C	P45984	MAPK9	S122	L127V	127	Missense	distal	5	no	153.441	153.159	EPSD	TCGA;ICGC;COSMIC	140.458	Down-regulation
CMGC_MAPK_JNK_MAPK9_ST	P30307	CDC25C	P45984	MAPK9	S129	L127I	127	Missense	proximal	-2	no	142.814	140.751	EPSD	TCGA;ICGC	140.458	Down-regulation
CMGC_MAPK_JNK_MAPK9_ST	P30307	CDC25C	P45984	MAPK9	S129	L127V	127	Missense	proximal	-2	no	142.814	139.613	EPSD	TCGA;ICGC;COSMIC	140.458	Loss
CMGC_MAPK_JNK_MAPK9_ST	P30307	CDC25C	P45984	MAPK9	T130	G137C	137	Missense	distal	7	no	150.521	150.445	EPSD	TCGA;ICGC	140.458	Down-regulation
CMGC_MAPK_JNK_MAPK9_ST	P30307	CDC25C	P45984	MAPK9	T130	L127I	127	Missense	distal	-3	no	150.521	149.667	EPSD	TCGA;ICGC	140.458	Down-regulation
CMGC_MAPK_JNK_MAPK9_ST	P30307	CDC25C	P45984	MAPK9	T130	L127V	127	Missense	distal	-3	no	150.521	150.004	EPSD	TCGA;ICGC;COSMIC	140.458	Down-regulation
CMGC_MAPK_JNK_MAPK9_ST	P30307	CDC25C	P45984	MAPK9	S191	E188D	188	Missense	distal	-3	no	140.501	139.711	EPSD	TCGA;ICGC	140.458	Loss
CMGC_MAPK_JNK_MAPK9_ST	P30307	CDC25C	P45984	MAPK9	S191	E196K	196	Missense	distal	5	no	140.501	140.645	EPSD	TCGA;ICGC	140.458	Up-regulation
CMGC_MAPK_JNK_MAPK9_ST	P30307	CDC25C	P45984	MAPK9	S214	P215Q	215	Missense	proximal	1	no	155.121	135.009	EPSD	TCGA;ICGC;COSMIC	140.458	Loss
CMGC_MAPK_JNK_MAPK9_ST	P30307	CDC25C	P45984	MAPK9	S214	R213H	213	Missense	proximal	-1	no	155.121	154.853	EPSD	TCGA;ICGC;COSMIC	140.458	Down-regulation
CMGC_MAPK_JNK_MAPK9_ST	P30307	CDC25C	P45984	MAPK9	S214	R213C	213	Missense	proximal	-1	no	155.121	154.940	EPSD	TCGA;ICGC;COSMIC	140.458	Down-regulation
CMGC_MAPK_JNK_MAPK9_ST	P30307	CDC25C	P45984	MAPK9	S214	S214F	214	Missense	central	0	yes	155.121	0.000	EPSD	TCGA;ICGC;COSMIC	140.458	Loss
CMGC_MAPK_JNK_MAPK9_ST	P30307	CDC25C	P45984	MAPK9	S214	L221S	221	Missense	distal	7	no	155.121	154.711	EPSD	TCGA;ICGC;COSMIC	140.458	Down-regulation
CMGC_MAPK_JNK_MAPK9_ST	P30307	CDC25C	P45984	MAPK9	S214	P218S	218	Missense	distal	4	no	155.121	155.223	EPSD	TCGA;ICGC	140.458	Up-regulation
CMGC_MAPK_JNK_MAPK9_ST	P31645	SLC6A4	P45984	MAPK9	S52	D58N	58	Missense	distal	6	no	155.179	155.644	EPSD	TCGA;ICGC;COSMIC	140.458	Up-regulation
CMGC_MAPK_JNK_MAPK9_ST	P31645	SLC6A4	P45984	MAPK9	S52	A55T	55	Missense	distal	3	no	155.179	154.968	EPSD	TCGA;ICGC;COSMIC	140.458	Down-regulation
CMGC_MAPK_JNK_MAPK9_ST	P31645	SLC6A4	P45984	MAPK9	S52	A55V	55	Missense	distal	3	no	155.179	155.006	EPSD	TCGA;ICGC;COSMIC	140.458	Down-regulation
CMGC_MAPK_JNK_MAPK9_ST	P31645	SLC6A4	P45984	MAPK9	T67	L74R	74	Missense	distal	7	no	141.478	140.645	EPSD	TCGA;ICGC;COSMIC	140.458	Down-regulation
CMGC_MAPK_JNK_MAPK9_ST	P31645	SLC6A4	P45984	MAPK9	T67	S62F	62	Missense	distal	-5	no	141.478	141.621	EPSD	TCGA;ICGC;COSMIC	140.458	Up-regulation
CMGC_MAPK_JNK_MAPK9_ST	P31645	SLC6A4	P45984	MAPK9	S559	L557P	557	Missense	proximal	-2	no	150.586	151.660	EPSD	TCGA;ICGC;COSMIC	140.458	Up-regulation
CMGC_MAPK_JNK_MAPK9_ST	P31645	SLC6A4	P45984	MAPK9	T613	R607C	607	Missense	distal	-6	no	144.631	144.265	EPSD	TCGA;ICGC	140.458	Down-regulation
CMGC_MAPK_JNK_MAPK9_ST	Q8IW41	MAPKAPK5	P45984	MAPK9	T182	T182P	182	Missense	central	0	yes	153.789	0.000	PhosphoSitePlus	TCGA;ICGC;COSMIC	140.458	Loss
CMGC_MAPK_JNK_MAPK9_ST	Q8IW41	MAPKAPK5	P45984	MAPK9	T182	G178S	178	Missense	distal	-4	no	153.789	155.323	PhosphoSitePlus	TCGA;ICGC;COSMIC	140.458	Up-regulation
CMGC_MAPK_JNK_MAPK9_ST	Q8IW41	MAPKAPK5	P45984	MAPK9	T186	T182P	182	Missense	distal	-4	no	151.094	152.986	EPSD	TCGA;ICGC;COSMIC	140.458	Up-regulation
CMGC_MAPK_JNK_MAPK9_ST	Q8IW41	MAPKAPK5	P45984	MAPK9	S212	T214M	214	Missense	proximal	2	no	161.944	161.756	EPSD	TCGA;ICGC;COSMIC	140.458	Down-regulation
CMGC_MAPK_JNK_MAPK9_ST	Q8IW41	MAPKAPK5	P45984	MAPK9	T214	T214M	214	Missense	central	0	yes	156.012	0.000	EPSD	TCGA;ICGC;COSMIC	140.458	Loss
CMGC_MAPK_JNK_MAPK9_ST	P29966	MARCKS	P45984	MAPK9	S27	P28L	28	Missense	proximal	1	no	160.346	115.444	EPSD	TCGA;ICGC;COSMIC	140.458	Loss
CMGC_MAPK_JNK_MAPK9_ST	P29966	MARCKS	P45984	MAPK9	S27	S29F	29	Missense	proximal	2	no	160.346	160.583	EPSD	TCGA;ICGC;COSMIC	140.458	Up-regulation
CMGC_MAPK_JNK_MAPK9_ST	P29966	MARCKS	P45984	MAPK9	S308	A305T	305	Missense	distal	-3	no	145.391	144.143	EPSD	TCGA;ICGC;COSMIC	140.458	Down-regulation
CMGC_MAPK_JNK_MAPK9_ST	P29966	MARCKS	P45984	MAPK9	S308	A306S	306	Missense	proximal	-2	no	145.391	142.900	EPSD	TCGA;ICGC;COSMIC	140.458	Down-regulation
CMGC_MAPK_JNK_MAPK9_ST	P29966	MARCKS	P45984	MAPK9	S308	S308L	308	Missense	central	0	yes	145.391	0.000	EPSD	TCGA;ICGC;COSMIC	140.458	Loss
CMGC_MAPK_JNK_MAPK9_ST	P29966	MARCKS	P45984	MAPK9	S314	S308L	308	Missense	distal	-6	no	145.133	144.783	EPSD	TCGA;ICGC;COSMIC	140.458	Down-regulation
CMGC_MAPK_JNK_MAPK9_ST	P29966	MARCKS	P45984	MAPK9	S314	E320K	320	Missense	distal	6	no	145.133	144.980	EPSD	TCGA;ICGC;COSMIC	140.458	Down-regulation
CMGC_MAPK_JNK_MAPK9_ST	Q15750	TAB1	P45984	MAPK9	T18	D20Y	20	Missense	proximal	2	no	144.934	145.116	EPSD	TCGA	140.458	Up-regulation
CMGC_MAPK_JNK_MAPK9_ST	Q15750	TAB1	P45984	MAPK9	T18	W17C	17	Missense	proximal	-1	no	144.934	145.230	EPSD	TCGA;ICGC;COSMIC	140.458	Up-regulation
CMGC_MAPK_JNK_MAPK9_ST	Q15750	TAB1	P45984	MAPK9	S339	R336C	336	Missense	distal	-3	no	144.136	142.578	EPSD	TCGA;ICGC;COSMIC	140.458	Down-regulation
CMGC_MAPK_JNK_MAPK9_ST	Q15750	TAB1	P45984	MAPK9	S339	R336H	336	Missense	distal	-3	no	144.136	141.750	EPSD	TCGA;ICGC;COSMIC	140.458	Down-regulation
CMGC_MAPK_JNK_MAPK9_ST	Q15750	TAB1	P45984	MAPK9	S339	R333P	333	Missense	distal	-6	no	144.136	144.024	EPSD	TCGA;ICGC;COSMIC	140.458	Down-regulation
CMGC_MAPK_JNK_MAPK9_ST	Q15750	TAB1	P45984	MAPK9	S339	D340N	340	Missense	proximal	1	no	144.136	-40.827	EPSD	TCGA;ICGC;COSMIC	140.458	Loss
CMGC_MAPK_JNK_MAPK9_ST	Q15750	TAB1	P45984	MAPK9	S423	A430T	430	Missense	distal	7	no	140.298	140.896	EPSD	TCGA;ICGC;COSMIC	140.458	Gain
CMGC_MAPK_JNK_MAPK9_ST	Q15750	TAB1	P45984	MAPK9	S423	G420R	420	Missense	distal	-3	no	140.298	142.281	EPSD	TCGA;ICGC	140.458	Gain
CMGC_MAPK_JNK_MAPK9_ST	Q15750	TAB1	P45984	MAPK9	T431	E429K	429	Missense	proximal	-2	no	154.477	152.409	EPSD	TCGA;ICGC;COSMIC	140.458	Down-regulation
CMGC_MAPK_JNK_MAPK9_ST	Q15750	TAB1	P45984	MAPK9	T431	A430T	430	Missense	proximal	-1	no	154.477	154.217	EPSD	TCGA;ICGC;COSMIC	140.458	Down-regulation
CMGC_MAPK_JNK_MAPK9_ST	Q15750	TAB1	P45984	MAPK9	T431	T433I	433	Missense	proximal	2	no	154.477	154.448	EPSD	TCGA;ICGC;COSMIC	140.458	Down-regulation
CMGC_MAPK_JNK_MAPK9_ST	Q15750	TAB1	P45984	MAPK9	S438	T433I	433	Missense	distal	-5	no	155.886	155.934	PhosphoSitePlus	TCGA;ICGC;COSMIC	140.458	Up-regulation
CMGC_MAPK_JNK_MAPK9_ST	Q9UQF2	MAPK8IP1	P45984	MAPK9	S235	R238H	238	Missense	distal	3	no	153.307	153.036	EPSD	TCGA;COSMIC	140.458	Down-regulation
CMGC_MAPK_JNK_MAPK9_ST	Q9UQF2	MAPK8IP1	P45984	MAPK9	T284	E279K	279	Missense	distal	-5	no	151.662	151.695	EPSD	TCGA;COSMIC	140.458	Up-regulation
CMGC_MAPK_JNK_MAPK9_ST	Q9UQF2	MAPK8IP1	P45984	MAPK9	S311	S311F	311	Missense	central	0	yes	141.853	0.000	EPSD	TCGA;COSMIC	140.458	Loss
CMGC_MAPK_JNK_MAPK9_ST	Q9UQF2	MAPK8IP1	P45984	MAPK9	S311	R306L	306	Missense	distal	-5	no	141.853	141.960	EPSD	TCGA;COSMIC	140.458	Up-regulation
CMGC_MAPK_JNK_MAPK9_ST	Q9UQF2	MAPK8IP1	P45984	MAPK9	S311	R306Q	306	Missense	distal	-5	no	141.853	141.837	EPSD	TCGA;COSMIC	140.458	Down-regulation
CMGC_MAPK_JNK_MAPK9_ST	Q9UQF2	MAPK8IP1	P45984	MAPK9	S311	S305N	305	Missense	distal	-6	no	141.853	141.958	EPSD	TCGA;COSMIC	140.458	Up-regulation
CMGC_MAPK_JNK_MAPK9_ST	Q9UQF2	MAPK8IP1	P45984	MAPK9	S311	D312N	312	Missense	proximal	1	no	141.853	-43.110	EPSD	TCGA;COSMIC	140.458	Loss
CMGC_MAPK_JNK_MAPK9_ST	Q9UQF2	MAPK8IP1	P45984	MAPK9	S341	E343D	343	Missense	proximal	2	no	160.263	160.388	EPSD	TCGA	140.458	Up-regulation
CMGC_MAPK_JNK_MAPK9_ST	Q9UQF2	MAPK8IP1	P45984	MAPK9	S369	L374P	374	Missense	distal	5	no	143.394	142.625	EPSD	TCGA;COSMIC	140.458	Down-regulation
CMGC_MAPK_JNK_MAPK9_ST	Q9UQF2	MAPK8IP1	P45984	MAPK9	S369	S375P	375	Missense	distal	6	no	143.394	143.367	EPSD	TCGA	140.458	Down-regulation
CMGC_MAPK_JNK_MAPK9_ST	Q9UQF2	MAPK8IP1	P45984	MAPK9	S421	A426V	426	Missense	distal	5	no	145.512	145.929	EPSD	TCGA;COSMIC	140.458	Up-regulation
CMGC_MAPK_JNK_MAPK9_ST	Q9UQF2	MAPK8IP1	P45984	MAPK9	S421	V419I	419	Missense	proximal	-2	no	145.512	146.650	EPSD	TCGA;COSMIC	140.458	Up-regulation
CMGC_MAPK_JNK_MAPK9_ST	Q9UQF2	MAPK8IP1	P45984	MAPK9	S421	S425L	425	Missense	distal	4	no	145.512	145.786	EPSD	TCGA;COSMIC	140.458	Up-regulation
CMGC_MAPK_JNK_MAPK9_ST	Q9UQF2	MAPK8IP1	P45984	MAPK9	S447	S444F	444	Missense	distal	-3	no	143.353	140.068	EPSD	TCGA;COSMIC	140.458	Loss
CMGC_MAPK_JNK_MAPK9_ST	Q9UQF2	MAPK8IP1	P45984	MAPK9	T448	S444F	444	Missense	distal	-4	no	164.131	160.849	EPSD	TCGA;COSMIC	140.458	Down-regulation
CMGC_MAPK_JNK_MAPK9_ST	P98177	FOXO4	P45984	MAPK9	S111	A113V	113	Missense	proximal	2	no	141.839	141.980	EPSD	TCGA;COSMIC	140.458	Up-regulation
CMGC_MAPK_JNK_MAPK9_ST	P98177	FOXO4	P45984	MAPK9	S111	Q112H	112	Missense	proximal	1	no	141.839	1.846	EPSD	TCGA;COSMIC	140.458	Loss
CMGC_MAPK_JNK_MAPK9_ST	P98177	FOXO4	P45984	MAPK9	T227	E224K	224	Missense	distal	-3	no	158.510	157.235	EPSD	TCGA;COSMIC	140.458	Down-regulation
CMGC_MAPK_JNK_MAPK9_ST	P98177	FOXO4	P45984	MAPK9	T227	G233D	233	Missense	distal	6	no	158.510	158.523	EPSD	TCGA;COSMIC	140.458	Up-regulation
CMGC_MAPK_JNK_MAPK9_ST	P98177	FOXO4	P45984	MAPK9	T227	P231T	231	Missense	distal	4	no	158.510	158.709	EPSD	TCGA;COSMIC	140.458	Up-regulation
CMGC_MAPK_JNK_MAPK9_ST	P98177	FOXO4	P45984	MAPK9	S230	E224K	224	Missense	distal	-6	no	161.553	161.412	EPSD	TCGA;COSMIC	140.458	Down-regulation
CMGC_MAPK_JNK_MAPK9_ST	P98177	FOXO4	P45984	MAPK9	S230	G233D	233	Missense	distal	3	no	161.553	161.602	EPSD	TCGA;COSMIC	140.458	Up-regulation
CMGC_MAPK_JNK_MAPK9_ST	P98177	FOXO4	P45984	MAPK9	S230	P231T	231	Missense	proximal	1	no	161.553	142.358	EPSD	TCGA;COSMIC	140.458	Down-regulation
CMGC_MAPK_JNK_MAPK9_ST	P98177	FOXO4	P45984	MAPK9	S241	R247H	247	Missense	distal	6	no	154.833	154.542	EPSD	TCGA;COSMIC;CCLE	140.458	Down-regulation
CMGC_MAPK_JNK_MAPK9_ST	P98177	FOXO4	P45984	MAPK9	S241	N246D	246	Missense	distal	5	no	154.833	155.627	EPSD	TCGA;COSMIC	140.458	Up-regulation
CMGC_MAPK_JNK_MAPK9_ST	P98177	FOXO4	P45984	MAPK9	S241	R247C	247	Missense	distal	6	no	154.833	154.659	EPSD	TCGA;COSMIC	140.458	Down-regulation
CMGC_MAPK_JNK_MAPK9_ST	P98177	FOXO4	P45984	MAPK9	T451	A448D	448	Missense	distal	-3	no	160.311	159.300	EPSD;PhosphoSitePlus	TCGA;COSMIC	140.458	Down-regulation
CMGC_MAPK_JNK_MAPK9_ST	P98177	FOXO4	P45984	MAPK9	T451	P446L	446	Missense	distal	-5	no	160.311	160.411	EPSD;PhosphoSitePlus	TCGA;COSMIC	140.458	Up-regulation
CMGC_MAPK_JNK_MAPK9_ST	P98177	FOXO4	P45984	MAPK9	T455	A448D	448	Missense	distal	-7	no	161.686	160.033	PhosphoSitePlus;EPSD	TCGA;COSMIC	140.458	Down-regulation
CMGC_MAPK_JNK_MAPK9_ST	Q9NYV6	RRN3	P45984	MAPK9	S44	R51W	51	Missense	distal	7	no	152.328	153.442	EPSD	TCGA;ICGC;COSMIC	140.458	Up-regulation
CMGC_MAPK_JNK_MAPK9_ST	Q9NYV6	RRN3	P45984	MAPK9	S44	R47S	47	Missense	distal	3	no	152.328	152.171	EPSD	TCGA;ICGC;COSMIC	140.458	Down-regulation
CMGC_MAPK_JNK_MAPK9_ST	Q9NYV6	RRN3	P45984	MAPK9	S170	E164K	164	Missense	distal	-6	no	144.726	144.585	EPSD	TCGA;ICGC;COSMIC	140.458	Down-regulation
CMGC_MAPK_JNK_MAPK9_ST	Q9NYV6	RRN3	P45984	MAPK9	S170	E175K	175	Missense	distal	5	no	144.726	144.870	EPSD	TCGA;ICGC;COSMIC	140.458	Up-regulation
CMGC_MAPK_JNK_MAPK9_ST	Q9NYV6	RRN3	P45984	MAPK9	S170	D174E	174	Missense	distal	4	no	144.726	144.360	EPSD	TCGA;ICGC;COSMIC	140.458	Down-regulation
CMGC_MAPK_JNK_MAPK9_ST	Q9NYV6	RRN3	P45984	MAPK9	T200	R195I	195	Missense	distal	-5	no	157.330	157.413	PhosphoSitePlus	TCGA;ICGC;COSMIC	140.458	Up-regulation
CMGC_MAPK_JNK_MAPK9_ST	Q9NYV6	RRN3	P45984	MAPK9	T623	V619M	619	Missense	distal	-4	no	155.505	156.483	EPSD	TCGA;COSMIC	140.458	Up-regulation
CMGC_MAPK_JNK_MAPK9_ST	Q9NYV6	RRN3	P45984	MAPK9	S633	S640F	640	Missense	distal	7	no	147.592	148.388	EPSD	TCGA;COSMIC	140.458	Up-regulation
CMGC_MAPK_JNK_MAPK9_ST	Q9NYV6	RRN3	P45984	MAPK9	S633	F631L	631	Missense	proximal	-2	no	147.592	152.549	EPSD	TCGA;COSMIC	140.458	Up-regulation
CMGC_MAPK_JNK_MAPK9_ST	Q9NYV6	RRN3	P45984	MAPK9	S640	S640F	640	Missense	central	0	yes	144.709	0.000	EPSD	TCGA;COSMIC	140.458	Loss
CMGC_MAPK_JNK_MAPK9_ST	Q9NYV6	RRN3	P45984	MAPK9	S640	P641S	641	Missense	proximal	1	no	144.709	-136.085	EPSD	TCGA;COSMIC	140.458	Loss
CMGC_MAPK_JNK_MAPK9_ST	Q9NYV6	RRN3	P45984	MAPK9	S649	S649I	649	Missense	central	0	yes	149.789	0.000	EPSD	TCGA;COSMIC	140.458	Loss
CMGC_MAPK_JNK_MAPK9_ST	Q9BQQ3	GORASP1	P45984	MAPK9	T216	G215D	215	Missense	proximal	-1	no	149.327	149.248	EPSD	TCGA;COSMIC	140.458	Down-regulation
CMGC_MAPK_JNK_MAPK9_ST	Q9BQQ3	GORASP1	P45984	MAPK9	T216	P218L	218	Missense	proximal	2	no	149.327	149.482	EPSD	TCGA;COSMIC	140.458	Up-regulation
CMGC_MAPK_JNK_MAPK9_ST	Q06481	APLP2	P45984	MAPK9	T736	H741R	741	Missense	distal	5	no	161.299	160.549	PhosphoSitePlus	TCGA;COSMIC	140.458	Down-regulation
AGC_NDR_LATS_LATS2_ST	Q9NQS7	INCENP	Q9NRM7	LATS2	S50	R43H	43	Missense	distal	-7	no	0.053	0.052	EPSD	TCGA;ICGC;COSMIC;GDSC;CCLE	0.004	Down-regulation
AGC_NDR_LATS_LATS2_ST	Q9NQS7	INCENP	Q9NRM7	LATS2	S72	R69K	69	Missense	distal	-3	no	0.048	-0.001	EPSD	TCGA	0.004	Loss
AGC_NDR_LATS_LATS2_ST	Q9NQS7	INCENP	Q9NRM7	LATS2	S91	R88H	88	Missense	distal	-3	no	0.052	0.003	EPSD	TCGA;ICGC	0.004	Loss
AGC_NDR_LATS_LATS2_ST	Q9NQS7	INCENP	Q9NRM7	LATS2	S93	R88H	88	Missense	distal	-5	no	0.000	0.013	EPSD	TCGA;ICGC	0.004	Gain
AGC_NDR_LATS_LATS2_ST	Q9NQS7	INCENP	Q9NRM7	LATS2	S103	R100S	100	Missense	distal	-3	no	0.056	0.003	EPSD	TCGA;ICGC;COSMIC	0.004	Loss
AGC_NDR_LATS_LATS2_ST	Q9NQS7	INCENP	Q9NRM7	LATS2	S103	S103I	103	Missense	central	0	yes	0.056	0.000	EPSD	TCGA;ICGC;COSMIC	0.004	Loss
AGC_NDR_LATS_LATS2_ST	Q9NQS7	INCENP	Q9NRM7	LATS2	S197	R194H	194	Missense	distal	-3	no	0.051	0.001	EPSD	TCGA;ICGC;COSMIC	0.004	Loss
AGC_NDR_LATS_LATS2_ST	Q9NQS7	INCENP	Q9NRM7	LATS2	T199	R194H	194	Missense	distal	-5	no	-0.006	0.006	EPSD	TCGA;ICGC;COSMIC	0.004	Gain
AGC_NDR_LATS_LATS2_ST	Q9NQS7	INCENP	Q9NRM7	LATS2	S255	S255P	255	Missense	central	0	yes	0.050	0.000	EPSD	TCGA;ICGC;COSMIC	0.004	Loss
AGC_NDR_LATS_LATS2_ST	Q9NQS7	INCENP	Q9NRM7	LATS2	S300	Q301E	301	Missense	proximal	1	no	0.049	0.050	EPSD	TCGA;ICGC;COSMIC	0.004	Up-regulation
AGC_NDR_LATS_LATS2_ST	Q9NQS7	INCENP	Q9NRM7	LATS2	S300	R297C	297	Missense	distal	-3	no	0.049	0.002	EPSD	TCGA;ICGC;COSMIC	0.004	Loss
AGC_NDR_LATS_LATS2_ST	Q9NQS7	INCENP	Q9NRM7	LATS2	T478	T478I	478	Missense	central	0	yes	0.046	0.000	EPSD	TCGA;ICGC;COSMIC	0.004	Loss
AGC_NDR_LATS_LATS2_ST	Q9NQS7	INCENP	Q9NRM7	LATS2	S894	S894F	894	Missense	central	0	yes	0.062	0.000	PhosphoSitePlus	TCGA;ICGC;COSMIC	0.004	Loss
AGC_NDR_LATS_LATS2_ST	Q9NQS7	INCENP	Q9NRM7	LATS2	S899	G904D	904	Missense	distal	5	no	0.004	0.005	EPSD	TCGA;ICGC	0.004	Up-regulation
AGC_NDR_LATS_LATS2_ST	P38936	CDKN1A	Q9NRM7	LATS2	T57	E56K	56	Missense	proximal	-1	no	0.003	0.004	EPSD	TCGA;ICGC;COSMIC	0.004	Gain
AGC_NDR_LATS_LATS2_ST	P38936	CDKN1A	Q9NRM7	LATS2	T97	R94W	94	Missense	distal	-3	no	0.047	0.000	EPSD	TCGA;ICGC;COSMIC	0.004	Loss
AGC_NDR_LATS_LATS2_ST	P38936	CDKN1A	Q9NRM7	LATS2	T97	R93S	93	Missense	distal	-4	no	0.047	0.046	EPSD	TCGA;ICGC;COSMIC	0.004	Down-regulation
AGC_NDR_LATS_LATS2_ST	P38936	CDKN1A	Q9NRM7	LATS2	T97	R94P	94	Missense	distal	-3	no	0.047	-0.006	EPSD	TCGA;ICGC;COSMIC	0.004	Loss
AGC_NDR_LATS_LATS2_ST	P38936	CDKN1A	Q9NRM7	LATS2	T145	R142W	142	Missense	distal	-3	no	0.041	-0.006	EPSD	TCGA;ICGC;COSMIC;GDSC;CCLE	0.004	Loss
AGC_NDR_LATS_LATS2_ST	P38936	CDKN1A	Q9NRM7	LATS2	S146	R142W	142	Missense	distal	-4	no	0.054	0.053	PhosphoSitePlus	TCGA;ICGC;COSMIC;GDSC;CCLE	0.004	Down-regulation
AGC_NDR_LATS_LATS2_ST	P38936	CDKN1A	Q9NRM7	LATS2	S153	R155H	155	Missense	proximal	2	no	0.002	0.004	EPSD	TCGA;ICGC;COSMIC;CCLE	0.004	Gain
AGC_NDR_LATS_LATS2_ST	P38936	CDKN1A	Q9NRM7	LATS2	S160	R155H	155	Missense	distal	-5	no	-0.005	0.007	EPSD	TCGA;ICGC;COSMIC;CCLE	0.004	Gain
AGC_NDR_LATS_LATS2_ST	P00519	ABL1	Q9NRM7	LATS2	S620	S620G	620	Missense	central	0	yes	0.046	0.000	EPSD	TCGA;COSMIC	0.004	Loss
AGC_NDR_LATS_LATS2_ST	P00519	ABL1	Q9NRM7	LATS2	S620	S620R	620	Missense	central	0	yes	0.046	0.000	EPSD	TCGA;COSMIC	0.004	Loss
AGC_NDR_LATS_LATS2_ST	P46937	YAP1	Q9NRM7	LATS2	S61	S61W	61	Missense	central	0	yes	0.063	0.000	PhosphoSitePlus;EPSD	TCGA;ICGC;COSMIC	0.004	Loss
AGC_NDR_LATS_LATS2_ST	P46937	YAP1	Q9NRM7	LATS2	S109	R106Q	106	Missense	distal	-3	no	0.061	0.012	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC;CCLE	0.004	Down-regulation
AGC_NDR_LATS_LATS2_ST	P46937	YAP1	Q9NRM7	LATS2	S109	S109N	109	Missense	central	0	yes	0.061	0.000	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	0.004	Loss
AGC_NDR_LATS_LATS2_ST	P46937	YAP1	Q9NRM7	LATS2	S127	R124P	124	Missense	distal	-3	no	0.064	0.011	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	0.004	Down-regulation
AGC_NDR_LATS_LATS2_ST	P46937	YAP1	Q9NRM7	LATS2	S127	R124Q	124	Missense	distal	-3	no	0.064	0.015	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	0.004	Down-regulation
AGC_NDR_LATS_LATS2_ST	P46937	YAP1	Q9NRM7	LATS2	S131	G135E	135	Missense	distal	4	no	0.011	0.010	EPSD	TCGA;ICGC;COSMIC	0.004	Down-regulation
AGC_NDR_LATS_LATS2_ST	P46937	YAP1	Q9NRM7	LATS2	S163	Q158H	158	Missense	distal	-5	no	-0.002	0.009	EPSD	TCGA;ICGC;COSMIC	0.004	Gain
AGC_NDR_LATS_LATS2_ST	Q9Y2J4	AMOTL2	Q9NRM7	LATS2	T597	S602Y	602	Missense	distal	5	no	0.049	0.048	EPSD	TCGA;COSMIC	0.004	Down-regulation
AGC_NDR_LATS_LATS2_ST	Q9Y2J4	AMOTL2	Q9NRM7	LATS2	S661	R663W	663	Missense	proximal	2	no	0.004	0.005	EPSD	TCGA;ICGC;COSMIC	0.004	Up-regulation
AGC_NDR_LATS_LATS2_ST	P61981	YWHAG	Q9NRM7	LATS2	S59	V52I	52	Missense	distal	-7	no	0.052	0.053	PhosphoSitePlus	TCGA;ICGC;COSMIC	0.004	Up-regulation
AGC_NDR_LATS_LATS2_ST	P61981	YWHAG	Q9NRM7	LATS2	S71	S71Y	71	Missense	central	0	yes	0.006	0.000	EPSD	TCGA;ICGC;COSMIC	0.004	Loss
AGC_NDR_LATS_LATS2_ST	Q02241	KIF23	Q9NRM7	LATS2	T8	R10W	10	Missense	proximal	2	no	0.047	0.048	EPSD	TCGA;ICGC;COSMIC	0.004	Up-regulation
AGC_NDR_LATS_LATS2_ST	Q02241	KIF23	Q9NRM7	LATS2	T13	G17R	17	Missense	distal	4	no	0.047	0.046	EPSD	TCGA;ICGC;COSMIC	0.004	Down-regulation
AGC_NDR_LATS_LATS2_ST	Q02241	KIF23	Q9NRM7	LATS2	T13	R10W	10	Missense	distal	-3	no	0.047	0.000	EPSD	TCGA;ICGC;COSMIC	0.004	Loss
AGC_NDR_LATS_LATS2_ST	Q02241	KIF23	Q9NRM7	LATS2	T20	G17R	17	Missense	distal	-3	no	0.002	0.054	EPSD	TCGA;ICGC;COSMIC	0.004	Gain
AGC_NDR_LATS_LATS2_ST	Q02241	KIF23	Q9NRM7	LATS2	T56	Q53R	53	Missense	distal	-3	no	0.001	0.050	EPSD	TCGA;ICGC;COSMIC	0.004	Gain
AGC_NDR_LATS_LATS2_ST	Q02241	KIF23	Q9NRM7	LATS2	T121	K118Q	118	Missense	distal	-3	no	0.003	0.004	EPSD	TCGA;ICGC	0.004	Gain
AGC_NDR_LATS_LATS2_ST	Q02241	KIF23	Q9NRM7	LATS2	S125	M122V	122	Missense	distal	-3	no	0.012	0.011	EPSD	TCGA;ICGC;COSMIC	0.004	Down-regulation
AGC_NDR_LATS_LATS2_ST	Q02241	KIF23	Q9NRM7	LATS2	T292	R288H	288	Missense	distal	-4	no	0.006	0.005	EPSD	TCGA;COSMIC	0.004	Down-regulation
AGC_NDR_LATS_LATS2_ST	Q02241	KIF23	Q9NRM7	LATS2	T292	R288C	288	Missense	distal	-4	no	0.006	0.005	EPSD	TCGA;COSMIC	0.004	Down-regulation
AGC_NDR_LATS_LATS2_ST	Q02241	KIF23	Q9NRM7	LATS2	S298	S298F	298	Missense	central	0	yes	0.010	0.000	EPSD	TCGA;COSMIC	0.004	Loss
AGC_NDR_LATS_LATS2_ST	Q02241	KIF23	Q9NRM7	LATS2	S303	K308T	308	Missense	distal	5	no	0.054	0.053	EPSD	TCGA	0.004	Down-regulation
AGC_NDR_LATS_LATS2_ST	Q02241	KIF23	Q9NRM7	LATS2	S552	Q554H	554	Missense	proximal	2	no	0.003	0.004	EPSD	TCGA;COSMIC	0.004	Gain
AGC_NDR_LATS_LATS2_ST	Q02241	KIF23	Q9NRM7	LATS2	S716	R713H	713	Missense	distal	-3	no	0.065	0.016	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	0.004	Down-regulation
AGC_NDR_LATS_LATS2_ST	Q02241	KIF23	Q9NRM7	LATS2	S718	R713H	713	Missense	distal	-5	no	-0.001	0.011	EPSD	TCGA;ICGC;COSMIC	0.004	Gain
AGC_NDR_LATS_LATS2_ST	Q02241	KIF23	Q9NRM7	LATS2	S814	S814F	814	Missense	central	0	yes	0.066	0.000	PhosphoSitePlus;EPSD	TCGA;COSMIC	0.004	Loss
AGC_NDR_LATS_LATS2_ST	Q02241	KIF23	Q9NRM7	LATS2	S943	E938K	938	Missense	distal	-5	no	0.049	0.051	EPSD	TCGA;COSMIC	0.004	Up-regulation
AGC_NDR_LATS_LATS2_ST	Q02241	KIF23	Q9NRM7	LATS2	S943	R940T	940	Missense	distal	-3	no	0.049	-0.002	EPSD	TCGA;COSMIC	0.004	Loss
AGC_NDR_LATS_LATS2_ST	Q4VCS5	AMOT	Q9NRM7	LATS2	S175	R172H	172	Missense	distal	-3	no	0.060	0.010	PhosphoSitePlus	TCGA;ICGC	0.004	Down-regulation
AGC_NDR_LATS_LATS2_ST	Q4VCS5	AMOT	Q9NRM7	LATS2	S196	P192S	192	Missense	distal	-4	no	0.007	0.008	EPSD	TCGA;ICGC;COSMIC	0.004	Up-regulation
AGC_NDR_LATS_LATS2_ST	Q4VCS5	AMOT	Q9NRM7	LATS2	S313	G317V	317	Missense	distal	4	no	0.007	0.006	EPSD	TCGA	0.004	Down-regulation
AGC_NDR_LATS_LATS2_ST	Q4VCS5	AMOT	Q9NRM7	LATS2	T709	S714F	714	Missense	distal	5	no	0.047	0.046	EPSD	TCGA;COSMIC	0.004	Down-regulation
AGC_NDR_LATS_LATS2_ST	Q4VCS5	AMOT	Q9NRM7	LATS2	T750	R747M	747	Missense	distal	-3	no	0.047	-0.002	EPSD	TCGA;ICGC;COSMIC	0.004	Loss
AGC_NDR_LATS_LATS2_ST	Q4VCS5	AMOT	Q9NRM7	LATS2	T750	E745D	745	Missense	distal	-5	no	0.047	0.048	EPSD	TCGA;COSMIC	0.004	Up-regulation
AGC_NDR_LATS_LATS2_ST	Q4VCS5	AMOT	Q9NRM7	LATS2	S803	S800F	800	Missense	distal	-3	no	0.000	0.005	EPSD	TCGA;COSMIC	0.004	Gain
AGC_NDR_LATS_LATS2_ST	Q4VCS5	AMOT	Q9NRM7	LATS2	T806	S803F	803	Missense	distal	-3	no	0.010	0.015	EPSD	TCGA;CCLE	0.004	Up-regulation
AGC_NDR_LATS_LATS2_ST	Q4VCS5	AMOT	Q9NRM7	LATS2	T806	H801Y	801	Missense	distal	-5	no	0.010	0.000	EPSD	TCGA;COSMIC	0.004	Loss
AGC_NDR_LATS_LATS2_ST	Q4VCS5	AMOT	Q9NRM7	LATS2	T806	H801L	801	Missense	distal	-5	no	0.010	0.000	EPSD	TCGA;ICGC;COSMIC	0.004	Loss
AGC_NDR_LATS_LATS2_ST	Q4VCS5	AMOT	Q9NRM7	LATS2	S808	L805R	805	Missense	distal	-3	no	-0.003	0.047	EPSD	TCGA;COSMIC	0.004	Gain
AGC_NDR_LATS_LATS2_ST	Q4VCS5	AMOT	Q9NRM7	LATS2	S839	A834G	834	Missense	distal	-5	no	0.006	0.007	EPSD	TCGA;COSMIC	0.004	Up-regulation
AGC_NDR_LATS_LATS2_ST	Q4VCS5	AMOT	Q9NRM7	LATS2	S839	S839F	839	Missense	central	0	yes	0.006	0.000	EPSD	TCGA;COSMIC	0.004	Loss
AGC_NDR_LATS_LATS2_ST	Q4VCS5	AMOT	Q9NRM7	LATS2	S859	K856R	856	Missense	distal	-3	no	0.013	0.062	EPSD	TCGA;COSMIC	0.004	Up-regulation
AGC_NDR_LATS_LATS2_ST	Q4VCS5	AMOT	Q9NRM7	LATS2	S863	K856R	856	Missense	distal	-7	no	0.046	0.047	EPSD	TCGA;COSMIC	0.004	Up-regulation
AGC_NDR_LATS_LATS2_ST	Q9GZV5	WWTR1	Q9NRM7	LATS2	S89	H84D	84	Missense	distal	-5	no	0.071	0.061	PhosphoSitePlus	TCGA;ICGC;COSMIC	0.004	Down-regulation
AGC_NDR_LATS_LATS2_ST	Q9GZV5	WWTR1	Q9NRM7	LATS2	S89	S89W	89	Missense	central	0	yes	0.071	0.000	PhosphoSitePlus	TCGA;ICGC;COSMIC	0.004	Loss
AGC_NDR_LATS_LATS2_ST	Q9GZV5	WWTR1	Q9NRM7	LATS2	S117	D122N	122	Missense	distal	5	no	0.059	0.060	EPSD	TCGA;ICGC;COSMIC	0.004	Up-regulation
AGC_NDR_LATS_LATS2_ST	Q9GZV5	WWTR1	Q9NRM7	LATS2	S174	Q179H	179	Missense	distal	5	no	0.009	0.008	EPSD	TCGA;ICGC;COSMIC	0.004	Down-regulation
AGC_NDR_LATS_LATS2_ST	Q9GZV5	WWTR1	Q9NRM7	LATS2	S311	H306Y	306	Missense	distal	-5	no	0.062	0.052	EPSD	TCGA;ICGC;COSMIC	0.004	Down-regulation
AGC_NDR_LATS_LATS2_ST	O95863	SNAI1	Q9NRM7	LATS2	T177	V181I	181	Missense	distal	4	no	0.059	0.060	EPSD	TCGA;ICGC;COSMIC	0.004	Up-regulation
AGC_NDR_LATS_LATS2_ST	O95863	SNAI1	Q9NRM7	LATS2	T177	R174Q	174	Missense	distal	-3	no	0.059	0.010	EPSD	TCGA;ICGC	0.004	Down-regulation
AGC_NDR_LATS_LATS2_ST	O95863	SNAI1	Q9NRM7	LATS2	T203	R200Q	200	Missense	distal	-3	no	0.064	0.015	PhosphoSitePlus	TCGA;ICGC;COSMIC	0.004	Down-regulation
AGC_NDR_LATS_LATS2_ST	O95863	SNAI1	Q9NRM7	LATS2	S231	V233G	233	Missense	proximal	2	no	0.010	0.011	EPSD	TCGA;ICGC	0.004	Up-regulation
AGC_NDR_LATS_LATS2_ST	O95863	SNAI1	Q9NRM7	LATS2	S246	R243Q	243	Missense	distal	-3	no	0.049	0.000	EPSD	TCGA;ICGC;COSMIC	0.004	Loss
AGC_NDR_LATS_LATS2_ST	O95863	SNAI1	Q9NRM7	LATS2	S246	R247P	247	Missense	proximal	1	no	0.049	0.048	EPSD	TCGA;ICGC;COSMIC	0.004	Down-regulation
AGC_NDR_LATS_LATS2_ST	O95863	SNAI1	Q9NRM7	LATS2	S246	C241F	241	Missense	distal	-5	no	0.049	0.048	EPSD	TCGA;ICGC;COSMIC	0.004	Down-regulation
Other_CAMKK_CAMKK-Meta_CAMKK2_ST	Q96EB6	SIRT1	Q96RR4	CAMKK2	S169	E164K	164	Missense	distal	-5	no	16.224	15.513	EPSD	TCGA;ICGC;COSMIC	15.642	Loss
Other_CAMKK_CAMKK-Meta_CAMKK2_ST	Q96EB6	SIRT1	Q96RR4	CAMKK2	T544	S549F	549	Missense	distal	5	no	24.552	18.762	EPSD	TCGA;COSMIC	15.642	Down-regulation
Other_CAMKK_CAMKK-Meta_CAMKK2_ST	Q96EB6	SIRT1	Q96RR4	CAMKK2	T544	R543I	543	Missense	proximal	-1	no	24.552	24.470	EPSD	TCGA;COSMIC	15.642	Down-regulation
Other_CAMKK_CAMKK-Meta_CAMKK2_ST	Q96EB6	SIRT1	Q96RR4	CAMKK2	S545	S549F	549	Missense	distal	4	no	22.282	19.689	EPSD	TCGA;COSMIC	15.642	Down-regulation
Other_CAMKK_CAMKK-Meta_CAMKK2_ST	Q96EB6	SIRT1	Q96RR4	CAMKK2	S545	R543I	543	Missense	proximal	-2	no	22.282	22.531	EPSD	TCGA;COSMIC	15.642	Up-regulation
Other_CAMKK_CAMKK-Meta_CAMKK2_ST	Q96EB6	SIRT1	Q96RR4	CAMKK2	S659	A655T	655	Missense	distal	-4	no	24.628	24.636	EPSD	TCGA;COSMIC	15.642	Up-regulation
Other_CAMKK_CAMKK-Meta_CAMKK2_ST	Q96EB6	SIRT1	Q96RR4	CAMKK2	S659	V665I	665	Missense	distal	6	no	24.628	24.655	EPSD	TCGA;COSMIC	15.642	Up-regulation
Other_CAMKK_CAMKK-Meta_CAMKK2_ST	Q96RR4	CAMKK2	Q96RR4	CAMKK2	T85	P82R	82	Missense	distal	-3	no	34.513	34.580	PhosphoSitePlus	TCGA;ICGC;COSMIC	15.642	Up-regulation
Other_CAMKK_CAMKK-Meta_CAMKK2_ST	Q96RR4	CAMKK2	Q96RR4	CAMKK2	T85	P82S	82	Missense	distal	-3	no	34.513	34.555	PhosphoSitePlus	TCGA;ICGC;COSMIC	15.642	Up-regulation
Other_CAMKK_CAMKK-Meta_CAMKK2_ST	Q96RR4	CAMKK2	Q96RR4	CAMKK2	T85	T85I	85	Missense	central	0	yes	34.513	0.000	PhosphoSitePlus	TCGA;ICGC;COSMIC	15.642	Loss
Other_CAMKK_CAMKK-Meta_CAMKK2_ST	Q96RR4	CAMKK2	Q96RR4	CAMKK2	S129	P124Q	124	Missense	distal	-5	no	18.509	19.803	EPSD	TCGA;ICGC;COSMIC	15.642	Up-regulation
Other_CAMKK_CAMKK-Meta_CAMKK2_ST	Q96RR4	CAMKK2	Q96RR4	CAMKK2	S132	R139G	139	Missense	distal	7	no	20.166	20.170	EPSD	TCGA;ICGC;COSMIC	15.642	Up-regulation
Other_CAMKK_CAMKK-Meta_CAMKK2_ST	Q96RR4	CAMKK2	Q96RR4	CAMKK2	S136	R139G	139	Missense	distal	3	no	15.127	19.115	EPSD	TCGA;ICGC;COSMIC	15.642	Gain
Other_CAMKK_CAMKK-Meta_CAMKK2_ST	Q96RR4	CAMKK2	Q96RR4	CAMKK2	T350	T350M	350	Missense	central	0	yes	18.401	0.000	EPSD	TCGA;COSMIC	15.642	Loss
Other_CAMKK_CAMKK-Meta_CAMKK2_ST	Q96RR4	CAMKK2	Q96RR4	CAMKK2	T350	L343H	343	Missense	distal	-7	no	18.401	18.840	EPSD	TCGA;ICGC;COSMIC	15.642	Up-regulation
Other_CAMKK_CAMKK-Meta_CAMKK2_ST	Q96RR4	CAMKK2	Q96RR4	CAMKK2	T350	E357D	357	Missense	distal	7	no	18.401	18.372	EPSD	TCGA;ICGC;COSMIC	15.642	Down-regulation
Other_CAMKK_CAMKK-Meta_CAMKK2_ST	Q96RR4	CAMKK2	Q96RR4	CAMKK2	S511	E507G	507	Missense	distal	-4	no	15.890	15.900	EPSD	TCGA;ICGC;COSMIC	15.642	Up-regulation
Other_CAMKK_CAMKK-Meta_CAMKK2_ST	Q96RR4	CAMKK2	Q96RR4	CAMKK2	S511	S509L	509	Missense	proximal	-2	no	15.890	17.426	EPSD	TCGA;ICGC;COSMIC	15.642	Up-regulation
Other_CAMKK_CAMKK-Meta_CAMKK2_ST	P54646	PRKAA2	Q96RR4	CAMKK2	T172	D166H	166	Missense	distal	-6	no	44.267	44.200	PhosphoSitePlus	TCGA;ICGC;COSMIC	15.642	Down-regulation
Other_CAMKK_CAMKK-Meta_CAMKK2_ST	P54646	PRKAA2	Q96RR4	CAMKK2	T172	S165L	165	Missense	distal	-7	no	44.267	42.266	PhosphoSitePlus	TCGA;ICGC;COSMIC	15.642	Down-regulation
Other_CAMKK_CAMKK-Meta_CAMKK2_ST	P54646	PRKAA2	Q96RR4	CAMKK2	T172	G175R	175	Missense	distal	3	no	44.267	40.279	PhosphoSitePlus	TCGA;ICGC;COSMIC	15.642	Down-regulation
Other_CAMKK_CAMKK-Meta_CAMKK2_ST	P54646	PRKAA2	Q96RR4	CAMKK2	T172	E168K	168	Missense	distal	-4	no	44.267	44.278	PhosphoSitePlus	TCGA;ICGC;COSMIC	15.642	Up-regulation
Other_CAMKK_CAMKK-Meta_CAMKK2_ST	P54646	PRKAA2	Q96RR4	CAMKK2	T172	P177L	177	Missense	distal	5	no	44.267	32.057	PhosphoSitePlus	TCGA;ICGC;COSMIC	15.642	Down-regulation
Other_CAMKK_CAMKK-Meta_CAMKK2_ST	P54646	PRKAA2	Q96RR4	CAMKK2	S173	D166H	166	Missense	distal	-7	no	16.125	15.169	EPSD	TCGA;ICGC;COSMIC	15.642	Loss
Other_CAMKK_CAMKK-Meta_CAMKK2_ST	P54646	PRKAA2	Q96RR4	CAMKK2	S173	G175R	175	Missense	proximal	2	no	16.125	14.208	EPSD	TCGA;ICGC;COSMIC	15.642	Loss
Other_CAMKK_CAMKK-Meta_CAMKK2_ST	P54646	PRKAA2	Q96RR4	CAMKK2	S173	E168K	168	Missense	distal	-5	no	16.125	15.414	EPSD	TCGA;ICGC;COSMIC	15.642	Loss
Other_CAMKK_CAMKK-Meta_CAMKK2_ST	P54646	PRKAA2	Q96RR4	CAMKK2	S173	P177L	177	Missense	distal	4	no	16.125	9.962	EPSD	TCGA;ICGC;COSMIC	15.642	Loss
Other_CAMKK_CAMKK-Meta_CAMKK2_ST	P54646	PRKAA2	Q96RR4	CAMKK2	S344	S348C	348	Missense	distal	4	no	22.143	19.130	EPSD	TCGA;ICGC;COSMIC	15.642	Down-regulation
Other_CAMKK_CAMKK-Meta_CAMKK2_ST	P54646	PRKAA2	Q96RR4	CAMKK2	S344	A343T	343	Missense	proximal	-1	no	22.143	21.997	EPSD	TCGA;ICGC;COSMIC;GDSC	15.642	Down-regulation
Other_CAMKK_CAMKK-Meta_CAMKK2_ST	P54646	PRKAA2	Q96RR4	CAMKK2	S345	S348C	348	Missense	distal	3	no	20.432	19.298	EPSD	TCGA;ICGC;COSMIC	15.642	Down-regulation
Other_CAMKK_CAMKK-Meta_CAMKK2_ST	P54646	PRKAA2	Q96RR4	CAMKK2	S345	M352I	352	Missense	distal	7	no	20.432	20.349	EPSD	TCGA;ICGC;COSMIC	15.642	Down-regulation
Other_CAMKK_CAMKK-Meta_CAMKK2_ST	P54646	PRKAA2	Q96RR4	CAMKK2	S345	A343T	343	Missense	proximal	-2	no	20.432	19.194	EPSD	TCGA;ICGC;COSMIC;GDSC	15.642	Down-regulation
Other_CAMKK_CAMKK-Meta_CAMKK2_ST	P54646	PRKAA2	Q96RR4	CAMKK2	S350	S348C	348	Missense	proximal	-2	no	17.660	18.946	EPSD	TCGA;ICGC;COSMIC	15.642	Up-regulation
Other_CAMKK_CAMKK-Meta_CAMKK2_ST	P54646	PRKAA2	Q96RR4	CAMKK2	S350	D354Y	354	Missense	distal	4	no	17.660	16.508	EPSD	TCGA;ICGC;COSMIC	15.642	Down-regulation
Other_CAMKK_CAMKK-Meta_CAMKK2_ST	P54646	PRKAA2	Q96RR4	CAMKK2	S350	A356V	356	Missense	distal	6	no	17.660	17.605	EPSD	TCGA;ICGC;COSMIC	15.642	Down-regulation
Other_CAMKK_CAMKK-Meta_CAMKK2_ST	P54646	PRKAA2	Q96RR4	CAMKK2	S350	M352I	352	Missense	proximal	2	no	17.660	17.396	EPSD	TCGA;ICGC;COSMIC	15.642	Down-regulation
Other_CAMKK_CAMKK-Meta_CAMKK2_ST	P54646	PRKAA2	Q96RR4	CAMKK2	S350	A343T	343	Missense	distal	-7	no	17.660	17.595	EPSD	TCGA;ICGC;COSMIC;GDSC	15.642	Down-regulation
Other_CAMKK_CAMKK-Meta_CAMKK2_ST	P54646	PRKAA2	Q96RR4	CAMKK2	S481	G482A	482	Missense	proximal	1	no	21.659	22.008	EPSD	TCGA;ICGC;COSMIC	15.642	Up-regulation
Other_CAMKK_CAMKK-Meta_CAMKK2_ST	P54646	PRKAA2	Q96RR4	CAMKK2	S501	T506A	506	Missense	distal	5	no	16.024	17.935	EPSD	TCGA;ICGC;COSMIC	15.642	Up-regulation
Other_CAMKK_CAMKK-Meta_CAMKK2_ST	P54646	PRKAA2	Q96RR4	CAMKK2	S501	P498L	498	Missense	distal	-3	no	16.024	16.103	EPSD	TCGA;ICGC;COSMIC	15.642	Up-regulation
Other_CAMKK_CAMKK-Meta_CAMKK2_ST	P54646	PRKAA2	Q96RR4	CAMKK2	S501	R497K	497	Missense	distal	-4	no	16.024	16.000	EPSD	TCGA;ICGC;COSMIC	15.642	Down-regulation
Other_CAMKK_CAMKK-Meta_CAMKK2_ST	P54646	PRKAA2	Q96RR4	CAMKK2	S501	S501C	501	Missense	central	0	yes	16.024	0.000	EPSD	TCGA;ICGC;COSMIC	15.642	Loss
Other_CAMKK_CAMKK-Meta_CAMKK2_ST	P31749	AKT1	Q96RR4	CAMKK2	S122	E116K	116	Missense	distal	-6	no	17.841	17.873	EPSD	TCGA;ICGC;COSMIC	15.642	Up-regulation
Other_CAMKK_CAMKK-Meta_CAMKK2_ST	P31749	AKT1	Q96RR4	CAMKK2	S122	R121W	121	Missense	proximal	-1	no	17.841	17.742	EPSD	TCGA;ICGC;COSMIC	15.642	Down-regulation
Other_CAMKK_CAMKK-Meta_CAMKK2_ST	P31749	AKT1	Q96RR4	CAMKK2	S129	E132K	132	Missense	distal	3	no	18.956	18.082	EPSD	TCGA;COSMIC	15.642	Down-regulation
Other_CAMKK_CAMKK-Meta_CAMKK2_ST	P31749	AKT1	Q96RR4	CAMKK2	S129	E133D	133	Missense	distal	4	no	18.956	19.322	EPSD	TCGA;ICGC;COSMIC	15.642	Up-regulation
Other_CAMKK_CAMKK-Meta_CAMKK2_ST	P31749	AKT1	Q96RR4	CAMKK2	S129	A131T	131	Missense	proximal	2	no	18.956	17.935	EPSD	TCGA;ICGC;COSMIC	15.642	Down-regulation
Other_CAMKK_CAMKK-Meta_CAMKK2_ST	P31749	AKT1	Q96RR4	CAMKK2	T308	G311D	311	Missense	distal	3	no	41.175	37.362	PhosphoSitePlus	TCGA;ICGC;COSMIC;GDSC;CCLE	15.642	Down-regulation
Other_CAMKK_CAMKK-Meta_CAMKK2_ST	P31749	AKT1	Q96RR4	CAMKK2	T450	I447V	447	Missense	distal	-3	no	15.693	15.704	EPSD	TCGA;ICGC;COSMIC	15.642	Up-regulation
TK_FGFR_FGFR1_Y	P11362	FGFR1	P11362	FGFR1	Y463	S461F	461	Missense	proximal	-2	no	8.511	8.682	EPSD;PhosphoSitePlus	TCGA;COSMIC	5.471	Up-regulation
TK_FGFR_FGFR1_Y	P11362	FGFR1	P11362	FGFR1	Y583	P587L	587	Missense	distal	4	no	7.952	7.644	EPSD;PhosphoSitePlus	TCGA;COSMIC	5.471	Down-regulation
TK_FGFR_FGFR1_Y	P11362	FGFR1	P11362	FGFR1	Y585	P587L	587	Missense	proximal	2	no	8.995	8.882	EPSD;PhosphoSitePlus	TCGA;COSMIC	5.471	Down-regulation
TK_FGFR_FGFR1_Y	P16144	ITGB4	P11362	FGFR1	Y1564	Y1564C	1564	Missense	central	0	yes	8.682	0.000	PhosphoSitePlus	TCGA;COSMIC	5.471	Loss
TK_FGFR_FGFR1_Y	P16144	ITGB4	P11362	FGFR1	Y1564	G1570S	1570	Missense	distal	6	no	8.682	8.687	PhosphoSitePlus	TCGA;COSMIC	5.471	Up-regulation
TK_FGFR_FGFR1_Y	Q9UBW7	ZMYM2	P11362	FGFR1	Y502	Q496E	496	Missense	distal	-6	no	7.710	7.728	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	5.471	Up-regulation
TK_FGFR_FGFR1_Y	Q9UBW7	ZMYM2	P11362	FGFR1	Y502	S497R	497	Missense	distal	-5	no	7.710	8.111	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	5.471	Up-regulation
TK_FGFR_FGFR1_Y	Q9UBW7	ZMYM2	P11362	FGFR1	Y557	I552T	552	Missense	distal	-5	no	7.516	4.909	EPSD;PhosphoSitePlus	TCGA;ICGC	5.471	Loss
TK_FGFR_FGFR1_Y	Q9UBW7	ZMYM2	P11362	FGFR1	Y557	P560L	560	Missense	distal	3	no	7.516	7.190	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	5.471	Down-regulation
TK_FGFR_FGFR1_Y	Q9UBW7	ZMYM2	P11362	FGFR1	Y605	Y605F	605	Missense	central	0	yes	10.063	0.000	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	5.471	Loss
TK_FGFR_FGFR1_Y	Q9UBW7	ZMYM2	P11362	FGFR1	Y605	C612Y	612	Missense	distal	7	no	10.063	9.914	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	5.471	Down-regulation
TK_FGFR_FGFR1_Y	Q9UBW7	ZMYM2	P11362	FGFR1	Y680	E686K	686	Missense	distal	6	no	8.296	8.300	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	5.471	Up-regulation
TK_FGFR_FGFR1_Y	Q9UBW7	ZMYM2	P11362	FGFR1	Y680	E682K	682	Missense	proximal	2	no	8.296	8.192	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	5.471	Down-regulation
TK_FGFR_FGFR1_Y	Q9UBW7	ZMYM2	P11362	FGFR1	Y683	E686K	686	Missense	distal	3	no	8.602	7.018	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	5.471	Down-regulation
TK_FGFR_FGFR1_Y	Q9UBW7	ZMYM2	P11362	FGFR1	Y683	K688T	688	Missense	distal	5	no	8.602	8.735	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	5.471	Up-regulation
TK_FGFR_FGFR1_Y	Q9UBW7	ZMYM2	P11362	FGFR1	Y683	E682K	682	Missense	proximal	-1	no	8.602	8.206	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	5.471	Down-regulation
TK_FGFR_FGFR1_Y	Q9UBW7	ZMYM2	P11362	FGFR1	Y729	N728Y	728	Missense	proximal	-1	no	8.607	8.261	EPSD;PhosphoSitePlus	TCGA	5.471	Down-regulation
TK_FGFR_FGFR1_Y	Q15118	PDK1	P11362	FGFR1	Y136	E130K	130	Missense	distal	-6	no	7.571	7.534	PhosphoSitePlus;EPSD	TCGA;ICGC;COSMIC	5.471	Down-regulation
TK_FGFR_FGFR1_Y	Q15118	PDK1	P11362	FGFR1	Y136	I135V	135	Missense	proximal	-1	no	7.571	6.530	PhosphoSitePlus;EPSD	TCGA;ICGC;COSMIC	5.471	Down-regulation
TK_FGFR_FGFR1_Y	Q15118	PDK1	P11362	FGFR1	Y243	E249K	249	Missense	distal	6	no	8.210	8.213	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	5.471	Up-regulation
TK_FGFR_FGFR1_Y	Q15118	PDK1	P11362	FGFR1	Y243	R237W	237	Missense	distal	-6	no	8.210	8.163	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	5.471	Down-regulation
TK_FGFR_FGFR1_Y	Q15118	PDK1	P11362	FGFR1	Y243	S247C	247	Missense	distal	4	no	8.210	6.890	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	5.471	Down-regulation
TK_FGFR_FGFR1_Y	Q15118	PDK1	P11362	FGFR1	Y244	E249K	249	Missense	distal	5	no	8.792	8.886	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	5.471	Up-regulation
TK_FGFR_FGFR1_Y	Q15118	PDK1	P11362	FGFR1	Y244	Y244C	244	Missense	central	0	yes	8.792	0.000	EPSD;PhosphoSitePlus	TCGA;ICGC	5.471	Loss
TK_FGFR_FGFR1_Y	Q15118	PDK1	P11362	FGFR1	Y244	R237W	237	Missense	distal	-7	no	8.792	8.831	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	5.471	Up-regulation
TK_FGFR_FGFR1_Y	Q15118	PDK1	P11362	FGFR1	Y244	S247C	247	Missense	distal	3	no	8.792	6.018	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	5.471	Down-regulation
TK_FGFR_FGFR1_Y	P24752	ACAT1	P11362	FGFR1	Y407	Y407C	407	Missense	central	0	yes	6.837	0.000	PhosphoSitePlus	TCGA;ICGC;COSMIC	5.471	Loss
AGC_GRK_BARK_GRK3_ST	P07550	ADRB2	P35626	GRK3	S246	E249Q	249	Missense	distal	3	no	14.215	14.016	EPSD	TCGA;ICGC;COSMIC	9.327	Down-regulation
AGC_GRK_BARK_GRK3_ST	P07550	ADRB2	P35626	GRK3	S246	E249K	249	Missense	distal	3	no	14.215	13.664	EPSD	TCGA;ICGC;COSMIC	9.327	Down-regulation
AGC_GRK_BARK_GRK3_ST	P07550	ADRB2	P35626	GRK3	S364	V368L	368	Missense	distal	4	no	17.055	16.902	EPSD	TCGA;ICGC;COSMIC	9.327	Down-regulation
AGC_GRK_BARK_GRK3_ST	P41146	OPRL1	P35626	GRK3	S164	R157C	157	Missense	distal	-7	no	12.344	10.188	EPSD	TCGA;ICGC;COSMIC	9.327	Down-regulation
AGC_GRK_BARK_GRK3_ST	P41146	OPRL1	P35626	GRK3	S164	V161I	161	Missense	distal	-3	no	12.344	12.226	EPSD	TCGA;ICGC;COSMIC;GDSC;CCLE	9.327	Down-regulation
AGC_GRK_BARK_GRK3_ST	P41146	OPRL1	P35626	GRK3	S164	T163K	163	Missense	proximal	-1	no	12.344	12.390	EPSD	TCGA;ICGC;COSMIC	9.327	Up-regulation
AGC_GRK_BARK_GRK3_ST	P41146	OPRL1	P35626	GRK3	S164	R162L	162	Missense	proximal	-2	no	12.344	9.057	EPSD	TCGA;ICGC;COSMIC	9.327	Loss
AGC_GRK_BARK_GRK3_ST	P41146	OPRL1	P35626	GRK3	S164	A167S	167	Missense	distal	3	no	12.344	12.532	EPSD	TCGA;ICGC;COSMIC	9.327	Up-regulation
AGC_GRK_BARK_GRK3_ST	P41146	OPRL1	P35626	GRK3	S164	A167V	167	Missense	distal	3	no	12.344	12.111	EPSD	TCGA;ICGC;COSMIC	9.327	Down-regulation
AGC_GRK_BARK_GRK3_ST	P41146	OPRL1	P35626	GRK3	S165	T163K	163	Missense	proximal	-2	no	11.421	11.262	EPSD	TCGA;ICGC;COSMIC	9.327	Down-regulation
AGC_GRK_BARK_GRK3_ST	P41146	OPRL1	P35626	GRK3	S165	R162L	162	Missense	distal	-3	no	11.421	10.261	EPSD	TCGA;ICGC;COSMIC	9.327	Down-regulation
AGC_GRK_BARK_GRK3_ST	P41146	OPRL1	P35626	GRK3	S165	A167S	167	Missense	proximal	2	no	11.421	11.517	EPSD	TCGA;ICGC;COSMIC	9.327	Up-regulation
AGC_GRK_BARK_GRK3_ST	P41146	OPRL1	P35626	GRK3	S165	A167V	167	Missense	proximal	2	no	11.421	11.239	EPSD	TCGA;ICGC;COSMIC	9.327	Down-regulation
AGC_SGK_SGK3_ST	Q96J02	ITCH	Q96BR1	SGK3	S4	Q7R	7	Missense	distal	3	no	0.751	2.414	EPSD	TCGA;ICGC;COSMIC	2.112	Gain
AGC_SGK_SGK3_ST	Q96J02	ITCH	Q96BR1	SGK3	S10	Q7R	7	Missense	distal	-3	no	-0.013	4.331	EPSD	TCGA;ICGC;COSMIC	2.112	Gain
AGC_SGK_SGK3_ST	Q96J02	ITCH	Q96BR1	SGK3	T214	S210Y	210	Missense	distal	-4	no	2.257	2.224	EPSD	TCGA;ICGC;COSMIC	2.112	Down-regulation
AGC_SGK_SGK3_ST	Q96J02	ITCH	Q96BR1	SGK3	T214	G220E	220	Missense	distal	6	no	2.257	2.264	EPSD	TCGA;ICGC;COSMIC	2.112	Up-regulation
AGC_SGK_SGK3_ST	Q96J02	ITCH	Q96BR1	SGK3	T214	R209I	209	Missense	distal	-5	no	2.257	0.541	EPSD	TCGA;ICGC	2.112	Loss
AGC_SGK_SGK3_ST	Q96J02	ITCH	Q96BR1	SGK3	T214	N219Y	219	Missense	distal	5	no	2.257	2.301	EPSD	TCGA;ICGC;COSMIC	2.112	Up-regulation
AGC_SGK_SGK3_ST	Q96J02	ITCH	Q96BR1	SGK3	T218	E225K	225	Missense	distal	7	no	4.879	4.884	EPSD	TCGA;ICGC;COSMIC	2.112	Up-regulation
AGC_SGK_SGK3_ST	Q96J02	ITCH	Q96BR1	SGK3	T218	G220E	220	Missense	proximal	2	no	4.879	4.575	EPSD	TCGA;ICGC;COSMIC	2.112	Down-regulation
AGC_SGK_SGK3_ST	Q96J02	ITCH	Q96BR1	SGK3	T218	N219Y	219	Missense	proximal	1	no	4.879	4.874	EPSD	TCGA;ICGC;COSMIC	2.112	Down-regulation
AGC_SGK_SGK3_ST	Q96J02	ITCH	Q96BR1	SGK3	S236	S240C	240	Missense	distal	4	no	4.554	4.514	EPSD	TCGA;ICGC;COSMIC	2.112	Down-regulation
AGC_SGK_SGK3_ST	Q96J02	ITCH	Q96BR1	SGK3	T263	T263P	263	Missense	central	0	yes	2.814	0.000	EPSD	TCGA;ICGC	2.112	Loss
AGC_SGK_SGK3_ST	Q96J02	ITCH	Q96BR1	SGK3	T263	P259S	259	Missense	distal	-4	no	2.814	2.847	EPSD	TCGA;ICGC;COSMIC	2.112	Up-regulation
AGC_SGK_SGK3_ST	Q96J02	ITCH	Q96BR1	SGK3	S450	D449N	449	Missense	proximal	-1	no	8.912	8.500	PhosphoSitePlus;EPSD	TCGA;ICGC;COSMIC	2.112	Down-regulation
AGC_SGK_SGK3_ST	Q96J02	ITCH	Q96BR1	SGK3	S450	D449Y	449	Missense	proximal	-1	no	8.912	8.398	PhosphoSitePlus;EPSD	TCGA;ICGC	2.112	Down-regulation
AGC_SGK_SGK3_ST	Q96J02	ITCH	Q96BR1	SGK3	T504	R510S	510	Missense	distal	6	no	4.318	4.243	EPSD	TCGA;ICGC;COSMIC	2.112	Down-regulation
AGC_SGK_SGK3_ST	Q96J02	ITCH	Q96BR1	SGK3	T504	R510H	510	Missense	distal	6	no	4.318	4.325	EPSD	TCGA;ICGC;COSMIC;CCLE	2.112	Up-regulation
AGC_SGK_SGK3_ST	Q96J02	ITCH	Q96BR1	SGK3	T505	R510S	510	Missense	distal	5	no	6.089	5.949	EPSD	TCGA;ICGC;COSMIC	2.112	Down-regulation
AGC_SGK_SGK3_ST	Q96J02	ITCH	Q96BR1	SGK3	T505	R510H	510	Missense	distal	5	no	6.089	5.992	EPSD	TCGA;ICGC;COSMIC;CCLE	2.112	Down-regulation
AGC_SGK_SGK3_ST	Q13045	FLII	Q96BR1	SGK3	S62	Q56R	56	Missense	distal	-6	no	2.302	2.353	EPSD	TCGA;ICGC;COSMIC	2.112	Up-regulation
AGC_SGK_SGK3_ST	Q13045	FLII	Q96BR1	SGK3	S62	T69I	69	Missense	distal	7	no	2.302	2.292	EPSD	TCGA;ICGC	2.112	Down-regulation
AGC_SGK_SGK3_ST	Q13045	FLII	Q96BR1	SGK3	S90	R87Q	87	Missense	distal	-3	no	3.839	-0.505	EPSD	TCGA;ICGC;COSMIC	2.112	Loss
AGC_SGK_SGK3_ST	Q13045	FLII	Q96BR1	SGK3	S406	G404V	404	Missense	proximal	-2	no	2.410	2.335	EPSD	TCGA;ICGC;COSMIC	2.112	Down-regulation
AGC_SGK_SGK3_ST	Q13045	FLII	Q96BR1	SGK3	S406	A403V	403	Missense	distal	-3	no	2.410	2.228	EPSD	TCGA;ICGC;COSMIC	2.112	Down-regulation
AGC_SGK_SGK3_ST	Q13045	FLII	Q96BR1	SGK3	S406	R401W	401	Missense	distal	-5	no	2.410	0.754	EPSD	TCGA;ICGC;CCLE	2.112	Loss
AGC_SGK_SGK3_ST	Q13045	FLII	Q96BR1	SGK3	S436	R431W	431	Missense	distal	-5	no	8.948	7.292	PhosphoSitePlus;EPSD	TCGA;COSMIC	2.112	Down-regulation
AGC_SGK_SGK3_ST	Q13045	FLII	Q96BR1	SGK3	S436	R432K	432	Missense	distal	-4	no	8.948	8.757	PhosphoSitePlus;EPSD	TCGA;COSMIC	2.112	Down-regulation
AGC_SGK_SGK3_ST	Q13045	FLII	Q96BR1	SGK3	S436	D440G	440	Missense	distal	4	no	8.948	8.913	PhosphoSitePlus;EPSD	TCGA	2.112	Down-regulation
AGC_SGK_SGK3_ST	Q13045	FLII	Q96BR1	SGK3	T670	A676V	676	Missense	distal	6	no	2.475	2.451	EPSD	TCGA;COSMIC	2.112	Down-regulation
AGC_SGK_SGK3_ST	Q13045	FLII	Q96BR1	SGK3	T818	L823P	823	Missense	distal	5	no	9.197	9.159	EPSD;PhosphoSitePlus	TCGA;COSMIC	2.112	Down-regulation
AGC_SGK_SGK3_ST	P49841	GSK3B	Q96BR1	SGK3	S35	G34S	34	Missense	proximal	-1	no	2.319	2.437	EPSD	TCGA;COSMIC	2.112	Up-regulation
AGC_SGK_SGK3_ST	P49841	GSK3B	Q96BR1	SGK3	S55	T59I	59	Missense	distal	4	no	2.133	2.154	EPSD	TCGA;ICGC;COSMIC	2.112	Up-regulation
AGC_SGK_SGK3_ST	P49841	GSK3B	Q96BR1	SGK3	S55	D49N	49	Missense	distal	-6	no	2.133	2.111	EPSD	TCGA;ICGC;COSMIC	2.112	Loss
AGC_SGK_SGK3_ST	P49841	GSK3B	Q96BR1	SGK3	S147	R148G	148	Missense	proximal	1	no	4.301	4.294	EPSD	TCGA;ICGC;COSMIC	2.112	Down-regulation
Atypical_PIKK_ATM_ATM_ST	Q9NVI1	FANCI	Q13315	ATM	S565	H568N	568	Missense	distal	3	no	13.688	13.665	EPSD	TCGA;ICGC;COSMIC	9.540	Down-regulation
Atypical_PIKK_ATM_ATM_ST	Q9NVI1	FANCI	Q13315	ATM	S629	F634L	634	Missense	distal	5	no	14.137	13.995	EPSD	TCGA;ICGC;COSMIC	9.540	Down-regulation
Atypical_PIKK_ATM_ATM_ST	Q9NVI1	FANCI	Q13315	ATM	S629	K632Q	632	Missense	distal	3	no	14.137	14.107	EPSD	TCGA;ICGC;COSMIC	9.540	Down-regulation
Atypical_PIKK_ATM_ATM_ST	Q9NVI1	FANCI	Q13315	ATM	T653	E648Q	648	Missense	distal	-5	no	10.521	10.553	EPSD	TCGA;ICGC;COSMIC	9.540	Up-regulation
Atypical_PIKK_ATM_ATM_ST	Q9NVI1	FANCI	Q13315	ATM	T653	S659C	659	Missense	distal	6	no	10.521	10.449	EPSD	TCGA;ICGC;COSMIC	9.540	Down-regulation
Atypical_PIKK_ATM_ATM_ST	Q9NVI1	FANCI	Q13315	ATM	T653	S659F	659	Missense	distal	6	no	10.521	10.445	EPSD	TCGA;ICGC;COSMIC	9.540	Down-regulation
Atypical_PIKK_ATM_ATM_ST	Q9NVI1	FANCI	Q13315	ATM	T653	D656N	656	Missense	distal	3	no	10.521	10.538	EPSD	TCGA;ICGC	9.540	Up-regulation
Atypical_PIKK_ATM_ATM_ST	Q9NVI1	FANCI	Q13315	ATM	S726	D728H	728	Missense	proximal	2	no	11.387	10.325	EPSD	TCGA;ICGC;COSMIC	9.540	Down-regulation
Atypical_PIKK_ATM_ATM_ST	Q9NVI1	FANCI	Q13315	ATM	S730	D728H	728	Missense	proximal	-2	no	16.945	16.816	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	9.540	Down-regulation
Atypical_PIKK_ATM_ATM_ST	Q9NVI1	FANCI	Q13315	ATM	S828	S834F	834	Missense	distal	6	no	9.870	9.794	EPSD	TCGA;ICGC;COSMIC	9.540	Down-regulation
Atypical_PIKK_ATM_ATM_ST	Q9NVI1	FANCI	Q13315	ATM	T952	R954I	954	Missense	proximal	2	no	10.846	11.160	EPSD	TCGA;ICGC	9.540	Up-regulation
Atypical_PIKK_ATM_ATM_ST	Q9NVI1	FANCI	Q13315	ATM	S1050	I1044L	1044	Missense	distal	-6	no	14.190	14.303	EPSD	TCGA;ICGC;COSMIC	9.540	Up-regulation
Atypical_PIKK_ATM_ATM_ST	Q9NVI1	FANCI	Q13315	ATM	S1050	R1047C	1047	Missense	distal	-3	no	14.190	13.618	EPSD	TCGA;ICGC;COSMIC	9.540	Down-regulation
Atypical_PIKK_ATM_ATM_ST	Q9NVI1	FANCI	Q13315	ATM	S1111	E1118Q	1118	Missense	distal	7	no	15.807	15.821	EPSD	TCGA;ICGC;COSMIC	9.540	Up-regulation
Atypical_PIKK_ATM_ATM_ST	Q9NVI1	FANCI	Q13315	ATM	S1111	G1108R	1108	Missense	distal	-3	no	15.807	16.269	EPSD	TCGA;ICGC;COSMIC	9.540	Up-regulation
Atypical_PIKK_ATM_ATM_ST	Q9NVI1	FANCI	Q13315	ATM	S1121	E1118Q	1118	Missense	distal	-3	no	15.858	15.982	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	9.540	Up-regulation
Atypical_PIKK_ATM_ATM_ST	Q9NVI1	FANCI	Q13315	ATM	S1121	S1120F	1120	Missense	proximal	-1	no	15.858	15.432	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	9.540	Down-regulation
Atypical_PIKK_ATM_ATM_ST	Q9NVI1	FANCI	Q13315	ATM	S1284	R1285Q	1285	Missense	proximal	1	no	9.085	15.737	EPSD	TCGA	9.540	Gain
Atypical_PIKK_ATM_ATM_ST	Q9NVI1	FANCI	Q13315	ATM	S1312	E1305K	1305	Missense	distal	-7	no	10.278	9.610	EPSD	TCGA;ICGC;COSMIC	9.540	Down-regulation
Atypical_PIKK_ATM_ATM_ST	Q9NVI1	FANCI	Q13315	ATM	S1312	T1310A	1310	Missense	proximal	-2	no	10.278	10.178	EPSD	TCGA;ICGC;COSMIC	9.540	Down-regulation
Atypical_PIKK_ATM_ATM_ST	Q9NVI1	FANCI	Q13315	ATM	S1312	E1307Q	1307	Missense	distal	-5	no	10.278	10.309	EPSD	TCGA;ICGC;COSMIC	9.540	Up-regulation
Atypical_PIKK_ATM_ATM_ST	O60934	NBN	Q13315	ATM	S278	D284G	284	Missense	distal	6	no	16.657	16.660	EPSD;PhosphoSitePlus	TCGA;COSMIC	9.540	Up-regulation
Atypical_PIKK_ATM_ATM_ST	O60934	NBN	Q13315	ATM	S278	T276A	276	Missense	proximal	-2	no	16.657	16.557	EPSD;PhosphoSitePlus	TCGA	9.540	Down-regulation
Atypical_PIKK_ATM_ATM_ST	O60934	NBN	Q13315	ATM	T337	P338L	338	Missense	proximal	1	no	9.859	8.304	EPSD	TCGA;COSMIC	9.540	Loss
Atypical_PIKK_ATM_ATM_ST	O60934	NBN	Q13315	ATM	T337	T337N	337	Missense	central	0	yes	9.859	0.000	EPSD	TCGA;COSMIC	9.540	Loss
Atypical_PIKK_ATM_ATM_ST	O60934	NBN	Q13315	ATM	T337	T337I	337	Missense	central	0	yes	9.859	0.000	EPSD	TCGA;COSMIC	9.540	Loss
Atypical_PIKK_ATM_ATM_ST	O60934	NBN	Q13315	ATM	S343	P338L	338	Missense	distal	-5	no	15.318	15.337	PhosphoSitePlus;EPSD	TCGA;COSMIC	9.540	Up-regulation
Atypical_PIKK_ATM_ATM_ST	O60934	NBN	Q13315	ATM	S343	T337N	337	Missense	distal	-6	no	15.318	15.271	PhosphoSitePlus;EPSD	TCGA;COSMIC	9.540	Down-regulation
Atypical_PIKK_ATM_ATM_ST	O60934	NBN	Q13315	ATM	S343	T337I	337	Missense	distal	-6	no	15.318	14.986	PhosphoSitePlus;EPSD	TCGA;COSMIC	9.540	Down-regulation
Atypical_PIKK_ATM_ATM_ST	O60934	NBN	Q13315	ATM	S397	K392Q	392	Missense	distal	-5	no	13.676	13.626	EPSD;PhosphoSitePlus	TCGA;COSMIC	9.540	Down-regulation
Atypical_PIKK_ATM_ATM_ST	O60934	NBN	Q13315	ATM	S447	S454F	454	Missense	distal	7	no	13.287	13.347	EPSD	TCGA;COSMIC	9.540	Up-regulation
Atypical_PIKK_ATM_ATM_ST	O60934	NBN	Q13315	ATM	S447	S447Y	447	Missense	central	0	yes	13.287	0.000	EPSD	TCGA;COSMIC	9.540	Loss
Atypical_PIKK_ATM_ATM_ST	O60934	NBN	Q13315	ATM	T493	S499L	499	Missense	distal	6	no	12.695	12.638	EPSD	TCGA;COSMIC	9.540	Down-regulation
Atypical_PIKK_ATM_ATM_ST	O60934	NBN	Q13315	ATM	S509	E510Q	510	Missense	proximal	1	no	7.372	13.269	EPSD	TCGA;COSMIC	9.540	Gain
Atypical_PIKK_ATM_ATM_ST	O60934	NBN	Q13315	ATM	S615	E610K	610	Missense	distal	-5	no	14.474	14.556	EPSD;PhosphoSitePlus	TCGA;COSMIC	9.540	Up-regulation
Atypical_PIKK_ATM_ATM_ST	O60934	NBN	Q13315	ATM	S615	E619K	619	Missense	distal	4	no	14.474	14.852	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	9.540	Up-regulation
Atypical_PIKK_ATM_ATM_ST	O60934	NBN	Q13315	ATM	S673	D678G	678	Missense	distal	5	no	9.535	9.626	EPSD	TCGA;COSMIC	9.540	Gain
Atypical_PIKK_ATM_ATM_ST	P78527	PRKDC	Q13315	ATM	S245	Q243H	243	Missense	proximal	-2	no	10.698	10.395	EPSD	TCGA;ICGC	9.540	Down-regulation
Atypical_PIKK_ATM_ATM_ST	P78527	PRKDC	Q13315	ATM	S503	E502K	502	Missense	proximal	-1	no	9.867	9.464	EPSD	TCGA;ICGC;COSMIC	9.540	Loss
Atypical_PIKK_ATM_ATM_ST	P78527	PRKDC	Q13315	ATM	S503	G500D	500	Missense	distal	-3	no	9.867	9.834	EPSD	TCGA;COSMIC	9.540	Down-regulation
Atypical_PIKK_ATM_ATM_ST	P78527	PRKDC	Q13315	ATM	S505	E502K	502	Missense	distal	-3	no	10.220	10.287	EPSD	TCGA;ICGC;COSMIC	9.540	Up-regulation
Atypical_PIKK_ATM_ATM_ST	P78527	PRKDC	Q13315	ATM	S505	G500D	500	Missense	distal	-5	no	10.220	9.955	EPSD	TCGA;COSMIC	9.540	Down-regulation
Atypical_PIKK_ATM_ATM_ST	P78527	PRKDC	Q13315	ATM	S876	S875F	875	Missense	proximal	-1	no	10.781	10.355	EPSD	TCGA;ICGC;COSMIC	9.540	Down-regulation
Atypical_PIKK_ATM_ATM_ST	P78527	PRKDC	Q13315	ATM	S876	L870I	870	Missense	distal	-6	no	10.781	10.669	EPSD	TCGA;ICGC;COSMIC	9.540	Down-regulation
Atypical_PIKK_ATM_ATM_ST	P78527	PRKDC	Q13315	ATM	S882	S875F	875	Missense	distal	-7	no	9.878	9.049	EPSD	TCGA;ICGC;COSMIC	9.540	Loss
Atypical_PIKK_ATM_ATM_ST	P78527	PRKDC	Q13315	ATM	S1162	V1169L	1169	Missense	distal	7	no	9.795	9.766	EPSD	TCGA;ICGC;COSMIC	9.540	Down-regulation
Atypical_PIKK_ATM_ATM_ST	P78527	PRKDC	Q13315	ATM	S1162	P1159S	1159	Missense	distal	-3	no	9.795	9.599	EPSD	TCGA;ICGC;COSMIC	9.540	Down-regulation
Atypical_PIKK_ATM_ATM_ST	P78527	PRKDC	Q13315	ATM	S3821	L3815P	3815	Missense	distal	-6	no	14.735	14.964	EPSD	TCGA;ICGC	9.540	Up-regulation
Atypical_PIKK_ATM_ATM_ST	Q99801	NKX3-1	Q13315	ATM	S48	D53H	53	Missense	distal	5	no	12.696	12.749	EPSD	TCGA;ICGC;COSMIC	9.540	Up-regulation
Atypical_PIKK_ATM_ATM_ST	Q99801	NKX3-1	Q13315	ATM	T134	T134I	134	Missense	central	0	yes	13.822	0.000	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	9.540	Loss
Atypical_PIKK_ATM_ATM_ST	Q99801	NKX3-1	Q13315	ATM	T134	H133P	133	Missense	proximal	-1	no	13.822	13.734	EPSD;PhosphoSitePlus	TCGA;COSMIC	9.540	Down-regulation
Atypical_PIKK_ATM_ATM_ST	Q99801	NKX3-1	Q13315	ATM	T134	R128Q	128	Missense	distal	-6	no	13.822	13.966	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	9.540	Up-regulation
Atypical_PIKK_ATM_ATM_ST	Q99801	NKX3-1	Q13315	ATM	T166	W171R	171	Missense	distal	5	no	14.014	13.991	PhosphoSitePlus;EPSD	TCGA;ICGC;COSMIC	9.540	Down-regulation
Atypical_PIKK_ATM_ATM_ST	Q12888	TP53BP1	Q13315	ATM	S294	L289R	289	Missense	distal	-5	no	11.772	11.825	EPSD	TCGA;COSMIC	9.540	Up-regulation
Atypical_PIKK_ATM_ATM_ST	Q12888	TP53BP1	Q13315	ATM	S452	S457C	457	Missense	distal	5	no	14.112	14.339	EPSD	TCGA;COSMIC	9.540	Up-regulation
Atypical_PIKK_ATM_ATM_ST	Q12888	TP53BP1	Q13315	ATM	T543	E546K	546	Missense	distal	3	no	13.539	13.828	EPSD	TCGA	9.540	Up-regulation
Atypical_PIKK_ATM_ATM_ST	Q12888	TP53BP1	Q13315	ATM	T548	E546K	546	Missense	proximal	-2	no	10.427	9.851	EPSD	TCGA	9.540	Down-regulation
Atypical_PIKK_ATM_ATM_ST	Q12888	TP53BP1	Q13315	ATM	S580	Q578H	578	Missense	proximal	-2	no	16.217	15.913	EPSD	TCGA;COSMIC	9.540	Down-regulation
Atypical_PIKK_ATM_ATM_ST	Q12888	TP53BP1	Q13315	ATM	S970	G976E	976	Missense	distal	6	no	11.215	11.259	EPSD	TCGA;COSMIC	9.540	Up-regulation
Atypical_PIKK_ATM_ATM_ST	Q12888	TP53BP1	Q13315	ATM	T1273	E1271K	1271	Missense	proximal	-2	no	9.816	9.241	EPSD	TCGA;COSMIC	9.540	Loss
Atypical_PIKK_ATM_ATM_ST	Q12888	TP53BP1	Q13315	ATM	S1317	S1311F	1311	Missense	distal	-6	no	10.076	9.545	EPSD	TCGA;COSMIC	9.540	Down-regulation
Atypical_PIKK_ATM_ATM_ST	Q12888	TP53BP1	Q13315	ATM	S1430	S1435P	1435	Missense	distal	5	no	10.427	10.609	EPSD	TCGA;COSMIC	9.540	Up-regulation
Atypical_PIKK_ATM_ATM_ST	Q12888	TP53BP1	Q13315	ATM	S1481	G1488V	1488	Missense	distal	7	no	10.215	10.222	EPSD	TCGA	9.540	Up-regulation
Atypical_PIKK_ATM_ATM_ST	Q12888	TP53BP1	Q13315	ATM	S1678	R1682W	1682	Missense	distal	4	no	11.099	11.243	EPSD	TCGA;COSMIC	9.540	Up-regulation
Atypical_PIKK_ATM_ATM_ST	Q12888	TP53BP1	Q13315	ATM	S1678	R1682Q	1682	Missense	distal	4	no	11.099	10.951	EPSD	TCGA;COSMIC	9.540	Down-regulation
Atypical_PIKK_ATM_ATM_ST	P08047	SP1	Q13315	ATM	S56	L61V	61	Missense	distal	5	no	15.449	15.496	PhosphoSitePlus;EPSD	TCGA;ICGC;COSMIC	9.540	Up-regulation
Atypical_PIKK_ATM_ATM_ST	P08047	SP1	Q13315	ATM	S56	S59F	59	Missense	distal	3	no	15.449	16.030	PhosphoSitePlus;EPSD	TCGA;ICGC;COSMIC	9.540	Up-regulation
Atypical_PIKK_ATM_ATM_ST	P08047	SP1	Q13315	ATM	S56	T49A	49	Missense	distal	-7	no	15.449	15.433	PhosphoSitePlus;EPSD	TCGA;ICGC	9.540	Down-regulation
Atypical_PIKK_ATM_ATM_ST	P08047	SP1	Q13315	ATM	S59	L61V	61	Missense	proximal	2	no	9.363	9.715	EPSD	TCGA;ICGC;COSMIC	9.540	Gain
Atypical_PIKK_ATM_ATM_ST	P08047	SP1	Q13315	ATM	S73	S69N	69	Missense	distal	-4	no	11.367	10.439	EPSD	TCGA;ICGC;COSMIC	9.540	Down-regulation
Atypical_PIKK_ATM_ATM_ST	P08047	SP1	Q13315	ATM	S73	C68R	68	Missense	distal	-5	no	11.367	11.350	EPSD	TCGA;ICGC;COSMIC	9.540	Down-regulation
Atypical_PIKK_ATM_ATM_ST	P08047	SP1	Q13315	ATM	S73	P74S	74	Missense	proximal	1	no	11.367	4.392	EPSD	TCGA;ICGC;COSMIC	9.540	Loss
Atypical_PIKK_ATM_ATM_ST	P08047	SP1	Q13315	ATM	S73	S78N	78	Missense	distal	5	no	11.367	11.342	EPSD	TCGA;ICGC;COSMIC	9.540	Down-regulation
Atypical_PIKK_ATM_ATM_ST	P08047	SP1	Q13315	ATM	S81	P74S	74	Missense	distal	-7	no	11.491	11.727	EPSD	TCGA;ICGC;COSMIC	9.540	Up-regulation
Atypical_PIKK_ATM_ATM_ST	P08047	SP1	Q13315	ATM	S81	S78N	78	Missense	distal	-3	no	11.491	11.464	EPSD	TCGA;ICGC;COSMIC	9.540	Down-regulation
Atypical_PIKK_ATM_ATM_ST	P08047	SP1	Q13315	ATM	S85	G89E	89	Missense	distal	4	no	13.102	12.675	EPSD	TCGA;ICGC;COSMIC	9.540	Down-regulation
Atypical_PIKK_ATM_ATM_ST	P08047	SP1	Q13315	ATM	S85	S78N	78	Missense	distal	-7	no	13.102	12.916	EPSD	TCGA;ICGC;COSMIC	9.540	Down-regulation
Atypical_PIKK_ATM_ATM_ST	P08047	SP1	Q13315	ATM	S588	D590E	590	Missense	proximal	2	no	10.857	10.988	EPSD	TCGA;ICGC;COSMIC	9.540	Up-regulation
Atypical_PIKK_ATM_ATM_ST	P08047	SP1	Q13315	ATM	S588	S588N	588	Missense	central	0	yes	10.857	0.000	EPSD	TCGA;ICGC;COSMIC	9.540	Loss
Atypical_PIKK_ATM_ATM_ST	P08047	SP1	Q13315	ATM	S617	D619H	619	Missense	proximal	2	no	9.931	8.869	EPSD	TCGA;ICGC;COSMIC	9.540	Loss
Atypical_PIKK_ATM_ATM_ST	P08047	SP1	Q13315	ATM	S617	D611N	611	Missense	distal	-6	no	9.931	9.842	EPSD	TCGA;ICGC;COSMIC	9.540	Down-regulation
Atypical_PIKK_ATM_ATM_ST	P08047	SP1	Q13315	ATM	S617	K623N	623	Missense	distal	6	no	9.931	9.941	EPSD	TCGA;ICGC	9.540	Up-regulation
Atypical_PIKK_ATM_ATM_ST	P08047	SP1	Q13315	ATM	S698	R697K	697	Missense	proximal	-1	no	9.855	10.037	EPSD	TCGA;ICGC;COSMIC	9.540	Up-regulation
Atypical_PIKK_ATM_ATM_ST	P08047	SP1	Q13315	ATM	T739	I744F	744	Missense	distal	5	no	9.655	9.751	EPSD	TCGA;ICGC;COSMIC	9.540	Up-regulation
Atypical_PIKK_ATM_ATM_ST	P08047	SP1	Q13315	ATM	T739	A742T	742	Missense	distal	3	no	9.655	9.679	EPSD	TCGA;ICGC	9.540	Up-regulation
Atypical_PIKK_ATM_ATM_ST	P08047	SP1	Q13315	ATM	T739	G736S	736	Missense	distal	-3	no	9.655	9.376	EPSD	TCGA;ICGC;COSMIC	9.540	Loss
Atypical_PIKK_ATM_ATM_ST	O95071	UBR5	Q13315	ATM	S117	E118Q	118	Missense	proximal	1	no	9.782	15.678	EPSD	TCGA;ICGC;COSMIC	9.540	Up-regulation
Atypical_PIKK_ATM_ATM_ST	O95071	UBR5	Q13315	ATM	S117	L120V	120	Missense	distal	3	no	9.782	9.843	EPSD	TCGA;ICGC;COSMIC	9.540	Up-regulation
Atypical_PIKK_ATM_ATM_ST	O95071	UBR5	Q13315	ATM	S117	L114I	114	Missense	distal	-3	no	9.782	10.242	EPSD	TCGA;ICGC	9.540	Up-regulation
Atypical_PIKK_ATM_ATM_ST	O95071	UBR5	Q13315	ATM	S174	Q175E	175	Missense	proximal	1	no	14.833	8.937	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	9.540	Loss
Atypical_PIKK_ATM_ATM_ST	O95071	UBR5	Q13315	ATM	S174	P181L	181	Missense	distal	7	no	14.833	14.834	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	9.540	Up-regulation
Atypical_PIKK_ATM_ATM_ST	O95071	UBR5	Q13315	ATM	S191	S191L	191	Missense	central	0	yes	14.811	0.000	PhosphoSitePlus;EPSD	TCGA;ICGC;COSMIC	9.540	Loss
Atypical_PIKK_ATM_ATM_ST	O95071	UBR5	Q13315	ATM	S191	P186S	186	Missense	distal	-5	no	14.811	14.807	PhosphoSitePlus;EPSD	TCGA;ICGC;COSMIC	9.540	Down-regulation
Atypical_PIKK_ATM_ATM_ST	O95071	UBR5	Q13315	ATM	S294	R295Q	295	Missense	proximal	1	no	6.952	13.603	EPSD	TCGA;ICGC;COSMIC;GDSC;CCLE	9.540	Gain
Atypical_PIKK_ATM_ATM_ST	O95071	UBR5	Q13315	ATM	T348	P353A	353	Missense	distal	5	no	9.869	9.735	EPSD	TCGA;COSMIC	9.540	Down-regulation
Atypical_PIKK_ATM_ATM_ST	O95071	UBR5	Q13315	ATM	S352	P353A	353	Missense	proximal	1	no	10.872	8.800	EPSD	TCGA;COSMIC	9.540	Loss
Atypical_PIKK_ATM_ATM_ST	O95071	UBR5	Q13315	ATM	S612	P610S	610	Missense	proximal	-2	no	10.640	10.877	EPSD	TCGA;COSMIC	9.540	Up-regulation
Atypical_PIKK_ATM_ATM_ST	O95071	UBR5	Q13315	ATM	S612	C617Y	617	Missense	distal	5	no	10.640	10.478	EPSD	TCGA;COSMIC	9.540	Down-regulation
Atypical_PIKK_ATM_ATM_ST	O95071	UBR5	Q13315	ATM	S612	G608S	608	Missense	distal	-4	no	10.640	11.428	EPSD	TCGA	9.540	Up-regulation
Atypical_PIKK_ATM_ATM_ST	O95071	UBR5	Q13315	ATM	S983	R984Q	984	Missense	proximal	1	no	7.605	14.257	EPSD	TCGA;COSMIC	9.540	Gain
Atypical_PIKK_ATM_ATM_ST	O95071	UBR5	Q13315	ATM	S1018	P1020H	1020	Missense	proximal	2	no	9.895	9.668	EPSD	TCGA	9.540	Down-regulation
Atypical_PIKK_ATM_ATM_ST	O95071	UBR5	Q13315	ATM	S1018	Q1014H	1014	Missense	distal	-4	no	9.895	9.660	EPSD	TCGA;COSMIC	9.540	Down-regulation
Atypical_PIKK_ATM_ATM_ST	O95071	UBR5	Q13315	ATM	S1018	P1020T	1020	Missense	proximal	2	no	9.895	10.088	EPSD	TCGA	9.540	Up-regulation
Atypical_PIKK_ATM_ATM_ST	O95071	UBR5	Q13315	ATM	S1347	I1343N	1343	Missense	distal	-4	no	13.700	13.483	EPSD	TCGA;ICGC;COSMIC	9.540	Down-regulation
Atypical_PIKK_ATM_ATM_ST	O95071	UBR5	Q13315	ATM	S1347	S1347L	1347	Missense	central	0	yes	13.700	0.000	EPSD	TCGA;ICGC;COSMIC	9.540	Loss
Atypical_PIKK_ATM_ATM_ST	O95071	UBR5	Q13315	ATM	S1347	P1353L	1353	Missense	distal	6	no	13.700	13.654	EPSD	TCGA;ICGC;COSMIC	9.540	Down-regulation
Atypical_PIKK_ATM_ATM_ST	O95071	UBR5	Q13315	ATM	S1375	R1379W	1379	Missense	distal	4	no	9.397	9.541	EPSD	TCGA;ICGC;COSMIC	9.540	Gain
Atypical_PIKK_ATM_ATM_ST	O95071	UBR5	Q13315	ATM	S1532	I1539V	1539	Missense	distal	7	no	15.306	15.323	EPSD;PhosphoSitePlus	TCGA;COSMIC	9.540	Up-regulation
Atypical_PIKK_ATM_ATM_ST	O95071	UBR5	Q13315	ATM	S1549	R1555W	1555	Missense	distal	6	no	16.098	16.066	EPSD	TCGA;COSMIC	9.540	Down-regulation
Atypical_PIKK_ATM_ATM_ST	O95071	UBR5	Q13315	ATM	S1549	R1547C	1547	Missense	proximal	-2	no	16.098	16.079	EPSD	TCGA;COSMIC	9.540	Down-regulation
Atypical_PIKK_ATM_ATM_ST	O95071	UBR5	Q13315	ATM	S1549	N1542H	1542	Missense	distal	-7	no	16.098	15.971	EPSD	TCGA;COSMIC	9.540	Down-regulation
Atypical_PIKK_ATM_ATM_ST	O95071	UBR5	Q13315	ATM	S1551	R1555W	1555	Missense	distal	4	no	14.645	14.789	EPSD	TCGA;COSMIC	9.540	Up-regulation
Atypical_PIKK_ATM_ATM_ST	O95071	UBR5	Q13315	ATM	S1551	R1547C	1547	Missense	distal	-4	no	14.645	13.882	EPSD	TCGA;COSMIC	9.540	Down-regulation
Atypical_PIKK_ATM_ATM_ST	O95071	UBR5	Q13315	ATM	S1551	D1558Y	1558	Missense	distal	7	no	14.645	14.671	EPSD	TCGA;COSMIC	9.540	Up-regulation
Atypical_PIKK_ATM_ATM_ST	O95071	UBR5	Q13315	ATM	S1679	S1677N	1677	Missense	proximal	-2	no	16.287	16.108	EPSD;PhosphoSitePlus	TCGA;COSMIC	9.540	Down-regulation
Atypical_PIKK_ATM_ATM_ST	O95071	UBR5	Q13315	ATM	S1679	D1683N	1683	Missense	distal	4	no	16.287	16.207	EPSD;PhosphoSitePlus	TCGA;COSMIC	9.540	Down-regulation
Atypical_PIKK_ATM_ATM_ST	O95071	UBR5	Q13315	ATM	S1679	S1674F	1674	Missense	distal	-5	no	16.287	16.611	EPSD;PhosphoSitePlus	TCGA;COSMIC	9.540	Up-regulation
Atypical_PIKK_ATM_ATM_ST	O95071	UBR5	Q13315	ATM	S1875	S1875F	1875	Missense	central	0	yes	12.796	0.000	EPSD	TCGA;COSMIC	9.540	Loss
Atypical_PIKK_ATM_ATM_ST	O95071	UBR5	Q13315	ATM	S1875	E1882K	1882	Missense	distal	7	no	12.796	12.823	EPSD	TCGA;COSMIC	9.540	Up-regulation
Atypical_PIKK_ATM_ATM_ST	O95071	UBR5	Q13315	ATM	S1875	H1870Y	1870	Missense	distal	-5	no	12.796	12.772	EPSD	TCGA;COSMIC	9.540	Down-regulation
Atypical_PIKK_ATM_ATM_ST	O95071	UBR5	Q13315	ATM	S2071	D2065N	2065	Missense	distal	-6	no	13.083	12.994	EPSD	TCGA;COSMIC	9.540	Down-regulation
Atypical_PIKK_ATM_ATM_ST	O95071	UBR5	Q13315	ATM	S2071	L2066F	2066	Missense	distal	-5	no	13.083	13.384	EPSD	TCGA;COSMIC	9.540	Up-regulation
Atypical_PIKK_ATM_ATM_ST	O95071	UBR5	Q13315	ATM	S2241	R2238T	2238	Missense	distal	-3	no	11.674	10.866	EPSD	TCGA;COSMIC	9.540	Down-regulation
Atypical_PIKK_ATM_ATM_ST	O95071	UBR5	Q13315	ATM	S2384	E2388G	2388	Missense	distal	4	no	11.328	11.755	EPSD	TCGA;ICGC;COSMIC	9.540	Up-regulation
Atypical_PIKK_ATM_ATM_ST	O95071	UBR5	Q13315	ATM	S2384	P2383S	2383	Missense	proximal	-1	no	11.328	11.620	EPSD	TCGA;ICGC	9.540	Up-regulation
Atypical_PIKK_ATM_ATM_ST	O95071	UBR5	Q13315	ATM	S2484	R2485Q	2485	Missense	proximal	1	no	8.455	15.107	EPSD	TCGA;COSMIC	9.540	Gain
Atypical_PIKK_ATM_ATM_ST	O95071	UBR5	Q13315	ATM	S2586	S2589A	2589	Missense	distal	3	no	14.138	14.194	EPSD;PhosphoSitePlus	TCGA;COSMIC	9.540	Up-regulation
Atypical_PIKK_ATM_ATM_ST	Q92945	KHSRP	Q13315	ATM	S125	P118S	118	Missense	distal	-7	no	13.930	14.166	EPSD	TCGA;ICGC;COSMIC	9.540	Up-regulation
Atypical_PIKK_ATM_ATM_ST	Q92945	KHSRP	Q13315	ATM	S181	C176F	176	Missense	distal	-5	no	10.909	11.139	EPSD	TCGA;ICGC;COSMIC	9.540	Up-regulation
Atypical_PIKK_ATM_ATM_ST	Q92945	KHSRP	Q13315	ATM	S274	T277A	277	Missense	distal	3	no	14.251	14.227	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	9.540	Down-regulation
Atypical_PIKK_ATM_ATM_ST	Q92945	KHSRP	Q13315	ATM	S274	T277M	277	Missense	distal	3	no	14.251	14.427	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC;CCLE	9.540	Up-regulation
Atypical_PIKK_ATM_ATM_ST	Q92945	KHSRP	Q13315	ATM	S461	G455E	455	Missense	distal	-6	no	9.259	9.648	EPSD	TCGA;ICGC;COSMIC	9.540	Gain
Atypical_PIKK_ATM_ATM_ST	Q92945	KHSRP	Q13315	ATM	S670	A676V	676	Missense	distal	6	no	15.038	15.008	PhosphoSitePlus;EPSD	TCGA;ICGC;COSMIC	9.540	Down-regulation
Atypical_PIKK_ATM_ATM_ST	Q96S59	RANBP9	Q13315	ATM	S181	R186W	186	Missense	distal	5	no	13.194	13.217	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	9.540	Up-regulation
Atypical_PIKK_ATM_ATM_ST	Q96S59	RANBP9	Q13315	ATM	S181	S181C	181	Missense	central	0	yes	13.194	0.000	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	9.540	Loss
Atypical_PIKK_ATM_ATM_ST	Q96S59	RANBP9	Q13315	ATM	S470	Q471E	471	Missense	proximal	1	no	14.208	8.311	EPSD	TCGA;ICGC;COSMIC	9.540	Loss
Atypical_PIKK_ATM_ATM_ST	Q96S59	RANBP9	Q13315	ATM	S470	Y474C	474	Missense	distal	4	no	14.208	14.414	EPSD	TCGA;ICGC;COSMIC	9.540	Up-regulation
Atypical_PIKK_ATM_ATM_ST	Q96S59	RANBP9	Q13315	ATM	S473	Q471E	471	Missense	proximal	-2	no	9.935	10.239	EPSD	TCGA;ICGC;COSMIC	9.540	Up-regulation
Atypical_PIKK_ATM_ATM_ST	Q96S59	RANBP9	Q13315	ATM	S473	Y474C	474	Missense	proximal	1	no	9.935	3.440	EPSD	TCGA;ICGC;COSMIC	9.540	Loss
Atypical_PIKK_ATM_ATM_ST	Q96S59	RANBP9	Q13315	ATM	S487	H490R	490	Missense	distal	3	no	11.402	11.364	EPSD	TCGA;ICGC;COSMIC	9.540	Down-regulation
Atypical_PIKK_ATM_ATM_ST	Q96S59	RANBP9	Q13315	ATM	S487	S489I	489	Missense	proximal	2	no	11.402	10.717	EPSD	TCGA;ICGC;COSMIC	9.540	Down-regulation
Atypical_PIKK_ATM_ATM_ST	Q96S59	RANBP9	Q13315	ATM	S489	H490R	490	Missense	proximal	1	no	1.406	9.663	EPSD	TCGA;ICGC;COSMIC	9.540	Gain
Atypical_PIKK_ATM_ATM_ST	Q96S59	RANBP9	Q13315	ATM	S550	S544N	544	Missense	distal	-6	no	14.458	14.342	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	9.540	Down-regulation
Atypical_PIKK_ATM_ATM_ST	Q96S59	RANBP9	Q13315	ATM	S603	R607C	607	Missense	distal	4	no	17.357	17.684	PhosphoSitePlus;EPSD	TCGA;ICGC;COSMIC	9.540	Up-regulation
Atypical_PIKK_ATM_ATM_ST	Q96S59	RANBP9	Q13315	ATM	S603	L605V	605	Missense	proximal	2	no	17.357	17.708	PhosphoSitePlus;EPSD	TCGA;ICGC;COSMIC	9.540	Up-regulation
Atypical_PIKK_ATM_ATM_ST	Q96S59	RANBP9	Q13315	ATM	S603	E597K	597	Missense	distal	-6	no	17.357	17.056	PhosphoSitePlus;EPSD	TCGA;ICGC;COSMIC	9.540	Down-regulation
Atypical_PIKK_ATM_ATM_ST	Q96S59	RANBP9	Q13315	ATM	S613	R607C	607	Missense	distal	-6	no	12.326	12.127	EPSD	TCGA;ICGC;COSMIC	9.540	Down-regulation
Atypical_PIKK_ATM_ATM_ST	Q96S59	RANBP9	Q13315	ATM	S613	A615V	615	Missense	proximal	2	no	12.326	12.017	EPSD	TCGA;ICGC;COSMIC	9.540	Down-regulation
Atypical_PIKK_ATM_ATM_ST	Q92547	TOPBP1	Q13315	ATM	S301	D307N	307	Missense	distal	6	no	16.182	16.194	EPSD	TCGA;ICGC;COSMIC	9.540	Up-regulation
Atypical_PIKK_ATM_ATM_ST	Q92547	TOPBP1	Q13315	ATM	S492	S499F	499	Missense	distal	7	no	16.145	16.205	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	9.540	Up-regulation
Atypical_PIKK_ATM_ATM_ST	Q92547	TOPBP1	Q13315	ATM	S554	K556N	556	Missense	proximal	2	no	15.307	15.486	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	9.540	Up-regulation
Atypical_PIKK_ATM_ATM_ST	Q92547	TOPBP1	Q13315	ATM	S554	L561V	561	Missense	distal	7	no	15.307	15.336	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	9.540	Up-regulation
Atypical_PIKK_ATM_ATM_ST	Q92547	TOPBP1	Q13315	ATM	S554	V560A	560	Missense	distal	6	no	15.307	15.337	EPSD;PhosphoSitePlus	TCGA;ICGC	9.540	Up-regulation
Atypical_PIKK_ATM_ATM_ST	Q92547	TOPBP1	Q13315	ATM	S747	T742I	742	Missense	distal	-5	no	11.372	11.575	EPSD	TCGA;ICGC	9.540	Up-regulation
Atypical_PIKK_ATM_ATM_ST	Q92547	TOPBP1	Q13315	ATM	S853	P859L	859	Missense	distal	6	no	14.550	14.504	EPSD;PhosphoSitePlus	TCGA;ICGC	9.540	Down-regulation
Atypical_PIKK_ATM_ATM_ST	Q92547	TOPBP1	Q13315	ATM	S864	V866F	866	Missense	proximal	2	no	9.733	9.147	EPSD	TCGA;ICGC;COSMIC	9.540	Loss
Atypical_PIKK_ATM_ATM_ST	Q92547	TOPBP1	Q13315	ATM	S864	T861M	861	Missense	distal	-3	no	9.733	10.156	EPSD	TCGA;ICGC;COSMIC	9.540	Up-regulation
Atypical_PIKK_ATM_ATM_ST	Q92547	TOPBP1	Q13315	ATM	S864	P859L	859	Missense	distal	-5	no	9.733	9.752	EPSD	TCGA;ICGC	9.540	Up-regulation
Atypical_PIKK_ATM_ATM_ST	Q92547	TOPBP1	Q13315	ATM	S888	Q890E	890	Missense	proximal	2	no	9.144	9.957	EPSD	TCGA;ICGC;COSMIC	9.540	Gain
Atypical_PIKK_ATM_ATM_ST	Q92547	TOPBP1	Q13315	ATM	S1002	R1008W	1008	Missense	distal	6	no	9.626	9.594	EPSD	TCGA;ICGC;COSMIC	9.540	Down-regulation
Atypical_PIKK_ATM_ATM_ST	Q92547	TOPBP1	Q13315	ATM	T1062	G1059A	1059	Missense	distal	-3	no	13.737	13.014	PhosphoSitePlus;EPSD	TCGA;ICGC;COSMIC	9.540	Down-regulation
Atypical_PIKK_ATM_ATM_ST	Q92547	TOPBP1	Q13315	ATM	S1138	E1141Q	1141	Missense	distal	3	no	13.698	13.957	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	9.540	Up-regulation
Atypical_PIKK_ATM_ATM_ST	Q92547	TOPBP1	Q13315	ATM	S1138	D1132G	1132	Missense	distal	-6	no	13.698	13.523	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	9.540	Down-regulation
Atypical_PIKK_ATM_ATM_ST	Q92547	TOPBP1	Q13315	ATM	S1504	L1503F	1503	Missense	proximal	-1	no	14.251	13.959	EPSD	TCGA	9.540	Down-regulation
Atypical_PIKK_ATM_ATM_ST	O94916	NFAT5	Q13315	ATM	T631	T631K	631	Missense	central	0	yes	14.850	0.000	EPSD	TCGA	9.540	Loss
Atypical_PIKK_ATM_ATM_ST	P12956	XRCC6	Q13315	ATM	T10	E11Q	11	Missense	proximal	1	no	4.668	10.565	EPSD	TCGA;ICGC;COSMIC	9.540	Gain
Atypical_PIKK_ATM_ATM_ST	P12956	XRCC6	Q13315	ATM	S51	E54K	54	Missense	distal	3	no	15.886	16.175	EPSD	TCGA;ICGC;COSMIC	9.540	Up-regulation
Atypical_PIKK_ATM_ATM_ST	P12956	XRCC6	Q13315	ATM	S51	M48I	48	Missense	distal	-3	no	15.886	16.201	EPSD	TCGA;ICGC;COSMIC	9.540	Up-regulation
Atypical_PIKK_ATM_ATM_ST	P12956	XRCC6	Q13315	ATM	S319	T316I	316	Missense	distal	-3	no	12.037	12.774	EPSD	TCGA;ICGC;COSMIC	9.540	Up-regulation
Atypical_PIKK_ATM_ATM_ST	P12956	XRCC6	Q13315	ATM	S319	D315N	315	Missense	distal	-4	no	12.037	11.113	EPSD	TCGA;ICGC;COSMIC	9.540	Down-regulation
Atypical_PIKK_ATM_ATM_ST	P12956	XRCC6	Q13315	ATM	S319	S314R	314	Missense	distal	-5	no	12.037	12.113	EPSD	TCGA;ICGC;COSMIC	9.540	Up-regulation
Atypical_PIKK_ATM_ATM_ST	P12956	XRCC6	Q13315	ATM	T334	K331N	331	Missense	distal	-3	no	9.965	10.031	EPSD	TCGA;ICGC;COSMIC;GDSC;CCLE	9.540	Up-regulation
Atypical_PIKK_ATM_ATM_ST	P12956	XRCC6	Q13315	ATM	T507	A513V	513	Missense	distal	6	no	10.243	10.212	EPSD	TCGA;ICGC;COSMIC	9.540	Down-regulation
Atypical_PIKK_ATM_ATM_ST	P12956	XRCC6	Q13315	ATM	T507	A513T	513	Missense	distal	6	no	10.243	10.226	EPSD	TCGA;GDSC	9.540	Down-regulation
Atypical_PIKK_ATM_ATM_ST	P12956	XRCC6	Q13315	ATM	S550	S550P	550	Missense	central	0	yes	9.837	0.000	EPSD	TCGA;ICGC	9.540	Loss
Atypical_PIKK_ATM_ATM_ST	P12956	XRCC6	Q13315	ATM	S560	E558Q	558	Missense	proximal	-2	no	11.355	11.050	EPSD	TCGA;ICGC;COSMIC	9.540	Down-regulation
Atypical_PIKK_ATM_ATM_ST	P12956	XRCC6	Q13315	ATM	S560	H567R	567	Missense	distal	7	no	11.355	11.361	EPSD	TCGA;ICGC;COSMIC	9.540	Up-regulation
Atypical_PIKK_ATM_ATM_ST	Q96SD1	DCLRE1C	Q13315	ATM	T91	S84C	84	Missense	distal	-7	no	12.041	11.367	EPSD	TCGA;COSMIC	9.540	Down-regulation
Atypical_PIKK_ATM_ATM_ST	Q96SD1	DCLRE1C	Q13315	ATM	T91	E86A	86	Missense	distal	-5	no	12.041	12.199	EPSD	TCGA;ICGC	9.540	Up-regulation
Atypical_PIKK_ATM_ATM_ST	Q96SD1	DCLRE1C	Q13315	ATM	T251	R249C	249	Missense	proximal	-2	no	11.244	11.225	EPSD	TCGA;COSMIC	9.540	Down-regulation
Atypical_PIKK_ATM_ATM_ST	Q96SD1	DCLRE1C	Q13315	ATM	T251	C256F	256	Missense	distal	5	no	11.244	11.324	EPSD	TCGA;COSMIC	9.540	Up-regulation
Atypical_PIKK_ATM_ATM_ST	Q96SD1	DCLRE1C	Q13315	ATM	T251	Q252H	252	Missense	proximal	1	no	11.244	-3.665	EPSD	TCGA;COSMIC	9.540	Loss
Atypical_PIKK_ATM_ATM_ST	Q96SD1	DCLRE1C	Q13315	ATM	T251	R249H	249	Missense	proximal	-2	no	11.244	11.260	EPSD	TCGA;COSMIC	9.540	Up-regulation
Atypical_PIKK_ATM_ATM_ST	Q96SD1	DCLRE1C	Q13315	ATM	T251	R257Q	257	Missense	distal	6	no	11.244	11.240	EPSD	TCGA;COSMIC	9.540	Down-regulation
Atypical_PIKK_ATM_ATM_ST	Q96SD1	DCLRE1C	Q13315	ATM	S503	N496S	496	Missense	distal	-7	no	12.034	12.221	PhosphoSitePlus;EPSD	TCGA	9.540	Up-regulation
Atypical_PIKK_ATM_ATM_ST	Q96SD1	DCLRE1C	Q13315	ATM	S503	S509F	509	Missense	distal	6	no	12.034	11.958	PhosphoSitePlus;EPSD	TCGA;COSMIC	9.540	Down-regulation
Atypical_PIKK_ATM_ATM_ST	Q96SD1	DCLRE1C	Q13315	ATM	S516	T511K	511	Missense	distal	-5	no	18.674	18.679	EPSD;PhosphoSitePlus	TCGA	9.540	Up-regulation
Atypical_PIKK_ATM_ATM_ST	Q96SD1	DCLRE1C	Q13315	ATM	S516	T511P	511	Missense	distal	-5	no	18.674	18.766	EPSD;PhosphoSitePlus	TCGA	9.540	Up-regulation
Atypical_PIKK_ATM_ATM_ST	Q96SD1	DCLRE1C	Q13315	ATM	S516	S509F	509	Missense	distal	-7	no	18.674	17.845	EPSD;PhosphoSitePlus	TCGA;COSMIC	9.540	Down-regulation
Atypical_PIKK_ATM_ATM_ST	Q96SD1	DCLRE1C	Q13315	ATM	S516	L521F	521	Missense	distal	5	no	18.674	18.816	EPSD;PhosphoSitePlus	TCGA;COSMIC	9.540	Up-regulation
Atypical_PIKK_ATM_ATM_ST	Q96SD1	DCLRE1C	Q13315	ATM	S518	T511K	511	Missense	distal	-7	no	12.901	12.670	EPSD	TCGA	9.540	Down-regulation
Atypical_PIKK_ATM_ATM_ST	Q96SD1	DCLRE1C	Q13315	ATM	S518	T511P	511	Missense	distal	-7	no	12.901	12.746	EPSD	TCGA	9.540	Down-regulation
Atypical_PIKK_ATM_ATM_ST	Q96SD1	DCLRE1C	Q13315	ATM	S518	L521F	521	Missense	distal	3	no	12.901	13.201	EPSD	TCGA;COSMIC	9.540	Up-regulation
Atypical_PIKK_ATM_ATM_ST	Q96SD1	DCLRE1C	Q13315	ATM	S534	T530I	530	Missense	distal	-4	no	15.088	14.760	EPSD	TCGA;COSMIC	9.540	Down-regulation
Atypical_PIKK_ATM_ATM_ST	Q96SD1	DCLRE1C	Q13315	ATM	S534	S537F	537	Missense	distal	3	no	15.088	15.670	EPSD	TCGA;COSMIC	9.540	Up-regulation
Atypical_PIKK_ATM_ATM_ST	Q96SD1	DCLRE1C	Q13315	ATM	S538	S537F	537	Missense	proximal	-1	no	13.667	13.240	EPSD	TCGA;COSMIC	9.540	Down-regulation
Atypical_PIKK_ATM_ATM_ST	Q96SD1	DCLRE1C	Q13315	ATM	S548	S548N	548	Missense	central	0	yes	12.812	0.000	EPSD	TCGA;COSMIC	9.540	Loss
Atypical_PIKK_ATM_ATM_ST	Q96SD1	DCLRE1C	Q13315	ATM	S553	S548N	548	Missense	distal	-5	no	16.420	16.392	EPSD	TCGA;COSMIC	9.540	Down-regulation
Atypical_PIKK_ATM_ATM_ST	Q96SD1	DCLRE1C	Q13315	ATM	S553	S548T	548	Missense	distal	-5	no	16.420	16.331	EPSD	TCGA;COSMIC	9.540	Down-regulation
Atypical_PIKK_ATM_ATM_ST	Q96SD1	DCLRE1C	Q13315	ATM	S553	D556N	556	Missense	distal	3	no	16.420	16.437	EPSD	TCGA;COSMIC	9.540	Up-regulation
Atypical_PIKK_ATM_ATM_ST	Q96SD1	DCLRE1C	Q13315	ATM	S553	D556G	556	Missense	distal	3	no	16.420	16.367	EPSD	TCGA;COSMIC	9.540	Down-regulation
Atypical_PIKK_ATM_ATM_ST	Q96SD1	DCLRE1C	Q13315	ATM	S562	D556N	556	Missense	distal	-6	no	15.649	15.560	EPSD	TCGA;COSMIC	9.540	Down-regulation
Atypical_PIKK_ATM_ATM_ST	Q96SD1	DCLRE1C	Q13315	ATM	S562	D556G	556	Missense	distal	-6	no	15.649	15.474	EPSD	TCGA;COSMIC	9.540	Down-regulation
Atypical_PIKK_ATM_ATM_ST	Q96SD1	DCLRE1C	Q13315	ATM	S645	N638T	638	Missense	distal	-7	no	13.341	13.446	EPSD;PhosphoSitePlus	TCGA;COSMIC	9.540	Up-regulation
Atypical_PIKK_ATM_ATM_ST	Q7LG56	RRM2B	Q13315	ATM	S20	E24K	24	Missense	distal	4	no	9.872	10.249	EPSD	TCGA;ICGC;COSMIC	9.540	Up-regulation
Atypical_PIKK_ATM_ATM_ST	Q7LG56	RRM2B	Q13315	ATM	S20	S20L	20	Missense	central	0	yes	9.872	0.000	EPSD	TCGA;ICGC;COSMIC	9.540	Loss
Atypical_PIKK_ATM_ATM_ST	Q7LG56	RRM2B	Q13315	ATM	S25	E24K	24	Missense	proximal	-1	no	10.055	9.652	EPSD	TCGA;ICGC;COSMIC	9.540	Down-regulation
Atypical_PIKK_ATM_ATM_ST	Q7LG56	RRM2B	Q13315	ATM	S25	S20L	20	Missense	distal	-5	no	10.055	10.078	EPSD	TCGA;ICGC;COSMIC	9.540	Up-regulation
Atypical_PIKK_ATM_ATM_ST	Q7LG56	RRM2B	Q13315	ATM	S72	P76T	76	Missense	distal	4	no	12.087	12.052	PhosphoSitePlus	TCGA;COSMIC	9.540	Down-regulation
Atypical_PIKK_ATM_ATM_ST	Q7LG56	RRM2B	Q13315	ATM	S72	D70Y	70	Missense	proximal	-2	no	12.087	12.216	PhosphoSitePlus	TCGA;COSMIC	9.540	Up-regulation
Atypical_PIKK_ATM_ATM_ST	Q7LG56	RRM2B	Q13315	ATM	S72	H77R	77	Missense	distal	5	no	12.087	12.113	PhosphoSitePlus	TCGA;COSMIC	9.540	Up-regulation
Atypical_PIKK_ATM_ATM_ST	Q7LG56	RRM2B	Q13315	ATM	S329	R327Q	327	Missense	proximal	-2	no	11.121	11.439	EPSD	TCGA;COSMIC	9.540	Up-regulation
Atypical_PIKK_ATM_ATM_ST	Q9H2K8	TAOK3	Q13315	ATM	S173	F178C	178	Missense	distal	5	no	10.257	10.177	EPSD	TCGA;ICGC;COSMIC	9.540	Down-regulation
Atypical_PIKK_ATM_ATM_ST	Q9H2K8	TAOK3	Q13315	ATM	S173	A175V	175	Missense	proximal	2	no	10.257	9.948	EPSD	TCGA;ICGC;COSMIC	9.540	Down-regulation
Atypical_PIKK_ATM_ATM_ST	Q9H2K8	TAOK3	Q13315	ATM	S173	A172V	172	Missense	proximal	-1	no	10.257	9.994	EPSD	TCGA;ICGC;COSMIC	9.540	Down-regulation
Atypical_PIKK_ATM_ATM_ST	Q9H2K8	TAOK3	Q13315	ATM	S324	G319R	319	Missense	distal	-5	no	14.238	14.259	EPSD	TCGA;ICGC;COSMIC	9.540	Up-regulation
Atypical_PIKK_ATM_ATM_ST	Q9H2K8	TAOK3	Q13315	ATM	S336	D342Y	342	Missense	distal	6	no	10.879	10.860	EPSD	TCGA;ICGC;COSMIC	9.540	Down-regulation
Atypical_PIKK_ATM_ATM_ST	Q9H2K8	TAOK3	Q13315	ATM	S336	S343G	343	Missense	distal	7	no	10.879	10.920	EPSD	TCGA;ICGC;COSMIC	9.540	Up-regulation
Atypical_PIKK_ATM_ATM_ST	Q9H2K8	TAOK3	Q13315	ATM	S424	R430G	430	Missense	distal	6	no	13.670	13.669	EPSD	TCGA;ICGC;COSMIC	9.540	Down-regulation
Atypical_PIKK_ATM_ATM_ST	Q9H2K8	TAOK3	Q13315	ATM	S551	I558M	558	Missense	distal	7	no	14.004	14.006	EPSD;PhosphoSitePlus	TCGA;COSMIC	9.540	Up-regulation
Atypical_PIKK_ATM_ATM_ST	Q9H2K8	TAOK3	Q13315	ATM	S551	T547P	547	Missense	distal	-4	no	14.004	13.717	EPSD;PhosphoSitePlus	TCGA	9.540	Down-regulation
Atypical_PIKK_ATM_ATM_ST	Q9H2K8	TAOK3	Q13315	ATM	S782	E789D	789	Missense	distal	7	no	14.981	14.993	EPSD	TCGA;COSMIC	9.540	Up-regulation
Atypical_PIKK_ATM_ATM_ST	Q9H2K8	TAOK3	Q13315	ATM	S782	E778Q	778	Missense	distal	-4	no	14.981	14.257	EPSD	TCGA;COSMIC	9.540	Down-regulation
Atypical_PIKK_ATM_ATM_ST	Q9H2K8	TAOK3	Q13315	ATM	S782	A784V	784	Missense	proximal	2	no	14.981	14.672	EPSD	TCGA;COSMIC	9.540	Down-regulation
Atypical_PIKK_ATM_ATM_ST	Q96RU2	USP28	Q13315	ATM	S249	R247Q	247	Missense	proximal	-2	no	9.238	9.556	EPSD	TCGA;COSMIC	9.540	Gain
Atypical_PIKK_ATM_ATM_ST	Q96RU2	USP28	Q13315	ATM	S375	R369I	369	Missense	distal	-6	no	11.657	11.437	EPSD	TCGA;COSMIC	9.540	Down-regulation
Atypical_PIKK_ATM_ATM_ST	Q96RU2	USP28	Q13315	ATM	S375	F370S	370	Missense	distal	-5	no	11.657	11.334	EPSD	TCGA	9.540	Down-regulation
Atypical_PIKK_ATM_ATM_ST	Q96RU2	USP28	Q13315	ATM	S375	P379A	379	Missense	distal	4	no	11.657	11.187	EPSD	TCGA;COSMIC	9.540	Down-regulation
Atypical_PIKK_ATM_ATM_ST	Q96RU2	USP28	Q13315	ATM	S375	F372C	372	Missense	distal	-3	no	11.657	10.753	EPSD	TCGA;COSMIC	9.540	Down-regulation
Atypical_PIKK_ATM_ATM_ST	Q96RU2	USP28	Q13315	ATM	S504	S508F	508	Missense	distal	4	no	10.400	11.228	EPSD	TCGA;COSMIC	9.540	Up-regulation
Atypical_PIKK_ATM_ATM_ST	Q96RU2	USP28	Q13315	ATM	S504	P510S	510	Missense	distal	6	no	10.400	10.411	EPSD	TCGA	9.540	Up-regulation
Atypical_PIKK_ATM_ATM_ST	Q96RU2	USP28	Q13315	ATM	S504	D507N	507	Missense	distal	3	no	10.400	10.417	EPSD	TCGA	9.540	Up-regulation
Atypical_PIKK_ATM_ATM_ST	Q96RU2	USP28	Q13315	ATM	S713	S714P	714	Missense	proximal	1	no	6.578	13.553	EPSD	TCGA	9.540	Gain
Atypical_PIKK_ATM_ATM_ST	Q96RU2	USP28	Q13315	ATM	S714	S718C	718	Missense	distal	4	no	16.349	16.859	EPSD;PhosphoSitePlus	TCGA	9.540	Up-regulation
Atypical_PIKK_ATM_ATM_ST	Q96RU2	USP28	Q13315	ATM	S714	S714P	714	Missense	central	0	yes	16.349	0.000	EPSD;PhosphoSitePlus	TCGA	9.540	Loss
Atypical_PIKK_ATM_ATM_ST	Q96RU2	USP28	Q13315	ATM	S720	S718C	718	Missense	proximal	-2	no	16.886	16.425	EPSD;PhosphoSitePlus	TCGA	9.540	Down-regulation
Atypical_PIKK_ATM_ATM_ST	Q96RU2	USP28	Q13315	ATM	S720	S714P	714	Missense	distal	-6	no	16.886	16.827	EPSD;PhosphoSitePlus	TCGA	9.540	Down-regulation
Atypical_PIKK_ATM_ATM_ST	Q96RU2	USP28	Q13315	ATM	S856	D852Y	852	Missense	distal	-4	no	11.522	10.425	EPSD	TCGA;COSMIC	9.540	Down-regulation
Atypical_PIKK_ATM_ATM_ST	Q96RU2	USP28	Q13315	ATM	S856	N854K	854	Missense	proximal	-2	no	11.522	11.306	EPSD	TCGA;COSMIC	9.540	Down-regulation
Atypical_PIKK_ATM_ATM_ST	Q96RU2	USP28	Q13315	ATM	S1053	R1060L	1060	Missense	distal	7	no	9.924	9.908	EPSD	TCGA;COSMIC	9.540	Down-regulation
Atypical_PIKK_ATM_ATM_ST	Q96RU2	USP28	Q13315	ATM	S1053	Y1055C	1055	Missense	proximal	2	no	9.924	9.531	EPSD	TCGA;COSMIC	9.540	Loss
Atypical_PIKK_ATM_ATM_ST	Q96RU2	USP28	Q13315	ATM	S1053	P1047Q	1047	Missense	distal	-6	no	9.924	9.946	EPSD	TCGA;COSMIC	9.540	Up-regulation
Atypical_PIKK_ATM_ATM_ST	Q96RU2	USP28	Q13315	ATM	S1053	S1053Y	1053	Missense	central	0	yes	9.924	0.000	EPSD	TCGA;COSMIC	9.540	Loss
Atypical_PIKK_ATM_ATM_ST	Q96RU2	USP28	Q13315	ATM	S1053	R1050Q	1050	Missense	distal	-3	no	9.924	9.149	EPSD	TCGA;COSMIC	9.540	Loss
Atypical_PIKK_ATM_ATM_ST	Q5TZA2	CROCC	Q13315	ATM	S471	S473C	473	Missense	proximal	2	no	9.820	8.567	EPSD	TCGA;ICGC;COSMIC	9.540	Loss
Atypical_PIKK_ATM_ATM_ST	Q5TZA2	CROCC	Q13315	ATM	S471	T476A	476	Missense	distal	5	no	9.820	9.885	EPSD	TCGA;ICGC;COSMIC	9.540	Up-regulation
Atypical_PIKK_ATM_ATM_ST	Q5TZA2	CROCC	Q13315	ATM	S471	V468A	468	Missense	distal	-3	no	9.820	8.957	EPSD	TCGA;ICGC;COSMIC	9.540	Loss
Atypical_PIKK_ATM_ATM_ST	Q5TZA2	CROCC	Q13315	ATM	S494	P495L	495	Missense	proximal	1	no	10.426	8.871	EPSD	TCGA;ICGC;COSMIC	9.540	Loss
Atypical_PIKK_ATM_ATM_ST	Q5TZA2	CROCC	Q13315	ATM	S494	G489D	489	Missense	distal	-5	no	10.426	10.160	EPSD	TCGA;ICGC;COSMIC	9.540	Down-regulation
Atypical_PIKK_ATM_ATM_ST	Q5TZA2	CROCC	Q13315	ATM	S506	S512F	512	Missense	distal	6	no	10.429	10.353	EPSD	TCGA;ICGC	9.540	Down-regulation
Atypical_PIKK_ATM_ATM_ST	Q5TZA2	CROCC	Q13315	ATM	S506	R508H	508	Missense	proximal	2	no	10.429	10.745	EPSD	TCGA;ICGC;COSMIC	9.540	Up-regulation
Atypical_PIKK_ATM_ATM_ST	Q5TZA2	CROCC	Q13315	ATM	S506	R505C	505	Missense	proximal	-1	no	10.429	10.604	EPSD	TCGA;ICGC	9.540	Up-regulation
Atypical_PIKK_ATM_ATM_ST	Q5TZA2	CROCC	Q13315	ATM	S512	S512F	512	Missense	central	0	yes	10.006	0.000	EPSD	TCGA;ICGC	9.540	Loss
Atypical_PIKK_ATM_ATM_ST	Q5TZA2	CROCC	Q13315	ATM	S512	R508H	508	Missense	distal	-4	no	10.006	10.136	EPSD	TCGA;ICGC;COSMIC	9.540	Up-regulation
Atypical_PIKK_ATM_ATM_ST	Q5TZA2	CROCC	Q13315	ATM	S512	R505C	505	Missense	distal	-7	no	10.006	9.731	EPSD	TCGA;ICGC	9.540	Down-regulation
Atypical_PIKK_ATM_ATM_ST	Q5TZA2	CROCC	Q13315	ATM	S737	A743T	743	Missense	distal	6	no	11.065	11.049	EPSD	TCGA;ICGC;COSMIC	9.540	Down-regulation
Atypical_PIKK_ATM_ATM_ST	Q5TZA2	CROCC	Q13315	ATM	S737	L741R	741	Missense	distal	4	no	11.065	10.905	EPSD	TCGA;ICGC;COSMIC	9.540	Down-regulation
Atypical_PIKK_ATM_ATM_ST	Q5TZA2	CROCC	Q13315	ATM	S830	R826C	826	Missense	distal	-4	no	13.449	12.686	EPSD	TCGA;ICGC;COSMIC;CCLE	9.540	Down-regulation
Atypical_PIKK_ATM_ATM_ST	Q5TZA2	CROCC	Q13315	ATM	T958	R952Q	952	Missense	distal	-6	no	13.100	13.243	EPSD	TCGA;ICGC;COSMIC	9.540	Up-regulation
Atypical_PIKK_ATM_ATM_ST	Q5TZA2	CROCC	Q13315	ATM	S1486	P1493L	1493	Missense	distal	7	no	13.105	13.106	EPSD	TCGA;ICGC;COSMIC	9.540	Up-regulation
Atypical_PIKK_ATM_ATM_ST	Q5TZA2	CROCC	Q13315	ATM	S1499	P1493L	1493	Missense	distal	-6	no	10.289	10.060	EPSD	TCGA;ICGC;COSMIC	9.540	Down-regulation
Atypical_PIKK_ATM_ATM_ST	Q5TZA2	CROCC	Q13315	ATM	S1499	L1502P	1502	Missense	distal	3	no	10.289	10.159	EPSD	TCGA;ICGC;COSMIC	9.540	Down-regulation
Atypical_PIKK_ATM_ATM_ST	Q5TZA2	CROCC	Q13315	ATM	S1499	P1504L	1504	Missense	distal	5	no	10.289	10.272	EPSD	TCGA;ICGC;COSMIC;GDSC	9.540	Down-regulation
Atypical_PIKK_ATM_ATM_ST	Q5TZA2	CROCC	Q13315	ATM	S1608	S1608N	1608	Missense	central	0	yes	10.370	0.000	EPSD	TCGA;ICGC;COSMIC	9.540	Loss
Atypical_PIKK_ATM_ATM_ST	Q5TZA2	CROCC	Q13315	ATM	S2009	S2012F	2012	Missense	distal	3	no	9.589	10.171	EPSD	TCGA;ICGC	9.540	Up-regulation
Atypical_PIKK_ATM_ATM_ST	Q5TZA2	CROCC	Q13315	ATM	S2009	E2016D	2016	Missense	distal	7	no	9.589	9.602	EPSD	TCGA;ICGC	9.540	Up-regulation
Atypical_PIKK_ATM_ATM_ST	Q96J02	ITCH	Q13315	ATM	S6	Q7R	7	Missense	proximal	1	no	12.929	6.278	EPSD	TCGA;ICGC;COSMIC	9.540	Loss
Atypical_PIKK_ATM_ATM_ST	Q96J02	ITCH	Q13315	ATM	S18	Q21E	21	Missense	distal	3	no	14.695	14.436	EPSD	TCGA;ICGC;COSMIC	9.540	Down-regulation
Atypical_PIKK_ATM_ATM_ST	Q96J02	ITCH	Q13315	ATM	S62	T60S	60	Missense	proximal	-2	no	11.024	11.112	EPSD	TCGA;ICGC;COSMIC	9.540	Up-regulation
Atypical_PIKK_ATM_ATM_ST	Q96J02	ITCH	Q13315	ATM	S221	E225K	225	Missense	distal	4	no	11.165	11.542	EPSD	TCGA;ICGC;COSMIC	9.540	Up-regulation
Atypical_PIKK_ATM_ATM_ST	Q96J02	ITCH	Q13315	ATM	S221	G220E	220	Missense	proximal	-1	no	11.165	11.566	EPSD	TCGA;ICGC;COSMIC	9.540	Up-regulation
Atypical_PIKK_ATM_ATM_ST	Q96J02	ITCH	Q13315	ATM	S221	D226Y	226	Missense	distal	5	no	11.165	11.143	EPSD	TCGA;ICGC;COSMIC	9.540	Down-regulation
Atypical_PIKK_ATM_ATM_ST	Q96J02	ITCH	Q13315	ATM	S221	N219Y	219	Missense	proximal	-2	no	11.165	11.175	EPSD	TCGA;ICGC;COSMIC	9.540	Up-regulation
Atypical_PIKK_ATM_ATM_ST	Q96J02	ITCH	Q13315	ATM	S240	S240C	240	Missense	central	0	yes	9.932	0.000	EPSD	TCGA;ICGC;COSMIC	9.540	Loss
Atypical_PIKK_ATM_ATM_ST	Q96J02	ITCH	Q13315	ATM	S687	I680V	680	Missense	distal	-7	no	10.240	10.424	EPSD	TCGA;ICGC;COSMIC	9.540	Up-regulation
Atypical_PIKK_ATM_ATM_ST	Q9BXW9	FANCD2	Q13315	ATM	S167	F161V	161	Missense	distal	-6	no	10.834	11.108	EPSD	TCGA;ICGC;COSMIC	9.540	Up-regulation
Atypical_PIKK_ATM_ATM_ST	Q9BXW9	FANCD2	Q13315	ATM	S167	R174Q	174	Missense	distal	7	no	10.834	10.809	EPSD	TCGA;ICGC;COSMIC	9.540	Down-regulation
Atypical_PIKK_ATM_ATM_ST	Q9BXW9	FANCD2	Q13315	ATM	S178	R174Q	174	Missense	distal	-4	no	10.508	10.874	EPSD	TCGA;ICGC;COSMIC	9.540	Up-regulation
Atypical_PIKK_ATM_ATM_ST	Q9BXW9	FANCD2	Q13315	ATM	S178	R185T	185	Missense	distal	7	no	10.508	10.490	EPSD	TCGA;ICGC;COSMIC	9.540	Down-regulation
Atypical_PIKK_ATM_ATM_ST	Q9BXW9	FANCD2	Q13315	ATM	S222	E217K	217	Missense	distal	-5	no	13.575	13.657	PhosphoSitePlus;EPSD	TCGA;ICGC;COSMIC	9.540	Up-regulation
Atypical_PIKK_ATM_ATM_ST	Q9BXW9	FANCD2	Q13315	ATM	S251	R253Q	253	Missense	proximal	2	no	9.334	10.029	EPSD	TCGA;ICGC	9.540	Gain
Atypical_PIKK_ATM_ATM_ST	Q9BXW9	FANCD2	Q13315	ATM	S319	L312W	312	Missense	distal	-7	no	12.400	12.399	EPSD	TCGA;ICGC;COSMIC	9.540	Down-regulation
Atypical_PIKK_ATM_ATM_ST	Q9BXW9	FANCD2	Q13315	ATM	S338	N334H	334	Missense	distal	-4	no	9.603	9.851	EPSD	TCGA;ICGC;COSMIC	9.540	Up-regulation
Atypical_PIKK_ATM_ATM_ST	Q9BXW9	FANCD2	Q13315	ATM	S592	A587T	587	Missense	distal	-5	no	10.502	10.421	EPSD	TCGA;ICGC;COSMIC	9.540	Down-regulation
Atypical_PIKK_ATM_ATM_ST	Q9BXW9	FANCD2	Q13315	ATM	T596	A600G	600	Missense	distal	4	no	13.484	13.960	EPSD	TCGA;ICGC;COSMIC	9.540	Up-regulation
Atypical_PIKK_ATM_ATM_ST	Q9BXW9	FANCD2	Q13315	ATM	T608	Q609H	609	Missense	proximal	1	no	12.982	-1.927	EPSD	TCGA;ICGC;COSMIC	9.540	Loss
Atypical_PIKK_ATM_ATM_ST	Q9BXW9	FANCD2	Q13315	ATM	T691	G685A	685	Missense	distal	-6	no	14.390	14.571	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	9.540	Up-regulation
Atypical_PIKK_ATM_ATM_ST	Q9BXW9	FANCD2	Q13315	ATM	T691	E687K	687	Missense	distal	-4	no	14.390	13.418	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	9.540	Down-regulation
Atypical_PIKK_ATM_ATM_ST	Q9BXW9	FANCD2	Q13315	ATM	S717	V715A	715	Missense	proximal	-2	no	14.837	15.314	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	9.540	Up-regulation
Atypical_PIKK_ATM_ATM_ST	Q9BXW9	FANCD2	Q13315	ATM	S784	S780L	780	Missense	distal	-4	no	10.251	9.312	EPSD	TCGA;ICGC;COSMIC	9.540	Loss
Atypical_PIKK_ATM_ATM_ST	Q9BXW9	FANCD2	Q13315	ATM	S882	S886L	886	Missense	distal	4	no	10.665	11.007	EPSD	TCGA;ICGC;COSMIC	9.540	Up-regulation
Atypical_PIKK_ATM_ATM_ST	Q9BXW9	FANCD2	Q13315	ATM	S882	E888D	888	Missense	distal	6	no	10.665	10.619	EPSD	TCGA;ICGC;COSMIC	9.540	Down-regulation
Atypical_PIKK_ATM_ATM_ST	Q9BXW9	FANCD2	Q13315	ATM	S886	S886L	886	Missense	central	0	yes	10.619	0.000	EPSD	TCGA;ICGC;COSMIC	9.540	Loss
Atypical_PIKK_ATM_ATM_ST	Q9BXW9	FANCD2	Q13315	ATM	S886	E888D	888	Missense	proximal	2	no	10.619	10.489	EPSD	TCGA;ICGC;COSMIC	9.540	Down-regulation
Atypical_PIKK_ATM_ATM_ST	Q9BXW9	FANCD2	Q13315	ATM	S1257	E1262D	1262	Missense	distal	5	no	16.719	16.976	EPSD	TCGA;ICGC;COSMIC	9.540	Up-regulation
Atypical_PIKK_ATM_ATM_ST	Q9BXW9	FANCD2	Q13315	ATM	S1257	S1257W	1257	Missense	central	0	yes	16.719	0.000	EPSD	TCGA;ICGC;COSMIC	9.540	Loss
Atypical_PIKK_ATM_ATM_ST	Q9BXW9	FANCD2	Q13315	ATM	S1257	S1257L	1257	Missense	central	0	yes	16.719	0.000	EPSD	TCGA;ICGC;COSMIC	9.540	Loss
Atypical_PIKK_ATM_ATM_ST	Q9BXW9	FANCD2	Q13315	ATM	S1401	S1404F	1404	Missense	distal	3	no	13.353	13.935	EPSD	TCGA;ICGC;COSMIC	9.540	Up-regulation
Atypical_PIKK_ATM_ATM_ST	Q9BXW9	FANCD2	Q13315	ATM	S1404	S1404F	1404	Missense	central	0	yes	16.008	0.000	EPSD	TCGA;ICGC;COSMIC	9.540	Loss
Atypical_PIKK_ATM_ATM_ST	Q9BXW9	FANCD2	Q13315	ATM	S1443	G1437C	1437	Missense	distal	-6	no	10.763	10.584	EPSD	TCGA;ICGC;COSMIC	9.540	Down-regulation
Atypical_PIKK_ATM_ATM_ST	Q969H0	FBXW7	Q13315	ATM	S26	M33I	33	Missense	distal	7	no	15.064	15.061	PhosphoSitePlus	TCGA;ICGC;COSMIC	9.540	Down-regulation
Atypical_PIKK_ATM_ATM_ST	Q969H0	FBXW7	Q13315	ATM	S176	E177Q	177	Missense	proximal	1	no	6.346	12.243	EPSD	TCGA;ICGC;COSMIC	9.540	Gain
Atypical_PIKK_ATM_ATM_ST	Q969H0	FBXW7	Q13315	ATM	S372	G368E	368	Missense	distal	-4	no	8.705	9.772	EPSD	TCGA;ICGC;COSMIC	9.540	Gain
Atypical_PIKK_ATM_ATM_ST	Q969H0	FBXW7	Q13315	ATM	S688	R689Q	689	Missense	proximal	1	no	5.575	12.227	EPSD	TCGA;ICGC;COSMIC	9.540	Gain
Atypical_PIKK_ATM_ATM_ST	Q6PCD5	RFWD3	Q13315	ATM	S46	P50S	50	Missense	distal	4	no	14.627	14.504	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	9.540	Down-regulation
Atypical_PIKK_ATM_ATM_ST	Q6PCD5	RFWD3	Q13315	ATM	S63	A65V	65	Missense	proximal	2	no	15.780	15.471	PhosphoSitePlus;EPSD	TCGA;ICGC;COSMIC	9.540	Down-regulation
Atypical_PIKK_ATM_ATM_ST	Q6PCD5	RFWD3	Q13315	ATM	S63	E59K	59	Missense	distal	-4	no	15.780	14.808	PhosphoSitePlus;EPSD	TCGA;ICGC;COSMIC	9.540	Down-regulation
Atypical_PIKK_ATM_ATM_ST	Q6PCD5	RFWD3	Q13315	ATM	S63	P57S	57	Missense	distal	-6	no	15.780	15.839	PhosphoSitePlus;EPSD	TCGA;ICGC	9.540	Up-regulation
Atypical_PIKK_ATM_ATM_ST	Q6PCD5	RFWD3	Q13315	ATM	S353	A349D	349	Missense	distal	-4	no	9.112	9.618	EPSD	TCGA;ICGC;COSMIC	9.540	Gain
Atypical_PIKK_ATM_ATM_ST	Q6PCD5	RFWD3	Q13315	ATM	S408	Q407E	407	Missense	proximal	-1	no	12.778	13.055	EPSD	TCGA;ICGC;COSMIC	9.540	Up-regulation
Atypical_PIKK_ATM_ATM_ST	Q6PCD5	RFWD3	Q13315	ATM	S408	T404M	404	Missense	distal	-4	no	12.778	12.154	EPSD	TCGA;ICGC;COSMIC	9.540	Down-regulation
Atypical_PIKK_ATM_ATM_ST	Q6PCD5	RFWD3	Q13315	ATM	S408	S408G	408	Missense	central	0	yes	12.778	0.000	EPSD	TCGA	9.540	Loss
Atypical_PIKK_ATM_ATM_ST	Q6PCD5	RFWD3	Q13315	ATM	S417	C424F	424	Missense	distal	7	no	14.923	14.931	EPSD	TCGA;ICGC;COSMIC	9.540	Up-regulation
Atypical_PIKK_ATM_ATM_ST	Q6PCD5	RFWD3	Q13315	ATM	S428	C424F	424	Missense	distal	-4	no	10.097	10.271	EPSD	TCGA;ICGC;COSMIC	9.540	Up-regulation
Atypical_PIKK_ATM_ATM_ST	Q6PCD5	RFWD3	Q13315	ATM	S428	S427F	427	Missense	proximal	-1	no	10.097	9.671	EPSD	TCGA;ICGC;COSMIC	9.540	Down-regulation
Atypical_PIKK_ATM_ATM_ST	Q6PCD5	RFWD3	Q13315	ATM	S490	N486Y	486	Missense	distal	-4	no	15.096	14.923	EPSD	TCGA;ICGC;COSMIC	9.540	Down-regulation
Atypical_PIKK_ATM_ATM_ST	Q6PCD5	RFWD3	Q13315	ATM	S490	N486S	486	Missense	distal	-4	no	15.096	16.024	EPSD	TCGA;ICGC;COSMIC	9.540	Up-regulation
Atypical_PIKK_ATM_ATM_ST	Q6PCD5	RFWD3	Q13315	ATM	S490	P494S	494	Missense	distal	4	no	15.096	14.973	EPSD	TCGA;ICGC	9.540	Down-regulation
Atypical_PIKK_ATM_ATM_ST	Q6PCD5	RFWD3	Q13315	ATM	S490	P494L	494	Missense	distal	4	no	15.096	15.315	EPSD	TCGA;ICGC	9.540	Up-regulation
Atypical_PIKK_ATM_ATM_ST	Q9UQR1	ZNF148	Q13315	ATM	S23	S22C	22	Missense	proximal	-1	no	10.657	10.457	EPSD	TCGA;ICGC;COSMIC	9.540	Down-regulation
Atypical_PIKK_ATM_ATM_ST	Q9UQR1	ZNF148	Q13315	ATM	S23	S23P	23	Missense	central	0	yes	10.657	0.000	EPSD	TCGA;ICGC;COSMIC	9.540	Loss
Atypical_PIKK_ATM_ATM_ST	Q9UQR1	ZNF148	Q13315	ATM	S23	D18N	18	Missense	distal	-5	no	10.657	10.840	EPSD	TCGA;ICGC	9.540	Up-regulation
Atypical_PIKK_ATM_ATM_ST	Q9UQR1	ZNF148	Q13315	ATM	S202	R207C	207	Missense	distal	5	no	12.906	12.966	PhosphoSitePlus	TCGA;ICGC;COSMIC	9.540	Up-regulation
Atypical_PIKK_ATM_ATM_ST	Q9UQR1	ZNF148	Q13315	ATM	S250	H249D	249	Missense	proximal	-1	no	9.873	10.022	EPSD	TCGA;ICGC;COSMIC	9.540	Up-regulation
Atypical_PIKK_ATM_ATM_ST	Q9UQR1	ZNF148	Q13315	ATM	S250	R247I	247	Missense	distal	-3	no	9.873	9.802	EPSD	TCGA;ICGC;COSMIC;GDSC;CCLE	9.540	Down-regulation
Atypical_PIKK_ATM_ATM_ST	Q9UQR1	ZNF148	Q13315	ATM	T416	E419D	419	Missense	distal	3	no	9.378	9.737	EPSD	TCGA;ICGC;COSMIC	9.540	Gain
Atypical_PIKK_ATM_ATM_ST	Q9UQR1	ZNF148	Q13315	ATM	S625	L628R	628	Missense	distal	3	no	9.773	9.677	EPSD	TCGA;ICGC;COSMIC	9.540	Down-regulation
Atypical_PIKK_ATM_ATM_ST	Q9UQR1	ZNF148	Q13315	ATM	S625	D620Y	620	Missense	distal	-5	no	9.773	10.008	EPSD	TCGA;ICGC;COSMIC	9.540	Up-regulation
Atypical_PIKK_ATM_ATM_ST	Q9UQR1	ZNF148	Q13315	ATM	S665	S665Y	665	Missense	central	0	yes	9.667	0.000	EPSD	TCGA;ICGC;COSMIC	9.540	Loss
Atypical_PIKK_ATM_ATM_ST	Q9UQR1	ZNF148	Q13315	ATM	S665	P671L	671	Missense	distal	6	no	9.667	9.621	EPSD	TCGA;ICGC;COSMIC	9.540	Down-regulation
Atypical_PIKK_ATM_ATM_ST	Q9UQR1	ZNF148	Q13315	ATM	S683	S683L	683	Missense	central	0	yes	12.936	0.000	EPSD	TCGA;ICGC;COSMIC	9.540	Loss
Atypical_PIKK_ATM_ATM_ST	Q9UQR1	ZNF148	Q13315	ATM	S683	G677V	677	Missense	distal	-6	no	12.936	12.882	EPSD	TCGA;ICGC;COSMIC	9.540	Down-regulation
Atypical_PIKK_ATM_ATM_ST	Q9UQR1	ZNF148	Q13315	ATM	S683	P688L	688	Missense	distal	5	no	12.936	12.919	EPSD	TCGA;ICGC;COSMIC	9.540	Down-regulation
Atypical_PIKK_ATM_ATM_ST	Q9UQR1	ZNF148	Q13315	ATM	S763	S767L	767	Missense	distal	4	no	9.279	9.620	EPSD	TCGA;ICGC;COSMIC	9.540	Gain
Atypical_PIKK_ATM_ATM_ST	Q9UQR1	ZNF148	Q13315	ATM	S784	D786N	786	Missense	proximal	2	no	13.254	12.233	EPSD	TCGA;ICGC;COSMIC	9.540	Down-regulation
Atypical_PIKK_ATM_ATM_ST	Q9UQR1	ZNF148	Q13315	ATM	S784	S784L	784	Missense	central	0	yes	13.254	0.000	EPSD	TCGA;ICGC;COSMIC	9.540	Loss
Atypical_PIKK_ATM_ATM_ST	Q9UQR1	ZNF148	Q13315	ATM	S784	Q791H	791	Missense	distal	7	no	13.254	13.273	EPSD	TCGA;ICGC;COSMIC	9.540	Up-regulation
Atypical_PIKK_ATM_ATM_ST	Q9UQR1	ZNF148	Q13315	ATM	S784	R778I	778	Missense	distal	-6	no	13.254	13.034	EPSD	TCGA;ICGC	9.540	Down-regulation
Atypical_PIKK_ATM_ATM_ST	Q96RL1	UIMC1	Q13315	ATM	S140	Q144E	144	Missense	distal	4	no	16.313	15.982	EPSD	TCGA;ICGC;COSMIC	9.540	Down-regulation
Atypical_PIKK_ATM_ATM_ST	Q96RL1	UIMC1	Q13315	ATM	S140	S140F	140	Missense	central	0	yes	16.313	0.000	EPSD	TCGA;ICGC;COSMIC	9.540	Loss
Atypical_PIKK_ATM_ATM_ST	Q96RL1	UIMC1	Q13315	ATM	S140	G137E	137	Missense	distal	-3	no	16.313	15.876	EPSD	TCGA;ICGC;COSMIC	9.540	Down-regulation
Atypical_PIKK_ATM_ATM_ST	Q96RL1	UIMC1	Q13315	ATM	S171	I170M	170	Missense	proximal	-1	no	10.004	9.933	EPSD	TCGA;ICGC;COSMIC	9.540	Down-regulation
Atypical_PIKK_ATM_ATM_ST	Q96RL1	UIMC1	Q13315	ATM	S171	N174I	174	Missense	distal	3	no	10.004	10.305	EPSD	TCGA;ICGC;COSMIC	9.540	Up-regulation
Atypical_PIKK_ATM_ATM_ST	Q96RL1	UIMC1	Q13315	ATM	S250	V247F	247	Missense	distal	-3	no	9.102	9.756	EPSD	TCGA;ICGC;COSMIC	9.540	Gain
Atypical_PIKK_ATM_ATM_ST	Q96RL1	UIMC1	Q13315	ATM	S402	E408Q	408	Missense	distal	6	no	15.510	15.463	EPSD	TCGA;ICGC;COSMIC	9.540	Down-regulation
Atypical_PIKK_ATM_ATM_ST	Q96RL1	UIMC1	Q13315	ATM	S402	S402F	402	Missense	central	0	yes	15.510	0.000	EPSD	TCGA;ICGC;COSMIC	9.540	Loss
Atypical_PIKK_ATM_ATM_ST	Q96RL1	UIMC1	Q13315	ATM	T448	S452C	452	Missense	distal	4	no	11.381	11.891	EPSD	TCGA;ICGC;COSMIC	9.540	Up-regulation
Atypical_PIKK_ATM_ATM_ST	Q96RL1	UIMC1	Q13315	ATM	S453	S452C	452	Missense	proximal	-1	no	10.311	10.111	EPSD	TCGA;ICGC;COSMIC	9.540	Down-regulation
Atypical_PIKK_ATM_ATM_ST	Q96RL1	UIMC1	Q13315	ATM	S463	P464L	464	Missense	proximal	1	no	10.005	8.450	EPSD	TCGA;ICGC;COSMIC	9.540	Loss
Atypical_PIKK_ATM_ATM_ST	Q96RL1	UIMC1	Q13315	ATM	S644	I641M	641	Missense	distal	-3	no	10.025	9.710	EPSD	TCGA;COSMIC	9.540	Down-regulation
Atypical_PIKK_ATM_ATM_ST	Q96RL1	UIMC1	Q13315	ATM	S644	D638N	638	Missense	distal	-6	no	10.025	9.936	EPSD	TCGA;COSMIC	9.540	Down-regulation
Atypical_PIKK_ATM_ATM_ST	Q96RL1	UIMC1	Q13315	ATM	S644	S637L	637	Missense	distal	-7	no	10.025	9.437	EPSD	TCGA;COSMIC	9.540	Loss
Atypical_PIKK_ATM_ATM_ST	Q96RL1	UIMC1	Q13315	ATM	S644	A648S	648	Missense	distal	4	no	10.025	10.372	EPSD	TCGA;COSMIC	9.540	Up-regulation
Atypical_PIKK_ATM_ATM_ST	Q96T60	PNKP	Q13315	ATM	S14	L10S	10	Missense	distal	-4	no	9.314	10.253	EPSD	TCGA;ICGC;COSMIC	9.540	Gain
Atypical_PIKK_ATM_ATM_ST	Q96T60	PNKP	Q13315	ATM	S114	P119L	119	Missense	distal	5	no	15.948	15.930	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC;CCLE	9.540	Down-regulation
Atypical_PIKK_ATM_ATM_ST	Q96T60	PNKP	Q13315	ATM	S126	L124V	124	Missense	proximal	-2	no	14.074	13.799	PhosphoSitePlus;EPSD	TCGA;ICGC;COSMIC	9.540	Down-regulation
Atypical_PIKK_ATM_ATM_ST	Q96T60	PNKP	Q13315	ATM	S126	S126F	126	Missense	central	0	yes	14.074	0.000	PhosphoSitePlus;EPSD	TCGA;ICGC	9.540	Loss
Atypical_PIKK_ATM_ATM_ST	Q96T60	PNKP	Q13315	ATM	S126	A133T	133	Missense	distal	7	no	14.074	14.060	PhosphoSitePlus;EPSD	TCGA;ICGC;COSMIC	9.540	Down-regulation
Atypical_PIKK_ATM_ATM_ST	Q96T60	PNKP	Q13315	ATM	S126	P119L	119	Missense	distal	-7	no	14.074	13.723	PhosphoSitePlus;EPSD	TCGA;ICGC;COSMIC;CCLE	9.540	Down-regulation
Atypical_PIKK_ATM_ATM_ST	Q96T60	PNKP	Q13315	ATM	S364	A359V	359	Missense	distal	-5	no	10.302	10.423	EPSD	TCGA	9.540	Up-regulation
Atypical_PIKK_ATM_ATM_ST	O75943	RAD17	Q13315	ATM	S81	E87K	87	Missense	distal	6	no	11.061	11.015	EPSD	TCGA;COSMIC	9.540	Down-regulation
Atypical_PIKK_ATM_ATM_ST	O75943	RAD17	Q13315	ATM	S81	E79Q	79	Missense	proximal	-2	no	11.061	10.756	EPSD	TCGA;COSMIC	9.540	Down-regulation
Atypical_PIKK_ATM_ATM_ST	O75943	RAD17	Q13315	ATM	S81	S81L	81	Missense	central	0	yes	11.061	0.000	EPSD	TCGA;COSMIC	9.540	Loss
Atypical_PIKK_ATM_ATM_ST	O75943	RAD17	Q13315	ATM	S646	L643I	643	Missense	distal	-3	no	15.374	15.835	EPSD;PhosphoSitePlus	TCGA;COSMIC	9.540	Up-regulation
Atypical_PIKK_ATM_ATM_ST	O75943	RAD17	Q13315	ATM	S646	P644S	644	Missense	proximal	-2	no	15.374	15.611	EPSD;PhosphoSitePlus	TCGA;COSMIC	9.540	Up-regulation
Atypical_PIKK_ATM_ATM_ST	O75943	RAD17	Q13315	ATM	S646	S642F	642	Missense	distal	-4	no	15.374	13.975	EPSD;PhosphoSitePlus	TCGA	9.540	Down-regulation
Atypical_PIKK_ATM_ATM_ST	O75943	RAD17	Q13315	ATM	S656	F661C	661	Missense	distal	5	no	16.725	16.645	EPSD;PhosphoSitePlus	TCGA	9.540	Down-regulation
Atypical_PIKK_ATM_ATM_ST	Q01094	E2F1	Q13315	ATM	S131	E124Q	124	Missense	distal	-7	no	9.642	9.087	EPSD	TCGA;ICGC;COSMIC	9.540	Loss
Atypical_PIKK_ATM_ATM_ST	Q01094	E2F1	Q13315	ATM	S131	R127H	127	Missense	distal	-4	no	9.642	9.773	EPSD	TCGA;ICGC;COSMIC;GDSC;CCLE	9.540	Up-regulation
Atypical_PIKK_ATM_ATM_ST	Q01094	E2F1	Q13315	ATM	S131	R138C	138	Missense	distal	7	no	9.642	9.660	EPSD	TCGA;ICGC;COSMIC;GDSC;CCLE	9.540	Up-regulation
Atypical_PIKK_ATM_ATM_ST	Q01094	E2F1	Q13315	ATM	S307	I306V	306	Missense	proximal	-1	no	9.855	9.652	EPSD	TCGA;ICGC;COSMIC	9.540	Down-regulation
Atypical_PIKK_ATM_ATM_ST	Q01094	E2F1	Q13315	ATM	S313	I306V	306	Missense	distal	-7	no	13.870	14.053	EPSD	TCGA;ICGC;COSMIC	9.540	Up-regulation
Atypical_PIKK_ATM_ATM_ST	Q01094	E2F1	Q13315	ATM	S318	E321D	321	Missense	distal	3	no	9.741	10.100	EPSD	TCGA;ICGC;COSMIC	9.540	Up-regulation
Atypical_PIKK_ATM_ATM_ST	Q01094	E2F1	Q13315	ATM	S347	P346L	346	Missense	proximal	-1	no	14.776	14.933	EPSD	TCGA;ICGC;COSMIC	9.540	Up-regulation
Atypical_PIKK_ATM_ATM_ST	Q00987	MDM2	Q13315	ATM	S17	T16A	16	Missense	proximal	-1	no	15.241	15.070	EPSD	TCGA;COSMIC	9.540	Down-regulation
Atypical_PIKK_ATM_ATM_ST	O96017	CHEK2	Q13315	ATM	S19	S24C	24	Missense	distal	5	no	16.504	16.730	EPSD	TCGA;ICGC;COSMIC	9.540	Up-regulation
Atypical_PIKK_ATM_ATM_ST	O96017	CHEK2	Q13315	ATM	S19	C18S	18	Missense	proximal	-1	no	16.504	16.704	EPSD	TCGA;ICGC;COSMIC	9.540	Up-regulation
Atypical_PIKK_ATM_ATM_ST	O96017	CHEK2	Q13315	ATM	S19	S16R	16	Missense	distal	-3	no	16.504	17.244	EPSD	TCGA;ICGC;COSMIC	9.540	Up-regulation
Atypical_PIKK_ATM_ATM_ST	O96017	CHEK2	Q13315	ATM	T26	S24C	24	Missense	proximal	-2	no	14.091	13.629	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	9.540	Down-regulation
Atypical_PIKK_ATM_ATM_ST	O96017	CHEK2	Q13315	ATM	S28	S24C	24	Missense	distal	-4	no	14.052	12.479	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	9.540	Down-regulation
Atypical_PIKK_ATM_ATM_ST	O96017	CHEK2	Q13315	ATM	S35	S42C	42	Missense	distal	7	no	13.848	13.900	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	9.540	Up-regulation
Atypical_PIKK_ATM_ATM_ST	O96017	CHEK2	Q13315	ATM	S50	S53F	53	Missense	distal	3	no	15.257	15.839	EPSD	TCGA;ICGC;COSMIC	9.540	Up-regulation
Atypical_PIKK_ATM_ATM_ST	O96017	CHEK2	Q13315	ATM	S50	S56R	56	Missense	distal	6	no	15.257	15.239	EPSD	TCGA;ICGC;COSMIC	9.540	Down-regulation
Atypical_PIKK_ATM_ATM_ST	O96017	CHEK2	Q13315	ATM	T68	E70G	70	Missense	proximal	2	no	14.453	13.083	EPSD;PhosphoSitePlus	TCGA	9.540	Down-regulation
Atypical_PIKK_ATM_ATM_ST	O96017	CHEK2	Q13315	ATM	S357	E351Q	351	Missense	distal	-6	no	14.674	14.450	EPSD	TCGA;COSMIC	9.540	Down-regulation
Atypical_PIKK_ATM_ATM_ST	Q8IY92	SLX4	Q13315	ATM	S115	K121R	121	Missense	distal	6	no	13.628	13.631	EPSD	TCGA;ICGC;COSMIC	9.540	Up-regulation
Atypical_PIKK_ATM_ATM_ST	Q8IY92	SLX4	Q13315	ATM	S115	P112L	112	Missense	distal	-3	no	13.628	13.640	EPSD	TCGA;ICGC;COSMIC	9.540	Up-regulation
Atypical_PIKK_ATM_ATM_ST	Q8IY92	SLX4	Q13315	ATM	S169	S173C	173	Missense	distal	4	no	9.233	9.743	EPSD	TCGA;ICGC;COSMIC	9.540	Gain
Atypical_PIKK_ATM_ATM_ST	Q8IY92	SLX4	Q13315	ATM	S173	S173C	173	Missense	central	0	yes	9.696	0.000	EPSD	TCGA;ICGC;COSMIC	9.540	Loss
Atypical_PIKK_ATM_ATM_ST	Q8IY92	SLX4	Q13315	ATM	S173	R174G	174	Missense	proximal	1	no	9.696	9.874	EPSD	TCGA;ICGC;COSMIC	9.540	Up-regulation
Atypical_PIKK_ATM_ATM_ST	Q8IY92	SLX4	Q13315	ATM	S173	L172F	172	Missense	proximal	-1	no	9.696	9.405	EPSD	TCGA;ICGC;COSMIC	9.540	Loss
Atypical_PIKK_ATM_ATM_ST	Q8IY92	SLX4	Q13315	ATM	T177	L172F	172	Missense	distal	-5	no	9.491	9.792	EPSD	TCGA;ICGC;COSMIC	9.540	Gain
Atypical_PIKK_ATM_ATM_ST	Q8IY92	SLX4	Q13315	ATM	S186	L193F	193	Missense	distal	7	no	14.902	14.943	EPSD	TCGA;ICGC;COSMIC	9.540	Up-regulation
Atypical_PIKK_ATM_ATM_ST	Q8IY92	SLX4	Q13315	ATM	S186	D185A	185	Missense	proximal	-1	no	14.902	14.796	EPSD	TCGA;ICGC;COSMIC	9.540	Down-regulation
Atypical_PIKK_ATM_ATM_ST	Q8IY92	SLX4	Q13315	ATM	S228	E230K	230	Missense	proximal	2	no	9.626	8.295	EPSD	TCGA;ICGC;COSMIC	9.540	Loss
Atypical_PIKK_ATM_ATM_ST	Q8IY92	SLX4	Q13315	ATM	S228	E222K	222	Missense	distal	-6	no	9.626	9.325	EPSD	TCGA;ICGC;COSMIC	9.540	Loss
Atypical_PIKK_ATM_ATM_ST	Q8IY92	SLX4	Q13315	ATM	S228	L224F	224	Missense	distal	-4	no	9.626	9.166	EPSD	TCGA;ICGC;COSMIC	9.540	Loss
Atypical_PIKK_ATM_ATM_ST	Q8IY92	SLX4	Q13315	ATM	S228	A227T	227	Missense	proximal	-1	no	9.626	9.796	EPSD	TCGA;ICGC;COSMIC	9.540	Up-regulation
Atypical_PIKK_ATM_ATM_ST	Q8IY92	SLX4	Q13315	ATM	S228	L224S	224	Missense	distal	-4	no	9.626	10.565	EPSD	TCGA;ICGC;COSMIC	9.540	Up-regulation
Atypical_PIKK_ATM_ATM_ST	Q8IY92	SLX4	Q13315	ATM	S228	R223H	223	Missense	distal	-5	no	9.626	9.598	EPSD	TCGA;ICGC	9.540	Down-regulation
Atypical_PIKK_ATM_ATM_ST	Q8IY92	SLX4	Q13315	ATM	S383	S381G	381	Missense	proximal	-2	no	12.279	11.836	EPSD	TCGA;ICGC;COSMIC	9.540	Down-regulation
Atypical_PIKK_ATM_ATM_ST	Q8IY92	SLX4	Q13315	ATM	S467	R460C	460	Missense	distal	-7	no	11.693	11.418	EPSD	TCGA;ICGC;COSMIC;GDSC;CCLE	9.540	Down-regulation
Atypical_PIKK_ATM_ATM_ST	Q8IY92	SLX4	Q13315	ATM	S476	R481Q	481	Missense	distal	5	no	10.448	10.336	EPSD	TCGA;ICGC;COSMIC	9.540	Down-regulation
Atypical_PIKK_ATM_ATM_ST	Q8IY92	SLX4	Q13315	ATM	T500	A505V	505	Missense	distal	5	no	11.655	11.819	EPSD	TCGA;ICGC;COSMIC;GDSC;CCLE	9.540	Up-regulation
Atypical_PIKK_ATM_ATM_ST	Q8IY92	SLX4	Q13315	ATM	S584	R582Q	582	Missense	proximal	-2	no	9.829	10.147	EPSD	TCGA;ICGC;COSMIC	9.540	Up-regulation
Atypical_PIKK_ATM_ATM_ST	Q8IY92	SLX4	Q13315	ATM	S601	G594D	594	Missense	distal	-7	no	11.383	11.673	EPSD	TCGA;ICGC	9.540	Up-regulation
Atypical_PIKK_ATM_ATM_ST	Q8IY92	SLX4	Q13315	ATM	S659	S659L	659	Missense	central	0	yes	14.326	0.000	EPSD	TCGA;ICGC;COSMIC	9.540	Loss
Atypical_PIKK_ATM_ATM_ST	Q8IY92	SLX4	Q13315	ATM	S884	P885Q	885	Missense	proximal	1	no	11.524	16.325	EPSD	TCGA;ICGC;COSMIC	9.540	Up-regulation
Atypical_PIKK_ATM_ATM_ST	Q8IY92	SLX4	Q13315	ATM	S884	W879C	879	Missense	distal	-5	no	11.524	11.375	EPSD	TCGA;ICGC	9.540	Down-regulation
Atypical_PIKK_ATM_ATM_ST	Q8IY92	SLX4	Q13315	ATM	S884	A877D	877	Missense	distal	-7	no	11.524	11.398	EPSD	TCGA;ICGC	9.540	Down-regulation
Atypical_PIKK_ATM_ATM_ST	Q8IY92	SLX4	Q13315	ATM	S960	S960G	960	Missense	central	0	yes	10.071	0.000	EPSD	TCGA;ICGC;COSMIC	9.540	Loss
Atypical_PIKK_ATM_ATM_ST	Q8IY92	SLX4	Q13315	ATM	S1044	P1040S	1040	Missense	distal	-4	no	8.902	9.571	EPSD	TCGA;ICGC;COSMIC	9.540	Gain
Atypical_PIKK_ATM_ATM_ST	Q8IY92	SLX4	Q13315	ATM	S1066	R1062C	1062	Missense	distal	-4	no	12.570	11.807	EPSD	TCGA;ICGC;COSMIC	9.540	Down-regulation
Atypical_PIKK_ATM_ATM_ST	Q8IY92	SLX4	Q13315	ATM	S1066	G1063D	1063	Missense	distal	-3	no	12.570	12.537	EPSD	TCGA;ICGC;COSMIC	9.540	Down-regulation
Atypical_PIKK_ATM_ATM_ST	Q8IY92	SLX4	Q13315	ATM	S1070	G1063D	1063	Missense	distal	-7	no	9.715	10.005	EPSD	TCGA;ICGC;COSMIC	9.540	Up-regulation
Atypical_PIKK_ATM_ATM_ST	Q8IY92	SLX4	Q13315	ATM	S1121	K1120Q	1120	Missense	proximal	-1	no	9.742	9.868	EPSD	TCGA;ICGC;COSMIC	9.540	Up-regulation
Atypical_PIKK_ATM_ATM_ST	Q8IY92	SLX4	Q13315	ATM	T1127	K1120Q	1120	Missense	distal	-7	no	13.533	13.647	EPSD	TCGA;ICGC;COSMIC	9.540	Up-regulation
Atypical_PIKK_ATM_ATM_ST	Q8IY92	SLX4	Q13315	ATM	T1127	S1134L	1134	Missense	distal	7	no	13.533	13.552	EPSD	TCGA;ICGC;COSMIC	9.540	Up-regulation
Atypical_PIKK_ATM_ATM_ST	Q8IY92	SLX4	Q13315	ATM	S1136	S1143F	1143	Missense	distal	7	no	11.058	11.118	EPSD	TCGA;ICGC;COSMIC	9.540	Up-regulation
Atypical_PIKK_ATM_ATM_ST	Q8IY92	SLX4	Q13315	ATM	S1136	S1134L	1134	Missense	proximal	-2	no	11.058	10.669	EPSD	TCGA;ICGC;COSMIC	9.540	Down-regulation
Atypical_PIKK_ATM_ATM_ST	Q8IY92	SLX4	Q13315	ATM	S1136	R1137I	1137	Missense	proximal	1	no	11.058	0.984	EPSD	TCGA;ICGC	9.540	Loss
Atypical_PIKK_ATM_ATM_ST	Q8IY92	SLX4	Q13315	ATM	S1138	S1143F	1143	Missense	distal	5	no	14.212	14.518	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	9.540	Up-regulation
Atypical_PIKK_ATM_ATM_ST	Q8IY92	SLX4	Q13315	ATM	S1138	S1134L	1134	Missense	distal	-4	no	14.212	13.273	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	9.540	Down-regulation
Atypical_PIKK_ATM_ATM_ST	Q8IY92	SLX4	Q13315	ATM	S1138	R1137I	1137	Missense	proximal	-1	no	14.212	14.366	EPSD;PhosphoSitePlus	TCGA;ICGC	9.540	Up-regulation
Atypical_PIKK_ATM_ATM_ST	Q8IY92	SLX4	Q13315	ATM	S1185	R1187M	1187	Missense	proximal	2	no	11.136	11.077	EPSD	TCGA;ICGC;COSMIC	9.540	Down-regulation
Atypical_PIKK_ATM_ATM_ST	Q8IY92	SLX4	Q13315	ATM	S1204	Q1201E	1201	Missense	distal	-3	no	16.055	15.930	EPSD	TCGA;ICGC;COSMIC	9.540	Down-regulation
Atypical_PIKK_ATM_ATM_ST	Q8IY92	SLX4	Q13315	ATM	S1204	R1209G	1209	Missense	distal	5	no	16.055	16.068	EPSD	TCGA;ICGC;COSMIC	9.540	Up-regulation
Atypical_PIKK_ATM_ATM_ST	Q8IY92	SLX4	Q13315	ATM	S1206	Q1201E	1201	Missense	distal	-5	no	10.248	10.216	EPSD	TCGA;ICGC;COSMIC	9.540	Down-regulation
Atypical_PIKK_ATM_ATM_ST	Q8IY92	SLX4	Q13315	ATM	S1206	R1209G	1209	Missense	distal	3	no	10.248	10.193	EPSD	TCGA;ICGC;COSMIC	9.540	Down-regulation
Atypical_PIKK_ATM_ATM_ST	Q8IY92	SLX4	Q13315	ATM	S1206	V1213L	1213	Missense	distal	7	no	10.248	10.219	EPSD	TCGA;ICGC;COSMIC	9.540	Down-regulation
Atypical_PIKK_ATM_ATM_ST	Q8IY92	SLX4	Q13315	ATM	S1244	R1241C	1241	Missense	distal	-3	no	9.560	8.987	EPSD	TCGA;ICGC;COSMIC	9.540	Loss
Atypical_PIKK_ATM_ATM_ST	Q8IY92	SLX4	Q13315	ATM	S1244	E1247K	1247	Missense	distal	3	no	9.560	9.849	EPSD	TCGA;ICGC;COSMIC	9.540	Up-regulation
Atypical_PIKK_ATM_ATM_ST	Q8IY92	SLX4	Q13315	ATM	S1271	S1266N	1266	Missense	distal	-5	no	14.329	14.301	EPSD;PhosphoSitePlus	TCGA;ICGC	9.540	Down-regulation
Atypical_PIKK_ATM_ATM_ST	Q8IY92	SLX4	Q13315	ATM	T1273	S1266N	1266	Missense	distal	-7	no	10.277	10.090	EPSD	TCGA;ICGC	9.540	Down-regulation
Atypical_PIKK_ATM_ATM_ST	Q8IY92	SLX4	Q13315	ATM	T1288	V1284M	1284	Missense	distal	-4	no	12.351	12.333	EPSD	TCGA;ICGC;COSMIC	9.540	Down-regulation
Atypical_PIKK_ATM_ATM_ST	Q8IY92	SLX4	Q13315	ATM	S1398	D1400N	1400	Missense	proximal	2	no	10.311	9.290	EPSD	TCGA;ICGC;COSMIC	9.540	Loss
Atypical_PIKK_ATM_ATM_ST	Q8IY92	SLX4	Q13315	ATM	S1398	E1403K	1403	Missense	distal	5	no	10.311	10.486	EPSD	TCGA;ICGC;COSMIC	9.540	Up-regulation
Atypical_PIKK_ATM_ATM_ST	Q8IY92	SLX4	Q13315	ATM	S1455	A1461V	1461	Missense	distal	6	no	9.774	9.744	EPSD	TCGA;ICGC;COSMIC	9.540	Down-regulation
Atypical_PIKK_ATM_ATM_ST	Q8IY92	SLX4	Q13315	ATM	S1455	A1462T	1462	Missense	distal	7	no	9.774	9.760	EPSD	TCGA;ICGC;COSMIC	9.540	Down-regulation
Atypical_PIKK_ATM_ATM_ST	Q8IY92	SLX4	Q13315	ATM	S1464	A1461V	1461	Missense	distal	-3	no	9.209	10.072	EPSD	TCGA;ICGC;COSMIC	9.540	Gain
Atypical_PIKK_ATM_ATM_ST	Q8IY92	SLX4	Q13315	ATM	T1484	P1477S	1477	Missense	distal	-7	no	9.485	9.721	EPSD	TCGA;ICGC;COSMIC	9.540	Gain
Atypical_PIKK_ATM_ATM_ST	Q8IY92	SLX4	Q13315	ATM	T1484	G1480E	1480	Missense	distal	-4	no	9.485	10.552	EPSD	TCGA;ICGC;COSMIC	9.540	Gain
Atypical_PIKK_ATM_ATM_ST	Q8IY92	SLX4	Q13315	ATM	S1608	S1608L	1608	Missense	central	0	yes	9.763	0.000	EPSD	TCGA;ICGC;COSMIC	9.540	Loss
Atypical_PIKK_ATM_ATM_ST	Q8IY92	SLX4	Q13315	ATM	S1608	S1610F	1610	Missense	proximal	2	no	9.763	8.284	EPSD	TCGA;ICGC;COSMIC	9.540	Loss
Atypical_PIKK_ATM_ATM_ST	Q8IY92	SLX4	Q13315	ATM	S1608	S1614I	1614	Missense	distal	6	no	9.763	9.722	EPSD	TCGA;ICGC;COSMIC	9.540	Down-regulation
Atypical_PIKK_ATM_ATM_ST	Q8IY92	SLX4	Q13315	ATM	S1610	S1608L	1608	Missense	proximal	-2	no	9.762	9.372	EPSD	TCGA;ICGC;COSMIC	9.540	Loss
Atypical_PIKK_ATM_ATM_ST	Q8IY92	SLX4	Q13315	ATM	S1610	S1610F	1610	Missense	central	0	yes	9.762	0.000	EPSD	TCGA;ICGC;COSMIC	9.540	Loss
Atypical_PIKK_ATM_ATM_ST	Q8IY92	SLX4	Q13315	ATM	S1610	S1614I	1614	Missense	distal	4	no	9.762	10.425	EPSD	TCGA;ICGC;COSMIC	9.540	Up-regulation
Atypical_PIKK_ATM_ATM_ST	Q8IY92	SLX4	Q13315	ATM	S1614	S1608L	1608	Missense	distal	-6	no	14.582	14.294	EPSD	TCGA;ICGC;COSMIC	9.540	Down-regulation
Atypical_PIKK_ATM_ATM_ST	Q8IY92	SLX4	Q13315	ATM	S1614	S1610F	1610	Missense	distal	-4	no	14.582	13.183	EPSD	TCGA;ICGC;COSMIC	9.540	Down-regulation
Atypical_PIKK_ATM_ATM_ST	Q8IY92	SLX4	Q13315	ATM	S1614	P1619L	1619	Missense	distal	5	no	14.582	14.565	EPSD	TCGA;ICGC;COSMIC;GDSC	9.540	Down-regulation
Atypical_PIKK_ATM_ATM_ST	Q8IY92	SLX4	Q13315	ATM	S1614	S1614I	1614	Missense	central	0	yes	14.582	0.000	EPSD	TCGA;ICGC;COSMIC	9.540	Loss
Atypical_PIKK_ATM_ATM_ST	Q8IY92	SLX4	Q13315	ATM	S1617	S1610F	1610	Missense	distal	-7	no	14.115	13.286	EPSD	TCGA;ICGC;COSMIC	9.540	Down-regulation
Atypical_PIKK_ATM_ATM_ST	Q8IY92	SLX4	Q13315	ATM	S1617	P1619L	1619	Missense	proximal	2	no	14.115	13.326	EPSD	TCGA;ICGC;COSMIC;GDSC	9.540	Down-regulation
Atypical_PIKK_ATM_ATM_ST	Q8IY92	SLX4	Q13315	ATM	S1617	A1623V	1623	Missense	distal	6	no	14.115	14.085	EPSD	TCGA;ICGC;COSMIC	9.540	Down-regulation
Atypical_PIKK_ATM_ATM_ST	Q8IY92	SLX4	Q13315	ATM	S1617	S1614I	1614	Missense	distal	-3	no	14.115	14.785	EPSD	TCGA;ICGC;COSMIC	9.540	Up-regulation
Atypical_PIKK_ATM_ATM_ST	Q8IY92	SLX4	Q13315	ATM	S1631	Q1627H	1627	Missense	distal	-4	no	13.652	13.417	PhosphoSitePlus;EPSD	TCGA;ICGC;COSMIC	9.540	Down-regulation
Atypical_PIKK_ATM_ATM_ST	Q8IY92	SLX4	Q13315	ATM	S1631	K1635E	1635	Missense	distal	4	no	13.652	13.274	PhosphoSitePlus;EPSD	TCGA;ICGC;COSMIC	9.540	Down-regulation
Atypical_PIKK_ATM_ATM_ST	Q8IY92	SLX4	Q13315	ATM	S1681	S1681L	1681	Missense	central	0	yes	10.439	0.000	EPSD	TCGA;ICGC;COSMIC	9.540	Loss
Atypical_PIKK_ATM_ATM_ST	Q8IY92	SLX4	Q13315	ATM	S1716	C1722S	1722	Missense	distal	6	no	14.699	14.772	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	9.540	Up-regulation
Atypical_PIKK_ATM_ATM_ST	Q9UGP5	POLL	Q13315	ATM	S167	A165T	165	Missense	proximal	-2	no	10.198	10.298	EPSD	TCGA;ICGC	9.540	Up-regulation
Atypical_PIKK_ATM_ATM_ST	Q9UGP5	POLL	Q13315	ATM	S167	P168S	168	Missense	proximal	1	no	10.198	3.222	EPSD	TCGA;ICGC;COSMIC	9.540	Loss
Atypical_PIKK_ATM_ATM_ST	Q9UGP5	POLL	Q13315	ATM	S230	P231L	231	Missense	proximal	1	no	10.644	9.089	EPSD	TCGA;COSMIC	9.540	Loss
Atypical_PIKK_ATM_ATM_ST	Q9UGP5	POLL	Q13315	ATM	S230	A232T	232	Missense	proximal	2	no	10.644	10.965	EPSD	TCGA;ICGC;COSMIC	9.540	Up-regulation
Atypical_PIKK_ATM_ATM_ST	Q9UGP5	POLL	Q13315	ATM	S526	M525T	525	Missense	proximal	-1	no	9.797	10.098	EPSD	TCGA;ICGC;COSMIC	9.540	Up-regulation
Atypical_PIKK_ATM_ATM_ST	Q9UGP5	POLL	Q13315	ATM	S526	A531V	531	Missense	distal	5	no	9.797	9.961	EPSD	TCGA;ICGC;COSMIC	9.540	Up-regulation
Atypical_PIKK_ATM_ATM_ST	Q9UGP5	POLL	Q13315	ATM	S526	L532F	532	Missense	distal	6	no	9.797	9.777	EPSD	TCGA;ICGC	9.540	Down-regulation
Atypical_PIKK_ATM_ATM_ST	P60484	PTEN	Q13315	ATM	S113	L112P	112	Missense	proximal	-1	no	12.108	11.950	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	9.540	Down-regulation
Atypical_PIKK_ATM_ATM_ST	P60484	PTEN	Q13315	ATM	S113	D107H	107	Missense	distal	-6	no	12.108	11.955	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	9.540	Down-regulation
Atypical_PIKK_ATM_ATM_ST	P60484	PTEN	Q13315	ATM	S113	W111R	111	Missense	proximal	-2	no	12.108	12.159	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC;GDSC;CCLE	9.540	Up-regulation
Atypical_PIKK_ATM_ATM_ST	P60484	PTEN	Q13315	ATM	S113	D109N	109	Missense	distal	-4	no	12.108	11.184	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	9.540	Down-regulation
Atypical_PIKK_ATM_ATM_ST	P60484	PTEN	Q13315	ATM	S113	D107Y	107	Missense	distal	-6	no	12.108	11.885	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	9.540	Down-regulation
Atypical_PIKK_ATM_ATM_ST	P60484	PTEN	Q13315	ATM	S113	D107N	107	Missense	distal	-6	no	12.108	12.019	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	9.540	Down-regulation
Atypical_PIKK_ATM_ATM_ST	P60484	PTEN	Q13315	ATM	S113	V119F	119	Missense	distal	6	no	12.108	12.056	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	9.540	Down-regulation
Atypical_PIKK_ATM_ATM_ST	P60484	PTEN	Q13315	ATM	S113	L108F	108	Missense	distal	-5	no	12.108	12.408	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	9.540	Up-regulation
Atypical_PIKK_ATM_ATM_ST	P60484	PTEN	Q13315	ATM	S113	L108P	108	Missense	distal	-5	no	12.108	12.088	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	9.540	Down-regulation
Atypical_PIKK_ATM_ATM_ST	P60484	PTEN	Q13315	ATM	S113	L112V	112	Missense	proximal	-1	no	12.108	11.819	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	9.540	Down-regulation
Atypical_PIKK_ATM_ATM_ST	P60484	PTEN	Q13315	ATM	S170	R173C	173	Missense	distal	3	no	12.740	12.976	EPSD	TCGA;ICGC;COSMIC;GDSC;CCLE	9.540	Up-regulation
Atypical_PIKK_ATM_ATM_ST	P60484	PTEN	Q13315	ATM	S170	T167A	167	Missense	distal	-3	no	12.740	12.362	EPSD	TCGA;ICGC;COSMIC;GDSC;CCLE	9.540	Down-regulation
Atypical_PIKK_ATM_ATM_ST	P60484	PTEN	Q13315	ATM	S170	T167S	167	Missense	distal	-3	no	12.740	12.808	EPSD	TCGA;ICGC;COSMIC	9.540	Up-regulation
Atypical_PIKK_ATM_ATM_ST	P60484	PTEN	Q13315	ATM	S170	R173H	173	Missense	distal	3	no	12.740	12.778	EPSD	TCGA;ICGC;COSMIC;GDSC;CCLE	9.540	Up-regulation
Atypical_PIKK_ATM_ATM_ST	P60484	PTEN	Q13315	ATM	S170	S170N	170	Missense	central	0	yes	12.740	0.000	EPSD	TCGA;ICGC;COSMIC	9.540	Loss
Atypical_PIKK_ATM_ATM_ST	P60484	PTEN	Q13315	ATM	S170	G165E	165	Missense	distal	-5	no	12.740	12.520	EPSD	TCGA;ICGC;COSMIC	9.540	Down-regulation
Atypical_PIKK_ATM_ATM_ST	P60484	PTEN	Q13315	ATM	S170	S170G	170	Missense	central	0	yes	12.740	0.000	EPSD	TCGA;ICGC;COSMIC	9.540	Loss
Atypical_PIKK_ATM_ATM_ST	P60484	PTEN	Q13315	ATM	S170	Q171K	171	Missense	proximal	1	no	12.740	5.892	EPSD	TCGA;ICGC;COSMIC	9.540	Loss
Atypical_PIKK_ATM_ATM_ST	P60484	PTEN	Q13315	ATM	S170	S170R	170	Missense	central	0	yes	12.740	0.000	EPSD	TCGA;ICGC;COSMIC	9.540	Loss
Atypical_PIKK_ATM_ATM_ST	P60484	PTEN	Q13315	ATM	S170	S170I	170	Missense	central	0	yes	12.740	0.000	EPSD	TCGA;ICGC;COSMIC	9.540	Loss
Atypical_PIKK_ATM_ATM_ST	P60484	PTEN	Q13315	ATM	S170	Y177F	177	Missense	distal	7	no	12.740	12.766	EPSD	TCGA;ICGC;COSMIC	9.540	Up-regulation
Atypical_PIKK_ATM_ATM_ST	P60484	PTEN	Q13315	ATM	S170	T167N	167	Missense	distal	-3	no	12.740	12.781	EPSD	TCGA;ICGC;COSMIC	9.540	Up-regulation
Atypical_PIKK_ATM_ATM_ST	P60484	PTEN	Q13315	ATM	S170	Q171R	171	Missense	proximal	1	no	12.740	6.089	EPSD	TCGA;ICGC;COSMIC	9.540	Loss
Atypical_PIKK_ATM_ATM_ST	P60484	PTEN	Q13315	ATM	S170	G165R	165	Missense	distal	-5	no	12.740	12.761	EPSD	TCGA;ICGC;COSMIC	9.540	Up-regulation
Atypical_PIKK_ATM_ATM_ST	P60484	PTEN	Q13315	ATM	S170	R173L	173	Missense	distal	3	no	12.740	12.837	EPSD	TCGA;ICGC;COSMIC	9.540	Up-regulation
Atypical_PIKK_ATM_ATM_ST	P60484	PTEN	Q13315	ATM	S170	Q171E	171	Missense	proximal	1	no	12.740	6.843	EPSD	TCGA;ICGC;COSMIC	9.540	Loss
Atypical_PIKK_ATM_ATM_ST	P60484	PTEN	Q13315	ATM	S170	Y177D	177	Missense	distal	7	no	12.740	12.714	EPSD	TCGA;ICGC;COSMIC	9.540	Down-regulation
Atypical_PIKK_ATM_ATM_ST	P60484	PTEN	Q13315	ATM	T232	R233Q	233	Missense	proximal	1	no	5.070	11.721	EPSD	TCGA;ICGC;COSMIC;GDSC;CCLE	9.540	Gain
Atypical_PIKK_ATM_ATM_ST	P60484	PTEN	Q13315	ATM	T366	E373K	373	Missense	distal	7	no	12.659	12.686	EPSD	TCGA;ICGC	9.540	Up-regulation
Atypical_PIKK_ATM_ATM_ST	P60484	PTEN	Q13315	ATM	T366	N372D	372	Missense	distal	6	no	12.659	12.647	EPSD	TCGA;ICGC;COSMIC	9.540	Down-regulation
Atypical_PIKK_ATM_ATM_ST	P60484	PTEN	Q13315	ATM	S370	E373K	373	Missense	distal	3	no	10.559	10.848	EPSD	TCGA;ICGC	9.540	Up-regulation
Atypical_PIKK_ATM_ATM_ST	P60484	PTEN	Q13315	ATM	S370	N372D	372	Missense	proximal	2	no	10.559	11.580	EPSD	TCGA;ICGC;COSMIC	9.540	Up-regulation
Atypical_PIKK_ATM_ATM_ST	P60484	PTEN	Q13315	ATM	T398	E394K	394	Missense	distal	-4	no	15.262	14.290	PhosphoSitePlus;EPSD	TCGA;ICGC;COSMIC	9.540	Down-regulation
Atypical_PIKK_ATM_ATM_ST	P23025	XPA	Q13315	ATM	S173	H172Y	172	Missense	proximal	-1	no	13.775	13.931	EPSD;PhosphoSitePlus	TCGA;ICGC	9.540	Up-regulation
Atypical_PIKK_ATM_ATM_ST	P23025	XPA	Q13315	ATM	S196	S190F	190	Missense	distal	-6	no	15.823	15.291	PhosphoSitePlus;EPSD	TCGA;ICGC;COSMIC	9.540	Down-regulation
Atypical_PIKK_ATM_ATM_ST	P16220	CREB1	Q13315	ATM	T100	S103A	103	Missense	distal	3	no	12.790	12.845	EPSD;PhosphoSitePlus	TCGA;COSMIC	9.540	Up-regulation
Atypical_PIKK_ATM_ATM_ST	P16220	CREB1	Q13315	ATM	S111	D116G	116	Missense	distal	5	no	15.623	15.715	EPSD;PhosphoSitePlus	TCGA;COSMIC	9.540	Up-regulation
Atypical_PIKK_ATM_ATM_ST	P16220	CREB1	Q13315	ATM	S111	Q112H	112	Missense	proximal	1	no	15.623	0.715	EPSD;PhosphoSitePlus	TCGA;COSMIC	9.540	Loss
Atypical_PIKK_ATM_ATM_ST	P16220	CREB1	Q13315	ATM	S121	D116G	116	Missense	distal	-5	no	14.409	14.675	EPSD;PhosphoSitePlus	TCGA;COSMIC	9.540	Up-regulation
Atypical_PIKK_ATM_ATM_ST	P16220	CREB1	Q13315	ATM	S121	L128I	128	Missense	distal	7	no	14.409	14.421	EPSD;PhosphoSitePlus	TCGA;COSMIC	9.540	Up-regulation
Atypical_PIKK_ATM_ATM_ST	P16220	CREB1	Q13315	ATM	S133	L128I	128	Missense	distal	-5	no	11.625	11.717	PhosphoSitePlus;EPSD	TCGA;COSMIC	9.540	Up-regulation
Atypical_PIKK_ATM_ATM_ST	P16220	CREB1	Q13315	ATM	S156	E152Q	152	Missense	distal	-4	no	9.858	9.134	EPSD	TCGA;ICGC;COSMIC	9.540	Loss
Atypical_PIKK_ATM_ATM_ST	P35637	FUS	Q13315	ATM	S26	S29N	29	Missense	distal	3	no	15.651	15.852	EPSD	TCGA;ICGC	9.540	Up-regulation
Atypical_PIKK_ATM_ATM_ST	P35637	FUS	Q13315	ATM	S30	S29N	29	Missense	proximal	-1	no	15.895	15.840	EPSD	TCGA;ICGC	9.540	Down-regulation
Atypical_PIKK_ATM_ATM_ST	P35637	FUS	Q13315	ATM	S42	D46H	46	Missense	distal	4	no	14.065	13.975	PhosphoSitePlus	TCGA;ICGC;COSMIC	9.540	Down-regulation
Atypical_PIKK_ATM_ATM_ST	P35637	FUS	Q13315	ATM	S131	Y136C	136	Missense	distal	5	no	14.789	14.951	EPSD	TCGA;COSMIC	9.540	Up-regulation
Atypical_PIKK_ATM_ATM_ST	P35637	FUS	Q13315	ATM	S277	E278K	278	Missense	proximal	1	no	10.345	9.394	EPSD	TCGA;ICGC;COSMIC	9.540	Loss
Atypical_PIKK_ATM_ATM_ST	P35637	FUS	Q13315	ATM	S282	T286I	286	Missense	distal	4	no	10.165	10.741	EPSD	TCGA;ICGC;COSMIC	9.540	Up-regulation
Atypical_PIKK_ATM_ATM_ST	P35637	FUS	Q13315	ATM	S282	E278K	278	Missense	distal	-4	no	10.165	9.194	EPSD	TCGA;ICGC;COSMIC	9.540	Loss
Atypical_PIKK_ATM_ATM_ST	Q7Z6Z7	HUWE1	Q13315	ATM	T161	R162Q	162	Missense	proximal	1	no	7.755	14.406	EPSD	TCGA;ICGC;COSMIC	9.540	Gain
Atypical_PIKK_ATM_ATM_ST	Q7Z6Z7	HUWE1	Q13315	ATM	T485	T484A	484	Missense	proximal	-1	no	14.849	14.678	EPSD	TCGA	9.540	Down-regulation
Atypical_PIKK_ATM_ATM_ST	Q7Z6Z7	HUWE1	Q13315	ATM	T485	T485A	485	Missense	central	0	yes	14.849	0.000	EPSD	TCGA;ICGC	9.540	Loss
Atypical_PIKK_ATM_ATM_ST	Q7Z6Z7	HUWE1	Q13315	ATM	T485	G488E	488	Missense	distal	3	no	14.849	14.542	EPSD	TCGA;ICGC;COSMIC	9.540	Down-regulation
Atypical_PIKK_ATM_ATM_ST	Q7Z6Z7	HUWE1	Q13315	ATM	T485	E490K	490	Missense	distal	5	no	14.849	15.023	EPSD	TCGA;ICGC	9.540	Up-regulation
Atypical_PIKK_ATM_ATM_ST	Q7Z6Z7	HUWE1	Q13315	ATM	T744	M738I	738	Missense	distal	-6	no	15.443	15.287	EPSD	TCGA;ICGC	9.540	Down-regulation
Atypical_PIKK_ATM_ATM_ST	Q7Z6Z7	HUWE1	Q13315	ATM	T744	E750Q	750	Missense	distal	6	no	15.443	15.396	EPSD	TCGA;ICGC;COSMIC	9.540	Down-regulation
Atypical_PIKK_ATM_ATM_ST	Q7Z6Z7	HUWE1	Q13315	ATM	T744	A737V	737	Missense	distal	-7	no	15.443	15.059	EPSD	TCGA;ICGC;COSMIC	9.540	Down-regulation
Atypical_PIKK_ATM_ATM_ST	Q7Z6Z7	HUWE1	Q13315	ATM	T749	E750Q	750	Missense	proximal	1	no	7.542	13.439	EPSD	TCGA;ICGC;COSMIC	9.540	Gain
Atypical_PIKK_ATM_ATM_ST	Q7Z6Z7	HUWE1	Q13315	ATM	S854	S850A	850	Missense	distal	-4	no	10.174	9.665	EPSD	TCGA;ICGC;COSMIC	9.540	Down-regulation
Atypical_PIKK_ATM_ATM_ST	Q7Z6Z7	HUWE1	Q13315	ATM	S927	S921F	921	Missense	distal	-6	no	14.403	13.871	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	9.540	Down-regulation
Atypical_PIKK_ATM_ATM_ST	Q7Z6Z7	HUWE1	Q13315	ATM	S927	V933I	933	Missense	distal	6	no	14.403	14.386	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	9.540	Down-regulation
Atypical_PIKK_ATM_ATM_ST	Q7Z6Z7	HUWE1	Q13315	ATM	T1005	E1010Q	1010	Missense	distal	5	no	12.495	12.720	EPSD	TCGA;ICGC;COSMIC	9.540	Up-regulation
Atypical_PIKK_ATM_ATM_ST	Q7Z6Z7	HUWE1	Q13315	ATM	T1005	M1001V	1001	Missense	distal	-4	no	12.495	12.514	EPSD	TCGA;ICGC;COSMIC	9.540	Up-regulation
Atypical_PIKK_ATM_ATM_ST	Q7Z6Z7	HUWE1	Q13315	ATM	S1183	E1184Q	1184	Missense	proximal	1	no	6.866	12.763	EPSD	TCGA;ICGC;COSMIC	9.540	Gain
Atypical_PIKK_ATM_ATM_ST	Q7Z6Z7	HUWE1	Q13315	ATM	S1218	L1216I	1216	Missense	proximal	-2	no	10.342	10.043	EPSD	TCGA;ICGC;COSMIC	9.540	Down-regulation
Atypical_PIKK_ATM_ATM_ST	Q7Z6Z7	HUWE1	Q13315	ATM	S1218	T1214M	1214	Missense	distal	-4	no	10.342	9.718	EPSD	TCGA;ICGC;COSMIC	9.540	Down-regulation
Atypical_PIKK_ATM_ATM_ST	Q7Z6Z7	HUWE1	Q13315	ATM	S1370	R1377T	1377	Missense	distal	7	no	10.535	10.517	EPSD	TCGA;ICGC;COSMIC	9.540	Down-regulation
Atypical_PIKK_ATM_ATM_ST	Q7Z6Z7	HUWE1	Q13315	ATM	S1370	L1367F	1367	Missense	distal	-3	no	10.535	11.398	EPSD	TCGA;ICGC;COSMIC	9.540	Up-regulation
Atypical_PIKK_ATM_ATM_ST	Q7Z6Z7	HUWE1	Q13315	ATM	S1505	E1512Q	1512	Missense	distal	7	no	10.056	10.070	EPSD	TCGA;ICGC;COSMIC	9.540	Up-regulation
Atypical_PIKK_ATM_ATM_ST	Q7Z6Z7	HUWE1	Q13315	ATM	S1505	A1499D	1499	Missense	distal	-6	no	10.056	10.049	EPSD	TCGA;ICGC;COSMIC	9.540	Down-regulation
Atypical_PIKK_ATM_ATM_ST	Q7Z6Z7	HUWE1	Q13315	ATM	S1511	E1512Q	1512	Missense	proximal	1	no	7.311	13.208	EPSD	TCGA;ICGC;COSMIC	9.540	Gain
Atypical_PIKK_ATM_ATM_ST	Q7Z6Z7	HUWE1	Q13315	ATM	S1707	K1713E	1713	Missense	distal	6	no	9.888	9.934	EPSD	TCGA;ICGC;COSMIC	9.540	Up-regulation
Atypical_PIKK_ATM_ATM_ST	Q7Z6Z7	HUWE1	Q13315	ATM	S1707	E1701D	1701	Missense	distal	-6	no	9.888	9.674	EPSD	TCGA;ICGC;COSMIC	9.540	Down-regulation
Atypical_PIKK_ATM_ATM_ST	Q7Z6Z7	HUWE1	Q13315	ATM	S1707	S1707N	1707	Missense	central	0	yes	9.888	0.000	EPSD	TCGA;ICGC	9.540	Loss
Atypical_PIKK_ATM_ATM_ST	Q7Z6Z7	HUWE1	Q13315	ATM	S1736	T1729A	1729	Missense	distal	-7	no	9.702	9.687	EPSD	TCGA;ICGC	9.540	Down-regulation
Atypical_PIKK_ATM_ATM_ST	Q7Z6Z7	HUWE1	Q13315	ATM	T2003	D2002N	2002	Missense	proximal	-1	no	15.824	15.823	EPSD	TCGA;ICGC;COSMIC;GDSC;CCLE	9.540	Down-regulation
Atypical_PIKK_ATM_ATM_ST	Q7Z6Z7	HUWE1	Q13315	ATM	T2003	R1996H	1996	Missense	distal	-7	no	15.824	15.909	EPSD	TCGA;ICGC;COSMIC	9.540	Up-regulation
Atypical_PIKK_ATM_ATM_ST	Q7Z6Z7	HUWE1	Q13315	ATM	T2003	Q1997H	1997	Missense	distal	-6	no	15.824	15.681	EPSD	TCGA;ICGC;COSMIC	9.540	Down-regulation
Atypical_PIKK_ATM_ATM_ST	Q7Z6Z7	HUWE1	Q13315	ATM	T2003	R1996L	1996	Missense	distal	-7	no	15.824	15.634	EPSD	TCGA	9.540	Down-regulation
Atypical_PIKK_ATM_ATM_ST	Q7Z6Z7	HUWE1	Q13315	ATM	T2003	T2003M	2003	Missense	central	0	yes	15.824	0.000	EPSD	TCGA;COSMIC	9.540	Loss
Atypical_PIKK_ATM_ATM_ST	Q7Z6Z7	HUWE1	Q13315	ATM	S2052	Q2057P	2057	Missense	distal	5	no	9.649	9.777	EPSD	TCGA;ICGC;COSMIC	9.540	Up-regulation
Atypical_PIKK_ATM_ATM_ST	Q7Z6Z7	HUWE1	Q13315	ATM	S2339	E2335Q	2335	Missense	distal	-4	no	16.456	15.733	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	9.540	Down-regulation
Atypical_PIKK_ATM_ATM_ST	Q7Z6Z7	HUWE1	Q13315	ATM	S2339	E2345K	2345	Missense	distal	6	no	16.456	16.410	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	9.540	Down-regulation
Atypical_PIKK_ATM_ATM_ST	Q7Z6Z7	HUWE1	Q13315	ATM	S2377	S2372N	2372	Missense	distal	-5	no	15.651	15.623	EPSD	TCGA;ICGC;COSMIC	9.540	Down-regulation
Atypical_PIKK_ATM_ATM_ST	Q7Z6Z7	HUWE1	Q13315	ATM	S2391	E2385K	2385	Missense	distal	-6	no	13.767	13.466	EPSD	TCGA;ICGC;COSMIC	9.540	Down-regulation
Atypical_PIKK_ATM_ATM_ST	Q7Z6Z7	HUWE1	Q13315	ATM	S2391	A2386D	2386	Missense	distal	-5	no	13.767	13.563	EPSD	TCGA;ICGC;COSMIC	9.540	Down-regulation
Atypical_PIKK_ATM_ATM_ST	Q7Z6Z7	HUWE1	Q13315	ATM	S2391	A2386G	2386	Missense	distal	-5	no	13.767	13.829	EPSD	TCGA;ICGC;COSMIC	9.540	Up-regulation
Atypical_PIKK_ATM_ATM_ST	Q7Z6Z7	HUWE1	Q13315	ATM	S2477	R2484C	2484	Missense	distal	7	no	12.054	12.071	EPSD	TCGA;ICGC;COSMIC	9.540	Up-regulation
Atypical_PIKK_ATM_ATM_ST	Q7Z6Z7	HUWE1	Q13315	ATM	T2540	R2545H	2545	Missense	distal	5	no	12.010	11.985	EPSD	TCGA;COSMIC	9.540	Down-regulation
Atypical_PIKK_ATM_ATM_ST	Q7Z6Z7	HUWE1	Q13315	ATM	T2540	R2545C	2545	Missense	distal	5	no	12.010	12.071	EPSD	TCGA;ICGC;COSMIC	9.540	Up-regulation
Atypical_PIKK_ATM_ATM_ST	Q7Z6Z7	HUWE1	Q13315	ATM	T2540	R2538H	2538	Missense	proximal	-2	no	12.010	12.026	EPSD	TCGA;ICGC;COSMIC	9.540	Up-regulation
Atypical_PIKK_ATM_ATM_ST	Q7Z6Z7	HUWE1	Q13315	ATM	S2546	R2545H	2545	Missense	proximal	-1	no	12.023	12.193	EPSD	TCGA;COSMIC	9.540	Up-regulation
Atypical_PIKK_ATM_ATM_ST	Q7Z6Z7	HUWE1	Q13315	ATM	S2546	R2545C	2545	Missense	proximal	-1	no	12.023	12.197	EPSD	TCGA;ICGC;COSMIC	9.540	Up-regulation
Atypical_PIKK_ATM_ATM_ST	Q7Z6Z7	HUWE1	Q13315	ATM	S2546	R2548M	2548	Missense	proximal	2	no	12.023	11.963	EPSD	TCGA;ICGC;COSMIC	9.540	Down-regulation
Atypical_PIKK_ATM_ATM_ST	Q7Z6Z7	HUWE1	Q13315	ATM	S2619	E2622K	2622	Missense	distal	3	no	9.348	9.637	EPSD	TCGA;ICGC;COSMIC	9.540	Gain
Atypical_PIKK_ATM_ATM_ST	Q7Z6Z7	HUWE1	Q13315	ATM	S2636	T2635S	2635	Missense	proximal	-1	no	14.756	14.746	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	9.540	Down-regulation
Atypical_PIKK_ATM_ATM_ST	Q7Z6Z7	HUWE1	Q13315	ATM	S2636	Q2631R	2631	Missense	distal	-5	no	14.756	14.965	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	9.540	Up-regulation
Atypical_PIKK_ATM_ATM_ST	Q7Z6Z7	HUWE1	Q13315	ATM	S2636	S2642F	2642	Missense	distal	6	no	14.756	14.680	EPSD;PhosphoSitePlus	TCGA;ICGC	9.540	Down-regulation
Atypical_PIKK_ATM_ATM_ST	Q7Z6Z7	HUWE1	Q13315	ATM	T2640	T2635S	2635	Missense	distal	-5	no	9.524	9.613	EPSD	TCGA;ICGC;COSMIC	9.540	Gain
Atypical_PIKK_ATM_ATM_ST	Q7Z6Z7	HUWE1	Q13315	ATM	T2640	A2647V	2647	Missense	distal	7	no	9.524	9.542	EPSD	TCGA;ICGC	9.540	Gain
Atypical_PIKK_ATM_ATM_ST	Q7Z6Z7	HUWE1	Q13315	ATM	T2821	M2823I	2823	Missense	proximal	2	no	13.010	13.383	EPSD	TCGA;ICGC;COSMIC	9.540	Up-regulation
Atypical_PIKK_ATM_ATM_ST	Q7Z6Z7	HUWE1	Q13315	ATM	S2826	I2831V	2831	Missense	distal	5	no	9.681	9.684	EPSD	TCGA;ICGC;COSMIC	9.540	Up-regulation
Atypical_PIKK_ATM_ATM_ST	Q7Z6Z7	HUWE1	Q13315	ATM	S2826	M2823I	2823	Missense	distal	-3	no	9.681	9.996	EPSD	TCGA;ICGC;COSMIC	9.540	Up-regulation
Atypical_PIKK_ATM_ATM_ST	Q7Z6Z7	HUWE1	Q13315	ATM	S2923	S2917R	2917	Missense	distal	-6	no	10.474	10.293	EPSD	TCGA;ICGC;COSMIC	9.540	Down-regulation
Atypical_PIKK_ATM_ATM_ST	Q7Z6Z7	HUWE1	Q13315	ATM	S2923	D2930N	2930	Missense	distal	7	no	10.474	10.480	EPSD	TCGA;ICGC;COSMIC	9.540	Up-regulation
Atypical_PIKK_ATM_ATM_ST	Q7Z6Z7	HUWE1	Q13315	ATM	S2923	D2916G	2916	Missense	distal	-7	no	10.474	10.183	EPSD	TCGA;ICGC	9.540	Down-regulation
Atypical_PIKK_ATM_ATM_ST	Q7Z6Z7	HUWE1	Q13315	ATM	S2923	S2927F	2927	Missense	distal	4	no	10.474	11.301	EPSD	TCGA;ICGC;COSMIC	9.540	Up-regulation
Atypical_PIKK_ATM_ATM_ST	Q7Z6Z7	HUWE1	Q13315	ATM	S2940	R2941Q	2941	Missense	proximal	1	no	8.559	15.210	EPSD	TCGA;ICGC;COSMIC	9.540	Gain
Atypical_PIKK_ATM_ATM_ST	Q7Z6Z7	HUWE1	Q13315	ATM	S3018	E3020K	3020	Missense	proximal	2	no	11.802	10.472	EPSD	TCGA;ICGC;COSMIC	9.540	Down-regulation
Atypical_PIKK_ATM_ATM_ST	Q7Z6Z7	HUWE1	Q13315	ATM	S3052	D3057Y	3057	Missense	distal	5	no	9.943	9.921	EPSD	TCGA;ICGC;COSMIC	9.540	Down-regulation
Atypical_PIKK_ATM_ATM_ST	Q7Z6Z7	HUWE1	Q13315	ATM	S3052	A3050V	3050	Missense	proximal	-2	no	9.943	9.466	EPSD	TCGA;ICGC;COSMIC	9.540	Loss
Atypical_PIKK_ATM_ATM_ST	Q7Z6Z7	HUWE1	Q13315	ATM	S3127	S3122F	3122	Missense	distal	-5	no	9.827	10.150	EPSD	TCGA;ICGC;COSMIC	9.540	Up-regulation
Atypical_PIKK_ATM_ATM_ST	Q7Z6Z7	HUWE1	Q13315	ATM	S3127	R3133H	3133	Missense	distal	6	no	9.827	9.811	EPSD	TCGA;ICGC;COSMIC;GDSC;CCLE	9.540	Down-regulation
Atypical_PIKK_ATM_ATM_ST	Q7Z6Z7	HUWE1	Q13315	ATM	S3127	R3126Q	3126	Missense	proximal	-1	no	9.827	10.134	EPSD	TCGA;ICGC;COSMIC	9.540	Up-regulation
Atypical_PIKK_ATM_ATM_ST	Q7Z6Z7	HUWE1	Q13315	ATM	S3248	S3248N	3248	Missense	central	0	yes	13.231	0.000	EPSD	TCGA;ICGC;COSMIC	9.540	Loss
Atypical_PIKK_ATM_ATM_ST	Q7Z6Z7	HUWE1	Q13315	ATM	S3373	S3379F	3379	Missense	distal	6	no	10.639	10.563	EPSD	TCGA;ICGC	9.540	Down-regulation
Atypical_PIKK_ATM_ATM_ST	Q7Z6Z7	HUWE1	Q13315	ATM	S3373	R3367M	3367	Missense	distal	-6	no	10.639	10.574	EPSD	TCGA;ICGC;COSMIC	9.540	Down-regulation
Atypical_PIKK_ATM_ATM_ST	Q7Z6Z7	HUWE1	Q13315	ATM	S3373	G3368D	3368	Missense	distal	-5	no	10.639	10.373	EPSD	TCGA	9.540	Down-regulation
Atypical_PIKK_ATM_ATM_ST	Q7Z6Z7	HUWE1	Q13315	ATM	S3377	S3379F	3379	Missense	proximal	2	no	16.606	15.128	EPSD;PhosphoSitePlus	TCGA;ICGC	9.540	Down-regulation
Atypical_PIKK_ATM_ATM_ST	Q7Z6Z7	HUWE1	Q13315	ATM	S3377	S3381G	3381	Missense	distal	4	no	16.606	16.735	EPSD;PhosphoSitePlus	TCGA	9.540	Up-regulation
Atypical_PIKK_ATM_ATM_ST	Q7Z6Z7	HUWE1	Q13315	ATM	S3380	S3381G	3381	Missense	proximal	1	no	5.272	10.576	EPSD	TCGA	9.540	Gain
Atypical_PIKK_ATM_ATM_ST	Q7Z6Z7	HUWE1	Q13315	ATM	S3382	S3379F	3379	Missense	distal	-3	no	8.745	9.816	EPSD	TCGA;ICGC	9.540	Gain
Atypical_PIKK_ATM_ATM_ST	Q7Z6Z7	HUWE1	Q13315	ATM	S3422	S3425N	3425	Missense	distal	3	no	10.803	11.003	EPSD	TCGA;ICGC;COSMIC	9.540	Up-regulation
Atypical_PIKK_ATM_ATM_ST	Q7Z6Z7	HUWE1	Q13315	ATM	S3422	G3419W	3419	Missense	distal	-3	no	10.803	10.835	EPSD	TCGA;ICGC;COSMIC	9.540	Up-regulation
Atypical_PIKK_ATM_ATM_ST	Q7Z6Z7	HUWE1	Q13315	ATM	S3662	E3669K	3669	Missense	distal	7	no	9.935	9.962	EPSD	TCGA;ICGC;COSMIC	9.540	Up-regulation
Atypical_PIKK_ATM_ATM_ST	Q7Z6Z7	HUWE1	Q13315	ATM	S3662	E3668K	3668	Missense	distal	6	no	9.935	9.889	EPSD	TCGA;ICGC;COSMIC	9.540	Down-regulation
Atypical_PIKK_ATM_ATM_ST	Q7Z6Z7	HUWE1	Q13315	ATM	S3662	R3655Q	3655	Missense	distal	-7	no	9.935	10.134	EPSD	TCGA;ICGC;COSMIC;CCLE	9.540	Up-regulation
Atypical_PIKK_ATM_ATM_ST	Q7Z6Z7	HUWE1	Q13315	ATM	S3695	I3692L	3692	Missense	distal	-3	no	13.868	13.408	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	9.540	Down-regulation
Atypical_PIKK_ATM_ATM_ST	Q7Z6Z7	HUWE1	Q13315	ATM	S3695	Q3696H	3696	Missense	proximal	1	no	13.868	-1.041	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	9.540	Loss
Atypical_PIKK_ATM_ATM_ST	Q7Z6Z7	HUWE1	Q13315	ATM	S3695	G3701C	3701	Missense	distal	6	no	13.868	13.815	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	9.540	Down-regulation
Atypical_PIKK_ATM_ATM_ST	Q7Z6Z7	HUWE1	Q13315	ATM	S3797	T3793M	3793	Missense	distal	-4	no	14.874	14.250	PhosphoSitePlus;EPSD	TCGA;ICGC;COSMIC	9.540	Down-regulation
Atypical_PIKK_ATM_ATM_ST	Q7Z6Z7	HUWE1	Q13315	ATM	S3797	A3801V	3801	Missense	distal	4	no	14.874	15.527	PhosphoSitePlus;EPSD	TCGA;ICGC;COSMIC	9.540	Up-regulation
Atypical_PIKK_ATM_ATM_ST	Q7Z6Z7	HUWE1	Q13315	ATM	S3799	T3793M	3793	Missense	distal	-6	no	10.218	10.042	EPSD	TCGA;ICGC;COSMIC	9.540	Down-regulation
Atypical_PIKK_ATM_ATM_ST	Q7Z6Z7	HUWE1	Q13315	ATM	S3799	A3801V	3801	Missense	proximal	2	no	10.218	9.909	EPSD	TCGA;ICGC;COSMIC	9.540	Down-regulation
Atypical_PIKK_ATM_ATM_ST	Q7Z6Z7	HUWE1	Q13315	ATM	S3808	A3801V	3801	Missense	distal	-7	no	11.029	10.645	EPSD	TCGA;ICGC;COSMIC	9.540	Down-regulation
Atypical_PIKK_ATM_ATM_ST	Q7Z6Z7	HUWE1	Q13315	ATM	S3808	P3815S	3815	Missense	distal	7	no	11.029	11.010	EPSD	TCGA;ICGC	9.540	Down-regulation
Atypical_PIKK_ATM_ATM_ST	Q7Z6Z7	HUWE1	Q13315	ATM	T3822	D3828Y	3828	Missense	distal	6	no	14.516	14.497	EPSD	TCGA;ICGC;COSMIC	9.540	Down-regulation
Atypical_PIKK_ATM_ATM_ST	Q7Z6Z7	HUWE1	Q13315	ATM	T3822	P3815S	3815	Missense	distal	-7	no	14.516	14.752	EPSD	TCGA;ICGC	9.540	Up-regulation
Atypical_PIKK_ATM_ATM_ST	Q7Z6Z7	HUWE1	Q13315	ATM	S3906	A3909V	3909	Missense	distal	3	no	14.815	15.103	EPSD	TCGA;ICGC;COSMIC	9.540	Up-regulation
Atypical_PIKK_ATM_ATM_ST	Q7Z6Z7	HUWE1	Q13315	ATM	S3906	R3904S	3904	Missense	proximal	-2	no	14.815	15.258	EPSD	TCGA;ICGC;COSMIC	9.540	Up-regulation
Atypical_PIKK_ATM_ATM_ST	Q7Z6Z7	HUWE1	Q13315	ATM	S3906	A3909T	3909	Missense	distal	3	no	14.815	14.840	EPSD	TCGA;ICGC;COSMIC	9.540	Up-regulation
Atypical_PIKK_ATM_ATM_ST	Q7Z6Z7	HUWE1	Q13315	ATM	S3919	A3921V	3921	Missense	proximal	2	no	9.662	9.353	EPSD	TCGA;ICGC	9.540	Loss
Atypical_PIKK_ATM_ATM_ST	Q7Z6Z7	HUWE1	Q13315	ATM	S3919	L3923S	3923	Missense	distal	4	no	9.662	9.320	EPSD	TCGA;ICGC;COSMIC	9.540	Loss
Atypical_PIKK_ATM_ATM_ST	Q7Z6Z7	HUWE1	Q13315	ATM	T3927	S3930F	3930	Missense	distal	3	no	9.169	9.751	EPSD	TCGA;ICGC;COSMIC	9.540	Gain
Atypical_PIKK_ATM_ATM_ST	Q7Z6Z7	HUWE1	Q13315	ATM	T3927	L3923S	3923	Missense	distal	-4	no	9.169	10.108	EPSD	TCGA;ICGC;COSMIC	9.540	Gain
Atypical_PIKK_ATM_ATM_ST	Q7Z6Z7	HUWE1	Q13315	ATM	S3930	L3923S	3923	Missense	distal	-7	no	9.112	9.700	EPSD	TCGA;ICGC;COSMIC	9.540	Gain
Atypical_PIKK_ATM_ATM_ST	Q7Z6Z7	HUWE1	Q13315	ATM	S4070	R4071Q	4071	Missense	proximal	1	no	10.787	17.439	EPSD	TCGA;ICGC;COSMIC	9.540	Up-regulation
Atypical_PIKK_ATM_ATM_ST	Q7Z6Z7	HUWE1	Q13315	ATM	S4070	P4076S	4076	Missense	distal	6	no	10.787	10.798	EPSD	TCGA;ICGC;COSMIC	9.540	Up-regulation
Atypical_PIKK_ATM_ATM_ST	Q7Z6Z7	HUWE1	Q13315	ATM	S4070	P4076H	4076	Missense	distal	6	no	10.787	10.765	EPSD	TCGA;ICGC;COSMIC	9.540	Down-regulation
Atypical_PIKK_ATM_ATM_ST	Q15648	MED1	Q13315	ATM	S238	K235R	235	Missense	distal	-3	no	9.252	10.084	EPSD	TCGA;ICGC;COSMIC	9.540	Gain
Atypical_PIKK_ATM_ATM_ST	Q15648	MED1	Q13315	ATM	S387	L382F	382	Missense	distal	-5	no	9.466	9.767	EPSD	TCGA;ICGC;COSMIC	9.540	Gain
Atypical_PIKK_ATM_ATM_ST	Q15648	MED1	Q13315	ATM	S434	E441K	441	Missense	distal	7	no	11.174	11.201	EPSD	TCGA;ICGC;COSMIC	9.540	Up-regulation
Atypical_PIKK_ATM_ATM_ST	Q15648	MED1	Q13315	ATM	S434	S434F	434	Missense	central	0	yes	11.174	0.000	EPSD	TCGA;ICGC;COSMIC	9.540	Loss
Atypical_PIKK_ATM_ATM_ST	Q15648	MED1	Q13315	ATM	S434	R427I	427	Missense	distal	-7	no	11.174	10.908	EPSD	TCGA;ICGC;COSMIC	9.540	Down-regulation
Atypical_PIKK_ATM_ATM_ST	Q15648	MED1	Q13315	ATM	S434	P435L	435	Missense	proximal	1	no	11.174	9.619	EPSD	TCGA;ICGC;COSMIC	9.540	Down-regulation
Atypical_PIKK_ATM_ATM_ST	Q15648	MED1	Q13315	ATM	S434	G436W	436	Missense	proximal	2	no	11.174	10.714	EPSD	TCGA;ICGC;COSMIC	9.540	Down-regulation
Atypical_PIKK_ATM_ATM_ST	Q15648	MED1	Q13315	ATM	T522	P523Q	523	Missense	proximal	1	no	6.898	11.700	EPSD	TCGA;ICGC;COSMIC	9.540	Gain
Atypical_PIKK_ATM_ATM_ST	Q15648	MED1	Q13315	ATM	S599	L604V	604	Missense	distal	5	no	15.395	15.443	EPSD	TCGA;ICGC;COSMIC	9.540	Up-regulation
Atypical_PIKK_ATM_ATM_ST	Q15648	MED1	Q13315	ATM	S621	T628M	628	Missense	distal	7	no	11.383	11.400	EPSD	TCGA;ICGC	9.540	Up-regulation
Atypical_PIKK_ATM_ATM_ST	Q15648	MED1	Q13315	ATM	S621	P625A	625	Missense	distal	4	no	11.383	10.913	EPSD	TCGA;ICGC;COSMIC	9.540	Down-regulation
Atypical_PIKK_ATM_ATM_ST	Q15648	MED1	Q13315	ATM	S621	H627D	627	Missense	distal	6	no	11.383	11.394	EPSD	TCGA;ICGC;COSMIC	9.540	Up-regulation
Atypical_PIKK_ATM_ATM_ST	Q15648	MED1	Q13315	ATM	S719	D725N	725	Missense	distal	6	no	14.366	14.378	EPSD	TCGA;ICGC;COSMIC	9.540	Up-regulation
Atypical_PIKK_ATM_ATM_ST	Q15648	MED1	Q13315	ATM	S719	S714L	714	Missense	distal	-5	no	14.366	14.389	EPSD	TCGA;ICGC;COSMIC	9.540	Up-regulation
Atypical_PIKK_ATM_ATM_ST	Q15648	MED1	Q13315	ATM	S772	R768Q	768	Missense	distal	-4	no	9.612	9.978	EPSD	TCGA;ICGC;COSMIC	9.540	Up-regulation
Atypical_PIKK_ATM_ATM_ST	Q15648	MED1	Q13315	ATM	S816	S810Y	810	Missense	distal	-6	no	14.078	13.828	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	9.540	Down-regulation
Atypical_PIKK_ATM_ATM_ST	Q15648	MED1	Q13315	ATM	S816	Q817K	817	Missense	proximal	1	no	14.078	7.229	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	9.540	Loss
Atypical_PIKK_ATM_ATM_ST	Q15648	MED1	Q13315	ATM	S816	S816Y	816	Missense	central	0	yes	14.078	0.000	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	9.540	Loss
Atypical_PIKK_ATM_ATM_ST	Q15648	MED1	Q13315	ATM	S848	G847R	847	Missense	proximal	-1	no	11.270	11.087	EPSD	TCGA;ICGC;COSMIC	9.540	Down-regulation
Atypical_PIKK_ATM_ATM_ST	Q15648	MED1	Q13315	ATM	S853	G847R	847	Missense	distal	-6	no	9.690	9.712	EPSD	TCGA;ICGC;COSMIC	9.540	Up-regulation
Atypical_PIKK_ATM_ATM_ST	Q15648	MED1	Q13315	ATM	S872	N871S	871	Missense	proximal	-1	no	15.569	15.625	PhosphoSitePlus;EPSD	TCGA;ICGC;COSMIC	9.540	Up-regulation
Atypical_PIKK_ATM_ATM_ST	Q15648	MED1	Q13315	ATM	S872	S876I	876	Missense	distal	4	no	15.569	16.232	PhosphoSitePlus;EPSD	TCGA;ICGC	9.540	Up-regulation
Atypical_PIKK_ATM_ATM_ST	Q15648	MED1	Q13315	ATM	S874	N871S	871	Missense	distal	-3	no	15.554	15.581	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	9.540	Up-regulation
Atypical_PIKK_ATM_ATM_ST	Q15648	MED1	Q13315	ATM	S874	S876I	876	Missense	proximal	2	no	15.554	14.869	EPSD;PhosphoSitePlus	TCGA;ICGC	9.540	Down-regulation
Atypical_PIKK_ATM_ATM_ST	Q15648	MED1	Q13315	ATM	S887	D891G	891	Missense	distal	4	no	16.742	16.663	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	9.540	Down-regulation
Atypical_PIKK_ATM_ATM_ST	Q15648	MED1	Q13315	ATM	S887	S889T	889	Missense	proximal	2	no	16.742	16.480	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	9.540	Down-regulation
Atypical_PIKK_ATM_ATM_ST	Q15648	MED1	Q13315	ATM	S900	Q901R	901	Missense	proximal	1	no	12.661	6.010	EPSD	TCGA;ICGC;COSMIC	9.540	Loss
Atypical_PIKK_ATM_ATM_ST	Q15648	MED1	Q13315	ATM	S1049	S1049C	1049	Missense	central	0	yes	15.150	0.000	EPSD	TCGA;ICGC;COSMIC	9.540	Loss
Atypical_PIKK_ATM_ATM_ST	Q15648	MED1	Q13315	ATM	T1051	S1049C	1049	Missense	proximal	-2	no	9.640	9.178	EPSD	TCGA;ICGC;COSMIC	9.540	Loss
Atypical_PIKK_ATM_ATM_ST	Q15648	MED1	Q13315	ATM	S1081	V1074A	1074	Missense	distal	-7	no	12.074	12.457	EPSD	TCGA;ICGC;COSMIC	9.540	Up-regulation
Atypical_PIKK_ATM_ATM_ST	Q15648	MED1	Q13315	ATM	S1081	P1077S	1077	Missense	distal	-4	no	12.074	12.743	EPSD	TCGA;ICGC;COSMIC	9.540	Up-regulation
Atypical_PIKK_ATM_ATM_ST	Q15648	MED1	Q13315	ATM	S1092	V1089M	1089	Missense	distal	-3	no	10.245	10.182	EPSD	TCGA;ICGC;COSMIC	9.540	Down-regulation
Atypical_PIKK_ATM_ATM_ST	Q15648	MED1	Q13315	ATM	S1092	S1091F	1091	Missense	proximal	-1	no	10.245	9.819	EPSD	TCGA;ICGC;COSMIC	9.540	Down-regulation
Atypical_PIKK_ATM_ATM_ST	Q15648	MED1	Q13315	ATM	S1092	S1099N	1099	Missense	distal	7	no	10.245	10.260	EPSD	TCGA;ICGC	9.540	Up-regulation
Atypical_PIKK_ATM_ATM_ST	Q15648	MED1	Q13315	ATM	S1092	G1093S	1093	Missense	proximal	1	no	10.245	4.942	EPSD	TCGA;ICGC	9.540	Loss
Atypical_PIKK_ATM_ATM_ST	Q15648	MED1	Q13315	ATM	S1094	S1091F	1091	Missense	distal	-3	no	8.913	9.984	EPSD	TCGA;ICGC;COSMIC	9.540	Gain
Atypical_PIKK_ATM_ATM_ST	Q15648	MED1	Q13315	ATM	S1134	Q1135H	1135	Missense	proximal	1	no	14.814	-0.095	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	9.540	Loss
Atypical_PIKK_ATM_ATM_ST	Q15648	MED1	Q13315	ATM	S1134	S1129G	1129	Missense	distal	-5	no	14.814	14.869	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	9.540	Up-regulation
Atypical_PIKK_ATM_ATM_ST	Q15648	MED1	Q13315	ATM	S1134	G1139E	1139	Missense	distal	5	no	14.814	14.465	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	9.540	Down-regulation
Atypical_PIKK_ATM_ATM_ST	Q15648	MED1	Q13315	ATM	S1141	Q1135H	1135	Missense	distal	-6	no	16.267	16.125	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	9.540	Down-regulation
Atypical_PIKK_ATM_ATM_ST	Q15648	MED1	Q13315	ATM	S1141	S1143C	1143	Missense	proximal	2	no	16.267	15.013	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	9.540	Down-regulation
Atypical_PIKK_ATM_ATM_ST	Q15648	MED1	Q13315	ATM	S1141	G1139E	1139	Missense	proximal	-2	no	16.267	16.890	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	9.540	Up-regulation
Atypical_PIKK_ATM_ATM_ST	Q15648	MED1	Q13315	ATM	S1147	G1154D	1154	Missense	distal	7	no	17.150	17.117	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	9.540	Down-regulation
Atypical_PIKK_ATM_ATM_ST	Q15648	MED1	Q13315	ATM	S1147	S1149F	1149	Missense	proximal	2	no	17.150	15.672	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	9.540	Down-regulation
Atypical_PIKK_ATM_ATM_ST	Q15648	MED1	Q13315	ATM	S1147	S1143C	1143	Missense	distal	-4	no	17.150	15.577	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	9.540	Down-regulation
Atypical_PIKK_ATM_ATM_ST	Q15648	MED1	Q13315	ATM	S1156	G1154D	1154	Missense	proximal	-2	no	10.439	10.584	EPSD	TCGA;ICGC;COSMIC	9.540	Up-regulation
Atypical_PIKK_ATM_ATM_ST	Q15648	MED1	Q13315	ATM	S1156	S1149F	1149	Missense	distal	-7	no	10.439	9.610	EPSD	TCGA;ICGC;COSMIC	9.540	Down-regulation
Atypical_PIKK_ATM_ATM_ST	Q15648	MED1	Q13315	ATM	S1156	S1156F	1156	Missense	central	0	yes	10.439	0.000	EPSD	TCGA;ICGC;COSMIC	9.540	Loss
Atypical_PIKK_ATM_ATM_ST	Q15648	MED1	Q13315	ATM	S1192	H1195Y	1195	Missense	distal	3	no	10.689	10.708	EPSD	TCGA;ICGC;COSMIC	9.540	Up-regulation
Atypical_PIKK_ATM_ATM_ST	Q15648	MED1	Q13315	ATM	S1196	H1195Y	1195	Missense	proximal	-1	no	9.858	10.014	EPSD	TCGA;ICGC;COSMIC	9.540	Up-regulation
Atypical_PIKK_ATM_ATM_ST	Q15648	MED1	Q13315	ATM	S1223	S1227L	1227	Missense	distal	4	no	9.627	9.969	EPSD	TCGA;ICGC;COSMIC	9.540	Up-regulation
Atypical_PIKK_ATM_ATM_ST	Q15648	MED1	Q13315	ATM	S1223	S1218C	1218	Missense	distal	-5	no	9.627	9.720	EPSD	TCGA;ICGC;COSMIC	9.540	Up-regulation
Atypical_PIKK_ATM_ATM_ST	Q15648	MED1	Q13315	ATM	S1417	G1420W	1420	Missense	distal	3	no	10.152	10.399	EPSD	TCGA;ICGC	9.540	Up-regulation
Atypical_PIKK_ATM_ATM_ST	Q15648	MED1	Q13315	ATM	S1465	S1467P	1467	Missense	proximal	2	no	11.512	11.058	EPSD	TCGA;ICGC;COSMIC	9.540	Down-regulation
Atypical_PIKK_ATM_ATM_ST	Q15648	MED1	Q13315	ATM	S1465	G1468D	1468	Missense	distal	3	no	11.512	11.565	EPSD	TCGA;ICGC;COSMIC	9.540	Up-regulation
Atypical_PIKK_ATM_ATM_ST	Q15648	MED1	Q13315	ATM	S1467	S1467P	1467	Missense	central	0	yes	9.794	0.000	EPSD	TCGA;ICGC;COSMIC	9.540	Loss
Atypical_PIKK_ATM_ATM_ST	Q15648	MED1	Q13315	ATM	S1467	G1468D	1468	Missense	proximal	1	no	9.794	10.237	EPSD	TCGA;ICGC;COSMIC	9.540	Up-regulation
Atypical_PIKK_ATM_ATM_ST	Q15648	MED1	Q13315	ATM	S1479	Q1477H	1477	Missense	proximal	-2	no	9.676	9.372	EPSD	TCGA;ICGC;COSMIC	9.540	Loss
Atypical_PIKK_ATM_ATM_ST	Q15648	MED1	Q13315	ATM	S1479	S1475F	1475	Missense	distal	-4	no	9.676	8.277	EPSD	TCGA	9.540	Loss
Atypical_PIKK_ATM_ATM_ST	Q15648	MED1	Q13315	ATM	S1479	D1484V	1484	Missense	distal	5	no	9.676	9.801	EPSD	TCGA;ICGC;COSMIC	9.540	Up-regulation
Atypical_PIKK_ATM_ATM_ST	Q15648	MED1	Q13315	ATM	S1479	D1484N	1484	Missense	distal	5	no	9.676	9.564	EPSD	TCGA;ICGC;COSMIC	9.540	Down-regulation
Atypical_PIKK_ATM_ATM_ST	Q15648	MED1	Q13315	ATM	S1540	M1546V	1546	Missense	distal	6	no	9.538	9.543	EPSD	TCGA;ICGC;COSMIC;GDSC	9.540	Gain
Atypical_PIKK_ATM_ATM_ST	Q15648	MED1	Q13315	ATM	S1561	S1558L	1558	Missense	distal	-3	no	11.373	11.582	EPSD	TCGA;ICGC;COSMIC	9.540	Up-regulation
Atypical_PIKK_ATM_ATM_ST	Q15648	MED1	Q13315	ATM	S1561	A1554S	1554	Missense	distal	-7	no	11.373	11.470	EPSD	TCGA;ICGC;COSMIC	9.540	Up-regulation
Atypical_PIKK_ATM_ATM_ST	Q15648	MED1	Q13315	ATM	S1561	S1561I	1561	Missense	central	0	yes	11.373	0.000	EPSD	TCGA;ICGC	9.540	Loss
Atypical_PIKK_ATM_ATM_ST	P07900	HSP90AA1	Q13315	ATM	T5	P2L	2	Missense	distal	-3	no	12.174	12.187	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	9.540	Up-regulation
Atypical_PIKK_ATM_ATM_ST	P07900	HSP90AA1	Q13315	ATM	T7	P2L	2	Missense	distal	-5	no	12.073	12.092	PhosphoSitePlus;EPSD	TCGA;ICGC;COSMIC	9.540	Up-regulation
Atypical_PIKK_ATM_ATM_ST	Q9BQ15	NABP2	Q13315	ATM	T117	A124V	124	Missense	distal	7	no	12.515	12.533	PhosphoSitePlus	TCGA;ICGC;COSMIC;GDSC	9.540	Up-regulation
Atypical_PIKK_ATM_ATM_ST	Q9BQ15	NABP2	Q13315	ATM	S134	S132L	132	Missense	proximal	-2	no	14.314	13.924	EPSD	TCGA;ICGC;COSMIC	9.540	Down-regulation
Atypical_PIKK_ATM_ATM_ST	Q9BQ15	NABP2	Q13315	ATM	S134	T138A	138	Missense	distal	4	no	14.314	13.879	EPSD	TCGA;ICGC;COSMIC	9.540	Down-regulation
Atypical_PIKK_ATM_ATM_ST	Q9BQ15	NABP2	Q13315	ATM	S134	Q135R	135	Missense	proximal	1	no	14.314	7.662	EPSD	TCGA;ICGC	9.540	Loss
Atypical_PIKK_ATM_ATM_ST	P46527	CDKN1B	Q13315	ATM	S106	A103V	103	Missense	distal	-3	no	13.844	14.708	EPSD	TCGA;ICGC	9.540	Up-regulation
Atypical_PIKK_ATM_ATM_ST	P46527	CDKN1B	Q13315	ATM	S140	E146K	146	Missense	distal	6	no	16.385	16.339	PhosphoSitePlus	TCGA;ICGC;COSMIC	9.540	Down-regulation
Atypical_PIKK_ATM_ATM_ST	P38398	BRCA1	Q13315	ATM	S114	N113K	113	Missense	proximal	-1	no	11.197	11.059	EPSD	TCGA;ICGC;COSMIC	9.540	Down-regulation
Atypical_PIKK_ATM_ATM_ST	P38398	BRCA1	Q13315	ATM	S229	E230Q	230	Missense	proximal	1	no	7.240	13.136	EPSD	TCGA;ICGC;COSMIC	9.540	Gain
Atypical_PIKK_ATM_ATM_ST	P38398	BRCA1	Q13315	ATM	S316	R320T	320	Missense	distal	4	no	14.757	14.663	EPSD	TCGA;COSMIC	9.540	Down-regulation
Atypical_PIKK_ATM_ATM_ST	P38398	BRCA1	Q13315	ATM	S316	W321C	321	Missense	distal	5	no	14.757	14.794	EPSD	TCGA;COSMIC	9.540	Up-regulation
Atypical_PIKK_ATM_ATM_ST	P38398	BRCA1	Q13315	ATM	S316	A314T	314	Missense	proximal	-2	no	14.757	14.857	EPSD	TCGA	9.540	Up-regulation
Atypical_PIKK_ATM_ATM_ST	P38398	BRCA1	Q13315	ATM	S324	R320T	320	Missense	distal	-4	no	10.337	10.765	EPSD	TCGA;COSMIC	9.540	Up-regulation
Atypical_PIKK_ATM_ATM_ST	P38398	BRCA1	Q13315	ATM	S324	W321C	321	Missense	distal	-3	no	10.337	10.194	EPSD	TCGA;COSMIC	9.540	Down-regulation
Atypical_PIKK_ATM_ATM_ST	P38398	BRCA1	Q13315	ATM	S395	E402K	402	Missense	distal	7	no	11.215	11.242	EPSD	TCGA;COSMIC	9.540	Up-regulation
Atypical_PIKK_ATM_ATM_ST	P38398	BRCA1	Q13315	ATM	S449	R446T	446	Missense	distal	-3	no	10.561	9.753	EPSD	TCGA;COSMIC	9.540	Down-regulation
Atypical_PIKK_ATM_ATM_ST	P38398	BRCA1	Q13315	ATM	T528	V525A	525	Missense	distal	-3	no	10.192	9.329	EPSD	TCGA;COSMIC	9.540	Loss
Atypical_PIKK_ATM_ATM_ST	P38398	BRCA1	Q13315	ATM	T528	P529S	529	Missense	proximal	1	no	10.192	3.217	EPSD	TCGA;COSMIC	9.540	Loss
Atypical_PIKK_ATM_ATM_ST	P38398	BRCA1	Q13315	ATM	T528	A524T	524	Missense	distal	-4	no	10.192	10.319	EPSD	TCGA;COSMIC	9.540	Up-regulation
Atypical_PIKK_ATM_ATM_ST	P38398	BRCA1	Q13315	ATM	S694	K690R	690	Missense	distal	-4	no	10.201	10.084	EPSD	TCGA;COSMIC	9.540	Down-regulation
Atypical_PIKK_ATM_ATM_ST	P38398	BRCA1	Q13315	ATM	S694	T688I	688	Missense	distal	-6	no	10.201	9.869	EPSD	TCGA	9.540	Down-regulation
Atypical_PIKK_ATM_ATM_ST	P38398	BRCA1	Q13315	ATM	S753	P747L	747	Missense	distal	-6	no	10.758	10.528	EPSD	TCGA;COSMIC	9.540	Down-regulation
Atypical_PIKK_ATM_ATM_ST	P38398	BRCA1	Q13315	ATM	S896	C903S	903	Missense	distal	7	no	9.789	9.737	EPSD	TCGA;COSMIC	9.540	Down-regulation
Atypical_PIKK_ATM_ATM_ST	P38398	BRCA1	Q13315	ATM	S896	S889C	889	Missense	distal	-7	no	9.789	9.115	EPSD	TCGA;COSMIC	9.540	Loss
Atypical_PIKK_ATM_ATM_ST	P38398	BRCA1	Q13315	ATM	S896	E902K	902	Missense	distal	6	no	9.789	9.743	EPSD	TCGA;COSMIC	9.540	Down-regulation
Atypical_PIKK_ATM_ATM_ST	P38398	BRCA1	Q13315	ATM	S896	V899L	899	Missense	distal	3	no	9.789	9.727	EPSD	TCGA;COSMIC	9.540	Down-regulation
Atypical_PIKK_ATM_ATM_ST	P38398	BRCA1	Q13315	ATM	S896	K893N	893	Missense	distal	-3	no	9.789	9.854	EPSD	TCGA;COSMIC	9.540	Up-regulation
Atypical_PIKK_ATM_ATM_ST	P38398	BRCA1	Q13315	ATM	S956	Q957E	957	Missense	proximal	1	no	13.238	7.342	EPSD	TCGA;COSMIC	9.540	Loss
Atypical_PIKK_ATM_ATM_ST	P38398	BRCA1	Q13315	ATM	S956	E962A	962	Missense	distal	6	no	13.238	13.220	EPSD	TCGA;COSMIC	9.540	Down-regulation
Atypical_PIKK_ATM_ATM_ST	P38398	BRCA1	Q13315	ATM	S1009	E1013Q	1013	Missense	distal	4	no	11.428	11.760	EPSD	TCGA	9.540	Up-regulation
Atypical_PIKK_ATM_ATM_ST	P38398	BRCA1	Q13315	ATM	S1009	N1002K	1002	Missense	distal	-7	no	11.428	11.302	EPSD	TCGA	9.540	Down-regulation
Atypical_PIKK_ATM_ATM_ST	P38398	BRCA1	Q13315	ATM	S1143	H1141R	1141	Missense	proximal	-2	no	15.311	15.296	EPSD	TCGA	9.540	Down-regulation
Atypical_PIKK_ATM_ATM_ST	P38398	BRCA1	Q13315	ATM	S1212	E1210Q	1210	Missense	proximal	-2	no	9.588	9.283	EPSD	TCGA;COSMIC	9.540	Loss
Atypical_PIKK_ATM_ATM_ST	P38398	BRCA1	Q13315	ATM	S1212	E1214D	1214	Missense	proximal	2	no	9.588	9.457	EPSD	TCGA;COSMIC	9.540	Loss
Atypical_PIKK_ATM_ATM_ST	P38398	BRCA1	Q13315	ATM	S1212	S1211F	1211	Missense	proximal	-1	no	9.588	9.161	EPSD	TCGA;COSMIC	9.540	Loss
Atypical_PIKK_ATM_ATM_ST	P38398	BRCA1	Q13315	ATM	S1212	K1207N	1207	Missense	distal	-5	no	9.588	9.643	EPSD	TCGA;COSMIC	9.540	Up-regulation
Atypical_PIKK_ATM_ATM_ST	P38398	BRCA1	Q13315	ATM	S1212	L1216V	1216	Missense	distal	4	no	9.588	9.552	EPSD	TCGA;COSMIC	9.540	Down-regulation
Atypical_PIKK_ATM_ATM_ST	P38398	BRCA1	Q13315	ATM	S1218	E1214D	1214	Missense	distal	-4	no	10.333	10.050	EPSD	TCGA;COSMIC	9.540	Down-regulation
Atypical_PIKK_ATM_ATM_ST	P38398	BRCA1	Q13315	ATM	S1218	S1211F	1211	Missense	distal	-7	no	10.333	9.504	EPSD	TCGA;COSMIC	9.540	Loss
Atypical_PIKK_ATM_ATM_ST	P38398	BRCA1	Q13315	ATM	S1218	L1216V	1216	Missense	proximal	-2	no	10.333	10.058	EPSD	TCGA;COSMIC	9.540	Down-regulation
Atypical_PIKK_ATM_ATM_ST	P38398	BRCA1	Q13315	ATM	S1239	T1242A	1242	Missense	distal	3	no	11.480	11.455	EPSD	TCGA;COSMIC	9.540	Down-regulation
Atypical_PIKK_ATM_ATM_ST	P38398	BRCA1	Q13315	ATM	S1239	H1244N	1244	Missense	distal	5	no	11.480	11.315	EPSD	TCGA;COSMIC	9.540	Down-regulation
Atypical_PIKK_ATM_ATM_ST	P38398	BRCA1	Q13315	ATM	T1312	I1318T	1318	Missense	distal	6	no	12.945	12.976	EPSD	TCGA;COSMIC	9.540	Up-regulation
Atypical_PIKK_ATM_ATM_ST	P38398	BRCA1	Q13315	ATM	T1312	N1309I	1309	Missense	distal	-3	no	12.945	13.642	EPSD	TCGA;COSMIC	9.540	Up-regulation
Atypical_PIKK_ATM_ATM_ST	P38398	BRCA1	Q13315	ATM	T1312	N1309H	1309	Missense	distal	-3	no	12.945	13.067	EPSD	TCGA;COSMIC	9.540	Up-regulation
Atypical_PIKK_ATM_ATM_ST	P38398	BRCA1	Q13315	ATM	T1312	T1310I	1310	Missense	proximal	-2	no	12.945	12.344	EPSD	TCGA;COSMIC	9.540	Down-regulation
Atypical_PIKK_ATM_ATM_ST	P38398	BRCA1	Q13315	ATM	T1312	P1315L	1315	Missense	distal	3	no	12.945	13.076	EPSD	TCGA;COSMIC	9.540	Up-regulation
Atypical_PIKK_ATM_ATM_ST	P38398	BRCA1	Q13315	ATM	T1394	T1399S	1399	Missense	distal	5	no	13.113	13.130	EPSD	TCGA;COSMIC	9.540	Up-regulation
Atypical_PIKK_ATM_ATM_ST	P38398	BRCA1	Q13315	ATM	T1394	R1397M	1397	Missense	distal	3	no	13.113	13.184	EPSD	TCGA;COSMIC	9.540	Up-regulation
Atypical_PIKK_ATM_ATM_ST	P38398	BRCA1	Q13315	ATM	S1423	E1419K	1419	Missense	distal	-4	no	14.237	13.265	EPSD;PhosphoSitePlus	TCGA;COSMIC	9.540	Down-regulation
Atypical_PIKK_ATM_ATM_ST	P38398	BRCA1	Q13315	ATM	S1423	G1422V	1422	Missense	proximal	-1	no	14.237	14.006	EPSD;PhosphoSitePlus	TCGA;COSMIC	9.540	Down-regulation
Atypical_PIKK_ATM_ATM_ST	P38398	BRCA1	Q13315	ATM	S1486	G1492R	1492	Missense	distal	6	no	10.008	10.009	EPSD	TCGA;COSMIC	9.540	Up-regulation
Atypical_PIKK_ATM_ATM_ST	P38398	BRCA1	Q13315	ATM	S1497	G1492R	1492	Missense	distal	-5	no	12.560	12.581	EPSD;PhosphoSitePlus	TCGA;COSMIC	9.540	Up-regulation
Atypical_PIKK_ATM_ATM_ST	Q96KQ7	EHMT2	Q13315	ATM	S47	R46C	46	Missense	proximal	-1	no	9.441	9.616	EPSD	TCGA;COSMIC	9.540	Gain
Atypical_PIKK_ATM_ATM_ST	Q96KQ7	EHMT2	Q13315	ATM	S47	R46H	46	Missense	proximal	-1	no	9.441	9.611	EPSD	TCGA	9.540	Gain
Atypical_PIKK_ATM_ATM_ST	Q96KQ7	EHMT2	Q13315	ATM	S47	L41S	41	Missense	distal	-6	no	9.441	9.729	EPSD	TCGA	9.540	Gain
Atypical_PIKK_ATM_ATM_ST	Q96KQ7	EHMT2	Q13315	ATM	S119	P117L	117	Missense	proximal	-2	no	11.251	11.098	EPSD	TCGA;COSMIC	9.540	Down-regulation
Atypical_PIKK_ATM_ATM_ST	Q96KQ7	EHMT2	Q13315	ATM	S246	S246L	246	Missense	central	0	yes	9.608	0.000	EPSD	TCGA;COSMIC	9.540	Loss
Atypical_PIKK_ATM_ATM_ST	Q96KQ7	EHMT2	Q13315	ATM	S246	R245C	245	Missense	proximal	-1	no	9.608	9.783	EPSD	TCGA;COSMIC	9.540	Up-regulation
Atypical_PIKK_ATM_ATM_ST	Q96KQ7	EHMT2	Q13315	ATM	S246	T252M	252	Missense	distal	6	no	9.608	9.589	EPSD	TCGA	9.540	Down-regulation
Atypical_PIKK_ATM_ATM_ST	Q96KQ7	EHMT2	Q13315	ATM	S246	T250I	250	Missense	distal	4	no	9.608	10.183	EPSD	TCGA	9.540	Up-regulation
Atypical_PIKK_ATM_ATM_ST	Q96KQ7	EHMT2	Q13315	ATM	T250	S246L	246	Missense	distal	-4	no	9.997	9.057	EPSD	TCGA;COSMIC	9.540	Loss
Atypical_PIKK_ATM_ATM_ST	Q96KQ7	EHMT2	Q13315	ATM	T250	R245C	245	Missense	distal	-5	no	9.997	10.014	EPSD	TCGA;COSMIC	9.540	Up-regulation
Atypical_PIKK_ATM_ATM_ST	Q96KQ7	EHMT2	Q13315	ATM	T250	T252M	252	Missense	proximal	2	no	9.997	9.202	EPSD	TCGA	9.540	Loss
Atypical_PIKK_ATM_ATM_ST	Q96KQ7	EHMT2	Q13315	ATM	T250	T250I	250	Missense	central	0	yes	9.997	0.000	EPSD	TCGA	9.540	Loss
Atypical_PIKK_ATM_ATM_ST	Q96KQ7	EHMT2	Q13315	ATM	S379	S379L	379	Missense	central	0	yes	10.766	0.000	EPSD	TCGA;COSMIC	9.540	Loss
Atypical_PIKK_ATM_ATM_ST	Q96KQ7	EHMT2	Q13315	ATM	S379	G375D	375	Missense	distal	-4	no	10.766	11.550	EPSD	TCGA;COSMIC	9.540	Up-regulation
Atypical_PIKK_ATM_ATM_ST	Q96KQ7	EHMT2	Q13315	ATM	S391	P395S	395	Missense	distal	4	no	9.865	9.743	EPSD	TCGA;COSMIC	9.540	Down-regulation
Atypical_PIKK_ATM_ATM_ST	Q96KQ7	EHMT2	Q13315	ATM	S391	G398E	398	Missense	distal	7	no	9.865	9.820	EPSD	TCGA;COSMIC	9.540	Down-regulation
Atypical_PIKK_ATM_ATM_ST	Q96KQ7	EHMT2	Q13315	ATM	S401	P395S	395	Missense	distal	-6	no	10.053	10.112	EPSD	TCGA;COSMIC	9.540	Up-regulation
Atypical_PIKK_ATM_ATM_ST	Q96KQ7	EHMT2	Q13315	ATM	S401	G398E	398	Missense	distal	-3	no	10.053	9.615	EPSD	TCGA;COSMIC	9.540	Down-regulation
Atypical_PIKK_ATM_ATM_ST	Q96KQ7	EHMT2	Q13315	ATM	S569	P563A	563	Missense	distal	-6	no	16.412	16.451	PhosphoSitePlus	TCGA	9.540	Up-regulation
Atypical_PIKK_ATM_ATM_ST	Q96KQ7	EHMT2	Q13315	ATM	S569	P563S	563	Missense	distal	-6	no	16.412	16.471	PhosphoSitePlus	TCGA;COSMIC	9.540	Up-regulation
Atypical_PIKK_ATM_ATM_ST	Q96KQ7	EHMT2	Q13315	ATM	S1204	E1201Q	1201	Missense	distal	-3	no	9.431	9.555	EPSD	TCGA;COSMIC	9.540	Gain
Atypical_PIKK_ATM_ATM_ST	Q96KQ7	EHMT2	Q13315	ATM	S1204	G1203S	1203	Missense	proximal	-1	no	9.431	9.623	EPSD	TCGA;COSMIC	9.540	Gain
Atypical_PIKK_ATM_ATM_ST	P23919	DTYMK	Q13315	ATM	S88	P81L	81	Missense	distal	-7	no	12.473	12.121	PhosphoSitePlus	TCGA;ICGC;GDSC;CCLE	9.540	Down-regulation
Atypical_PIKK_ATM_ATM_ST	Q99708	RBBP8	Q13315	ATM	T271	E267K	267	Missense	distal	-4	no	15.474	14.502	EPSD	TCGA;ICGC;COSMIC	9.540	Down-regulation
Atypical_PIKK_ATM_ATM_ST	Q99708	RBBP8	Q13315	ATM	T271	M275L	275	Missense	distal	4	no	15.474	15.555	EPSD	TCGA;ICGC;COSMIC	9.540	Up-regulation
Atypical_PIKK_ATM_ATM_ST	Q99708	RBBP8	Q13315	ATM	T271	P274L	274	Missense	distal	3	no	15.474	15.604	EPSD	TCGA;ICGC;COSMIC	9.540	Up-regulation
Atypical_PIKK_ATM_ATM_ST	Q99708	RBBP8	Q13315	ATM	S276	M275L	275	Missense	proximal	-1	no	10.302	10.458	EPSD	TCGA;ICGC;COSMIC	9.540	Up-regulation
Atypical_PIKK_ATM_ATM_ST	Q99708	RBBP8	Q13315	ATM	S276	P274L	274	Missense	proximal	-2	no	10.302	10.149	EPSD	TCGA;ICGC;COSMIC	9.540	Down-regulation
Atypical_PIKK_ATM_ATM_ST	Q99708	RBBP8	Q13315	ATM	S327	A332T	332	Missense	distal	5	no	10.777	10.712	EPSD	TCGA;ICGC;COSMIC	9.540	Down-regulation
Atypical_PIKK_ATM_ATM_ST	Q99708	RBBP8	Q13315	ATM	S379	S379F	379	Missense	central	0	yes	10.725	0.000	EPSD	TCGA;ICGC;COSMIC	9.540	Loss
Atypical_PIKK_ATM_ATM_ST	Q99708	RBBP8	Q13315	ATM	S539	R536C	536	Missense	distal	-3	no	10.074	9.502	EPSD	TCGA;ICGC	9.540	Loss
Atypical_PIKK_ATM_ATM_ST	Q99708	RBBP8	Q13315	ATM	S539	S533F	533	Missense	distal	-6	no	10.074	9.543	EPSD	TCGA;ICGC;COSMIC	9.540	Down-regulation
Atypical_PIKK_ATM_ATM_ST	Q99708	RBBP8	Q13315	ATM	S555	E557V	557	Missense	proximal	2	no	16.693	15.290	EPSD	TCGA;ICGC;COSMIC	9.540	Down-regulation
Atypical_PIKK_ATM_ATM_ST	Q99708	RBBP8	Q13315	ATM	S568	P569T	569	Missense	proximal	1	no	11.175	6.168	EPSD	TCGA;ICGC;COSMIC	9.540	Loss
Atypical_PIKK_ATM_ATM_ST	Q99708	RBBP8	Q13315	ATM	S568	C567W	567	Missense	proximal	-1	no	11.175	10.996	EPSD	TCGA;ICGC;COSMIC	9.540	Down-regulation
Atypical_PIKK_ATM_ATM_ST	Q99708	RBBP8	Q13315	ATM	S664	V670I	670	Missense	distal	6	no	13.382	13.365	EPSD;PhosphoSitePlus	TCGA;ICGC	9.540	Down-regulation
Atypical_PIKK_ATM_ATM_ST	Q99708	RBBP8	Q13315	ATM	S664	D658Y	658	Missense	distal	-6	no	13.382	13.160	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	9.540	Down-regulation
Atypical_PIKK_ATM_ATM_ST	Q99708	RBBP8	Q13315	ATM	S723	K719Q	719	Missense	distal	-4	no	10.530	10.779	EPSD	TCGA;COSMIC	9.540	Up-regulation
Atypical_PIKK_ATM_ATM_ST	Q99708	RBBP8	Q13315	ATM	S745	E751Q	751	Missense	distal	6	no	14.380	14.333	PhosphoSitePlus;EPSD	TCGA;COSMIC	9.540	Down-regulation
Atypical_PIKK_ATM_ATM_ST	Q99708	RBBP8	Q13315	ATM	S745	E752Q	752	Missense	distal	7	no	14.380	14.394	PhosphoSitePlus;EPSD	TCGA;COSMIC;GDSC;CCLE	9.540	Up-regulation
Atypical_PIKK_ATM_ATM_ST	Q99708	RBBP8	Q13315	ATM	S789	H795D	795	Missense	distal	6	no	9.823	9.834	EPSD	TCGA;ICGC;COSMIC	9.540	Up-regulation
Atypical_PIKK_ATM_ATM_ST	Q99708	RBBP8	Q13315	ATM	T847	V854A	854	Missense	distal	7	no	12.166	12.148	EPSD	TCGA;ICGC;COSMIC	9.540	Down-regulation
Atypical_PIKK_ATM_ATM_ST	Q99708	RBBP8	Q13315	ATM	T847	R841C	841	Missense	distal	-6	no	12.166	11.966	EPSD	TCGA;ICGC;COSMIC	9.540	Down-regulation
Atypical_PIKK_ATM_ATM_ST	Q99708	RBBP8	Q13315	ATM	T859	V854A	854	Missense	distal	-5	no	13.405	13.284	EPSD	TCGA;ICGC;COSMIC	9.540	Down-regulation
Atypical_PIKK_ATM_ATM_ST	Q99708	RBBP8	Q13315	ATM	T859	E864K	864	Missense	distal	5	no	13.405	13.580	EPSD	TCGA;COSMIC	9.540	Up-regulation
Atypical_PIKK_ATM_ATM_ST	Q99708	RBBP8	Q13315	ATM	T859	M863L	863	Missense	distal	4	no	13.405	13.486	EPSD	TCGA;ICGC;COSMIC	9.540	Up-regulation
Atypical_PIKK_ATM_ATM_ST	Q99708	RBBP8	Q13315	ATM	T859	M863I	863	Missense	distal	4	no	13.405	13.807	EPSD	TCGA;COSMIC	9.540	Up-regulation
Atypical_PIKK_ATM_ATM_ST	O75150	RNF40	Q13315	ATM	S114	S119F	119	Missense	distal	5	no	14.381	14.687	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	9.540	Up-regulation
Atypical_PIKK_ATM_ATM_ST	O75150	RNF40	Q13315	ATM	S114	A121E	121	Missense	distal	7	no	14.381	14.346	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	9.540	Down-regulation
Atypical_PIKK_ATM_ATM_ST	O75150	RNF40	Q13315	ATM	S114	R110Q	110	Missense	distal	-4	no	14.381	14.746	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	9.540	Up-regulation
Atypical_PIKK_ATM_ATM_ST	O75150	RNF40	Q13315	ATM	S114	E113D	113	Missense	proximal	-1	no	14.381	14.116	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	9.540	Down-regulation
Atypical_PIKK_ATM_ATM_ST	O75150	RNF40	Q13315	ATM	S114	R110L	110	Missense	distal	-4	no	14.381	14.252	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	9.540	Down-regulation
Atypical_PIKK_ATM_ATM_ST	O75150	RNF40	Q13315	ATM	S114	A107V	107	Missense	distal	-7	no	14.381	13.997	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	9.540	Down-regulation
Atypical_PIKK_ATM_ATM_ST	O75150	RNF40	Q13315	ATM	T127	A121E	121	Missense	distal	-6	no	13.562	13.770	EPSD	TCGA;ICGC;COSMIC	9.540	Up-regulation
Atypical_PIKK_ATM_ATM_ST	O75150	RNF40	Q13315	ATM	T127	A124G	124	Missense	distal	-3	no	13.562	14.286	EPSD	TCGA;ICGC;COSMIC	9.540	Up-regulation
Atypical_PIKK_ATM_ATM_ST	O75150	RNF40	Q13315	ATM	S219	A225T	225	Missense	distal	6	no	10.983	10.967	EPSD	TCGA;ICGC	9.540	Down-regulation
Atypical_PIKK_ATM_ATM_ST	O75150	RNF40	Q13315	ATM	S819	G816V	816	Missense	distal	-3	no	14.389	14.529	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	9.540	Up-regulation
Atypical_PIKK_ATM_ATM_ST	O75150	RNF40	Q13315	ATM	S819	L825P	825	Missense	distal	6	no	14.389	14.435	EPSD;PhosphoSitePlus	TCGA;ICGC	9.540	Up-regulation
Atypical_PIKK_ATM_ATM_ST	O75150	RNF40	Q13315	ATM	S853	R852H	852	Missense	proximal	-1	no	13.618	13.788	PhosphoSitePlus;EPSD	TCGA;ICGC;COSMIC	9.540	Up-regulation
Atypical_PIKK_ATM_ATM_ST	Q5VTR2	RNF20	Q13315	ATM	S28	T31A	31	Missense	distal	3	no	9.751	9.726	EPSD	TCGA;ICGC;COSMIC;CCLE	9.540	Down-regulation
Atypical_PIKK_ATM_ATM_ST	Q5VTR2	RNF20	Q13315	ATM	S28	E33G	33	Missense	distal	5	no	9.751	10.100	EPSD	TCGA;ICGC;COSMIC	9.540	Up-regulation
Atypical_PIKK_ATM_ATM_ST	Q5VTR2	RNF20	Q13315	ATM	T85	S89L	89	Missense	distal	4	no	10.867	11.209	EPSD	TCGA;ICGC;COSMIC	9.540	Up-regulation
Atypical_PIKK_ATM_ATM_ST	Q5VTR2	RNF20	Q13315	ATM	T85	R81Q	81	Missense	distal	-4	no	10.867	11.233	EPSD	TCGA;ICGC;COSMIC	9.540	Up-regulation
Atypical_PIKK_ATM_ATM_ST	Q5VTR2	RNF20	Q13315	ATM	T85	I92T	92	Missense	distal	7	no	10.867	10.853	EPSD	TCGA;ICGC;COSMIC	9.540	Down-regulation
Atypical_PIKK_ATM_ATM_ST	Q5VTR2	RNF20	Q13315	ATM	S172	R177L	177	Missense	distal	5	no	14.364	14.363	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	9.540	Down-regulation
Atypical_PIKK_ATM_ATM_ST	Q5VTR2	RNF20	Q13315	ATM	S172	E179K	179	Missense	distal	7	no	14.364	14.391	EPSD;PhosphoSitePlus	TCGA;ICGC;CCLE	9.540	Up-regulation
Atypical_PIKK_ATM_ATM_ST	Q5VTR2	RNF20	Q13315	ATM	S262	T259I	259	Missense	distal	-3	no	10.393	11.131	EPSD	TCGA;ICGC;COSMIC	9.540	Up-regulation
Atypical_PIKK_ATM_ATM_ST	Q5VTR2	RNF20	Q13315	ATM	S262	E261K	261	Missense	proximal	-1	no	10.393	9.990	EPSD	TCGA;ICGC;COSMIC	9.540	Down-regulation
Atypical_PIKK_ATM_ATM_ST	Q5VTR2	RNF20	Q13315	ATM	S522	D528Y	528	Missense	distal	6	no	15.545	15.526	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	9.540	Down-regulation
Atypical_PIKK_ATM_ATM_ST	Q5VTR2	RNF20	Q13315	ATM	S522	S522F	522	Missense	central	0	yes	15.545	0.000	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	9.540	Loss
Atypical_PIKK_ATM_ATM_ST	Q5VTR2	RNF20	Q13315	ATM	S522	S525N	525	Missense	distal	3	no	15.545	15.745	EPSD;PhosphoSitePlus	TCGA;ICGC	9.540	Up-regulation
Atypical_PIKK_ATM_ATM_ST	Q5VTR2	RNF20	Q13315	ATM	S540	E541K	541	Missense	proximal	1	no	9.612	8.661	EPSD	TCGA;ICGC;COSMIC	9.540	Loss
Atypical_PIKK_ATM_ATM_ST	Q5VTR2	RNF20	Q13315	ATM	S540	P533H	533	Missense	distal	-7	no	9.612	9.535	EPSD	TCGA;ICGC	9.540	Loss
Atypical_PIKK_ATM_ATM_ST	Q5VTR2	RNF20	Q13315	ATM	S545	E541K	541	Missense	distal	-4	no	16.618	15.646	PhosphoSitePlus;EPSD	TCGA;ICGC;COSMIC	9.540	Down-regulation
Atypical_PIKK_ATM_ATM_ST	Q5VTR2	RNF20	Q13315	ATM	S545	A549T	549	Missense	distal	4	no	16.618	17.053	PhosphoSitePlus;EPSD	TCGA;ICGC;COSMIC	9.540	Up-regulation
Atypical_PIKK_ATM_ATM_ST	Q5VTR2	RNF20	Q13315	ATM	S553	N558S	558	Missense	distal	5	no	14.520	14.545	EPSD	TCGA;ICGC;COSMIC	9.540	Up-regulation
Atypical_PIKK_ATM_ATM_ST	Q5VTR2	RNF20	Q13315	ATM	S553	A549T	549	Missense	distal	-4	no	14.520	14.647	EPSD	TCGA;ICGC;COSMIC	9.540	Up-regulation
Atypical_PIKK_ATM_ATM_ST	P14618	PKM	Q13315	ATM	T15	F12Y	12	Missense	distal	-3	no	15.755	14.816	EPSD	TCGA;ICGC;COSMIC	9.540	Down-regulation
Atypical_PIKK_ATM_ATM_ST	O15355	PPM1G	Q13315	ATM	S183	A190V	190	Missense	distal	7	no	14.208	14.226	PhosphoSitePlus	TCGA;ICGC;COSMIC	9.540	Up-regulation
Atypical_PIKK_ATM_ATM_ST	O15355	PPM1G	Q13315	ATM	S183	G188W	188	Missense	distal	5	no	14.208	14.219	PhosphoSitePlus	TCGA;ICGC;COSMIC	9.540	Up-regulation
Atypical_PIKK_ATM_ATM_ST	O15355	PPM1G	Q13315	ATM	S201	E198D	198	Missense	distal	-3	no	14.556	14.961	EPSD	TCGA;ICGC;COSMIC	9.540	Up-regulation
Atypical_PIKK_ATM_ATM_ST	O15355	PPM1G	Q13315	ATM	S201	P206L	206	Missense	distal	5	no	14.556	14.539	EPSD	TCGA;ICGC;COSMIC	9.540	Down-regulation
Atypical_PIKK_ATM_ATM_ST	O15355	PPM1G	Q13315	ATM	S201	G205V	205	Missense	distal	4	no	14.556	14.733	EPSD	TCGA;ICGC	9.540	Up-regulation
Atypical_PIKK_ATM_ATM_ST	O15355	PPM1G	Q13315	ATM	S325	S327R	327	Missense	proximal	2	no	9.571	8.573	EPSD	TCGA;ICGC;COSMIC	9.540	Loss
Atypical_PIKK_ATM_ATM_ST	Q14839	CHD4	Q13315	ATM	S145	K146E	146	Missense	proximal	1	no	10.016	10.968	EPSD	TCGA;COSMIC	9.540	Up-regulation
Atypical_PIKK_ATM_ATM_ST	Q14839	CHD4	Q13315	ATM	S145	D141E	141	Missense	distal	-4	no	10.016	10.299	EPSD	TCGA;COSMIC	9.540	Up-regulation
Atypical_PIKK_ATM_ATM_ST	Q14839	CHD4	Q13315	ATM	S151	K146E	146	Missense	distal	-5	no	11.030	10.948	EPSD	TCGA;COSMIC	9.540	Down-regulation
Atypical_PIKK_ATM_ATM_ST	Q14839	CHD4	Q13315	ATM	S168	E170G	170	Missense	proximal	2	no	9.655	8.286	EPSD	TCGA;COSMIC	9.540	Loss
Atypical_PIKK_ATM_ATM_ST	Q14839	CHD4	Q13315	ATM	S168	D171A	171	Missense	distal	3	no	9.655	9.527	EPSD	TCGA;COSMIC	9.540	Loss
Atypical_PIKK_ATM_ATM_ST	Q14839	CHD4	Q13315	ATM	S168	H165L	165	Missense	distal	-3	no	9.655	9.769	EPSD	TCGA;COSMIC	9.540	Up-regulation
Atypical_PIKK_ATM_ATM_ST	Q14839	CHD4	Q13315	ATM	S182	N177D	177	Missense	distal	-5	no	12.750	12.567	EPSD	TCGA;COSMIC	9.540	Down-regulation
Atypical_PIKK_ATM_ATM_ST	Q14839	CHD4	Q13315	ATM	S310	R305H	305	Missense	distal	-5	no	11.814	11.786	EPSD	TCGA;COSMIC	9.540	Down-regulation
Atypical_PIKK_ATM_ATM_ST	Q14839	CHD4	Q13315	ATM	S310	R305C	305	Missense	distal	-5	no	11.814	11.831	EPSD	TCGA;COSMIC	9.540	Up-regulation
Atypical_PIKK_ATM_ATM_ST	Q14839	CHD4	Q13315	ATM	S515	W508R	508	Missense	distal	-7	no	11.502	11.692	EPSD	TCGA;COSMIC	9.540	Up-regulation
Atypical_PIKK_ATM_ATM_ST	Q14839	CHD4	Q13315	ATM	S515	P520H	520	Missense	distal	5	no	11.502	11.460	EPSD	TCGA;COSMIC	9.540	Down-regulation
Atypical_PIKK_ATM_ATM_ST	Q14839	CHD4	Q13315	ATM	S515	R521Q	521	Missense	distal	6	no	11.502	11.498	EPSD	TCGA;COSMIC	9.540	Down-regulation
Atypical_PIKK_ATM_ATM_ST	Q14839	CHD4	Q13315	ATM	S515	P520S	520	Missense	distal	5	no	11.502	11.320	EPSD	TCGA;COSMIC	9.540	Down-regulation
Atypical_PIKK_ATM_ATM_ST	Q14839	CHD4	Q13315	ATM	S851	S851F	851	Missense	central	0	yes	10.306	0.000	EPSD	TCGA;COSMIC	9.540	Loss
Atypical_PIKK_ATM_ATM_ST	Q14839	CHD4	Q13315	ATM	T991	R992Q	992	Missense	proximal	1	no	4.154	10.805	EPSD	TCGA;COSMIC	9.540	Gain
Atypical_PIKK_ATM_ATM_ST	Q14839	CHD4	Q13315	ATM	S1073	R1068H	1068	Missense	distal	-5	no	12.906	12.878	EPSD	TCGA;COSMIC;GDSC	9.540	Down-regulation
Atypical_PIKK_ATM_ATM_ST	Q14839	CHD4	Q13315	ATM	S1073	R1068C	1068	Missense	distal	-5	no	12.906	12.923	EPSD	TCGA;COSMIC;GDSC;CCLE	9.540	Up-regulation
Atypical_PIKK_ATM_ATM_ST	Q14839	CHD4	Q13315	ATM	T1207	R1200Q	1200	Missense	distal	-7	no	9.350	9.550	EPSD	TCGA;COSMIC	9.540	Gain
Atypical_PIKK_ATM_ATM_ST	Q14839	CHD4	Q13315	ATM	S1370	E1371Q	1371	Missense	proximal	1	no	9.342	15.239	EPSD	TCGA;COSMIC	9.540	Gain
Atypical_PIKK_ATM_ATM_ST	Q14839	CHD4	Q13315	ATM	S1370	V1368M	1368	Missense	proximal	-2	no	9.342	9.569	EPSD	TCGA;COSMIC	9.540	Gain
Atypical_PIKK_ATM_ATM_ST	Q14839	CHD4	Q13315	ATM	S1531	P1533L	1533	Missense	proximal	2	no	13.042	12.253	EPSD	TCGA;COSMIC	9.540	Down-regulation
Atypical_PIKK_ATM_ATM_ST	Q14839	CHD4	Q13315	ATM	S1531	N1527K	1527	Missense	distal	-4	no	13.042	13.277	EPSD	TCGA;COSMIC	9.540	Up-regulation
Atypical_PIKK_ATM_ATM_ST	Q14839	CHD4	Q13315	ATM	S1531	S1535L	1535	Missense	distal	4	no	13.042	13.384	EPSD	TCGA;COSMIC	9.540	Up-regulation
Atypical_PIKK_ATM_ATM_ST	Q14839	CHD4	Q13315	ATM	S1531	P1533T	1533	Missense	proximal	2	no	13.042	13.235	EPSD	TCGA	9.540	Up-regulation
Atypical_PIKK_ATM_ATM_ST	Q14839	CHD4	Q13315	ATM	S1531	M1530I	1530	Missense	proximal	-1	no	13.042	13.112	EPSD	TCGA;COSMIC	9.540	Up-regulation
Atypical_PIKK_ATM_ATM_ST	Q14839	CHD4	Q13315	ATM	S1535	P1541A	1541	Missense	distal	6	no	10.548	10.565	EPSD	TCGA;COSMIC	9.540	Up-regulation
Atypical_PIKK_ATM_ATM_ST	Q14839	CHD4	Q13315	ATM	S1535	P1533L	1533	Missense	proximal	-2	no	10.548	10.395	EPSD	TCGA;COSMIC	9.540	Down-regulation
Atypical_PIKK_ATM_ATM_ST	Q14839	CHD4	Q13315	ATM	S1535	S1535L	1535	Missense	central	0	yes	10.548	0.000	EPSD	TCGA;COSMIC	9.540	Loss
Atypical_PIKK_ATM_ATM_ST	Q14839	CHD4	Q13315	ATM	S1535	K1539E	1539	Missense	distal	4	no	10.548	10.170	EPSD	TCGA;COSMIC	9.540	Down-regulation
Atypical_PIKK_ATM_ATM_ST	Q14839	CHD4	Q13315	ATM	S1535	P1533T	1533	Missense	proximal	-2	no	10.548	10.697	EPSD	TCGA	9.540	Up-regulation
Atypical_PIKK_ATM_ATM_ST	Q14839	CHD4	Q13315	ATM	S1535	M1530I	1530	Missense	distal	-5	no	10.548	10.578	EPSD	TCGA;COSMIC	9.540	Up-regulation
Atypical_PIKK_ATM_ATM_ST	Q14839	CHD4	Q13315	ATM	S1535	P1541L	1541	Missense	distal	6	no	10.548	10.502	EPSD	TCGA;COSMIC	9.540	Down-regulation
Atypical_PIKK_ATM_ATM_ST	Q14839	CHD4	Q13315	ATM	S1537	K1539E	1539	Missense	proximal	2	no	8.240	9.571	EPSD	TCGA;COSMIC	9.540	Gain
Atypical_PIKK_ATM_ATM_ST	Q14839	CHD4	Q13315	ATM	T1549	P1543L	1543	Missense	distal	-6	no	12.464	12.235	EPSD	TCGA;COSMIC	9.540	Down-regulation
Atypical_PIKK_ATM_ATM_ST	Q14839	CHD4	Q13315	ATM	T1595	S1602L	1602	Missense	distal	7	no	12.304	12.323	EPSD	TCGA;COSMIC;GDSC;CCLE	9.540	Up-regulation
Atypical_PIKK_ATM_ATM_ST	Q14839	CHD4	Q13315	ATM	T1595	S1602P	1602	Missense	distal	7	no	12.304	12.322	EPSD	TCGA;COSMIC;GDSC	9.540	Up-regulation
Atypical_PIKK_ATM_ATM_ST	Q14839	CHD4	Q13315	ATM	T1725	R1732L	1732	Missense	distal	7	no	10.136	10.121	EPSD	TCGA;COSMIC	9.540	Down-regulation
Atypical_PIKK_ATM_ATM_ST	Q14839	CHD4	Q13315	ATM	T1725	R1732W	1732	Missense	distal	7	no	10.136	10.162	EPSD	TCGA;COSMIC	9.540	Up-regulation
Atypical_PIKK_ATM_ATM_ST	Q14839	CHD4	Q13315	ATM	T1904	E1902K	1902	Missense	proximal	-2	no	9.590	9.015	EPSD	TCGA;COSMIC	9.540	Loss
Atypical_PIKK_ATM_ATM_ST	Q9NQS1	AVEN	Q13315	ATM	S110	R112I	112	Missense	proximal	2	no	9.271	9.584	EPSD	TCGA;ICGC	9.540	Gain
Atypical_PIKK_ATM_ATM_ST	Q9NQS1	AVEN	Q13315	ATM	S135	V128F	128	Missense	distal	-7	no	13.656	13.307	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	9.540	Down-regulation
Atypical_PIKK_ATM_ATM_ST	Q9NQS1	AVEN	Q13315	ATM	S135	E131Q	131	Missense	distal	-4	no	13.656	12.933	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	9.540	Down-regulation
Atypical_PIKK_ATM_ATM_ST	Q9NQS1	AVEN	Q13315	ATM	S135	N129S	129	Missense	distal	-6	no	13.656	13.772	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	9.540	Up-regulation
Atypical_PIKK_ATM_ATM_ST	Q9NQS1	AVEN	Q13315	ATM	S135	S135L	135	Missense	central	0	yes	13.656	0.000	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	9.540	Loss
Atypical_PIKK_ATM_ATM_ST	Q9NQS1	AVEN	Q13315	ATM	S135	D140Y	140	Missense	distal	5	no	13.656	13.634	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	9.540	Down-regulation
Atypical_PIKK_ATM_ATM_ST	Q9NQS1	AVEN	Q13315	ATM	S268	D267A	267	Missense	proximal	-1	no	12.284	12.177	EPSD	TCGA;ICGC;COSMIC	9.540	Down-regulation
Atypical_PIKK_ATM_ATM_ST	Q9NQS1	AVEN	Q13315	ATM	S268	S273F	273	Missense	distal	5	no	12.284	12.590	EPSD	TCGA;ICGC;COSMIC	9.540	Up-regulation
Atypical_PIKK_ATM_ATM_ST	Q9NQS1	AVEN	Q13315	ATM	S268	S268Y	268	Missense	central	0	yes	12.284	0.000	EPSD	TCGA;ICGC;COSMIC	9.540	Loss
Atypical_PIKK_ATM_ATM_ST	Q9NQS1	AVEN	Q13315	ATM	S308	T307M	307	Missense	proximal	-1	no	14.642	14.341	PhosphoSitePlus;EPSD	TCGA;ICGC;COSMIC	9.540	Down-regulation
Atypical_PIKK_ATM_ATM_ST	Q8TAQ5	ZNF420	Q13315	ATM	S68	W70R	70	Missense	proximal	2	no	13.803	14.123	PhosphoSitePlus	TCGA;ICGC;COSMIC	9.540	Up-regulation
Atypical_PIKK_ATM_ATM_ST	Q8TAQ5	ZNF420	Q13315	ATM	S68	S68F	68	Missense	central	0	yes	13.803	0.000	PhosphoSitePlus	TCGA;ICGC;COSMIC	9.540	Loss
Atypical_PIKK_ATM_ATM_ST	Q8TAQ5	ZNF420	Q13315	ATM	S236	K243N	243	Missense	distal	7	no	11.865	11.857	EPSD	TCGA	9.540	Down-regulation
Atypical_PIKK_ATM_ATM_ST	Q8TAQ5	ZNF420	Q13315	ATM	S236	Q237H	237	Missense	proximal	1	no	11.865	-3.044	EPSD	TCGA;ICGC;COSMIC	9.540	Loss
Atypical_PIKK_ATM_ATM_ST	Q8TAQ5	ZNF420	Q13315	ATM	S236	F232L	232	Missense	distal	-4	no	11.865	12.324	EPSD	TCGA;ICGC;COSMIC	9.540	Up-regulation
Atypical_PIKK_ATM_ATM_ST	Q8TAQ5	ZNF420	Q13315	ATM	S236	R234C	234	Missense	proximal	-2	no	11.865	11.846	EPSD	TCGA;ICGC;COSMIC	9.540	Down-regulation
Atypical_PIKK_ATM_ATM_ST	Q8TAQ5	ZNF420	Q13315	ATM	S236	T239I	239	Missense	distal	3	no	11.865	12.286	EPSD	TCGA;ICGC	9.540	Up-regulation
Atypical_PIKK_ATM_ATM_ST	Q8TAQ5	ZNF420	Q13315	ATM	S236	K243T	243	Missense	distal	7	no	11.865	11.858	EPSD	TCGA;ICGC	9.540	Down-regulation
Atypical_PIKK_ATM_ATM_ST	Q8TAQ5	ZNF420	Q13315	ATM	S376	R383I	383	Missense	distal	7	no	12.568	12.564	EPSD	TCGA;ICGC;COSMIC	9.540	Down-regulation
Atypical_PIKK_ATM_ATM_ST	Q8TAQ5	ZNF420	Q13315	ATM	S376	L378F	378	Missense	proximal	2	no	12.568	12.333	EPSD	TCGA;ICGC;COSMIC	9.540	Down-regulation
Atypical_PIKK_ATM_ATM_ST	Q8TAQ5	ZNF420	Q13315	ATM	S376	F372L	372	Missense	distal	-4	no	12.568	13.027	EPSD	TCGA;ICGC;COSMIC	9.540	Up-regulation
Atypical_PIKK_ATM_ATM_ST	Q8TAQ5	ZNF420	Q13315	ATM	S404	Q410H	410	Missense	distal	6	no	12.116	12.104	EPSD	TCGA;ICGC;COSMIC	9.540	Down-regulation
Atypical_PIKK_ATM_ATM_ST	Q8TAQ5	ZNF420	Q13315	ATM	S488	R486C	486	Missense	proximal	-2	no	12.721	12.702	EPSD	TCGA;ICGC;COSMIC;GDSC;CCLE	9.540	Down-regulation
Atypical_PIKK_ATM_ATM_ST	Q8TAQ5	ZNF420	Q13315	ATM	S488	G481V	481	Missense	distal	-7	no	12.721	12.753	EPSD	TCGA	9.540	Up-regulation
Atypical_PIKK_ATM_ATM_ST	Q8TAQ5	ZNF420	Q13315	ATM	S488	R486H	486	Missense	proximal	-2	no	12.721	12.736	EPSD	TCGA;ICGC;COSMIC;GDSC;CCLE	9.540	Up-regulation
Atypical_PIKK_ATM_ATM_ST	Q8TAQ5	ZNF420	Q13315	ATM	S488	F484C	484	Missense	distal	-4	no	12.721	12.547	EPSD	TCGA;ICGC	9.540	Down-regulation
Atypical_PIKK_ATM_ATM_ST	Q8TAQ5	ZNF420	Q13315	ATM	S488	S488A	488	Missense	central	0	yes	12.721	0.000	EPSD	TCGA;ICGC	9.540	Loss
Atypical_PIKK_ATM_ATM_ST	Q8TAQ5	ZNF420	Q13315	ATM	S572	R570C	570	Missense	proximal	-2	no	12.581	12.562	EPSD	TCGA;ICGC;COSMIC	9.540	Down-regulation
Atypical_PIKK_ATM_ATM_ST	Q8TAQ5	ZNF420	Q13315	ATM	S572	R570S	570	Missense	proximal	-2	no	12.581	13.024	EPSD	TCGA;ICGC;COSMIC	9.540	Up-regulation
Atypical_PIKK_ATM_ATM_ST	Q8TAQ5	ZNF420	Q13315	ATM	S572	R579Q	579	Missense	distal	7	no	12.581	12.557	EPSD	TCGA;ICGC	9.540	Down-regulation
Atypical_PIKK_ATM_ATM_ST	Q9BXS6	NUSAP1	Q13315	ATM	S101	R96C	96	Missense	distal	-5	no	14.386	14.403	EPSD	TCGA;ICGC;COSMIC	9.540	Up-regulation
Atypical_PIKK_ATM_ATM_ST	Q9BXS6	NUSAP1	Q13315	ATM	S124	R128S	128	Missense	distal	4	no	15.956	15.774	PhosphoSitePlus	TCGA;COSMIC	9.540	Down-regulation
Atypical_PIKK_ATM_ATM_ST	Q9BXS6	NUSAP1	Q13315	ATM	S124	H119Y	119	Missense	distal	-5	no	15.956	15.931	PhosphoSitePlus	TCGA;COSMIC	9.540	Down-regulation
Atypical_PIKK_ATM_ATM_ST	Q9BXS6	NUSAP1	Q13315	ATM	S247	P245L	245	Missense	proximal	-2	no	13.192	13.039	EPSD	TCGA;ICGC;COSMIC	9.540	Down-regulation
Atypical_PIKK_ATM_ATM_ST	Q9BXS6	NUSAP1	Q13315	ATM	S247	S243Y	243	Missense	distal	-4	no	13.192	12.091	EPSD	TCGA;ICGC;COSMIC	9.540	Down-regulation
Atypical_PIKK_ATM_ATM_ST	Q9BXS6	NUSAP1	Q13315	ATM	S251	P245L	245	Missense	distal	-6	no	12.647	12.418	EPSD	TCGA;ICGC;COSMIC	9.540	Down-regulation
Atypical_PIKK_ATM_ATM_ST	Q9BXS6	NUSAP1	Q13315	ATM	S260	T263A	263	Missense	distal	3	no	14.491	14.466	EPSD	TCGA;ICGC;COSMIC	9.540	Down-regulation
Atypical_PIKK_ATM_ATM_ST	Q9BXS6	NUSAP1	Q13315	ATM	S260	Q261H	261	Missense	proximal	1	no	14.491	-0.418	EPSD	TCGA;ICGC;COSMIC	9.540	Loss
Atypical_PIKK_ATM_ATM_ST	Q9BXS6	NUSAP1	Q13315	ATM	T347	L342F	342	Missense	distal	-5	no	13.787	14.087	EPSD	TCGA;ICGC;COSMIC	9.540	Up-regulation
Atypical_PIKK_ATM_ATM_ST	Q9BXS6	NUSAP1	Q13315	ATM	T347	K354R	354	Missense	distal	7	no	13.787	13.799	EPSD	TCGA;ICGC	9.540	Up-regulation
Atypical_PIKK_ATM_ATM_ST	Q9BXS6	NUSAP1	Q13315	ATM	T347	T347M	347	Missense	central	0	yes	13.787	0.000	EPSD	TCGA;ICGC;COSMIC	9.540	Loss
Atypical_PIKK_ATM_ATM_ST	Q9BXS6	NUSAP1	Q13315	ATM	T347	N353D	353	Missense	distal	6	no	13.787	13.775	EPSD	TCGA;ICGC;COSMIC	9.540	Down-regulation
Atypical_PIKK_ATM_ATM_ST	Q9BXS6	NUSAP1	Q13315	ATM	S363	D359H	359	Missense	distal	-4	no	10.150	9.475	EPSD	TCGA;ICGC;COSMIC	9.540	Loss
Atypical_PIKK_ATM_ATM_ST	Q9NS91	RAD18	Q13315	ATM	T58	K52T	52	Missense	distal	-6	no	13.645	13.690	EPSD	TCGA;ICGC;COSMIC;GDSC;CCLE	9.540	Up-regulation
Atypical_PIKK_ATM_ATM_ST	Q9NS91	RAD18	Q13315	ATM	S146	S144F	144	Missense	proximal	-2	no	11.295	10.394	EPSD	TCGA;ICGC;COSMIC	9.540	Down-regulation
Atypical_PIKK_ATM_ATM_ST	Q9NS91	RAD18	Q13315	ATM	S146	E140K	140	Missense	distal	-6	no	11.295	10.994	EPSD	TCGA;ICGC	9.540	Down-regulation
Atypical_PIKK_ATM_ATM_ST	Q9NS91	RAD18	Q13315	ATM	S368	S368L	368	Missense	central	0	yes	11.741	0.000	EPSD	TCGA;ICGC;COSMIC	9.540	Loss
Atypical_PIKK_ATM_ATM_ST	Q9NS91	RAD18	Q13315	ATM	S409	E412K	412	Missense	distal	3	no	10.073	10.362	EPSD	TCGA;ICGC;COSMIC	9.540	Up-regulation
Atypical_PIKK_ATM_ATM_ST	Q9NS91	RAD18	Q13315	ATM	S471	L465I	465	Missense	distal	-6	no	10.322	10.209	EPSD	TCGA;ICGC;COSMIC	9.540	Down-regulation
Atypical_PIKK_ATM_ATM_ST	Q9NS91	RAD18	Q13315	ATM	S471	R477H	477	Missense	distal	6	no	10.322	10.306	EPSD	TCGA;ICGC;COSMIC;GDSC;CCLE	9.540	Down-regulation
Atypical_PIKK_ATM_ATM_ST	P15927	RPA2	Q13315	ATM	T21	T21P	21	Missense	central	0	yes	13.325	0.000	EPSD;PhosphoSitePlus	TCGA	9.540	Loss
Atypical_PIKK_ATM_ATM_ST	P15927	RPA2	Q13315	ATM	T21	S23F	23	Missense	proximal	2	no	13.325	11.847	EPSD;PhosphoSitePlus	TCGA;COSMIC	9.540	Down-regulation
Atypical_PIKK_ATM_ATM_ST	P15927	RPA2	Q13315	ATM	T21	G19D	19	Missense	proximal	-2	no	13.325	13.470	EPSD;PhosphoSitePlus	TCGA;COSMIC	9.540	Up-regulation
Atypical_PIKK_ATM_ATM_ST	P15927	RPA2	Q13315	ATM	T21	G26S	26	Missense	distal	5	no	13.325	13.147	EPSD;PhosphoSitePlus	TCGA;COSMIC	9.540	Down-regulation
Atypical_PIKK_ATM_ATM_ST	P15927	RPA2	Q13315	ATM	S23	T21P	21	Missense	proximal	-2	no	11.168	11.020	EPSD;PhosphoSitePlus	TCGA	9.540	Down-regulation
Atypical_PIKK_ATM_ATM_ST	P15927	RPA2	Q13315	ATM	S23	S23F	23	Missense	central	0	yes	11.168	0.000	EPSD;PhosphoSitePlus	TCGA;COSMIC	9.540	Loss
Atypical_PIKK_ATM_ATM_ST	P15927	RPA2	Q13315	ATM	S23	S29L	29	Missense	distal	6	no	11.168	11.112	EPSD;PhosphoSitePlus	TCGA;COSMIC	9.540	Down-regulation
Atypical_PIKK_ATM_ATM_ST	P15927	RPA2	Q13315	ATM	S23	G19D	19	Missense	distal	-4	no	11.168	11.952	EPSD;PhosphoSitePlus	TCGA;COSMIC	9.540	Up-regulation
Atypical_PIKK_ATM_ATM_ST	P15927	RPA2	Q13315	ATM	S23	G26S	26	Missense	distal	3	no	11.168	11.038	EPSD;PhosphoSitePlus	TCGA;COSMIC	9.540	Down-regulation
Atypical_PIKK_ATM_ATM_ST	P15927	RPA2	Q13315	ATM	S29	S23F	23	Missense	distal	-6	no	13.940	13.409	PhosphoSitePlus;EPSD	TCGA;COSMIC	9.540	Down-regulation
Atypical_PIKK_ATM_ATM_ST	P15927	RPA2	Q13315	ATM	S29	E36A	36	Missense	distal	7	no	13.940	13.975	PhosphoSitePlus;EPSD	TCGA;COSMIC	9.540	Up-regulation
Atypical_PIKK_ATM_ATM_ST	P15927	RPA2	Q13315	ATM	S29	S29L	29	Missense	central	0	yes	13.940	0.000	PhosphoSitePlus;EPSD	TCGA;COSMIC	9.540	Loss
Atypical_PIKK_ATM_ATM_ST	P15927	RPA2	Q13315	ATM	S29	G26S	26	Missense	distal	-3	no	13.940	13.662	PhosphoSitePlus;EPSD	TCGA;COSMIC	9.540	Down-regulation
Atypical_PIKK_ATM_ATM_ST	P15927	RPA2	Q13315	ATM	S33	E36A	36	Missense	distal	3	no	13.045	13.276	EPSD	TCGA;COSMIC	9.540	Up-regulation
Atypical_PIKK_ATM_ATM_ST	P15927	RPA2	Q13315	ATM	S33	S29L	29	Missense	distal	-4	no	13.045	12.105	EPSD	TCGA;COSMIC	9.540	Down-regulation
Atypical_PIKK_ATM_ATM_ST	P15927	RPA2	Q13315	ATM	S33	G26S	26	Missense	distal	-7	no	13.045	13.557	EPSD	TCGA;COSMIC	9.540	Up-regulation
Atypical_PIKK_ATM_ATM_ST	P15927	RPA2	Q13315	ATM	S33	S39A	39	Missense	distal	6	no	13.045	13.051	EPSD	TCGA;COSMIC	9.540	Up-regulation
Atypical_PIKK_ATM_ATM_ST	P15927	RPA2	Q13315	ATM	S52	Q53H	53	Missense	proximal	1	no	14.328	-0.581	EPSD	TCGA;COSMIC	9.540	Loss
Atypical_PIKK_ATM_ATM_ST	P15927	RPA2	Q13315	ATM	S52	A57V	57	Missense	distal	5	no	14.328	14.492	EPSD	TCGA;COSMIC	9.540	Up-regulation
Atypical_PIKK_ATM_ATM_ST	P15927	RPA2	Q13315	ATM	S72	G67W	67	Missense	distal	-5	no	14.027	14.213	EPSD	TCGA;COSMIC	9.540	Up-regulation
Atypical_PIKK_ATM_ATM_ST	P15927	RPA2	Q13315	ATM	S115	D109G	109	Missense	distal	-6	no	9.648	9.473	EPSD	TCGA;COSMIC	9.540	Loss
Atypical_PIKK_ATM_ATM_ST	P15927	RPA2	Q13315	ATM	S115	T118A	118	Missense	distal	3	no	9.648	9.624	EPSD	TCGA	9.540	Down-regulation
Atypical_PIKK_ATM_ATM_ST	Q9UBU7	DBF4	Q13315	ATM	S84	F78C	78	Missense	distal	-6	no	10.785	10.936	EPSD	TCGA;ICGC;COSMIC	9.540	Up-regulation
Atypical_PIKK_ATM_ATM_ST	Q9UBU7	DBF4	Q13315	ATM	S84	Y85H	85	Missense	proximal	1	no	10.785	1.592	EPSD	TCGA;ICGC;COSMIC	9.540	Loss
Atypical_PIKK_ATM_ATM_ST	Q9UBU7	DBF4	Q13315	ATM	S118	H120D	120	Missense	proximal	2	no	8.564	9.625	EPSD	TCGA;ICGC	9.540	Gain
Atypical_PIKK_ATM_ATM_ST	Q9UBU7	DBF4	Q13315	ATM	S381	S381C	381	Missense	central	0	yes	14.687	0.000	EPSD	TCGA;ICGC;COSMIC	9.540	Loss
Atypical_PIKK_ATM_ATM_ST	Q9UBU7	DBF4	Q13315	ATM	S381	S381Y	381	Missense	central	0	yes	14.687	0.000	EPSD	TCGA;ICGC;COSMIC	9.540	Loss
Atypical_PIKK_ATM_ATM_ST	Q9UBU7	DBF4	Q13315	ATM	T449	L453V	453	Missense	distal	4	no	13.057	13.021	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	9.540	Down-regulation
Atypical_PIKK_ATM_ATM_ST	Q9UBU7	DBF4	Q13315	ATM	T449	L453Q	453	Missense	distal	4	no	13.057	12.748	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	9.540	Down-regulation
Atypical_PIKK_ATM_ATM_ST	Q9UBU7	DBF4	Q13315	ATM	T449	R445I	445	Missense	distal	-4	no	13.057	13.155	EPSD;PhosphoSitePlus	TCGA;ICGC	9.540	Up-regulation
Atypical_PIKK_ATM_ATM_ST	Q9UBU7	DBF4	Q13315	ATM	S539	L543V	543	Missense	distal	4	no	14.650	14.614	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	9.540	Down-regulation
Atypical_PIKK_ATM_ATM_ST	Q9UBU7	DBF4	Q13315	ATM	S539	S538G	538	Missense	proximal	-1	no	14.650	14.458	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	9.540	Down-regulation
Atypical_PIKK_ATM_ATM_ST	Q9UBU7	DBF4	Q13315	ATM	S539	G532D	532	Missense	distal	-7	no	14.650	14.940	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	9.540	Up-regulation
Atypical_PIKK_ATM_ATM_ST	Q9UBU7	DBF4	Q13315	ATM	S539	H542D	542	Missense	distal	3	no	14.650	14.610	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	9.540	Down-regulation
Atypical_PIKK_ATM_ATM_ST	Q9UBU7	DBF4	Q13315	ATM	S629	F622L	622	Missense	distal	-7	no	9.361	9.603	EPSD	TCGA;ICGC;COSMIC	9.540	Gain
Atypical_PIKK_ATM_ATM_ST	Q9UBU7	DBF4	Q13315	ATM	S665	S664L	664	Missense	proximal	-1	no	9.848	9.713	EPSD	TCGA;ICGC	9.540	Down-regulation
Atypical_PIKK_ATM_ATM_ST	P41236	PPP1R2	Q13315	ATM	S44	D48N	48	Missense	distal	4	no	13.291	13.211	PhosphoSitePlus	TCGA;ICGC	9.540	Down-regulation
Atypical_PIKK_ATM_ATM_ST	Q14247	CTTN	Q13315	ATM	S109	S113L	113	Missense	distal	4	no	9.277	9.619	EPSD	TCGA;ICGC;COSMIC;GDSC;CCLE	9.540	Gain
Atypical_PIKK_ATM_ATM_ST	Q14247	CTTN	Q13315	ATM	S113	G120V	120	Missense	distal	7	no	14.639	14.646	PhosphoSitePlus	TCGA;ICGC;COSMIC	9.540	Up-regulation
Atypical_PIKK_ATM_ATM_ST	Q14247	CTTN	Q13315	ATM	S113	Q114P	114	Missense	proximal	1	no	14.639	9.837	PhosphoSitePlus	TCGA;ICGC;COSMIC	9.540	Down-regulation
Atypical_PIKK_ATM_ATM_ST	Q14247	CTTN	Q13315	ATM	S113	S113L	113	Missense	central	0	yes	14.639	0.000	PhosphoSitePlus	TCGA;ICGC;COSMIC;GDSC;CCLE	9.540	Loss
Atypical_PIKK_ATM_ATM_ST	Q14247	CTTN	Q13315	ATM	S150	E146G	146	Missense	distal	-4	no	13.584	12.517	EPSD	TCGA;ICGC;COSMIC	9.540	Down-regulation
Atypical_PIKK_ATM_ATM_ST	Q14247	CTTN	Q13315	ATM	S150	S155F	155	Missense	distal	5	no	13.584	13.890	EPSD	TCGA;ICGC;COSMIC	9.540	Up-regulation
Atypical_PIKK_ATM_ATM_ST	Q14247	CTTN	Q13315	ATM	S150	G143R	143	Missense	distal	-7	no	13.584	13.698	EPSD	TCGA;ICGC;COSMIC	9.540	Up-regulation
Atypical_PIKK_ATM_ATM_ST	Q14247	CTTN	Q13315	ATM	S187	R189K	189	Missense	proximal	2	no	13.838	14.016	EPSD	TCGA;ICGC;COSMIC	9.540	Up-regulation
Atypical_PIKK_ATM_ATM_ST	Q14247	CTTN	Q13315	ATM	S187	S192F	192	Missense	distal	5	no	13.838	14.145	EPSD	TCGA;ICGC;COSMIC	9.540	Up-regulation
Atypical_PIKK_ATM_ATM_ST	Q14247	CTTN	Q13315	ATM	S187	H185L	185	Missense	proximal	-2	no	13.838	13.876	EPSD	TCGA;ICGC;COSMIC	9.540	Up-regulation
Atypical_PIKK_ATM_ATM_ST	Q14247	CTTN	Q13315	ATM	S224	H222R	222	Missense	proximal	-2	no	14.223	14.208	EPSD	TCGA;ICGC;COSMIC	9.540	Down-regulation
Atypical_PIKK_ATM_ATM_ST	Q14247	CTTN	Q13315	ATM	S224	T219M	219	Missense	distal	-5	no	14.223	14.397	EPSD	TCGA;ICGC;COSMIC	9.540	Up-regulation
Atypical_PIKK_ATM_ATM_ST	Q14247	CTTN	Q13315	ATM	S261	L256M	256	Missense	distal	-5	no	15.291	15.353	EPSD	TCGA;ICGC;COSMIC	9.540	Up-regulation
Atypical_PIKK_ATM_ATM_ST	Q9Y6D9	MAD1L1	Q13315	ATM	S22	S16F	16	Missense	distal	-6	no	12.975	12.444	EPSD	TCGA;ICGC;COSMIC	9.540	Down-regulation
Atypical_PIKK_ATM_ATM_ST	Q9Y6D9	MAD1L1	Q13315	ATM	S22	R24L	24	Missense	proximal	2	no	12.975	12.729	EPSD	TCGA;ICGC;COSMIC	9.540	Down-regulation
Atypical_PIKK_ATM_ATM_ST	Q9Y6D9	MAD1L1	Q13315	ATM	S92	A89S	89	Missense	distal	-3	no	9.250	9.695	EPSD	TCGA;ICGC;COSMIC	9.540	Gain
Atypical_PIKK_ATM_ATM_ST	Q9Y6D9	MAD1L1	Q13315	ATM	S185	E184K	184	Missense	proximal	-1	no	9.557	9.155	EPSD	TCGA;COSMIC	9.540	Loss
Atypical_PIKK_ATM_ATM_ST	Q9Y6D9	MAD1L1	Q13315	ATM	S185	R179L	179	Missense	distal	-6	no	9.557	9.450	EPSD	TCGA;COSMIC	9.540	Loss
Atypical_PIKK_ATM_ATM_ST	Q9Y6D9	MAD1L1	Q13315	ATM	S185	M178L	178	Missense	distal	-7	no	9.557	9.445	EPSD	TCGA;COSMIC	9.540	Loss
Atypical_PIKK_ATM_ATM_ST	Q9Y6D9	MAD1L1	Q13315	ATM	S185	R179Q	179	Missense	distal	-6	no	9.557	9.701	EPSD	TCGA;COSMIC	9.540	Up-regulation
Atypical_PIKK_ATM_ATM_ST	Q9Y6D9	MAD1L1	Q13315	ATM	S185	R182H	182	Missense	distal	-3	no	9.557	8.912	EPSD	TCGA;COSMIC;GDSC;CCLE	9.540	Loss
Atypical_PIKK_ATM_ATM_ST	Q9Y6D9	MAD1L1	Q13315	ATM	S214	R218K	218	Missense	distal	4	no	15.744	15.642	PhosphoSitePlus	TCGA;COSMIC	9.540	Down-regulation
Atypical_PIKK_ATM_ATM_ST	Q9Y6D9	MAD1L1	Q13315	ATM	S428	Q430H	430	Missense	proximal	2	no	10.144	9.764	EPSD	TCGA;COSMIC	9.540	Down-regulation
Atypical_PIKK_ATM_ATM_ST	Q9Y6D9	MAD1L1	Q13315	ATM	S457	E461D	461	Missense	distal	4	no	14.216	14.722	EPSD	TCGA	9.540	Up-regulation
Atypical_PIKK_ATM_ATM_ST	Q9Y6D9	MAD1L1	Q13315	ATM	S457	G464R	464	Missense	distal	7	no	14.216	14.210	EPSD	TCGA;COSMIC	9.540	Down-regulation
Atypical_PIKK_ATM_ATM_ST	Q9Y6D9	MAD1L1	Q13315	ATM	S457	S457L	457	Missense	central	0	yes	14.216	0.000	EPSD	TCGA	9.540	Loss
Atypical_PIKK_ATM_ATM_ST	Q9Y6D9	MAD1L1	Q13315	ATM	S457	E451K	451	Missense	distal	-6	no	14.216	13.916	EPSD	TCGA	9.540	Down-regulation
Atypical_PIKK_ATM_ATM_ST	Q9Y6D9	MAD1L1	Q13315	ATM	S482	E488K	488	Missense	distal	6	no	14.332	14.286	EPSD	TCGA;COSMIC	9.540	Down-regulation
Atypical_PIKK_ATM_ATM_ST	Q9Y6D9	MAD1L1	Q13315	ATM	S482	K478N	478	Missense	distal	-4	no	14.332	14.097	EPSD	TCGA;COSMIC	9.540	Down-regulation
Atypical_PIKK_ATM_ATM_ST	Q9Y6D9	MAD1L1	Q13315	ATM	S494	E496V	496	Missense	proximal	2	no	10.044	8.641	EPSD	TCGA;COSMIC	9.540	Loss
Atypical_PIKK_ATM_ATM_ST	Q9Y6D9	MAD1L1	Q13315	ATM	S494	E488K	488	Missense	distal	-6	no	10.044	9.743	EPSD	TCGA;COSMIC	9.540	Down-regulation
Atypical_PIKK_ATM_ATM_ST	Q9Y6D9	MAD1L1	Q13315	ATM	S494	S490G	490	Missense	distal	-4	no	10.044	9.255	EPSD	TCGA;COSMIC	9.540	Loss
Atypical_PIKK_ATM_ATM_ST	Q9Y6D9	MAD1L1	Q13315	ATM	S562	R556C	556	Missense	distal	-6	no	14.822	14.622	EPSD	TCGA;COSMIC;CCLE	9.540	Down-regulation
Atypical_PIKK_ATM_ATM_ST	Q9Y6D9	MAD1L1	Q13315	ATM	S562	R556H	556	Missense	distal	-6	no	14.822	14.823	EPSD	TCGA;COSMIC	9.540	Up-regulation
Atypical_PIKK_ATM_ATM_ST	Q9Y6D9	MAD1L1	Q13315	ATM	S610	K614N	614	Missense	distal	4	no	9.855	9.902	EPSD	TCGA;COSMIC	9.540	Up-regulation
Atypical_PIKK_ATM_ATM_ST	Q9Y6D9	MAD1L1	Q13315	ATM	S610	Q607R	607	Missense	distal	-3	no	9.855	10.630	EPSD	TCGA;COSMIC	9.540	Up-regulation
Atypical_PIKK_ATM_ATM_ST	Q9Y6D9	MAD1L1	Q13315	ATM	S713	T708I	708	Missense	distal	-5	no	9.352	9.555	EPSD	TCGA;COSMIC	9.540	Gain
Atypical_PIKK_ATM_ATM_ST	P15374	UCHL3	Q13315	ATM	S130	S130I	130	Missense	central	0	yes	10.957	0.000	EPSD	TCGA;ICGC;COSMIC	9.540	Loss
Atypical_PIKK_ATM_ATM_ST	P15374	UCHL3	Q13315	ATM	S130	R136K	136	Missense	distal	6	no	10.957	10.953	EPSD	TCGA;ICGC;COSMIC	9.540	Down-regulation
Atypical_PIKK_ATM_ATM_ST	P15374	UCHL3	Q13315	ATM	S130	L123M	123	Missense	distal	-7	no	10.957	11.069	EPSD	TCGA;ICGC;COSMIC	9.540	Up-regulation
Atypical_PIKK_ATM_ATM_ST	Q70CQ2	USP34	Q13315	ATM	S143	K141N	141	Missense	proximal	-2	no	9.892	10.107	EPSD	TCGA;ICGC;COSMIC	9.540	Up-regulation
Atypical_PIKK_ATM_ATM_ST	Q70CQ2	USP34	Q13315	ATM	S143	W149C	149	Missense	distal	6	no	9.892	9.869	EPSD	TCGA;ICGC;COSMIC	9.540	Down-regulation
Atypical_PIKK_ATM_ATM_ST	Q70CQ2	USP34	Q13315	ATM	S143	E137D	137	Missense	distal	-6	no	9.892	9.677	EPSD	TCGA;ICGC	9.540	Down-regulation
Atypical_PIKK_ATM_ATM_ST	Q70CQ2	USP34	Q13315	ATM	T188	T188I	188	Missense	central	0	yes	13.341	0.000	EPSD	TCGA;ICGC	9.540	Loss
Atypical_PIKK_ATM_ATM_ST	Q70CQ2	USP34	Q13315	ATM	T188	S187L	187	Missense	proximal	-1	no	13.341	13.206	EPSD	TCGA;ICGC;COSMIC	9.540	Down-regulation
Atypical_PIKK_ATM_ATM_ST	Q70CQ2	USP34	Q13315	ATM	T188	G195R	195	Missense	distal	7	no	13.341	13.334	EPSD	TCGA;ICGC;COSMIC	9.540	Down-regulation
Atypical_PIKK_ATM_ATM_ST	Q70CQ2	USP34	Q13315	ATM	T188	S191R	191	Missense	distal	3	no	13.341	13.526	EPSD	TCGA;ICGC;COSMIC	9.540	Up-regulation
Atypical_PIKK_ATM_ATM_ST	Q70CQ2	USP34	Q13315	ATM	T188	I193T	193	Missense	distal	5	no	13.341	13.115	EPSD	TCGA;ICGC;COSMIC	9.540	Down-regulation
Atypical_PIKK_ATM_ATM_ST	Q70CQ2	USP34	Q13315	ATM	S324	S324P	324	Missense	central	0	yes	10.765	0.000	EPSD	TCGA;ICGC;COSMIC	9.540	Loss
Atypical_PIKK_ATM_ATM_ST	Q70CQ2	USP34	Q13315	ATM	S649	I653V	653	Missense	distal	4	no	14.044	13.687	EPSD	TCGA;ICGC;COSMIC	9.540	Down-regulation
Atypical_PIKK_ATM_ATM_ST	Q70CQ2	USP34	Q13315	ATM	S649	R643Q	643	Missense	distal	-6	no	14.044	14.187	EPSD	TCGA;ICGC;COSMIC	9.540	Up-regulation
Atypical_PIKK_ATM_ATM_ST	Q70CQ2	USP34	Q13315	ATM	S658	I653V	653	Missense	distal	-5	no	12.913	12.912	EPSD	TCGA;ICGC;COSMIC	9.540	Down-regulation
Atypical_PIKK_ATM_ATM_ST	Q70CQ2	USP34	Q13315	ATM	S718	R725Q	725	Missense	distal	7	no	15.869	15.844	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC;GDSC;CCLE	9.540	Down-regulation
Atypical_PIKK_ATM_ATM_ST	Q70CQ2	USP34	Q13315	ATM	T724	R725Q	725	Missense	proximal	1	no	7.783	14.434	EPSD	TCGA;ICGC;COSMIC;GDSC;CCLE	9.540	Gain
Atypical_PIKK_ATM_ATM_ST	Q70CQ2	USP34	Q13315	ATM	S832	V836I	836	Missense	distal	4	no	12.174	12.531	EPSD	TCGA;ICGC	9.540	Up-regulation
Atypical_PIKK_ATM_ATM_ST	Q70CQ2	USP34	Q13315	ATM	S832	H838R	838	Missense	distal	6	no	12.174	12.190	EPSD	TCGA;ICGC;COSMIC	9.540	Up-regulation
Atypical_PIKK_ATM_ATM_ST	Q70CQ2	USP34	Q13315	ATM	S832	H828Q	828	Missense	distal	-4	no	12.174	12.409	EPSD	TCGA;ICGC;COSMIC	9.540	Up-regulation
Atypical_PIKK_ATM_ATM_ST	Q70CQ2	USP34	Q13315	ATM	S920	R922H	922	Missense	proximal	2	no	11.689	12.005	EPSD	TCGA;ICGC;COSMIC	9.540	Up-regulation
Atypical_PIKK_ATM_ATM_ST	Q70CQ2	USP34	Q13315	ATM	S920	R922C	922	Missense	proximal	2	no	11.689	11.432	EPSD	TCGA;ICGC;COSMIC	9.540	Down-regulation
Atypical_PIKK_ATM_ATM_ST	Q70CQ2	USP34	Q13315	ATM	S920	S916L	916	Missense	distal	-4	no	11.689	10.749	EPSD	TCGA;ICGC;COSMIC	9.540	Down-regulation
Atypical_PIKK_ATM_ATM_ST	Q70CQ2	USP34	Q13315	ATM	S1152	E1154K	1154	Missense	proximal	2	no	10.297	8.966	EPSD	TCGA;ICGC;COSMIC	9.540	Loss
Atypical_PIKK_ATM_ATM_ST	Q70CQ2	USP34	Q13315	ATM	S1375	E1376K	1376	Missense	proximal	1	no	10.765	9.813	EPSD	TCGA;ICGC;COSMIC	9.540	Down-regulation
Atypical_PIKK_ATM_ATM_ST	Q70CQ2	USP34	Q13315	ATM	S1473	S1469L	1469	Missense	distal	-4	no	12.350	11.411	EPSD	TCGA;ICGC;COSMIC	9.540	Down-regulation
Atypical_PIKK_ATM_ATM_ST	Q70CQ2	USP34	Q13315	ATM	S1994	I1990S	1990	Missense	distal	-4	no	11.193	11.904	EPSD	TCGA;ICGC;COSMIC	9.540	Up-regulation
Atypical_PIKK_ATM_ATM_ST	Q70CQ2	USP34	Q13315	ATM	S1994	E1991D	1991	Missense	distal	-3	no	11.193	11.598	EPSD	TCGA;ICGC;COSMIC	9.540	Up-regulation
Atypical_PIKK_ATM_ATM_ST	Q70CQ2	USP34	Q13315	ATM	S1994	P1995S	1995	Missense	proximal	1	no	11.193	4.218	EPSD	TCGA;ICGC;COSMIC	9.540	Loss
Atypical_PIKK_ATM_ATM_ST	Q70CQ2	USP34	Q13315	ATM	S2339	Q2340H	2340	Missense	proximal	1	no	14.238	-0.671	EPSD	TCGA;ICGC;COSMIC;GDSC;CCLE	9.540	Loss
Atypical_PIKK_ATM_ATM_ST	Q70CQ2	USP34	Q13315	ATM	S2339	L2332F	2332	Missense	distal	-7	no	14.238	13.996	EPSD	TCGA;ICGC;COSMIC	9.540	Down-regulation
Atypical_PIKK_ATM_ATM_ST	Q70CQ2	USP34	Q13315	ATM	S2339	W2345R	2345	Missense	distal	6	no	14.238	14.270	EPSD	TCGA;ICGC;COSMIC	9.540	Up-regulation
Atypical_PIKK_ATM_ATM_ST	Q70CQ2	USP34	Q13315	ATM	S2339	T2333M	2333	Missense	distal	-6	no	14.238	14.062	EPSD	TCGA;ICGC;CCLE	9.540	Down-regulation
Atypical_PIKK_ATM_ATM_ST	Q70CQ2	USP34	Q13315	ATM	S2706	R2702Q	2702	Missense	distal	-4	no	9.520	9.885	EPSD	TCGA;ICGC;COSMIC	9.540	Gain
Atypical_PIKK_ATM_ATM_ST	Q70CQ2	USP34	Q13315	ATM	S2706	R2705M	2705	Missense	proximal	-1	no	9.520	9.603	EPSD	TCGA;ICGC;COSMIC	9.540	Gain
Atypical_PIKK_ATM_ATM_ST	Q70CQ2	USP34	Q13315	ATM	T3195	A3198V	3198	Missense	distal	3	no	13.155	13.443	EPSD	TCGA;ICGC;COSMIC	9.540	Up-regulation
Atypical_PIKK_ATM_ATM_ST	Q70CQ2	USP34	Q13315	ATM	T3350	R3356C	3356	Missense	distal	6	no	10.611	10.556	EPSD	TCGA;ICGC;COSMIC	9.540	Down-regulation
Atypical_PIKK_ATM_ATM_ST	Q70CQ2	USP34	Q13315	ATM	T3350	R3355W	3355	Missense	distal	5	no	10.611	10.635	EPSD	TCGA;ICGC;COSMIC;GDSC;CCLE	9.540	Up-regulation
Atypical_PIKK_ATM_ATM_ST	Q70CQ2	USP34	Q13315	ATM	S3406	N3409Y	3409	Missense	distal	3	no	10.292	10.333	EPSD	TCGA;ICGC;COSMIC	9.540	Up-regulation
Atypical_PIKK_ATM_ATM_ST	Q70CQ2	USP34	Q13315	ATM	S3406	S3411Y	3411	Missense	distal	5	no	10.292	10.356	EPSD	TCGA;ICGC;COSMIC	9.540	Up-regulation
Atypical_PIKK_ATM_ATM_ST	Q70CQ2	USP34	Q13315	ATM	S3406	K3413I	3413	Missense	distal	7	no	10.292	10.300	EPSD	TCGA;ICGC;COSMIC	9.540	Up-regulation
Atypical_PIKK_ATM_ATM_ST	Q70CQ2	USP34	Q13315	ATM	S3422	F3423L	3423	Missense	proximal	1	no	5.756	9.637	EPSD	TCGA;ICGC;COSMIC	9.540	Gain
Atypical_PIKK_ATM_ATM_ST	Q13769	THOC5	Q13315	ATM	T536	F535L	535	Missense	proximal	-1	no	10.670	10.961	EPSD	TCGA;ICGC;COSMIC	9.540	Up-regulation
Atypical_PIKK_ATM_ATM_ST	Q13769	THOC5	Q13315	ATM	T536	A542V	542	Missense	distal	6	no	10.670	10.640	EPSD	TCGA;ICGC;COSMIC	9.540	Down-regulation
Atypical_PIKK_ATM_ATM_ST	Q13769	THOC5	Q13315	ATM	T536	M531V	531	Missense	distal	-5	no	10.670	10.699	EPSD	TCGA;ICGC;COSMIC	9.540	Up-regulation
Atypical_PIKK_ATM_ATM_ST	Q9UQE7	SMC3	Q13315	ATM	S133	N134Y	134	Missense	proximal	1	no	6.245	10.390	EPSD	TCGA;ICGC;COSMIC	9.540	Gain
Atypical_PIKK_ATM_ATM_ST	Q9UQE7	SMC3	Q13315	ATM	S177	K180N	180	Missense	distal	3	no	10.314	10.402	EPSD	TCGA;ICGC;COSMIC	9.540	Up-regulation
Atypical_PIKK_ATM_ATM_ST	Q9UQE7	SMC3	Q13315	ATM	T347	E346K	346	Missense	proximal	-1	no	9.679	9.276	EPSD	TCGA;ICGC;COSMIC	9.540	Loss
Atypical_PIKK_ATM_ATM_ST	Q9UQE7	SMC3	Q13315	ATM	T640	S639L	639	Missense	proximal	-1	no	10.150	10.014	EPSD	TCGA;ICGC;COSMIC	9.540	Down-regulation
Atypical_PIKK_ATM_ATM_ST	Q9UQE7	SMC3	Q13315	ATM	T640	R644C	644	Missense	distal	4	no	10.150	10.477	EPSD	TCGA	9.540	Up-regulation
Atypical_PIKK_ATM_ATM_ST	Q9UQE7	SMC3	Q13315	ATM	S731	S731C	731	Missense	central	0	yes	10.330	0.000	EPSD	TCGA;ICGC;COSMIC	9.540	Loss
Atypical_PIKK_ATM_ATM_ST	Q9UQE7	SMC3	Q13315	ATM	S1065	G1064D	1064	Missense	proximal	-1	no	15.087	15.224	EPSD	TCGA;ICGC;COSMIC	9.540	Up-regulation
Atypical_PIKK_ATM_ATM_ST	Q9UQE7	SMC3	Q13315	ATM	S1065	S1065I	1065	Missense	central	0	yes	15.087	0.000	EPSD	TCGA;ICGC;COSMIC	9.540	Loss
Atypical_PIKK_ATM_ATM_ST	Q9UQE7	SMC3	Q13315	ATM	S1065	G1060V	1060	Missense	distal	-5	no	15.087	15.146	EPSD	TCGA;ICGC;COSMIC	9.540	Up-regulation
Atypical_PIKK_ATM_ATM_ST	Q9UQE7	SMC3	Q13315	ATM	S1067	G1064D	1064	Missense	distal	-3	no	16.314	16.282	EPSD	TCGA;ICGC;COSMIC	9.540	Down-regulation
Atypical_PIKK_ATM_ATM_ST	Q9UQE7	SMC3	Q13315	ATM	S1067	S1065I	1065	Missense	proximal	-2	no	16.314	15.624	EPSD	TCGA;ICGC;COSMIC	9.540	Down-regulation
Atypical_PIKK_ATM_ATM_ST	Q9UQE7	SMC3	Q13315	ATM	S1067	G1060V	1060	Missense	distal	-7	no	16.314	16.346	EPSD	TCGA;ICGC;COSMIC	9.540	Up-regulation
Atypical_PIKK_ATM_ATM_ST	Q13315	ATM	Q13315	ATM	T86	K93N	93	Missense	distal	7	no	13.802	13.794	EPSD	TCGA;ICGC;COSMIC	9.540	Down-regulation
Atypical_PIKK_ATM_ATM_ST	Q13315	ATM	Q13315	ATM	T86	P80S	80	Missense	distal	-6	no	13.802	13.861	EPSD	TCGA;ICGC;COSMIC	9.540	Up-regulation
Atypical_PIKK_ATM_ATM_ST	Q13315	ATM	Q13315	ATM	S89	K93N	93	Missense	distal	4	no	9.520	9.567	EPSD	TCGA;ICGC;COSMIC	9.540	Gain
Atypical_PIKK_ATM_ATM_ST	Q13315	ATM	Q13315	ATM	S200	S207C	207	Missense	distal	7	no	14.132	14.184	EPSD	TCGA;ICGC;COSMIC	9.540	Up-regulation
Atypical_PIKK_ATM_ATM_ST	Q13315	ATM	Q13315	ATM	S200	G204R	204	Missense	distal	4	no	14.132	14.185	EPSD	TCGA;ICGC;COSMIC	9.540	Up-regulation
Atypical_PIKK_ATM_ATM_ST	Q13315	ATM	Q13315	ATM	T297	P292L	292	Missense	distal	-5	no	14.760	14.779	EPSD	TCGA;ICGC;COSMIC	9.540	Up-regulation
Atypical_PIKK_ATM_ATM_ST	Q13315	ATM	Q13315	ATM	T297	E299D	299	Missense	proximal	2	no	14.760	14.629	EPSD	TCGA;ICGC;COSMIC	9.540	Down-regulation
Atypical_PIKK_ATM_ATM_ST	Q13315	ATM	Q13315	ATM	T297	A295P	295	Missense	proximal	-2	no	14.760	14.711	EPSD	TCGA;ICGC;COSMIC	9.540	Down-regulation
Atypical_PIKK_ATM_ATM_ST	Q13315	ATM	Q13315	ATM	T297	H290Y	290	Missense	distal	-7	no	14.760	14.778	EPSD	TCGA;ICGC;COSMIC	9.540	Up-regulation
Atypical_PIKK_ATM_ATM_ST	Q13315	ATM	Q13315	ATM	T297	K296R	296	Missense	proximal	-1	no	14.760	14.578	EPSD	TCGA;ICGC	9.540	Down-regulation
Atypical_PIKK_ATM_ATM_ST	Q13315	ATM	Q13315	ATM	T297	G301S	301	Missense	distal	4	no	14.760	14.631	EPSD	TCGA;ICGC;COSMIC	9.540	Down-regulation
Atypical_PIKK_ATM_ATM_ST	Q13315	ATM	Q13315	ATM	S367	Q368E	368	Missense	proximal	1	no	15.079	9.182	PhosphoSitePlus;EPSD	TCGA;ICGC;COSMIC	9.540	Loss
Atypical_PIKK_ATM_ATM_ST	Q13315	ATM	Q13315	ATM	S369	Q368E	368	Missense	proximal	-1	no	10.128	10.406	EPSD	TCGA;ICGC;COSMIC	9.540	Up-regulation
Atypical_PIKK_ATM_ATM_ST	Q13315	ATM	Q13315	ATM	T373	Q368E	368	Missense	distal	-5	no	13.680	13.648	EPSD	TCGA;ICGC;COSMIC	9.540	Down-regulation
Atypical_PIKK_ATM_ATM_ST	Q13315	ATM	Q13315	ATM	S440	S433Y	433	Missense	distal	-7	no	13.724	13.429	EPSD;PhosphoSitePlus	TCGA;ICGC	9.540	Down-regulation
Atypical_PIKK_ATM_ATM_ST	Q13315	ATM	Q13315	ATM	S440	S440F	440	Missense	central	0	yes	13.724	0.000	EPSD;PhosphoSitePlus	TCGA;ICGC	9.540	Loss
Atypical_PIKK_ATM_ATM_ST	Q13315	ATM	Q13315	ATM	S646	E642K	642	Missense	distal	-4	no	10.013	9.041	EPSD	TCGA;ICGC;COSMIC	9.540	Loss
Atypical_PIKK_ATM_ATM_ST	Q13315	ATM	Q13315	ATM	S646	E649D	649	Missense	distal	3	no	10.013	10.372	EPSD	TCGA;ICGC;COSMIC	9.540	Up-regulation
Atypical_PIKK_ATM_ATM_ST	Q13315	ATM	Q13315	ATM	S1878	T1871I	1871	Missense	distal	-7	no	14.356	13.773	EPSD	TCGA;ICGC;COSMIC	9.540	Down-regulation
Atypical_PIKK_ATM_ATM_ST	Q13315	ATM	Q13315	ATM	S1878	R1882Q	1882	Missense	distal	4	no	14.356	14.207	EPSD	TCGA;ICGC;COSMIC	9.540	Down-regulation
Atypical_PIKK_ATM_ATM_ST	Q13315	ATM	Q13315	ATM	S1881	R1882Q	1882	Missense	proximal	1	no	7.561	14.212	EPSD	TCGA;ICGC;COSMIC	9.540	Gain
Atypical_PIKK_ATM_ATM_ST	Q13315	ATM	Q13315	ATM	T1885	R1882Q	1882	Missense	distal	-3	no	12.155	11.381	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	9.540	Down-regulation
Atypical_PIKK_ATM_ATM_ST	Q13315	ATM	Q13315	ATM	S1893	R1898Q	1898	Missense	distal	5	no	11.705	11.593	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	9.540	Down-regulation
Atypical_PIKK_ATM_ATM_ST	Q13315	ATM	Q13315	ATM	S2000	L2005I	2005	Missense	distal	5	no	9.944	9.989	EPSD	TCGA;ICGC;COSMIC	9.540	Up-regulation
Atypical_PIKK_ATM_ATM_ST	Q13315	ATM	Q13315	ATM	S2000	G1998E	1998	Missense	proximal	-2	no	9.944	10.567	EPSD	TCGA;ICGC;COSMIC;GDSC;CCLE	9.540	Up-regulation
Atypical_PIKK_ATM_ATM_ST	Q13315	ATM	Q13315	ATM	S2000	D2003E	2003	Missense	distal	3	no	9.944	9.585	EPSD	TCGA;ICGC;COSMIC	9.540	Down-regulation
Atypical_PIKK_ATM_ATM_ST	Q13315	ATM	Q13315	ATM	S2242	E2238Q	2238	Missense	distal	-4	no	14.683	13.960	EPSD	TCGA;ICGC;COSMIC	9.540	Down-regulation
Atypical_PIKK_ATM_ATM_ST	Q13315	ATM	Q13315	ATM	S2592	R2598Q	2598	Missense	distal	6	no	13.755	13.750	EPSD	TCGA;ICGC;COSMIC	9.540	Down-regulation
Atypical_PIKK_ATM_ATM_ST	Q13315	ATM	Q13315	ATM	S2996	Q3000H	3000	Missense	distal	4	no	11.474	11.558	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	9.540	Up-regulation
Atypical_PIKK_ATM_ATM_ST	Q13315	ATM	Q13315	ATM	S2996	D2997N	2997	Missense	proximal	1	no	11.474	7.643	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	9.540	Loss
Atypical_PIKK_ATM_ATM_ST	Q13315	ATM	Q13315	ATM	S2996	N3003S	3003	Missense	distal	7	no	11.474	11.459	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	9.540	Down-regulation
Atypical_PIKK_ATM_ATM_ST	Q13315	ATM	Q13315	ATM	S2996	D2997G	2997	Missense	proximal	1	no	11.474	11.031	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	9.540	Down-regulation
Atypical_PIKK_ATM_ATM_ST	Q13315	ATM	Q13315	ATM	S2996	L2995I	2995	Missense	proximal	-1	no	11.474	11.388	EPSD;PhosphoSitePlus	TCGA;ICGC	9.540	Down-regulation
Atypical_PIKK_ATM_ATM_ST	Q8N680	ZBTB2	Q13315	ATM	S115	A114T	114	Missense	proximal	-1	no	13.086	13.257	PhosphoSitePlus	TCGA;ICGC;COSMIC	9.540	Up-regulation
Atypical_PIKK_ATM_ATM_ST	Q8N680	ZBTB2	Q13315	ATM	S115	A114G	114	Missense	proximal	-1	no	13.086	13.055	PhosphoSitePlus	TCGA;ICGC;COSMIC	9.540	Down-regulation
Atypical_PIKK_ATM_ATM_ST	Q8N680	ZBTB2	Q13315	ATM	S115	S120C	120	Missense	distal	5	no	13.086	13.312	PhosphoSitePlus	TCGA;ICGC;COSMIC	9.540	Up-regulation
Atypical_PIKK_ATM_ATM_ST	Q8N680	ZBTB2	Q13315	ATM	S115	S115R	115	Missense	central	0	yes	13.086	0.000	PhosphoSitePlus	TCGA;ICGC;COSMIC	9.540	Loss
Atypical_PIKK_ATM_ATM_ST	Q8N680	ZBTB2	Q13315	ATM	S167	E169K	169	Missense	proximal	2	no	14.026	12.695	EPSD	TCGA;ICGC;COSMIC	9.540	Down-regulation
Atypical_PIKK_ATM_ATM_ST	Q8N680	ZBTB2	Q13315	ATM	S167	Q170H	170	Missense	distal	3	no	14.026	14.166	EPSD	TCGA;ICGC;COSMIC;GDSC;CCLE	9.540	Up-regulation
Atypical_PIKK_ATM_ATM_ST	Q8N680	ZBTB2	Q13315	ATM	S167	R160L	160	Missense	distal	-7	no	14.026	13.837	EPSD	TCGA;ICGC;COSMIC	9.540	Down-regulation
Atypical_PIKK_ATM_ATM_ST	Q8N680	ZBTB2	Q13315	ATM	S175	E169K	169	Missense	distal	-6	no	14.269	13.968	EPSD	TCGA;ICGC;COSMIC	9.540	Down-regulation
Atypical_PIKK_ATM_ATM_ST	Q8N680	ZBTB2	Q13315	ATM	S175	Q170H	170	Missense	distal	-5	no	14.269	14.451	EPSD	TCGA;ICGC;COSMIC;GDSC;CCLE	9.540	Up-regulation
Atypical_PIKK_ATM_ATM_ST	Q8N680	ZBTB2	Q13315	ATM	S175	Q176H	176	Missense	proximal	1	no	14.269	-0.640	EPSD	TCGA;ICGC;COSMIC	9.540	Loss
Atypical_PIKK_ATM_ATM_ST	Q8N680	ZBTB2	Q13315	ATM	S178	Q176H	176	Missense	proximal	-2	no	13.761	13.458	EPSD	TCGA;ICGC;COSMIC	9.540	Down-regulation
Atypical_PIKK_ATM_ATM_ST	Q8N680	ZBTB2	Q13315	ATM	S178	A185T	185	Missense	distal	7	no	13.761	13.747	EPSD	TCGA;ICGC;COSMIC	9.540	Down-regulation
Atypical_PIKK_ATM_ATM_ST	Q8N680	ZBTB2	Q13315	ATM	S203	P210R	210	Missense	distal	7	no	10.550	10.566	EPSD	TCGA;ICGC;COSMIC	9.540	Up-regulation
Atypical_PIKK_ATM_ATM_ST	Q8N680	ZBTB2	Q13315	ATM	S203	S201L	201	Missense	proximal	-2	no	10.550	10.160	EPSD	TCGA;ICGC;COSMIC	9.540	Down-regulation
Atypical_PIKK_ATM_ATM_ST	Q8N680	ZBTB2	Q13315	ATM	S203	E205D	205	Missense	proximal	2	no	10.550	10.419	EPSD	TCGA;ICGC	9.540	Down-regulation
Atypical_PIKK_ATM_ATM_ST	Q8N680	ZBTB2	Q13315	ATM	S284	R290C	290	Missense	distal	6	no	15.839	15.784	EPSD	TCGA;ICGC	9.540	Down-regulation
Atypical_PIKK_ATM_ATM_ST	Q8N680	ZBTB2	Q13315	ATM	S284	T277I	277	Missense	distal	-7	no	15.839	15.256	EPSD	TCGA;ICGC;COSMIC	9.540	Down-regulation
Atypical_PIKK_ATM_ATM_ST	Q8N680	ZBTB2	Q13315	ATM	S435	M440L	440	Missense	distal	5	no	13.573	13.552	EPSD	TCGA;ICGC;COSMIC	9.540	Down-regulation
Atypical_PIKK_ATM_ATM_ST	Q7L7X3	TAOK1	Q13315	ATM	S177	M175I	175	Missense	proximal	-2	no	10.261	10.010	EPSD	TCGA	9.540	Down-regulation
Atypical_PIKK_ATM_ATM_ST	Q7L7X3	TAOK1	Q13315	ATM	S177	P178T	178	Missense	proximal	1	no	10.261	5.254	EPSD	TCGA;ICGC;COSMIC	9.540	Loss
Atypical_PIKK_ATM_ATM_ST	Q7L7X3	TAOK1	Q13315	ATM	S421	D418N	418	Missense	distal	-3	no	11.232	10.959	EPSD	TCGA;ICGC;COSMIC	9.540	Down-regulation
Atypical_PIKK_ATM_ATM_ST	Q7L7X3	TAOK1	Q13315	ATM	S421	R427H	427	Missense	distal	6	no	11.232	11.216	EPSD	TCGA;ICGC	9.540	Down-regulation
Atypical_PIKK_ATM_ATM_ST	Q7L7X3	TAOK1	Q13315	ATM	T502	L496S	496	Missense	distal	-6	no	11.045	11.333	EPSD	TCGA;ICGC;COSMIC	9.540	Up-regulation
Atypical_PIKK_ATM_ATM_ST	Q7L7X3	TAOK1	Q13315	ATM	T643	E648Q	648	Missense	distal	5	no	12.581	12.806	PhosphoSitePlus;EPSD	TCGA;ICGC	9.540	Up-regulation
Atypical_PIKK_ATM_ATM_ST	Q7L7X3	TAOK1	Q13315	ATM	T643	Q642R	642	Missense	proximal	-1	no	12.581	12.274	PhosphoSitePlus;EPSD	TCGA;ICGC;COSMIC	9.540	Down-regulation
Atypical_PIKK_ATM_ATM_ST	Q7L7X3	TAOK1	Q13315	ATM	T643	A650V	650	Missense	distal	7	no	12.581	12.599	PhosphoSitePlus;EPSD	TCGA;ICGC;COSMIC	9.540	Up-regulation
Atypical_PIKK_ATM_ATM_ST	Q7L7X3	TAOK1	Q13315	ATM	T643	E637G	637	Missense	distal	-6	no	12.581	12.192	PhosphoSitePlus;EPSD	TCGA;ICGC	9.540	Down-regulation
Atypical_PIKK_ATM_ATM_ST	Q7L7X3	TAOK1	Q13315	ATM	S965	Q967E	967	Missense	proximal	2	no	9.076	9.889	EPSD	TCGA;ICGC;COSMIC	9.540	Gain
Atypical_PIKK_ATM_ATM_ST	P04637	TP53	Q13315	ATM	S46	D48N	48	Missense	proximal	2	no	12.775	11.753	PhosphoSitePlus;EPSD	TCGA;ICGC;COSMIC;GDSC;CCLE	9.540	Down-regulation
Atypical_PIKK_ATM_ATM_ST	P04637	TP53	Q13315	ATM	S99	G105C	105	Missense	distal	6	no	12.537	12.483	EPSD	TCGA;ICGC;COSMIC;GDSC	9.540	Down-regulation
Atypical_PIKK_ATM_ATM_ST	P04637	TP53	Q13315	ATM	S99	S106R	106	Missense	distal	7	no	12.537	12.571	EPSD	TCGA;ICGC;COSMIC;GDSC;CCLE	9.540	Up-regulation
Atypical_PIKK_ATM_ATM_ST	P04637	TP53	Q13315	ATM	S99	G105R	105	Missense	distal	6	no	12.537	12.538	EPSD	TCGA;ICGC;COSMIC;CCLE	9.540	Up-regulation
Atypical_PIKK_ATM_ATM_ST	P04637	TP53	Q13315	ATM	S99	G105V	105	Missense	distal	6	no	12.537	12.531	EPSD	TCGA;ICGC;COSMIC	9.540	Down-regulation
Atypical_PIKK_ATM_ATM_ST	P04637	TP53	Q13315	ATM	S99	G105D	105	Missense	distal	6	no	12.537	12.533	EPSD	TCGA;ICGC;COSMIC	9.540	Down-regulation
Atypical_PIKK_ATM_ATM_ST	P04637	TP53	Q13315	ATM	S99	G105S	105	Missense	distal	6	no	12.537	12.555	EPSD	TCGA;ICGC;COSMIC	9.540	Up-regulation
Atypical_PIKK_ATM_ATM_ST	P04637	TP53	Q13315	ATM	S99	V97D	97	Missense	proximal	-2	no	12.537	12.903	EPSD	TCGA;ICGC;COSMIC	9.540	Up-regulation
Atypical_PIKK_ATM_ATM_ST	P04637	TP53	Q13315	ATM	S99	P92S	92	Missense	distal	-7	no	12.537	12.773	EPSD	TCGA;ICGC	9.540	Up-regulation
Atypical_PIKK_ATM_ATM_ST	P04637	TP53	Q13315	ATM	S106	G105C	105	Missense	proximal	-1	no	10.952	10.944	EPSD	TCGA;ICGC;COSMIC;GDSC	9.540	Down-regulation
Atypical_PIKK_ATM_ATM_ST	P04637	TP53	Q13315	ATM	S106	R110L	110	Missense	distal	4	no	10.952	11.112	EPSD	TCGA;ICGC;COSMIC;GDSC;CCLE	9.540	Up-regulation
Atypical_PIKK_ATM_ATM_ST	P04637	TP53	Q13315	ATM	S106	L111R	111	Missense	distal	5	no	10.952	10.953	EPSD	TCGA;ICGC;COSMIC	9.540	Up-regulation
Atypical_PIKK_ATM_ATM_ST	P04637	TP53	Q13315	ATM	S106	L111P	111	Missense	distal	5	no	10.952	10.970	EPSD	TCGA;ICGC;COSMIC	9.540	Up-regulation
Atypical_PIKK_ATM_ATM_ST	P04637	TP53	Q13315	ATM	S106	L111Q	111	Missense	distal	5	no	10.952	10.841	EPSD	TCGA;ICGC;COSMIC	9.540	Down-regulation
Atypical_PIKK_ATM_ATM_ST	P04637	TP53	Q13315	ATM	S106	Y107D	107	Missense	proximal	1	no	10.952	10.637	EPSD	TCGA;ICGC;COSMIC	9.540	Down-regulation
Atypical_PIKK_ATM_ATM_ST	P04637	TP53	Q13315	ATM	S106	F113C	113	Missense	distal	7	no	10.952	10.945	EPSD	TCGA;ICGC;COSMIC;GDSC;CCLE	9.540	Down-regulation
Atypical_PIKK_ATM_ATM_ST	P04637	TP53	Q13315	ATM	S106	F113V	113	Missense	distal	7	no	10.952	10.941	EPSD	TCGA;ICGC;COSMIC;GDSC;CCLE	9.540	Down-regulation
Atypical_PIKK_ATM_ATM_ST	P04637	TP53	Q13315	ATM	S106	R110C	110	Missense	distal	4	no	10.952	11.280	EPSD	TCGA;ICGC;COSMIC;GDSC;CCLE	9.540	Up-regulation
Atypical_PIKK_ATM_ATM_ST	P04637	TP53	Q13315	ATM	S106	S106R	106	Missense	central	0	yes	10.952	0.000	EPSD	TCGA;ICGC;COSMIC;GDSC;CCLE	9.540	Loss
Atypical_PIKK_ATM_ATM_ST	P04637	TP53	Q13315	ATM	S106	F109S	109	Missense	distal	3	no	10.952	10.371	EPSD	TCGA;ICGC;COSMIC	9.540	Down-regulation
Atypical_PIKK_ATM_ATM_ST	P04637	TP53	Q13315	ATM	S106	G105R	105	Missense	proximal	-1	no	10.952	10.770	EPSD	TCGA;ICGC;COSMIC;CCLE	9.540	Down-regulation
Atypical_PIKK_ATM_ATM_ST	P04637	TP53	Q13315	ATM	S106	G105V	105	Missense	proximal	-1	no	10.952	10.721	EPSD	TCGA;ICGC;COSMIC	9.540	Down-regulation
Atypical_PIKK_ATM_ATM_ST	P04637	TP53	Q13315	ATM	S106	F109V	109	Missense	distal	3	no	10.952	10.714	EPSD	TCGA;ICGC;COSMIC	9.540	Down-regulation
Atypical_PIKK_ATM_ATM_ST	P04637	TP53	Q13315	ATM	S106	R110P	110	Missense	distal	4	no	10.952	10.893	EPSD	TCGA;ICGC;COSMIC;GDSC;CCLE	9.540	Down-regulation
Atypical_PIKK_ATM_ATM_ST	P04637	TP53	Q13315	ATM	S106	G105D	105	Missense	proximal	-1	no	10.952	11.090	EPSD	TCGA;ICGC;COSMIC	9.540	Up-regulation
Atypical_PIKK_ATM_ATM_ST	P04637	TP53	Q13315	ATM	S106	F109C	109	Missense	distal	3	no	10.952	10.792	EPSD	TCGA;ICGC;COSMIC	9.540	Down-regulation
Atypical_PIKK_ATM_ATM_ST	P04637	TP53	Q13315	ATM	S106	G105S	105	Missense	proximal	-1	no	10.952	11.144	EPSD	TCGA;ICGC;COSMIC	9.540	Up-regulation
Atypical_PIKK_ATM_ATM_ST	P04637	TP53	Q13315	ATM	S106	G108S	108	Missense	proximal	2	no	10.952	11.811	EPSD	TCGA;ICGC;COSMIC	9.540	Up-regulation
Atypical_PIKK_ATM_ATM_ST	P04637	TP53	Q13315	ATM	S106	F113L	113	Missense	distal	7	no	10.952	10.912	EPSD	TCGA;ICGC;COSMIC;GDSC;CCLE	9.540	Down-regulation
Atypical_PIKK_ATM_ATM_ST	P04637	TP53	Q13315	ATM	S127	K132N	132	Missense	distal	5	no	9.567	9.538	EPSD	TCGA;ICGC;COSMIC;GDSC;CCLE	9.540	Loss
Atypical_PIKK_ATM_ATM_ST	P04637	TP53	Q13315	ATM	S127	S121Y	121	Missense	distal	-6	no	9.567	9.317	EPSD	TCGA;ICGC;COSMIC	9.540	Loss
Atypical_PIKK_ATM_ATM_ST	P04637	TP53	Q13315	ATM	S127	M133K	133	Missense	distal	6	no	9.567	9.575	EPSD	TCGA;ICGC;COSMIC;CCLE	9.540	Up-regulation
Atypical_PIKK_ATM_ATM_ST	P04637	TP53	Q13315	ATM	S127	K132E	132	Missense	distal	5	no	9.567	9.392	EPSD	TCGA;ICGC;COSMIC;GDSC;CCLE	9.540	Loss
Atypical_PIKK_ATM_ATM_ST	P04637	TP53	Q13315	ATM	S127	Y126C	126	Missense	proximal	-1	no	9.567	9.416	EPSD	TCGA;ICGC;COSMIC;GDSC	9.540	Loss
Atypical_PIKK_ATM_ATM_ST	P04637	TP53	Q13315	ATM	S127	S127P	127	Missense	central	0	yes	9.567	0.000	EPSD	TCGA;ICGC;COSMIC;GDSC;CCLE	9.540	Loss
Atypical_PIKK_ATM_ATM_ST	P04637	TP53	Q13315	ATM	S127	Y126N	126	Missense	proximal	-1	no	9.567	9.560	EPSD	TCGA;ICGC;COSMIC	9.540	Down-regulation
Atypical_PIKK_ATM_ATM_ST	P04637	TP53	Q13315	ATM	S127	L130V	130	Missense	distal	3	no	9.567	9.628	EPSD	TCGA;ICGC;COSMIC;GDSC;CCLE	9.540	Up-regulation
Atypical_PIKK_ATM_ATM_ST	P04637	TP53	Q13315	ATM	S127	K132T	132	Missense	distal	5	no	9.567	9.546	EPSD	TCGA;ICGC;COSMIC;GDSC;CCLE	9.540	Down-regulation
Atypical_PIKK_ATM_ATM_ST	P04637	TP53	Q13315	ATM	S127	S127Y	127	Missense	central	0	yes	9.567	0.000	EPSD	TCGA;ICGC;COSMIC	9.540	Loss
Atypical_PIKK_ATM_ATM_ST	P04637	TP53	Q13315	ATM	S127	S127F	127	Missense	central	0	yes	9.567	0.000	EPSD	TCGA;ICGC;COSMIC;CCLE	9.540	Loss
Atypical_PIKK_ATM_ATM_ST	P04637	TP53	Q13315	ATM	S127	M133R	133	Missense	distal	6	no	9.567	9.578	EPSD	TCGA;ICGC;COSMIC	9.540	Up-regulation
Atypical_PIKK_ATM_ATM_ST	P04637	TP53	Q13315	ATM	S127	K132R	132	Missense	distal	5	no	9.567	9.728	EPSD	TCGA;ICGC;COSMIC;GDSC;CCLE	9.540	Up-regulation
Atypical_PIKK_ATM_ATM_ST	P04637	TP53	Q13315	ATM	S127	F134L	134	Missense	distal	7	no	9.567	9.526	EPSD	TCGA;ICGC;COSMIC;CCLE	9.540	Loss
Atypical_PIKK_ATM_ATM_ST	P04637	TP53	Q13315	ATM	S127	Y126S	126	Missense	proximal	-1	no	9.567	9.615	EPSD	TCGA;ICGC;COSMIC	9.540	Up-regulation
Atypical_PIKK_ATM_ATM_ST	P04637	TP53	Q13315	ATM	S127	L130P	130	Missense	distal	3	no	9.567	9.437	EPSD	TCGA;ICGC;COSMIC	9.540	Loss
Atypical_PIKK_ATM_ATM_ST	P04637	TP53	Q13315	ATM	S127	L130F	130	Missense	distal	3	no	9.567	9.867	EPSD	TCGA;ICGC;COSMIC;CCLE	9.540	Up-regulation
Atypical_PIKK_ATM_ATM_ST	P04637	TP53	Q13315	ATM	S127	F134V	134	Missense	distal	7	no	9.567	9.555	EPSD	TCGA;ICGC;COSMIC	9.540	Down-regulation
Atypical_PIKK_ATM_ATM_ST	P04637	TP53	Q13315	ATM	S127	T125M	125	Missense	proximal	-2	no	9.567	9.216	EPSD	TCGA;ICGC;COSMIC;GDSC	9.540	Loss
Atypical_PIKK_ATM_ATM_ST	P04637	TP53	Q13315	ATM	S127	Y126D	126	Missense	proximal	-1	no	9.567	9.561	EPSD	TCGA;ICGC;COSMIC;GDSC	9.540	Down-regulation
Atypical_PIKK_ATM_ATM_ST	P04637	TP53	Q13315	ATM	S127	K120E	120	Missense	distal	-7	no	9.567	10.235	EPSD	TCGA;ICGC;COSMIC	9.540	Up-regulation
Atypical_PIKK_ATM_ATM_ST	P04637	TP53	Q13315	ATM	S127	N131S	131	Missense	distal	4	no	9.567	9.440	EPSD	TCGA;ICGC;COSMIC	9.540	Loss
Atypical_PIKK_ATM_ATM_ST	P04637	TP53	Q13315	ATM	S127	T125P	125	Missense	proximal	-2	no	9.567	9.418	EPSD	TCGA;ICGC;COSMIC;CCLE	9.540	Loss
Atypical_PIKK_ATM_ATM_ST	P04637	TP53	Q13315	ATM	S127	S127C	127	Missense	central	0	yes	9.567	0.000	EPSD	TCGA;ICGC;COSMIC;CCLE	9.540	Loss
Atypical_PIKK_ATM_ATM_ST	P04637	TP53	Q13315	ATM	S127	N131I	131	Missense	distal	4	no	9.567	10.103	EPSD	TCGA;ICGC;COSMIC	9.540	Up-regulation
Atypical_PIKK_ATM_ATM_ST	P04637	TP53	Q13315	ATM	S127	Y126H	126	Missense	proximal	-1	no	9.567	9.411	EPSD	TCGA;ICGC;COSMIC;GDSC	9.540	Loss
Atypical_PIKK_ATM_ATM_ST	P04637	TP53	Q13315	ATM	S127	K132Q	132	Missense	distal	5	no	9.567	9.616	EPSD	TCGA;ICGC;COSMIC;GDSC;CCLE	9.540	Up-regulation
Atypical_PIKK_ATM_ATM_ST	P04637	TP53	Q13315	ATM	S127	L130R	130	Missense	distal	3	no	9.567	9.470	EPSD	TCGA;ICGC;COSMIC;CCLE	9.540	Loss
Atypical_PIKK_ATM_ATM_ST	P04637	TP53	Q13315	ATM	S183	C176S	176	Missense	distal	-7	no	9.068	9.741	EPSD	TCGA;ICGC;COSMIC;GDSC;CCLE	9.540	Gain
Atypical_PIKK_ATM_ATM_ST	P04637	TP53	Q13315	ATM	S183	H179D	179	Missense	distal	-4	no	9.068	9.743	EPSD	TCGA;ICGC;COSMIC;GDSC;CCLE	9.540	Gain
Atypical_PIKK_ATM_ATM_ST	P04637	TP53	Q13315	ATM	S269	F270L	270	Missense	proximal	1	no	5.967	9.848	EPSD	TCGA;ICGC;COSMIC	9.540	Gain
Atypical_PIKK_ATM_ATM_ST	P04637	TP53	Q13315	ATM	T284	E285Q	285	Missense	proximal	1	no	7.253	13.149	EPSD	TCGA;ICGC;COSMIC	9.540	Gain
Atypical_PIKK_ATM_ATM_ST	Q9H3D4	TP63	Q13315	ATM	S51	I58T	58	Missense	distal	7	no	11.008	10.993	EPSD	TCGA;ICGC;COSMIC	9.540	Down-regulation
Atypical_PIKK_ATM_ATM_ST	Q9H3D4	TP63	Q13315	ATM	S51	E53Q	53	Missense	proximal	2	no	11.008	10.195	EPSD	TCGA;ICGC;COSMIC	9.540	Down-regulation
Atypical_PIKK_ATM_ATM_ST	Q9H3D4	TP63	Q13315	ATM	S162	P166L	166	Missense	distal	4	no	9.666	9.885	EPSD	TCGA;ICGC;COSMIC	9.540	Up-regulation
Atypical_PIKK_ATM_ATM_ST	Q9H3D4	TP63	Q13315	ATM	S162	A164T	164	Missense	proximal	2	no	9.666	9.987	EPSD	TCGA;COSMIC	9.540	Up-regulation
Atypical_PIKK_ATM_ATM_ST	Q9H3D4	TP63	Q13315	ATM	S162	A164V	164	Missense	proximal	2	no	9.666	9.357	EPSD	TCGA;ICGC;COSMIC	9.540	Loss
Atypical_PIKK_ATM_ATM_ST	Q9H3D4	TP63	Q13315	ATM	S162	P163L	163	Missense	proximal	1	no	9.666	8.112	EPSD	TCGA;ICGC;COSMIC	9.540	Loss
Atypical_PIKK_ATM_ATM_ST	Q9H3D4	TP63	Q13315	ATM	S162	D157Y	157	Missense	distal	-5	no	9.666	9.901	EPSD	TCGA;ICGC;COSMIC	9.540	Up-regulation
Atypical_PIKK_ATM_ATM_ST	Q9H3D4	TP63	Q13315	ATM	S455	S458L	458	Missense	distal	3	no	10.300	10.582	EPSD	TCGA;COSMIC	9.540	Up-regulation
Atypical_PIKK_ATM_ATM_ST	Q9H3D4	TP63	Q13315	ATM	S455	P456L	456	Missense	proximal	1	no	10.300	8.745	EPSD	TCGA;COSMIC	9.540	Loss
Atypical_PIKK_ATM_ATM_ST	Q9H3D4	TP63	Q13315	ATM	S479	N483S	483	Missense	distal	4	no	15.147	15.020	PhosphoSitePlus	TCGA;COSMIC	9.540	Down-regulation
Atypical_PIKK_ATM_ATM_ST	Q9H3D4	TP63	Q13315	ATM	S479	L481P	481	Missense	proximal	2	no	15.147	15.936	PhosphoSitePlus	TCGA;COSMIC	9.540	Up-regulation
Atypical_PIKK_ATM_ATM_ST	Q9H3D4	TP63	Q13315	ATM	S479	M472T	472	Missense	distal	-7	no	15.147	15.541	PhosphoSitePlus	TCGA;COSMIC	9.540	Up-regulation
Atypical_PIKK_ATM_ATM_ST	P27707	DCK	Q13315	ATM	T64	E69K	69	Missense	distal	5	no	13.775	13.950	EPSD	TCGA;ICGC;COSMIC	9.540	Up-regulation
Atypical_PIKK_ATM_ATM_ST	P27707	DCK	Q13315	ATM	T64	D66Y	66	Missense	proximal	2	no	13.775	12.535	EPSD	TCGA;ICGC	9.540	Down-regulation
Atypical_PIKK_ATM_ATM_ST	P27707	DCK	Q13315	ATM	S74	E69K	69	Missense	distal	-5	no	16.242	16.324	PhosphoSitePlus	TCGA;ICGC;COSMIC	9.540	Up-regulation
Atypical_PIKK_ATM_ATM_ST	O15111	CHUK	Q13315	ATM	T23	R18W	18	Missense	distal	-5	no	9.451	9.617	EPSD	TCGA;ICGC;COSMIC	9.540	Gain
Atypical_PIKK_ATM_ATM_ST	O15111	CHUK	Q13315	ATM	S119	E118Q	118	Missense	proximal	-1	no	12.307	12.030	EPSD	TCGA;ICGC;COSMIC	9.540	Down-regulation
Atypical_PIKK_ATM_ATM_ST	O15111	CHUK	Q13315	ATM	S119	S123Y	123	Missense	distal	4	no	12.307	12.610	EPSD	TCGA;ICGC;COSMIC	9.540	Up-regulation
Atypical_PIKK_ATM_ATM_ST	O15111	CHUK	Q13315	ATM	S473	L480V	480	Missense	distal	7	no	13.086	13.115	PhosphoSitePlus	TCGA;ICGC;COSMIC	9.540	Up-regulation
Atypical_PIKK_ATM_ATM_ST	O15111	CHUK	Q13315	ATM	S473	N467S	467	Missense	distal	-6	no	13.086	13.202	PhosphoSitePlus	TCGA;ICGC;COSMIC	9.540	Up-regulation
Atypical_PIKK_ATM_ATM_ST	Q9BUR4	WRAP53	Q13315	ATM	T6	E5K	5	Missense	proximal	-1	no	10.869	10.467	EPSD	TCGA;ICGC;COSMIC	9.540	Down-regulation
Atypical_PIKK_ATM_ATM_ST	Q9BUR4	WRAP53	Q13315	ATM	S54	R52W	52	Missense	proximal	-2	no	10.205	10.154	EPSD	TCGA;ICGC;COSMIC	9.540	Down-regulation
Atypical_PIKK_ATM_ATM_ST	Q9BUR4	WRAP53	Q13315	ATM	S54	P50S	50	Missense	distal	-4	no	10.205	10.874	EPSD	TCGA;ICGC;COSMIC	9.540	Up-regulation
Atypical_PIKK_ATM_ATM_ST	Q9BUR4	WRAP53	Q13315	ATM	S64	E66K	66	Missense	proximal	2	no	15.675	14.345	PhosphoSitePlus	TCGA;ICGC;COSMIC	9.540	Down-regulation
Atypical_PIKK_ATM_ATM_ST	Q8IX03	WWC1	Q13315	ATM	S255	H256Y	256	Missense	proximal	1	no	0.580	9.773	EPSD	TCGA;ICGC;COSMIC	9.540	Gain
Atypical_PIKK_ATM_ATM_ST	Q8IX03	WWC1	Q13315	ATM	S268	S269L	269	Missense	proximal	1	no	4.556	9.977	EPSD	TCGA;ICGC;COSMIC	9.540	Gain
Atypical_PIKK_ATM_ATM_ST	Q8IX03	WWC1	Q13315	ATM	S445	R446Q	446	Missense	proximal	1	no	8.604	15.255	EPSD	TCGA;ICGC;COSMIC	9.540	Gain
Atypical_PIKK_ATM_ATM_ST	Q8IX03	WWC1	Q13315	ATM	S539	R537C	537	Missense	proximal	-2	no	9.723	9.704	EPSD	TCGA;ICGC;COSMIC	9.540	Down-regulation
Atypical_PIKK_ATM_ATM_ST	Q8IX03	WWC1	Q13315	ATM	S539	L540F	540	Missense	proximal	1	no	9.723	5.842	EPSD	TCGA;ICGC;COSMIC	9.540	Loss
Atypical_PIKK_ATM_ATM_ST	Q8IX03	WWC1	Q13315	ATM	S539	P536S	536	Missense	distal	-3	no	9.723	9.527	EPSD	TCGA;ICGC;COSMIC	9.540	Loss
Atypical_PIKK_ATM_ATM_ST	Q8IX03	WWC1	Q13315	ATM	S539	S533F	533	Missense	distal	-6	no	9.723	9.192	EPSD	TCGA;ICGC;COSMIC	9.540	Loss
Atypical_PIKK_ATM_ATM_ST	Q8IX03	WWC1	Q13315	ATM	S542	R537C	537	Missense	distal	-5	no	10.585	10.602	EPSD	TCGA;ICGC;COSMIC	9.540	Up-regulation
Atypical_PIKK_ATM_ATM_ST	Q8IX03	WWC1	Q13315	ATM	S542	L540F	540	Missense	proximal	-2	no	10.585	10.074	EPSD	TCGA;ICGC;COSMIC	9.540	Down-regulation
Atypical_PIKK_ATM_ATM_ST	Q8IX03	WWC1	Q13315	ATM	S542	S548F	548	Missense	distal	6	no	10.585	10.509	EPSD	TCGA;ICGC;COSMIC	9.540	Down-regulation
Atypical_PIKK_ATM_ATM_ST	Q8IX03	WWC1	Q13315	ATM	S542	P536S	536	Missense	distal	-6	no	10.585	10.644	EPSD	TCGA;ICGC;COSMIC	9.540	Up-regulation
Atypical_PIKK_ATM_ATM_ST	Q8IX03	WWC1	Q13315	ATM	T596	E597Q	597	Missense	proximal	1	no	7.948	13.845	EPSD	TCGA;ICGC;COSMIC	9.540	Gain
Atypical_PIKK_ATM_ATM_ST	Q8IX03	WWC1	Q13315	ATM	T660	R661Q	661	Missense	proximal	1	no	8.063	14.715	EPSD	TCGA;ICGC;COSMIC	9.540	Gain
Atypical_PIKK_ATM_ATM_ST	Q8IX03	WWC1	Q13315	ATM	S785	R779C	779	Missense	distal	-6	no	11.492	11.293	EPSD	TCGA;ICGC;COSMIC	9.540	Down-regulation
Atypical_PIKK_ATM_ATM_ST	Q8IX03	WWC1	Q13315	ATM	S876	A875D	875	Missense	proximal	-1	no	12.923	13.029	EPSD	TCGA;ICGC	9.540	Up-regulation
Atypical_PIKK_ATM_ATM_ST	Q8IX03	WWC1	Q13315	ATM	S899	P898S	898	Missense	proximal	-1	no	9.300	9.592	EPSD	TCGA;ICGC;COSMIC	9.540	Gain
Atypical_PIKK_ATM_ATM_ST	Q8IX03	WWC1	Q13315	ATM	S914	R920L	920	Missense	distal	6	no	15.951	15.913	EPSD	TCGA;ICGC;COSMIC	9.540	Down-regulation
Atypical_PIKK_ATM_ATM_ST	Q8IX03	WWC1	Q13315	ATM	S914	S914F	914	Missense	central	0	yes	15.951	0.000	EPSD	TCGA;ICGC;COSMIC	9.540	Loss
Atypical_PIKK_ATM_ATM_ST	Q8IX03	WWC1	Q13315	ATM	S914	P913L	913	Missense	proximal	-1	no	15.951	16.108	EPSD	TCGA	9.540	Up-regulation
Atypical_PIKK_ATM_ATM_ST	Q8IX03	WWC1	Q13315	ATM	S931	F930S	930	Missense	proximal	-1	no	9.211	9.637	EPSD	TCGA;ICGC;COSMIC	9.540	Gain
Atypical_PIKK_ATM_ATM_ST	Q8IX03	WWC1	Q13315	ATM	S936	Q937K	937	Missense	proximal	1	no	13.378	6.529	EPSD	TCGA;ICGC;COSMIC	9.540	Loss
Atypical_PIKK_ATM_ATM_ST	Q8IX03	WWC1	Q13315	ATM	S936	V939L	939	Missense	distal	3	no	13.378	13.316	EPSD	TCGA;ICGC;COSMIC	9.540	Down-regulation
Atypical_PIKK_ATM_ATM_ST	Q8IX03	WWC1	Q13315	ATM	S936	S931F	931	Missense	distal	-5	no	13.378	13.701	EPSD	TCGA;ICGC;COSMIC	9.540	Up-regulation
Atypical_PIKK_ATM_ATM_ST	Q8IX03	WWC1	Q13315	ATM	S936	R941W	941	Missense	distal	5	no	13.378	13.402	EPSD	TCGA;ICGC;COSMIC	9.540	Up-regulation
Atypical_PIKK_ATM_ATM_ST	Q8IX03	WWC1	Q13315	ATM	S936	F930S	930	Missense	distal	-6	no	13.378	13.909	EPSD	TCGA;ICGC;COSMIC	9.540	Up-regulation
Atypical_PIKK_ATM_ATM_ST	P37275	ZEB1	Q13315	ATM	S167	L170S	170	Missense	distal	3	no	13.065	12.783	EPSD	TCGA;COSMIC	9.540	Down-regulation
Atypical_PIKK_ATM_ATM_ST	P37275	ZEB1	Q13315	ATM	T716	S713T	713	Missense	distal	-3	no	12.764	12.696	EPSD	TCGA;COSMIC	9.540	Down-regulation
Atypical_PIKK_ATM_ATM_ST	P37275	ZEB1	Q13315	ATM	T890	K895N	895	Missense	distal	5	no	9.705	9.676	EPSD	TCGA	9.540	Down-regulation
Atypical_PIKK_ATM_ATM_ST	P11166	SLC2A1	Q13315	ATM	S248	R249Q	249	Missense	proximal	1	no	9.392	16.043	EPSD	TCGA;ICGC	9.540	Gain
Atypical_PIKK_ATM_ATM_ST	P11166	SLC2A1	Q13315	ATM	S473	G466S	466	Missense	distal	-7	no	14.050	14.562	EPSD	TCGA;ICGC;COSMIC	9.540	Up-regulation
Atypical_PIKK_ATM_ATM_ST	P11166	SLC2A1	Q13315	ATM	S473	Q474K	474	Missense	proximal	1	no	14.050	7.202	EPSD	TCGA;ICGC;COSMIC	9.540	Loss
Atypical_PIKK_ATM_ATM_ST	P11166	SLC2A1	Q13315	ATM	T478	Q474K	474	Missense	distal	-4	no	9.834	9.586	EPSD	TCGA;ICGC;COSMIC	9.540	Down-regulation
Atypical_PIKK_ATM_ATM_ST	Q969R5	L3MBTL2	Q13315	ATM	T98	E100K	100	Missense	proximal	2	no	9.638	8.307	EPSD	TCGA;ICGC;COSMIC	9.540	Loss
Atypical_PIKK_ATM_ATM_ST	Q969R5	L3MBTL2	Q13315	ATM	T98	T98I	98	Missense	central	0	yes	9.638	0.000	EPSD	TCGA;ICGC;COSMIC	9.540	Loss
Atypical_PIKK_ATM_ATM_ST	Q969R5	L3MBTL2	Q13315	ATM	S117	R116S	116	Missense	proximal	-1	no	9.893	10.268	EPSD	TCGA;ICGC	9.540	Up-regulation
Atypical_PIKK_ATM_ATM_ST	Q969R5	L3MBTL2	Q13315	ATM	S221	D222N	222	Missense	proximal	1	no	11.280	7.449	EPSD	TCGA;ICGC;COSMIC	9.540	Loss
Atypical_PIKK_ATM_ATM_ST	Q969R5	L3MBTL2	Q13315	ATM	S335	R339H	339	Missense	distal	4	no	13.059	12.994	PhosphoSitePlus	TCGA;ICGC	9.540	Down-regulation
Atypical_PIKK_ATM_ATM_ST	Q969R5	L3MBTL2	Q13315	ATM	S335	R341C	341	Missense	distal	6	no	13.059	13.004	PhosphoSitePlus	TCGA;ICGC;COSMIC	9.540	Down-regulation
Atypical_PIKK_ATM_ATM_ST	Q969R5	L3MBTL2	Q13315	ATM	S661	S662L	662	Missense	proximal	1	no	4.378	9.798	EPSD	TCGA;ICGC;COSMIC	9.540	Gain
Atypical_PIKK_ATM_ATM_ST	Q969R5	L3MBTL2	Q13315	ATM	S683	E677Q	677	Missense	distal	-6	no	9.759	9.535	EPSD	TCGA;ICGC;COSMIC	9.540	Loss
Atypical_PIKK_ATM_ATM_ST	Q969R5	L3MBTL2	Q13315	ATM	S683	V681L	681	Missense	proximal	-2	no	9.759	10.034	EPSD	TCGA;ICGC;COSMIC	9.540	Up-regulation
Atypical_PIKK_ATM_ATM_ST	Q969R5	L3MBTL2	Q13315	ATM	S683	S683W	683	Missense	central	0	yes	9.759	0.000	EPSD	TCGA;ICGC;COSMIC	9.540	Loss
Atypical_PIKK_ATM_ATM_ST	Q969R5	L3MBTL2	Q13315	ATM	S683	A682T	682	Missense	proximal	-1	no	9.759	9.930	EPSD	TCGA;ICGC;COSMIC	9.540	Up-regulation
Atypical_PIKK_ATM_ATM_ST	Q969R5	L3MBTL2	Q13315	ATM	S683	K686E	686	Missense	distal	3	no	9.759	9.470	EPSD	TCGA;ICGC;COSMIC	9.540	Loss
Atypical_PIKK_ATM_ATM_ST	Q969R5	L3MBTL2	Q13315	ATM	S683	A687T	687	Missense	distal	4	no	9.759	10.194	EPSD	TCGA;ICGC;COSMIC	9.540	Up-regulation
Atypical_PIKK_ATM_ATM_ST	Q969R5	L3MBTL2	Q13315	ATM	S689	S683W	683	Missense	distal	-6	no	12.191	11.842	EPSD	TCGA;ICGC;COSMIC	9.540	Down-regulation
Atypical_PIKK_ATM_ATM_ST	Q969R5	L3MBTL2	Q13315	ATM	S689	V696L	696	Missense	distal	7	no	12.191	12.161	EPSD	TCGA;ICGC;COSMIC	9.540	Down-regulation
Atypical_PIKK_ATM_ATM_ST	Q969R5	L3MBTL2	Q13315	ATM	S689	A682T	682	Missense	distal	-7	no	12.191	12.206	EPSD	TCGA;ICGC;COSMIC	9.540	Up-regulation
Atypical_PIKK_ATM_ATM_ST	Q969R5	L3MBTL2	Q13315	ATM	S689	K686E	686	Missense	distal	-3	no	12.191	12.123	EPSD	TCGA;ICGC;COSMIC	9.540	Down-regulation
Atypical_PIKK_ATM_ATM_ST	Q969R5	L3MBTL2	Q13315	ATM	S689	A687T	687	Missense	proximal	-2	no	12.191	12.290	EPSD	TCGA;ICGC;COSMIC	9.540	Up-regulation
Atypical_PIKK_ATM_ATM_ST	Q969R5	L3MBTL2	Q13315	ATM	S695	V696L	696	Missense	proximal	1	no	4.615	11.253	EPSD	TCGA;ICGC;COSMIC	9.540	Gain
Atypical_PIKK_ATM_ATM_ST	Q969R5	L3MBTL2	Q13315	ATM	T703	V696L	696	Missense	distal	-7	no	9.580	9.473	EPSD	TCGA;ICGC;COSMIC	9.540	Loss
Atypical_PIKK_ATM_ATM_ST	Q9Y4E8	USP15	Q13315	ATM	S229	P227S	227	Missense	proximal	-2	no	9.671	9.908	EPSD	TCGA;ICGC;COSMIC	9.540	Up-regulation
Atypical_PIKK_ATM_ATM_ST	Q9Y4E8	USP15	Q13315	ATM	S277	N273S	273	Missense	distal	-4	no	9.341	10.269	EPSD	TCGA;COSMIC	9.540	Gain
Atypical_PIKK_ATM_ATM_ST	Q9Y4E8	USP15	Q13315	ATM	S579	Y580D	580	Missense	proximal	1	no	11.010	10.695	EPSD	TCGA	9.540	Down-regulation
Atypical_PIKK_ATM_ATM_ST	Q9Y4E8	USP15	Q13315	ATM	T602	L609I	609	Missense	distal	7	no	10.156	10.168	EPSD	TCGA;COSMIC	9.540	Up-regulation
Atypical_PIKK_ATM_ATM_ST	Q9Y4E8	USP15	Q13315	ATM	S630	E623K	623	Missense	distal	-7	no	10.181	9.512	EPSD	TCGA;COSMIC	9.540	Loss
Atypical_PIKK_ATM_ATM_ST	Q9Y4E8	USP15	Q13315	ATM	S678	V684G	684	Missense	distal	6	no	16.513	16.518	PhosphoSitePlus	TCGA;COSMIC	9.540	Up-regulation
Atypical_PIKK_ATM_ATM_ST	Q9Y4E8	USP15	Q13315	ATM	S678	P672S	672	Missense	distal	-6	no	16.513	16.572	PhosphoSitePlus	TCGA;COSMIC	9.540	Up-regulation
Atypical_PIKK_ATM_ATM_ST	Q9Y4E8	USP15	Q13315	ATM	S678	P672L	672	Missense	distal	-6	no	16.513	16.284	PhosphoSitePlus	TCGA;COSMIC	9.540	Down-regulation
Atypical_PIKK_ATM_ATM_ST	Q9Y4E8	USP15	Q13315	ATM	S678	G685E	685	Missense	distal	7	no	16.513	16.468	PhosphoSitePlus	TCGA;COSMIC	9.540	Down-regulation
Atypical_PIKK_ATM_ATM_ST	Q9Y4E8	USP15	Q13315	ATM	S678	S683L	683	Missense	distal	5	no	16.513	16.677	PhosphoSitePlus	TCGA;COSMIC	9.540	Up-regulation
Atypical_PIKK_ATM_ATM_ST	Q9Y4E8	USP15	Q13315	ATM	S961	E963K	963	Missense	proximal	2	no	11.302	9.971	EPSD	TCGA;COSMIC	9.540	Down-regulation
Atypical_PIKK_ATM_ATM_ST	Q9Y4E8	USP15	Q13315	ATM	S961	D967H	967	Missense	distal	6	no	11.302	11.291	EPSD	TCGA;ICGC;COSMIC	9.540	Down-regulation
Atypical_PIKK_ATM_ATM_ST	Q8IW19	APLF	Q13315	ATM	S116	D122N	122	Missense	distal	6	no	15.476	15.488	PhosphoSitePlus	TCGA;ICGC;COSMIC	9.540	Up-regulation
Atypical_PIKK_ATM_ATM_ST	Q8IW19	APLF	Q13315	ATM	S116	D122Y	122	Missense	distal	6	no	15.476	15.457	PhosphoSitePlus	TCGA;ICGC;COSMIC	9.540	Down-regulation
Atypical_PIKK_ATM_ATM_ST	Q8IW19	APLF	Q13315	ATM	S144	G148R	148	Missense	distal	4	no	11.874	11.927	EPSD	TCGA;ICGC;COSMIC	9.540	Up-regulation
Atypical_PIKK_ATM_ATM_ST	Q8IW19	APLF	Q13315	ATM	S144	E139G	139	Missense	distal	-5	no	11.874	12.094	EPSD	TCGA;ICGC;COSMIC	9.540	Up-regulation
Atypical_PIKK_ATM_ATM_ST	Q8IW19	APLF	Q13315	ATM	T155	G148R	148	Missense	distal	-7	no	12.830	12.944	EPSD	TCGA;ICGC;COSMIC	9.540	Up-regulation
Atypical_PIKK_ATM_ATM_ST	Q9Y2K7	KDM2A	Q13315	ATM	S11	R9C	9	Missense	proximal	-2	no	15.759	15.740	EPSD	TCGA;ICGC;COSMIC	9.540	Down-regulation
Atypical_PIKK_ATM_ATM_ST	Q9Y2K7	KDM2A	Q13315	ATM	T115	K117T	117	Missense	proximal	2	no	11.997	12.555	EPSD	TCGA;ICGC;COSMIC	9.540	Up-regulation
Atypical_PIKK_ATM_ATM_ST	Q9Y2K7	KDM2A	Q13315	ATM	S394	S390F	390	Missense	distal	-4	no	10.277	8.878	EPSD	TCGA;ICGC;COSMIC	9.540	Loss
Atypical_PIKK_ATM_ATM_ST	Q9Y2K7	KDM2A	Q13315	ATM	T632	Q628E	628	Missense	distal	-4	no	14.847	15.570	PhosphoSitePlus	TCGA;ICGC;COSMIC	9.540	Up-regulation
Atypical_PIKK_ATM_ATM_ST	Q9Y2K7	KDM2A	Q13315	ATM	S718	T713M	713	Missense	distal	-5	no	9.564	9.737	EPSD	TCGA;ICGC;COSMIC;GDSC	9.540	Up-regulation
Atypical_PIKK_ATM_ATM_ST	Q9Y2K7	KDM2A	Q13315	ATM	T737	R738Q	738	Missense	proximal	1	no	5.951	12.603	EPSD	TCGA;ICGC	9.540	Gain
Atypical_PIKK_ATM_ATM_ST	Q9Y2K7	KDM2A	Q13315	ATM	S797	T802M	802	Missense	distal	5	no	9.600	9.801	EPSD	TCGA;COSMIC	9.540	Up-regulation
Atypical_PIKK_ATM_ATM_ST	Q9Y2K7	KDM2A	Q13315	ATM	S797	S797L	797	Missense	central	0	yes	9.600	0.000	EPSD	TCGA;COSMIC;CCLE	9.540	Loss
Atypical_PIKK_ATM_ATM_ST	Q9Y2K7	KDM2A	Q13315	ATM	S797	R795W	795	Missense	proximal	-2	no	9.600	9.549	EPSD	TCGA;ICGC;COSMIC	9.540	Down-regulation
Atypical_PIKK_ATM_ATM_ST	Q02535	ID3	Q13315	ATM	S65	I69T	69	Missense	distal	4	no	14.211	13.636	PhosphoSitePlus	TCGA;ICGC;COSMIC	9.540	Down-regulation
Atypical_PIKK_ATM_ATM_ST	Q02535	ID3	Q13315	ATM	S65	E68K	68	Missense	distal	3	no	14.211	14.500	PhosphoSitePlus	TCGA;ICGC;COSMIC	9.540	Up-regulation
Atypical_PIKK_ATM_ATM_ST	Q02535	ID3	Q13315	ATM	S65	Q71K	71	Missense	distal	6	no	14.211	14.213	PhosphoSitePlus	TCGA;ICGC;COSMIC	9.540	Up-regulation
Atypical_PIKK_ATM_ATM_ST	P46379	BAG6	Q13315	ATM	S26	I32S	32	Missense	distal	6	no	15.861	15.901	PhosphoSitePlus;EPSD	TCGA;ICGC	9.540	Up-regulation
Atypical_PIKK_ATM_ATM_ST	P46379	BAG6	Q13315	ATM	S104	S99Y	99	Missense	distal	-5	no	10.760	10.784	EPSD	TCGA;ICGC;COSMIC	9.540	Up-regulation
Atypical_PIKK_ATM_ATM_ST	P46379	BAG6	Q13315	ATM	S113	P115S	115	Missense	proximal	2	no	9.273	9.728	EPSD	TCGA;ICGC;COSMIC	9.540	Gain
Atypical_PIKK_ATM_ATM_ST	P46379	BAG6	Q13315	ATM	S200	P204L	204	Missense	distal	4	no	15.092	15.311	EPSD	TCGA;COSMIC	9.540	Up-regulation
Atypical_PIKK_ATM_ATM_ST	P46379	BAG6	Q13315	ATM	S218	P211L	211	Missense	distal	-7	no	14.170	13.819	EPSD;PhosphoSitePlus	TCGA;COSMIC;GDSC;CCLE	9.540	Down-regulation
Atypical_PIKK_ATM_ATM_ST	P46379	BAG6	Q13315	ATM	S964	R969W	969	Missense	distal	5	no	10.101	10.125	EPSD	TCGA;COSMIC;GDSC	9.540	Up-regulation
Atypical_PIKK_ATM_ATM_ST	P46379	BAG6	Q13315	ATM	S1064	E1065Q	1065	Missense	proximal	1	no	7.023	12.919	EPSD	TCGA;COSMIC;GDSC;CCLE	9.540	Gain
Atypical_PIKK_ATM_ATM_ST	P46379	BAG6	Q13315	ATM	S1081	E1083K	1083	Missense	proximal	2	no	9.713	8.382	EPSD	TCGA;COSMIC	9.540	Loss
Atypical_PIKK_ATM_ATM_ST	P46379	BAG6	Q13315	ATM	S1081	R1087W	1087	Missense	distal	6	no	9.713	9.682	EPSD	TCGA;COSMIC	9.540	Down-regulation
Atypical_PIKK_ATM_ATM_ST	P46379	BAG6	Q13315	ATM	S1081	R1087Q	1087	Missense	distal	6	no	9.713	9.709	EPSD	TCGA;COSMIC	9.540	Down-regulation
Atypical_PIKK_ATM_ATM_ST	P46379	BAG6	Q13315	ATM	S1086	R1087Q	1087	Missense	proximal	1	no	6.787	13.439	EPSD	TCGA;COSMIC	9.540	Gain
Atypical_PIKK_ATM_ATM_ST	P46379	BAG6	Q13315	ATM	S1117	E1112K	1112	Missense	distal	-5	no	11.984	12.066	EPSD	TCGA;COSMIC	9.540	Up-regulation
Atypical_PIKK_ATM_ATM_ST	P46379	BAG6	Q13315	ATM	S1117	S1117I	1117	Missense	central	0	yes	11.984	0.000	EPSD	TCGA	9.540	Loss
Atypical_PIKK_ATM_ATM_ST	Q9NUW8	TDP1	Q13315	ATM	S2	D6N	6	Missense	distal	4	no	11.635	11.554	EPSD	TCGA;ICGC;COSMIC	9.540	Down-regulation
Atypical_PIKK_ATM_ATM_ST	Q9NUW8	TDP1	Q13315	ATM	S18	E21Q	21	Missense	distal	3	no	9.644	9.903	EPSD	TCGA;ICGC;COSMIC	9.540	Up-regulation
Atypical_PIKK_ATM_ATM_ST	Q9NUW8	TDP1	Q13315	ATM	S18	E20G	20	Missense	proximal	2	no	9.644	8.275	EPSD	TCGA;ICGC;COSMIC	9.540	Loss
Atypical_PIKK_ATM_ATM_ST	Q9NUW8	TDP1	Q13315	ATM	S61	S61L	61	Missense	central	0	yes	9.920	0.000	EPSD	TCGA;ICGC;COSMIC	9.540	Loss
Atypical_PIKK_ATM_ATM_ST	Q9NUW8	TDP1	Q13315	ATM	S61	R58G	58	Missense	distal	-3	no	9.920	9.458	EPSD	TCGA;ICGC;COSMIC	9.540	Loss
Atypical_PIKK_ATM_ATM_ST	Q9NUW8	TDP1	Q13315	ATM	S81	G80C	80	Missense	proximal	-1	no	15.092	15.084	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	9.540	Down-regulation
Atypical_PIKK_ATM_ATM_ST	Q9NUW8	TDP1	Q13315	ATM	S81	G80V	80	Missense	proximal	-1	no	15.092	14.860	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	9.540	Down-regulation
Atypical_PIKK_ATM_ATM_ST	Q9NUW8	TDP1	Q13315	ATM	S81	S81F	81	Missense	central	0	yes	15.092	0.000	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	9.540	Loss
Atypical_PIKK_ATM_ATM_ST	Q9NUW8	TDP1	Q13315	ATM	S148	G149W	149	Missense	proximal	1	no	11.780	5.649	EPSD	TCGA;ICGC;COSMIC	9.540	Loss
Atypical_PIKK_ATM_ATM_ST	Q9NUW8	TDP1	Q13315	ATM	S148	E146K	146	Missense	proximal	-2	no	11.780	11.205	EPSD	TCGA;ICGC;COSMIC	9.540	Down-regulation
Atypical_PIKK_ATM_ATM_ST	Q9NUW8	TDP1	Q13315	ATM	S148	I154M	154	Missense	distal	6	no	11.780	11.792	EPSD	TCGA	9.540	Up-regulation
Atypical_PIKK_ATM_ATM_ST	Q9NUW8	TDP1	Q13315	ATM	S563	A568G	568	Missense	distal	5	no	17.540	17.670	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	9.540	Up-regulation
Atypical_PIKK_ATM_ATM_ST	Q9NUW8	TDP1	Q13315	ATM	S563	K558T	558	Missense	distal	-5	no	17.540	17.534	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	9.540	Down-regulation
Atypical_PIKK_ATM_ATM_ST	Q14683	SMC1A	Q13315	ATM	S85	E90K	90	Missense	distal	5	no	10.883	11.058	EPSD	TCGA;ICGC;COSMIC	9.540	Up-regulation
Atypical_PIKK_ATM_ATM_ST	Q14683	SMC1A	Q13315	ATM	S103	R96H	96	Missense	distal	-7	no	9.499	9.585	EPSD	TCGA;ICGC;COSMIC	9.540	Gain
Atypical_PIKK_ATM_ATM_ST	Q14683	SMC1A	Q13315	ATM	T182	R188C	188	Missense	distal	6	no	12.377	12.323	EPSD	TCGA;ICGC;COSMIC	9.540	Down-regulation
Atypical_PIKK_ATM_ATM_ST	Q14683	SMC1A	Q13315	ATM	T182	R188H	188	Missense	distal	6	no	12.377	12.362	EPSD	TCGA;ICGC;COSMIC	9.540	Down-regulation
Atypical_PIKK_ATM_ATM_ST	Q14683	SMC1A	Q13315	ATM	T182	D181N	181	Missense	proximal	-1	no	12.377	12.376	EPSD	TCGA;ICGC	9.540	Down-regulation
Atypical_PIKK_ATM_ATM_ST	Q14683	SMC1A	Q13315	ATM	T182	F184L	184	Missense	proximal	2	no	12.377	12.612	EPSD	TCGA;ICGC;COSMIC	9.540	Up-regulation
Atypical_PIKK_ATM_ATM_ST	Q14683	SMC1A	Q13315	ATM	T182	K189N	189	Missense	distal	7	no	12.377	12.369	EPSD	TCGA;ICGC;COSMIC	9.540	Down-regulation
Atypical_PIKK_ATM_ATM_ST	Q14683	SMC1A	Q13315	ATM	S358	E357D	357	Missense	proximal	-1	no	15.601	15.336	EPSD	TCGA;ICGC;COSMIC	9.540	Down-regulation
Atypical_PIKK_ATM_ATM_ST	Q14683	SMC1A	Q13315	ATM	S358	E357K	357	Missense	proximal	-1	no	15.601	15.198	EPSD	TCGA;ICGC;COSMIC	9.540	Down-regulation
Atypical_PIKK_ATM_ATM_ST	Q14683	SMC1A	Q13315	ATM	S358	R353W	353	Missense	distal	-5	no	15.601	15.767	EPSD	TCGA;ICGC;COSMIC	9.540	Up-regulation
Atypical_PIKK_ATM_ATM_ST	Q14683	SMC1A	Q13315	ATM	S360	E357D	357	Missense	distal	-3	no	15.422	15.827	EPSD	TCGA;ICGC;COSMIC	9.540	Up-regulation
Atypical_PIKK_ATM_ATM_ST	Q14683	SMC1A	Q13315	ATM	S360	E357K	357	Missense	distal	-3	no	15.422	15.489	EPSD	TCGA;ICGC;COSMIC	9.540	Up-regulation
Atypical_PIKK_ATM_ATM_ST	Q14683	SMC1A	Q13315	ATM	S360	R353W	353	Missense	distal	-7	no	15.422	15.232	EPSD	TCGA;ICGC;COSMIC	9.540	Down-regulation
Atypical_PIKK_ATM_ATM_ST	Q14683	SMC1A	Q13315	ATM	S703	R699C	699	Missense	distal	-4	no	15.804	15.042	EPSD	TCGA;ICGC;COSMIC	9.540	Down-regulation
Atypical_PIKK_ATM_ATM_ST	Q14683	SMC1A	Q13315	ATM	S703	S703P	703	Missense	central	0	yes	15.804	0.000	EPSD	TCGA;ICGC	9.540	Loss
Atypical_PIKK_ATM_ATM_ST	Q14683	SMC1A	Q13315	ATM	S715	D718E	718	Missense	distal	3	no	13.230	12.871	EPSD	TCGA;ICGC;COSMIC	9.540	Down-regulation
Atypical_PIKK_ATM_ATM_ST	Q14683	SMC1A	Q13315	ATM	S715	R711W	711	Missense	distal	-4	no	13.230	12.754	EPSD	TCGA;ICGC;COSMIC;GDSC;CCLE	9.540	Down-regulation
Atypical_PIKK_ATM_ATM_ST	Q14683	SMC1A	Q13315	ATM	S715	R711Q	711	Missense	distal	-4	no	13.230	13.595	EPSD	TCGA;ICGC;COSMIC;GDSC;CCLE	9.540	Up-regulation
Atypical_PIKK_ATM_ATM_ST	Q14683	SMC1A	Q13315	ATM	S957	E960G	960	Missense	distal	3	no	14.210	14.517	PhosphoSitePlus;EPSD	TCGA;ICGC;COSMIC	9.540	Up-regulation
Atypical_PIKK_ATM_ATM_ST	Q14683	SMC1A	Q13315	ATM	S964	S966T	966	Missense	proximal	2	no	10.957	10.695	EPSD	TCGA;ICGC;COSMIC	9.540	Down-regulation
Atypical_PIKK_ATM_ATM_ST	Q14683	SMC1A	Q13315	ATM	S964	E960G	960	Missense	distal	-4	no	10.957	9.890	EPSD	TCGA;ICGC;COSMIC	9.540	Down-regulation
Atypical_PIKK_ATM_ATM_ST	Q14683	SMC1A	Q13315	ATM	S966	Y973C	973	Missense	distal	7	no	14.373	14.391	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	9.540	Up-regulation
Atypical_PIKK_ATM_ATM_ST	Q14683	SMC1A	Q13315	ATM	S966	E960G	960	Missense	distal	-6	no	14.373	13.984	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	9.540	Down-regulation
Atypical_PIKK_ATM_ATM_ST	P54132	BLM	Q13315	ATM	S74	E75K	75	Missense	proximal	1	no	13.187	12.236	EPSD	TCGA;ICGC;COSMIC	9.540	Down-regulation
Atypical_PIKK_ATM_ATM_ST	P54132	BLM	Q13315	ATM	T99	Q100H	100	Missense	proximal	1	no	13.631	-1.278	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	9.540	Loss
Atypical_PIKK_ATM_ATM_ST	P54132	BLM	Q13315	ATM	T99	A93D	93	Missense	distal	-6	no	13.631	13.624	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	9.540	Down-regulation
Atypical_PIKK_ATM_ATM_ST	P54132	BLM	Q13315	ATM	T99	Q97H	97	Missense	proximal	-2	no	13.631	13.327	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	9.540	Down-regulation
Atypical_PIKK_ATM_ATM_ST	P54132	BLM	Q13315	ATM	T122	T125P	125	Missense	distal	3	no	13.098	13.170	PhosphoSitePlus;EPSD	TCGA;ICGC;COSMIC	9.540	Up-regulation
Atypical_PIKK_ATM_ATM_ST	P54132	BLM	Q13315	ATM	S166	D159E	159	Missense	distal	-7	no	9.902	10.480	EPSD	TCGA;ICGC;COSMIC	9.540	Up-regulation
Atypical_PIKK_ATM_ATM_ST	P54132	BLM	Q13315	ATM	S419	D420G	420	Missense	proximal	1	no	11.145	10.702	EPSD	TCGA;ICGC	9.540	Down-regulation
Atypical_PIKK_ATM_ATM_ST	P54132	BLM	Q13315	ATM	S426	D433H	433	Missense	distal	7	no	11.389	11.410	EPSD	TCGA;ICGC;COSMIC	9.540	Up-regulation
Atypical_PIKK_ATM_ATM_ST	P54132	BLM	Q13315	ATM	S426	R431K	431	Missense	distal	5	no	11.389	11.228	EPSD	TCGA;ICGC;COSMIC	9.540	Down-regulation
Atypical_PIKK_ATM_ATM_ST	P54132	BLM	Q13315	ATM	S426	R429K	429	Missense	distal	3	no	11.389	11.317	EPSD	TCGA;ICGC;COSMIC	9.540	Down-regulation
Atypical_PIKK_ATM_ATM_ST	P54132	BLM	Q13315	ATM	S426	D420G	420	Missense	distal	-6	no	11.389	11.215	EPSD	TCGA;ICGC	9.540	Down-regulation
Atypical_PIKK_ATM_ATM_ST	P54132	BLM	Q13315	ATM	S464	S462Y	462	Missense	proximal	-2	no	11.465	11.295	EPSD	TCGA;ICGC;COSMIC	9.540	Down-regulation
Atypical_PIKK_ATM_ATM_ST	P54132	BLM	Q13315	ATM	S550	E546Q	546	Missense	distal	-4	no	12.539	11.815	EPSD	TCGA;ICGC;COSMIC	9.540	Down-regulation
Atypical_PIKK_ATM_ATM_ST	P54132	BLM	Q13315	ATM	S646	K653M	653	Missense	distal	7	no	10.302	10.313	EPSD	TCGA;ICGC;COSMIC	9.540	Up-regulation
Atypical_PIKK_ATM_ATM_ST	P54132	BLM	Q13315	ATM	S646	L647I	647	Missense	proximal	1	no	10.302	-0.067	EPSD	TCGA;COSMIC	9.540	Loss
Atypical_PIKK_ATM_ATM_ST	P54132	BLM	Q13315	ATM	S646	R643C	643	Missense	distal	-3	no	10.302	9.730	EPSD	TCGA;ICGC;COSMIC	9.540	Down-regulation
Atypical_PIKK_ATM_ATM_ST	P54132	BLM	Q13315	ATM	S646	K653N	653	Missense	distal	7	no	10.302	10.294	EPSD	TCGA;ICGC;COSMIC	9.540	Down-regulation
Atypical_PIKK_ATM_ATM_ST	P54132	BLM	Q13315	ATM	T830	S823C	823	Missense	distal	-7	no	9.736	9.062	EPSD	TCGA;ICGC;COSMIC	9.540	Loss
Atypical_PIKK_ATM_ATM_ST	P54132	BLM	Q13315	ATM	T830	N834Y	834	Missense	distal	4	no	9.736	9.912	EPSD	TCGA;ICGC;COSMIC	9.540	Up-regulation
Atypical_PIKK_ATM_ATM_ST	P54132	BLM	Q13315	ATM	T830	M827I	827	Missense	distal	-3	no	9.736	10.050	EPSD	TCGA;ICGC;COSMIC	9.540	Up-regulation
Atypical_PIKK_ATM_ATM_ST	P54132	BLM	Q13315	ATM	T830	S823F	823	Missense	distal	-7	no	9.736	8.906	EPSD	TCGA;ICGC;COSMIC	9.540	Loss
Atypical_PIKK_ATM_ATM_ST	P54132	BLM	Q13315	ATM	T830	P825Q	825	Missense	distal	-5	no	9.736	9.599	EPSD	TCGA;ICGC;COSMIC	9.540	Down-regulation
Atypical_PIKK_ATM_ATM_ST	P54132	BLM	Q13315	ATM	S1394	Q1387E	1387	Missense	distal	-7	no	9.207	9.762	EPSD	TCGA;ICGC;COSMIC	9.540	Gain
Atypical_PIKK_ATM_ATM_ST	Q14190	SIM2	Q13315	ATM	S35	A40V	40	Missense	distal	5	no	14.063	14.227	EPSD	TCGA;ICGC;COSMIC	9.540	Up-regulation
Atypical_PIKK_ATM_ATM_ST	Q14190	SIM2	Q13315	ATM	S115	S109F	109	Missense	distal	-6	no	11.783	11.252	PhosphoSitePlus	TCGA;ICGC;COSMIC	9.540	Down-regulation
Atypical_PIKK_ATM_ATM_ST	Q14190	SIM2	Q13315	ATM	S115	G121S	121	Missense	distal	6	no	11.783	11.802	PhosphoSitePlus	TCGA;ICGC	9.540	Up-regulation
Atypical_PIKK_ATM_ATM_ST	Q14190	SIM2	Q13315	ATM	S115	N122S	122	Missense	distal	7	no	11.783	11.768	PhosphoSitePlus	TCGA;ICGC	9.540	Down-regulation
Atypical_PIKK_ATM_ATM_ST	Q14190	SIM2	Q13315	ATM	S115	T120M	120	Missense	distal	5	no	11.783	11.985	PhosphoSitePlus	TCGA;ICGC;COSMIC	9.540	Up-regulation
Atypical_PIKK_ATM_ATM_ST	Q14190	SIM2	Q13315	ATM	S115	G113C	113	Missense	proximal	-2	no	11.783	11.764	PhosphoSitePlus	TCGA;ICGC;COSMIC	9.540	Down-regulation
Atypical_PIKK_ATM_ATM_ST	Q14190	SIM2	Q13315	ATM	S186	K190N	190	Missense	distal	4	no	10.241	10.289	EPSD	TCGA;ICGC;COSMIC	9.540	Up-regulation
Atypical_PIKK_ATM_ATM_ST	Q14190	SIM2	Q13315	ATM	S237	F234L	234	Missense	distal	-3	no	11.214	10.352	EPSD	TCGA;ICGC;COSMIC	9.540	Down-regulation
Atypical_PIKK_ATM_ATM_ST	Q14190	SIM2	Q13315	ATM	S237	F232L	232	Missense	distal	-5	no	11.214	10.914	EPSD	TCGA;ICGC;COSMIC	9.540	Down-regulation
Atypical_PIKK_ATM_ATM_ST	Q14190	SIM2	Q13315	ATM	S237	L240P	240	Missense	distal	3	no	11.214	11.084	EPSD	TCGA;ICGC;COSMIC	9.540	Down-regulation
Atypical_PIKK_ATM_ATM_ST	Q14190	SIM2	Q13315	ATM	S237	S237G	237	Missense	central	0	yes	11.214	0.000	EPSD	TCGA;ICGC;COSMIC	9.540	Loss
Atypical_PIKK_ATM_ATM_ST	Q14190	SIM2	Q13315	ATM	S343	L340F	340	Missense	distal	-3	no	9.160	10.023	EPSD	TCGA	9.540	Gain
Atypical_PIKK_ATM_ATM_ST	Q14190	SIM2	Q13315	ATM	S502	S503Y	503	Missense	proximal	1	no	4.777	10.838	EPSD	TCGA;ICGC;COSMIC	9.540	Gain
Atypical_PIKK_ATM_ATM_ST	Q14190	SIM2	Q13315	ATM	S523	S519R	519	Missense	distal	-4	no	10.969	10.158	EPSD	TCGA;ICGC;COSMIC	9.540	Down-regulation
Atypical_PIKK_ATM_ATM_ST	P54274	TERF1	Q13315	ATM	T24	Q27H	27	Missense	distal	3	no	9.596	9.737	EPSD	TCGA;ICGC;COSMIC	9.540	Up-regulation
Atypical_PIKK_ATM_ATM_ST	P54274	TERF1	Q13315	ATM	T24	A21V	21	Missense	distal	-3	no	9.596	10.460	EPSD	TCGA;ICGC;COSMIC	9.540	Up-regulation
Atypical_PIKK_ATM_ATM_ST	P54274	TERF1	Q13315	ATM	T24	T31R	31	Missense	distal	7	no	9.596	9.615	EPSD	TCGA;ICGC;COSMIC	9.540	Up-regulation
Atypical_PIKK_ATM_ATM_ST	P54274	TERF1	Q13315	ATM	T24	R19G	19	Missense	distal	-5	no	9.596	9.575	EPSD	TCGA;ICGC;COSMIC	9.540	Down-regulation
Atypical_PIKK_ATM_ATM_ST	P54274	TERF1	Q13315	ATM	T24	A29V	29	Missense	distal	5	no	9.596	9.761	EPSD	TCGA;ICGC;COSMIC	9.540	Up-regulation
Atypical_PIKK_ATM_ATM_ST	P54274	TERF1	Q13315	ATM	S114	I108S	108	Missense	distal	-6	no	9.744	10.145	EPSD	TCGA;ICGC;COSMIC	9.540	Up-regulation
Atypical_PIKK_ATM_ATM_ST	P54274	TERF1	Q13315	ATM	S114	I109S	109	Missense	distal	-5	no	9.744	9.630	EPSD	TCGA;ICGC;COSMIC	9.540	Down-regulation
Atypical_PIKK_ATM_ATM_ST	P54274	TERF1	Q13315	ATM	S219	F224C	224	Missense	distal	5	no	14.562	14.482	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	9.540	Down-regulation
Atypical_PIKK_ATM_ATM_ST	P54274	TERF1	Q13315	ATM	T330	D334N	334	Missense	distal	4	no	11.179	11.098	EPSD	TCGA	9.540	Down-regulation
Atypical_PIKK_ATM_ATM_ST	P54274	TERF1	Q13315	ATM	S367	I362M	362	Missense	distal	-5	no	16.705	16.675	PhosphoSitePlus;EPSD	TCGA;COSMIC	9.540	Down-regulation
Atypical_PIKK_ATM_ATM_ST	P54274	TERF1	Q13315	ATM	S367	P369S	369	Missense	proximal	2	no	16.705	17.160	PhosphoSitePlus;EPSD	TCGA;COSMIC	9.540	Up-regulation
Atypical_PIKK_ATM_ATM_ST	P54274	TERF1	Q13315	ATM	S404	G399V	399	Missense	distal	-5	no	10.048	10.107	EPSD	TCGA;COSMIC	9.540	Up-regulation
Atypical_PIKK_ATM_ATM_ST	P54274	TERF1	Q13315	ATM	S435	S434F	434	Missense	proximal	-1	no	9.678	9.251	EPSD	TCGA;COSMIC	9.540	Loss
Atypical_PIKK_ATM_ATM_ST	P54274	TERF1	Q13315	ATM	S437	S434F	434	Missense	distal	-3	no	12.023	13.095	EPSD	TCGA;COSMIC	9.540	Up-regulation
Atypical_PIKK_ATM_ATM_ST	Q14161	GIT2	Q13315	ATM	S46	S40N	40	Missense	distal	-6	no	12.860	12.744	EPSD	TCGA;ICGC;COSMIC	9.540	Down-regulation
Atypical_PIKK_ATM_ATM_ST	Q14161	GIT2	Q13315	ATM	S46	H44Q	44	Missense	proximal	-2	no	12.860	13.163	EPSD	TCGA;ICGC;COSMIC	9.540	Up-regulation
Atypical_PIKK_ATM_ATM_ST	Q14161	GIT2	Q13315	ATM	S46	R43H	43	Missense	distal	-3	no	12.860	12.215	EPSD	TCGA;ICGC	9.540	Down-regulation
Atypical_PIKK_ATM_ATM_ST	Q14161	GIT2	Q13315	ATM	S415	S421L	421	Missense	distal	6	no	12.027	11.971	EPSD	TCGA;ICGC;COSMIC	9.540	Down-regulation
Atypical_PIKK_ATM_ATM_ST	Q14161	GIT2	Q13315	ATM	S415	N411T	411	Missense	distal	-4	no	12.027	12.572	EPSD	TCGA;COSMIC	9.540	Up-regulation
Atypical_PIKK_ATM_ATM_ST	Q14161	GIT2	Q13315	ATM	S590	E589D	589	Missense	proximal	-1	no	10.566	10.301	EPSD	TCGA;COSMIC	9.540	Down-regulation
Atypical_PIKK_ATM_ATM_ST	Q14161	GIT2	Q13315	ATM	S634	A627V	627	Missense	distal	-7	no	10.775	10.392	EPSD	TCGA;ICGC;COSMIC	9.540	Down-regulation
Atypical_PIKK_ATM_ATM_ST	Q14161	GIT2	Q13315	ATM	S634	P635T	635	Missense	proximal	1	no	10.775	5.768	EPSD	TCGA;ICGC;COSMIC	9.540	Loss
Atypical_PIKK_ATM_ATM_ST	Q14161	GIT2	Q13315	ATM	S724	T717I	717	Missense	distal	-7	no	10.205	9.621	EPSD	TCGA;ICGC;COSMIC;GDSC;CCLE	9.540	Down-regulation
Atypical_PIKK_ATM_ATM_ST	Q14161	GIT2	Q13315	ATM	S724	S724L	724	Missense	central	0	yes	10.205	0.000	EPSD	TCGA;ICGC;COSMIC	9.540	Loss
Atypical_PIKK_ATM_ATM_ST	Q14161	GIT2	Q13315	ATM	S724	P719S	719	Missense	distal	-5	no	10.205	10.201	EPSD	TCGA;ICGC;COSMIC	9.540	Down-regulation
Atypical_PIKK_ATM_ATM_ST	Q14161	GIT2	Q13315	ATM	T732	Q734E	734	Missense	proximal	2	no	11.112	11.925	EPSD	TCGA;ICGC;COSMIC	9.540	Up-regulation
Atypical_PIKK_ATM_ATM_ST	Q14161	GIT2	Q13315	ATM	T732	Q737R	737	Missense	distal	5	no	11.112	11.224	EPSD	TCGA;COSMIC	9.540	Up-regulation
Atypical_PIKK_ATM_ATM_ST	Q14161	GIT2	Q13315	ATM	T732	A739V	739	Missense	distal	7	no	11.112	11.130	EPSD	TCGA;COSMIC	9.540	Up-regulation
Atypical_PIKK_ATM_ATM_ST	Q5XUX0	FBXO31	Q13315	ATM	S278	I275M	275	Missense	distal	-3	no	13.114	12.799	PhosphoSitePlus	TCGA;ICGC;COSMIC	9.540	Down-regulation
Atypical_PIKK_ATM_ATM_ST	Q5XUX0	FBXO31	Q13315	ATM	S278	Y276N	276	Missense	proximal	-2	no	13.114	13.104	PhosphoSitePlus	TCGA;ICGC;COSMIC	9.540	Down-regulation
Atypical_PIKK_ATM_ATM_ST	Q5XUX0	FBXO31	Q13315	ATM	S278	F274Y	274	Missense	distal	-4	no	13.114	13.412	PhosphoSitePlus	TCGA;ICGC	9.540	Up-regulation
Atypical_PIKK_ATM_ATM_ST	Q5XUX0	FBXO31	Q13315	ATM	S400	P397S	397	Missense	distal	-3	no	14.920	14.724	EPSD	TCGA;ICGC;COSMIC	9.540	Down-regulation
Atypical_PIKK_ATM_ATM_ST	Q5XUX0	FBXO31	Q13315	ATM	S400	R398W	398	Missense	proximal	-2	no	14.920	14.869	EPSD	TCGA;ICGC;COSMIC	9.540	Down-regulation
Atypical_PIKK_ATM_ATM_ST	Q5XUX0	FBXO31	Q13315	ATM	S400	R398Q	398	Missense	proximal	-2	no	14.920	15.239	EPSD	TCGA;ICGC;COSMIC	9.540	Up-regulation
Atypical_PIKK_ATM_ATM_ST	Q5XUX0	FBXO31	Q13315	ATM	S403	P397S	397	Missense	distal	-6	no	11.239	11.298	EPSD	TCGA;ICGC;COSMIC	9.540	Up-regulation
Atypical_PIKK_ATM_ATM_ST	Q5XUX0	FBXO31	Q13315	ATM	S403	R398W	398	Missense	distal	-5	no	11.239	11.404	EPSD	TCGA;ICGC;COSMIC	9.540	Up-regulation
Atypical_PIKK_ATM_ATM_ST	Q5XUX0	FBXO31	Q13315	ATM	S403	E410D	410	Missense	distal	7	no	11.239	11.251	EPSD	TCGA;ICGC;COSMIC	9.540	Up-regulation
Atypical_PIKK_ATM_ATM_ST	Q5XUX0	FBXO31	Q13315	ATM	S403	R398Q	398	Missense	distal	-5	no	11.239	11.029	EPSD	TCGA;ICGC;COSMIC	9.540	Down-regulation
Atypical_PIKK_ATM_ATM_ST	Q92905	COPS5	Q13315	ATM	S270	E274Q	274	Missense	distal	4	no	9.440	9.772	EPSD	TCGA;ICGC;COSMIC	9.540	Gain
Atypical_PIKK_ATM_ATM_ST	Q92905	COPS5	Q13315	ATM	S270	K272N	272	Missense	proximal	2	no	9.440	9.619	EPSD	TCGA;ICGC;COSMIC	9.540	Gain
Atypical_PIKK_ATM_ATM_ST	Q92905	COPS5	Q13315	ATM	S276	E274Q	274	Missense	proximal	-2	no	10.226	9.921	EPSD	TCGA;ICGC;COSMIC	9.540	Down-regulation
Atypical_PIKK_ATM_ATM_ST	Q92905	COPS5	Q13315	ATM	S276	K272N	272	Missense	distal	-4	no	10.226	9.991	EPSD	TCGA;ICGC;COSMIC	9.540	Down-regulation
Atypical_PIKK_ATM_ATM_ST	Q92905	COPS5	Q13315	ATM	S320	A314D	314	Missense	distal	-6	no	15.790	15.783	PhosphoSitePlus	TCGA;ICGC;COSMIC	9.540	Down-regulation
Atypical_PIKK_ATM_ATM_ST	Q8WVD3	RNF138	Q13315	ATM	S124	N130S	130	Missense	distal	6	no	14.483	14.493	PhosphoSitePlus	TCGA;ICGC;COSMIC	9.540	Up-regulation
Atypical_PIKK_ATM_ATM_ST	P15336	ATF2	Q13315	ATM	S112	T116A	116	Missense	distal	4	no	10.016	9.581	EPSD	TCGA;COSMIC	9.540	Down-regulation
Atypical_PIKK_ATM_ATM_ST	P15336	ATF2	Q13315	ATM	S112	S112P	112	Missense	central	0	yes	10.016	0.000	EPSD	TCGA;COSMIC	9.540	Loss
Atypical_PIKK_ATM_ATM_ST	P15336	ATF2	Q13315	ATM	T283	P288S	288	Missense	distal	5	no	11.837	11.655	EPSD	TCGA;COSMIC	9.540	Down-regulation
Atypical_PIKK_ATM_ATM_ST	P15336	ATF2	Q13315	ATM	T305	P312L	312	Missense	distal	7	no	9.756	9.757	EPSD	TCGA;COSMIC	9.540	Up-regulation
Atypical_PIKK_ATM_ATM_ST	P15336	ATF2	Q13315	ATM	T305	E308Q	308	Missense	distal	3	no	9.756	10.015	EPSD	TCGA;COSMIC	9.540	Up-regulation
Atypical_PIKK_ATM_ATM_ST	P15336	ATF2	Q13315	ATM	T305	R304S	304	Missense	proximal	-1	no	9.756	10.131	EPSD	TCGA;COSMIC	9.540	Up-regulation
Atypical_PIKK_ATM_ATM_ST	P15336	ATF2	Q13315	ATM	T305	S310F	310	Missense	distal	5	no	9.756	10.062	EPSD	TCGA;COSMIC	9.540	Up-regulation
Atypical_PIKK_ATM_ATM_ST	P15336	ATF2	Q13315	ATM	S307	P312L	312	Missense	distal	5	no	10.402	10.385	EPSD	TCGA;COSMIC	9.540	Down-regulation
Atypical_PIKK_ATM_ATM_ST	P15336	ATF2	Q13315	ATM	S307	E308Q	308	Missense	proximal	1	no	10.402	16.299	EPSD	TCGA;COSMIC	9.540	Up-regulation
Atypical_PIKK_ATM_ATM_ST	P15336	ATF2	Q13315	ATM	S307	R304S	304	Missense	distal	-3	no	10.402	9.662	EPSD	TCGA;COSMIC	9.540	Down-regulation
Atypical_PIKK_ATM_ATM_ST	P15336	ATF2	Q13315	ATM	S307	S310F	310	Missense	distal	3	no	10.402	10.984	EPSD	TCGA;COSMIC	9.540	Up-regulation
Atypical_PIKK_ATM_ATM_ST	P15336	ATF2	Q13315	ATM	S328	P326S	326	Missense	proximal	-2	no	10.429	10.666	EPSD	TCGA;COSMIC	9.540	Up-regulation
Atypical_PIKK_ATM_ATM_ST	P15336	ATF2	Q13315	ATM	S328	P334A	334	Missense	distal	6	no	10.429	10.447	EPSD	TCGA;COSMIC	9.540	Up-regulation
Atypical_PIKK_ATM_ATM_ST	P15336	ATF2	Q13315	ATM	S328	S321F	321	Missense	distal	-7	no	10.429	9.600	EPSD	TCGA;COSMIC	9.540	Down-regulation
Atypical_PIKK_ATM_ATM_ST	P15336	ATF2	Q13315	ATM	T336	P334A	334	Missense	proximal	-2	no	12.972	13.021	EPSD	TCGA;COSMIC	9.540	Up-regulation
Atypical_PIKK_ATM_ATM_ST	P15336	ATF2	Q13315	ATM	T336	T339A	339	Missense	distal	3	no	12.972	12.947	EPSD	TCGA;COSMIC	9.540	Down-regulation
Atypical_PIKK_ATM_ATM_ST	P15336	ATF2	Q13315	ATM	S438	D436N	436	Missense	proximal	-2	no	10.118	10.237	EPSD	TCGA;COSMIC	9.540	Up-regulation
Atypical_PIKK_ATM_ATM_ST	P15336	ATF2	Q13315	ATM	S438	S438L	438	Missense	central	0	yes	10.118	0.000	EPSD	TCGA;COSMIC	9.540	Loss
Atypical_PIKK_ATM_ATM_ST	P15336	ATF2	Q13315	ATM	S446	Q453H	453	Missense	distal	7	no	9.523	9.541	EPSD	TCGA;COSMIC	9.540	Gain
Atypical_PIKK_ATM_ATM_ST	P15336	ATF2	Q13315	ATM	S498	S500L	500	Missense	proximal	2	no	14.814	13.571	EPSD;PhosphoSitePlus	TCGA;COSMIC	9.540	Down-regulation
Atypical_PIKK_ATM_ATM_ST	P15336	ATF2	Q13315	ATM	S498	Q499L	499	Missense	proximal	1	no	14.814	8.458	EPSD;PhosphoSitePlus	TCGA;COSMIC	9.540	Loss
Atypical_PIKK_ATM_ATM_ST	P15336	ATF2	Q13315	ATM	S498	P502L	502	Missense	distal	4	no	14.814	15.034	EPSD;PhosphoSitePlus	TCGA;COSMIC	9.540	Up-regulation
Atypical_PIKK_ATM_ATM_ST	P15336	ATF2	Q13315	ATM	S498	P502T	502	Missense	distal	4	no	14.814	14.780	EPSD;PhosphoSitePlus	TCGA;COSMIC	9.540	Down-regulation
Atypical_PIKK_ATM_ATM_ST	P15336	ATF2	Q13315	ATM	S500	S500L	500	Missense	central	0	yes	14.499	0.000	EPSD	TCGA;COSMIC	9.540	Loss
Atypical_PIKK_ATM_ATM_ST	P15336	ATF2	Q13315	ATM	S500	Q499L	499	Missense	proximal	-1	no	14.499	14.431	EPSD	TCGA;COSMIC	9.540	Down-regulation
Atypical_PIKK_ATM_ATM_ST	P15336	ATF2	Q13315	ATM	S500	P502L	502	Missense	proximal	2	no	14.499	13.710	EPSD	TCGA;COSMIC	9.540	Down-regulation
Atypical_PIKK_ATM_ATM_ST	P15336	ATF2	Q13315	ATM	S500	P502T	502	Missense	proximal	2	no	14.499	14.692	EPSD	TCGA;COSMIC	9.540	Up-regulation
Atypical_PIKK_ATM_ATM_ST	P15336	ATF2	Q13315	ATM	S503	S500L	500	Missense	distal	-3	no	11.977	12.186	EPSD	TCGA;COSMIC	9.540	Up-regulation
Atypical_PIKK_ATM_ATM_ST	P15336	ATF2	Q13315	ATM	S503	Q499L	499	Missense	distal	-4	no	11.977	11.483	EPSD	TCGA;COSMIC	9.540	Down-regulation
Atypical_PIKK_ATM_ATM_ST	P15336	ATF2	Q13315	ATM	S503	P502L	502	Missense	proximal	-1	no	11.977	12.134	EPSD	TCGA;COSMIC	9.540	Up-regulation
Atypical_PIKK_ATM_ATM_ST	P15336	ATF2	Q13315	ATM	S503	P502T	502	Missense	proximal	-1	no	11.977	12.280	EPSD	TCGA;COSMIC	9.540	Up-regulation
Atypical_PIKK_ATM_ATM_ST	Q14676	MDC1	Q13315	ATM	T4	E2K	2	Missense	proximal	-2	no	11.183	10.608	PhosphoSitePlus;EPSD	TCGA;ICGC;COSMIC	9.540	Down-regulation
Atypical_PIKK_ATM_ATM_ST	Q14676	MDC1	Q13315	ATM	S20	S21R	21	Missense	proximal	1	no	7.395	12.521	EPSD	TCGA;ICGC;COSMIC	9.540	Gain
Atypical_PIKK_ATM_ATM_ST	Q14676	MDC1	Q13315	ATM	S21	V28M	28	Missense	distal	7	no	11.922	11.907	EPSD	TCGA;ICGC;COSMIC	9.540	Down-regulation
Atypical_PIKK_ATM_ATM_ST	Q14676	MDC1	Q13315	ATM	S21	S21R	21	Missense	central	0	yes	11.922	0.000	EPSD	TCGA;ICGC;COSMIC	9.540	Loss
Atypical_PIKK_ATM_ATM_ST	Q14676	MDC1	Q13315	ATM	S21	E22K	22	Missense	proximal	1	no	11.922	10.970	EPSD	TCGA;ICGC	9.540	Down-regulation
Atypical_PIKK_ATM_ATM_ST	Q14676	MDC1	Q13315	ATM	S21	E16D	16	Missense	distal	-5	no	11.922	11.876	EPSD	TCGA;ICGC	9.540	Down-regulation
Atypical_PIKK_ATM_ATM_ST	Q14676	MDC1	Q13315	ATM	S23	V28M	28	Missense	distal	5	no	11.007	10.980	EPSD	TCGA;ICGC;COSMIC	9.540	Down-regulation
Atypical_PIKK_ATM_ATM_ST	Q14676	MDC1	Q13315	ATM	S23	S21R	21	Missense	proximal	-2	no	11.007	10.564	EPSD	TCGA;ICGC;COSMIC	9.540	Down-regulation
Atypical_PIKK_ATM_ATM_ST	Q14676	MDC1	Q13315	ATM	S23	E22K	22	Missense	proximal	-1	no	11.007	10.604	EPSD	TCGA;ICGC	9.540	Down-regulation
Atypical_PIKK_ATM_ATM_ST	Q14676	MDC1	Q13315	ATM	S23	E16D	16	Missense	distal	-7	no	11.007	10.429	EPSD	TCGA;ICGC	9.540	Down-regulation
Atypical_PIKK_ATM_ATM_ST	Q14676	MDC1	Q13315	ATM	S292	V287A	287	Missense	distal	-5	no	14.824	14.703	EPSD	TCGA;ICGC;COSMIC	9.540	Down-regulation
Atypical_PIKK_ATM_ATM_ST	Q14676	MDC1	Q13315	ATM	S329	G325D	325	Missense	distal	-4	no	8.974	9.757	EPSD	TCGA;ICGC;COSMIC	9.540	Gain
Atypical_PIKK_ATM_ATM_ST	Q14676	MDC1	Q13315	ATM	T341	P346S	346	Missense	distal	5	no	9.811	9.629	EPSD	TCGA;ICGC;COSMIC	9.540	Down-regulation
Atypical_PIKK_ATM_ATM_ST	Q14676	MDC1	Q13315	ATM	S372	D377H	377	Missense	distal	5	no	13.561	13.615	EPSD	TCGA;ICGC;COSMIC	9.540	Up-regulation
Atypical_PIKK_ATM_ATM_ST	Q14676	MDC1	Q13315	ATM	S372	A374V	374	Missense	proximal	2	no	13.561	13.252	EPSD	TCGA;ICGC	9.540	Down-regulation
Atypical_PIKK_ATM_ATM_ST	Q14676	MDC1	Q13315	ATM	S372	A367V	367	Missense	distal	-5	no	13.561	13.682	EPSD	TCGA;ICGC;COSMIC	9.540	Up-regulation
Atypical_PIKK_ATM_ATM_ST	Q14676	MDC1	Q13315	ATM	S394	K393E	393	Missense	proximal	-1	no	15.205	15.608	EPSD	TCGA	9.540	Up-regulation
Atypical_PIKK_ATM_ATM_ST	Q14676	MDC1	Q13315	ATM	S394	S397F	397	Missense	distal	3	no	15.205	15.787	EPSD	TCGA;ICGC	9.540	Up-regulation
Atypical_PIKK_ATM_ATM_ST	Q14676	MDC1	Q13315	ATM	S422	A417V	417	Missense	distal	-5	no	13.385	13.505	EPSD	TCGA;ICGC;COSMIC	9.540	Up-regulation
Atypical_PIKK_ATM_ATM_ST	Q14676	MDC1	Q13315	ATM	S505	V499M	499	Missense	distal	-6	no	10.156	10.167	EPSD	TCGA;ICGC;COSMIC	9.540	Up-regulation
Atypical_PIKK_ATM_ATM_ST	Q14676	MDC1	Q13315	ATM	S505	H509Y	509	Missense	distal	4	no	10.156	10.341	EPSD	TCGA;ICGC;COSMIC	9.540	Up-regulation
Atypical_PIKK_ATM_ATM_ST	Q14676	MDC1	Q13315	ATM	S513	H509Y	509	Missense	distal	-4	no	14.104	13.683	EPSD	TCGA;ICGC;COSMIC	9.540	Down-regulation
Atypical_PIKK_ATM_ATM_ST	Q14676	MDC1	Q13315	ATM	S598	V591L	591	Missense	distal	-7	no	14.446	14.339	EPSD	TCGA;ICGC	9.540	Down-regulation
Atypical_PIKK_ATM_ATM_ST	Q14676	MDC1	Q13315	ATM	S641	P639L	639	Missense	proximal	-2	no	9.770	9.617	EPSD	TCGA;ICGC;COSMIC	9.540	Down-regulation
Atypical_PIKK_ATM_ATM_ST	Q14676	MDC1	Q13315	ATM	S641	L645I	645	Missense	distal	4	no	9.770	10.091	EPSD	TCGA;ICGC;COSMIC	9.540	Up-regulation
Atypical_PIKK_ATM_ATM_ST	Q14676	MDC1	Q13315	ATM	T659	A666V	666	Missense	distal	7	no	13.856	13.873	EPSD	TCGA;ICGC;COSMIC	9.540	Up-regulation
Atypical_PIKK_ATM_ATM_ST	Q14676	MDC1	Q13315	ATM	T719	A721V	721	Missense	proximal	2	no	13.846	13.537	EPSD	TCGA;ICGC;COSMIC	9.540	Down-regulation
Atypical_PIKK_ATM_ATM_ST	Q14676	MDC1	Q13315	ATM	S760	E761K	761	Missense	proximal	1	no	9.817	8.865	EPSD	TCGA;ICGC;COSMIC	9.540	Loss
Atypical_PIKK_ATM_ATM_ST	Q14676	MDC1	Q13315	ATM	S760	E761D	761	Missense	proximal	1	no	9.817	9.682	EPSD	TCGA;ICGC	9.540	Down-regulation
Atypical_PIKK_ATM_ATM_ST	Q14676	MDC1	Q13315	ATM	T765	T770M	770	Missense	distal	5	no	12.124	12.326	EPSD	TCGA;ICGC;COSMIC	9.540	Up-regulation
Atypical_PIKK_ATM_ATM_ST	Q14676	MDC1	Q13315	ATM	T765	E761K	761	Missense	distal	-4	no	12.124	11.152	EPSD	TCGA;ICGC;COSMIC	9.540	Down-regulation
Atypical_PIKK_ATM_ATM_ST	Q14676	MDC1	Q13315	ATM	T765	E761D	761	Missense	distal	-4	no	12.124	11.841	EPSD	TCGA;ICGC	9.540	Down-regulation
Atypical_PIKK_ATM_ATM_ST	Q14676	MDC1	Q13315	ATM	S780	Y775C	775	Missense	distal	-5	no	9.675	9.744	EPSD	TCGA;ICGC;COSMIC;CCLE	9.540	Up-regulation
Atypical_PIKK_ATM_ATM_ST	Q14676	MDC1	Q13315	ATM	S882	D875H	875	Missense	distal	-7	no	9.638	9.547	EPSD	TCGA;ICGC;COSMIC	9.540	Down-regulation
Atypical_PIKK_ATM_ATM_ST	Q14676	MDC1	Q13315	ATM	S882	E879Q	879	Missense	distal	-3	no	9.638	9.762	EPSD	TCGA;ICGC;COSMIC	9.540	Up-regulation
Atypical_PIKK_ATM_ATM_ST	Q14676	MDC1	Q13315	ATM	T946	E952D	952	Missense	distal	6	no	12.717	12.670	EPSD	TCGA;ICGC	9.540	Down-regulation
Atypical_PIKK_ATM_ATM_ST	Q14676	MDC1	Q13315	ATM	S955	E952D	952	Missense	distal	-3	no	15.531	15.936	EPSD	TCGA;ICGC	9.540	Up-regulation
Atypical_PIKK_ATM_ATM_ST	Q14676	MDC1	Q13315	ATM	S964	S964N	964	Missense	central	0	yes	10.295	0.000	EPSD	TCGA;ICGC	9.540	Loss
Atypical_PIKK_ATM_ATM_ST	Q14676	MDC1	Q13315	ATM	S988	S981L	981	Missense	distal	-7	no	12.287	11.699	EPSD	TCGA;ICGC;COSMIC	9.540	Down-regulation
Atypical_PIKK_ATM_ATM_ST	Q14676	MDC1	Q13315	ATM	S988	G992V	992	Missense	distal	4	no	12.287	12.464	EPSD	TCGA;ICGC;COSMIC	9.540	Up-regulation
Atypical_PIKK_ATM_ATM_ST	Q14676	MDC1	Q13315	ATM	S988	V984I	984	Missense	distal	-4	no	12.287	12.565	EPSD	TCGA;ICGC	9.540	Up-regulation
Atypical_PIKK_ATM_ATM_ST	Q14676	MDC1	Q13315	ATM	S1033	L1038V	1038	Missense	distal	5	no	9.711	9.758	EPSD	TCGA;COSMIC	9.540	Up-regulation
Atypical_PIKK_ATM_ATM_ST	Q14676	MDC1	Q13315	ATM	S1033	D1030N	1030	Missense	distal	-3	no	9.711	9.438	EPSD	TCGA	9.540	Loss
Atypical_PIKK_ATM_ATM_ST	Q14676	MDC1	Q13315	ATM	S1033	D1035A	1035	Missense	proximal	2	no	9.711	8.748	EPSD	TCGA;COSMIC	9.540	Loss
Atypical_PIKK_ATM_ATM_ST	Q14676	MDC1	Q13315	ATM	S1055	Q1056E	1056	Missense	proximal	1	no	14.808	8.911	EPSD	TCGA;COSMIC	9.540	Loss
Atypical_PIKK_ATM_ATM_ST	Q14676	MDC1	Q13315	ATM	S1055	N1054D	1054	Missense	proximal	-1	no	14.808	14.809	EPSD	TCGA;COSMIC	9.540	Up-regulation
Atypical_PIKK_ATM_ATM_ST	Q14676	MDC1	Q13315	ATM	S1057	Q1056E	1056	Missense	proximal	-1	no	13.905	14.183	EPSD	TCGA;COSMIC	9.540	Up-regulation
Atypical_PIKK_ATM_ATM_ST	Q14676	MDC1	Q13315	ATM	S1057	N1054D	1054	Missense	distal	-3	no	13.905	14.178	EPSD	TCGA;COSMIC	9.540	Up-regulation
Atypical_PIKK_ATM_ATM_ST	Q14676	MDC1	Q13315	ATM	S1086	P1093L	1093	Missense	distal	7	no	14.346	14.347	EPSD	TCGA;COSMIC	9.540	Up-regulation
Atypical_PIKK_ATM_ATM_ST	Q14676	MDC1	Q13315	ATM	S1086	Q1087H	1087	Missense	proximal	1	no	14.346	-0.562	EPSD	TCGA;COSMIC	9.540	Loss
Atypical_PIKK_ATM_ATM_ST	Q14676	MDC1	Q13315	ATM	S1143	P1139S	1139	Missense	distal	-4	no	13.606	14.275	EPSD	TCGA;COSMIC	9.540	Up-regulation
Atypical_PIKK_ATM_ATM_ST	Q14676	MDC1	Q13315	ATM	S1143	S1143Y	1143	Missense	central	0	yes	13.606	0.000	EPSD	TCGA	9.540	Loss
Atypical_PIKK_ATM_ATM_ST	Q14676	MDC1	Q13315	ATM	S1184	G1189V	1189	Missense	distal	5	no	13.570	13.604	EPSD	TCGA;COSMIC	9.540	Up-regulation
Atypical_PIKK_ATM_ATM_ST	Q14676	MDC1	Q13315	ATM	T1198	S1194C	1194	Missense	distal	-4	no	10.825	9.252	EPSD	TCGA;ICGC;COSMIC	9.540	Loss
Atypical_PIKK_ATM_ATM_ST	Q14676	MDC1	Q13315	ATM	S1225	Q1226E	1226	Missense	proximal	1	no	13.833	7.936	EPSD	TCGA;COSMIC	9.540	Loss
Atypical_PIKK_ATM_ATM_ST	Q14676	MDC1	Q13315	ATM	S1225	K1232N	1232	Missense	distal	7	no	13.833	13.825	EPSD	TCGA;COSMIC	9.540	Down-regulation
Atypical_PIKK_ATM_ATM_ST	Q14676	MDC1	Q13315	ATM	S1225	G1230E	1230	Missense	distal	5	no	13.833	13.484	EPSD	TCGA	9.540	Down-regulation
Atypical_PIKK_ATM_ATM_ST	Q14676	MDC1	Q13315	ATM	S1225	R1231I	1231	Missense	distal	6	no	13.833	13.810	EPSD	TCGA;COSMIC	9.540	Down-regulation
Atypical_PIKK_ATM_ATM_ST	Q14676	MDC1	Q13315	ATM	T1239	K1232N	1232	Missense	distal	-7	no	10.798	10.924	EPSD	TCGA;COSMIC	9.540	Up-regulation
Atypical_PIKK_ATM_ATM_ST	Q14676	MDC1	Q13315	ATM	S1262	E1263Q	1263	Missense	proximal	1	no	8.267	14.164	EPSD	TCGA;COSMIC	9.540	Gain
Atypical_PIKK_ATM_ATM_ST	Q14676	MDC1	Q13315	ATM	T1280	P1286L	1286	Missense	distal	6	no	10.583	10.538	EPSD	TCGA	9.540	Down-regulation
Atypical_PIKK_ATM_ATM_ST	Q14676	MDC1	Q13315	ATM	S1307	R1308Q	1308	Missense	proximal	1	no	7.159	13.811	EPSD	TCGA;COSMIC	9.540	Gain
Atypical_PIKK_ATM_ATM_ST	Q14676	MDC1	Q13315	ATM	T1321	T1328I	1328	Missense	distal	7	no	10.241	10.256	EPSD	TCGA;COSMIC	9.540	Up-regulation
Atypical_PIKK_ATM_ATM_ST	Q14676	MDC1	Q13315	ATM	T1321	T1321I	1321	Missense	central	0	yes	10.241	0.000	EPSD	TCGA;COSMIC	9.540	Loss
Atypical_PIKK_ATM_ATM_ST	Q14676	MDC1	Q13315	ATM	S1389	R1390Q	1390	Missense	proximal	1	no	6.296	12.948	EPSD	TCGA;COSMIC;GDSC;CCLE	9.540	Gain
Atypical_PIKK_ATM_ATM_ST	Q14676	MDC1	Q13315	ATM	T1403	N1397I	1397	Missense	distal	-6	no	10.104	9.819	EPSD	TCGA;COSMIC	9.540	Down-regulation
Atypical_PIKK_ATM_ATM_ST	Q14676	MDC1	Q13315	ATM	T1403	N1397H	1397	Missense	distal	-6	no	10.104	10.041	EPSD	TCGA;COSMIC	9.540	Down-regulation
Atypical_PIKK_ATM_ATM_ST	Q14676	MDC1	Q13315	ATM	S1430	P1426H	1426	Missense	distal	-4	no	13.024	13.014	EPSD	TCGA;COSMIC	9.540	Down-regulation
Atypical_PIKK_ATM_ATM_ST	Q14676	MDC1	Q13315	ATM	S1430	S1430C	1430	Missense	central	0	yes	13.024	0.000	EPSD	TCGA;COSMIC	9.540	Loss
Atypical_PIKK_ATM_ATM_ST	Q14676	MDC1	Q13315	ATM	S1430	T1425A	1425	Missense	distal	-5	no	13.024	13.106	EPSD	TCGA;COSMIC	9.540	Up-regulation
Atypical_PIKK_ATM_ATM_ST	Q14676	MDC1	Q13315	ATM	S1430	G1435D	1435	Missense	distal	5	no	13.024	12.933	EPSD	TCGA;COSMIC	9.540	Down-regulation
Atypical_PIKK_ATM_ATM_ST	Q14676	MDC1	Q13315	ATM	T1444	T1451A	1451	Missense	distal	7	no	10.398	10.413	EPSD	TCGA;COSMIC	9.540	Up-regulation
Atypical_PIKK_ATM_ATM_ST	Q14676	MDC1	Q13315	ATM	T1444	S1440F	1440	Missense	distal	-4	no	10.398	9.000	EPSD	TCGA;COSMIC	9.540	Loss
Atypical_PIKK_ATM_ATM_ST	Q14676	MDC1	Q13315	ATM	S1471	P1469H	1469	Missense	proximal	-2	no	13.254	13.063	EPSD	TCGA;COSMIC	9.540	Down-regulation
Atypical_PIKK_ATM_ATM_ST	Q14676	MDC1	Q13315	ATM	T1485	R1480I	1480	Missense	distal	-5	no	10.500	10.539	EPSD	TCGA	9.540	Up-regulation
Atypical_PIKK_ATM_ATM_ST	Q14676	MDC1	Q13315	ATM	T1485	R1480K	1480	Missense	distal	-5	no	10.500	10.341	EPSD	TCGA;COSMIC	9.540	Down-regulation
Atypical_PIKK_ATM_ATM_ST	Q14676	MDC1	Q13315	ATM	S1499	D1503H	1503	Missense	distal	4	no	10.190	10.100	EPSD	TCGA;COSMIC	9.540	Down-regulation
Atypical_PIKK_ATM_ATM_ST	Q14676	MDC1	Q13315	ATM	S1512	R1513Q	1513	Missense	proximal	1	no	7.591	14.242	EPSD	TCGA;COSMIC	9.540	Gain
Atypical_PIKK_ATM_ATM_ST	Q14676	MDC1	Q13315	ATM	T1526	R1521Q	1521	Missense	distal	-5	no	10.241	10.031	EPSD	TCGA;COSMIC	9.540	Down-regulation
Atypical_PIKK_ATM_ATM_ST	Q14676	MDC1	Q13315	ATM	T1526	A1533T	1533	Missense	distal	7	no	10.241	10.226	EPSD	TCGA;COSMIC	9.540	Down-regulation
Atypical_PIKK_ATM_ATM_ST	Q14676	MDC1	Q13315	ATM	T1567	R1562K	1562	Missense	distal	-5	no	10.640	10.481	EPSD	TCGA;COSMIC	9.540	Down-regulation
Atypical_PIKK_ATM_ATM_ST	Q14676	MDC1	Q13315	ATM	T1567	K1566N	1566	Missense	proximal	-1	no	10.640	10.778	EPSD	TCGA	9.540	Up-regulation
Atypical_PIKK_ATM_ATM_ST	Q14676	MDC1	Q13315	ATM	T1608	S1605C	1605	Missense	distal	-3	no	10.316	10.483	EPSD	TCGA;COSMIC	9.540	Up-regulation
Atypical_PIKK_ATM_ATM_ST	Q14676	MDC1	Q13315	ATM	T1608	V1606F	1606	Missense	proximal	-2	no	10.316	10.080	EPSD	TCGA	9.540	Down-regulation
Atypical_PIKK_ATM_ATM_ST	Q14676	MDC1	Q13315	ATM	T1608	R1603W	1603	Missense	distal	-5	no	10.316	10.481	EPSD	TCGA;COSMIC	9.540	Up-regulation
Atypical_PIKK_ATM_ATM_ST	Q14676	MDC1	Q13315	ATM	T1716	I1710F	1710	Missense	distal	-6	no	11.815	11.684	EPSD	TCGA;ICGC;COSMIC	9.540	Down-regulation
Atypical_PIKK_ATM_ATM_ST	Q14676	MDC1	Q13315	ATM	T1716	S1711F	1711	Missense	distal	-5	no	11.815	12.138	EPSD	TCGA;ICGC;COSMIC	9.540	Up-regulation
Atypical_PIKK_ATM_ATM_ST	Q14676	MDC1	Q13315	ATM	S1786	H1784Y	1784	Missense	proximal	-2	no	12.057	12.314	EPSD	TCGA;COSMIC	9.540	Up-regulation
Atypical_PIKK_ATM_ATM_ST	Q14676	MDC1	Q13315	ATM	S1820	S1820L	1820	Missense	central	0	yes	9.767	0.000	EPSD	TCGA;ICGC;COSMIC	9.540	Loss
Atypical_PIKK_ATM_ATM_ST	Q14676	MDC1	Q13315	ATM	S1820	M1818V	1818	Missense	proximal	-2	no	9.767	9.541	EPSD	TCGA;ICGC;COSMIC	9.540	Down-regulation
Atypical_PIKK_ATM_ATM_ST	Q14676	MDC1	Q13315	ATM	S1820	P1827S	1827	Missense	distal	7	no	9.767	9.748	EPSD	TCGA;COSMIC	9.540	Down-regulation
Atypical_PIKK_ATM_ATM_ST	Q14676	MDC1	Q13315	ATM	S1833	P1827S	1827	Missense	distal	-6	no	13.180	13.239	EPSD	TCGA;COSMIC	9.540	Up-regulation
Atypical_PIKK_ATM_ATM_ST	Q9H7Z6	KAT8	Q13315	ATM	S348	G347S	347	Missense	proximal	-1	no	10.635	10.827	EPSD	TCGA;ICGC;COSMIC	9.540	Up-regulation
Atypical_PIKK_ATM_ATM_ST	Q9H7Z6	KAT8	Q13315	ATM	S348	E350K	350	Missense	proximal	2	no	10.635	9.305	EPSD	TCGA;ICGC;COSMIC	9.540	Loss
Atypical_PIKK_ATM_ATM_ST	Q9H7Z6	KAT8	Q13315	ATM	S354	G347S	347	Missense	distal	-7	no	9.134	9.646	EPSD	TCGA;ICGC;COSMIC	9.540	Gain
Atypical_PIKK_ATM_ATM_ST	Q14694	USP10	Q13315	ATM	S35	E30D	30	Missense	distal	-5	no	9.580	9.534	EPSD	TCGA;COSMIC	9.540	Loss
Atypical_PIKK_ATM_ATM_ST	Q14694	USP10	Q13315	ATM	T42	D46N	46	Missense	distal	4	no	12.288	12.208	PhosphoSitePlus;EPSD	TCGA;COSMIC	9.540	Down-regulation
Atypical_PIKK_ATM_ATM_ST	Q14694	USP10	Q13315	ATM	T74	L71F	71	Missense	distal	-3	no	11.682	12.544	EPSD	TCGA;ICGC;COSMIC	9.540	Up-regulation
Atypical_PIKK_ATM_ATM_ST	Q14694	USP10	Q13315	ATM	S76	L71F	71	Missense	distal	-5	no	9.841	10.141	EPSD	TCGA;ICGC;COSMIC	9.540	Up-regulation
Atypical_PIKK_ATM_ATM_ST	Q14694	USP10	Q13315	ATM	S76	L83P	83	Missense	distal	7	no	9.841	9.840	EPSD	TCGA;COSMIC	9.540	Down-regulation
Atypical_PIKK_ATM_ATM_ST	Q14694	USP10	Q13315	ATM	S211	P206L	206	Missense	distal	-5	no	9.560	9.579	EPSD	TCGA;COSMIC	9.540	Up-regulation
Atypical_PIKK_ATM_ATM_ST	Q14694	USP10	Q13315	ATM	S211	S215F	215	Missense	distal	4	no	9.560	10.387	EPSD	TCGA;COSMIC	9.540	Up-regulation
Atypical_PIKK_ATM_ATM_ST	Q14694	USP10	Q13315	ATM	S321	D325G	325	Missense	distal	4	no	10.326	10.247	EPSD	TCGA;ICGC;COSMIC	9.540	Down-regulation
Atypical_PIKK_ATM_ATM_ST	Q14694	USP10	Q13315	ATM	S321	E318K	318	Missense	distal	-3	no	10.326	10.393	EPSD	TCGA;ICGC;COSMIC	9.540	Up-regulation
Atypical_PIKK_ATM_ATM_ST	Q14694	USP10	Q13315	ATM	S331	D325G	325	Missense	distal	-6	no	10.845	10.670	EPSD	TCGA;ICGC;COSMIC	9.540	Down-regulation
Atypical_PIKK_ATM_ATM_ST	Q14694	USP10	Q13315	ATM	S516	G519S	519	Missense	distal	3	no	9.556	9.425	EPSD	TCGA	9.540	Loss
Atypical_PIKK_ATM_ATM_ST	Q14694	USP10	Q13315	ATM	S670	R671Q	671	Missense	proximal	1	no	11.861	18.513	EPSD	TCGA;COSMIC	9.540	Up-regulation
Atypical_PIKK_ATM_ATM_ST	Q14694	USP10	Q13315	ATM	S670	L675V	675	Missense	distal	5	no	11.861	11.909	EPSD	TCGA;COSMIC	9.540	Up-regulation
Atypical_PIKK_ATM_ATM_ST	Q09472	EP300	Q13315	ATM	S20	K14Q	14	Missense	distal	-6	no	9.820	9.897	EPSD	TCGA;ICGC;COSMIC	9.540	Up-regulation
Atypical_PIKK_ATM_ATM_ST	Q09472	EP300	Q13315	ATM	S20	K17E	17	Missense	distal	-3	no	9.820	9.753	EPSD	TCGA;ICGC;COSMIC	9.540	Down-regulation
Atypical_PIKK_ATM_ATM_ST	Q09472	EP300	Q13315	ATM	S20	A25P	25	Missense	distal	5	no	9.820	9.954	EPSD	TCGA;ICGC;COSMIC	9.540	Up-regulation
Atypical_PIKK_ATM_ATM_ST	Q09472	EP300	Q13315	ATM	S20	P21A	21	Missense	proximal	1	no	9.820	7.749	EPSD	TCGA;ICGC;COSMIC	9.540	Loss
Atypical_PIKK_ATM_ATM_ST	Q09472	EP300	Q13315	ATM	S24	A25P	25	Missense	proximal	1	no	8.542	10.614	EPSD	TCGA;ICGC;COSMIC	9.540	Gain
Atypical_PIKK_ATM_ATM_ST	Q09472	EP300	Q13315	ATM	S26	A25P	25	Missense	proximal	-1	no	10.301	10.169	EPSD	TCGA;ICGC;COSMIC	9.540	Down-regulation
Atypical_PIKK_ATM_ATM_ST	Q09472	EP300	Q13315	ATM	S26	P21A	21	Missense	distal	-5	no	10.301	10.290	EPSD	TCGA;ICGC;COSMIC	9.540	Down-regulation
Atypical_PIKK_ATM_ATM_ST	Q09472	EP300	Q13315	ATM	S26	F33V	33	Missense	distal	7	no	10.301	10.289	EPSD	TCGA;ICGC;COSMIC	9.540	Down-regulation
Atypical_PIKK_ATM_ATM_ST	Q09472	EP300	Q13315	ATM	S106	V103G	103	Missense	distal	-3	no	15.018	14.878	PhosphoSitePlus	TCGA;ICGC	9.540	Down-regulation
Atypical_PIKK_ATM_ATM_ST	Q09472	EP300	Q13315	ATM	S112	G114E	114	Missense	proximal	2	no	8.263	9.632	EPSD	TCGA;ICGC	9.540	Gain
Atypical_PIKK_ATM_ATM_ST	Q09472	EP300	Q13315	ATM	S255	Y257D	257	Missense	proximal	2	no	9.359	10.600	EPSD	TCGA;ICGC;COSMIC	9.540	Gain
Atypical_PIKK_ATM_ATM_ST	Q09472	EP300	Q13315	ATM	S255	T258I	258	Missense	distal	3	no	9.359	9.780	EPSD	TCGA;ICGC	9.540	Gain
Atypical_PIKK_ATM_ATM_ST	Q09472	EP300	Q13315	ATM	T258	Y257D	257	Missense	proximal	-1	no	12.150	12.144	EPSD	TCGA;ICGC;COSMIC	9.540	Down-regulation
Atypical_PIKK_ATM_ATM_ST	Q09472	EP300	Q13315	ATM	T258	T258I	258	Missense	central	0	yes	12.150	0.000	EPSD	TCGA;ICGC	9.540	Loss
Atypical_PIKK_ATM_ATM_ST	Q09472	EP300	Q13315	ATM	S384	A391T	391	Missense	distal	7	no	9.803	9.789	EPSD	TCGA;ICGC;COSMIC	9.540	Down-regulation
Atypical_PIKK_ATM_ATM_ST	Q09472	EP300	Q13315	ATM	S831	H828Y	828	Missense	distal	-3	no	9.885	9.923	EPSD	TCGA;ICGC;COSMIC	9.540	Up-regulation
Atypical_PIKK_ATM_ATM_ST	Q09472	EP300	Q13315	ATM	S831	S833L	833	Missense	proximal	2	no	9.885	8.642	EPSD	TCGA;ICGC;COSMIC	9.540	Loss
Atypical_PIKK_ATM_ATM_ST	Q09472	EP300	Q13315	ATM	T1012	S1009Y	1009	Missense	distal	-3	no	9.427	9.560	EPSD	TCGA;ICGC;COSMIC	9.540	Gain
Atypical_PIKK_ATM_ATM_ST	Q09472	EP300	Q13315	ATM	T1035	P1039L	1039	Missense	distal	4	no	14.535	14.754	EPSD	TCGA;ICGC;COSMIC	9.540	Up-regulation
Atypical_PIKK_ATM_ATM_ST	Q09472	EP300	Q13315	ATM	S1038	P1039L	1039	Missense	proximal	1	no	11.552	9.998	EPSD	TCGA;ICGC;COSMIC	9.540	Down-regulation
Atypical_PIKK_ATM_ATM_ST	Q09472	EP300	Q13315	ATM	S1038	K1045N	1045	Missense	distal	7	no	11.552	11.544	EPSD	TCGA;ICGC;COSMIC;CCLE	9.540	Down-regulation
Atypical_PIKK_ATM_ATM_ST	Q09472	EP300	Q13315	ATM	S1072	P1074S	1074	Missense	proximal	2	no	9.184	9.639	EPSD	TCGA;ICGC;COSMIC	9.540	Gain
Atypical_PIKK_ATM_ATM_ST	Q09472	EP300	Q13315	ATM	S1220	Q1223E	1223	Missense	distal	3	no	15.159	14.900	EPSD	TCGA;ICGC;COSMIC	9.540	Down-regulation
Atypical_PIKK_ATM_ATM_ST	Q09472	EP300	Q13315	ATM	S1220	S1214Y	1214	Missense	distal	-6	no	15.159	14.910	EPSD	TCGA;COSMIC;CCLE	9.540	Down-regulation
Atypical_PIKK_ATM_ATM_ST	Q09472	EP300	Q13315	ATM	S1220	S1214F	1214	Missense	distal	-6	no	15.159	14.628	EPSD	TCGA;ICGC;COSMIC	9.540	Down-regulation
Atypical_PIKK_ATM_ATM_ST	Q09472	EP300	Q13315	ATM	S1220	V1213I	1213	Missense	distal	-7	no	15.159	14.975	EPSD	TCGA;ICGC;COSMIC	9.540	Down-regulation
Atypical_PIKK_ATM_ATM_ST	Q09472	EP300	Q13315	ATM	S1220	T1224A	1224	Missense	distal	4	no	15.159	14.724	EPSD	TCGA;ICGC;COSMIC	9.540	Down-regulation
Atypical_PIKK_ATM_ATM_ST	Q09472	EP300	Q13315	ATM	S1581	S1577F	1577	Missense	distal	-4	no	14.540	13.141	EPSD	TCGA;ICGC;COSMIC	9.540	Down-regulation
Atypical_PIKK_ATM_ATM_ST	Q09472	EP300	Q13315	ATM	S1581	S1581L	1581	Missense	central	0	yes	14.540	0.000	EPSD	TCGA;ICGC;COSMIC	9.540	Loss
Atypical_PIKK_ATM_ATM_ST	Q09472	EP300	Q13315	ATM	S1581	L1584P	1584	Missense	distal	3	no	14.540	14.410	EPSD	TCGA;ICGC;COSMIC	9.540	Down-regulation
Atypical_PIKK_ATM_ATM_ST	Q09472	EP300	Q13315	ATM	S1897	Q1904P	1904	Missense	distal	7	no	12.874	12.883	EPSD	TCGA;ICGC;COSMIC	9.540	Up-regulation
Atypical_PIKK_ATM_ATM_ST	Q09472	EP300	Q13315	ATM	S1897	A1901V	1901	Missense	distal	4	no	12.874	13.527	EPSD	TCGA;ICGC;COSMIC	9.540	Up-regulation
Atypical_PIKK_ATM_ATM_ST	Q09472	EP300	Q13315	ATM	S2320	R2317Q	2317	Missense	distal	-3	no	14.307	13.532	EPSD	TCGA;ICGC;COSMIC	9.540	Down-regulation
Atypical_PIKK_ATM_ATM_ST	Q09472	EP300	Q13315	ATM	S2320	P2327H	2327	Missense	distal	7	no	14.307	14.317	EPSD	TCGA;ICGC	9.540	Up-regulation
Atypical_PIKK_ATM_ATM_ST	Q09472	EP300	Q13315	ATM	S2320	R2317L	2317	Missense	distal	-3	no	14.307	13.776	EPSD	TCGA;ICGC;COSMIC	9.540	Down-regulation
Atypical_PIKK_ATM_ATM_ST	Q92878	RAD50	Q13315	ATM	T198	R196C	196	Missense	proximal	-2	no	11.334	11.314	EPSD	TCGA	9.540	Down-regulation
Atypical_PIKK_ATM_ATM_ST	Q92878	RAD50	Q13315	ATM	T536	R535H	535	Missense	proximal	-1	no	11.201	11.371	EPSD	TCGA;COSMIC;GDSC;CCLE	9.540	Up-regulation
Atypical_PIKK_ATM_ATM_ST	Q92878	RAD50	Q13315	ATM	T536	K543R	543	Missense	distal	7	no	11.201	11.213	EPSD	TCGA;COSMIC	9.540	Up-regulation
Atypical_PIKK_ATM_ATM_ST	Q92878	RAD50	Q13315	ATM	S635	G634C	634	Missense	proximal	-1	no	14.965	14.957	PhosphoSitePlus	TCGA;COSMIC	9.540	Down-regulation
Atypical_PIKK_ATM_ATM_ST	Q92878	RAD50	Q13315	ATM	S1297	E1298Q	1298	Missense	proximal	1	no	9.876	15.772	EPSD	TCGA;COSMIC	9.540	Up-regulation
Atypical_PIKK_ATM_ATM_ST	Q13263	TRIM28	Q13315	ATM	S223	C224R	224	Missense	proximal	1	no	5.244	10.803	EPSD	TCGA;COSMIC	9.540	Gain
Atypical_PIKK_ATM_ATM_ST	Q13263	TRIM28	Q13315	ATM	S440	S437C	437	Missense	distal	-3	no	14.621	14.789	EPSD	TCGA;ICGC;COSMIC	9.540	Up-regulation
Atypical_PIKK_ATM_ATM_ST	Q13263	TRIM28	Q13315	ATM	S440	S439R	439	Missense	proximal	-1	no	14.621	14.247	EPSD	TCGA;COSMIC	9.540	Down-regulation
Atypical_PIKK_ATM_ATM_ST	Q13263	TRIM28	Q13315	ATM	S440	M443I	443	Missense	distal	3	no	14.621	14.866	EPSD	TCGA;ICGC;COSMIC	9.540	Up-regulation
Atypical_PIKK_ATM_ATM_ST	Q13263	TRIM28	Q13315	ATM	S460	S459T	459	Missense	proximal	-1	no	10.071	10.082	EPSD	TCGA;ICGC	9.540	Up-regulation
Atypical_PIKK_ATM_ATM_ST	Q13263	TRIM28	Q13315	ATM	S501	D496N	496	Missense	distal	-5	no	14.167	14.350	EPSD	TCGA;ICGC	9.540	Up-regulation
Atypical_PIKK_ATM_ATM_ST	Q13263	TRIM28	Q13315	ATM	S501	V508L	508	Missense	distal	7	no	14.167	14.138	EPSD	TCGA;ICGC;COSMIC	9.540	Down-regulation
Atypical_PIKK_ATM_ATM_ST	Q13263	TRIM28	Q13315	ATM	S501	V508D	508	Missense	distal	7	no	14.167	14.127	EPSD	TCGA	9.540	Down-regulation
Atypical_PIKK_ATM_ATM_ST	Q13263	TRIM28	Q13315	ATM	S594	P590S	590	Missense	distal	-4	no	10.834	11.503	EPSD	TCGA;ICGC;COSMIC	9.540	Up-regulation
Atypical_PIKK_ATM_ATM_ST	Q13263	TRIM28	Q13315	ATM	S594	A587V	587	Missense	distal	-7	no	10.834	10.451	EPSD	TCGA;ICGC;COSMIC	9.540	Down-regulation
Atypical_PIKK_ATM_ATM_ST	Q13263	TRIM28	Q13315	ATM	S594	S598G	598	Missense	distal	4	no	10.834	10.963	EPSD	TCGA	9.540	Up-regulation
Atypical_PIKK_ATM_ATM_ST	Q13263	TRIM28	Q13315	ATM	S594	R591H	591	Missense	distal	-3	no	10.834	10.189	EPSD	TCGA;ICGC	9.540	Down-regulation
Atypical_PIKK_ATM_ATM_ST	Q13263	TRIM28	Q13315	ATM	S757	Y755C	755	Missense	proximal	-2	no	9.585	9.292	EPSD	TCGA;ICGC;COSMIC	9.540	Loss
Atypical_PIKK_ATM_ATM_ST	Q13263	TRIM28	Q13315	ATM	S824	S823I	823	Missense	proximal	-1	no	15.344	15.123	PhosphoSitePlus	TCGA;ICGC	9.540	Down-regulation
Atypical_PIKK_ATM_ATM_ST	Q13263	TRIM28	Q13315	ATM	S828	S823I	823	Missense	distal	-5	no	9.840	9.954	EPSD	TCGA;ICGC	9.540	Up-regulation
Atypical_PIKK_ATM_ATM_ST	Q15910	EZH2	Q13315	ATM	S212	R216Q	216	Missense	distal	4	no	10.255	10.106	EPSD	TCGA;COSMIC	9.540	Down-regulation
Atypical_PIKK_ATM_ATM_ST	Q15910	EZH2	Q13315	ATM	S212	D208Y	208	Missense	distal	-4	no	10.255	9.158	EPSD	TCGA	9.540	Loss
Atypical_PIKK_ATM_ATM_ST	Q15910	EZH2	Q13315	ATM	S212	R207Q	207	Missense	distal	-5	no	10.255	10.045	EPSD	TCGA;ICGC;COSMIC	9.540	Down-regulation
Atypical_PIKK_ATM_ATM_ST	Q15910	EZH2	Q13315	ATM	S277	S271Y	271	Missense	distal	-6	no	9.721	9.472	EPSD	TCGA;COSMIC	9.540	Loss
Atypical_PIKK_ATM_ATM_ST	O15151	MDM4	Q13315	ATM	S20	Q26E	26	Missense	distal	6	no	11.562	11.609	EPSD	TCGA;ICGC;COSMIC	9.540	Up-regulation
Atypical_PIKK_ATM_ATM_ST	O15151	MDM4	Q13315	ATM	S20	R18S	18	Missense	proximal	-2	no	11.562	12.005	EPSD	TCGA;ICGC	9.540	Up-regulation
Atypical_PIKK_ATM_ATM_ST	O15151	MDM4	Q13315	ATM	S264	Q262H	262	Missense	proximal	-2	no	12.206	11.903	EPSD	TCGA;ICGC;COSMIC	9.540	Down-regulation
Atypical_PIKK_ATM_ATM_ST	O15151	MDM4	Q13315	ATM	S264	A257V	257	Missense	distal	-7	no	12.206	11.822	EPSD	TCGA;ICGC;COSMIC	9.540	Down-regulation
Atypical_PIKK_ATM_ATM_ST	O15151	MDM4	Q13315	ATM	S264	T260I	260	Missense	distal	-4	no	12.206	11.878	EPSD	TCGA;ICGC;COSMIC	9.540	Down-regulation
Atypical_PIKK_ATM_ATM_ST	O15151	MDM4	Q13315	ATM	S291	S287C	287	Missense	distal	-4	no	9.939	8.366	EPSD	TCGA;ICGC;COSMIC	9.540	Loss
Atypical_PIKK_ATM_ATM_ST	O15151	MDM4	Q13315	ATM	S344	T338P	338	Missense	distal	-6	no	10.085	10.095	EPSD	TCGA;COSMIC	9.540	Up-regulation
Atypical_PIKK_ATM_ATM_ST	O15151	MDM4	Q13315	ATM	S403	E405D	405	Missense	proximal	2	no	15.294	15.164	PhosphoSitePlus	TCGA;ICGC;COSMIC	9.540	Down-regulation
Atypical_PIKK_ATM_ATM_ST	Q9H9Q4	NHEJ1	Q13315	ATM	S55	K59N	59	Missense	distal	4	no	12.475	12.522	EPSD	TCGA;ICGC	9.540	Up-regulation
Atypical_PIKK_ATM_ATM_ST	Q9H9Q4	NHEJ1	Q13315	ATM	T223	Q230H	230	Missense	distal	7	no	10.358	10.376	EPSD	TCGA;ICGC;COSMIC	9.540	Up-regulation
Atypical_PIKK_ATM_ATM_ST	Q9H9Q4	NHEJ1	Q13315	ATM	T223	G229R	229	Missense	distal	6	no	10.358	10.359	EPSD	TCGA;ICGC;COSMIC	9.540	Up-regulation
Atypical_PIKK_ATM_ATM_ST	Q14191	WRN	Q13315	ATM	S248	D249N	249	Missense	proximal	1	no	9.686	5.856	EPSD	TCGA;ICGC;COSMIC	9.540	Loss
Atypical_PIKK_ATM_ATM_ST	Q14191	WRN	Q13315	ATM	S409	L405V	405	Missense	distal	-4	no	15.058	15.008	EPSD	TCGA;ICGC;COSMIC	9.540	Down-regulation
Atypical_PIKK_ATM_ATM_ST	Q14191	WRN	Q13315	ATM	S440	Y436C	436	Missense	distal	-4	no	10.013	9.541	EPSD	TCGA;ICGC;COSMIC	9.540	Down-regulation
Atypical_PIKK_ATM_ATM_ST	Q14191	WRN	Q13315	ATM	S478	E480D	480	Missense	proximal	2	no	10.713	10.582	EPSD	TCGA;ICGC	9.540	Down-regulation
Atypical_PIKK_ATM_ATM_ST	Q14191	WRN	Q13315	ATM	S478	S484R	484	Missense	distal	6	no	10.713	10.695	EPSD	TCGA;ICGC;COSMIC	9.540	Down-regulation
Atypical_PIKK_ATM_ATM_ST	Q14191	WRN	Q13315	ATM	S863	C864Y	864	Missense	proximal	1	no	3.851	10.345	EPSD	TCGA;ICGC;COSMIC;CCLE	9.540	Gain
Atypical_PIKK_ATM_ATM_ST	Q14191	WRN	Q13315	ATM	S1058	L1063F	1063	Missense	distal	5	no	15.586	15.728	EPSD	TCGA;ICGC;COSMIC	9.540	Up-regulation
Atypical_PIKK_ATM_ATM_ST	Q14191	WRN	Q13315	ATM	S1139	S1140P	1140	Missense	proximal	1	no	6.843	13.818	EPSD	TCGA;ICGC;COSMIC	9.540	Gain
Atypical_PIKK_ATM_ATM_ST	Q14191	WRN	Q13315	ATM	S1141	S1140P	1140	Missense	proximal	-1	no	16.725	16.433	PhosphoSitePlus	TCGA;ICGC;COSMIC	9.540	Down-regulation
Atypical_PIKK_ATM_ATM_ST	Q14191	WRN	Q13315	ATM	S1292	S1292F	1292	Missense	central	0	yes	14.612	0.000	EPSD	TCGA;ICGC;COSMIC	9.540	Loss
Atypical_PIKK_ATM_ATM_ST	Q14191	WRN	Q13315	ATM	S1292	A1294V	1294	Missense	proximal	2	no	14.612	14.303	EPSD	TCGA;ICGC;COSMIC	9.540	Down-regulation
Atypical_PIKK_ATM_ATM_ST	Q14191	WRN	Q13315	ATM	S1378	S1378F	1378	Missense	central	0	yes	10.599	0.000	EPSD	TCGA;ICGC;COSMIC	9.540	Loss
Atypical_PIKK_ATM_ATM_ST	Q14191	WRN	Q13315	ATM	S1378	R1373I	1373	Missense	distal	-5	no	10.599	10.637	EPSD	TCGA;ICGC;COSMIC	9.540	Up-regulation
Atypical_PIKK_ATM_ATM_ST	Q13362	PPP2R5C	Q13315	ATM	S520	D516H	516	Missense	distal	-4	no	14.823	14.147	PhosphoSitePlus	TCGA;COSMIC	9.540	Down-regulation
Atypical_PIKK_ATM_ATM_ST	Q14674	ESPL1	Q13315	ATM	S810	R805I	805	Missense	distal	-5	no	9.715	9.753	EPSD	TCGA;ICGC;COSMIC	9.540	Up-regulation
Atypical_PIKK_ATM_ATM_ST	Q14674	ESPL1	Q13315	ATM	S810	S810L	810	Missense	central	0	yes	9.715	0.000	EPSD	TCGA;ICGC;COSMIC	9.540	Loss
Atypical_PIKK_ATM_ATM_ST	Q14674	ESPL1	Q13315	ATM	S1308	P1303T	1303	Missense	distal	-5	no	9.678	9.585	EPSD	TCGA;ICGC;COSMIC	9.540	Down-regulation
Atypical_PIKK_ATM_ATM_ST	Q14674	ESPL1	Q13315	ATM	S1406	D1403N	1403	Missense	distal	-3	no	9.671	9.398	EPSD	TCGA;ICGC;COSMIC	9.540	Loss
Atypical_PIKK_ATM_ATM_ST	Q14674	ESPL1	Q13315	ATM	S1641	R1647Q	1647	Missense	distal	6	no	9.708	9.704	EPSD	TCGA;ICGC;COSMIC	9.540	Down-regulation
Atypical_PIKK_ATM_ATM_ST	Q14674	ESPL1	Q13315	ATM	S1641	L1640F	1640	Missense	proximal	-1	no	9.708	9.417	EPSD	TCGA;ICGC;COSMIC	9.540	Loss
Atypical_PIKK_ATM_ATM_ST	Q14674	ESPL1	Q13315	ATM	S1641	H1635Y	1635	Missense	distal	-6	no	9.708	9.638	EPSD	TCGA;ICGC;COSMIC	9.540	Down-regulation
Atypical_PIKK_ATM_ATM_ST	Q9UER7	DAXX	Q13315	ATM	S176	E172K	172	Missense	distal	-4	no	14.524	13.552	EPSD	TCGA;ICGC;COSMIC;CCLE	9.540	Down-regulation
Atypical_PIKK_ATM_ATM_ST	Q9UER7	DAXX	Q13315	ATM	S176	S176C	176	Missense	central	0	yes	14.524	0.000	EPSD	TCGA;ICGC;COSMIC	9.540	Loss
Atypical_PIKK_ATM_ATM_ST	Q9UER7	DAXX	Q13315	ATM	S176	R180M	180	Missense	distal	4	no	14.524	14.603	EPSD	TCGA;ICGC	9.540	Up-regulation
Atypical_PIKK_ATM_ATM_ST	Q9UER7	DAXX	Q13315	ATM	S176	A175T	175	Missense	proximal	-1	no	14.524	14.695	EPSD	TCGA;ICGC	9.540	Up-regulation
Atypical_PIKK_ATM_ATM_ST	Q9UER7	DAXX	Q13315	ATM	S403	H404Y	404	Missense	proximal	1	no	1.433	10.626	EPSD	TCGA;ICGC;COSMIC	9.540	Gain
Atypical_PIKK_ATM_ATM_ST	Q9UER7	DAXX	Q13315	ATM	S412	S415F	415	Missense	distal	3	no	9.089	9.671	EPSD	TCGA;ICGC;COSMIC	9.540	Gain
Atypical_PIKK_ATM_ATM_ST	Q9UER7	DAXX	Q13315	ATM	S424	G421E	421	Missense	distal	-3	no	15.255	14.817	EPSD	TCGA;ICGC;COSMIC	9.540	Down-regulation
Atypical_PIKK_ATM_ATM_ST	Q9UER7	DAXX	Q13315	ATM	S495	S495N	495	Missense	central	0	yes	9.857	0.000	EPSD	TCGA;ICGC	9.540	Loss
Atypical_PIKK_ATM_ATM_ST	Q9UER7	DAXX	Q13315	ATM	S499	S495N	495	Missense	distal	-4	no	10.162	9.234	EPSD	TCGA;ICGC	9.540	Loss
Atypical_PIKK_ATM_ATM_ST	Q9UER7	DAXX	Q13315	ATM	S564	L566F	566	Missense	proximal	2	no	13.924	13.689	PhosphoSitePlus	TCGA;ICGC;COSMIC	9.540	Down-regulation
Atypical_PIKK_ATM_ATM_ST	Q9UER7	DAXX	Q13315	ATM	S564	P562L	562	Missense	proximal	-2	no	13.924	13.771	PhosphoSitePlus	TCGA;ICGC;COSMIC	9.540	Down-regulation
Atypical_PIKK_ATM_ATM_ST	Q9UER7	DAXX	Q13315	ATM	S593	S588F	588	Missense	distal	-5	no	9.763	10.087	EPSD	TCGA;ICGC;COSMIC;CCLE	9.540	Up-regulation
Atypical_PIKK_ATM_ATM_ST	Q9UER7	DAXX	Q13315	ATM	S593	S587P	587	Missense	distal	-6	no	9.763	9.704	EPSD	TCGA;ICGC;COSMIC	9.540	Down-regulation
Atypical_PIKK_ATM_ATM_ST	Q9UER7	DAXX	Q13315	ATM	S593	S588Y	588	Missense	distal	-5	no	9.763	9.787	EPSD	TCGA;ICGC;COSMIC	9.540	Up-regulation
Atypical_PIKK_ATM_ATM_ST	Q9UER7	DAXX	Q13315	ATM	S593	S587F	587	Missense	distal	-6	no	9.763	9.232	EPSD	TCGA;ICGC;COSMIC	9.540	Loss
Atypical_PIKK_ATM_ATM_ST	Q9UER7	DAXX	Q13315	ATM	S618	S612T	612	Missense	distal	-6	no	9.733	9.663	EPSD	TCGA;ICGC	9.540	Down-regulation
Atypical_PIKK_ATM_ATM_ST	Q9UER7	DAXX	Q13315	ATM	S668	S671F	671	Missense	distal	3	no	9.356	9.938	EPSD	TCGA;ICGC;COSMIC	9.540	Gain
Atypical_PIKK_ATM_ATM_ST	Q9UER7	DAXX	Q13315	ATM	S675	S671F	671	Missense	distal	-4	no	11.103	9.704	EPSD	TCGA;ICGC;COSMIC	9.540	Down-regulation
Atypical_PIKK_ATM_ATM_ST	Q9UER7	DAXX	Q13315	ATM	S675	S682C	682	Missense	distal	7	no	11.103	11.155	EPSD	TCGA;ICGC;COSMIC	9.540	Up-regulation
Atypical_PIKK_ATM_ATM_ST	Q9UER7	DAXX	Q13315	ATM	S688	S682C	682	Missense	distal	-6	no	9.994	9.614	EPSD	TCGA;ICGC;COSMIC	9.540	Down-regulation
Atypical_PIKK_ATM_ATM_ST	Q9UER7	DAXX	Q13315	ATM	S688	R685M	685	Missense	distal	-3	no	9.994	9.609	EPSD	TCGA;ICGC	9.540	Down-regulation
Atypical_PIKK_ATM_ATM_ST	Q9UER7	DAXX	Q13315	ATM	S707	P701L	701	Missense	distal	-6	no	11.319	11.090	EPSD	TCGA;ICGC;COSMIC	9.540	Down-regulation
Atypical_PIKK_ATM_ATM_ST	Q9UER7	DAXX	Q13315	ATM	S707	S702F	702	Missense	distal	-5	no	11.319	11.643	EPSD	TCGA;ICGC;COSMIC	9.540	Up-regulation
Atypical_PIKK_ATM_ATM_ST	Q9UER7	DAXX	Q13315	ATM	T726	D729N	729	Missense	distal	3	no	12.260	12.277	EPSD	TCGA;ICGC;COSMIC	9.540	Up-regulation
Atypical_PIKK_ATM_ATM_ST	Q9UER7	DAXX	Q13315	ATM	S737	D738H	738	Missense	proximal	1	no	10.480	1.602	EPSD	TCGA;ICGC;COSMIC	9.540	Loss
Atypical_PIKK_ATM_ATM_ST	Q9UER7	DAXX	Q13315	ATM	S737	S739F	739	Missense	proximal	2	no	10.480	9.001	EPSD	TCGA;ICGC;COSMIC	9.540	Loss
Atypical_PIKK_ATM_ATM_ST	Q9UER7	DAXX	Q13315	ATM	S737	V735M	735	Missense	proximal	-2	no	10.480	10.706	EPSD	TCGA;ICGC;COSMIC	9.540	Up-regulation
Atypical_PIKK_ATM_ATM_ST	Q9UER7	DAXX	Q13315	ATM	S739	D738H	738	Missense	proximal	-1	no	10.772	10.622	EPSD	TCGA;ICGC;COSMIC	9.540	Down-regulation
Atypical_PIKK_ATM_ATM_ST	Q9UER7	DAXX	Q13315	ATM	S739	S739F	739	Missense	central	0	yes	10.772	0.000	EPSD	TCGA;ICGC;COSMIC	9.540	Loss
Atypical_PIKK_ATM_ATM_ST	Q9UER7	DAXX	Q13315	ATM	S739	V735M	735	Missense	distal	-4	no	10.772	10.753	EPSD	TCGA;ICGC;COSMIC	9.540	Down-regulation
Atypical_PIKK_ATM_ATM_ST	Q5UIP0	RIF1	Q13315	ATM	S111	T107I	107	Missense	distal	-4	no	9.942	9.614	EPSD	TCGA;ICGC;COSMIC	9.540	Down-regulation
Atypical_PIKK_ATM_ATM_ST	Q5UIP0	RIF1	Q13315	ATM	S111	V115A	115	Missense	distal	4	no	9.942	9.289	EPSD	TCGA;ICGC;COSMIC	9.540	Loss
Atypical_PIKK_ATM_ATM_ST	Q5UIP0	RIF1	Q13315	ATM	S402	T409N	409	Missense	distal	7	no	9.586	9.584	EPSD	TCGA;ICGC;COSMIC	9.540	Down-regulation
Atypical_PIKK_ATM_ATM_ST	Q5UIP0	RIF1	Q13315	ATM	S467	F470L	470	Missense	distal	3	no	12.329	12.029	EPSD	TCGA;ICGC;COSMIC	9.540	Down-regulation
Atypical_PIKK_ATM_ATM_ST	Q5UIP0	RIF1	Q13315	ATM	S467	P463S	463	Missense	distal	-4	no	12.329	12.998	EPSD	TCGA;ICGC;COSMIC	9.540	Up-regulation
Atypical_PIKK_ATM_ATM_ST	Q5UIP0	RIF1	Q13315	ATM	S467	P463L	463	Missense	distal	-4	no	12.329	12.059	EPSD	TCGA;ICGC;COSMIC	9.540	Down-regulation
Atypical_PIKK_ATM_ATM_ST	Q5UIP0	RIF1	Q13315	ATM	S1089	Q1090H	1090	Missense	proximal	1	no	14.947	0.038	EPSD	TCGA;ICGC;COSMIC	9.540	Loss
Atypical_PIKK_ATM_ATM_ST	Q5UIP0	RIF1	Q13315	ATM	S1089	M1082L	1082	Missense	distal	-7	no	14.947	14.834	EPSD	TCGA;ICGC;COSMIC	9.540	Down-regulation
Atypical_PIKK_ATM_ATM_ST	Q5UIP0	RIF1	Q13315	ATM	S1089	L1086R	1086	Missense	distal	-3	no	14.947	15.478	EPSD	TCGA;ICGC;COSMIC	9.540	Up-regulation
Atypical_PIKK_ATM_ATM_ST	Q5UIP0	RIF1	Q13315	ATM	S1089	S1089A	1089	Missense	central	0	yes	14.947	0.000	EPSD	TCGA;ICGC	9.540	Loss
Atypical_PIKK_ATM_ATM_ST	Q5UIP0	RIF1	Q13315	ATM	S1098	M1103I	1103	Missense	distal	5	no	14.061	14.085	EPSD	TCGA;ICGC;COSMIC	9.540	Up-regulation
Atypical_PIKK_ATM_ATM_ST	Q5UIP0	RIF1	Q13315	ATM	S1098	E1104K	1104	Missense	distal	6	no	14.061	14.015	EPSD	TCGA;ICGC;COSMIC	9.540	Down-regulation
Atypical_PIKK_ATM_ATM_ST	Q5UIP0	RIF1	Q13315	ATM	S1098	S1098N	1098	Missense	central	0	yes	14.061	0.000	EPSD	TCGA;ICGC;COSMIC	9.540	Loss
Atypical_PIKK_ATM_ATM_ST	Q5UIP0	RIF1	Q13315	ATM	S1162	D1159N	1159	Missense	distal	-3	no	11.945	11.672	EPSD	TCGA;ICGC;COSMIC	9.540	Down-regulation
Atypical_PIKK_ATM_ATM_ST	Q5UIP0	RIF1	Q13315	ATM	S1403	I1407R	1407	Missense	distal	4	no	14.271	13.790	EPSD	TCGA;ICGC;COSMIC	9.540	Down-regulation
Atypical_PIKK_ATM_ATM_ST	Q5UIP0	RIF1	Q13315	ATM	S1403	V1399A	1399	Missense	distal	-4	no	14.271	14.750	EPSD	TCGA;ICGC	9.540	Up-regulation
Atypical_PIKK_ATM_ATM_ST	Q5UIP0	RIF1	Q13315	ATM	S1431	S1431N	1431	Missense	central	0	yes	13.958	0.000	EPSD	TCGA;ICGC;COSMIC	9.540	Loss
Atypical_PIKK_ATM_ATM_ST	Q5UIP0	RIF1	Q13315	ATM	S1431	D1433Y	1433	Missense	proximal	2	no	13.958	12.717	EPSD	TCGA;ICGC;COSMIC	9.540	Down-regulation
Atypical_PIKK_ATM_ATM_ST	Q5UIP0	RIF1	Q13315	ATM	S1431	N1436T	1436	Missense	distal	5	no	13.958	13.966	EPSD	TCGA;ICGC;COSMIC	9.540	Up-regulation
Atypical_PIKK_ATM_ATM_ST	Q5UIP0	RIF1	Q13315	ATM	S1454	D1460H	1460	Missense	distal	6	no	11.088	11.077	EPSD	TCGA;ICGC;COSMIC	9.540	Down-regulation
Atypical_PIKK_ATM_ATM_ST	Q5UIP0	RIF1	Q13315	ATM	S1454	L1451F	1451	Missense	distal	-3	no	11.088	11.951	EPSD	TCGA;ICGC;COSMIC	9.540	Up-regulation
Atypical_PIKK_ATM_ATM_ST	Q5UIP0	RIF1	Q13315	ATM	S1454	L1451I	1451	Missense	distal	-3	no	11.088	11.549	EPSD	TCGA;ICGC;COSMIC	9.540	Up-regulation
Atypical_PIKK_ATM_ATM_ST	Q5UIP0	RIF1	Q13315	ATM	S1454	D1460Y	1460	Missense	distal	6	no	11.088	11.069	EPSD	TCGA;ICGC;COSMIC	9.540	Down-regulation
Atypical_PIKK_ATM_ATM_ST	Q5UIP0	RIF1	Q13315	ATM	S1454	P1450H	1450	Missense	distal	-4	no	11.088	11.078	EPSD	TCGA;ICGC	9.540	Down-regulation
Atypical_PIKK_ATM_ATM_ST	Q5UIP0	RIF1	Q13315	ATM	S1454	K1459T	1459	Missense	distal	5	no	11.088	11.067	EPSD	TCGA;ICGC;COSMIC	9.540	Down-regulation
Atypical_PIKK_ATM_ATM_ST	Q5UIP0	RIF1	Q13315	ATM	T1518	D1523H	1523	Missense	distal	5	no	14.892	14.945	EPSD	TCGA;ICGC;COSMIC	9.540	Up-regulation
Atypical_PIKK_ATM_ATM_ST	Q5UIP0	RIF1	Q13315	ATM	T1518	D1520G	1520	Missense	proximal	2	no	14.892	13.653	EPSD	TCGA;ICGC	9.540	Down-regulation
Atypical_PIKK_ATM_ATM_ST	Q5UIP0	RIF1	Q13315	ATM	S1542	R1535W	1535	Missense	distal	-7	no	13.468	13.278	EPSD	TCGA;ICGC;COSMIC	9.540	Down-regulation
Atypical_PIKK_ATM_ATM_ST	Q5UIP0	RIF1	Q13315	ATM	S1542	S1542Y	1542	Missense	central	0	yes	13.468	0.000	EPSD	TCGA	9.540	Loss
Atypical_PIKK_ATM_ATM_ST	Q5UIP0	RIF1	Q13315	ATM	S1554	S1557L	1557	Missense	distal	3	no	9.723	10.005	EPSD	TCGA;ICGC;COSMIC	9.540	Up-regulation
Atypical_PIKK_ATM_ATM_ST	Q5UIP0	RIF1	Q13315	ATM	S1556	S1557L	1557	Missense	proximal	1	no	4.265	9.686	EPSD	TCGA;ICGC;COSMIC	9.540	Gain
Atypical_PIKK_ATM_ATM_ST	Q5UIP0	RIF1	Q13315	ATM	S1707	T1712A	1712	Missense	distal	5	no	9.647	9.711	EPSD	TCGA;ICGC;COSMIC	9.540	Up-regulation
Atypical_PIKK_ATM_ATM_ST	Q5UIP0	RIF1	Q13315	ATM	S1707	E1710K	1710	Missense	distal	3	no	9.647	9.936	EPSD	TCGA;ICGC;COSMIC	9.540	Up-regulation
Atypical_PIKK_ATM_ATM_ST	Q5UIP0	RIF1	Q13315	ATM	S1709	T1712A	1712	Missense	distal	3	no	9.587	9.562	EPSD	TCGA;ICGC;COSMIC	9.540	Down-regulation
Atypical_PIKK_ATM_ATM_ST	Q5UIP0	RIF1	Q13315	ATM	S1709	E1710K	1710	Missense	proximal	1	no	9.587	8.635	EPSD	TCGA;ICGC;COSMIC	9.540	Loss
Atypical_PIKK_ATM_ATM_ST	Q5UIP0	RIF1	Q13315	ATM	S1772	A1769T	1769	Missense	distal	-3	no	9.763	10.140	EPSD	TCGA;ICGC;COSMIC	9.540	Up-regulation
Atypical_PIKK_ATM_ATM_ST	Q5UIP0	RIF1	Q13315	ATM	S1772	S1777Y	1777	Missense	distal	5	no	9.763	9.827	EPSD	TCGA;ICGC	9.540	Up-regulation
Atypical_PIKK_ATM_ATM_ST	Q5UIP0	RIF1	Q13315	ATM	S1774	A1769T	1769	Missense	distal	-5	no	9.863	9.782	EPSD	TCGA;ICGC;COSMIC	9.540	Down-regulation
Atypical_PIKK_ATM_ATM_ST	Q5UIP0	RIF1	Q13315	ATM	S1774	S1777Y	1777	Missense	distal	3	no	9.863	10.105	EPSD	TCGA;ICGC	9.540	Up-regulation
Atypical_PIKK_ATM_ATM_ST	Q5UIP0	RIF1	Q13315	ATM	T1776	S1777Y	1777	Missense	proximal	1	no	4.119	10.181	EPSD	TCGA;ICGC	9.540	Gain
Atypical_PIKK_ATM_ATM_ST	Q5UIP0	RIF1	Q13315	ATM	S1777	S1777Y	1777	Missense	central	0	yes	14.969	0.000	EPSD	TCGA;ICGC	9.540	Loss
Atypical_PIKK_ATM_ATM_ST	Q5UIP0	RIF1	Q13315	ATM	S1826	K1819R	1819	Missense	distal	-7	no	9.782	9.696	EPSD	TCGA;ICGC;COSMIC	9.540	Down-regulation
Atypical_PIKK_ATM_ATM_ST	Q5UIP0	RIF1	Q13315	ATM	S1826	S1826Y	1826	Missense	central	0	yes	9.782	0.000	EPSD	TCGA;ICGC	9.540	Loss
Atypical_PIKK_ATM_ATM_ST	Q5UIP0	RIF1	Q13315	ATM	S1826	V1832A	1832	Missense	distal	6	no	9.782	9.813	EPSD	TCGA;ICGC;COSMIC	9.540	Up-regulation
Atypical_PIKK_ATM_ATM_ST	Q5UIP0	RIF1	Q13315	ATM	S1848	E1853D	1853	Missense	distal	5	no	10.557	10.815	EPSD	TCGA;ICGC;COSMIC	9.540	Up-regulation
Atypical_PIKK_ATM_ATM_ST	Q5UIP0	RIF1	Q13315	ATM	S1851	E1853D	1853	Missense	proximal	2	no	14.608	14.477	PhosphoSitePlus	TCGA;ICGC;COSMIC	9.540	Down-regulation
Atypical_PIKK_ATM_ATM_ST	Q5UIP0	RIF1	Q13315	ATM	S1854	E1853D	1853	Missense	proximal	-1	no	11.330	11.066	EPSD	TCGA;ICGC;COSMIC	9.540	Down-regulation
Atypical_PIKK_ATM_ATM_ST	Q5UIP0	RIF1	Q13315	ATM	S1873	G1867R	1867	Missense	distal	-6	no	13.126	13.147	EPSD	TCGA	9.540	Up-regulation
Atypical_PIKK_ATM_ATM_ST	Q5UIP0	RIF1	Q13315	ATM	S1873	G1867E	1867	Missense	distal	-6	no	13.126	13.515	EPSD	TCGA;ICGC;COSMIC	9.540	Up-regulation
Atypical_PIKK_ATM_ATM_ST	Q5UIP0	RIF1	Q13315	ATM	S2011	T2014M	2014	Missense	distal	3	no	9.802	9.977	EPSD	TCGA;ICGC	9.540	Up-regulation
Atypical_PIKK_ATM_ATM_ST	Q5UIP0	RIF1	Q13315	ATM	S2124	S2129C	2129	Missense	distal	5	no	14.155	14.381	EPSD	TCGA;ICGC;COSMIC	9.540	Up-regulation
Atypical_PIKK_ATM_ATM_ST	Q5UIP0	RIF1	Q13315	ATM	S2129	S2129C	2129	Missense	central	0	yes	11.021	0.000	EPSD	TCGA;ICGC;COSMIC	9.540	Loss
Atypical_PIKK_ATM_ATM_ST	Q5UIP0	RIF1	Q13315	ATM	S2161	L2155F	2155	Missense	distal	-6	no	10.642	10.399	EPSD	TCGA;ICGC;COSMIC	9.540	Down-regulation
Atypical_PIKK_ATM_ATM_ST	Q5UIP0	RIF1	Q13315	ATM	S2161	S2157P	2157	Missense	distal	-4	no	10.642	9.973	EPSD	TCGA;ICGC;COSMIC	9.540	Down-regulation
Atypical_PIKK_ATM_ATM_ST	Q5UIP0	RIF1	Q13315	ATM	S2161	R2168C	2168	Missense	distal	7	no	10.642	10.659	EPSD	TCGA;ICGC	9.540	Up-regulation
Atypical_PIKK_ATM_ATM_ST	Q5UIP0	RIF1	Q13315	ATM	S2161	Q2166R	2166	Missense	distal	5	no	10.642	10.754	EPSD	TCGA;ICGC;COSMIC	9.540	Up-regulation
Atypical_PIKK_ATM_ATM_ST	Q5UIP0	RIF1	Q13315	ATM	S2161	R2168H	2168	Missense	distal	7	no	10.642	10.636	EPSD	TCGA;ICGC;COSMIC;GDSC;CCLE	9.540	Down-regulation
Atypical_PIKK_ATM_ATM_ST	Q5UIP0	RIF1	Q13315	ATM	S2176	S2172F	2172	Missense	distal	-4	no	9.979	8.580	EPSD	TCGA;ICGC;COSMIC	9.540	Loss
Atypical_PIKK_ATM_ATM_ST	Q5UIP0	RIF1	Q13315	ATM	S2176	A2175T	2175	Missense	proximal	-1	no	9.979	10.150	EPSD	TCGA;ICGC;COSMIC	9.540	Up-regulation
Atypical_PIKK_ATM_ATM_ST	Q5UIP0	RIF1	Q13315	ATM	S2196	R2203C	2203	Missense	distal	7	no	10.128	10.146	EPSD	TCGA;ICGC;COSMIC	9.540	Up-regulation
Atypical_PIKK_ATM_ATM_ST	Q5UIP0	RIF1	Q13315	ATM	S2196	R2202C	2202	Missense	distal	6	no	10.128	10.074	EPSD	TCGA;ICGC;COSMIC	9.540	Down-regulation
Atypical_PIKK_ATM_ATM_ST	Q5UIP0	RIF1	Q13315	ATM	S2196	R2203H	2203	Missense	distal	7	no	10.128	10.122	EPSD	TCGA;ICGC	9.540	Down-regulation
Atypical_PIKK_ATM_ATM_ST	Q5UIP0	RIF1	Q13315	ATM	S2243	V2240I	2240	Missense	distal	-3	no	10.397	10.648	EPSD	TCGA;ICGC;COSMIC	9.540	Up-regulation
Atypical_PIKK_ATM_ATM_ST	Q5UIP0	RIF1	Q13315	ATM	T2246	N2251S	2251	Missense	distal	5	no	14.199	14.225	EPSD	TCGA;ICGC;COSMIC	9.540	Up-regulation
Atypical_PIKK_ATM_ATM_ST	Q5UIP0	RIF1	Q13315	ATM	T2246	V2240I	2240	Missense	distal	-6	no	14.199	14.055	EPSD	TCGA;ICGC;COSMIC	9.540	Down-regulation
Atypical_PIKK_ATM_ATM_ST	Q5UIP0	RIF1	Q13315	ATM	S2260	R2264H	2264	Missense	distal	4	no	10.283	10.219	EPSD	TCGA;ICGC	9.540	Down-regulation
Atypical_PIKK_ATM_ATM_ST	Q5UIP0	RIF1	Q13315	ATM	S2401	L2399P	2399	Missense	proximal	-2	no	9.398	9.551	EPSD	TCGA;COSMIC	9.540	Gain
Atypical_PIKK_ATM_ATM_ST	Q5UIP0	RIF1	Q13315	ATM	S2465	L2459I	2459	Missense	distal	-6	no	13.660	13.548	EPSD	TCGA;COSMIC	9.540	Down-regulation
Atypical_PIKK_ATM_ATM_ST	Q13541	EIF4EBP1	Q13315	ATM	S101	A107V	107	Missense	distal	6	no	12.020	11.989	EPSD	TCGA;ICGC;COSMIC;GDSC;CCLE	9.540	Down-regulation
Atypical_PIKK_ATM_ATM_ST	Q13541	EIF4EBP1	Q13315	ATM	S112	G109S	109	Missense	distal	-3	no	15.382	15.104	EPSD	TCGA	9.540	Down-regulation
Atypical_PIKK_ATM_ATM_ST	Q13541	EIF4EBP1	Q13315	ATM	S112	G109C	109	Missense	distal	-3	no	15.382	15.272	EPSD	TCGA;COSMIC	9.540	Down-regulation
Atypical_PIKK_ATM_ATM_ST	Q13541	EIF4EBP1	Q13315	ATM	S112	A107V	107	Missense	distal	-5	no	15.382	15.503	EPSD	TCGA;ICGC;COSMIC;GDSC;CCLE	9.540	Up-regulation
Atypical_PIKK_ATM_ATM_ST	O15164	TRIM24	Q13315	ATM	T120	R126C	126	Missense	distal	6	no	12.553	12.498	EPSD	TCGA;ICGC;COSMIC	9.540	Down-regulation
Atypical_PIKK_ATM_ATM_ST	O15164	TRIM24	Q13315	ATM	T120	S116T	116	Missense	distal	-4	no	12.553	12.170	EPSD	TCGA;ICGC;COSMIC	9.540	Down-regulation
Atypical_PIKK_ATM_ATM_ST	O15164	TRIM24	Q13315	ATM	T120	R126S	126	Missense	distal	6	no	12.553	12.571	EPSD	TCGA;ICGC;COSMIC	9.540	Up-regulation
Atypical_PIKK_ATM_ATM_ST	O15164	TRIM24	Q13315	ATM	S209	G214V	214	Missense	distal	5	no	11.788	11.822	EPSD	TCGA;ICGC;COSMIC	9.540	Up-regulation
Atypical_PIKK_ATM_ATM_ST	O15164	TRIM24	Q13315	ATM	S209	P210L	210	Missense	proximal	1	no	11.788	10.233	EPSD	TCGA;ICGC;COSMIC	9.540	Down-regulation
Atypical_PIKK_ATM_ATM_ST	O15164	TRIM24	Q13315	ATM	S209	K205Q	205	Missense	distal	-4	no	11.788	12.037	EPSD	TCGA;ICGC	9.540	Up-regulation
Atypical_PIKK_ATM_ATM_ST	O15164	TRIM24	Q13315	ATM	S217	G214V	214	Missense	distal	-3	no	14.219	14.359	EPSD	TCGA;ICGC;COSMIC	9.540	Up-regulation
Atypical_PIKK_ATM_ATM_ST	O15164	TRIM24	Q13315	ATM	S217	P210L	210	Missense	distal	-7	no	14.219	13.867	EPSD	TCGA;ICGC;COSMIC	9.540	Down-regulation
Atypical_PIKK_ATM_ATM_ST	O15164	TRIM24	Q13315	ATM	S445	P447S	447	Missense	proximal	2	no	14.715	15.170	EPSD	TCGA;ICGC;COSMIC	9.540	Up-regulation
Atypical_PIKK_ATM_ATM_ST	O15164	TRIM24	Q13315	ATM	S445	P439S	439	Missense	distal	-6	no	14.715	14.774	EPSD	TCGA;ICGC;COSMIC	9.540	Up-regulation
Atypical_PIKK_ATM_ATM_ST	O15164	TRIM24	Q13315	ATM	S445	P439H	439	Missense	distal	-6	no	14.715	14.595	EPSD	TCGA;ICGC	9.540	Down-regulation
Atypical_PIKK_ATM_ATM_ST	O15164	TRIM24	Q13315	ATM	T461	P460S	460	Missense	proximal	-1	no	12.153	12.445	EPSD	TCGA;ICGC;COSMIC	9.540	Up-regulation
Atypical_PIKK_ATM_ATM_ST	O15164	TRIM24	Q13315	ATM	S590	S585F	585	Missense	distal	-5	no	11.025	11.348	EPSD	TCGA;COSMIC	9.540	Up-regulation
Atypical_PIKK_ATM_ATM_ST	O15164	TRIM24	Q13315	ATM	S590	T592M	592	Missense	proximal	2	no	11.025	10.230	EPSD	TCGA;COSMIC;GDSC;CCLE	9.540	Down-regulation
Atypical_PIKK_ATM_ATM_ST	O15164	TRIM24	Q13315	ATM	S685	R684C	684	Missense	proximal	-1	no	9.650	9.825	EPSD	TCGA;COSMIC	9.540	Up-regulation
Atypical_PIKK_ATM_ATM_ST	O15164	TRIM24	Q13315	ATM	S701	G695E	695	Missense	distal	-6	no	10.813	11.202	EPSD	TCGA;COSMIC	9.540	Up-regulation
Atypical_PIKK_ATM_ATM_ST	O15164	TRIM24	Q13315	ATM	S744	S748F	748	Missense	distal	4	no	9.422	10.250	EPSD	TCGA;COSMIC	9.540	Gain
Atypical_PIKK_ATM_ATM_ST	O15164	TRIM24	Q13315	ATM	S762	S762F	762	Missense	central	0	yes	10.008	0.000	EPSD	TCGA;COSMIC	9.540	Loss
Atypical_PIKK_ATM_ATM_ST	O15164	TRIM24	Q13315	ATM	S768	S771C	771	Missense	distal	3	no	14.556	14.977	PhosphoSitePlus	TCGA;COSMIC	9.540	Up-regulation
Atypical_PIKK_ATM_ATM_ST	O15164	TRIM24	Q13315	ATM	S768	S771F	771	Missense	distal	3	no	14.556	15.138	PhosphoSitePlus	TCGA;COSMIC	9.540	Up-regulation
Atypical_PIKK_ATM_ATM_ST	O15164	TRIM24	Q13315	ATM	S768	S762F	762	Missense	distal	-6	no	14.556	14.025	PhosphoSitePlus	TCGA;COSMIC	9.540	Down-regulation
Atypical_PIKK_ATM_ATM_ST	O15164	TRIM24	Q13315	ATM	S808	D806Y	806	Missense	proximal	-2	no	13.483	13.612	EPSD	TCGA;COSMIC	9.540	Up-regulation
Atypical_PIKK_ATM_ATM_ST	O15164	TRIM24	Q13315	ATM	S811	D806Y	806	Missense	distal	-5	no	10.048	10.283	EPSD	TCGA;COSMIC	9.540	Up-regulation
Atypical_PIKK_ATM_ATM_ST	O15164	TRIM24	Q13315	ATM	S1025	D1031N	1031	Missense	distal	6	no	11.093	11.105	EPSD	TCGA;COSMIC	9.540	Up-regulation
Atypical_PIKK_ATM_ATM_ST	Q92630	DYRK2	Q13315	ATM	S442	D447G	447	Missense	distal	5	no	13.362	13.454	EPSD;PhosphoSitePlus	TCGA;ICGC	9.540	Up-regulation
Atypical_PIKK_ATM_ATM_ST	Q9NY61	AATF	Q13315	ATM	S99	S94F	94	Missense	distal	-5	no	9.313	9.636	EPSD	TCGA;ICGC	9.540	Gain
Atypical_PIKK_ATM_ATM_ST	Q9NY61	AATF	Q13315	ATM	S104	D100G	100	Missense	distal	-4	no	10.401	9.617	EPSD	TCGA;ICGC	9.540	Down-regulation
Atypical_PIKK_ATM_ATM_ST	Q9NY61	AATF	Q13315	ATM	S104	E97D	97	Missense	distal	-7	no	10.401	9.823	EPSD	TCGA;ICGC	9.540	Down-regulation
Atypical_PIKK_ATM_ATM_ST	Q9NY61	AATF	Q13315	ATM	S104	E101K	101	Missense	distal	-3	no	10.401	10.468	EPSD	TCGA;ICGC	9.540	Up-regulation
Atypical_PIKK_ATM_ATM_ST	Q9NY61	AATF	Q13315	ATM	S109	G113C	113	Missense	distal	4	no	9.710	10.091	EPSD	TCGA;ICGC	9.540	Up-regulation
Atypical_PIKK_ATM_ATM_ST	Q9NY61	AATF	Q13315	ATM	S109	E116G	116	Missense	distal	7	no	9.710	9.756	EPSD	TCGA;ICGC	9.540	Up-regulation
Atypical_PIKK_ATM_ATM_ST	Q9NY61	AATF	Q13315	ATM	S143	P147S	147	Missense	distal	4	no	9.847	9.724	EPSD	TCGA;ICGC	9.540	Down-regulation
Atypical_PIKK_ATM_ATM_ST	Q9NY61	AATF	Q13315	ATM	S143	F149S	149	Missense	distal	6	no	9.847	9.923	EPSD	TCGA;ICGC	9.540	Up-regulation
Atypical_PIKK_ATM_ATM_ST	Q9NY61	AATF	Q13315	ATM	S189	S193N	193	Missense	distal	4	no	15.955	16.082	PhosphoSitePlus	TCGA;ICGC	9.540	Up-regulation
Atypical_PIKK_ATM_ATM_ST	Q9NY61	AATF	Q13315	ATM	S203	D206Y	206	Missense	distal	3	no	10.110	10.168	EPSD	TCGA;ICGC	9.540	Up-regulation
Atypical_PIKK_ATM_ATM_ST	Q9NY61	AATF	Q13315	ATM	S316	A314V	314	Missense	proximal	-2	no	10.239	9.762	EPSD	TCGA;ICGC;GDSC	9.540	Down-regulation
Atypical_PIKK_ATM_ATM_ST	Q9NY61	AATF	Q13315	ATM	T394	D397N	397	Missense	distal	3	no	11.983	12.000	EPSD	TCGA;ICGC	9.540	Up-regulation
Atypical_PIKK_ATM_ATM_ST	Q9NY61	AATF	Q13315	ATM	T394	M401I	401	Missense	distal	7	no	11.983	11.981	EPSD	TCGA;ICGC	9.540	Down-regulation
Atypical_PIKK_ATM_ATM_ST	Q9NY61	AATF	Q13315	ATM	T410	R405S	405	Missense	distal	-5	no	11.972	11.896	EPSD	TCGA;ICGC	9.540	Down-regulation
Atypical_PIKK_ATM_ATM_ST	Q9NY61	AATF	Q13315	ATM	T410	R414H	414	Missense	distal	4	no	11.972	11.908	EPSD	TCGA;ICGC	9.540	Down-regulation
Atypical_PIKK_ATM_ATM_ST	Q9NY61	AATF	Q13315	ATM	T410	R408Q	408	Missense	proximal	-2	no	11.972	12.291	EPSD	TCGA;ICGC	9.540	Up-regulation
Atypical_PIKK_ATM_ATM_ST	Q9NY61	AATF	Q13315	ATM	S478	S478F	478	Missense	central	0	yes	10.199	0.000	EPSD	TCGA;ICGC	9.540	Loss
Atypical_PIKK_ATM_ATM_ST	Q9NY61	AATF	Q13315	ATM	S478	I472M	472	Missense	distal	-6	no	10.199	10.355	EPSD	TCGA;ICGC	9.540	Up-regulation
Atypical_PIKK_ATM_ATM_ST	Q9NY61	AATF	Q13315	ATM	S478	R474W	474	Missense	distal	-4	no	10.199	9.723	EPSD	TCGA;ICGC	9.540	Down-regulation
Atypical_PIKK_ATM_ATM_ST	P51532	SMARCA4	Q13315	ATM	S610	E604K	604	Missense	distal	-6	no	13.887	13.586	EPSD	TCGA;ICGC;COSMIC	9.540	Down-regulation
Atypical_PIKK_ATM_ATM_ST	P51532	SMARCA4	Q13315	ATM	S610	G603V	603	Missense	distal	-7	no	13.887	13.919	EPSD	TCGA;ICGC	9.540	Up-regulation
Atypical_PIKK_ATM_ATM_ST	P51532	SMARCA4	Q13315	ATM	S662	E669K	669	Missense	distal	7	no	9.942	9.969	EPSD	TCGA;ICGC;COSMIC	9.540	Up-regulation
Atypical_PIKK_ATM_ATM_ST	P51532	SMARCA4	Q13315	ATM	S662	E665D	665	Missense	distal	3	no	9.942	10.302	EPSD	TCGA	9.540	Up-regulation
Atypical_PIKK_ATM_ATM_ST	P51532	SMARCA4	Q13315	ATM	S721	Q722H	722	Missense	proximal	1	no	15.380	0.471	PhosphoSitePlus	TCGA;ICGC;COSMIC	9.540	Loss
Atypical_PIKK_ATM_ATM_ST	P51532	SMARCA4	Q13315	ATM	S721	D715N	715	Missense	distal	-6	no	15.380	15.291	PhosphoSitePlus	TCGA;ICGC;COSMIC	9.540	Down-regulation
Atypical_PIKK_ATM_ATM_ST	P51532	SMARCA4	Q13315	ATM	S837	R841S	841	Missense	distal	4	no	12.345	12.164	EPSD	TCGA;ICGC;COSMIC	9.540	Down-regulation
Atypical_PIKK_ATM_ATM_ST	P51532	SMARCA4	Q13315	ATM	T859	E861K	861	Missense	proximal	2	no	10.761	9.430	EPSD	TCGA;ICGC;COSMIC;GDSC;CCLE	9.540	Loss
Atypical_PIKK_ATM_ATM_ST	P51532	SMARCA4	Q13315	ATM	T859	T859M	859	Missense	central	0	yes	10.761	0.000	EPSD	TCGA;ICGC;COSMIC	9.540	Loss
Atypical_PIKK_ATM_ATM_ST	P51532	SMARCA4	Q13315	ATM	S1380	L1383P	1383	Missense	distal	3	no	9.956	9.826	EPSD	TCGA	9.540	Down-regulation
Atypical_PIKK_ATM_ATM_ST	P51532	SMARCA4	Q13315	ATM	S1380	K1386N	1386	Missense	distal	6	no	9.956	9.967	EPSD	TCGA;ICGC;COSMIC	9.540	Up-regulation
Atypical_PIKK_ATM_ATM_ST	P51532	SMARCA4	Q13315	ATM	S1382	L1383P	1383	Missense	proximal	1	no	9.359	10.913	EPSD	TCGA	9.540	Gain
Atypical_PIKK_ATM_ATM_ST	P51532	SMARCA4	Q13315	ATM	S1452	R1445W	1445	Missense	distal	-7	no	9.638	9.448	EPSD	TCGA;COSMIC;CCLE	9.540	Loss
Atypical_PIKK_ATM_ATM_ST	P51532	SMARCA4	Q13315	ATM	S1452	A1448T	1448	Missense	distal	-4	no	9.638	9.765	EPSD	TCGA;ICGC;COSMIC	9.540	Up-regulation
Atypical_PIKK_ATM_ATM_ST	P51532	SMARCA4	Q13315	ATM	S1452	P1455S	1455	Missense	distal	3	no	9.638	9.486	EPSD	TCGA;COSMIC;CCLE	9.540	Loss
Atypical_PIKK_ATM_ATM_ST	P51532	SMARCA4	Q13315	ATM	S1586	R1591W	1591	Missense	distal	5	no	11.512	11.536	EPSD	TCGA	9.540	Up-regulation
Atypical_PIKK_ATM_ATM_ST	P51532	SMARCA4	Q13315	ATM	S1586	S1588F	1588	Missense	proximal	2	no	11.512	10.034	EPSD	TCGA;COSMIC	9.540	Down-regulation
Atypical_PIKK_ATM_ATM_ST	P51532	SMARCA4	Q13315	ATM	S1586	E1582K	1582	Missense	distal	-4	no	11.512	10.540	EPSD	TCGA;COSMIC	9.540	Down-regulation
Atypical_PIKK_ATM_ATM_ST	P51532	SMARCA4	Q13315	ATM	S1588	R1591W	1591	Missense	distal	3	no	9.494	9.686	EPSD	TCGA	9.540	Gain
Atypical_PIKK_ATM_ATM_ST	P51532	SMARCA4	Q13315	ATM	S1590	R1591W	1591	Missense	proximal	1	no	11.268	5.314	EPSD	TCGA	9.540	Loss
Atypical_PIKK_ATM_ATM_ST	P51532	SMARCA4	Q13315	ATM	S1590	S1588F	1588	Missense	proximal	-2	no	11.268	10.368	EPSD	TCGA;COSMIC	9.540	Down-regulation
Atypical_PIKK_ATM_ATM_ST	Q03111	MLLT1	Q13315	ATM	S209	R206H	206	Missense	distal	-3	no	9.721	9.075	EPSD	TCGA;ICGC;COSMIC;GDSC;CCLE	9.540	Loss
Atypical_PIKK_ATM_ATM_ST	Q03111	MLLT1	Q13315	ATM	S209	R206L	206	Missense	distal	-3	no	9.721	9.190	EPSD	TCGA;ICGC;COSMIC	9.540	Loss
Atypical_PIKK_ATM_ATM_ST	Q03111	MLLT1	Q13315	ATM	S361	S366F	366	Missense	distal	5	no	9.882	10.188	EPSD	TCGA;ICGC;COSMIC	9.540	Up-regulation
Atypical_PIKK_ATM_ATM_ST	Q03111	MLLT1	Q13315	ATM	S361	E358D	358	Missense	distal	-3	no	9.882	10.287	EPSD	TCGA;ICGC	9.540	Up-regulation
Atypical_PIKK_ATM_ATM_ST	Q03111	MLLT1	Q13315	ATM	S361	V356L	356	Missense	distal	-5	no	9.882	9.791	EPSD	TCGA;ICGC;COSMIC	9.540	Down-regulation
Atypical_PIKK_ATM_ATM_ST	Q03111	MLLT1	Q13315	ATM	S375	S371Y	371	Missense	distal	-4	no	10.488	9.387	EPSD	TCGA;ICGC	9.540	Loss
Atypical_PIKK_ATM_ATM_ST	Q03111	MLLT1	Q13315	ATM	S382	S383L	383	Missense	proximal	1	no	4.469	9.889	EPSD	TCGA;ICGC;COSMIC	9.540	Gain
Atypical_PIKK_ATM_ATM_ST	Q03111	MLLT1	Q13315	ATM	S387	S383L	383	Missense	distal	-4	no	11.725	10.786	EPSD	TCGA;ICGC;COSMIC	9.540	Down-regulation
Atypical_PIKK_ATM_ATM_ST	Q03111	MLLT1	Q13315	ATM	S387	P393S	393	Missense	distal	6	no	11.725	11.736	EPSD	TCGA;ICGC;COSMIC	9.540	Up-regulation
Atypical_PIKK_ATM_ATM_ST	Q03111	MLLT1	Q13315	ATM	S394	Q395E	395	Missense	proximal	1	no	17.632	11.736	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	9.540	Down-regulation
Atypical_PIKK_ATM_ATM_ST	Q03111	MLLT1	Q13315	ATM	S394	P393S	393	Missense	proximal	-1	no	17.632	17.924	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	9.540	Up-regulation
Atypical_PIKK_ATM_ATM_ST	Q03111	MLLT1	Q13315	ATM	S398	Q395E	395	Missense	distal	-3	no	15.392	15.268	PhosphoSitePlus;EPSD	TCGA;ICGC;COSMIC	9.540	Down-regulation
Atypical_PIKK_ATM_ATM_ST	Q03111	MLLT1	Q13315	ATM	S398	P393S	393	Missense	distal	-5	no	15.392	15.388	PhosphoSitePlus;EPSD	TCGA;ICGC;COSMIC	9.540	Down-regulation
Atypical_PIKK_ATM_ATM_ST	Q03111	MLLT1	Q13315	ATM	S421	A425V	425	Missense	distal	4	no	10.097	10.749	EPSD	TCGA;ICGC;COSMIC	9.540	Up-regulation
Atypical_PIKK_ATM_ATM_ST	Q03111	MLLT1	Q13315	ATM	S454	S451F	451	Missense	distal	-3	no	10.404	11.476	EPSD	TCGA;ICGC;COSMIC	9.540	Up-regulation
Atypical_PIKK_ATM_ATM_ST	Q03111	MLLT1	Q13315	ATM	S475	E477K	477	Missense	proximal	2	no	12.248	10.918	EPSD	TCGA;ICGC;COSMIC	9.540	Down-regulation
Atypical_PIKK_ATM_ATM_ST	Q8IZL8	PELP1	Q13315	ATM	S251	E258K	258	Missense	distal	7	no	12.382	12.408	EPSD	TCGA;ICGC;COSMIC	9.540	Up-regulation
Atypical_PIKK_ATM_ATM_ST	Q8IZL8	PELP1	Q13315	ATM	S481	G484W	484	Missense	distal	3	no	9.663	9.910	EPSD	TCGA;COSMIC	9.540	Up-regulation
Atypical_PIKK_ATM_ATM_ST	Q8IZL8	PELP1	Q13315	ATM	S481	G480E	480	Missense	proximal	-1	no	9.663	10.065	EPSD	TCGA;COSMIC	9.540	Up-regulation
Atypical_PIKK_ATM_ATM_ST	Q8IZL8	PELP1	Q13315	ATM	S481	G480R	480	Missense	proximal	-1	no	9.663	9.480	EPSD	TCGA;COSMIC	9.540	Loss
Atypical_PIKK_ATM_ATM_ST	Q8IZL8	PELP1	Q13315	ATM	S481	P478S	478	Missense	distal	-3	no	9.663	9.466	EPSD	TCGA;COSMIC	9.540	Loss
Atypical_PIKK_ATM_ATM_ST	Q8IZL8	PELP1	Q13315	ATM	S1033	E1038D	1038	Missense	distal	5	no	13.675	13.932	PhosphoSitePlus	TCGA;COSMIC	9.540	Up-regulation
Atypical_PIKK_ATM_ATM_ST	Q8IZL8	PELP1	Q13315	ATM	S1033	L1026M	1026	Missense	distal	-7	no	13.675	13.787	PhosphoSitePlus	TCGA	9.540	Up-regulation
Atypical_PIKK_ATM_ATM_ST	Q8IZL8	PELP1	Q13315	ATM	T1069	E1070Q	1070	Missense	proximal	1	no	6.061	11.958	EPSD	TCGA;COSMIC	9.540	Gain
Atypical_PIKK_ATM_ATM_ST	O14757	CHEK1	Q13315	ATM	S284	G289V	289	Missense	distal	5	no	9.615	9.649	EPSD	TCGA;ICGC;COSMIC	9.540	Up-regulation
Atypical_PIKK_ATM_ATM_ST	O14757	CHEK1	Q13315	ATM	S284	G281D	281	Missense	distal	-3	no	9.615	9.582	EPSD	TCGA;ICGC;COSMIC	9.540	Down-regulation
Atypical_PIKK_ATM_ATM_ST	O14757	CHEK1	Q13315	ATM	S284	T279I	279	Missense	distal	-5	no	9.615	9.818	EPSD	TCGA;ICGC;COSMIC	9.540	Up-regulation
Atypical_PIKK_ATM_ATM_ST	O14757	CHEK1	Q13315	ATM	S284	S284L	284	Missense	central	0	yes	9.615	0.000	EPSD	TCGA;ICGC;COSMIC	9.540	Loss
Atypical_PIKK_ATM_ATM_ST	O14757	CHEK1	Q13315	ATM	S284	S288R	288	Missense	distal	4	no	9.615	9.797	EPSD	TCGA;ICGC;COSMIC	9.540	Up-regulation
Atypical_PIKK_ATM_ATM_ST	O14757	CHEK1	Q13315	ATM	S286	G289V	289	Missense	distal	3	no	9.874	10.087	EPSD	TCGA;ICGC;COSMIC	9.540	Up-regulation
Atypical_PIKK_ATM_ATM_ST	O14757	CHEK1	Q13315	ATM	S286	G281D	281	Missense	distal	-5	no	9.874	9.608	EPSD	TCGA;ICGC;COSMIC	9.540	Down-regulation
Atypical_PIKK_ATM_ATM_ST	O14757	CHEK1	Q13315	ATM	S286	T279I	279	Missense	distal	-7	no	9.874	9.291	EPSD	TCGA;ICGC;COSMIC	9.540	Loss
Atypical_PIKK_ATM_ATM_ST	O14757	CHEK1	Q13315	ATM	S286	S284L	284	Missense	proximal	-2	no	9.874	9.484	EPSD	TCGA;ICGC;COSMIC	9.540	Loss
Atypical_PIKK_ATM_ATM_ST	O14757	CHEK1	Q13315	ATM	S286	S288R	288	Missense	proximal	2	no	9.874	8.876	EPSD	TCGA;ICGC;COSMIC	9.540	Loss
Atypical_PIKK_ATM_ATM_ST	O14757	CHEK1	Q13315	ATM	S317	R322H	322	Missense	distal	5	no	16.627	16.601	EPSD	TCGA;ICGC;COSMIC	9.540	Down-regulation
Atypical_PIKK_ATM_ATM_ST	O14757	CHEK1	Q13315	ATM	S317	G324C	324	Missense	distal	7	no	16.627	16.638	EPSD	TCGA;ICGC;COSMIC	9.540	Up-regulation
Atypical_PIKK_ATM_ATM_ST	O14757	CHEK1	Q13315	ATM	S331	G324C	324	Missense	distal	-7	no	11.029	10.868	EPSD	TCGA;ICGC;COSMIC	9.540	Down-regulation
Atypical_PIKK_ATM_ATM_ST	O14757	CHEK1	Q13315	ATM	S331	D336N	336	Missense	distal	5	no	11.029	10.917	EPSD	TCGA;ICGC;COSMIC	9.540	Down-regulation
Atypical_PIKK_ATM_ATM_ST	O14757	CHEK1	Q13315	ATM	S331	K337R	337	Missense	distal	6	no	11.029	11.032	EPSD	TCGA;ICGC;COSMIC	9.540	Up-regulation
Atypical_PIKK_ATM_ATM_ST	O14757	CHEK1	Q13315	ATM	S333	D336N	336	Missense	distal	3	no	11.340	11.357	EPSD	TCGA;ICGC;COSMIC	9.540	Up-regulation
Atypical_PIKK_ATM_ATM_ST	O14757	CHEK1	Q13315	ATM	S333	V339I	339	Missense	distal	6	no	11.340	11.324	EPSD	TCGA;ICGC;COSMIC	9.540	Down-regulation
Atypical_PIKK_ATM_ATM_ST	O14757	CHEK1	Q13315	ATM	S333	K337R	337	Missense	distal	4	no	11.340	11.443	EPSD	TCGA;ICGC;COSMIC	9.540	Up-regulation
Atypical_PIKK_ATM_ATM_ST	O14757	CHEK1	Q13315	ATM	S345	V339I	339	Missense	distal	-6	no	13.959	13.815	PhosphoSitePlus	TCGA;ICGC;COSMIC	9.540	Down-regulation
Atypical_PIKK_ATM_ATM_ST	O14757	CHEK1	Q13315	ATM	T417	N421H	421	Missense	distal	4	no	10.594	10.585	EPSD	TCGA	9.540	Down-regulation
Atypical_PIKK_ATM_ATM_ST	O14757	CHEK1	Q13315	ATM	T417	R419S	419	Missense	proximal	2	no	10.594	11.592	EPSD	TCGA;ICGC;COSMIC;GDSC;CCLE	9.540	Up-regulation
Atypical_PIKK_ATM_ATM_ST	O14757	CHEK1	Q13315	ATM	T417	S415P	415	Missense	proximal	-2	no	10.594	10.358	EPSD	TCGA;ICGC;COSMIC	9.540	Down-regulation
Atypical_PIKK_ATM_ATM_ST	O14757	CHEK1	Q13315	ATM	S468	D464Y	464	Missense	distal	-4	no	16.723	15.626	EPSD	TCGA;ICGC;COSMIC	9.540	Down-regulation
Atypical_PIKK_ATM_ATM_ST	Q01844	EWSR1	Q13315	ATM	T79	T79I	79	Missense	central	0	yes	11.160	0.000	PhosphoSitePlus	TCGA;ICGC;COSMIC	9.540	Loss
Atypical_PIKK_ATM_ATM_ST	Q16204	CCDC6	Q13315	ATM	S19	S20L	20	Missense	proximal	1	no	4.327	9.748	EPSD	TCGA;ICGC;COSMIC	9.540	Gain
Atypical_PIKK_ATM_ATM_ST	Q16204	CCDC6	Q13315	ATM	S244	P243S	243	Missense	proximal	-1	no	10.292	10.584	EPSD	TCGA;ICGC;COSMIC	9.540	Up-regulation
Atypical_PIKK_ATM_ATM_ST	Q16204	CCDC6	Q13315	ATM	S244	R246K	246	Missense	proximal	2	no	10.292	10.469	EPSD	TCGA;ICGC;COSMIC	9.540	Up-regulation
Atypical_PIKK_ATM_ATM_ST	Q16204	CCDC6	Q13315	ATM	T357	S359F	359	Missense	proximal	2	no	9.839	8.360	EPSD	TCGA;ICGC	9.540	Loss
Atypical_PIKK_ATM_ATM_ST	Q16204	CCDC6	Q13315	ATM	T357	S359Y	359	Missense	proximal	2	no	9.839	8.978	EPSD	TCGA;ICGC;COSMIC	9.540	Loss
Atypical_PIKK_ATM_ATM_ST	Q16204	CCDC6	Q13315	ATM	T357	S351Y	351	Missense	distal	-6	no	9.839	9.589	EPSD	TCGA;ICGC;COSMIC	9.540	Down-regulation
Atypical_PIKK_ATM_ATM_ST	Q16204	CCDC6	Q13315	ATM	T357	P358H	358	Missense	proximal	1	no	9.839	-0.269	EPSD	TCGA;ICGC	9.540	Loss
Atypical_PIKK_ATM_ATM_ST	Q16204	CCDC6	Q13315	ATM	S359	S359F	359	Missense	central	0	yes	10.247	0.000	EPSD	TCGA;ICGC	9.540	Loss
Atypical_PIKK_ATM_ATM_ST	Q16204	CCDC6	Q13315	ATM	S359	S359Y	359	Missense	central	0	yes	10.247	0.000	EPSD	TCGA;ICGC;COSMIC	9.540	Loss
Atypical_PIKK_ATM_ATM_ST	Q16204	CCDC6	Q13315	ATM	S359	P365S	365	Missense	distal	6	no	10.247	10.258	EPSD	TCGA;ICGC;COSMIC	9.540	Up-regulation
Atypical_PIKK_ATM_ATM_ST	Q16204	CCDC6	Q13315	ATM	S359	P358H	358	Missense	proximal	-1	no	10.247	10.335	EPSD	TCGA;ICGC	9.540	Up-regulation
Atypical_PIKK_ATM_ATM_ST	Q16204	CCDC6	Q13315	ATM	S363	S359F	359	Missense	distal	-4	no	11.394	9.995	EPSD	TCGA;ICGC	9.540	Down-regulation
Atypical_PIKK_ATM_ATM_ST	Q16204	CCDC6	Q13315	ATM	S363	S359Y	359	Missense	distal	-4	no	11.394	10.293	EPSD	TCGA;ICGC;COSMIC	9.540	Down-regulation
Atypical_PIKK_ATM_ATM_ST	Q16204	CCDC6	Q13315	ATM	S363	P365S	365	Missense	proximal	2	no	11.394	11.849	EPSD	TCGA;ICGC;COSMIC	9.540	Up-regulation
Atypical_PIKK_ATM_ATM_ST	Q16204	CCDC6	Q13315	ATM	S363	P358H	358	Missense	distal	-5	no	11.394	11.439	EPSD	TCGA;ICGC	9.540	Up-regulation
Atypical_PIKK_ATM_ATM_ST	Q16204	CCDC6	Q13315	ATM	S395	G389E	389	Missense	distal	-6	no	9.210	9.599	EPSD	TCGA;ICGC;COSMIC	9.540	Gain
Atypical_PIKK_ATM_ATM_ST	Q16204	CCDC6	Q13315	ATM	S419	R425W	425	Missense	distal	6	no	13.282	13.250	EPSD	TCGA;ICGC;COSMIC	9.540	Down-regulation
Atypical_PIKK_ATM_ATM_ST	Q16204	CCDC6	Q13315	ATM	S419	F423I	423	Missense	distal	4	no	13.282	13.117	EPSD	TCGA;ICGC;COSMIC	9.540	Down-regulation
Atypical_PIKK_ATM_ATM_ST	Q16204	CCDC6	Q13315	ATM	S419	F423L	423	Missense	distal	4	no	13.282	12.796	EPSD	TCGA;COSMIC	9.540	Down-regulation
Atypical_PIKK_ATM_ATM_ST	Q16204	CCDC6	Q13315	ATM	S419	P412L	412	Missense	distal	-7	no	13.282	12.930	EPSD	TCGA;ICGC;COSMIC	9.540	Down-regulation
Atypical_PIKK_ATM_ATM_ST	Q16204	CCDC6	Q13315	ATM	T434	T427M	427	Missense	distal	-7	no	14.518	14.124	PhosphoSitePlus	TCGA;ICGC;COSMIC	9.540	Down-regulation
Atypical_PIKK_ATM_ATM_ST	Q16204	CCDC6	Q13315	ATM	S459	P454L	454	Missense	distal	-5	no	13.636	13.655	EPSD	TCGA;ICGC;COSMIC	9.540	Up-regulation
Atypical_PIKK_ATM_ATM_ST	Q16204	CCDC6	Q13315	ATM	S459	P454S	454	Missense	distal	-5	no	13.636	13.632	EPSD	TCGA;ICGC;COSMIC	9.540	Down-regulation
Atypical_PIKK_ATM_ATM_ST	Q16204	CCDC6	Q13315	ATM	S459	H466P	466	Missense	distal	7	no	13.636	13.626	EPSD	TCGA;ICGC	9.540	Down-regulation
Atypical_PIKK_ATM_ATM_ST	Q16204	CCDC6	Q13315	ATM	S459	H466Y	466	Missense	distal	7	no	13.636	13.641	EPSD	TCGA;ICGC	9.540	Up-regulation
Atypical_PIKK_ATM_ATM_ST	Q16204	CCDC6	Q13315	ATM	S464	A468V	468	Missense	distal	4	no	14.429	15.082	EPSD	TCGA;ICGC;COSMIC;GDSC;CCLE	9.540	Up-regulation
Atypical_PIKK_ATM_ATM_ST	Q16204	CCDC6	Q13315	ATM	S464	H466P	466	Missense	proximal	2	no	14.429	14.656	EPSD	TCGA;ICGC	9.540	Up-regulation
Atypical_PIKK_ATM_ATM_ST	Q16204	CCDC6	Q13315	ATM	S464	H466Y	466	Missense	proximal	2	no	14.429	14.250	EPSD	TCGA;ICGC	9.540	Down-regulation
Atypical_PIKK_ATM_ATM_ST	Q16204	CCDC6	Q13315	ATM	S472	A468V	468	Missense	distal	-4	no	16.050	15.571	EPSD	TCGA;ICGC;COSMIC;GDSC;CCLE	9.540	Down-regulation
Atypical_PIKK_ATM_ATM_ST	Q16204	CCDC6	Q13315	ATM	S472	H466P	466	Missense	distal	-6	no	16.050	16.170	EPSD	TCGA;ICGC	9.540	Up-regulation
Atypical_PIKK_ATM_ATM_ST	Q16204	CCDC6	Q13315	ATM	S472	H466Y	466	Missense	distal	-6	no	16.050	15.980	EPSD	TCGA;ICGC	9.540	Down-regulation
Atypical_PIKK_ATM_ATM_ST	Q15109	AGER	Q13315	ATM	T195	A197D	197	Missense	proximal	2	no	9.967	10.930	EPSD	TCGA;COSMIC	9.540	Up-regulation
Atypical_PIKK_ATM_ATM_ST	Q15109	AGER	Q13315	ATM	T195	A197T	197	Missense	proximal	2	no	9.967	10.288	EPSD	TCGA;COSMIC	9.540	Up-regulation
Atypical_PIKK_ATM_ATM_ST	Q15109	AGER	Q13315	ATM	T195	P196A	196	Missense	proximal	1	no	9.967	7.896	EPSD	TCGA;ICGC;COSMIC	9.540	Loss
Atypical_PIKK_ATM_ATM_ST	Q15109	AGER	Q13315	ATM	T195	P202S	202	Missense	distal	7	no	9.967	9.948	EPSD	TCGA;ICGC;COSMIC	9.540	Down-regulation
Atypical_PIKK_ATM_ATM_ST	Q15109	AGER	Q13315	ATM	T195	D201N	201	Missense	distal	6	no	9.967	9.979	EPSD	TCGA;ICGC;COSMIC	9.540	Up-regulation
Atypical_PIKK_ATM_ATM_ST	Q15109	AGER	Q13315	ATM	T195	S190L	190	Missense	distal	-5	no	9.967	9.990	EPSD	TCGA;COSMIC	9.540	Up-regulation
Atypical_PIKK_ATM_ATM_ST	Q15109	AGER	Q13315	ATM	S391	S391L	391	Missense	central	0	yes	11.086	0.000	PhosphoSitePlus	TCGA;COSMIC	9.540	Loss
Atypical_PIKK_ATM_ATM_ST	Q15109	AGER	Q13315	ATM	S391	E395K	395	Missense	distal	4	no	11.086	11.464	PhosphoSitePlus	TCGA;COSMIC	9.540	Up-regulation
Atypical_PIKK_ATM_ATM_ST	Q15109	AGER	Q13315	ATM	S391	R385C	385	Missense	distal	-6	no	11.086	10.887	PhosphoSitePlus	TCGA;COSMIC	9.540	Down-regulation
Atypical_PIKK_ATM_ATM_ST	Q15109	AGER	Q13315	ATM	S391	E395D	395	Missense	distal	4	no	11.086	11.592	PhosphoSitePlus	TCGA;COSMIC	9.540	Up-regulation
Atypical_PIKK_ATM_ATM_ST	Q99638	RAD9A	Q13315	ATM	S272	S266L	266	Missense	distal	-6	no	14.144	13.856	PhosphoSitePlus	TCGA;ICGC;COSMIC;GDSC;CCLE	9.540	Down-regulation
Atypical_PIKK_ATM_ATM_ST	Q99638	RAD9A	Q13315	ATM	S272	D274N	274	Missense	proximal	2	no	14.144	13.123	PhosphoSitePlus	TCGA;ICGC;COSMIC;GDSC;CCLE	9.540	Down-regulation
Atypical_PIKK_ATM_ATM_ST	P40692	MLH1	Q13315	ATM	S406	L404M	404	Missense	proximal	-2	no	15.006	14.957	PhosphoSitePlus	TCGA	9.540	Down-regulation
Atypical_PIKK_ATM_ATM_ST	P40692	MLH1	Q13315	ATM	S406	S405F	405	Missense	proximal	-1	no	15.006	14.580	PhosphoSitePlus	TCGA;COSMIC	9.540	Down-regulation
Atypical_PIKK_ATM_ATM_ST	P40692	MLH1	Q13315	ATM	S406	Q409H	409	Missense	distal	3	no	15.006	15.146	PhosphoSitePlus	TCGA	9.540	Up-regulation
Atypical_PIKK_ATM_ATM_ST	P40692	MLH1	Q13315	ATM	S692	S695L	695	Missense	distal	3	no	10.216	10.498	EPSD	TCGA;COSMIC	9.540	Up-regulation
Atypical_PIKK_ATM_ATM_ST	O43683	BUB1	Q13315	ATM	S224	V221M	221	Missense	distal	-3	no	9.940	9.877	EPSD	TCGA;ICGC;COSMIC	9.540	Down-regulation
Atypical_PIKK_ATM_ATM_ST	O43683	BUB1	Q13315	ATM	S314	R317G	317	Missense	distal	3	no	14.746	14.691	PhosphoSitePlus	TCGA;ICGC;COSMIC	9.540	Down-regulation
Atypical_PIKK_ATM_ATM_ST	O43683	BUB1	Q13315	ATM	S331	A337V	337	Missense	distal	6	no	14.645	14.615	EPSD	TCGA;ICGC;COSMIC;CCLE	9.540	Down-regulation
Atypical_PIKK_ATM_ATM_ST	O43683	BUB1	Q13315	ATM	S379	A377T	377	Missense	proximal	-2	no	16.400	16.500	EPSD	TCGA;ICGC;COSMIC	9.540	Up-regulation
Atypical_PIKK_ATM_ATM_ST	O43683	BUB1	Q13315	ATM	S379	T378A	378	Missense	proximal	-1	no	16.400	16.229	EPSD	TCGA;COSMIC	9.540	Down-regulation
Atypical_PIKK_ATM_ATM_ST	O43683	BUB1	Q13315	ATM	S379	P384S	384	Missense	distal	5	no	16.400	16.219	EPSD	TCGA	9.540	Down-regulation
Atypical_PIKK_ATM_ATM_ST	O43683	BUB1	Q13315	ATM	T441	M448V	448	Missense	distal	7	no	9.809	9.824	EPSD	TCGA;ICGC;COSMIC	9.540	Up-regulation
Atypical_PIKK_ATM_ATM_ST	O43683	BUB1	Q13315	ATM	T441	S437Y	437	Missense	distal	-4	no	9.809	8.708	EPSD	TCGA;ICGC;COSMIC	9.540	Loss
Atypical_PIKK_ATM_ATM_ST	O43683	BUB1	Q13315	ATM	S459	V462A	462	Missense	distal	3	no	12.629	12.341	EPSD	TCGA;ICGC;COSMIC	9.540	Down-regulation
Atypical_PIKK_ATM_ATM_ST	O43683	BUB1	Q13315	ATM	S459	T452M	452	Missense	distal	-7	no	12.629	12.235	EPSD	TCGA;ICGC;COSMIC;CCLE	9.540	Down-regulation
Atypical_PIKK_ATM_ATM_ST	O43683	BUB1	Q13315	ATM	S459	S459P	459	Missense	central	0	yes	12.629	0.000	EPSD	TCGA;ICGC;COSMIC	9.540	Loss
Atypical_PIKK_ATM_ATM_ST	O43683	BUB1	Q13315	ATM	S563	E568K	568	Missense	distal	5	no	9.492	9.667	EPSD	TCGA;COSMIC	9.540	Gain
Atypical_PIKK_ATM_ATM_ST	O43683	BUB1	Q13315	ATM	S563	P562S	562	Missense	proximal	-1	no	9.492	9.785	EPSD	TCGA;ICGC;COSMIC;CCLE	9.540	Gain
Atypical_PIKK_ATM_ATM_ST	O43683	BUB1	Q13315	ATM	S596	S602C	602	Missense	distal	6	no	10.601	10.529	EPSD	TCGA;ICGC;COSMIC	9.540	Down-regulation
Atypical_PIKK_ATM_ATM_ST	O43683	BUB1	Q13315	ATM	T609	S602C	602	Missense	distal	-7	no	11.186	10.512	EPSD	TCGA;ICGC;COSMIC	9.540	Down-regulation
Atypical_PIKK_ATM_ATM_ST	O43683	BUB1	Q13315	ATM	T634	C641F	641	Missense	distal	7	no	13.650	13.658	EPSD	TCGA;ICGC;COSMIC	9.540	Up-regulation
Atypical_PIKK_ATM_ATM_ST	O43683	BUB1	Q13315	ATM	T634	V628M	628	Missense	distal	-6	no	13.650	13.661	EPSD	TCGA;ICGC	9.540	Up-regulation
Atypical_PIKK_ATM_ATM_ST	O43683	BUB1	Q13315	ATM	T634	S640Y	640	Missense	distal	6	no	13.650	13.609	EPSD	TCGA;ICGC	9.540	Down-regulation
Atypical_PIKK_ATM_ATM_ST	O43683	BUB1	Q13315	ATM	S679	R677C	677	Missense	proximal	-2	no	13.608	13.589	EPSD	TCGA;ICGC;COSMIC	9.540	Down-regulation
Atypical_PIKK_ATM_ATM_ST	O00213	APBB1	Q13315	ATM	S118	G112D	112	Missense	distal	-6	no	9.921	10.096	EPSD	TCGA;ICGC;COSMIC	9.540	Up-regulation
Atypical_PIKK_ATM_ATM_ST	O00213	APBB1	Q13315	ATM	S118	S118F	118	Missense	central	0	yes	9.921	0.000	EPSD	TCGA;ICGC;COSMIC	9.540	Loss
Atypical_PIKK_ATM_ATM_ST	O00213	APBB1	Q13315	ATM	S118	Y117H	117	Missense	proximal	-1	no	9.921	9.766	EPSD	TCGA;ICGC;COSMIC;GDSC;CCLE	9.540	Down-regulation
Atypical_PIKK_ATM_ATM_ST	O00213	APBB1	Q13315	ATM	S175	E181D	181	Missense	distal	6	no	12.943	12.896	EPSD	TCGA;ICGC;COSMIC	9.540	Down-regulation
Atypical_PIKK_ATM_ATM_ST	O00213	APBB1	Q13315	ATM	S228	S233C	233	Missense	distal	5	no	13.546	13.773	PhosphoSitePlus	TCGA;ICGC;COSMIC	9.540	Up-regulation
Atypical_PIKK_ATM_ATM_ST	O00213	APBB1	Q13315	ATM	S228	W224G	224	Missense	distal	-4	no	13.546	14.044	PhosphoSitePlus	TCGA;ICGC;COSMIC	9.540	Up-regulation
Atypical_PIKK_ATM_ATM_ST	O00213	APBB1	Q13315	ATM	S228	S228F	228	Missense	central	0	yes	13.546	0.000	PhosphoSitePlus	TCGA;ICGC;COSMIC	9.540	Loss
Atypical_PIKK_ATM_ATM_ST	O00213	APBB1	Q13315	ATM	S289	P288L	288	Missense	proximal	-1	no	15.539	15.697	EPSD	TCGA;COSMIC	9.540	Up-regulation
Atypical_PIKK_ATM_ATM_ST	O00213	APBB1	Q13315	ATM	S289	G284V	284	Missense	distal	-5	no	15.539	15.598	EPSD	TCGA	9.540	Up-regulation
Atypical_PIKK_ATM_ATM_ST	O00213	APBB1	Q13315	ATM	S289	R285W	285	Missense	distal	-4	no	15.539	15.064	EPSD	TCGA;COSMIC	9.540	Down-regulation
Atypical_PIKK_ATM_ATM_ST	O00213	APBB1	Q13315	ATM	S289	P288S	288	Missense	proximal	-1	no	15.539	15.832	EPSD	TCGA;COSMIC	9.540	Up-regulation
Atypical_PIKK_ATM_ATM_ST	O00213	APBB1	Q13315	ATM	S289	G284S	284	Missense	distal	-5	no	15.539	15.485	EPSD	TCGA;COSMIC	9.540	Down-regulation
Atypical_PIKK_ATM_ATM_ST	O00213	APBB1	Q13315	ATM	S322	W317R	317	Missense	distal	-5	no	9.628	9.463	EPSD	TCGA;COSMIC	9.540	Loss
Atypical_PIKK_ATM_ATM_ST	O00213	APBB1	Q13315	ATM	S322	K318N	318	Missense	distal	-4	no	9.628	9.393	EPSD	TCGA	9.540	Loss
Atypical_PIKK_ATM_ATM_ST	Q86U86	PBRM1	Q13315	ATM	S10	G17R	17	Missense	distal	7	no	10.980	10.973	EPSD	TCGA;ICGC;COSMIC	9.540	Down-regulation
Atypical_PIKK_ATM_ATM_ST	Q86U86	PBRM1	Q13315	ATM	S178	L182F	182	Missense	distal	4	no	11.661	12.148	EPSD	TCGA;ICGC	9.540	Up-regulation
Atypical_PIKK_ATM_ATM_ST	Q86U86	PBRM1	Q13315	ATM	S178	E184D	184	Missense	distal	6	no	11.661	11.615	EPSD	TCGA;ICGC;COSMIC	9.540	Down-regulation
Atypical_PIKK_ATM_ATM_ST	Q86U86	PBRM1	Q13315	ATM	S178	P179S	179	Missense	proximal	1	no	11.661	4.686	EPSD	TCGA;ICGC;COSMIC	9.540	Loss
Atypical_PIKK_ATM_ATM_ST	Q86U86	PBRM1	Q13315	ATM	S371	E372Q	372	Missense	proximal	1	no	11.033	16.930	EPSD	TCGA;ICGC;COSMIC	9.540	Up-regulation
Atypical_PIKK_ATM_ATM_ST	Q86U86	PBRM1	Q13315	ATM	S371	I376M	376	Missense	distal	5	no	11.033	11.008	EPSD	TCGA;ICGC;COSMIC	9.540	Down-regulation
Atypical_PIKK_ATM_ATM_ST	Q86U86	PBRM1	Q13315	ATM	S371	R365C	365	Missense	distal	-6	no	11.033	10.834	EPSD	TCGA;ICGC;COSMIC	9.540	Down-regulation
Atypical_PIKK_ATM_ATM_ST	Q86U86	PBRM1	Q13315	ATM	S413	E406K	406	Missense	distal	-7	no	9.998	9.330	EPSD	TCGA;ICGC;COSMIC	9.540	Loss
Atypical_PIKK_ATM_ATM_ST	Q86U86	PBRM1	Q13315	ATM	S413	K414N	414	Missense	proximal	1	no	9.998	6.985	EPSD	TCGA;ICGC;COSMIC	9.540	Loss
Atypical_PIKK_ATM_ATM_ST	Q86U86	PBRM1	Q13315	ATM	S413	P412L	412	Missense	proximal	-1	no	9.998	10.155	EPSD	TCGA;ICGC;COSMIC	9.540	Up-regulation
Atypical_PIKK_ATM_ATM_ST	Q86U86	PBRM1	Q13315	ATM	S413	Y417H	417	Missense	distal	4	no	9.998	9.812	EPSD	TCGA;ICGC	9.540	Down-regulation
Atypical_PIKK_ATM_ATM_ST	Q86U86	PBRM1	Q13315	ATM	S502	I500S	500	Missense	proximal	-2	no	9.054	9.744	EPSD	TCGA;ICGC	9.540	Gain
Atypical_PIKK_ATM_ATM_ST	Q86U86	PBRM1	Q13315	ATM	S605	S605F	605	Missense	central	0	yes	14.316	0.000	EPSD	TCGA;ICGC;COSMIC	9.540	Loss
Atypical_PIKK_ATM_ATM_ST	Q86U86	PBRM1	Q13315	ATM	S605	N601K	601	Missense	distal	-4	no	14.316	14.551	EPSD	TCGA;ICGC;COSMIC	9.540	Up-regulation
Atypical_PIKK_ATM_ATM_ST	Q86U86	PBRM1	Q13315	ATM	S605	V607I	607	Missense	proximal	2	no	14.316	14.523	EPSD	TCGA;ICGC	9.540	Up-regulation
Atypical_PIKK_ATM_ATM_ST	Q86U86	PBRM1	Q13315	ATM	S681	R679H	679	Missense	proximal	-2	no	11.273	11.289	EPSD	TCGA;ICGC;COSMIC	9.540	Up-regulation
Atypical_PIKK_ATM_ATM_ST	Q86U86	PBRM1	Q13315	ATM	S1280	L1279F	1279	Missense	proximal	-1	no	12.779	12.487	EPSD	TCGA;COSMIC	9.540	Down-regulation
Atypical_PIKK_ATM_ATM_ST	Q99504	EYA3	Q13315	ATM	S256	S256C	256	Missense	central	0	yes	10.141	0.000	EPSD	TCGA;COSMIC	9.540	Loss
Atypical_PIKK_ATM_ATM_ST	Q99504	EYA3	Q13315	ATM	S256	S255F	255	Missense	proximal	-1	no	10.141	9.714	EPSD	TCGA;COSMIC	9.540	Down-regulation
Atypical_PIKK_ATM_ATM_ST	Q99504	EYA3	Q13315	ATM	S262	S256C	256	Missense	distal	-6	no	10.966	10.586	EPSD	TCGA;COSMIC	9.540	Down-regulation
Atypical_PIKK_ATM_ATM_ST	Q99504	EYA3	Q13315	ATM	S262	S255F	255	Missense	distal	-7	no	10.966	10.136	EPSD	TCGA;COSMIC	9.540	Down-regulation
Atypical_PIKK_ATM_ATM_ST	Q99504	EYA3	Q13315	ATM	S297	R304W	304	Missense	distal	7	no	16.215	16.241	EPSD	TCGA;COSMIC	9.540	Up-regulation
Atypical_PIKK_ATM_ATM_ST	Q8TAQ2	SMARCC2	Q13315	ATM	S302	S304C	304	Missense	proximal	2	no	9.542	8.288	EPSD	TCGA;ICGC;COSMIC	9.540	Loss
Atypical_PIKK_ATM_ATM_ST	Q8TAQ2	SMARCC2	Q13315	ATM	S302	S306L	306	Missense	distal	4	no	9.542	9.884	EPSD	TCGA;ICGC;COSMIC	9.540	Up-regulation
Atypical_PIKK_ATM_ATM_ST	Q8TAQ2	SMARCC2	Q13315	ATM	S302	P305A	305	Missense	distal	3	no	9.542	9.446	EPSD	TCGA;ICGC;COSMIC	9.540	Loss
Atypical_PIKK_ATM_ATM_ST	Q8TAQ2	SMARCC2	Q13315	ATM	S302	R301C	301	Missense	proximal	-1	no	9.542	9.717	EPSD	TCGA;ICGC	9.540	Up-regulation
Atypical_PIKK_ATM_ATM_ST	Q8TAQ2	SMARCC2	Q13315	ATM	S304	S304C	304	Missense	central	0	yes	10.849	0.000	EPSD	TCGA;ICGC;COSMIC	9.540	Loss
Atypical_PIKK_ATM_ATM_ST	Q8TAQ2	SMARCC2	Q13315	ATM	S304	S306L	306	Missense	proximal	2	no	10.849	9.605	EPSD	TCGA;ICGC;COSMIC	9.540	Down-regulation
Atypical_PIKK_ATM_ATM_ST	Q8TAQ2	SMARCC2	Q13315	ATM	S304	P305A	305	Missense	proximal	1	no	10.849	8.778	EPSD	TCGA;ICGC;COSMIC	9.540	Loss
Atypical_PIKK_ATM_ATM_ST	Q8TAQ2	SMARCC2	Q13315	ATM	S304	R301C	301	Missense	distal	-3	no	10.849	10.277	EPSD	TCGA;ICGC	9.540	Down-regulation
Atypical_PIKK_ATM_ATM_ST	Q8TAQ2	SMARCC2	Q13315	ATM	T308	S304C	304	Missense	distal	-4	no	10.631	9.058	EPSD	TCGA;ICGC;COSMIC	9.540	Loss
Atypical_PIKK_ATM_ATM_ST	Q8TAQ2	SMARCC2	Q13315	ATM	T308	S306L	306	Missense	proximal	-2	no	10.631	10.241	EPSD	TCGA;ICGC;COSMIC	9.540	Down-regulation
Atypical_PIKK_ATM_ATM_ST	Q8TAQ2	SMARCC2	Q13315	ATM	T308	P305A	305	Missense	distal	-3	no	10.631	9.989	EPSD	TCGA;ICGC;COSMIC	9.540	Down-regulation
Atypical_PIKK_ATM_ATM_ST	Q8TAQ2	SMARCC2	Q13315	ATM	T308	R301C	301	Missense	distal	-7	no	10.631	10.355	EPSD	TCGA;ICGC	9.540	Down-regulation
Atypical_PIKK_ATM_ATM_ST	Q8TAQ2	SMARCC2	Q13315	ATM	S369	G374D	374	Missense	distal	5	no	9.822	9.731	EPSD	TCGA;ICGC;COSMIC	9.540	Down-regulation
Atypical_PIKK_ATM_ATM_ST	Q8TAQ2	SMARCC2	Q13315	ATM	S369	D366G	366	Missense	distal	-3	no	9.822	9.855	EPSD	TCGA;ICGC	9.540	Up-regulation
Atypical_PIKK_ATM_ATM_ST	Q8TAQ2	SMARCC2	Q13315	ATM	S369	D366Y	366	Missense	distal	-3	no	9.822	9.709	EPSD	TCGA;ICGC	9.540	Down-regulation
Atypical_PIKK_ATM_ATM_ST	Q8TAQ2	SMARCC2	Q13315	ATM	S555	S553F	553	Missense	proximal	-2	no	14.022	13.122	EPSD	TCGA;ICGC;COSMIC	9.540	Down-regulation
Atypical_PIKK_ATM_ATM_ST	Q8TAQ2	SMARCC2	Q13315	ATM	S555	T552I	552	Missense	distal	-3	no	14.022	14.760	EPSD	TCGA;ICGC;COSMIC	9.540	Up-regulation
Atypical_PIKK_ATM_ATM_ST	Q8TAQ2	SMARCC2	Q13315	ATM	S969	T975I	975	Missense	distal	6	no	13.793	13.762	PhosphoSitePlus	TCGA;ICGC;COSMIC	9.540	Down-regulation
Atypical_PIKK_ATM_ATM_ST	Q8TAQ2	SMARCC2	Q13315	ATM	S969	P974S	974	Missense	distal	5	no	13.793	13.611	PhosphoSitePlus	TCGA;ICGC;COSMIC	9.540	Down-regulation
Atypical_PIKK_ATM_ATM_ST	Q15797	SMAD1	Q13315	ATM	S239	Q236R	236	Missense	distal	-3	no	14.556	15.331	PhosphoSitePlus	TCGA;ICGC;COSMIC	9.540	Up-regulation
Atypical_PIKK_ATM_ATM_ST	Q15797	SMAD1	Q13315	ATM	S239	D232H	232	Missense	distal	-7	no	14.556	14.466	PhosphoSitePlus	TCGA;ICGC;COSMIC	9.540	Down-regulation
Atypical_PIKK_ATM_ATM_ST	Q15797	SMAD1	Q13315	ATM	S463	V464L	464	Missense	proximal	1	no	3.260	9.898	EPSD	TCGA;ICGC;COSMIC	9.540	Gain
Atypical_PIKK_ATM_ATM_ST	P55072	VCP	Q13315	ATM	S78	M84I	84	Missense	distal	6	no	10.334	10.322	EPSD	TCGA	9.540	Down-regulation
Atypical_PIKK_ATM_ATM_ST	P55072	VCP	Q13315	ATM	S78	R83Q	83	Missense	distal	5	no	10.334	10.222	EPSD	TCGA;ICGC;COSMIC	9.540	Down-regulation
Atypical_PIKK_ATM_ATM_ST	P55072	VCP	Q13315	ATM	S326	S326L	326	Missense	central	0	yes	14.782	0.000	PhosphoSitePlus	TCGA;ICGC;COSMIC	9.540	Loss
Atypical_PIKK_ATM_ATM_ST	P55072	VCP	Q13315	ATM	S326	R323H	323	Missense	distal	-3	no	14.782	14.137	PhosphoSitePlus	TCGA;ICGC;COSMIC;GDSC;CCLE	9.540	Down-regulation
Atypical_PIKK_ATM_ATM_ST	P55072	VCP	Q13315	ATM	S457	R453Q	453	Missense	distal	-4	no	16.110	16.475	EPSD	TCGA;ICGC;COSMIC	9.540	Up-regulation
TK_Trk_NTRK1_Y	P35222	CTNNB1	P04629	NTRK1	Y333	Y333F	333	Missense	central	0	yes	0.000	0.000	EPSD	TCGA;COSMIC	0.000	Loss
TK_Trk_NTRK1_Y	P04629	NTRK1	P04629	NTRK1	Y701	Y701H	701	Missense	central	0	yes	0.000	0.000	EPSD	TCGA;COSMIC	0.000	Loss
TK_Trk_NTRK1_Y	P04629	NTRK1	P04629	NTRK1	Y791	Y791N	791	Missense	central	0	yes	0.000	0.000	EPSD	TCGA;COSMIC	0.000	Loss
CMGC_MAPK_p38_MAPK13_ST	O00418	EEF2K	O15264	MAPK13	S61	E67K	67	Missense	distal	6	no	39.058	39.346	EPSD	TCGA;ICGC;COSMIC	38.013	Up-regulation
CMGC_MAPK_p38_MAPK13_ST	O00418	EEF2K	O15264	MAPK13	S61	S61G	61	Missense	central	0	yes	39.058	0.000	EPSD	TCGA;ICGC	38.013	Loss
CMGC_MAPK_p38_MAPK13_ST	O00418	EEF2K	O15264	MAPK13	S61	R68W	68	Missense	distal	7	no	39.058	37.682	EPSD	TCGA	38.013	Loss
CMGC_MAPK_p38_MAPK13_ST	O00418	EEF2K	O15264	MAPK13	S61	S61I	61	Missense	central	0	yes	39.058	0.000	EPSD	TCGA;ICGC	38.013	Loss
CMGC_MAPK_p38_MAPK13_ST	O00418	EEF2K	O15264	MAPK13	S74	E67K	67	Missense	distal	-7	no	50.260	50.446	EPSD	TCGA;ICGC;COSMIC	38.013	Up-regulation
CMGC_MAPK_p38_MAPK13_ST	O00418	EEF2K	O15264	MAPK13	S74	H80Y	80	Missense	distal	6	no	50.260	49.946	EPSD	TCGA;ICGC;COSMIC	38.013	Down-regulation
CMGC_MAPK_p38_MAPK13_ST	O00418	EEF2K	O15264	MAPK13	S74	R68W	68	Missense	distal	-6	no	50.260	48.861	EPSD	TCGA	38.013	Down-regulation
CMGC_MAPK_p38_MAPK13_ST	O00418	EEF2K	O15264	MAPK13	S74	S74C	74	Missense	central	0	yes	50.260	0.000	EPSD	TCGA;ICGC;COSMIC	38.013	Loss
CMGC_MAPK_p38_MAPK13_ST	O00418	EEF2K	O15264	MAPK13	S359	S366F	366	Missense	distal	7	no	53.316	51.918	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	38.013	Down-regulation
CMGC_MAPK_p38_MAPK13_ST	O00418	EEF2K	O15264	MAPK13	S359	S366C	366	Missense	distal	7	no	53.316	51.624	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	38.013	Down-regulation
CMGC_MAPK_p38_MAPK13_ST	O00418	EEF2K	O15264	MAPK13	S386	D387N	387	Missense	proximal	1	no	20.198	40.622	EPSD	TCGA;ICGC	38.013	Gain
CMGC_MAPK_p38_MAPK13_ST	O00418	EEF2K	O15264	MAPK13	S396	A400V	400	Missense	distal	4	no	51.905	51.942	PhosphoSitePlus;EPSD	TCGA;ICGC;COSMIC	38.013	Up-regulation
CMGC_MAPK_p38_MAPK13_ST	O00418	EEF2K	O15264	MAPK13	S396	S396F	396	Missense	central	0	yes	51.905	0.000	PhosphoSitePlus;EPSD	TCGA;ICGC;COSMIC	38.013	Loss
CMGC_MAPK_p38_MAPK13_ST	O00418	EEF2K	O15264	MAPK13	S396	S392F	392	Missense	distal	-4	no	51.905	49.049	PhosphoSitePlus;EPSD	TCGA;ICGC;COSMIC	38.013	Down-regulation
CMGC_MAPK_p38_MAPK13_ST	O00418	EEF2K	O15264	MAPK13	S396	D391N	391	Missense	distal	-5	no	51.905	51.914	PhosphoSitePlus;EPSD	TCGA;ICGC	38.013	Up-regulation
CMGC_MAPK_p38_MAPK13_ST	O00418	EEF2K	O15264	MAPK13	S399	A400V	400	Missense	proximal	1	no	27.398	46.904	EPSD	TCGA;ICGC;COSMIC	38.013	Gain
CMGC_MAPK_p38_MAPK13_ST	O00418	EEF2K	O15264	MAPK13	T401	A400V	400	Missense	proximal	-1	no	46.484	46.839	EPSD	TCGA;ICGC;COSMIC	38.013	Up-regulation
CMGC_MAPK_p38_MAPK13_ST	O00418	EEF2K	O15264	MAPK13	T401	S396F	396	Missense	distal	-5	no	46.484	47.213	EPSD	TCGA;ICGC;COSMIC	38.013	Up-regulation
CMGC_MAPK_p38_MAPK13_ST	O00418	EEF2K	O15264	MAPK13	S404	A400V	400	Missense	distal	-4	no	47.258	46.933	EPSD	TCGA;ICGC;COSMIC	38.013	Down-regulation
CMGC_MAPK_p38_MAPK13_ST	O00418	EEF2K	O15264	MAPK13	S474	E472K	472	Missense	proximal	-2	no	37.105	38.391	EPSD	TCGA;ICGC	38.013	Gain
CMGC_MAPK_p38_MAPK13_ST	O00418	EEF2K	O15264	MAPK13	S627	D621N	621	Missense	distal	-6	no	37.639	38.086	EPSD	TCGA;ICGC;COSMIC	38.013	Gain
CMGC_MAPK_p38_MAPK13_ST	P10636	MAPT	O15264	MAPK13	S46	T52I	52	Missense	distal	6	no	46.241	45.669	EPSD	TCGA;ICGC;COSMIC	38.013	Down-regulation
CMGC_MAPK_p38_MAPK13_ST	P10636	MAPT	O15264	MAPK13	S46	P47S	47	Missense	proximal	1	no	46.241	20.689	EPSD	TCGA;ICGC;COSMIC	38.013	Loss
CMGC_MAPK_p38_MAPK13_ST	P10636	MAPT	O15264	MAPK13	S46	P47L	47	Missense	proximal	1	no	46.241	33.808	EPSD	TCGA;ICGC;COSMIC	38.013	Loss
CMGC_MAPK_p38_MAPK13_ST	P10636	MAPT	O15264	MAPK13	S46	G42C	42	Missense	distal	-4	no	46.241	44.143	EPSD	TCGA;ICGC;COSMIC	38.013	Down-regulation
CMGC_MAPK_p38_MAPK13_ST	P10636	MAPT	O15264	MAPK13	T50	D54E	54	Missense	distal	4	no	55.525	54.584	EPSD	TCGA;ICGC;COSMIC	38.013	Down-regulation
CMGC_MAPK_p38_MAPK13_ST	P10636	MAPT	O15264	MAPK13	T50	T52I	52	Missense	proximal	2	no	55.525	51.753	EPSD	TCGA;ICGC;COSMIC	38.013	Down-regulation
CMGC_MAPK_p38_MAPK13_ST	P10636	MAPT	O15264	MAPK13	T50	P47S	47	Missense	distal	-3	no	55.525	55.485	EPSD	TCGA;ICGC;COSMIC	38.013	Down-regulation
CMGC_MAPK_p38_MAPK13_ST	P10636	MAPT	O15264	MAPK13	T50	P47L	47	Missense	distal	-3	no	55.525	54.489	EPSD	TCGA;ICGC;COSMIC	38.013	Down-regulation
CMGC_MAPK_p38_MAPK13_ST	P10636	MAPT	O15264	MAPK13	T50	G55R	55	Missense	distal	5	no	55.525	56.023	EPSD	TCGA;ICGC;COSMIC	38.013	Up-regulation
CMGC_MAPK_p38_MAPK13_ST	P10636	MAPT	O15264	MAPK13	T69	A72V	72	Missense	distal	3	no	55.747	55.739	EPSD	TCGA;ICGC;COSMIC	38.013	Down-regulation
CMGC_MAPK_p38_MAPK13_ST	P10636	MAPT	O15264	MAPK13	T69	A66S	66	Missense	distal	-3	no	55.747	56.725	EPSD	TCGA;ICGC;COSMIC	38.013	Up-regulation
CMGC_MAPK_p38_MAPK13_ST	P10636	MAPT	O15264	MAPK13	T71	A72V	72	Missense	proximal	1	no	20.517	40.023	EPSD	TCGA;ICGC;COSMIC	38.013	Gain
CMGC_MAPK_p38_MAPK13_ST	P10636	MAPT	O15264	MAPK13	T111	E117K	117	Missense	distal	6	no	38.311	38.598	EPSD	TCGA;ICGC;COSMIC	38.013	Up-regulation
CMGC_MAPK_p38_MAPK13_ST	P10636	MAPT	O15264	MAPK13	T111	A118V	118	Missense	distal	7	no	38.311	38.844	EPSD	TCGA;ICGC;COSMIC	38.013	Up-regulation
CMGC_MAPK_p38_MAPK13_ST	P10636	MAPT	O15264	MAPK13	S228	S232Y	232	Missense	distal	4	no	46.272	45.249	EPSD	TCGA;ICGC;COSMIC	38.013	Down-regulation
CMGC_MAPK_p38_MAPK13_ST	P10636	MAPT	O15264	MAPK13	S228	D223Y	223	Missense	distal	-5	no	46.272	46.649	EPSD	TCGA;ICGC;COSMIC	38.013	Up-regulation
CMGC_MAPK_p38_MAPK13_ST	P10636	MAPT	O15264	MAPK13	S228	S227F	227	Missense	proximal	-1	no	46.272	45.466	EPSD	TCGA;ICGC;COSMIC	38.013	Down-regulation
CMGC_MAPK_p38_MAPK13_ST	P10636	MAPT	O15264	MAPK13	S228	P234L	234	Missense	distal	6	no	46.272	45.801	EPSD	TCGA;ICGC;COSMIC	38.013	Down-regulation
CMGC_MAPK_p38_MAPK13_ST	P10636	MAPT	O15264	MAPK13	S232	S232Y	232	Missense	central	0	yes	50.046	0.000	EPSD	TCGA;ICGC;COSMIC	38.013	Loss
CMGC_MAPK_p38_MAPK13_ST	P10636	MAPT	O15264	MAPK13	S232	S227F	227	Missense	distal	-5	no	50.046	50.775	EPSD	TCGA;ICGC;COSMIC	38.013	Up-regulation
CMGC_MAPK_p38_MAPK13_ST	P10636	MAPT	O15264	MAPK13	S232	P234L	234	Missense	proximal	2	no	50.046	49.418	EPSD	TCGA;ICGC;COSMIC	38.013	Down-regulation
CMGC_MAPK_p38_MAPK13_ST	P10636	MAPT	O15264	MAPK13	S238	S232Y	232	Missense	distal	-6	no	52.512	51.644	EPSD	TCGA;ICGC;COSMIC	38.013	Down-regulation
CMGC_MAPK_p38_MAPK13_ST	P10636	MAPT	O15264	MAPK13	S238	A240T	240	Missense	proximal	2	no	52.512	55.861	EPSD	TCGA;ICGC;COSMIC	38.013	Up-regulation
CMGC_MAPK_p38_MAPK13_ST	P10636	MAPT	O15264	MAPK13	S238	P234L	234	Missense	distal	-4	no	52.512	50.540	EPSD	TCGA;ICGC;COSMIC	38.013	Down-regulation
CMGC_MAPK_p38_MAPK13_ST	P10636	MAPT	O15264	MAPK13	S238	R244Q	244	Missense	distal	6	no	52.512	52.319	EPSD	TCGA;ICGC;COSMIC	38.013	Down-regulation
CMGC_MAPK_p38_MAPK13_ST	P10636	MAPT	O15264	MAPK13	T386	G387R	387	Missense	proximal	1	no	-28.427	42.782	EPSD	TCGA;COSMIC	38.013	Gain
CMGC_MAPK_p38_MAPK13_ST	P10636	MAPT	O15264	MAPK13	S411	P415L	415	Missense	distal	4	no	52.055	50.829	EPSD	TCGA;ICGC;COSMIC	38.013	Down-regulation
CMGC_MAPK_p38_MAPK13_ST	P10636	MAPT	O15264	MAPK13	T416	P415L	415	Missense	proximal	-1	no	50.749	50.116	EPSD	TCGA;ICGC;COSMIC	38.013	Down-regulation
CMGC_MAPK_p38_MAPK13_ST	P10636	MAPT	O15264	MAPK13	S428	A430S	430	Missense	proximal	2	no	51.416	53.320	EPSD	TCGA;ICGC;COSMIC	38.013	Up-regulation
CMGC_MAPK_p38_MAPK13_ST	P10636	MAPT	O15264	MAPK13	S428	V431L	431	Missense	distal	3	no	51.416	51.234	EPSD	TCGA;ICGC;COSMIC	38.013	Down-regulation
CMGC_MAPK_p38_MAPK13_ST	P10636	MAPT	O15264	MAPK13	S428	A430V	430	Missense	proximal	2	no	51.416	53.686	EPSD	TCGA;ICGC;COSMIC	38.013	Up-regulation
CMGC_MAPK_p38_MAPK13_ST	P10636	MAPT	O15264	MAPK13	S438	P436T	436	Missense	proximal	-2	no	49.548	49.285	EPSD	TCGA;ICGC;COSMIC	38.013	Down-regulation
CMGC_MAPK_p38_MAPK13_ST	P10636	MAPT	O15264	MAPK13	S438	P436L	436	Missense	proximal	-2	no	49.548	48.019	EPSD	TCGA;ICGC;COSMIC	38.013	Down-regulation
CMGC_MAPK_p38_MAPK13_ST	P10636	MAPT	O15264	MAPK13	S438	K440E	440	Missense	proximal	2	no	49.548	48.478	EPSD	TCGA;ICGC;COSMIC	38.013	Down-regulation
CMGC_MAPK_p38_MAPK13_ST	P10636	MAPT	O15264	MAPK13	S438	S443F	443	Missense	distal	5	no	49.548	48.969	EPSD	TCGA;ICGC;COSMIC	38.013	Down-regulation
CMGC_MAPK_p38_MAPK13_ST	P10636	MAPT	O15264	MAPK13	S438	V431L	431	Missense	distal	-7	no	49.548	49.024	EPSD	TCGA;ICGC;COSMIC	38.013	Down-regulation
CMGC_MAPK_p38_MAPK13_ST	P10636	MAPT	O15264	MAPK13	S438	S444F	444	Missense	distal	6	no	49.548	49.044	EPSD	TCGA;ICGC	38.013	Down-regulation
CMGC_MAPK_p38_MAPK13_ST	P10636	MAPT	O15264	MAPK13	S447	K440E	440	Missense	distal	-7	no	43.110	42.924	EPSD	TCGA;ICGC;COSMIC	38.013	Down-regulation
CMGC_MAPK_p38_MAPK13_ST	P10636	MAPT	O15264	MAPK13	S447	S452C	452	Missense	distal	5	no	43.110	42.328	EPSD	TCGA;ICGC;COSMIC	38.013	Down-regulation
CMGC_MAPK_p38_MAPK13_ST	P10636	MAPT	O15264	MAPK13	S447	S443F	443	Missense	distal	-4	no	43.110	40.254	EPSD	TCGA;ICGC;COSMIC	38.013	Down-regulation
CMGC_MAPK_p38_MAPK13_ST	P10636	MAPT	O15264	MAPK13	S447	S444F	444	Missense	distal	-3	no	43.110	41.871	EPSD	TCGA;ICGC	38.013	Down-regulation
CMGC_MAPK_p38_MAPK13_ST	P10636	MAPT	O15264	MAPK13	S447	S452Y	452	Missense	distal	5	no	43.110	42.649	EPSD	TCGA;ICGC;COSMIC	38.013	Down-regulation
CMGC_MAPK_p38_MAPK13_ST	P10636	MAPT	O15264	MAPK13	T470	R472Q	472	Missense	proximal	2	no	55.325	53.736	EPSD	TCGA	38.013	Down-regulation
CMGC_MAPK_p38_MAPK13_ST	P10636	MAPT	O15264	MAPK13	T470	R472W	472	Missense	proximal	2	no	55.325	51.457	EPSD	TCGA;COSMIC	38.013	Down-regulation
CMGC_MAPK_p38_MAPK13_ST	P10636	MAPT	O15264	MAPK13	T486	A485T	485	Missense	proximal	-1	no	40.318	41.153	EPSD	TCGA;COSMIC;GDSC;CCLE	38.013	Up-regulation
CMGC_MAPK_p38_MAPK13_ST	P10636	MAPT	O15264	MAPK13	T486	Q479H	479	Missense	distal	-7	no	40.318	38.378	EPSD	TCGA;COSMIC	38.013	Down-regulation
CMGC_MAPK_p38_MAPK13_ST	P10636	MAPT	O15264	MAPK13	T486	P493Q	493	Missense	distal	7	no	40.318	39.811	EPSD	TCGA;COSMIC	38.013	Down-regulation
CMGC_MAPK_p38_MAPK13_ST	P10636	MAPT	O15264	MAPK13	T492	A485T	485	Missense	distal	-7	no	46.786	49.475	EPSD	TCGA;COSMIC;GDSC;CCLE	38.013	Up-regulation
CMGC_MAPK_p38_MAPK13_ST	P10636	MAPT	O15264	MAPK13	T492	P493Q	493	Missense	proximal	1	no	46.786	38.124	EPSD	TCGA;COSMIC	38.013	Down-regulation
CMGC_MAPK_p38_MAPK13_ST	P10636	MAPT	O15264	MAPK13	T498	P493Q	493	Missense	distal	-5	no	42.899	42.685	EPSD	TCGA;COSMIC	38.013	Down-regulation
CMGC_MAPK_p38_MAPK13_ST	Q00613	HSF1	O15264	MAPK13	S121	E128K	128	Missense	distal	7	no	43.545	44.342	EPSD	TCGA;COSMIC	38.013	Up-regulation
CMGC_MAPK_p38_MAPK13_ST	Q00613	HSF1	O15264	MAPK13	S121	L125M	125	Missense	distal	4	no	43.545	44.152	EPSD	TCGA;COSMIC	38.013	Up-regulation
CMGC_MAPK_p38_MAPK13_ST	Q00613	HSF1	O15264	MAPK13	T124	E128K	128	Missense	distal	4	no	40.741	41.985	EPSD	TCGA;COSMIC	38.013	Up-regulation
CMGC_MAPK_p38_MAPK13_ST	Q00613	HSF1	O15264	MAPK13	T124	I130V	130	Missense	distal	6	no	40.741	41.017	EPSD	TCGA;COSMIC	38.013	Up-regulation
CMGC_MAPK_p38_MAPK13_ST	Q00613	HSF1	O15264	MAPK13	T124	L125M	125	Missense	proximal	1	no	40.741	6.403	EPSD	TCGA;COSMIC	38.013	Loss
CMGC_MAPK_p38_MAPK13_ST	Q00613	HSF1	O15264	MAPK13	S244	S250C	250	Missense	distal	6	no	43.089	42.319	EPSD	TCGA;COSMIC	38.013	Down-regulation
CMGC_MAPK_p38_MAPK13_ST	Q00613	HSF1	O15264	MAPK13	S275	P276L	276	Missense	proximal	1	no	42.780	30.347	EPSD	TCGA;COSMIC	38.013	Loss
CMGC_MAPK_p38_MAPK13_ST	Q00613	HSF1	O15264	MAPK13	S275	M277V	277	Missense	proximal	2	no	42.780	44.930	EPSD	TCGA;COSMIC	38.013	Up-regulation
CMGC_MAPK_p38_MAPK13_ST	Q00613	HSF1	O15264	MAPK13	S279	P276L	276	Missense	distal	-3	no	43.061	42.025	EPSD	TCGA;COSMIC	38.013	Down-regulation
CMGC_MAPK_p38_MAPK13_ST	Q00613	HSF1	O15264	MAPK13	S279	E286K	286	Missense	distal	7	no	43.061	43.859	EPSD	TCGA;COSMIC	38.013	Up-regulation
CMGC_MAPK_p38_MAPK13_ST	Q00613	HSF1	O15264	MAPK13	S279	M277V	277	Missense	proximal	-2	no	43.061	44.696	EPSD	TCGA;COSMIC	38.013	Up-regulation
CMGC_MAPK_p38_MAPK13_ST	Q00613	HSF1	O15264	MAPK13	S292	R296C	296	Missense	distal	4	no	41.730	40.218	EPSD	TCGA;COSMIC	38.013	Down-regulation
CMGC_MAPK_p38_MAPK13_ST	Q00613	HSF1	O15264	MAPK13	S292	P288L	288	Missense	distal	-4	no	41.730	39.758	EPSD	TCGA;COSMIC	38.013	Down-regulation
CMGC_MAPK_p38_MAPK13_ST	Q00613	HSF1	O15264	MAPK13	S292	E286K	286	Missense	distal	-6	no	41.730	42.595	EPSD	TCGA;COSMIC	38.013	Up-regulation
CMGC_MAPK_p38_MAPK13_ST	Q00613	HSF1	O15264	MAPK13	S303	E300Q	300	Missense	distal	-3	no	55.917	56.882	EPSD;PhosphoSitePlus	TCGA	38.013	Up-regulation
CMGC_MAPK_p38_MAPK13_ST	Q00613	HSF1	O15264	MAPK13	S303	R296C	296	Missense	distal	-7	no	55.917	52.033	EPSD;PhosphoSitePlus	TCGA;COSMIC	38.013	Down-regulation
CMGC_MAPK_p38_MAPK13_ST	Q00613	HSF1	O15264	MAPK13	S307	E300Q	300	Missense	distal	-7	no	58.266	59.235	PhosphoSitePlus;EPSD	TCGA	38.013	Up-regulation
CMGC_MAPK_p38_MAPK13_ST	Q00613	HSF1	O15264	MAPK13	S314	R317H	317	Missense	distal	3	no	48.129	48.057	EPSD	TCGA;COSMIC	38.013	Down-regulation
CMGC_MAPK_p38_MAPK13_ST	Q00613	HSF1	O15264	MAPK13	S314	S320F	320	Missense	distal	6	no	48.129	47.625	EPSD	TCGA;COSMIC	38.013	Down-regulation
CMGC_MAPK_p38_MAPK13_ST	Q00613	HSF1	O15264	MAPK13	S326	D332Y	332	Missense	distal	6	no	56.945	56.678	EPSD;PhosphoSitePlus	TCGA;COSMIC	38.013	Down-regulation
CMGC_MAPK_p38_MAPK13_ST	Q00613	HSF1	O15264	MAPK13	S326	T323I	323	Missense	distal	-3	no	56.945	55.030	EPSD;PhosphoSitePlus	TCGA;COSMIC	38.013	Down-regulation
CMGC_MAPK_p38_MAPK13_ST	Q00613	HSF1	O15264	MAPK13	S326	S320F	320	Missense	distal	-6	no	56.945	55.835	EPSD;PhosphoSitePlus	TCGA;COSMIC	38.013	Down-regulation
CMGC_MAPK_p38_MAPK13_ST	Q00613	HSF1	O15264	MAPK13	S326	A329T	329	Missense	distal	3	no	56.945	57.251	EPSD;PhosphoSitePlus	TCGA;COSMIC	38.013	Up-regulation
CMGC_MAPK_p38_MAPK13_ST	Q00613	HSF1	O15264	MAPK13	S326	S333F	333	Missense	distal	7	no	56.945	55.547	EPSD;PhosphoSitePlus	TCGA;COSMIC	38.013	Down-regulation
CMGC_MAPK_p38_MAPK13_ST	Q00613	HSF1	O15264	MAPK13	S326	P327L	327	Missense	proximal	1	no	56.945	44.513	EPSD;PhosphoSitePlus	TCGA	38.013	Down-regulation
CMGC_MAPK_p38_MAPK13_ST	Q00613	HSF1	O15264	MAPK13	S344	A351T	351	Missense	distal	7	no	44.833	46.349	EPSD	TCGA;COSMIC	38.013	Up-regulation
CMGC_MAPK_p38_MAPK13_ST	Q00613	HSF1	O15264	MAPK13	S344	E339G	339	Missense	distal	-5	no	44.833	44.639	EPSD	TCGA;COSMIC	38.013	Down-regulation
CMGC_MAPK_p38_MAPK13_ST	Q00613	HSF1	O15264	MAPK13	S363	P364S	364	Missense	proximal	1	no	46.018	20.467	EPSD	TCGA;COSMIC	38.013	Loss
CMGC_MAPK_p38_MAPK13_ST	Q00613	HSF1	O15264	MAPK13	T369	P364S	364	Missense	distal	-5	no	44.201	43.891	EPSD	TCGA;COSMIC	38.013	Down-regulation
CMGC_MAPK_p38_MAPK13_ST	Q00613	HSF1	O15264	MAPK13	S419	P420L	420	Missense	proximal	1	no	52.329	39.897	EPSD	TCGA;ICGC;COSMIC	38.013	Down-regulation
CMGC_MAPK_p38_MAPK13_ST	Q00613	HSF1	O15264	MAPK13	S419	P425S	425	Missense	distal	6	no	52.329	52.392	EPSD	TCGA;ICGC;COSMIC	38.013	Up-regulation
CMGC_MAPK_p38_MAPK13_ST	Q00613	HSF1	O15264	MAPK13	S444	E441K	441	Missense	distal	-3	no	44.546	45.638	EPSD	TCGA;COSMIC	38.013	Up-regulation
CMGC_MAPK_p38_MAPK13_ST	Q00613	HSF1	O15264	MAPK13	S458	E453K	453	Missense	distal	-5	no	41.379	40.996	EPSD	TCGA;COSMIC	38.013	Down-regulation
CMGC_MAPK_p38_MAPK13_ST	P16949	STMN1	O15264	MAPK13	S25	S31Y	31	Missense	distal	6	no	47.830	47.371	PhosphoSitePlus;EPSD	TCGA;COSMIC	38.013	Down-regulation
CMGC_MAPK_p38_MAPK13_ST	P16949	STMN1	O15264	MAPK13	S25	S28P	28	Missense	distal	3	no	47.830	47.574	PhosphoSitePlus;EPSD	TCGA;ICGC	38.013	Down-regulation
CMGC_MAPK_p38_MAPK13_ST	P16949	STMN1	O15264	MAPK13	S25	K29I	29	Missense	distal	4	no	47.830	46.622	PhosphoSitePlus;EPSD	TCGA;ICGC;COSMIC	38.013	Down-regulation
CMGC_MAPK_p38_MAPK13_ST	P16949	STMN1	O15264	MAPK13	S31	S31Y	31	Missense	central	0	yes	41.372	0.000	EPSD	TCGA;COSMIC	38.013	Loss
CMGC_MAPK_p38_MAPK13_ST	P16949	STMN1	O15264	MAPK13	S31	S28P	28	Missense	distal	-3	no	41.372	41.412	EPSD	TCGA;ICGC	38.013	Up-regulation
CMGC_MAPK_p38_MAPK13_ST	P16949	STMN1	O15264	MAPK13	S31	K29I	29	Missense	proximal	-2	no	41.372	40.411	EPSD	TCGA;ICGC;COSMIC	38.013	Down-regulation
CMGC_MAPK_p38_MAPK13_ST	P16949	STMN1	O15264	MAPK13	S38	S31Y	31	Missense	distal	-7	no	52.410	51.244	EPSD;PhosphoSitePlus	TCGA;COSMIC	38.013	Down-regulation
CMGC_MAPK_p38_MAPK13_ST	P16949	STMN1	O15264	MAPK13	S38	P39S	39	Missense	proximal	1	no	52.410	26.859	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	38.013	Loss
CMGC_MAPK_p38_MAPK13_ST	Q13501	SQSTM1	O15264	MAPK13	S170	G173R	173	Missense	distal	3	no	44.023	44.314	EPSD	TCGA;ICGC;COSMIC	38.013	Up-regulation
CMGC_MAPK_p38_MAPK13_ST	Q13501	SQSTM1	O15264	MAPK13	S207	G204E	204	Missense	distal	-3	no	46.813	46.619	EPSD	TCGA;ICGC;COSMIC	38.013	Down-regulation
CMGC_MAPK_p38_MAPK13_ST	Q13501	SQSTM1	O15264	MAPK13	S207	G201D	201	Missense	distal	-6	no	46.813	46.860	EPSD	TCGA;ICGC;COSMIC	38.013	Up-regulation
CMGC_MAPK_p38_MAPK13_ST	Q13501	SQSTM1	O15264	MAPK13	S207	W206C	206	Missense	proximal	-1	no	46.813	46.488	EPSD	TCGA;ICGC;COSMIC	38.013	Down-regulation
CMGC_MAPK_p38_MAPK13_ST	Q13501	SQSTM1	O15264	MAPK13	S207	R209H	209	Missense	proximal	2	no	46.813	44.586	EPSD	TCGA;ICGC;COSMIC	38.013	Down-regulation
CMGC_MAPK_p38_MAPK13_ST	Q13501	SQSTM1	O15264	MAPK13	S207	R212C	212	Missense	distal	5	no	46.813	45.895	EPSD	TCGA	38.013	Down-regulation
CMGC_MAPK_p38_MAPK13_ST	Q13501	SQSTM1	O15264	MAPK13	S249	E242K	242	Missense	distal	-7	no	47.618	47.804	EPSD	TCGA;COSMIC	38.013	Up-regulation
CMGC_MAPK_p38_MAPK13_ST	Q13501	SQSTM1	O15264	MAPK13	S249	L248F	248	Missense	proximal	-1	no	47.618	47.566	EPSD	TCGA;COSMIC	38.013	Down-regulation
CMGC_MAPK_p38_MAPK13_ST	Q13501	SQSTM1	O15264	MAPK13	S249	V255I	255	Missense	distal	6	no	47.618	47.342	EPSD	TCGA;ICGC;COSMIC	38.013	Down-regulation
CMGC_MAPK_p38_MAPK13_ST	Q13501	SQSTM1	O15264	MAPK13	S249	L251M	251	Missense	proximal	2	no	47.618	46.902	EPSD	TCGA;ICGC;COSMIC	38.013	Down-regulation
CMGC_MAPK_p38_MAPK13_ST	Q13501	SQSTM1	O15264	MAPK13	T269	S276Y	276	Missense	distal	7	no	54.468	53.719	PhosphoSitePlus;EPSD	TCGA;ICGC	38.013	Down-regulation
CMGC_MAPK_p38_MAPK13_ST	Q13501	SQSTM1	O15264	MAPK13	T269	S266R	266	Missense	distal	-3	no	54.468	54.382	PhosphoSitePlus;EPSD	TCGA;ICGC	38.013	Down-regulation
CMGC_MAPK_p38_MAPK13_ST	Q13501	SQSTM1	O15264	MAPK13	S272	S277G	277	Missense	distal	5	no	54.137	53.775	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	38.013	Down-regulation
CMGC_MAPK_p38_MAPK13_ST	Q13501	SQSTM1	O15264	MAPK13	S272	S276Y	276	Missense	distal	4	no	54.137	53.114	EPSD;PhosphoSitePlus	TCGA;ICGC	38.013	Down-regulation
CMGC_MAPK_p38_MAPK13_ST	Q13501	SQSTM1	O15264	MAPK13	S272	S277I	277	Missense	distal	5	no	54.137	53.565	EPSD;PhosphoSitePlus	TCGA;ICGC	38.013	Down-regulation
CMGC_MAPK_p38_MAPK13_ST	Q13501	SQSTM1	O15264	MAPK13	S272	S266R	266	Missense	distal	-6	no	54.137	54.244	EPSD;PhosphoSitePlus	TCGA;ICGC	38.013	Up-regulation
CMGC_MAPK_p38_MAPK13_ST	Q13501	SQSTM1	O15264	MAPK13	S284	S284A	284	Missense	central	0	yes	43.411	0.000	EPSD	TCGA;ICGC;COSMIC	38.013	Loss
CMGC_MAPK_p38_MAPK13_ST	Q13501	SQSTM1	O15264	MAPK13	S284	S277G	277	Missense	distal	-7	no	43.411	44.069	EPSD	TCGA;ICGC;COSMIC	38.013	Up-regulation
CMGC_MAPK_p38_MAPK13_ST	Q13501	SQSTM1	O15264	MAPK13	S284	S277I	277	Missense	distal	-7	no	43.411	41.206	EPSD	TCGA;ICGC	38.013	Down-regulation
CMGC_MAPK_p38_MAPK13_ST	Q13501	SQSTM1	O15264	MAPK13	S355	P348L	348	Missense	distal	-7	no	40.187	40.350	EPSD	TCGA;COSMIC	38.013	Up-regulation
CMGC_MAPK_p38_MAPK13_ST	Q13501	SQSTM1	O15264	MAPK13	S366	L367V	367	Missense	proximal	1	no	34.095	38.258	EPSD	TCGA;COSMIC	38.013	Gain
CMGC_MAPK_p38_MAPK13_ST	P30281	CCND3	O15264	MAPK13	S133	I126M	126	Missense	distal	-7	no	43.271	44.217	EPSD	TCGA;COSMIC	38.013	Up-regulation
CMGC_MAPK_p38_MAPK13_ST	P30281	CCND3	O15264	MAPK13	S133	R135L	135	Missense	proximal	2	no	43.271	40.787	EPSD	TCGA;COSMIC	38.013	Down-regulation
CMGC_MAPK_p38_MAPK13_ST	P30281	CCND3	O15264	MAPK13	S259	P265T	265	Missense	distal	6	no	43.189	43.250	EPSD	TCGA;COSMIC	38.013	Up-regulation
CMGC_MAPK_p38_MAPK13_ST	P30281	CCND3	O15264	MAPK13	S259	S263C	263	Missense	distal	4	no	43.189	41.091	EPSD	TCGA;COSMIC	38.013	Down-regulation
CMGC_MAPK_p38_MAPK13_ST	P30281	CCND3	O15264	MAPK13	S259	Q260E	260	Missense	proximal	1	no	43.189	0.383	EPSD	TCGA;COSMIC	38.013	Loss
CMGC_MAPK_p38_MAPK13_ST	P30281	CCND3	O15264	MAPK13	S259	T261S	261	Missense	proximal	2	no	43.189	41.744	EPSD	TCGA;ICGC;COSMIC	38.013	Down-regulation
CMGC_MAPK_p38_MAPK13_ST	P30281	CCND3	O15264	MAPK13	S259	A266V	266	Missense	distal	7	no	43.189	43.723	EPSD	TCGA;ICGC;COSMIC;GDSC	38.013	Up-regulation
CMGC_MAPK_p38_MAPK13_ST	P30281	CCND3	O15264	MAPK13	S264	P265T	265	Missense	proximal	1	no	54.196	32.119	EPSD	TCGA;COSMIC	38.013	Loss
CMGC_MAPK_p38_MAPK13_ST	P30281	CCND3	O15264	MAPK13	S264	S263C	263	Missense	proximal	-1	no	54.196	52.869	EPSD	TCGA;COSMIC	38.013	Down-regulation
CMGC_MAPK_p38_MAPK13_ST	P30281	CCND3	O15264	MAPK13	S264	Q260E	260	Missense	distal	-4	no	54.196	53.386	EPSD	TCGA;COSMIC	38.013	Down-regulation
CMGC_MAPK_p38_MAPK13_ST	P30281	CCND3	O15264	MAPK13	S264	T261S	261	Missense	distal	-3	no	54.196	53.882	EPSD	TCGA;ICGC;COSMIC	38.013	Down-regulation
CMGC_MAPK_p38_MAPK13_ST	P30281	CCND3	O15264	MAPK13	S264	A266V	266	Missense	proximal	2	no	54.196	56.466	EPSD	TCGA;ICGC;COSMIC;GDSC	38.013	Up-regulation
CMGC_MAPK_p38_MAPK13_ST	P30281	CCND3	O15264	MAPK13	S275	P278R	278	Missense	distal	3	no	39.702	39.936	EPSD	TCGA;COSMIC	38.013	Up-regulation
CMGC_MAPK_p38_MAPK13_ST	P30281	CCND3	O15264	MAPK13	T283	P278R	278	Missense	distal	-5	no	47.606	47.322	PhosphoSitePlus	TCGA;COSMIC	38.013	Down-regulation
CMGC_MAPK_p38_MAPK13_ST	P30281	CCND3	O15264	MAPK13	T283	T283A	283	Missense	central	0	yes	47.606	0.000	PhosphoSitePlus	TCGA;ICGC;COSMIC;CCLE	38.013	Loss
CMGC_MAPK_p38_MAPK13_ST	P30281	CCND3	O15264	MAPK13	T283	V287I	287	Missense	distal	4	no	47.606	46.935	PhosphoSitePlus	TCGA;COSMIC	38.013	Down-regulation
STE_STE20_NinaC_MYO3A_ST	Q8NEV4	MYO3A	Q8NEV4	MYO3A	T178	R179L	179	Missense	proximal	1	no	9.069	9.017	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	3.030	Down-regulation
STE_STE20_NinaC_MYO3A_ST	Q8NEV4	MYO3A	Q8NEV4	MYO3A	T184	V186I	186	Missense	proximal	2	no	8.742	8.670	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	3.030	Down-regulation
STE_STE20_NinaC_MYO3A_ST	Q8NEV4	MYO3A	Q8NEV4	MYO3A	T184	R179L	179	Missense	distal	-5	no	8.742	8.633	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	3.030	Down-regulation
STE_STE20_NinaC_MYO3A_ST	Q8NEV4	MYO3A	Q8NEV4	MYO3A	T184	W191L	191	Missense	distal	7	no	8.742	8.675	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	3.030	Down-regulation
STE_STE20_NinaC_MYO3A_ST	Q8NEV4	MYO3A	Q8NEV4	MYO3A	T184	G187E	187	Missense	distal	3	no	8.742	8.757	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	3.030	Up-regulation
STE_STE20_NinaC_MYO3A_ST	Q8NEV4	MYO3A	Q8NEV4	MYO3A	S335	R331Q	331	Missense	distal	-4	no	3.416	3.421	EPSD	TCGA;ICGC;COSMIC	3.030	Up-regulation
STE_STE20_NinaC_MYO3A_ST	Q8NEV4	MYO3A	Q8NEV4	MYO3A	S335	N328S	328	Missense	distal	-7	no	3.416	3.347	EPSD	TCGA;ICGC;COSMIC	3.030	Down-regulation
STE_STE20_NinaC_MYO3A_ST	Q8NEV4	MYO3A	Q8NEV4	MYO3A	T908	A911D	911	Missense	distal	3	no	8.285	8.284	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	3.030	Down-regulation
STE_STE20_NinaC_MYO3A_ST	Q8NEV4	MYO3A	Q8NEV4	MYO3A	T908	A904E	904	Missense	distal	-4	no	8.285	8.313	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	3.030	Up-regulation
STE_STE20_NinaC_MYO3A_ST	Q8NEV4	MYO3A	Q8NEV4	MYO3A	T908	D907N	907	Missense	proximal	-1	no	8.285	8.299	EPSD;PhosphoSitePlus	TCGA;ICGC	3.030	Up-regulation
STE_STE20_NinaC_MYO3A_ST	Q8NEV4	MYO3A	Q8NEV4	MYO3A	T908	R913S	913	Missense	distal	5	no	8.285	8.305	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	3.030	Up-regulation
STE_STE20_NinaC_MYO3A_ST	Q8NEV4	MYO3A	Q8NEV4	MYO3A	T908	G906D	906	Missense	proximal	-2	no	8.285	8.206	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	3.030	Down-regulation
STE_STE20_NinaC_MYO3A_ST	Q8NEV4	MYO3A	Q8NEV4	MYO3A	T908	R913C	913	Missense	distal	5	no	8.285	8.293	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	3.030	Up-regulation
STE_STE20_NinaC_MYO3A_ST	Q8NEV4	MYO3A	Q8NEV4	MYO3A	T919	K922I	922	Missense	distal	3	no	9.799	9.766	PhosphoSitePlus;EPSD	TCGA;ICGC	3.030	Down-regulation
STE_STE20_NinaC_MYO3A_ST	Q8NEV4	MYO3A	Q8NEV4	MYO3A	T919	R913S	913	Missense	distal	-6	no	9.799	9.747	PhosphoSitePlus;EPSD	TCGA;ICGC;COSMIC	3.030	Down-regulation
STE_STE20_NinaC_MYO3A_ST	Q8NEV4	MYO3A	Q8NEV4	MYO3A	T919	M921I	921	Missense	proximal	2	no	9.799	9.508	PhosphoSitePlus;EPSD	TCGA;ICGC;COSMIC	3.030	Down-regulation
STE_STE20_NinaC_MYO3A_ST	Q8NEV4	MYO3A	Q8NEV4	MYO3A	T919	R913C	913	Missense	distal	-6	no	9.799	9.680	PhosphoSitePlus;EPSD	TCGA;ICGC;COSMIC	3.030	Down-regulation
STE_STE20_NinaC_MYO3A_ST	Q8NEV4	MYO3A	Q8NEV4	MYO3A	S1280	W1273R	1273	Missense	distal	-7	no	2.923	3.059	EPSD	TCGA;ICGC;COSMIC	3.030	Gain
TK_Src_SrcA_FYN_Y	Q12879	GRIN2A	P06241	FYN	Y698	Y700N	700	Missense	proximal	2	no	2.935	3.976	EPSD	TCGA;ICGC;COSMIC	3.469	Gain
TK_Src_SrcA_FYN_Y	Q12879	GRIN2A	P06241	FYN	Y698	P699S	699	Missense	proximal	1	no	2.935	4.113	EPSD	TCGA;ICGC;COSMIC	3.469	Gain
TK_Src_SrcA_FYN_Y	Q12879	GRIN2A	P06241	FYN	Y730	A733T	733	Missense	distal	3	no	3.858	4.377	EPSD	TCGA;ICGC;COSMIC	3.469	Up-regulation
TK_Src_SrcA_FYN_Y	Q12879	GRIN2A	P06241	FYN	Y730	G723W	723	Missense	distal	-7	no	3.858	2.729	EPSD	TCGA;ICGC;COSMIC	3.469	Loss
TK_Src_SrcA_FYN_Y	Q12879	GRIN2A	P06241	FYN	Y730	A727T	727	Missense	distal	-3	no	3.858	4.290	EPSD	TCGA;ICGC;COSMIC	3.469	Up-regulation
TK_Src_SrcA_FYN_Y	Q12879	GRIN2A	P06241	FYN	Y730	L735M	735	Missense	distal	5	no	3.858	4.095	EPSD	TCGA;ICGC;COSMIC	3.469	Up-regulation
TK_Src_SrcA_FYN_Y	Q12879	GRIN2A	P06241	FYN	Y730	D731N	731	Missense	proximal	1	no	3.858	2.987	EPSD	TCGA;ICGC;COSMIC	3.469	Loss
TK_Src_SrcA_FYN_Y	Q12879	GRIN2A	P06241	FYN	Y730	A732T	732	Missense	proximal	2	no	3.858	4.201	EPSD	TCGA;ICGC	3.469	Up-regulation
TK_Src_SrcA_FYN_Y	Q12879	GRIN2A	P06241	FYN	Y730	Y737H	737	Missense	distal	7	no	3.858	3.850	EPSD	TCGA;ICGC;COSMIC	3.469	Down-regulation
TK_Src_SrcA_FYN_Y	Q12879	GRIN2A	P06241	FYN	Y730	D726G	726	Missense	distal	-4	no	3.858	1.502	EPSD	TCGA;ICGC	3.469	Loss
TK_Src_SrcA_FYN_Y	Q12879	GRIN2A	P06241	FYN	Y943	G939R	939	Missense	distal	-4	no	3.404	4.213	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	3.469	Gain
TK_Src_SrcA_FYN_Y	Q12879	GRIN2A	P06241	FYN	Y943	G939V	939	Missense	distal	-4	no	3.404	3.742	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	3.469	Gain
TK_Src_SrcA_FYN_Y	Q12879	GRIN2A	P06241	FYN	Y943	N946S	946	Missense	distal	3	no	3.404	3.618	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	3.469	Gain
TK_Src_SrcA_FYN_Y	Q12879	GRIN2A	P06241	FYN	Y1118	R1114T	1114	Missense	distal	-4	no	3.737	4.223	PhosphoSitePlus;EPSD	TCGA;ICGC;COSMIC	3.469	Up-regulation
TK_Src_SrcA_FYN_Y	Q12879	GRIN2A	P06241	FYN	Y1118	D1121H	1121	Missense	distal	3	no	3.737	3.968	PhosphoSitePlus;EPSD	TCGA;ICGC;COSMIC	3.469	Up-regulation
TK_Src_SrcA_FYN_Y	Q12879	GRIN2A	P06241	FYN	Y1118	K1116T	1116	Missense	proximal	-2	no	3.737	4.668	PhosphoSitePlus;EPSD	TCGA;ICGC;COSMIC	3.469	Up-regulation
TK_Src_SrcA_FYN_Y	Q12879	GRIN2A	P06241	FYN	Y1118	P1113L	1113	Missense	distal	-5	no	3.737	3.301	PhosphoSitePlus;EPSD	TCGA;ICGC;COSMIC	3.469	Loss
TK_Src_SrcA_FYN_Y	Q12879	GRIN2A	P06241	FYN	Y1118	E1125K	1125	Missense	distal	7	no	3.737	3.683	PhosphoSitePlus;EPSD	TCGA;ICGC;COSMIC	3.469	Down-regulation
TK_Src_SrcA_FYN_Y	Q12879	GRIN2A	P06241	FYN	Y1246	G1243V	1243	Missense	distal	-3	no	4.092	2.777	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	3.469	Loss
TK_Src_SrcA_FYN_Y	Q12879	GRIN2A	P06241	FYN	Y1246	R1241Q	1241	Missense	distal	-5	no	4.092	4.239	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC;GDSC;CCLE	3.469	Up-regulation
TK_Src_SrcA_FYN_Y	Q12879	GRIN2A	P06241	FYN	Y1246	D1251Y	1251	Missense	distal	5	no	4.092	4.423	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	3.469	Up-regulation
TK_Src_SrcA_FYN_Y	Q12879	GRIN2A	P06241	FYN	Y1246	D1251N	1251	Missense	distal	5	no	4.092	4.315	EPSD;PhosphoSitePlus	TCGA;ICGC	3.469	Up-regulation
TK_Src_SrcA_FYN_Y	Q12879	GRIN2A	P06241	FYN	Y1246	N1244S	1244	Missense	proximal	-2	no	4.092	4.194	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	3.469	Up-regulation
TK_Src_SrcA_FYN_Y	Q12879	GRIN2A	P06241	FYN	Y1246	R1241W	1241	Missense	distal	-5	no	4.092	3.001	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	3.469	Loss
TK_Src_SrcA_FYN_Y	Q12879	GRIN2A	P06241	FYN	Y1267	A1261V	1261	Missense	distal	-6	no	7.932	7.994	EPSD;PhosphoSitePlus	TCGA	3.469	Up-regulation
TK_Src_SrcA_FYN_Y	Q12879	GRIN2A	P06241	FYN	Y1267	T1262S	1262	Missense	distal	-5	no	7.932	7.064	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	3.469	Down-regulation
TK_Src_SrcA_FYN_Y	Q12879	GRIN2A	P06241	FYN	Y1267	D1270H	1270	Missense	distal	3	no	7.932	8.162	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	3.469	Up-regulation
TK_Src_SrcA_FYN_Y	Q12879	GRIN2A	P06241	FYN	Y1292	R1288H	1288	Missense	distal	-4	no	5.278	5.004	EPSD	TCGA;ICGC;COSMIC	3.469	Down-regulation
TK_Src_SrcA_FYN_Y	Q12879	GRIN2A	P06241	FYN	Y1292	R1288C	1288	Missense	distal	-4	no	5.278	3.370	EPSD	TCGA;ICGC;COSMIC	3.469	Loss
TK_Src_SrcA_FYN_Y	Q12879	GRIN2A	P06241	FYN	Y1292	D1297N	1297	Missense	distal	5	no	5.278	5.502	EPSD	TCGA;ICGC;COSMIC	3.469	Up-regulation
TK_Src_SrcA_FYN_Y	Q12879	GRIN2A	P06241	FYN	Y1292	Y1292F	1292	Missense	central	0	yes	5.278	0.000	EPSD	TCGA;ICGC;COSMIC	3.469	Loss
TK_Src_SrcA_FYN_Y	Q12879	GRIN2A	P06241	FYN	Y1292	D1293Y	1293	Missense	proximal	1	no	5.278	4.457	EPSD	TCGA;ICGC;COSMIC	3.469	Down-regulation
TK_Src_SrcA_FYN_Y	Q12879	GRIN2A	P06241	FYN	Y1292	Q1289H	1289	Missense	distal	-3	no	5.278	5.153	EPSD	TCGA;ICGC;COSMIC	3.469	Down-regulation
TK_Src_SrcA_FYN_Y	Q12879	GRIN2A	P06241	FYN	Y1292	I1286S	1286	Missense	distal	-6	no	5.278	6.293	EPSD	TCGA;ICGC;COSMIC	3.469	Up-regulation
TK_Src_SrcA_FYN_Y	Q12879	GRIN2A	P06241	FYN	Y1325	R1318Q	1318	Missense	distal	-7	no	3.797	3.541	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	3.469	Down-regulation
TK_Src_SrcA_FYN_Y	Q12879	GRIN2A	P06241	FYN	Y1325	S1330N	1330	Missense	distal	5	no	3.797	4.016	EPSD;PhosphoSitePlus	TCGA;ICGC	3.469	Up-regulation
TK_Src_SrcA_FYN_Y	Q12879	GRIN2A	P06241	FYN	Y1325	G1322E	1322	Missense	distal	-3	no	3.797	3.972	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC;GDSC;CCLE	3.469	Up-regulation
TK_Src_SrcA_FYN_Y	Q12879	GRIN2A	P06241	FYN	Y1325	G1326D	1326	Missense	proximal	1	no	3.797	3.647	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	3.469	Down-regulation
TK_Src_SrcA_FYN_Y	Q96J02	ITCH	P06241	FYN	Y495	P494L	494	Missense	proximal	-1	no	3.984	3.680	EPSD	TCGA;ICGC;COSMIC	3.469	Down-regulation
TK_Src_SrcA_FYN_Y	Q96J02	ITCH	P06241	FYN	Y589	P582L	582	Missense	distal	-7	no	3.629	2.252	EPSD	TCGA;ICGC;COSMIC	3.469	Loss
TK_Src_SrcA_FYN_Y	Q96J02	ITCH	P06241	FYN	Y589	G586S	586	Missense	distal	-3	no	3.629	2.939	EPSD	TCGA;COSMIC	3.469	Loss
TK_Src_SrcA_FYN_Y	P30419	NMT1	P06241	FYN	Y41	S40I	40	Missense	proximal	-1	no	3.114	5.509	EPSD	TCGA;ICGC;COSMIC	3.469	Gain
TK_Src_SrcA_FYN_Y	P06127	CD5	P06241	FYN	Y51	M58I	58	Missense	distal	7	no	3.899	3.858	EPSD	TCGA;ICGC;COSMIC	3.469	Down-regulation
TK_Src_SrcA_FYN_Y	P06127	CD5	P06241	FYN	Y51	C44G	44	Missense	distal	-7	no	3.899	3.726	EPSD	TCGA;ICGC;COSMIC	3.469	Down-regulation
TK_Src_SrcA_FYN_Y	P06127	CD5	P06241	FYN	Y51	Q47K	47	Missense	distal	-4	no	3.899	3.097	EPSD	TCGA;ICGC;COSMIC	3.469	Loss
TK_Src_SrcA_FYN_Y	P06127	CD5	P06241	FYN	Y51	D54N	54	Missense	distal	3	no	3.899	4.599	EPSD	TCGA;ICGC;COSMIC;GDSC;CCLE	3.469	Up-regulation
TK_Src_SrcA_FYN_Y	P06127	CD5	P06241	FYN	Y51	E49D	49	Missense	proximal	-2	no	3.899	3.606	EPSD	TCGA;ICGC	3.469	Down-regulation
TK_Src_SrcA_FYN_Y	P06127	CD5	P06241	FYN	Y453	P456H	456	Missense	distal	3	no	6.493	5.219	PhosphoSitePlus;EPSD	TCGA;ICGC;COSMIC	3.469	Down-regulation
TK_Src_SrcA_FYN_Y	P06127	CD5	P06241	FYN	Y453	V449M	449	Missense	distal	-4	no	6.493	7.334	PhosphoSitePlus;EPSD	TCGA;ICGC;COSMIC	3.469	Up-regulation
TK_Src_SrcA_FYN_Y	P06127	CD5	P06241	FYN	Y453	E452K	452	Missense	proximal	-1	no	6.493	5.412	PhosphoSitePlus;EPSD	TCGA;ICGC;COSMIC	3.469	Down-regulation
TK_Src_SrcA_FYN_Y	P06127	CD5	P06241	FYN	Y453	S447P	447	Missense	distal	-6	no	6.493	5.740	PhosphoSitePlus;EPSD	TCGA;ICGC	3.469	Down-regulation
TK_Src_SrcA_FYN_Y	P06127	CD5	P06241	FYN	Y487	S485G	485	Missense	proximal	-2	no	3.992	4.277	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	3.469	Up-regulation
TK_Src_SrcA_FYN_Y	P06127	CD5	P06241	FYN	Y487	S483F	483	Missense	distal	-4	no	3.992	1.944	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	3.469	Loss
TK_Src_SrcA_FYN_Y	P16885	PLCG2	P06241	FYN	Y647	W646G	646	Missense	proximal	-1	no	1.758	3.608	EPSD	TCGA;ICGC;COSMIC	3.469	Gain
TK_Src_SrcA_FYN_Y	P16885	PLCG2	P06241	FYN	Y753	D754N	754	Missense	proximal	1	no	7.406	6.535	PhosphoSitePlus;EPSD	TCGA;ICGC;COSMIC	3.469	Down-regulation
TK_Src_SrcA_FYN_Y	P16885	PLCG2	P06241	FYN	Y753	D754A	754	Missense	proximal	1	no	7.406	5.984	PhosphoSitePlus;EPSD	TCGA;ICGC;COSMIC	3.469	Down-regulation
TK_Src_SrcA_FYN_Y	P16885	PLCG2	P06241	FYN	Y753	V755I	755	Missense	proximal	2	no	7.406	7.259	PhosphoSitePlus;EPSD	TCGA;ICGC;COSMIC	3.469	Down-regulation
TK_Src_SrcA_FYN_Y	P16885	PLCG2	P06241	FYN	Y759	D754N	754	Missense	distal	-5	no	3.649	3.266	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	3.469	Loss
TK_Src_SrcA_FYN_Y	P16885	PLCG2	P06241	FYN	Y759	D754A	754	Missense	distal	-5	no	3.649	2.820	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	3.469	Loss
TK_Src_SrcA_FYN_Y	P16885	PLCG2	P06241	FYN	Y759	S763N	763	Missense	distal	4	no	3.649	3.689	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	3.469	Up-regulation
TK_Src_SrcA_FYN_Y	P16885	PLCG2	P06241	FYN	Y759	V755I	755	Missense	distal	-4	no	3.649	3.433	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	3.469	Loss
TK_Src_SrcA_FYN_Y	P16885	PLCG2	P06241	FYN	Y1048	M1043V	1043	Missense	distal	-5	no	6.165	6.448	EPSD	TCGA;ICGC;COSMIC	3.469	Up-regulation
TK_Src_SrcA_FYN_Y	P16885	PLCG2	P06241	FYN	Y1048	E1046D	1046	Missense	proximal	-2	no	6.165	5.872	EPSD	TCGA;ICGC;COSMIC	3.469	Down-regulation
TK_Src_SrcA_FYN_Y	O75051	PLXNA2	P06241	FYN	Y1677	S1670N	1670	Missense	distal	-7	no	5.530	5.896	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	3.469	Up-regulation
TK_Src_SrcA_FYN_Y	O75051	PLXNA2	P06241	FYN	Y1677	R1680Q	1680	Missense	distal	3	no	5.530	5.099	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	3.469	Down-regulation
TK_Src_SrcA_FYN_Y	O75051	PLXNA2	P06241	FYN	Y1677	T1679I	1679	Missense	proximal	2	no	5.530	4.645	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	3.469	Down-regulation
TK_Src_SrcA_FYN_Y	Q03135	CAV1	P06241	FYN	Y14	G11A	11	Missense	distal	-3	no	5.566	5.149	PhosphoSitePlus	TCGA;ICGC;COSMIC	3.469	Down-regulation
TK_Src_SrcA_FYN_Y	Q03135	CAV1	P06241	FYN	Y14	E10K	10	Missense	distal	-4	no	5.566	4.796	PhosphoSitePlus	TCGA;ICGC;COSMIC	3.469	Down-regulation
TK_Src_SrcA_FYN_Y	Q03135	CAV1	P06241	FYN	Y14	E20K	20	Missense	distal	6	no	5.566	5.299	PhosphoSitePlus	TCGA;ICGC;COSMIC	3.469	Down-regulation
TK_Src_SrcA_FYN_Y	Q03135	CAV1	P06241	FYN	Y14	V7A	7	Missense	distal	-7	no	5.566	5.794	PhosphoSitePlus	TCGA;ICGC;COSMIC	3.469	Up-regulation
TK_Src_SrcA_FYN_Y	Q03135	CAV1	P06241	FYN	Y14	T15A	15	Missense	proximal	1	no	5.566	5.039	PhosphoSitePlus	TCGA;ICGC;COSMIC	3.469	Down-regulation
TK_Src_SrcA_FYN_Y	Q03135	CAV1	P06241	FYN	Y14	R19Q	19	Missense	distal	5	no	5.566	5.810	PhosphoSitePlus	TCGA;ICGC;COSMIC	3.469	Up-regulation
TK_Src_SrcA_FYN_Y	Q03135	CAV1	P06241	FYN	Y25	E20K	20	Missense	distal	-5	no	3.942	4.092	EPSD	TCGA;ICGC;COSMIC	3.469	Up-regulation
TK_Src_SrcA_FYN_Y	Q03135	CAV1	P06241	FYN	Y25	R19Q	19	Missense	distal	-6	no	3.942	3.562	EPSD	TCGA;ICGC;COSMIC	3.469	Down-regulation
TK_Src_SrcA_FYN_Y	P52757	CHN2	P06241	FYN	Y55	N51K	51	Missense	distal	-4	no	3.943	3.592	EPSD	TCGA;COSMIC	3.469	Down-regulation
TK_Src_SrcA_FYN_Y	P52757	CHN2	P06241	FYN	Y55	R58I	58	Missense	distal	3	no	3.943	4.062	EPSD	TCGA;COSMIC	3.469	Up-regulation
TK_Src_SrcA_FYN_Y	O14559	ARHGAP33	P06241	FYN	Y406	Y406C	406	Missense	central	0	yes	6.581	0.000	PhosphoSitePlus	TCGA;ICGC;COSMIC	3.469	Loss
TK_Src_SrcA_FYN_Y	P11274	BCR	P06241	FYN	Y455	S459L	459	Missense	distal	4	no	5.834	5.729	EPSD	TCGA;ICGC;COSMIC;GDSC;CCLE	3.469	Down-regulation
TK_Src_SrcA_FYN_Y	P11274	BCR	P06241	FYN	Y644	T651M	651	Missense	distal	7	no	5.060	5.055	EPSD	TCGA;ICGC;COSMIC	3.469	Down-regulation
TK_Src_SrcA_FYN_Y	P11274	BCR	P06241	FYN	Y644	N637K	637	Missense	distal	-7	no	5.060	4.364	EPSD	TCGA;ICGC;COSMIC	3.469	Down-regulation
TK_Src_SrcA_FYN_Y	P11274	BCR	P06241	FYN	Y644	D648N	648	Missense	distal	4	no	5.060	5.314	EPSD	TCGA;ICGC;COSMIC	3.469	Up-regulation
TK_Src_SrcA_FYN_Y	P11274	BCR	P06241	FYN	Y844	S843I	843	Missense	proximal	-1	no	1.607	4.002	EPSD	TCGA;ICGC;COSMIC	3.469	Gain
TK_Src_SrcA_FYN_Y	P11274	BCR	P06241	FYN	Y910	D904N	904	Missense	distal	-6	no	4.120	3.277	EPSD	TCGA;ICGC;COSMIC	3.469	Loss
TK_Src_SrcA_FYN_Y	P11274	BCR	P06241	FYN	Y910	V915A	915	Missense	distal	5	no	4.120	4.941	EPSD	TCGA;ICGC;COSMIC	3.469	Up-regulation
TK_Src_SrcA_FYN_Y	P11274	BCR	P06241	FYN	Y910	P907L	907	Missense	distal	-3	no	4.120	3.249	EPSD	TCGA;ICGC;COSMIC	3.469	Loss
TK_Src_SrcA_FYN_Y	P11274	BCR	P06241	FYN	Y1089	R1090H	1090	Missense	proximal	1	no	3.515	4.666	EPSD	TCGA;ICGC;COSMIC	3.469	Up-regulation
TK_Src_SrcA_FYN_Y	P11274	BCR	P06241	FYN	Y1089	V1091M	1091	Missense	proximal	2	no	3.515	3.474	EPSD	TCGA;ICGC;COSMIC	3.469	Down-regulation
TK_Src_SrcA_FYN_Y	P11274	BCR	P06241	FYN	Y1089	S1092F	1092	Missense	distal	3	no	3.515	3.440	EPSD	TCGA;ICGC;COSMIC	3.469	Loss
TK_Src_SrcA_FYN_Y	P11274	BCR	P06241	FYN	Y1089	A1095V	1095	Missense	distal	6	no	3.515	3.489	EPSD	TCGA;ICGC;COSMIC;GDSC;CCLE	3.469	Down-regulation
TK_Src_SrcA_FYN_Y	Q9NWQ8	PAG1	P06241	FYN	Y181	K188R	188	Missense	distal	7	no	6.193	6.223	EPSD	TCGA;ICGC;COSMIC;CCLE	3.469	Up-regulation
TK_Src_SrcA_FYN_Y	Q9NWQ8	PAG1	P06241	FYN	Y181	M175V	175	Missense	distal	-6	no	6.193	6.309	EPSD	TCGA;ICGC;COSMIC;GDSC;CCLE	3.469	Up-regulation
TK_Src_SrcA_FYN_Y	Q9NWQ8	PAG1	P06241	FYN	Y317	E310K	310	Missense	distal	-7	no	5.123	4.088	PhosphoSitePlus	TCGA;ICGC;COSMIC	3.469	Down-regulation
TK_Src_SrcA_FYN_Y	Q9NWQ8	PAG1	P06241	FYN	Y317	A315D	315	Missense	proximal	-2	no	5.123	4.417	PhosphoSitePlus	TCGA;ICGC	3.469	Down-regulation
TK_Src_SrcA_FYN_Y	P07766	CD3E	P06241	FYN	Y188	E189Q	189	Missense	proximal	1	no	5.331	4.677	PhosphoSitePlus;EPSD	TCGA;COSMIC	3.469	Down-regulation
TK_Src_SrcA_FYN_Y	P07766	CD3E	P06241	FYN	Y188	D187G	187	Missense	proximal	-1	no	5.331	5.356	PhosphoSitePlus;EPSD	TCGA;COSMIC	3.469	Up-regulation
TK_Src_SrcA_FYN_Y	P07766	CD3E	P06241	FYN	Y188	P181T	181	Missense	distal	-7	no	5.331	4.750	PhosphoSitePlus;EPSD	TCGA;COSMIC	3.469	Down-regulation
TK_Src_SrcA_FYN_Y	P07766	CD3E	P06241	FYN	Y188	P181L	181	Missense	distal	-7	no	5.331	3.955	PhosphoSitePlus;EPSD	TCGA;COSMIC	3.469	Down-regulation
TK_Src_SrcA_FYN_Y	P07766	CD3E	P06241	FYN	Y188	P190L	190	Missense	proximal	2	no	5.331	5.109	PhosphoSitePlus;EPSD	TCGA;COSMIC	3.469	Down-regulation
TK_Src_SrcA_FYN_Y	Q86WV1	SKAP1	P06241	FYN	Y219	T216S	216	Missense	distal	-3	no	4.627	3.923	EPSD	TCGA;ICGC;COSMIC	3.469	Down-regulation
TK_Src_SrcA_FYN_Y	Q86WV1	SKAP1	P06241	FYN	Y232	D239N	239	Missense	distal	7	no	7.822	7.840	PhosphoSitePlus;EPSD	TCGA;ICGC;COSMIC	3.469	Up-regulation
TK_Src_SrcA_FYN_Y	Q86WV1	SKAP1	P06241	FYN	Y271	E272K	272	Missense	proximal	1	no	7.181	5.770	EPSD	TCGA;ICGC;COSMIC	3.469	Down-regulation
TK_Src_SrcA_FYN_Y	Q86WV1	SKAP1	P06241	FYN	Y271	E266D	266	Missense	distal	-5	no	7.181	7.258	EPSD	TCGA;ICGC;COSMIC	3.469	Up-regulation
TK_Src_SrcA_FYN_Y	P14923	JUP	P06241	FYN	Y550	Q548L	548	Missense	proximal	-2	no	3.818	3.496	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	3.469	Down-regulation
TK_Src_SrcA_FYN_Y	P14923	JUP	P06241	FYN	Y550	T551M	551	Missense	proximal	1	no	3.818	2.261	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC;GDSC	3.469	Loss
TK_Src_SrcA_FYN_Y	P14923	JUP	P06241	FYN	Y550	G545C	545	Missense	distal	-5	no	3.818	3.650	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	3.469	Down-regulation
TK_Src_SrcA_FYN_Y	P14923	JUP	P06241	FYN	Y701	R702H	702	Missense	proximal	1	no	2.760	3.912	EPSD	TCGA;ICGC;COSMIC	3.469	Gain
TK_Src_SrcA_FYN_Y	Q14194	CRMP1	P06241	FYN	Y504	P510S	510	Missense	distal	6	no	6.638	6.600	PhosphoSitePlus	TCGA	3.469	Down-regulation
TK_Src_SrcA_FYN_Y	Q16236	NFE2L2	P06241	FYN	Y576	R569H	569	Missense	distal	-7	no	5.519	4.064	PhosphoSitePlus	TCGA;COSMIC	3.469	Down-regulation
TK_Src_SrcA_FYN_Y	Q16236	NFE2L2	P06241	FYN	Y576	P575L	575	Missense	proximal	-1	no	5.519	5.215	PhosphoSitePlus	TCGA;COSMIC	3.469	Down-regulation
TK_Src_SrcA_FYN_Y	Q16236	NFE2L2	P06241	FYN	Y576	D570N	570	Missense	distal	-6	no	5.519	4.677	PhosphoSitePlus	TCGA;COSMIC	3.469	Down-regulation
TK_Src_SrcA_FYN_Y	Q16236	NFE2L2	P06241	FYN	Y576	P575S	575	Missense	proximal	-1	no	5.519	3.848	PhosphoSitePlus	TCGA;COSMIC	3.469	Down-regulation
TK_Src_SrcA_FYN_Y	Q14524	SCN5A	P06241	FYN	Y1494	K1492N	1492	Missense	proximal	-2	no	3.435	4.133	PhosphoSitePlus;EPSD	TCGA;COSMIC	3.469	Gain
TK_Src_SrcA_FYN_Y	Q14524	SCN5A	P06241	FYN	Y1495	K1492N	1492	Missense	distal	-3	no	6.999	7.678	EPSD;PhosphoSitePlus	TCGA;COSMIC	3.469	Up-regulation
TK_Src_SrcA_FYN_Y	Q14524	SCN5A	P06241	FYN	Y1495	K1500T	1500	Missense	distal	5	no	6.999	6.457	EPSD;PhosphoSitePlus	TCGA;COSMIC	3.469	Down-regulation
TK_Src_SrcA_FYN_Y	Q9UIW2	PLXNA1	P06241	FYN	Y159	S162N	162	Missense	distal	3	no	3.743	3.529	EPSD	TCGA;COSMIC	3.469	Down-regulation
TK_Src_SrcA_FYN_Y	Q9UIW2	PLXNA1	P06241	FYN	Y1486	L1493F	1493	Missense	distal	7	no	3.750	3.758	EPSD	TCGA;COSMIC	3.469	Up-regulation
TK_Src_SrcA_FYN_Y	Q9UIW2	PLXNA1	P06241	FYN	Y1486	S1487F	1487	Missense	proximal	1	no	3.750	1.958	EPSD	TCGA;COSMIC	3.469	Loss
TK_Src_SrcA_FYN_Y	Q9UIW2	PLXNA1	P06241	FYN	Y1486	A1479T	1479	Missense	distal	-7	no	3.750	3.803	EPSD	TCGA;ICGC	3.469	Up-regulation
TK_Src_SrcA_FYN_Y	Q9UIW2	PLXNA1	P06241	FYN	Y1486	R1485C	1485	Missense	proximal	-1	no	3.750	3.321	EPSD	TCGA;ICGC	3.469	Loss
TK_Src_SrcA_FYN_Y	Q9UIW2	PLXNA1	P06241	FYN	Y1608	K1603E	1603	Missense	distal	-5	no	4.852	4.702	EPSD;PhosphoSitePlus	TCGA;COSMIC	3.469	Down-regulation
TK_Src_SrcA_FYN_Y	Q9UIW2	PLXNA1	P06241	FYN	Y1608	S1613P	1613	Missense	distal	5	no	4.852	4.780	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	3.469	Down-regulation
TK_Src_SrcA_FYN_Y	Q9UIW2	PLXNA1	P06241	FYN	Y1679	R1682L	1682	Missense	distal	3	no	5.272	5.244	PhosphoSitePlus;EPSD	TCGA;COSMIC	3.469	Down-regulation
TK_Src_SrcA_FYN_Y	Q9UIW2	PLXNA1	P06241	FYN	Y1679	R1682W	1682	Missense	distal	3	no	5.272	4.127	PhosphoSitePlus;EPSD	TCGA;COSMIC	3.469	Down-regulation
TK_Src_SrcA_FYN_Y	Q9UIW2	PLXNA1	P06241	FYN	Y1679	K1673N	1673	Missense	distal	-6	no	5.272	4.712	PhosphoSitePlus;EPSD	TCGA;COSMIC	3.469	Down-regulation
TK_Src_SrcA_FYN_Y	P11137	MAP2	P06241	FYN	Y50	A45T	45	Missense	distal	-5	no	6.379	7.295	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	3.469	Up-regulation
TK_Src_SrcA_FYN_Y	P11137	MAP2	P06241	FYN	Y50	R51M	51	Missense	proximal	1	no	6.379	5.542	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	3.469	Down-regulation
TK_Src_SrcA_FYN_Y	P11137	MAP2	P06241	FYN	Y67	E60K	60	Missense	distal	-7	no	5.132	4.096	PhosphoSitePlus;EPSD	TCGA;ICGC;COSMIC	3.469	Down-regulation
TK_Src_SrcA_FYN_Y	P11137	MAP2	P06241	FYN	Y67	E72D	72	Missense	distal	5	no	5.132	4.971	PhosphoSitePlus;EPSD	TCGA;ICGC;COSMIC	3.469	Down-regulation
TK_Src_SrcA_FYN_Y	P11137	MAP2	P06241	FYN	Y563	Y563C	563	Missense	central	0	yes	4.607	0.000	EPSD	TCGA;COSMIC	3.469	Loss
TK_Src_SrcA_FYN_Y	P11137	MAP2	P06241	FYN	Y563	D559H	559	Missense	distal	-4	no	4.607	2.785	EPSD	TCGA;COSMIC	3.469	Loss
TK_Src_SrcA_FYN_Y	P11137	MAP2	P06241	FYN	Y563	K566E	566	Missense	distal	3	no	4.607	5.115	EPSD	TCGA;COSMIC	3.469	Up-regulation
TK_Src_SrcA_FYN_Y	P11137	MAP2	P06241	FYN	Y592	E587Q	587	Missense	distal	-5	no	3.930	3.762	EPSD	TCGA;COSMIC	3.469	Down-regulation
TK_Src_SrcA_FYN_Y	P11137	MAP2	P06241	FYN	Y592	G589A	589	Missense	distal	-3	no	3.930	3.513	EPSD	TCGA;COSMIC	3.469	Down-regulation
TK_Src_SrcA_FYN_Y	P11137	MAP2	P06241	FYN	Y592	E587D	587	Missense	distal	-5	no	3.930	4.007	EPSD	TCGA;COSMIC	3.469	Up-regulation
TK_Src_SrcA_FYN_Y	P11137	MAP2	P06241	FYN	Y745	D744N	744	Missense	proximal	-1	no	2.799	3.811	EPSD	TCGA;COSMIC	3.469	Gain
TK_Src_SrcA_FYN_Y	P11137	MAP2	P06241	FYN	Y745	A748V	748	Missense	distal	3	no	2.799	4.230	EPSD	TCGA;COSMIC	3.469	Gain
TK_Src_SrcA_FYN_Y	P11137	MAP2	P06241	FYN	Y1131	E1129G	1129	Missense	proximal	-2	no	4.486	4.941	EPSD	TCGA	3.469	Up-regulation
TK_Src_SrcA_FYN_Y	P51812	RPS6KA3	P06241	FYN	Y144	I146T	146	Missense	proximal	2	no	3.444	4.328	EPSD	TCGA;COSMIC	3.469	Gain
TK_Src_SrcA_FYN_Y	P51812	RPS6KA3	P06241	FYN	Y356	F355L	355	Missense	proximal	-1	no	2.616	3.735	EPSD	TCGA;ICGC;COSMIC	3.469	Gain
TK_Src_SrcA_FYN_Y	P51812	RPS6KA3	P06241	FYN	Y529	V527I	527	Missense	proximal	-2	no	4.478	4.027	PhosphoSitePlus;EPSD	TCGA;ICGC;COSMIC	3.469	Down-regulation
TK_Src_SrcA_FYN_Y	P51812	RPS6KA3	P06241	FYN	Y529	A532V	532	Missense	distal	3	no	4.478	5.909	PhosphoSitePlus;EPSD	TCGA;ICGC;COSMIC	3.469	Up-regulation
TK_Src_SrcA_FYN_Y	P51812	RPS6KA3	P06241	FYN	Y529	A532T	532	Missense	distal	3	no	4.478	4.997	PhosphoSitePlus;EPSD	TCGA;ICGC;COSMIC	3.469	Up-regulation
TK_Src_SrcA_FYN_Y	P51812	RPS6KA3	P06241	FYN	Y707	R712C	712	Missense	distal	5	no	7.301	6.792	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	3.469	Down-regulation
TK_Src_SrcA_FYN_Y	P51812	RPS6KA3	P06241	FYN	Y707	A702V	702	Missense	distal	-5	no	7.301	7.788	EPSD;PhosphoSitePlus	TCGA	3.469	Up-regulation
TK_Src_SrcA_FYN_Y	P51812	RPS6KA3	P06241	FYN	Y707	R712H	712	Missense	distal	5	no	7.301	6.817	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC;GDSC;CCLE	3.469	Down-regulation
TK_Src_SrcA_FYN_Y	O43490	PROM1	P06241	FYN	Y214	L216V	216	Missense	proximal	2	no	4.698	4.783	EPSD	TCGA;COSMIC	3.469	Up-regulation
TK_Src_SrcA_FYN_Y	O43490	PROM1	P06241	FYN	Y214	Q211L	211	Missense	distal	-3	no	4.698	3.312	EPSD	TCGA;COSMIC	3.469	Loss
TK_Src_SrcA_FYN_Y	O43490	PROM1	P06241	FYN	Y214	E207K	207	Missense	distal	-7	no	4.698	3.662	EPSD	TCGA;COSMIC	3.469	Down-regulation
TK_Src_SrcA_FYN_Y	O43490	PROM1	P06241	FYN	Y828	R821Q	821	Missense	distal	-7	no	7.475	7.219	EPSD;PhosphoSitePlus	TCGA;COSMIC	3.469	Down-regulation
TK_Src_SrcA_FYN_Y	P04626	ERBB2	P06241	FYN	Y1005	R1006C	1006	Missense	proximal	1	no	3.867	2.425	EPSD	TCGA;COSMIC	3.469	Loss
TK_Src_SrcA_FYN_Y	Q14247	CTTN	P06241	FYN	Y199	D202N	202	Missense	distal	3	no	2.836	3.536	EPSD	TCGA;ICGC	3.469	Gain
TK_Src_SrcA_FYN_Y	O75886	STAM2	P06241	FYN	Y291	I292V	292	Missense	proximal	1	no	8.221	8.316	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	3.469	Up-regulation
TK_Src_SrcA_FYN_Y	O75886	STAM2	P06241	FYN	Y291	K296N	296	Missense	distal	5	no	8.221	8.017	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	3.469	Down-regulation
TK_Src_SrcA_FYN_Y	O75886	STAM2	P06241	FYN	Y291	V290I	290	Missense	proximal	-1	no	8.221	7.554	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	3.469	Down-regulation
TK_Src_SrcA_FYN_Y	O75886	STAM2	P06241	FYN	Y371	V370L	370	Missense	proximal	-1	no	8.745	7.050	PhosphoSitePlus;EPSD	TCGA;ICGC;COSMIC	3.469	Down-regulation
TK_Src_SrcA_FYN_Y	O75886	STAM2	P06241	FYN	Y371	V370M	370	Missense	proximal	-1	no	8.745	7.308	PhosphoSitePlus;EPSD	TCGA;ICGC;COSMIC	3.469	Down-regulation
TK_Src_SrcA_FYN_Y	O75886	STAM2	P06241	FYN	Y371	L364S	364	Missense	distal	-7	no	8.745	9.257	PhosphoSitePlus;EPSD	TCGA;ICGC;COSMIC	3.469	Up-regulation
TK_Src_SrcA_FYN_Y	O75886	STAM2	P06241	FYN	Y374	V370L	370	Missense	distal	-4	no	4.897	4.639	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	3.469	Down-regulation
TK_Src_SrcA_FYN_Y	O75886	STAM2	P06241	FYN	Y374	V370M	370	Missense	distal	-4	no	4.897	5.738	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	3.469	Up-regulation
TK_Src_SrcA_FYN_Y	P05067	APP	P06241	FYN	Y757	M752I	752	Missense	distal	-5	no	4.433	3.830	PhosphoSitePlus	TCGA;COSMIC	3.469	Down-regulation
TK_Src_SrcA_FYN_Y	P05067	APP	P06241	FYN	Y757	F764L	764	Missense	distal	7	no	4.433	4.425	PhosphoSitePlus	TCGA;COSMIC	3.469	Down-regulation
TK_Src_SrcA_FYN_Y	O43294	TGFB1I1	P06241	FYN	Y60	T62M	62	Missense	proximal	2	no	6.344	5.566	PhosphoSitePlus	TCGA;COSMIC;GDSC;CCLE	3.469	Down-regulation
TK_Src_SrcA_FYN_Y	O43294	TGFB1I1	P06241	FYN	Y60	D55N	55	Missense	distal	-5	no	6.344	5.961	PhosphoSitePlus	TCGA;COSMIC	3.469	Down-regulation
TK_Src_SrcA_FYN_Y	O43294	TGFB1I1	P06241	FYN	Y60	T62K	62	Missense	proximal	2	no	6.344	6.009	PhosphoSitePlus	TCGA;COSMIC	3.469	Down-regulation
TK_Src_SrcA_FYN_Y	O43294	TGFB1I1	P06241	FYN	Y60	R67W	67	Missense	distal	7	no	6.344	6.248	PhosphoSitePlus	TCGA;COSMIC	3.469	Down-regulation
TK_Src_SrcA_FYN_Y	P06241	FYN	P06241	FYN	Y28	R29G	29	Missense	proximal	1	no	4.699	6.463	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	3.469	Up-regulation
TK_Src_SrcA_FYN_Y	P06241	FYN	P06241	FYN	Y28	Y30C	30	Missense	proximal	2	no	4.699	3.272	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC;GDSC;CCLE	3.469	Loss
TK_Src_SrcA_FYN_Y	P06241	FYN	P06241	FYN	Y39	P40S	40	Missense	proximal	1	no	3.239	4.417	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	3.469	Gain
TK_Src_SrcA_FYN_Y	P06241	FYN	P06241	FYN	Y185	R190C	190	Missense	distal	5	no	6.198	5.689	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	3.469	Down-regulation
TK_Src_SrcA_FYN_Y	P06241	FYN	P06241	FYN	Y185	S188Y	188	Missense	distal	3	no	6.198	5.379	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	3.469	Down-regulation
TK_Src_SrcA_FYN_Y	P06241	FYN	P06241	FYN	Y213	R206C	206	Missense	distal	-7	no	8.730	7.902	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC;GDSC;CCLE	3.469	Down-regulation
TK_Src_SrcA_FYN_Y	P06241	FYN	P06241	FYN	Y213	R218W	218	Missense	distal	5	no	8.730	7.870	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	3.469	Down-regulation
TK_Src_SrcA_FYN_Y	P06241	FYN	P06241	FYN	Y213	R206H	206	Missense	distal	-7	no	8.730	7.274	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	3.469	Down-regulation
TK_Src_SrcA_FYN_Y	P06241	FYN	P06241	FYN	Y339	P337S	337	Missense	proximal	-2	no	3.788	3.894	EPSD	TCGA;COSMIC	3.469	Up-regulation
TK_Src_SrcA_FYN_Y	P06241	FYN	P06241	FYN	Y420	A426T	426	Missense	distal	6	no	8.640	8.558	EPSD;PhosphoSitePlus	TCGA;COSMIC	3.469	Down-regulation
TK_Src_SrcA_FYN_Y	Q13291	SLAMF1	P06241	FYN	Y281	Q283E	283	Missense	proximal	2	no	4.588	5.554	PhosphoSitePlus;EPSD	TCGA	3.469	Up-regulation
TK_Src_SrcA_FYN_Y	Q13291	SLAMF1	P06241	FYN	Y281	T279M	279	Missense	proximal	-2	no	4.588	3.874	PhosphoSitePlus;EPSD	TCGA;ICGC;COSMIC	3.469	Down-regulation
TK_Src_SrcA_FYN_Y	Q13291	SLAMF1	P06241	FYN	Y281	E274K	274	Missense	distal	-7	no	4.588	3.553	PhosphoSitePlus;EPSD	TCGA;ICGC;COSMIC	3.469	Down-regulation
TK_Src_SrcA_FYN_Y	Q13291	SLAMF1	P06241	FYN	Y281	E274G	274	Missense	distal	-7	no	4.588	3.555	PhosphoSitePlus;EPSD	TCGA;ICGC;COSMIC;GDSC;CCLE	3.469	Down-regulation
TK_Src_SrcA_FYN_Y	Q13291	SLAMF1	P06241	FYN	Y281	L278F	278	Missense	distal	-3	no	4.588	3.548	PhosphoSitePlus;EPSD	TCGA;ICGC	3.469	Down-regulation
TK_Src_SrcA_FYN_Y	Q13291	SLAMF1	P06241	FYN	Y281	K286Q	286	Missense	distal	5	no	4.588	4.584	PhosphoSitePlus;EPSD	TCGA;ICGC;COSMIC	3.469	Down-regulation
TK_Src_SrcA_FYN_Y	Q99490	AGAP2	P06241	FYN	Y1038	Q1040R	1040	Missense	proximal	2	no	4.198	3.003	EPSD	TCGA;ICGC;COSMIC	3.469	Loss
TK_Src_SrcA_FYN_Y	P54646	PRKAA2	P06241	FYN	Y179	G175R	175	Missense	distal	-4	no	2.687	3.496	EPSD	TCGA;ICGC;COSMIC	3.469	Gain
TK_Src_SrcA_FYN_Y	P52209	PGD	P06241	FYN	Y106	R112W	112	Missense	distal	6	no	3.563	4.095	EPSD	TCGA;ICGC;CCLE	3.469	Up-regulation
TK_Src_SrcA_FYN_Y	Q16539	MAPK14	P06241	FYN	Y140	L135I	135	Missense	distal	-5	no	3.750	3.582	EPSD	TCGA;ICGC;COSMIC	3.469	Down-regulation
TK_Src_SrcA_FYN_Y	Q16539	MAPK14	P06241	FYN	Y140	A144T	144	Missense	distal	4	no	3.750	3.809	EPSD	TCGA;COSMIC	3.469	Up-regulation
TK_Src_SrcA_FYN_Y	Q16539	MAPK14	P06241	FYN	Y323	D324A	324	Missense	proximal	1	no	4.394	2.973	PhosphoSitePlus	TCGA;COSMIC	3.469	Loss
TK_Src_SrcA_FYN_Y	Q8TDQ1	CD300LF	P06241	FYN	Y263	G267S	267	Missense	distal	4	no	3.519	3.694	PhosphoSitePlus;EPSD	TCGA;ICGC;COSMIC	3.469	Up-regulation
TK_Src_SrcA_FYN_Y	O75955	FLOT1	P06241	FYN	Y160	H162Y	162	Missense	proximal	2	no	4.054	4.083	PhosphoSitePlus	TCGA;ICGC;COSMIC	3.469	Up-regulation
TK_Src_SrcA_FYN_Y	O75955	FLOT1	P06241	FYN	Y223	E217K	217	Missense	distal	-6	no	4.117	4.452	EPSD	TCGA;ICGC;COSMIC	3.469	Up-regulation
TK_Src_SrcA_FYN_Y	O75955	FLOT1	P06241	FYN	Y223	A221V	221	Missense	proximal	-2	no	4.117	3.443	EPSD	TCGA;ICGC;COSMIC	3.469	Loss
TK_Src_SrcA_FYN_Y	Q15858	SCN9A	P06241	FYN	Y1481	M1474I	1474	Missense	distal	-7	no	4.099	2.720	EPSD;PhosphoSitePlus	TCGA;COSMIC	3.469	Loss
TK_Src_SrcA_FYN_Y	Q15858	SCN9A	P06241	FYN	Y1481	M1474T	1474	Missense	distal	-7	no	4.099	4.210	EPSD;PhosphoSitePlus	TCGA;COSMIC	3.469	Up-regulation
TK_Src_SrcA_FYN_Y	P22681	CBL	P06241	FYN	Y552	P546L	546	Missense	distal	-6	no	3.362	3.559	EPSD	TCGA;ICGC;COSMIC	3.469	Gain
TK_Src_SrcA_FYN_Y	P22681	CBL	P06241	FYN	Y731	T730M	730	Missense	proximal	-1	no	3.399	3.780	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	3.469	Gain
TK_Src_SrcA_FYN_Y	P22681	CBL	P06241	FYN	Y774	D772Y	772	Missense	proximal	-2	no	6.078	6.280	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	3.469	Up-regulation
TK_Src_SrcA_FYN_Y	P22681	CBL	P06241	FYN	Y774	D775V	775	Missense	proximal	1	no	6.078	4.712	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	3.469	Down-regulation
TK_Src_SrcA_FYN_Y	Q12913	PTPRJ	P06241	FYN	Y587	Y587H	587	Missense	central	0	yes	5.344	0.000	EPSD	TCGA;ICGC;COSMIC	3.469	Loss
TK_Src_SrcA_FYN_Y	Q12913	PTPRJ	P06241	FYN	Y1071	R1070H	1070	Missense	proximal	-1	no	2.825	5.123	EPSD	TCGA;ICGC;COSMIC	3.469	Gain
TK_Src_SrcA_FYN_Y	Q12913	PTPRJ	P06241	FYN	Y1094	A1097G	1097	Missense	distal	3	no	3.004	3.729	EPSD	TCGA;ICGC;COSMIC	3.469	Gain
TK_Src_SrcA_FYN_Y	Q12913	PTPRJ	P06241	FYN	Y1268	V1265L	1265	Missense	distal	-3	no	6.974	6.170	EPSD	TCGA;ICGC;COSMIC	3.469	Down-regulation
TK_Src_SrcA_FYN_Y	Q12913	PTPRJ	P06241	FYN	Y1268	Y1272H	1272	Missense	distal	4	no	6.974	7.027	EPSD	TCGA;ICGC;COSMIC;GDSC;CCLE	3.469	Up-regulation
TK_Src_SrcA_FYN_Y	Q12913	PTPRJ	P06241	FYN	Y1268	R1275Q	1275	Missense	distal	7	no	6.974	6.950	EPSD	TCGA;ICGC;COSMIC	3.469	Down-regulation
TK_Src_SrcA_FYN_Y	Q12913	PTPRJ	P06241	FYN	Y1311	Q1312R	1312	Missense	proximal	1	no	7.089	6.975	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	3.469	Down-regulation
TK_Src_SrcA_FYN_Y	Q12913	PTPRJ	P06241	FYN	Y1320	Y1320F	1320	Missense	central	0	yes	4.307	0.000	PhosphoSitePlus;EPSD	TCGA;ICGC;COSMIC	3.469	Loss
TK_Src_SrcA_FYN_Y	Q12913	PTPRJ	P06241	FYN	Y1320	A1324V	1324	Missense	distal	4	no	4.307	4.258	PhosphoSitePlus;EPSD	TCGA;ICGC;COSMIC	3.469	Down-regulation
TK_Src_SrcA_FYN_Y	Q14254	FLOT2	P06241	FYN	Y158	S151N	151	Missense	distal	-7	no	4.732	5.098	EPSD	TCGA;ICGC	3.469	Up-regulation
TK_Src_SrcA_FYN_Y	Q96LC7	SIGLEC10	P06241	FYN	Y57	A56V	56	Missense	proximal	-1	no	1.021	3.698	EPSD	TCGA;ICGC	3.469	Gain
TK_Src_SrcA_FYN_Y	Q96LC7	SIGLEC10	P06241	FYN	Y597	N599D	599	Missense	proximal	2	no	4.679	4.562	EPSD	TCGA;ICGC;COSMIC	3.469	Down-regulation
TK_Src_SrcA_FYN_Y	Q96LC7	SIGLEC10	P06241	FYN	Y667	E663Q	663	Missense	distal	-4	no	5.227	5.259	PhosphoSitePlus	TCGA;COSMIC	3.469	Up-regulation
TK_Src_SrcA_FYN_Y	Q96LC7	SIGLEC10	P06241	FYN	Y667	E660K	660	Missense	distal	-7	no	5.227	4.192	PhosphoSitePlus	TCGA;COSMIC	3.469	Down-regulation
TK_Src_SrcA_FYN_Y	Q96LC7	SIGLEC10	P06241	FYN	Y667	Q662L	662	Missense	distal	-5	no	5.227	4.411	PhosphoSitePlus	TCGA;COSMIC	3.469	Down-regulation
TK_Src_SrcA_FYN_Y	Q96LC7	SIGLEC10	P06241	FYN	Y691	F696L	696	Missense	distal	5	no	4.595	4.365	EPSD	TCGA;ICGC	3.469	Down-regulation
TK_Src_SrcA_FYN_Y	P49023	PXN	P06241	FYN	Y118	Q124H	124	Missense	distal	6	no	6.888	6.957	PhosphoSitePlus	TCGA;COSMIC	3.469	Up-regulation
TK_Src_SrcA_FYN_Y	P49023	PXN	P06241	FYN	Y181	S188N	188	Missense	distal	7	no	4.438	4.457	EPSD	TCGA	3.469	Up-regulation
TK_Src_SrcA_FYN_Y	P37840	SNCA	P06241	FYN	Y39	E35K	35	Missense	distal	-4	no	5.433	4.662	EPSD	TCGA;ICGC;COSMIC	3.469	Down-regulation
TK_Src_SrcA_FYN_Y	P37840	SNCA	P06241	FYN	Y125	P120S	120	Missense	distal	-5	no	5.616	5.460	PhosphoSitePlus	TCGA;ICGC;COSMIC	3.469	Down-regulation
TK_Src_SrcA_FYN_Y	P37840	SNCA	P06241	FYN	Y125	S129F	129	Missense	distal	4	no	5.616	5.454	PhosphoSitePlus	TCGA;ICGC;COSMIC	3.469	Down-regulation
TK_Src_SrcA_FYN_Y	P37840	SNCA	P06241	FYN	Y136	E137K	137	Missense	proximal	1	no	3.961	2.550	EPSD	TCGA;ICGC;COSMIC	3.469	Loss
TK_Src_SrcA_FYN_Y	P37840	SNCA	P06241	FYN	Y136	D135Y	135	Missense	proximal	-1	no	3.961	4.549	EPSD	TCGA;ICGC;COSMIC	3.469	Up-regulation
TK_Src_SrcA_FYN_Y	P37840	SNCA	P06241	FYN	Y136	S129F	129	Missense	distal	-7	no	3.961	2.436	EPSD	TCGA;ICGC;COSMIC	3.469	Loss
TK_Src_SrcA_FYN_Y	Q9NPH5	NOX4	P06241	FYN	Y566	G567V	567	Missense	proximal	1	no	5.844	4.328	PhosphoSitePlus	TCGA;COSMIC	3.469	Down-regulation
TK_Src_SrcA_FYN_Y	Q9NPH5	NOX4	P06241	FYN	Y566	R569I	569	Missense	distal	3	no	5.844	5.963	PhosphoSitePlus	TCGA;COSMIC	3.469	Up-regulation
TK_Src_SrcA_FYN_Y	Q9NPH5	NOX4	P06241	FYN	Y566	R569K	569	Missense	distal	3	no	5.844	4.839	PhosphoSitePlus	TCGA	3.469	Down-regulation
TK_Src_SrcA_FYN_Y	O14522	PTPRT	P06241	FYN	Y918	R917L	917	Missense	proximal	-1	no	4.062	6.413	EPSD	TCGA;COSMIC	3.469	Up-regulation
TK_Src_SrcA_FYN_Y	O14522	PTPRT	P06241	FYN	Y918	D925G	925	Missense	distal	7	no	4.062	4.059	EPSD	TCGA	3.469	Down-regulation
TK_Src_SrcA_FYN_Y	O14522	PTPRT	P06241	FYN	Y918	R913L	913	Missense	distal	-5	no	4.062	3.393	EPSD	TCGA;COSMIC	3.469	Loss
TK_Src_SrcA_FYN_Y	O14522	PTPRT	P06241	FYN	Y918	S923F	923	Missense	distal	5	no	4.062	3.964	EPSD	TCGA;COSMIC	3.469	Down-regulation
TK_Src_SrcA_FYN_Y	O14522	PTPRT	P06241	FYN	Y918	G919E	919	Missense	proximal	1	no	4.062	3.067	EPSD	TCGA	3.469	Loss
TK_Src_SrcA_FYN_Y	O14522	PTPRT	P06241	FYN	Y918	G919R	919	Missense	proximal	1	no	4.062	2.298	EPSD	TCGA	3.469	Loss
TK_Src_SrcA_FYN_Y	O14522	PTPRT	P06241	FYN	Y918	N916I	916	Missense	proximal	-2	no	4.062	3.282	EPSD	TCGA;COSMIC	3.469	Loss
TK_Src_SrcA_FYN_Y	O14522	PTPRT	P06241	FYN	Y918	N914T	914	Missense	distal	-4	no	4.062	4.278	EPSD	TCGA;COSMIC	3.469	Up-regulation
TK_Src_SrcA_FYN_Y	O14522	PTPRT	P06241	FYN	Y918	N920S	920	Missense	proximal	2	no	4.062	2.981	EPSD	TCGA;COSMIC	3.469	Loss
TK_Src_SrcA_FYN_Y	O14522	PTPRT	P06241	FYN	Y1008	G1009E	1009	Missense	proximal	1	no	7.020	6.026	EPSD	TCGA;COSMIC	3.469	Down-regulation
TK_Src_SrcA_FYN_Y	O14522	PTPRT	P06241	FYN	Y1008	G1009R	1009	Missense	proximal	1	no	7.020	5.256	EPSD	TCGA;COSMIC;CCLE	3.469	Down-regulation
TK_Src_SrcA_FYN_Y	O14522	PTPRT	P06241	FYN	Y1008	D1010N	1010	Missense	proximal	2	no	7.020	7.138	EPSD	TCGA	3.469	Up-regulation
TK_Src_SrcA_FYN_Y	P40763	STAT3	P06241	FYN	Y22	S25N	25	Missense	distal	3	no	3.772	3.558	EPSD	TCGA;COSMIC	3.469	Down-regulation
TK_Src_SrcA_FYN_Y	P40763	STAT3	P06241	FYN	Y22	M28K	28	Missense	distal	6	no	3.772	3.543	EPSD	TCGA;ICGC;COSMIC	3.469	Down-regulation
TK_Src_SrcA_FYN_Y	P40763	STAT3	P06241	FYN	Y22	L21V	21	Missense	proximal	-1	no	3.772	5.467	EPSD	TCGA	3.469	Up-regulation
TK_Src_SrcA_FYN_Y	P40763	STAT3	P06241	FYN	Y446	E444K	444	Missense	proximal	-2	no	4.534	3.904	EPSD	TCGA;ICGC;COSMIC	3.469	Down-regulation
TK_Src_SrcA_FYN_Y	P40763	STAT3	P06241	FYN	Y446	T440I	440	Missense	distal	-6	no	4.534	3.534	EPSD	TCGA	3.469	Down-regulation
TK_Src_SrcA_FYN_Y	P40763	STAT3	P06241	FYN	Y640	S636F	636	Missense	distal	-4	no	4.147	2.098	EPSD	TCGA;ICGC;COSMIC	3.469	Loss
TK_Src_SrcA_FYN_Y	P40763	STAT3	P06241	FYN	Y640	N647I	647	Missense	distal	7	no	4.147	4.094	EPSD	TCGA;ICGC;COSMIC	3.469	Down-regulation
TK_Src_SrcA_FYN_Y	P40763	STAT3	P06241	FYN	Y640	Q644R	644	Missense	distal	4	no	4.147	3.897	EPSD	TCGA;ICGC	3.469	Down-regulation
TK_Src_SrcA_FYN_Y	P40763	STAT3	P06241	FYN	Y640	Y640F	640	Missense	central	0	yes	4.147	0.000	EPSD	TCGA;ICGC;COSMIC;GDSC;CCLE	3.469	Loss
TK_Src_SrcA_FYN_Y	P40763	STAT3	P06241	FYN	Y640	T641I	641	Missense	proximal	1	no	4.147	3.579	EPSD	TCGA;ICGC;COSMIC	3.469	Down-regulation
TK_Src_SrcA_FYN_Y	P40763	STAT3	P06241	FYN	Y640	P639L	639	Missense	proximal	-1	no	4.147	3.842	EPSD	TCGA;ICGC;COSMIC	3.469	Down-regulation
TK_Src_SrcA_FYN_Y	P40763	STAT3	P06241	FYN	Y640	E638K	638	Missense	proximal	-2	no	4.147	3.516	EPSD	TCGA;ICGC;COSMIC	3.469	Down-regulation
TK_Src_SrcA_FYN_Y	P40763	STAT3	P06241	FYN	Y640	K642E	642	Missense	proximal	2	no	4.147	4.756	EPSD	TCGA;ICGC;COSMIC	3.469	Up-regulation
TK_Src_SrcA_FYN_Y	P40763	STAT3	P06241	FYN	Y640	V637M	637	Missense	distal	-3	no	4.147	4.344	EPSD	TCGA;ICGC;COSMIC	3.469	Up-regulation
TK_Src_SrcA_FYN_Y	P40763	STAT3	P06241	FYN	Y640	N647S	647	Missense	distal	7	no	4.147	4.128	EPSD	TCGA;ICGC	3.469	Down-regulation
TK_Src_SrcA_FYN_Y	P12318	FCGR2A	P06241	FYN	Y281	E282A	282	Missense	proximal	1	no	4.017	3.440	EPSD	TCGA;ICGC;COSMIC	3.469	Loss
TK_Src_SrcA_FYN_Y	P12318	FCGR2A	P06241	FYN	Y281	D280E	280	Missense	proximal	-1	no	4.017	5.032	EPSD	TCGA;ICGC;COSMIC	3.469	Up-regulation
TK_Src_SrcA_FYN_Y	P12318	FCGR2A	P06241	FYN	Y281	T283A	283	Missense	proximal	2	no	4.017	3.675	EPSD	TCGA;ICGC;COSMIC	3.469	Down-regulation
TK_Src_SrcA_FYN_Y	P12318	FCGR2A	P06241	FYN	Y281	G287S	287	Missense	distal	6	no	4.017	3.901	EPSD	TCGA;ICGC;COSMIC	3.469	Down-regulation
TK_Src_SrcA_FYN_Y	P12318	FCGR2A	P06241	FYN	Y304	I303M	303	Missense	proximal	-1	no	6.199	5.429	EPSD	TCGA;ICGC;COSMIC	3.469	Down-regulation
TK_Src_SrcA_FYN_Y	P12318	FCGR2A	P06241	FYN	Y304	D311H	311	Missense	distal	7	no	6.199	6.159	EPSD	TCGA;ICGC;COSMIC	3.469	Down-regulation
TK_Src_SrcA_FYN_Y	P12318	FCGR2A	P06241	FYN	Y304	K301I	301	Missense	distal	-3	no	6.199	4.180	EPSD	TCGA;ICGC;COSMIC	3.469	Down-regulation
TK_Src_SrcA_FYN_Y	P12318	FCGR2A	P06241	FYN	Y304	P308S	308	Missense	distal	4	no	6.199	6.146	EPSD	TCGA;ICGC;COSMIC	3.469	Down-regulation
TK_Src_SrcA_FYN_Y	P12318	FCGR2A	P06241	FYN	Y304	D299Y	299	Missense	distal	-5	no	6.199	4.830	EPSD	TCGA	3.469	Down-regulation
TK_Src_SrcA_FYN_Y	P35637	FUS	P06241	FYN	Y468	D471G	471	Missense	distal	3	no	5.597	6.461	EPSD	TCGA;COSMIC	3.469	Up-regulation
TK_Src_SrcA_FYN_Y	P35637	FUS	P06241	FYN	Y468	R473H	473	Missense	distal	5	no	5.597	5.113	EPSD	TCGA;COSMIC	3.469	Down-regulation
TK_Src_SrcA_FYN_Y	P35637	FUS	P06241	FYN	Y468	R472H	472	Missense	distal	4	no	5.597	5.527	EPSD	TCGA;ICGC;COSMIC	3.469	Down-regulation
TK_Src_SrcA_FYN_Y	Q06124	PTPN11	P06241	FYN	Y304	V301A	301	Missense	distal	-3	no	3.867	4.765	EPSD	TCGA;ICGC;COSMIC	3.469	Up-regulation
TK_Src_SrcA_FYN_Y	Q06124	PTPN11	P06241	FYN	Y304	I309M	309	Missense	distal	5	no	3.867	4.127	EPSD	TCGA;ICGC;COSMIC	3.469	Up-regulation
TK_Src_SrcA_FYN_Y	Q06124	PTPN11	P06241	FYN	Y304	N308D	308	Missense	distal	4	no	3.867	3.613	EPSD	TCGA;ICGC;COSMIC	3.469	Down-regulation
TK_Src_SrcA_FYN_Y	Q9NQC3	RTN4	P06241	FYN	Y384	M380V	380	Missense	distal	-4	no	3.914	3.073	EPSD	TCGA;COSMIC	3.469	Loss
TK_Src_SrcA_FYN_Y	Q9NQC3	RTN4	P06241	FYN	Y384	P379A	379	Missense	distal	-5	no	3.914	3.709	EPSD	TCGA;COSMIC	3.469	Down-regulation
TK_Src_SrcA_FYN_Y	Q9NQC3	RTN4	P06241	FYN	Y384	Y384C	384	Missense	central	0	yes	3.914	0.000	EPSD	TCGA;COSMIC	3.469	Loss
TK_Src_SrcA_FYN_Y	Q9NQC3	RTN4	P06241	FYN	Y694	I697T	697	Missense	distal	3	no	4.853	4.393	PhosphoSitePlus	TCGA;COSMIC	3.469	Down-regulation
TK_Src_SrcA_FYN_Y	Q9NQC3	RTN4	P06241	FYN	Y718	A722V	722	Missense	distal	4	no	4.748	4.698	EPSD	TCGA	3.469	Down-regulation
TK_Src_SrcA_FYN_Y	Q9NQC3	RTN4	P06241	FYN	Y718	A722T	722	Missense	distal	4	no	4.748	4.807	EPSD	TCGA;COSMIC	3.469	Up-regulation
TK_Src_SrcA_FYN_Y	Q9NQC3	RTN4	P06241	FYN	Y840	D844Y	844	Missense	distal	4	no	5.368	5.379	EPSD	TCGA;COSMIC	3.469	Up-regulation
TK_Src_SrcA_FYN_Y	Q9NQC3	RTN4	P06241	FYN	Y840	V839A	839	Missense	proximal	-1	no	5.368	2.692	EPSD	TCGA;COSMIC	3.469	Loss
TK_Src_SrcA_FYN_Y	Q9NQC3	RTN4	P06241	FYN	Y840	Y840H	840	Missense	central	0	yes	5.368	0.000	EPSD	TCGA	3.469	Loss
TK_Src_SrcA_FYN_Y	Q9NQC3	RTN4	P06241	FYN	Y840	T837I	837	Missense	distal	-3	no	5.368	2.725	EPSD	TCGA	3.469	Loss
TK_Src_SrcA_FYN_Y	Q15762	CD226	P06241	FYN	Y322	T317S	317	Missense	distal	-5	no	6.779	5.912	PhosphoSitePlus	TCGA;COSMIC	3.469	Down-regulation
TK_Src_SrcA_FYN_Y	Q15762	CD226	P06241	FYN	Y322	D315N	315	Missense	distal	-7	no	6.779	6.809	PhosphoSitePlus	TCGA;ICGC;COSMIC	3.469	Up-regulation
TK_Src_SrcA_FYN_Y	Q15762	CD226	P06241	FYN	Y322	V323A	323	Missense	proximal	1	no	6.779	6.724	PhosphoSitePlus	TCGA	3.469	Down-regulation
TK_Src_SrcA_FYN_Y	P35612	ADD2	P06241	FYN	Y377	R384G	384	Missense	distal	7	no	5.069	5.049	EPSD	TCGA;ICGC;COSMIC	3.469	Down-regulation
TK_Src_SrcA_FYN_Y	P35612	ADD2	P06241	FYN	Y377	G376S	376	Missense	proximal	-1	no	5.069	4.576	EPSD	TCGA;ICGC;COSMIC	3.469	Down-regulation
TK_Src_SrcA_FYN_Y	P35612	ADD2	P06241	FYN	Y377	R384C	384	Missense	distal	7	no	5.069	4.974	EPSD	TCGA;ICGC;COSMIC	3.469	Down-regulation
TK_Src_SrcA_FYN_Y	P35612	ADD2	P06241	FYN	Y489	F485C	485	Missense	distal	-4	no	5.617	6.105	PhosphoSitePlus	TCGA;ICGC;COSMIC	3.469	Up-regulation
TK_Src_SrcA_FYN_Y	P35612	ADD2	P06241	FYN	Y489	P487S	487	Missense	proximal	-2	no	5.617	5.724	PhosphoSitePlus	TCGA;ICGC;COSMIC	3.469	Up-regulation
TK_Src_SrcA_FYN_Y	Q14643	ITPR1	P06241	FYN	Y117	V114A	114	Missense	distal	-3	no	2.645	3.543	EPSD	TCGA;ICGC	3.469	Gain
TK_Src_SrcA_FYN_Y	P10636	MAPT	P06241	FYN	Y18	D13N	13	Missense	distal	-5	no	7.108	6.725	PhosphoSitePlus	TCGA;ICGC;COSMIC	3.469	Down-regulation
TK_Src_SrcA_FYN_Y	P10636	MAPT	P06241	FYN	Y18	R23S	23	Missense	distal	5	no	7.108	6.933	PhosphoSitePlus	TCGA;ICGC;COSMIC	3.469	Down-regulation
TK_Src_SrcA_FYN_Y	P10636	MAPT	P06241	FYN	Y18	H14Y	14	Missense	distal	-4	no	7.108	5.152	PhosphoSitePlus	TCGA;ICGC;COSMIC	3.469	Down-regulation
TK_Src_SrcA_FYN_Y	P10636	MAPT	P06241	FYN	Y18	G21W	21	Missense	distal	3	no	7.108	6.098	PhosphoSitePlus	TCGA;ICGC;COSMIC	3.469	Down-regulation
TK_Src_SrcA_FYN_Y	P10636	MAPT	P06241	FYN	Y18	K24I	24	Missense	distal	6	no	7.108	7.683	PhosphoSitePlus	TCGA;ICGC	3.469	Up-regulation
TK_Src_SrcA_FYN_Y	P10636	MAPT	P06241	FYN	Y29	R23S	23	Missense	distal	-6	no	5.368	5.314	EPSD	TCGA;ICGC;COSMIC	3.469	Down-regulation
TK_Src_SrcA_FYN_Y	P10636	MAPT	P06241	FYN	Y29	K24I	24	Missense	distal	-5	no	5.368	4.067	EPSD	TCGA;ICGC	3.469	Down-regulation
TK_Src_SrcA_FYN_Y	P17612	PRKACA	P06241	FYN	Y205	P208L	208	Missense	distal	3	no	3.662	3.129	EPSD	TCGA;ICGC	3.469	Loss
TK_Src_SrcA_FYN_Y	P17612	PRKACA	P06241	FYN	Y205	G201S	201	Missense	distal	-4	no	3.662	4.122	EPSD	TCGA;ICGC;COSMIC	3.469	Up-regulation
Other_TTK_TTK_ST	Q9Y5T5	USP16	P33981	TTK	S17	P12L	12	Missense	distal	-5	no	17.545	19.069	EPSD	TCGA;ICGC	18.469	Gain
Other_TTK_TTK_ST	Q9Y5T5	USP16	P33981	TTK	T146	E151D	151	Missense	distal	5	no	17.082	18.689	EPSD	TCGA;COSMIC	18.469	Gain
Other_TTK_TTK_ST	Q9Y5T5	USP16	P33981	TTK	S415	E411K	411	Missense	distal	-4	no	24.803	24.826	PhosphoSitePlus;EPSD	TCGA;COSMIC	18.469	Up-regulation
Other_TTK_TTK_ST	Q9Y5T5	USP16	P33981	TTK	S531	D527N	527	Missense	distal	-4	no	19.122	19.109	EPSD	TCGA;COSMIC	18.469	Down-regulation
Other_TTK_TTK_ST	Q9Y5T5	USP16	P33981	TTK	S531	D536Y	536	Missense	distal	5	no	19.122	16.637	EPSD	TCGA;COSMIC	18.469	Loss
Other_TTK_TTK_ST	Q9Y5T5	USP16	P33981	TTK	S552	P553L	553	Missense	proximal	1	no	22.936	22.959	EPSD;PhosphoSitePlus	TCGA;COSMIC	18.469	Up-regulation
Other_TTK_TTK_ST	Q9Y5T5	USP16	P33981	TTK	S552	N558S	558	Missense	distal	6	no	22.936	22.105	EPSD;PhosphoSitePlus	TCGA;COSMIC	18.469	Down-regulation
Other_TTK_TTK_ST	Q9Y5T5	USP16	P33981	TTK	T554	P553L	553	Missense	proximal	-1	no	21.399	22.303	EPSD;PhosphoSitePlus	TCGA;COSMIC	18.469	Up-regulation
Other_TTK_TTK_ST	Q9Y5T5	USP16	P33981	TTK	T554	N558S	558	Missense	distal	4	no	21.399	21.967	EPSD;PhosphoSitePlus	TCGA;COSMIC	18.469	Up-regulation
Other_TTK_TTK_ST	Q9Y5T5	USP16	P33981	TTK	T563	N558S	558	Missense	distal	-5	no	18.474	16.433	EPSD	TCGA;COSMIC	18.469	Loss
Other_TTK_TTK_ST	P33981	TTK	P33981	TTK	T33	N29K	29	Missense	distal	-4	no	23.444	23.486	EPSD;PhosphoSitePlus	TCGA;ICGC	18.469	Up-regulation
Other_TTK_TTK_ST	P33981	TTK	P33981	TTK	T33	L32V	32	Missense	proximal	-1	no	23.444	23.038	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	18.469	Down-regulation
Other_TTK_TTK_ST	P33981	TTK	P33981	TTK	S37	L32V	32	Missense	distal	-5	no	26.216	25.129	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	18.469	Down-regulation
Other_TTK_TTK_ST	P33981	TTK	P33981	TTK	T46	V52A	52	Missense	distal	6	no	18.064	19.984	EPSD	TCGA;ICGC;COSMIC	18.469	Gain
Other_TTK_TTK_ST	P33981	TTK	P33981	TTK	S49	V52A	52	Missense	distal	3	no	19.054	18.109	EPSD	TCGA;ICGC;COSMIC	18.469	Loss
Other_TTK_TTK_ST	P33981	TTK	P33981	TTK	T210	G217S	217	Missense	distal	7	no	20.797	21.301	EPSD	TCGA;ICGC;COSMIC	18.469	Up-regulation
Other_TTK_TTK_ST	P33981	TTK	P33981	TTK	T210	L203V	203	Missense	distal	-7	no	20.797	23.251	EPSD	TCGA;ICGC	18.469	Up-regulation
Other_TTK_TTK_ST	P33981	TTK	P33981	TTK	T288	S291L	291	Missense	distal	3	no	20.915	21.922	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	18.469	Up-regulation
Other_TTK_TTK_ST	P33981	TTK	P33981	TTK	T288	T288I	288	Missense	central	0	yes	20.915	0.000	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	18.469	Loss
Other_TTK_TTK_ST	P33981	TTK	P33981	TTK	T301	M297I	297	Missense	distal	-4	no	21.400	21.387	EPSD	TCGA;ICGC;COSMIC	18.469	Down-regulation
Other_TTK_TTK_ST	P33981	TTK	P33981	TTK	T301	R307Q	307	Missense	distal	6	no	21.400	22.698	EPSD	TCGA;ICGC;COSMIC	18.469	Up-regulation
Other_TTK_TTK_ST	P33981	TTK	P33981	TTK	T360	T360K	360	Missense	central	0	yes	20.869	0.000	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	18.469	Loss
Other_TTK_TTK_ST	P33981	TTK	P33981	TTK	S362	T360K	360	Missense	proximal	-2	no	20.350	20.035	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	18.469	Down-regulation
Other_TTK_TTK_ST	P33981	TTK	P33981	TTK	S363	T360K	360	Missense	distal	-3	no	22.150	21.711	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	18.469	Down-regulation
Other_TTK_TTK_ST	P33981	TTK	P33981	TTK	T371	E373Q	373	Missense	proximal	2	no	19.844	20.291	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	18.469	Up-regulation
Other_TTK_TTK_ST	P33981	TTK	P33981	TTK	S382	P380A	380	Missense	proximal	-2	no	19.034	19.303	EPSD	TCGA;ICGC;COSMIC	18.469	Up-regulation
Other_TTK_TTK_ST	P33981	TTK	P33981	TTK	T564	E571K	571	Missense	distal	7	no	23.546	22.874	EPSD;PhosphoSitePlus	TCGA;COSMIC	18.469	Down-regulation
Other_TTK_TTK_ST	P33981	TTK	P33981	TTK	T564	D566G	566	Missense	proximal	2	no	23.546	22.408	EPSD;PhosphoSitePlus	TCGA;COSMIC	18.469	Down-regulation
Other_TTK_TTK_ST	P33981	TTK	P33981	TTK	S582	L575W	575	Missense	distal	-7	no	20.360	20.345	EPSD;PhosphoSitePlus	TCGA;COSMIC	18.469	Down-regulation
Other_TTK_TTK_ST	P33981	TTK	P33981	TTK	S582	L575F	575	Missense	distal	-7	no	20.360	19.134	EPSD;PhosphoSitePlus	TCGA;COSMIC	18.469	Down-regulation
Other_TTK_TTK_ST	P33981	TTK	P33981	TTK	S582	S582I	582	Missense	central	0	yes	20.360	0.000	EPSD;PhosphoSitePlus	TCGA;COSMIC	18.469	Loss
Other_TTK_TTK_ST	P33981	TTK	P33981	TTK	S582	S582G	582	Missense	central	0	yes	20.360	0.000	EPSD;PhosphoSitePlus	TCGA;COSMIC	18.469	Loss
Other_TTK_TTK_ST	P33981	TTK	P33981	TTK	T675	T676A	676	Missense	proximal	1	no	23.394	23.363	EPSD;PhosphoSitePlus	TCGA;COSMIC	18.469	Down-regulation
Other_TTK_TTK_ST	P33981	TTK	P33981	TTK	T675	T675K	675	Missense	central	0	yes	23.394	0.000	EPSD;PhosphoSitePlus	TCGA;COSMIC	18.469	Loss
Other_TTK_TTK_ST	P33981	TTK	P33981	TTK	T675	A668E	668	Missense	distal	-7	no	23.394	23.390	EPSD;PhosphoSitePlus	TCGA;COSMIC	18.469	Down-regulation
Other_TTK_TTK_ST	P33981	TTK	P33981	TTK	T675	S677G	677	Missense	proximal	2	no	23.394	23.552	EPSD;PhosphoSitePlus	TCGA	18.469	Up-regulation
Other_TTK_TTK_ST	P33981	TTK	P33981	TTK	T675	A668G	668	Missense	distal	-7	no	23.394	22.357	EPSD;PhosphoSitePlus	TCGA	18.469	Down-regulation
Other_TTK_TTK_ST	P33981	TTK	P33981	TTK	T676	T676A	676	Missense	central	0	yes	22.808	0.000	EPSD;PhosphoSitePlus	TCGA;COSMIC	18.469	Loss
Other_TTK_TTK_ST	P33981	TTK	P33981	TTK	T676	T675K	675	Missense	proximal	-1	no	22.808	21.122	EPSD;PhosphoSitePlus	TCGA;COSMIC	18.469	Down-regulation
Other_TTK_TTK_ST	P33981	TTK	P33981	TTK	T676	Q683R	683	Missense	distal	7	no	22.808	23.732	EPSD;PhosphoSitePlus	TCGA;COSMIC	18.469	Up-regulation
Other_TTK_TTK_ST	P33981	TTK	P33981	TTK	T676	S677G	677	Missense	proximal	1	no	22.808	22.792	EPSD;PhosphoSitePlus	TCGA	18.469	Down-regulation
Other_TTK_TTK_ST	P33981	TTK	P33981	TTK	S677	T676A	676	Missense	proximal	-1	no	22.366	19.471	EPSD;PhosphoSitePlus	TCGA;COSMIC	18.469	Down-regulation
Other_TTK_TTK_ST	P33981	TTK	P33981	TTK	S677	T675K	675	Missense	proximal	-2	no	22.366	22.051	EPSD;PhosphoSitePlus	TCGA;COSMIC	18.469	Down-regulation
Other_TTK_TTK_ST	P33981	TTK	P33981	TTK	S677	Q683R	683	Missense	distal	6	no	22.366	21.068	EPSD;PhosphoSitePlus	TCGA;COSMIC	18.469	Down-regulation
Other_TTK_TTK_ST	P33981	TTK	P33981	TTK	S677	S677G	677	Missense	central	0	yes	22.366	0.000	EPSD;PhosphoSitePlus	TCGA	18.469	Loss
Other_TTK_TTK_ST	P33981	TTK	P33981	TTK	T686	Q683R	683	Missense	distal	-3	no	28.556	27.308	EPSD;PhosphoSitePlus	TCGA;COSMIC	18.469	Down-regulation
Other_TTK_TTK_ST	P33981	TTK	P33981	TTK	T686	Y689C	689	Missense	distal	3	no	28.556	24.075	EPSD;PhosphoSitePlus	TCGA;COSMIC	18.469	Down-regulation
Other_TTK_TTK_ST	P33981	TTK	P33981	TTK	T686	G685V	685	Missense	proximal	-1	no	28.556	27.374	EPSD;PhosphoSitePlus	TCGA;COSMIC	18.469	Down-regulation
Other_TTK_TTK_ST	P33981	TTK	P33981	TTK	S742	D749V	749	Missense	distal	7	no	21.676	22.283	EPSD;PhosphoSitePlus	TCGA;COSMIC	18.469	Up-regulation
Other_TTK_TTK_ST	P33981	TTK	P33981	TTK	S742	S742Y	742	Missense	central	0	yes	21.676	0.000	EPSD;PhosphoSitePlus	TCGA	18.469	Loss
Other_TTK_TTK_ST	P33981	TTK	P33981	TTK	S742	I741M	741	Missense	proximal	-1	no	21.676	20.003	EPSD;PhosphoSitePlus	TCGA;COSMIC	18.469	Down-regulation
Other_TTK_TTK_ST	P33981	TTK	P33981	TTK	S742	K743T	743	Missense	proximal	1	no	21.676	21.699	EPSD;PhosphoSitePlus	TCGA;COSMIC	18.469	Up-regulation
Other_TTK_TTK_ST	P33981	TTK	P33981	TTK	T795	V791L	791	Missense	distal	-4	no	23.945	23.887	EPSD;PhosphoSitePlus	TCGA	18.469	Down-regulation
Other_TTK_TTK_ST	P33981	TTK	P33981	TTK	T805	G804A	804	Missense	proximal	-1	no	21.694	20.935	EPSD;PhosphoSitePlus	TCGA;COSMIC	18.469	Down-regulation
Other_TTK_TTK_ST	P33981	TTK	P33981	TTK	T805	K803N	803	Missense	proximal	-2	no	21.694	22.071	EPSD;PhosphoSitePlus	TCGA;COSMIC	18.469	Up-regulation
Other_TTK_TTK_ST	P33981	TTK	P33981	TTK	T805	V812I	812	Missense	distal	7	no	21.694	21.365	EPSD;PhosphoSitePlus	TCGA;COSMIC	18.469	Down-regulation
Other_TTK_TTK_ST	P33981	TTK	P33981	TTK	T806	G804A	804	Missense	proximal	-2	no	21.560	21.446	EPSD;PhosphoSitePlus	TCGA;COSMIC	18.469	Down-regulation
Other_TTK_TTK_ST	P33981	TTK	P33981	TTK	T806	K803N	803	Missense	distal	-3	no	21.560	22.046	EPSD;PhosphoSitePlus	TCGA;COSMIC	18.469	Up-regulation
Other_TTK_TTK_ST	P33981	TTK	P33981	TTK	T806	V812I	812	Missense	distal	6	no	21.560	21.024	EPSD;PhosphoSitePlus	TCGA;COSMIC	18.469	Down-regulation
Other_TTK_TTK_ST	P33981	TTK	P33981	TTK	S821	G814C	814	Missense	distal	-7	no	23.140	24.212	EPSD;PhosphoSitePlus	TCGA;COSMIC	18.469	Up-regulation
Other_TTK_TTK_ST	P33981	TTK	P33981	TTK	S821	S824F	824	Missense	distal	3	no	23.140	18.781	EPSD;PhosphoSitePlus	TCGA;COSMIC	18.469	Down-regulation
Other_TTK_TTK_ST	P33981	TTK	P33981	TTK	S821	L816R	816	Missense	distal	-5	no	23.140	22.095	EPSD;PhosphoSitePlus	TCGA;COSMIC	18.469	Down-regulation
Other_TTK_TTK_ST	P33981	TTK	P33981	TTK	S821	S821Y	821	Missense	central	0	yes	23.140	0.000	EPSD;PhosphoSitePlus	TCGA;COSMIC	18.469	Loss
Other_TTK_TTK_ST	P33981	TTK	P33981	TTK	S824	S824F	824	Missense	central	0	yes	23.867	0.000	EPSD;PhosphoSitePlus	TCGA;COSMIC	18.469	Loss
Other_TTK_TTK_ST	P33981	TTK	P33981	TTK	S824	S821Y	821	Missense	distal	-3	no	23.867	19.148	EPSD;PhosphoSitePlus	TCGA;COSMIC	18.469	Down-regulation
Other_TTK_TTK_ST	P33981	TTK	P33981	TTK	T831	S824F	824	Missense	distal	-7	no	20.126	17.498	EPSD	TCGA;COSMIC	18.469	Loss
Other_TTK_TTK_ST	P33981	TTK	P33981	TTK	S845	G839S	839	Missense	distal	-6	no	20.477	20.573	EPSD;PhosphoSitePlus	TCGA;COSMIC	18.469	Up-regulation
Other_TTK_TTK_ST	P33981	TTK	P33981	TTK	S847	R854G	854	Missense	distal	7	no	18.845	17.165	EPSD;PhosphoSitePlus	TCGA;COSMIC;CCLE	18.469	Loss
Other_TTK_TTK_ST	P33981	TTK	P33981	TTK	S847	R854K	854	Missense	distal	7	no	18.845	17.965	EPSD;PhosphoSitePlus	TCGA;COSMIC	18.469	Loss
Other_TTK_TTK_ST	P33981	TTK	P33981	TTK	T849	R854G	854	Missense	distal	5	no	16.165	19.171	EPSD;PhosphoSitePlus	TCGA;COSMIC;CCLE	18.469	Gain
Other_TTK_TTK_ST	P07900	HSP90AA1	P33981	TTK	T7	P2L	2	Missense	distal	-5	no	18.343	19.867	EPSD	TCGA;ICGC;COSMIC	18.469	Gain
Other_TTK_TTK_ST	P07900	HSP90AA1	P33981	TTK	T305	P301H	301	Missense	distal	-4	no	20.048	20.103	EPSD	TCGA;ICGC;COSMIC	18.469	Up-regulation
Other_TTK_TTK_ST	P07900	HSP90AA1	P33981	TTK	S476	D472H	472	Missense	distal	-4	no	19.384	19.366	EPSD	TCGA;COSMIC	18.469	Down-regulation
Other_TTK_TTK_ST	Q53HL2	CDCA8	P33981	TTK	S23	A22T	22	Missense	proximal	-1	no	17.262	20.157	EPSD	TCGA;ICGC;COSMIC	18.469	Gain
Other_TTK_TTK_ST	Q53HL2	CDCA8	P33981	TTK	T88	E95K	95	Missense	distal	7	no	25.265	24.593	EPSD;PhosphoSitePlus	TCGA;ICGC	18.469	Down-regulation
Other_TTK_TTK_ST	Q53HL2	CDCA8	P33981	TTK	T100	E95K	95	Missense	distal	-5	no	20.199	19.010	EPSD	TCGA;ICGC	18.469	Down-regulation
Other_TTK_TTK_ST	Q53HL2	CDCA8	P33981	TTK	T169	A173V	173	Missense	distal	4	no	26.238	26.113	EPSD;PhosphoSitePlus	TCGA;ICGC	18.469	Down-regulation
Other_TTK_TTK_ST	Q53HL2	CDCA8	P33981	TTK	T169	R176Q	176	Missense	distal	7	no	26.238	25.314	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	18.469	Down-regulation
Other_TTK_TTK_ST	Q53HL2	CDCA8	P33981	TTK	T199	G201D	201	Missense	proximal	2	no	18.699	19.837	EPSD	TCGA;ICGC;COSMIC	18.469	Up-regulation
Other_TTK_TTK_ST	Q53HL2	CDCA8	P33981	TTK	T199	R203H	203	Missense	distal	4	no	18.699	19.467	EPSD	TCGA;ICGC;COSMIC	18.469	Up-regulation
Other_TTK_TTK_ST	Q53HL2	CDCA8	P33981	TTK	T204	R203H	203	Missense	proximal	-1	no	17.994	19.480	EPSD	TCGA;ICGC;COSMIC	18.469	Gain
Other_TTK_TTK_ST	Q53HL2	CDCA8	P33981	TTK	T204	R210Q	210	Missense	distal	6	no	17.994	19.292	EPSD	TCGA;ICGC	18.469	Gain
Other_TTK_TTK_ST	Q53HL2	CDCA8	P33981	TTK	S224	E226Q	226	Missense	proximal	2	no	18.527	18.974	EPSD	TCGA;ICGC;COSMIC	18.469	Up-regulation
Other_TTK_TTK_ST	Q53HL2	CDCA8	P33981	TTK	S224	L221R	221	Missense	distal	-3	no	18.527	18.997	EPSD	TCGA;ICGC	18.469	Up-regulation
Other_TTK_TTK_ST	Q53HL2	CDCA8	P33981	TTK	S224	D223N	223	Missense	proximal	-1	no	18.527	19.755	EPSD	TCGA;ICGC;COSMIC	18.469	Up-regulation
Other_TTK_TTK_ST	Q53HL2	CDCA8	P33981	TTK	T230	E226Q	226	Missense	distal	-4	no	20.157	20.198	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	18.469	Up-regulation
Other_TTK_TTK_ST	Q53HL2	CDCA8	P33981	TTK	T230	D223N	223	Missense	distal	-7	no	20.157	20.930	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	18.469	Up-regulation
Other_TTK_TTK_ST	Q53HL2	CDCA8	P33981	TTK	S238	R240Q	240	Missense	proximal	2	no	24.657	26.329	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	18.469	Up-regulation
Other_TTK_TTK_ST	P54132	BLM	P33981	TTK	S42	S48F	48	Missense	distal	6	no	19.623	18.513	EPSD	TCGA;ICGC;COSMIC	18.469	Down-regulation
Other_TTK_TTK_ST	P54132	BLM	P33981	TTK	S43	S48F	48	Missense	distal	5	no	19.360	20.474	EPSD	TCGA;ICGC;COSMIC	18.469	Up-regulation
Other_TTK_TTK_ST	P54132	BLM	P33981	TTK	T121	T125P	125	Missense	distal	4	no	19.222	18.615	EPSD	TCGA;ICGC;COSMIC	18.469	Down-regulation
Other_TTK_TTK_ST	P54132	BLM	P33981	TTK	T125	T125P	125	Missense	central	0	yes	19.059	0.000	EPSD	TCGA;ICGC;COSMIC	18.469	Loss
Other_TTK_TTK_ST	P54132	BLM	P33981	TTK	T125	R132W	132	Missense	distal	7	no	19.059	17.140	EPSD	TCGA;ICGC;COSMIC	18.469	Loss
Other_TTK_TTK_ST	P54132	BLM	P33981	TTK	T150	D153Y	153	Missense	distal	3	no	17.737	20.995	EPSD	TCGA;ICGC;COSMIC	18.469	Gain
Other_TTK_TTK_ST	P54132	BLM	P33981	TTK	S316	S310C	310	Missense	distal	-6	no	19.672	19.772	EPSD	TCGA;ICGC	18.469	Up-regulation
Other_TTK_TTK_ST	P54132	BLM	P33981	TTK	S328	S328C	328	Missense	central	0	yes	20.257	0.000	EPSD	TCGA;ICGC;COSMIC	18.469	Loss
Other_TTK_TTK_ST	P54132	BLM	P33981	TTK	S328	L335F	335	Missense	distal	7	no	20.257	18.876	EPSD	TCGA;ICGC;COSMIC	18.469	Down-regulation
Other_TTK_TTK_ST	P54132	BLM	P33981	TTK	T337	D340Y	340	Missense	distal	3	no	16.573	19.832	EPSD	TCGA;ICGC;COSMIC	18.469	Gain
Other_TTK_TTK_ST	P54132	BLM	P33981	TTK	T357	M350I	350	Missense	distal	-7	no	18.625	17.483	EPSD	TCGA;ICGC;COSMIC	18.469	Loss
Other_TTK_TTK_ST	P54132	BLM	P33981	TTK	S517	L511I	511	Missense	distal	-6	no	19.139	19.205	EPSD	TCGA;ICGC;COSMIC	18.469	Up-regulation
Other_TTK_TTK_ST	P54132	BLM	P33981	TTK	T742	T747A	747	Missense	distal	5	no	18.976	17.900	EPSD	TCGA;ICGC;COSMIC	18.469	Loss
Other_TTK_TTK_ST	P54132	BLM	P33981	TTK	T742	D743N	743	Missense	proximal	1	no	18.976	18.971	EPSD	TCGA;ICGC;COSMIC	18.469	Down-regulation
Other_TTK_TTK_ST	P54132	BLM	P33981	TTK	T742	I749N	749	Missense	distal	7	no	18.976	19.304	EPSD	TCGA;ICGC;COSMIC	18.469	Up-regulation
Other_TTK_TTK_ST	P54132	BLM	P33981	TTK	T903	R910T	910	Missense	distal	7	no	19.109	17.220	EPSD	TCGA;ICGC;COSMIC	18.469	Loss
Other_TTK_TTK_ST	P54132	BLM	P33981	TTK	T903	D902H	902	Missense	proximal	-1	no	19.109	18.118	EPSD	TCGA;ICGC;COSMIC	18.469	Loss
Other_TTK_TTK_ST	P54132	BLM	P33981	TTK	S1195	E1193Q	1193	Missense	proximal	-2	no	20.068	20.490	EPSD	TCGA;ICGC;COSMIC	18.469	Up-regulation
Other_TTK_TTK_ST	P54132	BLM	P33981	TTK	S1195	N1194H	1194	Missense	proximal	-1	no	20.068	17.850	EPSD	TCGA;ICGC;COSMIC	18.469	Loss
Other_TTK_TTK_ST	P54132	BLM	P33981	TTK	S1196	E1193Q	1193	Missense	distal	-3	no	18.832	18.804	EPSD	TCGA;ICGC;COSMIC	18.469	Down-regulation
Other_TTK_TTK_ST	P54132	BLM	P33981	TTK	S1196	N1194H	1194	Missense	proximal	-2	no	18.832	18.225	EPSD	TCGA;ICGC;COSMIC	18.469	Loss
Other_TTK_TTK_ST	P54132	BLM	P33981	TTK	S1390	Q1387E	1387	Missense	distal	-3	no	18.823	18.851	EPSD	TCGA;ICGC;COSMIC	18.469	Up-regulation
Other_TTK_TTK_ST	P54132	BLM	P33981	TTK	S1390	A1388T	1388	Missense	proximal	-2	no	18.823	18.998	EPSD	TCGA;ICGC;COSMIC	18.469	Up-regulation
Other_TTK_TTK_ST	P00519	ABL1	P33981	TTK	T545	P548S	548	Missense	distal	3	no	16.623	20.828	EPSD	TCGA;COSMIC	18.469	Gain
Other_TTK_TTK_ST	P38646	HSPA9	P33981	TTK	T177	V170M	170	Missense	distal	-7	no	18.852	17.899	EPSD	TCGA;ICGC;COSMIC	18.469	Loss
Other_TTK_TTK_ST	P38646	HSPA9	P33981	TTK	T294	F290L	290	Missense	distal	-4	no	19.101	19.140	EPSD	TCGA;ICGC;COSMIC	18.469	Up-regulation
Other_TTK_TTK_ST	P38646	HSPA9	P33981	TTK	T294	R292T	292	Missense	proximal	-2	no	19.101	19.636	EPSD	TCGA;ICGC;COSMIC	18.469	Up-regulation
Other_TTK_TTK_ST	P38646	HSPA9	P33981	TTK	T294	K288N	288	Missense	distal	-6	no	19.101	19.060	EPSD	TCGA;ICGC;COSMIC	18.469	Down-regulation
Other_TTK_TTK_ST	P38646	HSPA9	P33981	TTK	T294	K291N	291	Missense	distal	-3	no	19.101	19.587	EPSD	TCGA;ICGC	18.469	Up-regulation
Other_TTK_TTK_ST	P38646	HSPA9	P33981	TTK	T299	Q306H	306	Missense	distal	7	no	19.168	19.281	EPSD	TCGA;ICGC;COSMIC	18.469	Up-regulation
Other_TTK_TTK_ST	P38646	HSPA9	P33981	TTK	T299	R292T	292	Missense	distal	-7	no	19.168	19.409	EPSD	TCGA;ICGC;COSMIC	18.469	Up-regulation
Other_TTK_TTK_ST	P38646	HSPA9	P33981	TTK	S644	L640V	640	Missense	distal	-4	no	18.429	18.486	EPSD	TCGA;ICGC;COSMIC	18.469	Gain
Other_TTK_TTK_ST	O60566	BUB1B	P33981	TTK	T474	E470K	470	Missense	distal	-4	no	18.988	19.011	EPSD	TCGA;ICGC	18.469	Up-regulation
Other_TTK_TTK_ST	O60566	BUB1B	P33981	TTK	S543	P544S	544	Missense	proximal	1	no	23.191	23.203	EPSD;PhosphoSitePlus	TCGA;COSMIC;GDSC	18.469	Up-regulation
Other_TTK_TTK_ST	O60566	BUB1B	P33981	TTK	S569	D572Y	572	Missense	distal	3	no	17.336	20.594	EPSD	TCGA	18.469	Gain
Other_TTK_TTK_ST	O60566	BUB1B	P33981	TTK	S670	L669P	669	Missense	proximal	-1	no	23.965	23.061	EPSD;PhosphoSitePlus	TCGA;COSMIC	18.469	Down-regulation
Other_TTK_TTK_ST	O60566	BUB1B	P33981	TTK	S670	R677H	677	Missense	distal	7	no	23.965	23.155	EPSD;PhosphoSitePlus	TCGA;COSMIC;GDSC;CCLE	18.469	Down-regulation
Other_TTK_TTK_ST	Q9Y6D9	MAD1L1	P33981	TTK	T13	S16F	16	Missense	distal	3	no	19.053	14.694	EPSD	TCGA;ICGC;COSMIC	18.469	Loss
Other_TTK_TTK_ST	Q9Y6D9	MAD1L1	P33981	TTK	T13	E6K	6	Missense	distal	-7	no	19.053	18.204	EPSD	TCGA;ICGC;COSMIC	18.469	Loss
Other_TTK_TTK_ST	Q9Y6D9	MAD1L1	P33981	TTK	S22	S16F	16	Missense	distal	-6	no	23.151	23.135	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	18.469	Down-regulation
Other_TTK_TTK_ST	Q9Y6D9	MAD1L1	P33981	TTK	S22	R24L	24	Missense	proximal	2	no	23.151	23.852	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	18.469	Up-regulation
Other_TTK_TTK_ST	Q9Y6D9	MAD1L1	P33981	TTK	S62	I65M	65	Missense	distal	3	no	22.273	20.413	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	18.469	Down-regulation
Other_TTK_TTK_ST	Q9Y6D9	MAD1L1	P33981	TTK	S62	R69W	69	Missense	distal	7	no	22.273	20.354	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	18.469	Down-regulation
Other_TTK_TTK_ST	Q9Y6D9	MAD1L1	P33981	TTK	S62	R69Q	69	Missense	distal	7	no	22.273	21.349	EPSD;PhosphoSitePlus	TCGA;ICGC	18.469	Down-regulation
Other_TTK_TTK_ST	Q9Y6D9	MAD1L1	P33981	TTK	T91	R98H	98	Missense	distal	7	no	19.834	19.025	EPSD	TCGA;COSMIC	18.469	Down-regulation
Other_TTK_TTK_ST	Q9Y6D9	MAD1L1	P33981	TTK	T91	A89S	89	Missense	proximal	-2	no	19.834	19.654	EPSD	TCGA;ICGC;COSMIC	18.469	Down-regulation
Other_TTK_TTK_ST	Q9Y6D9	MAD1L1	P33981	TTK	T91	A93V	93	Missense	proximal	2	no	19.834	18.333	EPSD	TCGA;ICGC;COSMIC	18.469	Loss
Other_TTK_TTK_ST	Q9Y6D9	MAD1L1	P33981	TTK	S172	D175Y	175	Missense	distal	3	no	18.149	21.407	EPSD	TCGA;COSMIC	18.469	Gain
Other_TTK_TTK_ST	Q9Y6D9	MAD1L1	P33981	TTK	S172	M178L	178	Missense	distal	6	no	18.149	18.971	EPSD	TCGA;COSMIC	18.469	Gain
Other_TTK_TTK_ST	Q9Y6D9	MAD1L1	P33981	TTK	S185	E184K	184	Missense	proximal	-1	no	19.003	20.013	EPSD	TCGA;COSMIC	18.469	Up-regulation
Other_TTK_TTK_ST	Q9Y6D9	MAD1L1	P33981	TTK	S185	R179L	179	Missense	distal	-6	no	19.003	18.978	EPSD	TCGA;COSMIC	18.469	Down-regulation
Other_TTK_TTK_ST	Q9Y6D9	MAD1L1	P33981	TTK	S185	M178L	178	Missense	distal	-7	no	19.003	17.501	EPSD	TCGA;COSMIC	18.469	Loss
Other_TTK_TTK_ST	Q9Y6D9	MAD1L1	P33981	TTK	S185	R179Q	179	Missense	distal	-6	no	19.003	18.783	EPSD	TCGA;COSMIC	18.469	Down-regulation
Other_TTK_TTK_ST	Q9Y6D9	MAD1L1	P33981	TTK	S185	R182H	182	Missense	distal	-3	no	19.003	17.784	EPSD	TCGA;COSMIC;GDSC;CCLE	18.469	Loss
Other_TTK_TTK_ST	Q9Y6D9	MAD1L1	P33981	TTK	T323	R319I	319	Missense	distal	-4	no	23.180	23.218	EPSD;PhosphoSitePlus	TCGA	18.469	Up-regulation
Other_TTK_TTK_ST	Q9Y6D9	MAD1L1	P33981	TTK	T423	Q430H	430	Missense	distal	7	no	20.190	20.304	EPSD	TCGA;COSMIC	18.469	Up-regulation
Other_TTK_TTK_ST	Q9Y6D9	MAD1L1	P33981	TTK	S428	Q430H	430	Missense	proximal	2	no	19.866	17.861	EPSD	TCGA;COSMIC	18.469	Loss
Other_TTK_TTK_ST	Q9Y6D9	MAD1L1	P33981	TTK	S485	S490G	490	Missense	distal	5	no	18.106	20.770	EPSD	TCGA;COSMIC	18.469	Gain
Other_TTK_TTK_ST	Q9Y6D9	MAD1L1	P33981	TTK	S551	R556C	556	Missense	distal	5	no	20.587	21.040	EPSD	TCGA;COSMIC;CCLE	18.469	Up-regulation
Other_TTK_TTK_ST	Q9Y6D9	MAD1L1	P33981	TTK	S551	R554S	554	Missense	distal	3	no	20.587	20.210	EPSD	TCGA;COSMIC	18.469	Down-regulation
Other_TTK_TTK_ST	Q9Y6D9	MAD1L1	P33981	TTK	S551	R556H	556	Missense	distal	5	no	20.587	19.363	EPSD	TCGA;COSMIC	18.469	Down-regulation
Other_TTK_TTK_ST	Q9Y6D9	MAD1L1	P33981	TTK	S551	N548D	548	Missense	distal	-3	no	20.587	18.372	EPSD	TCGA;COSMIC	18.469	Loss
Other_TTK_TTK_ST	Q9Y6D9	MAD1L1	P33981	TTK	S610	K614N	614	Missense	distal	4	no	23.425	22.987	EPSD;PhosphoSitePlus	TCGA;COSMIC	18.469	Down-regulation
Other_TTK_TTK_ST	Q9Y6D9	MAD1L1	P33981	TTK	S610	Q607R	607	Missense	distal	-3	no	23.425	22.177	EPSD;PhosphoSitePlus	TCGA;COSMIC	18.469	Down-regulation
Other_TTK_TTK_ST	Q9Y6D9	MAD1L1	P33981	TTK	T624	V621L	621	Missense	distal	-3	no	23.499	23.959	EPSD;PhosphoSitePlus	TCGA;COSMIC	18.469	Up-regulation
Other_TTK_TTK_ST	Q9Y6D9	MAD1L1	P33981	TTK	T624	R630C	630	Missense	distal	6	no	23.499	22.361	EPSD;PhosphoSitePlus	TCGA;COSMIC	18.469	Down-regulation
Other_TTK_TTK_ST	Q96PE2	ARHGEF17	P33981	TTK	S317	S320L	320	Missense	distal	3	no	18.998	20.004	EPSD	TCGA;ICGC;COSMIC	18.469	Up-regulation
Other_TTK_TTK_ST	Q96PE2	ARHGEF17	P33981	TTK	S317	V323I	323	Missense	distal	6	no	18.998	18.462	EPSD	TCGA;ICGC;COSMIC	18.469	Loss
Other_TTK_TTK_ST	Q96PE2	ARHGEF17	P33981	TTK	S320	S320L	320	Missense	central	0	yes	20.648	0.000	EPSD	TCGA;ICGC;COSMIC	18.469	Loss
Other_TTK_TTK_ST	Q96PE2	ARHGEF17	P33981	TTK	S320	S326I	326	Missense	distal	6	no	20.648	19.585	EPSD	TCGA;ICGC;COSMIC	18.469	Down-regulation
Other_TTK_TTK_ST	Q96PE2	ARHGEF17	P33981	TTK	S320	V323I	323	Missense	distal	3	no	20.648	22.357	EPSD	TCGA;ICGC;COSMIC	18.469	Up-regulation
Other_TTK_TTK_ST	Q96PE2	ARHGEF17	P33981	TTK	S390	G389S	389	Missense	proximal	-1	no	17.876	18.823	EPSD	TCGA;ICGC	18.469	Gain
Other_TTK_TTK_ST	Q96PE2	ARHGEF17	P33981	TTK	T473	T473M	473	Missense	central	0	yes	18.899	0.000	EPSD	TCGA;ICGC;COSMIC	18.469	Loss
Other_TTK_TTK_ST	Q96PE2	ARHGEF17	P33981	TTK	T473	A468T	468	Missense	distal	-5	no	18.899	18.424	EPSD	TCGA;ICGC;COSMIC;GDSC;CCLE	18.469	Loss
Other_TTK_TTK_ST	Q96PE2	ARHGEF17	P33981	TTK	S507	G512D	512	Missense	distal	5	no	18.927	17.064	EPSD	TCGA;ICGC	18.469	Loss
Other_TTK_TTK_ST	Q96PE2	ARHGEF17	P33981	TTK	S507	P513H	513	Missense	distal	6	no	18.927	16.754	EPSD	TCGA;ICGC;COSMIC	18.469	Loss
Other_TTK_TTK_ST	Q96PE2	ARHGEF17	P33981	TTK	T533	P528T	528	Missense	distal	-5	no	18.239	19.365	EPSD	TCGA;ICGC;COSMIC	18.469	Gain
Other_TTK_TTK_ST	Q96PE2	ARHGEF17	P33981	TTK	S568	E570K	570	Missense	proximal	2	no	19.219	18.955	EPSD	TCGA;ICGC;COSMIC	18.469	Down-regulation
Other_TTK_TTK_ST	Q96PE2	ARHGEF17	P33981	TTK	T702	R707C	707	Missense	distal	5	no	20.131	20.584	EPSD	TCGA;ICGC;COSMIC	18.469	Up-regulation
Other_TTK_TTK_ST	Q96PE2	ARHGEF17	P33981	TTK	S735	D736N	736	Missense	proximal	1	no	19.291	19.286	EPSD	TCGA;ICGC;COSMIC	18.469	Down-regulation
Other_TTK_TTK_ST	Q96PE2	ARHGEF17	P33981	TTK	T780	G778D	778	Missense	proximal	-2	no	19.375	19.256	EPSD	TCGA;ICGC;COSMIC	18.469	Down-regulation
Other_TTK_TTK_ST	Q96PE2	ARHGEF17	P33981	TTK	S790	G789C	789	Missense	proximal	-1	no	20.573	18.723	EPSD	TCGA;ICGC;COSMIC	18.469	Down-regulation
Other_TTK_TTK_ST	Q96PE2	ARHGEF17	P33981	TTK	S827	P831S	831	Missense	distal	4	no	19.563	20.625	EPSD	TCGA;ICGC;COSMIC	18.469	Up-regulation
Other_TTK_TTK_ST	Q96PE2	ARHGEF17	P33981	TTK	S827	R834H	834	Missense	distal	7	no	19.563	18.753	EPSD	TCGA;ICGC;COSMIC	18.469	Down-regulation
Other_TTK_TTK_ST	Q96PE2	ARHGEF17	P33981	TTK	T944	R949Q	949	Missense	distal	5	no	23.911	23.448	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	18.469	Down-regulation
Other_TTK_TTK_ST	Q96PE2	ARHGEF17	P33981	TTK	T944	E938K	938	Missense	distal	-6	no	23.911	23.926	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	18.469	Up-regulation
Other_TTK_TTK_ST	Q96PE2	ARHGEF17	P33981	TTK	T944	G945D	945	Missense	proximal	1	no	23.911	23.931	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	18.469	Up-regulation
Other_TTK_TTK_ST	Q96PE2	ARHGEF17	P33981	TTK	T1007	T1007A	1007	Missense	central	0	yes	22.406	0.000	PhosphoSitePlus;EPSD	TCGA;ICGC;COSMIC	18.469	Loss
Other_TTK_TTK_ST	Q9Y6R1	SLC4A4	P33981	TTK	S61	K54N	54	Missense	distal	-7	no	20.985	21.141	EPSD	TCGA	18.469	Up-regulation
Other_TTK_TTK_ST	Q9Y6R1	SLC4A4	P33981	TTK	S61	Y64C	64	Missense	distal	3	no	20.985	16.504	EPSD	TCGA;ICGC;COSMIC	18.469	Loss
Other_TTK_TTK_ST	Q9Y6R1	SLC4A4	P33981	TTK	S61	E62D	62	Missense	proximal	1	no	20.985	20.986	EPSD	TCGA;ICGC;COSMIC	18.469	Up-regulation
Other_TTK_TTK_ST	Q9Y6R1	SLC4A4	P33981	TTK	S61	S61Y	61	Missense	central	0	yes	20.985	0.000	EPSD	TCGA;ICGC;COSMIC	18.469	Loss
Other_TTK_TTK_ST	Q9Y6R1	SLC4A4	P33981	TTK	S61	R59I	59	Missense	proximal	-2	no	20.985	21.482	EPSD	TCGA;ICGC	18.469	Up-regulation
Other_TTK_TTK_ST	Q9Y6R1	SLC4A4	P33981	TTK	S65	Y64C	64	Missense	proximal	-1	no	16.499	19.204	EPSD	TCGA;ICGC;COSMIC	18.469	Gain
Other_TTK_TTK_ST	Q9Y6R1	SLC4A4	P33981	TTK	S77	S76F	76	Missense	proximal	-1	no	19.968	16.996	EPSD	TCGA;ICGC;COSMIC	18.469	Loss
Other_TTK_TTK_ST	Q9Y6R1	SLC4A4	P33981	TTK	S77	S77C	77	Missense	central	0	yes	19.968	0.000	EPSD	TCGA;ICGC;COSMIC	18.469	Loss
Other_TTK_TTK_ST	Q9Y6R1	SLC4A4	P33981	TTK	S77	S79N	79	Missense	proximal	2	no	19.968	21.277	EPSD	TCGA;ICGC;COSMIC	18.469	Up-regulation
Other_TTK_TTK_ST	Q9Y6R1	SLC4A4	P33981	TTK	S77	S79I	79	Missense	proximal	2	no	19.968	20.911	EPSD	TCGA;ICGC;COSMIC	18.469	Up-regulation
Other_TTK_TTK_ST	Q9Y6R1	SLC4A4	P33981	TTK	S223	S219Y	219	Missense	distal	-4	no	23.254	23.267	EPSD	TCGA;ICGC;COSMIC	18.469	Up-regulation
Other_TTK_TTK_ST	Q9Y6R1	SLC4A4	P33981	TTK	S223	N220K	220	Missense	distal	-3	no	23.254	22.768	EPSD	TCGA;ICGC;COSMIC	18.469	Down-regulation
Other_TTK_TTK_ST	Q9Y6R1	SLC4A4	P33981	TTK	S223	S223F	223	Missense	central	0	yes	23.254	0.000	EPSD	TCGA;ICGC;COSMIC	18.469	Loss
Other_TTK_TTK_ST	Q9Y6R1	SLC4A4	P33981	TTK	S223	K229E	229	Missense	distal	6	no	23.254	23.199	EPSD	TCGA;ICGC;COSMIC	18.469	Down-regulation
Other_TTK_TTK_ST	Q9Y6R1	SLC4A4	P33981	TTK	S233	K229E	229	Missense	distal	-4	no	19.105	19.081	EPSD	TCGA;ICGC;COSMIC	18.469	Down-regulation
Other_TTK_TTK_ST	O96017	CHEK2	P33981	TTK	S19	C18S	18	Missense	proximal	-1	no	16.102	18.899	EPSD	TCGA;ICGC;COSMIC	18.469	Gain
Other_TTK_TTK_ST	O96017	CHEK2	P33981	TTK	T43	S42C	42	Missense	proximal	-1	no	20.136	17.339	EPSD	TCGA;ICGC;COSMIC	18.469	Loss
Other_TTK_TTK_ST	O96017	CHEK2	P33981	TTK	S52	S53F	53	Missense	proximal	1	no	20.890	20.907	EPSD	TCGA;ICGC;COSMIC	18.469	Up-regulation
Other_TTK_TTK_ST	O96017	CHEK2	P33981	TTK	S52	S56R	56	Missense	distal	4	no	20.890	19.948	EPSD	TCGA;ICGC;COSMIC	18.469	Down-regulation
Other_TTK_TTK_ST	O96017	CHEK2	P33981	TTK	T68	E70G	70	Missense	proximal	2	no	22.982	21.667	PhosphoSitePlus	TCGA	18.469	Down-regulation
Other_TTK_TTK_ST	Q6IBW4	NCAPH2	P33981	TTK	S95	R101K	101	Missense	distal	6	no	20.265	21.213	EPSD	TCGA;ICGC;COSMIC	18.469	Up-regulation
Other_TTK_TTK_ST	Q6IBW4	NCAPH2	P33981	TTK	S96	R101K	101	Missense	distal	5	no	22.429	23.415	EPSD	TCGA;ICGC;COSMIC	18.469	Up-regulation
Other_TTK_TTK_ST	Q6IBW4	NCAPH2	P33981	TTK	T138	I145T	145	Missense	distal	7	no	27.160	26.760	EPSD	TCGA;ICGC;COSMIC	18.469	Down-regulation
Other_TTK_TTK_ST	Q6IBW4	NCAPH2	P33981	TTK	T138	I145V	145	Missense	distal	7	no	27.160	27.489	EPSD	TCGA;ICGC;COSMIC	18.469	Up-regulation
Other_TTK_TTK_ST	Q6IBW4	NCAPH2	P33981	TTK	S200	S200P	200	Missense	central	0	yes	19.983	0.000	EPSD	TCGA;ICGC;COSMIC	18.469	Loss
Other_TTK_TTK_ST	Q6IBW4	NCAPH2	P33981	TTK	S200	P201S	201	Missense	proximal	1	no	19.983	19.996	EPSD	TCGA;ICGC;COSMIC	18.469	Up-regulation
Other_TTK_TTK_ST	Q6IBW4	NCAPH2	P33981	TTK	S200	P204S	204	Missense	distal	4	no	19.983	21.045	EPSD	TCGA;ICGC;COSMIC	18.469	Up-regulation
Other_TTK_TTK_ST	Q6IBW4	NCAPH2	P33981	TTK	S200	V207I	207	Missense	distal	7	no	19.983	19.655	EPSD	TCGA;ICGC;COSMIC	18.469	Down-regulation
Other_TTK_TTK_ST	Q6IBW4	NCAPH2	P33981	TTK	S200	A205V	205	Missense	distal	5	no	19.983	21.086	EPSD	TCGA;ICGC;COSMIC	18.469	Up-regulation
Other_TTK_TTK_ST	Q6IBW4	NCAPH2	P33981	TTK	T403	K398T	398	Missense	distal	-5	no	23.422	22.782	EPSD	TCGA;ICGC;COSMIC	18.469	Down-regulation
Other_TTK_TTK_ST	Q6IBW4	NCAPH2	P33981	TTK	S428	S428C	428	Missense	central	0	yes	20.449	0.000	EPSD	TCGA;ICGC;COSMIC	18.469	Loss
Other_TTK_TTK_ST	Q6IBW4	NCAPH2	P33981	TTK	S428	E430G	430	Missense	proximal	2	no	20.449	19.134	EPSD	TCGA;ICGC;COSMIC	18.469	Down-regulation
Other_TTK_TTK_ST	Q96E14	RMI2	P33981	TTK	S112	P113L	113	Missense	proximal	1	no	22.096	22.119	PhosphoSitePlus	TCGA;COSMIC	18.469	Up-regulation
AGC_PKC_PKCa_PRKCA_ST	P35367	HRH1	P17252	PRKCA	S94	L99V	99	Missense	distal	5	no	16.736	16.645	EPSD	TCGA;ICGC;COSMIC	16.704	Loss
AGC_PKC_PKCa_PRKCA_ST	P35367	HRH1	P17252	PRKCA	S94	R97H	97	Missense	distal	3	no	16.736	16.024	EPSD	TCGA;ICGC;COSMIC	16.704	Loss
AGC_PKC_PKCa_PRKCA_ST	P35367	HRH1	P17252	PRKCA	S94	G96C	96	Missense	proximal	2	no	16.736	17.631	EPSD	TCGA;ICGC;COSMIC	16.704	Up-regulation
AGC_PKC_PKCa_PRKCA_ST	P35367	HRH1	P17252	PRKCA	T140	R143Q	143	Missense	distal	3	no	16.754	14.301	EPSD	TCGA;ICGC;COSMIC	16.704	Loss
AGC_PKC_PKCa_PRKCA_ST	P35367	HRH1	P17252	PRKCA	T140	R139C	139	Missense	proximal	-1	no	16.754	14.094	EPSD	TCGA;ICGC;COSMIC	16.704	Loss
AGC_PKC_PKCa_PRKCA_ST	P35367	HRH1	P17252	PRKCA	T140	Y138S	138	Missense	proximal	-2	no	16.754	16.180	EPSD	TCGA;ICGC;COSMIC	16.704	Loss
AGC_PKC_PKCa_PRKCA_ST	P35367	HRH1	P17252	PRKCA	T140	A146T	146	Missense	distal	6	no	16.754	16.676	EPSD	TCGA;ICGC;COSMIC	16.704	Loss
AGC_PKC_PKCa_PRKCA_ST	P35367	HRH1	P17252	PRKCA	T142	R143Q	143	Missense	proximal	1	no	17.119	17.002	EPSD	TCGA;ICGC;COSMIC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	P35367	HRH1	P17252	PRKCA	T142	R139C	139	Missense	distal	-3	no	17.119	14.380	EPSD	TCGA;ICGC;COSMIC	16.704	Loss
AGC_PKC_PKCa_PRKCA_ST	P35367	HRH1	P17252	PRKCA	T142	Y138S	138	Missense	distal	-4	no	17.119	17.313	EPSD	TCGA;ICGC;COSMIC	16.704	Up-regulation
AGC_PKC_PKCa_PRKCA_ST	P35367	HRH1	P17252	PRKCA	T142	A146T	146	Missense	distal	4	no	17.119	16.672	EPSD	TCGA;ICGC;COSMIC	16.704	Loss
AGC_PKC_PKCa_PRKCA_ST	P35367	HRH1	P17252	PRKCA	S290	E292K	292	Missense	proximal	2	no	12.192	17.472	EPSD	TCGA;ICGC;COSMIC	16.704	Gain
AGC_PKC_PKCa_PRKCA_ST	P35367	HRH1	P17252	PRKCA	S378	R377S	377	Missense	proximal	-1	no	16.986	16.599	EPSD	TCGA;ICGC;COSMIC	16.704	Loss
AGC_PKC_PKCa_PRKCA_ST	P35367	HRH1	P17252	PRKCA	S378	R377K	377	Missense	proximal	-1	no	16.986	17.043	EPSD	TCGA;ICGC;COSMIC	16.704	Up-regulation
AGC_PKC_PKCa_PRKCA_ST	P35367	HRH1	P17252	PRKCA	S380	R377S	377	Missense	distal	-3	no	17.905	15.035	EPSD	TCGA;ICGC;COSMIC	16.704	Loss
AGC_PKC_PKCa_PRKCA_ST	P35367	HRH1	P17252	PRKCA	S380	R377K	377	Missense	distal	-3	no	17.905	15.879	EPSD	TCGA;ICGC;COSMIC	16.704	Loss
AGC_PKC_PKCa_PRKCA_ST	P35367	HRH1	P17252	PRKCA	S396	S396L	396	Missense	central	0	yes	21.552	0.000	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	16.704	Loss
AGC_PKC_PKCa_PRKCA_ST	P35367	HRH1	P17252	PRKCA	S396	R395H	395	Missense	proximal	-1	no	21.552	21.229	EPSD;PhosphoSitePlus	TCGA;ICGC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	P35367	HRH1	P17252	PRKCA	T478	F479L	479	Missense	proximal	1	no	17.273	16.616	PhosphoSitePlus;EPSD	TCGA;ICGC;COSMIC	16.704	Loss
AGC_PKC_PKCa_PRKCA_ST	P29474	NOS3	P17252	PRKCA	S260	R262Q	262	Missense	proximal	2	no	22.224	18.389	EPSD	TCGA;ICGC;COSMIC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	P29474	NOS3	P17252	PRKCA	S483	K486N	486	Missense	distal	3	no	17.071	16.123	EPSD	TCGA;ICGC;COSMIC	16.704	Loss
AGC_PKC_PKCa_PRKCA_ST	P29474	NOS3	P17252	PRKCA	S483	P479T	479	Missense	distal	-4	no	17.071	16.580	EPSD	TCGA;ICGC;COSMIC	16.704	Loss
AGC_PKC_PKCa_PRKCA_ST	P29474	NOS3	P17252	PRKCA	S483	T488A	488	Missense	distal	5	no	17.071	17.349	EPSD	TCGA;ICGC;COSMIC	16.704	Up-regulation
AGC_PKC_PKCa_PRKCA_ST	P29474	NOS3	P17252	PRKCA	T495	T488A	488	Missense	distal	-7	no	21.488	21.493	PhosphoSitePlus	TCGA;ICGC;COSMIC	16.704	Up-regulation
AGC_PKC_PKCa_PRKCA_ST	P29474	NOS3	P17252	PRKCA	S600	S600F	600	Missense	central	0	yes	18.159	0.000	EPSD	TCGA;ICGC;COSMIC	16.704	Loss
AGC_PKC_PKCa_PRKCA_ST	P29474	NOS3	P17252	PRKCA	S600	P601L	601	Missense	proximal	1	no	18.159	18.586	EPSD	TCGA;ICGC;COSMIC	16.704	Up-regulation
AGC_PKC_PKCa_PRKCA_ST	P29474	NOS3	P17252	PRKCA	S615	R612C	612	Missense	distal	-3	no	18.397	15.658	EPSD	TCGA;ICGC;COSMIC	16.704	Loss
AGC_PKC_PKCa_PRKCA_ST	P29474	NOS3	P17252	PRKCA	S615	S617F	617	Missense	proximal	2	no	18.397	18.714	EPSD	TCGA;ICGC;COSMIC;GDSC	16.704	Up-regulation
AGC_PKC_PKCa_PRKCA_ST	P29474	NOS3	P17252	PRKCA	S615	R612H	612	Missense	distal	-3	no	18.397	14.541	EPSD	TCGA;ICGC;COSMIC	16.704	Loss
AGC_PKC_PKCa_PRKCA_ST	P29474	NOS3	P17252	PRKCA	S633	G640V	640	Missense	distal	7	no	18.170	18.092	EPSD	TCGA;ICGC;COSMIC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	P29474	NOS3	P17252	PRKCA	S725	R721Q	721	Missense	distal	-4	no	17.751	17.374	EPSD	TCGA;ICGC;COSMIC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	P29474	NOS3	P17252	PRKCA	S738	E742Q	742	Missense	distal	4	no	16.757	16.908	EPSD	TCGA;ICGC;COSMIC	16.704	Up-regulation
AGC_PKC_PKCa_PRKCA_ST	P29474	NOS3	P17252	PRKCA	S738	E742K	742	Missense	distal	4	no	16.757	17.296	EPSD	TCGA;ICGC;COSMIC	16.704	Up-regulation
AGC_PKC_PKCa_PRKCA_ST	P09758	TACSTD2	P17252	PRKCA	S142	G139D	139	Missense	distal	-3	no	18.250	16.469	EPSD	TCGA;ICGC;COSMIC	16.704	Loss
AGC_PKC_PKCa_PRKCA_ST	P09758	TACSTD2	P17252	PRKCA	S269	T274I	274	Missense	distal	5	no	17.276	17.258	EPSD	TCGA;ICGC;GDSC;CCLE	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	P09758	TACSTD2	P17252	PRKCA	S303	R301I	301	Missense	proximal	-2	no	21.793	18.205	PhosphoSitePlus	TCGA;ICGC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	P09758	TACSTD2	P17252	PRKCA	S303	S303L	303	Missense	central	0	yes	21.793	0.000	PhosphoSitePlus	TCGA;ICGC	16.704	Loss
AGC_PKC_PKCa_PRKCA_ST	P09758	TACSTD2	P17252	PRKCA	S303	V296A	296	Missense	distal	-7	no	21.793	21.803	PhosphoSitePlus	TCGA;ICGC;COSMIC	16.704	Up-regulation
AGC_PKC_PKCa_PRKCA_ST	Q9BR39	JPH2	P17252	PRKCA	S162	T161M	161	Missense	proximal	-1	no	15.907	16.945	EPSD	TCGA;ICGC	16.704	Gain
AGC_PKC_PKCa_PRKCA_ST	Q9BR39	JPH2	P17252	PRKCA	S165	P158L	158	Missense	distal	-7	no	20.337	20.334	PhosphoSitePlus	TCGA	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	Q9BR39	JPH2	P17252	PRKCA	S165	S164L	164	Missense	proximal	-1	no	20.337	19.918	PhosphoSitePlus	TCGA;ICGC;COSMIC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	Q9BR39	JPH2	P17252	PRKCA	S165	T161M	161	Missense	distal	-4	no	20.337	21.271	PhosphoSitePlus	TCGA;ICGC	16.704	Up-regulation
AGC_PKC_PKCa_PRKCA_ST	Q9BR39	JPH2	P17252	PRKCA	S165	R160C	160	Missense	distal	-5	no	20.337	19.661	PhosphoSitePlus	TCGA;ICGC;COSMIC;CCLE	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	Q9BR39	JPH2	P17252	PRKCA	S235	R236C	236	Missense	proximal	1	no	18.470	15.634	EPSD	TCGA;ICGC;COSMIC	16.704	Loss
AGC_PKC_PKCa_PRKCA_ST	Q9BR39	JPH2	P17252	PRKCA	S238	R236C	236	Missense	proximal	-2	no	17.579	15.879	EPSD	TCGA;ICGC;COSMIC	16.704	Loss
AGC_PKC_PKCa_PRKCA_ST	Q9BR39	JPH2	P17252	PRKCA	S241	R236C	236	Missense	distal	-5	no	20.964	20.288	EPSD	TCGA;ICGC;COSMIC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	Q9BR39	JPH2	P17252	PRKCA	S241	V246F	246	Missense	distal	5	no	20.964	21.279	EPSD	TCGA;ICGC;COSMIC	16.704	Up-regulation
AGC_PKC_PKCa_PRKCA_ST	Q9BR39	JPH2	P17252	PRKCA	S244	V246F	246	Missense	proximal	2	no	17.352	18.063	EPSD	TCGA;ICGC;COSMIC	16.704	Up-regulation
AGC_PKC_PKCa_PRKCA_ST	Q9BR39	JPH2	P17252	PRKCA	S247	V246F	246	Missense	proximal	-1	no	17.992	18.747	EPSD	TCGA;ICGC;COSMIC	16.704	Up-regulation
AGC_PKC_PKCa_PRKCA_ST	Q9BR39	JPH2	P17252	PRKCA	S306	E307K	307	Missense	proximal	1	no	18.147	19.751	EPSD	TCGA;ICGC;COSMIC;GDSC;CCLE	16.704	Up-regulation
AGC_PKC_PKCa_PRKCA_ST	Q9BR39	JPH2	P17252	PRKCA	S306	R308C	308	Missense	proximal	2	no	18.147	13.796	EPSD	TCGA;ICGC;COSMIC	16.704	Loss
AGC_PKC_PKCa_PRKCA_ST	Q9BR39	JPH2	P17252	PRKCA	S306	S310G	310	Missense	distal	4	no	18.147	17.789	EPSD	TCGA;ICGC;COSMIC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	Q9BR39	JPH2	P17252	PRKCA	S306	L312H	312	Missense	distal	6	no	18.147	18.152	EPSD	TCGA;ICGC;COSMIC	16.704	Up-regulation
AGC_PKC_PKCa_PRKCA_ST	Q9BR39	JPH2	P17252	PRKCA	S306	L312I	312	Missense	distal	6	no	18.147	18.123	EPSD	TCGA;ICGC;COSMIC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	Q9BR39	JPH2	P17252	PRKCA	S306	G302S	302	Missense	distal	-4	no	18.147	18.055	EPSD	TCGA;ICGC;COSMIC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	Q9BR39	JPH2	P17252	PRKCA	S306	R313H	313	Missense	distal	7	no	18.147	18.075	EPSD	TCGA;ICGC;COSMIC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	Q9BR39	JPH2	P17252	PRKCA	S306	R308H	308	Missense	proximal	2	no	18.147	13.123	EPSD	TCGA;ICGC;COSMIC	16.704	Loss
AGC_PKC_PKCa_PRKCA_ST	Q9BR39	JPH2	P17252	PRKCA	S306	S301L	301	Missense	distal	-5	no	18.147	18.446	EPSD	TCGA;ICGC;COSMIC	16.704	Up-regulation
AGC_PKC_PKCa_PRKCA_ST	Q9BR39	JPH2	P17252	PRKCA	S306	R300C	300	Missense	distal	-6	no	18.147	17.777	EPSD	TCGA	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	Q9BR39	JPH2	P17252	PRKCA	S310	E307K	307	Missense	distal	-3	no	15.665	18.577	EPSD	TCGA;ICGC;COSMIC;GDSC;CCLE	16.704	Gain
AGC_PKC_PKCa_PRKCA_ST	Q9BR39	JPH2	P17252	PRKCA	S359	R352L	352	Missense	distal	-7	no	19.136	19.125	EPSD	TCGA;ICGC;COSMIC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	Q9BR39	JPH2	P17252	PRKCA	S359	R353H	353	Missense	distal	-6	no	19.136	19.068	EPSD	TCGA;ICGC;COSMIC;GDSC;CCLE	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	Q9BR39	JPH2	P17252	PRKCA	S359	S359N	359	Missense	central	0	yes	19.136	0.000	EPSD	TCGA;ICGC;COSMIC	16.704	Loss
AGC_PKC_PKCa_PRKCA_ST	Q9BR39	JPH2	P17252	PRKCA	S534	R537C	537	Missense	distal	3	no	19.046	16.428	EPSD	TCGA;ICGC;COSMIC	16.704	Loss
AGC_PKC_PKCa_PRKCA_ST	Q9BR39	JPH2	P17252	PRKCA	T540	R537C	537	Missense	distal	-3	no	18.930	16.191	EPSD	TCGA;ICGC;COSMIC	16.704	Loss
AGC_PKC_PKCa_PRKCA_ST	P29966	MARCKS	P17252	PRKCA	T8	E13Q	13	Missense	distal	5	no	17.088	17.349	EPSD	TCGA;ICGC;COSMIC	16.704	Up-regulation
AGC_PKC_PKCa_PRKCA_ST	P29966	MARCKS	P17252	PRKCA	S27	P28L	28	Missense	proximal	1	no	16.362	16.789	EPSD	TCGA;ICGC;COSMIC	16.704	Gain
AGC_PKC_PKCa_PRKCA_ST	P29966	MARCKS	P17252	PRKCA	S163	S167C	167	Missense	distal	4	no	23.529	22.374	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	P29966	MARCKS	P17252	PRKCA	S170	S167C	167	Missense	distal	-3	no	21.726	21.856	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	16.704	Up-regulation
AGC_PKC_PKCa_PRKCA_ST	P11387	TOP1	P17252	PRKCA	S10	E13K	13	Missense	distal	3	no	16.840	17.456	EPSD	TCGA;ICGC;COSMIC	16.704	Up-regulation
AGC_PKC_PKCa_PRKCA_ST	P11387	TOP1	P17252	PRKCA	S21	S21C	21	Missense	central	0	yes	19.040	0.000	PhosphoSitePlus	TCGA;ICGC;COSMIC;CCLE	16.704	Loss
AGC_PKC_PKCa_PRKCA_ST	P11387	TOP1	P17252	PRKCA	S57	E53G	53	Missense	distal	-4	no	18.319	18.913	EPSD	TCGA;ICGC;COSMIC	16.704	Up-regulation
AGC_PKC_PKCa_PRKCA_ST	P11387	TOP1	P17252	PRKCA	S57	H61Q	61	Missense	distal	4	no	18.319	18.384	EPSD	TCGA;ICGC;COSMIC	16.704	Up-regulation
AGC_PKC_PKCa_PRKCA_ST	P11387	TOP1	P17252	PRKCA	S74	D71Y	71	Missense	distal	-3	no	17.158	17.640	EPSD	TCGA;COSMIC	16.704	Up-regulation
AGC_PKC_PKCa_PRKCA_ST	P11387	TOP1	P17252	PRKCA	S74	G72E	72	Missense	proximal	-2	no	17.158	15.904	EPSD	TCGA;ICGC;COSMIC	16.704	Loss
AGC_PKC_PKCa_PRKCA_ST	P11387	TOP1	P17252	PRKCA	S423	Y426C	426	Missense	distal	3	no	17.718	17.368	EPSD	TCGA;ICGC;COSMIC;GDSC;CCLE	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	P11387	TOP1	P17252	PRKCA	S432	E438K	438	Missense	distal	6	no	16.651	16.745	EPSD	TCGA;ICGC;COSMIC	16.704	Gain
AGC_PKC_PKCa_PRKCA_ST	P11387	TOP1	P17252	PRKCA	S506	R508C	508	Missense	proximal	2	no	18.819	14.468	EPSD	TCGA;ICGC;COSMIC	16.704	Loss
AGC_PKC_PKCa_PRKCA_ST	P11387	TOP1	P17252	PRKCA	S506	T501I	501	Missense	distal	-5	no	18.819	18.346	EPSD	TCGA;ICGC;COSMIC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	P11387	TOP1	P17252	PRKCA	S534	D528Y	528	Missense	distal	-6	no	20.451	20.482	EPSD	TCGA;ICGC;COSMIC	16.704	Up-regulation
AGC_PKC_PKCa_PRKCA_ST	P11387	TOP1	P17252	PRKCA	S643	E641Q	641	Missense	proximal	-2	no	14.777	17.144	EPSD	TCGA;ICGC;COSMIC	16.704	Gain
AGC_PKC_PKCa_PRKCA_ST	P11387	TOP1	P17252	PRKCA	S686	K687N	687	Missense	proximal	1	no	19.270	18.106	EPSD	TCGA;ICGC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	P11387	TOP1	P17252	PRKCA	S686	Q692E	692	Missense	distal	6	no	19.270	19.287	EPSD	TCGA;ICGC;COSMIC	16.704	Up-regulation
AGC_PKC_PKCa_PRKCA_ST	Q96PH1	NOX5	P17252	PRKCA	S521	R517M	517	Missense	distal	-4	no	18.900	18.979	EPSD	TCGA;ICGC	16.704	Up-regulation
AGC_PKC_PKCa_PRKCA_ST	Q96PH1	NOX5	P17252	PRKCA	S536	G531A	531	Missense	distal	-5	no	18.737	18.547	EPSD	TCGA;ICGC;COSMIC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	Q96PH1	NOX5	P17252	PRKCA	S536	R542T	542	Missense	distal	6	no	18.737	18.617	EPSD	TCGA;COSMIC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	Q96PH1	NOX5	P17252	PRKCA	S536	R530C	530	Missense	distal	-6	no	18.737	18.368	EPSD	TCGA;ICGC;COSMIC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	Q96PH1	NOX5	P17252	PRKCA	S536	G529C	529	Missense	distal	-7	no	18.737	18.727	EPSD	TCGA;COSMIC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	Q96PH1	NOX5	P17252	PRKCA	S536	K543N	543	Missense	distal	7	no	18.737	18.617	EPSD	TCGA;ICGC;COSMIC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	Q96PH1	NOX5	P17252	PRKCA	T540	R542T	542	Missense	proximal	2	no	18.316	13.506	EPSD	TCGA;COSMIC	16.704	Loss
AGC_PKC_PKCa_PRKCA_ST	Q96PH1	NOX5	P17252	PRKCA	T540	K543N	543	Missense	distal	3	no	18.316	17.369	EPSD	TCGA;ICGC;COSMIC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	Q96PH1	NOX5	P17252	PRKCA	S544	R542T	542	Missense	proximal	-2	no	22.733	19.839	EPSD	TCGA;COSMIC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	Q96PH1	NOX5	P17252	PRKCA	S544	S551Y	551	Missense	distal	7	no	22.733	22.727	EPSD	TCGA;COSMIC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	Q96PH1	NOX5	P17252	PRKCA	S544	G550S	550	Missense	distal	6	no	22.733	22.811	EPSD	TCGA;COSMIC	16.704	Up-regulation
AGC_PKC_PKCa_PRKCA_ST	Q96PH1	NOX5	P17252	PRKCA	S544	K543N	543	Missense	proximal	-1	no	22.733	22.131	EPSD	TCGA;ICGC;COSMIC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	Q96PH1	NOX5	P17252	PRKCA	S548	R542T	542	Missense	distal	-6	no	18.034	17.835	EPSD	TCGA;COSMIC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	Q96PH1	NOX5	P17252	PRKCA	S548	S551Y	551	Missense	distal	3	no	18.034	17.158	EPSD	TCGA;COSMIC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	Q96PH1	NOX5	P17252	PRKCA	S548	G550S	550	Missense	proximal	2	no	18.034	18.660	EPSD	TCGA;COSMIC	16.704	Up-regulation
AGC_PKC_PKCa_PRKCA_ST	Q96PH1	NOX5	P17252	PRKCA	S548	K543N	543	Missense	distal	-5	no	18.034	17.691	EPSD	TCGA;ICGC;COSMIC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	Q96PH1	NOX5	P17252	PRKCA	S705	T707M	707	Missense	proximal	2	no	17.000	17.363	EPSD	TCGA;COSMIC	16.704	Up-regulation
AGC_PKC_PKCa_PRKCA_ST	Q96PH1	NOX5	P17252	PRKCA	S705	R712C	712	Missense	distal	7	no	17.000	16.777	EPSD	TCGA;COSMIC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	P37802	TAGLN2	P17252	PRKCA	T180	G183R	183	Missense	distal	3	no	16.654	17.294	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	16.704	Gain
AGC_PKC_PKCa_PRKCA_ST	P37802	TAGLN2	P17252	PRKCA	T180	G175R	175	Missense	distal	-5	no	16.654	16.945	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	16.704	Gain
AGC_PKC_PKCa_PRKCA_ST	P37802	TAGLN2	P17252	PRKCA	S185	G183R	183	Missense	proximal	-2	no	16.440	19.312	PhosphoSitePlus;EPSD	TCGA;ICGC;COSMIC	16.704	Gain
AGC_PKC_PKCa_PRKCA_ST	Q15080	NCF4	P17252	PRKCA	T154	R153C	153	Missense	proximal	-1	no	20.732	18.072	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	Q15080	NCF4	P17252	PRKCA	S159	R153C	153	Missense	distal	-6	no	16.862	16.492	EPSD	TCGA;ICGC;COSMIC	16.704	Loss
AGC_PKC_PKCa_PRKCA_ST	Q15080	NCF4	P17252	PRKCA	S159	G164D	164	Missense	distal	5	no	16.862	16.781	EPSD	TCGA;ICGC;COSMIC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	P04083	ANXA1	P17252	PRKCA	T24	S27L	27	Missense	distal	3	no	18.465	17.618	EPSD	TCGA;ICGC;COSMIC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	P04083	ANXA1	P17252	PRKCA	T24	E17K	17	Missense	distal	-7	no	18.465	18.473	EPSD	TCGA;ICGC;COSMIC	16.704	Up-regulation
AGC_PKC_PKCa_PRKCA_ST	P04083	ANXA1	P17252	PRKCA	T24	K29N	29	Missense	distal	5	no	18.465	17.959	EPSD	TCGA;ICGC;COSMIC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	P04083	ANXA1	P17252	PRKCA	S27	P32A	32	Missense	distal	5	no	20.046	19.989	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	P04083	ANXA1	P17252	PRKCA	S27	S27L	27	Missense	central	0	yes	20.046	0.000	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	16.704	Loss
AGC_PKC_PKCa_PRKCA_ST	P04083	ANXA1	P17252	PRKCA	S27	K29N	29	Missense	proximal	2	no	20.046	15.097	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	16.704	Loss
AGC_PKC_PKCa_PRKCA_ST	P04083	ANXA1	P17252	PRKCA	S28	P32A	32	Missense	distal	4	no	17.015	17.231	PhosphoSitePlus;EPSD	TCGA;ICGC;COSMIC	16.704	Up-regulation
AGC_PKC_PKCa_PRKCA_ST	P04083	ANXA1	P17252	PRKCA	S28	S27L	27	Missense	proximal	-1	no	17.015	16.595	PhosphoSitePlus;EPSD	TCGA;ICGC;COSMIC	16.704	Loss
AGC_PKC_PKCa_PRKCA_ST	P04083	ANXA1	P17252	PRKCA	S28	A35V	35	Missense	distal	7	no	17.015	16.960	PhosphoSitePlus;EPSD	TCGA;ICGC;COSMIC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	P04083	ANXA1	P17252	PRKCA	S28	K29N	29	Missense	proximal	1	no	17.015	15.850	PhosphoSitePlus;EPSD	TCGA;ICGC;COSMIC	16.704	Loss
AGC_PKC_PKCa_PRKCA_ST	P16144	ITGB4	P17252	PRKCA	S7	S7R	7	Missense	central	0	yes	18.162	0.000	EPSD	TCGA;ICGC;COSMIC	16.704	Loss
AGC_PKC_PKCa_PRKCA_ST	P16144	ITGB4	P17252	PRKCA	S7	R5H	5	Missense	proximal	-2	no	18.162	13.609	EPSD	TCGA;ICGC;COSMIC	16.704	Loss
AGC_PKC_PKCa_PRKCA_ST	P16144	ITGB4	P17252	PRKCA	S377	G380S	380	Missense	distal	3	no	17.475	16.724	EPSD	TCGA;ICGC;COSMIC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	P16144	ITGB4	P17252	PRKCA	S377	R382Q	382	Missense	distal	5	no	17.475	17.467	EPSD	TCGA;ICGC;COSMIC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	P16144	ITGB4	P17252	PRKCA	S377	D376G	376	Missense	proximal	-1	no	17.475	18.219	EPSD	TCGA;ICGC;COSMIC	16.704	Up-regulation
AGC_PKC_PKCa_PRKCA_ST	P16144	ITGB4	P17252	PRKCA	S377	R382W	382	Missense	distal	5	no	17.475	16.967	EPSD	TCGA;ICGC;COSMIC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	P16144	ITGB4	P17252	PRKCA	S377	R373W	373	Missense	distal	-4	no	17.475	16.649	EPSD	TCGA;ICGC;COSMIC	16.704	Loss
AGC_PKC_PKCa_PRKCA_ST	P16144	ITGB4	P17252	PRKCA	S397	S397F	397	Missense	central	0	yes	17.492	0.000	EPSD	TCGA;ICGC;COSMIC	16.704	Loss
AGC_PKC_PKCa_PRKCA_ST	P16144	ITGB4	P17252	PRKCA	S771	H773R	773	Missense	proximal	2	no	12.543	17.566	EPSD	TCGA;ICGC;COSMIC	16.704	Gain
AGC_PKC_PKCa_PRKCA_ST	P16144	ITGB4	P17252	PRKCA	S821	R823C	823	Missense	proximal	2	no	17.361	13.010	EPSD	TCGA;ICGC	16.704	Loss
AGC_PKC_PKCa_PRKCA_ST	P16144	ITGB4	P17252	PRKCA	S1114	M1116K	1116	Missense	proximal	2	no	14.464	18.491	EPSD	TCGA;ICGC;COSMIC	16.704	Gain
AGC_PKC_PKCa_PRKCA_ST	P16144	ITGB4	P17252	PRKCA	S1118	M1116K	1116	Missense	proximal	-2	no	17.040	17.394	EPSD	TCGA;ICGC;COSMIC	16.704	Up-regulation
AGC_PKC_PKCa_PRKCA_ST	P16144	ITGB4	P17252	PRKCA	S1119	M1116K	1116	Missense	distal	-3	no	15.784	16.730	EPSD	TCGA;ICGC;COSMIC	16.704	Gain
AGC_PKC_PKCa_PRKCA_ST	P16144	ITGB4	P17252	PRKCA	T1297	R1301H	1301	Missense	distal	4	no	18.072	17.790	EPSD	TCGA;ICGC;COSMIC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	P16144	ITGB4	P17252	PRKCA	S1325	R1322G	1322	Missense	distal	-3	no	16.878	13.616	EPSD	TCGA;ICGC	16.704	Loss
AGC_PKC_PKCa_PRKCA_ST	P16144	ITGB4	P17252	PRKCA	S1360	R1355C	1355	Missense	distal	-5	no	18.940	18.264	PhosphoSitePlus;EPSD	TCGA;ICGC;COSMIC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	P16144	ITGB4	P17252	PRKCA	S1360	G1359S	1359	Missense	proximal	-1	no	18.940	18.692	PhosphoSitePlus;EPSD	TCGA;ICGC;COSMIC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	P16144	ITGB4	P17252	PRKCA	S1360	S1358L	1358	Missense	proximal	-2	no	18.940	19.554	PhosphoSitePlus;EPSD	TCGA;ICGC;COSMIC	16.704	Up-regulation
AGC_PKC_PKCa_PRKCA_ST	P16144	ITGB4	P17252	PRKCA	S1360	R1362K	1362	Missense	proximal	2	no	18.940	18.518	PhosphoSitePlus;EPSD	TCGA;ICGC;COSMIC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	P16144	ITGB4	P17252	PRKCA	S1364	G1359S	1359	Missense	distal	-5	no	18.268	18.132	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	P16144	ITGB4	P17252	PRKCA	S1364	S1358L	1358	Missense	distal	-6	no	18.268	18.203	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	P16144	ITGB4	P17252	PRKCA	S1364	R1362K	1362	Missense	proximal	-2	no	18.268	16.641	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	16.704	Loss
AGC_PKC_PKCa_PRKCA_ST	P16144	ITGB4	P17252	PRKCA	S1364	T1369I	1369	Missense	distal	5	no	18.268	18.250	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	P16144	ITGB4	P17252	PRKCA	S1511	D1509Y	1509	Missense	proximal	-2	no	16.014	16.704	EPSD	TCGA;COSMIC	16.704	Gain
AGC_PKC_PKCa_PRKCA_ST	P16144	ITGB4	P17252	PRKCA	S1747	A1749G	1749	Missense	proximal	2	no	17.243	16.696	EPSD	TCGA;COSMIC	16.704	Loss
AGC_PKC_PKCa_PRKCA_ST	P16144	ITGB4	P17252	PRKCA	S1747	R1748H	1748	Missense	proximal	1	no	17.243	16.430	EPSD	TCGA;COSMIC	16.704	Loss
AGC_PKC_PKCa_PRKCA_ST	P16144	ITGB4	P17252	PRKCA	S1747	P1743L	1743	Missense	distal	-4	no	17.243	16.983	EPSD	TCGA	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	P08684	CYP3A4	P17252	PRKCA	S131	S131L	131	Missense	central	0	yes	19.379	0.000	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	16.704	Loss
AGC_PKC_PKCa_PRKCA_ST	P08684	CYP3A4	P17252	PRKCA	S131	S134Y	134	Missense	distal	3	no	19.379	18.503	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	P08684	CYP3A4	P17252	PRKCA	S131	E125K	125	Missense	distal	-6	no	19.379	19.447	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	16.704	Up-regulation
AGC_PKC_PKCa_PRKCA_ST	P08684	CYP3A4	P17252	PRKCA	S131	E125D	125	Missense	distal	-6	no	19.379	19.296	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	P08684	CYP3A4	P17252	PRKCA	S259	E262K	262	Missense	distal	3	no	17.083	17.699	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	16.704	Up-regulation
AGC_PKC_PKCa_PRKCA_ST	P08684	CYP3A4	P17252	PRKCA	S259	R260C	260	Missense	proximal	1	no	17.083	14.247	EPSD;PhosphoSitePlus	TCGA;COSMIC	16.704	Loss
AGC_PKC_PKCa_PRKCA_ST	P08684	CYP3A4	P17252	PRKCA	T264	E262K	262	Missense	proximal	-2	no	16.001	18.500	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	16.704	Gain
AGC_PKC_PKCa_PRKCA_ST	P08684	CYP3A4	P17252	PRKCA	S420	E417Q	417	Missense	distal	-3	no	20.156	22.237	EPSD;PhosphoSitePlus	TCGA;COSMIC	16.704	Up-regulation
AGC_PKC_PKCa_PRKCA_ST	P08684	CYP3A4	P17252	PRKCA	S420	D425E	425	Missense	distal	5	no	20.156	20.248	EPSD;PhosphoSitePlus	TCGA;COSMIC	16.704	Up-regulation
AGC_PKC_PKCa_PRKCA_ST	P08684	CYP3A4	P17252	PRKCA	S420	N426S	426	Missense	distal	6	no	20.156	20.258	EPSD;PhosphoSitePlus	TCGA;COSMIC	16.704	Up-regulation
AGC_PKC_PKCa_PRKCA_ST	P18031	PTPN1	P17252	PRKCA	S378	V375L	375	Missense	distal	-3	no	21.090	20.424	PhosphoSitePlus	TCGA;COSMIC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	P24844	MYL9	P17252	PRKCA	S2	K7R	7	Missense	distal	5	no	23.201	23.057	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	P24844	MYL9	P17252	PRKCA	S2	A6V	6	Missense	distal	4	no	23.201	21.863	EPSD;PhosphoSitePlus	TCGA;ICGC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	P24844	MYL9	P17252	PRKCA	S3	K7R	7	Missense	distal	4	no	21.575	21.404	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	P24844	MYL9	P17252	PRKCA	S3	A6V	6	Missense	distal	3	no	21.575	21.319	EPSD;PhosphoSitePlus	TCGA;ICGC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	P24844	MYL9	P17252	PRKCA	T10	K7R	7	Missense	distal	-3	no	22.937	24.963	PhosphoSitePlus;EPSD	TCGA;ICGC;COSMIC	16.704	Up-regulation
AGC_PKC_PKCa_PRKCA_ST	P24844	MYL9	P17252	PRKCA	T10	T11I	11	Missense	proximal	1	no	22.937	24.273	PhosphoSitePlus;EPSD	TCGA;ICGC;COSMIC	16.704	Up-regulation
AGC_PKC_PKCa_PRKCA_ST	P24844	MYL9	P17252	PRKCA	T10	R17W	17	Missense	distal	7	no	22.937	22.757	PhosphoSitePlus;EPSD	TCGA;ICGC;COSMIC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	P24844	MYL9	P17252	PRKCA	T10	A6V	6	Missense	distal	-4	no	22.937	22.378	PhosphoSitePlus;EPSD	TCGA;ICGC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	P24844	MYL9	P17252	PRKCA	T10	T11S	11	Missense	proximal	1	no	22.937	22.610	PhosphoSitePlus;EPSD	TCGA;ICGC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	P24844	MYL9	P17252	PRKCA	T11	K7R	7	Missense	distal	-4	no	20.429	20.394	EPSD	TCGA;ICGC;COSMIC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	P24844	MYL9	P17252	PRKCA	T11	T11I	11	Missense	central	0	yes	20.429	0.000	EPSD	TCGA;ICGC;COSMIC	16.704	Loss
AGC_PKC_PKCa_PRKCA_ST	P24844	MYL9	P17252	PRKCA	T11	R17W	17	Missense	distal	6	no	20.429	20.181	EPSD	TCGA;ICGC;COSMIC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	P24844	MYL9	P17252	PRKCA	T11	A6V	6	Missense	distal	-5	no	20.429	20.345	EPSD	TCGA;ICGC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	P24844	MYL9	P17252	PRKCA	S20	R17W	17	Missense	distal	-3	no	17.126	14.772	EPSD	TCGA;ICGC;COSMIC	16.704	Loss
AGC_PKC_PKCa_PRKCA_ST	P19174	PLCG1	P17252	PRKCA	S489	I486M	486	Missense	distal	-3	no	15.850	17.365	EPSD	TCGA;ICGC;COSMIC	16.704	Gain
AGC_PKC_PKCa_PRKCA_ST	P19174	PLCG1	P17252	PRKCA	S981	S982F	982	Missense	proximal	1	no	15.973	17.457	EPSD	TCGA;ICGC;COSMIC	16.704	Gain
AGC_PKC_PKCa_PRKCA_ST	P10636	MAPT	P17252	PRKCA	S171	R168H	168	Missense	distal	-3	no	19.508	15.652	EPSD	TCGA;ICGC;COSMIC	16.704	Loss
AGC_PKC_PKCa_PRKCA_ST	P10636	MAPT	P17252	PRKCA	S171	R168C	168	Missense	distal	-3	no	19.508	16.769	EPSD	TCGA;ICGC;COSMIC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	P10636	MAPT	P17252	PRKCA	S341	G339R	339	Missense	proximal	-2	no	14.626	17.498	EPSD	TCGA;ICGC;COSMIC	16.704	Gain
AGC_PKC_PKCa_PRKCA_ST	P10636	MAPT	P17252	PRKCA	S411	P415L	415	Missense	distal	4	no	18.586	17.994	EPSD	TCGA;ICGC;COSMIC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	P10636	MAPT	P17252	PRKCA	S447	K440E	440	Missense	distal	-7	no	17.139	17.131	EPSD	TCGA;ICGC;COSMIC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	P10636	MAPT	P17252	PRKCA	S447	S452C	452	Missense	distal	5	no	17.139	16.549	EPSD	TCGA;ICGC;COSMIC	16.704	Loss
AGC_PKC_PKCa_PRKCA_ST	P10636	MAPT	P17252	PRKCA	S447	S443F	443	Missense	distal	-4	no	17.139	17.081	EPSD	TCGA;ICGC;COSMIC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	P10636	MAPT	P17252	PRKCA	S447	S444F	444	Missense	distal	-3	no	17.139	17.388	EPSD	TCGA;ICGC	16.704	Up-regulation
AGC_PKC_PKCa_PRKCA_ST	P10636	MAPT	P17252	PRKCA	S447	S452Y	452	Missense	distal	5	no	17.139	17.166	EPSD	TCGA;ICGC;COSMIC	16.704	Up-regulation
AGC_PKC_PKCa_PRKCA_ST	P10636	MAPT	P17252	PRKCA	S451	E456K	456	Missense	distal	5	no	16.679	17.093	EPSD	TCGA;ICGC;COSMIC	16.704	Gain
AGC_PKC_PKCa_PRKCA_ST	P10636	MAPT	P17252	PRKCA	S451	S452Y	452	Missense	proximal	1	no	16.679	17.490	EPSD	TCGA;ICGC;COSMIC	16.704	Gain
AGC_PKC_PKCa_PRKCA_ST	P10636	MAPT	P17252	PRKCA	T470	R472Q	472	Missense	proximal	2	no	16.965	13.131	EPSD	TCGA	16.704	Loss
AGC_PKC_PKCa_PRKCA_ST	P10636	MAPT	P17252	PRKCA	T470	R472W	472	Missense	proximal	2	no	16.965	11.525	EPSD	TCGA;COSMIC	16.704	Loss
AGC_PKC_PKCa_PRKCA_ST	O75689	ADAP1	P17252	PRKCA	S204	D202N	202	Missense	proximal	-2	no	16.922	17.144	EPSD	TCGA;ICGC;COSMIC	16.704	Up-regulation
AGC_PKC_PKCa_PRKCA_ST	O75689	ADAP1	P17252	PRKCA	S204	N203S	203	Missense	proximal	-1	no	16.922	17.080	EPSD	TCGA;COSMIC	16.704	Up-regulation
AGC_PKC_PKCa_PRKCA_ST	P31645	SLC6A4	P17252	PRKCA	S13	S13L	13	Missense	central	0	yes	18.065	0.000	EPSD	TCGA;ICGC;COSMIC	16.704	Loss
AGC_PKC_PKCa_PRKCA_ST	P31645	SLC6A4	P17252	PRKCA	S13	Q9E	9	Missense	distal	-4	no	18.065	17.746	EPSD	TCGA;ICGC;COSMIC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	P31645	SLC6A4	P17252	PRKCA	S13	S8Y	8	Missense	distal	-5	no	18.065	17.983	EPSD	TCGA;ICGC;COSMIC;GDSC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	P31645	SLC6A4	P17252	PRKCA	S149	G146R	146	Missense	distal	-3	no	16.272	19.534	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	16.704	Gain
AGC_PKC_PKCa_PRKCA_ST	P31645	SLC6A4	P17252	PRKCA	S277	S277Y	277	Missense	central	0	yes	17.966	0.000	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	16.704	Loss
AGC_PKC_PKCa_PRKCA_ST	P31645	SLC6A4	P17252	PRKCA	S277	V280A	280	Missense	distal	3	no	17.966	18.222	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	16.704	Up-regulation
AGC_PKC_PKCa_PRKCA_ST	P31645	SLC6A4	P17252	PRKCA	S277	K275N	275	Missense	proximal	-2	no	17.966	16.397	EPSD;PhosphoSitePlus	TCGA;ICGC	16.704	Loss
AGC_PKC_PKCa_PRKCA_ST	P31645	SLC6A4	P17252	PRKCA	T603	P601L	601	Missense	proximal	-2	no	16.633	16.987	PhosphoSitePlus;EPSD	TCGA;ICGC;COSMIC	16.704	Gain
AGC_PKC_PKCa_PRKCA_ST	P05107	ITGB2	P17252	PRKCA	T118	A112S	112	Missense	distal	-6	no	19.005	19.042	EPSD	TCGA;ICGC;COSMIC	16.704	Up-regulation
AGC_PKC_PKCa_PRKCA_ST	P05107	ITGB2	P17252	PRKCA	T118	R121Q	121	Missense	distal	3	no	19.005	16.552	EPSD	TCGA;ICGC;COSMIC	16.704	Loss
AGC_PKC_PKCa_PRKCA_ST	P05107	ITGB2	P17252	PRKCA	T118	R121W	121	Missense	distal	3	no	19.005	16.072	EPSD	TCGA;ICGC;COSMIC	16.704	Loss
AGC_PKC_PKCa_PRKCA_ST	P05107	ITGB2	P17252	PRKCA	T118	R120W	120	Missense	proximal	2	no	19.005	13.565	EPSD	TCGA;ICGC	16.704	Loss
AGC_PKC_PKCa_PRKCA_ST	P05107	ITGB2	P17252	PRKCA	S490	G495R	495	Missense	distal	5	no	16.585	16.866	EPSD	TCGA;ICGC;COSMIC	16.704	Gain
AGC_PKC_PKCa_PRKCA_ST	P05107	ITGB2	P17252	PRKCA	S496	D500G	500	Missense	distal	4	no	17.597	17.592	EPSD	TCGA;ICGC;COSMIC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	P05107	ITGB2	P17252	PRKCA	S496	R498Q	498	Missense	proximal	2	no	17.597	13.763	EPSD	TCGA;ICGC;COSMIC	16.704	Loss
AGC_PKC_PKCa_PRKCA_ST	P05107	ITGB2	P17252	PRKCA	S496	G495R	495	Missense	proximal	-1	no	17.597	17.736	EPSD	TCGA;ICGC;COSMIC	16.704	Up-regulation
AGC_PKC_PKCa_PRKCA_ST	P19086	GNAZ	P17252	PRKCA	S16	R18I	18	Missense	proximal	2	no	23.083	18.051	PhosphoSitePlus;EPSD	TCGA;ICGC;COSMIC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	P19086	GNAZ	P17252	PRKCA	S16	E9K	9	Missense	distal	-7	no	23.083	23.090	PhosphoSitePlus;EPSD	TCGA;ICGC;COSMIC;GDSC;CCLE	16.704	Up-regulation
AGC_PKC_PKCa_PRKCA_ST	P19086	GNAZ	P17252	PRKCA	S16	R15W	15	Missense	proximal	-1	no	23.083	21.498	PhosphoSitePlus;EPSD	TCGA;ICGC;COSMIC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	P19086	GNAZ	P17252	PRKCA	S16	R17G	17	Missense	proximal	1	no	23.083	22.129	PhosphoSitePlus;EPSD	TCGA;ICGC;COSMIC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	P19086	GNAZ	P17252	PRKCA	S16	K10N	10	Missense	distal	-6	no	23.083	22.959	PhosphoSitePlus;EPSD	TCGA;ICGC;COSMIC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	P19086	GNAZ	P17252	PRKCA	S16	R14Q	14	Missense	proximal	-2	no	23.083	21.324	PhosphoSitePlus;EPSD	TCGA;ICGC;COSMIC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	P19086	GNAZ	P17252	PRKCA	S27	R24P	24	Missense	distal	-3	no	21.195	17.346	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	P19086	GNAZ	P17252	PRKCA	S27	R31H	31	Missense	distal	4	no	21.195	20.912	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	P19086	GNAZ	P17252	PRKCA	S27	R29W	29	Missense	proximal	2	no	21.195	15.755	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	16.704	Loss
AGC_PKC_PKCa_PRKCA_ST	O60941	DTNB	P17252	PRKCA	S497	S497L	497	Missense	central	0	yes	16.796	0.000	EPSD	TCGA;COSMIC	16.704	Loss
AGC_PKC_PKCa_PRKCA_ST	O60941	DTNB	P17252	PRKCA	S497	R495K	495	Missense	proximal	-2	no	16.796	15.169	EPSD	TCGA;COSMIC	16.704	Loss
AGC_PKC_PKCa_PRKCA_ST	O60941	DTNB	P17252	PRKCA	S502	S497L	497	Missense	distal	-5	no	18.707	19.006	EPSD	TCGA;COSMIC	16.704	Up-regulation
AGC_PKC_PKCa_PRKCA_ST	O60941	DTNB	P17252	PRKCA	S502	R495K	495	Missense	distal	-7	no	18.707	18.702	EPSD	TCGA;COSMIC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	O60941	DTNB	P17252	PRKCA	T580	R585H	585	Missense	distal	5	no	17.204	16.944	EPSD	TCGA;ICGC;COSMIC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	O60941	DTNB	P17252	PRKCA	T580	A575T	575	Missense	distal	-5	no	17.204	17.584	EPSD	TCGA;ICGC;COSMIC	16.704	Up-regulation
AGC_PKC_PKCa_PRKCA_ST	O60941	DTNB	P17252	PRKCA	T580	T580M	580	Missense	central	0	yes	17.204	0.000	EPSD	TCGA;ICGC;COSMIC;CCLE	16.704	Loss
AGC_PKC_PKCa_PRKCA_ST	O60941	DTNB	P17252	PRKCA	T580	A577T	577	Missense	distal	-3	no	17.204	17.489	EPSD	TCGA;COSMIC	16.704	Up-regulation
AGC_PKC_PKCa_PRKCA_ST	Q9UKG1	APPL1	P17252	PRKCA	S410	R412Q	412	Missense	proximal	2	no	21.037	17.203	EPSD	TCGA;ICGC;GDSC;CCLE	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	Q9UKG1	APPL1	P17252	PRKCA	S410	E409K	409	Missense	proximal	-1	no	21.037	21.463	EPSD	TCGA;ICGC;COSMIC	16.704	Up-regulation
AGC_PKC_PKCa_PRKCA_ST	Q9UKG1	APPL1	P17252	PRKCA	S410	H408Y	408	Missense	proximal	-2	no	21.037	22.862	EPSD	TCGA;ICGC	16.704	Up-regulation
AGC_PKC_PKCa_PRKCA_ST	Q9UKG1	APPL1	P17252	PRKCA	T422	R424Q	424	Missense	proximal	2	no	18.435	14.601	EPSD	TCGA;ICGC;COSMIC	16.704	Loss
AGC_PKC_PKCa_PRKCA_ST	Q9UKG1	APPL1	P17252	PRKCA	S427	R424Q	424	Missense	distal	-3	no	16.780	13.923	EPSD	TCGA;ICGC;COSMIC	16.704	Loss
AGC_PKC_PKCa_PRKCA_ST	Q9UKG1	APPL1	P17252	PRKCA	S488	K490T	490	Missense	proximal	2	no	18.651	14.262	EPSD	TCGA;ICGC;COSMIC	16.704	Loss
AGC_PKC_PKCa_PRKCA_ST	Q9UKG1	APPL1	P17252	PRKCA	S592	R589W	589	Missense	distal	-3	no	21.410	19.057	EPSD	TCGA;ICGC;COSMIC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	Q9UKG1	APPL1	P17252	PRKCA	S592	V587A	587	Missense	distal	-5	no	21.410	21.494	EPSD	TCGA;ICGC;COSMIC	16.704	Up-regulation
AGC_PKC_PKCa_PRKCA_ST	Q9UKG1	APPL1	P17252	PRKCA	S592	R589Q	589	Missense	distal	-3	no	21.410	18.553	EPSD	TCGA;ICGC;COSMIC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	Q9UKG1	APPL1	P17252	PRKCA	S636	R633C	633	Missense	distal	-3	no	22.058	19.319	EPSD	TCGA;ICGC;COSMIC;CCLE	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	P04626	ERBB2	P17252	PRKCA	T686	R688Q	688	Missense	proximal	2	no	21.608	17.774	PhosphoSitePlus	TCGA;COSMIC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	P04626	ERBB2	P17252	PRKCA	T686	T686M	686	Missense	central	0	yes	21.608	0.000	PhosphoSitePlus	TCGA;COSMIC	16.704	Loss
AGC_PKC_PKCa_PRKCA_ST	P04626	ERBB2	P17252	PRKCA	S760	L755S	755	Missense	distal	-5	no	17.279	16.980	EPSD	TCGA;COSMIC;GDSC;CCLE	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	P04626	ERBB2	P17252	PRKCA	S760	I767M	767	Missense	distal	7	no	17.279	17.443	EPSD	TCGA;COSMIC	16.704	Up-regulation
AGC_PKC_PKCa_PRKCA_ST	P04626	ERBB2	P17252	PRKCA	S760	L755M	755	Missense	distal	-5	no	17.279	17.240	EPSD	TCGA;COSMIC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	P04626	ERBB2	P17252	PRKCA	S760	L755W	755	Missense	distal	-5	no	17.279	17.093	EPSD	TCGA;COSMIC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	P04626	ERBB2	P17252	PRKCA	S760	R756K	756	Missense	distal	-4	no	17.279	17.315	EPSD	TCGA;COSMIC	16.704	Up-regulation
AGC_PKC_PKCa_PRKCA_ST	P04626	ERBB2	P17252	PRKCA	S760	I767F	767	Missense	distal	7	no	17.279	17.369	EPSD	TCGA;COSMIC	16.704	Up-regulation
AGC_PKC_PKCa_PRKCA_ST	P04626	ERBB2	P17252	PRKCA	S819	D821H	821	Missense	proximal	2	no	17.197	17.452	EPSD	TCGA;COSMIC	16.704	Up-regulation
AGC_PKC_PKCa_PRKCA_ST	P04626	ERBB2	P17252	PRKCA	S819	R814H	814	Missense	distal	-5	no	17.197	16.841	EPSD	TCGA;COSMIC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	P04626	ERBB2	P17252	PRKCA	S1050	G1057V	1057	Missense	distal	7	no	16.820	16.742	EPSD	TCGA;COSMIC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	P04626	ERBB2	P17252	PRKCA	S1051	G1057V	1057	Missense	distal	6	no	21.659	21.648	EPSD	TCGA;COSMIC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	P04626	ERBB2	P17252	PRKCA	S1151	R1146Q	1146	Missense	distal	-5	no	19.955	19.803	EPSD	TCGA;COSMIC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	P04626	ERBB2	P17252	PRKCA	T1236	P1233S	1233	Missense	distal	-3	no	16.174	17.153	EPSD	TCGA;COSMIC	16.704	Gain
AGC_PKC_PKCa_PRKCA_ST	O14493	CLDN4	P17252	PRKCA	S194	R201H	201	Missense	distal	7	no	17.231	17.160	PhosphoSitePlus	TCGA;ICGC;COSMIC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	O14493	CLDN4	P17252	PRKCA	S194	S194F	194	Missense	central	0	yes	17.231	0.000	PhosphoSitePlus	TCGA;ICGC;COSMIC	16.704	Loss
AGC_PKC_PKCa_PRKCA_ST	O14493	CLDN4	P17252	PRKCA	S194	R188H	188	Missense	distal	-6	no	17.231	17.163	PhosphoSitePlus	TCGA;ICGC;COSMIC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	P08253	MMP2	P17252	PRKCA	S160	R161Q	161	Missense	proximal	1	no	16.872	16.755	EPSD;PhosphoSitePlus	TCGA;COSMIC;GDSC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	P08253	MMP2	P17252	PRKCA	S160	F159V	159	Missense	proximal	-1	no	16.872	16.117	EPSD;PhosphoSitePlus	TCGA;COSMIC	16.704	Loss
AGC_PKC_PKCa_PRKCA_ST	P08253	MMP2	P17252	PRKCA	S160	R158Q	158	Missense	proximal	-2	no	16.872	15.113	EPSD;PhosphoSitePlus	TCGA;COSMIC	16.704	Loss
AGC_PKC_PKCa_PRKCA_ST	P08253	MMP2	P17252	PRKCA	S160	H163Y	163	Missense	distal	3	no	16.872	15.316	EPSD;PhosphoSitePlus	TCGA;COSMIC	16.704	Loss
AGC_PKC_PKCa_PRKCA_ST	P08253	MMP2	P17252	PRKCA	S160	I162S	162	Missense	proximal	2	no	16.872	17.284	EPSD;PhosphoSitePlus	TCGA	16.704	Up-regulation
AGC_PKC_PKCa_PRKCA_ST	P08253	MMP2	P17252	PRKCA	S160	F159C	159	Missense	proximal	-1	no	16.872	15.307	EPSD;PhosphoSitePlus	TCGA;COSMIC	16.704	Loss
AGC_PKC_PKCa_PRKCA_ST	P08253	MMP2	P17252	PRKCA	T250	R252H	252	Missense	proximal	2	no	17.291	12.267	EPSD;PhosphoSitePlus	TCGA	16.704	Loss
AGC_PKC_PKCa_PRKCA_ST	P08253	MMP2	P17252	PRKCA	S365	K372N	372	Missense	distal	7	no	17.149	17.029	EPSD;PhosphoSitePlus	TCGA;COSMIC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	P08253	MMP2	P17252	PRKCA	S365	R368H	368	Missense	distal	3	no	17.149	16.437	EPSD;PhosphoSitePlus	TCGA;GDSC;CCLE	16.704	Loss
AGC_PKC_PKCa_PRKCA_ST	P08253	MMP2	P17252	PRKCA	S365	A366T	366	Missense	proximal	1	no	17.149	16.678	EPSD;PhosphoSitePlus	TCGA;COSMIC	16.704	Loss
AGC_PKC_PKCa_PRKCA_ST	P08253	MMP2	P17252	PRKCA	T377	T378K	378	Missense	proximal	1	no	16.493	17.377	EPSD;PhosphoSitePlus	TCGA;COSMIC	16.704	Gain
AGC_PKC_PKCa_PRKCA_ST	P21730	C5AR1	P17252	PRKCA	S314	G309D	309	Missense	distal	-5	no	17.842	17.747	PhosphoSitePlus;EPSD	TCGA;ICGC;COSMIC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	P21730	C5AR1	P17252	PRKCA	S314	S314F	314	Missense	central	0	yes	17.842	0.000	PhosphoSitePlus;EPSD	TCGA;ICGC;COSMIC	16.704	Loss
AGC_PKC_PKCa_PRKCA_ST	P21730	C5AR1	P17252	PRKCA	S314	P316S	316	Missense	proximal	2	no	17.842	18.425	PhosphoSitePlus;EPSD	TCGA;ICGC;COSMIC;GDSC;CCLE	16.704	Up-regulation
AGC_PKC_PKCa_PRKCA_ST	P21730	C5AR1	P17252	PRKCA	S314	R320Q	320	Missense	distal	6	no	17.842	17.719	PhosphoSitePlus;EPSD	TCGA;ICGC;COSMIC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	P21730	C5AR1	P17252	PRKCA	S314	L315I	315	Missense	proximal	1	no	17.842	18.678	PhosphoSitePlus;EPSD	TCGA;ICGC;COSMIC	16.704	Up-regulation
AGC_PKC_PKCa_PRKCA_ST	Q9H3Q1	CDC42EP4	P17252	PRKCA	S9	R16C	16	Missense	distal	7	no	17.716	17.493	EPSD	TCGA;ICGC;CCLE	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	Q9H3Q1	CDC42EP4	P17252	PRKCA	S9	L4F	4	Missense	distal	-5	no	17.716	17.520	EPSD	TCGA;ICGC;COSMIC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	Q9H3Q1	CDC42EP4	P17252	PRKCA	S10	R16C	16	Missense	distal	6	no	17.706	17.467	EPSD	TCGA;ICGC;CCLE	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	Q9H3Q1	CDC42EP4	P17252	PRKCA	S10	L4F	4	Missense	distal	-6	no	17.706	17.686	EPSD	TCGA;ICGC;COSMIC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	Q9H3Q1	CDC42EP4	P17252	PRKCA	S11	R16C	16	Missense	distal	5	no	17.583	16.851	EPSD	TCGA;ICGC;CCLE	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	Q9H3Q1	CDC42EP4	P17252	PRKCA	S11	L4F	4	Missense	distal	-7	no	17.583	17.581	EPSD	TCGA;ICGC;COSMIC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	Q9H3Q1	CDC42EP4	P17252	PRKCA	S14	R16C	16	Missense	proximal	2	no	25.078	20.728	EPSD	TCGA;ICGC;CCLE	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	Q9H3Q1	CDC42EP4	P17252	PRKCA	S18	R16C	16	Missense	proximal	-2	no	19.773	18.073	PhosphoSitePlus;EPSD	TCGA;ICGC;CCLE	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	Q9H3Q1	CDC42EP4	P17252	PRKCA	S70	E67K	67	Missense	distal	-3	no	14.201	17.113	EPSD	TCGA;ICGC;COSMIC	16.704	Gain
AGC_PKC_PKCa_PRKCA_ST	Q9H3Q1	CDC42EP4	P17252	PRKCA	S73	E67K	67	Missense	distal	-6	no	20.992	21.060	EPSD	TCGA;ICGC;COSMIC	16.704	Up-regulation
AGC_PKC_PKCa_PRKCA_ST	Q9H3Q1	CDC42EP4	P17252	PRKCA	S73	S77G	77	Missense	distal	4	no	20.992	20.635	EPSD	TCGA;ICGC;COSMIC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	Q9H3Q1	CDC42EP4	P17252	PRKCA	S73	R76H	76	Missense	distal	3	no	20.992	20.280	EPSD	TCGA;ICGC;COSMIC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	Q9H3Q1	CDC42EP4	P17252	PRKCA	S74	E67K	67	Missense	distal	-7	no	19.377	19.384	EPSD	TCGA;ICGC;COSMIC	16.704	Up-regulation
AGC_PKC_PKCa_PRKCA_ST	Q9H3Q1	CDC42EP4	P17252	PRKCA	S74	S77G	77	Missense	distal	3	no	19.377	20.128	EPSD	TCGA;ICGC;COSMIC	16.704	Up-regulation
AGC_PKC_PKCa_PRKCA_ST	Q9H3Q1	CDC42EP4	P17252	PRKCA	S74	R76H	76	Missense	proximal	2	no	19.377	14.353	EPSD	TCGA;ICGC;COSMIC	16.704	Loss
AGC_PKC_PKCa_PRKCA_ST	Q9H3Q1	CDC42EP4	P17252	PRKCA	S77	S77G	77	Missense	central	0	yes	18.331	0.000	EPSD	TCGA;ICGC;COSMIC	16.704	Loss
AGC_PKC_PKCa_PRKCA_ST	Q9H3Q1	CDC42EP4	P17252	PRKCA	S77	R84W	84	Missense	distal	7	no	18.331	18.151	EPSD	TCGA;ICGC;COSMIC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	Q9H3Q1	CDC42EP4	P17252	PRKCA	S77	R76H	76	Missense	proximal	-1	no	18.331	18.008	EPSD	TCGA;ICGC;COSMIC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	Q9H3Q1	CDC42EP4	P17252	PRKCA	S80	S77G	77	Missense	distal	-3	no	20.408	20.016	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	Q9H3Q1	CDC42EP4	P17252	PRKCA	S80	R84W	84	Missense	distal	4	no	20.408	18.872	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	Q9H3Q1	CDC42EP4	P17252	PRKCA	S80	R76H	76	Missense	distal	-4	no	20.408	19.834	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	Q9H3Q1	CDC42EP4	P17252	PRKCA	S89	E96G	96	Missense	distal	7	no	18.491	18.562	EPSD	TCGA;ICGC;COSMIC	16.704	Up-regulation
AGC_PKC_PKCa_PRKCA_ST	Q9H3Q1	CDC42EP4	P17252	PRKCA	S89	S91L	91	Missense	proximal	2	no	18.491	18.124	EPSD	TCGA;ICGC;COSMIC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	Q9H3Q1	CDC42EP4	P17252	PRKCA	S89	R94S	94	Missense	distal	5	no	18.491	18.349	EPSD	TCGA;ICGC;COSMIC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	Q9H3Q1	CDC42EP4	P17252	PRKCA	S89	R84W	84	Missense	distal	-5	no	18.491	18.177	EPSD	TCGA;ICGC;COSMIC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	Q9H3Q1	CDC42EP4	P17252	PRKCA	S91	E96G	96	Missense	distal	5	no	17.474	17.463	EPSD	TCGA;ICGC;COSMIC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	Q9H3Q1	CDC42EP4	P17252	PRKCA	S91	S91L	91	Missense	central	0	yes	17.474	0.000	EPSD	TCGA;ICGC;COSMIC	16.704	Loss
AGC_PKC_PKCa_PRKCA_ST	Q9H3Q1	CDC42EP4	P17252	PRKCA	S91	R94S	94	Missense	distal	3	no	17.474	16.083	EPSD	TCGA;ICGC;COSMIC	16.704	Loss
AGC_PKC_PKCa_PRKCA_ST	Q9H3Q1	CDC42EP4	P17252	PRKCA	S91	R84W	84	Missense	distal	-7	no	17.474	17.458	EPSD	TCGA;ICGC;COSMIC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	Q9H3Q1	CDC42EP4	P17252	PRKCA	S105	S109L	109	Missense	distal	4	no	19.370	18.577	EPSD	TCGA;ICGC;COSMIC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	Q9H3Q1	CDC42EP4	P17252	PRKCA	S295	P291S	291	Missense	distal	-4	no	18.309	18.480	EPSD	TCGA;ICGC;COSMIC	16.704	Up-regulation
AGC_PKC_PKCa_PRKCA_ST	Q9H3Q1	CDC42EP4	P17252	PRKCA	S295	R297L	297	Missense	proximal	2	no	18.309	13.322	EPSD	TCGA;ICGC;COSMIC	16.704	Loss
AGC_PKC_PKCa_PRKCA_ST	Q9H3Q1	CDC42EP4	P17252	PRKCA	S308	S309F	309	Missense	proximal	1	no	15.452	16.936	EPSD	TCGA;ICGC;COSMIC	16.704	Gain
AGC_PKC_PKCa_PRKCA_ST	Q07954	LRP1	P17252	PRKCA	S508	S508C	508	Missense	central	0	yes	18.650	0.000	EPSD	TCGA;ICGC;COSMIC	16.704	Loss
AGC_PKC_PKCa_PRKCA_ST	Q07954	LRP1	P17252	PRKCA	S508	G513D	513	Missense	distal	5	no	18.650	18.569	EPSD	TCGA;ICGC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	Q07954	LRP1	P17252	PRKCA	S508	S511G	511	Missense	distal	3	no	18.650	19.401	EPSD	TCGA;ICGC;COSMIC	16.704	Up-regulation
AGC_PKC_PKCa_PRKCA_ST	Q07954	LRP1	P17252	PRKCA	S508	G509S	509	Missense	proximal	1	no	18.650	18.429	EPSD	TCGA;ICGC;COSMIC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	Q07954	LRP1	P17252	PRKCA	S514	S508C	508	Missense	distal	-6	no	17.600	17.304	EPSD	TCGA;ICGC;COSMIC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	Q07954	LRP1	P17252	PRKCA	S514	G516R	516	Missense	proximal	2	no	17.600	22.845	EPSD	TCGA;ICGC;COSMIC	16.704	Up-regulation
AGC_PKC_PKCa_PRKCA_ST	Q07954	LRP1	P17252	PRKCA	S514	G513D	513	Missense	proximal	-1	no	17.600	16.856	EPSD	TCGA;ICGC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	Q07954	LRP1	P17252	PRKCA	S514	S511G	511	Missense	distal	-3	no	17.600	17.208	EPSD	TCGA;ICGC;COSMIC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	Q07954	LRP1	P17252	PRKCA	S514	G509S	509	Missense	distal	-5	no	17.600	17.463	EPSD	TCGA;ICGC;COSMIC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	Q07954	LRP1	P17252	PRKCA	S1878	G1876D	1876	Missense	proximal	-2	no	17.142	16.596	EPSD	TCGA;ICGC	16.704	Loss
AGC_PKC_PKCa_PRKCA_ST	Q07954	LRP1	P17252	PRKCA	S1878	S1878R	1878	Missense	central	0	yes	17.142	0.000	EPSD	TCGA;ICGC;COSMIC	16.704	Loss
AGC_PKC_PKCa_PRKCA_ST	Q07954	LRP1	P17252	PRKCA	S1997	A1992T	1992	Missense	distal	-5	no	16.987	17.368	EPSD	TCGA;ICGC;COSMIC;GDSC;CCLE	16.704	Up-regulation
AGC_PKC_PKCa_PRKCA_ST	Q07954	LRP1	P17252	PRKCA	S1997	R1993Q	1993	Missense	distal	-4	no	16.987	16.610	EPSD	TCGA	16.704	Loss
AGC_PKC_PKCa_PRKCA_ST	Q07954	LRP1	P17252	PRKCA	S1997	R1999H	1999	Missense	proximal	2	no	16.987	11.963	EPSD	TCGA;ICGC;COSMIC	16.704	Loss
AGC_PKC_PKCa_PRKCA_ST	Q07954	LRP1	P17252	PRKCA	S1997	S1997F	1997	Missense	central	0	yes	16.987	0.000	EPSD	TCGA;ICGC;COSMIC	16.704	Loss
AGC_PKC_PKCa_PRKCA_ST	Q07954	LRP1	P17252	PRKCA	S1997	L1994F	1994	Missense	distal	-3	no	16.987	18.722	EPSD	TCGA;ICGC;COSMIC	16.704	Up-regulation
AGC_PKC_PKCa_PRKCA_ST	Q07954	LRP1	P17252	PRKCA	S2563	K2568N	2568	Missense	distal	5	no	19.367	18.860	EPSD	TCGA;COSMIC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	Q07954	LRP1	P17252	PRKCA	S2563	R2565H	2565	Missense	proximal	2	no	19.367	14.343	EPSD	TCGA;ICGC;COSMIC	16.704	Loss
AGC_PKC_PKCa_PRKCA_ST	Q07954	LRP1	P17252	PRKCA	S2950	R2947C	2947	Missense	distal	-3	no	16.788	14.048	EPSD	TCGA;ICGC;COSMIC;CCLE	16.704	Loss
AGC_PKC_PKCa_PRKCA_ST	Q07954	LRP1	P17252	PRKCA	S3938	R3942Q	3942	Missense	distal	4	no	19.086	18.868	EPSD	TCGA;ICGC;COSMIC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	Q07954	LRP1	P17252	PRKCA	S3938	R3940C	3940	Missense	proximal	2	no	19.086	14.735	EPSD	TCGA;ICGC;COSMIC	16.704	Loss
AGC_PKC_PKCa_PRKCA_ST	Q07954	LRP1	P17252	PRKCA	S3938	A3933V	3933	Missense	distal	-5	no	19.086	19.002	EPSD	TCGA;ICGC;COSMIC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	Q07954	LRP1	P17252	PRKCA	T4034	R4036W	4036	Missense	proximal	2	no	17.363	11.923	EPSD	TCGA;ICGC;COSMIC	16.704	Loss
AGC_PKC_PKCa_PRKCA_ST	Q07954	LRP1	P17252	PRKCA	S4071	A4064S	4064	Missense	distal	-7	no	18.278	18.276	EPSD	TCGA;ICGC;COSMIC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	P52565	ARHGDIA	P17252	PRKCA	S47	D45N	45	Missense	proximal	-2	no	17.169	17.391	EPSD	TCGA;ICGC;COSMIC	16.704	Up-regulation
AGC_PKC_PKCa_PRKCA_ST	P52565	ARHGDIA	P17252	PRKCA	S96	S96R	96	Missense	central	0	yes	20.335	0.000	EPSD;PhosphoSitePlus	TCGA;ICGC	16.704	Loss
AGC_PKC_PKCa_PRKCA_ST	P52565	ARHGDIA	P17252	PRKCA	T132	G136D	136	Missense	distal	4	no	17.698	17.703	EPSD	TCGA;ICGC;COSMIC	16.704	Up-regulation
AGC_PKC_PKCa_PRKCA_ST	P52565	ARHGDIA	P17252	PRKCA	T132	T132A	132	Missense	central	0	yes	17.698	0.000	EPSD	TCGA;ICGC	16.704	Loss
AGC_PKC_PKCa_PRKCA_ST	P52565	ARHGDIA	P17252	PRKCA	T132	T132M	132	Missense	central	0	yes	17.698	0.000	EPSD	TCGA;ICGC;COSMIC	16.704	Loss
AGC_PKC_PKCa_PRKCA_ST	P52565	ARHGDIA	P17252	PRKCA	T132	Y128C	128	Missense	distal	-4	no	17.698	16.741	EPSD	TCGA;ICGC;COSMIC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	P52565	ARHGDIA	P17252	PRKCA	T132	K138E	138	Missense	distal	6	no	17.698	17.603	EPSD	TCGA;ICGC;COSMIC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	P52565	ARHGDIA	P17252	PRKCA	T132	K135E	135	Missense	distal	3	no	17.698	17.082	EPSD	TCGA;ICGC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	P52565	ARHGDIA	P17252	PRKCA	S176	R180H	180	Missense	distal	4	no	17.490	17.208	EPSD	TCGA;COSMIC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	P52565	ARHGDIA	P17252	PRKCA	S176	I177M	177	Missense	proximal	1	no	17.490	16.440	EPSD	TCGA;COSMIC	16.704	Loss
AGC_PKC_PKCa_PRKCA_ST	P53004	BLVRA	P17252	PRKCA	S21	G20S	20	Missense	proximal	-1	no	24.825	24.577	EPSD	TCGA	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	P53004	BLVRA	P17252	PRKCA	S21	R23W	23	Missense	proximal	2	no	24.825	19.385	EPSD	TCGA;ICGC;COSMIC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	P53004	BLVRA	P17252	PRKCA	T207	K200E	200	Missense	distal	-7	no	18.781	18.773	EPSD	TCGA;ICGC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	P53004	BLVRA	P17252	PRKCA	S230	S235C	235	Missense	distal	5	no	19.508	18.918	PhosphoSitePlus;EPSD	TCGA;ICGC;COSMIC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	P53004	BLVRA	P17252	PRKCA	S230	K234N	234	Missense	distal	4	no	19.508	18.381	PhosphoSitePlus;EPSD	TCGA	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	P53004	BLVRA	P17252	PRKCA	S230	S237C	237	Missense	distal	7	no	19.508	19.331	PhosphoSitePlus;EPSD	TCGA;ICGC;COSMIC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	P53004	BLVRA	P17252	PRKCA	S230	G236W	236	Missense	distal	6	no	19.508	19.410	PhosphoSitePlus;EPSD	TCGA;ICGC;COSMIC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	P53004	BLVRA	P17252	PRKCA	S230	N226H	226	Missense	distal	-4	no	19.508	19.457	PhosphoSitePlus;EPSD	TCGA;ICGC;COSMIC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	P53004	BLVRA	P17252	PRKCA	S230	H232N	232	Missense	proximal	2	no	19.508	19.161	PhosphoSitePlus;EPSD	TCGA;ICGC;COSMIC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	P19429	TNNI3	P17252	PRKCA	S23	I19T	19	Missense	distal	-4	no	20.612	20.392	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	P19429	TNNI3	P17252	PRKCA	S23	Y29H	29	Missense	distal	6	no	20.612	20.587	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	P19429	TNNI3	P17252	PRKCA	S23	R21C	21	Missense	proximal	-2	no	20.612	18.912	EPSD;PhosphoSitePlus	TCGA	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	P19429	TNNI3	P17252	PRKCA	S23	R22H	22	Missense	proximal	-1	no	20.612	20.289	EPSD;PhosphoSitePlus	TCGA;ICGC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	P19429	TNNI3	P17252	PRKCA	S24	I19T	19	Missense	distal	-5	no	23.700	24.172	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	16.704	Up-regulation
AGC_PKC_PKCa_PRKCA_ST	P19429	TNNI3	P17252	PRKCA	S24	Y29H	29	Missense	distal	5	no	23.700	23.555	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	P19429	TNNI3	P17252	PRKCA	S24	R21C	21	Missense	distal	-3	no	23.700	20.960	EPSD;PhosphoSitePlus	TCGA	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	P19429	TNNI3	P17252	PRKCA	S24	R22H	22	Missense	proximal	-2	no	23.700	19.146	EPSD;PhosphoSitePlus	TCGA;ICGC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	P19429	TNNI3	P17252	PRKCA	S39	K40R	40	Missense	proximal	1	no	19.795	19.757	EPSD	TCGA;COSMIC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	P19429	TNNI3	P17252	PRKCA	S42	K40R	40	Missense	proximal	-2	no	19.146	20.774	EPSD;PhosphoSitePlus	TCGA;COSMIC	16.704	Up-regulation
AGC_PKC_PKCa_PRKCA_ST	P19429	TNNI3	P17252	PRKCA	S44	K40R	40	Missense	distal	-4	no	17.602	17.567	EPSD;PhosphoSitePlus	TCGA;COSMIC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	P19429	TNNI3	P17252	PRKCA	S77	S77N	77	Missense	central	0	yes	21.044	0.000	EPSD	TCGA	16.704	Loss
AGC_PKC_PKCa_PRKCA_ST	P19429	TNNI3	P17252	PRKCA	T143	R136Q	136	Missense	distal	-7	no	21.018	21.009	EPSD;PhosphoSitePlus	TCGA;COSMIC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	P19429	TNNI3	P17252	PRKCA	T143	R141W	141	Missense	proximal	-2	no	21.018	19.020	EPSD;PhosphoSitePlus	TCGA	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	P19429	TNNI3	P17252	PRKCA	T143	R145Q	145	Missense	proximal	2	no	21.018	17.184	EPSD;PhosphoSitePlus	TCGA;COSMIC;GDSC;CCLE	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	P08183	ABCB1	P17252	PRKCA	S23	K30N	30	Missense	distal	7	no	19.118	18.998	EPSD	TCGA;ICGC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	P08183	ABCB1	P17252	PRKCA	S23	F16L	16	Missense	distal	-7	no	19.118	19.120	EPSD	TCGA;ICGC	16.704	Up-regulation
AGC_PKC_PKCa_PRKCA_ST	P08183	ABCB1	P17252	PRKCA	S35	P32Q	32	Missense	distal	-3	no	16.230	17.221	EPSD	TCGA;ICGC;COSMIC	16.704	Gain
AGC_PKC_PKCa_PRKCA_ST	P08183	ABCB1	P17252	PRKCA	S590	V597A	597	Missense	distal	7	no	16.664	16.718	EPSD	TCGA;COSMIC	16.704	Gain
AGC_PKC_PKCa_PRKCA_ST	P08183	ABCB1	P17252	PRKCA	T591	V597A	597	Missense	distal	6	no	19.388	19.507	EPSD	TCGA;COSMIC	16.704	Up-regulation
AGC_PKC_PKCa_PRKCA_ST	P08183	ABCB1	P17252	PRKCA	T591	R593C	593	Missense	proximal	2	no	19.388	15.038	EPSD	TCGA;COSMIC	16.704	Loss
AGC_PKC_PKCa_PRKCA_ST	P08183	ABCB1	P17252	PRKCA	T591	V597I	597	Missense	distal	6	no	19.388	19.443	EPSD	TCGA;COSMIC	16.704	Up-regulation
AGC_PKC_PKCa_PRKCA_ST	P08183	ABCB1	P17252	PRKCA	T591	A595G	595	Missense	distal	4	no	19.388	19.015	EPSD	TCGA;COSMIC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	P08183	ABCB1	P17252	PRKCA	S661	S667L	667	Missense	distal	6	no	20.128	20.117	PhosphoSitePlus;EPSD	TCGA;ICGC;COSMIC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	P08183	ABCB1	P17252	PRKCA	S661	S658P	658	Missense	distal	-3	no	20.128	19.150	PhosphoSitePlus;EPSD	TCGA;ICGC;COSMIC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	P08183	ABCB1	P17252	PRKCA	S661	R659I	659	Missense	proximal	-2	no	20.128	16.540	PhosphoSitePlus;EPSD	TCGA;ICGC;COSMIC	16.704	Loss
AGC_PKC_PKCa_PRKCA_ST	P08183	ABCB1	P17252	PRKCA	S661	K665Q	665	Missense	distal	4	no	20.128	19.740	PhosphoSitePlus;EPSD	TCGA;ICGC;COSMIC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	P08183	ABCB1	P17252	PRKCA	S661	R664I	664	Missense	distal	3	no	20.128	17.579	PhosphoSitePlus;EPSD	TCGA;ICGC;COSMIC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	P08183	ABCB1	P17252	PRKCA	S661	L662I	662	Missense	proximal	1	no	20.128	20.965	PhosphoSitePlus;EPSD	TCGA;ICGC;COSMIC	16.704	Up-regulation
AGC_PKC_PKCa_PRKCA_ST	P08183	ABCB1	P17252	PRKCA	S667	S667L	667	Missense	central	0	yes	24.429	0.000	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	16.704	Loss
AGC_PKC_PKCa_PRKCA_ST	P08183	ABCB1	P17252	PRKCA	S667	G674A	674	Missense	distal	7	no	24.429	24.406	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	P08183	ABCB1	P17252	PRKCA	S667	V672I	672	Missense	distal	5	no	24.429	24.517	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	16.704	Up-regulation
AGC_PKC_PKCa_PRKCA_ST	P08183	ABCB1	P17252	PRKCA	S667	K665Q	665	Missense	proximal	-2	no	24.429	24.298	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	P08183	ABCB1	P17252	PRKCA	S667	R664I	664	Missense	distal	-3	no	24.429	19.942	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	P08183	ABCB1	P17252	PRKCA	S667	L662I	662	Missense	distal	-5	no	24.429	23.986	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	P08183	ABCB1	P17252	PRKCA	S671	S667L	667	Missense	distal	-4	no	22.872	22.441	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	P08183	ABCB1	P17252	PRKCA	S671	G674A	674	Missense	distal	3	no	22.872	21.914	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	P08183	ABCB1	P17252	PRKCA	S671	V672I	672	Missense	proximal	1	no	22.872	23.584	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	16.704	Up-regulation
AGC_PKC_PKCa_PRKCA_ST	P08183	ABCB1	P17252	PRKCA	S671	K665Q	665	Missense	distal	-6	no	22.872	22.736	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	P08183	ABCB1	P17252	PRKCA	S671	R664I	664	Missense	distal	-7	no	22.872	22.858	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	P08183	ABCB1	P17252	PRKCA	S675	K681E	681	Missense	distal	6	no	18.840	18.746	EPSD	TCGA;ICGC;COSMIC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	P08183	ABCB1	P17252	PRKCA	S675	G674A	674	Missense	proximal	-1	no	18.840	18.033	EPSD	TCGA;ICGC;COSMIC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	P08183	ABCB1	P17252	PRKCA	S675	L682F	682	Missense	distal	7	no	18.840	18.774	EPSD	TCGA;ICGC;COSMIC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	P08183	ABCB1	P17252	PRKCA	S675	V672I	672	Missense	distal	-3	no	18.840	18.042	EPSD	TCGA;ICGC;COSMIC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	P08183	ABCB1	P17252	PRKCA	S683	K681E	681	Missense	proximal	-2	no	22.617	20.118	EPSD	TCGA;ICGC;COSMIC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	P08183	ABCB1	P17252	PRKCA	S683	L688V	688	Missense	distal	5	no	22.617	22.526	EPSD	TCGA;ICGC;COSMIC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	P08183	ABCB1	P17252	PRKCA	S683	L682F	682	Missense	proximal	-1	no	22.617	22.329	EPSD	TCGA;ICGC;COSMIC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	P08183	ABCB1	P17252	PRKCA	S683	A687D	687	Missense	distal	4	no	22.617	22.248	EPSD	TCGA;ICGC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	O14745	SLC9A3R1	P17252	PRKCA	S170	G176A	176	Missense	distal	6	no	18.463	18.570	EPSD	TCGA	16.704	Up-regulation
AGC_PKC_PKCa_PRKCA_ST	O14745	SLC9A3R1	P17252	PRKCA	S280	P283T	283	Missense	distal	3	no	17.370	17.065	EPSD	TCGA;ICGC;COSMIC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	O14745	SLC9A3R1	P17252	PRKCA	S302	P304R	304	Missense	proximal	2	no	16.160	21.362	EPSD	TCGA	16.704	Gain
AGC_PKC_PKCa_PRKCA_ST	O14745	SLC9A3R1	P17252	PRKCA	S308	P304R	304	Missense	distal	-4	no	17.418	17.783	EPSD	TCGA	16.704	Up-regulation
AGC_PKC_PKCa_PRKCA_ST	O14745	SLC9A3R1	P17252	PRKCA	S339	R342Q	342	Missense	distal	3	no	19.714	17.261	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	O14745	SLC9A3R1	P17252	PRKCA	S339	P344S	344	Missense	distal	5	no	19.714	19.554	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	O14745	SLC9A3R1	P17252	PRKCA	S340	R342Q	342	Missense	proximal	2	no	21.773	17.938	PhosphoSitePlus;EPSD	TCGA;ICGC;COSMIC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	O14745	SLC9A3R1	P17252	PRKCA	S340	P344S	344	Missense	distal	4	no	21.773	21.972	PhosphoSitePlus;EPSD	TCGA;ICGC;COSMIC	16.704	Up-regulation
AGC_PKC_PKCa_PRKCA_ST	Q96RI1	NR1H4	P17252	PRKCA	S31	A35T	35	Missense	distal	4	no	18.330	17.882	EPSD	TCGA;ICGC;COSMIC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	Q96RI1	NR1H4	P17252	PRKCA	S31	M30I	30	Missense	proximal	-1	no	18.330	16.387	EPSD	TCGA;ICGC;COSMIC	16.704	Loss
AGC_PKC_PKCa_PRKCA_ST	Q96RI1	NR1H4	P17252	PRKCA	S31	E28V	28	Missense	distal	-3	no	18.330	19.578	EPSD	TCGA;ICGC;COSMIC	16.704	Up-regulation
AGC_PKC_PKCa_PRKCA_ST	Q96RI1	NR1H4	P17252	PRKCA	S31	V38F	38	Missense	distal	7	no	18.330	18.322	EPSD	TCGA;COSMIC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	Q96RI1	NR1H4	P17252	PRKCA	S31	S31R	31	Missense	central	0	yes	18.330	0.000	EPSD	TCGA;ICGC;COSMIC	16.704	Loss
AGC_PKC_PKCa_PRKCA_ST	Q96RI1	NR1H4	P17252	PRKCA	S31	E28K	28	Missense	distal	-3	no	18.330	21.242	EPSD	TCGA;ICGC;COSMIC	16.704	Up-regulation
AGC_PKC_PKCa_PRKCA_ST	Q96RI1	NR1H4	P17252	PRKCA	S164	R163S	163	Missense	proximal	-1	no	21.279	20.892	EPSD	TCGA;COSMIC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	Q96RI1	NR1H4	P17252	PRKCA	S164	R163T	163	Missense	proximal	-1	no	21.279	20.514	EPSD	TCGA;COSMIC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	Q96RI1	NR1H4	P17252	PRKCA	S164	A169S	169	Missense	distal	5	no	21.279	21.176	EPSD	TCGA;COSMIC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	Q96RI1	NR1H4	P17252	PRKCA	S164	R162M	162	Missense	proximal	-2	no	21.279	19.298	EPSD	TCGA;COSMIC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	Q96RI1	NR1H4	P17252	PRKCA	S164	R162S	162	Missense	proximal	-2	no	21.279	17.977	EPSD	TCGA;COSMIC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	Q96RI1	NR1H4	P17252	PRKCA	S164	G159D	159	Missense	distal	-5	no	21.279	21.184	EPSD	TCGA	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	Q96RI1	NR1H4	P17252	PRKCA	S164	R163I	163	Missense	proximal	-1	no	21.279	19.609	EPSD	TCGA;COSMIC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	Q96RI1	NR1H4	P17252	PRKCA	S164	A169T	169	Missense	distal	5	no	21.279	21.001	EPSD	TCGA	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	Q96RI1	NR1H4	P17252	PRKCA	S467	N471S	471	Missense	distal	4	no	16.093	16.803	EPSD	TCGA;COSMIC	16.704	Gain
AGC_PKC_PKCa_PRKCA_ST	P78536	ADAM17	P17252	PRKCA	S4	L5F	5	Missense	proximal	1	no	17.531	18.189	EPSD	TCGA;ICGC;COSMIC	16.704	Up-regulation
AGC_PKC_PKCa_PRKCA_ST	P78536	ADAM17	P17252	PRKCA	S4	S10R	10	Missense	distal	6	no	17.531	17.603	EPSD	TCGA;ICGC;COSMIC	16.704	Up-regulation
AGC_PKC_PKCa_PRKCA_ST	P78536	ADAM17	P17252	PRKCA	S10	L5F	5	Missense	distal	-5	no	18.408	18.212	EPSD	TCGA;ICGC;COSMIC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	P78536	ADAM17	P17252	PRKCA	S10	S10R	10	Missense	central	0	yes	18.408	0.000	EPSD	TCGA;ICGC;COSMIC	16.704	Loss
AGC_PKC_PKCa_PRKCA_ST	P78536	ADAM17	P17252	PRKCA	S180	P181L	181	Missense	proximal	1	no	19.151	19.578	EPSD	TCGA;ICGC;COSMIC	16.704	Up-regulation
AGC_PKC_PKCa_PRKCA_ST	P78536	ADAM17	P17252	PRKCA	S180	S176L	176	Missense	distal	-4	no	19.151	18.720	EPSD	TCGA;ICGC;COSMIC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	P78536	ADAM17	P17252	PRKCA	S180	R177C	177	Missense	distal	-3	no	19.151	16.411	EPSD	TCGA;ICGC;COSMIC	16.704	Loss
AGC_PKC_PKCa_PRKCA_ST	P78536	ADAM17	P17252	PRKCA	S808	A806V	806	Missense	proximal	-2	no	16.655	16.899	EPSD	TCGA;ICGC;COSMIC	16.704	Gain
AGC_PKC_PKCa_PRKCA_ST	O95243	MBD4	P17252	PRKCA	S122	S123L	123	Missense	proximal	1	no	17.120	17.946	EPSD	TCGA;ICGC;COSMIC	16.704	Up-regulation
AGC_PKC_PKCa_PRKCA_ST	O95243	MBD4	P17252	PRKCA	S122	K117R	117	Missense	distal	-5	no	17.120	17.132	EPSD	TCGA;ICGC;COSMIC	16.704	Up-regulation
AGC_PKC_PKCa_PRKCA_ST	O95243	MBD4	P17252	PRKCA	S122	L124R	124	Missense	proximal	2	no	17.120	22.107	EPSD	TCGA;ICGC;COSMIC	16.704	Up-regulation
AGC_PKC_PKCa_PRKCA_ST	O95243	MBD4	P17252	PRKCA	S122	K117T	117	Missense	distal	-5	no	17.120	17.033	EPSD	TCGA;ICGC;COSMIC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	O95243	MBD4	P17252	PRKCA	S253	G249R	249	Missense	distal	-4	no	16.828	16.930	EPSD	TCGA;ICGC;COSMIC	16.704	Up-regulation
AGC_PKC_PKCa_PRKCA_ST	O95243	MBD4	P17252	PRKCA	S253	R251M	251	Missense	proximal	-2	no	16.828	14.847	EPSD	TCGA;ICGC;COSMIC	16.704	Loss
AGC_PKC_PKCa_PRKCA_ST	O95243	MBD4	P17252	PRKCA	S253	C254Y	254	Missense	proximal	1	no	16.828	19.301	EPSD	TCGA;ICGC;COSMIC	16.704	Up-regulation
AGC_PKC_PKCa_PRKCA_ST	O95243	MBD4	P17252	PRKCA	S253	S253R	253	Missense	central	0	yes	16.828	0.000	EPSD	TCGA;ICGC	16.704	Loss
AGC_PKC_PKCa_PRKCA_ST	O95243	MBD4	P17252	PRKCA	S415	Y422H	422	Missense	distal	7	no	17.854	17.835	EPSD	TCGA;COSMIC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	P48048	KCNJ1	P17252	PRKCA	S4	N2S	2	Missense	proximal	-2	no	17.686	17.580	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	P48048	KCNJ1	P17252	PRKCA	S5	N2S	2	Missense	distal	-3	no	15.731	17.088	EPSD	TCGA;ICGC;COSMIC	16.704	Gain
AGC_PKC_PKCa_PRKCA_ST	P48048	KCNJ1	P17252	PRKCA	S44	R48W	48	Missense	distal	4	no	18.873	17.337	EPSD	TCGA;COSMIC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	P48048	KCNJ1	P17252	PRKCA	S44	C49Y	49	Missense	distal	5	no	18.873	19.490	EPSD	TCGA;COSMIC	16.704	Up-regulation
AGC_PKC_PKCa_PRKCA_ST	P48048	KCNJ1	P17252	PRKCA	S44	R39K	39	Missense	distal	-5	no	18.873	18.860	EPSD	TCGA;COSMIC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	P48048	KCNJ1	P17252	PRKCA	S44	R37Q	37	Missense	distal	-7	no	18.873	18.865	EPSD	TCGA;COSMIC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	P48048	KCNJ1	P17252	PRKCA	T191	A189D	189	Missense	proximal	-2	no	18.331	17.998	EPSD	TCGA;COSMIC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	P48048	KCNJ1	P17252	PRKCA	T191	R188C	188	Missense	distal	-3	no	18.331	15.592	EPSD	TCGA;COSMIC	16.704	Loss
AGC_PKC_PKCa_PRKCA_ST	P48048	KCNJ1	P17252	PRKCA	S201	C208Y	208	Missense	distal	7	no	18.433	18.604	PhosphoSitePlus;EPSD	TCGA;COSMIC	16.704	Up-regulation
AGC_PKC_PKCa_PRKCA_ST	P55042	RRAD	P17252	PRKCA	S257	R252L	252	Missense	distal	-5	no	19.878	19.750	PhosphoSitePlus;EPSD	TCGA;ICGC;COSMIC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	P55042	RRAD	P17252	PRKCA	S257	R254H	254	Missense	distal	-3	no	19.878	16.021	PhosphoSitePlus;EPSD	TCGA;ICGC;COSMIC	16.704	Loss
AGC_PKC_PKCa_PRKCA_ST	P55042	RRAD	P17252	PRKCA	S257	E259K	259	Missense	proximal	2	no	19.878	25.157	PhosphoSitePlus;EPSD	TCGA;ICGC;COSMIC	16.704	Up-regulation
AGC_PKC_PKCa_PRKCA_ST	P55042	RRAD	P17252	PRKCA	S257	R263Q	263	Missense	distal	6	no	19.878	19.755	PhosphoSitePlus;EPSD	TCGA;ICGC;COSMIC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	P55042	RRAD	P17252	PRKCA	S257	R264Q	264	Missense	distal	7	no	19.878	19.873	PhosphoSitePlus;EPSD	TCGA;ICGC;COSMIC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	P55042	RRAD	P17252	PRKCA	S273	R271Q	271	Missense	proximal	-2	no	20.547	18.788	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	P55042	RRAD	P17252	PRKCA	S273	R280H	280	Missense	distal	7	no	20.547	20.475	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	P55042	RRAD	P17252	PRKCA	S273	E272D	272	Missense	proximal	-1	no	20.547	20.033	EPSD;PhosphoSitePlus	TCGA;ICGC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	P55042	RRAD	P17252	PRKCA	S273	R269Q	269	Missense	distal	-4	no	20.547	20.170	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	P55042	RRAD	P17252	PRKCA	S273	K279R	279	Missense	distal	6	no	20.547	20.559	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	16.704	Up-regulation
AGC_PKC_PKCa_PRKCA_ST	P55042	RRAD	P17252	PRKCA	S273	K277R	277	Missense	distal	4	no	20.547	20.376	EPSD;PhosphoSitePlus	TCGA	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	P55042	RRAD	P17252	PRKCA	S290	R284H	284	Missense	distal	-6	no	18.882	18.814	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	P55042	RRAD	P17252	PRKCA	S290	R296C	296	Missense	distal	6	no	18.882	18.643	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	P55042	RRAD	P17252	PRKCA	S290	V286I	286	Missense	distal	-4	no	18.882	18.912	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	16.704	Up-regulation
AGC_PKC_PKCa_PRKCA_ST	P11831	SRF	P17252	PRKCA	S237	E242K	242	Missense	distal	5	no	18.458	18.872	EPSD	TCGA;COSMIC	16.704	Up-regulation
AGC_PKC_PKCa_PRKCA_ST	P11831	SRF	P17252	PRKCA	S237	T244R	244	Missense	distal	7	no	18.458	18.498	EPSD	TCGA;COSMIC	16.704	Up-regulation
AGC_PKC_PKCa_PRKCA_ST	P04004	VTN	P17252	PRKCA	S171	D166N	166	Missense	distal	-5	no	16.706	16.735	EPSD	TCGA;ICGC;COSMIC	16.704	Up-regulation
AGC_PKC_PKCa_PRKCA_ST	P04004	VTN	P17252	PRKCA	S171	G170R	170	Missense	proximal	-1	no	16.706	16.845	EPSD	TCGA;ICGC;COSMIC	16.704	Up-regulation
AGC_PKC_PKCa_PRKCA_ST	P04004	VTN	P17252	PRKCA	S171	K168N	168	Missense	distal	-3	no	16.706	14.506	EPSD	TCGA;ICGC	16.704	Loss
AGC_PKC_PKCa_PRKCA_ST	P04004	VTN	P17252	PRKCA	S171	L172R	172	Missense	proximal	1	no	16.706	17.054	EPSD	TCGA;ICGC;COSMIC	16.704	Up-regulation
AGC_PKC_PKCa_PRKCA_ST	P04004	VTN	P17252	PRKCA	S171	R176Q	176	Missense	distal	5	no	16.706	16.698	EPSD	TCGA;ICGC;COSMIC	16.704	Loss
AGC_PKC_PKCa_PRKCA_ST	P04004	VTN	P17252	PRKCA	S225	L221H	221	Missense	distal	-4	no	17.604	17.654	EPSD	TCGA;ICGC;COSMIC	16.704	Up-regulation
AGC_PKC_PKCa_PRKCA_ST	P04004	VTN	P17252	PRKCA	S225	R229H	229	Missense	distal	4	no	17.604	17.322	EPSD	TCGA;ICGC;COSMIC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	P04004	VTN	P17252	PRKCA	S225	R229C	229	Missense	distal	4	no	17.604	16.203	EPSD	TCGA;ICGC;COSMIC	16.704	Loss
AGC_PKC_PKCa_PRKCA_ST	P23528	CFL1	P17252	PRKCA	S23	M18L	18	Missense	distal	-5	no	19.343	19.382	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	16.704	Up-regulation
AGC_PKC_PKCa_PRKCA_ST	P23528	CFL1	P17252	PRKCA	S24	M18L	18	Missense	distal	-6	no	21.248	21.186	PhosphoSitePlus;EPSD	TCGA;ICGC;COSMIC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	P23528	CFL1	P17252	PRKCA	S94	K92E	92	Missense	proximal	-2	no	16.730	14.231	EPSD	TCGA;COSMIC	16.704	Loss
AGC_PKC_PKCa_PRKCA_ST	P23528	CFL1	P17252	PRKCA	S119	S120F	120	Missense	proximal	1	no	16.096	17.580	EPSD	TCGA;COSMIC	16.704	Gain
AGC_PKC_PKCa_PRKCA_ST	Q96KS0	EGLN2	P17252	PRKCA	S234	R236C	236	Missense	proximal	2	no	20.437	16.086	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	16.704	Loss
AGC_PKC_PKCa_PRKCA_ST	Q96KS0	EGLN2	P17252	PRKCA	S252	I253S	253	Missense	proximal	1	no	17.169	15.506	EPSD	TCGA;ICGC;COSMIC	16.704	Loss
AGC_PKC_PKCa_PRKCA_ST	Q07869	PPARA	P17252	PRKCA	S163	G165R	165	Missense	proximal	2	no	16.128	21.373	EPSD	TCGA;ICGC;COSMIC	16.704	Gain
AGC_PKC_PKCa_PRKCA_ST	Q07869	PPARA	P17252	PRKCA	S179	R172C	172	Missense	distal	-7	no	19.047	19.028	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	Q07869	PPARA	P17252	PRKCA	S179	R178I	178	Missense	proximal	-1	no	19.047	17.377	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	P15311	EZR	P17252	PRKCA	T325	R320W	320	Missense	distal	-5	no	17.914	17.600	EPSD	TCGA;ICGC;COSMIC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	P15311	EZR	P17252	PRKCA	T325	R330T	330	Missense	distal	5	no	17.914	17.597	EPSD	TCGA;ICGC;COSMIC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	P15311	EZR	P17252	PRKCA	T332	R330T	330	Missense	proximal	-2	no	18.765	15.872	EPSD	TCGA;ICGC;COSMIC	16.704	Loss
AGC_PKC_PKCa_PRKCA_ST	P04637	TP53	P17252	PRKCA	S99	G105C	105	Missense	distal	6	no	17.589	17.500	EPSD	TCGA;ICGC;COSMIC;GDSC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	P04637	TP53	P17252	PRKCA	S99	S106R	106	Missense	distal	7	no	17.589	17.636	EPSD	TCGA;ICGC;COSMIC;GDSC;CCLE	16.704	Up-regulation
AGC_PKC_PKCa_PRKCA_ST	P04637	TP53	P17252	PRKCA	S99	G105R	105	Missense	distal	6	no	17.589	17.739	EPSD	TCGA;ICGC;COSMIC;CCLE	16.704	Up-regulation
AGC_PKC_PKCa_PRKCA_ST	P04637	TP53	P17252	PRKCA	S99	G105V	105	Missense	distal	6	no	17.589	17.578	EPSD	TCGA;ICGC;COSMIC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	P04637	TP53	P17252	PRKCA	S99	G105D	105	Missense	distal	6	no	17.589	17.649	EPSD	TCGA;ICGC;COSMIC	16.704	Up-regulation
AGC_PKC_PKCa_PRKCA_ST	P04637	TP53	P17252	PRKCA	S99	G105S	105	Missense	distal	6	no	17.589	17.667	EPSD	TCGA;ICGC;COSMIC	16.704	Up-regulation
AGC_PKC_PKCa_PRKCA_ST	P04637	TP53	P17252	PRKCA	S99	V97D	97	Missense	proximal	-2	no	17.589	17.013	EPSD	TCGA;ICGC;COSMIC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	P04637	TP53	P17252	PRKCA	S99	P92S	92	Missense	distal	-7	no	17.589	17.592	EPSD	TCGA;ICGC	16.704	Up-regulation
AGC_PKC_PKCa_PRKCA_ST	P04637	TP53	P17252	PRKCA	S149	P151R	151	Missense	proximal	2	no	13.513	18.715	EPSD	TCGA;ICGC;COSMIC	16.704	Gain
AGC_PKC_PKCa_PRKCA_ST	P04637	TP53	P17252	PRKCA	T211	R213Q	213	Missense	proximal	2	no	18.834	15.000	EPSD	TCGA;ICGC;COSMIC;GDSC;CCLE	16.704	Loss
AGC_PKC_PKCa_PRKCA_ST	P04637	TP53	P17252	PRKCA	T211	E204Q	204	Missense	distal	-7	no	18.834	18.838	EPSD	TCGA;ICGC;COSMIC	16.704	Up-regulation
AGC_PKC_PKCa_PRKCA_ST	P04637	TP53	P17252	PRKCA	T211	D208N	208	Missense	distal	-3	no	18.834	19.649	EPSD	TCGA;ICGC;COSMIC	16.704	Up-regulation
AGC_PKC_PKCa_PRKCA_ST	P04637	TP53	P17252	PRKCA	T211	H214R	214	Missense	distal	3	no	18.834	19.546	EPSD	TCGA;ICGC;COSMIC;GDSC;CCLE	16.704	Up-regulation
AGC_PKC_PKCa_PRKCA_ST	P04637	TP53	P17252	PRKCA	T211	V218E	218	Missense	distal	7	no	18.834	18.841	EPSD	TCGA;ICGC;COSMIC	16.704	Up-regulation
AGC_PKC_PKCa_PRKCA_ST	P04637	TP53	P17252	PRKCA	T211	S215I	215	Missense	distal	4	no	18.834	17.389	EPSD	TCGA;ICGC;COSMIC;GDSC;CCLE	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	P04637	TP53	P17252	PRKCA	T211	V216M	216	Missense	distal	5	no	18.834	19.242	EPSD	TCGA;ICGC;COSMIC;GDSC;CCLE	16.704	Up-regulation
AGC_PKC_PKCa_PRKCA_ST	P04637	TP53	P17252	PRKCA	T211	Y205C	205	Missense	distal	-6	no	18.834	18.591	EPSD	TCGA;ICGC;COSMIC;GDSC;CCLE	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	P04637	TP53	P17252	PRKCA	T211	Y205N	205	Missense	distal	-6	no	18.834	18.830	EPSD	TCGA;ICGC;COSMIC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	P04637	TP53	P17252	PRKCA	T211	S215N	215	Missense	distal	4	no	18.834	18.124	EPSD	TCGA;ICGC;COSMIC;GDSC;CCLE	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	P04637	TP53	P17252	PRKCA	T211	T211I	211	Missense	central	0	yes	18.834	0.000	EPSD	TCGA;ICGC;COSMIC;CCLE	16.704	Loss
AGC_PKC_PKCa_PRKCA_ST	P04637	TP53	P17252	PRKCA	T211	V216G	216	Missense	distal	5	no	18.834	18.975	EPSD	TCGA;ICGC;COSMIC	16.704	Up-regulation
AGC_PKC_PKCa_PRKCA_ST	P04637	TP53	P17252	PRKCA	T211	R213L	213	Missense	proximal	2	no	18.834	13.847	EPSD	TCGA;ICGC;COSMIC;GDSC;CCLE	16.704	Loss
AGC_PKC_PKCa_PRKCA_ST	P04637	TP53	P17252	PRKCA	T211	V216E	216	Missense	distal	5	no	18.834	18.986	EPSD	TCGA;ICGC;COSMIC	16.704	Up-regulation
AGC_PKC_PKCa_PRKCA_ST	P04637	TP53	P17252	PRKCA	T211	R209K	209	Missense	proximal	-2	no	18.834	17.206	EPSD	TCGA;COSMIC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	P04637	TP53	P17252	PRKCA	T211	V218G	218	Missense	distal	7	no	18.834	18.912	EPSD	TCGA;ICGC;COSMIC	16.704	Up-regulation
AGC_PKC_PKCa_PRKCA_ST	P04637	TP53	P17252	PRKCA	T211	R213P	213	Missense	proximal	2	no	18.834	13.631	EPSD	TCGA;ICGC;COSMIC	16.704	Loss
AGC_PKC_PKCa_PRKCA_ST	P04637	TP53	P17252	PRKCA	T211	H214L	214	Missense	distal	3	no	18.834	17.308	EPSD	TCGA;ICGC;COSMIC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	P04637	TP53	P17252	PRKCA	T211	Y205H	205	Missense	distal	-6	no	18.834	18.893	EPSD	TCGA;ICGC;COSMIC;CCLE	16.704	Up-regulation
AGC_PKC_PKCa_PRKCA_ST	P04637	TP53	P17252	PRKCA	T211	V216L	216	Missense	distal	5	no	18.834	18.924	EPSD	TCGA;ICGC;COSMIC;GDSC;CCLE	16.704	Up-regulation
AGC_PKC_PKCa_PRKCA_ST	P04637	TP53	P17252	PRKCA	T211	D208G	208	Missense	distal	-3	no	18.834	20.614	EPSD	TCGA;ICGC;COSMIC	16.704	Up-regulation
AGC_PKC_PKCa_PRKCA_ST	P04637	TP53	P17252	PRKCA	T211	Y205S	205	Missense	distal	-6	no	18.834	18.887	EPSD	TCGA;ICGC;COSMIC	16.704	Up-regulation
AGC_PKC_PKCa_PRKCA_ST	P04637	TP53	P17252	PRKCA	T211	S215G	215	Missense	distal	4	no	18.834	18.476	EPSD	TCGA;ICGC;COSMIC;GDSC;CCLE	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	P04637	TP53	P17252	PRKCA	T211	R209S	209	Missense	proximal	-2	no	18.834	15.532	EPSD	TCGA;ICGC;COSMIC	16.704	Loss
AGC_PKC_PKCa_PRKCA_ST	P04637	TP53	P17252	PRKCA	T211	R213G	213	Missense	proximal	2	no	18.834	13.588	EPSD	TCGA;ICGC;COSMIC	16.704	Loss
AGC_PKC_PKCa_PRKCA_ST	P04637	TP53	P17252	PRKCA	T211	Y205F	205	Missense	distal	-6	no	18.834	18.802	EPSD	TCGA;ICGC;COSMIC;GDSC;CCLE	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	P04637	TP53	P17252	PRKCA	T211	Y205D	205	Missense	distal	-6	no	18.834	18.803	EPSD	TCGA;ICGC;COSMIC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	P04637	TP53	P17252	PRKCA	T211	S215R	215	Missense	distal	4	no	18.834	19.080	EPSD	TCGA;ICGC;COSMIC;GDSC;CCLE	16.704	Up-regulation
AGC_PKC_PKCa_PRKCA_ST	P04637	TP53	P17252	PRKCA	T211	R209I	209	Missense	proximal	-2	no	18.834	15.246	EPSD	TCGA;ICGC;COSMIC	16.704	Loss
AGC_PKC_PKCa_PRKCA_ST	P04637	TP53	P17252	PRKCA	T211	T211A	211	Missense	central	0	yes	18.834	0.000	EPSD	TCGA;ICGC;COSMIC;CCLE	16.704	Loss
AGC_PKC_PKCa_PRKCA_ST	P04637	TP53	P17252	PRKCA	T211	E204D	204	Missense	distal	-7	no	18.834	18.837	EPSD	TCGA;ICGC;COSMIC	16.704	Up-regulation
AGC_PKC_PKCa_PRKCA_ST	P04637	TP53	P17252	PRKCA	S215	H214R	214	Missense	proximal	-1	no	16.529	16.852	EPSD	TCGA;ICGC;COSMIC;GDSC;CCLE	16.704	Gain
AGC_PKC_PKCa_PRKCA_ST	P04637	TP53	P17252	PRKCA	S215	V218E	218	Missense	distal	3	no	16.529	17.145	EPSD	TCGA;ICGC;COSMIC	16.704	Gain
AGC_PKC_PKCa_PRKCA_ST	P04637	TP53	P17252	PRKCA	S215	T211I	211	Missense	distal	-4	no	16.529	16.749	EPSD	TCGA;ICGC;COSMIC;CCLE	16.704	Gain
AGC_PKC_PKCa_PRKCA_ST	P04637	TP53	P17252	PRKCA	S215	V218G	218	Missense	distal	3	no	16.529	17.744	EPSD	TCGA;ICGC;COSMIC	16.704	Gain
AGC_PKC_PKCa_PRKCA_ST	P04637	TP53	P17252	PRKCA	S215	T211A	211	Missense	distal	-4	no	16.529	17.278	EPSD	TCGA;ICGC;COSMIC;CCLE	16.704	Gain
AGC_PKC_PKCa_PRKCA_ST	P04637	TP53	P17252	PRKCA	S269	R273C	273	Missense	distal	4	no	17.682	16.280	EPSD	TCGA;ICGC;COSMIC;GDSC;CCLE	16.704	Loss
AGC_PKC_PKCa_PRKCA_ST	P04637	TP53	P17252	PRKCA	S269	C275S	275	Missense	distal	6	no	17.682	17.850	EPSD	TCGA;ICGC;COSMIC	16.704	Up-regulation
AGC_PKC_PKCa_PRKCA_ST	P04637	TP53	P17252	PRKCA	S269	R273L	273	Missense	distal	4	no	17.682	16.643	EPSD	TCGA;ICGC;COSMIC;GDSC;CCLE	16.704	Loss
AGC_PKC_PKCa_PRKCA_ST	P04637	TP53	P17252	PRKCA	S269	E271K	271	Missense	proximal	2	no	17.682	22.961	EPSD	TCGA;ICGC;COSMIC;GDSC;CCLE	16.704	Up-regulation
AGC_PKC_PKCa_PRKCA_ST	P04637	TP53	P17252	PRKCA	S269	C275Y	275	Missense	distal	6	no	17.682	17.868	EPSD	TCGA;ICGC;COSMIC;GDSC;CCLE	16.704	Up-regulation
AGC_PKC_PKCa_PRKCA_ST	P04637	TP53	P17252	PRKCA	S269	R273S	273	Missense	distal	4	no	17.682	17.436	EPSD	TCGA;ICGC;COSMIC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	P04637	TP53	P17252	PRKCA	S269	E271Q	271	Missense	proximal	2	no	17.682	19.548	EPSD	TCGA;ICGC;COSMIC	16.704	Up-regulation
AGC_PKC_PKCa_PRKCA_ST	P04637	TP53	P17252	PRKCA	S269	L265P	265	Missense	distal	-4	no	17.682	17.941	EPSD	TCGA;ICGC;COSMIC;GDSC;CCLE	16.704	Up-regulation
AGC_PKC_PKCa_PRKCA_ST	P04637	TP53	P17252	PRKCA	S269	V272M	272	Missense	distal	3	no	17.682	18.268	EPSD	TCGA;ICGC;COSMIC;GDSC;CCLE	16.704	Up-regulation
AGC_PKC_PKCa_PRKCA_ST	P04637	TP53	P17252	PRKCA	S269	G266E	266	Missense	distal	-3	no	17.682	16.005	EPSD	TCGA;ICGC;COSMIC;GDSC;CCLE	16.704	Loss
AGC_PKC_PKCa_PRKCA_ST	P04637	TP53	P17252	PRKCA	S269	R273P	273	Missense	distal	4	no	17.682	17.236	EPSD	TCGA;ICGC;COSMIC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	P04637	TP53	P17252	PRKCA	S269	F270I	270	Missense	proximal	1	no	17.682	17.860	EPSD	TCGA;ICGC;COSMIC	16.704	Up-regulation
AGC_PKC_PKCa_PRKCA_ST	P04637	TP53	P17252	PRKCA	S269	R273H	273	Missense	distal	4	no	17.682	17.399	EPSD	TCGA;ICGC;COSMIC;GDSC;CCLE	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	P04637	TP53	P17252	PRKCA	S269	A276P	276	Missense	distal	7	no	17.682	17.720	EPSD	TCGA;ICGC;COSMIC	16.704	Up-regulation
AGC_PKC_PKCa_PRKCA_ST	P04637	TP53	P17252	PRKCA	S269	V272L	272	Missense	distal	3	no	17.682	17.298	EPSD	TCGA;ICGC;COSMIC;GDSC;CCLE	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	P04637	TP53	P17252	PRKCA	S269	V274D	274	Missense	distal	5	no	17.682	17.742	EPSD	TCGA;ICGC;COSMIC;CCLE	16.704	Up-regulation
AGC_PKC_PKCa_PRKCA_ST	P04637	TP53	P17252	PRKCA	S269	G266V	266	Missense	distal	-3	no	17.682	17.254	EPSD	TCGA;ICGC;COSMIC;GDSC;CCLE	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	P04637	TP53	P17252	PRKCA	S269	R267L	267	Missense	proximal	-2	no	17.682	14.994	EPSD	TCGA;ICGC;COSMIC;GDSC;CCLE	16.704	Loss
AGC_PKC_PKCa_PRKCA_ST	P04637	TP53	P17252	PRKCA	S269	R267W	267	Missense	proximal	-2	no	17.682	15.684	EPSD	TCGA;ICGC;COSMIC;GDSC;CCLE	16.704	Loss
AGC_PKC_PKCa_PRKCA_ST	P04637	TP53	P17252	PRKCA	S269	R267Q	267	Missense	proximal	-2	no	17.682	15.923	EPSD	TCGA;ICGC;COSMIC;CCLE	16.704	Loss
AGC_PKC_PKCa_PRKCA_ST	P04637	TP53	P17252	PRKCA	S269	C275F	275	Missense	distal	6	no	17.682	17.808	EPSD	TCGA;ICGC;COSMIC;GDSC;CCLE	16.704	Up-regulation
AGC_PKC_PKCa_PRKCA_ST	P04637	TP53	P17252	PRKCA	S269	V274G	274	Missense	distal	5	no	17.682	17.823	EPSD	TCGA;ICGC;COSMIC;CCLE	16.704	Up-regulation
AGC_PKC_PKCa_PRKCA_ST	P04637	TP53	P17252	PRKCA	S269	V274L	274	Missense	distal	5	no	17.682	17.772	EPSD	TCGA;ICGC;COSMIC	16.704	Up-regulation
AGC_PKC_PKCa_PRKCA_ST	P04637	TP53	P17252	PRKCA	S269	G266R	266	Missense	distal	-3	no	17.682	20.943	EPSD	TCGA;ICGC;COSMIC;GDSC;CCLE	16.704	Up-regulation
AGC_PKC_PKCa_PRKCA_ST	P04637	TP53	P17252	PRKCA	S269	R267P	267	Missense	proximal	-2	no	17.682	14.640	EPSD	TCGA;ICGC;COSMIC;GDSC;CCLE	16.704	Loss
AGC_PKC_PKCa_PRKCA_ST	P04637	TP53	P17252	PRKCA	S269	A276D	276	Missense	distal	7	no	17.682	17.686	EPSD	TCGA;ICGC;COSMIC	16.704	Up-regulation
AGC_PKC_PKCa_PRKCA_ST	P04637	TP53	P17252	PRKCA	S269	L265R	265	Missense	distal	-4	no	17.682	18.306	EPSD	TCGA;ICGC;COSMIC	16.704	Up-regulation
AGC_PKC_PKCa_PRKCA_ST	P04637	TP53	P17252	PRKCA	S269	R267G	267	Missense	proximal	-2	no	17.682	14.810	EPSD	TCGA;ICGC;COSMIC	16.704	Loss
AGC_PKC_PKCa_PRKCA_ST	P04637	TP53	P17252	PRKCA	S269	F270C	270	Missense	proximal	1	no	17.682	14.536	EPSD	TCGA;ICGC;COSMIC	16.704	Loss
AGC_PKC_PKCa_PRKCA_ST	P04637	TP53	P17252	PRKCA	S269	E271V	271	Missense	proximal	2	no	17.682	18.368	EPSD	TCGA;ICGC;COSMIC	16.704	Up-regulation
AGC_PKC_PKCa_PRKCA_ST	P04637	TP53	P17252	PRKCA	S269	G262V	262	Missense	distal	-7	no	17.682	17.678	EPSD	TCGA;ICGC;COSMIC;GDSC;CCLE	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	P04637	TP53	P17252	PRKCA	S269	V274F	274	Missense	distal	5	no	17.682	17.997	EPSD	TCGA;ICGC;COSMIC;GDSC;CCLE	16.704	Up-regulation
AGC_PKC_PKCa_PRKCA_ST	P04637	TP53	P17252	PRKCA	S269	F270S	270	Missense	proximal	1	no	17.682	16.198	EPSD	TCGA;ICGC;COSMIC	16.704	Loss
AGC_PKC_PKCa_PRKCA_ST	P04637	TP53	P17252	PRKCA	S269	C275R	275	Missense	distal	6	no	17.682	17.921	EPSD	TCGA;ICGC;COSMIC	16.704	Up-regulation
AGC_PKC_PKCa_PRKCA_ST	P04637	TP53	P17252	PRKCA	S269	C275G	275	Missense	distal	6	no	17.682	17.772	EPSD	TCGA;ICGC;COSMIC;GDSC;CCLE	16.704	Up-regulation
AGC_PKC_PKCa_PRKCA_ST	P04637	TP53	P17252	PRKCA	S269	A276G	276	Missense	distal	7	no	17.682	17.705	EPSD	TCGA;ICGC;COSMIC	16.704	Up-regulation
AGC_PKC_PKCa_PRKCA_ST	P04637	TP53	P17252	PRKCA	S269	V272G	272	Missense	distal	3	no	17.682	18.896	EPSD	TCGA;ICGC;COSMIC	16.704	Up-regulation
AGC_PKC_PKCa_PRKCA_ST	P04637	TP53	P17252	PRKCA	S269	R273G	273	Missense	distal	4	no	17.682	17.078	EPSD	TCGA;ICGC;COSMIC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	P04637	TP53	P17252	PRKCA	S269	F270V	270	Missense	proximal	1	no	17.682	17.149	EPSD	TCGA;ICGC;COSMIC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	P04637	TP53	P17252	PRKCA	S269	C275W	275	Missense	distal	6	no	17.682	17.673	EPSD	TCGA;ICGC;COSMIC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	P04637	TP53	P17252	PRKCA	S269	V272A	272	Missense	distal	3	no	17.682	17.938	EPSD	TCGA;ICGC;COSMIC	16.704	Up-regulation
AGC_PKC_PKCa_PRKCA_ST	P04637	TP53	P17252	PRKCA	S269	F270L	270	Missense	proximal	1	no	17.682	17.024	EPSD	TCGA;ICGC;COSMIC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	P04637	TP53	P17252	PRKCA	T284	E286K	286	Missense	proximal	2	no	12.156	17.435	EPSD	TCGA;ICGC;COSMIC;GDSC;CCLE	16.704	Gain
AGC_PKC_PKCa_PRKCA_ST	P04637	TP53	P17252	PRKCA	T304	A307V	307	Missense	distal	3	no	16.706	16.450	EPSD	TCGA;ICGC;COSMIC;GDSC	16.704	Loss
AGC_PKC_PKCa_PRKCA_ST	P04637	TP53	P17252	PRKCA	S371	S376C	376	Missense	distal	5	no	18.173	17.583	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	P04637	TP53	P17252	PRKCA	S371	Q375K	375	Missense	distal	4	no	18.173	18.561	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	16.704	Up-regulation
AGC_PKC_PKCa_PRKCA_ST	P04637	TP53	P17252	PRKCA	T377	S376C	376	Missense	proximal	-1	no	17.083	14.810	PhosphoSitePlus;EPSD	TCGA;ICGC;COSMIC	16.704	Loss
AGC_PKC_PKCa_PRKCA_ST	P04637	TP53	P17252	PRKCA	T377	Q375K	375	Missense	proximal	-2	no	17.083	17.214	PhosphoSitePlus;EPSD	TCGA;ICGC;COSMIC	16.704	Up-regulation
AGC_PKC_PKCa_PRKCA_ST	P38936	CDKN1A	P17252	PRKCA	S146	D149H	149	Missense	distal	3	no	15.782	16.795	PhosphoSitePlus;EPSD	TCGA;ICGC;COSMIC	16.704	Gain
AGC_PKC_PKCa_PRKCA_ST	P38936	CDKN1A	P17252	PRKCA	S153	S153C	153	Missense	central	0	yes	18.429	0.000	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	16.704	Loss
AGC_PKC_PKCa_PRKCA_ST	P38936	CDKN1A	P17252	PRKCA	S153	R155H	155	Missense	proximal	2	no	18.429	13.405	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC;CCLE	16.704	Loss
AGC_PKC_PKCa_PRKCA_ST	P38936	CDKN1A	P17252	PRKCA	S153	D149H	149	Missense	distal	-4	no	18.429	18.726	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	16.704	Up-regulation
AGC_PKC_PKCa_PRKCA_ST	P60983	GMFB	P17252	PRKCA	T27	A30T	30	Missense	distal	3	no	16.999	16.761	EPSD	TCGA;ICGC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	P60880	SNAP25	P17252	PRKCA	S28	A22G	22	Missense	distal	-6	no	21.165	21.168	EPSD	TCGA;ICGC;COSMIC	16.704	Up-regulation
AGC_PKC_PKCa_PRKCA_ST	P60880	SNAP25	P17252	PRKCA	S28	S25L	25	Missense	distal	-3	no	21.165	19.680	EPSD	TCGA;ICGC;COSMIC;GDSC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	P60880	SNAP25	P17252	PRKCA	S28	S28I	28	Missense	central	0	yes	21.165	0.000	EPSD	TCGA;ICGC	16.704	Loss
AGC_PKC_PKCa_PRKCA_ST	P60880	SNAP25	P17252	PRKCA	T138	E143K	143	Missense	distal	5	no	16.985	17.399	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	16.704	Up-regulation
AGC_PKC_PKCa_PRKCA_ST	P60880	SNAP25	P17252	PRKCA	S187	E183K	183	Missense	distal	-4	no	16.558	17.289	PhosphoSitePlus;EPSD	TCGA;ICGC;COSMIC	16.704	Gain
AGC_PKC_PKCa_PRKCA_ST	Q8NF50	DOCK8	P17252	PRKCA	S446	A449V	449	Missense	distal	3	no	22.582	22.326	EPSD	TCGA;COSMIC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	Q8NF50	DOCK8	P17252	PRKCA	S446	L450I	450	Missense	distal	4	no	22.582	21.930	EPSD	TCGA;COSMIC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	Q8NF50	DOCK8	P17252	PRKCA	S446	A440T	440	Missense	distal	-6	no	22.582	22.493	EPSD	TCGA;COSMIC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	Q8NF50	DOCK8	P17252	PRKCA	S495	S494L	494	Missense	proximal	-1	no	17.500	17.081	EPSD	TCGA;COSMIC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	Q8NF50	DOCK8	P17252	PRKCA	S902	D907Y	907	Missense	distal	5	no	17.839	18.086	EPSD	TCGA;COSMIC	16.704	Up-regulation
AGC_PKC_PKCa_PRKCA_ST	Q8NF50	DOCK8	P17252	PRKCA	S902	A909T	909	Missense	distal	7	no	17.839	17.847	EPSD	TCGA;COSMIC	16.704	Up-regulation
AGC_PKC_PKCa_PRKCA_ST	Q8NF50	DOCK8	P17252	PRKCA	S902	D907N	907	Missense	distal	5	no	17.839	17.838	EPSD	TCGA;COSMIC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	Q8NF50	DOCK8	P17252	PRKCA	S902	R899Q	899	Missense	distal	-3	no	17.839	14.981	EPSD	TCGA;COSMIC	16.704	Loss
AGC_PKC_PKCa_PRKCA_ST	Q8NF50	DOCK8	P17252	PRKCA	S902	A909V	909	Missense	distal	7	no	17.839	17.784	EPSD	TCGA;COSMIC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	Q8NF50	DOCK8	P17252	PRKCA	S956	A955V	955	Missense	proximal	-1	no	21.610	20.707	EPSD	TCGA;ICGC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	Q8NF50	DOCK8	P17252	PRKCA	S956	F960S	960	Missense	distal	4	no	21.610	21.972	EPSD	TCGA	16.704	Up-regulation
AGC_PKC_PKCa_PRKCA_ST	Q8NF50	DOCK8	P17252	PRKCA	S1091	M1092I	1092	Missense	proximal	1	no	16.425	17.475	EPSD	TCGA;COSMIC	16.704	Gain
AGC_PKC_PKCa_PRKCA_ST	Q8NF50	DOCK8	P17252	PRKCA	S2077	P2071T	2071	Missense	distal	-6	no	21.009	20.915	EPSD;PhosphoSitePlus	TCGA;COSMIC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	Q8NF50	DOCK8	P17252	PRKCA	S2077	S2082F	2082	Missense	distal	5	no	21.009	21.043	EPSD;PhosphoSitePlus	TCGA;COSMIC	16.704	Up-regulation
AGC_PKC_PKCa_PRKCA_ST	Q8NF50	DOCK8	P17252	PRKCA	S2077	K2070N	2070	Missense	distal	-7	no	21.009	21.004	EPSD;PhosphoSitePlus	TCGA;COSMIC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	Q8NF50	DOCK8	P17252	PRKCA	S2082	S2082F	2082	Missense	central	0	yes	16.915	0.000	EPSD;PhosphoSitePlus	TCGA;COSMIC	16.704	Loss
AGC_PKC_PKCa_PRKCA_ST	Q8NF50	DOCK8	P17252	PRKCA	S2087	S2082F	2082	Missense	distal	-5	no	19.066	19.169	PhosphoSitePlus;EPSD	TCGA;COSMIC	16.704	Up-regulation
AGC_PKC_PKCa_PRKCA_ST	Q15311	RALBP1	P17252	PRKCA	S11	E14G	14	Missense	distal	3	no	16.116	16.715	EPSD	TCGA;ICGC;COSMIC	16.704	Gain
AGC_PKC_PKCa_PRKCA_ST	Q15311	RALBP1	P17252	PRKCA	S468	E470K	470	Missense	proximal	2	no	11.516	16.795	EPSD	TCGA;ICGC;COSMIC	16.704	Gain
AGC_PKC_PKCa_PRKCA_ST	Q12809	KCNH2	P17252	PRKCA	S354	S351L	351	Missense	distal	-3	no	17.261	15.775	EPSD	TCGA;COSMIC	16.704	Loss
AGC_PKC_PKCa_PRKCA_ST	Q12809	KCNH2	P17252	PRKCA	S354	I358M	358	Missense	distal	4	no	17.261	18.756	EPSD	TCGA;COSMIC	16.704	Up-regulation
AGC_PKC_PKCa_PRKCA_ST	Q12809	KCNH2	P17252	PRKCA	S890	R893K	893	Missense	distal	3	no	27.532	26.909	PhosphoSitePlus	TCGA;COSMIC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	Q12809	KCNH2	P17252	PRKCA	S890	R892G	892	Missense	proximal	2	no	27.532	22.286	PhosphoSitePlus	TCGA;COSMIC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	Q12809	KCNH2	P17252	PRKCA	S890	S890F	890	Missense	central	0	yes	27.532	0.000	PhosphoSitePlus	TCGA;COSMIC	16.704	Loss
AGC_PKC_PKCa_PRKCA_ST	Q12809	KCNH2	P17252	PRKCA	S890	D896N	896	Missense	distal	6	no	27.532	27.447	PhosphoSitePlus	TCGA;COSMIC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	Q12809	KCNH2	P17252	PRKCA	T895	R893K	893	Missense	proximal	-2	no	21.854	20.226	EPSD	TCGA;COSMIC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	Q12809	KCNH2	P17252	PRKCA	T895	R892G	892	Missense	distal	-3	no	21.854	18.592	EPSD	TCGA;COSMIC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	Q12809	KCNH2	P17252	PRKCA	T895	S890F	890	Missense	distal	-5	no	21.854	21.957	EPSD	TCGA;COSMIC	16.704	Up-regulation
AGC_PKC_PKCa_PRKCA_ST	Q12809	KCNH2	P17252	PRKCA	T895	D896N	896	Missense	proximal	1	no	21.854	22.326	EPSD	TCGA;COSMIC	16.704	Up-regulation
AGC_PKC_PKCa_PRKCA_ST	Q12809	KCNH2	P17252	PRKCA	S960	G965A	965	Missense	distal	5	no	18.190	18.432	EPSD	TCGA;COSMIC	16.704	Up-regulation
AGC_PKC_PKCa_PRKCA_ST	Q12809	KCNH2	P17252	PRKCA	S960	R954L	954	Missense	distal	-6	no	18.190	18.051	EPSD	TCGA;COSMIC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	Q12809	KCNH2	P17252	PRKCA	S1137	R1135C	1135	Missense	proximal	-2	no	17.047	15.347	EPSD	TCGA;COSMIC	16.704	Loss
AGC_PKC_PKCa_PRKCA_ST	Q12809	KCNH2	P17252	PRKCA	S1137	E1130K	1130	Missense	distal	-7	no	17.047	17.054	EPSD	TCGA;COSMIC	16.704	Up-regulation
AGC_PKC_PKCa_PRKCA_ST	Q99418	CYTH2	P17252	PRKCA	T276	G271S	271	Missense	distal	-5	no	21.331	21.194	EPSD	TCGA;ICGC;COSMIC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	Q99418	CYTH2	P17252	PRKCA	T276	R279H	279	Missense	distal	3	no	21.331	20.619	EPSD	TCGA;COSMIC;CCLE	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	Q99418	CYTH2	P17252	PRKCA	S392	A385V	385	Missense	distal	-7	no	22.263	22.252	PhosphoSitePlus	TCGA;COSMIC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	P15336	ATF2	P17252	PRKCA	S146	E148K	148	Missense	proximal	2	no	13.190	18.469	EPSD	TCGA;COSMIC	16.704	Gain
AGC_PKC_PKCa_PRKCA_ST	P15336	ATF2	P17252	PRKCA	S340	P334A	334	Missense	distal	-6	no	19.248	19.243	EPSD	TCGA;COSMIC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	P15336	ATF2	P17252	PRKCA	S340	T339A	339	Missense	proximal	-1	no	19.248	19.068	EPSD	TCGA;COSMIC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	P15336	ATF2	P17252	PRKCA	S427	A422T	422	Missense	distal	-5	no	17.317	17.697	EPSD	TCGA;COSMIC;CCLE	16.704	Up-regulation
AGC_PKC_PKCa_PRKCA_ST	P15336	ATF2	P17252	PRKCA	S427	K425N	425	Missense	proximal	-2	no	17.317	15.748	EPSD	TCGA	16.704	Loss
AGC_PKC_PKCa_PRKCA_ST	Q9NRY4	ARHGAP35	P17252	PRKCA	S46	R44C	44	Missense	proximal	-2	no	17.404	15.704	EPSD	TCGA;ICGC;COSMIC	16.704	Loss
AGC_PKC_PKCa_PRKCA_ST	Q9NRY4	ARHGAP35	P17252	PRKCA	S46	R41H	41	Missense	distal	-5	no	17.404	17.048	EPSD	TCGA;ICGC;COSMIC;GDSC;CCLE	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	Q9NRY4	ARHGAP35	P17252	PRKCA	S46	R44H	44	Missense	proximal	-2	no	17.404	12.850	EPSD	TCGA;ICGC;COSMIC	16.704	Loss
AGC_PKC_PKCa_PRKCA_ST	Q9NRY4	ARHGAP35	P17252	PRKCA	S46	V43M	43	Missense	distal	-3	no	17.404	18.121	EPSD	TCGA;ICGC;COSMIC;GDSC;CCLE	16.704	Up-regulation
AGC_PKC_PKCa_PRKCA_ST	Q9NRY4	ARHGAP35	P17252	PRKCA	S589	R584G	584	Missense	distal	-5	no	16.949	16.659	EPSD	TCGA;ICGC;COSMIC	16.704	Loss
AGC_PKC_PKCa_PRKCA_ST	Q9NRY4	ARHGAP35	P17252	PRKCA	S589	Q586P	586	Missense	distal	-3	no	16.949	15.958	EPSD	TCGA;ICGC;COSMIC	16.704	Loss
AGC_PKC_PKCa_PRKCA_ST	Q9NRY4	ARHGAP35	P17252	PRKCA	S684	R689Q	689	Missense	distal	5	no	18.850	18.841	EPSD	TCGA	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	Q9NRY4	ARHGAP35	P17252	PRKCA	S684	D690N	690	Missense	distal	6	no	18.850	18.765	EPSD	TCGA;ICGC;COSMIC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	Q9NRY4	ARHGAP35	P17252	PRKCA	S684	N691T	691	Missense	distal	7	no	18.850	18.880	EPSD	TCGA;ICGC;COSMIC	16.704	Up-regulation
AGC_PKC_PKCa_PRKCA_ST	Q9NRY4	ARHGAP35	P17252	PRKCA	S684	R682K	682	Missense	proximal	-2	no	18.850	17.222	EPSD	TCGA;ICGC;COSMIC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	Q9NRY4	ARHGAP35	P17252	PRKCA	S684	T685M	685	Missense	proximal	1	no	18.850	19.135	EPSD	TCGA;ICGC;COSMIC;CCLE	16.704	Up-regulation
AGC_PKC_PKCa_PRKCA_ST	Q9NRY4	ARHGAP35	P17252	PRKCA	S684	G687C	687	Missense	distal	3	no	18.850	16.871	EPSD	TCGA;ICGC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	Q9NRY4	ARHGAP35	P17252	PRKCA	S684	R688W	688	Missense	distal	4	no	18.850	17.314	EPSD	TCGA;ICGC;COSMIC;CCLE	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	Q9NRY4	ARHGAP35	P17252	PRKCA	T685	R689Q	689	Missense	distal	4	no	17.614	17.397	EPSD	TCGA	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	Q9NRY4	ARHGAP35	P17252	PRKCA	T685	N691T	691	Missense	distal	6	no	17.614	17.668	EPSD	TCGA;ICGC;COSMIC	16.704	Up-regulation
AGC_PKC_PKCa_PRKCA_ST	Q9NRY4	ARHGAP35	P17252	PRKCA	T685	R682K	682	Missense	distal	-3	no	17.614	15.588	EPSD	TCGA;ICGC;COSMIC	16.704	Loss
AGC_PKC_PKCa_PRKCA_ST	Q9NRY4	ARHGAP35	P17252	PRKCA	T685	T685M	685	Missense	central	0	yes	17.614	0.000	EPSD	TCGA;ICGC;COSMIC;CCLE	16.704	Loss
AGC_PKC_PKCa_PRKCA_ST	Q9NRY4	ARHGAP35	P17252	PRKCA	T685	G687C	687	Missense	proximal	2	no	17.614	18.509	EPSD	TCGA;ICGC	16.704	Up-regulation
AGC_PKC_PKCa_PRKCA_ST	Q9NRY4	ARHGAP35	P17252	PRKCA	T685	R688W	688	Missense	distal	3	no	17.614	14.681	EPSD	TCGA;ICGC;COSMIC;CCLE	16.704	Loss
AGC_PKC_PKCa_PRKCA_ST	Q9NRY4	ARHGAP35	P17252	PRKCA	S761	R763H	763	Missense	proximal	2	no	17.696	12.673	EPSD	TCGA;ICGC;COSMIC	16.704	Loss
AGC_PKC_PKCa_PRKCA_ST	Q9NRY4	ARHGAP35	P17252	PRKCA	S761	K756N	756	Missense	distal	-5	no	17.696	17.353	EPSD	TCGA;ICGC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	Q9NRY4	ARHGAP35	P17252	PRKCA	S773	D776Y	776	Missense	distal	3	no	17.378	16.835	EPSD	TCGA;ICGC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	Q9NRY4	ARHGAP35	P17252	PRKCA	S845	R847T	847	Missense	proximal	2	no	19.980	15.170	EPSD	TCGA;ICGC;COSMIC	16.704	Loss
AGC_PKC_PKCa_PRKCA_ST	Q9NRY4	ARHGAP35	P17252	PRKCA	S845	F844S	844	Missense	proximal	-1	no	19.980	20.688	EPSD	TCGA;ICGC;COSMIC	16.704	Up-regulation
AGC_PKC_PKCa_PRKCA_ST	Q9NRY4	ARHGAP35	P17252	PRKCA	S845	R850W	850	Missense	distal	5	no	19.980	19.472	EPSD	TCGA;ICGC;COSMIC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	Q9NRY4	ARHGAP35	P17252	PRKCA	S845	H841N	841	Missense	distal	-4	no	19.980	20.032	EPSD	TCGA;ICGC;COSMIC	16.704	Up-regulation
AGC_PKC_PKCa_PRKCA_ST	Q9NRY4	ARHGAP35	P17252	PRKCA	S849	R847T	847	Missense	proximal	-2	no	17.000	14.107	EPSD	TCGA;ICGC;COSMIC	16.704	Loss
AGC_PKC_PKCa_PRKCA_ST	Q9NRY4	ARHGAP35	P17252	PRKCA	S849	G854V	854	Missense	distal	5	no	17.000	16.859	EPSD	TCGA;ICGC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	Q9NRY4	ARHGAP35	P17252	PRKCA	S849	F844S	844	Missense	distal	-5	no	17.000	16.897	EPSD	TCGA;ICGC;COSMIC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	Q9NRY4	ARHGAP35	P17252	PRKCA	S849	R850W	850	Missense	proximal	1	no	17.000	16.277	EPSD	TCGA;ICGC;COSMIC	16.704	Loss
AGC_PKC_PKCa_PRKCA_ST	Q9NRY4	ARHGAP35	P17252	PRKCA	S860	G854V	854	Missense	distal	-6	no	16.881	16.802	EPSD	TCGA;ICGC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	Q9NRY4	ARHGAP35	P17252	PRKCA	S860	S866F	866	Missense	distal	6	no	16.881	16.840	EPSD	TCGA;ICGC;COSMIC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	Q9NRY4	ARHGAP35	P17252	PRKCA	S860	R863C	863	Missense	distal	3	no	16.881	14.263	EPSD	TCGA;ICGC;COSMIC;GDSC;CCLE	16.704	Loss
AGC_PKC_PKCa_PRKCA_ST	Q9NRY4	ARHGAP35	P17252	PRKCA	S860	A861D	861	Missense	proximal	1	no	16.881	15.658	EPSD	TCGA;ICGC	16.704	Loss
AGC_PKC_PKCa_PRKCA_ST	Q9NRY4	ARHGAP35	P17252	PRKCA	S860	S866Y	866	Missense	distal	6	no	16.881	16.900	EPSD	TCGA;ICGC;COSMIC	16.704	Up-regulation
AGC_PKC_PKCa_PRKCA_ST	Q9NRY4	ARHGAP35	P17252	PRKCA	S1150	V1152A	1152	Missense	proximal	2	no	19.515	19.831	EPSD	TCGA;ICGC;COSMIC	16.704	Up-regulation
AGC_PKC_PKCa_PRKCA_ST	Q9NRY4	ARHGAP35	P17252	PRKCA	S1150	R1147H	1147	Missense	distal	-3	no	19.515	15.659	EPSD	TCGA;ICGC;COSMIC	16.704	Loss
AGC_PKC_PKCa_PRKCA_ST	Q9NRY4	ARHGAP35	P17252	PRKCA	S1170	R1172Q	1172	Missense	proximal	2	no	20.359	16.525	EPSD	TCGA;ICGC;COSMIC	16.704	Loss
AGC_PKC_PKCa_PRKCA_ST	Q9NRY4	ARHGAP35	P17252	PRKCA	S1170	S1176N	1176	Missense	distal	6	no	20.359	20.257	EPSD	TCGA;ICGC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	Q9NRY4	ARHGAP35	P17252	PRKCA	S1221	R1214Q	1214	Missense	distal	-7	no	20.552	20.544	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	Q9NRY4	ARHGAP35	P17252	PRKCA	S1221	R1215M	1215	Missense	distal	-6	no	20.552	20.476	EPSD;PhosphoSitePlus	TCGA;ICGC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	Q9NRY4	ARHGAP35	P17252	PRKCA	S1236	I1237M	1237	Missense	proximal	1	no	18.753	17.702	PhosphoSitePlus;EPSD	TCGA;ICGC;COSMIC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	Q9NRY4	ARHGAP35	P17252	PRKCA	S1236	R1234P	1234	Missense	proximal	-2	no	18.753	15.711	PhosphoSitePlus;EPSD	TCGA;ICGC;COSMIC	16.704	Loss
AGC_PKC_PKCa_PRKCA_ST	P16150	SPN	P17252	PRKCA	S351	R352L	352	Missense	proximal	1	no	23.344	22.996	PhosphoSitePlus	TCGA	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	P16150	SPN	P17252	PRKCA	S351	R349W	349	Missense	proximal	-2	no	23.344	21.347	PhosphoSitePlus	TCGA;ICGC;COSMIC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	P16150	SPN	P17252	PRKCA	S355	R352L	352	Missense	distal	-3	no	19.700	15.345	EPSD	TCGA	16.704	Loss
AGC_PKC_PKCa_PRKCA_ST	P16150	SPN	P17252	PRKCA	S355	R349W	349	Missense	distal	-6	no	19.700	19.416	EPSD	TCGA;ICGC;COSMIC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	O60716	CTNND1	P17252	PRKCA	S38	E42K	42	Missense	distal	4	no	16.412	16.951	EPSD	TCGA;ICGC;COSMIC	16.704	Gain
AGC_PKC_PKCa_PRKCA_ST	O60716	CTNND1	P17252	PRKCA	T61	R68Q	68	Missense	distal	7	no	17.197	17.193	EPSD	TCGA;COSMIC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	O60716	CTNND1	P17252	PRKCA	S244	R249W	249	Missense	distal	5	no	17.200	16.692	EPSD	TCGA;COSMIC	16.704	Loss
AGC_PKC_PKCa_PRKCA_ST	O60716	CTNND1	P17252	PRKCA	T304	M298T	298	Missense	distal	-6	no	16.978	16.856	EPSD	TCGA;COSMIC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	O60716	CTNND1	P17252	PRKCA	S320	R315G	315	Missense	distal	-5	no	18.883	18.593	EPSD	TCGA;COSMIC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	O60716	CTNND1	P17252	PRKCA	S320	L318R	318	Missense	proximal	-2	no	18.883	21.571	EPSD	TCGA;COSMIC	16.704	Up-regulation
AGC_PKC_PKCa_PRKCA_ST	O60716	CTNND1	P17252	PRKCA	S320	R317H	317	Missense	distal	-3	no	18.883	15.027	EPSD	TCGA;COSMIC	16.704	Loss
AGC_PKC_PKCa_PRKCA_ST	O60716	CTNND1	P17252	PRKCA	S352	R354H	354	Missense	proximal	2	no	20.880	15.857	EPSD	TCGA;COSMIC	16.704	Loss
AGC_PKC_PKCa_PRKCA_ST	O60716	CTNND1	P17252	PRKCA	S484	I489S	489	Missense	distal	5	no	20.140	20.333	EPSD	TCGA;COSMIC	16.704	Up-regulation
AGC_PKC_PKCa_PRKCA_ST	O60716	CTNND1	P17252	PRKCA	S484	V490M	490	Missense	distal	6	no	20.140	20.228	EPSD	TCGA;COSMIC	16.704	Up-regulation
AGC_PKC_PKCa_PRKCA_ST	O60716	CTNND1	P17252	PRKCA	S539	R545H	545	Missense	distal	6	no	19.007	18.930	EPSD	TCGA;COSMIC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	O60716	CTNND1	P17252	PRKCA	S539	R546Q	546	Missense	distal	7	no	19.007	19.003	EPSD	TCGA;COSMIC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	O60716	CTNND1	P17252	PRKCA	S587	S587P	587	Missense	central	0	yes	17.809	0.000	EPSD	TCGA;COSMIC	16.704	Loss
AGC_PKC_PKCa_PRKCA_ST	O60716	CTNND1	P17252	PRKCA	S587	R584Q	584	Missense	distal	-3	no	17.809	14.951	EPSD	TCGA;COSMIC	16.704	Loss
AGC_PKC_PKCa_PRKCA_ST	O60716	CTNND1	P17252	PRKCA	S651	P647S	647	Missense	distal	-4	no	18.881	19.052	EPSD	TCGA;COSMIC	16.704	Up-regulation
AGC_PKC_PKCa_PRKCA_ST	O60716	CTNND1	P17252	PRKCA	S651	E657D	657	Missense	distal	6	no	18.881	18.898	EPSD	TCGA;COSMIC	16.704	Up-regulation
AGC_PKC_PKCa_PRKCA_ST	O60716	CTNND1	P17252	PRKCA	S879	L872F	872	Missense	distal	-7	no	18.797	18.795	PhosphoSitePlus	TCGA;COSMIC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	O60716	CTNND1	P17252	PRKCA	S879	R885W	885	Missense	distal	6	no	18.797	18.549	PhosphoSitePlus	TCGA;COSMIC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	O60716	CTNND1	P17252	PRKCA	S879	D874N	874	Missense	distal	-5	no	18.797	18.827	PhosphoSitePlus	TCGA;COSMIC	16.704	Up-regulation
AGC_PKC_PKCa_PRKCA_ST	O60716	CTNND1	P17252	PRKCA	S879	K882T	882	Missense	distal	3	no	18.797	17.583	PhosphoSitePlus	TCGA;COSMIC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	O60716	CTNND1	P17252	PRKCA	S879	K878N	878	Missense	proximal	-1	no	18.797	18.195	PhosphoSitePlus	TCGA	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	O60716	CTNND1	P17252	PRKCA	S891	R885W	885	Missense	distal	-6	no	17.011	16.727	EPSD	TCGA;COSMIC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	Q9NQA5	TRPV5	P17252	PRKCA	S53	E55K	55	Missense	proximal	2	no	15.626	20.905	EPSD	TCGA;ICGC;COSMIC;GDSC;CCLE	16.704	Gain
AGC_PKC_PKCa_PRKCA_ST	Q9NQA5	TRPV5	P17252	PRKCA	S59	L61R	61	Missense	proximal	2	no	14.472	19.459	EPSD	TCGA;ICGC;COSMIC	16.704	Gain
AGC_PKC_PKCa_PRKCA_ST	Q9NQA5	TRPV5	P17252	PRKCA	S142	S142N	142	Missense	central	0	yes	19.851	0.000	EPSD	TCGA;ICGC;COSMIC	16.704	Loss
AGC_PKC_PKCa_PRKCA_ST	Q9NQA5	TRPV5	P17252	PRKCA	S142	T138P	138	Missense	distal	-4	no	19.851	20.341	EPSD	TCGA;ICGC;COSMIC;GDSC	16.704	Up-regulation
AGC_PKC_PKCa_PRKCA_ST	Q9NQA5	TRPV5	P17252	PRKCA	S142	T148R	148	Missense	distal	6	no	19.851	19.971	EPSD	TCGA;ICGC;COSMIC	16.704	Up-regulation
AGC_PKC_PKCa_PRKCA_ST	Q9NQA5	TRPV5	P17252	PRKCA	S142	T138N	138	Missense	distal	-4	no	19.851	20.183	EPSD	TCGA;ICGC;COSMIC	16.704	Up-regulation
AGC_PKC_PKCa_PRKCA_ST	Q9NQA5	TRPV5	P17252	PRKCA	S142	A141T	141	Missense	proximal	-1	no	19.851	20.032	EPSD	TCGA;ICGC;COSMIC	16.704	Up-regulation
AGC_PKC_PKCa_PRKCA_ST	Q9NQA5	TRPV5	P17252	PRKCA	S142	R139H	139	Missense	distal	-3	no	19.851	15.995	EPSD	TCGA;ICGC;COSMIC	16.704	Loss
AGC_PKC_PKCa_PRKCA_ST	Q9NQA5	TRPV5	P17252	PRKCA	S142	R139C	139	Missense	distal	-3	no	19.851	17.112	EPSD	TCGA;ICGC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	Q9NQA5	TRPV5	P17252	PRKCA	S155	T148R	148	Missense	distal	-7	no	22.736	22.744	EPSD	TCGA;ICGC;COSMIC	16.704	Up-regulation
AGC_PKC_PKCa_PRKCA_ST	Q9NQA5	TRPV5	P17252	PRKCA	S155	R153H	153	Missense	proximal	-2	no	22.736	18.183	EPSD	TCGA;ICGC;COSMIC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	Q9NQA5	TRPV5	P17252	PRKCA	S155	T150N	150	Missense	distal	-5	no	22.736	22.480	EPSD	TCGA;ICGC;COSMIC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	Q9NQA5	TRPV5	P17252	PRKCA	S155	R153C	153	Missense	proximal	-2	no	22.736	21.037	EPSD	TCGA;ICGC;COSMIC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	Q9NQA5	TRPV5	P17252	PRKCA	S155	P156S	156	Missense	proximal	1	no	22.736	22.337	EPSD	TCGA;ICGC;COSMIC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	Q9NQA5	TRPV5	P17252	PRKCA	S299	R302Q	302	Missense	distal	3	no	19.515	17.061	PhosphoSitePlus;EPSD	TCGA;ICGC;COSMIC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	Q9NQA5	TRPV5	P17252	PRKCA	S654	D658N	658	Missense	distal	4	no	19.496	19.138	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	Q9NQA5	TRPV5	P17252	PRKCA	S654	D658E	658	Missense	distal	4	no	19.496	19.726	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	16.704	Up-regulation
AGC_PKC_PKCa_PRKCA_ST	P43629	KIR3DL1	P17252	PRKCA	S296	F294S	294	Missense	proximal	-2	no	20.275	20.946	EPSD	TCGA;ICGC	16.704	Up-regulation
AGC_PKC_PKCa_PRKCA_ST	P43629	KIR3DL1	P17252	PRKCA	S415	R413C	413	Missense	proximal	-2	no	19.172	17.472	PhosphoSitePlus	TCGA;ICGC;COSMIC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	P43629	KIR3DL1	P17252	PRKCA	S415	P421H	421	Missense	distal	6	no	19.172	19.133	PhosphoSitePlus	TCGA;COSMIC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	P43629	KIR3DL1	P17252	PRKCA	S415	Q408K	408	Missense	distal	-7	no	19.172	19.176	PhosphoSitePlus	TCGA;COSMIC	16.704	Up-regulation
AGC_PKC_PKCa_PRKCA_ST	P43629	KIR3DL1	P17252	PRKCA	S415	R413H	413	Missense	proximal	-2	no	19.172	14.619	PhosphoSitePlus	TCGA;COSMIC	16.704	Loss
AGC_PKC_PKCa_PRKCA_ST	P43629	KIR3DL1	P17252	PRKCA	S415	T412S	412	Missense	distal	-3	no	19.172	20.466	PhosphoSitePlus	TCGA;COSMIC	16.704	Up-regulation
AGC_PKC_PKCa_PRKCA_ST	P43629	KIR3DL1	P17252	PRKCA	S415	P418H	418	Missense	distal	3	no	19.172	19.991	PhosphoSitePlus	TCGA;COSMIC	16.704	Up-regulation
AGC_PKC_PKCa_PRKCA_ST	O75955	FLOT1	P17252	PRKCA	S19	R18Q	18	Missense	proximal	-1	no	16.978	16.160	EPSD	TCGA;ICGC;COSMIC	16.704	Loss
AGC_PKC_PKCa_PRKCA_ST	O75955	FLOT1	P17252	PRKCA	S19	S14F	14	Missense	distal	-5	no	16.978	17.081	EPSD	TCGA;ICGC;COSMIC	16.704	Up-regulation
AGC_PKC_PKCa_PRKCA_ST	P08833	IGFBP1	P17252	PRKCA	S126	E128K	128	Missense	proximal	2	no	11.659	16.939	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	16.704	Gain
AGC_PKC_PKCa_PRKCA_ST	Q14315	FLNC	P17252	PRKCA	S78	R84H	84	Missense	distal	6	no	19.836	19.758	EPSD	TCGA;ICGC;COSMIC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	Q14315	FLNC	P17252	PRKCA	S78	I71T	71	Missense	distal	-7	no	19.836	19.842	EPSD	TCGA;ICGC;COSMIC	16.704	Up-regulation
AGC_PKC_PKCa_PRKCA_ST	Q14315	FLNC	P17252	PRKCA	S379	G373E	373	Missense	distal	-6	no	20.058	20.091	EPSD	TCGA;ICGC;COSMIC	16.704	Up-regulation
AGC_PKC_PKCa_PRKCA_ST	Q14315	FLNC	P17252	PRKCA	T423	R420W	420	Missense	distal	-3	no	17.935	15.581	EPSD	TCGA;ICGC;COSMIC	16.704	Loss
AGC_PKC_PKCa_PRKCA_ST	Q14315	FLNC	P17252	PRKCA	T423	R420Q	420	Missense	distal	-3	no	17.935	15.077	EPSD	TCGA;ICGC;COSMIC;GDSC	16.704	Loss
AGC_PKC_PKCa_PRKCA_ST	Q14315	FLNC	P17252	PRKCA	S480	A479P	479	Missense	proximal	-1	no	22.448	22.708	EPSD	TCGA;ICGC;COSMIC	16.704	Up-regulation
AGC_PKC_PKCa_PRKCA_ST	Q14315	FLNC	P17252	PRKCA	S480	P486H	486	Missense	distal	6	no	22.448	22.409	EPSD	TCGA;ICGC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	Q14315	FLNC	P17252	PRKCA	S480	N473S	473	Missense	distal	-7	no	22.448	22.453	EPSD	TCGA;ICGC	16.704	Up-regulation
AGC_PKC_PKCa_PRKCA_ST	Q14315	FLNC	P17252	PRKCA	S480	A479T	479	Missense	proximal	-1	no	22.448	22.629	EPSD	TCGA;ICGC;GDSC;CCLE	16.704	Up-regulation
AGC_PKC_PKCa_PRKCA_ST	Q14315	FLNC	P17252	PRKCA	T909	R916W	916	Missense	distal	7	no	18.124	17.943	EPSD	TCGA;ICGC;COSMIC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	Q14315	FLNC	P17252	PRKCA	T909	K911N	911	Missense	proximal	2	no	18.124	13.175	EPSD	TCGA;ICGC;COSMIC	16.704	Loss
AGC_PKC_PKCa_PRKCA_ST	Q14315	FLNC	P17252	PRKCA	S1005	S1005L	1005	Missense	central	0	yes	19.291	0.000	EPSD	TCGA;ICGC;COSMIC;CCLE	16.704	Loss
AGC_PKC_PKCa_PRKCA_ST	Q14315	FLNC	P17252	PRKCA	S1005	P1006T	1006	Missense	proximal	1	no	19.291	19.218	EPSD	TCGA;ICGC;COSMIC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	Q14315	FLNC	P17252	PRKCA	S1005	R1002Q	1002	Missense	distal	-3	no	19.291	16.433	EPSD	TCGA;ICGC;COSMIC;CCLE	16.704	Loss
AGC_PKC_PKCa_PRKCA_ST	Q14315	FLNC	P17252	PRKCA	S1005	L999R	999	Missense	distal	-6	no	19.291	19.429	EPSD	TCGA;ICGC	16.704	Up-regulation
AGC_PKC_PKCa_PRKCA_ST	Q14315	FLNC	P17252	PRKCA	S1005	R1009W	1009	Missense	distal	4	no	19.291	17.755	EPSD	TCGA;ICGC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	Q14315	FLNC	P17252	PRKCA	S1007	S1005L	1005	Missense	proximal	-2	no	18.149	18.763	EPSD	TCGA;ICGC;COSMIC;CCLE	16.704	Up-regulation
AGC_PKC_PKCa_PRKCA_ST	Q14315	FLNC	P17252	PRKCA	S1007	P1006T	1006	Missense	proximal	-1	no	18.149	18.071	EPSD	TCGA;ICGC;COSMIC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	Q14315	FLNC	P17252	PRKCA	S1007	R1002Q	1002	Missense	distal	-5	no	18.149	17.998	EPSD	TCGA;ICGC;COSMIC;CCLE	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	Q14315	FLNC	P17252	PRKCA	S1007	R1009W	1009	Missense	proximal	2	no	18.149	12.710	EPSD	TCGA;ICGC	16.704	Loss
AGC_PKC_PKCa_PRKCA_ST	Q14315	FLNC	P17252	PRKCA	T1087	G1089R	1089	Missense	proximal	2	no	11.773	17.018	EPSD	TCGA;ICGC;COSMIC	16.704	Gain
AGC_PKC_PKCa_PRKCA_ST	Q14315	FLNC	P17252	PRKCA	S1396	D1399N	1399	Missense	distal	3	no	16.563	16.718	EPSD	TCGA;ICGC;COSMIC	16.704	Gain
AGC_PKC_PKCa_PRKCA_ST	Q14315	FLNC	P17252	PRKCA	T1809	V1802L	1802	Missense	distal	-7	no	17.429	17.432	EPSD	TCGA;ICGC;COSMIC	16.704	Up-regulation
AGC_PKC_PKCa_PRKCA_ST	Q14315	FLNC	P17252	PRKCA	T1809	P1812A	1812	Missense	distal	3	no	17.429	17.363	EPSD	TCGA;ICGC;COSMIC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	Q14315	FLNC	P17252	PRKCA	T1809	V1802M	1802	Missense	distal	-7	no	17.429	17.440	EPSD	TCGA;ICGC;COSMIC	16.704	Up-regulation
AGC_PKC_PKCa_PRKCA_ST	Q14315	FLNC	P17252	PRKCA	T1809	G1807R	1807	Missense	proximal	-2	no	17.429	20.301	EPSD	TCGA;COSMIC	16.704	Up-regulation
AGC_PKC_PKCa_PRKCA_ST	Q14315	FLNC	P17252	PRKCA	T1809	S1806L	1806	Missense	distal	-3	no	17.429	15.944	EPSD	TCGA;COSMIC	16.704	Loss
AGC_PKC_PKCa_PRKCA_ST	Q14315	FLNC	P17252	PRKCA	T1943	I1946M	1946	Missense	distal	3	no	15.734	17.015	EPSD	TCGA;COSMIC	16.704	Gain
AGC_PKC_PKCa_PRKCA_ST	Q14315	FLNC	P17252	PRKCA	S1980	S1985L	1985	Missense	distal	5	no	17.169	16.979	EPSD	TCGA;COSMIC;GDSC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	Q14315	FLNC	P17252	PRKCA	S1980	S1975N	1975	Missense	distal	-5	no	17.169	17.240	EPSD	TCGA;COSMIC	16.704	Up-regulation
AGC_PKC_PKCa_PRKCA_ST	Q14315	FLNC	P17252	PRKCA	S1980	R1982C	1982	Missense	proximal	2	no	17.169	12.819	EPSD	TCGA;ICGC;COSMIC	16.704	Loss
AGC_PKC_PKCa_PRKCA_ST	Q14315	FLNC	P17252	PRKCA	S2016	V2017M	2017	Missense	proximal	1	no	18.009	17.670	EPSD	TCGA;ICGC;COSMIC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	Q14315	FLNC	P17252	PRKCA	S2016	R2018C	2018	Missense	proximal	2	no	18.009	13.659	EPSD	TCGA;COSMIC	16.704	Loss
AGC_PKC_PKCa_PRKCA_ST	Q14315	FLNC	P17252	PRKCA	S2016	V2017L	2017	Missense	proximal	1	no	18.009	17.884	EPSD	TCGA;ICGC;COSMIC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	Q14315	FLNC	P17252	PRKCA	S2016	K2022T	2022	Missense	distal	6	no	18.009	17.902	EPSD	TCGA;COSMIC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	Q14315	FLNC	P17252	PRKCA	S2016	R2018H	2018	Missense	proximal	2	no	18.009	12.986	EPSD	TCGA;ICGC;COSMIC	16.704	Loss
AGC_PKC_PKCa_PRKCA_ST	Q14315	FLNC	P17252	PRKCA	T2125	P2123S	2123	Missense	proximal	-2	no	17.356	17.097	EPSD	TCGA;ICGC;COSMIC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	Q14315	FLNC	P17252	PRKCA	S2137	R2133C	2133	Missense	distal	-4	no	19.341	17.998	EPSD	TCGA;ICGC;COSMIC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	Q14315	FLNC	P17252	PRKCA	S2137	R2140W	2140	Missense	distal	3	no	19.341	16.408	EPSD	TCGA;COSMIC	16.704	Loss
AGC_PKC_PKCa_PRKCA_ST	Q14315	FLNC	P17252	PRKCA	S2233	Q2240P	2240	Missense	distal	7	no	17.184	17.179	EPSD	TCGA;ICGC;COSMIC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	Q14315	FLNC	P17252	PRKCA	S2233	R2228W	2228	Missense	distal	-5	no	17.184	16.870	EPSD	TCGA;ICGC;COSMIC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	Q14315	FLNC	P17252	PRKCA	S2233	R2228Q	2228	Missense	distal	-5	no	17.184	17.032	EPSD	TCGA;COSMIC;GDSC;CCLE	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	Q14315	FLNC	P17252	PRKCA	S2233	G2227D	2227	Missense	distal	-6	no	17.184	17.134	EPSD	TCGA;COSMIC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	Q14315	FLNC	P17252	PRKCA	S2233	L2226P	2226	Missense	distal	-7	no	17.184	17.187	EPSD	TCGA;ICGC;COSMIC	16.704	Up-regulation
AGC_PKC_PKCa_PRKCA_ST	Q14315	FLNC	P17252	PRKCA	T2412	R2409C	2409	Missense	distal	-3	no	18.158	15.418	EPSD	TCGA;COSMIC	16.704	Loss
AGC_PKC_PKCa_PRKCA_ST	Q14315	FLNC	P17252	PRKCA	T2412	E2418K	2418	Missense	distal	6	no	18.158	18.252	EPSD	TCGA;COSMIC	16.704	Up-regulation
AGC_PKC_PKCa_PRKCA_ST	Q14315	FLNC	P17252	PRKCA	T2412	R2410C	2410	Missense	proximal	-2	no	18.158	16.458	EPSD	TCGA;ICGC;COSMIC;GDSC;CCLE	16.704	Loss
AGC_PKC_PKCa_PRKCA_ST	Q14315	FLNC	P17252	PRKCA	T2412	E2418D	2418	Missense	distal	6	no	18.158	18.175	EPSD	TCGA	16.704	Up-regulation
AGC_PKC_PKCa_PRKCA_ST	Q14315	FLNC	P17252	PRKCA	T2412	S2405L	2405	Missense	distal	-7	no	18.158	18.152	EPSD	TCGA;ICGC;COSMIC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	Q14315	FLNC	P17252	PRKCA	T2446	P2447R	2447	Missense	proximal	1	no	16.245	17.019	EPSD	TCGA	16.704	Gain
AGC_PKC_PKCa_PRKCA_ST	Q14315	FLNC	P17252	PRKCA	S2461	R2467C	2467	Missense	distal	6	no	16.929	16.689	EPSD	TCGA;COSMIC	16.704	Loss
AGC_PKC_PKCa_PRKCA_ST	Q14315	FLNC	P17252	PRKCA	S2619	S2626N	2626	Missense	distal	7	no	20.752	20.728	EPSD	TCGA;COSMIC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	Q14315	FLNC	P17252	PRKCA	S2623	S2626N	2626	Missense	distal	3	no	18.749	18.571	EPSD;PhosphoSitePlus	TCGA;COSMIC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	Q14315	FLNC	P17252	PRKCA	S2624	S2626N	2626	Missense	proximal	2	no	17.410	16.659	PhosphoSitePlus;EPSD	TCGA;COSMIC	16.704	Loss
AGC_PKC_PKCa_PRKCA_ST	P56537	EIF6	P17252	PRKCA	S6	R4P	4	Missense	proximal	-2	no	16.815	13.772	EPSD	TCGA;ICGC;COSMIC	16.704	Loss
AGC_PKC_PKCa_PRKCA_ST	Q06124	PTPN11	P17252	PRKCA	S140	L136H	136	Missense	distal	-4	no	17.079	17.129	EPSD	TCGA;ICGC;COSMIC	16.704	Up-regulation
AGC_PKC_PKCa_PRKCA_ST	Q06124	PTPN11	P17252	PRKCA	S140	S142N	142	Missense	proximal	2	no	17.079	16.328	EPSD	TCGA;ICGC;COSMIC;GDSC;CCLE	16.704	Loss
AGC_PKC_PKCa_PRKCA_ST	Q06124	PTPN11	P17252	PRKCA	S140	D146Y	146	Missense	distal	6	no	17.079	17.116	EPSD	TCGA;ICGC;COSMIC	16.704	Up-regulation
AGC_PKC_PKCa_PRKCA_ST	Q06124	PTPN11	P17252	PRKCA	S160	D155N	155	Missense	distal	-5	no	16.701	16.730	EPSD	TCGA;ICGC;COSMIC	16.704	Gain
AGC_PKC_PKCa_PRKCA_ST	Q06124	PTPN11	P17252	PRKCA	S160	D156N	156	Missense	distal	-4	no	16.701	17.049	EPSD	TCGA;ICGC;COSMIC	16.704	Gain
AGC_PKC_PKCa_PRKCA_ST	Q06124	PTPN11	P17252	PRKCA	S264	L262F	262	Missense	proximal	-2	no	19.360	18.075	EPSD	TCGA;ICGC;COSMIC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	Q06124	PTPN11	P17252	PRKCA	S503	Q510L	510	Missense	distal	7	no	20.150	20.111	EPSD	TCGA;ICGC;COSMIC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	Q06124	PTPN11	P17252	PRKCA	S503	Q510H	510	Missense	distal	7	no	20.150	20.083	EPSD	TCGA;ICGC;COSMIC;GDSC;CCLE	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	Q14432	PDE3A	P17252	PRKCA	S292	E299G	299	Missense	distal	7	no	18.649	18.720	PhosphoSitePlus;EPSD	TCGA;ICGC;COSMIC	16.704	Up-regulation
AGC_PKC_PKCa_PRKCA_ST	Q14432	PDE3A	P17252	PRKCA	S292	V296M	296	Missense	distal	4	no	18.649	20.021	PhosphoSitePlus;EPSD	TCGA;ICGC;COSMIC;GDSC;CCLE	16.704	Up-regulation
AGC_PKC_PKCa_PRKCA_ST	Q14432	PDE3A	P17252	PRKCA	S292	R291Q	291	Missense	proximal	-1	no	18.649	17.831	PhosphoSitePlus;EPSD	TCGA;ICGC;COSMIC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	Q14432	PDE3A	P17252	PRKCA	S292	A298V	298	Missense	distal	6	no	18.649	18.530	PhosphoSitePlus;EPSD	TCGA;ICGC;COSMIC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	Q14432	PDE3A	P17252	PRKCA	S293	E299G	299	Missense	distal	6	no	20.161	20.118	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	Q14432	PDE3A	P17252	PRKCA	S293	V296M	296	Missense	distal	3	no	20.161	20.747	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC;GDSC;CCLE	16.704	Up-regulation
AGC_PKC_PKCa_PRKCA_ST	Q14432	PDE3A	P17252	PRKCA	S293	R291Q	291	Missense	proximal	-2	no	20.161	18.402	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	Q14432	PDE3A	P17252	PRKCA	S293	A298V	298	Missense	distal	5	no	20.161	19.777	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	Q14432	PDE3A	P17252	PRKCA	S294	E299G	299	Missense	distal	5	no	17.739	17.727	EPSD	TCGA;ICGC;COSMIC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	Q14432	PDE3A	P17252	PRKCA	S294	V296M	296	Missense	proximal	2	no	17.739	18.305	EPSD	TCGA;ICGC;COSMIC;GDSC;CCLE	16.704	Up-regulation
AGC_PKC_PKCa_PRKCA_ST	Q14432	PDE3A	P17252	PRKCA	S294	S301F	301	Missense	distal	7	no	17.739	17.675	EPSD	TCGA;ICGC;COSMIC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	Q14432	PDE3A	P17252	PRKCA	S294	R291Q	291	Missense	distal	-3	no	17.739	14.881	EPSD	TCGA;ICGC;COSMIC	16.704	Loss
AGC_PKC_PKCa_PRKCA_ST	Q14432	PDE3A	P17252	PRKCA	S294	A298V	298	Missense	distal	4	no	17.739	16.401	EPSD	TCGA;ICGC;COSMIC	16.704	Loss
AGC_PKC_PKCa_PRKCA_ST	Q14432	PDE3A	P17252	PRKCA	S304	R309W	309	Missense	distal	5	no	17.721	17.213	EPSD	TCGA;ICGC;COSMIC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	Q14432	PDE3A	P17252	PRKCA	S304	H308R	308	Missense	distal	4	no	17.721	18.004	EPSD	TCGA;ICGC	16.704	Up-regulation
AGC_PKC_PKCa_PRKCA_ST	Q14432	PDE3A	P17252	PRKCA	S304	G302C	302	Missense	proximal	-2	no	17.721	18.893	EPSD	TCGA;ICGC;COSMIC	16.704	Up-regulation
AGC_PKC_PKCa_PRKCA_ST	Q14432	PDE3A	P17252	PRKCA	S304	E299G	299	Missense	distal	-5	no	17.721	17.738	EPSD	TCGA;ICGC;COSMIC	16.704	Up-regulation
AGC_PKC_PKCa_PRKCA_ST	Q14432	PDE3A	P17252	PRKCA	S304	S301F	301	Missense	distal	-3	no	17.721	17.971	EPSD	TCGA;ICGC;COSMIC	16.704	Up-regulation
AGC_PKC_PKCa_PRKCA_ST	Q14432	PDE3A	P17252	PRKCA	S304	A298V	298	Missense	distal	-6	no	17.721	17.645	EPSD	TCGA;ICGC;COSMIC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	Q14432	PDE3A	P17252	PRKCA	S305	R309W	309	Missense	distal	4	no	17.664	16.128	EPSD	TCGA;ICGC;COSMIC	16.704	Loss
AGC_PKC_PKCa_PRKCA_ST	Q14432	PDE3A	P17252	PRKCA	S305	H308R	308	Missense	distal	3	no	17.664	18.376	EPSD	TCGA;ICGC	16.704	Up-regulation
AGC_PKC_PKCa_PRKCA_ST	Q14432	PDE3A	P17252	PRKCA	S305	G302C	302	Missense	distal	-3	no	17.664	18.186	EPSD	TCGA;ICGC;COSMIC	16.704	Up-regulation
AGC_PKC_PKCa_PRKCA_ST	Q14432	PDE3A	P17252	PRKCA	S305	E299G	299	Missense	distal	-6	no	17.664	17.631	EPSD	TCGA;ICGC;COSMIC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	Q14432	PDE3A	P17252	PRKCA	S305	S301F	301	Missense	distal	-4	no	17.664	17.605	EPSD	TCGA;ICGC;COSMIC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	Q14432	PDE3A	P17252	PRKCA	S305	A298V	298	Missense	distal	-7	no	17.664	17.653	EPSD	TCGA;ICGC;COSMIC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	Q14432	PDE3A	P17252	PRKCA	S312	H308R	308	Missense	distal	-4	no	16.134	16.708	EPSD;PhosphoSitePlus	TCGA;ICGC	16.704	Gain
AGC_PKC_PKCa_PRKCA_ST	Q14432	PDE3A	P17252	PRKCA	S428	L425M	425	Missense	distal	-3	no	15.957	17.340	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	16.704	Gain
AGC_PKC_PKCa_PRKCA_ST	Q14432	PDE3A	P17252	PRKCA	S438	W441L	441	Missense	distal	3	no	16.025	16.721	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	16.704	Gain
AGC_PKC_PKCa_PRKCA_ST	Q14432	PDE3A	P17252	PRKCA	S463	S463N	463	Missense	central	0	yes	16.813	0.000	EPSD	TCGA;ICGC;COSMIC	16.704	Loss
AGC_PKC_PKCa_PRKCA_ST	Q14432	PDE3A	P17252	PRKCA	S463	V458L	458	Missense	distal	-5	no	16.813	17.249	EPSD	TCGA;ICGC;COSMIC	16.704	Up-regulation
AGC_PKC_PKCa_PRKCA_ST	Q14432	PDE3A	P17252	PRKCA	S463	R460I	460	Missense	distal	-3	no	16.813	12.326	EPSD	TCGA;ICGC;COSMIC	16.704	Loss
AGC_PKC_PKCa_PRKCA_ST	Q14432	PDE3A	P17252	PRKCA	S465	S463N	463	Missense	proximal	-2	no	21.436	21.541	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	16.704	Up-regulation
AGC_PKC_PKCa_PRKCA_ST	Q14432	PDE3A	P17252	PRKCA	S465	A471T	471	Missense	distal	6	no	21.436	21.358	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	Q14432	PDE3A	P17252	PRKCA	S465	V458L	458	Missense	distal	-7	no	21.436	21.438	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	16.704	Up-regulation
AGC_PKC_PKCa_PRKCA_ST	Q14432	PDE3A	P17252	PRKCA	S465	R460I	460	Missense	distal	-5	no	21.436	20.864	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	Q14432	PDE3A	P17252	PRKCA	S465	A471V	471	Missense	distal	6	no	21.436	21.317	EPSD;PhosphoSitePlus	TCGA;ICGC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	Q14432	PDE3A	P17252	PRKCA	S511	K506N	506	Missense	distal	-5	no	18.953	18.610	EPSD	TCGA;ICGC;COSMIC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	Q14432	PDE3A	P17252	PRKCA	S511	R512Q	512	Missense	proximal	1	no	18.953	18.836	EPSD	TCGA;ICGC;COSMIC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	Q14432	PDE3A	P17252	PRKCA	S511	A515T	515	Missense	distal	4	no	18.953	18.505	EPSD	TCGA;COSMIC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	Q14432	PDE3A	P17252	PRKCA	S511	K508E	508	Missense	distal	-3	no	18.953	16.040	EPSD	TCGA;ICGC;COSMIC	16.704	Loss
AGC_PKC_PKCa_PRKCA_ST	Q14432	PDE3A	P17252	PRKCA	S561	L559I	559	Missense	proximal	-2	no	17.658	16.758	EPSD	TCGA;ICGC;COSMIC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	Q14432	PDE3A	P17252	PRKCA	S561	L565F	565	Missense	distal	4	no	17.658	18.089	EPSD	TCGA;ICGC;COSMIC	16.704	Up-regulation
AGC_PKC_PKCa_PRKCA_ST	Q14432	PDE3A	P17252	PRKCA	S561	T566S	566	Missense	distal	5	no	17.658	17.833	EPSD	TCGA;ICGC;COSMIC	16.704	Up-regulation
AGC_PKC_PKCa_PRKCA_ST	Q14432	PDE3A	P17252	PRKCA	S593	P591T	591	Missense	proximal	-2	no	17.099	17.248	EPSD	TCGA;ICGC;COSMIC	16.704	Up-regulation
AGC_PKC_PKCa_PRKCA_ST	Q14432	PDE3A	P17252	PRKCA	S593	P597L	597	Missense	distal	4	no	17.099	16.507	EPSD	TCGA;ICGC;COSMIC	16.704	Loss
AGC_PKC_PKCa_PRKCA_ST	Q14432	PDE3A	P17252	PRKCA	S654	K652N	652	Missense	proximal	-2	no	19.438	17.869	EPSD	TCGA;ICGC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	Q14432	PDE3A	P17252	PRKCA	S654	S657I	657	Missense	distal	3	no	19.438	18.280	EPSD	TCGA;ICGC;COSMIC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	Q14432	PDE3A	P17252	PRKCA	S654	P649H	649	Missense	distal	-5	no	19.438	19.184	EPSD	TCGA;ICGC;COSMIC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	Q14432	PDE3A	P17252	PRKCA	S654	S654L	654	Missense	central	0	yes	19.438	0.000	EPSD	TCGA;ICGC;COSMIC	16.704	Loss
AGC_PKC_PKCa_PRKCA_ST	Q14432	PDE3A	P17252	PRKCA	S1060	P1061L	1061	Missense	proximal	1	no	17.940	18.367	EPSD	TCGA	16.704	Up-regulation
AGC_PKC_PKCa_PRKCA_ST	Q14432	PDE3A	P17252	PRKCA	S1060	F1066L	1066	Missense	distal	6	no	17.940	17.970	EPSD	TCGA;ICGC;COSMIC	16.704	Up-regulation
AGC_PKC_PKCa_PRKCA_ST	Q14432	PDE3A	P17252	PRKCA	S1060	K1063M	1063	Missense	distal	3	no	17.940	17.294	EPSD	TCGA;ICGC;COSMIC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	Q14432	PDE3A	P17252	PRKCA	S1060	N1058D	1058	Missense	proximal	-2	no	17.940	17.718	EPSD	TCGA;ICGC;COSMIC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	Q14432	PDE3A	P17252	PRKCA	S1060	F1066I	1066	Missense	distal	6	no	17.940	17.947	EPSD	TCGA;ICGC;COSMIC	16.704	Up-regulation
AGC_PKC_PKCa_PRKCA_ST	Q14432	PDE3A	P17252	PRKCA	S1060	E1053K	1053	Missense	distal	-7	no	17.940	17.948	EPSD	TCGA;ICGC;COSMIC	16.704	Up-regulation
AGC_PKC_PKCa_PRKCA_ST	P16671	CD36	P17252	PRKCA	T92	G89S	89	Missense	distal	-3	no	16.658	17.050	PhosphoSitePlus	TCGA;ICGC;COSMIC	16.704	Gain
AGC_PKC_PKCa_PRKCA_ST	Q8WZ42	TTN	P17252	PRKCA	S79	Y78C	78	Missense	proximal	-1	no	20.202	18.379	EPSD	TCGA;ICGC;COSMIC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	Q8WZ42	TTN	P17252	PRKCA	S79	N74K	74	Missense	distal	-5	no	20.202	20.545	EPSD	TCGA;ICGC	16.704	Up-regulation
AGC_PKC_PKCa_PRKCA_ST	Q8WZ42	TTN	P17252	PRKCA	S79	S86C	86	Missense	distal	7	no	20.202	20.025	EPSD	TCGA;ICGC;COSMIC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	Q8WZ42	TTN	P17252	PRKCA	S79	S79F	79	Missense	central	0	yes	20.202	0.000	EPSD	TCGA;ICGC;COSMIC	16.704	Loss
AGC_PKC_PKCa_PRKCA_ST	Q8WZ42	TTN	P17252	PRKCA	S79	R77Q	77	Missense	proximal	-2	no	20.202	18.443	EPSD	TCGA;ICGC;COSMIC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	Q8WZ42	TTN	P17252	PRKCA	S112	R109Q	109	Missense	distal	-3	no	17.735	14.878	EPSD	TCGA;ICGC;COSMIC	16.704	Loss
AGC_PKC_PKCa_PRKCA_ST	Q8WZ42	TTN	P17252	PRKCA	S112	S119I	119	Missense	distal	7	no	17.735	17.582	EPSD	TCGA;ICGC;COSMIC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	Q8WZ42	TTN	P17252	PRKCA	S320	L326F	326	Missense	distal	6	no	18.268	18.238	EPSD	TCGA;ICGC;COSMIC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	Q8WZ42	TTN	P17252	PRKCA	T330	L326F	326	Missense	distal	-4	no	16.940	17.313	EPSD	TCGA;ICGC;COSMIC	16.704	Up-regulation
AGC_PKC_PKCa_PRKCA_ST	Q8WZ42	TTN	P17252	PRKCA	T330	K329N	329	Missense	proximal	-1	no	16.940	16.338	EPSD	TCGA;ICGC;COSMIC	16.704	Loss
AGC_PKC_PKCa_PRKCA_ST	Q8WZ42	TTN	P17252	PRKCA	T330	R328H	328	Missense	proximal	-2	no	16.940	12.387	EPSD	TCGA;ICGC;COSMIC	16.704	Loss
AGC_PKC_PKCa_PRKCA_ST	Q8WZ42	TTN	P17252	PRKCA	S742	E739K	739	Missense	distal	-3	no	14.686	17.598	EPSD	TCGA;ICGC;COSMIC	16.704	Gain
AGC_PKC_PKCa_PRKCA_ST	Q8WZ42	TTN	P17252	PRKCA	S789	I787M	787	Missense	proximal	-2	no	15.776	17.382	EPSD	TCGA;ICGC;COSMIC	16.704	Gain
AGC_PKC_PKCa_PRKCA_ST	Q8WZ42	TTN	P17252	PRKCA	S813	R810H	810	Missense	distal	-3	no	17.059	13.203	EPSD	TCGA;ICGC;COSMIC	16.704	Loss
AGC_PKC_PKCa_PRKCA_ST	Q8WZ42	TTN	P17252	PRKCA	S813	R808C	808	Missense	distal	-5	no	17.059	16.383	EPSD	TCGA;ICGC;COSMIC	16.704	Loss
AGC_PKC_PKCa_PRKCA_ST	Q8WZ42	TTN	P17252	PRKCA	S813	S813C	813	Missense	central	0	yes	17.059	0.000	EPSD	TCGA;ICGC;COSMIC	16.704	Loss
AGC_PKC_PKCa_PRKCA_ST	Q8WZ42	TTN	P17252	PRKCA	S813	T811A	811	Missense	proximal	-2	no	17.059	16.867	EPSD	TCGA;ICGC;COSMIC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	Q8WZ42	TTN	P17252	PRKCA	S813	R810C	810	Missense	distal	-3	no	17.059	14.320	EPSD	TCGA;ICGC;COSMIC	16.704	Loss
AGC_PKC_PKCa_PRKCA_ST	Q8WZ42	TTN	P17252	PRKCA	T863	V864M	864	Missense	proximal	1	no	17.979	17.639	EPSD	TCGA;ICGC;COSMIC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	Q8WZ42	TTN	P17252	PRKCA	T863	S867G	867	Missense	distal	4	no	17.979	17.621	EPSD	TCGA;ICGC;COSMIC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	Q8WZ42	TTN	P17252	PRKCA	T863	S867R	867	Missense	distal	4	no	17.979	18.225	EPSD	TCGA;ICGC	16.704	Up-regulation
AGC_PKC_PKCa_PRKCA_ST	Q8WZ42	TTN	P17252	PRKCA	T863	E868K	868	Missense	distal	5	no	17.979	18.393	EPSD	TCGA;ICGC;COSMIC	16.704	Up-regulation
AGC_PKC_PKCa_PRKCA_ST	Q8WZ42	TTN	P17252	PRKCA	T863	A861V	861	Missense	proximal	-2	no	17.979	18.222	EPSD	TCGA;ICGC;COSMIC	16.704	Up-regulation
AGC_PKC_PKCa_PRKCA_ST	Q8WZ42	TTN	P17252	PRKCA	S1118	V1120F	1120	Missense	proximal	2	no	16.614	17.325	EPSD	TCGA;ICGC;COSMIC	16.704	Gain
AGC_PKC_PKCa_PRKCA_ST	Q8WZ42	TTN	P17252	PRKCA	S1348	L1355F	1355	Missense	distal	7	no	20.626	20.560	EPSD	TCGA;ICGC;COSMIC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	Q8WZ42	TTN	P17252	PRKCA	S1348	R1350H	1350	Missense	proximal	2	no	20.626	15.602	EPSD	TCGA;ICGC;COSMIC;GDSC;CCLE	16.704	Loss
AGC_PKC_PKCa_PRKCA_ST	Q8WZ42	TTN	P17252	PRKCA	S1348	D1344Y	1344	Missense	distal	-4	no	20.626	21.111	EPSD	TCGA	16.704	Up-regulation
AGC_PKC_PKCa_PRKCA_ST	Q8WZ42	TTN	P17252	PRKCA	S1348	P1352S	1352	Missense	distal	4	no	20.626	20.826	EPSD	TCGA;ICGC;COSMIC	16.704	Up-regulation
AGC_PKC_PKCa_PRKCA_ST	Q8WZ42	TTN	P17252	PRKCA	S1348	A1347T	1347	Missense	proximal	-1	no	20.626	20.807	EPSD	TCGA;ICGC;COSMIC;GDSC;CCLE	16.704	Up-regulation
AGC_PKC_PKCa_PRKCA_ST	Q8WZ42	TTN	P17252	PRKCA	S1348	R1350C	1350	Missense	proximal	2	no	20.626	16.276	EPSD	TCGA;ICGC;COSMIC;GDSC;CCLE	16.704	Loss
AGC_PKC_PKCa_PRKCA_ST	Q8WZ42	TTN	P17252	PRKCA	S1404	P1407S	1407	Missense	distal	3	no	17.414	17.554	EPSD	TCGA;ICGC;COSMIC	16.704	Up-regulation
AGC_PKC_PKCa_PRKCA_ST	Q8WZ42	TTN	P17252	PRKCA	S1404	S1404F	1404	Missense	central	0	yes	17.414	0.000	EPSD	TCGA;ICGC;COSMIC	16.704	Loss
AGC_PKC_PKCa_PRKCA_ST	Q8WZ42	TTN	P17252	PRKCA	S1406	R1412G	1412	Missense	distal	6	no	19.618	19.468	EPSD	TCGA;ICGC;COSMIC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	Q8WZ42	TTN	P17252	PRKCA	S1406	P1407S	1407	Missense	proximal	1	no	19.618	19.218	EPSD	TCGA;ICGC;COSMIC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	Q8WZ42	TTN	P17252	PRKCA	S1406	S1404F	1404	Missense	proximal	-2	no	19.618	18.946	EPSD	TCGA;ICGC;COSMIC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	Q8WZ42	TTN	P17252	PRKCA	S1409	R1412G	1412	Missense	distal	3	no	16.932	16.292	EPSD	TCGA;ICGC;COSMIC	16.704	Loss
AGC_PKC_PKCa_PRKCA_ST	Q8WZ42	TTN	P17252	PRKCA	S1409	P1407S	1407	Missense	proximal	-2	no	16.932	16.672	EPSD	TCGA;ICGC;COSMIC	16.704	Loss
AGC_PKC_PKCa_PRKCA_ST	Q8WZ42	TTN	P17252	PRKCA	S1409	S1404F	1404	Missense	distal	-5	no	16.932	17.035	EPSD	TCGA;ICGC;COSMIC	16.704	Up-regulation
AGC_PKC_PKCa_PRKCA_ST	Q8WZ42	TTN	P17252	PRKCA	S1409	R1416H	1416	Missense	distal	7	no	16.932	16.860	EPSD	TCGA;ICGC;COSMIC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	Q8WZ42	TTN	P17252	PRKCA	S1418	R1412G	1412	Missense	distal	-6	no	19.132	19.024	EPSD	TCGA;ICGC;COSMIC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	Q8WZ42	TTN	P17252	PRKCA	S1418	A1425E	1425	Missense	distal	7	no	19.132	19.084	EPSD	TCGA;ICGC;COSMIC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	Q8WZ42	TTN	P17252	PRKCA	S1418	R1416H	1416	Missense	proximal	-2	no	19.132	14.578	EPSD	TCGA;ICGC;COSMIC	16.704	Loss
AGC_PKC_PKCa_PRKCA_ST	Q8WZ42	TTN	P17252	PRKCA	S1418	P1419S	1419	Missense	proximal	1	no	19.132	18.732	EPSD	TCGA;ICGC;COSMIC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	Q8WZ42	TTN	P17252	PRKCA	S1423	A1425E	1425	Missense	proximal	2	no	17.149	16.147	EPSD	TCGA;ICGC;COSMIC	16.704	Loss
AGC_PKC_PKCa_PRKCA_ST	Q8WZ42	TTN	P17252	PRKCA	S1423	R1426K	1426	Missense	distal	3	no	17.149	16.526	EPSD	TCGA;ICGC;COSMIC	16.704	Loss
AGC_PKC_PKCa_PRKCA_ST	Q8WZ42	TTN	P17252	PRKCA	S1423	P1429S	1429	Missense	distal	6	no	17.149	17.116	EPSD	TCGA;ICGC;COSMIC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	Q8WZ42	TTN	P17252	PRKCA	S1423	R1416H	1416	Missense	distal	-7	no	17.149	17.142	EPSD	TCGA;ICGC;COSMIC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	Q8WZ42	TTN	P17252	PRKCA	S1423	P1419S	1419	Missense	distal	-4	no	17.149	17.320	EPSD	TCGA;ICGC;COSMIC	16.704	Up-regulation
AGC_PKC_PKCa_PRKCA_ST	Q8WZ42	TTN	P17252	PRKCA	S1423	R1426S	1426	Missense	distal	3	no	17.149	15.758	EPSD	TCGA;ICGC;COSMIC	16.704	Loss
AGC_PKC_PKCa_PRKCA_ST	Q8WZ42	TTN	P17252	PRKCA	S1428	A1425E	1425	Missense	distal	-3	no	19.125	18.635	EPSD	TCGA;ICGC;COSMIC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	Q8WZ42	TTN	P17252	PRKCA	S1428	R1426K	1426	Missense	proximal	-2	no	19.125	17.497	EPSD	TCGA;ICGC;COSMIC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	Q8WZ42	TTN	P17252	PRKCA	S1428	P1429S	1429	Missense	proximal	1	no	19.125	18.726	EPSD	TCGA;ICGC;COSMIC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	Q8WZ42	TTN	P17252	PRKCA	S1428	R1426S	1426	Missense	proximal	-2	no	19.125	15.823	EPSD	TCGA;ICGC;COSMIC	16.704	Loss
AGC_PKC_PKCa_PRKCA_ST	Q8WZ42	TTN	P17252	PRKCA	S1428	R1431W	1431	Missense	distal	3	no	19.125	16.191	EPSD	TCGA;ICGC;COSMIC	16.704	Loss
AGC_PKC_PKCa_PRKCA_ST	Q8WZ42	TTN	P17252	PRKCA	S1433	P1439H	1439	Missense	distal	6	no	17.000	16.961	EPSD	TCGA;ICGC;COSMIC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	Q8WZ42	TTN	P17252	PRKCA	S1433	R1426K	1426	Missense	distal	-7	no	17.000	16.995	EPSD	TCGA;ICGC;COSMIC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	Q8WZ42	TTN	P17252	PRKCA	S1433	G1440E	1440	Missense	distal	7	no	17.000	16.929	EPSD	TCGA;ICGC;COSMIC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	Q8WZ42	TTN	P17252	PRKCA	S1433	P1429S	1429	Missense	distal	-4	no	17.000	17.171	EPSD	TCGA;ICGC;COSMIC	16.704	Up-regulation
AGC_PKC_PKCa_PRKCA_ST	Q8WZ42	TTN	P17252	PRKCA	S1433	R1426S	1426	Missense	distal	-7	no	17.000	16.995	EPSD	TCGA;ICGC;COSMIC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	Q8WZ42	TTN	P17252	PRKCA	S1433	R1431W	1431	Missense	proximal	-2	no	17.000	15.002	EPSD	TCGA;ICGC;COSMIC	16.704	Loss
AGC_PKC_PKCa_PRKCA_ST	Q8WZ42	TTN	P17252	PRKCA	S1465	V1464L	1464	Missense	proximal	-1	no	16.131	17.174	EPSD	TCGA;ICGC;COSMIC	16.704	Gain
AGC_PKC_PKCa_PRKCA_ST	Q8WZ42	TTN	P17252	PRKCA	S1540	V1543E	1543	Missense	distal	3	no	18.905	19.521	EPSD	TCGA;ICGC;COSMIC	16.704	Up-regulation
AGC_PKC_PKCa_PRKCA_ST	Q8WZ42	TTN	P17252	PRKCA	S1540	T1546I	1546	Missense	distal	6	no	18.905	18.919	EPSD	TCGA;ICGC;COSMIC	16.704	Up-regulation
AGC_PKC_PKCa_PRKCA_ST	Q8WZ42	TTN	P17252	PRKCA	S1540	S1542L	1542	Missense	proximal	2	no	18.905	18.538	EPSD	TCGA;ICGC;COSMIC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	Q8WZ42	TTN	P17252	PRKCA	S1540	G1537D	1537	Missense	distal	-3	no	18.905	17.125	EPSD	TCGA;ICGC;COSMIC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	Q8WZ42	TTN	P17252	PRKCA	S1540	I1544T	1544	Missense	distal	4	no	18.905	19.918	EPSD	TCGA;ICGC;COSMIC	16.704	Up-regulation
AGC_PKC_PKCa_PRKCA_ST	Q8WZ42	TTN	P17252	PRKCA	S1540	V1547M	1547	Missense	distal	7	no	18.905	18.972	EPSD	TCGA;ICGC;COSMIC	16.704	Up-regulation
AGC_PKC_PKCa_PRKCA_ST	Q8WZ42	TTN	P17252	PRKCA	S1540	V1543A	1543	Missense	distal	3	no	18.905	19.161	EPSD	TCGA;ICGC	16.704	Up-regulation
AGC_PKC_PKCa_PRKCA_ST	Q8WZ42	TTN	P17252	PRKCA	S1540	R1535M	1535	Missense	distal	-5	no	18.905	18.738	EPSD	TCGA;ICGC;COSMIC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	Q8WZ42	TTN	P17252	PRKCA	T1986	E1988K	1988	Missense	proximal	2	no	11.953	17.232	EPSD	TCGA;ICGC;COSMIC	16.704	Gain
AGC_PKC_PKCa_PRKCA_ST	Q8WZ42	TTN	P17252	PRKCA	T2063	T2060K	2060	Missense	distal	-3	no	15.242	17.379	EPSD	TCGA;ICGC	16.704	Gain
AGC_PKC_PKCa_PRKCA_ST	Q8WZ42	TTN	P17252	PRKCA	S2316	Q2321E	2321	Missense	distal	5	no	18.161	17.900	EPSD	TCGA;ICGC;COSMIC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	Q8WZ42	TTN	P17252	PRKCA	S2316	Q2321R	2321	Missense	distal	5	no	18.161	18.170	EPSD	TCGA;ICGC;COSMIC	16.704	Up-regulation
AGC_PKC_PKCa_PRKCA_ST	Q8WZ42	TTN	P17252	PRKCA	S2316	R2317H	2317	Missense	proximal	1	no	18.161	17.348	EPSD	TCGA;ICGC;COSMIC;GDSC;CCLE	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	Q8WZ42	TTN	P17252	PRKCA	S2316	R2318H	2318	Missense	proximal	2	no	18.161	13.138	EPSD	TCGA;ICGC;COSMIC;GDSC;CCLE	16.704	Loss
AGC_PKC_PKCa_PRKCA_ST	Q8WZ42	TTN	P17252	PRKCA	S2316	R2317L	2317	Missense	proximal	1	no	18.161	17.814	EPSD	TCGA;ICGC;COSMIC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	Q8WZ42	TTN	P17252	PRKCA	S2316	R2317C	2317	Missense	proximal	1	no	18.161	15.325	EPSD	TCGA;ICGC;COSMIC	16.704	Loss
AGC_PKC_PKCa_PRKCA_ST	Q8WZ42	TTN	P17252	PRKCA	S2398	G2392V	2392	Missense	distal	-6	no	16.997	16.917	EPSD	TCGA;ICGC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	Q8WZ42	TTN	P17252	PRKCA	S2398	Q2396L	2396	Missense	proximal	-2	no	16.997	16.068	EPSD	TCGA;ICGC;COSMIC	16.704	Loss
AGC_PKC_PKCa_PRKCA_ST	Q8WZ42	TTN	P17252	PRKCA	S2437	P2430A	2430	Missense	distal	-7	no	17.226	17.231	EPSD	TCGA;ICGC;COSMIC	16.704	Up-regulation
AGC_PKC_PKCa_PRKCA_ST	Q8WZ42	TTN	P17252	PRKCA	S2437	L2432F	2432	Missense	distal	-5	no	17.226	17.030	EPSD	TCGA;ICGC;COSMIC;GDSC;CCLE	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	Q8WZ42	TTN	P17252	PRKCA	T2695	V2693A	2693	Missense	proximal	-2	no	17.338	17.094	EPSD	TCGA;ICGC;COSMIC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	Q8WZ42	TTN	P17252	PRKCA	T2695	T2698A	2698	Missense	distal	3	no	17.338	17.576	EPSD	TCGA;ICGC	16.704	Up-regulation
AGC_PKC_PKCa_PRKCA_ST	Q8WZ42	TTN	P17252	PRKCA	T2695	K2701N	2701	Missense	distal	6	no	17.338	17.176	EPSD	TCGA;ICGC;COSMIC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	Q8WZ42	TTN	P17252	PRKCA	T2695	A2700T	2700	Missense	distal	5	no	17.338	17.059	EPSD	TCGA;ICGC;COSMIC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	Q8WZ42	TTN	P17252	PRKCA	T2695	K2692N	2692	Missense	distal	-3	no	17.338	15.137	EPSD	TCGA;ICGC;COSMIC	16.704	Loss
AGC_PKC_PKCa_PRKCA_ST	Q8WZ42	TTN	P17252	PRKCA	T2695	K2701R	2701	Missense	distal	6	no	17.338	17.350	EPSD	TCGA;ICGC;COSMIC	16.704	Up-regulation
AGC_PKC_PKCa_PRKCA_ST	Q8WZ42	TTN	P17252	PRKCA	S2749	E2751K	2751	Missense	proximal	2	no	11.887	17.166	EPSD	TCGA;ICGC;COSMIC	16.704	Gain
AGC_PKC_PKCa_PRKCA_ST	Q8WZ42	TTN	P17252	PRKCA	S2763	S2756C	2756	Missense	distal	-7	no	17.684	17.670	EPSD	TCGA	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	Q8WZ42	TTN	P17252	PRKCA	S2831	E2833K	2833	Missense	proximal	2	no	13.118	18.397	EPSD	TCGA;ICGC;COSMIC	16.704	Gain
AGC_PKC_PKCa_PRKCA_ST	Q8WZ42	TTN	P17252	PRKCA	S3118	G3125R	3125	Missense	distal	7	no	16.900	16.924	EPSD	TCGA;ICGC;COSMIC	16.704	Up-regulation
AGC_PKC_PKCa_PRKCA_ST	Q8WZ42	TTN	P17252	PRKCA	S3118	M3121I	3121	Missense	distal	3	no	16.900	15.619	EPSD	TCGA;ICGC;COSMIC	16.704	Loss
AGC_PKC_PKCa_PRKCA_ST	Q8WZ42	TTN	P17252	PRKCA	S3122	G3125R	3125	Missense	distal	3	no	16.446	17.085	EPSD	TCGA;ICGC;COSMIC	16.704	Gain
AGC_PKC_PKCa_PRKCA_ST	Q8WZ42	TTN	P17252	PRKCA	S4196	S4196L	4196	Missense	central	0	yes	18.347	0.000	EPSD	TCGA;ICGC;COSMIC	16.704	Loss
AGC_PKC_PKCa_PRKCA_ST	Q8WZ42	TTN	P17252	PRKCA	S4486	T4489K	4489	Missense	distal	3	no	18.333	19.547	EPSD	TCGA;COSMIC	16.704	Up-regulation
AGC_PKC_PKCa_PRKCA_ST	Q8WZ42	TTN	P17252	PRKCA	S5404	S5400Y	5400	Missense	distal	-4	no	18.159	17.965	EPSD	TCGA	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	Q8WZ42	TTN	P17252	PRKCA	S13707	V13700A	13700	Missense	distal	-7	no	19.302	19.312	EPSD	TCGA;COSMIC	16.704	Up-regulation
AGC_PKC_PKCa_PRKCA_ST	Q8WZ42	TTN	P17252	PRKCA	S14680	S14683R	14683	Missense	distal	3	no	17.367	18.758	EPSD	TCGA;COSMIC	16.704	Up-regulation
AGC_PKC_PKCa_PRKCA_ST	Q8WZ42	TTN	P17252	PRKCA	S14680	S14683T	14683	Missense	distal	3	no	17.367	16.921	EPSD	TCGA;COSMIC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	Q8WZ42	TTN	P17252	PRKCA	T15361	K15355M	15355	Missense	distal	-6	no	18.033	17.964	EPSD	TCGA;COSMIC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	Q8WZ42	TTN	P17252	PRKCA	S17929	D17928E	17928	Missense	proximal	-1	no	17.848	18.362	EPSD	TCGA;COSMIC	16.704	Up-regulation
AGC_PKC_PKCa_PRKCA_ST	Q8WZ42	TTN	P17252	PRKCA	S19081	V19077A	19077	Missense	distal	-4	no	20.524	21.083	EPSD	TCGA	16.704	Up-regulation
AGC_PKC_PKCa_PRKCA_ST	Q8WZ42	TTN	P17252	PRKCA	T21769	D21768N	21768	Missense	proximal	-1	no	17.390	17.728	EPSD	TCGA;COSMIC	16.704	Up-regulation
AGC_PKC_PKCa_PRKCA_ST	Q8WZ42	TTN	P17252	PRKCA	T21769	K21771N	21771	Missense	proximal	2	no	17.390	12.441	EPSD	TCGA;CCLE	16.704	Loss
AGC_PKC_PKCa_PRKCA_ST	Q8WZ42	TTN	P17252	PRKCA	S23279	E23285K	23285	Missense	distal	6	no	17.437	17.531	EPSD	TCGA;ICGC;COSMIC	16.704	Up-regulation
AGC_PKC_PKCa_PRKCA_ST	Q8WZ42	TTN	P17252	PRKCA	S24704	S24698N	24698	Missense	distal	-6	no	18.327	18.270	EPSD	TCGA;COSMIC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	Q8WZ42	TTN	P17252	PRKCA	S24704	S24698G	24698	Missense	distal	-6	no	18.327	18.293	EPSD	TCGA;COSMIC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	Q8WZ42	TTN	P17252	PRKCA	S26380	L26379V	26379	Missense	proximal	-1	no	17.875	16.832	EPSD	TCGA;COSMIC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	Q8WZ42	TTN	P17252	PRKCA	T29272	G29271C	29271	Missense	proximal	-1	no	16.908	14.387	EPSD	TCGA	16.704	Loss
AGC_PKC_PKCa_PRKCA_ST	Q8WZ42	TTN	P17252	PRKCA	S29301	Y29308C	29308	Missense	distal	7	no	17.050	16.879	EPSD	TCGA;COSMIC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	Q8WZ42	TTN	P17252	PRKCA	S29421	S29418F	29418	Missense	distal	-3	no	17.037	17.287	EPSD	TCGA;COSMIC	16.704	Up-regulation
AGC_PKC_PKCa_PRKCA_ST	Q8WZ42	TTN	P17252	PRKCA	S29710	Q29716R	29716	Missense	distal	6	no	16.860	16.983	EPSD	TCGA;COSMIC	16.704	Up-regulation
AGC_PKC_PKCa_PRKCA_ST	Q8WZ42	TTN	P17252	PRKCA	S29721	Q29716R	29716	Missense	distal	-5	no	19.457	19.609	EPSD	TCGA;COSMIC	16.704	Up-regulation
AGC_PKC_PKCa_PRKCA_ST	Q8WZ42	TTN	P17252	PRKCA	S29785	S29785F	29785	Missense	central	0	yes	19.319	0.000	EPSD	TCGA;COSMIC	16.704	Loss
AGC_PKC_PKCa_PRKCA_ST	Q8WZ42	TTN	P17252	PRKCA	S30450	K30453T	30453	Missense	distal	3	no	17.410	16.196	EPSD	TCGA;COSMIC	16.704	Loss
AGC_PKC_PKCa_PRKCA_ST	Q8WZ42	TTN	P17252	PRKCA	S30709	V30712A	30712	Missense	distal	3	no	19.787	20.043	EPSD	TCGA;COSMIC	16.704	Up-regulation
AGC_PKC_PKCa_PRKCA_ST	Q8WZ42	TTN	P17252	PRKCA	S31449	L31454F	31454	Missense	distal	5	no	20.611	20.836	EPSD	TCGA;COSMIC	16.704	Up-regulation
AGC_PKC_PKCa_PRKCA_ST	Q8WZ42	TTN	P17252	PRKCA	S32478	G32481R	32481	Missense	distal	3	no	18.634	19.273	EPSD	TCGA;COSMIC;CCLE	16.704	Up-regulation
AGC_PKC_PKCa_PRKCA_ST	Q8WZ42	TTN	P17252	PRKCA	S33201	L33202P	33202	Missense	proximal	1	no	18.473	18.046	EPSD	TCGA	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	Q8WZ42	TTN	P17252	PRKCA	S34108	S34112T	34112	Missense	distal	4	no	17.096	16.665	EPSD	TCGA	16.704	Loss
AGC_PKC_PKCa_PRKCA_ST	P49841	GSK3B	P17252	PRKCA	S13	Q19R	19	Missense	distal	6	no	17.093	17.216	EPSD	TCGA	16.704	Up-regulation
AGC_PKC_PKCa_PRKCA_ST	P49841	GSK3B	P17252	PRKCA	S21	Q19R	19	Missense	proximal	-2	no	17.906	19.665	EPSD	TCGA	16.704	Up-regulation
AGC_PKC_PKCa_PRKCA_ST	P49841	GSK3B	P17252	PRKCA	S21	S25N	25	Missense	distal	4	no	17.906	17.196	EPSD	TCGA;ICGC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	P49841	GSK3B	P17252	PRKCA	S21	A22S	22	Missense	proximal	1	no	17.906	17.108	EPSD	TCGA;ICGC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	P49841	GSK3B	P17252	PRKCA	S25	Q19R	19	Missense	distal	-6	no	17.924	18.067	EPSD	TCGA	16.704	Up-regulation
AGC_PKC_PKCa_PRKCA_ST	P49841	GSK3B	P17252	PRKCA	S25	S25N	25	Missense	central	0	yes	17.924	0.000	EPSD	TCGA;ICGC	16.704	Loss
AGC_PKC_PKCa_PRKCA_ST	P49841	GSK3B	P17252	PRKCA	S25	A22S	22	Missense	distal	-3	no	17.924	19.503	EPSD	TCGA;ICGC	16.704	Up-regulation
AGC_PKC_PKCa_PRKCA_ST	P49841	GSK3B	P17252	PRKCA	S147	R148G	148	Missense	proximal	1	no	17.546	16.593	EPSD	TCGA;ICGC;COSMIC	16.704	Loss
AGC_PKC_PKCa_PRKCA_ST	P35579	MYH9	P17252	PRKCA	S36	D37H	37	Missense	proximal	1	no	19.356	20.142	EPSD	TCGA;ICGC;COSMIC	16.704	Up-regulation
AGC_PKC_PKCa_PRKCA_ST	P35579	MYH9	P17252	PRKCA	S197	A195V	195	Missense	proximal	-2	no	17.215	17.458	EPSD	TCGA;ICGC;COSMIC	16.704	Up-regulation
AGC_PKC_PKCa_PRKCA_ST	P35579	MYH9	P17252	PRKCA	S197	A192V	192	Missense	distal	-5	no	17.215	17.130	EPSD	TCGA;ICGC;COSMIC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	P35579	MYH9	P17252	PRKCA	S232	S233F	233	Missense	proximal	1	no	16.213	17.697	EPSD	TCGA;ICGC;COSMIC	16.704	Gain
AGC_PKC_PKCa_PRKCA_ST	P35579	MYH9	P17252	PRKCA	T638	R639W	639	Missense	proximal	1	no	16.837	16.113	EPSD	TCGA;ICGC;COSMIC	16.704	Loss
AGC_PKC_PKCa_PRKCA_ST	P35579	MYH9	P17252	PRKCA	T638	R639Q	639	Missense	proximal	1	no	16.837	16.720	EPSD	TCGA;ICGC;COSMIC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	P35579	MYH9	P17252	PRKCA	S1017	E1013K	1013	Missense	distal	-4	no	16.545	17.276	EPSD	TCGA;ICGC;COSMIC	16.704	Gain
AGC_PKC_PKCa_PRKCA_ST	P35579	MYH9	P17252	PRKCA	S1122	E1115K	1115	Missense	distal	-7	no	17.484	17.491	EPSD	TCGA;ICGC;COSMIC	16.704	Up-regulation
AGC_PKC_PKCa_PRKCA_ST	P35579	MYH9	P17252	PRKCA	S1126	E1131Q	1131	Missense	distal	5	no	17.515	17.776	EPSD	TCGA;ICGC;COSMIC	16.704	Up-regulation
AGC_PKC_PKCa_PRKCA_ST	P35579	MYH9	P17252	PRKCA	S1126	E1131V	1131	Missense	distal	5	no	17.515	17.362	EPSD	TCGA;ICGC;COSMIC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	P35579	MYH9	P17252	PRKCA	S1126	E1131K	1131	Missense	distal	5	no	17.515	17.929	EPSD	TCGA;ICGC;COSMIC	16.704	Up-regulation
AGC_PKC_PKCa_PRKCA_ST	P35579	MYH9	P17252	PRKCA	S1290	G1287R	1287	Missense	distal	-3	no	14.642	17.904	EPSD	TCGA;ICGC;COSMIC	16.704	Gain
AGC_PKC_PKCa_PRKCA_ST	P35579	MYH9	P17252	PRKCA	S1340	E1347K	1347	Missense	distal	7	no	18.230	18.376	EPSD	TCGA;ICGC;COSMIC	16.704	Up-regulation
AGC_PKC_PKCa_PRKCA_ST	P35579	MYH9	P17252	PRKCA	S1340	E1337K	1337	Missense	distal	-3	no	18.230	21.143	EPSD	TCGA;ICGC;COSMIC	16.704	Up-regulation
AGC_PKC_PKCa_PRKCA_ST	P35579	MYH9	P17252	PRKCA	S1340	R1342W	1342	Missense	proximal	2	no	18.230	12.791	EPSD	TCGA;ICGC;COSMIC	16.704	Loss
AGC_PKC_PKCa_PRKCA_ST	P35579	MYH9	P17252	PRKCA	S1340	S1340P	1340	Missense	central	0	yes	18.230	0.000	EPSD	TCGA;ICGC	16.704	Loss
AGC_PKC_PKCa_PRKCA_ST	P35579	MYH9	P17252	PRKCA	S1398	E1402K	1402	Missense	distal	4	no	16.207	16.746	EPSD	TCGA;ICGC;COSMIC	16.704	Gain
AGC_PKC_PKCa_PRKCA_ST	P35579	MYH9	P17252	PRKCA	S1480	L1485P	1485	Missense	distal	5	no	17.106	17.456	EPSD	TCGA;ICGC;COSMIC	16.704	Up-regulation
AGC_PKC_PKCa_PRKCA_ST	P35579	MYH9	P17252	PRKCA	S1480	R1483W	1483	Missense	distal	3	no	17.106	14.173	EPSD	TCGA;ICGC;COSMIC	16.704	Loss
AGC_PKC_PKCa_PRKCA_ST	P35579	MYH9	P17252	PRKCA	S1511	K1518N	1518	Missense	distal	7	no	17.674	17.553	EPSD	TCGA;ICGC;COSMIC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	P35579	MYH9	P17252	PRKCA	S1511	S1512F	1512	Missense	proximal	1	no	17.674	19.158	EPSD	TCGA;ICGC;COSMIC	16.704	Up-regulation
AGC_PKC_PKCa_PRKCA_ST	P35579	MYH9	P17252	PRKCA	S1526	E1531V	1531	Missense	distal	5	no	17.059	16.907	EPSD	TCGA;ICGC;COSMIC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	P35579	MYH9	P17252	PRKCA	S1526	Q1532R	1532	Missense	distal	6	no	17.059	17.182	EPSD	TCGA;ICGC	16.704	Up-regulation
AGC_PKC_PKCa_PRKCA_ST	P35579	MYH9	P17252	PRKCA	S1526	E1522K	1522	Missense	distal	-4	no	17.059	17.791	EPSD	TCGA;ICGC;COSMIC	16.704	Up-regulation
AGC_PKC_PKCa_PRKCA_ST	P35579	MYH9	P17252	PRKCA	S1606	A1608S	1608	Missense	proximal	2	no	17.030	17.108	EPSD	TCGA;ICGC;COSMIC	16.704	Up-regulation
AGC_PKC_PKCa_PRKCA_ST	P35579	MYH9	P17252	PRKCA	S1606	R1605L	1605	Missense	proximal	-1	no	17.030	16.223	EPSD	TCGA;ICGC;COSMIC	16.704	Loss
AGC_PKC_PKCa_PRKCA_ST	P35579	MYH9	P17252	PRKCA	S1606	S1606L	1606	Missense	central	0	yes	17.030	0.000	EPSD	TCGA;ICGC;COSMIC	16.704	Loss
AGC_PKC_PKCa_PRKCA_ST	P35579	MYH9	P17252	PRKCA	S1677	E1681K	1681	Missense	distal	4	no	16.840	17.379	EPSD	TCGA;ICGC;COSMIC	16.704	Up-regulation
AGC_PKC_PKCa_PRKCA_ST	P35579	MYH9	P17252	PRKCA	S1869	Q1864P	1864	Missense	distal	-5	no	17.616	17.666	EPSD	TCGA;ICGC;COSMIC	16.704	Up-regulation
AGC_PKC_PKCa_PRKCA_ST	P35579	MYH9	P17252	PRKCA	S1892	R1898C	1898	Missense	distal	6	no	17.709	17.470	EPSD	TCGA;ICGC;COSMIC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	P35579	MYH9	P17252	PRKCA	S1892	A1891T	1891	Missense	proximal	-1	no	17.709	17.890	EPSD	TCGA;ICGC;COSMIC;GDSC;CCLE	16.704	Up-regulation
AGC_PKC_PKCa_PRKCA_ST	P35579	MYH9	P17252	PRKCA	S1916	R1912H	1912	Missense	distal	-4	no	18.869	18.294	PhosphoSitePlus	TCGA;ICGC;COSMIC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	P35579	MYH9	P17252	PRKCA	S1916	S1916F	1916	Missense	central	0	yes	18.869	0.000	PhosphoSitePlus	TCGA;ICGC;COSMIC	16.704	Loss
AGC_PKC_PKCa_PRKCA_ST	P35579	MYH9	P17252	PRKCA	S1916	M1910I	1910	Missense	distal	-6	no	18.869	18.775	PhosphoSitePlus	TCGA;ICGC;COSMIC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	P35579	MYH9	P17252	PRKCA	S1916	A1909V	1909	Missense	distal	-7	no	18.869	18.858	PhosphoSitePlus	TCGA;ICGC;COSMIC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	P17812	CTPS1	P17252	PRKCA	S200	R205K	205	Missense	distal	5	no	19.253	19.397	EPSD	TCGA;COSMIC;GDSC;CCLE	16.704	Up-regulation
AGC_PKC_PKCa_PRKCA_ST	P17812	CTPS1	P17252	PRKCA	S225	M232T	232	Missense	distal	7	no	17.845	17.841	EPSD	TCGA;COSMIC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	P17812	CTPS1	P17252	PRKCA	S225	E228D	228	Missense	distal	3	no	17.845	17.359	EPSD	TCGA;COSMIC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	P17812	CTPS1	P17252	PRKCA	T455	R454K	454	Missense	proximal	-1	no	18.711	18.768	PhosphoSitePlus;EPSD	TCGA;ICGC;COSMIC	16.704	Up-regulation
AGC_PKC_PKCa_PRKCA_ST	P17812	CTPS1	P17252	PRKCA	T455	F457L	457	Missense	proximal	2	no	18.711	18.027	PhosphoSitePlus;EPSD	TCGA;COSMIC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	P17812	CTPS1	P17252	PRKCA	S462	F457L	457	Missense	distal	-5	no	16.508	16.704	EPSD;PhosphoSitePlus	TCGA;COSMIC	16.704	Gain
AGC_PKC_PKCa_PRKCA_ST	P17812	CTPS1	P17252	PRKCA	S562	T566I	566	Missense	distal	4	no	20.243	19.230	EPSD	TCGA;ICGC;COSMIC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	Q16658	FSCN1	P17252	PRKCA	S39	W46R	46	Missense	distal	7	no	20.677	20.858	PhosphoSitePlus	TCGA	16.704	Up-regulation
AGC_PKC_PKCa_PRKCA_ST	Q16658	FSCN1	P17252	PRKCA	S39	A35V	35	Missense	distal	-4	no	20.677	20.118	PhosphoSitePlus	TCGA;ICGC;COSMIC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	Q16658	FSCN1	P17252	PRKCA	S39	K43R	43	Missense	distal	4	no	20.677	20.506	PhosphoSitePlus	TCGA;ICGC;COSMIC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	Q16658	FSCN1	P17252	PRKCA	S39	I45N	45	Missense	distal	6	no	20.677	20.609	PhosphoSitePlus	TCGA;ICGC;COSMIC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	Q16658	FSCN1	P17252	PRKCA	S187	Q189H	189	Missense	proximal	2	no	17.746	16.557	EPSD	TCGA;ICGC;COSMIC	16.704	Loss
AGC_PKC_PKCa_PRKCA_ST	Q16658	FSCN1	P17252	PRKCA	S187	A180V	180	Missense	distal	-7	no	17.746	17.736	EPSD	TCGA;ICGC;COSMIC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	Q16658	FSCN1	P17252	PRKCA	T302	D301N	301	Missense	proximal	-1	no	16.370	16.708	EPSD	TCGA;COSMIC;GDSC;CCLE	16.704	Gain
AGC_PKC_PKCa_PRKCA_ST	O00168	FXYD1	P17252	PRKCA	S83	R85H	85	Missense	proximal	2	no	20.721	15.698	EPSD	TCGA;ICGC;COSMIC	16.704	Loss
AGC_PKC_PKCa_PRKCA_ST	O00168	FXYD1	P17252	PRKCA	S88	R85H	85	Missense	distal	-3	no	22.299	18.443	PhosphoSitePlus	TCGA;ICGC;COSMIC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	O00168	FXYD1	P17252	PRKCA	T89	R85H	85	Missense	distal	-4	no	18.283	17.709	EPSD	TCGA;ICGC;COSMIC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	Q15717	ELAVL1	P17252	PRKCA	T118	Q119H	119	Missense	proximal	1	no	20.443	19.747	EPSD	TCGA;ICGC;COSMIC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	Q15717	ELAVL1	P17252	PRKCA	T118	G112V	112	Missense	distal	-6	no	20.443	20.364	EPSD	TCGA;ICGC;COSMIC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	Q15717	ELAVL1	P17252	PRKCA	T118	V122L	122	Missense	distal	4	no	20.443	20.973	EPSD	TCGA;ICGC;COSMIC	16.704	Up-regulation
AGC_PKC_PKCa_PRKCA_ST	Q15717	ELAVL1	P17252	PRKCA	T118	P114L	114	Missense	distal	-4	no	20.443	20.184	EPSD	TCGA;ICGC;COSMIC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	Q15717	ELAVL1	P17252	PRKCA	S202	H201Q	201	Missense	proximal	-1	no	17.216	16.722	EPSD	TCGA;ICGC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	Q15717	ELAVL1	P17252	PRKCA	S221	R217T	217	Missense	distal	-4	no	18.232	17.377	PhosphoSitePlus;EPSD	TCGA;ICGC;COSMIC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	Q15717	ELAVL1	P17252	PRKCA	S221	D226N	226	Missense	distal	5	no	18.232	18.231	PhosphoSitePlus;EPSD	TCGA;ICGC;COSMIC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	P07355	ANXA2	P17252	PRKCA	S26	K28M	28	Missense	proximal	2	no	17.978	13.951	PhosphoSitePlus;EPSD	TCGA;COSMIC	16.704	Loss
AGC_PKC_PKCa_PRKCA_ST	Q9UQ80	PA2G4	P17252	PRKCA	S252	P251L	251	Missense	proximal	-1	no	17.758	17.639	EPSD	TCGA;ICGC;COSMIC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	Q9UQ80	PA2G4	P17252	PRKCA	S252	T245I	245	Missense	distal	-7	no	17.758	17.752	EPSD	TCGA;ICGC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	Q9UQ80	PA2G4	P17252	PRKCA	S335	P337R	337	Missense	proximal	2	no	15.689	20.892	EPSD	TCGA;ICGC;COSMIC	16.704	Gain
AGC_PKC_PKCa_PRKCA_ST	Q9UQ80	PA2G4	P17252	PRKCA	S361	Q367H	367	Missense	distal	6	no	17.625	17.670	EPSD	TCGA;ICGC;COSMIC	16.704	Up-regulation
AGC_PKC_PKCa_PRKCA_ST	Q9UQ80	PA2G4	P17252	PRKCA	S361	R364Q	364	Missense	distal	3	no	17.625	15.172	EPSD	TCGA;ICGC;COSMIC	16.704	Loss
AGC_PKC_PKCa_PRKCA_ST	Q9UQ80	PA2G4	P17252	PRKCA	S363	Q367H	367	Missense	distal	4	no	19.396	19.332	EPSD	TCGA;ICGC;COSMIC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	Q9UQ80	PA2G4	P17252	PRKCA	S363	R364Q	364	Missense	proximal	1	no	19.396	19.280	EPSD	TCGA;ICGC;COSMIC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	Q9UQ80	PA2G4	P17252	PRKCA	T366	Q367H	367	Missense	proximal	1	no	22.111	21.414	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	Q9UQ80	PA2G4	P17252	PRKCA	T366	R364Q	364	Missense	proximal	-2	no	22.111	20.352	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	Q9UQ80	PA2G4	P17252	PRKCA	T366	K372N	372	Missense	distal	6	no	22.111	21.949	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	P21359	NF1	P17252	PRKCA	S302	R304Q	304	Missense	proximal	2	no	18.764	14.930	EPSD	TCGA;ICGC;COSMIC	16.704	Loss
AGC_PKC_PKCa_PRKCA_ST	P21359	NF1	P17252	PRKCA	S858	S858Y	858	Missense	central	0	yes	16.837	0.000	EPSD	TCGA;ICGC;COSMIC	16.704	Loss
AGC_PKC_PKCa_PRKCA_ST	P21359	NF1	P17252	PRKCA	S858	S856N	856	Missense	proximal	-2	no	16.837	16.943	EPSD	TCGA;ICGC;COSMIC	16.704	Up-regulation
AGC_PKC_PKCa_PRKCA_ST	P21359	NF1	P17252	PRKCA	S858	T862I	862	Missense	distal	4	no	16.837	15.824	EPSD	TCGA;ICGC;COSMIC	16.704	Loss
AGC_PKC_PKCa_PRKCA_ST	P21359	NF1	P17252	PRKCA	S871	R873C	873	Missense	proximal	2	no	18.467	14.117	EPSD	TCGA;ICGC;COSMIC	16.704	Loss
AGC_PKC_PKCa_PRKCA_ST	P21359	NF1	P17252	PRKCA	S871	P866S	866	Missense	distal	-5	no	18.467	18.142	EPSD	TCGA;ICGC;COSMIC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	P21359	NF1	P17252	PRKCA	S876	R873C	873	Missense	distal	-3	no	18.150	15.411	EPSD	TCGA;ICGC;COSMIC	16.704	Loss
AGC_PKC_PKCa_PRKCA_ST	P21359	NF1	P17252	PRKCA	S1140	R1136W	1136	Missense	distal	-4	no	23.101	22.275	EPSD	TCGA;ICGC;COSMIC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	P21359	NF1	P17252	PRKCA	S1140	H1143Y	1143	Missense	distal	3	no	23.101	21.545	EPSD	TCGA	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	P21359	NF1	P17252	PRKCA	S1567	L1564F	1564	Missense	distal	-3	no	15.016	16.751	EPSD	TCGA;COSMIC	16.704	Gain
AGC_PKC_PKCa_PRKCA_ST	P21359	NF1	P17252	PRKCA	S1834	E1832K	1832	Missense	proximal	-2	no	14.906	17.405	EPSD	TCGA;COSMIC	16.704	Gain
AGC_PKC_PKCa_PRKCA_ST	P21359	NF1	P17252	PRKCA	S2181	D2184N	2184	Missense	distal	3	no	24.251	24.406	EPSD	TCGA;ICGC;COSMIC	16.704	Up-regulation
AGC_PKC_PKCa_PRKCA_ST	P21359	NF1	P17252	PRKCA	S2181	R2179L	2179	Missense	proximal	-2	no	24.251	21.563	EPSD	TCGA;ICGC;COSMIC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	P21359	NF1	P17252	PRKCA	S2181	S2188F	2188	Missense	distal	7	no	24.251	24.187	EPSD	TCGA;ICGC;COSMIC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	P21359	NF1	P17252	PRKCA	S2186	P2189R	2189	Missense	distal	3	no	17.618	19.149	EPSD	TCGA;COSMIC	16.704	Up-regulation
AGC_PKC_PKCa_PRKCA_ST	P21359	NF1	P17252	PRKCA	S2186	E2193K	2193	Missense	distal	7	no	17.618	17.764	EPSD	TCGA;ICGC;COSMIC	16.704	Up-regulation
AGC_PKC_PKCa_PRKCA_ST	P21359	NF1	P17252	PRKCA	S2186	D2184N	2184	Missense	proximal	-2	no	17.618	17.840	EPSD	TCGA;ICGC;COSMIC	16.704	Up-regulation
AGC_PKC_PKCa_PRKCA_ST	P21359	NF1	P17252	PRKCA	S2186	R2179L	2179	Missense	distal	-7	no	17.618	17.607	EPSD	TCGA;ICGC;COSMIC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	P21359	NF1	P17252	PRKCA	S2186	S2188F	2188	Missense	proximal	2	no	17.618	17.934	EPSD	TCGA;ICGC;COSMIC	16.704	Up-regulation
AGC_PKC_PKCa_PRKCA_ST	P21359	NF1	P17252	PRKCA	S2191	P2189R	2189	Missense	proximal	-2	no	15.051	18.093	EPSD	TCGA;COSMIC	16.704	Gain
AGC_PKC_PKCa_PRKCA_ST	P21359	NF1	P17252	PRKCA	S2191	E2193K	2193	Missense	proximal	2	no	15.051	20.330	EPSD	TCGA;ICGC;COSMIC	16.704	Gain
AGC_PKC_PKCa_PRKCA_ST	P21359	NF1	P17252	PRKCA	T2204	T2206R	2206	Missense	proximal	2	no	12.932	17.743	EPSD	TCGA;ICGC;COSMIC	16.704	Gain
AGC_PKC_PKCa_PRKCA_ST	P21359	NF1	P17252	PRKCA	S2460	L2463R	2463	Missense	distal	3	no	15.409	17.647	EPSD	TCGA;ICGC;COSMIC	16.704	Gain
AGC_PKC_PKCa_PRKCA_ST	P21359	NF1	P17252	PRKCA	T2487	D2482N	2482	Missense	distal	-5	no	17.104	17.134	EPSD	TCGA;COSMIC	16.704	Up-regulation
AGC_PKC_PKCa_PRKCA_ST	P21359	NF1	P17252	PRKCA	T2487	H2480R	2480	Missense	distal	-7	no	17.104	17.111	EPSD	TCGA;ICGC;COSMIC	16.704	Up-regulation
AGC_PKC_PKCa_PRKCA_ST	P21359	NF1	P17252	PRKCA	S2496	S2496F	2496	Missense	central	0	yes	18.867	0.000	EPSD	TCGA;COSMIC	16.704	Loss
AGC_PKC_PKCa_PRKCA_ST	P21359	NF1	P17252	PRKCA	S2515	R2517L	2517	Missense	proximal	2	no	19.017	14.030	EPSD	TCGA;ICGC;COSMIC	16.704	Loss
AGC_PKC_PKCa_PRKCA_ST	P21359	NF1	P17252	PRKCA	S2523	R2517L	2517	Missense	distal	-6	no	17.566	17.427	EPSD	TCGA;ICGC;COSMIC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	P21359	NF1	P17252	PRKCA	T2540	F2544V	2544	Missense	distal	4	no	17.266	16.306	EPSD	TCGA;COSMIC	16.704	Loss
AGC_PKC_PKCa_PRKCA_ST	P21359	NF1	P17252	PRKCA	S2597	K2595E	2595	Missense	proximal	-2	no	17.185	14.686	EPSD	TCGA;ICGC;COSMIC	16.704	Loss
AGC_PKC_PKCa_PRKCA_ST	P21359	NF1	P17252	PRKCA	S2597	L2604F	2604	Missense	distal	7	no	17.185	17.119	EPSD	TCGA;COSMIC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	P21359	NF1	P17252	PRKCA	S2597	S2599F	2599	Missense	proximal	2	no	17.185	17.502	EPSD	TCGA;ICGC;COSMIC	16.704	Up-regulation
AGC_PKC_PKCa_PRKCA_ST	P21359	NF1	P17252	PRKCA	S2597	L2604I	2604	Missense	distal	7	no	17.185	17.029	EPSD	TCGA	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	P21359	NF1	P17252	PRKCA	S2810	G2816R	2816	Missense	distal	6	no	20.229	20.378	EPSD	TCGA;COSMIC	16.704	Up-regulation
AGC_PKC_PKCa_PRKCA_ST	P21359	NF1	P17252	PRKCA	S2829	R2825T	2825	Missense	distal	-4	no	18.144	17.289	EPSD	TCGA;ICGC;COSMIC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	P21359	NF1	P17252	PRKCA	S2829	A2827P	2827	Missense	proximal	-2	no	18.144	18.187	EPSD	TCGA;ICGC;COSMIC	16.704	Up-regulation
AGC_PKC_PKCa_PRKCA_ST	P21359	NF1	P17252	PRKCA	S2829	Q2822H	2822	Missense	distal	-7	no	18.144	18.145	EPSD	TCGA;COSMIC	16.704	Up-regulation
AGC_PKC_PKCa_PRKCA_ST	P21359	NF1	P17252	PRKCA	S2834	A2827P	2827	Missense	distal	-7	no	21.932	21.927	EPSD	TCGA;ICGC;COSMIC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	P30086	PEBP1	P17252	PRKCA	S60	K62Q	62	Missense	proximal	2	no	17.037	13.624	EPSD	TCGA;ICGC;COSMIC	16.704	Loss
AGC_PKC_PKCa_PRKCA_ST	P30086	PEBP1	P17252	PRKCA	S60	L58V	58	Missense	proximal	-2	no	17.037	16.883	EPSD	TCGA;ICGC;COSMIC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	P30086	PEBP1	P17252	PRKCA	S60	G57V	57	Missense	distal	-3	no	17.037	16.609	EPSD	TCGA;ICGC;COSMIC	16.704	Loss
AGC_PKC_PKCa_PRKCA_ST	P30086	PEBP1	P17252	PRKCA	S60	S54L	54	Missense	distal	-6	no	17.037	16.971	EPSD	TCGA;ICGC;COSMIC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	P30086	PEBP1	P17252	PRKCA	S153	G147V	147	Missense	distal	-6	no	21.727	21.647	PhosphoSitePlus	TCGA;ICGC;COSMIC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	Q05193	DNM1	P17252	PRKCA	S264	S264P	264	Missense	central	0	yes	18.801	0.000	EPSD	TCGA;ICGC;COSMIC	16.704	Loss
AGC_PKC_PKCa_PRKCA_ST	Q05193	DNM1	P17252	PRKCA	S264	L260I	260	Missense	distal	-4	no	18.801	18.790	EPSD	TCGA;ICGC;COSMIC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	Q05193	DNM1	P17252	PRKCA	S264	R266H	266	Missense	proximal	2	no	18.801	13.777	EPSD	TCGA;ICGC;COSMIC;GDSC	16.704	Loss
AGC_PKC_PKCa_PRKCA_ST	Q05193	DNM1	P17252	PRKCA	S389	I392T	392	Missense	distal	3	no	16.376	17.089	EPSD	TCGA;ICGC;COSMIC	16.704	Gain
AGC_PKC_PKCa_PRKCA_ST	Q05193	DNM1	P17252	PRKCA	S619	A623D	623	Missense	distal	4	no	19.028	18.659	EPSD	TCGA;ICGC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	Q05193	DNM1	P17252	PRKCA	S619	Y626F	626	Missense	distal	7	no	19.028	18.970	EPSD	TCGA;ICGC;COSMIC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	Q05193	DNM1	P17252	PRKCA	S619	S619F	619	Missense	central	0	yes	19.028	0.000	EPSD	TCGA;ICGC;COSMIC	16.704	Loss
AGC_PKC_PKCa_PRKCA_ST	Q05193	DNM1	P17252	PRKCA	S774	P769L	769	Missense	distal	-5	no	18.929	18.902	EPSD	TCGA;ICGC;COSMIC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	Q05193	DNM1	P17252	PRKCA	S857	R854C	854	Missense	distal	-3	no	20.368	17.628	EPSD	TCGA	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	Q05193	DNM1	P17252	PRKCA	S857	R854H	854	Missense	distal	-3	no	20.368	16.511	EPSD	TCGA;ICGC	16.704	Loss
AGC_PKC_PKCa_PRKCA_ST	P04049	RAF1	P17252	PRKCA	S43	Q39E	39	Missense	distal	-4	no	19.600	19.281	EPSD;PhosphoSitePlus	TCGA;COSMIC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	P04049	RAF1	P17252	PRKCA	S43	R41W	41	Missense	proximal	-2	no	19.600	17.602	EPSD;PhosphoSitePlus	TCGA;COSMIC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	P04049	RAF1	P17252	PRKCA	T213	R215C	215	Missense	proximal	2	no	17.244	12.894	EPSD	TCGA;ICGC;COSMIC	16.704	Loss
AGC_PKC_PKCa_PRKCA_ST	P04049	RAF1	P17252	PRKCA	S220	R215C	215	Missense	distal	-5	no	19.272	18.597	EPSD	TCGA;ICGC;COSMIC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	P04049	RAF1	P17252	PRKCA	S220	R223M	223	Missense	distal	3	no	19.272	18.004	EPSD	TCGA;ICGC;COSMIC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	P04049	RAF1	P17252	PRKCA	S220	P225H	225	Missense	distal	5	no	19.272	18.995	EPSD	TCGA;ICGC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	P04049	RAF1	P17252	PRKCA	S252	S257L	257	Missense	distal	5	no	17.092	16.901	EPSD	TCGA;COSMIC;GDSC;CCLE	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	P04049	RAF1	P17252	PRKCA	S252	S257W	257	Missense	distal	5	no	17.092	16.726	EPSD	TCGA;COSMIC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	P04049	RAF1	P17252	PRKCA	S252	S259F	259	Missense	distal	7	no	17.092	17.029	EPSD	TCGA;COSMIC;GDSC;CCLE	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	P04049	RAF1	P17252	PRKCA	S257	S257L	257	Missense	central	0	yes	18.677	0.000	EPSD	TCGA;COSMIC;GDSC;CCLE	16.704	Loss
AGC_PKC_PKCa_PRKCA_ST	P04049	RAF1	P17252	PRKCA	S257	P261R	261	Missense	distal	4	no	18.677	19.123	EPSD	TCGA;COSMIC;CCLE	16.704	Up-regulation
AGC_PKC_PKCa_PRKCA_ST	P04049	RAF1	P17252	PRKCA	S257	S257W	257	Missense	central	0	yes	18.677	0.000	EPSD	TCGA;COSMIC	16.704	Loss
AGC_PKC_PKCa_PRKCA_ST	P04049	RAF1	P17252	PRKCA	S257	S259F	259	Missense	proximal	2	no	18.677	18.993	EPSD	TCGA;COSMIC;GDSC;CCLE	16.704	Up-regulation
AGC_PKC_PKCa_PRKCA_ST	P04049	RAF1	P17252	PRKCA	S257	H264Y	264	Missense	distal	7	no	18.677	18.696	EPSD	TCGA;COSMIC	16.704	Up-regulation
AGC_PKC_PKCa_PRKCA_ST	P04049	RAF1	P17252	PRKCA	S259	P261R	261	Missense	proximal	2	no	14.457	19.660	EPSD	TCGA;COSMIC;CCLE	16.704	Gain
AGC_PKC_PKCa_PRKCA_ST	P04049	RAF1	P17252	PRKCA	S338	S339I	339	Missense	proximal	1	no	16.463	18.125	EPSD	TCGA	16.704	Gain
AGC_PKC_PKCa_PRKCA_ST	P04049	RAF1	P17252	PRKCA	S352	R354W	354	Missense	proximal	2	no	16.787	11.347	EPSD	TCGA;COSMIC	16.704	Loss
AGC_PKC_PKCa_PRKCA_ST	P04049	RAF1	P17252	PRKCA	S352	T353I	353	Missense	proximal	1	no	16.787	18.123	EPSD	TCGA;COSMIC	16.704	Up-regulation
AGC_PKC_PKCa_PRKCA_ST	P04049	RAF1	P17252	PRKCA	S352	M350T	350	Missense	proximal	-2	no	16.787	15.875	EPSD	TCGA;COSMIC	16.704	Loss
AGC_PKC_PKCa_PRKCA_ST	P04049	RAF1	P17252	PRKCA	S499	E503K	503	Missense	distal	4	no	16.385	16.924	PhosphoSitePlus;EPSD	TCGA;COSMIC	16.704	Gain
AGC_PKC_PKCa_PRKCA_ST	P23975	SLC6A2	P17252	PRKCA	S203	G197S	197	Missense	distal	-6	no	16.698	16.732	EPSD	TCGA;ICGC;COSMIC	16.704	Gain
AGC_PKC_PKCa_PRKCA_ST	O94806	PRKD3	P17252	PRKCA	S9	S6P	6	Missense	distal	-3	no	18.875	17.896	EPSD	TCGA;ICGC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	O94806	PRKD3	P17252	PRKCA	S13	S6P	6	Missense	distal	-7	no	17.886	17.883	EPSD	TCGA;ICGC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	O94806	PRKD3	P17252	PRKCA	S31	P24S	24	Missense	distal	-7	no	18.670	18.673	EPSD	TCGA;ICGC;COSMIC	16.704	Up-regulation
AGC_PKC_PKCa_PRKCA_ST	O94806	PRKD3	P17252	PRKCA	S31	T34M	34	Missense	distal	3	no	18.670	19.239	EPSD	TCGA;ICGC;COSMIC	16.704	Up-regulation
AGC_PKC_PKCa_PRKCA_ST	O94806	PRKD3	P17252	PRKCA	S31	P28S	28	Missense	distal	-3	no	18.670	19.649	EPSD	TCGA;ICGC;COSMIC	16.704	Up-regulation
AGC_PKC_PKCa_PRKCA_ST	O94806	PRKD3	P17252	PRKCA	S31	P32L	32	Missense	proximal	1	no	18.670	19.097	EPSD	TCGA;ICGC;COSMIC	16.704	Up-regulation
AGC_PKC_PKCa_PRKCA_ST	O94806	PRKD3	P17252	PRKCA	S31	P32S	32	Missense	proximal	1	no	18.670	18.271	EPSD	TCGA;ICGC;COSMIC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	O94806	PRKD3	P17252	PRKCA	S37	S41P	41	Missense	distal	4	no	18.465	18.265	EPSD	TCGA;ICGC;COSMIC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	O94806	PRKD3	P17252	PRKCA	S37	T34M	34	Missense	distal	-3	no	18.465	19.656	EPSD	TCGA;ICGC;COSMIC	16.704	Up-regulation
AGC_PKC_PKCa_PRKCA_ST	O94806	PRKD3	P17252	PRKCA	S37	S41C	41	Missense	distal	4	no	18.465	17.310	EPSD	TCGA;ICGC;COSMIC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	O94806	PRKD3	P17252	PRKCA	S37	G43E	43	Missense	distal	6	no	18.465	18.508	EPSD	TCGA;ICGC;COSMIC	16.704	Up-regulation
AGC_PKC_PKCa_PRKCA_ST	O94806	PRKD3	P17252	PRKCA	S37	P32L	32	Missense	distal	-5	no	18.465	18.438	EPSD	TCGA;ICGC;COSMIC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	O94806	PRKD3	P17252	PRKCA	S37	P32S	32	Missense	distal	-5	no	18.465	18.139	EPSD	TCGA;ICGC;COSMIC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	O94806	PRKD3	P17252	PRKCA	S213	K209N	209	Missense	distal	-4	no	20.336	19.778	EPSD	TCGA;ICGC;COSMIC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	O94806	PRKD3	P17252	PRKCA	S247	H241Y	241	Missense	distal	-6	no	17.954	17.895	EPSD	TCGA;ICGC;COSMIC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	O94806	PRKD3	P17252	PRKCA	S252	R256H	256	Missense	distal	4	no	19.862	19.580	EPSD	TCGA;ICGC;COSMIC;GDSC;CCLE	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	O94806	PRKD3	P17252	PRKCA	S315	P318S	318	Missense	distal	3	no	20.306	20.446	EPSD	TCGA;ICGC	16.704	Up-regulation
AGC_PKC_PKCa_PRKCA_ST	O94806	PRKD3	P17252	PRKCA	S315	R312H	312	Missense	distal	-3	no	20.306	16.450	EPSD	TCGA;ICGC;COSMIC	16.704	Loss
AGC_PKC_PKCa_PRKCA_ST	O94806	PRKD3	P17252	PRKCA	S406	M401I	401	Missense	distal	-5	no	21.892	21.487	EPSD	TCGA;ICGC;COSMIC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	O94806	PRKD3	P17252	PRKCA	S406	L400Q	400	Missense	distal	-6	no	21.892	21.887	EPSD	TCGA;ICGC;COSMIC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	O94806	PRKD3	P17252	PRKCA	S415	W422L	422	Missense	distal	7	no	18.899	19.036	EPSD	TCGA;ICGC;COSMIC	16.704	Up-regulation
AGC_PKC_PKCa_PRKCA_ST	O94806	PRKD3	P17252	PRKCA	S470	R467G	467	Missense	distal	-3	no	19.758	16.496	EPSD	TCGA;ICGC;COSMIC	16.704	Loss
AGC_PKC_PKCa_PRKCA_ST	O94806	PRKD3	P17252	PRKCA	S735	A741T	741	Missense	distal	6	no	20.009	19.931	EPSD	TCGA;ICGC;COSMIC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	O94806	PRKD3	P17252	PRKCA	S822	L827F	827	Missense	distal	5	no	20.749	20.973	EPSD	TCGA;ICGC;COSMIC	16.704	Up-regulation
AGC_PKC_PKCa_PRKCA_ST	O94806	PRKD3	P17252	PRKCA	S822	R820C	820	Missense	proximal	-2	no	20.749	19.049	EPSD	TCGA;ICGC;COSMIC;CCLE	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	P10275	AR	P17252	PRKCA	S16	R13G	13	Missense	distal	-3	no	18.915	15.654	EPSD	TCGA;ICGC;COSMIC	16.704	Loss
AGC_PKC_PKCa_PRKCA_ST	P10275	AR	P17252	PRKCA	S16	P15L	15	Missense	proximal	-1	no	18.915	18.796	EPSD	TCGA;ICGC;COSMIC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	P10275	AR	P17252	PRKCA	S16	Y19C	19	Missense	distal	3	no	18.915	18.565	EPSD	TCGA;ICGC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	P10275	AR	P17252	PRKCA	S16	K17N	17	Missense	proximal	1	no	18.915	17.751	EPSD	TCGA;ICGC;COSMIC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	P10275	AR	P17252	PRKCA	T18	R13G	13	Missense	distal	-5	no	19.880	19.590	EPSD	TCGA;ICGC;COSMIC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	P10275	AR	P17252	PRKCA	T18	P15L	15	Missense	distal	-3	no	19.880	19.373	EPSD	TCGA;ICGC;COSMIC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	P10275	AR	P17252	PRKCA	T18	Y19C	19	Missense	proximal	1	no	19.880	17.407	EPSD	TCGA;ICGC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	P10275	AR	P17252	PRKCA	T18	K17N	17	Missense	proximal	-1	no	19.880	19.278	EPSD	TCGA;ICGC;COSMIC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	P10275	AR	P17252	PRKCA	S29	E32K	32	Missense	distal	3	no	16.872	17.488	EPSD	TCGA;ICGC;COSMIC;GDSC;CCLE	16.704	Up-regulation
AGC_PKC_PKCa_PRKCA_ST	P10275	AR	P17252	PRKCA	S29	R31C	31	Missense	proximal	2	no	16.872	12.522	EPSD	TCGA;ICGC;COSMIC	16.704	Loss
AGC_PKC_PKCa_PRKCA_ST	P10275	AR	P17252	PRKCA	S29	R31H	31	Missense	proximal	2	no	16.872	11.848	EPSD	TCGA;ICGC;COSMIC	16.704	Loss
AGC_PKC_PKCa_PRKCA_ST	P10275	AR	P17252	PRKCA	S29	L26M	26	Missense	distal	-3	no	16.872	18.255	EPSD	TCGA;ICGC;COSMIC	16.704	Up-regulation
AGC_PKC_PKCa_PRKCA_ST	P10275	AR	P17252	PRKCA	S29	Q28H	28	Missense	proximal	-1	no	16.872	17.366	EPSD	TCGA;ICGC;COSMIC	16.704	Up-regulation
AGC_PKC_PKCa_PRKCA_ST	P10275	AR	P17252	PRKCA	S208	A211T	211	Missense	distal	3	no	18.352	18.113	EPSD	TCGA;ICGC;COSMIC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	P10275	AR	P17252	PRKCA	S208	A211V	211	Missense	distal	3	no	18.352	18.096	EPSD	TCGA;ICGC;COSMIC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	P10275	AR	P17252	PRKCA	S579	F583I	583	Missense	distal	4	no	17.121	16.038	PhosphoSitePlus	TCGA;ICGC;COSMIC	16.704	Loss
AGC_PKC_PKCa_PRKCA_ST	P10275	AR	P17252	PRKCA	S579	G578R	578	Missense	proximal	-1	no	17.121	17.260	PhosphoSitePlus	TCGA;ICGC;COSMIC	16.704	Up-regulation
AGC_PKC_PKCa_PRKCA_ST	P10415	BCL2	P17252	PRKCA	S24	K17M	17	Missense	distal	-7	no	20.144	20.146	EPSD	TCGA;ICGC;COSMIC	16.704	Up-regulation
AGC_PKC_PKCa_PRKCA_ST	P10415	BCL2	P17252	PRKCA	S24	Y28H	28	Missense	distal	4	no	20.144	20.505	EPSD	TCGA;ICGC;COSMIC	16.704	Up-regulation
AGC_PKC_PKCa_PRKCA_ST	P10415	BCL2	P17252	PRKCA	S24	D31N	31	Missense	distal	7	no	20.144	20.117	EPSD	TCGA;ICGC;COSMIC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	P00749	PLAU	P17252	PRKCA	S341	R343W	343	Missense	proximal	2	no	18.203	12.763	EPSD	TCGA;COSMIC	16.704	Loss
AGC_PKC_PKCa_PRKCA_ST	P00749	PLAU	P17252	PRKCA	S341	M334I	334	Missense	distal	-7	no	18.203	18.191	EPSD	TCGA;COSMIC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	P01589	IL2RA	P17252	PRKCA	S268	R269T	269	Missense	proximal	1	no	19.951	19.104	PhosphoSitePlus;EPSD	TCGA;COSMIC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	P01589	IL2RA	P17252	PRKCA	S268	W261C	261	Missense	distal	-7	no	19.951	19.948	PhosphoSitePlus;EPSD	TCGA;COSMIC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	P13569	CFTR	P17252	PRKCA	S4	K8N	8	Missense	distal	4	no	17.326	16.199	EPSD	TCGA;ICGC;COSMIC	16.704	Loss
AGC_PKC_PKCa_PRKCA_ST	P13569	CFTR	P17252	PRKCA	T501	K503R	503	Missense	proximal	2	no	18.338	18.759	EPSD	TCGA;COSMIC	16.704	Up-regulation
AGC_PKC_PKCa_PRKCA_ST	P13569	CFTR	P17252	PRKCA	T501	S495F	495	Missense	distal	-6	no	18.338	18.253	EPSD	TCGA;ICGC;COSMIC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	P13569	CFTR	P17252	PRKCA	T501	N505D	505	Missense	distal	4	no	18.338	18.695	EPSD	TCGA;ICGC;COSMIC	16.704	Up-regulation
AGC_PKC_PKCa_PRKCA_ST	P13569	CFTR	P17252	PRKCA	S641	L644P	644	Missense	distal	3	no	17.253	17.960	EPSD	TCGA;COSMIC	16.704	Up-regulation
AGC_PKC_PKCa_PRKCA_ST	P13569	CFTR	P17252	PRKCA	S641	P638S	638	Missense	distal	-3	no	17.253	18.232	EPSD	TCGA;COSMIC	16.704	Up-regulation
AGC_PKC_PKCa_PRKCA_ST	P13569	CFTR	P17252	PRKCA	S660	F653Y	653	Missense	distal	-7	no	19.706	19.714	EPSD;PhosphoSitePlus	TCGA;COSMIC	16.704	Up-regulation
AGC_PKC_PKCa_PRKCA_ST	P13569	CFTR	P17252	PRKCA	S686	E681D	681	Missense	distal	-5	no	19.152	19.074	EPSD	TCGA;ICGC;COSMIC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	P13569	CFTR	P17252	PRKCA	S700	S707Y	707	Missense	distal	7	no	18.593	18.587	EPSD	TCGA	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	P13569	CFTR	P17252	PRKCA	S707	S712F	712	Missense	distal	5	no	19.036	19.070	EPSD	TCGA;COSMIC	16.704	Up-regulation
AGC_PKC_PKCa_PRKCA_ST	P13569	CFTR	P17252	PRKCA	S707	R709Q	709	Missense	proximal	2	no	19.036	15.202	EPSD	TCGA;COSMIC	16.704	Loss
AGC_PKC_PKCa_PRKCA_ST	P13569	CFTR	P17252	PRKCA	S707	S707Y	707	Missense	central	0	yes	19.036	0.000	EPSD	TCGA	16.704	Loss
AGC_PKC_PKCa_PRKCA_ST	P13569	CFTR	P17252	PRKCA	S737	Q744L	744	Missense	distal	7	no	20.116	20.077	PhosphoSitePlus;EPSD	TCGA;COSMIC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	P13569	CFTR	P17252	PRKCA	S737	D741N	741	Missense	distal	4	no	20.116	19.759	PhosphoSitePlus;EPSD	TCGA;COSMIC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	P13569	CFTR	P17252	PRKCA	S768	T774I	774	Missense	distal	6	no	19.597	19.611	EPSD	TCGA;COSMIC	16.704	Up-regulation
AGC_PKC_PKCa_PRKCA_ST	P13569	CFTR	P17252	PRKCA	S768	R765S	765	Missense	distal	-3	no	19.597	16.727	EPSD	TCGA;COSMIC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	P13569	CFTR	P17252	PRKCA	S768	R764Q	764	Missense	distal	-4	no	19.597	19.220	EPSD	TCGA;COSMIC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	P13569	CFTR	P17252	PRKCA	S790	A789S	789	Missense	proximal	-1	no	18.923	19.482	EPSD	TCGA;COSMIC	16.704	Up-regulation
AGC_PKC_PKCa_PRKCA_ST	P13569	CFTR	P17252	PRKCA	S1248	G1247A	1247	Missense	proximal	-1	no	21.308	20.501	EPSD	TCGA;COSMIC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	P13569	CFTR	P17252	PRKCA	S1248	S1255L	1255	Missense	distal	7	no	21.308	21.311	EPSD	TCGA;COSMIC	16.704	Up-regulation
AGC_PKC_PKCa_PRKCA_ST	P13569	CFTR	P17252	PRKCA	S1248	L1253S	1253	Missense	distal	5	no	21.308	21.499	EPSD	TCGA;COSMIC	16.704	Up-regulation
AGC_PKC_PKCa_PRKCA_ST	P13569	CFTR	P17252	PRKCA	S1426	D1425N	1425	Missense	proximal	-1	no	16.529	16.867	EPSD	TCGA;COSMIC	16.704	Gain
AGC_PKC_PKCa_PRKCA_ST	P13569	CFTR	P17252	PRKCA	S1426	V1421E	1421	Missense	distal	-5	no	16.529	16.786	EPSD	TCGA;COSMIC	16.704	Gain
AGC_PKC_PKCa_PRKCA_ST	P13569	CFTR	P17252	PRKCA	S1444	S1442R	1442	Missense	proximal	-2	no	15.595	18.897	EPSD	TCGA;COSMIC	16.704	Gain
AGC_PKC_PKCa_PRKCA_ST	P13569	CFTR	P17252	PRKCA	S1455	S1456I	1456	Missense	proximal	1	no	17.317	18.979	EPSD	TCGA;COSMIC	16.704	Up-regulation
AGC_PKC_PKCa_PRKCA_ST	P13569	CFTR	P17252	PRKCA	S1455	S1460F	1460	Missense	distal	5	no	17.317	17.351	EPSD	TCGA;COSMIC	16.704	Up-regulation
AGC_PKC_PKCa_PRKCA_ST	P13569	CFTR	P17252	PRKCA	S1455	P1451S	1451	Missense	distal	-4	no	17.317	17.488	EPSD	TCGA;COSMIC	16.704	Up-regulation
AGC_PKC_PKCa_PRKCA_ST	P13569	CFTR	P17252	PRKCA	S1455	F1450V	1450	Missense	distal	-5	no	17.317	17.077	EPSD	TCGA;COSMIC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	P13569	CFTR	P17252	PRKCA	S1456	S1456I	1456	Missense	central	0	yes	17.642	0.000	EPSD	TCGA;COSMIC	16.704	Loss
AGC_PKC_PKCa_PRKCA_ST	P13569	CFTR	P17252	PRKCA	S1456	S1460F	1460	Missense	distal	4	no	17.642	17.281	EPSD	TCGA;COSMIC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	P13569	CFTR	P17252	PRKCA	S1456	P1451S	1451	Missense	distal	-5	no	17.642	17.317	EPSD	TCGA;COSMIC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	P13569	CFTR	P17252	PRKCA	S1456	F1450V	1450	Missense	distal	-6	no	17.642	17.614	EPSD	TCGA;COSMIC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	Q15172	PPP2R5A	P17252	PRKCA	S28	R30C	30	Missense	proximal	2	no	24.450	20.100	EPSD	TCGA;ICGC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	Q15172	PPP2R5A	P17252	PRKCA	T281	M279V	279	Missense	proximal	-2	no	17.530	16.670	EPSD	TCGA	16.704	Loss
AGC_PKC_PKCa_PRKCA_ST	Q9Y624	F11R	P17252	PRKCA	S274	K271Q	271	Missense	distal	-3	no	18.112	17.280	EPSD	TCGA;ICGC;COSMIC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	Q9Y624	F11R	P17252	PRKCA	S274	K277N	277	Missense	distal	3	no	18.112	17.164	EPSD	TCGA;ICGC;COSMIC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	Q9Y624	F11R	P17252	PRKCA	S284	K277N	277	Missense	distal	-7	no	18.239	18.234	PhosphoSitePlus	TCGA;ICGC;COSMIC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	Q9Y624	F11R	P17252	PRKCA	S284	R286Q	286	Missense	proximal	2	no	18.239	14.405	PhosphoSitePlus	TCGA;ICGC;COSMIC;GDSC;CCLE	16.704	Loss
AGC_PKC_PKCa_PRKCA_ST	Q9UBS0	RPS6KB2	P17252	PRKCA	S219	C216Y	216	Missense	distal	-3	no	17.293	15.472	EPSD	TCGA;ICGC;COSMIC	16.704	Loss
AGC_PKC_PKCa_PRKCA_ST	Q9UBS0	RPS6KB2	P17252	PRKCA	S410	S410L	410	Missense	central	0	yes	21.803	0.000	EPSD	TCGA;ICGC;COSMIC	16.704	Loss
AGC_PKC_PKCa_PRKCA_ST	Q9UBS0	RPS6KB2	P17252	PRKCA	S416	R419W	419	Missense	distal	3	no	20.048	17.114	EPSD	TCGA;ICGC;COSMIC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	Q9UBS0	RPS6KB2	P17252	PRKCA	S416	S410L	410	Missense	distal	-6	no	20.048	19.983	EPSD	TCGA;ICGC;COSMIC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	Q9UBS0	RPS6KB2	P17252	PRKCA	S417	R419W	419	Missense	proximal	2	no	18.341	12.901	EPSD	TCGA;ICGC;COSMIC	16.704	Loss
AGC_PKC_PKCa_PRKCA_ST	Q9UBS0	RPS6KB2	P17252	PRKCA	S417	S410L	410	Missense	distal	-7	no	18.341	18.336	EPSD	TCGA;ICGC;COSMIC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	P29972	AQP1	P17252	PRKCA	S236	P233S	233	Missense	distal	-3	no	15.858	16.837	EPSD	TCGA;COSMIC	16.704	Gain
AGC_PKC_PKCa_PRKCA_ST	Q05209	PTPN12	P17252	PRKCA	S39	T44A	44	Missense	distal	5	no	23.213	23.491	PhosphoSitePlus;EPSD	TCGA;ICGC;COSMIC	16.704	Up-regulation
AGC_PKC_PKCa_PRKCA_ST	Q05209	PTPN12	P17252	PRKCA	S39	K46M	46	Missense	distal	7	no	23.213	23.127	PhosphoSitePlus;EPSD	TCGA;COSMIC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	Q05209	PTPN12	P17252	PRKCA	S39	R34W	34	Missense	distal	-5	no	23.213	22.899	PhosphoSitePlus;EPSD	TCGA;COSMIC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	Q05209	PTPN12	P17252	PRKCA	T40	T44A	44	Missense	distal	4	no	17.374	17.821	EPSD	TCGA;ICGC;COSMIC	16.704	Up-regulation
AGC_PKC_PKCa_PRKCA_ST	Q05209	PTPN12	P17252	PRKCA	T40	K46M	46	Missense	distal	6	no	17.374	17.314	EPSD	TCGA;COSMIC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	Q05209	PTPN12	P17252	PRKCA	T40	R34W	34	Missense	distal	-6	no	17.374	17.090	EPSD	TCGA;COSMIC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	Q05209	PTPN12	P17252	PRKCA	S186	R187C	187	Missense	proximal	1	no	17.667	14.832	EPSD	TCGA;COSMIC	16.704	Loss
AGC_PKC_PKCa_PRKCA_ST	Q05209	PTPN12	P17252	PRKCA	S421	E424K	424	Missense	distal	3	no	16.471	17.087	EPSD	TCGA;COSMIC	16.704	Gain
AGC_PKC_PKCa_PRKCA_ST	Q05209	PTPN12	P17252	PRKCA	S435	K428T	428	Missense	distal	-7	no	17.671	17.668	EPSD;PhosphoSitePlus	TCGA;COSMIC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	Q05209	PTPN12	P17252	PRKCA	S435	R432Q	432	Missense	distal	-3	no	17.671	14.813	EPSD;PhosphoSitePlus	TCGA;COSMIC;GDSC;CCLE	16.704	Loss
AGC_PKC_PKCa_PRKCA_ST	P21399	ACO1	P17252	PRKCA	S138	K141N	141	Missense	distal	3	no	20.036	19.089	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	P21399	ACO1	P17252	PRKCA	S533	N537K	537	Missense	distal	4	no	15.737	16.864	EPSD	TCGA;ICGC;COSMIC	16.704	Gain
AGC_PKC_PKCa_PRKCA_ST	P21399	ACO1	P17252	PRKCA	T702	E705Q	705	Missense	distal	3	no	20.388	19.173	EPSD	TCGA;ICGC;COSMIC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	P21399	ACO1	P17252	PRKCA	T702	N707K	707	Missense	distal	5	no	20.388	20.894	EPSD	TCGA;ICGC;COSMIC	16.704	Up-regulation
AGC_PKC_PKCa_PRKCA_ST	P21399	ACO1	P17252	PRKCA	S711	E705Q	705	Missense	distal	-6	no	19.899	19.830	PhosphoSitePlus;EPSD	TCGA;ICGC;COSMIC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	P21399	ACO1	P17252	PRKCA	S711	R712H	712	Missense	proximal	1	no	19.899	19.085	PhosphoSitePlus;EPSD	TCGA;ICGC;COSMIC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	P21399	ACO1	P17252	PRKCA	S711	N707K	707	Missense	distal	-4	no	19.899	20.457	PhosphoSitePlus;EPSD	TCGA;ICGC;COSMIC	16.704	Up-regulation
AGC_PKC_PKCa_PRKCA_ST	P21399	ACO1	P17252	PRKCA	S711	A717T	717	Missense	distal	6	no	19.899	19.821	PhosphoSitePlus;EPSD	TCGA;ICGC;COSMIC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	P21399	ACO1	P17252	PRKCA	S711	R712C	712	Missense	proximal	1	no	19.899	17.063	PhosphoSitePlus;EPSD	TCGA;ICGC;COSMIC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	P21731	TBXA2R	P17252	PRKCA	S128	G133D	133	Missense	distal	5	no	17.295	17.214	EPSD	TCGA;COSMIC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	P21731	TBXA2R	P17252	PRKCA	S128	A125T	125	Missense	distal	-3	no	17.295	17.580	EPSD	TCGA;ICGC;COSMIC	16.704	Up-regulation
AGC_PKC_PKCa_PRKCA_ST	P21731	TBXA2R	P17252	PRKCA	S145	A149T	149	Missense	distal	4	no	18.398	17.950	PhosphoSitePlus;EPSD	TCGA;ICGC;COSMIC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	P21731	TBXA2R	P17252	PRKCA	S324	R318H	318	Missense	distal	-6	no	18.282	18.214	EPSD;PhosphoSitePlus	TCGA	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	P21731	TBXA2R	P17252	PRKCA	S324	R326Q	326	Missense	proximal	2	no	18.282	14.448	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	16.704	Loss
AGC_PKC_PKCa_PRKCA_ST	P06213	INSR	P17252	PRKCA	S407	S400C	400	Missense	distal	-7	no	17.583	17.569	EPSD	TCGA;ICGC;COSMIC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	P06213	INSR	P17252	PRKCA	S407	Y401F	401	Missense	distal	-6	no	17.583	17.551	EPSD	TCGA;ICGC;COSMIC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	P06213	INSR	P17252	PRKCA	S407	A402T	402	Missense	distal	-5	no	17.583	17.964	EPSD	TCGA;ICGC;COSMIC;GDSC;CCLE	16.704	Up-regulation
AGC_PKC_PKCa_PRKCA_ST	P06213	INSR	P17252	PRKCA	S407	S407F	407	Missense	central	0	yes	17.583	0.000	EPSD	TCGA;ICGC;COSMIC	16.704	Loss
AGC_PKC_PKCa_PRKCA_ST	P06213	INSR	P17252	PRKCA	S841	Y839C	839	Missense	proximal	-2	no	17.781	18.809	EPSD	TCGA;COSMIC	16.704	Up-regulation
AGC_PKC_PKCa_PRKCA_ST	P06213	INSR	P17252	PRKCA	S922	P918L	918	Missense	distal	-4	no	17.993	17.733	EPSD	TCGA;COSMIC;GDSC;CCLE	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	P06213	INSR	P17252	PRKCA	S922	V923M	923	Missense	proximal	1	no	17.993	17.653	EPSD	TCGA;COSMIC;GDSC;CCLE	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	P06213	INSR	P17252	PRKCA	S922	R924Q	924	Missense	proximal	2	no	17.993	14.159	EPSD	TCGA	16.704	Loss
AGC_PKC_PKCa_PRKCA_ST	P06213	INSR	P17252	PRKCA	S929	N933Y	933	Missense	distal	4	no	16.446	16.758	EPSD	TCGA;COSMIC	16.704	Gain
AGC_PKC_PKCa_PRKCA_ST	P06213	INSR	P17252	PRKCA	S1064	R1066L	1066	Missense	proximal	2	no	17.717	12.730	PhosphoSitePlus;EPSD	TCGA;COSMIC	16.704	Loss
AGC_PKC_PKCa_PRKCA_ST	P06213	INSR	P17252	PRKCA	S1064	R1068W	1068	Missense	distal	4	no	17.717	16.181	PhosphoSitePlus;EPSD	TCGA;COSMIC	16.704	Loss
AGC_PKC_PKCa_PRKCA_ST	P06213	INSR	P17252	PRKCA	S1064	S1062P	1062	Missense	proximal	-2	no	17.717	17.977	PhosphoSitePlus;EPSD	TCGA	16.704	Up-regulation
AGC_PKC_PKCa_PRKCA_ST	P06213	INSR	P17252	PRKCA	S1354	E1356K	1356	Missense	proximal	2	no	14.372	19.652	EPSD	TCGA;COSMIC	16.704	Gain
AGC_PKC_PKCa_PRKCA_ST	Q02156	PRKCE	P17252	PRKCA	S24	H27Y	27	Missense	distal	3	no	18.000	16.444	EPSD	TCGA;ICGC;COSMIC	16.704	Loss
AGC_PKC_PKCa_PRKCA_ST	Q02156	PRKCE	P17252	PRKCA	S24	S17N	17	Missense	distal	-7	no	18.000	17.995	EPSD	TCGA;ICGC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	Q02156	PRKCE	P17252	PRKCA	S234	V232L	232	Missense	proximal	-2	no	19.631	19.785	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	16.704	Up-regulation
AGC_PKC_PKCa_PRKCA_ST	Q02156	PRKCE	P17252	PRKCA	S234	R236G	236	Missense	proximal	2	no	19.631	14.386	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	16.704	Loss
AGC_PKC_PKCa_PRKCA_ST	Q02156	PRKCE	P17252	PRKCA	S339	E341K	341	Missense	proximal	2	no	12.709	17.988	EPSD	TCGA;ICGC;COSMIC	16.704	Gain
AGC_PKC_PKCa_PRKCA_ST	Q02156	PRKCE	P17252	PRKCA	S368	E374K	374	Missense	distal	6	no	17.236	17.330	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	16.704	Up-regulation
AGC_PKC_PKCa_PRKCA_ST	Q02156	PRKCE	P17252	PRKCA	S368	R364W	364	Missense	distal	-4	no	17.236	16.409	EPSD;PhosphoSitePlus	TCGA;ICGC	16.704	Loss
AGC_PKC_PKCa_PRKCA_ST	Q96PY5	FMNL2	P17252	PRKCA	S9	A16P	16	Missense	distal	7	no	19.474	19.512	EPSD	TCGA;ICGC;COSMIC	16.704	Up-regulation
AGC_PKC_PKCa_PRKCA_ST	Q96PY5	FMNL2	P17252	PRKCA	S9	A16V	16	Missense	distal	7	no	19.474	19.420	EPSD	TCGA;ICGC;COSMIC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	Q96PY5	FMNL2	P17252	PRKCA	T92	P89S	89	Missense	distal	-3	no	16.363	17.341	EPSD	TCGA;ICGC;COSMIC	16.704	Gain
AGC_PKC_PKCa_PRKCA_ST	Q96PY5	FMNL2	P17252	PRKCA	S205	R207I	207	Missense	proximal	2	no	17.694	12.662	EPSD	TCGA;ICGC;COSMIC	16.704	Loss
AGC_PKC_PKCa_PRKCA_ST	Q96PY5	FMNL2	P17252	PRKCA	T450	V448A	448	Missense	proximal	-2	no	16.916	16.672	EPSD	TCGA;ICGC;COSMIC	16.704	Loss
AGC_PKC_PKCa_PRKCA_ST	Q96PY5	FMNL2	P17252	PRKCA	S466	I472S	472	Missense	distal	6	no	18.167	18.202	EPSD	TCGA;ICGC;COSMIC	16.704	Up-regulation
AGC_PKC_PKCa_PRKCA_ST	Q96PY5	FMNL2	P17252	PRKCA	S466	Q463E	463	Missense	distal	-3	no	18.167	16.087	EPSD	TCGA;ICGC;COSMIC	16.704	Loss
AGC_PKC_PKCa_PRKCA_ST	Q96PY5	FMNL2	P17252	PRKCA	S466	E460K	460	Missense	distal	-6	no	18.167	18.235	EPSD	TCGA;ICGC;COSMIC	16.704	Up-regulation
AGC_PKC_PKCa_PRKCA_ST	Q96PY5	FMNL2	P17252	PRKCA	S466	E469K	469	Missense	distal	3	no	18.167	18.783	EPSD	TCGA;ICGC;COSMIC	16.704	Up-regulation
AGC_PKC_PKCa_PRKCA_ST	Q96PY5	FMNL2	P17252	PRKCA	T467	E469K	469	Missense	proximal	2	no	15.993	21.272	EPSD	TCGA;ICGC;COSMIC	16.704	Gain
AGC_PKC_PKCa_PRKCA_ST	Q96PY5	FMNL2	P17252	PRKCA	S522	G524R	524	Missense	proximal	2	no	12.073	17.318	EPSD	TCGA;ICGC;COSMIC	16.704	Gain
AGC_PKC_PKCa_PRKCA_ST	Q96PY5	FMNL2	P17252	PRKCA	S834	M832I	832	Missense	proximal	-2	no	19.601	17.995	EPSD	TCGA;COSMIC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	Q96PY5	FMNL2	P17252	PRKCA	S834	S834N	834	Missense	central	0	yes	19.601	0.000	EPSD	TCGA;COSMIC	16.704	Loss
AGC_PKC_PKCa_PRKCA_ST	Q96PY5	FMNL2	P17252	PRKCA	S834	V840I	840	Missense	distal	6	no	19.601	19.656	EPSD	TCGA;COSMIC	16.704	Up-regulation
AGC_PKC_PKCa_PRKCA_ST	Q96PY5	FMNL2	P17252	PRKCA	S835	G842R	842	Missense	distal	7	no	19.529	19.554	EPSD	TCGA;COSMIC	16.704	Up-regulation
AGC_PKC_PKCa_PRKCA_ST	Q96PY5	FMNL2	P17252	PRKCA	S835	M832I	832	Missense	distal	-3	no	19.529	18.014	EPSD	TCGA;COSMIC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	Q96PY5	FMNL2	P17252	PRKCA	S835	S834N	834	Missense	proximal	-1	no	19.529	19.372	EPSD	TCGA;COSMIC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	Q96PY5	FMNL2	P17252	PRKCA	S835	V840I	840	Missense	distal	5	no	19.529	19.617	EPSD	TCGA;COSMIC	16.704	Up-regulation
AGC_PKC_PKCa_PRKCA_ST	Q96PY5	FMNL2	P17252	PRKCA	S1018	S1018F	1018	Missense	central	0	yes	18.690	0.000	EPSD	TCGA;COSMIC	16.704	Loss
AGC_PKC_PKCa_PRKCA_ST	Q05940	SLC18A2	P17252	PRKCA	S15	R10H	10	Missense	distal	-5	no	21.540	21.184	EPSD;PhosphoSitePlus	TCGA;ICGC;CCLE	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	Q05940	SLC18A2	P17252	PRKCA	S15	R10C	10	Missense	distal	-5	no	21.540	20.864	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	Q05940	SLC18A2	P17252	PRKCA	S50	K55N	55	Missense	distal	5	no	18.249	17.743	EPSD	TCGA;ICGC;COSMIC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	Q05940	SLC18A2	P17252	PRKCA	S50	E54Q	54	Missense	distal	4	no	18.249	18.400	EPSD	TCGA;ICGC;COSMIC	16.704	Up-regulation
AGC_PKC_PKCa_PRKCA_ST	Q05940	SLC18A2	P17252	PRKCA	S50	P45S	45	Missense	distal	-5	no	18.249	17.924	EPSD	TCGA;ICGC;COSMIC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	Q05940	SLC18A2	P17252	PRKCA	S50	K52T	52	Missense	proximal	2	no	18.249	13.860	EPSD	TCGA;ICGC;COSMIC	16.704	Loss
AGC_PKC_PKCa_PRKCA_ST	Q05940	SLC18A2	P17252	PRKCA	S50	I51V	51	Missense	proximal	1	no	18.249	17.538	EPSD	TCGA;ICGC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	Q05940	SLC18A2	P17252	PRKCA	S279	G282R	282	Missense	distal	3	no	21.202	21.842	EPSD	TCGA;ICGC;COSMIC	16.704	Up-regulation
AGC_PKC_PKCa_PRKCA_ST	Q05940	SLC18A2	P17252	PRKCA	S279	R274L	274	Missense	distal	-5	no	21.202	21.075	EPSD	TCGA;ICGC;COSMIC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	P35612	ADD2	P17252	PRKCA	T5	E3K	3	Missense	proximal	-2	no	14.710	17.209	EPSD	TCGA;ICGC;COSMIC;GDSC;CCLE	16.704	Gain
AGC_PKC_PKCa_PRKCA_ST	P35612	ADD2	P17252	PRKCA	S62	E65K	65	Missense	distal	3	no	18.890	19.506	EPSD	TCGA;ICGC;COSMIC	16.704	Up-regulation
AGC_PKC_PKCa_PRKCA_ST	P35612	ADD2	P17252	PRKCA	S62	M56I	56	Missense	distal	-6	no	18.890	18.796	EPSD	TCGA;ICGC;COSMIC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	P35612	ADD2	P17252	PRKCA	T631	A634V	634	Missense	distal	3	no	17.661	17.404	EPSD	TCGA;ICGC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	P35612	ADD2	P17252	PRKCA	T631	E630K	630	Missense	proximal	-1	no	17.661	18.087	EPSD	TCGA;ICGC;COSMIC	16.704	Up-regulation
AGC_PKC_PKCa_PRKCA_ST	P35612	ADD2	P17252	PRKCA	T631	K628N	628	Missense	distal	-3	no	17.661	15.460	EPSD	TCGA;ICGC	16.704	Loss
AGC_PKC_PKCa_PRKCA_ST	P35612	ADD2	P17252	PRKCA	S686	G690S	690	Missense	distal	4	no	16.369	16.726	EPSD	TCGA;ICGC;COSMIC	16.704	Gain
AGC_PKC_PKCa_PRKCA_ST	P35612	ADD2	P17252	PRKCA	S703	K707N	707	Missense	distal	4	no	18.466	17.339	EPSD	TCGA;ICGC;COSMIC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	P35612	ADD2	P17252	PRKCA	S713	K707N	707	Missense	distal	-6	no	18.575	18.451	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	P35612	ADD2	P17252	PRKCA	S713	P712L	712	Missense	proximal	-1	no	18.575	18.455	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	P35612	ADD2	P17252	PRKCA	S718	P712L	712	Missense	distal	-6	no	19.678	19.644	EPSD	TCGA;ICGC;COSMIC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	Q9NRF2	SH2B1	P17252	PRKCA	S65	E70Q	70	Missense	distal	5	no	16.928	17.190	EPSD	TCGA;ICGC;COSMIC	16.704	Up-regulation
AGC_PKC_PKCa_PRKCA_ST	Q9NRF2	SH2B1	P17252	PRKCA	S65	R66C	66	Missense	proximal	1	no	16.928	14.092	EPSD	TCGA;CCLE	16.704	Loss
AGC_PKC_PKCa_PRKCA_ST	Q9NRF2	SH2B1	P17252	PRKCA	S65	S65F	65	Missense	central	0	yes	16.928	0.000	EPSD	TCGA;ICGC;COSMIC	16.704	Loss
AGC_PKC_PKCa_PRKCA_ST	Q9NRF2	SH2B1	P17252	PRKCA	S144	T143A	143	Missense	proximal	-1	no	19.824	19.643	EPSD	TCGA;ICGC;COSMIC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	Q9NRF2	SH2B1	P17252	PRKCA	S154	R156H	156	Missense	proximal	2	no	22.641	17.618	EPSD	TCGA;ICGC;COSMIC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	Q9NRF2	SH2B1	P17252	PRKCA	S154	R156L	156	Missense	proximal	2	no	22.641	17.654	EPSD	TCGA;ICGC;COSMIC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	Q9NRF2	SH2B1	P17252	PRKCA	S154	R152H	152	Missense	proximal	-2	no	22.641	18.088	EPSD	TCGA;ICGC;COSMIC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	Q9NRF2	SH2B1	P17252	PRKCA	S157	R156H	156	Missense	proximal	-1	no	17.155	16.832	EPSD	TCGA;ICGC;COSMIC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	Q9NRF2	SH2B1	P17252	PRKCA	S157	R156L	156	Missense	proximal	-1	no	17.155	16.348	EPSD	TCGA;ICGC;COSMIC	16.704	Loss
AGC_PKC_PKCa_PRKCA_ST	Q9NRF2	SH2B1	P17252	PRKCA	S157	R163Q	163	Missense	distal	6	no	17.155	17.032	EPSD	TCGA;ICGC;COSMIC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	Q9NRF2	SH2B1	P17252	PRKCA	S157	R152H	152	Missense	distal	-5	no	17.155	16.799	EPSD	TCGA;ICGC;COSMIC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	Q9NRF2	SH2B1	P17252	PRKCA	S161	R156H	156	Missense	distal	-5	no	21.126	20.771	PhosphoSitePlus;EPSD	TCGA;ICGC;COSMIC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	Q9NRF2	SH2B1	P17252	PRKCA	S161	S165L	165	Missense	distal	4	no	21.126	20.334	PhosphoSitePlus;EPSD	TCGA;ICGC;COSMIC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	Q9NRF2	SH2B1	P17252	PRKCA	S161	R156L	156	Missense	distal	-5	no	21.126	20.998	PhosphoSitePlus;EPSD	TCGA;ICGC;COSMIC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	Q9NRF2	SH2B1	P17252	PRKCA	S161	R163Q	163	Missense	proximal	2	no	21.126	17.292	PhosphoSitePlus;EPSD	TCGA;ICGC;COSMIC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	Q9NRF2	SH2B1	P17252	PRKCA	S165	S165L	165	Missense	central	0	yes	23.313	0.000	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	16.704	Loss
AGC_PKC_PKCa_PRKCA_ST	Q9NRF2	SH2B1	P17252	PRKCA	S165	R163Q	163	Missense	proximal	-2	no	23.313	21.554	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	Q9NRF2	SH2B1	P17252	PRKCA	S384	R386C	386	Missense	proximal	2	no	17.651	13.301	EPSD	TCGA;ICGC;COSMIC	16.704	Loss
AGC_PKC_PKCa_PRKCA_ST	O95786	DDX58	P17252	PRKCA	S468	Y473C	473	Missense	distal	5	no	19.174	18.557	EPSD	TCGA;COSMIC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	O95786	DDX58	P17252	PRKCA	S764	E758Q	758	Missense	distal	-6	no	17.053	16.984	EPSD	TCGA;COSMIC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	O95786	DDX58	P17252	PRKCA	S854	A860T	860	Missense	distal	6	no	16.897	16.819	EPSD	TCGA;COSMIC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	O95786	DDX58	P17252	PRKCA	S854	K849E	849	Missense	distal	-5	no	16.897	16.603	EPSD	TCGA;COSMIC	16.704	Loss
AGC_PKC_PKCa_PRKCA_ST	O95786	DDX58	P17252	PRKCA	S854	R859K	859	Missense	distal	5	no	16.897	17.041	EPSD	TCGA;COSMIC	16.704	Up-regulation
AGC_PKC_PKCa_PRKCA_ST	P07949	RET	P17252	PRKCA	S159	P155S	155	Missense	distal	-4	no	18.041	18.212	EPSD	TCGA;ICGC;COSMIC	16.704	Up-regulation
AGC_PKC_PKCa_PRKCA_ST	P07949	RET	P17252	PRKCA	S159	K161E	161	Missense	proximal	2	no	18.041	12.761	EPSD	TCGA;ICGC;COSMIC	16.704	Loss
AGC_PKC_PKCa_PRKCA_ST	P07949	RET	P17252	PRKCA	T675	E673K	673	Missense	proximal	-2	no	18.261	20.760	PhosphoSitePlus	TCGA;ICGC;COSMIC	16.704	Up-regulation
AGC_PKC_PKCa_PRKCA_ST	P07949	RET	P17252	PRKCA	T675	A672S	672	Missense	distal	-3	no	18.261	19.840	PhosphoSitePlus	TCGA;ICGC;COSMIC	16.704	Up-regulation
AGC_PKC_PKCa_PRKCA_ST	P07949	RET	P17252	PRKCA	S686	R693C	693	Missense	distal	7	no	16.759	16.536	EPSD	TCGA;ICGC	16.704	Loss
AGC_PKC_PKCa_PRKCA_ST	P07949	RET	P17252	PRKCA	S686	V685I	685	Missense	proximal	-1	no	16.759	16.939	EPSD	TCGA;ICGC;COSMIC;CCLE	16.704	Up-regulation
AGC_PKC_PKCa_PRKCA_ST	P07949	RET	P17252	PRKCA	S696	R693C	693	Missense	distal	-3	no	20.184	17.445	EPSD	TCGA;ICGC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	P07949	RET	P17252	PRKCA	S696	Q703H	703	Missense	distal	7	no	20.184	20.117	EPSD	TCGA;ICGC;COSMIC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	P07949	RET	P17252	PRKCA	S696	D698N	698	Missense	proximal	2	no	20.184	20.092	EPSD	TCGA;ICGC;COSMIC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	O15519	CFLAR	P17252	PRKCA	S193	P197H	197	Missense	distal	4	no	18.401	18.564	PhosphoSitePlus	TCGA;ICGC	16.704	Up-regulation
AGC_PKC_PKCa_PRKCA_ST	P08670	VIM	P17252	PRKCA	S2	S8L	8	Missense	distal	6	no	19.646	19.635	EPSD	TCGA;ICGC;COSMIC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	P08670	VIM	P17252	PRKCA	S5	S8L	8	Missense	distal	3	no	17.100	16.254	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	16.704	Loss
AGC_PKC_PKCa_PRKCA_ST	P08670	VIM	P17252	PRKCA	S7	S8L	8	Missense	proximal	1	no	16.941	17.767	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	16.704	Up-regulation
AGC_PKC_PKCa_PRKCA_ST	P08670	VIM	P17252	PRKCA	S8	S8L	8	Missense	central	0	yes	16.731	0.000	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	16.704	Loss
AGC_PKC_PKCa_PRKCA_ST	P08670	VIM	P17252	PRKCA	S8	F15L	15	Missense	distal	7	no	16.731	16.797	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	16.704	Up-regulation
AGC_PKC_PKCa_PRKCA_ST	P08670	VIM	P17252	PRKCA	S8	F15V	15	Missense	distal	7	no	16.731	16.738	EPSD;PhosphoSitePlus	TCGA;ICGC	16.704	Up-regulation
AGC_PKC_PKCa_PRKCA_ST	P08670	VIM	P17252	PRKCA	S9	S8L	8	Missense	proximal	-1	no	18.343	17.923	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	P08670	VIM	P17252	PRKCA	S9	F15L	15	Missense	distal	6	no	18.343	18.373	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	16.704	Up-regulation
AGC_PKC_PKCa_PRKCA_ST	P08670	VIM	P17252	PRKCA	S9	F15V	15	Missense	distal	6	no	18.343	18.295	EPSD;PhosphoSitePlus	TCGA;ICGC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	P08670	VIM	P17252	PRKCA	S10	S8L	8	Missense	proximal	-2	no	24.413	25.027	PhosphoSitePlus;EPSD	TCGA;ICGC;COSMIC	16.704	Up-regulation
AGC_PKC_PKCa_PRKCA_ST	P08670	VIM	P17252	PRKCA	S10	F15L	15	Missense	distal	5	no	24.413	24.188	PhosphoSitePlus;EPSD	TCGA;ICGC;COSMIC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	P08670	VIM	P17252	PRKCA	S10	F15V	15	Missense	distal	5	no	24.413	24.098	PhosphoSitePlus;EPSD	TCGA;ICGC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	P08670	VIM	P17252	PRKCA	S25	S22I	22	Missense	distal	-3	no	19.761	18.144	EPSD	TCGA;ICGC;COSMIC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	P08670	VIM	P17252	PRKCA	S26	S22I	22	Missense	distal	-4	no	23.535	23.093	EPSD	TCGA;ICGC;COSMIC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	P08670	VIM	P17252	PRKCA	S26	T33M	33	Missense	distal	7	no	23.535	23.539	EPSD	TCGA;ICGC;COSMIC	16.704	Up-regulation
AGC_PKC_PKCa_PRKCA_ST	P08670	VIM	P17252	PRKCA	S34	T33M	33	Missense	proximal	-1	no	16.913	17.950	EPSD	TCGA;ICGC;COSMIC	16.704	Up-regulation
AGC_PKC_PKCa_PRKCA_ST	P08670	VIM	P17252	PRKCA	S47	R50H	50	Missense	distal	3	no	16.757	16.044	EPSD	TCGA;ICGC;COSMIC	16.704	Loss
AGC_PKC_PKCa_PRKCA_ST	P08670	VIM	P17252	PRKCA	T48	R50H	50	Missense	proximal	2	no	18.727	13.704	EPSD	TCGA;ICGC;COSMIC	16.704	Loss
AGC_PKC_PKCa_PRKCA_ST	P08670	VIM	P17252	PRKCA	S55	P57R	57	Missense	proximal	2	no	12.270	17.472	EPSD	TCGA;ICGC;COSMIC	16.704	Gain
AGC_PKC_PKCa_PRKCA_ST	P08670	VIM	P17252	PRKCA	S66	R71W	71	Missense	distal	5	no	17.139	16.631	EPSD	TCGA;ICGC;COSMIC	16.704	Loss
AGC_PKC_PKCa_PRKCA_ST	P08670	VIM	P17252	PRKCA	S144	L149F	149	Missense	distal	5	no	16.594	16.819	EPSD	TCGA;ICGC;COSMIC	16.704	Gain
AGC_PKC_PKCa_PRKCA_ST	P08670	VIM	P17252	PRKCA	S205	D211H	211	Missense	distal	6	no	17.977	17.989	EPSD	TCGA;ICGC;COSMIC	16.704	Up-regulation
AGC_PKC_PKCa_PRKCA_ST	P08670	VIM	P17252	PRKCA	S226	E230K	230	Missense	distal	4	no	16.275	16.814	EPSD	TCGA;ICGC;COSMIC	16.704	Gain
AGC_PKC_PKCa_PRKCA_ST	P08670	VIM	P17252	PRKCA	S293	E288D	288	Missense	distal	-5	no	17.032	16.954	EPSD	TCGA	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	P08670	VIM	P17252	PRKCA	S293	A287T	287	Missense	distal	-6	no	17.032	16.943	EPSD	TCGA;ICGC;COSMIC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	P08670	VIM	P17252	PRKCA	S293	F295S	295	Missense	proximal	2	no	17.032	16.715	EPSD	TCGA;ICGC;COSMIC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	Q9UKF7	PITPNC1	P17252	PRKCA	S299	R296W	296	Missense	distal	-3	no	19.762	17.408	PhosphoSitePlus;EPSD	TCGA;ICGC;COSMIC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	Q04637	EIF4G1	P17252	PRKCA	S1164	G1158D	1158	Missense	distal	-6	no	16.751	16.700	EPSD	TCGA;COSMIC	16.704	Loss
AGC_PKC_PKCa_PRKCA_ST	Q13507	TRPC3	P17252	PRKCA	S251	K255N	255	Missense	distal	4	no	18.008	16.881	EPSD	TCGA;COSMIC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	P31749	AKT1	P17252	PRKCA	S124	R121W	121	Missense	distal	-3	no	16.846	14.492	EPSD	TCGA;ICGC;COSMIC	16.704	Loss
AGC_PKC_PKCa_PRKCA_ST	P31749	AKT1	P17252	PRKCA	S124	A131T	131	Missense	distal	7	no	16.846	16.854	EPSD	TCGA;ICGC;COSMIC	16.704	Up-regulation
AGC_PKC_PKCa_PRKCA_ST	P14598	NCF1	P17252	PRKCA	T93	E96K	96	Missense	distal	3	no	16.213	16.829	EPSD	TCGA;ICGC;COSMIC	16.704	Gain
AGC_PKC_PKCa_PRKCA_ST	P14598	NCF1	P17252	PRKCA	S328	F331S	331	Missense	distal	3	no	24.594	25.107	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	16.704	Up-regulation
AGC_PKC_PKCa_PRKCA_ST	Q86UR1	NOXA1	P17252	PRKCA	S239	S239F	239	Missense	central	0	yes	17.013	0.000	EPSD	TCGA;ICGC	16.704	Loss
AGC_PKC_PKCa_PRKCA_ST	Q86UR1	NOXA1	P17252	PRKCA	S461	R466Q	466	Missense	distal	5	no	17.072	17.063	EPSD	TCGA;COSMIC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	Q03721	KCNC4	P17252	PRKCA	T49	G44S	44	Missense	distal	-5	no	17.971	17.835	EPSD	TCGA;ICGC;COSMIC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	Q03721	KCNC4	P17252	PRKCA	T49	S52N	52	Missense	distal	3	no	17.971	17.793	EPSD	TCGA;ICGC;COSMIC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	Q03721	KCNC4	P17252	PRKCA	T49	E48D	48	Missense	proximal	-1	no	17.971	17.457	EPSD	TCGA;ICGC;COSMIC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	Q03721	KCNC4	P17252	PRKCA	T49	R46Q	46	Missense	distal	-3	no	17.971	15.114	EPSD	TCGA;ICGC;COSMIC;CCLE	16.704	Loss
AGC_PKC_PKCa_PRKCA_ST	Q03721	KCNC4	P17252	PRKCA	S577	A573T	573	Missense	distal	-4	no	17.833	17.085	EPSD	TCGA;ICGC;COSMIC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	Q03721	KCNC4	P17252	PRKCA	S577	R575L	575	Missense	proximal	-2	no	17.833	15.145	EPSD	TCGA;ICGC;COSMIC	16.704	Loss
AGC_PKC_PKCa_PRKCA_ST	Q03721	KCNC4	P17252	PRKCA	S577	R572Q	572	Missense	distal	-5	no	17.833	17.681	EPSD	TCGA;ICGC;COSMIC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	Q03721	KCNC4	P17252	PRKCA	S577	R576C	576	Missense	proximal	-1	no	17.833	15.173	EPSD	TCGA;ICGC;COSMIC	16.704	Loss
AGC_PKC_PKCa_PRKCA_ST	Q03721	KCNC4	P17252	PRKCA	S577	R576L	576	Missense	proximal	-1	no	17.833	17.027	EPSD	TCGA;ICGC;COSMIC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	Q03721	KCNC4	P17252	PRKCA	T578	A573T	573	Missense	distal	-5	no	21.447	21.828	EPSD	TCGA;ICGC;COSMIC	16.704	Up-regulation
AGC_PKC_PKCa_PRKCA_ST	Q03721	KCNC4	P17252	PRKCA	T578	R575L	575	Missense	distal	-3	no	21.447	17.092	EPSD	TCGA;ICGC;COSMIC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	Q03721	KCNC4	P17252	PRKCA	T578	R572Q	572	Missense	distal	-6	no	21.447	21.304	EPSD	TCGA;ICGC;COSMIC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	Q03721	KCNC4	P17252	PRKCA	T578	R576C	576	Missense	proximal	-2	no	21.447	19.748	EPSD	TCGA;ICGC;COSMIC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	Q03721	KCNC4	P17252	PRKCA	T578	R576L	576	Missense	proximal	-2	no	21.447	18.759	EPSD	TCGA;ICGC;COSMIC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	P36897	TGFBR1	P17252	PRKCA	T200	I201F	201	Missense	proximal	1	no	16.891	16.712	PhosphoSitePlus	TCGA;COSMIC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	P36897	TGFBR1	P17252	PRKCA	T200	A202V	202	Missense	proximal	2	no	16.891	16.576	PhosphoSitePlus	TCGA;COSMIC;GDSC;CCLE	16.704	Loss
AGC_PKC_PKCa_PRKCA_ST	P36897	TGFBR1	P17252	PRKCA	T200	P194S	194	Missense	distal	-6	no	16.891	16.923	PhosphoSitePlus	TCGA;COSMIC	16.704	Up-regulation
AGC_PKC_PKCa_PRKCA_ST	P46940	IQGAP1	P17252	PRKCA	S2	D5G	5	Missense	distal	3	no	18.477	19.562	EPSD	TCGA	16.704	Up-regulation
AGC_PKC_PKCa_PRKCA_ST	P46940	IQGAP1	P17252	PRKCA	S91	Y96C	96	Missense	distal	5	no	18.228	17.610	EPSD	TCGA;ICGC;COSMIC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	P46940	IQGAP1	P17252	PRKCA	S280	E278K	278	Missense	proximal	-2	no	17.016	19.515	EPSD	TCGA;ICGC;COSMIC	16.704	Up-regulation
AGC_PKC_PKCa_PRKCA_ST	P46940	IQGAP1	P17252	PRKCA	S360	S360N	360	Missense	central	0	yes	18.760	0.000	EPSD	TCGA;ICGC;COSMIC	16.704	Loss
AGC_PKC_PKCa_PRKCA_ST	P46940	IQGAP1	P17252	PRKCA	S644	G640V	640	Missense	distal	-4	no	17.321	16.758	EPSD	TCGA;COSMIC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	P46940	IQGAP1	P17252	PRKCA	S644	R647C	647	Missense	distal	3	no	17.321	14.703	EPSD	TCGA;COSMIC	16.704	Loss
AGC_PKC_PKCa_PRKCA_ST	P46940	IQGAP1	P17252	PRKCA	S1104	A1109G	1109	Missense	distal	5	no	18.161	17.918	EPSD	TCGA;ICGC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	P46940	IQGAP1	P17252	PRKCA	S1133	R1139W	1139	Missense	distal	6	no	17.028	16.780	EPSD	TCGA;COSMIC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	P46940	IQGAP1	P17252	PRKCA	S1133	A1140T	1140	Missense	distal	7	no	17.028	17.036	EPSD	TCGA;ICGC	16.704	Up-regulation
AGC_PKC_PKCa_PRKCA_ST	P46940	IQGAP1	P17252	PRKCA	S1133	M1138I	1138	Missense	distal	5	no	17.028	16.707	EPSD	TCGA;ICGC;COSMIC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	P46940	IQGAP1	P17252	PRKCA	S1227	L1225M	1225	Missense	proximal	-2	no	17.528	18.235	EPSD	TCGA	16.704	Up-regulation
AGC_PKC_PKCa_PRKCA_ST	P46940	IQGAP1	P17252	PRKCA	S1443	M1438I	1438	Missense	distal	-5	no	21.080	20.675	PhosphoSitePlus	TCGA;ICGC;COSMIC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	P46940	IQGAP1	P17252	PRKCA	S1443	D1436A	1436	Missense	distal	-7	no	21.080	21.086	PhosphoSitePlus	TCGA;ICGC;COSMIC	16.704	Up-regulation
AGC_PKC_PKCa_PRKCA_ST	P10588	NR2F6	P17252	PRKCA	S83	I84V	84	Missense	proximal	1	no	24.511	23.799	PhosphoSitePlus	TCGA;ICGC;COSMIC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	Q9UH77	KLHL3	P17252	PRKCA	S9	S10F	10	Missense	proximal	1	no	16.900	18.384	EPSD	TCGA;ICGC;COSMIC	16.704	Up-regulation
AGC_PKC_PKCa_PRKCA_ST	Q9UH77	KLHL3	P17252	PRKCA	S9	Q15H	15	Missense	distal	6	no	16.900	16.945	EPSD	TCGA;ICGC;COSMIC	16.704	Up-regulation
AGC_PKC_PKCa_PRKCA_ST	Q9UH77	KLHL3	P17252	PRKCA	S10	S10F	10	Missense	central	0	yes	17.261	0.000	EPSD	TCGA;ICGC;COSMIC	16.704	Loss
AGC_PKC_PKCa_PRKCA_ST	Q9UH77	KLHL3	P17252	PRKCA	S10	Q15H	15	Missense	distal	5	no	17.261	17.010	EPSD	TCGA;ICGC;COSMIC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	Q9UH77	KLHL3	P17252	PRKCA	S376	R383H	383	Missense	distal	7	no	17.233	17.162	EPSD	TCGA;COSMIC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	Q9UH77	KLHL3	P17252	PRKCA	S376	D372H	372	Missense	distal	-4	no	17.233	17.530	EPSD	TCGA;COSMIC	16.704	Up-regulation
AGC_PKC_PKCa_PRKCA_ST	Q9UH77	KLHL3	P17252	PRKCA	S376	M380T	380	Missense	distal	4	no	17.233	16.752	EPSD	TCGA;COSMIC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	Q9UH77	KLHL3	P17252	PRKCA	S376	T375M	375	Missense	proximal	-1	no	17.233	18.271	EPSD	TCGA;COSMIC	16.704	Up-regulation
AGC_PKC_PKCa_PRKCA_ST	Q9UH77	KLHL3	P17252	PRKCA	S433	T429M	429	Missense	distal	-4	no	18.860	19.794	PhosphoSitePlus	TCGA;COSMIC	16.704	Up-regulation
AGC_PKC_PKCa_PRKCA_ST	Q9UH77	KLHL3	P17252	PRKCA	S433	R431Q	431	Missense	proximal	-2	no	18.860	17.101	PhosphoSitePlus	TCGA;ICGC;COSMIC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	Q9UH77	KLHL3	P17252	PRKCA	S433	G437C	437	Missense	distal	4	no	18.860	18.062	PhosphoSitePlus	TCGA;ICGC;COSMIC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	Q9UH77	KLHL3	P17252	PRKCA	S433	R431W	431	Missense	proximal	-2	no	18.860	16.862	PhosphoSitePlus	TCGA;ICGC;COSMIC;CCLE	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	Q9UH77	KLHL3	P17252	PRKCA	S433	P426S	426	Missense	distal	-7	no	18.860	18.863	PhosphoSitePlus	TCGA;COSMIC	16.704	Up-regulation
AGC_PKC_PKCa_PRKCA_ST	P11234	RALB	P17252	PRKCA	S11	I18T	18	Missense	distal	7	no	16.760	16.919	EPSD	TCGA;COSMIC	16.704	Up-regulation
AGC_PKC_PKCa_PRKCA_ST	P11234	RALB	P17252	PRKCA	S11	S10N	10	Missense	proximal	-1	no	16.760	16.602	EPSD	TCGA	16.704	Loss
AGC_PKC_PKCa_PRKCA_ST	P11234	RALB	P17252	PRKCA	S50	R52T	52	Missense	proximal	2	no	20.678	15.867	EPSD	TCGA;COSMIC	16.704	Loss
AGC_PKC_PKCa_PRKCA_ST	P11234	RALB	P17252	PRKCA	S50	R52G	52	Missense	proximal	2	no	20.678	15.433	EPSD	TCGA;COSMIC	16.704	Loss
AGC_PKC_PKCa_PRKCA_ST	P11234	RALB	P17252	PRKCA	S50	K53N	53	Missense	distal	3	no	20.678	19.731	EPSD	TCGA;COSMIC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	P11234	RALB	P17252	PRKCA	S50	L57I	57	Missense	distal	7	no	20.678	20.522	EPSD	TCGA	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	P11234	RALB	P17252	PRKCA	S198	K194Q	194	Missense	distal	-4	no	18.923	18.510	PhosphoSitePlus	TCGA;COSMIC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	P11234	RALB	P17252	PRKCA	S198	S192N	192	Missense	distal	-6	no	18.923	18.866	PhosphoSitePlus	TCGA	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	P11234	RALB	P17252	PRKCA	S198	K191T	191	Missense	distal	-7	no	18.923	18.920	PhosphoSitePlus	TCGA;COSMIC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	Q13522	PPP1R1A	P17252	PRKCA	T35	R30W	30	Missense	distal	-5	no	17.620	17.306	EPSD	TCGA;ICGC;COSMIC;CCLE	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	Q13522	PPP1R1A	P17252	PRKCA	T35	T42I	42	Missense	distal	7	no	17.620	17.460	EPSD	TCGA;ICGC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	Q13522	PPP1R1A	P17252	PRKCA	S67	S62F	62	Missense	distal	-5	no	19.017	19.120	PhosphoSitePlus;EPSD	TCGA;ICGC;COSMIC	16.704	Up-regulation
AGC_PKC_PKCa_PRKCA_ST	Q13522	PPP1R1A	P17252	PRKCA	S67	R71W	71	Missense	distal	4	no	19.017	17.481	PhosphoSitePlus;EPSD	TCGA;ICGC;COSMIC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	Q13522	PPP1R1A	P17252	PRKCA	S67	S67Y	67	Missense	central	0	yes	19.017	0.000	PhosphoSitePlus;EPSD	TCGA;ICGC	16.704	Loss
AGC_PKC_PKCa_PRKCA_ST	Q13522	PPP1R1A	P17252	PRKCA	T75	T78K	78	Missense	distal	3	no	15.620	16.834	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	16.704	Gain
AGC_PKC_PKCa_PRKCA_ST	Q9BQE3	TUBA1C	P17252	PRKCA	T82	E77K	77	Missense	distal	-5	no	19.353	19.647	EPSD	TCGA	16.704	Up-regulation
AGC_PKC_PKCa_PRKCA_ST	Q9BQE3	TUBA1C	P17252	PRKCA	T82	R79C	79	Missense	distal	-3	no	19.353	16.614	EPSD	TCGA;ICGC;COSMIC	16.704	Loss
AGC_PKC_PKCa_PRKCA_ST	Q9BQE3	TUBA1C	P17252	PRKCA	S158	M154I	154	Missense	distal	-4	no	16.944	16.230	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	16.704	Loss
AGC_PKC_PKCa_PRKCA_ST	Q9BQE3	TUBA1C	P17252	PRKCA	S158	L157F	157	Missense	proximal	-1	no	16.944	16.656	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	16.704	Loss
AGC_PKC_PKCa_PRKCA_ST	Q9BQE3	TUBA1C	P17252	PRKCA	S277	E279K	279	Missense	proximal	2	no	12.521	17.800	EPSD	TCGA	16.704	Gain
AGC_PKC_PKCa_PRKCA_ST	P52566	ARHGDIB	P17252	PRKCA	T2	P8S	8	Missense	distal	6	no	17.817	17.784	EPSD	TCGA;ICGC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	P52566	ARHGDIB	P17252	PRKCA	S31	E37K	37	Missense	distal	6	no	18.603	18.697	PhosphoSitePlus	TCGA;ICGC;COSMIC	16.704	Up-regulation
AGC_PKC_PKCa_PRKCA_ST	P52566	ARHGDIB	P17252	PRKCA	S31	S31F	31	Missense	central	0	yes	18.603	0.000	PhosphoSitePlus	TCGA;ICGC;COSMIC	16.704	Loss
AGC_PKC_PKCa_PRKCA_ST	P52566	ARHGDIB	P17252	PRKCA	T129	Y130H	130	Missense	proximal	1	no	17.120	16.670	EPSD	TCGA;ICGC;COSMIC	16.704	Loss
AGC_PKC_PKCa_PRKCA_ST	P52566	ARHGDIB	P17252	PRKCA	S194	S194L	194	Missense	central	0	yes	18.678	0.000	EPSD	TCGA;ICGC;COSMIC;GDSC;CCLE	16.704	Loss
AGC_PKC_PKCa_PRKCA_ST	P52566	ARHGDIB	P17252	PRKCA	S194	E190Q	190	Missense	distal	-4	no	18.678	18.997	EPSD	TCGA;ICGC;COSMIC	16.704	Up-regulation
AGC_PKC_PKCa_PRKCA_ST	Q15139	PRKD1	P17252	PRKCA	S153	F159L	159	Missense	distal	6	no	20.548	20.578	EPSD	TCGA;ICGC;COSMIC	16.704	Up-regulation
AGC_PKC_PKCa_PRKCA_ST	Q15139	PRKD1	P17252	PRKCA	S205	R200M	200	Missense	distal	-5	no	19.048	18.881	EPSD	TCGA;ICGC;COSMIC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	Q15139	PRKD1	P17252	PRKCA	S205	V212A	212	Missense	distal	7	no	19.048	19.102	EPSD	TCGA;ICGC	16.704	Up-regulation
AGC_PKC_PKCa_PRKCA_ST	Q15139	PRKD1	P17252	PRKCA	S205	R201W	201	Missense	distal	-4	no	19.048	18.221	EPSD	TCGA;ICGC;COSMIC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	Q15139	PRKD1	P17252	PRKCA	S205	V212I	212	Missense	distal	7	no	19.048	18.951	EPSD	TCGA;ICGC;COSMIC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	Q15139	PRKD1	P17252	PRKCA	S412	K414N	414	Missense	proximal	2	no	20.971	16.022	EPSD	TCGA	16.704	Loss
AGC_PKC_PKCa_PRKCA_ST	Q15139	PRKD1	P17252	PRKCA	S412	L406I	406	Missense	distal	-6	no	20.971	20.939	EPSD	TCGA;COSMIC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	Q15139	PRKD1	P17252	PRKCA	S420	K414N	414	Missense	distal	-6	no	17.272	17.148	EPSD	TCGA	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	Q15139	PRKD1	P17252	PRKCA	S421	K414N	414	Missense	distal	-7	no	18.202	18.197	EPSD	TCGA	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	Q15139	PRKD1	P17252	PRKCA	S738	R740Q	740	Missense	proximal	2	no	20.313	16.479	PhosphoSitePlus;EPSD	TCGA;ICGC;COSMIC	16.704	Loss
AGC_PKC_PKCa_PRKCA_ST	Q15139	PRKD1	P17252	PRKCA	S738	R732Q	732	Missense	distal	-6	no	20.313	20.170	PhosphoSitePlus;EPSD	TCGA;COSMIC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	Q15139	PRKD1	P17252	PRKCA	S738	R732L	732	Missense	distal	-6	no	20.313	20.174	PhosphoSitePlus;EPSD	TCGA;COSMIC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	Q15139	PRKD1	P17252	PRKCA	S738	R732W	732	Missense	distal	-6	no	20.313	20.028	PhosphoSitePlus;EPSD	TCGA;COSMIC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	Q15139	PRKD1	P17252	PRKCA	S742	R740Q	740	Missense	proximal	-2	no	19.960	18.201	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	Q15139	PRKD1	P17252	PRKCA	S742	P747T	747	Missense	distal	5	no	19.960	19.625	EPSD;PhosphoSitePlus	TCGA;COSMIC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	Q15139	PRKD1	P17252	PRKCA	S742	A748S	748	Missense	distal	6	no	19.960	19.931	EPSD;PhosphoSitePlus	TCGA;COSMIC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	Q15139	PRKD1	P17252	PRKCA	S742	T746A	746	Missense	distal	4	no	19.960	20.407	EPSD;PhosphoSitePlus	TCGA	16.704	Up-regulation
AGC_PKC_PKCa_PRKCA_ST	Q15139	PRKD1	P17252	PRKCA	S829	V822L	822	Missense	distal	-7	no	19.730	19.733	EPSD	TCGA;COSMIC	16.704	Up-regulation
AGC_PKC_PKCa_PRKCA_ST	Q15139	PRKD1	P17252	PRKCA	S829	R827H	827	Missense	proximal	-2	no	19.730	15.177	EPSD	TCGA;COSMIC	16.704	Loss
AGC_PKC_PKCa_PRKCA_ST	Q15139	PRKD1	P17252	PRKCA	S829	H836N	836	Missense	distal	7	no	19.730	19.732	EPSD	TCGA;COSMIC	16.704	Up-regulation
AGC_PKC_PKCa_PRKCA_ST	Q15139	PRKD1	P17252	PRKCA	S829	H836L	836	Missense	distal	7	no	19.730	19.758	EPSD	TCGA;COSMIC	16.704	Up-regulation
AGC_PKC_PKCa_PRKCA_ST	Q15139	PRKD1	P17252	PRKCA	S829	R827C	827	Missense	proximal	-2	no	19.730	18.031	EPSD	TCGA;COSMIC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	Q15139	PRKD1	P17252	PRKCA	S829	K826N	826	Missense	distal	-3	no	19.730	17.530	EPSD	TCGA	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	P55087	AQP4	P17252	PRKCA	S180	D184H	184	Missense	distal	4	no	22.148	22.465	PhosphoSitePlus	TCGA;ICGC;COSMIC	16.704	Up-regulation
AGC_PKC_PKCa_PRKCA_ST	P55087	AQP4	P17252	PRKCA	S180	T186S	186	Missense	distal	6	no	22.148	22.197	PhosphoSitePlus	TCGA;ICGC;COSMIC	16.704	Up-regulation
AGC_PKC_PKCa_PRKCA_ST	P55087	AQP4	P17252	PRKCA	S180	C178W	178	Missense	proximal	-2	no	22.148	21.851	PhosphoSitePlus	TCGA;ICGC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	P17302	GJA1	P17252	PRKCA	S262	Q263K	263	Missense	proximal	1	no	18.371	18.526	EPSD	TCGA;ICGC;COSMIC	16.704	Up-regulation
AGC_PKC_PKCa_PRKCA_ST	P17302	GJA1	P17252	PRKCA	S262	F268S	268	Missense	distal	6	no	18.371	18.413	EPSD	TCGA;ICGC;COSMIC	16.704	Up-regulation
AGC_PKC_PKCa_PRKCA_ST	P17302	GJA1	P17252	PRKCA	S262	G261V	261	Missense	proximal	-1	no	18.371	16.661	EPSD	TCGA;ICGC;COSMIC	16.704	Loss
AGC_PKC_PKCa_PRKCA_ST	P17302	GJA1	P17252	PRKCA	S296	R299H	299	Missense	distal	3	no	17.041	16.329	EPSD	TCGA;COSMIC	16.704	Loss
AGC_PKC_PKCa_PRKCA_ST	P17302	GJA1	P17252	PRKCA	S296	R293K	293	Missense	distal	-3	no	17.041	15.015	EPSD	TCGA;ICGC;COSMIC	16.704	Loss
AGC_PKC_PKCa_PRKCA_ST	P17302	GJA1	P17252	PRKCA	S296	C298S	298	Missense	proximal	2	no	17.041	16.772	EPSD	TCGA;ICGC;COSMIC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	P17302	GJA1	P17252	PRKCA	S296	S296F	296	Missense	central	0	yes	17.041	0.000	EPSD	TCGA;ICGC;COSMIC	16.704	Loss
AGC_PKC_PKCa_PRKCA_ST	P17302	GJA1	P17252	PRKCA	S296	S296Y	296	Missense	central	0	yes	17.041	0.000	EPSD	TCGA;ICGC	16.704	Loss
AGC_PKC_PKCa_PRKCA_ST	P17302	GJA1	P17252	PRKCA	S344	Q342R	342	Missense	proximal	-2	no	18.437	20.196	EPSD	TCGA;ICGC;COSMIC	16.704	Up-regulation
AGC_PKC_PKCa_PRKCA_ST	P17302	GJA1	P17252	PRKCA	S344	D340N	340	Missense	distal	-4	no	18.437	18.785	EPSD	TCGA;ICGC;COSMIC	16.704	Up-regulation
AGC_PKC_PKCa_PRKCA_ST	P17302	GJA1	P17252	PRKCA	S344	G350E	350	Missense	distal	6	no	18.437	18.480	EPSD	TCGA;ICGC;COSMIC	16.704	Up-regulation
AGC_PKC_PKCa_PRKCA_ST	P17302	GJA1	P17252	PRKCA	S344	N343H	343	Missense	proximal	-1	no	18.437	18.659	EPSD	TCGA;ICGC;COSMIC	16.704	Up-regulation
AGC_PKC_PKCa_PRKCA_ST	P17302	GJA1	P17252	PRKCA	S344	A348T	348	Missense	distal	4	no	18.437	17.990	EPSD	TCGA;ICGC;COSMIC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	P17302	GJA1	P17252	PRKCA	S364	V359L	359	Missense	distal	-5	no	19.138	19.574	EPSD	TCGA;ICGC;COSMIC	16.704	Up-regulation
AGC_PKC_PKCa_PRKCA_ST	P17302	GJA1	P17252	PRKCA	S364	S369N	369	Missense	distal	5	no	19.138	18.917	EPSD	TCGA;ICGC;COSMIC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	P17302	GJA1	P17252	PRKCA	S368	S369N	369	Missense	proximal	1	no	19.498	19.545	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	16.704	Up-regulation
AGC_PKC_PKCa_PRKCA_ST	P17302	GJA1	P17252	PRKCA	S372	S369N	369	Missense	distal	-3	no	19.465	18.108	PhosphoSitePlus;EPSD	TCGA;ICGC;COSMIC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	P17302	GJA1	P17252	PRKCA	S373	S369N	369	Missense	distal	-4	no	16.953	16.623	EPSD	TCGA;ICGC;COSMIC	16.704	Loss
AGC_PKC_PKCa_PRKCA_ST	P00533	EGFR	P17252	PRKCA	S227	C223Y	223	Missense	distal	-4	no	16.405	17.362	EPSD	TCGA;COSMIC	16.704	Gain
AGC_PKC_PKCa_PRKCA_ST	P00533	EGFR	P17252	PRKCA	S227	P228L	228	Missense	proximal	1	no	16.405	16.832	EPSD	TCGA;COSMIC	16.704	Gain
AGC_PKC_PKCa_PRKCA_ST	P00533	EGFR	P17252	PRKCA	T678	R675W	675	Missense	distal	-3	no	23.102	20.748	PhosphoSitePlus	TCGA	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	P00533	EGFR	P17252	PRKCA	T678	R677H	677	Missense	proximal	-1	no	23.102	22.779	PhosphoSitePlus	TCGA;COSMIC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	P00533	EGFR	P17252	PRKCA	T678	R681M	681	Missense	distal	3	no	23.102	21.834	PhosphoSitePlus	TCGA	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	P00533	EGFR	P17252	PRKCA	T678	Q684H	684	Missense	distal	6	no	23.102	23.147	PhosphoSitePlus	TCGA	16.704	Up-regulation
AGC_PKC_PKCa_PRKCA_ST	P00533	EGFR	P17252	PRKCA	T678	T678M	678	Missense	central	0	yes	23.102	0.000	PhosphoSitePlus	TCGA;GDSC;CCLE	16.704	Loss
AGC_PKC_PKCa_PRKCA_ST	P00533	EGFR	P17252	PRKCA	S752	P753L	753	Missense	proximal	1	no	16.571	16.998	EPSD	TCGA;COSMIC	16.704	Gain
AGC_PKC_PKCa_PRKCA_ST	P00533	EGFR	P17252	PRKCA	S1162	S1162C	1162	Missense	central	0	yes	16.914	0.000	EPSD	TCGA;ICGC;COSMIC	16.704	Loss
AGC_PKC_PKCa_PRKCA_ST	P00533	EGFR	P17252	PRKCA	S1162	L1167M	1167	Missense	distal	5	no	16.914	17.232	EPSD	TCGA;ICGC;COSMIC	16.704	Up-regulation
AGC_PKC_PKCa_PRKCA_ST	Q8WTQ7	GRK7	P17252	PRKCA	S23	D26N	26	Missense	distal	3	no	20.795	20.950	EPSD	TCGA;ICGC;COSMIC	16.704	Up-regulation
AGC_PKC_PKCa_PRKCA_ST	Q8WTQ7	GRK7	P17252	PRKCA	S23	Q18H	18	Missense	distal	-5	no	20.795	20.592	EPSD	TCGA;ICGC;COSMIC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	Q8WTQ7	GRK7	P17252	PRKCA	S23	D24N	24	Missense	proximal	1	no	20.795	21.267	EPSD	TCGA;ICGC;COSMIC	16.704	Up-regulation
AGC_PKC_PKCa_PRKCA_ST	Q8WTQ7	GRK7	P17252	PRKCA	S23	S23L	23	Missense	central	0	yes	20.795	0.000	EPSD	TCGA;ICGC;COSMIC	16.704	Loss
AGC_PKC_PKCa_PRKCA_ST	Q8WTQ7	GRK7	P17252	PRKCA	S23	R20W	20	Missense	distal	-3	no	20.795	18.441	EPSD	TCGA;ICGC;COSMIC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	Q8WTQ7	GRK7	P17252	PRKCA	S36	R32W	32	Missense	distal	-4	no	21.178	20.352	PhosphoSitePlus	TCGA;ICGC;COSMIC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	Q8WTQ7	GRK7	P17252	PRKCA	S36	R32Q	32	Missense	distal	-4	no	21.178	20.801	PhosphoSitePlus	TCGA;ICGC;COSMIC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	Q8WTQ7	GRK7	P17252	PRKCA	S36	R35C	35	Missense	proximal	-1	no	21.178	18.518	PhosphoSitePlus	TCGA;ICGC;COSMIC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	P02786	TFRC	P17252	PRKCA	S7	F9L	9	Missense	proximal	2	no	17.729	17.045	EPSD	TCGA;ICGC;COSMIC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	P02786	TFRC	P17252	PRKCA	S10	F9L	9	Missense	proximal	-1	no	16.478	16.766	EPSD	TCGA;ICGC;COSMIC	16.704	Gain
AGC_PKC_PKCa_PRKCA_ST	P02786	TFRC	P17252	PRKCA	S24	R27W	27	Missense	distal	3	no	19.213	16.279	PhosphoSitePlus	TCGA;ICGC;COSMIC	16.704	Loss
AGC_PKC_PKCa_PRKCA_ST	P02786	TFRC	P17252	PRKCA	S24	T21A	21	Missense	distal	-3	no	19.213	18.927	PhosphoSitePlus	TCGA;ICGC;COSMIC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	P02786	TFRC	P17252	PRKCA	S132	S132L	132	Missense	central	0	yes	21.336	0.000	EPSD	TCGA;ICGC;COSMIC;CCLE	16.704	Loss
AGC_PKC_PKCa_PRKCA_ST	P02786	TFRC	P17252	PRKCA	S691	H684L	684	Missense	distal	-7	no	17.785	17.781	EPSD	TCGA;ICGC;COSMIC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	P02786	TFRC	P17252	PRKCA	S691	S695F	695	Missense	distal	4	no	17.785	17.423	EPSD	TCGA;ICGC;COSMIC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	P02786	TFRC	P17252	PRKCA	S691	V690I	690	Missense	proximal	-1	no	17.785	17.964	EPSD	TCGA;ICGC;COSMIC;GDSC;CCLE	16.704	Up-regulation
AGC_PKC_PKCa_PRKCA_ST	P10721	KIT	P17252	PRKCA	S147	P141S	141	Missense	distal	-6	no	17.343	17.375	EPSD	TCGA;ICGC;COSMIC	16.704	Up-regulation
AGC_PKC_PKCa_PRKCA_ST	P10721	KIT	P17252	PRKCA	S741	A736T	736	Missense	distal	-5	no	22.542	22.923	PhosphoSitePlus;EPSD	TCGA;ICGC;COSMIC	16.704	Up-regulation
AGC_PKC_PKCa_PRKCA_ST	P10721	KIT	P17252	PRKCA	S741	T734A	734	Missense	distal	-7	no	22.542	22.547	PhosphoSitePlus;EPSD	TCGA;ICGC	16.704	Up-regulation
AGC_PKC_PKCa_PRKCA_ST	P10721	KIT	P17252	PRKCA	S741	S741Y	741	Missense	central	0	yes	22.542	0.000	PhosphoSitePlus;EPSD	TCGA;ICGC;COSMIC	16.704	Loss
AGC_PKC_PKCa_PRKCA_ST	P10721	KIT	P17252	PRKCA	S741	R739K	739	Missense	proximal	-2	no	22.542	20.915	PhosphoSitePlus;EPSD	TCGA;ICGC;COSMIC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	P10721	KIT	P17252	PRKCA	S741	D737N	737	Missense	distal	-4	no	22.542	22.891	PhosphoSitePlus;EPSD	TCGA;ICGC;COSMIC	16.704	Up-regulation
AGC_PKC_PKCa_PRKCA_ST	P10721	KIT	P17252	PRKCA	S746	T753A	753	Missense	distal	7	no	17.714	17.706	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	P10721	KIT	P17252	PRKCA	S746	S741Y	741	Missense	distal	-5	no	17.714	17.632	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	P10721	KIT	P17252	PRKCA	S746	R739K	739	Missense	distal	-7	no	17.714	17.709	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	P10721	KIT	P17252	PRKCA	S891	R888Q	888	Missense	distal	-3	no	17.821	14.963	EPSD	TCGA;ICGC;COSMIC	16.704	Loss
AGC_PKC_PKCa_PRKCA_ST	P10721	KIT	P17252	PRKCA	S891	R888L	888	Missense	distal	-3	no	17.821	13.465	EPSD	TCGA;ICGC;COSMIC	16.704	Loss
AGC_PKC_PKCa_PRKCA_ST	P10721	KIT	P17252	PRKCA	S891	A895T	895	Missense	distal	4	no	17.821	17.373	EPSD	TCGA;ICGC;COSMIC;GDSC;CCLE	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	Q9BR76	CORO1B	P17252	PRKCA	T209	R207W	207	Missense	proximal	-2	no	18.749	16.752	EPSD	TCGA;ICGC;COSMIC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	Q9BR76	CORO1B	P17252	PRKCA	T209	G208D	208	Missense	proximal	-1	no	18.749	18.006	EPSD	TCGA;ICGC;COSMIC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	Q13131	PRKAA1	P17252	PRKCA	S5	R2H	2	Missense	distal	-3	no	23.059	19.203	EPSD	TCGA;ICGC;COSMIC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	Q13131	PRKAA1	P17252	PRKCA	S6	R2H	2	Missense	distal	-4	no	27.207	26.633	EPSD	TCGA;ICGC;COSMIC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	O60928	KCNJ13	P17252	PRKCA	S14	V8G	8	Missense	distal	-6	no	20.336	20.416	EPSD	TCGA;ICGC	16.704	Up-regulation
AGC_PKC_PKCa_PRKCA_ST	O60928	KCNJ13	P17252	PRKCA	S201	V202D	202	Missense	proximal	1	no	19.346	17.969	PhosphoSitePlus	TCGA;ICGC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	O60928	KCNJ13	P17252	PRKCA	S287	E280K	280	Missense	distal	-7	no	19.566	19.574	EPSD	TCGA;ICGC;COSMIC	16.704	Up-regulation
AGC_PKC_PKCa_PRKCA_ST	O60928	KCNJ13	P17252	PRKCA	S287	C282R	282	Missense	distal	-5	no	19.566	20.242	EPSD	TCGA;ICGC;COSMIC	16.704	Up-regulation
AGC_PKC_PKCa_PRKCA_ST	O60928	KCNJ13	P17252	PRKCA	S287	C282Y	282	Missense	distal	-5	no	19.566	19.733	EPSD	TCGA;ICGC;COSMIC	16.704	Up-regulation
AGC_PKC_PKCa_PRKCA_ST	Q13976	PRKG1	P17252	PRKCA	S27	E32D	32	Missense	distal	5	no	23.289	23.197	EPSD	TCGA;COSMIC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	O75376	NCOR1	P17252	PRKCA	S70	R66L	66	Missense	distal	-4	no	21.046	20.422	PhosphoSitePlus	TCGA;ICGC;COSMIC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	O75376	NCOR1	P17252	PRKCA	S70	Q63H	63	Missense	distal	-7	no	21.046	21.048	PhosphoSitePlus	TCGA;ICGC;COSMIC	16.704	Up-regulation
AGC_PKC_PKCa_PRKCA_ST	O75376	NCOR1	P17252	PRKCA	S70	R66Q	66	Missense	distal	-4	no	21.046	20.669	PhosphoSitePlus	TCGA;ICGC;COSMIC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	O75376	NCOR1	P17252	PRKCA	S88	R86I	86	Missense	proximal	-2	no	17.988	14.400	EPSD	TCGA;ICGC;COSMIC	16.704	Loss
AGC_PKC_PKCa_PRKCA_ST	O75376	NCOR1	P17252	PRKCA	S88	E90K	90	Missense	proximal	2	no	17.988	23.267	EPSD	TCGA;ICGC;COSMIC	16.704	Up-regulation
AGC_PKC_PKCa_PRKCA_ST	O75376	NCOR1	P17252	PRKCA	S88	P91S	91	Missense	distal	3	no	17.988	18.128	EPSD	TCGA;ICGC;COSMIC	16.704	Up-regulation
AGC_PKC_PKCa_PRKCA_ST	O75376	NCOR1	P17252	PRKCA	S106	S106L	106	Missense	central	0	yes	20.474	0.000	EPSD	TCGA;ICGC;COSMIC	16.704	Loss
AGC_PKC_PKCa_PRKCA_ST	O75376	NCOR1	P17252	PRKCA	S106	K107N	107	Missense	proximal	1	no	20.474	19.309	EPSD	TCGA;ICGC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	O75376	NCOR1	P17252	PRKCA	S106	L104P	104	Missense	proximal	-2	no	20.474	20.119	EPSD	TCGA;ICGC;COSMIC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	O75376	NCOR1	P17252	PRKCA	S106	S103L	103	Missense	distal	-3	no	20.474	18.988	EPSD	TCGA;ICGC;COSMIC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	O75376	NCOR1	P17252	PRKCA	S401	S401C	401	Missense	central	0	yes	19.239	0.000	EPSD	TCGA;ICGC;COSMIC	16.704	Loss
AGC_PKC_PKCa_PRKCA_ST	O75376	NCOR1	P17252	PRKCA	S401	L400F	400	Missense	proximal	-1	no	19.239	18.951	EPSD	TCGA;ICGC;COSMIC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	O75376	NCOR1	P17252	PRKCA	T568	R570L	570	Missense	proximal	2	no	18.285	13.298	EPSD	TCGA;ICGC;COSMIC	16.704	Loss
AGC_PKC_PKCa_PRKCA_ST	O75376	NCOR1	P17252	PRKCA	T568	E562K	562	Missense	distal	-6	no	18.285	18.353	EPSD	TCGA;ICGC;COSMIC	16.704	Up-regulation
AGC_PKC_PKCa_PRKCA_ST	O75376	NCOR1	P17252	PRKCA	T568	P569L	569	Missense	proximal	1	no	18.285	18.712	EPSD	TCGA;ICGC;COSMIC	16.704	Up-regulation
AGC_PKC_PKCa_PRKCA_ST	O75376	NCOR1	P17252	PRKCA	T568	R570Q	570	Missense	proximal	2	no	18.285	14.451	EPSD	TCGA;ICGC;COSMIC	16.704	Loss
AGC_PKC_PKCa_PRKCA_ST	O75376	NCOR1	P17252	PRKCA	S990	C987Y	987	Missense	distal	-3	no	17.717	15.896	EPSD	TCGA;COSMIC	16.704	Loss
AGC_PKC_PKCa_PRKCA_ST	O75376	NCOR1	P17252	PRKCA	S990	S992R	992	Missense	proximal	2	no	17.717	22.337	EPSD	TCGA	16.704	Up-regulation
AGC_PKC_PKCa_PRKCA_ST	O75376	NCOR1	P17252	PRKCA	S1111	F1110C	1110	Missense	proximal	-1	no	17.357	15.792	EPSD	TCGA	16.704	Loss
AGC_PKC_PKCa_PRKCA_ST	O75376	NCOR1	P17252	PRKCA	S1160	S1154L	1154	Missense	distal	-6	no	19.776	19.710	EPSD	TCGA;COSMIC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	O75376	NCOR1	P17252	PRKCA	S1186	S1186F	1186	Missense	central	0	yes	18.612	0.000	EPSD	TCGA;COSMIC	16.704	Loss
AGC_PKC_PKCa_PRKCA_ST	O75376	NCOR1	P17252	PRKCA	S1186	K1184N	1184	Missense	proximal	-2	no	18.612	17.043	EPSD	TCGA;COSMIC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	O75376	NCOR1	P17252	PRKCA	T1232	E1230K	1230	Missense	proximal	-2	no	15.050	17.549	EPSD	TCGA;COSMIC;GDSC;CCLE	16.704	Gain
AGC_PKC_PKCa_PRKCA_ST	O75376	NCOR1	P17252	PRKCA	S1234	E1230K	1230	Missense	distal	-4	no	19.627	20.358	EPSD	TCGA;COSMIC;GDSC;CCLE	16.704	Up-regulation
AGC_PKC_PKCa_PRKCA_ST	O75376	NCOR1	P17252	PRKCA	S1234	G1231R	1231	Missense	distal	-3	no	19.627	22.889	EPSD	TCGA;COSMIC	16.704	Up-regulation
AGC_PKC_PKCa_PRKCA_ST	O75376	NCOR1	P17252	PRKCA	S1259	R1261G	1261	Missense	proximal	2	no	20.302	15.057	EPSD	TCGA	16.704	Loss
AGC_PKC_PKCa_PRKCA_ST	O75376	NCOR1	P17252	PRKCA	S1263	R1261G	1261	Missense	proximal	-2	no	18.160	15.288	EPSD	TCGA	16.704	Loss
AGC_PKC_PKCa_PRKCA_ST	O75376	NCOR1	P17252	PRKCA	S1263	P1268L	1268	Missense	distal	5	no	18.160	17.810	EPSD	TCGA;COSMIC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	O75376	NCOR1	P17252	PRKCA	S1307	E1309K	1309	Missense	proximal	2	no	12.913	18.192	EPSD	TCGA;COSMIC	16.704	Gain
AGC_PKC_PKCa_PRKCA_ST	O75376	NCOR1	P17252	PRKCA	S1322	R1326Q	1326	Missense	distal	4	no	17.249	17.031	EPSD	TCGA;COSMIC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	O75376	NCOR1	P17252	PRKCA	S1322	A1327T	1327	Missense	distal	5	no	17.249	16.970	EPSD	TCGA;COSMIC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	O75376	NCOR1	P17252	PRKCA	S1364	Q1357R	1357	Missense	distal	-7	no	18.060	18.068	EPSD	TCGA;COSMIC	16.704	Up-regulation
AGC_PKC_PKCa_PRKCA_ST	O75376	NCOR1	P17252	PRKCA	S1364	D1358H	1358	Missense	distal	-6	no	18.060	18.150	EPSD	TCGA;COSMIC	16.704	Up-regulation
AGC_PKC_PKCa_PRKCA_ST	O75376	NCOR1	P17252	PRKCA	S1373	T1374A	1374	Missense	proximal	1	no	16.276	16.747	EPSD	TCGA;COSMIC	16.704	Gain
AGC_PKC_PKCa_PRKCA_ST	O75376	NCOR1	P17252	PRKCA	T1443	R1447Q	1447	Missense	distal	4	no	16.827	16.610	EPSD	TCGA;COSMIC;GDSC;CCLE	16.704	Loss
AGC_PKC_PKCa_PRKCA_ST	O75376	NCOR1	P17252	PRKCA	T1443	S1446F	1446	Missense	distal	3	no	16.827	16.314	EPSD	TCGA	16.704	Loss
AGC_PKC_PKCa_PRKCA_ST	O75376	NCOR1	P17252	PRKCA	T1443	R1445C	1445	Missense	proximal	2	no	16.827	12.477	EPSD	TCGA;COSMIC	16.704	Loss
AGC_PKC_PKCa_PRKCA_ST	O75376	NCOR1	P17252	PRKCA	S1480	P1485H	1485	Missense	distal	5	no	17.271	16.994	EPSD	TCGA;COSMIC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	O75376	NCOR1	P17252	PRKCA	S1480	R1482W	1482	Missense	proximal	2	no	17.271	11.831	EPSD	TCGA;COSMIC	16.704	Loss
AGC_PKC_PKCa_PRKCA_ST	O75376	NCOR1	P17252	PRKCA	S1480	T1479I	1479	Missense	proximal	-1	no	17.271	16.366	EPSD	TCGA;COSMIC	16.704	Loss
AGC_PKC_PKCa_PRKCA_ST	O75376	NCOR1	P17252	PRKCA	S1480	V1486A	1486	Missense	distal	6	no	17.271	17.390	EPSD	TCGA;COSMIC	16.704	Up-regulation
AGC_PKC_PKCa_PRKCA_ST	O75376	NCOR1	P17252	PRKCA	S1496	T1502S	1502	Missense	distal	6	no	18.642	18.690	EPSD	TCGA;COSMIC	16.704	Up-regulation
AGC_PKC_PKCa_PRKCA_ST	O75376	NCOR1	P17252	PRKCA	T1520	S1519L	1519	Missense	proximal	-1	no	16.714	16.295	EPSD	TCGA;COSMIC	16.704	Loss
AGC_PKC_PKCa_PRKCA_ST	O75376	NCOR1	P17252	PRKCA	T1520	H1515Y	1515	Missense	distal	-5	no	16.714	16.561	EPSD	TCGA;COSMIC	16.704	Loss
AGC_PKC_PKCa_PRKCA_ST	O75376	NCOR1	P17252	PRKCA	T1524	A1531V	1531	Missense	distal	7	no	17.189	17.134	EPSD	TCGA;COSMIC;GDSC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	O75376	NCOR1	P17252	PRKCA	T1524	S1519L	1519	Missense	distal	-5	no	17.189	17.488	EPSD	TCGA;COSMIC	16.704	Up-regulation
AGC_PKC_PKCa_PRKCA_ST	O75376	NCOR1	P17252	PRKCA	S1528	A1531V	1531	Missense	distal	3	no	18.458	18.202	EPSD	TCGA;COSMIC;GDSC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	O75376	NCOR1	P17252	PRKCA	S1554	R1561Q	1561	Missense	distal	7	no	16.797	16.792	EPSD	TCGA;COSMIC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	O75376	NCOR1	P17252	PRKCA	S1554	A1556V	1556	Missense	proximal	2	no	16.797	16.481	EPSD	TCGA;COSMIC	16.704	Loss
AGC_PKC_PKCa_PRKCA_ST	O75376	NCOR1	P17252	PRKCA	S1554	G1557D	1557	Missense	distal	3	no	16.797	15.711	EPSD	TCGA	16.704	Loss
AGC_PKC_PKCa_PRKCA_ST	O75376	NCOR1	P17252	PRKCA	S1554	S1554I	1554	Missense	central	0	yes	16.797	0.000	EPSD	TCGA;COSMIC	16.704	Loss
AGC_PKC_PKCa_PRKCA_ST	O75376	NCOR1	P17252	PRKCA	S1636	E1639G	1639	Missense	distal	3	no	21.557	22.156	EPSD	TCGA;COSMIC	16.704	Up-regulation
AGC_PKC_PKCa_PRKCA_ST	O75376	NCOR1	P17252	PRKCA	S1695	S1697F	1697	Missense	proximal	2	no	16.938	17.254	EPSD	TCGA	16.704	Up-regulation
AGC_PKC_PKCa_PRKCA_ST	O75376	NCOR1	P17252	PRKCA	S1742	P1740L	1740	Missense	proximal	-2	no	17.305	17.659	EPSD	TCGA;COSMIC	16.704	Up-regulation
AGC_PKC_PKCa_PRKCA_ST	O75376	NCOR1	P17252	PRKCA	S1760	R1755C	1755	Missense	distal	-5	no	17.669	16.993	EPSD	TCGA;COSMIC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	O75376	NCOR1	P17252	PRKCA	S1963	S1970R	1970	Missense	distal	7	no	17.446	17.492	EPSD	TCGA	16.704	Up-regulation
AGC_PKC_PKCa_PRKCA_ST	O75376	NCOR1	P17252	PRKCA	T1968	S1970R	1970	Missense	proximal	2	no	13.244	17.864	EPSD	TCGA	16.704	Gain
AGC_PKC_PKCa_PRKCA_ST	O75376	NCOR1	P17252	PRKCA	S2023	H2016Y	2016	Missense	distal	-7	no	16.886	16.888	EPSD	TCGA;COSMIC	16.704	Up-regulation
AGC_PKC_PKCa_PRKCA_ST	O75376	NCOR1	P17252	PRKCA	S2069	Q2071K	2071	Missense	proximal	2	no	14.137	17.550	EPSD	TCGA;COSMIC	16.704	Gain
AGC_PKC_PKCa_PRKCA_ST	O75376	NCOR1	P17252	PRKCA	S2098	S2098L	2098	Missense	central	0	yes	17.497	0.000	EPSD	TCGA;COSMIC	16.704	Loss
AGC_PKC_PKCa_PRKCA_ST	O75376	NCOR1	P17252	PRKCA	S2098	V2093A	2093	Missense	distal	-5	no	17.497	17.581	EPSD	TCGA;COSMIC	16.704	Up-regulation
AGC_PKC_PKCa_PRKCA_ST	O75376	NCOR1	P17252	PRKCA	S2098	R2100C	2100	Missense	proximal	2	no	17.497	13.147	EPSD	TCGA;COSMIC	16.704	Loss
AGC_PKC_PKCa_PRKCA_ST	O75376	NCOR1	P17252	PRKCA	S2105	Q2108R	2108	Missense	distal	3	no	15.017	17.471	EPSD	TCGA;COSMIC	16.704	Gain
AGC_PKC_PKCa_PRKCA_ST	O75376	NCOR1	P17252	PRKCA	S2117	R2114T	2114	Missense	distal	-3	no	17.620	13.456	EPSD	TCGA;COSMIC	16.704	Loss
AGC_PKC_PKCa_PRKCA_ST	O75376	NCOR1	P17252	PRKCA	S2131	R2129K	2129	Missense	proximal	-2	no	18.522	16.894	EPSD	TCGA;COSMIC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	O75376	NCOR1	P17252	PRKCA	S2131	P2137T	2137	Missense	distal	6	no	18.522	18.440	EPSD	TCGA	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	O75376	NCOR1	P17252	PRKCA	S2169	L2167I	2167	Missense	proximal	-2	no	18.482	17.582	EPSD	TCGA;COSMIC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	O75376	NCOR1	P17252	PRKCA	S2253	S2249C	2249	Missense	distal	-4	no	19.056	17.905	EPSD	TCGA;COSMIC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	O75376	NCOR1	P17252	PRKCA	S2253	N2260K	2260	Missense	distal	7	no	19.056	19.176	EPSD	TCGA;COSMIC	16.704	Up-regulation
AGC_PKC_PKCa_PRKCA_ST	O75376	NCOR1	P17252	PRKCA	S2253	G2251C	2251	Missense	proximal	-2	no	19.056	20.228	EPSD	TCGA;COSMIC	16.704	Up-regulation
AGC_PKC_PKCa_PRKCA_ST	O75376	NCOR1	P17252	PRKCA	S2253	F2254S	2254	Missense	proximal	1	no	19.056	17.572	EPSD	TCGA;COSMIC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	O75376	NCOR1	P17252	PRKCA	S2335	N2331H	2331	Missense	distal	-4	no	17.167	17.116	EPSD	TCGA;COSMIC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	O75376	NCOR1	P17252	PRKCA	S2335	K2334T	2334	Missense	proximal	-1	no	17.167	16.345	EPSD	TCGA;COSMIC	16.704	Loss
AGC_PKC_PKCa_PRKCA_ST	O75376	NCOR1	P17252	PRKCA	S2335	G2341V	2341	Missense	distal	6	no	17.167	17.156	EPSD	TCGA;COSMIC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	O75376	NCOR1	P17252	PRKCA	S2335	S2335Y	2335	Missense	central	0	yes	17.167	0.000	EPSD	TCGA;COSMIC	16.704	Loss
AGC_PKC_PKCa_PRKCA_ST	O75376	NCOR1	P17252	PRKCA	S2394	P2397L	2397	Missense	distal	3	no	18.118	17.411	EPSD	TCGA;COSMIC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	O75376	NCOR1	P17252	PRKCA	S2394	R2391Q	2391	Missense	distal	-3	no	18.118	15.260	EPSD	TCGA;COSMIC	16.704	Loss
AGC_PKC_PKCa_PRKCA_ST	O75376	NCOR1	P17252	PRKCA	S2394	R2391G	2391	Missense	distal	-3	no	18.118	14.856	EPSD	TCGA;COSMIC	16.704	Loss
AGC_PKC_PKCa_PRKCA_ST	O75376	NCOR1	P17252	PRKCA	S2394	T2389I	2389	Missense	distal	-5	no	18.118	17.645	EPSD	TCGA	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	O75376	NCOR1	P17252	PRKCA	S2394	P2398S	2398	Missense	distal	4	no	18.118	18.318	EPSD	TCGA;COSMIC	16.704	Up-regulation
AGC_PKC_PKCa_PRKCA_ST	Q9UQ13	SHOC2	P17252	PRKCA	S85	A88T	88	Missense	distal	3	no	17.159	16.920	EPSD	TCGA;ICGC;COSMIC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	Q9UQ13	SHOC2	P17252	PRKCA	S85	G80E	80	Missense	distal	-5	no	17.159	17.142	EPSD	TCGA;ICGC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	Q9UQ13	SHOC2	P17252	PRKCA	S102	E99K	99	Missense	distal	-3	no	15.368	18.280	EPSD	TCGA;ICGC;COSMIC	16.704	Gain
AGC_PKC_PKCa_PRKCA_ST	Q9UQ13	SHOC2	P17252	PRKCA	S297	R301T	301	Missense	distal	4	no	17.386	16.709	PhosphoSitePlus;EPSD	TCGA;COSMIC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	P29350	PTPN6	P17252	PRKCA	S10	S10N	10	Missense	central	0	yes	18.049	0.000	EPSD	TCGA;COSMIC	16.704	Loss
AGC_PKC_PKCa_PRKCA_ST	P29350	PTPN6	P17252	PRKCA	S32	R30Q	30	Missense	proximal	-2	no	20.658	18.899	EPSD	TCGA;COSMIC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	P29350	PTPN6	P17252	PRKCA	S42	S40L	40	Missense	proximal	-2	no	17.466	18.080	EPSD	TCGA;COSMIC	16.704	Up-regulation
AGC_PKC_PKCa_PRKCA_ST	P29350	PTPN6	P17252	PRKCA	S42	Q48E	48	Missense	distal	6	no	17.466	17.483	EPSD	TCGA;COSMIC	16.704	Up-regulation
AGC_PKC_PKCa_PRKCA_ST	P29350	PTPN6	P17252	PRKCA	S42	S42F	42	Missense	central	0	yes	17.466	0.000	EPSD	TCGA;COSMIC;GDSC;CCLE	16.704	Loss
AGC_PKC_PKCa_PRKCA_ST	P29350	PTPN6	P17252	PRKCA	S42	R44K	44	Missense	proximal	2	no	17.466	17.045	EPSD	TCGA;COSMIC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	P29350	PTPN6	P17252	PRKCA	S556	E561Q	561	Missense	distal	5	no	21.149	21.410	EPSD	TCGA;ICGC;COSMIC	16.704	Up-regulation
AGC_PKC_PKCa_PRKCA_ST	P29350	PTPN6	P17252	PRKCA	S556	S556L	556	Missense	central	0	yes	21.149	0.000	EPSD	TCGA	16.704	Loss
AGC_PKC_PKCa_PRKCA_ST	P29350	PTPN6	P17252	PRKCA	S556	S553P	553	Missense	distal	-3	no	21.149	20.170	EPSD	TCGA;COSMIC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	P29350	PTPN6	P17252	PRKCA	S557	E561Q	561	Missense	distal	4	no	18.262	18.412	EPSD	TCGA;ICGC;COSMIC	16.704	Up-regulation
AGC_PKC_PKCa_PRKCA_ST	P29350	PTPN6	P17252	PRKCA	S557	S556L	556	Missense	proximal	-1	no	18.262	17.842	EPSD	TCGA	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	P29350	PTPN6	P17252	PRKCA	S557	S553P	553	Missense	distal	-4	no	18.262	18.090	EPSD	TCGA;COSMIC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	O60674	JAK2	P17252	PRKCA	S358	S364C	364	Missense	distal	6	no	18.222	18.055	EPSD	TCGA;ICGC;COSMIC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	P42261	GRIA1	P17252	PRKCA	S306	A301V	301	Missense	distal	-5	no	19.207	19.123	EPSD	TCGA;COSMIC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	Q14994	NR1I3	P17252	PRKCA	T38	K32T	32	Missense	distal	-6	no	18.555	18.363	PhosphoSitePlus	TCGA	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	Q14994	NR1I3	P17252	PRKCA	T38	S42R	42	Missense	distal	4	no	18.555	18.801	PhosphoSitePlus	TCGA;COSMIC	16.704	Up-regulation
AGC_PKC_PKCa_PRKCA_ST	Q14994	NR1I3	P17252	PRKCA	T38	S40C	40	Missense	proximal	2	no	18.555	18.824	PhosphoSitePlus	TCGA;COSMIC	16.704	Up-regulation
AGC_PKC_PKCa_PRKCA_ST	Q14994	NR1I3	P17252	PRKCA	T38	C31F	31	Missense	distal	-7	no	18.555	18.561	PhosphoSitePlus	TCGA;ICGC;COSMIC	16.704	Up-regulation
AGC_PKC_PKCa_PRKCA_ST	Q14994	NR1I3	P17252	PRKCA	T38	K32N	32	Missense	distal	-6	no	18.555	18.431	PhosphoSitePlus	TCGA;ICGC;COSMIC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	Q14994	NR1I3	P17252	PRKCA	T38	R37I	37	Missense	proximal	-1	no	18.555	16.884	PhosphoSitePlus	TCGA;COSMIC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	P35869	AHR	P17252	PRKCA	S36	R38W	38	Missense	proximal	2	no	21.241	15.802	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC;CCLE	16.704	Loss
AGC_PKC_PKCa_PRKCA_ST	P35869	AHR	P17252	PRKCA	S36	L43P	43	Missense	distal	7	no	21.241	21.275	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	16.704	Up-regulation
AGC_PKC_PKCa_PRKCA_ST	P35869	AHR	P17252	PRKCA	S36	R40T	40	Missense	distal	4	no	21.241	20.564	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	P35869	AHR	P17252	PRKCA	S36	R38P	38	Missense	proximal	2	no	21.241	16.039	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	16.704	Loss
AGC_PKC_PKCa_PRKCA_ST	P35869	AHR	P17252	PRKCA	S36	P35L	35	Missense	proximal	-1	no	21.241	21.122	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	P35869	AHR	P17252	PRKCA	S81	V74I	74	Missense	distal	-7	no	18.258	18.257	EPSD	TCGA;ICGC;COSMIC;CCLE	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	P35869	AHR	P17252	PRKCA	S81	S81C	81	Missense	central	0	yes	18.258	0.000	EPSD	TCGA;ICGC;COSMIC	16.704	Loss
AGC_PKC_PKCa_PRKCA_ST	P35869	AHR	P17252	PRKCA	T92	G96R	96	Missense	distal	4	no	16.571	17.174	EPSD	TCGA;ICGC;COSMIC	16.704	Gain
AGC_PKC_PKCa_PRKCA_ST	P35869	AHR	P17252	PRKCA	S723	E725K	725	Missense	proximal	2	no	13.694	18.973	EPSD	TCGA;ICGC;COSMIC	16.704	Gain
AGC_PKC_PKCa_PRKCA_ST	P35611	ADD1	P17252	PRKCA	S59	P65H	65	Missense	distal	6	no	16.841	16.802	EPSD	TCGA;ICGC;COSMIC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	P35611	ADD1	P17252	PRKCA	S353	R354C	354	Missense	proximal	1	no	16.821	13.985	EPSD	TCGA;ICGC;COSMIC	16.704	Loss
AGC_PKC_PKCa_PRKCA_ST	P35611	ADD1	P17252	PRKCA	S358	R354C	354	Missense	distal	-4	no	17.039	15.696	EPSD	TCGA;ICGC;COSMIC	16.704	Loss
AGC_PKC_PKCa_PRKCA_ST	P35611	ADD1	P17252	PRKCA	S436	R442W	442	Missense	distal	6	no	18.846	18.598	EPSD	TCGA;ICGC;COSMIC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	P35611	ADD1	P17252	PRKCA	S436	Q438H	438	Missense	proximal	2	no	18.846	17.657	EPSD	TCGA;ICGC;COSMIC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	P35611	ADD1	P17252	PRKCA	S436	Q438R	438	Missense	proximal	2	no	18.846	22.680	EPSD	TCGA;ICGC;COSMIC	16.704	Up-regulation
AGC_PKC_PKCa_PRKCA_ST	P35611	ADD1	P17252	PRKCA	S450	L448P	448	Missense	proximal	-2	no	20.964	20.610	EPSD	TCGA;ICGC;COSMIC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	P35611	ADD1	P17252	PRKCA	S465	T470A	470	Missense	distal	5	no	16.540	16.819	EPSD	TCGA;ICGC;COSMIC	16.704	Gain
AGC_PKC_PKCa_PRKCA_ST	P49802	RGS7	P17252	PRKCA	S218	M220L	220	Missense	proximal	2	no	18.906	18.367	EPSD	TCGA;COSMIC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	P49802	RGS7	P17252	PRKCA	S218	R219S	219	Missense	proximal	1	no	18.906	17.732	EPSD	TCGA;COSMIC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	P49802	RGS7	P17252	PRKCA	S218	H224N	224	Missense	distal	6	no	18.906	18.809	EPSD	TCGA;COSMIC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	P49802	RGS7	P17252	PRKCA	S218	K225T	225	Missense	distal	7	no	18.906	18.816	EPSD	TCGA;COSMIC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	P49802	RGS7	P17252	PRKCA	S229	S229Y	229	Missense	central	0	yes	17.673	0.000	EPSD	TCGA;COSMIC	16.704	Loss
AGC_PKC_PKCa_PRKCA_ST	P49802	RGS7	P17252	PRKCA	S229	R227L	227	Missense	proximal	-2	no	17.673	14.985	EPSD	TCGA;COSMIC	16.704	Loss
AGC_PKC_PKCa_PRKCA_ST	P49802	RGS7	P17252	PRKCA	S229	D236N	236	Missense	distal	7	no	17.673	17.646	EPSD	TCGA;COSMIC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	P49802	RGS7	P17252	PRKCA	S229	G232S	232	Missense	distal	3	no	17.673	16.921	EPSD	TCGA;COSMIC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	P49802	RGS7	P17252	PRKCA	S229	K225T	225	Missense	distal	-4	no	17.673	16.783	EPSD	TCGA;COSMIC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	P49802	RGS7	P17252	PRKCA	S229	K228T	228	Missense	proximal	-1	no	17.673	16.850	EPSD	TCGA	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	P49802	RGS7	P17252	PRKCA	S285	T287R	287	Missense	proximal	2	no	13.612	18.422	EPSD	TCGA;COSMIC	16.704	Gain
AGC_PKC_PKCa_PRKCA_ST	P49802	RGS7	P17252	PRKCA	S323	S323R	323	Missense	central	0	yes	17.009	0.000	EPSD	TCGA;COSMIC	16.704	Loss
AGC_PKC_PKCa_PRKCA_ST	P49802	RGS7	P17252	PRKCA	S323	W330C	330	Missense	distal	7	no	17.009	16.966	EPSD	TCGA;COSMIC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	P49802	RGS7	P17252	PRKCA	S323	A318E	318	Missense	distal	-5	no	17.009	17.182	EPSD	TCGA;COSMIC	16.704	Up-regulation
AGC_PKC_PKCa_PRKCA_ST	P49802	RGS7	P17252	PRKCA	S323	E317K	317	Missense	distal	-6	no	17.009	17.077	EPSD	TCGA;COSMIC	16.704	Up-regulation
AGC_PKC_PKCa_PRKCA_ST	P49802	RGS7	P17252	PRKCA	S323	E321D	321	Missense	proximal	-2	no	17.009	17.717	EPSD	TCGA;COSMIC	16.704	Up-regulation
AGC_PKC_PKCa_PRKCA_ST	P49802	RGS7	P17252	PRKCA	S323	S319I	319	Missense	distal	-4	no	17.009	16.567	EPSD	TCGA;COSMIC	16.704	Loss
AGC_PKC_PKCa_PRKCA_ST	P49802	RGS7	P17252	PRKCA	S434	D433N	433	Missense	proximal	-1	no	16.377	16.715	PhosphoSitePlus	TCGA;COSMIC	16.704	Gain
AGC_PKC_PKCa_PRKCA_ST	P49802	RGS7	P17252	PRKCA	S463	F467C	467	Missense	distal	4	no	20.138	19.344	EPSD	TCGA;ICGC;COSMIC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	P49802	RGS7	P17252	PRKCA	S463	S463C	463	Missense	central	0	yes	20.138	0.000	EPSD	TCGA;ICGC;COSMIC	16.704	Loss
AGC_PKC_PKCa_PRKCA_ST	P49802	RGS7	P17252	PRKCA	S463	D459N	459	Missense	distal	-4	no	20.138	20.486	EPSD	TCGA;ICGC;COSMIC	16.704	Up-regulation
AGC_PKC_PKCa_PRKCA_ST	P49802	RGS7	P17252	PRKCA	S463	R460C	460	Missense	distal	-3	no	20.138	17.398	EPSD	TCGA;ICGC;COSMIC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	P49802	RGS7	P17252	PRKCA	S463	E465D	465	Missense	proximal	2	no	20.138	20.560	EPSD	TCGA;ICGC	16.704	Up-regulation
AGC_PKC_PKCa_PRKCA_ST	Q92681	RSC1A1	P17252	PRKCA	S66	S73Y	73	Missense	distal	7	no	17.835	17.829	EPSD	TCGA;ICGC;COSMIC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	Q92681	RSC1A1	P17252	PRKCA	S66	K68N	68	Missense	proximal	2	no	17.835	12.886	EPSD	TCGA;ICGC;COSMIC	16.704	Loss
AGC_PKC_PKCa_PRKCA_ST	P81274	GPSM2	P17252	PRKCA	S7	M8I	8	Missense	proximal	1	no	19.604	20.655	EPSD	TCGA;ICGC;COSMIC	16.704	Up-regulation
AGC_PKC_PKCa_PRKCA_ST	P81274	GPSM2	P17252	PRKCA	S7	E3D	3	Missense	distal	-4	no	19.604	19.428	EPSD	TCGA;ICGC;COSMIC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	P81274	GPSM2	P17252	PRKCA	S478	I482V	482	Missense	distal	4	no	17.087	17.209	EPSD	TCGA;ICGC;COSMIC	16.704	Up-regulation
AGC_PKC_PKCa_PRKCA_ST	P81274	GPSM2	P17252	PRKCA	S556	R558S	558	Missense	proximal	2	no	18.532	13.912	EPSD	TCGA;ICGC;COSMIC	16.704	Loss
AGC_PKC_PKCa_PRKCA_ST	P81274	GPSM2	P17252	PRKCA	S565	R558S	558	Missense	distal	-7	no	18.244	18.239	EPSD	TCGA;ICGC;COSMIC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	P81274	GPSM2	P17252	PRKCA	S677	S677A	677	Missense	central	0	yes	18.308	0.000	EPSD	TCGA;ICGC	16.704	Loss
AGC_PKC_PKCa_PRKCA_ST	P11309	PIM1	P17252	PRKCA	S24	A22V	22	Missense	proximal	-2	no	18.597	18.841	EPSD	TCGA;ICGC;COSMIC	16.704	Up-regulation
AGC_PKC_PKCa_PRKCA_ST	P11309	PIM1	P17252	PRKCA	S28	A22V	22	Missense	distal	-6	no	25.045	24.968	EPSD	TCGA;ICGC;COSMIC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	Q9NS23	RASSF1	P17252	PRKCA	S182	V175M	175	Missense	distal	-7	no	19.774	19.784	EPSD	TCGA;COSMIC	16.704	Up-regulation
AGC_PKC_PKCa_PRKCA_ST	Q9NS23	RASSF1	P17252	PRKCA	S188	R194W	194	Missense	distal	6	no	17.758	17.510	EPSD	TCGA	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	Q9NS23	RASSF1	P17252	PRKCA	S201	R205C	205	Missense	distal	4	no	24.182	22.780	EPSD	TCGA;COSMIC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	Q9NS23	RASSF1	P17252	PRKCA	S201	V202A	202	Missense	proximal	1	no	24.182	24.028	EPSD	TCGA;COSMIC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	Q9NS23	RASSF1	P17252	PRKCA	S201	R194W	194	Missense	distal	-7	no	24.182	24.165	EPSD	TCGA	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	Q9NS23	RASSF1	P17252	PRKCA	T206	R205C	205	Missense	proximal	-1	no	17.444	14.784	EPSD	TCGA;COSMIC	16.704	Loss
AGC_PKC_PKCa_PRKCA_ST	Q9NS23	RASSF1	P17252	PRKCA	T206	V202A	202	Missense	distal	-4	no	17.444	18.003	EPSD	TCGA;COSMIC	16.704	Up-regulation
AGC_PKC_PKCa_PRKCA_ST	Q9NS23	RASSF1	P17252	PRKCA	S207	R205C	205	Missense	proximal	-2	no	21.710	20.010	EPSD	TCGA;COSMIC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	Q9NS23	RASSF1	P17252	PRKCA	S207	V202A	202	Missense	distal	-5	no	21.710	21.794	EPSD	TCGA;COSMIC	16.704	Up-regulation
AGC_PKC_PKCa_PRKCA_ST	P35503	UGT1A3	P17252	PRKCA	S43	E46Q	46	Missense	distal	3	no	18.448	17.233	PhosphoSitePlus	TCGA;ICGC;COSMIC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	P35503	UGT1A3	P17252	PRKCA	S43	E46D	46	Missense	distal	3	no	18.448	17.961	PhosphoSitePlus	TCGA;ICGC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	Q99801	NKX3-1	P17252	PRKCA	S48	D53H	53	Missense	distal	5	no	22.062	22.164	PhosphoSitePlus	TCGA;ICGC;COSMIC	16.704	Up-regulation
AGC_PKC_PKCa_PRKCA_ST	Q13224	GRIN2B	P17252	PRKCA	S383	S383P	383	Missense	central	0	yes	17.582	0.000	EPSD	TCGA;ICGC;COSMIC	16.704	Loss
AGC_PKC_PKCa_PRKCA_ST	Q13224	GRIN2B	P17252	PRKCA	S383	M386I	386	Missense	distal	3	no	17.582	16.301	EPSD	TCGA;ICGC;COSMIC	16.704	Loss
AGC_PKC_PKCa_PRKCA_ST	Q13224	GRIN2B	P17252	PRKCA	S383	Y388C	388	Missense	distal	5	no	17.582	16.965	EPSD	TCGA;ICGC;COSMIC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	Q13224	GRIN2B	P17252	PRKCA	S770	G771V	771	Missense	proximal	1	no	16.290	17.021	EPSD	TCGA;ICGC;COSMIC	16.704	Gain
AGC_PKC_PKCa_PRKCA_ST	Q13224	GRIN2B	P17252	PRKCA	S930	E928K	928	Missense	proximal	-2	no	14.730	17.229	EPSD	TCGA;ICGC;COSMIC	16.704	Gain
AGC_PKC_PKCa_PRKCA_ST	Q13224	GRIN2B	P17252	PRKCA	S1043	D1037N	1037	Missense	distal	-6	no	19.592	19.619	EPSD	TCGA;ICGC;COSMIC	16.704	Up-regulation
AGC_PKC_PKCa_PRKCA_ST	Q13224	GRIN2B	P17252	PRKCA	S1043	K1045N	1045	Missense	proximal	2	no	19.592	14.643	EPSD	TCGA;ICGC;COSMIC	16.704	Loss
AGC_PKC_PKCa_PRKCA_ST	Q13224	GRIN2B	P17252	PRKCA	S1166	R1164C	1164	Missense	proximal	-2	no	19.183	17.483	EPSD	TCGA;ICGC;COSMIC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	Q13224	GRIN2B	P17252	PRKCA	S1166	G1170R	1170	Missense	distal	4	no	19.183	19.786	EPSD	TCGA;ICGC;COSMIC	16.704	Up-regulation
AGC_PKC_PKCa_PRKCA_ST	Q13224	GRIN2B	P17252	PRKCA	S1166	S1168R	1168	Missense	proximal	2	no	19.183	23.802	EPSD	TCGA;ICGC;COSMIC	16.704	Up-regulation
AGC_PKC_PKCa_PRKCA_ST	Q13224	GRIN2B	P17252	PRKCA	S1166	G1169R	1169	Missense	distal	3	no	19.183	19.822	EPSD	TCGA;ICGC;COSMIC;CCLE	16.704	Up-regulation
AGC_PKC_PKCa_PRKCA_ST	Q13224	GRIN2B	P17252	PRKCA	S1166	G1170E	1170	Missense	distal	4	no	19.183	19.418	EPSD	TCGA;ICGC;COSMIC	16.704	Up-regulation
AGC_PKC_PKCa_PRKCA_ST	Q13224	GRIN2B	P17252	PRKCA	S1166	D1161N	1161	Missense	distal	-5	no	19.183	19.212	EPSD	TCGA;ICGC;COSMIC	16.704	Up-regulation
AGC_PKC_PKCa_PRKCA_ST	Q13224	GRIN2B	P17252	PRKCA	S1303	R1299H	1299	Missense	distal	-4	no	18.841	18.267	EPSD	TCGA;ICGC;COSMIC;CCLE	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	Q13224	GRIN2B	P17252	PRKCA	S1303	R1300Q	1300	Missense	distal	-3	no	18.841	15.984	EPSD	TCGA;ICGC;COSMIC	16.704	Loss
AGC_PKC_PKCa_PRKCA_ST	Q13224	GRIN2B	P17252	PRKCA	S1303	R1299C	1299	Missense	distal	-4	no	18.841	17.498	EPSD	TCGA;ICGC;COSMIC;GDSC;CCLE	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	Q13224	GRIN2B	P17252	PRKCA	S1303	N1296T	1296	Missense	distal	-7	no	18.841	18.843	EPSD	TCGA;ICGC	16.704	Up-regulation
AGC_PKC_PKCa_PRKCA_ST	Q13224	GRIN2B	P17252	PRKCA	S1323	A1318G	1318	Missense	distal	-5	no	21.123	21.313	PhosphoSitePlus	TCGA;ICGC;COSMIC	16.704	Up-regulation
AGC_PKC_PKCa_PRKCA_ST	Q13224	GRIN2B	P17252	PRKCA	S1323	R1320H	1320	Missense	distal	-3	no	21.123	17.267	PhosphoSitePlus	TCGA;ICGC;COSMIC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	Q13224	GRIN2B	P17252	PRKCA	T1410	S1415L	1415	Missense	distal	5	no	18.718	18.528	EPSD	TCGA;ICGC;COSMIC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	Q13224	GRIN2B	P17252	PRKCA	T1410	T1410P	1410	Missense	central	0	yes	18.718	0.000	EPSD	TCGA;ICGC;COSMIC	16.704	Loss
AGC_PKC_PKCa_PRKCA_ST	Q13224	GRIN2B	P17252	PRKCA	T1410	S1403F	1403	Missense	distal	-7	no	18.718	18.710	EPSD	TCGA;ICGC;COSMIC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	Q13224	GRIN2B	P17252	PRKCA	T1410	A1417T	1417	Missense	distal	7	no	18.718	18.727	EPSD	TCGA;ICGC;COSMIC;GDSC;CCLE	16.704	Up-regulation
AGC_PKC_PKCa_PRKCA_ST	Q13224	GRIN2B	P17252	PRKCA	T1410	V1411M	1411	Missense	proximal	1	no	18.718	18.379	EPSD	TCGA;ICGC;COSMIC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	Q96MS0	ROBO3	P17252	PRKCA	S404	R406I	406	Missense	proximal	2	no	19.215	14.183	EPSD	TCGA;ICGC;COSMIC	16.704	Loss
AGC_PKC_PKCa_PRKCA_ST	Q96MS0	ROBO3	P17252	PRKCA	S404	R400H	400	Missense	distal	-4	no	19.215	18.641	EPSD	TCGA;ICGC;COSMIC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	Q96MS0	ROBO3	P17252	PRKCA	S404	P405S	405	Missense	proximal	1	no	19.215	18.816	EPSD	TCGA;ICGC;COSMIC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	Q96MS0	ROBO3	P17252	PRKCA	S725	S725N	725	Missense	central	0	yes	17.882	0.000	EPSD	TCGA;ICGC;COSMIC	16.704	Loss
AGC_PKC_PKCa_PRKCA_ST	Q96MS0	ROBO3	P17252	PRKCA	S725	R732K	732	Missense	distal	7	no	17.882	17.932	EPSD	TCGA;ICGC;COSMIC	16.704	Up-regulation
AGC_PKC_PKCa_PRKCA_ST	Q96MS0	ROBO3	P17252	PRKCA	T729	S725N	725	Missense	distal	-4	no	16.765	16.435	EPSD	TCGA;ICGC;COSMIC	16.704	Loss
AGC_PKC_PKCa_PRKCA_ST	Q96MS0	ROBO3	P17252	PRKCA	T729	L734H	734	Missense	distal	5	no	16.765	16.838	EPSD	TCGA;ICGC;COSMIC	16.704	Up-regulation
AGC_PKC_PKCa_PRKCA_ST	Q96MS0	ROBO3	P17252	PRKCA	T729	R732K	732	Missense	distal	3	no	16.765	16.142	EPSD	TCGA;ICGC;COSMIC	16.704	Loss
AGC_PKC_PKCa_PRKCA_ST	Q96MS0	ROBO3	P17252	PRKCA	S1293	R1298H	1298	Missense	distal	5	no	16.763	16.504	EPSD	TCGA;ICGC	16.704	Loss
AGC_PKC_PKCa_PRKCA_ST	Q96MS0	ROBO3	P17252	PRKCA	S1330	R1334L	1334	Missense	distal	4	no	17.744	16.706	PhosphoSitePlus	TCGA;ICGC;COSMIC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	Q96MS0	ROBO3	P17252	PRKCA	S1330	Y1326N	1326	Missense	distal	-4	no	17.744	17.608	PhosphoSitePlus	TCGA;ICGC;COSMIC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	Q96MS0	ROBO3	P17252	PRKCA	S1374	R1371Q	1371	Missense	distal	-3	no	20.755	17.897	EPSD	TCGA;ICGC;COSMIC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	P06127	CD5	P17252	PRKCA	S42	S42W	42	Missense	central	0	yes	17.565	0.000	EPSD	TCGA;ICGC;COSMIC	16.704	Loss
AGC_PKC_PKCa_PRKCA_ST	P06127	CD5	P17252	PRKCA	S42	C44G	44	Missense	proximal	2	no	17.565	16.670	EPSD	TCGA;ICGC;COSMIC	16.704	Loss
AGC_PKC_PKCa_PRKCA_ST	P06127	CD5	P17252	PRKCA	S42	S42L	42	Missense	central	0	yes	17.565	0.000	EPSD	TCGA;ICGC;COSMIC	16.704	Loss
AGC_PKC_PKCa_PRKCA_ST	P06127	CD5	P17252	PRKCA	S42	K43T	43	Missense	proximal	1	no	17.565	16.681	EPSD	TCGA;ICGC;COSMIC	16.704	Loss
AGC_PKC_PKCa_PRKCA_ST	P06127	CD5	P17252	PRKCA	S42	Q47K	47	Missense	distal	5	no	17.565	17.717	EPSD	TCGA;ICGC;COSMIC	16.704	Up-regulation
AGC_PKC_PKCa_PRKCA_ST	P06127	CD5	P17252	PRKCA	S42	E49D	49	Missense	distal	7	no	17.565	17.617	EPSD	TCGA;ICGC	16.704	Up-regulation
AGC_PKC_PKCa_PRKCA_ST	P06127	CD5	P17252	PRKCA	T142	T139R	139	Missense	distal	-3	no	17.394	21.557	EPSD	TCGA;ICGC;COSMIC	16.704	Up-regulation
AGC_PKC_PKCa_PRKCA_ST	P06127	CD5	P17252	PRKCA	S309	V315E	315	Missense	distal	6	no	19.187	19.242	EPSD	TCGA;ICGC;COSMIC	16.704	Up-regulation
AGC_PKC_PKCa_PRKCA_ST	P06127	CD5	P17252	PRKCA	S309	E313K	313	Missense	distal	4	no	19.187	19.726	EPSD	TCGA;ICGC;COSMIC	16.704	Up-regulation
AGC_PKC_PKCa_PRKCA_ST	P06127	CD5	P17252	PRKCA	S309	W312L	312	Missense	distal	3	no	19.187	19.883	EPSD	TCGA;ICGC	16.704	Up-regulation
AGC_PKC_PKCa_PRKCA_ST	P06127	CD5	P17252	PRKCA	T436	N443S	443	Missense	distal	7	no	16.941	16.965	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	16.704	Up-regulation
AGC_PKC_PKCa_PRKCA_ST	P06127	CD5	P17252	PRKCA	T436	F429L	429	Missense	distal	-7	no	16.941	16.944	EPSD;PhosphoSitePlus	TCGA;ICGC	16.704	Up-regulation
AGC_PKC_PKCa_PRKCA_ST	P06127	CD5	P17252	PRKCA	T436	R438Q	438	Missense	proximal	2	no	16.941	13.107	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	16.704	Loss
AGC_PKC_PKCa_PRKCA_ST	P06239	LCK	P17252	PRKCA	S42	T35M	35	Missense	distal	-7	no	18.146	18.152	PhosphoSitePlus	TCGA;ICGC;COSMIC	16.704	Up-regulation
AGC_PKC_PKCa_PRKCA_ST	P06239	LCK	P17252	PRKCA	S42	V44L	44	Missense	proximal	2	no	18.146	18.174	PhosphoSitePlus	TCGA;ICGC;COSMIC	16.704	Up-regulation
AGC_PKC_PKCa_PRKCA_ST	P06239	LCK	P17252	PRKCA	S42	R39Q	39	Missense	distal	-3	no	18.146	15.289	PhosphoSitePlus	TCGA;ICGC;COSMIC	16.704	Loss
AGC_PKC_PKCa_PRKCA_ST	P06239	LCK	P17252	PRKCA	S42	R45W	45	Missense	distal	3	no	18.146	15.213	PhosphoSitePlus	TCGA;ICGC;COSMIC;GDSC;CCLE	16.704	Loss
AGC_PKC_PKCa_PRKCA_ST	P06239	LCK	P17252	PRKCA	T50	E52K	52	Missense	proximal	2	no	11.719	16.998	EPSD	TCGA;ICGC;COSMIC	16.704	Gain
AGC_PKC_PKCa_PRKCA_ST	P06239	LCK	P17252	PRKCA	S133	R134H	134	Missense	proximal	1	no	18.873	18.060	EPSD	TCGA;COSMIC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	P06239	LCK	P17252	PRKCA	S156	E157K	157	Missense	proximal	1	no	15.476	17.080	EPSD	TCGA;COSMIC	16.704	Gain
AGC_PKC_PKCa_PRKCA_ST	P06239	LCK	P17252	PRKCA	S274	Q277K	277	Missense	distal	3	no	17.165	18.996	EPSD	TCGA;COSMIC	16.704	Up-regulation
AGC_PKC_PKCa_PRKCA_ST	P06239	LCK	P17252	PRKCA	S274	S274N	274	Missense	central	0	yes	17.165	0.000	EPSD	TCGA;COSMIC	16.704	Loss
AGC_PKC_PKCa_PRKCA_ST	P06239	LCK	P17252	PRKCA	S274	S281F	281	Missense	distal	7	no	17.165	17.102	EPSD	TCGA;COSMIC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	P06239	LCK	P17252	PRKCA	T395	E393K	393	Missense	proximal	-2	no	14.245	16.744	EPSD	TCGA;COSMIC	16.704	Gain
AGC_PKC_PKCa_PRKCA_ST	P32004	L1CAM	P17252	PRKCA	T527	G532C	532	Missense	distal	5	no	16.781	16.331	EPSD	TCGA;COSMIC	16.704	Loss
AGC_PKC_PKCa_PRKCA_ST	P32004	L1CAM	P17252	PRKCA	T527	R525S	525	Missense	proximal	-2	no	16.781	13.479	EPSD	TCGA;COSMIC	16.704	Loss
AGC_PKC_PKCa_PRKCA_ST	P32004	L1CAM	P17252	PRKCA	T527	S533F	533	Missense	distal	6	no	16.781	16.740	EPSD	TCGA;COSMIC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	P32004	L1CAM	P17252	PRKCA	T527	Q522H	522	Missense	distal	-5	no	16.781	16.578	EPSD	TCGA;COSMIC	16.704	Loss
AGC_PKC_PKCa_PRKCA_ST	P32004	L1CAM	P17252	PRKCA	T527	E529K	529	Missense	proximal	2	no	16.781	22.060	EPSD	TCGA;COSMIC	16.704	Up-regulation
AGC_PKC_PKCa_PRKCA_ST	P32004	L1CAM	P17252	PRKCA	T527	S526I	526	Missense	proximal	-1	no	16.781	15.498	EPSD	TCGA	16.704	Loss
AGC_PKC_PKCa_PRKCA_ST	P32004	L1CAM	P17252	PRKCA	T527	S533Y	533	Missense	distal	6	no	16.781	16.800	EPSD	TCGA	16.704	Up-regulation
AGC_PKC_PKCa_PRKCA_ST	P32004	L1CAM	P17252	PRKCA	S1146	R1145C	1145	Missense	proximal	-1	no	17.681	15.021	EPSD	TCGA;COSMIC	16.704	Loss
AGC_PKC_PKCa_PRKCA_ST	P32004	L1CAM	P17252	PRKCA	S1146	C1141F	1141	Missense	distal	-5	no	17.681	18.033	EPSD	TCGA;COSMIC	16.704	Up-regulation
AGC_PKC_PKCa_PRKCA_ST	P32004	L1CAM	P17252	PRKCA	S1146	V1153L	1153	Missense	distal	7	no	17.681	17.740	EPSD	TCGA	16.704	Up-regulation
AGC_PKC_PKCa_PRKCA_ST	P32004	L1CAM	P17252	PRKCA	S1152	R1145C	1145	Missense	distal	-7	no	20.622	20.603	EPSD	TCGA;COSMIC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	P32004	L1CAM	P17252	PRKCA	S1152	K1154T	1154	Missense	proximal	2	no	20.622	16.233	EPSD	TCGA;COSMIC	16.704	Loss
AGC_PKC_PKCa_PRKCA_ST	P32004	L1CAM	P17252	PRKCA	S1152	V1153L	1153	Missense	proximal	1	no	20.622	20.497	EPSD	TCGA	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	P32004	L1CAM	P17252	PRKCA	S1194	G1197E	1197	Missense	distal	3	no	16.835	16.237	EPSD	TCGA;COSMIC	16.704	Loss
AGC_PKC_PKCa_PRKCA_ST	P32004	L1CAM	P17252	PRKCA	S1194	G1197V	1197	Missense	distal	3	no	16.835	15.621	EPSD	TCGA;COSMIC	16.704	Loss
AGC_PKC_PKCa_PRKCA_ST	P32004	L1CAM	P17252	PRKCA	S1194	D1198Y	1198	Missense	distal	4	no	16.835	16.790	EPSD	TCGA	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	P32004	L1CAM	P17252	PRKCA	S1230	E1236K	1236	Missense	distal	6	no	19.747	19.841	EPSD	TCGA;COSMIC	16.704	Up-regulation
AGC_PKC_PKCa_PRKCA_ST	P32004	L1CAM	P17252	PRKCA	S1230	S1224L	1224	Missense	distal	-6	no	19.747	19.681	EPSD	TCGA;COSMIC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	Q01959	SLC6A3	P17252	PRKCA	S2	S4I	4	Missense	proximal	2	no	18.203	17.791	EPSD	TCGA;ICGC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	Q01959	SLC6A3	P17252	PRKCA	S262	V259L	259	Missense	distal	-3	no	17.762	17.097	EPSD	TCGA;ICGC;COSMIC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	Q01959	SLC6A3	P17252	PRKCA	S262	G258C	258	Missense	distal	-4	no	17.762	16.521	EPSD	TCGA;ICGC;COSMIC	16.704	Loss
AGC_PKC_PKCa_PRKCA_ST	Q01959	SLC6A3	P17252	PRKCA	S262	V259M	259	Missense	distal	-3	no	17.762	18.480	EPSD	TCGA;ICGC;COSMIC	16.704	Up-regulation
AGC_PKC_PKCa_PRKCA_ST	Q01959	SLC6A3	P17252	PRKCA	S262	K257N	257	Missense	distal	-5	no	17.762	17.420	EPSD	TCGA;ICGC;COSMIC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	O15350	TP73	P17252	PRKCA	S289	R293C	293	Missense	distal	4	no	19.811	18.410	EPSD	TCGA;ICGC;COSMIC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	O15350	TP73	P17252	PRKCA	S289	A296T	296	Missense	distal	7	no	19.811	19.820	EPSD	TCGA;ICGC;COSMIC	16.704	Up-regulation
AGC_PKC_PKCa_PRKCA_ST	O15350	TP73	P17252	PRKCA	S289	S289F	289	Missense	central	0	yes	19.811	0.000	EPSD	TCGA;ICGC;COSMIC	16.704	Loss
AGC_PKC_PKCa_PRKCA_ST	O15350	TP73	P17252	PRKCA	S289	R293S	293	Missense	distal	4	no	19.811	19.565	EPSD	TCGA;ICGC;COSMIC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	O15350	TP73	P17252	PRKCA	S326	A324V	324	Missense	proximal	-2	no	19.187	19.431	EPSD	TCGA;ICGC;COSMIC	16.704	Up-regulation
AGC_PKC_PKCa_PRKCA_ST	O15350	TP73	P17252	PRKCA	S388	Q391R	391	Missense	distal	3	no	16.284	18.737	PhosphoSitePlus	TCGA;ICGC;COSMIC;CCLE	16.704	Gain
AGC_PKC_PKCa_PRKCA_ST	O15350	TP73	P17252	PRKCA	S471	A472T	472	Missense	proximal	1	no	17.254	16.783	EPSD	TCGA;COSMIC;GDSC;CCLE	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	P28329	CHAT	P17252	PRKCA	S125	S126R	126	Missense	proximal	1	no	15.659	16.833	EPSD	TCGA;COSMIC	16.704	Gain
AGC_PKC_PKCa_PRKCA_ST	P28329	CHAT	P17252	PRKCA	S464	H460L	460	Missense	distal	-4	no	18.756	18.706	EPSD	TCGA;COSMIC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	P28329	CHAT	P17252	PRKCA	S464	L457M	457	Missense	distal	-7	no	18.756	18.764	EPSD	TCGA;COSMIC	16.704	Up-regulation
AGC_PKC_PKCa_PRKCA_ST	P28329	CHAT	P17252	PRKCA	S464	R470Q	470	Missense	distal	6	no	18.756	18.633	EPSD	TCGA;COSMIC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	P28329	CHAT	P17252	PRKCA	S464	R466K	466	Missense	proximal	2	no	18.756	18.334	EPSD	TCGA;COSMIC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	P28329	CHAT	P17252	PRKCA	S465	H460L	460	Missense	distal	-5	no	18.460	18.688	EPSD	TCGA;COSMIC	16.704	Up-regulation
AGC_PKC_PKCa_PRKCA_ST	P28329	CHAT	P17252	PRKCA	S465	R470Q	470	Missense	distal	5	no	18.460	18.452	EPSD	TCGA;COSMIC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	P28329	CHAT	P17252	PRKCA	S465	R466K	466	Missense	proximal	1	no	18.460	18.498	EPSD	TCGA;COSMIC	16.704	Up-regulation
AGC_PKC_PKCa_PRKCA_ST	P28329	CHAT	P17252	PRKCA	S473	V474I	474	Missense	proximal	1	no	18.312	19.023	EPSD	TCGA;COSMIC;CCLE	16.704	Up-regulation
AGC_PKC_PKCa_PRKCA_ST	P28329	CHAT	P17252	PRKCA	S473	S473Y	473	Missense	central	0	yes	18.312	0.000	EPSD	TCGA;COSMIC	16.704	Loss
AGC_PKC_PKCa_PRKCA_ST	P28329	CHAT	P17252	PRKCA	S473	P478R	478	Missense	distal	5	no	18.312	18.294	EPSD	TCGA;COSMIC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	P28329	CHAT	P17252	PRKCA	S473	P478H	478	Missense	distal	5	no	18.312	18.034	EPSD	TCGA;COSMIC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	P28329	CHAT	P17252	PRKCA	S473	R470Q	470	Missense	distal	-3	no	18.312	15.454	EPSD	TCGA;COSMIC	16.704	Loss
AGC_PKC_PKCa_PRKCA_ST	P28329	CHAT	P17252	PRKCA	S473	R466K	466	Missense	distal	-7	no	18.312	18.307	EPSD	TCGA;COSMIC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	P28329	CHAT	P17252	PRKCA	S473	E476K	476	Missense	distal	3	no	18.312	18.928	EPSD	TCGA;COSMIC	16.704	Up-regulation
AGC_PKC_PKCa_PRKCA_ST	P28329	CHAT	P17252	PRKCA	S558	A557V	557	Missense	proximal	-1	no	19.146	18.242	EPSD	TCGA;COSMIC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	P28329	CHAT	P17252	PRKCA	S558	P552L	552	Missense	distal	-6	no	19.146	19.112	EPSD	TCGA;COSMIC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	P28329	CHAT	P17252	PRKCA	S558	S556R	556	Missense	proximal	-2	no	19.146	22.448	EPSD	TCGA;COSMIC	16.704	Up-regulation
AGC_PKC_PKCa_PRKCA_ST	P28329	CHAT	P17252	PRKCA	S558	G565E	565	Missense	distal	7	no	19.146	19.075	EPSD	TCGA;COSMIC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	P06401	PGR	P17252	PRKCA	S190	L197F	197	Missense	distal	7	no	19.015	18.949	EPSD	TCGA;ICGC;COSMIC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	P06401	PGR	P17252	PRKCA	S276	S276L	276	Missense	central	0	yes	17.207	0.000	EPSD	TCGA;ICGC;COSMIC;CCLE	16.704	Loss
AGC_PKC_PKCa_PRKCA_ST	P06401	PGR	P17252	PRKCA	S276	R274H	274	Missense	proximal	-2	no	17.207	12.653	EPSD	TCGA;ICGC;COSMIC	16.704	Loss
AGC_PKC_PKCa_PRKCA_ST	P06401	PGR	P17252	PRKCA	S400	A394V	394	Missense	distal	-6	no	17.185	17.108	PhosphoSitePlus	TCGA;ICGC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	Q8N556	AFAP1	P17252	PRKCA	S278	S282C	282	Missense	distal	4	no	19.144	17.989	EPSD	TCGA;ICGC;COSMIC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	Q8N556	AFAP1	P17252	PRKCA	S307	K305N	305	Missense	proximal	-2	no	22.757	21.189	EPSD	TCGA;COSMIC;GDSC;CCLE	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	Q8N556	AFAP1	P17252	PRKCA	S308	K305N	305	Missense	distal	-3	no	17.992	15.792	EPSD	TCGA;COSMIC;GDSC;CCLE	16.704	Loss
AGC_PKC_PKCa_PRKCA_ST	Q8N556	AFAP1	P17252	PRKCA	S510	S510L	510	Missense	central	0	yes	17.799	0.000	EPSD	TCGA;ICGC;COSMIC	16.704	Loss
AGC_PKC_PKCa_PRKCA_ST	Q8N556	AFAP1	P17252	PRKCA	S510	D503N	503	Missense	distal	-7	no	17.799	17.798	EPSD	TCGA;ICGC;COSMIC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	Q8N556	AFAP1	P17252	PRKCA	S510	G509S	509	Missense	proximal	-1	no	17.799	17.551	EPSD	TCGA;ICGC;COSMIC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	Q96T49	PPP1R16B	P17252	PRKCA	S56	R55H	55	Missense	proximal	-1	no	19.577	19.254	EPSD	TCGA;ICGC;COSMIC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	Q96T49	PPP1R16B	P17252	PRKCA	S56	R61H	61	Missense	distal	5	no	19.577	19.317	EPSD	TCGA;ICGC;COSMIC;GDSC;CCLE	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	Q96T49	PPP1R16B	P17252	PRKCA	S56	R60C	60	Missense	distal	4	no	19.577	18.175	EPSD	TCGA;ICGC;COSMIC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	Q96T49	PPP1R16B	P17252	PRKCA	S56	G59D	59	Missense	distal	3	no	19.577	18.491	EPSD	TCGA;ICGC;COSMIC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	Q96T49	PPP1R16B	P17252	PRKCA	S324	I321M	321	Missense	distal	-3	no	15.578	17.093	EPSD	TCGA;COSMIC	16.704	Gain
AGC_PKC_PKCa_PRKCA_ST	Q96T49	PPP1R16B	P17252	PRKCA	S331	S338N	338	Missense	distal	7	no	18.024	18.001	PhosphoSitePlus	TCGA;COSMIC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	Q96T49	PPP1R16B	P17252	PRKCA	S331	S338R	338	Missense	distal	7	no	18.024	18.071	PhosphoSitePlus	TCGA;COSMIC	16.704	Up-regulation
AGC_PKC_PKCa_PRKCA_ST	Q96T49	PPP1R16B	P17252	PRKCA	S331	R334W	334	Missense	distal	3	no	18.024	15.091	PhosphoSitePlus	TCGA;COSMIC;GDSC;CCLE	16.704	Loss
AGC_PKC_PKCa_PRKCA_ST	Q96T49	PPP1R16B	P17252	PRKCA	S331	S333R	333	Missense	proximal	2	no	18.024	22.644	PhosphoSitePlus	TCGA	16.704	Up-regulation
AGC_PKC_PKCa_PRKCA_ST	Q96T49	PPP1R16B	P17252	PRKCA	S350	T355I	355	Missense	distal	5	no	18.950	18.932	EPSD	TCGA;COSMIC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	Q96T49	PPP1R16B	P17252	PRKCA	S476	E474K	474	Missense	proximal	-2	no	14.780	17.279	EPSD	TCGA;COSMIC	16.704	Gain
AGC_PKC_PKCa_PRKCA_ST	Q8TD43	TRPM4	P17252	PRKCA	S94	R96Q	96	Missense	proximal	2	no	20.175	16.340	EPSD	TCGA;ICGC;COSMIC	16.704	Loss
AGC_PKC_PKCa_PRKCA_ST	Q8TD43	TRPM4	P17252	PRKCA	S94	R92W	92	Missense	proximal	-2	no	20.175	18.177	EPSD	TCGA;ICGC;COSMIC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	Q8TD43	TRPM4	P17252	PRKCA	S94	L93F	93	Missense	proximal	-1	no	20.175	19.886	EPSD	TCGA;ICGC;COSMIC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	Q8TD43	TRPM4	P17252	PRKCA	S94	L91F	91	Missense	distal	-3	no	20.175	21.910	EPSD	TCGA;ICGC;COSMIC	16.704	Up-regulation
AGC_PKC_PKCa_PRKCA_ST	Q8TD43	TRPM4	P17252	PRKCA	S255	R248H	248	Missense	distal	-7	no	19.561	19.554	EPSD	TCGA;ICGC;COSMIC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	Q8TD43	TRPM4	P17252	PRKCA	S541	S541L	541	Missense	central	0	yes	18.869	0.000	EPSD	TCGA;COSMIC	16.704	Loss
AGC_PKC_PKCa_PRKCA_ST	Q8TD43	TRPM4	P17252	PRKCA	S541	M537I	537	Missense	distal	-4	no	18.869	18.155	EPSD	TCGA;ICGC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	Q8TD43	TRPM4	P17252	PRKCA	S1143	R1147H	1147	Missense	distal	4	no	16.763	16.481	EPSD	TCGA;ICGC;COSMIC	16.704	Loss
AGC_PKC_PKCa_PRKCA_ST	Q8TD43	TRPM4	P17252	PRKCA	S1143	D1144G	1144	Missense	proximal	1	no	16.763	17.409	EPSD	TCGA;ICGC;COSMIC	16.704	Up-regulation
AGC_PKC_PKCa_PRKCA_ST	Q8TD43	TRPM4	P17252	PRKCA	S1143	E1146K	1146	Missense	distal	3	no	16.763	17.379	EPSD	TCGA;ICGC	16.704	Up-regulation
AGC_PKC_PKCa_PRKCA_ST	Q8TD43	TRPM4	P17252	PRKCA	S1145	E1146K	1146	Missense	proximal	1	no	15.257	16.861	EPSD;PhosphoSitePlus	TCGA;ICGC	16.704	Gain
AGC_PKC_PKCa_PRKCA_ST	Q8TD43	TRPM4	P17252	PRKCA	S1152	D1156N	1156	Missense	distal	4	no	20.781	20.424	PhosphoSitePlus;EPSD	TCGA;COSMIC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	Q8TD43	TRPM4	P17252	PRKCA	S1152	R1147H	1147	Missense	distal	-5	no	20.781	20.426	PhosphoSitePlus;EPSD	TCGA;ICGC;COSMIC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	Q8TD43	TRPM4	P17252	PRKCA	S1152	E1146K	1146	Missense	distal	-6	no	20.781	20.849	PhosphoSitePlus;EPSD	TCGA;ICGC	16.704	Up-regulation
AGC_PKC_PKCa_PRKCA_ST	Q969H0	FBXW7	P17252	PRKCA	S10	R14Q	14	Missense	distal	4	no	25.231	25.013	PhosphoSitePlus;EPSD	TCGA;ICGC;COSMIC;GDSC;CCLE	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	Q969H0	FBXW7	P17252	PRKCA	S10	V8L	8	Missense	proximal	-2	no	25.231	25.385	PhosphoSitePlus;EPSD	TCGA;ICGC;COSMIC	16.704	Up-regulation
AGC_PKC_PKCa_PRKCA_ST	Q969H0	FBXW7	P17252	PRKCA	S10	G9S	9	Missense	proximal	-1	no	25.231	24.983	PhosphoSitePlus;EPSD	TCGA;ICGC;COSMIC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	Q969H0	FBXW7	P17252	PRKCA	S10	V8M	8	Missense	proximal	-2	no	25.231	26.091	PhosphoSitePlus;EPSD	TCGA;ICGC;COSMIC	16.704	Up-regulation
AGC_PKC_PKCa_PRKCA_ST	Q969H0	FBXW7	P17252	PRKCA	S18	R14Q	14	Missense	distal	-4	no	20.808	20.431	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC;GDSC;CCLE	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	Q969H0	FBXW7	P17252	PRKCA	S227	G233C	233	Missense	distal	6	no	19.658	19.568	EPSD	TCGA;ICGC;COSMIC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	P13726	F3	P17252	PRKCA	T171	S174R	174	Missense	distal	3	no	15.542	16.933	EPSD	TCGA;ICGC;COSMIC	16.704	Gain
AGC_PKC_PKCa_PRKCA_ST	P13726	F3	P17252	PRKCA	S174	L175I	175	Missense	proximal	1	no	15.921	16.758	EPSD	TCGA;ICGC;COSMIC	16.704	Gain
AGC_PKC_PKCa_PRKCA_ST	Q9NPC2	KCNK9	P17252	PRKCA	T134	K141M	141	Missense	distal	7	no	17.526	17.441	EPSD	TCGA;ICGC;COSMIC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	Q9NPC2	KCNK9	P17252	PRKCA	T134	R131C	131	Missense	distal	-3	no	17.526	14.787	EPSD	TCGA;ICGC;COSMIC;CCLE	16.704	Loss
AGC_PKC_PKCa_PRKCA_ST	Q9NPC2	KCNK9	P17252	PRKCA	T134	M132I	132	Missense	proximal	-2	no	17.526	15.920	EPSD	TCGA;ICGC;COSMIC	16.704	Loss
AGC_PKC_PKCa_PRKCA_ST	Q9NPC2	KCNK9	P17252	PRKCA	T134	L128M	128	Missense	distal	-6	no	17.526	17.589	EPSD	TCGA;ICGC;COSMIC	16.704	Up-regulation
AGC_PKC_PKCa_PRKCA_ST	Q9NPC2	KCNK9	P17252	PRKCA	T134	G129C	129	Missense	distal	-5	no	17.526	17.141	EPSD	TCGA;ICGC;COSMIC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	Q9NPC2	KCNK9	P17252	PRKCA	T134	V136L	136	Missense	proximal	2	no	17.526	17.554	EPSD	TCGA;ICGC;COSMIC	16.704	Up-regulation
AGC_PKC_PKCa_PRKCA_ST	Q9NPC2	KCNK9	P17252	PRKCA	T134	R131H	131	Missense	distal	-3	no	17.526	13.670	EPSD	TCGA;ICGC	16.704	Loss
AGC_PKC_PKCa_PRKCA_ST	Q9NPC2	KCNK9	P17252	PRKCA	T134	V136M	136	Missense	proximal	2	no	17.526	18.093	EPSD	TCGA;ICGC;COSMIC	16.704	Up-regulation
AGC_PKC_PKCa_PRKCA_ST	Q9NPC2	KCNK9	P17252	PRKCA	T341	E335K	335	Missense	distal	-6	no	17.927	17.994	PhosphoSitePlus	TCGA;ICGC;COSMIC	16.704	Up-regulation
AGC_PKC_PKCa_PRKCA_ST	Q9NPC2	KCNK9	P17252	PRKCA	T341	S345I	345	Missense	distal	4	no	17.927	16.482	PhosphoSitePlus	TCGA;ICGC;COSMIC	16.704	Loss
AGC_PKC_PKCa_PRKCA_ST	Q9NPC2	KCNK9	P17252	PRKCA	T341	E336D	336	Missense	distal	-5	no	17.927	17.849	PhosphoSitePlus	TCGA;ICGC;COSMIC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	Q9NPC2	KCNK9	P17252	PRKCA	T341	E336K	336	Missense	distal	-5	no	17.927	18.221	PhosphoSitePlus	TCGA;ICGC;COSMIC	16.704	Up-regulation
AGC_PKC_PKCa_PRKCA_ST	Q9NPC2	KCNK9	P17252	PRKCA	T341	S340N	340	Missense	proximal	-1	no	17.927	17.769	PhosphoSitePlus	TCGA;ICGC;COSMIC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	Q9NPC2	KCNK9	P17252	PRKCA	S373	R370H	370	Missense	distal	-3	no	16.743	12.887	EPSD	TCGA;ICGC;COSMIC	16.704	Loss
AGC_PKC_PKCa_PRKCA_ST	Q9NPC2	KCNK9	P17252	PRKCA	S373	R371Q	371	Missense	proximal	-2	no	16.743	14.984	EPSD	TCGA;ICGC;COSMIC;GDSC;CCLE	16.704	Loss
AGC_PKC_PKCa_PRKCA_ST	Q9NPC2	KCNK9	P17252	PRKCA	S373	M368I	368	Missense	distal	-5	no	16.743	16.338	EPSD	TCGA;ICGC;COSMIC	16.704	Loss
AGC_PKC_PKCa_PRKCA_ST	Q9NPC2	KCNK9	P17252	PRKCA	S373	K372T	372	Missense	proximal	-1	no	16.743	15.921	EPSD	TCGA;ICGC;COSMIC	16.704	Loss
AGC_PKC_PKCa_PRKCA_ST	Q14184	DOC2B	P17252	PRKCA	S273	R269H	269	Missense	distal	-4	no	17.391	16.816	EPSD	TCGA;ICGC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	Q14184	DOC2B	P17252	PRKCA	S273	R267W	267	Missense	distal	-6	no	17.391	17.106	EPSD	TCGA;ICGC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	Q12959	DLG1	P17252	PRKCA	S23	E26K	26	Missense	distal	3	no	18.137	18.753	EPSD	TCGA;ICGC;COSMIC	16.704	Up-regulation
AGC_PKC_PKCa_PRKCA_ST	Q12959	DLG1	P17252	PRKCA	S232	F236L	236	Missense	distal	4	no	18.156	17.725	EPSD	TCGA;COSMIC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	Q12959	DLG1	P17252	PRKCA	S435	A442V	442	Missense	distal	7	no	17.292	17.238	EPSD	TCGA;COSMIC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	Q12959	DLG1	P17252	PRKCA	S435	D428H	428	Missense	distal	-7	no	17.292	17.295	EPSD	TCGA;COSMIC	16.704	Up-regulation
AGC_PKC_PKCa_PRKCA_ST	Q12959	DLG1	P17252	PRKCA	S435	S432G	432	Missense	distal	-3	no	17.292	16.900	EPSD	TCGA;COSMIC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	Q12959	DLG1	P17252	PRKCA	S567	S568I	568	Missense	proximal	1	no	15.743	17.406	EPSD	TCGA;COSMIC	16.704	Gain
AGC_PKC_PKCa_PRKCA_ST	Q12959	DLG1	P17252	PRKCA	S575	S568I	568	Missense	distal	-7	no	18.992	18.983	EPSD	TCGA;COSMIC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	Q12959	DLG1	P17252	PRKCA	S575	G574C	574	Missense	proximal	-1	no	18.992	16.471	EPSD	TCGA;COSMIC	16.704	Loss
AGC_PKC_PKCa_PRKCA_ST	Q12959	DLG1	P17252	PRKCA	S579	G574C	574	Missense	distal	-5	no	21.263	20.878	EPSD	TCGA;COSMIC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	Q12959	DLG1	P17252	PRKCA	S583	R587I	587	Missense	distal	4	no	18.178	16.487	EPSD	TCGA;COSMIC	16.704	Loss
AGC_PKC_PKCa_PRKCA_ST	Q12959	DLG1	P17252	PRKCA	S643	R645C	645	Missense	proximal	2	no	18.485	14.135	EPSD	TCGA;COSMIC	16.704	Loss
AGC_PKC_PKCa_PRKCA_ST	Q12959	DLG1	P17252	PRKCA	S643	E648V	648	Missense	distal	5	no	18.485	18.332	EPSD	TCGA;COSMIC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	Q12959	DLG1	P17252	PRKCA	T657	T664M	664	Missense	distal	7	no	20.821	20.825	PhosphoSitePlus	TCGA;COSMIC	16.704	Up-regulation
AGC_PKC_PKCa_PRKCA_ST	Q12959	DLG1	P17252	PRKCA	T657	S662Y	662	Missense	distal	5	no	20.821	20.848	PhosphoSitePlus	TCGA;COSMIC	16.704	Up-regulation
AGC_PKC_PKCa_PRKCA_ST	Q5NUL3	FFAR4	P17252	PRKCA	S253	T258M	258	Missense	distal	5	no	19.689	19.992	EPSD	TCGA;ICGC;COSMIC	16.704	Up-regulation
AGC_PKC_PKCa_PRKCA_ST	Q5NUL3	FFAR4	P17252	PRKCA	S366	V367I	367	Missense	proximal	1	no	16.198	16.910	EPSD	TCGA;ICGC;COSMIC	16.704	Gain
AGC_PKC_PKCa_PRKCA_ST	Q5NUL3	FFAR4	P17252	PRKCA	S366	D364Y	364	Missense	proximal	-2	no	16.198	16.889	EPSD	TCGA;ICGC	16.704	Gain
AGC_PKC_PKCa_PRKCA_ST	P41180	CASR	P17252	PRKCA	S182	Q179K	179	Missense	distal	-3	no	15.908	16.739	EPSD	TCGA;ICGC	16.704	Gain
AGC_PKC_PKCa_PRKCA_ST	P41180	CASR	P17252	PRKCA	S895	R896Q	896	Missense	proximal	1	no	19.647	19.530	EPSD	TCGA;COSMIC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	P41180	CASR	P17252	PRKCA	S895	R896W	896	Missense	proximal	1	no	19.647	18.923	EPSD	TCGA;COSMIC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	P41180	CASR	P17252	PRKCA	S899	R896Q	896	Missense	distal	-3	no	17.285	14.427	EPSD	TCGA;COSMIC	16.704	Loss
AGC_PKC_PKCa_PRKCA_ST	P41180	CASR	P17252	PRKCA	S899	R896W	896	Missense	distal	-3	no	17.285	14.931	EPSD	TCGA;COSMIC	16.704	Loss
AGC_PKC_PKCa_PRKCA_ST	P41180	CASR	P17252	PRKCA	S900	R896Q	896	Missense	distal	-4	no	17.164	16.787	EPSD	TCGA;COSMIC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	P41180	CASR	P17252	PRKCA	S900	R896W	896	Missense	distal	-4	no	17.164	16.338	EPSD	TCGA;COSMIC	16.704	Loss
AGC_PKC_PKCa_PRKCA_ST	P41180	CASR	P17252	PRKCA	S901	R896Q	896	Missense	distal	-5	no	16.908	16.756	EPSD	TCGA;COSMIC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	P41180	CASR	P17252	PRKCA	S901	R896W	896	Missense	distal	-5	no	16.908	16.594	EPSD	TCGA;COSMIC	16.704	Loss
AGC_PKC_PKCa_PRKCA_ST	Q04206	RELA	P17252	PRKCA	S131	E127K	127	Missense	distal	-4	no	16.531	17.262	EPSD	TCGA;ICGC;COSMIC	16.704	Gain
AGC_PKC_PKCa_PRKCA_ST	Q04206	RELA	P17252	PRKCA	S276	S276F	276	Missense	central	0	yes	20.996	0.000	EPSD	TCGA;ICGC;COSMIC	16.704	Loss
AGC_PKC_PKCa_PRKCA_ST	Q04206	RELA	P17252	PRKCA	S276	R274W	274	Missense	proximal	-2	no	20.996	18.999	EPSD	TCGA;ICGC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	Q04206	RELA	P17252	PRKCA	S276	R273W	273	Missense	distal	-3	no	20.996	18.642	EPSD	TCGA;ICGC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	Q04206	RELA	P17252	PRKCA	T305	E307K	307	Missense	proximal	2	no	15.709	20.988	EPSD	TCGA;ICGC;COSMIC	16.704	Gain
AGC_PKC_PKCa_PRKCA_ST	Q8NFA2	NOXO1	P17252	PRKCA	S159	S152P	152	Missense	distal	-7	no	17.846	17.843	EPSD	TCGA;COSMIC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	Q8NFA2	NOXO1	P17252	PRKCA	S159	G156C	156	Missense	distal	-3	no	17.846	18.368	EPSD	TCGA;COSMIC	16.704	Up-regulation
AGC_PKC_PKCa_PRKCA_ST	Q99623	PHB2	P17252	PRKCA	S39	G46R	46	Missense	distal	7	no	17.637	17.661	PhosphoSitePlus	TCGA;ICGC;COSMIC	16.704	Up-regulation
AGC_PKC_PKCa_PRKCA_ST	Q99623	PHB2	P17252	PRKCA	S105	I104V	104	Missense	proximal	-1	no	16.893	16.714	EPSD	TCGA;ICGC;COSMIC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	Q99623	PHB2	P17252	PRKCA	S105	L106Q	106	Missense	proximal	1	no	16.893	17.124	EPSD	TCGA;ICGC;COSMIC	16.704	Up-regulation
AGC_PKC_PKCa_PRKCA_ST	Q99623	PHB2	P17252	PRKCA	S105	N103S	103	Missense	proximal	-2	no	16.893	16.787	EPSD	TCGA;ICGC;COSMIC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	Q99623	PHB2	P17252	PRKCA	S267	N269K	269	Missense	proximal	2	no	12.199	17.148	EPSD	TCGA;COSMIC	16.704	Gain
AGC_PKC_PKCa_PRKCA_ST	P16070	CD44	P17252	PRKCA	S182	S180R	180	Missense	proximal	-2	no	13.903	17.205	EPSD	TCGA;ICGC;COSMIC	16.704	Gain
AGC_PKC_PKCa_PRKCA_ST	P16070	CD44	P17252	PRKCA	S578	P575S	575	Missense	distal	-3	no	15.976	16.954	EPSD	TCGA;COSMIC	16.704	Gain
AGC_PKC_PKCa_PRKCA_ST	O14939	PLD2	P17252	PRKCA	T99	D95N	95	Missense	distal	-4	no	16.543	16.891	EPSD	TCGA;ICGC;COSMIC	16.704	Gain
AGC_PKC_PKCa_PRKCA_ST	O14939	PLD2	P17252	PRKCA	T100	D95N	95	Missense	distal	-5	no	17.878	17.907	EPSD	TCGA;ICGC;COSMIC	16.704	Up-regulation
AGC_PKC_PKCa_PRKCA_ST	O14939	PLD2	P17252	PRKCA	S155	R149W	149	Missense	distal	-6	no	18.533	18.249	EPSD	TCGA;ICGC;COSMIC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	O14939	PLD2	P17252	PRKCA	S155	P152S	152	Missense	distal	-3	no	18.533	19.512	EPSD	TCGA;ICGC	16.704	Up-regulation
AGC_PKC_PKCa_PRKCA_ST	O14939	PLD2	P17252	PRKCA	S213	R212C	212	Missense	proximal	-1	no	19.804	17.144	EPSD	TCGA;ICGC;COSMIC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	O14939	PLD2	P17252	PRKCA	S213	R217H	217	Missense	distal	4	no	19.804	19.522	EPSD	TCGA;ICGC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	O14939	PLD2	P17252	PRKCA	S213	H216Y	216	Missense	distal	3	no	19.804	18.249	EPSD	TCGA;ICGC;COSMIC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	O14939	PLD2	P17252	PRKCA	T274	R277W	277	Missense	distal	3	no	17.364	14.431	EPSD	TCGA;ICGC;COSMIC;GDSC;CCLE	16.704	Loss
AGC_PKC_PKCa_PRKCA_ST	O14939	PLD2	P17252	PRKCA	T274	H278L	278	Missense	distal	4	no	17.364	16.608	EPSD	TCGA;ICGC;COSMIC	16.704	Loss
AGC_PKC_PKCa_PRKCA_ST	O14939	PLD2	P17252	PRKCA	S416	A419V	419	Missense	distal	3	no	19.446	19.189	EPSD	TCGA;ICGC;COSMIC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	O14939	PLD2	P17252	PRKCA	S814	S814N	814	Missense	central	0	yes	18.723	0.000	EPSD	TCGA;ICGC;COSMIC	16.704	Loss
AGC_PKC_PKCa_PRKCA_ST	Q5JVS0	HABP4	P17252	PRKCA	T121	R120W	120	Missense	proximal	-1	no	18.879	17.294	EPSD	TCGA;ICGC;COSMIC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	Q5JVS0	HABP4	P17252	PRKCA	T375	R369H	369	Missense	distal	-6	no	18.122	18.054	PhosphoSitePlus;EPSD	TCGA;COSMIC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	Q5JVS0	HABP4	P17252	PRKCA	T375	G377E	377	Missense	proximal	2	no	18.122	17.666	PhosphoSitePlus;EPSD	TCGA;COSMIC;GDSC;CCLE	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	Q9BZL6	PRKD2	P17252	PRKCA	S197	R195C	195	Missense	proximal	-2	no	17.772	16.072	EPSD	TCGA;COSMIC	16.704	Loss
AGC_PKC_PKCa_PRKCA_ST	Q9BZL6	PRKD2	P17252	PRKCA	S197	K193E	193	Missense	distal	-4	no	17.772	17.041	EPSD	TCGA;COSMIC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	Q9BZL6	PRKD2	P17252	PRKCA	S197	S203T	203	Missense	distal	6	no	17.772	17.723	EPSD	TCGA;COSMIC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	Q9BZL6	PRKD2	P17252	PRKCA	S197	R195H	195	Missense	proximal	-2	no	17.772	13.218	EPSD	TCGA;COSMIC	16.704	Loss
AGC_PKC_PKCa_PRKCA_ST	Q9BZL6	PRKD2	P17252	PRKCA	S197	R192H	192	Missense	distal	-5	no	17.772	17.416	EPSD	TCGA	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	Q9BZL6	PRKD2	P17252	PRKCA	S197	R194W	194	Missense	distal	-3	no	17.772	15.418	EPSD	TCGA	16.704	Loss
AGC_PKC_PKCa_PRKCA_ST	Q9BZL6	PRKD2	P17252	PRKCA	S197	T199M	199	Missense	proximal	2	no	17.772	18.134	EPSD	TCGA	16.704	Up-regulation
AGC_PKC_PKCa_PRKCA_ST	Q9BZL6	PRKD2	P17252	PRKCA	S198	R195C	195	Missense	distal	-3	no	19.167	16.428	EPSD	TCGA;COSMIC	16.704	Loss
AGC_PKC_PKCa_PRKCA_ST	Q9BZL6	PRKD2	P17252	PRKCA	S198	K193E	193	Missense	distal	-5	no	19.167	18.873	EPSD	TCGA;COSMIC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	Q9BZL6	PRKD2	P17252	PRKCA	S198	S203T	203	Missense	distal	5	no	19.167	18.992	EPSD	TCGA;COSMIC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	Q9BZL6	PRKD2	P17252	PRKCA	S198	R195H	195	Missense	distal	-3	no	19.167	15.311	EPSD	TCGA;COSMIC	16.704	Loss
AGC_PKC_PKCa_PRKCA_ST	Q9BZL6	PRKD2	P17252	PRKCA	S198	R192H	192	Missense	distal	-6	no	19.167	19.100	EPSD	TCGA	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	Q9BZL6	PRKD2	P17252	PRKCA	S198	R194W	194	Missense	distal	-4	no	19.167	18.341	EPSD	TCGA	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	Q9BZL6	PRKD2	P17252	PRKCA	S198	T199M	199	Missense	proximal	1	no	19.167	19.452	EPSD	TCGA	16.704	Up-regulation
AGC_PKC_PKCa_PRKCA_ST	Q9BZL6	PRKD2	P17252	PRKCA	S206	S206L	206	Missense	central	0	yes	18.452	0.000	EPSD	TCGA;COSMIC	16.704	Loss
AGC_PKC_PKCa_PRKCA_ST	Q9BZL6	PRKD2	P17252	PRKCA	S206	S203T	203	Missense	distal	-3	no	18.452	17.159	EPSD	TCGA;COSMIC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	Q9BZL6	PRKD2	P17252	PRKCA	S206	T211N	211	Missense	distal	5	no	18.452	18.407	EPSD	TCGA;COSMIC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	Q9BZL6	PRKD2	P17252	PRKCA	S206	T199M	199	Missense	distal	-7	no	18.452	18.458	EPSD	TCGA	16.704	Up-regulation
AGC_PKC_PKCa_PRKCA_ST	Q9BZL6	PRKD2	P17252	PRKCA	T226	E228K	228	Missense	proximal	2	no	13.932	19.212	EPSD	TCGA;COSMIC;CCLE	16.704	Gain
AGC_PKC_PKCa_PRKCA_ST	Q9BZL6	PRKD2	P17252	PRKCA	T227	E228K	228	Missense	proximal	1	no	15.811	17.415	EPSD	TCGA;COSMIC;CCLE	16.704	Gain
AGC_PKC_PKCa_PRKCA_ST	Q9BZL6	PRKD2	P17252	PRKCA	S387	P380L	380	Missense	distal	-7	no	20.777	20.774	EPSD	TCGA;COSMIC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	Q9BZL6	PRKD2	P17252	PRKCA	S387	R393W	393	Missense	distal	6	no	20.777	20.529	EPSD	TCGA;COSMIC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	Q9BZL6	PRKD2	P17252	PRKCA	S387	M382T	382	Missense	distal	-5	no	20.777	20.844	EPSD	TCGA;COSMIC	16.704	Up-regulation
AGC_PKC_PKCa_PRKCA_ST	Q9BZL6	PRKD2	P17252	PRKCA	T391	R393W	393	Missense	proximal	2	no	22.239	16.799	EPSD	TCGA;COSMIC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	Q9BZL6	PRKD2	P17252	PRKCA	T392	R393W	393	Missense	proximal	1	no	17.971	17.247	EPSD	TCGA;COSMIC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	Q9BZL6	PRKD2	P17252	PRKCA	T412	N409I	409	Missense	distal	-3	no	17.328	17.067	EPSD	TCGA;COSMIC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	Q9BZL6	PRKD2	P17252	PRKCA	T412	L413P	413	Missense	proximal	1	no	17.328	16.901	EPSD	TCGA;COSMIC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	Q9BZL6	PRKD2	P17252	PRKCA	T412	S408N	408	Missense	distal	-4	no	17.328	16.998	EPSD	TCGA;COSMIC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	Q9BZL6	PRKD2	P17252	PRKCA	S529	S529F	529	Missense	central	0	yes	16.922	0.000	EPSD	TCGA;COSMIC	16.704	Loss
AGC_PKC_PKCa_PRKCA_ST	Q9BZL6	PRKD2	P17252	PRKCA	S706	R709H	709	Missense	distal	3	no	20.420	19.708	EPSD;PhosphoSitePlus	TCGA;COSMIC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	Q9BZL6	PRKD2	P17252	PRKCA	S706	S706L	706	Missense	central	0	yes	20.420	0.000	EPSD;PhosphoSitePlus	TCGA;COSMIC	16.704	Loss
AGC_PKC_PKCa_PRKCA_ST	Q9BZL6	PRKD2	P17252	PRKCA	S710	A716T	716	Missense	distal	6	no	20.269	20.191	EPSD;PhosphoSitePlus	TCGA;COSMIC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	Q9BZL6	PRKD2	P17252	PRKCA	S710	R709H	709	Missense	proximal	-1	no	20.269	19.946	EPSD;PhosphoSitePlus	TCGA;COSMIC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	Q9BZL6	PRKD2	P17252	PRKCA	S710	S706L	706	Missense	distal	-4	no	20.269	19.838	EPSD;PhosphoSitePlus	TCGA;COSMIC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	Q9BZL6	PRKD2	P17252	PRKCA	S710	P715S	715	Missense	distal	5	no	20.269	20.109	EPSD;PhosphoSitePlus	TCGA;COSMIC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	Q9BZL6	PRKD2	P17252	PRKCA	S797	R793H	793	Missense	distal	-4	no	20.685	20.111	EPSD	TCGA;COSMIC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	Q9BZL6	PRKD2	P17252	PRKCA	S797	K794T	794	Missense	distal	-3	no	20.685	18.548	EPSD	TCGA	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	Q9BZL6	PRKD2	P17252	PRKCA	S797	S801F	801	Missense	distal	4	no	20.685	20.323	EPSD	TCGA;COSMIC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	Q9BZL6	PRKD2	P17252	PRKCA	S797	R795H	795	Missense	proximal	-2	no	20.685	16.131	EPSD	TCGA;COSMIC	16.704	Loss
AGC_PKC_PKCa_PRKCA_ST	Q9BZL6	PRKD2	P17252	PRKCA	S797	S803G	803	Missense	distal	6	no	20.685	20.607	EPSD	TCGA;COSMIC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	Q13002	GRIK2	P17252	PRKCA	S361	T357A	357	Missense	distal	-4	no	16.683	17.432	EPSD	TCGA;COSMIC	16.704	Gain
AGC_PKC_PKCa_PRKCA_ST	Q13002	GRIK2	P17252	PRKCA	S416	G410V	410	Missense	distal	-6	no	21.070	20.990	EPSD	TCGA;ICGC;COSMIC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	Q13002	GRIK2	P17252	PRKCA	S416	G410C	410	Missense	distal	-6	no	21.070	20.808	EPSD	TCGA;ICGC;COSMIC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	Q13002	GRIK2	P17252	PRKCA	S666	P667H	667	Missense	proximal	1	no	18.976	18.937	EPSD	TCGA;ICGC;COSMIC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	Q13002	GRIK2	P17252	PRKCA	S666	M664I	664	Missense	proximal	-2	no	18.976	17.369	EPSD	TCGA;ICGC;COSMIC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	Q13002	GRIK2	P17252	PRKCA	S697	F694L	694	Missense	distal	-3	no	17.665	15.930	EPSD	TCGA	16.704	Loss
AGC_PKC_PKCa_PRKCA_ST	Q13002	GRIK2	P17252	PRKCA	S697	I699L	699	Missense	proximal	2	no	17.665	17.710	EPSD	TCGA;ICGC;COSMIC	16.704	Up-regulation
AGC_PKC_PKCa_PRKCA_ST	Q13002	GRIK2	P17252	PRKCA	S697	S697L	697	Missense	central	0	yes	17.665	0.000	EPSD	TCGA;COSMIC;GDSC;CCLE	16.704	Loss
AGC_PKC_PKCa_PRKCA_ST	Q13002	GRIK2	P17252	PRKCA	S715	V716A	716	Missense	proximal	1	no	20.252	20.098	EPSD	TCGA;ICGC;COSMIC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	Q13002	GRIK2	P17252	PRKCA	S715	K719N	719	Missense	distal	4	no	20.252	19.125	EPSD	TCGA;ICGC;COSMIC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	Q13002	GRIK2	P17252	PRKCA	S715	R713S	713	Missense	proximal	-2	no	20.252	16.950	EPSD	TCGA;COSMIC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	Q13002	GRIK2	P17252	PRKCA	S715	S710R	710	Missense	distal	-5	no	20.252	20.678	EPSD	TCGA;ICGC;COSMIC	16.704	Up-regulation
AGC_PKC_PKCa_PRKCA_ST	Q13002	GRIK2	P17252	PRKCA	S846	Q851H	851	Missense	distal	5	no	19.804	19.553	EPSD	TCGA;ICGC;COSMIC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	Q13002	GRIK2	P17252	PRKCA	S846	A850T	850	Missense	distal	4	no	19.804	19.357	EPSD	TCGA;ICGC;COSMIC;GDSC;CCLE	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	Q13002	GRIK2	P17252	PRKCA	S846	A850D	850	Missense	distal	4	no	19.804	19.435	EPSD	TCGA;ICGC;COSMIC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	Q13002	GRIK2	P17252	PRKCA	S846	Y844C	844	Missense	proximal	-2	no	19.804	20.832	EPSD	TCGA;ICGC;COSMIC	16.704	Up-regulation
AGC_PKC_PKCa_PRKCA_ST	Q13002	GRIK2	P17252	PRKCA	S846	F842Y	842	Missense	distal	-4	no	19.804	19.669	EPSD	TCGA;ICGC;COSMIC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	Q13002	GRIK2	P17252	PRKCA	S868	R874P	874	Missense	distal	6	no	22.309	22.271	PhosphoSitePlus	TCGA;COSMIC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	Q13002	GRIK2	P17252	PRKCA	S868	K870N	870	Missense	proximal	2	no	22.309	17.360	PhosphoSitePlus	TCGA;COSMIC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	Q13002	GRIK2	P17252	PRKCA	S868	R873C	873	Missense	distal	5	no	22.309	21.577	PhosphoSitePlus	TCGA;ICGC;COSMIC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	P45379	TNNT2	P17252	PRKCA	T204	K200E	200	Missense	distal	-4	no	19.034	18.303	EPSD	TCGA;COSMIC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	Q96C90	PPP1R14B	P17252	PRKCA	T57	V50L	50	Missense	distal	-7	no	16.993	16.995	PhosphoSitePlus	TCGA;ICGC;COSMIC	16.704	Up-regulation
AGC_PKC_PKCa_PRKCA_ST	Q09472	EP300	P17252	PRKCA	S12	K14Q	14	Missense	proximal	2	no	22.214	18.802	EPSD	TCGA;ICGC;COSMIC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	Q09472	EP300	P17252	PRKCA	S12	K17E	17	Missense	distal	5	no	22.214	21.800	EPSD	TCGA;ICGC;COSMIC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	Q09472	EP300	P17252	PRKCA	S12	E7G	7	Missense	distal	-5	no	22.214	22.231	EPSD	TCGA;ICGC;COSMIC	16.704	Up-regulation
AGC_PKC_PKCa_PRKCA_ST	Q09472	EP300	P17252	PRKCA	S20	K14Q	14	Missense	distal	-6	no	16.832	16.696	EPSD	TCGA;ICGC;COSMIC	16.704	Loss
AGC_PKC_PKCa_PRKCA_ST	Q09472	EP300	P17252	PRKCA	S20	K17E	17	Missense	distal	-3	no	16.832	13.920	EPSD	TCGA;ICGC;COSMIC	16.704	Loss
AGC_PKC_PKCa_PRKCA_ST	Q09472	EP300	P17252	PRKCA	S20	A25P	25	Missense	distal	5	no	16.832	16.888	EPSD	TCGA;ICGC;COSMIC	16.704	Up-regulation
AGC_PKC_PKCa_PRKCA_ST	Q09472	EP300	P17252	PRKCA	S20	P21A	21	Missense	proximal	1	no	16.832	17.230	EPSD	TCGA;ICGC;COSMIC	16.704	Up-regulation
AGC_PKC_PKCa_PRKCA_ST	Q09472	EP300	P17252	PRKCA	S384	A391T	391	Missense	distal	7	no	16.999	17.008	EPSD	TCGA;ICGC;COSMIC	16.704	Up-regulation
AGC_PKC_PKCa_PRKCA_ST	Q09472	EP300	P17252	PRKCA	S395	S395F	395	Missense	central	0	yes	16.913	0.000	EPSD	TCGA;ICGC;COSMIC	16.704	Loss
AGC_PKC_PKCa_PRKCA_ST	Q09472	EP300	P17252	PRKCA	S395	A391T	391	Missense	distal	-4	no	16.913	16.165	EPSD	TCGA;ICGC;COSMIC	16.704	Loss
AGC_PKC_PKCa_PRKCA_ST	Q09472	EP300	P17252	PRKCA	S1044	P1039L	1039	Missense	distal	-5	no	17.120	17.094	EPSD	TCGA;ICGC;COSMIC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	Q09472	EP300	P17252	PRKCA	S1044	K1045N	1045	Missense	proximal	1	no	17.120	15.956	EPSD	TCGA;ICGC;COSMIC;CCLE	16.704	Loss
AGC_PKC_PKCa_PRKCA_ST	Q09472	EP300	P17252	PRKCA	T1135	Y1139C	1139	Missense	distal	4	no	18.975	18.217	EPSD	TCGA;ICGC;COSMIC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	Q09472	EP300	P17252	PRKCA	S1193	D1188H	1188	Missense	distal	-5	no	17.037	17.067	EPSD	TCGA;ICGC;COSMIC	16.704	Up-regulation
AGC_PKC_PKCa_PRKCA_ST	Q09472	EP300	P17252	PRKCA	S1193	F1200L	1200	Missense	distal	7	no	17.037	17.104	EPSD	TCGA;ICGC;COSMIC	16.704	Up-regulation
AGC_PKC_PKCa_PRKCA_ST	Q09472	EP300	P17252	PRKCA	S1193	Y1198F	1198	Missense	distal	5	no	17.037	17.045	EPSD	TCGA;ICGC;COSMIC	16.704	Up-regulation
AGC_PKC_PKCa_PRKCA_ST	Q09472	EP300	P17252	PRKCA	S1193	A1189V	1189	Missense	distal	-4	no	17.037	16.478	EPSD	TCGA;ICGC;COSMIC	16.704	Loss
AGC_PKC_PKCa_PRKCA_ST	Q09472	EP300	P17252	PRKCA	S1193	H1199Y	1199	Missense	distal	6	no	17.037	17.062	EPSD	TCGA;ICGC;COSMIC	16.704	Up-regulation
AGC_PKC_PKCa_PRKCA_ST	Q09472	EP300	P17252	PRKCA	S1581	L1584P	1584	Missense	distal	3	no	16.285	16.992	EPSD	TCGA;ICGC;COSMIC	16.704	Gain
AGC_PKC_PKCa_PRKCA_ST	Q09472	EP300	P17252	PRKCA	S1730	R1737C	1737	Missense	distal	7	no	18.150	17.927	EPSD	TCGA;ICGC;COSMIC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	Q09472	EP300	P17252	PRKCA	S1730	I1735T	1735	Missense	distal	5	no	18.150	18.168	EPSD	TCGA;ICGC	16.704	Up-regulation
AGC_PKC_PKCa_PRKCA_ST	Q09472	EP300	P17252	PRKCA	S1734	I1739M	1739	Missense	distal	5	no	21.175	21.496	EPSD	TCGA;ICGC;COSMIC	16.704	Up-regulation
AGC_PKC_PKCa_PRKCA_ST	Q09472	EP300	P17252	PRKCA	S1734	R1737C	1737	Missense	distal	3	no	21.175	18.556	EPSD	TCGA;ICGC;COSMIC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	Q09472	EP300	P17252	PRKCA	S1734	I1735T	1735	Missense	proximal	1	no	21.175	19.839	EPSD	TCGA;ICGC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	Q09472	EP300	P17252	PRKCA	S1834	R1829C	1829	Missense	distal	-5	no	20.807	20.131	EPSD	TCGA;ICGC;COSMIC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	Q09472	EP300	P17252	PRKCA	S1834	R1830S	1830	Missense	distal	-4	no	20.807	20.614	EPSD	TCGA;ICGC;COSMIC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	Q09472	EP300	P17252	PRKCA	S1834	L1828F	1828	Missense	distal	-6	no	20.807	20.787	EPSD	TCGA;ICGC;COSMIC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	Q09472	EP300	P17252	PRKCA	S2315	R2308C	2308	Missense	distal	-7	no	16.834	16.814	EPSD	TCGA;ICGC;COSMIC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	Q09472	EP300	P17252	PRKCA	S2315	R2317Q	2317	Missense	proximal	2	no	16.834	12.999	EPSD	TCGA;ICGC;COSMIC	16.704	Loss
AGC_PKC_PKCa_PRKCA_ST	Q09472	EP300	P17252	PRKCA	S2315	R2317L	2317	Missense	proximal	2	no	16.834	11.847	EPSD	TCGA;ICGC;COSMIC	16.704	Loss
AGC_PKC_PKCa_PRKCA_ST	Q09472	EP300	P17252	PRKCA	S2320	R2317Q	2317	Missense	distal	-3	no	17.549	14.691	EPSD	TCGA;ICGC;COSMIC	16.704	Loss
AGC_PKC_PKCa_PRKCA_ST	Q09472	EP300	P17252	PRKCA	S2320	P2327H	2327	Missense	distal	7	no	17.549	17.488	EPSD	TCGA;ICGC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	Q09472	EP300	P17252	PRKCA	S2320	R2317L	2317	Missense	distal	-3	no	17.549	13.193	EPSD	TCGA;ICGC;COSMIC	16.704	Loss
AGC_PKC_PKCa_PRKCA_ST	Q09472	EP300	P17252	PRKCA	S2328	P2327H	2327	Missense	proximal	-1	no	19.642	20.006	EPSD	TCGA;ICGC	16.704	Up-regulation
AGC_PKC_PKCa_PRKCA_ST	O14920	IKBKB	P17252	PRKCA	S2	T9M	9	Missense	distal	7	no	17.577	17.581	EPSD	TCGA;COSMIC	16.704	Up-regulation
AGC_PKC_PKCa_PRKCA_ST	O14920	IKBKB	P17252	PRKCA	S2	S2N	2	Missense	central	0	yes	17.577	0.000	EPSD	TCGA;ICGC;COSMIC	16.704	Loss
AGC_PKC_PKCa_PRKCA_ST	O14920	IKBKB	P17252	PRKCA	S6	T9M	9	Missense	distal	3	no	17.791	18.359	EPSD	TCGA;COSMIC	16.704	Up-regulation
AGC_PKC_PKCa_PRKCA_ST	O14920	IKBKB	P17252	PRKCA	S6	S2N	2	Missense	distal	-4	no	17.791	17.461	EPSD	TCGA;ICGC;COSMIC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	O14920	IKBKB	P17252	PRKCA	S239	Q237R	237	Missense	proximal	-2	no	16.568	18.327	EPSD	TCGA;COSMIC	16.704	Gain
AGC_PKC_PKCa_PRKCA_ST	O14920	IKBKB	P17252	PRKCA	S335	L336F	336	Missense	proximal	1	no	19.790	20.448	EPSD	TCGA;COSMIC	16.704	Up-regulation
AGC_PKC_PKCa_PRKCA_ST	O14920	IKBKB	P17252	PRKCA	S335	K337N	337	Missense	proximal	2	no	19.790	14.841	EPSD	TCGA;GDSC;CCLE	16.704	Loss
AGC_PKC_PKCa_PRKCA_ST	O14920	IKBKB	P17252	PRKCA	S402	E398D	398	Missense	distal	-4	no	18.581	18.406	EPSD	TCGA;COSMIC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	O14920	IKBKB	P17252	PRKCA	S489	F486L	486	Missense	distal	-3	no	17.149	15.414	EPSD	TCGA;COSMIC	16.704	Loss
AGC_PKC_PKCa_PRKCA_ST	O14920	IKBKB	P17252	PRKCA	S489	D484N	484	Missense	distal	-5	no	17.149	17.178	EPSD	TCGA;COSMIC	16.704	Up-regulation
AGC_PKC_PKCa_PRKCA_ST	O14920	IKBKB	P17252	PRKCA	S489	K482T	482	Missense	distal	-7	no	17.149	17.146	EPSD	TCGA;COSMIC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	O14920	IKBKB	P17252	PRKCA	S489	S489N	489	Missense	central	0	yes	17.149	0.000	EPSD	TCGA;COSMIC	16.704	Loss
AGC_PKC_PKCa_PRKCA_ST	O14920	IKBKB	P17252	PRKCA	S682	S689C	689	Missense	distal	7	no	18.847	18.670	EPSD	TCGA;COSMIC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	O14920	IKBKB	P17252	PRKCA	S682	R680Q	680	Missense	proximal	-2	no	18.847	17.088	EPSD	TCGA;COSMIC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	O14920	IKBKB	P17252	PRKCA	S692	Q690E	690	Missense	proximal	-2	no	17.166	14.799	EPSD	TCGA;COSMIC	16.704	Loss
AGC_PKC_PKCa_PRKCA_ST	O14920	IKBKB	P17252	PRKCA	S692	S689C	689	Missense	distal	-3	no	17.166	17.297	EPSD	TCGA;COSMIC	16.704	Up-regulation
AGC_PKC_PKCa_PRKCA_ST	O14920	IKBKB	P17252	PRKCA	S692	A694T	694	Missense	proximal	2	no	17.166	17.054	EPSD	TCGA	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	Q8N0W4	NLGN4X	P17252	PRKCA	T249	K246Q	246	Missense	distal	-3	no	17.149	16.318	EPSD	TCGA;ICGC;COSMIC	16.704	Loss
AGC_PKC_PKCa_PRKCA_ST	Q8N0W4	NLGN4X	P17252	PRKCA	T249	S253P	253	Missense	distal	4	no	17.149	16.950	EPSD	TCGA	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	Q8N0W4	NLGN4X	P17252	PRKCA	T249	S253L	253	Missense	distal	4	no	17.149	16.357	EPSD	TCGA;ICGC	16.704	Loss
AGC_PKC_PKCa_PRKCA_ST	Q8N0W4	NLGN4X	P17252	PRKCA	T249	G243R	243	Missense	distal	-6	no	17.149	17.257	EPSD	TCGA;ICGC;COSMIC	16.704	Up-regulation
AGC_PKC_PKCa_PRKCA_ST	Q8N0W4	NLGN4X	P17252	PRKCA	T249	V248L	248	Missense	proximal	-1	no	17.149	18.193	EPSD	TCGA;ICGC;COSMIC	16.704	Up-regulation
AGC_PKC_PKCa_PRKCA_ST	Q8N0W4	NLGN4X	P17252	PRKCA	T249	D244V	244	Missense	distal	-5	no	17.149	16.971	EPSD	TCGA;ICGC;COSMIC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	Q8N0W4	NLGN4X	P17252	PRKCA	T249	D244Y	244	Missense	distal	-5	no	17.149	17.026	EPSD	TCGA;ICGC;COSMIC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	Q8N0W4	NLGN4X	P17252	PRKCA	T249	G252C	252	Missense	distal	3	no	17.149	15.171	EPSD	TCGA;ICGC;COSMIC	16.704	Loss
AGC_PKC_PKCa_PRKCA_ST	Q8N0W4	NLGN4X	P17252	PRKCA	T249	F251L	251	Missense	proximal	2	no	17.149	16.466	EPSD	TCGA;ICGC;COSMIC	16.704	Loss
AGC_PKC_PKCa_PRKCA_ST	Q8N0W4	NLGN4X	P17252	PRKCA	T635	A630T	630	Missense	distal	-5	no	16.557	16.938	EPSD	TCGA;ICGC;COSMIC	16.704	Gain
AGC_PKC_PKCa_PRKCA_ST	Q8N0W4	NLGN4X	P17252	PRKCA	T636	T642I	642	Missense	distal	6	no	17.602	17.616	EPSD	TCGA;ICGC	16.704	Up-regulation
AGC_PKC_PKCa_PRKCA_ST	Q8N0W4	NLGN4X	P17252	PRKCA	T636	A630T	630	Missense	distal	-6	no	17.602	17.513	EPSD	TCGA;ICGC;COSMIC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	Q8N0W4	NLGN4X	P17252	PRKCA	T636	I632L	632	Missense	distal	-4	no	17.602	17.613	EPSD	TCGA;ICGC;COSMIC;GDSC;CCLE	16.704	Up-regulation
AGC_PKC_PKCa_PRKCA_ST	Q8N0W4	NLGN4X	P17252	PRKCA	S672	E674K	674	Missense	proximal	2	no	15.065	20.344	EPSD	TCGA;ICGC;COSMIC;CCLE	16.704	Gain
AGC_PKC_PKCa_PRKCA_ST	Q8N0W4	NLGN4X	P17252	PRKCA	T707	R709W	709	Missense	proximal	2	no	21.286	15.846	PhosphoSitePlus	TCGA;ICGC;COSMIC	16.704	Loss
AGC_PKC_PKCa_PRKCA_ST	Q8N0W4	NLGN4X	P17252	PRKCA	T707	R710P	710	Missense	distal	3	no	21.286	19.755	PhosphoSitePlus	TCGA;ICGC;COSMIC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	Q8N0W4	NLGN4X	P17252	PRKCA	T707	D701E	701	Missense	distal	-6	no	21.286	21.369	PhosphoSitePlus	TCGA;ICGC;COSMIC	16.704	Up-regulation
AGC_PKC_PKCa_PRKCA_ST	Q8N0W4	NLGN4X	P17252	PRKCA	T707	P713H	713	Missense	distal	6	no	21.286	21.247	PhosphoSitePlus	TCGA;ICGC;COSMIC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	Q8N0W4	NLGN4X	P17252	PRKCA	T707	R710C	710	Missense	distal	3	no	21.286	18.668	PhosphoSitePlus	TCGA;ICGC;COSMIC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	Q8N0W4	NLGN4X	P17252	PRKCA	T707	D701N	701	Missense	distal	-6	no	21.286	21.313	PhosphoSitePlus	TCGA;ICGC;COSMIC	16.704	Up-regulation
AGC_PKC_PKCa_PRKCA_ST	Q8N0W4	NLGN4X	P17252	PRKCA	T707	D701Y	701	Missense	distal	-6	no	21.286	21.317	PhosphoSitePlus	TCGA;ICGC;COSMIC	16.704	Up-regulation
AGC_PKC_PKCa_PRKCA_ST	Q8N0W4	NLGN4X	P17252	PRKCA	T707	R704H	704	Missense	distal	-3	no	21.286	17.430	PhosphoSitePlus	TCGA;ICGC;COSMIC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	Q8N0W4	NLGN4X	P17252	PRKCA	T707	H708R	708	Missense	proximal	1	no	21.286	22.099	PhosphoSitePlus	TCGA;ICGC;COSMIC	16.704	Up-regulation
AGC_PKC_PKCa_PRKCA_ST	Q8N0W4	NLGN4X	P17252	PRKCA	T707	R704C	704	Missense	distal	-3	no	21.286	18.547	PhosphoSitePlus	TCGA;ICGC;COSMIC;GDSC;CCLE	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	Q8N0W4	NLGN4X	P17252	PRKCA	S712	R709W	709	Missense	distal	-3	no	22.370	20.016	EPSD	TCGA;ICGC;COSMIC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	Q8N0W4	NLGN4X	P17252	PRKCA	S712	T718K	718	Missense	distal	6	no	22.370	22.477	EPSD	TCGA;ICGC;COSMIC	16.704	Up-regulation
AGC_PKC_PKCa_PRKCA_ST	Q8N0W4	NLGN4X	P17252	PRKCA	S712	R710P	710	Missense	proximal	-2	no	22.370	19.327	EPSD	TCGA;ICGC;COSMIC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	Q8N0W4	NLGN4X	P17252	PRKCA	S712	P713H	713	Missense	proximal	1	no	22.370	22.331	EPSD	TCGA;ICGC;COSMIC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	Q8N0W4	NLGN4X	P17252	PRKCA	S712	R710C	710	Missense	proximal	-2	no	22.370	20.670	EPSD	TCGA;ICGC;COSMIC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	Q8N0W4	NLGN4X	P17252	PRKCA	S712	H708R	708	Missense	distal	-4	no	22.370	22.944	EPSD	TCGA;ICGC;COSMIC	16.704	Up-regulation
AGC_PKC_PKCa_PRKCA_ST	P49407	ARRB1	P17252	PRKCA	S163	R169W	169	Missense	distal	6	no	21.728	21.480	PhosphoSitePlus	TCGA;ICGC;COSMIC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	P49407	ARRB1	P17252	PRKCA	S163	R165C	165	Missense	proximal	2	no	21.728	17.378	PhosphoSitePlus	TCGA;ICGC;COSMIC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	P08567	PLEK	P17252	PRKCA	S16	Y10F	10	Missense	distal	-6	no	18.941	18.909	EPSD	TCGA;ICGC;COSMIC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	P08567	PLEK	P17252	PRKCA	S16	G15A	15	Missense	proximal	-1	no	18.941	18.134	EPSD	TCGA;ICGC;COSMIC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	P08567	PLEK	P17252	PRKCA	S113	R111S	111	Missense	proximal	-2	no	22.977	19.675	PhosphoSitePlus;EPSD	TCGA;ICGC;COSMIC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	P08567	PLEK	P17252	PRKCA	S113	T114S	114	Missense	proximal	1	no	22.977	22.650	PhosphoSitePlus;EPSD	TCGA;ICGC;COSMIC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	P08567	PLEK	P17252	PRKCA	S113	A110D	110	Missense	distal	-3	no	22.977	22.383	PhosphoSitePlus;EPSD	TCGA;ICGC;COSMIC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	P08567	PLEK	P17252	PRKCA	S113	R119P	119	Missense	distal	6	no	22.977	22.938	PhosphoSitePlus;EPSD	TCGA;ICGC;COSMIC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	P08567	PLEK	P17252	PRKCA	S113	R115W	115	Missense	proximal	2	no	22.977	17.537	PhosphoSitePlus;EPSD	TCGA;ICGC;COSMIC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	P08567	PLEK	P17252	PRKCA	S113	K108T	108	Missense	distal	-5	no	22.977	22.890	PhosphoSitePlus;EPSD	TCGA;ICGC;COSMIC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	P08567	PLEK	P17252	PRKCA	S113	A110T	110	Missense	distal	-3	no	22.977	23.262	PhosphoSitePlus;EPSD	TCGA;ICGC;COSMIC	16.704	Up-regulation
AGC_PKC_PKCa_PRKCA_ST	P08567	PLEK	P17252	PRKCA	S113	R119Q	119	Missense	distal	6	no	22.977	22.854	PhosphoSitePlus;EPSD	TCGA;ICGC;COSMIC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	P08567	PLEK	P17252	PRKCA	T114	R111S	111	Missense	distal	-3	no	21.199	18.329	EPSD	TCGA;ICGC;COSMIC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	P08567	PLEK	P17252	PRKCA	T114	A110D	110	Missense	distal	-4	no	21.199	20.433	EPSD	TCGA;ICGC;COSMIC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	P08567	PLEK	P17252	PRKCA	T114	R119P	119	Missense	distal	5	no	21.199	21.216	EPSD	TCGA;ICGC;COSMIC	16.704	Up-regulation
AGC_PKC_PKCa_PRKCA_ST	P08567	PLEK	P17252	PRKCA	T114	R115W	115	Missense	proximal	1	no	21.199	20.475	EPSD	TCGA;ICGC;COSMIC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	P08567	PLEK	P17252	PRKCA	T114	K108T	108	Missense	distal	-6	no	21.199	21.007	EPSD	TCGA;ICGC;COSMIC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	P08567	PLEK	P17252	PRKCA	T114	A110T	110	Missense	distal	-4	no	21.199	20.450	EPSD	TCGA;ICGC;COSMIC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	P08567	PLEK	P17252	PRKCA	T114	R119Q	119	Missense	distal	5	no	21.199	21.190	EPSD	TCGA;ICGC;COSMIC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	P08567	PLEK	P17252	PRKCA	S117	R111S	111	Missense	distal	-6	no	22.507	22.434	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	P08567	PLEK	P17252	PRKCA	S117	T114S	114	Missense	distal	-3	no	22.507	23.800	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	16.704	Up-regulation
AGC_PKC_PKCa_PRKCA_ST	P08567	PLEK	P17252	PRKCA	S117	A110D	110	Missense	distal	-7	no	22.507	22.501	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	P08567	PLEK	P17252	PRKCA	S117	R119P	119	Missense	proximal	2	no	22.507	17.304	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	P08567	PLEK	P17252	PRKCA	S117	R115W	115	Missense	proximal	-2	no	22.507	20.510	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	P08567	PLEK	P17252	PRKCA	S117	A110T	110	Missense	distal	-7	no	22.507	22.502	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	P08567	PLEK	P17252	PRKCA	S117	R119Q	119	Missense	proximal	2	no	22.507	18.673	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	P08567	PLEK	P17252	PRKCA	S132	M133I	133	Missense	proximal	1	no	17.855	18.905	EPSD	TCGA;ICGC;COSMIC	16.704	Up-regulation
AGC_PKC_PKCa_PRKCA_ST	P08567	PLEK	P17252	PRKCA	S132	T136N	136	Missense	distal	4	no	17.855	17.575	EPSD	TCGA;ICGC;COSMIC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	P08567	PLEK	P17252	PRKCA	S132	D135Y	135	Missense	distal	3	no	17.855	17.312	EPSD	TCGA;ICGC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	P08567	PLEK	P17252	PRKCA	T136	E142K	142	Missense	distal	6	no	16.674	16.768	EPSD	TCGA;ICGC;COSMIC	16.704	Gain
AGC_PKC_PKCa_PRKCA_ST	P08567	PLEK	P17252	PRKCA	T136	D135Y	135	Missense	proximal	-1	no	16.674	16.720	EPSD	TCGA;ICGC	16.704	Gain
AGC_PKC_PKCa_PRKCA_ST	O60500	NPHS1	P17252	PRKCA	T305	M304I	304	Missense	proximal	-1	no	19.529	17.586	EPSD	TCGA;ICGC;COSMIC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	O60500	NPHS1	P17252	PRKCA	T305	E309D	309	Missense	distal	4	no	19.529	19.298	EPSD	TCGA;ICGC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	O60500	NPHS1	P17252	PRKCA	T305	T305I	305	Missense	central	0	yes	19.529	0.000	EPSD	TCGA;ICGC;COSMIC	16.704	Loss
AGC_PKC_PKCa_PRKCA_ST	P09693	CD3G	P17252	PRKCA	S145	K150N	150	Missense	distal	5	no	17.931	17.425	EPSD	TCGA;COSMIC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	P09693	CD3G	P17252	PRKCA	S145	Q151H	151	Missense	distal	6	no	17.931	17.977	EPSD	TCGA;COSMIC	16.704	Up-regulation
AGC_PKC_PKCa_PRKCA_ST	P09693	CD3G	P17252	PRKCA	S148	K150N	150	Missense	proximal	2	no	20.548	15.599	PhosphoSitePlus	TCGA;COSMIC	16.704	Loss
AGC_PKC_PKCa_PRKCA_ST	P09693	CD3G	P17252	PRKCA	S148	Q151H	151	Missense	distal	3	no	20.548	22.289	PhosphoSitePlus	TCGA;COSMIC	16.704	Up-regulation
AGC_PKC_PKCa_PRKCA_ST	Q16875	PFKFB3	P17252	PRKCA	S273	G270D	270	Missense	distal	-3	no	17.002	15.222	EPSD	TCGA;COSMIC	16.704	Loss
AGC_PKC_PKCa_PRKCA_ST	Q16875	PFKFB3	P17252	PRKCA	S273	S273N	273	Missense	central	0	yes	17.002	0.000	EPSD	TCGA;ICGC;COSMIC	16.704	Loss
AGC_PKC_PKCa_PRKCA_ST	Q16875	PFKFB3	P17252	PRKCA	S273	G275C	275	Missense	proximal	2	no	17.002	17.897	EPSD	TCGA;ICGC;COSMIC	16.704	Up-regulation
AGC_PKC_PKCa_PRKCA_ST	Q16875	PFKFB3	P17252	PRKCA	S461	S461C	461	Missense	central	0	yes	20.088	0.000	PhosphoSitePlus	TCGA;COSMIC	16.704	Loss
AGC_PKC_PKCa_PRKCA_ST	Q16875	PFKFB3	P17252	PRKCA	S461	P464L	464	Missense	distal	3	no	20.088	19.381	PhosphoSitePlus	TCGA;COSMIC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	Q16875	PFKFB3	P17252	PRKCA	S461	N460Y	460	Missense	proximal	-1	no	20.088	19.796	PhosphoSitePlus	TCGA;COSMIC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	Q16875	PFKFB3	P17252	PRKCA	S478	R475G	475	Missense	distal	-3	no	16.721	13.459	EPSD	TCGA;COSMIC	16.704	Loss
AGC_PKC_PKCa_PRKCA_ST	P41091	EIF2S3	P17252	PRKCA	S444	H450Y	450	Missense	distal	6	no	17.904	17.929	EPSD	TCGA;ICGC;COSMIC	16.704	Up-regulation
AGC_PKC_PKCa_PRKCA_ST	P41091	EIF2S3	P17252	PRKCA	S444	K449N	449	Missense	distal	5	no	17.904	17.397	EPSD	TCGA;ICGC;COSMIC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	Q13418	ILK	P17252	PRKCA	T172	T173A	173	Missense	proximal	1	no	19.539	20.010	EPSD	TCGA;ICGC;COSMIC	16.704	Up-regulation
AGC_PKC_PKCa_PRKCA_ST	Q13418	ILK	P17252	PRKCA	T181	H185Q	185	Missense	distal	4	no	17.480	17.545	PhosphoSitePlus;EPSD	TCGA;ICGC	16.704	Up-regulation
AGC_PKC_PKCa_PRKCA_ST	Q13418	ILK	P17252	PRKCA	S228	K231N	231	Missense	distal	3	no	20.836	19.889	EPSD	TCGA;ICGC;COSMIC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	Q13418	ILK	P17252	PRKCA	S228	R225Q	225	Missense	distal	-3	no	20.836	17.978	EPSD	TCGA;COSMIC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	Q13418	ILK	P17252	PRKCA	T229	K231N	231	Missense	proximal	2	no	17.591	12.642	EPSD	TCGA;ICGC;COSMIC	16.704	Loss
AGC_PKC_PKCa_PRKCA_ST	Q13418	ILK	P17252	PRKCA	T229	R225Q	225	Missense	distal	-4	no	17.591	17.214	EPSD	TCGA;COSMIC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	Q13769	THOC5	P17252	PRKCA	S2	R9G	9	Missense	distal	7	no	17.083	17.058	EPSD	TCGA;ICGC;COSMIC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	Q13769	THOC5	P17252	PRKCA	S2	S5L	5	Missense	distal	3	no	17.083	16.236	EPSD	TCGA;ICGC;COSMIC	16.704	Loss
AGC_PKC_PKCa_PRKCA_ST	Q13769	THOC5	P17252	PRKCA	S2	R9W	9	Missense	distal	7	no	17.083	16.902	EPSD	TCGA;ICGC;COSMIC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	Q13769	THOC5	P17252	PRKCA	S5	R9G	9	Missense	distal	4	no	22.892	22.288	PhosphoSitePlus;EPSD	TCGA;ICGC;COSMIC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	Q13769	THOC5	P17252	PRKCA	S5	S5L	5	Missense	central	0	yes	22.892	0.000	PhosphoSitePlus;EPSD	TCGA;ICGC;COSMIC	16.704	Loss
AGC_PKC_PKCa_PRKCA_ST	Q13769	THOC5	P17252	PRKCA	S5	R9W	9	Missense	distal	4	no	22.892	21.356	PhosphoSitePlus;EPSD	TCGA;ICGC;COSMIC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	Q13769	THOC5	P17252	PRKCA	S6	R9G	9	Missense	distal	3	no	23.433	22.793	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	Q13769	THOC5	P17252	PRKCA	S6	S5L	5	Missense	proximal	-1	no	23.433	23.013	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	Q13769	THOC5	P17252	PRKCA	S6	V13G	13	Missense	distal	7	no	23.433	23.511	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	16.704	Up-regulation
AGC_PKC_PKCa_PRKCA_ST	Q13769	THOC5	P17252	PRKCA	S6	R9W	9	Missense	distal	3	no	23.433	20.499	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	Q13769	THOC5	P17252	PRKCA	S210	R206Q	206	Missense	distal	-4	no	17.406	17.029	EPSD	TCGA;ICGC;COSMIC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	Q13769	THOC5	P17252	PRKCA	S210	E213D	213	Missense	distal	3	no	17.406	16.920	EPSD	TCGA;ICGC;COSMIC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	Q13769	THOC5	P17252	PRKCA	S210	K214N	214	Missense	distal	4	no	17.406	16.279	EPSD	TCGA;ICGC;COSMIC	16.704	Loss
AGC_PKC_PKCa_PRKCA_ST	Q13769	THOC5	P17252	PRKCA	S210	L216I	216	Missense	distal	6	no	17.406	17.383	EPSD	TCGA;ICGC;COSMIC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	Q13769	THOC5	P17252	PRKCA	S210	L209I	209	Missense	proximal	-1	no	17.406	16.543	EPSD	TCGA;ICGC;COSMIC	16.704	Loss
AGC_PKC_PKCa_PRKCA_ST	Q13769	THOC5	P17252	PRKCA	T322	T322M	322	Missense	central	0	yes	19.085	0.000	EPSD	TCGA;ICGC;COSMIC	16.704	Loss
AGC_PKC_PKCa_PRKCA_ST	Q13769	THOC5	P17252	PRKCA	T322	A316V	316	Missense	distal	-6	no	19.085	19.008	EPSD	TCGA;ICGC;COSMIC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	Q13769	THOC5	P17252	PRKCA	T328	D335N	335	Missense	distal	7	no	18.431	18.405	EPSD	TCGA;ICGC;COSMIC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	Q13769	THOC5	P17252	PRKCA	T328	T322M	322	Missense	distal	-6	no	18.431	18.554	EPSD	TCGA;ICGC;COSMIC	16.704	Up-regulation
AGC_PKC_PKCa_PRKCA_ST	Q12791	KCNMA1	P17252	PRKCA	S511	H516P	516	Missense	distal	5	no	21.348	21.626	EPSD	TCGA;ICGC	16.704	Up-regulation
AGC_PKC_PKCa_PRKCA_ST	Q12791	KCNMA1	P17252	PRKCA	S511	K513N	513	Missense	proximal	2	no	21.348	16.399	EPSD	TCGA;ICGC;COSMIC	16.704	Loss
AGC_PKC_PKCa_PRKCA_ST	Q12791	KCNMA1	P17252	PRKCA	S511	I506M	506	Missense	distal	-5	no	21.348	21.753	EPSD	TCGA;ICGC;COSMIC	16.704	Up-regulation
AGC_PKC_PKCa_PRKCA_ST	Q12791	KCNMA1	P17252	PRKCA	S1200	S1204F	1204	Missense	distal	4	no	20.403	20.042	PhosphoSitePlus	TCGA;ICGC;COSMIC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	Q12791	KCNMA1	P17252	PRKCA	S1203	S1204F	1204	Missense	proximal	1	no	15.279	16.762	EPSD	TCGA;ICGC;COSMIC	16.704	Gain
AGC_PKC_PKCa_PRKCA_ST	P09211	GSTP1	P17252	PRKCA	S28	E31K	31	Missense	distal	3	no	18.535	19.151	EPSD	TCGA;ICGC;COSMIC	16.704	Up-regulation
AGC_PKC_PKCa_PRKCA_ST	P09211	GSTP1	P17252	PRKCA	S43	Y50H	50	Missense	distal	7	no	17.670	17.651	EPSD	TCGA;ICGC;COSMIC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	P09211	GSTP1	P17252	PRKCA	S185	R183P	183	Missense	proximal	-2	no	19.779	16.737	PhosphoSitePlus	TCGA;ICGC;COSMIC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	P09211	GSTP1	P17252	PRKCA	S185	R183H	183	Missense	proximal	-2	no	19.779	15.225	PhosphoSitePlus	TCGA;ICGC;COSMIC	16.704	Loss
AGC_PKC_PKCa_PRKCA_ST	P09211	GSTP1	P17252	PRKCA	S185	S178L	178	Missense	distal	-7	no	19.779	19.773	PhosphoSitePlus	TCGA;ICGC;COSMIC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	P09211	GSTP1	P17252	PRKCA	S185	R183C	183	Missense	proximal	-2	no	19.779	18.079	PhosphoSitePlus	TCGA;ICGC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	Q01970	PLCB3	P17252	PRKCA	S68	D65N	65	Missense	distal	-3	no	18.185	19.000	EPSD	TCGA	16.704	Up-regulation
AGC_PKC_PKCa_PRKCA_ST	Q01970	PLCB3	P17252	PRKCA	S68	T74A	74	Missense	distal	6	no	18.185	18.263	EPSD	TCGA;ICGC	16.704	Up-regulation
AGC_PKC_PKCa_PRKCA_ST	Q01970	PLCB3	P17252	PRKCA	T758	D757N	757	Missense	proximal	-1	no	16.454	16.791	EPSD	TCGA;ICGC;COSMIC	16.704	Gain
AGC_PKC_PKCa_PRKCA_ST	Q01970	PLCB3	P17252	PRKCA	S793	R795C	795	Missense	proximal	2	no	18.275	13.925	EPSD	TCGA;ICGC;COSMIC	16.704	Loss
AGC_PKC_PKCa_PRKCA_ST	Q01970	PLCB3	P17252	PRKCA	S1105	A1109S	1109	Missense	distal	4	no	18.595	18.579	PhosphoSitePlus	TCGA	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	Q01995	TAGLN	P17252	PRKCA	S7	E13K	13	Missense	distal	6	no	18.512	18.606	EPSD	TCGA;ICGC;COSMIC	16.704	Up-regulation
AGC_PKC_PKCa_PRKCA_ST	Q01995	TAGLN	P17252	PRKCA	S11	E13K	13	Missense	proximal	2	no	14.947	20.227	EPSD	TCGA;ICGC;COSMIC	16.704	Gain
AGC_PKC_PKCa_PRKCA_ST	Q01995	TAGLN	P17252	PRKCA	S16	E13K	13	Missense	distal	-3	no	15.398	18.311	EPSD	TCGA;ICGC;COSMIC	16.704	Gain
AGC_PKC_PKCa_PRKCA_ST	O94759	TRPM2	P17252	PRKCA	S11	S11L	11	Missense	central	0	yes	18.101	0.000	EPSD	TCGA;ICGC;COSMIC	16.704	Loss
AGC_PKC_PKCa_PRKCA_ST	O94759	TRPM2	P17252	PRKCA	S11	E14K	14	Missense	distal	3	no	18.101	18.717	EPSD	TCGA;ICGC;COSMIC	16.704	Up-regulation
AGC_PKC_PKCa_PRKCA_ST	O94759	TRPM2	P17252	PRKCA	S11	E14D	14	Missense	distal	3	no	18.101	17.614	EPSD	TCGA;ICGC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	O94759	TRPM2	P17252	PRKCA	S38	S39R	39	Missense	proximal	1	no	15.672	16.845	EPSD	TCGA	16.704	Gain
AGC_PKC_PKCa_PRKCA_ST	O94759	TRPM2	P17252	PRKCA	S603	S606Y	606	Missense	distal	3	no	16.880	16.003	EPSD	TCGA;ICGC;COSMIC	16.704	Loss
AGC_PKC_PKCa_PRKCA_ST	O94759	TRPM2	P17252	PRKCA	S603	G601R	601	Missense	proximal	-2	no	16.880	19.752	EPSD	TCGA;ICGC;COSMIC	16.704	Up-regulation
AGC_PKC_PKCa_PRKCA_ST	O94759	TRPM2	P17252	PRKCA	S612	S606Y	606	Missense	distal	-6	no	17.161	17.107	EPSD	TCGA;ICGC;COSMIC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	O94759	TRPM2	P17252	PRKCA	S612	T618I	618	Missense	distal	6	no	17.161	17.175	EPSD	TCGA;ICGC;COSMIC	16.704	Up-regulation
AGC_PKC_PKCa_PRKCA_ST	O94759	TRPM2	P17252	PRKCA	S612	H614N	614	Missense	proximal	2	no	17.161	16.814	EPSD	TCGA;ICGC;COSMIC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	O94759	TRPM2	P17252	PRKCA	S772	L765R	765	Missense	distal	-7	no	18.648	18.659	EPSD	TCGA;ICGC;COSMIC	16.704	Up-regulation
AGC_PKC_PKCa_PRKCA_ST	O94759	TRPM2	P17252	PRKCA	S772	R777K	777	Missense	distal	5	no	18.648	18.792	EPSD	TCGA;ICGC;COSMIC	16.704	Up-regulation
AGC_PKC_PKCa_PRKCA_ST	O94759	TRPM2	P17252	PRKCA	S1152	E1149K	1149	Missense	distal	-3	no	15.245	18.157	EPSD	TCGA;ICGC	16.704	Gain
AGC_PKC_PKCa_PRKCA_ST	O94901	SUN1	P17252	PRKCA	S52	R57C	57	Missense	distal	5	no	22.535	21.803	EPSD	TCGA;ICGC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	O94901	SUN1	P17252	PRKCA	S55	R57C	57	Missense	proximal	2	no	23.780	19.429	PhosphoSitePlus	TCGA;ICGC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	Q9C0K0	BCL11B	P17252	PRKCA	S2	P9L	9	Missense	distal	7	no	24.765	24.732	PhosphoSitePlus	TCGA;ICGC;COSMIC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	Q9C0K0	BCL11B	P17252	PRKCA	S13	P9L	9	Missense	distal	-4	no	19.791	19.532	EPSD	TCGA;ICGC;COSMIC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	Q9C0K0	BCL11B	P17252	PRKCA	S101	E105K	105	Missense	distal	4	no	17.717	18.256	EPSD	TCGA;ICGC;COSMIC	16.704	Up-regulation
AGC_PKC_PKCa_PRKCA_ST	Q9C0K0	BCL11B	P17252	PRKCA	S101	R103H	103	Missense	proximal	2	no	17.717	12.693	EPSD	TCGA;ICGC	16.704	Loss
AGC_PKC_PKCa_PRKCA_ST	Q9C0K0	BCL11B	P17252	PRKCA	S101	S104C	104	Missense	distal	3	no	17.717	16.489	EPSD	TCGA;ICGC;COSMIC	16.704	Loss
AGC_PKC_PKCa_PRKCA_ST	Q9C0K0	BCL11B	P17252	PRKCA	S104	E105K	105	Missense	proximal	1	no	15.179	16.783	EPSD	TCGA;ICGC;COSMIC	16.704	Gain
AGC_PKC_PKCa_PRKCA_ST	Q9C0K0	BCL11B	P17252	PRKCA	T450	E452K	452	Missense	proximal	2	no	13.514	18.793	EPSD	TCGA;ICGC;COSMIC	16.704	Gain
AGC_PKC_PKCa_PRKCA_ST	Q9C0K0	BCL11B	P17252	PRKCA	S483	S488T	488	Missense	distal	5	no	18.915	18.739	EPSD	TCGA;COSMIC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	Q9C0K0	BCL11B	P17252	PRKCA	S483	D490N	490	Missense	distal	7	no	18.915	18.888	EPSD	TCGA;COSMIC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	Q9C0K0	BCL11B	P17252	PRKCA	S483	A481V	481	Missense	proximal	-2	no	18.915	19.158	EPSD	TCGA;COSMIC	16.704	Up-regulation
AGC_PKC_PKCa_PRKCA_ST	Q9C0K0	BCL11B	P17252	PRKCA	S483	R487H	487	Missense	distal	4	no	18.915	18.632	EPSD	TCGA;COSMIC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	Q9C0K0	BCL11B	P17252	PRKCA	S493	G491R	491	Missense	proximal	-2	no	13.977	16.849	EPSD	TCGA;ICGC;COSMIC	16.704	Gain
AGC_PKC_PKCa_PRKCA_ST	Q9C0K0	BCL11B	P17252	PRKCA	S749	G748S	748	Missense	proximal	-1	no	17.502	17.254	EPSD	TCGA;ICGC;COSMIC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	Q9C0K0	BCL11B	P17252	PRKCA	S788	R793C	793	Missense	distal	5	no	21.436	20.704	EPSD	TCGA;ICGC;COSMIC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	Q9C0K0	BCL11B	P17252	PRKCA	S789	D796N	796	Missense	distal	7	no	19.514	19.488	EPSD	TCGA;ICGC;COSMIC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	Q9C0K0	BCL11B	P17252	PRKCA	S789	R793C	793	Missense	distal	4	no	19.514	18.113	EPSD	TCGA;ICGC;COSMIC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	Q9C0K0	BCL11B	P17252	PRKCA	S795	D796N	796	Missense	proximal	1	no	16.651	17.123	EPSD	TCGA;ICGC;COSMIC	16.704	Gain
AGC_PKC_PKCa_PRKCA_ST	Q9C0K0	BCL11B	P17252	PRKCA	S795	E799K	799	Missense	distal	4	no	16.651	17.190	EPSD	TCGA;COSMIC	16.704	Gain
AGC_PKC_PKCa_PRKCA_ST	Q9C0K0	BCL11B	P17252	PRKCA	S795	T797M	797	Missense	proximal	2	no	16.651	17.013	EPSD	TCGA;COSMIC	16.704	Gain
AGC_PKC_PKCa_PRKCA_ST	Q9C0K0	BCL11B	P17252	PRKCA	S817	G820C	820	Missense	distal	3	no	21.134	19.155	EPSD	TCGA;COSMIC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	Q9C0K0	BCL11B	P17252	PRKCA	S817	R816L	816	Missense	proximal	-1	no	21.134	20.327	EPSD	TCGA;ICGC;COSMIC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	Q9C0K0	BCL11B	P17252	PRKCA	S817	R816Q	816	Missense	proximal	-1	no	21.134	20.316	EPSD	TCGA;COSMIC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	P50552	VASP	P17252	PRKCA	S157	R154C	154	Missense	distal	-3	no	18.806	16.066	PhosphoSitePlus	TCGA;ICGC;COSMIC	16.704	Loss
AGC_PKC_PKCa_PRKCA_ST	P50552	VASP	P17252	PRKCA	S239	E242D	242	Missense	distal	3	no	19.742	19.255	EPSD	TCGA;ICGC;COSMIC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	P50552	VASP	P17252	PRKCA	S255	E254K	254	Missense	proximal	-1	no	19.553	19.979	EPSD	TCGA;ICGC;COSMIC	16.704	Up-regulation
AGC_PKC_PKCa_PRKCA_ST	P50552	VASP	P17252	PRKCA	S255	G259R	259	Missense	distal	4	no	19.553	20.157	EPSD	TCGA;ICGC;COSMIC	16.704	Up-regulation
AGC_PKC_PKCa_PRKCA_ST	P50552	VASP	P17252	PRKCA	S255	S255G	255	Missense	central	0	yes	19.553	0.000	EPSD	TCGA;ICGC	16.704	Loss
AGC_PKC_PKCa_PRKCA_ST	P50552	VASP	P17252	PRKCA	S305	R298T	298	Missense	distal	-7	no	20.182	20.174	EPSD	TCGA;ICGC;COSMIC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	P50552	VASP	P17252	PRKCA	S305	W310C	310	Missense	distal	5	no	20.182	19.958	EPSD	TCGA;ICGC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	P50552	VASP	P17252	PRKCA	S305	Q302H	302	Missense	distal	-3	no	20.182	19.183	EPSD	TCGA;ICGC;COSMIC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	P50552	VASP	P17252	PRKCA	S305	R307Q	307	Missense	proximal	2	no	20.182	16.347	EPSD	TCGA;ICGC;COSMIC	16.704	Loss
AGC_PKC_PKCa_PRKCA_ST	P50552	VASP	P17252	PRKCA	S305	R307W	307	Missense	proximal	2	no	20.182	14.742	EPSD	TCGA;ICGC	16.704	Loss
AGC_PKC_PKCa_PRKCA_ST	P50552	VASP	P17252	PRKCA	S305	K312T	312	Missense	distal	7	no	20.182	20.092	EPSD	TCGA;ICGC;COSMIC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	P30411	BDKRB2	P17252	PRKCA	S12	D16N	16	Missense	distal	4	no	20.839	20.481	EPSD	TCGA;ICGC;COSMIC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	P30411	BDKRB2	P17252	PRKCA	S12	S8L	8	Missense	distal	-4	no	20.839	20.408	EPSD	TCGA;ICGC;COSMIC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	P30411	BDKRB2	P17252	PRKCA	S12	S17F	17	Missense	distal	5	no	20.839	20.873	EPSD	TCGA;ICGC;COSMIC	16.704	Up-regulation
AGC_PKC_PKCa_PRKCA_ST	Q01954	BNC1	P17252	PRKCA	S398	M394L	394	Missense	distal	-4	no	17.878	17.175	EPSD	TCGA;ICGC;COSMIC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	Q01954	BNC1	P17252	PRKCA	S398	S398F	398	Missense	central	0	yes	17.878	0.000	EPSD	TCGA;ICGC;COSMIC	16.704	Loss
AGC_PKC_PKCa_PRKCA_ST	Q01954	BNC1	P17252	PRKCA	S398	R402Q	402	Missense	distal	4	no	17.878	17.661	EPSD	TCGA;ICGC;COSMIC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	Q01954	BNC1	P17252	PRKCA	S398	R402W	402	Missense	distal	4	no	17.878	16.342	EPSD	TCGA;ICGC;COSMIC	16.704	Loss
AGC_PKC_PKCa_PRKCA_ST	Q01954	BNC1	P17252	PRKCA	S537	K536R	536	Missense	proximal	-1	no	22.040	21.983	EPSD	TCGA;ICGC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	Q01954	BNC1	P17252	PRKCA	S537	S537F	537	Missense	central	0	yes	22.040	0.000	EPSD	TCGA;ICGC;COSMIC	16.704	Loss
AGC_PKC_PKCa_PRKCA_ST	Q01954	BNC1	P17252	PRKCA	S537	P533L	533	Missense	distal	-4	no	22.040	21.781	EPSD	TCGA;ICGC;COSMIC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	Q01954	BNC1	P17252	PRKCA	S541	K536R	536	Missense	distal	-5	no	17.890	17.903	PhosphoSitePlus	TCGA;ICGC	16.704	Up-regulation
AGC_PKC_PKCa_PRKCA_ST	Q01954	BNC1	P17252	PRKCA	S541	S537F	537	Missense	distal	-4	no	17.890	17.832	PhosphoSitePlus	TCGA;ICGC;COSMIC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	Q01954	BNC1	P17252	PRKCA	S938	A945V	945	Missense	distal	7	no	17.817	17.762	EPSD	TCGA;ICGC;COSMIC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	Q01954	BNC1	P17252	PRKCA	T942	A945V	945	Missense	distal	3	no	17.837	17.581	EPSD	TCGA;ICGC;COSMIC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	Q14524	SCN5A	P17252	PRKCA	S11	R15S	15	Missense	distal	4	no	20.342	20.095	EPSD	TCGA;ICGC;COSMIC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	Q14524	SCN5A	P17252	PRKCA	S11	R8W	8	Missense	distal	-3	no	20.342	17.988	EPSD	TCGA;ICGC;COSMIC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	Q14524	SCN5A	P17252	PRKCA	S11	R14C	14	Missense	distal	3	no	20.342	17.723	EPSD	TCGA;ICGC;GDSC;CCLE	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	Q14524	SCN5A	P17252	PRKCA	S12	R15S	15	Missense	distal	3	no	24.060	22.669	EPSD	TCGA;ICGC;COSMIC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	Q14524	SCN5A	P17252	PRKCA	S12	E19Q	19	Missense	distal	7	no	24.060	24.151	EPSD	TCGA;ICGC;COSMIC	16.704	Up-regulation
AGC_PKC_PKCa_PRKCA_ST	Q14524	SCN5A	P17252	PRKCA	S12	R8W	8	Missense	distal	-4	no	24.060	23.234	EPSD	TCGA;ICGC;COSMIC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	Q14524	SCN5A	P17252	PRKCA	S12	R14C	14	Missense	proximal	2	no	24.060	19.710	EPSD	TCGA;ICGC;GDSC;CCLE	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	Q14524	SCN5A	P17252	PRKCA	T17	R15S	15	Missense	proximal	-2	no	18.215	14.913	EPSD	TCGA;ICGC;COSMIC	16.704	Loss
AGC_PKC_PKCa_PRKCA_ST	Q14524	SCN5A	P17252	PRKCA	T17	E19Q	19	Missense	proximal	2	no	18.215	20.081	EPSD	TCGA;ICGC;COSMIC	16.704	Up-regulation
AGC_PKC_PKCa_PRKCA_ST	Q14524	SCN5A	P17252	PRKCA	T17	R14C	14	Missense	distal	-3	no	18.215	15.475	EPSD	TCGA;ICGC;GDSC;CCLE	16.704	Loss
AGC_PKC_PKCa_PRKCA_ST	Q14524	SCN5A	P17252	PRKCA	S20	R27C	27	Missense	distal	7	no	16.725	16.502	EPSD	TCGA;ICGC;COSMIC	16.704	Loss
AGC_PKC_PKCa_PRKCA_ST	Q14524	SCN5A	P17252	PRKCA	S20	R15S	15	Missense	distal	-5	no	16.725	16.299	EPSD	TCGA;ICGC;COSMIC	16.704	Loss
AGC_PKC_PKCa_PRKCA_ST	Q14524	SCN5A	P17252	PRKCA	S20	E19Q	19	Missense	proximal	-1	no	16.725	16.277	EPSD	TCGA;ICGC;COSMIC	16.704	Loss
AGC_PKC_PKCa_PRKCA_ST	Q14524	SCN5A	P17252	PRKCA	S20	R27H	27	Missense	distal	7	no	16.725	16.654	EPSD	TCGA;ICGC;COSMIC	16.704	Loss
AGC_PKC_PKCa_PRKCA_ST	Q14524	SCN5A	P17252	PRKCA	S20	R14C	14	Missense	distal	-6	no	16.725	16.356	EPSD	TCGA;ICGC;GDSC;CCLE	16.704	Loss
AGC_PKC_PKCa_PRKCA_ST	Q14524	SCN5A	P17252	PRKCA	S476	K477N	477	Missense	proximal	1	no	23.937	22.772	EPSD	TCGA;ICGC;COSMIC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	Q14524	SCN5A	P17252	PRKCA	S476	R478M	478	Missense	proximal	2	no	23.937	19.489	EPSD	TCGA;ICGC;COSMIC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	Q14524	SCN5A	P17252	PRKCA	S476	S471G	471	Missense	distal	-5	no	23.937	24.073	EPSD	TCGA;ICGC;COSMIC	16.704	Up-regulation
AGC_PKC_PKCa_PRKCA_ST	Q14524	SCN5A	P17252	PRKCA	S483	K477N	477	Missense	distal	-6	no	18.998	18.874	EPSD	TCGA;ICGC;COSMIC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	Q14524	SCN5A	P17252	PRKCA	S483	R478M	478	Missense	distal	-5	no	18.998	18.832	EPSD	TCGA;ICGC;COSMIC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	Q14524	SCN5A	P17252	PRKCA	S483	E488G	488	Missense	distal	5	no	18.998	18.987	EPSD	TCGA;ICGC;COSMIC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	Q14524	SCN5A	P17252	PRKCA	S483	G485E	485	Missense	proximal	2	no	18.998	18.543	EPSD	TCGA;ICGC;COSMIC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	Q14524	SCN5A	P17252	PRKCA	S483	S484L	484	Missense	proximal	1	no	18.998	19.824	EPSD	TCGA;ICGC;COSMIC	16.704	Up-regulation
AGC_PKC_PKCa_PRKCA_ST	Q14524	SCN5A	P17252	PRKCA	S484	K477N	477	Missense	distal	-7	no	17.923	17.918	EPSD	TCGA;ICGC;COSMIC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	Q14524	SCN5A	P17252	PRKCA	S484	R478M	478	Missense	distal	-6	no	17.923	17.847	EPSD	TCGA;ICGC;COSMIC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	Q14524	SCN5A	P17252	PRKCA	S484	E488G	488	Missense	distal	4	no	17.923	17.687	EPSD	TCGA;ICGC;COSMIC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	Q14524	SCN5A	P17252	PRKCA	S484	G485E	485	Missense	proximal	1	no	17.923	17.309	EPSD	TCGA;ICGC;COSMIC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	Q14524	SCN5A	P17252	PRKCA	S484	S484L	484	Missense	central	0	yes	17.923	0.000	EPSD	TCGA;ICGC;COSMIC	16.704	Loss
AGC_PKC_PKCa_PRKCA_ST	Q14524	SCN5A	P17252	PRKCA	S519	R523H	523	Missense	distal	4	no	21.739	21.456	EPSD	TCGA;ICGC;COSMIC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	Q14524	SCN5A	P17252	PRKCA	S519	R513H	513	Missense	distal	-6	no	21.739	21.671	EPSD	TCGA;ICGC;COSMIC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	Q14524	SCN5A	P17252	PRKCA	S524	R523H	523	Missense	proximal	-1	no	21.073	20.750	EPSD	TCGA;ICGC;COSMIC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	Q14524	SCN5A	P17252	PRKCA	S525	R523H	523	Missense	proximal	-2	no	17.417	12.864	EPSD	TCGA;ICGC;COSMIC	16.704	Loss
AGC_PKC_PKCa_PRKCA_ST	Q14524	SCN5A	P17252	PRKCA	S528	R523H	523	Missense	distal	-5	no	19.052	18.697	EPSD	TCGA;ICGC;COSMIC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	Q14524	SCN5A	P17252	PRKCA	S528	R534W	534	Missense	distal	6	no	19.052	18.805	EPSD	TCGA;ICGC;COSMIC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	Q14524	SCN5A	P17252	PRKCA	S528	R535Q	535	Missense	distal	7	no	19.052	19.048	EPSD	TCGA;ICGC;COSMIC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	Q14524	SCN5A	P17252	PRKCA	S528	R533C	533	Missense	distal	5	no	19.052	18.321	EPSD	TCGA;ICGC;COSMIC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	Q14524	SCN5A	P17252	PRKCA	T531	R534W	534	Missense	distal	3	no	20.137	17.203	EPSD	TCGA;ICGC;COSMIC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	Q14524	SCN5A	P17252	PRKCA	T531	R535Q	535	Missense	distal	4	no	20.137	19.919	EPSD	TCGA;ICGC;COSMIC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	Q14524	SCN5A	P17252	PRKCA	T531	R533C	533	Missense	proximal	2	no	20.137	15.786	EPSD	TCGA;ICGC;COSMIC	16.704	Loss
AGC_PKC_PKCa_PRKCA_ST	Q14524	SCN5A	P17252	PRKCA	S571	R568C	568	Missense	distal	-3	no	22.789	20.049	EPSD	TCGA;ICGC;COSMIC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	Q14524	SCN5A	P17252	PRKCA	S571	G574E	574	Missense	distal	3	no	22.789	22.190	EPSD	TCGA;ICGC;COSMIC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	Q14524	SCN5A	P17252	PRKCA	S571	P578L	578	Missense	distal	7	no	22.789	22.755	EPSD	TCGA;ICGC;COSMIC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	Q14524	SCN5A	P17252	PRKCA	S581	A582D	582	Missense	proximal	1	no	16.895	15.672	EPSD	TCGA;ICGC;COSMIC	16.704	Loss
AGC_PKC_PKCa_PRKCA_ST	Q14524	SCN5A	P17252	PRKCA	S581	S581L	581	Missense	central	0	yes	16.895	0.000	EPSD	TCGA;ICGC;COSMIC;GDSC;CCLE	16.704	Loss
AGC_PKC_PKCa_PRKCA_ST	Q14524	SCN5A	P17252	PRKCA	S581	T580P	580	Missense	proximal	-1	no	16.895	16.974	EPSD	TCGA	16.704	Up-regulation
AGC_PKC_PKCa_PRKCA_ST	Q14524	SCN5A	P17252	PRKCA	S581	G584D	584	Missense	distal	3	no	16.895	15.810	EPSD	TCGA;ICGC;COSMIC	16.704	Loss
AGC_PKC_PKCa_PRKCA_ST	Q14524	SCN5A	P17252	PRKCA	S581	G574E	574	Missense	distal	-7	no	16.895	16.892	EPSD	TCGA;ICGC;COSMIC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	Q14524	SCN5A	P17252	PRKCA	S581	P578L	578	Missense	distal	-3	no	16.895	16.388	EPSD	TCGA;ICGC;COSMIC	16.704	Loss
AGC_PKC_PKCa_PRKCA_ST	Q14524	SCN5A	P17252	PRKCA	S1079	Q1077R	1077	Missense	proximal	-2	no	16.643	18.402	EPSD	TCGA;COSMIC	16.704	Gain
AGC_PKC_PKCa_PRKCA_ST	Q14524	SCN5A	P17252	PRKCA	S1079	V1082G	1082	Missense	distal	3	no	16.643	17.857	EPSD	TCGA;COSMIC	16.704	Gain
AGC_PKC_PKCa_PRKCA_ST	Q14524	SCN5A	P17252	PRKCA	S1079	P1081L	1081	Missense	proximal	2	no	16.643	16.859	EPSD	TCGA;COSMIC	16.704	Gain
AGC_PKC_PKCa_PRKCA_ST	Q14524	SCN5A	P17252	PRKCA	S1079	E1078K	1078	Missense	proximal	-1	no	16.643	17.069	EPSD	TCGA;COSMIC	16.704	Gain
AGC_PKC_PKCa_PRKCA_ST	Q14524	SCN5A	P17252	PRKCA	S1079	P1081A	1081	Missense	proximal	2	no	16.643	17.147	EPSD	TCGA;COSMIC	16.704	Gain
AGC_PKC_PKCa_PRKCA_ST	Q14524	SCN5A	P17252	PRKCA	S1503	P1509L	1509	Missense	distal	6	no	21.117	21.073	PhosphoSitePlus	TCGA;COSMIC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	Q14524	SCN5A	P17252	PRKCA	S1503	K1500T	1500	Missense	distal	-3	no	21.117	18.980	PhosphoSitePlus	TCGA;COSMIC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	Q14524	SCN5A	P17252	PRKCA	T1895	R1897Q	1897	Missense	proximal	2	no	17.236	13.402	EPSD	TCGA;COSMIC	16.704	Loss
AGC_PKC_PKCa_PRKCA_ST	Q14524	SCN5A	P17252	PRKCA	T1895	R1898C	1898	Missense	distal	3	no	17.236	14.618	EPSD	TCGA;COSMIC	16.704	Loss
AGC_PKC_PKCa_PRKCA_ST	Q14524	SCN5A	P17252	PRKCA	T1895	E1901K	1901	Missense	distal	6	no	17.236	17.330	EPSD	TCGA;COSMIC	16.704	Up-regulation
AGC_PKC_PKCa_PRKCA_ST	Q14524	SCN5A	P17252	PRKCA	T1895	S1888F	1888	Missense	distal	-7	no	17.236	17.228	EPSD	TCGA;COSMIC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	Q14524	SCN5A	P17252	PRKCA	S1920	R1919C	1919	Missense	proximal	-1	no	20.164	17.504	EPSD	TCGA;COSMIC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	Q9HAN9	NMNAT1	P17252	PRKCA	S136	Q137E	137	Missense	proximal	1	no	19.786	18.336	PhosphoSitePlus	TCGA;ICGC;COSMIC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	Q9HAN9	NMNAT1	P17252	PRKCA	S136	S135C	135	Missense	proximal	-1	no	19.786	17.513	PhosphoSitePlus	TCGA;ICGC;COSMIC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	Q9HAN9	NMNAT1	P17252	PRKCA	S136	K138N	138	Missense	proximal	2	no	19.786	14.837	PhosphoSitePlus	TCGA;ICGC;COSMIC	16.704	Loss
AGC_PKC_PKCa_PRKCA_ST	P35900	KRT20	P17252	PRKCA	S13	V20L	20	Missense	distal	7	no	18.842	18.901	PhosphoSitePlus	TCGA;ICGC;COSMIC	16.704	Up-regulation
AGC_PKC_PKCa_PRKCA_ST	P35900	KRT20	P17252	PRKCA	S14	V20L	20	Missense	distal	6	no	16.717	16.795	EPSD	TCGA;ICGC;COSMIC	16.704	Up-regulation
AGC_PKC_PKCa_PRKCA_ST	P35900	KRT20	P17252	PRKCA	S83	L85Q	85	Missense	proximal	2	no	18.907	20.060	EPSD	TCGA;ICGC;COSMIC	16.704	Up-regulation
AGC_PKC_PKCa_PRKCA_ST	P35900	KRT20	P17252	PRKCA	S118	I124T	124	Missense	distal	6	no	16.820	16.806	EPSD	TCGA;ICGC;COSMIC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	P35900	KRT20	P17252	PRKCA	S118	E125K	125	Missense	distal	7	no	16.820	16.966	EPSD	TCGA;ICGC;COSMIC	16.704	Up-regulation
AGC_PKC_PKCa_PRKCA_ST	P35900	KRT20	P17252	PRKCA	S118	R115H	115	Missense	distal	-3	no	16.820	12.964	EPSD	TCGA;ICGC	16.704	Loss
AGC_PKC_PKCa_PRKCA_ST	P35900	KRT20	P17252	PRKCA	S293	T292N	292	Missense	proximal	-1	no	18.661	18.881	EPSD	TCGA;ICGC;COSMIC	16.704	Up-regulation
AGC_PKC_PKCa_PRKCA_ST	P35900	KRT20	P17252	PRKCA	S293	R291C	291	Missense	proximal	-2	no	18.661	16.961	EPSD	TCGA;ICGC;COSMIC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	P35900	KRT20	P17252	PRKCA	S293	E288K	288	Missense	distal	-5	no	18.661	18.955	EPSD	TCGA;ICGC	16.704	Up-regulation
AGC_PKC_PKCa_PRKCA_ST	Q71U36	TUBA1A	P17252	PRKCA	T82	H88N	88	Missense	distal	6	no	19.353	19.257	EPSD	TCGA;ICGC;COSMIC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	Q71U36	TUBA1A	P17252	PRKCA	T82	R84H	84	Missense	proximal	2	no	19.353	14.330	EPSD	TCGA	16.704	Loss
AGC_PKC_PKCa_PRKCA_ST	Q71U36	TUBA1A	P17252	PRKCA	T82	Q85H	85	Missense	distal	3	no	19.353	21.094	EPSD	TCGA	16.704	Up-regulation
AGC_PKC_PKCa_PRKCA_ST	Q71U36	TUBA1A	P17252	PRKCA	S158	R156C	156	Missense	proximal	-2	no	16.944	15.244	EPSD	TCGA;ICGC	16.704	Loss
AGC_PKC_PKCa_PRKCA_ST	Q71U36	TUBA1A	P17252	PRKCA	S158	K164T	164	Missense	distal	6	no	16.944	16.837	EPSD	TCGA;COSMIC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	Q71U36	TUBA1A	P17252	PRKCA	S158	R156H	156	Missense	proximal	-2	no	16.944	12.391	EPSD	TCGA;COSMIC	16.704	Loss
AGC_PKC_PKCa_PRKCA_ST	Q71U36	TUBA1A	P17252	PRKCA	S158	S165C	165	Missense	distal	7	no	16.944	16.767	EPSD	TCGA;COSMIC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	Q71U36	TUBA1A	P17252	PRKCA	S158	G162D	162	Missense	distal	4	no	16.944	16.949	EPSD	TCGA;COSMIC	16.704	Up-regulation
AGC_PKC_PKCa_PRKCA_ST	Q71U36	TUBA1A	P17252	PRKCA	S165	K164T	164	Missense	proximal	-1	no	17.652	16.830	PhosphoSitePlus	TCGA;COSMIC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	Q71U36	TUBA1A	P17252	PRKCA	S165	S165C	165	Missense	central	0	yes	17.652	0.000	PhosphoSitePlus	TCGA;COSMIC	16.704	Loss
AGC_PKC_PKCa_PRKCA_ST	Q71U36	TUBA1A	P17252	PRKCA	S165	G162D	162	Missense	distal	-3	no	17.652	15.872	PhosphoSitePlus	TCGA;COSMIC	16.704	Loss
AGC_PKC_PKCa_PRKCA_ST	Q15762	CD226	P17252	PRKCA	S329	R330H	330	Missense	proximal	1	no	16.809	15.996	PhosphoSitePlus	TCGA;ICGC;COSMIC;GDSC	16.704	Loss
AGC_PKC_PKCa_PRKCA_ST	Q15762	CD226	P17252	PRKCA	S329	V323A	323	Missense	distal	-6	no	16.809	16.886	PhosphoSitePlus	TCGA	16.704	Up-regulation
AGC_PKC_PKCa_PRKCA_ST	P14416	DRD2	P17252	PRKCA	S147	N143T	143	Missense	distal	-4	no	22.313	21.981	EPSD	TCGA;ICGC;COSMIC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	P14416	DRD2	P17252	PRKCA	S147	S148F	148	Missense	proximal	1	no	22.313	23.796	EPSD	TCGA;ICGC;COSMIC	16.704	Up-regulation
AGC_PKC_PKCa_PRKCA_ST	P14416	DRD2	P17252	PRKCA	S147	T144M	144	Missense	distal	-3	no	22.313	23.504	EPSD	TCGA;ICGC;COSMIC	16.704	Up-regulation
AGC_PKC_PKCa_PRKCA_ST	P14416	DRD2	P17252	PRKCA	S148	M155I	155	Missense	distal	7	no	22.832	22.668	EPSD	TCGA;ICGC;COSMIC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	P14416	DRD2	P17252	PRKCA	S148	N143T	143	Missense	distal	-5	no	22.832	23.089	EPSD	TCGA;ICGC;COSMIC	16.704	Up-regulation
AGC_PKC_PKCa_PRKCA_ST	P14416	DRD2	P17252	PRKCA	S148	S148F	148	Missense	central	0	yes	22.832	0.000	EPSD	TCGA;ICGC;COSMIC	16.704	Loss
AGC_PKC_PKCa_PRKCA_ST	P14416	DRD2	P17252	PRKCA	S148	T144M	144	Missense	distal	-4	no	22.832	23.766	EPSD	TCGA;ICGC;COSMIC	16.704	Up-regulation
AGC_PKC_PKCa_PRKCA_ST	P14416	DRD2	P17252	PRKCA	T225	R219H	219	Missense	distal	-6	no	21.887	21.819	EPSD	TCGA;ICGC;COSMIC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	P14416	DRD2	P17252	PRKCA	T225	R219C	219	Missense	distal	-6	no	21.887	21.517	EPSD	TCGA;ICGC;COSMIC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	P14416	DRD2	P17252	PRKCA	T225	R222Q	222	Missense	distal	-3	no	21.887	19.029	EPSD	TCGA;ICGC;COSMIC;CCLE	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	P14416	DRD2	P17252	PRKCA	T225	S228N	228	Missense	distal	3	no	21.887	21.708	EPSD	TCGA;ICGC;COSMIC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	P14416	DRD2	P17252	PRKCA	S228	R233K	233	Missense	distal	5	no	18.941	19.084	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	16.704	Up-regulation
AGC_PKC_PKCa_PRKCA_ST	P14416	DRD2	P17252	PRKCA	S228	R222Q	222	Missense	distal	-6	no	18.941	18.798	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC;CCLE	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	P14416	DRD2	P17252	PRKCA	S228	S228N	228	Missense	central	0	yes	18.941	0.000	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	16.704	Loss
AGC_PKC_PKCa_PRKCA_ST	P14416	DRD2	P17252	PRKCA	S228	R233S	233	Missense	distal	5	no	18.941	18.799	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	P14416	DRD2	P17252	PRKCA	S229	R233K	233	Missense	distal	4	no	17.910	18.081	PhosphoSitePlus;EPSD	TCGA;ICGC;COSMIC	16.704	Up-regulation
AGC_PKC_PKCa_PRKCA_ST	P14416	DRD2	P17252	PRKCA	S229	R222Q	222	Missense	distal	-7	no	17.910	17.902	PhosphoSitePlus;EPSD	TCGA;ICGC;COSMIC;CCLE	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	P14416	DRD2	P17252	PRKCA	S229	S228N	228	Missense	proximal	-1	no	17.910	17.752	PhosphoSitePlus;EPSD	TCGA;ICGC;COSMIC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	P14416	DRD2	P17252	PRKCA	S229	R233S	233	Missense	distal	4	no	17.910	17.664	PhosphoSitePlus;EPSD	TCGA;ICGC;COSMIC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	P14416	DRD2	P17252	PRKCA	S354	K356R	356	Missense	proximal	2	no	21.245	21.666	EPSD	TCGA;ICGC;COSMIC	16.704	Up-regulation
AGC_PKC_PKCa_PRKCA_ST	P14416	DRD2	P17252	PRKCA	S354	R352W	352	Missense	proximal	-2	no	21.245	19.247	EPSD	TCGA;ICGC;COSMIC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	P14416	DRD2	P17252	PRKCA	S354	P347L	347	Missense	distal	-7	no	21.245	21.242	EPSD	TCGA;ICGC;COSMIC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	P14416	DRD2	P17252	PRKCA	S359	K356R	356	Missense	distal	-3	no	22.387	24.413	EPSD	TCGA;ICGC;COSMIC	16.704	Up-regulation
AGC_PKC_PKCa_PRKCA_ST	P14416	DRD2	P17252	PRKCA	S359	R352W	352	Missense	distal	-7	no	22.387	22.370	EPSD	TCGA;ICGC;COSMIC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	P14416	DRD2	P17252	PRKCA	S359	L363H	363	Missense	distal	4	no	22.387	23.143	EPSD	TCGA;ICGC;COSMIC	16.704	Up-regulation
AGC_PKC_PKCa_PRKCA_ST	P14416	DRD2	P17252	PRKCA	S359	S364F	364	Missense	distal	5	no	22.387	22.421	EPSD	TCGA;ICGC;COSMIC	16.704	Up-regulation
AGC_PKC_PKCa_PRKCA_ST	P49685	GPR15	P17252	PRKCA	S329	E331K	331	Missense	proximal	2	no	12.550	17.829	EPSD	TCGA;ICGC;COSMIC	16.704	Gain
AGC_PKC_PKCa_PRKCA_ST	P49685	GPR15	P17252	PRKCA	S357	R353S	353	Missense	distal	-4	no	17.197	17.004	PhosphoSitePlus	TCGA;ICGC;COSMIC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	Q96QS3	ARX	P17252	PRKCA	S18	E12K	12	Missense	distal	-6	no	16.912	16.979	EPSD	TCGA;ICGC;COSMIC	16.704	Up-regulation
AGC_PKC_PKCa_PRKCA_ST	Q96QS3	ARX	P17252	PRKCA	S18	L24R	24	Missense	distal	6	no	16.912	16.994	EPSD	TCGA;ICGC;COSMIC	16.704	Up-regulation
AGC_PKC_PKCa_PRKCA_ST	Q96QS3	ARX	P17252	PRKCA	S18	L23F	23	Missense	distal	5	no	16.912	17.137	EPSD	TCGA;ICGC;COSMIC	16.704	Up-regulation
AGC_PKC_PKCa_PRKCA_ST	Q96QS3	ARX	P17252	PRKCA	T22	L24R	24	Missense	proximal	2	no	14.387	19.373	EPSD	TCGA;ICGC;COSMIC	16.704	Gain
AGC_PKC_PKCa_PRKCA_ST	Q96QS3	ARX	P17252	PRKCA	S37	G34R	34	Missense	distal	-3	no	17.590	20.852	EPSD	TCGA;ICGC;COSMIC	16.704	Up-regulation
AGC_PKC_PKCa_PRKCA_ST	Q96QS3	ARX	P17252	PRKCA	S37	R35Q	35	Missense	proximal	-2	no	17.590	15.832	EPSD	TCGA;ICGC;COSMIC	16.704	Loss
AGC_PKC_PKCa_PRKCA_ST	Q96QS3	ARX	P17252	PRKCA	S37	R42W	42	Missense	distal	5	no	17.590	17.083	EPSD	TCGA;ICGC;COSMIC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	Q96QS3	ARX	P17252	PRKCA	S67	E61K	61	Missense	distal	-6	no	20.150	20.218	EPSD	TCGA;ICGC;COSMIC	16.704	Up-regulation
AGC_PKC_PKCa_PRKCA_ST	Q96QS3	ARX	P17252	PRKCA	S530	A534V	534	Missense	distal	4	no	19.562	18.225	EPSD	TCGA;ICGC;COSMIC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	Q96QS3	ARX	P17252	PRKCA	S531	A534V	534	Missense	distal	3	no	17.351	17.094	EPSD	TCGA;ICGC;COSMIC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	P08581	MET	P17252	PRKCA	T1257	S1254R	1254	Missense	distal	-3	no	14.897	17.767	EPSD	TCGA;COSMIC	16.704	Gain
AGC_PKC_PKCa_PRKCA_ST	P22460	KCNA5	P17252	PRKCA	S414	L413I	413	Missense	proximal	-1	no	17.936	17.072	EPSD	TCGA;ICGC;COSMIC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	P22460	KCNA5	P17252	PRKCA	S414	R409H	409	Missense	distal	-5	no	17.936	17.581	EPSD	TCGA;ICGC;COSMIC;CCLE	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	P22460	KCNA5	P17252	PRKCA	S414	R415C	415	Missense	proximal	1	no	17.936	15.100	EPSD	TCGA;ICGC;COSMIC	16.704	Loss
AGC_PKC_PKCa_PRKCA_ST	P22460	KCNA5	P17252	PRKCA	S414	R415H	415	Missense	proximal	1	no	17.936	17.123	EPSD	TCGA;ICGC;COSMIC;CCLE	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	P22460	KCNA5	P17252	PRKCA	S417	L413I	413	Missense	distal	-4	no	17.099	17.088	EPSD	TCGA;ICGC;COSMIC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	P22460	KCNA5	P17252	PRKCA	S417	R415C	415	Missense	proximal	-2	no	17.099	15.399	EPSD	TCGA;ICGC;COSMIC	16.704	Loss
AGC_PKC_PKCa_PRKCA_ST	P22460	KCNA5	P17252	PRKCA	S417	R415H	415	Missense	proximal	-2	no	17.099	12.545	EPSD	TCGA;ICGC;COSMIC;CCLE	16.704	Loss
AGC_PKC_PKCa_PRKCA_ST	P22460	KCNA5	P17252	PRKCA	S430	L434Q	434	Missense	distal	4	no	17.446	18.267	EPSD	TCGA;ICGC;COSMIC	16.704	Up-regulation
AGC_PKC_PKCa_PRKCA_ST	P22460	KCNA5	P17252	PRKCA	S430	K425N	425	Missense	distal	-5	no	17.446	17.103	EPSD	TCGA;ICGC;COSMIC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	P22460	KCNA5	P17252	PRKCA	S430	L427S	427	Missense	distal	-3	no	17.446	18.932	EPSD	TCGA;ICGC;COSMIC	16.704	Up-regulation
AGC_PKC_PKCa_PRKCA_ST	P22460	KCNA5	P17252	PRKCA	S430	L436M	436	Missense	distal	6	no	17.446	17.456	EPSD	TCGA;ICGC;COSMIC	16.704	Up-regulation
AGC_PKC_PKCa_PRKCA_ST	P22460	KCNA5	P17252	PRKCA	S430	G435E	435	Missense	distal	5	no	17.446	17.458	EPSD	TCGA;ICGC;COSMIC	16.704	Up-regulation
AGC_PKC_PKCa_PRKCA_ST	P22460	KCNA5	P17252	PRKCA	S557	R550T	550	Missense	distal	-7	no	17.842	17.835	EPSD	TCGA;ICGC;COSMIC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	P22460	KCNA5	P17252	PRKCA	S557	S562F	562	Missense	distal	5	no	17.842	17.877	EPSD	TCGA;ICGC;COSMIC	16.704	Up-regulation
AGC_PKC_PKCa_PRKCA_ST	P22460	KCNA5	P17252	PRKCA	S557	G558R	558	Missense	proximal	1	no	17.842	18.796	EPSD	TCGA;ICGC	16.704	Up-regulation
AGC_PKC_PKCa_PRKCA_ST	P22460	KCNA5	P17252	PRKCA	S557	G561E	561	Missense	distal	4	no	17.842	18.078	EPSD	TCGA;ICGC;COSMIC	16.704	Up-regulation
AGC_PKC_PKCa_PRKCA_ST	P22460	KCNA5	P17252	PRKCA	S557	R554Q	554	Missense	distal	-3	no	17.842	14.985	EPSD	TCGA;ICGC;COSMIC	16.704	Loss
AGC_PKC_PKCa_PRKCA_ST	P22460	KCNA5	P17252	PRKCA	S575	R577Q	577	Missense	proximal	2	no	18.442	14.607	EPSD	TCGA;ICGC;COSMIC;GDSC;CCLE	16.704	Loss
AGC_PKC_PKCa_PRKCA_ST	P22460	KCNA5	P17252	PRKCA	S575	P582L	582	Missense	distal	7	no	18.442	18.408	EPSD	TCGA;ICGC;COSMIC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	P22460	KCNA5	P17252	PRKCA	S575	G579S	579	Missense	distal	4	no	18.442	18.799	EPSD	TCGA;ICGC;COSMIC	16.704	Up-regulation
AGC_PKC_PKCa_PRKCA_ST	Q06481	APLP2	P17252	PRKCA	T723	I724M	724	Missense	proximal	1	no	16.878	15.827	PhosphoSitePlus	TCGA	16.704	Loss
AGC_PKC_PKCa_PRKCA_ST	Q06481	APLP2	P17252	PRKCA	T723	R717M	717	Missense	distal	-6	no	16.878	16.802	PhosphoSitePlus	TCGA;COSMIC	16.704	Down-regulation
TK_Src_SRM_Y	Q13882	PTK6	Q9H3Y6	SRMS	Y13	G10D	10	Missense	distal	-3	no	1.093	1.239	EPSD	TCGA;ICGC	1.179	Gain
TK_Src_SRM_Y	Q13882	PTK6	Q9H3Y6	SRMS	Y61	G54D	54	Missense	distal	-7	no	1.564	1.615	EPSD	TCGA;ICGC;COSMIC	1.179	Up-regulation
TK_Src_SRM_Y	Q13882	PTK6	Q9H3Y6	SRMS	Y61	G60V	60	Missense	proximal	-1	no	1.564	1.575	EPSD	TCGA;ICGC;COSMIC	1.179	Up-regulation
TK_Src_SRM_Y	Q13882	PTK6	Q9H3Y6	SRMS	Y66	G60V	60	Missense	distal	-6	no	2.496	2.485	EPSD	TCGA;ICGC;COSMIC	1.179	Down-regulation
TK_Src_SRM_Y	Q13882	PTK6	Q9H3Y6	SRMS	Y447	E448K	448	Missense	proximal	1	no	3.022	2.989	PhosphoSitePlus	TCGA;ICGC	1.179	Down-regulation
CAMK_CAMKL_BRSK_BRSK1_ST	P23258	TUBG1	Q8TDC3	BRSK1	S131	V136L	136	Missense	distal	5	no	1.301	1.351	PhosphoSitePlus;EPSD	TCGA;ICGC;COSMIC	0.579	Up-regulation
CAMK_CAMKL_BRSK_BRSK1_ST	P23258	TUBG1	Q8TDC3	BRSK1	S131	E133Q	133	Missense	proximal	2	no	1.301	1.297	PhosphoSitePlus;EPSD	TCGA;ICGC;COSMIC	0.579	Down-regulation
CAMK_CAMKL_BRSK_BRSK1_ST	P23258	TUBG1	Q8TDC3	BRSK1	S306	R311C	311	Missense	distal	5	no	0.575	0.586	EPSD	TCGA;ICGC;COSMIC	0.579	Gain
CAMK_CAMKL_BRSK_BRSK1_ST	P23258	TUBG1	Q8TDC3	BRSK1	S336	R343C	343	Missense	distal	7	no	0.658	0.676	EPSD	TCGA;ICGC;COSMIC	0.579	Up-regulation
CAMK_CAMKL_BRSK_BRSK1_ST	P23258	TUBG1	Q8TDC3	BRSK1	S336	S336N	336	Missense	central	0	yes	0.658	0.000	EPSD	TCGA;ICGC;COSMIC	0.579	Loss
CAMK_CAMKL_BRSK_BRSK1_ST	P23258	TUBG1	Q8TDC3	BRSK1	S336	Q338H	338	Missense	proximal	2	no	0.658	0.659	EPSD	TCGA;ICGC;COSMIC	0.579	Up-regulation
CAMK_CAMKL_BRSK_BRSK1_ST	P23258	TUBG1	Q8TDC3	BRSK1	S385	E389K	389	Missense	distal	4	no	1.207	1.217	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	0.579	Up-regulation
Other_IKK_IKBKB_ST	Q9NQC7	CYLD	O14920	IKBKB	S111	K114T	114	Missense	distal	3	no	21.767	22.042	EPSD	TCGA;ICGC;COSMIC	16.613	Up-regulation
Other_IKK_IKBKB_ST	Q9NQC7	CYLD	O14920	IKBKB	S111	F110L	110	Missense	proximal	-1	no	21.767	21.158	EPSD	TCGA;ICGC;COSMIC	16.613	Down-regulation
Other_IKK_IKBKB_ST	Q9NQC7	CYLD	O14920	IKBKB	S362	G360V	360	Missense	proximal	-2	no	17.645	16.476	EPSD	TCGA;ICGC;COSMIC	16.613	Loss
Other_IKK_IKBKB_ST	Q9NQC7	CYLD	O14920	IKBKB	S418	N414H	414	Missense	distal	-4	no	21.328	23.026	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	16.613	Up-regulation
Other_IKK_IKBKB_ST	Q9NQC7	CYLD	O14920	IKBKB	S418	E413D	413	Missense	distal	-5	no	21.328	21.323	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	16.613	Down-regulation
Other_IKK_IKBKB_ST	Q9NQC7	CYLD	O14920	IKBKB	S418	K425E	425	Missense	distal	7	no	21.328	21.625	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	16.613	Up-regulation
Other_IKK_IKBKB_ST	Q9NQC7	CYLD	O14920	IKBKB	S422	K425E	425	Missense	distal	3	no	21.385	22.413	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	16.613	Up-regulation
Other_IKK_IKBKB_ST	Q9NQC7	CYLD	O14920	IKBKB	S422	N428D	428	Missense	distal	6	no	21.385	20.740	EPSD;PhosphoSitePlus	TCGA;ICGC	16.613	Down-regulation
Other_IKK_IKBKB_ST	Q9NQC7	CYLD	O14920	IKBKB	S422	S418T	418	Missense	distal	-4	no	21.385	17.684	EPSD;PhosphoSitePlus	TCGA;ICGC	16.613	Down-regulation
Other_IKK_IKBKB_ST	Q9NQC7	CYLD	O14920	IKBKB	S432	K425E	425	Missense	distal	-7	no	20.183	20.737	PhosphoSitePlus;EPSD	TCGA;ICGC;COSMIC	16.613	Up-regulation
Other_IKK_IKBKB_ST	Q9NQC7	CYLD	O14920	IKBKB	S432	N428D	428	Missense	distal	-4	no	20.183	23.984	PhosphoSitePlus;EPSD	TCGA;ICGC	16.613	Up-regulation
Other_IKK_IKBKB_ST	Q9NQC7	CYLD	O14920	IKBKB	S441	E447D	447	Missense	distal	6	no	20.238	19.576	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	16.613	Down-regulation
Other_IKK_IKBKB_ST	Q9NQC7	CYLD	O14920	IKBKB	S444	E447D	447	Missense	distal	3	no	20.149	19.518	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	16.613	Down-regulation
Other_IKK_IKBKB_ST	Q99704	DOK1	O14920	IKBKB	S192	L185F	185	Missense	distal	-7	no	19.117	18.233	EPSD	TCGA;ICGC;COSMIC	16.613	Down-regulation
Other_IKK_IKBKB_ST	Q99704	DOK1	O14920	IKBKB	S281	G284D	284	Missense	distal	3	no	17.935	18.298	EPSD	TCGA;ICGC;COSMIC	16.613	Up-regulation
Other_IKK_IKBKB_ST	Q99704	DOK1	O14920	IKBKB	S302	A306V	306	Missense	distal	4	no	20.031	17.341	EPSD	TCGA	16.613	Down-regulation
Other_IKK_IKBKB_ST	Q99704	DOK1	O14920	IKBKB	S313	S310F	310	Missense	distal	-3	no	18.244	17.500	EPSD	TCGA;COSMIC	16.613	Down-regulation
Other_IKK_IKBKB_ST	Q99704	DOK1	O14920	IKBKB	S313	A306V	306	Missense	distal	-7	no	18.244	15.112	EPSD	TCGA	16.613	Loss
Other_IKK_IKBKB_ST	Q99704	DOK1	O14920	IKBKB	S313	D317N	317	Missense	distal	4	no	18.244	18.229	EPSD	TCGA;COSMIC	16.613	Down-regulation
Other_IKK_IKBKB_ST	Q99704	DOK1	O14920	IKBKB	S313	P318S	318	Missense	distal	5	no	18.244	18.445	EPSD	TCGA;ICGC	16.613	Up-regulation
Other_IKK_IKBKB_ST	Q99704	DOK1	O14920	IKBKB	S321	A324G	324	Missense	distal	3	no	17.906	18.114	EPSD	TCGA;COSMIC	16.613	Up-regulation
Other_IKK_IKBKB_ST	Q99704	DOK1	O14920	IKBKB	S321	D317N	317	Missense	distal	-4	no	17.906	14.104	EPSD	TCGA;COSMIC	16.613	Loss
Other_IKK_IKBKB_ST	Q99704	DOK1	O14920	IKBKB	S321	P318S	318	Missense	distal	-3	no	17.906	18.453	EPSD	TCGA;ICGC	16.613	Up-regulation
Other_IKK_IKBKB_ST	Q99704	DOK1	O14920	IKBKB	S439	A436T	436	Missense	distal	-3	no	17.216	17.164	EPSD;PhosphoSitePlus	TCGA;COSMIC	16.613	Down-regulation
Other_IKK_IKBKB_ST	Q99704	DOK1	O14920	IKBKB	S439	T435I	435	Missense	distal	-4	no	17.216	13.797	EPSD;PhosphoSitePlus	TCGA;COSMIC	16.613	Loss
Other_IKK_IKBKB_ST	Q99704	DOK1	O14920	IKBKB	S443	A436T	436	Missense	distal	-7	no	27.181	26.750	EPSD;PhosphoSitePlus	TCGA;COSMIC	16.613	Down-regulation
Other_IKK_IKBKB_ST	Q99704	DOK1	O14920	IKBKB	S455	S460I	460	Missense	distal	5	no	25.294	22.942	EPSD	TCGA;COSMIC	16.613	Down-regulation
Other_IKK_IKBKB_ST	Q99704	DOK1	O14920	IKBKB	S455	D462N	462	Missense	distal	7	no	25.294	25.309	EPSD	TCGA;COSMIC	16.613	Up-regulation
Other_IKK_IKBKB_ST	Q99704	DOK1	O14920	IKBKB	S466	S460I	460	Missense	distal	-6	no	18.191	16.980	EPSD	TCGA;COSMIC	16.613	Down-regulation
Other_IKK_IKBKB_ST	Q99704	DOK1	O14920	IKBKB	S466	R467K	467	Missense	proximal	1	no	18.191	16.349	EPSD	TCGA;ICGC;COSMIC	16.613	Loss
Other_IKK_IKBKB_ST	Q99704	DOK1	O14920	IKBKB	S466	D462N	462	Missense	distal	-4	no	18.191	14.389	EPSD	TCGA;COSMIC	16.613	Loss
Other_IKK_IKBKB_ST	Q04206	RELA	O14920	IKBKB	S45	E39K	39	Missense	distal	-6	no	17.029	16.852	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	16.613	Down-regulation
Other_IKK_IKBKB_ST	Q04206	RELA	O14920	IKBKB	S45	E49K	49	Missense	distal	4	no	17.029	14.170	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	16.613	Loss
Other_IKK_IKBKB_ST	Q04206	RELA	O14920	IKBKB	S45	G44V	44	Missense	proximal	-1	no	17.029	16.900	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	16.613	Down-regulation
Other_IKK_IKBKB_ST	Q04206	RELA	O14920	IKBKB	S112	R108C	108	Missense	distal	-4	no	18.249	14.862	EPSD	TCGA;ICGC;COSMIC	16.613	Loss
Other_IKK_IKBKB_ST	Q04206	RELA	O14920	IKBKB	S112	R108H	108	Missense	distal	-4	no	18.249	18.553	EPSD	TCGA;ICGC	16.613	Up-regulation
Other_IKK_IKBKB_ST	Q04206	RELA	O14920	IKBKB	S131	R133H	133	Missense	proximal	2	no	21.693	21.671	PhosphoSitePlus;EPSD	TCGA;ICGC;COSMIC	16.613	Down-regulation
Other_IKK_IKBKB_ST	Q04206	RELA	O14920	IKBKB	S131	E127K	127	Missense	distal	-4	no	21.693	19.235	PhosphoSitePlus;EPSD	TCGA;ICGC;COSMIC	16.613	Down-regulation
Other_IKK_IKBKB_ST	Q04206	RELA	O14920	IKBKB	S261	P256S	256	Missense	distal	-5	no	17.978	17.945	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	16.613	Down-regulation
Other_IKK_IKBKB_ST	Q04206	RELA	O14920	IKBKB	S261	P256L	256	Missense	distal	-5	no	17.978	17.889	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	16.613	Down-regulation
Other_IKK_IKBKB_ST	Q04206	RELA	O14920	IKBKB	S261	A258V	258	Missense	distal	-3	no	17.978	17.519	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	16.613	Down-regulation
Other_IKK_IKBKB_ST	Q04206	RELA	O14920	IKBKB	S311	F309L	309	Missense	proximal	-2	no	29.249	29.283	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	16.613	Up-regulation
Other_IKK_IKBKB_ST	Q04206	RELA	O14920	IKBKB	S311	E307K	307	Missense	distal	-4	no	29.249	26.791	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	16.613	Down-regulation
Other_IKK_IKBKB_ST	Q04206	RELA	O14920	IKBKB	S311	T308A	308	Missense	distal	-3	no	29.249	29.301	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	16.613	Up-regulation
Other_IKK_IKBKB_ST	Q04206	RELA	O14920	IKBKB	S468	V469I	469	Missense	proximal	1	no	24.405	26.657	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	16.613	Up-regulation
Other_IKK_IKBKB_ST	Q04206	RELA	O14920	IKBKB	S472	V469I	469	Missense	distal	-3	no	20.019	19.411	EPSD	TCGA;ICGC;COSMIC	16.613	Down-regulation
Other_IKK_IKBKB_ST	Q04206	RELA	O14920	IKBKB	S536	S529L	529	Missense	distal	-7	no	35.152	33.854	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC;GDSC;CCLE	16.613	Down-regulation
Other_IKK_IKBKB_ST	O15350	TP73	O14920	IKBKB	S471	A472T	472	Missense	proximal	1	no	22.729	22.455	PhosphoSitePlus	TCGA;COSMIC;GDSC;CCLE	16.613	Down-regulation
Other_IKK_IKBKB_ST	Q9H3D4	TP63	O14920	IKBKB	S30	E33K	33	Missense	distal	3	no	26.086	25.058	EPSD	TCGA;ICGC;COSMIC	16.613	Down-regulation
Other_IKK_IKBKB_ST	Q9H3D4	TP63	O14920	IKBKB	S30	R37Q	37	Missense	distal	7	no	26.086	26.254	EPSD	TCGA;ICGC;COSMIC	16.613	Up-regulation
Other_IKK_IKBKB_ST	Q9H3D4	TP63	O14920	IKBKB	S30	V23I	23	Missense	distal	-7	no	26.086	26.177	EPSD	TCGA;ICGC;COSMIC	16.613	Up-regulation
Other_IKK_IKBKB_ST	Q9H3D4	TP63	O14920	IKBKB	S43	R37Q	37	Missense	distal	-6	no	18.071	17.712	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	16.613	Down-regulation
Other_IKK_IKBKB_ST	Q9H3D4	TP63	O14920	IKBKB	S43	S38F	38	Missense	distal	-5	no	18.071	17.834	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	16.613	Down-regulation
Other_IKK_IKBKB_ST	Q9H3D4	TP63	O14920	IKBKB	S51	I58T	58	Missense	distal	7	no	17.904	18.240	PhosphoSitePlus;EPSD	TCGA;ICGC;COSMIC	16.613	Up-regulation
Other_IKK_IKBKB_ST	Q9H3D4	TP63	O14920	IKBKB	S51	E53Q	53	Missense	proximal	2	no	17.904	17.362	PhosphoSitePlus;EPSD	TCGA;ICGC;COSMIC	16.613	Down-regulation
Other_IKK_IKBKB_ST	Q9H3D4	TP63	O14920	IKBKB	S395	P396T	396	Missense	proximal	1	no	23.136	21.373	EPSD	TCGA;COSMIC	16.613	Down-regulation
Other_IKK_IKBKB_ST	Q9H3D4	TP63	O14920	IKBKB	S395	T388I	388	Missense	distal	-7	no	23.136	20.527	EPSD	TCGA;ICGC;COSMIC	16.613	Down-regulation
Other_IKK_IKBKB_ST	Q9H3D4	TP63	O14920	IKBKB	S395	D398N	398	Missense	distal	3	no	23.136	23.233	EPSD	TCGA;ICGC;COSMIC	16.613	Up-regulation
Other_IKK_IKBKB_ST	Q9H3D4	TP63	O14920	IKBKB	S395	S389F	389	Missense	distal	-6	no	23.136	21.987	EPSD	TCGA;ICGC;COSMIC	16.613	Down-regulation
Other_IKK_IKBKB_ST	Q9H3D4	TP63	O14920	IKBKB	S395	D397G	397	Missense	proximal	2	no	23.136	22.603	EPSD	TCGA;COSMIC	16.613	Down-regulation
Other_IKK_IKBKB_ST	Q9H3D4	TP63	O14920	IKBKB	S395	R393Q	393	Missense	proximal	-2	no	23.136	23.543	EPSD	TCGA;COSMIC	16.613	Up-regulation
Other_IKK_IKBKB_ST	Q9H3D4	TP63	O14920	IKBKB	S395	K391N	391	Missense	distal	-4	no	23.136	20.589	EPSD	TCGA;COSMIC	16.613	Down-regulation
Other_IKK_IKBKB_ST	Q9H3D4	TP63	O14920	IKBKB	S612	E609K	609	Missense	distal	-3	no	17.344	17.736	EPSD	TCGA;COSMIC	16.613	Up-regulation
Other_IKK_IKBKB_ST	Q9H3D4	TP63	O14920	IKBKB	S612	H615Y	615	Missense	distal	3	no	17.344	16.532	EPSD	TCGA;COSMIC	16.613	Loss
Other_IKK_IKBKB_ST	Q9H3D4	TP63	O14920	IKBKB	S612	F610L	610	Missense	proximal	-2	no	17.344	17.378	EPSD	TCGA;COSMIC	16.613	Up-regulation
Other_IKK_IKBKB_ST	P19838	NFKB1	O14920	IKBKB	S80	S74C	74	Missense	distal	-6	no	17.328	16.141	EPSD	TCGA	16.613	Loss
Other_IKK_IKBKB_ST	P19838	NFKB1	O14920	IKBKB	S80	K79N	79	Missense	proximal	-1	no	17.328	17.275	EPSD	TCGA;COSMIC	16.613	Down-regulation
Other_IKK_IKBKB_ST	P25963	NFKBIA	O14920	IKBKB	S32	D31N	31	Missense	proximal	-1	no	36.028	35.582	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	16.613	Down-regulation
Other_IKK_IKBKB_ST	P25963	NFKBIA	O14920	IKBKB	S32	D27H	27	Missense	distal	-5	no	36.028	36.128	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	16.613	Up-regulation
Other_IKK_IKBKB_ST	P25963	NFKBIA	O14920	IKBKB	S36	E41K	41	Missense	distal	5	no	37.410	38.273	PhosphoSitePlus;EPSD	TCGA;ICGC	16.613	Up-regulation
Other_IKK_IKBKB_ST	P25963	NFKBIA	O14920	IKBKB	S36	D31N	31	Missense	distal	-5	no	37.410	37.725	PhosphoSitePlus;EPSD	TCGA;ICGC;COSMIC	16.613	Up-regulation
Other_IKK_IKBKB_ST	P25963	NFKBIA	O14920	IKBKB	S36	Y42C	42	Missense	distal	6	no	37.410	37.168	PhosphoSitePlus;EPSD	TCGA;ICGC;COSMIC	16.613	Down-regulation
Other_IKK_IKBKB_ST	P25963	NFKBIA	O14920	IKBKB	S283	E282K	282	Missense	proximal	-1	no	17.052	16.992	EPSD	TCGA;COSMIC	16.613	Down-regulation
Other_IKK_IKBKB_ST	P25963	NFKBIA	O14920	IKBKB	S283	D290G	290	Missense	distal	7	no	17.052	16.926	EPSD	TCGA	16.613	Down-regulation
Other_IKK_IKBKB_ST	P25963	NFKBIA	O14920	IKBKB	S288	E282K	282	Missense	distal	-6	no	17.602	17.425	EPSD	TCGA;COSMIC	16.613	Down-regulation
Other_IKK_IKBKB_ST	P25963	NFKBIA	O14920	IKBKB	S288	D290G	290	Missense	proximal	2	no	17.602	17.069	EPSD	TCGA	16.613	Down-regulation
Other_IKK_IKBKB_ST	P25963	NFKBIA	O14920	IKBKB	S288	S293T	293	Missense	distal	5	no	17.602	16.880	EPSD	TCGA;COSMIC	16.613	Down-regulation
Other_IKK_IKBKB_ST	P01100	FOS	O14920	IKBKB	S258	M262I	262	Missense	distal	4	no	25.711	18.215	EPSD	TCGA;COSMIC	16.613	Down-regulation
Other_IKK_IKBKB_ST	P01100	FOS	O14920	IKBKB	S258	S252L	252	Missense	distal	-6	no	25.711	25.076	EPSD	TCGA;ICGC;COSMIC	16.613	Down-regulation
Other_IKK_IKBKB_ST	P01100	FOS	O14920	IKBKB	S261	M262I	262	Missense	proximal	1	no	23.494	25.833	EPSD	TCGA;COSMIC	16.613	Up-regulation
Other_IKK_IKBKB_ST	P01100	FOS	O14920	IKBKB	S281	P275Q	275	Missense	distal	-6	no	18.030	17.272	EPSD	TCGA;COSMIC	16.613	Down-regulation
Other_IKK_IKBKB_ST	P01100	FOS	O14920	IKBKB	S281	A276T	276	Missense	distal	-5	no	18.030	18.096	EPSD	TCGA;ICGC;COSMIC	16.613	Up-regulation
Other_IKK_IKBKB_ST	P01100	FOS	O14920	IKBKB	S308	M313I	313	Missense	distal	5	no	27.703	22.371	PhosphoSitePlus	TCGA;ICGC;COSMIC	16.613	Down-regulation
Other_IKK_IKBKB_ST	P01100	FOS	O14920	IKBKB	S362	S369P	369	Missense	distal	7	no	19.817	19.101	EPSD	TCGA	16.613	Down-regulation
Other_IKK_IKBKB_ST	P01100	FOS	O14920	IKBKB	S362	N365I	365	Missense	distal	3	no	19.817	15.693	EPSD	TCGA;ICGC;COSMIC	16.613	Loss
Other_IKK_IKBKB_ST	P01100	FOS	O14920	IKBKB	S362	S363N	363	Missense	proximal	1	no	19.817	20.532	EPSD	TCGA;COSMIC	16.613	Up-regulation
Other_IKK_IKBKB_ST	P01100	FOS	O14920	IKBKB	S364	S369P	369	Missense	distal	5	no	24.792	24.591	EPSD	TCGA	16.613	Down-regulation
Other_IKK_IKBKB_ST	P01100	FOS	O14920	IKBKB	S364	N365I	365	Missense	proximal	1	no	24.792	26.241	EPSD	TCGA;ICGC;COSMIC	16.613	Up-regulation
Other_IKK_IKBKB_ST	P01100	FOS	O14920	IKBKB	S364	S363N	363	Missense	proximal	-1	no	24.792	24.647	EPSD	TCGA;COSMIC	16.613	Down-regulation
Other_IKK_IKBKB_ST	P01100	FOS	O14920	IKBKB	S368	S369P	369	Missense	proximal	1	no	20.545	21.606	EPSD	TCGA	16.613	Up-regulation
Other_IKK_IKBKB_ST	P01100	FOS	O14920	IKBKB	S368	N365I	365	Missense	distal	-3	no	20.545	19.233	EPSD	TCGA;ICGC;COSMIC	16.613	Down-regulation
Other_IKK_IKBKB_ST	P01100	FOS	O14920	IKBKB	S368	S363N	363	Missense	distal	-5	no	20.545	20.816	EPSD	TCGA;COSMIC	16.613	Up-regulation
Other_IKK_IKBKB_ST	P01100	FOS	O14920	IKBKB	S371	S369P	369	Missense	proximal	-2	no	17.581	18.467	EPSD	TCGA	16.613	Up-regulation
Other_IKK_IKBKB_ST	P01100	FOS	O14920	IKBKB	S371	N365I	365	Missense	distal	-6	no	17.581	16.246	EPSD	TCGA;ICGC;COSMIC	16.613	Loss
Other_IKK_IKBKB_ST	P01100	FOS	O14920	IKBKB	S374	S369P	369	Missense	distal	-5	no	18.156	18.188	EPSD	TCGA	16.613	Up-regulation
Other_IKK_IKBKB_ST	Q01201	RELB	O14920	IKBKB	S151	G154A	154	Missense	distal	3	no	19.299	19.091	EPSD	TCGA;COSMIC	16.613	Down-regulation
Other_IKK_IKBKB_ST	Q01201	RELB	O14920	IKBKB	S151	S148L	148	Missense	distal	-3	no	19.299	18.891	EPSD	TCGA;COSMIC	16.613	Down-regulation
Other_IKK_IKBKB_ST	Q01201	RELB	O14920	IKBKB	S151	L153F	153	Missense	proximal	2	no	19.299	19.201	EPSD	TCGA;COSMIC	16.613	Down-regulation
Other_IKK_IKBKB_ST	Q01201	RELB	O14920	IKBKB	S151	R147C	147	Missense	distal	-4	no	19.299	15.911	EPSD	TCGA;COSMIC	16.613	Loss
Other_IKK_IKBKB_ST	Q92574	TSC1	O14920	IKBKB	S108	S102F	102	Missense	distal	-6	no	21.638	20.489	EPSD	TCGA;ICGC	16.613	Down-regulation
Other_IKK_IKBKB_ST	Q92574	TSC1	O14920	IKBKB	S205	R204C	204	Missense	proximal	-1	no	23.388	23.522	EPSD	TCGA;COSMIC	16.613	Up-regulation
Other_IKK_IKBKB_ST	Q92574	TSC1	O14920	IKBKB	S295	D299N	299	Missense	distal	4	no	21.638	21.623	EPSD	TCGA;ICGC;COSMIC	16.613	Down-regulation
Other_IKK_IKBKB_ST	Q92574	TSC1	O14920	IKBKB	S295	T293A	293	Missense	proximal	-2	no	21.638	21.422	EPSD	TCGA;ICGC;COSMIC	16.613	Down-regulation
Other_IKK_IKBKB_ST	Q92574	TSC1	O14920	IKBKB	S295	R288H	288	Missense	distal	-7	no	21.638	20.444	EPSD	TCGA;ICGC;COSMIC	16.613	Down-regulation
Other_IKK_IKBKB_ST	Q92574	TSC1	O14920	IKBKB	S427	L432V	432	Missense	distal	5	no	17.786	16.304	EPSD	TCGA	16.613	Loss
Other_IKK_IKBKB_ST	Q92574	TSC1	O14920	IKBKB	S472	K477N	477	Missense	distal	5	no	24.119	20.133	EPSD	TCGA;ICGC;COSMIC	16.613	Down-regulation
Other_IKK_IKBKB_ST	Q92574	TSC1	O14920	IKBKB	S483	K477N	477	Missense	distal	-6	no	22.413	22.397	EPSD	TCGA;ICGC;COSMIC	16.613	Down-regulation
Other_IKK_IKBKB_ST	Q92574	TSC1	O14920	IKBKB	S511	D504N	504	Missense	distal	-7	no	26.545	27.385	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	16.613	Up-regulation
Other_IKK_IKBKB_ST	Q92574	TSC1	O14920	IKBKB	S511	F507L	507	Missense	distal	-4	no	26.545	26.148	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	16.613	Down-regulation
Other_IKK_IKBKB_ST	Q92574	TSC1	O14920	IKBKB	S511	R509L	509	Missense	proximal	-2	no	26.545	27.542	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	16.613	Up-regulation
Other_IKK_IKBKB_ST	Q92574	TSC1	O14920	IKBKB	S521	G528D	528	Missense	distal	7	no	17.930	18.056	EPSD	TCGA;ICGC;COSMIC	16.613	Up-regulation
Other_IKK_IKBKB_ST	Q92574	TSC1	O14920	IKBKB	S525	A529S	529	Missense	distal	4	no	14.236	16.788	EPSD	TCGA;ICGC;COSMIC	16.613	Gain
Other_IKK_IKBKB_ST	Q92574	TSC1	O14920	IKBKB	S526	G528D	528	Missense	proximal	2	no	19.060	19.593	EPSD	TCGA;ICGC;COSMIC	16.613	Up-regulation
Other_IKK_IKBKB_ST	Q92574	TSC1	O14920	IKBKB	S526	V531M	531	Missense	distal	5	no	19.060	23.445	EPSD	TCGA;ICGC;COSMIC	16.613	Up-regulation
Other_IKK_IKBKB_ST	Q92574	TSC1	O14920	IKBKB	S526	A529S	529	Missense	distal	3	no	19.060	20.503	EPSD	TCGA;ICGC;COSMIC	16.613	Up-regulation
Other_IKK_IKBKB_ST	Q92574	TSC1	O14920	IKBKB	S526	P533H	533	Missense	distal	7	no	19.060	19.139	EPSD	TCGA;ICGC;COSMIC	16.613	Up-regulation
Other_IKK_IKBKB_ST	Q92574	TSC1	O14920	IKBKB	S530	G528D	528	Missense	proximal	-2	no	19.116	18.001	EPSD	TCGA;ICGC;COSMIC	16.613	Down-regulation
Other_IKK_IKBKB_ST	Q92574	TSC1	O14920	IKBKB	S530	V531M	531	Missense	proximal	1	no	19.116	19.029	EPSD	TCGA;ICGC;COSMIC	16.613	Down-regulation
Other_IKK_IKBKB_ST	Q92574	TSC1	O14920	IKBKB	S530	A529S	529	Missense	proximal	-1	no	19.116	19.274	EPSD	TCGA;ICGC;COSMIC	16.613	Up-regulation
Other_IKK_IKBKB_ST	Q92574	TSC1	O14920	IKBKB	S530	P535H	535	Missense	distal	5	no	19.116	17.969	EPSD	TCGA;ICGC;COSMIC	16.613	Down-regulation
Other_IKK_IKBKB_ST	Q92574	TSC1	O14920	IKBKB	S530	P533H	533	Missense	distal	3	no	19.116	19.231	EPSD	TCGA;ICGC;COSMIC	16.613	Up-regulation
Other_IKK_IKBKB_ST	Q92574	TSC1	O14920	IKBKB	S539	P535H	535	Missense	distal	-4	no	16.590	18.106	EPSD	TCGA;ICGC;COSMIC	16.613	Gain
Other_IKK_IKBKB_ST	Q92574	TSC1	O14920	IKBKB	S539	P533H	533	Missense	distal	-6	no	16.590	16.738	EPSD	TCGA;ICGC;COSMIC	16.613	Gain
Other_IKK_IKBKB_ST	Q92574	TSC1	O14920	IKBKB	S565	S565N	565	Missense	central	0	yes	17.020	0.000	EPSD	TCGA;ICGC;COSMIC	16.613	Loss
Other_IKK_IKBKB_ST	Q92574	TSC1	O14920	IKBKB	S575	S575F	575	Missense	central	0	yes	26.423	0.000	EPSD	TCGA;ICGC;COSMIC	16.613	Loss
Other_IKK_IKBKB_ST	Q92574	TSC1	O14920	IKBKB	S579	S575F	575	Missense	distal	-4	no	19.544	13.309	EPSD	TCGA;ICGC;COSMIC	16.613	Loss
Other_IKK_IKBKB_ST	Q92574	TSC1	O14920	IKBKB	S1038	S1032N	1032	Missense	distal	-6	no	20.599	20.723	EPSD	TCGA;ICGC	16.613	Up-regulation
Other_IKK_IKBKB_ST	Q92574	TSC1	O14920	IKBKB	S1039	S1032N	1032	Missense	distal	-7	no	22.000	23.192	EPSD	TCGA;ICGC	16.613	Up-regulation
Other_IKK_IKBKB_ST	Q92574	TSC1	O14920	IKBKB	S1073	T1076A	1076	Missense	distal	3	no	22.822	22.373	EPSD	TCGA;ICGC;COSMIC	16.613	Down-regulation
Other_IKK_IKBKB_ST	Q92574	TSC1	O14920	IKBKB	S1073	A1070V	1070	Missense	distal	-3	no	22.822	22.363	EPSD	TCGA;ICGC;COSMIC	16.613	Down-regulation
Other_IKK_IKBKB_ST	Q92574	TSC1	O14920	IKBKB	S1073	A1072V	1072	Missense	proximal	-1	no	22.822	23.240	EPSD	TCGA;ICGC;COSMIC	16.613	Up-regulation
Other_IKK_IKBKB_ST	Q92574	TSC1	O14920	IKBKB	S1080	T1076A	1076	Missense	distal	-4	no	21.410	20.968	EPSD	TCGA;ICGC;COSMIC	16.613	Down-regulation
Other_IKK_IKBKB_ST	Q92574	TSC1	O14920	IKBKB	S1111	D1105N	1105	Missense	distal	-6	no	16.869	17.216	EPSD	TCGA;ICGC;COSMIC	16.613	Up-regulation
Other_IKK_IKBKB_ST	Q92574	TSC1	O14920	IKBKB	S1111	G1108R	1108	Missense	distal	-3	no	16.869	17.296	EPSD	TCGA;ICGC;COSMIC	16.613	Up-regulation
Other_IKK_IKBKB_ST	Q92574	TSC1	O14920	IKBKB	S1112	G1108R	1108	Missense	distal	-4	no	12.763	16.728	EPSD	TCGA;ICGC;COSMIC	16.613	Gain
Other_IKK_IKBKB_ST	Q92574	TSC1	O14920	IKBKB	S1147	P1143L	1143	Missense	distal	-4	no	19.020	15.912	EPSD	TCGA;ICGC;COSMIC	16.613	Loss
Other_IKK_IKBKB_ST	Q92574	TSC1	O14920	IKBKB	S1147	P1140L	1140	Missense	distal	-7	no	19.020	18.996	EPSD	TCGA;ICGC;COSMIC	16.613	Down-regulation
Other_IKK_IKBKB_ST	O95999	BCL10	O14920	IKBKB	S134	D139N	139	Missense	distal	5	no	20.709	21.242	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	16.613	Up-regulation
Other_IKK_IKBKB_ST	O95999	BCL10	O14920	IKBKB	S136	F143L	143	Missense	distal	7	no	32.835	33.338	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	16.613	Up-regulation
Other_IKK_IKBKB_ST	O95999	BCL10	O14920	IKBKB	S136	D139N	139	Missense	distal	3	no	32.835	32.933	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	16.613	Up-regulation
Other_IKK_IKBKB_ST	O95999	BCL10	O14920	IKBKB	S138	F143L	143	Missense	distal	5	no	28.430	30.452	PhosphoSitePlus;EPSD	TCGA;ICGC;COSMIC	16.613	Up-regulation
Other_IKK_IKBKB_ST	O95999	BCL10	O14920	IKBKB	S138	D139N	139	Missense	proximal	1	no	28.430	28.889	PhosphoSitePlus;EPSD	TCGA;ICGC;COSMIC	16.613	Up-regulation
Other_IKK_IKBKB_ST	O95999	BCL10	O14920	IKBKB	S141	F143L	143	Missense	proximal	2	no	25.356	25.454	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	16.613	Up-regulation
Other_IKK_IKBKB_ST	O95999	BCL10	O14920	IKBKB	S141	D139N	139	Missense	proximal	-2	no	25.356	25.676	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	16.613	Up-regulation
Other_IKK_IKBKB_ST	O95999	BCL10	O14920	IKBKB	S144	D139N	139	Missense	distal	-5	no	16.566	16.881	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	16.613	Gain
Other_IKK_IKBKB_ST	O95999	BCL10	O14920	IKBKB	S167	S167F	167	Missense	central	0	yes	16.643	0.000	EPSD	TCGA;ICGC;COSMIC	16.613	Loss
Other_IKK_IKBKB_ST	O95999	BCL10	O14920	IKBKB	S167	S170F	170	Missense	distal	3	no	16.643	12.670	EPSD	TCGA;ICGC;COSMIC	16.613	Loss
Other_IKK_IKBKB_ST	O95999	BCL10	O14920	IKBKB	S170	S167F	167	Missense	distal	-3	no	16.668	15.924	EPSD	TCGA;ICGC;COSMIC	16.613	Loss
Other_IKK_IKBKB_ST	O95999	BCL10	O14920	IKBKB	S170	S170F	170	Missense	central	0	yes	16.668	0.000	EPSD	TCGA;ICGC;COSMIC	16.613	Loss
Other_IKK_IKBKB_ST	P42858	HTT	O14920	IKBKB	S459	E456K	456	Missense	distal	-3	no	21.565	21.956	EPSD	TCGA;ICGC;COSMIC	16.613	Up-regulation
Other_IKK_IKBKB_ST	P42858	HTT	O14920	IKBKB	S459	S462N	462	Missense	distal	3	no	21.565	20.790	EPSD	TCGA;ICGC;COSMIC	16.613	Down-regulation
Other_IKK_IKBKB_ST	P42858	HTT	O14920	IKBKB	S1111	E1114K	1114	Missense	distal	3	no	20.466	19.438	EPSD	TCGA;ICGC;COSMIC	16.613	Down-regulation
Other_IKK_IKBKB_ST	P42858	HTT	O14920	IKBKB	S1111	S1108L	1108	Missense	distal	-3	no	20.466	20.058	EPSD	TCGA;ICGC;COSMIC	16.613	Down-regulation
Other_IKK_IKBKB_ST	P42858	HTT	O14920	IKBKB	S1111	S1104Y	1104	Missense	distal	-7	no	20.466	17.993	EPSD	TCGA;ICGC;COSMIC;GDSC;CCLE	16.613	Down-regulation
Other_IKK_IKBKB_ST	P42858	HTT	O14920	IKBKB	S1171	P1170R	1170	Missense	proximal	-1	no	16.552	16.715	EPSD	TCGA;ICGC;COSMIC	16.613	Gain
Other_IKK_IKBKB_ST	P42858	HTT	O14920	IKBKB	S1199	Q1193K	1193	Missense	distal	-6	no	18.582	19.739	EPSD	TCGA;ICGC;COSMIC	16.613	Up-regulation
Other_IKK_IKBKB_ST	P42858	HTT	O14920	IKBKB	S1199	L1198S	1198	Missense	proximal	-1	no	18.582	18.735	EPSD	TCGA;ICGC;COSMIC	16.613	Up-regulation
Other_IKK_IKBKB_ST	P42858	HTT	O14920	IKBKB	S1199	P1200L	1200	Missense	proximal	1	no	18.582	18.290	EPSD	TCGA;ICGC;COSMIC	16.613	Down-regulation
Other_IKK_IKBKB_ST	P42858	HTT	O14920	IKBKB	S1229	S1224F	1224	Missense	distal	-5	no	16.875	16.637	EPSD	TCGA;ICGC;COSMIC	16.613	Down-regulation
Other_IKK_IKBKB_ST	P42858	HTT	O14920	IKBKB	S1229	S1224T	1224	Missense	distal	-5	no	16.875	16.911	EPSD	TCGA;ICGC;COSMIC	16.613	Up-regulation
Other_IKK_IKBKB_ST	P42858	HTT	O14920	IKBKB	S2328	E2324K	2324	Missense	distal	-4	no	18.309	15.851	EPSD	TCGA;ICGC;COSMIC	16.613	Loss
Other_IKK_IKBKB_ST	P42858	HTT	O14920	IKBKB	S2582	A2586S	2586	Missense	distal	4	no	14.154	16.705	EPSD	TCGA;ICGC;COSMIC	16.613	Gain
Other_IKK_IKBKB_ST	P42858	HTT	O14920	IKBKB	S2651	P2647S	2647	Missense	distal	-4	no	16.872	20.396	EPSD	TCGA;ICGC;COSMIC	16.613	Up-regulation
Other_IKK_IKBKB_ST	P42858	HTT	O14920	IKBKB	S2651	T2654M	2654	Missense	distal	3	no	16.872	17.159	EPSD	TCGA;ICGC;COSMIC	16.613	Up-regulation
Other_IKK_IKBKB_ST	P42858	HTT	O14920	IKBKB	S2655	T2654M	2654	Missense	proximal	-1	no	21.289	21.164	EPSD	TCGA;ICGC;COSMIC	16.613	Down-regulation
Other_IKK_IKBKB_ST	P42858	HTT	O14920	IKBKB	S3030	S3025N	3025	Missense	distal	-5	no	16.413	16.684	EPSD	TCGA;ICGC;COSMIC	16.613	Gain
Other_IKK_IKBKB_ST	P19438	TNFRSF1A	O14920	IKBKB	S381	G379E	379	Missense	proximal	-2	no	17.341	16.273	PhosphoSitePlus	TCGA	16.613	Loss
Other_IKK_IKBKB_ST	P19438	TNFRSF1A	O14920	IKBKB	S381	R377C	377	Missense	distal	-4	no	17.341	13.953	PhosphoSitePlus	TCGA	16.613	Loss
Other_IKK_IKBKB_ST	P19438	TNFRSF1A	O14920	IKBKB	S381	E384K	384	Missense	distal	3	no	17.341	16.313	PhosphoSitePlus	TCGA;COSMIC	16.613	Loss
Other_IKK_IKBKB_ST	P19438	TNFRSF1A	O14920	IKBKB	S402	A405V	405	Missense	distal	3	no	17.485	13.604	EPSD	TCGA;COSMIC	16.613	Loss
Other_IKK_IKBKB_ST	Q6P2E9	EDC4	O14920	IKBKB	S55	P52S	52	Missense	distal	-3	no	25.388	25.935	EPSD	TCGA;ICGC;COSMIC	16.613	Up-regulation
Other_IKK_IKBKB_ST	Q6P2E9	EDC4	O14920	IKBKB	S103	S106C	106	Missense	distal	3	no	16.885	13.904	EPSD	TCGA;ICGC;COSMIC	16.613	Loss
Other_IKK_IKBKB_ST	Q6P2E9	EDC4	O14920	IKBKB	S106	S106C	106	Missense	central	0	yes	18.656	0.000	EPSD	TCGA;ICGC;COSMIC	16.613	Loss
Other_IKK_IKBKB_ST	Q6P2E9	EDC4	O14920	IKBKB	S107	S106C	106	Missense	proximal	-1	no	18.539	18.839	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	16.613	Up-regulation
Other_IKK_IKBKB_ST	Q6P2E9	EDC4	O14920	IKBKB	S621	S626I	626	Missense	distal	5	no	23.268	20.915	EPSD	TCGA;ICGC;COSMIC	16.613	Down-regulation
Other_IKK_IKBKB_ST	Q6P2E9	EDC4	O14920	IKBKB	S622	S626I	626	Missense	distal	4	no	20.619	15.454	EPSD	TCGA;ICGC;COSMIC	16.613	Loss
Other_IKK_IKBKB_ST	Q6P2E9	EDC4	O14920	IKBKB	S623	S626I	626	Missense	distal	3	no	24.194	19.296	EPSD	TCGA;ICGC;COSMIC	16.613	Down-regulation
Other_IKK_IKBKB_ST	Q6P2E9	EDC4	O14920	IKBKB	S624	S626I	626	Missense	proximal	2	no	19.488	19.204	EPSD	TCGA;ICGC;COSMIC	16.613	Down-regulation
Other_IKK_IKBKB_ST	Q6P2E9	EDC4	O14920	IKBKB	S645	S638N	638	Missense	distal	-7	no	17.142	18.334	EPSD	TCGA;ICGC;COSMIC	16.613	Up-regulation
Other_IKK_IKBKB_ST	Q6P2E9	EDC4	O14920	IKBKB	S645	T647I	647	Missense	proximal	2	no	17.142	16.737	EPSD	TCGA;ICGC;COSMIC	16.613	Down-regulation
Other_IKK_IKBKB_ST	Q6P2E9	EDC4	O14920	IKBKB	S664	P657L	657	Missense	distal	-7	no	17.590	17.566	EPSD	TCGA;ICGC;COSMIC	16.613	Down-regulation
Other_IKK_IKBKB_ST	Q6P2E9	EDC4	O14920	IKBKB	S664	S668G	668	Missense	distal	4	no	17.590	12.689	EPSD	TCGA;ICGC;COSMIC	16.613	Loss
Other_IKK_IKBKB_ST	Q6P2E9	EDC4	O14920	IKBKB	S670	S668G	668	Missense	proximal	-2	no	23.996	24.709	EPSD	TCGA;ICGC;COSMIC	16.613	Up-regulation
Other_IKK_IKBKB_ST	Q6P2E9	EDC4	O14920	IKBKB	S672	R678S	678	Missense	distal	6	no	18.921	18.297	EPSD	TCGA;ICGC;COSMIC	16.613	Down-regulation
Other_IKK_IKBKB_ST	Q6P2E9	EDC4	O14920	IKBKB	S672	S668G	668	Missense	distal	-4	no	18.921	12.646	EPSD	TCGA;ICGC;COSMIC	16.613	Loss
Other_IKK_IKBKB_ST	Q6P2E9	EDC4	O14920	IKBKB	S676	R678S	678	Missense	proximal	2	no	19.512	19.617	EPSD	TCGA;ICGC;COSMIC	16.613	Up-regulation
Other_IKK_IKBKB_ST	Q6P2E9	EDC4	O14920	IKBKB	S676	P682S	682	Missense	distal	6	no	19.512	18.188	EPSD	TCGA;ICGC;COSMIC	16.613	Down-regulation
Other_IKK_IKBKB_ST	Q6P2E9	EDC4	O14920	IKBKB	S734	A739T	739	Missense	distal	5	no	18.167	17.129	EPSD	TCGA;ICGC	16.613	Down-regulation
Other_IKK_IKBKB_ST	Q6P2E9	EDC4	O14920	IKBKB	S734	L740M	740	Missense	distal	6	no	18.167	17.393	EPSD	TCGA;ICGC;COSMIC	16.613	Down-regulation
Other_IKK_IKBKB_ST	Q6P2E9	EDC4	O14920	IKBKB	S735	A739T	739	Missense	distal	4	no	18.217	17.265	EPSD	TCGA;ICGC	16.613	Down-regulation
Other_IKK_IKBKB_ST	Q6P2E9	EDC4	O14920	IKBKB	S735	L740M	740	Missense	distal	5	no	18.217	21.120	EPSD	TCGA;ICGC;COSMIC	16.613	Up-regulation
Other_IKK_IKBKB_ST	Q6P2E9	EDC4	O14920	IKBKB	S771	A770V	770	Missense	proximal	-1	no	18.572	18.990	EPSD	TCGA;ICGC	16.613	Up-regulation
Other_IKK_IKBKB_ST	Q6P2E9	EDC4	O14920	IKBKB	S809	E812K	812	Missense	distal	3	no	17.684	16.656	EPSD	TCGA;ICGC;COSMIC	16.613	Down-regulation
Other_IKK_IKBKB_ST	Q6P2E9	EDC4	O14920	IKBKB	S839	S839N	839	Missense	central	0	yes	20.243	0.000	EPSD	TCGA;ICGC	16.613	Loss
Other_IKK_IKBKB_ST	Q6P2E9	EDC4	O14920	IKBKB	S839	R846M	846	Missense	distal	7	no	20.243	21.097	EPSD	TCGA;ICGC;COSMIC	16.613	Up-regulation
Other_IKK_IKBKB_ST	Q6P2E9	EDC4	O14920	IKBKB	S879	E877Q	877	Missense	proximal	-2	no	17.167	17.704	EPSD	TCGA;ICGC;COSMIC	16.613	Up-regulation
Other_IKK_IKBKB_ST	Q6P2E9	EDC4	O14920	IKBKB	S887	A889V	889	Missense	proximal	2	no	19.001	18.997	EPSD	TCGA;ICGC;COSMIC	16.613	Down-regulation
Other_IKK_IKBKB_ST	Q6P2E9	EDC4	O14920	IKBKB	S936	M934I	934	Missense	proximal	-2	no	19.893	20.350	EPSD	TCGA;ICGC;COSMIC;GDSC;CCLE	16.613	Up-regulation
Other_IKK_IKBKB_ST	Q6P2E9	EDC4	O14920	IKBKB	S936	R937L	937	Missense	proximal	1	no	19.893	20.271	EPSD	TCGA;ICGC	16.613	Up-regulation
Other_IKK_IKBKB_ST	Q6P2E9	EDC4	O14920	IKBKB	S936	Q942H	942	Missense	distal	6	no	19.893	19.551	EPSD	TCGA;ICGC;COSMIC	16.613	Down-regulation
Other_IKK_IKBKB_ST	Q6P2E9	EDC4	O14920	IKBKB	S1058	P1053S	1053	Missense	distal	-5	no	19.010	18.977	EPSD	TCGA;ICGC;COSMIC	16.613	Down-regulation
Other_IKK_IKBKB_ST	Q6P2E9	EDC4	O14920	IKBKB	S1058	P1061H	1061	Missense	distal	3	no	19.010	19.125	EPSD	TCGA;ICGC	16.613	Up-regulation
Other_IKK_IKBKB_ST	Q6P2E9	EDC4	O14920	IKBKB	S1158	R1162Q	1162	Missense	distal	4	no	26.098	28.092	EPSD	TCGA;ICGC;COSMIC	16.613	Up-regulation
Other_IKK_IKBKB_ST	Q6P2E9	EDC4	O14920	IKBKB	S1380	R1386W	1386	Missense	distal	6	no	18.886	20.179	EPSD	TCGA;ICGC;COSMIC	16.613	Up-regulation
Other_IKK_IKBKB_ST	Q6P2E9	EDC4	O14920	IKBKB	S1380	N1379S	1379	Missense	proximal	-1	no	18.886	19.030	EPSD	TCGA;ICGC;COSMIC	16.613	Up-regulation
Other_IKK_IKBKB_ST	P42771	CDKN2A	O14920	IKBKB	S8	S12L	12	Missense	distal	4	no	17.179	15.334	PhosphoSitePlus	TCGA;ICGC;COSMIC	16.613	Loss
Other_IKK_IKBKB_ST	P42771	CDKN2A	O14920	IKBKB	S8	S8I	8	Missense	central	0	yes	17.179	0.000	PhosphoSitePlus	TCGA;ICGC;COSMIC	16.613	Loss
Other_IKK_IKBKB_ST	P42771	CDKN2A	O14920	IKBKB	S8	S8R	8	Missense	central	0	yes	17.179	0.000	PhosphoSitePlus	TCGA;ICGC;COSMIC	16.613	Loss
Other_IKK_IKBKB_ST	P42771	CDKN2A	O14920	IKBKB	S8	D14G	14	Missense	distal	6	no	17.179	18.094	PhosphoSitePlus	TCGA;ICGC;COSMIC	16.613	Up-regulation
Other_IKK_IKBKB_ST	P42771	CDKN2A	O14920	IKBKB	S8	A13T	13	Missense	distal	5	no	17.179	16.141	PhosphoSitePlus	TCGA;ICGC;COSMIC	16.613	Loss
Other_IKK_IKBKB_ST	P21580	TNFAIP3	O14920	IKBKB	S79	N84K	84	Missense	distal	5	no	14.929	18.915	EPSD	TCGA	16.613	Gain
Other_IKK_IKBKB_ST	P21580	TNFAIP3	O14920	IKBKB	S471	P467H	467	Missense	distal	-4	no	15.298	16.814	EPSD	TCGA;ICGC;COSMIC	16.613	Gain
Other_IKK_IKBKB_ST	P21580	TNFAIP3	O14920	IKBKB	S550	P556H	556	Missense	distal	6	no	22.636	21.946	EPSD	TCGA;ICGC	16.613	Down-regulation
Other_IKK_IKBKB_ST	P21580	TNFAIP3	O14920	IKBKB	S550	T543A	543	Missense	distal	-7	no	22.636	23.068	EPSD	TCGA;ICGC;COSMIC	16.613	Up-regulation
Other_IKK_IKBKB_ST	P21580	TNFAIP3	O14920	IKBKB	S573	R569Q	569	Missense	distal	-4	no	20.858	19.605	EPSD	TCGA;ICGC;GDSC;CCLE	16.613	Down-regulation
Other_IKK_IKBKB_ST	P21580	TNFAIP3	O14920	IKBKB	S645	A648V	648	Missense	distal	3	no	18.626	14.744	EPSD	TCGA;ICGC;COSMIC	16.613	Loss
Other_IKK_IKBKB_ST	P21580	TNFAIP3	O14920	IKBKB	S698	S698L	698	Missense	central	0	yes	18.728	0.000	EPSD	TCGA;ICGC;COSMIC	16.613	Loss
Other_IKK_IKBKB_ST	P21580	TNFAIP3	O14920	IKBKB	S698	R691M	691	Missense	distal	-7	no	18.728	19.324	EPSD	TCGA;ICGC;COSMIC	16.613	Up-regulation
Other_IKK_IKBKB_ST	Q9Y4G8	RAPGEF2	O14920	IKBKB	S501	S501P	501	Missense	central	0	yes	16.948	0.000	EPSD	TCGA;ICGC;COSMIC	16.613	Loss
Other_IKK_IKBKB_ST	Q9Y4G8	RAPGEF2	O14920	IKBKB	S501	P503L	503	Missense	proximal	2	no	16.948	17.084	EPSD	TCGA;ICGC;COSMIC	16.613	Up-regulation
Other_IKK_IKBKB_ST	Q9Y4G8	RAPGEF2	O14920	IKBKB	S501	R499H	499	Missense	proximal	-2	no	16.948	17.466	EPSD	TCGA;ICGC;COSMIC	16.613	Up-regulation
Other_IKK_IKBKB_ST	Q9Y4G8	RAPGEF2	O14920	IKBKB	S501	P503T	503	Missense	proximal	2	no	16.948	17.326	EPSD	TCGA;ICGC;COSMIC	16.613	Up-regulation
Other_IKK_IKBKB_ST	Q9Y4G8	RAPGEF2	O14920	IKBKB	S592	R595H	595	Missense	distal	3	no	18.810	18.932	EPSD	TCGA;ICGC;COSMIC	16.613	Up-regulation
Other_IKK_IKBKB_ST	Q9Y4G8	RAPGEF2	O14920	IKBKB	S592	S592L	592	Missense	central	0	yes	18.810	0.000	EPSD	TCGA;ICGC;COSMIC	16.613	Loss
Other_IKK_IKBKB_ST	Q9Y4G8	RAPGEF2	O14920	IKBKB	S592	S585G	585	Missense	distal	-7	no	18.810	19.032	EPSD	TCGA;ICGC;COSMIC	16.613	Up-regulation
Other_IKK_IKBKB_ST	Q9Y4G8	RAPGEF2	O14920	IKBKB	S698	D699E	699	Missense	proximal	1	no	16.765	17.331	EPSD	TCGA	16.613	Up-regulation
Other_IKK_IKBKB_ST	Q9Y4G8	RAPGEF2	O14920	IKBKB	S698	Q703H	703	Missense	distal	5	no	16.765	14.795	EPSD	TCGA;ICGC;COSMIC	16.613	Loss
Other_IKK_IKBKB_ST	Q9Y4G8	RAPGEF2	O14920	IKBKB	S698	E704K	704	Missense	distal	6	no	16.765	15.049	EPSD	TCGA;ICGC	16.613	Loss
Other_IKK_IKBKB_ST	Q9Y4G8	RAPGEF2	O14920	IKBKB	S912	R905C	905	Missense	distal	-7	no	17.157	15.340	EPSD	TCGA;ICGC;COSMIC;CCLE	16.613	Loss
Other_IKK_IKBKB_ST	Q9Y4G8	RAPGEF2	O14920	IKBKB	S912	R909Q	909	Missense	distal	-3	no	17.157	16.914	EPSD	TCGA;ICGC;COSMIC	16.613	Down-regulation
Other_IKK_IKBKB_ST	Q9Y4G8	RAPGEF2	O14920	IKBKB	S912	A911S	911	Missense	proximal	-1	no	17.157	17.314	EPSD	TCGA;ICGC;COSMIC	16.613	Up-regulation
Other_IKK_IKBKB_ST	Q9Y4G8	RAPGEF2	O14920	IKBKB	S1019	E1020K	1020	Missense	proximal	1	no	19.427	17.153	EPSD	TCGA;ICGC;COSMIC	16.613	Down-regulation
Other_IKK_IKBKB_ST	Q9Y4G8	RAPGEF2	O14920	IKBKB	S1019	V1024L	1024	Missense	distal	5	no	19.427	20.909	EPSD	TCGA;ICGC;COSMIC	16.613	Up-regulation
Other_IKK_IKBKB_ST	Q9Y4G8	RAPGEF2	O14920	IKBKB	S1022	E1020K	1020	Missense	proximal	-2	no	18.520	18.285	EPSD	TCGA;ICGC;COSMIC	16.613	Down-regulation
Other_IKK_IKBKB_ST	Q9Y4G8	RAPGEF2	O14920	IKBKB	S1022	R1027M	1027	Missense	distal	5	no	18.520	22.597	EPSD	TCGA;ICGC;COSMIC;GDSC;CCLE	16.613	Up-regulation
Other_IKK_IKBKB_ST	Q9Y4G8	RAPGEF2	O14920	IKBKB	S1022	V1024L	1024	Missense	proximal	2	no	18.520	18.117	EPSD	TCGA;ICGC;COSMIC	16.613	Down-regulation
Other_IKK_IKBKB_ST	Q9Y4G8	RAPGEF2	O14920	IKBKB	S1089	K1086Q	1086	Missense	distal	-3	no	27.957	27.445	EPSD	TCGA;ICGC;COSMIC	16.613	Down-regulation
Other_IKK_IKBKB_ST	Q9Y4G8	RAPGEF2	O14920	IKBKB	S1089	L1088I	1088	Missense	proximal	-1	no	27.957	28.735	EPSD	TCGA;ICGC;COSMIC;CCLE	16.613	Up-regulation
Other_IKK_IKBKB_ST	Q9Y4G8	RAPGEF2	O14920	IKBKB	S1095	L1088I	1088	Missense	distal	-7	no	19.879	18.934	EPSD	TCGA;ICGC;COSMIC;CCLE	16.613	Down-regulation
Other_IKK_IKBKB_ST	Q9Y4G8	RAPGEF2	O14920	IKBKB	S1108	S1115C	1115	Missense	distal	7	no	21.384	20.494	EPSD	TCGA;ICGC;COSMIC	16.613	Down-regulation
Other_IKK_IKBKB_ST	Q9Y4G8	RAPGEF2	O14920	IKBKB	S1112	S1115C	1115	Missense	distal	3	no	30.875	27.894	EPSD	TCGA;ICGC;COSMIC	16.613	Down-regulation
Other_IKK_IKBKB_ST	Q9Y4G8	RAPGEF2	O14920	IKBKB	S1115	S1115C	1115	Missense	central	0	yes	18.345	0.000	EPSD	TCGA;ICGC;COSMIC	16.613	Loss
Other_IKK_IKBKB_ST	Q9Y4G8	RAPGEF2	O14920	IKBKB	S1115	P1121S	1121	Missense	distal	6	no	18.345	17.020	EPSD	TCGA;ICGC;COSMIC	16.613	Down-regulation
Other_IKK_IKBKB_ST	Q9Y4G8	RAPGEF2	O14920	IKBKB	S1116	S1115C	1115	Missense	proximal	-1	no	21.270	21.570	EPSD	TCGA;ICGC;COSMIC	16.613	Up-regulation
Other_IKK_IKBKB_ST	Q9Y4G8	RAPGEF2	O14920	IKBKB	S1116	P1121S	1121	Missense	distal	5	no	21.270	21.471	EPSD	TCGA;ICGC;COSMIC	16.613	Up-regulation
Other_IKK_IKBKB_ST	Q9Y4G8	RAPGEF2	O14920	IKBKB	S1120	S1115C	1115	Missense	distal	-5	no	20.426	20.184	EPSD	TCGA;ICGC;COSMIC	16.613	Down-regulation
Other_IKK_IKBKB_ST	Q9Y4G8	RAPGEF2	O14920	IKBKB	S1120	P1121S	1121	Missense	proximal	1	no	20.426	19.364	EPSD	TCGA;ICGC;COSMIC	16.613	Down-regulation
Other_IKK_IKBKB_ST	Q9Y4G8	RAPGEF2	O14920	IKBKB	S1120	S1124Y	1124	Missense	distal	4	no	20.426	16.211	EPSD	TCGA;ICGC;COSMIC	16.613	Loss
Other_IKK_IKBKB_ST	Q9Y4G8	RAPGEF2	O14920	IKBKB	S1124	P1121S	1121	Missense	distal	-3	no	16.612	17.158	EPSD	TCGA;ICGC;COSMIC	16.613	Gain
Other_IKK_IKBKB_ST	Q9Y4G8	RAPGEF2	O14920	IKBKB	S1166	V1163L	1163	Missense	distal	-3	no	19.186	19.105	EPSD	TCGA;ICGC;COSMIC	16.613	Down-regulation
Other_IKK_IKBKB_ST	Q9Y4G8	RAPGEF2	O14920	IKBKB	S1166	R1172H	1172	Missense	distal	6	no	19.186	19.196	EPSD	TCGA;ICGC;COSMIC	16.613	Up-regulation
Other_IKK_IKBKB_ST	Q9Y4G8	RAPGEF2	O14920	IKBKB	S1178	R1172H	1172	Missense	distal	-6	no	16.390	16.936	EPSD	TCGA;ICGC;COSMIC	16.613	Gain
Other_IKK_IKBKB_ST	Q9Y4G8	RAPGEF2	O14920	IKBKB	S1223	S1222F	1222	Missense	proximal	-1	no	23.614	24.070	EPSD	TCGA;ICGC;COSMIC	16.613	Up-regulation
Other_IKK_IKBKB_ST	Q9Y4G8	RAPGEF2	O14920	IKBKB	S1223	T1219A	1219	Missense	distal	-4	no	23.614	23.173	EPSD	TCGA;ICGC;COSMIC	16.613	Down-regulation
Other_IKK_IKBKB_ST	Q9Y4G8	RAPGEF2	O14920	IKBKB	S1223	S1222Y	1222	Missense	proximal	-1	no	23.614	24.206	EPSD	TCGA;ICGC;COSMIC	16.613	Up-regulation
Other_IKK_IKBKB_ST	Q9Y4G8	RAPGEF2	O14920	IKBKB	S1248	C1252S	1252	Missense	distal	4	no	13.250	17.131	EPSD	TCGA;ICGC;COSMIC	16.613	Gain
Other_IKK_IKBKB_ST	Q9Y4G8	RAPGEF2	O14920	IKBKB	S1313	A1320T	1320	Missense	distal	7	no	22.509	21.981	EPSD	TCGA;ICGC	16.613	Down-regulation
Other_IKK_IKBKB_ST	Q9Y4G8	RAPGEF2	O14920	IKBKB	S1313	Q1312K	1312	Missense	proximal	-1	no	22.509	21.962	EPSD	TCGA;ICGC;COSMIC	16.613	Down-regulation
Other_IKK_IKBKB_ST	Q9Y4G8	RAPGEF2	O14920	IKBKB	S1322	A1327V	1327	Missense	distal	5	no	18.220	16.498	EPSD	TCGA;ICGC;COSMIC	16.613	Loss
Other_IKK_IKBKB_ST	Q9Y4G8	RAPGEF2	O14920	IKBKB	S1322	A1320T	1320	Missense	proximal	-2	no	18.220	18.437	EPSD	TCGA;ICGC	16.613	Up-regulation
Other_IKK_IKBKB_ST	Q9Y4G8	RAPGEF2	O14920	IKBKB	S1325	A1327V	1327	Missense	proximal	2	no	16.907	16.903	EPSD	TCGA;ICGC;COSMIC	16.613	Down-regulation
Other_IKK_IKBKB_ST	Q9Y4G8	RAPGEF2	O14920	IKBKB	S1325	A1320T	1320	Missense	distal	-5	no	16.907	16.973	EPSD	TCGA;ICGC	16.613	Up-regulation
Other_IKK_IKBKB_ST	P35568	IRS1	O14920	IKBKB	S270	E263K	263	Missense	distal	-7	no	16.872	16.318	EPSD	TCGA;ICGC;COSMIC	16.613	Loss
Other_IKK_IKBKB_ST	P35568	IRS1	O14920	IKBKB	S270	K269N	269	Missense	proximal	-1	no	16.872	16.819	EPSD	TCGA;ICGC;COSMIC	16.613	Down-regulation
Other_IKK_IKBKB_ST	P35568	IRS1	O14920	IKBKB	S270	P266S	266	Missense	distal	-4	no	16.872	20.396	EPSD	TCGA;ICGC;COSMIC	16.613	Up-regulation
Other_IKK_IKBKB_ST	P35568	IRS1	O14920	IKBKB	S270	C276F	276	Missense	distal	6	no	16.872	17.243	EPSD	TCGA;ICGC;COSMIC	16.613	Up-regulation
Other_IKK_IKBKB_ST	P35568	IRS1	O14920	IKBKB	S270	N275S	275	Missense	distal	5	no	16.872	18.326	EPSD	TCGA;ICGC;COSMIC	16.613	Up-regulation
Other_IKK_IKBKB_ST	P35568	IRS1	O14920	IKBKB	S273	P266S	266	Missense	distal	-7	no	16.209	17.482	EPSD	TCGA;ICGC;COSMIC	16.613	Gain
Other_IKK_IKBKB_ST	P35568	IRS1	O14920	IKBKB	S274	K269N	269	Missense	distal	-5	no	20.210	20.512	EPSD	TCGA;ICGC;COSMIC	16.613	Up-regulation
Other_IKK_IKBKB_ST	P35568	IRS1	O14920	IKBKB	S274	C276F	276	Missense	proximal	2	no	20.210	20.298	EPSD	TCGA;ICGC;COSMIC	16.613	Up-regulation
Other_IKK_IKBKB_ST	P35568	IRS1	O14920	IKBKB	S274	N275S	275	Missense	proximal	1	no	20.210	19.495	EPSD	TCGA;ICGC;COSMIC	16.613	Down-regulation
Other_IKK_IKBKB_ST	P35568	IRS1	O14920	IKBKB	S281	C276F	276	Missense	distal	-5	no	20.858	20.861	EPSD	TCGA;ICGC;COSMIC	16.613	Up-regulation
Other_IKK_IKBKB_ST	P35568	IRS1	O14920	IKBKB	S281	R285H	285	Missense	distal	4	no	20.858	19.953	EPSD	TCGA;ICGC;COSMIC	16.613	Down-regulation
Other_IKK_IKBKB_ST	P35568	IRS1	O14920	IKBKB	S281	N275S	275	Missense	distal	-6	no	20.858	20.734	EPSD	TCGA;ICGC;COSMIC	16.613	Down-regulation
Other_IKK_IKBKB_ST	P35568	IRS1	O14920	IKBKB	S281	R285C	285	Missense	distal	4	no	20.858	19.542	EPSD	TCGA;ICGC;COSMIC	16.613	Down-regulation
Other_IKK_IKBKB_ST	P35568	IRS1	O14920	IKBKB	S312	A314G	314	Missense	proximal	2	no	24.537	23.615	PhosphoSitePlus	TCGA;ICGC;COSMIC	16.613	Down-regulation
Other_IKK_IKBKB_ST	P35568	IRS1	O14920	IKBKB	S341	T335I	335	Missense	distal	-6	no	18.216	17.107	EPSD	TCGA;ICGC;COSMIC	16.613	Down-regulation
Other_IKK_IKBKB_ST	P35568	IRS1	O14920	IKBKB	S341	R338H	338	Missense	distal	-3	no	18.216	17.922	EPSD	TCGA;ICGC;COSMIC	16.613	Down-regulation
Other_IKK_IKBKB_ST	P35568	IRS1	O14920	IKBKB	S341	R338C	338	Missense	distal	-3	no	18.216	17.635	EPSD	TCGA;ICGC;COSMIC	16.613	Down-regulation
Other_IKK_IKBKB_ST	P35568	IRS1	O14920	IKBKB	S341	P346H	346	Missense	distal	5	no	18.216	17.069	EPSD	TCGA;ICGC	16.613	Down-regulation
Other_IKK_IKBKB_ST	P35568	IRS1	O14920	IKBKB	S345	R338H	338	Missense	distal	-7	no	16.759	15.564	EPSD	TCGA;ICGC;COSMIC	16.613	Loss
Other_IKK_IKBKB_ST	P35568	IRS1	O14920	IKBKB	S345	R338C	338	Missense	distal	-7	no	16.759	14.942	EPSD	TCGA;ICGC;COSMIC	16.613	Loss
Other_IKK_IKBKB_ST	P35568	IRS1	O14920	IKBKB	S345	P346H	346	Missense	proximal	1	no	16.759	16.680	EPSD	TCGA;ICGC	16.613	Down-regulation
Other_IKK_IKBKB_ST	P35568	IRS1	O14920	IKBKB	S380	R381H	381	Missense	proximal	1	no	18.081	18.671	EPSD	TCGA	16.613	Up-regulation
Other_IKK_IKBKB_ST	P35568	IRS1	O14920	IKBKB	S380	R373C	373	Missense	distal	-7	no	18.081	16.264	EPSD	TCGA;ICGC;COSMIC	16.613	Loss
Other_IKK_IKBKB_ST	P35568	IRS1	O14920	IKBKB	S380	P384H	384	Missense	distal	4	no	18.081	16.811	EPSD	TCGA;ICGC;COSMIC	16.613	Down-regulation
Other_IKK_IKBKB_ST	P35568	IRS1	O14920	IKBKB	S380	P378S	378	Missense	proximal	-2	no	18.081	17.194	EPSD	TCGA;ICGC;COSMIC	16.613	Down-regulation
Other_IKK_IKBKB_ST	P35568	IRS1	O14920	IKBKB	S398	S395C	395	Missense	distal	-3	no	23.451	23.030	EPSD	TCGA;ICGC;COSMIC	16.613	Down-regulation
Other_IKK_IKBKB_ST	P35568	IRS1	O14920	IKBKB	S402	S395C	395	Missense	distal	-7	no	19.297	17.949	EPSD	TCGA;ICGC;COSMIC	16.613	Down-regulation
Other_IKK_IKBKB_ST	P35568	IRS1	O14920	IKBKB	S463	G469C	469	Missense	distal	6	no	25.203	25.248	EPSD	TCGA;ICGC;COSMIC	16.613	Up-regulation
Other_IKK_IKBKB_ST	P35568	IRS1	O14920	IKBKB	S463	E461G	461	Missense	proximal	-2	no	25.203	26.272	EPSD	TCGA;ICGC;COSMIC	16.613	Up-regulation
Other_IKK_IKBKB_ST	P35568	IRS1	O14920	IKBKB	S853	A856T	856	Missense	distal	3	no	16.533	16.982	EPSD	TCGA;ICGC;COSMIC	16.613	Gain
Other_IKK_IKBKB_ST	P35568	IRS1	O14920	IKBKB	S869	E876Q	876	Missense	distal	7	no	19.349	18.779	EPSD	TCGA;ICGC;COSMIC	16.613	Down-regulation
Other_IKK_IKBKB_ST	P35568	IRS1	O14920	IKBKB	S985	R986W	986	Missense	proximal	1	no	16.895	18.180	EPSD	TCGA;ICGC;COSMIC;GDSC;CCLE	16.613	Up-regulation
Other_IKK_IKBKB_ST	P35568	IRS1	O14920	IKBKB	S1000	S1005L	1005	Missense	distal	5	no	18.616	18.692	EPSD	TCGA;ICGC	16.613	Up-regulation
Other_IKK_IKBKB_ST	P35568	IRS1	O14920	IKBKB	S1011	R1016Q	1016	Missense	distal	5	no	15.726	17.447	EPSD	TCGA;ICGC;COSMIC	16.613	Gain
Other_IKK_IKBKB_ST	P35568	IRS1	O14920	IKBKB	S1043	P1047S	1047	Missense	distal	4	no	25.354	27.554	EPSD	TCGA;ICGC;COSMIC	16.613	Up-regulation
Other_IKK_IKBKB_ST	P35568	IRS1	O14920	IKBKB	S1078	R1081H	1081	Missense	distal	3	no	20.834	20.955	EPSD	TCGA;ICGC;COSMIC	16.613	Up-regulation
Other_IKK_IKBKB_ST	P35568	IRS1	O14920	IKBKB	S1109	S1109C	1109	Missense	central	0	yes	18.803	0.000	EPSD	TCGA;ICGC;COSMIC	16.613	Loss
Other_IKK_IKBKB_ST	P35568	IRS1	O14920	IKBKB	S1131	A1124V	1124	Missense	distal	-7	no	16.828	13.696	EPSD	TCGA;ICGC;COSMIC	16.613	Loss
Other_IKK_IKBKB_ST	P35568	IRS1	O14920	IKBKB	S1131	S1133N	1133	Missense	proximal	2	no	16.828	16.793	EPSD	TCGA;ICGC	16.613	Down-regulation
Other_IKK_IKBKB_ST	P35568	IRS1	O14920	IKBKB	S1216	S1223G	1223	Missense	distal	7	no	20.156	19.282	EPSD	TCGA;ICGC;COSMIC	16.613	Down-regulation
Other_IKK_IKBKB_ST	P35568	IRS1	O14920	IKBKB	T1219	S1223G	1223	Missense	distal	4	no	16.616	11.715	EPSD	TCGA;ICGC;COSMIC	16.613	Loss
Other_IKK_IKBKB_ST	P35568	IRS1	O14920	IKBKB	S1222	S1223G	1223	Missense	proximal	1	no	28.475	29.982	EPSD	TCGA;ICGC;COSMIC	16.613	Up-regulation
Other_IKK_IKBKB_ST	P35568	IRS1	O14920	IKBKB	S1223	S1223G	1223	Missense	central	0	yes	16.694	0.000	EPSD	TCGA;ICGC;COSMIC	16.613	Loss
Other_IKK_IKBKB_ST	P35568	IRS1	O14920	IKBKB	S1227	S1223G	1223	Missense	distal	-4	no	23.038	16.762	EPSD	TCGA;ICGC;COSMIC	16.613	Down-regulation
Other_IKK_IKBKB_ST	P35568	IRS1	O14920	IKBKB	S1227	S1233G	1233	Missense	distal	6	no	23.038	24.715	EPSD	TCGA;ICGC;COSMIC	16.613	Up-regulation
Other_IKK_IKBKB_ST	P35568	IRS1	O14920	IKBKB	S1231	S1233G	1233	Missense	proximal	2	no	27.300	26.663	EPSD	TCGA;ICGC;COSMIC	16.613	Down-regulation
Other_IKK_IKBKB_ST	Q7Z434	MAVS	O14920	IKBKB	S192	P189S	189	Missense	distal	-3	no	23.226	23.773	EPSD	TCGA;ICGC;COSMIC	16.613	Up-regulation
Other_IKK_IKBKB_ST	Q7Z434	MAVS	O14920	IKBKB	S217	S217F	217	Missense	central	0	yes	21.264	0.000	EPSD	TCGA;ICGC;COSMIC	16.613	Loss
Other_IKK_IKBKB_ST	Q7Z434	MAVS	O14920	IKBKB	S217	P223L	223	Missense	distal	6	no	21.264	21.147	EPSD	TCGA;ICGC;COSMIC	16.613	Down-regulation
Other_IKK_IKBKB_ST	Q7Z434	MAVS	O14920	IKBKB	S226	P223L	223	Missense	distal	-3	no	16.775	16.914	EPSD	TCGA;ICGC;COSMIC	16.613	Up-regulation
Other_IKK_IKBKB_ST	Q7Z434	MAVS	O14920	IKBKB	S226	R232H	232	Missense	distal	6	no	16.775	16.786	EPSD	TCGA;ICGC;COSMIC	16.613	Up-regulation
Other_IKK_IKBKB_ST	Q7Z434	MAVS	O14920	IKBKB	S253	S256P	256	Missense	distal	3	no	20.346	19.010	EPSD	TCGA;ICGC;COSMIC	16.613	Down-regulation
Other_IKK_IKBKB_ST	Q7Z434	MAVS	O14920	IKBKB	S256	S256P	256	Missense	central	0	yes	21.111	0.000	EPSD	TCGA;ICGC;COSMIC	16.613	Loss
Other_IKK_IKBKB_ST	Q7Z434	MAVS	O14920	IKBKB	S263	S256P	256	Missense	distal	-7	no	20.310	19.037	EPSD	TCGA;ICGC;COSMIC	16.613	Down-regulation
Other_IKK_IKBKB_ST	Q7Z434	MAVS	O14920	IKBKB	S275	I281V	281	Missense	distal	6	no	19.636	19.842	EPSD	TCGA;ICGC;COSMIC	16.613	Up-regulation
Other_IKK_IKBKB_ST	Q7Z434	MAVS	O14920	IKBKB	S366	V372A	372	Missense	distal	6	no	16.936	16.141	EPSD	TCGA;ICGC;COSMIC	16.613	Loss
Other_IKK_IKBKB_ST	Q7Z434	MAVS	O14920	IKBKB	S416	E417Q	417	Missense	proximal	1	no	25.672	26.006	EPSD	TCGA;ICGC;COSMIC	16.613	Up-regulation
Other_IKK_IKBKB_ST	Q7Z434	MAVS	O14920	IKBKB	S416	V423M	423	Missense	distal	7	no	25.672	27.405	EPSD	TCGA;ICGC;COSMIC	16.613	Up-regulation
Other_IKK_IKBKB_ST	Q7Z434	MAVS	O14920	IKBKB	S416	L414I	414	Missense	proximal	-2	no	25.672	25.204	EPSD	TCGA;ICGC;COSMIC	16.613	Down-regulation
Other_IKK_IKBKB_ST	Q7Z434	MAVS	O14920	IKBKB	S416	G413D	413	Missense	distal	-3	no	25.672	25.684	EPSD	TCGA;ICGC;COSMIC	16.613	Up-regulation
Other_IKK_IKBKB_ST	Q7Z434	MAVS	O14920	IKBKB	S419	V423M	423	Missense	distal	4	no	12.441	20.014	EPSD	TCGA;ICGC;COSMIC	16.613	Gain
Other_IKK_IKBKB_ST	Q7Z434	MAVS	O14920	IKBKB	S475	V470A	470	Missense	distal	-5	no	16.411	16.760	EPSD	TCGA;ICGC;COSMIC	16.613	Gain
Other_IKK_IKBKB_ST	Q7Z434	MAVS	O14920	IKBKB	S475	H469N	469	Missense	distal	-6	no	16.411	16.647	EPSD	TCGA;ICGC;COSMIC	16.613	Gain
Other_IKK_IKBKB_ST	Q16875	PFKFB3	O14920	IKBKB	S269	G270D	270	Missense	proximal	1	no	25.228	23.978	PhosphoSitePlus	TCGA;COSMIC	16.613	Down-regulation
Other_IKK_IKBKB_ST	Q16875	PFKFB3	O14920	IKBKB	S269	S273N	273	Missense	distal	4	no	25.228	22.362	PhosphoSitePlus	TCGA;ICGC;COSMIC	16.613	Down-regulation
Other_IKK_IKBKB_ST	Q16875	PFKFB3	O14920	IKBKB	S269	G275C	275	Missense	distal	6	no	25.228	25.273	PhosphoSitePlus	TCGA;ICGC;COSMIC	16.613	Up-regulation
Other_IKK_IKBKB_ST	Q16875	PFKFB3	O14920	IKBKB	S280	S273N	273	Missense	distal	-7	no	19.662	20.854	EPSD	TCGA;ICGC;COSMIC	16.613	Up-regulation
Other_IKK_IKBKB_ST	Q16875	PFKFB3	O14920	IKBKB	S280	G275C	275	Missense	distal	-5	no	19.662	19.549	EPSD	TCGA;ICGC;COSMIC	16.613	Down-regulation
Other_IKK_IKBKB_ST	Q16875	PFKFB3	O14920	IKBKB	S446	R443W	443	Missense	distal	-3	no	22.517	21.354	EPSD	TCGA;ICGC;COSMIC;CCLE	16.613	Down-regulation
Other_IKK_IKBKB_ST	Q16875	PFKFB3	O14920	IKBKB	S461	S461C	461	Missense	central	0	yes	17.376	0.000	EPSD	TCGA;COSMIC	16.613	Loss
Other_IKK_IKBKB_ST	Q16875	PFKFB3	O14920	IKBKB	S461	P464L	464	Missense	distal	3	no	17.376	15.760	EPSD	TCGA;COSMIC	16.613	Loss
Other_IKK_IKBKB_ST	Q16875	PFKFB3	O14920	IKBKB	S461	N460Y	460	Missense	proximal	-1	no	17.376	18.112	EPSD	TCGA;COSMIC	16.613	Up-regulation
Other_IKK_IKBKB_ST	Q16875	PFKFB3	O14920	IKBKB	S467	S461C	461	Missense	distal	-6	no	21.267	20.080	EPSD	TCGA;COSMIC	16.613	Down-regulation
Other_IKK_IKBKB_ST	Q16875	PFKFB3	O14920	IKBKB	S467	P464L	464	Missense	distal	-3	no	21.267	21.405	EPSD	TCGA;COSMIC	16.613	Up-regulation
Other_IKK_IKBKB_ST	Q16875	PFKFB3	O14920	IKBKB	S467	N460Y	460	Missense	distal	-7	no	21.267	17.601	EPSD	TCGA;COSMIC	16.613	Down-regulation
Other_IKK_IKBKB_ST	Q16875	PFKFB3	O14920	IKBKB	S467	E469K	469	Missense	proximal	2	no	21.267	21.389	EPSD	TCGA;COSMIC	16.613	Up-regulation
Other_IKK_IKBKB_ST	Q16875	PFKFB3	O14920	IKBKB	S478	R475G	475	Missense	distal	-3	no	17.623	17.196	EPSD	TCGA;COSMIC	16.613	Down-regulation
Other_IKK_IKBKB_ST	Q16875	PFKFB3	O14920	IKBKB	S485	A489T	489	Missense	distal	4	no	21.721	20.769	EPSD	TCGA;COSMIC	16.613	Down-regulation
Other_IKK_IKBKB_ST	Q16875	PFKFB3	O14920	IKBKB	S485	S492N	492	Missense	distal	7	no	21.721	20.989	EPSD	TCGA;COSMIC	16.613	Down-regulation
Other_IKK_IKBKB_ST	P20749	BCL3	O14920	IKBKB	S382	E384K	384	Missense	proximal	2	no	16.631	16.753	EPSD	TCGA;ICGC;COSMIC	16.613	Up-regulation
Other_IKK_IKBKB_ST	P20749	BCL3	O14920	IKBKB	S386	E384K	384	Missense	proximal	-2	no	18.533	18.298	EPSD	TCGA;ICGC;COSMIC	16.613	Down-regulation
Other_IKK_IKBKB_ST	P20749	BCL3	O14920	IKBKB	S402	S396F	396	Missense	distal	-6	no	16.899	15.750	EPSD	TCGA;ICGC;COSMIC	16.613	Loss
Other_IKK_IKBKB_ST	P20749	BCL3	O14920	IKBKB	S402	Q405K	405	Missense	distal	3	no	16.899	18.778	EPSD	TCGA;ICGC;COSMIC	16.613	Up-regulation
Other_IKK_IKBKB_ST	P20749	BCL3	O14920	IKBKB	S402	P408H	408	Missense	distal	6	no	16.899	16.208	EPSD	TCGA;ICGC	16.613	Loss
Other_IKK_IKBKB_ST	P20749	BCL3	O14920	IKBKB	S402	P407T	407	Missense	distal	5	no	16.899	16.378	EPSD	TCGA;ICGC;COSMIC	16.613	Loss
Other_IKK_IKBKB_ST	Q96CV9	OPTN	O14920	IKBKB	S7	E11K	11	Missense	distal	4	no	20.135	17.277	EPSD	TCGA;ICGC;COSMIC	16.613	Down-regulation
Other_IKK_IKBKB_ST	Q96CV9	OPTN	O14920	IKBKB	S7	L6F	6	Missense	proximal	-1	no	20.135	20.744	EPSD	TCGA;ICGC;COSMIC	16.613	Up-regulation
Other_IKK_IKBKB_ST	Q96CV9	OPTN	O14920	IKBKB	S90	R96C	96	Missense	distal	6	no	15.724	16.822	EPSD	TCGA;ICGC;COSMIC	16.613	Gain
Other_IKK_IKBKB_ST	Q96CV9	OPTN	O14920	IKBKB	S162	N169S	169	Missense	distal	7	no	22.256	22.989	EPSD	TCGA	16.613	Up-regulation
Other_IKK_IKBKB_ST	Q96CV9	OPTN	O14920	IKBKB	S171	N169S	169	Missense	proximal	-2	no	18.566	18.649	EPSD	TCGA	16.613	Up-regulation
Other_IKK_IKBKB_ST	Q96CV9	OPTN	O14920	IKBKB	S171	D176Y	176	Missense	distal	5	no	18.566	16.448	EPSD	TCGA;ICGC;COSMIC	16.613	Loss
Other_IKK_IKBKB_ST	Q96CV9	OPTN	O14920	IKBKB	S171	E175Q	175	Missense	distal	4	no	18.566	16.060	EPSD	TCGA;ICGC;COSMIC	16.613	Loss
Other_IKK_IKBKB_ST	Q96CV9	OPTN	O14920	IKBKB	S171	F178V	178	Missense	distal	7	no	18.566	18.316	EPSD	TCGA;ICGC;COSMIC	16.613	Down-regulation
Other_IKK_IKBKB_ST	Q96CV9	OPTN	O14920	IKBKB	S173	N169S	169	Missense	distal	-4	no	16.933	20.639	EPSD	TCGA	16.613	Up-regulation
Other_IKK_IKBKB_ST	Q96CV9	OPTN	O14920	IKBKB	S173	D176Y	176	Missense	distal	3	no	16.933	15.772	EPSD	TCGA;ICGC;COSMIC	16.613	Loss
Other_IKK_IKBKB_ST	Q96CV9	OPTN	O14920	IKBKB	S173	E175Q	175	Missense	proximal	2	no	16.933	16.391	EPSD	TCGA;ICGC;COSMIC	16.613	Loss
Other_IKK_IKBKB_ST	Q96CV9	OPTN	O14920	IKBKB	S173	F178V	178	Missense	distal	5	no	16.933	17.473	EPSD	TCGA;ICGC;COSMIC	16.613	Up-regulation
Other_IKK_IKBKB_ST	Q96CV9	OPTN	O14920	IKBKB	S191	A184S	184	Missense	distal	-7	no	17.322	16.525	EPSD	TCGA;ICGC;COSMIC	16.613	Loss
Other_IKK_IKBKB_ST	Q96CV9	OPTN	O14920	IKBKB	S191	A184D	184	Missense	distal	-7	no	17.322	16.877	EPSD	TCGA;ICGC	16.613	Down-regulation
Other_IKK_IKBKB_ST	Q96CV9	OPTN	O14920	IKBKB	S234	T232I	232	Missense	proximal	-2	no	20.993	21.525	EPSD	TCGA;ICGC;COSMIC	16.613	Up-regulation
Other_IKK_IKBKB_ST	Q96CV9	OPTN	O14920	IKBKB	S234	L237P	237	Missense	distal	3	no	20.993	22.609	EPSD	TCGA;ICGC;COSMIC	16.613	Up-regulation
Other_IKK_IKBKB_ST	Q96CV9	OPTN	O14920	IKBKB	S269	R271C	271	Missense	proximal	2	no	28.400	28.196	EPSD	TCGA;ICGC;COSMIC	16.613	Down-regulation
Other_IKK_IKBKB_ST	Q96CV9	OPTN	O14920	IKBKB	S269	E273Q	273	Missense	distal	4	no	28.400	25.894	EPSD	TCGA;ICGC;COSMIC	16.613	Down-regulation
Other_IKK_IKBKB_ST	Q96CV9	OPTN	O14920	IKBKB	S281	E279Q	279	Missense	proximal	-2	no	16.909	17.447	EPSD	TCGA;ICGC;COSMIC	16.613	Up-regulation
Other_IKK_IKBKB_ST	Q96CV9	OPTN	O14920	IKBKB	S297	E293K	293	Missense	distal	-4	no	23.857	21.399	EPSD	TCGA;ICGC;COSMIC	16.613	Down-regulation
Other_IKK_IKBKB_ST	Q96CV9	OPTN	O14920	IKBKB	S297	G296E	296	Missense	proximal	-1	no	23.857	23.435	EPSD	TCGA;ICGC;COSMIC	16.613	Down-regulation
Other_IKK_IKBKB_ST	Q96CV9	OPTN	O14920	IKBKB	S297	E293Q	293	Missense	distal	-4	no	23.857	18.994	EPSD	TCGA;ICGC;COSMIC	16.613	Down-regulation
Other_IKK_IKBKB_ST	Q96CV9	OPTN	O14920	IKBKB	S308	E315K	315	Missense	distal	7	no	21.406	21.109	EPSD	TCGA;ICGC;COSMIC	16.613	Down-regulation
Other_IKK_IKBKB_ST	Q96CV9	OPTN	O14920	IKBKB	S308	E312K	312	Missense	distal	4	no	21.406	18.547	EPSD	TCGA;ICGC;COSMIC	16.613	Down-regulation
Other_IKK_IKBKB_ST	Q96CV9	OPTN	O14920	IKBKB	S308	E315D	315	Missense	distal	7	no	21.406	20.307	EPSD	TCGA;ICGC;COSMIC	16.613	Down-regulation
Other_IKK_IKBKB_ST	Q96CV9	OPTN	O14920	IKBKB	S308	E312A	312	Missense	distal	4	no	21.406	16.919	EPSD	TCGA;ICGC;COSMIC	16.613	Down-regulation
Other_IKK_IKBKB_ST	Q96CV9	OPTN	O14920	IKBKB	S342	E338K	338	Missense	distal	-4	no	19.486	17.028	EPSD	TCGA;ICGC;COSMIC	16.613	Down-regulation
Other_IKK_IKBKB_ST	Q96CV9	OPTN	O14920	IKBKB	S342	L337F	337	Missense	distal	-5	no	19.486	19.305	EPSD	TCGA;ICGC;COSMIC	16.613	Down-regulation
Other_IKK_IKBKB_ST	Q96CV9	OPTN	O14920	IKBKB	S473	A480S	480	Missense	distal	7	no	19.936	20.016	EPSD	TCGA;ICGC	16.613	Up-regulation
Other_IKK_IKBKB_ST	Q96CV9	OPTN	O14920	IKBKB	S513	G509R	509	Missense	distal	-4	no	22.426	26.391	PhosphoSitePlus	TCGA;ICGC;COSMIC	16.613	Up-regulation
Other_IKK_IKBKB_ST	O43524	FOXO3	O14920	IKBKB	S200	G205S	205	Missense	distal	5	no	16.770	20.082	EPSD	TCGA;ICGC;COSMIC	16.613	Up-regulation
Other_IKK_IKBKB_ST	O43524	FOXO3	O14920	IKBKB	S203	S209F	209	Missense	distal	6	no	18.773	20.866	EPSD	TCGA;ICGC	16.613	Up-regulation
Other_IKK_IKBKB_ST	O43524	FOXO3	O14920	IKBKB	S203	G205S	205	Missense	proximal	2	no	18.773	19.410	EPSD	TCGA;ICGC;COSMIC	16.613	Up-regulation
Other_IKK_IKBKB_ST	O43524	FOXO3	O14920	IKBKB	S203	S209Y	209	Missense	distal	6	no	18.773	20.738	EPSD	TCGA;ICGC;COSMIC	16.613	Up-regulation
Other_IKK_IKBKB_ST	O43524	FOXO3	O14920	IKBKB	S297	L303M	303	Missense	distal	6	no	19.792	19.018	EPSD	TCGA;ICGC	16.613	Down-regulation
Other_IKK_IKBKB_ST	O43524	FOXO3	O14920	IKBKB	S297	S299I	299	Missense	proximal	2	no	19.792	19.507	EPSD	TCGA;ICGC;COSMIC	16.613	Down-regulation
Other_IKK_IKBKB_ST	O43524	FOXO3	O14920	IKBKB	S297	R298C	298	Missense	proximal	1	no	19.792	20.530	EPSD	TCGA;ICGC	16.613	Up-regulation
Other_IKK_IKBKB_ST	O43524	FOXO3	O14920	IKBKB	S297	G293D	293	Missense	distal	-4	no	19.792	26.163	EPSD	TCGA;ICGC;COSMIC	16.613	Up-regulation
Other_IKK_IKBKB_ST	O43524	FOXO3	O14920	IKBKB	S321	R323L	323	Missense	proximal	2	no	17.349	17.332	EPSD	TCGA;ICGC;COSMIC	16.613	Down-regulation
Other_IKK_IKBKB_ST	O43524	FOXO3	O14920	IKBKB	S321	S315F	315	Missense	distal	-6	no	17.349	16.200	EPSD	TCGA;ICGC;COSMIC	16.613	Loss
Other_IKK_IKBKB_ST	O43524	FOXO3	O14920	IKBKB	S321	M328I	328	Missense	distal	7	no	17.349	15.939	EPSD	TCGA;ICGC;COSMIC	16.613	Loss
Other_IKK_IKBKB_ST	O43524	FOXO3	O14920	IKBKB	S425	L423M	423	Missense	proximal	-2	no	21.730	20.807	EPSD	TCGA;ICGC	16.613	Down-regulation
Other_IKK_IKBKB_ST	O43524	FOXO3	O14920	IKBKB	S425	S425F	425	Missense	central	0	yes	21.730	0.000	EPSD	TCGA;ICGC;COSMIC	16.613	Loss
Other_IKK_IKBKB_ST	O43524	FOXO3	O14920	IKBKB	S432	G436R	436	Missense	distal	4	no	16.803	19.139	EPSD	TCGA;ICGC;COSMIC;GDSC;CCLE	16.613	Up-regulation
Other_IKK_IKBKB_ST	O43524	FOXO3	O14920	IKBKB	S432	S425F	425	Missense	distal	-7	no	16.803	14.621	EPSD	TCGA;ICGC;COSMIC	16.613	Loss
Other_IKK_IKBKB_ST	O43524	FOXO3	O14920	IKBKB	S432	V434M	434	Missense	proximal	2	no	16.803	17.475	EPSD	TCGA;ICGC;COSMIC	16.613	Up-regulation
Other_IKK_IKBKB_ST	O43524	FOXO3	O14920	IKBKB	S438	V434M	434	Missense	distal	-4	no	16.337	27.099	EPSD	TCGA;ICGC;COSMIC	16.613	Gain
Other_IKK_IKBKB_ST	O43524	FOXO3	O14920	IKBKB	S555	S560I	560	Missense	distal	5	no	18.413	16.060	EPSD	TCGA;ICGC;COSMIC	16.613	Loss
Other_IKK_IKBKB_ST	O43524	FOXO3	O14920	IKBKB	S555	S553Y	553	Missense	proximal	-2	no	18.413	18.971	EPSD	TCGA;ICGC;COSMIC	16.613	Up-regulation
Other_IKK_IKBKB_ST	O43524	FOXO3	O14920	IKBKB	S564	S560I	560	Missense	distal	-4	no	18.329	11.210	EPSD	TCGA;ICGC;COSMIC	16.613	Loss
Other_IKK_IKBKB_ST	O43524	FOXO3	O14920	IKBKB	S588	D585A	585	Missense	distal	-3	no	17.181	17.567	EPSD	TCGA;ICGC;COSMIC	16.613	Up-regulation
Other_IKK_IKBKB_ST	O43524	FOXO3	O14920	IKBKB	S644	N650S	650	Missense	distal	6	no	22.630	21.222	PhosphoSitePlus	TCGA;ICGC;COSMIC	16.613	Down-regulation
Other_IKK_IKBKB_ST	Q04864	REL	O14920	IKBKB	S422	R421C	421	Missense	proximal	-1	no	17.220	17.354	EPSD	TCGA;ICGC;COSMIC	16.613	Up-regulation
Other_IKK_IKBKB_ST	Q04864	REL	O14920	IKBKB	S422	A416V	416	Missense	distal	-6	no	17.220	15.512	EPSD	TCGA;ICGC;COSMIC	16.613	Loss
Other_IKK_IKBKB_ST	Q04864	REL	O14920	IKBKB	S422	T425A	425	Missense	distal	3	no	17.220	16.772	EPSD	TCGA;ICGC;COSMIC	16.613	Down-regulation
Other_IKK_IKBKB_ST	Q04864	REL	O14920	IKBKB	S422	P427S	427	Missense	distal	5	no	17.220	17.421	EPSD	TCGA;ICGC;COSMIC	16.613	Up-regulation
Other_IKK_IKBKB_ST	Q04864	REL	O14920	IKBKB	S503	D504N	504	Missense	proximal	1	no	16.245	16.703	EPSD	TCGA;ICGC;COSMIC	16.613	Gain
Other_IKK_IKBKB_ST	Q04864	REL	O14920	IKBKB	S516	N521T	521	Missense	distal	5	no	18.457	19.189	EPSD	TCGA;ICGC	16.613	Up-regulation
Other_IKK_IKBKB_ST	Q04864	REL	O14920	IKBKB	S526	D532Y	532	Missense	distal	6	no	17.352	18.555	EPSD	TCGA;ICGC	16.613	Up-regulation
Other_IKK_IKBKB_ST	Q04864	REL	O14920	IKBKB	S526	N521T	521	Missense	distal	-5	no	17.352	17.117	EPSD	TCGA;ICGC	16.613	Down-regulation
Other_IKK_IKBKB_ST	Q04864	REL	O14920	IKBKB	S526	N525D	525	Missense	proximal	-1	no	17.352	17.798	EPSD	TCGA;ICGC;COSMIC	16.613	Up-regulation
Other_IKK_IKBKB_ST	Q13568	IRF5	O14920	IKBKB	S156	M153L	153	Missense	distal	-3	no	18.586	18.006	EPSD	TCGA;ICGC;COSMIC	16.613	Down-regulation
Other_IKK_IKBKB_ST	Q13568	IRF5	O14920	IKBKB	S156	S158N	158	Missense	proximal	2	no	18.586	18.552	EPSD	TCGA;ICGC;COSMIC	16.613	Down-regulation
Other_IKK_IKBKB_ST	Q13568	IRF5	O14920	IKBKB	S156	L157M	157	Missense	proximal	1	no	18.586	17.641	EPSD	TCGA;ICGC;COSMIC	16.613	Down-regulation
CAMK_MAPKAPK_MNK_MKNK1_ST	Q9NP80	PNPLA8	Q9BUB5	MKNK1	S106	K113N	113	Missense	distal	7	no	10.135	10.102	EPSD	TCGA;ICGC;COSMIC	8.316	Down-regulation
CAMK_MAPKAPK_MNK_MKNK1_ST	Q9NP80	PNPLA8	Q9BUB5	MKNK1	S106	S102P	102	Missense	distal	-4	no	10.135	9.503	EPSD	TCGA;ICGC;COSMIC	8.316	Down-regulation
CAMK_MAPKAPK_MNK_MKNK1_ST	Q9NP80	PNPLA8	Q9BUB5	MKNK1	S511	R507Q	507	Missense	distal	-4	no	14.163	13.772	PhosphoSitePlus	TCGA;ICGC;COSMIC	8.316	Down-regulation
CAMK_MAPKAPK_MNK_MKNK1_ST	P23246	SFPQ	Q9BUB5	MKNK1	S8	S2F	2	Missense	distal	-6	no	12.117	12.104	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	8.316	Down-regulation
CAMK_MAPKAPK_MNK_MKNK1_ST	P23246	SFPQ	Q9BUB5	MKNK1	S283	R287K	287	Missense	distal	4	no	14.701	13.283	PhosphoSitePlus;EPSD	TCGA	8.316	Down-regulation
CAMK_MAPKAPK_MNK_MKNK1_ST	P23246	SFPQ	Q9BUB5	MKNK1	S283	S283C	283	Missense	central	0	yes	14.701	0.000	PhosphoSitePlus;EPSD	TCGA;ICGC;COSMIC	8.316	Loss
CAMK_MAPKAPK_MNK_MKNK1_ST	P23246	SFPQ	Q9BUB5	MKNK1	S283	E290K	290	Missense	distal	7	no	14.701	14.668	PhosphoSitePlus;EPSD	TCGA;ICGC;COSMIC	8.316	Down-regulation
CAMK_MAPKAPK_MNK_MKNK1_ST	P23246	SFPQ	Q9BUB5	MKNK1	S379	N384S	384	Missense	distal	5	no	9.135	9.295	EPSD	TCGA;ICGC;COSMIC	8.316	Up-regulation
CAMK_MAPKAPK_MNK_MKNK1_ST	P23246	SFPQ	Q9BUB5	MKNK1	S379	E385K	385	Missense	distal	6	no	9.135	9.820	EPSD	TCGA;ICGC;COSMIC	8.316	Up-regulation
CAMK_MAPKAPK_MNK_MKNK1_ST	P09651	HNRNPA1	Q9BUB5	MKNK1	S6	P10S	10	Missense	distal	4	no	6.687	10.157	EPSD	TCGA;ICGC;COSMIC	8.316	Gain
CAMK_MAPKAPK_MNK_MKNK1_ST	P09651	HNRNPA1	Q9BUB5	MKNK1	S91	R97T	97	Missense	distal	6	no	9.416	8.988	EPSD	TCGA;ICGC;COSMIC	8.316	Down-regulation
CAMK_MAPKAPK_MNK_MKNK1_ST	P09651	HNRNPA1	Q9BUB5	MKNK1	S95	R97T	97	Missense	proximal	2	no	8.867	8.981	EPSD	TCGA;ICGC;COSMIC	8.316	Up-regulation
CAMK_MAPKAPK_MNK_MKNK1_ST	P09651	HNRNPA1	Q9BUB5	MKNK1	S142	R140Q	140	Missense	proximal	-2	no	8.361	7.742	EPSD	TCGA;ICGC;COSMIC	8.316	Loss
CAMK_MAPKAPK_MNK_MKNK1_ST	P09651	HNRNPA1	Q9BUB5	MKNK1	S142	R146M	146	Missense	distal	4	no	8.361	5.531	EPSD	TCGA;ICGC;COSMIC	8.316	Loss
CAMK_MAPKAPK_MNK_MKNK1_ST	P09651	HNRNPA1	Q9BUB5	MKNK1	S190	E185D	185	Missense	distal	-5	no	9.206	9.191	EPSD	TCGA;ICGC;COSMIC	8.316	Down-regulation
CAMK_MAPKAPK_MNK_MKNK1_ST	P09651	HNRNPA1	Q9BUB5	MKNK1	S190	E185K	185	Missense	distal	-5	no	9.206	9.128	EPSD	TCGA;ICGC;COSMIC	8.316	Down-regulation
CAMK_MAPKAPK_MNK_MKNK1_ST	P09651	HNRNPA1	Q9BUB5	MKNK1	S190	R194T	194	Missense	distal	4	no	9.206	6.501	EPSD	TCGA;ICGC;COSMIC	8.316	Loss
CAMK_MAPKAPK_MNK_MKNK1_ST	P09651	HNRNPA1	Q9BUB5	MKNK1	S192	E185D	185	Missense	distal	-7	no	14.039	14.026	PhosphoSitePlus;EPSD	TCGA;ICGC;COSMIC	8.316	Down-regulation
CAMK_MAPKAPK_MNK_MKNK1_ST	P09651	HNRNPA1	Q9BUB5	MKNK1	S192	E185K	185	Missense	distal	-7	no	14.039	13.999	PhosphoSitePlus;EPSD	TCGA;ICGC;COSMIC	8.316	Down-regulation
CAMK_MAPKAPK_MNK_MKNK1_ST	P09651	HNRNPA1	Q9BUB5	MKNK1	S192	R194T	194	Missense	proximal	2	no	14.039	14.152	PhosphoSitePlus;EPSD	TCGA;ICGC;COSMIC	8.316	Up-regulation
CAMK_MAPKAPK_MNK_MKNK1_ST	P09651	HNRNPA1	Q9BUB5	MKNK1	S192	G198C	198	Missense	distal	6	no	14.039	12.884	PhosphoSitePlus;EPSD	TCGA;ICGC;COSMIC	8.316	Down-regulation
CAMK_MAPKAPK_MNK_MKNK1_ST	P09651	HNRNPA1	Q9BUB5	MKNK1	S264	R265T	265	Missense	proximal	1	no	8.768	8.614	EPSD	TCGA;ICGC;COSMIC	8.316	Down-regulation
CAMK_MAPKAPK_MNK_MKNK1_ST	P09651	HNRNPA1	Q9BUB5	MKNK1	S264	S261C	261	Missense	distal	-3	no	8.768	6.473	EPSD	TCGA;ICGC;COSMIC	8.316	Loss
CAMK_MAPKAPK_MNK_MKNK1_ST	P09651	HNRNPA1	Q9BUB5	MKNK1	S338	R336T	336	Missense	proximal	-2	no	9.296	8.003	EPSD	TCGA	8.316	Loss
CAMK_MAPKAPK_MNK_MKNK1_ST	P09651	HNRNPA1	Q9BUB5	MKNK1	S338	G331R	331	Missense	distal	-7	no	9.296	9.254	EPSD	TCGA;COSMIC	8.316	Down-regulation
CAMK_MAPKAPK_MNK_MKNK1_ST	P09651	HNRNPA1	Q9BUB5	MKNK1	S360	G359S	359	Missense	proximal	-1	no	8.422	8.512	EPSD	TCGA;COSMIC	8.316	Up-regulation
CAMK_MAPKAPK_MNK_MKNK1_ST	P09651	HNRNPA1	Q9BUB5	MKNK1	S360	S365T	365	Missense	distal	5	no	8.422	8.089	EPSD	TCGA;COSMIC	8.316	Loss
CAMK_MAPKAPK_MNK_MKNK1_ST	P09651	HNRNPA1	Q9BUB5	MKNK1	S361	G359S	359	Missense	proximal	-2	no	8.788	9.492	EPSD	TCGA;COSMIC	8.316	Up-regulation
CAMK_MAPKAPK_MNK_MKNK1_ST	P09651	HNRNPA1	Q9BUB5	MKNK1	S361	S365T	365	Missense	distal	4	no	8.788	5.541	EPSD	TCGA;COSMIC	8.316	Loss
CAMK_MAPKAPK_MNK_MKNK1_ST	P09651	HNRNPA1	Q9BUB5	MKNK1	S362	G359S	359	Missense	distal	-3	no	12.714	13.589	EPSD;PhosphoSitePlus	TCGA;COSMIC	8.316	Up-regulation
CAMK_MAPKAPK_MNK_MKNK1_ST	P09651	HNRNPA1	Q9BUB5	MKNK1	S362	S365T	365	Missense	distal	3	no	12.714	12.826	EPSD;PhosphoSitePlus	TCGA;COSMIC	8.316	Up-regulation
CAMK_MAPKAPK_MNK_MKNK1_ST	P09651	HNRNPA1	Q9BUB5	MKNK1	S363	G359S	359	Missense	distal	-4	no	13.419	13.508	EPSD;PhosphoSitePlus	TCGA;COSMIC	8.316	Up-regulation
CAMK_MAPKAPK_MNK_MKNK1_ST	P09651	HNRNPA1	Q9BUB5	MKNK1	S363	S365T	365	Missense	proximal	2	no	13.419	13.659	EPSD;PhosphoSitePlus	TCGA;COSMIC	8.316	Up-regulation
CAMK_MAPKAPK_MNK_MKNK1_ST	P09651	HNRNPA1	Q9BUB5	MKNK1	S364	G359S	359	Missense	distal	-5	no	13.547	13.465	EPSD;PhosphoSitePlus	TCGA;COSMIC	8.316	Down-regulation
CAMK_MAPKAPK_MNK_MKNK1_ST	P09651	HNRNPA1	Q9BUB5	MKNK1	S364	R371T	371	Missense	distal	7	no	13.547	13.548	EPSD;PhosphoSitePlus	TCGA;COSMIC	8.316	Up-regulation
CAMK_MAPKAPK_MNK_MKNK1_ST	P09651	HNRNPA1	Q9BUB5	MKNK1	S364	S365T	365	Missense	proximal	1	no	13.547	13.327	EPSD;PhosphoSitePlus	TCGA;COSMIC	8.316	Down-regulation
CAMK_MAPKAPK_MNK_MKNK1_ST	P09651	HNRNPA1	Q9BUB5	MKNK1	S365	G359S	359	Missense	distal	-6	no	8.455	8.459	EPSD	TCGA;COSMIC	8.316	Up-regulation
CAMK_MAPKAPK_MNK_MKNK1_ST	P09651	HNRNPA1	Q9BUB5	MKNK1	S365	R371T	371	Missense	distal	6	no	8.455	8.027	EPSD	TCGA;COSMIC	8.316	Loss
CAMK_MAPKAPK_MNK_MKNK1_ST	O43597	SPRY2	Q9BUB5	MKNK1	S97	L94R	94	Missense	distal	-3	no	7.795	9.722	EPSD	TCGA;ICGC;COSMIC	8.316	Gain
CAMK_MAPKAPK_MNK_MKNK1_ST	O43597	SPRY2	Q9BUB5	MKNK1	S112	A105V	105	Missense	distal	-7	no	14.586	14.545	PhosphoSitePlus;EPSD	TCGA;ICGC;COSMIC	8.316	Down-regulation
CAMK_MAPKAPK_MNK_MKNK1_ST	O43597	SPRY2	Q9BUB5	MKNK1	S112	R119L	119	Missense	distal	7	no	14.586	14.662	PhosphoSitePlus;EPSD	TCGA;ICGC;COSMIC	8.316	Up-regulation
CAMK_MAPKAPK_MNK_MKNK1_ST	O43597	SPRY2	Q9BUB5	MKNK1	S115	R119L	119	Missense	distal	4	no	8.815	6.058	EPSD	TCGA;ICGC;COSMIC	8.316	Loss
CAMK_MAPKAPK_MNK_MKNK1_ST	O43597	SPRY2	Q9BUB5	MKNK1	S116	R119L	119	Missense	distal	3	no	8.371	8.430	EPSD	TCGA;ICGC;COSMIC	8.316	Up-regulation
CAMK_MAPKAPK_MNK_MKNK1_ST	O43597	SPRY2	Q9BUB5	MKNK1	S121	S127G	127	Missense	distal	6	no	13.724	13.642	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	8.316	Down-regulation
CAMK_MAPKAPK_MNK_MKNK1_ST	O43597	SPRY2	Q9BUB5	MKNK1	S121	R119L	119	Missense	proximal	-2	no	13.724	12.615	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	8.316	Down-regulation
CAMK_MAPKAPK_MNK_MKNK1_ST	O43597	SPRY2	Q9BUB5	MKNK1	T124	S127G	127	Missense	distal	3	no	9.610	9.638	EPSD	TCGA;ICGC;COSMIC	8.316	Up-regulation
CAMK_MAPKAPK_MNK_MKNK1_ST	O43597	SPRY2	Q9BUB5	MKNK1	T124	R119L	119	Missense	distal	-5	no	9.610	9.732	EPSD	TCGA;ICGC;COSMIC	8.316	Up-regulation
CAMK_MAPKAPK_MNK_MKNK1_ST	O43597	SPRY2	Q9BUB5	MKNK1	S138	G137R	137	Missense	proximal	-1	no	8.561	8.678	EPSD	TCGA;ICGC;COSMIC	8.316	Up-regulation
CAMK_MAPKAPK_MNK_MKNK1_ST	O43597	SPRY2	Q9BUB5	MKNK1	S138	P144S	144	Missense	distal	6	no	8.561	9.900	EPSD	TCGA;ICGC;COSMIC	8.316	Up-regulation
CAMK_MAPKAPK_MNK_MKNK1_ST	O43597	SPRY2	Q9BUB5	MKNK1	S138	L135M	135	Missense	distal	-3	no	8.561	8.179	EPSD	TCGA;ICGC	8.316	Loss
CAMK_MAPKAPK_MNK_MKNK1_ST	O43597	SPRY2	Q9BUB5	MKNK1	S138	S142F	142	Missense	distal	4	no	8.561	5.018	EPSD	TCGA;ICGC;COSMIC	8.316	Loss
Other_Aur_AurB_ST	P38159	RBMX	Q96GD4	AURKB	S88	P87L	87	Missense	proximal	-1	no	0.014	0.015	EPSD	TCGA;ICGC;COSMIC	0.010	Up-regulation
Other_Aur_AurB_ST	P38159	RBMX	Q96GD4	AURKB	S165	R164T	164	Missense	proximal	-1	no	0.020	0.013	EPSD	TCGA;COSMIC	0.010	Down-regulation
Other_Aur_AurB_ST	P38159	RBMX	Q96GD4	AURKB	S174	R172H	172	Missense	proximal	-2	no	0.073	0.003	EPSD	TCGA;ICGC;COSMIC	0.010	Loss
Other_Aur_AurB_ST	P38159	RBMX	Q96GD4	AURKB	S219	K217E	217	Missense	proximal	-2	no	0.013	-0.001	EPSD	TCGA	0.010	Loss
Other_Aur_AurB_ST	P38159	RBMX	Q96GD4	AURKB	T231	R229C	229	Missense	proximal	-2	no	0.065	-0.006	EPSD	TCGA	0.010	Loss
Other_Aur_AurB_ST	P38159	RBMX	Q96GD4	AURKB	S250	H248R	248	Missense	proximal	-2	no	0.001	0.072	EPSD	TCGA;ICGC;COSMIC	0.010	Gain
Other_Aur_AurB_ST	P38159	RBMX	Q96GD4	AURKB	S261	G259R	259	Missense	proximal	-2	no	0.002	0.074	EPSD	TCGA;COSMIC	0.010	Gain
Other_Aur_AurB_ST	P38159	RBMX	Q96GD4	AURKB	S284	R282T	282	Missense	proximal	-2	no	0.067	0.000	EPSD	TCGA;COSMIC	0.010	Loss
Other_Aur_AurB_ST	P38159	RBMX	Q96GD4	AURKB	S326	R331Q	331	Missense	distal	5	no	0.074	0.076	PhosphoSitePlus	TCGA;ICGC;COSMIC	0.010	Up-regulation
Other_Aur_AurB_ST	P38159	RBMX	Q96GD4	AURKB	S332	R331Q	331	Missense	proximal	-1	no	0.010	0.003	EPSD	TCGA;ICGC;COSMIC	0.010	Loss
Other_Aur_AurB_ST	P38159	RBMX	Q96GD4	AURKB	S363	R361C	361	Missense	proximal	-2	no	0.067	-0.003	EPSD	TCGA;ICGC;COSMIC	0.010	Loss
Other_Aur_AurB_ST	Q9NQS7	INCENP	Q96GD4	AURKB	S72	R69K	69	Missense	distal	-3	no	0.081	0.075	EPSD;PhosphoSitePlus	TCGA	0.010	Down-regulation
Other_Aur_AurB_ST	Q9NQS7	INCENP	Q96GD4	AURKB	S91	R88H	88	Missense	distal	-3	no	0.078	0.071	EPSD	TCGA;ICGC	0.010	Down-regulation
Other_Aur_AurB_ST	Q9NQS7	INCENP	Q96GD4	AURKB	S93	R88H	88	Missense	distal	-5	no	0.010	0.008	EPSD	TCGA;ICGC	0.010	Loss
Other_Aur_AurB_ST	Q9NQS7	INCENP	Q96GD4	AURKB	S94	R88H	88	Missense	distal	-6	no	0.070	0.069	EPSD	TCGA;ICGC	0.010	Down-regulation
Other_Aur_AurB_ST	Q9NQS7	INCENP	Q96GD4	AURKB	S103	R100S	100	Missense	distal	-3	no	0.012	0.006	EPSD	TCGA;ICGC;COSMIC	0.010	Loss
Other_Aur_AurB_ST	Q9NQS7	INCENP	Q96GD4	AURKB	S103	S103I	103	Missense	central	0	yes	0.012	0.000	EPSD	TCGA;ICGC;COSMIC	0.010	Loss
Other_Aur_AurB_ST	Q9NQS7	INCENP	Q96GD4	AURKB	S106	R100S	100	Missense	distal	-6	no	0.012	0.010	EPSD	TCGA;ICGC;COSMIC	0.010	Down-regulation
Other_Aur_AurB_ST	Q9NQS7	INCENP	Q96GD4	AURKB	S323	K321T	321	Missense	proximal	-2	no	0.016	0.007	EPSD	TCGA;ICGC;COSMIC	0.010	Loss
Other_Aur_AurB_ST	Q9NQS7	INCENP	Q96GD4	AURKB	S336	K342N	342	Missense	distal	6	no	0.078	0.077	EPSD	TCGA;ICGC;COSMIC	0.010	Down-regulation
Other_Aur_AurB_ST	Q9NQS7	INCENP	Q96GD4	AURKB	T343	K342N	342	Missense	proximal	-1	no	0.013	0.012	EPSD	TCGA;ICGC;COSMIC	0.010	Down-regulation
Other_Aur_AurB_ST	Q9NQS7	INCENP	Q96GD4	AURKB	T524	R522C	522	Missense	proximal	-2	no	0.072	0.002	EPSD	TCGA;ICGC;COSMIC	0.010	Loss
Other_Aur_AurB_ST	Q9NQS7	INCENP	Q96GD4	AURKB	T524	R522H	522	Missense	proximal	-2	no	0.072	0.002	EPSD	TCGA;ICGC	0.010	Loss
Other_Aur_AurB_ST	Q9NQS7	INCENP	Q96GD4	AURKB	T524	R527H	527	Missense	distal	3	no	0.072	0.073	EPSD	TCGA;ICGC;CCLE	0.010	Up-regulation
Other_Aur_AurB_ST	Q9NQS7	INCENP	Q96GD4	AURKB	S894	S894F	894	Missense	central	0	yes	0.011	0.000	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	0.010	Loss
Other_Aur_AurB_ST	Q14980	NUMA1	Q96GD4	AURKB	S76	H74R	74	Missense	proximal	-2	no	0.005	0.076	EPSD	TCGA;ICGC;COSMIC	0.010	Gain
Other_Aur_AurB_ST	Q14980	NUMA1	Q96GD4	AURKB	T99	L103F	103	Missense	distal	4	no	0.012	0.013	EPSD	TCGA;ICGC;COSMIC	0.010	Up-regulation
Other_Aur_AurB_ST	Q14980	NUMA1	Q96GD4	AURKB	S633	R631W	631	Missense	proximal	-2	no	0.073	0.004	EPSD	TCGA;ICGC;COSMIC	0.010	Loss
Other_Aur_AurB_ST	Q14980	NUMA1	Q96GD4	AURKB	S710	S710P	710	Missense	central	0	yes	0.011	0.000	EPSD	TCGA;ICGC	0.010	Loss
Other_Aur_AurB_ST	Q14980	NUMA1	Q96GD4	AURKB	S1145	Q1142R	1142	Missense	distal	-3	no	0.005	0.011	EPSD	TCGA;ICGC;COSMIC	0.010	Gain
Other_Aur_AurB_ST	Q14980	NUMA1	Q96GD4	AURKB	S1162	R1160Q	1160	Missense	proximal	-2	no	0.072	-0.002	EPSD	TCGA;ICGC;COSMIC	0.010	Loss
Other_Aur_AurB_ST	Q14980	NUMA1	Q96GD4	AURKB	S1162	T1166P	1166	Missense	distal	4	no	0.072	0.071	EPSD	TCGA;ICGC;COSMIC	0.010	Down-regulation
Other_Aur_AurB_ST	Q14980	NUMA1	Q96GD4	AURKB	S1162	R1157W	1157	Missense	distal	-5	no	0.072	0.070	EPSD	TCGA;ICGC;COSMIC	0.010	Down-regulation
Other_Aur_AurB_ST	Q14980	NUMA1	Q96GD4	AURKB	S1162	A1158T	1158	Missense	distal	-4	no	0.072	0.071	EPSD	TCGA;ICGC;COSMIC	0.010	Down-regulation
Other_Aur_AurB_ST	Q14980	NUMA1	Q96GD4	AURKB	S1287	E1285K	1285	Missense	proximal	-2	no	0.010	0.023	EPSD	TCGA;ICGC;COSMIC	0.010	Up-regulation
Other_Aur_AurB_ST	Q14980	NUMA1	Q96GD4	AURKB	S1287	R1286C	1286	Missense	proximal	-1	no	0.010	0.002	EPSD	TCGA;ICGC;COSMIC	0.010	Loss
Other_Aur_AurB_ST	Q14980	NUMA1	Q96GD4	AURKB	S1288	E1285K	1285	Missense	distal	-3	no	0.070	0.072	EPSD	TCGA;ICGC;COSMIC	0.010	Up-regulation
Other_Aur_AurB_ST	Q14980	NUMA1	Q96GD4	AURKB	S1288	R1286C	1286	Missense	proximal	-2	no	0.070	0.000	EPSD	TCGA;ICGC;COSMIC	0.010	Loss
Other_Aur_AurB_ST	Q14980	NUMA1	Q96GD4	AURKB	S1432	R1427Q	1427	Missense	distal	-5	no	0.013	0.011	EPSD	TCGA;ICGC;COSMIC	0.010	Down-regulation
Other_Aur_AurB_ST	Q14980	NUMA1	Q96GD4	AURKB	S1806	R1810H	1810	Missense	distal	4	no	0.016	0.015	EPSD	TCGA;COSMIC;GDSC;CCLE	0.010	Down-regulation
Other_Aur_AurB_ST	Q14980	NUMA1	Q96GD4	AURKB	S1806	R1810C	1810	Missense	distal	4	no	0.016	0.015	EPSD	TCGA;COSMIC;CCLE	0.010	Down-regulation
Other_Aur_AurB_ST	Q14980	NUMA1	Q96GD4	AURKB	T1811	R1810H	1810	Missense	proximal	-1	no	0.082	0.075	EPSD;PhosphoSitePlus	TCGA;COSMIC;GDSC;CCLE	0.010	Down-regulation
Other_Aur_AurB_ST	Q14980	NUMA1	Q96GD4	AURKB	T1811	R1810C	1810	Missense	proximal	-1	no	0.082	0.075	EPSD;PhosphoSitePlus	TCGA;COSMIC;CCLE	0.010	Down-regulation
Other_Aur_AurB_ST	Q14980	NUMA1	Q96GD4	AURKB	T1812	R1810H	1810	Missense	proximal	-2	no	0.073	0.002	EPSD	TCGA;COSMIC;GDSC;CCLE	0.010	Loss
Other_Aur_AurB_ST	Q14980	NUMA1	Q96GD4	AURKB	T1812	R1810C	1810	Missense	proximal	-2	no	0.073	0.003	EPSD	TCGA;COSMIC;CCLE	0.010	Loss
Other_Aur_AurB_ST	Q14980	NUMA1	Q96GD4	AURKB	S1852	S1852Y	1852	Missense	central	0	yes	0.012	0.000	EPSD	TCGA;COSMIC	0.010	Loss
Other_Aur_AurB_ST	Q14980	NUMA1	Q96GD4	AURKB	S1882	R1881H	1881	Missense	proximal	-1	no	0.014	0.006	EPSD	TCGA;COSMIC	0.010	Loss
Other_Aur_AurB_ST	Q14980	NUMA1	Q96GD4	AURKB	S1882	S1882N	1882	Missense	central	0	yes	0.014	0.000	EPSD	TCGA	0.010	Loss
Other_Aur_AurB_ST	Q14980	NUMA1	Q96GD4	AURKB	S1883	G1890R	1890	Missense	distal	7	no	0.072	0.073	EPSD	TCGA;COSMIC	0.010	Up-regulation
Other_Aur_AurB_ST	Q14980	NUMA1	Q96GD4	AURKB	S1883	R1881H	1881	Missense	proximal	-2	no	0.072	0.002	EPSD	TCGA;COSMIC	0.010	Loss
Other_Aur_AurB_ST	Q14980	NUMA1	Q96GD4	AURKB	S1887	G1894R	1894	Missense	distal	7	no	0.080	0.081	EPSD	TCGA;COSMIC	0.010	Up-regulation
Other_Aur_AurB_ST	Q14980	NUMA1	Q96GD4	AURKB	S1887	S1887F	1887	Missense	central	0	yes	0.080	0.000	EPSD	TCGA	0.010	Loss
Other_Aur_AurB_ST	Q14980	NUMA1	Q96GD4	AURKB	S1887	R1885C	1885	Missense	proximal	-2	no	0.080	0.010	EPSD	TCGA;COSMIC	0.010	Down-regulation
Other_Aur_AurB_ST	Q14980	NUMA1	Q96GD4	AURKB	S1887	R1881H	1881	Missense	distal	-6	no	0.080	0.079	EPSD	TCGA;COSMIC	0.010	Down-regulation
Other_Aur_AurB_ST	Q14980	NUMA1	Q96GD4	AURKB	S1892	G1890R	1890	Missense	proximal	-2	no	-0.001	0.071	EPSD	TCGA;COSMIC	0.010	Gain
Other_Aur_AurB_ST	Q14980	NUMA1	Q96GD4	AURKB	S1901	G1905S	1905	Missense	distal	4	no	0.069	0.070	EPSD	TCGA;COSMIC	0.010	Up-regulation
Other_Aur_AurB_ST	Q14980	NUMA1	Q96GD4	AURKB	S1969	R1967Q	1967	Missense	proximal	-2	no	0.080	0.007	EPSD;PhosphoSitePlus	TCGA;COSMIC	0.010	Loss
Other_Aur_AurB_ST	Q14980	NUMA1	Q96GD4	AURKB	S1969	R1966H	1966	Missense	distal	-3	no	0.080	0.074	EPSD;PhosphoSitePlus	TCGA;COSMIC	0.010	Down-regulation
Other_Aur_AurB_ST	Q14980	NUMA1	Q96GD4	AURKB	S1991	R1987H	1987	Missense	distal	-4	no	0.069	0.068	EPSD	TCGA;COSMIC;GDSC;CCLE	0.010	Down-regulation
Other_Aur_AurB_ST	Q14980	NUMA1	Q96GD4	AURKB	T2007	R2012H	2012	Missense	distal	5	no	0.008	0.010	EPSD	TCGA;COSMIC	0.010	Gain
Other_Aur_AurB_ST	Q14980	NUMA1	Q96GD4	AURKB	S2026	R2019Q	2019	Missense	distal	-7	no	0.019	0.020	EPSD	TCGA	0.010	Up-regulation
Other_Aur_AurB_ST	Q14980	NUMA1	Q96GD4	AURKB	S2026	R2023H	2023	Missense	distal	-3	no	0.019	0.013	EPSD	TCGA	0.010	Down-regulation
Other_Aur_AurB_ST	Q14980	NUMA1	Q96GD4	AURKB	S2047	R2045C	2045	Missense	proximal	-2	no	0.077	0.007	EPSD;PhosphoSitePlus	TCGA;COSMIC	0.010	Loss
Other_Aur_AurB_ST	Q14980	NUMA1	Q96GD4	AURKB	S2047	R2045H	2045	Missense	proximal	-2	no	0.077	0.006	EPSD;PhosphoSitePlus	TCGA;COSMIC	0.010	Loss
Other_Aur_AurB_ST	Q14980	NUMA1	Q96GD4	AURKB	S2077	K2075Q	2075	Missense	proximal	-2	no	0.010	-0.005	EPSD	TCGA;COSMIC	0.010	Loss
Other_Aur_AurB_ST	Q14980	NUMA1	Q96GD4	AURKB	S2077	R2081C	2081	Missense	distal	4	no	0.010	0.009	EPSD	TCGA;COSMIC	0.010	Loss
Other_Aur_AurB_ST	Q14980	NUMA1	Q96GD4	AURKB	S2087	R2081C	2081	Missense	distal	-6	no	0.078	0.077	EPSD	TCGA;COSMIC	0.010	Down-regulation
Other_Aur_AurB_ST	Q96FF9	CDCA5	Q96GD4	AURKB	S15	Q13H	13	Missense	proximal	-2	no	0.007	0.010	EPSD	TCGA;ICGC;COSMIC	0.010	Gain
Other_Aur_AurB_ST	Q96FF9	CDCA5	Q96GD4	AURKB	S29	S33L	33	Missense	distal	4	no	0.077	0.076	EPSD	TCGA;ICGC;COSMIC	0.010	Down-regulation
Other_Aur_AurB_ST	Q96FF9	CDCA5	Q96GD4	AURKB	S29	S29F	29	Missense	central	0	yes	0.077	0.000	EPSD	TCGA;ICGC;COSMIC	0.010	Loss
Other_Aur_AurB_ST	Q96FF9	CDCA5	Q96GD4	AURKB	S33	S33L	33	Missense	central	0	yes	0.077	0.000	PhosphoSitePlus;EPSD	TCGA;ICGC;COSMIC	0.010	Loss
Other_Aur_AurB_ST	Q96FF9	CDCA5	Q96GD4	AURKB	S33	S29F	29	Missense	distal	-4	no	0.077	0.076	PhosphoSitePlus;EPSD	TCGA;ICGC;COSMIC	0.010	Down-regulation
Other_Aur_AurB_ST	Q96FF9	CDCA5	Q96GD4	AURKB	S145	R144C	144	Missense	proximal	-1	no	0.081	0.073	EPSD	TCGA;ICGC;COSMIC;GDSC;CCLE	0.010	Down-regulation
Other_Aur_AurB_ST	Q96FF9	CDCA5	Q96GD4	AURKB	S164	S158F	158	Missense	distal	-6	no	0.078	0.077	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	0.010	Down-regulation
Other_Aur_AurB_ST	Q9H0H5	RACGAP1	Q96GD4	AURKB	S185	R184C	184	Missense	proximal	-1	no	0.083	0.076	EPSD	TCGA;ICGC;COSMIC	0.010	Down-regulation
Other_Aur_AurB_ST	Q9H0H5	RACGAP1	Q96GD4	AURKB	T186	R184C	184	Missense	proximal	-2	no	0.078	0.008	EPSD	TCGA;ICGC;COSMIC	0.010	Loss
Other_Aur_AurB_ST	Q9H0H5	RACGAP1	Q96GD4	AURKB	S187	S185T	185	Missense	proximal	-2	no	0.009	0.015	EPSD	TCGA;ICGC;COSMIC	0.010	Gain
Other_Aur_AurB_ST	Q9H0H5	RACGAP1	Q96GD4	AURKB	S203	R202C	202	Missense	proximal	-1	no	0.013	0.006	EPSD	TCGA;ICGC;COSMIC	0.010	Loss
Other_Aur_AurB_ST	Q9H0H5	RACGAP1	Q96GD4	AURKB	T249	R247M	247	Missense	proximal	-2	no	0.081	0.010	EPSD;PhosphoSitePlus	TCGA;ICGC	0.010	Down-regulation
Other_Aur_AurB_ST	Q9H0H5	RACGAP1	Q96GD4	AURKB	S313	K311R	311	Missense	proximal	-2	no	0.017	0.076	EPSD	TCGA;ICGC;COSMIC	0.010	Up-regulation
Other_Aur_AurB_ST	Q9H0H5	RACGAP1	Q96GD4	AURKB	S600	R597K	597	Missense	distal	-3	no	0.010	0.004	EPSD	TCGA;ICGC	0.010	Loss
Other_Aur_AurB_ST	Q9H0H5	RACGAP1	Q96GD4	AURKB	T601	R597K	597	Missense	distal	-4	no	0.070	0.069	EPSD	TCGA;ICGC	0.010	Down-regulation
Other_Aur_AurB_ST	O14777	NDC80	Q96GD4	AURKB	S4	K2E	2	Missense	proximal	-2	no	0.020	0.006	EPSD	TCGA;ICGC;COSMIC	0.010	Loss
Other_Aur_AurB_ST	O14777	NDC80	Q96GD4	AURKB	S5	K2E	2	Missense	distal	-3	no	0.075	0.073	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	0.010	Down-regulation
Other_Aur_AurB_ST	O14777	NDC80	Q96GD4	AURKB	S15	R13H	13	Missense	proximal	-2	no	0.067	-0.003	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	0.010	Loss
Other_Aur_AurB_ST	O14777	NDC80	Q96GD4	AURKB	S44	E51K	51	Missense	distal	7	no	0.010	0.011	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	0.010	Up-regulation
Other_Aur_AurB_ST	O14777	NDC80	Q96GD4	AURKB	T49	R52G	52	Missense	distal	3	no	0.010	0.011	PhosphoSitePlus;EPSD	TCGA;ICGC;COSMIC	0.010	Up-regulation
Other_Aur_AurB_ST	O14777	NDC80	Q96GD4	AURKB	S55	R52G	52	Missense	distal	-3	no	0.017	0.010	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	0.010	Down-regulation
Other_Aur_AurB_ST	O14777	NDC80	Q96GD4	AURKB	S62	S62N	62	Missense	central	0	yes	0.071	0.000	EPSD	TCGA;ICGC;COSMIC	0.010	Loss
Other_Aur_AurB_ST	O14777	NDC80	Q96GD4	AURKB	S62	R67W	67	Missense	distal	5	no	0.071	0.073	EPSD	TCGA;ICGC;COSMIC	0.010	Up-regulation
Other_Aur_AurB_ST	O14777	NDC80	Q96GD4	AURKB	S69	R67W	67	Missense	proximal	-2	no	0.072	0.002	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	0.010	Loss
Other_Aur_AurB_ST	O14777	NDC80	Q96GD4	AURKB	S201	E200K	200	Missense	proximal	-1	no	0.013	0.014	EPSD	TCGA;ICGC;COSMIC	0.010	Up-regulation
Other_Aur_AurB_ST	O14777	NDC80	Q96GD4	AURKB	S202	E200K	200	Missense	proximal	-2	no	0.001	0.014	EPSD	TCGA;ICGC;COSMIC	0.010	Gain
Other_Aur_AurB_ST	P98179	RBM3	Q96GD4	AURKB	T43	V38G	38	Missense	distal	-5	no	0.070	0.071	EPSD	TCGA;ICGC;COSMIC	0.010	Up-regulation
Other_Aur_AurB_ST	P98179	RBM3	Q96GD4	AURKB	S102	R99C	99	Missense	distal	-3	no	0.012	0.006	EPSD	TCGA;ICGC;COSMIC;GDSC;CCLE	0.010	Loss
Other_Aur_AurB_ST	P98179	RBM3	Q96GD4	AURKB	S147	R145H	145	Missense	proximal	-2	no	0.070	-0.001	PhosphoSitePlus	TCGA	0.010	Loss
Other_Aur_AurB_ST	Q8NEM2	SHCBP1	Q96GD4	AURKB	S434	K437T	437	Missense	distal	3	no	0.012	0.013	EPSD	TCGA;ICGC;COSMIC	0.010	Up-regulation
Other_Aur_AurB_ST	Q8NEM2	SHCBP1	Q96GD4	AURKB	S474	R472Q	472	Missense	proximal	-2	no	0.071	-0.003	EPSD	TCGA;ICGC;COSMIC	0.010	Loss
Other_Aur_AurB_ST	Q8NEM2	SHCBP1	Q96GD4	AURKB	S474	T473P	473	Missense	proximal	-1	no	0.071	0.070	EPSD	TCGA;ICGC;COSMIC	0.010	Down-regulation
Other_Aur_AurB_ST	P06400	RB1	Q96GD4	AURKB	S260	R255Q	255	Missense	distal	-5	no	0.010	0.008	EPSD	TCGA;ICGC;COSMIC	0.010	Loss
Other_Aur_AurB_ST	P06400	RB1	Q96GD4	AURKB	S260	R259S	259	Missense	proximal	-1	no	0.010	0.002	EPSD	TCGA;ICGC;COSMIC	0.010	Loss
Other_Aur_AurB_ST	P06400	RB1	Q96GD4	AURKB	S862	K860R	860	Missense	proximal	-2	no	0.019	0.078	EPSD	TCGA;ICGC;COSMIC	0.010	Up-regulation
Other_Aur_AurB_ST	P06400	RB1	Q96GD4	AURKB	S862	R857C	857	Missense	distal	-5	no	0.019	0.017	EPSD	TCGA;ICGC;COSMIC	0.010	Down-regulation
Other_Aur_AurB_ST	P78527	PRKDC	Q96GD4	AURKB	S56	Q54R	54	Missense	proximal	-2	no	-0.009	0.064	EPSD	TCGA;ICGC	0.010	Gain
Other_Aur_AurB_ST	P78527	PRKDC	Q96GD4	AURKB	S1065	L1063R	1063	Missense	proximal	-2	no	0.007	0.077	EPSD	TCGA;ICGC;COSMIC	0.010	Gain
Other_Aur_AurB_ST	P78527	PRKDC	Q96GD4	AURKB	S1187	K1186R	1186	Missense	proximal	-1	no	0.011	0.017	EPSD	TCGA;ICGC;COSMIC	0.010	Up-regulation
Other_Aur_AurB_ST	P78527	PRKDC	Q96GD4	AURKB	S1187	R1184Q	1184	Missense	distal	-3	no	0.011	0.004	EPSD	TCGA;ICGC	0.010	Loss
Other_Aur_AurB_ST	Q12888	TP53BP1	Q96GD4	AURKB	T548	E546K	546	Missense	proximal	-2	no	-0.004	0.010	EPSD	TCGA	0.010	Gain
Other_Aur_AurB_ST	Q12888	TP53BP1	Q96GD4	AURKB	S635	S640F	640	Missense	distal	5	no	0.011	0.012	EPSD	TCGA;COSMIC	0.010	Up-regulation
Other_Aur_AurB_ST	Q12888	TP53BP1	Q96GD4	AURKB	T1270	E1271K	1271	Missense	proximal	1	no	0.016	0.015	EPSD	TCGA;COSMIC	0.010	Down-regulation
Other_Aur_AurB_ST	Q12888	TP53BP1	Q96GD4	AURKB	T1273	E1271K	1271	Missense	proximal	-2	no	-0.002	0.011	EPSD	TCGA;COSMIC	0.010	Gain
Other_Aur_AurB_ST	Q12888	TP53BP1	Q96GD4	AURKB	S1310	S1311F	1311	Missense	proximal	1	no	0.013	0.014	EPSD	TCGA;COSMIC	0.010	Up-regulation
Other_Aur_AurB_ST	Q12888	TP53BP1	Q96GD4	AURKB	S1686	R1682W	1682	Missense	distal	-4	no	0.074	0.073	EPSD	TCGA;COSMIC	0.010	Down-regulation
Other_Aur_AurB_ST	Q12888	TP53BP1	Q96GD4	AURKB	S1686	R1682Q	1682	Missense	distal	-4	no	0.074	0.073	EPSD	TCGA;COSMIC	0.010	Down-regulation
Other_Aur_AurB_ST	Q53HL2	CDCA8	Q96GD4	AURKB	T100	E95K	95	Missense	distal	-5	no	0.009	0.010	EPSD	TCGA;ICGC	0.010	Gain
Other_Aur_AurB_ST	Q9NQG5	RPRD1B	Q96GD4	AURKB	S128	S128P	128	Missense	central	0	yes	0.012	0.000	EPSD	TCGA;ICGC;COSMIC	0.010	Loss
Other_Aur_AurB_ST	Q9NQG5	RPRD1B	Q96GD4	AURKB	S145	K143N	143	Missense	proximal	-2	no	0.012	0.000	PhosphoSitePlus	TCGA;ICGC;COSMIC	0.010	Loss
Other_Aur_AurB_ST	Q96K21	ZFYVE19	Q96GD4	AURKB	T345	V344A	344	Missense	proximal	-1	no	0.064	0.065	EPSD	TCGA;COSMIC	0.010	Up-regulation
Other_Aur_AurB_ST	O00571	DDX3X	Q96GD4	AURKB	S82	G80R	80	Missense	proximal	-2	no	0.010	0.082	EPSD	TCGA;COSMIC	0.010	Up-regulation
Other_Aur_AurB_ST	O00571	DDX3X	Q96GD4	AURKB	S83	G80R	80	Missense	distal	-3	no	0.012	0.018	EPSD	TCGA;COSMIC	0.010	Up-regulation
Other_Aur_AurB_ST	O00571	DDX3X	Q96GD4	AURKB	S102	R99H	99	Missense	distal	-3	no	0.011	0.005	EPSD	TCGA;COSMIC	0.010	Loss
Other_Aur_AurB_ST	O00571	DDX3X	Q96GD4	AURKB	S102	R99C	99	Missense	distal	-3	no	0.011	0.005	EPSD	TCGA;COSMIC	0.010	Loss
Other_Aur_AurB_ST	O00571	DDX3X	Q96GD4	AURKB	S102	R101W	101	Missense	proximal	-1	no	0.011	0.004	EPSD	TCGA;COSMIC	0.010	Loss
Other_Aur_AurB_ST	O00571	DDX3X	Q96GD4	AURKB	T201	R199C	199	Missense	proximal	-2	no	0.070	-0.001	EPSD	TCGA;COSMIC	0.010	Loss
Other_Aur_AurB_ST	O00571	DDX3X	Q96GD4	AURKB	T201	R199P	199	Missense	proximal	-2	no	0.070	-0.005	EPSD	TCGA;COSMIC;CCLE	0.010	Loss
Other_Aur_AurB_ST	O00571	DDX3X	Q96GD4	AURKB	T204	R199C	199	Missense	distal	-5	no	0.070	0.068	EPSD	TCGA;COSMIC	0.010	Down-regulation
Other_Aur_AurB_ST	O00571	DDX3X	Q96GD4	AURKB	T204	K208N	208	Missense	distal	4	no	0.070	0.069	EPSD	TCGA;COSMIC;CCLE	0.010	Down-regulation
Other_Aur_AurB_ST	O00571	DDX3X	Q96GD4	AURKB	T204	R199P	199	Missense	distal	-5	no	0.070	0.068	EPSD	TCGA;COSMIC;CCLE	0.010	Down-regulation
Other_Aur_AurB_ST	O00571	DDX3X	Q96GD4	AURKB	S290	S290L	290	Missense	central	0	yes	0.017	0.000	EPSD	TCGA;ICGC;COSMIC	0.010	Loss
Other_Aur_AurB_ST	O00571	DDX3X	Q96GD4	AURKB	S429	K427T	427	Missense	proximal	-2	no	0.020	0.012	EPSD	TCGA;ICGC;COSMIC	0.010	Down-regulation
Other_Aur_AurB_ST	O00571	DDX3X	Q96GD4	AURKB	S583	R587C	587	Missense	distal	4	no	0.011	0.010	EPSD	TCGA;ICGC;COSMIC	0.010	Down-regulation
Other_Aur_AurB_ST	O00571	DDX3X	Q96GD4	AURKB	S588	R587C	587	Missense	proximal	-1	no	0.018	0.010	EPSD	TCGA;ICGC;COSMIC	0.010	Down-regulation
Other_Aur_AurB_ST	O00571	DDX3X	Q96GD4	AURKB	S588	R585C	585	Missense	distal	-3	no	0.018	0.011	EPSD	TCGA;ICGC	0.010	Down-regulation
Other_Aur_AurB_ST	O00571	DDX3X	Q96GD4	AURKB	S591	R587C	587	Missense	distal	-4	no	0.010	0.009	EPSD	TCGA;ICGC;COSMIC	0.010	Loss
Other_Aur_AurB_ST	O00571	DDX3X	Q96GD4	AURKB	S591	R585C	585	Missense	distal	-6	no	0.010	0.009	EPSD	TCGA;ICGC	0.010	Loss
Other_Aur_AurB_ST	O00571	DDX3X	Q96GD4	AURKB	S605	R603Q	603	Missense	proximal	-2	no	0.070	-0.004	EPSD	TCGA;ICGC;COSMIC;CCLE	0.010	Loss
Other_Aur_AurB_ST	Q99661	KIF2C	Q96GD4	AURKB	S95	R93Q	93	Missense	proximal	-2	no	0.084	0.010	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	0.010	Down-regulation
Other_Aur_AurB_ST	Q99661	KIF2C	Q96GD4	AURKB	S109	R113C	113	Missense	distal	4	no	0.011	0.010	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	0.010	Down-regulation
Other_Aur_AurB_ST	Q99661	KIF2C	Q96GD4	AURKB	S109	R108Q	108	Missense	proximal	-1	no	0.011	0.003	EPSD;PhosphoSitePlus	TCGA;ICGC	0.010	Loss
Other_Aur_AurB_ST	Q99661	KIF2C	Q96GD4	AURKB	S111	R108Q	108	Missense	distal	-3	no	0.013	0.006	EPSD;PhosphoSitePlus	TCGA;ICGC	0.010	Loss
Other_Aur_AurB_ST	Q99661	KIF2C	Q96GD4	AURKB	T112	R113C	113	Missense	proximal	1	no	0.067	0.068	EPSD	TCGA;ICGC;COSMIC	0.010	Up-regulation
Other_Aur_AurB_ST	Q99661	KIF2C	Q96GD4	AURKB	T112	R108Q	108	Missense	distal	-4	no	0.067	0.066	EPSD	TCGA;ICGC	0.010	Down-regulation
Other_Aur_AurB_ST	Q99661	KIF2C	Q96GD4	AURKB	S115	R113C	113	Missense	proximal	-2	no	0.071	0.000	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	0.010	Loss
Other_Aur_AurB_ST	Q99661	KIF2C	Q96GD4	AURKB	S115	R121H	121	Missense	distal	6	no	0.071	0.070	EPSD;PhosphoSitePlus	TCGA;ICGC;CCLE	0.010	Down-regulation
Other_Aur_AurB_ST	Q99661	KIF2C	Q96GD4	AURKB	S115	R121C	121	Missense	distal	6	no	0.071	0.070	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC;CCLE	0.010	Down-regulation
Other_Aur_AurB_ST	Q99661	KIF2C	Q96GD4	AURKB	S192	S187P	187	Missense	distal	-5	no	0.078	0.077	PhosphoSitePlus;EPSD	TCGA;COSMIC	0.010	Down-regulation
Other_Aur_AurB_ST	Q99661	KIF2C	Q96GD4	AURKB	S192	S187L	187	Missense	distal	-5	no	0.078	0.077	PhosphoSitePlus;EPSD	TCGA;COSMIC	0.010	Down-regulation
Other_Aur_AurB_ST	Q99661	KIF2C	Q96GD4	AURKB	S458	S453N	453	Missense	distal	-5	no	0.072	0.071	EPSD	TCGA;COSMIC	0.010	Down-regulation
Other_Aur_AurB_ST	Q99661	KIF2C	Q96GD4	AURKB	S715	Q713R	713	Missense	proximal	-2	no	-0.006	0.068	EPSD	TCGA;COSMIC	0.010	Gain
Other_Aur_AurB_ST	P14136	GFAP	Q96GD4	AURKB	T7	R5H	5	Missense	proximal	-2	no	0.076	0.006	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	0.010	Loss
Other_Aur_AurB_ST	P14136	GFAP	Q96GD4	AURKB	S38	R41L	41	Missense	distal	3	no	0.070	0.071	PhosphoSitePlus;EPSD	TCGA;ICGC;COSMIC	0.010	Up-regulation
Other_Aur_AurB_ST	P14136	GFAP	Q96GD4	AURKB	S38	R36C	36	Missense	proximal	-2	no	0.070	0.000	PhosphoSitePlus;EPSD	TCGA;ICGC;COSMIC	0.010	Loss
Other_Aur_AurB_ST	P14136	GFAP	Q96GD4	AURKB	S38	S38F	38	Missense	central	0	yes	0.070	0.000	PhosphoSitePlus;EPSD	TCGA;ICGC;COSMIC	0.010	Loss
Other_Aur_AurB_ST	Q3KR16	PLEKHG6	Q96GD4	AURKB	S543	E548K	548	Missense	distal	5	no	0.069	0.068	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	0.010	Down-regulation
Other_Aur_AurB_ST	Q3KR16	PLEKHG6	Q96GD4	AURKB	S550	E548K	548	Missense	proximal	-2	no	-0.002	0.012	EPSD	TCGA;ICGC;COSMIC	0.010	Gain
Other_Aur_AurB_ST	Q3KR16	PLEKHG6	Q96GD4	AURKB	S603	G600R	600	Missense	distal	-3	no	0.010	0.017	EPSD	TCGA;ICGC;COSMIC	0.010	Up-regulation
Other_Aur_AurB_ST	Q3KR16	PLEKHG6	Q96GD4	AURKB	S603	R607H	607	Missense	distal	4	no	0.010	0.009	EPSD	TCGA;ICGC;COSMIC	0.010	Loss
Other_Aur_AurB_ST	Q3KR16	PLEKHG6	Q96GD4	AURKB	T620	R618H	618	Missense	proximal	-2	no	0.068	-0.003	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	0.010	Loss
Other_Aur_AurB_ST	Q3KR16	PLEKHG6	Q96GD4	AURKB	T620	R614W	614	Missense	distal	-6	no	0.068	0.066	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	0.010	Down-regulation
Other_Aur_AurB_ST	Q3KR16	PLEKHG6	Q96GD4	AURKB	S645	R643C	643	Missense	proximal	-2	no	0.078	0.007	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	0.010	Loss
Other_Aur_AurB_ST	Q3KR16	PLEKHG6	Q96GD4	AURKB	S712	E710K	710	Missense	proximal	-2	no	-0.001	0.013	EPSD	TCGA;ICGC;COSMIC	0.010	Gain
Other_Aur_AurB_ST	Q96GD4	AURKB	Q96GD4	AURKB	T232	R230S	230	Missense	proximal	-2	no	0.078	0.005	EPSD;PhosphoSitePlus	TCGA;COSMIC	0.010	Loss
Other_Aur_AurB_ST	P17661	DES	Q96GD4	AURKB	S12	R10H	10	Missense	proximal	-2	no	0.070	0.000	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	0.010	Loss
Other_Aur_AurB_ST	P17661	DES	Q96GD4	AURKB	S45	K43E	43	Missense	proximal	-2	no	0.010	-0.003	EPSD	TCGA;ICGC;COSMIC	0.010	Loss
Other_Aur_AurB_ST	P17661	DES	Q96GD4	AURKB	S414	E412K	412	Missense	proximal	-2	no	0.002	0.015	EPSD	TCGA;ICGC;COSMIC	0.010	Gain
Other_Aur_AurB_ST	P35659	DEK	Q96GD4	AURKB	S251	D248H	248	Missense	distal	-3	no	0.012	0.013	EPSD	TCGA;ICGC;COSMIC	0.010	Up-regulation
Other_Aur_AurB_ST	P35659	DEK	Q96GD4	AURKB	S251	K249T	249	Missense	proximal	-2	no	0.012	0.004	EPSD	TCGA;ICGC;COSMIC	0.010	Loss
Other_Aur_AurB_ST	P05787	KRT8	Q96GD4	AURKB	T187	E192K	192	Missense	distal	5	no	0.015	0.014	EPSD	TCGA;COSMIC	0.010	Down-regulation
Other_Aur_AurB_ST	P04637	TP53	Q96GD4	AURKB	S183	H179R	179	Missense	distal	-4	no	0.073	0.074	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC;GDSC;CCLE	0.010	Up-regulation
Other_Aur_AurB_ST	P04637	TP53	Q96GD4	AURKB	S183	R181H	181	Missense	proximal	-2	no	0.073	0.002	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC;CCLE	0.010	Loss
Other_Aur_AurB_ST	P04637	TP53	Q96GD4	AURKB	S183	H179Y	179	Missense	distal	-4	no	0.073	0.072	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	0.010	Down-regulation
Other_Aur_AurB_ST	P04637	TP53	Q96GD4	AURKB	S183	H178Q	178	Missense	distal	-5	no	0.073	0.072	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	0.010	Down-regulation
Other_Aur_AurB_ST	P04637	TP53	Q96GD4	AURKB	S183	E180K	180	Missense	distal	-3	no	0.073	0.074	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC;CCLE	0.010	Up-regulation
Other_Aur_AurB_ST	P04637	TP53	Q96GD4	AURKB	S183	H179N	179	Missense	distal	-4	no	0.073	0.072	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	0.010	Down-regulation
Other_Aur_AurB_ST	P04637	TP53	Q96GD4	AURKB	S183	H179P	179	Missense	distal	-4	no	0.073	0.072	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	0.010	Down-regulation
Other_Aur_AurB_ST	P04637	TP53	Q96GD4	AURKB	S183	H179L	179	Missense	distal	-4	no	0.073	0.072	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	0.010	Down-regulation
Other_Aur_AurB_ST	P04637	TP53	Q96GD4	AURKB	S183	H179D	179	Missense	distal	-4	no	0.073	0.072	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC;GDSC;CCLE	0.010	Down-regulation
Other_Aur_AurB_ST	P04637	TP53	Q96GD4	AURKB	S183	P177R	177	Missense	distal	-6	no	0.073	0.074	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	0.010	Up-regulation
Other_Aur_AurB_ST	P04637	TP53	Q96GD4	AURKB	S183	H179Q	179	Missense	distal	-4	no	0.073	0.072	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC;GDSC;CCLE	0.010	Down-regulation
Other_Aur_AurB_ST	P04637	TP53	Q96GD4	AURKB	S183	R181P	181	Missense	proximal	-2	no	0.073	-0.002	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC;CCLE	0.010	Loss
Other_Aur_AurB_ST	P04637	TP53	Q96GD4	AURKB	S183	C176R	176	Missense	distal	-7	no	0.073	0.072	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	0.010	Down-regulation
Other_Aur_AurB_ST	P04637	TP53	Q96GD4	AURKB	S183	R181C	181	Missense	proximal	-2	no	0.073	0.002	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC;GDSC;CCLE	0.010	Loss
Other_Aur_AurB_ST	P04637	TP53	Q96GD4	AURKB	T211	T211I	211	Missense	central	0	yes	0.069	0.000	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC;CCLE	0.010	Loss
Other_Aur_AurB_ST	P04637	TP53	Q96GD4	AURKB	T211	R209K	209	Missense	proximal	-2	no	0.069	0.010	EPSD;PhosphoSitePlus	TCGA;COSMIC	0.010	Down-regulation
Other_Aur_AurB_ST	P04637	TP53	Q96GD4	AURKB	T211	R209S	209	Missense	proximal	-2	no	0.069	-0.004	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	0.010	Loss
Other_Aur_AurB_ST	P04637	TP53	Q96GD4	AURKB	T211	S215R	215	Missense	distal	4	no	0.069	0.070	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC;GDSC;CCLE	0.010	Up-regulation
Other_Aur_AurB_ST	P04637	TP53	Q96GD4	AURKB	T211	R209I	209	Missense	proximal	-2	no	0.069	-0.003	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	0.010	Loss
Other_Aur_AurB_ST	P04637	TP53	Q96GD4	AURKB	T211	T211A	211	Missense	central	0	yes	0.069	0.000	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC;CCLE	0.010	Loss
Other_Aur_AurB_ST	P04637	TP53	Q96GD4	AURKB	S215	R213Q	213	Missense	proximal	-2	no	0.072	-0.002	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC;GDSC;CCLE	0.010	Loss
Other_Aur_AurB_ST	P04637	TP53	Q96GD4	AURKB	S215	H214R	214	Missense	proximal	-1	no	0.072	0.079	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC;GDSC;CCLE	0.010	Up-regulation
Other_Aur_AurB_ST	P04637	TP53	Q96GD4	AURKB	S215	V218E	218	Missense	distal	3	no	0.072	0.071	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	0.010	Down-regulation
Other_Aur_AurB_ST	P04637	TP53	Q96GD4	AURKB	S215	S215I	215	Missense	central	0	yes	0.072	0.000	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC;GDSC;CCLE	0.010	Loss
Other_Aur_AurB_ST	P04637	TP53	Q96GD4	AURKB	S215	Y220S	220	Missense	distal	5	no	0.072	0.071	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	0.010	Down-regulation
Other_Aur_AurB_ST	P04637	TP53	Q96GD4	AURKB	S215	S215N	215	Missense	central	0	yes	0.072	0.000	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC;GDSC;CCLE	0.010	Loss
Other_Aur_AurB_ST	P04637	TP53	Q96GD4	AURKB	S215	R213L	213	Missense	proximal	-2	no	0.072	0.001	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC;GDSC;CCLE	0.010	Loss
Other_Aur_AurB_ST	P04637	TP53	Q96GD4	AURKB	S215	R209K	209	Missense	distal	-6	no	0.072	0.070	EPSD;PhosphoSitePlus	TCGA;COSMIC	0.010	Down-regulation
Other_Aur_AurB_ST	P04637	TP53	Q96GD4	AURKB	S215	R213P	213	Missense	proximal	-2	no	0.072	-0.003	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	0.010	Loss
Other_Aur_AurB_ST	P04637	TP53	Q96GD4	AURKB	S215	H214L	214	Missense	proximal	-1	no	0.072	0.071	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	0.010	Down-regulation
Other_Aur_AurB_ST	P04637	TP53	Q96GD4	AURKB	S215	S215G	215	Missense	central	0	yes	0.072	0.000	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC;GDSC;CCLE	0.010	Loss
Other_Aur_AurB_ST	P04637	TP53	Q96GD4	AURKB	S215	R209S	209	Missense	distal	-6	no	0.072	0.070	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	0.010	Down-regulation
Other_Aur_AurB_ST	P04637	TP53	Q96GD4	AURKB	S215	R213G	213	Missense	proximal	-2	no	0.072	0.000	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	0.010	Loss
Other_Aur_AurB_ST	P04637	TP53	Q96GD4	AURKB	S215	S215R	215	Missense	central	0	yes	0.072	0.000	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC;GDSC;CCLE	0.010	Loss
Other_Aur_AurB_ST	P04637	TP53	Q96GD4	AURKB	S215	R209I	209	Missense	distal	-6	no	0.072	0.070	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	0.010	Down-regulation
Other_Aur_AurB_ST	P04637	TP53	Q96GD4	AURKB	S269	R273C	273	Missense	distal	4	no	0.071	0.070	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC;GDSC;CCLE	0.010	Down-regulation
Other_Aur_AurB_ST	P04637	TP53	Q96GD4	AURKB	S269	R273L	273	Missense	distal	4	no	0.071	0.069	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC;GDSC;CCLE	0.010	Down-regulation
Other_Aur_AurB_ST	P04637	TP53	Q96GD4	AURKB	S269	R273S	273	Missense	distal	4	no	0.071	0.070	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	0.010	Down-regulation
Other_Aur_AurB_ST	P04637	TP53	Q96GD4	AURKB	S269	R273P	273	Missense	distal	4	no	0.071	0.069	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	0.010	Down-regulation
Other_Aur_AurB_ST	P04637	TP53	Q96GD4	AURKB	S269	R273H	273	Missense	distal	4	no	0.071	0.070	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC;GDSC;CCLE	0.010	Down-regulation
Other_Aur_AurB_ST	P04637	TP53	Q96GD4	AURKB	S269	V274D	274	Missense	distal	5	no	0.071	0.070	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC;CCLE	0.010	Down-regulation
Other_Aur_AurB_ST	P04637	TP53	Q96GD4	AURKB	S269	G266V	266	Missense	distal	-3	no	0.071	0.070	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC;GDSC;CCLE	0.010	Down-regulation
Other_Aur_AurB_ST	P04637	TP53	Q96GD4	AURKB	S269	R267L	267	Missense	proximal	-2	no	0.071	0.000	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC;GDSC;CCLE	0.010	Loss
Other_Aur_AurB_ST	P04637	TP53	Q96GD4	AURKB	S269	R267W	267	Missense	proximal	-2	no	0.071	0.001	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC;GDSC;CCLE	0.010	Loss
Other_Aur_AurB_ST	P04637	TP53	Q96GD4	AURKB	S269	R267Q	267	Missense	proximal	-2	no	0.071	-0.003	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC;CCLE	0.010	Loss
Other_Aur_AurB_ST	P04637	TP53	Q96GD4	AURKB	S269	G266R	266	Missense	distal	-3	no	0.071	0.077	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC;GDSC;CCLE	0.010	Up-regulation
Other_Aur_AurB_ST	P04637	TP53	Q96GD4	AURKB	S269	R267P	267	Missense	proximal	-2	no	0.071	-0.004	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC;GDSC;CCLE	0.010	Loss
Other_Aur_AurB_ST	P04637	TP53	Q96GD4	AURKB	S269	L265R	265	Missense	distal	-4	no	0.071	0.072	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	0.010	Up-regulation
Other_Aur_AurB_ST	P04637	TP53	Q96GD4	AURKB	S269	R267G	267	Missense	proximal	-2	no	0.071	-0.001	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	0.010	Loss
Other_Aur_AurB_ST	P04637	TP53	Q96GD4	AURKB	S269	F270S	270	Missense	proximal	1	no	0.071	0.070	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	0.010	Down-regulation
Other_Aur_AurB_ST	P04637	TP53	Q96GD4	AURKB	S269	R273G	273	Missense	distal	4	no	0.071	0.070	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	0.010	Down-regulation
Other_Aur_AurB_ST	P04637	TP53	Q96GD4	AURKB	S269	V272A	272	Missense	distal	3	no	0.071	0.070	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	0.010	Down-regulation
Other_Aur_AurB_ST	P04637	TP53	Q96GD4	AURKB	T284	R280T	280	Missense	distal	-4	no	0.077	0.076	PhosphoSitePlus;EPSD	TCGA;ICGC;COSMIC;GDSC;CCLE	0.010	Down-regulation
Other_Aur_AurB_ST	P04637	TP53	Q96GD4	AURKB	T284	G279R	279	Missense	distal	-5	no	0.077	0.079	PhosphoSitePlus;EPSD	TCGA;ICGC;COSMIC	0.010	Up-regulation
Other_Aur_AurB_ST	P04637	TP53	Q96GD4	AURKB	T284	P278A	278	Missense	distal	-6	no	0.077	0.078	PhosphoSitePlus;EPSD	TCGA;ICGC;COSMIC;GDSC;CCLE	0.010	Up-regulation
Other_Aur_AurB_ST	P04637	TP53	Q96GD4	AURKB	T284	R282W	282	Missense	proximal	-2	no	0.077	0.008	PhosphoSitePlus;EPSD	TCGA;ICGC;COSMIC;GDSC	0.010	Loss
Other_Aur_AurB_ST	P04637	TP53	Q96GD4	AURKB	T284	R283P	283	Missense	proximal	-1	no	0.077	0.069	PhosphoSitePlus;EPSD	TCGA;ICGC;COSMIC;GDSC;CCLE	0.010	Down-regulation
Other_Aur_AurB_ST	P04637	TP53	Q96GD4	AURKB	T284	D281H	281	Missense	distal	-3	no	0.077	0.078	PhosphoSitePlus;EPSD	TCGA;ICGC;COSMIC	0.010	Up-regulation
Other_Aur_AurB_ST	P04637	TP53	Q96GD4	AURKB	T284	P278R	278	Missense	distal	-6	no	0.077	0.079	PhosphoSitePlus;EPSD	TCGA;ICGC;COSMIC;CCLE	0.010	Up-regulation
Other_Aur_AurB_ST	P04637	TP53	Q96GD4	AURKB	T284	R280S	280	Missense	distal	-4	no	0.077	0.076	PhosphoSitePlus;EPSD	TCGA;ICGC;COSMIC;GDSC;CCLE	0.010	Down-regulation
Other_Aur_AurB_ST	P04637	TP53	Q96GD4	AURKB	T284	D281Y	281	Missense	distal	-3	no	0.077	0.078	PhosphoSitePlus;EPSD	TCGA;ICGC;COSMIC;GDSC;CCLE	0.010	Up-regulation
Other_Aur_AurB_ST	P04637	TP53	Q96GD4	AURKB	T284	P278S	278	Missense	distal	-6	no	0.077	0.078	PhosphoSitePlus;EPSD	TCGA;ICGC;COSMIC;GDSC;CCLE	0.010	Up-regulation
Other_Aur_AurB_ST	P04637	TP53	Q96GD4	AURKB	T284	P278T	278	Missense	distal	-6	no	0.077	0.078	PhosphoSitePlus;EPSD	TCGA;ICGC;COSMIC	0.010	Up-regulation
Other_Aur_AurB_ST	P04637	TP53	Q96GD4	AURKB	T284	P278H	278	Missense	distal	-6	no	0.077	0.078	PhosphoSitePlus;EPSD	TCGA;ICGC;COSMIC;GDSC;CCLE	0.010	Up-regulation
Other_Aur_AurB_ST	P04637	TP53	Q96GD4	AURKB	T284	R282G	282	Missense	proximal	-2	no	0.077	0.006	PhosphoSitePlus;EPSD	TCGA;ICGC;COSMIC;GDSC;CCLE	0.010	Loss
Other_Aur_AurB_ST	P04637	TP53	Q96GD4	AURKB	T284	D281A	281	Missense	distal	-3	no	0.077	0.078	PhosphoSitePlus;EPSD	TCGA;ICGC;COSMIC	0.010	Up-regulation
Other_Aur_AurB_ST	P04637	TP53	Q96GD4	AURKB	T284	R280G	280	Missense	distal	-4	no	0.077	0.076	PhosphoSitePlus;EPSD	TCGA;ICGC;COSMIC;GDSC;CCLE	0.010	Down-regulation
Other_Aur_AurB_ST	P04637	TP53	Q96GD4	AURKB	T284	R283H	283	Missense	proximal	-1	no	0.077	0.070	PhosphoSitePlus;EPSD	TCGA;ICGC;COSMIC;GDSC;CCLE	0.010	Down-regulation
Other_Aur_AurB_ST	P04637	TP53	Q96GD4	AURKB	T284	R280I	280	Missense	distal	-4	no	0.077	0.076	PhosphoSitePlus;EPSD	TCGA;ICGC;COSMIC	0.010	Down-regulation
Other_Aur_AurB_ST	P04637	TP53	Q96GD4	AURKB	T284	D281N	281	Missense	distal	-3	no	0.077	0.078	PhosphoSitePlus;EPSD	TCGA;ICGC;COSMIC;CCLE	0.010	Up-regulation
Other_Aur_AurB_ST	P04637	TP53	Q96GD4	AURKB	T284	R282Q	282	Missense	proximal	-2	no	0.077	0.004	PhosphoSitePlus;EPSD	TCGA;ICGC;COSMIC;GDSC;CCLE	0.010	Loss
Other_Aur_AurB_ST	P04637	TP53	Q96GD4	AURKB	T284	T284P	284	Missense	central	0	yes	0.077	0.000	PhosphoSitePlus;EPSD	TCGA;ICGC;COSMIC	0.010	Loss
Other_Aur_AurB_ST	P04637	TP53	Q96GD4	AURKB	T377	Q375K	375	Missense	proximal	-2	no	-0.005	0.010	EPSD	TCGA;ICGC;COSMIC	0.010	Gain
Other_Aur_AurB_ST	Q9BQG0	MYBBP1A	Q96GD4	AURKB	S635	R633C	633	Missense	proximal	-2	no	0.076	0.006	EPSD	TCGA;ICGC	0.010	Loss
Other_Aur_AurB_ST	Q9BQG0	MYBBP1A	Q96GD4	AURKB	T637	R633C	633	Missense	distal	-4	no	0.011	0.010	EPSD	TCGA;ICGC	0.010	Down-regulation
Other_Aur_AurB_ST	Q9BQG0	MYBBP1A	Q96GD4	AURKB	S672	R671Q	671	Missense	proximal	-1	no	0.013	0.005	EPSD	TCGA;ICGC;COSMIC	0.010	Loss
Other_Aur_AurB_ST	Q9BQG0	MYBBP1A	Q96GD4	AURKB	S732	E727K	727	Missense	distal	-5	no	0.071	0.072	EPSD	TCGA;ICGC;COSMIC	0.010	Up-regulation
Other_Aur_AurB_ST	Q9BQG0	MYBBP1A	Q96GD4	AURKB	S991	R989H	989	Missense	proximal	-2	no	0.074	0.003	EPSD	TCGA;ICGC	0.010	Loss
Other_Aur_AurB_ST	Q9BQG0	MYBBP1A	Q96GD4	AURKB	S991	P996S	996	Missense	distal	5	no	0.074	0.073	EPSD	TCGA;ICGC;COSMIC	0.010	Down-regulation
Other_Aur_AurB_ST	Q9BQG0	MYBBP1A	Q96GD4	AURKB	T1229	P1228R	1228	Missense	proximal	-1	no	0.002	0.010	EPSD	TCGA;ICGC;COSMIC	0.010	Gain
Other_Aur_AurB_ST	Q9BQG0	MYBBP1A	Q96GD4	AURKB	T1230	P1228R	1228	Missense	proximal	-2	no	-0.006	0.068	EPSD	TCGA;ICGC;COSMIC	0.010	Gain
Other_Aur_AurB_ST	Q9H410	DSN1	Q96GD4	AURKB	S95	R92M	92	Missense	distal	-3	no	0.077	0.070	EPSD	TCGA;ICGC;COSMIC	0.010	Down-regulation
Other_Aur_AurB_ST	Q9H410	DSN1	Q96GD4	AURKB	S109	P112H	112	Missense	distal	3	no	0.080	0.079	PhosphoSitePlus;EPSD	TCGA;ICGC;COSMIC	0.010	Down-regulation
Other_Aur_AurB_ST	Q9H410	DSN1	Q96GD4	AURKB	S109	S109L	109	Missense	central	0	yes	0.080	0.000	PhosphoSitePlus;EPSD	TCGA;ICGC;COSMIC;GDSC;CCLE	0.010	Loss
Other_Aur_AurB_ST	O95239	KIF4A	Q96GD4	AURKB	T250	T250I	250	Missense	central	0	yes	0.014	0.000	EPSD	TCGA;ICGC;COSMIC	0.010	Loss
Other_Aur_AurB_ST	O95239	KIF4A	Q96GD4	AURKB	S291	R295G	295	Missense	distal	4	no	0.071	0.070	EPSD	TCGA;ICGC;COSMIC	0.010	Down-regulation
Other_Aur_AurB_ST	O95239	KIF4A	Q96GD4	AURKB	S291	R289I	289	Missense	proximal	-2	no	0.071	-0.001	EPSD	TCGA;ICGC;COSMIC	0.010	Loss
Other_Aur_AurB_ST	O95239	KIF4A	Q96GD4	AURKB	T294	R295G	295	Missense	proximal	1	no	0.011	0.012	EPSD	TCGA;ICGC;COSMIC	0.010	Up-regulation
Other_Aur_AurB_ST	O95239	KIF4A	Q96GD4	AURKB	T294	K292T	292	Missense	proximal	-2	no	0.011	0.003	EPSD	TCGA;ICGC;COSMIC	0.010	Loss
Other_Aur_AurB_ST	O95239	KIF4A	Q96GD4	AURKB	T294	R289I	289	Missense	distal	-5	no	0.011	0.009	EPSD	TCGA;ICGC;COSMIC	0.010	Loss
Other_Aur_AurB_ST	O95239	KIF4A	Q96GD4	AURKB	T544	A538V	538	Missense	distal	-6	no	0.017	0.016	EPSD	TCGA;ICGC;COSMIC	0.010	Down-regulation
Other_Aur_AurB_ST	O95239	KIF4A	Q96GD4	AURKB	S595	R599H	599	Missense	distal	4	no	0.013	0.012	EPSD	TCGA;ICGC;COSMIC	0.010	Down-regulation
Other_Aur_AurB_ST	O95239	KIF4A	Q96GD4	AURKB	S595	K600R	600	Missense	distal	5	no	0.013	0.012	EPSD	TCGA;ICGC;COSMIC	0.010	Down-regulation
Other_Aur_AurB_ST	O95239	KIF4A	Q96GD4	AURKB	S801	R806C	806	Missense	distal	5	no	0.012	0.014	EPSD	TCGA;ICGC;COSMIC;CCLE	0.010	Up-regulation
Other_Aur_AurB_ST	O95239	KIF4A	Q96GD4	AURKB	S1139	E1137K	1137	Missense	proximal	-2	no	-0.004	0.010	EPSD	TCGA;ICGC;COSMIC	0.010	Gain
Other_Aur_AurB_ST	O95239	KIF4A	Q96GD4	AURKB	T1149	E1147K	1147	Missense	proximal	-2	no	-0.002	0.011	EPSD	TCGA;ICGC;COSMIC	0.010	Gain
Other_Aur_AurB_ST	O95239	KIF4A	Q96GD4	AURKB	T1181	K1179N	1179	Missense	proximal	-2	no	0.012	0.000	EPSD	TCGA;ICGC;COSMIC	0.010	Loss
Other_Aur_AurB_ST	Q53SF7	COBLL1	Q96GD4	AURKB	S414	H412R	412	Missense	proximal	-2	no	-0.003	0.068	EPSD	TCGA;ICGC;COSMIC	0.010	Gain
Other_Aur_AurB_ST	Q8NEY8	PPHLN1	Q96GD4	AURKB	S21	P19L	19	Missense	proximal	-2	no	0.007	0.011	EPSD	TCGA;COSMIC	0.010	Gain
Other_Aur_AurB_ST	Q8NEY8	PPHLN1	Q96GD4	AURKB	S110	R107K	107	Missense	distal	-3	no	0.079	0.073	PhosphoSitePlus	TCGA;COSMIC	0.010	Down-regulation
Other_Aur_AurB_ST	Q8NEY8	PPHLN1	Q96GD4	AURKB	S110	S114Y	114	Missense	distal	4	no	0.079	0.078	PhosphoSitePlus	TCGA;ICGC;COSMIC	0.010	Down-regulation
Other_Aur_AurB_ST	Q8NEY8	PPHLN1	Q96GD4	AURKB	S172	R174H	174	Missense	proximal	2	no	0.070	0.069	EPSD	TCGA;ICGC;COSMIC	0.010	Down-regulation
Other_Aur_AurB_ST	Q8NEY8	PPHLN1	Q96GD4	AURKB	S172	R174C	174	Missense	proximal	2	no	0.070	0.069	EPSD	TCGA;COSMIC;GDSC;CCLE	0.010	Down-regulation
Other_Aur_AurB_ST	Q8NEY8	PPHLN1	Q96GD4	AURKB	S172	S172F	172	Missense	central	0	yes	0.070	0.000	EPSD	TCGA	0.010	Loss
Other_Aur_AurB_ST	Q8NEY8	PPHLN1	Q96GD4	AURKB	S201	S201L	201	Missense	central	0	yes	0.010	0.000	EPSD	TCGA;COSMIC	0.010	Loss
Other_Aur_AurB_ST	Q8NEY8	PPHLN1	Q96GD4	AURKB	T396	R394C	394	Missense	proximal	-2	no	0.076	0.006	EPSD	TCGA;COSMIC	0.010	Loss
Other_Aur_AurB_ST	Q8NEY8	PPHLN1	Q96GD4	AURKB	T397	R394C	394	Missense	distal	-3	no	0.080	0.073	EPSD	TCGA;COSMIC	0.010	Down-regulation
Other_Aur_AurB_ST	Q5UIP0	RIF1	Q96GD4	AURKB	S111	V115A	115	Missense	distal	4	no	0.010	0.011	EPSD	TCGA;ICGC;COSMIC	0.010	Up-regulation
Other_Aur_AurB_ST	Q5UIP0	RIF1	Q96GD4	AURKB	S787	R785K	785	Missense	proximal	-2	no	0.070	0.011	EPSD	TCGA;ICGC;COSMIC	0.010	Down-regulation
Other_Aur_AurB_ST	Q5UIP0	RIF1	Q96GD4	AURKB	S787	S787L	787	Missense	central	0	yes	0.070	0.000	EPSD	TCGA;ICGC;COSMIC	0.010	Loss
Other_Aur_AurB_ST	Q5UIP0	RIF1	Q96GD4	AURKB	S1002	S1002P	1002	Missense	central	0	yes	0.075	0.000	EPSD	TCGA;ICGC;COSMIC	0.010	Loss
Other_Aur_AurB_ST	Q5UIP0	RIF1	Q96GD4	AURKB	S1008	S1008L	1008	Missense	central	0	yes	0.073	0.000	EPSD	TCGA;ICGC;COSMIC	0.010	Loss
Other_Aur_AurB_ST	Q5UIP0	RIF1	Q96GD4	AURKB	T1220	R1217W	1217	Missense	distal	-3	no	0.077	0.070	EPSD	TCGA;ICGC;COSMIC	0.010	Down-regulation
Other_Aur_AurB_ST	Q5UIP0	RIF1	Q96GD4	AURKB	T1220	R1217Q	1217	Missense	distal	-3	no	0.077	0.070	EPSD	TCGA;ICGC;COSMIC	0.010	Down-regulation
Other_Aur_AurB_ST	Q5UIP0	RIF1	Q96GD4	AURKB	S1417	R1420Q	1420	Missense	distal	3	no	0.074	0.075	EPSD	TCGA;ICGC;COSMIC	0.010	Up-regulation
Other_Aur_AurB_ST	Q5UIP0	RIF1	Q96GD4	AURKB	S1417	R1421C	1421	Missense	distal	4	no	0.074	0.073	EPSD	TCGA;ICGC	0.010	Down-regulation
Other_Aur_AurB_ST	Q5UIP0	RIF1	Q96GD4	AURKB	S1418	R1421C	1421	Missense	distal	3	no	0.074	0.075	EPSD	TCGA;ICGC	0.010	Up-regulation
Other_Aur_AurB_ST	Q5UIP0	RIF1	Q96GD4	AURKB	S1422	R1420Q	1420	Missense	proximal	-2	no	0.086	0.012	EPSD	TCGA;ICGC;COSMIC	0.010	Down-regulation
Other_Aur_AurB_ST	Q5UIP0	RIF1	Q96GD4	AURKB	S1422	R1421C	1421	Missense	proximal	-1	no	0.086	0.078	EPSD	TCGA;ICGC	0.010	Down-regulation
Other_Aur_AurB_ST	Q5UIP0	RIF1	Q96GD4	AURKB	S1526	D1523H	1523	Missense	distal	-3	no	0.009	0.010	EPSD	TCGA;ICGC;COSMIC	0.010	Gain
Other_Aur_AurB_ST	Q5UIP0	RIF1	Q96GD4	AURKB	S1542	S1542Y	1542	Missense	central	0	yes	0.075	0.000	EPSD	TCGA	0.010	Loss
Other_Aur_AurB_ST	Q5UIP0	RIF1	Q96GD4	AURKB	T1712	E1710K	1710	Missense	proximal	-2	no	0.000	0.013	EPSD	TCGA;ICGC;COSMIC	0.010	Gain
Other_Aur_AurB_ST	Q5UIP0	RIF1	Q96GD4	AURKB	S1723	R1728S	1728	Missense	distal	5	no	0.019	0.021	EPSD	TCGA;ICGC;COSMIC	0.010	Up-regulation
Other_Aur_AurB_ST	Q5UIP0	RIF1	Q96GD4	AURKB	S1723	K1721T	1721	Missense	proximal	-2	no	0.019	0.010	EPSD	TCGA;ICGC;COSMIC	0.010	Down-regulation
Other_Aur_AurB_ST	Q5UIP0	RIF1	Q96GD4	AURKB	S1869	G1867R	1867	Missense	proximal	-2	no	-0.001	0.071	EPSD	TCGA	0.010	Gain
Other_Aur_AurB_ST	Q5UIP0	RIF1	Q96GD4	AURKB	S2205	R2203C	2203	Missense	proximal	-2	no	0.077	0.007	PhosphoSitePlus	TCGA;ICGC;COSMIC	0.010	Loss
Other_Aur_AurB_ST	Q5UIP0	RIF1	Q96GD4	AURKB	S2205	I2210L	2210	Missense	distal	5	no	0.077	0.078	PhosphoSitePlus	TCGA;ICGC	0.010	Up-regulation
Other_Aur_AurB_ST	Q5UIP0	RIF1	Q96GD4	AURKB	S2205	R2202C	2202	Missense	distal	-3	no	0.077	0.071	PhosphoSitePlus	TCGA;ICGC;COSMIC	0.010	Down-regulation
Other_Aur_AurB_ST	Q5UIP0	RIF1	Q96GD4	AURKB	S2205	R2203H	2203	Missense	proximal	-2	no	0.077	0.007	PhosphoSitePlus	TCGA;ICGC	0.010	Loss
Other_Aur_AurB_ST	Q5UIP0	RIF1	Q96GD4	AURKB	S2224	R2222W	2222	Missense	proximal	-2	no	0.075	0.006	EPSD	TCGA;ICGC;COSMIC;CCLE	0.010	Loss
Other_Aur_AurB_ST	Q5UIP0	RIF1	Q96GD4	AURKB	S2271	S2271L	2271	Missense	central	0	yes	0.012	0.000	EPSD	TCGA	0.010	Loss
Other_Aur_AurB_ST	Q5UIP0	RIF1	Q96GD4	AURKB	S2352	R2347C	2347	Missense	distal	-5	no	0.014	0.012	EPSD	TCGA;COSMIC	0.010	Down-regulation
Other_Aur_AurB_ST	Q08J23	NSUN2	Q96GD4	AURKB	T81	R79S	79	Missense	proximal	-2	no	0.069	-0.004	EPSD	TCGA;ICGC;COSMIC	0.010	Loss
Other_Aur_AurB_ST	Q08J23	NSUN2	Q96GD4	AURKB	T81	R79I	79	Missense	proximal	-2	no	0.069	-0.004	EPSD	TCGA;ICGC	0.010	Loss
Other_Aur_AurB_ST	Q08J23	NSUN2	Q96GD4	AURKB	T81	K84R	84	Missense	distal	3	no	0.069	0.068	EPSD	TCGA;ICGC	0.010	Down-regulation
Other_Aur_AurB_ST	Q08J23	NSUN2	Q96GD4	AURKB	S85	K84R	84	Missense	proximal	-1	no	0.004	0.010	EPSD	TCGA;ICGC	0.010	Gain
Other_Aur_AurB_ST	Q08J23	NSUN2	Q96GD4	AURKB	S139	R133G	133	Missense	distal	-6	no	0.073	0.071	PhosphoSitePlus	TCGA;COSMIC	0.010	Down-regulation
Other_Aur_AurB_ST	Q08J23	NSUN2	Q96GD4	AURKB	S139	K134T	134	Missense	distal	-5	no	0.073	0.072	PhosphoSitePlus	TCGA;COSMIC	0.010	Down-regulation
Other_Aur_AurB_ST	Q08J23	NSUN2	Q96GD4	AURKB	S139	R133Q	133	Missense	distal	-6	no	0.073	0.071	PhosphoSitePlus	TCGA;COSMIC	0.010	Down-regulation
Other_Aur_AurB_ST	Q08J23	NSUN2	Q96GD4	AURKB	S139	S139L	139	Missense	central	0	yes	0.073	0.000	PhosphoSitePlus	TCGA;COSMIC	0.010	Loss
Other_Aur_AurB_ST	Q08J23	NSUN2	Q96GD4	AURKB	S232	H226R	226	Missense	distal	-6	no	0.071	0.072	EPSD	TCGA;COSMIC	0.010	Up-regulation
Other_Aur_AurB_ST	Q08J23	NSUN2	Q96GD4	AURKB	S232	K229N	229	Missense	distal	-3	no	0.071	0.070	EPSD	TCGA;COSMIC	0.010	Down-regulation
Other_Aur_AurB_ST	Q08J23	NSUN2	Q96GD4	AURKB	S233	S233N	233	Missense	central	0	yes	0.010	0.000	EPSD	TCGA;COSMIC	0.010	Loss
Other_Aur_AurB_ST	Q08J23	NSUN2	Q96GD4	AURKB	T466	G463R	463	Missense	distal	-3	no	0.011	0.017	EPSD	TCGA;COSMIC	0.010	Up-regulation
Other_Aur_AurB_ST	Q08J23	NSUN2	Q96GD4	AURKB	T552	R551Q	551	Missense	proximal	-1	no	0.010	0.002	EPSD	TCGA	0.010	Loss
Other_Aur_AurB_ST	O14950	MYL12B	Q96GD4	AURKB	T11	K9E	9	Missense	proximal	-2	no	0.010	-0.003	EPSD	TCGA;ICGC;COSMIC	0.010	Loss
Other_Aur_AurB_ST	O14950	MYL12B	Q96GD4	AURKB	T19	R17C	17	Missense	proximal	-2	no	0.068	-0.003	EPSD	TCGA;ICGC;COSMIC	0.010	Loss
Other_Aur_AurB_ST	O14950	MYL12B	Q96GD4	AURKB	S20	R17C	17	Missense	distal	-3	no	0.012	0.005	PhosphoSitePlus	TCGA;ICGC;COSMIC	0.010	Loss
Other_Aur_AurB_ST	O14950	MYL12B	Q96GD4	AURKB	T160	E158K	158	Missense	proximal	-2	no	-0.004	0.010	EPSD	TCGA;ICGC;COSMIC	0.010	Gain
Other_Aur_AurB_ST	P25490	YY1	Q96GD4	AURKB	S184	G189R	189	Missense	distal	5	no	0.013	0.011	PhosphoSitePlus	TCGA;ICGC;COSMIC	0.010	Down-regulation
Other_Aur_AurB_ST	P25490	YY1	Q96GD4	AURKB	S365	R363H	363	Missense	proximal	-2	no	0.073	0.002	EPSD	TCGA;ICGC	0.010	Loss
Other_Aur_AurB_ST	P25490	YY1	Q96GD4	AURKB	S365	E358K	358	Missense	distal	-7	no	0.073	0.072	EPSD	TCGA;ICGC	0.010	Down-regulation
Other_Aur_AurB_ST	P25490	YY1	Q96GD4	AURKB	T378	H377R	377	Missense	proximal	-1	no	0.004	0.011	EPSD	TCGA	0.010	Gain
Other_Aur_AurB_ST	Q8TEW0	PARD3	Q96GD4	AURKB	S174	R172C	172	Missense	proximal	-2	no	0.072	0.001	EPSD	TCGA;ICGC;COSMIC	0.010	Loss
Other_Aur_AurB_ST	Q8TEW0	PARD3	Q96GD4	AURKB	S383	S386I	386	Missense	distal	3	no	0.067	0.068	EPSD	TCGA;ICGC;COSMIC	0.010	Up-regulation
Other_Aur_AurB_ST	Q8TEW0	PARD3	Q96GD4	AURKB	T468	L464R	464	Missense	distal	-4	no	0.008	0.010	EPSD	TCGA;ICGC;COSMIC	0.010	Gain
Other_Aur_AurB_ST	Q8TEW0	PARD3	Q96GD4	AURKB	S685	R682M	682	Missense	distal	-3	no	0.072	0.065	EPSD	TCGA;ICGC;COSMIC	0.010	Down-regulation
Other_Aur_AurB_ST	Q8TEW0	PARD3	Q96GD4	AURKB	S715	R710K	710	Missense	distal	-5	no	0.081	0.080	EPSD	TCGA;ICGC;COSMIC	0.010	Down-regulation
Other_Aur_AurB_ST	Q8TEW0	PARD3	Q96GD4	AURKB	S715	R712Q	712	Missense	distal	-3	no	0.081	0.074	EPSD	TCGA;ICGC;COSMIC	0.010	Down-regulation
Other_Aur_AurB_ST	Q8TEW0	PARD3	Q96GD4	AURKB	S827	R832H	832	Missense	distal	5	no	0.068	0.070	EPSD	TCGA;COSMIC	0.010	Up-regulation
Other_Aur_AurB_ST	Q8TEW0	PARD3	Q96GD4	AURKB	S827	R825C	825	Missense	proximal	-2	no	0.068	-0.003	EPSD	TCGA	0.010	Loss
Other_Aur_AurB_ST	Q8TEW0	PARD3	Q96GD4	AURKB	T833	R832H	832	Missense	proximal	-1	no	0.021	0.014	EPSD	TCGA;COSMIC	0.010	Down-regulation
Other_Aur_AurB_ST	Q8TEW0	PARD3	Q96GD4	AURKB	S850	K849T	849	Missense	proximal	-1	no	0.070	0.069	EPSD	TCGA;COSMIC	0.010	Down-regulation
Other_Aur_AurB_ST	Q8TEW0	PARD3	Q96GD4	AURKB	S887	K885N	885	Missense	proximal	-2	no	0.013	0.001	EPSD	TCGA	0.010	Loss
Other_Aur_AurB_ST	Q8TEW0	PARD3	Q96GD4	AURKB	S888	K885N	885	Missense	distal	-3	no	0.011	0.009	EPSD	TCGA	0.010	Loss
Other_Aur_AurB_ST	Q8TEW0	PARD3	Q96GD4	AURKB	S962	S962Y	962	Missense	central	0	yes	0.071	0.000	PhosphoSitePlus	TCGA	0.010	Loss
Other_Aur_AurB_ST	Q8TEW0	PARD3	Q96GD4	AURKB	S1107	E1105K	1105	Missense	proximal	-2	no	-0.002	0.011	EPSD	TCGA;COSMIC	0.010	Gain
Other_Aur_AurB_ST	Q8TEW0	PARD3	Q96GD4	AURKB	S1136	S1143G	1143	Missense	distal	7	no	0.071	0.070	EPSD	TCGA;COSMIC	0.010	Down-regulation
Other_Aur_AurB_ST	Q8TEW0	PARD3	Q96GD4	AURKB	S1136	R1134W	1134	Missense	proximal	-2	no	0.071	0.001	EPSD	TCGA;COSMIC	0.010	Loss
Other_Aur_AurB_ST	Q8TEW0	PARD3	Q96GD4	AURKB	S1136	R1134Q	1134	Missense	proximal	-2	no	0.071	-0.003	EPSD	TCGA;COSMIC	0.010	Loss
Other_Aur_AurB_ST	Q8TEW0	PARD3	Q96GD4	AURKB	S1139	R1134W	1134	Missense	distal	-5	no	0.012	0.010	EPSD	TCGA;COSMIC	0.010	Down-regulation
Other_Aur_AurB_ST	Q8TEW0	PARD3	Q96GD4	AURKB	S1139	R1134Q	1134	Missense	distal	-5	no	0.012	0.010	EPSD	TCGA;COSMIC	0.010	Down-regulation
Other_Aur_AurB_ST	Q8TEW0	PARD3	Q96GD4	AURKB	T1176	R1173C	1173	Missense	distal	-3	no	0.085	0.078	EPSD	TCGA;COSMIC	0.010	Down-regulation
Other_Aur_AurB_ST	Q8TEW0	PARD3	Q96GD4	AURKB	T1176	R1175W	1175	Missense	proximal	-1	no	0.085	0.078	EPSD	TCGA;COSMIC	0.010	Down-regulation
Other_Aur_AurB_ST	Q8TEW0	PARD3	Q96GD4	AURKB	S1178	R1173C	1173	Missense	distal	-5	no	0.012	0.010	EPSD	TCGA;COSMIC	0.010	Down-regulation
Other_Aur_AurB_ST	Q8TEW0	PARD3	Q96GD4	AURKB	S1178	R1175W	1175	Missense	distal	-3	no	0.012	0.005	EPSD	TCGA;COSMIC	0.010	Loss
Other_Aur_AurB_ST	Q8TEW0	PARD3	Q96GD4	AURKB	S1196	S1196L	1196	Missense	central	0	yes	0.073	0.000	EPSD	TCGA	0.010	Loss
Other_Aur_AurB_ST	Q8TEW0	PARD3	Q96GD4	AURKB	S1260	R1258W	1258	Missense	proximal	-2	no	0.071	0.002	EPSD	TCGA;COSMIC	0.010	Loss
Other_Aur_AurB_ST	P53350	PLK1	Q96GD4	AURKB	S99	R95M	95	Missense	distal	-4	no	0.014	0.013	EPSD	TCGA;ICGC;COSMIC	0.010	Down-regulation
Other_Aur_AurB_ST	P53350	PLK1	Q96GD4	AURKB	S99	S99F	99	Missense	central	0	yes	0.014	0.000	EPSD	TCGA;ICGC	0.010	Loss
Other_Aur_AurB_ST	P53350	PLK1	Q96GD4	AURKB	S103	E101K	101	Missense	proximal	-2	no	-0.002	0.012	EPSD	TCGA;ICGC;COSMIC	0.010	Gain
Other_Aur_AurB_ST	P53350	PLK1	Q96GD4	AURKB	S137	R134H	134	Missense	distal	-3	no	0.084	0.078	EPSD	TCGA;ICGC	0.010	Down-regulation
Other_Aur_AurB_ST	P53350	PLK1	Q96GD4	AURKB	T210	K208E	208	Missense	proximal	-2	no	0.019	0.006	PhosphoSitePlus	TCGA;ICGC;COSMIC	0.010	Loss
Other_Aur_AurB_ST	P53350	PLK1	Q96GD4	AURKB	S326	S326L	326	Missense	central	0	yes	0.072	0.000	EPSD	TCGA;ICGC;COSMIC;CCLE	0.010	Loss
Other_Aur_AurB_ST	P53350	PLK1	Q96GD4	AURKB	S565	R560H	560	Missense	distal	-5	no	0.075	0.073	EPSD	TCGA;ICGC;COSMIC	0.010	Down-regulation
Other_Aur_AurB_ST	P18615	NELFE	Q96GD4	AURKB	S49	R48C	48	Missense	proximal	-1	no	0.020	0.012	EPSD	TCGA;COSMIC	0.010	Down-regulation
Other_Aur_AurB_ST	P18615	NELFE	Q96GD4	AURKB	S84	R88C	88	Missense	distal	4	no	0.014	0.013	EPSD	TCGA;COSMIC	0.010	Down-regulation
Other_Aur_AurB_ST	P18615	NELFE	Q96GD4	AURKB	S89	S89C	89	Missense	central	0	yes	0.019	0.000	EPSD	TCGA;COSMIC	0.010	Loss
Other_Aur_AurB_ST	P18615	NELFE	Q96GD4	AURKB	S89	R88C	88	Missense	proximal	-1	no	0.019	0.011	EPSD	TCGA;COSMIC	0.010	Down-regulation
Other_Aur_AurB_ST	P18615	NELFE	Q96GD4	AURKB	T91	S89C	89	Missense	proximal	-2	no	0.009	0.012	EPSD	TCGA;COSMIC	0.010	Gain
Other_Aur_AurB_ST	P18615	NELFE	Q96GD4	AURKB	S131	R126H	126	Missense	distal	-5	no	0.078	0.077	PhosphoSitePlus	TCGA	0.010	Down-regulation
Other_Aur_AurB_ST	P18615	NELFE	Q96GD4	AURKB	S131	E134G	134	Missense	distal	3	no	0.078	0.079	PhosphoSitePlus	TCGA;COSMIC	0.010	Up-regulation
Other_Aur_AurB_ST	P18615	NELFE	Q96GD4	AURKB	S191	R194K	194	Missense	distal	3	no	0.013	0.014	EPSD	TCGA;COSMIC	0.010	Up-regulation
Other_Aur_AurB_ST	P18615	NELFE	Q96GD4	AURKB	S249	R255W	255	Missense	distal	6	no	0.075	0.074	EPSD	TCGA	0.010	Down-regulation
Other_Aur_AurB_ST	P18615	NELFE	Q96GD4	AURKB	S249	R256Q	256	Missense	distal	7	no	0.075	0.074	EPSD	TCGA;COSMIC	0.010	Down-regulation
Other_Aur_AurB_ST	Q02241	KIF23	Q96GD4	AURKB	T13	G17R	17	Missense	distal	4	no	0.016	0.017	EPSD	TCGA;ICGC;COSMIC	0.010	Up-regulation
Other_Aur_AurB_ST	Q02241	KIF23	Q96GD4	AURKB	T13	R10W	10	Missense	distal	-3	no	0.016	0.009	EPSD	TCGA;ICGC;COSMIC	0.010	Loss
Other_Aur_AurB_ST	Q02241	KIF23	Q96GD4	AURKB	S18	G17R	17	Missense	proximal	-1	no	0.017	0.025	EPSD	TCGA;ICGC;COSMIC	0.010	Up-regulation
Other_Aur_AurB_ST	Q02241	KIF23	Q96GD4	AURKB	S298	S298F	298	Missense	central	0	yes	0.070	0.000	EPSD	TCGA;COSMIC	0.010	Loss
Other_Aur_AurB_ST	Q02241	KIF23	Q96GD4	AURKB	T679	R673Q	673	Missense	distal	-6	no	0.012	0.010	EPSD	TCGA;COSMIC	0.010	Down-regulation
Other_Aur_AurB_ST	Q02241	KIF23	Q96GD4	AURKB	S714	R713H	713	Missense	proximal	-1	no	0.080	0.073	EPSD	TCGA;ICGC;COSMIC	0.010	Down-regulation
Other_Aur_AurB_ST	Q02241	KIF23	Q96GD4	AURKB	S812	R813H	813	Missense	proximal	1	no	0.081	0.082	EPSD	TCGA;COSMIC	0.010	Up-regulation
Other_Aur_AurB_ST	Q02241	KIF23	Q96GD4	AURKB	S812	R806C	806	Missense	distal	-6	no	0.081	0.080	EPSD	TCGA;COSMIC	0.010	Down-regulation
Other_Aur_AurB_ST	Q02241	KIF23	Q96GD4	AURKB	S812	R806H	806	Missense	distal	-6	no	0.081	0.080	EPSD	TCGA;COSMIC	0.010	Down-regulation
Other_Aur_AurB_ST	Q02241	KIF23	Q96GD4	AURKB	S814	R813H	813	Missense	proximal	-1	no	0.014	0.007	EPSD	TCGA;COSMIC	0.010	Loss
Other_Aur_AurB_ST	Q02241	KIF23	Q96GD4	AURKB	S814	S814F	814	Missense	central	0	yes	0.014	0.000	EPSD	TCGA;COSMIC	0.010	Loss
Other_Aur_AurB_ST	Q02241	KIF23	Q96GD4	AURKB	S943	R940T	940	Missense	distal	-3	no	0.010	0.003	EPSD	TCGA;COSMIC	0.010	Loss
Other_Aur_AurB_ST	Q02241	KIF23	Q96GD4	AURKB	S943	A941V	941	Missense	proximal	-2	no	0.010	0.004	EPSD	TCGA;COSMIC	0.010	Loss
Other_Aur_AurB_ST	O95235	KIF20A	Q96GD4	AURKB	S104	S104Y	104	Missense	central	0	yes	0.013	0.000	EPSD	TCGA;ICGC	0.010	Loss
Other_Aur_AurB_ST	O95235	KIF20A	Q96GD4	AURKB	S244	K242N	242	Missense	proximal	-2	no	0.020	0.008	EPSD	TCGA;COSMIC	0.010	Loss
Other_Aur_AurB_ST	O95235	KIF20A	Q96GD4	AURKB	T328	R324C	324	Missense	distal	-4	no	0.069	0.068	EPSD	TCGA;ICGC;COSMIC;CCLE	0.010	Down-regulation
Other_Aur_AurB_ST	O95235	KIF20A	Q96GD4	AURKB	S608	C607R	607	Missense	proximal	-1	no	0.003	0.011	EPSD	TCGA;COSMIC	0.010	Gain
Other_Aur_AurB_ST	O95235	KIF20A	Q96GD4	AURKB	S632	S635I	635	Missense	distal	3	no	0.009	0.010	EPSD	TCGA;COSMIC	0.010	Gain
Other_Aur_AurB_ST	O95235	KIF20A	Q96GD4	AURKB	S677	R675Q	675	Missense	proximal	-2	no	0.078	0.005	EPSD	TCGA;ICGC;COSMIC	0.010	Loss
Other_Aur_AurB_ST	O95235	KIF20A	Q96GD4	AURKB	S677	R676W	676	Missense	proximal	-1	no	0.078	0.071	EPSD	TCGA;ICGC;COSMIC	0.010	Down-regulation
Other_Aur_AurB_ST	O95235	KIF20A	Q96GD4	AURKB	S878	R877H	877	Missense	proximal	-1	no	0.080	0.073	PhosphoSitePlus	TCGA;ICGC;COSMIC	0.010	Down-regulation
Other_Aur_AurB_ST	Q9Y2I6	NINL	Q96GD4	AURKB	T161	E159K	159	Missense	proximal	-2	no	-0.003	0.010	EPSD	TCGA;ICGC;COSMIC	0.010	Gain
Other_Aur_AurB_ST	Q9Y2I6	NINL	Q96GD4	AURKB	S448	G442R	442	Missense	distal	-6	no	0.072	0.073	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	0.010	Up-regulation
Other_Aur_AurB_ST	Q9Y2I6	NINL	Q96GD4	AURKB	S448	R451L	451	Missense	distal	3	no	0.072	0.073	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	0.010	Up-regulation
Other_Aur_AurB_ST	Q9Y2I6	NINL	Q96GD4	AURKB	S448	R446M	446	Missense	proximal	-2	no	0.072	0.001	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	0.010	Loss
Other_Aur_AurB_ST	Q9Y2I6	NINL	Q96GD4	AURKB	S585	H584L	584	Missense	proximal	-1	no	0.068	0.067	PhosphoSitePlus;EPSD	TCGA;ICGC;COSMIC	0.010	Down-regulation
Other_Aur_AurB_ST	Q9Y2I6	NINL	Q96GD4	AURKB	S1021	G1020W	1020	Missense	proximal	-1	no	0.075	0.076	EPSD	TCGA;ICGC;COSMIC	0.010	Up-regulation
Other_Aur_AurB_ST	Q8WWK9	CKAP2	Q96GD4	AURKB	S124	S124R	124	Missense	central	0	yes	0.013	0.000	EPSD	TCGA;COSMIC	0.010	Loss
Other_Aur_AurB_ST	Q8WWK9	CKAP2	Q96GD4	AURKB	S209	L208R	208	Missense	proximal	-1	no	0.011	0.018	EPSD	TCGA	0.010	Up-regulation
Other_Aur_AurB_ST	Q8WWK9	CKAP2	Q96GD4	AURKB	S303	K301R	301	Missense	proximal	-2	no	0.011	0.070	EPSD	TCGA;COSMIC	0.010	Up-regulation
Other_Aur_AurB_ST	Q8WWK9	CKAP2	Q96GD4	AURKB	S303	K301N	301	Missense	proximal	-2	no	0.011	0.000	EPSD	TCGA;COSMIC	0.010	Loss
Other_Aur_AurB_ST	Q8WWK9	CKAP2	Q96GD4	AURKB	T363	R367T	367	Missense	distal	4	no	0.010	0.009	EPSD	TCGA;COSMIC	0.010	Loss
Other_Aur_AurB_ST	Q8WWK9	CKAP2	Q96GD4	AURKB	S372	R367T	367	Missense	distal	-5	no	0.073	0.071	EPSD	TCGA;COSMIC	0.010	Down-regulation
Other_Aur_AurB_ST	Q8WWK9	CKAP2	Q96GD4	AURKB	S372	R370H	370	Missense	proximal	-2	no	0.073	0.003	EPSD	TCGA;COSMIC	0.010	Loss
Other_Aur_AurB_ST	Q8WWK9	CKAP2	Q96GD4	AURKB	T586	E583K	583	Missense	distal	-3	no	0.009	0.011	EPSD	TCGA;COSMIC	0.010	Gain
Other_Aur_AurB_ST	Q8WWK9	CKAP2	Q96GD4	AURKB	S628	R627C	627	Missense	proximal	-1	no	0.079	0.071	PhosphoSitePlus;EPSD	TCGA;COSMIC	0.010	Down-regulation
Other_Aur_AurB_ST	Q9H6F5	CCDC86	Q96GD4	AURKB	S8	R6S	6	Missense	proximal	-2	no	0.079	0.006	EPSD	TCGA	0.010	Loss
Other_Aur_AurB_ST	Q9H6F5	CCDC86	Q96GD4	AURKB	S66	P59R	59	Missense	distal	-7	no	0.010	0.009	EPSD	TCGA;ICGC;COSMIC	0.010	Loss
Other_Aur_AurB_ST	Q9H6F5	CCDC86	Q96GD4	AURKB	S66	R61K	61	Missense	distal	-5	no	0.010	0.008	EPSD	TCGA;ICGC;COSMIC	0.010	Loss
Other_Aur_AurB_ST	Q9H6F5	CCDC86	Q96GD4	AURKB	S66	P67S	67	Missense	proximal	1	no	0.010	0.009	EPSD	TCGA;ICGC;COSMIC	0.010	Loss
Other_Aur_AurB_ST	Q9H6F5	CCDC86	Q96GD4	AURKB	S121	C116R	116	Missense	distal	-5	no	0.013	0.015	EPSD	TCGA;ICGC;COSMIC	0.010	Up-regulation
Other_Aur_AurB_ST	Q9H6F5	CCDC86	Q96GD4	AURKB	S128	K126Q	126	Missense	proximal	-2	no	0.012	-0.003	EPSD	TCGA;ICGC;COSMIC	0.010	Loss
Other_Aur_AurB_ST	Q9H6F5	CCDC86	Q96GD4	AURKB	T146	E144K	144	Missense	proximal	-2	no	-0.002	0.011	EPSD	TCGA;ICGC;COSMIC	0.010	Gain
Other_Aur_AurB_ST	Q9H6F5	CCDC86	Q96GD4	AURKB	S217	R214Q	214	Missense	distal	-3	no	0.016	0.009	EPSD	TCGA;ICGC;COSMIC	0.010	Loss
Other_Aur_AurB_ST	Q9H6F5	CCDC86	Q96GD4	AURKB	S255	S255F	255	Missense	central	0	yes	0.075	0.000	PhosphoSitePlus	TCGA	0.010	Loss
Other_Aur_AurB_ST	Q9H6F5	CCDC86	Q96GD4	AURKB	S266	S266L	266	Missense	central	0	yes	0.070	0.000	EPSD	TCGA;ICGC;COSMIC;CCLE	0.010	Loss
Other_Aur_AurB_ST	Q9H6F5	CCDC86	Q96GD4	AURKB	S266	R264C	264	Missense	proximal	-2	no	0.070	-0.001	EPSD	TCGA;ICGC;COSMIC	0.010	Loss
Other_Aur_AurB_ST	Q9H6F5	CCDC86	Q96GD4	AURKB	T344	R342W	342	Missense	proximal	-2	no	0.068	-0.001	EPSD	TCGA;ICGC;COSMIC;CCLE	0.010	Loss
Other_Aur_AurB_ST	P06748	NPM1	Q96GD4	AURKB	S48	S43Y	43	Missense	distal	-5	no	0.011	0.010	EPSD	TCGA;ICGC;COSMIC	0.010	Down-regulation
Other_Aur_AurB_ST	P06748	NPM1	Q96GD4	AURKB	T95	E93K	93	Missense	proximal	-2	no	-0.003	0.010	EPSD	TCGA;ICGC	0.010	Gain
Other_Aur_AurB_ST	P06748	NPM1	Q96GD4	AURKB	S217	P216S	216	Missense	proximal	-1	no	0.012	0.013	EPSD	TCGA;ICGC;COSMIC	0.010	Up-regulation
Other_Aur_AurB_ST	P06748	NPM1	Q96GD4	AURKB	T279	I284V	284	Missense	distal	5	no	0.068	0.069	EPSD	TCGA;ICGC;COSMIC	0.010	Up-regulation
Other_Aur_AurB_ST	Q13315	ATM	Q96GD4	AURKB	S47	R45W	45	Missense	proximal	-2	no	0.074	0.005	EPSD	TCGA;ICGC;COSMIC	0.010	Loss
Other_Aur_AurB_ST	Q13315	ATM	Q96GD4	AURKB	S226	K224N	224	Missense	proximal	-2	no	0.014	0.002	EPSD	TCGA;ICGC;COSMIC	0.010	Loss
Other_Aur_AurB_ST	Q13315	ATM	Q96GD4	AURKB	S333	R329T	329	Missense	distal	-4	no	0.014	0.013	EPSD	TCGA;ICGC;COSMIC;CCLE	0.010	Down-regulation
Other_Aur_AurB_ST	Q13315	ATM	Q96GD4	AURKB	S333	R337H	337	Missense	distal	4	no	0.014	0.013	EPSD	TCGA;ICGC;COSMIC	0.010	Down-regulation
Other_Aur_AurB_ST	Q13315	ATM	Q96GD4	AURKB	S333	R337C	337	Missense	distal	4	no	0.014	0.013	EPSD	TCGA;ICGC;COSMIC;GDSC;CCLE	0.010	Down-regulation
Other_Aur_AurB_ST	Q13315	ATM	Q96GD4	AURKB	S333	S333Y	333	Missense	central	0	yes	0.014	0.000	EPSD	TCGA;ICGC	0.010	Loss
Other_Aur_AurB_ST	Q13315	ATM	Q96GD4	AURKB	S644	E642K	642	Missense	proximal	-2	no	0.000	0.013	EPSD	TCGA;ICGC;COSMIC	0.010	Gain
Other_Aur_AurB_ST	Q13315	ATM	Q96GD4	AURKB	S1770	R1768G	1768	Missense	proximal	-2	no	0.070	-0.002	EPSD	TCGA;ICGC;COSMIC	0.010	Loss
Other_Aur_AurB_ST	Q13315	ATM	Q96GD4	AURKB	T1884	R1882Q	1882	Missense	proximal	-2	no	0.067	-0.007	EPSD	TCGA;ICGC;COSMIC	0.010	Loss
Other_Aur_AurB_ST	Q13315	ATM	Q96GD4	AURKB	S1974	R1973I	1973	Missense	proximal	-1	no	0.018	0.011	EPSD	TCGA;ICGC;COSMIC	0.010	Down-regulation
Other_Aur_AurB_ST	Q13315	ATM	Q96GD4	AURKB	S1974	R1973G	1973	Missense	proximal	-1	no	0.018	0.011	EPSD	TCGA;ICGC;COSMIC	0.010	Down-regulation
Other_Aur_AurB_ST	Q13315	ATM	Q96GD4	AURKB	S2408	S2408L	2408	Missense	central	0	yes	0.013	0.000	EPSD	TCGA;ICGC;COSMIC	0.010	Loss
Other_Aur_AurB_ST	Q13315	ATM	Q96GD4	AURKB	T2751	K2749N	2749	Missense	proximal	-2	no	0.018	0.006	EPSD	TCGA;ICGC;COSMIC	0.010	Loss
Other_Aur_AurB_ST	Q13315	ATM	Q96GD4	AURKB	T2751	T2754A	2754	Missense	distal	3	no	0.018	0.017	EPSD	TCGA;ICGC;COSMIC	0.010	Down-regulation
Other_Aur_AurB_ST	Q13315	ATM	Q96GD4	AURKB	S2812	S2812Y	2812	Missense	central	0	yes	0.010	0.000	EPSD	TCGA;ICGC;COSMIC	0.010	Loss
Other_Aur_AurB_ST	P46778	RPL21	Q96GD4	AURKB	S104	R108C	108	Missense	distal	4	no	0.072	0.071	PhosphoSitePlus	TCGA;ICGC	0.010	Down-regulation
Other_Aur_AurB_ST	P08670	VIM	Q96GD4	AURKB	S47	R50H	50	Missense	distal	3	no	0.069	0.070	EPSD	TCGA;ICGC;COSMIC	0.010	Up-regulation
Other_Aur_AurB_ST	P08670	VIM	Q96GD4	AURKB	S66	R71W	71	Missense	distal	5	no	0.068	0.069	EPSD	TCGA;ICGC;COSMIC	0.010	Up-regulation
Other_Aur_AurB_ST	P08670	VIM	Q96GD4	AURKB	S72	R71W	71	Missense	proximal	-1	no	0.015	0.007	EPSD	TCGA;ICGC;COSMIC	0.010	Loss
Other_Aur_AurB_ST	P08670	VIM	Q96GD4	AURKB	S73	R71W	71	Missense	proximal	-2	no	0.068	-0.002	PhosphoSitePlus	TCGA;ICGC;COSMIC	0.010	Loss
Other_Aur_AurB_ST	P08670	VIM	Q96GD4	AURKB	S409	E407K	407	Missense	proximal	-2	no	0.001	0.015	EPSD	TCGA;ICGC;COSMIC	0.010	Gain
Other_Aur_AurB_ST	P08670	VIM	Q96GD4	AURKB	S412	E407K	407	Missense	distal	-5	no	0.068	0.069	EPSD	TCGA;ICGC;COSMIC	0.010	Up-regulation
Other_Aur_AurB_ST	P08670	VIM	Q96GD4	AURKB	T426	R424W	424	Missense	proximal	-2	no	0.070	0.000	EPSD	TCGA;ICGC;COSMIC	0.010	Loss
Other_Aur_AurB_ST	P08670	VIM	Q96GD4	AURKB	S459	E457K	457	Missense	proximal	-2	no	-0.002	0.011	EPSD	TCGA;ICGC;COSMIC;CCLE	0.010	Gain
Other_Aur_AurB_ST	Q9H788	SH2D4A	Q96GD4	AURKB	T116	K115T	115	Missense	proximal	-1	no	0.070	0.069	EPSD	TCGA	0.010	Down-regulation
Other_Aur_AurB_ST	Q9H788	SH2D4A	Q96GD4	AURKB	S261	R259W	259	Missense	proximal	-2	no	0.072	0.002	PhosphoSitePlus	TCGA;ICGC;COSMIC	0.010	Loss
Other_Aur_AurB_ST	Q69YH5	CDCA2	Q96GD4	AURKB	S76	S81L	81	Missense	distal	5	no	0.071	0.072	EPSD	TCGA;ICGC;COSMIC	0.010	Up-regulation
Other_Aur_AurB_ST	Q69YH5	CDCA2	Q96GD4	AURKB	S81	S81L	81	Missense	central	0	yes	0.014	0.000	EPSD	TCGA;ICGC;COSMIC	0.010	Loss
Other_Aur_AurB_ST	Q69YH5	CDCA2	Q96GD4	AURKB	S91	R90C	90	Missense	proximal	-1	no	0.085	0.077	EPSD	TCGA;ICGC	0.010	Down-regulation
Other_Aur_AurB_ST	Q69YH5	CDCA2	Q96GD4	AURKB	S91	R89Q	89	Missense	proximal	-2	no	0.085	0.011	EPSD	TCGA;ICGC;COSMIC	0.010	Down-regulation
Other_Aur_AurB_ST	Q69YH5	CDCA2	Q96GD4	AURKB	S91	R89L	89	Missense	proximal	-2	no	0.085	0.014	EPSD	TCGA;ICGC;COSMIC	0.010	Down-regulation
Other_Aur_AurB_ST	Q69YH5	CDCA2	Q96GD4	AURKB	S91	R90H	90	Missense	proximal	-1	no	0.085	0.078	EPSD	TCGA;ICGC;COSMIC	0.010	Down-regulation
Other_Aur_AurB_ST	Q69YH5	CDCA2	Q96GD4	AURKB	S146	R142I	142	Missense	distal	-4	no	0.070	0.068	EPSD	TCGA;ICGC;COSMIC	0.010	Down-regulation
Other_Aur_AurB_ST	Q69YH5	CDCA2	Q96GD4	AURKB	S146	A151S	151	Missense	distal	5	no	0.070	0.069	EPSD	TCGA;ICGC;COSMIC	0.010	Down-regulation
Other_Aur_AurB_ST	Q69YH5	CDCA2	Q96GD4	AURKB	S146	S146L	146	Missense	central	0	yes	0.070	0.000	EPSD	TCGA;ICGC;COSMIC	0.010	Loss
Other_Aur_AurB_ST	Q69YH5	CDCA2	Q96GD4	AURKB	S146	R144Q	144	Missense	proximal	-2	no	0.070	-0.004	EPSD	TCGA;ICGC;COSMIC	0.010	Loss
Other_Aur_AurB_ST	Q69YH5	CDCA2	Q96GD4	AURKB	T162	E159K	159	Missense	distal	-3	no	0.010	0.011	EPSD	TCGA;ICGC	0.010	Up-regulation
Other_Aur_AurB_ST	Q69YH5	CDCA2	Q96GD4	AURKB	S205	R203K	203	Missense	proximal	-2	no	0.077	0.018	EPSD	TCGA;ICGC;COSMIC	0.010	Down-regulation
Other_Aur_AurB_ST	Q69YH5	CDCA2	Q96GD4	AURKB	S210	S210Y	210	Missense	central	0	yes	0.068	0.000	EPSD	TCGA;ICGC;COSMIC	0.010	Loss
Other_Aur_AurB_ST	Q69YH5	CDCA2	Q96GD4	AURKB	S475	S475L	475	Missense	central	0	yes	0.013	0.000	EPSD	TCGA;ICGC	0.010	Loss
Other_Aur_AurB_ST	Q69YH5	CDCA2	Q96GD4	AURKB	S507	R510I	510	Missense	distal	3	no	0.073	0.074	EPSD	TCGA;ICGC	0.010	Up-regulation
Other_Aur_AurB_ST	Q69YH5	CDCA2	Q96GD4	AURKB	S833	R832H	832	Missense	proximal	-1	no	0.086	0.079	EPSD	TCGA;ICGC;COSMIC	0.010	Down-regulation
Other_Aur_AurB_ST	Q69YH5	CDCA2	Q96GD4	AURKB	S833	R827G	827	Missense	distal	-6	no	0.086	0.085	EPSD	TCGA;ICGC;COSMIC	0.010	Down-regulation
Other_Aur_AurB_ST	Q69YH5	CDCA2	Q96GD4	AURKB	S833	R827T	827	Missense	distal	-6	no	0.086	0.085	EPSD	TCGA;ICGC;COSMIC	0.010	Down-regulation
Other_Aur_AurB_ST	Q69YH5	CDCA2	Q96GD4	AURKB	S833	S833F	833	Missense	central	0	yes	0.086	0.000	EPSD	TCGA;ICGC;COSMIC	0.010	Loss
Other_Aur_AurB_ST	Q69YH5	CDCA2	Q96GD4	AURKB	S886	R883S	883	Missense	distal	-3	no	0.076	0.069	EPSD	TCGA;ICGC;COSMIC	0.010	Down-regulation
Other_Aur_AurB_ST	Q96CF2	CHMP4C	Q96GD4	AURKB	S146	E144K	144	Missense	proximal	-2	no	-0.001	0.012	EPSD	TCGA;ICGC;COSMIC	0.010	Gain
Other_Aur_AurB_ST	Q96CF2	CHMP4C	Q96GD4	AURKB	S210	R209Q	209	Missense	proximal	-1	no	0.080	0.072	EPSD;PhosphoSitePlus	TCGA;ICGC	0.010	Down-regulation
Other_Aur_AurB_ST	Q96CF2	CHMP4C	Q96GD4	AURKB	S210	R217S	217	Missense	distal	7	no	0.080	0.079	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	0.010	Down-regulation
Other_Aur_AurB_ST	Q96CF2	CHMP4C	Q96GD4	AURKB	S214	R209Q	209	Missense	distal	-5	no	0.013	0.012	EPSD;PhosphoSitePlus	TCGA;ICGC	0.010	Down-regulation
Other_Aur_AurB_ST	Q96CF2	CHMP4C	Q96GD4	AURKB	S214	R217S	217	Missense	distal	3	no	0.013	0.014	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	0.010	Up-regulation
Other_Aur_AurB_ST	Q96CF2	CHMP4C	Q96GD4	AURKB	S214	R211Q	211	Missense	distal	-3	no	0.013	0.006	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	0.010	Loss
Other_Aur_AurB_ST	P46783	RPS10	Q96GD4	AURKB	S97	R95H	95	Missense	proximal	-2	no	0.078	0.007	EPSD	TCGA;ICGC;COSMIC	0.010	Loss
Other_Aur_AurB_ST	P46783	RPS10	Q96GD4	AURKB	S97	R95C	95	Missense	proximal	-2	no	0.078	0.007	EPSD	TCGA;ICGC;COSMIC;GDSC;CCLE	0.010	Loss
Other_Aur_AurB_ST	P46783	RPS10	Q96GD4	AURKB	T126	R124T	124	Missense	proximal	-2	no	0.063	-0.004	EPSD	TCGA;ICGC;COSMIC	0.010	Loss
Other_Aur_AurB_ST	P46783	RPS10	Q96GD4	AURKB	S130	R124T	124	Missense	distal	-6	no	0.079	0.078	EPSD	TCGA;ICGC;COSMIC	0.010	Down-regulation
Other_Aur_AurB_ST	Q9Y2R4	DDX52	Q96GD4	AURKB	S258	E253K	253	Missense	distal	-5	no	0.012	0.013	EPSD	TCGA	0.010	Up-regulation
Other_Aur_AurB_ST	Q9Y2R4	DDX52	Q96GD4	AURKB	T585	K590N	590	Missense	distal	5	no	0.011	0.012	EPSD	TCGA;ICGC	0.010	Up-regulation
Other_Aur_AurB_ST	Q96PK6	RBM14	Q96GD4	AURKB	S220	R214C	214	Missense	distal	-6	no	0.083	0.081	EPSD	TCGA;ICGC;COSMIC	0.010	Down-regulation
Other_Aur_AurB_ST	Q96PK6	RBM14	Q96GD4	AURKB	S582	R585Q	585	Missense	distal	3	no	0.071	0.072	EPSD	TCGA;ICGC;COSMIC;GDSC;CCLE	0.010	Up-regulation
Other_Aur_AurB_ST	Q96PK6	RBM14	Q96GD4	AURKB	S582	R580H	580	Missense	proximal	-2	no	0.071	0.001	EPSD	TCGA;ICGC;COSMIC	0.010	Loss
Other_Aur_AurB_ST	Q96PK6	RBM14	Q96GD4	AURKB	S582	R578H	578	Missense	distal	-4	no	0.071	0.070	EPSD	TCGA;ICGC;COSMIC	0.010	Down-regulation
Other_Aur_AurB_ST	Q96PK6	RBM14	Q96GD4	AURKB	S587	R585Q	585	Missense	proximal	-2	no	0.069	-0.005	EPSD	TCGA;ICGC;COSMIC;GDSC;CCLE	0.010	Loss
Other_Aur_AurB_ST	Q96PK6	RBM14	Q96GD4	AURKB	S627	S623L	623	Missense	distal	-4	no	0.073	0.072	EPSD	TCGA;ICGC;COSMIC	0.010	Down-regulation
Other_Aur_AurB_ST	Q96PK6	RBM14	Q96GD4	AURKB	S627	R625C	625	Missense	proximal	-2	no	0.073	0.002	EPSD	TCGA;ICGC;COSMIC	0.010	Loss
Other_Aur_AurB_ST	Q96PK6	RBM14	Q96GD4	AURKB	S627	R626H	626	Missense	proximal	-1	no	0.073	0.065	EPSD	TCGA;ICGC;COSMIC;GDSC;CCLE	0.010	Down-regulation
Other_Aur_AurB_ST	Q96PK6	RBM14	Q96GD4	AURKB	S632	R636C	636	Missense	distal	4	no	0.017	0.016	EPSD	TCGA;ICGC;COSMIC	0.010	Down-regulation
Other_Aur_AurB_ST	Q96PK6	RBM14	Q96GD4	AURKB	S632	R637C	637	Missense	distal	5	no	0.017	0.018	EPSD	TCGA;ICGC	0.010	Up-regulation
Other_Aur_AurB_ST	Q96PK6	RBM14	Q96GD4	AURKB	S632	R626H	626	Missense	distal	-6	no	0.017	0.015	EPSD	TCGA;ICGC;COSMIC;GDSC;CCLE	0.010	Down-regulation
Other_Aur_AurB_ST	Q96PK6	RBM14	Q96GD4	AURKB	S649	S649L	649	Missense	central	0	yes	0.070	0.000	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	0.010	Loss
Other_Aur_AurB_ST	Q5T5U3	ARHGAP21	Q96GD4	AURKB	S982	T980R	980	Missense	proximal	-2	no	0.002	0.069	EPSD	TCGA;ICGC;COSMIC	0.010	Gain
Other_Aur_AurB_ST	P45973	CBX5	Q96GD4	AURKB	T8	K3N	3	Missense	distal	-5	no	0.016	0.015	EPSD	TCGA;ICGC	0.010	Down-regulation
Other_Aur_AurB_ST	Q8IVT2	MISP	Q96GD4	AURKB	T5	V4M	4	Missense	proximal	-1	no	0.067	0.068	EPSD	TCGA;ICGC;COSMIC	0.010	Up-regulation
Other_Aur_AurB_ST	Q8IVT2	MISP	Q96GD4	AURKB	T179	R177Q	177	Missense	proximal	-2	no	0.068	-0.006	EPSD	TCGA;ICGC;COSMIC	0.010	Loss
Other_Aur_AurB_ST	Q8IVT2	MISP	Q96GD4	AURKB	T179	T179M	179	Missense	central	0	yes	0.068	0.000	EPSD	TCGA;ICGC;COSMIC	0.010	Loss
Other_Aur_AurB_ST	Q8IVT2	MISP	Q96GD4	AURKB	S348	R346H	346	Missense	proximal	-2	no	0.069	-0.001	PhosphoSitePlus	TCGA;ICGC;COSMIC	0.010	Loss
Other_Aur_AurB_ST	Q8IVT2	MISP	Q96GD4	AURKB	S348	R353Q	353	Missense	distal	5	no	0.069	0.071	PhosphoSitePlus	TCGA;ICGC;COSMIC	0.010	Up-regulation
Other_Aur_AurB_ST	Q8IVT2	MISP	Q96GD4	AURKB	S348	R346C	346	Missense	proximal	-2	no	0.069	-0.001	PhosphoSitePlus	TCGA;ICGC;COSMIC	0.010	Loss
Other_Aur_AurB_ST	Q8IVT2	MISP	Q96GD4	AURKB	T464	T464M	464	Missense	central	0	yes	0.012	0.000	EPSD	TCGA;ICGC;COSMIC	0.010	Loss
Other_Aur_AurB_ST	Q8IVT2	MISP	Q96GD4	AURKB	T464	P467S	467	Missense	distal	3	no	0.012	0.011	EPSD	TCGA;ICGC	0.010	Down-regulation
Other_Aur_AurB_ST	Q8IVT2	MISP	Q96GD4	AURKB	T464	A458V	458	Missense	distal	-6	no	0.012	0.011	EPSD	TCGA;ICGC;COSMIC;GDSC	0.010	Down-regulation
Other_Aur_AurB_ST	Q8IVT2	MISP	Q96GD4	AURKB	S553	R549K	549	Missense	distal	-4	no	0.075	0.074	EPSD	TCGA;ICGC;COSMIC	0.010	Down-regulation
Other_Aur_AurB_ST	Q8IVT2	MISP	Q96GD4	AURKB	S553	R557W	557	Missense	distal	4	no	0.075	0.074	EPSD	TCGA;ICGC;COSMIC	0.010	Down-regulation
Other_Aur_AurB_ST	Q8IVT2	MISP	Q96GD4	AURKB	S598	T596K	596	Missense	proximal	-2	no	0.005	0.013	EPSD	TCGA;ICGC;COSMIC	0.010	Gain
Other_Aur_AurB_ST	P08238	HSP90AB1	Q96GD4	AURKB	T269	K267N	267	Missense	proximal	-2	no	0.014	0.002	EPSD	TCGA;ICGC;COSMIC	0.010	Loss
Other_Aur_AurB_ST	P08238	HSP90AB1	Q96GD4	AURKB	S452	R456L	456	Missense	distal	4	no	0.079	0.078	PhosphoSitePlus;EPSD	TCGA;ICGC;COSMIC	0.010	Down-regulation
Other_Aur_AurB_ST	P08238	HSP90AB1	Q96GD4	AURKB	S452	R449H	449	Missense	distal	-3	no	0.079	0.073	PhosphoSitePlus;EPSD	TCGA;ICGC;COSMIC	0.010	Down-regulation
Other_Aur_AurB_ST	P08238	HSP90AB1	Q96GD4	AURKB	S452	R448H	448	Missense	distal	-4	no	0.079	0.078	PhosphoSitePlus;EPSD	TCGA;ICGC;COSMIC	0.010	Down-regulation
Other_Aur_AurB_ST	P08238	HSP90AB1	Q96GD4	AURKB	S452	R448C	448	Missense	distal	-4	no	0.079	0.078	PhosphoSitePlus;EPSD	TCGA;ICGC;COSMIC	0.010	Down-regulation
Other_Aur_AurB_ST	Q9UPY8	MAPRE3	Q96GD4	AURKB	S176	R174W	174	Missense	proximal	-2	no	0.072	0.003	PhosphoSitePlus	TCGA;COSMIC	0.010	Loss
Other_Aur_AurB_ST	Q9H211	CDT1	Q96GD4	AURKB	S101	K100N	100	Missense	proximal	-1	no	0.014	0.013	EPSD	TCGA;ICGC;COSMIC	0.010	Down-regulation
Other_Aur_AurB_ST	Q9H211	CDT1	Q96GD4	AURKB	T102	K100N	100	Missense	proximal	-2	no	0.011	0.000	PhosphoSitePlus;EPSD	TCGA;ICGC;COSMIC	0.010	Loss
Other_Aur_AurB_ST	Q9H211	CDT1	Q96GD4	AURKB	S211	P214H	214	Missense	distal	3	no	0.010	0.009	EPSD	TCGA;ICGC;COSMIC	0.010	Loss
Other_Aur_AurB_ST	Q9H211	CDT1	Q96GD4	AURKB	S211	N209S	209	Missense	proximal	-2	no	0.010	0.007	EPSD	TCGA;ICGC;COSMIC	0.010	Loss
Other_Aur_AurB_ST	Q9H211	CDT1	Q96GD4	AURKB	S463	S463G	463	Missense	central	0	yes	0.011	0.000	EPSD	TCGA;ICGC;COSMIC	0.010	Loss
Other_Aur_AurB_ST	Q9H211	CDT1	Q96GD4	AURKB	S463	R459C	459	Missense	distal	-4	no	0.011	0.010	EPSD	TCGA;ICGC;COSMIC;GDSC	0.010	Down-regulation
Other_Aur_AurB_ST	Q9P227	ARHGAP23	Q96GD4	AURKB	S361	A364T	364	Missense	distal	3	no	0.011	0.012	EPSD	TCGA	0.010	Up-regulation
Other_Aur_AurB_ST	Q9P227	ARHGAP23	Q96GD4	AURKB	S361	G366V	366	Missense	distal	5	no	0.011	0.012	EPSD	TCGA	0.010	Up-regulation
Other_Aur_AurB_ST	Q9P227	ARHGAP23	Q96GD4	AURKB	S361	T359S	359	Missense	proximal	-2	no	0.011	0.006	EPSD	TCGA	0.010	Loss
Other_Aur_AurB_ST	Q9P227	ARHGAP23	Q96GD4	AURKB	S610	R608C	608	Missense	proximal	-2	no	0.079	0.009	EPSD	TCGA	0.010	Loss
Other_Aur_AurB_ST	Q9P227	ARHGAP23	Q96GD4	AURKB	S611	R608C	608	Missense	distal	-3	no	0.078	0.071	EPSD	TCGA	0.010	Down-regulation
Other_Aur_AurB_ST	Q9P227	ARHGAP23	Q96GD4	AURKB	S726	A724V	724	Missense	proximal	-2	no	0.015	0.010	EPSD	TCGA	0.010	Down-regulation
Other_Aur_AurB_ST	Q8WWI1	LMO7	Q96GD4	AURKB	S342	P346S	346	Missense	distal	4	no	0.078	0.079	EPSD	TCGA;COSMIC;GDSC	0.010	Up-regulation
Other_Aur_AurB_ST	Q8IX03	WWC1	Q96GD4	AURKB	S33	R38W	38	Missense	distal	5	no	0.009	0.010	EPSD	TCGA;ICGC;COSMIC	0.010	Gain
Other_Aur_AurB_ST	Q8IX03	WWC1	Q96GD4	AURKB	S539	R537C	537	Missense	proximal	-2	no	0.069	-0.001	PhosphoSitePlus	TCGA;ICGC;COSMIC	0.010	Loss
Other_Aur_AurB_ST	Q8IX03	WWC1	Q96GD4	AURKB	S539	P536S	536	Missense	distal	-3	no	0.069	0.070	PhosphoSitePlus	TCGA;ICGC;COSMIC	0.010	Up-regulation
Other_Aur_AurB_ST	Q8IX03	WWC1	Q96GD4	AURKB	T847	E845K	845	Missense	proximal	-2	no	-0.002	0.011	EPSD	TCGA;ICGC;COSMIC	0.010	Gain
Other_Aur_AurB_ST	Q8IX03	WWC1	Q96GD4	AURKB	S922	R926C	926	Missense	distal	4	no	0.073	0.072	EPSD	TCGA;ICGC;COSMIC	0.010	Down-regulation
Other_Aur_AurB_ST	Q8IX03	WWC1	Q96GD4	AURKB	S922	R920L	920	Missense	proximal	-2	no	0.073	0.002	EPSD	TCGA;ICGC;COSMIC	0.010	Loss
Other_Aur_AurB_ST	Q8IX03	WWC1	Q96GD4	AURKB	S931	F930S	930	Missense	proximal	-1	no	0.009	0.010	EPSD	TCGA;ICGC;COSMIC	0.010	Gain
Other_Aur_AurB_ST	Q8IX03	WWC1	Q96GD4	AURKB	S962	R960Q	960	Missense	proximal	-2	no	0.069	-0.005	EPSD	TCGA;ICGC;COSMIC	0.010	Loss
Other_Aur_AurB_ST	Q8IX03	WWC1	Q96GD4	AURKB	S974	R972Q	972	Missense	proximal	-2	no	0.069	-0.004	EPSD	TCGA;ICGC;COSMIC;GDSC	0.010	Loss
Other_Aur_AurB_ST	Q9Y5B9	SUPT16H	Q96GD4	AURKB	S117	S116G	116	Missense	proximal	-1	no	0.013	0.012	EPSD	TCGA;ICGC;COSMIC	0.010	Down-regulation
Other_Aur_AurB_ST	Q9Y5B9	SUPT16H	Q96GD4	AURKB	S128	I125S	125	Missense	distal	-3	no	0.010	0.011	EPSD	TCGA;ICGC;COSMIC	0.010	Up-regulation
Other_Aur_AurB_ST	Q9Y5B9	SUPT16H	Q96GD4	AURKB	S360	E358K	358	Missense	proximal	-2	no	0.006	0.019	EPSD	TCGA;ICGC;COSMIC	0.010	Gain
Other_Aur_AurB_ST	Q9Y5B9	SUPT16H	Q96GD4	AURKB	S455	R456L	456	Missense	proximal	1	no	0.068	0.069	EPSD	TCGA;ICGC;COSMIC	0.010	Up-regulation
Other_Aur_AurB_ST	Q9Y5B9	SUPT16H	Q96GD4	AURKB	S455	G454S	454	Missense	proximal	-1	no	0.068	0.069	EPSD	TCGA;ICGC;COSMIC	0.010	Up-regulation
Other_Aur_AurB_ST	Q9Y5B9	SUPT16H	Q96GD4	AURKB	T494	R492Q	492	Missense	proximal	-2	no	0.073	0.000	PhosphoSitePlus	TCGA;ICGC;COSMIC	0.010	Loss
Other_Aur_AurB_ST	Q9Y5B9	SUPT16H	Q96GD4	AURKB	S508	R506H	506	Missense	proximal	-2	no	0.073	0.003	EPSD	TCGA;ICGC;COSMIC	0.010	Loss
Other_Aur_AurB_ST	Q9Y5B9	SUPT16H	Q96GD4	AURKB	S603	R601Q	601	Missense	proximal	-2	no	0.069	-0.005	EPSD	TCGA;ICGC;COSMIC	0.010	Loss
Other_Aur_AurB_ST	Q9Y5B9	SUPT16H	Q96GD4	AURKB	S986	E984K	984	Missense	proximal	-2	no	-0.001	0.012	EPSD	TCGA;ICGC;COSMIC	0.010	Gain
Other_Aur_AurB_ST	Q9Y5B9	SUPT16H	Q96GD4	AURKB	S1004	R1002Q	1002	Missense	proximal	-2	no	0.074	0.000	EPSD	TCGA;ICGC	0.010	Loss
Other_Aur_AurB_ST	Q9Y5B9	SUPT16H	Q96GD4	AURKB	S1031	R1029C	1029	Missense	proximal	-2	no	0.071	0.000	EPSD	TCGA;ICGC;COSMIC	0.010	Loss
Other_Aur_AurB_ST	Q9Y5B9	SUPT16H	Q96GD4	AURKB	S1031	S1027L	1027	Missense	distal	-4	no	0.071	0.070	EPSD	TCGA;ICGC;COSMIC	0.010	Down-regulation
Other_Aur_AurB_ST	Q92538	GBF1	Q96GD4	AURKB	T77	E75K	75	Missense	proximal	-2	no	-0.002	0.012	EPSD	TCGA;ICGC;COSMIC	0.010	Gain
Other_Aur_AurB_ST	Q92538	GBF1	Q96GD4	AURKB	S1453	R1448P	1448	Missense	distal	-5	no	0.017	0.015	EPSD	TCGA;ICGC;COSMIC	0.010	Down-regulation
Other_Aur_AurB_ST	Q92538	GBF1	Q96GD4	AURKB	S1466	R1471Q	1471	Missense	distal	5	no	0.011	0.013	EPSD	TCGA;ICGC;COSMIC	0.010	Up-regulation
Other_Aur_AurB_ST	Q92538	GBF1	Q96GD4	AURKB	S1475	G1473R	1473	Missense	proximal	-2	no	-0.001	0.071	EPSD	TCGA;ICGC;COSMIC	0.010	Gain
Other_Aur_AurB_ST	Q92538	GBF1	Q96GD4	AURKB	S1587	W1585R	1585	Missense	proximal	-2	no	0.001	0.071	EPSD	TCGA;ICGC	0.010	Gain
Other_Aur_AurB_ST	Q92538	GBF1	Q96GD4	AURKB	T1838	E1836K	1836	Missense	proximal	-2	no	-0.004	0.010	EPSD	TCGA;ICGC;COSMIC;CCLE	0.010	Gain
Other_Aur_AurB_ST	P62917	RPL8	Q96GD4	AURKB	T73	T73M	73	Missense	central	0	yes	0.019	0.000	EPSD	TCGA;ICGC;COSMIC	0.010	Loss
Other_Aur_AurB_ST	Q9Y520	PRRC2C	Q96GD4	AURKB	T402	R400C	400	Missense	proximal	-2	no	0.065	-0.005	EPSD	TCGA;COSMIC	0.010	Loss
Other_Aur_AurB_ST	Q9Y520	PRRC2C	Q96GD4	AURKB	T402	T402P	402	Missense	central	0	yes	0.065	0.000	EPSD	TCGA;COSMIC	0.010	Loss
Other_Aur_AurB_ST	Q9Y520	PRRC2C	Q96GD4	AURKB	T826	P829R	829	Missense	distal	3	no	0.010	0.009	EPSD	TCGA;COSMIC	0.010	Loss
Other_Aur_AurB_ST	Q9Y520	PRRC2C	Q96GD4	AURKB	S913	R911W	911	Missense	proximal	-2	no	0.066	-0.004	EPSD	TCGA;COSMIC	0.010	Loss
Other_Aur_AurB_ST	Q9Y520	PRRC2C	Q96GD4	AURKB	S924	G928A	928	Missense	distal	4	no	0.026	0.027	EPSD	TCGA;COSMIC	0.010	Up-regulation
Other_Aur_AurB_ST	Q9Y520	PRRC2C	Q96GD4	AURKB	S924	R921Q	921	Missense	distal	-3	no	0.026	0.019	EPSD	TCGA;COSMIC	0.010	Down-regulation
Other_Aur_AurB_ST	Q9Y520	PRRC2C	Q96GD4	AURKB	S976	R974L	974	Missense	proximal	-2	no	0.068	-0.003	EPSD	TCGA;COSMIC	0.010	Loss
Other_Aur_AurB_ST	Q9Y520	PRRC2C	Q96GD4	AURKB	S998	R992C	992	Missense	distal	-6	no	0.070	0.069	EPSD	TCGA;COSMIC	0.010	Down-regulation
Other_Aur_AurB_ST	Q9Y520	PRRC2C	Q96GD4	AURKB	S1242	E1241K	1241	Missense	proximal	-1	no	0.009	0.011	EPSD	TCGA;COSMIC	0.010	Gain
Other_Aur_AurB_ST	Q9Y520	PRRC2C	Q96GD4	AURKB	S1246	S1246C	1246	Missense	central	0	yes	0.014	0.000	EPSD	TCGA;COSMIC	0.010	Loss
Other_Aur_AurB_ST	Q9Y520	PRRC2C	Q96GD4	AURKB	S1263	R1261L	1261	Missense	proximal	-2	no	0.073	0.003	EPSD	TCGA;COSMIC	0.010	Loss
Other_Aur_AurB_ST	Q9Y520	PRRC2C	Q96GD4	AURKB	S1360	S1363Y	1363	Missense	distal	3	no	0.072	0.073	EPSD	TCGA;COSMIC	0.010	Up-regulation
Other_Aur_AurB_ST	Q9Y520	PRRC2C	Q96GD4	AURKB	S1363	S1363Y	1363	Missense	central	0	yes	0.075	0.000	EPSD	TCGA;COSMIC	0.010	Loss
Other_Aur_AurB_ST	Q9Y520	PRRC2C	Q96GD4	AURKB	S1542	Q1546R	1546	Missense	distal	4	no	0.019	0.020	EPSD	TCGA;COSMIC	0.010	Up-regulation
Other_Aur_AurB_ST	Q9Y520	PRRC2C	Q96GD4	AURKB	S1624	K1619N	1619	Missense	distal	-5	no	0.012	0.011	EPSD	TCGA;COSMIC	0.010	Down-regulation
Other_Aur_AurB_ST	Q9Y520	PRRC2C	Q96GD4	AURKB	S1624	R1629I	1629	Missense	distal	5	no	0.012	0.014	EPSD	TCGA	0.010	Up-regulation
Other_Aur_AurB_ST	Q9Y520	PRRC2C	Q96GD4	AURKB	S2143	P2142T	2142	Missense	proximal	-1	no	0.010	0.011	EPSD	TCGA	0.010	Up-regulation
Other_Aur_AurB_ST	Q9Y520	PRRC2C	Q96GD4	AURKB	S2143	S2143I	2143	Missense	central	0	yes	0.010	0.000	EPSD	TCGA;COSMIC	0.010	Loss
Other_Aur_AurB_ST	Q9Y520	PRRC2C	Q96GD4	AURKB	S2268	S2268A	2268	Missense	central	0	yes	0.014	0.000	EPSD	TCGA;COSMIC	0.010	Loss
Other_Aur_AurB_ST	Q9Y520	PRRC2C	Q96GD4	AURKB	T2681	T2681I	2681	Missense	central	0	yes	0.068	0.000	EPSD	TCGA;COSMIC	0.010	Loss
Other_Aur_AurB_ST	Q9Y266	NUDC	Q96GD4	AURKB	S274	E272K	272	Missense	proximal	-2	no	-0.002	0.011	EPSD	TCGA;ICGC;COSMIC	0.010	Gain
Other_Aur_AurB_ST	Q9BXS6	NUSAP1	Q96GD4	AURKB	T130	R128S	128	Missense	proximal	-2	no	0.069	-0.004	EPSD	TCGA;COSMIC	0.010	Loss
Other_Aur_AurB_ST	Q9BXS6	NUSAP1	Q96GD4	AURKB	S240	R236T	236	Missense	distal	-4	no	0.069	0.067	PhosphoSitePlus	TCGA;ICGC;COSMIC	0.010	Down-regulation
Other_Aur_AurB_ST	Q9BXS6	NUSAP1	Q96GD4	AURKB	S240	P245L	245	Missense	distal	5	no	0.069	0.068	PhosphoSitePlus	TCGA;ICGC;COSMIC	0.010	Down-regulation
Other_Aur_AurB_ST	Q9BXS6	NUSAP1	Q96GD4	AURKB	S255	S260T	260	Missense	distal	5	no	0.009	0.010	EPSD	TCGA;ICGC;COSMIC	0.010	Gain
Other_Aur_AurB_ST	Q9BXS6	NUSAP1	Q96GD4	AURKB	S273	R272C	272	Missense	proximal	-1	no	0.020	0.012	EPSD	TCGA;ICGC;COSMIC	0.010	Down-regulation
Other_Aur_AurB_ST	Q9BXS6	NUSAP1	Q96GD4	AURKB	S296	R295C	295	Missense	proximal	-1	no	0.018	0.011	EPSD	TCGA;ICGC	0.010	Down-regulation
Other_Aur_AurB_ST	Q9BXS6	NUSAP1	Q96GD4	AURKB	S305	V310M	310	Missense	distal	5	no	0.073	0.072	EPSD	TCGA;ICGC;COSMIC	0.010	Down-regulation
Other_Aur_AurB_ST	Q9BXS6	NUSAP1	Q96GD4	AURKB	S363	D359H	359	Missense	distal	-4	no	0.013	0.014	EPSD	TCGA;ICGC;COSMIC	0.010	Up-regulation
Other_Aur_AurB_ST	Q9NYP9	MIS18A	Q96GD4	AURKB	S36	S36C	36	Missense	central	0	yes	0.071	0.000	PhosphoSitePlus	TCGA;ICGC;COSMIC	0.010	Loss
Other_Aur_AurB_ST	Q9NYP9	MIS18A	Q96GD4	AURKB	S36	R41H	41	Missense	distal	5	no	0.071	0.073	PhosphoSitePlus	TCGA;ICGC;COSMIC;CCLE	0.010	Up-regulation
Other_Aur_AurB_ST	Q9NYP9	MIS18A	Q96GD4	AURKB	S36	S40R	40	Missense	distal	4	no	0.071	0.072	PhosphoSitePlus	TCGA;ICGC;COSMIC	0.010	Up-regulation
Other_Aur_AurB_ST	Q9NYP9	MIS18A	Q96GD4	AURKB	S36	K33R	33	Missense	distal	-3	no	0.071	0.077	PhosphoSitePlus	TCGA;ICGC;COSMIC	0.010	Up-regulation
Other_Aur_AurB_ST	P46013	MKI67	Q96GD4	AURKB	S174	A168V	168	Missense	distal	-6	no	0.014	0.013	EPSD	TCGA;ICGC;COSMIC	0.010	Down-regulation
Other_Aur_AurB_ST	P46013	MKI67	Q96GD4	AURKB	S264	L258Q	258	Missense	distal	-6	no	0.070	0.071	EPSD	TCGA;ICGC;COSMIC	0.010	Up-regulation
Other_Aur_AurB_ST	P46013	MKI67	Q96GD4	AURKB	S292	R290C	290	Missense	proximal	-2	no	0.073	0.002	EPSD	TCGA;ICGC;COSMIC	0.010	Loss
Other_Aur_AurB_ST	P46013	MKI67	Q96GD4	AURKB	S292	S296Y	296	Missense	distal	4	no	0.073	0.072	EPSD	TCGA;ICGC;COSMIC	0.010	Down-regulation
Other_Aur_AurB_ST	P46013	MKI67	Q96GD4	AURKB	S374	R372T	372	Missense	proximal	-2	no	0.074	0.006	PhosphoSitePlus;EPSD	TCGA;ICGC;COSMIC	0.010	Loss
Other_Aur_AurB_ST	P46013	MKI67	Q96GD4	AURKB	S374	R372G	372	Missense	proximal	-2	no	0.074	0.002	PhosphoSitePlus;EPSD	TCGA;ICGC;COSMIC	0.010	Loss
Other_Aur_AurB_ST	P46013	MKI67	Q96GD4	AURKB	S425	R423T	423	Missense	proximal	-2	no	0.074	0.007	EPSD	TCGA;ICGC;COSMIC	0.010	Loss
Other_Aur_AurB_ST	P46013	MKI67	Q96GD4	AURKB	S507	S507F	507	Missense	central	0	yes	0.081	0.000	EPSD	TCGA;COSMIC	0.010	Loss
Other_Aur_AurB_ST	P46013	MKI67	Q96GD4	AURKB	S507	R503I	503	Missense	distal	-4	no	0.081	0.080	EPSD	TCGA	0.010	Down-regulation
Other_Aur_AurB_ST	P46013	MKI67	Q96GD4	AURKB	S538	S538Y	538	Missense	central	0	yes	0.073	0.000	EPSD;PhosphoSitePlus	TCGA;COSMIC	0.010	Loss
Other_Aur_AurB_ST	P46013	MKI67	Q96GD4	AURKB	S598	R596H	596	Missense	proximal	-2	no	0.086	0.016	EPSD	TCGA;COSMIC	0.010	Down-regulation
Other_Aur_AurB_ST	P46013	MKI67	Q96GD4	AURKB	S598	R596C	596	Missense	proximal	-2	no	0.086	0.016	EPSD	TCGA;COSMIC	0.010	Down-regulation
Other_Aur_AurB_ST	P46013	MKI67	Q96GD4	AURKB	S630	S634R	634	Missense	distal	4	no	0.074	0.075	EPSD	TCGA;COSMIC	0.010	Up-regulation
Other_Aur_AurB_ST	P46013	MKI67	Q96GD4	AURKB	S1071	E1070K	1070	Missense	proximal	-1	no	0.016	0.018	EPSD	TCGA	0.010	Up-regulation
Other_Aur_AurB_ST	P46013	MKI67	Q96GD4	AURKB	T1083	R1081H	1081	Missense	proximal	-2	no	0.067	-0.004	EPSD	TCGA;COSMIC	0.010	Loss
Other_Aur_AurB_ST	P46013	MKI67	Q96GD4	AURKB	S1131	C1129R	1129	Missense	proximal	-2	no	0.004	0.074	EPSD	TCGA;COSMIC	0.010	Gain
Other_Aur_AurB_ST	P46013	MKI67	Q96GD4	AURKB	S1272	R1268Q	1268	Missense	distal	-4	no	0.019	0.018	EPSD	TCGA;COSMIC;GDSC;CCLE	0.010	Down-regulation
Other_Aur_AurB_ST	P46013	MKI67	Q96GD4	AURKB	S1272	R1271K	1271	Missense	proximal	-1	no	0.019	0.013	EPSD	TCGA;COSMIC	0.010	Down-regulation
Other_Aur_AurB_ST	P46013	MKI67	Q96GD4	AURKB	T1335	P1333A	1333	Missense	proximal	-2	no	0.003	0.010	EPSD	TCGA;COSMIC	0.010	Gain
Other_Aur_AurB_ST	P46013	MKI67	Q96GD4	AURKB	S1376	E1374K	1374	Missense	proximal	-2	no	0.001	0.014	EPSD	TCGA;COSMIC	0.010	Gain
Other_Aur_AurB_ST	P46013	MKI67	Q96GD4	AURKB	T1437	T1437I	1437	Missense	central	0	yes	0.071	0.000	EPSD	TCGA;COSMIC	0.010	Loss
Other_Aur_AurB_ST	P46013	MKI67	Q96GD4	AURKB	T1484	T1484M	1484	Missense	central	0	yes	0.011	0.000	EPSD	TCGA;COSMIC	0.010	Loss
Other_Aur_AurB_ST	P46013	MKI67	Q96GD4	AURKB	S1514	R1513K	1513	Missense	proximal	-1	no	0.020	0.014	EPSD	TCGA;COSMIC	0.010	Down-regulation
Other_Aur_AurB_ST	P46013	MKI67	Q96GD4	AURKB	T1601	H1600R	1600	Missense	proximal	-1	no	0.004	0.011	EPSD	TCGA;COSMIC	0.010	Gain
Other_Aur_AurB_ST	P46013	MKI67	Q96GD4	AURKB	S1636	K1634N	1634	Missense	proximal	-2	no	0.015	0.003	EPSD	TCGA;COSMIC	0.010	Loss
Other_Aur_AurB_ST	P46013	MKI67	Q96GD4	AURKB	S1736	R1738I	1738	Missense	proximal	2	no	0.011	0.010	EPSD	TCGA;COSMIC	0.010	Down-regulation
Other_Aur_AurB_ST	P46013	MKI67	Q96GD4	AURKB	S1740	R1738I	1738	Missense	proximal	-2	no	0.072	-0.001	EPSD	TCGA;COSMIC	0.010	Loss
Other_Aur_AurB_ST	P46013	MKI67	Q96GD4	AURKB	T1775	R1772W	1772	Missense	distal	-3	no	0.018	0.012	EPSD	TCGA;COSMIC	0.010	Down-regulation
Other_Aur_AurB_ST	P46013	MKI67	Q96GD4	AURKB	T1775	T1775M	1775	Missense	central	0	yes	0.018	0.000	EPSD	TCGA;COSMIC	0.010	Loss
Other_Aur_AurB_ST	P46013	MKI67	Q96GD4	AURKB	S1880	S1880G	1880	Missense	central	0	yes	0.019	0.000	EPSD	TCGA;COSMIC	0.010	Loss
Other_Aur_AurB_ST	P46013	MKI67	Q96GD4	AURKB	S2002	K2000N	2000	Missense	proximal	-2	no	0.011	0.000	EPSD	TCGA;COSMIC	0.010	Loss
Other_Aur_AurB_ST	P46013	MKI67	Q96GD4	AURKB	T2026	K2024N	2024	Missense	proximal	-2	no	0.010	-0.001	EPSD	TCGA;COSMIC	0.010	Loss
Other_Aur_AurB_ST	P46013	MKI67	Q96GD4	AURKB	T2032	Q2027H	2027	Missense	distal	-5	no	0.070	0.071	EPSD	TCGA;COSMIC	0.010	Up-regulation
Other_Aur_AurB_ST	P46013	MKI67	Q96GD4	AURKB	S2045	S2045C	2045	Missense	central	0	yes	0.015	0.000	EPSD	TCGA;COSMIC	0.010	Loss
Other_Aur_AurB_ST	P46013	MKI67	Q96GD4	AURKB	S2045	A2041V	2041	Missense	distal	-4	no	0.015	0.014	EPSD	TCGA;GDSC;CCLE	0.010	Down-regulation
Other_Aur_AurB_ST	P46013	MKI67	Q96GD4	AURKB	T2211	D2208Y	2208	Missense	distal	-3	no	0.011	0.012	EPSD	TCGA	0.010	Up-regulation
Other_Aur_AurB_ST	P46013	MKI67	Q96GD4	AURKB	T2211	T2211R	2211	Missense	central	0	yes	0.011	0.000	EPSD	TCGA;COSMIC	0.010	Loss
Other_Aur_AurB_ST	P46013	MKI67	Q96GD4	AURKB	S2223	R2222I	2222	Missense	proximal	-1	no	0.011	0.003	EPSD	TCGA;COSMIC	0.010	Loss
Other_Aur_AurB_ST	P46013	MKI67	Q96GD4	AURKB	S2242	S2242N	2242	Missense	central	0	yes	0.018	0.000	EPSD	TCGA;COSMIC	0.010	Loss
Other_Aur_AurB_ST	P46013	MKI67	Q96GD4	AURKB	S2242	K2240N	2240	Missense	proximal	-2	no	0.018	0.007	EPSD	TCGA;COSMIC	0.010	Loss
Other_Aur_AurB_ST	P46013	MKI67	Q96GD4	AURKB	S2242	R2241I	2241	Missense	proximal	-1	no	0.018	0.011	EPSD	TCGA	0.010	Down-regulation
Other_Aur_AurB_ST	P46013	MKI67	Q96GD4	AURKB	T2259	R2258Q	2258	Missense	proximal	-1	no	0.026	0.018	EPSD	TCGA;GDSC;CCLE	0.010	Down-regulation
Other_Aur_AurB_ST	P46013	MKI67	Q96GD4	AURKB	S2261	S2261L	2261	Missense	central	0	yes	0.011	0.000	EPSD	TCGA;COSMIC	0.010	Loss
Other_Aur_AurB_ST	P46013	MKI67	Q96GD4	AURKB	S2261	R2258Q	2258	Missense	distal	-3	no	0.011	0.004	EPSD	TCGA;GDSC;CCLE	0.010	Loss
Other_Aur_AurB_ST	P46013	MKI67	Q96GD4	AURKB	T2380	R2377K	2377	Missense	distal	-3	no	0.025	0.020	EPSD	TCGA;COSMIC	0.010	Down-regulation
Other_Aur_AurB_ST	P46013	MKI67	Q96GD4	AURKB	T2380	R2379Q	2379	Missense	proximal	-1	no	0.025	0.018	EPSD	TCGA;COSMIC	0.010	Down-regulation
Other_Aur_AurB_ST	P46013	MKI67	Q96GD4	AURKB	S2382	R2377K	2377	Missense	distal	-5	no	0.011	0.009	EPSD	TCGA;COSMIC	0.010	Loss
Other_Aur_AurB_ST	P46013	MKI67	Q96GD4	AURKB	S2382	R2379Q	2379	Missense	distal	-3	no	0.011	0.004	EPSD	TCGA;COSMIC	0.010	Loss
Other_Aur_AurB_ST	P46013	MKI67	Q96GD4	AURKB	S2463	E2461K	2461	Missense	proximal	-2	no	0.001	0.014	EPSD	TCGA;COSMIC	0.010	Gain
Other_Aur_AurB_ST	P46013	MKI67	Q96GD4	AURKB	S2505	R2503Q	2503	Missense	proximal	-2	no	0.071	-0.003	EPSD	TCGA;COSMIC;GDSC	0.010	Loss
Other_Aur_AurB_ST	P46013	MKI67	Q96GD4	AURKB	T2623	T2623M	2623	Missense	central	0	yes	0.066	0.000	EPSD	TCGA;COSMIC	0.010	Loss
Other_Aur_AurB_ST	P46013	MKI67	Q96GD4	AURKB	S2769	T2773S	2773	Missense	distal	4	no	0.017	0.018	EPSD	TCGA;COSMIC	0.010	Up-regulation
Other_Aur_AurB_ST	P46013	MKI67	Q96GD4	AURKB	T3205	R3203K	3203	Missense	proximal	-2	no	0.073	0.014	EPSD	TCGA;COSMIC	0.010	Down-regulation
Other_Aur_AurB_ST	P46013	MKI67	Q96GD4	AURKB	T3223	T3223M	3223	Missense	central	0	yes	0.062	0.000	EPSD	TCGA;COSMIC	0.010	Loss
Other_Aur_AurB_ST	P46013	MKI67	Q96GD4	AURKB	T3223	R3221I	3221	Missense	proximal	-2	no	0.062	-0.011	EPSD	TCGA	0.010	Loss
Other_Aur_AurB_ST	P46013	MKI67	Q96GD4	AURKB	S3249	R3248T	3248	Missense	proximal	-1	no	0.017	0.010	EPSD	TCGA;COSMIC	0.010	Down-regulation
Other_Aur_AurB_ST	P46013	MKI67	Q96GD4	AURKB	S3249	S3249R	3249	Missense	central	0	yes	0.017	0.000	EPSD	TCGA;COSMIC	0.010	Loss
Other_Aur_AurB_ST	P46013	MKI67	Q96GD4	AURKB	S3253	R3248T	3248	Missense	distal	-5	no	0.073	0.071	EPSD	TCGA;COSMIC	0.010	Down-regulation
Other_Aur_AurB_ST	Q9NS23	RASSF1	Q96GD4	AURKB	T206	R205C	205	Missense	proximal	-1	no	0.084	0.076	EPSD	TCGA;COSMIC	0.010	Down-regulation
Other_Aur_AurB_ST	Q9NS23	RASSF1	Q96GD4	AURKB	S207	R205C	205	Missense	proximal	-2	no	0.078	0.008	EPSD	TCGA;COSMIC	0.010	Loss
Other_Aur_AurB_ST	Q9BW61	DDA1	Q96GD4	AURKB	S28	A27G	27	Missense	proximal	-1	no	0.015	0.014	EPSD	TCGA;ICGC;COSMIC	0.010	Down-regulation
Other_Aur_AurB_ST	Q9BW61	DDA1	Q96GD4	AURKB	S33	S33L	33	Missense	central	0	yes	0.077	0.000	PhosphoSitePlus	TCGA;ICGC;COSMIC	0.010	Loss
Other_Aur_AurB_ST	Q9BW61	DDA1	Q96GD4	AURKB	S33	R31Q	31	Missense	proximal	-2	no	0.077	0.003	PhosphoSitePlus	TCGA;ICGC;COSMIC	0.010	Loss
Other_Aur_AurB_ST	Q9NP77	SSU72	Q96GD4	AURKB	S19	R18Q	18	Missense	proximal	-1	no	0.010	0.002	PhosphoSitePlus	TCGA;ICGC;COSMIC	0.010	Loss
Other_Aur_AurB_ST	O00566	MPHOSPH10	Q96GD4	AURKB	S184	Q182R	182	Missense	proximal	-2	no	-0.002	0.072	EPSD	TCGA;ICGC;COSMIC	0.010	Gain
Other_Aur_AurB_ST	O00566	MPHOSPH10	Q96GD4	AURKB	S198	K197R	197	Missense	proximal	-1	no	0.004	0.010	EPSD	TCGA;ICGC;COSMIC	0.010	Gain
Other_Aur_AurB_ST	O00566	MPHOSPH10	Q96GD4	AURKB	S468	E471K	471	Missense	distal	3	no	0.014	0.013	EPSD	TCGA;ICGC;COSMIC	0.010	Down-regulation
Other_Aur_AurB_ST	O00566	MPHOSPH10	Q96GD4	AURKB	S611	S611C	611	Missense	central	0	yes	0.014	0.000	EPSD	TCGA;ICGC;COSMIC	0.010	Loss
Other_Aur_AurB_ST	O00566	MPHOSPH10	Q96GD4	AURKB	S629	S629F	629	Missense	central	0	yes	0.012	0.000	EPSD	TCGA;ICGC;COSMIC	0.010	Loss
Other_Aur_AurB_ST	Q9NQZ2	UTP3	Q96GD4	AURKB	S150	R146P	146	Missense	distal	-4	no	0.070	0.068	EPSD	TCGA;ICGC;COSMIC	0.010	Down-regulation
Other_Aur_AurB_ST	Q9NQZ2	UTP3	Q96GD4	AURKB	S150	R146Q	146	Missense	distal	-4	no	0.070	0.069	EPSD	TCGA	0.010	Down-regulation
Other_Aur_AurB_ST	Q9NQZ2	UTP3	Q96GD4	AURKB	S462	R460C	460	Missense	proximal	-2	no	0.072	0.001	PhosphoSitePlus	TCGA;ICGC;COSMIC	0.010	Loss
Other_Aur_AurB_ST	P14618	PKM	Q96GD4	AURKB	T45	R43P	43	Missense	proximal	-2	no	0.068	-0.006	PhosphoSitePlus	TCGA;ICGC;COSMIC	0.010	Loss
Other_Aur_AurB_ST	P14618	PKM	Q96GD4	AURKB	T95	K89N	89	Missense	distal	-6	no	0.010	0.009	EPSD	TCGA;ICGC;COSMIC	0.010	Loss
Other_Aur_AurB_ST	P14618	PKM	Q96GD4	AURKB	T95	R92H	92	Missense	distal	-3	no	0.010	0.003	EPSD	TCGA;ICGC;COSMIC	0.010	Loss
Other_Aur_AurB_ST	P14618	PKM	Q96GD4	AURKB	T95	R92C	92	Missense	distal	-3	no	0.010	0.003	EPSD	TCGA;ICGC;GDSC;CCLE	0.010	Loss
Other_Aur_AurB_ST	O15523	DDX3Y	Q96GD4	AURKB	S77	G82R	82	Missense	distal	5	no	0.070	0.068	EPSD	TCGA;ICGC;COSMIC	0.010	Down-regulation
Other_Aur_AurB_ST	O15523	DDX3Y	Q96GD4	AURKB	S101	S101I	101	Missense	central	0	yes	0.013	0.000	EPSD	TCGA;ICGC;COSMIC	0.010	Loss
Other_Aur_AurB_ST	O15523	DDX3Y	Q96GD4	AURKB	S592	R590T	590	Missense	proximal	-2	no	0.068	0.000	PhosphoSitePlus	TCGA;ICGC;COSMIC	0.010	Loss
Other_Aur_AurB_ST	Q8TE77	SSH3	Q96GD4	AURKB	S37	R31Q	31	Missense	distal	-6	no	0.076	0.074	PhosphoSitePlus	TCGA;ICGC;COSMIC	0.010	Down-regulation
Other_Aur_AurB_ST	Q8TE77	SSH3	Q96GD4	AURKB	S37	R34Q	34	Missense	distal	-3	no	0.076	0.069	PhosphoSitePlus	TCGA;ICGC;COSMIC	0.010	Down-regulation
Other_Aur_AurB_ST	Q8TE77	SSH3	Q96GD4	AURKB	S37	R42C	42	Missense	distal	5	no	0.076	0.078	PhosphoSitePlus	TCGA;ICGC;COSMIC	0.010	Up-regulation
Other_Aur_AurB_ST	Q8TE77	SSH3	Q96GD4	AURKB	S385	E383K	383	Missense	proximal	-2	no	0.000	0.014	EPSD	TCGA;ICGC;COSMIC	0.010	Gain
Other_Aur_AurB_ST	Q8TE77	SSH3	Q96GD4	AURKB	S473	R471H	471	Missense	proximal	-2	no	0.073	0.002	EPSD	TCGA;ICGC	0.010	Loss
Other_Aur_AurB_ST	Q15149	PLEC	Q96GD4	AURKB	T113	R112H	112	Missense	proximal	-1	no	0.077	0.070	EPSD	TCGA;ICGC;COSMIC	0.010	Down-regulation
Other_Aur_AurB_ST	Q15149	PLEC	Q96GD4	AURKB	S714	R713Q	713	Missense	proximal	-1	no	0.018	0.010	EPSD	TCGA;COSMIC;GDSC	0.010	Down-regulation
Other_Aur_AurB_ST	Q15149	PLEC	Q96GD4	AURKB	S714	R711W	711	Missense	distal	-3	no	0.018	0.011	EPSD	TCGA;COSMIC	0.010	Down-regulation
Other_Aur_AurB_ST	Q15149	PLEC	Q96GD4	AURKB	S714	A712V	712	Missense	proximal	-2	no	0.018	0.012	EPSD	TCGA;COSMIC	0.010	Down-regulation
Other_Aur_AurB_ST	Q15149	PLEC	Q96GD4	AURKB	S794	R800W	800	Missense	distal	6	no	0.011	0.010	EPSD	TCGA;COSMIC	0.010	Down-regulation
Other_Aur_AurB_ST	Q15149	PLEC	Q96GD4	AURKB	S887	R890C	890	Missense	distal	3	no	0.018	0.019	EPSD	TCGA;COSMIC;CCLE	0.010	Up-regulation
Other_Aur_AurB_ST	Q15149	PLEC	Q96GD4	AURKB	S1045	R1044H	1044	Missense	proximal	-1	no	0.010	0.003	EPSD	TCGA;COSMIC	0.010	Loss
Other_Aur_AurB_ST	Q15149	PLEC	Q96GD4	AURKB	S1124	R1121C	1121	Missense	distal	-3	no	0.013	0.006	EPSD	TCGA;COSMIC	0.010	Loss
Other_Aur_AurB_ST	Q15149	PLEC	Q96GD4	AURKB	S1124	R1130W	1130	Missense	distal	6	no	0.013	0.012	EPSD	TCGA;COSMIC	0.010	Down-regulation
Other_Aur_AurB_ST	Q15149	PLEC	Q96GD4	AURKB	S1181	S1181F	1181	Missense	central	0	yes	0.070	0.000	EPSD	TCGA;COSMIC	0.010	Loss
Other_Aur_AurB_ST	Q15149	PLEC	Q96GD4	AURKB	S1352	E1351K	1351	Missense	proximal	-1	no	0.074	0.076	EPSD	TCGA;COSMIC	0.010	Up-regulation
Other_Aur_AurB_ST	Q15149	PLEC	Q96GD4	AURKB	S1352	R1347C	1347	Missense	distal	-5	no	0.074	0.073	EPSD	TCGA;COSMIC	0.010	Down-regulation
Other_Aur_AurB_ST	Q15149	PLEC	Q96GD4	AURKB	S2090	R2087C	2087	Missense	distal	-3	no	0.013	0.006	EPSD	TCGA;COSMIC;CCLE	0.010	Loss
Other_Aur_AurB_ST	Q15149	PLEC	Q96GD4	AURKB	S2090	R2089C	2089	Missense	proximal	-1	no	0.013	0.005	EPSD	TCGA;COSMIC	0.010	Loss
Other_Aur_AurB_ST	Q15149	PLEC	Q96GD4	AURKB	S2421	A2417V	2417	Missense	distal	-4	no	0.067	0.066	EPSD	TCGA;COSMIC	0.010	Down-regulation
Other_Aur_AurB_ST	Q15149	PLEC	Q96GD4	AURKB	T2498	E2496K	2496	Missense	proximal	-2	no	-0.003	0.010	EPSD	TCGA;COSMIC	0.010	Gain
Other_Aur_AurB_ST	Q15149	PLEC	Q96GD4	AURKB	S2791	Q2796R	2796	Missense	distal	5	no	0.020	0.018	EPSD	TCGA;COSMIC	0.010	Down-regulation
Other_Aur_AurB_ST	Q15149	PLEC	Q96GD4	AURKB	S2834	R2832L	2832	Missense	proximal	-2	no	0.068	-0.002	EPSD	TCGA	0.010	Loss
Other_Aur_AurB_ST	Q15149	PLEC	Q96GD4	AURKB	S2834	R2832C	2832	Missense	proximal	-2	no	0.068	-0.002	EPSD	TCGA;COSMIC	0.010	Loss
Other_Aur_AurB_ST	Q15149	PLEC	Q96GD4	AURKB	T2886	R2884Q	2884	Missense	proximal	-2	no	0.078	0.004	PhosphoSitePlus	TCGA;COSMIC	0.010	Loss
Other_Aur_AurB_ST	Q15149	PLEC	Q96GD4	AURKB	T2886	A2890T	2890	Missense	distal	4	no	0.078	0.077	PhosphoSitePlus	TCGA;COSMIC	0.010	Down-regulation
Other_Aur_AurB_ST	Q15149	PLEC	Q96GD4	AURKB	T3088	R3083C	3083	Missense	distal	-5	no	0.067	0.065	EPSD	TCGA;COSMIC	0.010	Down-regulation
Other_Aur_AurB_ST	Q15149	PLEC	Q96GD4	AURKB	S3143	R3139Q	3139	Missense	distal	-4	no	0.012	0.011	EPSD	TCGA;COSMIC	0.010	Down-regulation
Other_Aur_AurB_ST	Q15149	PLEC	Q96GD4	AURKB	T3370	R3368C	3368	Missense	proximal	-2	no	0.070	0.000	EPSD	TCGA;COSMIC	0.010	Loss
Other_Aur_AurB_ST	Q15149	PLEC	Q96GD4	AURKB	S3441	R3446L	3446	Missense	distal	5	no	0.069	0.071	EPSD	TCGA;COSMIC	0.010	Up-regulation
Other_Aur_AurB_ST	Q15149	PLEC	Q96GD4	AURKB	T3785	R3783C	3783	Missense	proximal	-2	no	0.073	0.003	EPSD	TCGA;COSMIC	0.010	Loss
Other_Aur_AurB_ST	Q15149	PLEC	Q96GD4	AURKB	T3785	R3781C	3781	Missense	distal	-4	no	0.073	0.072	EPSD	TCGA;COSMIC	0.010	Down-regulation
Other_Aur_AurB_ST	Q15149	PLEC	Q96GD4	AURKB	T3785	R3783L	3783	Missense	proximal	-2	no	0.073	0.003	EPSD	TCGA;COSMIC	0.010	Loss
Other_Aur_AurB_ST	Q15149	PLEC	Q96GD4	AURKB	T3840	R3838S	3838	Missense	proximal	-2	no	0.068	-0.005	EPSD	TCGA;COSMIC	0.010	Loss
Other_Aur_AurB_ST	Q15149	PLEC	Q96GD4	AURKB	T4021	R4018H	4018	Missense	distal	-3	no	0.015	0.009	EPSD	TCGA;COSMIC	0.010	Loss
Other_Aur_AurB_ST	Q15149	PLEC	Q96GD4	AURKB	T4021	R4018C	4018	Missense	distal	-3	no	0.015	0.008	EPSD	TCGA;COSMIC	0.010	Loss
Other_Aur_AurB_ST	Q15149	PLEC	Q96GD4	AURKB	S4268	S4268A	4268	Missense	central	0	yes	0.017	0.000	EPSD	TCGA;COSMIC	0.010	Loss
Other_Aur_AurB_ST	Q15149	PLEC	Q96GD4	AURKB	S4272	S4272Y	4272	Missense	central	0	yes	0.010	0.000	EPSD	TCGA;COSMIC	0.010	Loss
Other_Aur_AurB_ST	Q15149	PLEC	Q96GD4	AURKB	S4272	R4276C	4276	Missense	distal	4	no	0.010	0.009	EPSD	TCGA;COSMIC	0.010	Loss
Other_Aur_AurB_ST	Q15149	PLEC	Q96GD4	AURKB	S4336	R4335H	4335	Missense	proximal	-1	no	0.079	0.072	EPSD	TCGA;COSMIC;GDSC;CCLE	0.010	Down-regulation
Other_Aur_AurB_ST	Q15149	PLEC	Q96GD4	AURKB	S4384	R4381H	4381	Missense	distal	-3	no	0.011	0.005	EPSD	TCGA;COSMIC;GDSC;CCLE	0.010	Loss
Other_Aur_AurB_ST	Q15149	PLEC	Q96GD4	AURKB	S4384	S4389F	4389	Missense	distal	5	no	0.011	0.012	EPSD	TCGA;COSMIC	0.010	Up-regulation
Other_Aur_AurB_ST	Q15149	PLEC	Q96GD4	AURKB	S4385	R4381H	4381	Missense	distal	-4	no	0.074	0.073	EPSD	TCGA;COSMIC;GDSC;CCLE	0.010	Down-regulation
Other_Aur_AurB_ST	Q15149	PLEC	Q96GD4	AURKB	S4506	R4500C	4500	Missense	distal	-6	no	0.014	0.013	EPSD	TCGA;COSMIC	0.010	Down-regulation
Other_Aur_AurB_ST	Q15149	PLEC	Q96GD4	AURKB	S4506	K4504N	4504	Missense	proximal	-2	no	0.014	0.002	EPSD	TCGA	0.010	Loss
Other_Aur_AurB_ST	Q15149	PLEC	Q96GD4	AURKB	S4638	A4636V	4636	Missense	proximal	-2	no	0.010	0.005	EPSD	TCGA;COSMIC	0.010	Loss
Other_Aur_AurB_ST	Q96E39	RBMXL1	Q96GD4	AURKB	S141	N139K	139	Missense	proximal	-2	no	0.001	0.012	EPSD	TCGA;ICGC;COSMIC	0.010	Gain
Other_Aur_AurB_ST	Q96E39	RBMXL1	Q96GD4	AURKB	S165	P160R	160	Missense	distal	-5	no	0.020	0.022	EPSD	TCGA;ICGC;COSMIC	0.010	Up-regulation
Other_Aur_AurB_ST	Q96E39	RBMXL1	Q96GD4	AURKB	S165	P162S	162	Missense	distal	-3	no	0.020	0.021	EPSD	TCGA;ICGC;COSMIC	0.010	Up-regulation
Other_Aur_AurB_ST	Q96E39	RBMXL1	Q96GD4	AURKB	S174	R172C	172	Missense	proximal	-2	no	0.073	0.003	EPSD	TCGA;ICGC;COSMIC;CCLE	0.010	Loss
Other_Aur_AurB_ST	Q96E39	RBMXL1	Q96GD4	AURKB	S174	R172H	172	Missense	proximal	-2	no	0.073	0.003	EPSD	TCGA;ICGC;COSMIC	0.010	Loss
Other_Aur_AurB_ST	Q96E39	RBMXL1	Q96GD4	AURKB	S174	G178R	178	Missense	distal	4	no	0.073	0.074	EPSD	TCGA;ICGC	0.010	Up-regulation
Other_Aur_AurB_ST	Q96E39	RBMXL1	Q96GD4	AURKB	S189	S189N	189	Missense	central	0	yes	0.072	0.000	EPSD	TCGA;ICGC	0.010	Loss
Other_Aur_AurB_ST	Q96E39	RBMXL1	Q96GD4	AURKB	S189	R185C	185	Missense	distal	-4	no	0.072	0.071	EPSD	TCGA;ICGC;COSMIC	0.010	Down-regulation
Other_Aur_AurB_ST	Q96E39	RBMXL1	Q96GD4	AURKB	S219	R223T	223	Missense	distal	4	no	0.013	0.012	EPSD	TCGA;ICGC	0.010	Down-regulation
Other_Aur_AurB_ST	Q96E39	RBMXL1	Q96GD4	AURKB	S219	Y214F	214	Missense	distal	-5	no	0.013	0.012	EPSD	TCGA;ICGC;COSMIC	0.010	Down-regulation
Other_Aur_AurB_ST	Q96E39	RBMXL1	Q96GD4	AURKB	S219	S215P	215	Missense	distal	-4	no	0.013	0.012	EPSD	TCGA;ICGC	0.010	Down-regulation
Other_Aur_AurB_ST	Q96E39	RBMXL1	Q96GD4	AURKB	S326	R331Q	331	Missense	distal	5	no	0.066	0.068	PhosphoSitePlus	TCGA;ICGC;COSMIC	0.010	Up-regulation
Other_Aur_AurB_ST	Q96E39	RBMXL1	Q96GD4	AURKB	S362	R360H	360	Missense	proximal	-2	no	0.070	0.000	EPSD	TCGA;ICGC;COSMIC;GDSC;CCLE	0.010	Loss
Other_Aur_AurB_ST	Q09666	AHNAK	Q96GD4	AURKB	T152	R149H	149	Missense	distal	-3	no	0.011	0.004	EPSD	TCGA;ICGC;COSMIC	0.010	Loss
Other_Aur_AurB_ST	Q09666	AHNAK	Q96GD4	AURKB	T158	R155K	155	Missense	distal	-3	no	0.072	0.067	PhosphoSitePlus	TCGA;ICGC;COSMIC	0.010	Down-regulation
Other_Aur_AurB_ST	Q09666	AHNAK	Q96GD4	AURKB	S758	P755S	755	Missense	distal	-3	no	0.010	0.011	EPSD	TCGA;ICGC;COSMIC	0.010	Up-regulation
Other_Aur_AurB_ST	Q09666	AHNAK	Q96GD4	AURKB	S819	P816S	816	Missense	distal	-3	no	0.010	0.011	EPSD	TCGA;ICGC;COSMIC;CCLE	0.010	Up-regulation
Other_Aur_AurB_ST	Q09666	AHNAK	Q96GD4	AURKB	S947	P944S	944	Missense	distal	-3	no	0.011	0.012	EPSD	TCGA;ICGC;COSMIC	0.010	Up-regulation
Other_Aur_AurB_ST	Q09666	AHNAK	Q96GD4	AURKB	S1007	P1004S	1004	Missense	distal	-3	no	0.010	0.011	EPSD	TCGA;ICGC;COSMIC	0.010	Up-regulation
Other_Aur_AurB_ST	Q09666	AHNAK	Q96GD4	AURKB	S1068	K1066N	1066	Missense	proximal	-2	no	0.012	0.000	EPSD	TCGA;ICGC;COSMIC	0.010	Loss
Other_Aur_AurB_ST	Q09666	AHNAK	Q96GD4	AURKB	S1196	P1193L	1193	Missense	distal	-3	no	0.010	0.011	EPSD	TCGA;ICGC;COSMIC	0.010	Up-regulation
Other_Aur_AurB_ST	Q09666	AHNAK	Q96GD4	AURKB	S1391	P1388A	1388	Missense	distal	-3	no	0.010	0.011	EPSD	TCGA;ICGC;COSMIC	0.010	Up-regulation
Other_Aur_AurB_ST	Q09666	AHNAK	Q96GD4	AURKB	S1391	F1390S	1390	Missense	proximal	-1	no	0.010	0.011	EPSD	TCGA;ICGC;COSMIC	0.010	Up-regulation
Other_Aur_AurB_ST	Q09666	AHNAK	Q96GD4	AURKB	S1519	K1514N	1514	Missense	distal	-5	no	0.011	0.010	EPSD	TCGA;ICGC;COSMIC	0.010	Down-regulation
Other_Aur_AurB_ST	Q09666	AHNAK	Q96GD4	AURKB	S1519	P1516T	1516	Missense	distal	-3	no	0.011	0.012	EPSD	TCGA;ICGC;COSMIC	0.010	Up-regulation
Other_Aur_AurB_ST	Q09666	AHNAK	Q96GD4	AURKB	S1721	K1719N	1719	Missense	proximal	-2	no	0.011	-0.001	EPSD	TCGA;ICGC;COSMIC	0.010	Loss
Other_Aur_AurB_ST	Q09666	AHNAK	Q96GD4	AURKB	S1856	S1856C	1856	Missense	central	0	yes	0.011	0.000	EPSD	TCGA;ICGC;COSMIC	0.010	Loss
Other_Aur_AurB_ST	Q09666	AHNAK	Q96GD4	AURKB	S1856	K1854T	1854	Missense	proximal	-2	no	0.011	0.002	EPSD	TCGA;ICGC	0.010	Loss
Other_Aur_AurB_ST	Q09666	AHNAK	Q96GD4	AURKB	S1990	S1990F	1990	Missense	central	0	yes	0.010	0.000	EPSD	TCGA;ICGC;COSMIC	0.010	Loss
Other_Aur_AurB_ST	Q09666	AHNAK	Q96GD4	AURKB	S2118	I2117V	2117	Missense	proximal	-1	no	0.011	0.010	EPSD	TCGA;ICGC;COSMIC	0.010	Down-regulation
Other_Aur_AurB_ST	Q09666	AHNAK	Q96GD4	AURKB	S2185	S2185F	2185	Missense	central	0	yes	0.010	0.000	EPSD	TCGA;ICGC;COSMIC	0.010	Loss
Other_Aur_AurB_ST	Q09666	AHNAK	Q96GD4	AURKB	S2185	P2182S	2182	Missense	distal	-3	no	0.010	0.011	EPSD	TCGA;ICGC;COSMIC	0.010	Up-regulation
Other_Aur_AurB_ST	Q09666	AHNAK	Q96GD4	AURKB	S2580	S2580F	2580	Missense	central	0	yes	0.011	0.000	EPSD	TCGA;ICGC;COSMIC	0.010	Loss
Other_Aur_AurB_ST	Q09666	AHNAK	Q96GD4	AURKB	S2708	S2708C	2708	Missense	central	0	yes	0.011	0.000	EPSD	TCGA;ICGC;COSMIC	0.010	Loss
Other_Aur_AurB_ST	Q09666	AHNAK	Q96GD4	AURKB	S2708	S2708F	2708	Missense	central	0	yes	0.011	0.000	EPSD	TCGA;ICGC;COSMIC	0.010	Loss
Other_Aur_AurB_ST	Q09666	AHNAK	Q96GD4	AURKB	S2836	K2834N	2834	Missense	proximal	-2	no	0.012	0.000	EPSD	TCGA;ICGC;COSMIC	0.010	Loss
Other_Aur_AurB_ST	Q09666	AHNAK	Q96GD4	AURKB	S3031	K3026N	3026	Missense	distal	-5	no	0.011	0.010	EPSD	TCGA;ICGC;COSMIC	0.010	Down-regulation
Other_Aur_AurB_ST	Q09666	AHNAK	Q96GD4	AURKB	S3294	S3294C	3294	Missense	central	0	yes	0.010	0.000	EPSD	TCGA;ICGC;COSMIC	0.010	Loss
Other_Aur_AurB_ST	Q09666	AHNAK	Q96GD4	AURKB	S3294	P3291S	3291	Missense	distal	-3	no	0.010	0.011	EPSD	TCGA;ICGC;COSMIC	0.010	Up-regulation
Other_Aur_AurB_ST	Q09666	AHNAK	Q96GD4	AURKB	S3416	S3416F	3416	Missense	central	0	yes	0.011	0.000	EPSD	TCGA;ICGC;COSMIC	0.010	Loss
Other_Aur_AurB_ST	Q09666	AHNAK	Q96GD4	AURKB	S3483	E3490K	3490	Missense	distal	7	no	0.010	0.011	EPSD	TCGA;ICGC;COSMIC	0.010	Up-regulation
Other_Aur_AurB_ST	Q09666	AHNAK	Q96GD4	AURKB	S3544	S3544F	3544	Missense	central	0	yes	0.011	0.000	EPSD	TCGA;ICGC	0.010	Loss
Other_Aur_AurB_ST	Q09666	AHNAK	Q96GD4	AURKB	S3611	S3611G	3611	Missense	central	0	yes	0.011	0.000	EPSD	TCGA;ICGC;COSMIC	0.010	Loss
Other_Aur_AurB_ST	Q09666	AHNAK	Q96GD4	AURKB	S3672	S3672F	3672	Missense	central	0	yes	0.011	0.000	EPSD	TCGA;ICGC;COSMIC	0.010	Loss
Other_Aur_AurB_ST	Q09666	AHNAK	Q96GD4	AURKB	S3874	D3879H	3879	Missense	distal	5	no	0.011	0.010	EPSD	TCGA;ICGC;COSMIC	0.010	Down-regulation
Other_Aur_AurB_ST	Q09666	AHNAK	Q96GD4	AURKB	S3941	K3939M	3939	Missense	proximal	-2	no	0.010	-0.002	EPSD	TCGA;ICGC;COSMIC	0.010	Loss
Other_Aur_AurB_ST	Q09666	AHNAK	Q96GD4	AURKB	S4069	K4067R	4067	Missense	proximal	-2	no	0.010	0.069	EPSD	TCGA;ICGC	0.010	Up-regulation
Other_Aur_AurB_ST	Q09666	AHNAK	Q96GD4	AURKB	S4258	K4256E	4256	Missense	proximal	-2	no	0.011	-0.003	EPSD	TCGA;ICGC;COSMIC	0.010	Loss
Other_Aur_AurB_ST	Q09666	AHNAK	Q96GD4	AURKB	S4258	K4256N	4256	Missense	proximal	-2	no	0.011	-0.001	EPSD	TCGA;ICGC	0.010	Loss
Other_Aur_AurB_ST	Q09666	AHNAK	Q96GD4	AURKB	S4386	S4386F	4386	Missense	central	0	yes	0.011	0.000	EPSD	TCGA;ICGC;COSMIC	0.010	Loss
Other_Aur_AurB_ST	Q09666	AHNAK	Q96GD4	AURKB	S4594	S4594C	4594	Missense	central	0	yes	0.011	0.000	EPSD	TCGA;ICGC;COSMIC	0.010	Loss
Other_Aur_AurB_ST	Q09666	AHNAK	Q96GD4	AURKB	S4594	K4592N	4592	Missense	proximal	-2	no	0.011	-0.001	EPSD	TCGA	0.010	Loss
Other_Aur_AurB_ST	Q09666	AHNAK	Q96GD4	AURKB	S4661	P4658L	4658	Missense	distal	-3	no	0.010	0.011	EPSD	TCGA;ICGC;COSMIC	0.010	Up-regulation
Other_Aur_AurB_ST	Q09666	AHNAK	Q96GD4	AURKB	S4789	K4787N	4787	Missense	proximal	-2	no	0.010	-0.001	EPSD	TCGA;ICGC;COSMIC	0.010	Loss
Other_Aur_AurB_ST	Q09666	AHNAK	Q96GD4	AURKB	S5448	S5448L	5448	Missense	central	0	yes	0.071	0.000	EPSD	TCGA;ICGC;COSMIC	0.010	Loss
Other_Aur_AurB_ST	Q09666	AHNAK	Q96GD4	AURKB	S5464	K5462E	5462	Missense	proximal	-2	no	0.012	-0.001	EPSD	TCGA;ICGC;COSMIC	0.010	Loss
Other_Aur_AurB_ST	Q09666	AHNAK	Q96GD4	AURKB	S5769	K5767E	5767	Missense	proximal	-2	no	0.011	-0.002	EPSD	TCGA;ICGC;COSMIC	0.010	Loss
Other_Aur_AurB_ST	Q09666	AHNAK	Q96GD4	AURKB	T5839	E5837K	5837	Missense	proximal	-2	no	-0.004	0.010	EPSD	TCGA;ICGC;COSMIC	0.010	Gain
Other_Aur_AurB_ST	Q09666	AHNAK	Q96GD4	AURKB	S5860	S5864P	5864	Missense	distal	4	no	0.013	0.012	EPSD	TCGA;ICGC;COSMIC	0.010	Down-regulation
Other_Aur_AurB_ST	O76021	RSL1D1	Q96GD4	AURKB	S278	R277I	277	Missense	proximal	-1	no	0.017	0.010	EPSD	TCGA;ICGC;COSMIC	0.010	Down-regulation
Other_Aur_AurB_ST	O76021	RSL1D1	Q96GD4	AURKB	T375	K373R	373	Missense	proximal	-2	no	0.010	0.069	EPSD	TCGA;ICGC;COSMIC	0.010	Up-regulation
Other_Aur_AurB_ST	O76021	RSL1D1	Q96GD4	AURKB	T454	A451V	451	Missense	distal	-3	no	0.070	0.069	EPSD	TCGA;ICGC;COSMIC;GDSC;CCLE	0.010	Down-regulation
Other_Aur_AurB_ST	O76021	RSL1D1	Q96GD4	AURKB	S474	S474P	474	Missense	central	0	yes	0.019	0.000	EPSD	TCGA;ICGC;COSMIC	0.010	Loss
AGC_RSK_RSKp90_RPS6KA2_ST	P16220	CREB1	Q15349	RPS6KA2	S98	S103A	103	Missense	distal	5	no	12.951	12.851	EPSD	TCGA;COSMIC	8.741	Down-regulation
AGC_RSK_RSKp90_RPS6KA2_ST	P16220	CREB1	Q15349	RPS6KA2	S133	L128I	128	Missense	distal	-5	no	13.505	12.659	PhosphoSitePlus	TCGA;COSMIC	8.741	Down-regulation
TK_Src_SrcB_BLK_Y	P12318	FCGR2A	P51451	BLK	Y281	E282A	282	Missense	proximal	1	no	2.051	2.039	EPSD	TCGA;ICGC;COSMIC	0.806	Down-regulation
TK_Src_SrcB_BLK_Y	P12318	FCGR2A	P51451	BLK	Y281	D280E	280	Missense	proximal	-1	no	2.051	2.010	EPSD	TCGA;ICGC;COSMIC	0.806	Down-regulation
TK_Src_SrcB_BLK_Y	P12318	FCGR2A	P51451	BLK	Y281	T283A	283	Missense	proximal	2	no	2.051	2.018	EPSD	TCGA;ICGC;COSMIC	0.806	Down-regulation
TK_Src_SrcB_BLK_Y	P12318	FCGR2A	P51451	BLK	Y281	G287S	287	Missense	distal	6	no	2.051	2.018	EPSD	TCGA;ICGC;COSMIC	0.806	Down-regulation
TK_Src_SrcB_BLK_Y	P12318	FCGR2A	P51451	BLK	Y288	E282A	282	Missense	distal	-6	no	2.162	2.097	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	0.806	Down-regulation
TK_Src_SrcB_BLK_Y	P12318	FCGR2A	P51451	BLK	Y288	T283A	283	Missense	distal	-5	no	2.162	1.690	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	0.806	Down-regulation
TK_Src_SrcB_BLK_Y	P12318	FCGR2A	P51451	BLK	Y288	G287S	287	Missense	proximal	-1	no	2.162	2.154	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	0.806	Down-regulation
TK_Src_SrcB_BLK_Y	P12318	FCGR2A	P51451	BLK	Y304	I303M	303	Missense	proximal	-1	no	1.972	1.968	PhosphoSitePlus;EPSD	TCGA;ICGC;COSMIC	0.806	Down-regulation
TK_Src_SrcB_BLK_Y	P12318	FCGR2A	P51451	BLK	Y304	D311H	311	Missense	distal	7	no	1.972	1.857	PhosphoSitePlus;EPSD	TCGA;ICGC;COSMIC	0.806	Down-regulation
TK_Src_SrcB_BLK_Y	P12318	FCGR2A	P51451	BLK	Y304	K301I	301	Missense	distal	-3	no	1.972	1.917	PhosphoSitePlus;EPSD	TCGA;ICGC;COSMIC	0.806	Down-regulation
TK_Src_SrcB_BLK_Y	P12318	FCGR2A	P51451	BLK	Y304	P308S	308	Missense	distal	4	no	1.972	1.865	PhosphoSitePlus;EPSD	TCGA;ICGC;COSMIC	0.806	Down-regulation
TK_Src_SrcB_BLK_Y	P12318	FCGR2A	P51451	BLK	Y304	D299Y	299	Missense	distal	-5	no	1.972	1.168	PhosphoSitePlus;EPSD	TCGA	0.806	Down-regulation
TK_Src_SrcB_BLK_Y	P31994	FCGR2B	P51451	BLK	Y292	L295I	295	Missense	distal	3	no	2.045	1.820	PhosphoSitePlus	TCGA;ICGC	0.806	Down-regulation
Other_NEK_NEK2_NEK2_ST	Q8N137	CNTROB	P51955	NEK2	S45	A52T	52	Missense	distal	7	no	3.154	3.141	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC;CCLE	1.575	Down-regulation
Other_NEK_NEK2_NEK2_ST	Q8N137	CNTROB	P51955	NEK2	T570	N565S	565	Missense	distal	-5	no	1.684	1.640	EPSD	TCGA;ICGC;COSMIC	1.575	Down-regulation
Other_NEK_NEK2_NEK2_ST	Q8N137	CNTROB	P51955	NEK2	T571	N565S	565	Missense	distal	-6	no	1.685	1.686	EPSD	TCGA;ICGC;COSMIC	1.575	Up-regulation
Other_NEK_NEK2_NEK2_ST	Q8N137	CNTROB	P51955	NEK2	S769	L770I	770	Missense	proximal	1	no	1.748	1.756	EPSD	TCGA;ICGC;COSMIC	1.575	Up-regulation
Other_NEK_NEK2_NEK2_ST	P51955	NEK2	P51955	NEK2	T170	T170M	170	Missense	central	0	yes	2.885	0.000	EPSD;PhosphoSitePlus	TCGA	1.575	Loss
Other_NEK_NEK2_NEK2_ST	P51955	NEK2	P51955	NEK2	T170	A163D	163	Missense	distal	-7	no	2.885	2.767	EPSD;PhosphoSitePlus	TCGA;COSMIC	1.575	Down-regulation
Other_NEK_NEK2_NEK2_ST	P51955	NEK2	P51955	NEK2	S171	T170M	170	Missense	proximal	-1	no	3.034	2.447	EPSD;PhosphoSitePlus	TCGA	1.575	Down-regulation
Other_NEK_NEK2_NEK2_ST	P51955	NEK2	P51955	NEK2	T175	T170M	170	Missense	distal	-5	no	3.241	3.200	EPSD;PhosphoSitePlus	TCGA	1.575	Down-regulation
Other_NEK_NEK2_NEK2_ST	P51955	NEK2	P51955	NEK2	T179	P185L	185	Missense	distal	6	no	3.148	3.121	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	1.575	Down-regulation
Other_NEK_NEK2_NEK2_ST	P51955	NEK2	P51955	NEK2	S241	P237S	237	Missense	distal	-4	no	3.396	3.357	PhosphoSitePlus;EPSD	TCGA;ICGC;COSMIC	1.575	Down-regulation
Other_NEK_NEK2_NEK2_ST	P51955	NEK2	P51955	NEK2	S241	R235Q	235	Missense	distal	-6	no	3.396	3.395	PhosphoSitePlus;EPSD	TCGA;ICGC;COSMIC	1.575	Down-regulation
Other_NEK_NEK2_NEK2_ST	P51955	NEK2	P51955	NEK2	S356	E360K	360	Missense	distal	4	no	2.945	3.037	EPSD;PhosphoSitePlus	TCGA;ICGC	1.575	Up-regulation
Other_NEK_NEK2_NEK2_ST	P51955	NEK2	P51955	NEK2	S356	L351M	351	Missense	distal	-5	no	2.945	2.908	EPSD;PhosphoSitePlus	TCGA;COSMIC	1.575	Down-regulation
Other_NEK_NEK2_NEK2_ST	P51955	NEK2	P51955	NEK2	S397	S402G	402	Missense	distal	5	no	3.078	2.990	EPSD;PhosphoSitePlus	TCGA;COSMIC	1.575	Down-regulation
Other_NEK_NEK2_NEK2_ST	P51955	NEK2	P51955	NEK2	S402	S402G	402	Missense	central	0	yes	3.147	0.000	EPSD;PhosphoSitePlus	TCGA;COSMIC	1.575	Loss
Other_NEK_NEK2_NEK2_ST	P51955	NEK2	P51955	NEK2	S402	S408P	408	Missense	distal	6	no	3.147	3.224	EPSD;PhosphoSitePlus	TCGA	1.575	Up-regulation
Other_NEK_NEK2_NEK2_ST	P51955	NEK2	P51955	NEK2	T405	S402G	402	Missense	distal	-3	no	1.530	1.668	EPSD	TCGA;COSMIC	1.575	Gain
Other_NEK_NEK2_NEK2_ST	P51955	NEK2	P51955	NEK2	S428	N433K	433	Missense	distal	5	no	1.977	2.084	EPSD;PhosphoSitePlus	TCGA;COSMIC	1.575	Up-regulation
Other_NEK_NEK2_NEK2_ST	P51955	NEK2	P51955	NEK2	S428	R423Q	423	Missense	distal	-5	no	1.977	1.957	EPSD;PhosphoSitePlus	TCGA;COSMIC	1.575	Down-regulation
Other_NEK_NEK2_NEK2_ST	P36873	PPP1CC	P51955	NEK2	T307	K301T	301	Missense	distal	-6	no	2.056	2.055	PhosphoSitePlus;EPSD	TCGA;COSMIC	1.575	Down-regulation
Other_NEK_NEK2_NEK2_ST	P36873	PPP1CC	P51955	NEK2	T307	A306D	306	Missense	proximal	-1	no	2.056	2.144	PhosphoSitePlus;EPSD	TCGA;COSMIC	1.575	Up-regulation
Other_NEK_NEK2_NEK2_ST	P36873	PPP1CC	P51955	NEK2	T307	R314M	314	Missense	distal	7	no	2.056	2.220	PhosphoSitePlus;EPSD	TCGA;ICGC;COSMIC	1.575	Up-regulation
Other_NEK_NEK2_NEK2_ST	P36873	PPP1CC	P51955	NEK2	T307	T307M	307	Missense	central	0	yes	2.056	0.000	PhosphoSitePlus;EPSD	TCGA;COSMIC	1.575	Loss
Other_NEK_NEK2_NEK2_ST	P36873	PPP1CC	P51955	NEK2	T318	R314M	314	Missense	distal	-4	no	1.930	2.013	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	1.575	Up-regulation
Other_NEK_NEK2_NEK2_ST	Q9H2D6	TRIOBP	P51955	NEK2	T285	H282Y	282	Missense	distal	-3	no	1.344	1.653	EPSD	TCGA;ICGC;COSMIC	1.575	Gain
Other_NEK_NEK2_NEK2_ST	Q9H2D6	TRIOBP	P51955	NEK2	T594	T600A	600	Missense	distal	6	no	2.002	1.865	EPSD	TCGA;ICGC;COSMIC	1.575	Down-regulation
Other_NEK_NEK2_NEK2_ST	Q9H2D6	TRIOBP	P51955	NEK2	T594	P598S	598	Missense	distal	4	no	2.002	2.035	EPSD	TCGA;ICGC;COSMIC	1.575	Up-regulation
Other_NEK_NEK2_NEK2_ST	Q9H2D6	TRIOBP	P51955	NEK2	T594	S589F	589	Missense	distal	-5	no	2.002	2.024	EPSD	TCGA;ICGC;COSMIC	1.575	Up-regulation
Other_NEK_NEK2_NEK2_ST	Q9H2D6	TRIOBP	P51955	NEK2	T594	P590L	590	Missense	distal	-4	no	2.002	1.940	EPSD	TCGA;ICGC;COSMIC	1.575	Down-regulation
Other_NEK_NEK2_NEK2_ST	Q9H2D6	TRIOBP	P51955	NEK2	T714	S710F	710	Missense	distal	-4	no	1.575	1.420	EPSD	TCGA	1.575	Loss
Other_NEK_NEK2_NEK2_ST	Q9H2D6	TRIOBP	P51955	NEK2	T714	S710A	710	Missense	distal	-4	no	1.575	1.471	EPSD	TCGA;ICGC;COSMIC	1.575	Loss
Other_NEK_NEK2_NEK2_ST	Q9H2D6	TRIOBP	P51955	NEK2	T714	S709P	709	Missense	distal	-5	no	1.575	1.624	EPSD	TCGA;ICGC;COSMIC	1.575	Up-regulation
Other_NEK_NEK2_NEK2_ST	Q9H2D6	TRIOBP	P51955	NEK2	T715	S710F	710	Missense	distal	-5	no	1.934	1.955	EPSD	TCGA	1.575	Up-regulation
Other_NEK_NEK2_NEK2_ST	Q9H2D6	TRIOBP	P51955	NEK2	T715	S710A	710	Missense	distal	-5	no	1.934	1.944	EPSD	TCGA;ICGC;COSMIC	1.575	Up-regulation
Other_NEK_NEK2_NEK2_ST	Q9H2D6	TRIOBP	P51955	NEK2	T715	S709P	709	Missense	distal	-6	no	1.934	1.933	EPSD	TCGA;ICGC;COSMIC	1.575	Down-regulation
Other_NEK_NEK2_NEK2_ST	Q9H2D6	TRIOBP	P51955	NEK2	S757	R751Q	751	Missense	distal	-6	no	1.652	1.651	EPSD	TCGA;ICGC;COSMIC	1.575	Down-regulation
Other_NEK_NEK2_NEK2_ST	Q9H2D6	TRIOBP	P51955	NEK2	S757	Q764K	764	Missense	distal	7	no	1.652	1.717	EPSD	TCGA;ICGC;COSMIC	1.575	Up-regulation
Other_NEK_NEK2_NEK2_ST	Q9H2D6	TRIOBP	P51955	NEK2	S757	Q750P	750	Missense	distal	-7	no	1.652	1.380	EPSD	TCGA;ICGC;COSMIC	1.575	Loss
Other_NEK_NEK2_NEK2_ST	Q9H2D6	TRIOBP	P51955	NEK2	S757	S757F	757	Missense	central	0	yes	1.652	0.000	EPSD	TCGA;ICGC;COSMIC	1.575	Loss
Other_NEK_NEK2_NEK2_ST	Q9H2D6	TRIOBP	P51955	NEK2	S757	S757Y	757	Missense	central	0	yes	1.652	0.000	EPSD	TCGA;ICGC;COSMIC	1.575	Loss
Other_NEK_NEK2_NEK2_ST	Q9H2D6	TRIOBP	P51955	NEK2	T817	R816I	816	Missense	proximal	-1	no	2.398	2.110	EPSD	TCGA;ICGC	1.575	Down-regulation
Other_NEK_NEK2_NEK2_ST	Q9H2D6	TRIOBP	P51955	NEK2	T817	P824S	824	Missense	distal	7	no	2.398	2.404	EPSD	TCGA;ICGC;COSMIC	1.575	Up-regulation
Other_NEK_NEK2_NEK2_ST	Q9H2D6	TRIOBP	P51955	NEK2	T817	R816G	816	Missense	proximal	-1	no	2.398	2.478	EPSD	TCGA;ICGC	1.575	Up-regulation
Other_NEK_NEK2_NEK2_ST	Q9H2D6	TRIOBP	P51955	NEK2	S895	R899C	899	Missense	distal	4	no	1.687	1.588	EPSD	TCGA;ICGC;COSMIC	1.575	Down-regulation
Other_NEK_NEK2_NEK2_ST	Q9H2D6	TRIOBP	P51955	NEK2	S895	N901Y	901	Missense	distal	6	no	1.687	1.715	EPSD	TCGA;ICGC;COSMIC	1.575	Up-regulation
Other_NEK_NEK2_NEK2_ST	Q9H2D6	TRIOBP	P51955	NEK2	S895	P897S	897	Missense	proximal	2	no	1.687	1.616	EPSD	TCGA;ICGC;COSMIC	1.575	Down-regulation
Other_NEK_NEK2_NEK2_ST	Q9H2D6	TRIOBP	P51955	NEK2	S895	S895L	895	Missense	central	0	yes	1.687	0.000	EPSD	TCGA;ICGC;COSMIC	1.575	Loss
Other_NEK_NEK2_NEK2_ST	Q9H2D6	TRIOBP	P51955	NEK2	S895	P892L	892	Missense	distal	-3	no	1.687	2.513	EPSD	TCGA;ICGC;COSMIC	1.575	Up-regulation
Other_NEK_NEK2_NEK2_ST	Q9H2D6	TRIOBP	P51955	NEK2	S923	S922C	922	Missense	proximal	-1	no	2.266	2.388	EPSD	TCGA;ICGC;COSMIC	1.575	Up-regulation
Other_NEK_NEK2_NEK2_ST	Q9H2D6	TRIOBP	P51955	NEK2	S923	Q929E	929	Missense	distal	6	no	2.266	2.011	EPSD	TCGA;ICGC;COSMIC	1.575	Down-regulation
Other_NEK_NEK2_NEK2_ST	Q9H2D6	TRIOBP	P51955	NEK2	S1243	P1244H	1244	Missense	proximal	1	no	1.670	1.628	EPSD	TCGA;ICGC;COSMIC	1.575	Down-regulation
Other_NEK_NEK2_NEK2_ST	Q9H2D6	TRIOBP	P51955	NEK2	S1243	G1250E	1250	Missense	distal	7	no	1.670	1.712	EPSD	TCGA;ICGC;COSMIC	1.575	Up-regulation
Other_NEK_NEK2_NEK2_ST	Q9H2D6	TRIOBP	P51955	NEK2	T1684	E1682K	1682	Missense	proximal	-2	no	2.990	2.855	EPSD	TCGA;ICGC;COSMIC	1.575	Down-regulation
Other_NEK_NEK2_NEK2_ST	Q9H2D6	TRIOBP	P51955	NEK2	T1684	T1684M	1684	Missense	central	0	yes	2.990	0.000	EPSD	TCGA;ICGC;COSMIC;GDSC	1.575	Loss
Other_NEK_NEK2_NEK2_ST	Q9H2D6	TRIOBP	P51955	NEK2	S1691	T1684M	1684	Missense	distal	-7	no	1.379	1.629	EPSD	TCGA;ICGC;COSMIC;GDSC	1.575	Gain
Other_NEK_NEK2_NEK2_ST	Q9H2D6	TRIOBP	P51955	NEK2	T1961	R1958Q	1958	Missense	distal	-3	no	1.633	2.043	EPSD	TCGA;ICGC;COSMIC	1.575	Up-regulation
Other_NEK_NEK2_NEK2_ST	Q9H2D6	TRIOBP	P51955	NEK2	T1961	R1968C	1968	Missense	distal	7	no	1.633	1.674	EPSD	TCGA;ICGC;COSMIC	1.575	Up-regulation
Other_NEK_NEK2_NEK2_ST	Q9H2D6	TRIOBP	P51955	NEK2	T1961	R1964C	1964	Missense	distal	3	no	1.633	1.719	EPSD	TCGA;ICGC;COSMIC;CCLE	1.575	Up-regulation
Other_NEK_NEK2_NEK2_ST	Q9H2D6	TRIOBP	P51955	NEK2	T1961	R1960H	1960	Missense	proximal	-1	no	1.633	1.175	EPSD	TCGA;ICGC;COSMIC;CCLE	1.575	Loss
Other_NEK_NEK2_NEK2_ST	Q92997	DVL3	P51955	NEK2	T15	V19M	19	Missense	distal	4	no	2.112	2.319	PhosphoSitePlus;EPSD	TCGA;ICGC;COSMIC	1.575	Up-regulation
Other_NEK_NEK2_NEK2_ST	Q92997	DVL3	P51955	NEK2	T15	L18F	18	Missense	distal	3	no	2.112	2.040	PhosphoSitePlus;EPSD	TCGA;ICGC;COSMIC	1.575	Down-regulation
Other_NEK_NEK2_NEK2_ST	Q92997	DVL3	P51955	NEK2	S48	F44L	44	Missense	distal	-4	no	1.543	1.674	EPSD	TCGA;ICGC;COSMIC	1.575	Gain
Other_NEK_NEK2_NEK2_ST	Q92997	DVL3	P51955	NEK2	S280	D273Y	273	Missense	distal	-7	no	2.946	2.947	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	1.575	Up-regulation
Other_NEK_NEK2_NEK2_ST	Q92997	DVL3	P51955	NEK2	S280	M282T	282	Missense	proximal	2	no	2.946	3.067	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	1.575	Up-regulation
Other_NEK_NEK2_NEK2_ST	Q92997	DVL3	P51955	NEK2	S280	M282R	282	Missense	proximal	2	no	2.946	3.097	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	1.575	Up-regulation
Other_NEK_NEK2_NEK2_ST	Q92997	DVL3	P51955	NEK2	S280	I281V	281	Missense	proximal	1	no	2.946	2.997	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	1.575	Up-regulation
Other_NEK_NEK2_NEK2_ST	Q92997	DVL3	P51955	NEK2	S578	G582S	582	Missense	distal	4	no	1.484	1.683	EPSD	TCGA;COSMIC	1.575	Gain
Other_NEK_NEK2_NEK2_ST	Q92997	DVL3	P51955	NEK2	S643	R645C	645	Missense	proximal	2	no	2.943	2.911	EPSD;PhosphoSitePlus	TCGA;COSMIC	1.575	Down-regulation
Other_NEK_NEK2_NEK2_ST	Q92997	DVL3	P51955	NEK2	T695	P692L	692	Missense	distal	-3	no	0.915	1.741	EPSD	TCGA;ICGC;COSMIC	1.575	Gain
Other_NEK_NEK2_NEK2_ST	Q92997	DVL3	P51955	NEK2	S697	E693K	693	Missense	distal	-4	no	1.985	1.884	EPSD;PhosphoSitePlus	TCGA;COSMIC	1.575	Down-regulation
Other_NEK_NEK2_NEK2_ST	Q92997	DVL3	P51955	NEK2	S697	P692L	692	Missense	distal	-5	no	1.985	1.973	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	1.575	Down-regulation
Other_NEK_NEK2_NEK2_ST	P54274	TERF1	P51955	NEK2	S160	E164Q	164	Missense	distal	4	no	2.941	2.539	EPSD	TCGA;ICGC;COSMIC	1.575	Down-regulation
Other_NEK_NEK2_NEK2_ST	P54274	TERF1	P51955	NEK2	S160	G159A	159	Missense	proximal	-1	no	2.941	2.524	EPSD	TCGA;ICGC;COSMIC	1.575	Down-regulation
Other_NEK_NEK2_NEK2_ST	Q9BV73	CEP250	P51955	NEK2	S1927	W1928C	1928	Missense	proximal	1	no	1.960	1.948	EPSD	TCGA;COSMIC	1.575	Down-regulation
Other_NEK_NEK2_NEK2_ST	Q9BV73	CEP250	P51955	NEK2	S1927	R1922K	1922	Missense	distal	-5	no	1.960	1.845	EPSD	TCGA;COSMIC	1.575	Down-regulation
Other_NEK_NEK2_NEK2_ST	Q9BV73	CEP250	P51955	NEK2	S1927	A1933T	1933	Missense	distal	6	no	1.960	2.097	EPSD	TCGA;COSMIC	1.575	Up-regulation
Other_NEK_NEK2_NEK2_ST	Q9BV73	CEP250	P51955	NEK2	T2218	E2223D	2223	Missense	distal	5	no	1.717	1.548	EPSD	TCGA	1.575	Loss
Other_NEK_NEK2_NEK2_ST	Q9BV73	CEP250	P51955	NEK2	S2417	S2421N	2421	Missense	distal	4	no	2.004	1.993	PhosphoSitePlus;EPSD	TCGA	1.575	Down-regulation
Other_NEK_NEK2_NEK2_ST	Q9BV73	CEP250	P51955	NEK2	S2421	G2426V	2426	Missense	distal	5	no	2.251	2.230	EPSD;PhosphoSitePlus	TCGA;COSMIC	1.575	Down-regulation
Other_NEK_NEK2_NEK2_ST	Q9BV73	CEP250	P51955	NEK2	S2421	S2421N	2421	Missense	central	0	yes	2.251	0.000	EPSD;PhosphoSitePlus	TCGA	1.575	Loss
Other_NEK_NEK2_NEK2_ST	P06748	NPM1	P51955	NEK2	T46	S43Y	43	Missense	distal	-3	no	0.705	1.710	EPSD	TCGA;ICGC;COSMIC	1.575	Gain
Other_NEK_NEK2_NEK2_ST	P06748	NPM1	P51955	NEK2	S70	K73Q	73	Missense	distal	3	no	3.055	2.903	PhosphoSitePlus;EPSD	TCGA;ICGC;COSMIC	1.575	Down-regulation
Other_NEK_NEK2_NEK2_ST	P06748	NPM1	P51955	NEK2	S88	E93K	93	Missense	distal	5	no	3.227	3.347	EPSD;PhosphoSitePlus	TCGA;ICGC	1.575	Up-regulation
Other_NEK_NEK2_NEK2_ST	P06748	NPM1	P51955	NEK2	S139	L136F	136	Missense	distal	-3	no	1.497	1.930	EPSD	TCGA;ICGC;COSMIC	1.575	Gain
Other_NEK_NEK2_NEK2_ST	P06748	NPM1	P51955	NEK2	S143	L136F	136	Missense	distal	-7	no	1.686	1.733	EPSD	TCGA;ICGC;COSMIC	1.575	Up-regulation
Other_NEK_NEK2_NEK2_ST	P06748	NPM1	P51955	NEK2	S143	I138V	138	Missense	distal	-5	no	1.686	1.679	EPSD	TCGA;ICGC;COSMIC;GDSC;CCLE	1.575	Down-regulation
Other_NEK_NEK2_NEK2_ST	P06748	NPM1	P51955	NEK2	S143	G147D	147	Missense	distal	4	no	1.686	1.593	EPSD	TCGA;ICGC;COSMIC	1.575	Down-regulation
Other_NEK_NEK2_NEK2_ST	P06748	NPM1	P51955	NEK2	S260	K257E	257	Missense	distal	-3	no	1.629	1.015	EPSD	TCGA;ICGC;COSMIC	1.575	Loss
Other_NEK_NEK2_NEK2_ST	P06748	NPM1	P51955	NEK2	S260	A266T	266	Missense	distal	6	no	1.629	1.766	EPSD	TCGA;ICGC	1.575	Up-regulation
Other_NEK_NEK2_NEK2_ST	P13639	EEF2	P51955	NEK2	T59	E63K	63	Missense	distal	4	no	2.168	2.261	EPSD	TCGA;ICGC;COSMIC	1.575	Up-regulation
Other_NEK_NEK2_NEK2_ST	P13639	EEF2	P51955	NEK2	T59	T54S	54	Missense	distal	-5	no	2.168	2.126	EPSD	TCGA;ICGC;COSMIC	1.575	Down-regulation
Other_NEK_NEK2_NEK2_ST	P13639	EEF2	P51955	NEK2	T59	T57I	57	Missense	proximal	-2	no	2.168	1.984	EPSD	TCGA;ICGC;COSMIC	1.575	Down-regulation
Other_NEK_NEK2_NEK2_ST	P13639	EEF2	P51955	NEK2	S279	S276L	276	Missense	distal	-3	no	1.616	2.257	EPSD	TCGA;ICGC;COSMIC	1.575	Up-regulation
Other_NEK_NEK2_NEK2_ST	P13639	EEF2	P51955	NEK2	S279	S274G	274	Missense	distal	-5	no	1.616	1.688	EPSD	TCGA;ICGC;COSMIC	1.575	Up-regulation
Other_NEK_NEK2_NEK2_ST	P13639	EEF2	P51955	NEK2	S279	E281K	281	Missense	proximal	2	no	1.616	1.579	EPSD	TCGA;ICGC	1.575	Down-regulation
Other_NEK_NEK2_NEK2_ST	P13639	EEF2	P51955	NEK2	S360	L358V	358	Missense	proximal	-2	no	1.679	1.853	EPSD	TCGA;ICGC;COSMIC	1.575	Up-regulation
Other_NEK_NEK2_NEK2_ST	P13639	EEF2	P51955	NEK2	T482	D476N	476	Missense	distal	-6	no	1.585	1.584	EPSD	TCGA	1.575	Down-regulation
Other_NEK_NEK2_NEK2_ST	P13639	EEF2	P51955	NEK2	T482	D476V	476	Missense	distal	-6	no	1.585	1.586	EPSD	TCGA;ICGC;COSMIC	1.575	Up-regulation
Other_NEK_NEK2_NEK2_ST	P13639	EEF2	P51955	NEK2	T582	R580C	580	Missense	proximal	-2	no	1.751	1.525	EPSD	TCGA;ICGC;COSMIC	1.575	Loss
Other_NEK_NEK2_NEK2_ST	P13639	EEF2	P51955	NEK2	T582	T582M	582	Missense	central	0	yes	1.751	0.000	EPSD	TCGA;ICGC;COSMIC	1.575	Loss
Other_NEK_NEK2_NEK2_ST	P13639	EEF2	P51955	NEK2	T582	V589M	589	Missense	distal	7	no	1.751	1.867	EPSD	TCGA;ICGC	1.575	Up-regulation
Other_NEK_NEK2_NEK2_ST	P13639	EEF2	P51955	NEK2	S593	L590F	590	Missense	distal	-3	no	1.260	1.693	EPSD	TCGA;ICGC	1.575	Gain
Other_NEK_NEK2_NEK2_ST	P13639	EEF2	P51955	NEK2	S595	R601W	601	Missense	distal	6	no	2.095	2.102	PhosphoSitePlus	TCGA;ICGC;COSMIC	1.575	Up-regulation
Other_NEK_NEK2_NEK2_ST	P13639	EEF2	P51955	NEK2	S595	L590F	590	Missense	distal	-5	no	2.095	2.079	PhosphoSitePlus	TCGA;ICGC	1.575	Down-regulation
Other_NEK_NEK2_NEK2_ST	P13639	EEF2	P51955	NEK2	S595	V589M	589	Missense	distal	-6	no	2.095	2.092	PhosphoSitePlus	TCGA;ICGC	1.575	Down-regulation
Other_NEK_NEK2_NEK2_ST	P13639	EEF2	P51955	NEK2	S732	A736T	736	Missense	distal	4	no	1.725	1.775	EPSD	TCGA;ICGC;COSMIC	1.575	Up-regulation
Other_NEK_NEK2_NEK2_ST	P13639	EEF2	P51955	NEK2	S793	V790I	790	Missense	distal	-3	no	1.634	2.018	EPSD	TCGA;ICGC;COSMIC	1.575	Up-regulation
Other_NEK_NEK2_NEK2_ST	P13639	EEF2	P51955	NEK2	S793	A798T	798	Missense	distal	5	no	1.634	1.606	EPSD	TCGA;ICGC;COSMIC	1.575	Down-regulation
Other_NEK_NEK2_NEK2_ST	O15360	FANCA	P51955	NEK2	T323	F320L	320	Missense	distal	-3	no	1.658	1.226	EPSD	TCGA;ICGC;COSMIC	1.575	Loss
Other_NEK_NEK2_NEK2_ST	O15360	FANCA	P51955	NEK2	T351	A349V	349	Missense	proximal	-2	no	3.148	3.098	PhosphoSitePlus	TCGA;ICGC;COSMIC	1.575	Down-regulation
Other_NEK_NEK2_NEK2_ST	O15360	FANCA	P51955	NEK2	S1217	E1214Q	1214	Missense	distal	-3	no	1.528	1.743	EPSD	TCGA;ICGC;COSMIC	1.575	Gain
Other_NEK_NEK2_NEK2_ST	O15360	FANCA	P51955	NEK2	T1309	E1310K	1310	Missense	proximal	1	no	1.774	1.777	EPSD	TCGA;ICGC;COSMIC	1.575	Up-regulation
Other_NEK_NEK2_NEK2_ST	O15360	FANCA	P51955	NEK2	T1309	E1310Q	1310	Missense	proximal	1	no	1.774	1.762	EPSD	TCGA;ICGC;COSMIC	1.575	Down-regulation
Other_NEK_NEK2_NEK2_ST	O14777	NDC80	P51955	NEK2	S77	E78Q	78	Missense	proximal	1	no	1.618	1.606	EPSD	TCGA;ICGC;COSMIC	1.575	Down-regulation
Other_NEK_NEK2_NEK2_ST	O14777	NDC80	P51955	NEK2	S77	P83Q	83	Missense	distal	6	no	1.618	1.807	EPSD	TCGA;ICGC;COSMIC	1.575	Up-regulation
Other_NEK_NEK2_NEK2_ST	Q96CN5	LRRC45	P51955	NEK2	T328	A329V	329	Missense	proximal	1	no	1.661	1.713	EPSD	TCGA	1.575	Up-regulation
Other_NEK_NEK2_NEK2_ST	Q96CN5	LRRC45	P51955	NEK2	T328	E332K	332	Missense	distal	4	no	1.661	1.753	EPSD	TCGA;ICGC;COSMIC	1.575	Up-regulation
Other_NEK_NEK2_NEK2_ST	Q96CN5	LRRC45	P51955	NEK2	S337	E332K	332	Missense	distal	-5	no	1.801	1.764	EPSD	TCGA;ICGC;COSMIC	1.575	Down-regulation
Other_NEK_NEK2_NEK2_ST	Q96CN5	LRRC45	P51955	NEK2	S337	L336M	336	Missense	proximal	-1	no	1.801	1.181	EPSD	TCGA;ICGC	1.575	Loss
Other_NEK_NEK2_NEK2_ST	Q96CN5	LRRC45	P51955	NEK2	S399	S399N	399	Missense	central	0	yes	1.751	0.000	EPSD	TCGA;ICGC;COSMIC	1.575	Loss
Other_NEK_NEK2_NEK2_ST	P04637	TP53	P51955	NEK2	S46	D48N	48	Missense	proximal	2	no	2.017	1.812	EPSD	TCGA;ICGC;COSMIC;GDSC;CCLE	1.575	Down-regulation
Other_NEK_NEK2_NEK2_ST	P04637	TP53	P51955	NEK2	S106	L111R	111	Missense	distal	5	no	1.544	1.593	EPSD	TCGA;ICGC;COSMIC	1.575	Gain
Other_NEK_NEK2_NEK2_ST	P04637	TP53	P51955	NEK2	S106	L111P	111	Missense	distal	5	no	1.544	1.786	EPSD	TCGA;ICGC;COSMIC	1.575	Gain
Other_NEK_NEK2_NEK2_ST	P04637	TP53	P51955	NEK2	S106	L111Q	111	Missense	distal	5	no	1.544	1.620	EPSD	TCGA;ICGC;COSMIC	1.575	Gain
Other_NEK_NEK2_NEK2_ST	P04637	TP53	P51955	NEK2	S106	Y107D	107	Missense	proximal	1	no	1.544	1.576	EPSD	TCGA;ICGC;COSMIC	1.575	Gain
Other_NEK_NEK2_NEK2_ST	P04637	TP53	P51955	NEK2	T125	K132N	132	Missense	distal	7	no	1.654	1.568	EPSD	TCGA;ICGC;COSMIC;GDSC;CCLE	1.575	Loss
Other_NEK_NEK2_NEK2_ST	P04637	TP53	P51955	NEK2	T125	S121Y	121	Missense	distal	-4	no	1.654	1.552	EPSD	TCGA;ICGC;COSMIC	1.575	Loss
Other_NEK_NEK2_NEK2_ST	P04637	TP53	P51955	NEK2	T125	K132E	132	Missense	distal	7	no	1.654	1.580	EPSD	TCGA;ICGC;COSMIC;GDSC;CCLE	1.575	Down-regulation
Other_NEK_NEK2_NEK2_ST	P04637	TP53	P51955	NEK2	T125	Y126C	126	Missense	proximal	1	no	1.654	1.663	EPSD	TCGA;ICGC;COSMIC;GDSC	1.575	Up-regulation
Other_NEK_NEK2_NEK2_ST	P04637	TP53	P51955	NEK2	T125	S127P	127	Missense	proximal	2	no	1.654	1.725	EPSD	TCGA;ICGC;COSMIC;GDSC;CCLE	1.575	Up-regulation
Other_NEK_NEK2_NEK2_ST	P04637	TP53	P51955	NEK2	T125	Y126N	126	Missense	proximal	1	no	1.654	1.611	EPSD	TCGA;ICGC;COSMIC	1.575	Down-regulation
Other_NEK_NEK2_NEK2_ST	P04637	TP53	P51955	NEK2	T125	L130V	130	Missense	distal	5	no	1.654	1.674	EPSD	TCGA;ICGC;COSMIC;GDSC;CCLE	1.575	Up-regulation
Other_NEK_NEK2_NEK2_ST	P04637	TP53	P51955	NEK2	T125	K132T	132	Missense	distal	7	no	1.654	1.636	EPSD	TCGA;ICGC;COSMIC;GDSC;CCLE	1.575	Down-regulation
Other_NEK_NEK2_NEK2_ST	P04637	TP53	P51955	NEK2	T125	S127Y	127	Missense	proximal	2	no	1.654	1.729	EPSD	TCGA;ICGC;COSMIC	1.575	Up-regulation
Other_NEK_NEK2_NEK2_ST	P04637	TP53	P51955	NEK2	T125	S127T	127	Missense	proximal	2	no	1.654	1.681	EPSD	TCGA;ICGC;COSMIC	1.575	Up-regulation
Other_NEK_NEK2_NEK2_ST	P04637	TP53	P51955	NEK2	T125	S127F	127	Missense	proximal	2	no	1.654	1.602	EPSD	TCGA;ICGC;COSMIC;CCLE	1.575	Down-regulation
Other_NEK_NEK2_NEK2_ST	P04637	TP53	P51955	NEK2	T125	K132R	132	Missense	distal	7	no	1.654	1.542	EPSD	TCGA;ICGC;COSMIC;GDSC;CCLE	1.575	Loss
Other_NEK_NEK2_NEK2_ST	P04637	TP53	P51955	NEK2	T125	Y126S	126	Missense	proximal	1	no	1.654	1.612	EPSD	TCGA;ICGC;COSMIC	1.575	Down-regulation
Other_NEK_NEK2_NEK2_ST	P04637	TP53	P51955	NEK2	T125	L130P	130	Missense	distal	5	no	1.654	1.896	EPSD	TCGA;ICGC;COSMIC	1.575	Up-regulation
Other_NEK_NEK2_NEK2_ST	P04637	TP53	P51955	NEK2	T125	L130F	130	Missense	distal	5	no	1.654	1.760	EPSD	TCGA;ICGC;COSMIC;CCLE	1.575	Up-regulation
Other_NEK_NEK2_NEK2_ST	P04637	TP53	P51955	NEK2	T125	T125M	125	Missense	central	0	yes	1.654	0.000	EPSD	TCGA;ICGC;COSMIC;GDSC	1.575	Loss
Other_NEK_NEK2_NEK2_ST	P04637	TP53	P51955	NEK2	T125	Y126D	126	Missense	proximal	1	no	1.654	1.686	EPSD	TCGA;ICGC;COSMIC;GDSC	1.575	Up-regulation
Other_NEK_NEK2_NEK2_ST	P04637	TP53	P51955	NEK2	T125	K120E	120	Missense	distal	-5	no	1.654	1.691	EPSD	TCGA;ICGC;COSMIC	1.575	Up-regulation
Other_NEK_NEK2_NEK2_ST	P04637	TP53	P51955	NEK2	T125	N131S	131	Missense	distal	6	no	1.654	1.580	EPSD	TCGA;ICGC;COSMIC	1.575	Down-regulation
Other_NEK_NEK2_NEK2_ST	P04637	TP53	P51955	NEK2	T125	T125P	125	Missense	central	0	yes	1.654	0.000	EPSD	TCGA;ICGC;COSMIC;CCLE	1.575	Loss
Other_NEK_NEK2_NEK2_ST	P04637	TP53	P51955	NEK2	T125	S127C	127	Missense	proximal	2	no	1.654	1.679	EPSD	TCGA;ICGC;COSMIC;CCLE	1.575	Up-regulation
Other_NEK_NEK2_NEK2_ST	P04637	TP53	P51955	NEK2	T125	N131I	131	Missense	distal	6	no	1.654	1.769	EPSD	TCGA;ICGC;COSMIC	1.575	Up-regulation
Other_NEK_NEK2_NEK2_ST	P04637	TP53	P51955	NEK2	T125	Y126H	126	Missense	proximal	1	no	1.654	1.617	EPSD	TCGA;ICGC;COSMIC;GDSC	1.575	Down-regulation
Other_NEK_NEK2_NEK2_ST	P04637	TP53	P51955	NEK2	T125	K132Q	132	Missense	distal	7	no	1.654	1.589	EPSD	TCGA;ICGC;COSMIC;GDSC;CCLE	1.575	Down-regulation
Other_NEK_NEK2_NEK2_ST	P04637	TP53	P51955	NEK2	T125	L130R	130	Missense	distal	5	no	1.654	1.704	EPSD	TCGA;ICGC;COSMIC;CCLE	1.575	Up-regulation
Other_NEK_NEK2_NEK2_ST	P04637	TP53	P51955	NEK2	T155	A159V	159	Missense	distal	4	no	1.836	1.845	EPSD	TCGA;ICGC;COSMIC;GDSC;CCLE	1.575	Up-regulation
Other_NEK_NEK2_NEK2_ST	P04637	TP53	P51955	NEK2	T155	A161T	161	Missense	distal	6	no	1.836	1.973	EPSD	TCGA;ICGC;COSMIC;GDSC;CCLE	1.575	Up-regulation
Other_NEK_NEK2_NEK2_ST	P04637	TP53	P51955	NEK2	T155	P152L	152	Missense	distal	-3	no	1.836	2.662	EPSD	TCGA;ICGC;COSMIC;GDSC;CCLE	1.575	Up-regulation
Other_NEK_NEK2_NEK2_ST	P04637	TP53	P51955	NEK2	T155	D148N	148	Missense	distal	-7	no	1.836	2.304	EPSD	TCGA;ICGC;COSMIC	1.575	Up-regulation
Other_NEK_NEK2_NEK2_ST	P04637	TP53	P51955	NEK2	T155	P151H	151	Missense	distal	-4	no	1.836	1.742	EPSD	TCGA;ICGC;COSMIC;GDSC;CCLE	1.575	Down-regulation
Other_NEK_NEK2_NEK2_ST	P04637	TP53	P51955	NEK2	T155	A161V	161	Missense	distal	6	no	1.836	2.010	EPSD	TCGA;ICGC;COSMIC	1.575	Up-regulation
Other_NEK_NEK2_NEK2_ST	P04637	TP53	P51955	NEK2	T155	A161S	161	Missense	distal	6	no	1.836	1.898	EPSD	TCGA;ICGC;COSMIC	1.575	Up-regulation
Other_NEK_NEK2_NEK2_ST	P04637	TP53	P51955	NEK2	T155	A159P	159	Missense	distal	4	no	1.836	1.759	EPSD	TCGA;ICGC;COSMIC;CCLE	1.575	Down-regulation
Other_NEK_NEK2_NEK2_ST	P04637	TP53	P51955	NEK2	T155	R158H	158	Missense	distal	3	no	1.836	1.980	EPSD	TCGA;ICGC;COSMIC;GDSC;CCLE	1.575	Up-regulation
Other_NEK_NEK2_NEK2_ST	P04637	TP53	P51955	NEK2	T155	P151A	151	Missense	distal	-4	no	1.836	1.694	EPSD	TCGA;ICGC;COSMIC;CCLE	1.575	Down-regulation
Other_NEK_NEK2_NEK2_ST	P04637	TP53	P51955	NEK2	T155	R156P	156	Missense	proximal	1	no	1.836	1.768	EPSD	TCGA;ICGC;COSMIC;GDSC;CCLE	1.575	Down-regulation
Other_NEK_NEK2_NEK2_ST	P04637	TP53	P51955	NEK2	T155	P151S	151	Missense	distal	-4	no	1.836	1.797	EPSD	TCGA;ICGC;COSMIC;GDSC;CCLE	1.575	Down-regulation
Other_NEK_NEK2_NEK2_ST	P04637	TP53	P51955	NEK2	T155	R158G	158	Missense	distal	3	no	1.836	1.933	EPSD	TCGA;ICGC;COSMIC;GDSC;CCLE	1.575	Up-regulation
Other_NEK_NEK2_NEK2_ST	P04637	TP53	P51955	NEK2	T155	V157F	157	Missense	proximal	2	no	1.836	1.658	EPSD	TCGA;ICGC;COSMIC;GDSC;CCLE	1.575	Down-regulation
Other_NEK_NEK2_NEK2_ST	P04637	TP53	P51955	NEK2	T155	V157G	157	Missense	proximal	2	no	1.836	1.791	EPSD	TCGA;ICGC;COSMIC	1.575	Down-regulation
Other_NEK_NEK2_NEK2_ST	P04637	TP53	P51955	NEK2	T155	V157D	157	Missense	proximal	2	no	1.836	1.673	EPSD	TCGA;ICGC;COSMIC	1.575	Down-regulation
Other_NEK_NEK2_NEK2_ST	P04637	TP53	P51955	NEK2	T155	I162N	162	Missense	distal	7	no	1.836	1.867	EPSD	TCGA;ICGC;COSMIC;GDSC;CCLE	1.575	Up-regulation
Other_NEK_NEK2_NEK2_ST	P04637	TP53	P51955	NEK2	T155	T155I	155	Missense	central	0	yes	1.836	0.000	EPSD	TCGA;ICGC;COSMIC;CCLE	1.575	Loss
Other_NEK_NEK2_NEK2_ST	P04637	TP53	P51955	NEK2	T155	R158L	158	Missense	distal	3	no	1.836	2.040	EPSD	TCGA;ICGC;COSMIC;GDSC;CCLE	1.575	Up-regulation
Other_NEK_NEK2_NEK2_ST	P04637	TP53	P51955	NEK2	T155	T155N	155	Missense	central	0	yes	1.836	0.000	EPSD	TCGA;ICGC;COSMIC;GDSC;CCLE	1.575	Loss
Other_NEK_NEK2_NEK2_ST	P04637	TP53	P51955	NEK2	T155	P152S	152	Missense	distal	-3	no	1.836	2.021	EPSD	TCGA;ICGC;COSMIC;CCLE	1.575	Up-regulation
Other_NEK_NEK2_NEK2_ST	P04637	TP53	P51955	NEK2	T155	R156C	156	Missense	proximal	1	no	1.836	1.773	EPSD	TCGA;ICGC;COSMIC	1.575	Down-regulation
Other_NEK_NEK2_NEK2_ST	P04637	TP53	P51955	NEK2	T155	P151T	151	Missense	distal	-4	no	1.836	1.716	EPSD	TCGA;ICGC;COSMIC	1.575	Down-regulation
Other_NEK_NEK2_NEK2_ST	P04637	TP53	P51955	NEK2	T155	T155P	155	Missense	central	0	yes	1.836	0.000	EPSD	TCGA;ICGC;COSMIC;CCLE	1.575	Loss
Other_NEK_NEK2_NEK2_ST	P04637	TP53	P51955	NEK2	T155	R158S	158	Missense	distal	3	no	1.836	1.982	EPSD	TCGA;ICGC;COSMIC	1.575	Up-regulation
Other_NEK_NEK2_NEK2_ST	P04637	TP53	P51955	NEK2	T155	P152Q	152	Missense	distal	-3	no	1.836	1.921	EPSD	TCGA;ICGC;COSMIC	1.575	Up-regulation
Other_NEK_NEK2_NEK2_ST	P04637	TP53	P51955	NEK2	T155	R156H	156	Missense	proximal	1	no	1.836	1.727	EPSD	TCGA;ICGC;COSMIC	1.575	Down-regulation
Other_NEK_NEK2_NEK2_ST	P04637	TP53	P51955	NEK2	T155	R158P	158	Missense	distal	3	no	1.836	2.016	EPSD	TCGA;ICGC;COSMIC;GDSC;CCLE	1.575	Up-regulation
Other_NEK_NEK2_NEK2_ST	P04637	TP53	P51955	NEK2	T155	G154V	154	Missense	proximal	-1	no	1.836	1.355	EPSD	TCGA;ICGC;COSMIC;GDSC;CCLE	1.575	Loss
Other_NEK_NEK2_NEK2_ST	P04637	TP53	P51955	NEK2	T155	V157L	157	Missense	proximal	2	no	1.836	1.682	EPSD	TCGA;ICGC;COSMIC	1.575	Down-regulation
Other_NEK_NEK2_NEK2_ST	P04637	TP53	P51955	NEK2	T155	A161D	161	Missense	distal	6	no	1.836	2.158	EPSD	TCGA;ICGC;COSMIC;GDSC;CCLE	1.575	Up-regulation
Other_NEK_NEK2_NEK2_ST	P04637	TP53	P51955	NEK2	T155	P151R	151	Missense	distal	-4	no	1.836	1.754	EPSD	TCGA;ICGC;COSMIC	1.575	Down-regulation
Other_NEK_NEK2_NEK2_ST	P04637	TP53	P51955	NEK2	T155	M160I	160	Missense	distal	5	no	1.836	1.646	EPSD	TCGA;ICGC;COSMIC	1.575	Down-regulation
Other_NEK_NEK2_NEK2_ST	P04637	TP53	P51955	NEK2	T155	R156G	156	Missense	proximal	1	no	1.836	1.741	EPSD	TCGA;ICGC;COSMIC	1.575	Down-regulation
Other_NEK_NEK2_NEK2_ST	P04637	TP53	P51955	NEK2	T155	A161P	161	Missense	distal	6	no	1.836	1.974	EPSD	TCGA;ICGC;COSMIC	1.575	Up-regulation
Other_NEK_NEK2_NEK2_ST	P04637	TP53	P51955	NEK2	T155	P151L	151	Missense	distal	-4	no	1.836	1.773	EPSD	TCGA;ICGC;COSMIC	1.575	Down-regulation
Other_NEK_NEK2_NEK2_ST	P04637	TP53	P51955	NEK2	T155	I162F	162	Missense	distal	7	no	1.836	1.893	EPSD	TCGA;ICGC;COSMIC	1.575	Up-regulation
Other_NEK_NEK2_NEK2_ST	P04637	TP53	P51955	NEK2	T155	R158C	158	Missense	distal	3	no	1.836	1.922	EPSD	TCGA;ICGC;COSMIC	1.575	Up-regulation
Other_NEK_NEK2_NEK2_ST	P04637	TP53	P51955	NEK2	S215	Y220C	220	Missense	distal	5	no	1.693	1.656	EPSD	TCGA;ICGC;COSMIC;GDSC;CCLE	1.575	Down-regulation
Other_NEK_NEK2_NEK2_ST	P04637	TP53	P51955	NEK2	S215	R213Q	213	Missense	proximal	-2	no	1.693	1.643	EPSD	TCGA;ICGC;COSMIC;GDSC;CCLE	1.575	Down-regulation
Other_NEK_NEK2_NEK2_ST	P04637	TP53	P51955	NEK2	S215	D208N	208	Missense	distal	-7	no	1.693	2.161	EPSD	TCGA;ICGC;COSMIC	1.575	Up-regulation
Other_NEK_NEK2_NEK2_ST	P04637	TP53	P51955	NEK2	S215	H214R	214	Missense	proximal	-1	no	1.693	2.151	EPSD	TCGA;ICGC;COSMIC;GDSC;CCLE	1.575	Up-regulation
Other_NEK_NEK2_NEK2_ST	P04637	TP53	P51955	NEK2	S215	V218E	218	Missense	distal	3	no	1.693	1.673	EPSD	TCGA;ICGC;COSMIC	1.575	Down-regulation
Other_NEK_NEK2_NEK2_ST	P04637	TP53	P51955	NEK2	S215	Y220H	220	Missense	distal	5	no	1.693	1.835	EPSD	TCGA;ICGC;COSMIC	1.575	Up-regulation
Other_NEK_NEK2_NEK2_ST	P04637	TP53	P51955	NEK2	S215	S215I	215	Missense	central	0	yes	1.693	0.000	EPSD	TCGA;ICGC;COSMIC;GDSC;CCLE	1.575	Loss
Other_NEK_NEK2_NEK2_ST	P04637	TP53	P51955	NEK2	S215	V216M	216	Missense	proximal	1	no	1.693	1.654	EPSD	TCGA;ICGC;COSMIC;GDSC;CCLE	1.575	Down-regulation
Other_NEK_NEK2_NEK2_ST	P04637	TP53	P51955	NEK2	S215	Y220S	220	Missense	distal	5	no	1.693	1.759	EPSD	TCGA;ICGC;COSMIC	1.575	Up-regulation
Other_NEK_NEK2_NEK2_ST	P04637	TP53	P51955	NEK2	S215	S215N	215	Missense	central	0	yes	1.693	0.000	EPSD	TCGA;ICGC;COSMIC;GDSC;CCLE	1.575	Loss
Other_NEK_NEK2_NEK2_ST	P04637	TP53	P51955	NEK2	S215	T211I	211	Missense	distal	-4	no	1.693	1.748	EPSD	TCGA;ICGC;COSMIC;CCLE	1.575	Up-regulation
Other_NEK_NEK2_NEK2_ST	P04637	TP53	P51955	NEK2	S215	V216G	216	Missense	proximal	1	no	1.693	1.617	EPSD	TCGA;ICGC;COSMIC	1.575	Down-regulation
Other_NEK_NEK2_NEK2_ST	P04637	TP53	P51955	NEK2	S215	R213L	213	Missense	proximal	-2	no	1.693	1.466	EPSD	TCGA;ICGC;COSMIC;GDSC;CCLE	1.575	Loss
Other_NEK_NEK2_NEK2_ST	P04637	TP53	P51955	NEK2	S215	Y220D	220	Missense	distal	5	no	1.693	1.576	EPSD	TCGA;ICGC;COSMIC;GDSC;CCLE	1.575	Down-regulation
Other_NEK_NEK2_NEK2_ST	P04637	TP53	P51955	NEK2	S215	V216E	216	Missense	proximal	1	no	1.693	1.659	EPSD	TCGA;ICGC;COSMIC	1.575	Down-regulation
Other_NEK_NEK2_NEK2_ST	P04637	TP53	P51955	NEK2	S215	V218G	218	Missense	distal	3	no	1.693	1.663	EPSD	TCGA;ICGC;COSMIC	1.575	Down-regulation
Other_NEK_NEK2_NEK2_ST	P04637	TP53	P51955	NEK2	S215	R213P	213	Missense	proximal	-2	no	1.693	1.469	EPSD	TCGA;ICGC;COSMIC	1.575	Loss
Other_NEK_NEK2_NEK2_ST	P04637	TP53	P51955	NEK2	S215	H214L	214	Missense	proximal	-1	no	1.693	1.894	EPSD	TCGA;ICGC;COSMIC	1.575	Up-regulation
Other_NEK_NEK2_NEK2_ST	P04637	TP53	P51955	NEK2	S215	V216L	216	Missense	proximal	1	no	1.693	1.634	EPSD	TCGA;ICGC;COSMIC;GDSC;CCLE	1.575	Down-regulation
Other_NEK_NEK2_NEK2_ST	P04637	TP53	P51955	NEK2	S215	D208G	208	Missense	distal	-7	no	1.693	1.255	EPSD	TCGA;ICGC;COSMIC	1.575	Loss
Other_NEK_NEK2_NEK2_ST	P04637	TP53	P51955	NEK2	S215	S215G	215	Missense	central	0	yes	1.693	0.000	EPSD	TCGA;ICGC;COSMIC;GDSC;CCLE	1.575	Loss
Other_NEK_NEK2_NEK2_ST	P04637	TP53	P51955	NEK2	S215	R213G	213	Missense	proximal	-2	no	1.693	1.340	EPSD	TCGA;ICGC;COSMIC	1.575	Loss
Other_NEK_NEK2_NEK2_ST	P04637	TP53	P51955	NEK2	S215	S215R	215	Missense	central	0	yes	1.693	0.000	EPSD	TCGA;ICGC;COSMIC;GDSC;CCLE	1.575	Loss
Other_NEK_NEK2_NEK2_ST	P04637	TP53	P51955	NEK2	S215	T211A	211	Missense	distal	-4	no	1.693	1.671	EPSD	TCGA;ICGC;COSMIC;CCLE	1.575	Down-regulation
Other_NEK_NEK2_NEK2_ST	P04637	TP53	P51955	NEK2	S269	G262V	262	Missense	distal	-7	no	1.358	1.805	EPSD	TCGA;ICGC;COSMIC;GDSC;CCLE	1.575	Gain
Other_NEK_NEK2_NEK2_ST	P04637	TP53	P51955	NEK2	T284	D281Y	281	Missense	distal	-3	no	0.174	1.832	EPSD	TCGA;ICGC;COSMIC;GDSC;CCLE	1.575	Gain
CAMK_PIM_PIM1_ST	Q13309	SKP2	P11309	PIM1	S64	L59R	59	Missense	distal	-5	no	0.000	0.001	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	0.001	Gain
CAMK_PIM_PIM1_ST	Q99683	MAP3K5	P11309	PIM1	S613	S613N	613	Missense	central	0	yes	0.001	0.000	EPSD	TCGA;COSMIC	0.001	Loss
CAMK_PIM_PIM1_ST	Q99683	MAP3K5	P11309	PIM1	S615	S615C	615	Missense	central	0	yes	0.001	0.000	EPSD	TCGA;COSMIC	0.001	Loss
CAMK_PIM_PIM1_ST	Q99683	MAP3K5	P11309	PIM1	S966	S966F	966	Missense	central	0	yes	0.001	0.000	EPSD	TCGA;COSMIC;CCLE	0.001	Loss
CAMK_PIM_PIM1_ST	Q99683	MAP3K5	P11309	PIM1	S986	E981K	981	Missense	distal	-5	no	0.000	0.001	EPSD	TCGA;COSMIC	0.001	Gain
CAMK_PIM_PIM1_ST	Q99683	MAP3K5	P11309	PIM1	S1039	E1036K	1036	Missense	distal	-3	no	0.000	0.001	EPSD	TCGA;COSMIC	0.001	Gain
CAMK_PIM_PIM1_ST	Q99683	MAP3K5	P11309	PIM1	T1059	T1059M	1059	Missense	central	0	yes	0.001	0.000	EPSD	TCGA;COSMIC	0.001	Loss
CAMK_PIM_PIM1_ST	Q99683	MAP3K5	P11309	PIM1	S1072	S1072F	1072	Missense	central	0	yes	0.001	0.000	EPSD	TCGA;COSMIC	0.001	Loss
CAMK_PIM_PIM1_ST	Q99683	MAP3K5	P11309	PIM1	T1108	T1108I	1108	Missense	central	0	yes	0.001	0.000	EPSD	TCGA;ICGC	0.001	Loss
CAMK_PIM_PIM1_ST	Q99683	MAP3K5	P11309	PIM1	T1108	R1103Q	1103	Missense	distal	-5	no	0.001	0.000	EPSD	TCGA;ICGC;COSMIC	0.001	Loss
CAMK_PIM_PIM1_ST	Q92934	BAD	P11309	PIM1	S25	S25N	25	Missense	central	0	yes	0.001	0.000	EPSD	TCGA	0.001	Loss
CAMK_PIM_PIM1_ST	Q92934	BAD	P11309	PIM1	S134	R131H	131	Missense	distal	-3	no	0.001	0.000	EPSD	TCGA;ICGC;COSMIC	0.001	Loss
CAMK_PIM_PIM1_ST	Q92934	BAD	P11309	PIM1	S134	S134I	134	Missense	central	0	yes	0.001	0.000	EPSD	TCGA	0.001	Loss
CAMK_PIM_PIM1_ST	Q92934	BAD	P11309	PIM1	S164	S164F	164	Missense	central	0	yes	0.001	0.000	EPSD	TCGA;ICGC;COSMIC;GDSC;CCLE	0.001	Loss
CAMK_PIM_PIM1_ST	P38936	CDKN1A	P11309	PIM1	T97	R94W	94	Missense	distal	-3	no	0.001	0.000	EPSD	TCGA;ICGC;COSMIC	0.001	Loss
CAMK_PIM_PIM1_ST	P38936	CDKN1A	P11309	PIM1	T97	R94P	94	Missense	distal	-3	no	0.001	0.000	EPSD	TCGA;ICGC;COSMIC	0.001	Loss
CAMK_PIM_PIM1_ST	P38936	CDKN1A	P11309	PIM1	S98	R93S	93	Missense	distal	-5	no	0.001	0.000	EPSD	TCGA;ICGC;COSMIC	0.001	Loss
CAMK_PIM_PIM1_ST	P38936	CDKN1A	P11309	PIM1	T145	R142W	142	Missense	distal	-3	no	0.003	0.002	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC;GDSC;CCLE	0.001	Down-regulation
CAMK_PIM_PIM1_ST	P38936	CDKN1A	P11309	PIM1	S160	R155H	155	Missense	distal	-5	no	0.002	0.000	EPSD	TCGA;ICGC;COSMIC;CCLE	0.001	Loss
CAMK_PIM_PIM1_ST	P27448	MARK3	P11309	PIM1	T211	T211M	211	Missense	central	0	yes	0.001	0.000	EPSD	TCGA;ICGC	0.001	Loss
CAMK_PIM_PIM1_ST	P27448	MARK3	P11309	PIM1	S456	S456G	456	Missense	central	0	yes	0.001	0.000	EPSD	TCGA;ICGC;COSMIC	0.001	Loss
CAMK_PIM_PIM1_ST	P27448	MARK3	P11309	PIM1	S458	S458I	458	Missense	central	0	yes	0.001	0.000	EPSD	TCGA;ICGC;COSMIC	0.001	Loss
CAMK_PIM_PIM1_ST	P27448	MARK3	P11309	PIM1	S489	R486C	486	Missense	distal	-3	no	0.001	0.000	EPSD	TCGA;ICGC;COSMIC	0.001	Loss
CAMK_PIM_PIM1_ST	P27448	MARK3	P11309	PIM1	T491	R486C	486	Missense	distal	-5	no	0.002	0.001	EPSD	TCGA;ICGC;COSMIC	0.001	Down-regulation
CAMK_PIM_PIM1_ST	P27448	MARK3	P11309	PIM1	T574	P569L	569	Missense	distal	-5	no	0.000	0.001	EPSD	TCGA;ICGC;COSMIC	0.001	Gain
CAMK_PIM_PIM1_ST	P27448	MARK3	P11309	PIM1	S657	K654N	654	Missense	distal	-3	no	0.001	0.000	EPSD	TCGA;COSMIC	0.001	Loss
CAMK_PIM_PIM1_ST	P27448	MARK3	P11309	PIM1	S724	S724A	724	Missense	central	0	yes	0.001	0.000	EPSD	TCGA	0.001	Loss
CAMK_PIM_PIM1_ST	Q01860	POU5F1	P11309	PIM1	S105	G102R	102	Missense	distal	-3	no	0.000	0.001	EPSD	TCGA;ICGC;COSMIC	0.001	Gain
CAMK_PIM_PIM1_ST	Q01860	POU5F1	P11309	PIM1	S107	G102R	102	Missense	distal	-5	no	0.000	0.001	EPSD	TCGA;ICGC;COSMIC	0.001	Gain
CAMK_PIM_PIM1_ST	Q01860	POU5F1	P11309	PIM1	S193	E188Q	188	Missense	distal	-5	no	0.000	0.001	EPSD	TCGA;ICGC;COSMIC	0.001	Gain
CAMK_PIM_PIM1_ST	P35568	IRS1	P11309	PIM1	S36	S36N	36	Missense	central	0	yes	0.001	0.000	EPSD	TCGA;ICGC;COSMIC	0.001	Loss
CAMK_PIM_PIM1_ST	P35568	IRS1	P11309	PIM1	S36	R33C	33	Missense	distal	-3	no	0.001	0.000	EPSD	TCGA;ICGC;COSMIC	0.001	Loss
CAMK_PIM_PIM1_ST	P35568	IRS1	P11309	PIM1	S268	E263K	263	Missense	distal	-5	no	0.001	0.002	EPSD	TCGA;ICGC;COSMIC	0.001	Up-regulation
CAMK_PIM_PIM1_ST	P35568	IRS1	P11309	PIM1	S272	K269N	269	Missense	distal	-3	no	0.002	0.001	EPSD	TCGA;ICGC;COSMIC	0.001	Down-regulation
CAMK_PIM_PIM1_ST	P35568	IRS1	P11309	PIM1	S274	K269N	269	Missense	distal	-5	no	0.001	0.000	EPSD	TCGA;ICGC;COSMIC	0.001	Loss
CAMK_PIM_PIM1_ST	P35568	IRS1	P11309	PIM1	S323	S323A	323	Missense	central	0	yes	0.001	0.000	EPSD	TCGA;ICGC;COSMIC	0.001	Loss
CAMK_PIM_PIM1_ST	P35568	IRS1	P11309	PIM1	S330	R327H	327	Missense	distal	-3	no	0.002	0.001	EPSD	TCGA;ICGC	0.001	Down-regulation
CAMK_PIM_PIM1_ST	P35568	IRS1	P11309	PIM1	S330	S330N	330	Missense	central	0	yes	0.002	0.000	EPSD	TCGA;ICGC;COSMIC	0.001	Loss
CAMK_PIM_PIM1_ST	P35568	IRS1	P11309	PIM1	S341	R338H	338	Missense	distal	-3	no	0.001	0.000	EPSD	TCGA;ICGC;COSMIC	0.001	Loss
CAMK_PIM_PIM1_ST	P35568	IRS1	P11309	PIM1	S341	R338C	338	Missense	distal	-3	no	0.001	0.000	EPSD	TCGA;ICGC;COSMIC	0.001	Loss
CAMK_PIM_PIM1_ST	P35568	IRS1	P11309	PIM1	S362	R360W	360	Missense	proximal	-2	no	0.001	0.000	EPSD	TCGA;ICGC;CCLE	0.001	Loss
CAMK_PIM_PIM1_ST	P35568	IRS1	P11309	PIM1	T446	R443H	443	Missense	distal	-3	no	0.001	0.000	EPSD	TCGA;ICGC	0.001	Loss
CAMK_PIM_PIM1_ST	P35568	IRS1	P11309	PIM1	T498	T498I	498	Missense	central	0	yes	0.001	0.000	EPSD	TCGA;ICGC;COSMIC	0.001	Loss
CAMK_PIM_PIM1_ST	P35568	IRS1	P11309	PIM1	T525	R520W	520	Missense	distal	-5	no	0.002	0.001	EPSD	TCGA;ICGC;COSMIC	0.001	Down-regulation
CAMK_PIM_PIM1_ST	P35568	IRS1	P11309	PIM1	T525	R520Q	520	Missense	distal	-5	no	0.002	0.001	EPSD	TCGA;ICGC;COSMIC	0.001	Down-regulation
CAMK_PIM_PIM1_ST	P35568	IRS1	P11309	PIM1	S527	R522Q	522	Missense	distal	-5	no	0.002	0.001	EPSD	TCGA;ICGC;COSMIC	0.001	Down-regulation
CAMK_PIM_PIM1_ST	P35568	IRS1	P11309	PIM1	S603	R600C	600	Missense	distal	-3	no	0.001	0.000	EPSD	TCGA;ICGC;COSMIC	0.001	Loss
CAMK_PIM_PIM1_ST	P35568	IRS1	P11309	PIM1	T605	R600C	600	Missense	distal	-5	no	0.001	0.000	EPSD	TCGA;ICGC;COSMIC	0.001	Loss
CAMK_PIM_PIM1_ST	P35568	IRS1	P11309	PIM1	S862	R857W	857	Missense	distal	-5	no	0.001	0.000	EPSD	TCGA;ICGC;COSMIC	0.001	Loss
CAMK_PIM_PIM1_ST	P35568	IRS1	P11309	PIM1	S1084	R1081H	1081	Missense	distal	-3	no	0.001	0.000	EPSD	TCGA;ICGC;COSMIC	0.001	Loss
CAMK_PIM_PIM1_ST	P35568	IRS1	P11309	PIM1	S1223	S1223G	1223	Missense	central	0	yes	0.001	0.000	EPSD	TCGA;ICGC;COSMIC	0.001	Loss
CAMK_PIM_PIM1_ST	O43524	FOXO3	P11309	PIM1	S253	R248Q	248	Missense	distal	-5	no	0.002	0.001	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	0.001	Down-regulation
CAMK_PIM_PIM1_ST	O43524	FOXO3	P11309	PIM1	S253	R250W	250	Missense	distal	-3	no	0.002	0.001	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	0.001	Down-regulation
CAMK_PIM_PIM1_ST	O43524	FOXO3	P11309	PIM1	T313	R310C	310	Missense	distal	-3	no	0.001	0.000	EPSD	TCGA;ICGC;COSMIC	0.001	Loss
CAMK_PIM_PIM1_ST	O43524	FOXO3	P11309	PIM1	S315	R310C	310	Missense	distal	-5	no	0.002	0.001	EPSD	TCGA;ICGC;COSMIC	0.001	Down-regulation
CAMK_PIM_PIM1_ST	O43524	FOXO3	P11309	PIM1	S315	S315F	315	Missense	central	0	yes	0.002	0.000	EPSD	TCGA;ICGC;COSMIC	0.001	Loss
CAMK_PIM_PIM1_ST	O43524	FOXO3	P11309	PIM1	S315	R312C	312	Missense	distal	-3	no	0.002	0.001	EPSD	TCGA;ICGC;COSMIC	0.001	Down-regulation
CAMK_PIM_PIM1_ST	O43524	FOXO3	P11309	PIM1	S412	S412C	412	Missense	central	0	yes	0.001	0.000	EPSD	TCGA;ICGC;COSMIC	0.001	Loss
CAMK_PIM_PIM1_ST	O43524	FOXO3	P11309	PIM1	S439	G436R	436	Missense	distal	-3	no	0.000	0.001	EPSD	TCGA;ICGC;COSMIC;GDSC;CCLE	0.001	Gain
CAMK_PIM_PIM1_ST	O43524	FOXO3	P11309	PIM1	S553	S553Y	553	Missense	central	0	yes	0.001	0.000	EPSD	TCGA;ICGC;COSMIC	0.001	Loss
CAMK_PIM_PIM1_ST	P29474	NOS3	P11309	PIM1	S102	R97K	97	Missense	distal	-5	no	0.002	0.001	EPSD	TCGA;ICGC;COSMIC	0.001	Down-regulation
CAMK_PIM_PIM1_ST	P29474	NOS3	P11309	PIM1	S615	R612C	612	Missense	distal	-3	no	0.002	0.001	EPSD	TCGA;ICGC;COSMIC	0.001	Down-regulation
CAMK_PIM_PIM1_ST	P29474	NOS3	P11309	PIM1	S615	R612H	612	Missense	distal	-3	no	0.002	0.001	EPSD	TCGA;ICGC;COSMIC	0.001	Down-regulation
CAMK_PIM_PIM1_ST	P29474	NOS3	P11309	PIM1	S617	R612C	612	Missense	distal	-5	no	0.001	0.000	EPSD	TCGA;ICGC;COSMIC	0.001	Loss
CAMK_PIM_PIM1_ST	P29474	NOS3	P11309	PIM1	S617	S617F	617	Missense	central	0	yes	0.001	0.000	EPSD	TCGA;ICGC;COSMIC;GDSC	0.001	Loss
CAMK_PIM_PIM1_ST	P29474	NOS3	P11309	PIM1	S617	R612H	612	Missense	distal	-5	no	0.001	0.000	EPSD	TCGA;ICGC;COSMIC	0.001	Loss
CAMK_PIM_PIM1_ST	P29474	NOS3	P11309	PIM1	T1175	R1172H	1172	Missense	distal	-3	no	0.001	0.000	EPSD	TCGA;ICGC;COSMIC;GDSC;CCLE	0.001	Loss
CAMK_PIM_PIM1_ST	P29474	NOS3	P11309	PIM1	S1177	R1172H	1172	Missense	distal	-5	no	0.002	0.001	EPSD	TCGA;ICGC;COSMIC;GDSC;CCLE	0.001	Down-regulation
CAMK_PIM_PIM1_ST	P29474	NOS3	P11309	PIM1	S1179	R1174H	1174	Missense	distal	-5	no	0.002	0.000	EPSD	TCGA;ICGC	0.001	Loss
CAMK_PIM_PIM1_ST	Q9Y4H2	IRS2	P11309	PIM1	S304	S304R	304	Missense	central	0	yes	0.001	0.000	EPSD	TCGA;ICGC;COSMIC	0.001	Loss
CAMK_PIM_PIM1_ST	Q9Y4H2	IRS2	P11309	PIM1	S309	S304R	304	Missense	distal	-5	no	0.000	0.001	EPSD	TCGA;ICGC;COSMIC	0.001	Gain
CAMK_PIM_PIM1_ST	Q9Y4H2	IRS2	P11309	PIM1	S560	R557H	557	Missense	distal	-3	no	0.001	0.000	EPSD	TCGA;ICGC	0.001	Loss
CAMK_PIM_PIM1_ST	Q9Y4H2	IRS2	P11309	PIM1	T575	R572H	572	Missense	distal	-3	no	0.001	0.000	EPSD	TCGA;ICGC;COSMIC	0.001	Loss
CAMK_PIM_PIM1_ST	Q9Y4H2	IRS2	P11309	PIM1	S577	R572H	572	Missense	distal	-5	no	0.003	0.001	EPSD	TCGA;ICGC;COSMIC	0.001	Down-regulation
CAMK_PIM_PIM1_ST	Q9Y4H2	IRS2	P11309	PIM1	S577	R574K	574	Missense	distal	-3	no	0.003	0.002	EPSD	TCGA;ICGC;COSMIC	0.001	Down-regulation
CAMK_PIM_PIM1_ST	Q9Y4H2	IRS2	P11309	PIM1	T579	T579I	579	Missense	central	0	yes	0.001	0.000	EPSD	TCGA;ICGC	0.001	Loss
CAMK_PIM_PIM1_ST	Q9Y4H2	IRS2	P11309	PIM1	T1102	T1102A	1102	Missense	central	0	yes	0.001	0.000	EPSD	TCGA;ICGC	0.001	Loss
CAMK_PIM_PIM1_ST	Q9Y4H2	IRS2	P11309	PIM1	S1153	E1150K	1150	Missense	distal	-3	no	0.000	0.001	EPSD	TCGA;ICGC;COSMIC	0.001	Gain
CAMK_PIM_PIM1_ST	Q9Y4H2	IRS2	P11309	PIM1	T1155	E1150K	1150	Missense	distal	-5	no	0.000	0.001	EPSD	TCGA;ICGC;COSMIC	0.001	Gain
CAMK_PIM_PIM1_ST	Q9Y4H2	IRS2	P11309	PIM1	T1243	R1240H	1240	Missense	distal	-3	no	0.001	0.000	EPSD	TCGA;ICGC;COSMIC	0.001	Loss
CAMK_PIM_PIM1_ST	Q9Y4H2	IRS2	P11309	PIM1	S1244	R1241T	1241	Missense	distal	-3	no	0.001	0.000	EPSD	TCGA;ICGC;COSMIC	0.001	Loss
CAMK_PIM_PIM1_ST	O60381	HBP1	P11309	PIM1	S156	R151H	151	Missense	distal	-5	no	0.001	0.000	EPSD	TCGA;ICGC;COSMIC;CCLE	0.001	Loss
CAMK_PIM_PIM1_ST	O60381	HBP1	P11309	PIM1	S380	R377H	377	Missense	distal	-3	no	0.003	0.002	PhosphoSitePlus;EPSD	TCGA;ICGC;COSMIC	0.001	Down-regulation
CAMK_PIM_PIM1_ST	O60381	HBP1	P11309	PIM1	S380	R375C	375	Missense	distal	-5	no	0.003	0.001	PhosphoSitePlus;EPSD	TCGA;ICGC;COSMIC	0.001	Down-regulation
CAMK_PIM_PIM1_ST	O60381	HBP1	P11309	PIM1	S382	R377H	377	Missense	distal	-5	no	0.001	0.000	EPSD	TCGA;ICGC;COSMIC	0.001	Loss
CAMK_PIM_PIM1_ST	O60381	HBP1	P11309	PIM1	S509	R506I	506	Missense	distal	-3	no	0.002	0.001	EPSD	TCGA;ICGC	0.001	Down-regulation
CAMK_PIM_PIM1_ST	Q99801	NKX3-1	P11309	PIM1	S185	K182M	182	Missense	distal	-3	no	0.002	0.001	EPSD;PhosphoSitePlus	TCGA;ICGC	0.001	Down-regulation
CAMK_PIM_PIM1_ST	Q99801	NKX3-1	P11309	PIM1	S186	R181Q	181	Missense	distal	-5	no	0.002	0.001	PhosphoSitePlus;EPSD	TCGA;COSMIC	0.001	Down-regulation
CAMK_PIM_PIM1_ST	Q99801	NKX3-1	P11309	PIM1	S195	E192K	192	Missense	distal	-3	no	0.000	0.001	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	0.001	Gain
CAMK_PIM_PIM1_ST	Q99801	NKX3-1	P11309	PIM1	S196	S196F	196	Missense	central	0	yes	0.001	0.000	EPSD;PhosphoSitePlus	TCGA;COSMIC	0.001	Loss
CAMK_PIM_PIM1_ST	Q9UNQ0	ABCG2	P11309	PIM1	S50	R45Q	45	Missense	distal	-5	no	0.002	0.001	EPSD	TCGA;ICGC;COSMIC	0.001	Down-regulation
CAMK_PIM_PIM1_ST	Q9UNQ0	ABCG2	P11309	PIM1	T194	G189R	189	Missense	distal	-5	no	0.001	0.003	EPSD	TCGA;ICGC;COSMIC	0.001	Up-regulation
CAMK_PIM_PIM1_ST	Q9UNQ0	ABCG2	P11309	PIM1	S248	P245R	245	Missense	distal	-3	no	0.000	0.001	EPSD	TCGA;ICGC;COSMIC	0.001	Gain
CAMK_PIM_PIM1_ST	Q04206	RELA	P11309	PIM1	S42	E39K	39	Missense	distal	-3	no	0.001	0.002	EPSD	TCGA;ICGC;COSMIC	0.001	Up-regulation
CAMK_PIM_PIM1_ST	Q04206	RELA	P11309	PIM1	T136	R133H	133	Missense	distal	-3	no	0.001	0.000	EPSD	TCGA;ICGC;COSMIC	0.001	Loss
CAMK_PIM_PIM1_ST	Q04206	RELA	P11309	PIM1	T191	N186K	186	Missense	distal	-5	no	0.000	0.001	EPSD	TCGA;ICGC;COSMIC	0.001	Gain
CAMK_PIM_PIM1_ST	Q04206	RELA	P11309	PIM1	S276	S276F	276	Missense	central	0	yes	0.001	0.000	PhosphoSitePlus	TCGA;ICGC;COSMIC	0.001	Loss
CAMK_PIM_PIM1_ST	Q04206	RELA	P11309	PIM1	S276	R273W	273	Missense	distal	-3	no	0.001	0.000	PhosphoSitePlus	TCGA;ICGC	0.001	Loss
CAMK_PIM_PIM1_ST	Q04206	RELA	P11309	PIM1	T308	T308A	308	Missense	central	0	yes	0.001	0.000	EPSD	TCGA;ICGC;COSMIC	0.001	Loss
CAMK_PIM_PIM1_ST	P10275	AR	P11309	PIM1	S16	R13G	13	Missense	distal	-3	no	0.001	0.000	EPSD	TCGA;ICGC;COSMIC	0.001	Loss
CAMK_PIM_PIM1_ST	P10275	AR	P11309	PIM1	T18	R13G	13	Missense	distal	-5	no	0.001	0.000	EPSD	TCGA;ICGC;COSMIC	0.001	Loss
CAMK_PIM_PIM1_ST	P10275	AR	P11309	PIM1	S244	S244L	244	Missense	central	0	yes	0.001	0.000	EPSD	TCGA;ICGC;COSMIC;GDSC;CCLE	0.001	Loss
CAMK_PIM_PIM1_ST	P10275	AR	P11309	PIM1	S244	S244A	244	Missense	central	0	yes	0.001	0.000	EPSD	TCGA;ICGC;COSMIC	0.001	Loss
CAMK_PIM_PIM1_ST	P10275	AR	P11309	PIM1	S328	E323K	323	Missense	distal	-5	no	0.000	0.001	EPSD	TCGA;ICGC;GDSC;CCLE	0.001	Gain
CAMK_PIM_PIM1_ST	P10275	AR	P11309	PIM1	S648	E645K	645	Missense	distal	-3	no	0.000	0.001	EPSD	TCGA;ICGC;COSMIC	0.001	Gain
CAMK_PIM_PIM1_ST	P10275	AR	P11309	PIM1	T650	E645K	645	Missense	distal	-5	no	0.000	0.001	EPSD	TCGA;ICGC;COSMIC	0.001	Gain
CAMK_PIM_PIM1_ST	P10275	AR	P11309	PIM1	S792	R787Q	787	Missense	distal	-5	no	0.002	0.001	EPSD	TCGA;ICGC;COSMIC	0.001	Down-regulation
STE_STE20_MST_STK4_ST	Q14457	BECN1	Q13043	STK4	S7	S4T	4	Missense	distal	-3	no	4.905	4.948	EPSD	TCGA;ICGC;COSMIC	4.850	Up-regulation
STE_STE20_MST_STK4_ST	Q14457	BECN1	Q13043	STK4	S10	S4T	4	Missense	distal	-6	no	4.885	4.898	EPSD	TCGA;ICGC;COSMIC	4.850	Up-regulation
STE_STE20_MST_STK4_ST	Q14457	BECN1	Q13043	STK4	S10	F16L	16	Missense	distal	6	no	4.885	4.882	EPSD	TCGA;ICGC;COSMIC	4.850	Down-regulation
STE_STE20_MST_STK4_ST	Q14457	BECN1	Q13043	STK4	T11	S4T	4	Missense	distal	-7	no	4.982	4.978	EPSD	TCGA;ICGC;COSMIC	4.850	Down-regulation
STE_STE20_MST_STK4_ST	Q14457	BECN1	Q13043	STK4	T11	F16L	16	Missense	distal	5	no	4.982	4.969	EPSD	TCGA;ICGC;COSMIC	4.850	Down-regulation
STE_STE20_MST_STK4_ST	Q14457	BECN1	Q13043	STK4	S15	F16L	16	Missense	proximal	1	no	4.947	4.963	EPSD	TCGA;ICGC;COSMIC	4.850	Up-regulation
STE_STE20_MST_STK4_ST	Q14457	BECN1	Q13043	STK4	T91	P84L	84	Missense	distal	-7	no	4.851	4.850	EPSD	TCGA;ICGC;COSMIC	4.850	Down-regulation
STE_STE20_MST_STK4_ST	Q14457	BECN1	Q13043	STK4	T91	T98P	98	Missense	distal	7	no	4.851	4.855	EPSD	TCGA;ICGC;COSMIC	4.850	Up-regulation
STE_STE20_MST_STK4_ST	Q14457	BECN1	Q13043	STK4	T108	R114Q	114	Missense	distal	6	no	4.899	4.888	PhosphoSitePlus	TCGA;ICGC;COSMIC	4.850	Down-regulation
STE_STE20_MST_STK4_ST	Q14457	BECN1	Q13043	STK4	S409	I403T	403	Missense	distal	-6	no	4.872	4.873	EPSD	TCGA;ICGC;COSMIC	4.850	Up-regulation
STE_STE20_MST_STK4_ST	Q14457	BECN1	Q13043	STK4	S409	G411S	411	Missense	proximal	2	no	4.872	4.885	EPSD	TCGA;ICGC;COSMIC	4.850	Up-regulation
STE_STE20_MST_STK4_ST	Q14457	BECN1	Q13043	STK4	S409	I403N	403	Missense	distal	-6	no	4.872	4.868	EPSD	TCGA;ICGC;COSMIC	4.850	Down-regulation
STE_STE20_MST_STK4_ST	Q14457	BECN1	Q13043	STK4	T417	E422K	422	Missense	distal	5	no	4.873	4.858	EPSD	TCGA;ICGC;COSMIC	4.850	Down-regulation
STE_STE20_MST_STK4_ST	Q14457	BECN1	Q13043	STK4	T417	G411S	411	Missense	distal	-6	no	4.873	4.877	EPSD	TCGA;ICGC;COSMIC	4.850	Up-regulation
STE_STE20_MST_STK4_ST	Q06830	PRDX1	Q13043	STK4	T18	M21T	21	Missense	distal	3	no	4.889	4.882	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	4.850	Down-regulation
STE_STE20_MST_STK4_ST	Q06830	PRDX1	Q13043	STK4	T18	A19T	19	Missense	proximal	1	no	4.889	4.888	EPSD;PhosphoSitePlus	TCGA	4.850	Down-regulation
STE_STE20_MST_STK4_ST	Q06830	PRDX1	Q13043	STK4	T18	F15L	15	Missense	distal	-3	no	4.889	4.881	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	4.850	Down-regulation
STE_STE20_MST_STK4_ST	P19429	TNNI3	Q13043	STK4	S5	A2E	2	Missense	distal	-3	no	4.878	4.895	EPSD	TCGA;ICGC;COSMIC	4.850	Up-regulation
STE_STE20_MST_STK4_ST	P19429	TNNI3	Q13043	STK4	S23	I19T	19	Missense	distal	-4	no	4.968	4.967	EPSD	TCGA;ICGC;COSMIC	4.850	Down-regulation
STE_STE20_MST_STK4_ST	P19429	TNNI3	Q13043	STK4	S23	Y29H	29	Missense	distal	6	no	4.968	4.975	EPSD	TCGA;ICGC;COSMIC	4.850	Up-regulation
STE_STE20_MST_STK4_ST	P19429	TNNI3	Q13043	STK4	S23	R21C	21	Missense	proximal	-2	no	4.968	4.952	EPSD	TCGA	4.850	Down-regulation
STE_STE20_MST_STK4_ST	P19429	TNNI3	Q13043	STK4	S23	R22H	22	Missense	proximal	-1	no	4.968	4.967	EPSD	TCGA;ICGC	4.850	Down-regulation
STE_STE20_MST_STK4_ST	P19429	TNNI3	Q13043	STK4	S77	S77N	77	Missense	central	0	yes	4.877	0.000	EPSD	TCGA	4.850	Loss
STE_STE20_MST_STK4_ST	P19429	TNNI3	Q13043	STK4	T129	E124K	124	Missense	distal	-5	no	4.821	4.850	PhosphoSitePlus;EPSD	TCGA;COSMIC	4.850	Gain
STE_STE20_MST_STK4_ST	P19429	TNNI3	Q13043	STK4	T143	R141W	141	Missense	proximal	-2	no	4.934	4.918	EPSD;PhosphoSitePlus	TCGA	4.850	Down-regulation
STE_STE20_MST_STK4_ST	P19429	TNNI3	Q13043	STK4	T143	R145Q	145	Missense	proximal	2	no	4.934	4.879	EPSD;PhosphoSitePlus	TCGA;COSMIC;GDSC;CCLE	4.850	Down-regulation
STE_STE20_MST_STK4_ST	Q13043	STK4	Q13043	STK4	S21	K16R	16	Missense	distal	-5	no	4.871	4.799	EPSD	TCGA;ICGC;COSMIC	4.850	Loss
STE_STE20_MST_STK4_ST	Q13043	STK4	Q13043	STK4	T23	K16R	16	Missense	distal	-7	no	4.974	4.979	EPSD	TCGA;ICGC;COSMIC	4.850	Up-regulation
STE_STE20_MST_STK4_ST	Q13043	STK4	Q13043	STK4	S307	Q305H	305	Missense	proximal	-2	no	4.846	4.853	EPSD	TCGA;COSMIC	4.850	Gain
STE_STE20_MST_STK4_ST	Q13043	STK4	Q13043	STK4	S327	D323N	323	Missense	distal	-4	no	4.895	4.894	EPSD	TCGA;COSMIC	4.850	Down-regulation
STE_STE20_MST_STK4_ST	Q13043	STK4	Q13043	STK4	S422	W425C	425	Missense	distal	3	no	4.854	4.836	EPSD	TCGA;COSMIC	4.850	Loss
STE_STE20_MST_STK4_ST	Q13043	STK4	Q13043	STK4	T440	D443N	443	Missense	distal	3	no	4.856	4.834	EPSD	TCGA;COSMIC	4.850	Loss
STE_STE20_MST_STK4_ST	Q13043	STK4	Q13043	STK4	T440	D443G	443	Missense	distal	3	no	4.856	4.852	EPSD	TCGA;COSMIC	4.850	Down-regulation
STE_STE20_MST_STK4_ST	Q13043	STK4	Q13043	STK4	T440	K437N	437	Missense	distal	-3	no	4.856	4.823	EPSD	TCGA;COSMIC	4.850	Loss
STE_STE20_MST_STK4_ST	Q13043	STK4	Q13043	STK4	T440	E434K	434	Missense	distal	-6	no	4.856	4.851	EPSD	TCGA	4.850	Down-regulation
STE_STE20_MST_STK4_ST	O43524	FOXO3	Q13043	STK4	S200	G205S	205	Missense	distal	5	no	4.885	4.968	EPSD	TCGA;ICGC;COSMIC	4.850	Up-regulation
STE_STE20_MST_STK4_ST	O43524	FOXO3	Q13043	STK4	S209	S209F	209	Missense	central	0	yes	5.012	0.000	EPSD;PhosphoSitePlus	TCGA;ICGC	4.850	Loss
STE_STE20_MST_STK4_ST	O43524	FOXO3	Q13043	STK4	S209	S209Y	209	Missense	central	0	yes	5.012	0.000	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	4.850	Loss
STE_STE20_MST_STK4_ST	O43524	FOXO3	Q13043	STK4	S215	S209F	209	Missense	distal	-6	no	4.998	4.999	EPSD;PhosphoSitePlus	TCGA;ICGC	4.850	Up-regulation
STE_STE20_MST_STK4_ST	O43524	FOXO3	Q13043	STK4	S215	R222W	222	Missense	distal	7	no	4.998	5.005	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC;GDSC;CCLE	4.850	Up-regulation
STE_STE20_MST_STK4_ST	O43524	FOXO3	Q13043	STK4	S215	S209Y	209	Missense	distal	-6	no	4.998	5.006	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	4.850	Up-regulation
STE_STE20_MST_STK4_ST	O43524	FOXO3	Q13043	STK4	T228	R222W	222	Missense	distal	-6	no	4.912	4.920	EPSD	TCGA;ICGC;COSMIC;GDSC;CCLE	4.850	Up-regulation
STE_STE20_MST_STK4_ST	O43524	FOXO3	Q13043	STK4	S243	R248Q	248	Missense	distal	5	no	5.018	5.015	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	4.850	Down-regulation
STE_STE20_MST_STK4_ST	O43524	FOXO3	Q13043	STK4	S243	G244R	244	Missense	proximal	1	no	5.018	4.952	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	4.850	Down-regulation
STE_STE20_MST_STK4_ST	O43524	FOXO3	Q13043	STK4	S243	G241A	241	Missense	proximal	-2	no	5.018	5.040	EPSD;PhosphoSitePlus	TCGA	4.850	Up-regulation
STE_STE20_MST_STK4_ST	O43524	FOXO3	Q13043	STK4	S243	G244A	244	Missense	proximal	1	no	5.018	4.960	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	4.850	Down-regulation
STE_STE20_MST_STK4_ST	O43524	FOXO3	Q13043	STK4	S243	R250W	250	Missense	distal	7	no	5.018	5.024	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	4.850	Up-regulation
STE_STE20_MST_STK4_ST	O43524	FOXO3	Q13043	STK4	S243	R250Q	250	Missense	distal	7	no	5.018	5.025	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	4.850	Up-regulation
STE_STE20_MST_STK4_ST	O43524	FOXO3	Q13043	STK4	S344	A341V	341	Missense	distal	-3	no	4.852	4.843	EPSD	TCGA;ICGC;COSMIC	4.850	Loss
STE_STE20_MST_STK4_ST	O43524	FOXO3	Q13043	STK4	T395	P397S	397	Missense	proximal	2	no	4.928	4.922	EPSD	TCGA;ICGC;COSMIC	4.850	Down-regulation
STE_STE20_MST_STK4_ST	O43524	FOXO3	Q13043	STK4	T395	P397L	397	Missense	proximal	2	no	4.928	4.926	EPSD	TCGA;ICGC;COSMIC	4.850	Down-regulation
STE_STE20_MST_STK4_ST	O43524	FOXO3	Q13043	STK4	T395	D392G	392	Missense	distal	-3	no	4.928	4.912	EPSD	TCGA;ICGC;COSMIC	4.850	Down-regulation
STE_STE20_MST_STK4_ST	O43524	FOXO3	Q13043	STK4	T395	S402L	402	Missense	distal	7	no	4.928	4.924	EPSD	TCGA;ICGC;COSMIC	4.850	Down-regulation
STE_STE20_MST_STK4_ST	O43524	FOXO3	Q13043	STK4	S421	L423M	423	Missense	proximal	2	no	4.896	4.903	EPSD	TCGA;ICGC	4.850	Up-regulation
STE_STE20_MST_STK4_ST	O43524	FOXO3	Q13043	STK4	S421	S425F	425	Missense	distal	4	no	4.896	4.859	EPSD	TCGA;ICGC;COSMIC	4.850	Down-regulation
STE_STE20_MST_STK4_ST	Q14653	IRF3	Q13043	STK4	S259	T253K	253	Missense	distal	-6	no	4.918	4.919	EPSD	TCGA;COSMIC	4.850	Up-regulation
STE_STE20_MST_STK4_ST	Q14653	IRF3	Q13043	STK4	S259	V261A	261	Missense	proximal	2	no	4.918	4.939	EPSD	TCGA;COSMIC	4.850	Up-regulation
STE_STE20_MST_STK4_ST	Q7L9L4	MOB1B	Q13043	STK4	S10	K16T	16	Missense	distal	6	no	4.957	4.948	EPSD	TCGA;ICGC;COSMIC	4.850	Down-regulation
STE_STE20_MST_STK4_ST	Q7L9L4	MOB1B	Q13043	STK4	T12	K16T	16	Missense	distal	4	no	4.944	4.942	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	4.850	Down-regulation
STE_STE20_MST_STK4_ST	Q7L9L4	MOB1B	Q13043	STK4	S23	K16T	16	Missense	distal	-7	no	4.851	4.852	EPSD	TCGA;ICGC;COSMIC	4.850	Up-regulation
STE_STE20_MST_STK4_ST	P17301	ITGA2	Q13043	STK4	S601	I596V	596	Missense	distal	-5	no	4.924	4.941	EPSD	TCGA;ICGC;COSMIC	4.850	Up-regulation
STE_STE20_MST_STK4_ST	P17301	ITGA2	Q13043	STK4	S601	R597C	597	Missense	distal	-4	no	4.924	4.925	EPSD	TCGA;ICGC;COSMIC	4.850	Up-regulation
STE_STE20_MST_STK4_ST	P17301	ITGA2	Q13043	STK4	S601	I604L	604	Missense	distal	3	no	4.924	4.934	EPSD	TCGA;ICGC;COSMIC	4.850	Up-regulation
STE_STE20_MST_STK4_ST	P17301	ITGA2	Q13043	STK4	S601	I604T	604	Missense	distal	3	no	4.924	4.926	EPSD	TCGA;ICGC;COSMIC	4.850	Up-regulation
STE_STE20_MST_STK4_ST	P17301	ITGA2	Q13043	STK4	S1036	S1036F	1036	Missense	central	0	yes	4.901	0.000	EPSD	TCGA;ICGC;COSMIC	4.850	Loss
STE_STE20_MST_STK4_ST	P17301	ITGA2	Q13043	STK4	S1036	G1029V	1029	Missense	distal	-7	no	4.901	4.899	EPSD	TCGA;ICGC;COSMIC	4.850	Down-regulation
STE_STE20_MST_STK4_ST	Q15208	STK38	Q13043	STK4	T21	T26S	26	Missense	distal	5	no	4.934	5.109	EPSD	TCGA;ICGC;COSMIC	4.850	Up-regulation
STE_STE20_MST_STK4_ST	Q15208	STK38	Q13043	STK4	T21	E28D	28	Missense	distal	7	no	4.934	4.954	EPSD	TCGA;ICGC;COSMIC	4.850	Up-regulation
STE_STE20_MST_STK4_ST	Q15208	STK38	Q13043	STK4	T23	T26S	26	Missense	distal	3	no	4.892	4.902	EPSD	TCGA;ICGC;COSMIC	4.850	Up-regulation
STE_STE20_MST_STK4_ST	Q15208	STK38	Q13043	STK4	T23	E28D	28	Missense	distal	5	no	4.892	4.895	EPSD	TCGA;ICGC;COSMIC	4.850	Up-regulation
STE_STE20_MST_STK4_ST	Q15208	STK38	Q13043	STK4	T26	E28D	28	Missense	proximal	2	no	4.858	4.807	EPSD	TCGA;ICGC;COSMIC	4.850	Loss
STE_STE20_MST_STK4_ST	Q15208	STK38	Q13043	STK4	S252	D256N	256	Missense	distal	4	no	4.928	4.946	EPSD	TCGA;ICGC;COSMIC	4.850	Up-regulation
STE_STE20_MST_STK4_ST	Q15208	STK38	Q13043	STK4	S252	H251Y	251	Missense	proximal	-1	no	4.928	4.926	EPSD	TCGA;ICGC;COSMIC	4.850	Down-regulation
Other_MOS_MOS_ST	P08670	VIM	P00540	MOS	S29	S22I	22	Missense	distal	-7	no	2.419	2.710	EPSD	TCGA;ICGC;COSMIC	2.415	Up-regulation
Other_MOS_MOS_ST	P08670	VIM	P00540	MOS	S29	T33M	33	Missense	distal	4	no	2.419	2.335	EPSD	TCGA;ICGC;COSMIC	2.415	Loss
Other_MOS_MOS_ST	P08670	VIM	P00540	MOS	T458	E457K	457	Missense	proximal	-1	no	2.469	2.491	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC;CCLE	2.415	Up-regulation
Other_MOS_MOS_ST	P08670	VIM	P00540	MOS	S459	E457K	457	Missense	proximal	-2	no	2.783	2.751	PhosphoSitePlus;EPSD	TCGA;ICGC;COSMIC;CCLE	2.415	Down-regulation
STE_STE20_KHS_MAP4K3_ST	Q04759	PRKCQ	Q8IVH8	MAP4K3	S297	R302L	302	Missense	distal	5	no	3.094	3.002	EPSD	TCGA;ICGC;COSMIC	2.839	Down-regulation
STE_STE20_KHS_MAP4K3_ST	Q04759	PRKCQ	Q8IVH8	MAP4K3	S297	A291V	291	Missense	distal	-6	no	3.094	3.020	EPSD	TCGA;ICGC;COSMIC	2.839	Down-regulation
STE_STE20_KHS_MAP4K3_ST	Q04759	PRKCQ	Q8IVH8	MAP4K3	T538	T538N	538	Missense	central	0	yes	8.554	0.000	PhosphoSitePlus	TCGA;ICGC;COSMIC	2.839	Loss
STE_STE20_KHS_MAP4K3_ST	Q04759	PRKCQ	Q8IVH8	MAP4K3	T538	G541V	541	Missense	distal	3	no	8.554	5.163	PhosphoSitePlus	TCGA;ICGC;COSMIC	2.839	Down-regulation
STE_STE20_KHS_MAP4K3_ST	Q04759	PRKCQ	Q8IVH8	MAP4K3	T538	P543T	543	Missense	distal	5	no	8.554	8.471	PhosphoSitePlus	TCGA;ICGC	2.839	Down-regulation
STE_STE20_KHS_MAP4K3_ST	P19484	TFEB	Q8IVH8	MAP4K3	S3	R8C	8	Missense	distal	5	no	8.626	8.564	PhosphoSitePlus	TCGA;ICGC;COSMIC	2.839	Down-regulation
STE_STE20_KHS_MAP4K3_ST	P19484	TFEB	Q8IVH8	MAP4K3	S3	R4H	4	Missense	proximal	1	no	8.626	8.617	PhosphoSitePlus	TCGA;ICGC;COSMIC;CCLE	2.839	Down-regulation
STE_STE20_KHS_MAP4K3_ST	P19484	TFEB	Q8IVH8	MAP4K3	S3	S3P	3	Missense	central	0	yes	8.626	0.000	PhosphoSitePlus	TCGA;ICGC	2.839	Loss
STE_STE20_KHS_MAP4K3_ST	P19484	TFEB	Q8IVH8	MAP4K3	S133	A135T	135	Missense	proximal	2	no	2.928	2.929	EPSD	TCGA;ICGC;COSMIC;GDSC;CCLE	2.839	Up-regulation
STE_STE20_KHS_MAP4K3_ST	Q8IVH8	MAP4K3	Q8IVH8	MAP4K3	T145	L144F	144	Missense	proximal	-1	no	2.899	2.892	EPSD	TCGA;ICGC;COSMIC	2.839	Down-regulation
STE_STE20_KHS_MAP4K3_ST	Q8IVH8	MAP4K3	Q8IVH8	MAP4K3	S170	R168W	168	Missense	proximal	-2	no	10.328	10.299	PhosphoSitePlus	TCGA;ICGC;COSMIC	2.839	Down-regulation
STE_STE20_KHS_MAP4K3_ST	Q8IVH8	MAP4K3	Q8IVH8	MAP4K3	S170	I172V	172	Missense	proximal	2	no	10.328	10.152	PhosphoSitePlus	TCGA;COSMIC	2.839	Down-regulation
STE_STE20_KHS_MAP4K3_ST	Q8IVH8	MAP4K3	Q8IVH8	MAP4K3	S295	H294L	294	Missense	proximal	-1	no	3.145	3.150	EPSD	TCGA;COSMIC	2.839	Up-regulation
STE_STE20_KHS_MAP4K3_ST	Q8IVH8	MAP4K3	Q8IVH8	MAP4K3	S295	D293Y	293	Missense	proximal	-2	no	3.145	3.144	EPSD	TCGA;COSMIC	2.839	Down-regulation
PKL_FJ_FAM20C_ST	Q9GZV9	FGF23	Q8IXL6	FAM20C	S180	R175Q	175	Missense	distal	-5	no	6.631	6.603	PhosphoSitePlus	TCGA;ICGC;COSMIC	2.180	Down-regulation
PKL_FJ_FAM20C_ST	Q9GZV9	FGF23	Q8IXL6	FAM20C	S180	S185L	185	Missense	distal	5	no	6.631	6.668	PhosphoSitePlus	TCGA;ICGC;COSMIC	2.180	Up-regulation
PKL_FJ_FAM20C_ST	Q9GZV9	FGF23	Q8IXL6	FAM20C	S180	R179Q	179	Missense	proximal	-1	no	6.631	6.425	PhosphoSitePlus	TCGA;ICGC;COSMIC	2.180	Down-regulation
PKL_FJ_FAM20C_ST	Q9GZV9	FGF23	Q8IXL6	FAM20C	S180	S180R	180	Missense	central	0	yes	6.631	0.000	PhosphoSitePlus	TCGA;ICGC;COSMIC	2.180	Loss
PKL_FJ_FAM20C_ST	Q9GZV9	FGF23	Q8IXL6	FAM20C	S180	R176Q	176	Missense	distal	-4	no	6.631	6.555	PhosphoSitePlus	TCGA;ICGC;COSMIC	2.180	Down-regulation
PKL_FJ_FAM20C_ST	Q9GZV9	FGF23	Q8IXL6	FAM20C	S180	R187W	187	Missense	distal	7	no	6.631	6.539	PhosphoSitePlus	TCGA;ICGC;COSMIC	2.180	Down-regulation
PKL_FJ_FAM20C_ST	Q9GZV9	FGF23	Q8IXL6	FAM20C	S180	A181T	181	Missense	proximal	1	no	6.631	6.367	PhosphoSitePlus	TCGA;ICGC;COSMIC	2.180	Down-regulation
PKL_FJ_FAM20C_ST	P23327	HRC	Q8IXL6	FAM20C	S96	G100V	100	Missense	distal	4	no	6.169	6.230	PhosphoSitePlus	TCGA;ICGC;COSMIC	2.180	Up-regulation
PKL_FJ_FAM20C_ST	P23327	HRC	Q8IXL6	FAM20C	S96	K90N	90	Missense	distal	-6	no	6.169	6.182	PhosphoSitePlus	TCGA;ICGC;COSMIC	2.180	Up-regulation
PKL_FJ_FAM20C_ST	P23327	HRC	Q8IXL6	FAM20C	S96	L102P	102	Missense	distal	6	no	6.169	6.199	PhosphoSitePlus	TCGA;ICGC;COSMIC	2.180	Up-regulation
PKL_FJ_FAM20C_ST	P23327	HRC	Q8IXL6	FAM20C	S96	E91D	91	Missense	distal	-5	no	6.169	6.135	PhosphoSitePlus	TCGA;ICGC;COSMIC	2.180	Down-regulation
PKL_FJ_FAM20C_ST	P23327	HRC	Q8IXL6	FAM20C	S263	R267G	267	Missense	distal	4	no	2.405	2.342	EPSD	TCGA;ICGC;COSMIC	2.180	Down-regulation
PKL_FJ_FAM20C_ST	P23327	HRC	Q8IXL6	FAM20C	S501	D498N	498	Missense	distal	-3	no	2.419	2.413	EPSD	TCGA;ICGC;COSMIC	2.180	Down-regulation
PKL_FJ_FAM20C_ST	P23327	HRC	Q8IXL6	FAM20C	S501	E503Q	503	Missense	proximal	2	no	2.419	2.057	EPSD	TCGA;ICGC;COSMIC	2.180	Loss
PKL_FJ_FAM20C_ST	P23327	HRC	Q8IXL6	FAM20C	S501	S494C	494	Missense	distal	-7	no	2.419	2.540	EPSD	TCGA;ICGC;COSMIC	2.180	Up-regulation
TK_Eph_EPHA4_Y	P54764	EPHA4	P54764	EPHA4	Y602	P605S	605	Missense	distal	3	no	4.080	4.004	PhosphoSitePlus;EPSD	TCGA;ICGC;COSMIC	1.226	Down-regulation
TK_Eph_EPHA4_Y	P54764	EPHA4	P54764	EPHA4	Y779	P775T	775	Missense	distal	-4	no	4.985	4.973	EPSD	TCGA;ICGC;COSMIC	1.226	Down-regulation
TK_Eph_EPHA4_Y	P54764	EPHA4	P54764	EPHA4	Y779	G784C	784	Missense	distal	5	no	4.985	4.919	EPSD	TCGA;ICGC;COSMIC	1.226	Down-regulation
TK_Eph_EPHA4_Y	P54764	EPHA4	P54764	EPHA4	Y779	D773N	773	Missense	distal	-6	no	4.985	5.004	EPSD	TCGA;ICGC;COSMIC	1.226	Up-regulation
CMGC_MAPK_ERK3_MAPK6_ST	Q9Y6Q9	NCOA3	Q16659	MAPK6	S32	R36W	36	Missense	distal	4	no	2.473	2.382	EPSD	TCGA;ICGC;COSMIC;GDSC	2.026	Down-regulation
CMGC_MAPK_ERK3_MAPK6_ST	Q9Y6Q9	NCOA3	Q16659	MAPK6	S543	S542L	542	Missense	proximal	-1	no	2.188	2.240	EPSD	TCGA;ICGC;COSMIC	2.026	Up-regulation
CMGC_MAPK_ERK3_MAPK6_ST	Q9Y6Q9	NCOA3	Q16659	MAPK6	S543	S536F	536	Missense	distal	-7	no	2.188	2.206	EPSD	TCGA;ICGC;COSMIC	2.026	Up-regulation
CMGC_MAPK_ERK3_MAPK6_ST	Q9Y6Q9	NCOA3	Q16659	MAPK6	S543	S539F	539	Missense	distal	-4	no	2.188	2.158	EPSD	TCGA;ICGC;COSMIC	2.026	Down-regulation
CMGC_MAPK_ERK3_MAPK6_ST	Q9Y6Q9	NCOA3	Q16659	MAPK6	S615	P612H	612	Missense	distal	-3	no	2.468	2.467	EPSD	TCGA;ICGC;COSMIC	2.026	Down-regulation
CMGC_MAPK_ERK3_MAPK6_ST	Q9Y6Q9	NCOA3	Q16659	MAPK6	S615	E614G	614	Missense	proximal	-1	no	2.468	2.472	EPSD	TCGA;ICGC;COSMIC	2.026	Up-regulation
CMGC_MAPK_ERK3_MAPK6_ST	Q9Y6Q9	NCOA3	Q16659	MAPK6	S640	K647R	647	Missense	distal	7	no	2.062	2.059	EPSD	TCGA;ICGC;COSMIC	2.026	Down-regulation
CMGC_MAPK_ERK3_MAPK6_ST	Q9Y6Q9	NCOA3	Q16659	MAPK6	S640	S644L	644	Missense	distal	4	no	2.062	1.780	EPSD	TCGA;COSMIC	2.026	Loss
CMGC_MAPK_ERK3_MAPK6_ST	Q9Y6Q9	NCOA3	Q16659	MAPK6	S652	K647R	647	Missense	distal	-5	no	2.249	2.265	EPSD	TCGA;ICGC;COSMIC	2.026	Up-regulation
CMGC_MAPK_ERK3_MAPK6_ST	Q9Y6Q9	NCOA3	Q16659	MAPK6	S655	S662C	662	Missense	distal	7	no	2.252	2.253	EPSD	TCGA;COSMIC	2.026	Up-regulation
CMGC_MAPK_ERK3_MAPK6_ST	Q9Y6Q9	NCOA3	Q16659	MAPK6	T663	S662C	662	Missense	proximal	-1	no	2.516	2.474	EPSD	TCGA;COSMIC	2.026	Down-regulation
CMGC_MAPK_ERK3_MAPK6_ST	Q9Y6Q9	NCOA3	Q16659	MAPK6	T663	S669C	669	Missense	distal	6	no	2.516	2.485	EPSD	TCGA;ICGC;COSMIC	2.026	Down-regulation
CMGC_MAPK_ERK3_MAPK6_ST	Q9Y6Q9	NCOA3	Q16659	MAPK6	S664	S662C	662	Missense	proximal	-2	no	2.208	2.218	EPSD	TCGA;COSMIC	2.026	Up-regulation
CMGC_MAPK_ERK3_MAPK6_ST	Q9Y6Q9	NCOA3	Q16659	MAPK6	S664	S671C	671	Missense	distal	7	no	2.208	2.210	EPSD	TCGA;COSMIC	2.026	Up-regulation
CMGC_MAPK_ERK3_MAPK6_ST	Q9Y6Q9	NCOA3	Q16659	MAPK6	S664	S669C	669	Missense	distal	5	no	2.208	2.077	EPSD	TCGA;ICGC;COSMIC	2.026	Down-regulation
CMGC_MAPK_ERK3_MAPK6_ST	Q9Y6Q9	NCOA3	Q16659	MAPK6	T706	D709Y	709	Missense	distal	3	no	2.380	2.375	EPSD	TCGA;COSMIC	2.026	Down-regulation
CMGC_MAPK_ERK3_MAPK6_ST	Q9Y6Q9	NCOA3	Q16659	MAPK6	T773	I774S	774	Missense	proximal	1	no	2.240	2.245	EPSD	TCGA;ICGC;COSMIC	2.026	Up-regulation
CMGC_MAPK_ERK3_MAPK6_ST	Q9Y6Q9	NCOA3	Q16659	MAPK6	S836	S841T	841	Missense	distal	5	no	1.767	2.510	EPSD	TCGA;ICGC;COSMIC	2.026	Gain
CMGC_MAPK_ERK3_MAPK6_ST	Q9Y6Q9	NCOA3	Q16659	MAPK6	T947	P941T	941	Missense	distal	-6	no	2.435	2.491	EPSD	TCGA	2.026	Up-regulation
CMGC_MAPK_ERK3_MAPK6_ST	Q9Y6Q9	NCOA3	Q16659	MAPK6	T947	R940I	940	Missense	distal	-7	no	2.435	2.385	EPSD	TCGA;COSMIC	2.026	Down-regulation
CMGC_MAPK_ERK3_MAPK6_ST	O95551	TDP2	Q16659	MAPK6	S60	V66M	66	Missense	distal	6	no	6.710	6.698	PhosphoSitePlus	TCGA;COSMIC	2.026	Down-regulation
CMGC_MAPK_ERK3_MAPK6_ST	O95551	TDP2	Q16659	MAPK6	S60	E53A	53	Missense	distal	-7	no	6.710	6.690	PhosphoSitePlus	TCGA;COSMIC	2.026	Down-regulation
CMGC_MAPK_ERK3_MAPK6_ST	O95551	TDP2	Q16659	MAPK6	S60	N59S	59	Missense	proximal	-1	no	6.710	6.727	PhosphoSitePlus	TCGA;COSMIC	2.026	Up-regulation
CMGC_MAPK_ERK3_MAPK6_ST	O95551	TDP2	Q16659	MAPK6	T92	E91A	91	Missense	proximal	-1	no	2.827	2.950	EPSD	TCGA;ICGC;COSMIC	2.026	Up-regulation
CAMK_CAMK2_CAMK2G_ST	Q13555	CAMK2G	Q13555	CAMK2G	S280	R275Q	275	Missense	distal	-5	no	6.076	6.245	EPSD;PhosphoSitePlus	TCGA;ICGC	2.962	Up-regulation
CAMK_CAMK2_CAMK2G_ST	Q13555	CAMK2G	Q13555	CAMK2G	T287	F294L	294	Missense	distal	7	no	6.560	6.544	EPSD	TCGA;COSMIC;CCLE	2.962	Down-regulation
CAMK_CAMK2_CAMK2G_ST	Q13555	CAMK2G	Q13555	CAMK2G	T287	R292H	292	Missense	distal	5	no	6.560	5.574	EPSD	TCGA;ICGC	2.962	Down-regulation
CAMK_CAMK2_CAMK2G_ST	Q13555	CAMK2G	Q13555	CAMK2G	S319	S325L	325	Missense	distal	6	no	7.009	6.279	PhosphoSitePlus;EPSD	TCGA;ICGC;COSMIC	2.962	Down-regulation
CAMK_CAMK2_CAMK2G_ST	Q13555	CAMK2G	Q13555	CAMK2G	S319	A317V	317	Missense	proximal	-2	no	7.009	6.974	PhosphoSitePlus;EPSD	TCGA;ICGC	2.962	Down-regulation
CAMK_CAMK2_CAMK2G_ST	Q13555	CAMK2G	Q13555	CAMK2G	S325	S325L	325	Missense	central	0	yes	3.511	0.000	EPSD	TCGA;ICGC;COSMIC	2.962	Loss
CAMK_CAMK2_CAMK2G_ST	P98082	DAB2	Q13555	CAMK2G	S310	S313C	313	Missense	distal	3	no	3.389	3.519	EPSD	TCGA;ICGC;COSMIC	2.962	Up-regulation
CAMK_CAMK2_CAMK2G_ST	P98082	DAB2	Q13555	CAMK2G	S310	S313Y	313	Missense	distal	3	no	3.389	3.476	EPSD	TCGA;ICGC;COSMIC	2.962	Up-regulation
CAMK_CAMK2_CAMK2G_ST	P98082	DAB2	Q13555	CAMK2G	S310	S313F	313	Missense	distal	3	no	3.389	3.364	EPSD	TCGA;ICGC;COSMIC	2.962	Down-regulation
CAMK_CAMK2_CAMK2G_ST	P98082	DAB2	Q13555	CAMK2G	S310	S316Y	316	Missense	distal	6	no	3.389	2.993	EPSD	TCGA;ICGC	2.962	Down-regulation
CAMK_CAMK2_CAMK2G_ST	P98082	DAB2	Q13555	CAMK2G	S313	S313C	313	Missense	central	0	yes	3.278	0.000	EPSD	TCGA;ICGC;COSMIC	2.962	Loss
CAMK_CAMK2_CAMK2G_ST	P98082	DAB2	Q13555	CAMK2G	S313	S313Y	313	Missense	central	0	yes	3.278	0.000	EPSD	TCGA;ICGC;COSMIC	2.962	Loss
CAMK_CAMK2_CAMK2G_ST	P98082	DAB2	Q13555	CAMK2G	S313	S313F	313	Missense	central	0	yes	3.278	0.000	EPSD	TCGA;ICGC;COSMIC	2.962	Loss
CAMK_CAMK2_CAMK2G_ST	P98082	DAB2	Q13555	CAMK2G	S313	S316Y	316	Missense	distal	3	no	3.278	3.365	EPSD	TCGA;ICGC	2.962	Up-regulation
CAMK_CAMK2_CAMK2G_ST	P98082	DAB2	Q13555	CAMK2G	T371	S369L	369	Missense	proximal	-2	no	2.898	3.039	EPSD	TCGA;ICGC;COSMIC	2.962	Gain
CAMK_CAMK2_CAMK2G_ST	P98082	DAB2	Q13555	CAMK2G	S456	V463I	463	Missense	distal	7	no	3.194	3.186	EPSD	TCGA;COSMIC;GDSC;CCLE	2.962	Down-regulation
CAMK_CAMK2_CAMK2G_ST	P98082	DAB2	Q13555	CAMK2G	S456	D452N	452	Missense	distal	-4	no	3.194	3.101	EPSD	TCGA;COSMIC	2.962	Down-regulation
CAMK_CAMK2_CAMK2G_ST	P98082	DAB2	Q13555	CAMK2G	S456	L454R	454	Missense	proximal	-2	no	3.194	3.201	EPSD	TCGA;COSMIC	2.962	Up-regulation
CAMK_CAMK2_CAMK2G_ST	P98082	DAB2	Q13555	CAMK2G	S723	P725R	725	Missense	proximal	2	no	6.673	6.656	PhosphoSitePlus	TCGA;COSMIC	2.962	Down-regulation
CAMK_CAMK2_CAMK2G_ST	P98082	DAB2	Q13555	CAMK2G	S723	S723F	723	Missense	central	0	yes	6.673	0.000	PhosphoSitePlus	TCGA;COSMIC;CCLE	2.962	Loss
CAMK_CAMK2_CAMK2G_ST	P98082	DAB2	Q13555	CAMK2G	S723	S723P	723	Missense	central	0	yes	6.673	0.000	PhosphoSitePlus	TCGA;COSMIC	2.962	Loss
CAMK_CAMK2_CAMK2G_ST	P98082	DAB2	Q13555	CAMK2G	T727	P725R	725	Missense	proximal	-2	no	3.822	3.872	EPSD	TCGA;COSMIC	2.962	Up-regulation
CAMK_CAMK2_CAMK2G_ST	P98082	DAB2	Q13555	CAMK2G	T727	S723F	723	Missense	distal	-4	no	3.822	3.823	EPSD	TCGA;COSMIC;CCLE	2.962	Up-regulation
CAMK_CAMK2_CAMK2G_ST	P98082	DAB2	Q13555	CAMK2G	T727	S723P	723	Missense	distal	-4	no	3.822	3.879	EPSD	TCGA;COSMIC	2.962	Up-regulation
CAMK_CAMK2_CAMK2G_ST	P98082	DAB2	Q13555	CAMK2G	S749	P755S	755	Missense	distal	6	no	2.635	3.064	EPSD	TCGA;COSMIC	2.962	Gain
CAMK_CAMK2_CAMK2G_ST	Q16625	OCLN	Q13555	CAMK2G	S159	V160A	160	Missense	proximal	1	no	3.044	2.934	EPSD	TCGA	2.962	Loss
CAMK_CAMK2_CAMK2G_ST	O95180	CACNA1H	Q13555	CAMK2G	S475	R474C	474	Missense	proximal	-1	no	3.189	2.981	EPSD	TCGA;ICGC;COSMIC	2.962	Down-regulation
CAMK_CAMK2_CAMK2G_ST	O95180	CACNA1H	Q13555	CAMK2G	S475	R469C	469	Missense	distal	-6	no	3.189	3.070	EPSD	TCGA;ICGC;COSMIC	2.962	Down-regulation
CAMK_CAMK2_CAMK2G_ST	O95180	CACNA1H	Q13555	CAMK2G	S484	R487C	487	Missense	distal	3	no	3.793	3.895	EPSD	TCGA;ICGC;COSMIC	2.962	Up-regulation
CAMK_CAMK2_CAMK2G_ST	O95180	CACNA1H	Q13555	CAMK2G	S558	S558L	558	Missense	central	0	yes	3.040	0.000	EPSD	TCGA;ICGC;COSMIC	2.962	Loss
CAMK_CAMK2_CAMK2G_ST	O95180	CACNA1H	Q13555	CAMK2G	S1107	D1112Y	1112	Missense	distal	5	no	3.048	2.785	EPSD	TCGA;ICGC;COSMIC	2.962	Loss
CAMK_CAMK2_CAMK2G_ST	O95180	CACNA1H	Q13555	CAMK2G	S1107	R1105C	1105	Missense	proximal	-2	no	3.048	2.920	EPSD	TCGA;ICGC;COSMIC	2.962	Loss
CAMK_CAMK2_CAMK2G_ST	O95180	CACNA1H	Q13555	CAMK2G	S1144	L1148P	1148	Missense	distal	4	no	3.703	3.678	EPSD	TCGA;ICGC;COSMIC	2.962	Down-regulation
CAMK_CAMK2_CAMK2G_ST	O95180	CACNA1H	Q13555	CAMK2G	T1806	V1804M	1804	Missense	proximal	-2	no	2.948	2.964	EPSD	TCGA;ICGC;COSMIC;GDSC	2.962	Gain
CAMK_CAMK2_CAMK2G_ST	O95180	CACNA1H	Q13555	CAMK2G	S2137	L2132R	2132	Missense	distal	-5	no	3.954	3.675	EPSD	TCGA;ICGC;COSMIC	2.962	Down-regulation
Atypical_PDHK_PDHK_PDK1_ST	P08559	PDHA1	Q15118	PDK1	S232	A236D	236	Missense	distal	4	no	0.299	0.257	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	0.124	Down-regulation
Atypical_PDHK_PDHK_PDK1_ST	P29803	PDHA2	Q15118	PDK1	S230	G228V	228	Missense	proximal	-2	no	0.332	0.325	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	0.124	Down-regulation
Atypical_PDHK_PDHK_PDK1_ST	P29803	PDHA2	Q15118	PDK1	S230	Y225F	225	Missense	distal	-5	no	0.332	0.339	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	0.124	Up-regulation
Atypical_PDHK_PDHK_PDK1_ST	P29803	PDHA2	Q15118	PDK1	S230	Y225C	225	Missense	distal	-5	no	0.332	0.331	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	0.124	Down-regulation
Atypical_PDHK_PDHK_PDK1_ST	P29803	PDHA2	Q15118	PDK1	S230	E232V	232	Missense	proximal	2	no	0.332	0.336	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	0.124	Up-regulation
Atypical_PDHK_PDHK_PDK1_ST	P29803	PDHA2	Q15118	PDK1	S230	G226R	226	Missense	distal	-4	no	0.332	0.324	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	0.124	Down-regulation
Atypical_PDHK_PDHK_PDK1_ST	P29803	PDHA2	Q15118	PDK1	S230	R233K	233	Missense	distal	3	no	0.332	0.336	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	0.124	Up-regulation
Atypical_PDHK_PDHK_PDK1_ST	P29803	PDHA2	Q15118	PDK1	T231	E232V	232	Missense	proximal	1	no	0.117	0.134	EPSD	TCGA;ICGC;COSMIC	0.124	Gain
Atypical_PDHK_PDHK_PDK1_ST	P29803	PDHA2	Q15118	PDK1	T231	G226R	226	Missense	distal	-5	no	0.117	0.133	EPSD	TCGA;ICGC;COSMIC	0.124	Gain
Atypical_PDHK_PDHK_PDK1_ST	P29803	PDHA2	Q15118	PDK1	S291	Y285H	285	Missense	distal	-6	no	0.357	0.354	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	0.124	Down-regulation
Atypical_PDHK_PDHK_PDK1_ST	P29803	PDHA2	Q15118	PDK1	S291	M292I	292	Missense	proximal	1	no	0.357	0.323	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	0.124	Down-regulation
Atypical_PDHK_PDHK_PDK1_ST	P29803	PDHA2	Q15118	PDK1	S291	S298C	298	Missense	distal	7	no	0.357	0.330	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	0.124	Down-regulation
Atypical_PDHK_PDHK_PDK1_ST	P29803	PDHA2	Q15118	PDK1	S291	S293T	293	Missense	proximal	2	no	0.357	0.355	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	0.124	Down-regulation
Atypical_PDHK_PDHK_PDK1_ST	P29803	PDHA2	Q15118	PDK1	S293	R300C	300	Missense	distal	7	no	0.147	0.156	EPSD	TCGA;ICGC;COSMIC	0.124	Up-regulation
Atypical_PDHK_PDHK_PDK1_ST	P29803	PDHA2	Q15118	PDK1	S293	R300H	300	Missense	distal	7	no	0.147	0.168	EPSD	TCGA;ICGC;COSMIC;CCLE	0.124	Up-regulation
Atypical_PDHK_PDHK_PDK1_ST	P29803	PDHA2	Q15118	PDK1	S293	M292I	292	Missense	proximal	-1	no	0.147	0.142	EPSD	TCGA;ICGC;COSMIC	0.124	Down-regulation
Atypical_PDHK_PDHK_PDK1_ST	P29803	PDHA2	Q15118	PDK1	S293	R300S	300	Missense	distal	7	no	0.147	0.184	EPSD	TCGA;ICGC;COSMIC	0.124	Up-regulation
Atypical_PDHK_PDHK_PDK1_ST	P29803	PDHA2	Q15118	PDK1	S293	R300L	300	Missense	distal	7	no	0.147	0.150	EPSD	TCGA;ICGC;COSMIC	0.124	Up-regulation
Atypical_PDHK_PDHK_PDK1_ST	P29803	PDHA2	Q15118	PDK1	S298	R300C	300	Missense	proximal	2	no	0.318	0.329	PhosphoSitePlus;EPSD	TCGA;ICGC;COSMIC	0.124	Up-regulation
Atypical_PDHK_PDHK_PDK1_ST	P29803	PDHA2	Q15118	PDK1	S298	R302Q	302	Missense	distal	4	no	0.318	0.333	PhosphoSitePlus;EPSD	TCGA;ICGC;COSMIC	0.124	Up-regulation
Atypical_PDHK_PDHK_PDK1_ST	P29803	PDHA2	Q15118	PDK1	S298	R300H	300	Missense	proximal	2	no	0.318	0.323	PhosphoSitePlus;EPSD	TCGA;ICGC;COSMIC;CCLE	0.124	Up-regulation
Atypical_PDHK_PDHK_PDK1_ST	P29803	PDHA2	Q15118	PDK1	S298	M292I	292	Missense	distal	-6	no	0.318	0.316	PhosphoSitePlus;EPSD	TCGA;ICGC;COSMIC	0.124	Down-regulation
Atypical_PDHK_PDHK_PDK1_ST	P29803	PDHA2	Q15118	PDK1	S298	R300S	300	Missense	proximal	2	no	0.318	0.326	PhosphoSitePlus;EPSD	TCGA;ICGC;COSMIC	0.124	Up-regulation
Atypical_PDHK_PDHK_PDK1_ST	P29803	PDHA2	Q15118	PDK1	S298	R300L	300	Missense	proximal	2	no	0.318	0.322	PhosphoSitePlus;EPSD	TCGA;ICGC;COSMIC	0.124	Up-regulation
Atypical_PDHK_PDHK_PDK1_ST	P29803	PDHA2	Q15118	PDK1	S298	S298C	298	Missense	central	0	yes	0.318	0.000	PhosphoSitePlus;EPSD	TCGA;ICGC;COSMIC	0.124	Loss
Atypical_PDHK_PDHK_PDK1_ST	P29803	PDHA2	Q15118	PDK1	S298	S293T	293	Missense	distal	-5	no	0.318	0.329	PhosphoSitePlus;EPSD	TCGA;ICGC;COSMIC	0.124	Up-regulation
CMGC_MAPK_JNK_MAPK8_ST	Q96EB6	SIRT1	P45983	MAPK8	T177	R181W	181	Missense	distal	4	no	7.863	7.836	EPSD	TCGA;COSMIC;GDSC	2.638	Down-regulation
CMGC_MAPK_JNK_MAPK8_ST	Q96EB6	SIRT1	P45983	MAPK8	S540	R543I	543	Missense	distal	3	no	7.428	7.370	EPSD	TCGA;COSMIC	2.638	Down-regulation
CMGC_MAPK_JNK_MAPK8_ST	Q96EB6	SIRT1	P45983	MAPK8	S545	S549F	549	Missense	distal	4	no	6.659	6.201	EPSD	TCGA;COSMIC	2.638	Down-regulation
CMGC_MAPK_JNK_MAPK8_ST	Q96EB6	SIRT1	P45983	MAPK8	S545	R543I	543	Missense	proximal	-2	no	6.659	6.739	EPSD	TCGA;COSMIC	2.638	Up-regulation
CMGC_MAPK_JNK_MAPK8_ST	Q96EB6	SIRT1	P45983	MAPK8	S659	A655T	655	Missense	distal	-4	no	2.712	2.676	EPSD	TCGA;COSMIC	2.638	Down-regulation
CMGC_MAPK_JNK_MAPK8_ST	Q96EB6	SIRT1	P45983	MAPK8	S659	V665I	665	Missense	distal	6	no	2.712	2.758	EPSD	TCGA;COSMIC	2.638	Up-regulation
CMGC_MAPK_JNK_MAPK8_ST	Q96EB6	SIRT1	P45983	MAPK8	S682	Q681H	681	Missense	proximal	-1	no	7.387	7.371	EPSD	TCGA;COSMIC	2.638	Down-regulation
CMGC_MAPK_JNK_MAPK8_ST	Q96EB6	SIRT1	P45983	MAPK8	S682	S675N	675	Missense	distal	-7	no	7.387	7.401	EPSD	TCGA;COSMIC	2.638	Up-regulation
CMGC_MAPK_JNK_MAPK8_ST	P46937	YAP1	P45983	MAPK8	T119	Q121H	121	Missense	proximal	2	no	8.541	8.424	EPSD	TCGA;ICGC;COSMIC	2.638	Down-regulation
CMGC_MAPK_JNK_MAPK8_ST	P46937	YAP1	P45983	MAPK8	T119	R124P	124	Missense	distal	5	no	8.541	8.552	EPSD	TCGA;ICGC;COSMIC	2.638	Up-regulation
CMGC_MAPK_JNK_MAPK8_ST	P46937	YAP1	P45983	MAPK8	T119	R124Q	124	Missense	distal	5	no	8.541	8.489	EPSD	TCGA;ICGC;COSMIC	2.638	Down-regulation
CMGC_MAPK_JNK_MAPK8_ST	P46937	YAP1	P45983	MAPK8	S128	G135E	135	Missense	distal	7	no	8.498	8.433	EPSD	TCGA;ICGC;COSMIC	2.638	Down-regulation
CMGC_MAPK_JNK_MAPK8_ST	P46937	YAP1	P45983	MAPK8	S128	Q121H	121	Missense	distal	-7	no	8.498	8.505	EPSD	TCGA;ICGC;COSMIC	2.638	Up-regulation
CMGC_MAPK_JNK_MAPK8_ST	P46937	YAP1	P45983	MAPK8	S128	P129S	129	Missense	proximal	1	no	8.498	0.769	EPSD	TCGA;ICGC;COSMIC	2.638	Loss
CMGC_MAPK_JNK_MAPK8_ST	P46937	YAP1	P45983	MAPK8	S128	R124P	124	Missense	distal	-4	no	8.498	8.634	EPSD	TCGA;ICGC;COSMIC	2.638	Up-regulation
CMGC_MAPK_JNK_MAPK8_ST	P46937	YAP1	P45983	MAPK8	S128	R124Q	124	Missense	distal	-4	no	8.498	9.018	EPSD	TCGA;ICGC;COSMIC	2.638	Up-regulation
CMGC_MAPK_JNK_MAPK8_ST	P46937	YAP1	P45983	MAPK8	S138	G135E	135	Missense	distal	-3	no	7.515	7.848	EPSD	TCGA;ICGC;COSMIC	2.638	Up-regulation
CMGC_MAPK_JNK_MAPK8_ST	P46937	YAP1	P45983	MAPK8	S138	S138F	138	Missense	central	0	yes	7.515	0.000	EPSD	TCGA;ICGC;COSMIC	2.638	Loss
CMGC_MAPK_JNK_MAPK8_ST	P46937	YAP1	P45983	MAPK8	S138	G140E	140	Missense	proximal	2	no	7.515	7.780	EPSD	TCGA;ICGC	2.638	Up-regulation
CMGC_MAPK_JNK_MAPK8_ST	P46937	YAP1	P45983	MAPK8	T143	S138F	138	Missense	distal	-5	no	6.792	7.261	EPSD	TCGA;ICGC;COSMIC	2.638	Up-regulation
CMGC_MAPK_JNK_MAPK8_ST	P46937	YAP1	P45983	MAPK8	T143	G140E	140	Missense	distal	-3	no	6.792	7.125	EPSD	TCGA;ICGC	2.638	Up-regulation
CMGC_MAPK_JNK_MAPK8_ST	P46937	YAP1	P45983	MAPK8	T154	T154A	154	Missense	central	0	yes	7.506	0.000	PhosphoSitePlus;EPSD	TCGA;ICGC;COSMIC	2.638	Loss
CMGC_MAPK_JNK_MAPK8_ST	P46937	YAP1	P45983	MAPK8	T154	Q158H	158	Missense	distal	4	no	7.506	7.309	PhosphoSitePlus;EPSD	TCGA;ICGC;COSMIC	2.638	Down-regulation
CMGC_MAPK_JNK_MAPK8_ST	P46937	YAP1	P45983	MAPK8	S217	A214T	214	Missense	distal	-3	no	8.888	8.834	EPSD	TCGA;ICGC	2.638	Down-regulation
CMGC_MAPK_JNK_MAPK8_ST	P46937	YAP1	P45983	MAPK8	S340	P341A	341	Missense	proximal	1	no	11.219	4.871	EPSD	TCGA;ICGC;COSMIC	2.638	Down-regulation
CMGC_MAPK_JNK_MAPK8_ST	P46937	YAP1	P45983	MAPK8	S340	Q344K	344	Missense	distal	4	no	11.219	11.380	EPSD	TCGA;ICGC;COSMIC	2.638	Up-regulation
CMGC_MAPK_JNK_MAPK8_ST	P46937	YAP1	P45983	MAPK8	S340	I333N	333	Missense	distal	-7	no	11.219	11.225	EPSD	TCGA;ICGC;COSMIC	2.638	Up-regulation
CMGC_MAPK_JNK_MAPK8_ST	P46937	YAP1	P45983	MAPK8	S340	N339H	339	Missense	proximal	-1	no	11.219	11.227	EPSD	TCGA;ICGC;COSMIC	2.638	Up-regulation
CMGC_MAPK_JNK_MAPK8_ST	P46937	YAP1	P45983	MAPK8	S367	S366C	366	Missense	proximal	-1	no	6.322	6.303	EPSD	TCGA	2.638	Down-regulation
CMGC_MAPK_JNK_MAPK8_ST	P46937	YAP1	P45983	MAPK8	S367	G369R	369	Missense	proximal	2	no	6.322	6.282	EPSD	TCGA;ICGC	2.638	Down-regulation
CMGC_MAPK_JNK_MAPK8_ST	P46937	YAP1	P45983	MAPK8	S400	E396D	396	Missense	distal	-4	no	2.744	2.321	EPSD	TCGA;ICGC;COSMIC	2.638	Loss
CMGC_MAPK_JNK_MAPK8_ST	P46937	YAP1	P45983	MAPK8	T412	P413Q	413	Missense	proximal	1	no	7.555	0.445	EPSD	TCGA;ICGC;COSMIC	2.638	Loss
CMGC_MAPK_JNK_MAPK8_ST	P36956	SREBF1	P45983	MAPK8	T105	P106A	106	Missense	proximal	1	no	5.927	-0.420	EPSD	TCGA;COSMIC	2.638	Loss
CMGC_MAPK_JNK_MAPK8_ST	P36956	SREBF1	P45983	MAPK8	T105	S98P	98	Missense	distal	-7	no	5.927	5.933	EPSD	TCGA;COSMIC	2.638	Up-regulation
CMGC_MAPK_JNK_MAPK8_ST	P36956	SREBF1	P45983	MAPK8	S112	P106A	106	Missense	distal	-6	no	2.866	2.780	EPSD	TCGA;COSMIC	2.638	Down-regulation
CMGC_MAPK_JNK_MAPK8_ST	P36956	SREBF1	P45983	MAPK8	S112	F116S	116	Missense	distal	4	no	2.866	3.325	EPSD	TCGA;COSMIC	2.638	Up-regulation
CMGC_MAPK_JNK_MAPK8_ST	P36956	SREBF1	P45983	MAPK8	S117	F116S	116	Missense	proximal	-1	no	8.727	8.756	EPSD;PhosphoSitePlus	TCGA;COSMIC	2.638	Up-regulation
CMGC_MAPK_JNK_MAPK8_ST	P36956	SREBF1	P45983	MAPK8	T426	T419I	419	Missense	distal	-7	no	8.292	8.299	EPSD	TCGA;COSMIC	2.638	Up-regulation
CMGC_MAPK_JNK_MAPK8_ST	P36956	SREBF1	P45983	MAPK8	T426	V421A	421	Missense	distal	-5	no	8.292	7.751	EPSD	TCGA	2.638	Down-regulation
CMGC_MAPK_JNK_MAPK8_ST	P36956	SREBF1	P45983	MAPK8	S461	P459L	459	Missense	proximal	-2	no	8.677	8.484	EPSD	TCGA	2.638	Down-regulation
CMGC_MAPK_JNK_MAPK8_ST	P10636	MAPT	P45983	MAPK8	S46	T52I	52	Missense	distal	6	no	6.230	6.200	EPSD	TCGA;ICGC;COSMIC	2.638	Down-regulation
CMGC_MAPK_JNK_MAPK8_ST	P10636	MAPT	P45983	MAPK8	S46	P47S	47	Missense	proximal	1	no	6.230	-1.498	EPSD	TCGA;ICGC;COSMIC	2.638	Loss
CMGC_MAPK_JNK_MAPK8_ST	P10636	MAPT	P45983	MAPK8	S46	P47L	47	Missense	proximal	1	no	6.230	-1.342	EPSD	TCGA;ICGC;COSMIC	2.638	Loss
CMGC_MAPK_JNK_MAPK8_ST	P10636	MAPT	P45983	MAPK8	S46	G42C	42	Missense	distal	-4	no	6.230	6.351	EPSD	TCGA;ICGC;COSMIC	2.638	Up-regulation
CMGC_MAPK_JNK_MAPK8_ST	P10636	MAPT	P45983	MAPK8	T50	D54E	54	Missense	distal	4	no	8.886	9.037	EPSD	TCGA;ICGC;COSMIC	2.638	Up-regulation
CMGC_MAPK_JNK_MAPK8_ST	P10636	MAPT	P45983	MAPK8	T50	T52I	52	Missense	proximal	2	no	8.886	8.760	EPSD	TCGA;ICGC;COSMIC	2.638	Down-regulation
CMGC_MAPK_JNK_MAPK8_ST	P10636	MAPT	P45983	MAPK8	T50	P47S	47	Missense	distal	-3	no	8.886	9.048	EPSD	TCGA;ICGC;COSMIC	2.638	Up-regulation
CMGC_MAPK_JNK_MAPK8_ST	P10636	MAPT	P45983	MAPK8	T50	P47L	47	Missense	distal	-3	no	8.886	8.707	EPSD	TCGA;ICGC;COSMIC	2.638	Down-regulation
CMGC_MAPK_JNK_MAPK8_ST	P10636	MAPT	P45983	MAPK8	T50	G55R	55	Missense	distal	5	no	8.886	8.889	EPSD	TCGA;ICGC;COSMIC	2.638	Up-regulation
CMGC_MAPK_JNK_MAPK8_ST	P10636	MAPT	P45983	MAPK8	S64	G60S	60	Missense	distal	-4	no	1.839	2.728	EPSD	TCGA;ICGC;COSMIC	2.638	Gain
CMGC_MAPK_JNK_MAPK8_ST	P10636	MAPT	P45983	MAPK8	T69	A72V	72	Missense	distal	3	no	8.525	8.753	EPSD	TCGA;ICGC;COSMIC	2.638	Up-regulation
CMGC_MAPK_JNK_MAPK8_ST	P10636	MAPT	P45983	MAPK8	T69	A66S	66	Missense	distal	-3	no	8.525	8.490	EPSD	TCGA;ICGC;COSMIC	2.638	Down-regulation
CMGC_MAPK_JNK_MAPK8_ST	P10636	MAPT	P45983	MAPK8	T111	E117K	117	Missense	distal	6	no	7.410	7.427	EPSD	TCGA;ICGC;COSMIC	2.638	Up-regulation
CMGC_MAPK_JNK_MAPK8_ST	P10636	MAPT	P45983	MAPK8	T111	A118V	118	Missense	distal	7	no	7.410	7.490	EPSD	TCGA;ICGC;COSMIC	2.638	Up-regulation
CMGC_MAPK_JNK_MAPK8_ST	P10636	MAPT	P45983	MAPK8	S228	S232Y	232	Missense	distal	4	no	9.293	8.768	EPSD	TCGA;ICGC;COSMIC	2.638	Down-regulation
CMGC_MAPK_JNK_MAPK8_ST	P10636	MAPT	P45983	MAPK8	S228	D223Y	223	Missense	distal	-5	no	9.293	9.669	EPSD	TCGA;ICGC;COSMIC	2.638	Up-regulation
CMGC_MAPK_JNK_MAPK8_ST	P10636	MAPT	P45983	MAPK8	S228	S227F	227	Missense	proximal	-1	no	9.293	9.264	EPSD	TCGA;ICGC;COSMIC	2.638	Down-regulation
CMGC_MAPK_JNK_MAPK8_ST	P10636	MAPT	P45983	MAPK8	S228	P234L	234	Missense	distal	6	no	9.293	9.246	EPSD	TCGA;ICGC;COSMIC	2.638	Down-regulation
CMGC_MAPK_JNK_MAPK8_ST	P10636	MAPT	P45983	MAPK8	S232	S232Y	232	Missense	central	0	yes	7.907	0.000	EPSD	TCGA;ICGC;COSMIC	2.638	Loss
CMGC_MAPK_JNK_MAPK8_ST	P10636	MAPT	P45983	MAPK8	S232	S227F	227	Missense	distal	-5	no	7.907	8.376	EPSD	TCGA;ICGC;COSMIC	2.638	Up-regulation
CMGC_MAPK_JNK_MAPK8_ST	P10636	MAPT	P45983	MAPK8	S232	P234L	234	Missense	proximal	2	no	7.907	7.830	EPSD	TCGA;ICGC;COSMIC	2.638	Down-regulation
CMGC_MAPK_JNK_MAPK8_ST	P10636	MAPT	P45983	MAPK8	S238	S232Y	232	Missense	distal	-6	no	7.548	7.780	EPSD	TCGA;ICGC;COSMIC	2.638	Up-regulation
CMGC_MAPK_JNK_MAPK8_ST	P10636	MAPT	P45983	MAPK8	S238	A240T	240	Missense	proximal	2	no	7.548	7.527	EPSD	TCGA;ICGC;COSMIC	2.638	Down-regulation
CMGC_MAPK_JNK_MAPK8_ST	P10636	MAPT	P45983	MAPK8	S238	P234L	234	Missense	distal	-4	no	7.548	7.221	EPSD	TCGA;ICGC;COSMIC	2.638	Down-regulation
CMGC_MAPK_JNK_MAPK8_ST	P10636	MAPT	P45983	MAPK8	S238	R244Q	244	Missense	distal	6	no	7.548	7.594	EPSD	TCGA;ICGC;COSMIC	2.638	Up-regulation
CMGC_MAPK_JNK_MAPK8_ST	P10636	MAPT	P45983	MAPK8	T248	R244Q	244	Missense	distal	-4	no	2.205	2.725	EPSD	TCGA;ICGC;COSMIC	2.638	Gain
CMGC_MAPK_JNK_MAPK8_ST	P10636	MAPT	P45983	MAPK8	S411	P415L	415	Missense	distal	4	no	7.541	7.134	EPSD	TCGA;ICGC;COSMIC	2.638	Down-regulation
CMGC_MAPK_JNK_MAPK8_ST	P10636	MAPT	P45983	MAPK8	T416	P415L	415	Missense	proximal	-1	no	8.962	8.943	EPSD	TCGA;ICGC;COSMIC	2.638	Down-regulation
CMGC_MAPK_JNK_MAPK8_ST	P10636	MAPT	P45983	MAPK8	S428	A430S	430	Missense	proximal	2	no	7.318	7.294	EPSD	TCGA;ICGC;COSMIC	2.638	Down-regulation
CMGC_MAPK_JNK_MAPK8_ST	P10636	MAPT	P45983	MAPK8	S428	V431L	431	Missense	distal	3	no	7.318	7.300	EPSD	TCGA;ICGC;COSMIC	2.638	Down-regulation
CMGC_MAPK_JNK_MAPK8_ST	P10636	MAPT	P45983	MAPK8	S428	A430V	430	Missense	proximal	2	no	7.318	7.000	EPSD	TCGA;ICGC;COSMIC	2.638	Down-regulation
CMGC_MAPK_JNK_MAPK8_ST	P10636	MAPT	P45983	MAPK8	S438	P436T	436	Missense	proximal	-2	no	9.810	9.730	EPSD	TCGA;ICGC;COSMIC	2.638	Down-regulation
CMGC_MAPK_JNK_MAPK8_ST	P10636	MAPT	P45983	MAPK8	S438	P436L	436	Missense	proximal	-2	no	9.810	9.617	EPSD	TCGA;ICGC;COSMIC	2.638	Down-regulation
CMGC_MAPK_JNK_MAPK8_ST	P10636	MAPT	P45983	MAPK8	S438	K440E	440	Missense	proximal	2	no	9.810	9.792	EPSD	TCGA;ICGC;COSMIC	2.638	Down-regulation
CMGC_MAPK_JNK_MAPK8_ST	P10636	MAPT	P45983	MAPK8	S438	S443F	443	Missense	distal	5	no	9.810	9.886	EPSD	TCGA;ICGC;COSMIC	2.638	Up-regulation
CMGC_MAPK_JNK_MAPK8_ST	P10636	MAPT	P45983	MAPK8	S438	V431L	431	Missense	distal	-7	no	9.810	9.809	EPSD	TCGA;ICGC;COSMIC	2.638	Down-regulation
CMGC_MAPK_JNK_MAPK8_ST	P10636	MAPT	P45983	MAPK8	S438	S444F	444	Missense	distal	6	no	9.810	9.742	EPSD	TCGA;ICGC	2.638	Down-regulation
CMGC_MAPK_JNK_MAPK8_ST	P10636	MAPT	P45983	MAPK8	S447	K440E	440	Missense	distal	-7	no	3.231	3.235	EPSD	TCGA;ICGC;COSMIC	2.638	Up-regulation
CMGC_MAPK_JNK_MAPK8_ST	P10636	MAPT	P45983	MAPK8	S447	S452C	452	Missense	distal	5	no	3.231	3.285	EPSD	TCGA;ICGC;COSMIC	2.638	Up-regulation
CMGC_MAPK_JNK_MAPK8_ST	P10636	MAPT	P45983	MAPK8	S447	S443F	443	Missense	distal	-4	no	3.231	2.294	EPSD	TCGA;ICGC;COSMIC	2.638	Loss
CMGC_MAPK_JNK_MAPK8_ST	P10636	MAPT	P45983	MAPK8	S447	S444F	444	Missense	distal	-3	no	3.231	2.858	EPSD	TCGA;ICGC	2.638	Down-regulation
CMGC_MAPK_JNK_MAPK8_ST	P10636	MAPT	P45983	MAPK8	S447	S452Y	452	Missense	distal	5	no	3.231	3.339	EPSD	TCGA;ICGC;COSMIC	2.638	Up-regulation
CMGC_MAPK_JNK_MAPK8_ST	P10636	MAPT	P45983	MAPK8	T470	R472Q	472	Missense	proximal	2	no	7.835	8.010	EPSD	TCGA	2.638	Up-regulation
CMGC_MAPK_JNK_MAPK8_ST	P10636	MAPT	P45983	MAPK8	T470	R472W	472	Missense	proximal	2	no	7.835	7.763	EPSD	TCGA;COSMIC	2.638	Down-regulation
CMGC_MAPK_JNK_MAPK8_ST	P10636	MAPT	P45983	MAPK8	T492	A485T	485	Missense	distal	-7	no	6.477	6.479	EPSD	TCGA;COSMIC;GDSC;CCLE	2.638	Up-regulation
CMGC_MAPK_JNK_MAPK8_ST	P10636	MAPT	P45983	MAPK8	T492	P493Q	493	Missense	proximal	1	no	6.477	-0.632	EPSD	TCGA;COSMIC	2.638	Loss
CMGC_MAPK_JNK_MAPK8_ST	P10636	MAPT	P45983	MAPK8	T498	P493Q	493	Missense	distal	-5	no	7.332	7.309	EPSD	TCGA;COSMIC	2.638	Down-regulation
CMGC_MAPK_JNK_MAPK8_ST	P17275	JUNB	P45983	MAPK8	S74	S67N	67	Missense	distal	-7	no	2.706	2.721	EPSD	TCGA;ICGC;COSMIC	2.638	Up-regulation
CMGC_MAPK_JNK_MAPK8_ST	P17275	JUNB	P45983	MAPK8	S74	Y68H	68	Missense	distal	-6	no	2.706	2.607	EPSD	TCGA;ICGC;COSMIC	2.638	Loss
CMGC_MAPK_JNK_MAPK8_ST	Q9NRA8	EIF4ENIF1	P45983	MAPK8	S78	R76W	76	Missense	proximal	-2	no	7.112	7.118	EPSD	TCGA;ICGC;COSMIC	2.638	Up-regulation
CMGC_MAPK_JNK_MAPK8_ST	Q9NRA8	EIF4ENIF1	P45983	MAPK8	S115	L114F	114	Missense	proximal	-1	no	7.116	7.115	EPSD	TCGA;ICGC;COSMIC	2.638	Down-regulation
CMGC_MAPK_JNK_MAPK8_ST	Q9NRA8	EIF4ENIF1	P45983	MAPK8	S138	R134Q	134	Missense	distal	-4	no	6.232	6.752	EPSD	TCGA;ICGC;COSMIC	2.638	Up-regulation
CMGC_MAPK_JNK_MAPK8_ST	Q9NRA8	EIF4ENIF1	P45983	MAPK8	S301	D306N	306	Missense	distal	5	no	9.158	9.181	EPSD;PhosphoSitePlus	TCGA;COSMIC	2.638	Up-regulation
CMGC_MAPK_JNK_MAPK8_ST	Q9NRA8	EIF4ENIF1	P45983	MAPK8	S301	D304N	304	Missense	distal	3	no	9.158	9.242	EPSD;PhosphoSitePlus	TCGA;COSMIC	2.638	Up-regulation
CMGC_MAPK_JNK_MAPK8_ST	Q9NRA8	EIF4ENIF1	P45983	MAPK8	S301	P298L	298	Missense	distal	-3	no	9.158	8.979	EPSD;PhosphoSitePlus	TCGA;COSMIC	2.638	Down-regulation
CMGC_MAPK_JNK_MAPK8_ST	Q9NRA8	EIF4ENIF1	P45983	MAPK8	S333	S333C	333	Missense	central	0	yes	3.353	0.000	EPSD	TCGA;COSMIC	2.638	Loss
CMGC_MAPK_JNK_MAPK8_ST	Q9NRA8	EIF4ENIF1	P45983	MAPK8	S333	R336Q	336	Missense	distal	3	no	3.353	3.227	EPSD	TCGA;COSMIC	2.638	Down-regulation
CMGC_MAPK_JNK_MAPK8_ST	Q9NRA8	EIF4ENIF1	P45983	MAPK8	S333	V326F	326	Missense	distal	-7	no	3.353	3.350	EPSD	TCGA;COSMIC	2.638	Down-regulation
CMGC_MAPK_JNK_MAPK8_ST	Q9NRA8	EIF4ENIF1	P45983	MAPK8	T357	R350Q	350	Missense	distal	-7	no	7.279	7.270	EPSD	TCGA;COSMIC	2.638	Down-regulation
CMGC_MAPK_JNK_MAPK8_ST	Q9NRA8	EIF4ENIF1	P45983	MAPK8	S374	Q377E	377	Missense	distal	3	no	6.958	6.914	EPSD;PhosphoSitePlus	TCGA;COSMIC	2.638	Down-regulation
CMGC_MAPK_JNK_MAPK8_ST	Q9NRA8	EIF4ENIF1	P45983	MAPK8	S374	P375S	375	Missense	proximal	1	no	6.958	-0.771	EPSD;PhosphoSitePlus	TCGA;COSMIC	2.638	Loss
CMGC_MAPK_JNK_MAPK8_ST	Q9NRA8	EIF4ENIF1	P45983	MAPK8	S374	S374C	374	Missense	central	0	yes	6.958	0.000	EPSD;PhosphoSitePlus	TCGA	2.638	Loss
CMGC_MAPK_JNK_MAPK8_ST	Q9NRA8	EIF4ENIF1	P45983	MAPK8	S513	E516D	516	Missense	distal	3	no	9.189	9.297	PhosphoSitePlus;EPSD	TCGA;COSMIC	2.638	Up-regulation
CMGC_MAPK_JNK_MAPK8_ST	Q9NRA8	EIF4ENIF1	P45983	MAPK8	S513	H510N	510	Missense	distal	-3	no	9.189	9.104	PhosphoSitePlus;EPSD	TCGA;COSMIC	2.638	Down-regulation
CMGC_MAPK_JNK_MAPK8_ST	Q9NRA8	EIF4ENIF1	P45983	MAPK8	S611	P609H	609	Missense	proximal	-2	no	8.914	8.730	EPSD	TCGA	2.638	Down-regulation
CMGC_MAPK_JNK_MAPK8_ST	Q9NRA8	EIF4ENIF1	P45983	MAPK8	S611	A615T	615	Missense	distal	4	no	8.914	8.865	EPSD	TCGA	2.638	Down-regulation
CMGC_MAPK_JNK_MAPK8_ST	Q9NRA8	EIF4ENIF1	P45983	MAPK8	S687	L692I	692	Missense	distal	5	no	2.887	2.854	EPSD	TCGA	2.638	Down-regulation
CMGC_MAPK_JNK_MAPK8_ST	Q9NRA8	EIF4ENIF1	P45983	MAPK8	S693	L692I	692	Missense	proximal	-1	no	8.039	8.055	EPSD;PhosphoSitePlus	TCGA	2.638	Up-regulation
CMGC_MAPK_JNK_MAPK8_ST	Q9NRA8	EIF4ENIF1	P45983	MAPK8	T697	R703H	703	Missense	distal	6	no	6.708	6.720	EPSD	TCGA;COSMIC	2.638	Up-regulation
CMGC_MAPK_JNK_MAPK8_ST	Q9NRA8	EIF4ENIF1	P45983	MAPK8	T697	L692I	692	Missense	distal	-5	no	6.708	6.440	EPSD	TCGA	2.638	Down-regulation
CMGC_MAPK_JNK_MAPK8_ST	Q9NRA8	EIF4ENIF1	P45983	MAPK8	T697	R703C	703	Missense	distal	6	no	6.708	6.720	EPSD	TCGA;COSMIC	2.638	Up-regulation
CMGC_MAPK_JNK_MAPK8_ST	Q9NRA8	EIF4ENIF1	P45983	MAPK8	S746	A747V	747	Missense	proximal	1	no	3.118	0.721	EPSD	TCGA;COSMIC	2.638	Loss
CMGC_MAPK_JNK_MAPK8_ST	Q9NRA8	EIF4ENIF1	P45983	MAPK8	S746	S752F	752	Missense	distal	6	no	3.118	3.049	EPSD	TCGA;COSMIC	2.638	Down-regulation
CMGC_MAPK_JNK_MAPK8_ST	Q9NRA8	EIF4ENIF1	P45983	MAPK8	S752	S757Y	757	Missense	distal	5	no	9.877	9.985	EPSD;PhosphoSitePlus	TCGA;COSMIC	2.638	Up-regulation
CMGC_MAPK_JNK_MAPK8_ST	Q9NRA8	EIF4ENIF1	P45983	MAPK8	S752	A747V	747	Missense	distal	-5	no	9.877	10.418	EPSD;PhosphoSitePlus	TCGA;COSMIC	2.638	Up-regulation
CMGC_MAPK_JNK_MAPK8_ST	Q9NRA8	EIF4ENIF1	P45983	MAPK8	S752	T754I	754	Missense	proximal	2	no	9.877	9.751	EPSD;PhosphoSitePlus	TCGA	2.638	Down-regulation
CMGC_MAPK_JNK_MAPK8_ST	Q9NRA8	EIF4ENIF1	P45983	MAPK8	S752	S752F	752	Missense	central	0	yes	9.877	0.000	EPSD;PhosphoSitePlus	TCGA;COSMIC	2.638	Loss
CMGC_MAPK_JNK_MAPK8_ST	Q9NRA8	EIF4ENIF1	P45983	MAPK8	S760	S757Y	757	Missense	distal	-3	no	3.135	2.651	EPSD	TCGA;COSMIC	2.638	Down-regulation
CMGC_MAPK_JNK_MAPK8_ST	Q9NRA8	EIF4ENIF1	P45983	MAPK8	S760	S766L	766	Missense	distal	6	no	3.135	3.064	EPSD	TCGA;COSMIC	2.638	Down-regulation
CMGC_MAPK_JNK_MAPK8_ST	Q9NRA8	EIF4ENIF1	P45983	MAPK8	S760	T754I	754	Missense	distal	-6	no	3.135	3.203	EPSD	TCGA	2.638	Up-regulation
CMGC_MAPK_JNK_MAPK8_ST	Q9NRA8	EIF4ENIF1	P45983	MAPK8	T769	S766L	766	Missense	distal	-3	no	7.541	7.199	EPSD	TCGA;COSMIC	2.638	Down-regulation
CMGC_MAPK_JNK_MAPK8_ST	Q9NRA8	EIF4ENIF1	P45983	MAPK8	T769	R776H	776	Missense	distal	7	no	7.541	7.530	EPSD	TCGA;COSMIC	2.638	Down-regulation
CMGC_MAPK_JNK_MAPK8_ST	Q9NRA8	EIF4ENIF1	P45983	MAPK8	T769	R776C	776	Missense	distal	7	no	7.541	7.530	EPSD	TCGA;COSMIC	2.638	Down-regulation
CMGC_MAPK_JNK_MAPK8_ST	Q9NRA8	EIF4ENIF1	P45983	MAPK8	T792	A796T	796	Missense	distal	4	no	8.521	8.473	EPSD	TCGA;COSMIC	2.638	Down-regulation
CMGC_MAPK_JNK_MAPK8_ST	Q9NRA8	EIF4ENIF1	P45983	MAPK8	T802	R806H	806	Missense	distal	4	no	6.224	6.261	EPSD	TCGA;COSMIC	2.638	Up-regulation
CMGC_MAPK_JNK_MAPK8_ST	Q9NRA8	EIF4ENIF1	P45983	MAPK8	T802	A796T	796	Missense	distal	-6	no	6.224	6.246	EPSD	TCGA;COSMIC	2.638	Up-regulation
CMGC_MAPK_JNK_MAPK8_ST	Q9NRA8	EIF4ENIF1	P45983	MAPK8	T802	L805I	805	Missense	distal	3	no	6.224	6.121	EPSD	TCGA;COSMIC	2.638	Down-regulation
CMGC_MAPK_JNK_MAPK8_ST	Q9NRA8	EIF4ENIF1	P45983	MAPK8	T924	P929L	929	Missense	distal	5	no	8.601	8.599	EPSD	TCGA	2.638	Down-regulation
CMGC_MAPK_JNK_MAPK8_ST	Q9NRA8	EIF4ENIF1	P45983	MAPK8	S951	R944C	944	Missense	distal	-7	no	7.297	7.295	EPSD	TCGA;COSMIC	2.638	Down-regulation
CMGC_MAPK_JNK_MAPK8_ST	Q05639	EEF1A2	P45983	MAPK8	T22	G25S	25	Missense	distal	3	no	3.146	2.956	EPSD	TCGA;ICGC	2.638	Down-regulation
CMGC_MAPK_JNK_MAPK8_ST	Q05639	EEF1A2	P45983	MAPK8	S205	G198V	198	Missense	distal	-7	no	7.665	7.670	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	2.638	Up-regulation
CMGC_MAPK_JNK_MAPK8_ST	Q05639	EEF1A2	P45983	MAPK8	S358	V360A	360	Missense	proximal	2	no	8.216	8.534	PhosphoSitePlus;EPSD	TCGA;ICGC;COSMIC	2.638	Up-regulation
CMGC_MAPK_JNK_MAPK8_ST	Q05639	EEF1A2	P45983	MAPK8	S358	P359L	359	Missense	proximal	1	no	8.216	0.643	PhosphoSitePlus;EPSD	TCGA;ICGC;COSMIC	2.638	Loss
CMGC_MAPK_JNK_MAPK8_ST	Q05639	EEF1A2	P45983	MAPK8	S358	A355T	355	Missense	distal	-3	no	8.216	8.162	PhosphoSitePlus;EPSD	TCGA;ICGC;COSMIC	2.638	Down-regulation
CMGC_MAPK_JNK_MAPK8_ST	Q9H211	CDT1	P45983	MAPK8	S93	K100N	100	Missense	distal	7	no	7.852	7.936	EPSD	TCGA;ICGC;COSMIC	2.638	Up-regulation
CMGC_MAPK_JNK_MAPK8_ST	Q9H211	CDT1	P45983	MAPK8	S93	P94L	94	Missense	proximal	1	no	7.852	0.280	EPSD	TCGA;ICGC;COSMIC	2.638	Loss
CMGC_MAPK_JNK_MAPK8_ST	Q9H211	CDT1	P45983	MAPK8	T102	K100N	100	Missense	proximal	-2	no	7.593	7.445	EPSD	TCGA;ICGC;COSMIC	2.638	Down-regulation
CMGC_MAPK_JNK_MAPK8_ST	Q9H211	CDT1	P45983	MAPK8	T102	A104T	104	Missense	proximal	2	no	7.593	7.572	EPSD	TCGA;ICGC;COSMIC	2.638	Down-regulation
CMGC_MAPK_JNK_MAPK8_ST	Q9H211	CDT1	P45983	MAPK8	T102	A105T	105	Missense	distal	3	no	7.593	7.603	EPSD	TCGA;ICGC;COSMIC	2.638	Up-regulation
CMGC_MAPK_JNK_MAPK8_ST	Q9H211	CDT1	P45983	MAPK8	T152	E156D	156	Missense	distal	4	no	7.438	7.286	EPSD	TCGA;ICGC	2.638	Down-regulation
CMGC_MAPK_JNK_MAPK8_ST	Q9H211	CDT1	P45983	MAPK8	T152	E156K	156	Missense	distal	4	no	7.438	7.518	EPSD	TCGA;ICGC;COSMIC	2.638	Up-regulation
CMGC_MAPK_JNK_MAPK8_ST	Q9H211	CDT1	P45983	MAPK8	T152	G157D	157	Missense	distal	5	no	7.438	7.416	EPSD	TCGA;ICGC	2.638	Down-regulation
CMGC_MAPK_JNK_MAPK8_ST	Q9H211	CDT1	P45983	MAPK8	T213	P214H	214	Missense	proximal	1	no	9.762	1.847	EPSD	TCGA;ICGC;COSMIC	2.638	Loss
CMGC_MAPK_JNK_MAPK8_ST	Q9H211	CDT1	P45983	MAPK8	T213	T213M	213	Missense	central	0	yes	9.762	0.000	EPSD	TCGA;ICGC;COSMIC	2.638	Loss
CMGC_MAPK_JNK_MAPK8_ST	Q9H211	CDT1	P45983	MAPK8	T213	E212K	212	Missense	proximal	-1	no	9.762	9.765	EPSD	TCGA;ICGC;COSMIC;GDSC;CCLE	2.638	Up-regulation
CMGC_MAPK_JNK_MAPK8_ST	Q9H211	CDT1	P45983	MAPK8	T213	N209S	209	Missense	distal	-4	no	9.762	10.636	EPSD	TCGA;ICGC;COSMIC	2.638	Up-regulation
CMGC_MAPK_JNK_MAPK8_ST	Q9H211	CDT1	P45983	MAPK8	S318	A312S	312	Missense	distal	-6	no	8.942	8.938	EPSD	TCGA;ICGC	2.638	Down-regulation
CMGC_MAPK_JNK_MAPK8_ST	Q9H211	CDT1	P45983	MAPK8	S372	R366Q	366	Missense	distal	-6	no	8.781	8.680	EPSD	TCGA;ICGC;COSMIC	2.638	Down-regulation
CMGC_MAPK_JNK_MAPK8_ST	Q9H211	CDT1	P45983	MAPK8	S372	P373L	373	Missense	proximal	1	no	8.781	1.209	EPSD	TCGA;ICGC	2.638	Loss
CMGC_MAPK_JNK_MAPK8_ST	Q9H211	CDT1	P45983	MAPK8	S391	S386F	386	Missense	distal	-5	no	7.295	7.763	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	2.638	Up-regulation
CMGC_MAPK_JNK_MAPK8_ST	Q9H211	CDT1	P45983	MAPK8	S391	R385H	385	Missense	distal	-6	no	7.295	7.273	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	2.638	Down-regulation
CMGC_MAPK_JNK_MAPK8_ST	Q9H211	CDT1	P45983	MAPK8	T402	P404A	404	Missense	proximal	2	no	8.894	9.104	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	2.638	Up-regulation
CMGC_MAPK_JNK_MAPK8_ST	Q9H211	CDT1	P45983	MAPK8	T402	A409T	409	Missense	distal	7	no	8.894	8.896	EPSD;PhosphoSitePlus	TCGA;ICGC	2.638	Up-regulation
CMGC_MAPK_JNK_MAPK8_ST	Q9H211	CDT1	P45983	MAPK8	T406	P404A	404	Missense	proximal	-2	no	7.981	7.931	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	2.638	Down-regulation
CMGC_MAPK_JNK_MAPK8_ST	Q9H211	CDT1	P45983	MAPK8	T406	A409T	409	Missense	distal	3	no	7.981	7.991	EPSD;PhosphoSitePlus	TCGA;ICGC	2.638	Up-regulation
CMGC_MAPK_JNK_MAPK8_ST	Q9H211	CDT1	P45983	MAPK8	S411	P404A	404	Missense	distal	-7	no	8.546	8.540	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	2.638	Down-regulation
CMGC_MAPK_JNK_MAPK8_ST	Q9H211	CDT1	P45983	MAPK8	S411	A409T	409	Missense	proximal	-2	no	8.546	8.516	EPSD;PhosphoSitePlus	TCGA;ICGC	2.638	Down-regulation
CMGC_MAPK_JNK_MAPK8_ST	P15336	ATF2	P45983	MAPK8	T69	P70S	70	Missense	proximal	1	no	8.052	0.324	PhosphoSitePlus;EPSD	TCGA;COSMIC	2.638	Loss
CMGC_MAPK_JNK_MAPK8_ST	P15336	ATF2	P45983	MAPK8	T71	P70S	70	Missense	proximal	-1	no	8.758	8.768	EPSD;PhosphoSitePlus	TCGA;COSMIC	2.638	Up-regulation
CMGC_MAPK_JNK_MAPK8_ST	P15336	ATF2	P45983	MAPK8	S90	E93Q	93	Missense	distal	3	no	8.111	8.155	EPSD;PhosphoSitePlus	TCGA;COSMIC	2.638	Up-regulation
CMGC_MAPK_JNK_MAPK8_ST	P15336	ATF2	P45983	MAPK8	S90	G83D	83	Missense	distal	-7	no	8.111	8.106	EPSD;PhosphoSitePlus	TCGA;COSMIC	2.638	Down-regulation
CMGC_MAPK_JNK_MAPK8_ST	P15336	ATF2	P45983	MAPK8	S112	T116A	116	Missense	distal	4	no	6.996	7.045	EPSD	TCGA;COSMIC	2.638	Up-regulation
CMGC_MAPK_JNK_MAPK8_ST	P15336	ATF2	P45983	MAPK8	S112	S112P	112	Missense	central	0	yes	6.996	0.000	EPSD	TCGA;COSMIC	2.638	Loss
CMGC_MAPK_JNK_MAPK8_ST	P15336	ATF2	P45983	MAPK8	T116	T116A	116	Missense	central	0	yes	8.713	0.000	EPSD	TCGA;COSMIC	2.638	Loss
CMGC_MAPK_JNK_MAPK8_ST	P15336	ATF2	P45983	MAPK8	T116	S112P	112	Missense	distal	-4	no	8.713	8.048	EPSD	TCGA;COSMIC	2.638	Down-regulation
CMGC_MAPK_JNK_MAPK8_ST	P15336	ATF2	P45983	MAPK8	S136	D135N	135	Missense	proximal	-1	no	8.636	8.622	EPSD	TCGA	2.638	Down-regulation
CMGC_MAPK_JNK_MAPK8_ST	P15336	ATF2	P45983	MAPK8	S136	S136N	136	Missense	central	0	yes	8.636	0.000	EPSD	TCGA	2.638	Loss
CMGC_MAPK_JNK_MAPK8_ST	P15336	ATF2	P45983	MAPK8	S266	G260E	260	Missense	distal	-6	no	7.697	7.539	EPSD	TCGA;COSMIC	2.638	Down-regulation
CMGC_MAPK_JNK_MAPK8_ST	P15336	ATF2	P45983	MAPK8	S266	P267S	267	Missense	proximal	1	no	7.697	-0.031	EPSD	TCGA;COSMIC	2.638	Loss
CMGC_MAPK_JNK_MAPK8_ST	P15336	ATF2	P45983	MAPK8	S266	G263C	263	Missense	distal	-3	no	7.697	7.723	EPSD	TCGA;COSMIC	2.638	Up-regulation
CMGC_MAPK_JNK_MAPK8_ST	P15336	ATF2	P45983	MAPK8	T325	P326S	326	Missense	proximal	1	no	7.959	0.230	EPSD	TCGA;COSMIC	2.638	Loss
CMGC_MAPK_JNK_MAPK8_ST	P15336	ATF2	P45983	MAPK8	T325	S321F	321	Missense	distal	-4	no	7.959	7.021	EPSD	TCGA;COSMIC	2.638	Down-regulation
CMGC_MAPK_JNK_MAPK8_ST	P15336	ATF2	P45983	MAPK8	S328	P326S	326	Missense	proximal	-2	no	8.292	8.186	EPSD	TCGA;COSMIC	2.638	Down-regulation
CMGC_MAPK_JNK_MAPK8_ST	P15336	ATF2	P45983	MAPK8	S328	P334A	334	Missense	distal	6	no	8.292	8.313	EPSD	TCGA;COSMIC	2.638	Up-regulation
CMGC_MAPK_JNK_MAPK8_ST	P15336	ATF2	P45983	MAPK8	S328	S321F	321	Missense	distal	-7	no	8.292	8.308	EPSD	TCGA;COSMIC	2.638	Up-regulation
CMGC_MAPK_JNK_MAPK8_ST	P15336	ATF2	P45983	MAPK8	T333	P326S	326	Missense	distal	-7	no	7.887	7.881	EPSD	TCGA;COSMIC	2.638	Down-regulation
CMGC_MAPK_JNK_MAPK8_ST	P15336	ATF2	P45983	MAPK8	T333	P334A	334	Missense	proximal	1	no	7.887	1.540	EPSD	TCGA;COSMIC	2.638	Loss
CMGC_MAPK_JNK_MAPK8_ST	P15336	ATF2	P45983	MAPK8	S446	Q453H	453	Missense	distal	7	no	7.654	7.689	EPSD	TCGA;COSMIC	2.638	Up-regulation
CMGC_MAPK_JNK_MAPK8_ST	P01106	MYC	P45983	MAPK8	T58	E54D	54	Missense	distal	-4	no	7.250	6.827	EPSD	TCGA;ICGC;COSMIC;GDSC	2.638	Down-regulation
CMGC_MAPK_JNK_MAPK8_ST	P01106	MYC	P45983	MAPK8	S161	S161L	161	Missense	central	0	yes	9.867	0.000	EPSD	TCGA;ICGC;COSMIC	2.638	Loss
CMGC_MAPK_JNK_MAPK8_ST	P01106	MYC	P45983	MAPK8	S204	S207L	207	Missense	distal	3	no	8.001	8.228	EPSD	TCGA;ICGC;COSMIC	2.638	Up-regulation
CMGC_MAPK_JNK_MAPK8_ST	P01106	MYC	P45983	MAPK8	S344	K341R	341	Missense	distal	-3	no	7.193	6.810	EPSD	TCGA;ICGC;COSMIC	2.638	Down-regulation
CMGC_MAPK_JNK_MAPK8_ST	P01106	MYC	P45983	MAPK8	S347	K341R	341	Missense	distal	-6	no	2.774	2.941	EPSD	TCGA;ICGC;COSMIC	2.638	Up-regulation
CMGC_MAPK_JNK_MAPK8_ST	P05067	APP	P45983	MAPK8	T381	E380K	380	Missense	proximal	-1	no	7.538	7.541	EPSD	TCGA;COSMIC;CCLE	2.638	Up-regulation
CMGC_MAPK_JNK_MAPK8_ST	P05067	APP	P45983	MAPK8	T743	R747P	747	Missense	distal	4	no	9.063	9.403	EPSD	TCGA;COSMIC	2.638	Up-regulation
CMGC_MAPK_JNK_MAPK8_ST	P05067	APP	P45983	MAPK8	T743	R747C	747	Missense	distal	4	no	9.063	9.096	EPSD	TCGA;COSMIC;GDSC	2.638	Up-regulation
CMGC_MAPK_JNK_MAPK8_ST	P05067	APP	P45983	MAPK8	T743	R747H	747	Missense	distal	4	no	9.063	9.100	EPSD	TCGA;COSMIC	2.638	Up-regulation
CMGC_MAPK_JNK_MAPK8_ST	O43524	FOXO3	P45983	MAPK8	S243	G241A	241	Missense	proximal	-2	no	2.522	2.642	EPSD	TCGA	2.638	Gain
CMGC_MAPK_JNK_MAPK8_ST	O43524	FOXO3	P45983	MAPK8	S243	G244A	244	Missense	proximal	1	no	2.522	3.112	EPSD	TCGA;ICGC;COSMIC	2.638	Gain
CMGC_MAPK_JNK_MAPK8_ST	O43524	FOXO3	P45983	MAPK8	S294	S299I	299	Missense	distal	5	no	8.470	8.518	EPSD	TCGA;ICGC;COSMIC	2.638	Up-regulation
CMGC_MAPK_JNK_MAPK8_ST	O43524	FOXO3	P45983	MAPK8	S294	R298C	298	Missense	distal	4	no	8.470	8.503	EPSD	TCGA;ICGC	2.638	Up-regulation
CMGC_MAPK_JNK_MAPK8_ST	O43524	FOXO3	P45983	MAPK8	S294	G293D	293	Missense	proximal	-1	no	8.470	8.480	EPSD	TCGA;ICGC;COSMIC	2.638	Up-regulation
CMGC_MAPK_JNK_MAPK8_ST	O43524	FOXO3	P45983	MAPK8	S297	G293D	293	Missense	distal	-4	no	2.391	2.713	EPSD	TCGA;ICGC;COSMIC	2.638	Gain
CMGC_MAPK_JNK_MAPK8_ST	O43524	FOXO3	P45983	MAPK8	S311	A305V	305	Missense	distal	-6	no	2.674	2.876	EPSD	TCGA;ICGC;COSMIC	2.638	Up-regulation
CMGC_MAPK_JNK_MAPK8_ST	O43524	FOXO3	P45983	MAPK8	S311	R310C	310	Missense	proximal	-1	no	2.674	2.681	EPSD	TCGA;ICGC;COSMIC	2.638	Up-regulation
CMGC_MAPK_JNK_MAPK8_ST	O43524	FOXO3	P45983	MAPK8	S311	D308Y	308	Missense	distal	-3	no	2.674	2.378	EPSD	TCGA;ICGC;COSMIC	2.638	Loss
CMGC_MAPK_JNK_MAPK8_ST	O43524	FOXO3	P45983	MAPK8	S311	S315F	315	Missense	distal	4	no	2.674	2.216	EPSD	TCGA;ICGC;COSMIC	2.638	Loss
CMGC_MAPK_JNK_MAPK8_ST	O43524	FOXO3	P45983	MAPK8	S311	R312C	312	Missense	proximal	1	no	2.674	2.232	EPSD	TCGA;ICGC;COSMIC	2.638	Loss
CMGC_MAPK_JNK_MAPK8_ST	O43524	FOXO3	P45983	MAPK8	S325	R323L	323	Missense	proximal	-2	no	8.338	8.328	EPSD	TCGA;ICGC;COSMIC	2.638	Down-regulation
CMGC_MAPK_JNK_MAPK8_ST	O43524	FOXO3	P45983	MAPK8	S325	M328I	328	Missense	distal	3	no	8.338	8.256	EPSD	TCGA;ICGC;COSMIC	2.638	Down-regulation
CMGC_MAPK_JNK_MAPK8_ST	O43524	FOXO3	P45983	MAPK8	S344	A341V	341	Missense	distal	-3	no	7.791	7.362	EPSD	TCGA;ICGC;COSMIC	2.638	Down-regulation
CMGC_MAPK_JNK_MAPK8_ST	O43524	FOXO3	P45983	MAPK8	S344	D340G	340	Missense	distal	-4	no	7.791	7.469	EPSD	TCGA;ICGC;COSMIC	2.638	Down-regulation
CMGC_MAPK_JNK_MAPK8_ST	O43524	FOXO3	P45983	MAPK8	S355	C362F	362	Missense	distal	7	no	8.320	8.343	EPSD	TCGA;ICGC;COSMIC	2.638	Up-regulation
CMGC_MAPK_JNK_MAPK8_ST	O43524	FOXO3	P45983	MAPK8	S402	P397S	397	Missense	distal	-5	no	7.290	7.178	EPSD	TCGA;ICGC;COSMIC	2.638	Down-regulation
CMGC_MAPK_JNK_MAPK8_ST	O43524	FOXO3	P45983	MAPK8	S402	P397L	397	Missense	distal	-5	no	7.290	7.650	EPSD	TCGA;ICGC;COSMIC	2.638	Up-regulation
CMGC_MAPK_JNK_MAPK8_ST	O43524	FOXO3	P45983	MAPK8	S402	S402L	402	Missense	central	0	yes	7.290	0.000	EPSD	TCGA;ICGC;COSMIC	2.638	Loss
CMGC_MAPK_JNK_MAPK8_ST	O43524	FOXO3	P45983	MAPK8	S411	S412C	412	Missense	proximal	1	no	2.727	2.876	EPSD	TCGA;ICGC;COSMIC	2.638	Up-regulation
CMGC_MAPK_JNK_MAPK8_ST	O43524	FOXO3	P45983	MAPK8	S425	L423M	423	Missense	proximal	-2	no	9.449	9.446	EPSD	TCGA;ICGC	2.638	Down-regulation
CMGC_MAPK_JNK_MAPK8_ST	O43524	FOXO3	P45983	MAPK8	S425	S425F	425	Missense	central	0	yes	9.449	0.000	EPSD	TCGA;ICGC;COSMIC	2.638	Loss
CMGC_MAPK_JNK_MAPK8_ST	O43524	FOXO3	P45983	MAPK8	S446	Q449H	449	Missense	distal	3	no	7.804	7.911	EPSD	TCGA;ICGC;COSMIC	2.638	Up-regulation
CMGC_MAPK_JNK_MAPK8_ST	O43524	FOXO3	P45983	MAPK8	T450	Q449H	449	Missense	proximal	-1	no	3.347	3.332	EPSD	TCGA;ICGC;COSMIC	2.638	Down-regulation
CMGC_MAPK_JNK_MAPK8_ST	O43524	FOXO3	P45983	MAPK8	S574	M580I	580	Missense	distal	6	no	8.089	8.119	PhosphoSitePlus	TCGA;ICGC;COSMIC	2.638	Up-regulation
CMGC_MAPK_JNK_MAPK8_ST	O43524	FOXO3	P45983	MAPK8	S588	D585A	585	Missense	distal	-3	no	3.500	3.723	EPSD	TCGA;ICGC;COSMIC	2.638	Up-regulation
CMGC_MAPK_JNK_MAPK8_ST	P10276	RARA	P45983	MAPK8	S74	P78S	78	Missense	distal	4	no	7.189	7.214	EPSD	TCGA;COSMIC	2.638	Up-regulation
CMGC_MAPK_JNK_MAPK8_ST	P10276	RARA	P45983	MAPK8	S77	P78S	78	Missense	proximal	1	no	7.003	-0.726	EPSD	TCGA;COSMIC	2.638	Loss
CMGC_MAPK_JNK_MAPK8_ST	P10276	RARA	P45983	MAPK8	T181	C174S	174	Missense	distal	-7	no	7.395	7.384	EPSD;PhosphoSitePlus	TCGA;COSMIC	2.638	Down-regulation
CMGC_MAPK_JNK_MAPK8_ST	O43521	BCL2L11	P45983	MAPK8	S59	P63S	63	Missense	distal	4	no	8.407	8.432	EPSD	TCGA;ICGC;COSMIC	2.638	Up-regulation
CMGC_MAPK_JNK_MAPK8_ST	O43521	BCL2L11	P45983	MAPK8	S69	P63S	63	Missense	distal	-6	no	7.830	7.741	EPSD	TCGA;ICGC;COSMIC	2.638	Down-regulation
CMGC_MAPK_JNK_MAPK8_ST	O43521	BCL2L11	P45983	MAPK8	S69	A68V	68	Missense	proximal	-1	no	7.830	7.794	EPSD	TCGA;ICGC;COSMIC	2.638	Down-regulation
CMGC_MAPK_JNK_MAPK8_ST	O43521	BCL2L11	P45983	MAPK8	S77	S77F	77	Missense	central	0	yes	6.762	0.000	EPSD	TCGA;ICGC;COSMIC	2.638	Loss
CMGC_MAPK_JNK_MAPK8_ST	O43521	BCL2L11	P45983	MAPK8	S77	R84T	84	Missense	distal	7	no	6.762	6.706	EPSD	TCGA;ICGC;COSMIC	2.638	Down-regulation
CMGC_MAPK_JNK_MAPK8_ST	P38936	CDKN1A	P45983	MAPK8	T57	G61V	61	Missense	distal	4	no	6.619	6.444	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	2.638	Down-regulation
CMGC_MAPK_JNK_MAPK8_ST	P38936	CDKN1A	P45983	MAPK8	T57	E56K	56	Missense	proximal	-1	no	6.619	6.622	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	2.638	Up-regulation
CMGC_MAPK_JNK_MAPK8_ST	P38936	CDKN1A	P45983	MAPK8	T57	P58L	58	Missense	proximal	1	no	6.619	-0.953	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	2.638	Loss
CMGC_MAPK_JNK_MAPK8_ST	P38936	CDKN1A	P45983	MAPK8	S98	R94W	94	Missense	distal	-4	no	8.346	8.102	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	2.638	Down-regulation
CMGC_MAPK_JNK_MAPK8_ST	P38936	CDKN1A	P45983	MAPK8	S98	R93S	93	Missense	distal	-5	no	8.346	7.942	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	2.638	Down-regulation
CMGC_MAPK_JNK_MAPK8_ST	P38936	CDKN1A	P45983	MAPK8	S98	R94P	94	Missense	distal	-4	no	8.346	8.482	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	2.638	Up-regulation
CMGC_MAPK_JNK_MAPK8_ST	P38936	CDKN1A	P45983	MAPK8	S98	P95S	95	Missense	distal	-3	no	8.346	8.508	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	2.638	Up-regulation
CMGC_MAPK_JNK_MAPK8_ST	P38936	CDKN1A	P45983	MAPK8	S130	D136H	136	Missense	distal	6	no	9.199	9.186	PhosphoSitePlus;EPSD	TCGA;ICGC;COSMIC	2.638	Down-regulation
CMGC_MAPK_JNK_MAPK8_ST	P38936	CDKN1A	P45983	MAPK8	S130	G132C	132	Missense	proximal	2	no	9.199	9.209	PhosphoSitePlus;EPSD	TCGA;ICGC;COSMIC	2.638	Up-regulation
CMGC_MAPK_JNK_MAPK8_ST	P38936	CDKN1A	P45983	MAPK8	S130	E128K	128	Missense	proximal	-2	no	9.199	9.197	PhosphoSitePlus;EPSD	TCGA;ICGC;COSMIC	2.638	Down-regulation
CMGC_MAPK_JNK_MAPK8_ST	P38936	CDKN1A	P45983	MAPK8	S130	G135A	135	Missense	distal	5	no	9.199	9.140	PhosphoSitePlus;EPSD	TCGA	2.638	Down-regulation
CMGC_MAPK_JNK_MAPK8_ST	P54259	ATN1	P45983	MAPK8	T64	P65L	65	Missense	proximal	1	no	7.457	-0.116	EPSD	TCGA;ICGC;COSMIC	2.638	Loss
CMGC_MAPK_JNK_MAPK8_ST	P54259	ATN1	P45983	MAPK8	T64	A62T	62	Missense	proximal	-2	no	7.457	7.427	EPSD	TCGA;ICGC	2.638	Down-regulation
CMGC_MAPK_JNK_MAPK8_ST	P54259	ATN1	P45983	MAPK8	S101	S103C	103	Missense	proximal	2	no	7.580	7.387	EPSD	TCGA;ICGC;COSMIC	2.638	Down-regulation
CMGC_MAPK_JNK_MAPK8_ST	P54259	ATN1	P45983	MAPK8	S101	R98W	98	Missense	distal	-3	no	7.580	7.495	EPSD	TCGA;ICGC;COSMIC	2.638	Down-regulation
CMGC_MAPK_JNK_MAPK8_ST	P54259	ATN1	P45983	MAPK8	S101	S107G	107	Missense	distal	6	no	7.580	7.523	EPSD	TCGA;ICGC;COSMIC	2.638	Down-regulation
CMGC_MAPK_JNK_MAPK8_ST	P54259	ATN1	P45983	MAPK8	S137	E142D	142	Missense	distal	5	no	7.571	7.629	EPSD	TCGA;ICGC	2.638	Up-regulation
CMGC_MAPK_JNK_MAPK8_ST	P54259	ATN1	P45983	MAPK8	S168	P162A	162	Missense	distal	-6	no	7.914	7.828	EPSD	TCGA;ICGC;COSMIC	2.638	Down-regulation
CMGC_MAPK_JNK_MAPK8_ST	P54259	ATN1	P45983	MAPK8	T190	H186Y	186	Missense	distal	-4	no	7.003	6.512	EPSD	TCGA;ICGC;COSMIC	2.638	Down-regulation
CMGC_MAPK_JNK_MAPK8_ST	P54259	ATN1	P45983	MAPK8	S355	L352V	352	Missense	distal	-3	no	8.141	8.088	EPSD	TCGA;ICGC;COSMIC	2.638	Down-regulation
CMGC_MAPK_JNK_MAPK8_ST	P54259	ATN1	P45983	MAPK8	T630	S632F	632	Missense	proximal	2	no	2.902	2.630	EPSD	TCGA;ICGC;COSMIC	2.638	Loss
CMGC_MAPK_JNK_MAPK8_ST	P54259	ATN1	P45983	MAPK8	T630	T630M	630	Missense	central	0	yes	2.902	0.000	EPSD	TCGA;ICGC;COSMIC	2.638	Loss
CMGC_MAPK_JNK_MAPK8_ST	P54259	ATN1	P45983	MAPK8	S632	S632F	632	Missense	central	0	yes	8.266	0.000	EPSD	TCGA;ICGC;COSMIC	2.638	Loss
CMGC_MAPK_JNK_MAPK8_ST	P54259	ATN1	P45983	MAPK8	S632	T630M	630	Missense	proximal	-2	no	8.266	8.150	EPSD	TCGA;ICGC;COSMIC	2.638	Down-regulation
CMGC_MAPK_JNK_MAPK8_ST	P54259	ATN1	P45983	MAPK8	S645	Y649C	649	Missense	distal	4	no	8.385	8.580	EPSD	TCGA;ICGC;COSMIC	2.638	Up-regulation
CMGC_MAPK_JNK_MAPK8_ST	P54259	ATN1	P45983	MAPK8	S645	A652V	652	Missense	distal	7	no	8.385	8.465	EPSD	TCGA;ICGC;COSMIC	2.638	Up-regulation
CMGC_MAPK_JNK_MAPK8_ST	P54259	ATN1	P45983	MAPK8	S645	P644L	644	Missense	proximal	-1	no	8.385	8.367	EPSD	TCGA;ICGC;COSMIC	2.638	Down-regulation
CMGC_MAPK_JNK_MAPK8_ST	P54259	ATN1	P45983	MAPK8	S645	G640R	640	Missense	distal	-5	no	8.385	8.413	EPSD	TCGA;ICGC;COSMIC	2.638	Up-regulation
CMGC_MAPK_JNK_MAPK8_ST	P54259	ATN1	P45983	MAPK8	T653	G656A	656	Missense	distal	3	no	6.419	6.247	EPSD	TCGA;ICGC;COSMIC	2.638	Down-regulation
CMGC_MAPK_JNK_MAPK8_ST	P54259	ATN1	P45983	MAPK8	T653	Y649C	649	Missense	distal	-4	no	6.419	6.885	EPSD	TCGA;ICGC;COSMIC	2.638	Up-regulation
CMGC_MAPK_JNK_MAPK8_ST	P54259	ATN1	P45983	MAPK8	T653	G660R	660	Missense	distal	7	no	6.419	6.417	EPSD	TCGA;ICGC;COSMIC	2.638	Down-regulation
CMGC_MAPK_JNK_MAPK8_ST	P54259	ATN1	P45983	MAPK8	T653	A652V	652	Missense	proximal	-1	no	6.419	6.383	EPSD	TCGA;ICGC;COSMIC	2.638	Down-regulation
CMGC_MAPK_JNK_MAPK8_ST	P54259	ATN1	P45983	MAPK8	S661	G656A	656	Missense	distal	-5	no	6.344	5.951	EPSD	TCGA;ICGC;COSMIC	2.638	Down-regulation
CMGC_MAPK_JNK_MAPK8_ST	P54259	ATN1	P45983	MAPK8	S661	G660R	660	Missense	proximal	-1	no	6.344	6.343	EPSD	TCGA;ICGC;COSMIC	2.638	Down-regulation
CMGC_MAPK_JNK_MAPK8_ST	P54259	ATN1	P45983	MAPK8	S661	S661A	661	Missense	central	0	yes	6.344	0.000	EPSD	TCGA;ICGC;COSMIC	2.638	Loss
CMGC_MAPK_JNK_MAPK8_ST	P54259	ATN1	P45983	MAPK8	T669	R674G	674	Missense	distal	5	no	7.862	7.858	EPSD	TCGA;ICGC;COSMIC	2.638	Down-regulation
CMGC_MAPK_JNK_MAPK8_ST	P54259	ATN1	P45983	MAPK8	S677	G681D	681	Missense	distal	4	no	7.184	7.326	EPSD	TCGA;ICGC	2.638	Up-regulation
CMGC_MAPK_JNK_MAPK8_ST	P54259	ATN1	P45983	MAPK8	S677	R674G	674	Missense	distal	-3	no	7.184	7.208	EPSD	TCGA;ICGC;COSMIC	2.638	Up-regulation
CMGC_MAPK_JNK_MAPK8_ST	P54259	ATN1	P45983	MAPK8	S780	F784L	784	Missense	distal	4	no	3.794	3.820	EPSD	TCGA;ICGC;COSMIC	2.638	Up-regulation
CMGC_MAPK_JNK_MAPK8_ST	P54259	ATN1	P45983	MAPK8	S896	H893Y	893	Missense	distal	-3	no	7.337	7.121	EPSD	TCGA;ICGC;COSMIC	2.638	Down-regulation
CMGC_MAPK_JNK_MAPK8_ST	P22736	NR4A1	P45983	MAPK8	T27	P28L	28	Missense	proximal	1	no	7.733	0.161	EPSD	TCGA;COSMIC	2.638	Loss
CMGC_MAPK_JNK_MAPK8_ST	P22736	NR4A1	P45983	MAPK8	S237	G232V	232	Missense	distal	-5	no	7.804	7.952	EPSD	TCGA;ICGC;COSMIC	2.638	Up-regulation
CMGC_MAPK_JNK_MAPK8_ST	Q6SZW1	SARM1	P45983	MAPK8	S548	G554C	554	Missense	distal	6	no	7.896	7.905	PhosphoSitePlus	TCGA;ICGC	2.638	Up-regulation
CMGC_MAPK_JNK_MAPK8_ST	Q6SZW1	SARM1	P45983	MAPK8	T561	G554C	554	Missense	distal	-7	no	7.505	7.503	EPSD	TCGA;ICGC	2.638	Down-regulation
CMGC_MAPK_JNK_MAPK8_ST	P19793	RXRA	P45983	MAPK8	S21	S27C	27	Missense	distal	6	no	9.786	9.738	EPSD	TCGA;ICGC;COSMIC	2.638	Down-regulation
CMGC_MAPK_JNK_MAPK8_ST	P19793	RXRA	P45983	MAPK8	S21	Q14K	14	Missense	distal	-7	no	9.786	9.779	EPSD	TCGA;ICGC;COSMIC	2.638	Down-regulation
CMGC_MAPK_JNK_MAPK8_ST	P19793	RXRA	P45983	MAPK8	S21	Q14L	14	Missense	distal	-7	no	9.786	9.800	EPSD	TCGA;ICGC;COSMIC	2.638	Up-regulation
CMGC_MAPK_JNK_MAPK8_ST	P19793	RXRA	P45983	MAPK8	S49	L47V	47	Missense	proximal	-2	no	7.546	7.498	EPSD	TCGA;ICGC;COSMIC	2.638	Down-regulation
CMGC_MAPK_JNK_MAPK8_ST	P19793	RXRA	P45983	MAPK8	S49	S43F	43	Missense	distal	-6	no	7.546	7.727	EPSD	TCGA;ICGC;COSMIC	2.638	Up-regulation
CMGC_MAPK_JNK_MAPK8_ST	P19793	RXRA	P45983	MAPK8	T82	S78L	78	Missense	distal	-4	no	9.219	8.227	EPSD	TCGA;ICGC;COSMIC	2.638	Down-regulation
CMGC_MAPK_JNK_MAPK8_ST	P19793	RXRA	P45983	MAPK8	T82	M77V	77	Missense	distal	-5	no	9.219	9.303	EPSD	TCGA;ICGC	2.638	Up-regulation
CMGC_MAPK_JNK_MAPK8_ST	P19793	RXRA	P45983	MAPK8	S225	P231L	231	Missense	distal	6	no	4.684	4.637	EPSD	TCGA;ICGC;COSMIC	2.638	Down-regulation
CMGC_MAPK_JNK_MAPK8_ST	P19793	RXRA	P45983	MAPK8	S225	A226T	226	Missense	proximal	1	no	4.684	4.044	EPSD	TCGA;ICGC;COSMIC;GDSC	2.638	Down-regulation
CMGC_MAPK_JNK_MAPK8_ST	P19793	RXRA	P45983	MAPK8	S260	V265I	265	Missense	distal	5	no	7.538	7.505	PhosphoSitePlus	TCGA	2.638	Down-regulation
CMGC_MAPK_JNK_MAPK8_ST	P19793	RXRA	P45983	MAPK8	S260	G255W	255	Missense	distal	-5	no	7.538	7.612	PhosphoSitePlus	TCGA;ICGC	2.638	Up-regulation
CMGC_MAPK_JNK_MAPK8_ST	O43379	WDR62	P45983	MAPK8	S33	P36S	36	Missense	distal	3	no	9.448	9.322	EPSD	TCGA;ICGC;COSMIC	2.638	Down-regulation
CMGC_MAPK_JNK_MAPK8_ST	O43379	WDR62	P45983	MAPK8	S33	R28L	28	Missense	distal	-5	no	9.448	9.516	EPSD	TCGA;ICGC;COSMIC	2.638	Up-regulation
CMGC_MAPK_JNK_MAPK8_ST	O43379	WDR62	P45983	MAPK8	S120	V127A	127	Missense	distal	7	no	7.127	7.048	EPSD	TCGA;ICGC;COSMIC	2.638	Down-regulation
CMGC_MAPK_JNK_MAPK8_ST	O43379	WDR62	P45983	MAPK8	S164	A159E	159	Missense	distal	-5	no	7.537	7.535	EPSD	TCGA;ICGC;COSMIC	2.638	Down-regulation
CMGC_MAPK_JNK_MAPK8_ST	O43379	WDR62	P45983	MAPK8	S211	S207L	207	Missense	distal	-4	no	3.339	2.347	EPSD	TCGA;ICGC;COSMIC	2.638	Loss
CMGC_MAPK_JNK_MAPK8_ST	O43379	WDR62	P45983	MAPK8	S445	K452I	452	Missense	distal	7	no	7.764	7.819	EPSD	TCGA;ICGC;COSMIC	2.638	Up-regulation
CMGC_MAPK_JNK_MAPK8_ST	O43379	WDR62	P45983	MAPK8	S445	R438L	438	Missense	distal	-7	no	7.764	7.768	EPSD	TCGA;ICGC;COSMIC	2.638	Up-regulation
CMGC_MAPK_JNK_MAPK8_ST	O43379	WDR62	P45983	MAPK8	S501	R496Q	496	Missense	distal	-5	no	9.046	8.731	EPSD	TCGA;ICGC;COSMIC;GDSC;CCLE	2.638	Down-regulation
CMGC_MAPK_JNK_MAPK8_ST	O43379	WDR62	P45983	MAPK8	S501	G494E	494	Missense	distal	-7	no	9.046	9.032	EPSD	TCGA;ICGC;COSMIC	2.638	Down-regulation
CMGC_MAPK_JNK_MAPK8_ST	O43379	WDR62	P45983	MAPK8	T785	T781M	781	Missense	distal	-4	no	8.735	8.032	EPSD	TCGA;ICGC;COSMIC;GDSC;CCLE	2.638	Down-regulation
CMGC_MAPK_JNK_MAPK8_ST	O43379	WDR62	P45983	MAPK8	S791	G795R	795	Missense	distal	4	no	2.745	2.724	EPSD	TCGA;ICGC;COSMIC	2.638	Down-regulation
CMGC_MAPK_JNK_MAPK8_ST	O43379	WDR62	P45983	MAPK8	S791	E796K	796	Missense	distal	5	no	2.745	2.736	EPSD	TCGA;ICGC;COSMIC	2.638	Down-regulation
CMGC_MAPK_JNK_MAPK8_ST	O43379	WDR62	P45983	MAPK8	S793	G795R	795	Missense	proximal	2	no	7.263	7.223	EPSD	TCGA;ICGC;COSMIC	2.638	Down-regulation
CMGC_MAPK_JNK_MAPK8_ST	O43379	WDR62	P45983	MAPK8	S793	E796K	796	Missense	distal	3	no	7.263	7.210	EPSD	TCGA;ICGC;COSMIC	2.638	Down-regulation
CMGC_MAPK_JNK_MAPK8_ST	O43379	WDR62	P45983	MAPK8	S793	D800N	800	Missense	distal	7	no	7.263	7.292	EPSD	TCGA;ICGC;COSMIC	2.638	Up-regulation
CMGC_MAPK_JNK_MAPK8_ST	O43379	WDR62	P45983	MAPK8	S982	K984M	984	Missense	proximal	2	no	8.302	7.973	EPSD	TCGA;ICGC;COSMIC	2.638	Down-regulation
CMGC_MAPK_JNK_MAPK8_ST	O43379	WDR62	P45983	MAPK8	S982	P988S	988	Missense	distal	6	no	8.302	8.327	EPSD	TCGA;ICGC;COSMIC;GDSC;CCLE	2.638	Up-regulation
CMGC_MAPK_JNK_MAPK8_ST	O43379	WDR62	P45983	MAPK8	S982	S987N	987	Missense	distal	5	no	8.302	8.372	EPSD	TCGA;ICGC;COSMIC	2.638	Up-regulation
CMGC_MAPK_JNK_MAPK8_ST	O43379	WDR62	P45983	MAPK8	S982	P988L	988	Missense	distal	6	no	8.302	8.255	EPSD	TCGA;ICGC;COSMIC;GDSC;CCLE	2.638	Down-regulation
CMGC_MAPK_JNK_MAPK8_ST	O43379	WDR62	P45983	MAPK8	S987	K984M	984	Missense	distal	-3	no	6.571	6.167	EPSD	TCGA;ICGC;COSMIC	2.638	Down-regulation
CMGC_MAPK_JNK_MAPK8_ST	O43379	WDR62	P45983	MAPK8	S987	P988S	988	Missense	proximal	1	no	6.571	-1.158	EPSD	TCGA;ICGC;COSMIC;GDSC;CCLE	2.638	Loss
CMGC_MAPK_JNK_MAPK8_ST	O43379	WDR62	P45983	MAPK8	S987	S987N	987	Missense	central	0	yes	6.571	0.000	EPSD	TCGA;ICGC;COSMIC	2.638	Loss
CMGC_MAPK_JNK_MAPK8_ST	O43379	WDR62	P45983	MAPK8	S987	P988L	988	Missense	proximal	1	no	6.571	-1.001	EPSD	TCGA;ICGC;COSMIC;GDSC;CCLE	2.638	Loss
CMGC_MAPK_JNK_MAPK8_ST	O43379	WDR62	P45983	MAPK8	S1008	S1008F	1008	Missense	central	0	yes	11.467	0.000	EPSD	TCGA;ICGC	2.638	Loss
CMGC_MAPK_JNK_MAPK8_ST	O43379	WDR62	P45983	MAPK8	T1053	S1049F	1049	Missense	distal	-4	no	7.656	6.719	PhosphoSitePlus	TCGA;ICGC;COSMIC	2.638	Down-regulation
CMGC_MAPK_JNK_MAPK8_ST	O43379	WDR62	P45983	MAPK8	S1405	S1410P	1410	Missense	distal	5	no	7.398	7.481	EPSD	TCGA;ICGC;COSMIC	2.638	Up-regulation
CMGC_MAPK_JNK_MAPK8_ST	P08047	SP1	P45983	MAPK8	S59	L61V	61	Missense	proximal	2	no	10.071	10.039	EPSD	TCGA;ICGC;COSMIC	2.638	Down-regulation
CMGC_MAPK_JNK_MAPK8_ST	P08047	SP1	P45983	MAPK8	S59	S59F	59	Missense	central	0	yes	10.071	0.000	EPSD	TCGA;ICGC;COSMIC	2.638	Loss
CMGC_MAPK_JNK_MAPK8_ST	P08047	SP1	P45983	MAPK8	S73	S69N	69	Missense	distal	-4	no	8.822	7.948	EPSD	TCGA;ICGC;COSMIC	2.638	Down-regulation
CMGC_MAPK_JNK_MAPK8_ST	P08047	SP1	P45983	MAPK8	S73	C68R	68	Missense	distal	-5	no	8.822	8.921	EPSD	TCGA;ICGC;COSMIC	2.638	Up-regulation
CMGC_MAPK_JNK_MAPK8_ST	P08047	SP1	P45983	MAPK8	S73	P74S	74	Missense	proximal	1	no	8.822	1.094	EPSD	TCGA;ICGC;COSMIC	2.638	Loss
CMGC_MAPK_JNK_MAPK8_ST	P08047	SP1	P45983	MAPK8	S73	S78N	78	Missense	distal	5	no	8.822	8.891	EPSD	TCGA;ICGC;COSMIC	2.638	Up-regulation
CMGC_MAPK_JNK_MAPK8_ST	P08047	SP1	P45983	MAPK8	T278	V272I	272	Missense	distal	-6	no	8.327	8.216	PhosphoSitePlus;EPSD	TCGA;ICGC;COSMIC	2.638	Down-regulation
CMGC_MAPK_JNK_MAPK8_ST	P08047	SP1	P45983	MAPK8	T278	S271N	271	Missense	distal	-7	no	8.327	8.342	PhosphoSitePlus;EPSD	TCGA;ICGC;COSMIC	2.638	Up-regulation
CMGC_MAPK_JNK_MAPK8_ST	P08047	SP1	P45983	MAPK8	T453	S446C	446	Missense	distal	-7	no	8.012	8.024	EPSD	TCGA;ICGC;COSMIC	2.638	Up-regulation
CMGC_MAPK_JNK_MAPK8_ST	P08047	SP1	P45983	MAPK8	S588	D590E	590	Missense	proximal	2	no	7.518	7.718	EPSD	TCGA;ICGC;COSMIC	2.638	Up-regulation
CMGC_MAPK_JNK_MAPK8_ST	P08047	SP1	P45983	MAPK8	S588	S588N	588	Missense	central	0	yes	7.518	0.000	EPSD	TCGA;ICGC;COSMIC	2.638	Loss
CMGC_MAPK_JNK_MAPK8_ST	P08047	SP1	P45983	MAPK8	T737	I744F	744	Missense	distal	7	no	2.815	2.850	EPSD	TCGA;ICGC;COSMIC	2.638	Up-regulation
CMGC_MAPK_JNK_MAPK8_ST	P08047	SP1	P45983	MAPK8	T737	G731S	731	Missense	distal	-6	no	2.815	2.664	EPSD	TCGA;ICGC;COSMIC	2.638	Down-regulation
CMGC_MAPK_JNK_MAPK8_ST	P08047	SP1	P45983	MAPK8	T737	A742T	742	Missense	distal	5	no	2.815	2.813	EPSD	TCGA;ICGC	2.638	Down-regulation
CMGC_MAPK_JNK_MAPK8_ST	P08047	SP1	P45983	MAPK8	T737	G736S	736	Missense	proximal	-1	no	2.815	2.840	EPSD	TCGA;ICGC;COSMIC	2.638	Up-regulation
CMGC_MAPK_JNK_MAPK8_ST	P08047	SP1	P45983	MAPK8	T739	I744F	744	Missense	distal	5	no	9.677	9.705	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	2.638	Up-regulation
CMGC_MAPK_JNK_MAPK8_ST	P08047	SP1	P45983	MAPK8	T739	A742T	742	Missense	distal	3	no	9.677	9.687	EPSD;PhosphoSitePlus	TCGA;ICGC	2.638	Up-regulation
CMGC_MAPK_JNK_MAPK8_ST	P08047	SP1	P45983	MAPK8	T739	G736S	736	Missense	distal	-3	no	9.677	9.958	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	2.638	Up-regulation
CMGC_MAPK_JNK_MAPK8_ST	P49023	PXN	P45983	MAPK8	T29	E27G	27	Missense	proximal	-2	no	6.499	6.401	EPSD	TCGA	2.638	Down-regulation
CMGC_MAPK_JNK_MAPK8_ST	P49023	PXN	P45983	MAPK8	S126	E128K	128	Missense	proximal	2	no	2.622	2.640	EPSD	TCGA;COSMIC	2.638	Gain
CMGC_MAPK_JNK_MAPK8_ST	P49023	PXN	P45983	MAPK8	S130	M134I	134	Missense	distal	4	no	8.678	8.899	EPSD	TCGA;COSMIC	2.638	Up-regulation
CMGC_MAPK_JNK_MAPK8_ST	P49023	PXN	P45983	MAPK8	S130	E128K	128	Missense	proximal	-2	no	8.678	8.675	EPSD	TCGA;COSMIC	2.638	Down-regulation
CMGC_MAPK_JNK_MAPK8_ST	P49023	PXN	P45983	MAPK8	S130	Q124H	124	Missense	distal	-6	no	8.678	8.758	EPSD	TCGA;COSMIC	2.638	Up-regulation
CMGC_MAPK_JNK_MAPK8_ST	P49023	PXN	P45983	MAPK8	S188	S188N	188	Missense	central	0	yes	9.041	0.000	EPSD	TCGA	2.638	Loss
CMGC_MAPK_JNK_MAPK8_ST	P49023	PXN	P45983	MAPK8	S230	S227F	227	Missense	distal	-3	no	8.290	7.916	EPSD	TCGA;COSMIC	2.638	Down-regulation
CMGC_MAPK_JNK_MAPK8_ST	P49023	PXN	P45983	MAPK8	S230	V237A	237	Missense	distal	7	no	8.290	8.211	EPSD	TCGA	2.638	Down-regulation
CMGC_MAPK_JNK_MAPK8_ST	P49023	PXN	P45983	MAPK8	S244	V248I	248	Missense	distal	4	no	8.587	8.917	EPSD	TCGA;COSMIC;CCLE	2.638	Up-regulation
CMGC_MAPK_JNK_MAPK8_ST	P49023	PXN	P45983	MAPK8	S244	R247H	247	Missense	distal	3	no	8.587	8.569	EPSD	TCGA;COSMIC	2.638	Down-regulation
CMGC_MAPK_JNK_MAPK8_ST	P49023	PXN	P45983	MAPK8	S244	V237A	237	Missense	distal	-7	no	8.587	8.569	EPSD	TCGA	2.638	Down-regulation
CMGC_MAPK_JNK_MAPK8_ST	Q9UQF2	MAPK8IP1	P45983	MAPK8	S187	S181Y	181	Missense	distal	-6	no	3.795	4.027	EPSD	TCGA	2.638	Up-regulation
CMGC_MAPK_JNK_MAPK8_ST	Q9UQF2	MAPK8IP1	P45983	MAPK8	S235	R238H	238	Missense	distal	3	no	9.188	9.170	EPSD	TCGA;COSMIC	2.638	Down-regulation
CMGC_MAPK_JNK_MAPK8_ST	Q9UQF2	MAPK8IP1	P45983	MAPK8	T284	E279K	279	Missense	distal	-5	no	7.758	7.681	EPSD	TCGA;COSMIC	2.638	Down-regulation
CMGC_MAPK_JNK_MAPK8_ST	Q9UQF2	MAPK8IP1	P45983	MAPK8	S341	E343Q	343	Missense	proximal	2	no	8.796	8.666	EPSD	TCGA	2.638	Down-regulation
CMGC_MAPK_JNK_MAPK8_ST	Q9UQF2	MAPK8IP1	P45983	MAPK8	S341	E343D	343	Missense	proximal	2	no	8.796	8.597	EPSD	TCGA	2.638	Down-regulation
CMGC_MAPK_JNK_MAPK8_ST	Q9UQF2	MAPK8IP1	P45983	MAPK8	S369	L374P	374	Missense	distal	5	no	3.225	3.227	EPSD	TCGA;COSMIC	2.638	Up-regulation
CMGC_MAPK_JNK_MAPK8_ST	Q9UQF2	MAPK8IP1	P45983	MAPK8	S369	S375P	375	Missense	distal	6	no	3.225	3.201	EPSD	TCGA	2.638	Down-regulation
CMGC_MAPK_JNK_MAPK8_ST	Q9UQF2	MAPK8IP1	P45983	MAPK8	S421	A426V	426	Missense	distal	5	no	7.986	8.059	EPSD	TCGA;COSMIC	2.638	Up-regulation
CMGC_MAPK_JNK_MAPK8_ST	Q9UQF2	MAPK8IP1	P45983	MAPK8	S421	V419I	419	Missense	proximal	-2	no	7.986	8.124	EPSD	TCGA;COSMIC	2.638	Up-regulation
CMGC_MAPK_JNK_MAPK8_ST	Q9UQF2	MAPK8IP1	P45983	MAPK8	S421	S425L	425	Missense	distal	4	no	7.986	7.555	EPSD	TCGA;COSMIC	2.638	Down-regulation
CMGC_MAPK_JNK_MAPK8_ST	Q9UQF2	MAPK8IP1	P45983	MAPK8	T448	S444F	444	Missense	distal	-4	no	9.114	8.176	EPSD	TCGA;COSMIC	2.638	Down-regulation
CMGC_MAPK_JNK_MAPK8_ST	Q07817	BCL2L1	P45983	MAPK8	T47	A50V	50	Missense	distal	3	no	7.989	8.217	PhosphoSitePlus;EPSD	TCGA;ICGC;COSMIC	2.638	Up-regulation
CMGC_MAPK_JNK_MAPK8_ST	Q07817	BCL2L1	P45983	MAPK8	S62	A64V	64	Missense	proximal	2	no	6.612	6.295	EPSD;PhosphoSitePlus	TCGA	2.638	Down-regulation
CMGC_MAPK_JNK_MAPK8_ST	Q07817	BCL2L1	P45983	MAPK8	T115	T109A	109	Missense	distal	-6	no	7.756	7.734	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	2.638	Down-regulation
CMGC_MAPK_JNK_MAPK8_ST	Q07817	BCL2L1	P45983	MAPK8	T115	Q121P	121	Missense	distal	6	no	7.756	7.746	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	2.638	Down-regulation
CMGC_MAPK_JNK_MAPK8_ST	Q07817	BCL2L1	P45983	MAPK8	T115	Q121H	121	Missense	distal	6	no	7.756	7.722	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	2.638	Down-regulation
CMGC_MAPK_JNK_MAPK8_ST	O43561	LAT	P45983	MAPK8	S84	P82S	82	Missense	proximal	-2	no	6.397	6.291	EPSD	TCGA;COSMIC;CCLE	2.638	Down-regulation
CMGC_MAPK_JNK_MAPK8_ST	P42226	STAT6	P45983	MAPK8	S498	S496Y	496	Missense	proximal	-2	no	3.007	2.878	EPSD	TCGA;ICGC	2.638	Down-regulation
CMGC_MAPK_JNK_MAPK8_ST	P42226	STAT6	P45983	MAPK8	S498	Q501H	501	Missense	distal	3	no	3.007	3.114	EPSD	TCGA;COSMIC	2.638	Up-regulation
CMGC_MAPK_JNK_MAPK8_ST	P42226	STAT6	P45983	MAPK8	S498	F502L	502	Missense	distal	4	no	3.007	3.033	EPSD	TCGA;ICGC;COSMIC	2.638	Up-regulation
CMGC_MAPK_JNK_MAPK8_ST	P42226	STAT6	P45983	MAPK8	S707	Y703F	703	Missense	distal	-4	no	6.698	6.993	PhosphoSitePlus	TCGA	2.638	Up-regulation
CMGC_MAPK_JNK_MAPK8_ST	P42226	STAT6	P45983	MAPK8	S707	I700T	700	Missense	distal	-7	no	6.698	6.690	PhosphoSitePlus	TCGA;COSMIC	2.638	Down-regulation
CMGC_MAPK_JNK_MAPK8_ST	P42226	STAT6	P45983	MAPK8	S707	S707P	707	Missense	central	0	yes	6.698	0.000	PhosphoSitePlus	TCGA;ICGC;COSMIC	2.638	Loss
CMGC_MAPK_JNK_MAPK8_ST	P42226	STAT6	P45983	MAPK8	S837	H838P	838	Missense	proximal	1	no	-1.139	6.776	EPSD	TCGA;ICGC;COSMIC	2.638	Gain
CMGC_MAPK_JNK_MAPK8_ST	Q13363	CTBP1	P45983	MAPK8	S422	V427G	427	Missense	distal	5	no	8.934	8.921	PhosphoSitePlus	TCGA;COSMIC	2.638	Down-regulation
CMGC_MAPK_JNK_MAPK8_ST	Q13950	RUNX2	P45983	MAPK8	S28	P29T	29	Missense	proximal	1	no	6.942	-0.045	EPSD	TCGA;COSMIC	2.638	Loss
CMGC_MAPK_JNK_MAPK8_ST	Q13950	RUNX2	P45983	MAPK8	S28	P29S	29	Missense	proximal	1	no	6.942	-0.787	EPSD	TCGA;COSMIC	2.638	Loss
CMGC_MAPK_JNK_MAPK8_ST	Q13950	RUNX2	P45983	MAPK8	T200	R193Q	193	Missense	distal	-7	no	2.782	2.772	EPSD	TCGA;COSMIC	2.638	Down-regulation
CMGC_MAPK_JNK_MAPK8_ST	Q13950	RUNX2	P45983	MAPK8	T200	V203I	203	Missense	distal	3	no	2.782	2.660	EPSD	TCGA;COSMIC	2.638	Down-regulation
CMGC_MAPK_JNK_MAPK8_ST	Q13950	RUNX2	P45983	MAPK8	T200	K195N	195	Missense	distal	-5	no	2.782	3.308	EPSD	TCGA;COSMIC	2.638	Up-regulation
CMGC_MAPK_JNK_MAPK8_ST	Q13950	RUNX2	P45983	MAPK8	T200	T202A	202	Missense	proximal	2	no	2.782	2.803	EPSD	TCGA;COSMIC	2.638	Up-regulation
CMGC_MAPK_JNK_MAPK8_ST	Q13950	RUNX2	P45983	MAPK8	T200	P207S	207	Missense	distal	7	no	2.782	2.743	EPSD	TCGA;COSMIC	2.638	Down-regulation
CMGC_MAPK_JNK_MAPK8_ST	Q13950	RUNX2	P45983	MAPK8	S294	P296S	296	Missense	proximal	2	no	8.601	8.787	EPSD	TCGA;COSMIC	2.638	Up-regulation
CMGC_MAPK_JNK_MAPK8_ST	Q13950	RUNX2	P45983	MAPK8	S305	S312F	312	Missense	distal	7	no	2.720	2.795	EPSD	TCGA;COSMIC	2.638	Up-regulation
CMGC_MAPK_JNK_MAPK8_ST	Q13950	RUNX2	P45983	MAPK8	S305	Q309E	309	Missense	distal	4	no	2.720	2.800	EPSD	TCGA;COSMIC	2.638	Up-regulation
CMGC_MAPK_JNK_MAPK8_ST	Q13950	RUNX2	P45983	MAPK8	S305	T311M	311	Missense	distal	6	no	2.720	2.659	EPSD	TCGA;COSMIC	2.638	Down-regulation
CMGC_MAPK_JNK_MAPK8_ST	Q13950	RUNX2	P45983	MAPK8	S305	M310T	310	Missense	distal	5	no	2.720	2.654	EPSD	TCGA;COSMIC	2.638	Down-regulation
CMGC_MAPK_JNK_MAPK8_ST	Q13950	RUNX2	P45983	MAPK8	S312	S312F	312	Missense	central	0	yes	9.441	0.000	EPSD	TCGA;COSMIC	2.638	Loss
CMGC_MAPK_JNK_MAPK8_ST	Q13950	RUNX2	P45983	MAPK8	S312	Q309E	309	Missense	distal	-3	no	9.441	9.598	EPSD	TCGA;COSMIC	2.638	Up-regulation
CMGC_MAPK_JNK_MAPK8_ST	Q13950	RUNX2	P45983	MAPK8	S312	T318S	318	Missense	distal	6	no	9.441	9.444	EPSD	TCGA;COSMIC	2.638	Up-regulation
CMGC_MAPK_JNK_MAPK8_ST	Q13950	RUNX2	P45983	MAPK8	S312	T311M	311	Missense	proximal	-1	no	9.441	9.414	EPSD	TCGA;COSMIC	2.638	Down-regulation
CMGC_MAPK_JNK_MAPK8_ST	Q13950	RUNX2	P45983	MAPK8	S312	M310T	310	Missense	proximal	-2	no	9.441	9.557	EPSD	TCGA;COSMIC	2.638	Up-regulation
CMGC_MAPK_JNK_MAPK8_ST	Q13950	RUNX2	P45983	MAPK8	S314	M310T	310	Missense	distal	-4	no	2.309	3.012	EPSD	TCGA;COSMIC	2.638	Gain
CMGC_MAPK_JNK_MAPK8_ST	Q13950	RUNX2	P45983	MAPK8	T319	S312F	312	Missense	distal	-7	no	8.050	8.066	EPSD	TCGA;COSMIC	2.638	Up-regulation
CMGC_MAPK_JNK_MAPK8_ST	Q13950	RUNX2	P45983	MAPK8	T319	R325Q	325	Missense	distal	6	no	8.050	8.096	EPSD	TCGA;COSMIC	2.638	Up-regulation
CMGC_MAPK_JNK_MAPK8_ST	Q13950	RUNX2	P45983	MAPK8	T319	T318S	318	Missense	proximal	-1	no	8.050	8.049	EPSD	TCGA;COSMIC	2.638	Down-regulation
CMGC_MAPK_JNK_MAPK8_ST	Q13950	RUNX2	P45983	MAPK8	T319	P320L	320	Missense	proximal	1	no	8.050	0.477	EPSD	TCGA;COSMIC	2.638	Loss
CMGC_MAPK_JNK_MAPK8_ST	Q13950	RUNX2	P45983	MAPK8	S465	P460S	460	Missense	distal	-5	no	5.598	5.486	EPSD	TCGA;COSMIC	2.638	Down-regulation
CMGC_MAPK_JNK_MAPK8_ST	Q13950	RUNX2	P45983	MAPK8	S465	P466S	466	Missense	proximal	1	no	5.598	-2.131	EPSD	TCGA;COSMIC	2.638	Loss
CMGC_MAPK_JNK_MAPK8_ST	Q13950	RUNX2	P45983	MAPK8	S503	V506F	506	Missense	distal	3	no	7.796	7.770	EPSD	TCGA;COSMIC	2.638	Down-regulation
CMGC_MAPK_JNK_MAPK8_ST	Q13950	RUNX2	P45983	MAPK8	S503	S503Y	503	Missense	central	0	yes	7.796	0.000	EPSD	TCGA;COSMIC	2.638	Loss
CMGC_MAPK_JNK_MAPK8_ST	Q14934	NFATC4	P45983	MAPK8	S819	G824V	824	Missense	distal	5	no	6.902	6.915	EPSD	TCGA;COSMIC	2.638	Up-regulation
CMGC_MAPK_JNK_MAPK8_ST	P17535	JUND	P45983	MAPK8	T117	T115I	115	Missense	proximal	-2	no	6.524	6.501	EPSD	TCGA;ICGC;COSMIC	2.638	Down-regulation
CMGC_MAPK_JNK_MAPK8_ST	P17535	JUND	P45983	MAPK8	T117	S121L	121	Missense	distal	4	no	6.524	6.092	EPSD	TCGA;ICGC;COSMIC	2.638	Down-regulation
CMGC_MAPK_JNK_MAPK8_ST	P17535	JUND	P45983	MAPK8	S255	S259W	259	Missense	distal	4	no	6.957	6.564	EPSD	TCGA;ICGC;COSMIC	2.638	Down-regulation
CMGC_MAPK_JNK_MAPK8_ST	P17535	JUND	P45983	MAPK8	S259	S259W	259	Missense	central	0	yes	8.532	0.000	EPSD	TCGA;ICGC;COSMIC	2.638	Loss
CMGC_MAPK_JNK_MAPK8_ST	P17535	JUND	P45983	MAPK8	S259	D264Y	264	Missense	distal	5	no	8.532	8.593	EPSD	TCGA;ICGC;COSMIC	2.638	Up-regulation
CMGC_MAPK_JNK_MAPK8_ST	P10415	BCL2	P45983	MAPK8	T56	A61T	61	Missense	distal	5	no	9.128	9.126	EPSD	TCGA;ICGC;COSMIC;CCLE	2.638	Down-regulation
CMGC_MAPK_JNK_MAPK8_ST	Q9Y6Q9	NCOA3	P45983	MAPK8	S13	L8V	8	Missense	distal	-5	no	3.637	3.690	EPSD	TCGA;ICGC;COSMIC	2.638	Up-regulation
CMGC_MAPK_JNK_MAPK8_ST	Q9Y6Q9	NCOA3	P45983	MAPK8	S13	L11M	11	Missense	proximal	-2	no	3.637	3.634	EPSD	TCGA;ICGC;COSMIC	2.638	Down-regulation
CMGC_MAPK_JNK_MAPK8_ST	Q9Y6Q9	NCOA3	P45983	MAPK8	T203	R198H	198	Missense	distal	-5	no	7.504	7.409	EPSD	TCGA;ICGC;COSMIC	2.638	Down-regulation
CMGC_MAPK_JNK_MAPK8_ST	Q9Y6Q9	NCOA3	P45983	MAPK8	T203	R198C	198	Missense	distal	-5	no	7.504	7.405	EPSD	TCGA;ICGC;COSMIC	2.638	Down-regulation
CMGC_MAPK_JNK_MAPK8_ST	Q9Y6Q9	NCOA3	P45983	MAPK8	S214	A213G	213	Missense	proximal	-1	no	7.609	7.582	EPSD	TCGA;ICGC;COSMIC	2.638	Down-regulation
CMGC_MAPK_JNK_MAPK8_ST	Q9Y6Q9	NCOA3	P45983	MAPK8	S214	A213V	213	Missense	proximal	-1	no	7.609	7.573	EPSD	TCGA;ICGC;COSMIC	2.638	Down-regulation
CMGC_MAPK_JNK_MAPK8_ST	Q9Y6Q9	NCOA3	P45983	MAPK8	S423	S429R	429	Missense	distal	6	no	2.882	2.822	EPSD	TCGA;ICGC;COSMIC	2.638	Down-regulation
CMGC_MAPK_JNK_MAPK8_ST	Q9Y6Q9	NCOA3	P45983	MAPK8	S450	S453F	453	Missense	distal	3	no	8.052	8.272	EPSD	TCGA;ICGC;COSMIC	2.638	Up-regulation
CMGC_MAPK_JNK_MAPK8_ST	Q9Y6Q9	NCOA3	P45983	MAPK8	S450	M448T	448	Missense	proximal	-2	no	8.052	8.169	EPSD	TCGA;ICGC;COSMIC	2.638	Up-regulation
CMGC_MAPK_JNK_MAPK8_ST	Q9Y6Q9	NCOA3	P45983	MAPK8	S450	S450P	450	Missense	central	0	yes	8.052	0.000	EPSD	TCGA;COSMIC	2.638	Loss
CMGC_MAPK_JNK_MAPK8_ST	Q9Y6Q9	NCOA3	P45983	MAPK8	S465	N458T	458	Missense	distal	-7	no	7.105	7.092	EPSD	TCGA;COSMIC	2.638	Down-regulation
CMGC_MAPK_JNK_MAPK8_ST	Q9Y6Q9	NCOA3	P45983	MAPK8	S470	L473F	473	Missense	distal	3	no	8.539	8.531	EPSD	TCGA;COSMIC	2.638	Down-regulation
CMGC_MAPK_JNK_MAPK8_ST	Q9Y6Q9	NCOA3	P45983	MAPK8	S505	P499A	499	Missense	distal	-6	no	8.149	8.063	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	2.638	Down-regulation
CMGC_MAPK_JNK_MAPK8_ST	Q9Y6Q9	NCOA3	P45983	MAPK8	S505	G511D	511	Missense	distal	6	no	8.149	8.172	EPSD;PhosphoSitePlus	TCGA	2.638	Up-regulation
CMGC_MAPK_JNK_MAPK8_ST	Q9Y6Q9	NCOA3	P45983	MAPK8	S543	S542L	542	Missense	proximal	-1	no	9.869	9.840	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	2.638	Down-regulation
CMGC_MAPK_JNK_MAPK8_ST	Q9Y6Q9	NCOA3	P45983	MAPK8	S543	S536F	536	Missense	distal	-7	no	9.869	9.885	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	2.638	Up-regulation
CMGC_MAPK_JNK_MAPK8_ST	Q9Y6Q9	NCOA3	P45983	MAPK8	S543	S539F	539	Missense	distal	-4	no	9.869	8.931	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	2.638	Down-regulation
CMGC_MAPK_JNK_MAPK8_ST	Q9Y6Q9	NCOA3	P45983	MAPK8	S551	P552L	552	Missense	proximal	1	no	6.839	-0.733	EPSD	TCGA;ICGC;COSMIC	2.638	Loss
CMGC_MAPK_JNK_MAPK8_ST	Q9Y6Q9	NCOA3	P45983	MAPK8	S640	K647R	647	Missense	distal	7	no	8.093	8.171	EPSD	TCGA;ICGC;COSMIC	2.638	Up-regulation
CMGC_MAPK_JNK_MAPK8_ST	Q9Y6Q9	NCOA3	P45983	MAPK8	S640	S644L	644	Missense	distal	4	no	8.093	7.661	EPSD	TCGA;COSMIC	2.638	Down-regulation
CMGC_MAPK_JNK_MAPK8_ST	Q9Y6Q9	NCOA3	P45983	MAPK8	S655	S662C	662	Missense	distal	7	no	6.793	6.845	EPSD	TCGA;COSMIC	2.638	Up-regulation
CMGC_MAPK_JNK_MAPK8_ST	Q9Y6Q9	NCOA3	P45983	MAPK8	S694	G692E	692	Missense	proximal	-2	no	7.525	7.624	EPSD	TCGA;ICGC;COSMIC	2.638	Up-regulation
CMGC_MAPK_JNK_MAPK8_ST	Q9Y6Q9	NCOA3	P45983	MAPK8	S712	S715F	715	Missense	distal	3	no	2.624	2.844	EPSD	TCGA;COSMIC	2.638	Gain
CMGC_MAPK_JNK_MAPK8_ST	Q9Y6Q9	NCOA3	P45983	MAPK8	S728	Q724H	724	Missense	distal	-4	no	9.493	9.031	EPSD	TCGA;COSMIC	2.638	Down-regulation
CMGC_MAPK_JNK_MAPK8_ST	Q9Y6Q9	NCOA3	P45983	MAPK8	S728	V721A	721	Missense	distal	-7	no	9.493	9.475	EPSD	TCGA	2.638	Down-regulation
CMGC_MAPK_JNK_MAPK8_ST	Q9Y6Q9	NCOA3	P45983	MAPK8	S860	S867G	867	Missense	distal	7	no	9.080	9.145	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	2.638	Up-regulation
CMGC_MAPK_JNK_MAPK8_ST	Q9Y6Q9	NCOA3	P45983	MAPK8	S860	R854Q	854	Missense	distal	-6	no	9.080	8.979	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	2.638	Down-regulation
CMGC_MAPK_JNK_MAPK8_ST	Q9Y6Q9	NCOA3	P45983	MAPK8	S867	I873M	873	Missense	distal	6	no	9.296	9.266	PhosphoSitePlus;EPSD	TCGA;ICGC;COSMIC	2.638	Down-regulation
CMGC_MAPK_JNK_MAPK8_ST	Q9Y6Q9	NCOA3	P45983	MAPK8	S867	S867G	867	Missense	central	0	yes	9.296	0.000	PhosphoSitePlus;EPSD	TCGA;ICGC;COSMIC	2.638	Loss
CMGC_MAPK_JNK_MAPK8_ST	Q9Y6Q9	NCOA3	P45983	MAPK8	S867	P868S	868	Missense	proximal	1	no	9.296	1.567	PhosphoSitePlus;EPSD	TCGA;ICGC;COSMIC	2.638	Loss
CMGC_MAPK_JNK_MAPK8_ST	Q9Y6Q9	NCOA3	P45983	MAPK8	S867	P868L	868	Missense	proximal	1	no	9.296	1.723	PhosphoSitePlus;EPSD	TCGA;ICGC;COSMIC	2.638	Loss
CMGC_MAPK_JNK_MAPK8_ST	Q9Y6Q9	NCOA3	P45983	MAPK8	T914	P915S	915	Missense	proximal	1	no	8.452	0.723	EPSD	TCGA;ICGC;COSMIC	2.638	Loss
CMGC_MAPK_JNK_MAPK8_ST	Q9Y6Q9	NCOA3	P45983	MAPK8	T914	R907Q	907	Missense	distal	-7	no	8.452	8.442	EPSD	TCGA;ICGC;COSMIC	2.638	Down-regulation
CMGC_MAPK_JNK_MAPK8_ST	Q9Y6Q9	NCOA3	P45983	MAPK8	S1330	S1337L	1337	Missense	distal	7	no	8.361	8.439	EPSD	TCGA;COSMIC;GDSC;CCLE	2.638	Up-regulation
CMGC_MAPK_JNK_MAPK8_ST	Q15672	TWIST1	P45983	MAPK8	S42	A46T	46	Missense	distal	4	no	2.687	2.638	EPSD	TCGA;ICGC;COSMIC	2.638	Down-regulation
CMGC_MAPK_JNK_MAPK8_ST	Q15672	TWIST1	P45983	MAPK8	S95	G97S	97	Missense	proximal	2	no	3.031	3.233	EPSD	TCGA;ICGC;COSMIC	2.638	Up-regulation
CMGC_MAPK_JNK_MAPK8_ST	Q15672	TWIST1	P45983	MAPK8	S99	G97S	97	Missense	proximal	-2	no	8.122	8.187	EPSD	TCGA;ICGC;COSMIC	2.638	Up-regulation
CMGC_MAPK_JNK_MAPK8_ST	Q9NR28	DIABLO	P45983	MAPK8	S6	R10H	10	Missense	distal	4	no	3.765	3.802	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	2.638	Up-regulation
CMGC_MAPK_JNK_MAPK8_ST	Q9NR28	DIABLO	P45983	MAPK8	S9	R10H	10	Missense	proximal	1	no	2.968	2.189	PhosphoSitePlus;EPSD	TCGA;ICGC;COSMIC	2.638	Loss
CMGC_MAPK_JNK_MAPK8_ST	Q9UGP4	LIMD1	P45983	MAPK8	S187	G191D	191	Missense	distal	4	no	7.606	7.748	EPSD	TCGA;ICGC;COSMIC	2.638	Up-regulation
CMGC_MAPK_JNK_MAPK8_ST	Q9UGP4	LIMD1	P45983	MAPK8	S197	G201S	201	Missense	distal	4	no	8.126	8.469	EPSD	TCGA;ICGC	2.638	Up-regulation
CMGC_MAPK_JNK_MAPK8_ST	Q9UGP4	LIMD1	P45983	MAPK8	S197	G191D	191	Missense	distal	-6	no	8.126	8.068	EPSD	TCGA;ICGC;COSMIC	2.638	Down-regulation
CMGC_MAPK_JNK_MAPK8_ST	Q9UGP4	LIMD1	P45983	MAPK8	S211	G213V	213	Missense	proximal	2	no	8.655	8.563	EPSD	TCGA;ICGC;COSMIC	2.638	Down-regulation
CMGC_MAPK_JNK_MAPK8_ST	Q9UGP4	LIMD1	P45983	MAPK8	T260	S256N	256	Missense	distal	-4	no	2.882	2.008	EPSD	TCGA;ICGC;COSMIC	2.638	Loss
CMGC_MAPK_JNK_MAPK8_ST	Q9UGP4	LIMD1	P45983	MAPK8	S277	L280V	280	Missense	distal	3	no	8.600	8.618	PhosphoSitePlus;EPSD	TCGA	2.638	Up-regulation
CMGC_MAPK_JNK_MAPK8_ST	Q9UGP4	LIMD1	P45983	MAPK8	S277	N282S	282	Missense	distal	5	no	8.600	8.531	PhosphoSitePlus;EPSD	TCGA;ICGC;COSMIC	2.638	Down-regulation
CMGC_MAPK_JNK_MAPK8_ST	Q9UGP4	LIMD1	P45983	MAPK8	T294	S296F	296	Missense	proximal	2	no	7.586	7.314	EPSD	TCGA;ICGC;COSMIC	2.638	Down-regulation
CMGC_MAPK_JNK_MAPK8_ST	Q9UGP4	LIMD1	P45983	MAPK8	S353	S360L	360	Missense	distal	7	no	8.411	8.490	EPSD	TCGA;ICGC;COSMIC	2.638	Up-regulation
CMGC_MAPK_JNK_MAPK8_ST	Q9UGP4	LIMD1	P45983	MAPK8	S353	S347R	347	Missense	distal	-6	no	8.411	8.566	EPSD	TCGA;ICGC;COSMIC	2.638	Up-regulation
CMGC_MAPK_JNK_MAPK8_ST	Q9UGP4	LIMD1	P45983	MAPK8	S353	S346F	346	Missense	distal	-7	no	8.411	8.428	EPSD	TCGA;ICGC;COSMIC	2.638	Up-regulation
CMGC_MAPK_JNK_MAPK8_ST	Q9UGP4	LIMD1	P45983	MAPK8	S384	L388F	388	Missense	distal	4	no	6.588	6.561	EPSD	TCGA;ICGC;COSMIC	2.638	Down-regulation
CMGC_MAPK_JNK_MAPK8_ST	Q9UGP4	LIMD1	P45983	MAPK8	S384	S387N	387	Missense	distal	3	no	6.588	6.791	EPSD	TCGA;ICGC	2.638	Up-regulation
CMGC_MAPK_JNK_MAPK8_ST	Q9UGP4	LIMD1	P45983	MAPK8	S421	R428M	428	Missense	distal	7	no	6.910	6.914	EPSD;PhosphoSitePlus	TCGA;ICGC	2.638	Up-regulation
CMGC_MAPK_JNK_MAPK8_ST	Q9UGP4	LIMD1	P45983	MAPK8	S424	R428M	428	Missense	distal	4	no	8.533	8.488	EPSD;PhosphoSitePlus	TCGA;ICGC	2.638	Down-regulation
CMGC_MAPK_JNK_MAPK8_ST	P35222	CTNNB1	P45983	MAPK8	S33	G34R	34	Missense	proximal	1	no	2.673	2.474	EPSD;PhosphoSitePlus	TCGA;COSMIC	2.638	Loss
CMGC_MAPK_JNK_MAPK8_ST	P35222	CTNNB1	P45983	MAPK8	S33	G34V	34	Missense	proximal	1	no	2.673	0.866	EPSD;PhosphoSitePlus	TCGA;COSMIC;CCLE	2.638	Loss
CMGC_MAPK_JNK_MAPK8_ST	P35222	CTNNB1	P45983	MAPK8	S33	G34E	34	Missense	proximal	1	no	2.673	1.297	EPSD;PhosphoSitePlus	TCGA;COSMIC;GDSC;CCLE	2.638	Loss
CMGC_MAPK_JNK_MAPK8_ST	P35222	CTNNB1	P45983	MAPK8	S33	S37C	37	Missense	distal	4	no	2.673	2.342	EPSD;PhosphoSitePlus	TCGA;COSMIC;GDSC;CCLE	2.638	Loss
CMGC_MAPK_JNK_MAPK8_ST	P35222	CTNNB1	P45983	MAPK8	S33	S37F	37	Missense	distal	4	no	2.673	2.215	EPSD;PhosphoSitePlus	TCGA;COSMIC;GDSC;CCLE	2.638	Loss
CMGC_MAPK_JNK_MAPK8_ST	P35222	CTNNB1	P45983	MAPK8	S33	S33F	33	Missense	central	0	yes	2.673	0.000	EPSD;PhosphoSitePlus	TCGA;COSMIC;GDSC;CCLE	2.638	Loss
CMGC_MAPK_JNK_MAPK8_ST	P35222	CTNNB1	P45983	MAPK8	S33	D32H	32	Missense	proximal	-1	no	2.673	2.667	EPSD;PhosphoSitePlus	TCGA;COSMIC	2.638	Down-regulation
CMGC_MAPK_JNK_MAPK8_ST	P35222	CTNNB1	P45983	MAPK8	S33	D32G	32	Missense	proximal	-1	no	2.673	2.662	EPSD;PhosphoSitePlus	TCGA;COSMIC	2.638	Down-regulation
CMGC_MAPK_JNK_MAPK8_ST	P35222	CTNNB1	P45983	MAPK8	S33	S33A	33	Missense	central	0	yes	2.673	0.000	EPSD;PhosphoSitePlus	TCGA;COSMIC	2.638	Loss
CMGC_MAPK_JNK_MAPK8_ST	P35222	CTNNB1	P45983	MAPK8	S33	S33Y	33	Missense	central	0	yes	2.673	0.000	EPSD;PhosphoSitePlus	TCGA;COSMIC;GDSC;CCLE	2.638	Loss
CMGC_MAPK_JNK_MAPK8_ST	P35222	CTNNB1	P45983	MAPK8	S33	D32V	32	Missense	proximal	-1	no	2.673	2.653	EPSD;PhosphoSitePlus	TCGA;COSMIC;CCLE	2.638	Down-regulation
CMGC_MAPK_JNK_MAPK8_ST	P35222	CTNNB1	P45983	MAPK8	S33	S33P	33	Missense	central	0	yes	2.673	0.000	EPSD;PhosphoSitePlus	TCGA;COSMIC;CCLE	2.638	Loss
CMGC_MAPK_JNK_MAPK8_ST	P35222	CTNNB1	P45983	MAPK8	S33	H36P	36	Missense	distal	3	no	2.673	2.635	EPSD;PhosphoSitePlus	TCGA;COSMIC;CCLE	2.638	Loss
CMGC_MAPK_JNK_MAPK8_ST	P35222	CTNNB1	P45983	MAPK8	S33	D32Y	32	Missense	proximal	-1	no	2.673	2.649	EPSD;PhosphoSitePlus	TCGA;COSMIC;CCLE	2.638	Down-regulation
CMGC_MAPK_JNK_MAPK8_ST	P35222	CTNNB1	P45983	MAPK8	S33	I35S	35	Missense	proximal	2	no	2.673	2.796	EPSD;PhosphoSitePlus	TCGA;COSMIC	2.638	Up-regulation
CMGC_MAPK_JNK_MAPK8_ST	P35222	CTNNB1	P45983	MAPK8	S33	S37Y	37	Missense	distal	4	no	2.673	2.148	EPSD;PhosphoSitePlus	TCGA;COSMIC	2.638	Loss
CMGC_MAPK_JNK_MAPK8_ST	P35222	CTNNB1	P45983	MAPK8	S33	S33C	33	Missense	central	0	yes	2.673	0.000	EPSD;PhosphoSitePlus	TCGA;COSMIC;GDSC;CCLE	2.638	Loss
CMGC_MAPK_JNK_MAPK8_ST	P35222	CTNNB1	P45983	MAPK8	S33	D32N	32	Missense	proximal	-1	no	2.673	2.659	EPSD;PhosphoSitePlus	TCGA;COSMIC;CCLE	2.638	Down-regulation
CMGC_MAPK_JNK_MAPK8_ST	P35222	CTNNB1	P45983	MAPK8	S33	S37P	37	Missense	distal	4	no	2.673	2.648	EPSD;PhosphoSitePlus	TCGA;COSMIC;GDSC;CCLE	2.638	Down-regulation
CMGC_MAPK_JNK_MAPK8_ST	P35222	CTNNB1	P45983	MAPK8	S33	D32A	32	Missense	proximal	-1	no	2.673	2.688	EPSD;PhosphoSitePlus	TCGA;COSMIC	2.638	Up-regulation
CMGC_MAPK_JNK_MAPK8_ST	P35222	CTNNB1	P45983	MAPK8	S37	G34R	34	Missense	distal	-3	no	3.848	3.824	PhosphoSitePlus;EPSD	TCGA;COSMIC	2.638	Down-regulation
CMGC_MAPK_JNK_MAPK8_ST	P35222	CTNNB1	P45983	MAPK8	S37	G34V	34	Missense	distal	-3	no	3.848	3.735	PhosphoSitePlus;EPSD	TCGA;COSMIC;CCLE	2.638	Down-regulation
CMGC_MAPK_JNK_MAPK8_ST	P35222	CTNNB1	P45983	MAPK8	S37	T41A	41	Missense	distal	4	no	3.848	3.896	PhosphoSitePlus;EPSD	TCGA;COSMIC;GDSC;CCLE	2.638	Up-regulation
CMGC_MAPK_JNK_MAPK8_ST	P35222	CTNNB1	P45983	MAPK8	S37	G34E	34	Missense	distal	-3	no	3.848	4.181	PhosphoSitePlus;EPSD	TCGA;COSMIC;GDSC;CCLE	2.638	Up-regulation
CMGC_MAPK_JNK_MAPK8_ST	P35222	CTNNB1	P45983	MAPK8	S37	S37C	37	Missense	central	0	yes	3.848	0.000	PhosphoSitePlus;EPSD	TCGA;COSMIC;GDSC;CCLE	2.638	Loss
CMGC_MAPK_JNK_MAPK8_ST	P35222	CTNNB1	P45983	MAPK8	S37	S37F	37	Missense	central	0	yes	3.848	0.000	PhosphoSitePlus;EPSD	TCGA;COSMIC;GDSC;CCLE	2.638	Loss
CMGC_MAPK_JNK_MAPK8_ST	P35222	CTNNB1	P45983	MAPK8	S37	S33F	33	Missense	distal	-4	no	3.848	2.910	PhosphoSitePlus;EPSD	TCGA;COSMIC;GDSC;CCLE	2.638	Down-regulation
CMGC_MAPK_JNK_MAPK8_ST	P35222	CTNNB1	P45983	MAPK8	S37	D32H	32	Missense	distal	-5	no	3.848	3.932	PhosphoSitePlus;EPSD	TCGA;COSMIC	2.638	Up-regulation
CMGC_MAPK_JNK_MAPK8_ST	P35222	CTNNB1	P45983	MAPK8	S37	D32G	32	Missense	distal	-5	no	3.848	3.999	PhosphoSitePlus;EPSD	TCGA;COSMIC	2.638	Up-regulation
CMGC_MAPK_JNK_MAPK8_ST	P35222	CTNNB1	P45983	MAPK8	S37	T41I	41	Missense	distal	4	no	3.848	3.707	PhosphoSitePlus;EPSD	TCGA;COSMIC	2.638	Down-regulation
CMGC_MAPK_JNK_MAPK8_ST	P35222	CTNNB1	P45983	MAPK8	S37	S33A	33	Missense	distal	-4	no	3.848	3.670	PhosphoSitePlus;EPSD	TCGA;COSMIC	2.638	Down-regulation
CMGC_MAPK_JNK_MAPK8_ST	P35222	CTNNB1	P45983	MAPK8	S37	S33Y	33	Missense	distal	-4	no	3.848	2.614	PhosphoSitePlus;EPSD	TCGA;COSMIC;GDSC;CCLE	2.638	Loss
CMGC_MAPK_JNK_MAPK8_ST	P35222	CTNNB1	P45983	MAPK8	S37	D32V	32	Missense	distal	-5	no	3.848	4.148	PhosphoSitePlus;EPSD	TCGA;COSMIC;CCLE	2.638	Up-regulation
CMGC_MAPK_JNK_MAPK8_ST	P35222	CTNNB1	P45983	MAPK8	S37	S33P	33	Missense	distal	-4	no	3.848	3.183	PhosphoSitePlus;EPSD	TCGA;COSMIC;CCLE	2.638	Down-regulation
CMGC_MAPK_JNK_MAPK8_ST	P35222	CTNNB1	P45983	MAPK8	S37	H36P	36	Missense	proximal	-1	no	3.848	3.858	PhosphoSitePlus;EPSD	TCGA;COSMIC;CCLE	2.638	Up-regulation
CMGC_MAPK_JNK_MAPK8_ST	P35222	CTNNB1	P45983	MAPK8	S37	D32Y	32	Missense	distal	-5	no	3.848	4.223	PhosphoSitePlus;EPSD	TCGA;COSMIC;CCLE	2.638	Up-regulation
CMGC_MAPK_JNK_MAPK8_ST	P35222	CTNNB1	P45983	MAPK8	S37	I35S	35	Missense	proximal	-2	no	3.848	3.846	PhosphoSitePlus;EPSD	TCGA;COSMIC	2.638	Down-regulation
CMGC_MAPK_JNK_MAPK8_ST	P35222	CTNNB1	P45983	MAPK8	S37	S37Y	37	Missense	central	0	yes	3.848	0.000	PhosphoSitePlus;EPSD	TCGA;COSMIC	2.638	Loss
CMGC_MAPK_JNK_MAPK8_ST	P35222	CTNNB1	P45983	MAPK8	S37	S33C	33	Missense	distal	-4	no	3.848	3.080	PhosphoSitePlus;EPSD	TCGA;COSMIC;GDSC;CCLE	2.638	Down-regulation
CMGC_MAPK_JNK_MAPK8_ST	P35222	CTNNB1	P45983	MAPK8	S37	S37A	37	Missense	central	0	yes	3.848	0.000	PhosphoSitePlus;EPSD	TCGA;COSMIC;GDSC;CCLE	2.638	Loss
CMGC_MAPK_JNK_MAPK8_ST	P35222	CTNNB1	P45983	MAPK8	S37	D32N	32	Missense	distal	-5	no	3.848	4.055	PhosphoSitePlus;EPSD	TCGA;COSMIC;CCLE	2.638	Up-regulation
CMGC_MAPK_JNK_MAPK8_ST	P35222	CTNNB1	P45983	MAPK8	S37	S33T	33	Missense	distal	-4	no	3.848	3.633	PhosphoSitePlus;EPSD	TCGA;COSMIC	2.638	Down-regulation
CMGC_MAPK_JNK_MAPK8_ST	P35222	CTNNB1	P45983	MAPK8	S37	T41N	41	Missense	distal	4	no	3.848	3.449	PhosphoSitePlus;EPSD	TCGA;COSMIC	2.638	Down-regulation
CMGC_MAPK_JNK_MAPK8_ST	P35222	CTNNB1	P45983	MAPK8	S37	S37P	37	Missense	central	0	yes	3.848	0.000	PhosphoSitePlus;EPSD	TCGA;COSMIC;GDSC;CCLE	2.638	Loss
CMGC_MAPK_JNK_MAPK8_ST	P35222	CTNNB1	P45983	MAPK8	S37	D32A	32	Missense	distal	-5	no	3.848	3.607	PhosphoSitePlus;EPSD	TCGA;COSMIC	2.638	Down-regulation
CMGC_MAPK_JNK_MAPK8_ST	P35222	CTNNB1	P45983	MAPK8	T41	S45F	45	Missense	distal	4	no	2.715	2.257	EPSD;PhosphoSitePlus	TCGA;COSMIC;GDSC;CCLE	2.638	Loss
CMGC_MAPK_JNK_MAPK8_ST	P35222	CTNNB1	P45983	MAPK8	T41	S45P	45	Missense	distal	4	no	2.715	2.690	EPSD;PhosphoSitePlus	TCGA;COSMIC;CCLE	2.638	Down-regulation
CMGC_MAPK_JNK_MAPK8_ST	P35222	CTNNB1	P45983	MAPK8	T41	G34V	34	Missense	distal	-7	no	2.715	2.720	EPSD;PhosphoSitePlus	TCGA;COSMIC;CCLE	2.638	Up-regulation
CMGC_MAPK_JNK_MAPK8_ST	P35222	CTNNB1	P45983	MAPK8	T41	T41A	41	Missense	central	0	yes	2.715	0.000	EPSD;PhosphoSitePlus	TCGA;COSMIC;GDSC;CCLE	2.638	Loss
CMGC_MAPK_JNK_MAPK8_ST	P35222	CTNNB1	P45983	MAPK8	T41	G34E	34	Missense	distal	-7	no	2.715	2.701	EPSD;PhosphoSitePlus	TCGA;COSMIC;GDSC;CCLE	2.638	Down-regulation
CMGC_MAPK_JNK_MAPK8_ST	P35222	CTNNB1	P45983	MAPK8	T41	S37C	37	Missense	distal	-4	no	2.715	1.947	EPSD;PhosphoSitePlus	TCGA;COSMIC;GDSC;CCLE	2.638	Loss
CMGC_MAPK_JNK_MAPK8_ST	P35222	CTNNB1	P45983	MAPK8	T41	S37F	37	Missense	distal	-4	no	2.715	1.777	EPSD;PhosphoSitePlus	TCGA;COSMIC;GDSC;CCLE	2.638	Loss
CMGC_MAPK_JNK_MAPK8_ST	P35222	CTNNB1	P45983	MAPK8	T41	T41I	41	Missense	central	0	yes	2.715	0.000	EPSD;PhosphoSitePlus	TCGA;COSMIC	2.638	Loss
CMGC_MAPK_JNK_MAPK8_ST	P35222	CTNNB1	P45983	MAPK8	T41	S45Y	45	Missense	distal	4	no	2.715	2.189	EPSD;PhosphoSitePlus	TCGA;COSMIC	2.638	Loss
CMGC_MAPK_JNK_MAPK8_ST	P35222	CTNNB1	P45983	MAPK8	T41	H36P	36	Missense	distal	-5	no	2.715	2.518	EPSD;PhosphoSitePlus	TCGA;COSMIC;CCLE	2.638	Loss
CMGC_MAPK_JNK_MAPK8_ST	P35222	CTNNB1	P45983	MAPK8	T41	I35S	35	Missense	distal	-6	no	2.715	2.621	EPSD;PhosphoSitePlus	TCGA;COSMIC	2.638	Loss
CMGC_MAPK_JNK_MAPK8_ST	P35222	CTNNB1	P45983	MAPK8	T41	S37Y	37	Missense	distal	-4	no	2.715	1.481	EPSD;PhosphoSitePlus	TCGA;COSMIC	2.638	Loss
CMGC_MAPK_JNK_MAPK8_ST	P35222	CTNNB1	P45983	MAPK8	T41	S37A	37	Missense	distal	-4	no	2.715	2.537	EPSD;PhosphoSitePlus	TCGA;COSMIC;GDSC;CCLE	2.638	Loss
CMGC_MAPK_JNK_MAPK8_ST	P35222	CTNNB1	P45983	MAPK8	T41	T41N	41	Missense	central	0	yes	2.715	0.000	EPSD;PhosphoSitePlus	TCGA;COSMIC	2.638	Loss
CMGC_MAPK_JNK_MAPK8_ST	P35222	CTNNB1	P45983	MAPK8	T41	S45C	45	Missense	distal	4	no	2.715	2.383	EPSD;PhosphoSitePlus	TCGA;COSMIC;GDSC;CCLE	2.638	Loss
CMGC_MAPK_JNK_MAPK8_ST	P35222	CTNNB1	P45983	MAPK8	T41	S37P	37	Missense	distal	-4	no	2.715	2.050	EPSD;PhosphoSitePlus	TCGA;COSMIC;GDSC;CCLE	2.638	Loss
CMGC_MAPK_JNK_MAPK8_ST	P35222	CTNNB1	P45983	MAPK8	S47	S45F	45	Missense	proximal	-2	no	2.699	2.584	EPSD	TCGA;COSMIC;GDSC;CCLE	2.638	Loss
CMGC_MAPK_JNK_MAPK8_ST	P35222	CTNNB1	P45983	MAPK8	S47	S45P	45	Missense	proximal	-2	no	2.699	2.804	EPSD	TCGA;COSMIC;CCLE	2.638	Up-regulation
CMGC_MAPK_JNK_MAPK8_ST	P35222	CTNNB1	P45983	MAPK8	S47	T41A	41	Missense	distal	-6	no	2.699	2.677	EPSD	TCGA;COSMIC;GDSC;CCLE	2.638	Down-regulation
CMGC_MAPK_JNK_MAPK8_ST	P35222	CTNNB1	P45983	MAPK8	S47	T41I	41	Missense	distal	-6	no	2.699	2.767	EPSD	TCGA;COSMIC	2.638	Up-regulation
CMGC_MAPK_JNK_MAPK8_ST	P35222	CTNNB1	P45983	MAPK8	S47	S45Y	45	Missense	proximal	-2	no	2.699	2.570	EPSD	TCGA;COSMIC	2.638	Loss
CMGC_MAPK_JNK_MAPK8_ST	P35222	CTNNB1	P45983	MAPK8	S47	E54D	54	Missense	distal	7	no	2.699	2.739	EPSD	TCGA;COSMIC	2.638	Up-regulation
CMGC_MAPK_JNK_MAPK8_ST	P35222	CTNNB1	P45983	MAPK8	S47	T41N	41	Missense	distal	-6	no	2.699	2.849	EPSD	TCGA;COSMIC	2.638	Up-regulation
CMGC_MAPK_JNK_MAPK8_ST	P35222	CTNNB1	P45983	MAPK8	S47	S45C	45	Missense	proximal	-2	no	2.699	2.634	EPSD	TCGA;COSMIC;GDSC;CCLE	2.638	Loss
CMGC_MAPK_JNK_MAPK8_ST	P35222	CTNNB1	P45983	MAPK8	S191	A197S	197	Missense	distal	6	no	8.259	8.262	EPSD	TCGA;COSMIC	2.638	Up-regulation
CMGC_MAPK_JNK_MAPK8_ST	P35222	CTNNB1	P45983	MAPK8	S191	R185G	185	Missense	distal	-6	no	8.259	8.255	EPSD	TCGA;COSMIC	2.638	Down-regulation
CMGC_MAPK_JNK_MAPK8_ST	P35222	CTNNB1	P45983	MAPK8	S605	P606L	606	Missense	proximal	1	no	6.304	-1.269	EPSD	TCGA;COSMIC	2.638	Loss
CMGC_MAPK_JNK_MAPK8_ST	Q99607	ELF4	P45983	MAPK8	S188	D192G	192	Missense	distal	4	no	6.118	5.977	EPSD	TCGA;ICGC;COSMIC	2.638	Down-regulation
CMGC_MAPK_JNK_MAPK8_ST	Q99607	ELF4	P45983	MAPK8	S188	N184S	184	Missense	distal	-4	no	6.118	6.992	EPSD	TCGA;ICGC;COSMIC	2.638	Up-regulation
CMGC_MAPK_JNK_MAPK8_ST	Q99607	ELF4	P45983	MAPK8	S188	T181N	181	Missense	distal	-7	no	6.118	6.131	EPSD	TCGA;ICGC	2.638	Up-regulation
CMGC_MAPK_JNK_MAPK8_ST	Q99607	ELF4	P45983	MAPK8	S188	R185Q	185	Missense	distal	-3	no	6.118	6.317	EPSD	TCGA;ICGC	2.638	Up-regulation
CMGC_MAPK_JNK_MAPK8_ST	Q99607	ELF4	P45983	MAPK8	S194	D192G	192	Missense	proximal	-2	no	2.695	2.650	EPSD	TCGA;ICGC;COSMIC	2.638	Down-regulation
CMGC_MAPK_JNK_MAPK8_ST	Q99607	ELF4	P45983	MAPK8	S194	K200R	200	Missense	distal	6	no	2.695	2.617	EPSD	TCGA;ICGC	2.638	Loss
CMGC_MAPK_JNK_MAPK8_ST	Q99607	ELF4	P45983	MAPK8	T531	R526M	526	Missense	distal	-5	no	3.257	3.294	EPSD	TCGA;ICGC	2.638	Up-regulation
CMGC_MAPK_JNK_MAPK8_ST	Q99607	ELF4	P45983	MAPK8	S641	L637F	637	Missense	distal	-4	no	8.197	8.251	PhosphoSitePlus	TCGA;ICGC;COSMIC	2.638	Up-regulation
CMGC_MAPK_JNK_MAPK8_ST	Q99607	ELF4	P45983	MAPK8	T643	F650C	650	Missense	distal	7	no	6.925	6.902	EPSD	TCGA;ICGC	2.638	Down-regulation
CMGC_MAPK_JNK_MAPK8_ST	Q99607	ELF4	P45983	MAPK8	S648	P652H	652	Missense	distal	4	no	7.748	7.445	EPSD	TCGA;ICGC;COSMIC	2.638	Down-regulation
CMGC_MAPK_JNK_MAPK8_ST	Q99607	ELF4	P45983	MAPK8	S648	F650C	650	Missense	proximal	2	no	7.748	7.827	EPSD	TCGA;ICGC	2.638	Up-regulation
CMGC_MAPK_JNK_MAPK8_ST	Q99607	ELF4	P45983	MAPK8	S648	S654F	654	Missense	distal	6	no	7.748	7.679	EPSD	TCGA;ICGC	2.638	Down-regulation
CMGC_MAPK_JNK_MAPK8_ST	P05412	JUN	P45983	MAPK8	S73	S73L	73	Missense	central	0	yes	8.495	0.000	PhosphoSitePlus;EPSD	TCGA;ICGC;COSMIC	2.638	Loss
CMGC_MAPK_JNK_MAPK8_ST	P05412	JUN	P45983	MAPK8	T91	G86W	86	Missense	distal	-5	no	8.328	8.402	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	2.638	Up-regulation
CMGC_MAPK_JNK_MAPK8_ST	P05412	JUN	P45983	MAPK8	T93	G86W	86	Missense	distal	-7	no	8.490	8.493	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	2.638	Up-regulation
CMGC_MAPK_JNK_MAPK8_ST	P05412	JUN	P45983	MAPK8	T93	C99Y	99	Missense	distal	6	no	8.490	8.452	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	2.638	Down-regulation
CMGC_MAPK_JNK_MAPK8_ST	P05412	JUN	P45983	MAPK8	T239	P244L	244	Missense	distal	5	no	5.188	5.186	EPSD	TCGA;ICGC;COSMIC	2.638	Down-regulation
CMGC_MAPK_JNK_MAPK8_ST	P05412	JUN	P45983	MAPK8	S243	P244L	244	Missense	proximal	1	no	7.365	-0.207	EPSD	TCGA;ICGC;COSMIC	2.638	Loss
CMGC_MAPK_JNK_MAPK8_ST	Q14451	GRB7	P45983	MAPK8	T27	P31L	31	Missense	distal	4	no	7.100	6.693	EPSD	TCGA;ICGC;COSMIC	2.638	Down-regulation
CMGC_MAPK_JNK_MAPK8_ST	Q14451	GRB7	P45983	MAPK8	T33	P31L	31	Missense	proximal	-2	no	6.076	5.883	EPSD	TCGA;ICGC;COSMIC	2.638	Down-regulation
CMGC_MAPK_JNK_MAPK8_ST	P30305	CDC25B	P45983	MAPK8	S42	S36Y	36	Missense	distal	-6	no	8.088	8.320	EPSD	TCGA;ICGC	2.638	Up-regulation
CMGC_MAPK_JNK_MAPK8_ST	P30305	CDC25B	P45983	MAPK8	S42	L40P	40	Missense	proximal	-2	no	8.088	8.281	EPSD	TCGA;ICGC;COSMIC	2.638	Up-regulation
CMGC_MAPK_JNK_MAPK8_ST	P30305	CDC25B	P45983	MAPK8	S42	S49A	49	Missense	distal	7	no	8.088	8.094	EPSD	TCGA;ICGC;COSMIC	2.638	Up-regulation
CMGC_MAPK_JNK_MAPK8_ST	P30305	CDC25B	P45983	MAPK8	S42	H37N	37	Missense	distal	-5	no	8.088	8.211	EPSD	TCGA;ICGC	2.638	Up-regulation
CMGC_MAPK_JNK_MAPK8_ST	P30305	CDC25B	P45983	MAPK8	S50	S49A	49	Missense	proximal	-1	no	9.900	9.902	EPSD	TCGA;ICGC;COSMIC	2.638	Up-regulation
CMGC_MAPK_JNK_MAPK8_ST	P30305	CDC25B	P45983	MAPK8	S115	G110C	110	Missense	distal	-5	no	7.331	7.259	EPSD	TCGA;ICGC;COSMIC	2.638	Down-regulation
CMGC_MAPK_JNK_MAPK8_ST	P30305	CDC25B	P45983	MAPK8	S115	G110D	110	Missense	distal	-5	no	7.331	7.179	EPSD	TCGA;COSMIC	2.638	Down-regulation
CMGC_MAPK_JNK_MAPK8_ST	P30305	CDC25B	P45983	MAPK8	S115	S115F	115	Missense	central	0	yes	7.331	0.000	EPSD	TCGA;COSMIC	2.638	Loss
CMGC_MAPK_JNK_MAPK8_ST	P30305	CDC25B	P45983	MAPK8	S117	G110C	110	Missense	distal	-7	no	7.637	7.635	EPSD	TCGA;ICGC;COSMIC	2.638	Down-regulation
CMGC_MAPK_JNK_MAPK8_ST	P30305	CDC25B	P45983	MAPK8	S117	G110D	110	Missense	distal	-7	no	7.637	7.632	EPSD	TCGA;COSMIC	2.638	Down-regulation
CMGC_MAPK_JNK_MAPK8_ST	P30305	CDC25B	P45983	MAPK8	S117	S115F	115	Missense	proximal	-2	no	7.637	7.522	EPSD	TCGA;COSMIC	2.638	Down-regulation
CMGC_MAPK_JNK_MAPK8_ST	P30305	CDC25B	P45983	MAPK8	S160	S160I	160	Missense	central	0	yes	7.307	0.000	EPSD	TCGA	2.638	Loss
CMGC_MAPK_JNK_MAPK8_ST	P30305	CDC25B	P45983	MAPK8	S160	S160C	160	Missense	central	0	yes	7.307	0.000	EPSD	TCGA;COSMIC	2.638	Loss
CMGC_MAPK_JNK_MAPK8_ST	P30305	CDC25B	P45983	MAPK8	S160	P153L	153	Missense	distal	-7	no	7.307	7.319	EPSD	TCGA;ICGC;COSMIC	2.638	Up-regulation
CMGC_MAPK_JNK_MAPK8_ST	P30305	CDC25B	P45983	MAPK8	S160	V162M	162	Missense	proximal	2	no	7.307	7.352	EPSD	TCGA;ICGC;COSMIC	2.638	Up-regulation
CMGC_MAPK_JNK_MAPK8_ST	P30305	CDC25B	P45983	MAPK8	S160	R164Q	164	Missense	distal	4	no	7.307	7.541	EPSD	TCGA	2.638	Up-regulation
CMGC_MAPK_JNK_MAPK8_ST	P30305	CDC25B	P45983	MAPK8	S188	E193D	193	Missense	distal	5	no	3.282	3.339	EPSD	TCGA	2.638	Up-regulation
CMGC_MAPK_JNK_MAPK8_ST	P30305	CDC25B	P45983	MAPK8	S188	D191H	191	Missense	distal	3	no	3.282	3.325	EPSD	TCGA;COSMIC	2.638	Up-regulation
CMGC_MAPK_JNK_MAPK8_ST	P30305	CDC25B	P45983	MAPK8	S238	D240H	240	Missense	proximal	2	no	7.003	6.956	EPSD	TCGA;ICGC	2.638	Down-regulation
CMGC_MAPK_JNK_MAPK8_ST	P30305	CDC25B	P45983	MAPK8	S238	V245M	245	Missense	distal	7	no	7.003	6.986	EPSD	TCGA;COSMIC	2.638	Down-regulation
CMGC_MAPK_JNK_MAPK8_ST	P30305	CDC25B	P45983	MAPK8	S238	S238R	238	Missense	central	0	yes	7.003	0.000	EPSD	TCGA;ICGC;COSMIC;CCLE	2.638	Loss
CMGC_MAPK_JNK_MAPK8_ST	P30305	CDC25B	P45983	MAPK8	S238	L237I	237	Missense	proximal	-1	no	7.003	7.020	EPSD	TCGA	2.638	Up-regulation
CMGC_MAPK_JNK_MAPK8_ST	P30305	CDC25B	P45983	MAPK8	S238	R241Q	241	Missense	distal	3	no	7.003	6.878	EPSD	TCGA;ICGC	2.638	Down-regulation
CMGC_MAPK_JNK_MAPK8_ST	P30305	CDC25B	P45983	MAPK8	S249	V245M	245	Missense	distal	-4	no	8.352	8.468	EPSD	TCGA;COSMIC	2.638	Up-regulation
CMGC_MAPK_JNK_MAPK8_ST	P30305	CDC25B	P45983	MAPK8	S321	R317Q	317	Missense	distal	-4	no	9.454	9.974	EPSD	TCGA;COSMIC	2.638	Up-regulation
CMGC_MAPK_JNK_MAPK8_ST	P30305	CDC25B	P45983	MAPK8	T344	P339L	339	Missense	distal	-5	no	5.844	6.204	EPSD	TCGA;ICGC;COSMIC	2.638	Up-regulation
CMGC_MAPK_JNK_MAPK8_ST	P30305	CDC25B	P45983	MAPK8	T344	P345L	345	Missense	proximal	1	no	5.844	-1.729	EPSD	TCGA;COSMIC	2.638	Loss
CMGC_MAPK_JNK_MAPK8_ST	P30305	CDC25B	P45983	MAPK8	T344	R338Q	338	Missense	distal	-6	no	5.844	5.742	EPSD	TCGA;ICGC;COSMIC	2.638	Down-regulation
CMGC_MAPK_JNK_MAPK8_ST	P30305	CDC25B	P45983	MAPK8	T355	E358K	358	Missense	distal	3	no	6.880	6.826	EPSD	TCGA;ICGC;COSMIC	2.638	Down-regulation
CMGC_MAPK_JNK_MAPK8_ST	P30305	CDC25B	P45983	MAPK8	T355	R352W	352	Missense	distal	-3	no	6.880	6.794	EPSD	TCGA;ICGC;COSMIC	2.638	Down-regulation
CMGC_MAPK_JNK_MAPK8_ST	P30305	CDC25B	P45983	MAPK8	S470	E464D	464	Missense	distal	-6	no	8.647	8.748	EPSD	TCGA;ICGC	2.638	Up-regulation
CMGC_MAPK_JNK_MAPK8_ST	P30305	CDC25B	P45983	MAPK8	S470	A463V	463	Missense	distal	-7	no	8.647	8.666	EPSD	TCGA;ICGC;COSMIC	2.638	Up-regulation
CMGC_MAPK_JNK_MAPK8_ST	Q13043	STK4	P45983	MAPK8	S82	H84Y	84	Missense	proximal	2	no	7.389	7.195	PhosphoSitePlus	TCGA;ICGC;COSMIC	2.638	Down-regulation
CMGC_MAPK_JNK_MAPK8_ST	Q13043	STK4	P45983	MAPK8	S82	P83L	83	Missense	proximal	1	no	7.389	-0.184	PhosphoSitePlus	TCGA;ICGC;COSMIC	2.638	Loss
CMGC_MAPK_JNK_MAPK8_ST	Q13043	STK4	P45983	MAPK8	T187	R181Q	181	Missense	distal	-6	no	6.998	6.896	EPSD	TCGA;COSMIC	2.638	Down-regulation
CMGC_MAPK_JNK_MAPK8_ST	Q13043	STK4	P45983	MAPK8	S265	A270T	270	Missense	distal	5	no	8.206	8.204	EPSD	TCGA;COSMIC	2.638	Down-regulation
CMGC_MAPK_JNK_MAPK8_ST	Q13043	STK4	P45983	MAPK8	S265	P266L	266	Missense	proximal	1	no	8.206	0.634	EPSD	TCGA;COSMIC	2.638	Loss
CMGC_MAPK_JNK_MAPK8_ST	Q13043	STK4	P45983	MAPK8	S438	D443N	443	Missense	distal	5	no	3.869	3.892	EPSD	TCGA;COSMIC	2.638	Up-regulation
CMGC_MAPK_JNK_MAPK8_ST	Q13043	STK4	P45983	MAPK8	S438	D432Y	432	Missense	distal	-6	no	3.869	4.008	EPSD	TCGA;COSMIC	2.638	Up-regulation
CMGC_MAPK_JNK_MAPK8_ST	Q13043	STK4	P45983	MAPK8	S438	D443G	443	Missense	distal	5	no	3.869	3.891	EPSD	TCGA;COSMIC	2.638	Up-regulation
CMGC_MAPK_JNK_MAPK8_ST	Q13043	STK4	P45983	MAPK8	S438	K437N	437	Missense	proximal	-1	no	3.869	3.834	EPSD	TCGA;COSMIC	2.638	Down-regulation
CMGC_MAPK_JNK_MAPK8_ST	Q13043	STK4	P45983	MAPK8	S438	E434K	434	Missense	distal	-4	no	3.869	4.125	EPSD	TCGA	2.638	Up-regulation
CMGC_MAPK_JNK_MAPK8_ST	Q07820	MCL1	P45983	MAPK8	S121	E123K	123	Missense	proximal	2	no	6.612	6.629	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	2.638	Up-regulation
CMGC_MAPK_JNK_MAPK8_ST	Q07820	MCL1	P45983	MAPK8	T163	S162W	162	Missense	proximal	-1	no	8.911	8.882	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	2.638	Down-regulation
CMGC_MAPK_JNK_MAPK8_ST	P30307	CDC25C	P45983	MAPK8	T67	D73N	73	Missense	distal	6	no	7.370	7.339	EPSD	TCGA;ICGC;COSMIC	2.638	Down-regulation
CMGC_MAPK_JNK_MAPK8_ST	P30307	CDC25C	P45983	MAPK8	S122	L127I	127	Missense	distal	5	no	7.676	7.642	EPSD	TCGA;ICGC	2.638	Down-regulation
CMGC_MAPK_JNK_MAPK8_ST	P30307	CDC25C	P45983	MAPK8	S122	L127V	127	Missense	distal	5	no	7.676	7.675	EPSD	TCGA;ICGC;COSMIC	2.638	Down-regulation
CMGC_MAPK_JNK_MAPK8_ST	P30307	CDC25C	P45983	MAPK8	T130	G137C	137	Missense	distal	7	no	6.005	5.993	EPSD	TCGA;ICGC	2.638	Down-regulation
CMGC_MAPK_JNK_MAPK8_ST	P30307	CDC25C	P45983	MAPK8	T130	L127I	127	Missense	distal	-3	no	6.005	6.187	EPSD	TCGA;ICGC	2.638	Up-regulation
CMGC_MAPK_JNK_MAPK8_ST	P30307	CDC25C	P45983	MAPK8	T130	L127V	127	Missense	distal	-3	no	6.005	5.953	EPSD	TCGA;ICGC;COSMIC	2.638	Down-regulation
CMGC_MAPK_JNK_MAPK8_ST	P30307	CDC25C	P45983	MAPK8	S214	P215Q	215	Missense	proximal	1	no	8.343	1.234	EPSD	TCGA;ICGC;COSMIC	2.638	Loss
CMGC_MAPK_JNK_MAPK8_ST	P30307	CDC25C	P45983	MAPK8	S214	R213H	213	Missense	proximal	-1	no	8.343	8.348	EPSD	TCGA;ICGC;COSMIC	2.638	Up-regulation
CMGC_MAPK_JNK_MAPK8_ST	P30307	CDC25C	P45983	MAPK8	S214	R213C	213	Missense	proximal	-1	no	8.343	8.349	EPSD	TCGA;ICGC;COSMIC	2.638	Up-regulation
CMGC_MAPK_JNK_MAPK8_ST	P30307	CDC25C	P45983	MAPK8	S214	S214F	214	Missense	central	0	yes	8.343	0.000	EPSD	TCGA;ICGC;COSMIC	2.638	Loss
CMGC_MAPK_JNK_MAPK8_ST	P30307	CDC25C	P45983	MAPK8	S214	L221S	221	Missense	distal	7	no	8.343	8.265	EPSD	TCGA;ICGC;COSMIC	2.638	Down-regulation
CMGC_MAPK_JNK_MAPK8_ST	P30307	CDC25C	P45983	MAPK8	S214	P218S	218	Missense	distal	4	no	8.343	8.368	EPSD	TCGA;ICGC	2.638	Up-regulation
CMGC_MAPK_JNK_MAPK8_ST	Q8WYQ5	DGCR8	P45983	MAPK8	S6	P9L	9	Missense	distal	3	no	8.332	8.434	EPSD	TCGA;ICGC;COSMIC	2.638	Up-regulation
CMGC_MAPK_JNK_MAPK8_ST	Q8WYQ5	DGCR8	P45983	MAPK8	S6	P11S	11	Missense	distal	5	no	8.332	8.249	EPSD	TCGA;ICGC;COSMIC	2.638	Down-regulation
CMGC_MAPK_JNK_MAPK8_ST	Q8WYQ5	DGCR8	P45983	MAPK8	S8	P9L	9	Missense	proximal	1	no	7.596	0.024	EPSD	TCGA;ICGC;COSMIC	2.638	Loss
CMGC_MAPK_JNK_MAPK8_ST	Q8WYQ5	DGCR8	P45983	MAPK8	S8	P11S	11	Missense	distal	3	no	7.596	7.471	EPSD	TCGA;ICGC;COSMIC	2.638	Down-regulation
CMGC_MAPK_JNK_MAPK8_ST	Q8WYQ5	DGCR8	P45983	MAPK8	S35	A29S	29	Missense	distal	-6	no	7.738	7.734	EPSD	TCGA;ICGC;COSMIC	2.638	Down-regulation
CMGC_MAPK_JNK_MAPK8_ST	Q8WYQ5	DGCR8	P45983	MAPK8	S35	P36S	36	Missense	proximal	1	no	7.738	0.009	EPSD	TCGA;ICGC;COSMIC	2.638	Loss
CMGC_MAPK_JNK_MAPK8_ST	Q8WYQ5	DGCR8	P45983	MAPK8	S35	T42M	42	Missense	distal	7	no	7.738	7.798	EPSD	TCGA;ICGC;COSMIC	2.638	Up-regulation
CMGC_MAPK_JNK_MAPK8_ST	Q8WYQ5	DGCR8	P45983	MAPK8	S95	R100W	100	Missense	distal	5	no	10.575	10.597	EPSD	TCGA;ICGC;COSMIC	2.638	Up-regulation
CMGC_MAPK_JNK_MAPK8_ST	Q8WYQ5	DGCR8	P45983	MAPK8	S95	S95I	95	Missense	central	0	yes	10.575	0.000	EPSD	TCGA;ICGC	2.638	Loss
CMGC_MAPK_JNK_MAPK8_ST	Q8WYQ5	DGCR8	P45983	MAPK8	S95	P89L	89	Missense	distal	-6	no	10.575	10.666	EPSD	TCGA;ICGC	2.638	Up-regulation
CMGC_MAPK_JNK_MAPK8_ST	Q8WYQ5	DGCR8	P45983	MAPK8	S95	S95N	95	Missense	central	0	yes	10.575	0.000	EPSD	TCGA;ICGC	2.638	Loss
CMGC_MAPK_JNK_MAPK8_ST	Q8WYQ5	DGCR8	P45983	MAPK8	S109	K116N	116	Missense	distal	7	no	6.871	6.955	EPSD	TCGA;ICGC	2.638	Up-regulation
CMGC_MAPK_JNK_MAPK8_ST	Q8WYQ5	DGCR8	P45983	MAPK8	S153	V159M	159	Missense	distal	6	no	7.348	7.364	PhosphoSitePlus	TCGA;ICGC;COSMIC	2.638	Up-regulation
CMGC_MAPK_JNK_MAPK8_ST	Q8WYQ5	DGCR8	P45983	MAPK8	S153	S156N	156	Missense	distal	3	no	7.348	7.552	PhosphoSitePlus	TCGA;ICGC;COSMIC	2.638	Up-regulation
CMGC_MAPK_JNK_MAPK8_ST	Q8WYQ5	DGCR8	P45983	MAPK8	S153	A146V	146	Missense	distal	-7	no	7.348	7.366	PhosphoSitePlus	TCGA;ICGC;COSMIC	2.638	Up-regulation
CMGC_MAPK_JNK_MAPK8_ST	Q8WYQ5	DGCR8	P45983	MAPK8	S153	G149C	149	Missense	distal	-4	no	7.348	7.469	PhosphoSitePlus	TCGA;ICGC;COSMIC	2.638	Up-regulation
CMGC_MAPK_JNK_MAPK8_ST	Q8WYQ5	DGCR8	P45983	MAPK8	T371	P378H	378	Missense	distal	7	no	6.340	6.354	EPSD	TCGA;ICGC;COSMIC	2.638	Up-regulation
CMGC_MAPK_JNK_MAPK8_ST	Q8WYQ5	DGCR8	P45983	MAPK8	T371	G374W	374	Missense	distal	3	no	6.340	6.382	EPSD	TCGA;ICGC;COSMIC	2.638	Up-regulation
CMGC_MAPK_JNK_MAPK8_ST	Q8WYQ5	DGCR8	P45983	MAPK8	S373	G374W	374	Missense	proximal	1	no	1.625	2.888	EPSD	TCGA;ICGC;COSMIC	2.638	Gain
CMGC_MAPK_JNK_MAPK8_ST	Q8WYQ5	DGCR8	P45983	MAPK8	S377	P378H	378	Missense	proximal	1	no	7.335	-0.581	EPSD	TCGA;ICGC;COSMIC	2.638	Loss
CMGC_MAPK_JNK_MAPK8_ST	Q8WYQ5	DGCR8	P45983	MAPK8	S377	G374W	374	Missense	distal	-3	no	7.335	7.226	EPSD	TCGA;ICGC;COSMIC	2.638	Down-regulation
CMGC_MAPK_JNK_MAPK8_ST	Q8WYQ5	DGCR8	P45983	MAPK8	S377	V379I	379	Missense	proximal	2	no	7.335	7.506	EPSD	TCGA;ICGC;COSMIC	2.638	Up-regulation
CMGC_MAPK_JNK_MAPK8_ST	Q8WYQ5	DGCR8	P45983	MAPK8	S619	S619F	619	Missense	central	0	yes	7.100	0.000	EPSD	TCGA;COSMIC	2.638	Loss
CMGC_MAPK_JNK_MAPK8_ST	Q8N122	RPTOR	P45983	MAPK8	S8	L10F	10	Missense	proximal	2	no	6.626	6.616	EPSD	TCGA;ICGC;COSMIC	2.638	Down-regulation
CMGC_MAPK_JNK_MAPK8_ST	Q8N122	RPTOR	P45983	MAPK8	S8	L11M	11	Missense	distal	3	no	6.626	6.604	EPSD	TCGA;ICGC;COSMIC	2.638	Down-regulation
CMGC_MAPK_JNK_MAPK8_ST	Q8N122	RPTOR	P45983	MAPK8	T706	C713F	713	Missense	distal	7	no	8.509	8.532	EPSD;PhosphoSitePlus	TCGA	2.638	Up-regulation
CMGC_MAPK_JNK_MAPK8_ST	Q8N122	RPTOR	P45983	MAPK8	T706	R709Q	709	Missense	distal	3	no	8.509	8.384	EPSD;PhosphoSitePlus	TCGA;COSMIC	2.638	Down-regulation
CMGC_MAPK_JNK_MAPK8_ST	Q8N122	RPTOR	P45983	MAPK8	S711	C713F	713	Missense	proximal	2	no	6.618	6.539	EPSD	TCGA	2.638	Down-regulation
CMGC_MAPK_JNK_MAPK8_ST	Q8N122	RPTOR	P45983	MAPK8	S711	R709Q	709	Missense	proximal	-2	no	6.618	6.692	EPSD	TCGA;COSMIC	2.638	Up-regulation
CMGC_MAPK_JNK_MAPK8_ST	Q8N122	RPTOR	P45983	MAPK8	T714	S719F	719	Missense	distal	5	no	8.846	8.922	EPSD	TCGA;ICGC;COSMIC	2.638	Up-regulation
CMGC_MAPK_JNK_MAPK8_ST	Q8N122	RPTOR	P45983	MAPK8	T714	C713F	713	Missense	proximal	-1	no	8.846	8.836	EPSD	TCGA	2.638	Down-regulation
CMGC_MAPK_JNK_MAPK8_ST	Q8N122	RPTOR	P45983	MAPK8	T714	R709Q	709	Missense	distal	-5	no	8.846	8.531	EPSD	TCGA;COSMIC	2.638	Down-regulation
CMGC_MAPK_JNK_MAPK8_ST	Q8N122	RPTOR	P45983	MAPK8	S771	E775K	775	Missense	distal	4	no	6.735	6.816	EPSD	TCGA;COSMIC	2.638	Up-regulation
CMGC_MAPK_JNK_MAPK8_ST	Q8N122	RPTOR	P45983	MAPK8	S836	V829L	829	Missense	distal	-7	no	3.092	3.090	EPSD	TCGA;COSMIC	2.638	Down-regulation
CMGC_MAPK_JNK_MAPK8_ST	Q8N122	RPTOR	P45983	MAPK8	S859	T857M	857	Missense	proximal	-2	no	4.390	4.274	EPSD	TCGA;COSMIC	2.638	Down-regulation
CMGC_MAPK_JNK_MAPK8_ST	Q8N122	RPTOR	P45983	MAPK8	S863	T857M	857	Missense	distal	-6	no	9.337	9.476	EPSD;PhosphoSitePlus	TCGA;COSMIC	2.638	Up-regulation
CMGC_MAPK_JNK_MAPK8_ST	Q8N122	RPTOR	P45983	MAPK8	S877	S877F	877	Missense	central	0	yes	9.094	0.000	EPSD	TCGA;COSMIC	2.638	Loss
CMGC_MAPK_JNK_MAPK8_ST	Q8N122	RPTOR	P45983	MAPK8	S877	P879L	879	Missense	proximal	2	no	9.094	9.017	EPSD	TCGA;COSMIC	2.638	Down-regulation
CMGC_MAPK_JNK_MAPK8_ST	Q8N122	RPTOR	P45983	MAPK8	S881	S877F	877	Missense	distal	-4	no	3.451	2.513	EPSD	TCGA;COSMIC	2.638	Loss
CMGC_MAPK_JNK_MAPK8_ST	Q8N122	RPTOR	P45983	MAPK8	S881	P879L	879	Missense	proximal	-2	no	3.451	3.258	EPSD	TCGA;COSMIC	2.638	Down-regulation
CMGC_MAPK_JNK_MAPK8_ST	Q8N122	RPTOR	P45983	MAPK8	S898	P896S	896	Missense	proximal	-2	no	3.303	3.198	EPSD	TCGA	2.638	Down-regulation
CMGC_MAPK_JNK_MAPK8_ST	Q8N122	RPTOR	P45983	MAPK8	S898	D891N	891	Missense	distal	-7	no	3.303	3.310	EPSD	TCGA;COSMIC	2.638	Up-regulation
CMGC_MAPK_JNK_MAPK8_ST	P04637	TP53	P45983	MAPK8	S20	P27S	27	Missense	distal	7	no	4.275	4.236	PhosphoSitePlus;EPSD	TCGA;ICGC;COSMIC	2.638	Down-regulation
CMGC_MAPK_JNK_MAPK8_ST	P04637	TP53	P45983	MAPK8	S20	P27L	27	Missense	distal	7	no	4.275	4.315	PhosphoSitePlus;EPSD	TCGA;ICGC;COSMIC;GDSC;CCLE	2.638	Up-regulation
CMGC_MAPK_JNK_MAPK8_ST	P04637	TP53	P45983	MAPK8	S33	P27S	27	Missense	distal	-6	no	7.176	7.087	EPSD	TCGA;ICGC;COSMIC	2.638	Down-regulation
CMGC_MAPK_JNK_MAPK8_ST	P04637	TP53	P45983	MAPK8	S33	P27L	27	Missense	distal	-6	no	7.176	7.267	EPSD	TCGA;ICGC;COSMIC;GDSC;CCLE	2.638	Up-regulation
CMGC_MAPK_JNK_MAPK8_ST	P04637	TP53	P45983	MAPK8	S46	D48N	48	Missense	proximal	2	no	8.038	7.913	EPSD	TCGA;ICGC;COSMIC;GDSC;CCLE	2.638	Down-regulation
CMGC_MAPK_JNK_MAPK8_ST	P04637	TP53	P45983	MAPK8	T81	A79V	79	Missense	proximal	-2	no	7.682	7.491	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	2.638	Down-regulation
CMGC_MAPK_JNK_MAPK8_ST	P04637	TP53	P45983	MAPK8	T81	P77L	77	Missense	distal	-4	no	7.682	7.356	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	2.638	Down-regulation
CMGC_MAPK_JNK_MAPK8_ST	P04637	TP53	P45983	MAPK8	T81	P82L	82	Missense	proximal	1	no	7.682	0.110	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	2.638	Loss
CMGC_MAPK_JNK_MAPK8_ST	P04637	TP53	P45983	MAPK8	T81	A74T	74	Missense	distal	-7	no	7.682	7.684	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	2.638	Up-regulation
CMGC_MAPK_JNK_MAPK8_ST	P04637	TP53	P45983	MAPK8	S127	K132N	132	Missense	distal	5	no	8.358	8.446	EPSD	TCGA;ICGC;COSMIC;GDSC;CCLE	2.638	Up-regulation
CMGC_MAPK_JNK_MAPK8_ST	P04637	TP53	P45983	MAPK8	S127	S121Y	121	Missense	distal	-6	no	8.358	8.590	EPSD	TCGA;ICGC;COSMIC	2.638	Up-regulation
CMGC_MAPK_JNK_MAPK8_ST	P04637	TP53	P45983	MAPK8	S127	M133K	133	Missense	distal	6	no	8.358	8.439	EPSD	TCGA;ICGC;COSMIC;CCLE	2.638	Up-regulation
CMGC_MAPK_JNK_MAPK8_ST	P04637	TP53	P45983	MAPK8	S127	K132E	132	Missense	distal	5	no	8.358	8.366	EPSD	TCGA;ICGC;COSMIC;GDSC;CCLE	2.638	Up-regulation
CMGC_MAPK_JNK_MAPK8_ST	P04637	TP53	P45983	MAPK8	S127	Y126C	126	Missense	proximal	-1	no	8.358	8.376	EPSD	TCGA;ICGC;COSMIC;GDSC	2.638	Up-regulation
CMGC_MAPK_JNK_MAPK8_ST	P04637	TP53	P45983	MAPK8	S127	S127P	127	Missense	central	0	yes	8.358	0.000	EPSD	TCGA;ICGC;COSMIC;GDSC;CCLE	2.638	Loss
CMGC_MAPK_JNK_MAPK8_ST	P04637	TP53	P45983	MAPK8	S127	Y126N	126	Missense	proximal	-1	no	8.358	8.367	EPSD	TCGA;ICGC;COSMIC	2.638	Up-regulation
CMGC_MAPK_JNK_MAPK8_ST	P04637	TP53	P45983	MAPK8	S127	L130V	130	Missense	distal	3	no	8.358	8.376	EPSD	TCGA;ICGC;COSMIC;GDSC;CCLE	2.638	Up-regulation
CMGC_MAPK_JNK_MAPK8_ST	P04637	TP53	P45983	MAPK8	S127	K132T	132	Missense	distal	5	no	8.358	8.383	EPSD	TCGA;ICGC;COSMIC;GDSC;CCLE	2.638	Up-regulation
CMGC_MAPK_JNK_MAPK8_ST	P04637	TP53	P45983	MAPK8	S127	S127Y	127	Missense	central	0	yes	8.358	0.000	EPSD	TCGA;ICGC;COSMIC	2.638	Loss
CMGC_MAPK_JNK_MAPK8_ST	P04637	TP53	P45983	MAPK8	S127	S127F	127	Missense	central	0	yes	8.358	0.000	EPSD	TCGA;ICGC;COSMIC;CCLE	2.638	Loss
CMGC_MAPK_JNK_MAPK8_ST	P04637	TP53	P45983	MAPK8	S127	M133R	133	Missense	distal	6	no	8.358	8.361	EPSD	TCGA;ICGC;COSMIC	2.638	Up-regulation
CMGC_MAPK_JNK_MAPK8_ST	P04637	TP53	P45983	MAPK8	S127	K132R	132	Missense	distal	5	no	8.358	8.449	EPSD	TCGA;ICGC;COSMIC;GDSC;CCLE	2.638	Up-regulation
CMGC_MAPK_JNK_MAPK8_ST	P04637	TP53	P45983	MAPK8	S127	F134L	134	Missense	distal	7	no	8.358	8.361	EPSD	TCGA;ICGC;COSMIC;CCLE	2.638	Up-regulation
CMGC_MAPK_JNK_MAPK8_ST	P04637	TP53	P45983	MAPK8	S127	Y126S	126	Missense	proximal	-1	no	8.358	8.395	EPSD	TCGA;ICGC;COSMIC	2.638	Up-regulation
CMGC_MAPK_JNK_MAPK8_ST	P04637	TP53	P45983	MAPK8	S127	L130P	130	Missense	distal	3	no	8.358	8.256	EPSD	TCGA;ICGC;COSMIC	2.638	Down-regulation
CMGC_MAPK_JNK_MAPK8_ST	P04637	TP53	P45983	MAPK8	S127	L130F	130	Missense	distal	3	no	8.358	8.350	EPSD	TCGA;ICGC;COSMIC;CCLE	2.638	Down-regulation
CMGC_MAPK_JNK_MAPK8_ST	P04637	TP53	P45983	MAPK8	S127	F134V	134	Missense	distal	7	no	8.358	8.367	EPSD	TCGA;ICGC;COSMIC	2.638	Up-regulation
CMGC_MAPK_JNK_MAPK8_ST	P04637	TP53	P45983	MAPK8	S127	T125M	125	Missense	proximal	-2	no	8.358	8.241	EPSD	TCGA;ICGC;COSMIC;GDSC	2.638	Down-regulation
CMGC_MAPK_JNK_MAPK8_ST	P04637	TP53	P45983	MAPK8	S127	Y126D	126	Missense	proximal	-1	no	8.358	8.382	EPSD	TCGA;ICGC;COSMIC;GDSC	2.638	Up-regulation
CMGC_MAPK_JNK_MAPK8_ST	P04637	TP53	P45983	MAPK8	S127	K120E	120	Missense	distal	-7	no	8.358	8.361	EPSD	TCGA;ICGC;COSMIC	2.638	Up-regulation
CMGC_MAPK_JNK_MAPK8_ST	P04637	TP53	P45983	MAPK8	S127	N131S	131	Missense	distal	4	no	8.358	8.806	EPSD	TCGA;ICGC;COSMIC	2.638	Up-regulation
CMGC_MAPK_JNK_MAPK8_ST	P04637	TP53	P45983	MAPK8	S127	T125P	125	Missense	proximal	-2	no	8.358	8.438	EPSD	TCGA;ICGC;COSMIC;CCLE	2.638	Up-regulation
CMGC_MAPK_JNK_MAPK8_ST	P04637	TP53	P45983	MAPK8	S127	S127C	127	Missense	central	0	yes	8.358	0.000	EPSD	TCGA;ICGC;COSMIC;CCLE	2.638	Loss
CMGC_MAPK_JNK_MAPK8_ST	P04637	TP53	P45983	MAPK8	S127	N131I	131	Missense	distal	4	no	8.358	8.616	EPSD	TCGA;ICGC;COSMIC	2.638	Up-regulation
CMGC_MAPK_JNK_MAPK8_ST	P04637	TP53	P45983	MAPK8	S127	Y126H	126	Missense	proximal	-1	no	8.358	8.375	EPSD	TCGA;ICGC;COSMIC;GDSC	2.638	Up-regulation
CMGC_MAPK_JNK_MAPK8_ST	P04637	TP53	P45983	MAPK8	S127	K132Q	132	Missense	distal	5	no	8.358	8.397	EPSD	TCGA;ICGC;COSMIC;GDSC;CCLE	2.638	Up-regulation
CMGC_MAPK_JNK_MAPK8_ST	P04637	TP53	P45983	MAPK8	S127	L130R	130	Missense	distal	3	no	8.358	8.313	EPSD	TCGA;ICGC;COSMIC;CCLE	2.638	Down-regulation
CMGC_MAPK_JNK_MAPK8_ST	P04637	TP53	P45983	MAPK8	T150	W146S	146	Missense	distal	-4	no	6.536	7.581	EPSD	TCGA;ICGC;COSMIC	2.638	Up-regulation
CMGC_MAPK_JNK_MAPK8_ST	P04637	TP53	P45983	MAPK8	T150	P152L	152	Missense	proximal	2	no	6.536	6.460	EPSD	TCGA;ICGC;COSMIC;GDSC;CCLE	2.638	Down-regulation
CMGC_MAPK_JNK_MAPK8_ST	P04637	TP53	P45983	MAPK8	T150	D148N	148	Missense	proximal	-2	no	6.536	6.439	EPSD	TCGA;ICGC;COSMIC	2.638	Down-regulation
CMGC_MAPK_JNK_MAPK8_ST	P04637	TP53	P45983	MAPK8	T150	P151H	151	Missense	proximal	1	no	6.536	-1.379	EPSD	TCGA;ICGC;COSMIC;GDSC;CCLE	2.638	Loss
CMGC_MAPK_JNK_MAPK8_ST	P04637	TP53	P45983	MAPK8	T150	P151A	151	Missense	proximal	1	no	6.536	0.189	EPSD	TCGA;ICGC;COSMIC;CCLE	2.638	Loss
CMGC_MAPK_JNK_MAPK8_ST	P04637	TP53	P45983	MAPK8	T150	R156P	156	Missense	distal	6	no	6.536	6.572	EPSD	TCGA;ICGC;COSMIC;GDSC;CCLE	2.638	Up-regulation
CMGC_MAPK_JNK_MAPK8_ST	P04637	TP53	P45983	MAPK8	T150	V143A	143	Missense	distal	-7	no	6.536	6.518	EPSD	TCGA;ICGC;COSMIC;GDSC;CCLE	2.638	Down-regulation
CMGC_MAPK_JNK_MAPK8_ST	P04637	TP53	P45983	MAPK8	T150	P151S	151	Missense	proximal	1	no	6.536	-1.192	EPSD	TCGA;ICGC;COSMIC;GDSC;CCLE	2.638	Loss
CMGC_MAPK_JNK_MAPK8_ST	P04637	TP53	P45983	MAPK8	T150	V157F	157	Missense	distal	7	no	6.536	6.527	EPSD	TCGA;ICGC;COSMIC;GDSC;CCLE	2.638	Down-regulation
CMGC_MAPK_JNK_MAPK8_ST	P04637	TP53	P45983	MAPK8	T150	V157G	157	Missense	distal	7	no	6.536	6.517	EPSD	TCGA;ICGC;COSMIC	2.638	Down-regulation
CMGC_MAPK_JNK_MAPK8_ST	P04637	TP53	P45983	MAPK8	T150	V157D	157	Missense	distal	7	no	6.536	6.492	EPSD	TCGA;ICGC;COSMIC	2.638	Down-regulation
CMGC_MAPK_JNK_MAPK8_ST	P04637	TP53	P45983	MAPK8	T150	L145R	145	Missense	distal	-5	no	6.536	6.469	EPSD	TCGA;ICGC;COSMIC;GDSC;CCLE	2.638	Down-regulation
CMGC_MAPK_JNK_MAPK8_ST	P04637	TP53	P45983	MAPK8	T150	T155I	155	Missense	distal	5	no	6.536	6.578	EPSD	TCGA;ICGC;COSMIC;CCLE	2.638	Up-regulation
CMGC_MAPK_JNK_MAPK8_ST	P04637	TP53	P45983	MAPK8	T150	V143M	143	Missense	distal	-7	no	6.536	6.533	EPSD	TCGA;ICGC;COSMIC;GDSC;CCLE	2.638	Down-regulation
CMGC_MAPK_JNK_MAPK8_ST	P04637	TP53	P45983	MAPK8	T150	T155N	155	Missense	distal	5	no	6.536	6.599	EPSD	TCGA;ICGC;COSMIC;GDSC;CCLE	2.638	Up-regulation
CMGC_MAPK_JNK_MAPK8_ST	P04637	TP53	P45983	MAPK8	T150	P152S	152	Missense	proximal	2	no	6.536	6.722	EPSD	TCGA;ICGC;COSMIC;CCLE	2.638	Up-regulation
CMGC_MAPK_JNK_MAPK8_ST	P04637	TP53	P45983	MAPK8	T150	R156C	156	Missense	distal	6	no	6.536	6.548	EPSD	TCGA;ICGC;COSMIC	2.638	Up-regulation
CMGC_MAPK_JNK_MAPK8_ST	P04637	TP53	P45983	MAPK8	T150	P151T	151	Missense	proximal	1	no	6.536	-0.450	EPSD	TCGA;ICGC;COSMIC	2.638	Loss
CMGC_MAPK_JNK_MAPK8_ST	P04637	TP53	P45983	MAPK8	T150	T155P	155	Missense	distal	5	no	6.536	6.613	EPSD	TCGA;ICGC;COSMIC;CCLE	2.638	Up-regulation
CMGC_MAPK_JNK_MAPK8_ST	P04637	TP53	P45983	MAPK8	T150	V143G	143	Missense	distal	-7	no	6.536	6.531	EPSD	TCGA;ICGC;COSMIC	2.638	Down-regulation
CMGC_MAPK_JNK_MAPK8_ST	P04637	TP53	P45983	MAPK8	T150	P152Q	152	Missense	proximal	2	no	6.536	6.655	EPSD	TCGA;ICGC;COSMIC	2.638	Up-regulation
CMGC_MAPK_JNK_MAPK8_ST	P04637	TP53	P45983	MAPK8	T150	R156H	156	Missense	distal	6	no	6.536	6.549	EPSD	TCGA;ICGC;COSMIC	2.638	Up-regulation
CMGC_MAPK_JNK_MAPK8_ST	P04637	TP53	P45983	MAPK8	T150	L145P	145	Missense	distal	-5	no	6.536	6.176	EPSD	TCGA;ICGC;COSMIC	2.638	Down-regulation
CMGC_MAPK_JNK_MAPK8_ST	P04637	TP53	P45983	MAPK8	T150	Q144L	144	Missense	distal	-6	no	6.536	6.663	EPSD	TCGA;ICGC;COSMIC	2.638	Up-regulation
CMGC_MAPK_JNK_MAPK8_ST	P04637	TP53	P45983	MAPK8	T150	Q144H	144	Missense	distal	-6	no	6.536	6.616	EPSD	TCGA;ICGC;COSMIC	2.638	Up-regulation
CMGC_MAPK_JNK_MAPK8_ST	P04637	TP53	P45983	MAPK8	T150	G154V	154	Missense	distal	4	no	6.536	6.361	EPSD	TCGA;ICGC;COSMIC;GDSC;CCLE	2.638	Down-regulation
CMGC_MAPK_JNK_MAPK8_ST	P04637	TP53	P45983	MAPK8	T150	V157L	157	Missense	distal	7	no	6.536	6.530	EPSD	TCGA;ICGC;COSMIC	2.638	Down-regulation
CMGC_MAPK_JNK_MAPK8_ST	P04637	TP53	P45983	MAPK8	T150	P151R	151	Missense	proximal	1	no	6.536	-0.600	EPSD	TCGA;ICGC;COSMIC	2.638	Loss
CMGC_MAPK_JNK_MAPK8_ST	P04637	TP53	P45983	MAPK8	T150	Q144P	144	Missense	distal	-6	no	6.536	6.572	EPSD	TCGA;ICGC;COSMIC	2.638	Up-regulation
CMGC_MAPK_JNK_MAPK8_ST	P04637	TP53	P45983	MAPK8	T150	V143E	143	Missense	distal	-7	no	6.536	6.518	EPSD	TCGA;ICGC;COSMIC	2.638	Down-regulation
CMGC_MAPK_JNK_MAPK8_ST	P04637	TP53	P45983	MAPK8	T150	R156G	156	Missense	distal	6	no	6.536	6.540	EPSD	TCGA;ICGC;COSMIC	2.638	Up-regulation
CMGC_MAPK_JNK_MAPK8_ST	P04637	TP53	P45983	MAPK8	T150	P151L	151	Missense	proximal	1	no	6.536	-1.036	EPSD	TCGA;ICGC;COSMIC	2.638	Loss
CMGC_MAPK_JNK_MAPK8_ST	P04637	TP53	P45983	MAPK8	T155	R156P	156	Missense	proximal	1	no	-1.170	5.967	EPSD	TCGA;ICGC;COSMIC;GDSC;CCLE	2.638	Gain
CMGC_MAPK_JNK_MAPK8_ST	P04637	TP53	P45983	MAPK8	S183	H179R	179	Missense	distal	-4	no	3.143	3.085	EPSD	TCGA;ICGC;COSMIC;GDSC;CCLE	2.638	Down-regulation
CMGC_MAPK_JNK_MAPK8_ST	P04637	TP53	P45983	MAPK8	S183	C176F	176	Missense	distal	-7	no	3.143	3.148	EPSD	TCGA;ICGC;COSMIC;GDSC;CCLE	2.638	Up-regulation
CMGC_MAPK_JNK_MAPK8_ST	P04637	TP53	P45983	MAPK8	S183	G187S	187	Missense	distal	4	no	3.143	3.487	EPSD	TCGA;ICGC;COSMIC	2.638	Up-regulation
CMGC_MAPK_JNK_MAPK8_ST	P04637	TP53	P45983	MAPK8	S183	H179Y	179	Missense	distal	-4	no	3.143	2.653	EPSD	TCGA;ICGC;COSMIC	2.638	Down-regulation
CMGC_MAPK_JNK_MAPK8_ST	P04637	TP53	P45983	MAPK8	S183	C176Y	176	Missense	distal	-7	no	3.143	3.153	EPSD	TCGA;ICGC;COSMIC;GDSC;CCLE	2.638	Up-regulation
CMGC_MAPK_JNK_MAPK8_ST	P04637	TP53	P45983	MAPK8	S183	P190L	190	Missense	distal	7	no	3.143	3.183	EPSD	TCGA;ICGC;COSMIC;CCLE	2.638	Up-regulation
CMGC_MAPK_JNK_MAPK8_ST	P04637	TP53	P45983	MAPK8	S183	P177S	177	Missense	distal	-6	no	3.143	3.054	EPSD	TCGA;ICGC;COSMIC	2.638	Down-regulation
CMGC_MAPK_JNK_MAPK8_ST	P04637	TP53	P45983	MAPK8	S183	H178Q	178	Missense	distal	-5	no	3.143	2.924	EPSD	TCGA;ICGC;COSMIC	2.638	Down-regulation
CMGC_MAPK_JNK_MAPK8_ST	P04637	TP53	P45983	MAPK8	S183	E180K	180	Missense	distal	-3	no	3.143	3.170	EPSD	TCGA;ICGC;COSMIC;CCLE	2.638	Up-regulation
CMGC_MAPK_JNK_MAPK8_ST	P04637	TP53	P45983	MAPK8	S183	C176S	176	Missense	distal	-7	no	3.143	3.132	EPSD	TCGA;ICGC;COSMIC;GDSC;CCLE	2.638	Down-regulation
CMGC_MAPK_JNK_MAPK8_ST	P04637	TP53	P45983	MAPK8	S183	H179N	179	Missense	distal	-4	no	3.143	3.013	EPSD	TCGA;ICGC;COSMIC	2.638	Down-regulation
CMGC_MAPK_JNK_MAPK8_ST	P04637	TP53	P45983	MAPK8	S183	H179P	179	Missense	distal	-4	no	3.143	3.222	EPSD	TCGA;ICGC;COSMIC	2.638	Up-regulation
CMGC_MAPK_JNK_MAPK8_ST	P04637	TP53	P45983	MAPK8	S183	H179L	179	Missense	distal	-4	no	3.143	2.895	EPSD	TCGA;ICGC;COSMIC	2.638	Down-regulation
CMGC_MAPK_JNK_MAPK8_ST	P04637	TP53	P45983	MAPK8	S183	H179D	179	Missense	distal	-4	no	3.143	3.320	EPSD	TCGA;ICGC;COSMIC;GDSC;CCLE	2.638	Up-regulation
CMGC_MAPK_JNK_MAPK8_ST	P04637	TP53	P45983	MAPK8	S183	P190R	190	Missense	distal	7	no	3.143	3.168	EPSD	TCGA;ICGC;COSMIC	2.638	Up-regulation
CMGC_MAPK_JNK_MAPK8_ST	P04637	TP53	P45983	MAPK8	S183	P177R	177	Missense	distal	-6	no	3.143	3.209	EPSD	TCGA;ICGC;COSMIC	2.638	Up-regulation
CMGC_MAPK_JNK_MAPK8_ST	P04637	TP53	P45983	MAPK8	S183	P177H	177	Missense	distal	-6	no	3.143	3.188	EPSD	TCGA;ICGC;COSMIC	2.638	Up-regulation
CMGC_MAPK_JNK_MAPK8_ST	P04637	TP53	P45983	MAPK8	S183	C176W	176	Missense	distal	-7	no	3.143	3.149	EPSD	TCGA;ICGC;COSMIC;GDSC;CCLE	2.638	Up-regulation
CMGC_MAPK_JNK_MAPK8_ST	P04637	TP53	P45983	MAPK8	S183	H179Q	179	Missense	distal	-4	no	3.143	3.606	EPSD	TCGA;ICGC;COSMIC;GDSC;CCLE	2.638	Up-regulation
CMGC_MAPK_JNK_MAPK8_ST	P04637	TP53	P45983	MAPK8	S183	P177T	177	Missense	distal	-6	no	3.143	3.080	EPSD	TCGA;ICGC;COSMIC;GDSC;CCLE	2.638	Down-regulation
CMGC_MAPK_JNK_MAPK8_ST	P04637	TP53	P45983	MAPK8	S183	R181P	181	Missense	proximal	-2	no	3.143	3.327	EPSD	TCGA;ICGC;COSMIC;CCLE	2.638	Up-regulation
CMGC_MAPK_JNK_MAPK8_ST	P04637	TP53	P45983	MAPK8	S183	C176R	176	Missense	distal	-7	no	3.143	3.145	EPSD	TCGA;ICGC;COSMIC	2.638	Up-regulation
CMGC_MAPK_JNK_MAPK8_ST	P04637	TP53	P45983	MAPK8	S183	R181C	181	Missense	proximal	-2	no	3.143	3.157	EPSD	TCGA;ICGC;COSMIC;GDSC;CCLE	2.638	Up-regulation
CMGC_MAPK_JNK_MAPK8_ST	P04637	TP53	P45983	MAPK8	S183	P177L	177	Missense	distal	-6	no	3.143	3.235	EPSD	TCGA;ICGC;COSMIC;GDSC;CCLE	2.638	Up-regulation
CMGC_MAPK_JNK_MAPK8_ST	P04637	TP53	P45983	MAPK8	S315	K319N	319	Missense	distal	4	no	8.332	7.853	EPSD	TCGA;ICGC;COSMIC	2.638	Down-regulation
CMGC_MAPK_JNK_MAPK8_ST	P04637	TP53	P45983	MAPK8	S315	K320E	320	Missense	distal	5	no	8.332	8.340	EPSD	TCGA;ICGC;COSMIC	2.638	Up-regulation
CMGC_MAPK_JNK_MAPK8_ST	P04637	TP53	P45983	MAPK8	S315	S315C	315	Missense	central	0	yes	8.332	0.000	EPSD	TCGA;ICGC;COSMIC	2.638	Loss
CMGC_MAPK_JNK_MAPK8_ST	Q96FI4	NEIL1	P45983	MAPK8	S61	E55K	55	Missense	distal	-6	no	8.363	8.358	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	2.638	Down-regulation
CMGC_MAPK_JNK_MAPK8_ST	Q96FI4	NEIL1	P45983	MAPK8	S61	G65V	65	Missense	distal	4	no	8.363	8.187	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	2.638	Down-regulation
CMGC_MAPK_JNK_MAPK8_ST	P37231	PPARG	P45983	MAPK8	S112	S117Y	117	Missense	distal	5	no	8.805	8.912	PhosphoSitePlus	TCGA	2.638	Up-regulation
CMGC_MAPK_JNK_MAPK8_ST	P37231	PPARG	P45983	MAPK8	S273	M280T	280	Missense	distal	7	no	7.718	7.658	EPSD	TCGA;COSMIC	2.638	Down-regulation
CMGC_MAPK_JNK_MAPK8_ST	P37231	PPARG	P45983	MAPK8	S273	G267E	267	Missense	distal	-6	no	7.718	7.560	EPSD	TCGA	2.638	Down-regulation
CMGC_MAPK_JNK_MAPK8_ST	P29966	MARCKS	P45983	MAPK8	S27	P28L	28	Missense	proximal	1	no	9.143	1.570	EPSD	TCGA;ICGC;COSMIC	2.638	Loss
CMGC_MAPK_JNK_MAPK8_ST	P29966	MARCKS	P45983	MAPK8	S27	S29F	29	Missense	proximal	2	no	9.143	8.871	EPSD	TCGA;ICGC;COSMIC	2.638	Down-regulation
CMGC_MAPK_JNK_MAPK8_ST	Q8N6T7	SIRT6	P45983	MAPK8	T294	R291C	291	Missense	distal	-3	no	9.150	9.199	EPSD	TCGA;ICGC;COSMIC	2.638	Up-regulation
CMGC_MAPK_JNK_MAPK8_ST	Q8N6T7	SIRT6	P45983	MAPK8	S303	S303Y	303	Missense	central	0	yes	7.344	0.000	EPSD	TCGA;ICGC	2.638	Loss
CMGC_MAPK_JNK_MAPK8_ST	Q8N6T7	SIRT6	P45983	MAPK8	S330	A329V	329	Missense	proximal	-1	no	9.096	9.060	EPSD	TCGA;ICGC;COSMIC	2.638	Down-regulation
CMGC_MAPK_JNK_MAPK8_ST	Q96LC9	BMF	P45983	MAPK8	T72	L73I	73	Missense	proximal	1	no	2.877	4.576	EPSD	TCGA;ICGC;COSMIC	2.638	Up-regulation
CMGC_MAPK_JNK_MAPK8_ST	Q96LC9	BMF	P45983	MAPK8	S74	L73I	73	Missense	proximal	-1	no	7.205	7.221	PhosphoSitePlus	TCGA;ICGC;COSMIC	2.638	Up-regulation
CMGC_MAPK_JNK_MAPK8_ST	Q96LC9	BMF	P45983	MAPK8	S77	L73I	73	Missense	distal	-4	no	8.228	8.579	EPSD	TCGA;ICGC;COSMIC	2.638	Up-regulation
CMGC_MAPK_JNK_MAPK8_ST	Q7KZF4	SND1	P45983	MAPK8	T98	T98M	98	Missense	central	0	yes	3.055	0.000	EPSD	TCGA;ICGC;COSMIC	2.638	Loss
CMGC_MAPK_JNK_MAPK8_ST	Q7KZF4	SND1	P45983	MAPK8	T103	T98M	98	Missense	distal	-5	no	8.214	8.655	PhosphoSitePlus	TCGA;ICGC;COSMIC	2.638	Up-regulation
CMGC_MAPK_JNK_MAPK8_ST	Q7KZF4	SND1	P45983	MAPK8	T179	E181Q	181	Missense	proximal	2	no	3.146	3.016	EPSD	TCGA;ICGC;COSMIC	2.638	Down-regulation
CMGC_MAPK_JNK_MAPK8_ST	Q7KZF4	SND1	P45983	MAPK8	S189	H190P	190	Missense	proximal	1	no	-0.153	7.763	EPSD	TCGA;ICGC	2.638	Gain
CMGC_MAPK_JNK_MAPK8_ST	Q7KZF4	SND1	P45983	MAPK8	T240	R233W	233	Missense	distal	-7	no	7.851	7.854	EPSD	TCGA;ICGC;COSMIC	2.638	Up-regulation
CMGC_MAPK_JNK_MAPK8_ST	Q7KZF4	SND1	P45983	MAPK8	T240	F244S	244	Missense	distal	4	no	7.851	8.309	EPSD	TCGA;ICGC;COSMIC	2.638	Up-regulation
CMGC_MAPK_JNK_MAPK8_ST	Q7KZF4	SND1	P45983	MAPK8	T240	P241L	241	Missense	proximal	1	no	7.851	0.278	EPSD	TCGA;ICGC;COSMIC	2.638	Loss
CMGC_MAPK_JNK_MAPK8_ST	Q7KZF4	SND1	P45983	MAPK8	S426	P424S	424	Missense	proximal	-2	no	9.196	9.090	EPSD	TCGA;ICGC;COSMIC	2.638	Down-regulation
CMGC_MAPK_JNK_MAPK8_ST	Q7KZF4	SND1	P45983	MAPK8	S645	A646V	646	Missense	proximal	1	no	2.761	0.364	EPSD	TCGA;ICGC;COSMIC	2.638	Loss
CMGC_MAPK_JNK_MAPK8_ST	Q7KZF4	SND1	P45983	MAPK8	S681	V687G	687	Missense	distal	6	no	3.232	3.254	EPSD	TCGA;ICGC	2.638	Up-regulation
CMGC_MAPK_JNK_MAPK8_ST	Q7KZF4	SND1	P45983	MAPK8	S781	R776H	776	Missense	distal	-5	no	8.561	8.465	EPSD	TCGA;ICGC;COSMIC	2.638	Down-regulation
CMGC_MAPK_JNK_MAPK8_ST	Q7KZF4	SND1	P45983	MAPK8	S781	L780I	780	Missense	proximal	-1	no	8.561	8.578	EPSD	TCGA;ICGC	2.638	Up-regulation
CMGC_MAPK_JNK_MAPK8_ST	Q7KZF4	SND1	P45983	MAPK8	S781	R787W	787	Missense	distal	6	no	8.561	8.551	EPSD	TCGA;ICGC	2.638	Down-regulation
CMGC_MAPK_JNK_MAPK8_ST	P05787	KRT8	P45983	MAPK8	S13	S15F	15	Missense	proximal	2	no	2.739	2.467	EPSD	TCGA;ICGC;COSMIC	2.638	Loss
CMGC_MAPK_JNK_MAPK8_ST	P05787	KRT8	P45983	MAPK8	S432	S438G	438	Missense	distal	6	no	7.697	7.641	EPSD;PhosphoSitePlus	TCGA;COSMIC	2.638	Down-regulation
CMGC_MAPK_JNK_MAPK8_ST	P11802	CDK4	P45983	MAPK8	S166	R163K	163	Missense	distal	-3	no	3.246	3.629	EPSD	TCGA;COSMIC	2.638	Up-regulation
CMGC_MAPK_JNK_MAPK8_ST	P14618	PKM	P45983	MAPK8	S37	R43P	43	Missense	distal	6	no	7.425	7.461	EPSD	TCGA;ICGC;COSMIC	2.638	Up-regulation
CMGC_MAPK_JNK_MAPK8_ST	P14618	PKM	P45983	MAPK8	S37	R32C	32	Missense	distal	-5	no	7.425	7.326	EPSD	TCGA;ICGC;COSMIC	2.638	Down-regulation
CMGC_MAPK_JNK_MAPK8_ST	P14618	PKM	P45983	MAPK8	S37	R32H	32	Missense	distal	-5	no	7.425	7.330	EPSD	TCGA;ICGC;COSMIC	2.638	Down-regulation
CMGC_MAPK_JNK_MAPK8_ST	P14618	PKM	P45983	MAPK8	T41	R43P	43	Missense	proximal	2	no	3.502	3.558	EPSD	TCGA;ICGC;COSMIC	2.638	Up-regulation
CMGC_MAPK_JNK_MAPK8_ST	P14618	PKM	P45983	MAPK8	T41	G46V	46	Missense	distal	5	no	3.502	3.515	EPSD	TCGA;ICGC;COSMIC	2.638	Up-regulation
CMGC_MAPK_JNK_MAPK8_ST	P14618	PKM	P45983	MAPK8	T93	V91M	91	Missense	proximal	-2	no	2.605	2.650	EPSD	TCGA;ICGC;COSMIC	2.638	Gain
CMGC_MAPK_JNK_MAPK8_ST	P14618	PKM	P45983	MAPK8	T143	L144P	144	Missense	proximal	1	no	0.519	8.092	EPSD	TCGA;ICGC;COSMIC	2.638	Gain
CMGC_MAPK_JNK_MAPK8_ST	P14618	PKM	P45983	MAPK8	S346	R339H	339	Missense	distal	-7	no	2.917	2.915	EPSD	TCGA;COSMIC	2.638	Down-regulation
CMGC_MAPK_JNK_MAPK8_ST	P14618	PKM	P45983	MAPK8	S346	R342L	342	Missense	distal	-4	no	2.917	2.727	EPSD	TCGA;COSMIC	2.638	Down-regulation
CMGC_MAPK_JNK_MAPK8_ST	P14618	PKM	P45983	MAPK8	S346	N350S	350	Missense	distal	4	no	2.917	3.365	EPSD	TCGA;COSMIC	2.638	Up-regulation
CMGC_MAPK_JNK_MAPK8_ST	P14618	PKM	P45983	MAPK8	S346	R342W	342	Missense	distal	-4	no	2.917	2.674	EPSD	TCGA;COSMIC	2.638	Down-regulation
CMGC_MAPK_JNK_MAPK8_ST	P14618	PKM	P45983	MAPK8	T365	G368R	368	Missense	distal	3	no	3.414	3.406	PhosphoSitePlus	TCGA;COSMIC	2.638	Down-regulation
CMGC_MAPK_JNK_MAPK8_ST	P14618	PKM	P45983	MAPK8	S406	R400Q	400	Missense	distal	-6	no	4.057	3.955	EPSD	TCGA	2.638	Down-regulation
CMGC_MAPK_JNK_MAPK8_ST	Q93045	STMN2	P45983	MAPK8	S62	E55Q	55	Missense	distal	-7	no	8.093	8.097	EPSD	TCGA	2.638	Up-regulation
CMGC_MAPK_JNK_MAPK8_ST	Q93045	STMN2	P45983	MAPK8	S62	P63H	63	Missense	proximal	1	no	8.093	0.178	EPSD	TCGA;ICGC;COSMIC	2.638	Loss
CMGC_MAPK_JNK_MAPK8_ST	Q93045	STMN2	P45983	MAPK8	S62	L58F	58	Missense	distal	-4	no	8.093	8.147	EPSD	TCGA;ICGC;COSMIC	2.638	Up-regulation
CMGC_MAPK_JNK_MAPK8_ST	Q93045	STMN2	P45983	MAPK8	S62	S65L	65	Missense	distal	3	no	8.093	8.321	EPSD	TCGA;ICGC;COSMIC	2.638	Up-regulation
CMGC_MAPK_JNK_MAPK8_ST	Q93045	STMN2	P45983	MAPK8	S62	E66D	66	Missense	distal	4	no	8.093	7.942	EPSD	TCGA;ICGC;COSMIC	2.638	Down-regulation
CMGC_MAPK_JNK_MAPK8_ST	Q93045	STMN2	P45983	MAPK8	S62	A67T	67	Missense	distal	5	no	8.093	8.091	EPSD	TCGA;ICGC;COSMIC	2.638	Down-regulation
CMGC_MAPK_JNK_MAPK8_ST	Q93045	STMN2	P45983	MAPK8	S73	S80F	80	Missense	distal	7	no	7.616	7.691	PhosphoSitePlus	TCGA;ICGC;COSMIC	2.638	Up-regulation
CMGC_MAPK_JNK_MAPK8_ST	Q93045	STMN2	P45983	MAPK8	S73	L71S	71	Missense	proximal	-2	no	7.616	7.703	PhosphoSitePlus	TCGA;ICGC;COSMIC	2.638	Up-regulation
CMGC_MAPK_JNK_MAPK8_ST	Q93045	STMN2	P45983	MAPK8	S73	E66D	66	Missense	distal	-7	no	7.616	7.625	PhosphoSitePlus	TCGA;ICGC;COSMIC	2.638	Up-regulation
CMGC_MAPK_JNK_MAPK8_ST	Q93045	STMN2	P45983	MAPK8	S73	A67T	67	Missense	distal	-6	no	7.616	7.638	PhosphoSitePlus	TCGA;ICGC;COSMIC	2.638	Up-regulation
CMGC_MAPK_JNK_MAPK8_ST	Q96P20	NLRP3	P45983	MAPK8	S198	S198R	198	Missense	central	0	yes	9.275	0.000	PhosphoSitePlus	TCGA;ICGC;COSMIC	2.638	Loss
CMGC_MAPK_JNK_MAPK8_ST	Q96P20	NLRP3	P45983	MAPK8	S198	I203T	203	Missense	distal	5	no	9.275	9.233	PhosphoSitePlus	TCGA;ICGC	2.638	Down-regulation
CMGC_MAPK_JNK_MAPK8_ST	Q96P20	NLRP3	P45983	MAPK8	S198	T195R	195	Missense	distal	-3	no	9.275	8.988	PhosphoSitePlus	TCGA;ICGC;COSMIC	2.638	Down-regulation
CMGC_MAPK_JNK_MAPK8_ST	Q96P20	NLRP3	P45983	MAPK8	S198	G191S	191	Missense	distal	-7	no	9.275	9.261	PhosphoSitePlus	TCGA;ICGC;COSMIC	2.638	Down-regulation
CMGC_MAPK_JNK_MAPK8_ST	Q96P20	NLRP3	P45983	MAPK8	S387	A394S	394	Missense	distal	7	no	2.719	2.714	EPSD	TCGA;ICGC;COSMIC	2.638	Down-regulation
CMGC_MAPK_JNK_MAPK8_ST	Q96P20	NLRP3	P45983	MAPK8	S387	Q391K	391	Missense	distal	4	no	2.719	2.881	EPSD	TCGA;ICGC;COSMIC	2.638	Up-regulation
CMGC_MAPK_JNK_MAPK8_ST	Q96P20	NLRP3	P45983	MAPK8	S387	A392D	392	Missense	distal	5	no	2.719	2.758	EPSD	TCGA;ICGC;COSMIC	2.638	Up-regulation
CMGC_MAPK_JNK_MAPK8_ST	Q96P20	NLRP3	P45983	MAPK8	S387	F382L	382	Missense	distal	-5	no	2.719	2.723	EPSD	TCGA;ICGC	2.638	Up-regulation
CMGC_MAPK_JNK_MAPK8_ST	P10275	AR	P45983	MAPK8	S96	G95S	95	Missense	proximal	-1	no	7.626	7.650	EPSD	TCGA;ICGC;COSMIC	2.638	Up-regulation
CMGC_MAPK_JNK_MAPK8_ST	P10275	AR	P45983	MAPK8	S96	E93D	93	Missense	distal	-3	no	7.626	7.387	EPSD	TCGA;ICGC;COSMIC	2.638	Down-regulation
CMGC_MAPK_JNK_MAPK8_ST	P10275	AR	P45983	MAPK8	S233	E238K	238	Missense	distal	5	no	2.978	2.970	EPSD	TCGA;ICGC;COSMIC	2.638	Down-regulation
CMGC_MAPK_JNK_MAPK8_ST	P10275	AR	P45983	MAPK8	S233	K237R	237	Missense	distal	4	no	2.978	2.583	EPSD	TCGA;ICGC;COSMIC	2.638	Loss
CMGC_MAPK_JNK_MAPK8_ST	P10275	AR	P45983	MAPK8	S258	R264W	264	Missense	distal	6	no	7.842	7.833	EPSD	TCGA;ICGC;COSMIC	2.638	Down-regulation
CMGC_MAPK_JNK_MAPK8_ST	P10275	AR	P45983	MAPK8	S258	A253V	253	Missense	distal	-5	no	7.842	8.383	EPSD	TCGA;ICGC;COSMIC	2.638	Up-regulation
CMGC_MAPK_JNK_MAPK8_ST	P10275	AR	P45983	MAPK8	T282	E289K	289	Missense	distal	7	no	7.473	7.458	EPSD	TCGA;ICGC;COSMIC	2.638	Down-regulation
CMGC_MAPK_JNK_MAPK8_ST	P10275	AR	P45983	MAPK8	T282	R280C	280	Missense	proximal	-2	no	7.473	7.487	EPSD	TCGA;ICGC;COSMIC	2.638	Up-regulation
CMGC_MAPK_JNK_MAPK8_ST	P10275	AR	P45983	MAPK8	S302	E308K	308	Missense	distal	6	no	3.833	3.849	EPSD	TCGA;COSMIC	2.638	Up-regulation
CMGC_MAPK_JNK_MAPK8_ST	P10275	AR	P45983	MAPK8	S302	A299T	299	Missense	distal	-3	no	3.833	3.779	EPSD	TCGA;ICGC;COSMIC	2.638	Down-regulation
CMGC_MAPK_JNK_MAPK8_ST	P10275	AR	P45983	MAPK8	S302	D297N	297	Missense	distal	-5	no	3.833	4.040	EPSD	TCGA;ICGC;COSMIC	2.638	Up-regulation
CMGC_MAPK_JNK_MAPK8_ST	P10275	AR	P45983	MAPK8	S310	E308K	308	Missense	proximal	-2	no	10.471	10.468	EPSD	TCGA;COSMIC	2.638	Down-regulation
CMGC_MAPK_JNK_MAPK8_ST	P10275	AR	P45983	MAPK8	S310	Y316H	316	Missense	distal	6	no	10.471	10.509	EPSD	TCGA;ICGC	2.638	Up-regulation
CMGC_MAPK_JNK_MAPK8_ST	P10275	AR	P45983	MAPK8	S330	G326S	326	Missense	distal	-4	no	2.512	3.400	EPSD	TCGA;ICGC	2.638	Gain
CMGC_MAPK_JNK_MAPK8_ST	P10275	AR	P45983	MAPK8	S516	P513S	513	Missense	distal	-3	no	7.555	7.717	EPSD	TCGA;ICGC;COSMIC	2.638	Up-regulation
CMGC_MAPK_JNK_MAPK8_ST	P10275	AR	P45983	MAPK8	S651	E645K	645	Missense	distal	-6	no	8.526	8.521	PhosphoSitePlus	TCGA;ICGC;COSMIC	2.638	Down-regulation
CMGC_MAPK_JNK_MAPK8_ST	P35568	IRS1	P45983	MAPK8	S307	A314G	314	Missense	distal	7	no	4.798	4.858	EPSD	TCGA;ICGC;COSMIC	2.638	Up-regulation
CMGC_MAPK_JNK_MAPK8_ST	P35568	IRS1	P45983	MAPK8	T309	A314G	314	Missense	distal	5	no	2.934	2.994	EPSD	TCGA;ICGC;COSMIC	2.638	Up-regulation
CMGC_MAPK_JNK_MAPK8_ST	P35568	IRS1	P45983	MAPK8	S312	A314G	314	Missense	proximal	2	no	8.564	8.338	PhosphoSitePlus	TCGA;ICGC;COSMIC	2.638	Down-regulation
CMGC_MAPK_JNK_MAPK8_ST	P35568	IRS1	P45983	MAPK8	S345	R338H	338	Missense	distal	-7	no	6.753	6.751	EPSD	TCGA;ICGC;COSMIC	2.638	Down-regulation
CMGC_MAPK_JNK_MAPK8_ST	P35568	IRS1	P45983	MAPK8	S345	R338C	338	Missense	distal	-7	no	6.753	6.751	EPSD	TCGA;ICGC;COSMIC	2.638	Down-regulation
CMGC_MAPK_JNK_MAPK8_ST	P35568	IRS1	P45983	MAPK8	S345	P346H	346	Missense	proximal	1	no	6.753	-1.162	EPSD	TCGA;ICGC	2.638	Loss
CMGC_MAPK_JNK_MAPK8_ST	P35568	IRS1	P45983	MAPK8	S348	P346H	346	Missense	proximal	-2	no	8.627	8.443	EPSD	TCGA;ICGC	2.638	Down-regulation
CMGC_MAPK_JNK_MAPK8_ST	P35568	IRS1	P45983	MAPK8	S383	P389L	389	Missense	distal	6	no	7.254	7.208	EPSD	TCGA;ICGC;COSMIC	2.638	Down-regulation
CMGC_MAPK_JNK_MAPK8_ST	P35568	IRS1	P45983	MAPK8	S383	P384H	384	Missense	proximal	1	no	7.254	-0.661	EPSD	TCGA;ICGC;COSMIC	2.638	Loss
CMGC_MAPK_JNK_MAPK8_ST	P35568	IRS1	P45983	MAPK8	S383	P378S	378	Missense	distal	-5	no	7.254	7.143	EPSD	TCGA;ICGC;COSMIC	2.638	Down-regulation
CMGC_MAPK_JNK_MAPK8_ST	P35568	IRS1	P45983	MAPK8	S388	P389L	389	Missense	proximal	1	no	6.604	-0.968	EPSD	TCGA;ICGC;COSMIC	2.638	Loss
CMGC_MAPK_JNK_MAPK8_ST	P35568	IRS1	P45983	MAPK8	S388	R381H	381	Missense	distal	-7	no	6.604	6.602	EPSD	TCGA	2.638	Down-regulation
CMGC_MAPK_JNK_MAPK8_ST	P35568	IRS1	P45983	MAPK8	S388	S395C	395	Missense	distal	7	no	6.604	6.657	EPSD	TCGA;ICGC;COSMIC	2.638	Up-regulation
CMGC_MAPK_JNK_MAPK8_ST	P35568	IRS1	P45983	MAPK8	S388	P384H	384	Missense	distal	-4	no	6.604	6.526	EPSD	TCGA;ICGC;COSMIC	2.638	Down-regulation
CMGC_MAPK_JNK_MAPK8_ST	P35568	IRS1	P45983	MAPK8	S413	R411Q	411	Missense	proximal	-2	no	3.042	3.116	EPSD	TCGA;ICGC	2.638	Up-regulation
CMGC_MAPK_JNK_MAPK8_ST	P35568	IRS1	P45983	MAPK8	S419	G424S	424	Missense	distal	5	no	7.849	7.781	EPSD	TCGA;ICGC;COSMIC	2.638	Down-regulation
CMGC_MAPK_JNK_MAPK8_ST	P35568	IRS1	P45983	MAPK8	S421	S428L	428	Missense	distal	7	no	2.747	2.825	EPSD	TCGA;ICGC;COSMIC	2.638	Up-regulation
CMGC_MAPK_JNK_MAPK8_ST	P35568	IRS1	P45983	MAPK8	S421	G424S	424	Missense	distal	3	no	2.747	2.557	EPSD	TCGA;ICGC;COSMIC	2.638	Loss
CMGC_MAPK_JNK_MAPK8_ST	P35568	IRS1	P45983	MAPK8	S428	G424S	424	Missense	distal	-4	no	2.205	3.093	EPSD	TCGA;ICGC;COSMIC	2.638	Gain
CMGC_MAPK_JNK_MAPK8_ST	P35568	IRS1	P45983	MAPK8	S434	S428L	428	Missense	distal	-6	no	6.144	6.325	EPSD	TCGA;ICGC;COSMIC	2.638	Up-regulation
CMGC_MAPK_JNK_MAPK8_ST	P35568	IRS1	P45983	MAPK8	S434	F438V	438	Missense	distal	4	no	6.144	6.084	EPSD	TCGA;ICGC;COSMIC	2.638	Down-regulation
CMGC_MAPK_JNK_MAPK8_ST	P35568	IRS1	P45983	MAPK8	T446	V445I	445	Missense	proximal	-1	no	6.626	6.648	EPSD	TCGA;ICGC;COSMIC	2.638	Up-regulation
CMGC_MAPK_JNK_MAPK8_ST	P35568	IRS1	P45983	MAPK8	T446	R443H	443	Missense	distal	-3	no	6.626	6.663	EPSD	TCGA;ICGC	2.638	Up-regulation
CMGC_MAPK_JNK_MAPK8_ST	P35568	IRS1	P45983	MAPK8	T495	T498I	498	Missense	distal	3	no	8.034	8.130	EPSD	TCGA;ICGC;COSMIC	2.638	Up-regulation
CMGC_MAPK_JNK_MAPK8_ST	P35568	IRS1	P45983	MAPK8	T495	G489C	489	Missense	distal	-6	no	8.034	8.013	EPSD	TCGA;ICGC;COSMIC	2.638	Down-regulation
CMGC_MAPK_JNK_MAPK8_ST	P35568	IRS1	P45983	MAPK8	T495	G488V	488	Missense	distal	-7	no	8.034	8.040	EPSD	TCGA;ICGC;COSMIC	2.638	Up-regulation
CMGC_MAPK_JNK_MAPK8_ST	P35568	IRS1	P45983	MAPK8	S503	T498I	498	Missense	distal	-5	no	7.527	7.731	EPSD	TCGA;ICGC;COSMIC	2.638	Up-regulation
CMGC_MAPK_JNK_MAPK8_ST	P35568	IRS1	P45983	MAPK8	S503	P504A	504	Missense	proximal	1	no	7.527	1.179	EPSD	TCGA;ICGC;COSMIC	2.638	Loss
CMGC_MAPK_JNK_MAPK8_ST	P35568	IRS1	P45983	MAPK8	S547	S544L	544	Missense	distal	-3	no	2.753	2.412	EPSD	TCGA;ICGC;COSMIC	2.638	Loss
CMGC_MAPK_JNK_MAPK8_ST	P35568	IRS1	P45983	MAPK8	S547	E553D	553	Missense	distal	6	no	2.753	2.718	EPSD	TCGA;ICGC;COSMIC	2.638	Down-regulation
CMGC_MAPK_JNK_MAPK8_ST	P35568	IRS1	P45983	MAPK8	S616	G611C	611	Missense	distal	-5	no	7.615	7.544	EPSD	TCGA;ICGC;COSMIC	2.638	Down-regulation
CMGC_MAPK_JNK_MAPK8_ST	P35568	IRS1	P45983	MAPK8	S666	S672C	672	Missense	distal	6	no	8.196	8.147	EPSD	TCGA;ICGC;COSMIC	2.638	Down-regulation
CMGC_MAPK_JNK_MAPK8_ST	P35568	IRS1	P45983	MAPK8	S672	I675V	675	Missense	distal	3	no	9.197	9.319	EPSD	TCGA;ICGC;COSMIC	2.638	Up-regulation
CMGC_MAPK_JNK_MAPK8_ST	P35568	IRS1	P45983	MAPK8	S672	G676E	676	Missense	distal	4	no	9.197	9.490	EPSD	TCGA	2.638	Up-regulation
CMGC_MAPK_JNK_MAPK8_ST	P35568	IRS1	P45983	MAPK8	S672	S672C	672	Missense	central	0	yes	9.197	0.000	EPSD	TCGA;ICGC;COSMIC	2.638	Loss
CMGC_MAPK_JNK_MAPK8_ST	P35568	IRS1	P45983	MAPK8	S736	M733I	733	Missense	distal	-3	no	6.755	6.921	EPSD	TCGA;ICGC;COSMIC	2.638	Up-regulation
CMGC_MAPK_JNK_MAPK8_ST	P35568	IRS1	P45983	MAPK8	S736	N742D	742	Missense	distal	6	no	6.755	6.786	EPSD	TCGA;ICGC;COSMIC	2.638	Up-regulation
CMGC_MAPK_JNK_MAPK8_ST	P35568	IRS1	P45983	MAPK8	S736	D731E	731	Missense	distal	-5	no	6.755	6.512	EPSD	TCGA;ICGC;COSMIC	2.638	Down-regulation
CMGC_MAPK_JNK_MAPK8_ST	P35568	IRS1	P45983	MAPK8	S745	N742D	742	Missense	distal	-3	no	8.391	8.556	EPSD	TCGA;ICGC;COSMIC	2.638	Up-regulation
CMGC_MAPK_JNK_MAPK8_ST	P35568	IRS1	P45983	MAPK8	S892	P890S	890	Missense	proximal	-2	no	9.443	9.337	EPSD	TCGA;ICGC;COSMIC	2.638	Down-regulation
CMGC_MAPK_JNK_MAPK8_ST	P35568	IRS1	P45983	MAPK8	S985	R986W	986	Missense	proximal	1	no	1.378	2.841	EPSD	TCGA;ICGC;COSMIC;GDSC;CCLE	2.638	Gain
CMGC_MAPK_JNK_MAPK8_ST	P35568	IRS1	P45983	MAPK8	S1005	S1005L	1005	Missense	central	0	yes	7.156	0.000	EPSD	TCGA;ICGC	2.638	Loss
CMGC_MAPK_JNK_MAPK8_ST	P35568	IRS1	P45983	MAPK8	S1041	P1047S	1047	Missense	distal	6	no	2.655	2.680	EPSD	TCGA;ICGC;COSMIC	2.638	Up-regulation
CMGC_MAPK_JNK_MAPK8_ST	P35568	IRS1	P45983	MAPK8	S1043	P1047S	1047	Missense	distal	4	no	8.796	8.821	EPSD	TCGA;ICGC;COSMIC	2.638	Up-regulation
CMGC_MAPK_JNK_MAPK8_ST	P35568	IRS1	P45983	MAPK8	S1078	R1081H	1081	Missense	distal	3	no	5.863	5.845	EPSD	TCGA;ICGC;COSMIC	2.638	Down-regulation
CMGC_MAPK_JNK_MAPK8_ST	P35568	IRS1	P45983	MAPK8	T1107	S1109C	1109	Missense	proximal	2	no	7.378	7.185	EPSD	TCGA;ICGC;COSMIC	2.638	Down-regulation
CMGC_MAPK_JNK_MAPK8_ST	P35568	IRS1	P45983	MAPK8	S1109	S1109C	1109	Missense	central	0	yes	2.694	0.000	EPSD	TCGA;ICGC;COSMIC	2.638	Loss
CMGC_MAPK_JNK_MAPK8_ST	P35568	IRS1	P45983	MAPK8	S1231	S1233G	1233	Missense	proximal	2	no	3.402	3.200	EPSD	TCGA;ICGC;COSMIC	2.638	Down-regulation
CMGC_MAPK_JNK_MAPK8_ST	Q15750	TAB1	P45983	MAPK8	S16	D20Y	20	Missense	distal	4	no	2.729	2.406	EPSD	TCGA	2.638	Loss
CMGC_MAPK_JNK_MAPK8_ST	Q15750	TAB1	P45983	MAPK8	S16	W17C	17	Missense	proximal	1	no	2.729	0.824	EPSD	TCGA;ICGC;COSMIC	2.638	Loss
CMGC_MAPK_JNK_MAPK8_ST	Q15750	TAB1	P45983	MAPK8	S31	V29A	29	Missense	proximal	-2	no	3.235	3.426	EPSD	TCGA;ICGC;COSMIC	2.638	Up-regulation
CMGC_MAPK_JNK_MAPK8_ST	Q15750	TAB1	P45983	MAPK8	S339	R336C	336	Missense	distal	-3	no	3.196	3.246	EPSD	TCGA;ICGC;COSMIC	2.638	Up-regulation
CMGC_MAPK_JNK_MAPK8_ST	Q15750	TAB1	P45983	MAPK8	S339	R336H	336	Missense	distal	-3	no	3.196	3.233	EPSD	TCGA;ICGC;COSMIC	2.638	Up-regulation
CMGC_MAPK_JNK_MAPK8_ST	Q15750	TAB1	P45983	MAPK8	S339	R333P	333	Missense	distal	-6	no	3.196	3.130	EPSD	TCGA;ICGC;COSMIC	2.638	Down-regulation
CMGC_MAPK_JNK_MAPK8_ST	Q15750	TAB1	P45983	MAPK8	S339	D340N	340	Missense	proximal	1	no	3.196	1.138	EPSD	TCGA;ICGC;COSMIC	2.638	Loss
CMGC_MAPK_JNK_MAPK8_ST	Q15750	TAB1	P45983	MAPK8	T431	E429K	429	Missense	proximal	-2	no	6.638	6.635	EPSD	TCGA;ICGC;COSMIC	2.638	Down-regulation
CMGC_MAPK_JNK_MAPK8_ST	Q15750	TAB1	P45983	MAPK8	T431	A430T	430	Missense	proximal	-1	no	6.638	6.637	EPSD	TCGA;ICGC;COSMIC	2.638	Down-regulation
CMGC_MAPK_JNK_MAPK8_ST	Q15750	TAB1	P45983	MAPK8	T431	T433I	433	Missense	proximal	2	no	6.638	6.512	EPSD	TCGA;ICGC;COSMIC	2.638	Down-regulation
CMGC_MAPK_JNK_MAPK8_ST	Q15750	TAB1	P45983	MAPK8	S438	T433I	433	Missense	distal	-5	no	7.509	7.714	PhosphoSitePlus	TCGA;ICGC;COSMIC	2.638	Up-regulation
CMGC_MAPK_JNK_MAPK8_ST	P40763	STAT3	P45983	MAPK8	T236	A241D	241	Missense	distal	5	no	3.826	3.865	EPSD	TCGA;COSMIC	2.638	Up-regulation
CMGC_MAPK_JNK_MAPK8_ST	P40763	STAT3	P45983	MAPK8	T236	Q232H	232	Missense	distal	-4	no	3.826	3.364	EPSD	TCGA;COSMIC	2.638	Down-regulation
CMGC_MAPK_JNK_MAPK8_ST	P40763	STAT3	P45983	MAPK8	T714	S719N	719	Missense	distal	5	no	8.025	8.094	EPSD	TCGA;ICGC	2.638	Up-regulation
CMGC_MAPK_JNK_MAPK8_ST	P40763	STAT3	P45983	MAPK8	T721	P725L	725	Missense	distal	4	no	2.709	2.302	EPSD	TCGA;ICGC;COSMIC	2.638	Loss
CMGC_MAPK_JNK_MAPK8_ST	P40763	STAT3	P45983	MAPK8	T721	S719N	719	Missense	proximal	-2	no	2.709	2.591	EPSD	TCGA;ICGC	2.638	Loss
CMGC_MAPK_JNK_MAPK8_ST	P40763	STAT3	P45983	MAPK8	S727	R729H	729	Missense	proximal	2	no	7.051	7.109	PhosphoSitePlus	TCGA;ICGC;COSMIC;GDSC;CCLE	2.638	Up-regulation
CMGC_MAPK_JNK_MAPK8_ST	P40763	STAT3	P45983	MAPK8	S727	P725L	725	Missense	proximal	-2	no	7.051	6.858	PhosphoSitePlus	TCGA;ICGC;COSMIC	2.638	Down-regulation
CMGC_MAPK_JNK_MAPK8_ST	P61978	HNRNPK	P45983	MAPK8	S116	P117L	117	Missense	proximal	1	no	7.091	-0.481	EPSD	TCGA;ICGC	2.638	Loss
CMGC_MAPK_JNK_MAPK8_ST	P61978	HNRNPK	P45983	MAPK8	S216	R221H	221	Missense	distal	5	no	7.728	7.706	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	2.638	Down-regulation
CMGC_MAPK_JNK_MAPK8_ST	P61978	HNRNPK	P45983	MAPK8	S284	M283V	283	Missense	proximal	-1	no	7.902	7.894	EPSD	TCGA;ICGC;COSMIC	2.638	Down-regulation
CMGC_MAPK_JNK_MAPK8_ST	P61978	HNRNPK	P45983	MAPK8	T351	S355L	355	Missense	distal	4	no	2.668	2.236	EPSD	TCGA;ICGC;COSMIC	2.638	Loss
CMGC_MAPK_JNK_MAPK8_ST	P61978	HNRNPK	P45983	MAPK8	T351	E356D	356	Missense	distal	5	no	2.668	2.725	EPSD	TCGA;ICGC;COSMIC	2.638	Up-regulation
CMGC_MAPK_JNK_MAPK8_ST	P61978	HNRNPK	P45983	MAPK8	T351	E356A	356	Missense	distal	5	no	2.668	2.687	EPSD	TCGA;ICGC;COSMIC	2.638	Up-regulation
CMGC_MAPK_JNK_MAPK8_ST	P61978	HNRNPK	P45983	MAPK8	S353	S355L	355	Missense	proximal	2	no	7.439	7.177	PhosphoSitePlus;EPSD	TCGA;ICGC;COSMIC	2.638	Down-regulation
CMGC_MAPK_JNK_MAPK8_ST	P61978	HNRNPK	P45983	MAPK8	S353	E356D	356	Missense	distal	3	no	7.439	7.547	PhosphoSitePlus;EPSD	TCGA;ICGC;COSMIC	2.638	Up-regulation
CMGC_MAPK_JNK_MAPK8_ST	P61978	HNRNPK	P45983	MAPK8	S353	E356A	356	Missense	distal	3	no	7.439	7.445	PhosphoSitePlus;EPSD	TCGA;ICGC;COSMIC	2.638	Up-regulation
CMGC_MAPK_JNK_MAPK8_ST	P61978	HNRNPK	P45983	MAPK8	S420	R414C	414	Missense	distal	-6	no	3.142	3.117	EPSD	TCGA;ICGC;COSMIC;CCLE	2.638	Down-regulation
CMGC_MAPK_JNK_MAPK8_ST	P61978	HNRNPK	P45983	MAPK8	S420	E425D	425	Missense	distal	5	no	3.142	3.200	EPSD	TCGA;ICGC	2.638	Up-regulation
CMGC_MAPK_JNK_MAPK8_ST	P98177	FOXO4	P45983	MAPK8	S111	A113V	113	Missense	proximal	2	no	2.676	2.359	EPSD	TCGA;COSMIC	2.638	Loss
CMGC_MAPK_JNK_MAPK8_ST	P98177	FOXO4	P45983	MAPK8	S111	Q112H	112	Missense	proximal	1	no	2.676	1.870	EPSD	TCGA;COSMIC	2.638	Loss
CMGC_MAPK_JNK_MAPK8_ST	P98177	FOXO4	P45983	MAPK8	T227	E224K	224	Missense	distal	-3	no	8.527	8.554	EPSD;PhosphoSitePlus	TCGA;COSMIC	2.638	Up-regulation
CMGC_MAPK_JNK_MAPK8_ST	P98177	FOXO4	P45983	MAPK8	T227	G233D	233	Missense	distal	6	no	8.527	8.550	EPSD;PhosphoSitePlus	TCGA;COSMIC	2.638	Up-regulation
CMGC_MAPK_JNK_MAPK8_ST	P98177	FOXO4	P45983	MAPK8	T227	P231T	231	Missense	distal	4	no	8.527	8.504	EPSD;PhosphoSitePlus	TCGA;COSMIC	2.638	Down-regulation
CMGC_MAPK_JNK_MAPK8_ST	P98177	FOXO4	P45983	MAPK8	S230	E224K	224	Missense	distal	-6	no	7.842	7.837	EPSD;PhosphoSitePlus	TCGA;COSMIC	2.638	Down-regulation
CMGC_MAPK_JNK_MAPK8_ST	P98177	FOXO4	P45983	MAPK8	S230	G233D	233	Missense	distal	3	no	7.842	7.772	EPSD;PhosphoSitePlus	TCGA;COSMIC	2.638	Down-regulation
CMGC_MAPK_JNK_MAPK8_ST	P98177	FOXO4	P45983	MAPK8	S230	P231T	231	Missense	proximal	1	no	7.842	0.855	EPSD;PhosphoSitePlus	TCGA;COSMIC	2.638	Loss
CMGC_MAPK_JNK_MAPK8_ST	P98177	FOXO4	P45983	MAPK8	S241	R247H	247	Missense	distal	6	no	8.461	8.473	EPSD	TCGA;COSMIC;CCLE	2.638	Up-regulation
CMGC_MAPK_JNK_MAPK8_ST	P98177	FOXO4	P45983	MAPK8	S241	N246D	246	Missense	distal	5	no	8.461	8.439	EPSD	TCGA;COSMIC	2.638	Down-regulation
CMGC_MAPK_JNK_MAPK8_ST	P98177	FOXO4	P45983	MAPK8	S241	R247C	247	Missense	distal	6	no	8.461	8.473	EPSD	TCGA;COSMIC	2.638	Up-regulation
CMGC_MAPK_JNK_MAPK8_ST	P98177	FOXO4	P45983	MAPK8	T451	A448D	448	Missense	distal	-3	no	7.800	7.577	EPSD;PhosphoSitePlus	TCGA;COSMIC	2.638	Down-regulation
CMGC_MAPK_JNK_MAPK8_ST	P98177	FOXO4	P45983	MAPK8	T451	P446L	446	Missense	distal	-5	no	7.800	8.160	EPSD;PhosphoSitePlus	TCGA;COSMIC	2.638	Up-regulation
CMGC_MAPK_JNK_MAPK8_ST	P98177	FOXO4	P45983	MAPK8	T455	A448D	448	Missense	distal	-7	no	8.305	8.313	PhosphoSitePlus;EPSD	TCGA;COSMIC	2.638	Up-regulation
CMGC_MAPK_JNK_MAPK8_ST	P31946	YWHAB	P45983	MAPK8	S60	R62C	62	Missense	proximal	2	no	3.202	3.250	EPSD	TCGA;ICGC;COSMIC	2.638	Up-regulation
CMGC_MAPK_JNK_MAPK8_ST	P31946	YWHAB	P45983	MAPK8	S60	R58L	58	Missense	proximal	-2	no	3.202	3.192	EPSD	TCGA;ICGC;COSMIC	2.638	Down-regulation
CMGC_MAPK_JNK_MAPK8_ST	P31946	YWHAB	P45983	MAPK8	S60	R58H	58	Missense	proximal	-2	no	3.202	3.201	EPSD	TCGA;ICGC	2.638	Down-regulation
CMGC_MAPK_JNK_MAPK8_ST	Q9NZ72	STMN3	P45983	MAPK8	S6	K9N	9	Missense	distal	3	no	2.777	3.021	EPSD	TCGA	2.638	Up-regulation
CMGC_MAPK_JNK_MAPK8_ST	Q9NZ72	STMN3	P45983	MAPK8	S60	F54L	54	Missense	distal	-6	no	8.468	8.467	PhosphoSitePlus	TCGA;COSMIC	2.638	Down-regulation
CMGC_MAPK_JNK_MAPK8_ST	Q9NZ72	STMN3	P45983	MAPK8	S60	S65F	65	Missense	distal	5	no	8.468	8.544	PhosphoSitePlus	TCGA	2.638	Up-regulation
CMGC_MAPK_JNK_MAPK8_ST	Q9NZ72	STMN3	P45983	MAPK8	S65	S65F	65	Missense	central	0	yes	8.449	0.000	EPSD	TCGA	2.638	Loss
CMGC_MAPK_JNK_MAPK8_ST	Q9NZ72	STMN3	P45983	MAPK8	S68	P74S	74	Missense	distal	6	no	7.193	7.217	EPSD	TCGA;COSMIC	2.638	Up-regulation
CMGC_MAPK_JNK_MAPK8_ST	Q9NZ72	STMN3	P45983	MAPK8	S68	S65F	65	Missense	distal	-3	no	7.193	6.819	EPSD	TCGA	2.638	Down-regulation
CMGC_MAPK_JNK_MAPK8_ST	Q9NZ72	STMN3	P45983	MAPK8	S73	P74S	74	Missense	proximal	1	no	7.517	-0.212	EPSD	TCGA;COSMIC	2.638	Loss
CMGC_MAPK_JNK_MAPK8_ST	Q14653	IRF3	P45983	MAPK8	S123	D116Y	116	Missense	distal	-7	no	7.954	7.966	EPSD	TCGA;ICGC;COSMIC	2.638	Up-regulation
CMGC_MAPK_JNK_MAPK8_ST	Q14653	IRF3	P45983	MAPK8	S123	G129E	129	Missense	distal	6	no	7.954	8.012	EPSD	TCGA;COSMIC	2.638	Up-regulation
CMGC_MAPK_JNK_MAPK8_ST	Q14653	IRF3	P45983	MAPK8	S173	P170S	170	Missense	distal	-3	no	8.448	8.611	PhosphoSitePlus	TCGA;COSMIC;CCLE	2.638	Up-regulation
CMGC_MAPK_JNK_MAPK8_ST	P04150	NR3C1	P45983	MAPK8	T8	P9H	9	Missense	proximal	1	no	8.138	0.222	EPSD	TCGA;COSMIC	2.638	Loss
CMGC_MAPK_JNK_MAPK8_ST	P04150	NR3C1	P45983	MAPK8	S45	S42Y	42	Missense	distal	-3	no	8.217	7.734	EPSD	TCGA;ICGC;COSMIC	2.638	Down-regulation
CMGC_MAPK_JNK_MAPK8_ST	P04150	NR3C1	P45983	MAPK8	T145	K140N	140	Missense	distal	-5	no	2.136	2.663	EPSD	TCGA;ICGC;COSMIC	2.638	Gain
CMGC_MAPK_JNK_MAPK8_ST	P04150	NR3C1	P45983	MAPK8	S211	P212H	212	Missense	proximal	1	no	7.111	-0.804	EPSD	TCGA;ICGC;COSMIC	2.638	Loss
CMGC_MAPK_JNK_MAPK8_ST	P04150	NR3C1	P45983	MAPK8	S226	N222T	222	Missense	distal	-4	no	7.390	8.049	PhosphoSitePlus	TCGA;ICGC;COSMIC	2.638	Up-regulation
CMGC_MAPK_JNK_MAPK8_ST	P04150	NR3C1	P45983	MAPK8	S226	A229V	229	Missense	distal	3	no	7.390	7.617	PhosphoSitePlus	TCGA;ICGC;COSMIC	2.638	Up-regulation
CMGC_MAPK_JNK_MAPK8_ST	P04150	NR3C1	P45983	MAPK8	S226	G230R	230	Missense	distal	4	no	7.390	7.368	PhosphoSitePlus	TCGA;ICGC	2.638	Down-regulation
CMGC_MAPK_JNK_MAPK8_ST	P04150	NR3C1	P45983	MAPK8	S226	I219L	219	Missense	distal	-7	no	7.390	7.398	PhosphoSitePlus	TCGA;ICGC;COSMIC	2.638	Up-regulation
CMGC_MAPK_JNK_MAPK8_ST	P04150	NR3C1	P45983	MAPK8	T288	P289S	289	Missense	proximal	1	no	7.401	-0.328	EPSD	TCGA;ICGC;COSMIC	2.638	Loss
CMGC_MAPK_JNK_MAPK8_ST	P04150	NR3C1	P45983	MAPK8	S395	S395I	395	Missense	central	0	yes	7.684	0.000	EPSD	TCGA;ICGC	2.638	Loss
CMGC_MAPK_JNK_MAPK8_ST	P04150	NR3C1	P45983	MAPK8	S404	S404Y	404	Missense	central	0	yes	8.117	0.000	EPSD	TCGA;ICGC	2.638	Loss
CMGC_MAPK_JNK_MAPK8_ST	P04150	NR3C1	P45983	MAPK8	T411	S404Y	404	Missense	distal	-7	no	2.730	2.751	EPSD	TCGA;ICGC	2.638	Up-regulation
CMGC_MAPK_JNK_MAPK8_ST	P04150	NR3C1	P45983	MAPK8	T411	P416Q	416	Missense	distal	5	no	2.730	2.667	EPSD	TCGA;ICGC;COSMIC	2.638	Down-regulation
CMGC_MAPK_JNK_MAPK8_ST	Q9NPI6	DCP1A	P45983	MAPK8	S62	R58Q	58	Missense	distal	-4	no	7.497	8.017	EPSD	TCGA;ICGC;COSMIC	2.638	Up-regulation
CMGC_MAPK_JNK_MAPK8_ST	Q9NPI6	DCP1A	P45983	MAPK8	S142	R138W	138	Missense	distal	-4	no	7.254	7.010	EPSD	TCGA;ICGC;COSMIC	2.638	Down-regulation
CMGC_MAPK_JNK_MAPK8_ST	Q9NPI6	DCP1A	P45983	MAPK8	S194	T195I	195	Missense	proximal	1	no	1.646	2.759	EPSD	TCGA;ICGC;COSMIC;GDSC;CCLE	2.638	Gain
CMGC_MAPK_JNK_MAPK8_ST	Q9NPI6	DCP1A	P45983	MAPK8	T348	R350T	350	Missense	proximal	2	no	7.103	7.348	EPSD	TCGA;COSMIC	2.638	Up-regulation
CMGC_MAPK_JNK_MAPK8_ST	Q9NPI6	DCP1A	P45983	MAPK8	S353	R350T	350	Missense	distal	-3	no	7.247	7.534	EPSD	TCGA;COSMIC	2.638	Up-regulation
CMGC_MAPK_JNK_MAPK8_ST	Q9NPI6	DCP1A	P45983	MAPK8	S373	Q372H	372	Missense	proximal	-1	no	7.578	7.563	EPSD	TCGA;COSMIC	2.638	Down-regulation
CMGC_MAPK_JNK_MAPK8_ST	Q9NPI6	DCP1A	P45983	MAPK8	T401	H404R	404	Missense	distal	3	no	8.746	8.765	EPSD	TCGA	2.638	Up-regulation
CMGC_MAPK_JNK_MAPK8_ST	Q9NPI6	DCP1A	P45983	MAPK8	S422	P423L	423	Missense	proximal	1	no	8.028	0.456	EPSD	TCGA;ICGC;COSMIC	2.638	Loss
CMGC_MAPK_JNK_MAPK8_ST	Q9NPI6	DCP1A	P45983	MAPK8	T430	E432K	432	Missense	proximal	2	no	6.351	6.369	EPSD	TCGA;COSMIC	2.638	Up-regulation
CMGC_MAPK_JNK_MAPK8_ST	Q9NPI6	DCP1A	P45983	MAPK8	T430	P423L	423	Missense	distal	-7	no	6.351	6.362	EPSD	TCGA;ICGC;COSMIC	2.638	Up-regulation
CMGC_MAPK_JNK_MAPK8_ST	Q06481	APLP2	P45983	MAPK8	T736	H741R	741	Missense	distal	5	no	7.976	7.997	PhosphoSitePlus	TCGA;COSMIC	2.638	Up-regulation
CMGC_MAPK_JNK_MAPK8_ST	Q9H2B2	SYT4	P45983	MAPK8	S114	L118M	118	Missense	distal	4	no	8.459	8.481	EPSD	TCGA;COSMIC	2.638	Up-regulation
CMGC_MAPK_JNK_MAPK8_ST	Q9H2B2	SYT4	P45983	MAPK8	S114	G113S	113	Missense	proximal	-1	no	8.459	8.483	EPSD	TCGA;COSMIC	2.638	Up-regulation
CMGC_MAPK_JNK_MAPK8_ST	Q9H2B2	SYT4	P45983	MAPK8	S114	N120I	120	Missense	distal	6	no	8.459	8.490	EPSD	TCGA;COSMIC	2.638	Up-regulation
CMGC_MAPK_JNK_MAPK8_ST	Q9H2B2	SYT4	P45983	MAPK8	S114	L118Q	118	Missense	distal	4	no	8.459	8.759	EPSD	TCGA;COSMIC	2.638	Up-regulation
CMGC_MAPK_JNK_MAPK8_ST	Q9H2B2	SYT4	P45983	MAPK8	S114	P112S	112	Missense	proximal	-2	no	8.459	8.353	EPSD	TCGA;COSMIC	2.638	Down-regulation
CMGC_MAPK_JNK_MAPK8_ST	Q9H2B2	SYT4	P45983	MAPK8	S116	L118M	118	Missense	proximal	2	no	2.628	2.642	EPSD	TCGA;COSMIC	2.638	Gain
CMGC_MAPK_JNK_MAPK8_ST	Q9H2B2	SYT4	P45983	MAPK8	S116	G113S	113	Missense	distal	-3	no	2.628	2.909	EPSD	TCGA;COSMIC	2.638	Gain
CMGC_MAPK_JNK_MAPK8_ST	Q9H2B2	SYT4	P45983	MAPK8	S116	N120I	120	Missense	distal	4	no	2.628	2.887	EPSD	TCGA;COSMIC	2.638	Gain
CMGC_MAPK_JNK_MAPK8_ST	Q9H2B2	SYT4	P45983	MAPK8	S116	L118Q	118	Missense	proximal	2	no	2.628	2.823	EPSD	TCGA;COSMIC	2.638	Gain
CMGC_MAPK_JNK_MAPK8_ST	Q9H2B2	SYT4	P45983	MAPK8	S116	P112S	112	Missense	distal	-4	no	2.628	3.293	EPSD	TCGA;COSMIC	2.638	Gain
CMGC_MAPK_JNK_MAPK8_ST	Q9H2B2	SYT4	P45983	MAPK8	T122	T122N	122	Missense	central	0	yes	7.396	0.000	EPSD	TCGA;COSMIC	2.638	Loss
CMGC_MAPK_JNK_MAPK8_ST	Q9H2B2	SYT4	P45983	MAPK8	T122	L118M	118	Missense	distal	-4	no	7.396	7.471	EPSD	TCGA;COSMIC	2.638	Up-regulation
CMGC_MAPK_JNK_MAPK8_ST	Q9H2B2	SYT4	P45983	MAPK8	T122	N120I	120	Missense	proximal	-2	no	7.396	7.516	EPSD	TCGA;COSMIC	2.638	Up-regulation
CMGC_MAPK_JNK_MAPK8_ST	Q9H2B2	SYT4	P45983	MAPK8	T122	P123T	123	Missense	proximal	1	no	7.396	0.409	EPSD	TCGA;COSMIC	2.638	Loss
CMGC_MAPK_JNK_MAPK8_ST	Q9H2B2	SYT4	P45983	MAPK8	T122	L118Q	118	Missense	distal	-4	no	7.396	8.107	EPSD	TCGA;COSMIC	2.638	Up-regulation
CMGC_MAPK_JNK_MAPK8_ST	Q9H2B2	SYT4	P45983	MAPK8	T122	P123Q	123	Missense	proximal	1	no	7.396	0.287	EPSD	TCGA;COSMIC	2.638	Loss
CMGC_MAPK_JNK_MAPK8_ST	Q9H2B2	SYT4	P45983	MAPK8	T122	G129E	129	Missense	distal	7	no	7.396	7.331	EPSD	TCGA;COSMIC	2.638	Down-regulation
CMGC_MAPK_JNK_MAPK8_ST	Q9H2B2	SYT4	P45983	MAPK8	S135	G129E	129	Missense	distal	-6	no	9.420	9.262	PhosphoSitePlus	TCGA;COSMIC	2.638	Down-regulation
CMGC_MAPK_JNK_MAPK8_ST	Q9H2B2	SYT4	P45983	MAPK8	S135	S135F	135	Missense	central	0	yes	9.420	0.000	PhosphoSitePlus	TCGA;COSMIC	2.638	Loss
CMGC_MAPK_JNK_MAPK8_ST	Q9H2B2	SYT4	P45983	MAPK8	S135	S141F	141	Missense	distal	6	no	9.420	9.351	PhosphoSitePlus	TCGA	2.638	Down-regulation
CMGC_MAPK_JNK_MAPK8_ST	Q16621	NFE2	P45983	MAPK8	S2	P3L	3	Missense	proximal	1	no	7.248	-0.325	EPSD	TCGA;ICGC;COSMIC	2.638	Loss
CMGC_MAPK_JNK_MAPK8_ST	Q16621	NFE2	P45983	MAPK8	S2	Q7E	7	Missense	distal	5	no	7.248	7.217	EPSD	TCGA;ICGC;COSMIC	2.638	Down-regulation
CMGC_MAPK_JNK_MAPK8_ST	Q16621	NFE2	P45983	MAPK8	S107	L112P	112	Missense	distal	5	no	2.972	2.974	EPSD	TCGA;ICGC	2.638	Up-regulation
CMGC_MAPK_JNK_MAPK8_ST	Q16621	NFE2	P45983	MAPK8	S107	V106I	106	Missense	proximal	-1	no	2.972	2.994	EPSD	TCGA;ICGC	2.638	Up-regulation
CMGC_MAPK_JNK_MAPK8_ST	Q16621	NFE2	P45983	MAPK8	S107	L110P	110	Missense	distal	3	no	2.972	2.870	EPSD	TCGA;ICGC;COSMIC	2.638	Down-regulation
CMGC_MAPK_JNK_MAPK8_ST	Q16621	NFE2	P45983	MAPK8	S157	L158F	158	Missense	proximal	1	no	4.371	3.771	PhosphoSitePlus	TCGA;ICGC;COSMIC	2.638	Down-regulation
CMGC_MAPK_JNK_MAPK8_ST	Q16621	NFE2	P45983	MAPK8	S157	S157F	157	Missense	central	0	yes	4.371	0.000	PhosphoSitePlus	TCGA;ICGC;COSMIC	2.638	Loss
CMGC_MAPK_JNK_MAPK8_ST	Q16621	NFE2	P45983	MAPK8	S157	D154N	154	Missense	distal	-3	no	4.371	4.206	PhosphoSitePlus	TCGA;ICGC;COSMIC	2.638	Down-regulation
CMGC_MAPK_JNK_MAPK8_ST	Q16621	NFE2	P45983	MAPK8	S157	G162R	162	Missense	distal	5	no	4.371	4.375	PhosphoSitePlus	TCGA;ICGC;COSMIC;GDSC;CCLE	2.638	Up-regulation
CMGC_MAPK_JNK_MAPK8_ST	Q16621	NFE2	P45983	MAPK8	S157	E161K	161	Missense	distal	4	no	4.371	4.452	PhosphoSitePlus	TCGA;ICGC;COSMIC	2.638	Up-regulation
CMGC_MAPK_JNK_MAPK8_ST	Q16621	NFE2	P45983	MAPK8	S346	L352P	352	Missense	distal	6	no	8.549	8.596	EPSD	TCGA;ICGC;COSMIC	2.638	Up-regulation
CMGC_MAPK_JNK_MAPK8_ST	Q16621	NFE2	P45983	MAPK8	S346	E348K	348	Missense	proximal	2	no	8.549	8.567	EPSD	TCGA;ICGC;COSMIC	2.638	Up-regulation
CMGC_MAPK_JNK_MAPK8_ST	Q16621	NFE2	P45983	MAPK8	S346	P347L	347	Missense	proximal	1	no	8.549	0.977	EPSD	TCGA;ICGC;COSMIC	2.638	Loss
CAMK_CAMKL_MARK_MARK3_ST	Q06413	MEF2C	P27448	MARK3	S59	D63G	63	Missense	distal	4	no	272.923	272.976	EPSD	TCGA;ICGC;COSMIC	255.132	Up-regulation
CAMK_CAMKL_MARK_MARK3_ST	Q06413	MEF2C	P27448	MARK3	S98	A103V	103	Missense	distal	5	no	283.062	264.752	EPSD	TCGA;ICGC	255.132	Down-regulation
CAMK_CAMKL_MARK_MARK3_ST	Q06413	MEF2C	P27448	MARK3	S98	C96F	96	Missense	proximal	-2	no	283.062	281.929	EPSD	TCGA;ICGC;COSMIC	255.132	Down-regulation
CAMK_CAMKL_MARK_MARK3_ST	Q06413	MEF2C	P27448	MARK3	S387	S387I	387	Missense	central	0	yes	325.011	0.000	EPSD	TCGA;COSMIC	255.132	Loss
CAMK_CAMKL_MARK_MARK3_ST	Q06413	MEF2C	P27448	MARK3	S392	S387I	387	Missense	distal	-5	no	245.990	258.723	EPSD	TCGA;COSMIC	255.132	Gain
CAMK_CAMKL_MARK_MARK3_ST	Q99689	FEZ1	P27448	MARK3	S58	E52K	52	Missense	distal	-6	no	543.846	542.573	PhosphoSitePlus	TCGA;ICGC;COSMIC	255.132	Down-regulation
CAMK_CAMKL_MARK_MARK3_ST	Q99689	FEZ1	P27448	MARK3	S58	V63I	63	Missense	distal	5	no	543.846	545.689	PhosphoSitePlus	TCGA;ICGC;COSMIC	255.132	Up-regulation
CAMK_CAMKL_MARK_MARK3_ST	Q99689	FEZ1	P27448	MARK3	S58	S55I	55	Missense	distal	-3	no	543.846	518.810	PhosphoSitePlus	TCGA;ICGC;COSMIC	255.132	Down-regulation
CAMK_CAMKL_MARK_MARK3_ST	Q99689	FEZ1	P27448	MARK3	S58	N64T	64	Missense	distal	6	no	543.846	539.993	PhosphoSitePlus	TCGA;ICGC;COSMIC	255.132	Down-regulation
CAMK_CAMKL_MARK_MARK3_ST	Q99689	FEZ1	P27448	MARK3	S58	L62I	62	Missense	distal	4	no	543.846	544.180	PhosphoSitePlus	TCGA;ICGC;COSMIC	255.132	Up-regulation
CAMK_CAMKL_MARK_MARK3_ST	Q99689	FEZ1	P27448	MARK3	T136	S134C	134	Missense	proximal	-2	no	257.380	263.811	EPSD	TCGA;ICGC;COSMIC	255.132	Up-regulation
CAMK_CAMKL_MARK_MARK3_ST	Q99689	FEZ1	P27448	MARK3	T136	S134Y	134	Missense	proximal	-2	no	257.380	257.256	EPSD	TCGA;ICGC;COSMIC	255.132	Down-regulation
CAMK_CAMKL_MARK_MARK3_ST	Q92974	ARHGEF2	P27448	MARK3	S46	S48T	48	Missense	proximal	2	no	308.387	349.416	EPSD	TCGA;COSMIC	255.132	Up-regulation
CAMK_CAMKL_MARK_MARK3_ST	Q92974	ARHGEF2	P27448	MARK3	S121	P120L	120	Missense	proximal	-1	no	291.536	291.870	EPSD	TCGA;COSMIC	255.132	Up-regulation
CAMK_CAMKL_MARK_MARK3_ST	Q92974	ARHGEF2	P27448	MARK3	S121	P126S	126	Missense	distal	5	no	291.536	321.851	EPSD	TCGA;COSMIC	255.132	Up-regulation
CAMK_CAMKL_MARK_MARK3_ST	Q92974	ARHGEF2	P27448	MARK3	S121	R117Q	117	Missense	distal	-4	no	291.536	285.993	EPSD	TCGA;COSMIC	255.132	Down-regulation
CAMK_CAMKL_MARK_MARK3_ST	Q92974	ARHGEF2	P27448	MARK3	S142	R139H	139	Missense	distal	-3	no	286.251	237.971	EPSD	TCGA;ICGC;COSMIC	255.132	Loss
CAMK_CAMKL_MARK_MARK3_ST	Q92974	ARHGEF2	P27448	MARK3	S143	R139H	139	Missense	distal	-4	no	373.920	353.388	EPSD	TCGA;ICGC;COSMIC	255.132	Down-regulation
CAMK_CAMKL_MARK_MARK3_ST	Q92974	ARHGEF2	P27448	MARK3	S172	R168C	168	Missense	distal	-4	no	335.738	328.942	EPSD	TCGA;ICGC;COSMIC	255.132	Down-regulation
CAMK_CAMKL_MARK_MARK3_ST	Q92974	ARHGEF2	P27448	MARK3	S172	S174F	174	Missense	proximal	2	no	335.738	348.224	EPSD	TCGA;COSMIC;CCLE	255.132	Up-regulation
CAMK_CAMKL_MARK_MARK3_ST	Q92974	ARHGEF2	P27448	MARK3	S177	R183Q	183	Missense	distal	6	no	297.025	280.601	EPSD	TCGA;COSMIC	255.132	Down-regulation
CAMK_CAMKL_MARK_MARK3_ST	Q92974	ARHGEF2	P27448	MARK3	S177	S174F	174	Missense	distal	-3	no	297.025	283.018	EPSD	TCGA;COSMIC;CCLE	255.132	Down-regulation
CAMK_CAMKL_MARK_MARK3_ST	Q92974	ARHGEF2	P27448	MARK3	S177	T184I	184	Missense	distal	7	no	297.025	298.184	EPSD	TCGA;COSMIC	255.132	Up-regulation
CAMK_CAMKL_MARK_MARK3_ST	Q92974	ARHGEF2	P27448	MARK3	S186	R183Q	183	Missense	distal	-3	no	344.357	316.408	EPSD	TCGA;COSMIC	255.132	Down-regulation
CAMK_CAMKL_MARK_MARK3_ST	Q92974	ARHGEF2	P27448	MARK3	S186	T184I	184	Missense	proximal	-2	no	344.357	347.506	EPSD	TCGA;COSMIC	255.132	Up-regulation
CAMK_CAMKL_MARK_MARK3_ST	Q92974	ARHGEF2	P27448	MARK3	T679	V674M	674	Missense	distal	-5	no	167.489	257.108	EPSD	TCGA	255.132	Gain
CAMK_CAMKL_MARK_MARK3_ST	Q92974	ARHGEF2	P27448	MARK3	S696	P697L	697	Missense	proximal	1	no	263.875	263.869	EPSD	TCGA;COSMIC	255.132	Down-regulation
CAMK_CAMKL_MARK_MARK3_ST	Q92974	ARHGEF2	P27448	MARK3	S696	P697A	697	Missense	proximal	1	no	263.875	263.880	EPSD	TCGA;COSMIC	255.132	Up-regulation
CAMK_CAMKL_MARK_MARK3_ST	Q92974	ARHGEF2	P27448	MARK3	S696	T695M	695	Missense	proximal	-1	no	263.875	264.201	EPSD	TCGA;COSMIC	255.132	Up-regulation
CAMK_CAMKL_MARK_MARK3_ST	Q92974	ARHGEF2	P27448	MARK3	T700	T695M	695	Missense	distal	-5	no	211.664	259.261	EPSD	TCGA;COSMIC	255.132	Gain
CAMK_CAMKL_MARK_MARK3_ST	Q92974	ARHGEF2	P27448	MARK3	S711	N709D	709	Missense	proximal	-2	no	271.732	270.623	EPSD	TCGA;COSMIC	255.132	Down-regulation
CAMK_CAMKL_MARK_MARK3_ST	Q92974	ARHGEF2	P27448	MARK3	S886	A889T	889	Missense	distal	3	no	293.478	294.568	EPSD	TCGA;COSMIC	255.132	Up-regulation
CAMK_CAMKL_MARK_MARK3_ST	Q92974	ARHGEF2	P27448	MARK3	S886	D891N	891	Missense	distal	5	no	293.478	333.709	EPSD	TCGA;COSMIC	255.132	Up-regulation
CAMK_CAMKL_MARK_MARK3_ST	Q92974	ARHGEF2	P27448	MARK3	S886	R885H	885	Missense	proximal	-1	no	293.478	294.278	EPSD	TCGA;COSMIC	255.132	Up-regulation
CAMK_CAMKL_MARK_MARK3_ST	Q92974	ARHGEF2	P27448	MARK3	S886	R883W	883	Missense	distal	-3	no	293.478	253.734	EPSD	TCGA;COSMIC	255.132	Loss
CAMK_CAMKL_MARK_MARK3_ST	Q92974	ARHGEF2	P27448	MARK3	S903	S896R	896	Missense	distal	-7	no	432.035	434.410	EPSD	TCGA;COSMIC	255.132	Up-regulation
CAMK_CAMKL_MARK_MARK3_ST	Q92974	ARHGEF2	P27448	MARK3	S947	S953R	953	Missense	distal	6	no	300.629	310.138	EPSD	TCGA;COSMIC	255.132	Up-regulation
CAMK_CAMKL_MARK_MARK3_ST	Q92974	ARHGEF2	P27448	MARK3	S947	R954H	954	Missense	distal	7	no	300.629	302.055	EPSD	TCGA;COSMIC	255.132	Up-regulation
CAMK_CAMKL_MARK_MARK3_ST	Q92974	ARHGEF2	P27448	MARK3	S947	R954C	954	Missense	distal	7	no	300.629	301.418	EPSD	TCGA;COSMIC	255.132	Up-regulation
CAMK_CAMKL_MARK_MARK3_ST	Q92974	ARHGEF2	P27448	MARK3	S956	S953R	953	Missense	distal	-3	no	270.831	290.581	EPSD	TCGA;COSMIC	255.132	Up-regulation
CAMK_CAMKL_MARK_MARK3_ST	Q92974	ARHGEF2	P27448	MARK3	S956	R954H	954	Missense	proximal	-2	no	270.831	255.030	EPSD	TCGA;COSMIC	255.132	Loss
CAMK_CAMKL_MARK_MARK3_ST	Q92974	ARHGEF2	P27448	MARK3	S956	R954C	954	Missense	proximal	-2	no	270.831	260.943	EPSD	TCGA;COSMIC	255.132	Down-regulation
CAMK_CAMKL_MARK_MARK3_ST	Q92974	ARHGEF2	P27448	MARK3	S956	S960N	960	Missense	distal	4	no	270.831	270.697	EPSD	TCGA;COSMIC	255.132	Down-regulation
CAMK_CAMKL_MARK_MARK3_ST	Q92974	ARHGEF2	P27448	MARK3	S960	R966T	966	Missense	distal	6	no	304.537	312.862	EPSD	TCGA;COSMIC	255.132	Up-regulation
CAMK_CAMKL_MARK_MARK3_ST	Q92974	ARHGEF2	P27448	MARK3	S960	S953R	953	Missense	distal	-7	no	304.537	306.911	EPSD	TCGA;COSMIC	255.132	Up-regulation
CAMK_CAMKL_MARK_MARK3_ST	Q92974	ARHGEF2	P27448	MARK3	S960	R954H	954	Missense	distal	-6	no	304.537	307.362	EPSD	TCGA;COSMIC	255.132	Up-regulation
CAMK_CAMKL_MARK_MARK3_ST	Q92974	ARHGEF2	P27448	MARK3	S960	R954C	954	Missense	distal	-6	no	304.537	306.160	EPSD	TCGA;COSMIC	255.132	Up-regulation
CAMK_CAMKL_MARK_MARK3_ST	Q92974	ARHGEF2	P27448	MARK3	S960	S960N	960	Missense	central	0	yes	304.537	0.000	EPSD	TCGA;COSMIC	255.132	Loss
CAMK_CAMKL_MARK_MARK3_ST	P41236	PPP1R2	P27448	MARK3	S7	S7L	7	Missense	central	0	yes	327.320	0.000	EPSD	TCGA;ICGC;COSMIC	255.132	Loss
CAMK_CAMKL_MARK_MARK3_ST	P41236	PPP1R2	P27448	MARK3	S28	P32S	32	Missense	distal	4	no	264.959	264.369	EPSD	TCGA;ICGC;COSMIC	255.132	Down-regulation
CAMK_CAMKL_MARK_MARK3_ST	P41236	PPP1R2	P27448	MARK3	S72	E70K	70	Missense	proximal	-2	no	555.959	573.684	PhosphoSitePlus	TCGA;ICGC;COSMIC	255.132	Up-regulation
CAMK_CAMKL_MARK_MARK3_ST	P41236	PPP1R2	P27448	MARK3	T73	E70K	70	Missense	distal	-3	no	309.398	343.656	EPSD	TCGA;ICGC;COSMIC	255.132	Up-regulation
CAMK_CAMKL_MARK_MARK3_ST	P30307	CDC25C	P27448	MARK3	T9	E4K	4	Missense	distal	-5	no	224.216	337.504	EPSD	TCGA;ICGC;COSMIC	255.132	Gain
CAMK_CAMKL_MARK_MARK3_ST	P30307	CDC25C	P27448	MARK3	S38	D36Y	36	Missense	proximal	-2	no	382.967	370.036	EPSD	TCGA;ICGC	255.132	Down-regulation
CAMK_CAMKL_MARK_MARK3_ST	P30307	CDC25C	P27448	MARK3	S191	E188D	188	Missense	distal	-3	no	248.497	258.849	EPSD	TCGA;ICGC	255.132	Gain
CAMK_CAMKL_MARK_MARK3_ST	P30307	CDC25C	P27448	MARK3	S191	E196K	196	Missense	distal	5	no	248.497	283.883	EPSD	TCGA;ICGC	255.132	Gain
CAMK_CAMKL_MARK_MARK3_ST	P30307	CDC25C	P27448	MARK3	S207	Q202E	202	Missense	distal	-5	no	242.365	268.076	EPSD	TCGA;ICGC;COSMIC	255.132	Gain
CAMK_CAMKL_MARK_MARK3_ST	P30307	CDC25C	P27448	MARK3	S214	P215Q	215	Missense	proximal	1	no	289.286	289.292	EPSD	TCGA;ICGC;COSMIC	255.132	Up-regulation
CAMK_CAMKL_MARK_MARK3_ST	P30307	CDC25C	P27448	MARK3	S214	R213H	213	Missense	proximal	-1	no	289.286	290.086	EPSD	TCGA;ICGC;COSMIC	255.132	Up-regulation
CAMK_CAMKL_MARK_MARK3_ST	P30307	CDC25C	P27448	MARK3	S214	R213C	213	Missense	proximal	-1	no	289.286	289.916	EPSD	TCGA;ICGC;COSMIC	255.132	Up-regulation
CAMK_CAMKL_MARK_MARK3_ST	P30307	CDC25C	P27448	MARK3	S214	S214F	214	Missense	central	0	yes	289.286	0.000	EPSD	TCGA;ICGC;COSMIC	255.132	Loss
CAMK_CAMKL_MARK_MARK3_ST	P30307	CDC25C	P27448	MARK3	S214	L221S	221	Missense	distal	7	no	289.286	290.186	EPSD	TCGA;ICGC;COSMIC	255.132	Up-regulation
CAMK_CAMKL_MARK_MARK3_ST	P30307	CDC25C	P27448	MARK3	S214	P218S	218	Missense	distal	4	no	289.286	288.696	EPSD	TCGA;ICGC	255.132	Down-regulation
CAMK_CAMKL_MARK_MARK3_ST	P30307	CDC25C	P27448	MARK3	S216	N222K	222	Missense	distal	6	no	655.162	666.716	PhosphoSitePlus	TCGA;ICGC;COSMIC	255.132	Up-regulation
CAMK_CAMKL_MARK_MARK3_ST	P30307	CDC25C	P27448	MARK3	S216	P215Q	215	Missense	proximal	-1	no	655.162	655.850	PhosphoSitePlus	TCGA;ICGC;COSMIC	255.132	Up-regulation
CAMK_CAMKL_MARK_MARK3_ST	P30307	CDC25C	P27448	MARK3	S216	R213H	213	Missense	distal	-3	no	655.162	606.883	PhosphoSitePlus	TCGA;ICGC;COSMIC	255.132	Down-regulation
CAMK_CAMKL_MARK_MARK3_ST	P30307	CDC25C	P27448	MARK3	S216	R213C	213	Missense	distal	-3	no	655.162	637.433	PhosphoSitePlus	TCGA;ICGC;COSMIC	255.132	Down-regulation
CAMK_CAMKL_MARK_MARK3_ST	P30307	CDC25C	P27448	MARK3	S216	S214F	214	Missense	proximal	-2	no	655.162	660.461	PhosphoSitePlus	TCGA;ICGC;COSMIC	255.132	Up-regulation
CAMK_CAMKL_MARK_MARK3_ST	P30307	CDC25C	P27448	MARK3	S216	L221S	221	Missense	distal	5	no	655.162	643.767	PhosphoSitePlus	TCGA;ICGC;COSMIC	255.132	Down-regulation
CAMK_CAMKL_MARK_MARK3_ST	P30307	CDC25C	P27448	MARK3	S216	P218S	218	Missense	proximal	2	no	655.162	585.151	PhosphoSitePlus	TCGA;ICGC	255.132	Down-regulation
CAMK_CAMKL_MARK_MARK3_ST	P30307	CDC25C	P27448	MARK3	S263	S263F	263	Missense	central	0	yes	260.518	0.000	EPSD	TCGA;ICGC;COSMIC	255.132	Loss
CAMK_CAMKL_MARK_MARK3_ST	P30307	CDC25C	P27448	MARK3	S277	G280E	280	Missense	distal	3	no	307.253	306.346	EPSD	TCGA;ICGC;COSMIC	255.132	Down-regulation
CAMK_CAMKL_MARK_MARK3_ST	P30307	CDC25C	P27448	MARK3	S277	S277C	277	Missense	central	0	yes	307.253	0.000	EPSD	TCGA;ICGC;COSMIC	255.132	Loss
CAMK_CAMKL_MARK_MARK3_ST	P30307	CDC25C	P27448	MARK3	S277	N278K	278	Missense	proximal	1	no	307.253	307.244	EPSD	TCGA;ICGC;COSMIC	255.132	Down-regulation
AGC_Akt_AKT2_ST	Q04656	ATP7A	P31751	AKT2	S262	E264V	264	Missense	proximal	2	no	26.611	27.336	EPSD	TCGA;ICGC;COSMIC	19.022	Up-regulation
AGC_Akt_AKT2_ST	Q04656	ATP7A	P31751	AKT2	S272	Y273C	273	Missense	proximal	1	no	23.452	24.062	EPSD	TCGA;ICGC	19.022	Up-regulation
AGC_Akt_AKT2_ST	Q04656	ATP7A	P31751	AKT2	S272	P271T	271	Missense	proximal	-1	no	23.452	23.747	EPSD	TCGA;ICGC;COSMIC	19.022	Up-regulation
AGC_Akt_AKT2_ST	Q04656	ATP7A	P31751	AKT2	T274	Y273C	273	Missense	proximal	-1	no	26.304	25.254	EPSD	TCGA;ICGC	19.022	Down-regulation
AGC_Akt_AKT2_ST	Q04656	ATP7A	P31751	AKT2	T274	P271T	271	Missense	distal	-3	no	26.304	19.973	EPSD	TCGA;ICGC;COSMIC	19.022	Down-regulation
AGC_Akt_AKT2_ST	Q04656	ATP7A	P31751	AKT2	S339	E336K	336	Missense	distal	-3	no	16.044	24.552	EPSD	TCGA;ICGC;COSMIC	19.022	Gain
AGC_Akt_AKT2_ST	Q04656	ATP7A	P31751	AKT2	S360	S353R	353	Missense	distal	-7	no	21.226	21.026	EPSD	TCGA;ICGC;COSMIC	19.022	Down-regulation
AGC_Akt_AKT2_ST	Q04656	ATP7A	P31751	AKT2	S360	L363I	363	Missense	distal	3	no	21.226	21.237	EPSD	TCGA;ICGC;COSMIC	19.022	Up-regulation
AGC_Akt_AKT2_ST	Q04656	ATP7A	P31751	AKT2	S360	P367H	367	Missense	distal	7	no	21.226	21.449	EPSD	TCGA;ICGC;COSMIC	19.022	Up-regulation
AGC_Akt_AKT2_ST	Q04656	ATP7A	P31751	AKT2	S639	D635Y	635	Missense	distal	-4	no	24.731	24.483	EPSD	TCGA;ICGC;COSMIC	19.022	Down-regulation
AGC_Akt_AKT2_ST	Q04656	ATP7A	P31751	AKT2	S639	R636W	636	Missense	distal	-3	no	24.731	9.002	EPSD	TCGA;ICGC;COSMIC;CCLE	19.022	Loss
AGC_Akt_AKT2_ST	Q04656	ATP7A	P31751	AKT2	S1146	V1148F	1148	Missense	proximal	2	no	22.345	23.160	EPSD	TCGA;COSMIC	19.022	Up-regulation
AGC_Akt_AKT2_ST	Q04656	ATP7A	P31751	AKT2	S1146	D1151H	1151	Missense	distal	5	no	22.345	23.224	EPSD	TCGA;COSMIC	19.022	Up-regulation
AGC_Akt_AKT2_ST	Q04656	ATP7A	P31751	AKT2	S1146	A1145P	1145	Missense	proximal	-1	no	22.345	21.589	EPSD	TCGA;COSMIC	19.022	Down-regulation
AGC_Akt_AKT2_ST	Q04656	ATP7A	P31751	AKT2	S1146	D1139Y	1139	Missense	distal	-7	no	22.345	22.232	EPSD	TCGA	19.022	Down-regulation
AGC_Akt_AKT2_ST	Q04656	ATP7A	P31751	AKT2	S1424	R1423Q	1423	Missense	proximal	-1	no	26.368	25.889	PhosphoSitePlus;EPSD	TCGA;COSMIC	19.022	Down-regulation
AGC_Akt_AKT2_ST	Q04656	ATP7A	P31751	AKT2	S1424	P1431H	1431	Missense	distal	7	no	26.368	26.591	PhosphoSitePlus;EPSD	TCGA	19.022	Up-regulation
AGC_Akt_AKT2_ST	Q04656	ATP7A	P31751	AKT2	S1424	Y1418D	1418	Missense	distal	-6	no	26.368	26.422	PhosphoSitePlus;EPSD	TCGA;COSMIC	19.022	Up-regulation
AGC_Akt_AKT2_ST	Q04656	ATP7A	P31751	AKT2	S1424	I1426M	1426	Missense	proximal	2	no	26.368	25.936	PhosphoSitePlus;EPSD	TCGA;COSMIC	19.022	Down-regulation
AGC_Akt_AKT2_ST	Q04656	ATP7A	P31751	AKT2	S1424	K1429N	1429	Missense	distal	5	no	26.368	25.943	PhosphoSitePlus;EPSD	TCGA;COSMIC	19.022	Down-regulation
AGC_Akt_AKT2_ST	Q04656	ATP7A	P31751	AKT2	S1424	S1424N	1424	Missense	central	0	yes	26.368	0.000	PhosphoSitePlus;EPSD	TCGA;COSMIC	19.022	Loss
AGC_Akt_AKT2_ST	Q04656	ATP7A	P31751	AKT2	S1463	S1466P	1466	Missense	distal	3	no	28.373	29.048	EPSD;PhosphoSitePlus	TCGA;COSMIC	19.022	Up-regulation
AGC_Akt_AKT2_ST	Q04656	ATP7A	P31751	AKT2	S1463	N1458D	1458	Missense	distal	-5	no	28.373	10.730	EPSD;PhosphoSitePlus	TCGA;COSMIC	19.022	Loss
AGC_Akt_AKT2_ST	Q04656	ATP7A	P31751	AKT2	S1466	S1466P	1466	Missense	central	0	yes	28.475	0.000	EPSD;PhosphoSitePlus	TCGA;COSMIC	19.022	Loss
AGC_Akt_AKT2_ST	Q04656	ATP7A	P31751	AKT2	S1466	R1472H	1472	Missense	distal	6	no	28.475	27.192	EPSD;PhosphoSitePlus	TCGA;COSMIC	19.022	Down-regulation
AGC_Akt_AKT2_ST	Q04656	ATP7A	P31751	AKT2	S1466	R1472C	1472	Missense	distal	6	no	28.475	25.826	EPSD;PhosphoSitePlus	TCGA;COSMIC	19.022	Down-regulation
AGC_Akt_AKT2_ST	Q04656	ATP7A	P31751	AKT2	T1479	L1474Q	1474	Missense	distal	-5	no	17.865	21.256	EPSD	TCGA;COSMIC	19.022	Gain
AGC_Akt_AKT2_ST	Q13835	PKP1	P31751	AKT2	S21	C14R	14	Missense	distal	-7	no	20.662	19.796	EPSD	TCGA;ICGC;COSMIC	19.022	Down-regulation
AGC_Akt_AKT2_ST	Q13835	PKP1	P31751	AKT2	S21	L25S	25	Missense	distal	4	no	20.662	20.454	EPSD	TCGA;ICGC	19.022	Down-regulation
AGC_Akt_AKT2_ST	Q13835	PKP1	P31751	AKT2	S142	G141V	141	Missense	proximal	-1	no	24.069	25.085	EPSD	TCGA;ICGC;COSMIC;GDSC;CCLE	19.022	Up-regulation
AGC_Akt_AKT2_ST	Q13835	PKP1	P31751	AKT2	S174	R168H	168	Missense	distal	-6	no	20.266	20.536	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	19.022	Up-regulation
AGC_Akt_AKT2_ST	Q13835	PKP1	P31751	AKT2	S174	R168C	168	Missense	distal	-6	no	20.266	21.065	EPSD;PhosphoSitePlus	TCGA;ICGC	19.022	Up-regulation
AGC_Akt_AKT2_ST	Q13835	PKP1	P31751	AKT2	S188	R183C	183	Missense	distal	-5	no	27.531	3.709	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	19.022	Loss
AGC_Akt_AKT2_ST	Q13835	PKP1	P31751	AKT2	S188	R183H	183	Missense	distal	-5	no	27.531	15.657	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	19.022	Loss
AGC_Akt_AKT2_ST	Q13835	PKP1	P31751	AKT2	S205	S208F	208	Missense	distal	3	no	20.966	22.179	EPSD	TCGA;ICGC;COSMIC	19.022	Up-regulation
AGC_Akt_AKT2_ST	Q13835	PKP1	P31751	AKT2	S205	R202C	202	Missense	distal	-3	no	20.966	-13.043	EPSD	TCGA;ICGC;COSMIC;GDSC;CCLE	19.022	Loss
AGC_Akt_AKT2_ST	Q13835	PKP1	P31751	AKT2	T511	E507D	507	Missense	distal	-4	no	21.951	22.404	EPSD	TCGA;COSMIC	19.022	Up-regulation
AGC_Akt_AKT2_ST	Q13835	PKP1	P31751	AKT2	T511	T511A	511	Missense	central	0	yes	21.951	0.000	EPSD	TCGA;ICGC;COSMIC	19.022	Loss
AGC_Akt_AKT2_ST	Q99683	MAP3K5	P31751	AKT2	S83	R80Q	80	Missense	distal	-3	no	33.303	24.618	PhosphoSitePlus	TCGA	19.022	Down-regulation
AGC_Akt_AKT2_ST	Q99683	MAP3K5	P31751	AKT2	S461	K466R	466	Missense	distal	5	no	20.351	20.608	EPSD	TCGA;ICGC	19.022	Up-regulation
AGC_Akt_AKT2_ST	Q99683	MAP3K5	P31751	AKT2	S613	S615C	615	Missense	proximal	2	no	22.392	23.568	EPSD	TCGA;COSMIC	19.022	Up-regulation
AGC_Akt_AKT2_ST	Q99683	MAP3K5	P31751	AKT2	S613	S607C	607	Missense	distal	-6	no	22.392	23.065	EPSD	TCGA;COSMIC	19.022	Up-regulation
AGC_Akt_AKT2_ST	Q99683	MAP3K5	P31751	AKT2	S613	S613N	613	Missense	central	0	yes	22.392	0.000	EPSD	TCGA;COSMIC	19.022	Loss
AGC_Akt_AKT2_ST	Q99683	MAP3K5	P31751	AKT2	S613	E618K	618	Missense	distal	5	no	22.392	21.872	EPSD	TCGA;ICGC;COSMIC	19.022	Down-regulation
AGC_Akt_AKT2_ST	Q99683	MAP3K5	P31751	AKT2	S613	R620I	620	Missense	distal	7	no	22.392	21.875	EPSD	TCGA;ICGC;COSMIC	19.022	Down-regulation
AGC_Akt_AKT2_ST	Q99683	MAP3K5	P31751	AKT2	S613	V609F	609	Missense	distal	-4	no	22.392	22.890	EPSD	TCGA;ICGC;COSMIC	19.022	Up-regulation
AGC_Akt_AKT2_ST	Q99683	MAP3K5	P31751	AKT2	S906	P901L	901	Missense	distal	-5	no	19.298	15.671	EPSD	TCGA;COSMIC	19.022	Loss
AGC_Akt_AKT2_ST	Q99683	MAP3K5	P31751	AKT2	S906	A913S	913	Missense	distal	7	no	19.298	19.062	EPSD	TCGA;COSMIC	19.022	Down-regulation
AGC_Akt_AKT2_ST	Q99683	MAP3K5	P31751	AKT2	S966	S966F	966	Missense	central	0	yes	20.579	0.000	EPSD	TCGA;COSMIC;CCLE	19.022	Loss
AGC_Akt_AKT2_ST	Q99683	MAP3K5	P31751	AKT2	S966	P968L	968	Missense	proximal	2	no	20.579	20.108	EPSD	TCGA;COSMIC	19.022	Down-regulation
AGC_Akt_AKT2_ST	Q99683	MAP3K5	P31751	AKT2	T1059	V1066M	1066	Missense	distal	7	no	25.919	25.585	EPSD	TCGA;COSMIC	19.022	Down-regulation
AGC_Akt_AKT2_ST	Q99683	MAP3K5	P31751	AKT2	T1059	T1059M	1059	Missense	central	0	yes	25.919	0.000	EPSD	TCGA;COSMIC	19.022	Loss
AGC_Akt_AKT2_ST	Q99683	MAP3K5	P31751	AKT2	T1108	T1108I	1108	Missense	central	0	yes	19.466	0.000	EPSD	TCGA;ICGC	19.022	Loss
AGC_Akt_AKT2_ST	Q99683	MAP3K5	P31751	AKT2	T1108	R1103Q	1103	Missense	distal	-5	no	19.466	15.133	EPSD	TCGA;ICGC;COSMIC	19.022	Loss
AGC_Akt_AKT2_ST	Q99683	MAP3K5	P31751	AKT2	T1108	T1101I	1101	Missense	distal	-7	no	19.466	19.867	EPSD	TCGA;COSMIC	19.022	Up-regulation
AGC_Akt_AKT2_ST	Q99683	MAP3K5	P31751	AKT2	T1225	S1224N	1224	Missense	proximal	-1	no	18.824	19.137	EPSD	TCGA	19.022	Gain
AGC_Akt_AKT2_ST	O43464	HTRA2	P31751	AKT2	S13	R15W	15	Missense	proximal	2	no	25.953	27.519	EPSD	TCGA;ICGC;COSMIC	19.022	Up-regulation
AGC_Akt_AKT2_ST	O43464	HTRA2	P31751	AKT2	S13	W12C	12	Missense	proximal	-1	no	25.953	25.931	EPSD	TCGA;ICGC;COSMIC	19.022	Down-regulation
AGC_Akt_AKT2_ST	O43464	HTRA2	P31751	AKT2	S41	A37T	37	Missense	distal	-4	no	19.939	19.997	EPSD	TCGA;ICGC;COSMIC	19.022	Up-regulation
AGC_Akt_AKT2_ST	O43464	HTRA2	P31751	AKT2	S96	T90I	90	Missense	distal	-6	no	28.776	29.368	EPSD	TCGA;ICGC;COSMIC	19.022	Up-regulation
AGC_Akt_AKT2_ST	O43464	HTRA2	P31751	AKT2	S212	R207G	207	Missense	distal	-5	no	32.760	26.465	PhosphoSitePlus	TCGA;ICGC;COSMIC	19.022	Down-regulation
AGC_Akt_AKT2_ST	O43464	HTRA2	P31751	AKT2	S212	V219L	219	Missense	distal	7	no	32.760	31.985	PhosphoSitePlus	TCGA;ICGC;COSMIC	19.022	Down-regulation
AGC_Akt_AKT2_ST	O43464	HTRA2	P31751	AKT2	T242	Q235H	235	Missense	distal	-7	no	22.885	23.364	EPSD	TCGA;ICGC;COSMIC	19.022	Up-regulation
AGC_Akt_AKT2_ST	O43464	HTRA2	P31751	AKT2	T242	E238G	238	Missense	distal	-4	no	22.885	23.060	EPSD	TCGA;ICGC;COSMIC	19.022	Up-regulation
AGC_Akt_AKT2_ST	O43464	HTRA2	P31751	AKT2	S435	R432Q	432	Missense	distal	-3	no	26.851	18.166	EPSD	TCGA;COSMIC	19.022	Loss
AGC_Akt_AKT2_ST	O43464	HTRA2	P31751	AKT2	S435	A430V	430	Missense	distal	-5	no	26.851	23.272	EPSD	TCGA	19.022	Down-regulation
AGC_Akt_AKT2_ST	P00533	EGFR	P31751	AKT2	S229	R222C	222	Missense	distal	-7	no	28.687	29.553	PhosphoSitePlus	TCGA;COSMIC	19.022	Up-regulation
AGC_Akt_AKT2_ST	P00533	EGFR	P31751	AKT2	S229	S229C	229	Missense	central	0	yes	28.687	0.000	PhosphoSitePlus	TCGA;COSMIC	19.022	Loss
AGC_Akt_AKT2_ST	P00533	EGFR	P31751	AKT2	S229	C223Y	223	Missense	distal	-6	no	28.687	28.485	PhosphoSitePlus	TCGA;COSMIC	19.022	Down-regulation
AGC_Akt_AKT2_ST	P00533	EGFR	P31751	AKT2	S229	R222L	222	Missense	distal	-7	no	28.687	29.295	PhosphoSitePlus	TCGA;COSMIC	19.022	Up-regulation
AGC_Akt_AKT2_ST	P00533	EGFR	P31751	AKT2	S229	S227F	227	Missense	proximal	-2	no	28.687	25.626	PhosphoSitePlus	TCGA;COSMIC	19.022	Down-regulation
AGC_Akt_AKT2_ST	P00533	EGFR	P31751	AKT2	S229	P228L	228	Missense	proximal	-1	no	28.687	28.099	PhosphoSitePlus	TCGA;COSMIC	19.022	Down-regulation
AGC_Akt_AKT2_ST	P00533	EGFR	P31751	AKT2	S229	N234S	234	Missense	distal	5	no	28.687	29.020	PhosphoSitePlus	TCGA;COSMIC	19.022	Up-regulation
AGC_Akt_AKT2_ST	P00533	EGFR	P31751	AKT2	S229	R224H	224	Missense	distal	-5	no	28.687	16.813	PhosphoSitePlus	TCGA;COSMIC	19.022	Loss
AGC_Akt_AKT2_ST	P00533	EGFR	P31751	AKT2	S246	R252C	252	Missense	distal	6	no	23.113	20.464	EPSD	TCGA;COSMIC	19.022	Down-regulation
AGC_Akt_AKT2_ST	P00533	EGFR	P31751	AKT2	S246	R252P	252	Missense	distal	6	no	23.113	21.715	EPSD	TCGA;COSMIC	19.022	Down-regulation
AGC_Akt_AKT2_ST	P00533	EGFR	P31751	AKT2	S246	C240Y	240	Missense	distal	-6	no	23.113	22.911	EPSD	TCGA;COSMIC	19.022	Down-regulation
AGC_Akt_AKT2_ST	P00533	EGFR	P31751	AKT2	S246	R252H	252	Missense	distal	6	no	23.113	21.830	EPSD	TCGA;COSMIC	19.022	Down-regulation
AGC_Akt_AKT2_ST	P00533	EGFR	P31751	AKT2	S246	D247N	247	Missense	proximal	1	no	23.113	22.800	EPSD	TCGA;COSMIC	19.022	Down-regulation
AGC_Akt_AKT2_ST	P00533	EGFR	P31751	AKT2	S246	G239S	239	Missense	distal	-7	no	23.113	22.997	EPSD	TCGA;COSMIC	19.022	Down-regulation
AGC_Akt_AKT2_ST	P00533	EGFR	P31751	AKT2	T678	R675W	675	Missense	distal	-3	no	22.642	6.913	EPSD	TCGA	19.022	Loss
AGC_Akt_AKT2_ST	P00533	EGFR	P31751	AKT2	T678	R677H	677	Missense	proximal	-1	no	22.642	21.868	EPSD	TCGA;COSMIC	19.022	Down-regulation
AGC_Akt_AKT2_ST	P00533	EGFR	P31751	AKT2	T678	R681M	681	Missense	distal	3	no	22.642	23.104	EPSD	TCGA	19.022	Up-regulation
AGC_Akt_AKT2_ST	P00533	EGFR	P31751	AKT2	T678	Q684H	684	Missense	distal	6	no	22.642	22.147	EPSD	TCGA	19.022	Down-regulation
AGC_Akt_AKT2_ST	P00533	EGFR	P31751	AKT2	T678	T678M	678	Missense	central	0	yes	22.642	0.000	EPSD	TCGA;GDSC;CCLE	19.022	Loss
AGC_Akt_AKT2_ST	P00533	EGFR	P31751	AKT2	T892	H893Y	893	Missense	proximal	1	no	20.261	20.323	EPSD	TCGA;COSMIC	19.022	Up-regulation
AGC_Akt_AKT2_ST	P00533	EGFR	P31751	AKT2	T892	Y891C	891	Missense	proximal	-1	no	20.261	19.212	EPSD	TCGA;COSMIC	19.022	Down-regulation
AGC_Akt_AKT2_ST	P00533	EGFR	P31751	AKT2	S925	E922K	922	Missense	distal	-3	no	11.912	20.420	EPSD	TCGA;COSMIC	19.022	Gain
AGC_Akt_AKT2_ST	P00533	EGFR	P31751	AKT2	S1030	T1032S	1032	Missense	proximal	2	no	20.862	20.350	EPSD	TCGA;COSMIC	19.022	Down-regulation
AGC_Akt_AKT2_ST	P00533	EGFR	P31751	AKT2	S1030	R1031Q	1031	Missense	proximal	1	no	20.862	21.700	EPSD	TCGA;COSMIC	19.022	Up-regulation
AGC_Akt_AKT2_ST	P00533	EGFR	P31751	AKT2	S1064	R1068Q	1068	Missense	distal	4	no	19.237	19.276	EPSD	TCGA;COSMIC	19.022	Up-regulation
AGC_Akt_AKT2_ST	P00533	EGFR	P31751	AKT2	S1120	P1123S	1123	Missense	distal	3	no	19.144	18.469	EPSD	TCGA;ICGC	19.022	Loss
AGC_Akt_AKT2_ST	P00533	EGFR	P31751	AKT2	S1204	A1201V	1201	Missense	distal	-3	no	30.072	25.606	EPSD	TCGA;ICGC;COSMIC	19.022	Down-regulation
AGC_Akt_AKT2_ST	P15311	EZR	P31751	AKT2	S249	S249F	249	Missense	central	0	yes	19.336	0.000	EPSD	TCGA;ICGC;COSMIC	19.022	Loss
AGC_Akt_AKT2_ST	P15311	EZR	P31751	AKT2	T299	P297L	297	Missense	proximal	-2	no	18.874	19.213	EPSD	TCGA;ICGC;COSMIC	19.022	Gain
AGC_Akt_AKT2_ST	P15311	EZR	P31751	AKT2	T299	E301D	301	Missense	proximal	2	no	18.874	20.041	EPSD	TCGA;ICGC	19.022	Gain
AGC_Akt_AKT2_ST	P15311	EZR	P31751	AKT2	T299	D298G	298	Missense	proximal	-1	no	18.874	19.116	EPSD	TCGA;ICGC	19.022	Gain
AGC_Akt_AKT2_ST	P15311	EZR	P31751	AKT2	T332	R330T	330	Missense	proximal	-2	no	24.052	20.598	EPSD	TCGA;ICGC;COSMIC	19.022	Down-regulation
AGC_Akt_AKT2_ST	P15311	EZR	P31751	AKT2	S535	L538V	538	Missense	distal	3	no	20.541	19.791	EPSD	TCGA;ICGC;COSMIC	19.022	Down-regulation
AGC_Akt_AKT2_ST	P15311	EZR	P31751	AKT2	S535	A541V	541	Missense	distal	6	no	20.541	20.877	EPSD	TCGA;ICGC;COSMIC	19.022	Up-regulation
AGC_Akt_AKT2_ST	P15311	EZR	P31751	AKT2	T567	R562Q	562	Missense	distal	-5	no	27.259	22.926	PhosphoSitePlus	TCGA;ICGC	19.022	Down-regulation
AGC_Akt_AKT2_ST	P15311	EZR	P31751	AKT2	T567	R569Q	569	Missense	proximal	2	no	27.259	27.778	PhosphoSitePlus	TCGA;ICGC;COSMIC	19.022	Up-regulation
AGC_Akt_AKT2_ST	Q9Y3M2	CBY1	P31751	AKT2	S20	P15S	15	Missense	distal	-5	no	23.158	20.095	PhosphoSitePlus	TCGA;ICGC;COSMIC	19.022	Down-regulation
AGC_Akt_AKT2_ST	Q9Y3M2	CBY1	P31751	AKT2	S20	S26A	26	Missense	distal	6	no	23.158	23.515	PhosphoSitePlus	TCGA;ICGC	19.022	Up-regulation
AGC_Akt_AKT2_ST	Q9Y3M2	CBY1	P31751	AKT2	S20	S26F	26	Missense	distal	6	no	23.158	22.189	PhosphoSitePlus	TCGA;ICGC;COSMIC	19.022	Down-regulation
AGC_Akt_AKT2_ST	P98170	XIAP	P31751	AKT2	S87	R84S	84	Missense	distal	-3	no	28.775	19.657	PhosphoSitePlus	TCGA;ICGC;COSMIC	19.022	Down-regulation
AGC_Akt_AKT2_ST	P98170	XIAP	P31751	AKT2	S87	H83Q	83	Missense	distal	-4	no	28.775	28.379	PhosphoSitePlus	TCGA;ICGC;COSMIC	19.022	Down-regulation
AGC_Akt_AKT2_ST	P98170	XIAP	P31751	AKT2	S261	M262I	262	Missense	proximal	1	no	20.020	20.662	EPSD	TCGA;ICGC;COSMIC	19.022	Up-regulation
AGC_Akt_AKT2_ST	P98170	XIAP	P31751	AKT2	S261	R258I	258	Missense	distal	-3	no	20.020	12.615	EPSD	TCGA;ICGC;COSMIC	19.022	Loss
AGC_Akt_AKT2_ST	P98170	XIAP	P31751	AKT2	S261	L256I	256	Missense	distal	-5	no	20.020	22.021	EPSD	TCGA;ICGC;COSMIC	19.022	Up-regulation
AGC_Akt_AKT2_ST	Q92908	GATA6	P31751	AKT2	S33	P36L	36	Missense	distal	3	no	27.560	27.675	EPSD	TCGA;ICGC;COSMIC	19.022	Up-regulation
AGC_Akt_AKT2_ST	Q92908	GATA6	P31751	AKT2	S37	P36L	36	Missense	proximal	-1	no	21.620	21.032	EPSD	TCGA;ICGC;COSMIC	19.022	Down-regulation
AGC_Akt_AKT2_ST	Q92908	GATA6	P31751	AKT2	S436	R439W	439	Missense	distal	3	no	29.593	31.216	EPSD	TCGA;ICGC;COSMIC	19.022	Up-regulation
AGC_Akt_AKT2_ST	Q14315	FLNC	P31751	AKT2	T423	R420W	420	Missense	distal	-3	no	21.423	5.695	EPSD	TCGA;ICGC;COSMIC	19.022	Loss
AGC_Akt_AKT2_ST	Q14315	FLNC	P31751	AKT2	T423	R420Q	420	Missense	distal	-3	no	21.423	12.738	EPSD	TCGA;ICGC;COSMIC;GDSC	19.022	Loss
AGC_Akt_AKT2_ST	Q14315	FLNC	P31751	AKT2	S1545	D1538H	1538	Missense	distal	-7	no	19.413	19.266	EPSD	TCGA;ICGC;COSMIC	19.022	Down-regulation
AGC_Akt_AKT2_ST	Q14315	FLNC	P31751	AKT2	S1545	A1551T	1551	Missense	distal	6	no	19.413	19.014	EPSD	TCGA;ICGC;COSMIC	19.022	Loss
AGC_Akt_AKT2_ST	Q14315	FLNC	P31751	AKT2	S1545	D1538E	1538	Missense	distal	-7	no	19.413	18.813	EPSD	TCGA;ICGC;COSMIC	19.022	Loss
AGC_Akt_AKT2_ST	Q14315	FLNC	P31751	AKT2	S1545	D1538N	1538	Missense	distal	-7	no	19.413	19.034	EPSD	TCGA;ICGC;COSMIC	19.022	Down-regulation
AGC_Akt_AKT2_ST	Q14315	FLNC	P31751	AKT2	S1545	G1546D	1546	Missense	proximal	1	no	19.413	19.507	EPSD	TCGA;ICGC;COSMIC	19.022	Up-regulation
AGC_Akt_AKT2_ST	Q14315	FLNC	P31751	AKT2	S1545	R1543W	1543	Missense	proximal	-2	no	19.413	14.240	EPSD	TCGA;ICGC;COSMIC	19.022	Loss
AGC_Akt_AKT2_ST	Q14315	FLNC	P31751	AKT2	S1940	I1946M	1946	Missense	distal	6	no	23.719	23.551	EPSD	TCGA;COSMIC	19.022	Down-regulation
AGC_Akt_AKT2_ST	Q14315	FLNC	P31751	AKT2	S1940	H1936N	1936	Missense	distal	-4	no	23.719	23.385	EPSD	TCGA	19.022	Down-regulation
AGC_Akt_AKT2_ST	Q14315	FLNC	P31751	AKT2	S1940	P1938S	1938	Missense	proximal	-2	no	23.719	23.928	EPSD	TCGA;ICGC;COSMIC	19.022	Up-regulation
AGC_Akt_AKT2_ST	Q14315	FLNC	P31751	AKT2	S1985	S1985L	1985	Missense	central	0	yes	23.021	0.000	EPSD	TCGA;COSMIC;GDSC	19.022	Loss
AGC_Akt_AKT2_ST	Q14315	FLNC	P31751	AKT2	S1985	R1982C	1982	Missense	distal	-3	no	23.021	-10.988	EPSD	TCGA;ICGC;COSMIC	19.022	Loss
AGC_Akt_AKT2_ST	Q14315	FLNC	P31751	AKT2	S2004	R1999Q	1999	Missense	distal	-5	no	20.051	15.717	EPSD	TCGA;COSMIC	19.022	Loss
AGC_Akt_AKT2_ST	Q14315	FLNC	P31751	AKT2	S2004	K2008R	2008	Missense	distal	4	no	20.051	19.883	EPSD	TCGA;ICGC;COSMIC	19.022	Down-regulation
AGC_Akt_AKT2_ST	Q14315	FLNC	P31751	AKT2	S2146	S2152R	2152	Missense	distal	6	no	18.990	20.203	EPSD	TCGA;ICGC;COSMIC	19.022	Gain
AGC_Akt_AKT2_ST	Q14315	FLNC	P31751	AKT2	S2146	P2145T	2145	Missense	proximal	-1	no	18.990	19.286	EPSD	TCGA;COSMIC	19.022	Gain
AGC_Akt_AKT2_ST	Q14315	FLNC	P31751	AKT2	S2146	R2140W	2140	Missense	distal	-6	no	18.990	19.804	EPSD	TCGA;COSMIC	19.022	Gain
AGC_Akt_AKT2_ST	Q14315	FLNC	P31751	AKT2	S2146	G2151S	2151	Missense	distal	5	no	18.990	19.335	EPSD	TCGA;ICGC;COSMIC;GDSC;CCLE	19.022	Gain
AGC_Akt_AKT2_ST	Q14315	FLNC	P31751	AKT2	T2179	R2176C	2176	Missense	distal	-3	no	19.607	-14.402	EPSD	TCGA;ICGC;COSMIC	19.022	Loss
AGC_Akt_AKT2_ST	Q14315	FLNC	P31751	AKT2	S2181	R2176C	2176	Missense	distal	-5	no	20.553	-3.269	EPSD	TCGA;ICGC;COSMIC	19.022	Loss
AGC_Akt_AKT2_ST	Q14315	FLNC	P31751	AKT2	S2181	T2188M	2188	Missense	distal	7	no	20.553	20.874	EPSD	TCGA;ICGC;COSMIC	19.022	Up-regulation
AGC_Akt_AKT2_ST	Q14315	FLNC	P31751	AKT2	S2233	Q2240P	2240	Missense	distal	7	no	35.073	34.736	PhosphoSitePlus	TCGA;ICGC;COSMIC	19.022	Down-regulation
AGC_Akt_AKT2_ST	Q14315	FLNC	P31751	AKT2	S2233	R2228W	2228	Missense	distal	-5	no	35.073	23.789	PhosphoSitePlus	TCGA;ICGC;COSMIC	19.022	Down-regulation
AGC_Akt_AKT2_ST	Q14315	FLNC	P31751	AKT2	S2233	R2228Q	2228	Missense	distal	-5	no	35.073	30.740	PhosphoSitePlus	TCGA;COSMIC;GDSC;CCLE	19.022	Down-regulation
AGC_Akt_AKT2_ST	Q14315	FLNC	P31751	AKT2	S2233	G2227D	2227	Missense	distal	-6	no	35.073	35.365	PhosphoSitePlus	TCGA;COSMIC	19.022	Up-regulation
AGC_Akt_AKT2_ST	Q14315	FLNC	P31751	AKT2	S2233	L2226P	2226	Missense	distal	-7	no	35.073	34.969	PhosphoSitePlus	TCGA;ICGC;COSMIC	19.022	Down-regulation
AGC_Akt_AKT2_ST	Q14315	FLNC	P31751	AKT2	S2256	S2258L	2258	Missense	proximal	2	no	18.243	19.201	EPSD	TCGA;COSMIC;GDSC;CCLE	19.022	Gain
AGC_Akt_AKT2_ST	Q14315	FLNC	P31751	AKT2	S2256	T2251P	2251	Missense	distal	-5	no	18.243	21.406	EPSD	TCGA;COSMIC	19.022	Gain
AGC_Akt_AKT2_ST	Q14315	FLNC	P31751	AKT2	S2395	H2391Y	2391	Missense	distal	-4	no	19.748	19.726	EPSD	TCGA;COSMIC	19.022	Down-regulation
AGC_Akt_AKT2_ST	Q14315	FLNC	P31751	AKT2	S2395	P2393S	2393	Missense	proximal	-2	no	19.748	19.956	EPSD	TCGA;ICGC;COSMIC	19.022	Up-regulation
AGC_Akt_AKT2_ST	Q14315	FLNC	P31751	AKT2	S2395	D2389N	2389	Missense	distal	-6	no	19.748	19.247	EPSD	TCGA;ICGC;COSMIC;GDSC;CCLE	19.022	Down-regulation
AGC_Akt_AKT2_ST	Q14315	FLNC	P31751	AKT2	T2414	G2420V	2420	Missense	distal	6	no	18.730	19.699	EPSD	TCGA;ICGC	19.022	Gain
AGC_Akt_AKT2_ST	Q14315	FLNC	P31751	AKT2	T2414	R2410C	2410	Missense	distal	-4	no	18.730	19.459	EPSD	TCGA;ICGC;COSMIC;GDSC;CCLE	19.022	Gain
AGC_Akt_AKT2_ST	Q14315	FLNC	P31751	AKT2	T2446	D2441N	2441	Missense	distal	-5	no	4.080	21.722	EPSD	TCGA;ICGC;COSMIC	19.022	Gain
AGC_Akt_AKT2_ST	Q14315	FLNC	P31751	AKT2	S2624	S2626N	2626	Missense	proximal	2	no	21.774	22.462	EPSD	TCGA;COSMIC	19.022	Up-regulation
AGC_Akt_AKT2_ST	Q14315	FLNC	P31751	AKT2	S2626	S2626N	2626	Missense	central	0	yes	24.793	0.000	EPSD	TCGA;COSMIC	19.022	Loss
AGC_Akt_AKT2_ST	Q14315	FLNC	P31751	AKT2	S2646	R2641W	2641	Missense	distal	-5	no	20.213	8.929	EPSD	TCGA;COSMIC	19.022	Loss
AGC_Akt_AKT2_ST	Q14315	FLNC	P31751	AKT2	S2646	R2641Q	2641	Missense	distal	-5	no	20.213	15.880	EPSD	TCGA	19.022	Loss
AGC_Akt_AKT2_ST	Q14315	FLNC	P31751	AKT2	S2646	P2643T	2643	Missense	distal	-3	no	20.213	13.883	EPSD	TCGA;ICGC;COSMIC	19.022	Loss
AGC_Akt_AKT2_ST	Q14315	FLNC	P31751	AKT2	S2646	A2648V	2648	Missense	proximal	2	no	20.213	20.055	EPSD	TCGA;COSMIC	19.022	Down-regulation
AGC_Akt_AKT2_ST	Q14315	FLNC	P31751	AKT2	S2646	R2641L	2641	Missense	distal	-5	no	20.213	12.489	EPSD	TCGA;COSMIC	19.022	Loss
AGC_Akt_AKT2_ST	P03372	ESR1	P31751	AKT2	S167	A166S	166	Missense	proximal	-1	no	34.641	33.968	PhosphoSitePlus	TCGA;ICGC;COSMIC	19.022	Down-regulation
AGC_Akt_AKT2_ST	P03372	ESR1	P31751	AKT2	S167	K171M	171	Missense	distal	4	no	34.641	34.690	PhosphoSitePlus	TCGA;ICGC;COSMIC	19.022	Up-regulation
AGC_Akt_AKT2_ST	P03372	ESR1	P31751	AKT2	S201	H196R	196	Missense	distal	-5	no	14.635	26.509	EPSD	TCGA;ICGC;COSMIC	19.022	Gain
AGC_Akt_AKT2_ST	P03372	ESR1	P31751	AKT2	S236	K235N	235	Missense	proximal	-1	no	31.635	31.983	EPSD	TCGA;ICGC;COSMIC	19.022	Up-regulation
AGC_Akt_AKT2_ST	P03372	ESR1	P31751	AKT2	S236	A239S	239	Missense	distal	3	no	31.635	31.142	EPSD	TCGA;ICGC;COSMIC	19.022	Down-regulation
AGC_Akt_AKT2_ST	P03372	ESR1	P31751	AKT2	S236	R243H	243	Missense	distal	7	no	31.635	31.425	EPSD	TCGA;ICGC;COSMIC	19.022	Down-regulation
AGC_Akt_AKT2_ST	P03372	ESR1	P31751	AKT2	S236	R243C	243	Missense	distal	7	no	31.635	30.664	EPSD	TCGA;ICGC;COSMIC	19.022	Down-regulation
AGC_Akt_AKT2_ST	P03372	ESR1	P31751	AKT2	S236	C240Y	240	Missense	distal	4	no	31.635	31.515	EPSD	TCGA;ICGC;COSMIC	19.022	Down-regulation
AGC_Akt_AKT2_ST	P03372	ESR1	P31751	AKT2	S282	G278C	278	Missense	distal	-4	no	21.270	21.625	EPSD	TCGA;ICGC;COSMIC	19.022	Up-regulation
AGC_Akt_AKT2_ST	P03372	ESR1	P31751	AKT2	S282	M286T	286	Missense	distal	4	no	21.270	21.248	EPSD	TCGA;ICGC;COSMIC	19.022	Down-regulation
AGC_Akt_AKT2_ST	Q9H0H5	RACGAP1	P31751	AKT2	S144	S151Y	151	Missense	distal	7	no	24.122	23.697	EPSD	TCGA;ICGC;COSMIC	19.022	Down-regulation
AGC_Akt_AKT2_ST	Q9H0H5	RACGAP1	P31751	AKT2	S185	R184C	184	Missense	proximal	-1	no	24.872	22.718	EPSD	TCGA;ICGC;COSMIC	19.022	Down-regulation
AGC_Akt_AKT2_ST	Q9H0H5	RACGAP1	P31751	AKT2	S187	R184C	184	Missense	distal	-3	no	22.931	-11.078	EPSD	TCGA;ICGC;COSMIC	19.022	Loss
AGC_Akt_AKT2_ST	Q9H0H5	RACGAP1	P31751	AKT2	S187	S185T	185	Missense	proximal	-2	no	22.931	22.057	EPSD	TCGA;ICGC;COSMIC	19.022	Down-regulation
AGC_Akt_AKT2_ST	Q9H0H5	RACGAP1	P31751	AKT2	S187	G193D	193	Missense	distal	6	no	22.931	22.031	EPSD	TCGA;ICGC;COSMIC	19.022	Down-regulation
AGC_Akt_AKT2_ST	Q9H0H5	RACGAP1	P31751	AKT2	T249	R247M	247	Missense	proximal	-2	no	29.292	25.710	PhosphoSitePlus	TCGA;ICGC	19.022	Down-regulation
AGC_Akt_AKT2_ST	Q9H0H5	RACGAP1	P31751	AKT2	T405	L409V	409	Missense	distal	4	no	26.507	26.437	EPSD	TCGA;ICGC;COSMIC	19.022	Down-regulation
AGC_Akt_AKT2_ST	Q9H0H5	RACGAP1	P31751	AKT2	T405	S410C	410	Missense	distal	5	no	26.507	24.988	EPSD	TCGA;ICGC;COSMIC	19.022	Down-regulation
AGC_Akt_AKT2_ST	Q9H0H5	RACGAP1	P31751	AKT2	T405	E398Q	398	Missense	distal	-7	no	26.507	26.481	EPSD	TCGA;ICGC;COSMIC	19.022	Down-regulation
AGC_Akt_AKT2_ST	Q9H0H5	RACGAP1	P31751	AKT2	T405	K411N	411	Missense	distal	6	no	26.507	26.207	EPSD	TCGA;ICGC;COSMIC	19.022	Down-regulation
AGC_Akt_AKT2_ST	Q9H0H5	RACGAP1	P31751	AKT2	S592	R597K	597	Missense	distal	5	no	21.870	21.613	EPSD	TCGA;ICGC	19.022	Down-regulation
AGC_Akt_AKT2_ST	Q9H0H5	RACGAP1	P31751	AKT2	S600	P607L	607	Missense	distal	7	no	22.113	21.808	EPSD	TCGA;ICGC;COSMIC	19.022	Down-regulation
AGC_Akt_AKT2_ST	Q9H0H5	RACGAP1	P31751	AKT2	S600	R597K	597	Missense	distal	-3	no	22.113	15.151	EPSD	TCGA;ICGC	19.022	Loss
AGC_Akt_AKT2_ST	Q9H0H5	RACGAP1	P31751	AKT2	S611	S613T	613	Missense	proximal	2	no	19.326	19.839	EPSD	TCGA;ICGC;COSMIC	19.022	Up-regulation
AGC_Akt_AKT2_ST	Q9H0H5	RACGAP1	P31751	AKT2	S611	P607L	607	Missense	distal	-4	no	19.326	19.734	EPSD	TCGA;ICGC;COSMIC	19.022	Up-regulation
AGC_Akt_AKT2_ST	Q9H0H5	RACGAP1	P31751	AKT2	S611	S613N	613	Missense	proximal	2	no	19.326	20.014	EPSD	TCGA;ICGC;COSMIC	19.022	Up-regulation
AGC_Akt_AKT2_ST	Q9H0H5	RACGAP1	P31751	AKT2	T617	Q622K	622	Missense	distal	5	no	20.511	20.264	EPSD	TCGA;ICGC;COSMIC	19.022	Down-regulation
AGC_Akt_AKT2_ST	Q9H0H5	RACGAP1	P31751	AKT2	T617	S613N	613	Missense	distal	-4	no	20.511	20.359	EPSD	TCGA;ICGC;COSMIC	19.022	Down-regulation
AGC_Akt_AKT2_ST	O43516	WIPF1	P31751	AKT2	S135	A138V	138	Missense	distal	3	no	23.063	22.609	EPSD	TCGA;ICGC;COSMIC	19.022	Down-regulation
AGC_Akt_AKT2_ST	O43516	WIPF1	P31751	AKT2	S135	F141L	141	Missense	distal	6	no	23.063	23.671	EPSD	TCGA;ICGC;COSMIC	19.022	Up-regulation
AGC_Akt_AKT2_ST	O43516	WIPF1	P31751	AKT2	T136	A138V	138	Missense	proximal	2	no	19.401	19.243	EPSD	TCGA;ICGC;COSMIC	19.022	Down-regulation
AGC_Akt_AKT2_ST	O43516	WIPF1	P31751	AKT2	T136	F141L	141	Missense	distal	5	no	19.401	19.175	EPSD	TCGA;ICGC;COSMIC	19.022	Down-regulation
AGC_Akt_AKT2_ST	O43516	WIPF1	P31751	AKT2	S137	A138V	138	Missense	proximal	1	no	22.220	20.792	EPSD	TCGA;ICGC;COSMIC	19.022	Down-regulation
AGC_Akt_AKT2_ST	O43516	WIPF1	P31751	AKT2	S137	F141L	141	Missense	distal	4	no	22.220	22.051	EPSD	TCGA;ICGC;COSMIC	19.022	Down-regulation
AGC_Akt_AKT2_ST	O43516	WIPF1	P31751	AKT2	S145	A138V	138	Missense	distal	-7	no	27.081	26.936	EPSD	TCGA;ICGC;COSMIC	19.022	Down-regulation
AGC_Akt_AKT2_ST	O43516	WIPF1	P31751	AKT2	S145	F141L	141	Missense	distal	-4	no	27.081	26.935	EPSD	TCGA;ICGC;COSMIC	19.022	Down-regulation
AGC_Akt_AKT2_ST	O43516	WIPF1	P31751	AKT2	S154	G160C	160	Missense	distal	6	no	30.343	29.184	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	19.022	Down-regulation
AGC_Akt_AKT2_ST	O43516	WIPF1	P31751	AKT2	S214	G216W	216	Missense	proximal	2	no	21.008	22.218	EPSD	TCGA;ICGC;COSMIC	19.022	Up-regulation
AGC_Akt_AKT2_ST	O43516	WIPF1	P31751	AKT2	S214	T218S	218	Missense	distal	4	no	21.008	20.895	EPSD	TCGA;ICGC;COSMIC	19.022	Down-regulation
AGC_Akt_AKT2_ST	O43516	WIPF1	P31751	AKT2	S214	P215L	215	Missense	proximal	1	no	21.008	20.184	EPSD	TCGA;ICGC;COSMIC	19.022	Down-regulation
AGC_Akt_AKT2_ST	O43516	WIPF1	P31751	AKT2	S214	P213L	213	Missense	proximal	-1	no	21.008	20.420	EPSD	TCGA;ICGC;COSMIC	19.022	Down-regulation
AGC_Akt_AKT2_ST	O43516	WIPF1	P31751	AKT2	S214	P213S	213	Missense	proximal	-1	no	21.008	21.091	EPSD	TCGA;ICGC;COSMIC	19.022	Up-regulation
AGC_Akt_AKT2_ST	O43516	WIPF1	P31751	AKT2	S214	G216E	216	Missense	proximal	2	no	21.008	20.638	EPSD	TCGA;ICGC	19.022	Down-regulation
AGC_Akt_AKT2_ST	O43516	WIPF1	P31751	AKT2	S214	G216R	216	Missense	proximal	2	no	21.008	20.652	EPSD	TCGA;ICGC;COSMIC	19.022	Down-regulation
AGC_Akt_AKT2_ST	O43516	WIPF1	P31751	AKT2	S214	Q212K	212	Missense	proximal	-2	no	21.008	20.344	EPSD	TCGA;ICGC;COSMIC	19.022	Down-regulation
AGC_Akt_AKT2_ST	O43516	WIPF1	P31751	AKT2	S238	S244L	244	Missense	distal	6	no	23.282	22.921	EPSD	TCGA;ICGC;COSMIC	19.022	Down-regulation
AGC_Akt_AKT2_ST	O43516	WIPF1	P31751	AKT2	S238	G231E	231	Missense	distal	-7	no	23.282	23.092	EPSD	TCGA;ICGC;COSMIC	19.022	Down-regulation
AGC_Akt_AKT2_ST	O43516	WIPF1	P31751	AKT2	S238	R236H	236	Missense	proximal	-2	no	23.282	20.383	EPSD	TCGA;ICGC;COSMIC	19.022	Down-regulation
AGC_Akt_AKT2_ST	O43516	WIPF1	P31751	AKT2	S242	S244L	244	Missense	proximal	2	no	18.232	19.190	EPSD	TCGA;ICGC;COSMIC	19.022	Gain
AGC_Akt_AKT2_ST	O43516	WIPF1	P31751	AKT2	S244	P250L	250	Missense	distal	6	no	21.360	21.185	EPSD	TCGA;ICGC;COSMIC	19.022	Down-regulation
AGC_Akt_AKT2_ST	O43516	WIPF1	P31751	AKT2	S244	S244L	244	Missense	central	0	yes	21.360	0.000	EPSD	TCGA;ICGC;COSMIC	19.022	Loss
AGC_Akt_AKT2_ST	O43516	WIPF1	P31751	AKT2	S296	T297A	297	Missense	proximal	1	no	23.836	23.734	EPSD	TCGA;ICGC;COSMIC	19.022	Down-regulation
AGC_Akt_AKT2_ST	O43516	WIPF1	P31751	AKT2	S296	P293L	293	Missense	distal	-3	no	23.836	22.016	EPSD	TCGA;ICGC;COSMIC	19.022	Down-regulation
AGC_Akt_AKT2_ST	O43516	WIPF1	P31751	AKT2	S296	N289S	289	Missense	distal	-7	no	23.836	23.689	EPSD	TCGA;ICGC;COSMIC	19.022	Down-regulation
AGC_Akt_AKT2_ST	O43516	WIPF1	P31751	AKT2	S301	A306V	306	Missense	distal	5	no	20.577	20.345	EPSD	TCGA;ICGC;COSMIC	19.022	Down-regulation
AGC_Akt_AKT2_ST	O43516	WIPF1	P31751	AKT2	S301	T297A	297	Missense	distal	-4	no	20.577	20.519	EPSD	TCGA;ICGC;COSMIC	19.022	Down-regulation
AGC_Akt_AKT2_ST	O43516	WIPF1	P31751	AKT2	S340	S343L	343	Missense	distal	3	no	22.692	23.483	EPSD	TCGA;ICGC;COSMIC	19.022	Up-regulation
AGC_Akt_AKT2_ST	O43516	WIPF1	P31751	AKT2	S340	R337Q	337	Missense	distal	-3	no	22.692	14.007	EPSD	TCGA;ICGC;COSMIC	19.022	Loss
AGC_Akt_AKT2_ST	O43516	WIPF1	P31751	AKT2	S342	S343L	343	Missense	proximal	1	no	20.655	20.762	EPSD	TCGA;ICGC;COSMIC	19.022	Up-regulation
AGC_Akt_AKT2_ST	O43516	WIPF1	P31751	AKT2	S342	R337Q	337	Missense	distal	-5	no	20.655	16.322	EPSD	TCGA;ICGC;COSMIC	19.022	Loss
AGC_Akt_AKT2_ST	O43516	WIPF1	P31751	AKT2	S354	P351L	351	Missense	distal	-3	no	21.719	19.900	EPSD	TCGA;ICGC;COSMIC	19.022	Down-regulation
AGC_Akt_AKT2_ST	O43516	WIPF1	P31751	AKT2	S354	G355D	355	Missense	proximal	1	no	21.719	21.814	EPSD	TCGA;ICGC;COSMIC	19.022	Up-regulation
AGC_Akt_AKT2_ST	O43516	WIPF1	P31751	AKT2	S354	R353H	353	Missense	proximal	-1	no	21.719	20.946	EPSD	TCGA;ICGC;COSMIC	19.022	Down-regulation
AGC_Akt_AKT2_ST	O43516	WIPF1	P31751	AKT2	S390	R393W	393	Missense	distal	3	no	18.189	19.812	EPSD	TCGA;ICGC;GDSC;CCLE	19.022	Gain
AGC_Akt_AKT2_ST	O43516	WIPF1	P31751	AKT2	S392	R393W	393	Missense	proximal	1	no	20.440	23.741	EPSD	TCGA;ICGC;GDSC;CCLE	19.022	Up-regulation
AGC_Akt_AKT2_ST	O43516	WIPF1	P31751	AKT2	T398	R393W	393	Missense	distal	-5	no	27.716	16.432	PhosphoSitePlus;EPSD	TCGA;ICGC;GDSC;CCLE	19.022	Loss
AGC_Akt_AKT2_ST	O43516	WIPF1	P31751	AKT2	S405	V407E	407	Missense	proximal	2	no	21.647	20.922	EPSD	TCGA;ICGC;COSMIC	19.022	Down-regulation
AGC_Akt_AKT2_ST	O43516	WIPF1	P31751	AKT2	S412	V407E	407	Missense	distal	-5	no	17.733	20.026	EPSD	TCGA;ICGC;COSMIC	19.022	Gain
AGC_Akt_AKT2_ST	O43516	WIPF1	P31751	AKT2	S434	P429S	429	Missense	distal	-5	no	19.834	16.770	EPSD	TCGA;ICGC;COSMIC	19.022	Loss
AGC_Akt_AKT2_ST	O43516	WIPF1	P31751	AKT2	S434	N439H	439	Missense	distal	5	no	19.834	20.075	EPSD	TCGA;ICGC	19.022	Up-regulation
AGC_Akt_AKT2_ST	O43516	WIPF1	P31751	AKT2	T435	P429S	429	Missense	distal	-6	no	24.674	24.159	EPSD	TCGA;ICGC;COSMIC	19.022	Down-regulation
AGC_Akt_AKT2_ST	O43516	WIPF1	P31751	AKT2	T435	N439H	439	Missense	distal	4	no	24.674	24.677	EPSD	TCGA;ICGC	19.022	Up-regulation
AGC_Akt_AKT2_ST	O43516	WIPF1	P31751	AKT2	S488	G494C	494	Missense	distal	6	no	24.005	22.846	EPSD	TCGA	19.022	Down-regulation
AGC_Akt_AKT2_ST	O43516	WIPF1	P31751	AKT2	S488	E483K	483	Missense	distal	-5	no	24.005	27.385	EPSD	TCGA;ICGC;COSMIC	19.022	Up-regulation
AGC_Akt_AKT2_ST	O43516	WIPF1	P31751	AKT2	S488	R490Q	490	Missense	proximal	2	no	24.005	24.524	EPSD	TCGA;ICGC;COSMIC;CCLE	19.022	Up-regulation
AGC_Akt_AKT2_ST	Q96F86	EDC3	P31751	AKT2	S152	E147K	147	Missense	distal	-5	no	18.426	21.806	EPSD	TCGA;ICGC;COSMIC	19.022	Gain
AGC_Akt_AKT2_ST	Q96F86	EDC3	P31751	AKT2	S161	H168Y	168	Missense	distal	7	no	34.291	33.968	PhosphoSitePlus	TCGA;ICGC	19.022	Down-regulation
AGC_Akt_AKT2_ST	Q96F86	EDC3	P31751	AKT2	S161	S161F	161	Missense	central	0	yes	34.291	0.000	PhosphoSitePlus	TCGA;ICGC;COSMIC	19.022	Loss
AGC_Akt_AKT2_ST	Q96F86	EDC3	P31751	AKT2	S253	R259Q	259	Missense	distal	6	no	20.180	19.392	EPSD	TCGA;ICGC;COSMIC	19.022	Down-regulation
AGC_Akt_AKT2_ST	Q96F86	EDC3	P31751	AKT2	S253	E248K	248	Missense	distal	-5	no	20.180	23.560	EPSD	TCGA;ICGC;COSMIC	19.022	Up-regulation
AGC_Akt_AKT2_ST	Q99623	PHB2	P31751	AKT2	S91	G95C	95	Missense	distal	4	no	31.995	32.320	PhosphoSitePlus;EPSD	TCGA;ICGC;COSMIC	19.022	Up-regulation
AGC_Akt_AKT2_ST	Q99623	PHB2	P31751	AKT2	S92	G95C	95	Missense	distal	3	no	21.092	21.931	EPSD	TCGA;ICGC;COSMIC	19.022	Up-regulation
AGC_Akt_AKT2_ST	Q99623	PHB2	P31751	AKT2	S96	G95C	95	Missense	proximal	-1	no	19.548	19.127	EPSD	TCGA;ICGC;COSMIC	19.022	Down-regulation
AGC_Akt_AKT2_ST	Q99623	PHB2	P31751	AKT2	S96	N103S	103	Missense	distal	7	no	19.548	20.018	EPSD	TCGA;ICGC;COSMIC	19.022	Up-regulation
AGC_Akt_AKT2_ST	Q99623	PHB2	P31751	AKT2	T263	N269K	269	Missense	distal	6	no	19.475	19.776	EPSD	TCGA;COSMIC	19.022	Up-regulation
AGC_Akt_AKT2_ST	Q99623	PHB2	P31751	AKT2	T263	T263M	263	Missense	central	0	yes	19.475	0.000	EPSD	TCGA;COSMIC	19.022	Loss
AGC_Akt_AKT2_ST	Q92945	KHSRP	P31751	AKT2	S144	Y149C	149	Missense	distal	5	no	25.523	24.704	EPSD	TCGA;ICGC	19.022	Down-regulation
AGC_Akt_AKT2_ST	Q92945	KHSRP	P31751	AKT2	S193	R190C	190	Missense	distal	-3	no	28.142	-5.867	PhosphoSitePlus	TCGA;ICGC	19.022	Loss
AGC_Akt_AKT2_ST	Q92945	KHSRP	P31751	AKT2	S193	E199D	199	Missense	distal	6	no	28.142	26.474	PhosphoSitePlus	TCGA;ICGC;COSMIC	19.022	Down-regulation
AGC_Akt_AKT2_ST	Q92945	KHSRP	P31751	AKT2	S670	A676V	676	Missense	distal	6	no	21.412	21.747	EPSD	TCGA;ICGC;COSMIC	19.022	Up-regulation
AGC_Akt_AKT2_ST	O60331	PIP5K1C	P31751	AKT2	S355	L353H	353	Missense	proximal	-2	no	20.070	19.621	EPSD	TCGA;ICGC;COSMIC	19.022	Down-regulation
AGC_Akt_AKT2_ST	O60331	PIP5K1C	P31751	AKT2	S355	K351N	351	Missense	distal	-4	no	20.070	19.983	EPSD	TCGA;ICGC;COSMIC	19.022	Down-regulation
AGC_Akt_AKT2_ST	O60331	PIP5K1C	P31751	AKT2	S539	S541L	541	Missense	proximal	2	no	21.962	22.920	EPSD	TCGA;ICGC;COSMIC	19.022	Up-regulation
AGC_Akt_AKT2_ST	O60331	PIP5K1C	P31751	AKT2	S539	S534F	534	Missense	distal	-5	no	21.962	18.562	EPSD	TCGA;ICGC;COSMIC	19.022	Loss
AGC_Akt_AKT2_ST	O60331	PIP5K1C	P31751	AKT2	S539	P540S	540	Missense	proximal	1	no	21.962	21.032	EPSD	TCGA;ICGC;COSMIC	19.022	Down-regulation
AGC_Akt_AKT2_ST	O60331	PIP5K1C	P31751	AKT2	S539	R538Q	538	Missense	proximal	-1	no	21.962	21.483	EPSD	TCGA;ICGC;COSMIC	19.022	Down-regulation
AGC_Akt_AKT2_ST	O60331	PIP5K1C	P31751	AKT2	S539	R538W	538	Missense	proximal	-1	no	21.962	19.830	EPSD	TCGA;ICGC	19.022	Down-regulation
AGC_Akt_AKT2_ST	O60331	PIP5K1C	P31751	AKT2	S541	S541L	541	Missense	central	0	yes	25.896	0.000	EPSD	TCGA;ICGC;COSMIC	19.022	Loss
AGC_Akt_AKT2_ST	O60331	PIP5K1C	P31751	AKT2	S541	S534F	534	Missense	distal	-7	no	25.896	26.545	EPSD	TCGA;ICGC;COSMIC	19.022	Up-regulation
AGC_Akt_AKT2_ST	O60331	PIP5K1C	P31751	AKT2	S541	R548W	548	Missense	distal	7	no	25.896	24.728	EPSD	TCGA;ICGC;COSMIC	19.022	Down-regulation
AGC_Akt_AKT2_ST	O60331	PIP5K1C	P31751	AKT2	S541	R548Q	548	Missense	distal	7	no	25.896	25.800	EPSD	TCGA;ICGC	19.022	Down-regulation
AGC_Akt_AKT2_ST	O60331	PIP5K1C	P31751	AKT2	S541	P540S	540	Missense	proximal	-1	no	25.896	25.979	EPSD	TCGA;ICGC;COSMIC	19.022	Up-regulation
AGC_Akt_AKT2_ST	O60331	PIP5K1C	P31751	AKT2	S541	R538Q	538	Missense	distal	-3	no	25.896	17.211	EPSD	TCGA;ICGC;COSMIC	19.022	Loss
AGC_Akt_AKT2_ST	O60331	PIP5K1C	P31751	AKT2	S541	R538W	538	Missense	distal	-3	no	25.896	10.167	EPSD	TCGA;ICGC	19.022	Loss
AGC_Akt_AKT2_ST	O60331	PIP5K1C	P31751	AKT2	T543	S541L	541	Missense	proximal	-2	no	22.618	22.748	EPSD	TCGA;ICGC;COSMIC	19.022	Up-regulation
AGC_Akt_AKT2_ST	O60331	PIP5K1C	P31751	AKT2	T543	R548W	548	Missense	distal	5	no	22.618	20.829	EPSD	TCGA;ICGC;COSMIC	19.022	Down-regulation
AGC_Akt_AKT2_ST	O60331	PIP5K1C	P31751	AKT2	T543	R548Q	548	Missense	distal	5	no	22.618	22.608	EPSD	TCGA;ICGC	19.022	Down-regulation
AGC_Akt_AKT2_ST	O60331	PIP5K1C	P31751	AKT2	T543	P540S	540	Missense	distal	-3	no	22.618	19.777	EPSD	TCGA;ICGC;COSMIC	19.022	Down-regulation
AGC_Akt_AKT2_ST	O60331	PIP5K1C	P31751	AKT2	T543	R538Q	538	Missense	distal	-5	no	22.618	18.284	EPSD	TCGA;ICGC;COSMIC	19.022	Loss
AGC_Akt_AKT2_ST	O60331	PIP5K1C	P31751	AKT2	T543	R538W	538	Missense	distal	-5	no	22.618	11.334	EPSD	TCGA;ICGC	19.022	Loss
AGC_Akt_AKT2_ST	O60331	PIP5K1C	P31751	AKT2	T553	R551Q	551	Missense	proximal	-2	no	28.809	26.409	EPSD	TCGA;ICGC;COSMIC	19.022	Down-regulation
AGC_Akt_AKT2_ST	O60331	PIP5K1C	P31751	AKT2	T553	R548W	548	Missense	distal	-5	no	28.809	17.525	EPSD	TCGA;ICGC;COSMIC	19.022	Loss
AGC_Akt_AKT2_ST	O60331	PIP5K1C	P31751	AKT2	T553	R548Q	548	Missense	distal	-5	no	28.809	24.476	EPSD	TCGA;ICGC	19.022	Down-regulation
AGC_Akt_AKT2_ST	O60331	PIP5K1C	P31751	AKT2	T553	R551W	551	Missense	proximal	-2	no	28.809	23.636	EPSD	TCGA;ICGC;COSMIC	19.022	Down-regulation
AGC_Akt_AKT2_ST	O60331	PIP5K1C	P31751	AKT2	S555	R551Q	551	Missense	distal	-4	no	30.031	30.059	PhosphoSitePlus	TCGA;ICGC;COSMIC	19.022	Up-regulation
AGC_Akt_AKT2_ST	O60331	PIP5K1C	P31751	AKT2	S555	R548W	548	Missense	distal	-7	no	30.031	30.863	PhosphoSitePlus	TCGA;ICGC;COSMIC	19.022	Up-regulation
AGC_Akt_AKT2_ST	O60331	PIP5K1C	P31751	AKT2	S555	R548Q	548	Missense	distal	-7	no	30.031	30.131	PhosphoSitePlus	TCGA;ICGC	19.022	Up-regulation
AGC_Akt_AKT2_ST	O60331	PIP5K1C	P31751	AKT2	S555	R561S	561	Missense	distal	6	no	30.031	28.818	PhosphoSitePlus	TCGA;ICGC;COSMIC	19.022	Down-regulation
AGC_Akt_AKT2_ST	O60331	PIP5K1C	P31751	AKT2	S555	R561T	561	Missense	distal	6	no	30.031	28.776	PhosphoSitePlus	TCGA;ICGC;COSMIC	19.022	Down-regulation
AGC_Akt_AKT2_ST	O60331	PIP5K1C	P31751	AKT2	S555	R551W	551	Missense	distal	-4	no	30.031	30.746	PhosphoSitePlus	TCGA;ICGC;COSMIC	19.022	Up-regulation
AGC_Akt_AKT2_ST	O60331	PIP5K1C	P31751	AKT2	S650	D643N	643	Missense	distal	-7	no	19.210	18.831	EPSD	TCGA;ICGC	19.022	Loss
AGC_Akt_AKT2_ST	O60331	PIP5K1C	P31751	AKT2	S650	E644D	644	Missense	distal	-6	no	19.210	20.124	EPSD	TCGA;ICGC;COSMIC	19.022	Up-regulation
AGC_Akt_AKT2_ST	O60331	PIP5K1C	P31751	AKT2	S650	Y654C	654	Missense	distal	4	no	19.210	19.330	EPSD	TCGA;ICGC;COSMIC	19.022	Up-regulation
AGC_Akt_AKT2_ST	O60331	PIP5K1C	P31751	AKT2	S650	H653Y	653	Missense	distal	3	no	19.210	19.428	EPSD	TCGA;ICGC;COSMIC	19.022	Up-regulation
AGC_Akt_AKT2_ST	O60331	PIP5K1C	P31751	AKT2	S650	Y649H	649	Missense	proximal	-1	no	19.210	19.541	EPSD	TCGA;ICGC;COSMIC	19.022	Up-regulation
AGC_Akt_AKT2_ST	O60331	PIP5K1C	P31751	AKT2	S650	A656V	656	Missense	distal	6	no	19.210	19.546	EPSD	TCGA;ICGC;COSMIC;CCLE	19.022	Up-regulation
AGC_Akt_AKT2_ST	O60331	PIP5K1C	P31751	AKT2	S650	S646C	646	Missense	distal	-4	no	19.210	19.696	EPSD	TCGA;ICGC;COSMIC	19.022	Up-regulation
AGC_Akt_AKT2_ST	O15111	CHUK	P31751	AKT2	T23	R18W	18	Missense	distal	-5	no	34.368	23.084	PhosphoSitePlus	TCGA;ICGC;COSMIC	19.022	Down-regulation
AGC_Akt_AKT2_ST	O15111	CHUK	P31751	AKT2	T593	R599H	599	Missense	distal	6	no	20.968	19.685	EPSD	TCGA;ICGC;COSMIC	19.022	Down-regulation
AGC_Akt_AKT2_ST	P35222	CTNNB1	P31751	AKT2	T42	S45F	45	Missense	distal	3	no	18.061	19.274	EPSD	TCGA;COSMIC;GDSC;CCLE	19.022	Gain
AGC_Akt_AKT2_ST	P35222	CTNNB1	P31751	AKT2	T42	S37A	37	Missense	distal	-5	no	18.061	19.461	EPSD	TCGA;COSMIC;GDSC;CCLE	19.022	Gain
AGC_Akt_AKT2_ST	P35222	CTNNB1	P31751	AKT2	T42	S37P	37	Missense	distal	-5	no	18.061	21.125	EPSD	TCGA;COSMIC;GDSC;CCLE	19.022	Gain
AGC_Akt_AKT2_ST	P35222	CTNNB1	P31751	AKT2	S129	V136A	136	Missense	distal	7	no	22.753	22.843	EPSD	TCGA;COSMIC	19.022	Up-regulation
AGC_Akt_AKT2_ST	P35222	CTNNB1	P31751	AKT2	S129	Q123H	123	Missense	distal	-6	no	22.753	23.047	EPSD	TCGA;COSMIC	19.022	Up-regulation
AGC_Akt_AKT2_ST	P35222	CTNNB1	P31751	AKT2	S129	R124C	124	Missense	distal	-5	no	22.753	-1.069	EPSD	TCGA	19.022	Loss
AGC_Akt_AKT2_ST	P35222	CTNNB1	P31751	AKT2	T217	R212H	212	Missense	distal	-5	no	22.100	10.225	EPSD	TCGA;CCLE	19.022	Loss
AGC_Akt_AKT2_ST	P35222	CTNNB1	P31751	AKT2	T217	C213F	213	Missense	distal	-4	no	22.100	22.051	EPSD	TCGA;COSMIC	19.022	Down-regulation
AGC_Akt_AKT2_ST	P35222	CTNNB1	P31751	AKT2	T217	A215T	215	Missense	proximal	-2	no	22.100	19.839	EPSD	TCGA;COSMIC	19.022	Down-regulation
AGC_Akt_AKT2_ST	P35222	CTNNB1	P31751	AKT2	T332	E334A	334	Missense	proximal	2	no	18.835	19.718	EPSD	TCGA;COSMIC	19.022	Gain
AGC_Akt_AKT2_ST	P35222	CTNNB1	P31751	AKT2	T332	K335T	335	Missense	distal	3	no	18.835	19.950	EPSD	TCGA;COSMIC	19.022	Gain
AGC_Akt_AKT2_ST	P35222	CTNNB1	P31751	AKT2	T332	K335I	335	Missense	distal	3	no	18.835	20.209	EPSD	TCGA;COSMIC	19.022	Gain
AGC_Akt_AKT2_ST	P35222	CTNNB1	P31751	AKT2	T332	Y333F	333	Missense	proximal	1	no	18.835	20.451	EPSD	TCGA;COSMIC	19.022	Gain
AGC_Akt_AKT2_ST	P35222	CTNNB1	P31751	AKT2	T472	R469H	469	Missense	distal	-3	no	26.305	6.497	EPSD	TCGA;COSMIC	19.022	Loss
AGC_Akt_AKT2_ST	P35222	CTNNB1	P31751	AKT2	T472	R474Q	474	Missense	proximal	2	no	26.305	26.825	EPSD	TCGA;GDSC;CCLE	19.022	Up-regulation
AGC_Akt_AKT2_ST	P35222	CTNNB1	P31751	AKT2	S552	M553V	553	Missense	proximal	1	no	30.281	29.190	PhosphoSitePlus	TCGA;COSMIC	19.022	Down-regulation
AGC_Akt_AKT2_ST	Q9GZV1	ANKRD2	P31751	AKT2	S99	R94H	94	Missense	distal	-5	no	31.516	19.642	PhosphoSitePlus	TCGA;COSMIC	19.022	Down-regulation
AGC_Akt_AKT2_ST	Q9GZV1	ANKRD2	P31751	AKT2	S99	R96C	96	Missense	distal	-3	no	31.516	-2.493	PhosphoSitePlus	TCGA;COSMIC	19.022	Loss
AGC_Akt_AKT2_ST	Q86YS7	C2CD5	P31751	AKT2	S197	R192K	192	Missense	distal	-5	no	34.053	30.386	PhosphoSitePlus	TCGA;ICGC;COSMIC	19.022	Down-regulation
AGC_Akt_AKT2_ST	Q86YS7	C2CD5	P31751	AKT2	S262	M265I	265	Missense	distal	3	no	19.614	20.126	EPSD	TCGA;ICGC;COSMIC	19.022	Up-regulation
AGC_Akt_AKT2_ST	Q86YS7	C2CD5	P31751	AKT2	S262	E267K	267	Missense	distal	5	no	19.614	19.094	EPSD	TCGA;COSMIC	19.022	Down-regulation
AGC_Akt_AKT2_ST	Q86YS7	C2CD5	P31751	AKT2	S301	S297F	297	Missense	distal	-4	no	19.998	20.436	EPSD	TCGA;ICGC	19.022	Up-regulation
AGC_Akt_AKT2_ST	Q86YS7	C2CD5	P31751	AKT2	S305	L311F	311	Missense	distal	6	no	20.551	19.943	EPSD	TCGA;ICGC;COSMIC	19.022	Down-regulation
AGC_Akt_AKT2_ST	Q86YS7	C2CD5	P31751	AKT2	S341	E344G	344	Missense	distal	3	no	22.500	22.759	EPSD	TCGA;COSMIC	19.022	Up-regulation
AGC_Akt_AKT2_ST	Q86YS7	C2CD5	P31751	AKT2	T601	G605D	605	Missense	distal	4	no	20.186	20.346	EPSD	TCGA;COSMIC	19.022	Up-regulation
AGC_Akt_AKT2_ST	Q86YS7	C2CD5	P31751	AKT2	S863	S870F	870	Missense	distal	7	no	22.335	21.295	EPSD	TCGA;COSMIC	19.022	Down-regulation
AGC_Akt_AKT2_ST	Q7Z6J0	SH3RF1	P31751	AKT2	S125	G132R	132	Missense	distal	7	no	29.209	29.839	EPSD	TCGA;ICGC;COSMIC	19.022	Up-regulation
AGC_Akt_AKT2_ST	Q7Z6J0	SH3RF1	P31751	AKT2	S125	R122L	122	Missense	distal	-3	no	29.209	21.112	EPSD	TCGA;ICGC;COSMIC	19.022	Down-regulation
AGC_Akt_AKT2_ST	Q7Z6J0	SH3RF1	P31751	AKT2	S125	G132S	132	Missense	distal	7	no	29.209	29.731	EPSD	TCGA;ICGC;COSMIC	19.022	Up-regulation
AGC_Akt_AKT2_ST	Q7Z6J0	SH3RF1	P31751	AKT2	S125	R122Q	122	Missense	distal	-3	no	29.209	20.524	EPSD	TCGA;ICGC;COSMIC	19.022	Down-regulation
AGC_Akt_AKT2_ST	Q7Z6J0	SH3RF1	P31751	AKT2	S304	R302W	302	Missense	proximal	-2	no	27.123	21.950	PhosphoSitePlus	TCGA;ICGC;COSMIC;CCLE	19.022	Down-regulation
AGC_Akt_AKT2_ST	Q7Z6J0	SH3RF1	P31751	AKT2	S304	S307F	307	Missense	distal	3	no	27.123	28.336	PhosphoSitePlus	TCGA;ICGC;COSMIC	19.022	Up-regulation
AGC_Akt_AKT2_ST	Q7Z6J0	SH3RF1	P31751	AKT2	S334	I332V	332	Missense	proximal	-2	no	18.446	20.461	EPSD	TCGA;ICGC;COSMIC	19.022	Gain
AGC_Akt_AKT2_ST	Q7Z6J0	SH3RF1	P31751	AKT2	T509	V508M	508	Missense	proximal	-1	no	25.931	25.400	EPSD	TCGA;ICGC;COSMIC	19.022	Down-regulation
AGC_Akt_AKT2_ST	Q7Z6J0	SH3RF1	P31751	AKT2	T529	Q523H	523	Missense	distal	-6	no	19.448	19.743	EPSD	TCGA;ICGC;COSMIC	19.022	Up-regulation
AGC_Akt_AKT2_ST	Q7Z6J0	SH3RF1	P31751	AKT2	T567	H564R	564	Missense	distal	-3	no	3.399	23.208	EPSD	TCGA;ICGC;COSMIC	19.022	Gain
AGC_Akt_AKT2_ST	Q7Z6J0	SH3RF1	P31751	AKT2	T684	P678S	678	Missense	distal	-6	no	20.214	19.699	EPSD	TCGA	19.022	Down-regulation
AGC_Akt_AKT2_ST	Q7Z6J0	SH3RF1	P31751	AKT2	S692	S697P	697	Missense	distal	5	no	23.212	22.407	EPSD	TCGA;ICGC	19.022	Down-regulation
AGC_Akt_AKT2_ST	Q7Z6J0	SH3RF1	P31751	AKT2	S727	R730W	730	Missense	distal	3	no	18.805	20.428	EPSD	TCGA;ICGC;COSMIC	19.022	Gain
AGC_Akt_AKT2_ST	Q7Z6J0	SH3RF1	P31751	AKT2	S727	P732S	732	Missense	distal	5	no	18.805	19.610	EPSD	TCGA;ICGC;COSMIC	19.022	Gain
AGC_Akt_AKT2_ST	Q7Z6J0	SH3RF1	P31751	AKT2	S735	S739L	739	Missense	distal	4	no	27.962	28.169	EPSD	TCGA;ICGC;COSMIC	19.022	Up-regulation
AGC_Akt_AKT2_ST	Q7Z6J0	SH3RF1	P31751	AKT2	S735	K731T	731	Missense	distal	-4	no	27.962	28.027	EPSD	TCGA;ICGC;COSMIC	19.022	Up-regulation
AGC_Akt_AKT2_ST	Q7Z6J0	SH3RF1	P31751	AKT2	S735	R730W	730	Missense	distal	-5	no	27.962	16.678	EPSD	TCGA;ICGC;COSMIC	19.022	Loss
AGC_Akt_AKT2_ST	Q7Z6J0	SH3RF1	P31751	AKT2	S735	P732S	732	Missense	distal	-3	no	27.962	25.122	EPSD	TCGA;ICGC;COSMIC	19.022	Down-regulation
AGC_Akt_AKT2_ST	Q7Z6J0	SH3RF1	P31751	AKT2	S735	R733H	733	Missense	proximal	-2	no	27.962	25.064	EPSD	TCGA;ICGC	19.022	Down-regulation
AGC_Akt_AKT2_ST	Q7Z6J0	SH3RF1	P31751	AKT2	S800	P807S	807	Missense	distal	7	no	29.656	29.980	EPSD	TCGA;ICGC;COSMIC	19.022	Up-regulation
AGC_Akt_AKT2_ST	Q7Z6J0	SH3RF1	P31751	AKT2	S800	S801F	801	Missense	proximal	1	no	29.656	31.247	EPSD	TCGA;ICGC;COSMIC	19.022	Up-regulation
AGC_Akt_AKT2_ST	Q15118	PDK1	P31751	AKT2	T346	A349T	349	Missense	distal	3	no	28.433	28.481	PhosphoSitePlus	TCGA;ICGC;COSMIC;GDSC	19.022	Up-regulation
AGC_Akt_AKT2_ST	Q15118	PDK1	P31751	AKT2	T346	E345Q	345	Missense	proximal	-1	no	28.433	28.248	PhosphoSitePlus	TCGA;ICGC;COSMIC	19.022	Down-regulation
AGC_Akt_AKT2_ST	Q15118	PDK1	P31751	AKT2	T346	A353P	353	Missense	distal	7	no	28.433	27.873	PhosphoSitePlus	TCGA;ICGC;COSMIC	19.022	Down-regulation
AGC_Akt_AKT2_ST	Q15118	PDK1	P31751	AKT2	T346	R343H	343	Missense	distal	-3	no	28.433	8.624	PhosphoSitePlus	TCGA;ICGC;COSMIC;GDSC;CCLE	19.022	Loss
AGC_Akt_AKT2_ST	P04406	GAPDH	P31751	AKT2	T19	I14V	14	Missense	distal	-5	no	22.837	19.220	EPSD	TCGA;ICGC;COSMIC	19.022	Down-regulation
AGC_Akt_AKT2_ST	P04406	GAPDH	P31751	AKT2	T19	G15R	15	Missense	distal	-4	no	22.837	22.463	EPSD	TCGA;ICGC;COSMIC	19.022	Down-regulation
AGC_Akt_AKT2_ST	P04406	GAPDH	P31751	AKT2	T19	G15E	15	Missense	distal	-4	no	22.837	22.661	EPSD	TCGA;ICGC;COSMIC	19.022	Down-regulation
AGC_Akt_AKT2_ST	P04406	GAPDH	P31751	AKT2	T19	R16C	16	Missense	distal	-3	no	22.837	-11.172	EPSD	TCGA;ICGC;COSMIC	19.022	Loss
AGC_Akt_AKT2_ST	P04406	GAPDH	P31751	AKT2	S83	D89G	89	Missense	distal	6	no	25.675	26.574	EPSD	TCGA;COSMIC	19.022	Up-regulation
AGC_Akt_AKT2_ST	P04406	GAPDH	P31751	AKT2	S83	K84N	84	Missense	proximal	1	no	25.675	26.345	EPSD	TCGA	19.022	Up-regulation
AGC_Akt_AKT2_ST	P04406	GAPDH	P31751	AKT2	T211	T211A	211	Missense	central	0	yes	19.326	0.000	EPSD	TCGA;COSMIC	19.022	Loss
AGC_Akt_AKT2_ST	P04406	GAPDH	P31751	AKT2	T237	A232T	232	Missense	distal	-5	no	29.610	28.110	PhosphoSitePlus	TCGA;COSMIC	19.022	Down-regulation
AGC_Akt_AKT2_ST	P04406	GAPDH	P31751	AKT2	T237	A238S	238	Missense	proximal	1	no	29.610	29.461	PhosphoSitePlus	TCGA;COSMIC	19.022	Down-regulation
CMGC_DYRK_HIPK_HIPK3_ST	Q9UER7	DAXX	Q9H422	HIPK3	T162	P155S	155	Missense	distal	-7	no	0.456	1.425	EPSD	TCGA;ICGC;COSMIC	1.096	Gain
CMGC_DYRK_HIPK_HIPK3_ST	Q9UER7	DAXX	Q9H422	HIPK3	S178	E172K	172	Missense	distal	-6	no	4.314	4.350	EPSD	TCGA;ICGC;COSMIC;CCLE	1.096	Up-regulation
CMGC_DYRK_HIPK_HIPK3_ST	Q9UER7	DAXX	Q9H422	HIPK3	S178	S176C	176	Missense	proximal	-2	no	4.314	4.372	EPSD	TCGA;ICGC;COSMIC	1.096	Up-regulation
CMGC_DYRK_HIPK_HIPK3_ST	Q9UER7	DAXX	Q9H422	HIPK3	S178	R180M	180	Missense	proximal	2	no	4.314	4.316	EPSD	TCGA;ICGC	1.096	Up-regulation
CMGC_DYRK_HIPK_HIPK3_ST	Q9UER7	DAXX	Q9H422	HIPK3	S178	A175T	175	Missense	distal	-3	no	4.314	4.341	EPSD	TCGA;ICGC	1.096	Up-regulation
CMGC_DYRK_HIPK_HIPK3_ST	Q9UER7	DAXX	Q9H422	HIPK3	S184	R190C	190	Missense	distal	6	no	1.097	1.043	EPSD	TCGA;ICGC;COSMIC	1.096	Loss
CMGC_DYRK_HIPK_HIPK3_ST	Q9UER7	DAXX	Q9H422	HIPK3	S184	R180M	180	Missense	distal	-4	no	1.097	1.095	EPSD	TCGA;ICGC	1.096	Loss
CMGC_DYRK_HIPK_HIPK3_ST	Q9UER7	DAXX	Q9H422	HIPK3	S403	H404Y	404	Missense	proximal	1	no	1.099	1.053	EPSD	TCGA;ICGC;COSMIC	1.096	Loss
CMGC_DYRK_HIPK_HIPK3_ST	Q9UER7	DAXX	Q9H422	HIPK3	S403	S402F	402	Missense	proximal	-1	no	1.099	1.040	EPSD	TCGA;ICGC;COSMIC	1.096	Loss
CMGC_DYRK_HIPK_HIPK3_ST	Q9UER7	DAXX	Q9H422	HIPK3	S403	D407V	407	Missense	distal	4	no	1.099	1.087	EPSD	TCGA;ICGC;COSMIC	1.096	Loss
CMGC_DYRK_HIPK_HIPK3_ST	Q9UER7	DAXX	Q9H422	HIPK3	S403	E410D	410	Missense	distal	7	no	1.099	1.186	EPSD	TCGA;ICGC	1.096	Up-regulation
CMGC_DYRK_HIPK_HIPK3_ST	Q9UER7	DAXX	Q9H422	HIPK3	T408	H404Y	404	Missense	distal	-4	no	4.038	4.047	EPSD	TCGA;ICGC;COSMIC	1.096	Up-regulation
CMGC_DYRK_HIPK_HIPK3_ST	Q9UER7	DAXX	Q9H422	HIPK3	T408	L413F	413	Missense	distal	5	no	4.038	4.040	EPSD	TCGA;ICGC;COSMIC	1.096	Up-regulation
CMGC_DYRK_HIPK_HIPK3_ST	Q9UER7	DAXX	Q9H422	HIPK3	T408	S415F	415	Missense	distal	7	no	4.038	4.202	EPSD	TCGA;ICGC;COSMIC	1.096	Up-regulation
CMGC_DYRK_HIPK_HIPK3_ST	Q9UER7	DAXX	Q9H422	HIPK3	T408	S402F	402	Missense	distal	-6	no	4.038	4.009	EPSD	TCGA;ICGC;COSMIC	1.096	Down-regulation
CMGC_DYRK_HIPK_HIPK3_ST	Q9UER7	DAXX	Q9H422	HIPK3	T408	D407V	407	Missense	proximal	-1	no	4.038	4.031	EPSD	TCGA;ICGC;COSMIC	1.096	Down-regulation
CMGC_DYRK_HIPK_HIPK3_ST	Q9UER7	DAXX	Q9H422	HIPK3	T408	E410D	410	Missense	proximal	2	no	4.038	4.036	EPSD	TCGA;ICGC	1.096	Down-regulation
CMGC_DYRK_HIPK_HIPK3_ST	Q9UER7	DAXX	Q9H422	HIPK3	S412	L413F	413	Missense	proximal	1	no	0.847	1.371	EPSD	TCGA;ICGC;COSMIC	1.096	Gain
CMGC_DYRK_HIPK_HIPK3_ST	Q9UER7	DAXX	Q9H422	HIPK3	S495	S495N	495	Missense	central	0	yes	4.280	0.000	EPSD	TCGA;ICGC	1.096	Loss
CMGC_DYRK_HIPK_HIPK3_ST	Q9UER7	DAXX	Q9H422	HIPK3	S561	L566F	566	Missense	distal	5	no	4.001	4.002	EPSD	TCGA;ICGC;COSMIC	1.096	Up-regulation
CMGC_DYRK_HIPK_HIPK3_ST	Q9UER7	DAXX	Q9H422	HIPK3	S561	P562L	562	Missense	proximal	1	no	4.001	-0.421	EPSD	TCGA;ICGC;COSMIC	1.096	Loss
CMGC_DYRK_HIPK_HIPK3_ST	Q9UER7	DAXX	Q9H422	HIPK3	S618	S612T	612	Missense	distal	-6	no	3.837	3.804	EPSD	TCGA;ICGC	1.096	Down-regulation
CMGC_DYRK_HIPK_HIPK3_ST	Q9UER7	DAXX	Q9H422	HIPK3	S668	P667L	667	Missense	proximal	-1	no	4.666	4.695	PhosphoSitePlus	TCGA;ICGC;COSMIC	1.096	Up-regulation
CMGC_DYRK_HIPK_HIPK3_ST	Q9UER7	DAXX	Q9H422	HIPK3	S668	C664F	664	Missense	distal	-4	no	4.666	4.678	PhosphoSitePlus	TCGA;ICGC;COSMIC	1.096	Up-regulation
CMGC_DYRK_HIPK_HIPK3_ST	Q9UER7	DAXX	Q9H422	HIPK3	S668	S671F	671	Missense	distal	3	no	4.666	4.606	PhosphoSitePlus	TCGA;ICGC;COSMIC	1.096	Down-regulation
CMGC_DYRK_HIPK_HIPK3_ST	Q9UER7	DAXX	Q9H422	HIPK3	S668	K662N	662	Missense	distal	-6	no	4.666	4.646	PhosphoSitePlus	TCGA;ICGC;COSMIC	1.096	Down-regulation
CMGC_DYRK_HIPK_HIPK3_ST	Q9UER7	DAXX	Q9H422	HIPK3	S671	P667L	667	Missense	distal	-4	no	3.219	3.250	EPSD	TCGA;ICGC;COSMIC	1.096	Up-regulation
CMGC_DYRK_HIPK_HIPK3_ST	Q9UER7	DAXX	Q9H422	HIPK3	S671	C664F	664	Missense	distal	-7	no	3.219	3.117	EPSD	TCGA;ICGC;COSMIC	1.096	Down-regulation
CMGC_DYRK_HIPK_HIPK3_ST	Q9UER7	DAXX	Q9H422	HIPK3	S671	S671F	671	Missense	central	0	yes	3.219	0.000	EPSD	TCGA;ICGC;COSMIC	1.096	Loss
CMGC_DYRK_HIPK_HIPK3_ST	Q9UER7	DAXX	Q9H422	HIPK3	S688	S682C	682	Missense	distal	-6	no	4.728	4.712	EPSD	TCGA;ICGC;COSMIC	1.096	Down-regulation
CMGC_DYRK_HIPK_HIPK3_ST	Q9UER7	DAXX	Q9H422	HIPK3	S688	R685M	685	Missense	distal	-3	no	4.728	4.698	EPSD	TCGA;ICGC	1.096	Down-regulation
CMGC_DYRK_HIPK_HIPK3_ST	Q9UER7	DAXX	Q9H422	HIPK3	S702	P701L	701	Missense	proximal	-1	no	4.960	4.988	EPSD	TCGA;ICGC;COSMIC	1.096	Up-regulation
CMGC_DYRK_HIPK_HIPK3_ST	Q9UER7	DAXX	Q9H422	HIPK3	S702	S702F	702	Missense	central	0	yes	4.960	0.000	EPSD	TCGA;ICGC;COSMIC	1.096	Loss
CMGC_DYRK_HIPK_HIPK3_ST	Q9UER7	DAXX	Q9H422	HIPK3	T709	S702F	702	Missense	distal	-7	no	4.852	4.118	EPSD	TCGA;ICGC;COSMIC	1.096	Down-regulation
AGC_PKC_PKCa_PRKCB_ST	Q96PH1	NOX5	P05771	PRKCB	S521	R517M	517	Missense	distal	-4	no	2.239	2.551	EPSD	TCGA;ICGC	0.942	Up-regulation
AGC_PKC_PKCa_PRKCB_ST	Q96PH1	NOX5	P05771	PRKCB	S536	G531A	531	Missense	distal	-5	no	4.376	4.425	EPSD	TCGA;ICGC;COSMIC	0.942	Up-regulation
AGC_PKC_PKCa_PRKCB_ST	Q96PH1	NOX5	P05771	PRKCB	S536	R542T	542	Missense	distal	6	no	4.376	3.605	EPSD	TCGA;COSMIC	0.942	Down-regulation
AGC_PKC_PKCa_PRKCB_ST	Q96PH1	NOX5	P05771	PRKCB	S536	R530C	530	Missense	distal	-6	no	4.376	4.021	EPSD	TCGA;ICGC;COSMIC	0.942	Down-regulation
AGC_PKC_PKCa_PRKCB_ST	Q96PH1	NOX5	P05771	PRKCB	S536	G529C	529	Missense	distal	-7	no	4.376	4.240	EPSD	TCGA;COSMIC	0.942	Down-regulation
AGC_PKC_PKCa_PRKCB_ST	Q96PH1	NOX5	P05771	PRKCB	S536	K543N	543	Missense	distal	7	no	4.376	4.418	EPSD	TCGA;ICGC;COSMIC	0.942	Up-regulation
AGC_PKC_PKCa_PRKCB_ST	Q96PH1	NOX5	P05771	PRKCB	T540	R542T	542	Missense	proximal	2	no	5.403	0.760	EPSD	TCGA;COSMIC	0.942	Loss
AGC_PKC_PKCa_PRKCB_ST	Q96PH1	NOX5	P05771	PRKCB	T540	K543N	543	Missense	distal	3	no	5.403	5.257	EPSD	TCGA;ICGC;COSMIC	0.942	Down-regulation
AGC_PKC_PKCa_PRKCB_ST	Q96PH1	NOX5	P05771	PRKCB	S544	R542T	542	Missense	proximal	-2	no	7.783	6.395	EPSD	TCGA;COSMIC	0.942	Down-regulation
AGC_PKC_PKCa_PRKCB_ST	Q96PH1	NOX5	P05771	PRKCB	S544	S551Y	551	Missense	distal	7	no	7.783	7.726	EPSD	TCGA;COSMIC	0.942	Down-regulation
AGC_PKC_PKCa_PRKCB_ST	Q96PH1	NOX5	P05771	PRKCB	S544	G550S	550	Missense	distal	6	no	7.783	8.240	EPSD	TCGA;COSMIC	0.942	Up-regulation
AGC_PKC_PKCa_PRKCB_ST	Q96PH1	NOX5	P05771	PRKCB	S544	K543N	543	Missense	proximal	-1	no	7.783	7.499	EPSD	TCGA;ICGC;COSMIC	0.942	Down-regulation
AGC_PKC_PKCa_PRKCB_ST	Q96PH1	NOX5	P05771	PRKCB	S705	T707M	707	Missense	proximal	2	no	4.320	2.202	EPSD	TCGA;COSMIC	0.942	Down-regulation
AGC_PKC_PKCa_PRKCB_ST	Q96PH1	NOX5	P05771	PRKCB	S705	R712C	712	Missense	distal	7	no	4.320	4.517	EPSD	TCGA;COSMIC	0.942	Up-regulation
AGC_PKC_PKCa_PRKCB_ST	P04083	ANXA1	P05771	PRKCB	T24	S27L	27	Missense	distal	3	no	1.942	1.622	EPSD	TCGA;ICGC;COSMIC	0.942	Down-regulation
AGC_PKC_PKCa_PRKCB_ST	P04083	ANXA1	P05771	PRKCB	T24	E17K	17	Missense	distal	-7	no	1.942	1.738	EPSD	TCGA;ICGC;COSMIC	0.942	Down-regulation
AGC_PKC_PKCa_PRKCB_ST	P04083	ANXA1	P05771	PRKCB	T24	K29N	29	Missense	distal	5	no	1.942	1.569	EPSD	TCGA;ICGC;COSMIC	0.942	Down-regulation
AGC_PKC_PKCa_PRKCB_ST	P04083	ANXA1	P05771	PRKCB	S27	P32A	32	Missense	distal	5	no	3.204	3.389	EPSD	TCGA;ICGC;COSMIC	0.942	Up-regulation
AGC_PKC_PKCa_PRKCB_ST	P04083	ANXA1	P05771	PRKCB	S27	S27L	27	Missense	central	0	yes	3.204	0.000	EPSD	TCGA;ICGC;COSMIC	0.942	Loss
AGC_PKC_PKCa_PRKCB_ST	P04083	ANXA1	P05771	PRKCB	S27	K29N	29	Missense	proximal	2	no	3.204	-0.451	EPSD	TCGA;ICGC;COSMIC	0.942	Loss
AGC_PKC_PKCa_PRKCB_ST	P04083	ANXA1	P05771	PRKCB	S28	P32A	32	Missense	distal	4	no	1.132	0.527	PhosphoSitePlus	TCGA;ICGC;COSMIC	0.942	Loss
AGC_PKC_PKCa_PRKCB_ST	P04083	ANXA1	P05771	PRKCB	S28	S27L	27	Missense	proximal	-1	no	1.132	1.124	PhosphoSitePlus	TCGA;ICGC;COSMIC	0.942	Down-regulation
AGC_PKC_PKCa_PRKCB_ST	P04083	ANXA1	P05771	PRKCB	S28	A35V	35	Missense	distal	7	no	1.132	1.077	PhosphoSitePlus	TCGA;ICGC;COSMIC	0.942	Down-regulation
AGC_PKC_PKCa_PRKCB_ST	P04083	ANXA1	P05771	PRKCB	S28	K29N	29	Missense	proximal	1	no	1.132	-1.687	PhosphoSitePlus	TCGA;ICGC;COSMIC	0.942	Loss
AGC_PKC_PKCa_PRKCB_ST	P10636	MAPT	P05771	PRKCB	S171	R168H	168	Missense	distal	-3	no	2.924	-0.062	EPSD	TCGA;ICGC;COSMIC	0.942	Loss
AGC_PKC_PKCa_PRKCB_ST	P10636	MAPT	P05771	PRKCB	S171	R168C	168	Missense	distal	-3	no	2.924	-0.975	EPSD	TCGA;ICGC;COSMIC	0.942	Loss
AGC_PKC_PKCa_PRKCB_ST	P10636	MAPT	P05771	PRKCB	S214	P212L	212	Missense	proximal	-2	no	1.656	0.968	EPSD	TCGA;ICGC;COSMIC	0.942	Down-regulation
AGC_PKC_PKCa_PRKCB_ST	P10636	MAPT	P05771	PRKCB	S214	E220K	220	Missense	distal	6	no	1.656	2.152	EPSD	TCGA;ICGC;COSMIC	0.942	Up-regulation
AGC_PKC_PKCa_PRKCB_ST	P10636	MAPT	P05771	PRKCB	S355	E348V	348	Missense	distal	-7	no	3.476	3.593	EPSD	TCGA;ICGC;COSMIC	0.942	Up-regulation
AGC_PKC_PKCa_PRKCB_ST	P10636	MAPT	P05771	PRKCB	S355	D350G	350	Missense	distal	-5	no	3.476	3.360	EPSD	TCGA;ICGC;COSMIC	0.942	Down-regulation
AGC_PKC_PKCa_PRKCB_ST	P10636	MAPT	P05771	PRKCB	S369	Q373R	373	Missense	distal	4	no	3.530	4.150	EPSD	TCGA;ICGC;COSMIC	0.942	Up-regulation
AGC_PKC_PKCa_PRKCB_ST	P10636	MAPT	P05771	PRKCB	S369	K366E	366	Missense	distal	-3	no	3.530	0.195	EPSD	TCGA;ICGC;COSMIC	0.942	Loss
AGC_PKC_PKCa_PRKCB_ST	P10636	MAPT	P05771	PRKCB	S438	P436T	436	Missense	proximal	-2	no	1.209	1.654	EPSD	TCGA;ICGC;COSMIC	0.942	Up-regulation
AGC_PKC_PKCa_PRKCB_ST	P10636	MAPT	P05771	PRKCB	S438	P436L	436	Missense	proximal	-2	no	1.209	0.521	EPSD	TCGA;ICGC;COSMIC	0.942	Loss
AGC_PKC_PKCa_PRKCB_ST	P10636	MAPT	P05771	PRKCB	S438	K440E	440	Missense	proximal	2	no	1.209	-4.205	EPSD	TCGA;ICGC;COSMIC	0.942	Loss
AGC_PKC_PKCa_PRKCB_ST	P10636	MAPT	P05771	PRKCB	S438	S443F	443	Missense	distal	5	no	1.209	1.165	EPSD	TCGA;ICGC;COSMIC	0.942	Down-regulation
AGC_PKC_PKCa_PRKCB_ST	P10636	MAPT	P05771	PRKCB	S438	V431L	431	Missense	distal	-7	no	1.209	1.197	EPSD	TCGA;ICGC;COSMIC	0.942	Down-regulation
AGC_PKC_PKCa_PRKCB_ST	P10636	MAPT	P05771	PRKCB	S438	S444F	444	Missense	distal	6	no	1.209	0.792	EPSD	TCGA;ICGC	0.942	Loss
AGC_PKC_PKCa_PRKCB_ST	P10636	MAPT	P05771	PRKCB	T470	R472Q	472	Missense	proximal	2	no	3.997	-2.552	EPSD	TCGA	0.942	Loss
AGC_PKC_PKCa_PRKCB_ST	P10636	MAPT	P05771	PRKCB	T470	R472W	472	Missense	proximal	2	no	3.997	-5.517	EPSD	TCGA;COSMIC	0.942	Loss
AGC_PKC_PKCa_PRKCB_ST	P05107	ITGB2	P05771	PRKCB	T118	A112S	112	Missense	distal	-6	no	4.279	4.356	EPSD	TCGA;ICGC;COSMIC	0.942	Up-regulation
AGC_PKC_PKCa_PRKCB_ST	P05107	ITGB2	P05771	PRKCB	T118	R121Q	121	Missense	distal	3	no	4.279	3.714	EPSD	TCGA;ICGC;COSMIC	0.942	Down-regulation
AGC_PKC_PKCa_PRKCB_ST	P05107	ITGB2	P05771	PRKCB	T118	R121W	121	Missense	distal	3	no	4.279	2.927	EPSD	TCGA;ICGC;COSMIC	0.942	Down-regulation
AGC_PKC_PKCa_PRKCB_ST	P05107	ITGB2	P05771	PRKCB	T118	R120W	120	Missense	proximal	2	no	4.279	-5.235	EPSD	TCGA;ICGC	0.942	Loss
AGC_PKC_PKCa_PRKCB_ST	P05107	ITGB2	P05771	PRKCB	S496	D500G	500	Missense	distal	4	no	3.467	3.054	EPSD	TCGA;ICGC;COSMIC	0.942	Down-regulation
AGC_PKC_PKCa_PRKCB_ST	P05107	ITGB2	P05771	PRKCB	S496	R498Q	498	Missense	proximal	2	no	3.467	-3.081	EPSD	TCGA;ICGC;COSMIC	0.942	Loss
AGC_PKC_PKCa_PRKCB_ST	P05107	ITGB2	P05771	PRKCB	S496	G495R	495	Missense	proximal	-1	no	3.467	4.000	EPSD	TCGA;ICGC;COSMIC	0.942	Up-regulation
AGC_PKC_PKCa_PRKCB_ST	P05107	ITGB2	P05771	PRKCB	S591	R587C	587	Missense	distal	-4	no	5.199	5.705	EPSD	TCGA;ICGC;COSMIC	0.942	Up-regulation
AGC_PKC_PKCa_PRKCB_ST	P05107	ITGB2	P05771	PRKCB	S591	R586Q	586	Missense	distal	-5	no	5.199	5.182	EPSD	TCGA;ICGC;COSMIC	0.942	Down-regulation
AGC_PKC_PKCa_PRKCB_ST	P05107	ITGB2	P05771	PRKCB	S591	G594D	594	Missense	distal	3	no	5.199	5.569	EPSD	TCGA;ICGC;COSMIC	0.942	Up-regulation
AGC_PKC_PKCa_PRKCB_ST	P05107	ITGB2	P05771	PRKCB	S591	R597H	597	Missense	distal	6	no	5.199	4.439	EPSD	TCGA;ICGC;COSMIC	0.942	Down-regulation
AGC_PKC_PKCa_PRKCB_ST	P05107	ITGB2	P05771	PRKCB	S745	L743R	743	Missense	proximal	-2	no	0.240	2.760	PhosphoSitePlus;EPSD	TCGA;ICGC;COSMIC	0.942	Gain
AGC_PKC_PKCa_PRKCB_ST	P05107	ITGB2	P05771	PRKCB	S745	W747L	747	Missense	proximal	2	no	0.240	3.122	PhosphoSitePlus;EPSD	TCGA;ICGC;COSMIC	0.942	Gain
AGC_PKC_PKCa_PRKCB_ST	P28799	GRN	P05771	PRKCB	S435	A431V	431	Missense	distal	-4	no	4.263	4.120	EPSD	TCGA;ICGC;COSMIC	0.942	Down-regulation
AGC_PKC_PKCa_PRKCB_ST	P28799	GRN	P05771	PRKCB	S435	A434D	434	Missense	proximal	-1	no	4.263	4.432	EPSD	TCGA;ICGC;COSMIC	0.942	Up-regulation
AGC_PKC_PKCa_PRKCB_ST	P05771	PRKCB	P05771	PRKCB	S16	A21S	21	Missense	distal	5	no	2.322	2.193	EPSD	TCGA;ICGC	0.942	Down-regulation
AGC_PKC_PKCa_PRKCB_ST	P05771	PRKCB	P05771	PRKCB	S16	E14K	14	Missense	proximal	-2	no	2.322	3.766	EPSD	TCGA	0.942	Up-regulation
AGC_PKC_PKCa_PRKCB_ST	P05771	PRKCB	P05771	PRKCB	S16	F20S	20	Missense	distal	4	no	2.322	2.471	EPSD	TCGA;ICGC;COSMIC	0.942	Up-regulation
AGC_PKC_PKCa_PRKCB_ST	P05771	PRKCB	P05771	PRKCB	S16	R19L	19	Missense	distal	3	no	2.322	1.236	EPSD	TCGA;ICGC;COSMIC	0.942	Down-regulation
AGC_PKC_PKCa_PRKCB_ST	P05771	PRKCB	P05771	PRKCB	S16	R19C	19	Missense	distal	3	no	2.322	1.469	EPSD	TCGA;ICGC;COSMIC	0.942	Down-regulation
AGC_PKC_PKCa_PRKCB_ST	P05771	PRKCB	P05771	PRKCB	S16	V18M	18	Missense	proximal	2	no	2.322	0.863	EPSD	TCGA;ICGC;COSMIC	0.942	Loss
AGC_PKC_PKCa_PRKCB_ST	P05771	PRKCB	P05771	PRKCB	S16	A21T	21	Missense	distal	5	no	2.322	2.260	EPSD	TCGA;ICGC;COSMIC	0.942	Down-regulation
AGC_PKC_PKCa_PRKCB_ST	P05771	PRKCB	P05771	PRKCB	T17	A21S	21	Missense	distal	4	no	3.564	4.034	EPSD	TCGA;ICGC	0.942	Up-regulation
AGC_PKC_PKCa_PRKCB_ST	P05771	PRKCB	P05771	PRKCB	T17	E14K	14	Missense	distal	-3	no	3.564	6.899	EPSD	TCGA	0.942	Up-regulation
AGC_PKC_PKCa_PRKCB_ST	P05771	PRKCB	P05771	PRKCB	T17	F20S	20	Missense	distal	3	no	3.564	3.826	EPSD	TCGA;ICGC;COSMIC	0.942	Up-regulation
AGC_PKC_PKCa_PRKCB_ST	P05771	PRKCB	P05771	PRKCB	T17	R19L	19	Missense	proximal	2	no	3.564	-3.068	EPSD	TCGA;ICGC;COSMIC	0.942	Loss
AGC_PKC_PKCa_PRKCB_ST	P05771	PRKCB	P05771	PRKCB	T17	R19C	19	Missense	proximal	2	no	3.564	-0.929	EPSD	TCGA;ICGC;COSMIC	0.942	Loss
AGC_PKC_PKCa_PRKCB_ST	P05771	PRKCB	P05771	PRKCB	T17	V18M	18	Missense	proximal	1	no	3.564	2.841	EPSD	TCGA;ICGC;COSMIC	0.942	Down-regulation
AGC_PKC_PKCa_PRKCB_ST	P05771	PRKCB	P05771	PRKCB	T17	A21T	21	Missense	distal	4	no	3.564	4.006	EPSD	TCGA;ICGC;COSMIC	0.942	Up-regulation
AGC_PKC_PKCa_PRKCB_ST	P05771	PRKCB	P05771	PRKCB	T40	A41T	41	Missense	proximal	1	no	3.397	2.951	EPSD	TCGA;ICGC;COSMIC	0.942	Down-regulation
AGC_PKC_PKCa_PRKCB_ST	P05771	PRKCB	P05771	PRKCB	T40	R42H	42	Missense	proximal	2	no	3.397	-2.965	EPSD	TCGA;ICGC;COSMIC	0.942	Loss
AGC_PKC_PKCa_PRKCB_ST	P05771	PRKCB	P05771	PRKCB	T48	A41T	41	Missense	distal	-7	no	2.065	2.036	EPSD	TCGA;ICGC;COSMIC	0.942	Down-regulation
AGC_PKC_PKCa_PRKCB_ST	P05771	PRKCB	P05771	PRKCB	T48	S51R	51	Missense	distal	3	no	2.065	2.830	EPSD	TCGA;ICGC;COSMIC	0.942	Up-regulation
AGC_PKC_PKCa_PRKCB_ST	P05771	PRKCB	P05771	PRKCB	T48	D55N	55	Missense	distal	7	no	2.065	2.144	EPSD	TCGA;ICGC;COSMIC	0.942	Up-regulation
AGC_PKC_PKCa_PRKCB_ST	P05771	PRKCB	P05771	PRKCB	T48	C53G	53	Missense	distal	5	no	2.065	2.078	EPSD	TCGA;ICGC;COSMIC	0.942	Up-regulation
AGC_PKC_PKCa_PRKCB_ST	P05771	PRKCB	P05771	PRKCB	T48	R42H	42	Missense	distal	-6	no	2.065	1.819	EPSD	TCGA;ICGC;COSMIC	0.942	Down-regulation
AGC_PKC_PKCa_PRKCB_ST	P05771	PRKCB	P05771	PRKCB	S110	H107R	107	Missense	distal	-3	no	-1.227	1.760	EPSD	TCGA;ICGC;COSMIC	0.942	Gain
AGC_PKC_PKCa_PRKCB_ST	P05771	PRKCB	P05771	PRKCB	S111	H107R	107	Missense	distal	-4	no	2.681	2.375	EPSD	TCGA;ICGC;COSMIC	0.942	Down-regulation
AGC_PKC_PKCa_PRKCB_ST	P05771	PRKCB	P05771	PRKCB	S111	C115F	115	Missense	distal	4	no	2.681	2.652	EPSD	TCGA;ICGC;COSMIC;GDSC;CCLE	0.942	Down-regulation
AGC_PKC_PKCa_PRKCB_ST	P05771	PRKCB	P05771	PRKCB	S111	P112L	112	Missense	proximal	1	no	2.681	3.817	EPSD	TCGA;ICGC;COSMIC	0.942	Up-regulation
AGC_PKC_PKCa_PRKCB_ST	P05771	PRKCB	P05771	PRKCB	T314	K309N	309	Missense	distal	-5	no	1.587	1.420	EPSD	TCGA;ICGC;COSMIC	0.942	Down-regulation
AGC_PKC_PKCa_PRKCB_ST	P05771	PRKCB	P05771	PRKCB	T314	T314A	314	Missense	central	0	yes	1.587	0.000	EPSD	TCGA;ICGC;COSMIC	0.942	Loss
AGC_PKC_PKCa_PRKCB_ST	P05771	PRKCB	P05771	PRKCB	T314	K315N	315	Missense	proximal	1	no	1.587	-1.232	EPSD	TCGA;ICGC;COSMIC	0.942	Loss
AGC_PKC_PKCa_PRKCB_ST	P05771	PRKCB	P05771	PRKCB	T314	T321M	321	Missense	distal	7	no	1.587	1.619	EPSD	TCGA;ICGC;COSMIC	0.942	Up-regulation
AGC_PKC_PKCa_PRKCB_ST	P05771	PRKCB	P05771	PRKCB	T500	D494N	494	Missense	distal	-6	no	2.613	2.679	EPSD	TCGA;ICGC;COSMIC	0.942	Up-regulation
AGC_PKC_PKCa_PRKCB_ST	P05771	PRKCB	P05771	PRKCB	T500	T498I	498	Missense	proximal	-2	no	2.613	2.450	EPSD	TCGA;ICGC;COSMIC	0.942	Down-regulation
AGC_PKC_PKCa_PRKCB_ST	P05771	PRKCB	P05771	PRKCB	T500	T498A	498	Missense	proximal	-2	no	2.613	2.208	EPSD	TCGA;ICGC;COSMIC	0.942	Down-regulation
AGC_PKC_PKCa_PRKCB_ST	P05771	PRKCB	P05771	PRKCB	T500	F501L	501	Missense	proximal	1	no	2.613	2.113	EPSD	TCGA;ICGC;COSMIC	0.942	Down-regulation
AGC_PKC_PKCa_PRKCB_ST	P05771	PRKCB	P05771	PRKCB	S565	A568D	568	Missense	distal	3	no	0.626	0.946	EPSD	TCGA;ICGC;COSMIC	0.942	Gain
AGC_PKC_PKCa_PRKCB_ST	P05771	PRKCB	P05771	PRKCB	S565	E567K	567	Missense	proximal	2	no	0.626	6.039	EPSD	TCGA;ICGC;COSMIC;CCLE	0.942	Gain
AGC_PKC_PKCa_PRKCB_ST	P29353	SHC1	P05771	PRKCB	S17	L18V	18	Missense	proximal	1	no	4.030	3.677	EPSD	TCGA;COSMIC	0.942	Down-regulation
AGC_PKC_PKCa_PRKCB_ST	P29353	SHC1	P05771	PRKCB	S17	R14W	14	Missense	distal	-3	no	4.030	-1.462	EPSD	TCGA;ICGC;COSMIC	0.942	Loss
AGC_PKC_PKCa_PRKCB_ST	P29353	SHC1	P05771	PRKCB	S139	R146Q	146	Missense	distal	7	no	3.625	3.700	EPSD;PhosphoSitePlus	TCGA;COSMIC	0.942	Up-regulation
AGC_PKC_PKCa_PRKCB_ST	P29353	SHC1	P05771	PRKCB	S139	H137L	137	Missense	proximal	-2	no	3.625	3.120	EPSD;PhosphoSitePlus	TCGA;COSMIC	0.942	Down-regulation
AGC_PKC_PKCa_PRKCB_ST	P29353	SHC1	P05771	PRKCB	T206	T206P	206	Missense	central	0	yes	8.391	0.000	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	0.942	Loss
AGC_PKC_PKCa_PRKCB_ST	P29353	SHC1	P05771	PRKCB	T206	A205V	205	Missense	proximal	-1	no	8.391	8.495	EPSD;PhosphoSitePlus	TCGA;COSMIC	0.942	Up-regulation
AGC_PKC_PKCa_PRKCB_ST	P29353	SHC1	P05771	PRKCB	S213	T206P	206	Missense	distal	-7	no	4.082	4.265	PhosphoSitePlus;EPSD	TCGA;ICGC;COSMIC	0.942	Up-regulation
AGC_PKC_PKCa_PRKCB_ST	Q03721	KCNC4	P05771	PRKCB	S21	E27Q	27	Missense	distal	6	no	4.869	4.409	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	0.942	Down-regulation
AGC_PKC_PKCa_PRKCB_ST	Q03721	KCNC4	P05771	PRKCB	S21	E28V	28	Missense	distal	7	no	4.869	4.969	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	0.942	Up-regulation
AGC_PKC_PKCa_PRKCB_ST	Q03721	KCNC4	P05771	PRKCB	T49	G44S	44	Missense	distal	-5	no	4.661	4.668	EPSD	TCGA;ICGC;COSMIC	0.942	Up-regulation
AGC_PKC_PKCa_PRKCB_ST	Q03721	KCNC4	P05771	PRKCB	T49	S52N	52	Missense	distal	3	no	4.661	4.824	EPSD	TCGA;ICGC;COSMIC	0.942	Up-regulation
AGC_PKC_PKCa_PRKCB_ST	Q03721	KCNC4	P05771	PRKCB	T49	E48D	48	Missense	proximal	-1	no	4.661	4.575	EPSD	TCGA;ICGC;COSMIC	0.942	Down-regulation
AGC_PKC_PKCa_PRKCB_ST	Q03721	KCNC4	P05771	PRKCB	T49	R46Q	46	Missense	distal	-3	no	4.661	1.463	EPSD	TCGA;ICGC;COSMIC;CCLE	0.942	Down-regulation
AGC_PKC_PKCa_PRKCB_ST	Q03721	KCNC4	P05771	PRKCB	S514	S510F	510	Missense	distal	-4	no	3.036	3.014	EPSD	TCGA;ICGC;COSMIC	0.942	Down-regulation
AGC_PKC_PKCa_PRKCB_ST	Q03721	KCNC4	P05771	PRKCB	T578	A573T	573	Missense	distal	-5	no	7.188	7.197	EPSD	TCGA;ICGC;COSMIC	0.942	Up-regulation
AGC_PKC_PKCa_PRKCB_ST	Q03721	KCNC4	P05771	PRKCB	T578	R575L	575	Missense	distal	-3	no	7.188	3.032	EPSD	TCGA;ICGC;COSMIC	0.942	Down-regulation
AGC_PKC_PKCa_PRKCB_ST	Q03721	KCNC4	P05771	PRKCB	T578	R572Q	572	Missense	distal	-6	no	7.188	7.084	EPSD	TCGA;ICGC;COSMIC	0.942	Down-regulation
AGC_PKC_PKCa_PRKCB_ST	Q03721	KCNC4	P05771	PRKCB	T578	R576C	576	Missense	proximal	-2	no	7.188	5.722	EPSD	TCGA;ICGC;COSMIC	0.942	Down-regulation
AGC_PKC_PKCa_PRKCB_ST	Q03721	KCNC4	P05771	PRKCB	T578	R576L	576	Missense	proximal	-2	no	7.188	4.668	EPSD	TCGA;ICGC;COSMIC	0.942	Down-regulation
AGC_PKC_PKCa_PRKCB_ST	P15336	ATF2	P05771	PRKCB	S100	E93Q	93	Missense	distal	-7	no	5.803	5.668	EPSD	TCGA;COSMIC	0.942	Down-regulation
AGC_PKC_PKCa_PRKCB_ST	P15336	ATF2	P05771	PRKCB	S146	E148K	148	Missense	proximal	2	no	-3.872	1.542	EPSD	TCGA;COSMIC	0.942	Gain
AGC_PKC_PKCa_PRKCB_ST	P15336	ATF2	P05771	PRKCB	S314	P312L	312	Missense	proximal	-2	no	1.491	0.804	EPSD	TCGA;COSMIC	0.942	Loss
AGC_PKC_PKCa_PRKCB_ST	P15336	ATF2	P05771	PRKCB	S314	S321F	321	Missense	distal	7	no	1.491	1.549	EPSD	TCGA;COSMIC	0.942	Up-regulation
AGC_PKC_PKCa_PRKCB_ST	P15336	ATF2	P05771	PRKCB	S314	E308Q	308	Missense	distal	-6	no	1.491	1.473	EPSD	TCGA;COSMIC	0.942	Down-regulation
AGC_PKC_PKCa_PRKCB_ST	P15336	ATF2	P05771	PRKCB	S314	S310F	310	Missense	distal	-4	no	1.491	1.470	EPSD	TCGA;COSMIC	0.942	Down-regulation
AGC_PKC_PKCa_PRKCB_ST	P15336	ATF2	P05771	PRKCB	S340	P334A	334	Missense	distal	-6	no	2.871	2.908	EPSD	TCGA;COSMIC	0.942	Up-regulation
AGC_PKC_PKCa_PRKCB_ST	P15336	ATF2	P05771	PRKCB	S340	T339A	339	Missense	proximal	-1	no	2.871	2.717	EPSD	TCGA;COSMIC	0.942	Down-regulation
AGC_PKC_PKCa_PRKCB_ST	P15336	ATF2	P05771	PRKCB	S455	S456L	456	Missense	proximal	1	no	-0.054	1.286	EPSD	TCGA;COSMIC	0.942	Gain
AGC_PKC_PKCa_PRKCB_ST	Q06124	PTPN11	P05771	PRKCB	S140	L136H	136	Missense	distal	-4	no	1.121	1.044	EPSD	TCGA;ICGC;COSMIC	0.942	Down-regulation
AGC_PKC_PKCa_PRKCB_ST	Q06124	PTPN11	P05771	PRKCB	S140	S142N	142	Missense	proximal	2	no	1.121	1.840	EPSD	TCGA;ICGC;COSMIC;GDSC;CCLE	0.942	Up-regulation
AGC_PKC_PKCa_PRKCB_ST	Q06124	PTPN11	P05771	PRKCB	S140	D146Y	146	Missense	distal	6	no	1.121	0.792	EPSD	TCGA;ICGC;COSMIC	0.942	Loss
AGC_PKC_PKCa_PRKCB_ST	Q06124	PTPN11	P05771	PRKCB	S160	D155N	155	Missense	distal	-5	no	0.985	0.919	EPSD	TCGA;ICGC;COSMIC	0.942	Loss
AGC_PKC_PKCa_PRKCB_ST	Q06124	PTPN11	P05771	PRKCB	S160	D156N	156	Missense	distal	-4	no	0.985	0.977	EPSD	TCGA;ICGC;COSMIC	0.942	Down-regulation
AGC_PKC_PKCa_PRKCB_ST	Q06124	PTPN11	P05771	PRKCB	S160	G163D	163	Missense	distal	3	no	0.985	1.355	EPSD	TCGA;ICGC;COSMIC	0.942	Up-regulation
AGC_PKC_PKCa_PRKCB_ST	Q06124	PTPN11	P05771	PRKCB	T397	E400K	400	Missense	distal	3	no	1.295	1.243	EPSD	TCGA;ICGC	0.942	Down-regulation
AGC_PKC_PKCa_PRKCB_ST	Q06124	PTPN11	P05771	PRKCB	S503	Q510L	510	Missense	distal	7	no	3.497	3.651	EPSD	TCGA;ICGC;COSMIC	0.942	Up-regulation
AGC_PKC_PKCa_PRKCB_ST	Q06124	PTPN11	P05771	PRKCB	S503	Q510H	510	Missense	distal	7	no	3.497	3.647	EPSD	TCGA;ICGC;COSMIC;GDSC;CCLE	0.942	Up-regulation
AGC_PKC_PKCa_PRKCB_ST	P49841	GSK3B	P05771	PRKCB	S13	Q19R	19	Missense	distal	6	no	1.665	2.470	EPSD	TCGA	0.942	Up-regulation
AGC_PKC_PKCa_PRKCB_ST	P49841	GSK3B	P05771	PRKCB	S25	A22S	22	Missense	distal	-3	no	0.733	1.264	EPSD	TCGA;ICGC	0.942	Gain
AGC_PKC_PKCa_PRKCB_ST	P49841	GSK3B	P05771	PRKCB	S35	G34S	34	Missense	proximal	-1	no	2.853	2.782	EPSD	TCGA;COSMIC	0.942	Down-regulation
AGC_PKC_PKCa_PRKCB_ST	P07355	ANXA2	P05771	PRKCB	S26	K28M	28	Missense	proximal	2	no	2.460	-2.678	PhosphoSitePlus	TCGA;COSMIC	0.942	Loss
AGC_PKC_PKCa_PRKCB_ST	Q16625	OCLN	P05771	PRKCB	S2	S3C	3	Missense	proximal	1	no	3.990	3.377	EPSD	TCGA;COSMIC	0.942	Down-regulation
AGC_PKC_PKCa_PRKCB_ST	Q16625	OCLN	P05771	PRKCB	S2	P9S	9	Missense	distal	7	no	3.990	3.897	EPSD	TCGA;ICGC;COSMIC	0.942	Down-regulation
AGC_PKC_PKCa_PRKCB_ST	Q16625	OCLN	P05771	PRKCB	S166	R170I	170	Missense	distal	4	no	1.749	0.873	EPSD	TCGA;ICGC	0.942	Loss
AGC_PKC_PKCa_PRKCB_ST	Q16625	OCLN	P05771	PRKCB	S166	V160A	160	Missense	distal	-6	no	1.749	1.683	EPSD	TCGA	0.942	Down-regulation
AGC_PKC_PKCa_PRKCB_ST	Q16625	OCLN	P05771	PRKCB	S378	G371D	371	Missense	distal	-7	no	6.257	5.987	EPSD	TCGA;ICGC	0.942	Down-regulation
AGC_PKC_PKCa_PRKCB_ST	Q16625	OCLN	P05771	PRKCB	S490	S495R	495	Missense	distal	5	no	1.946	2.353	PhosphoSitePlus	TCGA;ICGC	0.942	Up-regulation
AGC_PKC_PKCa_PRKCB_ST	Q9UBS0	RPS6KB2	P05771	PRKCB	S254	G256R	256	Missense	proximal	2	no	-5.375	3.359	EPSD	TCGA;ICGC;COSMIC	0.942	Gain
AGC_PKC_PKCa_PRKCB_ST	Q9UBS0	RPS6KB2	P05771	PRKCB	S410	S410L	410	Missense	central	0	yes	7.610	0.000	EPSD	TCGA;ICGC;COSMIC	0.942	Loss
AGC_PKC_PKCa_PRKCB_ST	Q9UBS0	RPS6KB2	P05771	PRKCB	S417	R419W	419	Missense	proximal	2	no	1.767	-7.746	EPSD	TCGA;ICGC;COSMIC	0.942	Loss
AGC_PKC_PKCa_PRKCB_ST	Q9UBS0	RPS6KB2	P05771	PRKCB	S417	S410L	410	Missense	distal	-7	no	1.767	1.761	EPSD	TCGA;ICGC;COSMIC	0.942	Down-regulation
AGC_PKC_PKCa_PRKCB_ST	P35548	MSX2	P05771	PRKCB	T141	R146H	146	Missense	distal	5	no	4.647	4.270	PhosphoSitePlus;EPSD	TCGA;ICGC;COSMIC	0.942	Down-regulation
AGC_PKC_PKCa_PRKCB_ST	P35548	MSX2	P05771	PRKCB	T141	P145L	145	Missense	distal	4	no	4.647	4.224	PhosphoSitePlus;EPSD	TCGA;ICGC;COSMIC	0.942	Down-regulation
AGC_PKC_PKCa_PRKCB_ST	P35548	MSX2	P05771	PRKCB	T141	R137M	137	Missense	distal	-4	no	4.647	4.959	PhosphoSitePlus;EPSD	TCGA;ICGC;COSMIC	0.942	Up-regulation
AGC_PKC_PKCa_PRKCB_ST	P35548	MSX2	P05771	PRKCB	T141	T147M	147	Missense	distal	6	no	4.647	4.482	PhosphoSitePlus;EPSD	TCGA;ICGC;COSMIC	0.942	Down-regulation
AGC_PKC_PKCa_PRKCB_ST	O15519	CFLAR	P05771	PRKCB	S193	P197H	197	Missense	distal	4	no	3.351	3.412	PhosphoSitePlus	TCGA;ICGC	0.942	Up-regulation
AGC_PKC_PKCa_PRKCB_ST	P48736	PIK3CG	P05771	PRKCB	S227	S227I	227	Missense	central	0	yes	1.324	0.000	EPSD	TCGA;ICGC	0.942	Loss
AGC_PKC_PKCa_PRKCB_ST	P48736	PIK3CG	P05771	PRKCB	S227	T228I	228	Missense	proximal	1	no	1.324	2.433	EPSD	TCGA;ICGC;COSMIC	0.942	Up-regulation
AGC_PKC_PKCa_PRKCB_ST	P48736	PIK3CG	P05771	PRKCB	S227	V223I	223	Missense	distal	-4	no	1.324	1.383	EPSD	TCGA;ICGC;COSMIC	0.942	Up-regulation
AGC_PKC_PKCa_PRKCB_ST	P48736	PIK3CG	P05771	PRKCB	S227	H225P	225	Missense	proximal	-2	no	1.324	1.507	EPSD	TCGA;ICGC;COSMIC	0.942	Up-regulation
AGC_PKC_PKCa_PRKCB_ST	P48736	PIK3CG	P05771	PRKCB	S227	I222V	222	Missense	distal	-5	no	1.324	1.262	EPSD	TCGA;ICGC;COSMIC	0.942	Down-regulation
AGC_PKC_PKCa_PRKCB_ST	P48736	PIK3CG	P05771	PRKCB	S227	R226H	226	Missense	proximal	-1	no	1.324	0.842	EPSD	TCGA;ICGC;COSMIC	0.942	Loss
AGC_PKC_PKCa_PRKCB_ST	P48736	PIK3CG	P05771	PRKCB	S417	P424S	424	Missense	distal	7	no	3.333	3.240	EPSD	TCGA;ICGC	0.942	Down-regulation
AGC_PKC_PKCa_PRKCB_ST	P48736	PIK3CG	P05771	PRKCB	S417	L423F	423	Missense	distal	6	no	3.333	3.205	EPSD	TCGA;ICGC;COSMIC	0.942	Down-regulation
AGC_PKC_PKCa_PRKCB_ST	P48736	PIK3CG	P05771	PRKCB	S417	P424L	424	Missense	distal	7	no	3.333	3.300	EPSD	TCGA;ICGC;COSMIC	0.942	Down-regulation
AGC_PKC_PKCa_PRKCB_ST	P48736	PIK3CG	P05771	PRKCB	S582	R579T	579	Missense	distal	-3	no	6.675	4.194	PhosphoSitePlus	TCGA;ICGC;COSMIC	0.942	Down-regulation
AGC_PKC_PKCa_PRKCB_ST	P48736	PIK3CG	P05771	PRKCB	S582	E581K	581	Missense	proximal	-1	no	6.675	6.819	PhosphoSitePlus	TCGA;ICGC;COSMIC	0.942	Up-regulation
AGC_PKC_PKCa_PRKCB_ST	P21730	C5AR1	P05771	PRKCB	S327	R320Q	320	Missense	distal	-7	no	1.648	1.673	EPSD	TCGA;ICGC;COSMIC	0.942	Up-regulation
AGC_PKC_PKCa_PRKCB_ST	P21730	C5AR1	P05771	PRKCB	S332	S338Y	338	Missense	distal	6	no	1.111	1.006	EPSD	TCGA;ICGC;COSMIC	0.942	Down-regulation
AGC_PKC_PKCa_PRKCB_ST	P21730	C5AR1	P05771	PRKCB	S334	S338Y	338	Missense	distal	4	no	0.990	1.405	PhosphoSitePlus	TCGA;ICGC;COSMIC	0.942	Up-regulation
AGC_PKC_PKCa_PRKCB_ST	P31749	AKT1	P05771	PRKCB	T308	G311D	311	Missense	distal	3	no	1.425	1.795	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC;GDSC;CCLE	0.942	Up-regulation
AGC_PKC_PKCa_PRKCB_ST	P31749	AKT1	P05771	PRKCB	S422	Y417C	417	Missense	distal	-5	no	2.176	2.084	EPSD	TCGA;ICGC;COSMIC	0.942	Down-regulation
AGC_PKC_PKCa_PRKCB_ST	P31749	AKT1	P05771	PRKCB	S422	P423T	423	Missense	proximal	1	no	2.176	2.137	EPSD	TCGA;ICGC	0.942	Down-regulation
AGC_PKC_PKCa_PRKCB_ST	P31749	AKT1	P05771	PRKCB	S422	E418K	418	Missense	distal	-4	no	2.176	1.913	EPSD	TCGA;ICGC	0.942	Down-regulation
AGC_PKC_PKCa_PRKCB_ST	Q9P2D0	IBTK	P05771	PRKCB	S695	R697S	697	Missense	proximal	2	no	2.838	-3.159	EPSD	TCGA;ICGC;COSMIC	0.942	Loss
AGC_PKC_PKCa_PRKCB_ST	Q9P2D0	IBTK	P05771	PRKCB	S695	S688G	688	Missense	distal	-7	no	2.838	2.919	EPSD	TCGA;ICGC	0.942	Up-regulation
AGC_PKC_PKCa_PRKCB_ST	Q9P2D0	IBTK	P05771	PRKCB	S695	K699E	699	Missense	distal	4	no	2.838	2.247	EPSD	TCGA;ICGC;COSMIC	0.942	Down-regulation
AGC_PKC_PKCa_PRKCB_ST	Q9P2D0	IBTK	P05771	PRKCB	S695	S700R	700	Missense	distal	5	no	2.838	3.245	EPSD	TCGA;ICGC;COSMIC	0.942	Up-regulation
AGC_PKC_PKCa_PRKCB_ST	Q9P2D0	IBTK	P05771	PRKCB	S765	V770G	770	Missense	distal	5	no	2.408	2.392	EPSD	TCGA	0.942	Down-regulation
AGC_PKC_PKCa_PRKCB_ST	Q9P2D0	IBTK	P05771	PRKCB	S765	M772L	772	Missense	distal	7	no	2.408	2.410	EPSD	TCGA;ICGC;COSMIC	0.942	Up-regulation
AGC_PKC_PKCa_PRKCB_ST	Q9P2D0	IBTK	P05771	PRKCB	S990	R987H	987	Missense	distal	-3	no	1.520	-1.467	EPSD	TCGA;ICGC;COSMIC	0.942	Loss
AGC_PKC_PKCa_PRKCB_ST	Q9P2D0	IBTK	P05771	PRKCB	S990	R989C	989	Missense	proximal	-1	no	1.520	0.816	EPSD	TCGA;ICGC;COSMIC	0.942	Loss
AGC_PKC_PKCa_PRKCB_ST	Q9P2D0	IBTK	P05771	PRKCB	S1096	I1094L	1094	Missense	proximal	-2	no	1.943	0.974	EPSD	TCGA;ICGC;COSMIC	0.942	Down-regulation
AGC_PKC_PKCa_PRKCB_ST	Q9P2D0	IBTK	P05771	PRKCB	S1154	S1148F	1148	Missense	distal	-6	no	9.095	8.989	EPSD	TCGA;ICGC;COSMIC	0.942	Down-regulation
AGC_PKC_PKCa_PRKCB_ST	Q9P2D0	IBTK	P05771	PRKCB	S1200	R1205W	1205	Missense	distal	5	no	4.542	3.847	PhosphoSitePlus;EPSD	TCGA;ICGC;COSMIC;GDSC	0.942	Down-regulation
AGC_PKC_PKCa_PRKCB_ST	Q9P2D0	IBTK	P05771	PRKCB	S1200	K1202T	1202	Missense	proximal	2	no	4.542	1.523	PhosphoSitePlus;EPSD	TCGA;ICGC;COSMIC	0.942	Down-regulation
AGC_PKC_PKCa_PRKCB_ST	Q9P2D0	IBTK	P05771	PRKCB	S1203	R1205W	1205	Missense	proximal	2	no	2.615	-6.898	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC;GDSC	0.942	Loss
AGC_PKC_PKCa_PRKCB_ST	Q9P2D0	IBTK	P05771	PRKCB	S1203	K1202T	1202	Missense	proximal	-1	no	2.615	2.371	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	0.942	Down-regulation
AGC_PKC_PKCa_PRKCB_ST	Q9UH77	KLHL3	P05771	PRKCB	S9	S10F	10	Missense	proximal	1	no	0.278	2.117	EPSD	TCGA;ICGC;COSMIC	0.942	Gain
AGC_PKC_PKCa_PRKCB_ST	Q9UH77	KLHL3	P05771	PRKCB	S10	S10F	10	Missense	central	0	yes	2.790	0.000	EPSD	TCGA;ICGC;COSMIC	0.942	Loss
AGC_PKC_PKCa_PRKCB_ST	Q9UH77	KLHL3	P05771	PRKCB	S10	Q15H	15	Missense	distal	5	no	2.790	2.390	EPSD	TCGA;ICGC;COSMIC	0.942	Down-regulation
AGC_PKC_PKCa_PRKCB_ST	P35568	IRS1	P05771	PRKCB	S24	R20C	20	Missense	distal	-4	no	1.120	1.626	EPSD	TCGA;ICGC;COSMIC	0.942	Up-regulation
AGC_PKC_PKCa_PRKCB_ST	P35568	IRS1	P05771	PRKCB	S24	R20H	20	Missense	distal	-4	no	1.120	1.427	EPSD	TCGA;ICGC	0.942	Up-regulation
AGC_PKC_PKCa_PRKCB_ST	P35568	IRS1	P05771	PRKCB	S193	V195M	195	Missense	proximal	2	no	2.556	1.097	EPSD	TCGA;ICGC;COSMIC	0.942	Down-regulation
AGC_PKC_PKCa_PRKCB_ST	P35568	IRS1	P05771	PRKCB	S268	E263K	263	Missense	distal	-5	no	3.296	3.370	EPSD	TCGA;ICGC;COSMIC	0.942	Up-regulation
AGC_PKC_PKCa_PRKCB_ST	P35568	IRS1	P05771	PRKCB	S268	K269N	269	Missense	proximal	1	no	3.296	0.477	EPSD	TCGA;ICGC;COSMIC	0.942	Loss
AGC_PKC_PKCa_PRKCB_ST	P35568	IRS1	P05771	PRKCB	S268	P266S	266	Missense	proximal	-2	no	3.296	3.175	EPSD	TCGA;ICGC;COSMIC	0.942	Down-regulation
AGC_PKC_PKCa_PRKCB_ST	P35568	IRS1	P05771	PRKCB	S268	S261I	261	Missense	distal	-7	no	3.296	3.133	EPSD	TCGA;ICGC;COSMIC	0.942	Down-regulation
AGC_PKC_PKCa_PRKCB_ST	P35568	IRS1	P05771	PRKCB	S268	N275S	275	Missense	distal	7	no	3.296	3.313	EPSD	TCGA;ICGC;COSMIC	0.942	Up-regulation
AGC_PKC_PKCa_PRKCB_ST	P35568	IRS1	P05771	PRKCB	S272	K269N	269	Missense	distal	-3	no	1.748	-1.413	EPSD	TCGA;ICGC;COSMIC	0.942	Loss
AGC_PKC_PKCa_PRKCB_ST	P35568	IRS1	P05771	PRKCB	S272	P266S	266	Missense	distal	-6	no	1.748	1.862	EPSD	TCGA;ICGC;COSMIC	0.942	Up-regulation
AGC_PKC_PKCa_PRKCB_ST	P35568	IRS1	P05771	PRKCB	S272	C276F	276	Missense	distal	4	no	1.748	1.720	EPSD	TCGA;ICGC;COSMIC	0.942	Down-regulation
AGC_PKC_PKCa_PRKCB_ST	P35568	IRS1	P05771	PRKCB	S272	N275S	275	Missense	distal	3	no	1.748	1.586	EPSD	TCGA;ICGC;COSMIC	0.942	Down-regulation
AGC_PKC_PKCa_PRKCB_ST	P35568	IRS1	P05771	PRKCB	S273	K269N	269	Missense	distal	-4	no	1.684	2.045	EPSD	TCGA;ICGC;COSMIC	0.942	Up-regulation
AGC_PKC_PKCa_PRKCB_ST	P35568	IRS1	P05771	PRKCB	S273	P266S	266	Missense	distal	-7	no	1.684	1.559	EPSD	TCGA;ICGC;COSMIC	0.942	Down-regulation
AGC_PKC_PKCa_PRKCB_ST	P35568	IRS1	P05771	PRKCB	S273	C276F	276	Missense	distal	3	no	1.684	1.509	EPSD	TCGA;ICGC;COSMIC	0.942	Down-regulation
AGC_PKC_PKCa_PRKCB_ST	P35568	IRS1	P05771	PRKCB	S273	N275S	275	Missense	proximal	2	no	1.684	0.965	EPSD	TCGA;ICGC;COSMIC	0.942	Down-regulation
AGC_PKC_PKCa_PRKCB_ST	P35568	IRS1	P05771	PRKCB	S307	A314G	314	Missense	distal	7	no	4.780	4.793	EPSD	TCGA;ICGC;COSMIC	0.942	Up-regulation
AGC_PKC_PKCa_PRKCB_ST	P35568	IRS1	P05771	PRKCB	S323	R327H	327	Missense	distal	4	no	8.318	7.496	PhosphoSitePlus;EPSD	TCGA;ICGC	0.942	Down-regulation
AGC_PKC_PKCa_PRKCB_ST	P35568	IRS1	P05771	PRKCB	S323	A328T	328	Missense	distal	5	no	8.318	8.256	PhosphoSitePlus;EPSD	TCGA;ICGC;COSMIC	0.942	Down-regulation
AGC_PKC_PKCa_PRKCB_ST	P35568	IRS1	P05771	PRKCB	S323	S330N	330	Missense	distal	7	no	8.318	8.301	PhosphoSitePlus;EPSD	TCGA;ICGC;COSMIC	0.942	Down-regulation
AGC_PKC_PKCa_PRKCB_ST	P35568	IRS1	P05771	PRKCB	S323	S323A	323	Missense	central	0	yes	8.318	0.000	PhosphoSitePlus;EPSD	TCGA;ICGC;COSMIC	0.942	Loss
AGC_PKC_PKCa_PRKCB_ST	P35568	IRS1	P05771	PRKCB	S323	P321L	321	Missense	proximal	-2	no	8.318	7.630	PhosphoSitePlus;EPSD	TCGA;ICGC;COSMIC	0.942	Down-regulation
AGC_PKC_PKCa_PRKCB_ST	P35568	IRS1	P05771	PRKCB	T351	A356T	356	Missense	distal	5	no	2.051	1.989	EPSD	TCGA;ICGC;COSMIC	0.942	Down-regulation
AGC_PKC_PKCa_PRKCB_ST	P35568	IRS1	P05771	PRKCB	T351	P346H	346	Missense	distal	-5	no	2.051	2.077	EPSD	TCGA;ICGC	0.942	Up-regulation
AGC_PKC_PKCa_PRKCB_ST	P35568	IRS1	P05771	PRKCB	S362	A363D	363	Missense	proximal	1	no	4.417	4.128	EPSD	TCGA;ICGC;COSMIC	0.942	Down-regulation
AGC_PKC_PKCa_PRKCB_ST	P35568	IRS1	P05771	PRKCB	S362	A356T	356	Missense	distal	-6	no	4.417	4.558	EPSD	TCGA;ICGC;COSMIC	0.942	Up-regulation
AGC_PKC_PKCa_PRKCB_ST	P35568	IRS1	P05771	PRKCB	S362	A363T	363	Missense	proximal	1	no	4.417	3.971	EPSD	TCGA;ICGC;COSMIC	0.942	Down-regulation
AGC_PKC_PKCa_PRKCB_ST	P35568	IRS1	P05771	PRKCB	S362	R360W	360	Missense	proximal	-2	no	4.417	1.141	EPSD	TCGA;ICGC;CCLE	0.942	Down-regulation
AGC_PKC_PKCa_PRKCB_ST	P35568	IRS1	P05771	PRKCB	S362	H359R	359	Missense	distal	-3	no	4.417	7.404	EPSD	TCGA;ICGC	0.942	Up-regulation
AGC_PKC_PKCa_PRKCB_ST	P35568	IRS1	P05771	PRKCB	S380	R373C	373	Missense	distal	-7	no	0.826	1.041	EPSD	TCGA;ICGC;COSMIC	0.942	Gain
AGC_PKC_PKCa_PRKCB_ST	P35568	IRS1	P05771	PRKCB	S413	R411Q	411	Missense	proximal	-2	no	1.222	0.250	EPSD	TCGA;ICGC	0.942	Loss
AGC_PKC_PKCa_PRKCB_ST	P35568	IRS1	P05771	PRKCB	S441	F438V	438	Missense	distal	-3	no	7.878	8.846	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	0.942	Up-regulation
AGC_PKC_PKCa_PRKCB_ST	P35568	IRS1	P05771	PRKCB	S441	V445I	445	Missense	distal	4	no	7.878	7.938	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	0.942	Up-regulation
AGC_PKC_PKCa_PRKCB_ST	P35568	IRS1	P05771	PRKCB	S441	R443H	443	Missense	proximal	2	no	7.878	1.516	EPSD;PhosphoSitePlus	TCGA;ICGC	0.942	Down-regulation
AGC_PKC_PKCa_PRKCB_ST	P35568	IRS1	P05771	PRKCB	S581	E588D	588	Missense	distal	7	no	1.534	1.476	EPSD	TCGA;ICGC;COSMIC	0.942	Down-regulation
AGC_PKC_PKCa_PRKCB_ST	P35568	IRS1	P05771	PRKCB	S581	S581Y	581	Missense	central	0	yes	1.534	0.000	EPSD	TCGA;ICGC;COSMIC	0.942	Loss
AGC_PKC_PKCa_PRKCB_ST	P35568	IRS1	P05771	PRKCB	S603	H607R	607	Missense	distal	4	no	2.483	3.305	EPSD	TCGA;ICGC	0.942	Up-regulation
AGC_PKC_PKCa_PRKCB_ST	P35568	IRS1	P05771	PRKCB	S603	R600C	600	Missense	distal	-3	no	2.483	-1.417	EPSD	TCGA;ICGC;COSMIC	0.942	Loss
AGC_PKC_PKCa_PRKCB_ST	P35568	IRS1	P05771	PRKCB	T605	H607R	607	Missense	proximal	2	no	-4.283	2.079	EPSD	TCGA;ICGC	0.942	Gain
AGC_PKC_PKCa_PRKCB_ST	P35568	IRS1	P05771	PRKCB	S795	R797C	797	Missense	proximal	2	no	3.003	-1.490	EPSD	TCGA;ICGC;COSMIC	0.942	Loss
AGC_PKC_PKCa_PRKCB_ST	P35568	IRS1	P05771	PRKCB	S1025	E1023K	1023	Missense	proximal	-2	no	-0.271	1.174	EPSD	TCGA;ICGC;COSMIC	0.942	Gain
AGC_PKC_PKCa_PRKCB_ST	P35568	IRS1	P05771	PRKCB	S1084	R1081H	1081	Missense	distal	-3	no	6.007	3.020	EPSD	TCGA;ICGC;COSMIC	0.942	Down-regulation
AGC_PKC_PKCa_PRKCB_ST	P35568	IRS1	P05771	PRKCB	S1084	R1089C	1089	Missense	distal	5	no	6.007	5.563	EPSD	TCGA;ICGC;COSMIC	0.942	Down-regulation
AGC_PKC_PKCa_PRKCB_ST	P35568	IRS1	P05771	PRKCB	S1218	S1223G	1223	Missense	distal	5	no	2.552	2.529	EPSD	TCGA;ICGC;COSMIC	0.942	Down-regulation
AGC_PKC_PKCa_PRKCB_ST	P35568	IRS1	P05771	PRKCB	T1219	S1223G	1223	Missense	distal	4	no	3.984	3.645	EPSD	TCGA;ICGC;COSMIC	0.942	Down-regulation
AGC_PKC_PKCa_PRKCB_ST	Q13131	PRKAA1	P05771	PRKCB	S6	R2H	2	Missense	distal	-4	no	4.131	4.438	EPSD	TCGA;ICGC;COSMIC	0.942	Up-regulation
AGC_PKC_PKCa_PRKCB_ST	P11171	EPB41	P05771	PRKCB	S104	E103K	103	Missense	proximal	-1	no	2.786	2.930	EPSD	TCGA;ICGC	0.942	Up-regulation
AGC_PKC_PKCa_PRKCB_ST	P11171	EPB41	P05771	PRKCB	S180	E177Q	177	Missense	distal	-3	no	1.126	1.032	EPSD	TCGA;ICGC;COSMIC	0.942	Down-regulation
AGC_PKC_PKCa_PRKCB_ST	P11171	EPB41	P05771	PRKCB	S180	G173E	173	Missense	distal	-7	no	1.126	0.934	EPSD	TCGA;ICGC;COSMIC	0.942	Loss
AGC_PKC_PKCa_PRKCB_ST	P11171	EPB41	P05771	PRKCB	S188	Q190E	190	Missense	proximal	2	no	1.715	1.226	EPSD	TCGA;ICGC;COSMIC	0.942	Down-regulation
AGC_PKC_PKCa_PRKCB_ST	P11171	EPB41	P05771	PRKCB	S200	S200F	200	Missense	central	0	yes	4.920	0.000	EPSD	TCGA;ICGC;COSMIC	0.942	Loss
AGC_PKC_PKCa_PRKCB_ST	P11171	EPB41	P05771	PRKCB	S200	L197S	197	Missense	distal	-3	no	4.920	5.680	EPSD	TCGA;ICGC;COSMIC	0.942	Up-regulation
AGC_PKC_PKCa_PRKCB_ST	P11171	EPB41	P05771	PRKCB	S441	R444C	444	Missense	distal	3	no	2.927	2.074	EPSD	TCGA;ICGC;COSMIC	0.942	Down-regulation
AGC_PKC_PKCa_PRKCB_ST	P11171	EPB41	P05771	PRKCB	S441	V437A	437	Missense	distal	-4	no	2.927	3.070	EPSD	TCGA;ICGC;COSMIC	0.942	Up-regulation
AGC_PKC_PKCa_PRKCB_ST	P11171	EPB41	P05771	PRKCB	S446	R444C	444	Missense	proximal	-2	no	4.381	2.915	EPSD	TCGA;ICGC;COSMIC	0.942	Down-regulation
AGC_PKC_PKCa_PRKCB_ST	P11171	EPB41	P05771	PRKCB	S446	K450T	450	Missense	distal	4	no	4.381	3.449	EPSD	TCGA;ICGC	0.942	Down-regulation
AGC_PKC_PKCa_PRKCB_ST	P11171	EPB41	P05771	PRKCB	S469	P468A	468	Missense	proximal	-1	no	6.823	6.911	EPSD	TCGA;ICGC;COSMIC	0.942	Up-regulation
AGC_PKC_PKCa_PRKCB_ST	P11171	EPB41	P05771	PRKCB	S469	A472S	472	Missense	distal	3	no	6.823	7.037	EPSD	TCGA;ICGC;COSMIC	0.942	Up-regulation
AGC_PKC_PKCa_PRKCB_ST	P11171	EPB41	P05771	PRKCB	S469	L467R	467	Missense	proximal	-2	no	6.823	9.343	EPSD	TCGA;ICGC	0.942	Up-regulation
AGC_PKC_PKCa_PRKCB_ST	P11171	EPB41	P05771	PRKCB	S469	R471Q	471	Missense	proximal	2	no	6.823	0.274	EPSD	TCGA;ICGC;COSMIC	0.942	Loss
AGC_PKC_PKCa_PRKCB_ST	P11171	EPB41	P05771	PRKCB	S510	Y509H	509	Missense	proximal	-1	no	3.136	3.016	EPSD	TCGA;ICGC	0.942	Down-regulation
AGC_PKC_PKCa_PRKCB_ST	P11171	EPB41	P05771	PRKCB	S510	K506T	506	Missense	distal	-4	no	3.136	3.465	EPSD	TCGA;ICGC	0.942	Up-regulation
AGC_PKC_PKCa_PRKCB_ST	P11171	EPB41	P05771	PRKCB	S521	A520V	520	Missense	proximal	-1	no	1.966	2.070	EPSD	TCGA;ICGC;COSMIC	0.942	Up-regulation
AGC_PKC_PKCa_PRKCB_ST	P11171	EPB41	P05771	PRKCB	S521	R518G	518	Missense	distal	-3	no	1.966	-2.250	EPSD	TCGA;ICGC;COSMIC	0.942	Loss
AGC_PKC_PKCa_PRKCB_ST	P11171	EPB41	P05771	PRKCB	S536	R533C	533	Missense	distal	-3	no	9.014	5.115	EPSD	TCGA;ICGC	0.942	Down-regulation
AGC_PKC_PKCa_PRKCB_ST	P11171	EPB41	P05771	PRKCB	S536	K537E	537	Missense	proximal	1	no	9.014	7.023	EPSD	TCGA;ICGC;COSMIC	0.942	Down-regulation
AGC_PKC_PKCa_PRKCB_ST	P11171	EPB41	P05771	PRKCB	S536	R533H	533	Missense	distal	-3	no	9.014	6.028	EPSD	TCGA;ICGC;COSMIC	0.942	Down-regulation
AGC_PKC_PKCa_PRKCB_ST	P11171	EPB41	P05771	PRKCB	S540	R533C	533	Missense	distal	-7	no	3.582	3.798	EPSD	TCGA;ICGC	0.942	Up-regulation
AGC_PKC_PKCa_PRKCB_ST	P11171	EPB41	P05771	PRKCB	S540	K537E	537	Missense	distal	-3	no	3.582	0.247	EPSD	TCGA;ICGC;COSMIC	0.942	Loss
AGC_PKC_PKCa_PRKCB_ST	P11171	EPB41	P05771	PRKCB	S540	R533H	533	Missense	distal	-7	no	3.582	3.908	EPSD	TCGA;ICGC;COSMIC	0.942	Up-regulation
AGC_PKC_PKCa_PRKCB_ST	P11171	EPB41	P05771	PRKCB	S555	S551L	551	Missense	distal	-4	no	2.845	2.904	EPSD	TCGA;ICGC;COSMIC	0.942	Up-regulation
AGC_PKC_PKCa_PRKCB_ST	P11171	EPB41	P05771	PRKCB	S709	R707C	707	Missense	proximal	-2	no	3.383	1.917	EPSD	TCGA;COSMIC	0.942	Down-regulation
AGC_PKC_PKCa_PRKCB_ST	P11171	EPB41	P05771	PRKCB	S709	R707H	707	Missense	proximal	-2	no	3.383	1.368	EPSD	TCGA;COSMIC;CCLE	0.942	Down-regulation
AGC_PKC_PKCa_PRKCB_ST	P11171	EPB41	P05771	PRKCB	S709	R715Q	715	Missense	distal	6	no	3.383	2.577	EPSD	TCGA;COSMIC	0.942	Down-regulation
AGC_PKC_PKCa_PRKCB_ST	P11171	EPB41	P05771	PRKCB	T736	V737I	737	Missense	proximal	1	no	1.884	2.171	EPSD	TCGA;COSMIC	0.942	Up-regulation
AGC_PKC_PKCa_PRKCB_ST	P11171	EPB41	P05771	PRKCB	S812	E813K	813	Missense	proximal	1	no	-0.065	1.926	EPSD	TCGA;COSMIC	0.942	Gain
AGC_PKC_PKCa_PRKCB_ST	P16949	STMN1	P05771	PRKCB	S25	S31Y	31	Missense	distal	6	no	1.193	1.089	PhosphoSitePlus;EPSD	TCGA;COSMIC	0.942	Down-regulation
AGC_PKC_PKCa_PRKCB_ST	P16949	STMN1	P05771	PRKCB	S25	S28P	28	Missense	distal	3	no	1.193	1.260	PhosphoSitePlus;EPSD	TCGA;ICGC	0.942	Up-regulation
AGC_PKC_PKCa_PRKCB_ST	P16949	STMN1	P05771	PRKCB	S25	K29I	29	Missense	distal	4	no	1.193	0.432	PhosphoSitePlus;EPSD	TCGA;ICGC;COSMIC	0.942	Loss
AGC_PKC_PKCa_PRKCB_ST	P16949	STMN1	P05771	PRKCB	S31	S28P	28	Missense	distal	-3	no	0.894	1.078	EPSD	TCGA;ICGC	0.942	Gain
AGC_PKC_PKCa_PRKCB_ST	P16949	STMN1	P05771	PRKCB	S63	E58D	58	Missense	distal	-5	no	0.957	0.930	EPSD	TCGA;ICGC;COSMIC	0.942	Loss
AGC_PKC_PKCa_PRKCB_ST	P16949	STMN1	P05771	PRKCB	S63	A66G	66	Missense	distal	3	no	0.957	0.908	EPSD	TCGA;ICGC;COSMIC	0.942	Loss
AGC_PKC_PKCa_PRKCB_ST	P16949	STMN1	P05771	PRKCB	S63	R61H	61	Missense	proximal	-2	no	0.957	-1.058	EPSD	TCGA;ICGC;COSMIC	0.942	Loss
AGC_PKC_PKCa_PRKCB_ST	P16949	STMN1	P05771	PRKCB	S63	S63P	63	Missense	central	0	yes	0.957	0.000	EPSD	TCGA;ICGC;COSMIC	0.942	Loss
AGC_PKC_PKCa_PRKCB_ST	P14679	TYR	P05771	PRKCB	S339	F338V	338	Missense	proximal	-1	no	6.771	6.754	EPSD	TCGA;ICGC	0.942	Down-regulation
AGC_PKC_PKCa_PRKCB_ST	P14679	TYR	P05771	PRKCB	S339	R341I	341	Missense	proximal	2	no	6.771	1.489	EPSD	TCGA;ICGC	0.942	Down-regulation
AGC_PKC_PKCa_PRKCB_ST	P28329	CHAT	P05771	PRKCB	T373	D379Y	379	Missense	distal	6	no	4.094	3.766	EPSD	TCGA;COSMIC	0.942	Down-regulation
AGC_PKC_PKCa_PRKCB_ST	P28329	CHAT	P05771	PRKCB	T373	S377L	377	Missense	distal	4	no	4.094	3.806	EPSD	TCGA;COSMIC	0.942	Down-regulation
AGC_PKC_PKCa_PRKCB_ST	P28329	CHAT	P05771	PRKCB	S377	D379Y	379	Missense	proximal	2	no	1.429	1.612	EPSD	TCGA;COSMIC	0.942	Up-regulation
AGC_PKC_PKCa_PRKCB_ST	P28329	CHAT	P05771	PRKCB	S377	S377L	377	Missense	central	0	yes	1.429	0.000	EPSD	TCGA;COSMIC	0.942	Loss
AGC_PKC_PKCa_PRKCB_ST	P28329	CHAT	P05771	PRKCB	T462	H460L	460	Missense	proximal	-2	no	1.163	0.658	EPSD	TCGA;COSMIC	0.942	Loss
AGC_PKC_PKCa_PRKCB_ST	P28329	CHAT	P05771	PRKCB	T462	L457M	457	Missense	distal	-5	no	1.163	1.171	EPSD	TCGA;COSMIC	0.942	Up-regulation
AGC_PKC_PKCa_PRKCB_ST	P28329	CHAT	P05771	PRKCB	T462	R466K	466	Missense	distal	4	no	1.163	1.048	EPSD	TCGA;COSMIC	0.942	Down-regulation
AGC_PKC_PKCa_PRKCB_ST	P28329	CHAT	P05771	PRKCB	S464	H460L	460	Missense	distal	-4	no	5.753	5.830	EPSD	TCGA;COSMIC	0.942	Up-regulation
AGC_PKC_PKCa_PRKCB_ST	P28329	CHAT	P05771	PRKCB	S464	L457M	457	Missense	distal	-7	no	5.753	5.866	EPSD	TCGA;COSMIC	0.942	Up-regulation
AGC_PKC_PKCa_PRKCB_ST	P28329	CHAT	P05771	PRKCB	S464	R470Q	470	Missense	distal	6	no	5.753	4.948	EPSD	TCGA;COSMIC	0.942	Down-regulation
AGC_PKC_PKCa_PRKCB_ST	P28329	CHAT	P05771	PRKCB	S464	R466K	466	Missense	proximal	2	no	5.753	4.129	EPSD	TCGA;COSMIC	0.942	Down-regulation
AGC_PKC_PKCa_PRKCB_ST	P28329	CHAT	P05771	PRKCB	S465	H460L	460	Missense	distal	-5	no	4.475	4.468	EPSD	TCGA;COSMIC	0.942	Down-regulation
AGC_PKC_PKCa_PRKCB_ST	P28329	CHAT	P05771	PRKCB	S465	R470Q	470	Missense	distal	5	no	4.475	4.498	EPSD	TCGA;COSMIC	0.942	Up-regulation
AGC_PKC_PKCa_PRKCB_ST	P28329	CHAT	P05771	PRKCB	S465	R466K	466	Missense	proximal	1	no	4.475	4.589	EPSD	TCGA;COSMIC	0.942	Up-regulation
AGC_PKC_PKCa_PRKCB_ST	P28329	CHAT	P05771	PRKCB	S558	A557V	557	Missense	proximal	-1	no	6.129	6.233	EPSD	TCGA;COSMIC	0.942	Up-regulation
AGC_PKC_PKCa_PRKCB_ST	P28329	CHAT	P05771	PRKCB	S558	P552L	552	Missense	distal	-6	no	6.129	6.144	EPSD	TCGA;COSMIC	0.942	Up-regulation
AGC_PKC_PKCa_PRKCB_ST	P28329	CHAT	P05771	PRKCB	S558	S556R	556	Missense	proximal	-2	no	6.129	8.081	EPSD	TCGA;COSMIC	0.942	Up-regulation
AGC_PKC_PKCa_PRKCB_ST	P28329	CHAT	P05771	PRKCB	S558	G565E	565	Missense	distal	7	no	6.129	5.960	EPSD	TCGA;COSMIC	0.942	Down-regulation
AGC_PKC_PKCa_PRKCB_ST	Q12906	ILF3	P05771	PRKCB	S19	S19Y	19	Missense	central	0	yes	1.596	0.000	EPSD	TCGA;COSMIC	0.942	Loss
AGC_PKC_PKCa_PRKCB_ST	Q12906	ILF3	P05771	PRKCB	S19	K17N	17	Missense	proximal	-2	no	1.596	-0.236	EPSD	TCGA;ICGC	0.942	Loss
AGC_PKC_PKCa_PRKCB_ST	Q12906	ILF3	P05771	PRKCB	S19	R12C	12	Missense	distal	-7	no	1.596	1.811	EPSD	TCGA;ICGC	0.942	Up-regulation
AGC_PKC_PKCa_PRKCB_ST	Q12906	ILF3	P05771	PRKCB	S19	Y22C	22	Missense	distal	3	no	1.596	1.522	EPSD	TCGA;ICGC;COSMIC	0.942	Down-regulation
AGC_PKC_PKCa_PRKCB_ST	Q12906	ILF3	P05771	PRKCB	S19	R12H	12	Missense	distal	-7	no	1.596	1.921	EPSD	TCGA;ICGC	0.942	Up-regulation
AGC_PKC_PKCa_PRKCB_ST	Q12906	ILF3	P05771	PRKCB	S19	K17R	17	Missense	proximal	-2	no	1.596	1.486	EPSD	TCGA;ICGC	0.942	Down-regulation
AGC_PKC_PKCa_PRKCB_ST	Q12906	ILF3	P05771	PRKCB	S19	E26V	26	Missense	distal	7	no	1.596	1.696	EPSD	TCGA	0.942	Up-regulation
AGC_PKC_PKCa_PRKCB_ST	Q12906	ILF3	P05771	PRKCB	S20	S19Y	19	Missense	proximal	-1	no	2.945	3.187	EPSD	TCGA;COSMIC	0.942	Up-regulation
AGC_PKC_PKCa_PRKCB_ST	Q12906	ILF3	P05771	PRKCB	S20	K17N	17	Missense	distal	-3	no	2.945	-0.216	EPSD	TCGA;ICGC	0.942	Loss
AGC_PKC_PKCa_PRKCB_ST	Q12906	ILF3	P05771	PRKCB	S20	Y22C	22	Missense	proximal	2	no	2.945	4.914	EPSD	TCGA;ICGC;COSMIC	0.942	Up-regulation
AGC_PKC_PKCa_PRKCB_ST	Q12906	ILF3	P05771	PRKCB	S20	K17R	17	Missense	distal	-3	no	2.945	2.714	EPSD	TCGA;ICGC	0.942	Down-regulation
AGC_PKC_PKCa_PRKCB_ST	Q12906	ILF3	P05771	PRKCB	S20	E26V	26	Missense	distal	6	no	2.945	2.038	EPSD	TCGA	0.942	Down-regulation
AGC_PKC_PKCa_PRKCB_ST	Q12906	ILF3	P05771	PRKCB	S73	E75K	75	Missense	proximal	2	no	-4.360	1.054	EPSD	TCGA;ICGC	0.942	Gain
AGC_PKC_PKCa_PRKCB_ST	Q12906	ILF3	P05771	PRKCB	S382	P383L	383	Missense	proximal	1	no	2.280	3.416	EPSD	TCGA;ICGC;COSMIC	0.942	Up-regulation
AGC_PKC_PKCa_PRKCB_ST	Q12906	ILF3	P05771	PRKCB	S384	P383L	383	Missense	proximal	-1	no	5.050	5.101	EPSD	TCGA;ICGC;COSMIC	0.942	Up-regulation
AGC_PKC_PKCa_PRKCB_ST	Q12906	ILF3	P05771	PRKCB	S482	E484K	484	Missense	proximal	2	no	-2.736	2.678	EPSD	TCGA;ICGC;COSMIC	0.942	Gain
AGC_PKC_PKCa_PRKCB_ST	Q12906	ILF3	P05771	PRKCB	S647	G650V	650	Missense	distal	3	no	10.233	10.127	PhosphoSitePlus	TCGA;COSMIC	0.942	Down-regulation
AGC_PKC_PKCa_PRKCB_ST	P49840	GSK3A	P05771	PRKCB	S266	D263N	263	Missense	distal	-3	no	2.948	3.917	EPSD	TCGA;ICGC	0.942	Up-regulation
AGC_PKC_PKCa_PRKCB_ST	P49840	GSK3A	P05771	PRKCB	S266	L270W	270	Missense	distal	4	no	2.948	2.511	EPSD	TCGA;ICGC;COSMIC	0.942	Down-regulation
AGC_PKC_PKCa_PRKCB_ST	P49840	GSK3A	P05771	PRKCB	S266	C262R	262	Missense	distal	-4	no	2.948	2.442	EPSD	TCGA;ICGC;COSMIC	0.942	Down-regulation
AGC_PKC_PKCa_PRKCB_ST	P49840	GSK3A	P05771	PRKCB	S266	G265D	265	Missense	proximal	-1	no	2.948	3.074	EPSD	TCGA;ICGC	0.942	Up-regulation
AGC_PKC_PKCa_PRKCB_ST	P49840	GSK3A	P05771	PRKCB	S266	Q269P	269	Missense	distal	3	no	2.948	2.814	EPSD	TCGA;ICGC	0.942	Down-regulation
CAMK_CAMKL_PASK_PASK_ST	Q96RG2	PASK	Q96RG2	PASK	S104	E100K	100	Missense	distal	-4	no	1.476	1.952	EPSD	TCGA;ICGC;COSMIC	1.643	Gain
CAMK_CAMKL_PASK_PASK_ST	Q96RG2	PASK	Q96RG2	PASK	S120	P121S	121	Missense	proximal	1	no	1.191	1.785	EPSD	TCGA;ICGC;COSMIC	1.643	Gain
CAMK_CAMKL_PASK_PASK_ST	Q96RG2	PASK	Q96RG2	PASK	T512	A513V	513	Missense	proximal	1	no	2.316	2.383	EPSD	TCGA;ICGC;COSMIC	1.643	Up-regulation
CAMK_CAMKL_PASK_PASK_ST	Q96RG2	PASK	Q96RG2	PASK	T850	V847L	847	Missense	distal	-3	no	2.078	2.009	EPSD	TCGA;ICGC;COSMIC	1.643	Down-regulation
CAMK_CAMKL_PASK_PASK_ST	Q96RG2	PASK	Q96RG2	PASK	T850	H846Y	846	Missense	distal	-4	no	2.078	2.008	EPSD	TCGA;ICGC;COSMIC	1.643	Down-regulation
CAMK_CAMKL_PASK_PASK_ST	Q96RG2	PASK	Q96RG2	PASK	T1001	S996F	996	Missense	distal	-5	no	1.994	1.984	EPSD	TCGA;ICGC;COSMIC	1.643	Down-regulation
CAMK_CAMKL_PASK_PASK_ST	P68104	EEF1A1	Q96RG2	PASK	T82	Y85H	85	Missense	distal	3	no	1.838	1.146	EPSD	TCGA;ICGC;COSMIC	1.643	Loss
CAMK_CAMKL_PASK_PASK_ST	P68104	EEF1A1	Q96RG2	PASK	S83	Y85H	85	Missense	proximal	2	no	1.859	1.504	EPSD	TCGA;ICGC;COSMIC	1.643	Loss
CAMK_CAMKL_PASK_PASK_ST	P68104	EEF1A1	Q96RG2	PASK	S83	I90T	90	Missense	distal	7	no	1.859	1.876	EPSD	TCGA;ICGC;COSMIC	1.643	Up-regulation
CAMK_CAMKL_PASK_PASK_ST	P68104	EEF1A1	Q96RG2	PASK	T432	Q431E	431	Missense	proximal	-1	no	4.305	4.293	PhosphoSitePlus	TCGA;ICGC;COSMIC	1.643	Down-regulation
CAMK_CAMKL_PASK_PASK_ST	P68104	EEF1A1	Q96RG2	PASK	T432	R430T	430	Missense	proximal	-2	no	4.305	4.235	PhosphoSitePlus	TCGA;ICGC;COSMIC	1.643	Down-regulation
CAMK_CAMKL_PASK_PASK_ST	P68104	EEF1A1	Q96RG2	PASK	T432	V433F	433	Missense	proximal	1	no	4.305	4.138	PhosphoSitePlus	TCGA;ICGC;COSMIC	1.643	Down-regulation
CAMK_CAMKL_PASK_PASK_ST	P68104	EEF1A1	Q96RG2	PASK	T432	T432I	432	Missense	central	0	yes	4.305	0.000	PhosphoSitePlus	TCGA;ICGC;COSMIC	1.643	Loss
CAMK_CAMKL_PASK_PASK_ST	P68104	EEF1A1	Q96RG2	PASK	T432	M429V	429	Missense	distal	-3	no	4.305	4.200	PhosphoSitePlus	TCGA;ICGC;COSMIC	1.643	Down-regulation
CAMK_CAMKL_PASK_PASK_ST	P68104	EEF1A1	Q96RG2	PASK	T432	A434T	434	Missense	proximal	2	no	4.305	4.364	PhosphoSitePlus	TCGA;ICGC;COSMIC	1.643	Up-regulation
CAMK_CAMKL_PASK_PASK_ST	P68104	EEF1A1	Q96RG2	PASK	T432	R427C	427	Missense	distal	-5	no	4.305	4.014	PhosphoSitePlus	TCGA;ICGC;COSMIC	1.643	Down-regulation
CAMK_CAMKL_PASK_PASK_ST	P68104	EEF1A1	Q96RG2	PASK	T432	A434V	434	Missense	proximal	2	no	4.305	4.338	PhosphoSitePlus	TCGA;COSMIC	1.643	Up-regulation
Other_TOPK_PBK_ST	Q96S44	TP53RK	Q96KB5	PBK	S250	R243C	243	Missense	distal	-7	no	3.353	3.345	PhosphoSitePlus	TCGA;GDSC	2.342	Down-regulation
Other_TOPK_PBK_ST	P05412	JUN	Q96KB5	PBK	S73	S73L	73	Missense	central	0	yes	5.452	0.000	PhosphoSitePlus;EPSD	TCGA;ICGC;COSMIC	2.342	Loss
Other_TOPK_PBK_ST	P05412	JUN	Q96KB5	PBK	T297	Q290H	290	Missense	distal	-7	no	2.493	2.482	EPSD	TCGA;ICGC;COSMIC	2.342	Down-regulation
Other_TOPK_PBK_ST	P05412	JUN	Q96KB5	PBK	T297	S296Y	296	Missense	proximal	-1	no	2.493	2.449	EPSD	TCGA;ICGC;COSMIC	2.342	Down-regulation
Other_TOPK_PBK_ST	P81274	GPSM2	Q96KB5	PBK	S567	R573C	573	Missense	distal	6	no	2.571	2.563	EPSD	TCGA;ICGC;COSMIC	2.342	Down-regulation
Other_TOPK_PBK_ST	Q06830	PRDX1	Q96KB5	PBK	S32	D33G	33	Missense	proximal	1	no	5.543	5.448	PhosphoSitePlus	TCGA;ICGC;COSMIC	2.342	Down-regulation
Other_TOPK_PBK_ST	Q06830	PRDX1	Q96KB5	PBK	S32	D28Y	28	Missense	distal	-4	no	5.543	5.411	PhosphoSitePlus	TCGA;ICGC;COSMIC	2.342	Down-regulation
Other_TOPK_PBK_ST	Q06830	PRDX1	Q96KB5	PBK	S106	P108S	108	Missense	proximal	2	no	2.591	2.592	EPSD	TCGA;ICGC;COSMIC	2.342	Up-regulation
Other_PEK_PEK_EIF2AK3_ST	P05198	EIF2S1	Q9NZJ5	EIF2AK3	S49	M45I	45	Missense	distal	-4	no	4.319	4.348	PhosphoSitePlus;EPSD	TCGA;ICGC;COSMIC	0.763	Up-regulation
Other_PEK_PEK_EIF2AK3_ST	P05198	EIF2S1	Q9NZJ5	EIF2AK3	S49	G44C	44	Missense	distal	-5	no	4.319	4.283	PhosphoSitePlus;EPSD	TCGA;ICGC;COSMIC	0.763	Down-regulation
Other_PEK_PEK_EIF2AK3_ST	P05198	EIF2S1	Q9NZJ5	EIF2AK3	S52	M45I	45	Missense	distal	-7	no	3.905	3.925	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	0.763	Up-regulation
Other_PEK_PEK_EIF2AK3_ST	P05198	EIF2S1	Q9NZJ5	EIF2AK3	S52	R57C	57	Missense	distal	5	no	3.905	3.189	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	0.763	Down-regulation
TKL_RAF_RAF_BRAF_ST	P19634	SLC9A1	P15056	BRAF	S359	A355V	355	Missense	distal	-4	no	1.968	2.458	EPSD	TCGA;COSMIC	2.269	Gain
TKL_RAF_RAF_BRAF_ST	P19634	SLC9A1	P15056	BRAF	T653	T653M	653	Missense	central	0	yes	4.142	0.000	PhosphoSitePlus	TCGA;ICGC;COSMIC	2.269	Loss
TKL_RAF_RAF_BRAF_ST	Q92934	BAD	P15056	BRAF	S75	S71I	71	Missense	distal	-4	no	4.371	5.022	PhosphoSitePlus;EPSD	TCGA;ICGC;COSMIC	2.269	Up-regulation
TKL_RAF_RAF_BRAF_ST	Q92934	BAD	P15056	BRAF	S99	A100T	100	Missense	proximal	1	no	4.087	4.073	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	2.269	Down-regulation
TKL_RAF_RAF_BRAF_ST	Q92934	BAD	P15056	BRAF	S118	M117I	117	Missense	proximal	-1	no	4.381	4.226	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	2.269	Down-regulation
TKL_RAF_RAF_BRAF_ST	Q92934	BAD	P15056	BRAF	S134	R131H	131	Missense	distal	-3	no	4.161	3.907	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	2.269	Down-regulation
TKL_RAF_RAF_BRAF_ST	Q92934	BAD	P15056	BRAF	S134	G136D	136	Missense	proximal	2	no	4.161	4.195	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	2.269	Up-regulation
TKL_RAF_RAF_BRAF_ST	Q92934	BAD	P15056	BRAF	S134	S134I	134	Missense	central	0	yes	4.161	0.000	EPSD;PhosphoSitePlus	TCGA	2.269	Loss
TKL_RAF_RAF_BRAF_ST	P68104	EEF1A1	P15056	BRAF	S21	L27V	27	Missense	distal	6	no	4.317	4.343	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	2.269	Up-regulation
TKL_RAF_RAF_BRAF_ST	P68104	EEF1A1	P15056	BRAF	S21	D17N	17	Missense	distal	-4	no	4.317	4.399	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	2.269	Up-regulation
TKL_RAF_RAF_BRAF_ST	P68104	EEF1A1	P15056	BRAF	S21	I28V	28	Missense	distal	7	no	4.317	4.174	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	2.269	Down-regulation
TKL_RAF_RAF_BRAF_ST	P68104	EEF1A1	P15056	BRAF	T88	D91N	91	Missense	distal	3	no	3.164	3.061	PhosphoSitePlus;EPSD	TCGA;ICGC;COSMIC	2.269	Down-regulation
TKL_RAF_RAF_BRAF_ST	P68104	EEF1A1	P15056	BRAF	T88	A92T	92	Missense	distal	4	no	3.164	3.132	PhosphoSitePlus;EPSD	TCGA;ICGC;COSMIC	2.269	Down-regulation
TKL_RAF_RAF_BRAF_ST	P68104	EEF1A1	P15056	BRAF	T88	Y85H	85	Missense	distal	-3	no	3.164	3.042	PhosphoSitePlus;EPSD	TCGA;ICGC;COSMIC	2.269	Down-regulation
TKL_RAF_RAF_BRAF_ST	P68104	EEF1A1	P15056	BRAF	T88	I90T	90	Missense	proximal	2	no	3.164	3.147	PhosphoSitePlus;EPSD	TCGA;ICGC;COSMIC	2.269	Down-regulation
TKL_RAF_RAF_BRAF_ST	Q9H9S0	NANOG	P15056	BRAF	S57	M58I	58	Missense	proximal	1	no	2.653	2.656	EPSD	TCGA;ICGC;COSMIC;CCLE	2.269	Up-regulation
TKL_RAF_RAF_BRAF_ST	Q9H9S0	NANOG	P15056	BRAF	S57	T50N	50	Missense	distal	-7	no	2.653	2.689	EPSD	TCGA;ICGC;COSMIC	2.269	Up-regulation
TKL_RAF_RAF_BRAF_ST	Q9H9S0	NANOG	P15056	BRAF	S57	P55S	55	Missense	proximal	-2	no	2.653	2.402	EPSD	TCGA;ICGC;COSMIC	2.269	Down-regulation
TKL_RAF_RAF_BRAF_ST	Q9H9S0	NANOG	P15056	BRAF	S57	P53L	53	Missense	distal	-4	no	2.653	2.452	EPSD	TCGA;ICGC;COSMIC	2.269	Down-regulation
TKL_RAF_RAF_BRAF_ST	Q9H9S0	NANOG	P15056	BRAF	S57	L54F	54	Missense	distal	-3	no	2.653	2.478	EPSD	TCGA;ICGC;COSMIC	2.269	Down-regulation
TKL_RAF_RAF_BRAF_ST	P15056	BRAF	P15056	BRAF	T244	T241M	241	Missense	distal	-3	no	2.425	2.470	EPSD	TCGA;ICGC;COSMIC	2.269	Up-regulation
TKL_RAF_RAF_BRAF_ST	P15056	BRAF	P15056	BRAF	T244	L245F	245	Missense	proximal	1	no	2.425	2.421	EPSD	TCGA;ICGC;COSMIC	2.269	Down-regulation
TKL_RAF_RAF_BRAF_ST	P15056	BRAF	P15056	BRAF	T244	C251R	251	Missense	distal	7	no	2.425	2.462	EPSD	TCGA;ICGC;COSMIC	2.269	Up-regulation
TKL_RAF_RAF_BRAF_ST	P15056	BRAF	P15056	BRAF	S319	S317F	317	Missense	proximal	-2	no	2.010	2.277	EPSD	TCGA;ICGC;COSMIC	2.269	Gain
TKL_RAF_RAF_BRAF_ST	P15056	BRAF	P15056	BRAF	T373	P367R	367	Missense	distal	-6	no	3.959	4.005	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	2.269	Up-regulation
TKL_RAF_RAF_BRAF_ST	P15056	BRAF	P15056	BRAF	T373	D380H	380	Missense	distal	7	no	3.959	4.010	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	2.269	Up-regulation
TKL_RAF_RAF_BRAF_ST	P15056	BRAF	P15056	BRAF	T373	P367S	367	Missense	distal	-6	no	3.959	3.707	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	2.269	Down-regulation
TKL_RAF_RAF_BRAF_ST	P15056	BRAF	P15056	BRAF	T401	T401I	401	Missense	central	0	yes	2.275	0.000	EPSD	TCGA;ICGC;COSMIC	2.269	Loss
TKL_RAF_RAF_BRAF_ST	P15056	BRAF	P15056	BRAF	T401	G397S	397	Missense	distal	-4	no	2.275	2.051	EPSD	TCGA;ICGC;COSMIC	2.269	Loss
TKL_RAF_RAF_BRAF_ST	P15056	BRAF	P15056	BRAF	T401	T401A	401	Missense	central	0	yes	2.275	0.000	EPSD	TCGA;ICGC;COSMIC	2.269	Loss
TKL_RAF_RAF_BRAF_ST	P15056	BRAF	P15056	BRAF	S428	E433K	433	Missense	distal	5	no	2.410	2.259	EPSD	TCGA;ICGC;COSMIC	2.269	Loss
TKL_RAF_RAF_BRAF_ST	P15056	BRAF	P15056	BRAF	T440	E433K	433	Missense	distal	-7	no	2.323	2.312	EPSD	TCGA;ICGC;COSMIC	2.269	Down-regulation
TKL_RAF_RAF_BRAF_ST	P15056	BRAF	P15056	BRAF	S446	E451G	451	Missense	distal	5	no	2.213	2.387	EPSD	TCGA;ICGC;COSMIC	2.269	Gain
TKL_RAF_RAF_BRAF_ST	P15056	BRAF	P15056	BRAF	S614	Q609E	609	Missense	distal	-5	no	4.305	4.308	PhosphoSitePlus;EPSD	TCGA;ICGC;COSMIC	2.269	Up-regulation
TKL_RAF_RAF_BRAF_ST	P15056	BRAF	P15056	BRAF	S614	L613F	613	Missense	proximal	-1	no	4.305	4.229	PhosphoSitePlus;EPSD	TCGA;ICGC;COSMIC	2.269	Down-regulation
TKL_RAF_RAF_BRAF_ST	P15056	BRAF	P15056	BRAF	S614	Q609H	609	Missense	distal	-5	no	4.305	4.251	PhosphoSitePlus;EPSD	TCGA;ICGC;COSMIC	2.269	Down-regulation
TKL_RAF_RAF_BRAF_ST	P15056	BRAF	P15056	BRAF	S614	S614P	614	Missense	central	0	yes	4.305	0.000	PhosphoSitePlus;EPSD	TCGA;ICGC;COSMIC	2.269	Loss
TKL_RAF_RAF_BRAF_ST	Q02750	MAP2K1	P15056	BRAF	S218	V224M	224	Missense	distal	6	no	4.261	4.248	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	2.269	Down-regulation
TKL_RAF_RAF_BRAF_ST	Q02750	MAP2K1	P15056	BRAF	S222	V224M	224	Missense	proximal	2	no	4.478	4.467	PhosphoSitePlus;EPSD	TCGA;ICGC;COSMIC	2.269	Down-regulation
TKL_RAF_RAF_BRAF_ST	Q02750	MAP2K1	P15056	BRAF	S222	R227K	227	Missense	distal	5	no	4.478	4.274	PhosphoSitePlus;EPSD	TCGA;ICGC;COSMIC	2.269	Down-regulation
TKL_RAF_RAF_BRAF_ST	Q05639	EEF1A2	P15056	BRAF	S21	G25S	25	Missense	distal	4	no	4.317	4.335	PhosphoSitePlus	TCGA;ICGC	2.269	Up-regulation
TKL_RAF_RAF_BRAF_ST	Q05639	EEF1A2	P15056	BRAF	T88	K84N	84	Missense	distal	-4	no	2.933	2.831	EPSD	TCGA;ICGC;COSMIC	2.269	Down-regulation
TKL_RAF_RAF_BRAF_ST	Q05639	EEF1A2	P15056	BRAF	T88	G94R	94	Missense	distal	6	no	2.933	2.948	EPSD	TCGA;ICGC;COSMIC	2.269	Up-regulation
TKL_RAF_RAF_BRAF_ST	Q05639	EEF1A2	P15056	BRAF	T88	D91N	91	Missense	distal	3	no	2.933	2.829	EPSD	TCGA;ICGC;COSMIC	2.269	Down-regulation
TKL_RAF_RAF_BRAF_ST	Q05639	EEF1A2	P15056	BRAF	S224	G221D	221	Missense	distal	-3	no	2.268	2.399	EPSD	TCGA;ICGC;COSMIC	2.269	Gain
TKL_RAF_RAF_BRAF_ST	Q05639	EEF1A2	P15056	BRAF	S396	I401T	401	Missense	distal	5	no	2.249	2.316	EPSD	TCGA;ICGC;COSMIC	2.269	Gain
TKL_RAF_RAF_BRAF_ST	P33981	TTK	P15056	BRAF	S281	T288I	288	Missense	distal	7	no	4.020	4.050	PhosphoSitePlus;EPSD	TCGA;ICGC;COSMIC	2.269	Up-regulation
TKL_RAF_RAF_BRAF_ST	P33981	TTK	P15056	BRAF	S333	S329F	329	Missense	distal	-4	no	1.982	2.382	EPSD	TCGA;ICGC;COSMIC	2.269	Gain
TKL_RAF_RAF_BRAF_ST	P33981	TTK	P15056	BRAF	S742	I741M	741	Missense	proximal	-1	no	2.176	2.331	EPSD	TCGA;COSMIC	2.269	Gain
TKL_RAF_RAF_BRAF_ST	P33981	TTK	P15056	BRAF	S837	G839S	839	Missense	proximal	2	no	2.494	2.527	EPSD	TCGA;COSMIC	2.269	Up-regulation
TKL_RAF_RAF_BRAF_ST	P36507	MAP2K2	P15056	BRAF	S76	G83S	83	Missense	distal	7	no	2.272	1.995	EPSD	TCGA;ICGC;COSMIC	2.269	Loss
TKL_RAF_RAF_BRAF_ST	P36507	MAP2K2	P15056	BRAF	S76	E77G	77	Missense	proximal	1	no	2.272	2.276	EPSD	TCGA;ICGC;COSMIC	2.269	Up-regulation
TKL_RAF_RAF_BRAF_ST	P36507	MAP2K2	P15056	BRAF	S76	D71N	71	Missense	distal	-5	no	2.272	2.297	EPSD	TCGA;ICGC;COSMIC	2.269	Up-regulation
TKL_RAF_RAF_BRAF_ST	P36507	MAP2K2	P15056	BRAF	S76	A80V	80	Missense	distal	4	no	2.272	2.273	EPSD	TCGA;ICGC;COSMIC	2.269	Up-regulation
TKL_RAF_RAF_BRAF_ST	P36507	MAP2K2	P15056	BRAF	S222	V228M	228	Missense	distal	6	no	4.451	4.439	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	2.269	Down-regulation
TKL_RAF_RAF_BRAF_ST	P36507	MAP2K2	P15056	BRAF	S226	T230M	230	Missense	distal	4	no	4.058	4.075	PhosphoSitePlus;EPSD	TCGA;ICGC;COSMIC	2.269	Up-regulation
TKL_RAF_RAF_BRAF_ST	P36507	MAP2K2	P15056	BRAF	S226	V228M	228	Missense	proximal	2	no	4.058	4.048	PhosphoSitePlus;EPSD	TCGA;ICGC;COSMIC	2.269	Down-regulation
Other_NEK_NEK9_NEK9_ST	Q8NHV4	NEDD1	Q8TD19	NEK9	S404	S411G	411	Missense	distal	7	no	3.442	3.384	EPSD	TCGA;COSMIC	2.671	Down-regulation
Other_NEK_NEK9_NEK9_ST	Q8TDX7	NEK7	Q8TD19	NEK9	S195	S195Y	195	Missense	central	0	yes	8.327	0.000	PhosphoSitePlus	TCGA;ICGC;COSMIC	2.671	Loss
Other_NEK_NEK9_NEK9_ST	Q8TDX7	NEK7	Q8TD19	NEK9	S195	T199M	199	Missense	distal	4	no	8.327	7.905	PhosphoSitePlus	TCGA;ICGC;COSMIC	2.671	Down-regulation
Other_NEK_NEK9_NEK9_ST	Q8TD19	NEK9	Q8TD19	NEK9	S76	E82K	82	Missense	distal	6	no	3.201	3.184	EPSD	TCGA;ICGC;COSMIC	2.671	Down-regulation
Other_NEK_NEK9_NEK9_ST	Q8TD19	NEK9	Q8TD19	NEK9	S206	S206F	206	Missense	central	0	yes	2.959	0.000	EPSD	TCGA;ICGC;COSMIC	2.671	Loss
Other_NEK_NEK9_NEK9_ST	Q8TD19	NEK9	Q8TD19	NEK9	T210	S206F	206	Missense	distal	-4	no	7.795	7.836	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	2.671	Up-regulation
Other_NEK_NEK9_NEK9_ST	Q8TD19	NEK9	Q8TD19	NEK9	S331	E336Q	336	Missense	distal	5	no	4.085	4.150	EPSD	TCGA;ICGC;COSMIC	2.671	Up-regulation
Other_NEK_NEK9_NEK9_ST	Q8TD19	NEK9	Q8TD19	NEK9	S331	S332G	332	Missense	proximal	1	no	4.085	3.560	EPSD	TCGA;ICGC;COSMIC	2.671	Down-regulation
Other_NEK_NEK9_NEK9_ST	Q8TD19	NEK9	Q8TD19	NEK9	S331	R328I	328	Missense	distal	-3	no	4.085	4.030	EPSD	TCGA;ICGC;COSMIC	2.671	Down-regulation
Other_NEK_NEK9_NEK9_ST	Q8TD19	NEK9	Q8TD19	NEK9	S769	P774S	774	Missense	distal	5	no	4.072	3.100	EPSD	TCGA;ICGC;COSMIC	2.671	Down-regulation
Other_NEK_NEK9_NEK9_ST	Q8TD19	NEK9	Q8TD19	NEK9	S769	D773E	773	Missense	distal	4	no	4.072	3.966	EPSD	TCGA;ICGC;COSMIC	2.671	Down-regulation
Other_NEK_NEK9_NEK9_ST	Q8TD19	NEK9	Q8TD19	NEK9	S836	L831V	831	Missense	distal	-5	no	3.338	3.383	EPSD	TCGA;ICGC;COSMIC	2.671	Up-regulation
Other_NEK_NEK9_NEK9_ST	Q8TD19	NEK9	Q8TD19	NEK9	S836	L831F	831	Missense	distal	-5	no	3.338	3.367	EPSD	TCGA;ICGC;COSMIC	2.671	Up-regulation
Other_NEK_NEK9_NEK9_ST	Q8TD19	NEK9	Q8TD19	NEK9	S836	S829Y	829	Missense	distal	-7	no	3.338	3.361	EPSD	TCGA;ICGC;COSMIC	2.671	Up-regulation
Other_NEK_NEK9_NEK9_ST	Q8TD19	NEK9	Q8TD19	NEK9	S944	S944F	944	Missense	central	0	yes	8.113	0.000	PhosphoSitePlus;EPSD	TCGA;ICGC;COSMIC	2.671	Loss
Other_NEK_NEK9_NEK9_ST	Q8TD19	NEK9	Q8TD19	NEK9	T949	S944F	944	Missense	distal	-5	no	2.783	2.739	EPSD	TCGA;ICGC;COSMIC	2.671	Down-regulation
Other_NEK_NEK9_NEK9_ST	Q8TD19	NEK9	Q8TD19	NEK9	S964	L969R	969	Missense	distal	5	no	2.755	2.935	EPSD	TCGA;ICGC;COSMIC	2.671	Up-regulation
Other_NEK_NEK9_NEK9_ST	Q8TD19	NEK9	Q8TD19	NEK9	S966	L969R	969	Missense	distal	3	no	3.066	3.093	EPSD	TCGA;ICGC;COSMIC	2.671	Up-regulation
Other_NEK_NEK9_NEK9_ST	Q8TD19	NEK9	Q8TD19	NEK9	S978	P977L	977	Missense	proximal	-1	no	3.393	2.815	EPSD	TCGA;ICGC;COSMIC	2.671	Down-regulation
Other_NEK_NEK9_NEK9_ST	Q8TD19	NEK9	Q8TD19	NEK9	S978	P977S	977	Missense	proximal	-1	no	3.393	3.077	EPSD	TCGA;ICGC;COSMIC	2.671	Down-regulation
CAMK_MLCK_MYLK_ST	O14950	MYL12B	Q15746	MYLK	T19	R17C	17	Missense	proximal	-2	no	1.827	1.829	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	1.165	Up-regulation
CAMK_MLCK_MYLK_ST	O14950	MYL12B	Q15746	MYLK	S20	R17C	17	Missense	distal	-3	no	1.417	1.435	PhosphoSitePlus;EPSD	TCGA;ICGC;COSMIC	1.165	Up-regulation
CAMK_MLCK_MYLK_ST	O14950	MYL12B	Q15746	MYLK	T160	R161H	161	Missense	proximal	1	no	1.182	1.190	EPSD	TCGA;ICGC	1.165	Up-regulation
CAMK_MLCK_MYLK_ST	O14950	MYL12B	Q15746	MYLK	T160	E158K	158	Missense	proximal	-2	no	1.182	1.171	EPSD	TCGA;ICGC;COSMIC	1.165	Down-regulation
CAMK_MLCK_MYLK_ST	P10916	MYL2	Q15746	MYLK	S15	F18L	18	Missense	distal	3	no	1.569	1.602	PhosphoSitePlus	TCGA;ICGC	1.165	Up-regulation
CAMK_MLCK_MYLK_ST	P10916	MYL2	Q15746	MYLK	S15	G11V	11	Missense	distal	-4	no	1.569	1.556	PhosphoSitePlus	TCGA;ICGC;COSMIC	1.165	Down-regulation
CAMK_MLCK_MYLK_ST	P10916	MYL2	Q15746	MYLK	S15	G12V	12	Missense	distal	-3	no	1.569	1.547	PhosphoSitePlus	TCGA;ICGC;COSMIC	1.165	Down-regulation
CAMK_MLCK_MYLK_ST	P10916	MYL2	Q15746	MYLK	S15	A13T	13	Missense	proximal	-2	no	1.569	1.577	PhosphoSitePlus	TCGA;ICGC;COSMIC	1.165	Up-regulation
CAMK_MLCK_MYLK_ST	P10916	MYL2	Q15746	MYLK	S15	F18V	18	Missense	distal	3	no	1.569	1.572	PhosphoSitePlus	TCGA;ICGC;COSMIC	1.165	Up-regulation
CAMK_MLCK_MYLK_ST	P10916	MYL2	Q15746	MYLK	S15	E22K	22	Missense	distal	7	no	1.569	1.534	PhosphoSitePlus	TCGA;ICGC;COSMIC	1.165	Down-regulation
CAMK_MLCK_MYLK_ST	P10916	MYL2	Q15746	MYLK	T98	P95H	95	Missense	distal	-3	no	1.295	1.273	EPSD	TCGA;COSMIC	1.165	Down-regulation
CAMK_MLCK_MYLK_ST	P10916	MYL2	Q15746	MYLK	T98	P95T	95	Missense	distal	-3	no	1.295	1.304	EPSD	TCGA;COSMIC	1.165	Up-regulation
CAMK_MLCK_MYLK_ST	P10916	MYL2	Q15746	MYLK	T98	E97K	97	Missense	proximal	-1	no	1.295	1.268	EPSD	TCGA;COSMIC	1.165	Down-regulation
CAMK_MLCK_MYLK_ST	P10916	MYL2	Q15746	MYLK	T98	L100F	100	Missense	proximal	2	no	1.295	1.257	EPSD	TCGA	1.165	Down-regulation
CAMK_MLCK_MYLK_ST	P24844	MYL9	Q15746	MYLK	T19	R17W	17	Missense	proximal	-2	no	1.797	1.810	PhosphoSitePlus;EPSD	TCGA;ICGC;COSMIC	1.165	Up-regulation
CAMK_MLCK_MYLK_ST	P24844	MYL9	Q15746	MYLK	S20	R17W	17	Missense	distal	-3	no	1.446	1.502	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	1.165	Up-regulation
AGC_PKC_PKCa_PRKCG_ST	P07900	HSP90AA1	P05129	PRKCG	T5	P2L	2	Missense	distal	-3	no	96.034	98.632	EPSD	TCGA;ICGC;COSMIC	98.543	Gain
AGC_PKC_PKCa_PRKCG_ST	P07900	HSP90AA1	P05129	PRKCG	T7	P2L	2	Missense	distal	-5	no	109.654	109.643	EPSD	TCGA;ICGC;COSMIC	98.543	Down-regulation
AGC_PKC_PKCa_PRKCG_ST	P07900	HSP90AA1	P05129	PRKCG	T425	E429K	429	Missense	distal	4	no	113.801	118.284	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	98.543	Up-regulation
AGC_PKC_PKCa_PRKCG_ST	P07900	HSP90AA1	P05129	PRKCG	S476	D472H	472	Missense	distal	-4	no	112.123	111.069	EPSD	TCGA;COSMIC	98.543	Down-regulation
AGC_PKC_PKCa_PRKCG_ST	Q9H3Z4	DNAJC5	P05129	PRKCG	S8	R5K	5	Missense	distal	-3	no	133.135	131.570	EPSD	TCGA;ICGC;COSMIC	98.543	Down-regulation
AGC_PKC_PKCa_PRKCG_ST	Q9H3Z4	DNAJC5	P05129	PRKCG	S8	R7H	7	Missense	proximal	-1	no	133.135	129.704	EPSD	TCGA;ICGC;COSMIC	98.543	Down-regulation
AGC_PKC_PKCa_PRKCG_ST	Q9H3Z4	DNAJC5	P05129	PRKCG	S8	D3H	3	Missense	distal	-5	no	133.135	135.212	EPSD	TCGA;ICGC;COSMIC	98.543	Up-regulation
AGC_PKC_PKCa_PRKCG_ST	Q9H3Z4	DNAJC5	P05129	PRKCG	S10	R5K	5	Missense	distal	-5	no	128.222	128.328	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	98.543	Up-regulation
AGC_PKC_PKCa_PRKCG_ST	Q9H3Z4	DNAJC5	P05129	PRKCG	S10	R7H	7	Missense	distal	-3	no	128.222	125.464	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	98.543	Down-regulation
AGC_PKC_PKCa_PRKCG_ST	Q9H3Z4	DNAJC5	P05129	PRKCG	S10	D3H	3	Missense	distal	-7	no	128.222	128.070	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	98.543	Down-regulation
AGC_PKC_PKCa_PRKCG_ST	Q9H3Z4	DNAJC5	P05129	PRKCG	T11	R5K	5	Missense	distal	-6	no	108.632	107.206	EPSD	TCGA;ICGC;COSMIC	98.543	Down-regulation
AGC_PKC_PKCa_PRKCG_ST	Q9H3Z4	DNAJC5	P05129	PRKCG	T11	R7H	7	Missense	distal	-4	no	108.632	107.632	EPSD	TCGA;ICGC;COSMIC	98.543	Down-regulation
AGC_PKC_PKCa_PRKCG_ST	Q9H3Z4	DNAJC5	P05129	PRKCG	S34	L38F	38	Missense	distal	4	no	135.866	142.891	PhosphoSitePlus;EPSD	TCGA;ICGC;COSMIC	98.543	Up-regulation
AGC_PKC_PKCa_PRKCG_ST	Q9H3Z4	DNAJC5	P05129	PRKCG	S34	R36W	36	Missense	proximal	2	no	135.866	105.412	PhosphoSitePlus;EPSD	TCGA;ICGC;COSMIC	98.543	Down-regulation
AGC_PKC_PKCa_PRKCG_ST	Q9H3Z4	DNAJC5	P05129	PRKCG	T146	E142K	142	Missense	distal	-4	no	107.427	109.005	EPSD	TCGA;ICGC;COSMIC	98.543	Up-regulation
AGC_PKC_PKCa_PRKCG_ST	Q9H3Z4	DNAJC5	P05129	PRKCG	T146	P152L	152	Missense	distal	6	no	107.427	104.545	EPSD	TCGA;ICGC;COSMIC	98.543	Down-regulation
AGC_PKC_PKCa_PRKCG_ST	P10636	MAPT	P05129	PRKCG	S341	E348V	348	Missense	distal	7	no	119.427	113.410	EPSD	TCGA;ICGC;COSMIC	98.543	Down-regulation
AGC_PKC_PKCa_PRKCG_ST	P10636	MAPT	P05129	PRKCG	S341	G339R	339	Missense	proximal	-2	no	119.427	128.000	EPSD	TCGA;ICGC;COSMIC	98.543	Up-regulation
AGC_PKC_PKCa_PRKCG_ST	P10636	MAPT	P05129	PRKCG	S341	S341F	341	Missense	central	0	yes	119.427	0.000	EPSD	TCGA;ICGC;COSMIC	98.543	Loss
AGC_PKC_PKCa_PRKCG_ST	P10636	MAPT	P05129	PRKCG	S355	E348V	348	Missense	distal	-7	no	100.712	98.687	EPSD	TCGA;ICGC;COSMIC	98.543	Down-regulation
AGC_PKC_PKCa_PRKCG_ST	P10636	MAPT	P05129	PRKCG	S355	D350G	350	Missense	distal	-5	no	100.712	102.893	EPSD	TCGA;ICGC;COSMIC	98.543	Up-regulation
AGC_PKC_PKCa_PRKCG_ST	P10636	MAPT	P05129	PRKCG	S451	E456K	456	Missense	distal	5	no	89.544	101.489	EPSD	TCGA;ICGC;COSMIC	98.543	Gain
AGC_PKC_PKCa_PRKCG_ST	P98082	DAB2	P05129	PRKCG	S2	S2F	2	Missense	central	0	yes	101.006	0.000	EPSD	TCGA;ICGC;COSMIC	98.543	Loss
AGC_PKC_PKCa_PRKCG_ST	P98082	DAB2	P05129	PRKCG	T7	S2F	2	Missense	distal	-5	no	101.563	101.562	EPSD	TCGA;ICGC;COSMIC	98.543	Down-regulation
AGC_PKC_PKCa_PRKCG_ST	P98082	DAB2	P05129	PRKCG	T7	Q13H	13	Missense	distal	6	no	101.563	99.979	EPSD	TCGA;ICGC;COSMIC	98.543	Down-regulation
AGC_PKC_PKCa_PRKCG_ST	P98082	DAB2	P05129	PRKCG	T7	Q13L	13	Missense	distal	6	no	101.563	98.896	EPSD	TCGA;ICGC;COSMIC	98.543	Down-regulation
AGC_PKC_PKCa_PRKCG_ST	P98082	DAB2	P05129	PRKCG	S8	S2F	2	Missense	distal	-6	no	120.522	123.356	EPSD	TCGA;ICGC;COSMIC	98.543	Up-regulation
AGC_PKC_PKCa_PRKCG_ST	P98082	DAB2	P05129	PRKCG	S8	Q13H	13	Missense	distal	5	no	120.522	109.922	EPSD	TCGA;ICGC;COSMIC	98.543	Down-regulation
AGC_PKC_PKCa_PRKCG_ST	P98082	DAB2	P05129	PRKCG	S8	Q13L	13	Missense	distal	5	no	120.522	111.404	EPSD	TCGA;ICGC;COSMIC	98.543	Down-regulation
AGC_PKC_PKCa_PRKCG_ST	P98082	DAB2	P05129	PRKCG	T10	Q13H	13	Missense	distal	3	no	106.074	114.919	EPSD	TCGA;ICGC;COSMIC	98.543	Up-regulation
AGC_PKC_PKCa_PRKCG_ST	P98082	DAB2	P05129	PRKCG	T10	Q13L	13	Missense	distal	3	no	106.074	111.737	EPSD	TCGA;ICGC;COSMIC	98.543	Up-regulation
AGC_PKC_PKCa_PRKCG_ST	P98082	DAB2	P05129	PRKCG	S24	K21E	21	Missense	distal	-3	no	142.045	131.181	PhosphoSitePlus	TCGA;ICGC;COSMIC	98.543	Down-regulation
AGC_PKC_PKCa_PRKCG_ST	P98082	DAB2	P05129	PRKCG	S24	A18G	18	Missense	distal	-6	no	142.045	139.382	PhosphoSitePlus	TCGA;ICGC;COSMIC	98.543	Down-regulation
AGC_PKC_PKCa_PRKCG_ST	P98082	DAB2	P05129	PRKCG	S24	A22T	22	Missense	proximal	-2	no	142.045	149.071	PhosphoSitePlus	TCGA;ICGC;COSMIC	98.543	Up-regulation
AGC_PKC_PKCa_PRKCG_ST	P98082	DAB2	P05129	PRKCG	S24	A18V	18	Missense	distal	-6	no	142.045	136.933	PhosphoSitePlus	TCGA;ICGC;COSMIC	98.543	Down-regulation
AGC_PKC_PKCa_PRKCG_ST	P98082	DAB2	P05129	PRKCG	S24	K29N	29	Missense	distal	5	no	142.045	132.775	PhosphoSitePlus	TCGA;ICGC;COSMIC	98.543	Down-regulation
AGC_PKC_PKCa_PRKCG_ST	P98082	DAB2	P05129	PRKCG	S249	L250S	250	Missense	proximal	1	no	101.481	89.862	EPSD	TCGA;ICGC	98.543	Loss
AGC_PKC_PKCa_PRKCG_ST	P98082	DAB2	P05129	PRKCG	S249	D244N	244	Missense	distal	-5	no	101.481	102.168	EPSD	TCGA;ICGC;COSMIC	98.543	Up-regulation
AGC_PKC_PKCa_PRKCG_ST	P98082	DAB2	P05129	PRKCG	S249	E242G	242	Missense	distal	-7	no	101.481	102.103	EPSD	TCGA	98.543	Up-regulation
AGC_PKC_PKCa_PRKCG_ST	P98082	DAB2	P05129	PRKCG	S313	S316Y	316	Missense	distal	3	no	90.321	100.122	EPSD	TCGA;ICGC	98.543	Gain
AGC_PKC_PKCa_PRKCG_ST	P98082	DAB2	P05129	PRKCG	S327	G334E	334	Missense	distal	7	no	92.131	99.015	EPSD	TCGA;ICGC;COSMIC	98.543	Gain
AGC_PKC_PKCa_PRKCG_ST	P98082	DAB2	P05129	PRKCG	S401	P402L	402	Missense	proximal	1	no	94.591	108.725	EPSD	TCGA;ICGC;COSMIC	98.543	Gain
AGC_PKC_PKCa_PRKCG_ST	P98082	DAB2	P05129	PRKCG	S436	R441T	441	Missense	distal	5	no	100.881	100.095	EPSD	TCGA;ICGC;COSMIC	98.543	Down-regulation
AGC_PKC_PKCa_PRKCG_ST	P98082	DAB2	P05129	PRKCG	S436	Q435E	435	Missense	proximal	-1	no	100.881	101.488	EPSD	TCGA;COSMIC	98.543	Up-regulation
AGC_PKC_PKCa_PRKCG_ST	P98082	DAB2	P05129	PRKCG	S676	E672K	672	Missense	distal	-4	no	103.739	105.318	EPSD	TCGA;COSMIC	98.543	Up-regulation
AGC_PKC_PKCa_PRKCG_ST	P98082	DAB2	P05129	PRKCG	S676	R669Q	669	Missense	distal	-7	no	103.739	104.926	EPSD	TCGA;COSMIC	98.543	Up-regulation
AGC_PKC_PKCa_PRKCG_ST	P98082	DAB2	P05129	PRKCG	S676	G671V	671	Missense	distal	-5	no	103.739	106.302	EPSD	TCGA	98.543	Up-regulation
AGC_PKC_PKCa_PRKCG_ST	P98082	DAB2	P05129	PRKCG	S676	A683V	683	Missense	distal	7	no	103.739	96.694	EPSD	TCGA;COSMIC	98.543	Loss
AGC_PKC_PKCa_PRKCG_ST	P98082	DAB2	P05129	PRKCG	S688	A683V	683	Missense	distal	-5	no	109.302	113.192	EPSD	TCGA;COSMIC	98.543	Up-regulation
AGC_PKC_PKCa_PRKCG_ST	P98082	DAB2	P05129	PRKCG	S723	P725R	725	Missense	proximal	2	no	86.798	108.909	EPSD	TCGA;COSMIC	98.543	Gain
AGC_PKC_PKCa_PRKCG_ST	Q03721	KCNC4	P05129	PRKCG	S21	E27Q	27	Missense	distal	6	no	135.397	133.532	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	98.543	Down-regulation
AGC_PKC_PKCa_PRKCG_ST	Q03721	KCNC4	P05129	PRKCG	S21	E28V	28	Missense	distal	7	no	135.397	129.380	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	98.543	Down-regulation
AGC_PKC_PKCa_PRKCG_ST	Q03721	KCNC4	P05129	PRKCG	T49	G44S	44	Missense	distal	-5	no	109.119	106.002	EPSD	TCGA;ICGC;COSMIC	98.543	Down-regulation
AGC_PKC_PKCa_PRKCG_ST	Q03721	KCNC4	P05129	PRKCG	T49	S52N	52	Missense	distal	3	no	109.119	123.248	EPSD	TCGA;ICGC;COSMIC	98.543	Up-regulation
AGC_PKC_PKCa_PRKCG_ST	Q03721	KCNC4	P05129	PRKCG	T49	E48D	48	Missense	proximal	-1	no	109.119	113.590	EPSD	TCGA;ICGC;COSMIC	98.543	Up-regulation
AGC_PKC_PKCa_PRKCG_ST	Q03721	KCNC4	P05129	PRKCG	T49	R46Q	46	Missense	distal	-3	no	109.119	101.666	EPSD	TCGA;ICGC;COSMIC;CCLE	98.543	Down-regulation
AGC_PKC_PKCa_PRKCG_ST	Q03721	KCNC4	P05129	PRKCG	T578	A573T	573	Missense	distal	-5	no	118.699	117.569	EPSD	TCGA;ICGC;COSMIC	98.543	Down-regulation
AGC_PKC_PKCa_PRKCG_ST	Q03721	KCNC4	P05129	PRKCG	T578	R575L	575	Missense	distal	-3	no	118.699	109.182	EPSD	TCGA;ICGC;COSMIC	98.543	Down-regulation
AGC_PKC_PKCa_PRKCG_ST	Q03721	KCNC4	P05129	PRKCG	T578	R572Q	572	Missense	distal	-6	no	118.699	115.234	EPSD	TCGA;ICGC;COSMIC	98.543	Down-regulation
AGC_PKC_PKCa_PRKCG_ST	Q03721	KCNC4	P05129	PRKCG	T578	R576C	576	Missense	proximal	-2	no	118.699	108.506	EPSD	TCGA;ICGC;COSMIC	98.543	Down-regulation
AGC_PKC_PKCa_PRKCG_ST	Q03721	KCNC4	P05129	PRKCG	T578	R576L	576	Missense	proximal	-2	no	118.699	112.222	EPSD	TCGA;ICGC;COSMIC	98.543	Down-regulation
AGC_PKC_PKCa_PRKCG_ST	P43629	KIR3DL1	P05129	PRKCG	S225	P230L	230	Missense	distal	5	no	104.033	102.307	EPSD	TCGA;ICGC;COSMIC	98.543	Down-regulation
AGC_PKC_PKCa_PRKCG_ST	P43629	KIR3DL1	P05129	PRKCG	S225	S227L	227	Missense	proximal	2	no	104.033	106.166	EPSD	TCGA;ICGC;COSMIC	98.543	Up-regulation
AGC_PKC_PKCa_PRKCG_ST	P43629	KIR3DL1	P05129	PRKCG	S225	S225F	225	Missense	central	0	yes	104.033	0.000	EPSD	TCGA;ICGC;COSMIC	98.543	Loss
AGC_PKC_PKCa_PRKCG_ST	P43629	KIR3DL1	P05129	PRKCG	S225	G231S	231	Missense	distal	6	no	104.033	99.701	EPSD	TCGA;ICGC;COSMIC	98.543	Down-regulation
AGC_PKC_PKCa_PRKCG_ST	P43629	KIR3DL1	P05129	PRKCG	S225	P220S	220	Missense	distal	-5	no	104.033	100.775	EPSD	TCGA;ICGC;COSMIC	98.543	Down-regulation
AGC_PKC_PKCa_PRKCG_ST	P43629	KIR3DL1	P05129	PRKCG	S415	R413C	413	Missense	proximal	-2	no	129.110	118.917	PhosphoSitePlus	TCGA;ICGC;COSMIC	98.543	Down-regulation
AGC_PKC_PKCa_PRKCG_ST	P43629	KIR3DL1	P05129	PRKCG	S415	P421H	421	Missense	distal	6	no	129.110	127.312	PhosphoSitePlus	TCGA;COSMIC	98.543	Down-regulation
AGC_PKC_PKCa_PRKCG_ST	P43629	KIR3DL1	P05129	PRKCG	S415	Q408K	408	Missense	distal	-7	no	129.110	129.170	PhosphoSitePlus	TCGA;COSMIC	98.543	Up-regulation
AGC_PKC_PKCa_PRKCG_ST	P43629	KIR3DL1	P05129	PRKCG	S415	R413H	413	Missense	proximal	-2	no	129.110	126.382	PhosphoSitePlus	TCGA;COSMIC	98.543	Down-regulation
AGC_PKC_PKCa_PRKCG_ST	P43629	KIR3DL1	P05129	PRKCG	S415	T412S	412	Missense	distal	-3	no	129.110	124.788	PhosphoSitePlus	TCGA;COSMIC	98.543	Down-regulation
AGC_PKC_PKCa_PRKCG_ST	P43629	KIR3DL1	P05129	PRKCG	S415	P418H	418	Missense	distal	3	no	129.110	134.120	PhosphoSitePlus	TCGA;COSMIC	98.543	Up-regulation
AGC_PKC_PKCa_PRKCG_ST	P49841	GSK3B	P05129	PRKCG	S13	Q19R	19	Missense	distal	6	no	109.051	110.642	EPSD	TCGA	98.543	Up-regulation
AGC_PKC_PKCa_PRKCG_ST	P49841	GSK3B	P05129	PRKCG	S21	Q19R	19	Missense	proximal	-2	no	118.678	127.066	EPSD	TCGA	98.543	Up-regulation
AGC_PKC_PKCa_PRKCG_ST	P49841	GSK3B	P05129	PRKCG	S21	S25N	25	Missense	distal	4	no	118.678	122.530	EPSD	TCGA;ICGC	98.543	Up-regulation
AGC_PKC_PKCa_PRKCG_ST	P49841	GSK3B	P05129	PRKCG	S21	A22S	22	Missense	proximal	1	no	118.678	116.446	EPSD	TCGA;ICGC	98.543	Down-regulation
AGC_PKC_PKCa_PRKCG_ST	P49841	GSK3B	P05129	PRKCG	S35	G34S	34	Missense	proximal	-1	no	104.123	107.961	EPSD	TCGA;COSMIC	98.543	Up-regulation
AGC_PKC_PKCa_PRKCG_ST	P49841	GSK3B	P05129	PRKCG	S66	T59I	59	Missense	distal	-7	no	98.842	94.204	EPSD	TCGA;ICGC;COSMIC	98.543	Loss
AGC_PKC_PKCa_PRKCG_ST	P49841	GSK3B	P05129	PRKCG	S66	G68V	68	Missense	proximal	2	no	98.842	109.225	EPSD	TCGA;ICGC;COSMIC	98.543	Up-regulation
AGC_PKC_PKCa_PRKCG_ST	Q9UBS0	RPS6KB2	P05129	PRKCG	S410	S410L	410	Missense	central	0	yes	110.155	0.000	EPSD	TCGA;ICGC;COSMIC	98.543	Loss
AGC_PKC_PKCa_PRKCG_ST	Q9UBS0	RPS6KB2	P05129	PRKCG	S416	R419W	419	Missense	distal	3	no	98.869	94.872	EPSD	TCGA;ICGC;COSMIC	98.543	Loss
AGC_PKC_PKCa_PRKCG_ST	Q9UBS0	RPS6KB2	P05129	PRKCG	S416	S410L	410	Missense	distal	-6	no	98.869	98.065	EPSD	TCGA;ICGC;COSMIC	98.543	Loss
AGC_PKC_PKCa_PRKCG_ST	Q9UBS0	RPS6KB2	P05129	PRKCG	S436	P440L	440	Missense	distal	4	no	98.543	96.930	EPSD	TCGA;ICGC;COSMIC;GDSC	98.543	Loss
AGC_PKC_PKCa_PRKCG_ST	Q9UBS0	RPS6KB2	P05129	PRKCG	S438	P440L	440	Missense	proximal	2	no	95.351	98.900	EPSD	TCGA;ICGC;COSMIC;GDSC	98.543	Gain
AGC_PKC_PKCa_PRKCG_ST	Q14155	ARHGEF7	P05129	PRKCG	S19	T23P	23	Missense	distal	4	no	103.720	103.329	EPSD	TCGA;ICGC;COSMIC	98.543	Down-regulation
AGC_PKC_PKCa_PRKCG_ST	Q14155	ARHGEF7	P05129	PRKCG	S19	T23N	23	Missense	distal	4	no	103.720	107.501	EPSD	TCGA;ICGC;COSMIC;GDSC;CCLE	98.543	Up-regulation
AGC_PKC_PKCa_PRKCG_ST	Q14155	ARHGEF7	P05129	PRKCG	S19	I24V	24	Missense	distal	5	no	103.720	104.830	EPSD	TCGA;ICGC;COSMIC	98.543	Up-regulation
AGC_PKC_PKCa_PRKCG_ST	Q14155	ARHGEF7	P05129	PRKCG	T23	T23P	23	Missense	central	0	yes	122.016	0.000	EPSD	TCGA;ICGC;COSMIC	98.543	Loss
AGC_PKC_PKCa_PRKCG_ST	Q14155	ARHGEF7	P05129	PRKCG	T23	T23N	23	Missense	central	0	yes	122.016	0.000	EPSD	TCGA;ICGC;COSMIC;GDSC;CCLE	98.543	Loss
AGC_PKC_PKCa_PRKCG_ST	Q14155	ARHGEF7	P05129	PRKCG	T23	I24V	24	Missense	proximal	1	no	122.016	117.832	EPSD	TCGA;ICGC;COSMIC	98.543	Down-regulation
AGC_PKC_PKCa_PRKCG_ST	Q14155	ARHGEF7	P05129	PRKCG	S148	V142M	142	Missense	distal	-6	no	97.709	99.317	EPSD	TCGA;ICGC;COSMIC	98.543	Gain
AGC_PKC_PKCa_PRKCG_ST	Q14155	ARHGEF7	P05129	PRKCG	S244	R239H	239	Missense	distal	-5	no	99.404	101.980	EPSD	TCGA;ICGC;COSMIC	98.543	Up-regulation
AGC_PKC_PKCa_PRKCG_ST	Q14155	ARHGEF7	P05129	PRKCG	S244	K251N	251	Missense	distal	7	no	99.404	105.204	EPSD	TCGA;ICGC;COSMIC	98.543	Up-regulation
AGC_PKC_PKCa_PRKCG_ST	Q14155	ARHGEF7	P05129	PRKCG	S244	R239C	239	Missense	distal	-5	no	99.404	106.072	EPSD	TCGA;ICGC;COSMIC	98.543	Up-regulation
AGC_PKC_PKCa_PRKCG_ST	Q14155	ARHGEF7	P05129	PRKCG	T254	K251N	251	Missense	distal	-3	no	111.855	99.558	EPSD	TCGA;ICGC;COSMIC	98.543	Down-regulation
AGC_PKC_PKCa_PRKCG_ST	Q14155	ARHGEF7	P05129	PRKCG	S295	Y297H	297	Missense	proximal	2	no	100.873	101.818	EPSD	TCGA;ICGC	98.543	Up-regulation
AGC_PKC_PKCa_PRKCG_ST	Q14155	ARHGEF7	P05129	PRKCG	S518	G519D	519	Missense	proximal	1	no	122.299	120.052	PhosphoSitePlus;EPSD	TCGA;COSMIC	98.543	Down-regulation
AGC_PKC_PKCa_PRKCG_ST	Q14155	ARHGEF7	P05129	PRKCG	S518	G519V	519	Missense	proximal	1	no	122.299	125.034	PhosphoSitePlus;EPSD	TCGA	98.543	Up-regulation
AGC_PKC_PKCa_PRKCG_ST	Q14155	ARHGEF7	P05129	PRKCG	S581	P585S	585	Missense	distal	4	no	110.016	110.336	EPSD	TCGA;ICGC;COSMIC	98.543	Up-regulation
AGC_PKC_PKCa_PRKCG_ST	Q14155	ARHGEF7	P05129	PRKCG	S581	T580M	580	Missense	proximal	-1	no	110.016	111.511	EPSD	TCGA;ICGC;COSMIC	98.543	Up-regulation
AGC_PKC_PKCa_PRKCG_ST	Q14155	ARHGEF7	P05129	PRKCG	S581	G583R	583	Missense	proximal	2	no	110.016	131.662	EPSD	TCGA;ICGC;COSMIC	98.543	Up-regulation
AGC_PKC_PKCa_PRKCG_ST	Q14155	ARHGEF7	P05129	PRKCG	S581	V579I	579	Missense	proximal	-2	no	110.016	97.144	EPSD	TCGA;ICGC;COSMIC	98.543	Loss
AGC_PKC_PKCa_PRKCG_ST	Q14155	ARHGEF7	P05129	PRKCG	S605	A609T	609	Missense	distal	4	no	104.992	103.763	EPSD	TCGA;ICGC;COSMIC;CCLE	98.543	Down-regulation
AGC_PKC_PKCa_PRKCG_ST	Q14155	ARHGEF7	P05129	PRKCG	S605	D610Y	610	Missense	distal	5	no	104.992	106.685	EPSD	TCGA;ICGC	98.543	Up-regulation
AGC_PKC_PKCa_PRKCG_ST	Q14155	ARHGEF7	P05129	PRKCG	S674	K675R	675	Missense	proximal	1	no	103.244	100.329	EPSD	TCGA;ICGC;COSMIC	98.543	Down-regulation
AGC_PKC_PKCa_PRKCG_ST	Q14155	ARHGEF7	P05129	PRKCG	S674	S676I	676	Missense	proximal	2	no	103.244	103.319	EPSD	TCGA;ICGC;COSMIC	98.543	Up-regulation
AGC_PKC_PKCa_PRKCG_ST	Q14155	ARHGEF7	P05129	PRKCG	S674	P677H	677	Missense	distal	3	no	103.244	108.255	EPSD	TCGA;ICGC;COSMIC	98.543	Up-regulation
AGC_PKC_PKCa_PRKCG_ST	Q14155	ARHGEF7	P05129	PRKCG	S674	K678E	678	Missense	distal	4	no	103.244	98.762	EPSD	TCGA;ICGC;COSMIC	98.543	Down-regulation
AGC_PKC_PKCa_PRKCG_ST	Q14155	ARHGEF7	P05129	PRKCG	S676	K675R	675	Missense	proximal	-1	no	102.368	102.400	EPSD	TCGA;ICGC;COSMIC	98.543	Up-regulation
AGC_PKC_PKCa_PRKCG_ST	Q14155	ARHGEF7	P05129	PRKCG	S676	S676I	676	Missense	central	0	yes	102.368	0.000	EPSD	TCGA;ICGC;COSMIC	98.543	Loss
AGC_PKC_PKCa_PRKCG_ST	Q14155	ARHGEF7	P05129	PRKCG	S676	P677H	677	Missense	proximal	1	no	102.368	112.873	EPSD	TCGA;ICGC;COSMIC	98.543	Up-regulation
AGC_PKC_PKCa_PRKCG_ST	Q14155	ARHGEF7	P05129	PRKCG	S676	K678E	678	Missense	proximal	2	no	102.368	70.416	EPSD	TCGA;ICGC;COSMIC	98.543	Loss
AGC_PKC_PKCa_PRKCG_ST	Q14155	ARHGEF7	P05129	PRKCG	T679	K675R	675	Missense	distal	-4	no	105.583	105.209	EPSD	TCGA;ICGC;COSMIC	98.543	Down-regulation
AGC_PKC_PKCa_PRKCG_ST	Q14155	ARHGEF7	P05129	PRKCG	T679	S676I	676	Missense	distal	-3	no	105.583	99.422	EPSD	TCGA;ICGC;COSMIC	98.543	Down-regulation
AGC_PKC_PKCa_PRKCG_ST	Q14155	ARHGEF7	P05129	PRKCG	T679	P677H	677	Missense	proximal	-2	no	105.583	116.466	EPSD	TCGA;ICGC;COSMIC	98.543	Up-regulation
AGC_PKC_PKCa_PRKCG_ST	Q14155	ARHGEF7	P05129	PRKCG	T679	K678E	678	Missense	proximal	-1	no	105.583	103.676	EPSD	TCGA;ICGC;COSMIC	98.543	Down-regulation
AGC_PKC_PKCa_PRKCG_ST	Q14155	ARHGEF7	P05129	PRKCG	S723	A724T	724	Missense	proximal	1	no	99.724	100.604	EPSD	TCGA;ICGC;COSMIC	98.543	Up-regulation
AGC_PKC_PKCa_PRKCG_ST	Q14155	ARHGEF7	P05129	PRKCG	S723	T726A	726	Missense	distal	3	no	99.724	100.290	EPSD	TCGA;ICGC	98.543	Up-regulation
AGC_PKC_PKCa_PRKCG_ST	Q14155	ARHGEF7	P05129	PRKCG	S761	D754Y	754	Missense	distal	-7	no	124.385	121.618	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	98.543	Down-regulation
AGC_PKC_PKCa_PRKCG_ST	Q14155	ARHGEF7	P05129	PRKCG	S761	R759H	759	Missense	proximal	-2	no	124.385	121.658	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC;GDSC;CCLE	98.543	Down-regulation
AGC_PKC_PKCa_PRKCG_ST	P21730	C5AR1	P05129	PRKCG	S314	G309D	309	Missense	distal	-5	no	108.132	105.952	EPSD	TCGA;ICGC;COSMIC	98.543	Down-regulation
AGC_PKC_PKCa_PRKCG_ST	P21730	C5AR1	P05129	PRKCG	S314	S314F	314	Missense	central	0	yes	108.132	0.000	EPSD	TCGA;ICGC;COSMIC	98.543	Loss
AGC_PKC_PKCa_PRKCG_ST	P21730	C5AR1	P05129	PRKCG	S314	P316S	316	Missense	proximal	2	no	108.132	109.548	EPSD	TCGA;ICGC;COSMIC;GDSC;CCLE	98.543	Up-regulation
AGC_PKC_PKCa_PRKCG_ST	P21730	C5AR1	P05129	PRKCG	S314	R320Q	320	Missense	distal	6	no	108.132	106.541	EPSD	TCGA;ICGC;COSMIC	98.543	Down-regulation
AGC_PKC_PKCa_PRKCG_ST	P21730	C5AR1	P05129	PRKCG	S314	L315I	315	Missense	proximal	1	no	108.132	104.479	EPSD	TCGA;ICGC;COSMIC	98.543	Down-regulation
AGC_PKC_PKCa_PRKCG_ST	P21730	C5AR1	P05129	PRKCG	S317	S314F	314	Missense	distal	-3	no	98.724	101.009	EPSD	TCGA;ICGC;COSMIC	98.543	Up-regulation
AGC_PKC_PKCa_PRKCG_ST	P21730	C5AR1	P05129	PRKCG	S317	P316S	316	Missense	proximal	-1	no	98.724	103.790	EPSD	TCGA;ICGC;COSMIC;GDSC;CCLE	98.543	Up-regulation
AGC_PKC_PKCa_PRKCG_ST	P21730	C5AR1	P05129	PRKCG	S317	R320Q	320	Missense	distal	3	no	98.724	89.530	EPSD	TCGA;ICGC;COSMIC	98.543	Loss
AGC_PKC_PKCa_PRKCG_ST	P21730	C5AR1	P05129	PRKCG	S317	L315I	315	Missense	proximal	-2	no	98.724	86.606	EPSD	TCGA;ICGC;COSMIC	98.543	Loss
AGC_PKC_PKCa_PRKCG_ST	P21730	C5AR1	P05129	PRKCG	S327	R320Q	320	Missense	distal	-7	no	106.879	108.065	EPSD	TCGA;ICGC;COSMIC	98.543	Up-regulation
AGC_PKC_PKCa_PRKCG_ST	P21730	C5AR1	P05129	PRKCG	S334	S338Y	338	Missense	distal	4	no	102.791	104.373	PhosphoSitePlus	TCGA;ICGC;COSMIC	98.543	Up-regulation
AGC_PKC_PKCa_PRKCG_ST	P06127	CD5	P05129	PRKCG	S309	V315E	315	Missense	distal	6	no	101.124	105.120	EPSD	TCGA;ICGC;COSMIC	98.543	Up-regulation
AGC_PKC_PKCa_PRKCG_ST	P06127	CD5	P05129	PRKCG	S309	E313K	313	Missense	distal	4	no	101.124	105.606	EPSD	TCGA;ICGC;COSMIC	98.543	Up-regulation
AGC_PKC_PKCa_PRKCG_ST	P06127	CD5	P05129	PRKCG	S309	W312L	312	Missense	distal	3	no	101.124	101.590	EPSD	TCGA;ICGC	98.543	Up-regulation
AGC_PKC_PKCa_PRKCG_ST	P06127	CD5	P05129	PRKCG	T434	M427T	427	Missense	distal	-7	no	123.839	126.159	PhosphoSitePlus;EPSD	TCGA;ICGC	98.543	Up-regulation
AGC_PKC_PKCa_PRKCG_ST	P06127	CD5	P05129	PRKCG	T434	F429L	429	Missense	distal	-5	no	123.839	127.087	PhosphoSitePlus;EPSD	TCGA;ICGC	98.543	Up-regulation
AGC_PKC_PKCa_PRKCG_ST	P06127	CD5	P05129	PRKCG	T434	R438Q	438	Missense	distal	4	no	123.839	123.020	PhosphoSitePlus;EPSD	TCGA;ICGC;COSMIC	98.543	Down-regulation
AGC_PKC_PKCa_PRKCG_ST	P06127	CD5	P05129	PRKCG	T436	N443S	443	Missense	distal	7	no	119.055	105.816	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	98.543	Down-regulation
AGC_PKC_PKCa_PRKCG_ST	P06127	CD5	P05129	PRKCG	T436	F429L	429	Missense	distal	-7	no	119.055	118.598	EPSD;PhosphoSitePlus	TCGA;ICGC	98.543	Down-regulation
AGC_PKC_PKCa_PRKCG_ST	P06127	CD5	P05129	PRKCG	T436	R438Q	438	Missense	proximal	2	no	119.055	88.898	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	98.543	Loss
AGC_PKC_PKCa_PRKCG_ST	P06127	CD5	P05129	PRKCG	S476	Q478H	478	Missense	proximal	2	no	95.356	99.737	EPSD	TCGA;ICGC;COSMIC	98.543	Gain
AGC_PKC_PKCa_PRKCG_ST	P06127	CD5	P05129	PRKCG	S476	S483F	483	Missense	distal	7	no	95.356	101.121	EPSD	TCGA;ICGC;COSMIC	98.543	Gain
AGC_PKC_PKCa_PRKCG_ST	P28329	CHAT	P05129	PRKCG	T373	D379Y	379	Missense	distal	6	no	125.078	123.980	EPSD	TCGA;COSMIC	98.543	Down-regulation
AGC_PKC_PKCa_PRKCG_ST	P28329	CHAT	P05129	PRKCG	T373	S377L	377	Missense	distal	4	no	125.078	123.145	EPSD	TCGA;COSMIC	98.543	Down-regulation
AGC_PKC_PKCa_PRKCG_ST	P28329	CHAT	P05129	PRKCG	S464	H460L	460	Missense	distal	-4	no	131.934	132.165	EPSD	TCGA;COSMIC	98.543	Up-regulation
AGC_PKC_PKCa_PRKCG_ST	P28329	CHAT	P05129	PRKCG	S464	L457M	457	Missense	distal	-7	no	131.934	131.313	EPSD	TCGA;COSMIC	98.543	Down-regulation
AGC_PKC_PKCa_PRKCG_ST	P28329	CHAT	P05129	PRKCG	S464	R470Q	470	Missense	distal	6	no	131.934	130.343	EPSD	TCGA;COSMIC	98.543	Down-regulation
AGC_PKC_PKCa_PRKCG_ST	P28329	CHAT	P05129	PRKCG	S464	R466K	466	Missense	proximal	2	no	131.934	127.464	EPSD	TCGA;COSMIC	98.543	Down-regulation
AGC_PKC_PKCa_PRKCG_ST	P28329	CHAT	P05129	PRKCG	S465	H460L	460	Missense	distal	-5	no	123.224	123.458	EPSD	TCGA;COSMIC	98.543	Up-regulation
AGC_PKC_PKCa_PRKCG_ST	P28329	CHAT	P05129	PRKCG	S465	R470Q	470	Missense	distal	5	no	123.224	128.111	EPSD	TCGA;COSMIC	98.543	Up-regulation
AGC_PKC_PKCa_PRKCG_ST	P28329	CHAT	P05129	PRKCG	S465	R466K	466	Missense	proximal	1	no	123.224	126.139	EPSD	TCGA;COSMIC	98.543	Up-regulation
AGC_PKC_PKCa_PRKCG_ST	P28329	CHAT	P05129	PRKCG	S558	A557V	557	Missense	proximal	-1	no	134.661	127.478	EPSD	TCGA;COSMIC	98.543	Down-regulation
AGC_PKC_PKCa_PRKCG_ST	P28329	CHAT	P05129	PRKCG	S558	P552L	552	Missense	distal	-6	no	134.661	133.158	EPSD	TCGA;COSMIC	98.543	Down-regulation
AGC_PKC_PKCa_PRKCG_ST	P28329	CHAT	P05129	PRKCG	S558	S556R	556	Missense	proximal	-2	no	134.661	144.073	EPSD	TCGA;COSMIC	98.543	Up-regulation
AGC_PKC_PKCa_PRKCG_ST	P28329	CHAT	P05129	PRKCG	S558	G565E	565	Missense	distal	7	no	134.661	141.545	EPSD	TCGA;COSMIC	98.543	Up-regulation
AGC_PKC_PKCa_PRKCG_ST	P08138	NGFR	P05129	PRKCG	S277	N276S	276	Missense	proximal	-1	no	131.284	134.937	PhosphoSitePlus	TCGA;COSMIC	98.543	Up-regulation
AGC_PKC_PKCa_PRKCG_ST	P08138	NGFR	P05129	PRKCG	T323	S325L	325	Missense	proximal	2	no	96.638	98.772	EPSD	TCGA;COSMIC	98.543	Gain
TK_PDGFR_FLT3_Y	P36888	FLT3	P36888	FLT3	Y589	S584C	584	Missense	distal	-5	no	1.059	1.034	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	0.779	Down-regulation
TK_PDGFR_FLT3_Y	P36888	FLT3	P36888	FLT3	Y589	G583S	583	Missense	distal	-6	no	1.059	0.870	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	0.779	Down-regulation
TK_PDGFR_FLT3_Y	P36888	FLT3	P36888	FLT3	Y589	V592I	592	Missense	distal	3	no	1.059	1.054	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	0.779	Down-regulation
TK_PDGFR_FLT3_Y	P36888	FLT3	P36888	FLT3	Y591	S584C	584	Missense	distal	-7	no	1.561	1.578	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	0.779	Up-regulation
TK_PDGFR_FLT3_Y	P36888	FLT3	P36888	FLT3	Y591	Y597N	597	Missense	distal	6	no	1.561	1.428	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	0.779	Down-regulation
TK_PDGFR_FLT3_Y	P36888	FLT3	P36888	FLT3	Y591	V592I	592	Missense	proximal	1	no	1.561	1.551	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	0.779	Down-regulation
TK_PDGFR_FLT3_Y	P36888	FLT3	P36888	FLT3	Y597	Y597N	597	Missense	central	0	yes	1.311	0.000	EPSD	TCGA;ICGC;COSMIC	0.779	Loss
TK_PDGFR_FLT3_Y	P36888	FLT3	P36888	FLT3	Y597	L601P	601	Missense	distal	4	no	1.311	1.054	EPSD	TCGA;ICGC;COSMIC	0.779	Down-regulation
TK_PDGFR_FLT3_Y	P36888	FLT3	P36888	FLT3	Y597	V592I	592	Missense	distal	-5	no	1.311	1.295	EPSD	TCGA;ICGC;COSMIC	0.779	Down-regulation
TK_PDGFR_FLT3_Y	P36888	FLT3	P36888	FLT3	Y599	Y597N	597	Missense	proximal	-2	no	1.199	1.169	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	0.779	Down-regulation
TK_PDGFR_FLT3_Y	P36888	FLT3	P36888	FLT3	Y599	L601P	601	Missense	proximal	2	no	1.199	1.163	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	0.779	Down-regulation
TK_PDGFR_FLT3_Y	P36888	FLT3	P36888	FLT3	Y599	V592I	592	Missense	distal	-7	no	1.199	1.215	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	0.779	Up-regulation
TK_PDGFR_FLT3_Y	P36888	FLT3	P36888	FLT3	Y726	S724R	724	Missense	proximal	-2	no	1.198	1.187	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	0.779	Down-regulation
TK_PDGFR_FLT3_Y	P36888	FLT3	P36888	FLT3	Y726	H721N	721	Missense	distal	-5	no	1.198	1.163	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	0.779	Down-regulation
TK_PDGFR_FLT3_Y	P36888	FLT3	P36888	FLT3	Y793	G798R	798	Missense	distal	5	no	0.779	0.783	EPSD	TCGA;ICGC;COSMIC	0.779	Up-regulation
TK_PDGFR_FLT3_Y	P36888	FLT3	P36888	FLT3	Y842	G846D	846	Missense	distal	4	no	1.234	1.202	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	0.779	Down-regulation
TK_PDGFR_FLT3_Y	P36888	FLT3	P36888	FLT3	Y842	R849H	849	Missense	distal	7	no	1.234	1.215	EPSD;PhosphoSitePlus	TCGA;COSMIC	0.779	Down-regulation
TK_PDGFR_FLT3_Y	P36888	FLT3	P36888	FLT3	Y842	D839H	839	Missense	distal	-3	no	1.234	1.221	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	0.779	Down-regulation
TK_PDGFR_FLT3_Y	P36888	FLT3	P36888	FLT3	Y842	V843A	843	Missense	proximal	1	no	1.234	1.221	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	0.779	Down-regulation
TK_PDGFR_FLT3_Y	P36888	FLT3	P36888	FLT3	Y842	M837L	837	Missense	distal	-5	no	1.234	1.154	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	0.779	Down-regulation
TK_PDGFR_FLT3_Y	P36888	FLT3	P36888	FLT3	Y955	A953T	953	Missense	proximal	-2	no	1.584	1.572	PhosphoSitePlus;EPSD	TCGA;COSMIC	0.779	Down-regulation
TK_PDGFR_FLT3_Y	P36888	FLT3	P36888	FLT3	Y955	R961P	961	Missense	distal	6	no	1.584	1.576	PhosphoSitePlus;EPSD	TCGA;COSMIC	0.779	Down-regulation
TK_PDGFR_FLT3_Y	P36888	FLT3	P36888	FLT3	Y955	A953V	953	Missense	proximal	-2	no	1.584	1.567	PhosphoSitePlus;EPSD	TCGA;COSMIC	0.779	Down-regulation
TK_PDGFR_FLT3_Y	P36888	FLT3	P36888	FLT3	Y969	P966H	966	Missense	distal	-3	no	1.490	1.449	EPSD;PhosphoSitePlus	TCGA	0.779	Down-regulation
TK_PDGFR_FLT3_Y	P36888	FLT3	P36888	FLT3	Y969	Q970K	970	Missense	proximal	1	no	1.490	1.486	EPSD;PhosphoSitePlus	TCGA;COSMIC	0.779	Down-regulation
TK_PDGFR_FLT3_Y	P36888	FLT3	P36888	FLT3	Y969	S963L	963	Missense	distal	-6	no	1.490	1.712	EPSD;PhosphoSitePlus	TCGA;COSMIC	0.779	Up-regulation
TK_PDGFR_FLT3_Y	P36888	FLT3	P36888	FLT3	Y969	E964A	964	Missense	distal	-5	no	1.490	1.480	EPSD;PhosphoSitePlus	TCGA;COSMIC	0.779	Down-regulation
TK_PDGFR_FLT3_Y	Q15118	PDK1	P36888	FLT3	Y243	E249K	249	Missense	distal	6	no	1.394	1.341	PhosphoSitePlus	TCGA;ICGC;COSMIC	0.779	Down-regulation
TK_PDGFR_FLT3_Y	Q15118	PDK1	P36888	FLT3	Y243	Y244C	244	Missense	proximal	1	no	1.394	1.385	PhosphoSitePlus	TCGA;ICGC	0.779	Down-regulation
TK_PDGFR_FLT3_Y	Q15118	PDK1	P36888	FLT3	Y243	R237W	237	Missense	distal	-6	no	1.394	1.379	PhosphoSitePlus	TCGA;ICGC;COSMIC	0.779	Down-regulation
TK_PDGFR_FLT3_Y	Q15118	PDK1	P36888	FLT3	Y243	S247C	247	Missense	distal	4	no	1.394	1.411	PhosphoSitePlus	TCGA;ICGC;COSMIC	0.779	Up-regulation
CMGC_SRPK_SRPK1_ST	Q96SB4	SRPK1	Q96SB4	SRPK1	S249	S249Y	249	Missense	central	0	yes	57.729	0.000	EPSD	TCGA;COSMIC	48.822	Loss
CMGC_SRPK_SRPK1_ST	Q96SB4	SRPK1	Q96SB4	SRPK1	S249	P244H	244	Missense	distal	-5	no	57.729	56.536	EPSD	TCGA	48.822	Down-regulation
CMGC_SRPK_SRPK1_ST	Q96SB4	SRPK1	Q96SB4	SRPK1	S309	E308Q	308	Missense	proximal	-1	no	75.655	74.839	PhosphoSitePlus;EPSD	TCGA;COSMIC	48.822	Down-regulation
CMGC_SRPK_SRPK1_ST	Q96SB4	SRPK1	Q96SB4	SRPK1	S309	E310D	310	Missense	proximal	1	no	75.655	72.198	PhosphoSitePlus;EPSD	TCGA;COSMIC	48.822	Down-regulation
CMGC_SRPK_SRPK1_ST	Q96SB4	SRPK1	Q96SB4	SRPK1	S311	E308Q	308	Missense	distal	-3	no	74.113	73.245	EPSD	TCGA;COSMIC	48.822	Down-regulation
CMGC_SRPK_SRPK1_ST	Q96SB4	SRPK1	Q96SB4	SRPK1	S311	K318N	318	Missense	distal	7	no	74.113	74.709	EPSD	TCGA;COSMIC	48.822	Up-regulation
CMGC_SRPK_SRPK1_ST	Q96SB4	SRPK1	Q96SB4	SRPK1	S311	E310D	310	Missense	proximal	-1	no	74.113	68.308	EPSD	TCGA;COSMIC	48.822	Down-regulation
CMGC_SRPK_SRPK1_ST	Q96SB4	SRPK1	Q96SB4	SRPK1	S587	A583S	583	Missense	distal	-4	no	54.494	65.473	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	48.822	Up-regulation
CMGC_SRPK_SRPK1_ST	Q07955	SRSF1	Q96SB4	SRPK1	S91	R97G	97	Missense	distal	6	no	55.432	49.499	EPSD	TCGA;ICGC;COSMIC	48.822	Down-regulation
CMGC_SRPK_SRPK1_ST	Q07955	SRSF1	Q96SB4	SRPK1	S116	V123L	123	Missense	distal	7	no	76.136	76.696	EPSD	TCGA;ICGC;COSMIC	48.822	Up-regulation
CMGC_SRPK_SRPK1_ST	Q07955	SRSF1	Q96SB4	SRPK1	S119	V123L	123	Missense	distal	4	no	68.718	70.325	EPSD	TCGA;ICGC;COSMIC	48.822	Up-regulation
CMGC_SRPK_SRPK1_ST	Q07955	SRSF1	Q96SB4	SRPK1	S131	S133C	133	Missense	proximal	2	no	50.381	35.580	EPSD	TCGA;ICGC;COSMIC	48.822	Loss
CMGC_SRPK_SRPK1_ST	Q07955	SRSF1	Q96SB4	SRPK1	S131	Q135H	135	Missense	distal	4	no	50.381	50.581	EPSD	TCGA;ICGC;COSMIC	48.822	Up-regulation
CMGC_SRPK_SRPK1_ST	Q07955	SRSF1	Q96SB4	SRPK1	S131	K138N	138	Missense	distal	7	no	50.381	50.977	EPSD	TCGA;ICGC;COSMIC;GDSC;CCLE	48.822	Up-regulation
CMGC_SRPK_SRPK1_ST	Q07955	SRSF1	Q96SB4	SRPK1	S182	R181G	181	Missense	proximal	-1	no	62.623	34.894	EPSD	TCGA;ICGC;COSMIC	48.822	Loss
CMGC_SRPK_SRPK1_ST	Q07955	SRSF1	Q96SB4	SRPK1	S182	D176G	176	Missense	distal	-6	no	62.623	63.446	EPSD	TCGA;ICGC;COSMIC	48.822	Up-regulation
CMGC_SRPK_SRPK1_ST	Q07955	SRSF1	Q96SB4	SRPK1	S182	Y189H	189	Missense	distal	7	no	62.623	61.721	EPSD	TCGA;ICGC;COSMIC	48.822	Down-regulation
CMGC_SRPK_SRPK1_ST	Q07955	SRSF1	Q96SB4	SRPK1	S199	D195H	195	Missense	distal	-4	no	117.477	116.867	EPSD	TCGA;ICGC;COSMIC	48.822	Down-regulation
CMGC_SRPK_SRPK1_ST	Q07955	SRSF1	Q96SB4	SRPK1	S199	R204K	204	Missense	distal	5	no	117.477	96.083	EPSD	TCGA;ICGC;COSMIC	48.822	Down-regulation
CMGC_SRPK_SRPK1_ST	Q07955	SRSF1	Q96SB4	SRPK1	S199	V194A	194	Missense	distal	-5	no	117.477	117.541	EPSD	TCGA;ICGC;COSMIC	48.822	Up-regulation
CMGC_SRPK_SRPK1_ST	Q07955	SRSF1	Q96SB4	SRPK1	S201	D195H	195	Missense	distal	-6	no	152.604	152.153	EPSD	TCGA;ICGC;COSMIC	48.822	Down-regulation
CMGC_SRPK_SRPK1_ST	Q07955	SRSF1	Q96SB4	SRPK1	S201	R204K	204	Missense	distal	3	no	152.604	131.696	EPSD	TCGA;ICGC;COSMIC	48.822	Down-regulation
CMGC_SRPK_SRPK1_ST	Q07955	SRSF1	Q96SB4	SRPK1	S201	V194A	194	Missense	distal	-7	no	152.604	152.741	EPSD	TCGA;ICGC;COSMIC	48.822	Up-regulation
CMGC_SRPK_SRPK1_ST	Q07955	SRSF1	Q96SB4	SRPK1	S205	R212S	212	Missense	distal	7	no	202.596	195.592	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	48.822	Down-regulation
CMGC_SRPK_SRPK1_ST	Q07955	SRSF1	Q96SB4	SRPK1	S205	R204K	204	Missense	proximal	-1	no	202.596	173.538	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	48.822	Down-regulation
CMGC_SRPK_SRPK1_ST	Q07955	SRSF1	Q96SB4	SRPK1	S207	R212S	212	Missense	distal	5	no	256.013	235.651	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	48.822	Down-regulation
CMGC_SRPK_SRPK1_ST	Q07955	SRSF1	Q96SB4	SRPK1	S207	R204K	204	Missense	distal	-3	no	256.013	216.692	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	48.822	Down-regulation
CMGC_SRPK_SRPK1_ST	Q07955	SRSF1	Q96SB4	SRPK1	S209	R212S	212	Missense	distal	3	no	256.434	236.921	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	48.822	Down-regulation
CMGC_SRPK_SRPK1_ST	Q07955	SRSF1	Q96SB4	SRPK1	S209	R204K	204	Missense	distal	-5	no	256.434	244.857	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	48.822	Down-regulation
CMGC_SRPK_SRPK1_ST	Q07955	SRSF1	Q96SB4	SRPK1	S211	R212S	212	Missense	proximal	1	no	268.077	252.147	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	48.822	Down-regulation
CMGC_SRPK_SRPK1_ST	Q07955	SRSF1	Q96SB4	SRPK1	S211	R204K	204	Missense	distal	-7	no	268.077	251.357	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	48.822	Down-regulation
CMGC_SRPK_SRPK1_ST	Q07955	SRSF1	Q96SB4	SRPK1	S213	R212S	212	Missense	proximal	-1	no	290.386	262.507	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	48.822	Down-regulation
CMGC_SRPK_SRPK1_ST	Q07955	SRSF1	Q96SB4	SRPK1	S215	R212S	212	Missense	distal	-3	no	285.073	246.854	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	48.822	Down-regulation
CMGC_SRPK_SRPK1_ST	Q07955	SRSF1	Q96SB4	SRPK1	S217	R212S	212	Missense	distal	-5	no	285.952	274.524	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	48.822	Down-regulation
CMGC_SRPK_SRPK1_ST	Q07955	SRSF1	Q96SB4	SRPK1	S219	R212S	212	Missense	distal	-7	no	282.286	267.311	PhosphoSitePlus;EPSD	TCGA;ICGC;COSMIC	48.822	Down-regulation
CMGC_SRPK_SRPK1_ST	Q07955	SRSF1	Q96SB4	SRPK1	S231	S238F	238	Missense	distal	7	no	185.483	183.724	EPSD	TCGA;ICGC;COSMIC	48.822	Down-regulation
CMGC_SRPK_SRPK1_ST	Q07955	SRSF1	Q96SB4	SRPK1	S231	P235L	235	Missense	distal	4	no	185.483	182.905	EPSD	TCGA;ICGC;COSMIC	48.822	Down-regulation
CMGC_SRPK_SRPK1_ST	Q07955	SRSF1	Q96SB4	SRPK1	S234	S238F	238	Missense	distal	4	no	75.861	67.345	EPSD	TCGA;ICGC;COSMIC	48.822	Down-regulation
CMGC_SRPK_SRPK1_ST	Q07955	SRSF1	Q96SB4	SRPK1	S234	R240S	240	Missense	distal	6	no	75.861	79.362	EPSD	TCGA;ICGC;COSMIC	48.822	Up-regulation
CMGC_SRPK_SRPK1_ST	Q07955	SRSF1	Q96SB4	SRPK1	S234	P235L	235	Missense	proximal	1	no	75.861	71.848	EPSD	TCGA;ICGC;COSMIC	48.822	Down-regulation
CMGC_SRPK_SRPK1_ST	Q07955	SRSF1	Q96SB4	SRPK1	S238	S238F	238	Missense	central	0	yes	127.457	0.000	EPSD	TCGA;ICGC;COSMIC	48.822	Loss
CMGC_SRPK_SRPK1_ST	Q07955	SRSF1	Q96SB4	SRPK1	S238	R240S	240	Missense	proximal	2	no	127.457	138.485	EPSD	TCGA;ICGC;COSMIC	48.822	Up-regulation
CMGC_SRPK_SRPK1_ST	Q07955	SRSF1	Q96SB4	SRPK1	S238	P235L	235	Missense	distal	-3	no	127.457	119.069	EPSD	TCGA;ICGC;COSMIC	48.822	Down-regulation
CMGC_SRPK_SRPK1_ST	Q07955	SRSF1	Q96SB4	SRPK1	S238	S244Y	244	Missense	distal	6	no	127.457	116.295	EPSD	TCGA;ICGC;COSMIC	48.822	Down-regulation
CMGC_SRPK_SRPK1_ST	Q07955	SRSF1	Q96SB4	SRPK1	S242	S238F	238	Missense	distal	-4	no	125.873	116.288	EPSD	TCGA;ICGC;COSMIC	48.822	Down-regulation
CMGC_SRPK_SRPK1_ST	Q07955	SRSF1	Q96SB4	SRPK1	S242	R240S	240	Missense	proximal	-2	no	125.873	134.415	EPSD	TCGA;ICGC;COSMIC	48.822	Up-regulation
CMGC_SRPK_SRPK1_ST	Q07955	SRSF1	Q96SB4	SRPK1	S242	P235L	235	Missense	distal	-7	no	125.873	121.688	EPSD	TCGA;ICGC;COSMIC	48.822	Down-regulation
CMGC_SRPK_SRPK1_ST	Q07955	SRSF1	Q96SB4	SRPK1	S242	S244Y	244	Missense	proximal	2	no	125.873	109.820	EPSD	TCGA;ICGC;COSMIC	48.822	Down-regulation
CMGC_SRPK_SRPK1_ST	Q07955	SRSF1	Q96SB4	SRPK1	S244	S238F	238	Missense	distal	-6	no	126.258	119.061	EPSD	TCGA;ICGC;COSMIC	48.822	Down-regulation
CMGC_SRPK_SRPK1_ST	Q07955	SRSF1	Q96SB4	SRPK1	S244	R240S	240	Missense	distal	-4	no	126.258	133.180	EPSD	TCGA;ICGC;COSMIC	48.822	Up-regulation
CMGC_SRPK_SRPK1_ST	Q07955	SRSF1	Q96SB4	SRPK1	S244	S244Y	244	Missense	central	0	yes	126.258	0.000	EPSD	TCGA;ICGC;COSMIC	48.822	Loss
CMGC_SRPK_SRPK1_ST	Q07955	SRSF1	Q96SB4	SRPK1	S246	R240S	240	Missense	distal	-6	no	135.367	140.128	EPSD	TCGA;ICGC;COSMIC	48.822	Up-regulation
CMGC_SRPK_SRPK1_ST	Q07955	SRSF1	Q96SB4	SRPK1	S246	S244Y	244	Missense	proximal	-2	no	135.367	121.241	EPSD	TCGA;ICGC;COSMIC	48.822	Down-regulation
CMGC_SRPK_SRPK1_ST	Q07955	SRSF1	Q96SB4	SRPK1	T248	S244Y	244	Missense	distal	-4	no	116.514	105.963	EPSD	TCGA;ICGC;COSMIC	48.822	Down-regulation
CMGC_SRPK_SRPK1_ST	Q9Y5S9	RBM8A	Q96SB4	SRPK1	S42	E44Q	44	Missense	proximal	2	no	79.281	74.895	EPSD	TCGA;COSMIC	48.822	Down-regulation
CMGC_SRPK_SRPK1_ST	Q9Y5S9	RBM8A	Q96SB4	SRPK1	S42	R38S	38	Missense	distal	-4	no	79.281	86.203	EPSD	TCGA;ICGC;COSMIC	48.822	Up-regulation
CMGC_SRPK_SRPK1_ST	Q9Y5S9	RBM8A	Q96SB4	SRPK1	S46	E44Q	44	Missense	proximal	-2	no	96.357	92.707	EPSD	TCGA;COSMIC	48.822	Down-regulation
CMGC_SRPK_SRPK1_ST	Q9Y5S9	RBM8A	Q96SB4	SRPK1	S46	E52G	52	Missense	distal	6	no	96.357	95.228	EPSD	TCGA;ICGC;COSMIC	48.822	Down-regulation
CMGC_SRPK_SRPK1_ST	Q9Y5S9	RBM8A	Q96SB4	SRPK1	S56	D60H	60	Missense	distal	4	no	61.208	60.956	EPSD	TCGA;ICGC;COSMIC	48.822	Down-regulation
CMGC_SRPK_SRPK1_ST	Q9Y5S9	RBM8A	Q96SB4	SRPK1	S56	E52G	52	Missense	distal	-4	no	61.208	60.383	EPSD	TCGA;ICGC;COSMIC	48.822	Down-regulation
CMGC_SRPK_SRPK1_ST	Q9Y5S9	RBM8A	Q96SB4	SRPK1	S166	R172T	172	Missense	distal	6	no	184.253	174.805	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	48.822	Down-regulation
CMGC_SRPK_SRPK1_ST	Q9Y5S9	RBM8A	Q96SB4	SRPK1	S166	R163Q	163	Missense	distal	-3	no	184.253	146.789	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	48.822	Down-regulation
CMGC_SRPK_SRPK1_ST	Q9Y5S9	RBM8A	Q96SB4	SRPK1	S166	R164I	164	Missense	proximal	-2	no	184.253	178.924	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	48.822	Down-regulation
CMGC_SRPK_SRPK1_ST	Q9Y5S9	RBM8A	Q96SB4	SRPK1	S166	R173L	173	Missense	distal	7	no	184.253	174.808	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	48.822	Down-regulation
CMGC_SRPK_SRPK1_ST	Q9Y5S9	RBM8A	Q96SB4	SRPK1	S166	R173H	173	Missense	distal	7	no	184.253	175.700	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	48.822	Down-regulation
CMGC_SRPK_SRPK1_ST	Q9Y5S9	RBM8A	Q96SB4	SRPK1	S166	R160I	160	Missense	distal	-6	no	184.253	181.436	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	48.822	Down-regulation
CMGC_SRPK_SRPK1_ST	Q9Y5S9	RBM8A	Q96SB4	SRPK1	S168	R172T	172	Missense	distal	4	no	189.678	183.747	PhosphoSitePlus;EPSD	TCGA;ICGC;COSMIC	48.822	Down-regulation
CMGC_SRPK_SRPK1_ST	Q9Y5S9	RBM8A	Q96SB4	SRPK1	S168	R163Q	163	Missense	distal	-5	no	189.678	178.511	PhosphoSitePlus;EPSD	TCGA;ICGC;COSMIC	48.822	Down-regulation
CMGC_SRPK_SRPK1_ST	Q9Y5S9	RBM8A	Q96SB4	SRPK1	S168	R164I	164	Missense	distal	-4	no	189.678	186.522	PhosphoSitePlus;EPSD	TCGA;ICGC;COSMIC	48.822	Down-regulation
CMGC_SRPK_SRPK1_ST	Q9Y5S9	RBM8A	Q96SB4	SRPK1	S168	R173L	173	Missense	distal	5	no	189.678	166.610	PhosphoSitePlus;EPSD	TCGA;ICGC;COSMIC	48.822	Down-regulation
CMGC_SRPK_SRPK1_ST	Q9Y5S9	RBM8A	Q96SB4	SRPK1	S168	R173H	173	Missense	distal	5	no	189.678	168.918	PhosphoSitePlus;EPSD	TCGA;ICGC;COSMIC	48.822	Down-regulation
AGC_PKC_PKCi_PRKCZ_ST	P60484	PTEN	Q05513	PRKCZ	S113	W111R	111	Missense	proximal	-2	no	19.299	37.473	EPSD	TCGA;ICGC;COSMIC;GDSC;CCLE	31.494	Gain
AGC_PKC_PKCi_PRKCZ_ST	P60484	PTEN	Q05513	PRKCZ	S370	E373K	373	Missense	distal	3	no	22.192	31.635	EPSD	TCGA;ICGC	31.494	Gain
AGC_PKC_PKCi_PRKCZ_ST	P60484	PTEN	Q05513	PRKCZ	S380	E373K	373	Missense	distal	-7	no	40.810	46.630	PhosphoSitePlus;EPSD	TCGA;ICGC	31.494	Up-regulation
AGC_PKC_PKCi_PRKCZ_ST	Q9Y6Q9	NCOA3	Q05513	PRKCZ	S13	L8V	8	Missense	distal	-5	no	33.562	33.300	EPSD	TCGA;ICGC;COSMIC	31.494	Down-regulation
AGC_PKC_PKCi_PRKCZ_ST	Q9Y6Q9	NCOA3	Q05513	PRKCZ	S13	L11M	11	Missense	proximal	-2	no	33.562	35.714	EPSD	TCGA;ICGC;COSMIC	31.494	Up-regulation
AGC_PKC_PKCi_PRKCZ_ST	Q9Y6Q9	NCOA3	Q05513	PRKCZ	S101	T103A	103	Missense	proximal	2	no	44.264	45.876	EPSD	TCGA;ICGC;COSMIC	31.494	Up-regulation
AGC_PKC_PKCi_PRKCZ_ST	Q9Y6Q9	NCOA3	Q05513	PRKCZ	S101	G106R	106	Missense	distal	5	no	44.264	44.703	EPSD	TCGA;ICGC;COSMIC	31.494	Up-regulation
AGC_PKC_PKCi_PRKCZ_ST	Q9Y6Q9	NCOA3	Q05513	PRKCZ	S101	D99N	99	Missense	proximal	-2	no	44.264	38.186	EPSD	TCGA;ICGC;COSMIC	31.494	Down-regulation
AGC_PKC_PKCi_PRKCZ_ST	Q9Y6Q9	NCOA3	Q05513	PRKCZ	S101	D94N	94	Missense	distal	-7	no	44.264	41.453	EPSD	TCGA;ICGC;COSMIC	31.494	Down-regulation
AGC_PKC_PKCi_PRKCZ_ST	Q9Y6Q9	NCOA3	Q05513	PRKCZ	S306	G310W	310	Missense	distal	4	no	39.116	30.674	EPSD	TCGA;ICGC;COSMIC	31.494	Loss
AGC_PKC_PKCi_PRKCZ_ST	Q9Y6Q9	NCOA3	Q05513	PRKCZ	S413	P412A	412	Missense	proximal	-1	no	30.230	31.779	EPSD	TCGA;ICGC;COSMIC	31.494	Gain
AGC_PKC_PKCi_PRKCZ_ST	Q9Y6Q9	NCOA3	Q05513	PRKCZ	T1059	L1060F	1060	Missense	proximal	1	no	33.442	34.385	PhosphoSitePlus;EPSD	TCGA;COSMIC	31.494	Up-regulation
AGC_PKC_PKCi_PRKCZ_ST	Q9Y6Q9	NCOA3	Q05513	PRKCZ	S1062	L1060F	1060	Missense	proximal	-2	no	41.445	38.697	EPSD;PhosphoSitePlus	TCGA;COSMIC	31.494	Down-regulation
AGC_PKC_PKCi_PRKCZ_ST	Q9Y6Q9	NCOA3	Q05513	PRKCZ	T1067	L1060F	1060	Missense	distal	-7	no	34.523	32.985	EPSD;PhosphoSitePlus	TCGA;COSMIC	31.494	Down-regulation
AGC_PKC_PKCi_PRKCZ_ST	Q9Y6Q9	NCOA3	Q05513	PRKCZ	T1067	R1074K	1074	Missense	distal	7	no	34.523	35.148	EPSD;PhosphoSitePlus	TCGA;COSMIC	31.494	Up-regulation
AGC_PKC_PKCi_PRKCZ_ST	Q16625	OCLN	Q05513	PRKCZ	S45	P48T	48	Missense	distal	3	no	27.128	33.993	EPSD	TCGA;ICGC	31.494	Gain
AGC_PKC_PKCi_PRKCZ_ST	Q16625	OCLN	Q05513	PRKCZ	S163	R170I	170	Missense	distal	7	no	29.199	31.951	EPSD	TCGA;ICGC	31.494	Gain
AGC_PKC_PKCi_PRKCZ_ST	Q16625	OCLN	Q05513	PRKCZ	S302	D307N	307	Missense	distal	5	no	34.086	34.170	EPSD	TCGA;ICGC;COSMIC	31.494	Up-regulation
AGC_PKC_PKCi_PRKCZ_ST	Q16625	OCLN	Q05513	PRKCZ	S321	S327F	327	Missense	distal	6	no	42.426	38.224	EPSD	TCGA;COSMIC	31.494	Down-regulation
AGC_PKC_PKCi_PRKCZ_ST	Q16625	OCLN	Q05513	PRKCZ	S321	V316A	316	Missense	distal	-5	no	42.426	39.838	EPSD	TCGA	31.494	Down-regulation
AGC_PKC_PKCi_PRKCZ_ST	Q16625	OCLN	Q05513	PRKCZ	S369	G371D	371	Missense	proximal	2	no	32.247	37.456	EPSD	TCGA;ICGC	31.494	Up-regulation
AGC_PKC_PKCi_PRKCZ_ST	Q16625	OCLN	Q05513	PRKCZ	T403	G405D	405	Missense	proximal	2	no	36.867	42.076	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	31.494	Up-regulation
AGC_PKC_PKCi_PRKCZ_ST	Q16625	OCLN	Q05513	PRKCZ	T403	E407K	407	Missense	distal	4	no	36.867	38.534	EPSD;PhosphoSitePlus	TCGA;ICGC;GDSC;CCLE	31.494	Up-regulation
AGC_PKC_PKCi_PRKCZ_ST	Q16625	OCLN	Q05513	PRKCZ	T404	E407K	407	Missense	distal	3	no	26.456	35.899	PhosphoSitePlus;EPSD	TCGA;ICGC;GDSC;CCLE	31.494	Gain
AGC_PKC_PKCi_PRKCZ_ST	Q16625	OCLN	Q05513	PRKCZ	S490	S495R	495	Missense	distal	5	no	31.984	32.570	EPSD	TCGA;ICGC	31.494	Up-regulation
AGC_PKC_PKCi_PRKCZ_ST	Q7KZI7	MARK2	Q05513	PRKCZ	S29	R36W	36	Missense	distal	7	no	31.368	34.498	EPSD	TCGA;ICGC;COSMIC	31.494	Gain
AGC_PKC_PKCi_PRKCZ_ST	Q7KZI7	MARK2	Q05513	PRKCZ	S30	R36W	36	Missense	distal	6	no	33.883	26.148	EPSD	TCGA;ICGC;COSMIC	31.494	Loss
AGC_PKC_PKCi_PRKCZ_ST	Q7KZI7	MARK2	Q05513	PRKCZ	S30	G37S	37	Missense	distal	7	no	33.883	31.526	EPSD	TCGA	31.494	Down-regulation
AGC_PKC_PKCi_PRKCZ_ST	Q7KZI7	MARK2	Q05513	PRKCZ	S30	M34V	34	Missense	distal	4	no	33.883	27.331	EPSD	TCGA;ICGC;COSMIC	31.494	Loss
AGC_PKC_PKCi_PRKCZ_ST	Q7KZI7	MARK2	Q05513	PRKCZ	S43	R36W	36	Missense	distal	-7	no	35.026	26.875	EPSD	TCGA;ICGC;COSMIC	31.494	Loss
AGC_PKC_PKCi_PRKCZ_ST	Q7KZI7	MARK2	Q05513	PRKCZ	S43	G37S	37	Missense	distal	-6	no	35.026	35.042	EPSD	TCGA	31.494	Up-regulation
AGC_PKC_PKCi_PRKCZ_ST	Q7KZI7	MARK2	Q05513	PRKCZ	T208	K205Q	205	Missense	distal	-3	no	41.261	34.512	EPSD	TCGA;COSMIC	31.494	Down-regulation
AGC_PKC_PKCi_PRKCZ_ST	Q7KZI7	MARK2	Q05513	PRKCZ	T208	K205N	205	Missense	distal	-3	no	41.261	33.504	EPSD	TCGA;COSMIC	31.494	Down-regulation
AGC_PKC_PKCi_PRKCZ_ST	Q7KZI7	MARK2	Q05513	PRKCZ	T208	P213L	213	Missense	distal	5	no	41.261	41.173	EPSD	TCGA;ICGC;COSMIC	31.494	Down-regulation
AGC_PKC_PKCi_PRKCZ_ST	Q7KZI7	MARK2	Q05513	PRKCZ	S290	E296Q	296	Missense	distal	6	no	38.492	37.372	EPSD	TCGA;COSMIC	31.494	Down-regulation
AGC_PKC_PKCi_PRKCZ_ST	Q7KZI7	MARK2	Q05513	PRKCZ	S290	E296V	296	Missense	distal	6	no	38.492	38.495	EPSD	TCGA;COSMIC	31.494	Up-regulation
AGC_PKC_PKCi_PRKCZ_ST	Q7KZI7	MARK2	Q05513	PRKCZ	T294	E296Q	296	Missense	proximal	2	no	44.382	48.661	EPSD	TCGA;COSMIC	31.494	Up-regulation
AGC_PKC_PKCi_PRKCZ_ST	Q7KZI7	MARK2	Q05513	PRKCZ	T294	E296V	296	Missense	proximal	2	no	44.382	48.844	EPSD	TCGA;COSMIC	31.494	Up-regulation
AGC_PKC_PKCi_PRKCZ_ST	Q7KZI7	MARK2	Q05513	PRKCZ	S398	V399M	399	Missense	proximal	1	no	31.429	31.831	EPSD	TCGA;ICGC;COSMIC	31.494	Gain
AGC_PKC_PKCi_PRKCZ_ST	Q7KZI7	MARK2	Q05513	PRKCZ	S409	N402S	402	Missense	distal	-7	no	36.127	36.327	EPSD	TCGA;ICGC;COSMIC	31.494	Up-regulation
AGC_PKC_PKCi_PRKCZ_ST	Q7KZI7	MARK2	Q05513	PRKCZ	S443	E438Q	438	Missense	distal	-5	no	53.685	53.487	EPSD	TCGA;COSMIC	31.494	Down-regulation
AGC_PKC_PKCi_PRKCZ_ST	Q7KZI7	MARK2	Q05513	PRKCZ	S443	R436Q	436	Missense	distal	-7	no	53.685	49.972	EPSD	TCGA;COSMIC	31.494	Down-regulation
AGC_PKC_PKCi_PRKCZ_ST	Q7KZI7	MARK2	Q05513	PRKCZ	S443	D440G	440	Missense	distal	-3	no	53.685	47.921	EPSD	TCGA;COSMIC	31.494	Down-regulation
AGC_PKC_PKCi_PRKCZ_ST	Q7KZI7	MARK2	Q05513	PRKCZ	T480	P487S	487	Missense	distal	7	no	33.446	30.137	EPSD	TCGA;COSMIC	31.494	Loss
AGC_PKC_PKCi_PRKCZ_ST	Q7KZI7	MARK2	Q05513	PRKCZ	S533	R528C	528	Missense	distal	-5	no	40.927	44.512	EPSD	TCGA;COSMIC	31.494	Up-regulation
AGC_PKC_PKCi_PRKCZ_ST	Q7KZI7	MARK2	Q05513	PRKCZ	S592	H598N	598	Missense	distal	6	no	40.240	37.501	EPSD	TCGA	31.494	Down-regulation
AGC_PKC_PKCi_PRKCZ_ST	Q7KZI7	MARK2	Q05513	PRKCZ	S592	T596P	596	Missense	distal	4	no	40.240	38.464	EPSD	TCGA;COSMIC	31.494	Down-regulation
AGC_PKC_PKCi_PRKCZ_ST	Q7KZI7	MARK2	Q05513	PRKCZ	S592	R594Q	594	Missense	proximal	2	no	40.240	32.371	EPSD	TCGA;COSMIC	31.494	Down-regulation
AGC_PKC_PKCi_PRKCZ_ST	Q7KZI7	MARK2	Q05513	PRKCZ	T596	H598N	598	Missense	proximal	2	no	45.293	39.546	PhosphoSitePlus	TCGA	31.494	Down-regulation
AGC_PKC_PKCi_PRKCZ_ST	Q7KZI7	MARK2	Q05513	PRKCZ	T596	T596P	596	Missense	central	0	yes	45.293	0.000	PhosphoSitePlus	TCGA;COSMIC	31.494	Loss
AGC_PKC_PKCi_PRKCZ_ST	Q7KZI7	MARK2	Q05513	PRKCZ	T596	R594Q	594	Missense	proximal	-2	no	45.293	35.307	PhosphoSitePlus	TCGA;COSMIC	31.494	Down-regulation
AGC_PKC_PKCi_PRKCZ_ST	Q7KZI7	MARK2	Q05513	PRKCZ	S648	R644H	644	Missense	distal	-4	no	44.027	44.243	EPSD	TCGA;COSMIC	31.494	Up-regulation
AGC_PKC_PKCi_PRKCZ_ST	Q7KZI7	MARK2	Q05513	PRKCZ	S722	R715H	715	Missense	distal	-7	no	33.335	29.984	EPSD	TCGA;COSMIC	31.494	Loss
AGC_PKC_PKCi_PRKCZ_ST	Q7KZI7	MARK2	Q05513	PRKCZ	S722	E729Q	729	Missense	distal	7	no	33.335	31.134	EPSD	TCGA;COSMIC	31.494	Loss
AGC_PKC_PKCi_PRKCZ_ST	Q7KZI7	MARK2	Q05513	PRKCZ	S722	N721S	721	Missense	proximal	-1	no	33.335	33.592	EPSD	TCGA;COSMIC	31.494	Up-regulation
AGC_PKC_PKCi_PRKCZ_ST	Q7KZI7	MARK2	Q05513	PRKCZ	S722	R715C	715	Missense	distal	-7	no	33.335	27.501	EPSD	TCGA;COSMIC	31.494	Loss
AGC_PKC_PKCi_PRKCZ_ST	Q7KZI7	MARK2	Q05513	PRKCZ	S769	S769L	769	Missense	central	0	yes	45.513	0.000	EPSD	TCGA;COSMIC	31.494	Loss
AGC_PKC_PKCi_PRKCZ_ST	Q7KZI7	MARK2	Q05513	PRKCZ	S769	R767W	767	Missense	proximal	-2	no	45.513	27.340	EPSD	TCGA	31.494	Loss
AGC_PKC_PKCi_PRKCZ_ST	P10636	MAPT	Q05513	PRKCZ	T52	G55R	55	Missense	distal	3	no	30.196	33.719	EPSD	TCGA;ICGC;COSMIC	31.494	Gain
AGC_PKC_PKCi_PRKCZ_ST	P10636	MAPT	Q05513	PRKCZ	S171	R168H	168	Missense	distal	-3	no	39.858	31.430	EPSD	TCGA;ICGC;COSMIC	31.494	Loss
AGC_PKC_PKCi_PRKCZ_ST	P10636	MAPT	Q05513	PRKCZ	S171	R168C	168	Missense	distal	-3	no	39.858	19.825	EPSD	TCGA;ICGC;COSMIC	31.494	Loss
AGC_PKC_PKCi_PRKCZ_ST	P10636	MAPT	Q05513	PRKCZ	S341	E348V	348	Missense	distal	7	no	32.156	31.353	EPSD	TCGA;ICGC;COSMIC	31.494	Loss
AGC_PKC_PKCi_PRKCZ_ST	P10636	MAPT	Q05513	PRKCZ	S341	G339R	339	Missense	proximal	-2	no	32.156	42.850	EPSD	TCGA;ICGC;COSMIC	31.494	Up-regulation
AGC_PKC_PKCi_PRKCZ_ST	P10636	MAPT	Q05513	PRKCZ	S341	S341F	341	Missense	central	0	yes	32.156	0.000	EPSD	TCGA;ICGC;COSMIC	31.494	Loss
AGC_PKC_PKCi_PRKCZ_ST	P10636	MAPT	Q05513	PRKCZ	T386	G387R	387	Missense	proximal	1	no	30.025	31.739	EPSD	TCGA;COSMIC	31.494	Gain
AGC_PKC_PKCi_PRKCZ_ST	P10636	MAPT	Q05513	PRKCZ	S388	G387R	387	Missense	proximal	-1	no	31.313	31.767	EPSD	TCGA;COSMIC	31.494	Gain
AGC_PKC_PKCi_PRKCZ_ST	P10636	MAPT	Q05513	PRKCZ	S447	K440E	440	Missense	distal	-7	no	43.476	37.655	EPSD	TCGA;ICGC;COSMIC	31.494	Down-regulation
AGC_PKC_PKCi_PRKCZ_ST	P10636	MAPT	Q05513	PRKCZ	S447	S452C	452	Missense	distal	5	no	43.476	43.355	EPSD	TCGA;ICGC;COSMIC	31.494	Down-regulation
AGC_PKC_PKCi_PRKCZ_ST	P10636	MAPT	Q05513	PRKCZ	S447	S443F	443	Missense	distal	-4	no	43.476	43.588	EPSD	TCGA;ICGC;COSMIC	31.494	Up-regulation
AGC_PKC_PKCi_PRKCZ_ST	P10636	MAPT	Q05513	PRKCZ	S447	S444F	444	Missense	distal	-3	no	43.476	41.880	EPSD	TCGA;ICGC	31.494	Down-regulation
AGC_PKC_PKCi_PRKCZ_ST	P10636	MAPT	Q05513	PRKCZ	S447	S452Y	452	Missense	distal	5	no	43.476	43.614	EPSD	TCGA;ICGC;COSMIC	31.494	Up-regulation
AGC_PKC_PKCi_PRKCZ_ST	P61587	RND3	Q05513	PRKCZ	S7	R4I	4	Missense	distal	-3	no	56.159	37.013	EPSD	TCGA;ICGC	31.494	Down-regulation
AGC_PKC_PKCi_PRKCZ_ST	P61587	RND3	Q05513	PRKCZ	S11	I15S	15	Missense	distal	4	no	40.007	47.127	EPSD	TCGA;ICGC;COSMIC	31.494	Up-regulation
AGC_PKC_PKCi_PRKCZ_ST	P61587	RND3	Q05513	PRKCZ	S11	R4I	4	Missense	distal	-7	no	40.007	32.551	EPSD	TCGA;ICGC	31.494	Down-regulation
AGC_PKC_PKCi_PRKCZ_ST	P61587	RND3	Q05513	PRKCZ	S12	I15S	15	Missense	distal	3	no	39.179	43.096	EPSD	TCGA;ICGC;COSMIC	31.494	Up-regulation
AGC_PKC_PKCi_PRKCZ_ST	P61587	RND3	Q05513	PRKCZ	S210	R216W	216	Missense	distal	6	no	58.835	51.100	PhosphoSitePlus	TCGA;COSMIC;CCLE	31.494	Down-regulation
AGC_PKC_PKCi_PRKCZ_ST	P61587	RND3	Q05513	PRKCZ	S210	S210L	210	Missense	central	0	yes	58.835	0.000	PhosphoSitePlus	TCGA;COSMIC	31.494	Loss
AGC_PKC_PKCi_PRKCZ_ST	P61587	RND3	Q05513	PRKCZ	S210	V205G	205	Missense	distal	-5	no	58.835	57.660	PhosphoSitePlus	TCGA;COSMIC	31.494	Down-regulation
AGC_PKC_PKCi_PRKCZ_ST	P61587	RND3	Q05513	PRKCZ	S240	L233V	233	Missense	distal	-7	no	36.968	35.559	EPSD	TCGA;COSMIC	31.494	Down-regulation
AGC_PKC_PKCi_PRKCZ_ST	O43175	PHGDH	Q05513	PRKCZ	T57	R54P	54	Missense	distal	-3	no	36.729	17.858	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	31.494	Loss
AGC_PKC_PKCi_PRKCZ_ST	O43175	PHGDH	Q05513	PRKCZ	T57	D62N	62	Missense	distal	5	no	36.729	36.812	EPSD;PhosphoSitePlus	TCGA;COSMIC	31.494	Up-regulation
AGC_PKC_PKCi_PRKCZ_ST	O43175	PHGDH	Q05513	PRKCZ	T57	T57I	57	Missense	central	0	yes	36.729	0.000	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	31.494	Loss
AGC_PKC_PKCi_PRKCZ_ST	O43175	PHGDH	Q05513	PRKCZ	T78	L85M	85	Missense	distal	7	no	41.967	40.968	EPSD;PhosphoSitePlus	TCGA;ICGC	31.494	Down-regulation
AGC_PKC_PKCi_PRKCZ_ST	O43175	PHGDH	Q05513	PRKCZ	T78	N82S	82	Missense	distal	4	no	41.967	41.752	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	31.494	Down-regulation
AGC_PKC_PKCi_PRKCZ_ST	O43175	PHGDH	Q05513	PRKCZ	T78	R75S	75	Missense	distal	-3	no	41.967	28.541	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	31.494	Loss
AGC_PKC_PKCi_PRKCZ_ST	O43175	PHGDH	Q05513	PRKCZ	S166	R163Q	163	Missense	distal	-3	no	34.088	22.201	EPSD	TCGA;COSMIC	31.494	Loss
AGC_PKC_PKCi_PRKCZ_ST	O43175	PHGDH	Q05513	PRKCZ	S166	G173W	173	Missense	distal	7	no	34.088	34.904	EPSD	TCGA;ICGC	31.494	Up-regulation
AGC_PKC_PKCi_PRKCZ_ST	O43175	PHGDH	Q05513	PRKCZ	T288	A291T	291	Missense	distal	3	no	32.755	26.546	EPSD	TCGA;ICGC;COSMIC	31.494	Loss
AGC_PKC_PKCi_PRKCZ_ST	O43175	PHGDH	Q05513	PRKCZ	T288	P282L	282	Missense	distal	-6	no	32.755	32.503	EPSD	TCGA;ICGC;COSMIC	31.494	Down-regulation
AGC_PKC_PKCi_PRKCZ_ST	O43175	PHGDH	Q05513	PRKCZ	T288	C295Y	295	Missense	distal	7	no	32.755	31.812	EPSD	TCGA;ICGC;COSMIC	31.494	Down-regulation
AGC_PKC_PKCi_PRKCZ_ST	O43175	PHGDH	Q05513	PRKCZ	T288	A286V	286	Missense	proximal	-2	no	32.755	30.002	EPSD	TCGA;ICGC;COSMIC	31.494	Loss
AGC_PKC_PKCi_PRKCZ_ST	P53004	BLVRA	Q05513	PRKCZ	S21	G20S	20	Missense	proximal	-1	no	38.923	38.276	EPSD	TCGA	31.494	Down-regulation
AGC_PKC_PKCi_PRKCZ_ST	P53004	BLVRA	Q05513	PRKCZ	S21	R23W	23	Missense	proximal	2	no	38.923	24.586	EPSD	TCGA;ICGC;COSMIC	31.494	Loss
AGC_PKC_PKCi_PRKCZ_ST	Q13118	KLF10	Q05513	PRKCZ	S184	S184Y	184	Missense	central	0	yes	36.025	0.000	EPSD	TCGA;COSMIC	31.494	Loss
AGC_PKC_PKCi_PRKCZ_ST	Q13118	KLF10	Q05513	PRKCZ	S249	V248M	248	Missense	proximal	-1	no	31.583	32.134	EPSD	TCGA;COSMIC	31.494	Up-regulation
AGC_PKC_PKCi_PRKCZ_ST	Q13118	KLF10	Q05513	PRKCZ	S384	Y380C	380	Missense	distal	-4	no	39.136	39.469	PhosphoSitePlus;EPSD	TCGA;COSMIC	31.494	Up-regulation
AGC_PKC_PKCi_PRKCZ_ST	Q13118	KLF10	Q05513	PRKCZ	T394	T392M	392	Missense	proximal	-2	no	34.257	36.079	EPSD	TCGA;COSMIC	31.494	Up-regulation
AGC_PKC_PKCi_PRKCZ_ST	Q13118	KLF10	Q05513	PRKCZ	T422	R418K	418	Missense	distal	-4	no	33.343	33.445	EPSD	TCGA;COSMIC	31.494	Up-regulation
AGC_PKC_PKCi_PRKCZ_ST	Q13118	KLF10	Q05513	PRKCZ	T422	L416V	416	Missense	distal	-6	no	33.343	33.435	EPSD	TCGA	31.494	Up-regulation
AGC_PKC_PKCi_PRKCZ_ST	Q13118	KLF10	Q05513	PRKCZ	T422	T424M	424	Missense	proximal	2	no	33.343	35.510	EPSD	TCGA;COSMIC	31.494	Up-regulation
AGC_PKC_PKCi_PRKCZ_ST	Q13118	KLF10	Q05513	PRKCZ	T424	R418K	418	Missense	distal	-6	no	38.059	38.280	EPSD	TCGA;COSMIC	31.494	Up-regulation
AGC_PKC_PKCi_PRKCZ_ST	Q13118	KLF10	Q05513	PRKCZ	T424	A430V	430	Missense	distal	6	no	38.059	36.138	EPSD	TCGA;COSMIC	31.494	Down-regulation
AGC_PKC_PKCi_PRKCZ_ST	Q13118	KLF10	Q05513	PRKCZ	T424	T424M	424	Missense	central	0	yes	38.059	0.000	EPSD	TCGA;COSMIC	31.494	Loss
AGC_PKC_PKCi_PRKCZ_ST	P49841	GSK3B	Q05513	PRKCZ	S21	Q19R	19	Missense	proximal	-2	no	23.550	33.536	EPSD	TCGA	31.494	Gain
AGC_PKC_PKCi_PRKCZ_ST	P49841	GSK3B	Q05513	PRKCZ	S29	G34S	34	Missense	distal	5	no	40.769	40.622	EPSD	TCGA;COSMIC	31.494	Down-regulation
AGC_PKC_PKCi_PRKCZ_ST	P49841	GSK3B	Q05513	PRKCZ	S29	S25N	25	Missense	distal	-4	no	40.769	40.626	EPSD	TCGA;ICGC	31.494	Down-regulation
AGC_PKC_PKCi_PRKCZ_ST	P49841	GSK3B	Q05513	PRKCZ	S29	A22S	22	Missense	distal	-7	no	40.769	37.842	EPSD	TCGA;ICGC	31.494	Down-regulation
AGC_PKC_PKCi_PRKCZ_ST	P49841	GSK3B	Q05513	PRKCZ	S147	R148G	148	Missense	proximal	1	no	42.594	40.880	PhosphoSitePlus;EPSD	TCGA;ICGC;COSMIC	31.494	Down-regulation
AGC_PKC_PKCi_PRKCZ_ST	P49757	NUMB	Q05513	PRKCZ	S276	F277L	277	Missense	proximal	1	no	32.914	31.971	EPSD	TCGA;ICGC;COSMIC	31.494	Down-regulation
AGC_PKC_PKCi_PRKCZ_ST	P49757	NUMB	Q05513	PRKCZ	S276	Q270E	270	Missense	distal	-6	no	32.914	33.179	EPSD	TCGA;ICGC;COSMIC	31.494	Up-regulation
AGC_PKC_PKCi_PRKCZ_ST	P49757	NUMB	Q05513	PRKCZ	S295	R292C	292	Missense	distal	-3	no	34.788	14.755	EPSD	TCGA;ICGC;COSMIC	31.494	Loss
AGC_PKC_PKCi_PRKCZ_ST	P49757	NUMB	Q05513	PRKCZ	S295	R297H	297	Missense	proximal	2	no	34.788	30.635	EPSD	TCGA;ICGC;COSMIC	31.494	Loss
AGC_PKC_PKCi_PRKCZ_ST	P49757	NUMB	Q05513	PRKCZ	S295	E300G	300	Missense	distal	5	no	34.788	34.977	EPSD	TCGA;ICGC;COSMIC	31.494	Up-regulation
AGC_PKC_PKCi_PRKCZ_ST	P49757	NUMB	Q05513	PRKCZ	S295	R297C	297	Missense	proximal	2	no	34.788	23.599	EPSD	TCGA;ICGC;COSMIC	31.494	Loss
AGC_PKC_PKCi_PRKCZ_ST	P49757	NUMB	Q05513	PRKCZ	T304	R297H	297	Missense	distal	-7	no	32.742	29.392	EPSD	TCGA;ICGC;COSMIC	31.494	Loss
AGC_PKC_PKCi_PRKCZ_ST	P49757	NUMB	Q05513	PRKCZ	T304	E300G	300	Missense	distal	-4	no	32.742	32.552	EPSD	TCGA;ICGC;COSMIC	31.494	Down-regulation
AGC_PKC_PKCi_PRKCZ_ST	P49757	NUMB	Q05513	PRKCZ	T304	R297C	297	Missense	distal	-7	no	32.742	26.908	EPSD	TCGA;ICGC;COSMIC	31.494	Loss
AGC_PKC_PKCi_PRKCZ_ST	Q15831	STK11	Q05513	PRKCZ	S299	P294L	294	Missense	distal	-5	no	45.940	46.063	EPSD	TCGA;ICGC;COSMIC	31.494	Up-regulation
AGC_PKC_PKCi_PRKCZ_ST	Q15831	STK11	Q05513	PRKCZ	S299	R304W	304	Missense	distal	5	no	45.940	45.113	EPSD	TCGA;ICGC;COSMIC;CCLE	31.494	Down-regulation
AGC_PKC_PKCi_PRKCZ_ST	Q15831	STK11	Q05513	PRKCZ	S299	I303N	303	Missense	distal	4	no	45.940	53.275	EPSD	TCGA;ICGC;COSMIC	31.494	Up-regulation
AGC_PKC_PKCi_PRKCZ_ST	Q15831	STK11	Q05513	PRKCZ	S307	R304W	304	Missense	distal	-3	no	48.975	25.220	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC;CCLE	31.494	Loss
AGC_PKC_PKCi_PRKCZ_ST	Q15831	STK11	Q05513	PRKCZ	S307	I303N	303	Missense	distal	-4	no	48.975	48.752	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	31.494	Down-regulation
AGC_PKC_PKCi_PRKCZ_ST	Q15831	STK11	Q05513	PRKCZ	T336	R333S	333	Missense	distal	-3	no	42.436	29.010	EPSD	TCGA;ICGC;COSMIC	31.494	Loss
AGC_PKC_PKCi_PRKCZ_ST	O43315	AQP9	Q05513	PRKCZ	S11	L18M	18	Missense	distal	7	no	36.903	35.904	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	31.494	Down-regulation
AGC_PKC_PKCi_PRKCZ_ST	O43315	AQP9	Q05513	PRKCZ	S11	G9R	9	Missense	proximal	-2	no	36.903	47.597	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	31.494	Up-regulation
AGC_PKC_PKCi_PRKCZ_ST	O43315	AQP9	Q05513	PRKCZ	S11	K10E	10	Missense	proximal	-1	no	36.903	35.789	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	31.494	Down-regulation
AGC_PKC_PKCi_PRKCZ_ST	O43315	AQP9	Q05513	PRKCZ	S20	A23V	23	Missense	distal	3	no	32.078	22.686	EPSD	TCGA;ICGC;COSMIC	31.494	Loss
AGC_PKC_PKCi_PRKCZ_ST	O43315	AQP9	Q05513	PRKCZ	S20	L18M	18	Missense	proximal	-2	no	32.078	34.230	EPSD	TCGA;ICGC;COSMIC	31.494	Up-regulation
AGC_PKC_PKCi_PRKCZ_ST	O43315	AQP9	Q05513	PRKCZ	S21	A23V	23	Missense	proximal	2	no	44.259	43.898	EPSD	TCGA;ICGC;COSMIC	31.494	Down-regulation
AGC_PKC_PKCi_PRKCZ_ST	O43315	AQP9	Q05513	PRKCZ	S21	L18M	18	Missense	distal	-3	no	44.259	45.588	EPSD	TCGA;ICGC;COSMIC	31.494	Up-regulation
AGC_PKC_PKCi_PRKCZ_ST	O43315	AQP9	Q05513	PRKCZ	S222	P223S	223	Missense	proximal	1	no	50.080	49.525	PhosphoSitePlus;EPSD	TCGA;ICGC;COSMIC	31.494	Down-regulation
AGC_PKC_PKCi_PRKCZ_ST	P35580	MYH10	Q05513	PRKCZ	S85	P82R	82	Missense	distal	-3	no	21.717	40.588	EPSD	TCGA;ICGC;COSMIC	31.494	Gain
AGC_PKC_PKCi_PRKCZ_ST	P35580	MYH10	Q05513	PRKCZ	S201	R205S	205	Missense	distal	4	no	35.045	33.818	EPSD	TCGA;ICGC;COSMIC	31.494	Down-regulation
AGC_PKC_PKCi_PRKCZ_ST	P35580	MYH10	Q05513	PRKCZ	S201	R205K	205	Missense	distal	4	no	35.045	32.314	EPSD	TCGA;ICGC;COSMIC	31.494	Down-regulation
AGC_PKC_PKCi_PRKCZ_ST	P35580	MYH10	Q05513	PRKCZ	S201	L195F	195	Missense	distal	-6	no	35.045	35.123	EPSD	TCGA;ICGC;COSMIC	31.494	Up-regulation
AGC_PKC_PKCi_PRKCZ_ST	Q9UBS0	RPS6KB2	Q05513	PRKCZ	S377	A380T	380	Missense	distal	3	no	33.520	27.311	EPSD	TCGA;ICGC;COSMIC	31.494	Loss
AGC_PKC_PKCi_PRKCZ_ST	Q9UBS0	RPS6KB2	Q05513	PRKCZ	S377	A383G	383	Missense	distal	6	no	33.520	30.875	EPSD	TCGA;ICGC;COSMIC	31.494	Loss
AGC_PKC_PKCi_PRKCZ_ST	Q9UBS0	RPS6KB2	Q05513	PRKCZ	S416	R419W	419	Missense	distal	3	no	48.455	33.659	EPSD	TCGA;ICGC;COSMIC	31.494	Down-regulation
AGC_PKC_PKCi_PRKCZ_ST	Q9UBS0	RPS6KB2	Q05513	PRKCZ	S416	S410L	410	Missense	distal	-6	no	48.455	48.481	EPSD	TCGA;ICGC;COSMIC	31.494	Up-regulation
AGC_PKC_PKCi_PRKCZ_ST	P08047	SP1	Q05513	PRKCZ	S7	D5Y	5	Missense	proximal	-2	no	36.772	31.865	EPSD	TCGA;ICGC;COSMIC	31.494	Down-regulation
AGC_PKC_PKCi_PRKCZ_ST	P08047	SP1	Q05513	PRKCZ	S7	A13T	13	Missense	distal	6	no	36.772	33.828	EPSD	TCGA;ICGC;COSMIC	31.494	Down-regulation
AGC_PKC_PKCi_PRKCZ_ST	P08047	SP1	Q05513	PRKCZ	S45	T49A	49	Missense	distal	4	no	26.822	32.678	EPSD	TCGA;ICGC	31.494	Gain
AGC_PKC_PKCi_PRKCZ_ST	P08047	SP1	Q05513	PRKCZ	S73	S69N	69	Missense	distal	-4	no	40.983	40.840	EPSD	TCGA;ICGC;COSMIC	31.494	Down-regulation
AGC_PKC_PKCi_PRKCZ_ST	P08047	SP1	Q05513	PRKCZ	S73	C68R	68	Missense	distal	-5	no	40.983	37.398	EPSD	TCGA;ICGC;COSMIC	31.494	Down-regulation
AGC_PKC_PKCi_PRKCZ_ST	P08047	SP1	Q05513	PRKCZ	S73	P74S	74	Missense	proximal	1	no	40.983	40.428	EPSD	TCGA;ICGC;COSMIC	31.494	Down-regulation
AGC_PKC_PKCi_PRKCZ_ST	P08047	SP1	Q05513	PRKCZ	S73	S78N	78	Missense	distal	5	no	40.983	41.343	EPSD	TCGA;ICGC;COSMIC	31.494	Up-regulation
AGC_PKC_PKCi_PRKCZ_ST	P08047	SP1	Q05513	PRKCZ	T579	A580S	580	Missense	proximal	1	no	36.072	35.254	EPSD	TCGA;ICGC;COSMIC	31.494	Down-regulation
AGC_PKC_PKCi_PRKCZ_ST	P08047	SP1	Q05513	PRKCZ	T668	R666H	666	Missense	proximal	-2	no	40.198	31.345	PhosphoSitePlus;EPSD	TCGA;ICGC;COSMIC	31.494	Loss
AGC_PKC_PKCi_PRKCZ_ST	P08047	SP1	Q05513	PRKCZ	T668	S670L	670	Missense	proximal	2	no	40.198	42.757	PhosphoSitePlus;EPSD	TCGA;ICGC;COSMIC	31.494	Up-regulation
AGC_PKC_PKCi_PRKCZ_ST	P08047	SP1	Q05513	PRKCZ	T668	D671N	671	Missense	distal	3	no	40.198	37.921	PhosphoSitePlus;EPSD	TCGA;ICGC;COSMIC	31.494	Down-regulation
AGC_PKC_PKCi_PRKCZ_ST	P08047	SP1	Q05513	PRKCZ	T668	R669C	669	Missense	proximal	1	no	40.198	37.882	PhosphoSitePlus;EPSD	TCGA;ICGC;COSMIC	31.494	Down-regulation
AGC_PKC_PKCi_PRKCZ_ST	P08047	SP1	Q05513	PRKCZ	T681	H676L	676	Missense	distal	-5	no	39.768	41.948	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	31.494	Up-regulation
AGC_PKC_PKCi_PRKCZ_ST	P08047	SP1	Q05513	PRKCZ	S698	R697K	697	Missense	proximal	-1	no	32.339	31.840	EPSD	TCGA;ICGC;COSMIC	31.494	Down-regulation
AGC_PKC_PKCi_PRKCZ_ST	Q6STE5	SMARCD3	Q05513	PRKCZ	S247	R249H	249	Missense	proximal	2	no	36.922	32.768	PhosphoSitePlus	TCGA;COSMIC	31.494	Down-regulation
AGC_PKC_PKCi_PRKCZ_ST	Q6STE5	SMARCD3	Q05513	PRKCZ	S247	R242W	242	Missense	distal	-5	no	36.922	40.610	PhosphoSitePlus	TCGA;COSMIC	31.494	Up-regulation
AGC_PKC_PKCi_PRKCZ_ST	Q6STE5	SMARCD3	Q05513	PRKCZ	S428	Q421R	421	Missense	distal	-7	no	32.370	36.083	EPSD	TCGA;COSMIC	31.494	Up-regulation
AGC_PKC_PKCi_PRKCZ_ST	Q6STE5	SMARCD3	Q05513	PRKCZ	S428	R425C	425	Missense	distal	-3	no	32.370	12.336	EPSD	TCGA;COSMIC	31.494	Loss
AGC_PKC_PKCi_PRKCZ_ST	Q6STE5	SMARCD3	Q05513	PRKCZ	S477	R470C	470	Missense	distal	-7	no	42.121	36.287	EPSD	TCGA;COSMIC	31.494	Down-regulation
AGC_PKC_PKCi_PRKCZ_ST	P27448	MARK3	Q05513	PRKCZ	T211	Y218C	218	Missense	distal	7	no	41.358	42.301	EPSD	TCGA;COSMIC	31.494	Up-regulation
AGC_PKC_PKCi_PRKCZ_ST	P27448	MARK3	Q05513	PRKCZ	T211	S215C	215	Missense	distal	4	no	41.358	26.428	EPSD	TCGA	31.494	Loss
AGC_PKC_PKCi_PRKCZ_ST	P27448	MARK3	Q05513	PRKCZ	T211	T211M	211	Missense	central	0	yes	41.358	0.000	EPSD	TCGA;ICGC	31.494	Loss
AGC_PKC_PKCi_PRKCZ_ST	P27448	MARK3	Q05513	PRKCZ	T297	R295C	295	Missense	proximal	-2	no	45.866	32.076	EPSD	TCGA;ICGC	31.494	Down-regulation
AGC_PKC_PKCi_PRKCZ_ST	P27448	MARK3	Q05513	PRKCZ	S390	K386R	386	Missense	distal	-4	no	32.699	32.598	EPSD	TCGA;COSMIC	31.494	Down-regulation
AGC_PKC_PKCi_PRKCZ_ST	P27448	MARK3	Q05513	PRKCZ	S419	Y418C	418	Missense	proximal	-1	no	44.793	44.758	EPSD	TCGA;COSMIC	31.494	Down-regulation
AGC_PKC_PKCi_PRKCZ_ST	P27448	MARK3	Q05513	PRKCZ	T438	A431V	431	Missense	distal	-7	no	39.089	35.145	EPSD	TCGA;ICGC;COSMIC;GDSC;CCLE	31.494	Down-regulation
AGC_PKC_PKCi_PRKCZ_ST	P27448	MARK3	Q05513	PRKCZ	S451	S458I	458	Missense	distal	7	no	30.654	33.449	EPSD	TCGA;ICGC;COSMIC	31.494	Gain
AGC_PKC_PKCi_PRKCZ_ST	P27448	MARK3	Q05513	PRKCZ	S456	S456G	456	Missense	central	0	yes	33.771	0.000	EPSD	TCGA;ICGC;COSMIC	31.494	Loss
AGC_PKC_PKCi_PRKCZ_ST	P27448	MARK3	Q05513	PRKCZ	S456	S458I	458	Missense	proximal	2	no	33.771	31.151	EPSD	TCGA;ICGC;COSMIC	31.494	Loss
AGC_PKC_PKCi_PRKCZ_ST	P27448	MARK3	Q05513	PRKCZ	T507	R505P	505	Missense	proximal	-2	no	37.529	23.592	EPSD	TCGA;ICGC;COSMIC	31.494	Loss
AGC_PKC_PKCi_PRKCZ_ST	P27448	MARK3	Q05513	PRKCZ	T507	R505Q	505	Missense	proximal	-2	no	37.529	27.542	EPSD	TCGA;ICGC;COSMIC	31.494	Loss
AGC_PKC_PKCi_PRKCZ_ST	P27448	MARK3	Q05513	PRKCZ	S618	T613I	613	Missense	distal	-5	no	32.789	31.871	EPSD	TCGA;ICGC;COSMIC	31.494	Down-regulation
AGC_PKC_PKCi_PRKCZ_ST	P27448	MARK3	Q05513	PRKCZ	S643	V642A	642	Missense	proximal	-1	no	36.166	37.090	EPSD	TCGA;COSMIC	31.494	Up-regulation
AGC_PKC_PKCi_PRKCZ_ST	Q96RI1	NR1H4	Q05513	PRKCZ	S31	E28K	28	Missense	distal	-3	no	20.983	34.278	EPSD	TCGA;ICGC;COSMIC	31.494	Gain
AGC_PKC_PKCi_PRKCZ_ST	Q96RI1	NR1H4	Q05513	PRKCZ	S164	R163S	163	Missense	proximal	-1	no	42.692	41.590	EPSD	TCGA;COSMIC	31.494	Down-regulation
AGC_PKC_PKCi_PRKCZ_ST	Q96RI1	NR1H4	Q05513	PRKCZ	S164	R163T	163	Missense	proximal	-1	no	42.692	41.335	EPSD	TCGA;COSMIC	31.494	Down-regulation
AGC_PKC_PKCi_PRKCZ_ST	Q96RI1	NR1H4	Q05513	PRKCZ	S164	A169S	169	Missense	distal	5	no	42.692	42.410	EPSD	TCGA;COSMIC	31.494	Down-regulation
AGC_PKC_PKCi_PRKCZ_ST	Q96RI1	NR1H4	Q05513	PRKCZ	S164	R162M	162	Missense	proximal	-2	no	42.692	33.284	EPSD	TCGA;COSMIC	31.494	Down-regulation
AGC_PKC_PKCi_PRKCZ_ST	Q96RI1	NR1H4	Q05513	PRKCZ	S164	R162S	162	Missense	proximal	-2	no	42.692	30.601	EPSD	TCGA;COSMIC	31.494	Loss
AGC_PKC_PKCi_PRKCZ_ST	Q96RI1	NR1H4	Q05513	PRKCZ	S164	G159D	159	Missense	distal	-5	no	42.692	42.649	EPSD	TCGA	31.494	Down-regulation
AGC_PKC_PKCi_PRKCZ_ST	Q96RI1	NR1H4	Q05513	PRKCZ	S164	R163I	163	Missense	proximal	-1	no	42.692	41.108	EPSD	TCGA;COSMIC	31.494	Down-regulation
AGC_PKC_PKCi_PRKCZ_ST	Q96RI1	NR1H4	Q05513	PRKCZ	S164	A169T	169	Missense	distal	5	no	42.692	42.419	EPSD	TCGA	31.494	Down-regulation
AGC_PKC_PKCi_PRKCZ_ST	Q96RI1	NR1H4	Q05513	PRKCZ	T456	N458S	458	Missense	proximal	2	no	37.875	37.748	EPSD	TCGA;COSMIC	31.494	Down-regulation
AGC_PKC_PKCi_PRKCZ_ST	Q96RI1	NR1H4	Q05513	PRKCZ	T456	A462T	462	Missense	distal	6	no	37.875	34.930	EPSD	TCGA;CCLE	31.494	Down-regulation
AGC_PKC_PKCi_PRKCZ_ST	Q96RI1	NR1H4	Q05513	PRKCZ	S467	D472Y	472	Missense	distal	5	no	45.617	45.480	EPSD	TCGA;COSMIC	31.494	Down-regulation
AGC_PKC_PKCi_PRKCZ_ST	Q96RI1	NR1H4	Q05513	PRKCZ	S467	M466I	466	Missense	proximal	-1	no	45.617	44.816	EPSD	TCGA;COSMIC	31.494	Down-regulation
AGC_PKC_PKCi_PRKCZ_ST	Q96RI1	NR1H4	Q05513	PRKCZ	S467	A462T	462	Missense	distal	-5	no	45.617	46.960	EPSD	TCGA;CCLE	31.494	Up-regulation
AGC_PKC_PKCi_PRKCZ_ST	Q96RI1	NR1H4	Q05513	PRKCZ	S467	N471S	471	Missense	distal	4	no	45.617	45.402	EPSD	TCGA;COSMIC	31.494	Down-regulation
AGC_PKC_PKCi_PRKCZ_ST	Q96A00	PPP1R14A	Q05513	PRKCZ	T38	R36C	36	Missense	proximal	-2	no	42.752	28.961	PhosphoSitePlus	TCGA;ICGC;COSMIC	31.494	Loss
AGC_PKC_PKCi_PRKCZ_ST	Q96A00	PPP1R14A	Q05513	PRKCZ	T38	R44W	44	Missense	distal	6	no	42.752	35.017	PhosphoSitePlus	TCGA;ICGC;COSMIC	31.494	Down-regulation
AGC_PKC_PKCi_PRKCZ_ST	Q96A00	PPP1R14A	Q05513	PRKCZ	S130	P129T	129	Missense	proximal	-1	no	36.539	37.140	EPSD	TCGA;COSMIC	31.494	Up-regulation
AGC_PKC_PKCi_PRKCZ_ST	Q96A00	PPP1R14A	Q05513	PRKCZ	S136	L138P	138	Missense	proximal	2	no	32.355	27.278	EPSD	TCGA;ICGC	31.494	Loss
AGC_PKC_PKCi_PRKCZ_ST	Q96A00	PPP1R14A	Q05513	PRKCZ	S136	P129T	129	Missense	distal	-7	no	32.355	34.995	EPSD	TCGA;COSMIC	31.494	Up-regulation
AGC_PKC_PKCi_PRKCZ_ST	P35568	IRS1	Q05513	PRKCZ	S24	R20C	20	Missense	distal	-4	no	37.310	37.973	EPSD	TCGA;ICGC;COSMIC	31.494	Up-regulation
AGC_PKC_PKCi_PRKCZ_ST	P35568	IRS1	Q05513	PRKCZ	S24	R20H	20	Missense	distal	-4	no	37.310	37.525	EPSD	TCGA;ICGC	31.494	Up-regulation
AGC_PKC_PKCi_PRKCZ_ST	P35568	IRS1	Q05513	PRKCZ	S268	E263K	263	Missense	distal	-5	no	36.016	35.342	EPSD	TCGA;ICGC;COSMIC	31.494	Down-regulation
AGC_PKC_PKCi_PRKCZ_ST	P35568	IRS1	Q05513	PRKCZ	S268	K269N	269	Missense	proximal	1	no	36.016	35.748	EPSD	TCGA;ICGC;COSMIC	31.494	Down-regulation
AGC_PKC_PKCi_PRKCZ_ST	P35568	IRS1	Q05513	PRKCZ	S268	P266S	266	Missense	proximal	-2	no	36.016	37.862	EPSD	TCGA;ICGC;COSMIC	31.494	Up-regulation
AGC_PKC_PKCi_PRKCZ_ST	P35568	IRS1	Q05513	PRKCZ	S268	S261I	261	Missense	distal	-7	no	36.016	33.712	EPSD	TCGA;ICGC;COSMIC	31.494	Down-regulation
AGC_PKC_PKCi_PRKCZ_ST	P35568	IRS1	Q05513	PRKCZ	S268	N275S	275	Missense	distal	7	no	36.016	34.879	EPSD	TCGA;ICGC;COSMIC	31.494	Down-regulation
AGC_PKC_PKCi_PRKCZ_ST	P35568	IRS1	Q05513	PRKCZ	S270	E263K	263	Missense	distal	-7	no	26.715	32.535	EPSD	TCGA;ICGC;COSMIC	31.494	Gain
AGC_PKC_PKCi_PRKCZ_ST	P35568	IRS1	Q05513	PRKCZ	S307	A314G	314	Missense	distal	7	no	35.352	37.311	EPSD	TCGA;ICGC;COSMIC	31.494	Up-regulation
AGC_PKC_PKCi_PRKCZ_ST	P35568	IRS1	Q05513	PRKCZ	S323	S330N	330	Missense	distal	7	no	31.473	32.611	PhosphoSitePlus;EPSD	TCGA;ICGC;COSMIC	31.494	Gain
AGC_PKC_PKCi_PRKCZ_ST	P35568	IRS1	Q05513	PRKCZ	S323	P321L	321	Missense	proximal	-2	no	31.473	33.851	PhosphoSitePlus;EPSD	TCGA;ICGC;COSMIC	31.494	Gain
AGC_PKC_PKCi_PRKCZ_ST	P35568	IRS1	Q05513	PRKCZ	S362	A363D	363	Missense	proximal	1	no	36.695	36.199	EPSD	TCGA;ICGC;COSMIC	31.494	Down-regulation
AGC_PKC_PKCi_PRKCZ_ST	P35568	IRS1	Q05513	PRKCZ	S362	A356T	356	Missense	distal	-6	no	36.695	36.843	EPSD	TCGA;ICGC;COSMIC	31.494	Up-regulation
AGC_PKC_PKCi_PRKCZ_ST	P35568	IRS1	Q05513	PRKCZ	S362	A363T	363	Missense	proximal	1	no	36.695	36.086	EPSD	TCGA;ICGC;COSMIC	31.494	Down-regulation
AGC_PKC_PKCi_PRKCZ_ST	P35568	IRS1	Q05513	PRKCZ	S362	R360W	360	Missense	proximal	-2	no	36.695	18.522	EPSD	TCGA;ICGC;CCLE	31.494	Loss
AGC_PKC_PKCi_PRKCZ_ST	P35568	IRS1	Q05513	PRKCZ	S362	H359R	359	Missense	distal	-3	no	36.695	45.124	EPSD	TCGA;ICGC	31.494	Up-regulation
AGC_PKC_PKCi_PRKCZ_ST	P35568	IRS1	Q05513	PRKCZ	S413	R411Q	411	Missense	proximal	-2	no	47.563	37.576	EPSD	TCGA;ICGC	31.494	Down-regulation
AGC_PKC_PKCi_PRKCZ_ST	P35568	IRS1	Q05513	PRKCZ	S441	F438V	438	Missense	distal	-3	no	36.739	40.143	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	31.494	Up-regulation
AGC_PKC_PKCi_PRKCZ_ST	P35568	IRS1	Q05513	PRKCZ	S441	V445I	445	Missense	distal	4	no	36.739	39.196	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	31.494	Up-regulation
AGC_PKC_PKCi_PRKCZ_ST	P35568	IRS1	Q05513	PRKCZ	S441	R443H	443	Missense	proximal	2	no	36.739	32.586	EPSD;PhosphoSitePlus	TCGA;ICGC	31.494	Down-regulation
AGC_PKC_PKCi_PRKCZ_ST	P35568	IRS1	Q05513	PRKCZ	S503	T498I	498	Missense	distal	-5	no	33.842	32.924	EPSD	TCGA;ICGC;COSMIC	31.494	Down-regulation
AGC_PKC_PKCi_PRKCZ_ST	P35568	IRS1	Q05513	PRKCZ	S503	P504A	504	Missense	proximal	1	no	33.842	34.105	EPSD	TCGA;ICGC;COSMIC	31.494	Up-regulation
AGC_PKC_PKCi_PRKCZ_ST	P35568	IRS1	Q05513	PRKCZ	T525	R520W	520	Missense	distal	-5	no	32.377	36.065	EPSD	TCGA;ICGC;COSMIC	31.494	Up-regulation
AGC_PKC_PKCi_PRKCZ_ST	P35568	IRS1	Q05513	PRKCZ	T525	R522Q	522	Missense	distal	-3	no	32.377	20.490	EPSD	TCGA;ICGC;COSMIC	31.494	Loss
AGC_PKC_PKCi_PRKCZ_ST	P35568	IRS1	Q05513	PRKCZ	T525	R520Q	520	Missense	distal	-5	no	32.377	34.788	EPSD	TCGA;ICGC;COSMIC	31.494	Up-regulation
AGC_PKC_PKCi_PRKCZ_ST	P35568	IRS1	Q05513	PRKCZ	S574	S581Y	581	Missense	distal	7	no	33.848	36.212	EPSD	TCGA;ICGC;COSMIC	31.494	Up-regulation
AGC_PKC_PKCi_PRKCZ_ST	P35568	IRS1	Q05513	PRKCZ	S574	P569L	569	Missense	distal	-5	no	33.848	33.972	EPSD	TCGA;ICGC;COSMIC	31.494	Up-regulation
AGC_PKC_PKCi_PRKCZ_ST	P35568	IRS1	Q05513	PRKCZ	S604	H607R	607	Missense	distal	3	no	29.334	35.564	EPSD	TCGA;ICGC	31.494	Gain
AGC_PKC_PKCi_PRKCZ_ST	P35568	IRS1	Q05513	PRKCZ	T851	A856T	856	Missense	distal	5	no	31.817	31.544	EPSD	TCGA;ICGC;COSMIC	31.494	Down-regulation
AGC_PKC_PKCi_PRKCZ_ST	P35568	IRS1	Q05513	PRKCZ	T851	R857W	857	Missense	distal	6	no	31.817	24.082	EPSD	TCGA;ICGC;COSMIC	31.494	Loss
AGC_PKC_PKCi_PRKCZ_ST	P35568	IRS1	Q05513	PRKCZ	S984	R986W	986	Missense	proximal	2	no	32.534	18.197	EPSD	TCGA;ICGC;COSMIC;GDSC;CCLE	31.494	Loss
AGC_PKC_PKCi_PRKCZ_ST	P35568	IRS1	Q05513	PRKCZ	S1216	S1223G	1223	Missense	distal	7	no	29.551	31.908	EPSD	TCGA;ICGC;COSMIC	31.494	Gain
AGC_PKC_PKCi_PRKCZ_ST	P35568	IRS1	Q05513	PRKCZ	S1218	S1223G	1223	Missense	distal	5	no	40.982	41.129	EPSD	TCGA;ICGC;COSMIC	31.494	Up-regulation
AGC_PKC_PKCi_PRKCZ_ST	P35568	IRS1	Q05513	PRKCZ	T1219	S1223G	1223	Missense	distal	4	no	41.313	37.110	EPSD	TCGA;ICGC;COSMIC	31.494	Down-regulation
AGC_PKC_PKCi_PRKCZ_ST	P35568	IRS1	Q05513	PRKCZ	S1222	S1223G	1223	Missense	proximal	1	no	41.403	42.128	EPSD	TCGA;ICGC;COSMIC	31.494	Up-regulation
AGC_PKC_PKCi_PRKCZ_ST	P35568	IRS1	Q05513	PRKCZ	S1223	S1223G	1223	Missense	central	0	yes	49.574	0.000	EPSD	TCGA;ICGC;COSMIC	31.494	Loss
AGC_PKC_PKCi_PRKCZ_ST	P35568	IRS1	Q05513	PRKCZ	S1227	S1223G	1223	Missense	distal	-4	no	44.292	44.232	EPSD	TCGA;ICGC;COSMIC	31.494	Down-regulation
AGC_PKC_PKCi_PRKCZ_ST	P35568	IRS1	Q05513	PRKCZ	S1227	S1233G	1233	Missense	distal	6	no	44.292	43.210	EPSD	TCGA;ICGC;COSMIC	31.494	Down-regulation
AGC_PKC_PKCi_PRKCZ_ST	Q8N2W9	PIAS4	Q05513	PRKCZ	S18	R16Q	16	Missense	proximal	-2	no	41.522	31.536	PhosphoSitePlus	TCGA;ICGC;COSMIC	31.494	Down-regulation
AGC_PKC_PKCi_PRKCZ_ST	Q8N2W9	PIAS4	Q05513	PRKCZ	S18	M11I	11	Missense	distal	-7	no	41.522	37.225	PhosphoSitePlus	TCGA;ICGC;COSMIC	31.494	Down-regulation
AGC_PKC_PKCi_PRKCZ_ST	Q8N2W9	PIAS4	Q05513	PRKCZ	S18	M13L	13	Missense	distal	-5	no	41.522	44.095	PhosphoSitePlus	TCGA;ICGC;COSMIC	31.494	Up-regulation
AGC_PKC_PKCi_PRKCZ_ST	Q8N2W9	PIAS4	Q05513	PRKCZ	S384	G381R	381	Missense	distal	-3	no	19.428	33.666	EPSD	TCGA;ICGC;COSMIC	31.494	Gain
AGC_PKC_PKCi_PRKCZ_ST	Q8N2W9	PIAS4	Q05513	PRKCZ	S416	P417L	417	Missense	proximal	1	no	37.456	37.208	EPSD	TCGA;ICGC;COSMIC	31.494	Down-regulation
AGC_PKC_PKCi_PRKCZ_ST	Q8N2W9	PIAS4	Q05513	PRKCZ	S416	Q418H	418	Missense	proximal	2	no	37.456	41.172	EPSD	TCGA;ICGC;COSMIC	31.494	Up-regulation
AGC_PKC_PKCi_PRKCZ_ST	P35222	CTNNB1	Q05513	PRKCZ	S222	R225H	225	Missense	distal	3	no	40.754	34.524	EPSD	TCGA;COSMIC	31.494	Down-regulation
AGC_PKC_PKCi_PRKCZ_ST	P35222	CTNNB1	Q05513	PRKCZ	S222	E226D	226	Missense	distal	4	no	40.754	38.194	EPSD	TCGA;COSMIC	31.494	Down-regulation
AGC_PKC_PKCi_PRKCZ_ST	P35222	CTNNB1	Q05513	PRKCZ	S222	A215T	215	Missense	distal	-7	no	40.754	38.625	EPSD	TCGA;COSMIC	31.494	Down-regulation
AGC_PKC_PKCi_PRKCZ_ST	P35222	CTNNB1	Q05513	PRKCZ	T393	E399A	399	Missense	distal	6	no	31.311	33.233	EPSD	TCGA;COSMIC	31.494	Gain
AGC_PKC_PKCi_PRKCZ_ST	P35222	CTNNB1	Q05513	PRKCZ	T393	E396D	396	Missense	distal	3	no	31.311	36.446	EPSD	TCGA	31.494	Gain
AGC_PKC_PKCi_PRKCZ_ST	P35222	CTNNB1	Q05513	PRKCZ	T472	R469H	469	Missense	distal	-3	no	35.794	27.365	EPSD	TCGA;COSMIC	31.494	Loss
AGC_PKC_PKCi_PRKCZ_ST	P35222	CTNNB1	Q05513	PRKCZ	T472	R474Q	474	Missense	proximal	2	no	35.794	27.925	EPSD	TCGA;GDSC;CCLE	31.494	Loss
AGC_PKC_PKCi_PRKCZ_ST	P35222	CTNNB1	Q05513	PRKCZ	S473	R469H	469	Missense	distal	-4	no	34.823	35.038	EPSD	TCGA;COSMIC	31.494	Up-regulation
AGC_PKC_PKCi_PRKCZ_ST	P35222	CTNNB1	Q05513	PRKCZ	S473	R474Q	474	Missense	proximal	1	no	34.823	32.549	EPSD	TCGA;GDSC;CCLE	31.494	Down-regulation
AGC_PKC_PKCi_PRKCZ_ST	P35222	CTNNB1	Q05513	PRKCZ	T547	R542H	542	Missense	distal	-5	no	41.763	43.137	EPSD	TCGA;COSMIC	31.494	Up-regulation
AGC_PKC_PKCi_PRKCZ_ST	P35222	CTNNB1	Q05513	PRKCZ	T547	M553V	553	Missense	distal	6	no	41.763	41.023	EPSD	TCGA;COSMIC	31.494	Down-regulation
AGC_PKC_PKCi_PRKCZ_ST	P35222	CTNNB1	Q05513	PRKCZ	T547	V541A	541	Missense	distal	-6	no	41.763	41.400	EPSD	TCGA;COSMIC	31.494	Down-regulation
AGC_PKC_PKCi_PRKCZ_ST	P35222	CTNNB1	Q05513	PRKCZ	S552	M553V	553	Missense	proximal	1	no	34.285	33.883	EPSD	TCGA;COSMIC	31.494	Down-regulation
AGC_PKC_PKCi_PRKCZ_ST	P35222	CTNNB1	Q05513	PRKCZ	S680	F683Y	683	Missense	distal	3	no	27.933	32.559	EPSD	TCGA;COSMIC	31.494	Gain
AGC_PKC_PKCi_PRKCZ_ST	P35612	ADD2	Q05513	PRKCZ	T5	E3K	3	Missense	proximal	-2	no	22.760	32.654	EPSD	TCGA;ICGC;COSMIC;GDSC;CCLE	31.494	Gain
AGC_PKC_PKCi_PRKCZ_ST	P35612	ADD2	Q05513	PRKCZ	S25	Y31C	31	Missense	distal	6	no	38.606	40.246	EPSD	TCGA;ICGC;COSMIC	31.494	Up-regulation
AGC_PKC_PKCi_PRKCZ_ST	P35612	ADD2	Q05513	PRKCZ	S25	E26K	26	Missense	proximal	1	no	38.606	40.547	EPSD	TCGA;ICGC;COSMIC	31.494	Up-regulation
AGC_PKC_PKCi_PRKCZ_ST	P35612	ADD2	Q05513	PRKCZ	S25	P19L	19	Missense	distal	-6	no	38.606	38.354	EPSD	TCGA;ICGC;COSMIC	31.494	Down-regulation
AGC_PKC_PKCi_PRKCZ_ST	P35612	ADD2	Q05513	PRKCZ	S472	R478C	478	Missense	distal	6	no	40.395	33.384	EPSD	TCGA;ICGC;COSMIC	31.494	Down-regulation
AGC_PKC_PKCi_PRKCZ_ST	P35612	ADD2	Q05513	PRKCZ	S472	E469K	469	Missense	distal	-3	no	40.395	53.690	EPSD	TCGA;ICGC;COSMIC	31.494	Up-regulation
AGC_PKC_PKCi_PRKCZ_ST	P35612	ADD2	Q05513	PRKCZ	S472	S471Y	471	Missense	proximal	-1	no	40.395	39.593	EPSD	TCGA;ICGC;COSMIC	31.494	Down-regulation
AGC_PKC_PKCi_PRKCZ_ST	P35612	ADD2	Q05513	PRKCZ	S472	P476L	476	Missense	distal	4	no	40.395	36.609	EPSD	TCGA;ICGC;COSMIC	31.494	Down-regulation
AGC_PKC_PKCi_PRKCZ_ST	P35612	ADD2	Q05513	PRKCZ	S472	M475V	475	Missense	distal	3	no	40.395	35.120	EPSD	TCGA;ICGC;COSMIC	31.494	Down-regulation
AGC_PKC_PKCi_PRKCZ_ST	P35612	ADD2	Q05513	PRKCZ	S472	R478H	478	Missense	distal	6	no	40.395	39.352	EPSD	TCGA;ICGC	31.494	Down-regulation
AGC_PKC_PKCi_PRKCZ_ST	P35612	ADD2	Q05513	PRKCZ	T631	A634V	634	Missense	distal	3	no	37.410	28.018	EPSD	TCGA;ICGC	31.494	Loss
AGC_PKC_PKCi_PRKCZ_ST	P35612	ADD2	Q05513	PRKCZ	T631	E630K	630	Missense	proximal	-1	no	37.410	38.525	EPSD	TCGA;ICGC;COSMIC	31.494	Up-regulation
AGC_PKC_PKCi_PRKCZ_ST	P35612	ADD2	Q05513	PRKCZ	T631	K628N	628	Missense	distal	-3	no	37.410	29.654	EPSD	TCGA;ICGC	31.494	Loss
AGC_PKC_PKCi_PRKCZ_ST	P35612	ADD2	Q05513	PRKCZ	S667	E660K	660	Missense	distal	-7	no	27.407	33.227	EPSD	TCGA;ICGC;COSMIC	31.494	Gain
AGC_PKC_PKCi_PRKCZ_ST	P35612	ADD2	Q05513	PRKCZ	S703	K707N	707	Missense	distal	4	no	32.105	33.824	EPSD	TCGA;ICGC;COSMIC	31.494	Up-regulation
AGC_PKC_PKCi_PRKCZ_ST	P35612	ADD2	Q05513	PRKCZ	S713	K707N	707	Missense	distal	-6	no	51.158	51.416	PhosphoSitePlus	TCGA;ICGC;COSMIC	31.494	Up-regulation
AGC_PKC_PKCi_PRKCZ_ST	P35612	ADD2	Q05513	PRKCZ	S713	P712L	712	Missense	proximal	-1	no	51.158	51.319	PhosphoSitePlus	TCGA;ICGC;COSMIC	31.494	Up-regulation
AGC_PKC_PKCi_PRKCZ_ST	P35612	ADD2	Q05513	PRKCZ	S718	P712L	712	Missense	distal	-6	no	50.333	50.081	EPSD	TCGA;ICGC;COSMIC	31.494	Down-regulation
AGC_PKC_PKCi_PRKCZ_ST	P35611	ADD1	Q05513	PRKCZ	S59	P65H	65	Missense	distal	6	no	36.987	42.069	EPSD	TCGA;ICGC;COSMIC	31.494	Up-regulation
AGC_PKC_PKCi_PRKCZ_ST	P35611	ADD1	Q05513	PRKCZ	S358	R354C	354	Missense	distal	-4	no	33.099	33.762	EPSD	TCGA;ICGC;COSMIC	31.494	Up-regulation
AGC_PKC_PKCi_PRKCZ_ST	P35611	ADD1	Q05513	PRKCZ	S436	Q438H	438	Missense	proximal	2	no	28.183	31.899	EPSD	TCGA;ICGC;COSMIC	31.494	Gain
AGC_PKC_PKCi_PRKCZ_ST	P35611	ADD1	Q05513	PRKCZ	S436	Q438R	438	Missense	proximal	2	no	28.183	36.053	EPSD	TCGA;ICGC;COSMIC	31.494	Gain
AGC_PKC_PKCi_PRKCZ_ST	Q9UJZ1	STOML2	Q05513	PRKCZ	S21	P25A	25	Missense	distal	4	no	37.672	45.304	EPSD	TCGA;ICGC;COSMIC;CCLE	31.494	Up-regulation
AGC_PKC_PKCi_PRKCZ_ST	Q9UJZ1	STOML2	Q05513	PRKCZ	S29	P25A	25	Missense	distal	-4	no	32.184	31.550	EPSD	TCGA;ICGC;COSMIC;CCLE	31.494	Down-regulation
AGC_PKC_PKCi_PRKCZ_ST	Q9UJZ1	STOML2	Q05513	PRKCZ	S29	T36N	36	Missense	distal	7	no	32.184	34.520	EPSD	TCGA;ICGC;COSMIC	31.494	Up-regulation
AGC_PKC_PKCi_PRKCZ_ST	Q9UJZ1	STOML2	Q05513	PRKCZ	S142	E149K	149	Missense	distal	7	no	34.784	34.506	EPSD	TCGA;ICGC;COSMIC	31.494	Down-regulation
AGC_PKC_PKCi_PRKCZ_ST	Q9UJZ1	STOML2	Q05513	PRKCZ	S142	G139S	139	Missense	distal	-3	no	34.784	35.596	EPSD	TCGA;ICGC	31.494	Up-regulation
AGC_PKC_PKCi_PRKCZ_ST	Q9UJZ1	STOML2	Q05513	PRKCZ	S345	E349Q	349	Missense	distal	4	no	39.022	40.203	EPSD	TCGA;ICGC;COSMIC	31.494	Up-regulation
AGC_PKC_PKCi_PRKCZ_ST	P55211	CASP9	Q05513	PRKCZ	S144	G137S	137	Missense	distal	-7	no	47.095	46.618	PhosphoSitePlus	TCGA;ICGC;COSMIC	31.494	Down-regulation
AGC_PKC_PKCi_PRKCZ_ST	P55211	CASP9	Q05513	PRKCZ	S195	R193H	193	Missense	proximal	-2	no	37.525	28.672	EPSD	TCGA;ICGC;COSMIC	31.494	Loss
AGC_PKC_PKCi_PRKCZ_ST	P55211	CASP9	Q05513	PRKCZ	S195	R191W	191	Missense	distal	-4	no	37.525	38.245	EPSD	TCGA;ICGC;COSMIC	31.494	Up-regulation
AGC_PKC_PKCi_PRKCZ_ST	P55211	CASP9	Q05513	PRKCZ	S195	R191Q	191	Missense	distal	-4	no	37.525	37.711	EPSD	TCGA	31.494	Up-regulation
AGC_PKC_PKCi_PRKCZ_ST	P55211	CASP9	Q05513	PRKCZ	S195	E188D	188	Missense	distal	-7	no	37.525	41.248	EPSD	TCGA;ICGC	31.494	Up-regulation
AGC_PKC_PKCi_PRKCZ_ST	P78563	ADARB1	Q05513	PRKCZ	S13	R20C	20	Missense	distal	7	no	30.304	33.567	EPSD	TCGA;ICGC;COSMIC	31.494	Gain
AGC_PKC_PKCi_PRKCZ_ST	P78563	ADARB1	Q05513	PRKCZ	S26	P33L	33	Missense	distal	7	no	33.331	30.802	EPSD	TCGA;ICGC;COSMIC	31.494	Loss
AGC_PKC_PKCi_PRKCZ_ST	P78563	ADARB1	Q05513	PRKCZ	S26	R20C	20	Missense	distal	-6	no	33.331	33.942	EPSD	TCGA;ICGC;COSMIC	31.494	Up-regulation
AGC_PKC_PKCi_PRKCZ_ST	P78563	ADARB1	Q05513	PRKCZ	S31	P33L	33	Missense	proximal	2	no	32.318	37.395	EPSD	TCGA;ICGC;COSMIC	31.494	Up-regulation
AGC_PKC_PKCi_PRKCZ_ST	P78563	ADARB1	Q05513	PRKCZ	T73	P76S	76	Missense	distal	3	no	29.955	36.525	EPSD	TCGA;ICGC;COSMIC	31.494	Gain
AGC_PKC_PKCi_PRKCZ_ST	P78563	ADARB1	Q05513	PRKCZ	S429	Q427E	427	Missense	proximal	-2	no	36.197	31.064	EPSD	TCGA;ICGC;COSMIC	31.494	Loss
AGC_PKC_PKCi_PRKCZ_ST	P78563	ADARB1	Q05513	PRKCZ	S429	S429A	429	Missense	central	0	yes	36.197	0.000	EPSD	TCGA;ICGC;COSMIC	31.494	Loss
AGC_PKC_PKCi_PRKCZ_ST	P78563	ADARB1	Q05513	PRKCZ	S429	G433V	433	Missense	distal	4	no	36.197	30.824	EPSD	TCGA;ICGC;COSMIC	31.494	Loss
AGC_PKC_PKCi_PRKCZ_ST	Q9UIQ6	LNPEP	Q05513	PRKCZ	S86	T93A	93	Missense	distal	7	no	41.194	42.792	EPSD	TCGA;ICGC;COSMIC	31.494	Up-regulation
AGC_PKC_PKCi_PRKCZ_ST	Q9UIQ6	LNPEP	Q05513	PRKCZ	S86	R89Q	89	Missense	distal	3	no	41.194	35.597	EPSD	TCGA;ICGC;COSMIC	31.494	Down-regulation
AGC_PKC_PKCi_PRKCZ_ST	Q9UIQ6	LNPEP	Q05513	PRKCZ	S91	T93A	93	Missense	proximal	2	no	40.113	41.725	EPSD	TCGA;ICGC;COSMIC	31.494	Up-regulation
AGC_PKC_PKCi_PRKCZ_ST	Q9UIQ6	LNPEP	Q05513	PRKCZ	S91	R89Q	89	Missense	proximal	-2	no	40.113	30.127	EPSD	TCGA;ICGC;COSMIC	31.494	Loss
AGC_PKC_PKCi_PRKCZ_ST	Q9UIQ6	LNPEP	Q05513	PRKCZ	S98	T93A	93	Missense	distal	-5	no	39.028	37.686	EPSD	TCGA;ICGC;COSMIC	31.494	Down-regulation
AGC_PKC_PKCi_PRKCZ_ST	Q9UIQ6	LNPEP	Q05513	PRKCZ	S98	P99T	99	Missense	proximal	1	no	39.028	38.682	EPSD	TCGA;ICGC	31.494	Down-regulation
AGC_PKC_PKCi_PRKCZ_ST	Q9UIQ6	LNPEP	Q05513	PRKCZ	S666	L673V	673	Missense	distal	7	no	43.902	43.267	EPSD	TCGA;ICGC;COSMIC	31.494	Down-regulation
AGC_PKC_PKCi_PRKCZ_ST	Q15466	NR0B2	Q05513	PRKCZ	T55	H53D	53	Missense	proximal	-2	no	32.103	34.243	PhosphoSitePlus	TCGA;ICGC;COSMIC	31.494	Up-regulation
AGC_PKC_PKCi_PRKCZ_ST	Q15466	NR0B2	Q05513	PRKCZ	T55	R54H	54	Missense	proximal	-1	no	32.103	31.304	PhosphoSitePlus	TCGA;ICGC	31.494	Loss
AGC_PKC_PKCi_PRKCZ_ST	P28329	CHAT	Q05513	PRKCZ	S125	S126R	126	Missense	proximal	1	no	38.571	41.010	EPSD	TCGA;COSMIC	31.494	Up-regulation
AGC_PKC_PKCi_PRKCZ_ST	P28329	CHAT	Q05513	PRKCZ	S125	E128Q	128	Missense	distal	3	no	38.571	43.146	EPSD	TCGA;COSMIC	31.494	Up-regulation
AGC_PKC_PKCi_PRKCZ_ST	P28329	CHAT	Q05513	PRKCZ	S125	G130R	130	Missense	distal	5	no	38.571	39.010	EPSD	TCGA;COSMIC	31.494	Up-regulation
AGC_PKC_PKCi_PRKCZ_ST	P28329	CHAT	Q05513	PRKCZ	S125	G130E	130	Missense	distal	5	no	38.571	38.383	EPSD	TCGA;COSMIC	31.494	Down-regulation
AGC_PKC_PKCi_PRKCZ_ST	P28329	CHAT	Q05513	PRKCZ	S125	A121V	121	Missense	distal	-4	no	38.571	38.992	EPSD	TCGA;COSMIC	31.494	Up-regulation
AGC_PKC_PKCi_PRKCZ_ST	P28329	CHAT	Q05513	PRKCZ	S125	T123N	123	Missense	proximal	-2	no	38.571	37.011	EPSD	TCGA	31.494	Down-regulation
AGC_PKC_PKCi_PRKCZ_ST	P28329	CHAT	Q05513	PRKCZ	T373	D379Y	379	Missense	distal	6	no	42.238	35.046	EPSD	TCGA;COSMIC	31.494	Down-regulation
AGC_PKC_PKCi_PRKCZ_ST	P28329	CHAT	Q05513	PRKCZ	T373	S377L	377	Missense	distal	4	no	42.238	31.416	EPSD	TCGA;COSMIC	31.494	Loss
AGC_PKC_PKCi_PRKCZ_ST	P28329	CHAT	Q05513	PRKCZ	S377	D379Y	379	Missense	proximal	2	no	38.172	32.104	EPSD	TCGA;COSMIC	31.494	Down-regulation
AGC_PKC_PKCi_PRKCZ_ST	P28329	CHAT	Q05513	PRKCZ	S377	S377L	377	Missense	central	0	yes	38.172	0.000	EPSD	TCGA;COSMIC	31.494	Loss
AGC_PKC_PKCi_PRKCZ_ST	P28329	CHAT	Q05513	PRKCZ	S464	H460L	460	Missense	distal	-4	no	31.482	31.828	EPSD	TCGA;COSMIC	31.494	Gain
AGC_PKC_PKCi_PRKCZ_ST	P28329	CHAT	Q05513	PRKCZ	S464	L457M	457	Missense	distal	-7	no	31.482	33.082	EPSD	TCGA;COSMIC	31.494	Gain
AGC_PKC_PKCi_PRKCZ_ST	P28329	CHAT	Q05513	PRKCZ	S465	H460L	460	Missense	distal	-5	no	35.215	37.395	EPSD	TCGA;COSMIC	31.494	Up-regulation
AGC_PKC_PKCi_PRKCZ_ST	P28329	CHAT	Q05513	PRKCZ	S465	R470Q	470	Missense	distal	5	no	35.215	34.588	EPSD	TCGA;COSMIC	31.494	Down-regulation
AGC_PKC_PKCi_PRKCZ_ST	P28329	CHAT	Q05513	PRKCZ	S465	R466K	466	Missense	proximal	1	no	35.215	33.568	EPSD	TCGA;COSMIC	31.494	Down-regulation
AGC_PKC_PKCi_PRKCZ_ST	P28329	CHAT	Q05513	PRKCZ	S473	E476K	476	Missense	distal	3	no	23.005	32.448	EPSD	TCGA;COSMIC	31.494	Gain
AGC_PKC_PKCi_PRKCZ_ST	P28329	CHAT	Q05513	PRKCZ	S475	P478R	478	Missense	distal	3	no	15.928	31.995	EPSD	TCGA;COSMIC	31.494	Gain
AGC_PKC_PKCi_PRKCZ_ST	P28329	CHAT	Q05513	PRKCZ	S558	S556R	556	Missense	proximal	-2	no	30.107	42.198	EPSD	TCGA;COSMIC	31.494	Gain
AGC_PKC_PKCi_PRKCZ_ST	P46937	YAP1	Q05513	PRKCZ	S105	R106Q	106	Missense	proximal	1	no	34.124	31.851	EPSD	TCGA;ICGC;COSMIC;CCLE	31.494	Down-regulation
AGC_PKC_PKCi_PRKCZ_ST	P46937	YAP1	Q05513	PRKCZ	S105	S109N	109	Missense	distal	4	no	34.124	34.340	EPSD	TCGA;ICGC;COSMIC	31.494	Up-regulation
AGC_PKC_PKCi_PRKCZ_ST	P46937	YAP1	Q05513	PRKCZ	S109	R106Q	106	Missense	distal	-3	no	47.612	35.725	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC;CCLE	31.494	Down-regulation
AGC_PKC_PKCi_PRKCZ_ST	P46937	YAP1	Q05513	PRKCZ	S109	S109N	109	Missense	central	0	yes	47.612	0.000	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	31.494	Loss
AGC_PKC_PKCi_PRKCZ_ST	P46937	YAP1	Q05513	PRKCZ	S397	E396D	396	Missense	proximal	-1	no	36.276	36.917	EPSD	TCGA;ICGC;COSMIC	31.494	Up-regulation
AGC_PKC_PKCi_PRKCZ_ST	P46937	YAP1	Q05513	PRKCZ	S408	P413Q	413	Missense	distal	5	no	34.382	34.319	EPSD	TCGA;ICGC;COSMIC	31.494	Down-regulation
AGC_PKC_PKCi_PRKCZ_ST	P46937	YAP1	Q05513	PRKCZ	T428	E422D	422	Missense	distal	-6	no	34.511	34.303	EPSD	TCGA;COSMIC	31.494	Down-regulation
AGC_PKC_PKCi_PRKCZ_ST	P46937	YAP1	Q05513	PRKCZ	S499	L501F	501	Missense	proximal	2	no	38.495	34.884	EPSD	TCGA;ICGC;COSMIC	31.494	Down-regulation
AGC_PKC_PKCi_PRKCZ_ST	Q5JVS0	HABP4	Q05513	PRKCZ	T375	R369H	369	Missense	distal	-6	no	43.427	43.771	PhosphoSitePlus;EPSD	TCGA;COSMIC	31.494	Up-regulation
AGC_PKC_PKCi_PRKCZ_ST	Q5JVS0	HABP4	Q05513	PRKCZ	T375	G377E	377	Missense	proximal	2	no	43.427	40.436	PhosphoSitePlus;EPSD	TCGA;COSMIC;GDSC;CCLE	31.494	Down-regulation
AGC_PKC_PKCi_PRKCZ_ST	O14920	IKBKB	Q05513	PRKCZ	S177	G176D	176	Missense	proximal	-1	no	38.061	37.543	PhosphoSitePlus;EPSD	TCGA;COSMIC	31.494	Down-regulation
AGC_PKC_PKCi_PRKCZ_ST	O14920	IKBKB	Q05513	PRKCZ	S177	K171R	171	Missense	distal	-6	no	38.061	37.839	PhosphoSitePlus;EPSD	TCGA;COSMIC	31.494	Down-regulation
AGC_PKC_PKCi_PRKCZ_ST	O14920	IKBKB	Q05513	PRKCZ	S177	V183M	183	Missense	distal	6	no	38.061	38.802	PhosphoSitePlus;EPSD	TCGA;COSMIC	31.494	Up-regulation
AGC_PKC_PKCi_PRKCZ_ST	O14920	IKBKB	Q05513	PRKCZ	S239	H232R	232	Missense	distal	-7	no	30.559	33.910	EPSD	TCGA;COSMIC	31.494	Gain
AGC_PKC_PKCi_PRKCZ_ST	O14920	IKBKB	Q05513	PRKCZ	S239	Q237R	237	Missense	proximal	-2	no	30.559	40.546	EPSD	TCGA;COSMIC	31.494	Gain
AGC_PKC_PKCi_PRKCZ_ST	O14920	IKBKB	Q05513	PRKCZ	S335	L336F	336	Missense	proximal	1	no	39.648	40.591	EPSD	TCGA;COSMIC	31.494	Up-regulation
AGC_PKC_PKCi_PRKCZ_ST	O14920	IKBKB	Q05513	PRKCZ	S335	K337N	337	Missense	proximal	2	no	39.648	32.290	EPSD	TCGA;GDSC;CCLE	31.494	Down-regulation
AGC_PKC_PKCi_PRKCZ_ST	Q8IX03	WWC1	Q05513	PRKCZ	S533	P536S	536	Missense	distal	3	no	27.209	33.779	EPSD	TCGA;ICGC;COSMIC	31.494	Gain
AGC_PKC_PKCi_PRKCZ_ST	Q8IX03	WWC1	Q05513	PRKCZ	T923	R926C	926	Missense	distal	3	no	31.551	16.491	EPSD	TCGA;ICGC;COSMIC	31.494	Loss
AGC_PKC_PKCi_PRKCZ_ST	Q8IX03	WWC1	Q05513	PRKCZ	T923	R920L	920	Missense	distal	-3	no	31.551	19.234	EPSD	TCGA;ICGC;COSMIC	31.494	Loss
AGC_PKC_PKCi_PRKCZ_ST	Q8IX03	WWC1	Q05513	PRKCZ	T923	F930S	930	Missense	distal	7	no	31.551	30.255	EPSD	TCGA;ICGC;COSMIC	31.494	Loss
AGC_PKC_PKCi_PRKCZ_ST	Q8IX03	WWC1	Q05513	PRKCZ	S947	R941W	941	Missense	distal	-6	no	32.425	33.100	EPSD	TCGA;ICGC;COSMIC	31.494	Up-regulation
AGC_PKC_PKCi_PRKCZ_ST	Q8IX03	WWC1	Q05513	PRKCZ	S962	R960Q	960	Missense	proximal	-2	no	43.096	33.110	EPSD	TCGA;ICGC;COSMIC	31.494	Down-regulation
AGC_PKC_PKCi_PRKCZ_ST	Q8IX03	WWC1	Q05513	PRKCZ	S962	S967N	967	Missense	distal	5	no	43.096	43.456	EPSD	TCGA;ICGC;COSMIC	31.494	Up-regulation
AGC_PKC_PKCi_PRKCZ_ST	Q8IX03	WWC1	Q05513	PRKCZ	S962	V968I	968	Missense	distal	6	no	43.096	42.427	EPSD	TCGA;ICGC;COSMIC	31.494	Down-regulation
AGC_PKC_PKCi_PRKCZ_ST	Q8IX03	WWC1	Q05513	PRKCZ	S974	S967N	967	Missense	distal	-7	no	37.061	36.861	EPSD	TCGA;ICGC;COSMIC	31.494	Down-regulation
AGC_PKC_PKCi_PRKCZ_ST	Q8IX03	WWC1	Q05513	PRKCZ	S974	V968I	968	Missense	distal	-6	no	37.061	37.076	EPSD	TCGA;ICGC;COSMIC	31.494	Up-regulation
AGC_PKC_PKCi_PRKCZ_ST	Q8IX03	WWC1	Q05513	PRKCZ	S974	R972Q	972	Missense	proximal	-2	no	37.061	27.074	EPSD	TCGA;ICGC;COSMIC;GDSC	31.494	Loss
AGC_PKC_PKCi_PRKCZ_ST	Q8IX03	WWC1	Q05513	PRKCZ	S978	R972Q	972	Missense	distal	-6	no	37.486	37.885	PhosphoSitePlus;EPSD	TCGA;ICGC;COSMIC;GDSC	31.494	Up-regulation
AGC_PKC_PKCi_PRKCZ_ST	P55040	GEM	Q05513	PRKCZ	T7	G11S	11	Missense	distal	4	no	28.005	32.208	EPSD	TCGA;ICGC;COSMIC	31.494	Gain
AGC_PKC_PKCi_PRKCZ_ST	P55040	GEM	Q05513	PRKCZ	T12	G11S	11	Missense	proximal	-1	no	39.531	38.883	EPSD	TCGA;ICGC;COSMIC	31.494	Down-regulation
AGC_PKC_PKCi_PRKCZ_ST	P55040	GEM	Q05513	PRKCZ	T12	R9C	9	Missense	distal	-3	no	39.531	19.497	EPSD	TCGA;ICGC;COSMIC;CCLE	31.494	Loss
AGC_PKC_PKCi_PRKCZ_ST	P55040	GEM	Q05513	PRKCZ	T49	R45S	45	Missense	distal	-4	no	31.274	31.574	EPSD	TCGA;ICGC;COSMIC	31.494	Gain
AGC_PKC_PKCi_PRKCZ_ST	P55040	GEM	Q05513	PRKCZ	S59	S57R	57	Missense	proximal	-2	no	28.022	40.113	EPSD	TCGA;ICGC;COSMIC	31.494	Gain
AGC_PKC_PKCi_PRKCZ_ST	P55040	GEM	Q05513	PRKCZ	S261	S261R	261	Missense	central	0	yes	45.568	0.000	PhosphoSitePlus	TCGA;ICGC;COSMIC	31.494	Loss
AGC_PKC_PKCi_PRKCZ_ST	P55040	GEM	Q05513	PRKCZ	S261	Q256H	256	Missense	distal	-5	no	45.568	44.531	PhosphoSitePlus	TCGA;ICGC;COSMIC	31.494	Down-regulation
AGC_PKC_PKCi_PRKCZ_ST	P55040	GEM	Q05513	PRKCZ	S261	R268H	268	Missense	distal	7	no	45.568	45.027	PhosphoSitePlus	TCGA;ICGC;COSMIC;GDSC;CCLE	31.494	Down-regulation
AGC_PKC_PKCi_PRKCZ_ST	P55040	GEM	Q05513	PRKCZ	S287	S289F	289	Missense	proximal	2	no	32.483	31.432	EPSD	TCGA;ICGC;COSMIC	31.494	Loss
AGC_PKC_PKCi_PRKCZ_ST	P55040	GEM	Q05513	PRKCZ	S287	S294F	294	Missense	distal	7	no	32.483	33.779	EPSD	TCGA;ICGC;COSMIC	31.494	Up-regulation
AGC_PKC_PKCi_PRKCZ_ST	P55040	GEM	Q05513	PRKCZ	S289	S289F	289	Missense	central	0	yes	41.537	0.000	EPSD	TCGA;ICGC;COSMIC	31.494	Loss
AGC_PKC_PKCi_PRKCZ_ST	P55040	GEM	Q05513	PRKCZ	S289	S294F	294	Missense	distal	5	no	41.537	41.357	EPSD	TCGA;ICGC;COSMIC	31.494	Down-regulation
AGC_PKC_PKCi_PRKCZ_ST	Q12933	TRAF2	Q05513	PRKCZ	T117	W114R	114	Missense	distal	-3	no	20.637	44.393	EPSD	TCGA;ICGC;COSMIC	31.494	Gain
AGC_PKC_PKCi_PRKCZ_ST	Q12933	TRAF2	Q05513	PRKCZ	S162	R164W	164	Missense	proximal	2	no	37.114	22.777	EPSD	TCGA;ICGC;COSMIC	31.494	Loss
AGC_PKC_PKCi_PRKCZ_ST	Q12933	TRAF2	Q05513	PRKCZ	S162	R167W	167	Missense	distal	5	no	37.114	36.287	EPSD	TCGA;ICGC	31.494	Down-regulation
AGC_PKC_PKCi_PRKCZ_ST	Q12933	TRAF2	Q05513	PRKCZ	S274	A280V	280	Missense	distal	6	no	37.917	35.997	EPSD	TCGA;ICGC;COSMIC	31.494	Down-regulation
AGC_PKC_PKCi_PRKCZ_ST	P14598	NCF1	Q05513	PRKCZ	T45	E49K	49	Missense	distal	4	no	31.345	33.012	EPSD	TCGA;ICGC;COSMIC;GDSC	31.494	Gain
AGC_PKC_PKCi_PRKCZ_ST	P14598	NCF1	Q05513	PRKCZ	T93	E96K	96	Missense	distal	3	no	27.383	36.826	EPSD	TCGA;ICGC;COSMIC	31.494	Gain
AGC_PKC_PKCi_PRKCZ_ST	P14598	NCF1	Q05513	PRKCZ	S173	L177M	177	Missense	distal	4	no	26.762	34.559	EPSD	TCGA;ICGC	31.494	Gain
AGC_PKC_PKCi_PRKCZ_ST	P14598	NCF1	Q05513	PRKCZ	S288	V287M	287	Missense	proximal	-1	no	31.117	31.668	EPSD	TCGA;ICGC;COSMIC	31.494	Gain
AGC_PKC_PKCi_PRKCZ_ST	P14598	NCF1	Q05513	PRKCZ	S328	F331S	331	Missense	distal	3	no	37.308	44.362	EPSD	TCGA;ICGC;COSMIC	31.494	Up-regulation
AGC_PKC_PKCi_PRKCZ_ST	Q04206	RELA	Q05513	PRKCZ	S131	R133H	133	Missense	proximal	2	no	36.152	31.999	EPSD	TCGA;ICGC;COSMIC	31.494	Down-regulation
AGC_PKC_PKCi_PRKCZ_ST	Q04206	RELA	Q05513	PRKCZ	S131	E127K	127	Missense	distal	-4	no	36.152	35.823	EPSD	TCGA;ICGC;COSMIC	31.494	Down-regulation
AGC_PKC_PKCi_PRKCZ_ST	Q04206	RELA	Q05513	PRKCZ	S269	S276F	276	Missense	distal	7	no	36.479	37.775	EPSD	TCGA;ICGC;COSMIC	31.494	Up-regulation
AGC_PKC_PKCi_PRKCZ_ST	Q04206	RELA	Q05513	PRKCZ	S269	R274W	274	Missense	distal	5	no	36.479	35.652	EPSD	TCGA;ICGC	31.494	Down-regulation
AGC_PKC_PKCi_PRKCZ_ST	Q04206	RELA	Q05513	PRKCZ	S269	R273W	273	Missense	distal	4	no	36.479	22.608	EPSD	TCGA;ICGC	31.494	Loss
AGC_PKC_PKCi_PRKCZ_ST	Q04206	RELA	Q05513	PRKCZ	S276	S276F	276	Missense	central	0	yes	44.397	0.000	EPSD	TCGA;ICGC;COSMIC	31.494	Loss
AGC_PKC_PKCi_PRKCZ_ST	Q04206	RELA	Q05513	PRKCZ	S276	R274W	274	Missense	proximal	-2	no	44.397	26.224	EPSD	TCGA;ICGC	31.494	Loss
AGC_PKC_PKCi_PRKCZ_ST	Q04206	RELA	Q05513	PRKCZ	S276	R273W	273	Missense	distal	-3	no	44.397	20.641	EPSD	TCGA;ICGC	31.494	Loss
AGC_PKC_PKCi_PRKCZ_ST	Q04206	RELA	Q05513	PRKCZ	S311	F309L	309	Missense	proximal	-2	no	37.373	40.121	PhosphoSitePlus	TCGA;ICGC;COSMIC	31.494	Up-regulation
AGC_PKC_PKCi_PRKCZ_ST	Q04206	RELA	Q05513	PRKCZ	S311	E307K	307	Missense	distal	-4	no	37.373	37.044	PhosphoSitePlus	TCGA;ICGC;COSMIC	31.494	Down-regulation
AGC_PKC_PKCi_PRKCZ_ST	Q04206	RELA	Q05513	PRKCZ	S311	T308A	308	Missense	distal	-3	no	37.373	32.753	PhosphoSitePlus	TCGA;ICGC;COSMIC	31.494	Down-regulation
AGC_PKC_PKCi_PRKCZ_ST	Q04206	RELA	Q05513	PRKCZ	S468	V469I	469	Missense	proximal	1	no	33.736	33.261	EPSD	TCGA;ICGC;COSMIC	31.494	Down-regulation
AGC_PKC_PKCi_PRKCZ_ST	Q04206	RELA	Q05513	PRKCZ	T505	A507S	507	Missense	proximal	2	no	44.864	42.163	EPSD	TCGA	31.494	Down-regulation
AGC_PKC_PKCi_PRKCZ_ST	Q04206	RELA	Q05513	PRKCZ	T505	A507T	507	Missense	proximal	2	no	44.864	43.252	EPSD	TCGA;ICGC;COSMIC	31.494	Down-regulation
AGC_PKC_PKCi_PRKCZ_ST	Q04206	RELA	Q05513	PRKCZ	T505	E498D	498	Missense	distal	-7	no	44.864	48.587	EPSD	TCGA;ICGC;COSMIC	31.494	Up-regulation
AGC_PKC_PKCi_PRKCZ_ST	Q04206	RELA	Q05513	PRKCZ	T505	E498K	498	Missense	distal	-7	no	44.864	50.684	EPSD	TCGA;ICGC;COSMIC	31.494	Up-regulation
AGC_PKC_PKCi_PRKCZ_ST	Q04206	RELA	Q05513	PRKCZ	S536	S529L	529	Missense	distal	-7	no	42.930	43.322	EPSD	TCGA;ICGC;COSMIC;GDSC;CCLE	31.494	Up-regulation
AGC_PKC_PKCi_PRKCZ_ST	Q16236	NFE2L2	Q05513	PRKCZ	S40	Y46H	46	Missense	distal	6	no	30.141	37.749	PhosphoSitePlus	TCGA	31.494	Gain
AGC_PKC_PKCi_PRKCZ_ST	Q16236	NFE2L2	Q05513	PRKCZ	S447	A452T	452	Missense	distal	5	no	49.201	48.928	EPSD	TCGA;COSMIC	31.494	Down-regulation
AGC_PKC_PKCi_PRKCZ_ST	Q16236	NFE2L2	Q05513	PRKCZ	S447	S448I	448	Missense	proximal	1	no	49.201	50.191	EPSD	TCGA	31.494	Up-regulation
AGC_PKC_PKCi_PRKCZ_ST	Q16236	NFE2L2	Q05513	PRKCZ	S447	R449H	449	Missense	proximal	2	no	49.201	45.047	EPSD	TCGA;COSMIC;GDSC	31.494	Down-regulation
Other_PLK_PLK2_PLK3_ST	P15336	ATF2	Q9H4B4	PLK3	T69	P70S	70	Missense	proximal	1	no	16.687	16.083	PhosphoSitePlus;EPSD	TCGA;COSMIC	8.404	Down-regulation
Other_PLK_PLK2_PLK3_ST	P15336	ATF2	Q9H4B4	PLK3	T71	P70S	70	Missense	proximal	-1	no	15.978	15.751	EPSD;PhosphoSitePlus	TCGA;COSMIC	8.404	Down-regulation
Other_PLK_PLK2_PLK3_ST	P15336	ATF2	Q9H4B4	PLK3	S100	E93Q	93	Missense	distal	-7	no	8.696	9.224	EPSD	TCGA;COSMIC	8.404	Up-regulation
Other_PLK_PLK2_PLK3_ST	P15336	ATF2	Q9H4B4	PLK3	S112	T116A	116	Missense	distal	4	no	8.645	9.458	EPSD	TCGA;COSMIC	8.404	Up-regulation
Other_PLK_PLK2_PLK3_ST	P15336	ATF2	Q9H4B4	PLK3	S112	S112P	112	Missense	central	0	yes	8.645	0.000	EPSD	TCGA;COSMIC	8.404	Loss
Other_PLK_PLK2_PLK3_ST	P15336	ATF2	Q9H4B4	PLK3	T145	E148K	148	Missense	distal	3	no	9.265	8.152	EPSD	TCGA;COSMIC	8.404	Loss
Other_PLK_PLK2_PLK3_ST	P15336	ATF2	Q9H4B4	PLK3	S310	P312L	312	Missense	proximal	2	no	9.437	9.460	EPSD	TCGA;COSMIC	8.404	Up-regulation
Other_PLK_PLK2_PLK3_ST	P15336	ATF2	Q9H4B4	PLK3	S310	E308Q	308	Missense	proximal	-2	no	9.437	4.680	EPSD	TCGA;COSMIC	8.404	Loss
Other_PLK_PLK2_PLK3_ST	P15336	ATF2	Q9H4B4	PLK3	S310	R304S	304	Missense	distal	-6	no	9.437	11.527	EPSD	TCGA;COSMIC	8.404	Up-regulation
Other_PLK_PLK2_PLK3_ST	P15336	ATF2	Q9H4B4	PLK3	S310	S310F	310	Missense	central	0	yes	9.437	0.000	EPSD	TCGA;COSMIC	8.404	Loss
Other_PLK_PLK2_PLK3_ST	P15336	ATF2	Q9H4B4	PLK3	T322	S321F	321	Missense	proximal	-1	no	8.380	9.001	EPSD	TCGA;COSMIC	8.404	Gain
Other_PLK_PLK2_PLK3_ST	P15336	ATF2	Q9H4B4	PLK3	T336	P334A	334	Missense	proximal	-2	no	8.857	9.481	EPSD	TCGA;COSMIC	8.404	Up-regulation
Other_PLK_PLK2_PLK3_ST	P15336	ATF2	Q9H4B4	PLK3	T336	T339A	339	Missense	distal	3	no	8.857	8.741	EPSD	TCGA;COSMIC	8.404	Down-regulation
Other_PLK_PLK2_PLK3_ST	P15336	ATF2	Q9H4B4	PLK3	S442	D436N	436	Missense	distal	-6	no	9.235	8.851	EPSD	TCGA;COSMIC	8.404	Down-regulation
Other_PLK_PLK2_PLK3_ST	P15336	ATF2	Q9H4B4	PLK3	S442	S438L	438	Missense	distal	-4	no	9.235	10.646	EPSD	TCGA;COSMIC	8.404	Up-regulation
Other_PLK_PLK2_PLK3_ST	P15336	ATF2	Q9H4B4	PLK3	S458	S456L	456	Missense	proximal	-2	no	8.099	9.178	EPSD	TCGA;COSMIC	8.404	Gain
Other_PLK_PLK2_PLK3_ST	P15336	ATF2	Q9H4B4	PLK3	S458	Q453H	453	Missense	distal	-5	no	8.099	8.698	EPSD	TCGA;COSMIC	8.404	Gain
Other_PLK_PLK2_PLK3_ST	P62258	YWHAE	Q9H4B4	PLK3	T38	R42I	42	Missense	distal	4	no	10.359	11.059	EPSD	TCGA;ICGC;COSMIC	8.404	Up-regulation
Other_PLK_PLK2_PLK3_ST	P62258	YWHAE	Q9H4B4	PLK3	S46	R42I	42	Missense	distal	-4	no	11.599	11.890	EPSD	TCGA;ICGC;COSMIC	8.404	Up-regulation
Other_PLK_PLK2_PLK3_ST	P62258	YWHAE	Q9H4B4	PLK3	T208	T208K	208	Missense	central	0	yes	16.671	0.000	PhosphoSitePlus	TCGA	8.404	Loss
Other_PLK_PLK2_PLK3_ST	P62258	YWHAE	Q9H4B4	PLK3	S210	T208K	208	Missense	proximal	-2	no	11.170	9.335	EPSD	TCGA	8.404	Down-regulation
Other_PLK_PLK2_PLK3_ST	P62258	YWHAE	Q9H4B4	PLK3	S213	T208K	208	Missense	distal	-5	no	8.508	8.420	EPSD	TCGA	8.404	Down-regulation
Other_PLK_PLK2_PLK3_ST	O96017	CHEK2	Q9H4B4	PLK3	S62	S56R	56	Missense	distal	-6	no	16.118	14.028	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	8.404	Down-regulation
Other_PLK_PLK2_PLK3_ST	O96017	CHEK2	Q9H4B4	PLK3	T65	E70G	70	Missense	distal	5	no	8.947	9.874	EPSD	TCGA	8.404	Up-regulation
Other_PLK_PLK2_PLK3_ST	O96017	CHEK2	Q9H4B4	PLK3	S73	D77H	77	Missense	distal	4	no	16.249	17.228	PhosphoSitePlus;EPSD	TCGA;ICGC;COSMIC	8.404	Up-regulation
Other_PLK_PLK2_PLK3_ST	O96017	CHEK2	Q9H4B4	PLK3	S73	E70G	70	Missense	distal	-3	no	16.249	12.253	PhosphoSitePlus;EPSD	TCGA	8.404	Down-regulation
Other_PLK_PLK2_PLK3_ST	O96017	CHEK2	Q9H4B4	PLK3	S357	E351Q	351	Missense	distal	-6	no	9.449	6.736	EPSD	TCGA;COSMIC	8.404	Loss
Other_PLK_PLK2_PLK3_ST	P11388	TOP2A	Q9H4B4	PLK3	S387	S387R	387	Missense	central	0	yes	8.839	0.000	EPSD	TCGA	8.404	Loss
Other_PLK_PLK2_PLK3_ST	P11388	TOP2A	Q9H4B4	PLK3	S812	S812F	812	Missense	central	0	yes	9.560	0.000	EPSD	TCGA;ICGC;COSMIC	8.404	Loss
Other_PLK_PLK2_PLK3_ST	P11388	TOP2A	Q9H4B4	PLK3	T950	N945I	945	Missense	distal	-5	no	9.241	10.581	EPSD	TCGA	8.404	Up-regulation
Other_PLK_PLK2_PLK3_ST	P11388	TOP2A	Q9H4B4	PLK3	T950	T955A	955	Missense	distal	5	no	9.241	9.610	EPSD	TCGA;ICGC;COSMIC	8.404	Up-regulation
Other_PLK_PLK2_PLK3_ST	P11388	TOP2A	Q9H4B4	PLK3	T950	E948G	948	Missense	proximal	-2	no	9.241	4.101	EPSD	TCGA;ICGC;COSMIC	8.404	Loss
Other_PLK_PLK2_PLK3_ST	P11388	TOP2A	Q9H4B4	PLK3	T950	E948D	948	Missense	proximal	-2	no	9.241	6.176	EPSD	TCGA;ICGC	8.404	Loss
Other_PLK_PLK2_PLK3_ST	P11388	TOP2A	Q9H4B4	PLK3	S1115	S1117C	1117	Missense	proximal	2	no	10.674	10.228	EPSD	TCGA;ICGC;COSMIC	8.404	Down-regulation
Other_PLK_PLK2_PLK3_ST	P11388	TOP2A	Q9H4B4	PLK3	S1115	D1116N	1116	Missense	proximal	1	no	10.674	9.464	EPSD	TCGA;ICGC;COSMIC	8.404	Down-regulation
Other_PLK_PLK2_PLK3_ST	P11388	TOP2A	Q9H4B4	PLK3	S1115	S1117F	1117	Missense	proximal	2	no	10.674	10.543	EPSD	TCGA;ICGC;COSMIC	8.404	Down-regulation
Other_PLK_PLK2_PLK3_ST	P11388	TOP2A	Q9H4B4	PLK3	S1115	D1120Y	1120	Missense	distal	5	no	10.674	10.421	EPSD	TCGA;ICGC	8.404	Down-regulation
Other_PLK_PLK2_PLK3_ST	P11388	TOP2A	Q9H4B4	PLK3	T1119	S1117C	1117	Missense	proximal	-2	no	11.164	8.966	EPSD	TCGA;ICGC;COSMIC	8.404	Down-regulation
Other_PLK_PLK2_PLK3_ST	P11388	TOP2A	Q9H4B4	PLK3	T1119	D1116N	1116	Missense	distal	-3	no	11.164	7.442	EPSD	TCGA;ICGC;COSMIC	8.404	Loss
Other_PLK_PLK2_PLK3_ST	P11388	TOP2A	Q9H4B4	PLK3	T1119	S1117F	1117	Missense	proximal	-2	no	11.164	10.704	EPSD	TCGA;ICGC;COSMIC	8.404	Down-regulation
Other_PLK_PLK2_PLK3_ST	P11388	TOP2A	Q9H4B4	PLK3	T1119	D1120Y	1120	Missense	proximal	1	no	11.164	11.109	EPSD	TCGA;ICGC	8.404	Down-regulation
Other_PLK_PLK2_PLK3_ST	P11388	TOP2A	Q9H4B4	PLK3	S1121	S1117C	1117	Missense	distal	-4	no	11.717	12.223	EPSD	TCGA;ICGC;COSMIC	8.404	Up-regulation
Other_PLK_PLK2_PLK3_ST	P11388	TOP2A	Q9H4B4	PLK3	S1121	D1116N	1116	Missense	distal	-5	no	11.717	12.489	EPSD	TCGA;ICGC;COSMIC	8.404	Up-regulation
Other_PLK_PLK2_PLK3_ST	P11388	TOP2A	Q9H4B4	PLK3	S1121	S1117F	1117	Missense	distal	-4	no	11.717	13.979	EPSD	TCGA;ICGC;COSMIC	8.404	Up-regulation
Other_PLK_PLK2_PLK3_ST	P11388	TOP2A	Q9H4B4	PLK3	S1121	D1120Y	1120	Missense	proximal	-1	no	11.717	11.301	EPSD	TCGA;ICGC	8.404	Down-regulation
Other_PLK_PLK2_PLK3_ST	P11388	TOP2A	Q9H4B4	PLK3	T1343	P1350L	1350	Missense	distal	7	no	22.301	22.047	PhosphoSitePlus	TCGA	8.404	Down-regulation
Other_PLK_PLK2_PLK3_ST	P11388	TOP2A	Q9H4B4	PLK3	T1343	F1336L	1336	Missense	distal	-7	no	22.301	22.154	PhosphoSitePlus	TCGA;ICGC;COSMIC	8.404	Down-regulation
Other_PLK_PLK2_PLK3_ST	P11388	TOP2A	Q9H4B4	PLK3	S1377	E1380K	1380	Missense	distal	3	no	10.867	9.754	EPSD	TCGA;ICGC;COSMIC;GDSC;CCLE	8.404	Down-regulation
Other_PLK_PLK2_PLK3_ST	P11388	TOP2A	Q9H4B4	PLK3	S1377	D1382H	1382	Missense	distal	5	no	10.867	11.306	EPSD	TCGA;ICGC;COSMIC	8.404	Up-regulation
Other_PLK_PLK2_PLK3_ST	P11388	TOP2A	Q9H4B4	PLK3	S1387	D1382H	1382	Missense	distal	-5	no	7.176	8.976	EPSD	TCGA;ICGC;COSMIC	8.404	Gain
Other_PLK_PLK2_PLK3_ST	P60484	PTEN	Q9H4B4	PLK3	S294	L295V	295	Missense	proximal	1	no	11.776	10.958	EPSD	TCGA;ICGC;COSMIC	8.404	Down-regulation
Other_PLK_PLK2_PLK3_ST	P60484	PTEN	Q9H4B4	PLK3	S294	D297N	297	Missense	distal	3	no	11.776	10.437	EPSD	TCGA	8.404	Down-regulation
Other_PLK_PLK2_PLK3_ST	P60484	PTEN	Q9H4B4	PLK3	T321	L325F	325	Missense	distal	4	no	8.272	9.021	EPSD	TCGA;ICGC;COSMIC	8.404	Gain
Other_PLK_PLK2_PLK3_ST	P60484	PTEN	Q9H4B4	PLK3	T321	D326H	326	Missense	distal	5	no	8.272	8.710	EPSD	TCGA;ICGC;COSMIC	8.404	Gain
Other_PLK_PLK2_PLK3_ST	P60484	PTEN	Q9H4B4	PLK3	T350	F347L	347	Missense	distal	-3	no	8.035	8.843	EPSD	TCGA;ICGC;COSMIC	8.404	Gain
Other_PLK_PLK2_PLK3_ST	P60484	PTEN	Q9H4B4	PLK3	T350	Y346D	346	Missense	distal	-4	no	8.035	8.757	EPSD	TCGA;ICGC;COSMIC	8.404	Gain
Other_PLK_PLK2_PLK3_ST	P60484	PTEN	Q9H4B4	PLK3	T350	Y346H	346	Missense	distal	-4	no	8.035	9.109	EPSD	TCGA;ICGC;COSMIC	8.404	Gain
Other_PLK_PLK2_PLK3_ST	P60484	PTEN	Q9H4B4	PLK3	T366	E373K	373	Missense	distal	7	no	17.213	16.710	PhosphoSitePlus;EPSD	TCGA;ICGC	8.404	Down-regulation
Other_PLK_PLK2_PLK3_ST	P60484	PTEN	Q9H4B4	PLK3	T366	N372D	372	Missense	distal	6	no	17.213	17.861	PhosphoSitePlus;EPSD	TCGA;ICGC;COSMIC	8.404	Up-regulation
Other_PLK_PLK2_PLK3_ST	P60484	PTEN	Q9H4B4	PLK3	S370	E373K	373	Missense	distal	3	no	17.644	16.531	EPSD;PhosphoSitePlus	TCGA;ICGC	8.404	Down-regulation
Other_PLK_PLK2_PLK3_ST	P60484	PTEN	Q9H4B4	PLK3	S370	N372D	372	Missense	proximal	2	no	17.644	19.071	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	8.404	Up-regulation
Other_PLK_PLK2_PLK3_ST	P08238	HSP90AB1	Q9H4B4	PLK3	S34	F32L	32	Missense	proximal	-2	no	7.242	8.781	EPSD	TCGA;ICGC;COSMIC;GDSC	8.404	Gain
Other_PLK_PLK2_PLK3_ST	P08238	HSP90AB1	Q9H4B4	PLK3	S45	I44M	44	Missense	proximal	-1	no	9.492	8.418	EPSD	TCGA;ICGC;COSMIC	8.404	Down-regulation
Other_PLK_PLK2_PLK3_ST	P08238	HSP90AB1	Q9H4B4	PLK3	S45	N46T	46	Missense	proximal	1	no	9.492	9.591	EPSD	TCGA;ICGC;COSMIC	8.404	Up-regulation
Other_PLK_PLK2_PLK3_ST	P08238	HSP90AB1	Q9H4B4	PLK3	S45	I38F	38	Missense	distal	-7	no	9.492	9.655	EPSD	TCGA;ICGC;COSMIC	8.404	Up-regulation
Other_PLK_PLK2_PLK3_ST	P08238	HSP90AB1	Q9H4B4	PLK3	S45	D52N	52	Missense	distal	7	no	9.492	9.082	EPSD	TCGA;ICGC;COSMIC	8.404	Down-regulation
Other_PLK_PLK2_PLK3_ST	P08238	HSP90AB1	Q9H4B4	PLK3	S58	D52N	52	Missense	distal	-6	no	11.600	11.217	EPSD	TCGA;ICGC;COSMIC	8.404	Down-regulation
Other_PLK_PLK2_PLK3_ST	P08238	HSP90AB1	Q9H4B4	PLK3	S58	Y56C	56	Missense	proximal	-2	no	11.600	11.684	EPSD	TCGA;ICGC;COSMIC	8.404	Up-regulation
Other_PLK_PLK2_PLK3_ST	P08238	HSP90AB1	Q9H4B4	PLK3	S63	Y56C	56	Missense	distal	-7	no	9.180	9.590	EPSD	TCGA;ICGC;COSMIC	8.404	Up-regulation
Other_PLK_PLK2_PLK3_ST	P08238	HSP90AB1	Q9H4B4	PLK3	S63	S67I	67	Missense	distal	4	no	9.180	9.598	EPSD	TCGA;ICGC	8.404	Up-regulation
Other_PLK_PLK2_PLK3_ST	P08238	HSP90AB1	Q9H4B4	PLK3	S160	S164A	164	Missense	distal	4	no	10.711	11.092	EPSD	TCGA;ICGC;COSMIC	8.404	Up-regulation
Other_PLK_PLK2_PLK3_ST	P08238	HSP90AB1	Q9H4B4	PLK3	S164	H171Y	171	Missense	distal	7	no	8.346	9.892	EPSD	TCGA;ICGC;COSMIC	8.404	Gain
Other_PLK_PLK2_PLK3_ST	P08238	HSP90AB1	Q9H4B4	PLK3	T297	E303K	303	Missense	distal	6	no	11.067	12.196	EPSD	TCGA;ICGC;COSMIC	8.404	Up-regulation
Other_PLK_PLK2_PLK3_ST	P08238	HSP90AB1	Q9H4B4	PLK3	T297	F304L	304	Missense	distal	7	no	11.067	12.068	EPSD	TCGA;ICGC;COSMIC	8.404	Up-regulation
Other_PLK_PLK2_PLK3_ST	P08238	HSP90AB1	Q9H4B4	PLK3	S434	K427N	427	Missense	distal	-7	no	12.129	11.892	EPSD	TCGA;ICGC;COSMIC	8.404	Down-regulation
Other_PLK_PLK2_PLK3_ST	P08238	HSP90AB1	Q9H4B4	PLK3	T446	R449H	449	Missense	distal	3	no	8.306	8.674	EPSD	TCGA;ICGC;COSMIC	8.404	Gain
Other_PLK_PLK2_PLK3_ST	P08238	HSP90AB1	Q9H4B4	PLK3	T446	R448H	448	Missense	proximal	2	no	8.306	9.857	EPSD	TCGA;ICGC;COSMIC	8.404	Gain
Other_PLK_PLK2_PLK3_ST	P08238	HSP90AB1	Q9H4B4	PLK3	T446	R448C	448	Missense	proximal	2	no	8.306	9.064	EPSD	TCGA;ICGC;COSMIC	8.404	Gain
Other_PLK_PLK2_PLK3_ST	P08238	HSP90AB1	Q9H4B4	PLK3	T537	S535L	535	Missense	proximal	-2	no	10.727	11.807	EPSD	TCGA;ICGC;COSMIC	8.404	Up-regulation
Other_PLK_PLK2_PLK3_ST	P08238	HSP90AB1	Q9H4B4	PLK3	S556	K552M	552	Missense	distal	-4	no	8.238	8.696	EPSD	TCGA;ICGC;COSMIC	8.404	Gain
Other_PLK_PLK2_PLK3_ST	P08238	HSP90AB1	Q9H4B4	PLK3	S556	K550E	550	Missense	distal	-6	no	8.238	10.644	EPSD	TCGA;ICGC;COSMIC	8.404	Gain
Other_PLK_PLK2_PLK3_ST	P08238	HSP90AB1	Q9H4B4	PLK3	T579	S586P	586	Missense	distal	7	no	10.122	10.027	EPSD	TCGA;ICGC;COSMIC	8.404	Down-regulation
Other_PLK_PLK2_PLK3_ST	P08238	HSP90AB1	Q9H4B4	PLK3	T579	K573T	573	Missense	distal	-6	no	10.122	11.573	EPSD	TCGA;ICGC	8.404	Up-regulation
Other_PLK_PLK2_PLK3_ST	P08238	HSP90AB1	Q9H4B4	PLK3	T616	R612Q	612	Missense	distal	-4	no	9.868	9.639	EPSD	TCGA;ICGC;COSMIC	8.404	Down-regulation
Other_PLK_PLK2_PLK3_ST	P08238	HSP90AB1	Q9H4B4	PLK3	S718	S718F	718	Missense	central	0	yes	9.874	0.000	PhosphoSitePlus	TCGA;ICGC;COSMIC	8.404	Loss
Other_PLK_PLK2_PLK3_ST	P08238	HSP90AB1	Q9H4B4	PLK3	S718	D714N	714	Missense	distal	-4	no	9.874	7.641	PhosphoSitePlus	TCGA;ICGC;COSMIC	8.404	Loss
Other_PLK_PLK2_PLK3_ST	P08238	HSP90AB1	Q9H4B4	PLK3	S718	V723A	723	Missense	distal	5	no	9.874	10.068	PhosphoSitePlus	TCGA;ICGC	8.404	Up-regulation
Other_PLK_PLK2_PLK3_ST	P06748	NPM1	Q9H4B4	PLK3	S4	D3Y	3	Missense	proximal	-1	no	15.746	15.330	PhosphoSitePlus	TCGA	8.404	Down-regulation
Other_PLK_PLK2_PLK3_ST	P06748	NPM1	Q9H4B4	PLK3	S4	S4L	4	Missense	central	0	yes	15.746	0.000	PhosphoSitePlus	TCGA;ICGC;COSMIC	8.404	Loss
Other_PLK_PLK2_PLK3_ST	P06748	NPM1	Q9H4B4	PLK3	S10	D3Y	3	Missense	distal	-7	no	8.628	8.314	EPSD	TCGA	8.404	Loss
Other_PLK_PLK2_PLK3_ST	P06748	NPM1	Q9H4B4	PLK3	S10	L12M	12	Missense	proximal	2	no	8.628	10.447	EPSD	TCGA;ICGC;COSMIC	8.404	Up-regulation
Other_PLK_PLK2_PLK3_ST	P06748	NPM1	Q9H4B4	PLK3	S10	S4L	4	Missense	distal	-6	no	8.628	5.804	EPSD	TCGA;ICGC;COSMIC	8.404	Loss
Other_PLK_PLK2_PLK3_ST	P06748	NPM1	Q9H4B4	PLK3	T46	V47F	47	Missense	proximal	1	no	7.310	8.687	EPSD	TCGA;ICGC;COSMIC	8.404	Gain
Other_PLK_PLK2_PLK3_ST	P06748	NPM1	Q9H4B4	PLK3	S139	L136F	136	Missense	distal	-3	no	10.224	9.416	EPSD	TCGA;ICGC;COSMIC	8.404	Down-regulation
Other_PLK_PLK2_PLK3_ST	P06748	NPM1	Q9H4B4	PLK3	S139	I138V	138	Missense	proximal	-1	no	10.224	8.865	EPSD	TCGA;ICGC;COSMIC;GDSC;CCLE	8.404	Down-regulation
Other_PLK_PLK2_PLK3_ST	P06748	NPM1	Q9H4B4	PLK3	S143	L136F	136	Missense	distal	-7	no	9.238	9.385	EPSD	TCGA;ICGC;COSMIC	8.404	Up-regulation
Other_PLK_PLK2_PLK3_ST	P06748	NPM1	Q9H4B4	PLK3	S143	I138V	138	Missense	distal	-5	no	9.238	7.864	EPSD	TCGA;ICGC;COSMIC;GDSC;CCLE	8.404	Loss
Other_PLK_PLK2_PLK3_ST	P06748	NPM1	Q9H4B4	PLK3	S143	G147D	147	Missense	distal	4	no	9.238	8.860	EPSD	TCGA;ICGC;COSMIC	8.404	Down-regulation
Other_PLK_PLK2_PLK3_ST	P06748	NPM1	Q9H4B4	PLK3	S149	G147D	147	Missense	proximal	-2	no	6.700	8.774	EPSD	TCGA;ICGC;COSMIC	8.404	Gain
Other_PLK_PLK2_PLK3_ST	P06748	NPM1	Q9H4B4	PLK3	S222	P216S	216	Missense	distal	-6	no	9.608	10.421	EPSD	TCGA;ICGC;COSMIC	8.404	Up-regulation
Other_PLK_PLK2_PLK3_ST	P06748	NPM1	Q9H4B4	PLK3	S243	K239N	239	Missense	distal	-4	no	10.094	8.663	EPSD	TCGA;ICGC;COSMIC	8.404	Down-regulation
Other_PLK_PLK2_PLK3_ST	P06748	NPM1	Q9H4B4	PLK3	S254	K257E	257	Missense	distal	3	no	11.211	12.324	EPSD	TCGA;ICGC;COSMIC	8.404	Up-regulation
Other_PLK_PLK2_PLK3_ST	P30307	CDC25C	Q9H4B4	PLK3	S14	S7L	7	Missense	distal	-7	no	10.589	10.184	EPSD	TCGA;ICGC;COSMIC	8.404	Down-regulation
Other_PLK_PLK2_PLK3_ST	P30307	CDC25C	Q9H4B4	PLK3	T40	D36Y	36	Missense	distal	-4	no	9.545	8.823	EPSD	TCGA;ICGC	8.404	Down-regulation
Other_PLK_PLK2_PLK3_ST	P30307	CDC25C	Q9H4B4	PLK3	S191	E188D	188	Missense	distal	-3	no	18.165	16.750	EPSD;PhosphoSitePlus	TCGA;ICGC	8.404	Down-regulation
Other_PLK_PLK2_PLK3_ST	P30307	CDC25C	Q9H4B4	PLK3	S191	E196K	196	Missense	distal	5	no	18.165	18.784	EPSD;PhosphoSitePlus	TCGA;ICGC	8.404	Up-regulation
Other_PLK_PLK2_PLK3_ST	P30307	CDC25C	Q9H4B4	PLK3	S198	Q202E	202	Missense	distal	4	no	14.670	13.912	PhosphoSitePlus;EPSD	TCGA;ICGC;COSMIC	8.404	Down-regulation
Other_PLK_PLK2_PLK3_ST	P30307	CDC25C	Q9H4B4	PLK3	S198	E196K	196	Missense	proximal	-2	no	14.670	9.774	PhosphoSitePlus;EPSD	TCGA;ICGC	8.404	Down-regulation
Other_PLK_PLK2_PLK3_ST	P30307	CDC25C	Q9H4B4	PLK3	S277	G280E	280	Missense	distal	3	no	9.436	11.068	EPSD	TCGA;ICGC;COSMIC	8.404	Up-regulation
Other_PLK_PLK2_PLK3_ST	P30307	CDC25C	Q9H4B4	PLK3	S277	S277C	277	Missense	central	0	yes	9.436	0.000	EPSD	TCGA;ICGC;COSMIC	8.404	Loss
Other_PLK_PLK2_PLK3_ST	P30307	CDC25C	Q9H4B4	PLK3	S277	N278K	278	Missense	proximal	1	no	9.436	10.404	EPSD	TCGA;ICGC;COSMIC	8.404	Up-regulation
Other_PLK_PLK2_PLK3_ST	P05412	JUN	Q9H4B4	PLK3	T8	F9L	9	Missense	proximal	1	no	9.222	8.663	EPSD	TCGA;ICGC;COSMIC	8.404	Down-regulation
Other_PLK_PLK2_PLK3_ST	P05412	JUN	Q9H4B4	PLK3	T8	A13D	13	Missense	distal	5	no	9.222	9.660	EPSD	TCGA;ICGC;COSMIC	8.404	Up-regulation
Other_PLK_PLK2_PLK3_ST	P05412	JUN	Q9H4B4	PLK3	T8	N15I	15	Missense	distal	7	no	9.222	8.416	EPSD	TCGA;ICGC;COSMIC	8.404	Down-regulation
Other_PLK_PLK2_PLK3_ST	P05412	JUN	Q9H4B4	PLK3	T8	E6K	6	Missense	proximal	-2	no	9.222	4.326	EPSD	TCGA;ICGC	8.404	Loss
Other_PLK_PLK2_PLK3_ST	P05412	JUN	Q9H4B4	PLK3	S37	S37I	37	Missense	central	0	yes	10.283	0.000	EPSD	TCGA;ICGC;COSMIC	8.404	Loss
Other_PLK_PLK2_PLK3_ST	P05412	JUN	Q9H4B4	PLK3	S37	L40M	40	Missense	distal	3	no	10.283	10.375	EPSD	TCGA;ICGC;COSMIC	8.404	Up-regulation
Other_PLK_PLK2_PLK3_ST	P05412	JUN	Q9H4B4	PLK3	S73	S73L	73	Missense	central	0	yes	16.576	0.000	PhosphoSitePlus;EPSD	TCGA;ICGC;COSMIC	8.404	Loss
Other_PLK_PLK2_PLK3_ST	P04637	TP53	Q9H4B4	PLK3	S9	P4L	4	Missense	distal	-5	no	9.149	8.101	EPSD	TCGA;ICGC;COSMIC	8.404	Loss
Other_PLK_PLK2_PLK3_ST	P04637	TP53	Q9H4B4	PLK3	S20	P27S	27	Missense	distal	7	no	14.863	14.958	PhosphoSitePlus	TCGA;ICGC;COSMIC	8.404	Up-regulation
Other_PLK_PLK2_PLK3_ST	P04637	TP53	Q9H4B4	PLK3	S20	P27L	27	Missense	distal	7	no	14.863	14.609	PhosphoSitePlus	TCGA;ICGC;COSMIC;GDSC;CCLE	8.404	Down-regulation
Other_PLK_PLK2_PLK3_ST	P04637	TP53	Q9H4B4	PLK3	S46	D48N	48	Missense	proximal	2	no	10.086	8.659	EPSD	TCGA;ICGC;COSMIC;GDSC;CCLE	8.404	Down-regulation
Other_PLK_PLK2_PLK3_ST	P04637	TP53	Q9H4B4	PLK3	T150	W146S	146	Missense	distal	-4	no	9.520	7.543	EPSD	TCGA;ICGC;COSMIC	8.404	Loss
Other_PLK_PLK2_PLK3_ST	P04637	TP53	Q9H4B4	PLK3	T150	P152L	152	Missense	proximal	2	no	9.520	9.543	EPSD	TCGA;ICGC;COSMIC;GDSC;CCLE	8.404	Up-regulation
Other_PLK_PLK2_PLK3_ST	P04637	TP53	Q9H4B4	PLK3	T150	D148N	148	Missense	proximal	-2	no	9.520	6.678	EPSD	TCGA;ICGC;COSMIC	8.404	Loss
Other_PLK_PLK2_PLK3_ST	P04637	TP53	Q9H4B4	PLK3	T150	P151H	151	Missense	proximal	1	no	9.520	9.406	EPSD	TCGA;ICGC;COSMIC;GDSC;CCLE	8.404	Down-regulation
Other_PLK_PLK2_PLK3_ST	P04637	TP53	Q9H4B4	PLK3	T150	P151A	151	Missense	proximal	1	no	9.520	9.397	EPSD	TCGA;ICGC;COSMIC;CCLE	8.404	Down-regulation
Other_PLK_PLK2_PLK3_ST	P04637	TP53	Q9H4B4	PLK3	T150	R156P	156	Missense	distal	6	no	9.520	10.066	EPSD	TCGA;ICGC;COSMIC;GDSC;CCLE	8.404	Up-regulation
Other_PLK_PLK2_PLK3_ST	P04637	TP53	Q9H4B4	PLK3	T150	V143A	143	Missense	distal	-7	no	9.520	9.162	EPSD	TCGA;ICGC;COSMIC;GDSC;CCLE	8.404	Down-regulation
Other_PLK_PLK2_PLK3_ST	P04637	TP53	Q9H4B4	PLK3	T150	P151S	151	Missense	proximal	1	no	9.520	8.915	EPSD	TCGA;ICGC;COSMIC;GDSC;CCLE	8.404	Down-regulation
Other_PLK_PLK2_PLK3_ST	P04637	TP53	Q9H4B4	PLK3	T150	V157F	157	Missense	distal	7	no	9.520	8.654	EPSD	TCGA;ICGC;COSMIC;GDSC;CCLE	8.404	Down-regulation
Other_PLK_PLK2_PLK3_ST	P04637	TP53	Q9H4B4	PLK3	T150	V157G	157	Missense	distal	7	no	9.520	8.987	EPSD	TCGA;ICGC;COSMIC	8.404	Down-regulation
Other_PLK_PLK2_PLK3_ST	P04637	TP53	Q9H4B4	PLK3	T150	V157D	157	Missense	distal	7	no	9.520	9.819	EPSD	TCGA;ICGC;COSMIC	8.404	Up-regulation
Other_PLK_PLK2_PLK3_ST	P04637	TP53	Q9H4B4	PLK3	T150	L145R	145	Missense	distal	-5	no	9.520	9.485	EPSD	TCGA;ICGC;COSMIC;GDSC;CCLE	8.404	Down-regulation
Other_PLK_PLK2_PLK3_ST	P04637	TP53	Q9H4B4	PLK3	T150	T155I	155	Missense	distal	5	no	9.520	10.051	EPSD	TCGA;ICGC;COSMIC;CCLE	8.404	Up-regulation
Other_PLK_PLK2_PLK3_ST	P04637	TP53	Q9H4B4	PLK3	T150	V143M	143	Missense	distal	-7	no	9.520	9.228	EPSD	TCGA;ICGC;COSMIC;GDSC;CCLE	8.404	Down-regulation
Other_PLK_PLK2_PLK3_ST	P04637	TP53	Q9H4B4	PLK3	T150	P152S	152	Missense	proximal	2	no	9.520	10.406	EPSD	TCGA;ICGC;COSMIC;CCLE	8.404	Up-regulation
Other_PLK_PLK2_PLK3_ST	P04637	TP53	Q9H4B4	PLK3	T150	R156C	156	Missense	distal	6	no	9.520	10.070	EPSD	TCGA;ICGC;COSMIC	8.404	Up-regulation
Other_PLK_PLK2_PLK3_ST	P04637	TP53	Q9H4B4	PLK3	T150	P151T	151	Missense	proximal	1	no	9.520	8.198	EPSD	TCGA;ICGC;COSMIC	8.404	Loss
Other_PLK_PLK2_PLK3_ST	P04637	TP53	Q9H4B4	PLK3	T150	T155P	155	Missense	distal	5	no	9.520	10.345	EPSD	TCGA;ICGC;COSMIC;CCLE	8.404	Up-regulation
Other_PLK_PLK2_PLK3_ST	P04637	TP53	Q9H4B4	PLK3	T150	V143G	143	Missense	distal	-7	no	9.520	9.944	EPSD	TCGA;ICGC;COSMIC	8.404	Up-regulation
Other_PLK_PLK2_PLK3_ST	P04637	TP53	Q9H4B4	PLK3	T150	P152Q	152	Missense	proximal	2	no	9.520	9.810	EPSD	TCGA;ICGC;COSMIC	8.404	Up-regulation
Other_PLK_PLK2_PLK3_ST	P04637	TP53	Q9H4B4	PLK3	T150	R156H	156	Missense	distal	6	no	9.520	10.096	EPSD	TCGA;ICGC;COSMIC	8.404	Up-regulation
Other_PLK_PLK2_PLK3_ST	P04637	TP53	Q9H4B4	PLK3	T150	L145P	145	Missense	distal	-5	no	9.520	10.568	EPSD	TCGA;ICGC;COSMIC	8.404	Up-regulation
Other_PLK_PLK2_PLK3_ST	P04637	TP53	Q9H4B4	PLK3	T150	Q144L	144	Missense	distal	-6	no	9.520	8.899	EPSD	TCGA;ICGC;COSMIC	8.404	Down-regulation
Other_PLK_PLK2_PLK3_ST	P04637	TP53	Q9H4B4	PLK3	T150	Q144H	144	Missense	distal	-6	no	9.520	10.515	EPSD	TCGA;ICGC;COSMIC	8.404	Up-regulation
Other_PLK_PLK2_PLK3_ST	P04637	TP53	Q9H4B4	PLK3	T150	G154V	154	Missense	distal	4	no	9.520	8.891	EPSD	TCGA;ICGC;COSMIC;GDSC;CCLE	8.404	Down-regulation
Other_PLK_PLK2_PLK3_ST	P04637	TP53	Q9H4B4	PLK3	T150	V157L	157	Missense	distal	7	no	9.520	9.655	EPSD	TCGA;ICGC;COSMIC	8.404	Up-regulation
Other_PLK_PLK2_PLK3_ST	P04637	TP53	Q9H4B4	PLK3	T150	P151R	151	Missense	proximal	1	no	9.520	8.767	EPSD	TCGA;ICGC;COSMIC	8.404	Down-regulation
Other_PLK_PLK2_PLK3_ST	P04637	TP53	Q9H4B4	PLK3	T150	Q144P	144	Missense	distal	-6	no	9.520	10.909	EPSD	TCGA;ICGC;COSMIC	8.404	Up-regulation
Other_PLK_PLK2_PLK3_ST	P04637	TP53	Q9H4B4	PLK3	T150	V143E	143	Missense	distal	-7	no	9.520	9.173	EPSD	TCGA;ICGC;COSMIC	8.404	Down-regulation
Other_PLK_PLK2_PLK3_ST	P04637	TP53	Q9H4B4	PLK3	T150	R156G	156	Missense	distal	6	no	9.520	10.031	EPSD	TCGA;ICGC;COSMIC	8.404	Up-regulation
Other_PLK_PLK2_PLK3_ST	P04637	TP53	Q9H4B4	PLK3	T150	P151L	151	Missense	proximal	1	no	9.520	9.609	EPSD	TCGA;ICGC;COSMIC	8.404	Up-regulation
Other_PLK_PLK2_PLK3_ST	P04637	TP53	Q9H4B4	PLK3	S183	H179R	179	Missense	distal	-4	no	12.054	11.253	EPSD	TCGA;ICGC;COSMIC;GDSC;CCLE	8.404	Down-regulation
Other_PLK_PLK2_PLK3_ST	P04637	TP53	Q9H4B4	PLK3	S183	C176F	176	Missense	distal	-7	no	12.054	12.313	EPSD	TCGA;ICGC;COSMIC;GDSC;CCLE	8.404	Up-regulation
Other_PLK_PLK2_PLK3_ST	P04637	TP53	Q9H4B4	PLK3	S183	R181H	181	Missense	proximal	-2	no	12.054	13.005	EPSD	TCGA;ICGC;COSMIC;CCLE	8.404	Up-regulation
Other_PLK_PLK2_PLK3_ST	P04637	TP53	Q9H4B4	PLK3	S183	G187S	187	Missense	distal	4	no	12.054	11.872	EPSD	TCGA;ICGC;COSMIC	8.404	Down-regulation
Other_PLK_PLK2_PLK3_ST	P04637	TP53	Q9H4B4	PLK3	S183	H179Y	179	Missense	distal	-4	no	12.054	10.980	EPSD	TCGA;ICGC;COSMIC	8.404	Down-regulation
Other_PLK_PLK2_PLK3_ST	P04637	TP53	Q9H4B4	PLK3	S183	C176Y	176	Missense	distal	-7	no	12.054	11.645	EPSD	TCGA;ICGC;COSMIC;GDSC;CCLE	8.404	Down-regulation
Other_PLK_PLK2_PLK3_ST	P04637	TP53	Q9H4B4	PLK3	S183	P190L	190	Missense	distal	7	no	12.054	11.799	EPSD	TCGA;ICGC;COSMIC;CCLE	8.404	Down-regulation
Other_PLK_PLK2_PLK3_ST	P04637	TP53	Q9H4B4	PLK3	S183	P177S	177	Missense	distal	-6	no	12.054	12.867	EPSD	TCGA;ICGC;COSMIC	8.404	Up-regulation
Other_PLK_PLK2_PLK3_ST	P04637	TP53	Q9H4B4	PLK3	S183	H178Q	178	Missense	distal	-5	no	12.054	11.455	EPSD	TCGA;ICGC;COSMIC	8.404	Down-regulation
Other_PLK_PLK2_PLK3_ST	P04637	TP53	Q9H4B4	PLK3	S183	E180K	180	Missense	distal	-3	no	12.054	8.981	EPSD	TCGA;ICGC;COSMIC;CCLE	8.404	Down-regulation
Other_PLK_PLK2_PLK3_ST	P04637	TP53	Q9H4B4	PLK3	S183	C176S	176	Missense	distal	-7	no	12.054	12.572	EPSD	TCGA;ICGC;COSMIC;GDSC;CCLE	8.404	Up-regulation
Other_PLK_PLK2_PLK3_ST	P04637	TP53	Q9H4B4	PLK3	S183	H179N	179	Missense	distal	-4	no	12.054	9.470	EPSD	TCGA;ICGC;COSMIC	8.404	Down-regulation
Other_PLK_PLK2_PLK3_ST	P04637	TP53	Q9H4B4	PLK3	S183	H179P	179	Missense	distal	-4	no	12.054	11.754	EPSD	TCGA;ICGC;COSMIC	8.404	Down-regulation
Other_PLK_PLK2_PLK3_ST	P04637	TP53	Q9H4B4	PLK3	S183	H179L	179	Missense	distal	-4	no	12.054	12.046	EPSD	TCGA;ICGC;COSMIC	8.404	Down-regulation
Other_PLK_PLK2_PLK3_ST	P04637	TP53	Q9H4B4	PLK3	S183	H179D	179	Missense	distal	-4	no	12.054	11.702	EPSD	TCGA;ICGC;COSMIC;GDSC;CCLE	8.404	Down-regulation
Other_PLK_PLK2_PLK3_ST	P04637	TP53	Q9H4B4	PLK3	S183	P190R	190	Missense	distal	7	no	12.054	11.662	EPSD	TCGA;ICGC;COSMIC	8.404	Down-regulation
Other_PLK_PLK2_PLK3_ST	P04637	TP53	Q9H4B4	PLK3	S183	P177R	177	Missense	distal	-6	no	12.054	10.778	EPSD	TCGA;ICGC;COSMIC	8.404	Down-regulation
Other_PLK_PLK2_PLK3_ST	P04637	TP53	Q9H4B4	PLK3	S183	P177H	177	Missense	distal	-6	no	12.054	11.660	EPSD	TCGA;ICGC;COSMIC	8.404	Down-regulation
Other_PLK_PLK2_PLK3_ST	P04637	TP53	Q9H4B4	PLK3	S183	C176W	176	Missense	distal	-7	no	12.054	12.719	EPSD	TCGA;ICGC;COSMIC;GDSC;CCLE	8.404	Up-regulation
Other_PLK_PLK2_PLK3_ST	P04637	TP53	Q9H4B4	PLK3	S183	H179Q	179	Missense	distal	-4	no	12.054	11.024	EPSD	TCGA;ICGC;COSMIC;GDSC;CCLE	8.404	Down-regulation
Other_PLK_PLK2_PLK3_ST	P04637	TP53	Q9H4B4	PLK3	S183	P177T	177	Missense	distal	-6	no	12.054	12.423	EPSD	TCGA;ICGC;COSMIC;GDSC;CCLE	8.404	Up-regulation
Other_PLK_PLK2_PLK3_ST	P04637	TP53	Q9H4B4	PLK3	S183	R181P	181	Missense	proximal	-2	no	12.054	13.253	EPSD	TCGA;ICGC;COSMIC;CCLE	8.404	Up-regulation
Other_PLK_PLK2_PLK3_ST	P04637	TP53	Q9H4B4	PLK3	S183	C176R	176	Missense	distal	-7	no	12.054	12.101	EPSD	TCGA;ICGC;COSMIC	8.404	Up-regulation
Other_PLK_PLK2_PLK3_ST	P04637	TP53	Q9H4B4	PLK3	S183	R181C	181	Missense	proximal	-2	no	12.054	12.140	EPSD	TCGA;ICGC;COSMIC;GDSC;CCLE	8.404	Up-regulation
Other_PLK_PLK2_PLK3_ST	P04637	TP53	Q9H4B4	PLK3	S183	P177L	177	Missense	distal	-6	no	12.054	10.043	EPSD	TCGA;ICGC;COSMIC;GDSC;CCLE	8.404	Down-regulation
Other_PLK_PLK2_PLK3_ST	P04637	TP53	Q9H4B4	PLK3	T304	A307V	307	Missense	distal	3	no	7.878	8.436	EPSD	TCGA;ICGC;COSMIC;GDSC	8.404	Gain
Other_PLK_PLK2_PLK3_ST	P04637	TP53	Q9H4B4	PLK3	S315	K319N	319	Missense	distal	4	no	11.511	10.486	EPSD	TCGA;ICGC;COSMIC	8.404	Down-regulation
Other_PLK_PLK2_PLK3_ST	P04637	TP53	Q9H4B4	PLK3	S315	K320E	320	Missense	distal	5	no	11.511	10.892	EPSD	TCGA;ICGC;COSMIC	8.404	Down-regulation
Other_PLK_PLK2_PLK3_ST	P04637	TP53	Q9H4B4	PLK3	S315	S315C	315	Missense	central	0	yes	11.511	0.000	EPSD	TCGA;ICGC;COSMIC	8.404	Loss
Other_PLK_PLK2_PLK3_ST	P14635	CCNB1	Q9H4B4	PLK3	S116	S116L	116	Missense	central	0	yes	8.529	0.000	EPSD	TCGA;ICGC;COSMIC	8.404	Loss
Other_PLK_PLK2_PLK3_ST	P14635	CCNB1	Q9H4B4	PLK3	S133	M130V	130	Missense	distal	-3	no	15.446	13.570	PhosphoSitePlus	TCGA;ICGC;COSMIC	8.404	Down-regulation
Other_PLK_PLK2_PLK3_ST	P14635	CCNB1	Q9H4B4	PLK3	S133	A136D	136	Missense	distal	3	no	15.446	16.272	PhosphoSitePlus	TCGA;ICGC;COSMIC	8.404	Up-regulation
Other_PLK_PLK2_PLK3_ST	P14635	CCNB1	Q9H4B4	PLK3	S133	T132I	132	Missense	proximal	-1	no	15.446	16.751	PhosphoSitePlus	TCGA;ICGC;COSMIC	8.404	Up-regulation
Other_PLK_PLK2_PLK3_ST	Q14790	CASP8	Q9H4B4	PLK3	S305	I298M	298	Missense	distal	-7	no	10.915	10.546	EPSD	TCGA;ICGC;COSMIC	8.404	Down-regulation
Other_PLK_PLK2_PLK3_ST	Q14790	CASP8	Q9H4B4	PLK3	S375	S375F	375	Missense	central	0	yes	9.500	0.000	EPSD	TCGA;COSMIC	8.404	Loss
Other_PLK_PLK2_PLK3_ST	P30304	CDC25A	Q9H4B4	PLK3	T80	D87Y	87	Missense	distal	7	no	16.479	17.451	PhosphoSitePlus	TCGA;ICGC;COSMIC	8.404	Up-regulation
Other_PLK_PLK2_PLK3_ST	P30304	CDC25A	Q9H4B4	PLK3	T80	R73K	73	Missense	distal	-7	no	16.479	16.557	PhosphoSitePlus	TCGA;ICGC;COSMIC	8.404	Up-regulation
Other_PLK_PLK2_PLK3_ST	P30304	CDC25A	Q9H4B4	PLK3	T80	E78K	78	Missense	proximal	-2	no	16.479	11.584	PhosphoSitePlus	TCGA;ICGC;COSMIC	8.404	Down-regulation
Other_PLK_PLK2_PLK3_ST	P30304	CDC25A	Q9H4B4	PLK3	S266	R270P	270	Missense	distal	4	no	8.413	9.487	EPSD	TCGA;ICGC;COSMIC;GDSC;CCLE	8.404	Up-regulation
Other_PLK_PLK2_PLK3_ST	P30304	CDC25A	Q9H4B4	PLK3	S279	P284T	284	Missense	distal	5	no	11.102	10.276	EPSD	TCGA;ICGC;COSMIC	8.404	Down-regulation
Other_PLK_PLK2_PLK3_ST	P30304	CDC25A	Q9H4B4	PLK3	S279	R275K	275	Missense	distal	-4	no	11.102	10.750	EPSD	TCGA;ICGC	8.404	Down-regulation
Other_PLK_PLK2_PLK3_ST	P30304	CDC25A	Q9H4B4	PLK3	S321	S317F	317	Missense	distal	-4	no	6.160	8.422	EPSD	TCGA;ICGC;COSMIC	8.404	Gain
Other_PLK_PLK2_PLK3_ST	P30304	CDC25A	Q9H4B4	PLK3	S513	R520H	520	Missense	distal	7	no	10.260	9.987	EPSD	TCGA;ICGC;COSMIC;GDSC;CCLE	8.404	Down-regulation
Other_PLK_PLK2_PLK3_ST	P30304	CDC25A	Q9H4B4	PLK3	S513	R520C	520	Missense	distal	7	no	10.260	9.588	EPSD	TCGA;ICGC	8.404	Down-regulation
Other_PLK_PLK2_PLK3_ST	P30304	CDC25A	Q9H4B4	PLK3	S519	R520H	520	Missense	proximal	1	no	9.895	10.533	EPSD	TCGA;ICGC;COSMIC;GDSC;CCLE	8.404	Up-regulation
Other_PLK_PLK2_PLK3_ST	P30304	CDC25A	Q9H4B4	PLK3	S519	R520C	520	Missense	proximal	1	no	9.895	10.284	EPSD	TCGA;ICGC	8.404	Up-regulation
Other_PLK_PLK2_PLK3_ST	Q16143	SNCB	Q9H4B4	PLK3	S118	E125K	125	Missense	distal	7	no	12.203	11.700	PhosphoSitePlus	TCGA;ICGC;COSMIC	8.404	Down-regulation
Other_PLK_PLK2_PLK3_ST	Q16143	SNCB	Q9H4B4	PLK3	S118	M112V	112	Missense	distal	-6	no	12.203	10.958	PhosphoSitePlus	TCGA;ICGC;COSMIC	8.404	Down-regulation
Other_PLK_PLK2_PLK3_ST	Q16143	SNCB	Q9H4B4	PLK3	S118	L111P	111	Missense	distal	-7	no	12.203	12.823	PhosphoSitePlus	TCGA;ICGC	8.404	Up-regulation
Other_PLK_PLK2_PLK3_ST	Q16143	SNCB	Q9H4B4	PLK3	S118	E120D	120	Missense	proximal	2	no	12.203	12.048	PhosphoSitePlus	TCGA;ICGC	8.404	Down-regulation
Other_PLK_PLK2_PLK3_ST	Q16143	SNCB	Q9H4B4	PLK3	S118	E125G	125	Missense	distal	7	no	12.203	11.068	PhosphoSitePlus	TCGA;ICGC	8.404	Down-regulation
Other_PLK_PLK2_PLK3_ST	Q07817	BCL2L1	Q9H4B4	PLK3	S49	A50V	50	Missense	proximal	1	no	16.063	15.459	PhosphoSitePlus	TCGA;ICGC;COSMIC	8.404	Down-regulation
Other_PLK_PLK2_PLK3_ST	P37840	SNCA	Q9H4B4	PLK3	S129	D135Y	135	Missense	distal	6	no	13.118	12.904	PhosphoSitePlus	TCGA;ICGC;COSMIC	8.404	Down-regulation
Other_PLK_PLK2_PLK3_ST	P37840	SNCA	Q9H4B4	PLK3	S129	S129F	129	Missense	central	0	yes	13.118	0.000	PhosphoSitePlus	TCGA;ICGC;COSMIC	8.404	Loss
CMGC_MAPK_JNK_MAPK10_ST	P01106	MYC	P53779	MAPK10	S161	S161L	161	Missense	central	0	yes	0.023	0.000	EPSD	TCGA;ICGC;COSMIC	0.000	Loss
CMGC_MAPK_JNK_MAPK10_ST	P05067	APP	P53779	MAPK10	S193	D194G	194	Missense	proximal	1	no	0.000	-0.002	EPSD	TCGA;ICGC;COSMIC	0.000	Loss
CMGC_MAPK_JNK_MAPK10_ST	P05067	APP	P53779	MAPK10	S206	S206L	206	Missense	central	0	yes	0.000	0.000	EPSD	TCGA;COSMIC	0.000	Loss
CMGC_MAPK_JNK_MAPK10_ST	P05067	APP	P53779	MAPK10	S587	P584S	584	Missense	distal	-3	no	0.002	0.001	EPSD	TCGA;COSMIC	0.000	Down-regulation
CMGC_MAPK_JNK_MAPK10_ST	P38936	CDKN1A	P53779	MAPK10	S31	R32H	32	Missense	proximal	1	no	-0.001	0.000	EPSD	TCGA;ICGC;COSMIC	0.000	Gain
CMGC_MAPK_JNK_MAPK10_ST	P38936	CDKN1A	P53779	MAPK10	T57	P58L	58	Missense	proximal	1	no	0.023	-0.002	EPSD	TCGA;ICGC;COSMIC	0.000	Loss
CMGC_MAPK_JNK_MAPK10_ST	P54259	ATN1	P53779	MAPK10	T64	P65L	65	Missense	proximal	1	no	0.024	-0.002	EPSD	TCGA;ICGC;COSMIC	0.000	Loss
CMGC_MAPK_JNK_MAPK10_ST	P54259	ATN1	P53779	MAPK10	S103	S103C	103	Missense	central	0	yes	0.000	0.000	EPSD	TCGA;ICGC;COSMIC	0.000	Loss
CMGC_MAPK_JNK_MAPK10_ST	P54259	ATN1	P53779	MAPK10	S263	S264C	264	Missense	proximal	1	no	-0.002	0.000	EPSD	TCGA;ICGC;COSMIC	0.000	Gain
CMGC_MAPK_JNK_MAPK10_ST	P54259	ATN1	P53779	MAPK10	S632	S632F	632	Missense	central	0	yes	0.023	0.000	EPSD	TCGA;ICGC;COSMIC	0.000	Loss
CMGC_MAPK_JNK_MAPK10_ST	P54259	ATN1	P53779	MAPK10	S661	S661A	661	Missense	central	0	yes	0.022	0.000	EPSD	TCGA;ICGC;COSMIC	0.000	Loss
Other_NEK_NEK1_NEK1_ST	P21796	VDAC1	Q96PY6	NEK1	T258	L251V	251	Missense	distal	-7	no	2.700	2.160	EPSD	TCGA;ICGC;COSMIC	2.106	Down-regulation
Other_NEK_NEK1_NEK1_ST	P21796	VDAC1	Q96PY6	NEK1	T258	K256T	256	Missense	proximal	-2	no	2.700	2.619	EPSD	TCGA;ICGC;COSMIC	2.106	Down-regulation
Other_NEK_NEK1_NEK1_ST	P40337	VHL	Q96PY6	NEK1	S80	R79G	79	Missense	proximal	-1	no	1.943	2.146	EPSD	TCGA;ICGC;COSMIC	2.106	Gain
Other_NEK_NEK1_NEK1_ST	P40337	VHL	Q96PY6	NEK1	T100	R107P	107	Missense	distal	7	no	4.611	4.613	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	2.106	Up-regulation
Other_NEK_NEK1_NEK1_ST	P40337	VHL	Q96PY6	NEK1	T105	R107P	107	Missense	proximal	2	no	4.846	4.840	PhosphoSitePlus;EPSD	TCGA;ICGC;COSMIC	2.106	Down-regulation
Other_NEK_NEK1_NEK1_ST	P40337	VHL	Q96PY6	NEK1	T105	H110P	110	Missense	distal	5	no	4.846	4.880	PhosphoSitePlus;EPSD	TCGA;ICGC;COSMIC;GDSC	2.106	Up-regulation
Other_NEK_NEK1_NEK1_ST	P40337	VHL	Q96PY6	NEK1	T105	S111N	111	Missense	distal	6	no	4.846	4.902	PhosphoSitePlus;EPSD	TCGA;ICGC;COSMIC;CCLE	2.106	Up-regulation
Other_NEK_NEK1_NEK1_ST	P40337	VHL	Q96PY6	NEK1	S168	V165D	165	Missense	distal	-3	no	4.486	4.532	EPSD;PhosphoSitePlus	TCGA;COSMIC	2.106	Up-regulation
Other_NEK_NEK1_NEK1_ST	P40337	VHL	Q96PY6	NEK1	S168	L169P	169	Missense	proximal	1	no	4.486	4.460	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	2.106	Down-regulation
Other_NEK_NEK1_NEK1_ST	P40337	VHL	Q96PY6	NEK1	S168	R161P	161	Missense	distal	-7	no	4.486	4.570	EPSD;PhosphoSitePlus	TCGA;COSMIC	2.106	Up-regulation
Other_NEK_NEK1_NEK1_ST	P40337	VHL	Q96PY6	NEK1	S168	C162R	162	Missense	distal	-6	no	4.486	4.461	EPSD;PhosphoSitePlus	TCGA;COSMIC	2.106	Down-regulation
Other_NEK_NEK1_NEK1_ST	P40337	VHL	Q96PY6	NEK1	S168	R167G	167	Missense	proximal	-1	no	4.486	4.688	EPSD;PhosphoSitePlus	TCGA;COSMIC	2.106	Up-regulation
Other_NEK_NEK1_NEK1_ST	P40337	VHL	Q96PY6	NEK1	S168	R161Q	161	Missense	distal	-7	no	4.486	4.453	EPSD;PhosphoSitePlus	TCGA;COSMIC	2.106	Down-regulation
Other_NEK_NEK1_NEK1_ST	P40337	VHL	Q96PY6	NEK1	S168	R167W	167	Missense	proximal	-1	no	4.486	4.353	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	2.106	Down-regulation
Other_NEK_NEK1_NEK1_ST	P40337	VHL	Q96PY6	NEK1	S183	D190Y	190	Missense	distal	7	no	3.991	3.985	EPSD;PhosphoSitePlus	TCGA;COSMIC	2.106	Down-regulation
Other_NEK_NEK1_NEK1_ST	P40337	VHL	Q96PY6	NEK1	S183	L188R	188	Missense	distal	5	no	3.991	3.787	EPSD;PhosphoSitePlus	TCGA;COSMIC	2.106	Down-regulation
Other_NEK_NEK1_NEK1_ST	P40337	VHL	Q96PY6	NEK1	S183	L184P	184	Missense	proximal	1	no	3.991	3.964	EPSD;PhosphoSitePlus	TCGA;COSMIC	2.106	Down-regulation
Other_NEK_NEK1_NEK1_ST	P40337	VHL	Q96PY6	NEK1	S183	L188P	188	Missense	distal	5	no	3.991	3.931	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	2.106	Down-regulation
Other_NEK_NEK1_NEK1_ST	P40337	VHL	Q96PY6	NEK1	S183	L178P	178	Missense	distal	-5	no	3.991	3.973	EPSD;PhosphoSitePlus	TCGA;COSMIC	2.106	Down-regulation
Other_NEK_NEK1_NEK1_ST	P40337	VHL	Q96PY6	NEK1	T202	R205C	205	Missense	distal	3	no	3.643	3.502	EPSD;PhosphoSitePlus	TCGA;COSMIC	2.106	Down-regulation
Other_NEK_NEK1_NEK1_ST	Q92698	RAD54L	Q96PY6	NEK1	S572	G576R	576	Missense	distal	4	no	4.189	4.056	PhosphoSitePlus	TCGA;ICGC;COSMIC	2.106	Down-regulation
Other_NEK_NEK1_NEK1_ST	Q92698	RAD54L	Q96PY6	NEK1	S572	M570V	570	Missense	proximal	-2	no	4.189	4.188	PhosphoSitePlus	TCGA;ICGC;COSMIC	2.106	Down-regulation
Other_NEK_NEK1_NEK1_ST	O14777	NDC80	Q96PY6	NEK1	T34	F40L	40	Missense	distal	6	no	2.401	2.373	EPSD	TCGA;ICGC;COSMIC	2.106	Down-regulation
CMGC_CDK_CCRK_CDK20_ST	P24941	CDK2	Q8IZL9	CDK20	T160	V163M	163	Missense	distal	3	no	5.811	5.927	PhosphoSitePlus	TCGA;ICGC;COSMIC	1.958	Up-regulation
CMGC_CDK_CCRK_CDK20_ST	P24941	CDK2	Q8IZL9	CDK20	T160	P155H	155	Missense	distal	-5	no	5.811	5.289	PhosphoSitePlus	TCGA	1.958	Down-regulation
TK_Axl_AXL_Y	Q92556	ELMO1	P30530	AXL	Y18	A11T	11	Missense	distal	-7	no	0.001	0.002	EPSD	TCGA;ICGC	0.002	Gain
TK_Axl_AXL_Y	Q92556	ELMO1	P30530	AXL	Y352	K349R	349	Missense	distal	-3	no	0.002	0.001	EPSD	TCGA;ICGC;COSMIC	0.002	Loss
TK_Axl_AXL_Y	Q92556	ELMO1	P30530	AXL	Y720	I713T	713	Missense	distal	-7	no	0.006	0.005	PhosphoSitePlus;EPSD	TCGA;ICGC;COSMIC	0.002	Down-regulation
TK_Axl_AXL_Y	Q92556	ELMO1	P30530	AXL	Y724	D725H	725	Missense	proximal	1	no	0.002	0.001	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC;CCLE	0.002	Loss
TK_Axl_AXL_Y	P07948	LYN	P30530	AXL	Y306	V303M	303	Missense	distal	-3	no	0.003	0.002	EPSD	TCGA;ICGC;COSMIC	0.002	Down-regulation
TK_Axl_AXL_Y	P07948	LYN	P30530	AXL	Y492	D498Y	498	Missense	distal	6	no	0.003	0.004	EPSD	TCGA;ICGC;COSMIC	0.002	Up-regulation
TK_Axl_AXL_Y	P08631	HCK	P30530	AXL	Y411	Y411C	411	Missense	central	0	yes	0.011	0.000	PhosphoSitePlus	TCGA	0.002	Loss
TK_Axl_AXL_Y	P31749	AKT1	P30530	AXL	Y417	Y417C	417	Missense	central	0	yes	0.004	0.000	EPSD	TCGA;ICGC;COSMIC	0.002	Loss
TK_Axl_AXL_Y	P42229	STAT5A	P30530	AXL	Y114	R107H	107	Missense	distal	-7	no	0.002	0.001	EPSD	TCGA;ICGC;COSMIC	0.002	Loss
TK_Axl_AXL_Y	P40763	STAT3	P30530	AXL	Y686	Y686D	686	Missense	central	0	yes	0.004	0.000	EPSD	TCGA;ICGC	0.002	Loss
TK_Axl_AXL_Y	P06239	LCK	P30530	AXL	Y470	E467D	467	Missense	distal	-3	no	0.003	0.004	EPSD	TCGA;ICGC;COSMIC;GDSC;CCLE	0.002	Up-regulation
TK_Axl_AXL_Y	P07947	YES1	P30530	AXL	Y345	Y345S	345	Missense	central	0	yes	0.004	0.000	EPSD	TCGA;COSMIC	0.002	Loss
TK_Axl_AXL_Y	P07947	YES1	P30530	AXL	Y446	T439A	439	Missense	distal	-7	no	0.002	0.001	EPSD	TCGA;COSMIC	0.002	Loss
CAMK_DAPK_DAPK_DAPK3_ST	Q96A00	PPP1R14A	O43293	DAPK3	T38	R36C	36	Missense	proximal	-2	no	9.447	6.984	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	6.449	Down-regulation
CAMK_DAPK_DAPK_DAPK3_ST	Q96A00	PPP1R14A	O43293	DAPK3	T38	R44W	44	Missense	distal	6	no	9.447	9.474	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	6.449	Up-regulation
CAMK_DAPK_DAPK_DAPK3_ST	Q96A00	PPP1R14A	O43293	DAPK3	S128	P129T	129	Missense	proximal	1	no	6.517	6.493	EPSD	TCGA;COSMIC	6.449	Down-regulation
CAMK_DAPK_DAPK_DAPK3_ST	O43293	DAPK3	O43293	DAPK3	S50	L49P	49	Missense	proximal	-1	no	10.604	10.629	EPSD	TCGA;ICGC;COSMIC	6.449	Up-regulation
CAMK_DAPK_DAPK_DAPK3_ST	O43293	DAPK3	O43293	DAPK3	S50	R47C	47	Missense	distal	-3	no	10.604	4.500	EPSD	TCGA;ICGC;COSMIC	6.449	Loss
CAMK_DAPK_DAPK_DAPK3_ST	O43293	DAPK3	O43293	DAPK3	S50	R48C	48	Missense	proximal	-2	no	10.604	8.141	EPSD	TCGA;ICGC;COSMIC	6.449	Down-regulation
CAMK_DAPK_DAPK_DAPK3_ST	O43293	DAPK3	O43293	DAPK3	S50	R48H	48	Missense	proximal	-2	no	10.604	8.852	EPSD	TCGA;ICGC	6.449	Down-regulation
CAMK_DAPK_DAPK_DAPK3_ST	O43293	DAPK3	O43293	DAPK3	S50	S52I	52	Missense	proximal	2	no	10.604	10.688	EPSD	TCGA;ICGC;COSMIC	6.449	Up-regulation
CAMK_DAPK_DAPK_DAPK3_ST	O43293	DAPK3	O43293	DAPK3	S50	R53W	53	Missense	distal	3	no	10.604	10.678	EPSD	TCGA;ICGC;COSMIC	6.449	Up-regulation
CAMK_DAPK_DAPK_DAPK3_ST	O43293	DAPK3	O43293	DAPK3	S50	I44M	44	Missense	distal	-6	no	10.604	10.550	EPSD	TCGA;ICGC;COSMIC	6.449	Down-regulation
CAMK_DAPK_DAPK_DAPK3_ST	O43293	DAPK3	O43293	DAPK3	T180	F174L	174	Missense	distal	-6	no	9.757	9.606	EPSD;PhosphoSitePlus	TCGA;ICGC	6.449	Down-regulation
CAMK_DAPK_DAPK_DAPK3_ST	O43293	DAPK3	O43293	DAPK3	T180	I177M	177	Missense	distal	-3	no	9.757	9.802	EPSD;PhosphoSitePlus	TCGA;ICGC	6.449	Up-regulation
CAMK_DAPK_DAPK_DAPK3_ST	O43293	DAPK3	O43293	DAPK3	T180	N176I	176	Missense	distal	-4	no	9.757	9.536	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	6.449	Down-regulation
CAMK_DAPK_DAPK_DAPK3_ST	O43293	DAPK3	O43293	DAPK3	T180	N176K	176	Missense	distal	-4	no	9.757	9.922	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	6.449	Up-regulation
CAMK_DAPK_DAPK_DAPK3_ST	O43293	DAPK3	O43293	DAPK3	T180	E182K	182	Missense	proximal	2	no	9.757	9.722	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	6.449	Down-regulation
CAMK_DAPK_DAPK_DAPK3_ST	O43293	DAPK3	O43293	DAPK3	T265	D259Y	259	Missense	distal	-6	no	12.236	12.198	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	6.449	Down-regulation
CAMK_DAPK_DAPK_DAPK3_ST	O43293	DAPK3	O43293	DAPK3	T299	E304K	304	Missense	distal	5	no	12.364	12.504	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	6.449	Up-regulation
CAMK_DAPK_DAPK_DAPK3_ST	O43293	DAPK3	O43293	DAPK3	T306	E304K	304	Missense	proximal	-2	no	11.911	12.441	PhosphoSitePlus;EPSD	TCGA;ICGC;COSMIC	6.449	Up-regulation
CAMK_DAPK_DAPK_DAPK3_ST	O43293	DAPK3	O43293	DAPK3	T306	S309L	309	Missense	distal	3	no	11.911	11.719	PhosphoSitePlus;EPSD	TCGA;ICGC	6.449	Down-regulation
CAMK_DAPK_DAPK_DAPK3_ST	O43293	DAPK3	O43293	DAPK3	S311	E304K	304	Missense	distal	-7	no	11.084	12.075	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	6.449	Up-regulation
CAMK_DAPK_DAPK_DAPK3_ST	O43293	DAPK3	O43293	DAPK3	S311	S309L	309	Missense	proximal	-2	no	11.084	10.281	EPSD;PhosphoSitePlus	TCGA;ICGC	6.449	Down-regulation
CAMK_DAPK_DAPK_DAPK3_ST	P40429	RPL13A	O43293	DAPK3	T64	N65K	65	Missense	proximal	1	no	9.982	9.942	EPSD	TCGA;ICGC;COSMIC	6.449	Down-regulation
CAMK_DAPK_DAPK_DAPK3_ST	P40429	RPL13A	O43293	DAPK3	T64	R59L	59	Missense	distal	-5	no	9.982	7.141	EPSD	TCGA;ICGC;COSMIC	6.449	Down-regulation
CAMK_DAPK_DAPK_DAPK3_ST	P40429	RPL13A	O43293	DAPK3	T64	R59C	59	Missense	distal	-5	no	9.982	7.194	EPSD	TCGA;ICGC;COSMIC	6.449	Down-regulation
CAMK_DAPK_DAPK_DAPK3_ST	P40429	RPL13A	O43293	DAPK3	T64	L58F	58	Missense	distal	-6	no	9.982	10.133	EPSD	TCGA;ICGC;COSMIC	6.449	Up-regulation
CAMK_DAPK_DAPK_DAPK3_ST	P40429	RPL13A	O43293	DAPK3	T64	R61W	61	Missense	distal	-3	no	9.982	4.090	EPSD	TCGA;ICGC;COSMIC	6.449	Loss
CAMK_DAPK_DAPK_DAPK3_ST	P40429	RPL13A	O43293	DAPK3	T64	R68Q	68	Missense	distal	4	no	9.982	10.019	EPSD	TCGA;ICGC;COSMIC	6.449	Up-regulation
CAMK_DAPK_DAPK_DAPK3_ST	P40429	RPL13A	O43293	DAPK3	S77	F80L	80	Missense	distal	3	no	11.310	10.863	PhosphoSitePlus	TCGA;ICGC	6.449	Down-regulation
CAMK_DAPK_DAPK_DAPK3_ST	O14950	MYL12B	O43293	DAPK3	T19	R17C	17	Missense	proximal	-2	no	10.367	7.903	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	6.449	Down-regulation
CAMK_DAPK_DAPK_DAPK3_ST	O14950	MYL12B	O43293	DAPK3	S20	R17C	17	Missense	distal	-3	no	11.851	5.747	PhosphoSitePlus;EPSD	TCGA;ICGC;COSMIC	6.449	Loss
CAMK_DAPK_DAPK_DAPK3_ST	P04637	TP53	O43293	DAPK3	S215	D208N	208	Missense	distal	-7	no	5.367	6.839	EPSD	TCGA;ICGC;COSMIC	6.449	Gain
CAMK_DAPK_DAPK_DAPK3_ST	P04637	TP53	O43293	DAPK3	S269	G266R	266	Missense	distal	-3	no	2.220	7.222	EPSD	TCGA;ICGC;COSMIC;GDSC;CCLE	6.449	Gain
CAMK_DAPK_DAPK_DAPK3_ST	P04637	TP53	O43293	DAPK3	S362	A355T	355	Missense	distal	-7	no	7.685	8.832	EPSD	TCGA;ICGC;COSMIC	6.449	Up-regulation
CAMK_DAPK_DAPK_DAPK3_ST	P38936	CDKN1A	O43293	DAPK3	S31	D33N	33	Missense	proximal	2	no	6.680	6.583	EPSD	TCGA;ICGC;COSMIC	6.449	Down-regulation
CAMK_DAPK_DAPK_DAPK3_ST	P38936	CDKN1A	O43293	DAPK3	S31	R32H	32	Missense	proximal	1	no	6.680	6.714	EPSD	TCGA;ICGC;COSMIC	6.449	Up-regulation
CAMK_DAPK_DAPK_DAPK3_ST	P38936	CDKN1A	O43293	DAPK3	S31	A36V	36	Missense	distal	5	no	6.680	6.482	EPSD	TCGA;ICGC;COSMIC	6.449	Down-regulation
CAMK_DAPK_DAPK_DAPK3_ST	P38936	CDKN1A	O43293	DAPK3	T97	R94W	94	Missense	distal	-3	no	11.362	5.469	EPSD	TCGA;ICGC;COSMIC	6.449	Loss
CAMK_DAPK_DAPK_DAPK3_ST	P38936	CDKN1A	O43293	DAPK3	T97	R93S	93	Missense	distal	-4	no	11.362	10.994	EPSD	TCGA;ICGC;COSMIC	6.449	Down-regulation
CAMK_DAPK_DAPK_DAPK3_ST	P38936	CDKN1A	O43293	DAPK3	T97	R94P	94	Missense	distal	-3	no	11.362	7.033	EPSD	TCGA;ICGC;COSMIC	6.449	Down-regulation
CAMK_DAPK_DAPK_DAPK3_ST	P38936	CDKN1A	O43293	DAPK3	T97	P95S	95	Missense	proximal	-2	no	11.362	11.648	EPSD	TCGA;ICGC;COSMIC	6.449	Up-regulation
CAMK_DAPK_DAPK_DAPK3_ST	P38936	CDKN1A	O43293	DAPK3	S98	R94W	94	Missense	distal	-4	no	6.600	6.135	EPSD	TCGA;ICGC;COSMIC	6.449	Loss
CAMK_DAPK_DAPK_DAPK3_ST	P38936	CDKN1A	O43293	DAPK3	S98	R93S	93	Missense	distal	-5	no	6.600	4.668	EPSD	TCGA;ICGC;COSMIC	6.449	Loss
CAMK_DAPK_DAPK_DAPK3_ST	P38936	CDKN1A	O43293	DAPK3	S98	R94P	94	Missense	distal	-4	no	6.600	6.328	EPSD	TCGA;ICGC;COSMIC	6.449	Loss
CAMK_DAPK_DAPK_DAPK3_ST	P38936	CDKN1A	O43293	DAPK3	S98	P95S	95	Missense	distal	-3	no	6.600	6.296	EPSD	TCGA;ICGC;COSMIC	6.449	Loss
CAMK_DAPK_DAPK_DAPK3_ST	P38936	CDKN1A	O43293	DAPK3	T145	D149H	149	Missense	distal	4	no	14.198	14.189	PhosphoSitePlus	TCGA;ICGC;COSMIC	6.449	Down-regulation
CAMK_DAPK_DAPK_DAPK3_ST	P38936	CDKN1A	O43293	DAPK3	T145	R142W	142	Missense	distal	-3	no	14.198	8.305	PhosphoSitePlus	TCGA;ICGC;COSMIC;GDSC;CCLE	6.449	Down-regulation
CAMK_DAPK_DAPK_DAPK3_ST	P38936	CDKN1A	O43293	DAPK3	S146	S153C	153	Missense	distal	7	no	6.558	6.667	EPSD	TCGA;ICGC;COSMIC	6.449	Up-regulation
CAMK_DAPK_DAPK_DAPK3_ST	P38936	CDKN1A	O43293	DAPK3	S146	D149H	149	Missense	distal	3	no	6.558	6.758	EPSD	TCGA;ICGC;COSMIC	6.449	Up-regulation
CAMK_DAPK_DAPK_DAPK3_ST	P38936	CDKN1A	O43293	DAPK3	S146	R142W	142	Missense	distal	-4	no	6.558	6.094	EPSD	TCGA;ICGC;COSMIC;GDSC;CCLE	6.449	Loss
CAMK_DAPK_DAPK_DAPK3_ST	Q14457	BECN1	O43293	DAPK3	S90	P84L	84	Missense	distal	-6	no	10.465	10.778	PhosphoSitePlus	TCGA;ICGC;COSMIC	6.449	Up-regulation
CAMK_DAPK_DAPK_DAPK3_ST	Q14457	BECN1	O43293	DAPK3	T91	P84L	84	Missense	distal	-7	no	7.709	7.312	EPSD	TCGA;ICGC;COSMIC	6.449	Down-regulation
CAMK_DAPK_DAPK_DAPK3_ST	Q14457	BECN1	O43293	DAPK3	T91	T98P	98	Missense	distal	7	no	7.709	7.741	EPSD	TCGA;ICGC;COSMIC	6.449	Up-regulation
CAMK_DAPK_DAPK_DAPK3_ST	Q14457	BECN1	O43293	DAPK3	T98	T98P	98	Missense	central	0	yes	7.390	0.000	EPSD	TCGA;ICGC;COSMIC	6.449	Loss
TK_FGFR_FGFR2_Y	P21802	FGFR2	P21802	FGFR2	Y586	P582Q	582	Missense	distal	-4	no	3.301	3.349	EPSD	TCGA;COSMIC	1.189	Up-regulation
TK_FGFR_FGFR2_Y	P21802	FGFR2	P21802	FGFR2	Y588	P582Q	582	Missense	distal	-6	no	3.238	3.390	EPSD	TCGA;COSMIC	1.189	Up-regulation
TK_FGFR_FGFR2_Y	P35222	CTNNB1	P21802	FGFR2	Y142	V136A	136	Missense	distal	-6	no	3.637	3.339	PhosphoSitePlus	TCGA;COSMIC	1.189	Down-regulation
TK_FGFR_FGFR2_Y	P35222	CTNNB1	P21802	FGFR2	Y142	I140N	140	Missense	proximal	-2	no	3.637	3.638	PhosphoSitePlus	TCGA	1.189	Up-regulation
TK_FGFR_FGFR2_Y	P35222	CTNNB1	P21802	FGFR2	Y142	D144E	144	Missense	proximal	2	no	3.637	3.524	PhosphoSitePlus	TCGA;COSMIC	1.189	Down-regulation
TK_FGFR_FGFR2_Y	P35222	CTNNB1	P21802	FGFR2	Y748	P744T	744	Missense	distal	-4	no	1.346	1.277	EPSD	TCGA;COSMIC	1.189	Down-regulation
TK_FGFR_FGFR2_Y	P35222	CTNNB1	P21802	FGFR2	Y748	P744S	744	Missense	distal	-4	no	1.346	1.161	EPSD	TCGA	1.189	Loss
TK_FGFR_FGFR2_Y	P60484	PTEN	P21802	FGFR2	Y240	R233Q	233	Missense	distal	-7	no	3.649	3.533	PhosphoSitePlus	TCGA;ICGC;COSMIC;GDSC;CCLE	1.189	Down-regulation
TK_FGFR_FGFR2_Y	P60484	PTEN	P21802	FGFR2	Y240	P246L	246	Missense	distal	6	no	3.649	3.254	PhosphoSitePlus	TCGA;ICGC;COSMIC;CCLE	1.189	Down-regulation
TK_FGFR_FGFR2_Y	P60484	PTEN	P21802	FGFR2	Y240	M239R	239	Missense	proximal	-1	no	3.649	3.632	PhosphoSitePlus	TCGA;ICGC;COSMIC	1.189	Down-regulation
TK_FGFR_FGFR2_Y	P60484	PTEN	P21802	FGFR2	Y240	M239V	239	Missense	proximal	-1	no	3.649	3.626	PhosphoSitePlus	TCGA;ICGC;COSMIC	1.189	Down-regulation
TK_FGFR_FGFR2_Y	P60484	PTEN	P21802	FGFR2	Y240	P246R	246	Missense	distal	6	no	3.649	3.102	PhosphoSitePlus	TCGA;ICGC;COSMIC	1.189	Down-regulation
TK_FGFR_FGFR2_Y	P60484	PTEN	P21802	FGFR2	Y240	L247F	247	Missense	distal	7	no	3.649	3.612	PhosphoSitePlus	TCGA;ICGC;COSMIC	1.189	Down-regulation
TK_FGFR_FGFR2_Y	P60484	PTEN	P21802	FGFR2	Y240	P246S	246	Missense	distal	6	no	3.649	2.985	PhosphoSitePlus	TCGA;ICGC;COSMIC	1.189	Down-regulation
TK_FGFR_FGFR2_Y	P60484	PTEN	P21802	FGFR2	Y240	Q245P	245	Missense	distal	5	no	3.649	3.072	PhosphoSitePlus	TCGA;ICGC;COSMIC	1.189	Down-regulation
TK_FGFR_FGFR2_Y	P60484	PTEN	P21802	FGFR2	Y240	Q245E	245	Missense	distal	5	no	3.649	3.559	PhosphoSitePlus	TCGA;ICGC;COSMIC	1.189	Down-regulation
TK_FGFR_FGFR2_Y	P60484	PTEN	P21802	FGFR2	Y240	F241S	241	Missense	proximal	1	no	3.649	3.630	PhosphoSitePlus	TCGA;ICGC;COSMIC;CCLE	1.189	Down-regulation
TK_FGFR_FGFR2_Y	P62993	GRB2	P21802	FGFR2	Y7	Y7D	7	Missense	central	0	yes	1.633	0.000	EPSD	TCGA;ICGC;COSMIC	1.189	Loss
TK_FGFR_FGFR2_Y	P62993	GRB2	P21802	FGFR2	Y7	A13V	13	Missense	distal	6	no	1.633	1.382	EPSD	TCGA;ICGC	1.189	Down-regulation
CAMK_CAMKL_BRSK_BRSK1_ST	Q8TDC3	BRSK1	Q8TDC3-2	BRSK1	T189	E188K	188	Missense	proximal	-1	no	1.236	1.194	EPSD	TCGA;COSMIC	0.579	Down-regulation
CAMK_CAMKL_BRSK_BRSK1_ST	Q8TDC3	BRSK1	Q8TDC3-2	BRSK1	T189	G192A	192	Missense	distal	3	no	1.236	1.210	EPSD	TCGA;COSMIC	0.579	Down-regulation
CAMK_CAMKL_BRSK_BRSK1_ST	Q8TDC3	BRSK1	Q8TDC3-2	BRSK1	S193	E188K	188	Missense	distal	-5	no	1.181	1.148	EPSD	TCGA;COSMIC	0.579	Down-regulation
CAMK_CAMKL_BRSK_BRSK1_ST	Q8TDC3	BRSK1	Q8TDC3-2	BRSK1	S193	G192A	192	Missense	proximal	-1	no	1.181	1.134	EPSD	TCGA;COSMIC	0.579	Down-regulation
CAMK_CAMKL_BRSK_BRSK1_ST	Q8TDC3	BRSK1	Q8TDC3-2	BRSK1	S260	M265K	265	Missense	distal	5	no	0.542	0.594	EPSD	TCGA;COSMIC	0.579	Gain
CAMK_CAMKL_BRSK_BRSK1_ST	Q8TDC3	BRSK1	Q8TDC3-2	BRSK1	S260	R263G	263	Missense	distal	3	no	0.542	0.608	EPSD	TCGA;COSMIC	0.579	Gain
CAMK_CAMKL_BRSK_BRSK1_ST	Q8TDC3	BRSK1	Q8TDC3-2	BRSK1	S388	R389C	389	Missense	proximal	1	no	0.731	0.729	EPSD	TCGA;COSMIC	0.579	Down-regulation
CAMK_CAMKL_BRSK_BRSK1_ST	Q8TDC3	BRSK1	Q8TDC3-2	BRSK1	S388	V382A	382	Missense	distal	-6	no	0.731	0.658	EPSD	TCGA;COSMIC	0.579	Down-regulation
CAMK_CAMKL_BRSK_BRSK1_ST	Q8TDC3	BRSK1	Q8TDC3-2	BRSK1	S388	R394L	394	Missense	distal	6	no	0.731	0.807	EPSD	TCGA;COSMIC	0.579	Up-regulation
CAMK_CAMKL_BRSK_BRSK1_ST	Q8TDC3	BRSK1	Q8TDC3-2	BRSK1	S388	G391V	391	Missense	distal	3	no	0.731	0.674	EPSD	TCGA;COSMIC	0.579	Down-regulation
CAMK_CAMKL_BRSK_BRSK1_ST	Q8TDC3	BRSK1	Q8TDC3-2	BRSK1	S388	R381C	381	Missense	distal	-7	no	0.731	0.740	EPSD	TCGA;COSMIC	0.579	Up-regulation
CAMK_CAMKL_BRSK_BRSK1_ST	Q8TDC3	BRSK1	Q8TDC3-2	BRSK1	S388	R381H	381	Missense	distal	-7	no	0.731	0.738	EPSD	TCGA;COSMIC	0.579	Up-regulation
CAMK_CAMKL_BRSK_BRSK1_ST	Q8TDC3	BRSK1	Q8TDC3-2	BRSK1	S404	D407N	407	Missense	distal	3	no	0.565	0.616	EPSD	TCGA;COSMIC	0.579	Gain
CAMK_CAMKL_BRSK_BRSK1_ST	Q8TDC3	BRSK1	Q8TDC3-2	BRSK1	S404	G411S	411	Missense	distal	7	no	0.565	0.581	EPSD	TCGA;COSMIC	0.579	Gain
CAMK_CAMKL_BRSK_BRSK1_ST	Q8TDC3	BRSK1	Q8TDC3-2	BRSK1	T406	S404N	404	Missense	proximal	-2	no	0.778	0.631	EPSD	TCGA;COSMIC	0.579	Down-regulation
CAMK_CAMKL_BRSK_BRSK1_ST	Q8TDC3	BRSK1	Q8TDC3-2	BRSK1	T406	L403P	403	Missense	distal	-3	no	0.778	0.772	EPSD	TCGA;COSMIC	0.579	Down-regulation
CAMK_CAMKL_BRSK_BRSK1_ST	Q8TDC3	BRSK1	Q8TDC3-2	BRSK1	T406	D407N	407	Missense	proximal	1	no	0.778	0.743	EPSD	TCGA;COSMIC	0.579	Down-regulation
CAMK_CAMKL_BRSK_BRSK1_ST	Q8TDC3	BRSK1	Q8TDC3-2	BRSK1	T406	G411S	411	Missense	distal	5	no	0.778	0.697	EPSD	TCGA;COSMIC	0.579	Down-regulation
CAMK_CAMKL_BRSK_BRSK1_ST	Q8TDC3	BRSK1	Q8TDC3-2	BRSK1	S442	S443I	443	Missense	proximal	1	no	0.607	0.534	EPSD	TCGA;COSMIC	0.579	Loss
CAMK_CAMKL_BRSK_BRSK1_ST	Q8TDC3	BRSK1	Q8TDC3-2	BRSK1	S442	S442F	442	Missense	central	0	yes	0.607	0.000	EPSD	TCGA;COSMIC	0.579	Loss
CAMK_CAMKL_BRSK_BRSK1_ST	Q8TDC3	BRSK1	Q8TDC3-2	BRSK1	T575	A576T	576	Missense	proximal	1	no	0.588	0.593	EPSD	TCGA;COSMIC	0.579	Up-regulation
CAMK_CAMKL_BRSK_BRSK1_ST	Q8TDC3	BRSK1	Q8TDC3-2	BRSK1	T575	Q572H	572	Missense	distal	-3	no	0.588	0.592	EPSD	TCGA;COSMIC	0.579	Up-regulation
CAMK_CAMKL_BRSK_BRSK1_ST	Q8TDC3	BRSK1	Q8TDC3-2	BRSK1	S580	E585K	585	Missense	distal	5	no	0.639	0.657	EPSD	TCGA;COSMIC	0.579	Up-regulation
CAMK_CAMKL_BRSK_BRSK1_ST	Q8TDC3	BRSK1	Q8TDC3-2	BRSK1	T583	A576T	576	Missense	distal	-7	no	0.653	0.655	EPSD	TCGA;COSMIC	0.579	Up-regulation
CAMK_CAMKL_BRSK_BRSK1_ST	Q8TDC3	BRSK1	Q8TDC3-2	BRSK1	T583	E585K	585	Missense	proximal	2	no	0.653	0.639	EPSD	TCGA;COSMIC	0.579	Down-regulation
CAMK_CAMKL_BRSK_BRSK1_ST	Q8TDC3	BRSK1	Q8TDC3-2	BRSK1	T583	P588S	588	Missense	distal	5	no	0.653	0.588	EPSD	TCGA;GDSC;CCLE	0.579	Down-regulation
CAMK_CAMKL_BRSK_BRSK1_ST	Q8TDC3	BRSK1	Q8TDC3-2	BRSK1	T691	G685D	685	Missense	distal	-6	no	0.794	0.789	EPSD	TCGA;COSMIC	0.579	Down-regulation
CAMK_CAMKL_BRSK_BRSK1_ST	Q8TDC3	BRSK1	Q8TDC3-2	BRSK1	T691	S689F	689	Missense	proximal	-2	no	0.794	0.640	EPSD	TCGA;COSMIC	0.579	Down-regulation
CAMK_CAMKL_BRSK_BRSK1_ST	Q13131	PRKAA1	Q8TDC3-2	BRSK1	S254	Q261E	261	Missense	distal	7	no	0.764	0.768	EPSD	TCGA;COSMIC	0.579	Up-regulation
CAMK_CAMKL_BRSK_BRSK1_ST	P30291	WEE1	Q8TDC3-2	BRSK1	S203	V206F	206	Missense	distal	3	no	0.548	0.605	EPSD	TCGA;ICGC;COSMIC	0.579	Gain
CAMK_CAMKL_BRSK_BRSK1_ST	P30291	WEE1	Q8TDC3-2	BRSK1	S205	S204G	204	Missense	proximal	-1	no	0.797	0.863	EPSD	TCGA;ICGC;COSMIC	0.579	Up-regulation
CAMK_CAMKL_BRSK_BRSK1_ST	P30291	WEE1	Q8TDC3-2	BRSK1	S205	V206F	206	Missense	proximal	1	no	0.797	0.795	EPSD	TCGA;ICGC;COSMIC	0.579	Down-regulation
CAMK_CAMKL_BRSK_BRSK1_ST	P30291	WEE1	Q8TDC3-2	BRSK1	S571	H566R	566	Missense	distal	-5	no	0.650	0.698	EPSD	TCGA;ICGC;COSMIC	0.579	Up-regulation
CAMK_CAMKL_BRSK_BRSK1_ST	P23258	TUBG1	Q8TDC3-2	BRSK1	S131	V136L	136	Missense	distal	5	no	1.301	1.351	PhosphoSitePlus	TCGA;ICGC;COSMIC	0.579	Up-regulation
CAMK_CAMKL_BRSK_BRSK1_ST	P23258	TUBG1	Q8TDC3-2	BRSK1	S131	E133Q	133	Missense	proximal	2	no	1.301	1.297	PhosphoSitePlus	TCGA;ICGC;COSMIC	0.579	Down-regulation
CAMK_CAMKL_BRSK_BRSK1_ST	P23258	TUBG1	Q8TDC3-2	BRSK1	S306	R311C	311	Missense	distal	5	no	0.575	0.586	EPSD	TCGA;ICGC;COSMIC	0.579	Gain
CAMK_CAMKL_BRSK_BRSK1_ST	P23258	TUBG1	Q8TDC3-2	BRSK1	S336	R343C	343	Missense	distal	7	no	0.658	0.676	EPSD	TCGA;ICGC;COSMIC	0.579	Up-regulation
CAMK_CAMKL_BRSK_BRSK1_ST	P23258	TUBG1	Q8TDC3-2	BRSK1	S336	S336N	336	Missense	central	0	yes	0.658	0.000	EPSD	TCGA;ICGC;COSMIC	0.579	Loss
CAMK_CAMKL_BRSK_BRSK1_ST	P23258	TUBG1	Q8TDC3-2	BRSK1	S336	Q338H	338	Missense	proximal	2	no	0.658	0.659	EPSD	TCGA;ICGC;COSMIC	0.579	Up-regulation
CAMK_CAMKL_BRSK_BRSK1_ST	P23258	TUBG1	Q8TDC3-2	BRSK1	S385	E389K	389	Missense	distal	4	no	1.207	1.217	EPSD	TCGA;ICGC;COSMIC	0.579	Up-regulation
CAMK_CAMKL_BRSK_BRSK1_ST	P30305	CDC25B	Q8TDC3-2	BRSK1	S97	S103P	103	Missense	distal	6	no	0.556	0.653	EPSD	TCGA;COSMIC	0.579	Gain
CAMK_CAMKL_BRSK_BRSK1_ST	P30305	CDC25B	Q8TDC3-2	BRSK1	S115	G110C	110	Missense	distal	-5	no	0.711	0.699	EPSD	TCGA;ICGC;COSMIC	0.579	Down-regulation
CAMK_CAMKL_BRSK_BRSK1_ST	P30305	CDC25B	Q8TDC3-2	BRSK1	S115	G110D	110	Missense	distal	-5	no	0.711	0.690	EPSD	TCGA;COSMIC	0.579	Down-regulation
CAMK_CAMKL_BRSK_BRSK1_ST	P30305	CDC25B	Q8TDC3-2	BRSK1	S115	S115F	115	Missense	central	0	yes	0.711	0.000	EPSD	TCGA;COSMIC	0.579	Loss
CAMK_CAMKL_BRSK_BRSK1_ST	P30305	CDC25B	Q8TDC3-2	BRSK1	S323	R317Q	317	Missense	distal	-6	no	0.747	0.661	EPSD	TCGA;COSMIC	0.579	Down-regulation
CAMK_CAMKL_BRSK_BRSK1_ST	P30305	CDC25B	Q8TDC3-2	BRSK1	T355	E358K	358	Missense	distal	3	no	0.630	0.644	EPSD	TCGA;ICGC;COSMIC	0.579	Up-regulation
CAMK_CAMKL_BRSK_BRSK1_ST	P30305	CDC25B	Q8TDC3-2	BRSK1	T355	R352W	352	Missense	distal	-3	no	0.630	0.622	EPSD	TCGA;ICGC;COSMIC	0.579	Down-regulation
CAMK_CAMKL_BRSK_BRSK1_ST	P30305	CDC25B	Q8TDC3-2	BRSK1	S375	E380Q	380	Missense	distal	5	no	1.213	1.194	PhosphoSitePlus	TCGA;COSMIC	0.579	Down-regulation
CAMK_CAMKL_BRSK_BRSK1_ST	P30305	CDC25B	Q8TDC3-2	BRSK1	S375	S373T	373	Missense	proximal	-2	no	1.213	1.092	PhosphoSitePlus	TCGA;ICGC;COSMIC	0.579	Down-regulation
CAMK_CAMKL_BRSK_BRSK1_ST	P30305	CDC25B	Q8TDC3-2	BRSK1	S375	R369H	369	Missense	distal	-6	no	1.213	1.099	PhosphoSitePlus	TCGA;COSMIC	0.579	Down-regulation
CAMK_CAMKL_BRSK_BRSK1_ST	P30305	CDC25B	Q8TDC3-2	BRSK1	S397	R390Q	390	Missense	distal	-7	no	0.696	0.701	EPSD	TCGA;ICGC;COSMIC	0.579	Up-regulation
CAMK_CAMKL_BRSK_BRSK1_ST	P30307	CDC25C	Q8TDC3-2	BRSK1	S207	Q202E	202	Missense	distal	-5	no	0.747	0.815	EPSD	TCGA;ICGC;COSMIC	0.579	Up-regulation
CAMK_CAMKL_BRSK_BRSK1_ST	P30307	CDC25C	Q8TDC3-2	BRSK1	S207	R213H	213	Missense	distal	6	no	0.747	0.816	EPSD	TCGA;ICGC;COSMIC	0.579	Up-regulation
CAMK_CAMKL_BRSK_BRSK1_ST	P30307	CDC25C	Q8TDC3-2	BRSK1	S207	R213C	213	Missense	distal	6	no	0.747	0.756	EPSD	TCGA;ICGC;COSMIC	0.579	Up-regulation
CAMK_CAMKL_BRSK_BRSK1_ST	P30307	CDC25C	Q8TDC3-2	BRSK1	S207	S214F	214	Missense	distal	7	no	0.747	0.732	EPSD	TCGA;ICGC;COSMIC	0.579	Down-regulation
CAMK_CAMKL_BRSK_BRSK1_ST	P30307	CDC25C	Q8TDC3-2	BRSK1	S216	N222K	222	Missense	distal	6	no	1.279	1.253	PhosphoSitePlus	TCGA;ICGC;COSMIC	0.579	Down-regulation
CAMK_CAMKL_BRSK_BRSK1_ST	P30307	CDC25C	Q8TDC3-2	BRSK1	S216	P215Q	215	Missense	proximal	-1	no	1.279	1.237	PhosphoSitePlus	TCGA;ICGC;COSMIC	0.579	Down-regulation
CAMK_CAMKL_BRSK_BRSK1_ST	P30307	CDC25C	Q8TDC3-2	BRSK1	S216	R213H	213	Missense	distal	-3	no	1.279	1.276	PhosphoSitePlus	TCGA;ICGC;COSMIC	0.579	Down-regulation
CAMK_CAMKL_BRSK_BRSK1_ST	P30307	CDC25C	Q8TDC3-2	BRSK1	S216	R213C	213	Missense	distal	-3	no	1.279	1.271	PhosphoSitePlus	TCGA;ICGC;COSMIC	0.579	Down-regulation
CAMK_CAMKL_BRSK_BRSK1_ST	P30307	CDC25C	Q8TDC3-2	BRSK1	S216	S214F	214	Missense	proximal	-2	no	1.279	1.125	PhosphoSitePlus	TCGA;ICGC;COSMIC	0.579	Down-regulation
CAMK_CAMKL_BRSK_BRSK1_ST	P30307	CDC25C	Q8TDC3-2	BRSK1	S216	L221S	221	Missense	distal	5	no	1.279	1.180	PhosphoSitePlus	TCGA;ICGC;COSMIC	0.579	Down-regulation
TK_Ack_TNK2_Y	P10275	AR	Q07912	TNK2	Y19	Y19C	19	Missense	central	0	yes	0.000	0.000	EPSD	TCGA;ICGC	0.000	Loss
TK_Ack_TNK2_Y	P42768	WAS	Q07912	TNK2	Y212	Y212F	212	Missense	central	0	yes	0.000	0.000	EPSD	TCGA;ICGC;COSMIC	0.000	Loss
AGC_Akt_AKT3_ST	Q9UKV8	AGO2	Q9Y243	AKT3	S387	R384Q	384	Missense	distal	-3	no	8.468	6.263	PhosphoSitePlus	TCGA;ICGC;COSMIC	2.840	Down-regulation
AGC_Akt_AKT3_ST	Q9UKV8	AGO2	Q9Y243	AKT3	S387	V394I	394	Missense	distal	7	no	8.468	8.396	PhosphoSitePlus	TCGA;ICGC;COSMIC	2.840	Down-regulation
AGC_Akt_AKT3_ST	Q9UKV8	AGO2	Q9Y243	AKT3	S387	P392S	392	Missense	distal	5	no	8.468	8.550	PhosphoSitePlus	TCGA;ICGC;COSMIC	2.840	Up-regulation
AGC_Akt_AKT3_ST	Q9UKV8	AGO2	Q9Y243	AKT3	S798	P802R	802	Missense	distal	4	no	3.376	3.310	EPSD	TCGA;COSMIC	2.840	Down-regulation
AGC_Akt_AKT3_ST	Q9UKV8	AGO2	Q9Y243	AKT3	S798	R792C	792	Missense	distal	-6	no	3.376	3.305	EPSD	TCGA;COSMIC	2.840	Down-regulation
AGC_Akt_AKT3_ST	Q96ST2	IWS1	Q9Y243	AKT3	T42	G39R	39	Missense	distal	-3	no	1.390	4.045	EPSD	TCGA;ICGC;COSMIC	2.840	Gain
AGC_Akt_AKT3_ST	Q96ST2	IWS1	Q9Y243	AKT3	S415	A417V	417	Missense	proximal	2	no	3.508	3.660	EPSD	TCGA;COSMIC	2.840	Up-regulation
AGC_Akt_AKT3_ST	Q96ST2	IWS1	Q9Y243	AKT3	T435	K434N	434	Missense	proximal	-1	no	4.093	3.868	EPSD	TCGA;COSMIC	2.840	Down-regulation
AGC_Akt_AKT3_ST	Q96ST2	IWS1	Q9Y243	AKT3	T435	S438F	438	Missense	distal	3	no	4.093	3.976	EPSD	TCGA;COSMIC	2.840	Down-regulation
AGC_Akt_AKT3_ST	Q96ST2	IWS1	Q9Y243	AKT3	S440	K434N	434	Missense	distal	-6	no	3.679	3.651	EPSD	TCGA;COSMIC	2.840	Down-regulation
AGC_Akt_AKT3_ST	Q96ST2	IWS1	Q9Y243	AKT3	S440	S438F	438	Missense	proximal	-2	no	3.679	2.707	EPSD	TCGA;COSMIC	2.840	Loss
AGC_Akt_AKT3_ST	Q96ST2	IWS1	Q9Y243	AKT3	S513	D510N	510	Missense	distal	-3	no	3.554	3.162	EPSD	TCGA;ICGC;COSMIC	2.840	Down-regulation
AGC_Akt_AKT3_ST	Q96ST2	IWS1	Q9Y243	AKT3	S513	A508P	508	Missense	distal	-5	no	3.554	3.083	EPSD	TCGA;ICGC;COSMIC	2.840	Down-regulation
AGC_Akt_AKT3_ST	Q96ST2	IWS1	Q9Y243	AKT3	T589	V594A	594	Missense	distal	5	no	2.854	2.939	EPSD	TCGA;ICGC	2.840	Up-regulation
AGC_Akt_AKT3_ST	Q96ST2	IWS1	Q9Y243	AKT3	S720	R715Q	715	Missense	distal	-5	no	3.267	2.081	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC;GDSC;CCLE	2.840	Loss
AGC_Akt_AKT3_ST	Q96ST2	IWS1	Q9Y243	AKT3	T721	R715Q	715	Missense	distal	-6	no	2.900	2.872	PhosphoSitePlus;EPSD	TCGA;ICGC;COSMIC;GDSC;CCLE	2.840	Down-regulation
AGC_Akt_AKT3_ST	Q96ST2	IWS1	Q9Y243	AKT3	T796	D797N	797	Missense	proximal	1	no	3.579	3.588	EPSD	TCGA;ICGC;COSMIC	2.840	Up-regulation
AGC_Akt_AKT3_ST	O15119	TBX3	Q9Y243	AKT3	T121	K118R	118	Missense	distal	-3	no	1.742	3.584	EPSD	TCGA;ICGC;COSMIC	2.840	Gain
AGC_Akt_AKT3_ST	O15119	TBX3	Q9Y243	AKT3	T399	A392V	392	Missense	distal	-7	no	3.265	3.095	EPSD	TCGA;COSMIC	2.840	Down-regulation
AGC_Akt_AKT3_ST	O15119	TBX3	Q9Y243	AKT3	T399	A392T	392	Missense	distal	-7	no	3.265	3.267	EPSD	TCGA;COSMIC	2.840	Up-regulation
AGC_Akt_AKT3_ST	O15119	TBX3	Q9Y243	AKT3	T399	T398A	398	Missense	proximal	-1	no	3.265	3.408	EPSD	TCGA;COSMIC	2.840	Up-regulation
AGC_Akt_AKT3_ST	O15119	TBX3	Q9Y243	AKT3	S432	S432L	432	Missense	central	0	yes	3.279	0.000	EPSD	TCGA;COSMIC	2.840	Loss
AGC_Akt_AKT3_ST	O15119	TBX3	Q9Y243	AKT3	S443	R447G	447	Missense	distal	4	no	2.945	3.007	EPSD	TCGA;COSMIC	2.840	Up-regulation
AGC_Akt_AKT3_ST	O15119	TBX3	Q9Y243	AKT3	T462	P457L	457	Missense	distal	-5	no	3.316	3.400	EPSD	TCGA;COSMIC	2.840	Up-regulation
AGC_Akt_AKT3_ST	O15119	TBX3	Q9Y243	AKT3	S680	A685T	685	Missense	distal	5	no	3.050	2.938	EPSD	TCGA	2.840	Down-regulation
AGC_Akt_AKT3_ST	O15119	TBX3	Q9Y243	AKT3	S680	A676T	676	Missense	distal	-4	no	3.050	3.063	EPSD	TCGA;COSMIC	2.840	Up-regulation
AGC_Akt_AKT3_ST	O15119	TBX3	Q9Y243	AKT3	S690	R695H	695	Missense	distal	5	no	2.797	2.925	EPSD	TCGA;COSMIC;CCLE	2.840	Gain
AGC_Akt_AKT3_ST	O15119	TBX3	Q9Y243	AKT3	S690	G689C	689	Missense	proximal	-1	no	2.797	2.853	EPSD	TCGA;COSMIC	2.840	Gain
AGC_Akt_AKT3_ST	O15119	TBX3	Q9Y243	AKT3	T698	R695H	695	Missense	distal	-3	no	4.823	2.510	EPSD	TCGA;COSMIC;CCLE	2.840	Loss
AGC_Akt_AKT3_ST	O15119	TBX3	Q9Y243	AKT3	S700	R695H	695	Missense	distal	-5	no	2.878	1.746	EPSD	TCGA;COSMIC;CCLE	2.840	Loss
AGC_Akt_AKT3_ST	O15119	TBX3	Q9Y243	AKT3	S702	R695H	695	Missense	distal	-7	no	2.940	2.862	EPSD	TCGA;COSMIC;CCLE	2.840	Down-regulation
AGC_Akt_AKT3_ST	O15119	TBX3	Q9Y243	AKT3	S719	Q722L	722	Missense	distal	3	no	6.326	6.116	PhosphoSitePlus	TCGA;COSMIC	2.840	Down-regulation
AGC_Akt_AKT3_ST	O15119	TBX3	Q9Y243	AKT3	S719	S723I	723	Missense	distal	4	no	6.326	6.215	PhosphoSitePlus	TCGA;COSMIC	2.840	Down-regulation
AGC_Akt_AKT3_ST	O15119	TBX3	Q9Y243	AKT3	S719	S719G	719	Missense	central	0	yes	6.326	0.000	PhosphoSitePlus	TCGA;COSMIC	2.840	Loss
AGC_Akt_AKT3_ST	O15119	TBX3	Q9Y243	AKT3	S719	E720K	720	Missense	proximal	1	no	6.326	6.309	PhosphoSitePlus	TCGA;COSMIC	2.840	Down-regulation
AGC_Akt_AKT3_ST	O15119	TBX3	Q9Y243	AKT3	S729	G730S	730	Missense	proximal	1	no	3.665	3.632	EPSD	TCGA;COSMIC	2.840	Down-regulation
AGC_Akt_AKT3_ST	O15119	TBX3	Q9Y243	AKT3	S729	Q722L	722	Missense	distal	-7	no	3.665	3.631	EPSD	TCGA;COSMIC	2.840	Down-regulation
AGC_Akt_AKT3_ST	O15119	TBX3	Q9Y243	AKT3	S729	S723I	723	Missense	distal	-6	no	3.665	3.679	EPSD	TCGA;COSMIC	2.840	Up-regulation
AGC_Akt_AKT3_ST	O15119	TBX3	Q9Y243	AKT3	S740	R739C	739	Missense	proximal	-1	no	3.869	4.006	EPSD	TCGA	2.840	Up-regulation
AGC_Akt_AKT3_ST	O15119	TBX3	Q9Y243	AKT3	S742	R739C	739	Missense	distal	-3	no	5.611	3.198	EPSD	TCGA	2.840	Down-regulation
AGC_Akt_AKT3_ST	P15056	BRAF	Q9Y243	AKT3	S335	P341L	341	Missense	distal	6	no	3.225	3.203	EPSD	TCGA;ICGC;COSMIC	2.840	Down-regulation
AGC_Akt_AKT3_ST	P15056	BRAF	Q9Y243	AKT3	S339	P341L	341	Missense	proximal	2	no	2.797	2.942	EPSD	TCGA;ICGC;COSMIC	2.840	Gain
AGC_Akt_AKT3_ST	P15056	BRAF	Q9Y243	AKT3	S365	S364L	364	Missense	proximal	-1	no	9.586	8.620	PhosphoSitePlus;EPSD	TCGA;ICGC;COSMIC	2.840	Down-regulation
AGC_Akt_AKT3_ST	P15056	BRAF	Q9Y243	AKT3	S365	P367R	367	Missense	proximal	2	no	9.586	9.441	PhosphoSitePlus;EPSD	TCGA;ICGC;COSMIC	2.840	Down-regulation
AGC_Akt_AKT3_ST	P15056	BRAF	Q9Y243	AKT3	S365	P367S	367	Missense	proximal	2	no	9.586	9.260	PhosphoSitePlus;EPSD	TCGA;ICGC;COSMIC	2.840	Down-regulation
AGC_Akt_AKT3_ST	P15056	BRAF	Q9Y243	AKT3	T396	T401I	401	Missense	distal	5	no	2.686	2.921	EPSD	TCGA;ICGC;COSMIC	2.840	Gain
AGC_Akt_AKT3_ST	P15056	BRAF	Q9Y243	AKT3	S429	E433K	433	Missense	distal	4	no	8.364	8.404	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	2.840	Up-regulation
AGC_Akt_AKT3_ST	P15056	BRAF	Q9Y243	AKT3	S431	E433K	433	Missense	proximal	2	no	4.867	4.628	EPSD	TCGA;ICGC;COSMIC	2.840	Down-regulation
AGC_Akt_AKT3_ST	P15056	BRAF	Q9Y243	AKT3	T440	E433K	433	Missense	distal	-7	no	3.952	4.037	EPSD	TCGA;ICGC;COSMIC	2.840	Up-regulation
AGC_Akt_AKT3_ST	P15056	BRAF	Q9Y243	AKT3	S446	E451G	451	Missense	distal	5	no	4.270	4.272	EPSD	TCGA;ICGC;COSMIC	2.840	Up-regulation
AGC_Akt_AKT3_ST	P15056	BRAF	Q9Y243	AKT3	S446	D449N	449	Missense	distal	3	no	4.270	4.259	EPSD	TCGA;ICGC;COSMIC	2.840	Down-regulation
AGC_Akt_AKT3_ST	P15056	BRAF	Q9Y243	AKT3	S447	E451G	451	Missense	distal	4	no	5.637	5.609	EPSD	TCGA;ICGC;COSMIC	2.840	Down-regulation
AGC_Akt_AKT3_ST	P15056	BRAF	Q9Y243	AKT3	S447	D449N	449	Missense	proximal	2	no	5.637	5.938	EPSD	TCGA;ICGC;COSMIC	2.840	Up-regulation
AGC_Akt_AKT3_ST	P15056	BRAF	Q9Y243	AKT3	S465	S467L	467	Missense	proximal	2	no	2.664	3.135	EPSD	TCGA;ICGC;COSMIC	2.840	Gain
AGC_Akt_AKT3_ST	P15056	BRAF	Q9Y243	AKT3	S467	G466A	466	Missense	proximal	-1	no	2.337	3.118	EPSD	TCGA;ICGC;COSMIC	2.840	Gain
AGC_Akt_AKT3_ST	P15056	BRAF	Q9Y243	AKT3	T599	G596R	596	Missense	distal	-3	no	1.983	4.637	EPSD	TCGA;ICGC;COSMIC;GDSC;CCLE	2.840	Gain
AGC_Akt_AKT3_ST	P15056	BRAF	Q9Y243	AKT3	S729	L733F	733	Missense	distal	4	no	4.901	5.002	EPSD	TCGA;ICGC;COSMIC	2.840	Up-regulation
AGC_Akt_AKT3_ST	P15056	BRAF	Q9Y243	AKT3	S729	H725Y	725	Missense	distal	-4	no	4.901	4.906	EPSD	TCGA;ICGC;COSMIC	2.840	Up-regulation
AGC_Akt_AKT3_ST	P15056	BRAF	Q9Y243	AKT3	S729	R726C	726	Missense	distal	-3	no	4.901	2.489	EPSD	TCGA;ICGC;COSMIC;GDSC;CCLE	2.840	Loss
AGC_Akt_AKT3_ST	P15056	BRAF	Q9Y243	AKT3	S729	P731S	731	Missense	proximal	2	no	4.901	4.575	EPSD	TCGA;ICGC;COSMIC	2.840	Down-regulation
AGC_Akt_AKT3_ST	P15056	BRAF	Q9Y243	AKT3	S729	R735W	735	Missense	distal	6	no	4.901	4.823	EPSD	TCGA;ICGC;COSMIC	2.840	Down-regulation
AGC_Akt_AKT3_ST	P15056	BRAF	Q9Y243	AKT3	S729	N734S	734	Missense	distal	5	no	4.901	4.885	EPSD	TCGA;ICGC;COSMIC	2.840	Down-regulation
STE_STE11_MEKK1_MAP3K1_ST	O14733	MAP2K7	Q13233	MAP3K1	S265	D261N	261	Missense	distal	-4	no	2.426	2.164	EPSD	TCGA;COSMIC	2.285	Loss
STE_STE11_MEKK1_MAP3K1_ST	O14733	MAP2K7	Q13233	MAP3K1	S265	S265R	265	Missense	central	0	yes	2.426	0.000	EPSD	TCGA;COSMIC	2.285	Loss
STE_STE11_MEKK1_MAP3K1_ST	O14733	MAP2K7	Q13233	MAP3K1	S265	L259P	259	Missense	distal	-6	no	2.426	2.425	EPSD	TCGA;COSMIC	2.285	Down-regulation
STE_STE11_MEKK1_MAP3K1_ST	O14733	MAP2K7	Q13233	MAP3K1	S271	S265R	265	Missense	distal	-6	no	4.764	4.760	PhosphoSitePlus;EPSD	TCGA;COSMIC	2.285	Down-regulation
STE_STE11_MEKK1_MAP3K1_ST	O14733	MAP2K7	Q13233	MAP3K1	S271	R276Q	276	Missense	distal	5	no	4.764	4.774	PhosphoSitePlus;EPSD	TCGA;COSMIC	2.285	Up-regulation
STE_STE11_MEKK1_MAP3K1_ST	O14733	MAP2K7	Q13233	MAP3K1	S271	T275M	275	Missense	distal	4	no	4.764	4.792	PhosphoSitePlus;EPSD	TCGA;COSMIC;GDSC	2.285	Up-regulation
STE_STE11_MEKK1_MAP3K1_ST	O14733	MAP2K7	Q13233	MAP3K1	T275	G279S	279	Missense	distal	4	no	4.996	4.897	EPSD;PhosphoSitePlus	TCGA;COSMIC	2.285	Down-regulation
STE_STE11_MEKK1_MAP3K1_ST	O14733	MAP2K7	Q13233	MAP3K1	T275	R276Q	276	Missense	proximal	1	no	4.996	4.886	EPSD;PhosphoSitePlus	TCGA;COSMIC	2.285	Down-regulation
STE_STE11_MEKK1_MAP3K1_ST	O14733	MAP2K7	Q13233	MAP3K1	T275	T275M	275	Missense	central	0	yes	4.996	0.000	EPSD;PhosphoSitePlus	TCGA;COSMIC;GDSC	2.285	Loss
STE_STE11_MEKK1_MAP3K1_ST	O14733	MAP2K7	Q13233	MAP3K1	S407	P404L	404	Missense	distal	-3	no	1.919	2.290	EPSD	TCGA;COSMIC	2.285	Gain
STE_STE11_MEKK1_MAP3K1_ST	P46531	NOTCH1	Q13233	MAP3K1	S900	C893S	893	Missense	distal	-7	no	2.321	2.377	EPSD	TCGA;ICGC;COSMIC	2.285	Up-regulation
STE_STE11_MEKK1_MAP3K1_ST	P46531	NOTCH1	Q13233	MAP3K1	S1939	R1940H	1940	Missense	proximal	1	no	2.355	2.367	EPSD	TCGA;ICGC;COSMIC	2.285	Up-regulation
STE_STE11_MEKK1_MAP3K1_ST	P46531	NOTCH1	Q13233	MAP3K1	S1939	R1946H	1946	Missense	distal	7	no	2.355	2.357	EPSD	TCGA;ICGC;COSMIC	2.285	Up-regulation
STE_STE11_MEKK1_MAP3K1_ST	P46531	NOTCH1	Q13233	MAP3K1	S1939	D1942V	1942	Missense	distal	3	no	2.355	2.373	EPSD	TCGA;ICGC;COSMIC	2.285	Up-regulation
STE_STE11_MEKK1_MAP3K1_ST	P46531	NOTCH1	Q13233	MAP3K1	S1939	R1937H	1937	Missense	proximal	-2	no	2.355	2.232	EPSD	TCGA;ICGC;COSMIC	2.285	Loss
STE_STE11_MEKK1_MAP3K1_ST	P46531	NOTCH1	Q13233	MAP3K1	S1939	A1936T	1936	Missense	distal	-3	no	2.355	1.969	EPSD	TCGA;ICGC;COSMIC	2.285	Loss
STE_STE11_MEKK1_MAP3K1_ST	P46531	NOTCH1	Q13233	MAP3K1	S1939	L1934M	1934	Missense	distal	-5	no	2.355	2.087	EPSD	TCGA;ICGC;COSMIC	2.285	Loss
STE_STE11_MEKK1_MAP3K1_ST	P46531	NOTCH1	Q13233	MAP3K1	T1997	T1996M	1996	Missense	proximal	-1	no	2.767	2.763	EPSD	TCGA;ICGC;COSMIC;GDSC;CCLE	2.285	Down-regulation
STE_STE11_MEKK1_MAP3K1_ST	P46531	NOTCH1	Q13233	MAP3K1	T1997	H1993Y	1993	Missense	distal	-4	no	2.767	2.901	EPSD	TCGA;ICGC	2.285	Up-regulation
STE_STE11_MEKK1_MAP3K1_ST	P46531	NOTCH1	Q13233	MAP3K1	T1997	T1997M	1997	Missense	central	0	yes	2.767	0.000	EPSD	TCGA;ICGC;COSMIC	2.285	Loss
STE_STE11_MEKK1_MAP3K1_ST	P46531	NOTCH1	Q13233	MAP3K1	S2215	V2213L	2213	Missense	proximal	-2	no	2.244	2.301	EPSD	TCGA;ICGC;COSMIC	2.285	Gain
STE_STE11_MEKK1_MAP3K1_ST	P46531	NOTCH1	Q13233	MAP3K1	T2511	P2514T	2514	Missense	distal	3	no	4.557	4.577	PhosphoSitePlus	TCGA;ICGC;COSMIC	2.285	Up-regulation
STE_STE11_MEKK1_MAP3K1_ST	P46531	NOTCH1	Q13233	MAP3K1	S2516	S2521F	2521	Missense	distal	5	no	2.280	2.430	EPSD	TCGA;ICGC;COSMIC	2.285	Gain
STE_STE11_MEKK1_MAP3K1_ST	P46531	NOTCH1	Q13233	MAP3K1	S2516	S2523L	2523	Missense	distal	7	no	2.280	2.299	EPSD	TCGA;ICGC;COSMIC;GDSC;CCLE	2.285	Gain
STE_STE11_MEKK1_MAP3K1_ST	Q8NHW3	MAFA	Q13233	MAP3K1	S14	A9D	9	Missense	distal	-5	no	4.785	4.822	PhosphoSitePlus;EPSD	TCGA;ICGC;COSMIC	2.285	Up-regulation
STE_STE11_MEKK1_MAP3K1_ST	Q13158	FADD	Q13233	MAP3K1	S10	F4L	4	Missense	distal	-6	no	2.569	2.550	EPSD	TCGA	2.285	Down-regulation
STE_STE11_MEKK1_MAP3K1_ST	Q13158	FADD	Q13233	MAP3K1	S10	H9R	9	Missense	proximal	-1	no	2.569	2.564	EPSD	TCGA;ICGC;COSMIC	2.285	Down-regulation
STE_STE11_MEKK1_MAP3K1_ST	Q13158	FADD	Q13233	MAP3K1	S10	V6L	6	Missense	distal	-4	no	2.569	2.466	EPSD	TCGA;ICGC;COSMIC	2.285	Down-regulation
STE_STE11_MEKK1_MAP3K1_ST	Q13158	FADD	Q13233	MAP3K1	S10	L5P	5	Missense	distal	-5	no	2.569	2.246	EPSD	TCGA;ICGC	2.285	Loss
STE_STE11_MEKK1_MAP3K1_ST	Q13158	FADD	Q13233	MAP3K1	S10	S12W	12	Missense	proximal	2	no	2.569	1.195	EPSD	TCGA;ICGC;COSMIC	2.285	Loss
STE_STE11_MEKK1_MAP3K1_ST	Q13158	FADD	Q13233	MAP3K1	S12	H9R	9	Missense	distal	-3	no	1.942	2.579	EPSD	TCGA;ICGC;COSMIC	2.285	Gain
STE_STE11_MEKK1_MAP3K1_ST	Q13158	FADD	Q13233	MAP3K1	S14	E19K	19	Missense	distal	5	no	3.006	3.009	EPSD	TCGA;ICGC;COSMIC	2.285	Up-regulation
STE_STE11_MEKK1_MAP3K1_ST	Q13158	FADD	Q13233	MAP3K1	S14	H9R	9	Missense	distal	-5	no	3.006	3.051	EPSD	TCGA;ICGC;COSMIC	2.285	Up-regulation
STE_STE11_MEKK1_MAP3K1_ST	Q13158	FADD	Q13233	MAP3K1	S14	S12W	12	Missense	proximal	-2	no	3.006	2.673	EPSD	TCGA;ICGC;COSMIC	2.285	Down-regulation
STE_STE11_MEKK1_MAP3K1_ST	Q13158	FADD	Q13233	MAP3K1	S16	E19K	19	Missense	distal	3	no	2.805	2.811	EPSD	TCGA;ICGC;COSMIC	2.285	Up-regulation
STE_STE11_MEKK1_MAP3K1_ST	Q13158	FADD	Q13233	MAP3K1	S16	H9R	9	Missense	distal	-7	no	2.805	2.829	EPSD	TCGA;ICGC;COSMIC	2.285	Up-regulation
STE_STE11_MEKK1_MAP3K1_ST	Q13158	FADD	Q13233	MAP3K1	S16	S12W	12	Missense	distal	-4	no	2.805	2.172	EPSD	TCGA;ICGC;COSMIC	2.285	Loss
STE_STE11_MEKK1_MAP3K1_ST	Q13158	FADD	Q13233	MAP3K1	S18	E19K	19	Missense	proximal	1	no	2.915	3.063	EPSD	TCGA;ICGC;COSMIC	2.285	Up-regulation
STE_STE11_MEKK1_MAP3K1_ST	Q13158	FADD	Q13233	MAP3K1	S18	S12W	12	Missense	distal	-6	no	2.915	3.026	EPSD	TCGA;ICGC;COSMIC	2.285	Up-regulation
STE_STE11_MEKK1_MAP3K1_ST	Q13158	FADD	Q13233	MAP3K1	S18	F25L	25	Missense	distal	7	no	2.915	2.917	EPSD	TCGA;ICGC	2.285	Up-regulation
STE_STE11_MEKK1_MAP3K1_ST	Q13158	FADD	Q13233	MAP3K1	T138	R142W	142	Missense	distal	4	no	2.113	2.520	EPSD	TCGA;ICGC	2.285	Gain
STE_STE11_MEKK1_MAP3K1_ST	Q13158	FADD	Q13233	MAP3K1	S194	P195L	195	Missense	proximal	1	no	3.865	3.357	PhosphoSitePlus	TCGA;COSMIC	2.285	Down-regulation
STE_STE11_MEKK1_MAP3K1_ST	Q13158	FADD	Q13233	MAP3K1	S194	N188Y	188	Missense	distal	-6	no	3.865	3.730	PhosphoSitePlus	TCGA;ICGC;COSMIC	2.285	Down-regulation
Other_Bud32_TP53RK_ST	P04637	TP53	Q96S44	TP53RK	S46	D48N	48	Missense	proximal	2	no	2.106	2.169	EPSD	TCGA;ICGC;COSMIC;GDSC;CCLE	2.118	Gain
Other_Bud32_TP53RK_ST	P04637	TP53	Q96S44	TP53RK	S127	F134L	134	Missense	distal	7	no	1.774	2.167	EPSD	TCGA;ICGC;COSMIC;CCLE	2.118	Gain
TK_ALK_ALK_Y	P23246	SFPQ	Q9UM73	ALK	Y293	R287K	287	Missense	distal	-6	no	5.156	5.555	PhosphoSitePlus	TCGA	2.462	Up-regulation
TK_ALK_ALK_Y	P23246	SFPQ	Q9UM73	ALK	Y293	R296L	296	Missense	distal	3	no	5.156	5.175	PhosphoSitePlus	TCGA;ICGC;COSMIC	2.462	Up-regulation
TK_ALK_ALK_Y	P23246	SFPQ	Q9UM73	ALK	Y293	E290K	290	Missense	distal	-3	no	5.156	5.165	PhosphoSitePlus	TCGA;ICGC;COSMIC	2.462	Up-regulation
TK_ALK_ALK_Y	P31939	ATIC	Q9UM73	ALK	Y104	T109A	109	Missense	distal	5	no	5.385	5.390	PhosphoSitePlus	TCGA;ICGC;COSMIC	2.462	Up-regulation
TK_ALK_ALK_Y	P50552	VASP	Q9UM73	ALK	Y39	R35H	35	Missense	distal	-4	no	5.116	4.635	PhosphoSitePlus	TCGA;ICGC;COSMIC	2.462	Down-regulation
TK_ALK_ALK_Y	P50552	VASP	Q9UM73	ALK	Y39	A32V	32	Missense	distal	-7	no	5.116	5.008	PhosphoSitePlus	TCGA;ICGC;COSMIC	2.462	Down-regulation
TK_ALK_ALK_Y	P50552	VASP	Q9UM73	ALK	Y39	Q37K	37	Missense	proximal	-2	no	5.116	5.061	PhosphoSitePlus	TCGA;ICGC;COSMIC	2.462	Down-regulation
TK_ALK_ALK_Y	P50552	VASP	Q9UM73	ALK	Y39	A44T	44	Missense	distal	5	no	5.116	5.111	PhosphoSitePlus	TCGA;ICGC;COSMIC	2.462	Down-regulation
TK_ALK_ALK_Y	P62993	GRB2	Q9UM73	ALK	Y160	Q156R	156	Missense	distal	-4	no	5.249	5.440	PhosphoSitePlus	TCGA;ICGC;COSMIC	2.462	Up-regulation
TK_ALK_ALK_Y	P62993	GRB2	Q9UM73	ALK	Y160	V154L	154	Missense	distal	-6	no	5.249	5.233	PhosphoSitePlus	TCGA;ICGC;COSMIC	2.462	Down-regulation
TK_ALK_ALK_Y	P62993	GRB2	Q9UM73	ALK	Y160	V161F	161	Missense	proximal	1	no	5.249	5.392	PhosphoSitePlus	TCGA;ICGC;COSMIC	2.462	Up-regulation
AGC_RSK_MSK_RPS6KA5_ST	P16220	CREB1	O75582	RPS6KA5	S108	S103A	103	Missense	distal	-5	no	1.753	1.764	EPSD	TCGA;COSMIC	1.456	Up-regulation
AGC_RSK_MSK_RPS6KA5_ST	P16220	CREB1	O75582	RPS6KA5	S108	Q112H	112	Missense	distal	4	no	1.753	1.751	EPSD	TCGA;COSMIC	1.456	Down-regulation
AGC_RSK_MSK_RPS6KA5_ST	P16220	CREB1	O75582	RPS6KA5	S114	D116G	116	Missense	proximal	2	no	1.594	1.598	EPSD	TCGA;COSMIC	1.456	Up-regulation
AGC_RSK_MSK_RPS6KA5_ST	P16220	CREB1	O75582	RPS6KA5	S114	Q112H	112	Missense	proximal	-2	no	1.594	1.604	EPSD	TCGA;COSMIC	1.456	Up-regulation
AGC_RSK_MSK_RPS6KA5_ST	O75582	RPS6KA5	O75582	RPS6KA5	S212	A210V	210	Missense	proximal	-2	no	2.933	2.195	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	1.456	Down-regulation
AGC_RSK_MSK_RPS6KA5_ST	O75582	RPS6KA5	O75582	RPS6KA5	S212	E208Q	208	Missense	distal	-4	no	2.933	2.911	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	1.456	Down-regulation
AGC_RSK_MSK_RPS6KA5_ST	O75582	RPS6KA5	O75582	RPS6KA5	S381	Y375F	375	Missense	distal	-6	no	1.719	1.725	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	1.456	Up-regulation
AGC_RSK_MSK_RPS6KA5_ST	O75582	RPS6KA5	O75582	RPS6KA5	S381	S376C	376	Missense	distal	-5	no	1.719	1.716	EPSD;PhosphoSitePlus	TCGA;ICGC	1.456	Down-regulation
AGC_RSK_MSK_RPS6KA5_ST	O75582	RPS6KA5	O75582	RPS6KA5	S381	L383I	383	Missense	proximal	2	no	1.719	1.720	EPSD;PhosphoSitePlus	TCGA;ICGC	1.456	Up-regulation
AGC_RSK_MSK_RPS6KA5_ST	O75582	RPS6KA5	O75582	RPS6KA5	S381	R386C	386	Missense	distal	5	no	1.719	1.701	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	1.456	Down-regulation
AGC_RSK_MSK_RPS6KA5_ST	O75582	RPS6KA5	O75582	RPS6KA5	S436	G433R	433	Missense	distal	-3	no	0.764	1.758	EPSD	TCGA	1.456	Gain
AGC_RSK_MSK_RPS6KA5_ST	O75582	RPS6KA5	O75582	RPS6KA5	S438	S436R	436	Missense	proximal	-2	no	1.297	2.701	EPSD	TCGA;ICGC	1.456	Gain
AGC_RSK_MSK_RPS6KA5_ST	O75582	RPS6KA5	O75582	RPS6KA5	S750	T751S	751	Missense	proximal	1	no	1.561	1.565	EPSD;PhosphoSitePlus	TCGA;COSMIC	1.456	Up-regulation
AGC_RSK_MSK_RPS6KA5_ST	O75582	RPS6KA5	O75582	RPS6KA5	S750	S750I	750	Missense	central	0	yes	1.561	0.000	EPSD;PhosphoSitePlus	TCGA;COSMIC	1.456	Loss
AGC_RSK_MSK_RPS6KA5_ST	O75582	RPS6KA5	O75582	RPS6KA5	S758	T751S	751	Missense	distal	-7	no	2.440	2.417	EPSD;PhosphoSitePlus	TCGA;COSMIC	1.456	Down-regulation
AGC_RSK_MSK_RPS6KA5_ST	P10276	RARA	O75582	RPS6KA5	S219	R217C	217	Missense	proximal	-2	no	2.659	0.978	EPSD	TCGA;COSMIC	1.456	Loss
AGC_RSK_MSK_RPS6KA5_ST	P10276	RARA	O75582	RPS6KA5	S219	R217H	217	Missense	proximal	-2	no	2.659	1.080	EPSD	TCGA;COSMIC	1.456	Loss
AGC_RSK_MSK_RPS6KA5_ST	P10276	RARA	O75582	RPS6KA5	S219	R217S	217	Missense	proximal	-2	no	2.659	1.255	EPSD	TCGA;COSMIC	1.456	Loss
AGC_RSK_MSK_RPS6KA5_ST	P10276	RARA	O75582	RPS6KA5	S219	S214L	214	Missense	distal	-5	no	2.659	2.653	EPSD	TCGA;COSMIC	1.456	Down-regulation
AGC_RSK_MSK_RPS6KA5_ST	P10276	RARA	O75582	RPS6KA5	S219	R217P	217	Missense	proximal	-2	no	2.659	0.792	EPSD	TCGA;COSMIC	1.456	Loss
AGC_RSK_MSK_RPS6KA5_ST	P10276	RARA	O75582	RPS6KA5	S219	R217G	217	Missense	proximal	-2	no	2.659	0.929	EPSD	TCGA;COSMIC	1.456	Loss
AGC_RSK_MSK_RPS6KA5_ST	P10276	RARA	O75582	RPS6KA5	S369	V363L	363	Missense	distal	-6	no	3.638	3.625	PhosphoSitePlus	TCGA;COSMIC	1.456	Down-regulation
AGC_RSK_MSK_RPS6KA5_ST	P10276	RARA	O75582	RPS6KA5	S369	S369I	369	Missense	central	0	yes	3.638	0.000	PhosphoSitePlus	TCGA	1.456	Loss
AGC_RSK_MSK_RPS6KA5_ST	P54253	ATXN1	O75582	RPS6KA5	S25	E27K	27	Missense	proximal	2	no	1.538	1.564	EPSD	TCGA;ICGC;COSMIC	1.456	Up-regulation
AGC_RSK_MSK_RPS6KA5_ST	P54253	ATXN1	O75582	RPS6KA5	S26	E27K	27	Missense	proximal	1	no	2.709	2.697	EPSD	TCGA;ICGC;COSMIC	1.456	Down-regulation
AGC_RSK_MSK_RPS6KA5_ST	P54253	ATXN1	O75582	RPS6KA5	S262	P264L	264	Missense	proximal	2	no	1.676	1.679	EPSD	TCGA;ICGC;COSMIC	1.456	Up-regulation
AGC_RSK_MSK_RPS6KA5_ST	P54253	ATXN1	O75582	RPS6KA5	S262	P267L	267	Missense	distal	5	no	1.676	1.678	EPSD	TCGA;ICGC;COSMIC	1.456	Up-regulation
AGC_RSK_MSK_RPS6KA5_ST	P54253	ATXN1	O75582	RPS6KA5	S262	V268I	268	Missense	distal	6	no	1.676	1.674	EPSD	TCGA;ICGC;COSMIC;CCLE	1.456	Down-regulation
AGC_RSK_MSK_RPS6KA5_ST	P54253	ATXN1	O75582	RPS6KA5	S312	E310K	310	Missense	proximal	-2	no	1.272	1.783	EPSD	TCGA;ICGC;COSMIC	1.456	Gain
AGC_RSK_MSK_RPS6KA5_ST	P54253	ATXN1	O75582	RPS6KA5	S339	P337R	337	Missense	proximal	-2	no	0.913	2.780	EPSD	TCGA;ICGC;COSMIC	1.456	Gain
AGC_RSK_MSK_RPS6KA5_ST	P54253	ATXN1	O75582	RPS6KA5	S677	P672L	672	Missense	distal	-5	no	1.577	1.579	EPSD	TCGA;ICGC;COSMIC	1.456	Up-regulation
AGC_RSK_MSK_RPS6KA5_ST	P54253	ATXN1	O75582	RPS6KA5	S677	S684L	684	Missense	distal	7	no	1.577	1.608	EPSD	TCGA;ICGC	1.456	Up-regulation
AGC_RSK_MSK_RPS6KA5_ST	P54253	ATXN1	O75582	RPS6KA5	S775	A776V	776	Missense	proximal	1	no	3.524	3.537	PhosphoSitePlus	TCGA;ICGC;COSMIC	1.456	Up-regulation
AGC_RSK_MSK_RPS6KA5_ST	P54253	ATXN1	O75582	RPS6KA5	S775	K771E	771	Missense	distal	-4	no	3.524	3.578	PhosphoSitePlus	TCGA;ICGC;COSMIC;GDSC;CCLE	1.456	Up-regulation
AGC_RSK_MSK_RPS6KA5_ST	P18846	ATF1	O75582	RPS6KA5	S47	D46N	46	Missense	proximal	-1	no	1.541	1.547	EPSD	TCGA;ICGC;COSMIC	1.456	Up-regulation
AGC_RSK_MSK_RPS6KA5_ST	P18846	ATF1	O75582	RPS6KA5	S47	Q42H	42	Missense	distal	-5	no	1.541	1.540	EPSD	TCGA;ICGC;COSMIC	1.456	Down-regulation
AGC_RSK_MSK_RPS6KA5_ST	P18846	ATF1	O75582	RPS6KA5	S189	R182Q	182	Missense	distal	-7	no	1.428	1.493	EPSD	TCGA;COSMIC	1.456	Gain
AGC_RSK_MSK_RPS6KA5_ST	Q04206	RELA	O75582	RPS6KA5	S45	E39K	39	Missense	distal	-6	no	1.469	1.440	EPSD	TCGA;ICGC;COSMIC	1.456	Loss
AGC_RSK_MSK_RPS6KA5_ST	Q04206	RELA	O75582	RPS6KA5	S45	E49K	49	Missense	distal	4	no	1.469	1.499	EPSD	TCGA;ICGC;COSMIC	1.456	Up-regulation
AGC_RSK_MSK_RPS6KA5_ST	Q04206	RELA	O75582	RPS6KA5	S45	G44V	44	Missense	proximal	-1	no	1.469	1.464	EPSD	TCGA;ICGC;COSMIC	1.456	Down-regulation
AGC_RSK_MSK_RPS6KA5_ST	Q04206	RELA	O75582	RPS6KA5	S203	D210Y	210	Missense	distal	7	no	2.479	2.474	EPSD	TCGA;ICGC;COSMIC	1.456	Down-regulation
AGC_RSK_MSK_RPS6KA5_ST	Q04206	RELA	O75582	RPS6KA5	S203	G208S	208	Missense	distal	5	no	2.479	2.484	EPSD	TCGA;ICGC;COSMIC;GDSC;CCLE	1.456	Up-regulation
AGC_RSK_MSK_RPS6KA5_ST	Q04206	RELA	O75582	RPS6KA5	S269	S276F	276	Missense	distal	7	no	2.579	2.611	EPSD	TCGA;ICGC;COSMIC	1.456	Up-regulation
AGC_RSK_MSK_RPS6KA5_ST	Q04206	RELA	O75582	RPS6KA5	S269	R274W	274	Missense	distal	5	no	2.579	2.560	EPSD	TCGA;ICGC	1.456	Down-regulation
AGC_RSK_MSK_RPS6KA5_ST	Q04206	RELA	O75582	RPS6KA5	S269	R273W	273	Missense	distal	4	no	2.579	2.546	EPSD	TCGA;ICGC	1.456	Down-regulation
AGC_RSK_MSK_RPS6KA5_ST	Q04206	RELA	O75582	RPS6KA5	S276	S276F	276	Missense	central	0	yes	4.060	0.000	PhosphoSitePlus	TCGA;ICGC;COSMIC	1.456	Loss
AGC_RSK_MSK_RPS6KA5_ST	Q04206	RELA	O75582	RPS6KA5	S276	R274W	274	Missense	proximal	-2	no	4.060	2.366	PhosphoSitePlus	TCGA;ICGC	1.456	Down-regulation
AGC_RSK_MSK_RPS6KA5_ST	Q04206	RELA	O75582	RPS6KA5	S276	R273W	273	Missense	distal	-3	no	4.060	3.078	PhosphoSitePlus	TCGA;ICGC	1.456	Down-regulation
AGC_RSK_MSK_RPS6KA5_ST	Q04206	RELA	O75582	RPS6KA5	S281	S276F	276	Missense	distal	-5	no	2.260	2.252	EPSD	TCGA;ICGC;COSMIC	1.456	Down-regulation
AGC_RSK_MSK_RPS6KA5_ST	Q04206	RELA	O75582	RPS6KA5	S281	R274W	274	Missense	distal	-7	no	2.260	2.331	EPSD	TCGA;ICGC	1.456	Up-regulation
AGC_RSK_MSK_RPS6KA5_ST	Q04206	RELA	O75582	RPS6KA5	S311	T308A	308	Missense	distal	-3	no	1.170	1.560	EPSD	TCGA;ICGC;COSMIC	1.456	Gain
AGC_RSK_MSK_RPS6KA5_ST	Q04206	RELA	O75582	RPS6KA5	S316	F309L	309	Missense	distal	-7	no	1.662	1.658	EPSD	TCGA;ICGC;COSMIC	1.456	Down-regulation
AGC_RSK_MSK_RPS6KA5_ST	Q04206	RELA	O75582	RPS6KA5	S316	G320E	320	Missense	distal	4	no	1.662	1.663	EPSD	TCGA;ICGC;COSMIC	1.456	Up-regulation
AGC_RSK_MSK_RPS6KA5_ST	Q04206	RELA	O75582	RPS6KA5	S338	A339T	339	Missense	proximal	1	no	2.724	2.737	EPSD	TCGA;ICGC;COSMIC;CCLE	1.456	Up-regulation
AGC_RSK_MSK_RPS6KA5_ST	Q04206	RELA	O75582	RPS6KA5	S338	A332D	332	Missense	distal	-6	no	2.724	2.764	EPSD	TCGA;ICGC	1.456	Up-regulation
AGC_RSK_MSK_RPS6KA5_ST	Q9H4A3	WNK1	O75582	RPS6KA5	S29	A22S	22	Missense	distal	-7	no	1.542	1.566	EPSD	TCGA;ICGC;COSMIC	1.456	Up-regulation
AGC_RSK_MSK_RPS6KA5_ST	Q9H4A3	WNK1	O75582	RPS6KA5	T60	D62G	62	Missense	proximal	2	no	2.066	2.071	PhosphoSitePlus	TCGA;ICGC;COSMIC	1.456	Up-regulation
AGC_RSK_MSK_RPS6KA5_ST	Q9H4A3	WNK1	O75582	RPS6KA5	S167	T160N	160	Missense	distal	-7	no	1.931	1.914	EPSD	TCGA;ICGC;COSMIC	1.456	Down-regulation
AGC_RSK_MSK_RPS6KA5_ST	Q9H4A3	WNK1	O75582	RPS6KA5	S167	V172E	172	Missense	distal	5	no	1.931	1.933	EPSD	TCGA;ICGC;COSMIC	1.456	Up-regulation
AGC_RSK_MSK_RPS6KA5_ST	Q9H4A3	WNK1	O75582	RPS6KA5	S183	R182T	182	Missense	proximal	-1	no	1.825	1.781	EPSD	TCGA;ICGC;COSMIC	1.456	Down-regulation
AGC_RSK_MSK_RPS6KA5_ST	Q9H4A3	WNK1	O75582	RPS6KA5	S185	R182T	182	Missense	distal	-3	no	2.067	1.001	EPSD	TCGA;ICGC;COSMIC	1.456	Loss
AGC_RSK_MSK_RPS6KA5_ST	Q9H4A3	WNK1	O75582	RPS6KA5	S378	L374Q	374	Missense	distal	-4	no	2.926	2.910	EPSD	TCGA;ICGC;COSMIC	1.456	Down-regulation
AGC_RSK_MSK_RPS6KA5_ST	Q9H4A3	WNK1	O75582	RPS6KA5	S378	R376W	376	Missense	proximal	-2	no	2.926	1.231	EPSD	TCGA;ICGC	1.456	Loss
AGC_RSK_MSK_RPS6KA5_ST	Q9H4A3	WNK1	O75582	RPS6KA5	T436	R433L	433	Missense	distal	-3	no	1.714	0.668	EPSD	TCGA;ICGC;COSMIC	1.456	Loss
AGC_RSK_MSK_RPS6KA5_ST	Q9H4A3	WNK1	O75582	RPS6KA5	T436	R434H	434	Missense	proximal	-2	no	1.714	0.136	EPSD	TCGA;ICGC;COSMIC	1.456	Loss
AGC_RSK_MSK_RPS6KA5_ST	Q9H4A3	WNK1	O75582	RPS6KA5	S437	R433L	433	Missense	distal	-4	no	1.497	1.615	EPSD	TCGA;ICGC;COSMIC	1.456	Up-regulation
AGC_RSK_MSK_RPS6KA5_ST	Q9H4A3	WNK1	O75582	RPS6KA5	S437	R434H	434	Missense	distal	-3	no	1.497	0.583	EPSD	TCGA;ICGC;COSMIC	1.456	Loss
AGC_RSK_MSK_RPS6KA5_ST	Q9H4A3	WNK1	O75582	RPS6KA5	S469	L473F	473	Missense	distal	4	no	2.679	2.669	EPSD	TCGA	1.456	Down-regulation
AGC_RSK_MSK_RPS6KA5_ST	Q9H4A3	WNK1	O75582	RPS6KA5	S469	L473I	473	Missense	distal	4	no	2.679	2.675	EPSD	TCGA;ICGC	1.456	Down-regulation
AGC_RSK_MSK_RPS6KA5_ST	Q9H4A3	WNK1	O75582	RPS6KA5	S563	I558M	558	Missense	distal	-5	no	2.710	2.713	EPSD	TCGA;COSMIC	1.456	Up-regulation
AGC_RSK_MSK_RPS6KA5_ST	Q9H4A3	WNK1	O75582	RPS6KA5	S563	K566N	566	Missense	distal	3	no	2.710	2.681	EPSD	TCGA;ICGC;COSMIC	1.456	Down-regulation
AGC_RSK_MSK_RPS6KA5_ST	Q9H4A3	WNK1	O75582	RPS6KA5	S1105	R1109L	1109	Missense	distal	4	no	2.890	2.859	EPSD	TCGA;COSMIC	1.456	Down-regulation
AGC_RSK_MSK_RPS6KA5_ST	Q9H4A3	WNK1	O75582	RPS6KA5	S1105	R1109H	1109	Missense	distal	4	no	2.890	2.862	EPSD	TCGA	1.456	Down-regulation
AGC_RSK_MSK_RPS6KA5_ST	Q9H4A3	WNK1	O75582	RPS6KA5	S1105	R1100W	1100	Missense	distal	-5	no	2.890	2.850	EPSD	TCGA;COSMIC	1.456	Down-regulation
AGC_RSK_MSK_RPS6KA5_ST	Q9H4A3	WNK1	O75582	RPS6KA5	S1105	R1111Q	1111	Missense	distal	6	no	2.890	2.895	EPSD	TCGA	1.456	Up-regulation
AGC_RSK_MSK_RPS6KA5_ST	Q9H4A3	WNK1	O75582	RPS6KA5	S1110	R1109L	1109	Missense	proximal	-1	no	2.208	2.175	EPSD	TCGA;COSMIC	1.456	Down-regulation
AGC_RSK_MSK_RPS6KA5_ST	Q9H4A3	WNK1	O75582	RPS6KA5	S1110	R1109H	1109	Missense	proximal	-1	no	2.208	2.178	EPSD	TCGA	1.456	Down-regulation
AGC_RSK_MSK_RPS6KA5_ST	Q9H4A3	WNK1	O75582	RPS6KA5	S1110	R1111Q	1111	Missense	proximal	1	no	2.208	2.224	EPSD	TCGA	1.456	Up-regulation
AGC_RSK_MSK_RPS6KA5_ST	Q9H4A3	WNK1	O75582	RPS6KA5	S1285	S1289N	1289	Missense	distal	4	no	1.504	1.496	EPSD	TCGA	1.456	Down-regulation
AGC_RSK_MSK_RPS6KA5_ST	Q9H4A3	WNK1	O75582	RPS6KA5	S1297	H1296D	1296	Missense	proximal	-1	no	1.548	1.537	EPSD	TCGA;COSMIC	1.456	Down-regulation
AGC_RSK_MSK_RPS6KA5_ST	Q9H4A3	WNK1	O75582	RPS6KA5	S1297	S1300C	1300	Missense	distal	3	no	1.548	1.559	EPSD	TCGA;COSMIC	1.456	Up-regulation
AGC_RSK_MSK_RPS6KA5_ST	Q9H4A3	WNK1	O75582	RPS6KA5	S1297	A1298V	1298	Missense	proximal	1	no	1.548	1.560	EPSD	TCGA	1.456	Up-regulation
AGC_RSK_MSK_RPS6KA5_ST	Q9H4A3	WNK1	O75582	RPS6KA5	S1297	S1300P	1300	Missense	distal	3	no	1.548	1.546	EPSD	TCGA;COSMIC	1.456	Down-regulation
AGC_RSK_MSK_RPS6KA5_ST	Q9H4A3	WNK1	O75582	RPS6KA5	S1300	H1296D	1296	Missense	distal	-4	no	1.518	1.549	EPSD	TCGA;COSMIC	1.456	Up-regulation
AGC_RSK_MSK_RPS6KA5_ST	Q9H4A3	WNK1	O75582	RPS6KA5	S1300	L1303I	1303	Missense	distal	3	no	1.518	1.514	EPSD	TCGA;COSMIC	1.456	Down-regulation
AGC_RSK_MSK_RPS6KA5_ST	Q9H4A3	WNK1	O75582	RPS6KA5	S1300	S1300C	1300	Missense	central	0	yes	1.518	0.000	EPSD	TCGA;COSMIC	1.456	Loss
AGC_RSK_MSK_RPS6KA5_ST	Q9H4A3	WNK1	O75582	RPS6KA5	S1300	A1298V	1298	Missense	proximal	-2	no	1.518	0.780	EPSD	TCGA	1.456	Loss
AGC_RSK_MSK_RPS6KA5_ST	Q9H4A3	WNK1	O75582	RPS6KA5	S1300	S1300P	1300	Missense	central	0	yes	1.518	0.000	EPSD	TCGA;COSMIC	1.456	Loss
AGC_RSK_MSK_RPS6KA5_ST	Q9H4A3	WNK1	O75582	RPS6KA5	S1302	A1298V	1298	Missense	distal	-4	no	1.424	1.502	EPSD	TCGA	1.456	Gain
AGC_RSK_MSK_RPS6KA5_ST	Q9H4A3	WNK1	O75582	RPS6KA5	S1308	L1303I	1303	Missense	distal	-5	no	1.653	1.652	EPSD	TCGA;COSMIC	1.456	Down-regulation
AGC_RSK_MSK_RPS6KA5_ST	Q9H4A3	WNK1	O75582	RPS6KA5	S1308	R1312C	1312	Missense	distal	4	no	1.653	1.620	EPSD	TCGA;COSMIC	1.456	Down-regulation
AGC_RSK_MSK_RPS6KA5_ST	Q9H4A3	WNK1	O75582	RPS6KA5	S1528	H1534D	1534	Missense	distal	6	no	1.518	1.520	EPSD	TCGA;COSMIC	1.456	Up-regulation
AGC_RSK_MSK_RPS6KA5_ST	Q9H4A3	WNK1	O75582	RPS6KA5	S1528	K1531N	1531	Missense	distal	3	no	1.518	1.488	EPSD	TCGA;COSMIC	1.456	Down-regulation
AGC_RSK_MSK_RPS6KA5_ST	Q9H4A3	WNK1	O75582	RPS6KA5	S1528	L1529V	1529	Missense	proximal	1	no	1.518	1.521	EPSD	TCGA;COSMIC	1.456	Up-regulation
AGC_RSK_MSK_RPS6KA5_ST	Q9H4A3	WNK1	O75582	RPS6KA5	S1528	V1523A	1523	Missense	distal	-5	no	1.518	1.539	EPSD	TCGA;COSMIC	1.456	Up-regulation
AGC_RSK_MSK_RPS6KA5_ST	Q9H4A3	WNK1	O75582	RPS6KA5	S1528	A1526T	1526	Missense	proximal	-2	no	1.518	0.799	EPSD	TCGA;ICGC;COSMIC	1.456	Loss
AGC_RSK_MSK_RPS6KA5_ST	Q9H4A3	WNK1	O75582	RPS6KA5	S1838	Q1839P	1839	Missense	proximal	1	no	1.567	1.573	EPSD	TCGA;COSMIC	1.456	Up-regulation
AGC_RSK_MSK_RPS6KA5_ST	Q9H4A3	WNK1	O75582	RPS6KA5	S1959	F1958L	1958	Missense	proximal	-1	no	2.597	2.604	EPSD	TCGA;COSMIC	1.456	Up-regulation
AGC_RSK_MSK_RPS6KA5_ST	Q9H4A3	WNK1	O75582	RPS6KA5	S1959	R1957C	1957	Missense	proximal	-2	no	2.597	0.917	EPSD	TCGA;COSMIC	1.456	Loss
AGC_RSK_MSK_RPS6KA5_ST	Q9H4A3	WNK1	O75582	RPS6KA5	S1959	R1957H	1957	Missense	proximal	-2	no	2.597	1.019	EPSD	TCGA;COSMIC	1.456	Loss
AGC_RSK_MSK_RPS6KA5_ST	Q9H4A3	WNK1	O75582	RPS6KA5	T2128	S2135F	2135	Missense	distal	7	no	2.040	2.072	EPSD	TCGA	1.456	Up-regulation
AGC_RSK_MSK_RPS6KA5_ST	Q9H4A3	WNK1	O75582	RPS6KA5	S2136	S2135F	2135	Missense	proximal	-1	no	1.576	1.567	EPSD	TCGA	1.456	Down-regulation
AGC_RSK_MSK_RPS6KA5_ST	Q9H4A3	WNK1	O75582	RPS6KA5	S2139	S2145N	2145	Missense	distal	6	no	2.716	2.722	EPSD	TCGA;COSMIC	1.456	Up-regulation
AGC_RSK_MSK_RPS6KA5_ST	Q9H4A3	WNK1	O75582	RPS6KA5	S2139	S2135F	2135	Missense	distal	-4	no	2.716	2.753	EPSD	TCGA	1.456	Up-regulation
AGC_RSK_MSK_RPS6KA5_ST	Q9H4A3	WNK1	O75582	RPS6KA5	S2140	S2145N	2145	Missense	distal	5	no	2.045	2.037	EPSD	TCGA;COSMIC	1.456	Down-regulation
AGC_RSK_MSK_RPS6KA5_ST	Q9H4A3	WNK1	O75582	RPS6KA5	S2140	S2135F	2135	Missense	distal	-5	no	2.045	2.037	EPSD	TCGA	1.456	Down-regulation
AGC_RSK_MSK_RPS6KA5_ST	Q9H4A3	WNK1	O75582	RPS6KA5	S2270	S2265L	2265	Missense	distal	-5	no	3.662	3.656	EPSD	TCGA;COSMIC	1.456	Down-regulation
AGC_RSK_MSK_RPS6KA5_ST	Q9H4A3	WNK1	O75582	RPS6KA5	S2372	S2370F	2370	Missense	proximal	-2	no	1.480	1.076	EPSD	TCGA;COSMIC	1.456	Loss
AGC_RSK_MSK_RPS6KA5_ST	P11831	SRF	O75582	RPS6KA5	S237	E242K	242	Missense	distal	5	no	2.866	2.875	EPSD	TCGA;COSMIC	1.456	Up-regulation
AGC_RSK_MSK_RPS6KA5_ST	P11831	SRF	O75582	RPS6KA5	S237	T244R	244	Missense	distal	7	no	2.866	2.801	EPSD	TCGA;COSMIC	1.456	Down-regulation
AGC_RSK_MSK_RPS6KA5_ST	P11831	SRF	O75582	RPS6KA5	S311	V310I	310	Missense	proximal	-1	no	1.567	1.577	EPSD	TCGA;ICGC;COSMIC	1.456	Up-regulation
AGC_RSK_MSK_RPS6KA5_ST	P11831	SRF	O75582	RPS6KA5	S311	A308V	308	Missense	distal	-3	no	1.567	1.148	EPSD	TCGA;ICGC;COSMIC	1.456	Loss
AGC_RSK_MSK_RPS6KA5_ST	P11831	SRF	O75582	RPS6KA5	S316	V310I	310	Missense	distal	-6	no	1.748	1.737	EPSD	TCGA;ICGC;COSMIC	1.456	Down-regulation
AGC_RSK_MSK_RPS6KA5_ST	P11831	SRF	O75582	RPS6KA5	S446	V443A	443	Missense	distal	-3	no	1.066	1.486	EPSD	TCGA;COSMIC	1.456	Gain
AGC_RSK_MSK_RPS6KA5_ST	P19419	ELK1	O75582	RPS6KA5	S198	S196R	196	Missense	proximal	-2	no	1.152	2.555	EPSD	TCGA;ICGC;COSMIC	1.456	Gain
AGC_RSK_MSK_RPS6KA5_ST	P19419	ELK1	O75582	RPS6KA5	S198	G195R	195	Missense	distal	-3	no	1.152	2.145	EPSD	TCGA;COSMIC	1.456	Gain
AGC_RSK_MSK_RPS6KA5_ST	P19419	ELK1	O75582	RPS6KA5	T199	S196R	196	Missense	distal	-3	no	0.954	1.824	EPSD	TCGA;ICGC;COSMIC	1.456	Gain
AGC_RSK_MSK_RPS6KA5_ST	P19419	ELK1	O75582	RPS6KA5	S200	S194L	194	Missense	distal	-6	no	2.123	2.108	EPSD	TCGA;ICGC;COSMIC	1.456	Down-regulation
AGC_RSK_MSK_RPS6KA5_ST	P19419	ELK1	O75582	RPS6KA5	S200	S196R	196	Missense	distal	-4	no	2.123	2.029	EPSD	TCGA;ICGC;COSMIC	1.456	Down-regulation
AGC_RSK_MSK_RPS6KA5_ST	P19419	ELK1	O75582	RPS6KA5	S200	P201L	201	Missense	proximal	1	no	2.123	2.120	EPSD	TCGA;ICGC;COSMIC	1.456	Down-regulation
AGC_RSK_MSK_RPS6KA5_ST	P19419	ELK1	O75582	RPS6KA5	S200	G195R	195	Missense	distal	-5	no	2.123	2.164	EPSD	TCGA;COSMIC	1.456	Up-regulation
AGC_RSK_MSK_RPS6KA5_ST	P19419	ELK1	O75582	RPS6KA5	S303	S308C	308	Missense	distal	5	no	1.903	1.896	EPSD	TCGA;ICGC;COSMIC	1.456	Down-regulation
AGC_RSK_MSK_RPS6KA5_ST	P19419	ELK1	O75582	RPS6KA5	S303	A301V	301	Missense	proximal	-2	no	1.903	1.165	EPSD	TCGA;ICGC	1.456	Loss
AGC_RSK_MSK_RPS6KA5_ST	P19419	ELK1	O75582	RPS6KA5	S303	G298V	298	Missense	distal	-5	no	1.903	1.898	EPSD	TCGA;ICGC;COSMIC	1.456	Down-regulation
AGC_RSK_MSK_RPS6KA5_ST	P19419	ELK1	O75582	RPS6KA5	S303	S303Y	303	Missense	central	0	yes	1.903	0.000	EPSD	TCGA;ICGC;COSMIC	1.456	Loss
AGC_RSK_MSK_RPS6KA5_ST	P19419	ELK1	O75582	RPS6KA5	S304	S308C	308	Missense	distal	4	no	1.739	1.732	EPSD	TCGA;ICGC;COSMIC	1.456	Down-regulation
AGC_RSK_MSK_RPS6KA5_ST	P19419	ELK1	O75582	RPS6KA5	S304	A301V	301	Missense	distal	-3	no	1.739	1.319	EPSD	TCGA;ICGC	1.456	Loss
AGC_RSK_MSK_RPS6KA5_ST	P19419	ELK1	O75582	RPS6KA5	S304	G298V	298	Missense	distal	-6	no	1.739	1.749	EPSD	TCGA;ICGC;COSMIC	1.456	Up-regulation
AGC_RSK_MSK_RPS6KA5_ST	P19419	ELK1	O75582	RPS6KA5	S304	S303Y	303	Missense	proximal	-1	no	1.739	1.735	EPSD	TCGA;ICGC;COSMIC	1.456	Down-regulation
AGC_RSK_MSK_RPS6KA5_ST	P07101	TH	O75582	RPS6KA5	S19	A23T	23	Missense	distal	4	no	2.445	2.384	EPSD	TCGA;ICGC;COSMIC	1.456	Down-regulation
AGC_RSK_MSK_RPS6KA5_ST	P07101	TH	O75582	RPS6KA5	S19	R15H	15	Missense	distal	-4	no	2.445	2.546	EPSD	TCGA;ICGC;COSMIC;GDSC	1.456	Up-regulation
AGC_RSK_MSK_RPS6KA5_ST	P07101	TH	O75582	RPS6KA5	S71	R64W	64	Missense	distal	-7	no	3.730	3.801	EPSD	TCGA;COSMIC	1.456	Up-regulation
AGC_RSK_MSK_RPS6KA5_ST	P07101	TH	O75582	RPS6KA5	S71	K78N	78	Missense	distal	7	no	3.730	3.748	EPSD	TCGA;COSMIC	1.456	Up-regulation
AGC_RSK_MSK_RPS6KA5_ST	P07101	TH	O75582	RPS6KA5	S509	R508H	508	Missense	proximal	-1	no	2.614	2.585	EPSD	TCGA	1.456	Down-regulation
AGC_RSK_MSK_RPS6KA5_ST	P07101	TH	O75582	RPS6KA5	S509	R508S	508	Missense	proximal	-1	no	2.614	2.584	EPSD	TCGA;COSMIC	1.456	Down-regulation
TK_EGFR_EGFR_Y	P52735	VAV2	P00533	EGFR	Y159	P163S	163	Missense	distal	4	no	15.767	15.205	EPSD;PhosphoSitePlus	TCGA;ICGC;CCLE	6.466	Down-regulation
TK_EGFR_EGFR_Y	P52735	VAV2	P00533	EGFR	Y172	E179A	179	Missense	distal	7	no	12.223	12.231	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	6.466	Up-regulation
TK_EGFR_EGFR_Y	P52735	VAV2	P00533	EGFR	Y172	E173K	173	Missense	proximal	1	no	12.223	12.215	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	6.466	Down-regulation
TK_EGFR_EGFR_Y	P52735	VAV2	P00533	EGFR	Y172	D169Y	169	Missense	distal	-3	no	12.223	10.209	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	6.466	Down-regulation
TK_EGFR_EGFR_Y	P52735	VAV2	P00533	EGFR	Y172	E179D	179	Missense	distal	7	no	12.223	12.079	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	6.466	Down-regulation
TK_EGFR_EGFR_Y	P52735	VAV2	P00533	EGFR	Y172	Y172H	172	Missense	central	0	yes	12.223	0.000	EPSD;PhosphoSitePlus	TCGA;ICGC	6.466	Loss
TK_EGFR_EGFR_Y	P52735	VAV2	P00533	EGFR	Y224	P227S	227	Missense	distal	3	no	6.534	6.902	EPSD	TCGA;COSMIC	6.466	Up-regulation
TK_EGFR_EGFR_Y	P52735	VAV2	P00533	EGFR	Y549	F543I	543	Missense	distal	-6	no	8.366	8.364	EPSD	TCGA;COSMIC	6.466	Down-regulation
TK_EGFR_EGFR_Y	Q8NFJ5	GPRC5A	P00533	EGFR	Y300	E303Q	303	Missense	distal	3	no	5.841	6.495	EPSD	TCGA;ICGC;COSMIC	6.466	Gain
TK_EGFR_EGFR_Y	Q8NFJ5	GPRC5A	P00533	EGFR	Y317	Y320F	320	Missense	distal	3	no	9.261	9.386	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	6.466	Up-regulation
TK_EGFR_EGFR_Y	Q8NFJ5	GPRC5A	P00533	EGFR	Y320	Y320F	320	Missense	central	0	yes	8.152	0.000	PhosphoSitePlus;EPSD	TCGA;ICGC;COSMIC	6.466	Loss
TK_EGFR_EGFR_Y	P29353	SHC1	P00533	EGFR	Y349	P354A	354	Missense	distal	5	no	12.290	12.532	EPSD	TCGA;COSMIC	6.466	Up-regulation
TK_EGFR_EGFR_Y	P29353	SHC1	P00533	EGFR	Y349	F353L	353	Missense	distal	4	no	12.290	12.251	EPSD	TCGA;COSMIC	6.466	Down-regulation
TK_EGFR_EGFR_Y	P29353	SHC1	P00533	EGFR	Y349	P344S	344	Missense	distal	-5	no	12.290	12.653	EPSD	TCGA;COSMIC	6.466	Up-regulation
TK_EGFR_EGFR_Y	P29353	SHC1	P00533	EGFR	Y350	P354A	354	Missense	distal	4	no	13.414	13.098	EPSD	TCGA;COSMIC	6.466	Down-regulation
TK_EGFR_EGFR_Y	P29353	SHC1	P00533	EGFR	Y350	E357K	357	Missense	distal	7	no	13.414	13.402	EPSD	TCGA;COSMIC	6.466	Down-regulation
TK_EGFR_EGFR_Y	P29353	SHC1	P00533	EGFR	Y350	F353L	353	Missense	distal	3	no	13.414	14.036	EPSD	TCGA;COSMIC	6.466	Up-regulation
TK_EGFR_EGFR_Y	P29353	SHC1	P00533	EGFR	Y350	P344S	344	Missense	distal	-6	no	13.414	13.426	EPSD	TCGA;COSMIC	6.466	Up-regulation
TK_EGFR_EGFR_Y	Q01813	PFKP	P00533	EGFR	Y52	G50S	50	Missense	proximal	-2	no	5.082	7.503	EPSD	TCGA;COSMIC	6.466	Gain
TK_EGFR_EGFR_Y	Q8IVM0	CCDC50	P00533	EGFR	Y145	Y144C	144	Missense	proximal	-1	no	6.831	7.189	EPSD	TCGA;ICGC;COSMIC	6.466	Up-regulation
TK_EGFR_EGFR_Y	Q8IVM0	CCDC50	P00533	EGFR	Y145	G149E	149	Missense	distal	4	no	6.831	6.430	EPSD	TCGA;ICGC;COSMIC	6.466	Loss
TK_EGFR_EGFR_Y	Q8IVM0	CCDC50	P00533	EGFR	Y145	A141T	141	Missense	distal	-4	no	6.831	7.459	EPSD	TCGA;ICGC;COSMIC	6.466	Up-regulation
TK_EGFR_EGFR_Y	P00533	EGFR	P00533	EGFR	Y764	S768I	768	Missense	distal	4	no	8.694	9.039	EPSD	TCGA;COSMIC;GDSC;CCLE	6.466	Up-regulation
TK_EGFR_EGFR_Y	P00533	EGFR	P00533	EGFR	Y764	I759N	759	Missense	distal	-5	no	8.694	9.054	EPSD	TCGA;COSMIC	6.466	Up-regulation
TK_EGFR_EGFR_Y	P00533	EGFR	P00533	EGFR	Y764	V769L	769	Missense	distal	5	no	8.694	8.586	EPSD	TCGA;COSMIC	6.466	Down-regulation
TK_EGFR_EGFR_Y	P00533	EGFR	P00533	EGFR	Y869	E872G	872	Missense	distal	3	no	12.957	13.517	EPSD;PhosphoSitePlus	TCGA;COSMIC	6.466	Up-regulation
TK_EGFR_EGFR_Y	P00533	EGFR	P00533	EGFR	Y869	E866K	866	Missense	distal	-3	no	12.957	10.251	EPSD;PhosphoSitePlus	TCGA;COSMIC	6.466	Down-regulation
TK_EGFR_EGFR_Y	P00533	EGFR	P00533	EGFR	Y869	A864V	864	Missense	distal	-5	no	12.957	11.992	EPSD;PhosphoSitePlus	TCGA;COSMIC;GDSC	6.466	Down-regulation
TK_EGFR_EGFR_Y	P00533	EGFR	P00533	EGFR	Y998	A1000V	1000	Missense	proximal	2	no	7.773	6.461	EPSD	TCGA;COSMIC	6.466	Loss
TK_EGFR_EGFR_Y	P00533	EGFR	P00533	EGFR	Y998	F997V	997	Missense	proximal	-1	no	7.773	6.480	EPSD	TCGA;COSMIC	6.466	Down-regulation
TK_EGFR_EGFR_Y	P00533	EGFR	P00533	EGFR	Y1016	P1019L	1019	Missense	distal	3	no	9.841	10.463	PhosphoSitePlus;EPSD	TCGA;COSMIC	6.466	Up-regulation
TK_EGFR_EGFR_Y	P00533	EGFR	P00533	EGFR	Y1016	D1009N	1009	Missense	distal	-7	no	9.841	9.521	PhosphoSitePlus;EPSD	TCGA;COSMIC	6.466	Down-regulation
TK_EGFR_EGFR_Y	P00533	EGFR	P00533	EGFR	Y1092	V1097I	1097	Missense	distal	5	no	10.686	10.689	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	6.466	Up-regulation
TK_EGFR_EGFR_Y	P00533	EGFR	P00533	EGFR	Y1092	S1096F	1096	Missense	distal	4	no	10.686	11.431	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	6.466	Up-regulation
TK_EGFR_EGFR_Y	P00533	EGFR	P00533	EGFR	Y1092	N1094S	1094	Missense	proximal	2	no	10.686	9.128	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	6.466	Down-regulation
TK_EGFR_EGFR_Y	P00533	EGFR	P00533	EGFR	Y1125	P1123S	1123	Missense	proximal	-2	no	11.851	12.114	EPSD	TCGA;ICGC	6.466	Up-regulation
TK_EGFR_EGFR_Y	P00533	EGFR	P00533	EGFR	Y1138	L1139F	1139	Missense	proximal	1	no	10.965	11.519	EPSD	TCGA;COSMIC	6.466	Up-regulation
TK_EGFR_EGFR_Y	P00533	EGFR	P00533	EGFR	Y1138	Y1138C	1138	Missense	central	0	yes	10.965	0.000	EPSD	TCGA;ICGC;COSMIC	6.466	Loss
TK_EGFR_EGFR_Y	P00533	EGFR	P00533	EGFR	Y1172	P1178L	1178	Missense	distal	6	no	9.835	9.448	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	6.466	Down-regulation
TK_EGFR_EGFR_Y	P00533	EGFR	P00533	EGFR	Y1172	L1167M	1167	Missense	distal	-5	no	9.835	9.874	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	6.466	Up-regulation
TK_EGFR_EGFR_Y	P35222	CTNNB1	P00533	EGFR	Y30	G34R	34	Missense	distal	4	no	6.275	6.735	EPSD	TCGA;COSMIC	6.466	Gain
TK_EGFR_EGFR_Y	P35222	CTNNB1	P00533	EGFR	Y30	S37A	37	Missense	distal	7	no	6.275	6.539	EPSD	TCGA;COSMIC;GDSC;CCLE	6.466	Gain
TK_EGFR_EGFR_Y	P35222	CTNNB1	P00533	EGFR	Y30	S37P	37	Missense	distal	7	no	6.275	6.497	EPSD	TCGA;COSMIC;GDSC;CCLE	6.466	Gain
TK_EGFR_EGFR_Y	P35222	CTNNB1	P00533	EGFR	Y142	I140N	140	Missense	proximal	-2	no	5.935	9.311	PhosphoSitePlus;EPSD	TCGA	6.466	Gain
TK_EGFR_EGFR_Y	P35222	CTNNB1	P00533	EGFR	Y654	E649Q	649	Missense	distal	-5	no	6.536	5.479	EPSD;PhosphoSitePlus	TCGA;COSMIC	6.466	Loss
TK_EGFR_EGFR_Y	P35222	CTNNB1	P00533	EGFR	Y654	T653K	653	Missense	proximal	-1	no	6.536	5.914	EPSD;PhosphoSitePlus	TCGA;COSMIC	6.466	Loss
TK_EGFR_EGFR_Y	P35222	CTNNB1	P00533	EGFR	Y716	R717H	717	Missense	proximal	1	no	7.581	8.917	EPSD	TCGA;COSMIC	6.466	Up-regulation
TK_EGFR_EGFR_Y	P35222	CTNNB1	P00533	EGFR	Y716	P714R	714	Missense	proximal	-2	no	7.581	5.212	EPSD	TCGA;COSMIC	6.466	Loss
TK_EGFR_EGFR_Y	P35222	CTNNB1	P00533	EGFR	Y716	P714L	714	Missense	proximal	-2	no	7.581	2.160	EPSD	TCGA;COSMIC	6.466	Loss
TK_EGFR_EGFR_Y	P19174	PLCG1	P00533	EGFR	Y472	M479I	479	Missense	distal	7	no	10.012	9.897	EPSD	TCGA;ICGC;COSMIC	6.466	Down-regulation
TK_EGFR_EGFR_Y	P19174	PLCG1	P00533	EGFR	Y496	G493S	493	Missense	distal	-3	no	6.447	6.750	EPSD	TCGA	6.466	Gain
TK_EGFR_EGFR_Y	P19174	PLCG1	P00533	EGFR	Y496	G493D	493	Missense	distal	-3	no	6.447	9.005	EPSD	TCGA;ICGC	6.466	Gain
TK_EGFR_EGFR_Y	P19174	PLCG1	P00533	EGFR	Y702	R696W	696	Missense	distal	-6	no	7.167	7.119	EPSD	TCGA;ICGC;COSMIC	6.466	Down-regulation
TK_EGFR_EGFR_Y	P19174	PLCG1	P00533	EGFR	Y771	A767P	767	Missense	distal	-4	no	10.925	10.449	PhosphoSitePlus;EPSD	TCGA;ICGC;COSMIC	6.466	Down-regulation
TK_EGFR_EGFR_Y	P19174	PLCG1	P00533	EGFR	Y771	R778C	778	Missense	distal	7	no	10.925	10.649	PhosphoSitePlus;EPSD	TCGA;ICGC;COSMIC;GDSC;CCLE	6.466	Down-regulation
TK_EGFR_EGFR_Y	P19174	PLCG1	P00533	EGFR	Y783	F782L	782	Missense	proximal	-1	no	8.649	8.370	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	6.466	Down-regulation
TK_EGFR_EGFR_Y	P19174	PLCG1	P00533	EGFR	Y783	P788H	788	Missense	distal	5	no	8.649	8.760	EPSD;PhosphoSitePlus	TCGA;ICGC	6.466	Up-regulation
TK_EGFR_EGFR_Y	P19174	PLCG1	P00533	EGFR	Y783	R778C	778	Missense	distal	-5	no	8.649	8.467	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC;GDSC;CCLE	6.466	Down-regulation
TK_EGFR_EGFR_Y	Q05397	PTK2	P00533	EGFR	Y194	V201I	201	Missense	distal	7	no	15.865	15.755	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	6.466	Down-regulation
TK_EGFR_EGFR_Y	Q05397	PTK2	P00533	EGFR	Y397	E403K	403	Missense	distal	6	no	17.838	17.880	EPSD	TCGA;ICGC;COSMIC	6.466	Up-regulation
TK_EGFR_EGFR_Y	Q05397	PTK2	P00533	EGFR	Y397	D395Y	395	Missense	proximal	-2	no	17.838	13.732	EPSD	TCGA;ICGC	6.466	Down-regulation
TK_EGFR_EGFR_Y	Q05397	PTK2	P00533	EGFR	Y397	E404G	404	Missense	distal	7	no	17.838	17.904	EPSD	TCGA;ICGC;COSMIC	6.466	Up-regulation
TK_EGFR_EGFR_Y	Q05397	PTK2	P00533	EGFR	Y407	E403K	403	Missense	distal	-4	no	12.749	10.636	EPSD	TCGA;ICGC;COSMIC	6.466	Down-regulation
TK_EGFR_EGFR_Y	Q05397	PTK2	P00533	EGFR	Y407	E404G	404	Missense	distal	-3	no	12.749	9.095	EPSD	TCGA;ICGC;COSMIC	6.466	Down-regulation
TK_EGFR_EGFR_Y	Q05397	PTK2	P00533	EGFR	Y742	N740D	740	Missense	proximal	-2	no	7.192	7.144	EPSD	TCGA;ICGC;COSMIC	6.466	Down-regulation
TK_EGFR_EGFR_Y	Q05397	PTK2	P00533	EGFR	Y742	N740K	740	Missense	proximal	-2	no	7.192	4.229	EPSD	TCGA;ICGC;COSMIC	6.466	Loss
TK_EGFR_EGFR_Y	Q05397	PTK2	P00533	EGFR	Y742	N740S	740	Missense	proximal	-2	no	7.192	6.328	EPSD	TCGA;ICGC;COSMIC	6.466	Loss
TK_EGFR_EGFR_Y	P12004	PCNA	P00533	EGFR	Y211	F215C	215	Missense	distal	4	no	7.900	7.869	PhosphoSitePlus	TCGA;ICGC;COSMIC	6.466	Down-regulation
TK_EGFR_EGFR_Y	P12004	PCNA	P00533	EGFR	Y211	Y211H	211	Missense	central	0	yes	7.900	0.000	PhosphoSitePlus	TCGA;ICGC;COSMIC	6.466	Loss
TK_EGFR_EGFR_Y	Q13480	GAB1	P00533	EGFR	Y83	I84V	84	Missense	proximal	1	no	5.314	6.978	EPSD	TCGA;ICGC;COSMIC	6.466	Gain
TK_EGFR_EGFR_Y	Q13480	GAB1	P00533	EGFR	Y259	L261R	261	Missense	proximal	2	no	6.306	7.675	EPSD	TCGA;ICGC;COSMIC	6.466	Gain
TK_EGFR_EGFR_Y	Q13480	GAB1	P00533	EGFR	Y285	T289N	289	Missense	distal	4	no	10.197	9.504	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	6.466	Down-regulation
TK_EGFR_EGFR_Y	Q13480	GAB1	P00533	EGFR	Y307	P310S	310	Missense	distal	3	no	7.462	7.830	EPSD	TCGA;ICGC;COSMIC	6.466	Up-regulation
TK_EGFR_EGFR_Y	Q13480	GAB1	P00533	EGFR	Y373	D370N	370	Missense	distal	-3	no	9.862	8.528	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	6.466	Down-regulation
TK_EGFR_EGFR_Y	Q13480	GAB1	P00533	EGFR	Y373	S367L	367	Missense	distal	-6	no	9.862	9.856	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	6.466	Down-regulation
TK_EGFR_EGFR_Y	Q13480	GAB1	P00533	EGFR	Y406	R410Q	410	Missense	distal	4	no	12.131	11.515	PhosphoSitePlus;EPSD	TCGA;ICGC;COSMIC	6.466	Down-regulation
TK_EGFR_EGFR_Y	Q13480	GAB1	P00533	EGFR	Y447	P452L	452	Missense	distal	5	no	12.802	12.761	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	6.466	Down-regulation
TK_EGFR_EGFR_Y	Q13480	GAB1	P00533	EGFR	Y447	M450K	450	Missense	distal	3	no	12.802	12.238	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	6.466	Down-regulation
TK_EGFR_EGFR_Y	Q14457	BECN1	P00533	EGFR	Y352	K347N	347	Missense	distal	-5	no	6.266	6.550	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	6.466	Gain
TK_EGFR_EGFR_Y	O14939	PLD2	P00533	EGFR	Y179	R180C	180	Missense	proximal	1	no	6.029	7.857	EPSD	TCGA;ICGC;COSMIC	6.466	Gain
TK_EGFR_EGFR_Y	O14939	PLD2	P00533	EGFR	Y296	R300Q	300	Missense	distal	4	no	8.334	7.719	PhosphoSitePlus	TCGA;ICGC;COSMIC	6.466	Down-regulation
TK_EGFR_EGFR_Y	P40818	USP8	P00533	EGFR	Y717	P720Q	720	Missense	distal	3	no	9.285	9.527	PhosphoSitePlus;EPSD	TCGA;ICGC;COSMIC;GDSC	6.466	Up-regulation
TK_EGFR_EGFR_Y	P40818	USP8	P00533	EGFR	Y717	P720A	720	Missense	distal	3	no	9.285	9.678	PhosphoSitePlus;EPSD	TCGA;ICGC;COSMIC	6.466	Up-regulation
TK_EGFR_EGFR_Y	P40818	USP8	P00533	EGFR	Y717	S716F	716	Missense	proximal	-1	no	9.285	8.888	PhosphoSitePlus;EPSD	TCGA;ICGC;COSMIC	6.466	Down-regulation
TK_EGFR_EGFR_Y	P40818	USP8	P00533	EGFR	Y717	R715C	715	Missense	proximal	-2	no	9.285	7.719	PhosphoSitePlus;EPSD	TCGA;ICGC;COSMIC	6.466	Down-regulation
TK_EGFR_EGFR_Y	P40818	USP8	P00533	EGFR	Y717	P720S	720	Missense	distal	3	no	9.285	9.653	PhosphoSitePlus;EPSD	TCGA;ICGC	6.466	Up-regulation
TK_EGFR_EGFR_Y	P40818	USP8	P00533	EGFR	Y810	Q811K	811	Missense	proximal	1	no	10.647	9.646	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	6.466	Down-regulation
TK_EGFR_EGFR_Y	O00767	SCD	P00533	EGFR	Y41	T37M	37	Missense	distal	-4	no	13.605	12.996	PhosphoSitePlus;EPSD	TCGA;ICGC;COSMIC;GDSC;CCLE	6.466	Down-regulation
TK_EGFR_EGFR_Y	O00767	SCD	P00533	EGFR	Y55	K51Q	51	Missense	distal	-4	no	15.341	15.548	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	6.466	Up-regulation
TK_EGFR_EGFR_Y	O00767	SCD	P00533	EGFR	Y55	D52Y	52	Missense	distal	-3	no	15.341	13.328	EPSD;PhosphoSitePlus	TCGA;ICGC	6.466	Down-regulation
TK_EGFR_EGFR_Y	O00767	SCD	P00533	EGFR	Y59	D52Y	52	Missense	distal	-7	no	8.552	7.644	EPSD	TCGA;ICGC	6.466	Down-regulation
TK_EGFR_EGFR_Y	P04083	ANXA1	P00533	EGFR	Y21	S27L	27	Missense	distal	6	no	11.664	11.382	PhosphoSitePlus	TCGA;ICGC;COSMIC	6.466	Down-regulation
TK_EGFR_EGFR_Y	P04083	ANXA1	P00533	EGFR	Y21	E17K	17	Missense	distal	-4	no	11.664	9.552	PhosphoSitePlus	TCGA;ICGC;COSMIC	6.466	Down-regulation
TK_EGFR_EGFR_Y	P11171	EPB41	P00533	EGFR	Y660	E657K	657	Missense	distal	-3	no	11.750	9.043	EPSD	TCGA;COSMIC	6.466	Down-regulation
TK_EGFR_EGFR_Y	Q9UBN7	HDAC6	P00533	EGFR	Y570	F566L	566	Missense	distal	-4	no	9.897	8.027	PhosphoSitePlus	TCGA;COSMIC	6.466	Down-regulation
TK_EGFR_EGFR_Y	Q9UBN7	HDAC6	P00533	EGFR	Y570	D567H	567	Missense	distal	-3	no	9.897	7.784	PhosphoSitePlus	TCGA;COSMIC	6.466	Down-regulation
TK_EGFR_EGFR_Y	Q9UBN7	HDAC6	P00533	EGFR	Y570	I571S	571	Missense	proximal	1	no	9.897	10.137	PhosphoSitePlus	TCGA;COSMIC	6.466	Up-regulation
TK_EGFR_EGFR_Y	Q38SD2	LRRK1	P00533	EGFR	Y971	E969D	969	Missense	proximal	-2	no	11.746	11.481	PhosphoSitePlus	TCGA;COSMIC	6.466	Down-regulation
TK_EGFR_EGFR_Y	Q13315	ATM	P00533	EGFR	Y370	Q368E	368	Missense	proximal	-2	no	7.915	9.925	PhosphoSitePlus	TCGA;ICGC;COSMIC	6.466	Up-regulation
TK_EGFR_EGFR_Y	Q13315	ATM	P00533	EGFR	Y2969	R2973T	2973	Missense	distal	4	no	9.042	8.682	EPSD	TCGA;ICGC;COSMIC	6.466	Down-regulation
TK_EGFR_EGFR_Y	Q13315	ATM	P00533	EGFR	Y2969	Q2972H	2972	Missense	distal	3	no	9.042	8.646	EPSD	TCGA;ICGC;COSMIC	6.466	Down-regulation
TK_EGFR_EGFR_Y	O00291	HIP1	P00533	EGFR	Y862	K864N	864	Missense	proximal	2	no	5.160	7.167	EPSD	TCGA;COSMIC	6.466	Gain
TK_EGFR_EGFR_Y	O95477	ABCA1	P00533	EGFR	Y325	L322F	322	Missense	distal	-3	no	9.459	10.743	EPSD	TCGA;ICGC;COSMIC	6.466	Up-regulation
TK_EGFR_EGFR_Y	O95477	ABCA1	P00533	EGFR	Y325	D327H	327	Missense	proximal	2	no	9.459	7.847	EPSD	TCGA;ICGC	6.466	Down-regulation
TK_EGFR_EGFR_Y	O15492	RGS16	P00533	EGFR	Y168	P169S	169	Missense	proximal	1	no	10.754	9.899	PhosphoSitePlus	TCGA;ICGC;COSMIC	6.466	Down-regulation
TK_EGFR_EGFR_Y	O15492	RGS16	P00533	EGFR	Y168	S174L	174	Missense	distal	6	no	10.754	10.472	PhosphoSitePlus	TCGA;ICGC;COSMIC	6.466	Down-regulation
TK_EGFR_EGFR_Y	O15492	RGS16	P00533	EGFR	Y168	L162P	162	Missense	distal	-6	no	10.754	10.749	PhosphoSitePlus	TCGA;ICGC	6.466	Down-regulation
TK_EGFR_EGFR_Y	O15492	RGS16	P00533	EGFR	Y177	R178W	178	Missense	proximal	1	no	7.375	8.088	EPSD	TCGA;ICGC;COSMIC	6.466	Up-regulation
TK_EGFR_EGFR_Y	O15492	RGS16	P00533	EGFR	Y177	S174L	174	Missense	distal	-3	no	7.375	5.096	EPSD	TCGA;ICGC;COSMIC	6.466	Loss
TK_EGFR_EGFR_Y	Q9P219	CCDC88C	P00533	EGFR	Y219	P225L	225	Missense	distal	6	no	11.339	10.953	EPSD	TCGA;ICGC;COSMIC	6.466	Down-regulation
TK_EGFR_EGFR_Y	P18031	PTPN1	P00533	EGFR	Y46	D53H	53	Missense	distal	7	no	7.735	7.552	EPSD	TCGA;COSMIC	6.466	Down-regulation
TK_EGFR_EGFR_Y	P18031	PTPN1	P00533	EGFR	Y46	Y46H	46	Missense	central	0	yes	7.735	0.000	EPSD	TCGA;ICGC;COSMIC	6.466	Loss
TK_EGFR_EGFR_Y	P18031	PTPN1	P00533	EGFR	Y46	D48Y	48	Missense	proximal	2	no	7.735	4.826	EPSD	TCGA;ICGC;COSMIC	6.466	Loss
TK_EGFR_EGFR_Y	P18031	PTPN1	P00533	EGFR	Y46	P51L	51	Missense	distal	5	no	7.735	7.694	EPSD	TCGA;ICGC	6.466	Down-regulation
TK_EGFR_EGFR_Y	P18031	PTPN1	P00533	EGFR	Y46	R43Q	43	Missense	distal	-3	no	7.735	8.402	EPSD	TCGA;ICGC	6.466	Up-regulation
TK_EGFR_EGFR_Y	P15311	EZR	P00533	EGFR	Y116	G109R	109	Missense	distal	-7	no	10.057	10.336	EPSD	TCGA;ICGC;COSMIC	6.466	Up-regulation
TK_EGFR_EGFR_Y	P15311	EZR	P00533	EGFR	Y116	L111F	111	Missense	distal	-5	no	10.057	9.758	EPSD	TCGA;ICGC;COSMIC	6.466	Down-regulation
TK_EGFR_EGFR_Y	P15311	EZR	P00533	EGFR	Y146	S148R	148	Missense	proximal	2	no	8.664	7.190	EPSD;PhosphoSitePlus	TCGA;ICGC	6.466	Down-regulation
TK_EGFR_EGFR_Y	P15311	EZR	P00533	EGFR	Y205	K211N	211	Missense	distal	6	no	7.639	7.768	EPSD	TCGA;ICGC;COSMIC	6.466	Up-regulation
TK_EGFR_EGFR_Y	P15311	EZR	P00533	EGFR	Y205	G202V	202	Missense	distal	-3	no	7.639	6.716	EPSD	TCGA;ICGC	6.466	Down-regulation
TK_EGFR_EGFR_Y	P15311	EZR	P00533	EGFR	Y205	E207K	207	Missense	proximal	2	no	7.639	5.741	EPSD	TCGA;ICGC	6.466	Loss
TK_EGFR_EGFR_Y	P15311	EZR	P00533	EGFR	Y354	K359N	359	Missense	distal	5	no	8.003	8.099	PhosphoSitePlus;EPSD	TCGA;ICGC;COSMIC	6.466	Up-regulation
TK_EGFR_EGFR_Y	P15311	EZR	P00533	EGFR	Y354	D353N	353	Missense	proximal	-1	no	8.003	7.630	PhosphoSitePlus;EPSD	TCGA;ICGC;COSMIC	6.466	Down-regulation
TK_EGFR_EGFR_Y	P15311	EZR	P00533	EGFR	Y424	K427N	427	Missense	distal	3	no	8.292	9.329	EPSD	TCGA;ICGC;COSMIC	6.466	Up-regulation
TK_EGFR_EGFR_Y	P15311	EZR	P00533	EGFR	Y424	T425I	425	Missense	proximal	1	no	8.292	7.679	EPSD	TCGA;ICGC;COSMIC	6.466	Down-regulation
TK_EGFR_EGFR_Y	P15311	EZR	P00533	EGFR	Y424	A426V	426	Missense	proximal	2	no	8.292	6.980	EPSD	TCGA;ICGC;COSMIC	6.466	Down-regulation
TK_EGFR_EGFR_Y	P15311	EZR	P00533	EGFR	Y499	A501V	501	Missense	proximal	2	no	12.598	11.286	EPSD	TCGA;ICGC	6.466	Down-regulation
TK_EGFR_EGFR_Y	Q92529	SHC3	P00533	EGFR	Y341	H339Q	339	Missense	proximal	-2	no	8.084	9.643	EPSD	TCGA;ICGC;COSMIC	6.466	Up-regulation
TK_EGFR_EGFR_Y	Q92529	SHC3	P00533	EGFR	Y341	S347I	347	Missense	distal	6	no	8.084	8.166	EPSD	TCGA;ICGC	6.466	Up-regulation
TK_EGFR_EGFR_Y	Q92529	SHC3	P00533	EGFR	Y342	H339Q	339	Missense	distal	-3	no	9.915	10.164	EPSD	TCGA;ICGC;COSMIC	6.466	Up-regulation
TK_EGFR_EGFR_Y	Q92529	SHC3	P00533	EGFR	Y342	S347I	347	Missense	distal	5	no	9.915	9.758	EPSD	TCGA;ICGC	6.466	Down-regulation
TK_EGFR_EGFR_Y	Q92529	SHC3	P00533	EGFR	Y379	G386E	386	Missense	distal	7	no	12.223	12.157	EPSD	TCGA;ICGC;COSMIC	6.466	Down-regulation
TK_EGFR_EGFR_Y	Q92529	SHC3	P00533	EGFR	Y379	E376K	376	Missense	distal	-3	no	12.223	9.517	EPSD	TCGA;ICGC;COSMIC	6.466	Down-regulation
TK_EGFR_EGFR_Y	Q92529	SHC3	P00533	EGFR	Y379	L385S	385	Missense	distal	6	no	12.223	12.505	EPSD	TCGA;ICGC;COSMIC	6.466	Up-regulation
TK_EGFR_EGFR_Y	Q92529	SHC3	P00533	EGFR	Y380	G386E	386	Missense	distal	6	no	8.585	8.778	EPSD	TCGA;ICGC;COSMIC	6.466	Up-regulation
TK_EGFR_EGFR_Y	Q92529	SHC3	P00533	EGFR	Y380	E376K	376	Missense	distal	-4	no	8.585	6.472	EPSD	TCGA;ICGC;COSMIC	6.466	Down-regulation
TK_EGFR_EGFR_Y	Q92529	SHC3	P00533	EGFR	Y380	L385S	385	Missense	distal	5	no	8.585	8.853	EPSD	TCGA;ICGC;COSMIC	6.466	Up-regulation
TK_EGFR_EGFR_Y	Q92529	SHC3	P00533	EGFR	Y406	D404N	404	Missense	proximal	-2	no	12.044	12.092	EPSD	TCGA;ICGC;COSMIC	6.466	Up-regulation
TK_EGFR_EGFR_Y	Q92529	SHC3	P00533	EGFR	Y406	S402F	402	Missense	distal	-4	no	12.044	12.753	EPSD	TCGA;ICGC;COSMIC	6.466	Up-regulation
TK_EGFR_EGFR_Y	Q92529	SHC3	P00533	EGFR	Y406	D404G	404	Missense	proximal	-2	no	12.044	8.806	EPSD	TCGA;ICGC	6.466	Down-regulation
TK_EGFR_EGFR_Y	Q92529	SHC3	P00533	EGFR	Y424	T418A	418	Missense	distal	-6	no	11.166	11.219	EPSD	TCGA;ICGC;COSMIC	6.466	Up-regulation
TK_EGFR_EGFR_Y	Q92529	SHC3	P00533	EGFR	Y424	T418M	418	Missense	distal	-6	no	11.166	11.164	EPSD	TCGA;ICGC;COSMIC	6.466	Down-regulation
TK_EGFR_EGFR_Y	P07948	LYN	P00533	EGFR	Y32	R29I	29	Missense	distal	-3	no	9.229	7.324	PhosphoSitePlus	TCGA;ICGC	6.466	Down-regulation
TK_EGFR_EGFR_Y	P07948	LYN	P00533	EGFR	Y117	K120T	120	Missense	distal	3	no	7.078	7.800	EPSD	TCGA;ICGC;COSMIC	6.466	Up-regulation
TK_EGFR_EGFR_Y	P07948	LYN	P00533	EGFR	Y397	K404N	404	Missense	distal	7	no	8.824	8.979	EPSD	TCGA;ICGC;COSMIC	6.466	Up-regulation
TK_EGFR_EGFR_Y	P48050	KCNJ4	P00533	EGFR	Y234	Q239K	239	Missense	distal	5	no	8.609	8.535	PhosphoSitePlus	TCGA;ICGC;COSMIC	6.466	Down-regulation
TK_EGFR_EGFR_Y	P48050	KCNJ4	P00533	EGFR	Y234	G232S	232	Missense	proximal	-2	no	8.609	11.031	PhosphoSitePlus	TCGA;ICGC;COSMIC	6.466	Up-regulation
TK_EGFR_EGFR_Y	P14618	PKM	P00533	EGFR	Y105	R106Q	106	Missense	proximal	1	no	5.238	7.062	EPSD	TCGA;ICGC;COSMIC	6.466	Gain
TK_EGFR_EGFR_Y	P14618	PKM	P00533	EGFR	Y148	L144P	144	Missense	distal	-4	no	10.187	10.690	PhosphoSitePlus	TCGA;ICGC;COSMIC	6.466	Up-regulation
TK_EGFR_EGFR_Y	P14618	PKM	P00533	EGFR	Y175	G171D	171	Missense	distal	-4	no	7.028	6.706	EPSD	TCGA;ICGC;COSMIC	6.466	Down-regulation
TK_EGFR_EGFR_Y	P14618	PKM	P00533	EGFR	Y390	E396D	396	Missense	distal	6	no	7.756	7.179	EPSD	TCGA;COSMIC	6.466	Down-regulation
TK_EGFR_EGFR_Y	P14618	PKM	P00533	EGFR	Y390	R383C	383	Missense	distal	-7	no	7.756	7.121	EPSD	TCGA;GDSC	6.466	Down-regulation
TK_EGFR_EGFR_Y	Q8TDY4	ASAP3	P00533	EGFR	Y76	L83S	83	Missense	distal	7	no	10.997	11.065	EPSD	TCGA;ICGC;COSMIC	6.466	Up-regulation
TK_EGFR_EGFR_Y	Q8TDY4	ASAP3	P00533	EGFR	Y76	R77Q	77	Missense	proximal	1	no	10.997	12.820	EPSD	TCGA;ICGC;COSMIC	6.466	Up-regulation
TK_EGFR_EGFR_Y	Q8TDY4	ASAP3	P00533	EGFR	Y535	R542C	542	Missense	distal	7	no	6.799	6.523	EPSD	TCGA;COSMIC;CCLE	6.466	Down-regulation
TK_EGFR_EGFR_Y	Q8TDY4	ASAP3	P00533	EGFR	Y843	Y843C	843	Missense	central	0	yes	10.611	0.000	EPSD	TCGA;COSMIC	6.466	Loss
TK_EGFR_EGFR_Y	Q8TDY4	ASAP3	P00533	EGFR	Y843	P845S	845	Missense	proximal	2	no	10.611	10.590	EPSD	TCGA;COSMIC	6.466	Down-regulation
TK_EGFR_EGFR_Y	Q8TDY4	ASAP3	P00533	EGFR	Y843	R847K	847	Missense	distal	4	no	10.611	10.461	EPSD	TCGA;COSMIC	6.466	Down-regulation
TK_EGFR_EGFR_Y	Q8TDY4	ASAP3	P00533	EGFR	Y843	V846I	846	Missense	distal	3	no	10.611	10.444	EPSD	TCGA;COSMIC	6.466	Down-regulation
TK_EGFR_EGFR_Y	Q8TDY4	ASAP3	P00533	EGFR	Y843	S840L	840	Missense	distal	-3	no	10.611	8.332	EPSD	TCGA;COSMIC	6.466	Down-regulation
TK_EGFR_EGFR_Y	Q14164	IKBKE	P00533	EGFR	Y153	T156A	156	Missense	distal	3	no	13.253	13.495	EPSD;PhosphoSitePlus	TCGA;ICGC	6.466	Up-regulation
TK_EGFR_EGFR_Y	Q14164	IKBKE	P00533	EGFR	Y153	A160S	160	Missense	distal	7	no	13.253	12.989	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	6.466	Down-regulation
TK_EGFR_EGFR_Y	Q3V6T2	CCDC88A	P00533	EGFR	Y758	E752K	752	Missense	distal	-6	no	8.329	8.295	EPSD	TCGA;ICGC;COSMIC	6.466	Down-regulation
TK_EGFR_EGFR_Y	Q3V6T2	CCDC88A	P00533	EGFR	Y758	E764D	764	Missense	distal	6	no	8.329	7.752	EPSD	TCGA;ICGC;COSMIC	6.466	Down-regulation
TK_EGFR_EGFR_Y	Q3V6T2	CCDC88A	P00533	EGFR	Y758	R753C	753	Missense	distal	-5	no	8.329	8.147	EPSD	TCGA;ICGC;COSMIC	6.466	Down-regulation
TK_EGFR_EGFR_Y	Q3V6T2	CCDC88A	P00533	EGFR	Y758	D762N	762	Missense	distal	4	no	8.329	7.808	EPSD	TCGA;ICGC	6.466	Down-regulation
TK_EGFR_EGFR_Y	Q3V6T2	CCDC88A	P00533	EGFR	Y1765	S1768Y	1768	Missense	distal	3	no	9.180	8.688	PhosphoSitePlus;EPSD	TCGA;COSMIC	6.466	Down-regulation
TK_EGFR_EGFR_Y	Q92952	KCNN1	P00533	EGFR	Y109	R105C	105	Missense	distal	-4	no	7.204	7.088	PhosphoSitePlus	TCGA;ICGC;COSMIC	6.466	Down-regulation
TK_EGFR_EGFR_Y	Q92952	KCNN1	P00533	EGFR	Y109	F113L	113	Missense	distal	4	no	7.204	7.166	PhosphoSitePlus	TCGA;ICGC;COSMIC	6.466	Down-regulation
TK_EGFR_EGFR_Y	Q92952	KCNN1	P00533	EGFR	Y109	Y109S	109	Missense	central	0	yes	7.204	0.000	PhosphoSitePlus	TCGA;ICGC	6.466	Loss
TK_EGFR_EGFR_Y	P37231	PPARG	P00533	EGFR	Y102	D96H	96	Missense	distal	-6	no	7.404	7.391	EPSD	TCGA;COSMIC	6.466	Down-regulation
TK_EGFR_EGFR_Y	Q9UKV8	AGO2	P00533	EGFR	Y393	V394I	394	Missense	proximal	1	no	8.879	7.215	PhosphoSitePlus	TCGA;ICGC;COSMIC	6.466	Down-regulation
TK_EGFR_EGFR_Y	Q9UKV8	AGO2	P00533	EGFR	Y393	I399V	399	Missense	distal	6	no	8.879	8.518	PhosphoSitePlus	TCGA;ICGC;COSMIC	6.466	Down-regulation
TK_EGFR_EGFR_Y	Q9UKV8	AGO2	P00533	EGFR	Y393	P392S	392	Missense	proximal	-1	no	8.879	8.830	PhosphoSitePlus	TCGA;ICGC;COSMIC	6.466	Down-regulation
TK_EGFR_EGFR_Y	Q9UKV8	AGO2	P00533	EGFR	Y749	C751F	751	Missense	proximal	2	no	9.529	9.885	EPSD	TCGA;ICGC;COSMIC	6.466	Up-regulation
TK_EGFR_EGFR_Y	Q9UKV8	AGO2	P00533	EGFR	Y749	E745K	745	Missense	distal	-4	no	9.529	7.417	EPSD	TCGA;ICGC	6.466	Down-regulation
STE_STE20_PAKA_PAK2_ST	Q53QZ3	ARHGAP15	Q13177	PAK2	S39	H35D	35	Missense	distal	-4	no	13.884	16.955	EPSD	TCGA;ICGC;COSMIC	14.606	Gain
STE_STE20_PAKA_PAK2_ST	Q53QZ3	ARHGAP15	Q13177	PAK2	S217	E214K	214	Missense	distal	-3	no	-3.110	15.904	EPSD	TCGA;ICGC;COSMIC	14.606	Gain
STE_STE20_PAKA_PAK2_ST	Q53QZ3	ARHGAP15	Q13177	PAK2	S233	S233Y	233	Missense	central	0	yes	18.208	0.000	EPSD	TCGA;ICGC;COSMIC	14.606	Loss
STE_STE20_PAKA_PAK2_ST	Q53QZ3	ARHGAP15	Q13177	PAK2	S233	R231I	231	Missense	proximal	-2	no	18.208	5.418	EPSD	TCGA;ICGC;COSMIC	14.606	Loss
STE_STE20_PAKA_PAK2_ST	Q53QZ3	ARHGAP15	Q13177	PAK2	S241	S243Y	243	Missense	proximal	2	no	19.522	24.715	EPSD	TCGA;ICGC;COSMIC	14.606	Up-regulation
STE_STE20_PAKA_PAK2_ST	Q53QZ3	ARHGAP15	Q13177	PAK2	S241	D244N	244	Missense	distal	3	no	19.522	16.182	EPSD	TCGA;ICGC;COSMIC;GDSC;CCLE	14.606	Down-regulation
STE_STE20_PAKA_PAK2_ST	Q53QZ3	ARHGAP15	Q13177	PAK2	S241	S241C	241	Missense	central	0	yes	19.522	0.000	EPSD	TCGA;ICGC;COSMIC	14.606	Loss
STE_STE20_PAKA_PAK2_ST	Q53QZ3	ARHGAP15	Q13177	PAK2	S241	D247N	247	Missense	distal	6	no	19.522	17.965	EPSD	TCGA;ICGC;COSMIC	14.606	Down-regulation
STE_STE20_PAKA_PAK2_ST	Q53QZ3	ARHGAP15	Q13177	PAK2	S343	D342N	342	Missense	proximal	-1	no	24.999	18.590	EPSD	TCGA	14.606	Down-regulation
STE_STE20_PAKA_PAK2_ST	Q53QZ3	ARHGAP15	Q13177	PAK2	S343	I348S	348	Missense	distal	5	no	24.999	26.330	EPSD	TCGA;ICGC;COSMIC	14.606	Up-regulation
STE_STE20_PAKA_PAK2_ST	Q53QZ3	ARHGAP15	Q13177	PAK2	S393	S393Y	393	Missense	central	0	yes	34.562	0.000	EPSD	TCGA;ICGC;COSMIC;GDSC;CCLE	14.606	Loss
STE_STE20_PAKA_PAK2_ST	Q53QZ3	ARHGAP15	Q13177	PAK2	S393	E389G	389	Missense	distal	-4	no	34.562	36.146	EPSD	TCGA;ICGC	14.606	Up-regulation
STE_STE20_PAKA_PAK2_ST	Q13177	PAK2	Q13177	PAK2	S19	P12A	12	Missense	distal	-7	no	28.410	28.354	EPSD	TCGA;ICGC;COSMIC	14.606	Down-regulation
STE_STE20_PAKA_PAK2_ST	Q13177	PAK2	Q13177	PAK2	S19	M18K	18	Missense	proximal	-1	no	28.410	25.230	EPSD	TCGA;ICGC;COSMIC	14.606	Down-regulation
STE_STE20_PAKA_PAK2_ST	Q13177	PAK2	Q13177	PAK2	S20	M18K	18	Missense	proximal	-2	no	32.118	30.492	EPSD	TCGA;ICGC;COSMIC	14.606	Down-regulation
STE_STE20_PAKA_PAK2_ST	Q13177	PAK2	Q13177	PAK2	S55	S58L	58	Missense	distal	3	no	27.164	29.908	EPSD	TCGA;ICGC;COSMIC	14.606	Up-regulation
STE_STE20_PAKA_PAK2_ST	Q13177	PAK2	Q13177	PAK2	S55	K48R	48	Missense	distal	-7	no	27.164	28.009	EPSD	TCGA;ICGC;COSMIC	14.606	Up-regulation
STE_STE20_PAKA_PAK2_ST	Q13177	PAK2	Q13177	PAK2	S78	R71W	71	Missense	distal	-7	no	13.852	15.592	EPSD	TCGA;ICGC;COSMIC	14.606	Gain
STE_STE20_PAKA_PAK2_ST	Q13177	PAK2	Q13177	PAK2	S141	Q137P	137	Missense	distal	-4	no	32.805	33.961	EPSD	TCGA;ICGC;COSMIC	14.606	Up-regulation
STE_STE20_PAKA_PAK2_ST	Q13177	PAK2	Q13177	PAK2	S141	L140P	140	Missense	proximal	-1	no	32.805	24.321	EPSD	TCGA;ICGC;COSMIC	14.606	Down-regulation
STE_STE20_PAKA_PAK2_ST	Q13177	PAK2	Q13177	PAK2	S141	Y139C	139	Missense	proximal	-2	no	32.805	30.252	EPSD	TCGA;ICGC;COSMIC	14.606	Down-regulation
STE_STE20_PAKA_PAK2_ST	Q13177	PAK2	Q13177	PAK2	S141	S141G	141	Missense	central	0	yes	32.805	0.000	EPSD	TCGA;ICGC;COSMIC	14.606	Loss
STE_STE20_PAKA_PAK2_ST	Q13177	PAK2	Q13177	PAK2	S141	P144H	144	Missense	distal	3	no	32.805	28.685	EPSD	TCGA;ICGC;COSMIC	14.606	Down-regulation
STE_STE20_PAKA_PAK2_ST	Q13177	PAK2	Q13177	PAK2	S141	P144L	144	Missense	distal	3	no	32.805	30.562	EPSD	TCGA;ICGC	14.606	Down-regulation
STE_STE20_PAKA_PAK2_ST	Q13177	PAK2	Q13177	PAK2	S192	R186L	186	Missense	distal	-6	no	30.965	27.500	EPSD	TCGA;ICGC;COSMIC	14.606	Down-regulation
STE_STE20_PAKA_PAK2_ST	Q13177	PAK2	Q13177	PAK2	S192	T190A	190	Missense	proximal	-2	no	30.965	21.253	EPSD	TCGA;ICGC;COSMIC	14.606	Down-regulation
STE_STE20_PAKA_PAK2_ST	Q13177	PAK2	Q13177	PAK2	S197	A204T	204	Missense	distal	7	no	23.729	24.712	EPSD	TCGA;ICGC;COSMIC	14.606	Up-regulation
STE_STE20_PAKA_PAK2_ST	Q13177	PAK2	Q13177	PAK2	S197	T190A	190	Missense	distal	-7	no	23.729	23.812	EPSD	TCGA;ICGC;COSMIC	14.606	Up-regulation
STE_STE20_PAKA_PAK2_ST	Q13177	PAK2	Q13177	PAK2	S401	R400P	400	Missense	proximal	-1	no	14.649	7.936	EPSD	TCGA;ICGC;COSMIC	14.606	Loss
STE_STE20_PAKA_PAK2_ST	Q13177	PAK2	Q13177	PAK2	S401	R400H	400	Missense	proximal	-1	no	14.649	9.288	EPSD	TCGA;ICGC;COSMIC	14.606	Loss
STE_STE20_PAKA_PAK2_ST	Q13177	PAK2	Q13177	PAK2	S401	E396G	396	Missense	distal	-5	no	14.649	15.695	EPSD	TCGA;ICGC;COSMIC	14.606	Up-regulation
STE_STE20_PAKA_PAK2_ST	Q13177	PAK2	Q13177	PAK2	S401	R400C	400	Missense	proximal	-1	no	14.649	6.389	EPSD	TCGA;ICGC;COSMIC	14.606	Loss
STE_STE20_PAKA_PAK2_ST	Q13177	PAK2	Q13177	PAK2	T402	R400P	400	Missense	proximal	-2	no	35.000	25.675	PhosphoSitePlus	TCGA;ICGC;COSMIC	14.606	Down-regulation
STE_STE20_PAKA_PAK2_ST	Q13177	PAK2	Q13177	PAK2	T402	R400H	400	Missense	proximal	-2	no	35.000	30.043	PhosphoSitePlus	TCGA;ICGC;COSMIC	14.606	Down-regulation
STE_STE20_PAKA_PAK2_ST	Q13177	PAK2	Q13177	PAK2	T402	E396G	396	Missense	distal	-6	no	35.000	31.212	PhosphoSitePlus	TCGA;ICGC;COSMIC	14.606	Down-regulation
STE_STE20_PAKA_PAK2_ST	Q13177	PAK2	Q13177	PAK2	T402	R400C	400	Missense	proximal	-2	no	35.000	23.398	PhosphoSitePlus	TCGA;ICGC;COSMIC	14.606	Down-regulation
STE_STE20_PAKA_PAK2_ST	Q13177	PAK2	Q13177	PAK2	S490	E493Q	493	Missense	distal	3	no	22.155	21.246	EPSD	TCGA;ICGC;COSMIC	14.606	Down-regulation
STE_STE20_PAKA_PAK2_ST	Q13177	PAK2	Q13177	PAK2	S490	R488G	488	Missense	proximal	-2	no	22.155	2.827	EPSD	TCGA;ICGC;COSMIC;GDSC;CCLE	14.606	Loss
STE_STE20_PAKA_PAK2_ST	Q13177	PAK2	Q13177	PAK2	S490	S490L	490	Missense	central	0	yes	22.155	0.000	EPSD	TCGA;ICGC;COSMIC	14.606	Loss
STE_STE20_PAKA_PAK2_ST	Q13177	PAK2	Q13177	PAK2	S507	L509F	509	Missense	proximal	2	no	22.830	30.606	EPSD	TCGA;ICGC;COSMIC	14.606	Up-regulation
STE_STE20_PAKA_PAK2_ST	Q13177	PAK2	Q13177	PAK2	S507	M514I	514	Missense	distal	7	no	22.830	27.393	EPSD	TCGA;ICGC;COSMIC	14.606	Up-regulation
STE_STE20_PAKA_PAK2_ST	Q13177	PAK2	Q13177	PAK2	S507	P505L	505	Missense	proximal	-2	no	22.830	13.287	EPSD	TCGA;ICGC;COSMIC	14.606	Loss
STE_STE20_PAKA_PAK2_ST	Q13177	PAK2	Q13177	PAK2	S507	A503V	503	Missense	distal	-4	no	22.830	24.238	EPSD	TCGA;ICGC;COSMIC	14.606	Up-regulation
STE_STE20_PAKA_PAK2_ST	P05412	JUN	Q13177	PAK2	T8	F9L	9	Missense	proximal	1	no	19.613	18.019	PhosphoSitePlus;EPSD	TCGA;ICGC;COSMIC	14.606	Down-regulation
STE_STE20_PAKA_PAK2_ST	P05412	JUN	Q13177	PAK2	T8	A13D	13	Missense	distal	5	no	19.613	17.608	PhosphoSitePlus;EPSD	TCGA;ICGC;COSMIC	14.606	Down-regulation
STE_STE20_PAKA_PAK2_ST	P05412	JUN	Q13177	PAK2	T8	N15I	15	Missense	distal	7	no	19.613	18.904	PhosphoSitePlus;EPSD	TCGA;ICGC;COSMIC	14.606	Down-regulation
STE_STE20_PAKA_PAK2_ST	P05412	JUN	Q13177	PAK2	T8	E6K	6	Missense	proximal	-2	no	19.613	23.147	PhosphoSitePlus;EPSD	TCGA;ICGC	14.606	Up-regulation
STE_STE20_PAKA_PAK2_ST	P05412	JUN	Q13177	PAK2	S37	S37I	37	Missense	central	0	yes	16.937	0.000	EPSD	TCGA;ICGC;COSMIC	14.606	Loss
STE_STE20_PAKA_PAK2_ST	P05412	JUN	Q13177	PAK2	S37	L40M	40	Missense	distal	3	no	16.937	15.848	EPSD	TCGA;ICGC;COSMIC	14.606	Down-regulation
STE_STE20_PAKA_PAK2_ST	P05412	JUN	Q13177	PAK2	T89	G86W	86	Missense	distal	-3	no	33.388	19.716	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	14.606	Down-regulation
STE_STE20_PAKA_PAK2_ST	P05412	JUN	Q13177	PAK2	T93	G86W	86	Missense	distal	-7	no	24.978	25.718	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	14.606	Up-regulation
STE_STE20_PAKA_PAK2_ST	P05412	JUN	Q13177	PAK2	T93	C99Y	99	Missense	distal	6	no	24.978	24.903	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	14.606	Down-regulation
STE_STE20_PAKA_PAK2_ST	P05412	JUN	Q13177	PAK2	S243	P244L	244	Missense	proximal	1	no	17.257	18.598	EPSD	TCGA;ICGC;COSMIC	14.606	Up-regulation
STE_STE20_PAKA_PAK2_ST	P05412	JUN	Q13177	PAK2	T286	Q290H	290	Missense	distal	4	no	28.963	28.094	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	14.606	Down-regulation
STE_STE20_PAKA_PAK2_ST	P05412	JUN	Q13177	PAK2	T286	K283N	283	Missense	distal	-3	no	28.963	14.852	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	14.606	Down-regulation
STE_STE20_PAKA_PAK2_ST	P01106	MYC	Q13177	PAK2	S337	K341R	341	Missense	distal	4	no	24.946	24.475	EPSD	TCGA;ICGC;COSMIC	14.606	Down-regulation
STE_STE20_PAKA_PAK2_ST	P49023	PXN	Q13177	PAK2	S19	R21W	21	Missense	proximal	2	no	8.753	15.825	EPSD	TCGA	14.606	Gain
STE_STE20_PAKA_PAK2_ST	P49023	PXN	Q13177	PAK2	S126	Q124H	124	Missense	proximal	-2	no	8.721	16.674	EPSD	TCGA;COSMIC	14.606	Gain
STE_STE20_PAKA_PAK2_ST	P49023	PXN	Q13177	PAK2	S135	M134I	134	Missense	proximal	-1	no	23.779	16.768	EPSD	TCGA;COSMIC	14.606	Down-regulation
STE_STE20_PAKA_PAK2_ST	P49023	PXN	Q13177	PAK2	S135	L138M	138	Missense	distal	3	no	23.779	22.690	EPSD	TCGA;COSMIC	14.606	Down-regulation
STE_STE20_PAKA_PAK2_ST	P49023	PXN	Q13177	PAK2	S135	E128K	128	Missense	distal	-7	no	23.779	22.749	EPSD	TCGA;COSMIC	14.606	Down-regulation
STE_STE20_PAKA_PAK2_ST	P49023	PXN	Q13177	PAK2	S230	S227F	227	Missense	distal	-3	no	19.331	-6.758	EPSD	TCGA;COSMIC	14.606	Loss
STE_STE20_PAKA_PAK2_ST	P49023	PXN	Q13177	PAK2	S230	V237A	237	Missense	distal	7	no	19.331	15.991	EPSD	TCGA	14.606	Down-regulation
STE_STE20_PAKA_PAK2_ST	P49023	PXN	Q13177	PAK2	S243	V237A	237	Missense	distal	-6	no	12.903	16.021	EPSD	TCGA	14.606	Gain
STE_STE20_PAKA_PAK2_ST	P49023	PXN	Q13177	PAK2	S272	E268K	268	Missense	distal	-4	no	29.251	29.204	PhosphoSitePlus;EPSD	TCGA;COSMIC	14.606	Down-regulation
STE_STE20_PAKA_PAK2_ST	P49023	PXN	Q13177	PAK2	S272	S274L	274	Missense	proximal	2	no	29.251	25.548	PhosphoSitePlus;EPSD	TCGA;COSMIC	14.606	Down-regulation
STE_STE20_PAKA_PAK2_ST	P49023	PXN	Q13177	PAK2	S274	E268K	268	Missense	distal	-6	no	31.516	30.770	EPSD;PhosphoSitePlus	TCGA;COSMIC	14.606	Down-regulation
STE_STE20_PAKA_PAK2_ST	P49023	PXN	Q13177	PAK2	S274	S274L	274	Missense	central	0	yes	31.516	0.000	EPSD;PhosphoSitePlus	TCGA;COSMIC	14.606	Loss
STE_STE20_PAKA_PAK2_ST	Q05682	CALD1	Q13177	PAK2	T83	E78K	78	Missense	distal	-5	no	20.183	21.560	EPSD	TCGA;COSMIC	14.606	Up-regulation
STE_STE20_PAKA_PAK2_ST	Q05682	CALD1	Q13177	PAK2	T86	D92Y	92	Missense	distal	6	no	23.975	23.440	EPSD	TCGA;COSMIC	14.606	Down-regulation
STE_STE20_PAKA_PAK2_ST	Q05682	CALD1	Q13177	PAK2	S129	I125M	125	Missense	distal	-4	no	17.725	16.415	EPSD	TCGA	14.606	Down-regulation
STE_STE20_PAKA_PAK2_ST	Q05682	CALD1	Q13177	PAK2	S171	Y172H	172	Missense	proximal	1	no	19.578	18.430	EPSD	TCGA;COSMIC	14.606	Down-regulation
STE_STE20_PAKA_PAK2_ST	Q05682	CALD1	Q13177	PAK2	S480	V478G	478	Missense	proximal	-2	no	20.328	11.987	EPSD	TCGA;COSMIC	14.606	Loss
STE_STE20_PAKA_PAK2_ST	Q05682	CALD1	Q13177	PAK2	S480	K485N	485	Missense	distal	5	no	20.328	20.520	EPSD	TCGA;COSMIC	14.606	Up-regulation
STE_STE20_PAKA_PAK2_ST	Q05682	CALD1	Q13177	PAK2	T509	T506A	506	Missense	distal	-3	no	12.812	16.563	EPSD	TCGA;COSMIC	14.606	Gain
STE_STE20_PAKA_PAK2_ST	Q05682	CALD1	Q13177	PAK2	S518	V519M	519	Missense	proximal	1	no	15.654	16.561	EPSD	TCGA;COSMIC	14.606	Up-regulation
STE_STE20_PAKA_PAK2_ST	Q05682	CALD1	Q13177	PAK2	S518	P513R	513	Missense	distal	-5	no	15.654	12.674	EPSD	TCGA;COSMIC	14.606	Loss
STE_STE20_PAKA_PAK2_ST	Q05682	CALD1	Q13177	PAK2	S518	P513S	513	Missense	distal	-5	no	15.654	14.743	EPSD	TCGA;COSMIC	14.606	Down-regulation
STE_STE20_PAKA_PAK2_ST	Q05682	CALD1	Q13177	PAK2	S518	S518I	518	Missense	central	0	yes	15.654	0.000	EPSD	TCGA;COSMIC	14.606	Loss
STE_STE20_PAKA_PAK2_ST	Q05682	CALD1	Q13177	PAK2	S642	S643F	643	Missense	proximal	1	no	14.303	14.916	EPSD	TCGA;COSMIC	14.606	Gain
STE_STE20_PAKA_PAK2_ST	Q05682	CALD1	Q13177	PAK2	S665	S665L	665	Missense	central	0	yes	15.524	0.000	EPSD	TCGA;COSMIC	14.606	Loss
STE_STE20_PAKA_PAK2_ST	Q05682	CALD1	Q13177	PAK2	S665	S660R	660	Missense	distal	-5	no	15.524	13.455	EPSD	TCGA;COSMIC	14.606	Loss
STE_STE20_PAKA_PAK2_ST	Q05682	CALD1	Q13177	PAK2	S665	V663G	663	Missense	proximal	-2	no	15.524	7.182	EPSD	TCGA;COSMIC	14.606	Loss
STE_STE20_PAKA_PAK2_ST	Q05682	CALD1	Q13177	PAK2	S665	Q668K	668	Missense	distal	3	no	15.524	15.032	EPSD	TCGA;COSMIC	14.606	Down-regulation
STE_STE20_PAKA_PAK2_ST	Q05682	CALD1	Q13177	PAK2	S714	V709I	709	Missense	distal	-5	no	30.407	31.860	EPSD;PhosphoSitePlus	TCGA	14.606	Up-regulation
STE_STE20_PAKA_PAK2_ST	Q05682	CALD1	Q13177	PAK2	S744	S743Y	743	Missense	proximal	-1	no	29.070	26.282	PhosphoSitePlus;EPSD	TCGA;COSMIC	14.606	Down-regulation
STE_STE20_PAKA_PAK2_ST	Q16659	MAPK6	Q13177	PAK2	S386	D387Y	387	Missense	proximal	1	no	11.693	15.936	EPSD	TCGA;ICGC;COSMIC	14.606	Gain
STE_STE20_PAKA_PAK2_ST	Q16659	MAPK6	Q13177	PAK2	S450	N456D	456	Missense	distal	6	no	20.229	21.786	EPSD	TCGA;ICGC;COSMIC	14.606	Up-regulation
STE_STE20_PAKA_PAK2_ST	Q16659	MAPK6	Q13177	PAK2	S451	N456D	456	Missense	distal	5	no	25.098	22.977	EPSD	TCGA;ICGC;COSMIC	14.606	Down-regulation
STE_STE20_PAKA_PAK2_ST	P00519	ABL1	Q13177	PAK2	S618	S620G	620	Missense	proximal	2	no	28.019	20.650	EPSD;PhosphoSitePlus	TCGA;COSMIC	14.606	Down-regulation
STE_STE20_PAKA_PAK2_ST	P00519	ABL1	Q13177	PAK2	S618	S620R	620	Missense	proximal	2	no	28.019	20.721	EPSD;PhosphoSitePlus	TCGA;COSMIC	14.606	Down-regulation
STE_STE20_PAKA_PAK2_ST	P00519	ABL1	Q13177	PAK2	S619	S620G	620	Missense	proximal	1	no	51.499	47.537	PhosphoSitePlus;EPSD	TCGA;COSMIC	14.606	Down-regulation
STE_STE20_PAKA_PAK2_ST	P00519	ABL1	Q13177	PAK2	S619	S620R	620	Missense	proximal	1	no	51.499	47.118	PhosphoSitePlus;EPSD	TCGA;COSMIC	14.606	Down-regulation
STE_STE20_PAKA_PAK2_ST	P35240	NF2	Q13177	PAK2	T251	P246L	246	Missense	distal	-5	no	23.380	20.827	EPSD	TCGA;ICGC;COSMIC	14.606	Down-regulation
STE_STE20_PAKA_PAK2_ST	P35240	NF2	Q13177	PAK2	T251	R249K	249	Missense	proximal	-2	no	23.380	14.726	EPSD	TCGA;ICGC;COSMIC	14.606	Down-regulation
STE_STE20_PAKA_PAK2_ST	P35240	NF2	Q13177	PAK2	S255	R249K	249	Missense	distal	-6	no	24.681	23.180	EPSD	TCGA;ICGC;COSMIC	14.606	Down-regulation
STE_STE20_PAKA_PAK2_ST	P35240	NF2	Q13177	PAK2	S265	F271L	271	Missense	distal	6	no	26.682	25.928	EPSD	TCGA;ICGC	14.606	Down-regulation
STE_STE20_PAKA_PAK2_ST	P35240	NF2	Q13177	PAK2	T415	R418C	418	Missense	distal	3	no	16.554	15.485	EPSD	TCGA;ICGC;COSMIC;CCLE	14.606	Down-regulation
STE_STE20_PAKA_PAK2_ST	P35240	NF2	Q13177	PAK2	T415	R418H	418	Missense	distal	3	no	16.554	13.446	EPSD	TCGA;ICGC	14.606	Loss
STE_STE20_PAKA_PAK2_ST	P35240	NF2	Q13177	PAK2	T415	T419M	419	Missense	distal	4	no	16.554	13.575	EPSD	TCGA;ICGC	14.606	Loss
STE_STE20_PAKA_PAK2_ST	Q15796	SMAD2	Q13177	PAK2	T172	P176R	176	Missense	distal	4	no	19.293	18.496	EPSD	TCGA	14.606	Down-regulation
STE_STE20_PAKA_PAK2_ST	Q15796	SMAD2	Q13177	PAK2	S417	G421W	421	Missense	distal	4	no	32.504	29.416	PhosphoSitePlus	TCGA;ICGC;COSMIC	14.606	Down-regulation
STE_STE20_PAKA_PAK2_ST	Q15796	SMAD2	Q13177	PAK2	S417	G421A	421	Missense	distal	4	no	32.504	28.602	PhosphoSitePlus	TCGA;ICGC;COSMIC	14.606	Down-regulation
STE_STE20_PAKA_PAK2_ST	Q15796	SMAD2	Q13177	PAK2	S417	S417R	417	Missense	central	0	yes	32.504	0.000	PhosphoSitePlus	TCGA;ICGC	14.606	Loss
STE_STE20_PAKA_PAK2_ST	Q15796	SMAD2	Q13177	PAK2	T430	R428K	428	Missense	proximal	-2	no	25.015	16.362	EPSD	TCGA;ICGC;COSMIC	14.606	Down-regulation
STE_STE20_PAKA_PAK2_ST	Q15796	SMAD2	Q13177	PAK2	T430	S433G	433	Missense	distal	3	no	25.015	30.347	EPSD	TCGA;ICGC;COSMIC	14.606	Up-regulation
STE_STE20_PAKA_PAK2_ST	Q04637	EIF4G1	Q13177	PAK2	S1092	G1096W	1096	Missense	distal	4	no	28.254	25.167	EPSD	TCGA;COSMIC	14.606	Down-regulation
STE_STE20_PAKA_PAK2_ST	Q04637	EIF4G1	Q13177	PAK2	S1097	G1096W	1096	Missense	proximal	-1	no	14.282	15.124	EPSD	TCGA;COSMIC	14.606	Gain
STE_STE20_PAKA_PAK2_ST	Q04637	EIF4G1	Q13177	PAK2	S1098	G1096W	1096	Missense	proximal	-2	no	16.332	5.735	EPSD	TCGA;COSMIC	14.606	Loss
STE_STE20_PAKA_PAK2_ST	Q70Z35	PREX2	Q13177	PAK2	T374	Q372H	372	Missense	proximal	-2	no	8.689	16.641	EPSD	TCGA;ICGC;COSMIC	14.606	Gain
STE_STE20_PAKA_PAK2_ST	Q70Z35	PREX2	Q13177	PAK2	S1052	Q1046E	1046	Missense	distal	-6	no	15.309	17.666	EPSD	TCGA	14.606	Up-regulation
STE_STE20_PAKA_PAK2_ST	Q70Z35	PREX2	Q13177	PAK2	S1052	I1047R	1047	Missense	distal	-5	no	15.309	12.619	EPSD	TCGA;ICGC;COSMIC	14.606	Loss
STE_STE20_PAKA_PAK2_ST	Q70Z35	PREX2	Q13177	PAK2	S1052	D1048V	1048	Missense	distal	-4	no	15.309	14.356	EPSD	TCGA;ICGC;COSMIC	14.606	Loss
STE_STE20_PAKA_PAK2_ST	Q70Z35	PREX2	Q13177	PAK2	S1052	D1048H	1048	Missense	distal	-4	no	15.309	12.239	EPSD	TCGA;ICGC;COSMIC	14.606	Loss
STE_STE20_PAKA_PAK2_ST	Q70Z35	PREX2	Q13177	PAK2	S1052	I1047T	1047	Missense	distal	-5	no	15.309	15.999	EPSD	TCGA;ICGC;COSMIC	14.606	Up-regulation
STE_STE20_PAKA_PAK2_ST	Q70Z35	PREX2	Q13177	PAK2	S1052	S1053L	1053	Missense	proximal	1	no	15.309	14.329	EPSD	TCGA;ICGC;COSMIC	14.606	Loss
STE_STE20_PAKA_PAK2_ST	Q70Z35	PREX2	Q13177	PAK2	T1064	E1061K	1061	Missense	distal	-3	no	4.243	23.257	EPSD	TCGA;ICGC;COSMIC	14.606	Gain
STE_STE20_PAKA_PAK2_ST	Q70Z35	PREX2	Q13177	PAK2	S1065	R1062C	1062	Missense	distal	-3	no	23.060	5.879	EPSD	TCGA;ICGC;COSMIC	14.606	Loss
STE_STE20_PAKA_PAK2_ST	Q70Z35	PREX2	Q13177	PAK2	S1065	E1061K	1061	Missense	distal	-4	no	23.060	23.013	EPSD	TCGA;ICGC;COSMIC	14.606	Down-regulation
STE_STE20_PAKA_PAK2_ST	Q70Z35	PREX2	Q13177	PAK2	S1065	P1070L	1070	Missense	distal	5	no	23.060	26.087	EPSD	TCGA;ICGC;COSMIC	14.606	Up-regulation
STE_STE20_PAKA_PAK2_ST	Q70Z35	PREX2	Q13177	PAK2	S1065	L1060V	1060	Missense	distal	-5	no	23.060	23.870	EPSD	TCGA;ICGC	14.606	Up-regulation
STE_STE20_PAKA_PAK2_ST	Q70Z35	PREX2	Q13177	PAK2	S1107	N1112K	1112	Missense	distal	5	no	36.962	36.770	PhosphoSitePlus	TCGA;ICGC;COSMIC	14.606	Down-regulation
STE_STE20_PAKA_PAK2_ST	Q70Z35	PREX2	Q13177	PAK2	S1107	D1110Y	1110	Missense	distal	3	no	36.962	30.309	PhosphoSitePlus	TCGA;ICGC;COSMIC	14.606	Down-regulation
STE_STE20_PAKA_PAK2_ST	Q8IYU2	HACE1	Q13177	PAK2	T33	A40T	40	Missense	distal	7	no	17.289	18.272	EPSD	TCGA;ICGC;COSMIC	14.606	Up-regulation
STE_STE20_PAKA_PAK2_ST	Q8IYU2	HACE1	Q13177	PAK2	T33	P36L	36	Missense	distal	3	no	17.289	15.047	EPSD	TCGA;ICGC;COSMIC	14.606	Down-regulation
STE_STE20_PAKA_PAK2_ST	Q8IYU2	HACE1	Q13177	PAK2	S385	K380N	380	Missense	distal	-5	no	35.489	34.616	PhosphoSitePlus	TCGA;ICGC;COSMIC	14.606	Down-regulation
CMGC_MAPK_ERK7_MAPK15_ST	Q8TD08	MAPK15	Q8TD08	MAPK15	T175	D171N	171	Missense	distal	-4	no	10.983	11.005	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	5.395	Up-regulation
CMGC_MAPK_ERK7_MAPK15_ST	Q8TD08	MAPK15	Q8TD08	MAPK15	S192	A185S	185	Missense	distal	-7	no	10.763	10.940	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	5.395	Up-regulation
CMGC_MAPK_ERK7_MAPK15_ST	Q8TD08	MAPK15	Q8TD08	MAPK15	S192	A185V	185	Missense	distal	-7	no	10.763	10.509	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	5.395	Down-regulation
CMGC_MAPK_ERK7_MAPK15_ST	Q8TD08	MAPK15	Q8TD08	MAPK15	S192	V188L	188	Missense	distal	-4	no	10.763	10.845	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	5.395	Up-regulation
CMGC_MAPK_ERK7_MAPK15_ST	Q8TD08	MAPK15	Q8TD08	MAPK15	S192	S192L	192	Missense	central	0	yes	10.763	0.000	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC;CCLE	5.395	Loss
CMGC_MAPK_ERK7_MAPK15_ST	Q8TD08	MAPK15	Q8TD08	MAPK15	S331	E334Q	334	Missense	distal	3	no	11.674	11.449	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	5.395	Down-regulation
CMGC_MAPK_ERK7_MAPK15_ST	Q8TD08	MAPK15	Q8TD08	MAPK15	S331	E326K	326	Missense	distal	-5	no	11.674	10.055	EPSD;PhosphoSitePlus	TCGA;ICGC	5.395	Down-regulation
CMGC_MAPK_ERK7_MAPK15_ST	Q8TD08	MAPK15	Q8TD08	MAPK15	T352	G347V	347	Missense	distal	-5	no	9.993	9.621	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	5.395	Down-regulation
CMGC_MAPK_ERK7_MAPK15_ST	Q8TD08	MAPK15	Q8TD08	MAPK15	T352	E359D	359	Missense	distal	7	no	9.993	10.479	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	5.395	Up-regulation
CMGC_MAPK_ERK7_MAPK15_ST	Q8TD08	MAPK15	Q8TD08	MAPK15	S362	E359D	359	Missense	distal	-3	no	9.448	9.599	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	5.395	Up-regulation
CMGC_MAPK_ERK7_MAPK15_ST	Q8TD08	MAPK15	Q8TD08	MAPK15	S379	P378S	378	Missense	proximal	-1	no	10.779	10.567	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	5.395	Down-regulation
CMGC_MAPK_ERK7_MAPK15_ST	Q8TD08	MAPK15	Q8TD08	MAPK15	S379	D374N	374	Missense	distal	-5	no	10.779	9.818	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	5.395	Down-regulation
CMGC_MAPK_ERK7_MAPK15_ST	Q8TD08	MAPK15	Q8TD08	MAPK15	T381	P378S	378	Missense	distal	-3	no	10.411	10.279	PhosphoSitePlus;EPSD	TCGA;ICGC;COSMIC	5.395	Down-regulation
CMGC_MAPK_ERK7_MAPK15_ST	Q8TD08	MAPK15	Q8TD08	MAPK15	T381	D374N	374	Missense	distal	-7	no	10.411	10.200	PhosphoSitePlus;EPSD	TCGA;ICGC;COSMIC	5.395	Down-regulation
CMGC_MAPK_ERK7_MAPK15_ST	P25963	NFKBIA	Q8TD08	MAPK15	S32	D31N	31	Missense	proximal	-1	no	9.810	9.778	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	5.395	Down-regulation
CMGC_MAPK_ERK7_MAPK15_ST	P25963	NFKBIA	Q8TD08	MAPK15	S32	D27H	27	Missense	distal	-5	no	9.810	8.591	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	5.395	Down-regulation
CMGC_MAPK_ERK7_MAPK15_ST	P25963	NFKBIA	Q8TD08	MAPK15	S36	E41K	41	Missense	distal	5	no	10.289	10.799	PhosphoSitePlus;EPSD	TCGA;ICGC	5.395	Up-regulation
CMGC_MAPK_ERK7_MAPK15_ST	P25963	NFKBIA	Q8TD08	MAPK15	S36	D31N	31	Missense	distal	-5	no	10.289	9.328	PhosphoSitePlus;EPSD	TCGA;ICGC;COSMIC	5.395	Down-regulation
CMGC_MAPK_ERK7_MAPK15_ST	P25963	NFKBIA	Q8TD08	MAPK15	S36	Y42C	42	Missense	distal	6	no	10.289	10.264	PhosphoSitePlus;EPSD	TCGA;ICGC;COSMIC	5.395	Down-regulation
CMGC_MAPK_ERK7_MAPK15_ST	P25963	NFKBIA	Q8TD08	MAPK15	S283	E282K	282	Missense	proximal	-1	no	5.408	5.915	EPSD	TCGA;COSMIC	5.395	Up-regulation
CMGC_MAPK_ERK7_MAPK15_ST	P25963	NFKBIA	Q8TD08	MAPK15	S283	D290G	290	Missense	distal	7	no	5.408	5.880	EPSD	TCGA	5.395	Up-regulation
CMGC_MAPK_ERK7_MAPK15_ST	P05412	JUN	Q8TD08	MAPK15	S73	S73L	73	Missense	central	0	yes	11.823	0.000	PhosphoSitePlus;EPSD	TCGA;ICGC;COSMIC	5.395	Loss
CMGC_MAPK_ERK7_MAPK15_ST	P05412	JUN	Q8TD08	MAPK15	T89	G86W	86	Missense	distal	-3	no	5.426	5.261	EPSD	TCGA;ICGC;COSMIC	5.395	Loss
CMGC_MAPK_ERK7_MAPK15_ST	P05412	JUN	Q8TD08	MAPK15	T239	P244L	244	Missense	distal	5	no	5.110	5.586	EPSD	TCGA;ICGC;COSMIC	5.395	Gain
TK_Ret_RET_Y	P27986	PIK3R1	P07949	RET	Y203	A201V	201	Missense	proximal	-2	no	52.559	51.291	PhosphoSitePlus	TCGA;ICGC	28.094	Down-regulation
TK_Ret_RET_Y	P27986	PIK3R1	P07949	RET	Y203	S204C	204	Missense	proximal	1	no	52.559	50.215	PhosphoSitePlus	TCGA;ICGC;COSMIC	28.094	Down-regulation
TK_Ret_RET_Y	P27986	PIK3R1	P07949	RET	Y203	S208Y	208	Missense	distal	5	no	52.559	51.851	PhosphoSitePlus	TCGA;ICGC;COSMIC	28.094	Down-regulation
TK_Ret_RET_Y	P27986	PIK3R1	P07949	RET	Y203	P196H	196	Missense	distal	-7	no	52.559	48.219	PhosphoSitePlus	TCGA;ICGC	28.094	Down-regulation
TK_Ret_RET_Y	P27986	PIK3R1	P07949	RET	Y203	V202I	202	Missense	proximal	-1	no	52.559	52.750	PhosphoSitePlus	TCGA;ICGC;COSMIC	28.094	Up-regulation
TK_Ret_RET_Y	P07949	RET	P07949	RET	Y687	R693C	693	Missense	distal	6	no	50.930	50.808	EPSD;PhosphoSitePlus	TCGA;ICGC	28.094	Down-regulation
TK_Ret_RET_Y	P07949	RET	P07949	RET	Y687	V685I	685	Missense	proximal	-2	no	50.930	46.420	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC;CCLE	28.094	Down-regulation
TK_Ret_RET_Y	P07949	RET	P07949	RET	Y806	R813W	813	Missense	distal	7	no	31.198	25.482	EPSD;PhosphoSitePlus	TCGA;ICGC	28.094	Loss
TK_Ret_RET_Y	P07949	RET	P07949	RET	Y806	A807T	807	Missense	proximal	1	no	31.198	29.763	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	28.094	Down-regulation
TK_Ret_RET_Y	P07949	RET	P07949	RET	Y809	R813W	813	Missense	distal	4	no	39.481	37.552	EPSD;PhosphoSitePlus	TCGA;ICGC	28.094	Down-regulation
TK_Ret_RET_Y	P07949	RET	P07949	RET	Y809	A807T	807	Missense	proximal	-2	no	39.481	38.903	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	28.094	Down-regulation
TK_Ret_RET_Y	P07949	RET	P07949	RET	Y826	G823E	823	Missense	distal	-3	no	41.269	43.017	PhosphoSitePlus;EPSD	TCGA;ICGC;COSMIC	28.094	Up-regulation
TK_Ret_RET_Y	P07949	RET	P07949	RET	Y826	R820H	820	Missense	distal	-6	no	41.269	41.240	PhosphoSitePlus;EPSD	TCGA;ICGC;COSMIC	28.094	Down-regulation
TK_Ret_RET_Y	P07949	RET	P07949	RET	Y900	E901K	901	Missense	proximal	1	no	36.527	36.448	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	28.094	Down-regulation
TK_Ret_RET_Y	P07949	RET	P07949	RET	Y900	G894S	894	Missense	distal	-6	no	36.527	36.599	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	28.094	Up-regulation
TK_Ret_RET_Y	P07949	RET	P07949	RET	Y900	K907T	907	Missense	distal	7	no	36.527	40.244	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	28.094	Up-regulation
TK_Ret_RET_Y	P07949	RET	P07949	RET	Y905	E901K	901	Missense	distal	-4	no	53.485	52.816	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	28.094	Down-regulation
TK_Ret_RET_Y	P07949	RET	P07949	RET	Y905	R912W	912	Missense	distal	7	no	53.485	47.769	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	28.094	Down-regulation
TK_Ret_RET_Y	P07949	RET	P07949	RET	Y905	R912Q	912	Missense	distal	7	no	53.485	43.215	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	28.094	Down-regulation
TK_Ret_RET_Y	P07949	RET	P07949	RET	Y905	K907T	907	Missense	proximal	2	no	53.485	52.953	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	28.094	Down-regulation
TK_Ret_RET_Y	P07949	RET	P07949	RET	Y981	E979Q	979	Missense	proximal	-2	no	39.068	34.759	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	28.094	Down-regulation
TK_Ret_RET_Y	P07949	RET	P07949	RET	Y981	C976Y	976	Missense	distal	-5	no	39.068	38.731	EPSD;PhosphoSitePlus	TCGA;ICGC	28.094	Down-regulation
TK_Ret_RET_Y	P07949	RET	P07949	RET	Y981	R982H	982	Missense	proximal	1	no	39.068	38.350	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	28.094	Down-regulation
TK_Ret_RET_Y	P07949	RET	P07949	RET	Y1015	M1009V	1009	Missense	distal	-6	no	48.606	48.594	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	28.094	Down-regulation
TK_Ret_RET_Y	P07949	RET	P07949	RET	Y1015	A1019V	1019	Missense	distal	4	no	48.606	47.446	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	28.094	Down-regulation
TK_Ret_RET_Y	P07949	RET	P07949	RET	Y1015	L1018I	1018	Missense	distal	3	no	48.606	47.355	EPSD;PhosphoSitePlus	TCGA;ICGC	28.094	Down-regulation
TK_Ret_RET_Y	P07949	RET	P07949	RET	Y1029	G1032D	1032	Missense	distal	3	no	38.638	39.917	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	28.094	Up-regulation
TK_Ret_RET_Y	P07949	RET	P07949	RET	Y1062	N1059D	1059	Missense	distal	-3	no	59.960	60.147	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	28.094	Up-regulation
TK_Ret_RET_Y	P07949	RET	P07949	RET	Y1090	D1093G	1093	Missense	distal	3	no	37.417	36.138	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	28.094	Down-regulation
TK_Ret_RET_Y	P07949	RET	P07949	RET	Y1090	D1093N	1093	Missense	distal	3	no	37.417	36.914	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	28.094	Down-regulation
TK_Ret_RET_Y	P07949	RET	P07949	RET	Y1090	N1092H	1092	Missense	proximal	2	no	37.417	37.090	EPSD;PhosphoSitePlus	TCGA;ICGC	28.094	Down-regulation
TK_Ret_RET_Y	P07949	RET	P07949	RET	Y1096	L1101V	1101	Missense	distal	5	no	59.110	59.357	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC;GDSC;CCLE	28.094	Up-regulation
TK_Ret_RET_Y	P07949	RET	P07949	RET	Y1096	D1093G	1093	Missense	distal	-3	no	59.110	57.467	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	28.094	Down-regulation
TK_Ret_RET_Y	P07949	RET	P07949	RET	Y1096	D1093N	1093	Missense	distal	-3	no	59.110	58.922	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	28.094	Down-regulation
TK_Ret_RET_Y	P07949	RET	P07949	RET	Y1096	N1092H	1092	Missense	distal	-4	no	59.110	53.733	EPSD;PhosphoSitePlus	TCGA;ICGC	28.094	Down-regulation
TK_Ret_RET_Y	O15530	PDPK1	P07949	RET	Y248	V249I	249	Missense	proximal	1	no	37.834	35.624	EPSD	TCGA;COSMIC	28.094	Down-regulation
TK_Ret_RET_Y	O15530	PDPK1	P07949	RET	Y415	G409S	409	Missense	distal	-6	no	37.150	37.222	EPSD	TCGA;COSMIC	28.094	Up-regulation
TK_Ret_RET_Y	Q99704	DOK1	P07949	RET	Y315	S310F	310	Missense	distal	-5	no	32.697	30.994	EPSD	TCGA;COSMIC	28.094	Down-regulation
TK_Ret_RET_Y	Q99704	DOK1	P07949	RET	Y315	D317N	317	Missense	proximal	2	no	32.697	32.292	EPSD	TCGA;COSMIC	28.094	Down-regulation
TK_Ret_RET_Y	Q99704	DOK1	P07949	RET	Y315	P318S	318	Missense	distal	3	no	32.697	32.562	EPSD	TCGA;ICGC	28.094	Down-regulation
TK_Ret_RET_Y	Q99704	DOK1	P07949	RET	Y398	P404L	404	Missense	distal	6	no	52.200	51.504	PhosphoSitePlus	TCGA;COSMIC	28.094	Down-regulation
TK_Ret_RET_Y	Q99704	DOK1	P07949	RET	Y409	P404L	404	Missense	distal	-5	no	29.158	28.853	EPSD	TCGA;COSMIC	28.094	Down-regulation
TK_Ret_RET_Y	Q05397	PTK2	P07949	RET	Y861	I860M	860	Missense	proximal	-1	no	43.327	43.171	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	28.094	Down-regulation
TK_Ret_RET_Y	Q05397	PTK2	P07949	RET	Y861	P867S	867	Missense	distal	6	no	43.327	43.765	EPSD;PhosphoSitePlus	TCGA;ICGC	28.094	Up-regulation
TK_Ret_RET_Y	Q05397	PTK2	P07949	RET	Y861	H859R	859	Missense	proximal	-2	no	43.327	47.115	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	28.094	Up-regulation
TK_Ret_RET_Y	P19174	PLCG1	P07949	RET	Y93	R92G	92	Missense	proximal	-1	no	30.815	30.885	EPSD	TCGA;ICGC;COSMIC	28.094	Up-regulation
TK_Ret_RET_Y	P19174	PLCG1	P07949	RET	Y93	R88Q	88	Missense	distal	-5	no	30.815	30.367	EPSD	TCGA;ICGC;COSMIC	28.094	Down-regulation
TK_Ret_RET_Y	P19174	PLCG1	P07949	RET	Y669	E664K	664	Missense	distal	-5	no	39.231	39.360	EPSD	TCGA;ICGC;COSMIC	28.094	Up-regulation
TK_Ret_RET_Y	P19174	PLCG1	P07949	RET	Y771	A767P	767	Missense	distal	-4	no	29.084	32.066	EPSD	TCGA;ICGC;COSMIC	28.094	Up-regulation
TK_Ret_RET_Y	P19174	PLCG1	P07949	RET	Y771	R778C	778	Missense	distal	7	no	29.084	20.730	EPSD	TCGA;ICGC;COSMIC;GDSC;CCLE	28.094	Loss
TK_Ret_RET_Y	P19174	PLCG1	P07949	RET	Y783	F782L	782	Missense	proximal	-1	no	51.128	51.015	PhosphoSitePlus	TCGA;ICGC;COSMIC	28.094	Down-regulation
TK_Ret_RET_Y	P19174	PLCG1	P07949	RET	Y783	P788H	788	Missense	distal	5	no	51.128	50.646	PhosphoSitePlus	TCGA;ICGC	28.094	Down-regulation
TK_Ret_RET_Y	P19174	PLCG1	P07949	RET	Y783	R778C	778	Missense	distal	-5	no	51.128	50.788	PhosphoSitePlus	TCGA;ICGC;COSMIC;GDSC;CCLE	28.094	Down-regulation
TK_Ret_RET_Y	Q8N4X5	AFAP1L2	P07949	RET	Y54	E53D	53	Missense	proximal	-1	no	39.951	39.924	PhosphoSitePlus	TCGA;ICGC;COSMIC	28.094	Down-regulation
TK_Ret_RET_Y	Q8N4X5	AFAP1L2	P07949	RET	Y54	T61N	61	Missense	distal	7	no	39.951	33.810	PhosphoSitePlus	TCGA;ICGC;COSMIC	28.094	Down-regulation
TK_Ret_RET_Y	Q8N4X5	AFAP1L2	P07949	RET	Y124	G122S	122	Missense	proximal	-2	no	30.292	33.983	EPSD	TCGA;ICGC	28.094	Up-regulation
TK_Ret_RET_Y	Q8N4X5	AFAP1L2	P07949	RET	Y413	S414F	414	Missense	proximal	1	no	30.679	27.217	EPSD	TCGA;COSMIC	28.094	Loss
TK_Ret_RET_Y	Q8N4X5	AFAP1L2	P07949	RET	Y413	P407L	407	Missense	distal	-6	no	30.679	30.670	EPSD	TCGA;ICGC;COSMIC	28.094	Down-regulation
TK_Ret_RET_Y	Q8N4X5	AFAP1L2	P07949	RET	Y457	E454K	454	Missense	distal	-3	no	38.835	38.872	EPSD	TCGA;ICGC;COSMIC	28.094	Up-regulation
TK_Ret_RET_Y	Q8N4X5	AFAP1L2	P07949	RET	Y457	D463N	463	Missense	distal	6	no	38.835	39.252	EPSD	TCGA;ICGC;COSMIC	28.094	Up-regulation
TK_Ret_RET_Y	Q8N4X5	AFAP1L2	P07949	RET	Y537	R535Q	535	Missense	proximal	-2	no	36.315	31.372	EPSD	TCGA;COSMIC	28.094	Down-regulation
TK_Ret_RET_Y	Q8N4X5	AFAP1L2	P07949	RET	Y668	A663T	663	Missense	distal	-5	no	34.635	33.766	EPSD	TCGA;ICGC;COSMIC	28.094	Down-regulation
TK_Ret_RET_Y	P45984	MAPK9	P07949	RET	Y185	M181I	181	Missense	distal	-4	no	56.127	49.836	PhosphoSitePlus	TCGA;ICGC;COSMIC	28.094	Down-regulation
TK_Ret_RET_Y	P45984	MAPK9	P07949	RET	Y185	T183A	183	Missense	proximal	-2	no	56.127	56.705	PhosphoSitePlus	TCGA;ICGC;COSMIC	28.094	Up-regulation
TK_Ret_RET_Y	P31749	AKT1	P07949	RET	Y315	E322K	322	Missense	distal	7	no	39.688	40.448	PhosphoSitePlus	TCGA;ICGC;COSMIC	28.094	Up-regulation
TK_Ret_RET_Y	P31749	AKT1	P07949	RET	Y315	G311D	311	Missense	distal	-4	no	39.688	47.766	PhosphoSitePlus	TCGA;ICGC;COSMIC;GDSC;CCLE	28.094	Up-regulation
TK_Ret_RET_Y	P28482	MAPK1	P07949	RET	Y36	G34C	34	Missense	proximal	-2	no	32.135	32.122	EPSD	TCGA;ICGC;COSMIC;CCLE	28.094	Down-regulation
TK_Ret_RET_Y	P28482	MAPK1	P07949	RET	Y187	R191C	191	Missense	distal	4	no	57.218	55.058	PhosphoSitePlus	TCGA;ICGC;COSMIC	28.094	Down-regulation
TK_Ret_RET_Y	P28482	MAPK1	P07949	RET	Y187	R191H	191	Missense	distal	4	no	57.218	55.027	PhosphoSitePlus	TCGA;ICGC;COSMIC	28.094	Down-regulation
TK_Ret_RET_Y	P28482	MAPK1	P07949	RET	Y205	G204S	204	Missense	proximal	-1	no	35.107	34.920	EPSD	TCGA;ICGC	28.094	Down-regulation
TK_Ret_RET_Y	P45983	MAPK8	P07949	RET	Y185	T178M	178	Missense	distal	-7	no	57.788	53.692	PhosphoSitePlus	TCGA;ICGC;COSMIC	28.094	Down-regulation
TK_Ret_RET_Y	P45983	MAPK8	P07949	RET	Y185	P184L	184	Missense	proximal	-1	no	57.788	57.800	PhosphoSitePlus	TCGA;ICGC;COSMIC	28.094	Up-regulation
TK_Ret_RET_Y	P45983	MAPK8	P07949	RET	Y185	R189C	189	Missense	distal	4	no	57.788	55.628	PhosphoSitePlus	TCGA;ICGC;COSMIC	28.094	Down-regulation
TK_Ret_RET_Y	P45983	MAPK8	P07949	RET	Y185	R189L	189	Missense	distal	4	no	57.788	56.292	PhosphoSitePlus	TCGA;ICGC;COSMIC	28.094	Down-regulation
TK_Ret_RET_Y	P45983	MAPK8	P07949	RET	Y185	R189H	189	Missense	distal	4	no	57.788	55.597	PhosphoSitePlus	TCGA;ICGC;COSMIC	28.094	Down-regulation
TK_Ret_RET_Y	P27361	MAPK3	P07949	RET	Y204	R211W	211	Missense	distal	7	no	57.849	52.133	PhosphoSitePlus	TCGA	28.094	Down-regulation
TK_Ret_RET_Y	P27361	MAPK3	P07949	RET	Y222	D227N	227	Missense	distal	5	no	34.972	35.024	EPSD	TCGA;ICGC	28.094	Up-regulation
TK_Ret_RET_Y	Q16539	MAPK14	P07949	RET	Y182	R186K	186	Missense	distal	4	no	61.617	61.707	PhosphoSitePlus	TCGA;ICGC;COSMIC	28.094	Up-regulation
AGC_Akt_AKT1_ST	P19634	SLC9A1	P31749	AKT1	S648	T653M	653	Missense	distal	5	no	15.140	15.083	PhosphoSitePlus;EPSD	TCGA;ICGC;COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	P19634	SLC9A1	P31749	AKT1	S703	R698P	698	Missense	distal	-5	no	15.032	11.021	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	P19634	SLC9A1	P31749	AKT1	S703	S703L	703	Missense	central	0	yes	15.032	0.000	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	7.780	Loss
AGC_Akt_AKT1_ST	P19634	SLC9A1	P31749	AKT1	S770	S770L	770	Missense	central	0	yes	12.104	0.000	EPSD	TCGA;COSMIC	7.780	Loss
AGC_Akt_AKT1_ST	P19634	SLC9A1	P31749	AKT1	S770	R765W	765	Missense	distal	-5	no	12.104	6.584	EPSD	TCGA;ICGC;COSMIC;GDSC	7.780	Loss
AGC_Akt_AKT1_ST	P19634	SLC9A1	P31749	AKT1	S787	A781V	781	Missense	distal	-6	no	8.218	8.198	EPSD	TCGA;COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	P19634	SLC9A1	P31749	AKT1	S787	A781T	781	Missense	distal	-6	no	8.218	8.304	EPSD	TCGA;COSMIC	7.780	Up-regulation
AGC_Akt_AKT1_ST	P19634	SLC9A1	P31749	AKT1	S787	S787I	787	Missense	central	0	yes	8.218	0.000	EPSD	TCGA;COSMIC	7.780	Loss
AGC_Akt_AKT1_ST	Q06187	BTK	P31749	AKT1	S21	S14Y	14	Missense	distal	-7	no	8.937	8.731	EPSD	TCGA;ICGC;COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	Q06187	BTK	P31749	AKT1	S21	P22L	22	Missense	proximal	1	no	8.937	9.191	EPSD	TCGA;ICGC	7.780	Up-regulation
AGC_Akt_AKT1_ST	Q06187	BTK	P31749	AKT1	S21	S14T	14	Missense	distal	-7	no	8.937	8.987	EPSD	TCGA;ICGC;COSMIC	7.780	Up-regulation
AGC_Akt_AKT1_ST	Q06187	BTK	P31749	AKT1	S21	R28C	28	Missense	distal	7	no	8.937	8.807	EPSD	TCGA;ICGC;COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	Q06187	BTK	P31749	AKT1	S21	K26N	26	Missense	distal	5	no	8.937	8.901	EPSD	TCGA;ICGC;COSMIC;GDSC;CCLE	7.780	Down-regulation
AGC_Akt_AKT1_ST	Q06187	BTK	P31749	AKT1	S21	F25L	25	Missense	distal	4	no	8.937	8.929	EPSD	TCGA;ICGC;COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	Q06187	BTK	P31749	AKT1	S51	S51N	51	Missense	central	0	yes	15.721	0.000	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	7.780	Loss
AGC_Akt_AKT1_ST	Q06187	BTK	P31749	AKT1	S51	I56V	56	Missense	distal	5	no	15.721	15.758	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	7.780	Up-regulation
AGC_Akt_AKT1_ST	Q06187	BTK	P31749	AKT1	S51	K53T	53	Missense	proximal	2	no	15.721	15.630	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	Q06187	BTK	P31749	AKT1	S86	E88D	88	Missense	proximal	2	no	10.175	9.765	EPSD	TCGA;ICGC;COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	Q06187	BTK	P31749	AKT1	S86	Q91K	91	Missense	distal	5	no	10.175	10.220	EPSD	TCGA;ICGC;COSMIC	7.780	Up-regulation
AGC_Akt_AKT1_ST	Q06187	BTK	P31749	AKT1	S86	R81K	81	Missense	distal	-5	no	10.175	7.778	EPSD	TCGA;ICGC;COSMIC	7.780	Loss
AGC_Akt_AKT1_ST	Q06187	BTK	P31749	AKT1	S86	E88K	88	Missense	proximal	2	no	10.175	10.380	EPSD	TCGA;ICGC;COSMIC	7.780	Up-regulation
AGC_Akt_AKT1_ST	Q06187	BTK	P31749	AKT1	S86	Q91H	91	Missense	distal	5	no	10.175	10.152	EPSD	TCGA;ICGC;COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	Q06187	BTK	P31749	AKT1	S87	E88D	88	Missense	proximal	1	no	8.724	8.606	EPSD	TCGA;ICGC;COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	Q06187	BTK	P31749	AKT1	S87	Q91K	91	Missense	distal	4	no	8.724	8.567	EPSD	TCGA;ICGC;COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	Q06187	BTK	P31749	AKT1	S87	R81K	81	Missense	distal	-6	no	8.724	8.709	EPSD	TCGA;ICGC;COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	Q06187	BTK	P31749	AKT1	S87	E88K	88	Missense	proximal	1	no	8.724	8.887	EPSD	TCGA;ICGC;COSMIC	7.780	Up-regulation
AGC_Akt_AKT1_ST	Q06187	BTK	P31749	AKT1	S87	Q91H	91	Missense	distal	4	no	8.724	8.785	EPSD	TCGA;ICGC;COSMIC	7.780	Up-regulation
AGC_Akt_AKT1_ST	Q06187	BTK	P31749	AKT1	S174	S180F	180	Missense	distal	6	no	13.063	12.944	EPSD	TCGA;ICGC;COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	Q06187	BTK	P31749	AKT1	S174	L168V	168	Missense	distal	-6	no	13.063	13.039	EPSD	TCGA;ICGC	7.780	Down-regulation
AGC_Akt_AKT1_ST	Q06187	BTK	P31749	AKT1	S174	I167V	167	Missense	distal	-7	no	13.063	13.158	EPSD	TCGA;ICGC;COSMIC	7.780	Up-regulation
AGC_Akt_AKT1_ST	Q06187	BTK	P31749	AKT1	S174	R171S	171	Missense	distal	-3	no	13.063	5.287	EPSD	TCGA;ICGC;COSMIC	7.780	Loss
AGC_Akt_AKT1_ST	Q06187	BTK	P31749	AKT1	S174	I167M	167	Missense	distal	-7	no	13.063	13.220	EPSD	TCGA;ICGC;COSMIC	7.780	Up-regulation
AGC_Akt_AKT1_ST	Q06187	BTK	P31749	AKT1	S310	A312S	312	Missense	proximal	2	no	9.280	9.655	EPSD	TCGA;ICGC;COSMIC	7.780	Up-regulation
AGC_Akt_AKT1_ST	Q06187	BTK	P31749	AKT1	T495	R490C	490	Missense	distal	-5	no	14.279	10.203	PhosphoSitePlus;EPSD	TCGA;ICGC;COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	Q06187	BTK	P31749	AKT1	T495	F493L	493	Missense	proximal	-2	no	14.279	14.289	PhosphoSitePlus;EPSD	TCGA;ICGC;COSMIC	7.780	Up-regulation
AGC_Akt_AKT1_ST	Q06187	BTK	P31749	AKT1	T495	Q496H	496	Missense	proximal	1	no	14.279	14.252	PhosphoSitePlus;EPSD	TCGA;ICGC;COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	Q06187	BTK	P31749	AKT1	T495	H491D	491	Missense	distal	-4	no	14.279	13.965	PhosphoSitePlus;EPSD	TCGA;ICGC;COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	Q06187	BTK	P31749	AKT1	T495	M501V	501	Missense	distal	6	no	14.279	14.265	PhosphoSitePlus;EPSD	TCGA;ICGC;COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	Q06187	BTK	P31749	AKT1	T495	R490H	490	Missense	distal	-5	no	14.279	11.185	PhosphoSitePlus;EPSD	TCGA;ICGC;COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	Q06187	BTK	P31749	AKT1	S623	A622G	622	Missense	proximal	-1	no	10.647	10.638	EPSD	TCGA;ICGC;COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	Q06187	BTK	P31749	AKT1	S623	L621M	621	Missense	proximal	-2	no	10.647	10.664	EPSD	TCGA;ICGC;COSMIC	7.780	Up-regulation
AGC_Akt_AKT1_ST	Q06187	BTK	P31749	AKT1	S623	E624K	624	Missense	proximal	1	no	10.647	10.811	EPSD	TCGA;ICGC;COSMIC	7.780	Up-regulation
AGC_Akt_AKT1_ST	Q06187	BTK	P31749	AKT1	S623	Y627C	627	Missense	distal	4	no	10.647	10.856	EPSD	TCGA;ICGC;COSMIC	7.780	Up-regulation
AGC_Akt_AKT1_ST	Q06187	BTK	P31749	AKT1	S623	Y617C	617	Missense	distal	-6	no	10.647	10.560	EPSD	TCGA;ICGC	7.780	Down-regulation
AGC_Akt_AKT1_ST	Q9NR28	DIABLO	P31749	AKT1	T13	R10H	10	Missense	distal	-3	no	12.671	7.972	EPSD	TCGA;ICGC;COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	Q9NR28	DIABLO	P31749	AKT1	T220	E215K	215	Missense	distal	-5	no	10.595	12.293	EPSD	TCGA;COSMIC	7.780	Up-regulation
AGC_Akt_AKT1_ST	Q9NR28	DIABLO	P31749	AKT1	T220	R227W	227	Missense	distal	7	no	10.595	10.497	EPSD	TCGA;COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	Q9NR28	DIABLO	P31749	AKT1	S230	E231Q	231	Missense	proximal	1	no	13.712	13.658	EPSD	TCGA;COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	Q9NR28	DIABLO	P31749	AKT1	S230	R227W	227	Missense	distal	-3	no	13.712	4.772	EPSD	TCGA;COSMIC	7.780	Loss
AGC_Akt_AKT1_ST	Q9NR28	DIABLO	P31749	AKT1	S230	S230P	230	Missense	central	0	yes	13.712	0.000	EPSD	TCGA;COSMIC	7.780	Loss
AGC_Akt_AKT1_ST	O43521	BCL2L11	P31749	AKT1	T34	G31R	31	Missense	distal	-3	no	8.560	15.316	EPSD	TCGA;ICGC;COSMIC	7.780	Up-regulation
AGC_Akt_AKT1_ST	O43521	BCL2L11	P31749	AKT1	T34	G31E	31	Missense	distal	-3	no	8.560	8.745	EPSD	TCGA;ICGC;COSMIC	7.780	Up-regulation
AGC_Akt_AKT1_ST	O43521	BCL2L11	P31749	AKT1	S87	R91Q	91	Missense	distal	4	no	10.333	10.456	PhosphoSitePlus	TCGA;ICGC;COSMIC	7.780	Up-regulation
AGC_Akt_AKT1_ST	O43521	BCL2L11	P31749	AKT1	S87	R85I	85	Missense	proximal	-2	no	10.333	9.280	PhosphoSitePlus	TCGA;ICGC;COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	O43521	BCL2L11	P31749	AKT1	S87	L88M	88	Missense	proximal	1	no	10.333	10.171	PhosphoSitePlus	TCGA;ICGC;COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	O43521	BCL2L11	P31749	AKT1	S87	R84T	84	Missense	distal	-3	no	10.333	3.311	PhosphoSitePlus	TCGA;ICGC;COSMIC	7.780	Loss
AGC_Akt_AKT1_ST	O43521	BCL2L11	P31749	AKT1	S90	R91Q	91	Missense	proximal	1	no	8.219	7.924	EPSD	TCGA;ICGC;COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	O43521	BCL2L11	P31749	AKT1	S90	R85I	85	Missense	distal	-5	no	8.219	3.651	EPSD	TCGA;ICGC;COSMIC	7.780	Loss
AGC_Akt_AKT1_ST	O43521	BCL2L11	P31749	AKT1	S90	L88M	88	Missense	proximal	-2	no	8.219	8.235	EPSD	TCGA;ICGC;COSMIC	7.780	Up-regulation
AGC_Akt_AKT1_ST	O43521	BCL2L11	P31749	AKT1	S90	R84T	84	Missense	distal	-6	no	8.219	8.215	EPSD	TCGA;ICGC;COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	O43521	BCL2L11	P31749	AKT1	S90	Y96C	96	Missense	distal	6	no	8.219	8.104	EPSD	TCGA;ICGC;COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	O43521	BCL2L11	P31749	AKT1	S94	R91Q	91	Missense	distal	-3	no	13.394	6.182	EPSD	TCGA;ICGC;COSMIC	7.780	Loss
AGC_Akt_AKT1_ST	O43521	BCL2L11	P31749	AKT1	S94	L88M	88	Missense	distal	-6	no	13.394	13.382	EPSD	TCGA;ICGC;COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	O43521	BCL2L11	P31749	AKT1	S94	Y96C	96	Missense	proximal	2	no	13.394	12.941	EPSD	TCGA;ICGC;COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	P29474	NOS3	P31749	AKT1	S102	R97K	97	Missense	distal	-5	no	10.188	7.791	EPSD	TCGA;ICGC;COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	P29474	NOS3	P31749	AKT1	S260	R262Q	262	Missense	proximal	2	no	7.871	7.753	EPSD	TCGA;ICGC;COSMIC	7.780	Loss
AGC_Akt_AKT1_ST	P29474	NOS3	P31749	AKT1	T495	T488A	488	Missense	distal	-7	no	11.190	10.990	EPSD	TCGA;ICGC;COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	P29474	NOS3	P31749	AKT1	S615	R612C	612	Missense	distal	-3	no	11.942	5.768	PhosphoSitePlus;EPSD	TCGA;ICGC;COSMIC	7.780	Loss
AGC_Akt_AKT1_ST	P29474	NOS3	P31749	AKT1	S615	S617F	617	Missense	proximal	2	no	11.942	11.364	PhosphoSitePlus;EPSD	TCGA;ICGC;COSMIC;GDSC	7.780	Down-regulation
AGC_Akt_AKT1_ST	P29474	NOS3	P31749	AKT1	S615	R612H	612	Missense	distal	-3	no	11.942	7.243	PhosphoSitePlus;EPSD	TCGA;ICGC;COSMIC	7.780	Loss
AGC_Akt_AKT1_ST	P29474	NOS3	P31749	AKT1	S633	G640V	640	Missense	distal	7	no	17.774	17.793	EPSD	TCGA;ICGC;COSMIC	7.780	Up-regulation
AGC_Akt_AKT1_ST	P29474	NOS3	P31749	AKT1	S634	G640V	640	Missense	distal	6	no	10.558	10.550	EPSD	TCGA;ICGC;COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	P29474	NOS3	P31749	AKT1	T785	L783M	783	Missense	proximal	-2	no	9.168	9.185	EPSD	TCGA;ICGC;COSMIC	7.780	Up-regulation
AGC_Akt_AKT1_ST	P29474	NOS3	P31749	AKT1	T1175	R1172H	1172	Missense	distal	-3	no	11.266	6.568	EPSD	TCGA;ICGC;COSMIC;GDSC;CCLE	7.780	Loss
AGC_Akt_AKT1_ST	P29474	NOS3	P31749	AKT1	T1175	E1182A	1182	Missense	distal	7	no	11.266	11.250	EPSD	TCGA;ICGC;COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	P29474	NOS3	P31749	AKT1	T1175	R1174H	1174	Missense	proximal	-1	no	11.266	11.222	EPSD	TCGA;ICGC	7.780	Down-regulation
AGC_Akt_AKT1_ST	P29474	NOS3	P31749	AKT1	S1177	R1172H	1172	Missense	distal	-5	no	17.081	13.986	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC;GDSC;CCLE	7.780	Down-regulation
AGC_Akt_AKT1_ST	P29474	NOS3	P31749	AKT1	S1177	E1182A	1182	Missense	distal	5	no	17.081	17.063	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	P29474	NOS3	P31749	AKT1	S1177	R1183C	1183	Missense	distal	6	no	17.081	16.880	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	P29474	NOS3	P31749	AKT1	S1177	R1174H	1174	Missense	distal	-3	no	17.081	12.382	EPSD;PhosphoSitePlus	TCGA;ICGC	7.780	Down-regulation
AGC_Akt_AKT1_ST	P29474	NOS3	P31749	AKT1	S1179	R1172H	1172	Missense	distal	-7	no	11.305	11.004	EPSD	TCGA;ICGC;COSMIC;GDSC;CCLE	7.780	Down-regulation
AGC_Akt_AKT1_ST	P29474	NOS3	P31749	AKT1	S1179	E1182A	1182	Missense	distal	3	no	11.305	11.288	EPSD	TCGA;ICGC;COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	P29474	NOS3	P31749	AKT1	S1179	R1183C	1183	Missense	distal	4	no	11.305	11.639	EPSD	TCGA;ICGC;COSMIC	7.780	Up-regulation
AGC_Akt_AKT1_ST	P29474	NOS3	P31749	AKT1	S1179	R1174H	1174	Missense	distal	-5	no	11.305	8.210	EPSD	TCGA;ICGC	7.780	Down-regulation
AGC_Akt_AKT1_ST	Q86V81	ALYREF	P31749	AKT1	S194	R197S	197	Missense	distal	3	no	10.907	10.924	EPSD	TCGA;COSMIC	7.780	Up-regulation
AGC_Akt_AKT1_ST	Q86V81	ALYREF	P31749	AKT1	T219	G214A	214	Missense	distal	-5	no	11.247	11.457	EPSD;PhosphoSitePlus	TCGA;COSMIC	7.780	Up-regulation
AGC_Akt_AKT1_ST	P19484	TFEB	P31749	AKT1	S132	A135T	135	Missense	distal	3	no	7.737	7.794	EPSD	TCGA;ICGC;COSMIC;GDSC;CCLE	7.780	Gain
AGC_Akt_AKT1_ST	P19484	TFEB	P31749	AKT1	S227	R220Q	220	Missense	distal	-7	no	7.870	7.675	EPSD	TCGA;ICGC;COSMIC	7.780	Loss
AGC_Akt_AKT1_ST	P19484	TFEB	P31749	AKT1	S227	E233D	233	Missense	distal	6	no	7.870	7.779	EPSD	TCGA;ICGC;COSMIC	7.780	Loss
AGC_Akt_AKT1_ST	P19484	TFEB	P31749	AKT1	S227	E233K	233	Missense	distal	6	no	7.870	7.939	EPSD	TCGA;ICGC;COSMIC	7.780	Up-regulation
AGC_Akt_AKT1_ST	P19484	TFEB	P31749	AKT1	S463	S467I	467	Missense	distal	4	no	11.685	11.946	EPSD	TCGA;COSMIC	7.780	Up-regulation
AGC_Akt_AKT1_ST	P19484	TFEB	P31749	AKT1	S467	S467I	467	Missense	central	0	yes	15.178	0.000	PhosphoSitePlus	TCGA;COSMIC	7.780	Loss
AGC_Akt_AKT1_ST	P19484	TFEB	P31749	AKT1	S469	S467I	467	Missense	proximal	-2	no	11.305	10.064	EPSD	TCGA;COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	P31749	AKT1	P31749	AKT1	T72	T65M	65	Missense	distal	-7	no	15.377	15.111	PhosphoSitePlus;EPSD	TCGA;ICGC;COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	P31749	AKT1	P31749	AKT1	T72	R69W	69	Missense	distal	-3	no	15.377	6.437	PhosphoSitePlus;EPSD	TCGA;ICGC;COSMIC	7.780	Loss
AGC_Akt_AKT1_ST	P31749	AKT1	P31749	AKT1	T72	Q79K	79	Missense	distal	7	no	15.377	15.426	PhosphoSitePlus;EPSD	TCGA;ICGC;COSMIC	7.780	Up-regulation
AGC_Akt_AKT1_ST	P31749	AKT1	P31749	AKT1	S124	R121W	121	Missense	distal	-3	no	10.847	1.906	EPSD	TCGA;ICGC;COSMIC	7.780	Loss
AGC_Akt_AKT1_ST	P31749	AKT1	P31749	AKT1	S124	A131T	131	Missense	distal	7	no	10.847	10.908	EPSD	TCGA;ICGC;COSMIC	7.780	Up-regulation
AGC_Akt_AKT1_ST	P31749	AKT1	P31749	AKT1	S126	E132K	132	Missense	distal	6	no	8.454	8.523	EPSD	TCGA;COSMIC	7.780	Up-regulation
AGC_Akt_AKT1_ST	P31749	AKT1	P31749	AKT1	S126	R121W	121	Missense	distal	-5	no	8.454	2.934	EPSD	TCGA;ICGC;COSMIC	7.780	Loss
AGC_Akt_AKT1_ST	P31749	AKT1	P31749	AKT1	S126	E133D	133	Missense	distal	7	no	8.454	8.411	EPSD	TCGA;ICGC;COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	P31749	AKT1	P31749	AKT1	S126	A131T	131	Missense	distal	5	no	8.454	8.505	EPSD	TCGA;ICGC;COSMIC	7.780	Up-regulation
AGC_Akt_AKT1_ST	P31749	AKT1	P31749	AKT1	S422	Y417C	417	Missense	distal	-5	no	8.142	8.673	EPSD	TCGA;ICGC;COSMIC	7.780	Up-regulation
AGC_Akt_AKT1_ST	P31749	AKT1	P31749	AKT1	S422	P423T	423	Missense	proximal	1	no	8.142	8.490	EPSD	TCGA;ICGC	7.780	Up-regulation
AGC_Akt_AKT1_ST	P31749	AKT1	P31749	AKT1	S422	E418K	418	Missense	distal	-4	no	8.142	8.726	EPSD	TCGA;ICGC	7.780	Up-regulation
AGC_Akt_AKT1_ST	P31749	AKT1	P31749	AKT1	S473	S475L	475	Missense	proximal	2	no	7.952	7.406	EPSD	TCGA;ICGC;COSMIC	7.780	Loss
AGC_Akt_AKT1_ST	P31749	AKT1	P31749	AKT1	S475	S475L	475	Missense	central	0	yes	7.786	0.000	EPSD	TCGA;ICGC;COSMIC	7.780	Loss
AGC_Akt_AKT1_ST	P19174	PLCG1	P31749	AKT1	S451	G448R	448	Missense	distal	-3	no	2.997	9.753	EPSD	TCGA;ICGC;COSMIC	7.780	Gain
AGC_Akt_AKT1_ST	P19174	PLCG1	P31749	AKT1	S539	E537K	537	Missense	proximal	-2	no	7.472	8.131	EPSD	TCGA;ICGC;COSMIC	7.780	Gain
AGC_Akt_AKT1_ST	P19174	PLCG1	P31749	AKT1	S540	E537K	537	Missense	distal	-3	no	6.125	8.176	EPSD	TCGA;ICGC;COSMIC	7.780	Gain
AGC_Akt_AKT1_ST	P19174	PLCG1	P31749	AKT1	S541	E537K	537	Missense	distal	-4	no	7.354	7.938	EPSD	TCGA;ICGC;COSMIC	7.780	Gain
AGC_Akt_AKT1_ST	P19174	PLCG1	P31749	AKT1	S701	R694Q	694	Missense	distal	-7	no	8.721	8.527	EPSD	TCGA;ICGC;COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	P19174	PLCG1	P31749	AKT1	S701	R696W	696	Missense	distal	-5	no	8.721	3.201	EPSD	TCGA;ICGC;COSMIC	7.780	Loss
AGC_Akt_AKT1_ST	P19174	PLCG1	P31749	AKT1	S981	Y977C	977	Missense	distal	-4	no	10.532	9.798	EPSD	TCGA;ICGC;COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	P19174	PLCG1	P31749	AKT1	S981	R978W	978	Missense	distal	-3	no	10.532	1.591	EPSD	TCGA;ICGC;COSMIC	7.780	Loss
AGC_Akt_AKT1_ST	P19174	PLCG1	P31749	AKT1	S981	S982F	982	Missense	proximal	1	no	10.532	10.549	EPSD	TCGA;ICGC;COSMIC	7.780	Up-regulation
AGC_Akt_AKT1_ST	P29375	KDM5A	P31749	AKT1	T223	V230L	230	Missense	distal	7	no	12.552	12.540	EPSD	TCGA;ICGC;COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	P29375	KDM5A	P31749	AKT1	S225	S231N	231	Missense	distal	6	no	13.181	13.114	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	P29375	KDM5A	P31749	AKT1	S225	V230L	230	Missense	distal	5	no	13.181	13.175	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	P29375	KDM5A	P31749	AKT1	T285	G284D	284	Missense	proximal	-1	no	16.140	16.121	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	P29375	KDM5A	P31749	AKT1	S287	G284D	284	Missense	distal	-3	no	10.380	11.185	PhosphoSitePlus;EPSD	TCGA;ICGC;COSMIC	7.780	Up-regulation
AGC_Akt_AKT1_ST	P29375	KDM5A	P31749	AKT1	T362	R359L	359	Missense	distal	-3	no	10.750	3.756	EPSD	TCGA;ICGC;COSMIC	7.780	Loss
AGC_Akt_AKT1_ST	P29375	KDM5A	P31749	AKT1	T362	G367E	367	Missense	distal	5	no	10.750	10.781	EPSD	TCGA;ICGC;COSMIC	7.780	Up-regulation
AGC_Akt_AKT1_ST	P29375	KDM5A	P31749	AKT1	S973	S970I	970	Missense	distal	-3	no	7.514	8.209	EPSD	TCGA;ICGC;COSMIC	7.780	Gain
AGC_Akt_AKT1_ST	P29375	KDM5A	P31749	AKT1	S1067	T1060M	1060	Missense	distal	-7	no	8.000	7.733	EPSD	TCGA;ICGC;COSMIC	7.780	Loss
AGC_Akt_AKT1_ST	P29375	KDM5A	P31749	AKT1	T1225	T1225I	1225	Missense	central	0	yes	15.216	0.000	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	7.780	Loss
AGC_Akt_AKT1_ST	P29375	KDM5A	P31749	AKT1	T1225	R1219Q	1219	Missense	distal	-6	no	15.216	15.131	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	P29375	KDM5A	P31749	AKT1	S1255	R1259T	1259	Missense	distal	4	no	12.019	12.003	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	P29375	KDM5A	P31749	AKT1	S1255	A1253V	1253	Missense	proximal	-2	no	12.019	11.280	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	P29375	KDM5A	P31749	AKT1	S1255	R1261W	1261	Missense	distal	6	no	12.019	11.860	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	P29375	KDM5A	P31749	AKT1	S1255	R1259I	1259	Missense	distal	4	no	12.019	12.269	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	7.780	Up-regulation
AGC_Akt_AKT1_ST	P29375	KDM5A	P31749	AKT1	S1255	A1260V	1260	Missense	distal	5	no	12.019	12.010	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	P29375	KDM5A	P31749	AKT1	T1292	E1285G	1285	Missense	distal	-7	no	11.073	11.037	EPSD	TCGA;ICGC;COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	P29375	KDM5A	P31749	AKT1	T1292	I1296M	1296	Missense	distal	4	no	11.073	10.975	EPSD	TCGA;ICGC;COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	P29375	KDM5A	P31749	AKT1	S1326	S1319F	1319	Missense	distal	-7	no	11.803	11.525	EPSD	TCGA;ICGC;COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	P29375	KDM5A	P31749	AKT1	S1326	V1328M	1328	Missense	proximal	2	no	11.803	11.924	EPSD	TCGA;ICGC;COSMIC	7.780	Up-regulation
AGC_Akt_AKT1_ST	P29375	KDM5A	P31749	AKT1	S1326	S1327N	1327	Missense	proximal	1	no	11.803	11.714	EPSD	TCGA;ICGC	7.780	Down-regulation
AGC_Akt_AKT1_ST	P29375	KDM5A	P31749	AKT1	S1408	S1403F	1403	Missense	distal	-5	no	7.540	8.489	EPSD	TCGA;ICGC;COSMIC	7.780	Gain
AGC_Akt_AKT1_ST	P29375	KDM5A	P31749	AKT1	S1410	S1403F	1403	Missense	distal	-7	no	8.778	8.501	EPSD	TCGA;ICGC;COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	P29375	KDM5A	P31749	AKT1	S1410	S1404Y	1404	Missense	distal	-6	no	8.778	8.719	EPSD	TCGA;ICGC;COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	P29375	KDM5A	P31749	AKT1	S1410	S1410F	1410	Missense	central	0	yes	8.778	0.000	EPSD	TCGA;ICGC;COSMIC	7.780	Loss
AGC_Akt_AKT1_ST	P29375	KDM5A	P31749	AKT1	S1423	P1420R	1420	Missense	distal	-3	no	7.576	14.215	EPSD	TCGA;ICGC;COSMIC	7.780	Gain
AGC_Akt_AKT1_ST	P29375	KDM5A	P31749	AKT1	S1678	P1671T	1671	Missense	distal	-7	no	7.681	7.925	EPSD	TCGA;ICGC;COSMIC	7.780	Gain
AGC_Akt_AKT1_ST	P49815	TSC2	P31749	AKT1	S188	K185R	185	Missense	distal	-3	no	6.683	11.204	EPSD	TCGA;ICGC	7.780	Gain
AGC_Akt_AKT1_ST	P49815	TSC2	P31749	AKT1	S311	S311F	311	Missense	central	0	yes	11.618	0.000	EPSD	TCGA;ICGC;COSMIC	7.780	Loss
AGC_Akt_AKT1_ST	P49815	TSC2	P31749	AKT1	S540	R537H	537	Missense	distal	-3	no	11.290	6.591	EPSD	TCGA;ICGC;COSMIC	7.780	Loss
AGC_Akt_AKT1_ST	P49815	TSC2	P31749	AKT1	S660	K657R	657	Missense	distal	-3	no	7.134	11.655	EPSD	TCGA;ICGC;COSMIC	7.780	Gain
AGC_Akt_AKT1_ST	P49815	TSC2	P31749	AKT1	S937	R943K	943	Missense	distal	6	no	11.585	11.597	EPSD	TCGA;ICGC;COSMIC	7.780	Up-regulation
AGC_Akt_AKT1_ST	P49815	TSC2	P31749	AKT1	S937	R934S	934	Missense	distal	-3	no	11.585	3.809	EPSD	TCGA;ICGC;COSMIC	7.780	Loss
AGC_Akt_AKT1_ST	P49815	TSC2	P31749	AKT1	S939	R943K	943	Missense	distal	4	no	15.360	15.327	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	P49815	TSC2	P31749	AKT1	S939	R934S	934	Missense	distal	-5	no	15.360	10.890	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	P49815	TSC2	P31749	AKT1	S946	R943K	943	Missense	distal	-3	no	10.866	6.346	EPSD	TCGA;ICGC;COSMIC	7.780	Loss
AGC_Akt_AKT1_ST	P49815	TSC2	P31749	AKT1	S979	R978H	978	Missense	proximal	-1	no	9.108	9.063	EPSD	TCGA;ICGC;COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	P49815	TSC2	P31749	AKT1	S981	R978H	978	Missense	distal	-3	no	14.283	9.584	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	P49815	TSC2	P31749	AKT1	S983	R978H	978	Missense	distal	-5	no	9.011	5.916	EPSD	TCGA;ICGC;COSMIC	7.780	Loss
AGC_Akt_AKT1_ST	P49815	TSC2	P31749	AKT1	S1130	L1137F	1137	Missense	distal	7	no	15.071	15.064	EPSD	TCGA;COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	P49815	TSC2	P31749	AKT1	S1130	R1127Q	1127	Missense	distal	-3	no	15.071	7.860	EPSD	TCGA	7.780	Down-regulation
AGC_Akt_AKT1_ST	P49815	TSC2	P31749	AKT1	S1132	L1137F	1137	Missense	distal	5	no	14.362	14.356	EPSD	TCGA;COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	P49815	TSC2	P31749	AKT1	S1132	R1127Q	1127	Missense	distal	-5	no	14.362	10.135	EPSD	TCGA	7.780	Down-regulation
AGC_Akt_AKT1_ST	P49815	TSC2	P31749	AKT1	T1271	R1268C	1268	Missense	distal	-3	no	11.438	5.265	EPSD	TCGA;COSMIC;CCLE	7.780	Loss
AGC_Akt_AKT1_ST	P49815	TSC2	P31749	AKT1	T1271	P1264L	1264	Missense	distal	-7	no	11.438	11.399	EPSD	TCGA;COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	P49815	TSC2	P31749	AKT1	T1271	P1265H	1265	Missense	distal	-6	no	11.438	11.418	EPSD	TCGA	7.780	Down-regulation
AGC_Akt_AKT1_ST	P49815	TSC2	P31749	AKT1	S1334	S1341N	1341	Missense	distal	7	no	11.126	11.091	EPSD	TCGA;COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	P49815	TSC2	P31749	AKT1	S1338	E1343D	1343	Missense	distal	5	no	13.473	13.431	EPSD	TCGA	7.780	Down-regulation
AGC_Akt_AKT1_ST	P49815	TSC2	P31749	AKT1	S1338	S1341N	1341	Missense	distal	3	no	13.473	13.417	EPSD	TCGA;COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	P49815	TSC2	P31749	AKT1	S1340	E1343D	1343	Missense	distal	3	no	9.262	9.192	EPSD	TCGA	7.780	Down-regulation
AGC_Akt_AKT1_ST	P49815	TSC2	P31749	AKT1	S1340	S1341N	1341	Missense	proximal	1	no	9.262	9.174	EPSD	TCGA;COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	P49815	TSC2	P31749	AKT1	S1364	E1360K	1360	Missense	distal	-4	no	9.317	9.901	EPSD	TCGA	7.780	Up-regulation
AGC_Akt_AKT1_ST	P49815	TSC2	P31749	AKT1	S1387	S1386I	1386	Missense	proximal	-1	no	8.028	7.979	EPSD	TCGA;COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	P49815	TSC2	P31749	AKT1	S1454	S1449C	1449	Missense	distal	-5	no	10.888	11.282	EPSD	TCGA;COSMIC	7.780	Up-regulation
AGC_Akt_AKT1_ST	P49815	TSC2	P31749	AKT1	S1454	R1457Q	1457	Missense	distal	3	no	10.888	10.832	EPSD	TCGA;COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	P49815	TSC2	P31749	AKT1	S1454	R1451C	1451	Missense	distal	-3	no	10.888	4.715	EPSD	TCGA;COSMIC	7.780	Loss
AGC_Akt_AKT1_ST	P49815	TSC2	P31749	AKT1	T1462	S1466L	1466	Missense	distal	4	no	14.274	14.463	PhosphoSitePlus;EPSD	TCGA	7.780	Up-regulation
AGC_Akt_AKT1_ST	P49815	TSC2	P31749	AKT1	T1462	R1457Q	1457	Missense	distal	-5	no	14.274	10.047	PhosphoSitePlus;EPSD	TCGA;COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	P49815	TSC2	P31749	AKT1	S1464	S1466L	1466	Missense	proximal	2	no	8.023	7.478	EPSD	TCGA	7.780	Loss
AGC_Akt_AKT1_ST	P49815	TSC2	P31749	AKT1	S1464	R1457Q	1457	Missense	distal	-7	no	8.023	7.829	EPSD	TCGA;COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	P49815	TSC2	P31749	AKT1	S1798	E1805K	1805	Missense	distal	7	no	18.057	18.091	EPSD	TCGA;COSMIC	7.780	Up-regulation
AGC_Akt_AKT1_ST	P49815	TSC2	P31749	AKT1	S1798	S1798C	1798	Missense	central	0	yes	18.057	0.000	EPSD	TCGA;COSMIC	7.780	Loss
AGC_Akt_AKT1_ST	P49815	TSC2	P31749	AKT1	S1798	S1798F	1798	Missense	central	0	yes	18.057	0.000	EPSD	TCGA;COSMIC	7.780	Loss
AGC_Akt_AKT1_ST	P49815	TSC2	P31749	AKT1	S1799	E1805K	1805	Missense	distal	6	no	8.617	8.686	EPSD	TCGA;COSMIC	7.780	Up-regulation
AGC_Akt_AKT1_ST	P49815	TSC2	P31749	AKT1	S1799	S1798C	1798	Missense	proximal	-1	no	8.617	8.557	EPSD	TCGA;COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	P49815	TSC2	P31749	AKT1	S1799	S1798F	1798	Missense	proximal	-1	no	8.617	8.582	EPSD	TCGA;COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	Q15633	TARBP2	P31749	AKT1	T179	R174Q	174	Missense	distal	-5	no	8.679	4.452	EPSD	TCGA;COSMIC	7.780	Loss
AGC_Akt_AKT1_ST	Q15633	TARBP2	P31749	AKT1	T179	P186T	186	Missense	distal	7	no	8.679	8.748	EPSD	TCGA;COSMIC	7.780	Up-regulation
AGC_Akt_AKT1_ST	Q15633	TARBP2	P31749	AKT1	T179	P186S	186	Missense	distal	7	no	8.679	8.738	EPSD	TCGA;COSMIC	7.780	Up-regulation
AGC_Akt_AKT1_ST	Q15633	TARBP2	P31749	AKT1	S283	S286C	286	Missense	distal	3	no	10.998	10.821	PhosphoSitePlus	TCGA;COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	P14618	PKM	P31749	AKT1	S6	S2L	2	Missense	distal	-4	no	8.617	7.494	EPSD	TCGA;COSMIC	7.780	Loss
AGC_Akt_AKT1_ST	P14618	PKM	P31749	AKT1	S6	F12Y	12	Missense	distal	6	no	8.617	8.649	EPSD	TCGA;ICGC;COSMIC	7.780	Up-regulation
AGC_Akt_AKT1_ST	P14618	PKM	P31749	AKT1	T10	F12Y	12	Missense	proximal	2	no	8.264	8.469	EPSD	TCGA;ICGC;COSMIC	7.780	Up-regulation
AGC_Akt_AKT1_ST	P14618	PKM	P31749	AKT1	T10	S6T	6	Missense	distal	-4	no	8.264	8.320	EPSD	TCGA;ICGC;COSMIC	7.780	Up-regulation
AGC_Akt_AKT1_ST	P14618	PKM	P31749	AKT1	S37	R43P	43	Missense	distal	6	no	8.626	8.533	PhosphoSitePlus;EPSD	TCGA;ICGC;COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	P14618	PKM	P31749	AKT1	S37	R32C	32	Missense	distal	-5	no	8.626	4.549	PhosphoSitePlus;EPSD	TCGA;ICGC;COSMIC	7.780	Loss
AGC_Akt_AKT1_ST	P14618	PKM	P31749	AKT1	S37	R32H	32	Missense	distal	-5	no	8.626	5.531	PhosphoSitePlus;EPSD	TCGA;ICGC;COSMIC	7.780	Loss
AGC_Akt_AKT1_ST	P14618	PKM	P31749	AKT1	T95	D101N	101	Missense	distal	6	no	10.620	10.701	EPSD	TCGA;ICGC;COSMIC	7.780	Up-regulation
AGC_Akt_AKT1_ST	P14618	PKM	P31749	AKT1	T95	V91M	91	Missense	distal	-4	no	10.620	10.804	EPSD	TCGA;ICGC;COSMIC	7.780	Up-regulation
AGC_Akt_AKT1_ST	P14618	PKM	P31749	AKT1	T95	K89N	89	Missense	distal	-6	no	10.620	10.553	EPSD	TCGA;ICGC;COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	P14618	PKM	P31749	AKT1	T95	R92H	92	Missense	distal	-3	no	10.620	5.921	EPSD	TCGA;ICGC;COSMIC	7.780	Loss
AGC_Akt_AKT1_ST	P14618	PKM	P31749	AKT1	T95	R92C	92	Missense	distal	-3	no	10.620	4.446	EPSD	TCGA;ICGC;GDSC;CCLE	7.780	Loss
AGC_Akt_AKT1_ST	P14618	PKM	P31749	AKT1	S97	D101N	101	Missense	distal	4	no	11.366	11.251	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	P14618	PKM	P31749	AKT1	S97	V91M	91	Missense	distal	-6	no	11.366	11.380	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	7.780	Up-regulation
AGC_Akt_AKT1_ST	P14618	PKM	P31749	AKT1	S97	R92H	92	Missense	distal	-5	no	11.366	8.271	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	P14618	PKM	P31749	AKT1	S97	R92C	92	Missense	distal	-5	no	11.366	7.289	EPSD;PhosphoSitePlus	TCGA;ICGC;GDSC;CCLE	7.780	Loss
AGC_Akt_AKT1_ST	P14618	PKM	P31749	AKT1	S249	A242V	242	Missense	distal	-7	no	11.640	11.512	EPSD	TCGA;COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	P14618	PKM	P31749	AKT1	S519	T513I	513	Missense	distal	-6	no	12.016	11.865	EPSD	TCGA	7.780	Down-regulation
AGC_Akt_AKT1_ST	P14618	PKM	P31749	AKT1	S519	R516C	516	Missense	distal	-3	no	12.016	5.843	EPSD	TCGA;COSMIC	7.780	Loss
AGC_Akt_AKT1_ST	P02545	LMNA	P31749	AKT1	S51	G58R	58	Missense	distal	7	no	8.659	8.740	EPSD	TCGA;ICGC;COSMIC	7.780	Up-regulation
AGC_Akt_AKT1_ST	P02545	LMNA	P31749	AKT1	S51	L52V	52	Missense	proximal	1	no	8.659	8.559	EPSD	TCGA;ICGC;COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	P02545	LMNA	P31749	AKT1	S51	Y45C	45	Missense	distal	-6	no	8.659	8.572	EPSD	TCGA;ICGC;COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	P02545	LMNA	P31749	AKT1	S75	V69M	69	Missense	distal	-6	no	11.162	11.175	EPSD	TCGA;ICGC;COSMIC	7.780	Up-regulation
AGC_Akt_AKT1_ST	P02545	LMNA	P31749	AKT1	S75	K78N	78	Missense	distal	3	no	11.162	11.103	EPSD	TCGA;ICGC;COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	P02545	LMNA	P31749	AKT1	S149	R156C	156	Missense	distal	7	no	8.537	8.407	EPSD	TCGA	7.780	Down-regulation
AGC_Akt_AKT1_ST	P02545	LMNA	P31749	AKT1	S149	E154K	154	Missense	distal	5	no	8.537	8.571	EPSD	TCGA;ICGC;COSMIC	7.780	Up-regulation
AGC_Akt_AKT1_ST	P02545	LMNA	P31749	AKT1	S149	R156H	156	Missense	distal	7	no	8.537	8.466	EPSD	TCGA;COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	P02545	LMNA	P31749	AKT1	S149	A146V	146	Missense	distal	-3	no	8.537	7.975	EPSD	TCGA;COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	P02545	LMNA	P31749	AKT1	T157	E154K	154	Missense	distal	-3	no	6.248	8.299	EPSD	TCGA;ICGC;COSMIC	7.780	Gain
AGC_Akt_AKT1_ST	P02545	LMNA	P31749	AKT1	T224	N231S	231	Missense	distal	7	no	12.014	12.049	EPSD	TCGA;COSMIC	7.780	Up-regulation
AGC_Akt_AKT1_ST	P02545	LMNA	P31749	AKT1	T224	D230Y	230	Missense	distal	6	no	12.014	12.074	EPSD	TCGA;COSMIC	7.780	Up-regulation
AGC_Akt_AKT1_ST	P02545	LMNA	P31749	AKT1	T224	R220H	220	Missense	distal	-4	no	12.014	10.955	EPSD	TCGA	7.780	Down-regulation
AGC_Akt_AKT1_ST	P02545	LMNA	P31749	AKT1	T224	R221H	221	Missense	distal	-3	no	12.014	7.315	EPSD	TCGA;COSMIC	7.780	Loss
AGC_Akt_AKT1_ST	P02545	LMNA	P31749	AKT1	S268	A274T	274	Missense	distal	6	no	7.922	8.025	EPSD	TCGA	7.780	Up-regulation
AGC_Akt_AKT1_ST	P02545	LMNA	P31749	AKT1	S301	R296H	296	Missense	distal	-5	no	14.685	11.590	EPSD;PhosphoSitePlus	TCGA;COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	P02545	LMNA	P31749	AKT1	S301	A304T	304	Missense	distal	3	no	14.685	14.742	EPSD;PhosphoSitePlus	TCGA;COSMIC	7.780	Up-regulation
AGC_Akt_AKT1_ST	P02545	LMNA	P31749	AKT1	S303	R296H	296	Missense	distal	-7	no	9.098	8.797	EPSD	TCGA;COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	P02545	LMNA	P31749	AKT1	S303	A304T	304	Missense	proximal	1	no	9.098	9.365	EPSD	TCGA;COSMIC	7.780	Up-regulation
AGC_Akt_AKT1_ST	P02545	LMNA	P31749	AKT1	S326	R329H	329	Missense	distal	3	no	8.203	8.120	EPSD	TCGA;COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	P02545	LMNA	P31749	AKT1	S326	R329C	329	Missense	distal	3	no	8.203	8.043	EPSD	TCGA;COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	P02545	LMNA	P31749	AKT1	S326	R331W	331	Missense	distal	5	no	8.203	8.109	EPSD	TCGA;COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	P02545	LMNA	P31749	AKT1	S326	R321Q	321	Missense	distal	-5	no	8.203	3.976	EPSD	TCGA	7.780	Loss
AGC_Akt_AKT1_ST	P02545	LMNA	P31749	AKT1	S404	R399H	399	Missense	distal	-5	no	14.842	11.747	PhosphoSitePlus;EPSD	TCGA;COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	P02545	LMNA	P31749	AKT1	S404	R401C	401	Missense	distal	-3	no	14.842	8.669	PhosphoSitePlus;EPSD	TCGA;COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	P02545	LMNA	P31749	AKT1	S406	R399H	399	Missense	distal	-7	no	7.840	7.538	EPSD	TCGA;COSMIC	7.780	Loss
AGC_Akt_AKT1_ST	P02545	LMNA	P31749	AKT1	S406	R401C	401	Missense	distal	-5	no	7.840	3.763	EPSD	TCGA;COSMIC	7.780	Loss
AGC_Akt_AKT1_ST	P02545	LMNA	P31749	AKT1	S406	G413D	413	Missense	distal	7	no	7.840	7.836	EPSD	TCGA	7.780	Down-regulation
AGC_Akt_AKT1_ST	P02545	LMNA	P31749	AKT1	S458	R453Q	453	Missense	distal	-5	no	14.905	10.677	EPSD	TCGA	7.780	Down-regulation
AGC_Akt_AKT1_ST	P02545	LMNA	P31749	AKT1	S458	R453W	453	Missense	distal	-5	no	14.905	9.385	EPSD	TCGA	7.780	Down-regulation
AGC_Akt_AKT1_ST	P02545	LMNA	P31749	AKT1	S458	S463F	463	Missense	distal	5	no	14.905	14.832	EPSD	TCGA	7.780	Down-regulation
AGC_Akt_AKT1_ST	P02545	LMNA	P31749	AKT1	T585	R584H	584	Missense	proximal	-1	no	8.795	8.751	EPSD	TCGA	7.780	Down-regulation
AGC_Akt_AKT1_ST	P02545	LMNA	P31749	AKT1	T585	G589R	589	Missense	distal	4	no	8.795	8.633	EPSD	TCGA;COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	P02545	LMNA	P31749	AKT1	T585	S583L	583	Missense	proximal	-2	no	8.795	7.939	EPSD	TCGA;COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	P02545	LMNA	P31749	AKT1	S632	G631S	631	Missense	proximal	-1	no	9.330	9.359	EPSD	TCGA;COSMIC	7.780	Up-regulation
AGC_Akt_AKT1_ST	P02545	LMNA	P31749	AKT1	S657	N660S	660	Missense	distal	3	no	12.872	12.928	EPSD	TCGA;COSMIC	7.780	Up-regulation
AGC_Akt_AKT1_ST	P38398	BRCA1	P31749	AKT1	S335	L342M	342	Missense	distal	7	no	12.299	12.306	EPSD	TCGA	7.780	Up-regulation
AGC_Akt_AKT1_ST	P38398	BRCA1	P31749	AKT1	T336	L342M	342	Missense	distal	6	no	7.874	7.879	EPSD	TCGA	7.780	Up-regulation
AGC_Akt_AKT1_ST	P38398	BRCA1	P31749	AKT1	S449	R446T	446	Missense	distal	-3	no	10.000	2.978	EPSD	TCGA;COSMIC	7.780	Loss
AGC_Akt_AKT1_ST	P38398	BRCA1	P31749	AKT1	S451	R446T	446	Missense	distal	-5	no	10.512	6.783	EPSD	TCGA;COSMIC	7.780	Loss
AGC_Akt_AKT1_ST	P38398	BRCA1	P31749	AKT1	T509	E515Q	515	Missense	distal	6	no	15.352	15.338	PhosphoSitePlus;EPSD	TCGA;COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	P38398	BRCA1	P31749	AKT1	T509	E515V	515	Missense	distal	6	no	15.352	15.297	PhosphoSitePlus;EPSD	TCGA;COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	P38398	BRCA1	P31749	AKT1	T509	E515K	515	Missense	distal	6	no	15.352	15.421	PhosphoSitePlus;EPSD	TCGA;COSMIC	7.780	Up-regulation
AGC_Akt_AKT1_ST	P38398	BRCA1	P31749	AKT1	T509	H513Y	513	Missense	distal	4	no	15.352	15.292	PhosphoSitePlus;EPSD	TCGA;COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	P38398	BRCA1	P31749	AKT1	S510	E515Q	515	Missense	distal	5	no	13.497	13.486	EPSD	TCGA;COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	P38398	BRCA1	P31749	AKT1	S510	E515V	515	Missense	distal	5	no	13.497	13.470	EPSD	TCGA;COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	P38398	BRCA1	P31749	AKT1	S510	E515K	515	Missense	distal	5	no	13.497	13.531	EPSD	TCGA;COSMIC	7.780	Up-regulation
AGC_Akt_AKT1_ST	P38398	BRCA1	P31749	AKT1	S510	H513Y	513	Missense	distal	3	no	13.497	13.529	EPSD	TCGA;COSMIC	7.780	Up-regulation
AGC_Akt_AKT1_ST	P38398	BRCA1	P31749	AKT1	S615	R610M	610	Missense	distal	-5	no	16.200	11.677	EPSD	TCGA;COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	P38398	BRCA1	P31749	AKT1	S615	A622V	622	Missense	distal	7	no	16.200	16.195	EPSD	TCGA;COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	P38398	BRCA1	P31749	AKT1	S616	R610M	610	Missense	distal	-6	no	12.943	12.847	EPSD	TCGA;COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	P38398	BRCA1	P31749	AKT1	S616	A622V	622	Missense	distal	6	no	12.943	12.912	EPSD	TCGA;COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	P38398	BRCA1	P31749	AKT1	T617	R610M	610	Missense	distal	-7	no	10.620	10.348	EPSD	TCGA;COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	P38398	BRCA1	P31749	AKT1	T617	A622V	622	Missense	distal	5	no	10.620	10.611	EPSD	TCGA;COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	P38398	BRCA1	P31749	AKT1	S694	K690R	690	Missense	distal	-4	no	11.050	11.063	EPSD;PhosphoSitePlus	TCGA;COSMIC	7.780	Up-regulation
AGC_Akt_AKT1_ST	P38398	BRCA1	P31749	AKT1	S694	T688I	688	Missense	distal	-6	no	11.050	10.899	EPSD;PhosphoSitePlus	TCGA	7.780	Down-regulation
AGC_Akt_AKT1_ST	P38398	BRCA1	P31749	AKT1	T696	K690R	690	Missense	distal	-6	no	9.561	9.575	EPSD	TCGA;COSMIC	7.780	Up-regulation
AGC_Akt_AKT1_ST	P38398	BRCA1	P31749	AKT1	T710	G707R	707	Missense	distal	-3	no	4.289	11.045	EPSD	TCGA;COSMIC	7.780	Gain
AGC_Akt_AKT1_ST	P38398	BRCA1	P31749	AKT1	S767	E765Q	765	Missense	proximal	-2	no	9.166	8.874	EPSD	TCGA;COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	P38398	BRCA1	P31749	AKT1	S956	Q957E	957	Missense	proximal	1	no	8.809	8.863	EPSD	TCGA;COSMIC	7.780	Up-regulation
AGC_Akt_AKT1_ST	P38398	BRCA1	P31749	AKT1	S956	E962A	962	Missense	distal	6	no	8.809	8.785	EPSD	TCGA;COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	P38398	BRCA1	P31749	AKT1	S1211	E1210Q	1210	Missense	proximal	-1	no	9.013	9.006	EPSD	TCGA;COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	P38398	BRCA1	P31749	AKT1	S1211	E1214D	1214	Missense	distal	3	no	9.013	8.942	EPSD	TCGA;COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	P38398	BRCA1	P31749	AKT1	S1211	S1211F	1211	Missense	central	0	yes	9.013	0.000	EPSD	TCGA;COSMIC	7.780	Loss
AGC_Akt_AKT1_ST	P38398	BRCA1	P31749	AKT1	S1211	K1207N	1207	Missense	distal	-4	no	9.013	8.374	EPSD	TCGA;COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	P38398	BRCA1	P31749	AKT1	S1211	L1216V	1216	Missense	distal	5	no	9.013	9.020	EPSD	TCGA;COSMIC	7.780	Up-regulation
AGC_Akt_AKT1_ST	P38398	BRCA1	P31749	AKT1	T1246	V1247I	1247	Missense	proximal	1	no	11.072	10.824	EPSD	TCGA;COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	P38398	BRCA1	P31749	AKT1	T1246	T1242A	1242	Missense	distal	-4	no	11.072	10.294	EPSD	TCGA;COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	P38398	BRCA1	P31749	AKT1	T1246	H1244N	1244	Missense	proximal	-2	no	11.072	11.435	EPSD	TCGA;COSMIC	7.780	Up-regulation
AGC_Akt_AKT1_ST	P38398	BRCA1	P31749	AKT1	T1246	E1250K	1250	Missense	distal	4	no	11.072	10.971	EPSD	TCGA;COSMIC;GDSC	7.780	Down-regulation
AGC_Akt_AKT1_ST	P38398	BRCA1	P31749	AKT1	S1497	G1492R	1492	Missense	distal	-5	no	4.404	8.468	EPSD	TCGA;COSMIC	7.780	Gain
AGC_Akt_AKT1_ST	P38398	BRCA1	P31749	AKT1	T1675	R1670T	1670	Missense	distal	-5	no	11.680	7.950	EPSD	TCGA;COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	Q16584	MAP3K11	P31749	AKT1	S555	R550Q	550	Missense	distal	-5	no	8.655	4.428	EPSD	TCGA	7.780	Loss
AGC_Akt_AKT1_ST	Q16584	MAP3K11	P31749	AKT1	S555	S548F	548	Missense	distal	-7	no	8.655	8.378	EPSD	TCGA;ICGC;COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	Q16584	MAP3K11	P31749	AKT1	S555	R560W	560	Missense	distal	5	no	8.655	8.561	EPSD	TCGA;ICGC	7.780	Down-regulation
AGC_Akt_AKT1_ST	Q16584	MAP3K11	P31749	AKT1	S556	R560W	560	Missense	distal	4	no	7.690	7.937	EPSD	TCGA;ICGC	7.780	Gain
AGC_Akt_AKT1_ST	Q16584	MAP3K11	P31749	AKT1	S674	R669H	669	Missense	distal	-5	no	16.907	13.812	PhosphoSitePlus	TCGA;ICGC;COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	Q16584	MAP3K11	P31749	AKT1	T738	P743L	743	Missense	distal	5	no	11.934	11.920	EPSD	TCGA;COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	Q16584	MAP3K11	P31749	AKT1	S740	R747H	747	Missense	distal	7	no	9.218	9.147	EPSD	TCGA;COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	Q16584	MAP3K11	P31749	AKT1	S740	P743L	743	Missense	distal	3	no	9.218	9.202	EPSD	TCGA;COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	Q16584	MAP3K11	P31749	AKT1	T752	R747H	747	Missense	distal	-5	no	8.094	4.999	EPSD	TCGA;COSMIC	7.780	Loss
AGC_Akt_AKT1_ST	Q16584	MAP3K11	P31749	AKT1	T752	R757H	757	Missense	distal	5	no	8.094	8.020	EPSD	TCGA;COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	Q16584	MAP3K11	P31749	AKT1	S780	A784V	784	Missense	distal	4	no	8.768	8.824	EPSD	TCGA;ICGC;COSMIC	7.780	Up-regulation
AGC_Akt_AKT1_ST	Q16584	MAP3K11	P31749	AKT1	S780	R773C	773	Missense	distal	-7	no	8.768	8.289	EPSD	TCGA;ICGC;COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	Q16584	MAP3K11	P31749	AKT1	S780	R787L	787	Missense	distal	7	no	8.768	8.694	EPSD	TCGA;COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	Q16584	MAP3K11	P31749	AKT1	S780	P778S	778	Missense	proximal	-2	no	8.768	9.592	EPSD	TCGA;ICGC;COSMIC	7.780	Up-regulation
AGC_Akt_AKT1_ST	P55211	CASP9	P31749	AKT1	T181	R180H	180	Missense	proximal	-1	no	11.872	11.828	EPSD	TCGA;ICGC;COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	P55211	CASP9	P31749	AKT1	T181	E188D	188	Missense	distal	7	no	11.872	11.829	EPSD	TCGA;ICGC	7.780	Down-regulation
AGC_Akt_AKT1_ST	P55211	CASP9	P31749	AKT1	S183	R180H	180	Missense	distal	-3	no	17.682	12.983	EPSD	TCGA;ICGC;COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	P55211	CASP9	P31749	AKT1	S183	E188D	188	Missense	distal	5	no	17.682	17.640	EPSD	TCGA;ICGC	7.780	Down-regulation
AGC_Akt_AKT1_ST	P55211	CASP9	P31749	AKT1	S195	R193H	193	Missense	proximal	-2	no	12.401	11.540	EPSD	TCGA;ICGC;COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	P55211	CASP9	P31749	AKT1	S195	R191W	191	Missense	distal	-4	no	12.401	10.851	EPSD	TCGA;ICGC;COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	P55211	CASP9	P31749	AKT1	S195	R191Q	191	Missense	distal	-4	no	12.401	11.779	EPSD	TCGA	7.780	Down-regulation
AGC_Akt_AKT1_ST	P55211	CASP9	P31749	AKT1	S195	E188D	188	Missense	distal	-7	no	12.401	12.179	EPSD	TCGA;ICGC	7.780	Down-regulation
AGC_Akt_AKT1_ST	P55211	CASP9	P31749	AKT1	S196	R193H	193	Missense	distal	-3	no	15.219	10.520	PhosphoSitePlus	TCGA;ICGC;COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	P55211	CASP9	P31749	AKT1	S196	R191W	191	Missense	distal	-5	no	15.219	9.699	PhosphoSitePlus	TCGA;ICGC;COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	P55211	CASP9	P31749	AKT1	S196	R191Q	191	Missense	distal	-5	no	15.219	10.992	PhosphoSitePlus	TCGA	7.780	Down-regulation
AGC_Akt_AKT1_ST	O60343	TBC1D4	P31749	AKT1	S44	W39R	39	Missense	distal	-5	no	2.304	7.824	EPSD	TCGA;ICGC;COSMIC	7.780	Gain
AGC_Akt_AKT1_ST	O60343	TBC1D4	P31749	AKT1	S66	E61K	61	Missense	distal	-5	no	11.471	13.169	EPSD	TCGA;ICGC;COSMIC	7.780	Up-regulation
AGC_Akt_AKT1_ST	O60343	TBC1D4	P31749	AKT1	S318	R315W	315	Missense	distal	-3	no	15.833	6.892	PhosphoSitePlus;EPSD	TCGA;COSMIC	7.780	Loss
AGC_Akt_AKT1_ST	O60343	TBC1D4	P31749	AKT1	S318	R315Q	315	Missense	distal	-3	no	15.833	8.622	PhosphoSitePlus;EPSD	TCGA;ICGC;COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	O60343	TBC1D4	P31749	AKT1	S330	E328K	328	Missense	proximal	-2	no	10.553	11.212	EPSD	TCGA;ICGC;COSMIC	7.780	Up-regulation
AGC_Akt_AKT1_ST	O60343	TBC1D4	P31749	AKT1	S330	Q331H	331	Missense	proximal	1	no	10.553	10.526	EPSD	TCGA;ICGC;COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	O60343	TBC1D4	P31749	AKT1	S330	R336Q	336	Missense	distal	6	no	10.553	10.482	EPSD	TCGA;ICGC;COSMIC;CCLE	7.780	Down-regulation
AGC_Akt_AKT1_ST	O60343	TBC1D4	P31749	AKT1	S341	A342T	342	Missense	proximal	1	no	16.535	16.802	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	7.780	Up-regulation
AGC_Akt_AKT1_ST	O60343	TBC1D4	P31749	AKT1	S341	R336Q	336	Missense	distal	-5	no	16.535	12.308	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC;CCLE	7.780	Down-regulation
AGC_Akt_AKT1_ST	O60343	TBC1D4	P31749	AKT1	S485	L487V	487	Missense	proximal	2	no	9.754	9.761	EPSD	TCGA;ICGC;COSMIC	7.780	Up-regulation
AGC_Akt_AKT1_ST	O60343	TBC1D4	P31749	AKT1	T568	F575L	575	Missense	distal	7	no	12.685	12.692	EPSD;PhosphoSitePlus	TCGA;ICGC;CCLE	7.780	Up-regulation
AGC_Akt_AKT1_ST	O60343	TBC1D4	P31749	AKT1	S570	F575L	575	Missense	distal	5	no	9.973	9.979	EPSD;PhosphoSitePlus	TCGA;ICGC;CCLE	7.780	Up-regulation
AGC_Akt_AKT1_ST	O60343	TBC1D4	P31749	AKT1	S570	R577K	577	Missense	distal	7	no	9.973	9.965	EPSD;PhosphoSitePlus	TCGA	7.780	Down-regulation
AGC_Akt_AKT1_ST	O60343	TBC1D4	P31749	AKT1	S588	R594W	594	Missense	distal	6	no	14.745	14.587	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	O60343	TBC1D4	P31749	AKT1	S588	R585W	585	Missense	distal	-3	no	14.745	5.805	EPSD;PhosphoSitePlus	TCGA;ICGC	7.780	Loss
AGC_Akt_AKT1_ST	O60343	TBC1D4	P31749	AKT1	S597	R594W	594	Missense	distal	-3	no	12.000	3.059	EPSD	TCGA;ICGC;COSMIC	7.780	Loss
AGC_Akt_AKT1_ST	O60343	TBC1D4	P31749	AKT1	S673	C677R	677	Missense	distal	4	no	10.409	10.075	EPSD	TCGA;ICGC	7.780	Down-regulation
AGC_Akt_AKT1_ST	O60343	TBC1D4	P31749	AKT1	T749	K747E	747	Missense	proximal	-2	no	12.927	12.268	EPSD	TCGA;COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	O60343	TBC1D4	P31749	AKT1	T749	G743E	743	Missense	distal	-6	no	12.927	12.960	EPSD	TCGA	7.780	Up-regulation
AGC_Akt_AKT1_ST	O60343	TBC1D4	P31749	AKT1	T749	R748S	748	Missense	proximal	-1	no	12.927	12.916	EPSD	TCGA;COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	O60343	TBC1D4	P31749	AKT1	T749	R748M	748	Missense	proximal	-1	no	12.927	12.887	EPSD	TCGA;COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	O60343	TBC1D4	P31749	AKT1	S751	K747E	747	Missense	distal	-4	no	16.107	15.523	EPSD;PhosphoSitePlus	TCGA;COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	O60343	TBC1D4	P31749	AKT1	S751	R748S	748	Missense	distal	-3	no	16.107	8.331	EPSD;PhosphoSitePlus	TCGA;COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	O60343	TBC1D4	P31749	AKT1	S751	R748M	748	Missense	distal	-3	no	16.107	8.602	EPSD;PhosphoSitePlus	TCGA;COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	O60343	TBC1D4	P31749	AKT1	S771	R773W	773	Missense	proximal	2	no	11.807	11.352	EPSD	TCGA;COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	O60343	TBC1D4	P31749	AKT1	S771	V765A	765	Missense	distal	-6	no	11.807	11.828	EPSD	TCGA;COSMIC	7.780	Up-regulation
AGC_Akt_AKT1_ST	O60343	TBC1D4	P31749	AKT1	S782	P788S	788	Missense	distal	6	no	11.626	11.720	EPSD	TCGA;COSMIC	7.780	Up-regulation
AGC_Akt_AKT1_ST	O60343	TBC1D4	P31749	AKT1	S872	D868H	868	Missense	distal	-4	no	8.588	8.903	EPSD	TCGA;COSMIC	7.780	Up-regulation
AGC_Akt_AKT1_ST	O60343	TBC1D4	P31749	AKT1	S872	R873S	873	Missense	proximal	1	no	8.588	8.443	EPSD	TCGA;COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	O60343	TBC1D4	P31749	AKT1	S872	D878H	878	Missense	distal	6	no	8.588	8.617	EPSD	TCGA;COSMIC	7.780	Up-regulation
AGC_Akt_AKT1_ST	O60343	TBC1D4	P31749	AKT1	S1050	S1050L	1050	Missense	central	0	yes	10.165	0.000	EPSD	TCGA;COSMIC	7.780	Loss
AGC_Akt_AKT1_ST	O60343	TBC1D4	P31749	AKT1	S1207	E1203D	1203	Missense	distal	-4	no	10.377	9.601	EPSD	TCGA;COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	O60343	TBC1D4	P31749	AKT1	S1207	K1201E	1201	Missense	distal	-6	no	10.377	10.311	EPSD	TCGA;COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	Q2PPJ7	RALGAPA2	P31749	AKT1	S362	Q357H	357	Missense	distal	-5	no	8.057	9.190	EPSD	TCGA;ICGC;COSMIC	7.780	Up-regulation
AGC_Akt_AKT1_ST	Q2PPJ7	RALGAPA2	P31749	AKT1	S362	E356K	356	Missense	distal	-6	no	8.057	8.124	EPSD	TCGA;ICGC;COSMIC	7.780	Up-regulation
AGC_Akt_AKT1_ST	Q2PPJ7	RALGAPA2	P31749	AKT1	S364	Q357H	357	Missense	distal	-7	no	9.946	9.838	EPSD	TCGA;ICGC;COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	Q2PPJ7	RALGAPA2	P31749	AKT1	S373	S373I	373	Missense	central	0	yes	11.748	0.000	EPSD	TCGA;ICGC	7.780	Loss
AGC_Akt_AKT1_ST	Q2PPJ7	RALGAPA2	P31749	AKT1	S375	S373I	373	Missense	proximal	-2	no	9.734	8.493	EPSD	TCGA;ICGC	7.780	Down-regulation
AGC_Akt_AKT1_ST	Q2PPJ7	RALGAPA2	P31749	AKT1	S469	E462D	462	Missense	distal	-7	no	8.075	7.853	EPSD	TCGA;ICGC;COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	Q2PPJ7	RALGAPA2	P31749	AKT1	S469	S465R	465	Missense	distal	-4	no	8.075	8.161	EPSD	TCGA;ICGC;COSMIC	7.780	Up-regulation
AGC_Akt_AKT1_ST	Q2PPJ7	RALGAPA2	P31749	AKT1	S478	R483C	483	Missense	distal	5	no	8.596	8.470	EPSD	TCGA;ICGC;COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	Q2PPJ7	RALGAPA2	P31749	AKT1	S479	R483C	483	Missense	distal	4	no	7.731	8.065	EPSD	TCGA;ICGC;COSMIC	7.780	Gain
AGC_Akt_AKT1_ST	Q2PPJ7	RALGAPA2	P31749	AKT1	S480	R483C	483	Missense	distal	3	no	13.486	13.325	EPSD	TCGA;ICGC;COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	Q2PPJ7	RALGAPA2	P31749	AKT1	S480	F487C	487	Missense	distal	7	no	13.486	13.437	EPSD	TCGA;ICGC;COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	Q2PPJ7	RALGAPA2	P31749	AKT1	S486	R493T	493	Missense	distal	7	no	9.893	9.896	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	7.780	Up-regulation
AGC_Akt_AKT1_ST	Q2PPJ7	RALGAPA2	P31749	AKT1	S486	M491I	491	Missense	distal	5	no	9.893	9.853	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	Q2PPJ7	RALGAPA2	P31749	AKT1	S486	R493K	493	Missense	distal	7	no	9.893	9.886	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	Q2PPJ7	RALGAPA2	P31749	AKT1	S486	R483C	483	Missense	distal	-3	no	9.893	3.719	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	7.780	Loss
AGC_Akt_AKT1_ST	Q2PPJ7	RALGAPA2	P31749	AKT1	S486	T488I	488	Missense	proximal	2	no	9.893	9.311	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	Q2PPJ7	RALGAPA2	P31749	AKT1	S486	F487C	487	Missense	proximal	1	no	9.893	9.492	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	Q2PPJ7	RALGAPA2	P31749	AKT1	T497	G494R	494	Missense	distal	-3	no	3.455	10.211	EPSD	TCGA;ICGC	7.780	Gain
AGC_Akt_AKT1_ST	Q2PPJ7	RALGAPA2	P31749	AKT1	S696	L697F	697	Missense	proximal	1	no	11.600	11.519	EPSD	TCGA;ICGC;COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	Q2PPJ7	RALGAPA2	P31749	AKT1	S696	R700Q	700	Missense	distal	4	no	11.600	11.723	EPSD	TCGA;ICGC;COSMIC	7.780	Up-regulation
AGC_Akt_AKT1_ST	Q2PPJ7	RALGAPA2	P31749	AKT1	S698	L697F	697	Missense	proximal	-1	no	10.338	10.332	EPSD	TCGA;ICGC;COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	Q2PPJ7	RALGAPA2	P31749	AKT1	S698	R700Q	700	Missense	proximal	2	no	10.338	10.221	EPSD	TCGA;ICGC;COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	Q2PPJ7	RALGAPA2	P31749	AKT1	S713	E707K	707	Missense	distal	-6	no	10.632	10.698	EPSD	TCGA;ICGC;COSMIC	7.780	Up-regulation
AGC_Akt_AKT1_ST	Q2PPJ7	RALGAPA2	P31749	AKT1	S713	A714T	714	Missense	proximal	1	no	10.632	10.899	EPSD	TCGA;ICGC;COSMIC	7.780	Up-regulation
AGC_Akt_AKT1_ST	Q2PPJ7	RALGAPA2	P31749	AKT1	T715	A714T	714	Missense	proximal	-1	no	14.221	14.247	PhosphoSitePlus;EPSD	TCGA;ICGC;COSMIC	7.780	Up-regulation
AGC_Akt_AKT1_ST	Q2PPJ7	RALGAPA2	P31749	AKT1	S717	A714T	714	Missense	distal	-3	no	10.425	9.706	EPSD	TCGA;ICGC;COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	Q2PPJ7	RALGAPA2	P31749	AKT1	S766	S764R	764	Missense	proximal	-2	no	11.428	11.240	EPSD	TCGA;ICGC;COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	Q2PPJ7	RALGAPA2	P31749	AKT1	S766	L762F	762	Missense	distal	-4	no	11.428	11.384	EPSD	TCGA;ICGC;COSMIC;GDSC;CCLE	7.780	Down-regulation
AGC_Akt_AKT1_ST	Q2PPJ7	RALGAPA2	P31749	AKT1	S766	P771L	771	Missense	distal	5	no	11.428	11.415	EPSD	TCGA;ICGC;COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	Q2PPJ7	RALGAPA2	P31749	AKT1	T767	S764R	764	Missense	distal	-3	no	2.761	10.537	EPSD	TCGA;ICGC;COSMIC	7.780	Gain
AGC_Akt_AKT1_ST	Q2PPJ7	RALGAPA2	P31749	AKT1	S768	S764R	764	Missense	distal	-4	no	8.956	9.041	EPSD	TCGA;ICGC;COSMIC	7.780	Up-regulation
AGC_Akt_AKT1_ST	Q2PPJ7	RALGAPA2	P31749	AKT1	S768	L762F	762	Missense	distal	-6	no	8.956	8.932	EPSD	TCGA;ICGC;COSMIC;GDSC;CCLE	7.780	Down-regulation
AGC_Akt_AKT1_ST	Q2PPJ7	RALGAPA2	P31749	AKT1	S768	P771L	771	Missense	distal	3	no	8.956	8.939	EPSD	TCGA;ICGC;COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	Q2PPJ7	RALGAPA2	P31749	AKT1	S820	R817Q	817	Missense	distal	-3	no	9.942	2.731	EPSD	TCGA;ICGC;COSMIC	7.780	Loss
AGC_Akt_AKT1_ST	Q2PPJ7	RALGAPA2	P31749	AKT1	S821	R817Q	817	Missense	distal	-4	no	11.519	10.898	EPSD	TCGA;ICGC;COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	Q2PPJ7	RALGAPA2	P31749	AKT1	S844	S846R	846	Missense	proximal	2	no	16.116	15.944	EPSD	TCGA;ICGC;COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	Q2PPJ7	RALGAPA2	P31749	AKT1	S844	E845K	845	Missense	proximal	1	no	16.116	16.279	EPSD	TCGA;ICGC;COSMIC	7.780	Up-regulation
AGC_Akt_AKT1_ST	Q2PPJ7	RALGAPA2	P31749	AKT1	S844	S844G	844	Missense	central	0	yes	16.116	0.000	EPSD	TCGA;ICGC	7.780	Loss
AGC_Akt_AKT1_ST	Q2PPJ7	RALGAPA2	P31749	AKT1	S846	S846R	846	Missense	central	0	yes	11.253	0.000	EPSD	TCGA;ICGC;COSMIC	7.780	Loss
AGC_Akt_AKT1_ST	Q2PPJ7	RALGAPA2	P31749	AKT1	S846	E845K	845	Missense	proximal	-1	no	11.253	11.274	EPSD	TCGA;ICGC;COSMIC	7.780	Up-regulation
AGC_Akt_AKT1_ST	Q2PPJ7	RALGAPA2	P31749	AKT1	S846	S844G	844	Missense	proximal	-2	no	11.253	10.558	EPSD	TCGA;ICGC	7.780	Down-regulation
AGC_Akt_AKT1_ST	Q2PPJ7	RALGAPA2	P31749	AKT1	S849	S846R	846	Missense	distal	-3	no	3.734	11.510	EPSD	TCGA;ICGC;COSMIC	7.780	Gain
AGC_Akt_AKT1_ST	Q2PPJ7	RALGAPA2	P31749	AKT1	T1646	A1650T	1650	Missense	distal	4	no	8.788	8.659	EPSD	TCGA;ICGC;COSMIC;GDSC;CCLE	7.780	Down-regulation
AGC_Akt_AKT1_ST	Q2PPJ7	RALGAPA2	P31749	AKT1	T1646	R1641C	1641	Missense	distal	-5	no	8.788	4.711	EPSD	TCGA;ICGC;COSMIC	7.780	Loss
AGC_Akt_AKT1_ST	Q3V6T2	CCDC88A	P31749	AKT1	T15	Q12H	12	Missense	distal	-3	no	5.542	8.055	EPSD	TCGA;ICGC;COSMIC	7.780	Gain
AGC_Akt_AKT1_ST	Q3V6T2	CCDC88A	P31749	AKT1	S245	L249V	249	Missense	distal	4	no	11.676	11.667	EPSD	TCGA;ICGC;COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	Q3V6T2	CCDC88A	P31749	AKT1	S913	E909Q	909	Missense	distal	-4	no	8.703	8.680	EPSD	TCGA;ICGC;COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	Q3V6T2	CCDC88A	P31749	AKT1	S913	R908C	908	Missense	distal	-5	no	8.703	4.627	EPSD	TCGA;ICGC;COSMIC	7.780	Loss
AGC_Akt_AKT1_ST	Q3V6T2	CCDC88A	P31749	AKT1	T1673	H1668R	1668	Missense	distal	-5	no	4.784	7.879	EPSD	TCGA;ICGC;COSMIC	7.780	Gain
AGC_Akt_AKT1_ST	Q3V6T2	CCDC88A	P31749	AKT1	S1675	H1668R	1668	Missense	distal	-7	no	7.705	8.007	EPSD	TCGA;ICGC;COSMIC	7.780	Gain
AGC_Akt_AKT1_ST	Q3V6T2	CCDC88A	P31749	AKT1	T1764	S1768Y	1768	Missense	distal	4	no	8.207	8.343	EPSD	TCGA;COSMIC	7.780	Up-regulation
AGC_Akt_AKT1_ST	P42345	MTOR	P31749	AKT1	T10	G5R	5	Missense	distal	-5	no	6.758	10.823	EPSD	TCGA;ICGC;COSMIC	7.780	Gain
AGC_Akt_AKT1_ST	P42345	MTOR	P31749	AKT1	T314	R311H	311	Missense	distal	-3	no	11.505	6.806	EPSD	TCGA;ICGC;COSMIC	7.780	Loss
AGC_Akt_AKT1_ST	P42345	MTOR	P31749	AKT1	T314	R311C	311	Missense	distal	-3	no	11.505	5.331	EPSD	TCGA;ICGC;COSMIC	7.780	Loss
AGC_Akt_AKT1_ST	P42345	MTOR	P31749	AKT1	T631	R624H	624	Missense	distal	-7	no	10.213	9.912	EPSD	TCGA;ICGC;COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	P42345	MTOR	P31749	AKT1	S720	R717Q	717	Missense	distal	-3	no	10.171	2.960	EPSD	TCGA;ICGC;COSMIC	7.780	Loss
AGC_Akt_AKT1_ST	P42345	MTOR	P31749	AKT1	S720	N722D	722	Missense	proximal	2	no	10.171	9.841	EPSD	TCGA;ICGC;COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	P42345	MTOR	P31749	AKT1	S913	R910Q	910	Missense	distal	-3	no	11.968	4.757	EPSD	TCGA;ICGC;COSMIC	7.780	Loss
AGC_Akt_AKT1_ST	P42345	MTOR	P31749	AKT1	S913	V915F	915	Missense	proximal	2	no	11.968	11.929	EPSD	TCGA;ICGC;COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	P42345	MTOR	P31749	AKT1	S1821	A1823T	1823	Missense	proximal	2	no	11.710	12.011	EPSD	TCGA;ICGC;COSMIC	7.780	Up-regulation
AGC_Akt_AKT1_ST	P42345	MTOR	P31749	AKT1	S1893	R1896Q	1896	Missense	distal	3	no	12.435	12.379	EPSD	TCGA;ICGC;COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	P42345	MTOR	P31749	AKT1	S1893	R1890C	1890	Missense	distal	-3	no	12.435	6.262	EPSD	TCGA;ICGC;COSMIC;CCLE	7.780	Loss
AGC_Akt_AKT1_ST	P42345	MTOR	P31749	AKT1	S1893	N1898S	1898	Missense	distal	5	no	12.435	12.470	EPSD	TCGA;ICGC;COSMIC	7.780	Up-regulation
AGC_Akt_AKT1_ST	P42345	MTOR	P31749	AKT1	S1893	F1888L	1888	Missense	distal	-5	no	12.435	11.831	EPSD	TCGA;ICGC;COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	P42345	MTOR	P31749	AKT1	S1893	F1888V	1888	Missense	distal	-5	no	12.435	11.642	EPSD	TCGA;ICGC;COSMIC;GDSC;CCLE	7.780	Down-regulation
AGC_Akt_AKT1_ST	P42345	MTOR	P31749	AKT1	T1948	V1953L	1953	Missense	distal	5	no	10.263	10.256	EPSD	TCGA;ICGC;COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	P42345	MTOR	P31749	AKT1	T1948	T1948M	1948	Missense	central	0	yes	10.263	0.000	EPSD	TCGA;ICGC;COSMIC;GDSC;CCLE	7.780	Loss
AGC_Akt_AKT1_ST	P42345	MTOR	P31749	AKT1	S1982	T1977K	1977	Missense	distal	-5	no	7.623	8.956	EPSD	TCGA;ICGC;COSMIC	7.780	Gain
AGC_Akt_AKT1_ST	P42345	MTOR	P31749	AKT1	S1982	T1977R	1977	Missense	distal	-5	no	7.623	11.353	EPSD	TCGA;ICGC;COSMIC	7.780	Gain
AGC_Akt_AKT1_ST	P42345	MTOR	P31749	AKT1	S2155	R2152C	2152	Missense	distal	-3	no	8.471	2.297	EPSD	TCGA;ICGC;COSMIC;GDSC;CCLE	7.780	Loss
AGC_Akt_AKT1_ST	P42345	MTOR	P31749	AKT1	S2155	S2155F	2155	Missense	central	0	yes	8.471	0.000	EPSD	TCGA;ICGC;COSMIC	7.780	Loss
AGC_Akt_AKT1_ST	P42345	MTOR	P31749	AKT1	T2173	P2169S	2169	Missense	distal	-4	no	15.593	16.329	EPSD	TCGA	7.780	Up-regulation
AGC_Akt_AKT1_ST	P42345	MTOR	P31749	AKT1	T2173	L2172M	2172	Missense	proximal	-1	no	15.593	15.592	EPSD	TCGA;ICGC;COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	P42345	MTOR	P31749	AKT1	S2221	S2215Y	2215	Missense	distal	-6	no	8.739	8.680	EPSD	TCGA;ICGC;COSMIC;CCLE	7.780	Down-regulation
AGC_Akt_AKT1_ST	P42345	MTOR	P31749	AKT1	S2221	S2215F	2215	Missense	distal	-6	no	8.739	8.664	EPSD	TCGA;ICGC;COSMIC;GDSC;CCLE	7.780	Down-regulation
AGC_Akt_AKT1_ST	P42345	MTOR	P31749	AKT1	S2221	Q2223K	2223	Missense	proximal	2	no	8.739	9.044	EPSD	TCGA;ICGC;COSMIC	7.780	Up-regulation
AGC_Akt_AKT1_ST	P42345	MTOR	P31749	AKT1	S2221	I2228T	2228	Missense	distal	7	no	8.739	8.846	EPSD	TCGA;ICGC;COSMIC	7.780	Up-regulation
AGC_Akt_AKT1_ST	P42345	MTOR	P31749	AKT1	S2221	L2216P	2216	Missense	distal	-5	no	8.739	8.855	EPSD	TCGA;ICGC;COSMIC	7.780	Up-regulation
AGC_Akt_AKT1_ST	P42345	MTOR	P31749	AKT1	S2221	Y2225C	2225	Missense	distal	4	no	8.739	8.948	EPSD	TCGA;ICGC;COSMIC	7.780	Up-regulation
AGC_Akt_AKT1_ST	P42345	MTOR	P31749	AKT1	T2444	R2441Q	2441	Missense	distal	-3	no	12.611	5.399	EPSD	TCGA;ICGC;COSMIC	7.780	Loss
AGC_Akt_AKT1_ST	P42345	MTOR	P31749	AKT1	T2446	R2441Q	2441	Missense	distal	-5	no	15.598	11.371	PhosphoSitePlus;EPSD	TCGA;ICGC;COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	P42345	MTOR	P31749	AKT1	S2448	R2441Q	2441	Missense	distal	-7	no	17.580	17.386	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	P42345	MTOR	P31749	AKT1	T2473	T2471M	2471	Missense	proximal	-2	no	8.095	7.321	EPSD	TCGA;COSMIC;GDSC;CCLE	7.780	Loss
AGC_Akt_AKT1_ST	P42345	MTOR	P31749	AKT1	S2514	D2516Y	2516	Missense	proximal	2	no	10.472	10.699	EPSD	TCGA;ICGC;COSMIC	7.780	Up-regulation
AGC_Akt_AKT1_ST	P42345	MTOR	P31749	AKT1	S2514	D2512Y	2512	Missense	proximal	-2	no	10.472	10.943	EPSD	TCGA;ICGC;COSMIC	7.780	Up-regulation
AGC_Akt_AKT1_ST	P35232	PHB	P31749	AKT1	S151	E156K	156	Missense	distal	5	no	11.967	12.001	EPSD	TCGA;ICGC;COSMIC	7.780	Up-regulation
AGC_Akt_AKT1_ST	P35232	PHB	P31749	AKT1	S151	D152E	152	Missense	proximal	1	no	11.967	12.084	EPSD	TCGA;ICGC;COSMIC	7.780	Up-regulation
AGC_Akt_AKT1_ST	Q13045	FLII	P31749	AKT1	S90	R87Q	87	Missense	distal	-3	no	10.721	3.509	EPSD	TCGA;ICGC;COSMIC	7.780	Loss
AGC_Akt_AKT1_ST	Q13045	FLII	P31749	AKT1	S406	G404V	404	Missense	proximal	-2	no	8.560	8.064	EPSD	TCGA;ICGC;COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	Q13045	FLII	P31749	AKT1	S406	A403V	403	Missense	distal	-3	no	8.560	7.997	EPSD	TCGA;ICGC;COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	Q13045	FLII	P31749	AKT1	S406	R401W	401	Missense	distal	-5	no	8.560	3.040	EPSD	TCGA;ICGC;CCLE	7.780	Loss
AGC_Akt_AKT1_ST	Q13045	FLII	P31749	AKT1	S436	R431W	431	Missense	distal	-5	no	16.954	11.435	PhosphoSitePlus	TCGA;COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	Q13045	FLII	P31749	AKT1	S436	R432K	432	Missense	distal	-4	no	16.954	16.941	PhosphoSitePlus	TCGA;COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	Q13045	FLII	P31749	AKT1	S436	D440G	440	Missense	distal	4	no	16.954	16.903	PhosphoSitePlus	TCGA	7.780	Down-regulation
AGC_Akt_AKT1_ST	Q13045	FLII	P31749	AKT1	T818	L823P	823	Missense	distal	5	no	14.407	14.421	EPSD	TCGA;COSMIC	7.780	Up-regulation
AGC_Akt_AKT1_ST	Q13045	FLII	P31749	AKT1	T826	L823P	823	Missense	distal	-3	no	9.376	9.730	EPSD	TCGA;COSMIC	7.780	Up-regulation
AGC_Akt_AKT1_ST	Q13045	FLII	P31749	AKT1	T826	V830A	830	Missense	distal	4	no	9.376	9.320	EPSD	TCGA	7.780	Down-regulation
AGC_Akt_AKT1_ST	Q9UGI0	ZRANB1	P31749	AKT1	S78	S78Y	78	Missense	central	0	yes	15.915	0.000	PhosphoSitePlus;EPSD	TCGA;ICGC	7.780	Loss
AGC_Akt_AKT1_ST	Q9UGI0	ZRANB1	P31749	AKT1	S78	R75M	75	Missense	distal	-3	no	15.915	8.409	PhosphoSitePlus;EPSD	TCGA;ICGC	7.780	Down-regulation
AGC_Akt_AKT1_ST	Q9UGI0	ZRANB1	P31749	AKT1	S115	Q121R	121	Missense	distal	6	no	11.781	11.852	EPSD	TCGA;ICGC;COSMIC	7.780	Up-regulation
AGC_Akt_AKT1_ST	Q9UGI0	ZRANB1	P31749	AKT1	T117	Q121R	121	Missense	distal	4	no	17.579	17.456	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	Q9UGI0	ZRANB1	P31749	AKT1	S119	Q121R	121	Missense	proximal	2	no	12.143	12.260	EPSD	TCGA;ICGC;COSMIC	7.780	Up-regulation
AGC_Akt_AKT1_ST	Q9UGI0	ZRANB1	P31749	AKT1	S209	S206R	206	Missense	distal	-3	no	6.523	14.299	EPSD	TCGA;ICGC;COSMIC	7.780	Gain
AGC_Akt_AKT1_ST	Q9UGI0	ZRANB1	P31749	AKT1	T552	K546N	546	Missense	distal	-6	no	9.258	9.191	EPSD	TCGA;ICGC;COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	Q9UGI0	ZRANB1	P31749	AKT1	T552	R557Q	557	Missense	distal	5	no	9.258	9.207	EPSD	TCGA;ICGC;COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	Q9UGI0	ZRANB1	P31749	AKT1	T694	R688Q	688	Missense	distal	-6	no	11.373	11.289	EPSD	TCGA;ICGC;COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	Q9UGI0	ZRANB1	P31749	AKT1	T694	E700Q	700	Missense	distal	6	no	11.373	11.360	EPSD	TCGA;ICGC;COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	Q9UGI0	ZRANB1	P31749	AKT1	T694	R688L	688	Missense	distal	-6	no	11.373	11.288	EPSD	TCGA;ICGC	7.780	Down-regulation
AGC_Akt_AKT1_ST	Q13043	STK4	P31749	AKT1	S21	K16R	16	Missense	distal	-5	no	7.766	10.163	EPSD	TCGA;ICGC;COSMIC	7.780	Gain
AGC_Akt_AKT1_ST	Q13043	STK4	P31749	AKT1	T120	R117Q	117	Missense	distal	-3	no	13.999	6.788	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC;GDSC;CCLE	7.780	Loss
AGC_Akt_AKT1_ST	Q13043	STK4	P31749	AKT1	T120	T120M	120	Missense	central	0	yes	13.999	0.000	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	7.780	Loss
AGC_Akt_AKT1_ST	Q13043	STK4	P31749	AKT1	T120	R115Q	115	Missense	distal	-5	no	13.999	9.772	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	Q13043	STK4	P31749	AKT1	T122	T128A	128	Missense	distal	6	no	11.495	11.392	EPSD	TCGA;ICGC;COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	Q13043	STK4	P31749	AKT1	T122	R117Q	117	Missense	distal	-5	no	11.495	7.267	EPSD	TCGA;ICGC;COSMIC;GDSC;CCLE	7.780	Loss
AGC_Akt_AKT1_ST	Q13043	STK4	P31749	AKT1	T122	T120M	120	Missense	proximal	-2	no	11.495	10.721	EPSD	TCGA;ICGC;COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	Q13043	STK4	P31749	AKT1	T122	R115Q	115	Missense	distal	-7	no	11.495	11.300	EPSD	TCGA;ICGC;COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	Q13043	STK4	P31749	AKT1	T243	P240R	240	Missense	distal	-3	no	3.837	10.477	EPSD	TCGA;COSMIC	7.780	Gain
AGC_Akt_AKT1_ST	Q13043	STK4	P31749	AKT1	S307	D313Y	313	Missense	distal	6	no	11.863	11.924	EPSD	TCGA	7.780	Up-regulation
AGC_Akt_AKT1_ST	Q13043	STK4	P31749	AKT1	S307	Q305H	305	Missense	proximal	-2	no	11.863	11.515	EPSD	TCGA;COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	Q13043	STK4	P31749	AKT1	T387	E386K	386	Missense	proximal	-1	no	12.521	12.542	EPSD;PhosphoSitePlus	TCGA;COSMIC	7.780	Up-regulation
AGC_Akt_AKT1_ST	Q99683	MAP3K5	P31749	AKT1	S83	R80Q	80	Missense	distal	-3	no	15.754	8.543	PhosphoSitePlus	TCGA	7.780	Down-regulation
AGC_Akt_AKT1_ST	Q99683	MAP3K5	P31749	AKT1	S613	S615C	615	Missense	proximal	2	no	10.419	9.594	EPSD	TCGA;COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	Q99683	MAP3K5	P31749	AKT1	S613	S607C	607	Missense	distal	-6	no	10.419	10.273	EPSD	TCGA;COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	Q99683	MAP3K5	P31749	AKT1	S613	S613N	613	Missense	central	0	yes	10.419	0.000	EPSD	TCGA;COSMIC	7.780	Loss
AGC_Akt_AKT1_ST	Q99683	MAP3K5	P31749	AKT1	S613	E618K	618	Missense	distal	5	no	10.419	10.453	EPSD	TCGA;ICGC;COSMIC	7.780	Up-regulation
AGC_Akt_AKT1_ST	Q99683	MAP3K5	P31749	AKT1	S613	R620I	620	Missense	distal	7	no	10.419	10.314	EPSD	TCGA;ICGC;COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	Q99683	MAP3K5	P31749	AKT1	S613	V609F	609	Missense	distal	-4	no	10.419	10.345	EPSD	TCGA;ICGC;COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	Q99683	MAP3K5	P31749	AKT1	S615	S615C	615	Missense	central	0	yes	9.337	0.000	EPSD	TCGA;COSMIC	7.780	Loss
AGC_Akt_AKT1_ST	Q99683	MAP3K5	P31749	AKT1	S615	S613N	613	Missense	proximal	-2	no	9.337	8.652	EPSD	TCGA;COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	Q99683	MAP3K5	P31749	AKT1	S615	E618K	618	Missense	distal	3	no	9.337	9.381	EPSD	TCGA;ICGC;COSMIC	7.780	Up-regulation
AGC_Akt_AKT1_ST	Q99683	MAP3K5	P31749	AKT1	S615	R620I	620	Missense	distal	5	no	9.337	9.233	EPSD	TCGA;ICGC;COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	Q99683	MAP3K5	P31749	AKT1	S615	V609F	609	Missense	distal	-6	no	9.337	9.338	EPSD	TCGA;ICGC;COSMIC	7.780	Up-regulation
AGC_Akt_AKT1_ST	Q99683	MAP3K5	P31749	AKT1	S966	S966F	966	Missense	central	0	yes	11.671	0.000	EPSD	TCGA;COSMIC;CCLE	7.780	Loss
AGC_Akt_AKT1_ST	Q99683	MAP3K5	P31749	AKT1	S966	P968L	968	Missense	proximal	2	no	11.671	11.461	EPSD	TCGA;COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	Q99683	MAP3K5	P31749	AKT1	T1059	V1066M	1066	Missense	distal	7	no	11.135	11.131	EPSD	TCGA;COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	Q99683	MAP3K5	P31749	AKT1	T1059	T1059M	1059	Missense	central	0	yes	11.135	0.000	EPSD	TCGA;COSMIC	7.780	Loss
AGC_Akt_AKT1_ST	Q99683	MAP3K5	P31749	AKT1	T1108	T1108I	1108	Missense	central	0	yes	8.579	0.000	EPSD	TCGA;ICGC	7.780	Loss
AGC_Akt_AKT1_ST	Q99683	MAP3K5	P31749	AKT1	T1108	R1103Q	1103	Missense	distal	-5	no	8.579	4.352	EPSD	TCGA;ICGC;COSMIC	7.780	Loss
AGC_Akt_AKT1_ST	Q99683	MAP3K5	P31749	AKT1	T1108	T1101I	1101	Missense	distal	-7	no	8.579	8.157	EPSD	TCGA;COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	O43464	HTRA2	P31749	AKT1	S13	R15W	15	Missense	proximal	2	no	10.311	9.856	EPSD	TCGA;ICGC;COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	O43464	HTRA2	P31749	AKT1	S13	W12C	12	Missense	proximal	-1	no	10.311	10.301	EPSD	TCGA;ICGC;COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	O43464	HTRA2	P31749	AKT1	S41	A37T	37	Missense	distal	-4	no	9.709	10.487	EPSD	TCGA;ICGC;COSMIC	7.780	Up-regulation
AGC_Akt_AKT1_ST	O43464	HTRA2	P31749	AKT1	S96	T90I	90	Missense	distal	-6	no	17.614	17.463	EPSD	TCGA;ICGC;COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	O43464	HTRA2	P31749	AKT1	S212	R207G	207	Missense	distal	-5	no	16.004	11.940	PhosphoSitePlus	TCGA;ICGC;COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	O43464	HTRA2	P31749	AKT1	S212	V219L	219	Missense	distal	7	no	16.004	15.993	PhosphoSitePlus	TCGA;ICGC;COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	O43464	HTRA2	P31749	AKT1	S350	G353R	353	Missense	distal	3	no	9.506	9.581	EPSD	TCGA;COSMIC;GDSC;CCLE	7.780	Up-regulation
AGC_Akt_AKT1_ST	O43464	HTRA2	P31749	AKT1	S435	R432Q	432	Missense	distal	-3	no	12.291	5.080	EPSD	TCGA;COSMIC	7.780	Loss
AGC_Akt_AKT1_ST	O43464	HTRA2	P31749	AKT1	S435	A430V	430	Missense	distal	-5	no	12.291	11.831	EPSD	TCGA	7.780	Down-regulation
AGC_Akt_AKT1_ST	Q9UN36	NDRG2	P31749	AKT1	S346	R345H	345	Missense	proximal	-1	no	13.688	13.643	EPSD	TCGA	7.780	Down-regulation
AGC_Akt_AKT1_ST	Q9UN36	NDRG2	P31749	AKT1	T348	R345H	345	Missense	distal	-3	no	15.892	11.193	PhosphoSitePlus;EPSD	TCGA	7.780	Down-regulation
AGC_Akt_AKT1_ST	Q9UN36	NDRG2	P31749	AKT1	S350	R345H	345	Missense	distal	-5	no	19.104	16.009	EPSD	TCGA	7.780	Down-regulation
AGC_Akt_AKT1_ST	Q9UN36	NDRG2	P31749	AKT1	S352	S359Y	359	Missense	distal	7	no	11.781	11.739	EPSD	TCGA;ICGC	7.780	Down-regulation
AGC_Akt_AKT1_ST	Q9UN36	NDRG2	P31749	AKT1	S352	R345H	345	Missense	distal	-7	no	11.781	11.480	EPSD	TCGA	7.780	Down-regulation
AGC_Akt_AKT1_ST	Q9UN36	NDRG2	P31749	AKT1	S359	S359Y	359	Missense	central	0	yes	7.976	0.000	EPSD	TCGA;ICGC	7.780	Loss
AGC_Akt_AKT1_ST	O95999	BCL10	P31749	AKT1	T52	S56Y	56	Missense	distal	4	no	11.782	11.918	EPSD	TCGA;ICGC;COSMIC	7.780	Up-regulation
AGC_Akt_AKT1_ST	O95999	BCL10	P31749	AKT1	S138	F143L	143	Missense	distal	5	no	14.006	14.012	EPSD	TCGA;ICGC;COSMIC	7.780	Up-regulation
AGC_Akt_AKT1_ST	O95999	BCL10	P31749	AKT1	S138	D139N	139	Missense	proximal	1	no	14.006	14.130	EPSD	TCGA;ICGC;COSMIC	7.780	Up-regulation
AGC_Akt_AKT1_ST	O95999	BCL10	P31749	AKT1	S227	R228C	228	Missense	proximal	1	no	7.837	7.309	EPSD	TCGA;ICGC;COSMIC	7.780	Loss
AGC_Akt_AKT1_ST	O95999	BCL10	P31749	AKT1	T229	R228C	228	Missense	proximal	-1	no	12.071	12.000	EPSD	TCGA;ICGC;COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	O95999	BCL10	P31749	AKT1	S231	R228C	228	Missense	distal	-3	no	18.236	12.062	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	P35240	NF2	P31749	AKT1	S13	A6V	6	Missense	distal	-7	no	9.220	9.092	EPSD	TCGA;ICGC;COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	P35240	NF2	P31749	AKT1	T230	R225W	225	Missense	distal	-5	no	10.354	4.834	EPSD;PhosphoSitePlus	TCGA	7.780	Loss
AGC_Akt_AKT1_ST	P35240	NF2	P31749	AKT1	T230	T230I	230	Missense	central	0	yes	10.354	0.000	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	7.780	Loss
AGC_Akt_AKT1_ST	P35240	NF2	P31749	AKT1	S265	F271L	271	Missense	distal	6	no	9.943	9.959	EPSD	TCGA;ICGC	7.780	Up-regulation
AGC_Akt_AKT1_ST	P35240	NF2	P31749	AKT1	S267	F271L	271	Missense	distal	4	no	8.370	8.362	EPSD	TCGA;ICGC	7.780	Down-regulation
AGC_Akt_AKT1_ST	P35240	NF2	P31749	AKT1	S315	A313S	313	Missense	proximal	-2	no	11.067	11.519	PhosphoSitePlus;EPSD	TCGA;ICGC;COSMIC	7.780	Up-regulation
AGC_Akt_AKT1_ST	P35240	NF2	P31749	AKT1	S571	E564Q	564	Missense	distal	-7	no	11.247	11.258	EPSD	TCGA;ICGC;COSMIC	7.780	Up-regulation
AGC_Akt_AKT1_ST	P35240	NF2	P31749	AKT1	S584	F591L	591	Missense	distal	7	no	8.521	8.529	EPSD	TCGA;COSMIC	7.780	Up-regulation
AGC_Akt_AKT1_ST	Q92547	TOPBP1	P31749	AKT1	S142	L139V	139	Missense	distal	-3	no	8.324	8.453	EPSD	TCGA;ICGC;COSMIC	7.780	Up-regulation
AGC_Akt_AKT1_ST	Q92547	TOPBP1	P31749	AKT1	S471	N469T	469	Missense	proximal	-2	no	9.143	9.762	EPSD	TCGA;ICGC	7.780	Up-regulation
AGC_Akt_AKT1_ST	Q92547	TOPBP1	P31749	AKT1	S584	K581R	581	Missense	distal	-3	no	7.389	11.909	EPSD	TCGA;ICGC;COSMIC	7.780	Gain
AGC_Akt_AKT1_ST	Q92547	TOPBP1	P31749	AKT1	T779	N784S	784	Missense	distal	5	no	8.056	8.091	EPSD	TCGA;ICGC;COSMIC	7.780	Up-regulation
AGC_Akt_AKT1_ST	Q92547	TOPBP1	P31749	AKT1	S788	N784S	784	Missense	distal	-4	no	10.424	10.991	EPSD	TCGA;ICGC;COSMIC	7.780	Up-regulation
AGC_Akt_AKT1_ST	Q92547	TOPBP1	P31749	AKT1	S836	K831R	831	Missense	distal	-5	no	6.699	9.096	EPSD	TCGA;ICGC;COSMIC	7.780	Gain
AGC_Akt_AKT1_ST	Q92547	TOPBP1	P31749	AKT1	S860	V866F	866	Missense	distal	6	no	12.893	12.887	EPSD	TCGA;ICGC;COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	Q92547	TOPBP1	P31749	AKT1	S860	T861M	861	Missense	proximal	1	no	12.893	12.637	EPSD	TCGA;ICGC;COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	Q92547	TOPBP1	P31749	AKT1	S1159	P1164A	1164	Missense	distal	5	no	15.377	15.379	PhosphoSitePlus	TCGA;ICGC;COSMIC	7.780	Up-regulation
AGC_Akt_AKT1_ST	Q92547	TOPBP1	P31749	AKT1	S1159	R1154T	1154	Missense	distal	-5	no	15.377	11.648	PhosphoSitePlus	TCGA;ICGC;COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	Q92547	TOPBP1	P31749	AKT1	S1216	I1215M	1215	Missense	proximal	-1	no	8.218	8.239	EPSD	TCGA;ICGC;COSMIC	7.780	Up-regulation
AGC_Akt_AKT1_ST	Q92547	TOPBP1	P31749	AKT1	T1256	H1261Y	1261	Missense	distal	5	no	10.715	10.738	EPSD	TCGA;ICGC;COSMIC	7.780	Up-regulation
AGC_Akt_AKT1_ST	Q15672	TWIST1	P31749	AKT1	S42	A46T	46	Missense	distal	4	no	18.341	18.212	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	Q15672	TWIST1	P31749	AKT1	S45	A46T	46	Missense	proximal	1	no	8.967	9.234	EPSD	TCGA;ICGC;COSMIC	7.780	Up-regulation
AGC_Akt_AKT1_ST	Q15672	TWIST1	P31749	AKT1	T121	R118C	118	Missense	distal	-3	no	14.091	7.918	PhosphoSitePlus;EPSD	TCGA;ICGC;COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	Q15672	TWIST1	P31749	AKT1	T121	N114S	114	Missense	distal	-7	no	14.091	14.206	PhosphoSitePlus;EPSD	TCGA;ICGC;COSMIC	7.780	Up-regulation
AGC_Akt_AKT1_ST	Q15672	TWIST1	P31749	AKT1	T121	A127V	127	Missense	distal	6	no	14.091	14.060	PhosphoSitePlus;EPSD	TCGA;ICGC;COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	Q15672	TWIST1	P31749	AKT1	T121	R116W	116	Missense	distal	-5	no	14.091	8.571	PhosphoSitePlus;EPSD	TCGA;ICGC;COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	Q15672	TWIST1	P31749	AKT1	T121	E117Q	117	Missense	distal	-4	no	14.091	14.067	PhosphoSitePlus;EPSD	TCGA;ICGC;COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	Q15672	TWIST1	P31749	AKT1	S123	R118C	118	Missense	distal	-5	no	16.369	12.292	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	Q15672	TWIST1	P31749	AKT1	S123	A127V	127	Missense	distal	4	no	16.369	16.425	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	7.780	Up-regulation
AGC_Akt_AKT1_ST	Q15672	TWIST1	P31749	AKT1	S123	R116W	116	Missense	distal	-7	no	16.369	15.946	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	Q15672	TWIST1	P31749	AKT1	S123	E117Q	117	Missense	distal	-6	no	16.369	16.366	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	P00533	EGFR	P31749	AKT1	S227	R222C	222	Missense	distal	-5	no	14.385	10.308	EPSD	TCGA;COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	P00533	EGFR	P31749	AKT1	S227	S229C	229	Missense	proximal	2	no	14.385	13.560	EPSD	TCGA;COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	P00533	EGFR	P31749	AKT1	S227	C223Y	223	Missense	distal	-4	no	14.385	15.118	EPSD	TCGA;COSMIC	7.780	Up-regulation
AGC_Akt_AKT1_ST	P00533	EGFR	P31749	AKT1	S227	R222L	222	Missense	distal	-5	no	14.385	10.259	EPSD	TCGA;COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	P00533	EGFR	P31749	AKT1	S227	S227F	227	Missense	central	0	yes	14.385	0.000	EPSD	TCGA;COSMIC	7.780	Loss
AGC_Akt_AKT1_ST	P00533	EGFR	P31749	AKT1	S227	P228L	228	Missense	proximal	1	no	14.385	14.639	EPSD	TCGA;COSMIC	7.780	Up-regulation
AGC_Akt_AKT1_ST	P00533	EGFR	P31749	AKT1	S227	N234S	234	Missense	distal	7	no	14.385	14.420	EPSD	TCGA;COSMIC	7.780	Up-regulation
AGC_Akt_AKT1_ST	P00533	EGFR	P31749	AKT1	S227	R224H	224	Missense	distal	-3	no	14.385	9.686	EPSD	TCGA;COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	P00533	EGFR	P31749	AKT1	S229	R222C	222	Missense	distal	-7	no	10.795	10.316	PhosphoSitePlus	TCGA;COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	P00533	EGFR	P31749	AKT1	S229	S229C	229	Missense	central	0	yes	10.795	0.000	PhosphoSitePlus	TCGA;COSMIC	7.780	Loss
AGC_Akt_AKT1_ST	P00533	EGFR	P31749	AKT1	S229	C223Y	223	Missense	distal	-6	no	10.795	10.882	PhosphoSitePlus	TCGA;COSMIC	7.780	Up-regulation
AGC_Akt_AKT1_ST	P00533	EGFR	P31749	AKT1	S229	R222L	222	Missense	distal	-7	no	10.795	10.505	PhosphoSitePlus	TCGA;COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	P00533	EGFR	P31749	AKT1	S229	S227F	227	Missense	proximal	-2	no	10.795	9.928	PhosphoSitePlus	TCGA;COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	P00533	EGFR	P31749	AKT1	S229	N234S	234	Missense	distal	5	no	10.795	10.829	PhosphoSitePlus	TCGA;COSMIC	7.780	Up-regulation
AGC_Akt_AKT1_ST	P00533	EGFR	P31749	AKT1	S229	R224H	224	Missense	distal	-5	no	10.795	7.700	PhosphoSitePlus	TCGA;COSMIC	7.780	Loss
AGC_Akt_AKT1_ST	P00533	EGFR	P31749	AKT1	S645	V651M	651	Missense	distal	6	no	7.881	7.896	EPSD	TCGA;COSMIC	7.780	Up-regulation
AGC_Akt_AKT1_ST	P00533	EGFR	P31749	AKT1	S645	S645C	645	Missense	central	0	yes	7.881	0.000	EPSD	TCGA;COSMIC	7.780	Loss
AGC_Akt_AKT1_ST	P00533	EGFR	P31749	AKT1	S645	M650I	650	Missense	distal	5	no	7.881	7.841	EPSD	TCGA;COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	P00533	EGFR	P31749	AKT1	S645	T638M	638	Missense	distal	-7	no	7.881	7.615	EPSD	TCGA;COSMIC	7.780	Loss
AGC_Akt_AKT1_ST	P00533	EGFR	P31749	AKT1	T678	R675W	675	Missense	distal	-3	no	12.009	3.069	EPSD	TCGA	7.780	Loss
AGC_Akt_AKT1_ST	P00533	EGFR	P31749	AKT1	T678	R677H	677	Missense	proximal	-1	no	12.009	11.965	EPSD	TCGA;COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	P00533	EGFR	P31749	AKT1	T678	R681M	681	Missense	distal	3	no	12.009	11.941	EPSD	TCGA	7.780	Down-regulation
AGC_Akt_AKT1_ST	P00533	EGFR	P31749	AKT1	T678	Q684H	684	Missense	distal	6	no	12.009	11.961	EPSD	TCGA	7.780	Down-regulation
AGC_Akt_AKT1_ST	P00533	EGFR	P31749	AKT1	T678	T678M	678	Missense	central	0	yes	12.009	0.000	EPSD	TCGA;GDSC;CCLE	7.780	Loss
AGC_Akt_AKT1_ST	P00533	EGFR	P31749	AKT1	T892	H893Y	893	Missense	proximal	1	no	9.917	10.087	EPSD	TCGA;COSMIC	7.780	Up-regulation
AGC_Akt_AKT1_ST	P00533	EGFR	P31749	AKT1	T892	Y891C	891	Missense	proximal	-1	no	9.917	9.882	EPSD	TCGA;COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	P00533	EGFR	P31749	AKT1	S991	F997V	997	Missense	distal	6	no	10.653	10.659	EPSD	TCGA;COSMIC	7.780	Up-regulation
AGC_Akt_AKT1_ST	P00533	EGFR	P31749	AKT1	S1036	T1032S	1032	Missense	distal	-4	no	10.626	10.570	EPSD	TCGA;COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	P00533	EGFR	P31749	AKT1	S1036	S1042N	1042	Missense	distal	6	no	10.626	10.558	EPSD	TCGA;COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	P00533	EGFR	P31749	AKT1	S1036	R1031Q	1031	Missense	distal	-5	no	10.626	6.399	EPSD	TCGA;COSMIC	7.780	Loss
AGC_Akt_AKT1_ST	P00533	EGFR	P31749	AKT1	S1071	R1068Q	1068	Missense	distal	-3	no	10.987	3.776	EPSD	TCGA;COSMIC	7.780	Loss
AGC_Akt_AKT1_ST	P00533	EGFR	P31749	AKT1	S1190	G1185V	1185	Missense	distal	-5	no	7.988	7.738	EPSD	TCGA;ICGC;COSMIC	7.780	Loss
AGC_Akt_AKT1_ST	P00533	EGFR	P31749	AKT1	S1190	A1195T	1195	Missense	distal	5	no	7.988	8.039	EPSD	TCGA;ICGC	7.780	Up-regulation
AGC_Akt_AKT1_ST	P00533	EGFR	P31749	AKT1	S1204	A1201V	1201	Missense	distal	-3	no	11.475	10.913	EPSD	TCGA;ICGC;COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	Q8TDN4	CABLES1	P31749	AKT1	S257	A251V	251	Missense	distal	-6	no	12.099	12.078	EPSD	TCGA;ICGC;COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	Q8TDN4	CABLES1	P31749	AKT1	S287	R283W	283	Missense	distal	-4	no	16.255	14.706	EPSD	TCGA;COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	Q8TDN4	CABLES1	P31749	AKT1	S287	S290F	290	Missense	distal	3	no	16.255	16.157	EPSD	TCGA;COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	Q8TDN4	CABLES1	P31749	AKT1	S287	R283Q	283	Missense	distal	-4	no	16.255	15.634	EPSD	TCGA;COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	Q8TDN4	CABLES1	P31749	AKT1	T309	A302T	302	Missense	distal	-7	no	10.541	10.741	EPSD;PhosphoSitePlus	TCGA;COSMIC	7.780	Up-regulation
AGC_Akt_AKT1_ST	Q8TDN4	CABLES1	P31749	AKT1	T309	R305W	305	Missense	distal	-4	no	10.541	8.992	EPSD;PhosphoSitePlus	TCGA;COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	Q8TDN4	CABLES1	P31749	AKT1	S311	R305W	305	Missense	distal	-6	no	15.323	15.176	EPSD	TCGA;COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	Q8TDN4	CABLES1	P31749	AKT1	S311	K317N	317	Missense	distal	6	no	15.323	15.245	EPSD	TCGA;COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	Q8TDN4	CABLES1	P31749	AKT1	S313	K317N	317	Missense	distal	4	no	10.129	10.261	EPSD	TCGA;COSMIC	7.780	Up-regulation
AGC_Akt_AKT1_ST	Q8TDN4	CABLES1	P31749	AKT1	T374	S373P	373	Missense	proximal	-1	no	9.611	9.582	EPSD	TCGA;ICGC;COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	Q8TDN4	CABLES1	P31749	AKT1	T415	R413I	413	Missense	proximal	-2	no	9.748	8.695	PhosphoSitePlus;EPSD	TCGA;ICGC;COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	Q8TDN4	CABLES1	P31749	AKT1	T415	A408V	408	Missense	distal	-7	no	9.748	9.619	PhosphoSitePlus;EPSD	TCGA;ICGC;COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	Q8TDN4	CABLES1	P31749	AKT1	S418	R413I	413	Missense	distal	-5	no	8.321	3.754	EPSD	TCGA;ICGC;COSMIC	7.780	Loss
AGC_Akt_AKT1_ST	Q8TDN4	CABLES1	P31749	AKT1	S429	L428P	428	Missense	proximal	-1	no	11.263	11.262	EPSD	TCGA;ICGC;COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	Q8TDN4	CABLES1	P31749	AKT1	S429	G436D	436	Missense	distal	7	no	11.263	11.259	EPSD	TCGA;ICGC;COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	Q8TDN4	CABLES1	P31749	AKT1	S434	L428P	428	Missense	distal	-6	no	12.832	12.819	EPSD	TCGA;ICGC;COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	Q8TDN4	CABLES1	P31749	AKT1	S434	G436D	436	Missense	proximal	2	no	12.832	12.565	EPSD	TCGA;ICGC;COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	P38936	CDKN1A	P31749	AKT1	T97	R94W	94	Missense	distal	-3	no	11.891	2.951	EPSD	TCGA;ICGC;COSMIC	7.780	Loss
AGC_Akt_AKT1_ST	P38936	CDKN1A	P31749	AKT1	T97	R93S	93	Missense	distal	-4	no	11.891	11.806	EPSD	TCGA;ICGC;COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	P38936	CDKN1A	P31749	AKT1	T97	R94P	94	Missense	distal	-3	no	11.891	5.252	EPSD	TCGA;ICGC;COSMIC	7.780	Loss
AGC_Akt_AKT1_ST	P38936	CDKN1A	P31749	AKT1	T97	P95S	95	Missense	proximal	-2	no	11.891	12.716	EPSD	TCGA;ICGC;COSMIC	7.780	Up-regulation
AGC_Akt_AKT1_ST	P38936	CDKN1A	P31749	AKT1	S98	R94W	94	Missense	distal	-4	no	8.115	6.566	EPSD	TCGA;ICGC;COSMIC	7.780	Loss
AGC_Akt_AKT1_ST	P38936	CDKN1A	P31749	AKT1	S98	R93S	93	Missense	distal	-5	no	8.115	3.645	EPSD	TCGA;ICGC;COSMIC	7.780	Loss
AGC_Akt_AKT1_ST	P38936	CDKN1A	P31749	AKT1	S98	R94P	94	Missense	distal	-4	no	8.115	7.293	EPSD	TCGA;ICGC;COSMIC	7.780	Loss
AGC_Akt_AKT1_ST	P38936	CDKN1A	P31749	AKT1	S98	P95S	95	Missense	distal	-3	no	8.115	6.978	EPSD	TCGA;ICGC;COSMIC	7.780	Loss
AGC_Akt_AKT1_ST	P38936	CDKN1A	P31749	AKT1	T145	D149H	149	Missense	distal	4	no	17.056	17.027	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	P38936	CDKN1A	P31749	AKT1	T145	R142W	142	Missense	distal	-3	no	17.056	8.115	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC;GDSC;CCLE	7.780	Down-regulation
AGC_Akt_AKT1_ST	P38936	CDKN1A	P31749	AKT1	S146	S153C	153	Missense	distal	7	no	16.217	16.094	PhosphoSitePlus;EPSD	TCGA;ICGC;COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	P38936	CDKN1A	P31749	AKT1	S146	D149H	149	Missense	distal	3	no	16.217	16.228	PhosphoSitePlus;EPSD	TCGA;ICGC;COSMIC	7.780	Up-regulation
AGC_Akt_AKT1_ST	P38936	CDKN1A	P31749	AKT1	S146	R142W	142	Missense	distal	-4	no	16.217	14.668	PhosphoSitePlus;EPSD	TCGA;ICGC;COSMIC;GDSC;CCLE	7.780	Down-regulation
AGC_Akt_AKT1_ST	P38936	CDKN1A	P31749	AKT1	S153	S153C	153	Missense	central	0	yes	9.724	0.000	EPSD	TCGA;ICGC;COSMIC	7.780	Loss
AGC_Akt_AKT1_ST	P38936	CDKN1A	P31749	AKT1	S153	R155H	155	Missense	proximal	2	no	9.724	9.363	EPSD	TCGA;ICGC;COSMIC;CCLE	7.780	Down-regulation
AGC_Akt_AKT1_ST	P38936	CDKN1A	P31749	AKT1	S153	D149H	149	Missense	distal	-4	no	9.724	10.038	EPSD	TCGA;ICGC;COSMIC	7.780	Up-regulation
AGC_Akt_AKT1_ST	P38936	CDKN1A	P31749	AKT1	S160	S153C	153	Missense	distal	-7	no	10.380	9.957	EPSD	TCGA;ICGC;COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	P38936	CDKN1A	P31749	AKT1	S160	R155H	155	Missense	distal	-5	no	10.380	7.285	EPSD	TCGA;ICGC;COSMIC;CCLE	7.780	Loss
AGC_Akt_AKT1_ST	P38936	CDKN1A	P31749	AKT1	S160	R162S	162	Missense	proximal	2	no	10.380	10.552	EPSD	TCGA;ICGC;COSMIC	7.780	Up-regulation
AGC_Akt_AKT1_ST	O75030	MITF	P31749	AKT1	T23	H18R	18	Missense	distal	-5	no	5.304	8.399	EPSD	TCGA;ICGC	7.780	Gain
AGC_Akt_AKT1_ST	P51617	IRAK1	P31749	AKT1	S120	E126D	126	Missense	distal	6	no	11.741	11.651	EPSD	TCGA;COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	P51617	IRAK1	P31749	AKT1	S371	S373R	373	Missense	proximal	2	no	9.035	8.863	EPSD	TCGA;COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	P51617	IRAK1	P31749	AKT1	S371	S376R	376	Missense	distal	5	no	9.035	9.042	EPSD	TCGA	7.780	Up-regulation
AGC_Akt_AKT1_ST	P51617	IRAK1	P31749	AKT1	S376	S373R	373	Missense	distal	-3	no	2.454	10.231	EPSD	TCGA;COSMIC	7.780	Gain
AGC_Akt_AKT1_ST	P51617	IRAK1	P31749	AKT1	S556	A559T	559	Missense	distal	3	no	11.753	11.810	EPSD	TCGA;COSMIC	7.780	Up-regulation
AGC_Akt_AKT1_ST	O75376	NCOR1	P31749	AKT1	S24	P22L	22	Missense	proximal	-2	no	8.966	8.934	EPSD	TCGA;ICGC;COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	O75376	NCOR1	P31749	AKT1	S70	R66L	66	Missense	distal	-4	no	11.234	10.024	EPSD	TCGA;ICGC;COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	O75376	NCOR1	P31749	AKT1	S70	Q63H	63	Missense	distal	-7	no	11.234	11.127	EPSD	TCGA;ICGC;COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	O75376	NCOR1	P31749	AKT1	S70	R66Q	66	Missense	distal	-4	no	11.234	10.613	EPSD	TCGA;ICGC;COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	O75376	NCOR1	P31749	AKT1	S88	R86I	86	Missense	proximal	-2	no	11.655	10.603	EPSD	TCGA;ICGC;COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	O75376	NCOR1	P31749	AKT1	S88	E90K	90	Missense	proximal	2	no	11.655	11.860	EPSD	TCGA;ICGC;COSMIC	7.780	Up-regulation
AGC_Akt_AKT1_ST	O75376	NCOR1	P31749	AKT1	S88	P91S	91	Missense	distal	3	no	11.655	11.736	EPSD	TCGA;ICGC;COSMIC	7.780	Up-regulation
AGC_Akt_AKT1_ST	O75376	NCOR1	P31749	AKT1	S115	F119Y	119	Missense	distal	4	no	9.262	9.201	EPSD	TCGA;ICGC;COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	O75376	NCOR1	P31749	AKT1	S115	V114D	114	Missense	proximal	-1	no	9.262	9.249	EPSD	TCGA;ICGC;COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	O75376	NCOR1	P31749	AKT1	S224	E220K	220	Missense	distal	-4	no	7.573	8.157	EPSD	TCGA;ICGC;COSMIC	7.780	Gain
AGC_Akt_AKT1_ST	O75376	NCOR1	P31749	AKT1	S370	A367V	367	Missense	distal	-3	no	8.643	8.081	EPSD	TCGA;ICGC	7.780	Down-regulation
AGC_Akt_AKT1_ST	O75376	NCOR1	P31749	AKT1	S370	G363V	363	Missense	distal	-7	no	8.643	8.552	EPSD	TCGA;ICGC;COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	O75376	NCOR1	P31749	AKT1	S401	S401C	401	Missense	central	0	yes	11.034	0.000	EPSD	TCGA;ICGC;COSMIC	7.780	Loss
AGC_Akt_AKT1_ST	O75376	NCOR1	P31749	AKT1	S401	L400F	400	Missense	proximal	-1	no	11.034	11.028	EPSD	TCGA;ICGC;COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	O75376	NCOR1	P31749	AKT1	T586	R580C	580	Missense	distal	-6	no	9.066	8.886	EPSD	TCGA;ICGC;COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	O75376	NCOR1	P31749	AKT1	T586	R581C	581	Missense	distal	-5	no	9.066	4.990	EPSD	TCGA;ICGC;COSMIC	7.780	Loss
AGC_Akt_AKT1_ST	O75376	NCOR1	P31749	AKT1	T586	S588F	588	Missense	proximal	2	no	9.066	8.489	EPSD	TCGA;ICGC;COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	O75376	NCOR1	P31749	AKT1	T586	R584Q	584	Missense	proximal	-2	no	9.066	8.554	EPSD	TCGA;ICGC;COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	O75376	NCOR1	P31749	AKT1	T590	S588F	588	Missense	proximal	-2	no	12.112	11.245	EPSD	TCGA;ICGC;COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	O75376	NCOR1	P31749	AKT1	T590	R584Q	584	Missense	distal	-6	no	12.112	12.027	EPSD	TCGA;ICGC;COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	O75376	NCOR1	P31749	AKT1	S875	A868S	868	Missense	distal	-7	no	8.222	8.371	EPSD	TCGA;COSMIC	7.780	Up-regulation
AGC_Akt_AKT1_ST	O75376	NCOR1	P31749	AKT1	T991	C987Y	987	Missense	distal	-4	no	9.546	10.279	EPSD	TCGA;COSMIC	7.780	Up-regulation
AGC_Akt_AKT1_ST	O75376	NCOR1	P31749	AKT1	T991	S992R	992	Missense	proximal	1	no	9.546	9.690	EPSD	TCGA	7.780	Up-regulation
AGC_Akt_AKT1_ST	O75376	NCOR1	P31749	AKT1	S997	S992R	992	Missense	distal	-5	no	6.664	11.134	EPSD	TCGA	7.780	Gain
AGC_Akt_AKT1_ST	O75376	NCOR1	P31749	AKT1	S1151	G1147E	1147	Missense	distal	-4	no	8.316	8.533	EPSD	TCGA;COSMIC	7.780	Up-regulation
AGC_Akt_AKT1_ST	O75376	NCOR1	P31749	AKT1	S1151	S1154L	1154	Missense	distal	3	no	8.316	8.218	EPSD	TCGA;COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	O75376	NCOR1	P31749	AKT1	S1206	R1201K	1201	Missense	distal	-5	no	10.744	8.346	EPSD	TCGA;COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	O75376	NCOR1	P31749	AKT1	T1232	E1230K	1230	Missense	proximal	-2	no	10.472	11.132	EPSD	TCGA;COSMIC;GDSC;CCLE	7.780	Up-regulation
AGC_Akt_AKT1_ST	O75376	NCOR1	P31749	AKT1	T1232	I1225M	1225	Missense	distal	-7	no	10.472	10.629	EPSD	TCGA	7.780	Up-regulation
AGC_Akt_AKT1_ST	O75376	NCOR1	P31749	AKT1	T1232	G1231R	1231	Missense	proximal	-1	no	10.472	10.512	EPSD	TCGA;COSMIC	7.780	Up-regulation
AGC_Akt_AKT1_ST	O75376	NCOR1	P31749	AKT1	S1234	E1230K	1230	Missense	distal	-4	no	9.438	10.022	EPSD	TCGA;COSMIC;GDSC;CCLE	7.780	Up-regulation
AGC_Akt_AKT1_ST	O75376	NCOR1	P31749	AKT1	S1234	G1231R	1231	Missense	distal	-3	no	9.438	16.194	EPSD	TCGA;COSMIC	7.780	Up-regulation
AGC_Akt_AKT1_ST	O75376	NCOR1	P31749	AKT1	S1307	D1310H	1310	Missense	distal	3	no	9.458	9.469	EPSD	TCGA;COSMIC	7.780	Up-regulation
AGC_Akt_AKT1_ST	O75376	NCOR1	P31749	AKT1	S1307	E1309K	1309	Missense	proximal	2	no	9.458	9.663	EPSD	TCGA;COSMIC	7.780	Up-regulation
AGC_Akt_AKT1_ST	O75376	NCOR1	P31749	AKT1	S1307	L1312P	1312	Missense	distal	5	no	9.458	9.471	EPSD	TCGA;COSMIC	7.780	Up-regulation
AGC_Akt_AKT1_ST	O75376	NCOR1	P31749	AKT1	S1307	G1311D	1311	Missense	distal	4	no	9.458	9.509	EPSD	TCGA;COSMIC	7.780	Up-regulation
AGC_Akt_AKT1_ST	O75376	NCOR1	P31749	AKT1	T1361	P1355L	1355	Missense	distal	-6	no	8.177	8.191	EPSD	TCGA;COSMIC	7.780	Up-regulation
AGC_Akt_AKT1_ST	O75376	NCOR1	P31749	AKT1	T1361	Q1357R	1357	Missense	distal	-4	no	8.177	8.799	EPSD	TCGA;COSMIC	7.780	Up-regulation
AGC_Akt_AKT1_ST	O75376	NCOR1	P31749	AKT1	T1361	D1358H	1358	Missense	distal	-3	no	8.177	9.429	EPSD	TCGA;COSMIC	7.780	Up-regulation
AGC_Akt_AKT1_ST	O75376	NCOR1	P31749	AKT1	S1450	R1447Q	1447	Missense	distal	-3	no	15.706	8.495	PhosphoSitePlus	TCGA;COSMIC;GDSC;CCLE	7.780	Down-regulation
AGC_Akt_AKT1_ST	O75376	NCOR1	P31749	AKT1	S1450	S1446F	1446	Missense	distal	-4	no	15.706	14.538	PhosphoSitePlus	TCGA	7.780	Down-regulation
AGC_Akt_AKT1_ST	O75376	NCOR1	P31749	AKT1	S1450	R1445C	1445	Missense	distal	-5	no	15.706	11.629	PhosphoSitePlus	TCGA;COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	O75376	NCOR1	P31749	AKT1	S1487	P1485H	1485	Missense	proximal	-2	no	9.010	8.785	EPSD	TCGA;COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	O75376	NCOR1	P31749	AKT1	S1487	R1482W	1482	Missense	distal	-5	no	9.010	3.491	EPSD	TCGA;COSMIC	7.780	Loss
AGC_Akt_AKT1_ST	O75376	NCOR1	P31749	AKT1	S1487	V1486A	1486	Missense	proximal	-1	no	9.010	9.025	EPSD	TCGA;COSMIC	7.780	Up-regulation
AGC_Akt_AKT1_ST	O75376	NCOR1	P31749	AKT1	T1520	S1519L	1519	Missense	proximal	-1	no	12.586	12.557	EPSD	TCGA;COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	O75376	NCOR1	P31749	AKT1	T1520	H1515Y	1515	Missense	distal	-5	no	12.586	11.072	EPSD	TCGA;COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	O75376	NCOR1	P31749	AKT1	T1522	S1519L	1519	Missense	distal	-3	no	8.608	9.391	EPSD	TCGA;COSMIC	7.780	Up-regulation
AGC_Akt_AKT1_ST	O75376	NCOR1	P31749	AKT1	T1522	H1515Y	1515	Missense	distal	-7	no	8.608	8.647	EPSD	TCGA;COSMIC	7.780	Up-regulation
AGC_Akt_AKT1_ST	O75376	NCOR1	P31749	AKT1	T1555	R1561Q	1561	Missense	distal	6	no	10.415	10.344	EPSD	TCGA;COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	O75376	NCOR1	P31749	AKT1	T1555	A1556V	1556	Missense	proximal	1	no	10.415	10.487	EPSD	TCGA;COSMIC	7.780	Up-regulation
AGC_Akt_AKT1_ST	O75376	NCOR1	P31749	AKT1	T1555	G1557D	1557	Missense	proximal	2	no	10.415	10.148	EPSD	TCGA	7.780	Down-regulation
AGC_Akt_AKT1_ST	O75376	NCOR1	P31749	AKT1	T1555	S1554I	1554	Missense	proximal	-1	no	10.415	10.365	EPSD	TCGA;COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	O75376	NCOR1	P31749	AKT1	S1592	Q1588H	1588	Missense	distal	-4	no	11.967	11.529	EPSD	TCGA;COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	O75376	NCOR1	P31749	AKT1	S1636	E1639G	1639	Missense	distal	3	no	11.783	11.733	EPSD	TCGA;COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	O75376	NCOR1	P31749	AKT1	S1733	P1740L	1740	Missense	distal	7	no	7.840	7.832	EPSD	TCGA;COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	O75376	NCOR1	P31749	AKT1	S1733	S1733F	1733	Missense	central	0	yes	7.840	0.000	EPSD	TCGA;COSMIC	7.780	Loss
AGC_Akt_AKT1_ST	O75376	NCOR1	P31749	AKT1	S1733	A1731T	1731	Missense	proximal	-2	no	7.840	8.226	EPSD	TCGA	7.780	Up-regulation
AGC_Akt_AKT1_ST	O75376	NCOR1	P31749	AKT1	S1742	P1740L	1740	Missense	proximal	-2	no	9.780	9.747	EPSD	TCGA;COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	O75376	NCOR1	P31749	AKT1	S1750	R1755C	1755	Missense	distal	5	no	11.999	11.873	EPSD	TCGA;COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	O75376	NCOR1	P31749	AKT1	S1758	R1755C	1755	Missense	distal	-3	no	11.618	5.444	EPSD	TCGA;COSMIC	7.780	Loss
AGC_Akt_AKT1_ST	O75376	NCOR1	P31749	AKT1	S1760	R1755C	1755	Missense	distal	-5	no	9.917	5.840	EPSD	TCGA;COSMIC	7.780	Loss
AGC_Akt_AKT1_ST	O75376	NCOR1	P31749	AKT1	S1955	R1950C	1950	Missense	distal	-5	no	8.599	4.522	EPSD	TCGA;COSMIC	7.780	Loss
AGC_Akt_AKT1_ST	O75376	NCOR1	P31749	AKT1	T1968	S1970R	1970	Missense	proximal	2	no	9.539	9.367	EPSD	TCGA	7.780	Down-regulation
AGC_Akt_AKT1_ST	O75376	NCOR1	P31749	AKT1	S1970	S1970R	1970	Missense	central	0	yes	9.236	0.000	EPSD	TCGA	7.780	Loss
AGC_Akt_AKT1_ST	O75376	NCOR1	P31749	AKT1	S2023	H2016Y	2016	Missense	distal	-7	no	8.368	8.407	EPSD	TCGA;COSMIC	7.780	Up-regulation
AGC_Akt_AKT1_ST	O75376	NCOR1	P31749	AKT1	S2070	Q2071K	2071	Missense	proximal	1	no	8.269	8.487	EPSD	TCGA;COSMIC	7.780	Up-regulation
AGC_Akt_AKT1_ST	O75376	NCOR1	P31749	AKT1	S2070	S2069F	2069	Missense	proximal	-1	no	8.269	8.234	EPSD	TCGA;COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	O75376	NCOR1	P31749	AKT1	S2070	A2064T	2064	Missense	distal	-6	no	8.269	8.355	EPSD	TCGA;COSMIC	7.780	Up-regulation
AGC_Akt_AKT1_ST	O75376	NCOR1	P31749	AKT1	S2070	S2069T	2069	Missense	proximal	-1	no	8.269	8.275	EPSD	TCGA;COSMIC	7.780	Up-regulation
AGC_Akt_AKT1_ST	O75376	NCOR1	P31749	AKT1	T2097	S2098L	2098	Missense	proximal	1	no	10.708	10.806	EPSD	TCGA;COSMIC	7.780	Up-regulation
AGC_Akt_AKT1_ST	O75376	NCOR1	P31749	AKT1	T2097	V2093A	2093	Missense	distal	-4	no	10.708	11.080	EPSD	TCGA;COSMIC	7.780	Up-regulation
AGC_Akt_AKT1_ST	O75376	NCOR1	P31749	AKT1	T2097	R2100C	2100	Missense	distal	3	no	10.708	10.547	EPSD	TCGA;COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	O75376	NCOR1	P31749	AKT1	S2117	R2114T	2114	Missense	distal	-3	no	11.593	4.571	EPSD	TCGA;COSMIC	7.780	Loss
AGC_Akt_AKT1_ST	O75376	NCOR1	P31749	AKT1	S2144	P2149H	2149	Missense	distal	5	no	10.794	10.780	EPSD	TCGA;COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	O75376	NCOR1	P31749	AKT1	S2144	Y2147N	2147	Missense	distal	3	no	10.794	10.806	EPSD	TCGA;COSMIC	7.780	Up-regulation
AGC_Akt_AKT1_ST	O75376	NCOR1	P31749	AKT1	S2144	P2137T	2137	Missense	distal	-7	no	10.794	11.038	EPSD	TCGA	7.780	Up-regulation
AGC_Akt_AKT1_ST	O75376	NCOR1	P31749	AKT1	S2144	S2144L	2144	Missense	central	0	yes	10.794	0.000	EPSD	TCGA;COSMIC	7.780	Loss
AGC_Akt_AKT1_ST	O75376	NCOR1	P31749	AKT1	S2164	L2167I	2167	Missense	distal	3	no	7.860	7.826	EPSD	TCGA;COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	O75376	NCOR1	P31749	AKT1	S2184	G2186R	2186	Missense	proximal	2	no	9.265	9.425	EPSD	TCGA;COSMIC	7.780	Up-regulation
AGC_Akt_AKT1_ST	O75376	NCOR1	P31749	AKT1	S2184	R2183H	2183	Missense	proximal	-1	no	9.265	9.220	EPSD	TCGA;COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	O75376	NCOR1	P31749	AKT1	S2184	Y2190H	2190	Missense	distal	6	no	9.265	9.233	EPSD	TCGA	7.780	Down-regulation
AGC_Akt_AKT1_ST	O75376	NCOR1	P31749	AKT1	S2189	G2186R	2186	Missense	distal	-3	no	3.701	10.457	EPSD	TCGA;COSMIC	7.780	Gain
AGC_Akt_AKT1_ST	O75376	NCOR1	P31749	AKT1	S2219	M2226I	2226	Missense	distal	7	no	8.285	8.246	EPSD	TCGA;COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	O75376	NCOR1	P31749	AKT1	S2219	S2219C	2219	Missense	central	0	yes	8.285	0.000	EPSD	TCGA;COSMIC;GDSC;CCLE	7.780	Loss
AGC_Akt_AKT1_ST	O75376	NCOR1	P31749	AKT1	S2219	R2214C	2214	Missense	distal	-5	no	8.285	4.208	EPSD	TCGA;COSMIC	7.780	Loss
AGC_Akt_AKT1_ST	O75376	NCOR1	P31749	AKT1	S2253	S2249C	2249	Missense	distal	-4	no	11.398	9.805	EPSD	TCGA;COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	O75376	NCOR1	P31749	AKT1	S2253	N2260K	2260	Missense	distal	7	no	11.398	11.433	EPSD	TCGA;COSMIC	7.780	Up-regulation
AGC_Akt_AKT1_ST	O75376	NCOR1	P31749	AKT1	S2253	G2251C	2251	Missense	proximal	-2	no	11.398	10.440	EPSD	TCGA;COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	O75376	NCOR1	P31749	AKT1	S2253	F2254S	2254	Missense	proximal	1	no	11.398	11.380	EPSD	TCGA;COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	O75376	NCOR1	P31749	AKT1	S2328	N2331H	2331	Missense	distal	3	no	8.086	8.043	EPSD	TCGA;COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	O75376	NCOR1	P31749	AKT1	S2328	K2334T	2334	Missense	distal	6	no	8.086	8.097	EPSD	TCGA;COSMIC	7.780	Up-regulation
AGC_Akt_AKT1_ST	O75376	NCOR1	P31749	AKT1	S2328	S2335Y	2335	Missense	distal	7	no	8.086	8.044	EPSD	TCGA;COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	O75376	NCOR1	P31749	AKT1	S2352	T2347M	2347	Missense	distal	-5	no	11.251	10.458	EPSD	TCGA;COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	O75376	NCOR1	P31749	AKT1	S2377	E2372K	2372	Missense	distal	-5	no	9.488	11.185	EPSD	TCGA;COSMIC	7.780	Up-regulation
AGC_Akt_AKT1_ST	O75376	NCOR1	P31749	AKT1	S2394	P2397L	2397	Missense	distal	3	no	11.708	11.692	EPSD	TCGA;COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	O75376	NCOR1	P31749	AKT1	S2394	R2391Q	2391	Missense	distal	-3	no	11.708	4.497	EPSD	TCGA;COSMIC	7.780	Loss
AGC_Akt_AKT1_ST	O75376	NCOR1	P31749	AKT1	S2394	R2391G	2391	Missense	distal	-3	no	11.708	4.952	EPSD	TCGA;COSMIC	7.780	Loss
AGC_Akt_AKT1_ST	O75376	NCOR1	P31749	AKT1	S2394	T2389I	2389	Missense	distal	-5	no	11.708	10.870	EPSD	TCGA	7.780	Down-regulation
AGC_Akt_AKT1_ST	O75376	NCOR1	P31749	AKT1	S2394	P2398S	2398	Missense	distal	4	no	11.708	11.552	EPSD	TCGA;COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	O75376	NCOR1	P31749	AKT1	T2396	P2397L	2397	Missense	proximal	1	no	9.216	9.470	EPSD	TCGA;COSMIC	7.780	Up-regulation
AGC_Akt_AKT1_ST	O75376	NCOR1	P31749	AKT1	T2396	R2391Q	2391	Missense	distal	-5	no	9.216	4.988	EPSD	TCGA;COSMIC	7.780	Loss
AGC_Akt_AKT1_ST	O75376	NCOR1	P31749	AKT1	T2396	R2391G	2391	Missense	distal	-5	no	9.216	5.151	EPSD	TCGA;COSMIC	7.780	Loss
AGC_Akt_AKT1_ST	O75376	NCOR1	P31749	AKT1	T2396	T2389I	2389	Missense	distal	-7	no	9.216	8.793	EPSD	TCGA	7.780	Down-regulation
AGC_Akt_AKT1_ST	O75376	NCOR1	P31749	AKT1	T2396	P2398S	2398	Missense	proximal	2	no	9.216	9.552	EPSD	TCGA;COSMIC	7.780	Up-regulation
AGC_Akt_AKT1_ST	O75376	NCOR1	P31749	AKT1	S2429	S2429L	2429	Missense	central	0	yes	7.847	0.000	EPSD	TCGA;COSMIC	7.780	Loss
AGC_Akt_AKT1_ST	O75376	NCOR1	P31749	AKT1	S2429	P2424H	2424	Missense	distal	-5	no	7.847	8.762	EPSD	TCGA;COSMIC	7.780	Up-regulation
AGC_Akt_AKT1_ST	P12755	SKI	P31749	AKT1	T103	V104L	104	Missense	proximal	1	no	9.827	9.927	EPSD	TCGA;ICGC;COSMIC	7.780	Up-regulation
AGC_Akt_AKT1_ST	P12755	SKI	P31749	AKT1	T103	E108Q	108	Missense	distal	5	no	9.827	9.816	EPSD	TCGA;ICGC;COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	P12755	SKI	P31749	AKT1	S325	R323Q	323	Missense	proximal	-2	no	8.452	7.939	EPSD	TCGA;ICGC;COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	P12755	SKI	P31749	AKT1	S326	R323Q	323	Missense	distal	-3	no	10.792	3.581	EPSD	TCGA;ICGC;COSMIC	7.780	Loss
AGC_Akt_AKT1_ST	P12755	SKI	P31749	AKT1	S383	S383F	383	Missense	central	0	yes	10.698	0.000	EPSD	TCGA;ICGC;COSMIC	7.780	Loss
AGC_Akt_AKT1_ST	P12755	SKI	P31749	AKT1	S383	A385T	385	Missense	proximal	2	no	10.698	10.999	EPSD	TCGA;ICGC;COSMIC	7.780	Up-regulation
AGC_Akt_AKT1_ST	P12755	SKI	P31749	AKT1	T458	P462T	462	Missense	distal	4	no	16.405	16.244	PhosphoSitePlus	TCGA;ICGC;COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	P05106	ITGB3	P31749	AKT1	T441	S439F	439	Missense	proximal	-2	no	9.003	8.136	EPSD	TCGA;ICGC;COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	P05106	ITGB3	P31749	AKT1	S667	E664K	664	Missense	distal	-3	no	7.745	9.796	EPSD	TCGA;ICGC;COSMIC	7.780	Gain
AGC_Akt_AKT1_ST	P05106	ITGB3	P31749	AKT1	T767	Y773H	773	Missense	distal	6	no	9.579	9.546	EPSD	TCGA;ICGC;COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	P05106	ITGB3	P31749	AKT1	T767	N770S	770	Missense	distal	3	no	9.579	9.635	EPSD	TCGA;COSMIC	7.780	Up-regulation
AGC_Akt_AKT1_ST	P05106	ITGB3	P31749	AKT1	T767	A761T	761	Missense	distal	-6	no	9.579	9.664	EPSD	TCGA;ICGC;COSMIC	7.780	Up-regulation
AGC_Akt_AKT1_ST	P05106	ITGB3	P31749	AKT1	T767	T767K	767	Missense	central	0	yes	9.579	0.000	EPSD	TCGA;ICGC;COSMIC	7.780	Loss
AGC_Akt_AKT1_ST	P05106	ITGB3	P31749	AKT1	T767	R762K	762	Missense	distal	-5	no	9.579	7.181	EPSD	TCGA;ICGC;COSMIC	7.780	Loss
AGC_Akt_AKT1_ST	P05106	ITGB3	P31749	AKT1	T777	T784M	784	Missense	distal	7	no	9.005	8.936	EPSD	TCGA;ICGC;COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	P05106	ITGB3	P31749	AKT1	T777	Y773H	773	Missense	distal	-4	no	9.005	8.891	EPSD	TCGA;ICGC;COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	P05106	ITGB3	P31749	AKT1	T777	N770S	770	Missense	distal	-7	no	9.005	9.119	EPSD	TCGA;COSMIC	7.780	Up-regulation
AGC_Akt_AKT1_ST	P05106	ITGB3	P31749	AKT1	T777	S778C	778	Missense	proximal	1	no	9.005	8.621	EPSD	TCGA;ICGC;COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	P05106	ITGB3	P31749	AKT1	S778	T784M	784	Missense	distal	6	no	9.215	9.096	EPSD	TCGA;ICGC;COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	P05106	ITGB3	P31749	AKT1	S778	Y773H	773	Missense	distal	-5	no	9.215	10.728	EPSD	TCGA;ICGC;COSMIC	7.780	Up-regulation
AGC_Akt_AKT1_ST	P05106	ITGB3	P31749	AKT1	S778	S778C	778	Missense	central	0	yes	9.215	0.000	EPSD	TCGA;ICGC;COSMIC	7.780	Loss
AGC_Akt_AKT1_ST	P05106	ITGB3	P31749	AKT1	T779	T784M	784	Missense	distal	5	no	8.504	8.446	PhosphoSitePlus	TCGA;ICGC;COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	P05106	ITGB3	P31749	AKT1	T779	Y773H	773	Missense	distal	-6	no	8.504	8.478	PhosphoSitePlus	TCGA;ICGC;COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	P05106	ITGB3	P31749	AKT1	T779	R786Q	786	Missense	distal	7	no	8.504	8.448	PhosphoSitePlus	TCGA;ICGC;COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	P05106	ITGB3	P31749	AKT1	T779	S778C	778	Missense	proximal	-1	no	8.504	8.443	PhosphoSitePlus	TCGA;ICGC;COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	Q9BXL7	CARD11	P31749	AKT1	S116	E121Q	121	Missense	distal	5	no	12.134	12.123	EPSD	TCGA;ICGC;COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	Q9BXL7	CARD11	P31749	AKT1	S116	P111H	111	Missense	distal	-5	no	12.134	13.050	EPSD	TCGA;ICGC;COSMIC	7.780	Up-regulation
AGC_Akt_AKT1_ST	Q9BXL7	CARD11	P31749	AKT1	S116	R113W	113	Missense	distal	-3	no	12.134	3.194	EPSD	TCGA;ICGC;COSMIC	7.780	Loss
AGC_Akt_AKT1_ST	Q9BXL7	CARD11	P31749	AKT1	T117	E121Q	121	Missense	distal	4	no	10.169	10.224	EPSD	TCGA;ICGC;COSMIC	7.780	Up-regulation
AGC_Akt_AKT1_ST	Q9BXL7	CARD11	P31749	AKT1	T117	P111H	111	Missense	distal	-6	no	10.169	10.148	EPSD	TCGA;ICGC;COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	Q9BXL7	CARD11	P31749	AKT1	T117	H124R	124	Missense	distal	7	no	10.169	10.240	EPSD	TCGA;ICGC;COSMIC	7.780	Up-regulation
AGC_Akt_AKT1_ST	Q9BXL7	CARD11	P31749	AKT1	T117	R113W	113	Missense	distal	-4	no	10.169	8.620	EPSD	TCGA;ICGC;COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	Q9BXL7	CARD11	P31749	AKT1	S212	A209T	209	Missense	distal	-3	no	9.759	9.040	EPSD	TCGA;ICGC;COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	Q9BXL7	CARD11	P31749	AKT1	S212	K215N	215	Missense	distal	3	no	9.759	9.700	EPSD	TCGA;ICGC;COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	Q9BXL7	CARD11	P31749	AKT1	S212	R207C	207	Missense	distal	-5	no	9.759	5.682	EPSD	TCGA;ICGC;COSMIC	7.780	Loss
AGC_Akt_AKT1_ST	Q9BXL7	CARD11	P31749	AKT1	S212	K215T	215	Missense	distal	3	no	9.759	9.755	EPSD	TCGA;ICGC;COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	Q9BXL7	CARD11	P31749	AKT1	S439	S433R	433	Missense	distal	-6	no	12.607	12.641	EPSD	TCGA;ICGC;COSMIC	7.780	Up-regulation
AGC_Akt_AKT1_ST	Q9BXL7	CARD11	P31749	AKT1	S439	S433T	433	Missense	distal	-6	no	12.607	12.638	EPSD	TCGA;ICGC;COSMIC	7.780	Up-regulation
AGC_Akt_AKT1_ST	Q9BXL7	CARD11	P31749	AKT1	S512	R518Q	518	Missense	distal	6	no	11.042	10.971	EPSD	TCGA;ICGC;COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	Q9BXL7	CARD11	P31749	AKT1	T586	H583R	583	Missense	distal	-3	no	7.247	11.945	EPSD	TCGA;ICGC;COSMIC	7.780	Gain
AGC_Akt_AKT1_ST	Q9BXL7	CARD11	P31749	AKT1	S644	M639K	639	Missense	distal	-5	no	12.029	14.154	EPSD;PhosphoSitePlus	TCGA	7.780	Up-regulation
AGC_Akt_AKT1_ST	Q9BXL7	CARD11	P31749	AKT1	S644	F640L	640	Missense	distal	-4	no	12.029	12.073	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	7.780	Up-regulation
AGC_Akt_AKT1_ST	Q9BXL7	CARD11	P31749	AKT1	S644	S644Y	644	Missense	central	0	yes	12.029	0.000	EPSD;PhosphoSitePlus	TCGA;ICGC	7.780	Loss
AGC_Akt_AKT1_ST	Q9BXL7	CARD11	P31749	AKT1	S652	S652L	652	Missense	central	0	yes	10.482	0.000	PhosphoSitePlus;EPSD	TCGA;ICGC;COSMIC;GDSC;CCLE	7.780	Loss
AGC_Akt_AKT1_ST	Q9BXL7	CARD11	P31749	AKT1	S652	G657E	657	Missense	distal	5	no	10.482	10.512	PhosphoSitePlus;EPSD	TCGA;ICGC;COSMIC	7.780	Up-regulation
AGC_Akt_AKT1_ST	Q9BXL7	CARD11	P31749	AKT1	S655	S652L	652	Missense	distal	-3	no	7.875	8.657	EPSD	TCGA;ICGC;COSMIC;GDSC;CCLE	7.780	Up-regulation
AGC_Akt_AKT1_ST	Q9BXL7	CARD11	P31749	AKT1	S655	G657E	657	Missense	proximal	2	no	7.875	8.018	EPSD	TCGA;ICGC;COSMIC	7.780	Up-regulation
AGC_Akt_AKT1_ST	Q9BXL7	CARD11	P31749	AKT1	T871	A877V	877	Missense	distal	6	no	8.814	8.782	EPSD	TCGA;ICGC;COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	Q9BXL7	CARD11	P31749	AKT1	S923	R918W	918	Missense	distal	-5	no	14.521	9.001	EPSD	TCGA;ICGC;COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	Q9BXL7	CARD11	P31749	AKT1	S923	P926L	926	Missense	distal	3	no	14.521	14.504	EPSD	TCGA;ICGC;COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	Q9BXL7	CARD11	P31749	AKT1	S925	P926L	926	Missense	proximal	1	no	7.654	7.908	EPSD	TCGA;ICGC;COSMIC	7.780	Gain
AGC_Akt_AKT1_ST	Q9BXL7	CARD11	P31749	AKT1	T1020	R1027Q	1027	Missense	distal	7	no	11.802	11.746	EPSD	TCGA;ICGC;COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	Q9BXL7	CARD11	P31749	AKT1	T1020	Q1018R	1018	Missense	proximal	-2	no	11.802	12.314	EPSD	TCGA;ICGC;COSMIC	7.780	Up-regulation
AGC_Akt_AKT1_ST	Q9BXL7	CARD11	P31749	AKT1	T1020	T1020M	1020	Missense	central	0	yes	11.802	0.000	EPSD	TCGA;ICGC;COSMIC	7.780	Loss
AGC_Akt_AKT1_ST	P19544	WT1	P31749	AKT1	S428	Q422K	422	Missense	distal	-6	no	9.245	9.315	EPSD	TCGA;COSMIC	7.780	Up-regulation
AGC_Akt_AKT1_ST	P98177	FOXO4	P31749	AKT1	S30	P36L	36	Missense	distal	6	no	11.302	11.292	EPSD	TCGA;ICGC;COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	P98177	FOXO4	P31749	AKT1	T32	P36L	36	Missense	distal	4	no	15.576	15.608	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	7.780	Up-regulation
AGC_Akt_AKT1_ST	P98177	FOXO4	P31749	AKT1	S197	R192H	192	Missense	distal	-5	no	15.494	12.399	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	P98177	FOXO4	P31749	AKT1	S197	S202R	202	Missense	distal	5	no	15.494	15.502	EPSD;PhosphoSitePlus	TCGA;COSMIC	7.780	Up-regulation
AGC_Akt_AKT1_ST	P98177	FOXO4	P31749	AKT1	S197	R192C	192	Missense	distal	-5	no	15.494	11.417	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	P98177	FOXO4	P31749	AKT1	S217	E224K	224	Missense	distal	7	no	9.924	9.958	EPSD	TCGA;COSMIC	7.780	Up-regulation
AGC_Akt_AKT1_ST	P10276	RARA	P31749	AKT1	S369	V363L	363	Missense	distal	-6	no	16.466	16.491	EPSD	TCGA;COSMIC	7.780	Up-regulation
AGC_Akt_AKT1_ST	P10276	RARA	P31749	AKT1	S369	S369I	369	Missense	central	0	yes	16.466	0.000	EPSD	TCGA	7.780	Loss
AGC_Akt_AKT1_ST	Q96S44	TP53RK	P31749	AKT1	S250	R243C	243	Missense	distal	-7	no	17.625	17.146	PhosphoSitePlus	TCGA;GDSC	7.780	Down-regulation
AGC_Akt_AKT1_ST	P08727	KRT19	P31749	AKT1	S10	S9P	9	Missense	proximal	-1	no	13.670	13.641	EPSD	TCGA;ICGC;COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	P08727	KRT19	P31749	AKT1	S10	S3F	3	Missense	distal	-7	no	13.670	13.392	EPSD	TCGA;ICGC;COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	P08727	KRT19	P31749	AKT1	T12	S9P	9	Missense	distal	-3	no	10.134	11.271	EPSD	TCGA;ICGC;COSMIC	7.780	Up-regulation
AGC_Akt_AKT1_ST	P08727	KRT19	P31749	AKT1	S14	S9P	9	Missense	distal	-5	no	8.082	8.542	EPSD	TCGA;ICGC;COSMIC	7.780	Up-regulation
AGC_Akt_AKT1_ST	P08727	KRT19	P31749	AKT1	S46	A50S	50	Missense	distal	4	no	13.656	13.532	EPSD	TCGA;ICGC;COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	P08727	KRT19	P31749	AKT1	S48	A50S	50	Missense	proximal	2	no	11.675	12.051	EPSD	TCGA;ICGC;COSMIC	7.780	Up-regulation
AGC_Akt_AKT1_ST	P08727	KRT19	P31749	AKT1	S54	S57T	57	Missense	distal	3	no	10.731	10.730	EPSD	TCGA;ICGC;COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	P08727	KRT19	P31749	AKT1	S54	A60S	60	Missense	distal	6	no	10.731	10.813	EPSD	TCGA;ICGC;COSMIC	7.780	Up-regulation
AGC_Akt_AKT1_ST	P08727	KRT19	P31749	AKT1	S54	Y61C	61	Missense	distal	7	no	10.731	10.651	EPSD	TCGA;ICGC;COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	P08727	KRT19	P31749	AKT1	S54	A50S	50	Missense	distal	-4	no	10.731	11.453	EPSD	TCGA;ICGC;COSMIC	7.780	Up-regulation
AGC_Akt_AKT1_ST	P08727	KRT19	P31749	AKT1	S54	G59E	59	Missense	distal	5	no	10.731	10.762	EPSD	TCGA;ICGC	7.780	Up-regulation
AGC_Akt_AKT1_ST	P08727	KRT19	P31749	AKT1	S56	S57T	57	Missense	proximal	1	no	8.833	9.027	EPSD	TCGA;ICGC;COSMIC	7.780	Up-regulation
AGC_Akt_AKT1_ST	P08727	KRT19	P31749	AKT1	S56	A60S	60	Missense	distal	4	no	8.833	8.709	EPSD	TCGA;ICGC;COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	P08727	KRT19	P31749	AKT1	S56	Y61C	61	Missense	distal	5	no	8.833	8.758	EPSD	TCGA;ICGC;COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	P08727	KRT19	P31749	AKT1	S56	A50S	50	Missense	distal	-6	no	8.833	8.888	EPSD	TCGA;ICGC;COSMIC	7.780	Up-regulation
AGC_Akt_AKT1_ST	P08727	KRT19	P31749	AKT1	S56	G59E	59	Missense	distal	3	no	8.833	8.883	EPSD	TCGA;ICGC	7.780	Up-regulation
AGC_Akt_AKT1_ST	P08727	KRT19	P31749	AKT1	S93	L95M	95	Missense	proximal	2	no	9.315	9.444	EPSD	TCGA	7.780	Up-regulation
AGC_Akt_AKT1_ST	P08727	KRT19	P31749	AKT1	S93	D89V	89	Missense	distal	-4	no	9.315	9.509	EPSD	TCGA;ICGC;COSMIC	7.780	Up-regulation
AGC_Akt_AKT1_ST	P08727	KRT19	P31749	AKT1	T171	R166Q	166	Missense	distal	-5	no	9.225	4.998	EPSD	TCGA;ICGC;COSMIC	7.780	Loss
AGC_Akt_AKT1_ST	P08727	KRT19	P31749	AKT1	T171	R176H	176	Missense	distal	5	no	9.225	9.152	EPSD	TCGA;ICGC;COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	P08727	KRT19	P31749	AKT1	T171	T171M	171	Missense	central	0	yes	9.225	0.000	EPSD	TCGA;ICGC;COSMIC	7.780	Loss
AGC_Akt_AKT1_ST	P63104	YWHAZ	P31749	AKT1	T88	R83I	83	Missense	distal	-5	no	9.570	5.002	EPSD	TCGA;ICGC;COSMIC	7.780	Loss
AGC_Akt_AKT1_ST	P63104	YWHAZ	P31749	AKT1	T88	C94S	94	Missense	distal	6	no	9.570	9.773	EPSD	TCGA;ICGC;COSMIC	7.780	Up-regulation
AGC_Akt_AKT1_ST	Q9Y3M2	CBY1	P31749	AKT1	S20	P15S	15	Missense	distal	-5	no	10.579	10.119	PhosphoSitePlus	TCGA;ICGC;COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	Q9Y3M2	CBY1	P31749	AKT1	S20	S26A	26	Missense	distal	6	no	10.579	10.497	PhosphoSitePlus	TCGA;ICGC	7.780	Down-regulation
AGC_Akt_AKT1_ST	Q9Y3M2	CBY1	P31749	AKT1	S20	S26F	26	Missense	distal	6	no	10.579	10.460	PhosphoSitePlus	TCGA;ICGC;COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	Q9Y3M2	CBY1	P31749	AKT1	S22	P15S	15	Missense	distal	-7	no	8.719	8.913	EPSD	TCGA;ICGC;COSMIC	7.780	Up-regulation
AGC_Akt_AKT1_ST	Q9Y3M2	CBY1	P31749	AKT1	S22	S26A	26	Missense	distal	4	no	8.719	8.843	EPSD	TCGA;ICGC	7.780	Up-regulation
AGC_Akt_AKT1_ST	Q9Y3M2	CBY1	P31749	AKT1	S22	S26F	26	Missense	distal	4	no	8.719	8.915	EPSD	TCGA;ICGC;COSMIC	7.780	Up-regulation
AGC_Akt_AKT1_ST	Q9Y3M2	CBY1	P31749	AKT1	S22	D28V	28	Missense	distal	6	no	8.719	8.755	EPSD	TCGA;ICGC;COSMIC	7.780	Up-regulation
AGC_Akt_AKT1_ST	Q9Y3M2	CBY1	P31749	AKT1	S22	R29Q	29	Missense	distal	7	no	8.719	8.663	EPSD	TCGA;ICGC;COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	P98170	XIAP	P31749	AKT1	S9	S9Y	9	Missense	central	0	yes	8.912	0.000	EPSD	TCGA;ICGC;COSMIC	7.780	Loss
AGC_Akt_AKT1_ST	P98170	XIAP	P31749	AKT1	S9	K10N	10	Missense	proximal	1	no	8.912	8.756	EPSD	TCGA;ICGC	7.780	Down-regulation
AGC_Akt_AKT1_ST	P98170	XIAP	P31749	AKT1	T32	R29T	29	Missense	distal	-3	no	10.213	3.192	EPSD	TCGA;ICGC;COSMIC	7.780	Loss
AGC_Akt_AKT1_ST	P98170	XIAP	P31749	AKT1	T32	A34S	34	Missense	proximal	2	no	10.213	10.589	EPSD	TCGA;ICGC;COSMIC	7.780	Up-regulation
AGC_Akt_AKT1_ST	P98170	XIAP	P31749	AKT1	T32	E26G	26	Missense	distal	-6	no	10.213	10.180	EPSD	TCGA;ICGC;COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	P98170	XIAP	P31749	AKT1	T32	F33L	33	Missense	proximal	1	no	10.213	10.294	EPSD	TCGA;ICGC;COSMIC	7.780	Up-regulation
AGC_Akt_AKT1_ST	P98170	XIAP	P31749	AKT1	T32	R29I	29	Missense	distal	-3	no	10.213	3.132	EPSD	TCGA;ICGC;COSMIC	7.780	Loss
AGC_Akt_AKT1_ST	P98170	XIAP	P31749	AKT1	T32	T32N	32	Missense	central	0	yes	10.213	0.000	EPSD	TCGA	7.780	Loss
AGC_Akt_AKT1_ST	P98170	XIAP	P31749	AKT1	S87	R84S	84	Missense	distal	-3	no	15.077	7.301	PhosphoSitePlus	TCGA;ICGC;COSMIC	7.780	Loss
AGC_Akt_AKT1_ST	P98170	XIAP	P31749	AKT1	S87	H83Q	83	Missense	distal	-4	no	15.077	15.515	PhosphoSitePlus	TCGA;ICGC;COSMIC	7.780	Up-regulation
AGC_Akt_AKT1_ST	P98170	XIAP	P31749	AKT1	S261	M262I	262	Missense	proximal	1	no	12.601	12.416	EPSD	TCGA;ICGC;COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	P98170	XIAP	P31749	AKT1	S261	R258I	258	Missense	distal	-3	no	12.601	5.520	EPSD	TCGA;ICGC;COSMIC	7.780	Loss
AGC_Akt_AKT1_ST	P98170	XIAP	P31749	AKT1	S261	L256I	256	Missense	distal	-5	no	12.601	12.160	EPSD	TCGA;ICGC;COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	P98170	XIAP	P31749	AKT1	T359	R365I	365	Missense	distal	6	no	8.121	7.958	EPSD	TCGA;ICGC;CCLE	7.780	Down-regulation
AGC_Akt_AKT1_ST	P98170	XIAP	P31749	AKT1	T359	E357K	357	Missense	proximal	-2	no	8.121	8.780	EPSD	TCGA;ICGC;COSMIC	7.780	Up-regulation
AGC_Akt_AKT1_ST	P98170	XIAP	P31749	AKT1	T359	L362P	362	Missense	distal	3	no	8.121	8.137	EPSD	TCGA;ICGC;COSMIC	7.780	Up-regulation
AGC_Akt_AKT1_ST	P98170	XIAP	P31749	AKT1	S361	R365I	365	Missense	distal	4	no	8.845	9.095	EPSD	TCGA;ICGC;CCLE	7.780	Up-regulation
AGC_Akt_AKT1_ST	P98170	XIAP	P31749	AKT1	S361	E357K	357	Missense	distal	-4	no	8.845	9.429	EPSD	TCGA;ICGC;COSMIC	7.780	Up-regulation
AGC_Akt_AKT1_ST	P98170	XIAP	P31749	AKT1	S361	L362P	362	Missense	proximal	1	no	8.845	8.591	EPSD	TCGA;ICGC;COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	P98170	XIAP	P31749	AKT1	T363	R365I	365	Missense	proximal	2	no	8.331	7.846	EPSD	TCGA;ICGC;CCLE	7.780	Down-regulation
AGC_Akt_AKT1_ST	P98170	XIAP	P31749	AKT1	T363	E357K	357	Missense	distal	-6	no	8.331	8.397	EPSD	TCGA;ICGC;COSMIC	7.780	Up-regulation
AGC_Akt_AKT1_ST	P98170	XIAP	P31749	AKT1	T363	L362P	362	Missense	proximal	-1	no	8.331	8.330	EPSD	TCGA;ICGC;COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	P98170	XIAP	P31749	AKT1	S436	R443H	443	Missense	distal	7	no	9.045	8.974	EPSD	TCGA;ICGC;COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	P98170	XIAP	P31749	AKT1	S436	R443C	443	Missense	distal	7	no	9.045	8.915	EPSD	TCGA;ICGC;COSMIC;GDSC;CCLE	7.780	Down-regulation
AGC_Akt_AKT1_ST	P98170	XIAP	P31749	AKT1	S436	R443G	443	Missense	distal	7	no	9.045	8.964	EPSD	TCGA;ICGC;COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	P08047	SP1	P31749	AKT1	S42	T49A	49	Missense	distal	7	no	11.770	11.709	EPSD;PhosphoSitePlus	TCGA;ICGC	7.780	Down-regulation
AGC_Akt_AKT1_ST	P08047	SP1	P31749	AKT1	S73	S69N	69	Missense	distal	-4	no	11.657	11.090	EPSD	TCGA;ICGC;COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	P08047	SP1	P31749	AKT1	S73	C68R	68	Missense	distal	-5	no	11.657	15.734	EPSD	TCGA;ICGC;COSMIC	7.780	Up-regulation
AGC_Akt_AKT1_ST	P08047	SP1	P31749	AKT1	S73	P74S	74	Missense	proximal	1	no	11.657	11.812	EPSD	TCGA;ICGC;COSMIC	7.780	Up-regulation
AGC_Akt_AKT1_ST	P08047	SP1	P31749	AKT1	S73	S78N	78	Missense	distal	5	no	11.657	11.622	EPSD	TCGA;ICGC;COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	P08047	SP1	P31749	AKT1	S670	R666H	666	Missense	distal	-4	no	9.797	8.738	EPSD	TCGA;ICGC;COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	P08047	SP1	P31749	AKT1	S670	S670L	670	Missense	central	0	yes	9.797	0.000	EPSD	TCGA;ICGC;COSMIC	7.780	Loss
AGC_Akt_AKT1_ST	P08047	SP1	P31749	AKT1	S670	D671N	671	Missense	proximal	1	no	9.797	9.922	EPSD	TCGA;ICGC;COSMIC	7.780	Up-regulation
AGC_Akt_AKT1_ST	P08047	SP1	P31749	AKT1	S670	H676L	676	Missense	distal	6	no	9.797	9.814	EPSD	TCGA;ICGC;COSMIC	7.780	Up-regulation
AGC_Akt_AKT1_ST	P08047	SP1	P31749	AKT1	S670	R669C	669	Missense	proximal	-1	no	9.797	9.727	EPSD	TCGA;ICGC;COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	P08047	SP1	P31749	AKT1	T681	H676L	676	Missense	distal	-5	no	11.855	10.824	EPSD	TCGA;ICGC;COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	P08047	SP1	P31749	AKT1	S698	R697K	697	Missense	proximal	-1	no	7.812	7.808	PhosphoSitePlus;EPSD	TCGA;ICGC;COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	P08047	SP1	P31749	AKT1	S702	R697K	697	Missense	distal	-5	no	9.716	7.318	EPSD	TCGA;ICGC;COSMIC	7.780	Loss
AGC_Akt_AKT1_ST	P49841	GSK3B	P31749	AKT1	S13	Q19R	19	Missense	distal	6	no	7.992	8.063	EPSD	TCGA	7.780	Up-regulation
AGC_Akt_AKT1_ST	P49841	GSK3B	P31749	AKT1	S35	G34S	34	Missense	proximal	-1	no	10.668	10.698	EPSD	TCGA;COSMIC	7.780	Up-regulation
AGC_Akt_AKT1_ST	P49841	GSK3B	P31749	AKT1	S55	T59I	59	Missense	distal	4	no	8.668	8.935	EPSD	TCGA;ICGC;COSMIC	7.780	Up-regulation
AGC_Akt_AKT1_ST	P49841	GSK3B	P31749	AKT1	S55	D49N	49	Missense	distal	-6	no	8.668	8.740	EPSD	TCGA;ICGC;COSMIC	7.780	Up-regulation
AGC_Akt_AKT1_ST	P49841	GSK3B	P31749	AKT1	S147	R148G	148	Missense	proximal	1	no	10.133	9.683	EPSD	TCGA;ICGC;COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	Q53EL6	PDCD4	P31749	AKT1	S67	S67L	67	Missense	central	0	yes	15.873	0.000	PhosphoSitePlus;EPSD	TCGA;ICGC;COSMIC	7.780	Loss
AGC_Akt_AKT1_ST	Q53EL6	PDCD4	P31749	AKT1	S67	K65T	65	Missense	proximal	-2	no	15.873	15.556	PhosphoSitePlus;EPSD	TCGA;ICGC	7.780	Down-regulation
AGC_Akt_AKT1_ST	Q53EL6	PDCD4	P31749	AKT1	S67	R69Q	69	Missense	proximal	2	no	15.873	15.755	PhosphoSitePlus;EPSD	TCGA;ICGC;COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	Q53EL6	PDCD4	P31749	AKT1	S68	S67L	67	Missense	proximal	-1	no	8.819	8.790	EPSD	TCGA;ICGC;COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	Q53EL6	PDCD4	P31749	AKT1	S68	K65T	65	Missense	distal	-3	no	8.819	6.318	EPSD	TCGA;ICGC	7.780	Loss
AGC_Akt_AKT1_ST	Q53EL6	PDCD4	P31749	AKT1	S68	R69Q	69	Missense	proximal	1	no	8.819	8.524	EPSD	TCGA;ICGC;COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	Q53EL6	PDCD4	P31749	AKT1	S76	R69Q	69	Missense	distal	-7	no	11.265	11.071	EPSD	TCGA;ICGC;COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	Q53EL6	PDCD4	P31749	AKT1	S78	A84T	84	Missense	distal	6	no	8.800	8.903	EPSD	TCGA;ICGC;COSMIC	7.780	Up-regulation
AGC_Akt_AKT1_ST	Q53EL6	PDCD4	P31749	AKT1	S78	A84S	84	Missense	distal	6	no	8.800	8.882	EPSD	TCGA;ICGC;COSMIC	7.780	Up-regulation
AGC_Akt_AKT1_ST	Q53EL6	PDCD4	P31749	AKT1	S313	G308A	308	Missense	distal	-5	no	13.372	13.582	EPSD	TCGA;ICGC;COSMIC	7.780	Up-regulation
AGC_Akt_AKT1_ST	Q53EL6	PDCD4	P31749	AKT1	S313	R310H	310	Missense	distal	-3	no	13.372	8.674	EPSD	TCGA;ICGC;COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	Q53EL6	PDCD4	P31749	AKT1	S457	R463C	463	Missense	distal	6	no	19.966	19.765	EPSD;PhosphoSitePlus	TCGA	7.780	Down-regulation
AGC_Akt_AKT1_ST	Q53EL6	PDCD4	P31749	AKT1	S457	E458Q	458	Missense	proximal	1	no	19.966	19.912	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	Q53EL6	PDCD4	P31749	AKT1	S457	R454L	454	Missense	distal	-3	no	19.966	12.972	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	Q53EL6	PDCD4	P31749	AKT1	S457	E458K	458	Missense	proximal	1	no	19.966	20.130	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	7.780	Up-regulation
AGC_Akt_AKT1_ST	Q53EL6	PDCD4	P31749	AKT1	S468	R463C	463	Missense	distal	-5	no	11.491	7.414	EPSD	TCGA	7.780	Loss
AGC_Akt_AKT1_ST	P61247	RPS3A	P31749	AKT1	T10	A17D	17	Missense	distal	7	no	10.266	10.240	EPSD;PhosphoSitePlus	TCGA;ICGC	7.780	Down-regulation
AGC_Akt_AKT1_ST	P61247	RPS3A	P31749	AKT1	S112	K116T	116	Missense	distal	4	no	8.961	8.979	PhosphoSitePlus;EPSD	TCGA	7.780	Up-regulation
AGC_Akt_AKT1_ST	P61247	RPS3A	P31749	AKT1	S112	D108V	108	Missense	distal	-4	no	8.961	9.155	PhosphoSitePlus;EPSD	TCGA;ICGC;COSMIC	7.780	Up-regulation
AGC_Akt_AKT1_ST	Q9H6Z4	RANBP3	P31749	AKT1	S100	G94E	94	Missense	distal	-6	no	10.647	10.680	EPSD	TCGA;ICGC;COSMIC	7.780	Up-regulation
AGC_Akt_AKT1_ST	Q9H6Z4	RANBP3	P31749	AKT1	S100	G99C	99	Missense	proximal	-1	no	10.647	10.616	EPSD	TCGA	7.780	Down-regulation
AGC_Akt_AKT1_ST	Q9H6Z4	RANBP3	P31749	AKT1	S100	P102L	102	Missense	proximal	2	no	10.647	10.438	EPSD	TCGA;COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	Q9H6Z4	RANBP3	P31749	AKT1	S100	G99S	99	Missense	proximal	-1	no	10.647	10.677	EPSD	TCGA;COSMIC	7.780	Up-regulation
AGC_Akt_AKT1_ST	Q9H6Z4	RANBP3	P31749	AKT1	T124	E122G	122	Missense	proximal	-2	no	10.503	10.217	EPSD	TCGA;COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	Q9H6Z4	RANBP3	P31749	AKT1	T124	P117L	117	Missense	distal	-7	no	10.503	10.463	EPSD	TCGA;COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	Q9H6Z4	RANBP3	P31749	AKT1	T124	P131S	131	Missense	distal	7	no	10.503	10.561	EPSD	TCGA;COSMIC	7.780	Up-regulation
AGC_Akt_AKT1_ST	Q9H6Z4	RANBP3	P31749	AKT1	S125	E122G	122	Missense	distal	-3	no	8.185	8.001	EPSD	TCGA;COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	Q9H6Z4	RANBP3	P31749	AKT1	S125	P131S	131	Missense	distal	6	no	8.185	8.279	EPSD	TCGA;COSMIC	7.780	Up-regulation
AGC_Akt_AKT1_ST	Q9H6Z4	RANBP3	P31749	AKT1	S126	E122G	122	Missense	distal	-4	no	17.477	17.260	PhosphoSitePlus	TCGA;COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	Q9H6Z4	RANBP3	P31749	AKT1	S126	P131S	131	Missense	distal	5	no	17.477	17.530	PhosphoSitePlus	TCGA;COSMIC	7.780	Up-regulation
AGC_Akt_AKT1_ST	Q9H6Z4	RANBP3	P31749	AKT1	T128	E122G	122	Missense	distal	-6	no	9.509	9.475	EPSD	TCGA;COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	Q9H6Z4	RANBP3	P31749	AKT1	T128	P131S	131	Missense	distal	3	no	9.509	9.590	EPSD	TCGA;COSMIC	7.780	Up-regulation
AGC_Akt_AKT1_ST	Q9H6Z4	RANBP3	P31749	AKT1	S221	D225E	225	Missense	distal	4	no	11.061	10.914	EPSD	TCGA;COSMIC;GDSC;CCLE	7.780	Down-regulation
AGC_Akt_AKT1_ST	Q9H6Z4	RANBP3	P31749	AKT1	S333	E339K	339	Missense	distal	6	no	11.137	11.207	EPSD	TCGA;COSMIC	7.780	Up-regulation
AGC_Akt_AKT1_ST	Q9BVI0	PHF20	P31749	AKT1	S157	P160S	160	Missense	distal	3	no	8.595	8.676	EPSD	TCGA;ICGC;COSMIC	7.780	Up-regulation
AGC_Akt_AKT1_ST	Q9BVI0	PHF20	P31749	AKT1	S157	D161E	161	Missense	distal	4	no	8.595	8.449	EPSD	TCGA;CCLE	7.780	Down-regulation
AGC_Akt_AKT1_ST	Q9BVI0	PHF20	P31749	AKT1	S157	S155I	155	Missense	proximal	-2	no	8.595	7.354	EPSD	TCGA;ICGC	7.780	Loss
AGC_Akt_AKT1_ST	Q9BVI0	PHF20	P31749	AKT1	S232	E230A	230	Missense	proximal	-2	no	9.424	9.381	EPSD	TCGA;ICGC;COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	Q9BVI0	PHF20	P31749	AKT1	S265	R262I	262	Missense	distal	-3	no	15.666	8.585	PhosphoSitePlus;EPSD	TCGA	7.780	Down-regulation
AGC_Akt_AKT1_ST	Q9BVI0	PHF20	P31749	AKT1	S265	R262K	262	Missense	distal	-3	no	15.666	11.145	PhosphoSitePlus;EPSD	TCGA;ICGC;COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	Q9BVI0	PHF20	P31749	AKT1	S265	P263T	263	Missense	proximal	-2	no	15.666	16.424	PhosphoSitePlus;EPSD	TCGA;COSMIC	7.780	Up-regulation
AGC_Akt_AKT1_ST	Q9BVI0	PHF20	P31749	AKT1	S291	E295V	295	Missense	distal	4	no	15.793	15.895	EPSD;PhosphoSitePlus	TCGA	7.780	Up-regulation
AGC_Akt_AKT1_ST	Q9BVI0	PHF20	P31749	AKT1	S328	S324W	324	Missense	distal	-4	no	12.591	11.127	EPSD	TCGA;ICGC;COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	Q9BVI0	PHF20	P31749	AKT1	S328	R327H	327	Missense	proximal	-1	no	12.591	12.546	EPSD	TCGA;ICGC	7.780	Down-regulation
AGC_Akt_AKT1_ST	Q9BVI0	PHF20	P31749	AKT1	S329	S324W	324	Missense	distal	-5	no	10.877	9.827	EPSD	TCGA;ICGC;COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	Q9BVI0	PHF20	P31749	AKT1	S329	R327H	327	Missense	proximal	-2	no	10.877	10.016	EPSD	TCGA;ICGC	7.780	Down-regulation
AGC_Akt_AKT1_ST	Q9BVI0	PHF20	P31749	AKT1	S332	H337Y	337	Missense	distal	5	no	9.521	9.544	EPSD	TCGA;ICGC;COSMIC	7.780	Up-regulation
AGC_Akt_AKT1_ST	Q9BVI0	PHF20	P31749	AKT1	S332	E338D	338	Missense	distal	6	no	9.521	9.431	EPSD	TCGA;ICGC	7.780	Down-regulation
AGC_Akt_AKT1_ST	Q9BVI0	PHF20	P31749	AKT1	S332	R327H	327	Missense	distal	-5	no	9.521	6.426	EPSD	TCGA;ICGC	7.780	Loss
AGC_Akt_AKT1_ST	Q9BVI0	PHF20	P31749	AKT1	T333	H337Y	337	Missense	distal	4	no	10.213	10.153	EPSD	TCGA;ICGC;COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	Q9BVI0	PHF20	P31749	AKT1	T333	E338D	338	Missense	distal	5	no	10.213	10.170	EPSD	TCGA;ICGC	7.780	Down-regulation
AGC_Akt_AKT1_ST	Q9BVI0	PHF20	P31749	AKT1	T333	R327H	327	Missense	distal	-6	no	10.213	10.094	EPSD	TCGA;ICGC	7.780	Down-regulation
AGC_Akt_AKT1_ST	Q9BVI0	PHF20	P31749	AKT1	S500	G498D	498	Missense	proximal	-2	no	10.263	9.564	EPSD	TCGA;ICGC;COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	Q9BVI0	PHF20	P31749	AKT1	S502	E508K	508	Missense	distal	6	no	8.563	8.633	EPSD	TCGA;ICGC;COSMIC	7.780	Up-regulation
AGC_Akt_AKT1_ST	Q9BVI0	PHF20	P31749	AKT1	S502	G498D	498	Missense	distal	-4	no	8.563	8.005	EPSD	TCGA;ICGC;COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	P35226	BMI1	P31749	AKT1	S260	D256N	256	Missense	distal	-4	no	7.217	7.938	EPSD	TCGA;ICGC;COSMIC	7.780	Gain
AGC_Akt_AKT1_ST	Q15910	EZH2	P31749	AKT1	S8	K6M	6	Missense	proximal	-2	no	8.046	6.955	EPSD	TCGA;ICGC;COSMIC	7.780	Loss
AGC_Akt_AKT1_ST	Q15910	EZH2	P31749	AKT1	S8	T4I	4	Missense	distal	-4	no	8.046	6.608	EPSD	TCGA;ICGC;COSMIC	7.780	Loss
AGC_Akt_AKT1_ST	Q15910	EZH2	P31749	AKT1	S8	T4P	4	Missense	distal	-4	no	8.046	7.254	EPSD	TCGA;ICGC;COSMIC	7.780	Loss
AGC_Akt_AKT1_ST	Q15910	EZH2	P31749	AKT1	S21	R18C	18	Missense	distal	-3	no	15.763	9.589	PhosphoSitePlus	TCGA;ICGC;COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	Q15910	EZH2	P31749	AKT1	S21	Q28H	28	Missense	distal	7	no	15.763	15.747	PhosphoSitePlus	TCGA;ICGC	7.780	Down-regulation
AGC_Akt_AKT1_ST	Q15910	EZH2	P31749	AKT1	S21	R25Q	25	Missense	distal	4	no	15.763	15.886	PhosphoSitePlus	TCGA;ICGC;COSMIC	7.780	Up-regulation
AGC_Akt_AKT1_ST	Q15910	EZH2	P31749	AKT1	S212	R216Q	216	Missense	distal	4	no	10.215	10.339	EPSD	TCGA;COSMIC	7.780	Up-regulation
AGC_Akt_AKT1_ST	Q15910	EZH2	P31749	AKT1	S212	D208Y	208	Missense	distal	-4	no	10.215	10.644	EPSD	TCGA	7.780	Up-regulation
AGC_Akt_AKT1_ST	Q15910	EZH2	P31749	AKT1	S212	R207Q	207	Missense	distal	-5	no	10.215	5.988	EPSD	TCGA;ICGC;COSMIC	7.780	Loss
AGC_Akt_AKT1_ST	Q15910	EZH2	P31749	AKT1	S277	S271Y	271	Missense	distal	-6	no	12.745	12.687	EPSD	TCGA;COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	Q15910	EZH2	P31749	AKT1	S406	K400T	400	Missense	distal	-6	no	8.358	8.369	EPSD	TCGA;COSMIC	7.780	Up-regulation
AGC_Akt_AKT1_ST	Q96BF3	TMIGD2	P31749	AKT1	S220	G213R	213	Missense	distal	-7	no	12.161	12.403	PhosphoSitePlus	TCGA;ICGC;COSMIC	7.780	Up-regulation
AGC_Akt_AKT1_ST	Q96BF3	TMIGD2	P31749	AKT1	S220	R217K	217	Missense	distal	-3	no	12.161	7.640	PhosphoSitePlus	TCGA;ICGC;COSMIC	7.780	Loss
AGC_Akt_AKT1_ST	Q96BF3	TMIGD2	P31749	AKT1	S220	T224S	224	Missense	distal	4	no	12.161	12.166	PhosphoSitePlus	TCGA;ICGC;COSMIC	7.780	Up-regulation
AGC_Akt_AKT1_ST	Q96BF3	TMIGD2	P31749	AKT1	S220	G218D	218	Missense	proximal	-2	no	12.161	11.462	PhosphoSitePlus	TCGA;ICGC;COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	Q96BF3	TMIGD2	P31749	AKT1	S220	G218S	218	Missense	proximal	-2	no	12.161	12.855	PhosphoSitePlus	TCGA;ICGC;COSMIC	7.780	Up-regulation
AGC_Akt_AKT1_ST	Q96BF3	TMIGD2	P31749	AKT1	T268	P265R	265	Missense	distal	-3	no	8.266	14.905	EPSD	TCGA;ICGC;COSMIC	7.780	Up-regulation
AGC_Akt_AKT1_ST	Q96BF3	TMIGD2	P31749	AKT1	T268	V261I	261	Missense	distal	-7	no	8.266	8.171	EPSD	TCGA;ICGC;COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	P49760	CLK2	P31749	AKT1	S9	E11K	11	Missense	proximal	2	no	13.250	13.455	EPSD	TCGA;ICGC;COSMIC	7.780	Up-regulation
AGC_Akt_AKT1_ST	P49760	CLK2	P31749	AKT1	S9	R6W	6	Missense	distal	-3	no	13.250	4.309	EPSD	TCGA;ICGC;COSMIC	7.780	Loss
AGC_Akt_AKT1_ST	P49760	CLK2	P31749	AKT1	S9	R15W	15	Missense	distal	6	no	13.250	13.092	EPSD	TCGA;ICGC;COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	P49760	CLK2	P31749	AKT1	S10	E11K	11	Missense	proximal	1	no	9.218	9.382	EPSD	TCGA;ICGC;COSMIC	7.780	Up-regulation
AGC_Akt_AKT1_ST	P49760	CLK2	P31749	AKT1	S10	R6W	6	Missense	distal	-4	no	9.218	7.669	EPSD	TCGA;ICGC;COSMIC	7.780	Loss
AGC_Akt_AKT1_ST	P49760	CLK2	P31749	AKT1	S10	R15W	15	Missense	distal	5	no	9.218	9.124	EPSD	TCGA;ICGC;COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	P49760	CLK2	P31749	AKT1	S14	E11K	11	Missense	distal	-3	no	6.465	8.517	EPSD	TCGA;ICGC;COSMIC	7.780	Gain
AGC_Akt_AKT1_ST	P49760	CLK2	P31749	AKT1	S17	E11K	11	Missense	distal	-6	no	8.588	8.654	EPSD	TCGA;ICGC;COSMIC	7.780	Up-regulation
AGC_Akt_AKT1_ST	P49760	CLK2	P31749	AKT1	S17	R23W	23	Missense	distal	6	no	8.588	8.430	EPSD	TCGA;ICGC;COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	P49760	CLK2	P31749	AKT1	S17	R15W	15	Missense	proximal	-2	no	8.588	7.334	EPSD	TCGA;ICGC;COSMIC	7.780	Loss
AGC_Akt_AKT1_ST	P49760	CLK2	P31749	AKT1	S34	R33H	33	Missense	proximal	-1	no	16.698	16.654	PhosphoSitePlus;EPSD	TCGA;ICGC;COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	P49760	CLK2	P31749	AKT1	S34	R33C	33	Missense	proximal	-1	no	16.698	16.628	PhosphoSitePlus;EPSD	TCGA;ICGC;COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	P49760	CLK2	P31749	AKT1	S34	R29Q	29	Missense	distal	-5	no	16.698	12.471	PhosphoSitePlus;EPSD	TCGA;ICGC;COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	P49760	CLK2	P31749	AKT1	S34	R41W	41	Missense	distal	7	no	16.698	16.600	PhosphoSitePlus;EPSD	TCGA;ICGC	7.780	Down-regulation
AGC_Akt_AKT1_ST	P49760	CLK2	P31749	AKT1	S36	R33H	33	Missense	distal	-3	no	17.235	12.536	EPSD	TCGA;ICGC;COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	P49760	CLK2	P31749	AKT1	S36	R33C	33	Missense	distal	-3	no	17.235	11.061	EPSD	TCGA;ICGC;COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	P49760	CLK2	P31749	AKT1	S36	R29Q	29	Missense	distal	-7	no	17.235	17.040	EPSD	TCGA;ICGC;COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	P49760	CLK2	P31749	AKT1	S36	R41W	41	Missense	distal	5	no	17.235	17.140	EPSD	TCGA;ICGC	7.780	Down-regulation
AGC_Akt_AKT1_ST	P49760	CLK2	P31749	AKT1	S50	S55F	55	Missense	distal	5	no	15.690	15.617	EPSD	TCGA;ICGC;COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	P49760	CLK2	P31749	AKT1	S50	R54H	54	Missense	distal	4	no	15.690	15.874	EPSD	TCGA;ICGC;COSMIC	7.780	Up-regulation
AGC_Akt_AKT1_ST	P49760	CLK2	P31749	AKT1	S50	R47Q	47	Missense	distal	-3	no	15.690	8.478	EPSD	TCGA;ICGC;COSMIC;CCLE	7.780	Down-regulation
AGC_Akt_AKT1_ST	P49760	CLK2	P31749	AKT1	S50	R46Q	46	Missense	distal	-4	no	15.690	15.068	EPSD	TCGA;ICGC;COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	P49760	CLK2	P31749	AKT1	S57	D61N	61	Missense	distal	4	no	11.612	11.497	EPSD	TCGA;ICGC;COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	P49760	CLK2	P31749	AKT1	S57	S55F	55	Missense	proximal	-2	no	11.612	10.745	EPSD	TCGA;ICGC;COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	P49760	CLK2	P31749	AKT1	S57	R54H	54	Missense	distal	-3	no	11.612	6.913	EPSD	TCGA;ICGC;COSMIC	7.780	Loss
AGC_Akt_AKT1_ST	P49760	CLK2	P31749	AKT1	S57	R62C	62	Missense	distal	5	no	11.612	11.486	EPSD	TCGA;ICGC;COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	P49760	CLK2	P31749	AKT1	S57	R62H	62	Missense	distal	5	no	11.612	11.538	EPSD	TCGA;ICGC;COSMIC;CCLE	7.780	Down-regulation
AGC_Akt_AKT1_ST	P49760	CLK2	P31749	AKT1	S106	R112H	112	Missense	distal	6	no	11.851	11.731	EPSD	TCGA;ICGC;COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	P49760	CLK2	P31749	AKT1	S106	E104D	104	Missense	proximal	-2	no	11.851	10.866	EPSD	TCGA;ICGC;COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	P49760	CLK2	P31749	AKT1	S106	R112C	112	Missense	distal	6	no	11.851	11.649	EPSD	TCGA;ICGC;COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	P49760	CLK2	P31749	AKT1	T127	R121W	121	Missense	distal	-6	no	15.979	15.831	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	P49760	CLK2	P31749	AKT1	T127	S125C	125	Missense	proximal	-2	no	15.979	14.326	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	P49760	CLK2	P31749	AKT1	T127	R121Q	121	Missense	distal	-6	no	15.979	15.895	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC;CCLE	7.780	Down-regulation
AGC_Akt_AKT1_ST	P49760	CLK2	P31749	AKT1	T127	R124H	124	Missense	distal	-3	no	15.979	11.280	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC;GDSC;CCLE	7.780	Down-regulation
AGC_Akt_AKT1_ST	P10275	AR	P31749	AKT1	S16	R13G	13	Missense	distal	-3	no	12.059	5.303	EPSD	TCGA;ICGC;COSMIC	7.780	Loss
AGC_Akt_AKT1_ST	P10275	AR	P31749	AKT1	S16	Y19C	19	Missense	distal	3	no	12.059	11.950	EPSD	TCGA;ICGC	7.780	Down-regulation
AGC_Akt_AKT1_ST	P10275	AR	P31749	AKT1	S16	K17N	17	Missense	proximal	1	no	12.059	11.902	EPSD	TCGA;ICGC;COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	P10275	AR	P31749	AKT1	T18	R13G	13	Missense	distal	-5	no	9.744	5.679	EPSD	TCGA;ICGC;COSMIC	7.780	Loss
AGC_Akt_AKT1_ST	P10275	AR	P31749	AKT1	T18	P15L	15	Missense	distal	-3	no	9.744	9.389	EPSD	TCGA;ICGC;COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	P10275	AR	P31749	AKT1	T18	Y19C	19	Missense	proximal	1	no	9.744	9.367	EPSD	TCGA;ICGC	7.780	Down-regulation
AGC_Akt_AKT1_ST	P10275	AR	P31749	AKT1	T18	K17N	17	Missense	proximal	-1	no	9.744	9.719	EPSD	TCGA;ICGC;COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	P10275	AR	P31749	AKT1	S215	A211T	211	Missense	distal	-4	no	14.508	15.286	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	7.780	Up-regulation
AGC_Akt_AKT1_ST	P10275	AR	P31749	AKT1	S215	A211V	211	Missense	distal	-4	no	14.508	14.136	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	P10275	AR	P31749	AKT1	S215	K222N	222	Missense	distal	7	no	14.508	14.473	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	P10275	AR	P31749	AKT1	S648	E645K	645	Missense	distal	-3	no	5.915	7.966	EPSD	TCGA;ICGC;COSMIC	7.780	Gain
AGC_Akt_AKT1_ST	P10275	AR	P31749	AKT1	S792	M788I	788	Missense	distal	-4	no	14.676	14.204	PhosphoSitePlus;EPSD	TCGA;ICGC;COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	P10275	AR	P31749	AKT1	S792	R787Q	787	Missense	distal	-5	no	14.676	10.448	PhosphoSitePlus;EPSD	TCGA;ICGC;COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	P10275	AR	P31749	AKT1	S792	L791I	791	Missense	proximal	-1	no	14.676	14.655	PhosphoSitePlus;EPSD	TCGA;ICGC;COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	P10275	AR	P31749	AKT1	S792	G796V	796	Missense	distal	4	no	14.676	14.682	PhosphoSitePlus;EPSD	TCGA;ICGC;COSMIC	7.780	Up-regulation
AGC_Akt_AKT1_ST	P10275	AR	P31749	AKT1	T851	N849K	849	Missense	proximal	-2	no	7.240	8.176	EPSD	TCGA;ICGC;COSMIC	7.780	Gain
AGC_Akt_AKT1_ST	Q9BRQ0	PYGO2	P31749	AKT1	S48	P53S	53	Missense	distal	5	no	14.059	14.112	PhosphoSitePlus	TCGA;ICGC;COSMIC	7.780	Up-regulation
AGC_Akt_AKT1_ST	Q9BRQ0	PYGO2	P31749	AKT1	S48	Q51R	51	Missense	distal	3	no	14.059	14.116	PhosphoSitePlus	TCGA;ICGC	7.780	Up-regulation
AGC_Akt_AKT1_ST	Q9BRQ0	PYGO2	P31749	AKT1	S48	R46S	46	Missense	proximal	-2	no	14.059	14.248	PhosphoSitePlus	TCGA;ICGC;COSMIC	7.780	Up-regulation
AGC_Akt_AKT1_ST	Q9BRQ0	PYGO2	P31749	AKT1	S48	K43N	43	Missense	distal	-5	no	14.059	11.972	PhosphoSitePlus	TCGA;ICGC;COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	Q9BRQ0	PYGO2	P31749	AKT1	T50	P53S	53	Missense	distal	3	no	11.889	11.970	EPSD	TCGA;ICGC;COSMIC	7.780	Up-regulation
AGC_Akt_AKT1_ST	Q9BRQ0	PYGO2	P31749	AKT1	T50	Q51R	51	Missense	proximal	1	no	11.889	12.184	EPSD	TCGA;ICGC	7.780	Up-regulation
AGC_Akt_AKT1_ST	Q9BRQ0	PYGO2	P31749	AKT1	T50	R46S	46	Missense	distal	-4	no	11.889	11.803	EPSD	TCGA;ICGC;COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	Q9BRQ0	PYGO2	P31749	AKT1	T50	K43N	43	Missense	distal	-7	no	11.889	11.732	EPSD	TCGA;ICGC;COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	Q9BRQ0	PYGO2	P31749	AKT1	S56	Q51R	51	Missense	distal	-5	no	5.310	9.537	EPSD	TCGA;ICGC	7.780	Gain
AGC_Akt_AKT1_ST	Q13950	RUNX2	P31749	AKT1	S28	P29T	29	Missense	proximal	1	no	13.000	13.349	EPSD;PhosphoSitePlus	TCGA;COSMIC	7.780	Up-regulation
AGC_Akt_AKT1_ST	Q13950	RUNX2	P31749	AKT1	S28	P29S	29	Missense	proximal	1	no	13.000	13.156	EPSD;PhosphoSitePlus	TCGA;COSMIC	7.780	Up-regulation
AGC_Akt_AKT1_ST	Q13950	RUNX2	P31749	AKT1	S31	P29T	29	Missense	proximal	-2	no	8.646	9.404	EPSD	TCGA;COSMIC	7.780	Up-regulation
AGC_Akt_AKT1_ST	Q13950	RUNX2	P31749	AKT1	S31	P29S	29	Missense	proximal	-2	no	8.646	9.470	EPSD	TCGA;COSMIC	7.780	Up-regulation
AGC_Akt_AKT1_ST	Q13950	RUNX2	P31749	AKT1	S196	R193Q	193	Missense	distal	-3	no	11.166	3.955	EPSD;PhosphoSitePlus	TCGA;COSMIC	7.780	Loss
AGC_Akt_AKT1_ST	Q13950	RUNX2	P31749	AKT1	S196	V203I	203	Missense	distal	7	no	11.166	11.123	EPSD;PhosphoSitePlus	TCGA;COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	Q13950	RUNX2	P31749	AKT1	S196	K195N	195	Missense	proximal	-1	no	11.166	11.141	EPSD;PhosphoSitePlus	TCGA;COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	Q13950	RUNX2	P31749	AKT1	S196	T202A	202	Missense	distal	6	no	11.166	11.063	EPSD;PhosphoSitePlus	TCGA;COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	Q13950	RUNX2	P31749	AKT1	S196	R190W	190	Missense	distal	-6	no	11.166	11.018	EPSD;PhosphoSitePlus	TCGA;COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	Q13950	RUNX2	P31749	AKT1	T198	R193Q	193	Missense	distal	-5	no	10.635	6.408	EPSD;PhosphoSitePlus	TCGA;COSMIC	7.780	Loss
AGC_Akt_AKT1_ST	Q13950	RUNX2	P31749	AKT1	T198	V203I	203	Missense	distal	5	no	10.635	10.598	EPSD;PhosphoSitePlus	TCGA;COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	Q13950	RUNX2	P31749	AKT1	T198	K195N	195	Missense	distal	-3	no	10.635	7.679	EPSD;PhosphoSitePlus	TCGA;COSMIC	7.780	Loss
AGC_Akt_AKT1_ST	Q13950	RUNX2	P31749	AKT1	T198	T202A	202	Missense	distal	4	no	10.635	10.764	EPSD;PhosphoSitePlus	TCGA;COSMIC	7.780	Up-regulation
AGC_Akt_AKT1_ST	Q13950	RUNX2	P31749	AKT1	T220	R225L	225	Missense	distal	5	no	8.535	8.461	EPSD	TCGA;COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	Q13950	RUNX2	P31749	AKT1	T220	D222H	222	Missense	proximal	2	no	8.535	8.601	EPSD	TCGA;COSMIC	7.780	Up-regulation
AGC_Akt_AKT1_ST	Q13950	RUNX2	P31749	AKT1	T220	R225W	225	Missense	distal	5	no	8.535	8.440	EPSD	TCGA	7.780	Down-regulation
AGC_Akt_AKT1_ST	Q13950	RUNX2	P31749	AKT1	S294	P296S	296	Missense	proximal	2	no	8.071	8.407	EPSD	TCGA;COSMIC	7.780	Up-regulation
AGC_Akt_AKT1_ST	Q13950	RUNX2	P31749	AKT1	S340	V335A	335	Missense	distal	-5	no	9.152	9.612	EPSD	TCGA	7.780	Up-regulation
AGC_Akt_AKT1_ST	Q13950	RUNX2	P31749	AKT1	S340	R337M	337	Missense	distal	-3	no	9.152	1.646	EPSD	TCGA;COSMIC	7.780	Loss
AGC_Akt_AKT1_ST	Q13950	RUNX2	P31749	AKT1	S340	R338H	338	Missense	proximal	-2	no	9.152	8.291	EPSD	TCGA;COSMIC;CCLE	7.780	Down-regulation
AGC_Akt_AKT1_ST	Q13950	RUNX2	P31749	AKT1	S340	D341Y	341	Missense	proximal	1	no	9.152	9.357	EPSD	TCGA;COSMIC	7.780	Up-regulation
AGC_Akt_AKT1_ST	Q13950	RUNX2	P31749	AKT1	S503	V506F	506	Missense	distal	3	no	8.669	8.661	EPSD	TCGA;COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	Q13950	RUNX2	P31749	AKT1	S503	S503Y	503	Missense	central	0	yes	8.669	0.000	EPSD	TCGA;COSMIC	7.780	Loss
AGC_Akt_AKT1_ST	O60825	PFKFB2	P31749	AKT1	S29	W30L	30	Missense	proximal	1	no	8.511	8.758	EPSD	TCGA;COSMIC	7.780	Up-regulation
AGC_Akt_AKT1_ST	O60825	PFKFB2	P31749	AKT1	T52	R49W	49	Missense	distal	-3	no	10.138	1.198	EPSD	TCGA;COSMIC	7.780	Loss
AGC_Akt_AKT1_ST	O60825	PFKFB2	P31749	AKT1	T59	R60C	60	Missense	proximal	1	no	8.764	8.236	EPSD	TCGA;COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	O60825	PFKFB2	P31749	AKT1	S84	R78W	78	Missense	distal	-6	no	8.731	8.584	EPSD	TCGA;COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	O60825	PFKFB2	P31749	AKT1	S84	R78Q	78	Missense	distal	-6	no	8.731	8.647	EPSD	TCGA	7.780	Down-regulation
AGC_Akt_AKT1_ST	O60825	PFKFB2	P31749	AKT1	S483	R478H	478	Missense	distal	-5	no	16.631	13.536	EPSD;PhosphoSitePlus	TCGA;COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	O60825	PFKFB2	P31749	AKT1	S483	G485W	485	Missense	proximal	2	no	16.631	16.336	EPSD;PhosphoSitePlus	TCGA;COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	O60825	PFKFB2	P31749	AKT1	S483	R480I	480	Missense	distal	-3	no	16.631	9.550	EPSD;PhosphoSitePlus	TCGA;COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	O60825	PFKFB2	P31749	AKT1	S483	V484I	484	Missense	proximal	1	no	16.631	16.384	EPSD;PhosphoSitePlus	TCGA;COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	O60825	PFKFB2	P31749	AKT1	S493	R496P	496	Missense	distal	3	no	8.042	7.977	EPSD	TCGA;COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	O60825	PFKFB2	P31749	AKT1	S493	D499V	499	Missense	distal	6	no	8.042	8.078	EPSD	TCGA;COSMIC	7.780	Up-regulation
AGC_Akt_AKT1_ST	O60825	PFKFB2	P31749	AKT1	S493	L495F	495	Missense	proximal	2	no	8.042	8.010	EPSD	TCGA;COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	Q14CB8	ARHGAP19	P31749	AKT1	S95	G90R	90	Missense	distal	-5	no	4.147	8.211	EPSD	TCGA;COSMIC	7.780	Gain
AGC_Akt_AKT1_ST	Q14CB8	ARHGAP19	P31749	AKT1	S412	K416M	416	Missense	distal	4	no	8.697	8.883	EPSD	TCGA;ICGC;COSMIC	7.780	Up-regulation
AGC_Akt_AKT1_ST	Q14CB8	ARHGAP19	P31749	AKT1	S412	S412F	412	Missense	central	0	yes	8.697	0.000	EPSD	TCGA;ICGC;COSMIC	7.780	Loss
AGC_Akt_AKT1_ST	Q14CB8	ARHGAP19	P31749	AKT1	S412	R419C	419	Missense	distal	7	no	8.697	8.567	EPSD	TCGA;ICGC;COSMIC;GDSC;CCLE	7.780	Down-regulation
AGC_Akt_AKT1_ST	Q14CB8	ARHGAP19	P31749	AKT1	S420	K416M	416	Missense	distal	-4	no	13.320	12.338	EPSD	TCGA;ICGC;COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	Q14CB8	ARHGAP19	P31749	AKT1	S420	R419C	419	Missense	proximal	-1	no	13.320	13.249	EPSD	TCGA;ICGC;COSMIC;GDSC;CCLE	7.780	Down-regulation
AGC_Akt_AKT1_ST	Q14CB8	ARHGAP19	P31749	AKT1	S422	K416M	416	Missense	distal	-6	no	15.684	15.602	PhosphoSitePlus	TCGA;ICGC;COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	Q14CB8	ARHGAP19	P31749	AKT1	S422	R429Q	429	Missense	distal	7	no	15.684	15.629	PhosphoSitePlus	TCGA;ICGC	7.780	Down-regulation
AGC_Akt_AKT1_ST	Q14CB8	ARHGAP19	P31749	AKT1	S422	R419C	419	Missense	distal	-3	no	15.684	9.511	PhosphoSitePlus	TCGA;ICGC;COSMIC;GDSC;CCLE	7.780	Down-regulation
AGC_Akt_AKT1_ST	Q14CB8	ARHGAP19	P31749	AKT1	S424	R429Q	429	Missense	distal	5	no	16.448	16.397	EPSD	TCGA;ICGC	7.780	Down-regulation
AGC_Akt_AKT1_ST	Q14CB8	ARHGAP19	P31749	AKT1	S424	R419C	419	Missense	distal	-5	no	16.448	12.371	EPSD	TCGA;ICGC;COSMIC;GDSC;CCLE	7.780	Down-regulation
AGC_Akt_AKT1_ST	Q14CB8	ARHGAP19	P31749	AKT1	T446	K440N	440	Missense	distal	-6	no	8.349	8.282	EPSD	TCGA;ICGC;COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	Q14CB8	ARHGAP19	P31749	AKT1	T446	P445L	445	Missense	proximal	-1	no	8.349	8.350	EPSD	TCGA;ICGC;COSMIC	7.780	Up-regulation
AGC_Akt_AKT1_ST	Q14CB8	ARHGAP19	P31749	AKT1	T446	N444I	444	Missense	proximal	-2	no	8.349	7.794	EPSD	TCGA;ICGC;COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	Q14CB8	ARHGAP19	P31749	AKT1	S468	E461Q	461	Missense	distal	-7	no	9.604	9.615	EPSD	TCGA;ICGC;COSMIC	7.780	Up-regulation
AGC_Akt_AKT1_ST	Q14CB8	ARHGAP19	P31749	AKT1	S468	S468C	468	Missense	central	0	yes	9.604	0.000	EPSD	TCGA;ICGC;COSMIC	7.780	Loss
AGC_Akt_AKT1_ST	Q14CB8	ARHGAP19	P31749	AKT1	S468	E461K	461	Missense	distal	-7	no	9.604	9.796	EPSD	TCGA;ICGC;COSMIC	7.780	Up-regulation
AGC_Akt_AKT1_ST	Q96ST2	IWS1	P31749	AKT1	T42	G39R	39	Missense	distal	-3	no	6.144	12.900	EPSD	TCGA;ICGC;COSMIC	7.780	Gain
AGC_Akt_AKT1_ST	Q96ST2	IWS1	P31749	AKT1	S44	G39R	39	Missense	distal	-5	no	7.564	11.629	EPSD	TCGA;ICGC;COSMIC	7.780	Gain
AGC_Akt_AKT1_ST	Q96ST2	IWS1	P31749	AKT1	S131	K127T	127	Missense	distal	-4	no	9.249	9.232	EPSD	TCGA;ICGC	7.780	Down-regulation
AGC_Akt_AKT1_ST	Q96ST2	IWS1	P31749	AKT1	S131	E136Q	136	Missense	distal	5	no	9.249	9.238	EPSD	TCGA;ICGC;COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	Q96ST2	IWS1	P31749	AKT1	S131	R126K	126	Missense	distal	-5	no	9.249	6.851	EPSD	TCGA;ICGC;COSMIC	7.780	Loss
AGC_Akt_AKT1_ST	Q96ST2	IWS1	P31749	AKT1	S131	E134V	134	Missense	distal	3	no	9.249	9.200	EPSD	TCGA;ICGC	7.780	Down-regulation
AGC_Akt_AKT1_ST	Q96ST2	IWS1	P31749	AKT1	S157	S159F	159	Missense	proximal	2	no	7.937	7.359	EPSD	TCGA;ICGC;COSMIC;GDSC;CCLE	7.780	Loss
AGC_Akt_AKT1_ST	Q96ST2	IWS1	P31749	AKT1	S157	S159Y	159	Missense	proximal	2	no	7.937	7.564	EPSD	TCGA;ICGC;COSMIC	7.780	Loss
AGC_Akt_AKT1_ST	Q96ST2	IWS1	P31749	AKT1	S157	S159C	159	Missense	proximal	2	no	7.937	7.112	EPSD	TCGA;ICGC;COSMIC	7.780	Loss
AGC_Akt_AKT1_ST	Q96ST2	IWS1	P31749	AKT1	S157	V151I	151	Missense	distal	-6	no	7.937	7.892	EPSD	TCGA	7.780	Down-regulation
AGC_Akt_AKT1_ST	Q96ST2	IWS1	P31749	AKT1	S329	E336V	336	Missense	distal	7	no	8.673	8.652	EPSD	TCGA;ICGC;COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	Q96ST2	IWS1	P31749	AKT1	S362	M355T	355	Missense	distal	-7	no	11.875	12.142	EPSD	TCGA;ICGC;COSMIC	7.780	Up-regulation
AGC_Akt_AKT1_ST	Q96ST2	IWS1	P31749	AKT1	S415	A417V	417	Missense	proximal	2	no	12.216	12.053	EPSD	TCGA;COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	Q96ST2	IWS1	P31749	AKT1	T435	K434N	434	Missense	proximal	-1	no	11.271	11.246	EPSD	TCGA;COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	Q96ST2	IWS1	P31749	AKT1	T435	S438F	438	Missense	distal	3	no	11.271	11.172	EPSD	TCGA;COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	Q96ST2	IWS1	P31749	AKT1	S511	D510N	510	Missense	proximal	-1	no	8.095	8.125	EPSD	TCGA;ICGC;COSMIC	7.780	Up-regulation
AGC_Akt_AKT1_ST	Q96ST2	IWS1	P31749	AKT1	S511	A508P	508	Missense	distal	-3	no	8.095	7.758	EPSD	TCGA;ICGC;COSMIC	7.780	Loss
AGC_Akt_AKT1_ST	Q96ST2	IWS1	P31749	AKT1	S720	R715Q	715	Missense	distal	-5	no	16.574	12.346	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC;GDSC;CCLE	7.780	Down-regulation
AGC_Akt_AKT1_ST	Q96ST2	IWS1	P31749	AKT1	T796	D797N	797	Missense	proximal	1	no	11.209	11.334	EPSD	TCGA;ICGC;COSMIC	7.780	Up-regulation
AGC_Akt_AKT1_ST	Q96ST2	IWS1	P31749	AKT1	S811	A807T	807	Missense	distal	-4	no	7.453	8.231	EPSD	TCGA;ICGC;COSMIC	7.780	Gain
AGC_Akt_AKT1_ST	O60285	NUAK1	P31749	AKT1	S266	R263Q	263	Missense	distal	-3	no	11.701	4.490	EPSD	TCGA;ICGC;COSMIC	7.780	Loss
AGC_Akt_AKT1_ST	O60285	NUAK1	P31749	AKT1	S266	R263W	263	Missense	distal	-3	no	11.701	2.761	EPSD	TCGA	7.780	Loss
AGC_Akt_AKT1_ST	O60285	NUAK1	P31749	AKT1	S266	S266R	266	Missense	central	0	yes	11.701	0.000	EPSD	TCGA;ICGC;COSMIC	7.780	Loss
AGC_Akt_AKT1_ST	O60285	NUAK1	P31749	AKT1	S266	S266N	266	Missense	central	0	yes	11.701	0.000	EPSD	TCGA;ICGC;COSMIC	7.780	Loss
AGC_Akt_AKT1_ST	O60285	NUAK1	P31749	AKT1	S413	V420A	420	Missense	distal	7	no	11.837	11.841	EPSD	TCGA;ICGC;COSMIC	7.780	Up-regulation
AGC_Akt_AKT1_ST	O60285	NUAK1	P31749	AKT1	S413	R410H	410	Missense	distal	-3	no	11.837	7.138	EPSD	TCGA;ICGC;COSMIC;GDSC;CCLE	7.780	Loss
AGC_Akt_AKT1_ST	O60285	NUAK1	P31749	AKT1	S413	E408K	408	Missense	distal	-5	no	11.837	13.535	EPSD	TCGA;ICGC;COSMIC	7.780	Up-regulation
AGC_Akt_AKT1_ST	O60285	NUAK1	P31749	AKT1	S516	K522E	522	Missense	distal	6	no	8.923	8.854	EPSD	TCGA;ICGC;COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	O60285	NUAK1	P31749	AKT1	S516	R520Q	520	Missense	distal	4	no	8.923	9.047	EPSD	TCGA;COSMIC	7.780	Up-regulation
AGC_Akt_AKT1_ST	O60285	NUAK1	P31749	AKT1	S518	K522E	522	Missense	distal	4	no	7.980	8.081	EPSD	TCGA;ICGC;COSMIC	7.780	Up-regulation
AGC_Akt_AKT1_ST	O60285	NUAK1	P31749	AKT1	S518	R520Q	520	Missense	proximal	2	no	7.980	7.862	EPSD	TCGA;COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	O60285	NUAK1	P31749	AKT1	S566	R567C	567	Missense	proximal	1	no	12.954	12.425	EPSD	TCGA;ICGC;COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	O60285	NUAK1	P31749	AKT1	S566	R567H	567	Missense	proximal	1	no	12.954	12.631	EPSD	TCGA;ICGC;COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	O60285	NUAK1	P31749	AKT1	S566	S566N	566	Missense	central	0	yes	12.954	0.000	EPSD	TCGA;ICGC	7.780	Loss
AGC_Akt_AKT1_ST	O60285	NUAK1	P31749	AKT1	S566	R563W	563	Missense	distal	-3	no	12.954	4.013	EPSD	TCGA;ICGC;COSMIC	7.780	Loss
AGC_Akt_AKT1_ST	O60285	NUAK1	P31749	AKT1	S566	S566I	566	Missense	central	0	yes	12.954	0.000	EPSD	TCGA;ICGC;COSMIC	7.780	Loss
AGC_Akt_AKT1_ST	O60285	NUAK1	P31749	AKT1	S570	R567C	567	Missense	distal	-3	no	12.692	6.519	EPSD	TCGA;ICGC;COSMIC	7.780	Loss
AGC_Akt_AKT1_ST	O60285	NUAK1	P31749	AKT1	S570	S576R	576	Missense	distal	6	no	12.692	12.691	EPSD	TCGA;ICGC;COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	O60285	NUAK1	P31749	AKT1	S570	R567H	567	Missense	distal	-3	no	12.692	7.994	EPSD	TCGA;ICGC;COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	O60285	NUAK1	P31749	AKT1	S570	S566N	566	Missense	distal	-4	no	12.692	12.125	EPSD	TCGA;ICGC	7.780	Down-regulation
AGC_Akt_AKT1_ST	O60285	NUAK1	P31749	AKT1	S570	R563W	563	Missense	distal	-7	no	12.692	12.269	EPSD	TCGA;ICGC;COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	O60285	NUAK1	P31749	AKT1	S570	S566I	566	Missense	distal	-4	no	12.692	11.311	EPSD	TCGA;ICGC;COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	O60285	NUAK1	P31749	AKT1	S570	V577M	577	Missense	distal	7	no	12.692	12.688	EPSD	TCGA;ICGC;COSMIC;GDSC;CCLE	7.780	Down-regulation
AGC_Akt_AKT1_ST	O60285	NUAK1	P31749	AKT1	S570	D574N	574	Missense	distal	4	no	12.692	12.577	EPSD	TCGA;ICGC;COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	O60285	NUAK1	P31749	AKT1	S600	P593S	593	Missense	distal	-7	no	14.420	14.614	PhosphoSitePlus	TCGA;ICGC;COSMIC	7.780	Up-regulation
AGC_Akt_AKT1_ST	O60285	NUAK1	P31749	AKT1	S600	R599C	599	Missense	proximal	-1	no	14.420	14.350	PhosphoSitePlus	TCGA;ICGC;COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	O60285	NUAK1	P31749	AKT1	S600	R599H	599	Missense	proximal	-1	no	14.420	14.376	PhosphoSitePlus	TCGA;ICGC;COSMIC;CCLE	7.780	Down-regulation
AGC_Akt_AKT1_ST	O60285	NUAK1	P31749	AKT1	S636	R631W	631	Missense	distal	-5	no	8.216	2.696	EPSD	TCGA;ICGC;COSMIC	7.780	Loss
AGC_Akt_AKT1_ST	O60285	NUAK1	P31749	AKT1	S636	M643I	643	Missense	distal	7	no	8.216	8.178	EPSD	TCGA;ICGC;COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	O60285	NUAK1	P31749	AKT1	S636	R631Q	631	Missense	distal	-5	no	8.216	3.989	EPSD	TCGA;ICGC;COSMIC	7.780	Loss
AGC_Akt_AKT1_ST	O60285	NUAK1	P31749	AKT1	S636	D642N	642	Missense	distal	6	no	8.216	8.298	EPSD	TCGA;ICGC;COSMIC	7.780	Up-regulation
AGC_Akt_AKT1_ST	Q5XUX0	FBXO31	P31749	AKT1	T127	R122Q	122	Missense	distal	-5	no	8.142	3.914	EPSD	TCGA;ICGC;COSMIC	7.780	Loss
AGC_Akt_AKT1_ST	Q5XUX0	FBXO31	P31749	AKT1	T127	R132W	132	Missense	distal	5	no	8.142	8.047	EPSD	TCGA;ICGC;COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	Q5XUX0	FBXO31	P31749	AKT1	T127	V134I	134	Missense	distal	7	no	8.142	8.099	EPSD	TCGA;ICGC;COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	Q5XUX0	FBXO31	P31749	AKT1	S403	P397S	397	Missense	distal	-6	no	8.709	8.773	EPSD	TCGA;ICGC;COSMIC	7.780	Up-regulation
AGC_Akt_AKT1_ST	Q5XUX0	FBXO31	P31749	AKT1	S403	R398W	398	Missense	distal	-5	no	8.709	3.189	EPSD	TCGA;ICGC;COSMIC	7.780	Loss
AGC_Akt_AKT1_ST	Q5XUX0	FBXO31	P31749	AKT1	S403	E410D	410	Missense	distal	7	no	8.709	8.666	EPSD	TCGA;ICGC;COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	Q5XUX0	FBXO31	P31749	AKT1	S403	R398Q	398	Missense	distal	-5	no	8.709	4.482	EPSD	TCGA;ICGC;COSMIC	7.780	Loss
AGC_Akt_AKT1_ST	Q9Y283	INVS	P31749	AKT1	S126	R123Q	123	Missense	distal	-3	no	11.587	4.376	EPSD	TCGA;ICGC	7.780	Loss
AGC_Akt_AKT1_ST	Q9Y283	INVS	P31749	AKT1	S126	R125M	125	Missense	proximal	-1	no	11.587	11.547	EPSD	TCGA;ICGC;COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	Q9Y283	INVS	P31749	AKT1	T864	E863D	863	Missense	proximal	-1	no	12.036	12.002	EPSD;PhosphoSitePlus	TCGA;ICGC	7.780	Down-regulation
AGC_Akt_AKT1_ST	Q9Y283	INVS	P31749	AKT1	T864	E869K	869	Missense	distal	5	no	12.036	12.070	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	7.780	Up-regulation
AGC_Akt_AKT1_ST	Q9Y283	INVS	P31749	AKT1	S865	E863D	863	Missense	proximal	-2	no	10.087	9.102	EPSD;PhosphoSitePlus	TCGA;ICGC	7.780	Down-regulation
AGC_Akt_AKT1_ST	Q9Y283	INVS	P31749	AKT1	S865	E869K	869	Missense	distal	4	no	10.087	9.986	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	Q9Y283	INVS	P31749	AKT1	T866	E863D	863	Missense	distal	-3	no	9.905	10.526	PhosphoSitePlus;EPSD	TCGA;ICGC	7.780	Up-regulation
AGC_Akt_AKT1_ST	Q9Y283	INVS	P31749	AKT1	T866	E869K	869	Missense	distal	3	no	9.905	9.948	PhosphoSitePlus;EPSD	TCGA;ICGC;COSMIC	7.780	Up-regulation
AGC_Akt_AKT1_ST	Q9Y283	INVS	P31749	AKT1	S1023	S1024F	1024	Missense	proximal	1	no	9.831	9.849	EPSD	TCGA;COSMIC	7.780	Up-regulation
AGC_Akt_AKT1_ST	Q9Y283	INVS	P31749	AKT1	S1023	S1024Y	1024	Missense	proximal	1	no	9.831	9.824	EPSD	TCGA;COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	Q9Y283	INVS	P31749	AKT1	S1030	S1024F	1024	Missense	distal	-6	no	9.814	9.740	EPSD	TCGA;COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	Q9Y283	INVS	P31749	AKT1	S1030	S1024Y	1024	Missense	distal	-6	no	9.814	9.755	EPSD	TCGA;COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	Q9Y283	INVS	P31749	AKT1	S1030	C1036R	1036	Missense	distal	6	no	9.814	10.016	EPSD	TCGA	7.780	Up-regulation
AGC_Akt_AKT1_ST	Q9Y283	INVS	P31749	AKT1	S1032	C1036R	1036	Missense	distal	4	no	8.309	7.975	EPSD	TCGA	7.780	Down-regulation
AGC_Akt_AKT1_ST	Q9Y283	INVS	P31749	AKT1	S1050	S1050F	1050	Missense	central	0	yes	14.182	0.000	EPSD	TCGA	7.780	Loss
AGC_Akt_AKT1_ST	Q9Y283	INVS	P31749	AKT1	S1055	S1050F	1050	Missense	distal	-5	no	7.215	8.163	EPSD	TCGA	7.780	Gain
AGC_Akt_AKT1_ST	Q9UPY5	SLC7A11	P31749	AKT1	S8	V6A	6	Missense	proximal	-2	no	9.813	10.551	EPSD	TCGA;ICGC;COSMIC	7.780	Up-regulation
AGC_Akt_AKT1_ST	Q9UPY5	SLC7A11	P31749	AKT1	S8	S8F	8	Missense	central	0	yes	9.813	0.000	EPSD	TCGA;ICGC;COSMIC	7.780	Loss
AGC_Akt_AKT1_ST	Q9UPY5	SLC7A11	P31749	AKT1	S8	G13E	13	Missense	distal	5	no	9.813	9.844	EPSD	TCGA;ICGC;COSMIC	7.780	Up-regulation
AGC_Akt_AKT1_ST	Q9UPY5	SLC7A11	P31749	AKT1	S11	S8F	8	Missense	distal	-3	no	5.849	8.031	EPSD	TCGA;ICGC;COSMIC	7.780	Gain
AGC_Akt_AKT1_ST	Q9UPY5	SLC7A11	P31749	AKT1	S26	N19H	19	Missense	distal	-7	no	10.440	10.309	PhosphoSitePlus	TCGA;ICGC;COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	Q9UPY5	SLC7A11	P31749	AKT1	S26	P25L	25	Missense	proximal	-1	no	10.440	10.441	PhosphoSitePlus	TCGA;ICGC;COSMIC	7.780	Up-regulation
AGC_Akt_AKT1_ST	Q9UPY5	SLC7A11	P31749	AKT1	S26	K30N	30	Missense	distal	4	no	10.440	10.572	PhosphoSitePlus	TCGA;ICGC	7.780	Up-regulation
AGC_Akt_AKT1_ST	Q9UPY5	SLC7A11	P31749	AKT1	S26	P25S	25	Missense	proximal	-1	no	10.440	10.469	PhosphoSitePlus	TCGA;ICGC	7.780	Up-regulation
AGC_Akt_AKT1_ST	Q9UPY5	SLC7A11	P31749	AKT1	S51	T56I	56	Missense	distal	5	no	9.889	9.792	EPSD	TCGA;ICGC;COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	O43524	FOXO3	P31749	AKT1	S75	D68Y	68	Missense	distal	-7	no	12.604	12.769	EPSD	TCGA;ICGC;COSMIC	7.780	Up-regulation
AGC_Akt_AKT1_ST	O43524	FOXO3	P31749	AKT1	S253	R248Q	248	Missense	distal	-5	no	16.516	12.289	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	O43524	FOXO3	P31749	AKT1	S253	R250W	250	Missense	distal	-3	no	16.516	7.576	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	7.780	Loss
AGC_Akt_AKT1_ST	O43524	FOXO3	P31749	AKT1	S253	R250Q	250	Missense	distal	-3	no	16.516	9.305	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	O43524	FOXO3	P31749	AKT1	T313	R310C	310	Missense	distal	-3	no	10.817	4.643	EPSD	TCGA;ICGC;COSMIC	7.780	Loss
AGC_Akt_AKT1_ST	O43524	FOXO3	P31749	AKT1	T313	D308Y	308	Missense	distal	-5	no	10.817	10.254	EPSD	TCGA;ICGC;COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	O43524	FOXO3	P31749	AKT1	T313	S315F	315	Missense	proximal	2	no	10.817	10.239	EPSD	TCGA;ICGC;COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	O43524	FOXO3	P31749	AKT1	T313	R312C	312	Missense	proximal	-1	no	10.817	10.746	EPSD	TCGA;ICGC;COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	O43524	FOXO3	P31749	AKT1	S315	R310C	310	Missense	distal	-5	no	16.048	11.971	EPSD	TCGA;ICGC;COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	O43524	FOXO3	P31749	AKT1	S315	D308Y	308	Missense	distal	-7	no	16.048	16.213	EPSD	TCGA;ICGC;COSMIC	7.780	Up-regulation
AGC_Akt_AKT1_ST	O43524	FOXO3	P31749	AKT1	S315	S315F	315	Missense	central	0	yes	16.048	0.000	EPSD	TCGA;ICGC;COSMIC	7.780	Loss
AGC_Akt_AKT1_ST	O43524	FOXO3	P31749	AKT1	S315	R312C	312	Missense	distal	-3	no	16.048	9.874	EPSD	TCGA;ICGC;COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	O43524	FOXO3	P31749	AKT1	S413	S412C	412	Missense	proximal	-1	no	11.407	11.347	EPSD	TCGA;ICGC;COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	O43524	FOXO3	P31749	AKT1	S439	G436R	436	Missense	distal	-3	no	3.438	10.194	EPSD	TCGA;ICGC;COSMIC;GDSC;CCLE	7.780	Gain
AGC_Akt_AKT1_ST	O43524	FOXO3	P31749	AKT1	S551	S553Y	553	Missense	proximal	2	no	11.257	10.885	EPSD	TCGA;ICGC;COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	O43524	FOXO3	P31749	AKT1	S553	S560I	560	Missense	distal	7	no	9.351	9.254	EPSD	TCGA;ICGC;COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	O43524	FOXO3	P31749	AKT1	S553	S553Y	553	Missense	central	0	yes	9.351	0.000	EPSD	TCGA;ICGC;COSMIC	7.780	Loss
AGC_Akt_AKT1_ST	O43524	FOXO3	P31749	AKT1	S666	A665S	665	Missense	proximal	-1	no	8.863	8.883	EPSD	TCGA;ICGC;COSMIC	7.780	Up-regulation
AGC_Akt_AKT1_ST	O43524	FOXO3	P31749	AKT1	S666	S669R	669	Missense	distal	3	no	8.863	8.846	EPSD	TCGA;ICGC	7.780	Down-regulation
AGC_Akt_AKT1_ST	O43524	FOXO3	P31749	AKT1	S667	A665S	665	Missense	proximal	-2	no	7.543	7.995	EPSD	TCGA;ICGC;COSMIC	7.780	Gain
AGC_Akt_AKT1_ST	P46527	CDKN1B	P31749	AKT1	S10	S7C	7	Missense	distal	-3	no	9.798	11.401	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	7.780	Up-regulation
AGC_Akt_AKT1_ST	P46527	CDKN1B	P31749	AKT1	S10	G9W	9	Missense	proximal	-1	no	9.798	9.777	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	P46527	CDKN1B	P31749	AKT1	S12	S7C	7	Missense	distal	-5	no	7.429	7.823	EPSD	TCGA;ICGC;COSMIC	7.780	Gain
AGC_Akt_AKT1_ST	P46527	CDKN1B	P31749	AKT1	T157	S161C	161	Missense	distal	4	no	13.829	14.174	PhosphoSitePlus;EPSD	TCGA;ICGC;COSMIC	7.780	Up-regulation
AGC_Akt_AKT1_ST	P46527	CDKN1B	P31749	AKT1	T157	S161Y	161	Missense	distal	4	no	13.829	13.965	PhosphoSitePlus;EPSD	TCGA;ICGC	7.780	Up-regulation
AGC_Akt_AKT1_ST	P46527	CDKN1B	P31749	AKT1	T157	G150E	150	Missense	distal	-7	no	13.829	13.865	PhosphoSitePlus;EPSD	TCGA;ICGC;COSMIC	7.780	Up-regulation
AGC_Akt_AKT1_ST	P84103	SRSF3	P31749	AKT1	S5	C6F	6	Missense	proximal	1	no	7.722	8.123	EPSD	TCGA;ICGC;COSMIC	7.780	Gain
AGC_Akt_AKT1_ST	P84103	SRSF3	P31749	AKT1	S95	P94S	94	Missense	proximal	-1	no	8.835	8.864	EPSD	TCGA;ICGC;COSMIC	7.780	Up-regulation
AGC_Akt_AKT1_ST	P84103	SRSF3	P31749	AKT1	S95	R90C	90	Missense	distal	-5	no	8.835	4.758	EPSD	TCGA;ICGC;COSMIC;GDSC;CCLE	7.780	Loss
AGC_Akt_AKT1_ST	P84103	SRSF3	P31749	AKT1	S95	R88I	88	Missense	distal	-7	no	8.835	8.406	EPSD	TCGA;ICGC;COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	P84103	SRSF3	P31749	AKT1	S95	R99H	99	Missense	distal	4	no	8.835	9.019	EPSD	TCGA;ICGC;COSMIC;GDSC;CCLE	7.780	Up-regulation
AGC_Akt_AKT1_ST	P84103	SRSF3	P31749	AKT1	S108	R105C	105	Missense	distal	-3	no	10.457	4.283	EPSD	TCGA;ICGC;COSMIC	7.780	Loss
AGC_Akt_AKT1_ST	P84103	SRSF3	P31749	AKT1	S108	R113C	113	Missense	distal	5	no	10.457	10.331	EPSD	TCGA;ICGC;COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	P84103	SRSF3	P31749	AKT1	S115	P116L	116	Missense	proximal	1	no	12.485	12.738	EPSD	TCGA;ICGC;COSMIC	7.780	Up-regulation
AGC_Akt_AKT1_ST	P84103	SRSF3	P31749	AKT1	S115	R113C	113	Missense	proximal	-2	no	12.485	11.020	EPSD	TCGA;ICGC;COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	P84103	SRSF3	P31749	AKT1	S120	P116L	116	Missense	distal	-4	no	11.984	11.596	EPSD	TCGA;ICGC;COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	P84103	SRSF3	P31749	AKT1	S120	R113C	113	Missense	distal	-7	no	11.984	11.505	EPSD	TCGA;ICGC;COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	P84103	SRSF3	P31749	AKT1	S122	P116L	116	Missense	distal	-6	no	16.112	16.125	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	7.780	Up-regulation
AGC_Akt_AKT1_ST	P84103	SRSF3	P31749	AKT1	S128	R135K	135	Missense	distal	7	no	17.309	17.301	PhosphoSitePlus;EPSD	TCGA;ICGC;COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	P84103	SRSF3	P31749	AKT1	S130	R135K	135	Missense	distal	5	no	16.169	16.163	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	P84103	SRSF3	P31749	AKT1	S138	R135K	135	Missense	distal	-3	no	16.412	11.891	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	P84103	SRSF3	P31749	AKT1	S138	S138L	138	Missense	central	0	yes	16.412	0.000	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	7.780	Loss
AGC_Akt_AKT1_ST	P84103	SRSF3	P31749	AKT1	S140	R135K	135	Missense	distal	-5	no	16.590	14.192	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	P84103	SRSF3	P31749	AKT1	S140	S138L	138	Missense	proximal	-2	no	16.590	15.733	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	P84103	SRSF3	P31749	AKT1	S148	R155C	155	Missense	distal	7	no	13.610	13.480	EPSD	TCGA;ICGC;COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	P84103	SRSF3	P31749	AKT1	S148	R149Q	149	Missense	proximal	1	no	13.610	13.315	EPSD	TCGA;ICGC;COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	P84103	SRSF3	P31749	AKT1	S150	R155C	155	Missense	distal	5	no	10.841	10.714	EPSD	TCGA;ICGC;COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	P84103	SRSF3	P31749	AKT1	S150	R149Q	149	Missense	proximal	-1	no	10.841	10.808	EPSD	TCGA;ICGC;COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	P84103	SRSF3	P31749	AKT1	S150	R157Q	157	Missense	distal	7	no	10.841	10.785	EPSD	TCGA;ICGC	7.780	Down-regulation
AGC_Akt_AKT1_ST	P84103	SRSF3	P31749	AKT1	S152	R155C	155	Missense	distal	3	no	14.444	14.283	EPSD	TCGA;ICGC;COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	P84103	SRSF3	P31749	AKT1	S152	R149Q	149	Missense	distal	-3	no	14.444	7.233	EPSD	TCGA;ICGC;COSMIC	7.780	Loss
AGC_Akt_AKT1_ST	P84103	SRSF3	P31749	AKT1	S152	R157Q	157	Missense	distal	5	no	14.444	14.393	EPSD	TCGA;ICGC	7.780	Down-regulation
AGC_Akt_AKT1_ST	P84103	SRSF3	P31749	AKT1	S154	R155C	155	Missense	proximal	1	no	14.977	14.449	EPSD	TCGA;ICGC;COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	P84103	SRSF3	P31749	AKT1	S154	R149Q	149	Missense	distal	-5	no	14.977	10.750	EPSD	TCGA;ICGC;COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	P84103	SRSF3	P31749	AKT1	S154	R157Q	157	Missense	distal	3	no	14.977	14.921	EPSD	TCGA;ICGC	7.780	Down-regulation
AGC_Akt_AKT1_ST	P84103	SRSF3	P31749	AKT1	S156	R155C	155	Missense	proximal	-1	no	15.818	15.747	EPSD	TCGA;ICGC;COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	P84103	SRSF3	P31749	AKT1	S156	R149Q	149	Missense	distal	-7	no	15.818	15.624	EPSD	TCGA;ICGC;COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	P84103	SRSF3	P31749	AKT1	S156	R157Q	157	Missense	proximal	1	no	15.818	15.523	EPSD	TCGA;ICGC	7.780	Down-regulation
AGC_Akt_AKT1_ST	P84103	SRSF3	P31749	AKT1	S158	R155C	155	Missense	distal	-3	no	18.645	12.471	EPSD	TCGA;ICGC;COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	P84103	SRSF3	P31749	AKT1	S158	R157Q	157	Missense	proximal	-1	no	18.645	18.612	EPSD	TCGA;ICGC	7.780	Down-regulation
AGC_Akt_AKT1_ST	P84103	SRSF3	P31749	AKT1	S160	R155C	155	Missense	distal	-5	no	18.378	14.301	EPSD	TCGA;ICGC;COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	P84103	SRSF3	P31749	AKT1	S160	R157Q	157	Missense	distal	-3	no	18.378	11.167	EPSD	TCGA;ICGC	7.780	Down-regulation
AGC_Akt_AKT1_ST	Q92794	KAT6A	P31749	AKT1	T332	I327T	327	Missense	distal	-5	no	9.379	10.217	EPSD	TCGA	7.780	Up-regulation
AGC_Akt_AKT1_ST	Q92794	KAT6A	P31749	AKT1	T332	R329Q	329	Missense	distal	-3	no	9.379	2.168	EPSD	TCGA;ICGC;COSMIC	7.780	Loss
AGC_Akt_AKT1_ST	Q92794	KAT6A	P31749	AKT1	T332	R329W	329	Missense	distal	-3	no	9.379	0.439	EPSD	TCGA;ICGC;COSMIC	7.780	Loss
AGC_Akt_AKT1_ST	Q92794	KAT6A	P31749	AKT1	T332	P338L	338	Missense	distal	6	no	9.379	9.369	EPSD	TCGA;ICGC;COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	Q92794	KAT6A	P31749	AKT1	T332	T332A	332	Missense	central	0	yes	9.379	0.000	EPSD	TCGA;ICGC;COSMIC;GDSC;CCLE	7.780	Loss
AGC_Akt_AKT1_ST	Q92794	KAT6A	P31749	AKT1	T369	L370F	370	Missense	proximal	1	no	17.379	17.298	PhosphoSitePlus	TCGA;ICGC;COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	Q92794	KAT6A	P31749	AKT1	T369	G363C	363	Missense	distal	-6	no	17.379	17.312	PhosphoSitePlus	TCGA;ICGC;COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	Q92794	KAT6A	P31749	AKT1	T369	K367N	367	Missense	proximal	-2	no	17.379	16.443	PhosphoSitePlus	TCGA;ICGC;COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	Q92794	KAT6A	P31749	AKT1	T369	R366Q	366	Missense	distal	-3	no	17.379	10.168	PhosphoSitePlus	TCGA;ICGC;COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	Q92794	KAT6A	P31749	AKT1	T369	T369N	369	Missense	central	0	yes	17.379	0.000	PhosphoSitePlus	TCGA;ICGC;COSMIC	7.780	Loss
AGC_Akt_AKT1_ST	Q92794	KAT6A	P31749	AKT1	S371	L370F	370	Missense	proximal	-1	no	11.150	11.143	EPSD	TCGA;ICGC;COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	Q92794	KAT6A	P31749	AKT1	S371	K367N	367	Missense	distal	-4	no	11.150	10.510	EPSD	TCGA;ICGC;COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	Q92794	KAT6A	P31749	AKT1	S371	R366Q	366	Missense	distal	-5	no	11.150	6.922	EPSD	TCGA;ICGC;COSMIC	7.780	Loss
AGC_Akt_AKT1_ST	Q92794	KAT6A	P31749	AKT1	S371	T369N	369	Missense	proximal	-2	no	11.150	10.530	EPSD	TCGA;ICGC;COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	Q92794	KAT6A	P31749	AKT1	S399	N397S	397	Missense	proximal	-2	no	7.654	8.340	EPSD	TCGA;ICGC;COSMIC	7.780	Gain
AGC_Akt_AKT1_ST	Q92794	KAT6A	P31749	AKT1	S399	D395Y	395	Missense	distal	-4	no	7.654	8.082	EPSD	TCGA;ICGC;COSMIC	7.780	Gain
AGC_Akt_AKT1_ST	Q92794	KAT6A	P31749	AKT1	S447	W452C	452	Missense	distal	5	no	8.751	8.719	EPSD	TCGA;ICGC;COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	Q92794	KAT6A	P31749	AKT1	S448	W452C	452	Missense	distal	4	no	13.095	13.182	EPSD	TCGA;ICGC;COSMIC	7.780	Up-regulation
AGC_Akt_AKT1_ST	Q92794	KAT6A	P31749	AKT1	S941	K937N	937	Missense	distal	-4	no	11.309	10.670	EPSD	TCGA;ICGC;COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	Q92794	KAT6A	P31749	AKT1	S941	L940F	940	Missense	proximal	-1	no	11.309	11.303	EPSD	TCGA;ICGC;COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	Q92794	KAT6A	P31749	AKT1	S941	R938G	938	Missense	distal	-3	no	11.309	4.553	EPSD	TCGA;ICGC;COSMIC	7.780	Loss
AGC_Akt_AKT1_ST	Q92794	KAT6A	P31749	AKT1	S941	R948Q	948	Missense	distal	7	no	11.309	11.253	EPSD	TCGA;ICGC;COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	Q92794	KAT6A	P31749	AKT1	S941	E945K	945	Missense	distal	4	no	11.309	11.208	EPSD	TCGA;ICGC;COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	Q92794	KAT6A	P31749	AKT1	S974	R972H	972	Missense	proximal	-2	no	11.254	10.393	EPSD	TCGA;ICGC;COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	Q92794	KAT6A	P31749	AKT1	S974	R971H	971	Missense	distal	-3	no	11.254	6.555	EPSD	TCGA;ICGC;COSMIC	7.780	Loss
AGC_Akt_AKT1_ST	Q92794	KAT6A	P31749	AKT1	S987	P994L	994	Missense	distal	7	no	10.278	10.270	EPSD	TCGA;ICGC;COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	Q92794	KAT6A	P31749	AKT1	S1001	P994L	994	Missense	distal	-7	no	11.664	11.625	EPSD	TCGA;ICGC;COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	Q92794	KAT6A	P31749	AKT1	S1089	R1082G	1082	Missense	distal	-7	no	10.985	10.743	EPSD	TCGA;ICGC;COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	Q92794	KAT6A	P31749	AKT1	S1089	R1087H	1087	Missense	proximal	-2	no	10.985	10.124	EPSD	TCGA;ICGC;COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	Q92794	KAT6A	P31749	AKT1	S1090	Q1097H	1097	Missense	distal	7	no	13.066	13.050	EPSD	TCGA;ICGC;COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	Q92794	KAT6A	P31749	AKT1	S1090	R1087H	1087	Missense	distal	-3	no	13.066	8.367	EPSD	TCGA;ICGC;COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	Q92794	KAT6A	P31749	AKT1	S1136	R1129Q	1129	Missense	distal	-7	no	8.489	8.294	EPSD	TCGA;ICGC;COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	Q92794	KAT6A	P31749	AKT1	S1861	S1866C	1866	Missense	distal	5	no	10.348	10.229	EPSD	TCGA;ICGC;COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	Q92794	KAT6A	P31749	AKT1	S1861	S1856P	1856	Missense	distal	-5	no	10.348	10.808	EPSD	TCGA;ICGC;COSMIC	7.780	Up-regulation
AGC_Akt_AKT1_ST	Q92794	KAT6A	P31749	AKT1	S1861	I1855F	1855	Missense	distal	-6	no	10.348	10.393	EPSD	TCGA;ICGC;COSMIC	7.780	Up-regulation
AGC_Akt_AKT1_ST	Q92794	KAT6A	P31749	AKT1	S1861	R1858C	1858	Missense	distal	-3	no	10.348	4.174	EPSD	TCGA;ICGC;COSMIC;GDSC	7.780	Loss
AGC_Akt_AKT1_ST	Q92794	KAT6A	P31749	AKT1	S1861	A1867V	1867	Missense	distal	6	no	10.348	10.316	EPSD	TCGA;ICGC;COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	Q92794	KAT6A	P31749	AKT1	S1861	R1858H	1858	Missense	distal	-3	no	10.348	5.649	EPSD	TCGA;ICGC	7.780	Loss
AGC_Akt_AKT1_ST	Q9UKV3	ACIN1	P31749	AKT1	T9	G12E	12	Missense	distal	3	no	11.750	11.800	EPSD	TCGA;ICGC;COSMIC	7.780	Up-regulation
AGC_Akt_AKT1_ST	Q9UKV3	ACIN1	P31749	AKT1	S10	G12E	12	Missense	proximal	2	no	8.812	8.956	EPSD	TCGA;ICGC;COSMIC	7.780	Up-regulation
AGC_Akt_AKT1_ST	Q9UKV3	ACIN1	P31749	AKT1	T13	N20K	20	Missense	distal	7	no	8.479	8.514	EPSD	TCGA;ICGC;COSMIC	7.780	Up-regulation
AGC_Akt_AKT1_ST	Q9UKV3	ACIN1	P31749	AKT1	T13	G12E	12	Missense	proximal	-1	no	8.479	8.494	EPSD	TCGA;ICGC;COSMIC	7.780	Up-regulation
AGC_Akt_AKT1_ST	Q9UKV3	ACIN1	P31749	AKT1	S207	S208L	208	Missense	proximal	1	no	10.916	11.014	EPSD	TCGA;ICGC;COSMIC	7.780	Up-regulation
AGC_Akt_AKT1_ST	Q9UKV3	ACIN1	P31749	AKT1	S207	K205T	205	Missense	proximal	-2	no	10.916	10.598	EPSD	TCGA;ICGC;COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	Q9UKV3	ACIN1	P31749	AKT1	S208	S208L	208	Missense	central	0	yes	7.840	0.000	EPSD	TCGA;ICGC;COSMIC	7.780	Loss
AGC_Akt_AKT1_ST	Q9UKV3	ACIN1	P31749	AKT1	S208	K205T	205	Missense	distal	-3	no	7.840	5.339	EPSD	TCGA;ICGC;COSMIC	7.780	Loss
AGC_Akt_AKT1_ST	Q9UKV3	ACIN1	P31749	AKT1	S229	R227Q	227	Missense	proximal	-2	no	11.478	10.966	EPSD	TCGA;ICGC;COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	Q9UKV3	ACIN1	P31749	AKT1	S240	E241Q	241	Missense	proximal	1	no	9.060	9.005	EPSD	TCGA;ICGC;COSMIC;GDSC;CCLE	7.780	Down-regulation
AGC_Akt_AKT1_ST	Q9UKV3	ACIN1	P31749	AKT1	T326	E332D	332	Missense	distal	6	no	10.447	10.357	EPSD	TCGA;ICGC	7.780	Down-regulation
AGC_Akt_AKT1_ST	Q9UKV3	ACIN1	P31749	AKT1	T326	E322D	322	Missense	distal	-4	no	10.447	9.671	EPSD	TCGA;ICGC;COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	Q9UKV3	ACIN1	P31749	AKT1	T326	S328F	328	Missense	proximal	2	no	10.447	9.870	EPSD	TCGA;ICGC;COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	Q9UKV3	ACIN1	P31749	AKT1	S328	E332D	332	Missense	distal	4	no	10.539	10.685	EPSD	TCGA;ICGC	7.780	Up-regulation
AGC_Akt_AKT1_ST	Q9UKV3	ACIN1	P31749	AKT1	S328	E322D	322	Missense	distal	-6	no	10.539	10.467	EPSD	TCGA;ICGC;COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	Q9UKV3	ACIN1	P31749	AKT1	S328	S328F	328	Missense	central	0	yes	10.539	0.000	EPSD	TCGA;ICGC;COSMIC	7.780	Loss
AGC_Akt_AKT1_ST	Q9UKV3	ACIN1	P31749	AKT1	S377	R372T	372	Missense	distal	-5	no	8.358	4.628	EPSD	TCGA;ICGC;COSMIC	7.780	Loss
AGC_Akt_AKT1_ST	Q9UKV3	ACIN1	P31749	AKT1	S377	S376Y	376	Missense	proximal	-1	no	8.358	8.332	EPSD	TCGA;ICGC;COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	Q9UKV3	ACIN1	P31749	AKT1	S386	P389S	389	Missense	distal	3	no	8.920	9.002	EPSD	TCGA;ICGC;COSMIC	7.780	Up-regulation
AGC_Akt_AKT1_ST	Q9UKV3	ACIN1	P31749	AKT1	S386	S388F	388	Missense	proximal	2	no	8.920	8.343	EPSD	TCGA;ICGC;COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	Q9UKV3	ACIN1	P31749	AKT1	S388	P389S	389	Missense	proximal	1	no	10.362	10.517	EPSD	TCGA;ICGC;COSMIC	7.780	Up-regulation
AGC_Akt_AKT1_ST	Q9UKV3	ACIN1	P31749	AKT1	S388	S388F	388	Missense	central	0	yes	10.362	0.000	EPSD	TCGA;ICGC;COSMIC	7.780	Loss
AGC_Akt_AKT1_ST	Q9UKV3	ACIN1	P31749	AKT1	S400	E406Q	406	Missense	distal	6	no	8.911	8.897	EPSD	TCGA;ICGC;COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	Q9UKV3	ACIN1	P31749	AKT1	S400	K398T	398	Missense	proximal	-2	no	8.911	8.593	EPSD	TCGA;ICGC;COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	Q9UKV3	ACIN1	P31749	AKT1	S400	A403V	403	Missense	distal	3	no	8.911	8.878	EPSD	TCGA;ICGC;COSMIC;GDSC;CCLE	7.780	Down-regulation
AGC_Akt_AKT1_ST	Q9UKV3	ACIN1	P31749	AKT1	S424	S425C	425	Missense	proximal	1	no	8.061	7.677	EPSD	TCGA;ICGC;COSMIC	7.780	Loss
AGC_Akt_AKT1_ST	Q9UKV3	ACIN1	P31749	AKT1	S467	R462M	462	Missense	distal	-5	no	7.876	3.353	EPSD	TCGA;ICGC	7.780	Loss
AGC_Akt_AKT1_ST	Q9UKV3	ACIN1	P31749	AKT1	S467	T461A	461	Missense	distal	-6	no	7.876	7.790	EPSD	TCGA;ICGC	7.780	Down-regulation
AGC_Akt_AKT1_ST	Q9UKV3	ACIN1	P31749	AKT1	S583	S578C	578	Missense	distal	-5	no	12.629	13.022	EPSD	TCGA;ICGC;COSMIC	7.780	Up-regulation
AGC_Akt_AKT1_ST	Q9UKV3	ACIN1	P31749	AKT1	S583	S587C	587	Missense	distal	4	no	12.629	12.974	EPSD	TCGA;ICGC;COSMIC	7.780	Up-regulation
AGC_Akt_AKT1_ST	Q9UKV3	ACIN1	P31749	AKT1	S585	S578C	578	Missense	distal	-7	no	10.277	9.854	EPSD	TCGA;ICGC;COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	Q9UKV3	ACIN1	P31749	AKT1	S585	R592I	592	Missense	distal	7	no	10.277	10.172	EPSD	TCGA;ICGC;COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	Q9UKV3	ACIN1	P31749	AKT1	S585	S587C	587	Missense	proximal	2	no	10.277	9.453	EPSD	TCGA;ICGC;COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	Q9UKV3	ACIN1	P31749	AKT1	S585	S591L	591	Missense	distal	6	no	10.277	10.174	EPSD	TCGA;ICGC;COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	Q9UKV3	ACIN1	P31749	AKT1	S593	R592I	592	Missense	proximal	-1	no	13.530	13.470	EPSD	TCGA;ICGC;COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	Q9UKV3	ACIN1	P31749	AKT1	S593	S587C	587	Missense	distal	-6	no	13.530	13.384	EPSD	TCGA;ICGC;COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	Q9UKV3	ACIN1	P31749	AKT1	S593	S598G	598	Missense	distal	5	no	13.530	13.467	EPSD	TCGA;ICGC;COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	Q9UKV3	ACIN1	P31749	AKT1	S593	S591L	591	Missense	proximal	-2	no	13.530	12.673	EPSD	TCGA;ICGC;COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	Q9UKV3	ACIN1	P31749	AKT1	S595	R592I	592	Missense	distal	-3	no	16.348	9.267	EPSD	TCGA;ICGC;COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	Q9UKV3	ACIN1	P31749	AKT1	S595	R602L	602	Missense	distal	7	no	16.348	16.274	EPSD	TCGA;ICGC;COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	Q9UKV3	ACIN1	P31749	AKT1	S595	S598G	598	Missense	distal	3	no	16.348	16.257	EPSD	TCGA;ICGC;COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	Q9UKV3	ACIN1	P31749	AKT1	S595	S591L	591	Missense	distal	-4	no	16.348	15.224	EPSD	TCGA;ICGC;COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	Q9UKV3	ACIN1	P31749	AKT1	S599	R592I	592	Missense	distal	-7	no	9.211	8.783	EPSD	TCGA;ICGC;COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	Q9UKV3	ACIN1	P31749	AKT1	S599	R602L	602	Missense	distal	3	no	9.211	9.130	EPSD	TCGA;ICGC;COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	Q9UKV3	ACIN1	P31749	AKT1	S599	S598G	598	Missense	proximal	-1	no	9.211	9.182	EPSD	TCGA;ICGC;COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	Q9UKV3	ACIN1	P31749	AKT1	S605	R602L	602	Missense	distal	-3	no	10.344	3.351	EPSD	TCGA;ICGC;COSMIC	7.780	Loss
AGC_Akt_AKT1_ST	Q9UKV3	ACIN1	P31749	AKT1	S605	S598G	598	Missense	distal	-7	no	10.344	10.158	EPSD	TCGA;ICGC;COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	Q9UKV3	ACIN1	P31749	AKT1	S631	E636Q	636	Missense	distal	5	no	10.506	10.495	EPSD	TCGA;ICGC;COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	Q9UKV3	ACIN1	P31749	AKT1	S635	E636Q	636	Missense	proximal	1	no	13.515	13.460	EPSD	TCGA;ICGC;COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	Q9UKV3	ACIN1	P31749	AKT1	S637	E636Q	636	Missense	proximal	-1	no	9.196	9.188	EPSD	TCGA;ICGC;COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	Q9UKV3	ACIN1	P31749	AKT1	S643	E636Q	636	Missense	distal	-7	no	16.166	16.178	EPSD	TCGA;ICGC;COSMIC	7.780	Up-regulation
AGC_Akt_AKT1_ST	Q9UKV3	ACIN1	P31749	AKT1	S643	S647L	647	Missense	distal	4	no	16.166	16.355	EPSD	TCGA;ICGC;COSMIC	7.780	Up-regulation
AGC_Akt_AKT1_ST	Q9UKV3	ACIN1	P31749	AKT1	S645	S647L	647	Missense	proximal	2	no	16.880	16.335	EPSD	TCGA;ICGC;COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	Q9UKV3	ACIN1	P31749	AKT1	S645	S652G	652	Missense	distal	7	no	16.880	16.807	EPSD	TCGA;ICGC	7.780	Down-regulation
AGC_Akt_AKT1_ST	Q9UKV3	ACIN1	P31749	AKT1	S647	S647L	647	Missense	central	0	yes	16.700	0.000	EPSD	TCGA;ICGC;COSMIC	7.780	Loss
AGC_Akt_AKT1_ST	Q9UKV3	ACIN1	P31749	AKT1	S647	S652G	652	Missense	distal	5	no	16.700	16.637	EPSD	TCGA;ICGC	7.780	Down-regulation
AGC_Akt_AKT1_ST	Q9UKV3	ACIN1	P31749	AKT1	S649	S647L	647	Missense	proximal	-2	no	15.202	14.346	EPSD	TCGA;ICGC;COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	Q9UKV3	ACIN1	P31749	AKT1	S649	S652G	652	Missense	distal	3	no	15.202	15.112	EPSD	TCGA;ICGC	7.780	Down-regulation
AGC_Akt_AKT1_ST	Q9UKV3	ACIN1	P31749	AKT1	S657	S652G	652	Missense	distal	-5	no	7.423	7.829	EPSD	TCGA;ICGC	7.780	Gain
AGC_Akt_AKT1_ST	Q9UKV3	ACIN1	P31749	AKT1	S665	S661C	661	Missense	distal	-4	no	11.178	9.585	EPSD	TCGA;ICGC;COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	Q9UKV3	ACIN1	P31749	AKT1	S665	D663G	663	Missense	proximal	-2	no	11.178	11.877	EPSD	TCGA;ICGC;COSMIC	7.780	Up-regulation
AGC_Akt_AKT1_ST	Q9UKV3	ACIN1	P31749	AKT1	T699	S701L	701	Missense	proximal	2	no	12.101	11.555	EPSD	TCGA;ICGC;COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	Q9UKV3	ACIN1	P31749	AKT1	S701	S701L	701	Missense	central	0	yes	9.519	0.000	EPSD	TCGA;ICGC;COSMIC	7.780	Loss
AGC_Akt_AKT1_ST	Q9UKV3	ACIN1	P31749	AKT1	S710	S714L	714	Missense	distal	4	no	11.643	11.831	EPSD	TCGA;ICGC;COSMIC	7.780	Up-regulation
AGC_Akt_AKT1_ST	Q9UKV3	ACIN1	P31749	AKT1	S710	E716K	716	Missense	distal	6	no	11.643	11.712	EPSD	TCGA;ICGC;COSMIC	7.780	Up-regulation
AGC_Akt_AKT1_ST	Q9UKV3	ACIN1	P31749	AKT1	S710	A715S	715	Missense	distal	5	no	11.643	11.694	EPSD	TCGA;ICGC;COSMIC	7.780	Up-regulation
AGC_Akt_AKT1_ST	Q9UKV3	ACIN1	P31749	AKT1	S815	R822G	822	Missense	distal	7	no	8.218	8.137	EPSD	TCGA;COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	Q9UKV3	ACIN1	P31749	AKT1	S815	S815L	815	Missense	central	0	yes	8.218	0.000	EPSD	TCGA;COSMIC	7.780	Loss
AGC_Akt_AKT1_ST	Q9UKV3	ACIN1	P31749	AKT1	S825	V826I	826	Missense	proximal	1	no	13.846	13.599	EPSD	TCGA;COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	Q9UKV3	ACIN1	P31749	AKT1	S825	R822G	822	Missense	distal	-3	no	13.846	7.090	EPSD	TCGA;COSMIC	7.780	Loss
AGC_Akt_AKT1_ST	Q9UKV3	ACIN1	P31749	AKT1	S825	S825F	825	Missense	central	0	yes	13.846	0.000	EPSD	TCGA;COSMIC	7.780	Loss
AGC_Akt_AKT1_ST	Q9UKV3	ACIN1	P31749	AKT1	T855	R850H	850	Missense	distal	-5	no	8.452	5.357	EPSD	TCGA;COSMIC	7.780	Loss
AGC_Akt_AKT1_ST	Q9UKV3	ACIN1	P31749	AKT1	S863	S863F	863	Missense	central	0	yes	10.121	0.000	EPSD	TCGA;COSMIC	7.780	Loss
AGC_Akt_AKT1_ST	Q9UKV3	ACIN1	P31749	AKT1	S865	S863F	863	Missense	proximal	-2	no	8.657	7.790	EPSD	TCGA;COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	Q9UKV3	ACIN1	P31749	AKT1	S983	S990F	990	Missense	distal	7	no	12.353	12.279	EPSD	TCGA;COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	Q9UKV3	ACIN1	P31749	AKT1	S983	K986Q	986	Missense	distal	3	no	12.353	12.278	EPSD	TCGA;COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	Q9UKV3	ACIN1	P31749	AKT1	S983	S987A	987	Missense	distal	4	no	12.353	12.477	EPSD	TCGA;COSMIC	7.780	Up-regulation
AGC_Akt_AKT1_ST	Q9UKV3	ACIN1	P31749	AKT1	S983	R980C	980	Missense	distal	-3	no	12.353	6.180	EPSD	TCGA;COSMIC	7.780	Loss
AGC_Akt_AKT1_ST	Q9UKV3	ACIN1	P31749	AKT1	T1159	R1155W	1155	Missense	distal	-4	no	11.318	9.768	EPSD	TCGA;COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	Q9UKV3	ACIN1	P31749	AKT1	T1159	R1160L	1160	Missense	proximal	1	no	11.318	11.271	EPSD	TCGA;COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	Q9UKV3	ACIN1	P31749	AKT1	S1161	R1155W	1155	Missense	distal	-6	no	14.927	14.779	EPSD	TCGA;COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	Q9UKV3	ACIN1	P31749	AKT1	S1161	R1160L	1160	Missense	proximal	-1	no	14.927	14.888	EPSD	TCGA;COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	Q9UKV3	ACIN1	P31749	AKT1	S1161	R1167W	1167	Missense	distal	6	no	14.927	14.769	EPSD	TCGA;COSMIC;GDSC;CCLE	7.780	Down-regulation
AGC_Akt_AKT1_ST	Q9UKV3	ACIN1	P31749	AKT1	S1176	R1175L	1175	Missense	proximal	-1	no	8.383	8.344	EPSD	TCGA;COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	Q9UKV3	ACIN1	P31749	AKT1	S1176	R1175C	1175	Missense	proximal	-1	no	8.383	8.313	EPSD	TCGA;COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	Q9UKV3	ACIN1	P31749	AKT1	S1176	R1175H	1175	Missense	proximal	-1	no	8.383	8.339	EPSD	TCGA;COSMIC;CCLE	7.780	Down-regulation
AGC_Akt_AKT1_ST	Q9UKV3	ACIN1	P31749	AKT1	S1176	R1171Q	1171	Missense	distal	-5	no	8.383	4.156	EPSD	TCGA;COSMIC	7.780	Loss
AGC_Akt_AKT1_ST	Q9UKV3	ACIN1	P31749	AKT1	S1178	R1175L	1175	Missense	distal	-3	no	12.207	5.213	EPSD	TCGA;COSMIC	7.780	Loss
AGC_Akt_AKT1_ST	Q9UKV3	ACIN1	P31749	AKT1	S1178	R1184S	1184	Missense	distal	6	no	12.207	12.208	EPSD	TCGA;COSMIC	7.780	Up-regulation
AGC_Akt_AKT1_ST	Q9UKV3	ACIN1	P31749	AKT1	S1178	R1175C	1175	Missense	distal	-3	no	12.207	6.033	EPSD	TCGA;COSMIC	7.780	Loss
AGC_Akt_AKT1_ST	Q9UKV3	ACIN1	P31749	AKT1	S1178	R1184L	1184	Missense	distal	6	no	12.207	12.104	EPSD	TCGA;COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	Q9UKV3	ACIN1	P31749	AKT1	S1178	R1175H	1175	Missense	distal	-3	no	12.207	7.508	EPSD	TCGA;COSMIC;CCLE	7.780	Loss
AGC_Akt_AKT1_ST	Q9UKV3	ACIN1	P31749	AKT1	S1178	R1171Q	1171	Missense	distal	-7	no	12.207	12.012	EPSD	TCGA;COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	Q9UKV3	ACIN1	P31749	AKT1	S1180	R1175L	1175	Missense	distal	-5	no	16.215	12.089	PhosphoSitePlus	TCGA;COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	Q9UKV3	ACIN1	P31749	AKT1	S1180	R1184S	1184	Missense	distal	4	no	16.215	16.205	PhosphoSitePlus	TCGA;COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	Q9UKV3	ACIN1	P31749	AKT1	S1180	R1175C	1175	Missense	distal	-5	no	16.215	12.139	PhosphoSitePlus	TCGA;COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	Q9UKV3	ACIN1	P31749	AKT1	S1180	R1184L	1184	Missense	distal	4	no	16.215	16.393	PhosphoSitePlus	TCGA;COSMIC	7.780	Up-regulation
AGC_Akt_AKT1_ST	Q9UKV3	ACIN1	P31749	AKT1	S1180	R1175H	1175	Missense	distal	-5	no	16.215	13.120	PhosphoSitePlus	TCGA;COSMIC;CCLE	7.780	Down-regulation
AGC_Akt_AKT1_ST	Q9UKV3	ACIN1	P31749	AKT1	S1284	R1289M	1289	Missense	distal	5	no	14.748	14.684	EPSD	TCGA	7.780	Down-regulation
AGC_Akt_AKT1_ST	Q9UKV3	ACIN1	P31749	AKT1	S1325	R1326I	1326	Missense	proximal	1	no	9.002	8.609	EPSD	TCGA;COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	Q9UKV3	ACIN1	P31749	AKT1	S1325	R1330Q	1330	Missense	distal	5	no	9.002	8.951	EPSD	TCGA;COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	Q9UKV3	ACIN1	P31749	AKT1	S1325	K1322E	1322	Missense	distal	-3	no	9.002	6.951	EPSD	TCGA;COSMIC	7.780	Loss
AGC_Akt_AKT1_ST	Q9UKV3	ACIN1	P31749	AKT1	S1325	S1327R	1327	Missense	proximal	2	no	9.002	8.830	EPSD	TCGA;COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	Q9UKV3	ACIN1	P31749	AKT1	S1325	R1323H	1323	Missense	proximal	-2	no	9.002	8.141	EPSD	TCGA;COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	Q9UKV3	ACIN1	P31749	AKT1	S1325	R1323C	1323	Missense	proximal	-2	no	9.002	7.538	EPSD	TCGA;COSMIC	7.780	Loss
AGC_Akt_AKT1_ST	Q9UKV3	ACIN1	P31749	AKT1	S1325	H1324Y	1324	Missense	proximal	-1	no	9.002	9.010	EPSD	TCGA;COSMIC	7.780	Up-regulation
AGC_Akt_AKT1_ST	Q9UKV3	ACIN1	P31749	AKT1	S1327	R1326I	1326	Missense	proximal	-1	no	13.043	12.984	EPSD	TCGA;COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	Q9UKV3	ACIN1	P31749	AKT1	S1327	R1330Q	1330	Missense	distal	3	no	13.043	12.987	EPSD	TCGA;COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	Q9UKV3	ACIN1	P31749	AKT1	S1327	K1322E	1322	Missense	distal	-5	no	13.043	11.346	EPSD	TCGA;COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	Q9UKV3	ACIN1	P31749	AKT1	S1327	S1327R	1327	Missense	central	0	yes	13.043	0.000	EPSD	TCGA;COSMIC	7.780	Loss
AGC_Akt_AKT1_ST	Q9UKV3	ACIN1	P31749	AKT1	S1327	R1323H	1323	Missense	distal	-4	no	13.043	11.985	EPSD	TCGA;COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	Q9UKV3	ACIN1	P31749	AKT1	S1327	R1323C	1323	Missense	distal	-4	no	13.043	11.365	EPSD	TCGA;COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	Q9UKV3	ACIN1	P31749	AKT1	S1327	H1324Y	1324	Missense	distal	-3	no	13.043	10.153	EPSD	TCGA;COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	Q9UKV3	ACIN1	P31749	AKT1	S1329	R1326I	1326	Missense	distal	-3	no	16.581	9.500	EPSD	TCGA;COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	Q9UKV3	ACIN1	P31749	AKT1	S1329	R1330Q	1330	Missense	proximal	1	no	16.581	16.286	EPSD	TCGA;COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	Q9UKV3	ACIN1	P31749	AKT1	S1329	K1322E	1322	Missense	distal	-7	no	16.581	16.388	EPSD	TCGA;COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	Q9UKV3	ACIN1	P31749	AKT1	S1329	S1327R	1327	Missense	proximal	-2	no	16.581	16.392	EPSD	TCGA;COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	Q9UKV3	ACIN1	P31749	AKT1	S1329	R1323H	1323	Missense	distal	-6	no	16.581	16.462	EPSD	TCGA;COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	Q9UKV3	ACIN1	P31749	AKT1	S1329	R1323C	1323	Missense	distal	-6	no	16.581	16.400	EPSD	TCGA;COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	Q9UKV3	ACIN1	P31749	AKT1	S1329	H1324Y	1324	Missense	distal	-5	no	16.581	15.067	EPSD	TCGA;COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	Q9UKV3	ACIN1	P31749	AKT1	S1329	R1335Q	1335	Missense	distal	6	no	16.581	16.510	EPSD	TCGA;COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	Q9UKV3	ACIN1	P31749	AKT1	S1331	R1326I	1326	Missense	distal	-5	no	19.055	14.488	EPSD	TCGA;COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	Q9UKV3	ACIN1	P31749	AKT1	S1331	R1330Q	1330	Missense	proximal	-1	no	19.055	19.023	EPSD	TCGA;COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	Q9UKV3	ACIN1	P31749	AKT1	S1331	S1327R	1327	Missense	distal	-4	no	19.055	19.141	EPSD	TCGA;COSMIC	7.780	Up-regulation
AGC_Akt_AKT1_ST	Q9UKV3	ACIN1	P31749	AKT1	S1331	H1324Y	1324	Missense	distal	-7	no	19.055	19.094	EPSD	TCGA;COSMIC	7.780	Up-regulation
AGC_Akt_AKT1_ST	Q9UKV3	ACIN1	P31749	AKT1	S1331	R1335Q	1335	Missense	distal	4	no	19.055	19.178	EPSD	TCGA;COSMIC	7.780	Up-regulation
AGC_Akt_AKT1_ST	Q9UKV3	ACIN1	P31749	AKT1	T1332	S1327R	1327	Missense	distal	-5	no	6.794	11.264	EPSD	TCGA;COSMIC	7.780	Gain
AGC_Akt_AKT1_ST	Q07352	ZFP36L1	P31749	AKT1	S54	R51W	51	Missense	distal	-3	no	11.489	2.549	EPSD	TCGA;ICGC;COSMIC	7.780	Loss
AGC_Akt_AKT1_ST	Q07352	ZFP36L1	P31749	AKT1	S54	V55D	55	Missense	proximal	1	no	11.489	11.277	EPSD	TCGA;ICGC;COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	Q07352	ZFP36L1	P31749	AKT1	T56	R51W	51	Missense	distal	-5	no	10.539	5.019	EPSD	TCGA;ICGC;COSMIC	7.780	Loss
AGC_Akt_AKT1_ST	Q07352	ZFP36L1	P31749	AKT1	T56	V55D	55	Missense	proximal	-1	no	10.539	10.526	EPSD	TCGA;ICGC;COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	Q07352	ZFP36L1	P31749	AKT1	S90	R87G	87	Missense	distal	-3	no	14.321	7.565	EPSD	TCGA;ICGC;COSMIC	7.780	Loss
AGC_Akt_AKT1_ST	Q07352	ZFP36L1	P31749	AKT1	S90	G95V	95	Missense	distal	5	no	14.321	14.324	EPSD	TCGA;ICGC;COSMIC	7.780	Up-regulation
AGC_Akt_AKT1_ST	Q07352	ZFP36L1	P31749	AKT1	S90	R87Q	87	Missense	distal	-3	no	14.321	7.109	EPSD	TCGA;ICGC;COSMIC	7.780	Loss
AGC_Akt_AKT1_ST	Q07352	ZFP36L1	P31749	AKT1	S90	D83H	83	Missense	distal	-7	no	14.321	14.447	EPSD	TCGA;ICGC;COSMIC	7.780	Up-regulation
AGC_Akt_AKT1_ST	Q07352	ZFP36L1	P31749	AKT1	S92	R87G	87	Missense	distal	-5	no	16.289	12.225	PhosphoSitePlus;EPSD	TCGA;ICGC;COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	Q07352	ZFP36L1	P31749	AKT1	S92	G95V	95	Missense	distal	3	no	16.289	16.290	PhosphoSitePlus;EPSD	TCGA;ICGC;COSMIC	7.780	Up-regulation
AGC_Akt_AKT1_ST	Q07352	ZFP36L1	P31749	AKT1	S92	L98M	98	Missense	distal	6	no	16.289	16.294	PhosphoSitePlus;EPSD	TCGA;ICGC	7.780	Up-regulation
AGC_Akt_AKT1_ST	Q07352	ZFP36L1	P31749	AKT1	S92	R87Q	87	Missense	distal	-5	no	16.289	12.062	PhosphoSitePlus;EPSD	TCGA;ICGC;COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	Q07352	ZFP36L1	P31749	AKT1	S192	A186T	186	Missense	distal	-6	no	10.035	10.121	EPSD	TCGA;ICGC;COSMIC	7.780	Up-regulation
AGC_Akt_AKT1_ST	Q07352	ZFP36L1	P31749	AKT1	S203	S201R	201	Missense	proximal	-2	no	8.916	8.727	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	Q07352	ZFP36L1	P31749	AKT1	S283	P281L	281	Missense	proximal	-2	no	10.331	10.299	EPSD	TCGA;ICGC;COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	Q07352	ZFP36L1	P31749	AKT1	S283	M288T	288	Missense	distal	5	no	10.331	10.388	EPSD	TCGA;ICGC;COSMIC;CCLE	7.780	Up-regulation
AGC_Akt_AKT1_ST	Q07352	ZFP36L1	P31749	AKT1	S283	L278I	278	Missense	distal	-5	no	10.331	9.890	EPSD	TCGA;ICGC;COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	Q07352	ZFP36L1	P31749	AKT1	S316	S312R	312	Missense	distal	-4	no	9.838	9.924	EPSD	TCGA;ICGC;COSMIC	7.780	Up-regulation
AGC_Akt_AKT1_ST	Q07352	ZFP36L1	P31749	AKT1	S316	S318F	318	Missense	proximal	2	no	9.838	9.261	EPSD	TCGA;ICGC;COSMIC;GDSC;CCLE	7.780	Down-regulation
AGC_Akt_AKT1_ST	Q07352	ZFP36L1	P31749	AKT1	S318	S312R	312	Missense	distal	-6	no	9.296	9.331	EPSD	TCGA;ICGC;COSMIC	7.780	Up-regulation
AGC_Akt_AKT1_ST	Q07352	ZFP36L1	P31749	AKT1	S318	S318F	318	Missense	central	0	yes	9.296	0.000	EPSD	TCGA;ICGC;COSMIC;GDSC;CCLE	7.780	Loss
AGC_Akt_AKT1_ST	Q9Y3C5	RNF11	P31749	AKT1	T9	S14T	14	Missense	distal	5	no	8.105	8.106	EPSD	TCGA;ICGC;COSMIC	7.780	Up-regulation
AGC_Akt_AKT1_ST	Q9Y3C5	RNF11	P31749	AKT1	T9	S14F	14	Missense	distal	5	no	8.105	8.033	EPSD	TCGA;ICGC;COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	Q9Y3C5	RNF11	P31749	AKT1	T135	C136Y	136	Missense	proximal	1	no	11.853	12.230	PhosphoSitePlus	TCGA;ICGC;COSMIC	7.780	Up-regulation
AGC_Akt_AKT1_ST	Q9Y3C5	RNF11	P31749	AKT1	T135	T135M	135	Missense	central	0	yes	11.853	0.000	PhosphoSitePlus	TCGA;ICGC;COSMIC	7.780	Loss
AGC_Akt_AKT1_ST	Q14315	FLNC	P31749	AKT1	S339	R334H	334	Missense	distal	-5	no	8.351	5.256	EPSD	TCGA;ICGC;COSMIC	7.780	Loss
AGC_Akt_AKT1_ST	Q14315	FLNC	P31749	AKT1	S339	P342T	342	Missense	distal	3	no	8.351	8.432	EPSD	TCGA;ICGC;COSMIC	7.780	Up-regulation
AGC_Akt_AKT1_ST	Q14315	FLNC	P31749	AKT1	S339	R334C	334	Missense	distal	-5	no	8.351	4.274	EPSD	TCGA;ICGC;COSMIC	7.780	Loss
AGC_Akt_AKT1_ST	Q14315	FLNC	P31749	AKT1	S339	A337D	337	Missense	proximal	-2	no	8.351	7.410	EPSD	TCGA;ICGC;COSMIC	7.780	Loss
AGC_Akt_AKT1_ST	Q14315	FLNC	P31749	AKT1	T423	R420W	420	Missense	distal	-3	no	9.759	0.819	EPSD	TCGA;ICGC;COSMIC	7.780	Loss
AGC_Akt_AKT1_ST	Q14315	FLNC	P31749	AKT1	T423	R420Q	420	Missense	distal	-3	no	9.759	2.548	EPSD	TCGA;ICGC;COSMIC;GDSC	7.780	Loss
AGC_Akt_AKT1_ST	Q14315	FLNC	P31749	AKT1	S625	G622R	622	Missense	distal	-3	no	4.286	11.042	EPSD	TCGA;ICGC;COSMIC	7.780	Gain
AGC_Akt_AKT1_ST	Q14315	FLNC	P31749	AKT1	S729	G722D	722	Missense	distal	-7	no	8.740	8.554	EPSD	TCGA;ICGC;COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	Q14315	FLNC	P31749	AKT1	T1004	L999R	999	Missense	distal	-5	no	4.131	8.258	EPSD	TCGA;ICGC	7.780	Gain
AGC_Akt_AKT1_ST	Q14315	FLNC	P31749	AKT1	S1005	S1005L	1005	Missense	central	0	yes	10.467	0.000	EPSD	TCGA;ICGC;COSMIC;CCLE	7.780	Loss
AGC_Akt_AKT1_ST	Q14315	FLNC	P31749	AKT1	S1005	P1006T	1006	Missense	proximal	1	no	10.467	10.815	EPSD	TCGA;ICGC;COSMIC	7.780	Up-regulation
AGC_Akt_AKT1_ST	Q14315	FLNC	P31749	AKT1	S1005	R1002Q	1002	Missense	distal	-3	no	10.467	3.255	EPSD	TCGA;ICGC;COSMIC;CCLE	7.780	Loss
AGC_Akt_AKT1_ST	Q14315	FLNC	P31749	AKT1	S1005	L999R	999	Missense	distal	-6	no	10.467	10.552	EPSD	TCGA;ICGC	7.780	Up-regulation
AGC_Akt_AKT1_ST	Q14315	FLNC	P31749	AKT1	S1005	R1009W	1009	Missense	distal	4	no	10.467	10.714	EPSD	TCGA;ICGC	7.780	Up-regulation
AGC_Akt_AKT1_ST	Q14315	FLNC	P31749	AKT1	S1007	S1005L	1005	Missense	proximal	-2	no	9.815	8.958	EPSD	TCGA;ICGC;COSMIC;CCLE	7.780	Down-regulation
AGC_Akt_AKT1_ST	Q14315	FLNC	P31749	AKT1	S1007	P1006T	1006	Missense	proximal	-1	no	9.815	9.850	EPSD	TCGA;ICGC;COSMIC	7.780	Up-regulation
AGC_Akt_AKT1_ST	Q14315	FLNC	P31749	AKT1	S1007	R1002Q	1002	Missense	distal	-5	no	9.815	5.587	EPSD	TCGA;ICGC;COSMIC;CCLE	7.780	Loss
AGC_Akt_AKT1_ST	Q14315	FLNC	P31749	AKT1	S1007	R1009W	1009	Missense	proximal	2	no	9.815	9.359	EPSD	TCGA;ICGC	7.780	Down-regulation
AGC_Akt_AKT1_ST	Q14315	FLNC	P31749	AKT1	T1281	A1277V	1277	Missense	distal	-4	no	12.372	12.001	EPSD	TCGA;ICGC;COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	Q14315	FLNC	P31749	AKT1	T1281	T1283I	1283	Missense	proximal	2	no	12.372	11.791	EPSD	TCGA;ICGC;COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	Q14315	FLNC	P31749	AKT1	T1281	S1279F	1279	Missense	proximal	-2	no	12.372	11.506	EPSD	TCGA;ICGC;COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	Q14315	FLNC	P31749	AKT1	T1281	A1282T	1282	Missense	proximal	1	no	12.372	12.639	EPSD	TCGA;ICGC;COSMIC	7.780	Up-regulation
AGC_Akt_AKT1_ST	Q14315	FLNC	P31749	AKT1	T1281	G1285D	1285	Missense	distal	4	no	12.372	12.424	EPSD	TCGA;ICGC;COSMIC	7.780	Up-regulation
AGC_Akt_AKT1_ST	Q14315	FLNC	P31749	AKT1	T1281	G1284D	1284	Missense	distal	3	no	12.372	12.352	EPSD	TCGA;ICGC	7.780	Down-regulation
AGC_Akt_AKT1_ST	Q14315	FLNC	P31749	AKT1	T1799	G1796R	1796	Missense	distal	-3	no	4.686	11.442	EPSD	TCGA;ICGC;COSMIC	7.780	Gain
AGC_Akt_AKT1_ST	Q14315	FLNC	P31749	AKT1	S1985	S1985L	1985	Missense	central	0	yes	10.952	0.000	EPSD	TCGA;COSMIC;GDSC	7.780	Loss
AGC_Akt_AKT1_ST	Q14315	FLNC	P31749	AKT1	S1985	R1982C	1982	Missense	distal	-3	no	10.952	4.778	EPSD	TCGA;ICGC;COSMIC	7.780	Loss
AGC_Akt_AKT1_ST	Q14315	FLNC	P31749	AKT1	S2146	G2151S	2151	Missense	distal	5	no	7.732	7.795	EPSD	TCGA;ICGC;COSMIC;GDSC;CCLE	7.780	Gain
AGC_Akt_AKT1_ST	Q14315	FLNC	P31749	AKT1	S2146	A2148T	2148	Missense	proximal	2	no	7.732	8.033	EPSD	TCGA;ICGC;COSMIC	7.780	Gain
AGC_Akt_AKT1_ST	Q14315	FLNC	P31749	AKT1	T2179	R2176C	2176	Missense	distal	-3	no	12.798	6.625	EPSD	TCGA;ICGC;COSMIC	7.780	Loss
AGC_Akt_AKT1_ST	Q14315	FLNC	P31749	AKT1	S2181	R2176C	2176	Missense	distal	-5	no	11.571	7.494	EPSD	TCGA;ICGC;COSMIC	7.780	Loss
AGC_Akt_AKT1_ST	Q14315	FLNC	P31749	AKT1	S2181	T2188M	2188	Missense	distal	7	no	11.571	11.502	EPSD	TCGA;ICGC;COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	Q14315	FLNC	P31749	AKT1	S2233	Q2240P	2240	Missense	distal	7	no	15.302	15.292	PhosphoSitePlus	TCGA;ICGC;COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	Q14315	FLNC	P31749	AKT1	S2233	R2228W	2228	Missense	distal	-5	no	15.302	9.782	PhosphoSitePlus	TCGA;ICGC;COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	Q14315	FLNC	P31749	AKT1	S2233	R2228Q	2228	Missense	distal	-5	no	15.302	11.074	PhosphoSitePlus	TCGA;COSMIC;GDSC;CCLE	7.780	Down-regulation
AGC_Akt_AKT1_ST	Q14315	FLNC	P31749	AKT1	S2233	G2227D	2227	Missense	distal	-6	no	15.302	15.263	PhosphoSitePlus	TCGA;COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	Q14315	FLNC	P31749	AKT1	S2233	L2226P	2226	Missense	distal	-7	no	15.302	15.341	PhosphoSitePlus	TCGA;ICGC;COSMIC	7.780	Up-regulation
AGC_Akt_AKT1_ST	Q14315	FLNC	P31749	AKT1	T2412	R2409C	2409	Missense	distal	-3	no	12.147	5.973	EPSD	TCGA;COSMIC	7.780	Loss
AGC_Akt_AKT1_ST	Q14315	FLNC	P31749	AKT1	T2412	E2418K	2418	Missense	distal	6	no	12.147	12.216	EPSD	TCGA;COSMIC	7.780	Up-regulation
AGC_Akt_AKT1_ST	Q14315	FLNC	P31749	AKT1	T2412	R2410C	2410	Missense	proximal	-2	no	12.147	10.683	EPSD	TCGA;ICGC;COSMIC;GDSC;CCLE	7.780	Down-regulation
AGC_Akt_AKT1_ST	Q14315	FLNC	P31749	AKT1	T2412	E2418D	2418	Missense	distal	6	no	12.147	12.056	EPSD	TCGA	7.780	Down-regulation
AGC_Akt_AKT1_ST	Q14315	FLNC	P31749	AKT1	T2412	S2405L	2405	Missense	distal	-7	no	12.147	11.913	EPSD	TCGA;ICGC;COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	Q14315	FLNC	P31749	AKT1	T2414	R2409C	2409	Missense	distal	-5	no	9.293	5.216	EPSD	TCGA;COSMIC	7.780	Loss
AGC_Akt_AKT1_ST	Q14315	FLNC	P31749	AKT1	T2414	G2420V	2420	Missense	distal	6	no	9.293	9.284	EPSD	TCGA;ICGC	7.780	Down-regulation
AGC_Akt_AKT1_ST	Q14315	FLNC	P31749	AKT1	T2414	E2418K	2418	Missense	distal	4	no	9.293	9.192	EPSD	TCGA;COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	Q14315	FLNC	P31749	AKT1	T2414	R2410C	2410	Missense	distal	-4	no	9.293	7.614	EPSD	TCGA;ICGC;COSMIC;GDSC;CCLE	7.780	Loss
AGC_Akt_AKT1_ST	Q14315	FLNC	P31749	AKT1	T2414	E2418D	2418	Missense	distal	4	no	9.293	9.439	EPSD	TCGA	7.780	Up-regulation
AGC_Akt_AKT1_ST	Q14315	FLNC	P31749	AKT1	T2446	D2441N	2441	Missense	distal	-5	no	8.924	8.485	EPSD	TCGA;ICGC;COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	Q14315	FLNC	P31749	AKT1	T2446	S2448L	2448	Missense	proximal	2	no	8.924	8.379	EPSD	TCGA;ICGC;COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	Q14315	FLNC	P31749	AKT1	T2446	P2447R	2447	Missense	proximal	1	no	8.924	9.224	EPSD	TCGA	7.780	Up-regulation
AGC_Akt_AKT1_ST	Q14315	FLNC	P31749	AKT1	T2446	R2443Q	2443	Missense	distal	-3	no	8.924	1.713	EPSD	TCGA;COSMIC;CCLE	7.780	Loss
AGC_Akt_AKT1_ST	Q14315	FLNC	P31749	AKT1	S2448	D2441N	2441	Missense	distal	-7	no	10.470	10.728	EPSD	TCGA;ICGC;COSMIC	7.780	Up-regulation
AGC_Akt_AKT1_ST	Q14315	FLNC	P31749	AKT1	S2448	S2448L	2448	Missense	central	0	yes	10.470	0.000	EPSD	TCGA;ICGC;COSMIC	7.780	Loss
AGC_Akt_AKT1_ST	Q14315	FLNC	P31749	AKT1	S2448	P2447R	2447	Missense	proximal	-1	no	10.470	10.510	EPSD	TCGA	7.780	Up-regulation
AGC_Akt_AKT1_ST	Q14315	FLNC	P31749	AKT1	S2448	R2443Q	2443	Missense	distal	-5	no	10.470	6.243	EPSD	TCGA;COSMIC;CCLE	7.780	Loss
AGC_Akt_AKT1_ST	Q14315	FLNC	P31749	AKT1	S2624	S2626N	2626	Missense	proximal	2	no	12.121	11.852	EPSD	TCGA;COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	Q14315	FLNC	P31749	AKT1	S2626	S2626N	2626	Missense	central	0	yes	8.485	0.000	EPSD	TCGA;COSMIC	7.780	Loss
AGC_Akt_AKT1_ST	Q14315	FLNC	P31749	AKT1	S2646	R2641W	2641	Missense	distal	-5	no	8.723	3.203	EPSD	TCGA;COSMIC	7.780	Loss
AGC_Akt_AKT1_ST	Q14315	FLNC	P31749	AKT1	S2646	R2641Q	2641	Missense	distal	-5	no	8.723	4.495	EPSD	TCGA	7.780	Loss
AGC_Akt_AKT1_ST	Q14315	FLNC	P31749	AKT1	S2646	P2643T	2643	Missense	distal	-3	no	8.723	8.341	EPSD	TCGA;ICGC;COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	Q14315	FLNC	P31749	AKT1	S2646	A2648V	2648	Missense	proximal	2	no	8.723	8.560	EPSD	TCGA;COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	Q14315	FLNC	P31749	AKT1	S2646	R2641L	2641	Missense	distal	-5	no	8.723	4.596	EPSD	TCGA;COSMIC	7.780	Loss
AGC_Akt_AKT1_ST	Q15027	ACAP1	P31749	AKT1	S133	G130R	130	Missense	distal	-3	no	3.787	10.543	EPSD	TCGA;ICGC;COSMIC	7.780	Gain
AGC_Akt_AKT1_ST	Q15027	ACAP1	P31749	AKT1	S361	S358R	358	Missense	distal	-3	no	3.806	11.583	EPSD	TCGA;ICGC;COSMIC	7.780	Gain
AGC_Akt_AKT1_ST	Q15027	ACAP1	P31749	AKT1	S459	F454L	454	Missense	distal	-5	no	7.976	7.371	EPSD	TCGA;ICGC;COSMIC	7.780	Loss
AGC_Akt_AKT1_ST	Q15027	ACAP1	P31749	AKT1	S459	R458Q	458	Missense	proximal	-1	no	7.976	7.943	EPSD	TCGA;ICGC;COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	Q15027	ACAP1	P31749	AKT1	S720	D726N	726	Missense	distal	6	no	10.787	10.869	EPSD	TCGA;COSMIC	7.780	Up-regulation
AGC_Akt_AKT1_ST	Q15027	ACAP1	P31749	AKT1	S724	D726N	726	Missense	proximal	2	no	7.816	8.146	EPSD	TCGA;COSMIC	7.780	Up-regulation
AGC_Akt_AKT1_ST	Q15027	ACAP1	P31749	AKT1	S731	D726N	726	Missense	distal	-5	no	9.397	8.958	EPSD	TCGA;COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	Q15027	ACAP1	P31749	AKT1	S731	L737I	737	Missense	distal	6	no	9.397	9.336	EPSD	TCGA	7.780	Down-regulation
AGC_Akt_AKT1_ST	Q13107	USP4	P31749	AKT1	S231	Q227H	227	Missense	distal	-4	no	7.799	7.361	EPSD	TCGA;ICGC;COSMIC	7.780	Loss
AGC_Akt_AKT1_ST	Q13107	USP4	P31749	AKT1	T242	S244F	244	Missense	proximal	2	no	12.173	11.596	EPSD	TCGA;ICGC;COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	Q13107	USP4	P31749	AKT1	S244	S244F	244	Missense	central	0	yes	10.240	0.000	EPSD	TCGA;ICGC;COSMIC	7.780	Loss
AGC_Akt_AKT1_ST	Q13107	USP4	P31749	AKT1	S248	S244F	244	Missense	distal	-4	no	8.144	6.977	EPSD	TCGA;ICGC;COSMIC	7.780	Loss
AGC_Akt_AKT1_ST	Q13107	USP4	P31749	AKT1	S445	V446L	446	Missense	proximal	1	no	14.403	14.503	PhosphoSitePlus	TCGA;COSMIC	7.780	Up-regulation
AGC_Akt_AKT1_ST	Q13107	USP4	P31749	AKT1	S445	I447T	447	Missense	proximal	2	no	14.403	14.985	PhosphoSitePlus	TCGA;COSMIC	7.780	Up-regulation
AGC_Akt_AKT1_ST	Q13107	USP4	P31749	AKT1	S445	R442G	442	Missense	distal	-3	no	14.403	7.647	PhosphoSitePlus	TCGA;COSMIC	7.780	Loss
AGC_Akt_AKT1_ST	Q13107	USP4	P31749	AKT1	S445	V448M	448	Missense	distal	3	no	14.403	14.408	PhosphoSitePlus	TCGA	7.780	Up-regulation
AGC_Akt_AKT1_ST	Q13107	USP4	P31749	AKT1	S592	S598L	598	Missense	distal	6	no	9.018	8.914	EPSD	TCGA;COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	Q13107	USP4	P31749	AKT1	S592	P591Q	591	Missense	proximal	-1	no	9.018	9.025	EPSD	TCGA	7.780	Up-regulation
AGC_Akt_AKT1_ST	Q13107	USP4	P31749	AKT1	S593	S598L	598	Missense	distal	5	no	13.949	13.883	EPSD	TCGA;COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	Q13107	USP4	P31749	AKT1	S593	P591Q	591	Missense	proximal	-2	no	13.949	14.072	EPSD	TCGA	7.780	Up-regulation
AGC_Akt_AKT1_ST	Q13107	USP4	P31749	AKT1	S595	S598L	598	Missense	distal	3	no	8.917	8.820	EPSD	TCGA;COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	Q13107	USP4	P31749	AKT1	S595	P591Q	591	Missense	distal	-4	no	8.917	9.118	EPSD	TCGA	7.780	Up-regulation
AGC_Akt_AKT1_ST	Q13107	USP4	P31749	AKT1	T775	D780Y	780	Missense	distal	5	no	8.183	8.215	EPSD	TCGA;COSMIC	7.780	Up-regulation
AGC_Akt_AKT1_ST	Q13107	USP4	P31749	AKT1	T775	P768S	768	Missense	distal	-7	no	8.183	8.377	EPSD	TCGA	7.780	Up-regulation
AGC_Akt_AKT1_ST	Q13107	USP4	P31749	AKT1	S829	V822L	822	Missense	distal	-7	no	7.863	7.906	EPSD	TCGA;COSMIC	7.780	Up-regulation
AGC_Akt_AKT1_ST	P03372	ESR1	P31749	AKT1	S154	P152T	152	Missense	proximal	-2	no	11.303	12.060	EPSD	TCGA;ICGC;COSMIC	7.780	Up-regulation
AGC_Akt_AKT1_ST	P03372	ESR1	P31749	AKT1	S167	A166S	166	Missense	proximal	-1	no	16.129	16.150	PhosphoSitePlus;EPSD	TCGA;ICGC;COSMIC	7.780	Up-regulation
AGC_Akt_AKT1_ST	P03372	ESR1	P31749	AKT1	S167	K171M	171	Missense	distal	4	no	16.129	16.316	PhosphoSitePlus;EPSD	TCGA;ICGC;COSMIC	7.780	Up-regulation
AGC_Akt_AKT1_ST	P03372	ESR1	P31749	AKT1	S201	H196R	196	Missense	distal	-5	no	5.117	8.212	EPSD	TCGA;ICGC;COSMIC	7.780	Gain
AGC_Akt_AKT1_ST	P03372	ESR1	P31749	AKT1	S236	K235N	235	Missense	proximal	-1	no	13.602	13.577	EPSD	TCGA;ICGC;COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	P03372	ESR1	P31749	AKT1	S236	A239S	239	Missense	distal	3	no	13.602	13.659	EPSD	TCGA;ICGC;COSMIC	7.780	Up-regulation
AGC_Akt_AKT1_ST	P03372	ESR1	P31749	AKT1	S236	R243H	243	Missense	distal	7	no	13.602	13.530	EPSD	TCGA;ICGC;COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	P03372	ESR1	P31749	AKT1	S236	R243C	243	Missense	distal	7	no	13.602	13.472	EPSD	TCGA;ICGC;COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	P03372	ESR1	P31749	AKT1	S236	C240Y	240	Missense	distal	4	no	13.602	13.393	EPSD	TCGA;ICGC;COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	P03372	ESR1	P31749	AKT1	S305	I298M	298	Missense	distal	-7	no	12.276	12.432	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	7.780	Up-regulation
AGC_Akt_AKT1_ST	P03372	ESR1	P31749	AKT1	S305	A307S	307	Missense	proximal	2	no	12.276	12.651	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	7.780	Up-regulation
AGC_Akt_AKT1_ST	P03372	ESR1	P31749	AKT1	S305	T311M	311	Missense	distal	6	no	12.276	12.156	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	Q12778	FOXO1	P31749	AKT1	S22	S22W	22	Missense	central	0	yes	10.495	0.000	EPSD	TCGA;ICGC;COSMIC;CCLE	7.780	Loss
AGC_Akt_AKT1_ST	Q12778	FOXO1	P31749	AKT1	T24	S22W	22	Missense	proximal	-2	no	14.694	13.251	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC;CCLE	7.780	Down-regulation
AGC_Akt_AKT1_ST	Q12778	FOXO1	P31749	AKT1	S256	A255T	255	Missense	proximal	-1	no	16.241	16.267	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	7.780	Up-regulation
AGC_Akt_AKT1_ST	Q12778	FOXO1	P31749	AKT1	S256	R251S	251	Missense	distal	-5	no	16.241	11.770	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	Q12778	FOXO1	P31749	AKT1	S256	P250L	250	Missense	distal	-6	no	16.241	16.254	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	7.780	Up-regulation
AGC_Akt_AKT1_ST	Q12778	FOXO1	P31749	AKT1	S256	P250S	250	Missense	distal	-6	no	16.241	16.305	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	7.780	Up-regulation
AGC_Akt_AKT1_ST	Q12778	FOXO1	P31749	AKT1	S256	N260S	260	Missense	distal	4	no	16.241	16.131	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	Q12778	FOXO1	P31749	AKT1	S256	S249Y	249	Missense	distal	-7	no	16.241	16.034	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	Q12778	FOXO1	P31749	AKT1	S276	S279F	279	Missense	distal	3	no	8.877	8.779	EPSD	TCGA;ICGC;COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	Q12778	FOXO1	P31749	AKT1	T317	R314C	314	Missense	distal	-3	no	10.948	4.775	EPSD	TCGA;ICGC;COSMIC	7.780	Loss
AGC_Akt_AKT1_ST	Q12778	FOXO1	P31749	AKT1	T317	W310L	310	Missense	distal	-7	no	10.948	11.082	EPSD	TCGA;ICGC;COSMIC	7.780	Up-regulation
AGC_Akt_AKT1_ST	Q12778	FOXO1	P31749	AKT1	T317	R314H	314	Missense	distal	-3	no	10.948	6.250	EPSD	TCGA;ICGC;COSMIC	7.780	Loss
AGC_Akt_AKT1_ST	Q12778	FOXO1	P31749	AKT1	T317	T323A	323	Missense	distal	6	no	10.948	10.846	EPSD	TCGA;ICGC;COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	Q12778	FOXO1	P31749	AKT1	T317	F313V	313	Missense	distal	-4	no	10.948	11.022	EPSD	TCGA;ICGC	7.780	Up-regulation
AGC_Akt_AKT1_ST	Q12778	FOXO1	P31749	AKT1	T317	R316Q	316	Missense	proximal	-1	no	10.948	10.916	EPSD	TCGA;ICGC;COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	Q12778	FOXO1	P31749	AKT1	S319	R314C	314	Missense	distal	-5	no	17.079	13.002	PhosphoSitePlus;EPSD	TCGA;ICGC;COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	Q12778	FOXO1	P31749	AKT1	S319	G326R	326	Missense	distal	7	no	17.079	17.159	PhosphoSitePlus;EPSD	TCGA;ICGC;COSMIC	7.780	Up-regulation
AGC_Akt_AKT1_ST	Q12778	FOXO1	P31749	AKT1	S319	R314H	314	Missense	distal	-5	no	17.079	13.984	PhosphoSitePlus;EPSD	TCGA;ICGC;COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	Q12778	FOXO1	P31749	AKT1	S319	T323A	323	Missense	distal	4	no	17.079	17.208	PhosphoSitePlus;EPSD	TCGA;ICGC;COSMIC	7.780	Up-regulation
AGC_Akt_AKT1_ST	Q12778	FOXO1	P31749	AKT1	S319	F313V	313	Missense	distal	-6	no	17.079	17.078	PhosphoSitePlus;EPSD	TCGA;ICGC	7.780	Down-regulation
AGC_Akt_AKT1_ST	Q12778	FOXO1	P31749	AKT1	S319	R316Q	316	Missense	distal	-3	no	17.079	9.867	PhosphoSitePlus;EPSD	TCGA;ICGC;COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	Q12778	FOXO1	P31749	AKT1	S329	G326R	326	Missense	distal	-3	no	3.571	10.327	EPSD	TCGA;ICGC;COSMIC	7.780	Gain
AGC_Akt_AKT1_ST	P24941	CDK2	P31749	AKT1	T39	T39I	39	Missense	central	0	yes	11.312	0.000	PhosphoSitePlus	TCGA	7.780	Loss
AGC_Akt_AKT1_ST	P24941	CDK2	P31749	AKT1	T39	K34T	34	Missense	distal	-5	no	11.312	9.980	PhosphoSitePlus	TCGA;ICGC;COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	P24941	CDK2	P31749	AKT1	T41	T39I	39	Missense	proximal	-2	no	8.353	7.178	EPSD	TCGA	7.780	Loss
AGC_Akt_AKT1_ST	P24941	CDK2	P31749	AKT1	T41	K34T	34	Missense	distal	-7	no	8.353	8.361	EPSD	TCGA;ICGC;COSMIC	7.780	Up-regulation
AGC_Akt_AKT1_ST	P24941	CDK2	P31749	AKT1	T160	V163M	163	Missense	distal	3	no	10.875	10.880	EPSD	TCGA;ICGC;COSMIC	7.780	Up-regulation
AGC_Akt_AKT1_ST	P24941	CDK2	P31749	AKT1	T160	P155H	155	Missense	distal	-5	no	10.875	11.790	EPSD	TCGA	7.780	Up-regulation
AGC_Akt_AKT1_ST	P55316	FOXG1	P31749	AKT1	S19	S16F	16	Missense	distal	-3	no	5.740	7.922	EPSD	TCGA;ICGC;COSMIC	7.780	Gain
AGC_Akt_AKT1_ST	P55316	FOXG1	P31749	AKT1	S277	A282V	282	Missense	distal	5	no	13.906	13.897	EPSD	TCGA;ICGC;COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	P55316	FOXG1	P31749	AKT1	S277	R281P	281	Missense	distal	4	no	13.906	14.051	EPSD	TCGA;ICGC;COSMIC	7.780	Up-regulation
AGC_Akt_AKT1_ST	P55316	FOXG1	P31749	AKT1	S277	R274Q	274	Missense	distal	-3	no	13.906	6.695	EPSD	TCGA;ICGC;COSMIC	7.780	Loss
AGC_Akt_AKT1_ST	P55316	FOXG1	P31749	AKT1	S277	R275H	275	Missense	proximal	-2	no	13.906	13.045	EPSD	TCGA;ICGC;COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	P55316	FOXG1	P31749	AKT1	S277	R274W	274	Missense	distal	-3	no	13.906	4.966	EPSD	TCGA;ICGC;COSMIC	7.780	Loss
AGC_Akt_AKT1_ST	P55316	FOXG1	P31749	AKT1	S277	K283R	283	Missense	distal	6	no	13.906	13.894	EPSD	TCGA;ICGC;COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	P55316	FOXG1	P31749	AKT1	S277	T278A	278	Missense	proximal	1	no	13.906	13.639	EPSD	TCGA;ICGC;COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	P55316	FOXG1	P31749	AKT1	S277	G271D	271	Missense	distal	-6	no	13.906	13.867	EPSD	TCGA;ICGC;COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	P55316	FOXG1	P31749	AKT1	S277	T270P	270	Missense	distal	-7	no	13.906	13.662	EPSD	TCGA;ICGC;COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	P55316	FOXG1	P31749	AKT1	S277	R275C	275	Missense	proximal	-2	no	13.906	12.442	EPSD	TCGA;ICGC;COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	P55316	FOXG1	P31749	AKT1	T278	A282V	282	Missense	distal	4	no	12.506	12.562	EPSD	TCGA;ICGC;COSMIC	7.780	Up-regulation
AGC_Akt_AKT1_ST	P55316	FOXG1	P31749	AKT1	T278	R281P	281	Missense	distal	3	no	12.506	12.442	EPSD	TCGA;ICGC;COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	P55316	FOXG1	P31749	AKT1	T278	R274Q	274	Missense	distal	-4	no	12.506	11.885	EPSD	TCGA;ICGC;COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	P55316	FOXG1	P31749	AKT1	T278	R275H	275	Missense	distal	-3	no	12.506	7.808	EPSD	TCGA;ICGC;COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	P55316	FOXG1	P31749	AKT1	T278	R274W	274	Missense	distal	-4	no	12.506	10.957	EPSD	TCGA;ICGC;COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	P55316	FOXG1	P31749	AKT1	T278	K283R	283	Missense	distal	5	no	12.506	12.513	EPSD	TCGA;ICGC;COSMIC	7.780	Up-regulation
AGC_Akt_AKT1_ST	P55316	FOXG1	P31749	AKT1	T278	T278A	278	Missense	central	0	yes	12.506	0.000	EPSD	TCGA;ICGC;COSMIC	7.780	Loss
AGC_Akt_AKT1_ST	P55316	FOXG1	P31749	AKT1	T278	G271D	271	Missense	distal	-7	no	12.506	12.321	EPSD	TCGA;ICGC;COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	P55316	FOXG1	P31749	AKT1	T278	R275C	275	Missense	distal	-3	no	12.506	6.333	EPSD	TCGA;ICGC;COSMIC	7.780	Loss
AGC_Akt_AKT1_ST	P55316	FOXG1	P31749	AKT1	T279	A282V	282	Missense	distal	3	no	15.575	15.543	PhosphoSitePlus	TCGA;ICGC;COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	P55316	FOXG1	P31749	AKT1	T279	R281P	281	Missense	proximal	2	no	15.575	15.410	PhosphoSitePlus	TCGA;ICGC;COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	P55316	FOXG1	P31749	AKT1	T279	R274Q	274	Missense	distal	-5	no	15.575	11.347	PhosphoSitePlus	TCGA;ICGC;COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	P55316	FOXG1	P31749	AKT1	T279	R275H	275	Missense	distal	-4	no	15.575	14.516	PhosphoSitePlus	TCGA;ICGC;COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	P55316	FOXG1	P31749	AKT1	T279	R274W	274	Missense	distal	-5	no	15.575	10.055	PhosphoSitePlus	TCGA;ICGC;COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	P55316	FOXG1	P31749	AKT1	T279	K283R	283	Missense	distal	4	no	15.575	15.608	PhosphoSitePlus	TCGA;ICGC;COSMIC	7.780	Up-regulation
AGC_Akt_AKT1_ST	P55316	FOXG1	P31749	AKT1	T279	T278A	278	Missense	proximal	-1	no	15.575	15.548	PhosphoSitePlus	TCGA;ICGC;COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	P55316	FOXG1	P31749	AKT1	T279	R275C	275	Missense	distal	-4	no	15.575	13.896	PhosphoSitePlus	TCGA;ICGC;COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	P55316	FOXG1	P31749	AKT1	S280	A282V	282	Missense	proximal	2	no	9.778	9.616	EPSD	TCGA;ICGC;COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	P55316	FOXG1	P31749	AKT1	S280	R281P	281	Missense	proximal	1	no	9.778	9.478	EPSD	TCGA;ICGC;COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	P55316	FOXG1	P31749	AKT1	S280	R274Q	274	Missense	distal	-6	no	9.778	9.694	EPSD	TCGA;ICGC;COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	P55316	FOXG1	P31749	AKT1	S280	R275H	275	Missense	distal	-5	no	9.778	6.683	EPSD	TCGA;ICGC;COSMIC	7.780	Loss
AGC_Akt_AKT1_ST	P55316	FOXG1	P31749	AKT1	S280	R274W	274	Missense	distal	-6	no	9.778	9.631	EPSD	TCGA;ICGC;COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	P55316	FOXG1	P31749	AKT1	S280	K283R	283	Missense	distal	3	no	9.778	9.759	EPSD	TCGA;ICGC;COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	P55316	FOXG1	P31749	AKT1	S280	T278A	278	Missense	proximal	-2	no	9.778	9.393	EPSD	TCGA;ICGC;COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	P55316	FOXG1	P31749	AKT1	S280	R275C	275	Missense	distal	-5	no	9.778	5.701	EPSD	TCGA;ICGC;COSMIC	7.780	Loss
AGC_Akt_AKT1_ST	P15056	BRAF	P31749	AKT1	T244	T241M	241	Missense	distal	-3	no	8.175	7.691	EPSD	TCGA;ICGC;COSMIC	7.780	Loss
AGC_Akt_AKT1_ST	P15056	BRAF	P31749	AKT1	T244	L245F	245	Missense	proximal	1	no	8.175	8.094	EPSD	TCGA;ICGC;COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	P15056	BRAF	P31749	AKT1	T244	C251R	251	Missense	distal	7	no	8.175	8.305	EPSD	TCGA;ICGC;COSMIC	7.780	Up-regulation
AGC_Akt_AKT1_ST	P15056	BRAF	P31749	AKT1	S363	S364L	364	Missense	proximal	1	no	12.988	13.086	EPSD	TCGA;ICGC;COSMIC	7.780	Up-regulation
AGC_Akt_AKT1_ST	P15056	BRAF	P31749	AKT1	S363	P367R	367	Missense	distal	4	no	12.988	12.843	EPSD	TCGA;ICGC;COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	P15056	BRAF	P31749	AKT1	S363	P367S	367	Missense	distal	4	no	12.988	12.832	EPSD	TCGA;ICGC;COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	P15056	BRAF	P31749	AKT1	S365	S364L	364	Missense	proximal	-1	no	16.893	16.864	PhosphoSitePlus;EPSD	TCGA;ICGC;COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	P15056	BRAF	P31749	AKT1	S365	P367R	367	Missense	proximal	2	no	16.893	17.057	PhosphoSitePlus;EPSD	TCGA;ICGC;COSMIC	7.780	Up-regulation
AGC_Akt_AKT1_ST	P15056	BRAF	P31749	AKT1	S365	P367S	367	Missense	proximal	2	no	16.893	17.229	PhosphoSitePlus;EPSD	TCGA;ICGC;COSMIC	7.780	Up-regulation
AGC_Akt_AKT1_ST	P15056	BRAF	P31749	AKT1	S394	T401I	401	Missense	distal	7	no	9.120	9.013	EPSD	TCGA;ICGC;COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	P15056	BRAF	P31749	AKT1	S394	F388L	388	Missense	distal	-6	no	9.120	9.144	EPSD	TCGA;ICGC;COSMIC	7.780	Up-regulation
AGC_Akt_AKT1_ST	P15056	BRAF	P31749	AKT1	S394	G397S	397	Missense	distal	3	no	9.120	9.211	EPSD	TCGA;ICGC;COSMIC	7.780	Up-regulation
AGC_Akt_AKT1_ST	P15056	BRAF	P31749	AKT1	S394	T401A	401	Missense	distal	7	no	9.120	9.059	EPSD	TCGA;ICGC;COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	P15056	BRAF	P31749	AKT1	S394	R389C	389	Missense	distal	-5	no	9.120	5.043	EPSD	TCGA;ICGC;COSMIC	7.780	Loss
AGC_Akt_AKT1_ST	P15056	BRAF	P31749	AKT1	S429	E433K	433	Missense	distal	4	no	17.215	17.114	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	P15056	BRAF	P31749	AKT1	S430	E433K	433	Missense	distal	3	no	8.153	8.197	EPSD	TCGA;ICGC;COSMIC	7.780	Up-regulation
AGC_Akt_AKT1_ST	P15056	BRAF	P31749	AKT1	S431	E433K	433	Missense	proximal	2	no	9.847	10.052	EPSD	TCGA;ICGC;COSMIC	7.780	Up-regulation
AGC_Akt_AKT1_ST	P15056	BRAF	P31749	AKT1	T440	E433K	433	Missense	distal	-7	no	13.648	13.841	EPSD	TCGA;ICGC;COSMIC	7.780	Up-regulation
AGC_Akt_AKT1_ST	P15056	BRAF	P31749	AKT1	S446	E451G	451	Missense	distal	5	no	11.248	11.218	EPSD	TCGA;ICGC;COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	P15056	BRAF	P31749	AKT1	S446	D449N	449	Missense	distal	3	no	11.248	11.304	EPSD	TCGA;ICGC;COSMIC	7.780	Up-regulation
AGC_Akt_AKT1_ST	P15056	BRAF	P31749	AKT1	S447	E451G	451	Missense	distal	4	no	9.898	9.993	EPSD	TCGA;ICGC;COSMIC	7.780	Up-regulation
AGC_Akt_AKT1_ST	P15056	BRAF	P31749	AKT1	S447	D449N	449	Missense	proximal	2	no	9.898	10.228	EPSD	TCGA;ICGC;COSMIC	7.780	Up-regulation
AGC_Akt_AKT1_ST	P15056	BRAF	P31749	AKT1	S465	G469A	469	Missense	distal	4	no	11.227	11.177	EPSD	TCGA;ICGC;COSMIC;GDSC;CCLE	7.780	Down-regulation
AGC_Akt_AKT1_ST	P15056	BRAF	P31749	AKT1	S465	G466V	466	Missense	proximal	1	no	11.227	11.530	EPSD	TCGA;ICGC;COSMIC;GDSC;CCLE	7.780	Up-regulation
AGC_Akt_AKT1_ST	P15056	BRAF	P31749	AKT1	S465	G466E	466	Missense	proximal	1	no	11.227	11.436	EPSD	TCGA;ICGC;COSMIC	7.780	Up-regulation
AGC_Akt_AKT1_ST	P15056	BRAF	P31749	AKT1	S465	G469V	469	Missense	distal	4	no	11.227	11.233	EPSD	TCGA;ICGC;COSMIC;GDSC;CCLE	7.780	Up-regulation
AGC_Akt_AKT1_ST	P15056	BRAF	P31749	AKT1	S465	G466A	466	Missense	proximal	1	no	11.227	11.458	EPSD	TCGA;ICGC;COSMIC	7.780	Up-regulation
AGC_Akt_AKT1_ST	P15056	BRAF	P31749	AKT1	S465	G464V	464	Missense	proximal	-1	no	11.227	11.221	EPSD	TCGA;ICGC;COSMIC;GDSC;CCLE	7.780	Down-regulation
AGC_Akt_AKT1_ST	P15056	BRAF	P31749	AKT1	S465	G469R	469	Missense	distal	4	no	11.227	11.064	EPSD	TCGA;ICGC;COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	P15056	BRAF	P31749	AKT1	S465	R462T	462	Missense	distal	-3	no	11.227	4.205	EPSD	TCGA;ICGC;COSMIC	7.780	Loss
AGC_Akt_AKT1_ST	P15056	BRAF	P31749	AKT1	S465	F468C	468	Missense	distal	3	no	11.227	11.148	EPSD	TCGA;ICGC;COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	P15056	BRAF	P31749	AKT1	S465	S467L	467	Missense	proximal	2	no	11.227	10.681	EPSD	TCGA;ICGC;COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	P15056	BRAF	P31749	AKT1	S465	G469E	469	Missense	distal	4	no	11.227	11.131	EPSD	TCGA;ICGC;COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	P15056	BRAF	P31749	AKT1	S465	V471I	471	Missense	distal	6	no	11.227	11.176	EPSD	TCGA;ICGC;COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	P15056	BRAF	P31749	AKT1	S465	G464E	464	Missense	proximal	-1	no	11.227	11.242	EPSD	TCGA;ICGC;COSMIC;GDSC;CCLE	7.780	Up-regulation
AGC_Akt_AKT1_ST	P15056	BRAF	P31749	AKT1	S467	G469A	469	Missense	proximal	2	no	9.345	9.301	EPSD	TCGA;ICGC;COSMIC;GDSC;CCLE	7.780	Down-regulation
AGC_Akt_AKT1_ST	P15056	BRAF	P31749	AKT1	S467	G466V	466	Missense	proximal	-1	no	9.345	9.339	EPSD	TCGA;ICGC;COSMIC;GDSC;CCLE	7.780	Down-regulation
AGC_Akt_AKT1_ST	P15056	BRAF	P31749	AKT1	S467	G466E	466	Missense	proximal	-1	no	9.345	9.360	EPSD	TCGA;ICGC;COSMIC	7.780	Up-regulation
AGC_Akt_AKT1_ST	P15056	BRAF	P31749	AKT1	S467	G469V	469	Missense	proximal	2	no	9.345	9.139	EPSD	TCGA;ICGC;COSMIC;GDSC;CCLE	7.780	Down-regulation
AGC_Akt_AKT1_ST	P15056	BRAF	P31749	AKT1	S467	G466A	466	Missense	proximal	-1	no	9.345	9.354	EPSD	TCGA;ICGC;COSMIC	7.780	Up-regulation
AGC_Akt_AKT1_ST	P15056	BRAF	P31749	AKT1	S467	G464V	464	Missense	distal	-3	no	9.345	9.236	EPSD	TCGA;ICGC;COSMIC;GDSC;CCLE	7.780	Down-regulation
AGC_Akt_AKT1_ST	P15056	BRAF	P31749	AKT1	S467	G469R	469	Missense	proximal	2	no	9.345	9.505	EPSD	TCGA;ICGC;COSMIC	7.780	Up-regulation
AGC_Akt_AKT1_ST	P15056	BRAF	P31749	AKT1	S467	R462T	462	Missense	distal	-5	no	9.345	5.615	EPSD	TCGA;ICGC;COSMIC	7.780	Loss
AGC_Akt_AKT1_ST	P15056	BRAF	P31749	AKT1	S467	F468C	468	Missense	proximal	1	no	9.345	8.944	EPSD	TCGA;ICGC;COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	P15056	BRAF	P31749	AKT1	S467	S467L	467	Missense	central	0	yes	9.345	0.000	EPSD	TCGA;ICGC;COSMIC	7.780	Loss
AGC_Akt_AKT1_ST	P15056	BRAF	P31749	AKT1	S467	G469E	469	Missense	proximal	2	no	9.345	9.488	EPSD	TCGA;ICGC;COSMIC	7.780	Up-regulation
AGC_Akt_AKT1_ST	P15056	BRAF	P31749	AKT1	S467	V471I	471	Missense	distal	4	no	9.345	9.426	EPSD	TCGA;ICGC;COSMIC	7.780	Up-regulation
AGC_Akt_AKT1_ST	P15056	BRAF	P31749	AKT1	S467	G464E	464	Missense	distal	-3	no	9.345	9.529	EPSD	TCGA;ICGC;COSMIC;GDSC;CCLE	7.780	Up-regulation
AGC_Akt_AKT1_ST	P15056	BRAF	P31749	AKT1	T599	G596R	596	Missense	distal	-3	no	3.412	10.168	EPSD	TCGA;ICGC;COSMIC;GDSC;CCLE	7.780	Gain
AGC_Akt_AKT1_ST	P15056	BRAF	P31749	AKT1	S729	L733F	733	Missense	distal	4	no	11.274	11.282	EPSD	TCGA;ICGC;COSMIC	7.780	Up-regulation
AGC_Akt_AKT1_ST	P15056	BRAF	P31749	AKT1	S729	H725Y	725	Missense	distal	-4	no	11.274	11.388	EPSD	TCGA;ICGC;COSMIC	7.780	Up-regulation
AGC_Akt_AKT1_ST	P15056	BRAF	P31749	AKT1	S729	R726C	726	Missense	distal	-3	no	11.274	5.100	EPSD	TCGA;ICGC;COSMIC;GDSC;CCLE	7.780	Loss
AGC_Akt_AKT1_ST	P15056	BRAF	P31749	AKT1	S729	P731S	731	Missense	proximal	2	no	11.274	11.610	EPSD	TCGA;ICGC;COSMIC	7.780	Up-regulation
AGC_Akt_AKT1_ST	P15056	BRAF	P31749	AKT1	S729	R735W	735	Missense	distal	6	no	11.274	11.116	EPSD	TCGA;ICGC;COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	P15056	BRAF	P31749	AKT1	S729	N734S	734	Missense	distal	5	no	11.274	11.308	EPSD	TCGA;ICGC;COSMIC	7.780	Up-regulation
AGC_Akt_AKT1_ST	P15056	BRAF	P31749	AKT1	T740	L733F	733	Missense	distal	-7	no	8.293	8.249	EPSD	TCGA;ICGC;COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	P15056	BRAF	P31749	AKT1	T740	E741D	741	Missense	proximal	1	no	8.293	8.176	EPSD	TCGA;ICGC;COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	P15056	BRAF	P31749	AKT1	T740	A747D	747	Missense	distal	7	no	8.293	8.267	EPSD	TCGA;ICGC;COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	P15056	BRAF	P31749	AKT1	T740	R735W	735	Missense	distal	-5	no	8.293	2.773	EPSD	TCGA;ICGC;COSMIC	7.780	Loss
AGC_Akt_AKT1_ST	P15056	BRAF	P31749	AKT1	T740	N734S	734	Missense	distal	-6	no	8.293	8.340	EPSD	TCGA;ICGC;COSMIC	7.780	Up-regulation
AGC_Akt_AKT1_ST	Q9Y2V2	CARHSP1	P31749	AKT1	S30	R25W	25	Missense	distal	-5	no	15.777	10.257	EPSD	TCGA;ICGC;COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	Q9Y2V2	CARHSP1	P31749	AKT1	S30	R27C	27	Missense	distal	-3	no	15.777	9.603	EPSD	TCGA;ICGC;COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	Q9Y2V2	CARHSP1	P31749	AKT1	S30	G36S	36	Missense	distal	6	no	15.777	15.882	EPSD	TCGA;ICGC;COSMIC	7.780	Up-regulation
AGC_Akt_AKT1_ST	Q9Y2V2	CARHSP1	P31749	AKT1	S30	R29H	29	Missense	proximal	-1	no	15.777	15.732	EPSD	TCGA;ICGC	7.780	Down-regulation
AGC_Akt_AKT1_ST	Q9Y2V2	CARHSP1	P31749	AKT1	S32	R25W	25	Missense	distal	-7	no	15.393	14.969	EPSD	TCGA;ICGC;COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	Q9Y2V2	CARHSP1	P31749	AKT1	S32	R27C	27	Missense	distal	-5	no	15.393	11.316	EPSD	TCGA;ICGC;COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	Q9Y2V2	CARHSP1	P31749	AKT1	S32	G36S	36	Missense	distal	4	no	15.393	15.219	EPSD	TCGA;ICGC;COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	Q9Y2V2	CARHSP1	P31749	AKT1	S32	R29H	29	Missense	distal	-3	no	15.393	10.694	EPSD	TCGA;ICGC	7.780	Down-regulation
AGC_Akt_AKT1_ST	Q9Y2V2	CARHSP1	P31749	AKT1	T50	R56W	56	Missense	distal	6	no	13.027	12.869	EPSD	TCGA;ICGC;COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	Q9Y2V2	CARHSP1	P31749	AKT1	T50	T48M	48	Missense	proximal	-2	no	13.027	12.254	EPSD	TCGA;ICGC;COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	Q9Y2V2	CARHSP1	P31749	AKT1	T50	P44L	44	Missense	distal	-6	no	13.027	13.041	EPSD	TCGA;ICGC;COSMIC	7.780	Up-regulation
AGC_Akt_AKT1_ST	Q9Y2V2	CARHSP1	P31749	AKT1	S52	R56W	56	Missense	distal	4	no	17.128	17.375	PhosphoSitePlus	TCGA;ICGC;COSMIC	7.780	Up-regulation
AGC_Akt_AKT1_ST	Q9Y2V2	CARHSP1	P31749	AKT1	S52	T48M	48	Missense	distal	-4	no	17.128	16.163	PhosphoSitePlus	TCGA;ICGC;COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	Q9Y2V2	CARHSP1	P31749	AKT1	T54	R56W	56	Missense	proximal	2	no	12.372	11.917	EPSD	TCGA;ICGC;COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	Q9Y2V2	CARHSP1	P31749	AKT1	T54	T48M	48	Missense	distal	-6	no	12.372	12.279	EPSD	TCGA;ICGC;COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	Q9Y2V2	CARHSP1	P31749	AKT1	T54	P61S	61	Missense	distal	7	no	12.372	12.430	EPSD	TCGA;ICGC;COSMIC	7.780	Up-regulation
AGC_Akt_AKT1_ST	Q9Y2V2	CARHSP1	P31749	AKT1	T139	G134R	134	Missense	distal	-5	no	8.510	12.574	EPSD	TCGA;ICGC;COSMIC	7.780	Up-regulation
AGC_Akt_AKT1_ST	Q9Y2V2	CARHSP1	P31749	AKT1	S141	G134R	134	Missense	distal	-7	no	8.201	8.443	EPSD	TCGA;ICGC;COSMIC	7.780	Up-regulation
AGC_Akt_AKT1_ST	O14745	SLC9A3R1	P31749	AKT1	S247	C242R	242	Missense	distal	-5	no	4.696	8.773	EPSD	TCGA;ICGC	7.780	Gain
AGC_Akt_AKT1_ST	O14745	SLC9A3R1	P31749	AKT1	S290	P283T	283	Missense	distal	-7	no	11.028	11.272	EPSD	TCGA;ICGC;COSMIC	7.780	Up-regulation
AGC_Akt_AKT1_ST	O14745	SLC9A3R1	P31749	AKT1	S290	T293I	293	Missense	distal	3	no	11.028	10.898	EPSD	TCGA;ICGC	7.780	Down-regulation
AGC_Akt_AKT1_ST	O14745	SLC9A3R1	P31749	AKT1	S340	R342Q	342	Missense	proximal	2	no	10.058	9.940	EPSD	TCGA;ICGC;COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	O14745	SLC9A3R1	P31749	AKT1	S340	P344S	344	Missense	distal	4	no	10.058	9.902	EPSD	TCGA;ICGC;COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	P53365	ARFIP2	P31749	AKT1	S72	G79D	79	Missense	distal	7	no	12.451	12.447	EPSD	TCGA;COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	P53365	ARFIP2	P31749	AKT1	S72	H73Y	73	Missense	proximal	1	no	12.451	12.621	EPSD	TCGA;COSMIC	7.780	Up-regulation
AGC_Akt_AKT1_ST	P53365	ARFIP2	P31749	AKT1	S74	G79D	79	Missense	distal	5	no	9.738	9.726	EPSD	TCGA;COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	P53365	ARFIP2	P31749	AKT1	S74	H73Y	73	Missense	proximal	-1	no	9.738	9.746	EPSD	TCGA;COSMIC	7.780	Up-regulation
AGC_Akt_AKT1_ST	P53365	ARFIP2	P31749	AKT1	S78	G79D	79	Missense	proximal	1	no	7.724	7.816	EPSD	TCGA;COSMIC	7.780	Gain
AGC_Akt_AKT1_ST	P53365	ARFIP2	P31749	AKT1	S260	Q262H	262	Missense	proximal	2	no	14.754	14.510	PhosphoSitePlus	TCGA;COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	P53365	ARFIP2	P31749	AKT1	S260	R255H	255	Missense	distal	-5	no	14.754	11.659	PhosphoSitePlus	TCGA	7.780	Down-regulation
AGC_Akt_AKT1_ST	Q9P0N9	TBC1D7	P31749	AKT1	S124	R121Q	121	Missense	distal	-3	no	12.487	5.276	PhosphoSitePlus	TCGA;ICGC;COSMIC	7.780	Loss
AGC_Akt_AKT1_ST	Q9P0N9	TBC1D7	P31749	AKT1	S124	R121L	121	Missense	distal	-3	no	12.487	5.494	PhosphoSitePlus	TCGA;ICGC;COSMIC	7.780	Loss
AGC_Akt_AKT1_ST	Q05195	MXD1	P31749	AKT1	T94	T94M	94	Missense	central	0	yes	11.703	0.000	EPSD	TCGA;COSMIC	7.780	Loss
AGC_Akt_AKT1_ST	Q05195	MXD1	P31749	AKT1	S96	T94M	94	Missense	proximal	-2	no	9.660	8.887	EPSD	TCGA;COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	Q05195	MXD1	P31749	AKT1	S145	I138T	138	Missense	distal	-7	no	14.110	14.532	PhosphoSitePlus	TCGA;COSMIC	7.780	Up-regulation
AGC_Akt_AKT1_ST	Q05195	MXD1	P31749	AKT1	S145	M143I	143	Missense	proximal	-2	no	14.110	13.709	PhosphoSitePlus	TCGA;COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	Q05195	MXD1	P31749	AKT1	S194	L195F	195	Missense	proximal	1	no	8.343	8.262	EPSD	TCGA;COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	P62753	RPS6	P31749	AKT1	T34	A33T	33	Missense	proximal	-1	no	11.725	11.751	EPSD	TCGA;ICGC;COSMIC	7.780	Up-regulation
AGC_Akt_AKT1_ST	P62753	RPS6	P31749	AKT1	T34	D39G	39	Missense	distal	5	no	11.725	11.736	EPSD	TCGA;ICGC;COSMIC	7.780	Up-regulation
AGC_Akt_AKT1_ST	P62753	RPS6	P31749	AKT1	T181	R178H	178	Missense	distal	-3	no	9.580	4.881	EPSD	TCGA	7.780	Loss
AGC_Akt_AKT1_ST	P62753	RPS6	P31749	AKT1	T181	R183C	183	Missense	proximal	2	no	9.580	8.927	EPSD	TCGA;ICGC;COSMIC;GDSC;CCLE	7.780	Down-regulation
AGC_Akt_AKT1_ST	P62753	RPS6	P31749	AKT1	S235	K230N	230	Missense	distal	-5	no	16.340	14.253	EPSD	TCGA;ICGC;COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	P62753	RPS6	P31749	AKT1	S235	S236C	236	Missense	proximal	1	no	16.340	15.957	EPSD	TCGA;ICGC;COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	P62753	RPS6	P31749	AKT1	S235	R232H	232	Missense	distal	-3	no	16.340	11.641	EPSD	TCGA;ICGC;COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	P62753	RPS6	P31749	AKT1	S235	R233I	233	Missense	proximal	-2	no	16.340	15.288	EPSD	TCGA;ICGC;COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	P62753	RPS6	P31749	AKT1	S235	R232C	232	Missense	distal	-3	no	16.340	10.167	EPSD	TCGA;ICGC;COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	P62753	RPS6	P31749	AKT1	S236	K230N	230	Missense	distal	-6	no	18.528	18.461	PhosphoSitePlus	TCGA;ICGC;COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	P62753	RPS6	P31749	AKT1	S236	S236C	236	Missense	central	0	yes	18.528	0.000	PhosphoSitePlus	TCGA;ICGC;COSMIC	7.780	Loss
AGC_Akt_AKT1_ST	P62753	RPS6	P31749	AKT1	S236	R232H	232	Missense	distal	-4	no	18.528	17.470	PhosphoSitePlus	TCGA;ICGC;COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	P62753	RPS6	P31749	AKT1	S236	R233I	233	Missense	distal	-3	no	18.528	11.448	PhosphoSitePlus	TCGA;ICGC;COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	P62753	RPS6	P31749	AKT1	S236	R232C	232	Missense	distal	-4	no	18.528	16.850	PhosphoSitePlus	TCGA;ICGC;COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	P62753	RPS6	P31749	AKT1	S240	S236C	236	Missense	distal	-4	no	8.495	6.902	EPSD	TCGA;ICGC;COSMIC	7.780	Loss
AGC_Akt_AKT1_ST	P62753	RPS6	P31749	AKT1	S240	R233I	233	Missense	distal	-7	no	8.495	8.067	EPSD	TCGA;ICGC;COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	P62753	RPS6	P31749	AKT1	T241	S236C	236	Missense	distal	-5	no	12.988	13.382	EPSD	TCGA;ICGC;COSMIC	7.780	Up-regulation
AGC_Akt_AKT1_ST	P62753	RPS6	P31749	AKT1	T241	Q248H	248	Missense	distal	7	no	12.988	12.973	EPSD	TCGA;ICGC;COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	P62753	RPS6	P31749	AKT1	S242	S236C	236	Missense	distal	-6	no	7.853	7.707	EPSD	TCGA;ICGC;COSMIC	7.780	Loss
AGC_Akt_AKT1_ST	P62753	RPS6	P31749	AKT1	S242	Q248H	248	Missense	distal	6	no	7.853	7.805	EPSD	TCGA;ICGC;COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	P62753	RPS6	P31749	AKT1	S246	Q248H	248	Missense	proximal	2	no	11.038	10.794	EPSD	TCGA;ICGC;COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	Q14457	BECN1	P31749	AKT1	S10	S4T	4	Missense	distal	-6	no	8.163	8.194	EPSD	TCGA;ICGC;COSMIC	7.780	Up-regulation
AGC_Akt_AKT1_ST	Q14457	BECN1	P31749	AKT1	S10	F16L	16	Missense	distal	6	no	8.163	8.179	EPSD	TCGA;ICGC;COSMIC	7.780	Up-regulation
AGC_Akt_AKT1_ST	Q14457	BECN1	P31749	AKT1	S90	P84L	84	Missense	distal	-6	no	10.581	10.595	EPSD	TCGA;ICGC;COSMIC	7.780	Up-regulation
AGC_Akt_AKT1_ST	Q14457	BECN1	P31749	AKT1	T119	R114Q	114	Missense	distal	-5	no	9.392	5.164	EPSD	TCGA;ICGC;COSMIC	7.780	Loss
AGC_Akt_AKT1_ST	Q14457	BECN1	P31749	AKT1	T119	L122F	122	Missense	distal	3	no	9.392	9.391	EPSD	TCGA;ICGC;COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	Q14457	BECN1	P31749	AKT1	T119	G120W	120	Missense	proximal	1	no	9.392	9.549	EPSD	TCGA;ICGC;COSMIC	7.780	Up-regulation
AGC_Akt_AKT1_ST	Q14457	BECN1	P31749	AKT1	S295	R292H	292	Missense	distal	-3	no	11.785	7.086	PhosphoSitePlus	TCGA;ICGC	7.780	Loss
AGC_Akt_AKT1_ST	Q9Y5S9	RBM8A	P31749	AKT1	S56	D60H	60	Missense	distal	4	no	8.991	8.962	EPSD	TCGA;ICGC;COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	Q9Y5S9	RBM8A	P31749	AKT1	S56	E52G	52	Missense	distal	-4	no	8.991	8.774	EPSD	TCGA;ICGC;COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	Q9Y5S9	RBM8A	P31749	AKT1	S166	R172T	172	Missense	distal	6	no	15.380	15.402	EPSD	TCGA;ICGC;COSMIC	7.780	Up-regulation
AGC_Akt_AKT1_ST	Q9Y5S9	RBM8A	P31749	AKT1	S166	R163Q	163	Missense	distal	-3	no	15.380	8.169	EPSD	TCGA;ICGC;COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	Q9Y5S9	RBM8A	P31749	AKT1	S166	R164I	164	Missense	proximal	-2	no	15.380	14.328	EPSD	TCGA;ICGC;COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	Q9Y5S9	RBM8A	P31749	AKT1	S166	R173L	173	Missense	distal	7	no	15.380	15.306	EPSD	TCGA;ICGC;COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	Q9Y5S9	RBM8A	P31749	AKT1	S166	R173H	173	Missense	distal	7	no	15.380	15.309	EPSD	TCGA;ICGC;COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	Q9Y5S9	RBM8A	P31749	AKT1	S166	R160I	160	Missense	distal	-6	no	15.380	15.226	EPSD	TCGA;ICGC;COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	Q9Y5S9	RBM8A	P31749	AKT1	S168	R172T	172	Missense	distal	4	no	18.571	18.555	PhosphoSitePlus	TCGA;ICGC;COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	Q9Y5S9	RBM8A	P31749	AKT1	S168	R163Q	163	Missense	distal	-5	no	18.571	14.343	PhosphoSitePlus	TCGA;ICGC;COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	Q9Y5S9	RBM8A	P31749	AKT1	S168	R164I	164	Missense	distal	-4	no	18.571	17.103	PhosphoSitePlus	TCGA;ICGC;COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	Q9Y5S9	RBM8A	P31749	AKT1	S168	R173L	173	Missense	distal	5	no	18.571	18.497	PhosphoSitePlus	TCGA;ICGC;COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	Q9Y5S9	RBM8A	P31749	AKT1	S168	R173H	173	Missense	distal	5	no	18.571	18.497	PhosphoSitePlus	TCGA;ICGC;COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	P67809	YBX1	P31749	AKT1	S102	R101C	101	Missense	proximal	-1	no	8.722	8.652	PhosphoSitePlus	TCGA;ICGC;COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	P67809	YBX1	P31749	AKT1	S102	R97M	97	Missense	distal	-5	no	8.722	4.200	PhosphoSitePlus	TCGA;ICGC;COSMIC	7.780	Loss
AGC_Akt_AKT1_ST	P67809	YBX1	P31749	AKT1	S209	R204H	204	Missense	distal	-5	no	9.316	6.221	EPSD	TCGA;ICGC;COSMIC	7.780	Loss
AGC_Akt_AKT1_ST	P67809	YBX1	P31749	AKT1	S209	R204C	204	Missense	distal	-5	no	9.316	5.239	EPSD	TCGA;ICGC	7.780	Loss
AGC_Akt_AKT1_ST	O14757	CHEK1	P31749	AKT1	S280	G281D	281	Missense	proximal	1	no	12.979	13.071	PhosphoSitePlus	TCGA;ICGC;COSMIC	7.780	Up-regulation
AGC_Akt_AKT1_ST	O14757	CHEK1	P31749	AKT1	S280	T279I	279	Missense	proximal	-1	no	12.979	12.923	PhosphoSitePlus	TCGA;ICGC;COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	O14757	CHEK1	P31749	AKT1	S280	S284L	284	Missense	distal	4	no	12.979	13.167	PhosphoSitePlus	TCGA;ICGC;COSMIC	7.780	Up-regulation
AGC_Akt_AKT1_ST	O14757	CHEK1	P31749	AKT1	S291	S288R	288	Missense	distal	-3	no	2.604	10.380	EPSD	TCGA;ICGC;COSMIC	7.780	Gain
AGC_Akt_AKT1_ST	O14757	CHEK1	P31749	AKT1	T382	R379Q	379	Missense	distal	-3	no	10.085	2.874	EPSD	TCGA;ICGC;COSMIC	7.780	Loss
AGC_Akt_AKT1_ST	Q13131	PRKAA1	P31749	AKT1	S5	R2H	2	Missense	distal	-3	no	12.347	7.648	EPSD	TCGA;ICGC;COSMIC	7.780	Loss
AGC_Akt_AKT1_ST	Q13131	PRKAA1	P31749	AKT1	S6	R2H	2	Missense	distal	-4	no	13.273	12.214	EPSD	TCGA;ICGC;COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	Q13131	PRKAA1	P31749	AKT1	S65	S65N	65	Missense	central	0	yes	11.607	0.000	EPSD	TCGA;ICGC;COSMIC	7.780	Loss
AGC_Akt_AKT1_ST	Q13131	PRKAA1	P31749	AKT1	S65	R60Q	60	Missense	distal	-5	no	11.607	7.380	EPSD	TCGA;ICGC;COSMIC;GDSC;CCLE	7.780	Loss
AGC_Akt_AKT1_ST	Q13131	PRKAA1	P31749	AKT1	S65	G70E	70	Missense	distal	5	no	11.607	11.638	EPSD	TCGA;ICGC;COSMIC	7.780	Up-regulation
AGC_Akt_AKT1_ST	Q9UQC2	GAB2	P31749	AKT1	S159	R156C	156	Missense	distal	-3	no	15.575	9.401	PhosphoSitePlus	TCGA;COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	Q9UQC2	GAB2	P31749	AKT1	T259	T265N	265	Missense	distal	6	no	10.546	10.458	EPSD	TCGA;COSMIC;CCLE	7.780	Down-regulation
AGC_Akt_AKT1_ST	Q9UQC2	GAB2	P31749	AKT1	T259	T265I	265	Missense	distal	6	no	10.546	10.361	EPSD	TCGA;COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	Q9UQC2	GAB2	P31749	AKT1	T259	F261S	261	Missense	proximal	2	no	10.546	11.124	EPSD	TCGA	7.780	Up-regulation
AGC_Akt_AKT1_ST	Q9UQC2	GAB2	P31749	AKT1	S264	R270H	270	Missense	distal	6	no	8.031	7.912	EPSD	TCGA;COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	Q9UQC2	GAB2	P31749	AKT1	S264	T265N	265	Missense	proximal	1	no	8.031	7.750	EPSD	TCGA;COSMIC;CCLE	7.780	Loss
AGC_Akt_AKT1_ST	Q9UQC2	GAB2	P31749	AKT1	S264	T265I	265	Missense	proximal	1	no	8.031	7.590	EPSD	TCGA;COSMIC	7.780	Loss
AGC_Akt_AKT1_ST	Q9UQC2	GAB2	P31749	AKT1	S264	F261S	261	Missense	distal	-3	no	8.031	5.849	EPSD	TCGA	7.780	Loss
AGC_Akt_AKT1_ST	Q9UQC2	GAB2	P31749	AKT1	T265	R270H	270	Missense	distal	5	no	7.788	7.714	EPSD	TCGA;COSMIC	7.780	Loss
AGC_Akt_AKT1_ST	Q9UQC2	GAB2	P31749	AKT1	T265	T265N	265	Missense	central	0	yes	7.788	0.000	EPSD	TCGA;COSMIC;CCLE	7.780	Loss
AGC_Akt_AKT1_ST	Q9UQC2	GAB2	P31749	AKT1	T265	T265I	265	Missense	central	0	yes	7.788	0.000	EPSD	TCGA;COSMIC	7.780	Loss
AGC_Akt_AKT1_ST	Q9UQC2	GAB2	P31749	AKT1	T265	F261S	261	Missense	distal	-4	no	7.788	8.955	EPSD	TCGA	7.780	Up-regulation
AGC_Akt_AKT1_ST	Q9UQC2	GAB2	P31749	AKT1	T331	A338T	338	Missense	distal	7	no	9.973	10.034	EPSD	TCGA;COSMIC	7.780	Up-regulation
AGC_Akt_AKT1_ST	Q9UQC2	GAB2	P31749	AKT1	S368	S368N	368	Missense	central	0	yes	10.747	0.000	EPSD	TCGA;COSMIC	7.780	Loss
AGC_Akt_AKT1_ST	Q9UQC2	GAB2	P31749	AKT1	T385	V382F	382	Missense	distal	-3	no	9.593	10.864	EPSD	TCGA;COSMIC	7.780	Up-regulation
AGC_Akt_AKT1_ST	Q9UQC2	GAB2	P31749	AKT1	T385	R380I	380	Missense	distal	-5	no	9.593	5.026	EPSD	TCGA;COSMIC	7.780	Loss
AGC_Akt_AKT1_ST	Q9UQC2	GAB2	P31749	AKT1	T385	N390S	390	Missense	distal	5	no	9.593	9.628	EPSD	TCGA;COSMIC	7.780	Up-regulation
AGC_Akt_AKT1_ST	Q9UQC2	GAB2	P31749	AKT1	T385	R389H	389	Missense	distal	4	no	9.593	9.778	EPSD	TCGA	7.780	Up-regulation
AGC_Akt_AKT1_ST	Q9UQC2	GAB2	P31749	AKT1	T385	A384V	384	Missense	proximal	-1	no	9.593	9.579	EPSD	TCGA	7.780	Down-regulation
AGC_Akt_AKT1_ST	Q9UQC2	GAB2	P31749	AKT1	T391	N397S	397	Missense	distal	6	no	9.409	9.476	EPSD	TCGA;COSMIC	7.780	Up-regulation
AGC_Akt_AKT1_ST	Q9UQC2	GAB2	P31749	AKT1	T391	N390S	390	Missense	proximal	-1	no	9.409	9.427	EPSD	TCGA;COSMIC	7.780	Up-regulation
AGC_Akt_AKT1_ST	Q9UQC2	GAB2	P31749	AKT1	T391	R389H	389	Missense	proximal	-2	no	9.409	8.548	EPSD	TCGA	7.780	Down-regulation
AGC_Akt_AKT1_ST	Q9UQC2	GAB2	P31749	AKT1	T391	A394V	394	Missense	distal	3	no	9.409	9.376	EPSD	TCGA;COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	Q9UQC2	GAB2	P31749	AKT1	T391	A384V	384	Missense	distal	-7	no	9.409	9.280	EPSD	TCGA	7.780	Down-regulation
AGC_Akt_AKT1_ST	Q9UQC2	GAB2	P31749	AKT1	S404	E407Q	407	Missense	distal	3	no	10.238	10.206	EPSD	TCGA;COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	Q9UQC2	GAB2	P31749	AKT1	S404	N397S	397	Missense	distal	-7	no	10.238	10.352	EPSD	TCGA;COSMIC	7.780	Up-regulation
AGC_Akt_AKT1_ST	Q9UQC2	GAB2	P31749	AKT1	S404	S405F	405	Missense	proximal	1	no	10.238	10.255	EPSD	TCGA;COSMIC	7.780	Up-regulation
AGC_Akt_AKT1_ST	Q9UQC2	GAB2	P31749	AKT1	S404	R402Q	402	Missense	proximal	-2	no	10.238	9.725	EPSD	TCGA;COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	Q9UQC2	GAB2	P31749	AKT1	S405	E407Q	407	Missense	proximal	2	no	11.247	11.146	EPSD	TCGA;COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	Q9UQC2	GAB2	P31749	AKT1	S405	S405F	405	Missense	central	0	yes	11.247	0.000	EPSD	TCGA;COSMIC	7.780	Loss
AGC_Akt_AKT1_ST	Q9UQC2	GAB2	P31749	AKT1	S405	R402Q	402	Missense	distal	-3	no	11.247	4.035	EPSD	TCGA;COSMIC	7.780	Loss
AGC_Akt_AKT1_ST	Q9UQC2	GAB2	P31749	AKT1	S445	D450N	450	Missense	distal	5	no	11.344	11.384	EPSD	TCGA;COSMIC	7.780	Up-regulation
AGC_Akt_AKT1_ST	Q9UQC2	GAB2	P31749	AKT1	S445	D444E	444	Missense	proximal	-1	no	11.344	11.377	EPSD	TCGA;COSMIC	7.780	Up-regulation
AGC_Akt_AKT1_ST	Q9UQC2	GAB2	P31749	AKT1	S445	D450Y	450	Missense	distal	5	no	11.344	11.375	EPSD	TCGA;COSMIC	7.780	Up-regulation
AGC_Akt_AKT1_ST	Q9UQC2	GAB2	P31749	AKT1	S503	R500Q	500	Missense	distal	-3	no	10.024	2.813	EPSD	TCGA;COSMIC	7.780	Loss
AGC_Akt_AKT1_ST	Q9UQC2	GAB2	P31749	AKT1	S503	V498M	498	Missense	distal	-5	no	10.024	9.816	EPSD	TCGA;COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	Q9UQC2	GAB2	P31749	AKT1	T534	D537N	537	Missense	distal	3	no	8.861	8.916	EPSD	TCGA;COSMIC	7.780	Up-regulation
AGC_Akt_AKT1_ST	P23769	GATA2	P31749	AKT1	S182	P177S	177	Missense	distal	-5	no	8.663	8.203	EPSD	TCGA;ICGC;COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	P23769	GATA2	P31749	AKT1	S182	P175L	175	Missense	distal	-7	no	8.663	8.623	EPSD	TCGA;ICGC;COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	P23769	GATA2	P31749	AKT1	S288	R287C	287	Missense	proximal	-1	no	12.407	12.336	EPSD	TCGA;ICGC;COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	P23769	GATA2	P31749	AKT1	S288	R283C	283	Missense	distal	-5	no	12.407	8.330	EPSD	TCGA;ICGC;COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	P23769	GATA2	P31749	AKT1	S290	R287C	287	Missense	distal	-3	no	13.645	7.471	EPSD	TCGA;ICGC;COSMIC	7.780	Loss
AGC_Akt_AKT1_ST	P23769	GATA2	P31749	AKT1	S290	R283C	283	Missense	distal	-7	no	13.645	13.166	EPSD	TCGA;ICGC;COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	P23769	GATA2	P31749	AKT1	S340	S340L	340	Missense	central	0	yes	10.890	0.000	EPSD	TCGA;ICGC;COSMIC	7.780	Loss
AGC_Akt_AKT1_ST	P23769	GATA2	P31749	AKT1	S401	R396W	396	Missense	distal	-5	no	16.125	10.605	PhosphoSitePlus	TCGA;COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	P23769	GATA2	P31749	AKT1	S401	R396Q	396	Missense	distal	-5	no	16.125	11.898	PhosphoSitePlus	TCGA;COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	P23769	GATA2	P31749	AKT1	S401	N402H	402	Missense	proximal	1	no	16.125	16.036	PhosphoSitePlus	TCGA;ICGC;COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	P23769	GATA2	P31749	AKT1	S401	N397K	397	Missense	distal	-4	no	16.125	16.764	PhosphoSitePlus	TCGA;COSMIC	7.780	Up-regulation
AGC_Akt_AKT1_ST	P23769	GATA2	P31749	AKT1	S401	R398Q	398	Missense	distal	-3	no	16.125	8.914	PhosphoSitePlus	TCGA;ICGC;COSMIC;GDSC;CCLE	7.780	Down-regulation
AGC_Akt_AKT1_ST	P41002	CCNF	P31749	AKT1	T31	I32M	32	Missense	proximal	1	no	13.093	13.279	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	7.780	Up-regulation
AGC_Akt_AKT1_ST	P41002	CCNF	P31749	AKT1	T31	L35I	35	Missense	distal	4	no	13.093	13.166	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	7.780	Up-regulation
AGC_Akt_AKT1_ST	P41002	CCNF	P31749	AKT1	T31	R28Q	28	Missense	distal	-3	no	13.093	5.882	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	7.780	Loss
AGC_Akt_AKT1_ST	P41002	CCNF	P31749	AKT1	T31	D38Y	38	Missense	distal	7	no	13.093	13.128	EPSD;PhosphoSitePlus	TCGA;ICGC	7.780	Up-regulation
AGC_Akt_AKT1_ST	P41002	CCNF	P31749	AKT1	S577	G583C	583	Missense	distal	6	no	18.054	17.957	PhosphoSitePlus;EPSD	TCGA;ICGC;COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	P41002	CCNF	P31749	AKT1	S577	R572W	572	Missense	distal	-5	no	18.054	12.535	PhosphoSitePlus;EPSD	TCGA;ICGC;GDSC	7.780	Down-regulation
AGC_Akt_AKT1_ST	P41002	CCNF	P31749	AKT1	S754	P756L	756	Missense	proximal	2	no	10.612	10.403	EPSD	TCGA;ICGC;COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	P41002	CCNF	P31749	AKT1	S754	R751C	751	Missense	distal	-3	no	10.612	4.439	EPSD	TCGA;ICGC;COSMIC	7.780	Loss
AGC_Akt_AKT1_ST	Q05397	PTK2	P31749	AKT1	T24	G31C	31	Missense	distal	7	no	8.787	8.738	EPSD	TCGA;ICGC;COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	Q05397	PTK2	P31749	AKT1	S239	F243L	243	Missense	distal	4	no	10.719	10.711	EPSD	TCGA;ICGC	7.780	Down-regulation
AGC_Akt_AKT1_ST	Q05397	PTK2	P31749	AKT1	S239	E245D	245	Missense	distal	6	no	10.719	10.629	EPSD	TCGA;ICGC;COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	Q05397	PTK2	P31749	AKT1	S239	S239I	239	Missense	central	0	yes	10.719	0.000	EPSD	TCGA;ICGC	7.780	Loss
AGC_Akt_AKT1_ST	Q05397	PTK2	P31749	AKT1	S390	V389A	389	Missense	proximal	-1	no	10.293	10.307	EPSD	TCGA;ICGC;COSMIC	7.780	Up-regulation
AGC_Akt_AKT1_ST	Q05397	PTK2	P31749	AKT1	S390	D395Y	395	Missense	distal	5	no	10.293	10.324	EPSD	TCGA;ICGC	7.780	Up-regulation
AGC_Akt_AKT1_ST	Q05397	PTK2	P31749	AKT1	S390	R385Q	385	Missense	distal	-5	no	10.293	6.065	EPSD	TCGA;ICGC	7.780	Loss
AGC_Akt_AKT1_ST	Q05397	PTK2	P31749	AKT1	S390	T386I	386	Missense	distal	-4	no	10.293	8.855	EPSD	TCGA;ICGC;COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	Q05397	PTK2	P31749	AKT1	S390	R385W	385	Missense	distal	-5	no	10.293	4.773	EPSD	TCGA;ICGC;COSMIC	7.780	Loss
AGC_Akt_AKT1_ST	Q05397	PTK2	P31749	AKT1	S517	S517I	517	Missense	central	0	yes	12.096	0.000	EPSD	TCGA;ICGC;COSMIC	7.780	Loss
AGC_Akt_AKT1_ST	Q05397	PTK2	P31749	AKT1	S517	S522Y	522	Missense	distal	5	no	12.096	12.052	EPSD	TCGA;ICGC;COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	Q05397	PTK2	P31749	AKT1	S677	L672R	672	Missense	distal	-5	no	5.496	9.622	EPSD	TCGA;ICGC;COSMIC	7.780	Gain
AGC_Akt_AKT1_ST	Q05397	PTK2	P31749	AKT1	S695	R696S	696	Missense	proximal	1	no	15.318	15.173	PhosphoSitePlus;EPSD	TCGA;COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	Q05397	PTK2	P31749	AKT1	S695	R690C	690	Missense	distal	-5	no	15.318	11.241	PhosphoSitePlus;EPSD	TCGA;ICGC;COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	Q05397	PTK2	P31749	AKT1	T700	G706V	706	Missense	distal	6	no	11.391	11.382	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	Q05397	PTK2	P31749	AKT1	T700	R696S	696	Missense	distal	-4	no	11.391	11.305	EPSD;PhosphoSitePlus	TCGA;COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	Q05397	PTK2	P31749	AKT1	S702	G706V	706	Missense	distal	4	no	8.751	8.758	EPSD	TCGA;ICGC;COSMIC	7.780	Up-regulation
AGC_Akt_AKT1_ST	Q05397	PTK2	P31749	AKT1	S702	R696S	696	Missense	distal	-6	no	8.751	8.717	EPSD	TCGA;COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	Q05397	PTK2	P31749	AKT1	S722	S725F	725	Missense	distal	3	no	9.370	9.272	EPSD	TCGA;ICGC	7.780	Down-regulation
AGC_Akt_AKT1_ST	Q05397	PTK2	P31749	AKT1	S722	P718L	718	Missense	distal	-4	no	9.370	8.983	EPSD	TCGA;ICGC;COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	Q05397	PTK2	P31749	AKT1	S722	P723L	723	Missense	proximal	1	no	9.370	9.624	EPSD	TCGA;ICGC;COSMIC	7.780	Up-regulation
AGC_Akt_AKT1_ST	P54253	ATXN1	P31749	AKT1	T22	E27K	27	Missense	distal	5	no	8.868	8.902	EPSD	TCGA;ICGC;COSMIC	7.780	Up-regulation
AGC_Akt_AKT1_ST	P54253	ATXN1	P31749	AKT1	S262	P264L	264	Missense	proximal	2	no	12.639	12.429	EPSD	TCGA;ICGC;COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	P54253	ATXN1	P31749	AKT1	S262	P267L	267	Missense	distal	5	no	12.639	12.625	EPSD	TCGA;ICGC;COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	P54253	ATXN1	P31749	AKT1	S262	V268I	268	Missense	distal	6	no	12.639	12.588	EPSD	TCGA;ICGC;COSMIC;CCLE	7.780	Down-regulation
AGC_Akt_AKT1_ST	P54253	ATXN1	P31749	AKT1	S312	E310K	310	Missense	proximal	-2	no	8.426	9.085	EPSD	TCGA;ICGC;COSMIC	7.780	Up-regulation
AGC_Akt_AKT1_ST	P54253	ATXN1	P31749	AKT1	S312	R313W	313	Missense	proximal	1	no	8.426	8.133	EPSD	TCGA;ICGC;COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	P54253	ATXN1	P31749	AKT1	S775	A776V	776	Missense	proximal	1	no	17.674	17.746	PhosphoSitePlus	TCGA;ICGC;COSMIC	7.780	Up-regulation
AGC_Akt_AKT1_ST	P54253	ATXN1	P31749	AKT1	S775	K771E	771	Missense	distal	-4	no	17.674	17.090	PhosphoSitePlus	TCGA;ICGC;COSMIC;GDSC;CCLE	7.780	Down-regulation
AGC_Akt_AKT1_ST	Q9BRS8	LARP6	P31749	AKT1	T69	E75K	75	Missense	distal	6	no	10.900	10.969	EPSD	TCGA;ICGC;COSMIC	7.780	Up-regulation
AGC_Akt_AKT1_ST	Q9BRS8	LARP6	P31749	AKT1	S247	R249S	249	Missense	proximal	2	no	11.465	11.637	EPSD	TCGA;ICGC;COSMIC	7.780	Up-regulation
AGC_Akt_AKT1_ST	Q9BRS8	LARP6	P31749	AKT1	S447	Q444H	444	Missense	distal	-3	no	5.562	8.074	EPSD	TCGA;ICGC;COSMIC	7.780	Gain
AGC_Akt_AKT1_ST	Q9BRS8	LARP6	P31749	AKT1	S451	G449S	449	Missense	proximal	-2	no	7.702	8.397	PhosphoSitePlus	TCGA;ICGC;COSMIC	7.780	Gain
AGC_Akt_AKT1_ST	Q9BRS8	LARP6	P31749	AKT1	S451	P452L	452	Missense	proximal	1	no	7.702	7.956	PhosphoSitePlus	TCGA;ICGC;COSMIC	7.780	Gain
AGC_Akt_AKT1_ST	P07550	ADRB2	P31749	AKT1	T68	R63H	63	Missense	distal	-5	no	8.233	5.139	EPSD	TCGA;ICGC;COSMIC	7.780	Loss
AGC_Akt_AKT1_ST	P07550	ADRB2	P31749	AKT1	S262	S262F	262	Missense	central	0	yes	12.766	0.000	EPSD	TCGA;ICGC;COSMIC	7.780	Loss
AGC_Akt_AKT1_ST	P07550	ADRB2	P31749	AKT1	S262	K267T	267	Missense	distal	5	no	12.766	12.765	EPSD	TCGA;ICGC	7.780	Down-regulation
AGC_Akt_AKT1_ST	P07550	ADRB2	P31749	AKT1	S346	R343C	343	Missense	distal	-3	no	13.056	6.883	PhosphoSitePlus	TCGA;ICGC;COSMIC	7.780	Loss
AGC_Akt_AKT1_ST	P07550	ADRB2	P31749	AKT1	S346	L339R	339	Missense	distal	-7	no	13.056	13.346	PhosphoSitePlus	TCGA;ICGC;COSMIC	7.780	Up-regulation
AGC_Akt_AKT1_ST	P07550	ADRB2	P31749	AKT1	S401	S396R	396	Missense	distal	-5	no	5.734	10.204	EPSD	TCGA;ICGC;COSMIC	7.780	Gain
AGC_Akt_AKT1_ST	P07550	ADRB2	P31749	AKT1	S407	D400N	400	Missense	distal	-7	no	13.355	13.612	EPSD	TCGA;ICGC;COSMIC	7.780	Up-regulation
AGC_Akt_AKT1_ST	P04150	NR3C1	P31749	AKT1	S16	P9H	9	Missense	distal	-7	no	8.249	8.198	EPSD	TCGA;COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	P04150	NR3C1	P31749	AKT1	S134	P136L	136	Missense	proximal	2	no	12.534	12.324	PhosphoSitePlus	TCGA;ICGC;COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	P04150	NR3C1	P31749	AKT1	S134	K140N	140	Missense	distal	6	no	12.534	12.456	PhosphoSitePlus	TCGA;ICGC;COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	P04150	NR3C1	P31749	AKT1	S404	S404Y	404	Missense	central	0	yes	10.029	0.000	EPSD	TCGA;ICGC	7.780	Loss
AGC_Akt_AKT1_ST	Q9H4A3	WNK1	P31749	AKT1	T60	D62G	62	Missense	proximal	2	no	14.328	14.595	PhosphoSitePlus	TCGA;ICGC;COSMIC	7.780	Up-regulation
AGC_Akt_AKT1_ST	Q9H4A3	WNK1	P31749	AKT1	T71	T74A	74	Missense	distal	3	no	9.211	9.154	EPSD	TCGA;ICGC;COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	Q9H4A3	WNK1	P31749	AKT1	S167	T160N	160	Missense	distal	-7	no	12.586	12.422	EPSD	TCGA;ICGC;COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	Q9H4A3	WNK1	P31749	AKT1	S167	V172E	172	Missense	distal	5	no	12.586	12.613	EPSD	TCGA;ICGC;COSMIC	7.780	Up-regulation
AGC_Akt_AKT1_ST	Q9H4A3	WNK1	P31749	AKT1	S185	R182T	182	Missense	distal	-3	no	11.024	4.003	EPSD	TCGA;ICGC;COSMIC	7.780	Loss
AGC_Akt_AKT1_ST	Q9H4A3	WNK1	P31749	AKT1	S378	L374Q	374	Missense	distal	-4	no	8.741	9.330	EPSD	TCGA;ICGC;COSMIC	7.780	Up-regulation
AGC_Akt_AKT1_ST	Q9H4A3	WNK1	P31749	AKT1	S378	R376W	376	Missense	proximal	-2	no	8.741	7.487	EPSD	TCGA;ICGC	7.780	Loss
AGC_Akt_AKT1_ST	Q9H4A3	WNK1	P31749	AKT1	T436	R433L	433	Missense	distal	-3	no	9.482	2.488	EPSD	TCGA;ICGC;COSMIC	7.780	Loss
AGC_Akt_AKT1_ST	Q9H4A3	WNK1	P31749	AKT1	T436	R434H	434	Missense	proximal	-2	no	9.482	8.621	EPSD	TCGA;ICGC;COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	Q9H4A3	WNK1	P31749	AKT1	S437	R433L	433	Missense	distal	-4	no	11.159	9.950	EPSD	TCGA;ICGC;COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	Q9H4A3	WNK1	P31749	AKT1	S437	R434H	434	Missense	distal	-3	no	11.159	6.461	EPSD	TCGA;ICGC;COSMIC	7.780	Loss
AGC_Akt_AKT1_ST	Q9H4A3	WNK1	P31749	AKT1	S1105	R1109L	1109	Missense	distal	4	no	9.494	9.672	EPSD	TCGA;COSMIC	7.780	Up-regulation
AGC_Akt_AKT1_ST	Q9H4A3	WNK1	P31749	AKT1	S1105	R1109H	1109	Missense	distal	4	no	9.494	9.679	EPSD	TCGA	7.780	Up-regulation
AGC_Akt_AKT1_ST	Q9H4A3	WNK1	P31749	AKT1	S1105	R1100W	1100	Missense	distal	-5	no	9.494	3.974	EPSD	TCGA;COSMIC	7.780	Loss
AGC_Akt_AKT1_ST	Q9H4A3	WNK1	P31749	AKT1	S1105	R1111Q	1111	Missense	distal	6	no	9.494	9.423	EPSD	TCGA	7.780	Down-regulation
AGC_Akt_AKT1_ST	Q9H4A3	WNK1	P31749	AKT1	S1108	R1109L	1109	Missense	proximal	1	no	9.070	9.024	EPSD	TCGA;COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	Q9H4A3	WNK1	P31749	AKT1	S1108	R1109H	1109	Missense	proximal	1	no	9.070	8.747	EPSD	TCGA	7.780	Down-regulation
AGC_Akt_AKT1_ST	Q9H4A3	WNK1	P31749	AKT1	S1108	R1111Q	1111	Missense	distal	3	no	9.070	9.014	EPSD	TCGA	7.780	Down-regulation
AGC_Akt_AKT1_ST	Q9H4A3	WNK1	P31749	AKT1	S1110	R1109L	1109	Missense	proximal	-1	no	10.716	10.677	EPSD	TCGA;COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	Q9H4A3	WNK1	P31749	AKT1	S1110	R1109H	1109	Missense	proximal	-1	no	10.716	10.671	EPSD	TCGA	7.780	Down-regulation
AGC_Akt_AKT1_ST	Q9H4A3	WNK1	P31749	AKT1	S1110	R1111Q	1111	Missense	proximal	1	no	10.716	10.421	EPSD	TCGA	7.780	Down-regulation
AGC_Akt_AKT1_ST	Q9H4A3	WNK1	P31749	AKT1	S1116	R1109L	1109	Missense	distal	-7	no	10.085	9.795	EPSD	TCGA;COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	Q9H4A3	WNK1	P31749	AKT1	S1116	R1109H	1109	Missense	distal	-7	no	10.085	9.783	EPSD	TCGA	7.780	Down-regulation
AGC_Akt_AKT1_ST	Q9H4A3	WNK1	P31749	AKT1	S1116	R1111Q	1111	Missense	distal	-5	no	10.085	5.857	EPSD	TCGA	7.780	Loss
AGC_Akt_AKT1_ST	Q9H4A3	WNK1	P31749	AKT1	S1261	P1264S	1264	Missense	distal	3	no	10.878	10.959	EPSD	TCGA;COSMIC	7.780	Up-regulation
AGC_Akt_AKT1_ST	Q9H4A3	WNK1	P31749	AKT1	S1261	E1265K	1265	Missense	distal	4	no	10.878	10.777	EPSD	TCGA;COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	Q9H4A3	WNK1	P31749	AKT1	S1261	R1267L	1267	Missense	distal	6	no	10.878	10.776	EPSD	TCGA;COSMIC;GDSC;CCLE	7.780	Down-regulation
AGC_Akt_AKT1_ST	Q9H4A3	WNK1	P31749	AKT1	S1261	A1254V	1254	Missense	distal	-7	no	10.878	10.750	EPSD	TCGA;COSMIC;CCLE	7.780	Down-regulation
AGC_Akt_AKT1_ST	Q9H4A3	WNK1	P31749	AKT1	S1961	F1958L	1958	Missense	distal	-3	no	8.137	6.738	EPSD	TCGA;COSMIC	7.780	Loss
AGC_Akt_AKT1_ST	Q9H4A3	WNK1	P31749	AKT1	S1961	R1957C	1957	Missense	distal	-4	no	8.137	6.459	EPSD	TCGA;COSMIC	7.780	Loss
AGC_Akt_AKT1_ST	Q9H4A3	WNK1	P31749	AKT1	S1961	R1957H	1957	Missense	distal	-4	no	8.137	7.079	EPSD	TCGA;COSMIC	7.780	Loss
AGC_Akt_AKT1_ST	Q9H4A3	WNK1	P31749	AKT1	T2128	S2135F	2135	Missense	distal	7	no	15.861	15.787	EPSD	TCGA	7.780	Down-regulation
AGC_Akt_AKT1_ST	Q9H4A3	WNK1	P31749	AKT1	S2140	S2145N	2145	Missense	distal	5	no	11.743	11.709	EPSD	TCGA;COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	Q9H4A3	WNK1	P31749	AKT1	S2140	S2135F	2135	Missense	distal	-5	no	11.743	12.692	EPSD	TCGA	7.780	Up-regulation
AGC_Akt_AKT1_ST	Q9H4A3	WNK1	P31749	AKT1	T2245	H2251P	2251	Missense	distal	6	no	11.901	11.929	EPSD	TCGA;COSMIC	7.780	Up-regulation
AGC_Akt_AKT1_ST	Q9H4A3	WNK1	P31749	AKT1	T2245	T2239M	2239	Missense	distal	-6	no	11.901	11.809	EPSD	TCGA;COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	Q9H4A3	WNK1	P31749	AKT1	T2247	H2251P	2251	Missense	distal	4	no	8.204	8.164	EPSD	TCGA;COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	Q9H4A3	WNK1	P31749	AKT1	S2270	S2265L	2265	Missense	distal	-5	no	10.968	11.312	EPSD	TCGA;COSMIC	7.780	Up-regulation
AGC_Akt_AKT1_ST	Q9H4A3	WNK1	P31749	AKT1	S2372	S2370F	2370	Missense	proximal	-2	no	12.008	11.141	EPSD	TCGA;COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	Q9NPC1	LTB4R2	P31749	AKT1	S246	A251V	251	Missense	distal	5	no	11.137	11.129	EPSD	TCGA;ICGC;COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	Q9NPC1	LTB4R2	P31749	AKT1	T355	L358I	358	Missense	distal	3	no	15.917	15.883	EPSD	TCGA;ICGC;COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	P21333	FLNA	P31749	AKT1	S343	K338Q	338	Missense	distal	-5	no	14.230	12.399	EPSD	TCGA;ICGC;COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	P21333	FLNA	P31749	AKT1	S343	P348S	348	Missense	distal	5	no	14.230	14.282	EPSD	TCGA;ICGC;COSMIC	7.780	Up-regulation
AGC_Akt_AKT1_ST	P21333	FLNA	P31749	AKT1	S440	R437Q	437	Missense	distal	-3	no	11.952	4.740	EPSD	TCGA;ICGC;COSMIC	7.780	Loss
AGC_Akt_AKT1_ST	P21333	FLNA	P31749	AKT1	S440	R443H	443	Missense	distal	3	no	11.952	11.868	EPSD	TCGA;ICGC	7.780	Down-regulation
AGC_Akt_AKT1_ST	P21333	FLNA	P31749	AKT1	S440	R443C	443	Missense	distal	3	no	11.952	11.791	EPSD	TCGA;ICGC;COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	P21333	FLNA	P31749	AKT1	T833	T839M	839	Missense	distal	6	no	9.292	9.173	EPSD	TCGA;ICGC;COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	P21333	FLNA	P31749	AKT1	T833	D830Y	830	Missense	distal	-3	no	9.292	7.653	EPSD	TCGA;ICGC;COSMIC	7.780	Loss
AGC_Akt_AKT1_ST	P21333	FLNA	P31749	AKT1	T833	K837R	837	Missense	distal	4	no	9.292	9.325	EPSD	TCGA;ICGC;COSMIC	7.780	Up-regulation
AGC_Akt_AKT1_ST	P21333	FLNA	P31749	AKT1	T833	N829T	829	Missense	distal	-4	no	9.292	9.915	EPSD	TCGA;ICGC;COSMIC	7.780	Up-regulation
AGC_Akt_AKT1_ST	P21333	FLNA	P31749	AKT1	T833	R828C	828	Missense	distal	-5	no	9.292	5.215	EPSD	TCGA;ICGC;COSMIC	7.780	Loss
AGC_Akt_AKT1_ST	P21333	FLNA	P31749	AKT1	T833	R828H	828	Missense	distal	-5	no	9.292	6.197	EPSD	TCGA;ICGC;COSMIC	7.780	Loss
AGC_Akt_AKT1_ST	P21333	FLNA	P31749	AKT1	T1275	R1272C	1272	Missense	distal	-3	no	11.002	4.829	EPSD	TCGA;ICGC;COSMIC	7.780	Loss
AGC_Akt_AKT1_ST	P21333	FLNA	P31749	AKT1	T1275	Q1268H	1268	Missense	distal	-7	no	11.002	10.895	EPSD	TCGA;ICGC	7.780	Down-regulation
AGC_Akt_AKT1_ST	P21333	FLNA	P31749	AKT1	T1275	A1282T	1282	Missense	distal	7	no	11.002	11.063	EPSD	TCGA;ICGC	7.780	Up-regulation
AGC_Akt_AKT1_ST	P21333	FLNA	P31749	AKT1	T1275	R1272H	1272	Missense	distal	-3	no	11.002	6.304	EPSD	TCGA;ICGC;COSMIC	7.780	Loss
AGC_Akt_AKT1_ST	P21333	FLNA	P31749	AKT1	T1286	R1283W	1283	Missense	distal	-3	no	12.037	3.097	EPSD	TCGA;ICGC;COSMIC	7.780	Loss
AGC_Akt_AKT1_ST	P21333	FLNA	P31749	AKT1	T1286	P1291L	1291	Missense	distal	5	no	12.037	12.024	EPSD	TCGA;ICGC;COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	P21333	FLNA	P31749	AKT1	T1286	A1282T	1282	Missense	distal	-4	no	12.037	12.815	EPSD	TCGA;ICGC	7.780	Up-regulation
AGC_Akt_AKT1_ST	P21333	FLNA	P31749	AKT1	T1288	R1283W	1283	Missense	distal	-5	no	8.034	2.514	EPSD	TCGA;ICGC;COSMIC	7.780	Loss
AGC_Akt_AKT1_ST	P21333	FLNA	P31749	AKT1	T1288	K1294N	1294	Missense	distal	6	no	8.034	7.956	EPSD	TCGA;ICGC;COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	P21333	FLNA	P31749	AKT1	T1288	P1291L	1291	Missense	distal	3	no	8.034	8.018	EPSD	TCGA;ICGC;COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	P21333	FLNA	P31749	AKT1	T1288	A1282T	1282	Missense	distal	-6	no	8.034	8.120	EPSD	TCGA;ICGC	7.780	Up-regulation
AGC_Akt_AKT1_ST	P21333	FLNA	P31749	AKT1	T1557	G1554R	1554	Missense	distal	-3	no	2.965	9.721	EPSD	TCGA;ICGC;COSMIC	7.780	Gain
AGC_Akt_AKT1_ST	P21333	FLNA	P31749	AKT1	S1812	A1816T	1816	Missense	distal	4	no	9.361	9.232	EPSD	TCGA	7.780	Down-regulation
AGC_Akt_AKT1_ST	P21333	FLNA	P31749	AKT1	S1812	R1809W	1809	Missense	distal	-3	no	9.361	0.420	EPSD	TCGA	7.780	Loss
AGC_Akt_AKT1_ST	P21333	FLNA	P31749	AKT1	S1812	G1813C	1813	Missense	proximal	1	no	9.361	9.282	EPSD	TCGA;COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	P21333	FLNA	P31749	AKT1	S2032	V2030M	2030	Missense	proximal	-2	no	7.493	7.844	EPSD	TCGA;COSMIC	7.780	Gain
AGC_Akt_AKT1_ST	P21333	FLNA	P31749	AKT1	S2152	S2152L	2152	Missense	central	0	yes	14.900	0.000	PhosphoSitePlus	TCGA;COSMIC	7.780	Loss
AGC_Akt_AKT1_ST	P21333	FLNA	P31749	AKT1	S2152	R2148S	2148	Missense	distal	-4	no	14.900	14.814	PhosphoSitePlus	TCGA;COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	P21333	FLNA	P31749	AKT1	T2336	R2334H	2334	Missense	proximal	-2	no	12.361	11.500	EPSD	TCGA;COSMIC;GDSC;CCLE	7.780	Down-regulation
AGC_Akt_AKT1_ST	P21333	FLNA	P31749	AKT1	T2336	E2342K	2342	Missense	distal	6	no	12.361	12.430	EPSD	TCGA	7.780	Up-regulation
AGC_Akt_AKT1_ST	P21333	FLNA	P31749	AKT1	T2336	A2332T	2332	Missense	distal	-4	no	12.361	13.139	EPSD	TCGA;COSMIC	7.780	Up-regulation
AGC_Akt_AKT1_ST	P21333	FLNA	P31749	AKT1	S2338	R2334H	2334	Missense	distal	-4	no	9.813	8.754	EPSD	TCGA;COSMIC;GDSC;CCLE	7.780	Down-regulation
AGC_Akt_AKT1_ST	P21333	FLNA	P31749	AKT1	S2338	E2342K	2342	Missense	distal	4	no	9.813	9.712	EPSD	TCGA	7.780	Down-regulation
AGC_Akt_AKT1_ST	P21333	FLNA	P31749	AKT1	S2338	A2332T	2332	Missense	distal	-6	no	9.813	9.899	EPSD	TCGA;COSMIC	7.780	Up-regulation
AGC_Akt_AKT1_ST	P21333	FLNA	P31749	AKT1	S2372	S2372L	2372	Missense	central	0	yes	8.250	0.000	EPSD	TCGA;COSMIC	7.780	Loss
AGC_Akt_AKT1_ST	P21333	FLNA	P31749	AKT1	S2372	H2369Y	2369	Missense	distal	-3	no	8.250	5.359	EPSD	TCGA;COSMIC	7.780	Loss
AGC_Akt_AKT1_ST	P21333	FLNA	P31749	AKT1	S2372	A2374S	2374	Missense	proximal	2	no	8.250	8.625	EPSD	TCGA;COSMIC	7.780	Up-regulation
AGC_Akt_AKT1_ST	P21333	FLNA	P31749	AKT1	S2523	G2518C	2518	Missense	distal	-5	no	11.041	11.028	EPSD	TCGA;COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	P21333	FLNA	P31749	AKT1	S2523	S2526I	2526	Missense	distal	3	no	11.041	10.910	EPSD	TCGA	7.780	Down-regulation
AGC_Akt_AKT1_ST	P21333	FLNA	P31749	AKT1	S2615	R2612W	2612	Missense	distal	-3	no	12.935	3.995	EPSD	TCGA;GDSC	7.780	Loss
AGC_Akt_AKT1_ST	P21333	FLNA	P31749	AKT1	S2615	V2609M	2609	Missense	distal	-6	no	12.935	12.949	EPSD	TCGA;COSMIC;GDSC;CCLE	7.780	Up-regulation
AGC_Akt_AKT1_ST	P21333	FLNA	P31749	AKT1	S2615	S2617P	2617	Missense	proximal	2	no	12.935	12.599	EPSD	TCGA;COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	P21333	FLNA	P31749	AKT1	S2617	R2612W	2612	Missense	distal	-5	no	8.044	2.524	EPSD	TCGA;GDSC	7.780	Loss
AGC_Akt_AKT1_ST	P21333	FLNA	P31749	AKT1	S2617	S2617P	2617	Missense	central	0	yes	8.044	0.000	EPSD	TCGA;COSMIC	7.780	Loss
AGC_Akt_AKT1_ST	P30291	WEE1	P31749	AKT1	S212	E218K	218	Missense	distal	6	no	13.593	13.662	EPSD	TCGA;ICGC;COSMIC	7.780	Up-regulation
AGC_Akt_AKT1_ST	P30291	WEE1	P31749	AKT1	S212	L213R	213	Missense	proximal	1	no	13.593	13.639	EPSD	TCGA;ICGC;COSMIC	7.780	Up-regulation
AGC_Akt_AKT1_ST	P30291	WEE1	P31749	AKT1	S212	V206F	206	Missense	distal	-6	no	13.593	13.594	EPSD	TCGA;ICGC;COSMIC	7.780	Up-regulation
AGC_Akt_AKT1_ST	P30291	WEE1	P31749	AKT1	T257	D261H	261	Missense	distal	4	no	14.609	14.580	EPSD	TCGA;ICGC;COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	P30291	WEE1	P31749	AKT1	T257	R256T	256	Missense	proximal	-1	no	14.609	14.604	EPSD	TCGA;ICGC;COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	P30291	WEE1	P31749	AKT1	T257	G264S	264	Missense	distal	7	no	14.609	14.682	EPSD	TCGA;ICGC;COSMIC	7.780	Up-regulation
AGC_Akt_AKT1_ST	P30291	WEE1	P31749	AKT1	T257	R256K	256	Missense	proximal	-1	no	14.609	14.605	EPSD	TCGA;ICGC;COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	P30291	WEE1	P31749	AKT1	S472	P473L	473	Missense	proximal	1	no	10.961	11.215	EPSD	TCGA;ICGC;COSMIC	7.780	Up-regulation
AGC_Akt_AKT1_ST	P30291	WEE1	P31749	AKT1	S559	H566R	566	Missense	distal	7	no	10.760	10.832	EPSD	TCGA;ICGC;COSMIC	7.780	Up-regulation
AGC_Akt_AKT1_ST	P30291	WEE1	P31749	AKT1	S571	H566R	566	Missense	distal	-5	no	5.874	8.969	EPSD	TCGA;ICGC;COSMIC	7.780	Gain
AGC_Akt_AKT1_ST	P78371	CCT2	P31749	AKT1	S28	A34T	34	Missense	distal	6	no	10.688	10.791	EPSD	TCGA;ICGC;COSMIC	7.780	Up-regulation
AGC_Akt_AKT1_ST	P78371	CCT2	P31749	AKT1	S60	D58N	58	Missense	proximal	-2	no	9.293	10.001	EPSD	TCGA;ICGC;COSMIC	7.780	Up-regulation
AGC_Akt_AKT1_ST	P78371	CCT2	P31749	AKT1	T134	I127T	127	Missense	distal	-7	no	10.179	10.602	EPSD	TCGA;ICGC;COSMIC	7.780	Up-regulation
AGC_Akt_AKT1_ST	P78371	CCT2	P31749	AKT1	T134	A128V	128	Missense	distal	-6	no	10.179	10.159	EPSD	TCGA;ICGC;COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	P78371	CCT2	P31749	AKT1	S143	S150F	150	Missense	distal	7	no	8.120	8.046	EPSD	TCGA;ICGC;COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	P78371	CCT2	P31749	AKT1	S260	E266Q	266	Missense	distal	6	no	13.404	13.391	PhosphoSitePlus	TCGA;ICGC;COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	P78371	CCT2	P31749	AKT1	T379	Q381H	381	Missense	proximal	2	no	10.191	9.947	EPSD	TCGA;ICGC;COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	P78371	CCT2	P31749	AKT1	T379	Q380E	380	Missense	proximal	1	no	10.191	10.245	EPSD	TCGA;ICGC;COSMIC	7.780	Up-regulation
AGC_Akt_AKT1_ST	P41279	MAP3K8	P31749	AKT1	T80	D83Y	83	Missense	distal	3	no	8.593	8.636	EPSD	TCGA;ICGC;COSMIC	7.780	Up-regulation
AGC_Akt_AKT1_ST	P41279	MAP3K8	P31749	AKT1	S400	E393Q	393	Missense	distal	-7	no	11.067	11.079	PhosphoSitePlus	TCGA;ICGC;COSMIC	7.780	Up-regulation
AGC_Akt_AKT1_ST	P41279	MAP3K8	P31749	AKT1	S400	R397H	397	Missense	distal	-3	no	11.067	6.368	PhosphoSitePlus	TCGA;ICGC;COSMIC;CCLE	7.780	Loss
AGC_Akt_AKT1_ST	P41279	MAP3K8	P31749	AKT1	S413	P420S	420	Missense	distal	7	no	15.465	15.523	EPSD	TCGA;ICGC;COSMIC	7.780	Up-regulation
AGC_Akt_AKT1_ST	P41279	MAP3K8	P31749	AKT1	S413	K409R	409	Missense	distal	-4	no	15.465	15.478	EPSD	TCGA;ICGC;COSMIC	7.780	Up-regulation
AGC_Akt_AKT1_ST	P41279	MAP3K8	P31749	AKT1	S413	R408C	408	Missense	distal	-5	no	15.465	11.388	EPSD	TCGA;ICGC;COSMIC;GDSC;CCLE	7.780	Down-regulation
AGC_Akt_AKT1_ST	P41279	MAP3K8	P31749	AKT1	S443	R442H	442	Missense	proximal	-1	no	12.799	12.755	EPSD	TCGA;ICGC;COSMIC;GDSC;CCLE	7.780	Down-regulation
AGC_Akt_AKT1_ST	P41279	MAP3K8	P31749	AKT1	S443	L444V	444	Missense	proximal	1	no	12.799	12.699	EPSD	TCGA;ICGC;COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	P41279	MAP3K8	P31749	AKT1	S443	A450S	450	Missense	distal	7	no	12.799	12.850	EPSD	TCGA;ICGC;COSMIC	7.780	Up-regulation
AGC_Akt_AKT1_ST	P41279	MAP3K8	P31749	AKT1	S443	R440K	440	Missense	distal	-3	no	12.799	8.279	EPSD	TCGA;ICGC;COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	Q96QB1	DLC1	P31749	AKT1	S354	R351W	351	Missense	distal	-3	no	14.062	5.122	EPSD	TCGA;ICGC;COSMIC;GDSC;CCLE	7.780	Loss
AGC_Akt_AKT1_ST	Q96QB1	DLC1	P31749	AKT1	S354	M355I	355	Missense	proximal	1	no	14.062	13.876	EPSD	TCGA;ICGC;COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	Q96QB1	DLC1	P31749	AKT1	S354	D348H	348	Missense	distal	-6	no	14.062	14.096	EPSD	TCGA;ICGC;COSMIC	7.780	Up-regulation
AGC_Akt_AKT1_ST	Q96QB1	DLC1	P31749	AKT1	S354	A350E	350	Missense	distal	-4	no	14.062	14.272	EPSD	TCGA;ICGC;COSMIC	7.780	Up-regulation
AGC_Akt_AKT1_ST	Q96QB1	DLC1	P31749	AKT1	S523	I516M	516	Missense	distal	-7	no	10.489	10.645	EPSD	TCGA;COSMIC	7.780	Up-regulation
AGC_Akt_AKT1_ST	Q96QB1	DLC1	P31749	AKT1	S523	D525E	525	Missense	proximal	2	no	10.489	10.899	EPSD	TCGA;ICGC;COSMIC	7.780	Up-regulation
AGC_Akt_AKT1_ST	Q96QB1	DLC1	P31749	AKT1	S523	D529Y	529	Missense	distal	6	no	10.489	10.549	EPSD	TCGA;ICGC;COSMIC	7.780	Up-regulation
AGC_Akt_AKT1_ST	Q96QB1	DLC1	P31749	AKT1	S523	H519D	519	Missense	distal	-4	no	10.489	10.174	EPSD	TCGA;COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	Q96QB1	DLC1	P31749	AKT1	S548	E552Q	552	Missense	distal	4	no	8.566	8.621	EPSD	TCGA;COSMIC	7.780	Up-regulation
AGC_Akt_AKT1_ST	Q96QB1	DLC1	P31749	AKT1	S598	R595H	595	Missense	distal	-3	no	10.137	5.439	EPSD	TCGA;ICGC;COSMIC	7.780	Loss
AGC_Akt_AKT1_ST	Q96QB1	DLC1	P31749	AKT1	S598	R595C	595	Missense	distal	-3	no	10.137	3.964	EPSD	TCGA;COSMIC	7.780	Loss
AGC_Akt_AKT1_ST	Q96QB1	DLC1	P31749	AKT1	S598	S593F	593	Missense	distal	-5	no	10.137	11.086	EPSD	TCGA;COSMIC	7.780	Up-regulation
AGC_Akt_AKT1_ST	Q96QB1	DLC1	P31749	AKT1	S598	P604S	604	Missense	distal	6	no	10.137	10.231	EPSD	TCGA;COSMIC	7.780	Up-regulation
AGC_Akt_AKT1_ST	Q96QB1	DLC1	P31749	AKT1	T600	R595H	595	Missense	distal	-5	no	8.833	5.738	EPSD	TCGA;ICGC;COSMIC	7.780	Loss
AGC_Akt_AKT1_ST	Q96QB1	DLC1	P31749	AKT1	T600	A607V	607	Missense	distal	7	no	8.833	8.828	EPSD	TCGA;COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	Q96QB1	DLC1	P31749	AKT1	T600	R595C	595	Missense	distal	-5	no	8.833	4.756	EPSD	TCGA;COSMIC	7.780	Loss
AGC_Akt_AKT1_ST	Q96QB1	DLC1	P31749	AKT1	T600	S593F	593	Missense	distal	-7	no	8.833	8.555	EPSD	TCGA;COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	Q96QB1	DLC1	P31749	AKT1	T600	P604S	604	Missense	distal	4	no	8.833	8.677	EPSD	TCGA;COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	Q96QB1	DLC1	P31749	AKT1	S620	A614T	614	Missense	distal	-6	no	11.667	11.753	EPSD	TCGA;COSMIC	7.780	Up-regulation
AGC_Akt_AKT1_ST	Q96QB1	DLC1	P31749	AKT1	S620	V624I	624	Missense	distal	4	no	11.667	11.749	EPSD	TCGA;ICGC;COSMIC	7.780	Up-regulation
AGC_Akt_AKT1_ST	Q96QB1	DLC1	P31749	AKT1	S620	P616H	616	Missense	distal	-4	no	11.667	11.431	EPSD	TCGA;ICGC;COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	Q96QB1	DLC1	P31749	AKT1	S620	S620F	620	Missense	central	0	yes	11.667	0.000	EPSD	TCGA;COSMIC;GDSC;CCLE	7.780	Loss
AGC_Akt_AKT1_ST	Q96QB1	DLC1	P31749	AKT1	S620	R617Q	617	Missense	distal	-3	no	11.667	4.456	EPSD	TCGA;COSMIC	7.780	Loss
AGC_Akt_AKT1_ST	Q96QB1	DLC1	P31749	AKT1	S666	R670P	670	Missense	distal	4	no	9.369	9.514	EPSD	TCGA;ICGC;COSMIC	7.780	Up-regulation
AGC_Akt_AKT1_ST	Q96QB1	DLC1	P31749	AKT1	S666	R665H	665	Missense	proximal	-1	no	9.369	9.325	EPSD	TCGA;COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	Q96QB1	DLC1	P31749	AKT1	S673	S679C	679	Missense	distal	6	no	11.401	11.198	EPSD	TCGA;COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	Q96QB1	DLC1	P31749	AKT1	S673	R670P	670	Missense	distal	-3	no	11.401	4.761	EPSD	TCGA;ICGC;COSMIC	7.780	Loss
AGC_Akt_AKT1_ST	Q96QB1	DLC1	P31749	AKT1	S673	K677N	677	Missense	distal	4	no	11.401	11.533	EPSD	TCGA;COSMIC	7.780	Up-regulation
AGC_Akt_AKT1_ST	Q96QB1	DLC1	P31749	AKT1	S673	H680N	680	Missense	distal	7	no	11.401	11.430	EPSD	TCGA;COSMIC	7.780	Up-regulation
AGC_Akt_AKT1_ST	Q96QB1	DLC1	P31749	AKT1	S673	K675R	675	Missense	proximal	2	no	11.401	11.212	EPSD	TCGA	7.780	Down-regulation
AGC_Akt_AKT1_ST	Q96QB1	DLC1	P31749	AKT1	S733	V734I	734	Missense	proximal	1	no	10.316	10.069	EPSD	TCGA;COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	Q96QB1	DLC1	P31749	AKT1	S735	T738S	738	Missense	distal	3	no	16.477	16.478	PhosphoSitePlus;EPSD	TCGA;COSMIC	7.780	Up-regulation
AGC_Akt_AKT1_ST	Q96QB1	DLC1	P31749	AKT1	S735	V734I	734	Missense	proximal	-1	no	16.477	16.462	PhosphoSitePlus;EPSD	TCGA;COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	Q96QB1	DLC1	P31749	AKT1	S737	T738S	738	Missense	proximal	1	no	10.749	10.556	EPSD	TCGA;COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	Q96QB1	DLC1	P31749	AKT1	S737	V734I	734	Missense	distal	-3	no	10.749	10.533	EPSD	TCGA;COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	Q96QB1	DLC1	P31749	AKT1	S764	A767V	767	Missense	distal	3	no	12.778	12.746	EPSD	TCGA;COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	Q96QB1	DLC1	P31749	AKT1	S764	T760M	760	Missense	distal	-4	no	12.778	11.812	EPSD	TCGA;COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	Q96QB1	DLC1	P31749	AKT1	S764	R771W	771	Missense	distal	7	no	12.778	12.680	EPSD	TCGA;GDSC;CCLE	7.780	Down-regulation
AGC_Akt_AKT1_ST	Q96QB1	DLC1	P31749	AKT1	S764	P758L	758	Missense	distal	-6	no	12.778	12.791	EPSD	TCGA;COSMIC	7.780	Up-regulation
AGC_Akt_AKT1_ST	Q96QB1	DLC1	P31749	AKT1	S764	S764R	764	Missense	central	0	yes	12.778	0.000	EPSD	TCGA;COSMIC	7.780	Loss
AGC_Akt_AKT1_ST	Q96QB1	DLC1	P31749	AKT1	S766	A767V	767	Missense	proximal	1	no	15.353	15.425	EPSD;PhosphoSitePlus	TCGA;COSMIC	7.780	Up-regulation
AGC_Akt_AKT1_ST	Q96QB1	DLC1	P31749	AKT1	S766	T760M	760	Missense	distal	-6	no	15.353	15.260	EPSD;PhosphoSitePlus	TCGA;COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	Q96QB1	DLC1	P31749	AKT1	S766	R771W	771	Missense	distal	5	no	15.353	15.259	EPSD;PhosphoSitePlus	TCGA;GDSC;CCLE	7.780	Down-regulation
AGC_Akt_AKT1_ST	Q96QB1	DLC1	P31749	AKT1	S766	S764R	764	Missense	proximal	-2	no	15.353	15.165	EPSD;PhosphoSitePlus	TCGA;COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	Q96QB1	DLC1	P31749	AKT1	S830	S830L	830	Missense	central	0	yes	7.909	0.000	EPSD	TCGA;ICGC;COSMIC	7.780	Loss
AGC_Akt_AKT1_ST	Q96QB1	DLC1	P31749	AKT1	S830	G834S	834	Missense	distal	4	no	7.909	7.735	EPSD	TCGA;COSMIC	7.780	Loss
AGC_Akt_AKT1_ST	Q96QB1	DLC1	P31749	AKT1	S830	N837S	837	Missense	distal	7	no	7.909	7.944	EPSD	TCGA;COSMIC	7.780	Up-regulation
AGC_Akt_AKT1_ST	Q96QB1	DLC1	P31749	AKT1	S842	H848Y	848	Missense	distal	6	no	9.815	9.847	EPSD	TCGA;COSMIC	7.780	Up-regulation
AGC_Akt_AKT1_ST	Q96QB1	DLC1	P31749	AKT1	S842	P846H	846	Missense	distal	4	no	9.815	9.855	EPSD	TCGA;COSMIC	7.780	Up-regulation
AGC_Akt_AKT1_ST	Q96QB1	DLC1	P31749	AKT1	S842	N837S	837	Missense	distal	-5	no	9.815	9.829	EPSD	TCGA;COSMIC	7.780	Up-regulation
AGC_Akt_AKT1_ST	Q96QB1	DLC1	P31749	AKT1	S856	N855K	855	Missense	proximal	-1	no	11.907	11.932	EPSD	TCGA;COSMIC	7.780	Up-regulation
AGC_Akt_AKT1_ST	Q96QB1	DLC1	P31749	AKT1	S856	D858N	858	Missense	proximal	2	no	11.907	12.237	EPSD	TCGA;COSMIC	7.780	Up-regulation
AGC_Akt_AKT1_ST	Q96QB1	DLC1	P31749	AKT1	S856	K861N	861	Missense	distal	5	no	11.907	11.872	EPSD	TCGA;COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	Q96QB1	DLC1	P31749	AKT1	S857	N855K	855	Missense	proximal	-2	no	9.035	9.972	EPSD	TCGA;COSMIC	7.780	Up-regulation
AGC_Akt_AKT1_ST	Q96QB1	DLC1	P31749	AKT1	S857	D858N	858	Missense	proximal	1	no	9.035	9.160	EPSD	TCGA;COSMIC	7.780	Up-regulation
AGC_Akt_AKT1_ST	Q96QB1	DLC1	P31749	AKT1	S857	K861N	861	Missense	distal	4	no	9.035	9.167	EPSD	TCGA;COSMIC	7.780	Up-regulation
AGC_Akt_AKT1_ST	Q96QB1	DLC1	P31749	AKT1	S868	R866C	866	Missense	proximal	-2	no	12.939	11.475	EPSD	TCGA;COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	Q96QB1	DLC1	P31749	AKT1	S868	R866P	866	Missense	proximal	-2	no	12.939	12.303	EPSD	TCGA;COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	Q96QB1	DLC1	P31749	AKT1	S868	K861N	861	Missense	distal	-7	no	12.939	12.782	EPSD	TCGA;COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	Q96QB1	DLC1	P31749	AKT1	S869	R866C	866	Missense	distal	-3	no	13.477	7.304	EPSD	TCGA;COSMIC	7.780	Loss
AGC_Akt_AKT1_ST	Q96QB1	DLC1	P31749	AKT1	S869	R866P	866	Missense	distal	-3	no	13.477	6.838	EPSD	TCGA;COSMIC	7.780	Loss
AGC_Akt_AKT1_ST	Q96QB1	DLC1	P31749	AKT1	S870	R866C	866	Missense	distal	-4	no	10.064	8.386	EPSD	TCGA;COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	Q96QB1	DLC1	P31749	AKT1	S870	R866P	866	Missense	distal	-4	no	10.064	9.242	EPSD	TCGA;COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	Q96QB1	DLC1	P31749	AKT1	S986	R984S	984	Missense	proximal	-2	no	12.650	12.838	EPSD	TCGA;ICGC;COSMIC	7.780	Up-regulation
AGC_Akt_AKT1_ST	Q96QB1	DLC1	P31749	AKT1	S986	G987V	987	Missense	proximal	1	no	12.650	12.954	EPSD	TCGA;ICGC;COSMIC	7.780	Up-regulation
AGC_Akt_AKT1_ST	Q96QB1	DLC1	P31749	AKT1	S986	A990S	990	Missense	distal	4	no	12.650	12.526	EPSD	TCGA;COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	Q96QB1	DLC1	P31749	AKT1	S1004	H998R	998	Missense	distal	-6	no	15.281	15.399	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	7.780	Up-regulation
AGC_Akt_AKT1_ST	Q96QB1	DLC1	P31749	AKT1	S1015	L1018P	1018	Missense	distal	3	no	7.777	7.793	EPSD	TCGA;ICGC;COSMIC	7.780	Gain
AGC_Akt_AKT1_ST	Q96QB1	DLC1	P31749	AKT1	S1244	E1242K	1242	Missense	proximal	-2	no	12.859	13.518	EPSD	TCGA;ICGC;COSMIC	7.780	Up-regulation
AGC_Akt_AKT1_ST	Q96QB1	DLC1	P31749	AKT1	S1244	S1244F	1244	Missense	central	0	yes	12.859	0.000	EPSD	TCGA;COSMIC	7.780	Loss
AGC_Akt_AKT1_ST	Q96QB1	DLC1	P31749	AKT1	S1254	K1261N	1261	Missense	distal	7	no	11.719	11.684	EPSD	TCGA;COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	Q96QB1	DLC1	P31749	AKT1	T1298	N1295H	1295	Missense	distal	-3	no	6.332	9.109	EPSD	TCGA;COSMIC	7.780	Gain
AGC_Akt_AKT1_ST	Q96QB1	DLC1	P31749	AKT1	S1516	S1514F	1514	Missense	proximal	-2	no	9.256	8.390	EPSD	TCGA;COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	Q96QB1	DLC1	P31749	AKT1	S1516	K1523E	1523	Missense	distal	7	no	9.256	9.223	EPSD	TCGA;COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	Q96QB1	DLC1	P31749	AKT1	S1516	K1510T	1510	Missense	distal	-6	no	9.256	9.267	EPSD	TCGA;COSMIC	7.780	Up-regulation
AGC_Akt_AKT1_ST	P26373	RPL13	P31749	AKT1	S97	P100T	100	Missense	distal	3	no	9.562	9.643	EPSD	TCGA;ICGC;COSMIC	7.780	Up-regulation
AGC_Akt_AKT1_ST	P26373	RPL13	P31749	AKT1	S97	R101K	101	Missense	distal	4	no	9.562	9.529	EPSD	TCGA;ICGC;COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	P26373	RPL13	P31749	AKT1	S97	S97Y	97	Missense	central	0	yes	9.562	0.000	EPSD	TCGA;ICGC;COSMIC	7.780	Loss
AGC_Akt_AKT1_ST	P26373	RPL13	P31749	AKT1	S106	P100T	100	Missense	distal	-6	no	15.515	15.609	PhosphoSitePlus	TCGA;ICGC;COSMIC	7.780	Up-regulation
AGC_Akt_AKT1_ST	P26373	RPL13	P31749	AKT1	S106	R101K	101	Missense	distal	-5	no	15.515	13.117	PhosphoSitePlus	TCGA;ICGC;COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	P26373	RPL13	P31749	AKT1	S106	S109F	109	Missense	distal	3	no	15.515	15.416	PhosphoSitePlus	TCGA;ICGC;COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	P26373	RPL13	P31749	AKT1	S132	S132L	132	Missense	central	0	yes	11.763	0.000	EPSD	TCGA;ICGC;COSMIC	7.780	Loss
AGC_Akt_AKT1_ST	P55072	VCP	P31749	AKT1	S13	D11N	11	Missense	proximal	-2	no	7.272	7.979	EPSD	TCGA;ICGC;COSMIC	7.780	Gain
AGC_Akt_AKT1_ST	P55072	VCP	P31749	AKT1	T56	K62N	62	Missense	distal	6	no	10.933	10.855	EPSD	TCGA;ICGC;COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	P55072	VCP	P31749	AKT1	T316	A310T	310	Missense	distal	-6	no	12.127	12.212	EPSD	TCGA;ICGC;COSMIC	7.780	Up-regulation
AGC_Akt_AKT1_ST	P55072	VCP	P31749	AKT1	T316	R323H	323	Missense	distal	7	no	12.127	12.055	EPSD	TCGA;ICGC;COSMIC;GDSC;CCLE	7.780	Down-regulation
AGC_Akt_AKT1_ST	P55072	VCP	P31749	AKT1	S326	S326L	326	Missense	central	0	yes	11.518	0.000	EPSD	TCGA;ICGC;COSMIC	7.780	Loss
AGC_Akt_AKT1_ST	P55072	VCP	P31749	AKT1	S326	R323H	323	Missense	distal	-3	no	11.518	6.820	EPSD	TCGA;ICGC;COSMIC;GDSC;CCLE	7.780	Loss
AGC_Akt_AKT1_ST	P55072	VCP	P31749	AKT1	S352	R359Q	359	Missense	distal	7	no	12.816	12.760	PhosphoSitePlus;EPSD	TCGA;ICGC;COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	P55072	VCP	P31749	AKT1	S352	S352N	352	Missense	central	0	yes	12.816	0.000	PhosphoSitePlus;EPSD	TCGA;ICGC	7.780	Loss
AGC_Akt_AKT1_ST	P55072	VCP	P31749	AKT1	S352	S352I	352	Missense	central	0	yes	12.816	0.000	PhosphoSitePlus;EPSD	TCGA;ICGC	7.780	Loss
AGC_Akt_AKT1_ST	P55072	VCP	P31749	AKT1	S705	E712K	712	Missense	distal	7	no	8.293	8.327	EPSD	TCGA;ICGC;COSMIC	7.780	Up-regulation
AGC_Akt_AKT1_ST	P55072	VCP	P31749	AKT1	S705	E712D	712	Missense	distal	7	no	8.293	8.250	EPSD	TCGA;ICGC	7.780	Down-regulation
AGC_Akt_AKT1_ST	P55072	VCP	P31749	AKT1	S705	E704K	704	Missense	proximal	-1	no	8.293	8.314	EPSD	TCGA;ICGC;COSMIC	7.780	Up-regulation
AGC_Akt_AKT1_ST	P55072	VCP	P31749	AKT1	S705	A698T	698	Missense	distal	-7	no	8.293	8.493	EPSD	TCGA;ICGC;GDSC	7.780	Up-regulation
AGC_Akt_AKT1_ST	P55072	VCP	P31749	AKT1	S705	R709Q	709	Missense	distal	4	no	8.293	8.416	EPSD	TCGA;ICGC;GDSC;CCLE	7.780	Up-regulation
AGC_Akt_AKT1_ST	P55072	VCP	P31749	AKT1	S705	R700C	700	Missense	distal	-5	no	8.293	4.216	EPSD	TCGA;ICGC;COSMIC	7.780	Loss
AGC_Akt_AKT1_ST	P55072	VCP	P31749	AKT1	S718	S718L	718	Missense	central	0	yes	8.543	0.000	EPSD	TCGA;ICGC;COSMIC	7.780	Loss
AGC_Akt_AKT1_ST	P55072	VCP	P31749	AKT1	S718	E712K	712	Missense	distal	-6	no	8.543	8.610	EPSD	TCGA;ICGC;COSMIC	7.780	Up-regulation
AGC_Akt_AKT1_ST	P55072	VCP	P31749	AKT1	S718	T715I	715	Missense	distal	-3	no	8.543	8.484	EPSD	TCGA;ICGC;COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	P55072	VCP	P31749	AKT1	S718	E712D	712	Missense	distal	-6	no	8.543	8.471	EPSD	TCGA;ICGC	7.780	Down-regulation
AGC_Akt_AKT1_ST	P55072	VCP	P31749	AKT1	S746	A743T	743	Missense	distal	-3	no	11.046	10.327	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	P55072	VCP	P31749	AKT1	S746	R745H	745	Missense	proximal	-1	no	11.046	11.001	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	P55072	VCP	P31749	AKT1	S746	R741C	741	Missense	distal	-5	no	11.046	6.969	EPSD;PhosphoSitePlus	TCGA;ICGC	7.780	Loss
AGC_Akt_AKT1_ST	P55072	VCP	P31749	AKT1	S748	A743T	743	Missense	distal	-5	no	12.791	12.916	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	7.780	Up-regulation
AGC_Akt_AKT1_ST	P55072	VCP	P31749	AKT1	S748	R745H	745	Missense	distal	-3	no	12.791	8.093	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	P55072	VCP	P31749	AKT1	S748	R741C	741	Missense	distal	-7	no	12.791	12.312	EPSD;PhosphoSitePlus	TCGA;ICGC	7.780	Down-regulation
AGC_Akt_AKT1_ST	P55072	VCP	P31749	AKT1	S775	R772G	772	Missense	distal	-3	no	9.150	2.394	EPSD	TCGA;ICGC;COSMIC	7.780	Loss
AGC_Akt_AKT1_ST	Q92793	CREBBP	P31749	AKT1	S78	G79S	79	Missense	proximal	1	no	10.808	11.113	EPSD	TCGA;ICGC;COSMIC	7.780	Up-regulation
AGC_Akt_AKT1_ST	Q92793	CREBBP	P31749	AKT1	S78	S71L	71	Missense	distal	-7	no	10.808	10.574	EPSD	TCGA;ICGC;COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	Q92793	CREBBP	P31749	AKT1	S80	G79S	79	Missense	proximal	-1	no	9.208	9.238	EPSD	TCGA;ICGC;COSMIC	7.780	Up-regulation
AGC_Akt_AKT1_ST	Q92793	CREBBP	P31749	AKT1	S381	P383L	383	Missense	proximal	2	no	11.446	11.237	EPSD	TCGA;ICGC;COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	Q92793	CREBBP	P31749	AKT1	S381	P383R	383	Missense	proximal	2	no	11.446	11.611	EPSD	TCGA;ICGC;COSMIC	7.780	Up-regulation
AGC_Akt_AKT1_ST	Q92793	CREBBP	P31749	AKT1	S745	M739I	739	Missense	distal	-6	no	12.849	12.791	EPSD	TCGA	7.780	Down-regulation
AGC_Akt_AKT1_ST	Q92793	CREBBP	P31749	AKT1	S745	P746S	746	Missense	proximal	1	no	12.849	13.004	EPSD	TCGA;COSMIC	7.780	Up-regulation
AGC_Akt_AKT1_ST	Q92793	CREBBP	P31749	AKT1	S745	V751I	751	Missense	distal	6	no	12.849	12.798	EPSD	TCGA;COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	Q92793	CREBBP	P31749	AKT1	S745	R742C	742	Missense	distal	-3	no	12.849	6.676	EPSD	TCGA;COSMIC	7.780	Loss
AGC_Akt_AKT1_ST	Q92793	CREBBP	P31749	AKT1	S1108	P1110R	1110	Missense	proximal	2	no	9.863	10.027	EPSD	TCGA;COSMIC	7.780	Up-regulation
AGC_Akt_AKT1_ST	Q92793	CREBBP	P31749	AKT1	T1274	E1278K	1278	Missense	distal	4	no	8.300	8.199	EPSD	TCGA;COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	Q92793	CREBBP	P31749	AKT1	T1274	P1279L	1279	Missense	distal	5	no	8.300	8.287	EPSD	TCGA;COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	Q92793	CREBBP	P31749	AKT1	S1568	T1575N	1575	Missense	distal	7	no	11.882	11.837	EPSD	TCGA	7.780	Down-regulation
AGC_Akt_AKT1_ST	Q92793	CREBBP	P31749	AKT1	S1767	R1768C	1768	Missense	proximal	1	no	7.818	7.290	EPSD	TCGA;COSMIC	7.780	Loss
AGC_Akt_AKT1_ST	Q92793	CREBBP	P31749	AKT1	S1767	S1767L	1767	Missense	central	0	yes	7.818	0.000	EPSD	TCGA;COSMIC	7.780	Loss
AGC_Akt_AKT1_ST	Q92793	CREBBP	P31749	AKT1	S1767	E1766K	1766	Missense	proximal	-1	no	7.818	7.839	EPSD	TCGA;COSMIC	7.780	Up-regulation
AGC_Akt_AKT1_ST	Q92793	CREBBP	P31749	AKT1	S1771	R1768C	1768	Missense	distal	-3	no	12.661	6.488	EPSD	TCGA;COSMIC	7.780	Loss
AGC_Akt_AKT1_ST	Q92793	CREBBP	P31749	AKT1	S1771	S1767L	1767	Missense	distal	-4	no	12.661	11.537	EPSD	TCGA;COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	Q92793	CREBBP	P31749	AKT1	S1771	E1766K	1766	Missense	distal	-5	no	12.661	14.359	EPSD	TCGA;COSMIC	7.780	Up-regulation
AGC_Akt_AKT1_ST	Q92793	CREBBP	P31749	AKT1	S1771	S1778L	1778	Missense	distal	7	no	12.661	12.595	EPSD	TCGA;COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	Q92793	CREBBP	P31749	AKT1	S1791	R1786H	1786	Missense	distal	-5	no	10.203	7.109	EPSD	TCGA;COSMIC	7.780	Loss
AGC_Akt_AKT1_ST	Q92793	CREBBP	P31749	AKT1	S1791	R1786C	1786	Missense	distal	-5	no	10.203	6.127	EPSD	TCGA;COSMIC	7.780	Loss
AGC_Akt_AKT1_ST	Q92793	CREBBP	P31749	AKT1	T1871	R1875L	1875	Missense	distal	4	no	15.103	15.280	PhosphoSitePlus	TCGA;COSMIC	7.780	Up-regulation
AGC_Akt_AKT1_ST	Q92793	CREBBP	P31749	AKT1	T1931	V1924M	1924	Missense	distal	-7	no	8.972	9.034	EPSD	TCGA;COSMIC	7.780	Up-regulation
AGC_Akt_AKT1_ST	Q92793	CREBBP	P31749	AKT1	T1931	A1925G	1925	Missense	distal	-6	no	8.972	8.948	EPSD	TCGA;COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	Q92793	CREBBP	P31749	AKT1	T1990	Q1994H	1994	Missense	distal	4	no	8.260	8.322	EPSD	TCGA;COSMIC	7.780	Up-regulation
AGC_Akt_AKT1_ST	Q92793	CREBBP	P31749	AKT1	T1990	R1985C	1985	Missense	distal	-5	no	8.260	4.183	EPSD	TCGA;COSMIC	7.780	Loss
AGC_Akt_AKT1_ST	Q92793	CREBBP	P31749	AKT1	T1990	A1996T	1996	Missense	distal	6	no	8.260	8.363	EPSD	TCGA;COSMIC	7.780	Up-regulation
AGC_Akt_AKT1_ST	Q92793	CREBBP	P31749	AKT1	S2063	A2066T	2066	Missense	distal	3	no	12.488	12.545	EPSD	TCGA;COSMIC	7.780	Up-regulation
AGC_Akt_AKT1_ST	Q92793	CREBBP	P31749	AKT1	S2065	A2066T	2066	Missense	proximal	1	no	10.199	10.466	EPSD	TCGA;COSMIC	7.780	Up-regulation
AGC_Akt_AKT1_ST	Q92793	CREBBP	P31749	AKT1	S2065	R2072W	2072	Missense	distal	7	no	10.199	10.101	EPSD	TCGA;COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	Q92793	CREBBP	P31749	AKT1	S2065	R2072Q	2072	Missense	distal	7	no	10.199	10.144	EPSD	TCGA;COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	Q92793	CREBBP	P31749	AKT1	S2356	R2353L	2353	Missense	distal	-3	no	11.114	4.120	EPSD	TCGA;COSMIC	7.780	Loss
AGC_Akt_AKT1_ST	Q92793	CREBBP	P31749	AKT1	S2356	S2356F	2356	Missense	central	0	yes	11.114	0.000	EPSD	TCGA;COSMIC	7.780	Loss
AGC_Akt_AKT1_ST	Q92793	CREBBP	P31749	AKT1	S2356	S2351F	2351	Missense	distal	-5	no	11.114	12.062	EPSD	TCGA;COSMIC	7.780	Up-regulation
AGC_Akt_AKT1_ST	Q92793	CREBBP	P31749	AKT1	S2422	D2429N	2429	Missense	distal	7	no	11.531	11.573	EPSD	TCGA;COSMIC	7.780	Up-regulation
AGC_Akt_AKT1_ST	P08670	VIM	P31749	AKT1	S7	S8L	8	Missense	proximal	1	no	12.841	12.939	EPSD	TCGA;ICGC;COSMIC	7.780	Up-regulation
AGC_Akt_AKT1_ST	P08670	VIM	P31749	AKT1	S9	S8L	8	Missense	proximal	-1	no	10.359	10.331	EPSD	TCGA;ICGC;COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	P08670	VIM	P31749	AKT1	S9	F15L	15	Missense	distal	6	no	10.359	10.375	EPSD	TCGA;ICGC;COSMIC	7.780	Up-regulation
AGC_Akt_AKT1_ST	P08670	VIM	P31749	AKT1	S9	F15V	15	Missense	distal	6	no	10.359	10.365	EPSD	TCGA;ICGC	7.780	Up-regulation
AGC_Akt_AKT1_ST	P08670	VIM	P31749	AKT1	S26	S22I	22	Missense	distal	-4	no	11.796	10.414	EPSD	TCGA;ICGC;COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	P08670	VIM	P31749	AKT1	S26	T33M	33	Missense	distal	7	no	11.796	11.727	EPSD	TCGA;ICGC;COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	P08670	VIM	P31749	AKT1	S39	T33M	33	Missense	distal	-6	no	11.642	11.549	PhosphoSitePlus	TCGA;ICGC;COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	P08670	VIM	P31749	AKT1	T48	R50H	50	Missense	proximal	2	no	9.132	8.771	EPSD	TCGA;ICGC;COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	P08670	VIM	P31749	AKT1	S55	R50H	50	Missense	distal	-5	no	8.851	5.756	EPSD	TCGA;ICGC;COSMIC	7.780	Loss
AGC_Akt_AKT1_ST	P08670	VIM	P31749	AKT1	S55	P57L	57	Missense	proximal	2	no	8.851	8.642	EPSD	TCGA;ICGC;COSMIC;CCLE	7.780	Down-regulation
AGC_Akt_AKT1_ST	P08670	VIM	P31749	AKT1	S55	P57R	57	Missense	proximal	2	no	8.851	9.015	EPSD	TCGA;ICGC;COSMIC	7.780	Up-regulation
AGC_Akt_AKT1_ST	P08670	VIM	P31749	AKT1	S72	R71W	71	Missense	proximal	-1	no	10.158	10.097	EPSD	TCGA;ICGC;COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	P08670	VIM	P31749	AKT1	S226	E221K	221	Missense	distal	-5	no	6.859	8.557	EPSD	TCGA;ICGC;COSMIC	7.780	Gain
AGC_Akt_AKT1_ST	P08670	VIM	P31749	AKT1	S278	S278R	278	Missense	central	0	yes	8.023	0.000	EPSD	TCGA;ICGC;COSMIC	7.780	Loss
AGC_Akt_AKT1_ST	P08670	VIM	P31749	AKT1	S278	N283D	283	Missense	distal	5	no	8.023	7.983	EPSD	TCGA;ICGC;COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	P08670	VIM	P31749	AKT1	S325	A332S	332	Missense	distal	7	no	7.881	7.932	EPSD	TCGA;ICGC;COSMIC	7.780	Up-regulation
AGC_Akt_AKT1_ST	P08670	VIM	P31749	AKT1	S325	R320Q	320	Missense	distal	-5	no	7.881	3.654	EPSD	TCGA;ICGC;COSMIC	7.780	Loss
AGC_Akt_AKT1_ST	P08670	VIM	P31749	AKT1	S325	L326F	326	Missense	proximal	1	no	7.881	7.800	EPSD	TCGA;ICGC;COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	P08670	VIM	P31749	AKT1	S325	S325F	325	Missense	central	0	yes	7.881	0.000	EPSD	TCGA;ICGC;COSMIC	7.780	Loss
AGC_Akt_AKT1_ST	P08670	VIM	P31749	AKT1	S325	Y319C	319	Missense	distal	-6	no	7.881	7.794	EPSD	TCGA;ICGC;COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	P08670	VIM	P31749	AKT1	S325	S325P	325	Missense	central	0	yes	7.881	0.000	EPSD	TCGA;ICGC;COSMIC;CCLE	7.780	Loss
AGC_Akt_AKT1_ST	Q7L5N1	COPS6	P31749	AKT1	S60	S60F	60	Missense	central	0	yes	9.584	0.000	PhosphoSitePlus	TCGA;ICGC;COSMIC	7.780	Loss
AGC_Akt_AKT1_ST	Q7L5N1	COPS6	P31749	AKT1	S60	S60P	60	Missense	central	0	yes	9.584	0.000	PhosphoSitePlus	TCGA;ICGC	7.780	Loss
AGC_Akt_AKT1_ST	Q16763	UBE2S	P31749	AKT1	T152	A158V	158	Missense	distal	6	no	13.745	13.713	PhosphoSitePlus	TCGA;ICGC	7.780	Down-regulation
AGC_Akt_AKT1_ST	Q96F86	EDC3	P31749	AKT1	S109	Q115E	115	Missense	distal	6	no	8.092	8.106	EPSD	TCGA;ICGC;COSMIC	7.780	Up-regulation
AGC_Akt_AKT1_ST	Q96F86	EDC3	P31749	AKT1	S109	Q115L	115	Missense	distal	6	no	8.092	8.061	EPSD	TCGA;ICGC;COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	Q96F86	EDC3	P31749	AKT1	S110	Q115E	115	Missense	distal	5	no	7.836	7.847	EPSD	TCGA;ICGC;COSMIC	7.780	Up-regulation
AGC_Akt_AKT1_ST	Q96F86	EDC3	P31749	AKT1	S110	Q115L	115	Missense	distal	5	no	7.836	7.813	EPSD	TCGA;ICGC;COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	Q96F86	EDC3	P31749	AKT1	S125	D122A	122	Missense	distal	-3	no	8.609	8.257	EPSD	TCGA;ICGC;COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	Q96F86	EDC3	P31749	AKT1	S125	Q126H	126	Missense	proximal	1	no	8.609	8.581	EPSD	TCGA;ICGC;COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	Q96F86	EDC3	P31749	AKT1	S125	K124N	124	Missense	proximal	-1	no	8.609	8.584	EPSD	TCGA;ICGC;COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	Q96F86	EDC3	P31749	AKT1	S125	S131F	131	Missense	distal	6	no	8.609	8.489	EPSD	TCGA;ICGC;COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	Q96F86	EDC3	P31749	AKT1	S161	H168Y	168	Missense	distal	7	no	16.373	16.394	PhosphoSitePlus	TCGA;ICGC	7.780	Up-regulation
AGC_Akt_AKT1_ST	Q96F86	EDC3	P31749	AKT1	S161	S161F	161	Missense	central	0	yes	16.373	0.000	PhosphoSitePlus	TCGA;ICGC;COSMIC	7.780	Loss
AGC_Akt_AKT1_ST	Q96F86	EDC3	P31749	AKT1	S163	H168Y	168	Missense	distal	5	no	8.191	8.214	EPSD	TCGA;ICGC	7.780	Up-regulation
AGC_Akt_AKT1_ST	Q96F86	EDC3	P31749	AKT1	S163	S161F	161	Missense	proximal	-2	no	8.191	7.324	EPSD	TCGA;ICGC;COSMIC	7.780	Loss
AGC_Akt_AKT1_ST	Q96F86	EDC3	P31749	AKT1	S233	R232H	232	Missense	proximal	-1	no	11.116	11.071	EPSD	TCGA;ICGC;COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	Q96F86	EDC3	P31749	AKT1	S233	P237R	237	Missense	distal	4	no	11.116	10.971	EPSD	TCGA;ICGC;COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	Q96F86	EDC3	P31749	AKT1	T308	R303Q	303	Missense	distal	-5	no	8.418	4.191	EPSD	TCGA;ICGC;COSMIC	7.780	Loss
AGC_Akt_AKT1_ST	P14598	NCF1	P31749	AKT1	T45	Y48C	48	Missense	distal	3	no	11.183	11.074	EPSD	TCGA;ICGC;COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	P14598	NCF1	P31749	AKT1	T45	H51Q	51	Missense	distal	6	no	11.183	11.231	EPSD	TCGA;ICGC;COSMIC	7.780	Up-regulation
AGC_Akt_AKT1_ST	P14598	NCF1	P31749	AKT1	T45	E49K	49	Missense	distal	4	no	11.183	11.082	EPSD	TCGA;ICGC;COSMIC;GDSC	7.780	Down-regulation
AGC_Akt_AKT1_ST	P14598	NCF1	P31749	AKT1	T93	E96K	96	Missense	distal	3	no	12.081	12.125	EPSD	TCGA;ICGC;COSMIC	7.780	Up-regulation
AGC_Akt_AKT1_ST	P14598	NCF1	P31749	AKT1	T95	E96K	96	Missense	proximal	1	no	9.024	9.187	EPSD	TCGA;ICGC;COSMIC	7.780	Up-regulation
AGC_Akt_AKT1_ST	P14598	NCF1	P31749	AKT1	S328	F331S	331	Missense	distal	3	no	11.919	12.018	PhosphoSitePlus;EPSD	TCGA;ICGC;COSMIC	7.780	Up-regulation
AGC_Akt_AKT1_ST	P05455	SSB	P31749	AKT1	S94	L97P	97	Missense	distal	3	no	12.297	12.313	EPSD	TCGA;ICGC;COSMIC	7.780	Up-regulation
AGC_Akt_AKT1_ST	P20749	BCL3	P31749	AKT1	S367	P373L	373	Missense	distal	6	no	12.624	12.614	EPSD	TCGA;ICGC;COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	P20749	BCL3	P31749	AKT1	S369	P373L	373	Missense	distal	4	no	9.057	9.089	EPSD	TCGA;ICGC;COSMIC	7.780	Up-regulation
AGC_Akt_AKT1_ST	P20749	BCL3	P31749	AKT1	S382	E384K	384	Missense	proximal	2	no	9.514	9.719	EPSD	TCGA;ICGC;COSMIC	7.780	Up-regulation
AGC_Akt_AKT1_ST	P20749	BCL3	P31749	AKT1	S448	P451S	451	Missense	distal	3	no	9.964	10.046	EPSD	TCGA;ICGC;COSMIC	7.780	Up-regulation
AGC_Akt_AKT1_ST	P20749	BCL3	P31749	AKT1	S448	S448F	448	Missense	central	0	yes	9.964	0.000	EPSD	TCGA;ICGC;COSMIC	7.780	Loss
AGC_Akt_AKT1_ST	P20749	BCL3	P31749	AKT1	S448	R443Q	443	Missense	distal	-5	no	9.964	5.737	EPSD	TCGA;ICGC;COSMIC	7.780	Loss
AGC_Akt_AKT1_ST	Q5UE93	PIK3R6	P31749	AKT1	S22	A25V	25	Missense	distal	3	no	11.258	11.226	EPSD	TCGA;ICGC	7.780	Down-regulation
AGC_Akt_AKT1_ST	Q5UE93	PIK3R6	P31749	AKT1	T125	D118N	118	Missense	distal	-7	no	9.315	9.573	EPSD	TCGA;ICGC;COSMIC	7.780	Up-regulation
AGC_Akt_AKT1_ST	Q5UE93	PIK3R6	P31749	AKT1	T125	G131E	131	Missense	distal	6	no	9.315	9.361	EPSD	TCGA;COSMIC	7.780	Up-regulation
AGC_Akt_AKT1_ST	Q5UE93	PIK3R6	P31749	AKT1	T125	K124N	124	Missense	proximal	-1	no	9.315	9.291	EPSD	TCGA;ICGC	7.780	Down-regulation
AGC_Akt_AKT1_ST	Q5UE93	PIK3R6	P31749	AKT1	S217	R219G	219	Missense	proximal	2	no	9.559	9.399	EPSD	TCGA;ICGC;COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	Q5UE93	PIK3R6	P31749	AKT1	S217	R220C	220	Missense	distal	3	no	9.559	9.398	EPSD	TCGA;ICGC;COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	Q5UE93	PIK3R6	P31749	AKT1	S217	R220H	220	Missense	distal	3	no	9.559	9.475	EPSD	TCGA;ICGC;COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	Q5UE93	PIK3R6	P31749	AKT1	S217	S217N	217	Missense	central	0	yes	9.559	0.000	EPSD	TCGA;ICGC	7.780	Loss
AGC_Akt_AKT1_ST	Q5UE93	PIK3R6	P31749	AKT1	S308	R311C	311	Missense	distal	3	no	10.929	10.769	EPSD	TCGA;ICGC;COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	Q5UE93	PIK3R6	P31749	AKT1	S308	L304I	304	Missense	distal	-4	no	10.929	10.671	EPSD	TCGA;ICGC;COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	Q5UE93	PIK3R6	P31749	AKT1	S401	P400H	400	Missense	proximal	-1	no	9.797	9.792	EPSD	TCGA;ICGC;COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	Q5UE93	PIK3R6	P31749	AKT1	T442	P449L	449	Missense	distal	7	no	8.819	8.811	EPSD	TCGA;ICGC;COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	Q5UE93	PIK3R6	P31749	AKT1	T442	H435R	435	Missense	distal	-7	no	8.819	9.121	EPSD	TCGA;ICGC;COSMIC;CCLE	7.780	Up-regulation
AGC_Akt_AKT1_ST	Q5UE93	PIK3R6	P31749	AKT1	T442	P449H	449	Missense	distal	7	no	8.819	8.814	EPSD	TCGA;ICGC	7.780	Down-regulation
AGC_Akt_AKT1_ST	Q5UE93	PIK3R6	P31749	AKT1	T442	K444Q	444	Missense	proximal	2	no	8.819	8.514	EPSD	TCGA;ICGC	7.780	Down-regulation
AGC_Akt_AKT1_ST	Q5UE93	PIK3R6	P31749	AKT1	T607	S600N	600	Missense	distal	-7	no	14.171	14.056	PhosphoSitePlus	TCGA;ICGC;COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	Q96J02	ITCH	P31749	AKT1	S10	Q7R	7	Missense	distal	-3	no	7.165	14.376	EPSD	TCGA;ICGC;COSMIC	7.780	Gain
AGC_Akt_AKT1_ST	Q96J02	ITCH	P31749	AKT1	T214	S210Y	210	Missense	distal	-4	no	8.773	7.913	EPSD	TCGA;ICGC;COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	Q96J02	ITCH	P31749	AKT1	T214	G220E	220	Missense	distal	6	no	8.773	8.819	EPSD	TCGA;ICGC;COSMIC	7.780	Up-regulation
AGC_Akt_AKT1_ST	Q96J02	ITCH	P31749	AKT1	T214	R209I	209	Missense	distal	-5	no	8.773	4.205	EPSD	TCGA;ICGC	7.780	Loss
AGC_Akt_AKT1_ST	Q96J02	ITCH	P31749	AKT1	T214	N219Y	219	Missense	distal	5	no	8.773	8.764	EPSD	TCGA;ICGC;COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	Q96J02	ITCH	P31749	AKT1	T218	E225K	225	Missense	distal	7	no	10.607	10.641	EPSD	TCGA;ICGC;COSMIC	7.780	Up-regulation
AGC_Akt_AKT1_ST	Q96J02	ITCH	P31749	AKT1	T218	G220E	220	Missense	proximal	2	no	10.607	10.750	EPSD	TCGA;ICGC;COSMIC	7.780	Up-regulation
AGC_Akt_AKT1_ST	Q96J02	ITCH	P31749	AKT1	T218	N219Y	219	Missense	proximal	1	no	10.607	10.688	EPSD	TCGA;ICGC;COSMIC	7.780	Up-regulation
AGC_Akt_AKT1_ST	Q96J02	ITCH	P31749	AKT1	S236	S240C	240	Missense	distal	4	no	11.109	11.454	EPSD	TCGA;ICGC;COSMIC	7.780	Up-regulation
AGC_Akt_AKT1_ST	Q96J02	ITCH	P31749	AKT1	S257	T263P	263	Missense	distal	6	no	8.345	8.231	PhosphoSitePlus	TCGA;ICGC	7.780	Down-regulation
AGC_Akt_AKT1_ST	Q96J02	ITCH	P31749	AKT1	S257	P253L	253	Missense	distal	-4	no	8.345	7.958	PhosphoSitePlus	TCGA;ICGC;COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	Q96J02	ITCH	P31749	AKT1	S257	P259S	259	Missense	proximal	2	no	8.345	8.682	PhosphoSitePlus	TCGA;ICGC;COSMIC	7.780	Up-regulation
AGC_Akt_AKT1_ST	Q96J02	ITCH	P31749	AKT1	S393	Y397C	397	Missense	distal	4	no	8.892	9.101	EPSD	TCGA;ICGC;COSMIC	7.780	Up-regulation
AGC_Akt_AKT1_ST	Q96J02	ITCH	P31749	AKT1	S393	S393F	393	Missense	central	0	yes	8.892	0.000	EPSD	TCGA;ICGC;COSMIC	7.780	Loss
AGC_Akt_AKT1_ST	Q96J02	ITCH	P31749	AKT1	S393	S393P	393	Missense	central	0	yes	8.892	0.000	EPSD	TCGA;ICGC;COSMIC	7.780	Loss
AGC_Akt_AKT1_ST	Q96J02	ITCH	P31749	AKT1	S450	D449N	449	Missense	proximal	-1	no	12.364	12.394	EPSD	TCGA;ICGC;COSMIC	7.780	Up-regulation
AGC_Akt_AKT1_ST	Q96J02	ITCH	P31749	AKT1	S450	D449Y	449	Missense	proximal	-1	no	12.364	12.386	EPSD	TCGA;ICGC	7.780	Up-regulation
AGC_Akt_AKT1_ST	Q96J02	ITCH	P31749	AKT1	T504	R510S	510	Missense	distal	6	no	12.659	12.660	EPSD	TCGA;ICGC;COSMIC	7.780	Up-regulation
AGC_Akt_AKT1_ST	Q96J02	ITCH	P31749	AKT1	T504	R510H	510	Missense	distal	6	no	12.659	12.540	EPSD	TCGA;ICGC;COSMIC;CCLE	7.780	Down-regulation
AGC_Akt_AKT1_ST	Q96J02	ITCH	P31749	AKT1	T505	R510S	510	Missense	distal	5	no	12.283	12.276	EPSD	TCGA;ICGC;COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	Q96J02	ITCH	P31749	AKT1	T505	R510H	510	Missense	distal	5	no	12.283	12.209	EPSD	TCGA;ICGC;COSMIC;CCLE	7.780	Down-regulation
AGC_Akt_AKT1_ST	P0DMV8	HSPA1A	P31749	AKT1	S631	E638K	638	Missense	distal	7	no	9.808	9.842	PhosphoSitePlus	TCGA;ICGC;COSMIC	7.780	Up-regulation
AGC_Akt_AKT1_ST	P0DMV8	HSPA1A	P31749	AKT1	S631	G632V	632	Missense	proximal	1	no	9.808	10.112	PhosphoSitePlus	TCGA;COSMIC	7.780	Up-regulation
AGC_Akt_AKT1_ST	P0DMV8	HSPA1A	P31749	AKT1	S633	E638K	638	Missense	distal	5	no	8.994	9.028	EPSD	TCGA;ICGC;COSMIC	7.780	Up-regulation
AGC_Akt_AKT1_ST	P0DMV8	HSPA1A	P31749	AKT1	S633	G632V	632	Missense	proximal	-1	no	8.994	8.988	EPSD	TCGA;COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	P0DMV8	HSPA1A	P31749	AKT1	S633	E639D	639	Missense	distal	6	no	8.994	8.903	EPSD	TCGA;COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	P29401	TKT	P31749	AKT1	S104	K102N	102	Missense	proximal	-2	no	11.957	11.020	EPSD	TCGA;COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	P29401	TKT	P31749	AKT1	S406	A404V	404	Missense	proximal	-2	no	8.598	7.860	EPSD	TCGA	7.780	Down-regulation
AGC_Akt_AKT1_ST	O15360	FANCA	P31749	AKT1	T323	F320L	320	Missense	distal	-3	no	10.569	9.169	EPSD	TCGA;ICGC;COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	O15360	FANCA	P31749	AKT1	S347	A349V	349	Missense	proximal	2	no	10.908	10.746	EPSD	TCGA;ICGC;COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	O15360	FANCA	P31749	AKT1	S391	S394C	394	Missense	distal	3	no	8.824	8.647	EPSD	TCGA;ICGC;COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	O15360	FANCA	P31749	AKT1	S581	A586T	586	Missense	distal	5	no	7.952	8.003	EPSD	TCGA;ICGC;COSMIC	7.780	Up-regulation
AGC_Akt_AKT1_ST	O15360	FANCA	P31749	AKT1	S581	R575S	575	Missense	distal	-6	no	7.952	7.917	EPSD	TCGA;ICGC;COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	O15360	FANCA	P31749	AKT1	S858	L864I	864	Missense	distal	6	no	8.747	8.686	EPSD	TCGA;ICGC;COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	O15360	FANCA	P31749	AKT1	S1149	D1147V	1147	Missense	proximal	-2	no	15.442	15.645	PhosphoSitePlus	TCGA;ICGC;COSMIC	7.780	Up-regulation
AGC_Akt_AKT1_ST	O15360	FANCA	P31749	AKT1	S1149	M1151I	1151	Missense	proximal	2	no	15.442	15.202	PhosphoSitePlus	TCGA;ICGC;COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	O15360	FANCA	P31749	AKT1	S1191	L1193R	1193	Missense	proximal	2	no	10.292	10.665	EPSD	TCGA	7.780	Up-regulation
AGC_Akt_AKT1_ST	O15360	FANCA	P31749	AKT1	S1191	R1186K	1186	Missense	distal	-5	no	10.292	7.895	EPSD	TCGA;ICGC;COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	O15360	FANCA	P31749	AKT1	S1191	P1192L	1192	Missense	proximal	1	no	10.292	10.546	EPSD	TCGA;ICGC;COSMIC	7.780	Up-regulation
AGC_Akt_AKT1_ST	Q9BPZ7	MAPKAP1	P31749	AKT1	S84	R89T	89	Missense	distal	5	no	11.019	11.012	EPSD	TCGA;ICGC;COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	Q9BPZ7	MAPKAP1	P31749	AKT1	S84	D77Y	77	Missense	distal	-7	no	11.019	11.184	EPSD	TCGA;ICGC;COSMIC	7.780	Up-regulation
AGC_Akt_AKT1_ST	Q9BPZ7	MAPKAP1	P31749	AKT1	S84	R81T	81	Missense	distal	-3	no	11.019	3.997	EPSD	TCGA;ICGC;COSMIC	7.780	Loss
AGC_Akt_AKT1_ST	Q9BPZ7	MAPKAP1	P31749	AKT1	S84	S84L	84	Missense	central	0	yes	11.019	0.000	EPSD	TCGA;ICGC;COSMIC	7.780	Loss
AGC_Akt_AKT1_ST	Q9BPZ7	MAPKAP1	P31749	AKT1	S84	R83C	83	Missense	proximal	-1	no	11.019	10.948	EPSD	TCGA;ICGC;COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	Q9BPZ7	MAPKAP1	P31749	AKT1	S84	R89I	89	Missense	distal	5	no	11.019	10.915	EPSD	TCGA;ICGC;COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	Q9BPZ7	MAPKAP1	P31749	AKT1	T86	R89T	89	Missense	distal	3	no	15.537	15.553	PhosphoSitePlus	TCGA;ICGC;COSMIC	7.780	Up-regulation
AGC_Akt_AKT1_ST	Q9BPZ7	MAPKAP1	P31749	AKT1	T86	R81T	81	Missense	distal	-5	no	15.537	11.808	PhosphoSitePlus	TCGA;ICGC;COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	Q9BPZ7	MAPKAP1	P31749	AKT1	T86	S84L	84	Missense	proximal	-2	no	15.537	14.681	PhosphoSitePlus	TCGA;ICGC;COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	Q9BPZ7	MAPKAP1	P31749	AKT1	T86	R83C	83	Missense	distal	-3	no	15.537	9.364	PhosphoSitePlus	TCGA;ICGC;COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	Q9BPZ7	MAPKAP1	P31749	AKT1	T86	R89I	89	Missense	distal	3	no	15.537	15.423	PhosphoSitePlus	TCGA;ICGC;COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	Q9BPZ7	MAPKAP1	P31749	AKT1	T194	D188N	188	Missense	distal	-6	no	8.316	8.388	EPSD	TCGA;ICGC;COSMIC	7.780	Up-regulation
AGC_Akt_AKT1_ST	Q9BPZ7	MAPKAP1	P31749	AKT1	T194	A201T	201	Missense	distal	7	no	8.316	8.377	EPSD	TCGA;COSMIC	7.780	Up-regulation
AGC_Akt_AKT1_ST	Q9BPZ7	MAPKAP1	P31749	AKT1	T194	T194I	194	Missense	central	0	yes	8.316	0.000	EPSD	TCGA;COSMIC	7.780	Loss
AGC_Akt_AKT1_ST	Q9BPZ7	MAPKAP1	P31749	AKT1	S260	E266K	266	Missense	distal	6	no	8.229	8.298	EPSD	TCGA;COSMIC	7.780	Up-regulation
AGC_Akt_AKT1_ST	Q9BPZ7	MAPKAP1	P31749	AKT1	S260	K256Q	256	Missense	distal	-4	no	8.229	7.621	EPSD	TCGA;ICGC;COSMIC	7.780	Loss
AGC_Akt_AKT1_ST	Q9BPZ7	MAPKAP1	P31749	AKT1	S315	R311Q	311	Missense	distal	-4	no	13.816	13.195	EPSD	TCGA;ICGC;COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	Q9BPZ7	MAPKAP1	P31749	AKT1	T509	R503T	503	Missense	distal	-6	no	8.207	8.204	EPSD	TCGA;COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	Q9BPZ7	MAPKAP1	P31749	AKT1	T509	T509M	509	Missense	central	0	yes	8.207	0.000	EPSD	TCGA;COSMIC	7.780	Loss
AGC_Akt_AKT1_ST	Q9BPZ7	MAPKAP1	P31749	AKT1	T509	R508H	508	Missense	proximal	-1	no	8.207	8.163	EPSD	TCGA;COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	Q9BPZ7	MAPKAP1	P31749	AKT1	T509	R508C	508	Missense	proximal	-1	no	8.207	8.137	EPSD	TCGA;COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	Q9BPZ7	MAPKAP1	P31749	AKT1	S510	R503T	503	Missense	distal	-7	no	15.046	15.041	EPSD	TCGA;COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	Q9BPZ7	MAPKAP1	P31749	AKT1	S510	T509M	509	Missense	proximal	-1	no	15.046	15.011	EPSD	TCGA;COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	Q9BPZ7	MAPKAP1	P31749	AKT1	S510	K517N	517	Missense	distal	7	no	15.046	15.011	EPSD	TCGA;COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	Q9BPZ7	MAPKAP1	P31749	AKT1	S510	R508H	508	Missense	proximal	-2	no	15.046	14.186	EPSD	TCGA;COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	Q9BPZ7	MAPKAP1	P31749	AKT1	S510	R508C	508	Missense	proximal	-2	no	15.046	13.582	EPSD	TCGA;COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	Q9BPZ7	MAPKAP1	P31749	AKT1	S512	T509M	509	Missense	distal	-3	no	12.910	12.426	EPSD	TCGA;COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	Q9BPZ7	MAPKAP1	P31749	AKT1	S512	K517N	517	Missense	distal	5	no	12.910	12.874	EPSD	TCGA;COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	Q9BPZ7	MAPKAP1	P31749	AKT1	S512	R508H	508	Missense	distal	-4	no	12.910	11.851	EPSD	TCGA;COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	Q9BPZ7	MAPKAP1	P31749	AKT1	S512	R508C	508	Missense	distal	-4	no	12.910	11.231	EPSD	TCGA;COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	P53602	MVD	P31749	AKT1	S156	R154W	154	Missense	proximal	-2	no	11.774	10.520	EPSD	TCGA;ICGC;GDSC	7.780	Down-regulation
AGC_Akt_AKT1_ST	P53602	MVD	P31749	AKT1	S158	R154W	154	Missense	distal	-4	no	8.711	7.161	EPSD	TCGA;ICGC;GDSC	7.780	Loss
AGC_Akt_AKT1_ST	P53602	MVD	P31749	AKT1	S211	G210D	210	Missense	proximal	-1	no	8.779	8.761	EPSD	TCGA;ICGC;COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	P53602	MVD	P31749	AKT1	S211	M215I	215	Missense	distal	4	no	8.779	8.877	EPSD	TCGA;ICGC;COSMIC;CCLE	7.780	Up-regulation
AGC_Akt_AKT1_ST	Q9BWT1	CDCA7	P31749	AKT1	T163	R158Q	158	Missense	distal	-5	no	14.466	10.239	PhosphoSitePlus	TCGA	7.780	Down-regulation
AGC_Akt_AKT1_ST	Q13185	CBX3	P31749	AKT1	S93	R91I	91	Missense	proximal	-2	no	8.448	7.396	EPSD	TCGA	7.780	Loss
AGC_Akt_AKT1_ST	Q13185	CBX3	P31749	AKT1	S93	G88D	88	Missense	distal	-5	no	8.448	8.467	EPSD	TCGA	7.780	Up-regulation
AGC_Akt_AKT1_ST	Q13185	CBX3	P31749	AKT1	S95	R91I	91	Missense	distal	-4	no	10.725	9.257	EPSD	TCGA	7.780	Down-regulation
AGC_Akt_AKT1_ST	Q13185	CBX3	P31749	AKT1	S95	G88D	88	Missense	distal	-7	no	10.725	10.539	EPSD	TCGA	7.780	Down-regulation
AGC_Akt_AKT1_ST	Q13185	CBX3	P31749	AKT1	S97	R91I	91	Missense	distal	-6	no	9.435	9.280	EPSD	TCGA	7.780	Down-regulation
AGC_Akt_AKT1_ST	Q13185	CBX3	P31749	AKT1	T173	E170D	170	Missense	distal	-3	no	7.179	7.800	EPSD	TCGA;ICGC;COSMIC	7.780	Gain
AGC_Akt_AKT1_ST	Q13185	CBX3	P31749	AKT1	S176	E170D	170	Missense	distal	-6	no	8.657	8.585	EPSD	TCGA;ICGC;COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	Q13185	CBX3	P31749	AKT1	S176	D180Y	180	Missense	distal	4	no	8.657	8.568	EPSD	TCGA;ICGC;COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	Q15942	ZYX	P31749	AKT1	S11	P17S	17	Missense	distal	6	no	8.020	8.113	EPSD	TCGA;ICGC;COSMIC	7.780	Up-regulation
AGC_Akt_AKT1_ST	Q15942	ZYX	P31749	AKT1	S11	S13L	13	Missense	proximal	2	no	8.020	7.474	EPSD	TCGA;ICGC;COSMIC	7.780	Loss
AGC_Akt_AKT1_ST	Q15942	ZYX	P31749	AKT1	S15	P17S	17	Missense	proximal	2	no	7.570	7.907	EPSD	TCGA;ICGC;COSMIC	7.780	Gain
AGC_Akt_AKT1_ST	Q15942	ZYX	P31749	AKT1	S143	D145V	145	Missense	proximal	2	no	10.254	10.315	EPSD	TCGA;ICGC;COSMIC	7.780	Up-regulation
AGC_Akt_AKT1_ST	Q15942	ZYX	P31749	AKT1	S143	D145N	145	Missense	proximal	2	no	10.254	10.584	EPSD	TCGA;ICGC;COSMIC	7.780	Up-regulation
AGC_Akt_AKT1_ST	Q15942	ZYX	P31749	AKT1	S170	R167L	167	Missense	distal	-3	no	11.209	4.215	EPSD	TCGA;ICGC;COSMIC	7.780	Loss
AGC_Akt_AKT1_ST	Q15942	ZYX	P31749	AKT1	S170	P163S	163	Missense	distal	-7	no	11.209	11.403	EPSD	TCGA;ICGC;COSMIC	7.780	Up-regulation
AGC_Akt_AKT1_ST	Q15942	ZYX	P31749	AKT1	S258	A261G	261	Missense	distal	3	no	8.170	8.137	EPSD	TCGA	7.780	Down-regulation
AGC_Akt_AKT1_ST	Q15942	ZYX	P31749	AKT1	S258	S259Y	259	Missense	proximal	1	no	8.170	8.163	EPSD	TCGA;ICGC;COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	Q15942	ZYX	P31749	AKT1	S258	P260L	260	Missense	proximal	2	no	8.170	7.961	EPSD	TCGA;ICGC;COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	Q15942	ZYX	P31749	AKT1	S258	S258A	258	Missense	central	0	yes	8.170	0.000	EPSD	TCGA;ICGC;COSMIC	7.780	Loss
AGC_Akt_AKT1_ST	Q15942	ZYX	P31749	AKT1	S303	E300K	300	Missense	distal	-3	no	5.916	7.968	EPSD	TCGA;ICGC;COSMIC	7.780	Gain
AGC_Akt_AKT1_ST	Q15942	ZYX	P31749	AKT1	T480	T480I	480	Missense	central	0	yes	7.876	0.000	EPSD	TCGA;ICGC;COSMIC	7.780	Loss
AGC_Akt_AKT1_ST	Q15942	ZYX	P31749	AKT1	T480	A474T	474	Missense	distal	-6	no	7.876	7.962	EPSD	TCGA;ICGC;COSMIC	7.780	Up-regulation
AGC_Akt_AKT1_ST	Q15942	ZYX	P31749	AKT1	T520	R517Q	517	Missense	distal	-3	no	9.532	2.321	EPSD	TCGA;ICGC;COSMIC	7.780	Loss
AGC_Akt_AKT1_ST	Q15942	ZYX	P31749	AKT1	T520	V524A	524	Missense	distal	4	no	9.532	9.476	EPSD	TCGA;ICGC;COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	Q15942	ZYX	P31749	AKT1	T520	A525T	525	Missense	distal	5	no	9.532	9.583	EPSD	TCGA;ICGC;COSMIC;GDSC;CCLE	7.780	Up-regulation
AGC_Akt_AKT1_ST	Q9UNN5	FAF1	P31749	AKT1	S270	R275Q	275	Missense	distal	5	no	13.035	12.985	EPSD	TCGA;ICGC;COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	Q9UNN5	FAF1	P31749	AKT1	T580	P581S	581	Missense	proximal	1	no	11.562	11.718	EPSD	TCGA;ICGC;COSMIC	7.780	Up-regulation
AGC_Akt_AKT1_ST	Q9UNN5	FAF1	P31749	AKT1	T580	R577W	577	Missense	distal	-3	no	11.562	2.622	EPSD	TCGA;ICGC	7.780	Loss
AGC_Akt_AKT1_ST	Q9UNN5	FAF1	P31749	AKT1	T580	F585L	585	Missense	distal	5	no	11.562	11.568	EPSD	TCGA;ICGC;COSMIC	7.780	Up-regulation
AGC_Akt_AKT1_ST	Q9UNN5	FAF1	P31749	AKT1	T580	S582N	582	Missense	proximal	2	no	11.562	11.293	EPSD	TCGA;ICGC	7.780	Down-regulation
AGC_Akt_AKT1_ST	Q9UNN5	FAF1	P31749	AKT1	S582	P581S	581	Missense	proximal	-1	no	16.824	16.853	PhosphoSitePlus	TCGA;ICGC;COSMIC	7.780	Up-regulation
AGC_Akt_AKT1_ST	Q9UNN5	FAF1	P31749	AKT1	S582	R577W	577	Missense	distal	-5	no	16.824	11.304	PhosphoSitePlus	TCGA;ICGC	7.780	Down-regulation
AGC_Akt_AKT1_ST	Q9UNN5	FAF1	P31749	AKT1	S582	F585L	585	Missense	distal	3	no	16.824	16.825	PhosphoSitePlus	TCGA;ICGC;COSMIC	7.780	Up-regulation
AGC_Akt_AKT1_ST	Q9UNN5	FAF1	P31749	AKT1	S582	S582N	582	Missense	central	0	yes	16.824	0.000	PhosphoSitePlus	TCGA;ICGC	7.780	Loss
AGC_Akt_AKT1_ST	Q09472	EP300	P31749	AKT1	S19	K14Q	14	Missense	distal	-5	no	8.729	6.899	EPSD	TCGA;ICGC;COSMIC	7.780	Loss
AGC_Akt_AKT1_ST	Q09472	EP300	P31749	AKT1	S19	K17E	17	Missense	proximal	-2	no	8.729	8.070	EPSD	TCGA;ICGC;COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	Q09472	EP300	P31749	AKT1	S19	A25P	25	Missense	distal	6	no	8.729	8.718	EPSD	TCGA;ICGC;COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	Q09472	EP300	P31749	AKT1	S19	P21A	21	Missense	proximal	2	no	8.729	8.689	EPSD	TCGA;ICGC;COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	Q09472	EP300	P31749	AKT1	S20	K14Q	14	Missense	distal	-6	no	11.821	11.751	EPSD	TCGA;ICGC;COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	Q09472	EP300	P31749	AKT1	S20	K17E	17	Missense	distal	-3	no	11.821	9.770	EPSD	TCGA;ICGC;COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	Q09472	EP300	P31749	AKT1	S20	A25P	25	Missense	distal	5	no	11.821	11.819	EPSD	TCGA;ICGC;COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	Q09472	EP300	P31749	AKT1	S20	P21A	21	Missense	proximal	1	no	11.821	11.903	EPSD	TCGA;ICGC;COSMIC	7.780	Up-regulation
AGC_Akt_AKT1_ST	Q09472	EP300	P31749	AKT1	S89	N94S	94	Missense	distal	5	no	11.079	11.113	EPSD	TCGA;ICGC;COSMIC	7.780	Up-regulation
AGC_Akt_AKT1_ST	Q09472	EP300	P31749	AKT1	S89	L84S	84	Missense	distal	-5	no	11.079	10.735	EPSD	TCGA;COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	Q09472	EP300	P31749	AKT1	S89	R86Q	86	Missense	distal	-3	no	11.079	3.868	EPSD	TCGA;ICGC	7.780	Loss
AGC_Akt_AKT1_ST	Q09472	EP300	P31749	AKT1	S831	H828Y	828	Missense	distal	-3	no	8.571	5.681	EPSD	TCGA;ICGC;COSMIC	7.780	Loss
AGC_Akt_AKT1_ST	Q09472	EP300	P31749	AKT1	S831	S833L	833	Missense	proximal	2	no	8.571	8.026	EPSD	TCGA;ICGC;COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	Q09472	EP300	P31749	AKT1	S1072	P1074S	1074	Missense	proximal	2	no	9.721	10.057	EPSD	TCGA;ICGC;COSMIC	7.780	Up-regulation
AGC_Akt_AKT1_ST	Q09472	EP300	P31749	AKT1	S1072	R1076C	1076	Missense	distal	4	no	9.721	10.055	EPSD	TCGA;ICGC;COSMIC	7.780	Up-regulation
AGC_Akt_AKT1_ST	Q09472	EP300	P31749	AKT1	T1190	D1188H	1188	Missense	proximal	-2	no	8.801	9.144	EPSD	TCGA;ICGC;COSMIC	7.780	Up-regulation
AGC_Akt_AKT1_ST	Q09472	EP300	P31749	AKT1	T1190	I1185V	1185	Missense	distal	-5	no	8.801	9.053	EPSD	TCGA;COSMIC	7.780	Up-regulation
AGC_Akt_AKT1_ST	Q09472	EP300	P31749	AKT1	T1190	A1189V	1189	Missense	proximal	-1	no	8.801	8.786	EPSD	TCGA;ICGC;COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	Q09472	EP300	P31749	AKT1	T1632	R1627G	1627	Missense	distal	-5	no	7.981	3.916	EPSD	TCGA;ICGC;COSMIC	7.780	Loss
AGC_Akt_AKT1_ST	Q09472	EP300	P31749	AKT1	T1632	R1627W	1627	Missense	distal	-5	no	7.981	2.461	EPSD	TCGA;ICGC;COSMIC;CCLE	7.780	Loss
AGC_Akt_AKT1_ST	Q09472	EP300	P31749	AKT1	T1632	A1629V	1629	Missense	distal	-3	no	7.981	7.418	EPSD	TCGA;ICGC;COSMIC	7.780	Loss
AGC_Akt_AKT1_ST	Q09472	EP300	P31749	AKT1	S1734	I1739M	1739	Missense	distal	5	no	12.320	12.360	EPSD	TCGA;ICGC;COSMIC	7.780	Up-regulation
AGC_Akt_AKT1_ST	Q09472	EP300	P31749	AKT1	S1734	R1737C	1737	Missense	distal	3	no	12.320	12.160	EPSD	TCGA;ICGC;COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	Q09472	EP300	P31749	AKT1	S1734	I1735T	1735	Missense	proximal	1	no	12.320	12.762	EPSD	TCGA;ICGC	7.780	Up-regulation
AGC_Akt_AKT1_ST	Q09472	EP300	P31749	AKT1	S1754	K1760R	1760	Missense	distal	6	no	10.638	10.627	EPSD	TCGA;ICGC;COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	Q09472	EP300	P31749	AKT1	S1754	C1753F	1753	Missense	proximal	-1	no	10.638	10.664	EPSD	TCGA;ICGC;COSMIC	7.780	Up-regulation
AGC_Akt_AKT1_ST	Q09472	EP300	P31749	AKT1	S1754	R1749Q	1749	Missense	distal	-5	no	10.638	6.411	EPSD	TCGA;ICGC	7.780	Loss
AGC_Akt_AKT1_ST	Q09472	EP300	P31749	AKT1	S1834	R1829C	1829	Missense	distal	-5	no	16.157	12.080	PhosphoSitePlus	TCGA;ICGC;COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	Q09472	EP300	P31749	AKT1	S1834	R1830S	1830	Missense	distal	-4	no	16.157	16.071	PhosphoSitePlus	TCGA;ICGC;COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	Q09472	EP300	P31749	AKT1	S1834	L1828F	1828	Missense	distal	-6	no	16.157	16.133	PhosphoSitePlus	TCGA;ICGC;COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	Q09472	EP300	P31749	AKT1	S2320	R2317Q	2317	Missense	distal	-3	no	10.616	3.405	EPSD	TCGA;ICGC;COSMIC	7.780	Loss
AGC_Akt_AKT1_ST	Q09472	EP300	P31749	AKT1	S2320	P2327H	2327	Missense	distal	7	no	10.616	10.611	EPSD	TCGA;ICGC	7.780	Down-regulation
AGC_Akt_AKT1_ST	Q09472	EP300	P31749	AKT1	S2320	R2317L	2317	Missense	distal	-3	no	10.616	3.623	EPSD	TCGA;ICGC;COSMIC	7.780	Loss
AGC_Akt_AKT1_ST	Q99623	PHB2	P31749	AKT1	S91	G95C	95	Missense	distal	4	no	16.515	16.687	PhosphoSitePlus;EPSD	TCGA;ICGC;COSMIC	7.780	Up-regulation
AGC_Akt_AKT1_ST	Q99623	PHB2	P31749	AKT1	S151	N149S	149	Missense	proximal	-2	no	7.276	7.961	EPSD	TCGA;ICGC;COSMIC	7.780	Gain
AGC_Akt_AKT1_ST	Q99623	PHB2	P31749	AKT1	T194	A195D	195	Missense	proximal	1	no	10.881	10.741	EPSD	TCGA;ICGC	7.780	Down-regulation
AGC_Akt_AKT1_ST	Q9UBP6	METTL1	P31749	AKT1	S27	N28D	28	Missense	proximal	1	no	16.706	16.581	PhosphoSitePlus	TCGA;ICGC;COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	Q9UBP6	METTL1	P31749	AKT1	S27	A25V	25	Missense	proximal	-2	no	16.706	15.968	PhosphoSitePlus	TCGA;ICGC;COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	Q9UBP6	METTL1	P31749	AKT1	S177	I176M	176	Missense	proximal	-1	no	12.435	12.456	EPSD	TCGA;ICGC;COSMIC	7.780	Up-regulation
AGC_Akt_AKT1_ST	P17302	GJA1	P31749	AKT1	S244	R239Q	239	Missense	distal	-5	no	11.197	6.969	EPSD	TCGA;ICGC;COSMIC	7.780	Loss
AGC_Akt_AKT1_ST	P17302	GJA1	P31749	AKT1	S244	G242E	242	Missense	proximal	-2	no	11.197	11.483	EPSD	TCGA;ICGC;COSMIC	7.780	Up-regulation
AGC_Akt_AKT1_ST	P17302	GJA1	P31749	AKT1	S244	R239W	239	Missense	distal	-5	no	11.197	5.677	EPSD	TCGA;ICGC;COSMIC	7.780	Loss
AGC_Akt_AKT1_ST	P17302	GJA1	P31749	AKT1	S244	D245N	245	Missense	proximal	1	no	11.197	11.321	EPSD	TCGA	7.780	Up-regulation
AGC_Akt_AKT1_ST	P17302	GJA1	P31749	AKT1	S296	R299H	299	Missense	distal	3	no	9.909	9.825	EPSD	TCGA;COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	P17302	GJA1	P31749	AKT1	S296	R293K	293	Missense	distal	-3	no	9.909	5.389	EPSD	TCGA;ICGC;COSMIC	7.780	Loss
AGC_Akt_AKT1_ST	P17302	GJA1	P31749	AKT1	S296	C298S	298	Missense	proximal	2	no	9.909	10.734	EPSD	TCGA;ICGC;COSMIC	7.780	Up-regulation
AGC_Akt_AKT1_ST	P17302	GJA1	P31749	AKT1	S296	S296F	296	Missense	central	0	yes	9.909	0.000	EPSD	TCGA;ICGC;COSMIC	7.780	Loss
AGC_Akt_AKT1_ST	P17302	GJA1	P31749	AKT1	S296	S296Y	296	Missense	central	0	yes	9.909	0.000	EPSD	TCGA;ICGC	7.780	Loss
AGC_Akt_AKT1_ST	P17302	GJA1	P31749	AKT1	S365	V359L	359	Missense	distal	-6	no	13.378	13.403	EPSD	TCGA;ICGC;COSMIC	7.780	Up-regulation
AGC_Akt_AKT1_ST	P17302	GJA1	P31749	AKT1	S365	S369N	369	Missense	distal	4	no	13.378	13.487	EPSD	TCGA;ICGC;COSMIC	7.780	Up-regulation
AGC_Akt_AKT1_ST	P17302	GJA1	P31749	AKT1	S368	S369N	369	Missense	proximal	1	no	7.958	7.870	EPSD	TCGA;ICGC;COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	P17302	GJA1	P31749	AKT1	S369	S369N	369	Missense	central	0	yes	14.385	0.000	EPSD	TCGA;ICGC;COSMIC	7.780	Loss
AGC_Akt_AKT1_ST	P17302	GJA1	P31749	AKT1	S372	S369N	369	Missense	distal	-3	no	8.283	8.583	EPSD	TCGA;ICGC;COSMIC	7.780	Up-regulation
AGC_Akt_AKT1_ST	P17302	GJA1	P31749	AKT1	S373	S369N	369	Missense	distal	-4	no	14.796	14.229	PhosphoSitePlus	TCGA;ICGC;COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	Q9H4X1	RGCC	P31749	AKT1	S64	R59H	59	Missense	distal	-5	no	11.300	8.205	EPSD	TCGA;ICGC;COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	Q9H4X1	RGCC	P31749	AKT1	S64	S65N	65	Missense	proximal	1	no	11.300	11.211	EPSD	TCGA;ICGC;COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	Q9H4X1	RGCC	P31749	AKT1	S65	R59H	59	Missense	distal	-6	no	12.435	12.317	EPSD	TCGA;ICGC;COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	Q9H4X1	RGCC	P31749	AKT1	S65	S65N	65	Missense	central	0	yes	12.435	0.000	EPSD	TCGA;ICGC;COSMIC	7.780	Loss
AGC_Akt_AKT1_ST	Q9H4X1	RGCC	P31749	AKT1	S67	S65N	65	Missense	proximal	-2	no	9.315	8.629	EPSD	TCGA;ICGC;COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	P06748	NPM1	P31749	AKT1	S48	D55N	55	Missense	distal	7	no	11.025	11.067	PhosphoSitePlus	TCGA;ICGC;COSMIC	7.780	Up-regulation
AGC_Akt_AKT1_ST	P06748	NPM1	P31749	AKT1	S48	A53S	53	Missense	distal	5	no	11.025	11.076	PhosphoSitePlus	TCGA;ICGC;COSMIC	7.780	Up-regulation
AGC_Akt_AKT1_ST	P06748	NPM1	P31749	AKT1	S48	V47F	47	Missense	proximal	-1	no	11.025	11.026	PhosphoSitePlus	TCGA;ICGC;COSMIC	7.780	Up-regulation
AGC_Akt_AKT1_ST	P06748	NPM1	P31749	AKT1	S48	S43Y	43	Missense	distal	-5	no	11.025	10.887	PhosphoSitePlus	TCGA;ICGC;COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	P06748	NPM1	P31749	AKT1	S106	S106L	106	Missense	central	0	yes	9.646	0.000	EPSD	TCGA;ICGC;COSMIC	7.780	Loss
AGC_Akt_AKT1_ST	Q92945	KHSRP	P31749	AKT1	S193	R190C	190	Missense	distal	-3	no	13.425	7.251	PhosphoSitePlus	TCGA;ICGC	7.780	Loss
AGC_Akt_AKT1_ST	Q92945	KHSRP	P31749	AKT1	S193	E199D	199	Missense	distal	6	no	13.425	13.334	PhosphoSitePlus	TCGA;ICGC;COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	Q92945	KHSRP	P31749	AKT1	T195	R190C	190	Missense	distal	-5	no	10.007	5.930	EPSD	TCGA;ICGC	7.780	Loss
AGC_Akt_AKT1_ST	Q92945	KHSRP	P31749	AKT1	T195	E199D	199	Missense	distal	4	no	10.007	10.153	EPSD	TCGA;ICGC;COSMIC	7.780	Up-regulation
AGC_Akt_AKT1_ST	Q92945	KHSRP	P31749	AKT1	S319	S319C	319	Missense	central	0	yes	7.921	0.000	EPSD	TCGA;ICGC;COSMIC	7.780	Loss
AGC_Akt_AKT1_ST	Q92945	KHSRP	P31749	AKT1	S319	R314Q	314	Missense	distal	-5	no	7.921	3.693	EPSD	TCGA;ICGC;COSMIC	7.780	Loss
AGC_Akt_AKT1_ST	Q92945	KHSRP	P31749	AKT1	S319	R320W	320	Missense	proximal	1	no	7.921	7.628	EPSD	TCGA;ICGC;COSMIC	7.780	Loss
AGC_Akt_AKT1_ST	O60331	PIP5K1C	P31749	AKT1	T135	P138H	138	Missense	distal	3	no	9.425	9.406	EPSD	TCGA;ICGC	7.780	Down-regulation
AGC_Akt_AKT1_ST	O60331	PIP5K1C	P31749	AKT1	S448	P454A	454	Missense	distal	6	no	12.315	12.326	EPSD	TCGA;ICGC;COSMIC	7.780	Up-regulation
AGC_Akt_AKT1_ST	O60331	PIP5K1C	P31749	AKT1	S448	R445W	445	Missense	distal	-3	no	12.315	3.375	EPSD	TCGA;ICGC;COSMIC	7.780	Loss
AGC_Akt_AKT1_ST	O60331	PIP5K1C	P31749	AKT1	S449	P454A	454	Missense	distal	5	no	9.630	9.632	EPSD	TCGA;ICGC;COSMIC	7.780	Up-regulation
AGC_Akt_AKT1_ST	O60331	PIP5K1C	P31749	AKT1	S449	R445W	445	Missense	distal	-4	no	9.630	8.081	EPSD	TCGA;ICGC;COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	O60331	PIP5K1C	P31749	AKT1	S541	S541L	541	Missense	central	0	yes	11.411	0.000	EPSD	TCGA;ICGC;COSMIC	7.780	Loss
AGC_Akt_AKT1_ST	O60331	PIP5K1C	P31749	AKT1	S541	S534F	534	Missense	distal	-7	no	11.411	11.133	EPSD	TCGA;ICGC;COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	O60331	PIP5K1C	P31749	AKT1	S541	R548W	548	Missense	distal	7	no	11.411	11.312	EPSD	TCGA;ICGC;COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	O60331	PIP5K1C	P31749	AKT1	S541	R548Q	548	Missense	distal	7	no	11.411	11.355	EPSD	TCGA;ICGC	7.780	Down-regulation
AGC_Akt_AKT1_ST	O60331	PIP5K1C	P31749	AKT1	S541	P540S	540	Missense	proximal	-1	no	11.411	11.440	EPSD	TCGA;ICGC;COSMIC	7.780	Up-regulation
AGC_Akt_AKT1_ST	O60331	PIP5K1C	P31749	AKT1	S541	R538Q	538	Missense	distal	-3	no	11.411	4.199	EPSD	TCGA;ICGC;COSMIC	7.780	Loss
AGC_Akt_AKT1_ST	O60331	PIP5K1C	P31749	AKT1	S541	R538W	538	Missense	distal	-3	no	11.411	2.470	EPSD	TCGA;ICGC	7.780	Loss
AGC_Akt_AKT1_ST	O60331	PIP5K1C	P31749	AKT1	T543	S541L	541	Missense	proximal	-2	no	10.500	9.643	EPSD	TCGA;ICGC;COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	O60331	PIP5K1C	P31749	AKT1	T543	R548W	548	Missense	distal	5	no	10.500	10.405	EPSD	TCGA;ICGC;COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	O60331	PIP5K1C	P31749	AKT1	T543	R548Q	548	Missense	distal	5	no	10.500	10.449	EPSD	TCGA;ICGC	7.780	Down-regulation
AGC_Akt_AKT1_ST	O60331	PIP5K1C	P31749	AKT1	T543	P540S	540	Missense	distal	-3	no	10.500	9.363	EPSD	TCGA;ICGC;COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	O60331	PIP5K1C	P31749	AKT1	T543	R538Q	538	Missense	distal	-5	no	10.500	6.273	EPSD	TCGA;ICGC;COSMIC	7.780	Loss
AGC_Akt_AKT1_ST	O60331	PIP5K1C	P31749	AKT1	T543	R538W	538	Missense	distal	-5	no	10.500	4.980	EPSD	TCGA;ICGC	7.780	Loss
AGC_Akt_AKT1_ST	O60331	PIP5K1C	P31749	AKT1	T553	R551Q	551	Missense	proximal	-2	no	14.941	14.429	EPSD	TCGA;ICGC;COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	O60331	PIP5K1C	P31749	AKT1	T553	R548W	548	Missense	distal	-5	no	14.941	9.422	EPSD	TCGA;ICGC;COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	O60331	PIP5K1C	P31749	AKT1	T553	R548Q	548	Missense	distal	-5	no	14.941	10.714	EPSD	TCGA;ICGC	7.780	Down-regulation
AGC_Akt_AKT1_ST	O60331	PIP5K1C	P31749	AKT1	T553	R551W	551	Missense	proximal	-2	no	14.941	13.687	EPSD	TCGA;ICGC;COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	O60331	PIP5K1C	P31749	AKT1	S555	R551Q	551	Missense	distal	-4	no	16.291	15.670	PhosphoSitePlus	TCGA;ICGC;COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	O60331	PIP5K1C	P31749	AKT1	S555	R548W	548	Missense	distal	-7	no	16.291	15.868	PhosphoSitePlus	TCGA;ICGC;COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	O60331	PIP5K1C	P31749	AKT1	S555	R548Q	548	Missense	distal	-7	no	16.291	16.097	PhosphoSitePlus	TCGA;ICGC	7.780	Down-regulation
AGC_Akt_AKT1_ST	O60331	PIP5K1C	P31749	AKT1	S555	R561S	561	Missense	distal	6	no	16.291	16.293	PhosphoSitePlus	TCGA;ICGC;COSMIC	7.780	Up-regulation
AGC_Akt_AKT1_ST	O60331	PIP5K1C	P31749	AKT1	S555	R561T	561	Missense	distal	6	no	16.291	16.313	PhosphoSitePlus	TCGA;ICGC;COSMIC	7.780	Up-regulation
AGC_Akt_AKT1_ST	O60331	PIP5K1C	P31749	AKT1	S555	R551W	551	Missense	distal	-4	no	16.291	14.742	PhosphoSitePlus	TCGA;ICGC;COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	O60331	PIP5K1C	P31749	AKT1	S556	R551Q	551	Missense	distal	-5	no	8.805	4.577	EPSD	TCGA;ICGC;COSMIC	7.780	Loss
AGC_Akt_AKT1_ST	O60331	PIP5K1C	P31749	AKT1	S556	R561S	561	Missense	distal	5	no	8.805	8.797	EPSD	TCGA;ICGC;COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	O60331	PIP5K1C	P31749	AKT1	S556	R561T	561	Missense	distal	5	no	8.805	8.798	EPSD	TCGA;ICGC;COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	O60331	PIP5K1C	P31749	AKT1	S556	R551W	551	Missense	distal	-5	no	8.805	3.285	EPSD	TCGA;ICGC;COSMIC	7.780	Loss
AGC_Akt_AKT1_ST	O60331	PIP5K1C	P31749	AKT1	S650	D643N	643	Missense	distal	-7	no	7.851	8.108	EPSD	TCGA;ICGC	7.780	Up-regulation
AGC_Akt_AKT1_ST	O60331	PIP5K1C	P31749	AKT1	S650	E644D	644	Missense	distal	-6	no	7.851	7.779	EPSD	TCGA;ICGC;COSMIC	7.780	Loss
AGC_Akt_AKT1_ST	O60331	PIP5K1C	P31749	AKT1	S650	Y654C	654	Missense	distal	4	no	7.851	8.060	EPSD	TCGA;ICGC;COSMIC	7.780	Up-regulation
AGC_Akt_AKT1_ST	O60331	PIP5K1C	P31749	AKT1	S650	H653Y	653	Missense	distal	3	no	7.851	7.883	EPSD	TCGA;ICGC;COSMIC	7.780	Up-regulation
AGC_Akt_AKT1_ST	O60331	PIP5K1C	P31749	AKT1	S650	Y649H	649	Missense	proximal	-1	no	7.851	7.843	EPSD	TCGA;ICGC;COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	O60331	PIP5K1C	P31749	AKT1	S650	A656V	656	Missense	distal	6	no	7.851	7.819	EPSD	TCGA;ICGC;COSMIC;CCLE	7.780	Down-regulation
AGC_Akt_AKT1_ST	O60331	PIP5K1C	P31749	AKT1	S650	S646C	646	Missense	distal	-4	no	7.851	6.258	EPSD	TCGA;ICGC;COSMIC	7.780	Loss
AGC_Akt_AKT1_ST	Q12906	ILF3	P31749	AKT1	S20	K17R	17	Missense	distal	-3	no	6.349	10.869	EPSD	TCGA;ICGC	7.780	Gain
AGC_Akt_AKT1_ST	Q12906	ILF3	P31749	AKT1	S384	P383L	383	Missense	proximal	-1	no	8.205	8.206	EPSD	TCGA;ICGC;COSMIC	7.780	Up-regulation
AGC_Akt_AKT1_ST	Q12906	ILF3	P31749	AKT1	S477	E484K	484	Missense	distal	7	no	11.456	11.490	EPSD	TCGA;ICGC;COSMIC	7.780	Up-regulation
AGC_Akt_AKT1_ST	Q12906	ILF3	P31749	AKT1	S477	E480G	480	Missense	distal	3	no	11.456	11.406	EPSD	TCGA;ICGC;COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	Q12906	ILF3	P31749	AKT1	S477	D475G	475	Missense	proximal	-2	no	11.456	12.154	EPSD	TCGA;ICGC	7.780	Up-regulation
AGC_Akt_AKT1_ST	Q12906	ILF3	P31749	AKT1	S647	G650V	650	Missense	distal	3	no	16.183	16.184	PhosphoSitePlus	TCGA;COSMIC	7.780	Up-regulation
AGC_Akt_AKT1_ST	Q12906	ILF3	P31749	AKT1	S845	G842R	842	Missense	distal	-3	no	3.308	10.064	EPSD	TCGA;COSMIC	7.780	Gain
AGC_Akt_AKT1_ST	Q8IYJ3	SYTL1	P31749	AKT1	S111	M106T	106	Missense	distal	-5	no	13.062	13.855	EPSD	TCGA;ICGC;COSMIC	7.780	Up-regulation
AGC_Akt_AKT1_ST	Q8IYJ3	SYTL1	P31749	AKT1	S111	A104V	104	Missense	distal	-7	no	13.062	12.934	EPSD	TCGA;ICGC	7.780	Down-regulation
AGC_Akt_AKT1_ST	Q8IYJ3	SYTL1	P31749	AKT1	S111	S111I	111	Missense	central	0	yes	13.062	0.000	EPSD	TCGA;ICGC;COSMIC	7.780	Loss
AGC_Akt_AKT1_ST	Q8IYJ3	SYTL1	P31749	AKT1	T112	M106T	106	Missense	distal	-6	no	11.863	11.956	EPSD	TCGA;ICGC;COSMIC	7.780	Up-regulation
AGC_Akt_AKT1_ST	Q8IYJ3	SYTL1	P31749	AKT1	T112	S111I	111	Missense	proximal	-1	no	11.863	11.813	EPSD	TCGA;ICGC;COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	Q8IYJ3	SYTL1	P31749	AKT1	S237	S241L	241	Missense	distal	4	no	10.420	10.609	EPSD	TCGA;COSMIC	7.780	Up-regulation
AGC_Akt_AKT1_ST	Q8IYJ3	SYTL1	P31749	AKT1	S237	R234H	234	Missense	distal	-3	no	10.420	5.721	EPSD	TCGA;COSMIC	7.780	Loss
AGC_Akt_AKT1_ST	Q8IYJ3	SYTL1	P31749	AKT1	S239	S241L	241	Missense	proximal	2	no	10.114	9.568	EPSD	TCGA;COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	Q8IYJ3	SYTL1	P31749	AKT1	S239	R234H	234	Missense	distal	-5	no	10.114	7.019	EPSD	TCGA;COSMIC	7.780	Loss
AGC_Akt_AKT1_ST	Q8IYJ3	SYTL1	P31749	AKT1	S468	R467H	467	Missense	proximal	-1	no	9.752	9.707	EPSD	TCGA	7.780	Down-regulation
AGC_Akt_AKT1_ST	Q8IYJ3	SYTL1	P31749	AKT1	S470	R467H	467	Missense	distal	-3	no	12.416	7.717	EPSD	TCGA	7.780	Loss
AGC_Akt_AKT1_ST	Q8WYL5	SSH1	P31749	AKT1	S237	S237F	237	Missense	central	0	yes	10.340	0.000	EPSD	TCGA;ICGC;COSMIC	7.780	Loss
AGC_Akt_AKT1_ST	Q8WYL5	SSH1	P31749	AKT1	S237	T233M	233	Missense	distal	-4	no	10.340	9.374	EPSD	TCGA;ICGC;COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	Q8WYL5	SSH1	P31749	AKT1	S237	R234Q	234	Missense	distal	-3	no	10.340	3.128	EPSD	TCGA;ICGC;COSMIC	7.780	Loss
AGC_Akt_AKT1_ST	Q8WYL5	SSH1	P31749	AKT1	S402	R399H	399	Missense	distal	-3	no	11.598	6.899	EPSD	TCGA;ICGC;COSMIC	7.780	Loss
AGC_Akt_AKT1_ST	Q8WYL5	SSH1	P31749	AKT1	S402	V397L	397	Missense	distal	-5	no	11.598	11.786	EPSD	TCGA;ICGC;COSMIC	7.780	Up-regulation
AGC_Akt_AKT1_ST	Q8WYL5	SSH1	P31749	AKT1	S402	S400L	400	Missense	proximal	-2	no	11.598	10.741	EPSD	TCGA;ICGC;COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	Q8WYL5	SSH1	P31749	AKT1	T430	I429V	429	Missense	proximal	-1	no	12.426	12.441	EPSD	TCGA	7.780	Up-regulation
AGC_Akt_AKT1_ST	Q8WYL5	SSH1	P31749	AKT1	T430	R427C	427	Missense	distal	-3	no	12.426	6.253	EPSD	TCGA;ICGC;COSMIC	7.780	Loss
AGC_Akt_AKT1_ST	Q8WYL5	SSH1	P31749	AKT1	S441	Y443C	443	Missense	proximal	2	no	11.875	11.422	EPSD	TCGA;ICGC;COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	Q8WYL5	SSH1	P31749	AKT1	T462	P469L	469	Missense	distal	7	no	8.742	8.734	EPSD	TCGA;ICGC;COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	Q8WYL5	SSH1	P31749	AKT1	S464	P469L	469	Missense	distal	5	no	9.723	9.710	EPSD	TCGA;ICGC;COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	Q8WYL5	SSH1	P31749	AKT1	S515	F511L	511	Missense	distal	-4	no	11.612	11.656	EPSD	TCGA;ICGC	7.780	Up-regulation
AGC_Akt_AKT1_ST	Q8WYL5	SSH1	P31749	AKT1	S515	P508T	508	Missense	distal	-7	no	11.612	11.857	EPSD	TCGA;ICGC;COSMIC	7.780	Up-regulation
AGC_Akt_AKT1_ST	Q8WYL5	SSH1	P31749	AKT1	S581	P577S	577	Missense	distal	-4	no	7.081	7.817	EPSD	TCGA;ICGC;COSMIC	7.780	Gain
AGC_Akt_AKT1_ST	Q8WYL5	SSH1	P31749	AKT1	S583	G579S	579	Missense	distal	-4	no	14.261	14.991	EPSD	TCGA;ICGC;COSMIC	7.780	Up-regulation
AGC_Akt_AKT1_ST	Q8WYL5	SSH1	P31749	AKT1	S583	P577S	577	Missense	distal	-6	no	14.261	14.325	EPSD	TCGA;ICGC;COSMIC	7.780	Up-regulation
AGC_Akt_AKT1_ST	Q8WYL5	SSH1	P31749	AKT1	S696	R697T	697	Missense	proximal	1	no	8.131	8.179	EPSD	TCGA;ICGC;COSMIC	7.780	Up-regulation
AGC_Akt_AKT1_ST	Q8WYL5	SSH1	P31749	AKT1	S696	H693Y	693	Missense	distal	-3	no	8.131	5.240	EPSD	TCGA;ICGC;COSMIC	7.780	Loss
AGC_Akt_AKT1_ST	Q8WYL5	SSH1	P31749	AKT1	S696	P701L	701	Missense	distal	5	no	8.131	8.117	EPSD	TCGA;ICGC;COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	Q8WYL5	SSH1	P31749	AKT1	S777	K774R	774	Missense	distal	-3	no	6.517	11.037	EPSD	TCGA;ICGC;COSMIC	7.780	Gain
AGC_Akt_AKT1_ST	Q8WYL5	SSH1	P31749	AKT1	T826	R831W	831	Missense	distal	5	no	11.639	11.544	PhosphoSitePlus	TCGA;ICGC;COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	Q8WYL5	SSH1	P31749	AKT1	S834	P841S	841	Missense	distal	7	no	12.667	12.726	EPSD	TCGA;ICGC;COSMIC	7.780	Up-regulation
AGC_Akt_AKT1_ST	Q8WYL5	SSH1	P31749	AKT1	S834	R831W	831	Missense	distal	-3	no	12.667	3.727	EPSD	TCGA;ICGC;COSMIC	7.780	Loss
AGC_Akt_AKT1_ST	Q8WYL5	SSH1	P31749	AKT1	S937	R934Q	934	Missense	distal	-3	no	13.058	5.847	EPSD	TCGA;ICGC;COSMIC	7.780	Loss
AGC_Akt_AKT1_ST	Q8WYL5	SSH1	P31749	AKT1	S937	R934W	934	Missense	distal	-3	no	13.058	4.117	EPSD	TCGA;ICGC;COSMIC	7.780	Loss
AGC_Akt_AKT1_ST	Q8WYL5	SSH1	P31749	AKT1	S937	S940N	940	Missense	distal	3	no	13.058	13.002	EPSD	TCGA;ICGC;COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	Q8WYL5	SSH1	P31749	AKT1	T968	S970F	970	Missense	proximal	2	no	9.242	8.665	EPSD	TCGA;ICGC;COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	Q8WYL5	SSH1	P31749	AKT1	T968	R961W	961	Missense	distal	-7	no	9.242	8.819	EPSD	TCGA;ICGC;COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	O15111	CHUK	P31749	AKT1	T23	R18W	18	Missense	distal	-5	no	13.896	8.376	PhosphoSitePlus	TCGA;ICGC;COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	P35222	CTNNB1	P31749	AKT1	S37	G34R	34	Missense	distal	-3	no	4.644	11.400	EPSD	TCGA;COSMIC	7.780	Gain
AGC_Akt_AKT1_ST	P35222	CTNNB1	P31749	AKT1	S129	V136A	136	Missense	distal	7	no	8.080	8.084	EPSD	TCGA;COSMIC	7.780	Up-regulation
AGC_Akt_AKT1_ST	P35222	CTNNB1	P31749	AKT1	S129	Q123H	123	Missense	distal	-6	no	8.080	8.045	EPSD	TCGA;COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	P35222	CTNNB1	P31749	AKT1	S129	R124C	124	Missense	distal	-5	no	8.080	4.003	EPSD	TCGA	7.780	Loss
AGC_Akt_AKT1_ST	P35222	CTNNB1	P31749	AKT1	T332	E334A	334	Missense	proximal	2	no	11.856	11.669	EPSD	TCGA;COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	P35222	CTNNB1	P31749	AKT1	T332	K335T	335	Missense	distal	3	no	11.856	11.852	EPSD	TCGA;COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	P35222	CTNNB1	P31749	AKT1	T332	K335I	335	Missense	distal	3	no	11.856	11.722	EPSD	TCGA;COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	P35222	CTNNB1	P31749	AKT1	T332	Y333F	333	Missense	proximal	1	no	11.856	11.881	EPSD	TCGA;COSMIC	7.780	Up-regulation
AGC_Akt_AKT1_ST	P35222	CTNNB1	P31749	AKT1	T332	M328I	328	Missense	distal	-4	no	11.856	11.383	EPSD	TCGA;COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	P35222	CTNNB1	P31749	AKT1	T332	T339N	339	Missense	distal	7	no	11.856	11.810	EPSD	TCGA;COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	P35222	CTNNB1	P31749	AKT1	T332	E334K	334	Missense	proximal	2	no	11.856	12.061	EPSD	TCGA;COSMIC;GDSC;CCLE	7.780	Up-regulation
AGC_Akt_AKT1_ST	P35222	CTNNB1	P31749	AKT1	T332	L336P	336	Missense	distal	4	no	11.856	11.823	EPSD	TCGA;COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	P35222	CTNNB1	P31749	AKT1	T472	R469H	469	Missense	distal	-3	no	10.054	5.355	EPSD	TCGA;COSMIC	7.780	Loss
AGC_Akt_AKT1_ST	P35222	CTNNB1	P31749	AKT1	T472	R474Q	474	Missense	proximal	2	no	10.054	9.936	EPSD	TCGA;GDSC;CCLE	7.780	Down-regulation
AGC_Akt_AKT1_ST	P35222	CTNNB1	P31749	AKT1	T547	R542H	542	Missense	distal	-5	no	9.356	6.261	EPSD	TCGA;COSMIC	7.780	Loss
AGC_Akt_AKT1_ST	P35222	CTNNB1	P31749	AKT1	T547	M553V	553	Missense	distal	6	no	9.356	9.341	EPSD	TCGA;COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	P35222	CTNNB1	P31749	AKT1	T547	V541A	541	Missense	distal	-6	no	9.356	9.377	EPSD	TCGA;COSMIC	7.780	Up-regulation
AGC_Akt_AKT1_ST	P35222	CTNNB1	P31749	AKT1	S552	M553V	553	Missense	proximal	1	no	12.531	12.592	PhosphoSitePlus	TCGA;COSMIC	7.780	Up-regulation
AGC_Akt_AKT1_ST	P35222	CTNNB1	P31749	AKT1	S675	S681F	681	Missense	distal	6	no	7.903	7.783	EPSD	TCGA	7.780	Down-regulation
AGC_Akt_AKT1_ST	P35222	CTNNB1	P31749	AKT1	S715	R717H	717	Missense	proximal	2	no	9.638	9.277	EPSD	TCGA;COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	P35222	CTNNB1	P31749	AKT1	S715	P714R	714	Missense	proximal	-1	no	9.638	9.677	EPSD	TCGA;COSMIC	7.780	Up-regulation
AGC_Akt_AKT1_ST	P54274	TERF1	P31749	AKT1	T24	Q27H	27	Missense	distal	3	no	7.866	7.838	EPSD	TCGA;ICGC;COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	P54274	TERF1	P31749	AKT1	T24	A21V	21	Missense	distal	-3	no	7.866	7.304	EPSD	TCGA;ICGC;COSMIC	7.780	Loss
AGC_Akt_AKT1_ST	P54274	TERF1	P31749	AKT1	T24	T31R	31	Missense	distal	7	no	7.866	7.863	EPSD	TCGA;ICGC;COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	P54274	TERF1	P31749	AKT1	T24	R19G	19	Missense	distal	-5	no	7.866	3.801	EPSD	TCGA;ICGC;COSMIC	7.780	Loss
AGC_Akt_AKT1_ST	P54274	TERF1	P31749	AKT1	T24	A29V	29	Missense	distal	5	no	7.866	7.857	EPSD	TCGA;ICGC;COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	P54274	TERF1	P31749	AKT1	T271	R270K	270	Missense	proximal	-1	no	10.789	10.785	EPSD	TCGA;ICGC;COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	P54274	TERF1	P31749	AKT1	T271	R270S	270	Missense	proximal	-1	no	10.789	10.779	EPSD	TCGA;ICGC;COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	P54274	TERF1	P31749	AKT1	T271	D276H	276	Missense	distal	5	no	10.789	10.797	EPSD	TCGA;ICGC;COSMIC	7.780	Up-regulation
AGC_Akt_AKT1_ST	P54274	TERF1	P31749	AKT1	T273	R270K	270	Missense	distal	-3	no	15.133	10.613	PhosphoSitePlus	TCGA;ICGC;COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	P54274	TERF1	P31749	AKT1	T273	R270S	270	Missense	distal	-3	no	15.133	7.357	PhosphoSitePlus	TCGA;ICGC;COSMIC	7.780	Loss
AGC_Akt_AKT1_ST	P54274	TERF1	P31749	AKT1	T273	S279C	279	Missense	distal	6	no	15.133	14.930	PhosphoSitePlus	TCGA;ICGC;COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	P54274	TERF1	P31749	AKT1	T273	D276H	276	Missense	distal	3	no	15.133	15.145	PhosphoSitePlus	TCGA;ICGC;COSMIC	7.780	Up-regulation
AGC_Akt_AKT1_ST	P54274	TERF1	P31749	AKT1	T358	I362M	362	Missense	distal	4	no	12.453	12.355	EPSD	TCGA;COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	P54274	TERF1	P31749	AKT1	S434	S434F	434	Missense	central	0	yes	9.370	0.000	EPSD	TCGA;COSMIC	7.780	Loss
AGC_Akt_AKT1_ST	Q86VP3	PACS2	P31749	AKT1	T125	T131M	131	Missense	distal	6	no	10.903	10.784	EPSD	TCGA;COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	Q86VP3	PACS2	P31749	AKT1	T125	R118T	118	Missense	distal	-7	no	10.903	10.898	EPSD	TCGA;COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	Q86VP3	PACS2	P31749	AKT1	T125	Y121C	121	Missense	distal	-4	no	10.903	10.170	EPSD	TCGA;COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	Q86VP3	PACS2	P31749	AKT1	T125	T125A	125	Missense	central	0	yes	10.903	0.000	EPSD	TCGA;COSMIC	7.780	Loss
AGC_Akt_AKT1_ST	Q86VP3	PACS2	P31749	AKT1	T125	R124I	124	Missense	proximal	-1	no	10.903	10.844	EPSD	TCGA	7.780	Down-regulation
AGC_Akt_AKT1_ST	Q86VP3	PACS2	P31749	AKT1	T242	S238L	238	Missense	distal	-4	no	8.663	7.539	EPSD	TCGA;COSMIC	7.780	Loss
AGC_Akt_AKT1_ST	Q86VP3	PACS2	P31749	AKT1	T242	R236W	236	Missense	distal	-6	no	8.663	8.515	EPSD	TCGA;COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	Q86VP3	PACS2	P31749	AKT1	T242	R237I	237	Missense	distal	-5	no	8.663	4.095	EPSD	TCGA	7.780	Loss
AGC_Akt_AKT1_ST	Q86VP3	PACS2	P31749	AKT1	T242	T242M	242	Missense	central	0	yes	8.663	0.000	EPSD	TCGA;COSMIC	7.780	Loss
AGC_Akt_AKT1_ST	Q86VP3	PACS2	P31749	AKT1	T242	T246I	246	Missense	distal	4	no	8.663	8.929	EPSD	TCGA;COSMIC	7.780	Up-regulation
AGC_Akt_AKT1_ST	Q86VP3	PACS2	P31749	AKT1	S244	S238L	238	Missense	distal	-6	no	12.671	12.620	EPSD	TCGA;COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	Q86VP3	PACS2	P31749	AKT1	S244	N250Y	250	Missense	distal	6	no	12.671	12.650	EPSD	TCGA;COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	Q86VP3	PACS2	P31749	AKT1	S244	R237I	237	Missense	distal	-7	no	12.671	12.243	EPSD	TCGA	7.780	Down-regulation
AGC_Akt_AKT1_ST	Q86VP3	PACS2	P31749	AKT1	S244	T242M	242	Missense	proximal	-2	no	12.671	11.897	EPSD	TCGA;COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	Q86VP3	PACS2	P31749	AKT1	S244	T246I	246	Missense	proximal	2	no	12.671	12.089	EPSD	TCGA;COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	Q86VP3	PACS2	P31749	AKT1	T246	N250Y	250	Missense	distal	4	no	8.830	8.856	EPSD	TCGA;COSMIC	7.780	Up-regulation
AGC_Akt_AKT1_ST	Q86VP3	PACS2	P31749	AKT1	T246	T242M	242	Missense	distal	-4	no	8.830	7.864	EPSD	TCGA;COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	Q86VP3	PACS2	P31749	AKT1	T246	T246I	246	Missense	central	0	yes	8.830	0.000	EPSD	TCGA;COSMIC	7.780	Loss
AGC_Akt_AKT1_ST	Q86VP3	PACS2	P31749	AKT1	S359	E355K	355	Missense	distal	-4	no	7.478	8.061	EPSD	TCGA;COSMIC	7.780	Gain
AGC_Akt_AKT1_ST	Q86VP3	PACS2	P31749	AKT1	S416	P420H	420	Missense	distal	4	no	7.792	7.831	EPSD	TCGA;COSMIC	7.780	Up-regulation
AGC_Akt_AKT1_ST	Q86VP3	PACS2	P31749	AKT1	S416	E415G	415	Missense	proximal	-1	no	7.792	7.777	EPSD	TCGA;COSMIC	7.780	Loss
AGC_Akt_AKT1_ST	Q86VP3	PACS2	P31749	AKT1	S416	S416F	416	Missense	central	0	yes	7.792	0.000	EPSD	TCGA;COSMIC	7.780	Loss
AGC_Akt_AKT1_ST	Q86VP3	PACS2	P31749	AKT1	S435	S437F	437	Missense	proximal	2	no	12.145	11.567	EPSD	TCGA;COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	Q86VP3	PACS2	P31749	AKT1	T436	S437F	437	Missense	proximal	1	no	8.417	8.435	EPSD	TCGA;COSMIC	7.780	Up-regulation
AGC_Akt_AKT1_ST	Q86VP3	PACS2	P31749	AKT1	T436	A443V	443	Missense	distal	7	no	8.417	8.413	EPSD	TCGA	7.780	Down-regulation
AGC_Akt_AKT1_ST	Q86VP3	PACS2	P31749	AKT1	S437	S437F	437	Missense	central	0	yes	15.176	0.000	PhosphoSitePlus	TCGA;COSMIC	7.780	Loss
AGC_Akt_AKT1_ST	Q86VP3	PACS2	P31749	AKT1	S437	A443V	443	Missense	distal	6	no	15.176	15.144	PhosphoSitePlus	TCGA	7.780	Down-regulation
AGC_Akt_AKT1_ST	Q86VP3	PACS2	P31749	AKT1	S453	E449G	449	Missense	distal	-4	no	10.559	10.342	EPSD	TCGA	7.780	Down-regulation
AGC_Akt_AKT1_ST	Q99490	AGAP2	P31749	AKT1	S523	A521T	521	Missense	proximal	-2	no	8.050	8.435	EPSD	TCGA	7.780	Up-regulation
AGC_Akt_AKT1_ST	Q99490	AGAP2	P31749	AKT1	S523	A530T	530	Missense	distal	7	no	8.050	8.111	EPSD	TCGA;COSMIC	7.780	Up-regulation
AGC_Akt_AKT1_ST	Q99490	AGAP2	P31749	AKT1	S523	G528E	528	Missense	distal	5	no	8.050	8.080	EPSD	TCGA;COSMIC	7.780	Up-regulation
AGC_Akt_AKT1_ST	Q99490	AGAP2	P31749	AKT1	T605	G602R	602	Missense	distal	-3	no	2.827	9.583	EPSD	TCGA;COSMIC	7.780	Gain
AGC_Akt_AKT1_ST	Q99490	AGAP2	P31749	AKT1	S648	R645L	645	Missense	distal	-3	no	13.167	6.173	EPSD	TCGA;ICGC;COSMIC	7.780	Loss
AGC_Akt_AKT1_ST	Q99490	AGAP2	P31749	AKT1	S648	R653C	653	Missense	distal	5	no	13.167	13.040	EPSD	TCGA;COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	Q99490	AGAP2	P31749	AKT1	S648	A642E	642	Missense	distal	-6	no	13.167	13.175	EPSD	TCGA;COSMIC	7.780	Up-regulation
AGC_Akt_AKT1_ST	Q99490	AGAP2	P31749	AKT1	S648	R645C	645	Missense	distal	-3	no	13.167	6.993	EPSD	TCGA;ICGC;COSMIC	7.780	Loss
AGC_Akt_AKT1_ST	Q99490	AGAP2	P31749	AKT1	S656	R653C	653	Missense	distal	-3	no	11.284	5.111	EPSD	TCGA;COSMIC	7.780	Loss
AGC_Akt_AKT1_ST	Q99490	AGAP2	P31749	AKT1	S656	E659K	659	Missense	distal	3	no	11.284	11.328	EPSD	TCGA;COSMIC	7.780	Up-regulation
AGC_Akt_AKT1_ST	Q99490	AGAP2	P31749	AKT1	S656	K660E	660	Missense	distal	4	no	11.284	11.385	EPSD	TCGA	7.780	Up-regulation
AGC_Akt_AKT1_ST	Q99490	AGAP2	P31749	AKT1	S656	R661Q	661	Missense	distal	5	no	11.284	11.234	EPSD	TCGA;COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	Q99490	AGAP2	P31749	AKT1	S745	P740S	740	Missense	distal	-5	no	10.502	10.042	EPSD	TCGA;COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	Q99490	AGAP2	P31749	AKT1	S745	I744M	744	Missense	proximal	-1	no	10.502	10.523	EPSD	TCGA;COSMIC	7.780	Up-regulation
AGC_Akt_AKT1_ST	Q99490	AGAP2	P31749	AKT1	S745	G748D	748	Missense	distal	3	no	10.502	10.482	EPSD	TCGA;ICGC;COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	Q99490	AGAP2	P31749	AKT1	S745	A751T	751	Missense	distal	6	no	10.502	10.605	EPSD	TCGA;ICGC;COSMIC	7.780	Up-regulation
AGC_Akt_AKT1_ST	Q99490	AGAP2	P31749	AKT1	S745	A746T	746	Missense	proximal	1	no	10.502	10.769	EPSD	TCGA;ICGC;COSMIC	7.780	Up-regulation
AGC_Akt_AKT1_ST	Q99490	AGAP2	P31749	AKT1	S808	R805Q	805	Missense	distal	-3	no	11.078	3.867	EPSD	TCGA;COSMIC	7.780	Loss
AGC_Akt_AKT1_ST	Q99490	AGAP2	P31749	AKT1	T839	K836T	836	Missense	distal	-3	no	11.095	8.594	EPSD	TCGA;ICGC;COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	Q99490	AGAP2	P31749	AKT1	S927	R924H	924	Missense	distal	-3	no	13.704	9.006	EPSD	TCGA;ICGC;COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	Q99490	AGAP2	P31749	AKT1	S927	I934N	934	Missense	distal	7	no	13.704	13.766	EPSD	TCGA;ICGC;COSMIC	7.780	Up-regulation
AGC_Akt_AKT1_ST	Q99490	AGAP2	P31749	AKT1	S927	R924C	924	Missense	distal	-3	no	13.704	7.531	EPSD	TCGA;COSMIC	7.780	Loss
AGC_Akt_AKT1_ST	Q99490	AGAP2	P31749	AKT1	S929	R924H	924	Missense	distal	-5	no	10.635	7.540	EPSD	TCGA;ICGC;COSMIC	7.780	Loss
AGC_Akt_AKT1_ST	Q99490	AGAP2	P31749	AKT1	S929	I934N	934	Missense	distal	5	no	10.635	10.697	EPSD	TCGA;ICGC;COSMIC	7.780	Up-regulation
AGC_Akt_AKT1_ST	Q99490	AGAP2	P31749	AKT1	S929	R924C	924	Missense	distal	-5	no	10.635	6.558	EPSD	TCGA;COSMIC	7.780	Loss
AGC_Akt_AKT1_ST	Q99490	AGAP2	P31749	AKT1	S985	V983A	983	Missense	proximal	-2	no	11.831	12.569	EPSD	TCGA;ICGC	7.780	Up-regulation
AGC_Akt_AKT1_ST	Q8N6T7	SIRT6	P31749	AKT1	T294	R291C	291	Missense	distal	-3	no	10.514	4.341	EPSD	TCGA;ICGC;COSMIC	7.780	Loss
AGC_Akt_AKT1_ST	O14746	TERT	P31749	AKT1	S227	G220V	220	Missense	distal	-7	no	16.135	16.044	PhosphoSitePlus;EPSD	TCGA;ICGC;COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	O14746	TERT	P31749	AKT1	S227	G225R	225	Missense	proximal	-2	no	16.135	16.642	PhosphoSitePlus;EPSD	TCGA;ICGC;COSMIC;CCLE	7.780	Up-regulation
AGC_Akt_AKT1_ST	O14746	TERT	P31749	AKT1	T618	P614L	614	Missense	distal	-4	no	8.229	7.841	EPSD	TCGA;ICGC;COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	O14746	TERT	P31749	AKT1	T618	R622C	622	Missense	distal	4	no	8.229	8.563	EPSD	TCGA;ICGC;COSMIC	7.780	Up-regulation
AGC_Akt_AKT1_ST	O14746	TERT	P31749	AKT1	T618	T618M	618	Missense	central	0	yes	8.229	0.000	EPSD	TCGA;ICGC	7.780	Loss
AGC_Akt_AKT1_ST	O14746	TERT	P31749	AKT1	S824	V818L	818	Missense	distal	-6	no	14.874	14.899	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	7.780	Up-regulation
AGC_Akt_AKT1_ST	P21453	S1PR1	P31749	AKT1	T236	T230N	230	Missense	distal	-6	no	16.477	16.399	PhosphoSitePlus	TCGA;ICGC;COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	P21453	S1PR1	P31749	AKT1	T236	F237L	237	Missense	proximal	1	no	16.477	16.558	PhosphoSitePlus	TCGA;ICGC;COSMIC	7.780	Up-regulation
AGC_Akt_AKT1_ST	P21453	S1PR1	P31749	AKT1	T236	R234H	234	Missense	proximal	-2	no	16.477	15.616	PhosphoSitePlus	TCGA;ICGC	7.780	Down-regulation
AGC_Akt_AKT1_ST	P21453	S1PR1	P31749	AKT1	T236	K239N	239	Missense	distal	3	no	16.477	16.419	PhosphoSitePlus	TCGA;ICGC	7.780	Down-regulation
AGC_Akt_AKT1_ST	P21453	S1PR1	P31749	AKT1	T236	R231W	231	Missense	distal	-5	no	16.477	10.957	PhosphoSitePlus	TCGA;ICGC	7.780	Down-regulation
AGC_Akt_AKT1_ST	P21453	S1PR1	P31749	AKT1	S355	S351R	351	Missense	distal	-4	no	13.849	13.935	EPSD	TCGA;ICGC;COSMIC	7.780	Up-regulation
AGC_Akt_AKT1_ST	P21453	S1PR1	P31749	AKT1	S355	M348I	348	Missense	distal	-7	no	13.849	13.693	EPSD	TCGA;ICGC;COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	P21453	S1PR1	P31749	AKT1	S355	S355L	355	Missense	central	0	yes	13.849	0.000	EPSD	TCGA;ICGC;COSMIC	7.780	Loss
AGC_Akt_AKT1_ST	P21453	S1PR1	P31749	AKT1	S355	R352H	352	Missense	distal	-3	no	13.849	9.150	EPSD	TCGA;ICGC	7.780	Down-regulation
AGC_Akt_AKT1_ST	P46937	YAP1	P31749	AKT1	S61	S61W	61	Missense	central	0	yes	11.635	0.000	EPSD	TCGA;ICGC;COSMIC	7.780	Loss
AGC_Akt_AKT1_ST	P46937	YAP1	P31749	AKT1	T63	S61W	61	Missense	proximal	-2	no	8.987	7.544	EPSD	TCGA;ICGC;COSMIC	7.780	Loss
AGC_Akt_AKT1_ST	P46937	YAP1	P31749	AKT1	S94	F95C	95	Missense	proximal	1	no	8.520	8.119	EPSD	TCGA;ICGC	7.780	Down-regulation
AGC_Akt_AKT1_ST	P46937	YAP1	P31749	AKT1	S105	R106Q	106	Missense	proximal	1	no	8.034	7.739	EPSD	TCGA;ICGC;COSMIC;CCLE	7.780	Loss
AGC_Akt_AKT1_ST	P46937	YAP1	P31749	AKT1	S105	S109N	109	Missense	distal	4	no	8.034	8.143	EPSD	TCGA;ICGC;COSMIC	7.780	Up-regulation
AGC_Akt_AKT1_ST	P46937	YAP1	P31749	AKT1	S109	R106Q	106	Missense	distal	-3	no	13.488	6.277	EPSD	TCGA;ICGC;COSMIC;CCLE	7.780	Loss
AGC_Akt_AKT1_ST	P46937	YAP1	P31749	AKT1	S109	S109N	109	Missense	central	0	yes	13.488	0.000	EPSD	TCGA;ICGC;COSMIC	7.780	Loss
AGC_Akt_AKT1_ST	P46937	YAP1	P31749	AKT1	S127	Q121H	121	Missense	distal	-6	no	11.042	11.007	PhosphoSitePlus	TCGA;ICGC;COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	P46937	YAP1	P31749	AKT1	S127	P129S	129	Missense	proximal	2	no	11.042	11.378	PhosphoSitePlus	TCGA;ICGC;COSMIC	7.780	Up-regulation
AGC_Akt_AKT1_ST	P46937	YAP1	P31749	AKT1	S127	R124P	124	Missense	distal	-3	no	11.042	4.402	PhosphoSitePlus	TCGA;ICGC;COSMIC	7.780	Loss
AGC_Akt_AKT1_ST	P46937	YAP1	P31749	AKT1	S127	R124Q	124	Missense	distal	-3	no	11.042	3.830	PhosphoSitePlus	TCGA;ICGC;COSMIC	7.780	Loss
AGC_Akt_AKT1_ST	P46937	YAP1	P31749	AKT1	S164	Q158H	158	Missense	distal	-6	no	11.562	11.528	EPSD	TCGA;ICGC;COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	P46937	YAP1	P31749	AKT1	S164	I167M	167	Missense	distal	3	no	11.562	11.608	EPSD	TCGA;ICGC	7.780	Up-regulation
AGC_Akt_AKT1_ST	P46937	YAP1	P31749	AKT1	S257	R262M	262	Missense	distal	5	no	9.146	9.081	EPSD	TCGA;ICGC;COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	P46937	YAP1	P31749	AKT1	S257	S257F	257	Missense	central	0	yes	9.146	0.000	EPSD	TCGA;ICGC;COSMIC	7.780	Loss
AGC_Akt_AKT1_ST	P46937	YAP1	P31749	AKT1	T378	D383E	383	Missense	distal	5	no	9.656	9.699	EPSD	TCGA;ICGC;COSMIC	7.780	Up-regulation
AGC_Akt_AKT1_ST	P46937	YAP1	P31749	AKT1	S397	E396D	396	Missense	proximal	-1	no	12.580	12.546	EPSD	TCGA;ICGC;COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	P46937	YAP1	P31749	AKT1	S499	L501F	501	Missense	proximal	2	no	9.760	9.728	EPSD	TCGA;ICGC;COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	Q9H9Q4	NHEJ1	P31749	AKT1	T181	R178Q	178	Missense	distal	-3	no	13.742	6.531	PhosphoSitePlus	TCGA;ICGC;COSMIC	7.780	Loss
AGC_Akt_AKT1_ST	Q9NWV8	BABAM1	P31749	AKT1	T27	S20L	20	Missense	distal	-7	no	11.107	10.874	EPSD	TCGA;ICGC;COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	Q9NWV8	BABAM1	P31749	AKT1	T27	R26H	26	Missense	proximal	-1	no	11.107	11.063	EPSD	TCGA;ICGC	7.780	Down-regulation
AGC_Akt_AKT1_ST	Q9NWV8	BABAM1	P31749	AKT1	S29	R26H	26	Missense	distal	-3	no	15.557	10.858	PhosphoSitePlus	TCGA;ICGC	7.780	Down-regulation
AGC_Akt_AKT1_ST	Q9NWV8	BABAM1	P31749	AKT1	S116	G115A	115	Missense	proximal	-1	no	8.098	8.107	EPSD	TCGA;ICGC;COSMIC	7.780	Up-regulation
AGC_Akt_AKT1_ST	Q86TI0	TBC1D1	P31749	AKT1	S235	F236L	236	Missense	proximal	1	no	8.951	9.032	EPSD	TCGA;ICGC;COSMIC	7.780	Up-regulation
AGC_Akt_AKT1_ST	Q86TI0	TBC1D1	P31749	AKT1	S235	G240S	240	Missense	distal	5	no	8.951	9.014	EPSD	TCGA;ICGC;COSMIC	7.780	Up-regulation
AGC_Akt_AKT1_ST	Q86TI0	TBC1D1	P31749	AKT1	S235	M232V	232	Missense	distal	-3	no	8.951	9.592	EPSD	TCGA;ICGC;COSMIC	7.780	Up-regulation
AGC_Akt_AKT1_ST	Q86TI0	TBC1D1	P31749	AKT1	S235	R233H	233	Missense	proximal	-2	no	8.951	8.091	EPSD	TCGA;ICGC	7.780	Down-regulation
AGC_Akt_AKT1_ST	Q86TI0	TBC1D1	P31749	AKT1	S237	F236L	236	Missense	proximal	-1	no	9.224	9.230	EPSD	TCGA;ICGC;COSMIC	7.780	Up-regulation
AGC_Akt_AKT1_ST	Q86TI0	TBC1D1	P31749	AKT1	S237	G240S	240	Missense	distal	3	no	9.224	9.315	EPSD	TCGA;ICGC;COSMIC	7.780	Up-regulation
AGC_Akt_AKT1_ST	Q86TI0	TBC1D1	P31749	AKT1	S237	M232V	232	Missense	distal	-5	no	9.224	9.432	EPSD	TCGA;ICGC;COSMIC	7.780	Up-regulation
AGC_Akt_AKT1_ST	Q86TI0	TBC1D1	P31749	AKT1	S237	R233H	233	Missense	distal	-4	no	9.224	8.165	EPSD	TCGA;ICGC	7.780	Down-regulation
AGC_Akt_AKT1_ST	Q86TI0	TBC1D1	P31749	AKT1	T294	R289Q	289	Missense	distal	-5	no	8.234	4.006	EPSD	TCGA;ICGC;COSMIC;GDSC;CCLE	7.780	Loss
AGC_Akt_AKT1_ST	Q86TI0	TBC1D1	P31749	AKT1	T505	S503Y	503	Missense	proximal	-2	no	12.351	11.429	EPSD	TCGA	7.780	Down-regulation
AGC_Akt_AKT1_ST	Q86TI0	TBC1D1	P31749	AKT1	S507	R514Q	514	Missense	distal	7	no	9.996	9.940	EPSD	TCGA;ICGC;COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	Q86TI0	TBC1D1	P31749	AKT1	S507	S503Y	503	Missense	distal	-4	no	9.996	9.137	EPSD	TCGA	7.780	Down-regulation
AGC_Akt_AKT1_ST	Q86TI0	TBC1D1	P31749	AKT1	S527	S532N	532	Missense	distal	5	no	7.920	7.886	EPSD	TCGA;ICGC;COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	Q86TI0	TBC1D1	P31749	AKT1	S565	L562F	562	Missense	distal	-3	no	7.050	8.449	EPSD	TCGA;ICGC	7.780	Gain
AGC_Akt_AKT1_ST	Q86TI0	TBC1D1	P31749	AKT1	T596	E603K	603	Missense	distal	7	no	15.087	15.121	PhosphoSitePlus	TCGA;ICGC;COSMIC	7.780	Up-regulation
AGC_Akt_AKT1_ST	Q86TI0	TBC1D1	P31749	AKT1	T596	P601S	601	Missense	distal	5	no	15.087	15.140	PhosphoSitePlus	TCGA;ICGC;COSMIC	7.780	Up-regulation
AGC_Akt_AKT1_ST	Q86TI0	TBC1D1	P31749	AKT1	S598	E603K	603	Missense	distal	5	no	7.836	7.870	EPSD	TCGA;ICGC;COSMIC	7.780	Up-regulation
AGC_Akt_AKT1_ST	Q86TI0	TBC1D1	P31749	AKT1	S598	P601S	601	Missense	distal	3	no	7.836	7.917	EPSD	TCGA;ICGC;COSMIC	7.780	Up-regulation
AGC_Akt_AKT1_ST	Q86TI0	TBC1D1	P31749	AKT1	S627	M623I	623	Missense	distal	-4	no	11.603	11.131	EPSD	TCGA;ICGC;COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	Q86TI0	TBC1D1	P31749	AKT1	S627	L622R	622	Missense	distal	-5	no	11.603	15.729	EPSD	TCGA;ICGC;COSMIC	7.780	Up-regulation
AGC_Akt_AKT1_ST	Q86TI0	TBC1D1	P31749	AKT1	S627	H626Y	626	Missense	proximal	-1	no	11.603	11.611	EPSD	TCGA;ICGC;COSMIC	7.780	Up-regulation
AGC_Akt_AKT1_ST	Q86TI0	TBC1D1	P31749	AKT1	S627	L622P	622	Missense	distal	-5	no	11.603	11.719	EPSD	TCGA;ICGC;COSMIC	7.780	Up-regulation
AGC_Akt_AKT1_ST	Q86TI0	TBC1D1	P31749	AKT1	S629	M623I	623	Missense	distal	-6	no	11.727	11.669	EPSD	TCGA;ICGC;COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	Q86TI0	TBC1D1	P31749	AKT1	S629	L622R	622	Missense	distal	-7	no	11.727	12.017	EPSD	TCGA;ICGC;COSMIC	7.780	Up-regulation
AGC_Akt_AKT1_ST	Q86TI0	TBC1D1	P31749	AKT1	S629	H626Y	626	Missense	distal	-3	no	11.727	8.837	EPSD	TCGA;ICGC;COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	Q86TI0	TBC1D1	P31749	AKT1	S629	L622P	622	Missense	distal	-7	no	11.727	11.767	EPSD	TCGA;ICGC;COSMIC	7.780	Up-regulation
AGC_Akt_AKT1_ST	Q86TI0	TBC1D1	P31749	AKT1	S660	R657W	657	Missense	distal	-3	no	15.256	6.316	EPSD	TCGA;ICGC;COSMIC	7.780	Loss
AGC_Akt_AKT1_ST	Q86TI0	TBC1D1	P31749	AKT1	S660	S660F	660	Missense	central	0	yes	15.256	0.000	EPSD	TCGA;ICGC;CCLE	7.780	Loss
AGC_Akt_AKT1_ST	Q86TI0	TBC1D1	P31749	AKT1	T716	R718C	718	Missense	proximal	2	no	8.197	7.544	EPSD	TCGA;ICGC;COSMIC	7.780	Loss
AGC_Akt_AKT1_ST	Q86TI0	TBC1D1	P31749	AKT1	S717	R718C	718	Missense	proximal	1	no	8.913	8.384	EPSD	TCGA;ICGC;COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	Q86TI0	TBC1D1	P31749	AKT1	S1150	E1157V	1157	Missense	distal	7	no	11.421	11.400	EPSD	TCGA;ICGC;COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	Q86TI0	TBC1D1	P31749	AKT1	S1150	R1147W	1147	Missense	distal	-3	no	11.421	2.481	EPSD	TCGA;ICGC;COSMIC;GDSC;CCLE	7.780	Loss
AGC_Akt_AKT1_ST	Q86TI0	TBC1D1	P31749	AKT1	S1154	E1157V	1157	Missense	distal	3	no	11.797	11.748	EPSD	TCGA;ICGC;COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	Q86TI0	TBC1D1	P31749	AKT1	S1154	R1147W	1147	Missense	distal	-7	no	11.797	11.374	EPSD	TCGA;ICGC;COSMIC;GDSC;CCLE	7.780	Down-regulation
AGC_Akt_AKT1_ST	Q9Y2I7	PIKFYVE	P31749	AKT1	T22	R19Q	19	Missense	distal	-3	no	10.847	3.636	EPSD	TCGA;ICGC;COSMIC	7.780	Loss
AGC_Akt_AKT1_ST	Q9Y2I7	PIKFYVE	P31749	AKT1	S85	Q78E	78	Missense	distal	-7	no	12.329	12.317	EPSD	TCGA;ICGC;COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	Q9Y2I7	PIKFYVE	P31749	AKT1	S105	S104C	104	Missense	proximal	-1	no	10.955	10.895	EPSD	TCGA;ICGC;COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	Q9Y2I7	PIKFYVE	P31749	AKT1	S105	R103L	103	Missense	proximal	-2	no	10.955	10.287	EPSD	TCGA;ICGC;COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	Q9Y2I7	PIKFYVE	P31749	AKT1	S105	R111K	111	Missense	distal	6	no	10.955	10.967	EPSD	TCGA;ICGC;COSMIC	7.780	Up-regulation
AGC_Akt_AKT1_ST	Q9Y2I7	PIKFYVE	P31749	AKT1	S105	R103H	103	Missense	proximal	-2	no	10.955	10.094	EPSD	TCGA;ICGC;COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	Q9Y2I7	PIKFYVE	P31749	AKT1	S132	L131F	131	Missense	proximal	-1	no	11.907	11.901	EPSD	TCGA;ICGC;COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	Q9Y2I7	PIKFYVE	P31749	AKT1	S132	R129Q	129	Missense	distal	-3	no	11.907	4.696	EPSD	TCGA;ICGC;COSMIC	7.780	Loss
AGC_Akt_AKT1_ST	Q9Y2I7	PIKFYVE	P31749	AKT1	S132	R137H	137	Missense	distal	5	no	11.907	11.833	EPSD	TCGA;ICGC;COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	Q9Y2I7	PIKFYVE	P31749	AKT1	S219	L218S	218	Missense	proximal	-1	no	9.673	9.702	EPSD	TCGA	7.780	Up-regulation
AGC_Akt_AKT1_ST	Q9Y2I7	PIKFYVE	P31749	AKT1	S219	A221S	221	Missense	proximal	2	no	9.673	10.049	EPSD	TCGA;ICGC;COSMIC	7.780	Up-regulation
AGC_Akt_AKT1_ST	Q9Y2I7	PIKFYVE	P31749	AKT1	S219	D225Y	225	Missense	distal	6	no	9.673	9.734	EPSD	TCGA;ICGC;COSMIC	7.780	Up-regulation
AGC_Akt_AKT1_ST	Q9Y2I7	PIKFYVE	P31749	AKT1	S219	K215Q	215	Missense	distal	-4	no	9.673	9.066	EPSD	TCGA;ICGC;COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	Q9Y2I7	PIKFYVE	P31749	AKT1	S261	R262H	262	Missense	proximal	1	no	13.076	12.753	EPSD	TCGA;ICGC	7.780	Down-regulation
AGC_Akt_AKT1_ST	Q9Y2I7	PIKFYVE	P31749	AKT1	S291	V290A	290	Missense	proximal	-1	no	11.762	11.776	EPSD	TCGA;ICGC;COSMIC;GDSC	7.780	Up-regulation
AGC_Akt_AKT1_ST	Q9Y2I7	PIKFYVE	P31749	AKT1	S305	S299F	299	Missense	distal	-6	no	11.406	11.331	EPSD	TCGA;ICGC;COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	Q9Y2I7	PIKFYVE	P31749	AKT1	S305	S305L	305	Missense	central	0	yes	11.406	0.000	EPSD	TCGA;ICGC;COSMIC	7.780	Loss
AGC_Akt_AKT1_ST	Q9Y2I7	PIKFYVE	P31749	AKT1	S305	A306T	306	Missense	proximal	1	no	11.406	11.673	EPSD	TCGA;ICGC;COSMIC	7.780	Up-regulation
AGC_Akt_AKT1_ST	Q9Y2I7	PIKFYVE	P31749	AKT1	S307	S305L	305	Missense	proximal	-2	no	16.554	15.697	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	Q9Y2I7	PIKFYVE	P31749	AKT1	S307	A306T	306	Missense	proximal	-1	no	16.554	16.581	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	7.780	Up-regulation
AGC_Akt_AKT1_ST	Q9Y2I7	PIKFYVE	P31749	AKT1	T309	S305L	305	Missense	distal	-4	no	8.235	7.111	EPSD	TCGA;ICGC;COSMIC	7.780	Loss
AGC_Akt_AKT1_ST	Q9Y2I7	PIKFYVE	P31749	AKT1	T309	A306T	306	Missense	distal	-3	no	8.235	7.516	EPSD	TCGA;ICGC;COSMIC	7.780	Loss
AGC_Akt_AKT1_ST	Q9Y2I7	PIKFYVE	P31749	AKT1	T341	R334Q	334	Missense	distal	-7	no	9.937	9.743	EPSD	TCGA;ICGC	7.780	Down-regulation
AGC_Akt_AKT1_ST	Q9Y2I7	PIKFYVE	P31749	AKT1	S845	I839V	839	Missense	distal	-6	no	13.120	13.165	EPSD	TCGA;ICGC;COSMIC	7.780	Up-regulation
AGC_Akt_AKT1_ST	Q9Y2I7	PIKFYVE	P31749	AKT1	S845	D846G	846	Missense	proximal	1	no	13.120	13.028	EPSD	TCGA;ICGC;COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	Q9Y2I7	PIKFYVE	P31749	AKT1	S1042	Q1047E	1047	Missense	distal	5	no	9.279	9.290	EPSD	TCGA;ICGC;COSMIC	7.780	Up-regulation
AGC_Akt_AKT1_ST	Q9Y2I7	PIKFYVE	P31749	AKT1	S1042	K1039N	1039	Missense	distal	-3	no	9.279	6.323	EPSD	TCGA;COSMIC	7.780	Loss
AGC_Akt_AKT1_ST	Q9Y2I7	PIKFYVE	P31749	AKT1	S1042	R1038Q	1038	Missense	distal	-4	no	9.279	8.658	EPSD	TCGA;ICGC;COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	Q9Y2I7	PIKFYVE	P31749	AKT1	S1111	L1110V	1110	Missense	proximal	-1	no	9.608	9.602	EPSD	TCGA;ICGC;COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	Q9Y2I7	PIKFYVE	P31749	AKT1	S1111	S1111C	1111	Missense	central	0	yes	9.608	0.000	EPSD	TCGA;ICGC;COSMIC	7.780	Loss
AGC_Akt_AKT1_ST	Q9Y2I7	PIKFYVE	P31749	AKT1	S1111	D1109Y	1109	Missense	proximal	-2	no	9.608	10.079	EPSD	TCGA;ICGC	7.780	Up-regulation
AGC_Akt_AKT1_ST	Q9Y2I7	PIKFYVE	P31749	AKT1	S1177	K1174R	1174	Missense	distal	-3	no	7.207	11.728	EPSD	TCGA;ICGC;COSMIC	7.780	Gain
AGC_Akt_AKT1_ST	Q9Y2I7	PIKFYVE	P31749	AKT1	S1440	S1433F	1433	Missense	distal	-7	no	7.968	7.690	EPSD	TCGA;ICGC;COSMIC	7.780	Loss
AGC_Akt_AKT1_ST	Q9Y2I7	PIKFYVE	P31749	AKT1	S1440	T1438A	1438	Missense	proximal	-2	no	7.968	7.582	EPSD	TCGA;ICGC;COSMIC	7.780	Loss
AGC_Akt_AKT1_ST	Q9Y2I7	PIKFYVE	P31749	AKT1	S1440	T1442S	1442	Missense	proximal	2	no	7.968	8.042	EPSD	TCGA;ICGC;COSMIC	7.780	Up-regulation
AGC_Akt_AKT1_ST	Q9Y2I7	PIKFYVE	P31749	AKT1	S1474	S1476C	1476	Missense	proximal	2	no	12.258	11.433	EPSD	TCGA;ICGC;COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	Q9Y2I7	PIKFYVE	P31749	AKT1	S1474	Q1469H	1469	Missense	distal	-5	no	12.258	13.390	EPSD	TCGA;ICGC;COSMIC	7.780	Up-regulation
AGC_Akt_AKT1_ST	Q9Y2I7	PIKFYVE	P31749	AKT1	S1549	P1545S	1545	Missense	distal	-4	no	8.626	9.363	EPSD	TCGA;ICGC;COSMIC	7.780	Up-regulation
AGC_Akt_AKT1_ST	Q9Y2I7	PIKFYVE	P31749	AKT1	S1712	P1719L	1719	Missense	distal	7	no	12.049	12.041	EPSD	TCGA;ICGC;COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	Q9Y2I7	PIKFYVE	P31749	AKT1	S1714	P1719L	1719	Missense	distal	5	no	9.500	9.486	EPSD	TCGA;ICGC;COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	Q9Y2I7	PIKFYVE	P31749	AKT1	S1722	P1719L	1719	Missense	distal	-3	no	8.985	8.631	EPSD	TCGA;ICGC;COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	Q9Y2I7	PIKFYVE	P31749	AKT1	S1722	R1728C	1728	Missense	distal	6	no	8.985	8.783	EPSD	TCGA;ICGC;COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	Q9Y2I7	PIKFYVE	P31749	AKT1	S2004	I2002M	2002	Missense	proximal	-2	no	7.652	8.053	EPSD	TCGA;ICGC;COSMIC	7.780	Gain
AGC_Akt_AKT1_ST	Q9Y4P1	ATG4B	P31749	AKT1	S34	Y33H	33	Missense	proximal	-1	no	11.739	11.731	PhosphoSitePlus	TCGA;ICGC;COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	Q9Y4P1	ATG4B	P31749	AKT1	S383	R379I	379	Missense	distal	-4	no	8.846	7.378	EPSD	TCGA;COSMIC	7.780	Loss
AGC_Akt_AKT1_ST	Q9Y4P1	ATG4B	P31749	AKT1	S383	D382Y	382	Missense	proximal	-1	no	8.846	8.868	EPSD	TCGA	7.780	Up-regulation
AGC_Akt_AKT1_ST	Q9Y4P1	ATG4B	P31749	AKT1	S383	D382E	382	Missense	proximal	-1	no	8.846	8.879	EPSD	TCGA	7.780	Up-regulation
AGC_Akt_AKT1_ST	Q6R327	RICTOR	P31749	AKT1	S21	R18L	18	Missense	distal	-3	no	15.434	8.440	EPSD	TCGA;ICGC;COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	Q6R327	RICTOR	P31749	AKT1	S35	D36N	36	Missense	proximal	1	no	10.036	10.160	EPSD	TCGA;ICGC;COSMIC	7.780	Up-regulation
AGC_Akt_AKT1_ST	Q6R327	RICTOR	P31749	AKT1	S35	L42F	42	Missense	distal	7	no	10.036	10.028	EPSD	TCGA;ICGC;COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	Q6R327	RICTOR	P31749	AKT1	S35	E40K	40	Missense	distal	5	no	10.036	10.070	EPSD	TCGA;ICGC;COSMIC	7.780	Up-regulation
AGC_Akt_AKT1_ST	Q6R327	RICTOR	P31749	AKT1	S35	L30V	30	Missense	distal	-5	no	10.036	9.847	EPSD	TCGA;ICGC;COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	Q6R327	RICTOR	P31749	AKT1	S383	H379R	379	Missense	distal	-4	no	13.047	14.106	EPSD	TCGA;ICGC;COSMIC	7.780	Up-regulation
AGC_Akt_AKT1_ST	Q6R327	RICTOR	P31749	AKT1	S383	R380H	380	Missense	distal	-3	no	13.047	8.348	EPSD	TCGA;ICGC;COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	Q6R327	RICTOR	P31749	AKT1	S810	R807I	807	Missense	distal	-3	no	9.152	2.071	EPSD	TCGA;COSMIC	7.780	Loss
AGC_Akt_AKT1_ST	Q6R327	RICTOR	P31749	AKT1	S1035	S1042L	1042	Missense	distal	7	no	11.352	11.286	EPSD	TCGA;ICGC;COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	Q6R327	RICTOR	P31749	AKT1	S1035	E1038G	1038	Missense	distal	3	no	11.352	11.302	EPSD	TCGA;ICGC;COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	Q6R327	RICTOR	P31749	AKT1	S1037	S1042L	1042	Missense	distal	5	no	9.015	8.949	EPSD	TCGA;ICGC;COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	Q6R327	RICTOR	P31749	AKT1	S1037	E1038G	1038	Missense	proximal	1	no	9.015	8.806	EPSD	TCGA;ICGC;COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	Q6R327	RICTOR	P31749	AKT1	T1133	T1135M	1135	Missense	proximal	2	no	10.556	10.214	EPSD	TCGA;ICGC;COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	Q6R327	RICTOR	P31749	AKT1	T1133	R1130Q	1130	Missense	distal	-3	no	10.556	3.345	EPSD	TCGA;ICGC;COSMIC;GDSC;CCLE	7.780	Loss
AGC_Akt_AKT1_ST	Q6R327	RICTOR	P31749	AKT1	T1135	T1135M	1135	Missense	central	0	yes	13.824	0.000	PhosphoSitePlus	TCGA;ICGC;COSMIC	7.780	Loss
AGC_Akt_AKT1_ST	Q6R327	RICTOR	P31749	AKT1	T1135	R1130Q	1130	Missense	distal	-5	no	13.824	9.597	PhosphoSitePlus	TCGA;ICGC;COSMIC;GDSC;CCLE	7.780	Down-regulation
AGC_Akt_AKT1_ST	Q6R327	RICTOR	P31749	AKT1	T1198	E1196Q	1196	Missense	proximal	-2	no	8.944	8.652	EPSD	TCGA;ICGC;COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	Q6R327	RICTOR	P31749	AKT1	T1198	R1200Q	1200	Missense	proximal	2	no	8.944	8.827	EPSD	TCGA;ICGC;COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	Q6R327	RICTOR	P31749	AKT1	S1219	T1222I	1222	Missense	distal	3	no	11.267	11.137	EPSD	TCGA;ICGC;COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	Q6R327	RICTOR	P31749	AKT1	S1219	R1216H	1216	Missense	distal	-3	no	11.267	6.568	EPSD	TCGA;ICGC;COSMIC;CCLE	7.780	Loss
AGC_Akt_AKT1_ST	Q6R327	RICTOR	P31749	AKT1	S1302	R1299G	1299	Missense	distal	-3	no	13.316	6.560	EPSD	TCGA;ICGC;COSMIC	7.780	Loss
AGC_Akt_AKT1_ST	Q6R327	RICTOR	P31749	AKT1	S1302	A1305S	1305	Missense	distal	3	no	13.316	13.374	EPSD	TCGA;ICGC;COSMIC	7.780	Up-regulation
AGC_Akt_AKT1_ST	Q6R327	RICTOR	P31749	AKT1	S1408	S1407F	1407	Missense	proximal	-1	no	14.254	14.219	EPSD	TCGA;ICGC;COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	Q6R327	RICTOR	P31749	AKT1	S1408	R1405Q	1405	Missense	distal	-3	no	14.254	7.043	EPSD	TCGA;ICGC;COSMIC	7.780	Loss
AGC_Akt_AKT1_ST	Q6R327	RICTOR	P31749	AKT1	S1415	G1420C	1420	Missense	distal	5	no	8.908	8.852	EPSD	TCGA;ICGC;COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	Q6R327	RICTOR	P31749	AKT1	S1415	A1416V	1416	Missense	proximal	1	no	8.908	8.980	EPSD	TCGA;ICGC;COSMIC	7.780	Up-regulation
AGC_Akt_AKT1_ST	Q6R327	RICTOR	P31749	AKT1	S1415	S1421P	1421	Missense	distal	6	no	8.908	8.814	EPSD	TCGA;ICGC;COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	P45985	MAP2K4	P31749	AKT1	T78	S80N	80	Missense	proximal	2	no	10.970	10.701	EPSD	TCGA;COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	P45985	MAP2K4	P31749	AKT1	T78	S83A	83	Missense	distal	5	no	10.970	10.919	EPSD	TCGA	7.780	Down-regulation
AGC_Akt_AKT1_ST	P45985	MAP2K4	P31749	AKT1	S80	S80N	80	Missense	central	0	yes	16.956	0.000	PhosphoSitePlus	TCGA;COSMIC	7.780	Loss
AGC_Akt_AKT1_ST	P45985	MAP2K4	P31749	AKT1	S80	S83A	83	Missense	distal	3	no	16.956	16.898	PhosphoSitePlus	TCGA	7.780	Down-regulation
AGC_Akt_AKT1_ST	P45985	MAP2K4	P31749	AKT1	S292	W291C	291	Missense	proximal	-1	no	9.191	9.182	EPSD	TCGA;COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	P45985	MAP2K4	P31749	AKT1	S292	R287H	287	Missense	distal	-5	no	9.191	6.097	EPSD	TCGA;COSMIC	7.780	Loss
AGC_Akt_AKT1_ST	Q96CG3	TIFA	P31749	AKT1	S174	P176R	176	Missense	proximal	2	no	8.143	8.307	EPSD	TCGA;ICGC;COSMIC	7.780	Up-regulation
AGC_Akt_AKT1_ST	Q96CG3	TIFA	P31749	AKT1	S174	S175Y	175	Missense	proximal	1	no	8.143	8.135	EPSD	TCGA;ICGC;COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	Q96CG3	TIFA	P31749	AKT1	S175	P176R	176	Missense	proximal	1	no	7.812	8.112	EPSD	TCGA;ICGC;COSMIC	7.780	Up-regulation
AGC_Akt_AKT1_ST	Q96CG3	TIFA	P31749	AKT1	S175	S175Y	175	Missense	central	0	yes	7.812	0.000	EPSD	TCGA;ICGC;COSMIC	7.780	Loss
AGC_Akt_AKT1_ST	Q8WX93	PALLD	P31749	AKT1	S13	E8Q	8	Missense	distal	-5	no	8.762	8.630	EPSD	TCGA;ICGC;COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	Q8WX93	PALLD	P31749	AKT1	S125	S132N	132	Missense	distal	7	no	8.726	8.690	EPSD	TCGA;COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	Q8WX93	PALLD	P31749	AKT1	S125	P126L	126	Missense	proximal	1	no	8.726	8.980	EPSD	TCGA;COSMIC	7.780	Up-regulation
AGC_Akt_AKT1_ST	Q8WX93	PALLD	P31749	AKT1	T147	G144R	144	Missense	distal	-3	no	7.349	14.105	EPSD	TCGA;COSMIC	7.780	Gain
AGC_Akt_AKT1_ST	Q8WX93	PALLD	P31749	AKT1	S192	R189T	189	Missense	distal	-3	no	12.748	5.727	EPSD	TCGA;COSMIC	7.780	Loss
AGC_Akt_AKT1_ST	Q8WX93	PALLD	P31749	AKT1	S356	E362Q	362	Missense	distal	6	no	7.847	7.834	EPSD	TCGA;COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	Q8WX93	PALLD	P31749	AKT1	S356	E358D	358	Missense	proximal	2	no	7.847	7.437	EPSD	TCGA;COSMIC	7.780	Loss
AGC_Akt_AKT1_ST	Q8WX93	PALLD	P31749	AKT1	S356	S350R	350	Missense	distal	-6	no	7.847	7.881	EPSD	TCGA;COSMIC	7.780	Up-regulation
AGC_Akt_AKT1_ST	Q8WX93	PALLD	P31749	AKT1	S356	A357S	357	Missense	proximal	1	no	7.847	7.921	EPSD	TCGA;COSMIC	7.780	Up-regulation
AGC_Akt_AKT1_ST	Q8WX93	PALLD	P31749	AKT1	S356	P349L	349	Missense	distal	-7	no	7.847	7.807	EPSD	TCGA;COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	Q8WX93	PALLD	P31749	AKT1	S394	G398R	398	Missense	distal	4	no	8.071	7.909	EPSD	TCGA;COSMIC;CCLE	7.780	Down-regulation
AGC_Akt_AKT1_ST	Q8WX93	PALLD	P31749	AKT1	S401	G398R	398	Missense	distal	-3	no	4.879	11.635	EPSD	TCGA;COSMIC;CCLE	7.780	Gain
AGC_Akt_AKT1_ST	Q8WX93	PALLD	P31749	AKT1	S479	R476W	476	Missense	distal	-3	no	8.089	-0.851	EPSD	TCGA;COSMIC	7.780	Loss
AGC_Akt_AKT1_ST	Q8WX93	PALLD	P31749	AKT1	S479	R476Q	476	Missense	distal	-3	no	8.089	0.878	EPSD	TCGA;COSMIC	7.780	Loss
AGC_Akt_AKT1_ST	Q8WX93	PALLD	P31749	AKT1	S479	S484F	484	Missense	distal	5	no	8.089	8.017	EPSD	TCGA;COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	Q8WX93	PALLD	P31749	AKT1	S582	K579R	579	Missense	distal	-3	no	7.694	12.214	EPSD	TCGA;ICGC;COSMIC	7.780	Gain
AGC_Akt_AKT1_ST	Q8WX93	PALLD	P31749	AKT1	T643	L640R	640	Missense	distal	-3	no	3.191	10.185	EPSD	TCGA;ICGC	7.780	Gain
AGC_Akt_AKT1_ST	Q7Z6J0	SH3RF1	P31749	AKT1	S58	S58L	58	Missense	central	0	yes	8.450	0.000	EPSD	TCGA;ICGC;COSMIC	7.780	Loss
AGC_Akt_AKT1_ST	Q7Z6J0	SH3RF1	P31749	AKT1	S58	E51K	51	Missense	distal	-7	no	8.450	8.643	EPSD	TCGA;ICGC;COSMIC	7.780	Up-regulation
AGC_Akt_AKT1_ST	Q7Z6J0	SH3RF1	P31749	AKT1	S125	G132R	132	Missense	distal	7	no	10.727	10.807	EPSD	TCGA;ICGC;COSMIC	7.780	Up-regulation
AGC_Akt_AKT1_ST	Q7Z6J0	SH3RF1	P31749	AKT1	S125	R122L	122	Missense	distal	-3	no	10.727	3.733	EPSD	TCGA;ICGC;COSMIC	7.780	Loss
AGC_Akt_AKT1_ST	Q7Z6J0	SH3RF1	P31749	AKT1	S125	G132S	132	Missense	distal	7	no	10.727	10.800	EPSD	TCGA;ICGC;COSMIC	7.780	Up-regulation
AGC_Akt_AKT1_ST	Q7Z6J0	SH3RF1	P31749	AKT1	S125	R122Q	122	Missense	distal	-3	no	10.727	3.515	EPSD	TCGA;ICGC;COSMIC	7.780	Loss
AGC_Akt_AKT1_ST	Q7Z6J0	SH3RF1	P31749	AKT1	S304	R302W	302	Missense	proximal	-2	no	10.102	8.848	PhosphoSitePlus	TCGA;ICGC;COSMIC;CCLE	7.780	Down-regulation
AGC_Akt_AKT1_ST	Q7Z6J0	SH3RF1	P31749	AKT1	S304	S307F	307	Missense	distal	3	no	10.102	10.004	PhosphoSitePlus	TCGA;ICGC;COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	Q7Z6J0	SH3RF1	P31749	AKT1	T306	R302W	302	Missense	distal	-4	no	8.492	6.943	EPSD	TCGA;ICGC;COSMIC;CCLE	7.780	Loss
AGC_Akt_AKT1_ST	Q7Z6J0	SH3RF1	P31749	AKT1	T306	S307F	307	Missense	proximal	1	no	8.492	8.510	EPSD	TCGA;ICGC;COSMIC	7.780	Up-regulation
AGC_Akt_AKT1_ST	Q7Z6J0	SH3RF1	P31749	AKT1	T509	V508M	508	Missense	proximal	-1	no	10.462	10.468	EPSD	TCGA;ICGC;COSMIC	7.780	Up-regulation
AGC_Akt_AKT1_ST	Q7Z6J0	SH3RF1	P31749	AKT1	T529	Q523H	523	Missense	distal	-6	no	11.455	11.420	EPSD	TCGA;ICGC;COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	Q7Z6J0	SH3RF1	P31749	AKT1	T567	H564R	564	Missense	distal	-3	no	4.750	9.449	EPSD	TCGA;ICGC;COSMIC	7.780	Gain
AGC_Akt_AKT1_ST	Q7Z6J0	SH3RF1	P31749	AKT1	T684	P678S	678	Missense	distal	-6	no	9.469	9.533	EPSD	TCGA	7.780	Up-regulation
AGC_Akt_AKT1_ST	Q7Z6J0	SH3RF1	P31749	AKT1	S735	S739L	739	Missense	distal	4	no	10.577	10.765	EPSD	TCGA;ICGC;COSMIC	7.780	Up-regulation
AGC_Akt_AKT1_ST	Q7Z6J0	SH3RF1	P31749	AKT1	S735	K731T	731	Missense	distal	-4	no	10.577	10.561	EPSD	TCGA;ICGC;COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	Q7Z6J0	SH3RF1	P31749	AKT1	S735	R730W	730	Missense	distal	-5	no	10.577	5.057	EPSD	TCGA;ICGC;COSMIC	7.780	Loss
AGC_Akt_AKT1_ST	Q7Z6J0	SH3RF1	P31749	AKT1	S735	P732S	732	Missense	distal	-3	no	10.577	9.440	EPSD	TCGA;ICGC;COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	Q7Z6J0	SH3RF1	P31749	AKT1	S735	R733H	733	Missense	proximal	-2	no	10.577	9.716	EPSD	TCGA;ICGC	7.780	Down-regulation
AGC_Akt_AKT1_ST	Q7Z6J0	SH3RF1	P31749	AKT1	S772	S772Y	772	Missense	central	0	yes	12.049	0.000	EPSD	TCGA;ICGC;COSMIC	7.780	Loss
AGC_Akt_AKT1_ST	Q7Z6J0	SH3RF1	P31749	AKT1	S772	S772F	772	Missense	central	0	yes	12.049	0.000	EPSD	TCGA;ICGC;COSMIC;CCLE	7.780	Loss
AGC_Akt_AKT1_ST	Q7Z6J0	SH3RF1	P31749	AKT1	S772	R769M	769	Missense	distal	-3	no	12.049	4.543	EPSD	TCGA;ICGC;COSMIC	7.780	Loss
AGC_Akt_AKT1_ST	Q7Z6J0	SH3RF1	P31749	AKT1	S800	P807S	807	Missense	distal	7	no	12.055	12.113	EPSD	TCGA;ICGC;COSMIC	7.780	Up-regulation
AGC_Akt_AKT1_ST	Q7Z6J0	SH3RF1	P31749	AKT1	S800	S801F	801	Missense	proximal	1	no	12.055	12.073	EPSD	TCGA;ICGC;COSMIC	7.780	Up-regulation
AGC_Akt_AKT1_ST	Q7Z6J0	SH3RF1	P31749	AKT1	S818	L823F	823	Missense	distal	5	no	8.748	8.742	EPSD	TCGA;ICGC;COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	Q7Z6J0	SH3RF1	P31749	AKT1	S818	P821S	821	Missense	distal	3	no	8.748	8.830	EPSD	TCGA;ICGC;COSMIC	7.780	Up-regulation
AGC_Akt_AKT1_ST	Q7Z6J0	SH3RF1	P31749	AKT1	S818	P812S	812	Missense	distal	-6	no	8.748	8.813	EPSD	TCGA;ICGC;COSMIC	7.780	Up-regulation
AGC_Akt_AKT1_ST	Q8NCD3	HJURP	P31749	AKT1	S201	K200N	200	Missense	proximal	-1	no	8.190	8.165	EPSD	TCGA;ICGC;COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	Q8NCD3	HJURP	P31749	AKT1	S201	K200E	200	Missense	proximal	-1	no	8.190	8.169	EPSD	TCGA;COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	Q8NCD3	HJURP	P31749	AKT1	S201	I197M	197	Missense	distal	-4	no	8.190	8.662	EPSD	TCGA	7.780	Up-regulation
AGC_Akt_AKT1_ST	Q8NCD3	HJURP	P31749	AKT1	S276	R273W	273	Missense	distal	-3	no	11.646	2.706	EPSD	TCGA;ICGC;COSMIC	7.780	Loss
AGC_Akt_AKT1_ST	Q8NCD3	HJURP	P31749	AKT1	S276	I282V	282	Missense	distal	6	no	11.646	11.697	EPSD	TCGA;COSMIC	7.780	Up-regulation
AGC_Akt_AKT1_ST	Q8NCD3	HJURP	P31749	AKT1	S276	I283M	283	Missense	distal	7	no	11.646	11.685	EPSD	TCGA	7.780	Up-regulation
AGC_Akt_AKT1_ST	Q8NCD3	HJURP	P31749	AKT1	T380	V379M	379	Missense	proximal	-1	no	12.598	12.604	EPSD	TCGA;COSMIC	7.780	Up-regulation
AGC_Akt_AKT1_ST	Q8NCD3	HJURP	P31749	AKT1	T380	L387F	387	Missense	distal	7	no	12.598	12.591	EPSD	TCGA;COSMIC;CCLE	7.780	Down-regulation
AGC_Akt_AKT1_ST	Q8NCD3	HJURP	P31749	AKT1	S382	V379M	379	Missense	distal	-3	no	10.087	9.447	EPSD	TCGA;COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	Q8NCD3	HJURP	P31749	AKT1	S382	L387F	387	Missense	distal	5	no	10.087	10.081	EPSD	TCGA;COSMIC;CCLE	7.780	Down-regulation
AGC_Akt_AKT1_ST	Q8NCD3	HJURP	P31749	AKT1	S486	T482P	482	Missense	distal	-4	no	13.501	12.708	PhosphoSitePlus	TCGA;ICGC;COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	Q8NCD3	HJURP	P31749	AKT1	S486	P488L	488	Missense	proximal	2	no	13.501	13.291	PhosphoSitePlus	TCGA;ICGC;COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	Q8NCD3	HJURP	P31749	AKT1	S486	R483H	483	Missense	distal	-3	no	13.501	8.802	PhosphoSitePlus	TCGA;ICGC;COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	Q8NCD3	HJURP	P31749	AKT1	S486	K493R	493	Missense	distal	7	no	13.501	13.508	PhosphoSitePlus	TCGA;COSMIC	7.780	Up-regulation
AGC_Akt_AKT1_ST	Q8NCD3	HJURP	P31749	AKT1	S489	T482P	482	Missense	distal	-7	no	8.222	7.978	EPSD	TCGA;ICGC;COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	Q8NCD3	HJURP	P31749	AKT1	S489	P488L	488	Missense	proximal	-1	no	8.222	8.223	EPSD	TCGA;ICGC;COSMIC	7.780	Up-regulation
AGC_Akt_AKT1_ST	Q8NCD3	HJURP	P31749	AKT1	S489	R483H	483	Missense	distal	-6	no	8.222	8.104	EPSD	TCGA;ICGC;COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	Q8NCD3	HJURP	P31749	AKT1	S489	K493R	493	Missense	distal	4	no	8.222	8.256	EPSD	TCGA;COSMIC	7.780	Up-regulation
AGC_Akt_AKT1_ST	Q8NCD3	HJURP	P31749	AKT1	S496	E502K	502	Missense	distal	6	no	8.578	8.647	EPSD	TCGA;ICGC;COSMIC	7.780	Up-regulation
AGC_Akt_AKT1_ST	Q8NCD3	HJURP	P31749	AKT1	S496	K493R	493	Missense	distal	-3	no	8.578	13.098	EPSD	TCGA;COSMIC	7.780	Up-regulation
AGC_Akt_AKT1_ST	Q8NCD3	HJURP	P31749	AKT1	S498	E502K	502	Missense	distal	4	no	10.479	10.378	EPSD	TCGA;ICGC;COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	Q8NCD3	HJURP	P31749	AKT1	S498	K493R	493	Missense	distal	-5	no	10.479	12.876	EPSD	TCGA;COSMIC	7.780	Up-regulation
AGC_Akt_AKT1_ST	Q8NCD3	HJURP	P31749	AKT1	S557	I551V	551	Missense	distal	-6	no	9.611	9.656	EPSD	TCGA	7.780	Up-regulation
AGC_Akt_AKT1_ST	Q8NCD3	HJURP	P31749	AKT1	S563	P565S	565	Missense	proximal	2	no	7.562	7.898	EPSD	TCGA;ICGC;COSMIC	7.780	Gain
AGC_Akt_AKT1_ST	Q8NCD3	HJURP	P31749	AKT1	S686	P688S	688	Missense	proximal	2	no	7.547	7.883	EPSD	TCGA;COSMIC	7.780	Gain
AGC_Akt_AKT1_ST	Q8NCD3	HJURP	P31749	AKT1	S736	R731S	731	Missense	distal	-5	no	11.394	6.923	EPSD	TCGA;ICGC;COSMIC	7.780	Loss
AGC_Akt_AKT1_ST	Q8NCD3	HJURP	P31749	AKT1	S736	E734Q	734	Missense	proximal	-2	no	11.394	11.101	EPSD	TCGA;COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	P35568	IRS1	P31749	AKT1	S36	E37K	37	Missense	proximal	1	no	9.585	9.748	EPSD	TCGA;ICGC;COSMIC;GDSC;CCLE	7.780	Up-regulation
AGC_Akt_AKT1_ST	P35568	IRS1	P31749	AKT1	S36	A42V	42	Missense	distal	6	no	9.585	9.553	EPSD	TCGA;ICGC;COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	P35568	IRS1	P31749	AKT1	S36	A42T	42	Missense	distal	6	no	9.585	9.688	EPSD	TCGA;ICGC;COSMIC	7.780	Up-regulation
AGC_Akt_AKT1_ST	P35568	IRS1	P31749	AKT1	S36	S36N	36	Missense	central	0	yes	9.585	0.000	EPSD	TCGA;ICGC;COSMIC	7.780	Loss
AGC_Akt_AKT1_ST	P35568	IRS1	P31749	AKT1	S36	R33C	33	Missense	distal	-3	no	9.585	3.411	EPSD	TCGA;ICGC;COSMIC	7.780	Loss
AGC_Akt_AKT1_ST	P35568	IRS1	P31749	AKT1	S189	I182V	182	Missense	distal	-7	no	9.152	9.247	EPSD	TCGA;ICGC	7.780	Up-regulation
AGC_Akt_AKT1_ST	P35568	IRS1	P31749	AKT1	S189	V195M	195	Missense	distal	6	no	9.152	9.167	EPSD	TCGA;ICGC;COSMIC	7.780	Up-regulation
AGC_Akt_AKT1_ST	P35568	IRS1	P31749	AKT1	S189	L185R	185	Missense	distal	-4	no	9.152	10.362	EPSD	TCGA;ICGC;COSMIC	7.780	Up-regulation
AGC_Akt_AKT1_ST	P35568	IRS1	P31749	AKT1	S193	V195M	195	Missense	proximal	2	no	9.594	9.716	EPSD	TCGA;ICGC;COSMIC	7.780	Up-regulation
AGC_Akt_AKT1_ST	P35568	IRS1	P31749	AKT1	S268	E263K	263	Missense	distal	-5	no	11.282	12.979	EPSD	TCGA;ICGC;COSMIC	7.780	Up-regulation
AGC_Akt_AKT1_ST	P35568	IRS1	P31749	AKT1	S268	K269N	269	Missense	proximal	1	no	11.282	11.125	EPSD	TCGA;ICGC;COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	P35568	IRS1	P31749	AKT1	S268	P266S	266	Missense	proximal	-2	no	11.282	12.106	EPSD	TCGA;ICGC;COSMIC	7.780	Up-regulation
AGC_Akt_AKT1_ST	P35568	IRS1	P31749	AKT1	S268	S261I	261	Missense	distal	-7	no	11.282	10.909	EPSD	TCGA;ICGC;COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	P35568	IRS1	P31749	AKT1	S268	N275S	275	Missense	distal	7	no	11.282	11.317	EPSD	TCGA;ICGC;COSMIC	7.780	Up-regulation
AGC_Akt_AKT1_ST	P35568	IRS1	P31749	AKT1	S270	E263K	263	Missense	distal	-7	no	14.918	15.111	EPSD	TCGA;ICGC;COSMIC	7.780	Up-regulation
AGC_Akt_AKT1_ST	P35568	IRS1	P31749	AKT1	S270	K269N	269	Missense	proximal	-1	no	14.918	14.893	EPSD	TCGA;ICGC;COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	P35568	IRS1	P31749	AKT1	S270	P266S	266	Missense	distal	-4	no	14.918	15.654	EPSD	TCGA;ICGC;COSMIC	7.780	Up-regulation
AGC_Akt_AKT1_ST	P35568	IRS1	P31749	AKT1	S270	C276F	276	Missense	distal	6	no	14.918	15.001	EPSD	TCGA;ICGC;COSMIC	7.780	Up-regulation
AGC_Akt_AKT1_ST	P35568	IRS1	P31749	AKT1	S270	N275S	275	Missense	distal	5	no	14.918	14.952	EPSD	TCGA;ICGC;COSMIC	7.780	Up-regulation
AGC_Akt_AKT1_ST	P35568	IRS1	P31749	AKT1	S272	K269N	269	Missense	distal	-3	no	12.914	9.958	EPSD	TCGA;ICGC;COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	P35568	IRS1	P31749	AKT1	S272	P266S	266	Missense	distal	-6	no	12.914	12.978	EPSD	TCGA;ICGC;COSMIC	7.780	Up-regulation
AGC_Akt_AKT1_ST	P35568	IRS1	P31749	AKT1	S272	C276F	276	Missense	distal	4	no	12.914	12.766	EPSD	TCGA;ICGC;COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	P35568	IRS1	P31749	AKT1	S272	N275S	275	Missense	distal	3	no	12.914	12.971	EPSD	TCGA;ICGC;COSMIC	7.780	Up-regulation
AGC_Akt_AKT1_ST	P35568	IRS1	P31749	AKT1	S307	A314G	314	Missense	distal	7	no	16.317	16.294	EPSD	TCGA;ICGC;COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	P35568	IRS1	P31749	AKT1	T309	A314G	314	Missense	distal	5	no	9.758	9.746	EPSD	TCGA;ICGC;COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	P35568	IRS1	P31749	AKT1	S330	R327H	327	Missense	distal	-3	no	14.092	9.394	EPSD	TCGA;ICGC	7.780	Down-regulation
AGC_Akt_AKT1_ST	P35568	IRS1	P31749	AKT1	S330	D331V	331	Missense	proximal	1	no	14.092	14.304	EPSD	TCGA;ICGC;COSMIC	7.780	Up-regulation
AGC_Akt_AKT1_ST	P35568	IRS1	P31749	AKT1	S330	T335I	335	Missense	distal	5	no	14.092	13.995	EPSD	TCGA;ICGC;COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	P35568	IRS1	P31749	AKT1	S330	A328T	328	Missense	proximal	-2	no	14.092	14.478	EPSD	TCGA;ICGC;COSMIC	7.780	Up-regulation
AGC_Akt_AKT1_ST	P35568	IRS1	P31749	AKT1	S330	S330N	330	Missense	central	0	yes	14.092	0.000	EPSD	TCGA;ICGC;COSMIC	7.780	Loss
AGC_Akt_AKT1_ST	P35568	IRS1	P31749	AKT1	S330	S323A	323	Missense	distal	-7	no	14.092	13.943	EPSD	TCGA;ICGC;COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	P35568	IRS1	P31749	AKT1	S341	T335I	335	Missense	distal	-6	no	10.756	10.605	EPSD	TCGA;ICGC;COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	P35568	IRS1	P31749	AKT1	S341	R338H	338	Missense	distal	-3	no	10.756	6.057	EPSD	TCGA;ICGC;COSMIC	7.780	Loss
AGC_Akt_AKT1_ST	P35568	IRS1	P31749	AKT1	S341	R338C	338	Missense	distal	-3	no	10.756	4.582	EPSD	TCGA;ICGC;COSMIC	7.780	Loss
AGC_Akt_AKT1_ST	P35568	IRS1	P31749	AKT1	S341	P346H	346	Missense	distal	5	no	10.756	10.742	EPSD	TCGA;ICGC	7.780	Down-regulation
AGC_Akt_AKT1_ST	P35568	IRS1	P31749	AKT1	S362	A363D	363	Missense	proximal	1	no	8.382	8.242	EPSD	TCGA;ICGC;COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	P35568	IRS1	P31749	AKT1	S362	A356T	356	Missense	distal	-6	no	8.382	8.468	EPSD	TCGA;ICGC;COSMIC	7.780	Up-regulation
AGC_Akt_AKT1_ST	P35568	IRS1	P31749	AKT1	S362	A363T	363	Missense	proximal	1	no	8.382	8.649	EPSD	TCGA;ICGC;COSMIC	7.780	Up-regulation
AGC_Akt_AKT1_ST	P35568	IRS1	P31749	AKT1	S362	R360W	360	Missense	proximal	-2	no	8.382	7.128	EPSD	TCGA;ICGC;CCLE	7.780	Loss
AGC_Akt_AKT1_ST	P35568	IRS1	P31749	AKT1	S362	H359R	359	Missense	distal	-3	no	8.382	13.081	EPSD	TCGA;ICGC	7.780	Up-regulation
AGC_Akt_AKT1_ST	P35568	IRS1	P31749	AKT1	S413	R411Q	411	Missense	proximal	-2	no	12.105	11.592	EPSD	TCGA;ICGC	7.780	Down-regulation
AGC_Akt_AKT1_ST	P35568	IRS1	P31749	AKT1	S415	R411Q	411	Missense	distal	-4	no	8.256	7.634	EPSD	TCGA;ICGC	7.780	Loss
AGC_Akt_AKT1_ST	P35568	IRS1	P31749	AKT1	S444	F438V	438	Missense	distal	-6	no	7.937	7.936	EPSD	TCGA;ICGC;COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	P35568	IRS1	P31749	AKT1	S444	V445I	445	Missense	proximal	1	no	7.937	7.690	EPSD	TCGA;ICGC;COSMIC	7.780	Loss
AGC_Akt_AKT1_ST	P35568	IRS1	P31749	AKT1	S444	R443H	443	Missense	proximal	-1	no	7.937	7.893	EPSD	TCGA;ICGC	7.780	Down-regulation
AGC_Akt_AKT1_ST	P35568	IRS1	P31749	AKT1	T446	V445I	445	Missense	proximal	-1	no	8.852	8.838	EPSD	TCGA;ICGC;COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	P35568	IRS1	P31749	AKT1	T446	R443H	443	Missense	distal	-3	no	8.852	4.153	EPSD	TCGA;ICGC	7.780	Loss
AGC_Akt_AKT1_ST	P35568	IRS1	P31749	AKT1	T525	R520W	520	Missense	distal	-5	no	14.903	9.383	EPSD	TCGA;ICGC;COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	P35568	IRS1	P31749	AKT1	T525	R522Q	522	Missense	distal	-3	no	14.903	7.692	EPSD	TCGA;ICGC;COSMIC	7.780	Loss
AGC_Akt_AKT1_ST	P35568	IRS1	P31749	AKT1	T525	R520Q	520	Missense	distal	-5	no	14.903	10.676	EPSD	TCGA;ICGC;COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	P35568	IRS1	P31749	AKT1	S527	R520W	520	Missense	distal	-7	no	16.468	16.045	EPSD	TCGA;ICGC;COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	P35568	IRS1	P31749	AKT1	S527	R522Q	522	Missense	distal	-5	no	16.468	12.241	EPSD	TCGA;ICGC;COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	P35568	IRS1	P31749	AKT1	S527	R520Q	520	Missense	distal	-7	no	16.468	16.274	EPSD	TCGA;ICGC;COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	P35568	IRS1	P31749	AKT1	S574	S581Y	581	Missense	distal	7	no	7.811	7.768	EPSD	TCGA;ICGC;COSMIC	7.780	Loss
AGC_Akt_AKT1_ST	P35568	IRS1	P31749	AKT1	S574	P569L	569	Missense	distal	-5	no	7.811	7.695	EPSD	TCGA;ICGC;COSMIC	7.780	Loss
AGC_Akt_AKT1_ST	P35568	IRS1	P31749	AKT1	S603	H607R	607	Missense	distal	4	no	12.032	11.847	EPSD	TCGA;ICGC	7.780	Down-regulation
AGC_Akt_AKT1_ST	P35568	IRS1	P31749	AKT1	S603	R600C	600	Missense	distal	-3	no	12.032	5.858	EPSD	TCGA;ICGC;COSMIC	7.780	Loss
AGC_Akt_AKT1_ST	P35568	IRS1	P31749	AKT1	T605	H607R	607	Missense	proximal	2	no	9.252	9.613	EPSD	TCGA;ICGC	7.780	Up-regulation
AGC_Akt_AKT1_ST	P35568	IRS1	P31749	AKT1	T605	G611C	611	Missense	distal	6	no	9.252	9.154	EPSD	TCGA;ICGC;COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	P35568	IRS1	P31749	AKT1	T605	R600C	600	Missense	distal	-5	no	9.252	5.175	EPSD	TCGA;ICGC;COSMIC	7.780	Loss
AGC_Akt_AKT1_ST	P35568	IRS1	P31749	AKT1	T793	R797C	797	Missense	distal	4	no	10.368	10.702	EPSD	TCGA;ICGC;COSMIC	7.780	Up-regulation
AGC_Akt_AKT1_ST	P35568	IRS1	P31749	AKT1	T859	A856T	856	Missense	distal	-3	no	8.975	8.257	EPSD	TCGA;ICGC;COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	P35568	IRS1	P31749	AKT1	T859	R857W	857	Missense	proximal	-2	no	8.975	7.721	EPSD	TCGA;ICGC;COSMIC	7.780	Loss
AGC_Akt_AKT1_ST	P35568	IRS1	P31749	AKT1	S862	A856T	856	Missense	distal	-6	no	8.757	8.843	EPSD	TCGA;ICGC;COSMIC	7.780	Up-regulation
AGC_Akt_AKT1_ST	P35568	IRS1	P31749	AKT1	S862	R857W	857	Missense	distal	-5	no	8.757	3.237	EPSD	TCGA;ICGC;COSMIC	7.780	Loss
AGC_Akt_AKT1_ST	P35568	IRS1	P31749	AKT1	S985	R986W	986	Missense	proximal	1	no	9.896	9.603	EPSD	TCGA;ICGC;COSMIC;GDSC;CCLE	7.780	Down-regulation
AGC_Akt_AKT1_ST	P35568	IRS1	P31749	AKT1	S1084	R1081H	1081	Missense	distal	-3	no	10.904	6.205	EPSD	TCGA;ICGC;COSMIC	7.780	Loss
AGC_Akt_AKT1_ST	P35568	IRS1	P31749	AKT1	S1084	R1089C	1089	Missense	distal	5	no	10.904	10.778	EPSD	TCGA;ICGC;COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	P35568	IRS1	P31749	AKT1	T1103	S1109C	1109	Missense	distal	6	no	7.892	7.689	EPSD	TCGA;ICGC;COSMIC	7.780	Loss
AGC_Akt_AKT1_ST	P35568	IRS1	P31749	AKT1	S1223	S1223G	1223	Missense	central	0	yes	13.710	0.000	EPSD	TCGA;ICGC;COSMIC	7.780	Loss
AGC_Akt_AKT1_ST	P35568	IRS1	P31749	AKT1	S1231	S1233G	1233	Missense	proximal	2	no	8.367	8.035	EPSD	TCGA;ICGC;COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	Q16875	PFKFB3	P31749	AKT1	S211	R208G	208	Missense	distal	-3	no	9.597	2.841	EPSD	TCGA;COSMIC	7.780	Loss
AGC_Akt_AKT1_ST	Q16875	PFKFB3	P31749	AKT1	S211	V218M	218	Missense	distal	7	no	9.597	9.593	EPSD	TCGA;ICGC;COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	Q16875	PFKFB3	P31749	AKT1	S280	S273N	273	Missense	distal	-7	no	8.046	7.931	EPSD	TCGA;ICGC;COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	Q16875	PFKFB3	P31749	AKT1	S280	G275C	275	Missense	distal	-5	no	8.046	8.033	EPSD	TCGA;ICGC;COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	Q16875	PFKFB3	P31749	AKT1	S446	R443W	443	Missense	distal	-3	no	10.569	1.629	EPSD	TCGA;ICGC;COSMIC;CCLE	7.780	Loss
AGC_Akt_AKT1_ST	Q16875	PFKFB3	P31749	AKT1	S461	S461C	461	Missense	central	0	yes	12.705	0.000	PhosphoSitePlus	TCGA;COSMIC	7.780	Loss
AGC_Akt_AKT1_ST	Q16875	PFKFB3	P31749	AKT1	S461	P464L	464	Missense	distal	3	no	12.705	12.689	PhosphoSitePlus	TCGA;COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	Q16875	PFKFB3	P31749	AKT1	S461	N460Y	460	Missense	proximal	-1	no	12.705	12.697	PhosphoSitePlus	TCGA;COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	Q16875	PFKFB3	P31749	AKT1	T463	S461C	461	Missense	proximal	-2	no	8.557	6.904	EPSD	TCGA;COSMIC	7.780	Loss
AGC_Akt_AKT1_ST	Q16875	PFKFB3	P31749	AKT1	T463	P464L	464	Missense	proximal	1	no	8.557	8.811	EPSD	TCGA;COSMIC	7.780	Up-regulation
AGC_Akt_AKT1_ST	Q16875	PFKFB3	P31749	AKT1	T463	N460Y	460	Missense	distal	-3	no	8.557	8.444	EPSD	TCGA;COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	Q16875	PFKFB3	P31749	AKT1	T463	E469K	469	Missense	distal	6	no	8.557	8.626	EPSD	TCGA;COSMIC	7.780	Up-regulation
AGC_Akt_AKT1_ST	Q16875	PFKFB3	P31749	AKT1	S478	R475G	475	Missense	distal	-3	no	13.716	6.960	EPSD	TCGA;COSMIC	7.780	Loss
AGC_Akt_AKT1_ST	Q15118	PDK1	P31749	AKT1	T346	A349T	349	Missense	distal	3	no	14.110	14.167	PhosphoSitePlus	TCGA;ICGC;COSMIC;GDSC	7.780	Up-regulation
AGC_Akt_AKT1_ST	Q15118	PDK1	P31749	AKT1	T346	E345Q	345	Missense	proximal	-1	no	14.110	14.102	PhosphoSitePlus	TCGA;ICGC;COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	Q15118	PDK1	P31749	AKT1	T346	A353P	353	Missense	distal	7	no	14.110	14.102	PhosphoSitePlus	TCGA;ICGC;COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	Q15118	PDK1	P31749	AKT1	T346	R343H	343	Missense	distal	-3	no	14.110	9.411	PhosphoSitePlus	TCGA;ICGC;COSMIC;GDSC;CCLE	7.780	Down-regulation
AGC_Akt_AKT1_ST	Q15118	PDK1	P31749	AKT1	T431	D429Y	429	Missense	proximal	-2	no	7.501	7.973	EPSD	TCGA;ICGC;COSMIC	7.780	Gain
AGC_Akt_AKT1_ST	P29317	EPHA2	P31749	AKT1	S433	Q436H	436	Missense	distal	3	no	10.266	10.239	EPSD	TCGA;ICGC;COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	P29317	EPHA2	P31749	AKT1	S897	S899G	899	Missense	proximal	2	no	10.610	10.278	PhosphoSitePlus	TCGA;ICGC;COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	P29317	EPHA2	P31749	AKT1	S899	S899G	899	Missense	central	0	yes	9.398	0.000	EPSD	TCGA;ICGC;COSMIC	7.780	Loss
AGC_Akt_AKT1_ST	P29317	EPHA2	P31749	AKT1	S910	R907S	907	Missense	distal	-3	no	11.195	3.419	EPSD	TCGA;ICGC;COSMIC	7.780	Loss
AGC_Akt_AKT1_ST	O15519	CFLAR	P31749	AKT1	S273	R268Q	268	Missense	distal	-5	no	8.098	3.871	PhosphoSitePlus	TCGA;ICGC;COSMIC	7.780	Loss
AGC_Akt_AKT1_ST	O15519	CFLAR	P31749	AKT1	S273	K280N	280	Missense	distal	7	no	8.098	8.063	PhosphoSitePlus	TCGA	7.780	Down-regulation
AGC_Akt_AKT1_ST	P26358	DNMT1	P31749	AKT1	T12	R9L	9	Missense	distal	-3	no	11.540	4.546	EPSD	TCGA;ICGC;COSMIC	7.780	Loss
AGC_Akt_AKT1_ST	P26358	DNMT1	P31749	AKT1	S74	L79P	79	Missense	distal	5	no	11.321	11.334	EPSD	TCGA;ICGC;COSMIC	7.780	Up-regulation
AGC_Akt_AKT1_ST	P26358	DNMT1	P31749	AKT1	S74	S74F	74	Missense	central	0	yes	11.321	0.000	EPSD	TCGA;ICGC;COSMIC	7.780	Loss
AGC_Akt_AKT1_ST	P26358	DNMT1	P31749	AKT1	S977	R974H	974	Missense	distal	-3	no	13.136	8.437	EPSD	TCGA;ICGC;COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	P26358	DNMT1	P31749	AKT1	S1605	I1608M	1608	Missense	distal	3	no	9.912	9.958	EPSD	TCGA;ICGC;COSMIC	7.780	Up-regulation
AGC_Akt_AKT1_ST	Q96KG9	SCYL1	P31749	AKT1	S41	V43L	43	Missense	proximal	2	no	8.542	8.534	EPSD	TCGA;ICGC;COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	Q96KG9	SCYL1	P31749	AKT1	T469	H465D	465	Missense	distal	-4	no	13.647	13.332	PhosphoSitePlus	TCGA;ICGC;COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	Q96KG9	SCYL1	P31749	AKT1	S723	A722T	722	Missense	proximal	-1	no	12.444	12.470	EPSD	TCGA;COSMIC	7.780	Up-regulation
AGC_Akt_AKT1_ST	Q96KG9	SCYL1	P31749	AKT1	T748	R745H	745	Missense	distal	-3	no	9.472	4.774	EPSD	TCGA;ICGC;COSMIC	7.780	Loss
AGC_Akt_AKT1_ST	Q96KG9	SCYL1	P31749	AKT1	T748	S754Y	754	Missense	distal	6	no	9.472	9.384	EPSD	TCGA;ICGC;COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	Q96KG9	SCYL1	P31749	AKT1	S754	S754Y	754	Missense	central	0	yes	10.427	0.000	EPSD	TCGA;ICGC;COSMIC	7.780	Loss
AGC_Akt_AKT1_ST	P15976	GATA1	P31749	AKT1	S116	S116C	116	Missense	central	0	yes	12.092	0.000	EPSD	TCGA;ICGC;COSMIC	7.780	Loss
AGC_Akt_AKT1_ST	P15976	GATA1	P31749	AKT1	S116	E114K	114	Missense	proximal	-2	no	12.092	12.751	EPSD	TCGA;ICGC;COSMIC	7.780	Up-regulation
AGC_Akt_AKT1_ST	P15976	GATA1	P31749	AKT1	S116	A120T	120	Missense	distal	4	no	12.092	11.963	EPSD	TCGA;ICGC;COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	P15976	GATA1	P31749	AKT1	S116	V121M	121	Missense	distal	5	no	12.092	12.095	EPSD	TCGA;ICGC;COSMIC	7.780	Up-regulation
AGC_Akt_AKT1_ST	P15976	GATA1	P31749	AKT1	S116	T112N	112	Missense	distal	-4	no	12.092	11.469	EPSD	TCGA;ICGC;COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	P15976	GATA1	P31749	AKT1	S116	A120V	120	Missense	distal	4	no	12.092	12.148	EPSD	TCGA;ICGC;COSMIC;CCLE	7.780	Up-regulation
AGC_Akt_AKT1_ST	P15976	GATA1	P31749	AKT1	T256	R253Q	253	Missense	distal	-3	no	10.228	3.017	EPSD	TCGA;ICGC;COSMIC	7.780	Loss
AGC_Akt_AKT1_ST	P15976	GATA1	P31749	AKT1	S310	R307L	307	Missense	distal	-3	no	17.117	10.123	PhosphoSitePlus	TCGA;ICGC;COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	P15976	GATA1	P31749	AKT1	S310	R317G	317	Missense	distal	7	no	17.117	17.036	PhosphoSitePlus	TCGA;ICGC;COSMIC;CCLE	7.780	Down-regulation
AGC_Akt_AKT1_ST	P15976	GATA1	P31749	AKT1	S310	G313W	313	Missense	distal	3	no	17.117	17.079	PhosphoSitePlus	TCGA;ICGC	7.780	Down-regulation
AGC_Akt_AKT1_ST	P15976	GATA1	P31749	AKT1	S310	R307H	307	Missense	distal	-3	no	17.117	12.418	PhosphoSitePlus	TCGA;ICGC;CCLE	7.780	Down-regulation
AGC_Akt_AKT1_ST	P15976	GATA1	P31749	AKT1	S319	R317G	317	Missense	proximal	-2	no	10.053	9.547	EPSD	TCGA;ICGC;COSMIC;CCLE	7.780	Down-regulation
AGC_Akt_AKT1_ST	P15976	GATA1	P31749	AKT1	S319	G313W	313	Missense	distal	-6	no	10.053	10.020	EPSD	TCGA;ICGC	7.780	Down-regulation
AGC_Akt_AKT1_ST	P15976	GATA1	P31749	AKT1	S320	R317G	317	Missense	distal	-3	no	13.443	6.687	EPSD	TCGA;ICGC;COSMIC;CCLE	7.780	Loss
AGC_Akt_AKT1_ST	P15976	GATA1	P31749	AKT1	S320	A327S	327	Missense	distal	7	no	13.443	13.494	EPSD	TCGA;ICGC;COSMIC	7.780	Up-regulation
AGC_Akt_AKT1_ST	P15976	GATA1	P31749	AKT1	S320	G313W	313	Missense	distal	-7	no	13.443	13.262	EPSD	TCGA;ICGC	7.780	Down-regulation
AGC_Akt_AKT1_ST	Q99418	CYTH2	P31749	AKT1	T276	G271S	271	Missense	distal	-5	no	11.605	11.199	PhosphoSitePlus	TCGA;ICGC;COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	Q99418	CYTH2	P31749	AKT1	T276	R279H	279	Missense	distal	3	no	11.605	11.521	PhosphoSitePlus	TCGA;COSMIC;CCLE	7.780	Down-regulation
AGC_Akt_AKT1_ST	Q99418	CYTH2	P31749	AKT1	S392	A385V	385	Missense	distal	-7	no	15.149	15.020	EPSD	TCGA;COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	Q99502	EYA1	P31749	AKT1	S17	E18K	18	Missense	proximal	1	no	7.681	7.845	EPSD	TCGA;ICGC;COSMIC	7.780	Gain
AGC_Akt_AKT1_ST	Q99502	EYA1	P31749	AKT1	S17	H10N	10	Missense	distal	-7	no	7.681	7.812	EPSD	TCGA;ICGC;COSMIC	7.780	Gain
AGC_Akt_AKT1_ST	Q99502	EYA1	P31749	AKT1	S299	D300H	300	Missense	proximal	1	no	16.579	16.614	PhosphoSitePlus	TCGA;COSMIC	7.780	Up-regulation
AGC_Akt_AKT1_ST	Q99502	EYA1	P31749	AKT1	S299	S299L	299	Missense	central	0	yes	16.579	0.000	PhosphoSitePlus	TCGA;COSMIC	7.780	Loss
AGC_Akt_AKT1_ST	Q99502	EYA1	P31749	AKT1	S299	R294G	294	Missense	distal	-5	no	16.579	12.514	PhosphoSitePlus	TCGA;COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	Q99502	EYA1	P31749	AKT1	S299	K302Q	302	Missense	distal	3	no	16.579	16.504	PhosphoSitePlus	TCGA;COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	Q99502	EYA1	P31749	AKT1	S299	R296H	296	Missense	distal	-3	no	16.579	11.880	PhosphoSitePlus	TCGA;COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	Q99502	EYA1	P31749	AKT1	S299	G301W	301	Missense	proximal	2	no	16.579	16.284	PhosphoSitePlus	TCGA;COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	Q99502	EYA1	P31749	AKT1	S299	S292Y	292	Missense	distal	-7	no	16.579	16.373	PhosphoSitePlus	TCGA	7.780	Down-regulation
AGC_Akt_AKT1_ST	Q99502	EYA1	P31749	AKT1	S299	L295W	295	Missense	distal	-4	no	16.579	16.239	PhosphoSitePlus	TCGA;COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	Q99502	EYA1	P31749	AKT1	S299	R296C	296	Missense	distal	-3	no	16.579	10.405	PhosphoSitePlus	TCGA;COSMIC;GDSC;CCLE	7.780	Down-regulation
AGC_Akt_AKT1_ST	Q99502	EYA1	P31749	AKT1	S299	R304C	304	Missense	distal	5	no	16.579	16.453	PhosphoSitePlus	TCGA;COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	Q99502	EYA1	P31749	AKT1	S314	R309G	309	Missense	distal	-5	no	7.980	3.916	EPSD	TCGA;COSMIC	7.780	Loss
AGC_Akt_AKT1_ST	Q99502	EYA1	P31749	AKT1	S314	N312K	312	Missense	proximal	-2	no	7.980	8.917	EPSD	TCGA;ICGC;COSMIC	7.780	Up-regulation
AGC_Akt_AKT1_ST	Q99502	EYA1	P31749	AKT1	S314	R308Q	308	Missense	distal	-6	no	7.980	7.896	EPSD	TCGA;COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	Q99502	EYA1	P31749	AKT1	S314	P316S	316	Missense	proximal	2	no	7.980	8.317	EPSD	TCGA;COSMIC	7.780	Up-regulation
AGC_Akt_AKT1_ST	Q99502	EYA1	P31749	AKT1	S314	P313L	313	Missense	proximal	-1	no	7.980	7.981	EPSD	TCGA;COSMIC	7.780	Up-regulation
AGC_Akt_AKT1_ST	Q99502	EYA1	P31749	AKT1	S314	P317S	317	Missense	distal	3	no	7.980	8.062	EPSD	TCGA;COSMIC	7.780	Up-regulation
AGC_Akt_AKT1_ST	Q99502	EYA1	P31749	AKT1	S314	D318E	318	Missense	distal	4	no	7.980	7.834	EPSD	TCGA;COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	Q99502	EYA1	P31749	AKT1	S314	N312S	312	Missense	proximal	-2	no	7.980	8.666	EPSD	TCGA	7.780	Up-regulation
AGC_Akt_AKT1_ST	Q99502	EYA1	P31749	AKT1	S314	S319Y	319	Missense	distal	5	no	7.980	7.937	EPSD	TCGA;COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	P17542	TAL1	P31749	AKT1	S7	R11S	11	Missense	distal	4	no	12.747	12.736	EPSD	TCGA;ICGC;COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	P17542	TAL1	P31749	AKT1	S7	A9V	9	Missense	proximal	2	no	12.747	12.585	EPSD	TCGA;ICGC;COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	P17542	TAL1	P31749	AKT1	S172	P171L	171	Missense	proximal	-1	no	11.400	11.401	EPSD	TCGA;COSMIC;GDSC;CCLE	7.780	Up-regulation
AGC_Akt_AKT1_ST	P17542	TAL1	P31749	AKT1	T216	P219Q	219	Missense	distal	3	no	8.004	8.013	EPSD	TCGA;ICGC;COSMIC	7.780	Up-regulation
AGC_Akt_AKT1_ST	P17542	TAL1	P31749	AKT1	T216	P218S	218	Missense	proximal	2	no	8.004	8.340	EPSD	TCGA;ICGC;COSMIC	7.780	Up-regulation
AGC_Akt_AKT1_ST	P17542	TAL1	P31749	AKT1	S224	P219Q	219	Missense	distal	-5	no	8.208	7.991	EPSD	TCGA;ICGC;COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	P17542	TAL1	P31749	AKT1	S224	P218S	218	Missense	distal	-6	no	8.208	8.272	EPSD	TCGA;ICGC;COSMIC	7.780	Up-regulation
AGC_Akt_AKT1_ST	P17542	TAL1	P31749	AKT1	T256	T256N	256	Missense	central	0	yes	11.600	0.000	EPSD	TCGA;ICGC	7.780	Loss
AGC_Akt_AKT1_ST	P17542	TAL1	P31749	AKT1	T256	K258N	258	Missense	proximal	2	no	11.600	11.315	EPSD	TCGA;ICGC;COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	P17542	TAL1	P31749	AKT1	T256	R253Q	253	Missense	distal	-3	no	11.600	4.388	EPSD	TCGA;ICGC;COSMIC	7.780	Loss
AGC_Akt_AKT1_ST	P17542	TAL1	P31749	AKT1	T256	R253W	253	Missense	distal	-3	no	11.600	2.659	EPSD	TCGA;COSMIC;CCLE	7.780	Loss
AGC_Akt_AKT1_ST	P17542	TAL1	P31749	AKT1	T256	D259N	259	Missense	distal	3	no	11.600	11.655	EPSD	TCGA;COSMIC	7.780	Up-regulation
AGC_Akt_AKT1_ST	P17542	TAL1	P31749	AKT1	S316	A309V	309	Missense	distal	-7	no	8.110	7.982	EPSD	TCGA;COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	P17542	TAL1	P31749	AKT1	S316	T313K	313	Missense	distal	-3	no	8.110	10.611	EPSD	TCGA;COSMIC	7.780	Up-regulation
AGC_Akt_AKT1_ST	P17542	TAL1	P31749	AKT1	S316	A309E	309	Missense	distal	-7	no	8.110	8.109	EPSD	TCGA;COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	P17542	TAL1	P31749	AKT1	S316	P319S	319	Missense	distal	3	no	8.110	8.191	EPSD	TCGA;ICGC;COSMIC;CCLE	7.780	Up-regulation
AGC_Akt_AKT1_ST	Q92934	BAD	P31749	AKT1	S17	E19D	19	Missense	proximal	2	no	8.321	7.911	EPSD	TCGA;ICGC;COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	Q92934	BAD	P31749	AKT1	S25	E19D	19	Missense	distal	-6	no	8.979	8.907	EPSD	TCGA;ICGC;COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	Q92934	BAD	P31749	AKT1	S25	S25N	25	Missense	central	0	yes	8.979	0.000	EPSD	TCGA	7.780	Loss
AGC_Akt_AKT1_ST	Q92934	BAD	P31749	AKT1	S75	S71I	71	Missense	distal	-4	no	15.295	13.914	EPSD	TCGA;ICGC;COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	Q92934	BAD	P31749	AKT1	S97	A100T	100	Missense	distal	3	no	10.874	10.931	EPSD	TCGA;ICGC;COSMIC	7.780	Up-regulation
AGC_Akt_AKT1_ST	Q92934	BAD	P31749	AKT1	S99	A100T	100	Missense	proximal	1	no	15.195	15.462	PhosphoSitePlus	TCGA;ICGC;COSMIC	7.780	Up-regulation
AGC_Akt_AKT1_ST	Q92934	BAD	P31749	AKT1	S118	M117I	117	Missense	proximal	-1	no	10.696	10.676	EPSD	TCGA;ICGC;COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	Q92934	BAD	P31749	AKT1	S134	R131H	131	Missense	distal	-3	no	11.762	7.064	EPSD	TCGA;ICGC;COSMIC	7.780	Loss
AGC_Akt_AKT1_ST	Q92934	BAD	P31749	AKT1	S134	G136D	136	Missense	proximal	2	no	11.762	11.495	EPSD	TCGA;ICGC;COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	Q92934	BAD	P31749	AKT1	S134	S134I	134	Missense	central	0	yes	11.762	0.000	EPSD	TCGA	7.780	Loss
AGC_Akt_AKT1_ST	Q92934	BAD	P31749	AKT1	S164	G162V	162	Missense	proximal	-2	no	13.174	12.679	EPSD	TCGA;ICGC;COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	Q92934	BAD	P31749	AKT1	S164	S164F	164	Missense	central	0	yes	13.174	0.000	EPSD	TCGA;ICGC;COSMIC;GDSC;CCLE	7.780	Loss
AGC_Akt_AKT1_ST	Q92934	BAD	P31749	AKT1	S164	S167P	167	Missense	distal	3	no	13.174	13.093	EPSD	TCGA;COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	Q92934	BAD	P31749	AKT1	S164	S163N	163	Missense	proximal	-1	no	13.174	13.156	EPSD	TCGA;ICGC;COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	Q92934	BAD	P31749	AKT1	S164	G162E	162	Missense	proximal	-2	no	13.174	13.461	EPSD	TCGA;ICGC	7.780	Up-regulation
AGC_Akt_AKT1_ST	P09651	HNRNPA1	P31749	AKT1	S6	E5Q	5	Missense	proximal	-1	no	9.809	9.801	EPSD	TCGA;ICGC;COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	P09651	HNRNPA1	P31749	AKT1	S6	P7R	7	Missense	proximal	1	no	9.809	10.109	EPSD	TCGA;ICGC;COSMIC	7.780	Up-regulation
AGC_Akt_AKT1_ST	P09651	HNRNPA1	P31749	AKT1	S6	P10S	10	Missense	distal	4	no	9.809	9.653	EPSD	TCGA;ICGC;COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	P09651	HNRNPA1	P31749	AKT1	S6	L13P	13	Missense	distal	7	no	9.809	9.817	EPSD	TCGA;ICGC;COSMIC	7.780	Up-regulation
AGC_Akt_AKT1_ST	P09651	HNRNPA1	P31749	AKT1	S91	R97T	97	Missense	distal	6	no	12.353	12.375	EPSD	TCGA;ICGC;COSMIC	7.780	Up-regulation
AGC_Akt_AKT1_ST	P09651	HNRNPA1	P31749	AKT1	S95	R97T	97	Missense	proximal	2	no	13.995	14.092	EPSD	TCGA;ICGC;COSMIC	7.780	Up-regulation
AGC_Akt_AKT1_ST	P09651	HNRNPA1	P31749	AKT1	S182	E185D	185	Missense	distal	3	no	8.643	8.572	EPSD	TCGA;ICGC;COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	P09651	HNRNPA1	P31749	AKT1	S182	E185K	185	Missense	distal	3	no	8.643	8.686	EPSD	TCGA;ICGC;COSMIC	7.780	Up-regulation
AGC_Akt_AKT1_ST	P09651	HNRNPA1	P31749	AKT1	S182	R178K	178	Missense	distal	-4	no	8.643	8.630	EPSD	TCGA;ICGC;COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	P09651	HNRNPA1	P31749	AKT1	S182	A180D	180	Missense	proximal	-2	no	8.643	7.702	EPSD	TCGA;ICGC;COSMIC	7.780	Loss
AGC_Akt_AKT1_ST	P09651	HNRNPA1	P31749	AKT1	S188	E185D	185	Missense	distal	-3	no	7.218	7.839	EPSD	TCGA;ICGC;COSMIC	7.780	Gain
AGC_Akt_AKT1_ST	P09651	HNRNPA1	P31749	AKT1	S188	E185K	185	Missense	distal	-3	no	7.218	9.269	EPSD	TCGA;ICGC;COSMIC	7.780	Gain
AGC_Akt_AKT1_ST	P09651	HNRNPA1	P31749	AKT1	S197	R194T	194	Missense	distal	-3	no	10.758	3.737	EPSD	TCGA;ICGC;COSMIC	7.780	Loss
AGC_Akt_AKT1_ST	P09651	HNRNPA1	P31749	AKT1	S197	G200A	200	Missense	distal	3	no	10.758	10.791	EPSD	TCGA;ICGC;COSMIC	7.780	Up-regulation
AGC_Akt_AKT1_ST	P09651	HNRNPA1	P31749	AKT1	S197	G198C	198	Missense	proximal	1	no	10.758	10.680	EPSD	TCGA;ICGC;COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	P09651	HNRNPA1	P31749	AKT1	S199	R194T	194	Missense	distal	-5	no	17.470	13.741	PhosphoSitePlus	TCGA;ICGC;COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	P09651	HNRNPA1	P31749	AKT1	S199	G200A	200	Missense	proximal	1	no	17.470	17.702	PhosphoSitePlus	TCGA;ICGC;COSMIC	7.780	Up-regulation
AGC_Akt_AKT1_ST	P09651	HNRNPA1	P31749	AKT1	S199	G198C	198	Missense	proximal	-1	no	17.470	17.440	PhosphoSitePlus	TCGA;ICGC;COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	P09651	HNRNPA1	P31749	AKT1	S286	G283R	283	Missense	distal	-3	no	4.361	11.117	EPSD	TCGA;ICGC;COSMIC	7.780	Gain
AGC_Akt_AKT1_ST	P09651	HNRNPA1	P31749	AKT1	S361	G359S	359	Missense	proximal	-2	no	8.142	8.837	EPSD	TCGA;COSMIC	7.780	Up-regulation
AGC_Akt_AKT1_ST	P09651	HNRNPA1	P31749	AKT1	S361	S365T	365	Missense	distal	4	no	8.142	8.137	EPSD	TCGA;COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	P09651	HNRNPA1	P31749	AKT1	S362	G359S	359	Missense	distal	-3	no	8.009	6.988	EPSD	TCGA;COSMIC	7.780	Loss
AGC_Akt_AKT1_ST	P09651	HNRNPA1	P31749	AKT1	S362	S365T	365	Missense	distal	3	no	8.009	8.008	EPSD	TCGA;COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	P09651	HNRNPA1	P31749	AKT1	S363	G359S	359	Missense	distal	-4	no	7.745	8.474	EPSD	TCGA;COSMIC	7.780	Gain
AGC_Akt_AKT1_ST	P84022	SMAD3	P31749	AKT1	T132	L135V	135	Missense	distal	3	no	9.972	9.979	EPSD	TCGA;ICGC;COSMIC	7.780	Up-regulation
AGC_Akt_AKT1_ST	P84022	SMAD3	P31749	AKT1	T132	Q128H	128	Missense	distal	-4	no	9.972	9.534	EPSD	TCGA;ICGC;COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	P84022	SMAD3	P31749	AKT1	T388	A382V	382	Missense	distal	-6	no	10.153	10.133	EPSD	TCGA;ICGC;COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	P84022	SMAD3	P31749	AKT1	T388	C394F	394	Missense	distal	6	no	10.153	10.236	EPSD	TCGA;ICGC;COSMIC	7.780	Up-regulation
AGC_Akt_AKT1_ST	P84022	SMAD3	P31749	AKT1	T388	P393L	393	Missense	distal	5	no	10.153	10.140	EPSD	TCGA;ICGC;COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	P84022	SMAD3	P31749	AKT1	T412	S416F	416	Missense	distal	4	no	7.628	7.824	EPSD	TCGA;ICGC;COSMIC	7.780	Gain
AGC_Akt_AKT1_ST	P84022	SMAD3	P31749	AKT1	S423	S416F	416	Missense	distal	-7	no	12.093	11.815	EPSD	TCGA;ICGC;COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	P84022	SMAD3	P31749	AKT1	S423	S418I	418	Missense	distal	-5	no	12.093	11.996	EPSD	TCGA;COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	P84022	SMAD3	P31749	AKT1	S423	R420H	420	Missense	distal	-3	no	12.093	7.394	EPSD	TCGA;ICGC;COSMIC	7.780	Loss
AGC_Akt_AKT1_ST	P84022	SMAD3	P31749	AKT1	S423	S423R	423	Missense	central	0	yes	12.093	0.000	EPSD	TCGA;ICGC;COSMIC	7.780	Loss
AGC_Akt_AKT1_ST	P84022	SMAD3	P31749	AKT1	S423	P417L	417	Missense	distal	-6	no	12.093	12.106	EPSD	TCGA;ICGC;COSMIC	7.780	Up-regulation
AGC_Akt_AKT1_ST	P84022	SMAD3	P31749	AKT1	S423	S418N	418	Missense	distal	-5	no	12.093	12.079	EPSD	TCGA;ICGC;COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	P84022	SMAD3	P31749	AKT1	S425	S418I	418	Missense	distal	-7	no	9.123	8.751	EPSD	TCGA;COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	P84022	SMAD3	P31749	AKT1	S425	R420H	420	Missense	distal	-5	no	9.123	6.028	EPSD	TCGA;ICGC;COSMIC	7.780	Loss
AGC_Akt_AKT1_ST	P84022	SMAD3	P31749	AKT1	S425	S423R	423	Missense	proximal	-2	no	9.123	8.935	EPSD	TCGA;ICGC;COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	P84022	SMAD3	P31749	AKT1	S425	S418N	418	Missense	distal	-7	no	9.123	9.009	EPSD	TCGA;ICGC;COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	P18031	PTPN1	P31749	AKT1	S50	D53H	53	Missense	distal	3	no	15.185	15.197	PhosphoSitePlus	TCGA;COSMIC	7.780	Up-regulation
AGC_Akt_AKT1_ST	P18031	PTPN1	P31749	AKT1	S50	Y46H	46	Missense	distal	-4	no	15.185	15.072	PhosphoSitePlus	TCGA;ICGC;COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	P18031	PTPN1	P31749	AKT1	S50	D48Y	48	Missense	proximal	-2	no	15.185	15.657	PhosphoSitePlus	TCGA;ICGC;COSMIC	7.780	Up-regulation
AGC_Akt_AKT1_ST	P18031	PTPN1	P31749	AKT1	S50	P51L	51	Missense	proximal	1	no	15.185	15.439	PhosphoSitePlus	TCGA;ICGC	7.780	Up-regulation
AGC_Akt_AKT1_ST	P18031	PTPN1	P31749	AKT1	S50	R43Q	43	Missense	distal	-7	no	15.185	14.991	PhosphoSitePlus	TCGA;ICGC	7.780	Down-regulation
AGC_Akt_AKT1_ST	P18031	PTPN1	P31749	AKT1	T224	R221K	221	Missense	distal	-3	no	9.882	5.362	EPSD	TCGA	7.780	Loss
AGC_Akt_AKT1_ST	P18031	PTPN1	P31749	AKT1	T224	A217T	217	Missense	distal	-7	no	9.882	10.082	EPSD	TCGA;COSMIC	7.780	Up-regulation
AGC_Akt_AKT1_ST	P18031	PTPN1	P31749	AKT1	T224	D229N	229	Missense	distal	5	no	9.882	9.923	EPSD	TCGA;COSMIC	7.780	Up-regulation
AGC_Akt_AKT1_ST	P18031	PTPN1	P31749	AKT1	T224	C231G	231	Missense	distal	7	no	9.882	9.931	EPSD	TCGA;COSMIC	7.780	Up-regulation
AGC_Akt_AKT1_ST	P18031	PTPN1	P31749	AKT1	T224	G220D	220	Missense	distal	-4	no	9.882	9.324	EPSD	TCGA;COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	P18031	PTPN1	P31749	AKT1	T224	G220S	220	Missense	distal	-4	no	9.882	10.611	EPSD	TCGA	7.780	Up-regulation
AGC_Akt_AKT1_ST	P18031	PTPN1	P31749	AKT1	T224	I219T	219	Missense	distal	-5	no	9.882	10.720	EPSD	TCGA;COSMIC	7.780	Up-regulation
AGC_Akt_AKT1_ST	P18031	PTPN1	P31749	AKT1	S243	V244I	244	Missense	proximal	1	no	9.744	9.496	EPSD	TCGA;COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	P18031	PTPN1	P31749	AKT1	S378	V375L	375	Missense	distal	-3	no	8.454	8.325	EPSD	TCGA;COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	P68400	CSNK2A1	P31749	AKT1	T13	A9D	9	Missense	distal	-4	no	15.151	14.585	PhosphoSitePlus	TCGA;ICGC;COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	P68400	CSNK2A1	P31749	AKT1	S194	E201K	201	Missense	distal	7	no	10.046	10.080	EPSD	TCGA;ICGC;COSMIC	7.780	Up-regulation
AGC_Akt_AKT1_ST	P68400	CSNK2A1	P31749	AKT1	S194	R191Q	191	Missense	distal	-3	no	10.046	2.835	EPSD	TCGA;ICGC;COSMIC	7.780	Loss
AGC_Akt_AKT1_ST	P68400	CSNK2A1	P31749	AKT1	S194	R195Q	195	Missense	proximal	1	no	10.046	9.751	EPSD	TCGA;ICGC;COSMIC;CCLE	7.780	Down-regulation
AGC_Akt_AKT1_ST	P68400	CSNK2A1	P31749	AKT1	S194	F197L	197	Missense	distal	3	no	10.046	10.047	EPSD	TCGA;ICGC;COSMIC;CCLE	7.780	Up-regulation
AGC_Akt_AKT1_ST	P68400	CSNK2A1	P31749	AKT1	S194	P200L	200	Missense	distal	6	no	10.046	10.036	EPSD	TCGA;ICGC;COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	P68400	CSNK2A1	P31749	AKT1	S336	D330V	330	Missense	distal	-6	no	11.358	11.401	EPSD	TCGA;ICGC;COSMIC	7.780	Up-regulation
AGC_Akt_AKT1_ST	P68400	CSNK2A1	P31749	AKT1	S336	G341W	341	Missense	distal	5	no	11.358	11.334	EPSD	TCGA;ICGC;COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	P68400	CSNK2A1	P31749	AKT1	S338	G341W	341	Missense	distal	3	no	9.548	9.510	EPSD	TCGA;ICGC;COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	Q96HP0	DOCK6	P31749	AKT1	S176	R174C	174	Missense	proximal	-2	no	13.373	11.909	EPSD	TCGA;ICGC;COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	Q96HP0	DOCK6	P31749	AKT1	S178	R174C	174	Missense	distal	-4	no	9.978	8.299	EPSD	TCGA;ICGC;COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	Q96HP0	DOCK6	P31749	AKT1	S189	D193N	193	Missense	distal	4	no	8.651	8.536	EPSD	TCGA;ICGC;COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	Q96HP0	DOCK6	P31749	AKT1	S189	I191T	191	Missense	proximal	2	no	8.651	9.233	EPSD	TCGA;ICGC;COSMIC	7.780	Up-regulation
AGC_Akt_AKT1_ST	Q96HP0	DOCK6	P31749	AKT1	S439	F446V	446	Missense	distal	7	no	9.361	9.379	EPSD	TCGA;ICGC;COSMIC	7.780	Up-regulation
AGC_Akt_AKT1_ST	Q96HP0	DOCK6	P31749	AKT1	S484	P491S	491	Missense	distal	7	no	11.184	11.243	EPSD	TCGA;ICGC;COSMIC	7.780	Up-regulation
AGC_Akt_AKT1_ST	Q96HP0	DOCK6	P31749	AKT1	T493	D499N	499	Missense	distal	6	no	14.032	14.114	EPSD	TCGA;ICGC;COSMIC	7.780	Up-regulation
AGC_Akt_AKT1_ST	Q96HP0	DOCK6	P31749	AKT1	T493	V492E	492	Missense	proximal	-1	no	14.032	14.052	EPSD	TCGA;ICGC;COSMIC	7.780	Up-regulation
AGC_Akt_AKT1_ST	Q96HP0	DOCK6	P31749	AKT1	T493	P491S	491	Missense	proximal	-2	no	14.032	14.856	EPSD	TCGA;ICGC;COSMIC	7.780	Up-regulation
AGC_Akt_AKT1_ST	Q96HP0	DOCK6	P31749	AKT1	S872	K879N	879	Missense	distal	7	no	11.378	11.342	EPSD	TCGA;ICGC;COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	Q96HP0	DOCK6	P31749	AKT1	S872	A871T	871	Missense	proximal	-1	no	11.378	11.404	EPSD	TCGA;ICGC;COSMIC	7.780	Up-regulation
AGC_Akt_AKT1_ST	Q96HP0	DOCK6	P31749	AKT1	S872	R877H	877	Missense	distal	5	no	11.378	11.304	EPSD	TCGA;ICGC;COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	Q96HP0	DOCK6	P31749	AKT1	S872	R865C	865	Missense	distal	-7	no	11.378	10.899	EPSD	TCGA;ICGC;COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	Q96HP0	DOCK6	P31749	AKT1	S872	R869C	869	Missense	distal	-3	no	11.378	5.204	EPSD	TCGA;ICGC;COSMIC	7.780	Loss
AGC_Akt_AKT1_ST	Q96HP0	DOCK6	P31749	AKT1	S872	R869H	869	Missense	distal	-3	no	11.378	6.679	EPSD	TCGA;ICGC	7.780	Loss
AGC_Akt_AKT1_ST	Q96HP0	DOCK6	P31749	AKT1	S872	A876V	876	Missense	distal	4	no	11.378	11.433	EPSD	TCGA;ICGC;COSMIC	7.780	Up-regulation
AGC_Akt_AKT1_ST	Q96HP0	DOCK6	P31749	AKT1	S880	K879N	879	Missense	proximal	-1	no	12.286	12.261	EPSD	TCGA;ICGC;COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	Q96HP0	DOCK6	P31749	AKT1	S880	R877H	877	Missense	distal	-3	no	12.286	7.587	EPSD	TCGA;ICGC;COSMIC	7.780	Loss
AGC_Akt_AKT1_ST	Q96HP0	DOCK6	P31749	AKT1	S880	A876V	876	Missense	distal	-4	no	12.286	11.914	EPSD	TCGA;ICGC;COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	Q96HP0	DOCK6	P31749	AKT1	S882	K879N	879	Missense	distal	-3	no	11.961	9.005	EPSD	TCGA;ICGC;COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	Q96HP0	DOCK6	P31749	AKT1	S882	R877H	877	Missense	distal	-5	no	11.961	8.866	EPSD	TCGA;ICGC;COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	Q96HP0	DOCK6	P31749	AKT1	S882	A876V	876	Missense	distal	-6	no	11.961	11.941	EPSD	TCGA;ICGC;COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	Q96HP0	DOCK6	P31749	AKT1	S1073	S1069L	1069	Missense	distal	-4	no	8.260	7.136	EPSD	TCGA;ICGC;COSMIC;CCLE	7.780	Loss
AGC_Akt_AKT1_ST	Q96HP0	DOCK6	P31749	AKT1	S1194	M1195I	1195	Missense	proximal	1	no	15.967	15.781	PhosphoSitePlus	TCGA;ICGC;COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	Q96HP0	DOCK6	P31749	AKT1	S1343	P1348T	1348	Missense	distal	5	no	14.730	14.783	EPSD	TCGA	7.780	Up-regulation
AGC_Akt_AKT1_ST	Q96HP0	DOCK6	P31749	AKT1	S1343	R1340H	1340	Missense	distal	-3	no	14.730	10.031	EPSD	TCGA;COSMIC;GDSC;CCLE	7.780	Down-regulation
AGC_Akt_AKT1_ST	Q96HP0	DOCK6	P31749	AKT1	S1343	F1345V	1345	Missense	proximal	2	no	14.730	14.769	EPSD	TCGA;ICGC	7.780	Up-regulation
AGC_Akt_AKT1_ST	Q96HP0	DOCK6	P31749	AKT1	S1343	F1345S	1345	Missense	proximal	2	no	14.730	15.307	EPSD	TCGA;ICGC	7.780	Up-regulation
AGC_Akt_AKT1_ST	P62424	RPL7A	P31749	AKT1	T106	E105G	105	Missense	proximal	-1	no	12.130	12.115	PhosphoSitePlus	TCGA;ICGC;COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	P62424	RPL7A	P31749	AKT1	T106	K107N	107	Missense	proximal	1	no	12.130	11.974	PhosphoSitePlus	TCGA;ICGC;COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	P22736	NR4A1	P31749	AKT1	S23	P28L	28	Missense	distal	5	no	9.619	9.605	EPSD	TCGA;COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	P42858	HTT	P31749	AKT1	S463	E456K	456	Missense	distal	-7	no	9.890	10.083	EPSD	TCGA;ICGC;COSMIC	7.780	Up-regulation
AGC_Akt_AKT1_ST	P42858	HTT	P31749	AKT1	S463	S462N	462	Missense	proximal	-1	no	9.890	9.872	EPSD	TCGA;ICGC;COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	P42858	HTT	P31749	AKT1	S640	D645Y	645	Missense	distal	5	no	12.805	12.837	EPSD	TCGA;ICGC;COSMIC	7.780	Up-regulation
AGC_Akt_AKT1_ST	P42858	HTT	P31749	AKT1	S642	D645Y	645	Missense	distal	3	no	10.193	10.236	EPSD	TCGA;ICGC;COSMIC	7.780	Up-regulation
AGC_Akt_AKT1_ST	P42858	HTT	P31749	AKT1	S689	R686H	686	Missense	distal	-3	no	11.547	6.848	EPSD	TCGA;ICGC	7.780	Loss
AGC_Akt_AKT1_ST	P42858	HTT	P31749	AKT1	S689	G696R	696	Missense	distal	7	no	11.547	11.627	EPSD	TCGA	7.780	Up-regulation
AGC_Akt_AKT1_ST	P42858	HTT	P31749	AKT1	S689	S691L	691	Missense	proximal	2	no	11.547	11.001	EPSD	TCGA;ICGC;COSMIC;CCLE	7.780	Down-regulation
AGC_Akt_AKT1_ST	P42858	HTT	P31749	AKT1	S689	R686C	686	Missense	distal	-3	no	11.547	5.373	EPSD	TCGA;ICGC;COSMIC	7.780	Loss
AGC_Akt_AKT1_ST	P42858	HTT	P31749	AKT1	S1111	E1114K	1114	Missense	distal	3	no	9.187	9.230	EPSD	TCGA;ICGC;COSMIC	7.780	Up-regulation
AGC_Akt_AKT1_ST	P42858	HTT	P31749	AKT1	S1111	S1108L	1108	Missense	distal	-3	no	9.187	9.970	EPSD	TCGA;ICGC;COSMIC	7.780	Up-regulation
AGC_Akt_AKT1_ST	P42858	HTT	P31749	AKT1	S1111	S1104Y	1104	Missense	distal	-7	no	9.187	8.981	EPSD	TCGA;ICGC;COSMIC;GDSC;CCLE	7.780	Down-regulation
AGC_Akt_AKT1_ST	P42858	HTT	P31749	AKT1	T1173	P1170R	1170	Missense	distal	-3	no	4.790	11.429	EPSD	TCGA;ICGC;COSMIC	7.780	Gain
AGC_Akt_AKT1_ST	P42858	HTT	P31749	AKT1	S1349	P1352L	1352	Missense	distal	3	no	8.613	8.597	EPSD	TCGA;ICGC;COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	P42858	HTT	P31749	AKT1	S1349	S1347F	1347	Missense	proximal	-2	no	8.613	7.746	EPSD	TCGA;ICGC;COSMIC	7.780	Loss
AGC_Akt_AKT1_ST	P42858	HTT	P31749	AKT1	S1349	R1344C	1344	Missense	distal	-5	no	8.613	4.536	EPSD	TCGA;ICGC;COSMIC	7.780	Loss
AGC_Akt_AKT1_ST	P42858	HTT	P31749	AKT1	S2065	L2064V	2064	Missense	proximal	-1	no	8.055	8.048	EPSD	TCGA;ICGC;COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	P42858	HTT	P31749	AKT1	S2065	R2063C	2063	Missense	proximal	-2	no	8.055	6.591	EPSD	TCGA;ICGC;COSMIC	7.780	Loss
AGC_Akt_AKT1_ST	P42858	HTT	P31749	AKT1	S2065	R2063L	2063	Missense	proximal	-2	no	8.055	7.386	EPSD	TCGA;ICGC;COSMIC	7.780	Loss
AGC_Akt_AKT1_ST	P42858	HTT	P31749	AKT1	S2065	D2060N	2060	Missense	distal	-5	no	8.055	7.616	EPSD	TCGA;ICGC;COSMIC	7.780	Loss
AGC_Akt_AKT1_ST	P42858	HTT	P31749	AKT1	T2066	L2064V	2064	Missense	proximal	-2	no	13.354	13.020	EPSD	TCGA;ICGC;COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	P42858	HTT	P31749	AKT1	T2066	R2063C	2063	Missense	distal	-3	no	13.354	7.180	EPSD	TCGA;ICGC;COSMIC	7.780	Loss
AGC_Akt_AKT1_ST	P42858	HTT	P31749	AKT1	T2066	R2063L	2063	Missense	distal	-3	no	13.354	6.360	EPSD	TCGA;ICGC;COSMIC	7.780	Loss
AGC_Akt_AKT1_ST	P42858	HTT	P31749	AKT1	T2066	D2060N	2060	Missense	distal	-6	no	13.354	13.425	EPSD	TCGA;ICGC;COSMIC	7.780	Up-regulation
AGC_Akt_AKT1_ST	P42858	HTT	P31749	AKT1	T2455	T2459A	2459	Missense	distal	4	no	8.834	8.963	EPSD	TCGA;ICGC;COSMIC	7.780	Up-regulation
AGC_Akt_AKT1_ST	P42858	HTT	P31749	AKT1	T2455	R2461C	2461	Missense	distal	6	no	8.834	8.632	EPSD	TCGA;ICGC;COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	P42858	HTT	P31749	AKT1	S2548	R2551T	2551	Missense	distal	3	no	11.391	11.407	EPSD	TCGA;ICGC;COSMIC	7.780	Up-regulation
AGC_Akt_AKT1_ST	P42858	HTT	P31749	AKT1	S2548	F2543C	2543	Missense	distal	-5	no	11.391	10.836	EPSD	TCGA;ICGC;COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	P05787	KRT8	P31749	AKT1	S9	S15F	15	Missense	distal	6	no	8.946	8.826	EPSD	TCGA;ICGC;COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	P05787	KRT8	P31749	AKT1	S13	S15F	15	Missense	proximal	2	no	9.637	9.060	EPSD	TCGA;ICGC;COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	P05787	KRT8	P31749	AKT1	S21	S15F	15	Missense	distal	-6	no	12.497	12.422	EPSD	TCGA;ICGC;COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	P05787	KRT8	P31749	AKT1	S35	S37F	37	Missense	proximal	2	no	12.612	12.035	EPSD	TCGA;ICGC;COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	P05787	KRT8	P31749	AKT1	S37	S37F	37	Missense	central	0	yes	8.163	0.000	EPSD	TCGA;ICGC;COSMIC	7.780	Loss
AGC_Akt_AKT1_ST	P05787	KRT8	P31749	AKT1	S43	S37F	37	Missense	distal	-6	no	11.867	11.792	EPSD	TCGA;ICGC;COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	P40818	USP8	P31749	AKT1	S425	R422T	422	Missense	distal	-3	no	10.780	3.758	EPSD	TCGA;ICGC;COSMIC	7.780	Loss
AGC_Akt_AKT1_ST	P40818	USP8	P31749	AKT1	S427	R422T	422	Missense	distal	-5	no	11.043	7.313	EPSD	TCGA;ICGC;COSMIC	7.780	Loss
AGC_Akt_AKT1_ST	P40818	USP8	P31749	AKT1	T577	D570H	570	Missense	distal	-7	no	9.779	9.906	EPSD	TCGA;ICGC;COSMIC	7.780	Up-regulation
AGC_Akt_AKT1_ST	P40818	USP8	P31749	AKT1	T618	R620K	620	Missense	proximal	2	no	10.098	10.287	EPSD	TCGA;ICGC;COSMIC	7.780	Up-regulation
AGC_Akt_AKT1_ST	P40818	USP8	P31749	AKT1	T618	L614I	614	Missense	distal	-4	no	10.098	9.841	EPSD	TCGA;ICGC;COSMIC;CCLE	7.780	Down-regulation
AGC_Akt_AKT1_ST	P40818	USP8	P31749	AKT1	T618	D625N	625	Missense	distal	7	no	10.098	10.140	EPSD	TCGA;ICGC;COSMIC	7.780	Up-regulation
AGC_Akt_AKT1_ST	P40818	USP8	P31749	AKT1	T623	R620K	620	Missense	distal	-3	no	10.471	5.951	EPSD	TCGA;ICGC;COSMIC	7.780	Loss
AGC_Akt_AKT1_ST	P40818	USP8	P31749	AKT1	T623	D625N	625	Missense	proximal	2	no	10.471	10.801	EPSD	TCGA;ICGC;COSMIC	7.780	Up-regulation
AGC_Akt_AKT1_ST	P40818	USP8	P31749	AKT1	S641	E643K	643	Missense	proximal	2	no	11.629	11.834	EPSD	TCGA;ICGC;COSMIC	7.780	Up-regulation
AGC_Akt_AKT1_ST	P40818	USP8	P31749	AKT1	S641	R638T	638	Missense	distal	-3	no	11.629	4.608	EPSD	TCGA;ICGC;COSMIC	7.780	Loss
AGC_Akt_AKT1_ST	P40818	USP8	P31749	AKT1	S641	R638K	638	Missense	distal	-3	no	11.629	7.109	EPSD	TCGA;ICGC;COSMIC	7.780	Loss
AGC_Akt_AKT1_ST	P40818	USP8	P31749	AKT1	S641	R638G	638	Missense	distal	-3	no	11.629	4.873	EPSD	TCGA;ICGC;COSMIC	7.780	Loss
AGC_Akt_AKT1_ST	P40818	USP8	P31749	AKT1	S641	R640Q	640	Missense	proximal	-1	no	11.629	11.597	EPSD	TCGA;ICGC;COSMIC;GDSC;CCLE	7.780	Down-regulation
AGC_Akt_AKT1_ST	P40818	USP8	P31749	AKT1	S711	R708G	708	Missense	distal	-3	no	14.396	7.640	EPSD	TCGA;ICGC;COSMIC	7.780	Loss
AGC_Akt_AKT1_ST	P40818	USP8	P31749	AKT1	S711	S716F	716	Missense	distal	5	no	14.396	14.323	EPSD	TCGA;ICGC;COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	P40818	USP8	P31749	AKT1	S711	R715C	715	Missense	distal	4	no	14.396	14.730	EPSD	TCGA;ICGC;COSMIC	7.780	Up-regulation
AGC_Akt_AKT1_ST	P40818	USP8	P31749	AKT1	S718	P720Q	720	Missense	proximal	2	no	11.474	11.521	PhosphoSitePlus	TCGA;ICGC;COSMIC;GDSC	7.780	Up-regulation
AGC_Akt_AKT1_ST	P40818	USP8	P31749	AKT1	S718	P720A	720	Missense	proximal	2	no	11.474	11.434	PhosphoSitePlus	TCGA;ICGC;COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	P40818	USP8	P31749	AKT1	S718	S716F	716	Missense	proximal	-2	no	11.474	10.607	PhosphoSitePlus	TCGA;ICGC;COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	P40818	USP8	P31749	AKT1	S718	R715C	715	Missense	distal	-3	no	11.474	5.300	PhosphoSitePlus	TCGA;ICGC;COSMIC	7.780	Loss
AGC_Akt_AKT1_ST	P40818	USP8	P31749	AKT1	S718	P720S	720	Missense	proximal	2	no	11.474	11.810	PhosphoSitePlus	TCGA;ICGC	7.780	Up-regulation
AGC_Akt_AKT1_ST	P40818	USP8	P31749	AKT1	S719	S716F	716	Missense	distal	-3	no	5.753	7.935	EPSD	TCGA;ICGC;COSMIC	7.780	Gain
AGC_Akt_AKT1_ST	P40818	USP8	P31749	AKT1	T735	R742Q	742	Missense	distal	7	no	11.383	11.327	EPSD	TCGA;ICGC;COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	P40818	USP8	P31749	AKT1	T737	R742Q	742	Missense	distal	5	no	9.216	9.165	EPSD	TCGA;ICGC;COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	P40818	USP8	P31749	AKT1	S846	G840E	840	Missense	distal	-6	no	11.203	11.236	EPSD	TCGA;ICGC;COSMIC	7.780	Up-regulation
AGC_Akt_AKT1_ST	P40818	USP8	P31749	AKT1	S846	I852F	852	Missense	distal	6	no	11.203	11.248	EPSD	TCGA;ICGC	7.780	Up-regulation
AGC_Akt_AKT1_ST	P40818	USP8	P31749	AKT1	S972	T978P	978	Missense	distal	6	no	11.301	11.187	EPSD	TCGA;ICGC;COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	Q969H0	FBXW7	P31749	AKT1	S18	R14Q	14	Missense	distal	-4	no	11.004	10.382	EPSD	TCGA;ICGC;COSMIC;GDSC;CCLE	7.780	Down-regulation
AGC_Akt_AKT1_ST	Q969H0	FBXW7	P31749	AKT1	S227	G233C	233	Missense	distal	6	no	15.464	15.366	PhosphoSitePlus	TCGA;ICGC;COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	Q969H0	FBXW7	P31749	AKT1	S372	G368E	368	Missense	distal	-4	no	8.784	9.002	EPSD	TCGA;ICGC;COSMIC	7.780	Up-regulation
AGC_Akt_AKT1_ST	Q969H0	FBXW7	P31749	AKT1	S372	K374Q	374	Missense	proximal	2	no	8.784	8.478	EPSD	TCGA	7.780	Down-regulation
AGC_Akt_AKT1_ST	Q969H0	FBXW7	P31749	AKT1	S372	W365S	365	Missense	distal	-7	no	8.784	9.151	EPSD	TCGA;ICGC;COSMIC	7.780	Up-regulation
AGC_Akt_AKT1_ST	Q969H0	FBXW7	P31749	AKT1	S372	P373S	373	Missense	proximal	1	no	8.784	8.939	EPSD	TCGA;ICGC;COSMIC	7.780	Up-regulation
AGC_Akt_AKT1_ST	Q969H0	FBXW7	P31749	AKT1	T692	R689W	689	Missense	distal	-3	no	12.179	3.239	EPSD	TCGA;ICGC;COSMIC;GDSC;CCLE	7.780	Loss
AGC_Akt_AKT1_ST	Q969H0	FBXW7	P31749	AKT1	T692	R689Q	689	Missense	distal	-3	no	12.179	4.968	EPSD	TCGA;ICGC;COSMIC	7.780	Loss
AGC_Akt_AKT1_ST	Q04912	MST1R	P31749	AKT1	S1056	E1055K	1055	Missense	proximal	-1	no	10.291	10.312	EPSD	TCGA;COSMIC	7.780	Up-regulation
AGC_Akt_AKT1_ST	Q04912	MST1R	P31749	AKT1	S1056	S1056F	1056	Missense	central	0	yes	10.291	0.000	EPSD	TCGA;COSMIC	7.780	Loss
AGC_Akt_AKT1_ST	Q04912	MST1R	P31749	AKT1	S1394	R1391Q	1391	Missense	distal	-3	no	17.552	10.341	PhosphoSitePlus	TCGA;COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	P63000	RAC1	P31749	AKT1	S71	P69S	69	Missense	proximal	-2	no	13.601	14.426	PhosphoSitePlus	TCGA;ICGC;COSMIC	7.780	Up-regulation
AGC_Akt_AKT1_ST	P63000	RAC1	P31749	AKT1	S71	P73L	73	Missense	proximal	2	no	13.601	13.392	PhosphoSitePlus	TCGA;ICGC;COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	P63000	RAC1	P31749	AKT1	S71	R68S	68	Missense	distal	-3	no	13.601	5.825	PhosphoSitePlus	TCGA;ICGC;COSMIC	7.780	Loss
AGC_Akt_AKT1_ST	P63000	RAC1	P31749	AKT1	S71	R68H	68	Missense	distal	-3	no	13.601	8.903	PhosphoSitePlus	TCGA;ICGC;COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	P63000	RAC1	P31749	AKT1	S71	R68C	68	Missense	distal	-3	no	13.601	7.428	PhosphoSitePlus	TCGA;ICGC;COSMIC	7.780	Loss
AGC_Akt_AKT1_ST	P63000	RAC1	P31749	AKT1	S71	S71F	71	Missense	central	0	yes	13.601	0.000	PhosphoSitePlus	TCGA;ICGC;COSMIC	7.780	Loss
AGC_Akt_AKT1_ST	Q15121	PEA15	P31749	AKT1	S104	R101H	101	Missense	distal	-3	no	12.656	7.957	EPSD	TCGA;COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	Q15121	PEA15	P31749	AKT1	S104	D110G	110	Missense	distal	6	no	12.656	12.700	EPSD	TCGA	7.780	Up-regulation
AGC_Akt_AKT1_ST	Q15121	PEA15	P31749	AKT1	S116	E119K	119	Missense	distal	3	no	11.638	11.681	PhosphoSitePlus	TCGA;COSMIC	7.780	Up-regulation
AGC_Akt_AKT1_ST	Q15121	PEA15	P31749	AKT1	S116	D110G	110	Missense	distal	-6	no	11.638	11.677	PhosphoSitePlus	TCGA	7.780	Up-regulation
AGC_Akt_AKT1_ST	Q15121	PEA15	P31749	AKT1	S116	R113W	113	Missense	distal	-3	no	11.638	2.697	PhosphoSitePlus	TCGA;COSMIC	7.780	Loss
AGC_Akt_AKT1_ST	Q15121	PEA15	P31749	AKT1	S116	E119D	119	Missense	distal	3	no	11.638	11.567	PhosphoSitePlus	TCGA	7.780	Down-regulation
AGC_Akt_AKT1_ST	P04792	HSPB1	P31749	AKT1	S9	L10H	10	Missense	proximal	1	no	10.774	10.498	EPSD	TCGA;ICGC;COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	P04792	HSPB1	P31749	AKT1	S15	L10H	10	Missense	distal	-5	no	10.969	12.001	EPSD	TCGA;ICGC;COSMIC	7.780	Up-regulation
AGC_Akt_AKT1_ST	P04792	HSPB1	P31749	AKT1	S78	L81I	81	Missense	distal	3	no	12.081	12.047	EPSD	TCGA;ICGC;COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	P04792	HSPB1	P31749	AKT1	S82	L81I	81	Missense	proximal	-1	no	12.296	12.275	PhosphoSitePlus	TCGA;ICGC;COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	P04792	HSPB1	P31749	AKT1	T139	F138C	138	Missense	proximal	-1	no	8.247	8.222	EPSD	TCGA;ICGC;COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	P04792	HSPB1	P31749	AKT1	T143	F138C	138	Missense	distal	-5	no	13.469	12.914	EPSD	TCGA;ICGC;COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	P53804	TTC3	P31749	AKT1	S1581	V1580G	1580	Missense	proximal	-1	no	8.211	8.216	EPSD	TCGA;ICGC;COSMIC	7.780	Up-regulation
AGC_Akt_AKT1_ST	P53804	TTC3	P31749	AKT1	S1581	M1586I	1586	Missense	distal	5	no	8.211	8.171	EPSD	TCGA;COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	P53804	TTC3	P31749	AKT1	S1581	V1580L	1580	Missense	proximal	-1	no	8.211	8.217	EPSD	TCGA;ICGC;COSMIC	7.780	Up-regulation
AGC_Akt_AKT1_ST	P53804	TTC3	P31749	AKT1	S1915	Y1912C	1912	Missense	distal	-3	no	9.870	11.286	EPSD	TCGA;ICGC;COSMIC	7.780	Up-regulation
AGC_Akt_AKT1_ST	P56270	MAZ	P31749	AKT1	S222	S222W	222	Missense	central	0	yes	10.247	0.000	EPSD	TCGA;ICGC;COSMIC	7.780	Loss
AGC_Akt_AKT1_ST	P56270	MAZ	P31749	AKT1	S222	G218S	218	Missense	distal	-4	no	10.247	10.976	EPSD	TCGA;COSMIC	7.780	Up-regulation
AGC_Akt_AKT1_ST	P56270	MAZ	P31749	AKT1	S222	T229I	229	Missense	distal	7	no	10.247	10.139	EPSD	TCGA;COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	P56270	MAZ	P31749	AKT1	S300	S302L	302	Missense	proximal	2	no	7.856	7.310	EPSD	TCGA;ICGC;COSMIC	7.780	Loss
AGC_Akt_AKT1_ST	P56270	MAZ	P31749	AKT1	S323	M322I	322	Missense	proximal	-1	no	9.412	9.392	EPSD	TCGA;ICGC;COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	P56270	MAZ	P31749	AKT1	S323	S323N	323	Missense	central	0	yes	9.412	0.000	EPSD	TCGA;COSMIC	7.780	Loss
AGC_Akt_AKT1_ST	P56270	MAZ	P31749	AKT1	T385	E389K	389	Missense	distal	4	no	14.332	14.231	PhosphoSitePlus	TCGA;ICGC;COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	P56270	MAZ	P31749	AKT1	T385	A383V	383	Missense	proximal	-2	no	14.332	13.594	PhosphoSitePlus	TCGA;COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	P56270	MAZ	P31749	AKT1	T385	H384Y	384	Missense	proximal	-1	no	14.332	14.340	PhosphoSitePlus	TCGA;ICGC;COSMIC	7.780	Up-regulation
AGC_Akt_AKT1_ST	P09601	HMOX1	P31749	AKT1	S8	Q11H	11	Missense	distal	3	no	9.807	9.779	EPSD	TCGA;ICGC;COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	P09601	HMOX1	P31749	AKT1	S188	A194T	194	Missense	distal	6	no	16.283	16.386	PhosphoSitePlus	TCGA;ICGC;COSMIC	7.780	Up-regulation
AGC_Akt_AKT1_ST	P09601	HMOX1	P31749	AKT1	S188	R185C	185	Missense	distal	-3	no	16.283	10.109	PhosphoSitePlus	TCGA;ICGC;COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	P09601	HMOX1	P31749	AKT1	S188	R185H	185	Missense	distal	-3	no	16.283	11.584	PhosphoSitePlus	TCGA;ICGC	7.780	Down-regulation
AGC_Akt_AKT1_ST	P09601	HMOX1	P31749	AKT1	S188	E190G	190	Missense	proximal	2	no	16.283	16.140	PhosphoSitePlus	TCGA;ICGC;COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	Q13009	TIAM1	P31749	AKT1	T26	L32I	32	Missense	distal	6	no	11.882	11.821	EPSD	TCGA;ICGC;COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	Q13009	TIAM1	P31749	AKT1	T26	G22E	22	Missense	distal	-4	no	11.882	12.100	EPSD	TCGA;ICGC;COSMIC	7.780	Up-regulation
AGC_Akt_AKT1_ST	Q13009	TIAM1	P31749	AKT1	T26	K24Q	24	Missense	proximal	-2	no	11.882	10.930	EPSD	TCGA;ICGC;COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	Q13009	TIAM1	P31749	AKT1	T26	R28C	28	Missense	proximal	2	no	11.882	11.229	EPSD	TCGA;ICGC;COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	Q13009	TIAM1	P31749	AKT1	T26	R31C	31	Missense	distal	5	no	11.882	11.756	EPSD	TCGA;ICGC;COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	Q13009	TIAM1	P31749	AKT1	T26	H25Y	25	Missense	proximal	-1	no	11.882	11.890	EPSD	TCGA;ICGC;CCLE	7.780	Up-regulation
AGC_Akt_AKT1_ST	Q13009	TIAM1	P31749	AKT1	S33	L32I	32	Missense	proximal	-1	no	9.995	9.974	EPSD	TCGA;ICGC;COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	Q13009	TIAM1	P31749	AKT1	S33	T36M	36	Missense	distal	3	no	9.995	9.911	EPSD	TCGA;ICGC;COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	Q13009	TIAM1	P31749	AKT1	S33	R28C	28	Missense	distal	-5	no	9.995	5.918	EPSD	TCGA;ICGC;COSMIC	7.780	Loss
AGC_Akt_AKT1_ST	Q13009	TIAM1	P31749	AKT1	S33	R31C	31	Missense	proximal	-2	no	9.995	8.531	EPSD	TCGA;ICGC;COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	Q13009	TIAM1	P31749	AKT1	S43	S44L	44	Missense	proximal	1	no	15.019	15.118	EPSD	TCGA;ICGC;COSMIC	7.780	Up-regulation
AGC_Akt_AKT1_ST	Q13009	TIAM1	P31749	AKT1	S43	T36M	36	Missense	distal	-7	no	15.019	14.753	EPSD	TCGA;ICGC;COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	Q13009	TIAM1	P31749	AKT1	S60	R57Q	57	Missense	distal	-3	no	13.091	5.880	EPSD	TCGA;ICGC;COSMIC	7.780	Loss
AGC_Akt_AKT1_ST	Q13009	TIAM1	P31749	AKT1	S102	R99S	99	Missense	distal	-3	no	9.939	2.162	EPSD	TCGA;ICGC;COSMIC	7.780	Loss
AGC_Akt_AKT1_ST	Q13009	TIAM1	P31749	AKT1	S102	R99I	99	Missense	distal	-3	no	9.939	2.858	EPSD	TCGA;ICGC;GDSC;CCLE	7.780	Loss
AGC_Akt_AKT1_ST	Q13009	TIAM1	P31749	AKT1	T104	R99S	99	Missense	distal	-5	no	8.676	4.206	EPSD	TCGA;ICGC;COSMIC	7.780	Loss
AGC_Akt_AKT1_ST	Q13009	TIAM1	P31749	AKT1	T104	R99I	99	Missense	distal	-5	no	8.676	4.109	EPSD	TCGA;ICGC;GDSC;CCLE	7.780	Loss
AGC_Akt_AKT1_ST	Q13009	TIAM1	P31749	AKT1	S170	I175M	175	Missense	distal	5	no	9.616	9.656	EPSD	TCGA;ICGC;COSMIC	7.780	Up-regulation
AGC_Akt_AKT1_ST	Q13009	TIAM1	P31749	AKT1	S170	S164R	164	Missense	distal	-6	no	9.616	9.650	EPSD	TCGA;ICGC;COSMIC	7.780	Up-regulation
AGC_Akt_AKT1_ST	Q13009	TIAM1	P31749	AKT1	S170	R169H	169	Missense	proximal	-1	no	9.616	9.571	EPSD	TCGA;ICGC;COSMIC;CCLE	7.780	Down-regulation
AGC_Akt_AKT1_ST	Q13009	TIAM1	P31749	AKT1	S170	F165V	165	Missense	distal	-5	no	9.616	8.823	EPSD	TCGA;ICGC;COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	Q13009	TIAM1	P31749	AKT1	S170	S164I	164	Missense	distal	-6	no	9.616	9.496	EPSD	TCGA;ICGC;COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	Q13009	TIAM1	P31749	AKT1	S170	R177W	177	Missense	distal	7	no	9.616	9.518	EPSD	TCGA;ICGC;COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	Q13009	TIAM1	P31749	AKT1	S170	K171E	171	Missense	proximal	1	no	9.616	9.452	EPSD	TCGA;ICGC;COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	Q13009	TIAM1	P31749	AKT1	S172	I175M	175	Missense	distal	3	no	13.600	13.646	EPSD	TCGA;ICGC;COSMIC	7.780	Up-regulation
AGC_Akt_AKT1_ST	Q13009	TIAM1	P31749	AKT1	S172	R169H	169	Missense	distal	-3	no	13.600	8.901	EPSD	TCGA;ICGC;COSMIC;CCLE	7.780	Down-regulation
AGC_Akt_AKT1_ST	Q13009	TIAM1	P31749	AKT1	S172	R177W	177	Missense	distal	5	no	13.600	13.505	EPSD	TCGA;ICGC;COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	Q13009	TIAM1	P31749	AKT1	S172	K171E	171	Missense	proximal	-1	no	13.600	13.579	EPSD	TCGA;ICGC;COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	Q13009	TIAM1	P31749	AKT1	S224	A218V	218	Missense	distal	-6	no	9.607	9.587	EPSD	TCGA	7.780	Down-regulation
AGC_Akt_AKT1_ST	Q13009	TIAM1	P31749	AKT1	S224	P220T	220	Missense	distal	-4	no	9.607	10.400	EPSD	TCGA;ICGC;COSMIC	7.780	Up-regulation
AGC_Akt_AKT1_ST	Q13009	TIAM1	P31749	AKT1	S224	P220L	220	Missense	distal	-4	no	9.607	9.220	EPSD	TCGA;ICGC;COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	Q13009	TIAM1	P31749	AKT1	S224	R217W	217	Missense	distal	-7	no	9.607	9.184	EPSD	TCGA;ICGC;COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	Q13009	TIAM1	P31749	AKT1	S224	P220Q	220	Missense	distal	-4	no	9.607	9.808	EPSD	TCGA;ICGC;COSMIC	7.780	Up-regulation
AGC_Akt_AKT1_ST	Q13009	TIAM1	P31749	AKT1	S224	C226W	226	Missense	proximal	2	no	9.607	9.805	EPSD	TCGA;ICGC;COSMIC	7.780	Up-regulation
AGC_Akt_AKT1_ST	Q13009	TIAM1	P31749	AKT1	S224	S231F	231	Missense	distal	7	no	9.607	9.534	EPSD	TCGA;ICGC;COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	Q13009	TIAM1	P31749	AKT1	S224	R221Q	221	Missense	distal	-3	no	9.607	2.396	EPSD	TCGA;ICGC;COSMIC	7.780	Loss
AGC_Akt_AKT1_ST	Q13009	TIAM1	P31749	AKT1	S231	Q238E	238	Missense	distal	7	no	11.969	11.984	PhosphoSitePlus	TCGA;ICGC;COSMIC	7.780	Up-regulation
AGC_Akt_AKT1_ST	Q13009	TIAM1	P31749	AKT1	S231	C226W	226	Missense	distal	-5	no	11.969	10.526	PhosphoSitePlus	TCGA;ICGC;COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	Q13009	TIAM1	P31749	AKT1	S231	S231F	231	Missense	central	0	yes	11.969	0.000	PhosphoSitePlus	TCGA;ICGC;COSMIC	7.780	Loss
AGC_Akt_AKT1_ST	Q13009	TIAM1	P31749	AKT1	T319	T319R	319	Missense	central	0	yes	11.997	0.000	EPSD	TCGA;ICGC;COSMIC	7.780	Loss
AGC_Akt_AKT1_ST	Q13009	TIAM1	P31749	AKT1	T319	Q313H	313	Missense	distal	-6	no	11.997	11.963	EPSD	TCGA;ICGC;COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	Q13009	TIAM1	P31749	AKT1	T319	A317T	317	Missense	proximal	-2	no	11.997	12.383	EPSD	TCGA;ICGC;COSMIC	7.780	Up-regulation
AGC_Akt_AKT1_ST	Q13009	TIAM1	P31749	AKT1	T320	T319R	319	Missense	proximal	-1	no	10.112	10.116	EPSD	TCGA;ICGC;COSMIC	7.780	Up-regulation
AGC_Akt_AKT1_ST	Q13009	TIAM1	P31749	AKT1	T320	Q313H	313	Missense	distal	-7	no	10.112	10.005	EPSD	TCGA;ICGC;COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	Q13009	TIAM1	P31749	AKT1	T320	A317T	317	Missense	distal	-3	no	10.112	9.393	EPSD	TCGA;ICGC;COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	Q13009	TIAM1	P31749	AKT1	T353	S350C	350	Missense	distal	-3	no	7.359	8.962	EPSD	TCGA;ICGC;COSMIC	7.780	Gain
AGC_Akt_AKT1_ST	Q13009	TIAM1	P31749	AKT1	S368	D369N	369	Missense	proximal	1	no	7.702	7.827	EPSD	TCGA;ICGC;COSMIC	7.780	Gain
AGC_Akt_AKT1_ST	Q13009	TIAM1	P31749	AKT1	T679	R678C	678	Missense	proximal	-1	no	9.345	9.275	EPSD	TCGA;ICGC;COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	Q13009	TIAM1	P31749	AKT1	T679	S685F	685	Missense	distal	6	no	9.345	9.225	EPSD	TCGA;ICGC;COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	Q13009	TIAM1	P31749	AKT1	T679	A686V	686	Missense	distal	7	no	9.345	9.341	EPSD	TCGA;ICGC;COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	Q13009	TIAM1	P31749	AKT1	T679	G674R	674	Missense	distal	-5	no	9.345	13.410	EPSD	TCGA;ICGC;COSMIC;CCLE	7.780	Up-regulation
AGC_Akt_AKT1_ST	Q13009	TIAM1	P31749	AKT1	S687	S685F	685	Missense	proximal	-2	no	11.534	10.667	EPSD	TCGA;ICGC;COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	Q13009	TIAM1	P31749	AKT1	S687	A686V	686	Missense	proximal	-1	no	11.534	11.520	EPSD	TCGA;ICGC;COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	Q13009	TIAM1	P31749	AKT1	S687	R690M	690	Missense	distal	3	no	11.534	11.466	EPSD	TCGA;ICGC;COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	Q13009	TIAM1	P31749	AKT1	S694	W697L	697	Missense	distal	3	no	8.523	8.553	EPSD	TCGA;ICGC;COSMIC	7.780	Up-regulation
AGC_Akt_AKT1_ST	Q13009	TIAM1	P31749	AKT1	S694	L699M	699	Missense	distal	5	no	8.523	8.532	EPSD	TCGA;ICGC	7.780	Up-regulation
AGC_Akt_AKT1_ST	Q13009	TIAM1	P31749	AKT1	S694	R690M	690	Missense	distal	-4	no	8.523	7.528	EPSD	TCGA;ICGC;COSMIC	7.780	Loss
AGC_Akt_AKT1_ST	Q13009	TIAM1	P31749	AKT1	S695	W697L	697	Missense	proximal	2	no	16.252	16.334	EPSD	TCGA;ICGC;COSMIC	7.780	Up-regulation
AGC_Akt_AKT1_ST	Q13009	TIAM1	P31749	AKT1	S695	L699M	699	Missense	distal	4	no	16.252	16.227	EPSD	TCGA;ICGC	7.780	Down-regulation
AGC_Akt_AKT1_ST	Q13009	TIAM1	P31749	AKT1	S695	R690M	690	Missense	distal	-5	no	16.252	11.730	EPSD	TCGA;ICGC;COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	Q13009	TIAM1	P31749	AKT1	S1036	R1042S	1042	Missense	distal	6	no	8.483	8.484	EPSD	TCGA;COSMIC	7.780	Up-regulation
AGC_Akt_AKT1_ST	Q13009	TIAM1	P31749	AKT1	S1036	R1042L	1042	Missense	distal	6	no	8.483	8.380	EPSD	TCGA;COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	Q13009	TIAM1	P31749	AKT1	S1036	R1042C	1042	Missense	distal	6	no	8.483	8.281	EPSD	TCGA;COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	Q13009	TIAM1	P31749	AKT1	S1036	K1043N	1043	Missense	distal	7	no	8.483	8.447	EPSD	TCGA	7.780	Down-regulation
AGC_Akt_AKT1_ST	Q13009	TIAM1	P31749	AKT1	S1036	R1042H	1042	Missense	distal	6	no	8.483	8.363	EPSD	TCGA;COSMIC;GDSC;CCLE	7.780	Down-regulation
AGC_Akt_AKT1_ST	Q13009	TIAM1	P31749	AKT1	S1143	F1145L	1145	Missense	proximal	2	no	9.376	9.408	EPSD	TCGA;COSMIC	7.780	Up-regulation
AGC_Akt_AKT1_ST	Q13009	TIAM1	P31749	AKT1	S1143	A1147T	1147	Missense	distal	4	no	9.376	9.247	EPSD	TCGA	7.780	Down-regulation
AGC_Akt_AKT1_ST	Q13009	TIAM1	P31749	AKT1	S1317	L1314R	1314	Missense	distal	-3	no	6.197	13.190	EPSD	TCGA	7.780	Gain
AGC_Akt_AKT1_ST	Q13009	TIAM1	P31749	AKT1	T1405	R1400G	1400	Missense	distal	-5	no	7.860	3.795	EPSD	TCGA;COSMIC	7.780	Loss
AGC_Akt_AKT1_ST	Q13009	TIAM1	P31749	AKT1	T1405	S1411Y	1411	Missense	distal	6	no	7.860	7.771	EPSD	TCGA;COSMIC	7.780	Loss
AGC_Akt_AKT1_ST	Q13009	TIAM1	P31749	AKT1	S1437	P1430L	1430	Missense	distal	-7	no	12.334	12.295	EPSD	TCGA;COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	Q13009	TIAM1	P31749	AKT1	S1437	S1442F	1442	Missense	distal	5	no	12.334	12.262	EPSD	TCGA;COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	Q13009	TIAM1	P31749	AKT1	S1437	V1436M	1436	Missense	proximal	-1	no	12.334	12.340	EPSD	TCGA;COSMIC	7.780	Up-regulation
AGC_Akt_AKT1_ST	Q13009	TIAM1	P31749	AKT1	S1532	G1539A	1539	Missense	distal	7	no	8.334	8.357	EPSD	TCGA;COSMIC	7.780	Up-regulation
AGC_Akt_AKT1_ST	Q13009	TIAM1	P31749	AKT1	S1532	R1538K	1538	Missense	distal	6	no	8.334	8.346	EPSD	TCGA;COSMIC	7.780	Up-regulation
AGC_Akt_AKT1_ST	O15151	MDM4	P31749	AKT1	T150	P156S	156	Missense	distal	6	no	13.761	13.854	EPSD	TCGA;ICGC;COSMIC	7.780	Up-regulation
AGC_Akt_AKT1_ST	O15151	MDM4	P31749	AKT1	T150	D154N	154	Missense	distal	4	no	13.761	13.646	EPSD	TCGA;ICGC;COSMIC;CCLE	7.780	Down-regulation
AGC_Akt_AKT1_ST	O15151	MDM4	P31749	AKT1	S291	S287C	287	Missense	distal	-4	no	8.920	7.327	EPSD	TCGA;ICGC;COSMIC	7.780	Loss
AGC_Akt_AKT1_ST	O15151	MDM4	P31749	AKT1	S342	T338P	338	Missense	distal	-4	no	9.130	8.338	EPSD	TCGA;COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	O15151	MDM4	P31749	AKT1	S344	T338P	338	Missense	distal	-6	no	8.555	8.460	EPSD	TCGA;COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	O15151	MDM4	P31749	AKT1	S367	V371I	371	Missense	distal	4	no	11.696	11.777	PhosphoSitePlus	TCGA;COSMIC	7.780	Up-regulation
AGC_Akt_AKT1_ST	O15151	MDM4	P31749	AKT1	S367	P369S	369	Missense	proximal	2	no	11.696	12.032	PhosphoSitePlus	TCGA;ICGC;COSMIC	7.780	Up-regulation
AGC_Akt_AKT1_ST	Q7Z5H3	ARHGAP22	P31749	AKT1	S14	Q8H	8	Missense	distal	-6	no	15.608	15.574	EPSD	TCGA;ICGC;COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	Q7Z5H3	ARHGAP22	P31749	AKT1	S14	R10K	10	Missense	distal	-4	no	15.608	15.595	EPSD	TCGA;ICGC;COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	Q7Z5H3	ARHGAP22	P31749	AKT1	S16	R10K	10	Missense	distal	-6	no	18.130	18.116	PhosphoSitePlus	TCGA;ICGC;COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	Q7Z5H3	ARHGAP22	P31749	AKT1	S128	L125R	125	Missense	distal	-3	no	5.203	12.197	EPSD	TCGA;ICGC;COSMIC	7.780	Gain
AGC_Akt_AKT1_ST	Q7Z5H3	ARHGAP22	P31749	AKT1	S636	E641K	641	Missense	distal	5	no	8.147	8.181	EPSD	TCGA;ICGC;COSMIC	7.780	Up-regulation
TK_Src_SrcB_LYN_Y	Q9GZY6	LAT2	P07948	LYN	Y110	P113H	113	Missense	distal	3	no	3.541	0.280	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	1.526	Loss
TK_Src_SrcB_LYN_Y	Q9GZY6	LAT2	P07948	LYN	Y118	R123W	123	Missense	distal	5	no	0.617	1.779	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	1.526	Gain
TK_Src_SrcB_LYN_Y	Q9GZY6	LAT2	P07948	LYN	Y136	D131E	131	Missense	distal	-5	no	3.254	4.585	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	1.526	Up-regulation
TK_Src_SrcB_LYN_Y	P30419	NMT1	P07948	LYN	Y41	S40I	40	Missense	proximal	-1	no	1.437	3.090	EPSD	TCGA;ICGC;COSMIC	1.526	Gain
TK_Src_SrcB_LYN_Y	P30419	NMT1	P07948	LYN	Y180	E178Q	178	Missense	proximal	-2	no	3.896	3.247	PhosphoSitePlus	TCGA;ICGC;COSMIC	1.526	Down-regulation
TK_Src_SrcB_LYN_Y	P30419	NMT1	P07948	LYN	Y180	Y173H	173	Missense	distal	-7	no	3.896	4.096	PhosphoSitePlus	TCGA;ICGC;COSMIC	1.526	Up-regulation
TK_Src_SrcB_LYN_Y	P02730	SLC4A1	P07948	LYN	Y8	E14D	14	Missense	distal	6	no	2.139	2.259	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	1.526	Up-regulation
TK_Src_SrcB_LYN_Y	P02730	SLC4A1	P07948	LYN	Y8	E2K	2	Missense	distal	-6	no	2.139	1.707	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	1.526	Down-regulation
TK_Src_SrcB_LYN_Y	P02730	SLC4A1	P07948	LYN	Y8	Q5R	5	Missense	distal	-3	no	2.139	1.399	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	1.526	Loss
TK_Src_SrcB_LYN_Y	P02730	SLC4A1	P07948	LYN	Y8	E13D	13	Missense	distal	5	no	2.139	3.278	EPSD;PhosphoSitePlus	TCGA;ICGC	1.526	Up-regulation
TK_Src_SrcB_LYN_Y	P02730	SLC4A1	P07948	LYN	Y21	L16M	16	Missense	distal	-5	no	3.161	3.656	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	1.526	Up-regulation
TK_Src_SrcB_LYN_Y	P02730	SLC4A1	P07948	LYN	Y21	E14D	14	Missense	distal	-7	no	3.161	3.056	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	1.526	Down-regulation
TK_Src_SrcB_LYN_Y	P02730	SLC4A1	P07948	LYN	Y21	E20K	20	Missense	proximal	-1	no	3.161	2.484	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	1.526	Down-regulation
TK_Src_SrcB_LYN_Y	P02730	SLC4A1	P07948	LYN	Y21	P24T	24	Missense	distal	3	no	3.161	1.505	EPSD;PhosphoSitePlus	TCGA;ICGC	1.526	Loss
TK_Src_SrcB_LYN_Y	P02730	SLC4A1	P07948	LYN	Y21	P24S	24	Missense	distal	3	no	3.161	0.818	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	1.526	Loss
TK_Src_SrcB_LYN_Y	P02730	SLC4A1	P07948	LYN	Y359	P354Q	354	Missense	distal	-5	no	5.387	4.589	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	1.526	Down-regulation
TK_Src_SrcB_LYN_Y	P25490	YY1	P07948	LYN	Y145	G141D	141	Missense	distal	-4	no	1.370	2.680	EPSD	TCGA;ICGC;COSMIC;GDSC;CCLE	1.526	Gain
TK_Src_SrcB_LYN_Y	P25490	YY1	P07948	LYN	Y254	S252L	252	Missense	proximal	-2	no	2.433	-0.436	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	1.526	Loss
TK_Src_SrcB_LYN_Y	P25490	YY1	P07948	LYN	Y254	S247L	247	Missense	distal	-7	no	2.433	2.313	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	1.526	Down-regulation
TK_Src_SrcB_LYN_Y	P25490	YY1	P07948	LYN	Y383	H377R	377	Missense	distal	-6	no	3.286	2.912	EPSD;PhosphoSitePlus	TCGA	1.526	Down-regulation
TK_Src_SrcB_LYN_Y	P25490	YY1	P07948	LYN	Y383	G379R	379	Missense	distal	-4	no	3.286	2.328	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC;GDSC;CCLE	1.526	Down-regulation
TK_Src_SrcB_LYN_Y	O43823	AKAP8	P07948	LYN	Y51	G54S	54	Missense	distal	3	no	5.524	5.827	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	1.526	Up-regulation
TK_Src_SrcB_LYN_Y	O43823	AKAP8	P07948	LYN	Y51	A56G	56	Missense	distal	5	no	5.524	6.621	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	1.526	Up-regulation
TK_Src_SrcB_LYN_Y	O43823	AKAP8	P07948	LYN	Y51	A49T	49	Missense	proximal	-2	no	5.524	5.812	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	1.526	Up-regulation
TK_Src_SrcB_LYN_Y	O43823	AKAP8	P07948	LYN	Y53	G54S	54	Missense	proximal	1	no	2.068	2.416	PhosphoSitePlus;EPSD	TCGA;ICGC;COSMIC	1.526	Up-regulation
TK_Src_SrcB_LYN_Y	O43823	AKAP8	P07948	LYN	Y53	A56G	56	Missense	distal	3	no	2.068	1.478	PhosphoSitePlus;EPSD	TCGA;ICGC;COSMIC	1.526	Loss
TK_Src_SrcB_LYN_Y	O43823	AKAP8	P07948	LYN	Y53	A49T	49	Missense	distal	-4	no	2.068	1.875	PhosphoSitePlus;EPSD	TCGA;ICGC;COSMIC	1.526	Down-regulation
TK_Src_SrcB_LYN_Y	O43823	AKAP8	P07948	LYN	Y53	A60V	60	Missense	distal	7	no	2.068	2.089	PhosphoSitePlus;EPSD	TCGA;ICGC	1.526	Up-regulation
TK_Src_SrcB_LYN_Y	O43823	AKAP8	P07948	LYN	Y80	A74S	74	Missense	distal	-6	no	1.900	2.003	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	1.526	Up-regulation
TK_Src_SrcB_LYN_Y	O43823	AKAP8	P07948	LYN	Y80	C85Y	85	Missense	distal	5	no	1.900	-0.286	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	1.526	Loss
TK_Src_SrcB_LYN_Y	O43823	AKAP8	P07948	LYN	Y146	E142K	142	Missense	distal	-4	no	4.024	3.651	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	1.526	Down-regulation
TK_Src_SrcB_LYN_Y	O43823	AKAP8	P07948	LYN	Y146	R147L	147	Missense	proximal	1	no	4.024	3.345	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	1.526	Down-regulation
TK_Src_SrcB_LYN_Y	O43823	AKAP8	P07948	LYN	Y146	P145L	145	Missense	proximal	-1	no	4.024	3.359	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	1.526	Down-regulation
TK_Src_SrcB_LYN_Y	O43823	AKAP8	P07948	LYN	Y146	Y152C	152	Missense	distal	6	no	4.024	3.816	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	1.526	Down-regulation
TK_Src_SrcB_LYN_Y	O43823	AKAP8	P07948	LYN	Y150	R147L	147	Missense	distal	-3	no	2.172	1.318	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	1.526	Loss
TK_Src_SrcB_LYN_Y	O43823	AKAP8	P07948	LYN	Y150	P145L	145	Missense	distal	-5	no	2.172	1.241	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	1.526	Loss
TK_Src_SrcB_LYN_Y	O43823	AKAP8	P07948	LYN	Y150	Y152C	152	Missense	proximal	2	no	2.172	1.169	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	1.526	Loss
TK_Src_SrcB_LYN_Y	O43823	AKAP8	P07948	LYN	Y154	R147L	147	Missense	distal	-7	no	2.317	2.170	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	1.526	Down-regulation
TK_Src_SrcB_LYN_Y	O43823	AKAP8	P07948	LYN	Y154	D161Y	161	Missense	distal	7	no	2.317	2.304	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	1.526	Down-regulation
TK_Src_SrcB_LYN_Y	O43823	AKAP8	P07948	LYN	Y154	Y152C	152	Missense	proximal	-2	no	2.317	-1.502	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	1.526	Loss
TK_Src_SrcB_LYN_Y	O43823	AKAP8	P07948	LYN	Y170	S171N	171	Missense	proximal	1	no	1.993	1.346	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	1.526	Loss
TK_Src_SrcB_LYN_Y	O43823	AKAP8	P07948	LYN	Y170	F166S	166	Missense	distal	-4	no	1.993	2.480	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	1.526	Up-regulation
TK_Src_SrcB_LYN_Y	O43823	AKAP8	P07948	LYN	Y311	L310P	310	Missense	proximal	-1	no	4.451	5.117	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	1.526	Up-regulation
TK_Src_SrcB_LYN_Y	O43823	AKAP8	P07948	LYN	Y311	P314A	314	Missense	distal	3	no	4.451	2.394	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	1.526	Down-regulation
TK_Src_SrcB_LYN_Y	P11274	BCR	P07948	LYN	Y279	Y283C	283	Missense	distal	4	no	2.613	2.596	EPSD	TCGA;ICGC;COSMIC	1.526	Down-regulation
TK_Src_SrcB_LYN_Y	P11274	BCR	P07948	LYN	Y279	Q277R	277	Missense	proximal	-2	no	2.613	3.434	EPSD	TCGA;ICGC;COSMIC	1.526	Up-regulation
TK_Src_SrcB_LYN_Y	P11274	BCR	P07948	LYN	Y279	P272S	272	Missense	distal	-7	no	2.613	2.487	EPSD	TCGA;ICGC;COSMIC	1.526	Down-regulation
TK_Src_SrcB_LYN_Y	P11274	BCR	P07948	LYN	Y283	Y283C	283	Missense	central	0	yes	2.669	0.000	EPSD	TCGA;ICGC;COSMIC	1.526	Loss
TK_Src_SrcB_LYN_Y	P11274	BCR	P07948	LYN	Y283	Q277R	277	Missense	distal	-6	no	2.669	2.448	EPSD	TCGA;ICGC;COSMIC	1.526	Down-regulation
TK_Src_SrcB_LYN_Y	P11274	BCR	P07948	LYN	Y283	M287V	287	Missense	distal	4	no	2.669	2.583	EPSD	TCGA;ICGC;COSMIC	1.526	Down-regulation
TK_Src_SrcB_LYN_Y	P11274	BCR	P07948	LYN	Y360	D365N	365	Missense	distal	5	no	2.787	2.641	EPSD	TCGA;ICGC	1.526	Down-regulation
TK_Src_SrcB_LYN_Y	P11274	BCR	P07948	LYN	Y561	H557R	557	Missense	distal	-4	no	2.514	1.492	EPSD	TCGA;ICGC;COSMIC	1.526	Loss
TK_Src_SrcB_LYN_Y	P11274	BCR	P07948	LYN	Y561	E555V	555	Missense	distal	-6	no	2.514	2.490	EPSD	TCGA;ICGC;COSMIC	1.526	Down-regulation
TK_Src_SrcB_LYN_Y	P11274	BCR	P07948	LYN	Y561	P566L	566	Missense	distal	5	no	2.514	3.180	EPSD	TCGA;ICGC;COSMIC	1.526	Up-regulation
TK_Src_SrcB_LYN_Y	P11274	BCR	P07948	LYN	Y561	R567C	567	Missense	distal	6	no	2.514	2.051	EPSD	TCGA;ICGC;COSMIC	1.526	Down-regulation
TK_Src_SrcB_LYN_Y	P11274	BCR	P07948	LYN	Y852	T845M	845	Missense	distal	-7	no	1.173	1.574	EPSD	TCGA;ICGC;COSMIC	1.526	Gain
TK_Src_SrcB_LYN_Y	P11274	BCR	P07948	LYN	Y910	D904N	904	Missense	distal	-6	no	2.129	2.155	EPSD	TCGA;ICGC;COSMIC	1.526	Up-regulation
TK_Src_SrcB_LYN_Y	P11274	BCR	P07948	LYN	Y910	V915A	915	Missense	distal	5	no	2.129	2.552	EPSD	TCGA;ICGC;COSMIC	1.526	Up-regulation
TK_Src_SrcB_LYN_Y	P11274	BCR	P07948	LYN	Y910	P907L	907	Missense	distal	-3	no	2.129	0.517	EPSD	TCGA;ICGC;COSMIC	1.526	Loss
TK_Src_SrcB_LYN_Y	O15492	RGS16	P07948	LYN	Y168	P169S	169	Missense	proximal	1	no	3.923	4.746	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	1.526	Up-regulation
TK_Src_SrcB_LYN_Y	O15492	RGS16	P07948	LYN	Y168	L162Q	162	Missense	distal	-6	no	3.923	4.398	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	1.526	Up-regulation
TK_Src_SrcB_LYN_Y	O15492	RGS16	P07948	LYN	Y168	S174L	174	Missense	distal	6	no	3.923	3.871	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	1.526	Down-regulation
TK_Src_SrcB_LYN_Y	O15492	RGS16	P07948	LYN	Y168	L162P	162	Missense	distal	-6	no	3.923	4.464	EPSD;PhosphoSitePlus	TCGA;ICGC	1.526	Up-regulation
TK_Src_SrcB_LYN_Y	O15492	RGS16	P07948	LYN	Y177	R178W	178	Missense	proximal	1	no	2.350	0.824	PhosphoSitePlus;EPSD	TCGA;ICGC;COSMIC	1.526	Loss
TK_Src_SrcB_LYN_Y	O15492	RGS16	P07948	LYN	Y177	S174L	174	Missense	distal	-3	no	2.350	0.902	PhosphoSitePlus;EPSD	TCGA;ICGC;COSMIC	1.526	Loss
TK_Src_SrcB_LYN_Y	Q06187	BTK	P07948	LYN	Y223	K218N	218	Missense	distal	-5	no	2.734	3.032	PhosphoSitePlus;EPSD	TCGA;ICGC;COSMIC	1.526	Up-regulation
TK_Src_SrcB_LYN_Y	Q06187	BTK	P07948	LYN	Y241	E246K	246	Missense	distal	5	no	0.933	2.610	EPSD	TCGA;ICGC;COSMIC	1.526	Gain
TK_Src_SrcB_LYN_Y	Q06187	BTK	P07948	LYN	Y551	D549N	549	Missense	proximal	-2	no	6.089	6.023	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	1.526	Down-regulation
TK_Src_SrcB_LYN_Y	P12318	FCGR2A	P07948	LYN	Y281	E282A	282	Missense	proximal	1	no	4.134	2.570	EPSD	TCGA;ICGC;COSMIC	1.526	Down-regulation
TK_Src_SrcB_LYN_Y	P12318	FCGR2A	P07948	LYN	Y281	D280E	280	Missense	proximal	-1	no	4.134	4.491	EPSD	TCGA;ICGC;COSMIC	1.526	Up-regulation
TK_Src_SrcB_LYN_Y	P12318	FCGR2A	P07948	LYN	Y281	T283A	283	Missense	proximal	2	no	4.134	4.116	EPSD	TCGA;ICGC;COSMIC	1.526	Down-regulation
TK_Src_SrcB_LYN_Y	P12318	FCGR2A	P07948	LYN	Y281	G287S	287	Missense	distal	6	no	4.134	4.187	EPSD	TCGA;ICGC;COSMIC	1.526	Up-regulation
TK_Src_SrcB_LYN_Y	P12318	FCGR2A	P07948	LYN	Y288	E282A	282	Missense	distal	-6	no	2.252	1.820	EPSD	TCGA;ICGC;COSMIC	1.526	Down-regulation
TK_Src_SrcB_LYN_Y	P12318	FCGR2A	P07948	LYN	Y288	T283A	283	Missense	distal	-5	no	2.252	0.652	EPSD	TCGA;ICGC;COSMIC	1.526	Loss
TK_Src_SrcB_LYN_Y	P12318	FCGR2A	P07948	LYN	Y288	G287S	287	Missense	proximal	-1	no	2.252	2.225	EPSD	TCGA;ICGC;COSMIC	1.526	Down-regulation
TK_Src_SrcB_LYN_Y	P32927	CSF2RB	P07948	LYN	Y468	I465V	465	Missense	distal	-3	no	0.824	1.897	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	1.526	Gain
TK_Src_SrcB_LYN_Y	P32927	CSF2RB	P07948	LYN	Y468	I465T	465	Missense	distal	-3	no	0.824	2.871	EPSD;PhosphoSitePlus	TCGA;COSMIC	1.526	Gain
TK_Src_SrcB_LYN_Y	P32927	CSF2RB	P07948	LYN	Y711	V707A	707	Missense	distal	-4	no	0.351	1.529	EPSD	TCGA;ICGC;COSMIC	1.526	Gain
TK_Src_SrcB_LYN_Y	P32927	CSF2RB	P07948	LYN	Y766	G765D	765	Missense	proximal	-1	no	0.489	1.958	EPSD	TCGA;COSMIC	1.526	Gain
TK_Src_SrcB_LYN_Y	P32927	CSF2RB	P07948	LYN	Y822	D821N	821	Missense	proximal	-1	no	3.906	3.707	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	1.526	Down-regulation
TK_Src_SrcB_LYN_Y	P32927	CSF2RB	P07948	LYN	Y822	G820D	820	Missense	proximal	-2	no	3.906	4.405	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	1.526	Up-regulation
TK_Src_SrcB_LYN_Y	P32927	CSF2RB	P07948	LYN	Y822	P826L	826	Missense	distal	4	no	3.906	3.620	EPSD;PhosphoSitePlus	TCGA;COSMIC	1.526	Down-regulation
TK_Src_SrcB_LYN_Y	P32927	CSF2RB	P07948	LYN	Y822	V815D	815	Missense	distal	-7	no	3.906	4.037	EPSD;PhosphoSitePlus	TCGA;COSMIC	1.526	Up-regulation
TK_Src_SrcB_LYN_Y	P15391	CD19	P07948	LYN	Y348	V351M	351	Missense	distal	3	no	2.608	2.866	EPSD	TCGA;ICGC;COSMIC	1.526	Up-regulation
TK_Src_SrcB_LYN_Y	P15391	CD19	P07948	LYN	Y378	V385I	385	Missense	distal	7	no	3.346	3.368	EPSD	TCGA;ICGC;COSMIC	1.526	Up-regulation
TK_Src_SrcB_LYN_Y	P15391	CD19	P07948	LYN	Y378	P376R	376	Missense	proximal	-2	no	3.346	3.496	EPSD	TCGA;ICGC;COSMIC	1.526	Up-regulation
TK_Src_SrcB_LYN_Y	P15391	CD19	P07948	LYN	Y409	G408D	408	Missense	proximal	-1	no	3.627	5.096	EPSD	TCGA;ICGC;COSMIC	1.526	Up-regulation
TK_Src_SrcB_LYN_Y	P15391	CD19	P07948	LYN	Y439	P446L	446	Missense	distal	7	no	2.774	2.852	EPSD	TCGA;ICGC;COSMIC	1.526	Up-regulation
TK_Src_SrcB_LYN_Y	P15391	CD19	P07948	LYN	Y531	E526K	526	Missense	distal	-5	no	6.658	5.832	PhosphoSitePlus;EPSD	TCGA;COSMIC	1.526	Down-regulation
TK_Src_SrcB_LYN_Y	P07948	LYN	P07948	LYN	Y397	K404N	404	Missense	distal	7	no	8.295	8.262	PhosphoSitePlus;EPSD	TCGA;ICGC;COSMIC	1.526	Down-regulation
TK_Src_SrcB_LYN_Y	Q13263	TRIM28	P07948	LYN	Y449	M443I	443	Missense	distal	-6	no	3.114	2.705	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	1.526	Down-regulation
TK_Src_SrcB_LYN_Y	Q13263	TRIM28	P07948	LYN	Y458	S459T	459	Missense	proximal	1	no	1.495	1.764	EPSD;PhosphoSitePlus	TCGA;ICGC	1.526	Gain
TK_Src_SrcB_LYN_Y	Q14790	CASP8	P07948	LYN	Y380	S375F	375	Missense	distal	-5	no	5.343	5.132	PhosphoSitePlus;EPSD	TCGA;COSMIC	1.526	Down-regulation
TK_Src_SrcB_LYN_Y	Q14790	CASP8	P07948	LYN	Y448	D454H	454	Missense	distal	6	no	3.836	3.646	EPSD;PhosphoSitePlus	TCGA	1.526	Down-regulation
TK_Src_SrcB_LYN_Y	Q14790	CASP8	P07948	LYN	Y448	D454N	454	Missense	distal	6	no	3.836	3.835	EPSD;PhosphoSitePlus	TCGA;COSMIC	1.526	Down-regulation
TK_Src_SrcB_LYN_Y	P29350	PTPN6	P07948	LYN	Y306	I307M	307	Missense	proximal	1	no	2.085	1.965	EPSD	TCGA;COSMIC	1.526	Down-regulation
TK_Src_SrcB_LYN_Y	P29350	PTPN6	P07948	LYN	Y306	A304T	304	Missense	proximal	-2	no	2.085	2.373	EPSD	TCGA;COSMIC	1.526	Up-regulation
TK_Src_SrcB_LYN_Y	P29350	PTPN6	P07948	LYN	Y377	P376L	376	Missense	proximal	-1	no	2.801	2.135	EPSD	TCGA;COSMIC	1.526	Down-regulation
TK_Src_SrcB_LYN_Y	P29350	PTPN6	P07948	LYN	Y564	E561Q	561	Missense	distal	-3	no	4.298	3.350	EPSD	TCGA;ICGC;COSMIC	1.526	Down-regulation
TK_Src_SrcB_LYN_Y	P46527	CDKN1B	P07948	LYN	Y74	G72D	72	Missense	proximal	-2	no	1.475	1.975	EPSD	TCGA;ICGC;COSMIC	1.526	Gain
TK_Src_SrcB_LYN_Y	P46527	CDKN1B	P07948	LYN	Y88	K81R	81	Missense	distal	-7	no	4.687	4.686	PhosphoSitePlus	TCGA;ICGC;COSMIC	1.526	Down-regulation
TK_Src_SrcB_LYN_Y	P60484	PTEN	P07948	LYN	Y27	L25V	25	Missense	proximal	-2	no	1.661	1.918	EPSD	TCGA;GDSC;CCLE	1.526	Up-regulation
TK_Src_SrcB_LYN_Y	P60484	PTEN	P07948	LYN	Y27	Y27C	27	Missense	central	0	yes	1.661	0.000	EPSD	TCGA;ICGC;COSMIC	1.526	Loss
TK_Src_SrcB_LYN_Y	P60484	PTEN	P07948	LYN	Y27	Y27D	27	Missense	central	0	yes	1.661	0.000	EPSD	TCGA;ICGC;COSMIC	1.526	Loss
TK_Src_SrcB_LYN_Y	P60484	PTEN	P07948	LYN	Y27	L25F	25	Missense	proximal	-2	no	1.661	1.460	EPSD	TCGA;ICGC;COSMIC	1.526	Loss
TK_Src_SrcB_LYN_Y	P60484	PTEN	P07948	LYN	Y27	D24G	24	Missense	distal	-3	no	1.661	1.140	EPSD	TCGA;ICGC;COSMIC	1.526	Loss
TK_Src_SrcB_LYN_Y	P60484	PTEN	P07948	LYN	Y27	Y29S	29	Missense	proximal	2	no	1.661	1.590	EPSD	TCGA;ICGC;COSMIC	1.526	Down-regulation
TK_Src_SrcB_LYN_Y	P60484	PTEN	P07948	LYN	Y27	D24E	24	Missense	distal	-3	no	1.661	2.586	EPSD	TCGA;ICGC;COSMIC	1.526	Up-regulation
TK_Src_SrcB_LYN_Y	P60484	PTEN	P07948	LYN	Y27	D24V	24	Missense	distal	-3	no	1.661	1.875	EPSD	TCGA;ICGC;COSMIC	1.526	Up-regulation
TK_Src_SrcB_LYN_Y	P60484	PTEN	P07948	LYN	Y27	I28S	28	Missense	proximal	1	no	1.661	2.237	EPSD	TCGA;ICGC;COSMIC	1.526	Up-regulation
TK_Src_SrcB_LYN_Y	P60484	PTEN	P07948	LYN	Y27	A34T	34	Missense	distal	7	no	1.661	1.631	EPSD	TCGA;ICGC;COSMIC	1.526	Down-regulation
TK_Src_SrcB_LYN_Y	P60484	PTEN	P07948	LYN	Y27	I28T	28	Missense	proximal	1	no	1.661	2.505	EPSD	TCGA;ICGC;COSMIC	1.526	Up-regulation
TK_Src_SrcB_LYN_Y	P60484	PTEN	P07948	LYN	Y27	A34V	34	Missense	distal	7	no	1.661	1.682	EPSD	TCGA;ICGC;COSMIC	1.526	Up-regulation
TK_Src_SrcB_LYN_Y	P60484	PTEN	P07948	LYN	Y27	P30Q	30	Missense	distal	3	no	1.661	-0.962	EPSD	TCGA;ICGC;COSMIC	1.526	Loss
TK_Src_SrcB_LYN_Y	P60484	PTEN	P07948	LYN	Y27	A34S	34	Missense	distal	7	no	1.661	1.629	EPSD	TCGA;ICGC;COSMIC;CCLE	1.526	Down-regulation
TK_Src_SrcB_LYN_Y	P60484	PTEN	P07948	LYN	Y27	D24H	24	Missense	distal	-3	no	1.661	1.924	EPSD	TCGA;ICGC;COSMIC	1.526	Up-regulation
TK_Src_SrcB_LYN_Y	P60484	PTEN	P07948	LYN	Y46	N48I	48	Missense	proximal	2	no	2.264	1.667	EPSD	TCGA;ICGC;COSMIC	1.526	Down-regulation
TK_Src_SrcB_LYN_Y	P60484	PTEN	P07948	LYN	Y46	E43K	43	Missense	distal	-3	no	2.264	1.745	EPSD	TCGA;ICGC;COSMIC	1.526	Down-regulation
TK_Src_SrcB_LYN_Y	P60484	PTEN	P07948	LYN	Y46	Y46H	46	Missense	central	0	yes	2.264	0.000	EPSD	TCGA;ICGC;COSMIC;CCLE	1.526	Loss
TK_Src_SrcB_LYN_Y	P60484	PTEN	P07948	LYN	Y46	G44D	44	Missense	proximal	-2	no	2.264	2.763	EPSD	TCGA;ICGC;COSMIC	1.526	Up-regulation
TK_Src_SrcB_LYN_Y	P60484	PTEN	P07948	LYN	Y46	L42V	42	Missense	distal	-4	no	2.264	2.345	EPSD	TCGA;ICGC;COSMIC	1.526	Up-regulation
TK_Src_SrcB_LYN_Y	P60484	PTEN	P07948	LYN	Y46	N48K	48	Missense	proximal	2	no	2.264	2.122	EPSD	TCGA;ICGC;COSMIC	1.526	Down-regulation
TK_Src_SrcB_LYN_Y	P60484	PTEN	P07948	LYN	Y46	R47K	47	Missense	proximal	1	no	2.264	2.095	EPSD	TCGA;ICGC;COSMIC	1.526	Down-regulation
TK_Src_SrcB_LYN_Y	P60484	PTEN	P07948	LYN	Y46	R47M	47	Missense	proximal	1	no	2.264	1.873	EPSD	TCGA;ICGC;COSMIC	1.526	Down-regulation
TK_Src_SrcB_LYN_Y	P60484	PTEN	P07948	LYN	Y46	A39P	39	Missense	distal	-7	no	2.264	2.292	EPSD	TCGA;ICGC;COSMIC	1.526	Up-regulation
TK_Src_SrcB_LYN_Y	P60484	PTEN	P07948	LYN	Y46	N49T	49	Missense	distal	3	no	2.264	1.841	EPSD	TCGA;ICGC;COSMIC	1.526	Down-regulation
TK_Src_SrcB_LYN_Y	P60484	PTEN	P07948	LYN	Y178	R173C	173	Missense	distal	-5	no	4.329	3.745	EPSD	TCGA;ICGC;COSMIC;GDSC;CCLE	1.526	Down-regulation
TK_Src_SrcB_LYN_Y	P60484	PTEN	P07948	LYN	Y178	R173H	173	Missense	distal	-5	no	4.329	3.651	EPSD	TCGA;ICGC;COSMIC;GDSC;CCLE	1.526	Down-regulation
TK_Src_SrcB_LYN_Y	P60484	PTEN	P07948	LYN	Y178	Y178C	178	Missense	central	0	yes	4.329	0.000	EPSD	TCGA;ICGC;COSMIC	1.526	Loss
TK_Src_SrcB_LYN_Y	P60484	PTEN	P07948	LYN	Y178	Q171K	171	Missense	distal	-7	no	4.329	4.368	EPSD	TCGA;ICGC;COSMIC	1.526	Up-regulation
TK_Src_SrcB_LYN_Y	P60484	PTEN	P07948	LYN	Y178	Y177F	177	Missense	proximal	-1	no	4.329	4.654	EPSD	TCGA;ICGC;COSMIC	1.526	Up-regulation
TK_Src_SrcB_LYN_Y	P60484	PTEN	P07948	LYN	Y178	Q171R	171	Missense	distal	-7	no	4.329	4.367	EPSD	TCGA;ICGC;COSMIC	1.526	Up-regulation
TK_Src_SrcB_LYN_Y	P60484	PTEN	P07948	LYN	Y178	R173L	173	Missense	distal	-5	no	4.329	3.111	EPSD	TCGA;ICGC;COSMIC	1.526	Down-regulation
TK_Src_SrcB_LYN_Y	P60484	PTEN	P07948	LYN	Y178	L181P	181	Missense	distal	3	no	4.329	4.979	EPSD	TCGA;ICGC;COSMIC	1.526	Up-regulation
TK_Src_SrcB_LYN_Y	P60484	PTEN	P07948	LYN	Y178	Q171E	171	Missense	distal	-7	no	4.329	4.675	EPSD	TCGA;ICGC;COSMIC	1.526	Up-regulation
TK_Src_SrcB_LYN_Y	P60484	PTEN	P07948	LYN	Y178	Y177D	177	Missense	proximal	-1	no	4.329	5.114	EPSD	TCGA;ICGC;COSMIC	1.526	Up-regulation
TK_Src_SrcB_LYN_Y	P60484	PTEN	P07948	LYN	Y240	Q245P	245	Missense	distal	5	no	1.505	2.446	PhosphoSitePlus	TCGA;ICGC;COSMIC	1.526	Gain
TK_Src_SrcB_LYN_Y	P60484	PTEN	P07948	LYN	Y240	Q245E	245	Missense	distal	5	no	1.505	1.672	PhosphoSitePlus	TCGA;ICGC;COSMIC	1.526	Gain
TK_Src_SrcB_LYN_Y	P60484	PTEN	P07948	LYN	Y240	F241S	241	Missense	proximal	1	no	1.505	1.527	PhosphoSitePlus	TCGA;ICGC;COSMIC;CCLE	1.526	Gain
TK_Src_SrcB_LYN_Y	P60484	PTEN	P07948	LYN	Y315	D312N	312	Missense	distal	-3	no	3.455	3.414	EPSD	TCGA;ICGC;COSMIC	1.526	Down-regulation
TK_Src_SrcB_LYN_Y	P60484	PTEN	P07948	LYN	Y315	K322E	322	Missense	distal	7	no	3.455	3.414	EPSD	TCGA;ICGC;COSMIC	1.526	Down-regulation
TK_Src_SrcB_LYN_Y	P60484	PTEN	P07948	LYN	Y315	D310G	310	Missense	distal	-5	no	3.455	3.883	EPSD	TCGA;ICGC;COSMIC;GDSC;CCLE	1.526	Up-regulation
TK_Src_SrcB_LYN_Y	P60484	PTEN	P07948	LYN	Y315	R308C	308	Missense	distal	-7	no	3.455	3.083	EPSD	TCGA;ICGC;COSMIC	1.526	Down-regulation
TK_Src_SrcB_LYN_Y	P60484	PTEN	P07948	LYN	Y315	L320S	320	Missense	distal	5	no	3.455	2.400	EPSD	TCGA;ICGC;COSMIC	1.526	Down-regulation
TK_Src_SrcB_LYN_Y	P60484	PTEN	P07948	LYN	Y377	E373K	373	Missense	distal	-4	no	3.487	3.114	EPSD	TCGA;ICGC	1.526	Down-regulation
TK_Src_SrcB_LYN_Y	P60484	PTEN	P07948	LYN	Y377	N372D	372	Missense	distal	-5	no	3.487	2.683	EPSD	TCGA;ICGC;COSMIC	1.526	Down-regulation
TK_Src_SrcB_LYN_Y	P60484	PTEN	P07948	LYN	Y379	E373K	373	Missense	distal	-6	no	1.716	1.284	EPSD	TCGA;ICGC	1.526	Loss
TK_Src_SrcB_LYN_Y	P60484	PTEN	P07948	LYN	Y379	N372D	372	Missense	distal	-7	no	1.716	1.816	EPSD	TCGA;ICGC;COSMIC	1.526	Up-regulation
TK_Src_SrcB_LYN_Y	P22681	CBL	P07948	LYN	Y141	R139I	139	Missense	proximal	-2	no	2.213	-0.417	EPSD	TCGA;ICGC;COSMIC	1.526	Loss
TK_Src_SrcB_LYN_Y	P22681	CBL	P07948	LYN	Y141	E143D	143	Missense	proximal	2	no	2.213	1.976	EPSD	TCGA;ICGC	1.526	Down-regulation
TK_Src_SrcB_LYN_Y	P22681	CBL	P07948	LYN	Y371	Q367H	367	Missense	distal	-4	no	2.726	1.409	PhosphoSitePlus	TCGA;ICGC;COSMIC	1.526	Loss
TK_Src_SrcB_LYN_Y	P22681	CBL	P07948	LYN	Y371	L370S	370	Missense	proximal	-1	no	2.726	2.086	PhosphoSitePlus	TCGA;ICGC	1.526	Down-regulation
TK_Src_SrcB_LYN_Y	P22681	CBL	P07948	LYN	Y774	D772Y	772	Missense	proximal	-2	no	2.517	1.605	EPSD	TCGA;ICGC;COSMIC	1.526	Down-regulation
TK_Src_SrcB_LYN_Y	P22681	CBL	P07948	LYN	Y774	D775V	775	Missense	proximal	1	no	2.517	3.392	EPSD	TCGA;ICGC;COSMIC	1.526	Up-regulation
TK_Src_SrcB_LYN_Y	P14317	HCLS1	P07948	LYN	Y83	E90Q	90	Missense	distal	7	no	1.814	1.777	EPSD	TCGA;ICGC;COSMIC	1.526	Down-regulation
TK_Src_SrcB_LYN_Y	P14317	HCLS1	P07948	LYN	Y83	G85S	85	Missense	proximal	2	no	1.814	1.915	EPSD	TCGA;ICGC;COSMIC	1.526	Up-regulation
TK_Src_SrcB_LYN_Y	P14317	HCLS1	P07948	LYN	Y83	R86W	86	Missense	distal	3	no	1.814	3.689	EPSD	TCGA;ICGC;COSMIC	1.526	Up-regulation
TK_Src_SrcB_LYN_Y	P14317	HCLS1	P07948	LYN	Y153	G156C	156	Missense	distal	3	no	1.178	2.800	EPSD	TCGA;ICGC;COSMIC	1.526	Gain
TK_Src_SrcB_LYN_Y	P14317	HCLS1	P07948	LYN	Y190	E185K	185	Missense	distal	-5	no	2.670	1.844	EPSD	TCGA;ICGC;COSMIC	1.526	Down-regulation
TK_Src_SrcB_LYN_Y	P14317	HCLS1	P07948	LYN	Y190	A191T	191	Missense	proximal	1	no	2.670	3.989	EPSD	TCGA;ICGC;COSMIC	1.526	Up-regulation
TK_Src_SrcB_LYN_Y	P14317	HCLS1	P07948	LYN	Y190	R188I	188	Missense	proximal	-2	no	2.670	0.039	EPSD	TCGA;ICGC;COSMIC	1.526	Loss
TK_Src_SrcB_LYN_Y	P14317	HCLS1	P07948	LYN	Y222	E216K	216	Missense	distal	-6	no	5.208	4.776	PhosphoSitePlus	TCGA;ICGC;COSMIC	1.526	Down-regulation
TK_Src_SrcB_LYN_Y	P14317	HCLS1	P07948	LYN	Y222	A221V	221	Missense	proximal	-1	no	5.208	5.562	PhosphoSitePlus	TCGA;ICGC;COSMIC	1.526	Up-regulation
TK_Src_SrcB_LYN_Y	P14317	HCLS1	P07948	LYN	Y360	Y360C	360	Missense	central	0	yes	1.772	0.000	EPSD	TCGA;ICGC;COSMIC	1.526	Loss
TK_Src_SrcB_LYN_Y	P14317	HCLS1	P07948	LYN	Y360	E356A	356	Missense	distal	-4	no	1.772	1.840	EPSD	TCGA;ICGC	1.526	Up-regulation
TK_Src_SrcB_LYN_Y	P14317	HCLS1	P07948	LYN	Y378	E375K	375	Missense	distal	-3	no	4.497	3.978	EPSD	TCGA;ICGC;COSMIC	1.526	Down-regulation
TK_Src_SrcB_LYN_Y	P14317	HCLS1	P07948	LYN	Y378	E373D	373	Missense	distal	-5	no	4.497	3.165	EPSD	TCGA;ICGC;COSMIC	1.526	Down-regulation
TK_Src_SrcB_LYN_Y	P14317	HCLS1	P07948	LYN	Y378	D380Y	380	Missense	proximal	2	no	4.497	4.421	EPSD	TCGA;ICGC;COSMIC	1.526	Down-regulation
TK_Src_SrcB_LYN_Y	P14317	HCLS1	P07948	LYN	Y378	P372L	372	Missense	distal	-6	no	4.497	3.956	EPSD	TCGA;ICGC;COSMIC	1.526	Down-regulation
TK_Src_SrcB_LYN_Y	P14317	HCLS1	P07948	LYN	Y378	E373K	373	Missense	distal	-5	no	4.497	3.671	EPSD	TCGA	1.526	Down-regulation
TK_Src_SrcB_LYN_Y	P14317	HCLS1	P07948	LYN	Y397	D391N	391	Missense	distal	-6	no	4.274	4.300	EPSD	TCGA;ICGC;COSMIC	1.526	Up-regulation
TK_Src_SrcB_LYN_Y	P14317	HCLS1	P07948	LYN	Y397	Y397S	397	Missense	central	0	yes	4.274	0.000	EPSD	TCGA;ICGC;COSMIC	1.526	Loss
TK_Src_SrcB_LYN_Y	P14317	HCLS1	P07948	LYN	Y397	E398K	398	Missense	proximal	1	no	4.274	3.287	EPSD	TCGA;ICGC;COSMIC	1.526	Down-regulation
TK_Src_SrcB_LYN_Y	O14920	IKBKB	P07948	LYN	Y188	V183M	183	Missense	distal	-5	no	2.113	1.638	PhosphoSitePlus;EPSD	TCGA;COSMIC	1.526	Down-regulation
TK_Src_SrcB_LYN_Y	O14920	IKBKB	P07948	LYN	Y199	V203I	203	Missense	distal	4	no	2.659	2.744	EPSD;PhosphoSitePlus	TCGA;COSMIC	1.526	Up-regulation
TK_Src_SrcB_LYN_Y	Q9H792	PEAK1	P07948	LYN	Y387	S389T	389	Missense	proximal	2	no	1.850	1.956	EPSD	TCGA	1.526	Up-regulation
TK_Src_SrcB_LYN_Y	Q9H792	PEAK1	P07948	LYN	Y616	T615A	615	Missense	proximal	-1	no	2.500	0.882	EPSD	TCGA;ICGC;COSMIC	1.526	Loss
TK_Src_SrcB_LYN_Y	Q9H792	PEAK1	P07948	LYN	Y635	A639P	639	Missense	distal	4	no	1.480	1.698	PhosphoSitePlus	TCGA;ICGC;COSMIC	1.526	Gain
TK_Src_SrcB_LYN_Y	Q9H792	PEAK1	P07948	LYN	Y641	A639P	639	Missense	proximal	-2	no	2.036	2.290	EPSD	TCGA;ICGC;COSMIC	1.526	Up-regulation
TK_Src_SrcB_LYN_Y	Q9H792	PEAK1	P07948	LYN	Y641	I640V	640	Missense	proximal	-1	no	2.036	1.172	EPSD	TCGA;ICGC;COSMIC	1.526	Loss
TK_Src_SrcB_LYN_Y	Q9H792	PEAK1	P07948	LYN	Y880	S878F	878	Missense	proximal	-2	no	2.188	-0.882	EPSD	TCGA;ICGC;COSMIC	1.526	Loss
TK_Src_SrcB_LYN_Y	Q9H792	PEAK1	P07948	LYN	Y880	R874C	874	Missense	distal	-6	no	2.188	1.785	EPSD	TCGA;ICGC;COSMIC	1.526	Down-regulation
TK_Src_SrcB_LYN_Y	Q9H792	PEAK1	P07948	LYN	Y880	P879L	879	Missense	proximal	-1	no	2.188	1.522	EPSD	TCGA;ICGC;COSMIC	1.526	Loss
TK_Src_SrcB_LYN_Y	Q9H792	PEAK1	P07948	LYN	Y880	L885I	885	Missense	distal	5	no	2.188	2.144	EPSD	TCGA;ICGC;COSMIC	1.526	Down-regulation
TK_Src_SrcB_LYN_Y	Q9H792	PEAK1	P07948	LYN	Y1215	S1217F	1217	Missense	proximal	2	no	2.268	2.473	EPSD	TCGA;ICGC;COSMIC	1.526	Up-regulation
TK_Src_SrcB_LYN_Y	Q9H792	PEAK1	P07948	LYN	Y1372	V1377F	1377	Missense	distal	5	no	2.096	2.581	EPSD	TCGA;ICGC;COSMIC	1.526	Up-regulation
TK_Src_SrcB_LYN_Y	Q9H792	PEAK1	P07948	LYN	Y1372	H1373R	1373	Missense	proximal	1	no	2.096	1.646	EPSD	TCGA;ICGC;COSMIC	1.526	Down-regulation
TK_Src_SrcB_LYN_Y	Q9H792	PEAK1	P07948	LYN	Y1620	R1622Q	1622	Missense	proximal	2	no	3.096	3.292	EPSD	TCGA;ICGC;COSMIC	1.526	Up-regulation
TK_Src_SrcB_LYN_Y	Q9H792	PEAK1	P07948	LYN	Y1620	R1627C	1627	Missense	distal	7	no	3.096	3.194	EPSD	TCGA;ICGC;COSMIC	1.526	Up-regulation
TK_Src_SrcB_LYN_Y	P11802	CDK4	P07948	LYN	Y17	R24L	24	Missense	distal	7	no	3.291	3.332	PhosphoSitePlus	TCGA;ICGC;COSMIC	1.526	Up-regulation
TK_Src_SrcB_LYN_Y	P11802	CDK4	P07948	LYN	Y17	A23S	23	Missense	distal	6	no	3.291	3.276	PhosphoSitePlus	TCGA;ICGC;COSMIC	1.526	Down-regulation
TK_Src_SrcB_LYN_Y	P11802	CDK4	P07948	LYN	Y17	G15R	15	Missense	proximal	-2	no	3.291	3.788	PhosphoSitePlus	TCGA;ICGC;COSMIC	1.526	Up-regulation
TK_Src_SrcB_LYN_Y	P11802	CDK4	P07948	LYN	Y17	K22M	22	Missense	distal	5	no	3.291	2.532	PhosphoSitePlus	TCGA;ICGC;COSMIC	1.526	Down-regulation
TK_Src_SrcB_LYN_Y	P11802	CDK4	P07948	LYN	Y17	R24H	24	Missense	distal	7	no	3.291	3.341	PhosphoSitePlus	TCGA;ICGC;COSMIC;GDSC;CCLE	1.526	Up-regulation
TK_Src_SrcB_LYN_Y	P11802	CDK4	P07948	LYN	Y17	R24S	24	Missense	distal	7	no	3.291	3.248	PhosphoSitePlus	TCGA;ICGC;COSMIC	1.526	Down-regulation
TK_Src_SrcB_LYN_Y	P11802	CDK4	P07948	LYN	Y17	R24C	24	Missense	distal	7	no	3.291	3.389	PhosphoSitePlus	TCGA;ICGC;COSMIC;GDSC;CCLE	1.526	Up-regulation
TK_Src_SrcB_LYN_Y	P11802	CDK4	P07948	LYN	Y17	K22Q	22	Missense	distal	5	no	3.291	1.447	PhosphoSitePlus	TCGA;ICGC;COSMIC;GDSC;CCLE	1.526	Loss
TK_Src_SrcB_LYN_Y	P42768	WAS	P07948	LYN	Y54	A56V	56	Missense	proximal	2	no	2.706	2.488	EPSD	TCGA;ICGC;COSMIC	1.526	Down-regulation
TK_Src_SrcB_LYN_Y	P42768	WAS	P07948	LYN	Y102	Q104H	104	Missense	proximal	2	no	2.571	2.263	EPSD	TCGA;ICGC;COSMIC	1.526	Down-regulation
TK_Src_SrcB_LYN_Y	P42768	WAS	P07948	LYN	Y102	E98V	98	Missense	distal	-4	no	2.571	1.461	EPSD	TCGA;ICGC;COSMIC	1.526	Loss
TK_Src_SrcB_LYN_Y	P42768	WAS	P07948	LYN	Y102	L105I	105	Missense	distal	3	no	2.571	2.313	EPSD	TCGA;ICGC	1.526	Down-regulation
TK_Src_SrcB_LYN_Y	P42768	WAS	P07948	LYN	Y212	R213C	213	Missense	proximal	1	no	3.424	3.515	EPSD	TCGA;ICGC;COSMIC	1.526	Up-regulation
TK_Src_SrcB_LYN_Y	P42768	WAS	P07948	LYN	Y212	Y212F	212	Missense	central	0	yes	3.424	0.000	EPSD	TCGA;ICGC;COSMIC	1.526	Loss
TK_Src_SrcB_LYN_Y	P42768	WAS	P07948	LYN	Y212	R211Q	211	Missense	proximal	-1	no	3.424	4.593	EPSD	TCGA;ICGC;COSMIC	1.526	Up-regulation
TK_Src_SrcB_LYN_Y	P42768	WAS	P07948	LYN	Y291	D292N	292	Missense	proximal	1	no	1.806	1.817	PhosphoSitePlus	TCGA;ICGC;COSMIC	1.526	Up-regulation
TK_Src_SrcB_LYN_Y	P42768	WAS	P07948	LYN	Y291	F293L	293	Missense	proximal	2	no	1.806	1.433	PhosphoSitePlus	TCGA;ICGC;COSMIC	1.526	Loss
TK_Src_SrcB_LYN_Y	P33993	MCM7	P07948	LYN	Y126	P122R	122	Missense	distal	-4	no	1.746	1.428	EPSD	TCGA;ICGC;COSMIC	1.526	Loss
TK_Src_SrcB_LYN_Y	P33993	MCM7	P07948	LYN	Y126	A128T	128	Missense	proximal	2	no	1.746	1.764	EPSD	TCGA;ICGC;COSMIC	1.526	Up-regulation
TK_Src_SrcB_LYN_Y	P33993	MCM7	P07948	LYN	Y126	Q123H	123	Missense	distal	-3	no	1.746	2.032	EPSD	TCGA;ICGC	1.526	Up-regulation
TK_Src_SrcB_LYN_Y	P33993	MCM7	P07948	LYN	Y137	G140R	140	Missense	distal	3	no	0.411	1.618	EPSD	TCGA;ICGC;COSMIC	1.526	Gain
TK_Src_SrcB_LYN_Y	Q9UN19	DAPP1	P07948	LYN	Y139	S141F	141	Missense	proximal	2	no	8.133	8.339	PhosphoSitePlus	TCGA;ICGC;COSMIC	1.526	Up-regulation
TK_Src_SrcB_LYN_Y	Q9UN19	DAPP1	P07948	LYN	Y139	V144A	144	Missense	distal	5	no	8.133	8.556	PhosphoSitePlus	TCGA;ICGC;COSMIC	1.526	Up-regulation
TK_Src_SrcB_LYN_Y	Q9UN19	DAPP1	P07948	LYN	Y139	E135K	135	Missense	distal	-4	no	8.133	7.760	PhosphoSitePlus	TCGA;ICGC;COSMIC	1.526	Down-regulation
TK_Src_SrcB_LYN_Y	Q9UN19	DAPP1	P07948	LYN	Y139	S141Y	141	Missense	proximal	2	no	8.133	8.204	PhosphoSitePlus	TCGA;ICGC;COSMIC	1.526	Up-regulation
TK_Src_SrcB_LYN_Y	P35354	PTGS2	P07948	LYN	Y120	S124I	124	Missense	distal	4	no	2.017	1.999	PhosphoSitePlus	TCGA;ICGC;COSMIC	1.526	Down-regulation
TK_Src_SrcB_LYN_Y	P35354	PTGS2	P07948	LYN	Y120	P113L	113	Missense	distal	-7	no	2.017	1.770	PhosphoSitePlus	TCGA;ICGC;COSMIC	1.526	Down-regulation
TK_Src_SrcB_LYN_Y	P35354	PTGS2	P07948	LYN	Y248	P249S	249	Missense	proximal	1	no	2.244	3.067	EPSD	TCGA;ICGC;COSMIC	1.526	Up-regulation
TK_Src_SrcB_LYN_Y	Q12972	PPP1R8	P07948	LYN	Y264	P268S	268	Missense	distal	4	no	4.182	3.998	EPSD	TCGA;ICGC;COSMIC	1.526	Down-regulation
AGC_RSK_RSKp90_RPS6KA3_ST	Q14934	NFATC4	P51812	RPS6KA3	S120	P114H	114	Missense	distal	-6	no	3.451	3.436	EPSD	TCGA	1.803	Down-regulation
AGC_RSK_RSKp90_RPS6KA3_ST	Q14934	NFATC4	P51812	RPS6KA3	S334	R332Q	332	Missense	proximal	-2	no	4.170	3.645	EPSD	TCGA;COSMIC	1.803	Down-regulation
AGC_RSK_RSKp90_RPS6KA3_ST	Q14934	NFATC4	P51812	RPS6KA3	S335	R332Q	332	Missense	distal	-3	no	3.504	0.998	EPSD	TCGA;COSMIC	1.803	Loss
AGC_RSK_RSKp90_RPS6KA3_ST	Q99683	MAP3K5	P51812	RPS6KA3	S82	R80Q	80	Missense	proximal	-2	no	2.365	1.840	EPSD	TCGA	1.803	Down-regulation
AGC_RSK_RSKp90_RPS6KA3_ST	Q99683	MAP3K5	P51812	RPS6KA3	S83	R80Q	80	Missense	distal	-3	no	4.412	1.906	PhosphoSitePlus;EPSD	TCGA	1.803	Down-regulation
AGC_RSK_RSKp90_RPS6KA3_ST	Q99683	MAP3K5	P51812	RPS6KA3	S613	S615C	615	Missense	proximal	2	no	3.751	3.650	EPSD	TCGA;COSMIC	1.803	Down-regulation
AGC_RSK_RSKp90_RPS6KA3_ST	Q99683	MAP3K5	P51812	RPS6KA3	S613	S607C	607	Missense	distal	-6	no	3.751	3.712	EPSD	TCGA;COSMIC	1.803	Down-regulation
AGC_RSK_RSKp90_RPS6KA3_ST	Q99683	MAP3K5	P51812	RPS6KA3	S613	S613N	613	Missense	central	0	yes	3.751	0.000	EPSD	TCGA;COSMIC	1.803	Loss
AGC_RSK_RSKp90_RPS6KA3_ST	Q99683	MAP3K5	P51812	RPS6KA3	S613	E618K	618	Missense	distal	5	no	3.751	3.727	EPSD	TCGA;ICGC;COSMIC	1.803	Down-regulation
AGC_RSK_RSKp90_RPS6KA3_ST	Q99683	MAP3K5	P51812	RPS6KA3	S613	R620I	620	Missense	distal	7	no	3.751	3.801	EPSD	TCGA;ICGC;COSMIC	1.803	Up-regulation
AGC_RSK_RSKp90_RPS6KA3_ST	Q99683	MAP3K5	P51812	RPS6KA3	S613	V609F	609	Missense	distal	-4	no	3.751	3.731	EPSD	TCGA;ICGC;COSMIC	1.803	Down-regulation
AGC_RSK_RSKp90_RPS6KA3_ST	Q99683	MAP3K5	P51812	RPS6KA3	S719	I726T	726	Missense	distal	7	no	2.810	2.818	EPSD	TCGA;ICGC;COSMIC	1.803	Up-regulation
AGC_RSK_RSKp90_RPS6KA3_ST	Q99683	MAP3K5	P51812	RPS6KA3	S719	L722P	722	Missense	distal	3	no	2.810	2.806	EPSD	TCGA;ICGC;COSMIC	1.803	Down-regulation
AGC_RSK_RSKp90_RPS6KA3_ST	Q99683	MAP3K5	P51812	RPS6KA3	S966	S966F	966	Missense	central	0	yes	4.046	0.000	EPSD	TCGA;COSMIC;CCLE	1.803	Loss
AGC_RSK_RSKp90_RPS6KA3_ST	Q99683	MAP3K5	P51812	RPS6KA3	S966	P968L	968	Missense	proximal	2	no	4.046	4.010	EPSD	TCGA;COSMIC	1.803	Down-regulation
AGC_RSK_RSKp90_RPS6KA3_ST	Q99683	MAP3K5	P51812	RPS6KA3	S984	E981K	981	Missense	distal	-3	no	1.558	2.032	EPSD	TCGA;COSMIC	1.803	Gain
AGC_RSK_RSKp90_RPS6KA3_ST	Q99683	MAP3K5	P51812	RPS6KA3	T1059	V1066M	1066	Missense	distal	7	no	2.286	2.268	EPSD	TCGA;COSMIC	1.803	Down-regulation
AGC_RSK_RSKp90_RPS6KA3_ST	Q99683	MAP3K5	P51812	RPS6KA3	T1059	T1059M	1059	Missense	central	0	yes	2.286	0.000	EPSD	TCGA;COSMIC	1.803	Loss
AGC_RSK_RSKp90_RPS6KA3_ST	Q99683	MAP3K5	P51812	RPS6KA3	S1072	V1066M	1066	Missense	distal	-6	no	2.149	2.171	EPSD	TCGA;COSMIC	1.803	Up-regulation
AGC_RSK_RSKp90_RPS6KA3_ST	Q99683	MAP3K5	P51812	RPS6KA3	S1072	E1078K	1078	Missense	distal	6	no	2.149	2.163	EPSD	TCGA;ICGC;COSMIC	1.803	Up-regulation
AGC_RSK_RSKp90_RPS6KA3_ST	Q99683	MAP3K5	P51812	RPS6KA3	S1072	S1072F	1072	Missense	central	0	yes	2.149	0.000	EPSD	TCGA;COSMIC	1.803	Loss
AGC_RSK_RSKp90_RPS6KA3_ST	Q99683	MAP3K5	P51812	RPS6KA3	S1072	L1073I	1073	Missense	proximal	1	no	2.149	2.140	EPSD	TCGA;COSMIC	1.803	Down-regulation
AGC_RSK_RSKp90_RPS6KA3_ST	Q92934	BAD	P51812	RPS6KA3	S74	S71I	71	Missense	distal	-3	no	1.804	1.345	EPSD	TCGA;ICGC;COSMIC	1.803	Loss
AGC_RSK_RSKp90_RPS6KA3_ST	Q92934	BAD	P51812	RPS6KA3	S75	S71I	71	Missense	distal	-4	no	4.372	4.281	PhosphoSitePlus;EPSD	TCGA;ICGC;COSMIC	1.803	Down-regulation
AGC_RSK_RSKp90_RPS6KA3_ST	Q92934	BAD	P51812	RPS6KA3	S97	A100T	100	Missense	distal	3	no	3.885	3.889	EPSD	TCGA;ICGC;COSMIC	1.803	Up-regulation
AGC_RSK_RSKp90_RPS6KA3_ST	Q92934	BAD	P51812	RPS6KA3	S99	A100T	100	Missense	proximal	1	no	4.010	4.061	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	1.803	Up-regulation
AGC_RSK_RSKp90_RPS6KA3_ST	Q92934	BAD	P51812	RPS6KA3	S118	M117I	117	Missense	proximal	-1	no	4.319	4.312	EPSD	TCGA;ICGC;COSMIC	1.803	Down-regulation
AGC_RSK_RSKp90_RPS6KA3_ST	Q92934	BAD	P51812	RPS6KA3	S134	R131H	131	Missense	distal	-3	no	3.650	1.112	EPSD	TCGA;ICGC;COSMIC	1.803	Loss
AGC_RSK_RSKp90_RPS6KA3_ST	Q92934	BAD	P51812	RPS6KA3	S134	G136D	136	Missense	proximal	2	no	3.650	3.633	EPSD	TCGA;ICGC;COSMIC	1.803	Down-regulation
AGC_RSK_RSKp90_RPS6KA3_ST	Q92934	BAD	P51812	RPS6KA3	S134	S134I	134	Missense	central	0	yes	3.650	0.000	EPSD	TCGA	1.803	Loss
AGC_RSK_RSKp90_RPS6KA3_ST	Q92934	BAD	P51812	RPS6KA3	S164	G162V	162	Missense	proximal	-2	no	3.626	3.536	EPSD	TCGA;ICGC;COSMIC	1.803	Down-regulation
AGC_RSK_RSKp90_RPS6KA3_ST	Q92934	BAD	P51812	RPS6KA3	S164	S164F	164	Missense	central	0	yes	3.626	0.000	EPSD	TCGA;ICGC;COSMIC;GDSC;CCLE	1.803	Loss
AGC_RSK_RSKp90_RPS6KA3_ST	Q92934	BAD	P51812	RPS6KA3	S164	S167P	167	Missense	distal	3	no	3.626	3.631	EPSD	TCGA;COSMIC	1.803	Up-regulation
AGC_RSK_RSKp90_RPS6KA3_ST	Q92934	BAD	P51812	RPS6KA3	S164	S163N	163	Missense	proximal	-1	no	3.626	3.598	EPSD	TCGA;ICGC;COSMIC	1.803	Down-regulation
AGC_RSK_RSKp90_RPS6KA3_ST	Q92934	BAD	P51812	RPS6KA3	S164	G162E	162	Missense	proximal	-2	no	3.626	3.628	EPSD	TCGA;ICGC	1.803	Up-regulation
AGC_RSK_RSKp90_RPS6KA3_ST	Q8IX03	WWC1	P51812	RPS6KA3	S33	R38W	38	Missense	distal	5	no	3.708	3.799	EPSD	TCGA;ICGC;COSMIC	1.803	Up-regulation
AGC_RSK_RSKp90_RPS6KA3_ST	Q8IX03	WWC1	P51812	RPS6KA3	S255	H256Y	256	Missense	proximal	1	no	1.978	1.989	EPSD	TCGA;ICGC;COSMIC	1.803	Up-regulation
AGC_RSK_RSKp90_RPS6KA3_ST	Q8IX03	WWC1	P51812	RPS6KA3	S255	S257L	257	Missense	proximal	2	no	1.978	1.871	EPSD	TCGA;ICGC;COSMIC	1.803	Down-regulation
AGC_RSK_RSKp90_RPS6KA3_ST	Q8IX03	WWC1	P51812	RPS6KA3	S268	S265C	265	Missense	distal	-3	no	1.826	1.223	EPSD	TCGA;ICGC;COSMIC	1.803	Loss
AGC_RSK_RSKp90_RPS6KA3_ST	Q8IX03	WWC1	P51812	RPS6KA3	S268	S269L	269	Missense	proximal	1	no	1.826	1.885	EPSD	TCGA;ICGC;COSMIC	1.803	Up-regulation
AGC_RSK_RSKp90_RPS6KA3_ST	Q8IX03	WWC1	P51812	RPS6KA3	S270	S265C	265	Missense	distal	-5	no	1.810	1.726	EPSD	TCGA;ICGC;COSMIC	1.803	Loss
AGC_RSK_RSKp90_RPS6KA3_ST	Q8IX03	WWC1	P51812	RPS6KA3	S270	S269L	269	Missense	proximal	-1	no	1.810	1.768	EPSD	TCGA;ICGC;COSMIC	1.803	Loss
AGC_RSK_RSKp90_RPS6KA3_ST	Q8IX03	WWC1	P51812	RPS6KA3	S441	R446Q	446	Missense	distal	5	no	1.947	2.014	EPSD	TCGA;ICGC;COSMIC	1.803	Up-regulation
AGC_RSK_RSKp90_RPS6KA3_ST	Q8IX03	WWC1	P51812	RPS6KA3	S525	S525F	525	Missense	central	0	yes	4.098	0.000	EPSD	TCGA;ICGC;COSMIC	1.803	Loss
AGC_RSK_RSKp90_RPS6KA3_ST	Q8IX03	WWC1	P51812	RPS6KA3	S525	P528S	528	Missense	distal	3	no	4.098	4.093	EPSD	TCGA;ICGC;COSMIC	1.803	Down-regulation
AGC_RSK_RSKp90_RPS6KA3_ST	Q8IX03	WWC1	P51812	RPS6KA3	S525	S523F	523	Missense	proximal	-2	no	4.098	3.861	EPSD	TCGA;ICGC;COSMIC	1.803	Down-regulation
AGC_RSK_RSKp90_RPS6KA3_ST	Q8IX03	WWC1	P51812	RPS6KA3	S525	M531I	531	Missense	distal	6	no	4.098	4.091	EPSD	TCGA;ICGC;COSMIC	1.803	Down-regulation
AGC_RSK_RSKp90_RPS6KA3_ST	Q8IX03	WWC1	P51812	RPS6KA3	S533	R537C	537	Missense	distal	4	no	2.203	2.262	EPSD	TCGA;ICGC;COSMIC	1.803	Up-regulation
AGC_RSK_RSKp90_RPS6KA3_ST	Q8IX03	WWC1	P51812	RPS6KA3	S533	P528S	528	Missense	distal	-5	no	2.203	2.210	EPSD	TCGA;ICGC;COSMIC	1.803	Up-regulation
AGC_RSK_RSKp90_RPS6KA3_ST	Q8IX03	WWC1	P51812	RPS6KA3	S533	L540F	540	Missense	distal	7	no	2.203	2.215	EPSD	TCGA;ICGC;COSMIC	1.803	Up-regulation
AGC_RSK_RSKp90_RPS6KA3_ST	Q8IX03	WWC1	P51812	RPS6KA3	S533	P536S	536	Missense	distal	3	no	2.203	2.198	EPSD	TCGA;ICGC;COSMIC	1.803	Down-regulation
AGC_RSK_RSKp90_RPS6KA3_ST	Q8IX03	WWC1	P51812	RPS6KA3	S533	S533F	533	Missense	central	0	yes	2.203	0.000	EPSD	TCGA;ICGC;COSMIC	1.803	Loss
AGC_RSK_RSKp90_RPS6KA3_ST	Q8IX03	WWC1	P51812	RPS6KA3	S533	M531I	531	Missense	proximal	-2	no	2.203	2.163	EPSD	TCGA;ICGC;COSMIC	1.803	Down-regulation
AGC_RSK_RSKp90_RPS6KA3_ST	Q8IX03	WWC1	P51812	RPS6KA3	S539	R537C	537	Missense	proximal	-2	no	2.227	1.646	EPSD	TCGA;ICGC;COSMIC	1.803	Loss
AGC_RSK_RSKp90_RPS6KA3_ST	Q8IX03	WWC1	P51812	RPS6KA3	S539	L540F	540	Missense	proximal	1	no	2.227	2.252	EPSD	TCGA;ICGC;COSMIC	1.803	Up-regulation
AGC_RSK_RSKp90_RPS6KA3_ST	Q8IX03	WWC1	P51812	RPS6KA3	S539	P536S	536	Missense	distal	-3	no	2.227	2.334	EPSD	TCGA;ICGC;COSMIC	1.803	Up-regulation
AGC_RSK_RSKp90_RPS6KA3_ST	Q8IX03	WWC1	P51812	RPS6KA3	S539	S533F	533	Missense	distal	-6	no	2.227	2.171	EPSD	TCGA;ICGC;COSMIC	1.803	Down-regulation
AGC_RSK_RSKp90_RPS6KA3_ST	Q8IX03	WWC1	P51812	RPS6KA3	S542	P549L	549	Missense	distal	7	no	2.417	2.436	EPSD	TCGA;ICGC;COSMIC	1.803	Up-regulation
AGC_RSK_RSKp90_RPS6KA3_ST	Q8IX03	WWC1	P51812	RPS6KA3	S542	R537C	537	Missense	distal	-5	no	2.417	2.016	EPSD	TCGA;ICGC;COSMIC	1.803	Down-regulation
AGC_RSK_RSKp90_RPS6KA3_ST	Q8IX03	WWC1	P51812	RPS6KA3	S542	L540F	540	Missense	proximal	-2	no	2.417	2.271	EPSD	TCGA;ICGC;COSMIC	1.803	Down-regulation
AGC_RSK_RSKp90_RPS6KA3_ST	Q8IX03	WWC1	P51812	RPS6KA3	S542	S548F	548	Missense	distal	6	no	2.417	2.349	EPSD	TCGA;ICGC;COSMIC	1.803	Down-regulation
AGC_RSK_RSKp90_RPS6KA3_ST	Q8IX03	WWC1	P51812	RPS6KA3	S542	P536S	536	Missense	distal	-6	no	2.417	2.434	EPSD	TCGA;ICGC;COSMIC	1.803	Up-regulation
AGC_RSK_RSKp90_RPS6KA3_ST	Q8IX03	WWC1	P51812	RPS6KA3	S848	E845K	845	Missense	distal	-3	no	1.687	2.161	EPSD	TCGA;ICGC;COSMIC	1.803	Gain
AGC_RSK_RSKp90_RPS6KA3_ST	Q8IX03	WWC1	P51812	RPS6KA3	T912	S914F	914	Missense	proximal	2	no	1.905	1.773	EPSD	TCGA;ICGC;COSMIC	1.803	Loss
AGC_RSK_RSKp90_RPS6KA3_ST	Q8IX03	WWC1	P51812	RPS6KA3	T912	P913L	913	Missense	proximal	1	no	1.905	1.925	EPSD	TCGA	1.803	Up-regulation
AGC_RSK_RSKp90_RPS6KA3_ST	Q8IX03	WWC1	P51812	RPS6KA3	S922	R926C	926	Missense	distal	4	no	1.866	1.924	EPSD	TCGA;ICGC;COSMIC	1.803	Up-regulation
AGC_RSK_RSKp90_RPS6KA3_ST	Q8IX03	WWC1	P51812	RPS6KA3	S922	R920L	920	Missense	proximal	-2	no	1.866	1.359	EPSD	TCGA;ICGC;COSMIC	1.803	Loss
AGC_RSK_RSKp90_RPS6KA3_ST	Q8IX03	WWC1	P51812	RPS6KA3	T923	R926C	926	Missense	distal	3	no	1.879	1.887	EPSD	TCGA;ICGC;COSMIC	1.803	Up-regulation
AGC_RSK_RSKp90_RPS6KA3_ST	Q8IX03	WWC1	P51812	RPS6KA3	T923	R920L	920	Missense	distal	-3	no	1.879	-0.352	EPSD	TCGA;ICGC;COSMIC	1.803	Loss
AGC_RSK_RSKp90_RPS6KA3_ST	Q8IX03	WWC1	P51812	RPS6KA3	T923	F930S	930	Missense	distal	7	no	1.879	1.822	EPSD	TCGA;ICGC;COSMIC	1.803	Down-regulation
AGC_RSK_RSKp90_RPS6KA3_ST	Q8IX03	WWC1	P51812	RPS6KA3	T929	R926C	926	Missense	distal	-3	no	2.595	-0.016	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	1.803	Loss
AGC_RSK_RSKp90_RPS6KA3_ST	Q8IX03	WWC1	P51812	RPS6KA3	T929	S931F	931	Missense	proximal	2	no	2.595	2.463	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	1.803	Down-regulation
AGC_RSK_RSKp90_RPS6KA3_ST	Q8IX03	WWC1	P51812	RPS6KA3	T929	F930S	930	Missense	proximal	1	no	2.595	2.511	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	1.803	Down-regulation
AGC_RSK_RSKp90_RPS6KA3_ST	Q8IX03	WWC1	P51812	RPS6KA3	S931	R926C	926	Missense	distal	-5	no	1.905	1.504	EPSD	TCGA;ICGC;COSMIC	1.803	Loss
AGC_RSK_RSKp90_RPS6KA3_ST	Q8IX03	WWC1	P51812	RPS6KA3	S931	Q937K	937	Missense	distal	6	no	1.905	1.917	EPSD	TCGA;ICGC;COSMIC	1.803	Up-regulation
AGC_RSK_RSKp90_RPS6KA3_ST	Q8IX03	WWC1	P51812	RPS6KA3	S931	S931F	931	Missense	central	0	yes	1.905	0.000	EPSD	TCGA;ICGC;COSMIC	1.803	Loss
AGC_RSK_RSKp90_RPS6KA3_ST	Q8IX03	WWC1	P51812	RPS6KA3	S931	F930S	930	Missense	proximal	-1	no	1.905	1.965	EPSD	TCGA;ICGC;COSMIC	1.803	Up-regulation
AGC_RSK_RSKp90_RPS6KA3_ST	Q8IX03	WWC1	P51812	RPS6KA3	S947	R941W	941	Missense	distal	-6	no	3.802	3.722	PhosphoSitePlus;EPSD	TCGA;ICGC;COSMIC	1.803	Down-regulation
AGC_RSK_RSKp90_RPS6KA3_ST	Q8IX03	WWC1	P51812	RPS6KA3	S953	R960Q	960	Missense	distal	7	no	1.896	1.933	EPSD	TCGA;ICGC;COSMIC	1.803	Up-regulation
AGC_RSK_RSKp90_RPS6KA3_ST	Q8IX03	WWC1	P51812	RPS6KA3	S974	S967N	967	Missense	distal	-7	no	2.314	2.327	EPSD	TCGA;ICGC;COSMIC	1.803	Up-regulation
AGC_RSK_RSKp90_RPS6KA3_ST	Q8IX03	WWC1	P51812	RPS6KA3	S974	V968I	968	Missense	distal	-6	no	2.314	2.329	EPSD	TCGA;ICGC;COSMIC	1.803	Up-regulation
AGC_RSK_RSKp90_RPS6KA3_ST	Q8IX03	WWC1	P51812	RPS6KA3	S974	R972Q	972	Missense	proximal	-2	no	2.314	1.789	EPSD	TCGA;ICGC;COSMIC;GDSC	1.803	Loss
AGC_RSK_RSKp90_RPS6KA3_ST	Q8IX03	WWC1	P51812	RPS6KA3	S975	V968I	968	Missense	distal	-7	no	3.999	3.995	EPSD	TCGA;ICGC;COSMIC	1.803	Down-regulation
AGC_RSK_RSKp90_RPS6KA3_ST	Q8IX03	WWC1	P51812	RPS6KA3	S975	R972Q	972	Missense	distal	-3	no	3.999	1.493	EPSD	TCGA;ICGC;COSMIC;GDSC	1.803	Loss
AGC_RSK_RSKp90_RPS6KA3_ST	Q8IX03	WWC1	P51812	RPS6KA3	S978	R972Q	972	Missense	distal	-6	no	1.965	1.898	EPSD	TCGA;ICGC;COSMIC;GDSC	1.803	Down-regulation
AGC_RSK_RSKp90_RPS6KA3_ST	Q8IX03	WWC1	P51812	RPS6KA3	S981	R986C	986	Missense	distal	5	no	1.710	1.812	EPSD	TCGA;ICGC;COSMIC	1.803	Gain
AGC_RSK_RSKp90_RPS6KA3_ST	P16220	CREB1	P51812	RPS6KA3	S98	S103A	103	Missense	distal	5	no	3.726	3.752	EPSD	TCGA;COSMIC	1.803	Up-regulation
AGC_RSK_RSKp90_RPS6KA3_ST	P16220	CREB1	P51812	RPS6KA3	S111	D116G	116	Missense	distal	5	no	1.833	1.837	EPSD	TCGA;COSMIC	1.803	Up-regulation
AGC_RSK_RSKp90_RPS6KA3_ST	P16220	CREB1	P51812	RPS6KA3	S111	Q112H	112	Missense	proximal	1	no	1.833	1.853	EPSD	TCGA;COSMIC	1.803	Up-regulation
AGC_RSK_RSKp90_RPS6KA3_ST	P16220	CREB1	P51812	RPS6KA3	S133	L128I	128	Missense	distal	-5	no	4.306	4.283	PhosphoSitePlus	TCGA;COSMIC	1.803	Down-regulation
AGC_RSK_RSKp90_RPS6KA3_ST	P49841	GSK3B	P51812	RPS6KA3	S35	G34S	34	Missense	proximal	-1	no	1.823	1.860	EPSD	TCGA;COSMIC	1.803	Up-regulation
AGC_RSK_RSKp90_RPS6KA3_ST	P49841	GSK3B	P51812	RPS6KA3	S147	R148G	148	Missense	proximal	1	no	3.392	3.491	EPSD	TCGA;ICGC;COSMIC	1.803	Up-regulation
AGC_RSK_RSKp90_RPS6KA3_ST	Q9H6Z4	RANBP3	P51812	RPS6KA3	S74	S72L	72	Missense	proximal	-2	no	1.889	1.798	EPSD	TCGA;ICGC;COSMIC	1.803	Loss
AGC_RSK_RSKp90_RPS6KA3_ST	Q9H6Z4	RANBP3	P51812	RPS6KA3	S74	A67V	67	Missense	distal	-7	no	1.889	1.903	EPSD	TCGA;ICGC;COSMIC	1.803	Up-regulation
AGC_RSK_RSKp90_RPS6KA3_ST	Q9H6Z4	RANBP3	P51812	RPS6KA3	S74	P77L	77	Missense	distal	3	no	1.889	1.892	EPSD	TCGA;COSMIC	1.803	Up-regulation
AGC_RSK_RSKp90_RPS6KA3_ST	Q9H6Z4	RANBP3	P51812	RPS6KA3	T124	E122G	122	Missense	proximal	-2	no	1.813	1.811	EPSD	TCGA;COSMIC	1.803	Down-regulation
AGC_RSK_RSKp90_RPS6KA3_ST	Q9H6Z4	RANBP3	P51812	RPS6KA3	T124	P117L	117	Missense	distal	-7	no	1.813	1.822	EPSD	TCGA;COSMIC	1.803	Up-regulation
AGC_RSK_RSKp90_RPS6KA3_ST	Q9H6Z4	RANBP3	P51812	RPS6KA3	T124	P131S	131	Missense	distal	7	no	1.813	1.786	EPSD	TCGA;COSMIC	1.803	Loss
AGC_RSK_RSKp90_RPS6KA3_ST	Q9H6Z4	RANBP3	P51812	RPS6KA3	S126	E122G	122	Missense	distal	-4	no	3.977	3.972	PhosphoSitePlus	TCGA;COSMIC	1.803	Down-regulation
AGC_RSK_RSKp90_RPS6KA3_ST	Q9H6Z4	RANBP3	P51812	RPS6KA3	S126	P131S	131	Missense	distal	5	no	3.977	3.937	PhosphoSitePlus	TCGA;COSMIC	1.803	Down-regulation
AGC_RSK_RSKp90_RPS6KA3_ST	Q9H6Z4	RANBP3	P51812	RPS6KA3	S221	D225E	225	Missense	distal	4	no	3.790	3.772	EPSD	TCGA;COSMIC;GDSC;CCLE	1.803	Down-regulation
AGC_RSK_RSKp90_RPS6KA3_ST	Q9H6Z4	RANBP3	P51812	RPS6KA3	S221	P220L	220	Missense	proximal	-1	no	3.790	3.774	EPSD	TCGA;ICGC;COSMIC	1.803	Down-regulation
AGC_RSK_RSKp90_RPS6KA3_ST	Q9H6Z4	RANBP3	P51812	RPS6KA3	S240	E245Q	245	Missense	distal	5	no	2.005	1.996	EPSD	TCGA;ICGC;COSMIC	1.803	Down-regulation
AGC_RSK_RSKp90_RPS6KA3_ST	Q9H6Z4	RANBP3	P51812	RPS6KA3	S333	E339K	339	Missense	distal	6	no	3.229	3.243	EPSD	TCGA;COSMIC	1.803	Up-regulation
AGC_RSK_RSKp90_RPS6KA3_ST	P07101	TH	P51812	RPS6KA3	S19	A23T	23	Missense	distal	4	no	3.611	3.661	EPSD	TCGA;ICGC;COSMIC	1.803	Up-regulation
AGC_RSK_RSKp90_RPS6KA3_ST	P07101	TH	P51812	RPS6KA3	S19	R15H	15	Missense	distal	-4	no	3.611	3.423	EPSD	TCGA;ICGC;COSMIC;GDSC	1.803	Down-regulation
AGC_RSK_RSKp90_RPS6KA3_ST	P07101	TH	P51812	RPS6KA3	S71	R64W	64	Missense	distal	-7	no	4.398	4.423	EPSD;PhosphoSitePlus	TCGA;COSMIC	1.803	Up-regulation
AGC_RSK_RSKp90_RPS6KA3_ST	P07101	TH	P51812	RPS6KA3	S71	K78N	78	Missense	distal	7	no	4.398	4.409	EPSD;PhosphoSitePlus	TCGA;COSMIC	1.803	Up-regulation
AGC_RSK_RSKp90_RPS6KA3_ST	P19525	EIF2AK2	P51812	RPS6KA3	S181	S181F	181	Missense	central	0	yes	1.851	0.000	EPSD	TCGA;ICGC;COSMIC	1.803	Loss
AGC_RSK_RSKp90_RPS6KA3_ST	P19525	EIF2AK2	P51812	RPS6KA3	S242	N235I	235	Missense	distal	-7	no	2.402	2.406	EPSD	TCGA;ICGC;COSMIC	1.803	Up-regulation
AGC_RSK_RSKp90_RPS6KA3_ST	P19525	EIF2AK2	P51812	RPS6KA3	S242	P245L	245	Missense	distal	3	no	2.402	2.406	EPSD	TCGA;ICGC;COSMIC	1.803	Up-regulation
AGC_RSK_RSKp90_RPS6KA3_ST	P19525	EIF2AK2	P51812	RPS6KA3	T529	I532M	532	Missense	distal	3	no	2.234	2.232	EPSD	TCGA;ICGC;COSMIC	1.803	Down-regulation
AGC_RSK_RSKp90_RPS6KA3_ST	P19525	EIF2AK2	P51812	RPS6KA3	T529	L536F	536	Missense	distal	7	no	2.234	2.246	EPSD	TCGA;ICGC;COSMIC	1.803	Up-regulation
AGC_RSK_RSKp90_RPS6KA3_ST	P19525	EIF2AK2	P51812	RPS6KA3	T529	E531K	531	Missense	proximal	2	no	2.234	2.259	EPSD	TCGA;ICGC;COSMIC	1.803	Up-regulation
AGC_RSK_RSKp90_RPS6KA3_ST	P19525	EIF2AK2	P51812	RPS6KA3	S530	I532M	532	Missense	proximal	2	no	1.974	1.987	EPSD	TCGA;ICGC;COSMIC	1.803	Up-regulation
AGC_RSK_RSKp90_RPS6KA3_ST	P19525	EIF2AK2	P51812	RPS6KA3	S530	L536F	536	Missense	distal	6	no	1.974	1.958	EPSD	TCGA;ICGC;COSMIC	1.803	Down-regulation
AGC_RSK_RSKp90_RPS6KA3_ST	P19525	EIF2AK2	P51812	RPS6KA3	S530	E531K	531	Missense	proximal	1	no	1.974	1.950	EPSD	TCGA;ICGC;COSMIC	1.803	Down-regulation
AGC_RSK_RSKp90_RPS6KA3_ST	P19525	EIF2AK2	P51812	RPS6KA3	T537	I532M	532	Missense	distal	-5	no	1.788	1.811	EPSD	TCGA;ICGC;COSMIC	1.803	Gain
AGC_RSK_RSKp90_RPS6KA3_ST	P19525	EIF2AK2	P51812	RPS6KA3	T537	E531K	531	Missense	distal	-6	no	1.788	1.808	EPSD	TCGA;ICGC;COSMIC	1.803	Gain
AGC_RSK_RSKp90_RPS6KA3_ST	P03372	ESR1	P51812	RPS6KA3	S154	P152T	152	Missense	proximal	-2	no	3.503	3.422	EPSD	TCGA;ICGC;COSMIC	1.803	Down-regulation
AGC_RSK_RSKp90_RPS6KA3_ST	P03372	ESR1	P51812	RPS6KA3	S167	A166S	166	Missense	proximal	-1	no	4.193	4.212	PhosphoSitePlus	TCGA;ICGC;COSMIC	1.803	Up-regulation
AGC_RSK_RSKp90_RPS6KA3_ST	P03372	ESR1	P51812	RPS6KA3	S167	K171M	171	Missense	distal	4	no	4.193	4.214	PhosphoSitePlus	TCGA;ICGC;COSMIC	1.803	Up-regulation
AGC_RSK_RSKp90_RPS6KA3_ST	P03372	ESR1	P51812	RPS6KA3	S236	K235N	235	Missense	proximal	-1	no	4.297	4.283	EPSD	TCGA;ICGC;COSMIC	1.803	Down-regulation
AGC_RSK_RSKp90_RPS6KA3_ST	P03372	ESR1	P51812	RPS6KA3	S236	A239S	239	Missense	distal	3	no	4.297	4.293	EPSD	TCGA;ICGC;COSMIC	1.803	Down-regulation
AGC_RSK_RSKp90_RPS6KA3_ST	P03372	ESR1	P51812	RPS6KA3	S236	R243H	243	Missense	distal	7	no	4.297	4.346	EPSD	TCGA;ICGC;COSMIC	1.803	Up-regulation
AGC_RSK_RSKp90_RPS6KA3_ST	P03372	ESR1	P51812	RPS6KA3	S236	R243C	243	Missense	distal	7	no	4.297	4.352	EPSD	TCGA;ICGC;COSMIC	1.803	Up-regulation
AGC_RSK_RSKp90_RPS6KA3_ST	P03372	ESR1	P51812	RPS6KA3	S236	C240Y	240	Missense	distal	4	no	4.297	4.302	EPSD	TCGA;ICGC;COSMIC	1.803	Up-regulation
AGC_RSK_RSKp90_RPS6KA3_ST	P03372	ESR1	P51812	RPS6KA3	S294	W292R	292	Missense	proximal	-2	no	1.374	1.933	EPSD	TCGA;ICGC;COSMIC	1.803	Gain
AGC_RSK_RSKp90_RPS6KA3_ST	P03372	ESR1	P51812	RPS6KA3	S305	I298M	298	Missense	distal	-7	no	1.964	1.960	EPSD	TCGA;ICGC;COSMIC	1.803	Down-regulation
AGC_RSK_RSKp90_RPS6KA3_ST	P03372	ESR1	P51812	RPS6KA3	S305	A307S	307	Missense	proximal	2	no	1.964	2.023	EPSD	TCGA;ICGC;COSMIC	1.803	Up-regulation
AGC_RSK_RSKp90_RPS6KA3_ST	P03372	ESR1	P51812	RPS6KA3	S305	T311M	311	Missense	distal	6	no	1.964	1.985	EPSD	TCGA;ICGC;COSMIC	1.803	Up-regulation
AGC_RSK_RSKp90_RPS6KA3_ST	P03372	ESR1	P51812	RPS6KA3	S554	R555C	555	Missense	proximal	1	no	1.730	1.830	EPSD	TCGA;ICGC;COSMIC	1.803	Gain
AGC_RSK_RSKp90_RPS6KA3_ST	P03372	ESR1	P51812	RPS6KA3	S554	R555H	555	Missense	proximal	1	no	1.730	1.822	EPSD	TCGA;ICGC;COSMIC;GDSC	1.803	Gain
AGC_RSK_RSKp90_RPS6KA3_ST	P62753	RPS6	P51812	RPS6KA3	T34	A33T	33	Missense	proximal	-1	no	2.055	2.026	EPSD	TCGA;ICGC;COSMIC	1.803	Down-regulation
AGC_RSK_RSKp90_RPS6KA3_ST	P62753	RPS6	P51812	RPS6KA3	T34	D39G	39	Missense	distal	5	no	2.055	2.058	EPSD	TCGA;ICGC;COSMIC	1.803	Up-regulation
AGC_RSK_RSKp90_RPS6KA3_ST	P62753	RPS6	P51812	RPS6KA3	T181	R178H	178	Missense	distal	-3	no	1.930	-0.608	EPSD	TCGA	1.803	Loss
AGC_RSK_RSKp90_RPS6KA3_ST	P62753	RPS6	P51812	RPS6KA3	T181	R183C	183	Missense	proximal	2	no	1.930	1.821	EPSD	TCGA;ICGC;COSMIC;GDSC;CCLE	1.803	Down-regulation
AGC_RSK_RSKp90_RPS6KA3_ST	P62753	RPS6	P51812	RPS6KA3	S235	K230N	230	Missense	distal	-5	no	4.089	4.056	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	1.803	Down-regulation
AGC_RSK_RSKp90_RPS6KA3_ST	P62753	RPS6	P51812	RPS6KA3	S235	S236C	236	Missense	proximal	1	no	4.089	4.149	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	1.803	Up-regulation
AGC_RSK_RSKp90_RPS6KA3_ST	P62753	RPS6	P51812	RPS6KA3	S235	R232H	232	Missense	distal	-3	no	4.089	1.551	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	1.803	Loss
AGC_RSK_RSKp90_RPS6KA3_ST	P62753	RPS6	P51812	RPS6KA3	S235	R233I	233	Missense	proximal	-2	no	4.089	3.545	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	1.803	Down-regulation
AGC_RSK_RSKp90_RPS6KA3_ST	P62753	RPS6	P51812	RPS6KA3	S235	R232C	232	Missense	distal	-3	no	4.089	1.479	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	1.803	Loss
AGC_RSK_RSKp90_RPS6KA3_ST	P62753	RPS6	P51812	RPS6KA3	S236	K230N	230	Missense	distal	-6	no	4.462	4.448	PhosphoSitePlus;EPSD	TCGA;ICGC;COSMIC	1.803	Down-regulation
AGC_RSK_RSKp90_RPS6KA3_ST	P62753	RPS6	P51812	RPS6KA3	S236	S236C	236	Missense	central	0	yes	4.462	0.000	PhosphoSitePlus;EPSD	TCGA;ICGC;COSMIC	1.803	Loss
AGC_RSK_RSKp90_RPS6KA3_ST	P62753	RPS6	P51812	RPS6KA3	S236	R232H	232	Missense	distal	-4	no	4.462	4.274	PhosphoSitePlus;EPSD	TCGA;ICGC;COSMIC	1.803	Down-regulation
AGC_RSK_RSKp90_RPS6KA3_ST	P62753	RPS6	P51812	RPS6KA3	S236	R233I	233	Missense	distal	-3	no	4.462	1.996	PhosphoSitePlus;EPSD	TCGA;ICGC;COSMIC	1.803	Down-regulation
AGC_RSK_RSKp90_RPS6KA3_ST	P62753	RPS6	P51812	RPS6KA3	S236	R232C	232	Missense	distal	-4	no	4.462	4.263	PhosphoSitePlus;EPSD	TCGA;ICGC;COSMIC	1.803	Down-regulation
AGC_RSK_RSKp90_RPS6KA3_ST	P62753	RPS6	P51812	RPS6KA3	S240	S236C	236	Missense	distal	-4	no	2.396	2.292	EPSD	TCGA;ICGC;COSMIC	1.803	Down-regulation
AGC_RSK_RSKp90_RPS6KA3_ST	P62753	RPS6	P51812	RPS6KA3	S240	R233I	233	Missense	distal	-7	no	2.396	2.422	EPSD	TCGA;ICGC;COSMIC	1.803	Up-regulation
AGC_RSK_RSKp90_RPS6KA3_ST	P62753	RPS6	P51812	RPS6KA3	T241	S236C	236	Missense	distal	-5	no	2.166	2.082	EPSD	TCGA;ICGC;COSMIC	1.803	Down-regulation
AGC_RSK_RSKp90_RPS6KA3_ST	P62753	RPS6	P51812	RPS6KA3	T241	Q248H	248	Missense	distal	7	no	2.166	2.178	EPSD	TCGA;ICGC;COSMIC	1.803	Up-regulation
AGC_RSK_RSKp90_RPS6KA3_ST	P62753	RPS6	P51812	RPS6KA3	S247	Q248H	248	Missense	proximal	1	no	1.829	1.850	EPSD	TCGA;ICGC;COSMIC	1.803	Up-regulation
AGC_RSK_RSKp90_RPS6KA3_ST	P67809	YBX1	P51812	RPS6KA3	S102	R101C	101	Missense	proximal	-1	no	1.917	1.844	PhosphoSitePlus	TCGA;ICGC;COSMIC	1.803	Down-regulation
AGC_RSK_RSKp90_RPS6KA3_ST	P67809	YBX1	P51812	RPS6KA3	S102	R97M	97	Missense	distal	-5	no	1.917	1.572	PhosphoSitePlus	TCGA;ICGC;COSMIC	1.803	Loss
AGC_RSK_RSKp90_RPS6KA3_ST	Q9BSI4	TINF2	P51812	RPS6KA3	S324	A323P	323	Missense	proximal	-1	no	3.280	3.273	EPSD	TCGA;ICGC;COSMIC	1.803	Down-regulation
AGC_RSK_RSKp90_RPS6KA3_ST	Q9BSI4	TINF2	P51812	RPS6KA3	S324	A322S	322	Missense	proximal	-2	no	3.280	3.318	EPSD	TCGA;ICGC	1.803	Up-regulation
AGC_RSK_RSKp90_RPS6KA3_ST	Q9BSI4	TINF2	P51812	RPS6KA3	S330	A323P	323	Missense	distal	-7	no	2.111	2.115	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	1.803	Up-regulation
AGC_RSK_RSKp90_RPS6KA3_ST	Q9NYV6	RRN3	P51812	RPS6KA3	S17	A14G	14	Missense	distal	-3	no	1.842	1.571	EPSD	TCGA;ICGC;COSMIC	1.803	Loss
AGC_RSK_RSKp90_RPS6KA3_ST	Q9NYV6	RRN3	P51812	RPS6KA3	S635	S640F	640	Missense	distal	5	no	3.682	3.781	EPSD	TCGA;COSMIC	1.803	Up-regulation
AGC_RSK_RSKp90_RPS6KA3_ST	Q9NYV6	RRN3	P51812	RPS6KA3	S635	P641S	641	Missense	distal	6	no	3.682	3.717	EPSD	TCGA;COSMIC	1.803	Up-regulation
AGC_RSK_RSKp90_RPS6KA3_ST	Q9NYV6	RRN3	P51812	RPS6KA3	S635	F631L	631	Missense	distal	-4	no	3.682	3.732	EPSD	TCGA;COSMIC	1.803	Up-regulation
AGC_RSK_RSKp90_RPS6KA3_ST	Q9NYV6	RRN3	P51812	RPS6KA3	S636	S640F	640	Missense	distal	4	no	1.793	1.874	EPSD	TCGA;COSMIC	1.803	Gain
AGC_RSK_RSKp90_RPS6KA3_ST	Q9NYV6	RRN3	P51812	RPS6KA3	S636	F631L	631	Missense	distal	-5	no	1.793	1.897	EPSD	TCGA;COSMIC	1.803	Gain
AGC_RSK_RSKp90_RPS6KA3_ST	Q9NYV6	RRN3	P51812	RPS6KA3	S637	S640F	640	Missense	distal	3	no	2.101	2.111	EPSD	TCGA;COSMIC	1.803	Up-regulation
AGC_RSK_RSKp90_RPS6KA3_ST	Q9NYV6	RRN3	P51812	RPS6KA3	S637	P641S	641	Missense	distal	4	no	2.101	2.062	EPSD	TCGA;COSMIC	1.803	Down-regulation
AGC_RSK_RSKp90_RPS6KA3_ST	Q9NYV6	RRN3	P51812	RPS6KA3	S637	F631L	631	Missense	distal	-6	no	2.101	2.122	EPSD	TCGA;COSMIC	1.803	Up-regulation
AGC_RSK_RSKp90_RPS6KA3_ST	P13796	LCP1	P51812	RPS6KA3	S5	A2V	2	Missense	distal	-3	no	2.014	1.301	PhosphoSitePlus	TCGA;ICGC	1.803	Loss
AGC_RSK_RSKp90_RPS6KA3_ST	P13796	LCP1	P51812	RPS6KA3	S5	S7P	7	Missense	proximal	2	no	2.014	1.943	PhosphoSitePlus	TCGA;ICGC;COSMIC	1.803	Down-regulation
AGC_RSK_RSKp90_RPS6KA3_ST	P13796	LCP1	P51812	RPS6KA3	S5	M11I	11	Missense	distal	6	no	2.014	2.007	PhosphoSitePlus	TCGA;ICGC;COSMIC	1.803	Down-regulation
AGC_RSK_RSKp90_RPS6KA3_ST	P13796	LCP1	P51812	RPS6KA3	T54	V50L	50	Missense	distal	-4	no	2.019	2.049	EPSD	TCGA;ICGC;COSMIC	1.803	Up-regulation
AGC_RSK_RSKp90_RPS6KA3_ST	P13796	LCP1	P51812	RPS6KA3	T54	R51Q	51	Missense	distal	-3	no	2.019	-0.487	EPSD	TCGA;ICGC;COSMIC	1.803	Loss
AGC_RSK_RSKp90_RPS6KA3_ST	P13796	LCP1	P51812	RPS6KA3	T54	M58T	58	Missense	distal	4	no	2.019	2.047	EPSD	TCGA;ICGC;COSMIC	1.803	Up-regulation
AGC_RSK_RSKp90_RPS6KA3_ST	P13796	LCP1	P51812	RPS6KA3	S296	K294R	294	Missense	proximal	-2	no	1.386	1.805	EPSD	TCGA;ICGC;COSMIC	1.803	Gain
AGC_RSK_RSKp90_RPS6KA3_ST	P13796	LCP1	P51812	RPS6KA3	T503	Y502S	502	Missense	proximal	-1	no	2.317	2.362	EPSD	TCGA;COSMIC	1.803	Up-regulation
AGC_RSK_RSKp90_RPS6KA3_ST	P13796	LCP1	P51812	RPS6KA3	T503	E508K	508	Missense	distal	5	no	2.317	2.292	EPSD	TCGA	1.803	Down-regulation
AGC_RSK_RSKp90_RPS6KA3_ST	P13796	LCP1	P51812	RPS6KA3	S537	P544L	544	Missense	distal	7	no	1.846	1.865	EPSD	TCGA;COSMIC	1.803	Up-regulation
AGC_RSK_RSKp90_RPS6KA3_ST	P13796	LCP1	P51812	RPS6KA3	S539	P544L	544	Missense	distal	5	no	2.264	2.303	EPSD	TCGA;COSMIC	1.803	Up-regulation
AGC_RSK_RSKp90_RPS6KA3_ST	P19105	MYL12A	P51812	RPS6KA3	S19	R13C	13	Missense	distal	-6	no	3.466	3.380	PhosphoSitePlus	TCGA;ICGC;COSMIC	1.803	Down-regulation
AGC_RSK_RSKp90_RPS6KA3_ST	Q9UL17	TBX21	P51812	RPS6KA3	S394	A389P	389	Missense	distal	-5	no	3.886	3.875	EPSD	TCGA;ICGC;COSMIC;CCLE	1.803	Down-regulation
AGC_RSK_RSKp90_RPS6KA3_ST	Q9UL17	TBX21	P51812	RPS6KA3	S403	M404I	404	Missense	proximal	1	no	3.868	3.882	EPSD	TCGA;ICGC;COSMIC	1.803	Up-regulation
AGC_RSK_RSKp90_RPS6KA3_ST	Q9UL17	TBX21	P51812	RPS6KA3	S503	K498N	498	Missense	distal	-5	no	4.048	4.015	PhosphoSitePlus;EPSD	TCGA;ICGC;COSMIC	1.803	Down-regulation
AGC_RSK_RSKp90_RPS6KA3_ST	Q9UL17	TBX21	P51812	RPS6KA3	S503	P504S	504	Missense	proximal	1	no	4.048	4.009	PhosphoSitePlus;EPSD	TCGA;ICGC;COSMIC	1.803	Down-regulation
AGC_RSK_RSKp90_RPS6KA3_ST	Q9UL17	TBX21	P51812	RPS6KA3	S503	P504L	504	Missense	proximal	1	no	4.048	4.068	PhosphoSitePlus;EPSD	TCGA;ICGC;COSMIC	1.803	Up-regulation
AGC_RSK_RSKp90_RPS6KA3_ST	Q9UL17	TBX21	P51812	RPS6KA3	S503	R501H	501	Missense	proximal	-2	no	4.048	3.492	PhosphoSitePlus;EPSD	TCGA;ICGC;COSMIC	1.803	Down-regulation
AGC_RSK_RSKp90_RPS6KA3_ST	Q9UL17	TBX21	P51812	RPS6KA3	S507	P504S	504	Missense	distal	-3	no	1.879	1.986	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	1.803	Up-regulation
AGC_RSK_RSKp90_RPS6KA3_ST	Q9UL17	TBX21	P51812	RPS6KA3	S507	P504L	504	Missense	distal	-3	no	1.879	1.763	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	1.803	Loss
AGC_RSK_RSKp90_RPS6KA3_ST	Q9UL17	TBX21	P51812	RPS6KA3	S507	R501H	501	Missense	distal	-6	no	1.879	1.799	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	1.803	Loss
AGC_RSK_RSKp90_RPS6KA3_ST	P53355	DAPK1	P51812	RPS6KA3	S57	R58H	58	Missense	proximal	1	no	3.715	3.807	EPSD	TCGA;ICGC;COSMIC	1.803	Up-regulation
AGC_RSK_RSKp90_RPS6KA3_ST	P53355	DAPK1	P51812	RPS6KA3	S57	R54W	54	Missense	distal	-3	no	3.715	1.173	EPSD	TCGA;ICGC	1.803	Loss
AGC_RSK_RSKp90_RPS6KA3_ST	P53355	DAPK1	P51812	RPS6KA3	S57	R54Q	54	Missense	distal	-3	no	3.715	1.209	EPSD	TCGA;ICGC;COSMIC	1.803	Loss
AGC_RSK_RSKp90_RPS6KA3_ST	P53355	DAPK1	P51812	RPS6KA3	S57	S51F	51	Missense	distal	-6	no	3.715	3.659	EPSD	TCGA	1.803	Down-regulation
AGC_RSK_RSKp90_RPS6KA3_ST	P53355	DAPK1	P51812	RPS6KA3	S57	R53Q	53	Missense	distal	-4	no	3.715	3.549	EPSD	TCGA;ICGC	1.803	Down-regulation
AGC_RSK_RSKp90_RPS6KA3_ST	P53355	DAPK1	P51812	RPS6KA3	S57	R58C	58	Missense	proximal	1	no	3.715	3.815	EPSD	TCGA;COSMIC	1.803	Up-regulation
AGC_RSK_RSKp90_RPS6KA3_ST	P53355	DAPK1	P51812	RPS6KA3	S289	A290T	290	Missense	proximal	1	no	4.083	4.134	PhosphoSitePlus	TCGA;ICGC;COSMIC	1.803	Up-regulation
AGC_RSK_RSKp90_RPS6KA3_ST	P53355	DAPK1	P51812	RPS6KA3	S313	R310C	310	Missense	distal	-3	no	3.844	1.233	EPSD	TCGA;ICGC;COSMIC	1.803	Loss
AGC_RSK_RSKp90_RPS6KA3_ST	P53355	DAPK1	P51812	RPS6KA3	S313	R317I	317	Missense	distal	4	no	3.844	3.899	EPSD	TCGA;ICGC;COSMIC	1.803	Up-regulation
AGC_RSK_RSKp90_RPS6KA3_ST	P53355	DAPK1	P51812	RPS6KA3	S321	M328V	328	Missense	distal	7	no	1.807	1.825	EPSD	TCGA;ICGC;COSMIC	1.803	Up-regulation
AGC_RSK_RSKp90_RPS6KA3_ST	P53355	DAPK1	P51812	RPS6KA3	S321	R317I	317	Missense	distal	-4	no	1.807	1.620	EPSD	TCGA;ICGC;COSMIC	1.803	Loss
AGC_RSK_RSKp90_RPS6KA3_ST	P53355	DAPK1	P51812	RPS6KA3	S329	M328V	328	Missense	proximal	-1	no	1.804	1.784	EPSD	TCGA;ICGC;COSMIC	1.803	Loss
AGC_RSK_RSKp90_RPS6KA3_ST	P53355	DAPK1	P51812	RPS6KA3	S724	P721S	721	Missense	distal	-3	no	2.514	2.621	EPSD	TCGA;ICGC;COSMIC	1.803	Up-regulation
AGC_RSK_RSKp90_RPS6KA3_ST	P53355	DAPK1	P51812	RPS6KA3	S724	R719C	719	Missense	distal	-5	no	2.514	2.113	EPSD	TCGA;ICGC;GDSC;CCLE	1.803	Down-regulation
AGC_RSK_RSKp90_RPS6KA3_ST	P53355	DAPK1	P51812	RPS6KA3	S725	P721S	721	Missense	distal	-4	no	3.723	3.779	EPSD	TCGA;ICGC;COSMIC	1.803	Up-regulation
AGC_RSK_RSKp90_RPS6KA3_ST	P53355	DAPK1	P51812	RPS6KA3	S725	R719C	719	Missense	distal	-6	no	3.723	3.636	EPSD	TCGA;ICGC;GDSC;CCLE	1.803	Down-regulation
AGC_RSK_RSKp90_RPS6KA3_ST	P53355	DAPK1	P51812	RPS6KA3	S728	P733H	733	Missense	distal	5	no	1.910	1.931	EPSD	TCGA	1.803	Up-regulation
AGC_RSK_RSKp90_RPS6KA3_ST	P53355	DAPK1	P51812	RPS6KA3	S728	P735L	735	Missense	distal	7	no	1.910	1.929	EPSD	TCGA;ICGC;COSMIC	1.803	Up-regulation
AGC_RSK_RSKp90_RPS6KA3_ST	P53355	DAPK1	P51812	RPS6KA3	S728	P721S	721	Missense	distal	-7	no	1.910	1.900	EPSD	TCGA;ICGC;COSMIC	1.803	Down-regulation
AGC_RSK_RSKp90_RPS6KA3_ST	P53355	DAPK1	P51812	RPS6KA3	S762	M763T	763	Missense	proximal	1	no	3.212	3.246	EPSD	TCGA;ICGC;COSMIC	1.803	Up-regulation
AGC_RSK_RSKp90_RPS6KA3_ST	P53355	DAPK1	P51812	RPS6KA3	S762	V756M	756	Missense	distal	-6	no	3.212	3.233	EPSD	TCGA;ICGC	1.803	Up-regulation
AGC_RSK_RSKp90_RPS6KA3_ST	P53355	DAPK1	P51812	RPS6KA3	S762	F765L	765	Missense	distal	3	no	3.212	3.210	EPSD	TCGA;ICGC;COSMIC	1.803	Down-regulation
AGC_RSK_RSKp90_RPS6KA3_ST	Q16821	PPP1R3A	P51812	RPS6KA3	S46	S48C	48	Missense	proximal	2	no	4.523	4.423	PhosphoSitePlus;EPSD	TCGA;ICGC;COSMIC	1.803	Down-regulation
AGC_RSK_RSKp90_RPS6KA3_ST	Q16821	PPP1R3A	P51812	RPS6KA3	S46	R44Q	44	Missense	proximal	-2	no	4.523	3.998	PhosphoSitePlus;EPSD	TCGA;ICGC;COSMIC	1.803	Down-regulation
AGC_RSK_RSKp90_RPS6KA3_ST	Q16821	PPP1R3A	P51812	RPS6KA3	S46	E50K	50	Missense	distal	4	no	4.523	4.509	PhosphoSitePlus;EPSD	TCGA;ICGC;COSMIC	1.803	Down-regulation
AGC_RSK_RSKp90_RPS6KA3_ST	Q16821	PPP1R3A	P51812	RPS6KA3	S46	S42R	42	Missense	distal	-4	no	4.523	4.619	PhosphoSitePlus;EPSD	TCGA;ICGC;COSMIC	1.803	Up-regulation
AGC_RSK_RSKp90_RPS6KA3_ST	Q16821	PPP1R3A	P51812	RPS6KA3	S46	D47Y	47	Missense	proximal	1	no	4.523	4.528	PhosphoSitePlus;EPSD	TCGA;ICGC;COSMIC	1.803	Up-regulation
AGC_RSK_RSKp90_RPS6KA3_ST	Q16821	PPP1R3A	P51812	RPS6KA3	S46	D51Y	51	Missense	distal	5	no	4.523	4.532	PhosphoSitePlus;EPSD	TCGA;ICGC;COSMIC	1.803	Up-regulation
AGC_RSK_RSKp90_RPS6KA3_ST	Q16821	PPP1R3A	P51812	RPS6KA3	S46	P41T	41	Missense	distal	-5	no	4.523	4.483	PhosphoSitePlus;EPSD	TCGA;ICGC;COSMIC	1.803	Down-regulation
AGC_RSK_RSKp90_RPS6KA3_ST	Q16821	PPP1R3A	P51812	RPS6KA3	S46	D47H	47	Missense	proximal	1	no	4.523	4.516	PhosphoSitePlus;EPSD	TCGA;ICGC;COSMIC	1.803	Down-regulation
AGC_RSK_RSKp90_RPS6KA3_ST	Q16821	PPP1R3A	P51812	RPS6KA3	S46	S48F	48	Missense	proximal	2	no	4.523	4.392	PhosphoSitePlus;EPSD	TCGA;ICGC;COSMIC	1.803	Down-regulation
AGC_RSK_RSKp90_RPS6KA3_ST	Q16821	PPP1R3A	P51812	RPS6KA3	S46	D51H	51	Missense	distal	5	no	4.523	4.518	PhosphoSitePlus;EPSD	TCGA;ICGC;COSMIC	1.803	Down-regulation
AGC_RSK_RSKp90_RPS6KA3_ST	Q16821	PPP1R3A	P51812	RPS6KA3	S48	S48C	48	Missense	central	0	yes	1.929	0.000	EPSD	TCGA;ICGC;COSMIC	1.803	Loss
AGC_RSK_RSKp90_RPS6KA3_ST	Q16821	PPP1R3A	P51812	RPS6KA3	S48	R44Q	44	Missense	distal	-4	no	1.929	1.763	EPSD	TCGA;ICGC;COSMIC	1.803	Loss
AGC_RSK_RSKp90_RPS6KA3_ST	Q16821	PPP1R3A	P51812	RPS6KA3	S48	E50K	50	Missense	proximal	2	no	1.929	1.954	EPSD	TCGA;ICGC;COSMIC	1.803	Up-regulation
AGC_RSK_RSKp90_RPS6KA3_ST	Q16821	PPP1R3A	P51812	RPS6KA3	S48	S42R	42	Missense	distal	-6	no	1.929	1.977	EPSD	TCGA;ICGC;COSMIC	1.803	Up-regulation
AGC_RSK_RSKp90_RPS6KA3_ST	Q16821	PPP1R3A	P51812	RPS6KA3	S48	D47Y	47	Missense	proximal	-1	no	1.929	1.926	EPSD	TCGA;ICGC;COSMIC	1.803	Down-regulation
AGC_RSK_RSKp90_RPS6KA3_ST	Q16821	PPP1R3A	P51812	RPS6KA3	S48	D51Y	51	Missense	distal	3	no	1.929	1.930	EPSD	TCGA;ICGC;COSMIC	1.803	Up-regulation
AGC_RSK_RSKp90_RPS6KA3_ST	Q16821	PPP1R3A	P51812	RPS6KA3	S48	P41T	41	Missense	distal	-7	no	1.929	1.940	EPSD	TCGA;ICGC;COSMIC	1.803	Up-regulation
AGC_RSK_RSKp90_RPS6KA3_ST	Q16821	PPP1R3A	P51812	RPS6KA3	S48	D55Y	55	Missense	distal	7	no	1.929	1.933	EPSD	TCGA;ICGC;COSMIC	1.803	Up-regulation
AGC_RSK_RSKp90_RPS6KA3_ST	Q16821	PPP1R3A	P51812	RPS6KA3	S48	D47H	47	Missense	proximal	-1	no	1.929	1.932	EPSD	TCGA;ICGC;COSMIC	1.803	Up-regulation
AGC_RSK_RSKp90_RPS6KA3_ST	Q16821	PPP1R3A	P51812	RPS6KA3	S48	S48F	48	Missense	central	0	yes	1.929	0.000	EPSD	TCGA;ICGC;COSMIC	1.803	Loss
AGC_RSK_RSKp90_RPS6KA3_ST	Q16821	PPP1R3A	P51812	RPS6KA3	S49	S48C	48	Missense	proximal	-1	no	1.834	1.790	EPSD	TCGA;ICGC;COSMIC	1.803	Loss
AGC_RSK_RSKp90_RPS6KA3_ST	Q16821	PPP1R3A	P51812	RPS6KA3	S49	R44Q	44	Missense	distal	-5	no	1.834	1.472	EPSD	TCGA;ICGC;COSMIC	1.803	Loss
AGC_RSK_RSKp90_RPS6KA3_ST	Q16821	PPP1R3A	P51812	RPS6KA3	S49	E50K	50	Missense	proximal	1	no	1.834	1.811	EPSD	TCGA;ICGC;COSMIC	1.803	Down-regulation
AGC_RSK_RSKp90_RPS6KA3_ST	Q16821	PPP1R3A	P51812	RPS6KA3	S49	S42R	42	Missense	distal	-7	no	1.834	1.825	EPSD	TCGA;ICGC;COSMIC	1.803	Down-regulation
AGC_RSK_RSKp90_RPS6KA3_ST	Q16821	PPP1R3A	P51812	RPS6KA3	S49	D47Y	47	Missense	proximal	-2	no	1.834	1.840	EPSD	TCGA;ICGC;COSMIC	1.803	Up-regulation
AGC_RSK_RSKp90_RPS6KA3_ST	Q16821	PPP1R3A	P51812	RPS6KA3	S49	D51Y	51	Missense	proximal	2	no	1.834	1.833	EPSD	TCGA;ICGC;COSMIC	1.803	Down-regulation
AGC_RSK_RSKp90_RPS6KA3_ST	Q16821	PPP1R3A	P51812	RPS6KA3	S49	D55Y	55	Missense	distal	6	no	1.834	1.832	EPSD	TCGA;ICGC;COSMIC	1.803	Down-regulation
AGC_RSK_RSKp90_RPS6KA3_ST	Q16821	PPP1R3A	P51812	RPS6KA3	S49	D47H	47	Missense	proximal	-2	no	1.834	1.852	EPSD	TCGA;ICGC;COSMIC	1.803	Up-regulation
AGC_RSK_RSKp90_RPS6KA3_ST	Q16821	PPP1R3A	P51812	RPS6KA3	S49	S48F	48	Missense	proximal	-1	no	1.834	1.774	EPSD	TCGA;ICGC;COSMIC	1.803	Loss
AGC_RSK_RSKp90_RPS6KA3_ST	Q16821	PPP1R3A	P51812	RPS6KA3	S49	D51H	51	Missense	proximal	2	no	1.834	1.844	EPSD	TCGA;ICGC;COSMIC	1.803	Up-regulation
AGC_RSK_RSKp90_RPS6KA3_ST	Q16821	PPP1R3A	P51812	RPS6KA3	S65	S58F	58	Missense	distal	-7	no	4.168	4.193	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	1.803	Up-regulation
AGC_RSK_RSKp90_RPS6KA3_ST	Q16821	PPP1R3A	P51812	RPS6KA3	S65	S69F	69	Missense	distal	4	no	4.168	4.249	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	1.803	Up-regulation
AGC_RSK_RSKp90_RPS6KA3_ST	Q16821	PPP1R3A	P51812	RPS6KA3	S65	S59L	59	Missense	distal	-6	no	4.168	4.134	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	1.803	Down-regulation
AGC_RSK_RSKp90_RPS6KA3_ST	Q16821	PPP1R3A	P51812	RPS6KA3	S65	G71E	71	Missense	distal	6	no	4.168	4.174	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	1.803	Up-regulation
AGC_RSK_RSKp90_RPS6KA3_ST	Q16821	PPP1R3A	P51812	RPS6KA3	S65	R63I	63	Missense	proximal	-2	no	4.168	3.624	EPSD;PhosphoSitePlus	TCGA;ICGC	1.803	Down-regulation
AGC_RSK_RSKp90_RPS6KA3_ST	Q16821	PPP1R3A	P51812	RPS6KA3	S65	G60S	60	Missense	distal	-5	no	4.168	4.220	EPSD;PhosphoSitePlus	TCGA;ICGC	1.803	Up-regulation
AGC_RSK_RSKp90_RPS6KA3_ST	Q16821	PPP1R3A	P51812	RPS6KA3	S332	Q325K	325	Missense	distal	-7	no	3.566	3.561	EPSD	TCGA;ICGC;COSMIC	1.803	Down-regulation
AGC_RSK_RSKp90_RPS6KA3_ST	Q16821	PPP1R3A	P51812	RPS6KA3	S332	R336I	336	Missense	distal	4	no	3.566	3.622	EPSD	TCGA;ICGC;COSMIC	1.803	Up-regulation
AGC_RSK_RSKp90_RPS6KA3_ST	Q16821	PPP1R3A	P51812	RPS6KA3	S332	H326N	326	Missense	distal	-6	no	3.566	3.578	EPSD	TCGA;ICGC;COSMIC	1.803	Up-regulation
AGC_RSK_RSKp90_RPS6KA3_ST	Q16821	PPP1R3A	P51812	RPS6KA3	S332	D337Y	337	Missense	distal	5	no	3.566	3.575	EPSD	TCGA;ICGC;COSMIC	1.803	Up-regulation
AGC_RSK_RSKp90_RPS6KA3_ST	Q16821	PPP1R3A	P51812	RPS6KA3	S375	S375Y	375	Missense	central	0	yes	3.509	0.000	EPSD	TCGA;ICGC	1.803	Loss
AGC_RSK_RSKp90_RPS6KA3_ST	Q16821	PPP1R3A	P51812	RPS6KA3	S375	R372K	372	Missense	distal	-3	no	3.509	1.542	EPSD	TCGA;ICGC;COSMIC	1.803	Loss
AGC_RSK_RSKp90_RPS6KA3_ST	Q16821	PPP1R3A	P51812	RPS6KA3	S375	P376S	376	Missense	proximal	1	no	3.509	3.469	EPSD	TCGA;ICGC;COSMIC	1.803	Down-regulation
AGC_RSK_RSKp90_RPS6KA3_ST	Q16821	PPP1R3A	P51812	RPS6KA3	S377	S375Y	375	Missense	proximal	-2	no	2.147	1.994	EPSD	TCGA;ICGC	1.803	Down-regulation
AGC_RSK_RSKp90_RPS6KA3_ST	Q16821	PPP1R3A	P51812	RPS6KA3	S377	R372K	372	Missense	distal	-5	no	2.147	1.859	EPSD	TCGA;ICGC;COSMIC	1.803	Down-regulation
AGC_RSK_RSKp90_RPS6KA3_ST	Q16821	PPP1R3A	P51812	RPS6KA3	S377	P376S	376	Missense	proximal	-1	no	2.147	2.173	EPSD	TCGA;ICGC;COSMIC	1.803	Up-regulation
AGC_RSK_RSKp90_RPS6KA3_ST	Q16821	PPP1R3A	P51812	RPS6KA3	S377	V384I	384	Missense	distal	7	no	2.147	2.136	EPSD	TCGA;ICGC;COSMIC;GDSC	1.803	Down-regulation
AGC_RSK_RSKp90_RPS6KA3_ST	Q16821	PPP1R3A	P51812	RPS6KA3	T578	T574N	574	Missense	distal	-4	no	1.750	1.806	EPSD	TCGA;ICGC;COSMIC	1.803	Gain
AGC_RSK_RSKp90_RPS6KA3_ST	Q16821	PPP1R3A	P51812	RPS6KA3	S979	V976A	976	Missense	distal	-3	no	1.277	1.990	EPSD	TCGA;ICGC;COSMIC	1.803	Gain
AGC_RSK_RSKp90_RPS6KA3_ST	P32314	FOXN2	P51812	RPS6KA3	T15	I21N	21	Missense	distal	6	no	1.918	1.928	EPSD	TCGA;ICGC;COSMIC	1.803	Up-regulation
AGC_RSK_RSKp90_RPS6KA3_ST	P32314	FOXN2	P51812	RPS6KA3	T15	A22S	22	Missense	distal	7	no	1.918	1.900	EPSD	TCGA;ICGC;COSMIC	1.803	Down-regulation
AGC_RSK_RSKp90_RPS6KA3_ST	P32314	FOXN2	P51812	RPS6KA3	T15	K20N	20	Missense	distal	5	no	1.918	1.944	EPSD	TCGA;ICGC;COSMIC;GDSC;CCLE	1.803	Up-regulation
AGC_RSK_RSKp90_RPS6KA3_ST	P32314	FOXN2	P51812	RPS6KA3	S273	G275S	275	Missense	proximal	2	no	1.743	1.828	EPSD	TCGA	1.803	Gain
AGC_RSK_RSKp90_RPS6KA3_ST	P40763	STAT3	P51812	RPS6KA3	S691	Y686D	686	Missense	distal	-5	no	3.562	3.559	EPSD	TCGA;ICGC	1.803	Down-regulation
AGC_RSK_RSKp90_RPS6KA3_ST	P40763	STAT3	P51812	RPS6KA3	S727	R729H	729	Missense	proximal	2	no	2.103	2.002	PhosphoSitePlus	TCGA;ICGC;COSMIC;GDSC;CCLE	1.803	Down-regulation
AGC_RSK_RSKp90_RPS6KA3_ST	P40763	STAT3	P51812	RPS6KA3	S727	P725L	725	Missense	proximal	-2	no	2.103	2.067	PhosphoSitePlus	TCGA;ICGC;COSMIC	1.803	Down-regulation
AGC_RSK_RSKp90_RPS6KA3_ST	P16949	STMN1	P51812	RPS6KA3	S63	E58D	58	Missense	distal	-5	no	4.110	4.086	EPSD	TCGA;ICGC;COSMIC	1.803	Down-regulation
AGC_RSK_RSKp90_RPS6KA3_ST	P16949	STMN1	P51812	RPS6KA3	S63	A66G	66	Missense	distal	3	no	4.110	4.114	EPSD	TCGA;ICGC;COSMIC	1.803	Up-regulation
AGC_RSK_RSKp90_RPS6KA3_ST	P16949	STMN1	P51812	RPS6KA3	S63	R61H	61	Missense	proximal	-2	no	4.110	3.554	EPSD	TCGA;ICGC;COSMIC	1.803	Down-regulation
AGC_RSK_RSKp90_RPS6KA3_ST	P16949	STMN1	P51812	RPS6KA3	S63	S63P	63	Missense	central	0	yes	4.110	0.000	EPSD	TCGA;ICGC;COSMIC	1.803	Loss
AGC_RSK_RSKp90_RPS6KA3_ST	P29317	EPHA2	P51812	RPS6KA3	S433	Q436H	436	Missense	distal	3	no	1.959	1.961	EPSD	TCGA;ICGC;COSMIC	1.803	Up-regulation
AGC_RSK_RSKp90_RPS6KA3_ST	P29317	EPHA2	P51812	RPS6KA3	S570	R568H	568	Missense	proximal	-2	no	2.155	1.599	EPSD	TCGA;ICGC;COSMIC	1.803	Loss
AGC_RSK_RSKp90_RPS6KA3_ST	P29317	EPHA2	P51812	RPS6KA3	S790	E787K	787	Missense	distal	-3	no	1.651	2.125	EPSD	TCGA;ICGC;COSMIC	1.803	Gain
AGC_RSK_RSKp90_RPS6KA3_ST	P29317	EPHA2	P51812	RPS6KA3	S897	S899G	899	Missense	proximal	2	no	3.710	3.624	PhosphoSitePlus	TCGA;ICGC;COSMIC	1.803	Down-regulation
AGC_RSK_RSKp90_RPS6KA3_ST	P29317	EPHA2	P51812	RPS6KA3	S899	S899G	899	Missense	central	0	yes	2.455	0.000	EPSD	TCGA;ICGC;COSMIC	1.803	Loss
AGC_RSK_RSKp90_RPS6KA3_ST	P29317	EPHA2	P51812	RPS6KA3	S910	R907S	907	Missense	distal	-3	no	3.449	1.441	EPSD	TCGA;ICGC;COSMIC	1.803	Loss
AGC_RSK_RSKp90_RPS6KA3_ST	P48764	SLC9A3	P51812	RPS6KA3	S555	S561Y	561	Missense	distal	6	no	3.739	3.684	EPSD	TCGA;COSMIC	1.803	Down-regulation
AGC_RSK_RSKp90_RPS6KA3_ST	P48764	SLC9A3	P51812	RPS6KA3	S555	R553C	553	Missense	proximal	-2	no	3.739	3.158	EPSD	TCGA;COSMIC	1.803	Down-regulation
AGC_RSK_RSKp90_RPS6KA3_ST	P48764	SLC9A3	P51812	RPS6KA3	S555	R553H	553	Missense	proximal	-2	no	3.739	3.183	EPSD	TCGA;COSMIC	1.803	Down-regulation
AGC_RSK_RSKp90_RPS6KA3_ST	P48764	SLC9A3	P51812	RPS6KA3	S563	V570M	570	Missense	distal	7	no	3.937	3.920	EPSD	TCGA;COSMIC	1.803	Down-regulation
AGC_RSK_RSKp90_RPS6KA3_ST	P48764	SLC9A3	P51812	RPS6KA3	S563	S561Y	561	Missense	proximal	-2	no	3.937	3.785	EPSD	TCGA;COSMIC	1.803	Down-regulation
AGC_RSK_RSKp90_RPS6KA3_ST	P48764	SLC9A3	P51812	RPS6KA3	S563	V568I	568	Missense	distal	5	no	3.937	3.919	EPSD	TCGA;COSMIC	1.803	Down-regulation
AGC_RSK_RSKp90_RPS6KA3_ST	P48764	SLC9A3	P51812	RPS6KA3	S663	S663Y	663	Missense	central	0	yes	4.081	0.000	PhosphoSitePlus	TCGA	1.803	Loss
AGC_RSK_RSKp90_RPS6KA3_ST	P48764	SLC9A3	P51812	RPS6KA3	S663	R660H	660	Missense	distal	-3	no	4.081	1.543	PhosphoSitePlus	TCGA;COSMIC	1.803	Loss
AGC_RSK_RSKp90_RPS6KA3_ST	P48764	SLC9A3	P51812	RPS6KA3	S663	S666L	666	Missense	distal	3	no	4.081	4.090	PhosphoSitePlus	TCGA;COSMIC	1.803	Up-regulation
AGC_RSK_RSKp90_RPS6KA3_ST	P48764	SLC9A3	P51812	RPS6KA3	S831	P829T	829	Missense	proximal	-2	no	1.813	1.732	EPSD	TCGA;COSMIC	1.803	Loss
AGC_RSK_RSKp90_RPS6KA3_ST	P48764	SLC9A3	P51812	RPS6KA3	S831	A827T	827	Missense	distal	-4	no	1.813	1.733	EPSD	TCGA;COSMIC	1.803	Loss
AGC_RSK_RSKp90_RPS6KA3_ST	Q96RK0	CIC	P51812	RPS6KA3	S142	E143K	143	Missense	proximal	1	no	3.738	3.715	EPSD	TCGA;COSMIC	1.803	Down-regulation
AGC_RSK_RSKp90_RPS6KA3_ST	Q96RK0	CIC	P51812	RPS6KA3	S142	E145K	145	Missense	distal	3	no	3.738	3.736	EPSD	TCGA;COSMIC	1.803	Down-regulation
AGC_RSK_RSKp90_RPS6KA3_ST	Q96RK0	CIC	P51812	RPS6KA3	S142	E145Q	145	Missense	distal	3	no	3.738	3.737	EPSD	TCGA;COSMIC	1.803	Down-regulation
AGC_RSK_RSKp90_RPS6KA3_ST	Q96RK0	CIC	P51812	RPS6KA3	S142	R139W	139	Missense	distal	-3	no	3.738	1.196	EPSD	TCGA;COSMIC	1.803	Loss
AGC_RSK_RSKp90_RPS6KA3_ST	Q96RK0	CIC	P51812	RPS6KA3	S173	R169C	169	Missense	distal	-4	no	3.665	3.466	PhosphoSitePlus	TCGA;COSMIC	1.803	Down-regulation
AGC_RSK_RSKp90_RPS6KA3_ST	Q96RK0	CIC	P51812	RPS6KA3	S175	R169C	169	Missense	distal	-6	no	1.834	1.747	EPSD	TCGA;COSMIC	1.803	Loss
AGC_RSK_RSKp90_RPS6KA3_ST	Q96RK0	CIC	P51812	RPS6KA3	S175	R181Q	181	Missense	distal	6	no	1.834	1.777	EPSD	TCGA;COSMIC	1.803	Loss
AGC_RSK_RSKp90_RPS6KA3_ST	Q96RK0	CIC	P51812	RPS6KA3	S231	V230I	230	Missense	proximal	-1	no	3.134	3.146	EPSD	TCGA;COSMIC	1.803	Up-regulation
AGC_RSK_RSKp90_RPS6KA3_ST	Q96RK0	CIC	P51812	RPS6KA3	S231	L234Q	234	Missense	distal	3	no	3.134	3.130	EPSD	TCGA;COSMIC	1.803	Down-regulation
AGC_RSK_RSKp90_RPS6KA3_ST	Q96RK0	CIC	P51812	RPS6KA3	S231	G235D	235	Missense	distal	4	no	3.134	3.131	EPSD	TCGA;COSMIC	1.803	Down-regulation
AGC_RSK_RSKp90_RPS6KA3_ST	Q96RK0	CIC	P51812	RPS6KA3	S231	R228W	228	Missense	distal	-3	no	3.134	0.592	EPSD	TCGA;COSMIC	1.803	Loss
AGC_RSK_RSKp90_RPS6KA3_ST	Q96RK0	CIC	P51812	RPS6KA3	S231	T229P	229	Missense	proximal	-2	no	3.134	3.215	EPSD	TCGA;COSMIC	1.803	Up-regulation
AGC_RSK_RSKp90_RPS6KA3_ST	Q96RK0	CIC	P51812	RPS6KA3	S231	S231G	231	Missense	central	0	yes	3.134	0.000	EPSD	TCGA;COSMIC	1.803	Loss
AGC_RSK_RSKp90_RPS6KA3_ST	Q96RK0	CIC	P51812	RPS6KA3	S231	N227I	227	Missense	distal	-4	no	3.134	3.106	EPSD	TCGA;COSMIC	1.803	Down-regulation
AGC_RSK_RSKp90_RPS6KA3_ST	Q96RK0	CIC	P51812	RPS6KA3	S231	S231I	231	Missense	central	0	yes	3.134	0.000	EPSD	TCGA;COSMIC	1.803	Loss
AGC_RSK_RSKp90_RPS6KA3_ST	Q96RK0	CIC	P51812	RPS6KA3	S231	K232E	232	Missense	proximal	1	no	3.134	3.157	EPSD	TCGA;COSMIC	1.803	Up-regulation
AGC_RSK_RSKp90_RPS6KA3_ST	Q96RK0	CIC	P51812	RPS6KA3	S231	R228Q	228	Missense	distal	-3	no	3.134	0.627	EPSD	TCGA;COSMIC	1.803	Loss
AGC_RSK_RSKp90_RPS6KA3_ST	Q96RK0	CIC	P51812	RPS6KA3	S277	S278N	278	Missense	proximal	1	no	4.091	4.127	EPSD	TCGA;COSMIC	1.803	Up-regulation
AGC_RSK_RSKp90_RPS6KA3_ST	Q96RK0	CIC	P51812	RPS6KA3	S277	R274Q	274	Missense	distal	-3	no	4.091	1.584	EPSD	TCGA;COSMIC	1.803	Loss
AGC_RSK_RSKp90_RPS6KA3_ST	Q96RK0	CIC	P51812	RPS6KA3	S277	S277Y	277	Missense	central	0	yes	4.091	0.000	EPSD	TCGA	1.803	Loss
AGC_RSK_RSKp90_RPS6KA3_ST	Q96RK0	CIC	P51812	RPS6KA3	S279	S278N	278	Missense	proximal	-1	no	2.543	2.514	EPSD	TCGA;COSMIC	1.803	Down-regulation
AGC_RSK_RSKp90_RPS6KA3_ST	Q96RK0	CIC	P51812	RPS6KA3	S279	R274Q	274	Missense	distal	-5	no	2.543	2.181	EPSD	TCGA;COSMIC	1.803	Down-regulation
AGC_RSK_RSKp90_RPS6KA3_ST	Q96RK0	CIC	P51812	RPS6KA3	S279	S277Y	277	Missense	proximal	-2	no	2.543	2.390	EPSD	TCGA	1.803	Down-regulation
AGC_RSK_RSKp90_RPS6KA3_ST	Q96RK0	CIC	P51812	RPS6KA3	S285	S278N	278	Missense	distal	-7	no	1.803	1.815	EPSD	TCGA;COSMIC	1.803	Up-regulation
AGC_RSK_RSKp90_RPS6KA3_ST	Q96RK0	CIC	P51812	RPS6KA3	S299	R298Q	298	Missense	proximal	-1	no	3.678	3.620	EPSD	TCGA;COSMIC	1.803	Down-regulation
AGC_RSK_RSKp90_RPS6KA3_ST	Q96RK0	CIC	P51812	RPS6KA3	S299	S301P	301	Missense	proximal	2	no	3.678	3.607	EPSD	TCGA;COSMIC	1.803	Down-regulation
AGC_RSK_RSKp90_RPS6KA3_ST	Q96RK0	CIC	P51812	RPS6KA3	S299	S301L	301	Missense	proximal	2	no	3.678	3.571	EPSD	TCGA;COSMIC	1.803	Down-regulation
AGC_RSK_RSKp90_RPS6KA3_ST	Q96RK0	CIC	P51812	RPS6KA3	S299	R296W	296	Missense	distal	-3	no	3.678	1.136	EPSD	TCGA;COSMIC	1.803	Loss
AGC_RSK_RSKp90_RPS6KA3_ST	Q96RK0	CIC	P51812	RPS6KA3	S301	R298Q	298	Missense	distal	-3	no	4.114	1.608	EPSD	TCGA;COSMIC	1.803	Loss
AGC_RSK_RSKp90_RPS6KA3_ST	Q96RK0	CIC	P51812	RPS6KA3	S301	S301P	301	Missense	central	0	yes	4.114	0.000	EPSD	TCGA;COSMIC	1.803	Loss
AGC_RSK_RSKp90_RPS6KA3_ST	Q96RK0	CIC	P51812	RPS6KA3	S301	S301L	301	Missense	central	0	yes	4.114	0.000	EPSD	TCGA;COSMIC	1.803	Loss
AGC_RSK_RSKp90_RPS6KA3_ST	Q96RK0	CIC	P51812	RPS6KA3	S301	R296W	296	Missense	distal	-5	no	4.114	3.732	EPSD	TCGA;COSMIC	1.803	Down-regulation
AGC_RSK_RSKp90_RPS6KA3_ST	Q96RK0	CIC	P51812	RPS6KA3	S334	S335F	335	Missense	proximal	1	no	2.036	2.120	EPSD	TCGA;ICGC;COSMIC	1.803	Up-regulation
AGC_RSK_RSKp90_RPS6KA3_ST	Q96RK0	CIC	P51812	RPS6KA3	S334	R340W	340	Missense	distal	6	no	2.036	1.968	EPSD	TCGA;ICGC;COSMIC;GDSC	1.803	Down-regulation
AGC_RSK_RSKp90_RPS6KA3_ST	Q96RK0	CIC	P51812	RPS6KA3	T343	S349L	349	Missense	distal	6	no	2.613	2.560	EPSD	TCGA	1.803	Down-regulation
AGC_RSK_RSKp90_RPS6KA3_ST	Q96RK0	CIC	P51812	RPS6KA3	T343	R340W	340	Missense	distal	-3	no	2.613	0.071	EPSD	TCGA;ICGC;COSMIC;GDSC	1.803	Loss
AGC_RSK_RSKp90_RPS6KA3_ST	Q96RK0	CIC	P51812	RPS6KA3	S356	S349L	349	Missense	distal	-7	no	4.102	4.121	EPSD	TCGA	1.803	Up-regulation
AGC_RSK_RSKp90_RPS6KA3_ST	Q96RK0	CIC	P51812	RPS6KA3	S424	R428H	428	Missense	distal	4	no	1.837	1.890	EPSD	TCGA;ICGC;COSMIC	1.803	Up-regulation
AGC_RSK_RSKp90_RPS6KA3_ST	Q96RK0	CIC	P51812	RPS6KA3	S424	P417S	417	Missense	distal	-7	no	1.837	1.827	EPSD	TCGA;ICGC;COSMIC	1.803	Down-regulation
AGC_RSK_RSKp90_RPS6KA3_ST	Q96RK0	CIC	P51812	RPS6KA3	S424	A430T	430	Missense	distal	6	no	1.837	1.801	EPSD	TCGA;ICGC;COSMIC	1.803	Loss
AGC_RSK_RSKp90_RPS6KA3_ST	Q96RK0	CIC	P51812	RPS6KA3	S424	R422Q	422	Missense	proximal	-2	no	1.837	1.312	EPSD	TCGA;ICGC;COSMIC	1.803	Loss
AGC_RSK_RSKp90_RPS6KA3_ST	Q96RK0	CIC	P51812	RPS6KA3	S426	D433N	433	Missense	distal	7	no	1.932	1.920	EPSD	TCGA;ICGC;COSMIC	1.803	Down-regulation
AGC_RSK_RSKp90_RPS6KA3_ST	Q96RK0	CIC	P51812	RPS6KA3	S426	R428H	428	Missense	proximal	2	no	1.932	1.831	EPSD	TCGA;ICGC;COSMIC	1.803	Down-regulation
AGC_RSK_RSKp90_RPS6KA3_ST	Q96RK0	CIC	P51812	RPS6KA3	S426	A430T	430	Missense	distal	4	no	1.932	1.983	EPSD	TCGA;ICGC;COSMIC	1.803	Up-regulation
AGC_RSK_RSKp90_RPS6KA3_ST	Q96RK0	CIC	P51812	RPS6KA3	S426	R422Q	422	Missense	distal	-4	no	1.932	1.766	EPSD	TCGA;ICGC;COSMIC	1.803	Loss
AGC_RSK_RSKp90_RPS6KA3_ST	Q96RK0	CIC	P51812	RPS6KA3	S431	D433N	433	Missense	proximal	2	no	3.621	3.644	EPSD	TCGA;ICGC;COSMIC	1.803	Up-regulation
AGC_RSK_RSKp90_RPS6KA3_ST	Q96RK0	CIC	P51812	RPS6KA3	S431	R428H	428	Missense	distal	-3	no	3.621	1.083	EPSD	TCGA;ICGC;COSMIC	1.803	Loss
AGC_RSK_RSKp90_RPS6KA3_ST	Q96RK0	CIC	P51812	RPS6KA3	S431	M434I	434	Missense	distal	3	no	3.621	3.622	EPSD	TCGA;ICGC;COSMIC	1.803	Up-regulation
AGC_RSK_RSKp90_RPS6KA3_ST	Q96RK0	CIC	P51812	RPS6KA3	S431	A430T	430	Missense	proximal	-1	no	3.621	3.592	EPSD	TCGA;ICGC;COSMIC	1.803	Down-regulation
AGC_RSK_RSKp90_RPS6KA3_ST	Q96RK0	CIC	P51812	RPS6KA3	S496	R492W	492	Missense	distal	-4	no	1.897	1.706	EPSD	TCGA;ICGC;COSMIC	1.803	Loss
AGC_RSK_RSKp90_RPS6KA3_ST	Q96RK0	CIC	P51812	RPS6KA3	S496	F495L	495	Missense	proximal	-1	no	1.897	1.915	EPSD	TCGA;ICGC;COSMIC	1.803	Up-regulation
AGC_RSK_RSKp90_RPS6KA3_ST	Q96RK0	CIC	P51812	RPS6KA3	S496	S502F	502	Missense	distal	6	no	1.897	1.828	EPSD	TCGA;ICGC;COSMIC	1.803	Down-regulation
AGC_RSK_RSKp90_RPS6KA3_ST	Q96RK0	CIC	P51812	RPS6KA3	S496	S501F	501	Missense	distal	5	no	1.897	1.996	EPSD	TCGA;ICGC;COSMIC	1.803	Up-regulation
AGC_RSK_RSKp90_RPS6KA3_ST	Q96RK0	CIC	P51812	RPS6KA3	S496	R492Q	492	Missense	distal	-4	no	1.897	1.731	EPSD	TCGA;ICGC;COSMIC	1.803	Loss
AGC_RSK_RSKp90_RPS6KA3_ST	Q96RK0	CIC	P51812	RPS6KA3	S538	S543L	543	Missense	distal	5	no	1.807	1.886	EPSD	TCGA;ICGC;COSMIC	1.803	Up-regulation
AGC_RSK_RSKp90_RPS6KA3_ST	Q96RK0	CIC	P51812	RPS6KA3	S541	S543L	543	Missense	proximal	2	no	1.907	1.800	EPSD	TCGA;ICGC;COSMIC	1.803	Loss
AGC_RSK_RSKp90_RPS6KA3_ST	Q96RK0	CIC	P51812	RPS6KA3	S543	S543L	543	Missense	central	0	yes	2.204	0.000	EPSD	TCGA;ICGC;COSMIC	1.803	Loss
AGC_RSK_RSKp90_RPS6KA3_ST	Q96RK0	CIC	P51812	RPS6KA3	S605	P611L	611	Missense	distal	6	no	3.884	3.866	EPSD	TCGA;ICGC;COSMIC	1.803	Down-regulation
AGC_RSK_RSKp90_RPS6KA3_ST	Q96RK0	CIC	P51812	RPS6KA3	S605	R600H	600	Missense	distal	-5	no	3.884	3.501	EPSD	TCGA;ICGC;COSMIC	1.803	Down-regulation
AGC_RSK_RSKp90_RPS6KA3_ST	Q96RK0	CIC	P51812	RPS6KA3	S605	V606M	606	Missense	proximal	1	no	3.884	3.852	EPSD	TCGA;ICGC;COSMIC	1.803	Down-regulation
AGC_RSK_RSKp90_RPS6KA3_ST	Q96RK0	CIC	P51812	RPS6KA3	S739	H743L	743	Missense	distal	4	no	1.976	1.990	EPSD	TCGA;ICGC;COSMIC	1.803	Up-regulation
AGC_RSK_RSKp90_RPS6KA3_ST	Q96RK0	CIC	P51812	RPS6KA3	S739	P742L	742	Missense	distal	3	no	1.976	1.979	EPSD	TCGA;ICGC;COSMIC	1.803	Up-regulation
AGC_RSK_RSKp90_RPS6KA3_ST	Q96RK0	CIC	P51812	RPS6KA3	S739	A737T	737	Missense	proximal	-2	no	1.976	1.878	EPSD	TCGA;ICGC;COSMIC	1.803	Down-regulation
AGC_RSK_RSKp90_RPS6KA3_ST	Q96RK0	CIC	P51812	RPS6KA3	S739	A746V	746	Missense	distal	7	no	1.976	2.007	EPSD	TCGA;ICGC;COSMIC	1.803	Up-regulation
AGC_RSK_RSKp90_RPS6KA3_ST	Q96RK0	CIC	P51812	RPS6KA3	S902	P909Q	909	Missense	distal	7	no	1.899	1.898	EPSD	TCGA;ICGC;COSMIC	1.803	Down-regulation
AGC_RSK_RSKp90_RPS6KA3_ST	Q96RK0	CIC	P51812	RPS6KA3	S902	A900P	900	Missense	proximal	-2	no	1.899	1.882	EPSD	TCGA;ICGC;COSMIC	1.803	Down-regulation
AGC_RSK_RSKp90_RPS6KA3_ST	Q96RK0	CIC	P51812	RPS6KA3	S902	P905L	905	Missense	distal	3	no	1.899	1.902	EPSD	TCGA;ICGC;COSMIC	1.803	Up-regulation
AGC_RSK_RSKp90_RPS6KA3_ST	Q96RK0	CIC	P51812	RPS6KA3	S982	V978M	978	Missense	distal	-4	no	1.945	1.994	EPSD	TCGA;ICGC;COSMIC	1.803	Up-regulation
AGC_RSK_RSKp90_RPS6KA3_ST	Q96RK0	CIC	P51812	RPS6KA3	T1217	E1224Q	1224	Missense	distal	7	no	1.921	1.914	EPSD	TCGA;ICGC;COSMIC	1.803	Down-regulation
AGC_RSK_RSKp90_RPS6KA3_ST	Q96RK0	CIC	P51812	RPS6KA3	S1246	A1243T	1243	Missense	distal	-3	no	1.922	1.594	EPSD	TCGA	1.803	Loss
AGC_RSK_RSKp90_RPS6KA3_ST	Q96RK0	CIC	P51812	RPS6KA3	S1351	R1358C	1358	Missense	distal	7	no	3.301	3.355	EPSD	TCGA;ICGC;COSMIC	1.803	Up-regulation
AGC_RSK_RSKp90_RPS6KA3_ST	Q96RK0	CIC	P51812	RPS6KA3	S1351	E1356K	1356	Missense	distal	5	no	3.301	3.276	EPSD	TCGA;ICGC;COSMIC	1.803	Down-regulation
AGC_RSK_RSKp90_RPS6KA3_ST	Q96RK0	CIC	P51812	RPS6KA3	S1397	A1403T	1403	Missense	distal	6	no	4.077	4.041	EPSD	TCGA;COSMIC	1.803	Down-regulation
AGC_RSK_RSKp90_RPS6KA3_ST	Q96RK0	CIC	P51812	RPS6KA3	S1397	T1398M	1398	Missense	proximal	1	no	4.077	4.043	EPSD	TCGA;ICGC;COSMIC	1.803	Down-regulation
AGC_RSK_RSKp90_RPS6KA3_ST	Q96RK0	CIC	P51812	RPS6KA3	S1397	R1391H	1391	Missense	distal	-6	no	4.077	3.998	EPSD	TCGA;ICGC;COSMIC	1.803	Down-regulation
AGC_RSK_RSKp90_RPS6KA3_ST	Q96RK0	CIC	P51812	RPS6KA3	S1418	R1412L	1412	Missense	distal	-6	no	4.322	4.239	EPSD	TCGA;COSMIC	1.803	Down-regulation
AGC_RSK_RSKp90_RPS6KA3_ST	Q96RK0	CIC	P51812	RPS6KA3	S1418	R1417C	1417	Missense	proximal	-1	no	4.322	4.248	EPSD	TCGA;COSMIC	1.803	Down-regulation
AGC_RSK_RSKp90_RPS6KA3_ST	Q96RK0	CIC	P51812	RPS6KA3	S1419	R1412L	1412	Missense	distal	-7	no	4.181	4.210	EPSD	TCGA;COSMIC	1.803	Up-regulation
AGC_RSK_RSKp90_RPS6KA3_ST	Q96RK0	CIC	P51812	RPS6KA3	S1419	R1417C	1417	Missense	proximal	-2	no	4.181	3.600	EPSD	TCGA;COSMIC	1.803	Down-regulation
AGC_RSK_RSKp90_RPS6KA3_ST	Q96RK0	CIC	P51812	RPS6KA3	S1421	R1417C	1417	Missense	distal	-4	no	2.094	1.894	EPSD	TCGA;COSMIC	1.803	Down-regulation
AGC_RSK_RSKp90_RPS6KA3_ST	Q96RK0	CIC	P51812	RPS6KA3	S1422	S1429I	1429	Missense	distal	7	no	1.966	2.005	EPSD	TCGA;ICGC	1.803	Up-regulation
AGC_RSK_RSKp90_RPS6KA3_ST	Q96RK0	CIC	P51812	RPS6KA3	S1422	R1417C	1417	Missense	distal	-5	no	1.966	1.565	EPSD	TCGA;COSMIC	1.803	Loss
AGC_RSK_RSKp90_RPS6KA3_ST	P25963	NFKBIA	P51812	RPS6KA3	S32	D31N	31	Missense	proximal	-1	no	3.469	3.482	PhosphoSitePlus	TCGA;ICGC;COSMIC	1.803	Up-regulation
AGC_RSK_RSKp90_RPS6KA3_ST	P25963	NFKBIA	P51812	RPS6KA3	S32	D27H	27	Missense	distal	-5	no	3.469	3.480	PhosphoSitePlus	TCGA;ICGC;COSMIC	1.803	Up-regulation
AGC_RSK_RSKp90_RPS6KA3_ST	P25963	NFKBIA	P51812	RPS6KA3	S166	L163R	163	Missense	distal	-3	no	1.203	3.433	EPSD	TCGA;COSMIC	1.803	Gain
AGC_RSK_RSKp90_RPS6KA3_ST	P05198	EIF2S1	P51812	RPS6KA3	S58	R57C	57	Missense	proximal	-1	no	4.028	3.955	EPSD	TCGA;ICGC;COSMIC	1.803	Down-regulation
AGC_RSK_RSKp90_RPS6KA3_ST	P05198	EIF2S1	P51812	RPS6KA3	S91	L85V	85	Missense	distal	-6	no	3.952	3.941	EPSD	TCGA;ICGC;COSMIC	1.803	Down-regulation
AGC_RSK_RSKp90_RPS6KA3_ST	P05198	EIF2S1	P51812	RPS6KA3	T185	R192Q	192	Missense	distal	7	no	2.237	2.274	EPSD	TCGA;ICGC;COSMIC	1.803	Up-regulation
AGC_RSK_RSKp90_RPS6KA3_ST	P05198	EIF2S1	P51812	RPS6KA3	T185	L184F	184	Missense	proximal	-1	no	2.237	2.218	EPSD	TCGA;ICGC;COSMIC	1.803	Down-regulation
AGC_RSK_RSKp90_RPS6KA3_ST	P49840	GSK3A	P51812	RPS6KA3	S278	R283H	283	Missense	distal	5	no	1.760	1.853	EPSD	TCGA;ICGC;COSMIC	1.803	Gain
AGC_RSK_RSKp90_RPS6KA3_ST	O14649	KCNK3	P51812	RPS6KA3	S372	A366V	366	Missense	distal	-6	no	2.159	2.125	EPSD	TCGA;ICGC;COSMIC;CCLE	1.803	Down-regulation
AGC_RSK_RSKp90_RPS6KA3_ST	O14649	KCNK3	P51812	RPS6KA3	S373	A366V	366	Missense	distal	-7	no	2.219	2.233	EPSD	TCGA;ICGC;COSMIC;CCLE	1.803	Up-regulation
AGC_RSK_RSKp90_RPS6KA3_ST	O14649	KCNK3	P51812	RPS6KA3	S373	S380N	380	Missense	distal	7	no	2.219	2.248	EPSD	TCGA;ICGC	1.803	Up-regulation
CK1_TTBK_TTBK2_ST	Q7L0J3	SV2A	Q6IQ55	TTBK2	S42	S47C	47	Missense	distal	5	no	7.526	6.054	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	3.341	Down-regulation
CK1_TTBK_TTBK2_ST	Q7L0J3	SV2A	Q6IQ55	TTBK2	S42	E40K	40	Missense	proximal	-2	no	7.526	7.563	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	3.341	Up-regulation
CK1_TTBK_TTBK2_ST	Q7L0J3	SV2A	Q6IQ55	TTBK2	S42	Y46H	46	Missense	distal	4	no	7.526	7.447	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	3.341	Down-regulation
CK1_TTBK_TTBK2_ST	Q7L0J3	SV2A	Q6IQ55	TTBK2	S45	S47C	47	Missense	proximal	2	no	7.586	7.692	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	3.341	Up-regulation
CK1_TTBK_TTBK2_ST	Q7L0J3	SV2A	Q6IQ55	TTBK2	S45	E40K	40	Missense	distal	-5	no	7.586	6.755	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	3.341	Down-regulation
CK1_TTBK_TTBK2_ST	Q7L0J3	SV2A	Q6IQ55	TTBK2	S45	Y46H	46	Missense	proximal	1	no	7.586	7.567	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	3.341	Down-regulation
CK1_TTBK_TTBK2_ST	Q7L0J3	SV2A	Q6IQ55	TTBK2	S47	S47C	47	Missense	central	0	yes	7.658	0.000	PhosphoSitePlus;EPSD	TCGA;ICGC;COSMIC	3.341	Loss
CK1_TTBK_TTBK2_ST	Q7L0J3	SV2A	Q6IQ55	TTBK2	S47	E40K	40	Missense	distal	-7	no	7.658	7.070	PhosphoSitePlus;EPSD	TCGA;ICGC;COSMIC	3.341	Down-regulation
CK1_TTBK_TTBK2_ST	Q7L0J3	SV2A	Q6IQ55	TTBK2	S47	Y46H	46	Missense	proximal	-1	no	7.658	7.657	PhosphoSitePlus;EPSD	TCGA;ICGC;COSMIC	3.341	Down-regulation
CK1_TTBK_TTBK2_ST	Q7L0J3	SV2A	Q6IQ55	TTBK2	S80	G77C	77	Missense	distal	-3	no	6.833	6.848	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	3.341	Up-regulation
CK1_TTBK_TTBK2_ST	Q7L0J3	SV2A	Q6IQ55	TTBK2	S80	G77S	77	Missense	distal	-3	no	6.833	6.812	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	3.341	Down-regulation
CK1_TTBK_TTBK2_ST	Q7L0J3	SV2A	Q6IQ55	TTBK2	S80	E76K	76	Missense	distal	-4	no	6.833	6.937	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	3.341	Up-regulation
CK1_TTBK_TTBK2_ST	Q7L0J3	SV2A	Q6IQ55	TTBK2	S81	G77C	77	Missense	distal	-4	no	7.524	7.558	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	3.341	Up-regulation
CK1_TTBK_TTBK2_ST	Q7L0J3	SV2A	Q6IQ55	TTBK2	S81	G77S	77	Missense	distal	-4	no	7.524	7.482	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	3.341	Down-regulation
CK1_TTBK_TTBK2_ST	Q7L0J3	SV2A	Q6IQ55	TTBK2	S81	E76K	76	Missense	distal	-5	no	7.524	6.693	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	3.341	Down-regulation
CK1_TTBK_TTBK2_ST	Q7L0J3	SV2A	Q6IQ55	TTBK2	T84	G77C	77	Missense	distal	-7	no	6.838	6.612	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	3.341	Down-regulation
CK1_TTBK_TTBK2_ST	Q7L0J3	SV2A	Q6IQ55	TTBK2	T84	G77S	77	Missense	distal	-7	no	6.838	7.049	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	3.341	Up-regulation
CK1_TTBK_TTBK2_ST	Q7L0J3	SV2A	Q6IQ55	TTBK2	S482	K485E	485	Missense	distal	3	no	3.525	3.476	EPSD	TCGA;ICGC;COSMIC	3.341	Down-regulation
CK1_TTBK_TTBK2_ST	Q7L0J3	SV2A	Q6IQ55	TTBK2	S482	G489E	489	Missense	distal	7	no	3.525	3.445	EPSD	TCGA;ICGC;COSMIC	3.341	Down-regulation
CK1_TTBK_TTBK2_ST	Q7L0J3	SV2A	Q6IQ55	TTBK2	S482	S482F	482	Missense	central	0	yes	3.525	0.000	EPSD	TCGA;ICGC;COSMIC	3.341	Loss
CK1_TTBK_TTBK2_ST	O00139	KIF2A	Q6IQ55	TTBK2	S121	S121I	121	Missense	central	0	yes	3.670	0.000	EPSD	TCGA;COSMIC	3.341	Loss
CK1_TTBK_TTBK2_ST	O00139	KIF2A	Q6IQ55	TTBK2	S135	D138Y	138	Missense	distal	3	no	6.777	6.820	PhosphoSitePlus	TCGA	3.341	Up-regulation
CK1_TTBK_TTBK2_ST	O00139	KIF2A	Q6IQ55	TTBK2	S135	Q132H	132	Missense	distal	-3	no	6.777	6.772	PhosphoSitePlus	TCGA	3.341	Down-regulation
CK1_TTBK_TTBK2_ST	O00139	KIF2A	Q6IQ55	TTBK2	S157	C159G	159	Missense	proximal	2	no	4.143	4.102	EPSD	TCGA;COSMIC	3.341	Down-regulation
CK1_TTBK_TTBK2_ST	O00139	KIF2A	Q6IQ55	TTBK2	S157	P151S	151	Missense	distal	-6	no	4.143	3.818	EPSD	TCGA;COSMIC	3.341	Down-regulation
CK1_TTBK_TTBK2_ST	O00139	KIF2A	Q6IQ55	TTBK2	S157	S153T	153	Missense	distal	-4	no	4.143	4.211	EPSD	TCGA;COSMIC	3.341	Up-regulation
CK1_TTBK_TTBK2_ST	O00139	KIF2A	Q6IQ55	TTBK2	S157	P152L	152	Missense	distal	-5	no	4.143	4.018	EPSD	TCGA;COSMIC	3.341	Down-regulation
CK1_TTBK_TTBK2_ST	O00139	KIF2A	Q6IQ55	TTBK2	S157	S157Y	157	Missense	central	0	yes	4.143	0.000	EPSD	TCGA	3.341	Loss
CK1_TTBK_TTBK2_ST	O00139	KIF2A	Q6IQ55	TTBK2	S250	K251T	251	Missense	proximal	1	no	3.357	3.366	EPSD	TCGA	3.341	Up-regulation
TK_Tec_BTK_Y	P78347	GTF2I	Q06187	BTK	Y248	Q250E	250	Missense	proximal	2	no	3.535	3.548	PhosphoSitePlus;EPSD	TCGA;ICGC;COSMIC	1.787	Up-regulation
TK_Tec_BTK_Y	P78347	GTF2I	Q06187	BTK	Y248	Y251C	251	Missense	distal	3	no	3.535	3.531	PhosphoSitePlus;EPSD	TCGA;ICGC;COSMIC	1.787	Down-regulation
TK_Tec_BTK_Y	P78347	GTF2I	Q06187	BTK	Y398	G401R	401	Missense	distal	3	no	3.382	3.409	EPSD	TCGA;COSMIC	1.787	Up-regulation
TK_Tec_BTK_Y	P16885	PLCG2	Q06187	BTK	Y753	D754N	754	Missense	proximal	1	no	3.510	3.377	PhosphoSitePlus;EPSD	TCGA;ICGC;COSMIC	1.787	Down-regulation
TK_Tec_BTK_Y	P16885	PLCG2	Q06187	BTK	Y753	D754A	754	Missense	proximal	1	no	3.510	3.419	PhosphoSitePlus;EPSD	TCGA;ICGC;COSMIC	1.787	Down-regulation
TK_Tec_BTK_Y	P16885	PLCG2	Q06187	BTK	Y753	V755I	755	Missense	proximal	2	no	3.510	3.530	PhosphoSitePlus;EPSD	TCGA;ICGC;COSMIC	1.787	Up-regulation
TK_Tec_BTK_Y	P16885	PLCG2	Q06187	BTK	Y759	D754N	754	Missense	distal	-5	no	3.275	3.283	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	1.787	Up-regulation
TK_Tec_BTK_Y	P16885	PLCG2	Q06187	BTK	Y759	D754A	754	Missense	distal	-5	no	3.275	3.198	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	1.787	Down-regulation
TK_Tec_BTK_Y	P16885	PLCG2	Q06187	BTK	Y759	S763N	763	Missense	distal	4	no	3.275	3.293	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	1.787	Up-regulation
TK_Tec_BTK_Y	P16885	PLCG2	Q06187	BTK	Y759	V755I	755	Missense	distal	-4	no	3.275	3.262	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	1.787	Down-regulation
TK_Tec_BTK_Y	P16885	PLCG2	Q06187	BTK	Y1197	E1194D	1194	Missense	distal	-3	no	3.522	3.541	EPSD	TCGA;ICGC;COSMIC	1.787	Up-regulation
TK_Tec_BTK_Y	P16885	PLCG2	Q06187	BTK	Y1197	S1198A	1198	Missense	proximal	1	no	3.522	3.516	EPSD	TCGA;ICGC;COSMIC	1.787	Down-regulation
TK_Tec_BTK_Y	P16885	PLCG2	Q06187	BTK	Y1197	R1201H	1201	Missense	distal	4	no	3.522	3.542	EPSD	TCGA;ICGC;COSMIC	1.787	Up-regulation
TK_Tec_BTK_Y	P16885	PLCG2	Q06187	BTK	Y1217	R1224H	1224	Missense	distal	7	no	3.342	3.363	EPSD	TCGA;ICGC;COSMIC;GDSC	1.787	Up-regulation
TK_Tec_BTK_Y	P58753	TIRAP	Q06187	BTK	Y86	R81H	81	Missense	distal	-5	no	3.268	3.545	EPSD;PhosphoSitePlus	TCGA;ICGC	1.787	Up-regulation
TK_Tec_BTK_Y	P58753	TIRAP	Q06187	BTK	Y86	D85Y	85	Missense	proximal	-1	no	3.268	2.187	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	1.787	Down-regulation
TK_Tec_BTK_Y	P58753	TIRAP	Q06187	BTK	Y187	R192Q	192	Missense	distal	5	no	3.246	3.186	EPSD;PhosphoSitePlus	TCGA;ICGC	1.787	Down-regulation
TK_Tec_BTK_Y	P58753	TIRAP	Q06187	BTK	Y187	A186V	186	Missense	proximal	-1	no	3.246	2.588	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	1.787	Down-regulation
TK_Tec_BTK_Y	Q06187	BTK	Q06187	BTK	Y223	K218N	218	Missense	distal	-5	no	3.703	3.714	PhosphoSitePlus;EPSD	TCGA;ICGC;COSMIC	1.787	Up-regulation
TK_Tec_BTK_Y	Q06187	BTK	Q06187	BTK	Y241	E245K	245	Missense	distal	4	no	1.825	1.896	EPSD	TCGA;ICGC;COSMIC	1.787	Up-regulation
TK_Tec_BTK_Y	Q06187	BTK	Q06187	BTK	Y241	E245Q	245	Missense	distal	4	no	1.825	1.769	EPSD	TCGA;ICGC;COSMIC	1.787	Loss
TK_Tec_BTK_Y	Q06187	BTK	Q06187	BTK	Y241	E246K	246	Missense	distal	5	no	1.825	1.728	EPSD	TCGA;ICGC;COSMIC	1.787	Loss
TK_Tec_BTK_Y	Q06187	BTK	Q06187	BTK	Y375	S371F	371	Missense	distal	-4	no	2.212	2.230	EPSD	TCGA;ICGC;COSMIC	1.787	Up-regulation
TK_Tec_BTK_Y	Q06187	BTK	Q06187	BTK	Y375	P376S	376	Missense	proximal	1	no	2.212	2.046	EPSD	TCGA;ICGC;COSMIC	1.787	Down-regulation
TK_Tec_BTK_Y	Q06187	BTK	Q06187	BTK	Y551	D549N	549	Missense	proximal	-2	no	2.892	2.864	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	1.787	Down-regulation
TK_Tec_BTK_Y	Q06187	BTK	Q06187	BTK	Y617	A622G	622	Missense	distal	5	no	1.915	2.079	EPSD	TCGA;ICGC;COSMIC	1.787	Up-regulation
TK_Tec_BTK_Y	Q06187	BTK	Q06187	BTK	Y617	L614Q	614	Missense	distal	-3	no	1.915	1.833	EPSD	TCGA;ICGC;COSMIC	1.787	Down-regulation
TK_Tec_BTK_Y	Q06187	BTK	Q06187	BTK	Y617	L621M	621	Missense	distal	4	no	1.915	1.866	EPSD	TCGA;ICGC;COSMIC	1.787	Down-regulation
TK_Tec_BTK_Y	Q06187	BTK	Q06187	BTK	Y617	E624K	624	Missense	distal	7	no	1.915	1.944	EPSD	TCGA;ICGC;COSMIC	1.787	Up-regulation
TK_Tec_BTK_Y	Q06187	BTK	Q06187	BTK	Y617	Y617C	617	Missense	central	0	yes	1.915	0.000	EPSD	TCGA;ICGC	1.787	Loss
TK_Tec_BTK_Y	Q08881	ITK	Q06187	BTK	Y180	D181H	181	Missense	proximal	1	no	4.386	4.307	PhosphoSitePlus	TCGA;ICGC;COSMIC	1.787	Down-regulation
TK_Tec_BTK_Y	Q08881	ITK	Q06187	BTK	Y180	P187T	187	Missense	distal	7	no	4.386	4.348	PhosphoSitePlus	TCGA;ICGC;COSMIC;GDSC;CCLE	1.787	Down-regulation
TK_Tec_BTK_Y	Q08881	ITK	Q06187	BTK	Y180	E173K	173	Missense	distal	-7	no	4.386	4.281	PhosphoSitePlus	TCGA;ICGC;COSMIC	1.787	Down-regulation
TK_Tec_BTK_Y	Q08881	ITK	Q06187	BTK	Y180	V175M	175	Missense	distal	-5	no	4.386	4.407	PhosphoSitePlus	TCGA;ICGC	1.787	Up-regulation
TK_Tec_BTK_Y	Q08881	ITK	Q06187	BTK	Y198	E196K	196	Missense	proximal	-2	no	1.647	1.841	EPSD	TCGA;ICGC;COSMIC	1.787	Gain
TK_Tec_BTK_Y	Q08881	ITK	Q06187	BTK	Y198	S203N	203	Missense	distal	5	no	1.647	1.832	EPSD	TCGA;ICGC;COSMIC	1.787	Gain
TK_Tec_BTK_Y	P51813	BMX	Q06187	BTK	Y216	Y216H	216	Missense	central	0	yes	3.101	0.000	PhosphoSitePlus	TCGA;ICGC;COSMIC	1.787	Loss
TK_Tec_BTK_Y	Q9UJV9	DDX41	Q06187	BTK	Y33	E31Q	31	Missense	proximal	-2	no	1.754	1.830	EPSD	TCGA;ICGC;COSMIC	1.787	Gain
TK_Tec_BTK_Y	Q9UJV9	DDX41	Q06187	BTK	Y33	E28Q	28	Missense	distal	-5	no	1.754	1.826	EPSD	TCGA;ICGC;COSMIC	1.787	Gain
TK_Tec_BTK_Y	Q9UJV9	DDX41	Q06187	BTK	Y364	R359S	359	Missense	distal	-5	no	1.711	1.947	EPSD	TCGA;ICGC;COSMIC	1.787	Gain
TK_Tec_BTK_Y	Q9UJV9	DDX41	Q06187	BTK	Y364	R359H	359	Missense	distal	-5	no	1.711	1.989	EPSD	TCGA;ICGC	1.787	Gain
TK_Tec_BTK_Y	Q9UJV9	DDX41	Q06187	BTK	Y414	M421V	421	Missense	distal	7	no	3.037	2.982	PhosphoSitePlus	TCGA;ICGC;COSMIC	1.787	Down-regulation
TK_Tec_BTK_Y	Q9UJV9	DDX41	Q06187	BTK	Y414	E417K	417	Missense	distal	3	no	3.037	2.890	PhosphoSitePlus	TCGA;ICGC;COSMIC	1.787	Down-regulation
TK_Tec_BTK_Y	Q9UJV9	DDX41	Q06187	BTK	Y414	I409S	409	Missense	distal	-5	no	3.037	3.219	PhosphoSitePlus	TCGA;ICGC;COSMIC	1.787	Up-regulation
TK_Tec_BTK_Y	P42680	TEC	Q06187	BTK	Y206	E201K	201	Missense	distal	-5	no	3.171	3.280	PhosphoSitePlus	TCGA;ICGC;COSMIC	1.787	Up-regulation
TK_Tec_BTK_Y	P42680	TEC	Q06187	BTK	Y206	K211N	211	Missense	distal	5	no	3.171	3.240	PhosphoSitePlus	TCGA;ICGC;COSMIC	1.787	Up-regulation
TKL_IRAK_IRAK4_ST	Q96FA3	PELI1	Q9NWZ3	IRAK4	S70	S70G	70	Missense	central	0	yes	171.120	0.000	EPSD;PhosphoSitePlus	TCGA;ICGC	132.233	Loss
TKL_IRAK_IRAK4_ST	Q96FA3	PELI1	Q9NWZ3	IRAK4	S76	S78L	78	Missense	proximal	2	no	244.887	243.261	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	132.233	Down-regulation
TKL_IRAK_IRAK4_ST	Q96FA3	PELI1	Q9NWZ3	IRAK4	S76	Y79H	79	Missense	distal	3	no	244.887	232.381	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	132.233	Down-regulation
TKL_IRAK_IRAK4_ST	Q96FA3	PELI1	Q9NWZ3	IRAK4	S76	S70G	70	Missense	distal	-6	no	244.887	208.508	EPSD;PhosphoSitePlus	TCGA;ICGC	132.233	Down-regulation
TKL_IRAK_IRAK4_ST	Q96FA3	PELI1	Q9NWZ3	IRAK4	S78	S78L	78	Missense	central	0	yes	173.280	0.000	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	132.233	Loss
TKL_IRAK_IRAK4_ST	Q96FA3	PELI1	Q9NWZ3	IRAK4	S78	Y79H	79	Missense	proximal	1	no	173.280	161.785	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	132.233	Down-regulation
TKL_IRAK_IRAK4_ST	Q96FA3	PELI1	Q9NWZ3	IRAK4	S78	Q85H	85	Missense	distal	7	no	173.280	158.384	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	132.233	Down-regulation
TKL_IRAK_IRAK4_ST	Q96FA3	PELI1	Q9NWZ3	IRAK4	T80	V87L	87	Missense	distal	7	no	189.204	175.034	PhosphoSitePlus;EPSD	TCGA;ICGC;COSMIC	132.233	Down-regulation
TKL_IRAK_IRAK4_ST	Q96FA3	PELI1	Q9NWZ3	IRAK4	T80	S78L	78	Missense	proximal	-2	no	189.204	184.202	PhosphoSitePlus;EPSD	TCGA;ICGC;COSMIC	132.233	Down-regulation
TKL_IRAK_IRAK4_ST	Q96FA3	PELI1	Q9NWZ3	IRAK4	T80	Y79H	79	Missense	proximal	-1	no	189.204	189.987	PhosphoSitePlus;EPSD	TCGA;ICGC;COSMIC	132.233	Up-regulation
TKL_IRAK_IRAK4_ST	Q96FA3	PELI1	Q9NWZ3	IRAK4	T80	Q85H	85	Missense	distal	5	no	189.204	165.987	PhosphoSitePlus;EPSD	TCGA;ICGC;COSMIC	132.233	Down-regulation
TKL_IRAK_IRAK4_ST	Q96FA3	PELI1	Q9NWZ3	IRAK4	S82	V87L	87	Missense	distal	5	no	173.524	153.871	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	132.233	Down-regulation
TKL_IRAK_IRAK4_ST	Q96FA3	PELI1	Q9NWZ3	IRAK4	S82	V89F	89	Missense	distal	7	no	173.524	156.804	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	132.233	Down-regulation
TKL_IRAK_IRAK4_ST	Q96FA3	PELI1	Q9NWZ3	IRAK4	S82	S78L	78	Missense	distal	-4	no	173.524	148.612	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	132.233	Down-regulation
TKL_IRAK_IRAK4_ST	Q96FA3	PELI1	Q9NWZ3	IRAK4	S82	Y79H	79	Missense	distal	-3	no	173.524	175.400	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	132.233	Up-regulation
TKL_IRAK_IRAK4_ST	Q96FA3	PELI1	Q9NWZ3	IRAK4	S82	Q85H	85	Missense	distal	3	no	173.524	151.499	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	132.233	Down-regulation
TKL_IRAK_IRAK4_ST	Q96FA3	PELI1	Q9NWZ3	IRAK4	T86	V87L	87	Missense	proximal	1	no	195.317	181.309	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	132.233	Down-regulation
TKL_IRAK_IRAK4_ST	Q96FA3	PELI1	Q9NWZ3	IRAK4	T86	V89F	89	Missense	distal	3	no	195.317	168.449	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	132.233	Down-regulation
TKL_IRAK_IRAK4_ST	Q96FA3	PELI1	Q9NWZ3	IRAK4	T86	Y79H	79	Missense	distal	-7	no	195.317	183.589	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	132.233	Down-regulation
TKL_IRAK_IRAK4_ST	Q96FA3	PELI1	Q9NWZ3	IRAK4	T86	Q85H	85	Missense	proximal	-1	no	195.317	196.130	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	132.233	Up-regulation
TKL_IRAK_IRAK4_ST	Q96FA3	PELI1	Q9NWZ3	IRAK4	T288	P283H	283	Missense	distal	-5	no	161.359	154.381	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	132.233	Down-regulation
TKL_IRAK_IRAK4_ST	Q96FA3	PELI1	Q9NWZ3	IRAK4	S293	V299I	299	Missense	distal	6	no	169.983	135.755	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC;CCLE	132.233	Down-regulation
TKL_IRAK_IRAK4_ST	P51617	IRAK1	Q9NWZ3	IRAK4	S376	T381S	381	Missense	distal	5	no	184.823	174.760	EPSD;PhosphoSitePlus	TCGA;COSMIC	132.233	Down-regulation
TKL_IRAK_IRAK4_ST	P51617	IRAK1	Q9NWZ3	IRAK4	S376	S373R	373	Missense	distal	-3	no	184.823	184.193	EPSD;PhosphoSitePlus	TCGA;COSMIC	132.233	Down-regulation
TKL_IRAK_IRAK4_ST	P51617	IRAK1	Q9NWZ3	IRAK4	S376	S376R	376	Missense	central	0	yes	184.823	0.000	EPSD;PhosphoSitePlus	TCGA	132.233	Loss
TKL_IRAK_IRAK4_ST	P51617	IRAK1	Q9NWZ3	IRAK4	T381	S376R	376	Missense	distal	-5	no	170.123	171.231	EPSD	TCGA	132.233	Up-regulation
TKL_IRAK_IRAK4_ST	P51617	IRAK1	Q9NWZ3	IRAK4	T381	L388M	388	Missense	distal	7	no	170.123	178.135	EPSD	TCGA;COSMIC	132.233	Up-regulation
TKL_IRAK_IRAK4_ST	P51617	IRAK1	Q9NWZ3	IRAK4	T387	T381S	381	Missense	distal	-6	no	205.395	209.672	PhosphoSitePlus;EPSD	TCGA;COSMIC	132.233	Up-regulation
TKL_IRAK_IRAK4_ST	P51617	IRAK1	Q9NWZ3	IRAK4	T387	L391V	391	Missense	distal	4	no	205.395	217.019	PhosphoSitePlus;EPSD	TCGA	132.233	Up-regulation
TKL_IRAK_IRAK4_ST	P51617	IRAK1	Q9NWZ3	IRAK4	T387	L388M	388	Missense	proximal	1	no	205.395	217.921	PhosphoSitePlus;EPSD	TCGA;COSMIC	132.233	Up-regulation
TKL_IRAK_IRAK4_ST	Q9NWZ3	IRAK4	Q9NWZ3	IRAK4	T6	R12C	12	Missense	distal	6	no	240.049	178.056	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	132.233	Down-regulation
TKL_IRAK_IRAK4_ST	Q9NWZ3	IRAK4	Q9NWZ3	IRAK4	T6	C13F	13	Missense	distal	7	no	240.049	244.437	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	132.233	Up-regulation
TKL_IRAK_IRAK4_ST	Q9NWZ3	IRAK4	Q9NWZ3	IRAK4	S8	R12C	12	Missense	distal	4	no	283.097	261.180	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	132.233	Down-regulation
TKL_IRAK_IRAK4_ST	Q9NWZ3	IRAK4	Q9NWZ3	IRAK4	S8	C13F	13	Missense	distal	5	no	283.097	289.371	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	132.233	Up-regulation
TKL_IRAK_IRAK4_ST	Q9NWZ3	IRAK4	Q9NWZ3	IRAK4	S150	S144I	144	Missense	distal	-6	no	169.510	150.407	EPSD;PhosphoSitePlus	TCGA;COSMIC	132.233	Down-regulation
TKL_IRAK_IRAK4_ST	Q9NWZ3	IRAK4	Q9NWZ3	IRAK4	S151	S144I	144	Missense	distal	-7	no	174.237	160.128	EPSD;PhosphoSitePlus	TCGA;COSMIC	132.233	Down-regulation
TKL_IRAK_IRAK4_ST	Q9NWZ3	IRAK4	Q9NWZ3	IRAK4	T208	V205I	205	Missense	distal	-3	no	238.403	239.196	PhosphoSitePlus;EPSD	TCGA;CCLE	132.233	Up-regulation
TKL_IRAK_IRAK4_ST	Q9NWZ3	IRAK4	Q9NWZ3	IRAK4	T208	V205L	205	Missense	distal	-3	no	238.403	240.355	PhosphoSitePlus;EPSD	TCGA;COSMIC	132.233	Up-regulation
TKL_IRAK_IRAK4_ST	Q9NWZ3	IRAK4	Q9NWZ3	IRAK4	T209	V205I	205	Missense	distal	-4	no	179.147	149.243	EPSD;PhosphoSitePlus	TCGA;CCLE	132.233	Down-regulation
TKL_IRAK_IRAK4_ST	Q9NWZ3	IRAK4	Q9NWZ3	IRAK4	T209	V205L	205	Missense	distal	-4	no	179.147	144.109	EPSD;PhosphoSitePlus	TCGA;COSMIC	132.233	Down-regulation
TKL_IRAK_IRAK4_ST	Q9NWZ3	IRAK4	Q9NWZ3	IRAK4	T342	A335P	335	Missense	distal	-7	no	199.999	213.097	EPSD;PhosphoSitePlus	TCGA;COSMIC	132.233	Up-regulation
TKL_IRAK_IRAK4_ST	Q9NWZ3	IRAK4	Q9NWZ3	IRAK4	T342	I348T	348	Missense	distal	6	no	199.999	223.471	EPSD;PhosphoSitePlus	TCGA;COSMIC	132.233	Up-regulation
TKL_IRAK_IRAK4_ST	Q9NWZ3	IRAK4	Q9NWZ3	IRAK4	T345	I348T	348	Missense	distal	3	no	160.697	185.513	EPSD;PhosphoSitePlus	TCGA;COSMIC	132.233	Up-regulation
TKL_IRAK_IRAK4_ST	Q9NWZ3	IRAK4	Q9NWZ3	IRAK4	S346	I348T	348	Missense	proximal	2	no	196.241	207.175	EPSD;PhosphoSitePlus	TCGA;COSMIC	132.233	Up-regulation
TKL_IRAK_IRAK4_ST	Q9NWZ3	IRAK4	Q9NWZ3	IRAK4	T352	A359V	359	Missense	distal	7	no	150.820	161.067	EPSD;PhosphoSitePlus	TCGA;COSMIC	132.233	Up-regulation
TKL_IRAK_IRAK4_ST	Q9NWZ3	IRAK4	Q9NWZ3	IRAK4	T352	I348T	348	Missense	distal	-4	no	150.820	193.526	EPSD;PhosphoSitePlus	TCGA;COSMIC	132.233	Up-regulation
TKL_IRAK_IRAK4_ST	Q9NWZ3	IRAK4	Q9NWZ3	IRAK4	S423	M418I	418	Missense	distal	-5	no	140.113	132.890	EPSD	TCGA;COSMIC	132.233	Down-regulation
TKL_IRAK_IRAK4_ST	Q9NWZ3	IRAK4	Q9NWZ3	IRAK4	S423	V426I	426	Missense	distal	3	no	140.113	122.048	EPSD	TCGA;COSMIC	132.233	Loss
TKL_IRAK_IRAK4_ST	Q9NWZ3	IRAK4	Q9NWZ3	IRAK4	S423	K416N	416	Missense	distal	-7	no	140.113	131.183	EPSD	TCGA;COSMIC	132.233	Loss
TKL_IRAK_IRAK4_ST	P14598	NCF1	Q9NWZ3	IRAK4	T95	E96K	96	Missense	proximal	1	no	128.257	133.190	EPSD	TCGA;ICGC;COSMIC	132.233	Gain
TKL_IRAK_IRAK4_ST	P14598	NCF1	Q9NWZ3	IRAK4	T133	T129M	129	Missense	distal	-4	no	213.222	193.564	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	132.233	Down-regulation
TKL_IRAK_IRAK4_ST	P14598	NCF1	Q9NWZ3	IRAK4	T133	K135N	135	Missense	proximal	2	no	213.222	213.548	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	132.233	Up-regulation
TKL_IRAK_IRAK4_ST	P14598	NCF1	Q9NWZ3	IRAK4	T133	N131K	131	Missense	proximal	-2	no	213.222	212.458	EPSD;PhosphoSitePlus	TCGA	132.233	Down-regulation
TKL_IRAK_IRAK4_ST	P14598	NCF1	Q9NWZ3	IRAK4	T133	P128S	128	Missense	distal	-5	no	213.222	212.639	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	132.233	Down-regulation
TKL_IRAK_IRAK4_ST	P14598	NCF1	Q9NWZ3	IRAK4	T133	D130N	130	Missense	distal	-3	no	213.222	211.880	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	132.233	Down-regulation
TKL_IRAK_IRAK4_ST	P14598	NCF1	Q9NWZ3	IRAK4	T138	K135N	135	Missense	distal	-3	no	227.545	227.919	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	132.233	Up-regulation
TKL_IRAK_IRAK4_ST	P14598	NCF1	Q9NWZ3	IRAK4	T138	N131K	131	Missense	distal	-7	no	227.545	236.476	EPSD;PhosphoSitePlus	TCGA	132.233	Up-regulation
TKL_IRAK_IRAK4_ST	P14598	NCF1	Q9NWZ3	IRAK4	T153	T160M	160	Missense	distal	7	no	158.663	148.872	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	132.233	Down-regulation
TKL_IRAK_IRAK4_ST	P14598	NCF1	Q9NWZ3	IRAK4	S173	L177M	177	Missense	distal	4	no	148.443	156.645	EPSD	TCGA;ICGC	132.233	Up-regulation
TKL_IRAK_IRAK4_ST	P14598	NCF1	Q9NWZ3	IRAK4	S173	T179M	179	Missense	distal	6	no	148.443	126.220	EPSD	TCGA;ICGC;COSMIC	132.233	Loss
TKL_IRAK_IRAK4_ST	P14598	NCF1	Q9NWZ3	IRAK4	S173	S171P	171	Missense	proximal	-2	no	148.443	148.348	EPSD	TCGA;ICGC;COSMIC	132.233	Down-regulation
TKL_IRAK_IRAK4_ST	P14598	NCF1	Q9NWZ3	IRAK4	T179	L177M	177	Missense	proximal	-2	no	125.316	133.397	EPSD	TCGA;ICGC	132.233	Gain
TKL_IRAK_IRAK4_ST	P14598	NCF1	Q9NWZ3	IRAK4	S288	V287M	287	Missense	proximal	-1	no	186.376	186.866	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	132.233	Up-regulation
CK1_TTBK_TTBK1_ST	P10636	MAPT	Q5TCY1	TTBK1	S228	S232Y	232	Missense	distal	4	no	11.654	11.055	EPSD	TCGA;ICGC;COSMIC	7.699	Down-regulation
CK1_TTBK_TTBK1_ST	P10636	MAPT	Q5TCY1	TTBK1	S228	D223Y	223	Missense	distal	-5	no	11.654	11.542	EPSD	TCGA;ICGC;COSMIC	7.699	Down-regulation
CK1_TTBK_TTBK1_ST	P10636	MAPT	Q5TCY1	TTBK1	S228	S227F	227	Missense	proximal	-1	no	11.654	11.541	EPSD	TCGA;ICGC;COSMIC	7.699	Down-regulation
CK1_TTBK_TTBK1_ST	P10636	MAPT	Q5TCY1	TTBK1	S228	P234L	234	Missense	distal	6	no	11.654	11.475	EPSD	TCGA;ICGC;COSMIC	7.699	Down-regulation
CK1_TTBK_TTBK1_ST	P10636	MAPT	Q5TCY1	TTBK1	S238	S232Y	232	Missense	distal	-6	no	11.337	10.297	EPSD	TCGA;ICGC;COSMIC	7.699	Down-regulation
CK1_TTBK_TTBK1_ST	P10636	MAPT	Q5TCY1	TTBK1	S238	A240T	240	Missense	proximal	2	no	11.337	11.351	EPSD	TCGA;ICGC;COSMIC	7.699	Up-regulation
CK1_TTBK_TTBK1_ST	P10636	MAPT	Q5TCY1	TTBK1	S238	P234L	234	Missense	distal	-4	no	11.337	11.354	EPSD	TCGA;ICGC;COSMIC	7.699	Up-regulation
CK1_TTBK_TTBK1_ST	P10636	MAPT	Q5TCY1	TTBK1	S238	R244Q	244	Missense	distal	6	no	11.337	11.924	EPSD	TCGA;ICGC;COSMIC	7.699	Up-regulation
CK1_TTBK_TTBK1_ST	P10636	MAPT	Q5TCY1	TTBK1	S382	G387R	387	Missense	distal	5	no	9.123	9.546	EPSD	TCGA;COSMIC	7.699	Up-regulation
CK1_TTBK_TTBK1_ST	P10636	MAPT	Q5TCY1	TTBK1	S382	R377C	377	Missense	distal	-5	no	9.123	8.908	EPSD	TCGA;COSMIC	7.699	Down-regulation
CK1_TTBK_TTBK1_ST	P10636	MAPT	Q5TCY1	TTBK1	S411	P415L	415	Missense	distal	4	no	10.521	10.241	EPSD	TCGA;ICGC;COSMIC	7.699	Down-regulation
CK1_TTBK_TTBK1_ST	P10636	MAPT	Q5TCY1	TTBK1	S428	A430S	430	Missense	proximal	2	no	11.626	11.638	EPSD	TCGA;ICGC;COSMIC	7.699	Up-regulation
CK1_TTBK_TTBK1_ST	P10636	MAPT	Q5TCY1	TTBK1	S428	V431L	431	Missense	distal	3	no	11.626	11.805	EPSD	TCGA;ICGC;COSMIC	7.699	Up-regulation
CK1_TTBK_TTBK1_ST	P10636	MAPT	Q5TCY1	TTBK1	S428	A430V	430	Missense	proximal	2	no	11.626	11.605	EPSD	TCGA;ICGC;COSMIC	7.699	Down-regulation
TKL_MLK_ZAK_MAP3K20_ST	O96017	CHEK2	Q9NYL2	MAP3K20	T68	E70G	70	Missense	proximal	2	no	7.577	7.553	PhosphoSitePlus	TCGA	2.674	Down-regulation
CAMK_CAMKL_NuaK_NUAK1_ST	P38936	CDKN1A	O60285	NUAK1	T97	R94W	94	Missense	distal	-3	no	4.897	2.608	EPSD	TCGA;ICGC;COSMIC	4.034	Loss
CAMK_CAMKL_NuaK_NUAK1_ST	P38936	CDKN1A	O60285	NUAK1	T97	R93S	93	Missense	distal	-4	no	4.897	5.020	EPSD	TCGA;ICGC;COSMIC	4.034	Up-regulation
CAMK_CAMKL_NuaK_NUAK1_ST	P38936	CDKN1A	O60285	NUAK1	T97	R94P	94	Missense	distal	-3	no	4.897	3.364	EPSD	TCGA;ICGC;COSMIC	4.034	Loss
CAMK_CAMKL_NuaK_NUAK1_ST	P38936	CDKN1A	O60285	NUAK1	T97	P95S	95	Missense	proximal	-2	no	4.897	4.795	EPSD	TCGA;ICGC;COSMIC	4.034	Down-regulation
CAMK_CAMKL_NuaK_NUAK1_ST	P38936	CDKN1A	O60285	NUAK1	S98	R94W	94	Missense	distal	-4	no	4.313	4.329	EPSD	TCGA;ICGC;COSMIC	4.034	Up-regulation
CAMK_CAMKL_NuaK_NUAK1_ST	P38936	CDKN1A	O60285	NUAK1	S98	R93S	93	Missense	distal	-5	no	4.313	4.268	EPSD	TCGA;ICGC;COSMIC	4.034	Down-regulation
CAMK_CAMKL_NuaK_NUAK1_ST	P38936	CDKN1A	O60285	NUAK1	S98	R94P	94	Missense	distal	-4	no	4.313	4.308	EPSD	TCGA;ICGC;COSMIC	4.034	Down-regulation
CAMK_CAMKL_NuaK_NUAK1_ST	P38936	CDKN1A	O60285	NUAK1	S98	P95S	95	Missense	distal	-3	no	4.313	3.818	EPSD	TCGA;ICGC;COSMIC	4.034	Loss
CAMK_CAMKL_NuaK_NUAK1_ST	P38936	CDKN1A	O60285	NUAK1	S130	D136H	136	Missense	distal	6	no	4.669	4.655	EPSD	TCGA;ICGC;COSMIC	4.034	Down-regulation
CAMK_CAMKL_NuaK_NUAK1_ST	P38936	CDKN1A	O60285	NUAK1	S130	G132C	132	Missense	proximal	2	no	4.669	4.452	EPSD	TCGA;ICGC;COSMIC	4.034	Down-regulation
CAMK_CAMKL_NuaK_NUAK1_ST	P38936	CDKN1A	O60285	NUAK1	S130	E128K	128	Missense	proximal	-2	no	4.669	4.933	EPSD	TCGA;ICGC;COSMIC	4.034	Up-regulation
CAMK_CAMKL_NuaK_NUAK1_ST	P38936	CDKN1A	O60285	NUAK1	S130	G135A	135	Missense	distal	5	no	4.669	4.455	EPSD	TCGA	4.034	Down-regulation
CAMK_CAMKL_NuaK_NUAK1_ST	P38936	CDKN1A	O60285	NUAK1	S137	D136H	136	Missense	proximal	-1	no	5.630	5.115	EPSD	TCGA;ICGC;COSMIC	4.034	Down-regulation
CAMK_CAMKL_NuaK_NUAK1_ST	P38936	CDKN1A	O60285	NUAK1	S137	G132C	132	Missense	distal	-5	no	5.630	5.708	EPSD	TCGA;ICGC;COSMIC	4.034	Up-regulation
CAMK_CAMKL_NuaK_NUAK1_ST	P38936	CDKN1A	O60285	NUAK1	S137	G135A	135	Missense	proximal	-2	no	5.630	5.815	EPSD	TCGA	4.034	Up-regulation
CAMK_CAMKL_NuaK_NUAK1_ST	P38936	CDKN1A	O60285	NUAK1	S137	R142W	142	Missense	distal	5	no	5.630	5.613	EPSD	TCGA;ICGC;COSMIC;GDSC;CCLE	4.034	Down-regulation
CAMK_CAMKL_NuaK_NUAK1_ST	P38936	CDKN1A	O60285	NUAK1	S146	S153C	153	Missense	distal	7	no	5.858	5.665	PhosphoSitePlus	TCGA;ICGC;COSMIC	4.034	Down-regulation
CAMK_CAMKL_NuaK_NUAK1_ST	P38936	CDKN1A	O60285	NUAK1	S146	D149H	149	Missense	distal	3	no	5.858	5.850	PhosphoSitePlus	TCGA;ICGC;COSMIC	4.034	Down-regulation
CAMK_CAMKL_NuaK_NUAK1_ST	P38936	CDKN1A	O60285	NUAK1	S146	R142W	142	Missense	distal	-4	no	5.858	5.874	PhosphoSitePlus	TCGA;ICGC;COSMIC;GDSC;CCLE	4.034	Up-regulation
CAMK_CAMKL_NuaK_NUAK1_ST	P38936	CDKN1A	O60285	NUAK1	S153	S153C	153	Missense	central	0	yes	5.516	0.000	EPSD	TCGA;ICGC;COSMIC	4.034	Loss
CAMK_CAMKL_NuaK_NUAK1_ST	P38936	CDKN1A	O60285	NUAK1	S153	R155H	155	Missense	proximal	2	no	5.516	5.321	EPSD	TCGA;ICGC;COSMIC;CCLE	4.034	Down-regulation
CAMK_CAMKL_NuaK_NUAK1_ST	P38936	CDKN1A	O60285	NUAK1	S153	D149H	149	Missense	distal	-4	no	5.516	5.468	EPSD	TCGA;ICGC;COSMIC	4.034	Down-regulation
CAMK_CAMKL_NuaK_NUAK1_ST	P10636	MAPT	O60285	NUAK1	S214	P212L	212	Missense	proximal	-2	no	5.065	4.105	EPSD	TCGA;ICGC;COSMIC	4.034	Down-regulation
CAMK_CAMKL_NuaK_NUAK1_ST	P10636	MAPT	O60285	NUAK1	S214	E220K	220	Missense	distal	6	no	5.065	5.022	EPSD	TCGA;ICGC;COSMIC	4.034	Down-regulation
CAMK_CAMKL_NuaK_NUAK1_ST	P10636	MAPT	O60285	NUAK1	S228	S232Y	232	Missense	distal	4	no	3.770	4.329	EPSD	TCGA;ICGC;COSMIC	4.034	Gain
CAMK_CAMKL_NuaK_NUAK1_ST	P10636	MAPT	O60285	NUAK1	S228	S227F	227	Missense	proximal	-1	no	3.770	4.240	EPSD	TCGA;ICGC;COSMIC	4.034	Gain
CAMK_CAMKL_NuaK_NUAK1_ST	P10636	MAPT	O60285	NUAK1	S369	Q373R	373	Missense	distal	4	no	4.000	4.060	EPSD	TCGA;ICGC;COSMIC	4.034	Gain
CAMK_CAMKL_NuaK_NUAK1_ST	P10636	MAPT	O60285	NUAK1	S382	G387R	387	Missense	distal	5	no	4.317	4.224	EPSD	TCGA;COSMIC	4.034	Down-regulation
CAMK_CAMKL_NuaK_NUAK1_ST	P10636	MAPT	O60285	NUAK1	S382	R377C	377	Missense	distal	-5	no	4.317	4.422	EPSD	TCGA;COSMIC	4.034	Up-regulation
CAMK_CAMKL_NuaK_NUAK1_ST	P10636	MAPT	O60285	NUAK1	S388	G387R	387	Missense	proximal	-1	no	5.031	4.898	EPSD	TCGA;COSMIC	4.034	Down-regulation
CAMK_CAMKL_NuaK_NUAK1_ST	P10636	MAPT	O60285	NUAK1	S438	P436T	436	Missense	proximal	-2	no	4.184	3.557	EPSD	TCGA;ICGC;COSMIC	4.034	Loss
CAMK_CAMKL_NuaK_NUAK1_ST	P10636	MAPT	O60285	NUAK1	S438	P436L	436	Missense	proximal	-2	no	4.184	3.224	EPSD	TCGA;ICGC;COSMIC	4.034	Loss
CAMK_CAMKL_NuaK_NUAK1_ST	P10636	MAPT	O60285	NUAK1	S438	K440E	440	Missense	proximal	2	no	4.184	4.533	EPSD	TCGA;ICGC;COSMIC	4.034	Up-regulation
CAMK_CAMKL_NuaK_NUAK1_ST	P10636	MAPT	O60285	NUAK1	S438	S443F	443	Missense	distal	5	no	4.184	4.141	EPSD	TCGA;ICGC;COSMIC	4.034	Down-regulation
CAMK_CAMKL_NuaK_NUAK1_ST	P10636	MAPT	O60285	NUAK1	S438	V431L	431	Missense	distal	-7	no	4.184	4.324	EPSD	TCGA;ICGC;COSMIC	4.034	Up-regulation
CAMK_CAMKL_NuaK_NUAK1_ST	P10636	MAPT	O60285	NUAK1	S438	S444F	444	Missense	distal	6	no	4.184	4.156	EPSD	TCGA;ICGC	4.034	Down-regulation
CAMK_CAMKL_NuaK_NUAK1_ST	P10636	MAPT	O60285	NUAK1	S451	E456K	456	Missense	distal	5	no	4.528	4.788	EPSD	TCGA;ICGC;COSMIC	4.034	Up-regulation
CAMK_CAMKL_NuaK_NUAK1_ST	P10636	MAPT	O60285	NUAK1	S451	S452C	452	Missense	proximal	1	no	4.528	4.558	EPSD	TCGA;ICGC;COSMIC	4.034	Up-regulation
CAMK_CAMKL_NuaK_NUAK1_ST	P10636	MAPT	O60285	NUAK1	S451	S444F	444	Missense	distal	-7	no	4.528	4.504	EPSD	TCGA;ICGC	4.034	Down-regulation
CAMK_CAMKL_NuaK_NUAK1_ST	P10636	MAPT	O60285	NUAK1	S451	S452Y	452	Missense	proximal	1	no	4.528	4.542	EPSD	TCGA;ICGC;COSMIC	4.034	Up-regulation
CAMK_CAMKL_NuaK_NUAK1_ST	P10636	MAPT	O60285	NUAK1	T470	R472Q	472	Missense	proximal	2	no	4.777	4.708	EPSD	TCGA	4.034	Down-regulation
CAMK_CAMKL_NuaK_NUAK1_ST	P10636	MAPT	O60285	NUAK1	T470	R472W	472	Missense	proximal	2	no	4.777	4.718	EPSD	TCGA;COSMIC	4.034	Down-regulation
CAMK_CAMKL_NuaK_NUAK1_ST	O14974	PPP1R12A	O60285	NUAK1	S313	K315N	315	Missense	proximal	2	no	3.882	4.095	EPSD	TCGA;ICGC;COSMIC	4.034	Gain
CAMK_CAMKL_NuaK_NUAK1_ST	O14974	PPP1R12A	O60285	NUAK1	S356	D360V	360	Missense	distal	4	no	3.331	4.285	EPSD	TCGA;ICGC;COSMIC	4.034	Gain
CAMK_CAMKL_NuaK_NUAK1_ST	O14974	PPP1R12A	O60285	NUAK1	S432	W436C	436	Missense	distal	4	no	4.000	4.631	EPSD	TCGA;ICGC;COSMIC	4.034	Gain
CAMK_CAMKL_NuaK_NUAK1_ST	O14974	PPP1R12A	O60285	NUAK1	S445	T443M	443	Missense	proximal	-2	no	9.000	9.276	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	4.034	Up-regulation
CAMK_CAMKL_NuaK_NUAK1_ST	O14974	PPP1R12A	O60285	NUAK1	S472	R475K	475	Missense	distal	3	no	9.804	9.869	PhosphoSitePlus;EPSD	TCGA;ICGC;COSMIC	4.034	Up-regulation
CAMK_CAMKL_NuaK_NUAK1_ST	O14974	PPP1R12A	O60285	NUAK1	S477	R475K	475	Missense	proximal	-2	no	3.842	4.316	EPSD	TCGA;ICGC;COSMIC	4.034	Gain
CAMK_CAMKL_NuaK_NUAK1_ST	O14974	PPP1R12A	O60285	NUAK1	S554	R557K	557	Missense	distal	3	no	5.509	5.574	EPSD	TCGA;ICGC;COSMIC	4.034	Up-regulation
CAMK_CAMKL_NuaK_NUAK1_ST	O14974	PPP1R12A	O60285	NUAK1	S572	S565C	565	Missense	distal	-7	no	4.106	3.932	EPSD	TCGA;ICGC;COSMIC;CCLE	4.034	Loss
CAMK_CAMKL_NuaK_NUAK1_ST	O14974	PPP1R12A	O60285	NUAK1	S572	P568S	568	Missense	distal	-4	no	4.106	4.234	EPSD	TCGA;ICGC	4.034	Up-regulation
CAMK_CAMKL_NuaK_NUAK1_ST	O14974	PPP1R12A	O60285	NUAK1	S602	K595N	595	Missense	distal	-7	no	3.569	4.061	EPSD	TCGA;ICGC	4.034	Gain
CAMK_CAMKL_NuaK_NUAK1_ST	O14974	PPP1R12A	O60285	NUAK1	S610	A615V	615	Missense	distal	5	no	4.065	3.977	EPSD	TCGA;ICGC;COSMIC	4.034	Loss
CAMK_CAMKL_NuaK_NUAK1_ST	O14974	PPP1R12A	O60285	NUAK1	S610	T609A	609	Missense	proximal	-1	no	4.065	4.201	EPSD	TCGA;ICGC;COSMIC	4.034	Up-regulation
CAMK_CAMKL_NuaK_NUAK1_ST	O14974	PPP1R12A	O60285	NUAK1	S668	R667I	667	Missense	proximal	-1	no	4.184	3.912	EPSD	TCGA;ICGC;COSMIC	4.034	Loss
CAMK_CAMKL_NuaK_NUAK1_ST	O14974	PPP1R12A	O60285	NUAK1	S716	R715C	715	Missense	proximal	-1	no	4.110	4.095	EPSD	TCGA;ICGC;COSMIC	4.034	Down-regulation
CAMK_CAMKL_NuaK_NUAK1_ST	O14974	PPP1R12A	O60285	NUAK1	S802	T807P	807	Missense	distal	5	no	4.224	3.976	EPSD	TCGA;ICGC;COSMIC	4.034	Loss
CAMK_CAMKL_NuaK_NUAK1_ST	O14974	PPP1R12A	O60285	NUAK1	S802	T807I	807	Missense	distal	5	no	4.224	4.292	EPSD	TCGA;ICGC;COSMIC	4.034	Up-regulation
CAMK_CAMKL_NuaK_NUAK1_ST	O14974	PPP1R12A	O60285	NUAK1	S862	E866K	866	Missense	distal	4	no	4.293	4.354	EPSD	TCGA;ICGC;COSMIC	4.034	Up-regulation
CAMK_CAMKL_NuaK_NUAK1_ST	O14974	PPP1R12A	O60285	NUAK1	S903	R907C	907	Missense	distal	4	no	3.446	4.222	EPSD	TCGA;ICGC;COSMIC	4.034	Gain
CAMK_CAMKL_NuaK_NUAK1_ST	O14974	PPP1R12A	O60285	NUAK1	S910	S903A	903	Missense	distal	-7	no	9.475	9.388	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	4.034	Down-regulation
CAMK_CAMKL_NuaK_NUAK1_ST	O14974	PPP1R12A	O60285	NUAK1	S910	R907C	907	Missense	distal	-3	no	9.475	7.797	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	4.034	Down-regulation
CAMK_CAMKL_NuaK_NUAK1_ST	O14974	PPP1R12A	O60285	NUAK1	S921	P919S	919	Missense	proximal	-2	no	4.692	4.590	EPSD	TCGA	4.034	Down-regulation
CAMK_CAMKL_NuaK_NUAK1_ST	O14974	PPP1R12A	O60285	NUAK1	S929	S929L	929	Missense	central	0	yes	5.157	0.000	EPSD	TCGA;ICGC;COSMIC	4.034	Loss
CAMK_CAMKL_NuaK_NUAK1_ST	O14974	PPP1R12A	O60285	NUAK1	S929	K933R	933	Missense	distal	4	no	5.157	5.198	EPSD	TCGA;ICGC;COSMIC	4.034	Up-regulation
CAMK_CAMKL_NuaK_NUAK1_ST	P55212	CASP6	O60285	NUAK1	S3	S3W	3	Missense	central	0	yes	4.590	0.000	EPSD	TCGA;ICGC;COSMIC	4.034	Loss
CAMK_CAMKL_NuaK_NUAK1_ST	P55212	CASP6	O60285	NUAK1	S3	R8P	8	Missense	distal	5	no	4.590	4.302	EPSD	TCGA;ICGC;COSMIC	4.034	Down-regulation
CAMK_CAMKL_NuaK_NUAK1_ST	P55212	CASP6	O60285	NUAK1	S257	R259C	259	Missense	proximal	2	no	9.653	9.546	PhosphoSitePlus	TCGA;COSMIC	4.034	Down-regulation
CAMK_CAMKL_NuaK_NUAK1_ST	P04637	TP53	O60285	NUAK1	S106	R110L	110	Missense	distal	4	no	2.927	4.193	EPSD	TCGA;ICGC;COSMIC;GDSC;CCLE	4.034	Gain
CAMK_CAMKL_NuaK_NUAK1_ST	P04637	TP53	O60285	NUAK1	S183	E180K	180	Missense	distal	-3	no	3.021	4.970	EPSD	TCGA;ICGC;COSMIC;CCLE	4.034	Gain
CAMK_CAMKL_NuaK_NUAK1_ST	O95835	LATS1	O60285	NUAK1	S21	R28W	28	Missense	distal	7	no	4.364	4.285	EPSD	TCGA	4.034	Down-regulation
CAMK_CAMKL_NuaK_NUAK1_ST	O95835	LATS1	O60285	NUAK1	S21	R28Q	28	Missense	distal	7	no	4.364	4.328	EPSD	TCGA;ICGC;COSMIC	4.034	Down-regulation
CAMK_CAMKL_NuaK_NUAK1_ST	O95835	LATS1	O60285	NUAK1	S21	V25F	25	Missense	distal	4	no	4.364	4.329	EPSD	TCGA;ICGC;COSMIC	4.034	Down-regulation
CAMK_CAMKL_NuaK_NUAK1_ST	O95835	LATS1	O60285	NUAK1	S177	Q176L	176	Missense	proximal	-1	no	5.066	5.418	EPSD	TCGA;ICGC;COSMIC	4.034	Up-regulation
CAMK_CAMKL_NuaK_NUAK1_ST	O95835	LATS1	O60285	NUAK1	S177	R174H	174	Missense	distal	-3	no	5.066	2.426	EPSD	TCGA;ICGC;COSMIC	4.034	Loss
CAMK_CAMKL_NuaK_NUAK1_ST	O95835	LATS1	O60285	NUAK1	S204	Q208L	208	Missense	distal	4	no	4.356	5.682	EPSD	TCGA;ICGC;COSMIC	4.034	Up-regulation
CAMK_CAMKL_NuaK_NUAK1_ST	O95835	LATS1	O60285	NUAK1	S216	G217E	217	Missense	proximal	1	no	4.999	5.049	EPSD	TCGA;ICGC;COSMIC	4.034	Up-regulation
CAMK_CAMKL_NuaK_NUAK1_ST	O95835	LATS1	O60285	NUAK1	S216	G217V	217	Missense	proximal	1	no	4.999	5.090	EPSD	TCGA;ICGC;COSMIC	4.034	Up-regulation
CAMK_CAMKL_NuaK_NUAK1_ST	O95835	LATS1	O60285	NUAK1	S216	A222V	222	Missense	distal	6	no	4.999	5.024	EPSD	TCGA;ICGC;COSMIC	4.034	Up-regulation
CAMK_CAMKL_NuaK_NUAK1_ST	O95835	LATS1	O60285	NUAK1	S218	A222V	222	Missense	distal	4	no	3.688	4.461	EPSD	TCGA;ICGC;COSMIC	4.034	Gain
CAMK_CAMKL_NuaK_NUAK1_ST	O95835	LATS1	O60285	NUAK1	S278	Y277C	277	Missense	proximal	-1	no	3.783	4.053	EPSD	TCGA;ICGC;COSMIC	4.034	Gain
CAMK_CAMKL_NuaK_NUAK1_ST	O95835	LATS1	O60285	NUAK1	S387	S387F	387	Missense	central	0	yes	4.540	0.000	EPSD	TCGA;ICGC;COSMIC	4.034	Loss
CAMK_CAMKL_NuaK_NUAK1_ST	O95835	LATS1	O60285	NUAK1	S387	S387Y	387	Missense	central	0	yes	4.540	0.000	EPSD	TCGA;ICGC	4.034	Loss
CAMK_CAMKL_NuaK_NUAK1_ST	O95835	LATS1	O60285	NUAK1	S387	A380S	380	Missense	distal	-7	no	4.540	4.626	EPSD	TCGA;ICGC	4.034	Up-regulation
CAMK_CAMKL_NuaK_NUAK1_ST	O95835	LATS1	O60285	NUAK1	S408	V411A	411	Missense	distal	3	no	4.127	4.160	EPSD	TCGA;ICGC;COSMIC	4.034	Up-regulation
CAMK_CAMKL_NuaK_NUAK1_ST	O95835	LATS1	O60285	NUAK1	S464	V460M	460	Missense	distal	-4	no	9.586	9.677	PhosphoSitePlus	TCGA;ICGC;COSMIC	4.034	Up-regulation
CAMK_CAMKL_NuaK_NUAK1_ST	O95835	LATS1	O60285	NUAK1	S464	N471S	471	Missense	distal	7	no	9.586	9.635	PhosphoSitePlus	TCGA;ICGC;COSMIC;CCLE	4.034	Up-regulation
CAMK_CAMKL_NuaK_NUAK1_ST	O95835	LATS1	O60285	NUAK1	S464	N463S	463	Missense	proximal	-1	no	9.586	9.194	PhosphoSitePlus	TCGA;ICGC;COSMIC	4.034	Down-regulation
CAMK_CAMKL_NuaK_NUAK1_ST	O95835	LATS1	O60285	NUAK1	S464	S464F	464	Missense	central	0	yes	9.586	0.000	PhosphoSitePlus	TCGA;ICGC;COSMIC	4.034	Loss
CAMK_CAMKL_NuaK_NUAK1_ST	O95835	LATS1	O60285	NUAK1	S464	S464Y	464	Missense	central	0	yes	9.586	0.000	PhosphoSitePlus	TCGA;ICGC;COSMIC	4.034	Loss
CAMK_CAMKL_NuaK_NUAK1_ST	O95835	LATS1	O60285	NUAK1	S633	R630H	630	Missense	distal	-3	no	4.312	1.672	EPSD	TCGA;ICGC	4.034	Loss
CAMK_CAMKL_NuaK_NUAK1_ST	O95835	LATS1	O60285	NUAK1	S633	R627W	627	Missense	distal	-6	no	4.312	4.224	EPSD	TCGA;ICGC;COSMIC	4.034	Down-regulation
CAMK_CAMKL_NuaK_NUAK1_ST	O95835	LATS1	O60285	NUAK1	S633	R627S	627	Missense	distal	-6	no	4.312	4.239	EPSD	TCGA;ICGC;COSMIC	4.034	Down-regulation
CAMK_CAMKL_NuaK_NUAK1_ST	O95835	LATS1	O60285	NUAK1	S633	R626Q	626	Missense	distal	-7	no	4.312	4.159	EPSD	TCGA;ICGC;COSMIC	4.034	Down-regulation
CAMK_CAMKL_NuaK_NUAK1_ST	O95835	LATS1	O60285	NUAK1	S872	D871Y	871	Missense	proximal	-1	no	4.576	4.247	EPSD	TCGA;ICGC;COSMIC	4.034	Down-regulation
Other_ULK_ULK_ULK2_ST	O15027	SEC16A	Q8IYT8	ULK2	S1236	R1231Q	1231	Missense	distal	-5	no	3.523	3.626	EPSD	TCGA;ICGC;COSMIC	3.097	Up-regulation
Other_ULK_ULK_ULK2_ST	O15027	SEC16A	Q8IYT8	ULK2	S1903	P1901S	1901	Missense	proximal	-2	no	3.218	3.278	EPSD	TCGA;ICGC;COSMIC	3.097	Up-regulation
Other_ULK_ULK_ULK2_ST	A2RUS2	DENND3	Q8IYT8	ULK2	S368	T361I	361	Missense	distal	-7	no	3.130	3.146	EPSD	TCGA;ICGC	3.097	Up-regulation
Other_ULK_ULK_ULK2_ST	A2RUS2	DENND3	Q8IYT8	ULK2	S368	N375K	375	Missense	distal	7	no	3.130	3.013	EPSD	TCGA;ICGC;COSMIC	3.097	Loss
Other_ULK_ULK_ULK2_ST	A2RUS2	DENND3	Q8IYT8	ULK2	S368	K374T	374	Missense	distal	6	no	3.130	3.131	EPSD	TCGA;ICGC;COSMIC	3.097	Up-regulation
Other_ULK_ULK_ULK2_ST	A2RUS2	DENND3	Q8IYT8	ULK2	S472	M469V	469	Missense	distal	-3	no	9.056	8.358	PhosphoSitePlus;EPSD	TCGA;ICGC;COSMIC	3.097	Down-regulation
Other_ULK_ULK_ULK2_ST	A2RUS2	DENND3	Q8IYT8	ULK2	S472	R467M	467	Missense	distal	-5	no	9.056	9.134	PhosphoSitePlus;EPSD	TCGA;ICGC	3.097	Up-regulation
Other_ULK_ULK_ULK2_ST	A2RUS2	DENND3	Q8IYT8	ULK2	S472	V471I	471	Missense	proximal	-1	no	9.056	8.962	PhosphoSitePlus;EPSD	TCGA;ICGC;COSMIC	3.097	Down-regulation
Other_ULK_ULK_ULK2_ST	A2RUS2	DENND3	Q8IYT8	ULK2	S472	D478N	478	Missense	distal	6	no	9.056	9.046	PhosphoSitePlus;EPSD	TCGA;ICGC;COSMIC	3.097	Down-regulation
Other_ULK_ULK_ULK2_ST	A2RUS2	DENND3	Q8IYT8	ULK2	S490	S490L	490	Missense	central	0	yes	9.018	0.000	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	3.097	Loss
Other_ULK_ULK_ULK2_ST	A2RUS2	DENND3	Q8IYT8	ULK2	S490	T494M	494	Missense	distal	4	no	9.018	8.973	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	3.097	Down-regulation
Other_ULK_ULK_ULK2_ST	A2RUS2	DENND3	Q8IYT8	ULK2	S490	A497T	497	Missense	distal	7	no	9.018	8.977	EPSD;PhosphoSitePlus	TCGA;ICGC;COSMIC	3.097	Down-regulation
Other_ULK_ULK_ULK2_ST	A2RUS2	DENND3	Q8IYT8	ULK2	S503	A497T	497	Missense	distal	-6	no	3.204	3.071	EPSD	TCGA;ICGC;COSMIC	3.097	Loss
Other_ULK_ULK_ULK2_ST	A2RUS2	DENND3	Q8IYT8	ULK2	S503	G501D	501	Missense	proximal	-2	no	3.204	3.207	EPSD	TCGA;ICGC;COSMIC	3.097	Up-regulation
Other_PEK_HRI_EIF2AK1_ST	P05198	EIF2S1	Q9BQI3	EIF2AK1	S219	E221G	221	Missense	proximal	2	no	2.612	2.560	EPSD	ICGC;COSMIC	2.464	Down-regulation
Other_PEK_HRI_EIF2AK1_ST	P05198	EIF2S1	Q9BQI3	EIF2AK1	S219	G215V	215	Missense	distal	-4	no	2.612	2.613	EPSD	ICGC;COSMIC	2.464	Up-regulation
AGC_PKC_PKCd_PRKCD_ST	P18433	PTPRA	Q05655	PRKCD	S193	V200L	200	Missense	distal	7	no	7.813	7.818	EPSD	ICGC	7.604	Up-regulation
AGC_PKC_PKCd_PRKCD_ST	P18433	PTPRA	Q05655	PRKCD	S542	E536D	536	Missense	distal	-6	no	9.289	9.274	EPSD	ICGC	7.604	Down-regulation
AGC_PKC_PKCd_PRKCD_ST	P18433	PTPRA	Q05655	PRKCD	T672	S670I	670	Missense	proximal	-2	no	8.225	6.349	EPSD	ICGC	7.604	Loss
AGC_PKC_PKCd_PRKCD_ST	P18433	PTPRA	Q05655	PRKCD	S766	D759N	759	Missense	distal	-7	no	8.609	8.606	EPSD	ICGC	7.604	Down-regulation
AGC_PKC_PKCd_PRKCD_ST	P10415	BCL2	Q05655	PRKCD	S24	E29D	29	Missense	distal	5	no	12.548	12.531	EPSD	ICGC;COSMIC	7.604	Down-regulation
AGC_PKC_PKCd_PRKCD_ST	P10415	BCL2	Q05655	PRKCD	S24	H20Q	20	Missense	distal	-4	no	12.548	12.571	EPSD	ICGC;COSMIC	7.604	Up-regulation
AGC_PKC_PKCd_PRKCD_ST	P10415	BCL2	Q05655	PRKCD	S24	D31G	31	Missense	distal	7	no	12.548	12.545	EPSD	ICGC;COSMIC	7.604	Down-regulation
AGC_PKC_PKCd_PRKCD_ST	P10415	BCL2	Q05655	PRKCD	S24	D31E	31	Missense	distal	7	no	12.548	12.545	EPSD	ICGC;COSMIC	7.604	Down-regulation
AGC_PKC_PKCd_PRKCD_ST	P10415	BCL2	Q05655	PRKCD	S24	D31H	31	Missense	distal	7	no	12.548	12.567	EPSD	ICGC;COSMIC;GDSC	7.604	Up-regulation
AGC_PKC_PKCd_PRKCD_ST	P10415	BCL2	Q05655	PRKCD	S24	K22R	22	Missense	proximal	-2	no	12.548	13.793	EPSD	ICGC;COSMIC	7.604	Up-regulation
AGC_PKC_PKCd_PRKCD_ST	P10415	BCL2	Q05655	PRKCD	S24	E29K	29	Missense	distal	5	no	12.548	12.986	EPSD	ICGC;COSMIC	7.604	Up-regulation
AGC_PKC_PKCd_PRKCD_ST	P10415	BCL2	Q05655	PRKCD	S24	Y21S	21	Missense	distal	-3	no	12.548	13.851	EPSD	ICGC;COSMIC	7.604	Up-regulation
AGC_PKC_PKCd_PRKCD_ST	P10415	BCL2	Q05655	PRKCD	S216	F212L	212	Missense	distal	-4	no	9.483	9.513	EPSD	ICGC;COSMIC	7.604	Up-regulation
AGC_PKC_PKCd_PRKCD_ST	P10415	BCL2	Q05655	PRKCD	S216	T219N	219	Missense	distal	3	no	9.483	9.354	EPSD	ICGC	7.604	Down-regulation
AGC_PKC_PKCd_PRKCD_ST	P61978	HNRNPK	Q05655	PRKCD	T177	Q175K	175	Missense	proximal	-2	no	5.114	9.303	EPSD	ICGC;COSMIC	7.604	Gain
AGC_PKC_PKCd_PRKCD_ST	P61978	HNRNPK	Q05655	PRKCD	S276	R271C	271	Missense	distal	-5	no	9.475	8.998	EPSD	ICGC	7.604	Down-regulation
AGC_PKC_PKCd_PRKCD_ST	P61978	HNRNPK	Q05655	PRKCD	S302	A304T	304	Missense	proximal	2	no	7.752	6.721	PhosphoSitePlus	ICGC;COSMIC	7.604	Loss
AGC_PKC_PKCd_PRKCD_ST	P61978	HNRNPK	Q05655	PRKCD	S417	I423V	423	Missense	distal	6	no	8.790	8.794	EPSD	ICGC;COSMIC	7.604	Up-regulation
AGC_PKC_PKCd_PRKCD_ST	P61978	HNRNPK	Q05655	PRKCD	S459	G460A	460	Missense	proximal	1	no	11.179	11.206	EPSD	ICGC;COSMIC	7.604	Up-regulation
AGC_PKC_PKCd_PRKCD_ST	P61978	HNRNPK	Q05655	PRKCD	S459	Y458H	458	Missense	proximal	-1	no	11.179	11.254	EPSD	ICGC	7.604	Up-regulation
AGC_PKC_PKCd_PRKCD_ST	Q9UQ13	SHOC2	Q05655	PRKCD	S57	A60S	60	Missense	distal	3	no	9.753	9.819	EPSD	ICGC;COSMIC	7.604	Up-regulation
AGC_PKC_PKCd_PRKCD_ST	Q9UQ13	SHOC2	Q05655	PRKCD	S57	Q61K	61	Missense	distal	4	no	9.753	10.333	EPSD	ICGC;COSMIC	7.604	Up-regulation
AGC_PKC_PKCd_PRKCD_ST	Q9UQ13	SHOC2	Q05655	PRKCD	S58	Q61K	61	Missense	distal	3	no	6.756	7.840	EPSD	ICGC;COSMIC	7.604	Gain
AGC_PKC_PKCd_PRKCD_ST	Q9UQ13	SHOC2	Q05655	PRKCD	S85	A78S	78	Missense	distal	-7	no	11.553	11.560	EPSD	ICGC	7.604	Up-regulation
AGC_PKC_PKCd_PRKCD_ST	Q9UQ13	SHOC2	Q05655	PRKCD	S85	K84Q	84	Missense	proximal	-1	no	11.553	11.423	EPSD	ICGC;COSMIC	7.604	Down-regulation
AGC_PKC_PKCd_PRKCD_ST	Q9UQ13	SHOC2	Q05655	PRKCD	S86	K84Q	84	Missense	proximal	-2	no	11.454	7.265	EPSD	ICGC;COSMIC	7.604	Loss
AGC_PKC_PKCd_PRKCD_ST	Q9UQ13	SHOC2	Q05655	PRKCD	S221	L217V	217	Missense	distal	-4	no	10.060	10.067	EPSD	ICGC;COSMIC	7.604	Up-regulation
AGC_PKC_PKCd_PRKCD_ST	Q9UQ13	SHOC2	Q05655	PRKCD	S221	L214F	214	Missense	distal	-7	no	10.060	10.061	EPSD	ICGC	7.604	Up-regulation
AGC_PKC_PKCd_PRKCD_ST	P53004	BLVRA	Q05655	PRKCD	S21	R28W	28	Missense	distal	7	no	15.400	15.234	EPSD;PhosphoSitePlus	ICGC;COSMIC;GDSC;CCLE	7.604	Down-regulation
AGC_PKC_PKCd_PRKCD_ST	P53004	BLVRA	Q05655	PRKCD	S21	G15D	15	Missense	distal	-6	no	15.400	15.362	EPSD;PhosphoSitePlus	ICGC;COSMIC	7.604	Down-regulation
AGC_PKC_PKCd_PRKCD_ST	P53004	BLVRA	Q05655	PRKCD	S21	G15V	15	Missense	distal	-6	no	15.400	15.451	EPSD;PhosphoSitePlus	ICGC	7.604	Up-regulation
AGC_PKC_PKCd_PRKCD_ST	P53004	BLVRA	Q05655	PRKCD	S230	S235T	235	Missense	distal	5	no	8.620	8.524	EPSD;PhosphoSitePlus	ICGC;COSMIC	7.604	Down-regulation
AGC_PKC_PKCd_PRKCD_ST	P35611	ADD1	Q05655	PRKCD	S59	A66S	66	Missense	distal	7	no	10.835	10.861	EPSD	ICGC	7.604	Up-regulation
AGC_PKC_PKCd_PRKCD_ST	P35611	ADD1	Q05655	PRKCD	S59	M52I	52	Missense	distal	-7	no	10.835	10.832	EPSD	ICGC	7.604	Down-regulation
AGC_PKC_PKCd_PRKCD_ST	P35611	ADD1	Q05655	PRKCD	S59	V58A	58	Missense	proximal	-1	no	10.835	10.884	EPSD	ICGC;COSMIC	7.604	Up-regulation
AGC_PKC_PKCd_PRKCD_ST	P35611	ADD1	Q05655	PRKCD	S59	M60K	60	Missense	proximal	1	no	10.835	11.040	EPSD	ICGC;COSMIC	7.604	Up-regulation
AGC_PKC_PKCd_PRKCD_ST	P35611	ADD1	Q05655	PRKCD	S133	S133F	133	Missense	central	0	yes	7.860	0.000	EPSD	ICGC	7.604	Loss
AGC_PKC_PKCd_PRKCD_ST	P35611	ADD1	Q05655	PRKCD	S353	P359L	359	Missense	distal	6	no	8.812	8.788	EPSD	ICGC;COSMIC	7.604	Down-regulation
AGC_PKC_PKCd_PRKCD_ST	P35611	ADD1	Q05655	PRKCD	S353	G357V	357	Missense	distal	4	no	8.812	8.788	EPSD	ICGC	7.604	Down-regulation
AGC_PKC_PKCd_PRKCD_ST	P35611	ADD1	Q05655	PRKCD	S355	P359L	359	Missense	distal	4	no	7.607	7.403	EPSD	ICGC;COSMIC	7.604	Loss
AGC_PKC_PKCd_PRKCD_ST	P35611	ADD1	Q05655	PRKCD	S355	G357V	357	Missense	proximal	2	no	7.607	7.568	EPSD	ICGC	7.604	Loss
AGC_PKC_PKCd_PRKCD_ST	P35611	ADD1	Q05655	PRKCD	S355	P359T	359	Missense	distal	4	no	7.607	7.533	EPSD	ICGC;COSMIC	7.604	Loss
AGC_PKC_PKCd_PRKCD_ST	P35611	ADD1	Q05655	PRKCD	S404	K403T	403	Missense	proximal	-1	no	12.122	11.992	EPSD	ICGC	7.604	Down-regulation
AGC_PKC_PKCd_PRKCD_ST	P35611	ADD1	Q05655	PRKCD	S404	S408I	408	Missense	distal	4	no	12.122	11.834	EPSD	ICGC;COSMIC	7.604	Down-regulation
AGC_PKC_PKCd_PRKCD_ST	P35611	ADD1	Q05655	PRKCD	S408	K403T	403	Missense	distal	-5	no	11.745	11.471	EPSD	ICGC	7.604	Down-regulation
AGC_PKC_PKCd_PRKCD_ST	P35611	ADD1	Q05655	PRKCD	S408	S408I	408	Missense	central	0	yes	11.745	0.000	EPSD	ICGC;COSMIC	7.604	Loss
AGC_PKC_PKCd_PRKCD_ST	P35611	ADD1	Q05655	PRKCD	S436	P432T	432	Missense	distal	-4	no	7.747	7.777	EPSD	ICGC;COSMIC	7.604	Up-regulation
AGC_PKC_PKCd_PRKCD_ST	P35611	ADD1	Q05655	PRKCD	S481	D476N	476	Missense	distal	-5	no	8.617	8.593	EPSD	ICGC;COSMIC	7.604	Down-regulation
AGC_PKC_PKCd_PRKCD_ST	P35611	ADD1	Q05655	PRKCD	S669	P667H	667	Missense	proximal	-2	no	8.801	8.289	EPSD	ICGC;COSMIC	7.604	Down-regulation
AGC_PKC_PKCd_PRKCD_ST	P35611	ADD1	Q05655	PRKCD	S716	R723C	723	Missense	distal	7	no	14.867	14.729	EPSD	ICGC;COSMIC	7.604	Down-regulation
AGC_PKC_PKCd_PRKCD_ST	P35611	ADD1	Q05655	PRKCD	S716	S714F	714	Missense	proximal	-2	no	14.867	14.343	EPSD	ICGC;COSMIC	7.604	Down-regulation
AGC_PKC_PKCd_PRKCD_ST	P35611	ADD1	Q05655	PRKCD	S716	P711S	711	Missense	distal	-5	no	14.867	14.875	EPSD	ICGC;COSMIC	7.604	Up-regulation
AGC_PKC_PKCd_PRKCD_ST	P35611	ADD1	Q05655	PRKCD	S716	P715L	715	Missense	proximal	-1	no	14.867	14.791	EPSD	ICGC;COSMIC	7.604	Down-regulation
AGC_PKC_PKCd_PRKCD_ST	P35611	ADD1	Q05655	PRKCD	S726	R723C	723	Missense	distal	-3	no	10.284	4.965	PhosphoSitePlus	ICGC;COSMIC	7.604	Loss
AGC_PKC_PKCd_PRKCD_ST	P35611	ADD1	Q05655	PRKCD	S726	P725L	725	Missense	proximal	-1	no	10.284	10.208	PhosphoSitePlus	ICGC;COSMIC	7.604	Down-regulation
AGC_PKC_PKCd_PRKCD_ST	P35611	ADD1	Q05655	PRKCD	S731	P725L	725	Missense	distal	-6	no	13.559	13.728	EPSD	ICGC;COSMIC	7.604	Up-regulation
AGC_PKC_PKCd_PRKCD_ST	P14598	NCF1	Q05655	PRKCD	T45	E46K	46	Missense	proximal	1	no	9.067	9.228	EPSD	ICGC	7.604	Up-regulation
AGC_PKC_PKCd_PRKCD_ST	Q16206	ENOX2	Q05655	PRKCD	S240	V244M	244	Missense	distal	4	no	9.670	9.680	EPSD	ICGC;COSMIC	7.604	Up-regulation
AGC_PKC_PKCd_PRKCD_ST	Q16206	ENOX2	Q05655	PRKCD	S240	P238Q	238	Missense	proximal	-2	no	9.670	8.699	EPSD	ICGC	7.604	Down-regulation
AGC_PKC_PKCd_PRKCD_ST	Q16206	ENOX2	Q05655	PRKCD	S531	S526G	526	Missense	distal	-5	no	8.851	8.713	EPSD	ICGC;COSMIC	7.604	Down-regulation
AGC_PKC_PKCd_PRKCD_ST	Q16206	ENOX2	Q05655	PRKCD	S531	S526R	526	Missense	distal	-5	no	8.851	9.126	EPSD	ICGC;COSMIC	7.604	Up-regulation
AGC_PKC_PKCd_PRKCD_ST	Q16206	ENOX2	Q05655	PRKCD	S531	R533S	533	Missense	proximal	2	no	8.851	2.788	EPSD	ICGC	7.604	Loss
AGC_PKC_PKCd_PRKCD_ST	Q16206	ENOX2	Q05655	PRKCD	S531	N525K	525	Missense	distal	-6	no	8.851	8.401	EPSD	ICGC	7.604	Down-regulation
AGC_PKC_PKCd_PRKCD_ST	Q16206	ENOX2	Q05655	PRKCD	S531	A535E	535	Missense	distal	4	no	8.851	8.786	EPSD	ICGC	7.604	Down-regulation
AGC_PKC_PKCd_PRKCD_ST	Q16206	ENOX2	Q05655	PRKCD	S531	A535T	535	Missense	distal	4	no	8.851	8.883	EPSD	ICGC;COSMIC	7.604	Up-regulation
AGC_PKC_PKCd_PRKCD_ST	Q16206	ENOX2	Q05655	PRKCD	S531	P528H	528	Missense	distal	-3	no	8.851	8.840	EPSD	ICGC;COSMIC	7.604	Down-regulation
AGC_PKC_PKCd_PRKCD_ST	P19429	TNNI3	Q05655	PRKCD	S23	R27S	27	Missense	distal	4	no	15.118	14.648	EPSD;PhosphoSitePlus	ICGC	7.604	Down-regulation
AGC_PKC_PKCd_PRKCD_ST	P19429	TNNI3	Q05655	PRKCD	S23	R21S	21	Missense	proximal	-2	no	15.118	10.270	EPSD;PhosphoSitePlus	ICGC	7.604	Down-regulation
AGC_PKC_PKCd_PRKCD_ST	P19429	TNNI3	Q05655	PRKCD	S23	S24F	24	Missense	proximal	1	no	15.118	15.069	EPSD;PhosphoSitePlus	ICGC;COSMIC	7.604	Down-regulation
AGC_PKC_PKCd_PRKCD_ST	P19429	TNNI3	Q05655	PRKCD	S23	R21L	21	Missense	proximal	-2	no	15.118	8.985	EPSD;PhosphoSitePlus	ICGC;COSMIC	7.604	Down-regulation
AGC_PKC_PKCd_PRKCD_ST	P19429	TNNI3	Q05655	PRKCD	S24	R27S	27	Missense	distal	3	no	14.127	13.270	EPSD;PhosphoSitePlus	ICGC	7.604	Down-regulation
AGC_PKC_PKCd_PRKCD_ST	P19429	TNNI3	Q05655	PRKCD	S24	R21S	21	Missense	distal	-3	no	14.127	9.552	EPSD;PhosphoSitePlus	ICGC	7.604	Down-regulation
AGC_PKC_PKCd_PRKCD_ST	P19429	TNNI3	Q05655	PRKCD	S24	S24F	24	Missense	central	0	yes	14.127	0.000	EPSD;PhosphoSitePlus	ICGC;COSMIC	7.604	Loss
AGC_PKC_PKCd_PRKCD_ST	P19429	TNNI3	Q05655	PRKCD	S24	R21L	21	Missense	distal	-3	no	14.127	8.940	EPSD;PhosphoSitePlus	ICGC;COSMIC	7.604	Down-regulation
AGC_PKC_PKCd_PRKCD_ST	P19429	TNNI3	Q05655	PRKCD	S39	P33Q	33	Missense	distal	-6	no	10.376	10.401	EPSD	ICGC	7.604	Up-regulation
AGC_PKC_PKCd_PRKCD_ST	P19429	TNNI3	Q05655	PRKCD	T143	R145W	145	Missense	proximal	2	no	18.627	11.954	PhosphoSitePlus;EPSD	ICGC;COSMIC;GDSC;CCLE	7.604	Down-regulation
AGC_PKC_PKCd_PRKCD_ST	P19429	TNNI3	Q05655	PRKCD	S150	R145W	145	Missense	distal	-5	no	8.191	7.647	EPSD	ICGC;COSMIC;GDSC;CCLE	7.604	Down-regulation
AGC_PKC_PKCd_PRKCD_ST	P19429	TNNI3	Q05655	PRKCD	T181	E184K	184	Missense	distal	3	no	9.017	10.198	EPSD	ICGC;COSMIC	7.604	Up-regulation
AGC_PKC_PKCd_PRKCD_ST	O76090	BEST1	Q05655	PRKCD	S16	R19C	19	Missense	distal	3	no	9.342	8.067	EPSD	ICGC;COSMIC	7.604	Down-regulation
AGC_PKC_PKCd_PRKCD_ST	O76090	BEST1	Q05655	PRKCD	S16	R13C	13	Missense	distal	-3	no	9.342	4.022	EPSD	ICGC;COSMIC	7.604	Loss
AGC_PKC_PKCd_PRKCD_ST	O76090	BEST1	Q05655	PRKCD	S16	L21M	21	Missense	distal	5	no	9.342	9.273	EPSD	ICGC;COSMIC	7.604	Down-regulation
AGC_PKC_PKCd_PRKCD_ST	O76090	BEST1	Q05655	PRKCD	S16	R13H	13	Missense	distal	-3	no	9.342	5.087	EPSD	ICGC;COSMIC;GDSC;CCLE	7.604	Loss
AGC_PKC_PKCd_PRKCD_ST	O76090	BEST1	Q05655	PRKCD	S358	T363A	363	Missense	distal	5	no	13.384	13.345	PhosphoSitePlus	ICGC;COSMIC	7.604	Down-regulation
AGC_PKC_PKCd_PRKCD_ST	O76090	BEST1	Q05655	PRKCD	S358	A357V	357	Missense	proximal	-1	no	13.384	13.335	PhosphoSitePlus	ICGC	7.604	Down-regulation
AGC_PKC_PKCd_PRKCD_ST	O76090	BEST1	Q05655	PRKCD	S358	M360I	360	Missense	proximal	2	no	13.384	12.580	PhosphoSitePlus	ICGC	7.604	Down-regulation
AGC_PKC_PKCd_PRKCD_ST	O76090	BEST1	Q05655	PRKCD	T536	N540S	540	Missense	distal	4	no	8.369	8.553	EPSD	ICGC;COSMIC	7.604	Up-regulation
AGC_PKC_PKCd_PRKCD_ST	O76090	BEST1	Q05655	PRKCD	T536	D543Y	543	Missense	distal	7	no	8.369	8.338	EPSD	ICGC	7.604	Down-regulation
AGC_PKC_PKCd_PRKCD_ST	Q9UBS0	RPS6KB2	Q05655	PRKCD	S24	E22K	22	Missense	proximal	-2	no	4.092	9.073	EPSD	ICGC;COSMIC	7.604	Gain
AGC_PKC_PKCd_PRKCD_ST	Q9UBS0	RPS6KB2	Q05655	PRKCD	S410	F404L	404	Missense	distal	-6	no	13.029	13.069	EPSD	ICGC	7.604	Up-regulation
AGC_PKC_PKCd_PRKCD_ST	Q9UBS0	RPS6KB2	Q05655	PRKCD	S416	V422I	422	Missense	distal	6	no	9.315	9.311	EPSD	ICGC;COSMIC;CCLE	7.604	Down-regulation
AGC_PKC_PKCd_PRKCD_ST	Q9UBS0	RPS6KB2	Q05655	PRKCD	S416	A420V	420	Missense	distal	4	no	9.315	9.160	EPSD	ICGC;COSMIC	7.604	Down-regulation
AGC_PKC_PKCd_PRKCD_ST	Q9UBS0	RPS6KB2	Q05655	PRKCD	S436	R434W	434	Missense	proximal	-2	no	7.834	1.580	EPSD	ICGC;COSMIC	7.604	Loss
AGC_PKC_PKCd_PRKCD_ST	Q9UBS0	RPS6KB2	Q05655	PRKCD	S436	S438N	438	Missense	proximal	2	no	7.834	7.346	EPSD	ICGC;COSMIC	7.604	Loss
AGC_PKC_PKCd_PRKCD_ST	Q9UBS0	RPS6KB2	Q05655	PRKCD	S436	E441V	441	Missense	distal	5	no	7.834	7.725	EPSD	ICGC	7.604	Down-regulation
AGC_PKC_PKCd_PRKCD_ST	Q9UBS0	RPS6KB2	Q05655	PRKCD	S436	S436I	436	Missense	central	0	yes	7.834	0.000	EPSD	ICGC	7.604	Loss
AGC_PKC_PKCd_PRKCD_ST	Q9UBS0	RPS6KB2	Q05655	PRKCD	S436	P437S	437	Missense	proximal	1	no	7.834	7.814	EPSD	ICGC	7.604	Down-regulation
AGC_PKC_PKCd_PRKCD_ST	Q9UBS0	RPS6KB2	Q05655	PRKCD	S436	P429H	429	Missense	distal	-7	no	7.834	7.829	EPSD	ICGC;COSMIC	7.604	Down-regulation
AGC_PKC_PKCd_PRKCD_ST	Q9H257	CARD9	Q05655	PRKCD	T95	R101C	101	Missense	distal	6	no	12.906	12.830	EPSD	ICGC	7.604	Down-regulation
AGC_PKC_PKCd_PRKCD_ST	Q9H257	CARD9	Q05655	PRKCD	T95	T95K	95	Missense	central	0	yes	12.906	0.000	EPSD	ICGC;COSMIC	7.604	Loss
AGC_PKC_PKCd_PRKCD_ST	Q9H257	CARD9	Q05655	PRKCD	T95	P88Q	88	Missense	distal	-7	no	12.906	12.902	EPSD	ICGC;COSMIC	7.604	Down-regulation
AGC_PKC_PKCd_PRKCD_ST	Q9H257	CARD9	Q05655	PRKCD	T231	A237T	237	Missense	distal	6	no	16.196	16.207	PhosphoSitePlus	ICGC;COSMIC	7.604	Up-regulation
AGC_PKC_PKCd_PRKCD_ST	Q9H257	CARD9	Q05655	PRKCD	S303	T300N	300	Missense	distal	-3	no	9.149	9.101	EPSD	ICGC	7.604	Down-regulation
AGC_PKC_PKCd_PRKCD_ST	Q9H257	CARD9	Q05655	PRKCD	S303	F302L	302	Missense	proximal	-1	no	9.149	9.139	EPSD	ICGC;COSMIC	7.604	Down-regulation
AGC_PKC_PKCd_PRKCD_ST	Q9H257	CARD9	Q05655	PRKCD	S431	D426N	426	Missense	distal	-5	no	10.159	10.136	EPSD	ICGC	7.604	Down-regulation
AGC_PKC_PKCd_PRKCD_ST	P05107	ITGB2	Q05655	PRKCD	S490	S496R	496	Missense	distal	6	no	7.721	7.754	EPSD	ICGC	7.604	Up-regulation
AGC_PKC_PKCd_PRKCD_ST	P05107	ITGB2	Q05655	PRKCD	S490	S489R	489	Missense	proximal	-1	no	7.721	7.795	EPSD	ICGC	7.604	Up-regulation
AGC_PKC_PKCd_PRKCD_ST	P05107	ITGB2	Q05655	PRKCD	S490	G487D	487	Missense	distal	-3	no	7.721	7.890	EPSD	ICGC	7.604	Up-regulation
AGC_PKC_PKCd_PRKCD_ST	P05107	ITGB2	Q05655	PRKCD	S496	S496R	496	Missense	central	0	yes	8.090	0.000	EPSD	ICGC	7.604	Loss
AGC_PKC_PKCd_PRKCD_ST	P05107	ITGB2	Q05655	PRKCD	S496	S489R	489	Missense	distal	-7	no	8.090	8.102	EPSD	ICGC	7.604	Up-regulation
AGC_PKC_PKCd_PRKCD_ST	Q05655	PRKCD	Q05655	PRKCD	T38	G41W	41	Missense	distal	3	no	8.523	8.237	EPSD	ICGC;COSMIC	7.604	Down-regulation
AGC_PKC_PKCd_PRKCD_ST	Q05655	PRKCD	Q05655	PRKCD	S130	R132C	132	Missense	proximal	2	no	13.856	6.977	EPSD	ICGC;COSMIC	7.604	Loss
AGC_PKC_PKCd_PRKCD_ST	Q05655	PRKCD	Q05655	PRKCD	S130	A137S	137	Missense	distal	7	no	13.856	13.882	EPSD	ICGC	7.604	Up-regulation
AGC_PKC_PKCd_PRKCD_ST	Q05655	PRKCD	Q05655	PRKCD	S130	D124G	124	Missense	distal	-6	no	13.856	13.894	EPSD	ICGC	7.604	Up-regulation
AGC_PKC_PKCd_PRKCD_ST	Q05655	PRKCD	Q05655	PRKCD	S299	Q296H	296	Missense	distal	-3	no	13.252	14.155	EPSD;PhosphoSitePlus	ICGC;COSMIC	7.604	Up-regulation
AGC_PKC_PKCd_PRKCD_ST	Q05655	PRKCD	Q05655	PRKCD	S302	Q296H	296	Missense	distal	-6	no	9.128	9.127	EPSD;PhosphoSitePlus	ICGC;COSMIC	7.604	Down-regulation
AGC_PKC_PKCd_PRKCD_ST	Q05655	PRKCD	Q05655	PRKCD	S359	G361R	361	Missense	proximal	2	no	7.425	13.757	EPSD	ICGC;COSMIC	7.604	Gain
AGC_PKC_PKCd_PRKCD_ST	Q05655	PRKCD	Q05655	PRKCD	S559	S559P	559	Missense	central	0	yes	8.200	0.000	EPSD	ICGC;COSMIC	7.604	Loss
AGC_PKC_PKCd_PRKCD_ST	Q05655	PRKCD	Q05655	PRKCD	S559	V562A	562	Missense	distal	3	no	8.200	8.433	EPSD	ICGC	7.604	Up-regulation
AGC_PKC_PKCd_PRKCD_ST	Q05655	PRKCD	Q05655	PRKCD	S559	D554N	554	Missense	distal	-5	no	8.200	8.177	EPSD	ICGC	7.604	Down-regulation
AGC_PKC_PKCd_PRKCD_ST	Q05655	PRKCD	Q05655	PRKCD	S645	E640K	640	Missense	distal	-5	no	8.728	9.085	EPSD;PhosphoSitePlus	ICGC;COSMIC	7.604	Up-regulation
AGC_PKC_PKCd_PRKCD_ST	Q05655	PRKCD	Q05655	PRKCD	S645	R643H	643	Missense	proximal	-2	no	8.728	3.752	EPSD;PhosphoSitePlus	ICGC;COSMIC	7.604	Loss
AGC_PKC_PKCd_PRKCD_ST	Q05655	PRKCD	Q05655	PRKCD	S645	R643C	643	Missense	proximal	-2	no	8.728	2.733	EPSD;PhosphoSitePlus	ICGC;COSMIC	7.604	Loss
AGC_PKC_PKCd_PRKCD_ST	Q05655	PRKCD	Q05655	PRKCD	S645	D648N	648	Missense	distal	3	no	8.728	8.703	EPSD;PhosphoSitePlus	ICGC;COSMIC	7.604	Down-regulation
AGC_PKC_PKCd_PRKCD_ST	P13796	LCP1	Q05655	PRKCD	T89	A87V	87	Missense	proximal	-2	no	7.876	7.244	EPSD	ICGC	7.604	Loss
AGC_PKC_PKCd_PRKCD_ST	Q9HBA0	TRPV4	Q05655	PRKCD	S134	A139V	139	Missense	distal	5	no	9.176	9.055	EPSD	ICGC;COSMIC	7.604	Down-regulation
AGC_PKC_PKCd_PRKCD_ST	Q9HBA0	TRPV4	Q05655	PRKCD	S134	S134R	134	Missense	central	0	yes	9.176	0.000	EPSD	ICGC	7.604	Loss
AGC_PKC_PKCd_PRKCD_ST	Q9HBA0	TRPV4	Q05655	PRKCD	S134	P135H	135	Missense	proximal	1	no	9.176	9.116	EPSD	ICGC;COSMIC	7.604	Down-regulation
AGC_PKC_PKCd_PRKCD_ST	Q9HBA0	TRPV4	Q05655	PRKCD	S134	I128T	128	Missense	distal	-6	no	9.176	8.948	EPSD	ICGC;COSMIC	7.604	Down-regulation
AGC_PKC_PKCd_PRKCD_ST	Q9HBA0	TRPV4	Q05655	PRKCD	S189	G191E	191	Missense	proximal	2	no	7.627	7.027	EPSD;PhosphoSitePlus	ICGC;COSMIC	7.604	Loss
AGC_PKC_PKCd_PRKCD_ST	Q13501	SQSTM1	Q05655	PRKCD	S24	R21H	21	Missense	distal	-3	no	13.318	9.063	EPSD	ICGC;GDSC;CCLE	7.604	Down-regulation
AGC_PKC_PKCd_PRKCD_ST	Q13501	SQSTM1	Q05655	PRKCD	S24	R18L	18	Missense	distal	-6	no	13.318	13.764	EPSD	ICGC	7.604	Up-regulation
AGC_PKC_PKCd_PRKCD_ST	Q13501	SQSTM1	Q05655	PRKCD	S24	P29S	29	Missense	distal	5	no	13.318	13.286	EPSD	ICGC;COSMIC	7.604	Down-regulation
AGC_PKC_PKCd_PRKCD_ST	Q13501	SQSTM1	Q05655	PRKCD	S207	N205S	205	Missense	proximal	-2	no	7.141	8.267	EPSD	ICGC;COSMIC	7.604	Gain
AGC_PKC_PKCd_PRKCD_ST	Q13501	SQSTM1	Q05655	PRKCD	S284	S284L	284	Missense	central	0	yes	8.808	0.000	EPSD	ICGC;COSMIC	7.604	Loss
AGC_PKC_PKCd_PRKCD_ST	P05787	KRT8	Q05655	PRKCD	S21	R23C	23	Missense	proximal	2	no	17.641	10.763	EPSD	ICGC;COSMIC;GDSC	7.604	Down-regulation
AGC_PKC_PKCd_PRKCD_ST	P05787	KRT8	Q05655	PRKCD	S34	S36W	36	Missense	proximal	2	no	8.274	7.665	EPSD	ICGC	7.604	Down-regulation
AGC_PKC_PKCd_PRKCD_ST	P05787	KRT8	Q05655	PRKCD	S34	S37C	37	Missense	distal	3	no	8.274	7.857	EPSD	ICGC;COSMIC	7.604	Down-regulation
AGC_PKC_PKCd_PRKCD_ST	P05787	KRT8	Q05655	PRKCD	S253	N250K	250	Missense	distal	-3	no	3.587	7.691	EPSD	ICGC;COSMIC	7.604	Gain
AGC_PKC_PKCd_PRKCD_ST	P04406	GAPDH	Q05655	PRKCD	S25	I30L	30	Missense	distal	5	no	9.327	9.470	EPSD	ICGC;COSMIC	7.604	Up-regulation
AGC_PKC_PKCd_PRKCD_ST	P04406	GAPDH	Q05655	PRKCD	S25	A32S	32	Missense	distal	7	no	9.327	9.353	EPSD	ICGC	7.604	Up-regulation
AGC_PKC_PKCd_PRKCD_ST	P04406	GAPDH	Q05655	PRKCD	S192	L195P	195	Missense	distal	3	no	7.437	7.718	EPSD	ICGC;COSMIC	7.604	Gain
AGC_PKC_PKCd_PRKCD_ST	Q02297	NRG1	Q05655	PRKCD	S444	S450F	450	Missense	distal	6	no	7.895	7.868	EPSD	ICGC;COSMIC	7.604	Down-regulation
AGC_PKC_PKCd_PRKCD_ST	P51398	DAP3	Q05655	PRKCD	S31	R29H	29	Missense	proximal	-2	no	9.607	4.631	PhosphoSitePlus;EPSD	ICGC	7.604	Loss
AGC_PKC_PKCd_PRKCD_ST	P51398	DAP3	Q05655	PRKCD	S44	P45S	45	Missense	proximal	1	no	8.907	8.887	EPSD	ICGC	7.604	Down-regulation
AGC_PKC_PKCd_PRKCD_ST	P51398	DAP3	Q05655	PRKCD	S215	S220I	220	Missense	distal	5	no	11.775	11.442	EPSD	ICGC;COSMIC	7.604	Down-regulation
AGC_PKC_PKCd_PRKCD_ST	P51398	DAP3	Q05655	PRKCD	S215	E214G	214	Missense	proximal	-1	no	11.775	11.778	EPSD	ICGC;COSMIC	7.604	Up-regulation
AGC_PKC_PKCd_PRKCD_ST	P51398	DAP3	Q05655	PRKCD	T216	S220I	220	Missense	distal	4	no	10.214	9.926	EPSD	ICGC;COSMIC	7.604	Down-regulation
AGC_PKC_PKCd_PRKCD_ST	P51398	DAP3	Q05655	PRKCD	T216	E214G	214	Missense	proximal	-2	no	10.214	10.676	EPSD	ICGC;COSMIC	7.604	Up-regulation
AGC_PKC_PKCd_PRKCD_ST	P51398	DAP3	Q05655	PRKCD	S251	S252C	252	Missense	proximal	1	no	10.259	10.140	EPSD	ICGC;COSMIC	7.604	Down-regulation
AGC_PKC_PKCd_PRKCD_ST	P51398	DAP3	Q05655	PRKCD	T273	G270R	270	Missense	distal	-3	no	11.344	16.552	EPSD	ICGC;COSMIC	7.604	Up-regulation
AGC_PKC_PKCd_PRKCD_ST	P51398	DAP3	Q05655	PRKCD	T273	N266Y	266	Missense	distal	-7	no	11.344	11.340	EPSD	ICGC;COSMIC	7.604	Down-regulation
AGC_PKC_PKCd_PRKCD_ST	P42224	STAT1	Q05655	PRKCD	S604	F603L	603	Missense	proximal	-1	no	9.193	9.183	EPSD	ICGC;COSMIC	7.604	Down-regulation
AGC_PKC_PKCd_PRKCD_ST	P42224	STAT1	Q05655	PRKCD	S604	R602W	602	Missense	proximal	-2	no	9.193	2.939	EPSD	ICGC;GDSC	7.604	Loss
AGC_PKC_PKCd_PRKCD_ST	P42224	STAT1	Q05655	PRKCD	S604	R602L	602	Missense	proximal	-2	no	9.193	3.060	EPSD	ICGC;COSMIC	7.604	Loss
AGC_PKC_PKCd_PRKCD_ST	P42224	STAT1	Q05655	PRKCD	S606	F603L	603	Missense	distal	-3	no	9.555	8.892	EPSD	ICGC;COSMIC	7.604	Down-regulation
AGC_PKC_PKCd_PRKCD_ST	P42224	STAT1	Q05655	PRKCD	S606	R602W	602	Missense	distal	-4	no	9.555	10.086	EPSD	ICGC;GDSC	7.604	Up-regulation
AGC_PKC_PKCd_PRKCD_ST	P42224	STAT1	Q05655	PRKCD	S606	R602L	602	Missense	distal	-4	no	9.555	9.947	EPSD	ICGC;COSMIC	7.604	Up-regulation
AGC_PKC_PKCd_PRKCD_ST	P62753	RPS6	Q05655	PRKCD	S235	A229S	229	Missense	distal	-6	no	16.067	15.949	PhosphoSitePlus;EPSD	ICGC;COSMIC	7.604	Down-regulation
AGC_PKC_PKCd_PRKCD_ST	P62753	RPS6	Q05655	PRKCD	S235	A229V	229	Missense	distal	-6	no	16.067	16.192	PhosphoSitePlus;EPSD	ICGC;COSMIC;GDSC;CCLE	7.604	Up-regulation
AGC_PKC_PKCd_PRKCD_ST	P62753	RPS6	Q05655	PRKCD	S236	A229S	229	Missense	distal	-7	no	14.320	14.326	EPSD;PhosphoSitePlus	ICGC;COSMIC	7.604	Up-regulation
AGC_PKC_PKCd_PRKCD_ST	P62753	RPS6	Q05655	PRKCD	S236	A229V	229	Missense	distal	-7	no	14.320	14.314	EPSD;PhosphoSitePlus	ICGC;COSMIC;GDSC;CCLE	7.604	Down-regulation
AGC_PKC_PKCd_PRKCD_ST	Q14247	CTTN	Q05655	PRKCD	S109	V115L	115	Missense	distal	6	no	7.847	7.852	EPSD	ICGC	7.604	Up-regulation
AGC_PKC_PKCd_PRKCD_ST	Q14247	CTTN	Q05655	PRKCD	S109	Q114H	114	Missense	distal	5	no	7.847	7.828	EPSD	ICGC	7.604	Down-regulation
AGC_PKC_PKCd_PRKCD_ST	Q14247	CTTN	Q05655	PRKCD	S117	V115L	115	Missense	proximal	-2	no	7.793	7.102	EPSD	ICGC	7.604	Loss
AGC_PKC_PKCd_PRKCD_ST	Q14247	CTTN	Q05655	PRKCD	S117	G120C	120	Missense	distal	3	no	7.793	7.655	EPSD	ICGC	7.604	Down-regulation
AGC_PKC_PKCd_PRKCD_ST	Q14247	CTTN	Q05655	PRKCD	S117	Q114H	114	Missense	distal	-3	no	7.793	8.696	EPSD	ICGC	7.604	Up-regulation
AGC_PKC_PKCd_PRKCD_ST	Q14247	CTTN	Q05655	PRKCD	S150	K144N	144	Missense	distal	-6	no	13.265	13.715	EPSD	ICGC	7.604	Up-regulation
AGC_PKC_PKCd_PRKCD_ST	Q14247	CTTN	Q05655	PRKCD	S187	G180V	180	Missense	distal	-7	no	13.982	13.980	EPSD	ICGC;COSMIC	7.604	Down-regulation
AGC_PKC_PKCd_PRKCD_ST	Q14247	CTTN	Q05655	PRKCD	S187	S187P	187	Missense	central	0	yes	13.982	0.000	EPSD	ICGC	7.604	Loss
AGC_PKC_PKCd_PRKCD_ST	Q14247	CTTN	Q05655	PRKCD	S224	G231R	231	Missense	distal	7	no	12.196	12.305	EPSD	ICGC	7.604	Up-regulation
AGC_PKC_PKCd_PRKCD_ST	Q14247	CTTN	Q05655	PRKCD	S277	A283V	283	Missense	distal	6	no	9.333	9.316	EPSD	ICGC;COSMIC	7.604	Down-regulation
AGC_PKC_PKCd_PRKCD_ST	Q14247	CTTN	Q05655	PRKCD	S277	G274V	274	Missense	distal	-3	no	9.333	9.741	EPSD	ICGC;COSMIC	7.604	Up-regulation
AGC_PKC_PKCd_PRKCD_ST	Q14247	CTTN	Q05655	PRKCD	S277	V275F	275	Missense	proximal	-2	no	9.333	9.403	EPSD	ICGC;COSMIC	7.604	Up-regulation
AGC_PKC_PKCd_PRKCD_ST	Q14247	CTTN	Q05655	PRKCD	S277	G271C	271	Missense	distal	-6	no	9.333	9.411	EPSD	ICGC	7.604	Up-regulation
AGC_PKC_PKCd_PRKCD_ST	Q14247	CTTN	Q05655	PRKCD	S277	S282F	282	Missense	distal	5	no	9.333	9.122	EPSD	ICGC	7.604	Down-regulation
AGC_PKC_PKCd_PRKCD_ST	Q14247	CTTN	Q05655	PRKCD	S277	K272E	272	Missense	distal	-5	no	9.333	8.975	EPSD	ICGC;COSMIC	7.604	Down-regulation
AGC_PKC_PKCd_PRKCD_ST	Q14247	CTTN	Q05655	PRKCD	S277	E278D	278	Missense	proximal	1	no	9.333	9.305	EPSD	ICGC	7.604	Down-regulation
AGC_PKC_PKCd_PRKCD_ST	Q14247	CTTN	Q05655	PRKCD	S282	D288N	288	Missense	distal	6	no	8.343	8.335	EPSD	ICGC;COSMIC	7.604	Down-regulation
AGC_PKC_PKCd_PRKCD_ST	Q14247	CTTN	Q05655	PRKCD	S282	A283V	283	Missense	proximal	1	no	8.343	8.326	EPSD	ICGC;COSMIC	7.604	Down-regulation
AGC_PKC_PKCd_PRKCD_ST	Q14247	CTTN	Q05655	PRKCD	S282	D288H	288	Missense	distal	6	no	8.343	8.346	EPSD	ICGC;COSMIC	7.604	Up-regulation
AGC_PKC_PKCd_PRKCD_ST	Q14247	CTTN	Q05655	PRKCD	S282	V275F	275	Missense	distal	-7	no	8.343	8.344	EPSD	ICGC;COSMIC	7.604	Up-regulation
AGC_PKC_PKCd_PRKCD_ST	Q14247	CTTN	Q05655	PRKCD	S282	S282F	282	Missense	central	0	yes	8.343	0.000	EPSD	ICGC	7.604	Loss
AGC_PKC_PKCd_PRKCD_ST	Q14247	CTTN	Q05655	PRKCD	S282	E278D	278	Missense	distal	-4	no	8.343	8.338	EPSD	ICGC	7.604	Down-regulation
AGC_PKC_PKCd_PRKCD_ST	Q14247	CTTN	Q05655	PRKCD	S348	T347A	347	Missense	proximal	-1	no	8.086	8.070	EPSD	ICGC;COSMIC	7.604	Down-regulation
AGC_PKC_PKCd_PRKCD_ST	Q14247	CTTN	Q05655	PRKCD	S348	A352V	352	Missense	distal	4	no	8.086	7.931	EPSD	ICGC;COSMIC	7.604	Down-regulation
AGC_PKC_PKCd_PRKCD_ST	Q14247	CTTN	Q05655	PRKCD	S417	L415P	415	Missense	proximal	-2	no	6.433	8.103	EPSD	ICGC	7.604	Gain
AGC_PKC_PKCd_PRKCD_ST	P98082	DAB2	Q05655	PRKCD	S24	A19S	19	Missense	distal	-5	no	12.739	12.807	PhosphoSitePlus	ICGC	7.604	Up-regulation
AGC_PKC_PKCd_PRKCD_ST	P98082	DAB2	Q05655	PRKCD	S249	S249C	249	Missense	central	0	yes	8.261	0.000	EPSD	ICGC;COSMIC	7.604	Loss
AGC_PKC_PKCd_PRKCD_ST	P98082	DAB2	Q05655	PRKCD	S249	T245A	245	Missense	distal	-4	no	8.261	8.292	EPSD	ICGC;COSMIC	7.604	Up-regulation
AGC_PKC_PKCd_PRKCD_ST	P98082	DAB2	Q05655	PRKCD	S249	Q247K	247	Missense	proximal	-2	no	8.261	12.450	EPSD	ICGC	7.604	Up-regulation
AGC_PKC_PKCd_PRKCD_ST	P98082	DAB2	Q05655	PRKCD	S249	P254L	254	Missense	distal	5	no	8.261	8.039	EPSD	ICGC	7.604	Down-regulation
AGC_PKC_PKCd_PRKCD_ST	P98082	DAB2	Q05655	PRKCD	S313	S310L	310	Missense	distal	-3	no	9.632	9.021	EPSD	ICGC;COSMIC;GDSC;CCLE	7.604	Down-regulation
AGC_PKC_PKCd_PRKCD_ST	P98082	DAB2	Q05655	PRKCD	S436	P433H	433	Missense	distal	-3	no	10.180	10.168	EPSD	ICGC;COSMIC	7.604	Down-regulation
AGC_PKC_PKCd_PRKCD_ST	Q9Y2R2	PTPN22	Q05655	PRKCD	T318	N316K	316	Missense	proximal	-2	no	4.135	8.865	EPSD	ICGC;COSMIC	7.604	Gain
AGC_PKC_PKCd_PRKCD_ST	Q9Y2R2	PTPN22	Q05655	PRKCD	S550	Q557K	557	Missense	distal	7	no	7.568	7.688	EPSD	ICGC	7.604	Gain
AGC_PKC_PKCd_PRKCD_ST	Q9Y2R2	PTPN22	Q05655	PRKCD	S692	R690L	690	Missense	proximal	-2	no	9.496	3.363	EPSD	ICGC;COSMIC	7.604	Loss
AGC_PKC_PKCd_PRKCD_ST	Q9Y2R2	PTPN22	Q05655	PRKCD	S692	E699K	699	Missense	distal	7	no	9.496	9.633	EPSD	ICGC;COSMIC	7.604	Up-regulation
AGC_PKC_PKCd_PRKCD_ST	Q15139	PRKD1	Q05655	PRKCD	S153	V151G	151	Missense	proximal	-2	no	11.018	10.696	EPSD	ICGC	7.604	Down-regulation
AGC_PKC_PKCd_PRKCD_ST	Q15139	PRKD1	Q05655	PRKCD	S153	H147Y	147	Missense	distal	-6	no	11.018	11.184	EPSD	ICGC;COSMIC	7.604	Up-regulation
AGC_PKC_PKCd_PRKCD_ST	Q15139	PRKD1	Q05655	PRKCD	S153	H152R	152	Missense	proximal	-1	no	11.018	11.163	EPSD	ICGC;COSMIC	7.604	Up-regulation
AGC_PKC_PKCd_PRKCD_ST	Q15139	PRKD1	Q05655	PRKCD	S205	R203S	203	Missense	proximal	-2	no	14.171	9.323	EPSD	ICGC;COSMIC	7.604	Down-regulation
AGC_PKC_PKCd_PRKCD_ST	Q15139	PRKD1	Q05655	PRKCD	S205	G198S	198	Missense	distal	-7	no	14.171	14.182	EPSD	ICGC;COSMIC	7.604	Up-regulation
AGC_PKC_PKCd_PRKCD_ST	Q15139	PRKD1	Q05655	PRKCD	S205	V207F	207	Missense	proximal	2	no	14.171	14.422	EPSD	ICGC;COSMIC	7.604	Up-regulation
AGC_PKC_PKCd_PRKCD_ST	Q15139	PRKD1	Q05655	PRKCD	S205	G198C	198	Missense	distal	-7	no	14.171	14.168	EPSD	ICGC;COSMIC	7.604	Down-regulation
AGC_PKC_PKCd_PRKCD_ST	Q15139	PRKD1	Q05655	PRKCD	S412	R418K	418	Missense	distal	6	no	8.277	8.279	EPSD;PhosphoSitePlus	ICGC;COSMIC	7.604	Up-regulation
AGC_PKC_PKCd_PRKCD_ST	Q15139	PRKD1	Q05655	PRKCD	S420	R418K	418	Missense	proximal	-2	no	11.256	10.011	EPSD	ICGC;COSMIC	7.604	Down-regulation
AGC_PKC_PKCd_PRKCD_ST	Q15139	PRKD1	Q05655	PRKCD	S420	M424T	424	Missense	distal	4	no	11.256	11.432	EPSD	ICGC;COSMIC	7.604	Up-regulation
AGC_PKC_PKCd_PRKCD_ST	Q15139	PRKD1	Q05655	PRKCD	S421	R418K	418	Missense	distal	-3	no	10.023	8.987	EPSD	ICGC;COSMIC	7.604	Down-regulation
AGC_PKC_PKCd_PRKCD_ST	Q15139	PRKD1	Q05655	PRKCD	S421	M424T	424	Missense	distal	3	no	10.023	10.153	EPSD	ICGC;COSMIC	7.604	Up-regulation
AGC_PKC_PKCd_PRKCD_ST	Q15139	PRKD1	Q05655	PRKCD	S738	R740W	740	Missense	proximal	2	no	8.804	2.132	EPSD;PhosphoSitePlus	ICGC;COSMIC;GDSC;CCLE	7.604	Loss
AGC_PKC_PKCd_PRKCD_ST	Q15139	PRKD1	Q05655	PRKCD	S738	R740L	740	Missense	proximal	2	no	8.804	1.927	EPSD;PhosphoSitePlus	ICGC;COSMIC	7.604	Loss
AGC_PKC_PKCd_PRKCD_ST	Q15139	PRKD1	Q05655	PRKCD	S742	R740W	740	Missense	proximal	-2	no	9.075	2.821	PhosphoSitePlus;EPSD	ICGC;COSMIC;GDSC;CCLE	7.604	Loss
AGC_PKC_PKCd_PRKCD_ST	Q15139	PRKD1	Q05655	PRKCD	S742	R740L	740	Missense	proximal	-2	no	9.075	2.942	PhosphoSitePlus;EPSD	ICGC;COSMIC	7.604	Loss
AGC_PKC_PKCd_PRKCD_ST	Q15139	PRKD1	Q05655	PRKCD	S829	V830L	830	Missense	proximal	1	no	11.806	11.847	EPSD	ICGC;COSMIC	7.604	Up-regulation
AGC_PKC_PKCd_PRKCD_ST	P05230	FGF1	Q05655	PRKCD	S131	R137L	137	Missense	distal	6	no	12.592	12.529	PhosphoSitePlus	ICGC;COSMIC	7.604	Down-regulation
AGC_PKC_PKCd_PRKCD_ST	P28329	CHAT	Q05655	PRKCD	S594	L597F	597	Missense	distal	3	no	9.664	9.732	EPSD	ICGC;COSMIC	7.604	Up-regulation
AGC_PKC_PKCd_PRKCD_ST	P28329	CHAT	Q05655	PRKCD	S594	A590T	590	Missense	distal	-4	no	9.664	9.633	EPSD	ICGC;COSMIC	7.604	Down-regulation
AGC_PKC_PKCd_PRKCD_ST	P13498	CYBA	Q05655	PRKCD	S168	V174A	174	Missense	distal	6	no	10.563	10.580	EPSD	ICGC;COSMIC	7.604	Up-regulation
AGC_PKC_PKCd_PRKCD_ST	P13498	CYBA	Q05655	PRKCD	S168	K165R	165	Missense	distal	-3	no	10.563	11.598	EPSD	ICGC	7.604	Up-regulation
AGC_PKC_PKCd_PRKCD_ST	P13498	CYBA	Q05655	PRKCD	S168	A172S	172	Missense	distal	4	no	10.563	10.631	EPSD	ICGC;COSMIC	7.604	Up-regulation
AGC_PKC_PKCd_PRKCD_ST	P04637	TP53	Q05655	PRKCD	S9	E11K	11	Missense	proximal	2	no	2.751	8.506	EPSD	ICGC;COSMIC	7.604	Gain
AGC_PKC_PKCd_PRKCD_ST	P04637	TP53	Q05655	PRKCD	S99	Q100K	100	Missense	proximal	1	no	8.382	8.530	EPSD	ICGC;COSMIC	7.604	Up-regulation
AGC_PKC_PKCd_PRKCD_ST	P04637	TP53	Q05655	PRKCD	S99	P92T	92	Missense	distal	-7	no	8.382	8.378	EPSD	ICGC;COSMIC	7.604	Down-regulation
AGC_PKC_PKCd_PRKCD_ST	P04637	TP53	Q05655	PRKCD	S99	P92H	92	Missense	distal	-7	no	8.382	8.377	EPSD	ICGC;COSMIC	7.604	Down-regulation
AGC_PKC_PKCd_PRKCD_ST	P04637	TP53	Q05655	PRKCD	S99	G105A	105	Missense	distal	6	no	8.382	8.391	EPSD	ICGC;COSMIC	7.604	Up-regulation
AGC_PKC_PKCd_PRKCD_ST	P04637	TP53	Q05655	PRKCD	S127	T125R	125	Missense	proximal	-2	no	1.906	7.869	EPSD	ICGC;COSMIC	7.604	Gain
AGC_PKC_PKCd_PRKCD_ST	P04637	TP53	Q05655	PRKCD	S183	C182W	182	Missense	proximal	-1	no	7.852	7.791	EPSD	ICGC;COSMIC	7.604	Down-regulation
AGC_PKC_PKCd_PRKCD_ST	P04637	TP53	Q05655	PRKCD	S183	H178D	178	Missense	distal	-5	no	7.852	7.807	EPSD	ICGC;COSMIC;CCLE	7.604	Down-regulation
AGC_PKC_PKCd_PRKCD_ST	P04637	TP53	Q05655	PRKCD	S183	D184H	184	Missense	proximal	1	no	7.852	7.889	EPSD	ICGC;COSMIC	7.604	Up-regulation
AGC_PKC_PKCd_PRKCD_ST	P04637	TP53	Q05655	PRKCD	S183	A189T	189	Missense	distal	6	no	7.852	7.863	EPSD	ICGC;COSMIC	7.604	Up-regulation
AGC_PKC_PKCd_PRKCD_ST	P04637	TP53	Q05655	PRKCD	S183	P190T	190	Missense	distal	7	no	7.852	7.873	EPSD	ICGC;COSMIC	7.604	Up-regulation
AGC_PKC_PKCd_PRKCD_ST	P04637	TP53	Q05655	PRKCD	S183	P190S	190	Missense	distal	7	no	7.852	7.881	EPSD	ICGC;COSMIC	7.604	Up-regulation
AGC_PKC_PKCd_PRKCD_ST	P04637	TP53	Q05655	PRKCD	S183	A189D	189	Missense	distal	6	no	7.852	7.850	EPSD	ICGC;COSMIC	7.604	Down-regulation
AGC_PKC_PKCd_PRKCD_ST	P04637	TP53	Q05655	PRKCD	S183	E180D	180	Missense	distal	-3	no	7.852	8.233	EPSD	ICGC;COSMIC	7.604	Up-regulation
AGC_PKC_PKCd_PRKCD_ST	P04637	TP53	Q05655	PRKCD	S183	C176G	176	Missense	distal	-7	no	7.852	7.856	EPSD	ICGC;COSMIC	7.604	Up-regulation
AGC_PKC_PKCd_PRKCD_ST	P04637	TP53	Q05655	PRKCD	T211	H214D	214	Missense	distal	3	no	12.679	12.463	EPSD	ICGC;COSMIC	7.604	Down-regulation
AGC_PKC_PKCd_PRKCD_ST	P04637	TP53	Q05655	PRKCD	T211	H214Y	214	Missense	distal	3	no	12.679	12.232	EPSD	ICGC;COSMIC	7.604	Down-regulation
AGC_PKC_PKCd_PRKCD_ST	P04637	TP53	Q05655	PRKCD	T211	T211P	211	Missense	central	0	yes	12.679	0.000	EPSD	ICGC;COSMIC	7.604	Loss
AGC_PKC_PKCd_PRKCD_ST	P04637	TP53	Q05655	PRKCD	T211	F212V	212	Missense	proximal	1	no	12.679	12.632	EPSD	ICGC;COSMIC	7.604	Down-regulation
AGC_PKC_PKCd_PRKCD_ST	P04637	TP53	Q05655	PRKCD	T211	D208V	208	Missense	distal	-3	no	12.679	12.918	EPSD	ICGC;COSMIC	7.604	Up-regulation
AGC_PKC_PKCd_PRKCD_ST	P04637	TP53	Q05655	PRKCD	T211	V217G	217	Missense	distal	6	no	12.679	12.687	EPSD	ICGC;COSMIC;CCLE	7.604	Up-regulation
AGC_PKC_PKCd_PRKCD_ST	P04637	TP53	Q05655	PRKCD	T211	S215T	215	Missense	distal	4	no	12.679	12.643	EPSD	ICGC;COSMIC	7.604	Down-regulation
AGC_PKC_PKCd_PRKCD_ST	P04637	TP53	Q05655	PRKCD	S215	P219T	219	Missense	distal	4	no	7.714	7.641	EPSD	ICGC;COSMIC	7.604	Down-regulation
AGC_PKC_PKCd_PRKCD_ST	P04637	TP53	Q05655	PRKCD	S215	H214D	214	Missense	proximal	-1	no	7.714	7.698	EPSD	ICGC;COSMIC	7.604	Down-regulation
AGC_PKC_PKCd_PRKCD_ST	P04637	TP53	Q05655	PRKCD	S215	Y220N	220	Missense	distal	5	no	7.714	7.835	EPSD	ICGC;COSMIC	7.604	Up-regulation
AGC_PKC_PKCd_PRKCD_ST	P04637	TP53	Q05655	PRKCD	S215	E221V	221	Missense	distal	6	no	7.714	7.699	EPSD	ICGC;COSMIC	7.604	Down-regulation
AGC_PKC_PKCd_PRKCD_ST	P04637	TP53	Q05655	PRKCD	S215	E221K	221	Missense	distal	6	no	7.714	7.770	EPSD	ICGC;COSMIC	7.604	Up-regulation
AGC_PKC_PKCd_PRKCD_ST	P04637	TP53	Q05655	PRKCD	S215	H214Y	214	Missense	proximal	-1	no	7.714	7.639	EPSD	ICGC;COSMIC	7.604	Down-regulation
AGC_PKC_PKCd_PRKCD_ST	P04637	TP53	Q05655	PRKCD	S215	T211P	211	Missense	distal	-4	no	7.714	7.684	EPSD	ICGC;COSMIC	7.604	Down-regulation
AGC_PKC_PKCd_PRKCD_ST	P04637	TP53	Q05655	PRKCD	S215	F212V	212	Missense	distal	-3	no	7.714	7.437	EPSD	ICGC;COSMIC	7.604	Loss
AGC_PKC_PKCd_PRKCD_ST	P04637	TP53	Q05655	PRKCD	S215	D208V	208	Missense	distal	-7	no	7.714	7.710	EPSD	ICGC;COSMIC	7.604	Down-regulation
AGC_PKC_PKCd_PRKCD_ST	P04637	TP53	Q05655	PRKCD	S215	V217G	217	Missense	proximal	2	no	7.714	7.753	EPSD	ICGC;COSMIC;CCLE	7.604	Up-regulation
AGC_PKC_PKCd_PRKCD_ST	P04637	TP53	Q05655	PRKCD	S269	A276V	276	Missense	distal	7	no	8.933	8.895	EPSD	ICGC;COSMIC	7.604	Down-regulation
AGC_PKC_PKCd_PRKCD_ST	P04637	TP53	Q05655	PRKCD	S269	V274A	274	Missense	distal	5	no	8.933	9.054	EPSD	ICGC;COSMIC	7.604	Up-regulation
AGC_PKC_PKCd_PRKCD_ST	P04637	TP53	Q05655	PRKCD	S269	V272E	272	Missense	distal	3	no	8.933	8.913	EPSD	ICGC;COSMIC;CCLE	7.604	Down-regulation
AGC_PKC_PKCd_PRKCD_ST	P04637	TP53	Q05655	PRKCD	S269	L265T	265	Missense	distal	-4	no	8.933	8.824	EPSD	ICGC	7.604	Down-regulation
AGC_PKC_PKCd_PRKCD_ST	P04637	TP53	Q05655	PRKCD	S269	N268I	268	Missense	proximal	-1	no	8.933	8.895	EPSD	ICGC;COSMIC;GDSC;CCLE	7.604	Down-regulation
AGC_PKC_PKCd_PRKCD_ST	P04637	TP53	Q05655	PRKCD	S269	E271D	271	Missense	proximal	2	no	8.933	9.400	EPSD	ICGC;COSMIC	7.604	Up-regulation
AGC_PKC_PKCd_PRKCD_ST	P04637	TP53	Q05655	PRKCD	S371	G374C	374	Missense	distal	3	no	9.551	9.413	EPSD	ICGC;COSMIC	7.604	Down-regulation
AGC_PKC_PKCd_PRKCD_ST	P04637	TP53	Q05655	PRKCD	S376	T377P	377	Missense	proximal	1	no	8.153	8.190	EPSD	ICGC;COSMIC	7.604	Up-regulation
AGC_PKC_PKCd_PRKCD_ST	P04637	TP53	Q05655	PRKCD	S376	G374C	374	Missense	proximal	-2	no	8.153	7.922	EPSD	ICGC;COSMIC	7.604	Down-regulation
AGC_PKC_PKCd_PRKCD_ST	P04637	TP53	Q05655	PRKCD	S376	R379S	379	Missense	distal	3	no	8.153	7.296	EPSD	ICGC	7.604	Loss
AGC_PKC_PKCd_PRKCD_ST	P04637	TP53	Q05655	PRKCD	S376	R379C	379	Missense	distal	3	no	8.153	6.878	EPSD	ICGC;COSMIC	7.604	Loss
AGC_PKC_PKCd_PRKCD_ST	P04637	TP53	Q05655	PRKCD	T377	T377P	377	Missense	central	0	yes	8.421	0.000	EPSD	ICGC;COSMIC	7.604	Loss
AGC_PKC_PKCd_PRKCD_ST	P04637	TP53	Q05655	PRKCD	T377	G374C	374	Missense	distal	-3	no	8.421	8.311	EPSD	ICGC;COSMIC	7.604	Down-regulation
AGC_PKC_PKCd_PRKCD_ST	P04637	TP53	Q05655	PRKCD	T377	R379S	379	Missense	proximal	2	no	8.421	2.358	EPSD	ICGC	7.604	Loss
AGC_PKC_PKCd_PRKCD_ST	P04637	TP53	Q05655	PRKCD	T377	R379C	379	Missense	proximal	2	no	8.421	1.543	EPSD	ICGC;COSMIC	7.604	Loss
AGC_PKC_PKCd_PRKCD_ST	P06401	PGR	Q05655	PRKCD	S190	L189M	189	Missense	proximal	-1	no	9.830	9.826	EPSD	ICGC	7.604	Down-regulation
AGC_PKC_PKCd_PRKCD_ST	P06401	PGR	Q05655	PRKCD	S190	R193Q	193	Missense	distal	3	no	9.830	8.752	EPSD	ICGC;COSMIC	7.604	Down-regulation
AGC_PKC_PKCd_PRKCD_ST	P06401	PGR	Q05655	PRKCD	S190	K183N	183	Missense	distal	-7	no	9.830	9.805	EPSD	ICGC	7.604	Down-regulation
AGC_PKC_PKCd_PRKCD_ST	P06401	PGR	Q05655	PRKCD	S276	E271D	271	Missense	distal	-5	no	10.275	10.278	EPSD	ICGC;COSMIC	7.604	Up-regulation
AGC_PKC_PKCd_PRKCD_ST	P06401	PGR	Q05655	PRKCD	S276	F275L	275	Missense	proximal	-1	no	10.275	10.266	EPSD	ICGC;COSMIC	7.604	Down-regulation
AGC_PKC_PKCd_PRKCD_ST	P06401	PGR	Q05655	PRKCD	S397	S400F	400	Missense	distal	3	no	8.825	8.606	EPSD	ICGC;COSMIC	7.604	Down-regulation
AGC_PKC_PKCd_PRKCD_ST	P06401	PGR	Q05655	PRKCD	S400	S400F	400	Missense	central	0	yes	10.978	0.000	PhosphoSitePlus	ICGC;COSMIC	7.604	Loss
AGC_PKC_PKCd_PRKCD_ST	P06401	PGR	Q05655	PRKCD	S549	P555Q	555	Missense	distal	6	no	9.693	9.685	EPSD	ICGC;COSMIC;GDSC;CCLE	7.604	Down-regulation
AGC_PKC_PKCd_PRKCD_ST	Q8TCU6	PREX1	Q05655	PRKCD	S43	A38V	38	Missense	distal	-5	no	15.026	14.940	EPSD	ICGC;COSMIC	7.604	Down-regulation
AGC_PKC_PKCd_PRKCD_ST	Q8TCU6	PREX1	Q05655	PRKCD	S43	P36Q	36	Missense	distal	-7	no	15.026	15.022	EPSD	ICGC;COSMIC	7.604	Down-regulation
AGC_PKC_PKCd_PRKCD_ST	Q8TCU6	PREX1	Q05655	PRKCD	T308	S310R	310	Missense	proximal	2	no	8.800	14.863	EPSD	ICGC;COSMIC	7.604	Up-regulation
AGC_PKC_PKCd_PRKCD_ST	Q8TCU6	PREX1	Q05655	PRKCD	T308	T308N	308	Missense	central	0	yes	8.800	0.000	EPSD	ICGC	7.604	Loss
AGC_PKC_PKCd_PRKCD_ST	Q8TCU6	PREX1	Q05655	PRKCD	T308	K302Q	302	Missense	distal	-6	no	8.800	9.152	EPSD	ICGC;COSMIC	7.604	Up-regulation
AGC_PKC_PKCd_PRKCD_ST	Q8TCU6	PREX1	Q05655	PRKCD	S310	S310R	310	Missense	central	0	yes	7.760	0.000	EPSD	ICGC;COSMIC	7.604	Loss
AGC_PKC_PKCd_PRKCD_ST	Q8TCU6	PREX1	Q05655	PRKCD	S310	T308N	308	Missense	proximal	-2	no	7.760	7.747	EPSD	ICGC	7.604	Down-regulation
AGC_PKC_PKCd_PRKCD_ST	Q8TCU6	PREX1	Q05655	PRKCD	S313	S310R	310	Missense	distal	-3	no	13.449	18.024	PhosphoSitePlus	ICGC;COSMIC	7.604	Up-regulation
AGC_PKC_PKCd_PRKCD_ST	Q8TCU6	PREX1	Q05655	PRKCD	S313	T308N	308	Missense	distal	-5	no	13.449	13.345	PhosphoSitePlus	ICGC	7.604	Down-regulation
AGC_PKC_PKCd_PRKCD_ST	Q8TCU6	PREX1	Q05655	PRKCD	T314	S310R	310	Missense	distal	-4	no	15.960	15.728	EPSD	ICGC;COSMIC	7.604	Down-regulation
AGC_PKC_PKCd_PRKCD_ST	Q8TCU6	PREX1	Q05655	PRKCD	T314	T308N	308	Missense	distal	-6	no	15.960	16.119	EPSD	ICGC	7.604	Up-regulation
AGC_PKC_PKCd_PRKCD_ST	Q8TCU6	PREX1	Q05655	PRKCD	S436	P439H	439	Missense	distal	3	no	12.642	12.617	EPSD	ICGC;COSMIC	7.604	Down-regulation
AGC_PKC_PKCd_PRKCD_ST	Q8TCU6	PREX1	Q05655	PRKCD	S436	R432W	432	Missense	distal	-4	no	12.642	13.174	EPSD	ICGC;COSMIC	7.604	Up-regulation
AGC_PKC_PKCd_PRKCD_ST	Q8TCU6	PREX1	Q05655	PRKCD	S436	C441S	441	Missense	distal	5	no	12.642	12.979	EPSD	ICGC;COSMIC	7.604	Up-regulation
AGC_PKC_PKCd_PRKCD_ST	Q8TCU6	PREX1	Q05655	PRKCD	S1359	R1365H	1365	Missense	distal	6	no	8.272	8.222	EPSD	ICGC;COSMIC;CCLE	7.604	Down-regulation
AGC_PKC_PKCd_PRKCD_ST	Q8TCU6	PREX1	Q05655	PRKCD	S1359	R1365C	1365	Missense	distal	6	no	8.272	8.196	EPSD	ICGC;CCLE	7.604	Down-regulation
AGC_PKC_PKCd_PRKCD_ST	Q8TCU6	PREX1	Q05655	PRKCD	S1359	A1363T	1363	Missense	distal	4	no	8.272	8.303	EPSD	ICGC;COSMIC	7.604	Up-regulation
AGC_PKC_PKCd_PRKCD_ST	Q8TCU6	PREX1	Q05655	PRKCD	S1359	N1352S	1352	Missense	distal	-7	no	8.272	8.283	EPSD	ICGC;COSMIC	7.604	Up-regulation
AGC_PKC_PKCd_PRKCD_ST	Q8TCU6	PREX1	Q05655	PRKCD	S1359	N1352K	1352	Missense	distal	-7	no	8.272	8.296	EPSD	ICGC;COSMIC	7.604	Up-regulation
AGC_PKC_PKCd_PRKCD_ST	P78536	ADAM17	Q05655	PRKCD	S608	P613T	613	Missense	distal	5	no	13.823	13.694	EPSD	ICGC	7.604	Down-regulation
AGC_PKC_PKCd_PRKCD_ST	P21730	C5AR1	Q05655	PRKCD	S314	R312W	312	Missense	proximal	-2	no	8.341	2.087	EPSD	ICGC;COSMIC	7.604	Loss
AGC_PKC_PKCd_PRKCD_ST	P21730	C5AR1	Q05655	PRKCD	S332	R337C	337	Missense	distal	5	no	9.823	9.258	EPSD	ICGC;COSMIC;CCLE	7.604	Down-regulation
AGC_PKC_PKCd_PRKCD_ST	P21730	C5AR1	Q05655	PRKCD	S332	S327F	327	Missense	distal	-5	no	9.823	9.714	EPSD	ICGC	7.604	Down-regulation
AGC_PKC_PKCd_PRKCD_ST	P35568	IRS1	Q05655	PRKCD	S24	K23N	23	Missense	proximal	-1	no	11.075	10.894	EPSD	ICGC;COSMIC	7.604	Down-regulation
AGC_PKC_PKCd_PRKCD_ST	P35568	IRS1	Q05655	PRKCD	S268	R265H	265	Missense	distal	-3	no	8.493	4.238	EPSD	ICGC	7.604	Loss
AGC_PKC_PKCd_PRKCD_ST	P35568	IRS1	Q05655	PRKCD	S268	F264L	264	Missense	distal	-4	no	8.493	8.522	EPSD	ICGC	7.604	Up-regulation
AGC_PKC_PKCd_PRKCD_ST	P35568	IRS1	Q05655	PRKCD	S268	S272P	272	Missense	distal	4	no	8.493	8.531	EPSD	ICGC	7.604	Up-regulation
AGC_PKC_PKCd_PRKCD_ST	P35568	IRS1	Q05655	PRKCD	S268	S268I	268	Missense	central	0	yes	8.493	0.000	EPSD	ICGC;COSMIC	7.604	Loss
AGC_PKC_PKCd_PRKCD_ST	P35568	IRS1	Q05655	PRKCD	S270	R265H	265	Missense	distal	-5	no	9.706	9.370	EPSD	ICGC	7.604	Down-regulation
AGC_PKC_PKCd_PRKCD_ST	P35568	IRS1	Q05655	PRKCD	S270	F264L	264	Missense	distal	-6	no	9.706	9.746	EPSD	ICGC	7.604	Up-regulation
AGC_PKC_PKCd_PRKCD_ST	P35568	IRS1	Q05655	PRKCD	S270	S272P	272	Missense	proximal	2	no	9.706	9.951	EPSD	ICGC	7.604	Up-regulation
AGC_PKC_PKCd_PRKCD_ST	P35568	IRS1	Q05655	PRKCD	S270	S268I	268	Missense	proximal	-2	no	9.706	7.830	EPSD	ICGC;COSMIC	7.604	Down-regulation
AGC_PKC_PKCd_PRKCD_ST	P35568	IRS1	Q05655	PRKCD	S272	S268I	268	Missense	distal	-4	no	7.493	7.704	EPSD	ICGC;COSMIC	7.604	Gain
AGC_PKC_PKCd_PRKCD_ST	P35568	IRS1	Q05655	PRKCD	S307	T300P	300	Missense	distal	-7	no	8.043	8.047	EPSD;PhosphoSitePlus	ICGC;COSMIC;GDSC	7.604	Up-regulation
AGC_PKC_PKCd_PRKCD_ST	P35568	IRS1	Q05655	PRKCD	S323	G319R	319	Missense	distal	-4	no	13.662	13.278	EPSD;PhosphoSitePlus	ICGC;COSMIC	7.604	Down-regulation
AGC_PKC_PKCd_PRKCD_ST	P35568	IRS1	Q05655	PRKCD	S341	S345N	345	Missense	distal	4	no	7.893	7.710	EPSD	ICGC	7.604	Down-regulation
AGC_PKC_PKCd_PRKCD_ST	P35568	IRS1	Q05655	PRKCD	T351	H355Q	355	Missense	distal	4	no	7.871	7.825	EPSD	ICGC	7.604	Down-regulation
AGC_PKC_PKCd_PRKCD_ST	P35568	IRS1	Q05655	PRKCD	T351	S345N	345	Missense	distal	-6	no	7.871	8.070	EPSD	ICGC	7.604	Up-regulation
AGC_PKC_PKCd_PRKCD_ST	P35568	IRS1	Q05655	PRKCD	S362	H355Q	355	Missense	distal	-7	no	14.525	14.526	EPSD	ICGC	7.604	Up-regulation
AGC_PKC_PKCd_PRKCD_ST	P35568	IRS1	Q05655	PRKCD	S362	L369H	369	Missense	distal	7	no	14.525	14.561	EPSD	ICGC;COSMIC	7.604	Up-regulation
AGC_PKC_PKCd_PRKCD_ST	P35568	IRS1	Q05655	PRKCD	S383	P389T	389	Missense	distal	6	no	7.873	7.872	EPSD	ICGC	7.604	Down-regulation
AGC_PKC_PKCd_PRKCD_ST	P35568	IRS1	Q05655	PRKCD	S412	S412P	412	Missense	central	0	yes	8.948	0.000	EPSD	ICGC	7.604	Loss
AGC_PKC_PKCd_PRKCD_ST	P35568	IRS1	Q05655	PRKCD	S412	A414D	414	Missense	proximal	2	no	8.948	7.706	EPSD	ICGC	7.604	Down-regulation
AGC_PKC_PKCd_PRKCD_ST	P35568	IRS1	Q05655	PRKCD	S412	R411L	411	Missense	proximal	-1	no	8.948	8.757	EPSD	ICGC;COSMIC	7.604	Down-regulation
AGC_PKC_PKCd_PRKCD_ST	P35568	IRS1	Q05655	PRKCD	S412	R410W	410	Missense	proximal	-2	no	8.948	2.694	EPSD	ICGC	7.604	Loss
AGC_PKC_PKCd_PRKCD_ST	P35568	IRS1	Q05655	PRKCD	S413	S412P	412	Missense	proximal	-1	no	12.056	12.015	EPSD	ICGC	7.604	Down-regulation
AGC_PKC_PKCd_PRKCD_ST	P35568	IRS1	Q05655	PRKCD	S413	A414D	414	Missense	proximal	1	no	12.056	12.058	EPSD	ICGC	7.604	Up-regulation
AGC_PKC_PKCd_PRKCD_ST	P35568	IRS1	Q05655	PRKCD	S413	R411L	411	Missense	proximal	-2	no	12.056	5.923	EPSD	ICGC;COSMIC	7.604	Loss
AGC_PKC_PKCd_PRKCD_ST	P35568	IRS1	Q05655	PRKCD	S413	R410W	410	Missense	distal	-3	no	12.056	6.760	EPSD	ICGC	7.604	Loss
AGC_PKC_PKCd_PRKCD_ST	P35568	IRS1	Q05655	PRKCD	S441	D437Y	437	Missense	distal	-4	no	14.704	14.796	EPSD;PhosphoSitePlus	ICGC;COSMIC	7.604	Up-regulation
AGC_PKC_PKCd_PRKCD_ST	P35568	IRS1	Q05655	PRKCD	T525	S531Y	531	Missense	distal	6	no	10.973	10.932	EPSD	ICGC	7.604	Down-regulation
AGC_PKC_PKCd_PRKCD_ST	P35568	IRS1	Q05655	PRKCD	S603	R600H	600	Missense	distal	-3	no	8.411	4.156	EPSD	ICGC;COSMIC	7.604	Loss
AGC_PKC_PKCd_PRKCD_ST	P35568	IRS1	Q05655	PRKCD	S624	K627N	627	Missense	distal	3	no	8.167	7.033	EPSD	ICGC;COSMIC	7.604	Loss
AGC_PKC_PKCd_PRKCD_ST	P35568	IRS1	Q05655	PRKCD	S629	P634S	634	Missense	distal	5	no	9.763	9.731	EPSD	ICGC;COSMIC	7.604	Down-regulation
AGC_PKC_PKCd_PRKCD_ST	P35568	IRS1	Q05655	PRKCD	S629	Y632C	632	Missense	distal	3	no	9.763	9.823	EPSD	ICGC;COSMIC	7.604	Up-regulation
AGC_PKC_PKCd_PRKCD_ST	P35568	IRS1	Q05655	PRKCD	S629	K627N	627	Missense	proximal	-2	no	9.763	5.034	EPSD	ICGC;COSMIC	7.604	Loss
AGC_PKC_PKCd_PRKCD_ST	P35568	IRS1	Q05655	PRKCD	S636	P634S	634	Missense	proximal	-2	no	10.727	10.342	EPSD	ICGC;COSMIC	7.604	Down-regulation
AGC_PKC_PKCd_PRKCD_ST	P35568	IRS1	Q05655	PRKCD	S636	Y632C	632	Missense	distal	-4	no	10.727	10.709	EPSD	ICGC;COSMIC	7.604	Down-regulation
AGC_PKC_PKCd_PRKCD_ST	P35568	IRS1	Q05655	PRKCD	S792	T793A	793	Missense	proximal	1	no	8.515	8.453	EPSD	ICGC;COSMIC	7.604	Down-regulation
AGC_PKC_PKCd_PRKCD_ST	P35568	IRS1	Q05655	PRKCD	S792	T793S	793	Missense	proximal	1	no	8.515	8.533	EPSD	ICGC;COSMIC	7.604	Up-regulation
AGC_PKC_PKCd_PRKCD_ST	P35568	IRS1	Q05655	PRKCD	S792	R790H	790	Missense	proximal	-2	no	8.515	3.539	EPSD	ICGC	7.604	Loss
AGC_PKC_PKCd_PRKCD_ST	P35568	IRS1	Q05655	PRKCD	S795	T793A	793	Missense	proximal	-2	no	7.681	8.833	EPSD	ICGC;COSMIC	7.604	Up-regulation
AGC_PKC_PKCd_PRKCD_ST	P35568	IRS1	Q05655	PRKCD	S795	Y800C	800	Missense	distal	5	no	7.681	7.683	EPSD	ICGC;COSMIC	7.604	Up-regulation
AGC_PKC_PKCd_PRKCD_ST	P35568	IRS1	Q05655	PRKCD	S795	T793S	793	Missense	proximal	-2	no	7.681	8.795	EPSD	ICGC;COSMIC	7.604	Up-regulation
AGC_PKC_PKCd_PRKCD_ST	P35568	IRS1	Q05655	PRKCD	S795	R790H	790	Missense	distal	-5	no	7.681	7.345	EPSD	ICGC	7.604	Loss
AGC_PKC_PKCd_PRKCD_ST	P35568	IRS1	Q05655	PRKCD	S862	K867T	867	Missense	distal	5	no	8.316	7.929	EPSD	ICGC	7.604	Down-regulation
AGC_PKC_PKCd_PRKCD_ST	P35568	IRS1	Q05655	PRKCD	S862	P866T	866	Missense	distal	4	no	8.316	8.242	EPSD	ICGC	7.604	Down-regulation
AGC_PKC_PKCd_PRKCD_ST	P35568	IRS1	Q05655	PRKCD	S869	K867T	867	Missense	proximal	-2	no	8.590	3.873	EPSD	ICGC	7.604	Loss
AGC_PKC_PKCd_PRKCD_ST	P35568	IRS1	Q05655	PRKCD	S869	R873P	873	Missense	distal	4	no	8.590	8.158	EPSD	ICGC	7.604	Down-regulation
AGC_PKC_PKCd_PRKCD_ST	P35568	IRS1	Q05655	PRKCD	S869	P866T	866	Missense	distal	-3	no	8.590	7.740	EPSD	ICGC	7.604	Down-regulation
AGC_PKC_PKCd_PRKCD_ST	P35568	IRS1	Q05655	PRKCD	S869	A874G	874	Missense	distal	5	no	8.590	8.511	EPSD	ICGC;COSMIC	7.604	Down-regulation
AGC_PKC_PKCd_PRKCD_ST	P35568	IRS1	Q05655	PRKCD	T870	K867T	867	Missense	distal	-3	no	7.797	3.739	EPSD	ICGC	7.604	Loss
AGC_PKC_PKCd_PRKCD_ST	P35568	IRS1	Q05655	PRKCD	T870	R873P	873	Missense	distal	3	no	7.797	6.934	EPSD	ICGC	7.604	Loss
AGC_PKC_PKCd_PRKCD_ST	P35568	IRS1	Q05655	PRKCD	T870	P866T	866	Missense	distal	-4	no	7.797	7.827	EPSD	ICGC	7.604	Up-regulation
AGC_PKC_PKCd_PRKCD_ST	P35568	IRS1	Q05655	PRKCD	T870	A874G	874	Missense	distal	4	no	7.797	7.666	EPSD	ICGC;COSMIC	7.604	Down-regulation
AGC_PKC_PKCd_PRKCD_ST	P35568	IRS1	Q05655	PRKCD	S1000	D1003N	1003	Missense	distal	3	no	8.052	8.027	EPSD	ICGC;COSMIC	7.604	Down-regulation
AGC_PKC_PKCd_PRKCD_ST	P35568	IRS1	Q05655	PRKCD	S1100	S1106L	1106	Missense	distal	6	no	12.851	12.821	EPSD	ICGC;COSMIC	7.604	Down-regulation
AGC_PKC_PKCd_PRKCD_ST	P35568	IRS1	Q05655	PRKCD	S1101	S1106L	1106	Missense	distal	5	no	9.221	9.031	EPSD	ICGC;COSMIC	7.604	Down-regulation
AGC_PKC_PKCd_PRKCD_ST	P35568	IRS1	Q05655	PRKCD	S1142	D1137N	1137	Missense	distal	-5	no	14.459	14.435	EPSD	ICGC	7.604	Down-regulation
AGC_PKC_PKCd_PRKCD_ST	P35568	IRS1	Q05655	PRKCD	S1143	D1137N	1137	Missense	distal	-6	no	8.725	8.772	EPSD	ICGC	7.604	Up-regulation
AGC_PKC_PKCd_PRKCD_ST	P35568	IRS1	Q05655	PRKCD	S1213	L1211R	1211	Missense	proximal	-2	no	2.088	8.221	EPSD	ICGC;COSMIC	7.604	Gain
AGC_PKC_PKCd_PRKCD_ST	P35568	IRS1	Q05655	PRKCD	S1218	L1211R	1211	Missense	distal	-7	no	11.542	11.565	EPSD	ICGC;COSMIC	7.604	Up-regulation
AGC_PKC_PKCd_PRKCD_ST	P35568	IRS1	Q05655	PRKCD	S1218	R1220H	1220	Missense	proximal	2	no	11.542	5.981	EPSD	ICGC;COSMIC	7.604	Loss
AGC_PKC_PKCd_PRKCD_ST	P35568	IRS1	Q05655	PRKCD	S1218	T1219P	1219	Missense	proximal	1	no	11.542	11.579	EPSD	ICGC;COSMIC;GDSC	7.604	Up-regulation
AGC_PKC_PKCd_PRKCD_ST	P35568	IRS1	Q05655	PRKCD	T1219	R1220H	1220	Missense	proximal	1	no	8.904	8.770	EPSD	ICGC;COSMIC	7.604	Down-regulation
AGC_PKC_PKCd_PRKCD_ST	P35568	IRS1	Q05655	PRKCD	T1219	T1219P	1219	Missense	central	0	yes	8.904	0.000	EPSD	ICGC;COSMIC;GDSC	7.604	Loss
AGC_PKC_PKCd_PRKCD_ST	P35568	IRS1	Q05655	PRKCD	S1222	R1220H	1220	Missense	proximal	-2	no	8.311	3.335	EPSD	ICGC;COSMIC	7.604	Loss
AGC_PKC_PKCd_PRKCD_ST	P35568	IRS1	Q05655	PRKCD	S1222	T1219P	1219	Missense	distal	-3	no	8.311	9.160	EPSD	ICGC;COSMIC;GDSC	7.604	Up-regulation
AGC_PKC_PKCd_PRKCD_ST	P35568	IRS1	Q05655	PRKCD	S1223	R1220H	1220	Missense	distal	-3	no	13.549	9.294	EPSD	ICGC;COSMIC	7.604	Down-regulation
AGC_PKC_PKCd_PRKCD_ST	P35568	IRS1	Q05655	PRKCD	S1223	T1219P	1219	Missense	distal	-4	no	13.549	13.518	EPSD	ICGC;COSMIC;GDSC	7.604	Down-regulation
AGC_PKC_PKCd_PRKCD_ST	Q96A00	PPP1R14A	Q05655	PRKCD	T38	Q31K	31	Missense	distal	-7	no	11.869	11.888	PhosphoSitePlus	ICGC	7.604	Up-regulation
AGC_PKC_PKCd_PRKCD_ST	Q96A00	PPP1R14A	Q05655	PRKCD	T38	H34Y	34	Missense	distal	-4	no	11.869	12.031	PhosphoSitePlus	ICGC;COSMIC	7.604	Up-regulation
AGC_PKC_PKCd_PRKCD_ST	Q96A00	PPP1R14A	Q05655	PRKCD	T38	H34Q	34	Missense	distal	-4	no	11.869	11.892	PhosphoSitePlus	ICGC	7.604	Up-regulation
AGC_PKC_PKCd_PRKCD_ST	Q96A00	PPP1R14A	Q05655	PRKCD	T38	A35T	35	Missense	distal	-3	no	11.869	11.116	PhosphoSitePlus	ICGC;COSMIC	7.604	Down-regulation
AGC_PKC_PKCd_PRKCD_ST	P11413	G6PD	Q05655	PRKCD	T76	A71V	71	Missense	distal	-5	no	8.054	7.968	EPSD	ICGC;COSMIC	7.604	Down-regulation
AGC_PKC_PKCd_PRKCD_ST	P11413	G6PD	Q05655	PRKCD	T76	R74S	74	Missense	proximal	-2	no	8.054	3.206	EPSD	ICGC;COSMIC	7.604	Loss
AGC_PKC_PKCd_PRKCD_ST	P11413	G6PD	Q05655	PRKCD	S84	F87L	87	Missense	distal	3	no	14.867	14.799	EPSD	ICGC;COSMIC	7.604	Down-regulation
AGC_PKC_PKCd_PRKCD_ST	P11413	G6PD	Q05655	PRKCD	S106	R104C	104	Missense	proximal	-2	no	8.039	2.045	EPSD	ICGC;COSMIC	7.604	Loss
AGC_PKC_PKCd_PRKCD_ST	P11413	G6PD	Q05655	PRKCD	S106	R104S	104	Missense	proximal	-2	no	8.039	3.191	EPSD	ICGC;COSMIC	7.604	Loss
AGC_PKC_PKCd_PRKCD_ST	P11413	G6PD	Q05655	PRKCD	S106	D100Y	100	Missense	distal	-6	no	8.039	8.153	EPSD	ICGC;COSMIC	7.604	Up-regulation
AGC_PKC_PKCd_PRKCD_ST	P11413	G6PD	Q05655	PRKCD	S106	S106F	106	Missense	central	0	yes	8.039	0.000	EPSD	ICGC;COSMIC	7.604	Loss
AGC_PKC_PKCd_PRKCD_ST	P11413	G6PD	Q05655	PRKCD	S123	R120S	120	Missense	distal	-3	no	7.632	3.057	EPSD	ICGC	7.604	Loss
AGC_PKC_PKCd_PRKCD_ST	P11413	G6PD	Q05655	PRKCD	S123	N122K	122	Missense	proximal	-1	no	7.632	7.813	EPSD	ICGC;COSMIC	7.604	Up-regulation
AGC_PKC_PKCd_PRKCD_ST	P11413	G6PD	Q05655	PRKCD	S123	M125I	125	Missense	proximal	2	no	7.632	6.828	EPSD	ICGC	7.604	Loss
AGC_PKC_PKCd_PRKCD_ST	P11413	G6PD	Q05655	PRKCD	S180	G174E	174	Missense	distal	-6	no	9.415	9.392	EPSD	ICGC	7.604	Down-regulation
AGC_PKC_PKCd_PRKCD_ST	P11413	G6PD	Q05655	PRKCD	S180	G174R	174	Missense	distal	-6	no	9.415	9.023	EPSD	ICGC;COSMIC	7.604	Down-regulation
AGC_PKC_PKCd_PRKCD_ST	P11413	G6PD	Q05655	PRKCD	S180	R182L	182	Missense	proximal	2	no	9.415	2.537	EPSD	ICGC;COSMIC	7.604	Loss
AGC_PKC_PKCd_PRKCD_ST	P11413	G6PD	Q05655	PRKCD	S180	S180F	180	Missense	central	0	yes	9.415	0.000	EPSD	ICGC;COSMIC	7.604	Loss
AGC_PKC_PKCd_PRKCD_ST	P11413	G6PD	Q05655	PRKCD	S180	D176N	176	Missense	distal	-4	no	9.415	9.440	EPSD	ICGC;COSMIC	7.604	Up-regulation
AGC_PKC_PKCd_PRKCD_ST	P11413	G6PD	Q05655	PRKCD	S184	S188F	188	Missense	distal	4	no	9.137	8.992	EPSD	ICGC;COSMIC	7.604	Down-regulation
AGC_PKC_PKCd_PRKCD_ST	P11413	G6PD	Q05655	PRKCD	S184	R182L	182	Missense	proximal	-2	no	9.137	3.004	EPSD	ICGC;COSMIC	7.604	Loss
AGC_PKC_PKCd_PRKCD_ST	P11413	G6PD	Q05655	PRKCD	S184	S180F	180	Missense	distal	-4	no	9.137	9.268	EPSD	ICGC;COSMIC	7.604	Up-regulation
AGC_PKC_PKCd_PRKCD_ST	P11413	G6PD	Q05655	PRKCD	S184	L190M	190	Missense	distal	6	no	9.137	9.133	EPSD	ICGC;COSMIC	7.604	Down-regulation
AGC_PKC_PKCd_PRKCD_ST	P11413	G6PD	Q05655	PRKCD	T490	R487Q	487	Missense	distal	-3	no	7.652	2.495	EPSD	ICGC;COSMIC	7.604	Loss
AGC_PKC_PKCd_PRKCD_ST	P11413	G6PD	Q05655	PRKCD	T490	T490K	490	Missense	central	0	yes	7.652	0.000	EPSD	ICGC	7.604	Loss
AGC_PKC_PKCd_PRKCD_ST	P11413	G6PD	Q05655	PRKCD	T490	G485V	485	Missense	distal	-5	no	7.652	7.636	EPSD	ICGC;COSMIC	7.604	Down-regulation
AGC_PKC_PKCd_PRKCD_ST	Q00535	CDK5	Q05655	PRKCD	T77	F82L	82	Missense	distal	5	no	8.760	8.781	PhosphoSitePlus	ICGC	7.604	Up-regulation
AGC_PKC_PKCd_PRKCD_ST	P10588	NR2F6	Q05655	PRKCD	S32	E29K	29	Missense	distal	-3	no	3.426	7.812	EPSD	ICGC;COSMIC	7.604	Gain
AGC_PKC_PKCd_PRKCD_ST	P10588	NR2F6	Q05655	PRKCD	S83	R86L	86	Missense	distal	3	no	15.568	14.424	PhosphoSitePlus	ICGC;COSMIC	7.604	Down-regulation
AGC_PKC_PKCd_PRKCD_ST	P10588	NR2F6	Q05655	PRKCD	S345	Q342R	342	Missense	distal	-3	no	2.564	7.722	EPSD	ICGC;COSMIC	7.604	Gain
AGC_PKC_PKCd_PRKCD_ST	P40189	IL6ST	Q05655	PRKCD	S461	A464E	464	Missense	distal	3	no	9.153	8.901	EPSD	ICGC	7.604	Down-regulation
AGC_PKC_PKCd_PRKCD_ST	P40189	IL6ST	Q05655	PRKCD	T909	G914C	914	Missense	distal	5	no	7.741	7.620	EPSD	ICGC;COSMIC	7.604	Down-regulation
AGC_PKC_PKCd_PRKCD_ST	P23396	RPS3	Q05655	PRKCD	S6	V3L	3	Missense	distal	-3	no	9.892	9.506	PhosphoSitePlus;EPSD	ICGC;COSMIC	7.604	Down-regulation
AGC_PKC_PKCd_PRKCD_ST	P23396	RPS3	Q05655	PRKCD	S6	A13S	13	Missense	distal	7	no	9.892	9.918	PhosphoSitePlus;EPSD	ICGC	7.604	Up-regulation
AGC_PKC_PKCd_PRKCD_ST	P23396	RPS3	Q05655	PRKCD	S104	A102D	102	Missense	proximal	-2	no	8.374	7.632	EPSD	ICGC;COSMIC	7.604	Down-regulation
AGC_PKC_PKCd_PRKCD_ST	O14939	PLD2	Q05655	PRKCD	T76	E73K	73	Missense	distal	-3	no	3.226	7.611	EPSD	ICGC;COSMIC;GDSC;CCLE	7.604	Gain
AGC_PKC_PKCd_PRKCD_ST	O14939	PLD2	Q05655	PRKCD	T99	D95G	95	Missense	distal	-4	no	8.289	8.312	EPSD	ICGC;COSMIC	7.604	Up-regulation
AGC_PKC_PKCd_PRKCD_ST	O14939	PLD2	Q05655	PRKCD	S155	R149P	149	Missense	distal	-6	no	8.536	8.813	EPSD	ICGC;COSMIC	7.604	Up-regulation
AGC_PKC_PKCd_PRKCD_ST	O14939	PLD2	Q05655	PRKCD	S213	G207R	207	Missense	distal	-6	no	14.005	13.613	EPSD	ICGC;COSMIC	7.604	Down-regulation
AGC_PKC_PKCd_PRKCD_ST	O14939	PLD2	Q05655	PRKCD	S213	R210W	210	Missense	distal	-3	no	14.005	8.708	EPSD	ICGC;COSMIC;GDSC;CCLE	7.604	Down-regulation
AGC_PKC_PKCd_PRKCD_ST	O14939	PLD2	Q05655	PRKCD	S213	R217C	217	Missense	distal	4	no	14.005	13.208	EPSD	ICGC	7.604	Down-regulation
AGC_PKC_PKCd_PRKCD_ST	O14939	PLD2	Q05655	PRKCD	T274	V280M	280	Missense	distal	6	no	13.611	13.613	EPSD	ICGC;COSMIC	7.604	Up-regulation
AGC_PKC_PKCd_PRKCD_ST	O14939	PLD2	Q05655	PRKCD	S416	G414D	414	Missense	proximal	-2	no	7.863	8.075	EPSD	ICGC;COSMIC	7.604	Up-regulation
AGC_PKC_PKCd_PRKCD_ST	O14939	PLD2	Q05655	PRKCD	S493	P489L	489	Missense	distal	-4	no	9.471	9.610	EPSD	ICGC;COSMIC	7.604	Up-regulation
AGC_PKC_PKCd_PRKCD_ST	O14939	PLD2	Q05655	PRKCD	S493	P489S	489	Missense	distal	-4	no	9.471	9.449	EPSD	ICGC;COSMIC;GDSC;CCLE	7.604	Down-regulation
AGC_PKC_PKCd_PRKCD_ST	O14939	PLD2	Q05655	PRKCD	S814	G821S	821	Missense	distal	7	no	10.890	10.935	EPSD	ICGC;COSMIC	7.604	Up-regulation
AGC_PKC_PKCd_PRKCD_ST	O95817	BAG3	Q05655	PRKCD	S136	R139W	139	Missense	distal	3	no	8.017	6.595	EPSD	ICGC;COSMIC	7.604	Loss
AGC_PKC_PKCd_PRKCD_ST	O95817	BAG3	Q05655	PRKCD	S136	R139Q	139	Missense	distal	3	no	8.017	6.940	EPSD	ICGC;COSMIC	7.604	Loss
AGC_PKC_PKCd_PRKCD_ST	O95817	BAG3	Q05655	PRKCD	S136	M141I	141	Missense	distal	5	no	8.017	7.943	EPSD	ICGC;COSMIC	7.604	Down-regulation
AGC_PKC_PKCd_PRKCD_ST	O95817	BAG3	Q05655	PRKCD	S136	E143V	143	Missense	distal	7	no	8.017	7.998	EPSD	ICGC;COSMIC	7.604	Down-regulation
AGC_PKC_PKCd_PRKCD_ST	O95817	BAG3	Q05655	PRKCD	S136	S134F	134	Missense	proximal	-2	no	8.017	7.494	EPSD	ICGC;COSMIC	7.604	Loss
AGC_PKC_PKCd_PRKCD_ST	O95817	BAG3	Q05655	PRKCD	S173	P174Q	174	Missense	proximal	1	no	8.090	8.034	EPSD	ICGC;COSMIC	7.604	Down-regulation
AGC_PKC_PKCd_PRKCD_ST	O95817	BAG3	Q05655	PRKCD	S191	G197C	197	Missense	distal	6	no	9.348	9.331	EPSD	ICGC;COSMIC	7.604	Down-regulation
AGC_PKC_PKCd_PRKCD_ST	O95817	BAG3	Q05655	PRKCD	S191	G192V	192	Missense	proximal	1	no	9.348	9.358	EPSD	ICGC	7.604	Up-regulation
AGC_PKC_PKCd_PRKCD_ST	O95817	BAG3	Q05655	PRKCD	S191	G192S	192	Missense	proximal	1	no	9.348	9.454	EPSD	ICGC;GDSC	7.604	Up-regulation
AGC_PKC_PKCd_PRKCD_ST	O95817	BAG3	Q05655	PRKCD	S191	S185L	185	Missense	distal	-6	no	9.348	9.593	EPSD	ICGC;COSMIC;GDSC	7.604	Up-regulation
AGC_PKC_PKCd_PRKCD_ST	O95817	BAG3	Q05655	PRKCD	S195	G192S	192	Missense	distal	-3	no	6.994	7.628	EPSD	ICGC;GDSC	7.604	Gain
AGC_PKC_PKCd_PRKCD_ST	O95817	BAG3	Q05655	PRKCD	S264	A262V	262	Missense	proximal	-2	no	8.309	7.677	EPSD	ICGC	7.604	Down-regulation
AGC_PKC_PKCd_PRKCD_ST	O95817	BAG3	Q05655	PRKCD	S264	R261L	261	Missense	distal	-3	no	8.309	3.122	EPSD	ICGC	7.604	Loss
AGC_PKC_PKCd_PRKCD_ST	O95817	BAG3	Q05655	PRKCD	S269	A262V	262	Missense	distal	-7	no	7.782	7.776	EPSD	ICGC	7.604	Down-regulation
AGC_PKC_PKCd_PRKCD_ST	O95817	BAG3	Q05655	PRKCD	S269	S274L	274	Missense	distal	5	no	7.782	7.592	EPSD	ICGC	7.604	Loss
AGC_PKC_PKCd_PRKCD_ST	O95817	BAG3	Q05655	PRKCD	S279	S274L	274	Missense	distal	-5	no	9.528	9.373	EPSD	ICGC	7.604	Down-regulation
AGC_PKC_PKCd_PRKCD_ST	O95817	BAG3	Q05655	PRKCD	S279	T285M	285	Missense	distal	6	no	9.528	9.501	EPSD	ICGC;COSMIC	7.604	Down-regulation
AGC_PKC_PKCd_PRKCD_ST	O95817	BAG3	Q05655	PRKCD	S284	T285M	285	Missense	proximal	1	no	8.686	8.610	EPSD	ICGC;COSMIC	7.604	Down-regulation
AGC_PKC_PKCd_PRKCD_ST	O95817	BAG3	Q05655	PRKCD	S386	A391S	391	Missense	distal	5	no	8.821	8.957	EPSD	ICGC	7.604	Up-regulation
AGC_PKC_PKCd_PRKCD_ST	O95817	BAG3	Q05655	PRKCD	S386	P387L	387	Missense	proximal	1	no	8.821	8.746	EPSD	ICGC;COSMIC	7.604	Down-regulation
AGC_PKC_PKCd_PRKCD_ST	P29353	SHC1	Q05655	PRKCD	S80	R77H	77	Missense	distal	-3	no	7.765	3.510	EPSD	ICGC	7.604	Loss
AGC_PKC_PKCd_PRKCD_ST	P29353	SHC1	Q05655	PRKCD	S80	R77C	77	Missense	distal	-3	no	7.765	2.445	EPSD	ICGC;COSMIC;GDSC;CCLE	7.604	Loss
AGC_PKC_PKCd_PRKCD_ST	P29353	SHC1	Q05655	PRKCD	S80	A87V	87	Missense	distal	7	no	7.765	7.727	EPSD	ICGC;COSMIC	7.604	Down-regulation
AGC_PKC_PKCd_PRKCD_ST	P29353	SHC1	Q05655	PRKCD	S139	P144S	144	Missense	distal	5	no	9.770	9.738	EPSD	ICGC;COSMIC	7.604	Down-regulation
AGC_PKC_PKCd_PRKCD_ST	P29353	SHC1	Q05655	PRKCD	S139	R136S	136	Missense	distal	-3	no	9.770	5.195	EPSD	ICGC	7.604	Loss
AGC_PKC_PKCd_PRKCD_ST	P29353	SHC1	Q05655	PRKCD	S139	H137Q	137	Missense	proximal	-2	no	9.770	9.311	EPSD	ICGC	7.604	Down-regulation
AGC_PKC_PKCd_PRKCD_ST	P29353	SHC1	Q05655	PRKCD	S139	R136L	136	Missense	distal	-3	no	9.770	4.584	EPSD	ICGC;COSMIC	7.604	Loss
AGC_PKC_PKCd_PRKCD_ST	Q15717	ELAVL1	Q05655	PRKCD	S94	P98L	98	Missense	distal	4	no	7.889	7.684	EPSD	ICGC;COSMIC	7.604	Down-regulation
AGC_PKC_PKCd_PRKCD_ST	Q15717	ELAVL1	Q05655	PRKCD	S94	R97H	97	Missense	distal	3	no	7.889	7.001	EPSD	ICGC	7.604	Loss
AGC_PKC_PKCd_PRKCD_ST	Q15717	ELAVL1	Q05655	PRKCD	S94	Y95C	95	Missense	proximal	1	no	7.889	7.887	EPSD	ICGC	7.604	Down-regulation
AGC_PKC_PKCd_PRKCD_ST	Q15717	ELAVL1	Q05655	PRKCD	S99	P98L	98	Missense	proximal	-1	no	7.638	7.562	EPSD	ICGC;COSMIC	7.604	Loss
AGC_PKC_PKCd_PRKCD_ST	Q15717	ELAVL1	Q05655	PRKCD	S99	R97H	97	Missense	proximal	-2	no	7.638	2.662	EPSD	ICGC	7.604	Loss
AGC_PKC_PKCd_PRKCD_ST	Q15717	ELAVL1	Q05655	PRKCD	S99	Y95C	95	Missense	distal	-4	no	7.638	7.619	EPSD	ICGC	7.604	Down-regulation
AGC_PKC_PKCd_PRKCD_ST	Q15717	ELAVL1	Q05655	PRKCD	S100	P98L	98	Missense	proximal	-2	no	7.665	5.995	EPSD	ICGC;COSMIC	7.604	Loss
AGC_PKC_PKCd_PRKCD_ST	Q15717	ELAVL1	Q05655	PRKCD	S100	R97H	97	Missense	distal	-3	no	7.665	3.410	EPSD	ICGC	7.604	Loss
AGC_PKC_PKCd_PRKCD_ST	Q15717	ELAVL1	Q05655	PRKCD	T118	G112R	112	Missense	distal	-6	no	8.577	8.185	EPSD	ICGC;COSMIC	7.604	Down-regulation
AGC_PKC_PKCd_PRKCD_ST	Q15717	ELAVL1	Q05655	PRKCD	T118	R115W	115	Missense	distal	-3	no	8.577	3.281	EPSD	ICGC;COSMIC;GDSC;CCLE	7.604	Loss
AGC_PKC_PKCd_PRKCD_ST	Q15717	ELAVL1	Q05655	PRKCD	T118	T116N	116	Missense	proximal	-2	no	8.577	8.565	EPSD	ICGC	7.604	Down-regulation
AGC_PKC_PKCd_PRKCD_ST	Q15717	ELAVL1	Q05655	PRKCD	T118	T118N	118	Missense	central	0	yes	8.577	0.000	EPSD	ICGC	7.604	Loss
AGC_PKC_PKCd_PRKCD_ST	Q15717	ELAVL1	Q05655	PRKCD	T118	G112W	112	Missense	distal	-6	no	8.577	8.777	EPSD	ICGC;COSMIC	7.604	Up-regulation
AGC_PKC_PKCd_PRKCD_ST	Q15717	ELAVL1	Q05655	PRKCD	T118	Q119K	119	Missense	proximal	1	no	8.577	8.725	EPSD	ICGC;COSMIC	7.604	Up-regulation
AGC_PKC_PKCd_PRKCD_ST	Q15717	ELAVL1	Q05655	PRKCD	T118	L113H	113	Missense	distal	-5	no	8.577	8.671	EPSD	ICGC	7.604	Up-regulation
AGC_PKC_PKCd_PRKCD_ST	Q15717	ELAVL1	Q05655	PRKCD	S221	A215V	215	Missense	distal	-6	no	8.144	8.268	EPSD;PhosphoSitePlus	ICGC;COSMIC	7.604	Up-regulation
AGC_PKC_PKCd_PRKCD_ST	Q15717	ELAVL1	Q05655	PRKCD	S221	S221F	221	Missense	central	0	yes	8.144	0.000	EPSD;PhosphoSitePlus	ICGC;COSMIC	7.604	Loss
AGC_PKC_PKCd_PRKCD_ST	Q15717	ELAVL1	Q05655	PRKCD	S221	G224C	224	Missense	distal	3	no	8.144	8.006	EPSD;PhosphoSitePlus	ICGC	7.604	Down-regulation
AGC_PKC_PKCd_PRKCD_ST	Q15717	ELAVL1	Q05655	PRKCD	S221	F218L	218	Missense	distal	-3	no	8.144	7.481	EPSD;PhosphoSitePlus	ICGC	7.604	Loss
AGC_PKC_PKCd_PRKCD_ST	Q15717	ELAVL1	Q05655	PRKCD	S221	Q216R	216	Missense	distal	-5	no	8.144	8.494	EPSD;PhosphoSitePlus	ICGC;COSMIC	7.604	Up-regulation
AGC_PKC_PKCd_PRKCD_ST	Q15717	ELAVL1	Q05655	PRKCD	S318	H325N	325	Missense	distal	7	no	9.303	9.277	PhosphoSitePlus;EPSD	ICGC	7.604	Down-regulation
AGC_PKC_PKCd_PRKCD_ST	Q15717	ELAVL1	Q05655	PRKCD	S318	H325Q	325	Missense	distal	7	no	9.303	9.298	PhosphoSitePlus;EPSD	ICGC	7.604	Down-regulation
AGC_PKC_PKCd_PRKCD_ST	Q15717	ELAVL1	Q05655	PRKCD	S318	Q316K	316	Missense	proximal	-2	no	9.303	13.492	PhosphoSitePlus;EPSD	ICGC	7.604	Up-regulation
AGC_PKC_PKCd_PRKCD_ST	O00165	HAX1	Q05655	PRKCD	S53	Q55H	55	Missense	proximal	2	no	7.140	8.369	EPSD	ICGC	7.604	Gain
AGC_PKC_PKCd_PRKCD_ST	P35222	CTNNB1	Q05655	PRKCD	T547	R542C	542	Missense	distal	-5	no	10.676	10.199	EPSD	ICGC;COSMIC	7.604	Down-regulation
AGC_PKC_PKCd_PRKCD_ST	P35222	CTNNB1	Q05655	PRKCD	S715	R710H	710	Missense	distal	-5	no	10.409	10.073	PhosphoSitePlus	ICGC;COSMIC	7.604	Down-regulation
AGC_PKC_PKCd_PRKCD_ST	P49840	GSK3A	Q05655	PRKCD	S97	D96E	96	Missense	proximal	-1	no	13.735	13.717	EPSD	ICGC;COSMIC	7.604	Down-regulation
AGC_PKC_PKCd_PRKCD_ST	P49840	GSK3A	Q05655	PRKCD	S97	R95G	95	Missense	proximal	-2	no	13.735	7.972	EPSD	ICGC;COSMIC	7.604	Down-regulation
AGC_PKC_PKCd_PRKCD_ST	P49840	GSK3A	Q05655	PRKCD	S97	G98R	98	Missense	proximal	1	no	13.735	13.937	EPSD	ICGC	7.604	Up-regulation
AGC_PKC_PKCd_PRKCD_ST	P49840	GSK3A	Q05655	PRKCD	S97	V103A	103	Missense	distal	6	no	13.735	13.753	EPSD	ICGC;COSMIC	7.604	Up-regulation
AGC_PKC_PKCd_PRKCD_ST	P49840	GSK3A	Q05655	PRKCD	T101	G98R	98	Missense	distal	-3	no	4.972	10.180	EPSD	ICGC	7.604	Gain
AGC_PKC_PKCd_PRKCD_ST	Q96C90	PPP1R14B	Q05655	PRKCD	T57	R52S	52	Missense	distal	-5	no	8.969	8.694	PhosphoSitePlus	ICGC	7.604	Down-regulation
AGC_PKC_PKCd_PRKCD_ST	P30273	FCER1G	Q05655	PRKCD	S69	T75I	75	Missense	distal	6	no	9.696	9.663	PhosphoSitePlus	ICGC;COSMIC	7.604	Down-regulation
AGC_PKC_PKCd_PRKCD_ST	P30273	FCER1G	Q05655	PRKCD	S69	N72K	72	Missense	distal	3	no	9.696	10.831	PhosphoSitePlus	ICGC;COSMIC	7.604	Up-regulation
AGC_PKC_PKCd_PRKCD_ST	P30273	FCER1G	Q05655	PRKCD	S69	V64F	64	Missense	distal	-5	no	9.696	9.742	PhosphoSitePlus	ICGC	7.604	Up-regulation
AGC_PKC_PKCd_PRKCD_ST	P30273	FCER1G	Q05655	PRKCD	S69	E74A	74	Missense	distal	5	no	9.696	9.708	PhosphoSitePlus	ICGC;COSMIC	7.604	Up-regulation
AGC_PKC_PKCd_PRKCD_ST	P30273	FCER1G	Q05655	PRKCD	S69	N72Y	72	Missense	distal	3	no	9.696	9.490	PhosphoSitePlus	ICGC;COSMIC	7.604	Down-regulation
AGC_PKC_PKCd_PRKCD_ST	P49841	GSK3B	Q05655	PRKCD	T7	A11S	11	Missense	distal	4	no	7.670	7.737	EPSD	ICGC;COSMIC	7.604	Up-regulation
AGC_PKC_PKCd_PRKCD_ST	P49841	GSK3B	Q05655	PRKCD	S9	A11S	11	Missense	proximal	2	no	8.872	8.032	PhosphoSitePlus	ICGC;COSMIC	7.604	Down-regulation
AGC_PKC_PKCd_PRKCD_ST	P49841	GSK3B	Q05655	PRKCD	S13	A11S	11	Missense	proximal	-2	no	9.596	9.558	EPSD	ICGC;COSMIC	7.604	Down-regulation
AGC_PKC_PKCd_PRKCD_ST	P49841	GSK3B	Q05655	PRKCD	S55	E53K	53	Missense	proximal	-2	no	2.741	7.722	EPSD	ICGC;COSMIC	7.604	Gain
AGC_PKC_PKCd_PRKCD_ST	P49841	GSK3B	Q05655	PRKCD	S147	P154H	154	Missense	distal	7	no	8.102	8.108	EPSD	ICGC;COSMIC	7.604	Up-regulation
AGC_PKC_PKCd_PRKCD_ST	P49841	GSK3B	Q05655	PRKCD	S147	A149D	149	Missense	proximal	2	no	8.102	6.860	EPSD	ICGC	7.604	Loss
AGC_PKC_PKCd_PRKCD_ST	P49841	GSK3B	Q05655	PRKCD	S147	T152R	152	Missense	distal	5	no	8.102	8.427	EPSD	ICGC;COSMIC	7.604	Up-regulation
AGC_PKC_PKCd_PRKCD_ST	P49841	GSK3B	Q05655	PRKCD	S147	Q151R	151	Missense	distal	4	no	8.102	8.690	EPSD	ICGC;COSMIC	7.604	Up-regulation
AGC_PKC_PKCd_PRKCD_ST	P49841	GSK3B	Q05655	PRKCD	T408	G406R	406	Missense	proximal	-2	no	5.699	11.463	EPSD	ICGC;COSMIC	7.604	Gain
AGC_PKC_PKCd_PRKCD_ST	P40763	STAT3	Q05655	PRKCD	T412	E415V	415	Missense	distal	3	no	11.390	11.409	EPSD	ICGC;COSMIC	7.604	Up-regulation
AGC_PKC_PKCd_PRKCD_ST	P40763	STAT3	Q05655	PRKCD	T412	E415K	415	Missense	distal	3	no	11.390	12.571	EPSD	ICGC;COSMIC	7.604	Up-regulation
AGC_PKC_PKCd_PRKCD_ST	P40763	STAT3	Q05655	PRKCD	S691	P689T	689	Missense	proximal	-2	no	7.798	6.298	EPSD	ICGC	7.604	Loss
AGC_PKC_PKCd_PRKCD_ST	P40763	STAT3	Q05655	PRKCD	S691	S691C	691	Missense	central	0	yes	7.798	0.000	EPSD	ICGC;COSMIC	7.604	Loss
AGC_PKC_PKCd_PRKCD_ST	P40763	STAT3	Q05655	PRKCD	S691	R688W	688	Missense	distal	-3	no	7.798	2.501	EPSD	ICGC;COSMIC;GDSC;CCLE	7.604	Loss
AGC_PKC_PKCd_PRKCD_ST	P40763	STAT3	Q05655	PRKCD	S727	L724P	724	Missense	distal	-3	no	8.961	9.904	PhosphoSitePlus	ICGC;COSMIC	7.604	Up-regulation
AGC_PKC_PKCd_PRKCD_ST	P40763	STAT3	Q05655	PRKCD	S727	S727P	727	Missense	central	0	yes	8.961	0.000	PhosphoSitePlus	ICGC	7.604	Loss
AGC_PKC_PKCd_PRKCD_ST	P40763	STAT3	Q05655	PRKCD	S727	L734S	734	Missense	distal	7	no	8.961	9.020	PhosphoSitePlus	ICGC;COSMIC	7.604	Up-regulation
AGC_PKC_PKCd_PRKCD_ST	O00429	DNM1L	Q05655	PRKCD	T78	D74N	74	Missense	distal	-4	no	9.612	9.638	EPSD	ICGC	7.604	Up-regulation
AGC_PKC_PKCd_PRKCD_ST	O00429	DNM1L	Q05655	PRKCD	T78	D74E	74	Missense	distal	-4	no	9.612	9.617	EPSD	ICGC;COSMIC	7.604	Up-regulation
AGC_PKC_PKCd_PRKCD_ST	O00429	DNM1L	Q05655	PRKCD	T79	D74N	74	Missense	distal	-5	no	8.492	8.469	EPSD	ICGC	7.604	Down-regulation
AGC_PKC_PKCd_PRKCD_ST	O00429	DNM1L	Q05655	PRKCD	T79	D74E	74	Missense	distal	-5	no	8.492	8.490	EPSD	ICGC;COSMIC	7.604	Down-regulation
AGC_PKC_PKCd_PRKCD_ST	O00429	DNM1L	Q05655	PRKCD	S596	A598D	598	Missense	proximal	2	no	8.326	7.084	EPSD	ICGC;COSMIC	7.604	Loss
AGC_PKC_PKCd_PRKCD_ST	Q09472	EP300	Q05655	PRKCD	S12	P8S	8	Missense	distal	-4	no	11.076	11.055	EPSD	ICGC;COSMIC	7.604	Down-regulation
AGC_PKC_PKCd_PRKCD_ST	Q09472	EP300	Q05655	PRKCD	S12	S12P	12	Missense	central	0	yes	11.076	0.000	EPSD	ICGC;COSMIC	7.604	Loss
AGC_PKC_PKCd_PRKCD_ST	Q09472	EP300	Q05655	PRKCD	S19	S24L	24	Missense	distal	5	no	9.230	9.040	EPSD	ICGC;COSMIC	7.604	Down-regulation
AGC_PKC_PKCd_PRKCD_ST	Q09472	EP300	Q05655	PRKCD	S20	S24L	24	Missense	distal	4	no	8.222	8.055	EPSD	ICGC;COSMIC	7.604	Down-regulation
AGC_PKC_PKCd_PRKCD_ST	Q09472	EP300	Q05655	PRKCD	S89	L93F	93	Missense	distal	4	no	9.743	9.765	PhosphoSitePlus	ICGC	7.604	Up-regulation
AGC_PKC_PKCd_PRKCD_ST	Q09472	EP300	Q05655	PRKCD	S395	I399V	399	Missense	distal	4	no	8.066	8.132	EPSD	ICGC;COSMIC	7.604	Up-regulation
AGC_PKC_PKCd_PRKCD_ST	Q09472	EP300	Q05655	PRKCD	S395	V390G	390	Missense	distal	-5	no	8.066	8.082	EPSD	ICGC;COSMIC	7.604	Up-regulation
AGC_PKC_PKCd_PRKCD_ST	Q09472	EP300	Q05655	PRKCD	S1044	P1039S	1039	Missense	distal	-5	no	8.371	8.380	EPSD	ICGC;COSMIC	7.604	Up-regulation
AGC_PKC_PKCd_PRKCD_ST	Q09472	EP300	Q05655	PRKCD	T1135	A1128T	1128	Missense	distal	-7	no	12.232	12.234	EPSD	ICGC	7.604	Up-regulation
AGC_PKC_PKCd_PRKCD_ST	Q09472	EP300	Q05655	PRKCD	T1135	Y1131N	1131	Missense	distal	-4	no	12.232	12.165	EPSD	ICGC;COSMIC	7.604	Down-regulation
AGC_PKC_PKCd_PRKCD_ST	Q09472	EP300	Q05655	PRKCD	S1643	S1650Y	1650	Missense	distal	7	no	9.055	8.982	EPSD	ICGC;COSMIC;CCLE	7.604	Down-regulation
AGC_PKC_PKCd_PRKCD_ST	Q09472	EP300	Q05655	PRKCD	S1643	A1647S	1647	Missense	distal	4	no	9.055	9.122	EPSD	ICGC	7.604	Up-regulation
AGC_PKC_PKCd_PRKCD_ST	Q09472	EP300	Q05655	PRKCD	S1730	D1729N	1729	Missense	proximal	-1	no	7.716	7.690	EPSD	ICGC;COSMIC	7.604	Down-regulation
AGC_PKC_PKCd_PRKCD_ST	Q09472	EP300	Q05655	PRKCD	S1734	D1729N	1729	Missense	distal	-5	no	13.068	13.045	EPSD	ICGC;COSMIC	7.604	Down-regulation
AGC_PKC_PKCd_PRKCD_ST	Q09472	EP300	Q05655	PRKCD	S1734	Q1740K	1740	Missense	distal	6	no	13.068	13.117	EPSD	ICGC;COSMIC	7.604	Up-regulation
AGC_PKC_PKCd_PRKCD_ST	Q01543	FLI1	Q05655	PRKCD	S79	V81A	81	Missense	proximal	2	no	8.546	9.694	EPSD	ICGC	7.604	Up-regulation
AGC_PKC_PKCd_PRKCD_ST	Q01543	FLI1	Q05655	PRKCD	S79	P80L	80	Missense	proximal	1	no	8.546	8.472	EPSD	ICGC;COSMIC;GDSC;CCLE	7.604	Down-regulation
AGC_PKC_PKCd_PRKCD_ST	Q01543	FLI1	Q05655	PRKCD	S215	D209Y	209	Missense	distal	-6	no	13.714	13.828	EPSD	ICGC	7.604	Up-regulation
AGC_PKC_PKCd_PRKCD_ST	P08581	MET	Q05655	PRKCD	S985	R987G	987	Missense	proximal	2	no	12.233	5.902	PhosphoSitePlus	ICGC;COSMIC	7.604	Loss
AGC_PKC_PKCd_PRKCD_ST	P08581	MET	Q05655	PRKCD	S985	L983H	983	Missense	proximal	-2	no	12.233	13.391	PhosphoSitePlus	ICGC;COSMIC	7.604	Up-regulation
AGC_PKC_PKCd_PRKCD_ST	P08581	MET	Q05655	PRKCD	S985	H979Y	979	Missense	distal	-6	no	12.233	12.400	PhosphoSitePlus	ICGC;COSMIC	7.604	Up-regulation
AGC_PKC_PKCd_PRKCD_ST	P08581	MET	Q05655	PRKCD	S985	R982M	982	Missense	distal	-3	no	12.233	7.411	PhosphoSitePlus	ICGC;COSMIC	7.604	Loss
AGC_PKC_PKCd_PRKCD_ST	P08581	MET	Q05655	PRKCD	S990	E994K	994	Missense	distal	4	no	7.432	8.027	EPSD	ICGC;COSMIC	7.604	Gain
AGC_PKC_PKCd_PRKCD_ST	P08581	MET	Q05655	PRKCD	T1261	Q1258K	1258	Missense	distal	-3	no	8.120	12.243	EPSD	ICGC;COSMIC	7.604	Up-regulation
AGC_PKC_PKCd_PRKCD_ST	Q9UQ80	PA2G4	Q05655	PRKCD	T261	F265L	265	Missense	distal	4	no	9.778	9.757	EPSD	ICGC;COSMIC	7.604	Down-regulation
AGC_PKC_PKCd_PRKCD_ST	Q9UQ80	PA2G4	Q05655	PRKCD	T261	E268K	268	Missense	distal	7	no	9.778	9.916	EPSD	ICGC;COSMIC	7.604	Up-regulation
AGC_PKC_PKCd_PRKCD_ST	Q9UQ80	PA2G4	Q05655	PRKCD	S262	F265L	265	Missense	distal	3	no	7.689	7.621	EPSD	ICGC;COSMIC	7.604	Down-regulation
AGC_PKC_PKCd_PRKCD_ST	Q9UQ80	PA2G4	Q05655	PRKCD	S262	E268G	268	Missense	distal	6	no	7.689	7.683	EPSD	ICGC;COSMIC	7.604	Down-regulation
AGC_PKC_PKCd_PRKCD_ST	Q9UQ80	PA2G4	Q05655	PRKCD	S262	E268K	268	Missense	distal	6	no	7.689	7.744	EPSD	ICGC;COSMIC	7.604	Up-regulation
AGC_PKC_PKCd_PRKCD_ST	Q9UQ80	PA2G4	Q05655	PRKCD	S363	Q367K	367	Missense	distal	4	no	10.325	10.906	EPSD	ICGC;COSMIC	7.604	Up-regulation
AGC_PKC_PKCd_PRKCD_ST	Q9UQ80	PA2G4	Q05655	PRKCD	T366	Q367K	367	Missense	proximal	1	no	12.737	12.885	EPSD	ICGC;COSMIC	7.604	Up-regulation
AGC_PKC_PKCd_PRKCD_ST	Q9UQ80	PA2G4	Q05655	PRKCD	S375	A378T	378	Missense	distal	3	no	11.600	11.524	EPSD	ICGC;COSMIC	7.604	Down-regulation
AGC_PKC_PKCd_PRKCD_ST	P04040	CAT	Q05655	PRKCD	S114	A110S	110	Missense	distal	-4	no	8.515	8.433	EPSD	ICGC;COSMIC	7.604	Down-regulation
AGC_PKC_PKCd_PRKCD_ST	P04040	CAT	Q05655	PRKCD	S114	V111F	111	Missense	distal	-3	no	8.515	8.793	EPSD	ICGC	7.604	Up-regulation
AGC_PKC_PKCd_PRKCD_ST	P04040	CAT	Q05655	PRKCD	S114	G118V	118	Missense	distal	4	no	8.515	8.491	EPSD	ICGC;COSMIC	7.604	Down-regulation
AGC_PKC_PKCd_PRKCD_ST	P04040	CAT	Q05655	PRKCD	S114	R112Q	112	Missense	proximal	-2	no	8.515	3.081	EPSD	ICGC;COSMIC	7.604	Loss
AGC_PKC_PKCd_PRKCD_ST	P04040	CAT	Q05655	PRKCD	T115	A110S	110	Missense	distal	-5	no	8.076	8.144	EPSD	ICGC;COSMIC	7.604	Up-regulation
AGC_PKC_PKCd_PRKCD_ST	P04040	CAT	Q05655	PRKCD	T115	V111F	111	Missense	distal	-4	no	8.076	8.039	EPSD	ICGC	7.604	Down-regulation
AGC_PKC_PKCd_PRKCD_ST	P04040	CAT	Q05655	PRKCD	T115	G118V	118	Missense	distal	3	no	8.076	8.057	EPSD	ICGC;COSMIC	7.604	Down-regulation
AGC_PKC_PKCd_PRKCD_ST	P04040	CAT	Q05655	PRKCD	T115	R112Q	112	Missense	distal	-3	no	8.076	2.918	EPSD	ICGC;COSMIC	7.604	Loss
AGC_PKC_PKCd_PRKCD_ST	P04040	CAT	Q05655	PRKCD	S167	P162S	162	Missense	distal	-5	no	8.389	8.398	PhosphoSitePlus	ICGC	7.604	Up-regulation
AGC_PKC_PKCd_PRKCD_ST	P04040	CAT	Q05655	PRKCD	S167	Q173R	173	Missense	distal	6	no	8.389	8.435	PhosphoSitePlus	ICGC;COSMIC	7.604	Up-regulation
AGC_PKC_PKCd_PRKCD_ST	O15350	TP73	Q05655	PRKCD	S235	G232S	232	Missense	distal	-3	no	7.238	7.872	EPSD	ICGC;COSMIC	7.604	Gain
AGC_PKC_PKCd_PRKCD_ST	O15350	TP73	Q05655	PRKCD	S289	I294L	294	Missense	distal	5	no	8.553	8.696	PhosphoSitePlus	ICGC;COSMIC	7.604	Up-regulation
AGC_PKC_PKCd_PRKCD_ST	O15350	TP73	Q05655	PRKCD	S326	G323R	323	Missense	distal	-3	no	9.334	14.543	EPSD	ICGC;COSMIC	7.604	Up-regulation
AGC_PKC_PKCd_PRKCD_ST	O15350	TP73	Q05655	PRKCD	S326	K331N	331	Missense	distal	5	no	9.334	8.826	EPSD	ICGC	7.604	Down-regulation
AGC_PKC_PKCd_PRKCD_ST	O15350	TP73	Q05655	PRKCD	S333	V337I	337	Missense	distal	4	no	7.670	7.604	EPSD	ICGC;COSMIC	7.604	Down-regulation
AGC_PKC_PKCd_PRKCD_ST	O15350	TP73	Q05655	PRKCD	S333	K331N	331	Missense	proximal	-2	no	7.670	2.940	EPSD	ICGC	7.604	Loss
AGC_PKC_PKCd_PRKCD_ST	O15350	TP73	Q05655	PRKCD	S333	A336S	336	Missense	distal	3	no	7.670	7.735	EPSD	ICGC;COSMIC	7.604	Up-regulation
AGC_PKC_PKCd_PRKCD_ST	P12931	SRC	Q05655	PRKCD	S12	K7N	7	Missense	distal	-5	no	14.804	14.425	PhosphoSitePlus	ICGC	7.604	Down-regulation
AGC_PKC_PKCd_PRKCD_ST	P12931	SRC	Q05655	PRKCD	S12	R14L	14	Missense	proximal	2	no	14.804	7.926	PhosphoSitePlus	ICGC;COSMIC	7.604	Down-regulation
AGC_PKC_PKCd_PRKCD_ST	P12931	SRC	Q05655	PRKCD	S12	Q13K	13	Missense	proximal	1	no	14.804	14.952	PhosphoSitePlus	ICGC;COSMIC	7.604	Up-regulation
AGC_PKC_PKCd_PRKCD_ST	P12931	SRC	Q05655	PRKCD	S17	R14L	14	Missense	distal	-3	no	14.401	9.214	EPSD	ICGC;COSMIC	7.604	Down-regulation
AGC_PKC_PKCd_PRKCD_ST	P12931	SRC	Q05655	PRKCD	S17	Q13K	13	Missense	distal	-4	no	14.401	14.060	EPSD	ICGC;COSMIC	7.604	Down-regulation
AGC_PKC_PKCd_PRKCD_ST	P12931	SRC	Q05655	PRKCD	S51	A52T	52	Missense	proximal	1	no	8.706	8.768	EPSD	ICGC;COSMIC	7.604	Up-regulation
AGC_PKC_PKCd_PRKCD_ST	P12931	SRC	Q05655	PRKCD	S269	A262D	262	Missense	distal	-7	no	15.167	15.165	EPSD	ICGC;COSMIC	7.604	Down-regulation
AGC_PKC_PKCd_PRKCD_ST	P12931	SRC	Q05655	PRKCD	S269	P266T	266	Missense	distal	-3	no	15.167	14.318	EPSD	ICGC;COSMIC	7.604	Down-regulation
AGC_PKC_PKCd_PRKCD_ST	P12931	SRC	Q05655	PRKCD	S269	L276P	276	Missense	distal	7	no	15.167	15.197	EPSD	ICGC;COSMIC	7.604	Up-regulation
AGC_PKC_PKCd_PRKCD_ST	P52757	CHN2	Q05655	PRKCD	S167	R163T	163	Missense	distal	-4	no	11.819	12.103	EPSD	ICGC;COSMIC	7.604	Up-regulation
AGC_PKC_PKCd_PRKCD_ST	P52757	CHN2	Q05655	PRKCD	S167	R163L	163	Missense	distal	-4	no	11.819	12.212	EPSD	ICGC;COSMIC	7.604	Up-regulation
AGC_PKC_PKCd_PRKCD_ST	P52757	CHN2	Q05655	PRKCD	S167	E164D	164	Missense	distal	-3	no	11.819	12.200	EPSD	ICGC;COSMIC	7.604	Up-regulation
AGC_PKC_PKCd_PRKCD_ST	P52757	CHN2	Q05655	PRKCD	S171	E164D	164	Missense	distal	-7	no	12.251	12.252	PhosphoSitePlus	ICGC;COSMIC	7.604	Up-regulation
AGC_PKC_PKCd_PRKCD_ST	P30086	PEBP1	Q05655	PRKCD	S52	S52R	52	Missense	central	0	yes	7.624	0.000	EPSD	ICGC;COSMIC	7.604	Loss
AGC_PKC_PKCd_PRKCD_ST	P30086	PEBP1	Q05655	PRKCD	S52	D56G	56	Missense	distal	4	no	7.624	7.585	EPSD	ICGC	7.604	Loss
AGC_PKC_PKCd_PRKCD_ST	P30086	PEBP1	Q05655	PRKCD	S52	N48D	48	Missense	distal	-4	no	7.624	7.599	EPSD	ICGC;COSMIC	7.604	Loss
AGC_PKC_PKCd_PRKCD_ST	P30086	PEBP1	Q05655	PRKCD	S54	S52R	52	Missense	proximal	-2	no	3.645	8.494	EPSD	ICGC;COSMIC	7.604	Gain
AGC_PKC_PKCd_PRKCD_ST	P30086	PEBP1	Q05655	PRKCD	S75	L68P	68	Missense	distal	-7	no	7.860	7.871	EPSD	ICGC;COSMIC	7.604	Up-regulation
AGC_PKC_PKCd_PRKCD_ST	P30086	PEBP1	Q05655	PRKCD	S75	R82I	82	Missense	distal	7	no	7.860	7.727	EPSD	ICGC;COSMIC	7.604	Down-regulation
AGC_PKC_PKCd_PRKCD_ST	P30086	PEBP1	Q05655	PRKCD	S75	S75I	75	Missense	central	0	yes	7.860	0.000	EPSD	ICGC	7.604	Loss
AGC_PKC_PKCd_PRKCD_ST	P30086	PEBP1	Q05655	PRKCD	S75	D70Y	70	Missense	distal	-5	no	7.860	7.764	EPSD	ICGC;COSMIC	7.604	Down-regulation
AGC_PKC_PKCd_PRKCD_ST	P30086	PEBP1	Q05655	PRKCD	S139	P136L	136	Missense	distal	-3	no	8.671	7.728	EPSD	ICGC;COSMIC	7.604	Down-regulation
AGC_PKC_PKCd_PRKCD_ST	P30086	PEBP1	Q05655	PRKCD	S139	C133F	133	Missense	distal	-6	no	8.671	8.607	EPSD	ICGC	7.604	Down-regulation
AGC_PKC_PKCd_PRKCD_ST	P30086	PEBP1	Q05655	PRKCD	S139	H145Y	145	Missense	distal	6	no	8.671	8.647	EPSD	ICGC;COSMIC	7.604	Down-regulation
AGC_PKC_PKCd_PRKCD_ST	Q8IV61	RASGRP3	Q05655	PRKCD	T133	V138L	138	Missense	distal	5	no	19.126	19.193	PhosphoSitePlus	ICGC;COSMIC	7.604	Up-regulation
AGC_PKC_PKCd_PRKCD_ST	Q8IV61	RASGRP3	Q05655	PRKCD	T133	D127Y	127	Missense	distal	-6	no	19.126	19.240	PhosphoSitePlus	ICGC	7.604	Up-regulation
AGC_PKC_PKCd_PRKCD_ST	Q8IV61	RASGRP3	Q05655	PRKCD	T133	V138I	138	Missense	distal	5	no	19.126	19.050	PhosphoSitePlus	ICGC	7.604	Down-regulation
AGC_PKC_PKCd_PRKCD_ST	Q8IV61	RASGRP3	Q05655	PRKCD	S385	R383I	383	Missense	proximal	-2	no	8.525	1.800	EPSD	ICGC	7.604	Loss
AGC_PKC_PKCd_PRKCD_ST	Q8IV61	RASGRP3	Q05655	PRKCD	S385	T390S	390	Missense	distal	5	no	8.525	8.621	EPSD	ICGC;COSMIC	7.604	Up-regulation
AGC_PKC_PKCd_PRKCD_ST	Q8IV61	RASGRP3	Q05655	PRKCD	S552	R545M	545	Missense	distal	-7	no	8.325	8.301	EPSD	ICGC;COSMIC	7.604	Down-regulation
AGC_PKC_PKCd_PRKCD_ST	Q8IV61	RASGRP3	Q05655	PRKCD	S552	A550V	550	Missense	proximal	-2	no	8.325	7.694	EPSD	ICGC;COSMIC;GDSC;CCLE	7.604	Down-regulation
AGC_PKC_PKCd_PRKCD_ST	Q8IV61	RASGRP3	Q05655	PRKCD	S552	R549Q	549	Missense	distal	-3	no	8.325	3.167	EPSD	ICGC;COSMIC	7.604	Loss
AGC_PKC_PKCd_PRKCD_ST	Q8IV61	RASGRP3	Q05655	PRKCD	S597	I591T	591	Missense	distal	-6	no	9.497	9.269	EPSD	ICGC;COSMIC	7.604	Down-regulation
AGC_PKC_PKCd_PRKCD_ST	Q8IV61	RASGRP3	Q05655	PRKCD	S597	S598Y	598	Missense	proximal	1	no	9.497	9.381	EPSD	ICGC;COSMIC	7.604	Down-regulation
AGC_PKC_PKCd_PRKCD_ST	Q8IV61	RASGRP3	Q05655	PRKCD	S597	S598F	598	Missense	proximal	1	no	9.497	9.448	EPSD	ICGC;CCLE	7.604	Down-regulation
AGC_PKC_PKCd_PRKCD_ST	Q8IV61	RASGRP3	Q05655	PRKCD	S598	I591T	591	Missense	distal	-7	no	7.876	7.886	EPSD	ICGC;COSMIC	7.604	Up-regulation
AGC_PKC_PKCd_PRKCD_ST	Q8IV61	RASGRP3	Q05655	PRKCD	S598	S598Y	598	Missense	central	0	yes	7.876	0.000	EPSD	ICGC;COSMIC	7.604	Loss
AGC_PKC_PKCd_PRKCD_ST	Q8IV61	RASGRP3	Q05655	PRKCD	S598	S598F	598	Missense	central	0	yes	7.876	0.000	EPSD	ICGC;CCLE	7.604	Loss
CAMK_PIM_PIM2_ST	P14618	PKM	Q9P1W9	PIM2	S37	D34E	34	Missense	distal	-3	no	4.471	5.243	EPSD	ICGC	4.322	Up-regulation
CAMK_PIM_PIM2_ST	P14618	PKM	Q9P1W9	PIM2	S37	P38T	38	Missense	proximal	1	no	4.471	4.665	EPSD	ICGC	4.322	Up-regulation
CAMK_PIM_PIM2_ST	P14618	PKM	Q9P1W9	PIM2	S127	G128D	128	Missense	proximal	1	no	5.576	5.812	EPSD	ICGC;COSMIC	4.322	Up-regulation
CAMK_PIM_PIM2_ST	P38936	CDKN1A	Q9P1W9	PIM2	S31	S31R	31	Missense	central	0	yes	4.430	0.000	EPSD	ICGC;COSMIC	4.322	Loss
CAMK_PIM_PIM2_ST	P38936	CDKN1A	Q9P1W9	PIM2	S31	R32L	32	Missense	proximal	1	no	4.430	4.835	EPSD	ICGC	4.322	Up-regulation
CAMK_PIM_PIM2_ST	P38936	CDKN1A	Q9P1W9	PIM2	S31	E28K	28	Missense	distal	-3	no	4.430	4.745	EPSD	ICGC;COSMIC	4.322	Up-regulation
CAMK_PIM_PIM2_ST	P38936	CDKN1A	Q9P1W9	PIM2	T145	R143L	143	Missense	proximal	-2	no	11.610	10.912	PhosphoSitePlus;EPSD	ICGC	4.322	Down-regulation
CAMK_PIM_PIM2_ST	P38936	CDKN1A	Q9P1W9	PIM2	T145	R142Q	142	Missense	distal	-3	no	11.610	9.965	PhosphoSitePlus;EPSD	ICGC	4.322	Down-regulation
CAMK_PIM_PIM2_ST	P38936	CDKN1A	Q9P1W9	PIM2	T145	R140Q	140	Missense	distal	-5	no	11.610	8.387	PhosphoSitePlus;EPSD	ICGC;COSMIC	4.322	Down-regulation
CAMK_PIM_PIM2_ST	P38936	CDKN1A	Q9P1W9	PIM2	S146	R143L	143	Missense	distal	-3	no	9.959	8.933	EPSD;PhosphoSitePlus	ICGC	4.322	Down-regulation
CAMK_PIM_PIM2_ST	P38936	CDKN1A	Q9P1W9	PIM2	S146	R142Q	142	Missense	distal	-4	no	9.959	9.977	EPSD;PhosphoSitePlus	ICGC	4.322	Up-regulation
CAMK_PIM_PIM2_ST	P38936	CDKN1A	Q9P1W9	PIM2	S146	R140Q	140	Missense	distal	-6	no	9.959	9.033	EPSD;PhosphoSitePlus	ICGC;COSMIC	4.322	Down-regulation
CAMK_PIM_PIM2_ST	P35568	IRS1	Q9P1W9	PIM2	S189	R184H	184	Missense	distal	-5	no	4.580	2.133	EPSD	ICGC	4.322	Loss
CAMK_PIM_PIM2_ST	P35568	IRS1	Q9P1W9	PIM2	S270	R265H	265	Missense	distal	-5	no	5.498	3.051	EPSD	ICGC	4.322	Loss
CAMK_PIM_PIM2_ST	P35568	IRS1	Q9P1W9	PIM2	S270	F264L	264	Missense	distal	-6	no	5.498	5.741	EPSD	ICGC	4.322	Up-regulation
CAMK_PIM_PIM2_ST	P35568	IRS1	Q9P1W9	PIM2	S270	S272P	272	Missense	proximal	2	no	5.498	5.431	EPSD	ICGC	4.322	Down-regulation
CAMK_PIM_PIM2_ST	P35568	IRS1	Q9P1W9	PIM2	S270	S268I	268	Missense	proximal	-2	no	5.498	5.522	EPSD	ICGC;COSMIC	4.322	Up-regulation
CAMK_PIM_PIM2_ST	P35568	IRS1	Q9P1W9	PIM2	S272	R265H	265	Missense	distal	-7	no	5.034	4.708	EPSD	ICGC	4.322	Down-regulation
CAMK_PIM_PIM2_ST	P35568	IRS1	Q9P1W9	PIM2	S272	S272P	272	Missense	central	0	yes	5.034	0.000	EPSD	ICGC	4.322	Loss
CAMK_PIM_PIM2_ST	P35568	IRS1	Q9P1W9	PIM2	S272	N278T	278	Missense	distal	6	no	5.034	5.042	EPSD	ICGC	4.322	Up-regulation
CAMK_PIM_PIM2_ST	P35568	IRS1	Q9P1W9	PIM2	S272	S268I	268	Missense	distal	-4	no	5.034	5.087	EPSD	ICGC;COSMIC	4.322	Up-regulation
CAMK_PIM_PIM2_ST	P35568	IRS1	Q9P1W9	PIM2	S307	T300P	300	Missense	distal	-7	no	5.185	5.532	EPSD	ICGC;COSMIC;GDSC	4.322	Up-regulation
CAMK_PIM_PIM2_ST	P35568	IRS1	Q9P1W9	PIM2	S312	G319R	319	Missense	distal	7	no	5.068	4.921	EPSD	ICGC;COSMIC	4.322	Down-regulation
CAMK_PIM_PIM2_ST	P35568	IRS1	Q9P1W9	PIM2	S396	S402C	402	Missense	distal	6	no	4.297	4.467	EPSD	ICGC;COSMIC	4.322	Gain
CAMK_PIM_PIM2_ST	P35568	IRS1	Q9P1W9	PIM2	S396	S393T	393	Missense	distal	-3	no	4.297	5.107	EPSD	ICGC;COSMIC	4.322	Gain
CAMK_PIM_PIM2_ST	P35568	IRS1	Q9P1W9	PIM2	S415	S412P	412	Missense	distal	-3	no	5.097	5.782	EPSD	ICGC	4.322	Up-regulation
CAMK_PIM_PIM2_ST	P35568	IRS1	Q9P1W9	PIM2	S415	S421R	421	Missense	distal	6	no	5.097	4.957	EPSD	ICGC	4.322	Down-regulation
CAMK_PIM_PIM2_ST	P35568	IRS1	Q9P1W9	PIM2	S415	A414D	414	Missense	proximal	-1	no	5.097	5.417	EPSD	ICGC	4.322	Up-regulation
CAMK_PIM_PIM2_ST	P35568	IRS1	Q9P1W9	PIM2	S415	R411L	411	Missense	distal	-4	no	5.097	5.162	EPSD	ICGC;COSMIC	4.322	Up-regulation
CAMK_PIM_PIM2_ST	P35568	IRS1	Q9P1W9	PIM2	S415	R410W	410	Missense	distal	-5	no	5.097	1.651	EPSD	ICGC	4.322	Loss
CAMK_PIM_PIM2_ST	P35568	IRS1	Q9P1W9	PIM2	S527	S531Y	531	Missense	distal	4	no	4.512	5.015	EPSD	ICGC	4.322	Up-regulation
CAMK_PIM_PIM2_ST	P35568	IRS1	Q9P1W9	PIM2	T533	P540S	540	Missense	distal	7	no	4.687	4.849	EPSD	ICGC	4.322	Up-regulation
CAMK_PIM_PIM2_ST	P35568	IRS1	Q9P1W9	PIM2	T533	S531Y	531	Missense	proximal	-2	no	4.687	4.601	EPSD	ICGC	4.322	Down-regulation
CAMK_PIM_PIM2_ST	P35568	IRS1	Q9P1W9	PIM2	S641	P634S	634	Missense	distal	-7	no	4.990	4.719	EPSD	ICGC;COSMIC	4.322	Down-regulation
CAMK_PIM_PIM2_ST	P35568	IRS1	Q9P1W9	PIM2	T859	P866T	866	Missense	distal	7	no	5.482	5.648	EPSD	ICGC	4.322	Up-regulation
CAMK_PIM_PIM2_ST	P35568	IRS1	Q9P1W9	PIM2	S918	R922G	922	Missense	distal	4	no	4.143	4.610	EPSD	ICGC;COSMIC	4.322	Gain
CAMK_PIM_PIM2_ST	P35568	IRS1	Q9P1W9	PIM2	T938	E939D	939	Missense	proximal	1	no	4.540	4.550	EPSD	ICGC	4.322	Up-regulation
CAMK_PIM_PIM2_ST	P35568	IRS1	Q9P1W9	PIM2	S1101	S1106L	1106	Missense	distal	5	no	12.128	12.064	PhosphoSitePlus	ICGC;COSMIC	4.322	Down-regulation
CAMK_PIM_PIM2_ST	P35568	IRS1	Q9P1W9	PIM2	S1142	D1137N	1137	Missense	distal	-5	no	4.575	5.115	EPSD	ICGC	4.322	Up-regulation
CAMK_CAMK2_CAMK2A_ST	P24588	AKAP5	Q9UQM7	CAMK2A	S53	A46S	46	Missense	distal	-7	no	6.822	7.060	EPSD	ICGC	4.810	Up-regulation
CAMK_CAMK2_CAMK2A_ST	P24588	AKAP5	Q9UQM7	CAMK2A	S53	S53Y	53	Missense	central	0	yes	6.822	0.000	EPSD	ICGC;COSMIC	4.810	Loss
CAMK_CAMK2_CAMK2A_ST	P24588	AKAP5	Q9UQM7	CAMK2A	S92	Q98H	98	Missense	distal	6	no	7.739	7.707	PhosphoSitePlus;EPSD	ICGC;COSMIC	4.810	Down-regulation
CAMK_CAMK2_CAMK2A_ST	P24588	AKAP5	Q9UQM7	CAMK2A	S178	Q180H	180	Missense	proximal	2	no	5.209	4.772	EPSD	ICGC	4.810	Loss
CAMK_CAMK2_CAMK2A_ST	P24588	AKAP5	Q9UQM7	CAMK2A	S178	G185V	185	Missense	distal	7	no	5.209	5.190	EPSD	ICGC	4.810	Down-regulation
CAMK_CAMK2_CAMK2A_ST	Q14524	SCN5A	Q9UQM7	CAMK2A	S11	T10N	10	Missense	proximal	-1	no	7.285	7.310	EPSD;PhosphoSitePlus	ICGC;COSMIC	4.810	Up-regulation
CAMK_CAMK2_CAMK2A_ST	Q14524	SCN5A	Q9UQM7	CAMK2A	S11	G9V	9	Missense	proximal	-2	no	7.285	7.133	EPSD;PhosphoSitePlus	ICGC;COSMIC	4.810	Down-regulation
CAMK_CAMK2_CAMK2A_ST	Q14524	SCN5A	Q9UQM7	CAMK2A	S11	R18W	18	Missense	distal	7	no	7.285	7.600	EPSD;PhosphoSitePlus	ICGC;COSMIC	4.810	Up-regulation
CAMK_CAMK2_CAMK2A_ST	Q14524	SCN5A	Q9UQM7	CAMK2A	S12	T10N	10	Missense	proximal	-2	no	5.341	5.533	EPSD;PhosphoSitePlus	ICGC;COSMIC	4.810	Up-regulation
CAMK_CAMK2_CAMK2A_ST	Q14524	SCN5A	Q9UQM7	CAMK2A	S12	G9V	9	Missense	distal	-3	no	5.341	4.817	EPSD;PhosphoSitePlus	ICGC;COSMIC	4.810	Down-regulation
CAMK_CAMK2_CAMK2A_ST	Q14524	SCN5A	Q9UQM7	CAMK2A	S12	R18W	18	Missense	distal	6	no	5.341	5.102	EPSD;PhosphoSitePlus	ICGC;COSMIC	4.810	Down-regulation
CAMK_CAMK2_CAMK2A_ST	Q14524	SCN5A	Q9UQM7	CAMK2A	T17	T10N	10	Missense	distal	-7	no	8.351	8.345	EPSD;PhosphoSitePlus	ICGC;COSMIC	4.810	Down-regulation
CAMK_CAMK2_CAMK2A_ST	Q14524	SCN5A	Q9UQM7	CAMK2A	T17	R18W	18	Missense	proximal	1	no	8.351	8.061	EPSD;PhosphoSitePlus	ICGC;COSMIC	4.810	Down-regulation
CAMK_CAMK2_CAMK2A_ST	Q14524	SCN5A	Q9UQM7	CAMK2A	T37	K31Q	31	Missense	distal	-6	no	5.348	5.323	EPSD	ICGC;COSMIC	4.810	Down-regulation
CAMK_CAMK2_CAMK2A_ST	Q14524	SCN5A	Q9UQM7	CAMK2A	T37	E30K	30	Missense	distal	-7	no	5.348	5.239	EPSD	ICGC;COSMIC	4.810	Down-regulation
CAMK_CAMK2_CAMK2A_ST	Q14524	SCN5A	Q9UQM7	CAMK2A	S42	E49K	49	Missense	distal	7	no	4.625	4.836	EPSD;PhosphoSitePlus	ICGC	4.810	Gain
CAMK_CAMK2_CAMK2A_ST	Q14524	SCN5A	Q9UQM7	CAMK2A	S483	G490E	490	Missense	distal	7	no	5.243	5.005	EPSD;PhosphoSitePlus	ICGC	4.810	Down-regulation
CAMK_CAMK2_CAMK2A_ST	Q14524	SCN5A	Q9UQM7	CAMK2A	S483	R481W	481	Missense	proximal	-2	no	5.243	4.424	EPSD;PhosphoSitePlus	ICGC;COSMIC	4.810	Loss
CAMK_CAMK2_CAMK2A_ST	Q14524	SCN5A	Q9UQM7	CAMK2A	S483	S484P	484	Missense	proximal	1	no	5.243	4.875	EPSD;PhosphoSitePlus	ICGC	4.810	Down-regulation
CAMK_CAMK2_CAMK2A_ST	Q14524	SCN5A	Q9UQM7	CAMK2A	S483	R481L	481	Missense	proximal	-2	no	5.243	5.069	EPSD;PhosphoSitePlus	ICGC;COSMIC	4.810	Down-regulation
CAMK_CAMK2_CAMK2A_ST	Q14524	SCN5A	Q9UQM7	CAMK2A	S483	G490V	490	Missense	distal	7	no	5.243	5.223	EPSD;PhosphoSitePlus	ICGC;COSMIC	4.810	Down-regulation
CAMK_CAMK2_CAMK2A_ST	Q14524	SCN5A	Q9UQM7	CAMK2A	S484	G490E	490	Missense	distal	6	no	7.239	7.318	EPSD;PhosphoSitePlus	ICGC	4.810	Up-regulation
CAMK_CAMK2_CAMK2A_ST	Q14524	SCN5A	Q9UQM7	CAMK2A	S484	R481W	481	Missense	distal	-3	no	7.239	-4.781	EPSD;PhosphoSitePlus	ICGC;COSMIC	4.810	Loss
CAMK_CAMK2_CAMK2A_ST	Q14524	SCN5A	Q9UQM7	CAMK2A	S484	S484P	484	Missense	central	0	yes	7.239	0.000	EPSD;PhosphoSitePlus	ICGC	4.810	Loss
CAMK_CAMK2_CAMK2A_ST	Q14524	SCN5A	Q9UQM7	CAMK2A	S484	R481L	481	Missense	distal	-3	no	7.239	2.116	EPSD;PhosphoSitePlus	ICGC;COSMIC	4.810	Loss
CAMK_CAMK2_CAMK2A_ST	Q14524	SCN5A	Q9UQM7	CAMK2A	S484	G490V	490	Missense	distal	6	no	7.239	7.177	EPSD;PhosphoSitePlus	ICGC;COSMIC	4.810	Down-regulation
CAMK_CAMK2_CAMK2A_ST	Q14524	SCN5A	Q9UQM7	CAMK2A	S499	K496R	496	Missense	distal	-3	no	6.630	8.898	EPSD;PhosphoSitePlus	ICGC	4.810	Up-regulation
CAMK_CAMK2_CAMK2A_ST	Q14524	SCN5A	Q9UQM7	CAMK2A	S499	P503L	503	Missense	distal	4	no	6.630	6.593	EPSD;PhosphoSitePlus	ICGC	4.810	Down-regulation
CAMK_CAMK2_CAMK2A_ST	Q14524	SCN5A	Q9UQM7	CAMK2A	S499	S497F	497	Missense	proximal	-2	no	6.630	5.845	EPSD;PhosphoSitePlus	ICGC	4.810	Down-regulation
CAMK_CAMK2_CAMK2A_ST	Q14524	SCN5A	Q9UQM7	CAMK2A	S499	P495H	495	Missense	distal	-4	no	6.630	6.816	EPSD;PhosphoSitePlus	ICGC;COSMIC	4.810	Up-regulation
CAMK_CAMK2_CAMK2A_ST	Q14524	SCN5A	Q9UQM7	CAMK2A	S516	S510N	510	Missense	distal	-6	no	7.724	7.825	EPSD;PhosphoSitePlus	ICGC	4.810	Up-regulation
CAMK_CAMK2_CAMK2A_ST	Q14524	SCN5A	Q9UQM7	CAMK2A	S516	S510G	510	Missense	distal	-6	no	7.724	7.816	EPSD;PhosphoSitePlus	ICGC;COSMIC	4.810	Up-regulation
CAMK_CAMK2_CAMK2A_ST	Q14524	SCN5A	Q9UQM7	CAMK2A	S524	R526H	526	Missense	proximal	2	no	5.646	4.578	EPSD	ICGC;COSMIC	4.810	Loss
CAMK_CAMK2_CAMK2A_ST	Q14524	SCN5A	Q9UQM7	CAMK2A	S524	G527R	527	Missense	distal	3	no	5.646	5.702	EPSD	ICGC;COSMIC	4.810	Up-regulation
CAMK_CAMK2_CAMK2A_ST	Q14524	SCN5A	Q9UQM7	CAMK2A	S581	A582V	582	Missense	proximal	1	no	4.885	5.237	EPSD	ICGC;COSMIC	4.810	Up-regulation
CAMK_CAMK2_CAMK2A_ST	Q14524	SCN5A	Q9UQM7	CAMK2A	S581	H585N	585	Missense	distal	4	no	4.885	4.865	EPSD	ICGC	4.810	Down-regulation
CAMK_CAMK2_CAMK2A_ST	Q14524	SCN5A	Q9UQM7	CAMK2A	S581	A586D	586	Missense	distal	5	no	4.885	4.710	EPSD	ICGC;COSMIC	4.810	Loss
CAMK_CAMK2_CAMK2A_ST	Q14524	SCN5A	Q9UQM7	CAMK2A	T594	G599E	599	Missense	distal	5	no	7.816	7.938	EPSD	ICGC	4.810	Up-regulation
CAMK_CAMK2_CAMK2A_ST	Q14524	SCN5A	Q9UQM7	CAMK2A	S664	V668I	668	Missense	distal	4	no	7.191	7.034	EPSD;PhosphoSitePlus	ICGC;COSMIC	4.810	Down-regulation
CAMK_CAMK2_CAMK2A_ST	Q14524	SCN5A	Q9UQM7	CAMK2A	S664	R661W	661	Missense	distal	-3	no	7.191	-4.830	EPSD;PhosphoSitePlus	ICGC;COSMIC	4.810	Loss
CAMK_CAMK2_CAMK2A_ST	Q14524	SCN5A	Q9UQM7	CAMK2A	S664	S664R	664	Missense	central	0	yes	7.191	0.000	EPSD;PhosphoSitePlus	ICGC	4.810	Loss
CAMK_CAMK2_CAMK2A_ST	Q14524	SCN5A	Q9UQM7	CAMK2A	S667	V668I	668	Missense	proximal	1	no	4.697	4.905	EPSD;PhosphoSitePlus	ICGC;COSMIC	4.810	Gain
CAMK_CAMK2_CAMK2A_ST	Q14524	SCN5A	Q9UQM7	CAMK2A	S667	R661W	661	Missense	distal	-6	no	4.697	4.975	EPSD;PhosphoSitePlus	ICGC;COSMIC	4.810	Gain
CAMK_CAMK2_CAMK2A_ST	Q14524	SCN5A	Q9UQM7	CAMK2A	S667	S664R	664	Missense	distal	-3	no	4.697	9.157	EPSD;PhosphoSitePlus	ICGC	4.810	Gain
CAMK_CAMK2_CAMK2A_ST	Q14524	SCN5A	Q9UQM7	CAMK2A	S1985	D1978N	1978	Missense	distal	-7	no	8.465	8.350	EPSD	ICGC;COSMIC	4.810	Down-regulation
CAMK_CAMK2_CAMK2A_ST	P35367	HRH1	Q9UQM7	CAMK2A	T142	S145L	145	Missense	distal	3	no	6.650	6.338	PhosphoSitePlus;EPSD	ICGC;COSMIC;GDSC;CCLE	4.810	Down-regulation
CAMK_CAMK2_CAMK2A_ST	P35367	HRH1	Q9UQM7	CAMK2A	S277	Q278K	278	Missense	proximal	1	no	5.238	5.282	EPSD	ICGC	4.810	Up-regulation
CAMK_CAMK2_CAMK2A_ST	P35367	HRH1	Q9UQM7	CAMK2A	S363	T365I	365	Missense	proximal	2	no	6.631	7.188	EPSD	ICGC;COSMIC	4.810	Up-regulation
CAMK_CAMK2_CAMK2A_ST	P35367	HRH1	Q9UQM7	CAMK2A	S363	A370T	370	Missense	distal	7	no	6.631	6.680	EPSD	ICGC;GDSC;CCLE	4.810	Up-regulation
CAMK_CAMK2_CAMK2A_ST	P35367	HRH1	Q9UQM7	CAMK2A	S396	S396W	396	Missense	central	0	yes	7.356	0.000	EPSD;PhosphoSitePlus	ICGC;COSMIC	4.810	Loss
CAMK_CAMK2_CAMK2A_ST	P35367	HRH1	Q9UQM7	CAMK2A	S396	R393S	393	Missense	distal	-3	no	7.356	2.895	EPSD;PhosphoSitePlus	ICGC;COSMIC	4.810	Loss
CAMK_CAMK2_CAMK2A_ST	P35367	HRH1	Q9UQM7	CAMK2A	S398	S396W	396	Missense	proximal	-2	no	9.364	8.617	EPSD;PhosphoSitePlus	ICGC;COSMIC	4.810	Down-regulation
CAMK_CAMK2_CAMK2A_ST	P35367	HRH1	Q9UQM7	CAMK2A	S398	R393S	393	Missense	distal	-5	no	9.364	9.435	EPSD;PhosphoSitePlus	ICGC;COSMIC	4.810	Up-regulation
CAMK_CAMK2_CAMK2A_ST	P15036	ETS2	Q9UQM7	CAMK2A	S246	C252S	252	Missense	distal	6	no	8.446	8.609	EPSD;PhosphoSitePlus	ICGC	4.810	Up-regulation
CAMK_CAMK2_CAMK2A_ST	P15036	ETS2	Q9UQM7	CAMK2A	S246	P240T	240	Missense	distal	-6	no	8.446	8.466	EPSD;PhosphoSitePlus	ICGC;COSMIC	4.810	Up-regulation
CAMK_CAMK2_CAMK2A_ST	P15036	ETS2	Q9UQM7	CAMK2A	S246	K241R	241	Missense	distal	-5	no	8.446	8.490	EPSD;PhosphoSitePlus	ICGC;COSMIC	4.810	Up-regulation
CAMK_CAMK2_CAMK2A_ST	P15036	ETS2	Q9UQM7	CAMK2A	S310	R307Q	307	Missense	distal	-3	no	6.673	3.102	PhosphoSitePlus;EPSD	ICGC;COSMIC	4.810	Loss
CAMK_CAMK2_CAMK2A_ST	P15036	ETS2	Q9UQM7	CAMK2A	S310	P309H	309	Missense	proximal	-1	no	6.673	6.917	PhosphoSitePlus;EPSD	ICGC;COSMIC	4.810	Up-regulation
CAMK_CAMK2_CAMK2A_ST	P15036	ETS2	Q9UQM7	CAMK2A	S313	C318R	318	Missense	distal	5	no	4.578	4.870	EPSD;PhosphoSitePlus	ICGC	4.810	Gain
CAMK_CAMK2_CAMK2A_ST	P15036	ETS2	Q9UQM7	CAMK2A	S321	C318R	318	Missense	distal	-3	no	2.481	8.062	EPSD	ICGC	4.810	Gain
CAMK_CAMK2_CAMK2A_ST	P23677	ITPKA	Q9UQM7	CAMK2A	S20	G14E	14	Missense	distal	-6	no	8.002	7.792	EPSD	ICGC	4.810	Down-regulation
CAMK_CAMK2_CAMK2A_ST	P23677	ITPKA	Q9UQM7	CAMK2A	S121	R118H	118	Missense	distal	-3	no	7.069	1.572	EPSD	ICGC;COSMIC	4.810	Loss
CAMK_CAMK2_CAMK2A_ST	P23677	ITPKA	Q9UQM7	CAMK2A	S121	V125A	125	Missense	distal	4	no	7.069	7.123	EPSD	ICGC;COSMIC	4.810	Up-regulation
CAMK_CAMK2_CAMK2A_ST	P23677	ITPKA	Q9UQM7	CAMK2A	T122	R118H	118	Missense	distal	-4	no	8.134	8.010	EPSD	ICGC;COSMIC	4.810	Down-regulation
CAMK_CAMK2_CAMK2A_ST	P23677	ITPKA	Q9UQM7	CAMK2A	T122	V125A	125	Missense	distal	3	no	8.134	8.196	EPSD	ICGC;COSMIC	4.810	Up-regulation
CAMK_CAMK2_CAMK2A_ST	P23677	ITPKA	Q9UQM7	CAMK2A	T311	A306V	306	Missense	distal	-5	no	6.144	6.022	PhosphoSitePlus	ICGC;COSMIC	4.810	Down-regulation
CAMK_CAMK2_CAMK2A_ST	Q9Y618	NCOR2	Q9UQM7	CAMK2A	S67	P74L	74	Missense	distal	7	no	6.753	6.818	EPSD	ICGC;COSMIC	4.810	Up-regulation
CAMK_CAMK2_CAMK2A_ST	Q9Y618	NCOR2	Q9UQM7	CAMK2A	S67	Q60K	60	Missense	distal	-7	no	6.753	6.630	EPSD	ICGC	4.810	Down-regulation
CAMK_CAMK2_CAMK2A_ST	Q9Y618	NCOR2	Q9UQM7	CAMK2A	S67	P74T	74	Missense	distal	7	no	6.753	6.749	EPSD	ICGC	4.810	Down-regulation
CAMK_CAMK2_CAMK2A_ST	Q9Y618	NCOR2	Q9UQM7	CAMK2A	S88	P93L	93	Missense	distal	5	no	6.621	6.562	EPSD	ICGC;COSMIC	4.810	Down-regulation
CAMK_CAMK2_CAMK2A_ST	Q9Y618	NCOR2	Q9UQM7	CAMK2A	S88	H83Q	83	Missense	distal	-5	no	6.621	6.578	EPSD	ICGC	4.810	Down-regulation
CAMK_CAMK2_CAMK2A_ST	Q9Y618	NCOR2	Q9UQM7	CAMK2A	S132	R139H	139	Missense	distal	7	no	4.822	4.773	EPSD	ICGC;COSMIC;GDSC;CCLE	4.810	Loss
CAMK_CAMK2_CAMK2A_ST	Q9Y618	NCOR2	Q9UQM7	CAMK2A	S132	P129H	129	Missense	distal	-3	no	4.822	4.242	EPSD	ICGC	4.810	Loss
CAMK_CAMK2_CAMK2A_ST	Q9Y618	NCOR2	Q9UQM7	CAMK2A	S132	T136N	136	Missense	distal	4	no	4.822	4.834	EPSD	ICGC	4.810	Up-regulation
CAMK_CAMK2_CAMK2A_ST	Q9Y618	NCOR2	Q9UQM7	CAMK2A	S140	R139H	139	Missense	proximal	-1	no	5.987	6.132	EPSD	ICGC;COSMIC;GDSC;CCLE	4.810	Up-regulation
CAMK_CAMK2_CAMK2A_ST	Q9Y618	NCOR2	Q9UQM7	CAMK2A	S140	T136N	136	Missense	distal	-4	no	5.987	6.106	EPSD	ICGC	4.810	Up-regulation
CAMK_CAMK2_CAMK2A_ST	Q9Y618	NCOR2	Q9UQM7	CAMK2A	S225	D232N	232	Missense	distal	7	no	5.925	5.907	EPSD	ICGC;COSMIC	4.810	Down-regulation
CAMK_CAMK2_CAMK2A_ST	Q9Y618	NCOR2	Q9UQM7	CAMK2A	S225	D232Y	232	Missense	distal	7	no	5.925	6.034	EPSD	ICGC;COSMIC	4.810	Up-regulation
CAMK_CAMK2_CAMK2A_ST	Q9Y618	NCOR2	Q9UQM7	CAMK2A	S516	E518D	518	Missense	proximal	2	no	4.339	5.255	EPSD	ICGC	4.810	Gain
CAMK_CAMK2_CAMK2A_ST	Q9Y618	NCOR2	Q9UQM7	CAMK2A	S939	P942L	942	Missense	distal	3	no	7.929	7.889	EPSD	ICGC;COSMIC	4.810	Down-regulation
CAMK_CAMK2_CAMK2A_ST	Q9Y618	NCOR2	Q9UQM7	CAMK2A	S939	L945Q	945	Missense	distal	6	no	7.929	8.052	EPSD	ICGC	4.810	Up-regulation
CAMK_CAMK2_CAMK2A_ST	Q9Y618	NCOR2	Q9UQM7	CAMK2A	S1023	S1025P	1025	Missense	proximal	2	no	7.889	7.412	EPSD	ICGC	4.810	Down-regulation
CAMK_CAMK2_CAMK2A_ST	Q9Y618	NCOR2	Q9UQM7	CAMK2A	S1025	S1025P	1025	Missense	central	0	yes	5.954	0.000	EPSD	ICGC	4.810	Loss
CAMK_CAMK2_CAMK2A_ST	Q9Y618	NCOR2	Q9UQM7	CAMK2A	S1627	L1622P	1622	Missense	distal	-5	no	5.850	5.943	EPSD	ICGC	4.810	Up-regulation
CAMK_CAMK2_CAMK2A_ST	Q9Y618	NCOR2	Q9UQM7	CAMK2A	S1722	R1719Q	1719	Missense	distal	-3	no	8.971	5.400	EPSD	ICGC	4.810	Down-regulation
CAMK_CAMK2_CAMK2A_ST	Q9Y618	NCOR2	Q9UQM7	CAMK2A	S1782	S1782F	1782	Missense	central	0	yes	7.652	0.000	EPSD	ICGC;COSMIC	4.810	Loss
CAMK_CAMK2_CAMK2A_ST	Q9Y618	NCOR2	Q9UQM7	CAMK2A	S1861	H1866R	1866	Missense	distal	5	no	8.372	8.258	EPSD	ICGC;COSMIC	4.810	Down-regulation
CAMK_CAMK2_CAMK2A_ST	Q9Y618	NCOR2	Q9UQM7	CAMK2A	S1869	H1866R	1866	Missense	distal	-3	no	3.342	8.839	EPSD	ICGC;COSMIC	4.810	Gain
CAMK_CAMK2_CAMK2A_ST	Q14654	KCNJ11	Q9UQM7	CAMK2A	T180	R176H	176	Missense	distal	-4	no	7.115	6.991	PhosphoSitePlus;EPSD	ICGC;COSMIC;GDSC;CCLE	4.810	Down-regulation
CAMK_CAMK2_CAMK2A_ST	Q14654	KCNJ11	Q9UQM7	CAMK2A	T224	E229K	229	Missense	distal	5	no	5.257	5.287	EPSD;PhosphoSitePlus	ICGC	4.810	Up-regulation
CAMK_CAMK2_CAMK2A_ST	Q14654	KCNJ11	Q9UQM7	CAMK2A	T224	E227K	227	Missense	distal	3	no	5.257	5.092	EPSD;PhosphoSitePlus	ICGC;COSMIC	4.810	Down-regulation
CAMK_CAMK2_CAMK2A_ST	Q14654	KCNJ11	Q9UQM7	CAMK2A	T224	R221C	221	Missense	distal	-3	no	5.257	-0.324	EPSD;PhosphoSitePlus	ICGC;COSMIC	4.810	Loss
CAMK_CAMK2_CAMK2A_ST	Q14654	KCNJ11	Q9UQM7	CAMK2A	T224	R221H	221	Missense	distal	-3	no	5.257	-0.240	EPSD;PhosphoSitePlus	ICGC;COSMIC	4.810	Loss
CAMK_CAMK2_CAMK2A_ST	Q14654	KCNJ11	Q9UQM7	CAMK2A	T224	R221L	221	Missense	distal	-3	no	5.257	0.135	EPSD;PhosphoSitePlus	ICGC;COSMIC	4.810	Loss
CAMK_CAMK2_CAMK2A_ST	Q14654	KCNJ11	Q9UQM7	CAMK2A	T224	T223I	223	Missense	proximal	-1	no	5.257	5.244	EPSD;PhosphoSitePlus	ICGC;GDSC;CCLE	4.810	Down-regulation
CAMK_CAMK2_CAMK2A_ST	Q14654	KCNJ11	Q9UQM7	CAMK2A	T224	E227D	227	Missense	distal	3	no	5.257	5.134	EPSD;PhosphoSitePlus	ICGC;COSMIC	4.810	Down-regulation
CAMK_CAMK2_CAMK2A_ST	Q14654	KCNJ11	Q9UQM7	CAMK2A	S372	V373M	373	Missense	proximal	1	no	9.838	9.948	EPSD	ICGC;COSMIC;GDSC	4.810	Up-regulation
CAMK_CAMK2_CAMK2A_ST	Q14654	KCNJ11	Q9UQM7	CAMK2A	S372	R371H	371	Missense	proximal	-1	no	9.838	9.983	EPSD	ICGC	4.810	Up-regulation
CAMK_CAMK2_CAMK2A_ST	Q14654	KCNJ11	Q9UQM7	CAMK2A	S372	R369C	369	Missense	distal	-3	no	9.838	4.257	EPSD	ICGC;COSMIC	4.810	Loss
CAMK_CAMK2_CAMK2A_ST	Q96PH1	NOX5	Q9UQM7	CAMK2A	T540	T540A	540	Missense	central	0	yes	7.516	0.000	EPSD	ICGC	4.810	Loss
CAMK_CAMK2_CAMK2A_ST	Q96PH1	NOX5	Q9UQM7	CAMK2A	S544	T540A	540	Missense	distal	-4	no	4.550	4.840	EPSD	ICGC	4.810	Gain
CAMK_CAMK2_CAMK2A_ST	P05556	ITGB1	Q9UQM7	CAMK2A	S178	N171T	171	Missense	distal	-7	no	5.881	5.888	EPSD	ICGC;COSMIC	4.810	Up-regulation
CAMK_CAMK2_CAMK2A_ST	P05556	ITGB1	Q9UQM7	CAMK2A	S178	R175K	175	Missense	distal	-3	no	5.881	3.613	EPSD	ICGC	4.810	Loss
CAMK_CAMK2_CAMK2A_ST	P05556	ITGB1	Q9UQM7	CAMK2A	S593	T596S	596	Missense	distal	3	no	5.295	5.490	EPSD	ICGC;COSMIC	4.810	Up-regulation
CAMK_CAMK2_CAMK2A_ST	P05556	ITGB1	Q9UQM7	CAMK2A	S593	A589E	589	Missense	distal	-4	no	5.295	5.275	EPSD	ICGC	4.810	Down-regulation
CAMK_CAMK2_CAMK2A_ST	P05556	ITGB1	Q9UQM7	CAMK2A	S593	S593Y	593	Missense	central	0	yes	5.295	0.000	EPSD	ICGC	4.810	Loss
CAMK_CAMK2_CAMK2A_ST	P05556	ITGB1	Q9UQM7	CAMK2A	S593	T586I	586	Missense	distal	-7	no	5.295	5.365	EPSD	ICGC;COSMIC	4.810	Up-regulation
CAMK_CAMK2_CAMK2A_ST	P05556	ITGB1	Q9UQM7	CAMK2A	S593	D591A	591	Missense	proximal	-2	no	5.295	5.684	EPSD	ICGC	4.810	Up-regulation
CAMK_CAMK2_CAMK2A_ST	P05556	ITGB1	Q9UQM7	CAMK2A	S597	T596S	596	Missense	proximal	-1	no	4.862	5.023	EPSD	ICGC;COSMIC	4.810	Up-regulation
CAMK_CAMK2_CAMK2A_ST	P05556	ITGB1	Q9UQM7	CAMK2A	S597	N603K	603	Missense	distal	6	no	4.862	4.832	EPSD	ICGC	4.810	Down-regulation
CAMK_CAMK2_CAMK2A_ST	P05556	ITGB1	Q9UQM7	CAMK2A	S597	S593Y	593	Missense	distal	-4	no	4.862	4.538	EPSD	ICGC	4.810	Loss
CAMK_CAMK2_CAMK2A_ST	P05556	ITGB1	Q9UQM7	CAMK2A	S597	D591A	591	Missense	distal	-6	no	4.862	4.668	EPSD	ICGC	4.810	Loss
CAMK_CAMK2_CAMK2A_ST	P07101	TH	Q9UQM7	CAMK2A	S19	E20Q	20	Missense	proximal	1	no	10.486	10.188	EPSD;PhosphoSitePlus	ICGC;COSMIC	4.810	Down-regulation
CAMK_CAMK2_CAMK2A_ST	P07101	TH	Q9UQM7	CAMK2A	S19	K12R	12	Missense	distal	-7	no	10.486	10.552	EPSD;PhosphoSitePlus	ICGC;COSMIC	4.810	Up-regulation
CAMK_CAMK2_CAMK2A_ST	O15273	TCAP	Q9UQM7	CAMK2A	T109	R106H	106	Missense	distal	-3	no	5.609	0.112	EPSD	ICGC;COSMIC	4.810	Loss
CAMK_CAMK2_CAMK2A_ST	O15273	TCAP	Q9UQM7	CAMK2A	T109	R106L	106	Missense	distal	-3	no	5.609	0.487	EPSD	ICGC;COSMIC	4.810	Loss
CAMK_CAMK2_CAMK2A_ST	Q9UQM7	CAMK2A	Q9UQM7	CAMK2A	S257	E264K	264	Missense	distal	7	no	4.759	4.970	EPSD	ICGC	4.810	Gain
CAMK_CAMK2_CAMK2A_ST	Q9UQM7	CAMK2A	Q9UQM7	CAMK2A	T286	Q284K	284	Missense	proximal	-2	no	9.916	9.875	PhosphoSitePlus;EPSD	ICGC	4.810	Down-regulation
CAMK_CAMK2_CAMK2A_ST	Q9UQM7	CAMK2A	Q9UQM7	CAMK2A	T286	Q284H	284	Missense	proximal	-2	no	9.916	9.579	PhosphoSitePlus;EPSD	ICGC;COSMIC	4.810	Down-regulation
CAMK_CAMK2_CAMK2A_ST	Q9UQM7	CAMK2A	Q9UQM7	CAMK2A	T286	L290Q	290	Missense	distal	4	no	9.916	10.124	PhosphoSitePlus;EPSD	ICGC;COSMIC	4.810	Up-regulation
CAMK_CAMK2_CAMK2A_ST	Q9UQM7	CAMK2A	Q9UQM7	CAMK2A	T286	T286I	286	Missense	central	0	yes	9.916	0.000	PhosphoSitePlus;EPSD	ICGC;COSMIC	4.810	Loss
CAMK_CAMK2_CAMK2A_ST	Q9UQM7	CAMK2A	Q9UQM7	CAMK2A	T306	I303T	303	Missense	distal	-3	no	5.354	4.569	EPSD;PhosphoSitePlus	ICGC	4.810	Loss
CAMK_CAMK2_CAMK2A_ST	Q9UQM7	CAMK2A	Q9UQM7	CAMK2A	T306	A302D	302	Missense	distal	-4	no	5.354	5.120	EPSD;PhosphoSitePlus	ICGC;COSMIC	4.810	Down-regulation
CAMK_CAMK2_CAMK2A_ST	Q9UQM7	CAMK2A	Q9UQM7	CAMK2A	T306	R311M	311	Missense	distal	5	no	5.354	5.320	EPSD;PhosphoSitePlus	ICGC;COSMIC	4.810	Down-regulation
CAMK_CAMK2_CAMK2A_ST	Q9UQM7	CAMK2A	Q9UQM7	CAMK2A	S314	G315R	315	Missense	proximal	1	no	7.135	7.446	EPSD	ICGC;COSMIC	4.810	Up-regulation
CAMK_CAMK2_CAMK2A_ST	Q9UQM7	CAMK2A	Q9UQM7	CAMK2A	S314	R311M	311	Missense	distal	-3	no	7.135	2.317	EPSD	ICGC;COSMIC	4.810	Loss
CAMK_CAMK2_CAMK2A_ST	Q9UQM7	CAMK2A	Q9UQM7	CAMK2A	S318	G315R	315	Missense	distal	-3	no	2.700	7.298	EPSD	ICGC;COSMIC	4.810	Gain
CAMK_CAMK2_CAMK2A_ST	Q9UQM7	CAMK2A	Q9UQM7	CAMK2A	S331	S331L	331	Missense	central	0	yes	6.517	0.000	EPSD	ICGC;COSMIC	4.810	Loss
CAMK_CAMK2_CAMK2A_ST	Q9UQM7	CAMK2A	Q9UQM7	CAMK2A	S331	S324I	324	Missense	distal	-7	no	6.517	6.690	EPSD	ICGC	4.810	Up-regulation
CAMK_CAMK2_CAMK2A_ST	Q9UQM7	CAMK2A	Q9UQM7	CAMK2A	S333	S331L	331	Missense	proximal	-2	no	5.401	5.298	EPSD	ICGC;COSMIC	4.810	Down-regulation
CAMK_CAMK2_CAMK2A_ST	P28329	CHAT	Q9UQM7	CAMK2A	S125	K118N	118	Missense	distal	-7	no	6.995	7.190	EPSD	ICGC	4.810	Up-regulation
CAMK_CAMK2_CAMK2A_ST	P14921	ETS1	Q9UQM7	CAMK2A	S254	Q249R	249	Missense	distal	-5	no	6.034	6.131	EPSD	ICGC;COSMIC	4.810	Up-regulation
CAMK_CAMK2_CAMK2A_ST	P14921	ETS1	Q9UQM7	CAMK2A	S282	P281Q	281	Missense	proximal	-1	no	9.486	9.828	EPSD;PhosphoSitePlus	ICGC	4.810	Up-regulation
CAMK_CAMK2_CAMK2A_ST	P14921	ETS1	Q9UQM7	CAMK2A	S285	P281Q	281	Missense	distal	-4	no	6.022	6.227	PhosphoSitePlus;EPSD	ICGC	4.810	Up-regulation
CAMK_CAMK2_CAMK2A_ST	P35270	SPR	Q9UQM7	CAMK2A	S213	E211D	211	Missense	proximal	-2	no	9.050	8.744	PhosphoSitePlus	ICGC;COSMIC	4.810	Down-regulation
CAMK_CAMK2_CAMK2A_ST	P35270	SPR	Q9UQM7	CAMK2A	S213	E211K	211	Missense	proximal	-2	no	9.050	9.273	PhosphoSitePlus	ICGC	4.810	Up-regulation
CAMK_CAMK2_CAMK2A_ST	P35270	SPR	Q9UQM7	CAMK2A	S213	V214M	214	Missense	proximal	1	no	9.050	9.160	PhosphoSitePlus	ICGC;COSMIC	4.810	Up-regulation
CAMK_CAMK2_CAMK2A_ST	P35270	SPR	Q9UQM7	CAMK2A	S213	P216Q	216	Missense	distal	3	no	9.050	9.249	PhosphoSitePlus	ICGC;COSMIC	4.810	Up-regulation
CAMK_CAMK2_CAMK2A_ST	P35270	SPR	Q9UQM7	CAMK2A	S243	V236A	236	Missense	distal	-7	no	6.278	5.838	EPSD	ICGC;COSMIC	4.810	Down-regulation
CAMK_CAMK2_CAMK2A_ST	P43003	SLC1A3	Q9UQM7	CAMK2A	T26	G21R	21	Missense	distal	-5	no	7.224	7.118	PhosphoSitePlus;EPSD	ICGC;COSMIC	4.810	Down-regulation
CAMK_CAMK2_CAMK2A_ST	P43003	SLC1A3	Q9UQM7	CAMK2A	T26	R23H	23	Missense	distal	-3	no	7.224	1.727	PhosphoSitePlus;EPSD	ICGC;COSMIC	4.810	Loss
CAMK_CAMK2_CAMK2A_ST	P43003	SLC1A3	Q9UQM7	CAMK2A	T26	V22A	22	Missense	distal	-4	no	7.224	7.513	PhosphoSitePlus;EPSD	ICGC	4.810	Up-regulation
CAMK_CAMK2_CAMK2A_ST	P43003	SLC1A3	Q9UQM7	CAMK2A	T26	L28F	28	Missense	proximal	2	no	7.224	6.286	PhosphoSitePlus;EPSD	ICGC	4.810	Down-regulation
CAMK_CAMK2_CAMK2A_ST	P43003	SLC1A3	Q9UQM7	CAMK2A	T26	R25L	25	Missense	proximal	-1	no	7.224	7.102	PhosphoSitePlus;EPSD	ICGC;COSMIC	4.810	Down-regulation
CAMK_CAMK2_CAMK2A_ST	P43003	SLC1A3	Q9UQM7	CAMK2A	T26	V22F	22	Missense	distal	-4	no	7.224	6.987	PhosphoSitePlus;EPSD	ICGC;COSMIC	4.810	Down-regulation
CAMK_CAMK2_CAMK2A_ST	P43003	SLC1A3	Q9UQM7	CAMK2A	S82	K79R	79	Missense	distal	-3	no	4.378	6.646	EPSD	ICGC;COSMIC	4.810	Gain
CAMK_CAMK2_CAMK2A_ST	O95997	PTTG1	Q9UQM7	CAMK2A	T43	P44S	44	Missense	proximal	1	no	4.636	5.003	EPSD	ICGC;COSMIC	4.810	Gain
CAMK_CAMK2_CAMK2A_ST	O95997	PTTG1	Q9UQM7	CAMK2A	S87	K92N	92	Missense	distal	5	no	6.383	6.303	EPSD;PhosphoSitePlus	ICGC	4.810	Down-regulation
CAMK_CAMK2_CAMK2A_ST	O95997	PTTG1	Q9UQM7	CAMK2A	S87	F88Y	88	Missense	proximal	1	no	6.383	6.095	EPSD;PhosphoSitePlus	ICGC;COSMIC	4.810	Down-regulation
CAMK_CAMK2_CAMK2A_ST	O95997	PTTG1	Q9UQM7	CAMK2A	S187	P194S	194	Missense	distal	7	no	6.183	6.085	EPSD	ICGC	4.810	Down-regulation
CAMK_CAMK2_CAMK2A_ST	O95997	PTTG1	Q9UQM7	CAMK2A	S187	S184N	184	Missense	distal	-3	no	6.183	5.809	EPSD	ICGC;COSMIC	4.810	Down-regulation
CAMK_CAMK2_CAMK2A_ST	Q15796	SMAD2	Q9UQM7	CAMK2A	S47	K53N	53	Missense	distal	6	no	5.417	5.447	EPSD	ICGC;COSMIC	4.810	Up-regulation
CAMK_CAMK2_CAMK2A_ST	Q15796	SMAD2	Q9UQM7	CAMK2A	S110	R109S	109	Missense	proximal	-1	no	6.202	6.290	EPSD;PhosphoSitePlus	ICGC;COSMIC	4.810	Up-regulation
CAMK_CAMK2_CAMK2A_ST	Q15796	SMAD2	Q9UQM7	CAMK2A	S110	V117I	117	Missense	distal	7	no	6.202	6.317	EPSD;PhosphoSitePlus	ICGC	4.810	Up-regulation
CAMK_CAMK2_CAMK2A_ST	Q15796	SMAD2	Q9UQM7	CAMK2A	S110	S110Y	110	Missense	central	0	yes	6.202	0.000	EPSD;PhosphoSitePlus	ICGC	4.810	Loss
CAMK_CAMK2_CAMK2A_ST	Q15796	SMAD2	Q9UQM7	CAMK2A	S110	R109M	109	Missense	proximal	-1	no	6.202	6.283	EPSD;PhosphoSitePlus	ICGC;COSMIC	4.810	Up-regulation
CAMK_CAMK2_CAMK2A_ST	Q15796	SMAD2	Q9UQM7	CAMK2A	S110	S105Y	105	Missense	distal	-5	no	6.202	6.211	EPSD;PhosphoSitePlus	ICGC;COSMIC	4.810	Up-regulation
CAMK_CAMK2_CAMK2A_ST	Q15796	SMAD2	Q9UQM7	CAMK2A	S110	S103I	103	Missense	distal	-7	no	6.202	6.376	EPSD;PhosphoSitePlus	ICGC	4.810	Up-regulation
CAMK_CAMK2_CAMK2A_ST	Q15796	SMAD2	Q9UQM7	CAMK2A	S260	V257F	257	Missense	distal	-3	no	5.329	-3.097	PhosphoSitePlus;EPSD	ICGC;COSMIC	4.810	Loss
CAMK_CAMK2_CAMK2A_ST	Q15796	SMAD2	Q9UQM7	CAMK2A	T324	T324K	324	Missense	central	0	yes	5.120	0.000	EPSD	ICGC	4.810	Loss
CAMK_CAMK2_CAMK2A_ST	Q15796	SMAD2	Q9UQM7	CAMK2A	T430	Q429K	429	Missense	proximal	-1	no	6.049	5.955	EPSD	ICGC	4.810	Down-regulation
CAMK_CAMK2_CAMK2A_ST	P46527	CDKN1B	Q9UQM7	CAMK2A	S12	N8K	8	Missense	distal	-4	no	4.883	4.986	EPSD	ICGC;COSMIC	4.810	Up-regulation
CAMK_CAMK2_CAMK2A_ST	P46527	CDKN1B	Q9UQM7	CAMK2A	S106	V109G	109	Missense	distal	3	no	5.959	5.831	EPSD	ICGC;COSMIC	4.810	Down-regulation
CAMK_CAMK2_CAMK2A_ST	P46527	CDKN1B	Q9UQM7	CAMK2A	S106	C99W	99	Missense	distal	-7	no	5.959	6.035	EPSD	ICGC;COSMIC	4.810	Up-regulation
CAMK_CAMK2_CAMK2A_ST	P46527	CDKN1B	Q9UQM7	CAMK2A	S106	P102T	102	Missense	distal	-4	no	5.959	6.056	EPSD	ICGC;COSMIC	4.810	Up-regulation
CAMK_CAMK2_CAMK2A_ST	P46527	CDKN1B	Q9UQM7	CAMK2A	T157	Q163E	163	Missense	distal	6	no	8.037	8.049	EPSD	ICGC;COSMIC	4.810	Up-regulation
CAMK_CAMK2_CAMK2A_ST	P46527	CDKN1B	Q9UQM7	CAMK2A	T157	S160F	160	Missense	distal	3	no	8.037	7.660	EPSD	ICGC;COSMIC	4.810	Down-regulation
CAMK_CAMK2_CAMK2A_ST	P46527	CDKN1B	Q9UQM7	CAMK2A	T157	T162I	162	Missense	distal	5	no	8.037	7.929	EPSD	ICGC;COSMIC	4.810	Down-regulation
CAMK_CAMK2_CAMK2A_ST	P46527	CDKN1B	Q9UQM7	CAMK2A	S175	G182C	182	Missense	distal	7	no	5.426	5.592	EPSD	ICGC	4.810	Up-regulation
CAMK_CAMK2_CAMK2A_ST	P46527	CDKN1B	Q9UQM7	CAMK2A	S175	G177V	177	Missense	proximal	2	no	5.426	5.445	EPSD	ICGC	4.810	Up-regulation
CAMK_CAMK2_CAMK2A_ST	P46527	CDKN1B	Q9UQM7	CAMK2A	S175	S178F	178	Missense	distal	3	no	5.426	5.049	EPSD	ICGC;COSMIC	4.810	Down-regulation
CAMK_CAMK2_CAMK2A_ST	P46527	CDKN1B	Q9UQM7	CAMK2A	S183	V184M	184	Missense	proximal	1	no	5.521	5.631	EPSD	ICGC;COSMIC	4.810	Up-regulation
CAMK_CAMK2_CAMK2A_ST	P46527	CDKN1B	Q9UQM7	CAMK2A	S183	G182C	182	Missense	proximal	-1	no	5.521	5.250	EPSD	ICGC	4.810	Down-regulation
CAMK_CAMK2_CAMK2A_ST	P46527	CDKN1B	Q9UQM7	CAMK2A	S183	G177V	177	Missense	distal	-6	no	5.521	5.468	EPSD	ICGC	4.810	Down-regulation
CAMK_CAMK2_CAMK2A_ST	P46527	CDKN1B	Q9UQM7	CAMK2A	S183	S178F	178	Missense	distal	-5	no	5.521	5.539	EPSD	ICGC;COSMIC	4.810	Up-regulation
CAMK_CAMK2_CAMK2A_ST	P46527	CDKN1B	Q9UQM7	CAMK2A	T198	G192V	192	Missense	distal	-6	no	5.696	5.644	EPSD	ICGC	4.810	Down-regulation
CAMK_CAMK2_CAMK2A_ST	P46527	CDKN1B	Q9UQM7	CAMK2A	T198	P191H	191	Missense	distal	-7	no	5.696	5.475	EPSD	ICGC;COSMIC	4.810	Down-regulation
CAMK_CAMK2_CAMK2A_ST	P11831	SRF	Q9UQM7	CAMK2A	S103	G108C	108	Missense	distal	5	no	8.304	8.054	PhosphoSitePlus	ICGC	4.810	Down-regulation
CAMK_CAMK2_CAMK2A_ST	P11831	SRF	Q9UQM7	CAMK2A	S103	G97A	97	Missense	distal	-6	no	8.304	8.097	PhosphoSitePlus	ICGC	4.810	Down-regulation
CAMK_CAMK2_CAMK2A_ST	P11831	SRF	Q9UQM7	CAMK2A	S103	E104D	104	Missense	proximal	1	no	8.304	7.790	PhosphoSitePlus	ICGC;COSMIC	4.810	Down-regulation
CAMK_CAMK2_CAMK2A_ST	P11831	SRF	Q9UQM7	CAMK2A	S372	P366L	366	Missense	distal	-6	no	4.910	4.915	EPSD	ICGC;COSMIC	4.810	Up-regulation
CAMK_CAMK2_CAMK2A_ST	Q9NQC7	CYLD	Q9UQM7	CAMK2A	S62	V55M	55	Missense	distal	-7	no	7.149	6.919	EPSD	ICGC;COSMIC;GDSC;CCLE	4.810	Down-regulation
CAMK_CAMK2_CAMK2A_ST	Q9NQC7	CYLD	Q9UQM7	CAMK2A	S361	D364N	364	Missense	distal	3	no	4.844	4.716	EPSD	ICGC;COSMIC	4.810	Loss
CAMK_CAMK2_CAMK2A_ST	Q9NQC7	CYLD	Q9UQM7	CAMK2A	S362	D364N	364	Missense	proximal	2	no	5.998	4.987	PhosphoSitePlus;EPSD	ICGC;COSMIC	4.810	Down-regulation
CAMK_CAMK2_CAMK2A_ST	Q9NQC7	CYLD	Q9UQM7	CAMK2A	S547	R544K	544	Missense	distal	-3	no	6.832	4.564	EPSD	ICGC	4.810	Loss
CAMK_CAMK2_CAMK2A_ST	Q9NQC7	CYLD	Q9UQM7	CAMK2A	S560	N559K	559	Missense	proximal	-1	no	8.079	8.278	EPSD	ICGC;COSMIC	4.810	Up-regulation
CAMK_CAMK2_CAMK2A_ST	Q9NQC7	CYLD	Q9UQM7	CAMK2A	S560	A562E	562	Missense	proximal	2	no	8.079	8.965	EPSD	ICGC;COSMIC	4.810	Up-regulation
CAMK_CAMK2_CAMK2A_ST	Q9NQC7	CYLD	Q9UQM7	CAMK2A	S772	P771S	771	Missense	proximal	-1	no	5.259	5.445	EPSD;PhosphoSitePlus	ICGC;COSMIC;GDSC	4.810	Up-regulation
CAMK_CAMK2_CAMK2A_ST	Q92736	RYR2	Q9UQM7	CAMK2A	S2808	V2815A	2815	Missense	distal	7	no	8.011	7.982	EPSD;PhosphoSitePlus	ICGC;COSMIC	4.810	Down-regulation
CAMK_CAMK2_CAMK2A_ST	Q92736	RYR2	Q9UQM7	CAMK2A	S2814	V2815A	2815	Missense	proximal	1	no	6.412	6.061	PhosphoSitePlus;EPSD	ICGC;COSMIC	4.810	Down-regulation
CAMK_CAMK2_CAMK2A_ST	Q9UQL6	HDAC5	Q9UQM7	CAMK2A	S220	S225R	225	Missense	distal	5	no	6.004	5.863	EPSD	ICGC;COSMIC	4.810	Down-regulation
CAMK_CAMK2_CAMK2A_ST	P08670	VIM	Q9UQM7	CAMK2A	S26	P24L	24	Missense	proximal	-2	no	9.397	9.287	EPSD	ICGC;COSMIC	4.810	Down-regulation
CAMK_CAMK2_CAMK2A_ST	P08670	VIM	Q9UQM7	CAMK2A	S26	V31A	31	Missense	distal	5	no	9.397	9.615	EPSD	ICGC	4.810	Up-regulation
CAMK_CAMK2_CAMK2A_ST	P08670	VIM	Q9UQM7	CAMK2A	S39	R45H	45	Missense	distal	6	no	8.979	8.954	EPSD	ICGC	4.810	Down-regulation
CAMK_CAMK2_CAMK2A_ST	P08670	VIM	Q9UQM7	CAMK2A	S39	R36S	36	Missense	distal	-3	no	8.979	4.519	EPSD	ICGC;COSMIC	4.810	Loss
CAMK_CAMK2_CAMK2A_ST	P08670	VIM	Q9UQM7	CAMK2A	T48	R45H	45	Missense	distal	-3	no	8.934	3.437	EPSD	ICGC	4.810	Loss
CAMK_CAMK2_CAMK2A_ST	P08670	VIM	Q9UQM7	CAMK2A	T48	S55L	55	Missense	distal	7	no	8.934	9.097	EPSD	ICGC	4.810	Up-regulation
CAMK_CAMK2_CAMK2A_ST	P08670	VIM	Q9UQM7	CAMK2A	T48	A54G	54	Missense	distal	6	no	8.934	8.832	EPSD	ICGC	4.810	Down-regulation
CAMK_CAMK2_CAMK2A_ST	P08670	VIM	Q9UQM7	CAMK2A	S226	E229D	229	Missense	distal	3	no	7.015	6.893	EPSD	ICGC;COSMIC	4.810	Down-regulation
CAMK_CAMK2_CAMK2A_ST	P08670	VIM	Q9UQM7	CAMK2A	S316	V323L	323	Missense	distal	7	no	5.044	5.132	EPSD	ICGC;COSMIC	4.810	Up-regulation
CAMK_CAMK2_CAMK2A_ST	P08670	VIM	Q9UQM7	CAMK2A	T449	D451Y	451	Missense	proximal	2	no	5.469	1.893	EPSD	ICGC;COSMIC	4.810	Loss
CAMK_CAMK2_CAMK2A_ST	P08670	VIM	Q9UQM7	CAMK2A	T449	R450G	450	Missense	proximal	1	no	5.469	5.158	EPSD	ICGC;COSMIC	4.810	Down-regulation
CAMK_CAMK2_CAMK2A_ST	P08670	VIM	Q9UQM7	CAMK2A	T449	V447F	447	Missense	proximal	-2	no	5.469	4.994	EPSD	ICGC	4.810	Down-regulation
CAMK_CAMK2_CAMK2A_ST	O14713	ITGB1BP1	Q9UQM7	CAMK2A	S11	E18K	18	Missense	distal	7	no	8.579	8.790	EPSD	ICGC;COSMIC	4.810	Up-regulation
CAMK_CAMK2_CAMK2A_ST	O14713	ITGB1BP1	Q9UQM7	CAMK2A	S16	E18K	18	Missense	proximal	2	no	6.890	4.848	EPSD	ICGC;COSMIC	4.810	Down-regulation
CAMK_CAMK2_CAMK2A_ST	O14713	ITGB1BP1	Q9UQM7	CAMK2A	S17	E18K	18	Missense	proximal	1	no	7.238	6.983	EPSD	ICGC;COSMIC	4.810	Down-regulation
CAMK_CAMK2_CAMK2A_ST	O14713	ITGB1BP1	Q9UQM7	CAMK2A	T21	E18K	18	Missense	distal	-3	no	2.522	5.372	EPSD	ICGC;COSMIC	4.810	Gain
CAMK_CAMK2_CAMK2A_ST	O14713	ITGB1BP1	Q9UQM7	CAMK2A	S25	E18K	18	Missense	distal	-7	no	9.192	9.084	EPSD	ICGC;COSMIC	4.810	Down-regulation
CAMK_CAMK2_CAMK2A_ST	O14713	ITGB1BP1	Q9UQM7	CAMK2A	S25	S28Y	28	Missense	distal	3	no	9.192	8.853	EPSD	ICGC	4.810	Down-regulation
CAMK_CAMK2_CAMK2A_ST	O14713	ITGB1BP1	Q9UQM7	CAMK2A	T38	L33I	33	Missense	distal	-5	no	7.523	7.413	PhosphoSitePlus	ICGC;COSMIC	4.810	Down-regulation
CAMK_CAMK2_CAMK2A_ST	P31645	SLC6A4	Q9UQM7	CAMK2A	S40	Q42K	42	Missense	proximal	2	no	6.166	5.254	EPSD	ICGC;COSMIC	4.810	Down-regulation
CAMK_CAMK2_CAMK2A_ST	P31645	SLC6A4	Q9UQM7	CAMK2A	S611	K605N	605	Missense	distal	-6	no	5.054	5.173	EPSD	ICGC;COSMIC	4.810	Up-regulation
CAMK_CAMK2_CAMK2A_ST	P31645	SLC6A4	Q9UQM7	CAMK2A	S611	P617Q	617	Missense	distal	6	no	5.054	5.146	EPSD	ICGC	4.810	Up-regulation
CAMK_CAMK2_CAMK2A_ST	P31645	SLC6A4	Q9UQM7	CAMK2A	T613	P617Q	617	Missense	distal	4	no	5.213	5.383	EPSD	ICGC	4.810	Up-regulation
CAMK_CAMK2_CAMK2A_ST	P21333	FLNA	Q9UQM7	CAMK2A	S123	R116S	116	Missense	distal	-7	no	7.119	7.152	EPSD	ICGC	4.810	Up-regulation
CAMK_CAMK2_CAMK2A_ST	P21333	FLNA	Q9UQM7	CAMK2A	S123	V130M	130	Missense	distal	7	no	7.119	7.146	EPSD	ICGC	4.810	Up-regulation
CAMK_CAMK2_CAMK2A_ST	P21333	FLNA	Q9UQM7	CAMK2A	S343	Y346H	346	Missense	distal	3	no	5.546	5.844	EPSD	ICGC;COSMIC	4.810	Up-regulation
CAMK_CAMK2_CAMK2A_ST	P21333	FLNA	Q9UQM7	CAMK2A	S343	R340C	340	Missense	distal	-3	no	5.546	-0.034	EPSD	ICGC;COSMIC	4.810	Loss
CAMK_CAMK2_CAMK2A_ST	P21333	FLNA	Q9UQM7	CAMK2A	S343	F342L	342	Missense	proximal	-1	no	5.546	5.677	EPSD	ICGC;COSMIC	4.810	Up-regulation
CAMK_CAMK2_CAMK2A_ST	P21333	FLNA	Q9UQM7	CAMK2A	S343	V347I	347	Missense	distal	4	no	5.546	5.390	EPSD	ICGC;COSMIC	4.810	Down-regulation
CAMK_CAMK2_CAMK2A_ST	P21333	FLNA	Q9UQM7	CAMK2A	S377	Q378L	378	Missense	proximal	1	no	4.795	5.300	EPSD	ICGC	4.810	Gain
CAMK_CAMK2_CAMK2A_ST	P21333	FLNA	Q9UQM7	CAMK2A	S440	Q447K	447	Missense	distal	7	no	4.755	4.836	EPSD	ICGC;COSMIC	4.810	Gain
CAMK_CAMK2_CAMK2A_ST	P21333	FLNA	Q9UQM7	CAMK2A	S869	R863Q	863	Missense	distal	-6	no	5.871	5.874	EPSD	ICGC;COSMIC	4.810	Up-regulation
CAMK_CAMK2_CAMK2A_ST	P21333	FLNA	Q9UQM7	CAMK2A	S869	A872V	872	Missense	distal	3	no	5.871	5.808	EPSD	ICGC;COSMIC	4.810	Down-regulation
CAMK_CAMK2_CAMK2A_ST	P21333	FLNA	Q9UQM7	CAMK2A	S869	K874T	874	Missense	distal	5	no	5.871	5.742	EPSD	ICGC	4.810	Down-regulation
CAMK_CAMK2_CAMK2A_ST	P21333	FLNA	Q9UQM7	CAMK2A	T1286	H1292R	1292	Missense	distal	6	no	7.466	7.492	EPSD	ICGC;COSMIC	4.810	Up-regulation
CAMK_CAMK2_CAMK2A_ST	P21333	FLNA	Q9UQM7	CAMK2A	T1286	V1293I	1293	Missense	distal	7	no	7.466	7.581	EPSD	ICGC;COSMIC	4.810	Up-regulation
CAMK_CAMK2_CAMK2A_ST	P21333	FLNA	Q9UQM7	CAMK2A	S1330	P1323T	1323	Missense	distal	-7	no	5.797	5.771	EPSD	ICGC;COSMIC	4.810	Down-regulation
CAMK_CAMK2_CAMK2A_ST	P21333	FLNA	Q9UQM7	CAMK2A	S1409	G1408C	1408	Missense	proximal	-1	no	6.215	5.945	EPSD	ICGC;COSMIC	4.810	Down-regulation
CAMK_CAMK2_CAMK2A_ST	P21333	FLNA	Q9UQM7	CAMK2A	S1423	G1430S	1430	Missense	distal	7	no	5.362	5.268	EPSD	ICGC;COSMIC	4.810	Down-regulation
CAMK_CAMK2_CAMK2A_ST	P21333	FLNA	Q9UQM7	CAMK2A	S2370	A2366S	2366	Missense	distal	-4	no	5.270	5.262	EPSD	ICGC;COSMIC	4.810	Down-regulation
CAMK_CAMK2_CAMK2A_ST	Q96A00	PPP1R14A	Q9UQM7	CAMK2A	S12	R9C	9	Missense	distal	-3	no	9.367	3.786	EPSD	ICGC	4.810	Loss
CAMK_CAMK2_CAMK2A_ST	Q96A00	PPP1R14A	Q9UQM7	CAMK2A	S16	R21C	21	Missense	distal	5	no	6.911	6.619	EPSD	ICGC;COSMIC	4.810	Down-regulation
CAMK_CAMK2_CAMK2A_ST	Q96A00	PPP1R14A	Q9UQM7	CAMK2A	S16	R9C	9	Missense	distal	-7	no	6.911	7.580	EPSD	ICGC	4.810	Up-regulation
CAMK_CAMK2_CAMK2A_ST	Q96A00	PPP1R14A	Q9UQM7	CAMK2A	S18	R21C	21	Missense	distal	3	no	5.168	4.905	EPSD	ICGC;COSMIC	4.810	Down-regulation
CAMK_CAMK2_CAMK2A_ST	O43526	KCNQ2	Q9UQM7	CAMK2A	S445	A451T	451	Missense	distal	6	no	7.611	7.522	EPSD	ICGC;COSMIC	4.810	Down-regulation
CAMK_CAMK2_CAMK2A_ST	O43526	KCNQ2	Q9UQM7	CAMK2A	T857	P852S	852	Missense	distal	-5	no	7.599	7.597	EPSD	ICGC;COSMIC	4.810	Down-regulation
CAMK_CAMK2_CAMK2A_ST	Q06210	GFPT1	Q9UQM7	CAMK2A	T98	R95C	95	Missense	distal	-3	no	6.186	0.605	EPSD	ICGC;COSMIC	4.810	Loss
CAMK_CAMK2_CAMK2A_ST	Q06210	GFPT1	Q9UQM7	CAMK2A	T98	R95S	95	Missense	distal	-3	no	6.186	1.725	EPSD	ICGC;COSMIC	4.810	Loss
CAMK_CAMK2_CAMK2A_ST	Q06210	GFPT1	Q9UQM7	CAMK2A	S205	R212W	212	Missense	distal	7	no	6.530	6.845	EPSD	ICGC;COSMIC	4.810	Up-regulation
CAMK_CAMK2_CAMK2A_ST	Q06210	GFPT1	Q9UQM7	CAMK2A	S205	G200D	200	Missense	distal	-5	no	6.530	6.546	EPSD	ICGC	4.810	Up-regulation
CAMK_CAMK2_CAMK2A_ST	Q06210	GFPT1	Q9UQM7	CAMK2A	S253	R258C	258	Missense	distal	5	no	6.269	5.976	EPSD	ICGC;COSMIC	4.810	Down-regulation
CAMK_CAMK2_CAMK2A_ST	Q06210	GFPT1	Q9UQM7	CAMK2A	S253	D260H	260	Missense	distal	7	no	6.269	6.260	EPSD	ICGC;COSMIC	4.810	Down-regulation
CAMK_CAMK2_CAMK2A_ST	Q06210	GFPT1	Q9UQM7	CAMK2A	S261	R258C	258	Missense	distal	-3	no	7.159	1.578	PhosphoSitePlus	ICGC;COSMIC	4.810	Loss
CAMK_CAMK2_CAMK2A_ST	Q06210	GFPT1	Q9UQM7	CAMK2A	S261	T262K	262	Missense	proximal	1	no	7.159	7.107	PhosphoSitePlus	ICGC;COSMIC	4.810	Down-regulation
CAMK_CAMK2_CAMK2A_ST	Q06210	GFPT1	Q9UQM7	CAMK2A	S261	L265I	265	Missense	distal	4	no	7.159	7.104	PhosphoSitePlus	ICGC	4.810	Down-regulation
CAMK_CAMK2_CAMK2A_ST	Q06210	GFPT1	Q9UQM7	CAMK2A	S261	D260H	260	Missense	proximal	-1	no	7.159	7.396	PhosphoSitePlus	ICGC;COSMIC	4.810	Up-regulation
CAMK_CAMK2_CAMK2A_ST	P35222	CTNNB1	Q9UQM7	CAMK2A	T332	T332N	332	Missense	central	0	yes	6.811	0.000	EPSD;PhosphoSitePlus	ICGC;COSMIC	4.810	Loss
CAMK_CAMK2_CAMK2A_ST	O14490	DLGAP1	Q9UQM7	CAMK2A	T76	S77P	77	Missense	proximal	1	no	6.832	6.464	EPSD	ICGC;COSMIC	4.810	Down-regulation
CAMK_CAMK2_CAMK2A_ST	O14490	DLGAP1	Q9UQM7	CAMK2A	T76	Q79E	79	Missense	distal	3	no	6.832	7.040	EPSD	ICGC;COSMIC	4.810	Up-regulation
CAMK_CAMK2_CAMK2A_ST	O14490	DLGAP1	Q9UQM7	CAMK2A	S154	T150I	150	Missense	distal	-4	no	6.849	6.752	EPSD	ICGC	4.810	Down-regulation
CAMK_CAMK2_CAMK2A_ST	O14490	DLGAP1	Q9UQM7	CAMK2A	S169	G165R	165	Missense	distal	-4	no	4.624	4.832	EPSD	ICGC;COSMIC	4.810	Gain
CAMK_CAMK2_CAMK2A_ST	O14490	DLGAP1	Q9UQM7	CAMK2A	S233	E238D	238	Missense	distal	5	no	6.191	6.129	EPSD	ICGC;COSMIC	4.810	Down-regulation
CAMK_CAMK2_CAMK2A_ST	O14490	DLGAP1	Q9UQM7	CAMK2A	S515	R512Q	512	Missense	distal	-3	no	7.871	4.299	EPSD	ICGC;COSMIC	4.810	Loss
CAMK_CAMK2_CAMK2A_ST	P09917	ALOX5	Q9UQM7	CAMK2A	T105	G106S	106	Missense	proximal	1	no	6.840	7.339	EPSD	ICGC;COSMIC	4.810	Up-regulation
CAMK_CAMK2_CAMK2A_ST	P09917	ALOX5	Q9UQM7	CAMK2A	S272	Q278H	278	Missense	distal	6	no	11.464	11.433	EPSD;PhosphoSitePlus	ICGC;COSMIC	4.810	Down-regulation
CAMK_CAMK2_CAMK2A_ST	P09917	ALOX5	Q9UQM7	CAMK2A	T445	A447D	447	Missense	proximal	2	no	3.355	5.157	EPSD	ICGC;COSMIC	4.810	Gain
CAMK_CAMK2_CAMK2A_ST	P09917	ALOX5	Q9UQM7	CAMK2A	T486	T484M	484	Missense	proximal	-2	no	6.904	7.131	EPSD	ICGC;COSMIC	4.810	Up-regulation
CAMK_CAMK2_CAMK2A_ST	P09917	ALOX5	Q9UQM7	CAMK2A	S524	M518T	518	Missense	distal	-6	no	6.284	6.435	EPSD	ICGC;COSMIC	4.810	Up-regulation
CAMK_CAMK2_CAMK2A_ST	P09917	ALOX5	Q9UQM7	CAMK2A	S524	R519Q	519	Missense	distal	-5	no	6.284	6.187	EPSD	ICGC;COSMIC	4.810	Down-regulation
CAMK_CAMK2_CAMK2A_ST	P09917	ALOX5	Q9UQM7	CAMK2A	S524	R519L	519	Missense	distal	-5	no	6.284	6.264	EPSD	ICGC;COSMIC	4.810	Down-regulation
CAMK_CAMK2_CAMK2A_ST	P41134	ID1	Q9UQM7	CAMK2A	S36	G29C	29	Missense	distal	-7	no	5.316	5.653	PhosphoSitePlus	ICGC	4.810	Up-regulation
CAMK_CAMK2_CAMK2A_ST	P41134	ID1	Q9UQM7	CAMK2A	S36	E30D	30	Missense	distal	-6	no	5.316	5.513	PhosphoSitePlus	ICGC	4.810	Up-regulation
CAMK_CAMK2_CAMK2A_ST	P55055	NR1H2	Q9UQM7	CAMK2A	S426	R428C	428	Missense	proximal	2	no	6.813	6.367	PhosphoSitePlus	ICGC;COSMIC	4.810	Down-regulation
CAMK_CAMK2_CAMK2A_ST	P55055	NR1H2	Q9UQM7	CAMK2A	S426	R419C	419	Missense	distal	-7	no	6.813	7.481	PhosphoSitePlus	ICGC;COSMIC	4.810	Up-regulation
CAMK_CAMK2_CAMK2A_ST	P55055	NR1H2	Q9UQM7	CAMK2A	S426	S431I	431	Missense	distal	5	no	6.813	6.544	PhosphoSitePlus	ICGC;COSMIC	4.810	Down-regulation
CAMK_CAMK2_CAMK2A_ST	P55055	NR1H2	Q9UQM7	CAMK2A	S426	T429A	429	Missense	distal	3	no	6.813	7.048	PhosphoSitePlus	ICGC;COSMIC	4.810	Up-regulation
CAMK_CAMK2_CAMK2A_ST	P51790	CLCN3	Q9UQM7	CAMK2A	S109	R103S	103	Missense	distal	-6	no	8.332	8.376	PhosphoSitePlus	ICGC	4.810	Up-regulation
CAMK_CAMK2_CAMK2A_ST	P51790	CLCN3	Q9UQM7	CAMK2A	S109	N108I	108	Missense	proximal	-1	no	8.332	8.294	PhosphoSitePlus	ICGC	4.810	Down-regulation
CAMK_CAMK2_CAMK2A_ST	P40189	IL6ST	Q9UQM7	CAMK2A	T890	G883E	883	Missense	distal	-7	no	7.308	7.019	EPSD	ICGC;COSMIC	4.810	Down-regulation
CAMK_CAMK2_CAMK2A_ST	Q00613	HSF1	Q9UQM7	CAMK2A	S230	P223L	223	Missense	distal	-7	no	10.324	10.290	PhosphoSitePlus	ICGC	4.810	Down-regulation
CAMK_CAMK2_CAMK2A_ST	Q00613	HSF1	Q9UQM7	CAMK2A	S283	A278T	278	Missense	distal	-5	no	6.199	6.190	EPSD	ICGC	4.810	Down-regulation
CAMK_CAMK2_CAMK2A_ST	Q4G163	FBXO43	Q9UQM7	CAMK2A	T234	T234K	234	Missense	central	0	yes	6.441	0.000	PhosphoSitePlus	ICGC;COSMIC	4.810	Loss
CAMK_CAMK2_CAMK2A_ST	Q4G163	FBXO43	Q9UQM7	CAMK2A	T234	D237Y	237	Missense	distal	3	no	6.441	6.089	PhosphoSitePlus	ICGC;COSMIC	4.810	Down-regulation
CAMK_CAMK2_CAMK2A_ST	Q4G163	FBXO43	Q9UQM7	CAMK2A	S385	L387H	387	Missense	proximal	2	no	6.448	6.117	EPSD	ICGC;COSMIC	4.810	Down-regulation
CAMK_CAMK2_CAMK2A_ST	Q4G163	FBXO43	Q9UQM7	CAMK2A	S385	R388Q	388	Missense	distal	3	no	6.448	6.470	EPSD	ICGC;CCLE	4.810	Up-regulation
CAMK_CAMK2_CAMK2A_ST	Q4G163	FBXO43	Q9UQM7	CAMK2A	S385	S392L	392	Missense	distal	7	no	6.448	6.611	EPSD	ICGC;COSMIC	4.810	Up-regulation
CAMK_CAMK2_CAMK2A_ST	Q4G163	FBXO43	Q9UQM7	CAMK2A	S698	S701N	701	Missense	distal	3	no	4.896	4.782	EPSD	ICGC;COSMIC	4.810	Loss
CAMK_CAMK2_CAMK2A_ST	Q4G163	FBXO43	Q9UQM7	CAMK2A	S698	P696T	696	Missense	proximal	-2	no	4.896	4.846	EPSD	ICGC	4.810	Down-regulation
CAMK_CAMK2_CAMK2A_ST	P55042	RRAD	Q9UQM7	CAMK2A	S214	R219Q	219	Missense	distal	5	no	11.533	11.532	EPSD	ICGC;COSMIC	4.810	Down-regulation
CAMK_CAMK2_CAMK2A_ST	P55042	RRAD	Q9UQM7	CAMK2A	S214	A220T	220	Missense	distal	6	no	11.533	11.444	EPSD	ICGC;COSMIC	4.810	Down-regulation
CAMK_CAMK2_CAMK2A_ST	P55042	RRAD	Q9UQM7	CAMK2A	S214	R211S	211	Missense	distal	-3	no	11.533	7.073	EPSD	ICGC;COSMIC	4.810	Down-regulation
CAMK_CAMK2_CAMK2A_ST	P55042	RRAD	Q9UQM7	CAMK2A	S257	R254C	254	Missense	distal	-3	no	7.537	1.957	EPSD	ICGC;COSMIC	4.810	Loss
CAMK_CAMK2_CAMK2A_ST	P55042	RRAD	Q9UQM7	CAMK2A	S257	R264W	264	Missense	distal	7	no	7.537	7.853	EPSD	ICGC;COSMIC	4.810	Up-regulation
CAMK_CAMK2_CAMK2A_ST	P55042	RRAD	Q9UQM7	CAMK2A	S273	R280C	280	Missense	distal	7	no	8.905	9.061	PhosphoSitePlus	ICGC;COSMIC;GDSC;CCLE	4.810	Up-regulation
CAMK_CAMK2_CAMK2A_ST	P55042	RRAD	Q9UQM7	CAMK2A	S273	A278V	278	Missense	distal	5	no	8.905	8.687	PhosphoSitePlus	ICGC;COSMIC	4.810	Down-regulation
CAMK_CAMK2_CAMK2A_ST	P55042	RRAD	Q9UQM7	CAMK2A	S299	A297T	297	Missense	proximal	-2	no	8.617	8.467	EPSD	ICGC;COSMIC	4.810	Down-regulation
CAMK_CAMK2_CAMK2A_ST	P55042	RRAD	Q9UQM7	CAMK2A	S301	A297T	297	Missense	distal	-4	no	6.107	5.817	EPSD	ICGC;COSMIC	4.810	Down-regulation
CAMK_CAMK2_CAMK2A_ST	Q96PM5	RCHY1	Q9UQM7	CAMK2A	S257	G252E	252	Missense	distal	-5	no	8.323	8.175	EPSD	ICGC;COSMIC	4.810	Down-regulation
CAMK_CAMK2_CAMK2A_ST	P16949	STMN1	Q9UQM7	CAMK2A	S63	S63F	63	Missense	central	0	yes	9.684	0.000	EPSD	ICGC;COSMIC	4.810	Loss
CAMK_CAMK2_CAMK2A_ST	P16949	STMN1	Q9UQM7	CAMK2A	S139	S139C	139	Missense	central	0	yes	6.940	0.000	EPSD	ICGC;COSMIC	4.810	Loss
CAMK_CAMK2_CAMK2A_ST	P16949	STMN1	Q9UQM7	CAMK2A	S139	V133A	133	Missense	distal	-6	no	6.940	6.785	EPSD	ICGC;COSMIC;GDSC;CCLE	4.810	Down-regulation
CAMK_CAMK2_CAMK2A_ST	P16949	STMN1	Q9UQM7	CAMK2A	S139	R134Q	134	Missense	distal	-5	no	6.940	6.843	EPSD	ICGC;COSMIC	4.810	Down-regulation
CAMK_CAMK2_CAMK2A_ST	P16949	STMN1	Q9UQM7	CAMK2A	S139	D144E	144	Missense	distal	5	no	6.940	7.002	EPSD	ICGC	4.810	Up-regulation
CAMK_CAMK2_CAMK2A_ST	P16949	STMN1	Q9UQM7	CAMK2A	S139	A143D	143	Missense	distal	4	no	6.940	6.886	EPSD	ICGC;COSMIC	4.810	Down-regulation
CAMK_CAMK2_CAMK2A_ST	P16949	STMN1	Q9UQM7	CAMK2A	S139	T146N	146	Missense	distal	7	no	6.940	6.892	EPSD	ICGC;COSMIC	4.810	Down-regulation
CAMK_CAMK2_CAMK2A_ST	P35372	OPRM1	Q9UQM7	CAMK2A	S263	R260H	260	Missense	distal	-3	no	6.592	1.095	EPSD	ICGC;COSMIC;CCLE	4.810	Loss
CAMK_CAMK2_CAMK2A_ST	P35372	OPRM1	Q9UQM7	CAMK2A	S263	R265C	265	Missense	proximal	2	no	6.592	6.146	EPSD	ICGC;COSMIC	4.810	Down-regulation
CAMK_CAMK2_CAMK2A_ST	P35372	OPRM1	Q9UQM7	CAMK2A	S263	L259F	259	Missense	distal	-4	no	6.592	6.372	EPSD	ICGC;COSMIC	4.810	Down-regulation
CAMK_CAMK2_CAMK2A_ST	P35372	OPRM1	Q9UQM7	CAMK2A	S263	L259S	259	Missense	distal	-4	no	6.592	6.890	EPSD	ICGC;COSMIC	4.810	Up-regulation
CAMK_CAMK2_CAMK2A_ST	P35372	OPRM1	Q9UQM7	CAMK2A	S263	R265H	265	Missense	proximal	2	no	6.592	5.524	EPSD	ICGC;COSMIC	4.810	Down-regulation
CAMK_CAMK2_CAMK2A_ST	P35372	OPRM1	Q9UQM7	CAMK2A	S263	L261F	261	Missense	proximal	-2	no	6.592	5.909	EPSD	ICGC	4.810	Down-regulation
CAMK_CAMK2_CAMK2A_ST	P35372	OPRM1	Q9UQM7	CAMK2A	S263	S268F	268	Missense	distal	5	no	6.592	6.331	EPSD	ICGC;COSMIC	4.810	Down-regulation
CAMK_CAMK2_CAMK2A_ST	P35372	OPRM1	Q9UQM7	CAMK2A	S268	E272G	272	Missense	distal	4	no	6.827	6.601	PhosphoSitePlus	ICGC;COSMIC	4.810	Down-regulation
CAMK_CAMK2_CAMK2A_ST	P35372	OPRM1	Q9UQM7	CAMK2A	S268	R265C	265	Missense	distal	-3	no	6.827	1.247	PhosphoSitePlus	ICGC;COSMIC	4.810	Loss
CAMK_CAMK2_CAMK2A_ST	P35372	OPRM1	Q9UQM7	CAMK2A	S268	R265H	265	Missense	distal	-3	no	6.827	1.330	PhosphoSitePlus	ICGC;COSMIC	4.810	Loss
CAMK_CAMK2_CAMK2A_ST	P35372	OPRM1	Q9UQM7	CAMK2A	S268	L261F	261	Missense	distal	-7	no	6.827	7.294	PhosphoSitePlus	ICGC	4.810	Up-regulation
CAMK_CAMK2_CAMK2A_ST	P35372	OPRM1	Q9UQM7	CAMK2A	S268	S268F	268	Missense	central	0	yes	6.827	0.000	PhosphoSitePlus	ICGC;COSMIC	4.810	Loss
CAMK_CAMK2_CAMK2A_ST	P35372	OPRM1	Q9UQM7	CAMK2A	S357	N359D	359	Missense	proximal	2	no	3.936	4.947	EPSD	ICGC;COSMIC	4.810	Gain
CAMK_CAMK2_CAMK2A_ST	P35372	OPRM1	Q9UQM7	CAMK2A	S365	S358F	358	Missense	distal	-7	no	4.612	5.173	EPSD	ICGC;COSMIC	4.810	Gain
CAMK_CAMK2_CAMK2A_ST	P35372	OPRM1	Q9UQM7	CAMK2A	T372	R373T	373	Missense	proximal	1	no	9.812	9.881	EPSD	ICGC;COSMIC	4.810	Up-regulation
CAMK_CAMK2_CAMK2A_ST	P35372	OPRM1	Q9UQM7	CAMK2A	T372	R369C	369	Missense	distal	-3	no	9.812	4.231	EPSD	ICGC;COSMIC	4.810	Loss
CAMK_CAMK2_CAMK2A_ST	P35372	OPRM1	Q9UQM7	CAMK2A	T372	R367Q	367	Missense	distal	-5	no	9.812	9.715	EPSD	ICGC;COSMIC	4.810	Down-regulation
CAMK_CAMK2_CAMK2A_ST	P35372	OPRM1	Q9UQM7	CAMK2A	T372	R369H	369	Missense	distal	-3	no	9.812	4.315	EPSD	ICGC;COSMIC	4.810	Loss
CAMK_CAMK2_CAMK2A_ST	P35372	OPRM1	Q9UQM7	CAMK2A	T372	R367L	367	Missense	distal	-5	no	9.812	9.792	EPSD	ICGC;COSMIC;CCLE	4.810	Down-regulation
CAMK_CAMK2_CAMK2A_ST	P35372	OPRM1	Q9UQM7	CAMK2A	T372	R369S	369	Missense	distal	-3	no	9.812	5.352	EPSD	ICGC;COSMIC	4.810	Down-regulation
CAMK_CAMK2_CAMK2A_ST	P35372	OPRM1	Q9UQM7	CAMK2A	T372	N371H	371	Missense	proximal	-1	no	9.812	10.005	EPSD	ICGC;COSMIC	4.810	Up-regulation
CAMK_CAMK2_CAMK2A_ST	P35372	OPRM1	Q9UQM7	CAMK2A	T372	T372I	372	Missense	central	0	yes	9.812	0.000	EPSD	ICGC;COSMIC	4.810	Loss
CAMK_CAMK2_CAMK2A_ST	P35372	OPRM1	Q9UQM7	CAMK2A	T372	R369L	369	Missense	distal	-3	no	9.812	4.690	EPSD	ICGC;COSMIC	4.810	Loss
CAMK_CAMK2_CAMK2A_ST	P35372	OPRM1	Q9UQM7	CAMK2A	T372	T378M	378	Missense	distal	6	no	9.812	9.822	EPSD	ICGC;COSMIC	4.810	Up-regulation
CAMK_CAMK2_CAMK2A_ST	P35372	OPRM1	Q9UQM7	CAMK2A	T372	H375N	375	Missense	distal	3	no	9.812	9.739	EPSD	ICGC	4.810	Down-regulation
CAMK_CAMK2_CAMK2A_ST	Q9Y496	KIF3A	Q9UQM7	CAMK2A	S207	L201I	201	Missense	distal	-6	no	6.388	6.310	EPSD	ICGC;COSMIC	4.810	Down-regulation
CAMK_CAMK2_CAMK2A_ST	Q9Y496	KIF3A	Q9UQM7	CAMK2A	S207	N214K	214	Missense	distal	7	no	6.388	6.409	EPSD	ICGC;COSMIC	4.810	Up-regulation
CAMK_CAMK2_CAMK2A_ST	Q9Y496	KIF3A	Q9UQM7	CAMK2A	S217	N214K	214	Missense	distal	-3	no	4.684	7.251	EPSD	ICGC;COSMIC	4.810	Gain
CAMK_CAMK2_CAMK2A_ST	Q9Y496	KIF3A	Q9UQM7	CAMK2A	S534	T533N	533	Missense	proximal	-1	no	6.134	6.159	EPSD	ICGC	4.810	Up-regulation
CAMK_CAMK2_CAMK2A_ST	Q9Y496	KIF3A	Q9UQM7	CAMK2A	S534	T533S	533	Missense	proximal	-1	no	6.134	6.294	EPSD	ICGC;COSMIC	4.810	Up-regulation
CAMK_CAMK2_CAMK2A_ST	Q9Y496	KIF3A	Q9UQM7	CAMK2A	S534	D527N	527	Missense	distal	-7	no	6.134	6.019	EPSD	ICGC	4.810	Down-regulation
CAMK_CAMK2_CAMK2A_ST	Q9Y496	KIF3A	Q9UQM7	CAMK2A	S534	E529G	529	Missense	distal	-5	no	6.134	6.282	EPSD	ICGC	4.810	Up-regulation
CAMK_CAMK2_CAMK2A_ST	Q9Y496	KIF3A	Q9UQM7	CAMK2A	T633	R630M	630	Missense	distal	-3	no	6.443	1.625	EPSD	ICGC;COSMIC	4.810	Loss
CAMK_CAMK2_CAMK2A_ST	Q9Y496	KIF3A	Q9UQM7	CAMK2A	T633	P634Q	634	Missense	proximal	1	no	6.443	6.596	EPSD	ICGC;COSMIC	4.810	Up-regulation
CAMK_CAMK2_CAMK2A_ST	Q9Y496	KIF3A	Q9UQM7	CAMK2A	T633	K639R	639	Missense	distal	6	no	6.443	6.476	EPSD	ICGC;COSMIC	4.810	Up-regulation
CAMK_CAMK2_CAMK2A_ST	Q9Y496	KIF3A	Q9UQM7	CAMK2A	T672	R671Q	671	Missense	proximal	-1	no	7.746	7.991	EPSD	ICGC	4.810	Up-regulation
CAMK_CAMK2_CAMK2A_ST	Q9Y496	KIF3A	Q9UQM7	CAMK2A	T672	T672N	672	Missense	central	0	yes	7.746	0.000	EPSD	ICGC	4.810	Loss
CAMK_CAMK2_CAMK2A_ST	Q9Y496	KIF3A	Q9UQM7	CAMK2A	T672	P670T	670	Missense	proximal	-2	no	7.746	7.696	EPSD	ICGC	4.810	Down-regulation
CAMK_CAMK2_CAMK2A_ST	Q9Y496	KIF3A	Q9UQM7	CAMK2A	S687	I694M	694	Missense	distal	7	no	9.452	9.364	PhosphoSitePlus	ICGC	4.810	Down-regulation
CAMK_CAMK2_CAMK2A_ST	Q9Y496	KIF3A	Q9UQM7	CAMK2A	S687	P690S	690	Missense	distal	3	no	9.452	9.723	PhosphoSitePlus	ICGC;COSMIC	4.810	Up-regulation
CAMK_CAMK2_CAMK2A_ST	Q9Y496	KIF3A	Q9UQM7	CAMK2A	S687	R686H	686	Missense	proximal	-1	no	9.452	9.597	PhosphoSitePlus	ICGC;COSMIC	4.810	Up-regulation
CAMK_CAMK2_CAMK2A_ST	Q9Y4D2	DAGLA	Q9UQM7	CAMK2A	S727	Q728P	728	Missense	proximal	1	no	5.801	5.648	EPSD	ICGC;COSMIC	4.810	Down-regulation
CAMK_CAMK2_CAMK2A_ST	Q9Y4D2	DAGLA	Q9UQM7	CAMK2A	S729	Q728P	728	Missense	proximal	-1	no	7.741	7.399	EPSD	ICGC;COSMIC	4.810	Down-regulation
CAMK_CAMK2_CAMK2A_ST	Q9Y4D2	DAGLA	Q9UQM7	CAMK2A	S732	S737L	737	Missense	distal	5	no	5.124	4.835	EPSD	ICGC;COSMIC	4.810	Down-regulation
CAMK_CAMK2_CAMK2A_ST	Q9Y4D2	DAGLA	Q9UQM7	CAMK2A	S732	Q728P	728	Missense	distal	-4	no	5.124	4.919	EPSD	ICGC;COSMIC	4.810	Down-regulation
CAMK_CAMK2_CAMK2A_ST	Q9Y4D2	DAGLA	Q9UQM7	CAMK2A	S743	S737L	737	Missense	distal	-6	no	5.894	5.948	EPSD	ICGC;COSMIC	4.810	Up-regulation
CAMK_CAMK2_CAMK2A_ST	Q9Y4D2	DAGLA	Q9UQM7	CAMK2A	S798	G799A	799	Missense	proximal	1	no	6.335	6.616	EPSD	ICGC;COSMIC	4.810	Up-regulation
CAMK_CAMK2_CAMK2A_ST	Q9Y4D2	DAGLA	Q9UQM7	CAMK2A	S798	R795C	795	Missense	distal	-3	no	6.335	0.754	EPSD	ICGC;COSMIC	4.810	Loss
CAMK_CAMK2_CAMK2A_ST	Q9Y4D2	DAGLA	Q9UQM7	CAMK2A	S850	Q854L	854	Missense	distal	4	no	5.879	5.672	EPSD	ICGC	4.810	Down-regulation
CAMK_CAMK2_CAMK2A_ST	Q9Y4D2	DAGLA	Q9UQM7	CAMK2A	S850	K848T	848	Missense	proximal	-2	no	5.879	5.589	EPSD	ICGC	4.810	Down-regulation
CAMK_CAMK2_CAMK2A_ST	Q9Y4D2	DAGLA	Q9UQM7	CAMK2A	S872	P867L	867	Missense	distal	-5	no	7.599	7.506	EPSD	ICGC	4.810	Down-regulation
CAMK_CAMK2_CAMK2A_ST	Q9Y4D2	DAGLA	Q9UQM7	CAMK2A	S929	N922S	922	Missense	distal	-7	no	6.348	6.251	EPSD	ICGC;COSMIC	4.810	Down-regulation
CAMK_CAMK2_CAMK2A_ST	Q9Y4D2	DAGLA	Q9UQM7	CAMK2A	S929	D932E	932	Missense	distal	3	no	6.348	6.471	EPSD	ICGC	4.810	Up-regulation
CAMK_CAMK2_CAMK2A_ST	Q9Y4D2	DAGLA	Q9UQM7	CAMK2A	S1030	H1027Q	1027	Missense	distal	-3	no	4.051	5.977	EPSD	ICGC;COSMIC	4.810	Gain
CAMK_CAMK2_CAMK2A_ST	Q9BXL7	CARD11	Q9UQM7	CAMK2A	S116	G123S	123	Missense	distal	7	no	7.539	7.444	PhosphoSitePlus	ICGC;COSMIC	4.810	Down-regulation
CAMK_CAMK2_CAMK2A_ST	Q9BXL7	CARD11	Q9UQM7	CAMK2A	S116	I118V	118	Missense	proximal	2	no	7.539	7.634	PhosphoSitePlus	ICGC;COSMIC	4.810	Up-regulation
CAMK_CAMK2_CAMK2A_ST	Q9BXL7	CARD11	Q9UQM7	CAMK2A	S116	S116A	116	Missense	central	0	yes	7.539	0.000	PhosphoSitePlus	ICGC;COSMIC	4.810	Loss
CAMK_CAMK2_CAMK2A_ST	Q9BXL7	CARD11	Q9UQM7	CAMK2A	S116	P111S	111	Missense	distal	-5	no	7.539	7.537	PhosphoSitePlus	ICGC;COSMIC	4.810	Down-regulation
CAMK_CAMK2_CAMK2A_ST	Q9BXL7	CARD11	Q9UQM7	CAMK2A	S116	F115I	115	Missense	proximal	-1	no	7.539	7.706	PhosphoSitePlus	ICGC;COSMIC	4.810	Up-regulation
CAMK_CAMK2_CAMK2A_ST	Q9BXL7	CARD11	Q9UQM7	CAMK2A	T117	G123S	123	Missense	distal	6	no	6.080	6.139	EPSD	ICGC;COSMIC	4.810	Up-regulation
CAMK_CAMK2_CAMK2A_ST	Q9BXL7	CARD11	Q9UQM7	CAMK2A	T117	I118V	118	Missense	proximal	1	no	6.080	5.871	EPSD	ICGC;COSMIC	4.810	Down-regulation
CAMK_CAMK2_CAMK2A_ST	Q9BXL7	CARD11	Q9UQM7	CAMK2A	T117	S116A	116	Missense	proximal	-1	no	6.080	6.135	EPSD	ICGC;COSMIC	4.810	Up-regulation
CAMK_CAMK2_CAMK2A_ST	Q9BXL7	CARD11	Q9UQM7	CAMK2A	T117	P111S	111	Missense	distal	-6	no	6.080	6.030	EPSD	ICGC;COSMIC	4.810	Down-regulation
CAMK_CAMK2_CAMK2A_ST	Q9BXL7	CARD11	Q9UQM7	CAMK2A	T117	F115I	115	Missense	proximal	-2	no	6.080	6.797	EPSD	ICGC;COSMIC	4.810	Up-regulation
CAMK_CAMK2_CAMK2A_ST	Q9BXL7	CARD11	Q9UQM7	CAMK2A	S439	S439A	439	Missense	central	0	yes	8.768	0.000	EPSD	ICGC;COSMIC	4.810	Loss
CAMK_CAMK2_CAMK2A_ST	Q9BXL7	CARD11	Q9UQM7	CAMK2A	S439	S433G	433	Missense	distal	-6	no	8.768	8.861	EPSD	ICGC;COSMIC	4.810	Up-regulation
CAMK_CAMK2_CAMK2A_ST	Q9BXL7	CARD11	Q9UQM7	CAMK2A	S439	D446E	446	Missense	distal	7	no	8.768	8.560	EPSD	ICGC	4.810	Down-regulation
CAMK_CAMK2_CAMK2A_ST	Q9BXL7	CARD11	Q9UQM7	CAMK2A	S439	D441E	441	Missense	proximal	2	no	8.768	7.852	EPSD	ICGC;COSMIC	4.810	Down-regulation
CAMK_CAMK2_CAMK2A_ST	Q9BXL7	CARD11	Q9UQM7	CAMK2A	S439	D446N	446	Missense	distal	7	no	8.768	8.750	EPSD	ICGC	4.810	Down-regulation
CAMK_CAMK2_CAMK2A_ST	Q9BXL7	CARD11	Q9UQM7	CAMK2A	S512	S512P	512	Missense	central	0	yes	6.859	0.000	EPSD	ICGC;COSMIC	4.810	Loss
CAMK_CAMK2_CAMK2A_ST	Q9BXL7	CARD11	Q9UQM7	CAMK2A	S512	T519K	519	Missense	distal	7	no	6.859	6.831	EPSD	ICGC	4.810	Down-regulation
CAMK_CAMK2_CAMK2A_ST	Q9BXL7	CARD11	Q9UQM7	CAMK2A	S512	Q508H	508	Missense	distal	-4	no	6.859	6.840	EPSD	ICGC;COSMIC	4.810	Down-regulation
CAMK_CAMK2_CAMK2A_ST	Q9BXL7	CARD11	Q9UQM7	CAMK2A	S520	Q523K	523	Missense	distal	3	no	5.861	5.904	EPSD	ICGC;COSMIC	4.810	Up-regulation
CAMK_CAMK2_CAMK2A_ST	Q9BXL7	CARD11	Q9UQM7	CAMK2A	S520	T519K	519	Missense	proximal	-1	no	5.861	6.084	EPSD	ICGC	4.810	Up-regulation
CAMK_CAMK2_CAMK2A_ST	Q9BXL7	CARD11	Q9UQM7	CAMK2A	S520	G526W	526	Missense	distal	6	no	5.861	5.684	EPSD	ICGC;COSMIC	4.810	Down-regulation
CAMK_CAMK2_CAMK2A_ST	Q9BXL7	CARD11	Q9UQM7	CAMK2A	S558	A565S	565	Missense	distal	7	no	6.946	6.900	EPSD	ICGC;COSMIC	4.810	Down-regulation
CAMK_CAMK2_CAMK2A_ST	Q9BXL7	CARD11	Q9UQM7	CAMK2A	S558	Q552K	552	Missense	distal	-6	no	6.946	6.971	EPSD	ICGC	4.810	Up-regulation
CAMK_CAMK2_CAMK2A_ST	Q9BXL7	CARD11	Q9UQM7	CAMK2A	S558	P553L	553	Missense	distal	-5	no	6.946	6.853	EPSD	ICGC	4.810	Down-regulation
CAMK_CAMK2_CAMK2A_ST	Q9BXL7	CARD11	Q9UQM7	CAMK2A	S618	H623Q	623	Missense	distal	5	no	5.235	5.120	EPSD	ICGC	4.810	Down-regulation
CAMK_CAMK2_CAMK2A_ST	Q9BXL7	CARD11	Q9UQM7	CAMK2A	S618	S625Y	625	Missense	distal	7	no	5.235	5.409	EPSD	ICGC;COSMIC	4.810	Up-regulation
CAMK_CAMK2_CAMK2A_ST	Q9BXL7	CARD11	Q9UQM7	CAMK2A	S618	S620F	620	Missense	proximal	2	no	5.235	3.984	EPSD	ICGC	4.810	Loss
CAMK_CAMK2_CAMK2A_ST	Q9BXL7	CARD11	Q9UQM7	CAMK2A	S644	N637K	637	Missense	distal	-7	no	8.796	8.601	EPSD	ICGC	4.810	Down-regulation
CAMK_CAMK2_CAMK2A_ST	Q9BXL7	CARD11	Q9UQM7	CAMK2A	S644	R650W	650	Missense	distal	6	no	8.796	8.557	EPSD	ICGC;COSMIC;GDSC;CCLE	4.810	Down-regulation
CAMK_CAMK2_CAMK2A_ST	Q9BXL7	CARD11	Q9UQM7	CAMK2A	S923	E917V	917	Missense	distal	-6	no	6.853	7.011	EPSD	ICGC;COSMIC	4.810	Up-regulation
CAMK_CAMK2_CAMK2A_ST	Q9BXL7	CARD11	Q9UQM7	CAMK2A	T1020	R1027L	1027	Missense	distal	7	no	6.645	6.704	EPSD	ICGC	4.810	Up-regulation
CAMK_CAMK2_CAMK2A_ST	Q9BXL7	CARD11	Q9UQM7	CAMK2A	T1020	S1026Y	1026	Missense	distal	6	no	6.645	6.537	EPSD	ICGC;COSMIC	4.810	Down-regulation
CAMK_CAMK2_CAMK2A_ST	Q01970	PLCB3	Q9UQM7	CAMK2A	S26	G25W	25	Missense	proximal	-1	no	6.880	6.355	EPSD	ICGC	4.810	Down-regulation
CAMK_CAMK2_CAMK2A_ST	Q01970	PLCB3	Q9UQM7	CAMK2A	S26	T21N	21	Missense	distal	-5	no	6.880	6.946	EPSD	ICGC;COSMIC	4.810	Up-regulation
CAMK_CAMK2_CAMK2A_ST	Q01970	PLCB3	Q9UQM7	CAMK2A	S148	A147P	147	Missense	proximal	-1	no	5.158	4.917	EPSD	ICGC;COSMIC	4.810	Down-regulation
CAMK_CAMK2_CAMK2A_ST	Q01970	PLCB3	Q9UQM7	CAMK2A	S480	G482R	482	Missense	proximal	2	no	4.514	4.933	EPSD	ICGC;COSMIC	4.810	Gain
CAMK_CAMK2_CAMK2A_ST	Q01970	PLCB3	Q9UQM7	CAMK2A	S497	T501I	501	Missense	distal	4	no	4.833	4.661	EPSD	ICGC	4.810	Loss
CAMK_CAMK2_CAMK2A_ST	Q01970	PLCB3	Q9UQM7	CAMK2A	S497	S498P	498	Missense	proximal	1	no	4.833	4.466	EPSD	ICGC;COSMIC	4.810	Loss
CAMK_CAMK2_CAMK2A_ST	Q01970	PLCB3	Q9UQM7	CAMK2A	S512	D514G	514	Missense	proximal	2	no	5.940	4.105	EPSD	ICGC;COSMIC	4.810	Loss
CAMK_CAMK2_CAMK2A_ST	Q01970	PLCB3	Q9UQM7	CAMK2A	S867	R872G	872	Missense	distal	5	no	4.864	4.821	EPSD	ICGC;COSMIC	4.810	Down-regulation
CAMK_CAMK2_CAMK2A_ST	Q01970	PLCB3	Q9UQM7	CAMK2A	S867	M869I	869	Missense	proximal	2	no	4.864	4.695	EPSD	ICGC;COSMIC	4.810	Loss
CAMK_CAMK2_CAMK2A_ST	Q01970	PLCB3	Q9UQM7	CAMK2A	S1225	T1232K	1232	Missense	distal	7	no	5.479	5.451	EPSD	ICGC;COSMIC	4.810	Down-regulation
CAMK_CAMK2_CAMK2A_ST	Q01970	PLCB3	Q9UQM7	CAMK2A	S1227	T1232K	1232	Missense	distal	5	no	5.060	5.188	EPSD	ICGC;COSMIC	4.810	Up-regulation
CAMK_CAMK2_CAMK2A_ST	P16070	CD44	Q9UQM7	CAMK2A	S184	T189A	189	Missense	distal	5	no	4.795	5.007	EPSD	ICGC	4.810	Gain
CAMK_CAMK2_CAMK2A_ST	P16070	CD44	Q9UQM7	CAMK2A	S420	K417R	417	Missense	distal	-3	no	5.968	8.236	EPSD	ICGC;COSMIC	4.810	Up-regulation
CAMK_CAMK2_CAMK2A_ST	P16070	CD44	Q9UQM7	CAMK2A	S420	R413H	413	Missense	distal	-7	no	5.968	5.908	EPSD	ICGC	4.810	Down-regulation
CAMK_CAMK2_CAMK2A_ST	Q14674	ESPL1	Q9UQM7	CAMK2A	S1433	K1435M	1435	Missense	proximal	2	no	5.412	6.628	EPSD	ICGC	4.810	Up-regulation
CAMK_CAMK2_CAMK2A_ST	Q14674	ESPL1	Q9UQM7	CAMK2A	S1455	R1456Q	1456	Missense	proximal	1	no	5.460	5.433	EPSD	ICGC;COSMIC;CCLE	4.810	Down-regulation
CAMK_CAMK2_CAMK2A_ST	Q14674	ESPL1	Q9UQM7	CAMK2A	S1455	G1453C	1453	Missense	proximal	-2	no	5.460	4.887	EPSD	ICGC	4.810	Down-regulation
CAMK_CAMK2_CAMK2A_ST	Q14674	ESPL1	Q9UQM7	CAMK2A	S1455	S1455N	1455	Missense	central	0	yes	5.460	0.000	EPSD	ICGC;COSMIC	4.810	Loss
CAMK_CAMK2_CAMK2A_ST	Q14674	ESPL1	Q9UQM7	CAMK2A	S1513	G1510R	1510	Missense	distal	-3	no	3.822	8.420	EPSD	ICGC;COSMIC	4.810	Gain
CAMK_CAMK2_CAMK2A_ST	Q14674	ESPL1	Q9UQM7	CAMK2A	S1538	K1541Q	1541	Missense	distal	3	no	5.686	5.642	EPSD	ICGC;COSMIC	4.810	Down-regulation
CAMK_CAMK2_CAMK2A_ST	Q14674	ESPL1	Q9UQM7	CAMK2A	S1538	R1535S	1535	Missense	distal	-3	no	5.686	1.225	EPSD	ICGC	4.810	Loss
CAMK_CAMK2_CAMK2A_ST	Q14674	ESPL1	Q9UQM7	CAMK2A	S1538	S1539I	1539	Missense	proximal	1	no	5.686	6.028	EPSD	ICGC	4.810	Up-regulation
CAMK_CAMK2_CAMK2A_ST	Q14674	ESPL1	Q9UQM7	CAMK2A	S1538	D1537Y	1537	Missense	proximal	-1	no	5.686	5.729	EPSD	ICGC	4.810	Up-regulation
CAMK_CAMK2_CAMK2A_ST	Q14674	ESPL1	Q9UQM7	CAMK2A	S1538	S1538F	1538	Missense	central	0	yes	5.686	0.000	EPSD	ICGC	4.810	Loss
CAMK_CAMK2_CAMK2A_ST	Q14674	ESPL1	Q9UQM7	CAMK2A	S1820	G1814C	1814	Missense	distal	-6	no	5.228	5.285	EPSD	ICGC;COSMIC	4.810	Up-regulation
CAMK_CAMK2_CAMK2A_ST	Q14674	ESPL1	Q9UQM7	CAMK2A	S1820	P1815T	1815	Missense	distal	-5	no	5.228	5.223	EPSD	ICGC	4.810	Down-regulation
CAMK_CAMK2_CAMK2A_ST	Q14674	ESPL1	Q9UQM7	CAMK2A	S1820	R1821H	1821	Missense	proximal	1	no	5.228	5.741	EPSD	ICGC;COSMIC;CCLE	4.810	Up-regulation
CAMK_CAMK2_CAMK2A_ST	Q14674	ESPL1	Q9UQM7	CAMK2A	S1820	S1820Y	1820	Missense	central	0	yes	5.228	0.000	EPSD	ICGC;COSMIC	4.810	Loss
CAMK_CAMK2_CAMK2A_ST	Q14674	ESPL1	Q9UQM7	CAMK2A	S1820	Q1823H	1823	Missense	distal	3	no	5.228	5.259	EPSD	ICGC;COSMIC	4.810	Up-regulation
CAMK_CAMK2_CAMK2A_ST	O95180	CACNA1H	Q9UQM7	CAMK2A	S215	R212L	212	Missense	distal	-3	no	6.019	0.896	EPSD	ICGC	4.810	Loss
CAMK_CAMK2_CAMK2A_ST	O95180	CACNA1H	Q9UQM7	CAMK2A	S475	R469S	469	Missense	distal	-6	no	5.128	5.173	EPSD	ICGC;COSMIC	4.810	Up-regulation
CAMK_CAMK2_CAMK2A_ST	O95180	CACNA1H	Q9UQM7	CAMK2A	S475	R473W	473	Missense	proximal	-2	no	5.128	4.310	EPSD	ICGC;COSMIC;GDSC;CCLE	4.810	Loss
CAMK_CAMK2_CAMK2A_ST	O95180	CACNA1H	Q9UQM7	CAMK2A	S475	R473Q	473	Missense	proximal	-2	no	5.128	5.345	EPSD	ICGC;COSMIC	4.810	Up-regulation
CAMK_CAMK2_CAMK2A_ST	O95180	CACNA1H	Q9UQM7	CAMK2A	S475	A480T	480	Missense	distal	5	no	5.128	4.916	EPSD	ICGC;COSMIC	4.810	Down-regulation
CAMK_CAMK2_CAMK2A_ST	O95180	CACNA1H	Q9UQM7	CAMK2A	S475	L478I	478	Missense	distal	3	no	5.128	5.196	EPSD	ICGC	4.810	Up-regulation
CAMK_CAMK2_CAMK2A_ST	O95180	CACNA1H	Q9UQM7	CAMK2A	S484	K489N	489	Missense	distal	5	no	5.694	5.614	EPSD	ICGC;COSMIC	4.810	Down-regulation
CAMK_CAMK2_CAMK2A_ST	O95180	CACNA1H	Q9UQM7	CAMK2A	S484	A480T	480	Missense	distal	-4	no	5.694	5.404	EPSD	ICGC;COSMIC	4.810	Down-regulation
CAMK_CAMK2_CAMK2A_ST	O95180	CACNA1H	Q9UQM7	CAMK2A	S484	L478I	478	Missense	distal	-6	no	5.694	5.616	EPSD	ICGC	4.810	Down-regulation
CAMK_CAMK2_CAMK2A_ST	O95180	CACNA1H	Q9UQM7	CAMK2A	S1107	P1113L	1113	Missense	distal	6	no	7.253	7.222	EPSD	ICGC;COSMIC	4.810	Down-regulation
CAMK_CAMK2_CAMK2A_ST	O95180	CACNA1H	Q9UQM7	CAMK2A	S1108	P1113L	1113	Missense	distal	5	no	7.388	7.329	EPSD	ICGC;COSMIC	4.810	Down-regulation
CAMK_CAMK2_CAMK2A_ST	O95180	CACNA1H	Q9UQM7	CAMK2A	S1110	P1113L	1113	Missense	distal	3	no	5.115	5.075	EPSD	ICGC;COSMIC	4.810	Down-regulation
CAMK_CAMK2_CAMK2A_ST	O95180	CACNA1H	Q9UQM7	CAMK2A	S1144	A1137T	1137	Missense	distal	-7	no	8.371	8.712	EPSD	ICGC;CCLE	4.810	Up-regulation
CAMK_CAMK2_CAMK2A_ST	O95180	CACNA1H	Q9UQM7	CAMK2A	S1144	R1141Q	1141	Missense	distal	-3	no	8.371	4.800	EPSD	ICGC;COSMIC	4.810	Loss
CAMK_CAMK2_CAMK2A_ST	O95180	CACNA1H	Q9UQM7	CAMK2A	S1144	A1151V	1151	Missense	distal	7	no	8.371	8.401	EPSD	ICGC	4.810	Up-regulation
CAMK_CAMK2_CAMK2A_ST	O95180	CACNA1H	Q9UQM7	CAMK2A	S1144	S1140G	1140	Missense	distal	-4	no	8.371	8.094	EPSD	ICGC;COSMIC	4.810	Down-regulation
CAMK_CAMK2_CAMK2A_ST	O95180	CACNA1H	Q9UQM7	CAMK2A	T1175	E1170D	1170	Missense	distal	-5	no	5.004	5.168	EPSD	ICGC;COSMIC	4.810	Up-regulation
CAMK_CAMK2_CAMK2A_ST	O95180	CACNA1H	Q9UQM7	CAMK2A	T1175	G1169D	1169	Missense	distal	-6	no	5.004	4.991	EPSD	ICGC;COSMIC	4.810	Down-regulation
CAMK_CAMK2_CAMK2A_ST	O95180	CACNA1H	Q9UQM7	CAMK2A	T1175	D1177N	1177	Missense	proximal	2	no	5.004	3.993	EPSD	ICGC	4.810	Loss
CAMK_CAMK2_CAMK2A_ST	O95180	CACNA1H	Q9UQM7	CAMK2A	T1175	E1178K	1178	Missense	distal	3	no	5.004	4.839	EPSD	ICGC;COSMIC	4.810	Down-regulation
CAMK_CAMK2_CAMK2A_ST	O95180	CACNA1H	Q9UQM7	CAMK2A	T1175	G1182D	1182	Missense	distal	7	no	5.004	4.974	EPSD	ICGC;COSMIC	4.810	Down-regulation
CAMK_CAMK2_CAMK2A_ST	O95180	CACNA1H	Q9UQM7	CAMK2A	T1175	G1182S	1182	Missense	distal	7	no	5.004	4.910	EPSD	ICGC;GDSC;CCLE	4.810	Down-regulation
CAMK_CAMK2_CAMK2A_ST	O95180	CACNA1H	Q9UQM7	CAMK2A	T1175	D1176N	1176	Missense	proximal	1	no	5.004	4.891	EPSD	ICGC	4.810	Down-regulation
CAMK_CAMK2_CAMK2A_ST	O95180	CACNA1H	Q9UQM7	CAMK2A	S1198	T1191S	1191	Missense	distal	-7	no	9.663	9.560	PhosphoSitePlus	ICGC	4.810	Down-regulation
CAMK_CAMK2_CAMK2A_ST	O95180	CACNA1H	Q9UQM7	CAMK2A	S1198	E1197K	1197	Missense	proximal	-1	no	9.663	9.482	PhosphoSitePlus	ICGC;COSMIC	4.810	Down-regulation
CAMK_CAMK2_CAMK2A_ST	O95180	CACNA1H	Q9UQM7	CAMK2A	S1198	R1195W	1195	Missense	distal	-3	no	9.663	-2.357	PhosphoSitePlus	ICGC;COSMIC	4.810	Loss
CAMK_CAMK2_CAMK2A_ST	O95180	CACNA1H	Q9UQM7	CAMK2A	S1587	R1580H	1580	Missense	distal	-7	no	5.655	5.595	EPSD	ICGC;COSMIC;CCLE	4.810	Down-regulation
CAMK_CAMK2_CAMK2A_ST	O95180	CACNA1H	Q9UQM7	CAMK2A	S1587	P1590S	1590	Missense	distal	3	no	5.655	5.926	EPSD	ICGC	4.810	Up-regulation
CAMK_CAMK2_CAMK2A_ST	O95180	CACNA1H	Q9UQM7	CAMK2A	S1587	R1583T	1583	Missense	distal	-4	no	5.655	5.442	EPSD	ICGC	4.810	Down-regulation
CAMK_CAMK2_CAMK2A_ST	O95180	CACNA1H	Q9UQM7	CAMK2A	T1806	G1812E	1812	Missense	distal	6	no	5.373	5.452	EPSD	ICGC	4.810	Up-regulation
CAMK_CAMK2_CAMK2A_ST	O95180	CACNA1H	Q9UQM7	CAMK2A	S1822	R1819C	1819	Missense	distal	-3	no	9.048	3.467	EPSD	ICGC;COSMIC	4.810	Loss
CAMK_CAMK2_CAMK2A_ST	O95180	CACNA1H	Q9UQM7	CAMK2A	S1822	C1828Y	1828	Missense	distal	6	no	9.048	9.104	EPSD	ICGC	4.810	Up-regulation
CAMK_CAMK2_CAMK2A_ST	O95180	CACNA1H	Q9UQM7	CAMK2A	S1926	D1930N	1930	Missense	distal	4	no	8.009	8.036	EPSD	ICGC	4.810	Up-regulation
CAMK_CAMK2_CAMK2A_ST	O95180	CACNA1H	Q9UQM7	CAMK2A	T2073	R2077H	2077	Missense	distal	4	no	6.781	6.892	EPSD	ICGC;COSMIC	4.810	Up-regulation
CAMK_CAMK2_CAMK2A_ST	O95180	CACNA1H	Q9UQM7	CAMK2A	T2073	R2068P	2068	Missense	distal	-5	no	6.781	6.853	EPSD	ICGC	4.810	Up-regulation
CAMK_CAMK2_CAMK2A_ST	O95180	CACNA1H	Q9UQM7	CAMK2A	T2073	S2080Y	2080	Missense	distal	7	no	6.781	6.955	EPSD	ICGC;COSMIC	4.810	Up-regulation
CAMK_CAMK2_CAMK2A_ST	O95180	CACNA1H	Q9UQM7	CAMK2A	S2137	V2138M	2138	Missense	proximal	1	no	8.990	9.101	EPSD	ICGC;COSMIC	4.810	Up-regulation
CAMK_CAMK2_CAMK2A_ST	O95180	CACNA1H	Q9UQM7	CAMK2A	S2137	R2133C	2133	Missense	distal	-4	no	8.990	8.356	EPSD	ICGC;COSMIC	4.810	Down-regulation
CAMK_CAMK2_CAMK2A_ST	O95180	CACNA1H	Q9UQM7	CAMK2A	S2137	R2134K	2134	Missense	distal	-3	no	8.990	6.722	EPSD	ICGC	4.810	Down-regulation
CAMK_CAMK2_CAMK2A_ST	P78352	DLG4	Q9UQM7	CAMK2A	S73	L68S	68	Missense	distal	-5	no	6.362	6.453	PhosphoSitePlus	ICGC;COSMIC	4.810	Up-regulation
CAMK_CAMK2_CAMK2A_ST	P78352	DLG4	Q9UQM7	CAMK2A	T129	R126H	126	Missense	distal	-3	no	4.971	-0.527	EPSD	ICGC;COSMIC	4.810	Loss
CAMK_CAMK2_CAMK2A_ST	P78352	DLG4	Q9UQM7	CAMK2A	T129	A136S	136	Missense	distal	7	no	4.971	4.925	EPSD	ICGC;COSMIC	4.810	Down-regulation
CAMK_CAMK2_CAMK2A_ST	Q14457	BECN1	Q9UQM7	CAMK2A	S15	Q13R	13	Missense	proximal	-2	no	5.837	5.620	EPSD	ICGC;COSMIC	4.810	Down-regulation
CAMK_CAMK2_CAMK2A_ST	Q14457	BECN1	Q9UQM7	CAMK2A	S15	M12I	12	Missense	distal	-3	no	5.837	6.383	EPSD	ICGC;COSMIC	4.810	Up-regulation
CAMK_CAMK2_CAMK2A_ST	Q14457	BECN1	Q9UQM7	CAMK2A	S15	R20H	20	Missense	distal	5	no	5.837	5.951	EPSD	ICGC;COSMIC	4.810	Up-regulation
CAMK_CAMK2_CAMK2A_ST	Q14457	BECN1	Q9UQM7	CAMK2A	S90	P85Q	85	Missense	distal	-5	no	9.575	9.405	PhosphoSitePlus	ICGC	4.810	Down-regulation
CAMK_CAMK2_CAMK2A_ST	Q14457	BECN1	Q9UQM7	CAMK2A	S234	Q240K	240	Missense	distal	6	no	6.010	5.971	EPSD	ICGC	4.810	Down-regulation
CAMK_CAMK2_CAMK2A_ST	Q14457	BECN1	Q9UQM7	CAMK2A	S234	Q230H	230	Missense	distal	-4	no	6.010	5.992	EPSD	ICGC;COSMIC	4.810	Down-regulation
CAMK_CAMK2_CAMK2A_ST	Q14457	BECN1	Q9UQM7	CAMK2A	S295	P294H	294	Missense	proximal	-1	no	5.695	5.939	EPSD	ICGC	4.810	Up-regulation
CAMK_CAMK2_CAMK2A_ST	Q14457	BECN1	Q9UQM7	CAMK2A	S295	P297T	297	Missense	proximal	2	no	5.695	5.546	EPSD	ICGC	4.810	Down-regulation
CAMK_CAMK2_CAMK2A_ST	Q14457	BECN1	Q9UQM7	CAMK2A	S337	G334R	334	Missense	distal	-3	no	3.755	8.353	EPSD	ICGC;COSMIC	4.810	Gain
CAMK_CAMK2_CAMK2A_ST	Q14457	BECN1	Q9UQM7	CAMK2A	S412	I415M	415	Missense	distal	3	no	5.732	5.796	EPSD	ICGC	4.810	Up-regulation
CAMK_CAMK2_CAMK2A_ST	Q14457	BECN1	Q9UQM7	CAMK2A	S412	D405E	405	Missense	distal	-7	no	5.732	5.532	EPSD	ICGC	4.810	Down-regulation
CAMK_CAMK2_CAMK2A_ST	Q14457	BECN1	Q9UQM7	CAMK2A	S412	D405G	405	Missense	distal	-7	no	5.732	5.820	EPSD	ICGC;COSMIC	4.810	Up-regulation
CAMK_CAMK2_CAMK2A_ST	Q13224	GRIN2B	Q9UQM7	CAMK2A	S930	V931I	931	Missense	proximal	1	no	6.367	6.575	EPSD	ICGC;COSMIC	4.810	Up-regulation
CAMK_CAMK2_CAMK2A_ST	Q13224	GRIN2B	Q9UQM7	CAMK2A	S930	Y932N	932	Missense	proximal	2	no	6.367	8.932	EPSD	ICGC;COSMIC	4.810	Up-regulation
CAMK_CAMK2_CAMK2A_ST	Q13224	GRIN2B	Q9UQM7	CAMK2A	S930	R927W	927	Missense	distal	-3	no	6.367	-5.653	EPSD	ICGC;COSMIC;CCLE	4.810	Loss
CAMK_CAMK2_CAMK2A_ST	Q13224	GRIN2B	Q9UQM7	CAMK2A	S930	S935L	935	Missense	distal	5	no	6.367	6.078	EPSD	ICGC	4.810	Down-regulation
CAMK_CAMK2_CAMK2A_ST	Q13224	GRIN2B	Q9UQM7	CAMK2A	S1303	D1305N	1305	Missense	proximal	2	no	11.156	10.145	PhosphoSitePlus	ICGC;COSMIC	4.810	Down-regulation
CAMK_CAMK2_CAMK2A_ST	Q13224	GRIN2B	Q9UQM7	CAMK2A	S1303	R1300W	1300	Missense	distal	-3	no	11.156	-0.864	PhosphoSitePlus	ICGC;COSMIC	4.810	Loss
CAMK_CAMK2_CAMK2A_ST	Q13224	GRIN2B	Q9UQM7	CAMK2A	S1303	S1303P	1303	Missense	central	0	yes	11.156	0.000	PhosphoSitePlus	ICGC	4.810	Loss
CAMK_CAMK2_CAMK2A_ST	Q13224	GRIN2B	Q9UQM7	CAMK2A	S1323	A1316T	1316	Missense	distal	-7	no	7.497	7.838	EPSD	ICGC;COSMIC	4.810	Up-regulation
CAMK_CAMK2_CAMK2A_ST	Q13224	GRIN2B	Q9UQM7	CAMK2A	S1323	R1320S	1320	Missense	distal	-3	no	7.497	3.037	EPSD	ICGC	4.810	Loss
CAMK_CAMK2_CAMK2A_ST	Q13224	GRIN2B	Q9UQM7	CAMK2A	S1323	G1328S	1328	Missense	distal	5	no	7.497	7.681	EPSD	ICGC	4.810	Up-regulation
CAMK_CAMK2_CAMK2A_ST	Q13224	GRIN2B	Q9UQM7	CAMK2A	S1323	R1329Q	1329	Missense	distal	6	no	7.497	7.504	EPSD	ICGC;COSMIC	4.810	Up-regulation
CAMK_CAMK2_CAMK2A_ST	P42261	GRIA1	Q9UQM7	CAMK2A	S567	R574W	574	Missense	distal	7	no	4.654	4.970	PhosphoSitePlus	ICGC;COSMIC	4.810	Gain
CAMK_CAMK2_CAMK2A_ST	P42261	GRIA1	Q9UQM7	CAMK2A	S645	E651D	651	Missense	distal	6	no	8.892	8.903	EPSD	ICGC	4.810	Up-regulation
CAMK_CAMK2_CAMK2A_ST	P42261	GRIA1	Q9UQM7	CAMK2A	S645	V640M	640	Missense	distal	-5	no	8.892	8.921	EPSD	ICGC;COSMIC	4.810	Up-regulation
CAMK_CAMK2_CAMK2A_ST	P42261	GRIA1	Q9UQM7	CAMK2A	S645	E648Q	648	Missense	distal	3	no	8.892	8.684	EPSD	ICGC;COSMIC	4.810	Down-regulation
CAMK_CAMK2_CAMK2A_ST	P42261	GRIA1	Q9UQM7	CAMK2A	S645	E648D	648	Missense	distal	3	no	8.892	8.770	EPSD	ICGC;COSMIC	4.810	Down-regulation
CAMK_CAMK2_CAMK2A_ST	P42261	GRIA1	Q9UQM7	CAMK2A	S645	P646L	646	Missense	proximal	1	no	8.892	9.551	EPSD	ICGC;COSMIC	4.810	Up-regulation
CAMK_CAMK2_CAMK2A_ST	P42261	GRIA1	Q9UQM7	CAMK2A	S645	D652N	652	Missense	distal	7	no	8.892	8.874	EPSD	ICGC;COSMIC	4.810	Down-regulation
CAMK_CAMK2_CAMK2A_ST	P42261	GRIA1	Q9UQM7	CAMK2A	S645	R642K	642	Missense	distal	-3	no	8.892	6.625	EPSD	ICGC;COSMIC	4.810	Down-regulation
CAMK_CAMK2_CAMK2A_ST	P42261	GRIA1	Q9UQM7	CAMK2A	S834	R833H	833	Missense	proximal	-1	no	4.697	4.842	EPSD	ICGC;COSMIC	4.810	Gain
CAMK_CAMK2_CAMK2A_ST	P42261	GRIA1	Q9UQM7	CAMK2A	S834	R838Q	838	Missense	distal	4	no	4.697	4.866	EPSD	ICGC;COSMIC	4.810	Gain
CAMK_CAMK2_CAMK2A_ST	P42261	GRIA1	Q9UQM7	CAMK2A	S836	M839I	839	Missense	distal	3	no	7.793	7.730	EPSD	ICGC;COSMIC	4.810	Down-regulation
CAMK_CAMK2_CAMK2A_ST	P42261	GRIA1	Q9UQM7	CAMK2A	S836	R833C	833	Missense	distal	-3	no	7.793	2.213	EPSD	ICGC	4.810	Loss
CAMK_CAMK2_CAMK2A_ST	P42261	GRIA1	Q9UQM7	CAMK2A	S836	R833L	833	Missense	distal	-3	no	7.793	2.671	EPSD	ICGC;COSMIC	4.810	Loss
CAMK_CAMK2_CAMK2A_ST	P42261	GRIA1	Q9UQM7	CAMK2A	S836	C829F	829	Missense	distal	-7	no	7.793	7.718	EPSD	ICGC;COSMIC	4.810	Down-regulation
CAMK_CAMK2_CAMK2A_ST	P42261	GRIA1	Q9UQM7	CAMK2A	S836	Y830C	830	Missense	distal	-6	no	7.793	7.913	EPSD	ICGC;COSMIC	4.810	Up-regulation
CAMK_CAMK2_CAMK2A_ST	P42261	GRIA1	Q9UQM7	CAMK2A	S836	S832F	832	Missense	distal	-4	no	7.793	7.276	EPSD	ICGC;COSMIC	4.810	Down-regulation
CAMK_CAMK2_CAMK2A_ST	P42261	GRIA1	Q9UQM7	CAMK2A	S836	R833H	833	Missense	distal	-3	no	7.793	2.296	EPSD	ICGC;COSMIC	4.810	Loss
CAMK_CAMK2_CAMK2A_ST	P42261	GRIA1	Q9UQM7	CAMK2A	S836	G841D	841	Missense	distal	5	no	7.793	7.853	EPSD	ICGC;COSMIC	4.810	Up-regulation
CAMK_CAMK2_CAMK2A_ST	P42261	GRIA1	Q9UQM7	CAMK2A	S836	R838W	838	Missense	proximal	2	no	7.793	6.197	EPSD	ICGC;GDSC	4.810	Down-regulation
CAMK_CAMK2_CAMK2A_ST	P42261	GRIA1	Q9UQM7	CAMK2A	S836	R838Q	838	Missense	proximal	2	no	7.793	7.163	EPSD	ICGC;COSMIC	4.810	Down-regulation
CAMK_CAMK2_CAMK2A_ST	P42261	GRIA1	Q9UQM7	CAMK2A	S849	E852K	852	Missense	distal	3	no	5.595	5.430	EPSD	ICGC;COSMIC	4.810	Down-regulation
CAMK_CAMK2_CAMK2A_ST	P42261	GRIA1	Q9UQM7	CAMK2A	S849	R855W	855	Missense	distal	6	no	5.595	5.357	EPSD	ICGC;COSMIC	4.810	Down-regulation
CAMK_CAMK2_CAMK2A_ST	P42261	GRIA1	Q9UQM7	CAMK2A	S849	Q848K	848	Missense	proximal	-1	no	5.595	5.501	EPSD	ICGC;COSMIC	4.810	Down-regulation
CAMK_CAMK2_CAMK2A_ST	P42261	GRIA1	Q9UQM7	CAMK2A	S849	I850V	850	Missense	proximal	1	no	5.595	5.387	EPSD	ICGC;COSMIC	4.810	Down-regulation
CAMK_CAMK2_CAMK2A_ST	P42261	GRIA1	Q9UQM7	CAMK2A	T858	P860H	860	Missense	proximal	2	no	6.756	6.590	EPSD	ICGC;COSMIC	4.810	Down-regulation
CAMK_CAMK2_CAMK2A_ST	P42261	GRIA1	Q9UQM7	CAMK2A	T858	E852K	852	Missense	distal	-6	no	6.756	6.857	EPSD	ICGC;COSMIC	4.810	Up-regulation
CAMK_CAMK2_CAMK2A_ST	P42261	GRIA1	Q9UQM7	CAMK2A	T858	R855W	855	Missense	distal	-3	no	6.756	-5.264	EPSD	ICGC;COSMIC	4.810	Loss
CAMK_CAMK2_CAMK2A_ST	P42261	GRIA1	Q9UQM7	CAMK2A	T858	R861H	861	Missense	distal	3	no	6.756	6.810	EPSD	ICGC;COSMIC	4.810	Up-regulation
CAMK_CAMK2_CAMK2A_ST	P42261	GRIA1	Q9UQM7	CAMK2A	T858	P860T	860	Missense	proximal	2	no	6.756	6.607	EPSD	ICGC;COSMIC	4.810	Down-regulation
CAMK_CAMK2_CAMK2A_ST	P42261	GRIA1	Q9UQM7	CAMK2A	T858	R861C	861	Missense	distal	3	no	6.756	6.493	EPSD	ICGC;COSMIC	4.810	Down-regulation
CAMK_CAMK2_CAMK2A_ST	P42261	GRIA1	Q9UQM7	CAMK2A	T858	N862K	862	Missense	distal	4	no	6.756	6.790	EPSD	ICGC;COSMIC	4.810	Up-regulation
CAMK_CAMK2_CAMK2A_ST	P42261	GRIA1	Q9UQM7	CAMK2A	T858	S857L	857	Missense	proximal	-1	no	6.756	6.546	EPSD	ICGC;COSMIC;GDSC;CCLE	4.810	Down-regulation
CAMK_CAMK2_CAMK2A_ST	P42261	GRIA1	Q9UQM7	CAMK2A	T858	P860S	860	Missense	proximal	2	no	6.756	7.234	EPSD	ICGC;COSMIC	4.810	Up-regulation
CAMK_CAMK2_CAMK2A_ST	P37840	SNCA	Q9UQM7	CAMK2A	S9	A11D	11	Missense	proximal	2	no	5.363	7.165	EPSD	ICGC	4.810	Up-regulation
CAMK_CAMK2_CAMK2A_ST	P37840	SNCA	Q9UQM7	CAMK2A	T81	E83D	83	Missense	proximal	2	no	4.153	5.069	EPSD	ICGC;COSMIC	4.810	Gain
CAMK_CAMK2_CAMK2A_ST	P10636	MAPT	Q9UQM7	CAMK2A	S113	D116E	116	Missense	distal	3	no	4.846	4.968	EPSD	ICGC;COSMIC	4.810	Up-regulation
CAMK_CAMK2_CAMK2A_ST	P10636	MAPT	Q9UQM7	CAMK2A	T167	P160L	160	Missense	distal	-7	no	5.827	5.792	EPSD	ICGC;COSMIC	4.810	Down-regulation
CAMK_CAMK2_CAMK2A_ST	P10636	MAPT	Q9UQM7	CAMK2A	T167	R164T	164	Missense	distal	-3	no	5.827	0.770	EPSD	ICGC;COSMIC	4.810	Loss
CAMK_CAMK2_CAMK2A_ST	P10636	MAPT	Q9UQM7	CAMK2A	T167	A166T	166	Missense	proximal	-1	no	5.827	5.611	EPSD	ICGC	4.810	Down-regulation
CAMK_CAMK2_CAMK2A_ST	P10636	MAPT	Q9UQM7	CAMK2A	S171	R164T	164	Missense	distal	-7	no	5.997	6.132	EPSD	ICGC;COSMIC	4.810	Up-regulation
CAMK_CAMK2_CAMK2A_ST	P10636	MAPT	Q9UQM7	CAMK2A	S171	A166T	166	Missense	distal	-5	no	5.997	5.987	EPSD	ICGC	4.810	Down-regulation
CAMK_CAMK2_CAMK2A_ST	P10636	MAPT	Q9UQM7	CAMK2A	S214	G208C	208	Missense	distal	-6	no	8.732	8.789	EPSD	ICGC;COSMIC	4.810	Up-regulation
CAMK_CAMK2_CAMK2A_ST	P10636	MAPT	Q9UQM7	CAMK2A	S214	R211S	211	Missense	distal	-3	no	8.732	4.272	EPSD	ICGC;COSMIC	4.810	Loss
CAMK_CAMK2_CAMK2A_ST	P10636	MAPT	Q9UQM7	CAMK2A	S214	G213E	213	Missense	proximal	-1	no	8.732	9.122	EPSD	ICGC;COSMIC	4.810	Up-regulation
CAMK_CAMK2_CAMK2A_ST	P10636	MAPT	Q9UQM7	CAMK2A	S318	S318L	318	Missense	central	0	yes	6.384	0.000	EPSD	ICGC;COSMIC	4.810	Loss
CAMK_CAMK2_CAMK2A_ST	P10636	MAPT	Q9UQM7	CAMK2A	S318	E314K	314	Missense	distal	-4	no	6.384	6.336	EPSD	ICGC;COSMIC	4.810	Down-regulation
CAMK_CAMK2_CAMK2A_ST	P10636	MAPT	Q9UQM7	CAMK2A	S318	A325D	325	Missense	distal	7	no	6.384	6.403	EPSD	ICGC	4.810	Up-regulation
CAMK_CAMK2_CAMK2A_ST	P10636	MAPT	Q9UQM7	CAMK2A	S341	T346I	346	Missense	distal	5	no	7.485	7.377	EPSD	ICGC;COSMIC	4.810	Down-regulation
CAMK_CAMK2_CAMK2A_ST	P10636	MAPT	Q9UQM7	CAMK2A	S341	A337V	337	Missense	distal	-4	no	7.485	7.196	EPSD	ICGC	4.810	Down-regulation
CAMK_CAMK2_CAMK2A_ST	P10636	MAPT	Q9UQM7	CAMK2A	S341	D345E	345	Missense	distal	4	no	7.485	7.722	EPSD	ICGC;COSMIC	4.810	Up-regulation
CAMK_CAMK2_CAMK2A_ST	P10636	MAPT	Q9UQM7	CAMK2A	S369	R364W	364	Missense	distal	-5	no	5.352	5.500	EPSD	ICGC;COSMIC	4.810	Up-regulation
CAMK_CAMK2_CAMK2A_ST	P10636	MAPT	Q9UQM7	CAMK2A	S369	P363L	363	Missense	distal	-6	no	5.352	5.358	EPSD	ICGC	4.810	Up-regulation
CAMK_CAMK2_CAMK2A_ST	P26678	PLN	Q9UQM7	CAMK2A	S16	R9L	9	Missense	distal	-7	no	9.816	9.943	EPSD	ICGC	4.810	Up-regulation
CAMK_CAMK2_CAMK2A_ST	P26678	PLN	Q9UQM7	CAMK2A	S16	R9S	9	Missense	distal	-7	no	9.816	9.848	EPSD	ICGC;COSMIC	4.810	Up-regulation
CAMK_CAMK2_CAMK2A_ST	P26678	PLN	Q9UQM7	CAMK2A	S16	A11V	11	Missense	distal	-5	no	9.816	9.694	EPSD	ICGC;COSMIC	4.810	Down-regulation
CAMK_CAMK2_CAMK2A_ST	P26678	PLN	Q9UQM7	CAMK2A	T17	A11V	11	Missense	distal	-6	no	9.546	9.701	PhosphoSitePlus	ICGC;COSMIC	4.810	Up-regulation
Other_Aur_AURKA_ST	Q14194	CRMP1	O14965	AURKA	T101	L97P	97	Missense	distal	-4	no	43.523	42.372	PhosphoSitePlus;EPSD	ICGC;COSMIC	39.062	Down-regulation
Other_Aur_AURKA_ST	Q14194	CRMP1	O14965	AURKA	T101	L97V	97	Missense	distal	-4	no	43.523	45.002	PhosphoSitePlus;EPSD	ICGC;COSMIC	39.062	Up-regulation
Other_Aur_AURKA_ST	Q14194	CRMP1	O14965	AURKA	T101	A96T	96	Missense	distal	-5	no	43.523	43.562	PhosphoSitePlus;EPSD	ICGC	39.062	Up-regulation
Other_Aur_AURKA_ST	Q14194	CRMP1	O14965	AURKA	T101	T102M	102	Missense	proximal	1	no	43.523	45.014	PhosphoSitePlus;EPSD	ICGC;COSMIC	39.062	Up-regulation
Other_Aur_AURKA_ST	Q14194	CRMP1	O14965	AURKA	T101	A95E	95	Missense	distal	-6	no	43.523	40.170	PhosphoSitePlus;EPSD	ICGC;COSMIC	39.062	Down-regulation
Other_Aur_AURKA_ST	Q14194	CRMP1	O14965	AURKA	T101	H107N	107	Missense	distal	6	no	43.523	43.280	PhosphoSitePlus;EPSD	ICGC	39.062	Down-regulation
Other_Aur_AURKA_ST	Q14194	CRMP1	O14965	AURKA	T101	G100A	100	Missense	proximal	-1	no	43.523	43.576	PhosphoSitePlus;EPSD	ICGC;COSMIC	39.062	Up-regulation
Other_Aur_AURKA_ST	Q14194	CRMP1	O14965	AURKA	T101	G99S	99	Missense	proximal	-2	no	43.523	40.509	PhosphoSitePlus;EPSD	ICGC	39.062	Down-regulation
Other_Aur_AURKA_ST	Q14194	CRMP1	O14965	AURKA	T101	A95V	95	Missense	distal	-6	no	43.523	42.687	PhosphoSitePlus;EPSD	ICGC;COSMIC	39.062	Down-regulation
Other_Aur_AURKA_ST	Q14194	CRMP1	O14965	AURKA	T101	H107Y	107	Missense	distal	6	no	43.523	43.468	PhosphoSitePlus;EPSD	ICGC	39.062	Down-regulation
Other_Aur_AURKA_ST	Q14194	CRMP1	O14965	AURKA	T101	V98L	98	Missense	distal	-3	no	43.523	41.169	PhosphoSitePlus;EPSD	ICGC;COSMIC	39.062	Down-regulation
Other_Aur_AURKA_ST	Q14194	CRMP1	O14965	AURKA	T101	M103T	103	Missense	proximal	2	no	43.523	41.123	PhosphoSitePlus;EPSD	ICGC;COSMIC	39.062	Down-regulation
Other_Aur_AURKA_ST	Q14194	CRMP1	O14965	AURKA	T102	L97P	97	Missense	distal	-5	no	50.086	50.073	EPSD;PhosphoSitePlus	ICGC;COSMIC	39.062	Down-regulation
Other_Aur_AURKA_ST	Q14194	CRMP1	O14965	AURKA	T102	L97V	97	Missense	distal	-5	no	50.086	50.090	EPSD;PhosphoSitePlus	ICGC;COSMIC	39.062	Up-regulation
Other_Aur_AURKA_ST	Q14194	CRMP1	O14965	AURKA	T102	A96T	96	Missense	distal	-6	no	50.086	49.865	EPSD;PhosphoSitePlus	ICGC	39.062	Down-regulation
Other_Aur_AURKA_ST	Q14194	CRMP1	O14965	AURKA	T102	T102M	102	Missense	central	0	yes	50.086	0.000	EPSD;PhosphoSitePlus	ICGC;COSMIC	39.062	Loss
Other_Aur_AURKA_ST	Q14194	CRMP1	O14965	AURKA	T102	A95E	95	Missense	distal	-7	no	50.086	49.191	EPSD;PhosphoSitePlus	ICGC;COSMIC	39.062	Down-regulation
Other_Aur_AURKA_ST	Q14194	CRMP1	O14965	AURKA	T102	H107N	107	Missense	distal	5	no	50.086	50.341	EPSD;PhosphoSitePlus	ICGC	39.062	Up-regulation
Other_Aur_AURKA_ST	Q14194	CRMP1	O14965	AURKA	T102	G100A	100	Missense	proximal	-2	no	50.086	48.592	EPSD;PhosphoSitePlus	ICGC;COSMIC	39.062	Down-regulation
Other_Aur_AURKA_ST	Q14194	CRMP1	O14965	AURKA	T102	G99S	99	Missense	distal	-3	no	50.086	48.800	EPSD;PhosphoSitePlus	ICGC	39.062	Down-regulation
Other_Aur_AURKA_ST	Q14194	CRMP1	O14965	AURKA	T102	A95V	95	Missense	distal	-7	no	50.086	50.218	EPSD;PhosphoSitePlus	ICGC;COSMIC	39.062	Up-regulation
Other_Aur_AURKA_ST	Q14194	CRMP1	O14965	AURKA	T102	H107Y	107	Missense	distal	5	no	50.086	50.783	EPSD;PhosphoSitePlus	ICGC	39.062	Up-regulation
Other_Aur_AURKA_ST	Q14194	CRMP1	O14965	AURKA	T102	V98L	98	Missense	distal	-4	no	50.086	48.607	EPSD;PhosphoSitePlus	ICGC;COSMIC	39.062	Down-regulation
Other_Aur_AURKA_ST	Q14194	CRMP1	O14965	AURKA	T102	M103T	103	Missense	proximal	1	no	50.086	48.595	EPSD;PhosphoSitePlus	ICGC;COSMIC	39.062	Down-regulation
Other_Aur_AURKA_ST	Q14194	CRMP1	O14965	AURKA	T253	V250M	250	Missense	distal	-3	no	39.325	31.589	EPSD	ICGC;COSMIC	39.062	Loss
Other_Aur_AURKA_ST	Q14194	CRMP1	O14965	AURKA	T253	K258R	258	Missense	distal	5	no	39.325	37.638	EPSD	ICGC;COSMIC	39.062	Loss
Other_Aur_AURKA_ST	Q14194	CRMP1	O14965	AURKA	T253	S259R	259	Missense	distal	6	no	39.325	39.306	EPSD	ICGC	39.062	Down-regulation
Other_Aur_AURKA_ST	Q14194	CRMP1	O14965	AURKA	T253	N247Y	247	Missense	distal	-6	no	39.325	34.237	EPSD	ICGC;COSMIC	39.062	Loss
Other_Aur_AURKA_ST	Q14194	CRMP1	O14965	AURKA	S257	V250M	250	Missense	distal	-7	no	44.388	44.689	EPSD	ICGC;COSMIC	39.062	Up-regulation
Other_Aur_AURKA_ST	Q14194	CRMP1	O14965	AURKA	S257	D262N	262	Missense	distal	5	no	44.388	43.064	EPSD	ICGC;COSMIC	39.062	Down-regulation
Other_Aur_AURKA_ST	Q14194	CRMP1	O14965	AURKA	S257	K258R	258	Missense	proximal	1	no	44.388	43.722	EPSD	ICGC;COSMIC	39.062	Down-regulation
Other_Aur_AURKA_ST	Q14194	CRMP1	O14965	AURKA	S257	S259R	259	Missense	proximal	2	no	44.388	43.182	EPSD	ICGC	39.062	Down-regulation
Other_Aur_AURKA_ST	Q14194	CRMP1	O14965	AURKA	S257	I263V	263	Missense	distal	6	no	44.388	44.227	EPSD	ICGC;COSMIC	39.062	Down-regulation
Other_Aur_AURKA_ST	Q14194	CRMP1	O14965	AURKA	S385	A389T	389	Missense	distal	4	no	40.161	39.113	EPSD	ICGC;COSMIC	39.062	Down-regulation
Other_Aur_AURKA_ST	Q14194	CRMP1	O14965	AURKA	S385	A382T	382	Missense	distal	-3	no	40.161	38.437	EPSD	ICGC;COSMIC	39.062	Loss
Other_Aur_AURKA_ST	Q14194	CRMP1	O14965	AURKA	S385	K390T	390	Missense	distal	5	no	40.161	39.958	EPSD	ICGC;COSMIC	39.062	Down-regulation
Other_Aur_AURKA_ST	Q14194	CRMP1	O14965	AURKA	S522	P528H	528	Missense	distal	6	no	39.447	39.489	EPSD	ICGC	39.062	Up-regulation
Other_Aur_AURKA_ST	O43379	WDR62	O14965	AURKA	S33	S33P	33	Missense	central	0	yes	40.800	0.000	EPSD;PhosphoSitePlus	ICGC	39.062	Loss
Other_Aur_AURKA_ST	O43379	WDR62	O14965	AURKA	T46	C41F	41	Missense	distal	-5	no	50.978	50.857	EPSD	ICGC	39.062	Down-regulation
Other_Aur_AURKA_ST	O43379	WDR62	O14965	AURKA	T46	R43L	43	Missense	distal	-3	no	50.978	43.463	EPSD	ICGC	39.062	Down-regulation
Other_Aur_AURKA_ST	O43379	WDR62	O14965	AURKA	T46	A51T	51	Missense	distal	5	no	50.978	51.610	EPSD	ICGC	39.062	Up-regulation
Other_Aur_AURKA_ST	O43379	WDR62	O14965	AURKA	S49	R43L	43	Missense	distal	-6	no	46.700	44.139	PhosphoSitePlus;EPSD	ICGC	39.062	Down-regulation
Other_Aur_AURKA_ST	O43379	WDR62	O14965	AURKA	S49	A51T	51	Missense	proximal	2	no	46.700	45.440	PhosphoSitePlus;EPSD	ICGC	39.062	Down-regulation
Other_Aur_AURKA_ST	O43379	WDR62	O14965	AURKA	T50	R43L	43	Missense	distal	-7	no	45.222	44.836	EPSD;PhosphoSitePlus	ICGC	39.062	Down-regulation
Other_Aur_AURKA_ST	O43379	WDR62	O14965	AURKA	T50	A51T	51	Missense	proximal	1	no	45.222	43.550	EPSD;PhosphoSitePlus	ICGC	39.062	Down-regulation
Other_Aur_AURKA_ST	O43379	WDR62	O14965	AURKA	S979	S980Y	980	Missense	proximal	1	no	39.825	43.902	EPSD	ICGC;COSMIC	39.062	Up-regulation
Other_Aur_AURKA_ST	O43379	WDR62	O14965	AURKA	S980	S980Y	980	Missense	central	0	yes	42.627	0.000	EPSD	ICGC;COSMIC	39.062	Loss
Other_Aur_AURKA_ST	O43379	WDR62	O14965	AURKA	T1117	P1114S	1114	Missense	distal	-3	no	45.506	47.686	EPSD	ICGC;COSMIC	39.062	Up-regulation
Other_Aur_AURKA_ST	O43379	WDR62	O14965	AURKA	T1140	G1133R	1133	Missense	distal	-7	no	37.843	39.730	EPSD	ICGC;COSMIC	39.062	Gain
Other_Aur_AURKA_ST	O43379	WDR62	O14965	AURKA	S1208	A1215V	1215	Missense	distal	7	no	40.600	40.728	EPSD	ICGC	39.062	Up-regulation
Other_Aur_AURKA_ST	O43379	WDR62	O14965	AURKA	S1224	R1225H	1225	Missense	proximal	1	no	57.772	55.784	EPSD	ICGC;COSMIC	39.062	Down-regulation
Other_Aur_AURKA_ST	O43379	WDR62	O14965	AURKA	S1224	R1220H	1220	Missense	distal	-4	no	57.772	53.337	EPSD	ICGC;COSMIC	39.062	Down-regulation
Other_Aur_AURKA_ST	O43379	WDR62	O14965	AURKA	S1224	S1228F	1228	Missense	distal	4	no	57.772	58.255	EPSD	ICGC;COSMIC	39.062	Up-regulation
Other_Aur_AURKA_ST	O43379	WDR62	O14965	AURKA	S1224	S1228Y	1228	Missense	distal	4	no	57.772	57.524	EPSD	ICGC	39.062	Down-regulation
Other_Aur_AURKA_ST	O43379	WDR62	O14965	AURKA	S1228	R1225H	1225	Missense	distal	-3	no	47.489	41.716	EPSD	ICGC;COSMIC	39.062	Down-regulation
Other_Aur_AURKA_ST	O43379	WDR62	O14965	AURKA	S1228	S1228F	1228	Missense	central	0	yes	47.489	0.000	EPSD	ICGC;COSMIC	39.062	Loss
Other_Aur_AURKA_ST	O43379	WDR62	O14965	AURKA	S1228	S1228Y	1228	Missense	central	0	yes	47.489	0.000	EPSD	ICGC	39.062	Loss
Other_Aur_AURKA_ST	O43379	WDR62	O14965	AURKA	S1248	R1245H	1245	Missense	distal	-3	no	47.027	41.254	EPSD	ICGC;COSMIC	39.062	Down-regulation
Other_Aur_AURKA_ST	O43379	WDR62	O14965	AURKA	S1248	R1245S	1245	Missense	distal	-3	no	47.027	40.548	EPSD	ICGC;COSMIC	39.062	Down-regulation
Other_Aur_AURKA_ST	O43379	WDR62	O14965	AURKA	S1248	E1252D	1252	Missense	distal	4	no	47.027	46.775	EPSD	ICGC	39.062	Down-regulation
Other_Aur_AURKA_ST	O43379	WDR62	O14965	AURKA	S1249	R1245H	1245	Missense	distal	-4	no	41.699	37.264	EPSD	ICGC;COSMIC	39.062	Loss
Other_Aur_AURKA_ST	O43379	WDR62	O14965	AURKA	S1249	R1245S	1245	Missense	distal	-4	no	41.699	42.500	EPSD	ICGC;COSMIC	39.062	Up-regulation
Other_Aur_AURKA_ST	O43379	WDR62	O14965	AURKA	S1249	E1252D	1252	Missense	distal	3	no	41.699	42.744	EPSD	ICGC	39.062	Up-regulation
Other_Aur_AURKA_ST	O43379	WDR62	O14965	AURKA	S1255	E1252D	1252	Missense	distal	-3	no	44.098	42.972	EPSD	ICGC	39.062	Down-regulation
Other_Aur_AURKA_ST	O43379	WDR62	O14965	AURKA	S1337	R1340H	1340	Missense	distal	3	no	42.985	42.719	EPSD	ICGC;COSMIC	39.062	Down-regulation
Other_Aur_AURKA_ST	O43379	WDR62	O14965	AURKA	S1435	D1428H	1428	Missense	distal	-7	no	41.817	41.187	EPSD	ICGC;COSMIC	39.062	Down-regulation
Other_Aur_AURKA_ST	O43379	WDR62	O14965	AURKA	S1435	S1435P	1435	Missense	central	0	yes	41.817	0.000	EPSD	ICGC;COSMIC	39.062	Loss
Other_Aur_AURKA_ST	O43379	WDR62	O14965	AURKA	S1435	S1435Y	1435	Missense	central	0	yes	41.817	0.000	EPSD	ICGC;COSMIC	39.062	Loss
Other_Aur_AURKA_ST	O43379	WDR62	O14965	AURKA	S1435	R1431C	1431	Missense	distal	-4	no	41.817	38.616	EPSD	ICGC;COSMIC	39.062	Loss
Other_Aur_AURKA_ST	Q9UNN5	FAF1	O14965	AURKA	S212	S214R	214	Missense	proximal	2	no	43.863	42.657	EPSD	ICGC	39.062	Down-regulation
Other_Aur_AURKA_ST	Q9UNN5	FAF1	O14965	AURKA	S212	E219D	219	Missense	distal	7	no	43.863	43.886	EPSD	ICGC;COSMIC	39.062	Up-regulation
Other_Aur_AURKA_ST	Q9UNN5	FAF1	O14965	AURKA	T216	S214R	214	Missense	proximal	-2	no	30.286	43.444	EPSD	ICGC	39.062	Gain
Other_Aur_AURKA_ST	Q9UNN5	FAF1	O14965	AURKA	T264	R268K	268	Missense	distal	4	no	42.901	43.876	EPSD	ICGC;COSMIC	39.062	Up-regulation
Other_Aur_AURKA_ST	Q9UNN5	FAF1	O14965	AURKA	S269	R268K	268	Missense	proximal	-1	no	39.220	38.872	EPSD	ICGC;COSMIC	39.062	Loss
Other_Aur_AURKA_ST	Q9UNN5	FAF1	O14965	AURKA	S270	R268K	268	Missense	proximal	-2	no	41.982	35.479	EPSD	ICGC;COSMIC	39.062	Loss
Other_Aur_AURKA_ST	Q9UNN5	FAF1	O14965	AURKA	S289	D292N	292	Missense	distal	3	no	44.167	39.681	EPSD;PhosphoSitePlus	ICGC;COSMIC	39.062	Down-regulation
Other_Aur_AURKA_ST	Q9UNN5	FAF1	O14965	AURKA	S289	D284A	284	Missense	distal	-5	no	44.167	44.120	EPSD;PhosphoSitePlus	ICGC;COSMIC	39.062	Down-regulation
Other_Aur_AURKA_ST	Q9UNN5	FAF1	O14965	AURKA	S289	D284N	284	Missense	distal	-5	no	44.167	44.198	EPSD;PhosphoSitePlus	ICGC	39.062	Up-regulation
Other_Aur_AURKA_ST	Q9UNN5	FAF1	O14965	AURKA	S291	D298Y	298	Missense	distal	7	no	43.031	43.039	PhosphoSitePlus;EPSD	ICGC	39.062	Up-regulation
Other_Aur_AURKA_ST	Q9UNN5	FAF1	O14965	AURKA	S291	D292N	292	Missense	proximal	1	no	43.031	37.457	PhosphoSitePlus;EPSD	ICGC;COSMIC	39.062	Loss
Other_Aur_AURKA_ST	Q9UNN5	FAF1	O14965	AURKA	S291	D284A	284	Missense	distal	-7	no	43.031	43.188	PhosphoSitePlus;EPSD	ICGC;COSMIC	39.062	Up-regulation
Other_Aur_AURKA_ST	Q9UNN5	FAF1	O14965	AURKA	S291	D284N	284	Missense	distal	-7	no	43.031	42.639	PhosphoSitePlus;EPSD	ICGC	39.062	Down-regulation
Other_Aur_AURKA_ST	Q9UNN5	FAF1	O14965	AURKA	S556	R550H	550	Missense	distal	-6	no	42.981	40.812	EPSD	ICGC;COSMIC	39.062	Down-regulation
Other_Aur_AURKA_ST	Q9UNN5	FAF1	O14965	AURKA	S582	T580N	580	Missense	proximal	-2	no	32.030	40.761	EPSD	ICGC;COSMIC	39.062	Gain
Other_Aur_AURKA_ST	O14965	AURKA	O14965	AURKA	S41	P38H	38	Missense	distal	-3	no	45.936	48.822	EPSD;PhosphoSitePlus	ICGC;COSMIC	39.062	Up-regulation
Other_Aur_AURKA_ST	O14965	AURKA	O14965	AURKA	S67	P70L	70	Missense	distal	3	no	44.094	43.631	PhosphoSitePlus;EPSD	ICGC;COSMIC;CCLE	39.062	Down-regulation
Other_Aur_AURKA_ST	O14965	AURKA	O14965	AURKA	S83	Q76K	76	Missense	distal	-7	no	43.988	43.571	EPSD;PhosphoSitePlus	ICGC	39.062	Down-regulation
Other_Aur_AURKA_ST	O14965	AURKA	O14965	AURKA	S98	S98N	98	Missense	central	0	yes	45.902	0.000	EPSD;PhosphoSitePlus	ICGC;COSMIC	39.062	Loss
Other_Aur_AURKA_ST	O14965	AURKA	O14965	AURKA	S98	S104L	104	Missense	distal	6	no	45.902	45.839	EPSD;PhosphoSitePlus	ICGC;COSMIC	39.062	Down-regulation
Other_Aur_AURKA_ST	O14965	AURKA	O14965	AURKA	S104	S98N	98	Missense	distal	-6	no	48.023	51.228	EPSD;PhosphoSitePlus	ICGC;COSMIC	39.062	Up-regulation
Other_Aur_AURKA_ST	O14965	AURKA	O14965	AURKA	S104	S104L	104	Missense	central	0	yes	48.023	0.000	EPSD;PhosphoSitePlus	ICGC;COSMIC	39.062	Loss
Other_Aur_AURKA_ST	O14965	AURKA	O14965	AURKA	S104	N109D	109	Missense	distal	5	no	48.023	49.346	EPSD;PhosphoSitePlus	ICGC	39.062	Up-regulation
Other_Aur_AURKA_ST	O14965	AURKA	O14965	AURKA	S266	G265E	265	Missense	proximal	-1	no	46.555	45.717	EPSD;PhosphoSitePlus	ICGC;COSMIC	39.062	Down-regulation
Other_Aur_AURKA_ST	O14965	AURKA	O14965	AURKA	S278	H280N	280	Missense	proximal	2	no	45.129	46.873	EPSD;PhosphoSitePlus	ICGC	39.062	Up-regulation
Other_Aur_AURKA_ST	O14965	AURKA	O14965	AURKA	S278	D274N	274	Missense	distal	-4	no	45.129	49.185	EPSD;PhosphoSitePlus	ICGC;COSMIC	39.062	Up-regulation
Other_Aur_AURKA_ST	O14965	AURKA	O14965	AURKA	T287	C290Y	290	Missense	distal	3	no	51.557	53.882	EPSD;PhosphoSitePlus	ICGC	39.062	Up-regulation
Other_Aur_AURKA_ST	O14965	AURKA	O14965	AURKA	T287	H280N	280	Missense	distal	-7	no	51.557	51.794	EPSD;PhosphoSitePlus	ICGC	39.062	Up-regulation
Other_Aur_AURKA_ST	O14965	AURKA	O14965	AURKA	T287	D294E	294	Missense	distal	7	no	51.557	51.533	EPSD;PhosphoSitePlus	ICGC;COSMIC	39.062	Down-regulation
Other_Aur_AURKA_ST	O14965	AURKA	O14965	AURKA	T288	C290Y	290	Missense	proximal	2	no	63.877	63.170	EPSD;PhosphoSitePlus	ICGC	39.062	Down-regulation
Other_Aur_AURKA_ST	O14965	AURKA	O14965	AURKA	T288	D294E	294	Missense	distal	6	no	63.877	63.667	EPSD;PhosphoSitePlus	ICGC;COSMIC	39.062	Down-regulation
Other_Aur_AURKA_ST	O14965	AURKA	O14965	AURKA	S342	I341V	341	Missense	proximal	-1	no	47.892	45.240	EPSD;PhosphoSitePlus	ICGC;COSMIC	39.062	Down-regulation
Other_Aur_AURKA_ST	O14965	AURKA	O14965	AURKA	S342	R340I	340	Missense	proximal	-2	no	47.892	28.863	EPSD;PhosphoSitePlus	ICGC	39.062	Loss
Other_Aur_AURKA_ST	O14965	AURKA	O14965	AURKA	S342	R343W	343	Missense	proximal	1	no	47.892	45.319	EPSD;PhosphoSitePlus	ICGC;COSMIC	39.062	Down-regulation
Other_Aur_AURKA_ST	O14965	AURKA	O14965	AURKA	S342	Q335K	335	Missense	distal	-7	no	47.892	47.475	EPSD;PhosphoSitePlus	ICGC;COSMIC	39.062	Down-regulation
Other_Aur_AURKA_ST	O15143	ARPC1B	O14965	AURKA	T297	N304T	304	Missense	distal	7	no	40.065	40.080	EPSD	ICGC	39.062	Up-regulation
Other_Aur_AURKA_ST	O15143	ARPC1B	O14965	AURKA	T297	E300D	300	Missense	distal	3	no	40.065	41.110	EPSD	ICGC	39.062	Up-regulation
Other_Aur_AURKA_ST	O15143	ARPC1B	O14965	AURKA	T297	A298T	298	Missense	proximal	1	no	40.065	38.393	EPSD	ICGC;COSMIC	39.062	Loss
Other_Aur_AURKA_ST	O15143	ARPC1B	O14965	AURKA	S336	V334E	334	Missense	proximal	-2	no	41.786	32.180	EPSD	ICGC	39.062	Loss
Other_Aur_AURKA_ST	O15143	ARPC1B	O14965	AURKA	S336	V334L	334	Missense	proximal	-2	no	41.786	43.105	EPSD	ICGC	39.062	Up-regulation
Other_Aur_AURKA_ST	O15143	ARPC1B	O14965	AURKA	S336	G338S	338	Missense	proximal	2	no	41.786	41.621	EPSD	ICGC;COSMIC	39.062	Down-regulation
Other_Aur_AURKA_ST	O15143	ARPC1B	O14965	AURKA	S336	G338C	338	Missense	proximal	2	no	41.786	43.569	EPSD	ICGC	39.062	Up-regulation
Other_Aur_AURKA_ST	O15143	ARPC1B	O14965	AURKA	S336	S333L	333	Missense	distal	-3	no	41.786	40.750	EPSD	ICGC	39.062	Down-regulation
Other_Aur_AURKA_ST	Q14980	NUMA1	O14965	AURKA	S83	P78Q	78	Missense	distal	-5	no	44.362	44.377	EPSD	ICGC	39.062	Up-regulation
Other_Aur_AURKA_ST	Q14980	NUMA1	O14965	AURKA	S83	E89K	89	Missense	distal	6	no	44.362	44.196	EPSD	ICGC	39.062	Down-regulation
Other_Aur_AURKA_ST	Q14980	NUMA1	O14965	AURKA	T163	P165T	165	Missense	proximal	2	no	44.303	42.407	EPSD	ICGC;COSMIC	39.062	Down-regulation
Other_Aur_AURKA_ST	Q14980	NUMA1	O14965	AURKA	S271	P272T	272	Missense	proximal	1	no	41.767	44.016	EPSD	ICGC;GDSC;CCLE	39.062	Up-regulation
Other_Aur_AURKA_ST	Q14980	NUMA1	O14965	AURKA	S395	Q396K	396	Missense	proximal	1	no	47.790	47.564	EPSD	ICGC	39.062	Down-regulation
Other_Aur_AURKA_ST	Q14980	NUMA1	O14965	AURKA	S633	R631Q	631	Missense	proximal	-2	no	48.213	37.573	EPSD	ICGC;COSMIC	39.062	Loss
Other_Aur_AURKA_ST	Q14980	NUMA1	O14965	AURKA	S1145	K1138M	1138	Missense	distal	-7	no	38.509	39.194	EPSD	ICGC;COSMIC	39.062	Gain
Other_Aur_AURKA_ST	Q14980	NUMA1	O14965	AURKA	S1145	R1148S	1148	Missense	distal	3	no	38.509	39.574	EPSD	ICGC	39.062	Gain
Other_Aur_AURKA_ST	Q14980	NUMA1	O14965	AURKA	S1203	H1202Q	1202	Missense	proximal	-1	no	44.554	44.623	EPSD	ICGC	39.062	Up-regulation
Other_Aur_AURKA_ST	Q14980	NUMA1	O14965	AURKA	S1203	R1196C	1196	Missense	distal	-7	no	44.554	43.347	EPSD	ICGC	39.062	Down-regulation
Other_Aur_AURKA_ST	Q96EZ8	MCRS1	O14965	AURKA	S35	A38V	38	Missense	distal	3	no	45.580	45.458	EPSD;PhosphoSitePlus	ICGC;COSMIC	39.062	Down-regulation
Other_Aur_AURKA_ST	Q96EZ8	MCRS1	O14965	AURKA	S35	T41I	41	Missense	distal	6	no	45.580	45.749	EPSD;PhosphoSitePlus	ICGC;COSMIC	39.062	Up-regulation
Other_Aur_AURKA_ST	Q96EZ8	MCRS1	O14965	AURKA	S35	L39S	39	Missense	distal	4	no	45.580	45.487	EPSD;PhosphoSitePlus	ICGC;COSMIC	39.062	Down-regulation
Other_Aur_AURKA_ST	Q96EZ8	MCRS1	O14965	AURKA	S35	R33Q	33	Missense	proximal	-2	no	45.580	34.941	EPSD;PhosphoSitePlus	ICGC;COSMIC	39.062	Loss
Other_Aur_AURKA_ST	Q96EZ8	MCRS1	O14965	AURKA	S36	A38V	38	Missense	proximal	2	no	46.092	47.524	PhosphoSitePlus;EPSD	ICGC;COSMIC	39.062	Up-regulation
Other_Aur_AURKA_ST	Q96EZ8	MCRS1	O14965	AURKA	S36	T41I	41	Missense	distal	5	no	46.092	46.602	PhosphoSitePlus;EPSD	ICGC;COSMIC	39.062	Up-regulation
Other_Aur_AURKA_ST	Q96EZ8	MCRS1	O14965	AURKA	S36	L39S	39	Missense	distal	3	no	46.092	47.207	PhosphoSitePlus;EPSD	ICGC;COSMIC	39.062	Up-regulation
Other_Aur_AURKA_ST	Q96EZ8	MCRS1	O14965	AURKA	S36	R33Q	33	Missense	distal	-3	no	46.092	36.428	PhosphoSitePlus;EPSD	ICGC;COSMIC	39.062	Loss
Other_Aur_AURKA_ST	Q96EZ8	MCRS1	O14965	AURKA	S48	T41I	41	Missense	distal	-7	no	39.106	39.156	EPSD	ICGC;COSMIC	39.062	Up-regulation
Other_Aur_AURKA_ST	Q96EZ8	MCRS1	O14965	AURKA	S48	S47R	47	Missense	proximal	-1	no	39.106	39.095	EPSD	ICGC	39.062	Down-regulation
Other_Aur_AURKA_ST	Q96EZ8	MCRS1	O14965	AURKA	S49	S47R	47	Missense	proximal	-2	no	36.068	49.226	EPSD	ICGC	39.062	Gain
Other_Aur_AURKA_ST	Q96EZ8	MCRS1	O14965	AURKA	S85	P81S	81	Missense	distal	-4	no	38.823	40.740	EPSD	ICGC;COSMIC	39.062	Gain
Other_Aur_AURKA_ST	Q96EZ8	MCRS1	O14965	AURKA	S102	P101T	101	Missense	proximal	-1	no	38.382	40.298	EPSD	ICGC;COSMIC	39.062	Gain
Other_Aur_AURKA_ST	Q96EZ8	MCRS1	O14965	AURKA	T167	E173Q	173	Missense	distal	6	no	45.075	45.074	EPSD	ICGC;COSMIC	39.062	Down-regulation
Other_Aur_AURKA_ST	Q96EZ8	MCRS1	O14965	AURKA	T167	R169W	169	Missense	proximal	2	no	45.075	44.865	EPSD	ICGC;COSMIC	39.062	Down-regulation
Other_Aur_AURKA_ST	Q96EZ8	MCRS1	O14965	AURKA	T167	T167N	167	Missense	central	0	yes	45.075	0.000	EPSD	ICGC	39.062	Loss
Other_Aur_AURKA_ST	Q96EZ8	MCRS1	O14965	AURKA	T167	R165C	165	Missense	proximal	-2	no	45.075	29.778	EPSD	ICGC;CCLE	39.062	Loss
Other_Aur_AURKA_ST	Q96EZ8	MCRS1	O14965	AURKA	S218	S224C	224	Missense	distal	6	no	39.919	39.730	EPSD	ICGC;COSMIC	39.062	Down-regulation
Other_Aur_AURKA_ST	Q96EZ8	MCRS1	O14965	AURKA	S218	S222L	222	Missense	distal	4	no	39.919	40.013	EPSD	ICGC;COSMIC	39.062	Up-regulation
Other_Aur_AURKA_ST	Q96R06	SPAG5	O14965	AURKA	S183	G179A	179	Missense	distal	-4	no	42.865	41.024	EPSD	ICGC	39.062	Down-regulation
Other_Aur_AURKA_ST	Q96R06	SPAG5	O14965	AURKA	S217	E212D	212	Missense	distal	-5	no	45.045	45.064	EPSD	ICGC;COSMIC	39.062	Up-regulation
Other_Aur_AURKA_ST	Q96R06	SPAG5	O14965	AURKA	S334	L332I	332	Missense	proximal	-2	no	39.101	29.792	EPSD	ICGC;COSMIC	39.062	Loss
Other_Aur_AURKA_ST	Q96R06	SPAG5	O14965	AURKA	S367	R370Q	370	Missense	distal	3	no	44.908	45.296	EPSD	ICGC;COSMIC	39.062	Up-regulation
Other_Aur_AURKA_ST	Q96R06	SPAG5	O14965	AURKA	S367	D371E	371	Missense	distal	4	no	44.908	45.160	EPSD	ICGC;COSMIC	39.062	Up-regulation
Other_Aur_AURKA_ST	Q96R06	SPAG5	O14965	AURKA	S367	D371N	371	Missense	distal	4	no	44.908	43.826	EPSD	ICGC	39.062	Down-regulation
Other_Aur_AURKA_ST	Q96R06	SPAG5	O14965	AURKA	S367	A372D	372	Missense	distal	5	no	44.908	46.143	EPSD	ICGC;COSMIC	39.062	Up-regulation
Other_Aur_AURKA_ST	Q96R06	SPAG5	O14965	AURKA	S401	S401C	401	Missense	central	0	yes	45.115	0.000	EPSD	ICGC	39.062	Loss
Other_Aur_AURKA_ST	Q96R06	SPAG5	O14965	AURKA	S401	T398K	398	Missense	distal	-3	no	45.115	46.905	EPSD	ICGC	39.062	Up-regulation
Other_Aur_AURKA_ST	Q96R06	SPAG5	O14965	AURKA	S401	S401F	401	Missense	central	0	yes	45.115	0.000	EPSD	ICGC	39.062	Loss
Other_Aur_AURKA_ST	Q96R06	SPAG5	O14965	AURKA	S957	M955K	955	Missense	proximal	-2	no	30.075	41.402	EPSD	ICGC	39.062	Gain
Other_Aur_AURKA_ST	Q14203	DCTN1	O14965	AURKA	S92	H85N	85	Missense	distal	-7	no	43.751	43.989	EPSD	ICGC	39.062	Up-regulation
Other_Aur_AURKA_ST	Q14203	DCTN1	O14965	AURKA	S112	K115E	115	Missense	distal	3	no	40.931	42.327	EPSD	ICGC	39.062	Up-regulation
Other_Aur_AURKA_ST	Q14203	DCTN1	O14965	AURKA	S112	S111Y	111	Missense	proximal	-1	no	40.931	39.988	EPSD	ICGC	39.062	Down-regulation
Other_Aur_AURKA_ST	Q14203	DCTN1	O14965	AURKA	T145	P150H	150	Missense	distal	5	no	39.286	39.304	EPSD	ICGC	39.062	Up-regulation
Other_Aur_AURKA_ST	Q14203	DCTN1	O14965	AURKA	T146	P150H	150	Missense	distal	4	no	57.314	57.506	EPSD	ICGC	39.062	Up-regulation
Other_Aur_AURKA_ST	Q14203	DCTN1	O14965	AURKA	S203	P199T	199	Missense	distal	-4	no	44.393	48.307	EPSD	ICGC	39.062	Up-regulation
Other_Aur_AURKA_ST	Q14203	DCTN1	O14965	AURKA	T1152	S1153I	1153	Missense	proximal	1	no	43.089	45.266	EPSD	ICGC;COSMIC	39.062	Up-regulation
Other_Aur_AURKA_ST	Q14203	DCTN1	O14965	AURKA	S1153	S1153I	1153	Missense	central	0	yes	56.697	0.000	EPSD	ICGC;COSMIC	39.062	Loss
Other_Aur_AURKA_ST	Q13761	RUNX3	O14965	AURKA	S71	E65Q	65	Missense	distal	-6	no	37.066	40.367	EPSD	ICGC;COSMIC	39.062	Gain
Other_Aur_AURKA_ST	Q13761	RUNX3	O14965	AURKA	S243	S237R	237	Missense	distal	-6	no	38.377	39.407	EPSD	ICGC;COSMIC	39.062	Gain
Other_Aur_AURKA_ST	Q13761	RUNX3	O14965	AURKA	S301	P298L	298	Missense	distal	-3	no	38.261	39.405	EPSD	ICGC;COSMIC	39.062	Gain
Other_Aur_AURKA_ST	P00352	ALDH1A1	O14965	AURKA	S207	V205M	205	Missense	proximal	-2	no	53.109	46.319	EPSD	ICGC;COSMIC	39.062	Down-regulation
Other_Aur_AURKA_ST	P46937	YAP1	O14965	AURKA	T77	A78T	78	Missense	proximal	1	no	41.891	40.219	EPSD	ICGC;COSMIC	39.062	Down-regulation
Other_Aur_AURKA_ST	P46937	YAP1	O14965	AURKA	T77	V72F	72	Missense	distal	-5	no	41.891	41.902	EPSD	ICGC	39.062	Up-regulation
Other_Aur_AURKA_ST	P46937	YAP1	O14965	AURKA	S94	P99Q	99	Missense	distal	5	no	40.709	42.598	EPSD	ICGC;COSMIC	39.062	Up-regulation
Other_Aur_AURKA_ST	P46937	YAP1	O14965	AURKA	T110	A117S	117	Missense	distal	7	no	39.541	39.594	EPSD	ICGC	39.062	Up-regulation
Other_Aur_AURKA_ST	P46937	YAP1	O14965	AURKA	T110	A115T	115	Missense	distal	5	no	39.541	40.172	EPSD	ICGC	39.062	Up-regulation
Other_Aur_AURKA_ST	P46937	YAP1	O14965	AURKA	S128	Q133L	133	Missense	distal	5	no	39.989	37.516	EPSD	ICGC;COSMIC	39.062	Loss
Other_Aur_AURKA_ST	P46937	YAP1	O14965	AURKA	S128	V123F	123	Missense	distal	-5	no	39.989	40.000	EPSD	ICGC	39.062	Up-regulation
Other_Aur_AURKA_ST	P46937	YAP1	O14965	AURKA	S128	L134F	134	Missense	distal	6	no	39.989	40.198	EPSD	ICGC;COSMIC	39.062	Up-regulation
Other_Aur_AURKA_ST	P46937	YAP1	O14965	AURKA	S128	H126R	126	Missense	proximal	-2	no	39.989	47.228	EPSD	ICGC;COSMIC	39.062	Up-regulation
Other_Aur_AURKA_ST	P46937	YAP1	O14965	AURKA	S163	D169N	169	Missense	distal	6	no	46.607	46.201	EPSD	ICGC;COSMIC	39.062	Down-regulation
Other_Aur_AURKA_ST	P46937	YAP1	O14965	AURKA	S163	S163F	163	Missense	central	0	yes	46.607	0.000	EPSD	ICGC;COSMIC	39.062	Loss
Other_Aur_AURKA_ST	P46937	YAP1	O14965	AURKA	S163	R161L	161	Missense	proximal	-2	no	46.607	36.886	EPSD	ICGC	39.062	Loss
Other_Aur_AURKA_ST	P46937	YAP1	O14965	AURKA	S163	S164F	164	Missense	proximal	1	no	46.607	53.087	EPSD	ICGC	39.062	Up-regulation
Other_Aur_AURKA_ST	P46937	YAP1	O14965	AURKA	S164	D169N	169	Missense	distal	5	no	45.881	44.558	EPSD	ICGC;COSMIC	39.062	Down-regulation
Other_Aur_AURKA_ST	P46937	YAP1	O14965	AURKA	S164	S163F	163	Missense	proximal	-1	no	45.881	46.954	EPSD	ICGC;COSMIC	39.062	Up-regulation
Other_Aur_AURKA_ST	P46937	YAP1	O14965	AURKA	S164	V171A	171	Missense	distal	7	no	45.881	45.753	EPSD	ICGC;COSMIC	39.062	Down-regulation
Other_Aur_AURKA_ST	P46937	YAP1	O14965	AURKA	S164	R161L	161	Missense	distal	-3	no	45.881	38.365	EPSD	ICGC	39.062	Loss
Other_Aur_AURKA_ST	P46937	YAP1	O14965	AURKA	S164	S164F	164	Missense	central	0	yes	45.881	0.000	EPSD	ICGC	39.062	Loss
Other_Aur_AURKA_ST	P46937	YAP1	O14965	AURKA	S274	A268P	268	Missense	distal	-6	no	51.592	50.826	EPSD	ICGC;COSMIC	39.062	Down-regulation
Other_Aur_AURKA_ST	P46937	YAP1	O14965	AURKA	S274	R272G	272	Missense	proximal	-2	no	51.592	41.448	EPSD	ICGC;COSMIC	39.062	Down-regulation
Other_Aur_AURKA_ST	P46937	YAP1	O14965	AURKA	S371	Q372R	372	Missense	proximal	1	no	40.084	39.192	EPSD	ICGC;COSMIC	39.062	Down-regulation
Other_Aur_AURKA_ST	P46937	YAP1	O14965	AURKA	S371	G369W	369	Missense	proximal	-2	no	40.084	-136.480	EPSD	ICGC;COSMIC	39.062	Loss
Other_Aur_AURKA_ST	P46937	YAP1	O14965	AURKA	S371	Q372K	372	Missense	proximal	1	no	40.084	39.858	EPSD	ICGC;COSMIC	39.062	Down-regulation
Other_Aur_AURKA_ST	P46937	YAP1	O14965	AURKA	S397	L402P	402	Missense	distal	5	no	44.220	44.804	PhosphoSitePlus	ICGC;COSMIC	39.062	Up-regulation
Other_Aur_AURKA_ST	P46937	YAP1	O14965	AURKA	S397	R394Q	394	Missense	distal	-3	no	44.220	34.556	PhosphoSitePlus	ICGC;COSMIC	39.062	Loss
Other_Aur_AURKA_ST	P46937	YAP1	O14965	AURKA	S397	S397I	397	Missense	central	0	yes	44.220	0.000	PhosphoSitePlus	ICGC	39.062	Loss
Other_Aur_AURKA_ST	P46937	YAP1	O14965	AURKA	S397	H392N	392	Missense	distal	-5	no	44.220	44.320	PhosphoSitePlus	ICGC;COSMIC	39.062	Up-regulation
Other_Aur_AURKA_ST	P46937	YAP1	O14965	AURKA	S397	T398A	398	Missense	proximal	1	no	44.220	45.892	PhosphoSitePlus	ICGC;COSMIC	39.062	Up-regulation
Other_Aur_AURKA_ST	P46937	YAP1	O14965	AURKA	S419	E422K	422	Missense	distal	3	no	40.480	39.084	EPSD	ICGC;COSMIC	39.062	Down-regulation
Other_Aur_AURKA_ST	P46937	YAP1	O14965	AURKA	S419	M423I	423	Missense	distal	4	no	40.480	40.188	EPSD	ICGC	39.062	Down-regulation
Other_Aur_AURKA_ST	Q92974	ARHGEF2	O14965	AURKA	T103	N102K	102	Missense	proximal	-1	no	39.405	40.886	EPSD	ICGC	39.062	Up-regulation
Other_Aur_AURKA_ST	Q92974	ARHGEF2	O14965	AURKA	T103	A97T	97	Missense	distal	-6	no	39.405	39.184	EPSD	ICGC	39.062	Down-regulation
Other_Aur_AURKA_ST	Q92974	ARHGEF2	O14965	AURKA	S133	R139S	139	Missense	distal	6	no	39.533	39.551	EPSD	ICGC	39.062	Up-regulation
Other_Aur_AURKA_ST	Q92974	ARHGEF2	O14965	AURKA	S142	R139S	139	Missense	distal	-3	no	47.482	41.002	EPSD	ICGC	39.062	Down-regulation
Other_Aur_AURKA_ST	Q92974	ARHGEF2	O14965	AURKA	S143	R139S	139	Missense	distal	-4	no	47.935	48.737	EPSD	ICGC	39.062	Up-regulation
Other_Aur_AURKA_ST	P38398	BRCA1	O14965	AURKA	S76	Q74K	74	Missense	proximal	-2	no	37.558	41.693	EPSD	ICGC	39.062	Gain
Other_Aur_AURKA_ST	P38398	BRCA1	O14965	AURKA	S184	T190N	190	Missense	distal	6	no	40.926	40.765	EPSD	ICGC	39.062	Down-regulation
Other_Aur_AURKA_ST	P38398	BRCA1	O14965	AURKA	T509	R507T	507	Missense	proximal	-2	no	43.947	24.733	EPSD	ICGC;COSMIC	39.062	Loss
Other_Aur_AURKA_ST	P38398	BRCA1	O14965	AURKA	S615	N609I	609	Missense	distal	-6	no	46.957	36.351	EPSD	ICGC	39.062	Loss
Other_Aur_AURKA_ST	P38398	BRCA1	O14965	AURKA	S632	N635K	635	Missense	distal	3	no	38.855	40.900	EPSD	ICGC	39.062	Gain
Other_Aur_AURKA_ST	P38398	BRCA1	O14965	AURKA	S868	S868C	868	Missense	central	0	yes	42.885	0.000	EPSD	ICGC;COSMIC	39.062	Loss
Other_Aur_AURKA_ST	P38398	BRCA1	O14965	AURKA	S1143	T1149K	1149	Missense	distal	6	no	42.911	42.781	EPSD	ICGC	39.062	Down-regulation
Other_Aur_AURKA_ST	P38398	BRCA1	O14965	AURKA	S1164	E1167D	1167	Missense	distal	3	no	40.855	41.899	EPSD	ICGC;COSMIC	39.062	Up-regulation
Other_Aur_AURKA_ST	P38398	BRCA1	O14965	AURKA	S1164	S1164F	1164	Missense	central	0	yes	40.855	0.000	EPSD	ICGC;COSMIC	39.062	Loss
Other_Aur_AURKA_ST	P38398	BRCA1	O14965	AURKA	S1164	K1160N	1160	Missense	distal	-4	no	40.855	40.498	EPSD	ICGC;COSMIC	39.062	Down-regulation
Other_Aur_AURKA_ST	P38398	BRCA1	O14965	AURKA	S1211	L1216F	1216	Missense	distal	5	no	40.404	42.361	EPSD	ICGC;COSMIC	39.062	Up-regulation
Other_Aur_AURKA_ST	P38398	BRCA1	O14965	AURKA	S1262	E1257V	1257	Missense	distal	-5	no	40.323	40.320	EPSD	ICGC;COSMIC	39.062	Down-regulation
Other_Aur_AURKA_ST	P12755	SKI	O14965	AURKA	S325	R320L	320	Missense	distal	-5	no	51.752	51.739	EPSD	ICGC	39.062	Down-regulation
Other_Aur_AURKA_ST	P12755	SKI	O14965	AURKA	S326	R320L	320	Missense	distal	-6	no	47.043	44.482	EPSD;PhosphoSitePlus	ICGC	39.062	Down-regulation
Other_Aur_AURKA_ST	P12755	SKI	O14965	AURKA	S347	S343F	343	Missense	distal	-4	no	40.452	36.403	EPSD	ICGC	39.062	Loss
Other_Aur_AURKA_ST	P12755	SKI	O14965	AURKA	S347	S354I	354	Missense	distal	7	no	40.452	40.564	EPSD	ICGC	39.062	Up-regulation
Other_Aur_AURKA_ST	P12755	SKI	O14965	AURKA	S366	G368C	368	Missense	proximal	2	no	42.403	44.186	EPSD	ICGC	39.062	Up-regulation
Other_Aur_AURKA_ST	P12755	SKI	O14965	AURKA	S383	E390K	390	Missense	distal	7	no	50.892	50.781	PhosphoSitePlus;EPSD	ICGC;COSMIC	39.062	Down-regulation
Other_Aur_AURKA_ST	P12755	SKI	O14965	AURKA	S404	P398L	398	Missense	distal	-6	no	42.731	41.750	EPSD	ICGC	39.062	Down-regulation
Other_Aur_AURKA_ST	P12755	SKI	O14965	AURKA	T458	R453L	453	Missense	distal	-5	no	42.601	42.588	EPSD	ICGC;COSMIC	39.062	Down-regulation
Other_Aur_AURKA_ST	P12755	SKI	O14965	AURKA	S498	S495F	495	Missense	distal	-3	no	41.320	35.704	EPSD	ICGC;COSMIC	39.062	Loss
Other_Aur_AURKA_ST	P12755	SKI	O14965	AURKA	S501	S495F	495	Missense	distal	-6	no	40.310	34.652	EPSD	ICGC;COSMIC	39.062	Loss
Other_Aur_AURKA_ST	P12755	SKI	O14965	AURKA	S501	S506P	506	Missense	distal	5	no	40.310	39.649	EPSD	ICGC	39.062	Down-regulation
Other_Aur_AURKA_ST	P12755	SKI	O14965	AURKA	S509	S506P	506	Missense	distal	-3	no	41.921	39.741	EPSD	ICGC	39.062	Down-regulation
Other_Aur_AURKA_ST	Q9BQG0	MYBBP1A	O14965	AURKA	S672	H676Y	676	Missense	distal	4	no	46.627	46.240	EPSD	ICGC	39.062	Down-regulation
Other_Aur_AURKA_ST	Q9BQG0	MYBBP1A	O14965	AURKA	S672	R667H	667	Missense	distal	-5	no	46.627	46.570	EPSD	ICGC	39.062	Down-regulation
Other_Aur_AURKA_ST	Q9BQG0	MYBBP1A	O14965	AURKA	S864	D870E	870	Missense	distal	6	no	41.301	41.091	EPSD	ICGC;COSMIC	39.062	Down-regulation
Other_Aur_AURKA_ST	Q9BQG0	MYBBP1A	O14965	AURKA	S983	N990D	990	Missense	distal	7	no	41.187	41.338	EPSD	ICGC;COSMIC	39.062	Up-regulation
Other_Aur_AURKA_ST	Q9BQG0	MYBBP1A	O14965	AURKA	S983	R989C	989	Missense	distal	6	no	41.187	41.016	EPSD	ICGC;COSMIC	39.062	Down-regulation
Other_Aur_AURKA_ST	Q9BQG0	MYBBP1A	O14965	AURKA	S983	Y978D	978	Missense	distal	-5	no	41.187	41.193	EPSD	ICGC;COSMIC	39.062	Up-regulation
Other_Aur_AURKA_ST	Q9BQG0	MYBBP1A	O14965	AURKA	S1166	K1172N	1172	Missense	distal	6	no	42.800	42.770	EPSD	ICGC;COSMIC	39.062	Down-regulation
Other_Aur_AURKA_ST	Q9BQG0	MYBBP1A	O14965	AURKA	S1186	R1181S	1181	Missense	distal	-5	no	42.983	42.978	EPSD	ICGC	39.062	Down-regulation
Other_Aur_AURKA_ST	Q9BQG0	MYBBP1A	O14965	AURKA	S1186	A1192V	1192	Missense	distal	6	no	42.983	42.887	EPSD	ICGC;COSMIC	39.062	Down-regulation
Other_Aur_AURKA_ST	Q9BQG0	MYBBP1A	O14965	AURKA	T1229	T1227K	1227	Missense	proximal	-2	no	32.786	45.495	EPSD	ICGC	39.062	Gain
Other_Aur_AURKA_ST	Q9BQG0	MYBBP1A	O14965	AURKA	S1248	P1245S	1245	Missense	distal	-3	no	38.094	40.274	EPSD	ICGC;COSMIC	39.062	Gain
Other_Aur_AURKA_ST	Q9BQG0	MYBBP1A	O14965	AURKA	S1259	K1257R	1257	Missense	proximal	-2	no	33.711	40.214	EPSD	ICGC;COSMIC;GDSC;CCLE	39.062	Gain
Other_Aur_AURKA_ST	Q9BQG0	MYBBP1A	O14965	AURKA	S1303	S1310I	1310	Missense	distal	7	no	51.884	51.995	PhosphoSitePlus	ICGC;COSMIC	39.062	Up-regulation
Other_Aur_AURKA_ST	Q9BQG0	MYBBP1A	O14965	AURKA	S1303	A1300S	1300	Missense	distal	-3	no	51.884	53.297	PhosphoSitePlus	ICGC;COSMIC	39.062	Up-regulation
Other_Aur_AURKA_ST	Q9BQG0	MYBBP1A	O14965	AURKA	S1303	S1303F	1303	Missense	central	0	yes	51.884	0.000	PhosphoSitePlus	ICGC;COSMIC;GDSC;CCLE	39.062	Loss
Other_Aur_AURKA_ST	P49841	GSK3B	O14965	AURKA	S215	S219Y	219	Missense	distal	4	no	40.204	39.956	EPSD	ICGC;COSMIC	39.062	Down-regulation
Other_Aur_AURKA_ST	P49841	GSK3B	O14965	AURKA	S215	P212T	212	Missense	distal	-3	no	40.204	39.247	EPSD	ICGC	39.062	Down-regulation
Other_Aur_AURKA_ST	Q9HC77	CENPJ	O14965	AURKA	S405	T402N	402	Missense	distal	-3	no	40.458	44.239	EPSD	ICGC	39.062	Up-regulation
Other_Aur_AURKA_ST	Q9HC77	CENPJ	O14965	AURKA	S405	T402A	402	Missense	distal	-3	no	40.458	42.182	EPSD	ICGC;COSMIC	39.062	Up-regulation
Other_Aur_AURKA_ST	Q9HC77	CENPJ	O14965	AURKA	S467	P470L	470	Missense	distal	3	no	46.849	46.385	PhosphoSitePlus	ICGC	39.062	Down-regulation
Other_Aur_AURKA_ST	Q9HC77	CENPJ	O14965	AURKA	S529	A533D	533	Missense	distal	4	no	43.885	44.059	EPSD	ICGC	39.062	Up-regulation
Other_Aur_AURKA_ST	Q9HC77	CENPJ	O14965	AURKA	S529	P527S	527	Missense	proximal	-2	no	43.885	45.785	EPSD	ICGC	39.062	Up-regulation
Other_Aur_AURKA_ST	Q9HC77	CENPJ	O14965	AURKA	S660	A654T	654	Missense	distal	-6	no	39.799	39.579	EPSD	ICGC;COSMIC	39.062	Down-regulation
Other_Aur_AURKA_ST	Q9HC77	CENPJ	O14965	AURKA	S660	Q657K	657	Missense	distal	-3	no	39.799	41.637	EPSD	ICGC	39.062	Up-regulation
Other_Aur_AURKA_ST	Q9HC77	CENPJ	O14965	AURKA	S660	A654V	654	Missense	distal	-6	no	39.799	38.963	EPSD	ICGC;COSMIC	39.062	Loss
Other_Aur_AURKA_ST	Q9HC77	CENPJ	O14965	AURKA	S717	P716L	716	Missense	proximal	-1	no	41.443	40.088	EPSD	ICGC	39.062	Down-regulation
Other_Aur_AURKA_ST	Q9HC77	CENPJ	O14965	AURKA	S784	S781L	781	Missense	distal	-3	no	39.720	38.684	EPSD	ICGC;COSMIC;CCLE	39.062	Loss
Other_Aur_AURKA_ST	Q9HC77	CENPJ	O14965	AURKA	S784	P780L	780	Missense	distal	-4	no	39.720	40.871	EPSD	ICGC;COSMIC	39.062	Up-regulation
Other_Aur_AURKA_ST	Q9HC77	CENPJ	O14965	AURKA	S857	D850E	850	Missense	distal	-7	no	52.074	51.337	EPSD	ICGC;COSMIC	39.062	Down-regulation
Other_Aur_AURKA_ST	Q9HC77	CENPJ	O14965	AURKA	S857	S857R	857	Missense	central	0	yes	52.074	0.000	EPSD	ICGC	39.062	Loss
Other_Aur_AURKA_ST	Q9BT25	HAUS8	O14965	AURKA	S69	S70I	70	Missense	proximal	1	no	41.742	43.919	EPSD	ICGC;COSMIC	39.062	Up-regulation
Other_Aur_AURKA_ST	Q9BT25	HAUS8	O14965	AURKA	S70	S70I	70	Missense	central	0	yes	44.480	0.000	EPSD	ICGC;COSMIC	39.062	Loss
Other_Aur_AURKA_ST	P40337	VHL	O14965	AURKA	S72	P71R	71	Missense	proximal	-1	no	46.918	47.121	PhosphoSitePlus	ICGC;COSMIC	39.062	Up-regulation
Other_Aur_AURKA_ST	P40337	VHL	O14965	AURKA	S72	V74G	74	Missense	proximal	2	no	46.918	47.535	PhosphoSitePlus	ICGC;COSMIC	39.062	Up-regulation
Other_Aur_AURKA_ST	P40337	VHL	O14965	AURKA	S72	N78I	78	Missense	distal	6	no	46.918	47.246	PhosphoSitePlus	ICGC;COSMIC	39.062	Up-regulation
Other_Aur_AURKA_ST	P40337	VHL	O14965	AURKA	S72	N78S	78	Missense	distal	6	no	46.918	47.175	PhosphoSitePlus	ICGC;COSMIC	39.062	Up-regulation
Other_Aur_AURKA_ST	P40337	VHL	O14965	AURKA	S72	S65L	65	Missense	distal	-7	no	46.918	47.105	PhosphoSitePlus	ICGC;COSMIC	39.062	Up-regulation
Other_Aur_AURKA_ST	P40337	VHL	O14965	AURKA	S72	N78K	78	Missense	distal	6	no	46.918	46.948	PhosphoSitePlus	ICGC;COSMIC;CCLE	39.062	Up-regulation
Other_Aur_AURKA_ST	P40337	VHL	O14965	AURKA	S72	S65P	65	Missense	distal	-7	no	46.918	48.778	PhosphoSitePlus	ICGC;COSMIC	39.062	Up-regulation
Other_Aur_AURKA_ST	P40337	VHL	O14965	AURKA	S72	R79P	79	Missense	distal	7	no	46.918	46.826	PhosphoSitePlus	ICGC;COSMIC	39.062	Down-regulation
Other_Aur_AURKA_ST	P40337	VHL	O14965	AURKA	S72	R79H	79	Missense	distal	7	no	46.918	46.923	PhosphoSitePlus	ICGC;COSMIC	39.062	Up-regulation
Other_Aur_AURKA_ST	P40337	VHL	O14965	AURKA	S72	V74A	74	Missense	proximal	2	no	46.918	45.485	PhosphoSitePlus	ICGC;COSMIC	39.062	Down-regulation
Other_Aur_AURKA_ST	P40337	VHL	O14965	AURKA	S111	L116I	116	Missense	distal	5	no	44.644	46.730	EPSD	ICGC	39.062	Up-regulation
Other_Aur_AURKA_ST	P40337	VHL	O14965	AURKA	S111	I109N	109	Missense	proximal	-2	no	44.644	53.191	EPSD	ICGC;COSMIC	39.062	Up-regulation
Other_Aur_AURKA_ST	P40337	VHL	O14965	AURKA	S111	Y112C	112	Missense	proximal	1	no	44.644	38.652	EPSD	ICGC;COSMIC	39.062	Loss
Other_Aur_AURKA_ST	P40337	VHL	O14965	AURKA	S111	S111R	111	Missense	central	0	yes	44.644	0.000	EPSD	ICGC;COSMIC	39.062	Loss
Other_Aur_AURKA_ST	P40337	VHL	O14965	AURKA	S111	S111G	111	Missense	central	0	yes	44.644	0.000	EPSD	ICGC;COSMIC	39.062	Loss
Other_Aur_AURKA_ST	P40337	VHL	O14965	AURKA	S111	H115Q	115	Missense	distal	4	no	44.644	44.388	EPSD	ICGC;COSMIC;CCLE	39.062	Down-regulation
Other_Aur_AURKA_ST	P40337	VHL	O14965	AURKA	S111	S111I	111	Missense	central	0	yes	44.644	0.000	EPSD	ICGC;COSMIC;CCLE	39.062	Loss
Other_Aur_AURKA_ST	P40337	VHL	O14965	AURKA	S111	W117L	117	Missense	distal	6	no	44.644	44.389	EPSD	ICGC;COSMIC	39.062	Down-regulation
Other_Aur_AURKA_ST	P40337	VHL	O14965	AURKA	S111	T105R	105	Missense	distal	-6	no	44.644	45.678	EPSD	ICGC;COSMIC	39.062	Up-regulation
Other_Aur_AURKA_ST	P40337	VHL	O14965	AURKA	S111	H115R	115	Missense	distal	4	no	44.644	43.974	EPSD	ICGC;COSMIC	39.062	Down-regulation
Other_Aur_AURKA_ST	P40337	VHL	O14965	AURKA	S111	W117G	117	Missense	distal	6	no	44.644	44.451	EPSD	ICGC;COSMIC	39.062	Down-regulation
Other_Aur_AURKA_ST	P40337	VHL	O14965	AURKA	S168	C162F	162	Missense	distal	-6	no	46.126	46.486	EPSD	ICGC;COSMIC	39.062	Up-regulation
Other_Aur_AURKA_ST	P40337	VHL	O14965	AURKA	S168	R167L	167	Missense	proximal	-1	no	46.126	44.568	EPSD	ICGC;COSMIC	39.062	Down-regulation
Other_Aur_AURKA_ST	Q8TEW0	PARD3	O14965	AURKA	S143	M136V	136	Missense	distal	-7	no	44.529	44.228	EPSD	ICGC;COSMIC	39.062	Down-regulation
Other_Aur_AURKA_ST	Q8TEW0	PARD3	O14965	AURKA	S143	P137H	137	Missense	distal	-6	no	44.529	43.940	EPSD	ICGC;COSMIC	39.062	Down-regulation
Other_Aur_AURKA_ST	Q8TEW0	PARD3	O14965	AURKA	S144	P137H	137	Missense	distal	-7	no	55.088	52.326	EPSD	ICGC;COSMIC	39.062	Down-regulation
Other_Aur_AURKA_ST	Q8TEW0	PARD3	O14965	AURKA	T401	A397T	397	Missense	distal	-4	no	39.537	44.495	EPSD	ICGC;COSMIC	39.062	Up-regulation
Other_Aur_AURKA_ST	Q8TEW0	PARD3	O14965	AURKA	S485	V480E	480	Missense	distal	-5	no	41.134	41.136	EPSD	ICGC;COSMIC	39.062	Up-regulation
Other_Aur_AURKA_ST	Q8TEW0	PARD3	O14965	AURKA	S598	S598Y	598	Missense	central	0	yes	40.677	0.000	EPSD	ICGC	39.062	Loss
Other_Aur_AURKA_ST	Q8TEW0	PARD3	O14965	AURKA	S598	S604N	604	Missense	distal	6	no	40.677	40.419	EPSD	ICGC;COSMIC	39.062	Down-regulation
Other_Aur_AURKA_ST	Q8TEW0	PARD3	O14965	AURKA	S665	T661S	661	Missense	distal	-4	no	42.295	40.298	EPSD	ICGC;COSMIC	39.062	Down-regulation
Other_Aur_AURKA_ST	Q8TEW0	PARD3	O14965	AURKA	S715	I714N	714	Missense	proximal	-1	no	46.088	42.754	EPSD	ICGC;COSMIC	39.062	Down-regulation
Other_Aur_AURKA_ST	Q8TEW0	PARD3	O14965	AURKA	S715	S715F	715	Missense	central	0	yes	46.088	0.000	EPSD	ICGC	39.062	Loss
Other_Aur_AURKA_ST	Q8TEW0	PARD3	O14965	AURKA	S715	G721W	721	Missense	distal	6	no	46.088	46.280	EPSD	ICGC;COSMIC	39.062	Up-regulation
Other_Aur_AURKA_ST	Q8TEW0	PARD3	O14965	AURKA	S715	G721V	721	Missense	distal	6	no	46.088	46.000	EPSD	ICGC;COSMIC	39.062	Down-regulation
Other_Aur_AURKA_ST	Q8TEW0	PARD3	O14965	AURKA	S715	R713K	713	Missense	proximal	-2	no	46.088	39.584	EPSD	ICGC	39.062	Down-regulation
Other_Aur_AURKA_ST	Q8TEW0	PARD3	O14965	AURKA	S720	I714N	714	Missense	distal	-6	no	30.730	41.337	EPSD	ICGC;COSMIC	39.062	Gain
Other_Aur_AURKA_ST	Q8TEW0	PARD3	O14965	AURKA	S850	K846T	846	Missense	distal	-4	no	45.306	46.396	EPSD	ICGC;COSMIC	39.062	Up-regulation
Other_Aur_AURKA_ST	Q8TEW0	PARD3	O14965	AURKA	S852	K846T	846	Missense	distal	-6	no	37.526	39.475	EPSD	ICGC;COSMIC	39.062	Gain
Other_Aur_AURKA_ST	Q8TEW0	PARD3	O14965	AURKA	S881	P880L	880	Missense	proximal	-1	no	43.757	42.402	EPSD	ICGC;COSMIC	39.062	Down-regulation
Other_Aur_AURKA_ST	Q8TEW0	PARD3	O14965	AURKA	S881	P874S	874	Missense	distal	-7	no	43.757	41.897	EPSD	ICGC;COSMIC;GDSC	39.062	Down-regulation
Other_Aur_AURKA_ST	Q8TEW0	PARD3	O14965	AURKA	S1222	R1226K	1226	Missense	distal	4	no	42.703	43.679	EPSD	ICGC	39.062	Up-regulation
Other_Aur_AURKA_ST	Q8TEW0	PARD3	O14965	AURKA	S1222	Q1215P	1215	Missense	distal	-7	no	42.703	44.512	EPSD	ICGC	39.062	Up-regulation
Other_Aur_AURKA_ST	Q8TEW0	PARD3	O14965	AURKA	S1236	S1236Y	1236	Missense	central	0	yes	41.394	0.000	EPSD	ICGC;COSMIC	39.062	Loss
Other_Aur_AURKA_ST	Q8TEW0	PARD3	O14965	AURKA	S1236	S1233F	1233	Missense	distal	-3	no	41.394	35.778	EPSD	ICGC;COSMIC	39.062	Loss
Other_Aur_AURKA_ST	Q8NHV4	NEDD1	O14965	AURKA	S89	S89F	89	Missense	central	0	yes	40.660	0.000	EPSD	ICGC;COSMIC	39.062	Loss
Other_Aur_AURKA_ST	Q8NHV4	NEDD1	O14965	AURKA	S89	G96S	96	Missense	distal	7	no	40.660	40.540	EPSD	ICGC;COSMIC	39.062	Down-regulation
Other_Aur_AURKA_ST	Q8NHV4	NEDD1	O14965	AURKA	S215	A209G	209	Missense	distal	-6	no	39.454	36.477	EPSD	ICGC	39.062	Loss
Other_Aur_AURKA_ST	Q8NHV4	NEDD1	O14965	AURKA	S215	L220F	220	Missense	distal	5	no	39.454	41.411	EPSD	ICGC	39.062	Up-regulation
Other_Aur_AURKA_ST	Q8NHV4	NEDD1	O14965	AURKA	S215	P216T	216	Missense	proximal	1	no	39.454	41.703	EPSD	ICGC;COSMIC	39.062	Up-regulation
Other_Aur_AURKA_ST	Q8NHV4	NEDD1	O14965	AURKA	T382	T380R	380	Missense	proximal	-2	no	20.913	40.127	EPSD	ICGC;COSMIC	39.062	Gain
Other_Aur_AURKA_ST	Q8NHV4	NEDD1	O14965	AURKA	S405	D400N	400	Missense	distal	-5	no	46.873	46.903	PhosphoSitePlus	ICGC;COSMIC	39.062	Up-regulation
Other_Aur_AURKA_ST	Q8NHV4	NEDD1	O14965	AURKA	S405	S404G	404	Missense	proximal	-1	no	46.873	46.932	PhosphoSitePlus	ICGC;COSMIC	39.062	Up-regulation
Other_Aur_AURKA_ST	Q8NHV4	NEDD1	O14965	AURKA	S405	M409I	409	Missense	distal	4	no	46.873	46.580	PhosphoSitePlus	ICGC	39.062	Down-regulation
Other_Aur_AURKA_ST	Q8NHV4	NEDD1	O14965	AURKA	S405	D399Y	399	Missense	distal	-6	no	46.873	47.805	PhosphoSitePlus	ICGC	39.062	Up-regulation
Other_Aur_AURKA_ST	Q8NHV4	NEDD1	O14965	AURKA	S405	G402V	402	Missense	distal	-3	no	46.873	46.904	PhosphoSitePlus	ICGC;COSMIC	39.062	Up-regulation
Other_Aur_AURKA_ST	Q8NHV4	NEDD1	O14965	AURKA	S405	G407C	407	Missense	proximal	2	no	46.873	48.655	PhosphoSitePlus	ICGC;COSMIC	39.062	Up-regulation
Other_Aur_AURKA_ST	Q8NHV4	NEDD1	O14965	AURKA	S405	F410L	410	Missense	distal	5	no	46.873	44.916	PhosphoSitePlus	ICGC;COSMIC	39.062	Down-regulation
Other_Aur_AURKA_ST	Q8NHV4	NEDD1	O14965	AURKA	S405	P412H	412	Missense	distal	7	no	46.873	46.970	PhosphoSitePlus	ICGC;COSMIC	39.062	Up-regulation
Other_Aur_AURKA_ST	Q8NHV4	NEDD1	O14965	AURKA	S455	P461S	461	Missense	distal	6	no	41.402	41.458	EPSD	ICGC	39.062	Up-regulation
Other_Aur_AURKA_ST	Q8NHV4	NEDD1	O14965	AURKA	T480	D478H	478	Missense	proximal	-2	no	41.078	42.502	EPSD	ICGC	39.062	Up-regulation
Other_Aur_AURKA_ST	Q8NHV4	NEDD1	O14965	AURKA	T522	S525A	525	Missense	distal	3	no	47.600	46.145	EPSD	ICGC;COSMIC	39.062	Down-regulation
Other_Aur_AURKA_ST	Q8NHV4	NEDD1	O14965	AURKA	T522	K527T	527	Missense	distal	5	no	47.600	47.396	EPSD	ICGC;COSMIC	39.062	Down-regulation
Other_Aur_AURKA_ST	Q8NHV4	NEDD1	O14965	AURKA	T522	S525Y	525	Missense	distal	3	no	47.600	47.587	EPSD	ICGC;COSMIC	39.062	Down-regulation
Other_Aur_AURKA_ST	Q8NHV4	NEDD1	O14965	AURKA	S558	S557F	557	Missense	proximal	-1	no	38.552	39.625	EPSD	ICGC;COSMIC	39.062	Gain
Other_Aur_AURKA_ST	Q8NHV4	NEDD1	O14965	AURKA	S558	A561S	561	Missense	distal	3	no	38.552	40.007	EPSD	ICGC	39.062	Gain
Other_Aur_AURKA_ST	Q8NHV4	NEDD1	O14965	AURKA	S565	S566L	566	Missense	proximal	1	no	34.735	40.385	EPSD	ICGC;COSMIC	39.062	Gain
Other_Aur_AURKA_ST	Q8NHV4	NEDD1	O14965	AURKA	S574	S568L	568	Missense	distal	-6	no	39.818	38.287	EPSD	ICGC;COSMIC	39.062	Loss
Other_Aur_AURKA_ST	Q8NHV4	NEDD1	O14965	AURKA	S574	R579W	579	Missense	distal	5	no	39.818	40.817	EPSD	ICGC;COSMIC	39.062	Up-regulation
Other_Aur_AURKA_ST	Q8NHV4	NEDD1	O14965	AURKA	S586	R590C	590	Missense	distal	4	no	41.236	41.211	EPSD	ICGC;COSMIC;CCLE	39.062	Down-regulation
Other_Aur_AURKA_ST	Q8NHV4	NEDD1	O14965	AURKA	S586	A582V	582	Missense	distal	-4	no	41.236	44.911	EPSD	ICGC;COSMIC	39.062	Up-regulation
Other_Aur_AURKA_ST	Q8NHV4	NEDD1	O14965	AURKA	S586	L584F	584	Missense	proximal	-2	no	41.236	32.547	EPSD	ICGC	39.062	Loss
Other_Aur_AURKA_ST	Q8NHV4	NEDD1	O14965	AURKA	S586	S586F	586	Missense	central	0	yes	41.236	0.000	EPSD	ICGC;COSMIC	39.062	Loss
Other_Aur_AURKA_ST	Q8NHV4	NEDD1	O14965	AURKA	S586	R579W	579	Missense	distal	-7	no	41.236	37.937	EPSD	ICGC;COSMIC	39.062	Loss
Other_Aur_AURKA_ST	Q8NHV4	NEDD1	O14965	AURKA	S586	R590S	590	Missense	distal	4	no	41.236	41.768	EPSD	ICGC;COSMIC	39.062	Up-regulation
Other_Aur_AURKA_ST	P53350	PLK1	O14965	AURKA	S137	E140Q	140	Missense	distal	3	no	50.188	49.801	EPSD	ICGC;COSMIC	39.062	Down-regulation
Other_Aur_AURKA_ST	P53350	PLK1	O14965	AURKA	S326	D333Y	333	Missense	distal	7	no	44.780	44.788	EPSD	ICGC	39.062	Up-regulation
Other_Aur_AURKA_ST	P53350	PLK1	O14965	AURKA	S326	I327V	327	Missense	proximal	1	no	44.780	47.343	EPSD	ICGC;COSMIC	39.062	Up-regulation
Other_Aur_AURKA_ST	P53350	PLK1	O14965	AURKA	S330	I327V	327	Missense	distal	-3	no	37.762	40.870	EPSD	ICGC;COSMIC	39.062	Gain
Other_Aur_AURKA_ST	P53350	PLK1	O14965	AURKA	S375	H373Y	373	Missense	proximal	-2	no	39.292	32.654	EPSD	ICGC	39.062	Loss
Other_Aur_AURKA_ST	P53350	PLK1	O14965	AURKA	S375	D376G	376	Missense	proximal	1	no	39.292	37.615	EPSD	ICGC	39.062	Loss
Other_Aur_AURKA_ST	P53350	PLK1	O14965	AURKA	S375	Q380K	380	Missense	distal	5	no	39.292	38.599	EPSD	ICGC;COSMIC	39.062	Loss
Other_Aur_AURKA_ST	P03372	ESR1	O14965	AURKA	S46	V51M	51	Missense	distal	5	no	39.630	38.719	EPSD	ICGC	39.062	Loss
Other_Aur_AURKA_ST	P03372	ESR1	O14965	AURKA	S46	D45E	45	Missense	proximal	-1	no	39.630	37.529	EPSD	ICGC;COSMIC	39.062	Loss
Other_Aur_AURKA_ST	P03372	ESR1	O14965	AURKA	S46	A50S	50	Missense	distal	4	no	39.630	39.597	EPSD	ICGC	39.062	Down-regulation
Other_Aur_AURKA_ST	P03372	ESR1	O14965	AURKA	S154	S154L	154	Missense	central	0	yes	44.115	0.000	EPSD	ICGC	39.062	Loss
Other_Aur_AURKA_ST	P03372	ESR1	O14965	AURKA	S154	R158H	158	Missense	distal	4	no	44.115	44.785	EPSD	ICGC;COSMIC;CCLE	39.062	Up-regulation
Other_Aur_AURKA_ST	P03372	ESR1	O14965	AURKA	S154	N153K	153	Missense	proximal	-1	no	44.115	45.596	EPSD	ICGC	39.062	Up-regulation
Other_Aur_AURKA_ST	P03372	ESR1	O14965	AURKA	S154	P147L	147	Missense	distal	-7	no	44.115	42.442	EPSD	ICGC;COSMIC	39.062	Down-regulation
Other_Aur_AURKA_ST	P03372	ESR1	O14965	AURKA	S167	E163Q	163	Missense	distal	-4	no	51.493	50.129	PhosphoSitePlus;EPSD	ICGC;COSMIC	39.062	Down-regulation
Other_Aur_AURKA_ST	P03372	ESR1	O14965	AURKA	S236	Q238R	238	Missense	proximal	2	no	39.350	37.349	EPSD	ICGC	39.062	Loss
Other_Aur_AURKA_ST	P03372	ESR1	O14965	AURKA	S236	L242I	242	Missense	distal	6	no	39.350	39.485	EPSD	ICGC	39.062	Up-regulation
Other_Aur_AURKA_ST	P03372	ESR1	O14965	AURKA	S236	R233M	233	Missense	distal	-3	no	39.350	26.452	EPSD	ICGC;COSMIC	39.062	Loss
Other_Aur_AURKA_ST	P03372	ESR1	O14965	AURKA	S305	K302T	302	Missense	distal	-3	no	43.639	41.849	EPSD;PhosphoSitePlus	ICGC;COSMIC	39.062	Down-regulation
Other_Aur_AURKA_ST	P03372	ESR1	O14965	AURKA	S305	R300L	300	Missense	distal	-5	no	43.639	43.626	EPSD;PhosphoSitePlus	ICGC;COSMIC	39.062	Down-regulation
Other_Aur_AURKA_ST	P03372	ESR1	O14965	AURKA	S305	R300S	300	Missense	distal	-5	no	43.639	43.634	EPSD;PhosphoSitePlus	ICGC;COSMIC	39.062	Down-regulation
Other_Aur_AURKA_ST	P03372	ESR1	O14965	AURKA	S305	R300H	300	Missense	distal	-5	no	43.639	43.583	EPSD;PhosphoSitePlus	ICGC;COSMIC	39.062	Down-regulation
Other_Aur_AURKA_ST	P03372	ESR1	O14965	AURKA	S559	R555L	555	Missense	distal	-4	no	46.323	46.359	EPSD	ICGC	39.062	Up-regulation
Other_Aur_AURKA_ST	P06748	NPM1	O14965	AURKA	T75	E68K	68	Missense	distal	-7	no	38.506	39.149	EPSD	ICGC;COSMIC	39.062	Gain
Other_Aur_AURKA_ST	P06748	NPM1	O14965	AURKA	S82	S88F	88	Missense	distal	6	no	43.416	43.562	EPSD	ICGC;COSMIC	39.062	Up-regulation
Other_Aur_AURKA_ST	P06748	NPM1	O14965	AURKA	S137	R142W	142	Missense	distal	5	no	39.719	40.718	EPSD	ICGC	39.062	Up-regulation
Other_Aur_AURKA_ST	P06748	NPM1	O14965	AURKA	S137	E131D	131	Missense	distal	-6	no	39.719	40.042	EPSD	ICGC;COSMIC	39.062	Up-regulation
Other_Aur_AURKA_ST	P06748	NPM1	O14965	AURKA	S143	R142W	142	Missense	proximal	-1	no	49.237	52.912	EPSD	ICGC	39.062	Up-regulation
Other_Aur_AURKA_ST	P06748	NPM1	O14965	AURKA	S243	D246Y	246	Missense	distal	3	no	45.603	44.835	EPSD	ICGC	39.062	Down-regulation
Other_Aur_AURKA_ST	P06748	NPM1	O14965	AURKA	S260	K263R	263	Missense	distal	3	no	43.470	44.090	EPSD	ICGC;COSMIC	39.062	Up-regulation
Other_Aur_AURKA_ST	P06748	NPM1	O14965	AURKA	S260	S254I	254	Missense	distal	-6	no	43.470	36.068	EPSD	ICGC	39.062	Loss
Other_Aur_AURKA_ST	Q15398	DLGAP5	O14965	AURKA	T66	G69E	69	Missense	distal	3	no	49.713	49.830	EPSD	ICGC	39.062	Up-regulation
Other_Aur_AURKA_ST	Q15398	DLGAP5	O14965	AURKA	S188	E184Q	184	Missense	distal	-4	no	40.319	38.955	EPSD	ICGC	39.062	Loss
Other_Aur_AURKA_ST	Q15398	DLGAP5	O14965	AURKA	S188	E191K	191	Missense	distal	3	no	40.319	38.923	EPSD	ICGC;COSMIC	39.062	Loss
Other_Aur_AURKA_ST	Q15398	DLGAP5	O14965	AURKA	T210	P217T	217	Missense	distal	7	no	43.258	43.304	EPSD	ICGC;COSMIC	39.062	Up-regulation
Other_Aur_AURKA_ST	Q15398	DLGAP5	O14965	AURKA	S353	V350A	350	Missense	distal	-3	no	48.549	45.819	EPSD	ICGC;COSMIC	39.062	Down-regulation
Other_Aur_AURKA_ST	Q15398	DLGAP5	O14965	AURKA	S353	E352Q	352	Missense	proximal	-1	no	48.549	48.976	EPSD	ICGC;COSMIC	39.062	Up-regulation
Other_Aur_AURKA_ST	Q15398	DLGAP5	O14965	AURKA	S624	S627Y	627	Missense	distal	3	no	42.673	42.660	EPSD	ICGC;COSMIC	39.062	Down-regulation
Other_Aur_AURKA_ST	Q15398	DLGAP5	O14965	AURKA	S627	S627Y	627	Missense	central	0	yes	47.372	0.000	PhosphoSitePlus;EPSD	ICGC;COSMIC	39.062	Loss
Other_Aur_AURKA_ST	Q15398	DLGAP5	O14965	AURKA	S630	S627Y	627	Missense	distal	-3	no	45.450	42.313	EPSD	ICGC;COSMIC	39.062	Down-regulation
Other_Aur_AURKA_ST	Q15398	DLGAP5	O14965	AURKA	S634	K641T	641	Missense	distal	7	no	40.250	40.248	EPSD	ICGC;COSMIC	39.062	Down-regulation
Other_Aur_AURKA_ST	Q15398	DLGAP5	O14965	AURKA	S634	S627Y	627	Missense	distal	-7	no	40.250	40.437	EPSD	ICGC;COSMIC	39.062	Up-regulation
Other_Aur_AURKA_ST	Q15398	DLGAP5	O14965	AURKA	S650	M654R	654	Missense	distal	4	no	42.928	41.517	EPSD	ICGC	39.062	Down-regulation
Other_Aur_AURKA_ST	Q15398	DLGAP5	O14965	AURKA	S690	A694P	694	Missense	distal	4	no	42.807	42.720	EPSD	ICGC	39.062	Down-regulation
Other_Aur_AURKA_ST	Q15398	DLGAP5	O14965	AURKA	S690	R688G	688	Missense	proximal	-2	no	42.807	32.663	EPSD	ICGC;COSMIC	39.062	Loss
Other_Aur_AURKA_ST	Q15398	DLGAP5	O14965	AURKA	S690	R688S	688	Missense	proximal	-2	no	42.807	29.648	EPSD	ICGC;COSMIC	39.062	Loss
Other_Aur_AURKA_ST	Q15398	DLGAP5	O14965	AURKA	S725	E722D	722	Missense	distal	-3	no	49.847	48.722	EPSD;PhosphoSitePlus	ICGC;COSMIC	39.062	Down-regulation
Other_Aur_AURKA_ST	Q15398	DLGAP5	O14965	AURKA	S725	S721N	721	Missense	distal	-4	no	49.847	50.398	EPSD;PhosphoSitePlus	ICGC;COSMIC	39.062	Up-regulation
Other_Aur_AURKA_ST	Q15398	DLGAP5	O14965	AURKA	S725	S720F	720	Missense	distal	-5	no	49.847	49.854	EPSD;PhosphoSitePlus	ICGC;COSMIC	39.062	Up-regulation
Other_Aur_AURKA_ST	Q15398	DLGAP5	O14965	AURKA	S725	P727H	727	Missense	proximal	2	no	49.847	48.785	EPSD;PhosphoSitePlus	ICGC;COSMIC;GDSC;CCLE	39.062	Down-regulation
Other_Aur_AURKA_ST	Q15398	DLGAP5	O14965	AURKA	S787	T784N	784	Missense	distal	-3	no	35.700	39.480	EPSD	ICGC;COSMIC	39.062	Gain
Other_Aur_AURKA_ST	Q13158	FADD	O14965	AURKA	S41	F46L	46	Missense	distal	5	no	42.277	40.320	EPSD	ICGC;GDSC;CCLE	39.062	Down-regulation
Other_Aur_AURKA_ST	Q13158	FADD	O14965	AURKA	S69	R71L	71	Missense	proximal	2	no	42.411	42.638	EPSD	ICGC;COSMIC	39.062	Up-regulation
Other_Aur_AURKA_ST	Q13158	FADD	O14965	AURKA	S69	R72L	72	Missense	distal	3	no	42.411	42.361	EPSD	ICGC;COSMIC	39.062	Down-regulation
Other_Aur_AURKA_ST	Q9NRM7	LATS2	O14965	AURKA	T45	S46T	46	Missense	proximal	1	no	36.611	39.859	EPSD	ICGC	39.062	Gain
Other_Aur_AURKA_ST	Q9NRM7	LATS2	O14965	AURKA	T45	P41T	41	Missense	distal	-4	no	36.611	40.525	EPSD	ICGC	39.062	Gain
Other_Aur_AURKA_ST	Q9NRM7	LATS2	O14965	AURKA	S83	P86T	86	Missense	distal	3	no	49.494	47.559	PhosphoSitePlus;EPSD	ICGC	39.062	Down-regulation
Other_Aur_AURKA_ST	Q9NRM7	LATS2	O14965	AURKA	S172	S179L	179	Missense	distal	7	no	62.398	62.371	EPSD	ICGC;COSMIC	39.062	Down-regulation
Other_Aur_AURKA_ST	Q9NRM7	LATS2	O14965	AURKA	S172	R169W	169	Missense	distal	-3	no	62.398	-16.774	EPSD	ICGC	39.062	Loss
Other_Aur_AURKA_ST	Q9NRM7	LATS2	O14965	AURKA	S172	P171H	171	Missense	proximal	-1	no	62.398	62.191	EPSD	ICGC	39.062	Down-regulation
Other_Aur_AURKA_ST	Q9NRM7	LATS2	O14965	AURKA	S172	T168K	168	Missense	distal	-4	no	62.398	61.308	EPSD	ICGC	39.062	Down-regulation
Other_Aur_AURKA_ST	Q9NRM7	LATS2	O14965	AURKA	S172	P166T	166	Missense	distal	-6	no	62.398	62.943	EPSD	ICGC;COSMIC	39.062	Up-regulation
Other_Aur_AURKA_ST	Q9NRM7	LATS2	O14965	AURKA	S272	R271C	271	Missense	proximal	-1	no	40.852	40.636	EPSD	ICGC	39.062	Down-regulation
Other_Aur_AURKA_ST	Q9NRM7	LATS2	O14965	AURKA	S272	V269A	269	Missense	distal	-3	no	40.852	38.122	EPSD	ICGC;COSMIC	39.062	Loss
Other_Aur_AURKA_ST	Q9NRM7	LATS2	O14965	AURKA	S274	R271C	271	Missense	distal	-3	no	51.716	47.179	EPSD	ICGC	39.062	Down-regulation
Other_Aur_AURKA_ST	Q9NRM7	LATS2	O14965	AURKA	S274	V269A	269	Missense	distal	-5	no	51.716	51.691	EPSD	ICGC;COSMIC	39.062	Down-regulation
Other_Aur_AURKA_ST	Q9NRM7	LATS2	O14965	AURKA	S288	P290S	290	Missense	proximal	2	no	38.898	40.146	EPSD	ICGC;COSMIC	39.062	Gain
Other_Aur_AURKA_ST	Q9NRM7	LATS2	O14965	AURKA	S335	S335N	335	Missense	central	0	yes	41.945	0.000	EPSD	ICGC;COSMIC	39.062	Loss
Other_Aur_AURKA_ST	Q9NRM7	LATS2	O14965	AURKA	S380	P384L	384	Missense	distal	4	no	70.275	70.422	EPSD;PhosphoSitePlus	ICGC;COSMIC;GDSC	39.062	Up-regulation
Other_Aur_AURKA_ST	Q9NRM7	LATS2	O14965	AURKA	S380	E387G	387	Missense	distal	7	no	70.275	70.346	EPSD;PhosphoSitePlus	ICGC	39.062	Up-regulation
Other_Aur_AURKA_ST	Q9NRM7	LATS2	O14965	AURKA	S576	V578I	578	Missense	proximal	2	no	45.265	44.930	EPSD	ICGC;COSMIC	39.062	Down-regulation
Other_Aur_AURKA_ST	Q9NRM7	LATS2	O14965	AURKA	S835	S835R	835	Missense	central	0	yes	49.319	0.000	EPSD	ICGC	39.062	Loss
Other_Aur_AURKA_ST	O15350	TP73	O14965	AURKA	S223	V217M	217	Missense	distal	-6	no	40.317	40.461	EPSD	ICGC;COSMIC	39.062	Up-regulation
Other_Aur_AURKA_ST	O15350	TP73	O14965	AURKA	S223	V230A	230	Missense	distal	7	no	40.317	40.190	EPSD	ICGC;COSMIC	39.062	Down-regulation
Other_Aur_AURKA_ST	O15350	TP73	O14965	AURKA	S235	V230A	230	Missense	distal	-5	no	53.827	53.802	PhosphoSitePlus	ICGC;COSMIC	39.062	Down-regulation
Other_Aur_AURKA_ST	O15350	TP73	O14965	AURKA	S235	S235R	235	Missense	central	0	yes	53.827	0.000	PhosphoSitePlus	ICGC;COSMIC	39.062	Loss
Other_Aur_AURKA_ST	O15350	TP73	O14965	AURKA	S235	G232S	232	Missense	distal	-3	no	53.827	52.542	PhosphoSitePlus	ICGC;COSMIC	39.062	Down-regulation
Other_Aur_AURKA_ST	O15350	TP73	O14965	AURKA	S235	P242L	242	Missense	distal	7	no	53.827	53.910	PhosphoSitePlus	ICGC;COSMIC	39.062	Up-regulation
Other_Aur_AURKA_ST	O15350	TP73	O14965	AURKA	S289	I294L	294	Missense	distal	5	no	54.533	52.447	EPSD	ICGC;COSMIC	39.062	Down-regulation
Other_Aur_AURKA_ST	O15350	TP73	O14965	AURKA	S471	S471R	471	Missense	central	0	yes	40.632	0.000	EPSD	ICGC;COSMIC	39.062	Loss
Other_Aur_AURKA_ST	O15350	TP73	O14965	AURKA	S471	S474F	474	Missense	distal	3	no	40.632	40.686	EPSD	ICGC	39.062	Up-regulation
Other_Aur_AURKA_ST	O14777	NDC80	O14965	AURKA	S44	N46K	46	Missense	proximal	2	no	46.151	44.108	PhosphoSitePlus;EPSD	ICGC;COSMIC	39.062	Down-regulation
Other_Aur_AURKA_ST	O14777	NDC80	O14965	AURKA	S44	K42N	42	Missense	proximal	-2	no	46.151	42.173	PhosphoSitePlus;EPSD	ICGC;COSMIC	39.062	Down-regulation
Other_Aur_AURKA_ST	O14777	NDC80	O14965	AURKA	S55	R52K	52	Missense	distal	-3	no	48.968	41.142	EPSD;PhosphoSitePlus	ICGC	39.062	Down-regulation
Other_Aur_AURKA_ST	O14777	NDC80	O14965	AURKA	S66	I73M	73	Missense	distal	7	no	40.871	40.718	EPSD	ICGC;COSMIC	39.062	Down-regulation
Other_Aur_AURKA_ST	O14777	NDC80	O14965	AURKA	S66	L71P	71	Missense	distal	5	no	40.871	41.454	EPSD	ICGC	39.062	Up-regulation
Other_Aur_AURKA_ST	O14777	NDC80	O14965	AURKA	S69	I73M	73	Missense	distal	4	no	48.764	49.056	EPSD;PhosphoSitePlus	ICGC;COSMIC	39.062	Up-regulation
Other_Aur_AURKA_ST	O14777	NDC80	O14965	AURKA	S69	L71P	71	Missense	proximal	2	no	48.764	48.495	EPSD;PhosphoSitePlus	ICGC	39.062	Down-regulation
Other_Aur_AURKA_ST	O14777	NDC80	O14965	AURKA	T485	E483D	483	Missense	proximal	-2	no	29.303	41.287	EPSD	ICGC	39.062	Gain
Other_Aur_AURKA_ST	O14777	NDC80	O14965	AURKA	S499	K497R	497	Missense	proximal	-2	no	32.796	39.300	EPSD	ICGC;COSMIC	39.062	Gain
Other_Aur_AURKA_ST	O95983	MBD3	O14965	AURKA	S85	K92N	92	Missense	distal	7	no	47.557	47.541	PhosphoSitePlus;EPSD	ICGC;COSMIC	39.062	Down-regulation
Other_Aur_AURKA_ST	Q99708	RBBP8	O14965	AURKA	T241	S243I	243	Missense	proximal	2	no	39.537	38.750	EPSD	ICGC;COSMIC	39.062	Loss
Other_Aur_AURKA_ST	Q99708	RBBP8	O14965	AURKA	T241	M235I	235	Missense	distal	-6	no	39.537	32.612	EPSD	ICGC;COSMIC	39.062	Loss
Other_Aur_AURKA_ST	Q99708	RBBP8	O14965	AURKA	S242	S243I	243	Missense	proximal	1	no	42.709	44.886	EPSD	ICGC;COSMIC	39.062	Up-regulation
Other_Aur_AURKA_ST	Q99708	RBBP8	O14965	AURKA	S242	M235I	235	Missense	distal	-7	no	42.709	41.867	EPSD	ICGC;COSMIC	39.062	Down-regulation
Other_Aur_AURKA_ST	Q99708	RBBP8	O14965	AURKA	S309	T315P	315	Missense	distal	6	no	42.085	42.125	EPSD	ICGC	39.062	Up-regulation
Other_Aur_AURKA_ST	Q99708	RBBP8	O14965	AURKA	S313	T315P	315	Missense	proximal	2	no	38.440	40.337	EPSD	ICGC	39.062	Gain
Other_Aur_AURKA_ST	Q99708	RBBP8	O14965	AURKA	T361	H358R	358	Missense	distal	-3	no	39.739	45.512	EPSD	ICGC;COSMIC	39.062	Up-regulation
Other_Aur_AURKA_ST	Q99708	RBBP8	O14965	AURKA	T361	H358Y	358	Missense	distal	-3	no	39.739	35.896	EPSD	ICGC;COSMIC	39.062	Loss
Other_Aur_AURKA_ST	Q99708	RBBP8	O14965	AURKA	T361	P363T	363	Missense	proximal	2	no	39.739	37.843	EPSD	ICGC;COSMIC	39.062	Loss
Other_Aur_AURKA_ST	Q99708	RBBP8	O14965	AURKA	T361	K355E	355	Missense	distal	-6	no	39.739	38.556	EPSD	ICGC;COSMIC	39.062	Loss
Other_Aur_AURKA_ST	Q99708	RBBP8	O14965	AURKA	S428	G425C	425	Missense	distal	-3	no	45.418	46.075	EPSD	ICGC	39.062	Up-regulation
Other_Aur_AURKA_ST	Q99708	RBBP8	O14965	AURKA	S428	E435D	435	Missense	distal	7	no	45.418	45.441	EPSD	ICGC;COSMIC	39.062	Up-regulation
Other_Aur_AURKA_ST	Q99708	RBBP8	O14965	AURKA	S439	E435D	435	Missense	distal	-4	no	44.122	39.900	EPSD	ICGC;COSMIC	39.062	Down-regulation
Other_Aur_AURKA_ST	Q99708	RBBP8	O14965	AURKA	T450	R447W	447	Missense	distal	-3	no	39.663	-39.509	EPSD	ICGC	39.062	Loss
Other_Aur_AURKA_ST	Q49MG5	MAP9	O14965	AURKA	S180	R177W	177	Missense	distal	-3	no	41.687	-37.485	EPSD	ICGC;COSMIC	39.062	Loss
Other_Aur_AURKA_ST	Q49MG5	MAP9	O14965	AURKA	S291	T296I	296	Missense	distal	5	no	42.006	42.516	EPSD	ICGC	39.062	Up-regulation
Other_Aur_AURKA_ST	Q49MG5	MAP9	O14965	AURKA	S305	S305C	305	Missense	central	0	yes	46.356	0.000	EPSD;PhosphoSitePlus	ICGC;COSMIC	39.062	Loss
Other_Aur_AURKA_ST	Q49MG5	MAP9	O14965	AURKA	S363	N360H	360	Missense	distal	-3	no	40.835	40.897	EPSD	ICGC	39.062	Up-regulation
Other_Aur_AURKA_ST	Q49MG5	MAP9	O14965	AURKA	S370	T377A	377	Missense	distal	7	no	39.850	39.861	EPSD	ICGC;COSMIC	39.062	Up-regulation
Other_Aur_AURKA_ST	Q49MG5	MAP9	O14965	AURKA	T377	T377A	377	Missense	central	0	yes	39.173	0.000	EPSD	ICGC;COSMIC	39.062	Loss
Other_Aur_AURKA_ST	Q49MG5	MAP9	O14965	AURKA	S385	R389G	389	Missense	distal	4	no	42.090	42.900	EPSD	ICGC;COSMIC	39.062	Up-regulation
Other_Aur_AURKA_ST	Q49MG5	MAP9	O14965	AURKA	S385	P391L	391	Missense	distal	6	no	42.090	42.083	EPSD	ICGC	39.062	Down-regulation
Other_Aur_AURKA_ST	Q49MG5	MAP9	O14965	AURKA	S625	R618Q	618	Missense	distal	-7	no	48.519	47.996	PhosphoSitePlus;EPSD	ICGC;COSMIC	39.062	Down-regulation
Other_Aur_AURKA_ST	Q49MG5	MAP9	O14965	AURKA	S625	E630D	630	Missense	distal	5	no	48.519	49.447	PhosphoSitePlus;EPSD	ICGC;COSMIC	39.062	Up-regulation
Other_Aur_AURKA_ST	Q49MG5	MAP9	O14965	AURKA	S625	L632I	632	Missense	distal	7	no	48.519	48.657	PhosphoSitePlus;EPSD	ICGC	39.062	Up-regulation
Other_Aur_AURKA_ST	Q49MG5	MAP9	O14965	AURKA	S625	K621N	621	Missense	distal	-4	no	48.519	48.162	PhosphoSitePlus;EPSD	ICGC	39.062	Down-regulation
Other_Aur_AURKA_ST	Q96CX2	KCTD12	O14965	AURKA	S187	P193R	193	Missense	distal	6	no	42.744	42.782	EPSD	ICGC	39.062	Up-regulation
Other_Aur_AURKA_ST	Q96CX2	KCTD12	O14965	AURKA	S187	A191V	191	Missense	distal	4	no	42.744	42.451	EPSD	ICGC;COSMIC	39.062	Down-regulation
Other_Aur_AURKA_ST	Q96CX2	KCTD12	O14965	AURKA	S200	D202E	202	Missense	proximal	2	no	47.442	46.672	EPSD;PhosphoSitePlus	ICGC;COSMIC	39.062	Down-regulation
Other_Aur_AURKA_ST	Q96CX2	KCTD12	O14965	AURKA	S200	P193R	193	Missense	distal	-7	no	47.442	46.155	EPSD;PhosphoSitePlus	ICGC	39.062	Down-regulation
Other_Aur_AURKA_ST	Q96CX2	KCTD12	O14965	AURKA	S200	R206L	206	Missense	distal	6	no	47.442	47.397	EPSD;PhosphoSitePlus	ICGC;COSMIC	39.062	Down-regulation
Other_Aur_AURKA_ST	Q96CX2	KCTD12	O14965	AURKA	S200	T196A	196	Missense	distal	-4	no	47.442	42.483	EPSD;PhosphoSitePlus	ICGC;COSMIC	39.062	Down-regulation
Other_Aur_AURKA_ST	Q96CX2	KCTD12	O14965	AURKA	S200	S204N	204	Missense	distal	4	no	47.442	46.567	EPSD;PhosphoSitePlus	ICGC	39.062	Down-regulation
Other_Aur_AURKA_ST	Q96CX2	KCTD12	O14965	AURKA	S207	D202E	202	Missense	distal	-5	no	49.538	49.519	EPSD	ICGC;COSMIC	39.062	Down-regulation
Other_Aur_AURKA_ST	Q96CX2	KCTD12	O14965	AURKA	S207	R206L	206	Missense	proximal	-1	no	49.538	47.980	EPSD	ICGC;COSMIC	39.062	Down-regulation
Other_Aur_AURKA_ST	Q96CX2	KCTD12	O14965	AURKA	S207	S204N	204	Missense	distal	-3	no	49.538	50.182	EPSD	ICGC	39.062	Up-regulation
Other_Aur_AURKA_ST	Q96CX2	KCTD12	O14965	AURKA	S217	R222Q	222	Missense	distal	5	no	40.760	43.140	EPSD	ICGC;COSMIC	39.062	Up-regulation
Other_Aur_AURKA_ST	Q96CX2	KCTD12	O14965	AURKA	S243	T242A	242	Missense	proximal	-1	no	45.095	43.505	PhosphoSitePlus;EPSD	ICGC	39.062	Down-regulation
Other_Aur_AURKA_ST	Q96CX2	KCTD12	O14965	AURKA	S243	T242M	242	Missense	proximal	-1	no	45.095	43.512	PhosphoSitePlus;EPSD	ICGC;COSMIC	39.062	Down-regulation
Other_Aur_AURKA_ST	Q96CX2	KCTD12	O14965	AURKA	S243	A245T	245	Missense	proximal	2	no	45.095	43.835	PhosphoSitePlus;EPSD	ICGC;COSMIC	39.062	Down-regulation
Other_Aur_AURKA_ST	O43521	BCL2L11	O14965	AURKA	S87	R84G	84	Missense	distal	-3	no	42.260	37.066	EPSD	ICGC;COSMIC	39.062	Loss
Other_Aur_AURKA_ST	O43521	BCL2L11	O14965	AURKA	S87	S92Y	92	Missense	distal	5	no	42.260	42.313	EPSD	ICGC	39.062	Up-regulation
Other_Aur_AURKA_ST	O43521	BCL2L11	O14965	AURKA	S90	R84G	84	Missense	distal	-6	no	41.931	38.140	EPSD	ICGC;COSMIC	39.062	Loss
Other_Aur_AURKA_ST	O43521	BCL2L11	O14965	AURKA	S90	G95W	95	Missense	distal	5	no	41.931	41.677	EPSD	ICGC;COSMIC	39.062	Down-regulation
Other_Aur_AURKA_ST	O43521	BCL2L11	O14965	AURKA	S90	S92Y	92	Missense	proximal	2	no	41.931	43.172	EPSD	ICGC	39.062	Up-regulation
Other_Aur_AURKA_ST	O43521	BCL2L11	O14965	AURKA	S93	G95W	95	Missense	proximal	2	no	48.846	47.266	EPSD;PhosphoSitePlus	ICGC;COSMIC	39.062	Down-regulation
Other_Aur_AURKA_ST	O43521	BCL2L11	O14965	AURKA	S93	S92Y	92	Missense	proximal	-1	no	48.846	47.902	EPSD;PhosphoSitePlus	ICGC	39.062	Down-regulation
Other_Aur_AURKA_ST	O43521	BCL2L11	O14965	AURKA	S94	G95W	95	Missense	proximal	1	no	49.381	47.628	EPSD;PhosphoSitePlus	ICGC;COSMIC	39.062	Down-regulation
Other_Aur_AURKA_ST	O43521	BCL2L11	O14965	AURKA	S94	S92Y	92	Missense	proximal	-2	no	49.381	48.663	EPSD;PhosphoSitePlus	ICGC	39.062	Down-regulation
Other_Aur_AURKA_ST	O43521	BCL2L11	O14965	AURKA	S98	G95W	95	Missense	distal	-3	no	47.342	-26.637	PhosphoSitePlus;EPSD	ICGC;COSMIC	39.062	Loss
Other_Aur_AURKA_ST	O43521	BCL2L11	O14965	AURKA	S98	S92Y	92	Missense	distal	-6	no	47.342	45.459	PhosphoSitePlus;EPSD	ICGC	39.062	Down-regulation
Other_Aur_AURKA_ST	O43521	BCL2L11	O14965	AURKA	S113	K112T	112	Missense	proximal	-1	no	40.152	42.213	EPSD	ICGC;COSMIC	39.062	Up-regulation
Other_Aur_AURKA_ST	Q14511	NEDD9	O14965	AURKA	S296	P303S	303	Missense	distal	7	no	48.185	48.295	PhosphoSitePlus	ICGC	39.062	Up-regulation
Other_Aur_AURKA_ST	Q14511	NEDD9	O14965	AURKA	S296	P299L	299	Missense	distal	3	no	48.185	47.721	PhosphoSitePlus	ICGC;COSMIC	39.062	Down-regulation
Other_Aur_AURKA_ST	Q14511	NEDD9	O14965	AURKA	S296	P302Q	302	Missense	distal	6	no	48.185	48.179	PhosphoSitePlus	ICGC;COSMIC	39.062	Down-regulation
Other_Aur_AURKA_ST	Q14511	NEDD9	O14965	AURKA	S296	P302T	302	Missense	distal	6	no	48.185	48.144	PhosphoSitePlus	ICGC	39.062	Down-regulation
Other_Aur_AURKA_ST	Q14511	NEDD9	O14965	AURKA	S296	S296R	296	Missense	central	0	yes	48.185	0.000	PhosphoSitePlus	ICGC	39.062	Loss
Other_Aur_AURKA_ST	Q9ULW0	TPX2	O14965	AURKA	T195	P197L	197	Missense	proximal	2	no	43.550	43.819	EPSD	ICGC;COSMIC	39.062	Up-regulation
Other_Aur_AURKA_ST	Q9ULW0	TPX2	O14965	AURKA	T298	V304F	304	Missense	distal	6	no	39.034	39.269	EPSD	ICGC	39.062	Gain
Other_Aur_AURKA_ST	Q9ULW0	TPX2	O14965	AURKA	T302	I303F	303	Missense	proximal	1	no	36.506	40.809	EPSD	ICGC;COSMIC	39.062	Gain
Other_Aur_AURKA_ST	Q9UPY8	MAPRE3	O14965	AURKA	S40	A42T	42	Missense	proximal	2	no	41.705	40.445	EPSD	ICGC	39.062	Down-regulation
Other_Aur_AURKA_ST	Q9UPY8	MAPRE3	O14965	AURKA	S40	A42S	42	Missense	proximal	2	no	41.705	43.589	EPSD	ICGC	39.062	Up-regulation
Other_Aur_AURKA_ST	Q9UPY8	MAPRE3	O14965	AURKA	S40	G41V	41	Missense	proximal	1	no	41.705	44.045	EPSD	ICGC;COSMIC	39.062	Up-regulation
Other_Aur_AURKA_ST	P04637	TP53	O14965	AURKA	S37	P34L	34	Missense	distal	-3	no	38.012	39.156	EPSD	ICGC;COSMIC	39.062	Gain
Other_Aur_AURKA_ST	P04637	TP53	O14965	AURKA	S106	Q100K	100	Missense	distal	-6	no	42.716	40.598	PhosphoSitePlus;EPSD	ICGC;COSMIC	39.062	Down-regulation
Other_Aur_AURKA_ST	P04637	TP53	O14965	AURKA	S106	F113I	113	Missense	distal	7	no	42.716	42.805	PhosphoSitePlus;EPSD	ICGC;COSMIC	39.062	Up-regulation
Other_Aur_AURKA_ST	P04637	TP53	O14965	AURKA	S106	G105A	105	Missense	proximal	-1	no	42.716	42.769	PhosphoSitePlus;EPSD	ICGC;COSMIC	39.062	Up-regulation
Other_Aur_AURKA_ST	P04637	TP53	O14965	AURKA	S127	T125R	125	Missense	proximal	-2	no	23.360	42.573	EPSD	ICGC;COSMIC	39.062	Gain
Other_Aur_AURKA_ST	P04637	TP53	O14965	AURKA	S183	C182W	182	Missense	proximal	-1	no	41.241	45.132	EPSD	ICGC;COSMIC	39.062	Up-regulation
Other_Aur_AURKA_ST	P04637	TP53	O14965	AURKA	S183	H178D	178	Missense	distal	-5	no	41.241	41.310	EPSD	ICGC;COSMIC;CCLE	39.062	Up-regulation
Other_Aur_AURKA_ST	P04637	TP53	O14965	AURKA	S183	D184H	184	Missense	proximal	1	no	41.241	38.395	EPSD	ICGC;COSMIC	39.062	Loss
Other_Aur_AURKA_ST	P04637	TP53	O14965	AURKA	S183	A189T	189	Missense	distal	6	no	41.241	41.136	EPSD	ICGC;COSMIC	39.062	Down-regulation
Other_Aur_AURKA_ST	P04637	TP53	O14965	AURKA	S183	P190T	190	Missense	distal	7	no	41.241	41.287	EPSD	ICGC;COSMIC	39.062	Up-regulation
Other_Aur_AURKA_ST	P04637	TP53	O14965	AURKA	S183	P190S	190	Missense	distal	7	no	41.241	41.351	EPSD	ICGC;COSMIC	39.062	Up-regulation
Other_Aur_AURKA_ST	P04637	TP53	O14965	AURKA	S183	A189D	189	Missense	distal	6	no	41.241	41.382	EPSD	ICGC;COSMIC	39.062	Up-regulation
Other_Aur_AURKA_ST	P04637	TP53	O14965	AURKA	S183	E180D	180	Missense	distal	-3	no	41.241	40.115	EPSD	ICGC;COSMIC	39.062	Down-regulation
Other_Aur_AURKA_ST	P04637	TP53	O14965	AURKA	S183	C176G	176	Missense	distal	-7	no	41.241	40.561	EPSD	ICGC;COSMIC	39.062	Down-regulation
Other_Aur_AURKA_ST	P04637	TP53	O14965	AURKA	S215	P219T	219	Missense	distal	4	no	49.444	48.482	EPSD;PhosphoSitePlus	ICGC;COSMIC	39.062	Down-regulation
Other_Aur_AURKA_ST	P04637	TP53	O14965	AURKA	S215	H214D	214	Missense	proximal	-1	no	49.444	51.187	EPSD;PhosphoSitePlus	ICGC;COSMIC	39.062	Up-regulation
Other_Aur_AURKA_ST	P04637	TP53	O14965	AURKA	S215	Y220N	220	Missense	distal	5	no	49.444	49.002	EPSD;PhosphoSitePlus	ICGC;COSMIC	39.062	Down-regulation
Other_Aur_AURKA_ST	P04637	TP53	O14965	AURKA	S215	E221V	221	Missense	distal	6	no	49.444	49.415	EPSD;PhosphoSitePlus	ICGC;COSMIC	39.062	Down-regulation
Other_Aur_AURKA_ST	P04637	TP53	O14965	AURKA	S215	E221K	221	Missense	distal	6	no	49.444	49.278	EPSD;PhosphoSitePlus	ICGC;COSMIC	39.062	Down-regulation
Other_Aur_AURKA_ST	P04637	TP53	O14965	AURKA	S215	H214Y	214	Missense	proximal	-1	no	49.444	48.921	EPSD;PhosphoSitePlus	ICGC;COSMIC	39.062	Down-regulation
Other_Aur_AURKA_ST	P04637	TP53	O14965	AURKA	S215	T211P	211	Missense	distal	-4	no	49.444	45.530	EPSD;PhosphoSitePlus	ICGC;COSMIC	39.062	Down-regulation
Other_Aur_AURKA_ST	P04637	TP53	O14965	AURKA	S215	F212V	212	Missense	distal	-3	no	49.444	56.377	EPSD;PhosphoSitePlus	ICGC;COSMIC	39.062	Up-regulation
Other_Aur_AURKA_ST	P04637	TP53	O14965	AURKA	S215	D208V	208	Missense	distal	-7	no	49.444	49.734	EPSD;PhosphoSitePlus	ICGC;COSMIC	39.062	Up-regulation
Other_Aur_AURKA_ST	P04637	TP53	O14965	AURKA	S215	V217G	217	Missense	proximal	2	no	49.444	50.061	EPSD;PhosphoSitePlus	ICGC;COSMIC;CCLE	39.062	Up-regulation
Other_Aur_AURKA_ST	P04637	TP53	O14965	AURKA	S269	A276V	276	Missense	distal	7	no	39.770	39.897	EPSD	ICGC;COSMIC	39.062	Up-regulation
Other_Aur_AURKA_ST	P04637	TP53	O14965	AURKA	S269	V274A	274	Missense	distal	5	no	39.770	40.386	EPSD	ICGC;COSMIC	39.062	Up-regulation
Other_Aur_AURKA_ST	P04637	TP53	O14965	AURKA	S269	V272E	272	Missense	distal	3	no	39.770	41.057	EPSD	ICGC;COSMIC;CCLE	39.062	Up-regulation
Other_Aur_AURKA_ST	P04637	TP53	O14965	AURKA	S269	L265T	265	Missense	distal	-4	no	39.770	42.532	EPSD	ICGC	39.062	Up-regulation
Other_Aur_AURKA_ST	P04637	TP53	O14965	AURKA	S269	N268I	268	Missense	proximal	-1	no	39.770	43.103	EPSD	ICGC;COSMIC;GDSC;CCLE	39.062	Up-regulation
Other_Aur_AURKA_ST	P04637	TP53	O14965	AURKA	S269	E271D	271	Missense	proximal	2	no	39.770	40.540	EPSD	ICGC;COSMIC	39.062	Up-regulation
Other_Aur_AURKA_ST	P04637	TP53	O14965	AURKA	S313	T312I	312	Missense	proximal	-1	no	41.824	41.615	EPSD	ICGC;COSMIC	39.062	Down-regulation
Other_Aur_AURKA_ST	P04637	TP53	O14965	AURKA	S315	T312I	312	Missense	distal	-3	no	43.992	45.338	EPSD;PhosphoSitePlus	ICGC;COSMIC	39.062	Up-regulation
Other_Aur_AURKA_ST	P04637	TP53	O14965	AURKA	S315	P322T	322	Missense	distal	7	no	43.992	44.038	EPSD;PhosphoSitePlus	ICGC	39.062	Up-regulation
Other_Aur_AURKA_ST	Q13526	PIN1	O14965	AURKA	S32	W34L	34	Missense	proximal	2	no	38.688	39.124	EPSD	ICGC;COSMIC	39.062	Gain
Other_Aur_AURKA_ST	Q13526	PIN1	O14965	AURKA	S65	R69W	69	Missense	distal	4	no	45.733	46.686	EPSD	ICGC;COSMIC	39.062	Up-regulation
Other_Aur_AURKA_ST	Q13526	PIN1	O14965	AURKA	S71	E76K	76	Missense	distal	5	no	43.245	43.773	EPSD	ICGC	39.062	Up-regulation
Other_Aur_AURKA_ST	Q13526	PIN1	O14965	AURKA	S71	R69W	69	Missense	proximal	-2	no	43.245	-143.462	EPSD	ICGC;COSMIC	39.062	Loss
Other_Aur_AURKA_ST	Q13526	PIN1	O14965	AURKA	S111	A107T	107	Missense	distal	-4	no	40.034	44.993	EPSD	ICGC;COSMIC	39.062	Up-regulation
Other_Aur_AURKA_ST	Q13526	PIN1	O14965	AURKA	S111	Q109H	109	Missense	proximal	-2	no	40.034	43.435	EPSD	ICGC	39.062	Up-regulation
Other_Aur_AURKA_ST	Q9NWT8	AURKAIP1	O14965	AURKA	S70	L74M	74	Missense	distal	4	no	54.259	55.044	PhosphoSitePlus	ICGC;COSMIC	39.062	Up-regulation
Other_Aur_AURKA_ST	Q9NWT8	AURKAIP1	O14965	AURKA	S70	P66H	66	Missense	distal	-4	no	54.259	50.940	PhosphoSitePlus	ICGC;COSMIC	39.062	Down-regulation
Other_Aur_AURKA_ST	Q8IX03	WWC1	O14965	AURKA	S153	V146F	146	Missense	distal	-7	no	40.898	40.712	EPSD	ICGC	39.062	Down-regulation
Other_Aur_AURKA_ST	Q8IX03	WWC1	O14965	AURKA	S153	S153C	153	Missense	central	0	yes	40.898	0.000	EPSD	ICGC;COSMIC	39.062	Loss
Other_Aur_AURKA_ST	Q8IX03	WWC1	O14965	AURKA	S153	S149L	149	Missense	distal	-4	no	40.898	40.132	EPSD	ICGC	39.062	Down-regulation
Other_Aur_AURKA_ST	Q8IX03	WWC1	O14965	AURKA	S153	K154R	154	Missense	proximal	1	no	40.898	40.233	EPSD	ICGC;COSMIC	39.062	Down-regulation
Other_Aur_AURKA_ST	Q8IX03	WWC1	O14965	AURKA	S270	L266V	266	Missense	distal	-4	no	40.751	42.231	EPSD	ICGC;COSMIC	39.062	Up-regulation
Other_Aur_AURKA_ST	Q8IX03	WWC1	O14965	AURKA	S270	P274L	274	Missense	distal	4	no	40.751	40.898	EPSD	ICGC	39.062	Up-regulation
Other_Aur_AURKA_ST	Q8IX03	WWC1	O14965	AURKA	S270	Y277C	277	Missense	distal	7	no	40.751	40.694	EPSD	ICGC;COSMIC;CCLE	39.062	Down-regulation
Other_Aur_AURKA_ST	Q8IX03	WWC1	O14965	AURKA	S270	S268I	268	Missense	proximal	-2	no	40.751	34.881	EPSD	ICGC;COSMIC	39.062	Loss
Other_Aur_AURKA_ST	Q8IX03	WWC1	O14965	AURKA	S539	P536Q	536	Missense	distal	-3	no	48.897	47.893	PhosphoSitePlus	ICGC;COSMIC	39.062	Down-regulation
Other_Aur_AURKA_ST	Q8IX03	WWC1	O14965	AURKA	S539	S539P	539	Missense	central	0	yes	48.897	0.000	PhosphoSitePlus	ICGC;COSMIC	39.062	Loss
Other_Aur_AURKA_ST	Q8IX03	WWC1	O14965	AURKA	S539	S542T	542	Missense	distal	3	no	48.897	46.311	PhosphoSitePlus	ICGC;COSMIC	39.062	Down-regulation
Other_Aur_AURKA_ST	Q8IX03	WWC1	O14965	AURKA	S539	S535F	535	Missense	distal	-4	no	48.897	44.848	PhosphoSitePlus	ICGC	39.062	Down-regulation
Other_Aur_AURKA_ST	Q8IX03	WWC1	O14965	AURKA	S539	S541F	541	Missense	proximal	2	no	48.897	48.201	PhosphoSitePlus	ICGC	39.062	Down-regulation
Other_Aur_AURKA_ST	Q8IX03	WWC1	O14965	AURKA	S626	G632V	632	Missense	distal	6	no	43.745	43.657	EPSD	ICGC;COSMIC	39.062	Down-regulation
Other_Aur_AURKA_ST	Q8IX03	WWC1	O14965	AURKA	S793	K791R	791	Missense	proximal	-2	no	37.870	44.374	EPSD	ICGC	39.062	Gain
Other_Aur_AURKA_ST	Q8IX03	WWC1	O14965	AURKA	S815	T811M	811	Missense	distal	-4	no	39.603	36.783	EPSD	ICGC;COSMIC	39.062	Loss
Other_Aur_AURKA_ST	Q8IX03	WWC1	O14965	AURKA	S815	A809V	809	Missense	distal	-6	no	39.603	38.767	EPSD	ICGC;COSMIC	39.062	Loss
Other_Aur_AURKA_ST	Q8IX03	WWC1	O14965	AURKA	S876	M879R	879	Missense	distal	3	no	42.717	41.775	EPSD	ICGC;COSMIC	39.062	Down-regulation
Other_Aur_AURKA_ST	Q8IX03	WWC1	O14965	AURKA	T912	R908W	908	Missense	distal	-4	no	41.443	33.539	EPSD	ICGC;COSMIC	39.062	Loss
Other_Aur_AURKA_ST	Q8IX03	WWC1	O14965	AURKA	T912	V910L	910	Missense	proximal	-2	no	41.443	42.762	EPSD	ICGC	39.062	Up-regulation
Other_Aur_AURKA_ST	Q8IX03	WWC1	O14965	AURKA	S962	S962F	962	Missense	central	0	yes	39.988	0.000	EPSD	ICGC	39.062	Loss
Other_Aur_AURKA_ST	Q8IX03	WWC1	O14965	AURKA	S978	S975L	975	Missense	distal	-3	no	54.263	53.226	EPSD	ICGC;COSMIC	39.062	Down-regulation
Other_Aur_AURKA_ST	Q8IX03	WWC1	O14965	AURKA	S978	R983C	983	Missense	distal	5	no	54.263	56.413	EPSD	ICGC;COSMIC	39.062	Up-regulation
Other_Aur_AURKA_ST	Q8IX03	WWC1	O14965	AURKA	S978	R980H	980	Missense	proximal	2	no	54.263	53.158	EPSD	ICGC;COSMIC	39.062	Down-regulation
Other_Aur_AURKA_ST	Q8IX03	WWC1	O14965	AURKA	S978	P973L	973	Missense	distal	-5	no	54.263	54.275	EPSD	ICGC;COSMIC	39.062	Up-regulation
Other_Aur_AURKA_ST	Q8IX03	WWC1	O14965	AURKA	S978	E982K	982	Missense	distal	4	no	54.263	54.247	EPSD	ICGC;COSMIC	39.062	Down-regulation
Other_Aur_AURKA_ST	Q8IX03	WWC1	O14965	AURKA	S978	R980C	980	Missense	proximal	2	no	54.263	57.416	EPSD	ICGC;COSMIC	39.062	Up-regulation
Other_Aur_AURKA_ST	Q8IX03	WWC1	O14965	AURKA	S978	S981C	981	Missense	distal	3	no	54.263	51.925	EPSD	ICGC;COSMIC	39.062	Down-regulation
Other_Aur_AURKA_ST	Q8IX03	WWC1	O14965	AURKA	S978	R983P	983	Missense	distal	5	no	54.263	54.754	EPSD	ICGC;COSMIC	39.062	Up-regulation
Other_Aur_AURKA_ST	Q8IX03	WWC1	O14965	AURKA	S978	R983H	983	Missense	distal	5	no	54.263	54.771	EPSD	ICGC;COSMIC	39.062	Up-regulation
Other_Aur_AURKA_ST	Q8IX03	WWC1	O14965	AURKA	S978	P973S	973	Missense	distal	-5	no	54.263	54.284	EPSD	ICGC;COSMIC	39.062	Up-regulation
Other_Aur_AURKA_ST	P10275	AR	O14965	AURKA	T282	A288T	288	Missense	distal	6	no	46.920	46.816	PhosphoSitePlus;EPSD	ICGC;COSMIC	39.062	Down-regulation
Other_Aur_AURKA_ST	P10275	AR	O14965	AURKA	T282	R280L	280	Missense	proximal	-2	no	46.920	37.199	PhosphoSitePlus;EPSD	ICGC	39.062	Loss
Other_Aur_AURKA_ST	P10275	AR	O14965	AURKA	T282	A288D	288	Missense	distal	6	no	46.920	47.062	PhosphoSitePlus;EPSD	ICGC;COSMIC	39.062	Up-regulation
Other_Aur_AURKA_ST	P10275	AR	O14965	AURKA	S293	G300V	300	Missense	distal	7	no	46.780	46.735	EPSD;PhosphoSitePlus	ICGC;COSMIC	39.062	Down-regulation
Other_Aur_AURKA_ST	P10275	AR	O14965	AURKA	S293	C290Y	290	Missense	distal	-3	no	46.780	41.701	EPSD;PhosphoSitePlus	ICGC;COSMIC	39.062	Down-regulation
Other_Aur_AURKA_ST	P10275	AR	O14965	AURKA	S293	A288T	288	Missense	distal	-5	no	46.780	46.819	EPSD;PhosphoSitePlus	ICGC;COSMIC	39.062	Up-regulation
Other_Aur_AURKA_ST	P10275	AR	O14965	AURKA	S293	A299V	299	Missense	distal	6	no	46.780	46.683	EPSD;PhosphoSitePlus	ICGC	39.062	Down-regulation
Other_Aur_AURKA_ST	P10275	AR	O14965	AURKA	S293	A288D	288	Missense	distal	-5	no	46.780	46.827	EPSD;PhosphoSitePlus	ICGC;COSMIC	39.062	Up-regulation
Other_Aur_AURKA_ST	P10275	AR	O14965	AURKA	S298	G300V	300	Missense	proximal	2	no	39.510	38.893	EPSD	ICGC;COSMIC	39.062	Loss
Other_Aur_AURKA_ST	P10275	AR	O14965	AURKA	S298	T303S	303	Missense	distal	5	no	39.510	39.179	EPSD	ICGC;COSMIC	39.062	Down-regulation
Other_Aur_AURKA_ST	P10275	AR	O14965	AURKA	S298	A299V	299	Missense	proximal	1	no	39.510	39.330	EPSD	ICGC	39.062	Down-regulation
Other_Aur_AURKA_ST	P10275	AR	O14965	AURKA	S336	A333S	333	Missense	distal	-3	no	39.251	40.663	EPSD	ICGC;COSMIC	39.062	Up-regulation
Other_Aur_AURKA_ST	P10275	AR	O14965	AURKA	S792	C785F	785	Missense	distal	-7	no	40.139	40.603	EPSD	ICGC	39.062	Up-regulation
Other_Aur_AURKA_ST	P10275	AR	O14965	AURKA	S792	R789S	789	Missense	distal	-3	no	40.139	33.660	EPSD	ICGC	39.062	Loss
Other_Aur_AURKA_ST	O15360	FANCA	O14965	AURKA	S165	Q168E	168	Missense	distal	3	no	47.693	48.080	PhosphoSitePlus	ICGC;COSMIC	39.062	Up-regulation
Other_Aur_AURKA_ST	O15360	FANCA	O14965	AURKA	S309	H305Q	305	Missense	distal	-4	no	37.059	41.648	EPSD	ICGC	39.062	Gain
Other_Aur_AURKA_ST	O15360	FANCA	O14965	AURKA	S309	H305R	305	Missense	distal	-4	no	37.059	41.494	EPSD	ICGC	39.062	Gain
Other_Aur_AURKA_ST	O15360	FANCA	O14965	AURKA	S421	C422Y	422	Missense	proximal	1	no	35.491	41.482	EPSD	ICGC;COSMIC	39.062	Gain
Other_Aur_AURKA_ST	O15360	FANCA	O14965	AURKA	S1149	R1144L	1144	Missense	distal	-5	no	51.498	51.485	EPSD	ICGC;COSMIC	39.062	Down-regulation
Other_Aur_AURKA_ST	O15360	FANCA	O14965	AURKA	S1301	A1304T	1304	Missense	distal	3	no	48.087	46.955	EPSD	ICGC;COSMIC	39.062	Down-regulation
Other_Aur_AURKA_ST	O15360	FANCA	O14965	AURKA	S1301	A1304E	1304	Missense	distal	3	no	48.087	49.252	EPSD	ICGC	39.062	Up-regulation
Other_Aur_AURKA_ST	P53667	LIMK1	O14965	AURKA	S298	R295Q	295	Missense	distal	-3	no	41.520	31.856	EPSD	ICGC;COSMIC	39.062	Loss
Other_Aur_AURKA_ST	Q9BXS6	NUSAP1	O14965	AURKA	S149	R152T	152	Missense	distal	3	no	46.924	45.403	EPSD	ICGC;COSMIC	39.062	Down-regulation
Other_Aur_AURKA_ST	Q9BXS6	NUSAP1	O14965	AURKA	S154	R152T	152	Missense	proximal	-2	no	40.925	21.712	EPSD	ICGC;COSMIC	39.062	Loss
Other_Aur_AURKA_ST	Q9BXS6	NUSAP1	O14965	AURKA	S215	M216I	216	Missense	proximal	1	no	39.568	37.005	EPSD	ICGC	39.062	Loss
Other_Aur_AURKA_ST	Q9BXS6	NUSAP1	O14965	AURKA	S243	R249Q	249	Missense	distal	6	no	42.899	42.856	EPSD	ICGC;COSMIC	39.062	Down-regulation
Other_Aur_AURKA_ST	Q9BXS6	NUSAP1	O14965	AURKA	S251	R249Q	249	Missense	proximal	-2	no	43.033	32.394	EPSD	ICGC;COSMIC	39.062	Loss
Other_Aur_AURKA_ST	Q9BXS6	NUSAP1	O14965	AURKA	S276	A278S	278	Missense	proximal	2	no	38.153	40.037	EPSD	ICGC;COSMIC	39.062	Gain
Other_Aur_AURKA_ST	Q9BXS6	NUSAP1	O14965	AURKA	S285	G281C	281	Missense	distal	-4	no	46.790	43.908	EPSD	ICGC	39.062	Down-regulation
Other_Aur_AURKA_ST	Q9BXS6	NUSAP1	O14965	AURKA	S285	A278S	278	Missense	distal	-7	no	46.790	46.905	EPSD	ICGC;COSMIC	39.062	Up-regulation
Other_Aur_AURKA_ST	Q9BXS6	NUSAP1	O14965	AURKA	T309	A306S	306	Missense	distal	-3	no	43.538	44.951	EPSD	ICGC	39.062	Up-regulation
Other_Aur_AURKA_ST	Q9BXS6	NUSAP1	O14965	AURKA	T309	P315T	315	Missense	distal	6	no	43.538	43.497	EPSD	ICGC;COSMIC	39.062	Down-regulation
Other_Aur_AURKA_ST	Q9BXS6	NUSAP1	O14965	AURKA	S363	N369T	369	Missense	distal	6	no	40.882	41.042	EPSD	ICGC	39.062	Up-regulation
Other_Aur_AURKA_ST	P49450	CENPA	O14965	AURKA	S32	S36F	36	Missense	distal	4	no	45.951	46.434	EPSD	ICGC	39.062	Up-regulation
Other_Aur_AURKA_ST	P49736	MCM2	O14965	AURKA	S32	R33Q	33	Missense	proximal	1	no	38.758	39.649	EPSD	ICGC	39.062	Gain
Other_Aur_AURKA_ST	P49736	MCM2	O14965	AURKA	T158	G161C	161	Missense	distal	3	no	43.684	41.752	EPSD	ICGC	39.062	Down-regulation
Other_Aur_AURKA_ST	P49736	MCM2	O14965	AURKA	S220	D221N	221	Missense	proximal	1	no	55.596	50.022	PhosphoSitePlus	ICGC;COSMIC	39.062	Down-regulation
Other_Aur_AURKA_ST	P49736	MCM2	O14965	AURKA	S220	N213S	213	Missense	distal	-7	no	55.596	56.260	PhosphoSitePlus	ICGC	39.062	Up-regulation
Other_Aur_AURKA_ST	P49736	MCM2	O14965	AURKA	S220	N213Y	213	Missense	distal	-7	no	55.596	56.447	PhosphoSitePlus	ICGC;COSMIC	39.062	Up-regulation
Other_Aur_AURKA_ST	P49736	MCM2	O14965	AURKA	S220	V214F	214	Missense	distal	-6	no	55.596	50.557	PhosphoSitePlus	ICGC	39.062	Down-regulation
Other_Aur_AURKA_ST	P49736	MCM2	O14965	AURKA	S599	D594Y	594	Missense	distal	-5	no	42.613	42.607	EPSD	ICGC	39.062	Down-regulation
Other_Aur_AURKA_ST	P49736	MCM2	O14965	AURKA	S754	P761S	761	Missense	distal	7	no	43.194	43.304	EPSD	ICGC;COSMIC	39.062	Up-regulation
Other_Aur_AURKA_ST	P49736	MCM2	O14965	AURKA	S754	S754A	754	Missense	central	0	yes	43.194	0.000	EPSD	ICGC	39.062	Loss
Other_Aur_AURKA_ST	P49736	MCM2	O14965	AURKA	S754	T757A	757	Missense	distal	3	no	43.194	44.326	EPSD	ICGC	39.062	Up-regulation
Other_Aur_AURKA_ST	O75496	GMNN	O14965	AURKA	S45	L48F	48	Missense	distal	3	no	40.010	41.180	EPSD	ICGC;COSMIC	39.062	Up-regulation
Other_Aur_AURKA_ST	Q9Y6A5	TACC3	O14965	AURKA	S34	S39P	39	Missense	distal	5	no	51.131	50.470	EPSD	ICGC;COSMIC	39.062	Down-regulation
Other_Aur_AURKA_ST	Q9Y6A5	TACC3	O14965	AURKA	S34	R37C	37	Missense	distal	3	no	51.131	49.858	EPSD	ICGC;COSMIC;GDSC	39.062	Down-regulation
Other_Aur_AURKA_ST	Q9Y6A5	TACC3	O14965	AURKA	S34	G31R	31	Missense	distal	-3	no	51.131	56.325	EPSD	ICGC;COSMIC	39.062	Up-regulation
Other_Aur_AURKA_ST	Q9Y6A5	TACC3	O14965	AURKA	S34	S33L	33	Missense	proximal	-1	no	51.131	49.562	EPSD	ICGC;COSMIC	39.062	Down-regulation
Other_Aur_AURKA_ST	Q9Y6A5	TACC3	O14965	AURKA	S39	S39P	39	Missense	central	0	yes	40.106	0.000	EPSD	ICGC;COSMIC	39.062	Loss
Other_Aur_AURKA_ST	Q9Y6A5	TACC3	O14965	AURKA	S39	R37C	37	Missense	proximal	-2	no	40.106	24.809	EPSD	ICGC;COSMIC;GDSC	39.062	Loss
Other_Aur_AURKA_ST	Q9Y6A5	TACC3	O14965	AURKA	S39	S33L	33	Missense	distal	-6	no	40.106	38.575	EPSD	ICGC;COSMIC	39.062	Loss
Other_Aur_AURKA_ST	Q9Y6A5	TACC3	O14965	AURKA	T87	T87I	87	Missense	central	0	yes	47.660	0.000	EPSD	ICGC	39.062	Loss
Other_Aur_AURKA_ST	Q9Y6A5	TACC3	O14965	AURKA	T87	E91V	91	Missense	distal	4	no	47.660	46.940	EPSD	ICGC;COSMIC	39.062	Down-regulation
Other_Aur_AURKA_ST	Q9Y6A5	TACC3	O14965	AURKA	T87	Q84H	84	Missense	distal	-3	no	47.660	51.551	EPSD	ICGC;COSMIC	39.062	Up-regulation
Other_Aur_AURKA_ST	Q9Y6A5	TACC3	O14965	AURKA	T87	H94R	94	Missense	distal	7	no	47.660	47.655	EPSD	ICGC;COSMIC	39.062	Down-regulation
Other_Aur_AURKA_ST	Q9Y6A5	TACC3	O14965	AURKA	S330	M327I	327	Missense	distal	-3	no	37.150	41.778	EPSD	ICGC;COSMIC	39.062	Gain
Other_Aur_AURKA_ST	Q9Y6A5	TACC3	O14965	AURKA	S402	P395R	395	Missense	distal	-7	no	46.420	45.133	EPSD	ICGC;COSMIC	39.062	Down-regulation
Other_Aur_AURKA_ST	Q9Y6A5	TACC3	O14965	AURKA	S402	D408Y	408	Missense	distal	6	no	46.420	46.201	EPSD	ICGC	39.062	Down-regulation
Other_Aur_AURKA_ST	Q9Y6A5	TACC3	O14965	AURKA	S558	D564N	564	Missense	distal	6	no	53.776	53.369	PhosphoSitePlus	ICGC;COSMIC	39.062	Down-regulation
Other_Aur_AURKA_ST	Q9Y6A5	TACC3	O14965	AURKA	S558	K556R	556	Missense	proximal	-2	no	53.776	60.280	PhosphoSitePlus	ICGC	39.062	Up-regulation
Other_Aur_AURKA_ST	Q9Y6A5	TACC3	O14965	AURKA	S558	P565T	565	Missense	distal	7	no	53.776	53.822	PhosphoSitePlus	ICGC;COSMIC	39.062	Up-regulation
Other_Aur_AURKA_ST	Q9Y6A5	TACC3	O14965	AURKA	S558	Q557E	557	Missense	proximal	-1	no	53.776	53.349	PhosphoSitePlus	ICGC;COSMIC	39.062	Down-regulation
Other_Aur_AURKA_ST	Q9Y6A5	TACC3	O14965	AURKA	S570	V577L	577	Missense	distal	7	no	48.144	48.043	EPSD	ICGC;COSMIC	39.062	Down-regulation
Other_Aur_AURKA_ST	Q9Y6A5	TACC3	O14965	AURKA	S570	D564N	564	Missense	distal	-6	no	48.144	54.164	EPSD	ICGC;COSMIC	39.062	Up-regulation
Other_Aur_AURKA_ST	Q9Y6A5	TACC3	O14965	AURKA	S570	G572D	572	Missense	proximal	2	no	48.144	49.204	EPSD	ICGC	39.062	Up-regulation
Other_Aur_AURKA_ST	Q9Y6A5	TACC3	O14965	AURKA	S570	P565T	565	Missense	distal	-5	no	48.144	48.173	EPSD	ICGC;COSMIC	39.062	Up-regulation
Other_Aur_AURKA_ST	P25490	YY1	O14965	AURKA	S165	G170S	170	Missense	distal	5	no	45.006	44.905	EPSD	ICGC;COSMIC	39.062	Down-regulation
Other_Aur_AURKA_ST	P25490	YY1	O14965	AURKA	S252	N246S	246	Missense	distal	-6	no	42.387	39.182	EPSD	ICGC	39.062	Down-regulation
Other_Aur_AURKA_ST	P25490	YY1	O14965	AURKA	S252	P248H	248	Missense	distal	-4	no	42.387	39.068	EPSD	ICGC;COSMIC	39.062	Down-regulation
Other_Aur_AURKA_ST	P25490	YY1	O14965	AURKA	T348	Q344K	344	Missense	distal	-4	no	37.527	39.082	EPSD	ICGC;COSMIC	39.062	Gain
Other_Aur_AURKA_ST	P25490	YY1	O14965	AURKA	S365	F368Y	368	Missense	distal	3	no	45.539	45.473	PhosphoSitePlus	ICGC;COSMIC	39.062	Down-regulation
Other_Aur_AURKA_ST	P25490	YY1	O14965	AURKA	S365	G361V	361	Missense	distal	-4	no	45.539	47.373	PhosphoSitePlus	ICGC;COSMIC	39.062	Up-regulation
Other_Aur_AURKA_ST	P30305	CDC25B	O14965	AURKA	T86	T86M	86	Missense	central	0	yes	39.121	0.000	EPSD	ICGC;COSMIC	39.062	Loss
Other_Aur_AURKA_ST	P30305	CDC25B	O14965	AURKA	S89	T86M	86	Missense	distal	-3	no	42.061	38.779	EPSD	ICGC;COSMIC	39.062	Loss
Other_Aur_AURKA_ST	P30305	CDC25B	O14965	AURKA	S115	D120Y	120	Missense	distal	5	no	43.504	42.623	EPSD	ICGC	39.062	Down-regulation
Other_Aur_AURKA_ST	P30305	CDC25B	O14965	AURKA	S327	M324R	324	Missense	distal	-3	no	30.611	43.508	EPSD	ICGC;COSMIC	39.062	Gain
Other_Aur_AURKA_ST	P30305	CDC25B	O14965	AURKA	S375	E382G	382	Missense	distal	7	no	39.179	39.249	EPSD	ICGC;COSMIC	39.062	Up-regulation
Atypical_GTF2F1_GTF2F1_ST	P13631	RARG	P35269	GTF2F1	S36	S43R	43	Missense	distal	7	no	1.963	1.967	EPSD	ICGC	1.654	Up-regulation
Atypical_GTF2F1_GTF2F1_ST	P13631	RARG	P35269	GTF2F1	S36	A32E	32	Missense	distal	-4	no	1.963	1.980	EPSD	ICGC	1.654	Up-regulation
Atypical_GTF2F1_GTF2F1_ST	P13631	RARG	P35269	GTF2F1	S36	L42P	42	Missense	distal	6	no	1.963	1.789	EPSD	ICGC;COSMIC	1.654	Down-regulation
Atypical_GTF2F1_GTF2F1_ST	P13631	RARG	P35269	GTF2F1	S43	S43R	43	Missense	central	0	yes	3.549	0.000	EPSD	ICGC	1.654	Loss
Atypical_GTF2F1_GTF2F1_ST	P13631	RARG	P35269	GTF2F1	S43	P44T	44	Missense	proximal	1	no	3.549	2.030	EPSD	ICGC	1.654	Down-regulation
Atypical_GTF2F1_GTF2F1_ST	P13631	RARG	P35269	GTF2F1	S43	L42P	42	Missense	proximal	-1	no	3.549	3.333	EPSD	ICGC;COSMIC	1.654	Down-regulation
Atypical_GTF2F1_GTF2F1_ST	P13631	RARG	P35269	GTF2F1	S426	P431H	431	Missense	distal	5	no	2.052	-0.151	EPSD	ICGC	1.654	Loss
Atypical_GTF2F1_GTF2F1_ST	P13631	RARG	P35269	GTF2F1	S426	P431S	431	Missense	distal	5	no	2.052	-0.057	EPSD	ICGC;COSMIC	1.654	Loss
AGC_NDR_LATS_LATS1_ST	Q9NQS7	INCENP	O95835	LATS1	S103	S98C	98	Missense	distal	-5	no	0.002	0.003	EPSD	ICGC	0.001	Up-regulation
AGC_NDR_LATS_LATS1_ST	Q9NQS7	INCENP	O95835	LATS1	S103	R100C	100	Missense	distal	-3	no	0.002	0.000	EPSD	ICGC;COSMIC	0.001	Loss
AGC_NDR_LATS_LATS1_ST	Q9NQS7	INCENP	O95835	LATS1	T292	P287R	287	Missense	distal	-5	no	0.000	0.001	EPSD	ICGC	0.001	Gain
AGC_NDR_LATS_LATS1_ST	Q9NQS7	INCENP	O95835	LATS1	S302	S302L	302	Missense	central	0	yes	0.001	0.000	EPSD	ICGC;COSMIC	0.001	Loss
AGC_NDR_LATS_LATS1_ST	Q9NQS7	INCENP	O95835	LATS1	S330	V325L	325	Missense	distal	-5	no	0.000	0.001	EPSD	ICGC;COSMIC	0.001	Gain
AGC_NDR_LATS_LATS1_ST	Q9NQS7	INCENP	O95835	LATS1	S357	R352H	352	Missense	distal	-5	no	0.001	0.002	EPSD	ICGC;GDSC;CCLE	0.001	Up-regulation
AGC_NDR_LATS_LATS1_ST	Q9NQS7	INCENP	O95835	LATS1	S400	G397R	397	Missense	distal	-3	no	0.000	0.003	EPSD	ICGC	0.001	Gain
AGC_NDR_LATS_LATS1_ST	Q9NQS7	INCENP	O95835	LATS1	S518	R513H	513	Missense	distal	-5	no	0.001	0.002	EPSD	ICGC;GDSC;CCLE	0.001	Up-regulation
AGC_NDR_LATS_LATS1_ST	P46937	YAP1	O95835	LATS1	S164	R161L	161	Missense	distal	-3	no	0.005	0.002	EPSD;PhosphoSitePlus	ICGC	0.001	Down-regulation
AGC_NDR_LATS_LATS1_ST	P46937	YAP1	O95835	LATS1	S164	S164F	164	Missense	central	0	yes	0.005	0.000	EPSD;PhosphoSitePlus	ICGC	0.001	Loss
AGC_NDR_LATS_LATS1_ST	P46937	YAP1	O95835	LATS1	S184	S184F	184	Missense	central	0	yes	0.001	0.000	EPSD	ICGC;COSMIC	0.001	Loss
AGC_NDR_LATS_LATS1_ST	P46937	YAP1	O95835	LATS1	S336	R331W	331	Missense	distal	-5	no	0.001	0.000	EPSD	ICGC;COSMIC	0.001	Loss
AGC_NDR_LATS_LATS1_ST	P46937	YAP1	O95835	LATS1	S397	R394Q	394	Missense	distal	-3	no	0.005	0.002	EPSD	ICGC;COSMIC	0.001	Down-regulation
AGC_NDR_LATS_LATS1_ST	P46937	YAP1	O95835	LATS1	S397	S397I	397	Missense	central	0	yes	0.005	0.000	EPSD	ICGC	0.001	Loss
AGC_NDR_LATS_LATS1_ST	P46937	YAP1	O95835	LATS1	S397	H392N	392	Missense	distal	-5	no	0.005	0.003	EPSD	ICGC;COSMIC	0.001	Down-regulation
AGC_NDR_LATS_LATS1_ST	Q8NHZ8	CDC26	O95835	LATS1	S56	S51R	51	Missense	distal	-5	no	0.000	0.001	EPSD	ICGC;COSMIC	0.001	Gain
AGC_NDR_LATS_LATS1_ST	O95835	LATS1	O95835	LATS1	T17	T17N	17	Missense	central	0	yes	0.002	0.000	EPSD	ICGC	0.001	Loss
AGC_NDR_LATS_LATS1_ST	O95835	LATS1	O95835	LATS1	S42	S45Y	45	Missense	distal	3	no	0.003	0.002	EPSD	ICGC;COSMIC	0.001	Down-regulation
AGC_NDR_LATS_LATS1_ST	O95835	LATS1	O95835	LATS1	S674	M669I	669	Missense	distal	-5	no	0.001	0.000	PhosphoSitePlus;EPSD	ICGC;COSMIC	0.001	Loss
AGC_NDR_LATS_LATS1_ST	O95835	LATS1	O95835	LATS1	S909	S909F	909	Missense	central	0	yes	0.001	0.000	EPSD;PhosphoSitePlus	ICGC;COSMIC	0.001	Loss
AGC_NDR_LATS_LATS1_ST	O95835	LATS1	O95835	LATS1	T913	T913I	913	Missense	central	0	yes	0.002	0.000	EPSD	ICGC;COSMIC	0.001	Loss
AGC_NDR_LATS_LATS1_ST	P04049	RAF1	O95835	LATS1	S43	R40C	40	Missense	distal	-3	no	0.003	0.000	EPSD	ICGC;COSMIC	0.001	Loss
AGC_NDR_LATS_LATS1_ST	P04049	RAF1	O95835	LATS1	S220	S220C	220	Missense	central	0	yes	0.001	0.000	EPSD	ICGC	0.001	Loss
AGC_NDR_LATS_LATS1_ST	Q4VCS5	AMOT	O95835	LATS1	S182	R177P	177	Missense	distal	-5	no	0.001	0.000	EPSD	ICGC;COSMIC	0.001	Loss
AGC_NDR_LATS_LATS1_ST	Q4VCS5	AMOT	O95835	LATS1	T709	R706S	706	Missense	distal	-3	no	0.002	-0.001	EPSD	ICGC;COSMIC	0.001	Loss
AGC_NDR_LATS_LATS1_ST	Q4VCS5	AMOT	O95835	LATS1	S855	S852L	852	Missense	distal	-3	no	0.000	0.001	EPSD	ICGC	0.001	Gain
AGC_NDR_LATS_LATS1_ST	Q9GZV5	WWTR1	O95835	LATS1	S87	A82V	82	Missense	distal	-5	no	0.000	0.001	EPSD	ICGC;COSMIC	0.001	Gain
AGC_NDR_LATS_LATS1_ST	Q9GZV5	WWTR1	O95835	LATS1	T292	T292P	292	Missense	central	0	yes	0.003	0.000	EPSD	ICGC	0.001	Loss
TK_PDGFR_PDGFRB_Y	P09619	PDGFRB	P09619	PDGFRB	Y562	R561S	561	Missense	proximal	-1	no	62.833	69.104	EPSD;PhosphoSitePlus	ICGC	43.065	Up-regulation
TK_PDGFR_PDGFRB_Y	P09619	PDGFRB	P09619	PDGFRB	Y579	S573R	573	Missense	distal	-6	no	65.421	74.890	EPSD;PhosphoSitePlus	ICGC	43.065	Up-regulation
TK_PDGFR_PDGFRB_Y	P09619	PDGFRB	P09619	PDGFRB	Y579	H577N	577	Missense	proximal	-2	no	65.421	69.320	EPSD;PhosphoSitePlus	ICGC	43.065	Up-regulation
TK_PDGFR_PDGFRB_Y	P09619	PDGFRB	P09619	PDGFRB	Y579	P584H	584	Missense	distal	5	no	65.421	49.565	EPSD;PhosphoSitePlus	ICGC;COSMIC	43.065	Down-regulation
TK_PDGFR_PDGFRB_Y	P09619	PDGFRB	P09619	PDGFRB	Y581	H577N	577	Missense	distal	-4	no	62.169	62.780	EPSD;PhosphoSitePlus	ICGC	43.065	Up-regulation
TK_PDGFR_PDGFRB_Y	P09619	PDGFRB	P09619	PDGFRB	Y581	P584H	584	Missense	distal	3	no	62.169	62.140	EPSD;PhosphoSitePlus	ICGC;COSMIC	43.065	Down-regulation
TK_PDGFR_PDGFRB_Y	P09619	PDGFRB	P09619	PDGFRB	Y589	T592K	592	Missense	distal	3	no	60.161	60.049	EPSD	ICGC	43.065	Down-regulation
TK_PDGFR_PDGFRB_Y	P09619	PDGFRB	P09619	PDGFRB	Y589	W593C	593	Missense	distal	4	no	60.161	60.154	EPSD	ICGC;COSMIC	43.065	Down-regulation
TK_PDGFR_PDGFRB_Y	P09619	PDGFRB	P09619	PDGFRB	Y589	P584H	584	Missense	distal	-5	no	60.161	61.042	EPSD	ICGC;COSMIC	43.065	Up-regulation
TK_PDGFR_PDGFRB_Y	P09619	PDGFRB	P09619	PDGFRB	Y716	P710Q	710	Missense	distal	-6	no	64.419	65.418	EPSD	ICGC	43.065	Up-regulation
TK_PDGFR_PDGFRB_Y	P09619	PDGFRB	P09619	PDGFRB	Y716	A719P	719	Missense	distal	3	no	64.419	64.692	EPSD	ICGC;COSMIC	43.065	Up-regulation
TK_PDGFR_PDGFRB_Y	P09619	PDGFRB	P09619	PDGFRB	Y716	E714K	714	Missense	proximal	-2	no	64.419	64.914	EPSD	ICGC;COSMIC	43.065	Up-regulation
TK_PDGFR_PDGFRB_Y	P09619	PDGFRB	P09619	PDGFRB	Y740	E735K	735	Missense	distal	-5	no	66.534	65.798	EPSD;PhosphoSitePlus	ICGC;COSMIC	43.065	Down-regulation
TK_PDGFR_PDGFRB_Y	P09619	PDGFRB	P09619	PDGFRB	Y763	A764E	764	Missense	proximal	1	no	65.240	59.783	EPSD;PhosphoSitePlus	ICGC	43.065	Down-regulation
TK_PDGFR_PDGFRB_Y	P09619	PDGFRB	P09619	PDGFRB	Y763	G759V	759	Missense	distal	-4	no	65.240	65.047	EPSD;PhosphoSitePlus	ICGC;COSMIC	43.065	Down-regulation
TK_PDGFR_PDGFRB_Y	P09619	PDGFRB	P09619	PDGFRB	Y771	A764E	764	Missense	distal	-7	no	66.784	64.971	EPSD;PhosphoSitePlus	ICGC	43.065	Down-regulation
TK_PDGFR_PDGFRB_Y	P09619	PDGFRB	P09619	PDGFRB	Y775	P780T	780	Missense	distal	5	no	66.836	48.659	EPSD;PhosphoSitePlus	ICGC	43.065	Down-regulation
TK_PDGFR_PDGFRB_Y	P09619	PDGFRB	P09619	PDGFRB	Y778	P780T	780	Missense	proximal	2	no	65.044	62.276	EPSD;PhosphoSitePlus	ICGC	43.065	Down-regulation
TK_PDGFR_PDGFRB_Y	P09619	PDGFRB	P09619	PDGFRB	Y857	R853L	853	Missense	distal	-4	no	68.992	67.229	EPSD;PhosphoSitePlus	ICGC;COSMIC	43.065	Down-regulation
TK_PDGFR_PDGFRB_Y	P09619	PDGFRB	P09619	PDGFRB	Y1021	D1018G	1018	Missense	distal	-3	no	59.451	52.426	PhosphoSitePlus;EPSD	ICGC;COSMIC	43.065	Down-regulation
TK_PDGFR_PDGFRB_Y	P09619	PDGFRB	P09619	PDGFRB	Y1021	D1020N	1020	Missense	proximal	-1	no	59.451	61.505	PhosphoSitePlus;EPSD	ICGC;COSMIC;CCLE	43.065	Up-regulation
TK_PDGFR_PDGFRB_Y	P16234	PDGFRA	P09619	PDGFRB	Y572	P567L	567	Missense	distal	-5	no	50.468	52.456	EPSD	ICGC;COSMIC	43.065	Up-regulation
TK_PDGFR_PDGFRB_Y	P16234	PDGFRA	P09619	PDGFRB	Y572	D576G	576	Missense	distal	4	no	50.468	50.682	EPSD	ICGC;COSMIC	43.065	Up-regulation
TK_PDGFR_PDGFRB_Y	P16234	PDGFRA	P09619	PDGFRB	Y574	P567L	567	Missense	distal	-7	no	51.135	45.227	EPSD	ICGC;COSMIC	43.065	Down-regulation
TK_PDGFR_PDGFRB_Y	P16234	PDGFRA	P09619	PDGFRB	Y574	D576G	576	Missense	proximal	2	no	51.135	40.214	EPSD	ICGC;COSMIC	43.065	Loss
TK_PDGFR_PDGFRB_Y	P16234	PDGFRA	P09619	PDGFRB	Y582	D576G	576	Missense	distal	-6	no	57.225	54.002	EPSD	ICGC;COSMIC	43.065	Down-regulation
TK_PDGFR_PDGFRB_Y	P16234	PDGFRA	P09619	PDGFRB	Y731	E726K	726	Missense	distal	-5	no	55.105	54.369	EPSD	ICGC	43.065	Down-regulation
TK_PDGFR_PDGFRB_Y	P16234	PDGFRA	P09619	PDGFRB	Y754	L761F	761	Missense	distal	7	no	64.177	64.231	PhosphoSitePlus	ICGC;COSMIC	43.065	Up-regulation
TK_PDGFR_PDGFRB_Y	P16234	PDGFRA	P09619	PDGFRB	Y754	D756N	756	Missense	proximal	2	no	64.177	56.882	PhosphoSitePlus	ICGC;COSMIC;CCLE	43.065	Down-regulation
TK_PDGFR_PDGFRB_Y	P16234	PDGFRA	P09619	PDGFRB	Y754	S755F	755	Missense	proximal	1	no	64.177	58.885	PhosphoSitePlus	ICGC;COSMIC	43.065	Down-regulation
TK_PDGFR_PDGFRB_Y	P16234	PDGFRA	P09619	PDGFRB	Y849	M844I	844	Missense	distal	-5	no	72.976	72.345	EPSD	ICGC;COSMIC	43.065	Down-regulation
TK_PDGFR_PDGFRB_Y	P16234	PDGFRA	P09619	PDGFRB	Y849	D842G	842	Missense	distal	-7	no	72.976	74.641	EPSD	ICGC	43.065	Up-regulation
TK_PDGFR_PDGFRB_Y	P16234	PDGFRA	P09619	PDGFRB	Y849	N848K	848	Missense	proximal	-1	no	72.976	68.122	EPSD	ICGC;COSMIC	43.065	Down-regulation
TK_PDGFR_PDGFRB_Y	P16234	PDGFRA	P09619	PDGFRB	Y849	Y849S	849	Missense	central	0	yes	72.976	0.000	EPSD	ICGC;COSMIC	43.065	Loss
TK_PDGFR_PDGFRB_Y	Q05397	PTK2	P09619	PDGFRB	Y5	D7G	7	Missense	proximal	2	no	52.065	41.143	PhosphoSitePlus;EPSD	ICGC;COSMIC	43.065	Loss
TK_PDGFR_PDGFRB_Y	Q05397	PTK2	P09619	PDGFRB	Y5	L6V	6	Missense	proximal	1	no	52.065	51.892	PhosphoSitePlus;EPSD	ICGC;COSMIC	43.065	Down-regulation
TK_PDGFR_PDGFRB_Y	Q05397	PTK2	P09619	PDGFRB	Y194	A187T	187	Missense	distal	-7	no	66.347	62.400	EPSD;PhosphoSitePlus	ICGC;COSMIC	43.065	Down-regulation
TK_PDGFR_PDGFRB_Y	Q05397	PTK2	P09619	PDGFRB	Y720	P723Q	723	Missense	distal	3	no	44.465	44.754	EPSD	ICGC	43.065	Up-regulation
TK_PDGFR_PDGFRB_Y	Q05397	PTK2	P09619	PDGFRB	Y720	E727K	727	Missense	distal	7	no	44.465	43.922	EPSD	ICGC;COSMIC	43.065	Down-regulation
TK_PDGFR_PDGFRB_Y	Q13769	THOC5	P09619	PDGFRB	Y225	I219T	219	Missense	distal	-6	no	69.391	73.083	PhosphoSitePlus	ICGC;COSMIC	43.065	Up-regulation
TK_PDGFR_PDGFRB_Y	P19174	PLCG1	P09619	PDGFRB	Y186	M180T	180	Missense	distal	-6	no	42.699	45.654	EPSD	ICGC;GDSC;CCLE	43.065	Gain
TK_PDGFR_PDGFRB_Y	P19174	PLCG1	P09619	PDGFRB	Y472	K465N	465	Missense	distal	-7	no	49.225	49.115	EPSD	ICGC	43.065	Down-regulation
TK_PDGFR_PDGFRB_Y	P19174	PLCG1	P09619	PDGFRB	Y977	G971C	971	Missense	distal	-6	no	51.813	54.664	EPSD	ICGC;COSMIC	43.065	Up-regulation
TK_PDGFR_PDGFRB_Y	P19174	PLCG1	P09619	PDGFRB	Y977	P984Q	984	Missense	distal	7	no	51.813	51.451	EPSD	ICGC;COSMIC	43.065	Down-regulation
TK_PDGFR_PDGFRB_Y	P19174	PLCG1	P09619	PDGFRB	Y991	E989Q	989	Missense	proximal	-2	no	43.594	43.859	EPSD	ICGC	43.065	Up-regulation
TK_PDGFR_PDGFRB_Y	P19174	PLCG1	P09619	PDGFRB	Y991	P984Q	984	Missense	distal	-7	no	43.594	41.773	EPSD	ICGC;COSMIC	43.065	Loss
TK_PDGFR_PDGFRB_Y	P19174	PLCG1	P09619	PDGFRB	Y1253	R1252H	1252	Missense	proximal	-1	no	44.142	40.316	EPSD	ICGC;COSMIC;CCLE	43.065	Loss
TK_PDGFR_PDGFRB_Y	P19174	PLCG1	P09619	PDGFRB	Y1253	Q1255K	1255	Missense	proximal	2	no	44.142	49.408	EPSD	ICGC;COSMIC	43.065	Up-regulation
TK_PDGFR_PDGFRB_Y	P06241	FYN	P09619	PDGFRB	Y28	Q24K	24	Missense	distal	-4	no	53.550	54.108	PhosphoSitePlus	ICGC	43.065	Up-regulation
TK_PDGFR_PDGFRB_Y	P06241	FYN	P09619	PDGFRB	Y28	S25R	25	Missense	distal	-3	no	53.550	45.736	PhosphoSitePlus	ICGC	43.065	Down-regulation
TK_PDGFR_PDGFRB_Y	Q07912	TNK2	P09619	PDGFRB	Y40	E44G	44	Missense	distal	4	no	48.546	48.615	EPSD	ICGC;COSMIC	43.065	Up-regulation
TK_PDGFR_PDGFRB_Y	Q07912	TNK2	P09619	PDGFRB	Y40	V41I	41	Missense	proximal	1	no	48.546	47.138	EPSD	ICGC;COSMIC	43.065	Down-regulation
TK_PDGFR_PDGFRB_Y	Q07912	TNK2	P09619	PDGFRB	Y40	H37N	37	Missense	distal	-3	no	48.546	54.141	EPSD	ICGC;COSMIC	43.065	Up-regulation
TK_PDGFR_PDGFRB_Y	Q07912	TNK2	P09619	PDGFRB	Y40	R34H	34	Missense	distal	-6	no	48.546	43.333	EPSD	ICGC;COSMIC	43.065	Down-regulation
TK_PDGFR_PDGFRB_Y	Q07912	TNK2	P09619	PDGFRB	Y635	P631A	631	Missense	distal	-4	no	67.743	65.370	PhosphoSitePlus	ICGC;COSMIC	43.065	Down-regulation
TK_PDGFR_PDGFRB_Y	Q07912	TNK2	P09619	PDGFRB	Y635	D636E	636	Missense	proximal	1	no	67.743	63.112	PhosphoSitePlus	ICGC	43.065	Down-regulation
TK_PDGFR_PDGFRB_Y	Q07912	TNK2	P09619	PDGFRB	Y635	A634S	634	Missense	proximal	-1	no	67.743	68.137	PhosphoSitePlus	ICGC;COSMIC	43.065	Up-regulation
TK_PDGFR_PDGFRB_Y	Q07912	TNK2	P09619	PDGFRB	Y635	P632L	632	Missense	distal	-3	no	67.743	58.840	PhosphoSitePlus	ICGC;COSMIC	43.065	Down-regulation
TK_PDGFR_PDGFRB_Y	Q07912	TNK2	P09619	PDGFRB	Y827	A828T	828	Missense	proximal	1	no	46.506	45.908	EPSD	ICGC;COSMIC	43.065	Down-regulation
TK_PDGFR_PDGFRB_Y	Q07912	TNK2	P09619	PDGFRB	Y827	A828P	828	Missense	proximal	1	no	46.506	44.811	EPSD	ICGC;COSMIC	43.065	Down-regulation
TK_PDGFR_PDGFRB_Y	Q07912	TNK2	P09619	PDGFRB	Y827	Q831K	831	Missense	distal	4	no	46.506	45.989	EPSD	ICGC;COSMIC	43.065	Down-regulation
TK_PDGFR_PDGFRB_Y	P12931	SRC	P09619	PDGFRB	Y419	G424C	424	Missense	distal	5	no	73.742	67.304	PhosphoSitePlus	ICGC;COSMIC	43.065	Down-regulation
TK_PDGFR_PDGFRB_Y	P12931	SRC	P09619	PDGFRB	Y419	R422W	422	Missense	distal	3	no	73.742	73.818	PhosphoSitePlus	ICGC	43.065	Up-regulation
TK_FGFR_FGFR4_Y	P22455	FGFR4	P22455	FGFR4	Y390	G388R	388	Missense	proximal	-2	no	1.625	1.627	EPSD	ICGC;COSMIC	1.608	Up-regulation
TK_FGFR_FGFR4_Y	P22455	FGFR4	P22455	FGFR4	Y390	G392E	392	Missense	proximal	2	no	1.625	1.898	EPSD	ICGC;COSMIC	1.608	Up-regulation
TK_FGFR_FGFR4_Y	P22455	FGFR4	P22455	FGFR4	Y754	S751F	751	Missense	distal	-3	no	4.451	4.476	PhosphoSitePlus	ICGC;COSMIC	1.608	Up-regulation
CMGC_CDK_CDK7_CDK7_ST	P21127	CDK11B	P50613	CDK7	S38	R45W	45	Missense	distal	7	no	14.733	15.696	EPSD	ICGC	13.598	Up-regulation
CMGC_CDK_CDK7_CDK7_ST	P21127	CDK11B	P50613	CDK7	S65	S72Y	72	Missense	distal	7	no	12.575	13.824	EPSD	ICGC;COSMIC	13.598	Gain
CMGC_CDK_CDK7_CDK7_ST	P21127	CDK11B	P50613	CDK7	S398	G392V	392	Missense	distal	-6	no	17.481	17.793	EPSD	ICGC;COSMIC	13.598	Up-regulation
CMGC_CDK_CDK7_CDK7_ST	P49736	MCM2	P50613	CDK7	S5	A11S	11	Missense	distal	6	no	15.526	13.847	PhosphoSitePlus;EPSD	ICGC	13.598	Down-regulation
CMGC_CDK_CDK7_CDK7_ST	P49736	MCM2	P50613	CDK7	S13	R18P	18	Missense	distal	5	no	15.751	17.413	EPSD;PhosphoSitePlus	ICGC;GDSC	13.598	Up-regulation
CMGC_CDK_CDK7_CDK7_ST	P49736	MCM2	P50613	CDK7	S13	A11S	11	Missense	proximal	-2	no	15.751	15.949	EPSD;PhosphoSitePlus	ICGC	13.598	Up-regulation
CMGC_CDK_CDK7_CDK7_ST	P49736	MCM2	P50613	CDK7	S27	R33Q	33	Missense	distal	6	no	18.849	17.954	EPSD;PhosphoSitePlus	ICGC	13.598	Down-regulation
CMGC_CDK_CDK7_CDK7_ST	P49736	MCM2	P50613	CDK7	S40	R33Q	33	Missense	distal	-7	no	22.651	21.464	EPSD;PhosphoSitePlus	ICGC	13.598	Down-regulation
CMGC_CDK_CDK7_CDK7_ST	P49736	MCM2	P50613	CDK7	S40	S40P	40	Missense	central	0	yes	22.651	0.000	EPSD;PhosphoSitePlus	ICGC;COSMIC	13.598	Loss
CMGC_CDK_CDK7_CDK7_ST	P49736	MCM2	P50613	CDK7	S41	S40P	40	Missense	proximal	-1	no	22.804	22.550	EPSD;PhosphoSitePlus	ICGC;COSMIC	13.598	Down-regulation
CMGC_CDK_CDK7_CDK7_ST	P49736	MCM2	P50613	CDK7	S53	G58V	58	Missense	distal	5	no	21.071	19.847	EPSD;PhosphoSitePlus	ICGC;COSMIC	13.598	Down-regulation
CMGC_CDK_CDK7_CDK7_ST	P49736	MCM2	P50613	CDK7	S53	D51Y	51	Missense	proximal	-2	no	21.071	21.504	EPSD;PhosphoSitePlus	ICGC;COSMIC	13.598	Up-regulation
CMGC_CDK_CDK7_CDK7_ST	P49736	MCM2	P50613	CDK7	S53	S53F	53	Missense	central	0	yes	21.071	0.000	EPSD;PhosphoSitePlus	ICGC	13.598	Loss
CMGC_CDK_CDK7_CDK7_ST	P49736	MCM2	P50613	CDK7	T59	G58V	58	Missense	proximal	-1	no	23.482	23.749	EPSD;PhosphoSitePlus	ICGC;COSMIC	13.598	Up-regulation
CMGC_CDK_CDK7_CDK7_ST	P49736	MCM2	P50613	CDK7	T59	L63M	63	Missense	distal	4	no	23.482	24.468	EPSD;PhosphoSitePlus	ICGC;COSMIC	13.598	Up-regulation
CMGC_CDK_CDK7_CDK7_ST	P49736	MCM2	P50613	CDK7	T59	S53F	53	Missense	distal	-6	no	23.482	23.066	EPSD;PhosphoSitePlus	ICGC	13.598	Down-regulation
CMGC_CDK_CDK7_CDK7_ST	P49736	MCM2	P50613	CDK7	S108	A107S	107	Missense	proximal	-1	no	26.698	26.757	EPSD;PhosphoSitePlus	ICGC	13.598	Up-regulation
CMGC_CDK_CDK7_CDK7_ST	P49736	MCM2	P50613	CDK7	S108	R115Q	115	Missense	distal	7	no	26.698	26.127	EPSD;PhosphoSitePlus	ICGC;COSMIC	13.598	Down-regulation
CMGC_CDK_CDK7_CDK7_ST	P49736	MCM2	P50613	CDK7	S139	E145D	145	Missense	distal	6	no	21.705	19.859	EPSD;PhosphoSitePlus	ICGC;COSMIC	13.598	Down-regulation
CMGC_CDK_CDK7_CDK7_ST	P49736	MCM2	P50613	CDK7	S139	R132C	132	Missense	distal	-7	no	21.705	20.666	EPSD;PhosphoSitePlus	ICGC;COSMIC;CCLE	13.598	Down-regulation
CMGC_CDK_CDK7_CDK7_ST	P49736	MCM2	P50613	CDK7	S381	R375C	375	Missense	distal	-6	no	17.069	16.695	EPSD	ICGC;COSMIC;GDSC;CCLE	13.598	Down-regulation
CMGC_CDK_CDK7_CDK7_ST	P49736	MCM2	P50613	CDK7	S381	A386V	386	Missense	distal	5	no	17.069	15.028	EPSD	ICGC;COSMIC	13.598	Down-regulation
CMGC_CDK_CDK7_CDK7_ST	P49736	MCM2	P50613	CDK7	S381	R377Q	377	Missense	distal	-4	no	17.069	17.035	EPSD	ICGC;COSMIC	13.598	Down-regulation
CMGC_CDK_CDK7_CDK7_ST	P49736	MCM2	P50613	CDK7	T598	D594Y	594	Missense	distal	-4	no	18.631	18.452	EPSD	ICGC	13.598	Down-regulation
CMGC_CDK_CDK7_CDK7_ST	P49736	MCM2	P50613	CDK7	S813	R815C	815	Missense	proximal	2	no	17.979	16.536	EPSD	ICGC;COSMIC	13.598	Down-regulation
CMGC_CDK_CDK7_CDK7_ST	P49736	MCM2	P50613	CDK7	S813	V810A	810	Missense	distal	-3	no	17.979	20.989	EPSD	ICGC	13.598	Up-regulation
CMGC_CDK_CDK7_CDK7_ST	P49736	MCM2	P50613	CDK7	S813	R820L	820	Missense	distal	7	no	17.979	14.386	EPSD	ICGC	13.598	Down-regulation
CMGC_CDK_CDK7_CDK7_ST	P49736	MCM2	P50613	CDK7	S813	F818S	818	Missense	distal	5	no	17.979	20.184	EPSD	ICGC	13.598	Up-regulation
CMGC_CDK_CDK7_CDK7_ST	P24941	CDK2	P50613	CDK7	T41	D38V	38	Missense	distal	-3	no	14.399	15.783	EPSD	ICGC;COSMIC	13.598	Up-regulation
CMGC_CDK_CDK7_CDK7_ST	P24941	CDK2	P50613	CDK7	T41	T39M	39	Missense	proximal	-2	no	14.399	14.287	EPSD	ICGC	13.598	Down-regulation
CMGC_CDK_CDK7_CDK7_ST	P24941	CDK2	P50613	CDK7	S46	T39M	39	Missense	distal	-7	no	21.025	19.933	EPSD;PhosphoSitePlus	ICGC	13.598	Down-regulation
CMGC_CDK_CDK7_CDK7_ST	P24941	CDK2	P50613	CDK7	T160	R157W	157	Missense	distal	-3	no	33.784	27.795	EPSD;PhosphoSitePlus	ICGC;COSMIC	13.598	Down-regulation
CMGC_CDK_CDK7_CDK7_ST	P24941	CDK2	P50613	CDK7	T160	R157L	157	Missense	distal	-3	no	33.784	30.836	EPSD;PhosphoSitePlus	ICGC;COSMIC	13.598	Down-regulation
CMGC_CDK_CDK7_CDK7_ST	P24941	CDK2	P50613	CDK7	S207	R200Q	200	Missense	distal	-7	no	14.875	13.688	EPSD	ICGC;COSMIC	13.598	Down-regulation
CMGC_CDK_CDK7_CDK7_ST	P03372	ESR1	P50613	CDK7	S102	P99S	99	Missense	distal	-3	no	15.152	14.743	EPSD	ICGC	13.598	Down-regulation
CMGC_CDK_CDK7_CDK7_ST	P03372	ESR1	P50613	CDK7	S102	G95W	95	Missense	distal	-7	no	15.152	16.007	EPSD	ICGC	13.598	Up-regulation
CMGC_CDK_CDK7_CDK7_ST	P03372	ESR1	P50613	CDK7	S102	S102N	102	Missense	central	0	yes	15.152	0.000	EPSD	ICGC;COSMIC	13.598	Loss
CMGC_CDK_CDK7_CDK7_ST	P03372	ESR1	P50613	CDK7	S102	N101S	101	Missense	proximal	-1	no	15.152	15.153	EPSD	ICGC;COSMIC	13.598	Up-regulation
CMGC_CDK_CDK7_CDK7_ST	P03372	ESR1	P50613	CDK7	S106	P99S	99	Missense	distal	-7	no	17.012	14.935	EPSD	ICGC	13.598	Down-regulation
CMGC_CDK_CDK7_CDK7_ST	P03372	ESR1	P50613	CDK7	S106	S102N	102	Missense	distal	-4	no	17.012	17.499	EPSD	ICGC;COSMIC	13.598	Up-regulation
CMGC_CDK_CDK7_CDK7_ST	P03372	ESR1	P50613	CDK7	S106	N101S	101	Missense	distal	-5	no	17.012	19.869	EPSD	ICGC;COSMIC	13.598	Up-regulation
CMGC_CDK_CDK7_CDK7_ST	P03372	ESR1	P50613	CDK7	S106	H112P	112	Missense	distal	6	no	17.012	16.741	EPSD	ICGC;COSMIC	13.598	Down-regulation
CMGC_CDK_CDK7_CDK7_ST	P03372	ESR1	P50613	CDK7	S118	H112P	112	Missense	distal	-6	no	23.487	24.252	PhosphoSitePlus	ICGC;COSMIC	13.598	Up-regulation
CMGC_CDK_CDK7_CDK7_ST	P03372	ESR1	P50613	CDK7	S118	P114L	114	Missense	distal	-4	no	23.487	23.520	PhosphoSitePlus	ICGC;COSMIC	13.598	Up-regulation
CMGC_CDK_CDK7_CDK7_ST	P03372	ESR1	P50613	CDK7	T574	S576L	576	Missense	proximal	2	no	19.161	19.242	EPSD	ICGC;COSMIC	13.598	Up-regulation
CMGC_CDK_CDK7_CDK7_ST	P03372	ESR1	P50613	CDK7	S575	S576L	576	Missense	proximal	1	no	15.227	16.289	EPSD	ICGC;COSMIC	13.598	Up-regulation
CMGC_CDK_CDK7_CDK7_ST	Q00534	CDK6	P50613	CDK7	T177	S171G	171	Missense	distal	-6	no	29.096	28.304	PhosphoSitePlus	ICGC;COSMIC	13.598	Down-regulation
CMGC_CDK_CDK7_CDK7_ST	Q00534	CDK6	P50613	CDK7	S317	P316S	316	Missense	proximal	-1	no	14.253	14.507	EPSD	ICGC;COSMIC	13.598	Up-regulation
CMGC_CDK_CDK7_CDK7_ST	P04637	TP53	P50613	CDK7	S33	P34L	34	Missense	proximal	1	no	20.872	13.401	EPSD;PhosphoSitePlus	ICGC;COSMIC	13.598	Loss
CMGC_CDK_CDK7_CDK7_ST	P04637	TP53	P50613	CDK7	S33	S33F	33	Missense	central	0	yes	20.872	0.000	EPSD;PhosphoSitePlus	ICGC;COSMIC	13.598	Loss
CMGC_CDK_CDK7_CDK7_ST	P04637	TP53	P50613	CDK7	S33	N30I	30	Missense	distal	-3	no	20.872	21.821	EPSD;PhosphoSitePlus	ICGC	13.598	Up-regulation
CMGC_CDK_CDK7_CDK7_ST	P04637	TP53	P50613	CDK7	S46	D48G	48	Missense	proximal	2	no	15.372	14.587	EPSD	ICGC;COSMIC	13.598	Down-regulation
CMGC_CDK_CDK7_CDK7_ST	P04637	TP53	P50613	CDK7	S46	Q52K	52	Missense	distal	6	no	15.372	15.165	EPSD	ICGC	13.598	Down-regulation
CMGC_CDK_CDK7_CDK7_ST	P04637	TP53	P50613	CDK7	T81	A88D	88	Missense	distal	7	no	16.811	14.277	EPSD	ICGC	13.598	Down-regulation
CMGC_CDK_CDK7_CDK7_ST	P04637	TP53	P50613	CDK7	T81	P87Q	87	Missense	distal	6	no	16.811	16.861	EPSD	ICGC;COSMIC	13.598	Up-regulation
CMGC_CDK_CDK7_CDK7_ST	P04637	TP53	P50613	CDK7	S127	T125R	125	Missense	proximal	-2	no	17.259	17.218	EPSD	ICGC;COSMIC	13.598	Down-regulation
CMGC_CDK_CDK7_CDK7_ST	P04637	TP53	P50613	CDK7	S127	F134C	134	Missense	distal	7	no	17.259	15.100	EPSD	ICGC;COSMIC;CCLE	13.598	Down-regulation
CMGC_CDK_CDK7_CDK7_ST	P04637	TP53	P50613	CDK7	S127	C124G	124	Missense	distal	-3	no	17.259	16.252	EPSD	ICGC;COSMIC	13.598	Down-regulation
CMGC_CDK_CDK7_CDK7_ST	P04637	TP53	P50613	CDK7	S127	C124R	124	Missense	distal	-3	no	17.259	21.327	EPSD	ICGC;COSMIC;GDSC;CCLE	13.598	Up-regulation
CMGC_CDK_CDK7_CDK7_ST	P04637	TP53	P50613	CDK7	S127	L130H	130	Missense	distal	3	no	17.259	17.380	EPSD	ICGC;COSMIC	13.598	Up-regulation
CMGC_CDK_CDK7_CDK7_ST	P04637	TP53	P50613	CDK7	S127	T125A	125	Missense	proximal	-2	no	17.259	17.552	EPSD	ICGC;COSMIC	13.598	Up-regulation
CMGC_CDK_CDK7_CDK7_ST	P04637	TP53	P50613	CDK7	S127	K120N	120	Missense	distal	-7	no	17.259	14.731	EPSD	ICGC;COSMIC;GDSC;CCLE	13.598	Down-regulation
CMGC_CDK_CDK7_CDK7_ST	P04637	TP53	P50613	CDK7	S127	N131Y	131	Missense	distal	4	no	17.259	16.943	EPSD	ICGC;COSMIC	13.598	Down-regulation
CMGC_CDK_CDK7_CDK7_ST	P04637	TP53	P50613	CDK7	S127	K120M	120	Missense	distal	-7	no	17.259	13.912	EPSD	ICGC;COSMIC	13.598	Down-regulation
CMGC_CDK_CDK7_CDK7_ST	P04637	TP53	P50613	CDK7	S127	K132M	132	Missense	distal	5	no	17.259	17.088	EPSD	ICGC;COSMIC;CCLE	13.598	Down-regulation
CMGC_CDK_CDK7_CDK7_ST	P04637	TP53	P50613	CDK7	S127	M133T	133	Missense	distal	6	no	17.259	16.079	EPSD	ICGC;COSMIC	13.598	Down-regulation
CMGC_CDK_CDK7_CDK7_ST	P04637	TP53	P50613	CDK7	S127	K120R	120	Missense	distal	-7	no	17.259	15.630	EPSD	ICGC;COSMIC	13.598	Down-regulation
CMGC_CDK_CDK7_CDK7_ST	P04637	TP53	P50613	CDK7	S127	C124Y	124	Missense	distal	-3	no	17.259	18.116	EPSD	ICGC;COSMIC	13.598	Up-regulation
CMGC_CDK_CDK7_CDK7_ST	P04637	TP53	P50613	CDK7	T155	R156L	156	Missense	proximal	1	no	12.335	14.443	EPSD	ICGC;COSMIC	13.598	Gain
CMGC_CDK_CDK7_CDK7_ST	P04637	TP53	P50613	CDK7	T155	P152R	152	Missense	distal	-3	no	12.335	15.322	EPSD	ICGC;COSMIC	13.598	Gain
CMGC_CDK_CDK7_CDK7_ST	P04637	TP53	P50613	CDK7	S315	T312I	312	Missense	distal	-3	no	14.594	13.514	EPSD	ICGC;COSMIC	13.598	Loss
CMGC_CDK_CDK7_CDK7_ST	P04637	TP53	P50613	CDK7	S315	P322T	322	Missense	distal	7	no	14.594	11.275	EPSD	ICGC	13.598	Loss
CMGC_CDK_CDK7_CDK7_ST	P04637	TP53	P50613	CDK7	S371	T377P	377	Missense	distal	6	no	20.263	20.660	PhosphoSitePlus;EPSD	ICGC;COSMIC	13.598	Up-regulation
CMGC_CDK_CDK7_CDK7_ST	P04637	TP53	P50613	CDK7	S371	G374C	374	Missense	distal	3	no	20.263	20.808	PhosphoSitePlus;EPSD	ICGC;COSMIC	13.598	Up-regulation
CMGC_CDK_CDK7_CDK7_ST	P04637	TP53	P50613	CDK7	S376	T377P	377	Missense	proximal	1	no	20.595	27.756	EPSD;PhosphoSitePlus	ICGC;COSMIC	13.598	Up-regulation
CMGC_CDK_CDK7_CDK7_ST	P04637	TP53	P50613	CDK7	S376	G374C	374	Missense	proximal	-2	no	20.595	20.377	EPSD;PhosphoSitePlus	ICGC;COSMIC	13.598	Down-regulation
CMGC_CDK_CDK7_CDK7_ST	P04637	TP53	P50613	CDK7	S376	R379S	379	Missense	distal	3	no	20.595	19.894	EPSD;PhosphoSitePlus	ICGC	13.598	Down-regulation
CMGC_CDK_CDK7_CDK7_ST	P04637	TP53	P50613	CDK7	S376	R379C	379	Missense	distal	3	no	20.595	20.389	EPSD;PhosphoSitePlus	ICGC;COSMIC	13.598	Down-regulation
CMGC_CDK_CDK7_CDK7_ST	P04637	TP53	P50613	CDK7	S378	T377P	377	Missense	proximal	-1	no	19.642	19.634	EPSD;PhosphoSitePlus	ICGC;COSMIC	13.598	Down-regulation
CMGC_CDK_CDK7_CDK7_ST	P04637	TP53	P50613	CDK7	S378	F385L	385	Missense	distal	7	no	19.642	15.075	EPSD;PhosphoSitePlus	ICGC;COSMIC	13.598	Down-regulation
CMGC_CDK_CDK7_CDK7_ST	P04637	TP53	P50613	CDK7	S378	G374C	374	Missense	distal	-4	no	19.642	18.829	EPSD;PhosphoSitePlus	ICGC;COSMIC	13.598	Down-regulation
CMGC_CDK_CDK7_CDK7_ST	P04637	TP53	P50613	CDK7	S378	R379S	379	Missense	proximal	1	no	19.642	20.688	EPSD;PhosphoSitePlus	ICGC	13.598	Up-regulation
CMGC_CDK_CDK7_CDK7_ST	P04637	TP53	P50613	CDK7	S378	R379C	379	Missense	proximal	1	no	19.642	19.498	EPSD;PhosphoSitePlus	ICGC;COSMIC	13.598	Down-regulation
CMGC_CDK_CDK7_CDK7_ST	O00267	SUPT5H	P50613	CDK7	S36	E37G	37	Missense	proximal	1	no	13.744	3.176	EPSD	ICGC;COSMIC	13.598	Loss
CMGC_CDK_CDK7_CDK7_ST	O00267	SUPT5H	P50613	CDK7	S36	R30Q	30	Missense	distal	-6	no	13.744	13.493	EPSD	ICGC;COSMIC	13.598	Loss
CMGC_CDK_CDK7_CDK7_ST	O00267	SUPT5H	P50613	CDK7	S36	S36N	36	Missense	central	0	yes	13.744	0.000	EPSD	ICGC;COSMIC	13.598	Loss
CMGC_CDK_CDK7_CDK7_ST	O00267	SUPT5H	P50613	CDK7	S36	P42T	42	Missense	distal	6	no	13.744	13.347	EPSD	ICGC;COSMIC	13.598	Loss
CMGC_CDK_CDK7_CDK7_ST	O00267	SUPT5H	P50613	CDK7	S686	G692C	692	Missense	distal	6	no	14.289	15.291	EPSD	ICGC	13.598	Up-regulation
CMGC_CDK_CDK7_CDK7_ST	O00267	SUPT5H	P50613	CDK7	S686	G690S	690	Missense	distal	4	no	14.289	14.086	EPSD	ICGC	13.598	Down-regulation
CMGC_CDK_CDK7_CDK7_ST	O00267	SUPT5H	P50613	CDK7	S686	P687T	687	Missense	proximal	1	no	14.289	7.128	EPSD	ICGC;COSMIC	13.598	Loss
CMGC_CDK_CDK7_CDK7_ST	O00267	SUPT5H	P50613	CDK7	S763	S763A	763	Missense	central	0	yes	23.713	0.000	EPSD	ICGC;COSMIC	13.598	Loss
CMGC_CDK_CDK7_CDK7_ST	O00267	SUPT5H	P50613	CDK7	S763	G760S	760	Missense	distal	-3	no	23.713	25.392	EPSD	ICGC;COSMIC	13.598	Up-regulation
CMGC_CDK_CDK7_CDK7_ST	O00267	SUPT5H	P50613	CDK7	S763	M761I	761	Missense	proximal	-2	no	23.713	24.090	EPSD	ICGC;GDSC;CCLE	13.598	Up-regulation
CMGC_CDK_CDK7_CDK7_ST	O00267	SUPT5H	P50613	CDK7	T806	T806M	806	Missense	central	0	yes	16.696	0.000	EPSD	ICGC	13.598	Loss
CMGC_CDK_CDK7_CDK7_ST	O00267	SUPT5H	P50613	CDK7	T806	G803D	803	Missense	distal	-3	no	16.696	15.932	EPSD	ICGC	13.598	Down-regulation
CMGC_CDK_CDK7_CDK7_ST	O00267	SUPT5H	P50613	CDK7	S812	T814I	814	Missense	proximal	2	no	14.513	15.331	EPSD	ICGC;COSMIC	13.598	Up-regulation
CMGC_CDK_CDK7_CDK7_ST	O00267	SUPT5H	P50613	CDK7	S812	T806M	806	Missense	distal	-6	no	14.513	14.348	EPSD	ICGC	13.598	Down-regulation
CMGC_CDK_CDK7_CDK7_ST	O00267	SUPT5H	P50613	CDK7	S812	P815F	815	Missense	distal	3	no	14.513	14.421	EPSD	ICGC	13.598	Down-regulation
CMGC_CDK_CDK7_CDK7_ST	O00267	SUPT5H	P50613	CDK7	T814	T814I	814	Missense	central	0	yes	14.065	0.000	EPSD	ICGC;COSMIC	13.598	Loss
CMGC_CDK_CDK7_CDK7_ST	O00267	SUPT5H	P50613	CDK7	T814	P815F	815	Missense	proximal	1	no	14.065	8.180	EPSD	ICGC	13.598	Loss
CMGC_CDK_CDK7_CDK7_ST	O00267	SUPT5H	P50613	CDK7	T828	P829L	829	Missense	proximal	1	no	20.944	13.473	EPSD	ICGC	13.598	Loss
CMGC_CDK_CDK7_CDK7_ST	O00267	SUPT5H	P50613	CDK7	T828	P823H	823	Missense	distal	-5	no	20.944	17.526	EPSD	ICGC;COSMIC	13.598	Down-regulation
CMGC_CDK_CDK7_CDK7_ST	O00267	SUPT5H	P50613	CDK7	T854	P857H	857	Missense	distal	3	no	26.610	25.722	EPSD	ICGC;COSMIC	13.598	Down-regulation
CMGC_CDK_CDK7_CDK7_ST	O00267	SUPT5H	P50613	CDK7	S866	S867P	867	Missense	proximal	1	no	6.131	14.664	EPSD	ICGC;COSMIC	13.598	Gain
CMGC_CDK_CDK7_CDK7_ST	O00267	SUPT5H	P50613	CDK7	S867	S867P	867	Missense	central	0	yes	20.493	0.000	EPSD	ICGC;COSMIC	13.598	Loss
CMGC_CDK_CDK7_CDK7_ST	O00267	SUPT5H	P50613	CDK7	S867	P865H	865	Missense	proximal	-2	no	20.493	20.039	EPSD	ICGC;COSMIC	13.598	Down-regulation
CMGC_CDK_CDK7_CDK7_ST	O00267	SUPT5H	P50613	CDK7	S897	P904A	904	Missense	distal	7	no	15.862	14.649	EPSD	ICGC;COSMIC	13.598	Down-regulation
CMGC_CDK_CDK7_CDK7_ST	O00267	SUPT5H	P50613	CDK7	S897	P898T	898	Missense	proximal	1	no	15.862	8.701	EPSD	ICGC;COSMIC	13.598	Loss
CMGC_CDK_CDK7_CDK7_ST	O00267	SUPT5H	P50613	CDK7	S951	M953V	953	Missense	proximal	2	no	15.110	15.526	EPSD	ICGC	13.598	Up-regulation
CMGC_CDK_CDK7_CDK7_ST	O00267	SUPT5H	P50613	CDK7	S951	S946G	946	Missense	distal	-5	no	15.110	12.429	EPSD	ICGC	13.598	Loss
CMGC_CDK_CDK7_CDK7_ST	P50750	CDK9	P50613	CDK7	S175	P182S	182	Missense	distal	7	no	21.983	17.056	PhosphoSitePlus	ICGC;COSMIC	13.598	Down-regulation
CMGC_CDK_CDK7_CDK7_ST	P50750	CDK9	P50613	CDK7	S175	F168Y	168	Missense	distal	-7	no	21.983	21.518	PhosphoSitePlus	ICGC	13.598	Down-regulation
CMGC_CDK_CDK7_CDK7_ST	P50750	CDK9	P50613	CDK7	S180	P182S	182	Missense	proximal	2	no	14.463	13.966	EPSD	ICGC;COSMIC	13.598	Down-regulation
CMGC_CDK_CDK7_CDK7_ST	P50750	CDK9	P50613	CDK7	S180	N183K	183	Missense	distal	3	no	14.463	14.570	EPSD	ICGC;COSMIC	13.598	Up-regulation
CMGC_CDK_CDK7_CDK7_ST	P50750	CDK9	P50613	CDK7	S180	R184H	184	Missense	distal	4	no	14.463	12.418	EPSD	ICGC	13.598	Loss
CMGC_CDK_CDK7_CDK7_ST	P50750	CDK9	P50613	CDK7	T186	P182S	182	Missense	distal	-4	no	18.718	18.523	EPSD	ICGC;COSMIC	13.598	Down-regulation
CMGC_CDK_CDK7_CDK7_ST	P50750	CDK9	P50613	CDK7	T186	N183K	183	Missense	distal	-3	no	18.718	20.655	EPSD	ICGC;COSMIC	13.598	Up-regulation
CMGC_CDK_CDK7_CDK7_ST	P50750	CDK9	P50613	CDK7	T186	R184H	184	Missense	proximal	-2	no	18.718	18.474	EPSD	ICGC	13.598	Down-regulation
CMGC_CDK_CDK7_CDK7_ST	P50750	CDK9	P50613	CDK7	T362	N355S	355	Missense	distal	-7	no	15.027	13.819	EPSD	ICGC	13.598	Down-regulation
CMGC_CDK_CDK7_CDK7_ST	P24928	POLR2A	P50613	CDK7	S217	E223A	223	Missense	distal	6	no	15.595	16.192	EPSD	ICGC	13.598	Up-regulation
CMGC_CDK_CDK7_CDK7_ST	P24928	POLR2A	P50613	CDK7	S1348	V1355I	1355	Missense	distal	7	no	12.738	14.591	EPSD	ICGC	13.598	Gain
CMGC_CDK_CDK7_CDK7_ST	P24928	POLR2A	P50613	CDK7	S1571	W1565C	1565	Missense	distal	-6	no	14.917	15.548	EPSD	ICGC	13.598	Up-regulation
CMGC_CDK_CDK7_CDK7_ST	P24928	POLR2A	P50613	CDK7	S1571	G1570D	1570	Missense	proximal	-1	no	14.917	15.098	EPSD	ICGC	13.598	Up-regulation
CMGC_CDK_CDK7_CDK7_ST	P24928	POLR2A	P50613	CDK7	S1619	T1625P	1625	Missense	distal	6	no	22.614	23.011	EPSD;PhosphoSitePlus	ICGC	13.598	Up-regulation
CMGC_CDK_CDK7_CDK7_ST	P24928	POLR2A	P50613	CDK7	S1621	T1625P	1625	Missense	distal	4	no	20.619	22.384	EPSD;PhosphoSitePlus	ICGC	13.598	Up-regulation
CMGC_CDK_CDK7_CDK7_ST	P24928	POLR2A	P50613	CDK7	S1626	T1625P	1625	Missense	proximal	-1	no	14.394	14.386	EPSD	ICGC	13.598	Down-regulation
CMGC_CDK_CDK7_CDK7_ST	P24928	POLR2A	P50613	CDK7	S1647	S1644L	1644	Missense	distal	-3	no	14.995	15.443	EPSD	ICGC	13.598	Up-regulation
CMGC_CDK_CDK7_CDK7_ST	P24928	POLR2A	P50613	CDK7	S1661	S1665P	1665	Missense	distal	4	no	14.361	16.510	EPSD	ICGC	13.598	Up-regulation
CMGC_CDK_CDK7_CDK7_ST	P24928	POLR2A	P50613	CDK7	S1668	S1665P	1665	Missense	distal	-3	no	14.197	14.606	EPSD	ICGC	13.598	Up-regulation
CMGC_CDK_CDK7_CDK7_ST	P24928	POLR2A	P50613	CDK7	S1829	A1835T	1835	Missense	distal	6	no	16.055	14.346	EPSD	ICGC	13.598	Down-regulation
CMGC_CDK_CDK7_CDK7_ST	P24928	POLR2A	P50613	CDK7	S1833	A1835T	1835	Missense	proximal	2	no	13.422	14.149	EPSD	ICGC	13.598	Gain
CMGC_CDK_CDK7_CDK7_ST	P24928	POLR2A	P50613	CDK7	T1840	A1835T	1835	Missense	distal	-5	no	14.722	15.478	EPSD	ICGC	13.598	Up-regulation
CMGC_CDK_CDK7_CDK7_ST	P24928	POLR2A	P50613	CDK7	S1845	S1850C	1850	Missense	distal	5	no	17.154	15.678	EPSD	ICGC	13.598	Down-regulation
CMGC_CDK_CDK7_CDK7_ST	P24928	POLR2A	P50613	CDK7	S1847	T1854P	1854	Missense	distal	7	no	11.684	15.003	EPSD	ICGC	13.598	Gain
CMGC_CDK_CDK7_CDK7_ST	P24928	POLR2A	P50613	CDK7	S1857	S1850C	1850	Missense	distal	-7	no	12.720	13.789	EPSD	ICGC	13.598	Gain
CMGC_CDK_CDK7_CDK7_ST	P24928	POLR2A	P50613	CDK7	S1864	S1861L	1861	Missense	distal	-3	no	13.507	13.956	EPSD	ICGC	13.598	Gain
CMGC_CDK_CDK7_CDK7_ST	P24928	POLR2A	P50613	CDK7	S1868	S1861L	1861	Missense	distal	-7	no	10.969	13.882	EPSD	ICGC	13.598	Gain
CMGC_CDK_CDK7_CDK7_ST	P24928	POLR2A	P50613	CDK7	T1885	P1890S	1890	Missense	distal	5	no	17.206	18.591	EPSD	ICGC	13.598	Up-regulation
CMGC_CDK_CDK7_CDK7_ST	P24928	POLR2A	P50613	CDK7	T1894	P1890S	1890	Missense	distal	-4	no	15.598	15.403	EPSD	ICGC	13.598	Down-regulation
CMGC_CDK_CDK7_CDK7_ST	P24928	POLR2A	P50613	CDK7	S1913	S1920F	1920	Missense	distal	7	no	13.635	18.456	EPSD	ICGC	13.598	Up-regulation
CMGC_CDK_CDK7_CDK7_ST	P24928	POLR2A	P50613	CDK7	T1939	S1938P	1938	Missense	proximal	-1	no	19.787	19.534	EPSD	ICGC	13.598	Down-regulation
CMGC_CDK_CDK7_CDK7_ST	P24928	POLR2A	P50613	CDK7	S1941	S1938P	1938	Missense	distal	-3	no	17.772	18.181	EPSD	ICGC	13.598	Up-regulation
CMGC_CDK_CDK7_CDK7_ST	P24928	POLR2A	P50613	CDK7	S1944	S1938P	1938	Missense	distal	-6	no	15.729	15.330	EPSD	ICGC	13.598	Down-regulation
CMGC_CDK_CDK7_CDK7_ST	P24928	POLR2A	P50613	CDK7	S1948	P1952H	1952	Missense	distal	4	no	15.454	13.861	EPSD	ICGC	13.598	Down-regulation
CMGC_CDK_CDK7_CDK7_ST	P24928	POLR2A	P50613	CDK7	S1962	P1963L	1963	Missense	proximal	1	no	20.322	12.851	EPSD	ICGC	13.598	Loss
CMGC_CDK_CDK7_CDK7_ST	Q9H0D6	XRN2	P50613	CDK7	S16	R12L	12	Missense	distal	-4	no	20.912	20.992	EPSD	ICGC	13.598	Up-regulation
CMGC_CDK_CDK7_CDK7_ST	Q01094	E2F1	P50613	CDK7	T96	E103D	103	Missense	distal	7	no	18.866	16.174	EPSD	ICGC;COSMIC	13.598	Down-regulation
CMGC_CDK_CDK7_CDK7_ST	Q01094	E2F1	P50613	CDK7	T96	L94M	94	Missense	proximal	-2	no	18.866	18.368	EPSD	ICGC	13.598	Down-regulation
CMGC_CDK_CDK7_CDK7_ST	Q01094	E2F1	P50613	CDK7	T96	D97E	97	Missense	proximal	1	no	18.866	23.476	EPSD	ICGC	13.598	Up-regulation
CMGC_CDK_CDK7_CDK7_ST	Q01094	E2F1	P50613	CDK7	T96	R90W	90	Missense	distal	-6	no	18.866	17.860	EPSD	ICGC	13.598	Down-regulation
CMGC_CDK_CDK7_CDK7_ST	Q01094	E2F1	P50613	CDK7	T135	R138H	138	Missense	distal	3	no	19.767	18.926	EPSD	ICGC;COSMIC	13.598	Down-regulation
CMGC_CDK_CDK7_CDK7_ST	Q01094	E2F1	P50613	CDK7	T135	L142M	142	Missense	distal	7	no	19.767	23.972	EPSD	ICGC	13.598	Up-regulation
CMGC_CDK_CDK7_CDK7_ST	Q01094	E2F1	P50613	CDK7	T311	S318A	318	Missense	distal	7	no	10.525	14.238	EPSD	ICGC	13.598	Gain
CMGC_CDK_CDK7_CDK7_ST	Q01094	E2F1	P50613	CDK7	S313	P308T	308	Missense	distal	-5	no	13.787	12.641	EPSD	ICGC	13.598	Loss
CMGC_CDK_CDK7_CDK7_ST	Q01094	E2F1	P50613	CDK7	S313	S318A	318	Missense	distal	5	no	13.787	13.144	EPSD	ICGC	13.598	Loss
CMGC_CDK_CDK7_CDK7_ST	Q01094	E2F1	P50613	CDK7	S364	V369M	369	Missense	distal	5	no	15.270	16.086	EPSD	ICGC	13.598	Up-regulation
CMGC_CDK_CDK7_CDK7_ST	Q01094	E2F1	P50613	CDK7	S364	R361Q	361	Missense	distal	-3	no	15.270	10.975	EPSD	ICGC	13.598	Loss
CMGC_CDK_CDK7_CDK7_ST	Q01094	E2F1	P50613	CDK7	S364	S360F	360	Missense	distal	-4	no	15.270	16.042	EPSD	ICGC	13.598	Up-regulation
CMGC_CDK_CDK7_CDK7_ST	Q01094	E2F1	P50613	CDK7	S403	A408V	408	Missense	distal	5	no	24.807	22.765	EPSD;PhosphoSitePlus	ICGC;COSMIC	13.598	Down-regulation
CMGC_CDK_CDK7_CDK7_ST	Q01094	E2F1	P50613	CDK7	S403	E397K	397	Missense	distal	-6	no	24.807	24.513	EPSD;PhosphoSitePlus	ICGC;COSMIC	13.598	Down-regulation
CMGC_CDK_CDK7_CDK7_ST	Q15797	SMAD1	P50613	CDK7	S195	T202A	202	Missense	distal	7	no	25.333	27.439	EPSD	ICGC;COSMIC	13.598	Up-regulation
CMGC_CDK_CDK7_CDK7_ST	Q15797	SMAD1	P50613	CDK7	S195	G197W	197	Missense	proximal	2	no	25.333	28.147	EPSD	ICGC;COSMIC	13.598	Up-regulation
CMGC_CDK_CDK7_CDK7_ST	Q15797	SMAD1	P50613	CDK7	S195	P188T	188	Missense	distal	-7	no	25.333	24.736	EPSD	ICGC;COSMIC	13.598	Down-regulation
CMGC_CDK_CDK7_CDK7_ST	Q15797	SMAD1	P50613	CDK7	S206	T202A	202	Missense	distal	-4	no	24.195	24.203	PhosphoSitePlus	ICGC;COSMIC	13.598	Up-regulation
CMGC_CDK_CDK7_CDK7_ST	Q15797	SMAD1	P50613	CDK7	S456	P457L	457	Missense	proximal	1	no	15.128	7.657	EPSD	ICGC;COSMIC	13.598	Loss
CMGC_CDK_CDK7_CDK7_ST	P06493	CDK1	P50613	CDK7	S46	R50L	50	Missense	distal	4	no	14.793	12.768	EPSD	ICGC;COSMIC	13.598	Loss
CMGC_CDK_CDK7_CDK7_ST	P06493	CDK1	P50613	CDK7	S46	P45S	45	Missense	proximal	-1	no	14.793	15.047	EPSD	ICGC	13.598	Up-regulation
CMGC_CDK_CDK7_CDK7_ST	P06493	CDK1	P50613	CDK7	S53	R59H	59	Missense	distal	6	no	21.987	21.314	EPSD	ICGC;COSMIC	13.598	Down-regulation
CMGC_CDK_CDK7_CDK7_ST	P06493	CDK1	P50613	CDK7	S53	R50L	50	Missense	distal	-3	no	21.987	19.040	EPSD	ICGC;COSMIC	13.598	Down-regulation
CMGC_CDK_CDK7_CDK7_ST	P06493	CDK1	P50613	CDK7	S208	G206R	206	Missense	proximal	-2	no	19.691	19.560	EPSD	ICGC	13.598	Down-regulation
CMGC_CDK_CDK7_CDK7_ST	P06493	CDK1	P50613	CDK7	S208	P202Q	202	Missense	distal	-6	no	19.691	19.387	EPSD	ICGC;COSMIC	13.598	Down-regulation
CMGC_CDK_CDK7_CDK7_ST	Q9BYE7	PCGF6	P50613	CDK7	S115	G110E	110	Missense	distal	-5	no	14.289	17.214	EPSD	ICGC	13.598	Up-regulation
CMGC_CDK_CDK7_CDK7_ST	P13631	RARG	P50613	CDK7	S43	S43R	43	Missense	central	0	yes	21.011	0.000	EPSD	ICGC	13.598	Loss
CMGC_CDK_CDK7_CDK7_ST	P13631	RARG	P50613	CDK7	S43	P44T	44	Missense	proximal	1	no	21.011	13.850	EPSD	ICGC	13.598	Down-regulation
CMGC_CDK_CDK7_CDK7_ST	P13631	RARG	P50613	CDK7	S43	L42P	42	Missense	proximal	-1	no	21.011	21.039	EPSD	ICGC;COSMIC	13.598	Up-regulation
CMGC_CDK_CDK7_CDK7_ST	P13631	RARG	P50613	CDK7	S426	P431H	431	Missense	distal	5	no	14.472	12.291	EPSD	ICGC	13.598	Loss
CMGC_CDK_CDK7_CDK7_ST	P13631	RARG	P50613	CDK7	S426	P431S	431	Missense	distal	5	no	14.472	15.857	EPSD	ICGC;COSMIC	13.598	Up-regulation
CMGC_CDK_CDK7_CDK7_ST	Q9NYV4	CDK12	P50613	CDK7	T57	G54V	54	Missense	distal	-3	no	17.245	17.865	EPSD	ICGC	13.598	Up-regulation
CMGC_CDK_CDK7_CDK7_ST	Q9NYV4	CDK12	P50613	CDK7	T57	L63M	63	Missense	distal	6	no	17.245	17.582	EPSD	ICGC;COSMIC	13.598	Up-regulation
CMGC_CDK_CDK7_CDK7_ST	Q9NYV4	CDK12	P50613	CDK7	S62	L63M	63	Missense	proximal	1	no	16.417	11.571	EPSD	ICGC;COSMIC	13.598	Loss
CMGC_CDK_CDK7_CDK7_ST	Q9NYV4	CDK12	P50613	CDK7	T82	M87I	87	Missense	distal	5	no	13.919	14.099	EPSD	ICGC	13.598	Up-regulation
CMGC_CDK_CDK7_CDK7_ST	Q9NYV4	CDK12	P50613	CDK7	T206	K199T	199	Missense	distal	-7	no	19.298	17.044	EPSD	ICGC	13.598	Down-regulation
CMGC_CDK_CDK7_CDK7_ST	Q9NYV4	CDK12	P50613	CDK7	T206	T212I	212	Missense	distal	6	no	19.298	19.250	EPSD	ICGC;COSMIC	13.598	Down-regulation
CMGC_CDK_CDK7_CDK7_ST	Q9NYV4	CDK12	P50613	CDK7	T206	K208T	208	Missense	proximal	2	no	19.298	17.936	EPSD	ICGC;COSMIC	13.598	Down-regulation
CMGC_CDK_CDK7_CDK7_ST	Q9NYV4	CDK12	P50613	CDK7	S215	D214Y	214	Missense	proximal	-1	no	24.898	25.216	EPSD	ICGC;COSMIC;GDSC;CCLE	13.598	Up-regulation
CMGC_CDK_CDK7_CDK7_ST	Q9NYV4	CDK12	P50613	CDK7	S215	T212I	212	Missense	distal	-3	no	24.898	23.818	EPSD	ICGC;COSMIC	13.598	Down-regulation
CMGC_CDK_CDK7_CDK7_ST	Q9NYV4	CDK12	P50613	CDK7	S215	R219T	219	Missense	distal	4	no	24.898	22.682	EPSD	ICGC;COSMIC	13.598	Down-regulation
CMGC_CDK_CDK7_CDK7_ST	Q9NYV4	CDK12	P50613	CDK7	S215	K208T	208	Missense	distal	-7	no	24.898	22.644	EPSD	ICGC;COSMIC	13.598	Down-regulation
CMGC_CDK_CDK7_CDK7_ST	Q9NYV4	CDK12	P50613	CDK7	S222	R219T	219	Missense	distal	-3	no	15.259	12.047	EPSD	ICGC;COSMIC	13.598	Loss
CMGC_CDK_CDK7_CDK7_ST	Q9NYV4	CDK12	P50613	CDK7	S228	S231Y	231	Missense	distal	3	no	13.383	14.054	EPSD	ICGC;COSMIC	13.598	Gain
CMGC_CDK_CDK7_CDK7_ST	Q9NYV4	CDK12	P50613	CDK7	S287	Y285C	285	Missense	proximal	-2	no	23.902	23.611	EPSD	ICGC;COSMIC	13.598	Down-regulation
CMGC_CDK_CDK7_CDK7_ST	Q9NYV4	CDK12	P50613	CDK7	S287	P282L	282	Missense	distal	-5	no	23.902	22.459	EPSD	ICGC	13.598	Down-regulation
CMGC_CDK_CDK7_CDK7_ST	Q9NYV4	CDK12	P50613	CDK7	S291	Y285C	285	Missense	distal	-6	no	16.900	16.592	EPSD	ICGC;COSMIC	13.598	Down-regulation
CMGC_CDK_CDK7_CDK7_ST	Q9NYV4	CDK12	P50613	CDK7	S311	P304T	304	Missense	distal	-7	no	24.606	24.010	EPSD	ICGC;COSMIC	13.598	Down-regulation
CMGC_CDK_CDK7_CDK7_ST	Q9NYV4	CDK12	P50613	CDK7	S311	G317C	317	Missense	distal	6	no	24.606	25.608	EPSD	ICGC	13.598	Up-regulation
CMGC_CDK_CDK7_CDK7_ST	Q9NYV4	CDK12	P50613	CDK7	S318	G317C	317	Missense	proximal	-1	no	13.695	13.933	EPSD	ICGC	13.598	Up-regulation
CMGC_CDK_CDK7_CDK7_ST	Q9NYV4	CDK12	P50613	CDK7	S325	G328C	328	Missense	distal	3	no	15.666	16.211	EPSD	ICGC	13.598	Up-regulation
CMGC_CDK_CDK7_CDK7_ST	Q9NYV4	CDK12	P50613	CDK7	S333	S334C	334	Missense	proximal	1	no	13.774	12.585	EPSD	ICGC;COSMIC	13.598	Loss
CMGC_CDK_CDK7_CDK7_ST	Q9NYV4	CDK12	P50613	CDK7	S333	G328C	328	Missense	distal	-5	no	13.774	14.798	EPSD	ICGC	13.598	Up-regulation
CMGC_CDK_CDK7_CDK7_ST	Q9NYV4	CDK12	P50613	CDK7	S334	S334C	334	Missense	central	0	yes	15.999	0.000	EPSD	ICGC;COSMIC	13.598	Loss
CMGC_CDK_CDK7_CDK7_ST	Q9NYV4	CDK12	P50613	CDK7	S334	G328C	328	Missense	distal	-6	no	15.999	15.964	EPSD	ICGC	13.598	Down-regulation
CMGC_CDK_CDK7_CDK7_ST	Q9NYV4	CDK12	P50613	CDK7	S334	S341Y	341	Missense	distal	7	no	15.999	17.248	EPSD	ICGC;COSMIC	13.598	Up-regulation
CMGC_CDK_CDK7_CDK7_ST	Q9NYV4	CDK12	P50613	CDK7	S343	S341Y	341	Missense	proximal	-2	no	13.822	13.493	EPSD	ICGC;COSMIC	13.598	Loss
CMGC_CDK_CDK7_CDK7_ST	Q9NYV4	CDK12	P50613	CDK7	S343	P348T	348	Missense	distal	5	no	13.822	12.986	EPSD	ICGC;COSMIC	13.598	Loss
CMGC_CDK_CDK7_CDK7_ST	Q9NYV4	CDK12	P50613	CDK7	S345	S341Y	341	Missense	distal	-4	no	15.512	15.942	EPSD	ICGC;COSMIC	13.598	Up-regulation
CMGC_CDK_CDK7_CDK7_ST	Q9NYV4	CDK12	P50613	CDK7	S345	P348T	348	Missense	distal	3	no	15.512	15.294	EPSD	ICGC;COSMIC	13.598	Down-regulation
CMGC_CDK_CDK7_CDK7_ST	Q9NYV4	CDK12	P50613	CDK7	S349	R356I	356	Missense	distal	7	no	15.490	15.965	EPSD	ICGC;COSMIC	13.598	Up-regulation
CMGC_CDK_CDK7_CDK7_ST	Q9NYV4	CDK12	P50613	CDK7	S349	P348T	348	Missense	proximal	-1	no	15.490	15.497	EPSD	ICGC;COSMIC	13.598	Up-regulation
CMGC_CDK_CDK7_CDK7_ST	Q9NYV4	CDK12	P50613	CDK7	S681	P683T	683	Missense	proximal	2	no	13.627	13.494	EPSD	ICGC;COSMIC	13.598	Loss
CMGC_CDK_CDK7_CDK7_ST	Q9NYV4	CDK12	P50613	CDK7	S685	P683T	683	Missense	proximal	-2	no	15.799	15.629	EPSD	ICGC;COSMIC	13.598	Down-regulation
CMGC_CDK_CDK7_CDK7_ST	Q9NYV4	CDK12	P50613	CDK7	S838	H835N	835	Missense	distal	-3	no	16.125	15.198	EPSD	ICGC;COSMIC	13.598	Down-regulation
CMGC_CDK_CDK7_CDK7_ST	Q9NYV4	CDK12	P50613	CDK7	S886	R890L	890	Missense	distal	4	no	14.165	12.140	EPSD	ICGC	13.598	Loss
CMGC_CDK_CDK7_CDK7_ST	Q9NYV4	CDK12	P50613	CDK7	S886	R882L	882	Missense	distal	-4	no	14.165	14.245	EPSD	ICGC;COSMIC	13.598	Up-regulation
CMGC_CDK_CDK7_CDK7_ST	Q9NYV4	CDK12	P50613	CDK7	T893	V896A	896	Missense	distal	3	no	23.282	23.147	PhosphoSitePlus	ICGC;COSMIC	13.598	Down-regulation
CMGC_CDK_CDK7_CDK7_ST	Q9NYV4	CDK12	P50613	CDK7	T893	R890L	890	Missense	distal	-3	no	23.282	20.334	PhosphoSitePlus	ICGC	13.598	Down-regulation
CMGC_CDK_CDK7_CDK7_ST	Q9NYV4	CDK12	P50613	CDK7	S949	C952Y	952	Missense	distal	3	no	14.633	14.809	EPSD	ICGC;COSMIC	13.598	Up-regulation
CMGC_CDK_CDK7_CDK7_ST	Q9NYV4	CDK12	P50613	CDK7	S954	C952Y	952	Missense	proximal	-2	no	18.266	18.558	EPSD	ICGC;COSMIC	13.598	Up-regulation
CMGC_CDK_CDK7_CDK7_ST	Q9NYV4	CDK12	P50613	CDK7	S954	A958V	958	Missense	distal	4	no	18.266	17.828	EPSD	ICGC;COSMIC	13.598	Down-regulation
CMGC_CDK_CDK7_CDK7_ST	Q9NYV4	CDK12	P50613	CDK7	S954	V959G	959	Missense	distal	5	no	18.266	19.491	EPSD	ICGC;COSMIC	13.598	Up-regulation
CMGC_CDK_CDK7_CDK7_ST	Q9NYV4	CDK12	P50613	CDK7	S1063	S1063P	1063	Missense	central	0	yes	14.709	0.000	EPSD	ICGC;COSMIC	13.598	Loss
CMGC_CDK_CDK7_CDK7_ST	Q9NYV4	CDK12	P50613	CDK7	S1083	E1077Q	1077	Missense	distal	-6	no	16.701	16.308	EPSD	ICGC;COSMIC	13.598	Down-regulation
CMGC_CDK_CDK7_CDK7_ST	Q9NYV4	CDK12	P50613	CDK7	S1083	S1082N	1082	Missense	proximal	-1	no	16.701	16.699	EPSD	ICGC;COSMIC	13.598	Down-regulation
CMGC_CDK_CDK7_CDK7_ST	Q9NYV4	CDK12	P50613	CDK7	T1195	L1197I	1197	Missense	proximal	2	no	13.445	14.545	EPSD	ICGC;COSMIC	13.598	Gain
CMGC_CDK_CDK7_CDK7_ST	Q9NYV4	CDK12	P50613	CDK7	T1244	R1242Q	1242	Missense	proximal	-2	no	18.395	18.468	EPSD	ICGC;COSMIC	13.598	Up-regulation
CMGC_CDK_CDK7_CDK7_ST	Q9NYV4	CDK12	P50613	CDK7	T1244	G1237W	1237	Missense	distal	-7	no	18.395	19.250	EPSD	ICGC	13.598	Up-regulation
CMGC_CDK_CDK7_CDK7_ST	Q9NYV4	CDK12	P50613	CDK7	T1244	E1250D	1250	Missense	distal	6	no	18.395	16.549	EPSD	ICGC	13.598	Down-regulation
CMGC_CDK_CDK7_CDK7_ST	P10275	AR	P50613	CDK7	S258	G260V	260	Missense	proximal	2	no	23.761	23.954	EPSD	ICGC;COSMIC	13.598	Up-regulation
CMGC_CDK_CDK7_CDK7_ST	P10275	AR	P50613	CDK7	S310	T317A	317	Missense	distal	7	no	14.097	16.204	EPSD	ICGC;COSMIC	13.598	Up-regulation
CMGC_CDK_CDK7_CDK7_ST	P10275	AR	P50613	CDK7	S310	T303S	303	Missense	distal	-7	no	14.097	12.616	EPSD	ICGC;COSMIC	13.598	Loss
CMGC_CDK_CDK7_CDK7_ST	P10275	AR	P50613	CDK7	S310	G314R	314	Missense	distal	4	no	14.097	16.495	EPSD	ICGC	13.598	Up-regulation
CMGC_CDK_CDK7_CDK7_ST	P10275	AR	P50613	CDK7	S516	Y514H	514	Missense	proximal	-2	no	26.004	25.557	PhosphoSitePlus	ICGC;GDSC;CCLE	13.598	Down-regulation
CMGC_CDK_CDK7_CDK7_ST	P10275	AR	P50613	CDK7	S516	S516I	516	Missense	central	0	yes	26.004	0.000	PhosphoSitePlus	ICGC	13.598	Loss
CMGC_CDK_CDK7_CDK7_ST	P10275	AR	P50613	CDK7	S516	V509L	509	Missense	distal	-7	no	26.004	27.976	PhosphoSitePlus	ICGC;COSMIC	13.598	Up-regulation
CMGC_CDK_CDK7_CDK7_ST	Q13285	NR5A1	P50613	CDK7	S203	A202V	202	Missense	proximal	-1	no	44.824	44.564	PhosphoSitePlus	ICGC;COSMIC	13.598	Down-regulation
CMGC_CDK_CDK7_CDK7_ST	Q13285	NR5A1	P50613	CDK7	S203	P207H	207	Missense	distal	4	no	44.824	43.231	PhosphoSitePlus	ICGC	13.598	Down-regulation
AGC_NDR_NDR_STK38_ST	P46937	YAP1	Q15208	STK38	S109	T110S	110	Missense	proximal	1	no	2.160	2.158	EPSD;PhosphoSitePlus	ICGC;COSMIC	0.133	Down-regulation
AGC_NDR_NDR_STK38_ST	P46937	YAP1	Q15208	STK38	S127	Q133L	133	Missense	distal	6	no	2.198	2.199	EPSD;PhosphoSitePlus	ICGC;COSMIC	0.133	Up-regulation
AGC_NDR_NDR_STK38_ST	P46937	YAP1	Q15208	STK38	S127	L134F	134	Missense	distal	7	no	2.198	2.199	EPSD;PhosphoSitePlus	ICGC;COSMIC	0.133	Up-regulation
AGC_NDR_NDR_STK38_ST	P46937	YAP1	Q15208	STK38	S127	H126R	126	Missense	proximal	-1	no	2.198	2.186	EPSD;PhosphoSitePlus	ICGC;COSMIC	0.133	Down-regulation
AGC_NDR_NDR_STK38_ST	P46937	YAP1	Q15208	STK38	S131	Q133L	133	Missense	proximal	2	no	1.533	1.532	EPSD	ICGC;COSMIC	0.133	Down-regulation
AGC_NDR_NDR_STK38_ST	P46937	YAP1	Q15208	STK38	S131	L134F	134	Missense	distal	3	no	1.533	1.534	EPSD	ICGC;COSMIC	0.133	Up-regulation
AGC_NDR_NDR_STK38_ST	P46937	YAP1	Q15208	STK38	S131	H126R	126	Missense	distal	-5	no	1.533	0.063	EPSD	ICGC;COSMIC	0.133	Loss
AGC_NDR_NDR_STK38_ST	P46937	YAP1	Q15208	STK38	S164	S163F	163	Missense	proximal	-1	no	2.147	2.150	EPSD;PhosphoSitePlus	ICGC;COSMIC	0.133	Up-regulation
AGC_NDR_NDR_STK38_ST	P46937	YAP1	Q15208	STK38	S164	R161L	161	Missense	distal	-3	no	2.147	1.693	EPSD;PhosphoSitePlus	ICGC	0.133	Down-regulation
AGC_NDR_NDR_STK38_ST	P46937	YAP1	Q15208	STK38	S164	S164F	164	Missense	central	0	yes	2.147	0.000	EPSD;PhosphoSitePlus	ICGC	0.133	Loss
AGC_NDR_NDR_STK38_ST	P46937	YAP1	Q15208	STK38	S336	R331W	331	Missense	distal	-5	no	0.177	-0.008	EPSD	ICGC;COSMIC	0.133	Loss
AGC_NDR_NDR_STK38_ST	P46937	YAP1	Q15208	STK38	T378	Q372R	372	Missense	distal	-6	no	0.315	0.312	EPSD	ICGC;COSMIC	0.133	Down-regulation
AGC_NDR_NDR_STK38_ST	P46937	YAP1	Q15208	STK38	S397	R394Q	394	Missense	distal	-3	no	2.158	1.640	EPSD	ICGC;COSMIC	0.133	Down-regulation
AGC_NDR_NDR_STK38_ST	P46937	YAP1	Q15208	STK38	S397	S397I	397	Missense	central	0	yes	2.158	0.000	EPSD	ICGC	0.133	Loss
AGC_NDR_NDR_STK38_ST	P46937	YAP1	Q15208	STK38	S397	H392N	392	Missense	distal	-5	no	2.158	0.441	EPSD	ICGC;COSMIC	0.133	Down-regulation
AGC_NDR_NDR_STK38_ST	Q15208	STK38	Q15208	STK38	S252	Y246H	246	Missense	distal	-6	no	0.229	0.233	EPSD	ICGC	0.133	Up-regulation
AGC_NDR_NDR_STK38_ST	Q15208	STK38	Q15208	STK38	S281	R276C	276	Missense	distal	-5	no	0.268	0.090	EPSD;PhosphoSitePlus	ICGC;COSMIC	0.133	Loss
AGC_NDR_NDR_STK38_ST	Q15208	STK38	Q15208	STK38	S281	A279D	279	Missense	proximal	-2	no	0.268	0.263	EPSD;PhosphoSitePlus	ICGC	0.133	Down-regulation
AGC_NDR_NDR_STK38_ST	Q15208	STK38	Q15208	STK38	T444	T444M	444	Missense	central	0	yes	0.239	0.000	PhosphoSitePlus;EPSD	ICGC;COSMIC	0.133	Loss
AGC_NDR_NDR_STK38_ST	Q96QF0	RAB3IP	Q15208	STK38	T46	T46M	46	Missense	central	0	yes	0.134	0.000	EPSD	ICGC;COSMIC	0.133	Loss
AGC_NDR_NDR_STK38_ST	Q96QF0	RAB3IP	Q15208	STK38	S163	R160L	160	Missense	distal	-3	no	0.358	-0.096	EPSD	ICGC;COSMIC	0.133	Loss
AGC_NDR_NDR_STK38_ST	Q96QF0	RAB3IP	Q15208	STK38	S163	R160Q	160	Missense	distal	-3	no	0.358	-0.159	EPSD	ICGC;COSMIC	0.133	Loss
AGC_NDR_NDR_STK38_ST	Q96QF0	RAB3IP	Q15208	STK38	S165	R160L	160	Missense	distal	-5	no	0.642	0.324	EPSD	ICGC;COSMIC	0.133	Down-regulation
AGC_NDR_NDR_STK38_ST	Q96QF0	RAB3IP	Q15208	STK38	S165	R160Q	160	Missense	distal	-5	no	0.642	0.371	EPSD	ICGC;COSMIC	0.133	Down-regulation
AGC_NDR_NDR_STK38_ST	Q02241	KIF23	Q15208	STK38	T8	A6S	6	Missense	proximal	-2	no	0.263	0.262	EPSD	ICGC	0.133	Down-regulation
AGC_NDR_NDR_STK38_ST	Q02241	KIF23	Q15208	STK38	T83	G80V	80	Missense	distal	-3	no	0.126	0.142	EPSD	ICGC;COSMIC	0.133	Gain
AGC_NDR_NDR_STK38_ST	Q02241	KIF23	Q15208	STK38	S718	S721Y	721	Missense	distal	3	no	0.148	0.147	EPSD	ICGC;COSMIC	0.133	Down-regulation
CAMK_CAMKL_AMPK_PRKAA1_ST	Q9Y478	PRKAB1	Q13131	PRKAA1	S24	P20H	20	Missense	distal	-4	no	60.885	59.806	EPSD;PhosphoSitePlus	ICGC	56.683	Down-regulation
CAMK_CAMKL_AMPK_PRKAA1_ST	Q9Y478	PRKAB1	Q13131	PRKAA1	S24	G31W	31	Missense	distal	7	no	60.885	60.575	EPSD;PhosphoSitePlus	ICGC;COSMIC	56.683	Down-regulation
CAMK_CAMKL_AMPK_PRKAA1_ST	Q9Y478	PRKAB1	Q13131	PRKAA1	S25	P20H	20	Missense	distal	-5	no	60.119	58.302	EPSD	ICGC	56.683	Down-regulation
CAMK_CAMKL_AMPK_PRKAA1_ST	Q9Y478	PRKAB1	Q13131	PRKAA1	S25	G31W	31	Missense	distal	6	no	60.119	59.750	EPSD	ICGC;COSMIC	56.683	Down-regulation
CAMK_CAMKL_AMPK_PRKAA1_ST	Q9Y478	PRKAB1	Q13131	PRKAA1	T80	R83Q	83	Missense	distal	3	no	58.942	60.336	EPSD;PhosphoSitePlus	ICGC;COSMIC	56.683	Up-regulation
CAMK_CAMKL_AMPK_PRKAA1_ST	Q9Y478	PRKAB1	Q13131	PRKAA1	T80	R78P	78	Missense	proximal	-2	no	58.942	60.731	EPSD;PhosphoSitePlus	ICGC;COSMIC	56.683	Up-regulation
CAMK_CAMKL_AMPK_PRKAA1_ST	Q9Y478	PRKAB1	Q13131	PRKAA1	S96	K89N	89	Missense	distal	-7	no	58.453	56.755	EPSD	ICGC	56.683	Down-regulation
CAMK_CAMKL_AMPK_PRKAA1_ST	Q9Y478	PRKAB1	Q13131	PRKAA1	S101	P104S	104	Missense	distal	3	no	56.896	59.134	EPSD	ICGC	56.683	Up-regulation
CAMK_CAMKL_AMPK_PRKAA1_ST	Q9Y478	PRKAB1	Q13131	PRKAA1	S108	P104S	104	Missense	distal	-4	no	64.453	65.696	PhosphoSitePlus;EPSD	ICGC	56.683	Up-regulation
CAMK_CAMKL_AMPK_PRKAA1_ST	Q9Y478	PRKAB1	Q13131	PRKAA1	T158	K156N	156	Missense	proximal	-2	no	62.227	61.428	EPSD;PhosphoSitePlus	ICGC	56.683	Down-regulation
CAMK_CAMKL_AMPK_PRKAA1_ST	Q9Y478	PRKAB1	Q13131	PRKAA1	S177	S170F	170	Missense	distal	-7	no	61.246	58.653	EPSD;PhosphoSitePlus	ICGC	56.683	Down-regulation
CAMK_CAMKL_AMPK_PRKAA1_ST	P10636	MAPT	Q13131	PRKAA1	S171	R164T	164	Missense	distal	-7	no	59.279	58.422	EPSD	ICGC;COSMIC	56.683	Down-regulation
CAMK_CAMKL_AMPK_PRKAA1_ST	P10636	MAPT	Q13131	PRKAA1	S171	A166T	166	Missense	distal	-5	no	59.279	57.287	EPSD	ICGC	56.683	Down-regulation
CAMK_CAMKL_AMPK_PRKAA1_ST	P10636	MAPT	Q13131	PRKAA1	S214	G208C	208	Missense	distal	-6	no	71.752	68.640	EPSD;PhosphoSitePlus	ICGC;COSMIC	56.683	Down-regulation
CAMK_CAMKL_AMPK_PRKAA1_ST	P10636	MAPT	Q13131	PRKAA1	S214	R211S	211	Missense	distal	-3	no	71.752	62.357	EPSD;PhosphoSitePlus	ICGC;COSMIC	56.683	Down-regulation
CAMK_CAMKL_AMPK_PRKAA1_ST	P10636	MAPT	Q13131	PRKAA1	S214	G213E	213	Missense	proximal	-1	no	71.752	71.665	EPSD;PhosphoSitePlus	ICGC;COSMIC	56.683	Down-regulation
CAMK_CAMKL_AMPK_PRKAA1_ST	P10636	MAPT	Q13131	PRKAA1	S516	G521R	521	Missense	distal	5	no	62.451	62.530	EPSD	ICGC;COSMIC	56.683	Up-regulation
CAMK_CAMKL_AMPK_PRKAA1_ST	Q7Z3C6	ATG9A	Q13131	PRKAA1	S738	S738C	738	Missense	central	0	yes	63.700	0.000	EPSD	ICGC;COSMIC	56.683	Loss
CAMK_CAMKL_AMPK_PRKAA1_ST	Q7Z628	NET1	Q13131	PRKAA1	S24	R18L	18	Missense	distal	-6	no	58.467	58.307	EPSD	ICGC	56.683	Down-regulation
CAMK_CAMKL_AMPK_PRKAA1_ST	Q7Z628	NET1	Q13131	PRKAA1	S51	P57T	57	Missense	distal	6	no	67.889	67.838	EPSD	ICGC;COSMIC;CCLE	56.683	Down-regulation
CAMK_CAMKL_AMPK_PRKAA1_ST	Q7Z628	NET1	Q13131	PRKAA1	S51	R47Q	47	Missense	distal	-4	no	67.889	66.420	EPSD	ICGC;CCLE	56.683	Down-regulation
CAMK_CAMKL_AMPK_PRKAA1_ST	Q7Z628	NET1	Q13131	PRKAA1	S78	S81I	81	Missense	distal	3	no	59.453	57.075	EPSD	ICGC	56.683	Down-regulation
CAMK_CAMKL_AMPK_PRKAA1_ST	Q7Z628	NET1	Q13131	PRKAA1	S78	K85R	85	Missense	distal	7	no	59.453	60.339	EPSD	ICGC;COSMIC	56.683	Up-regulation
CAMK_CAMKL_AMPK_PRKAA1_ST	Q7Z628	NET1	Q13131	PRKAA1	S80	S81I	81	Missense	proximal	1	no	62.041	60.462	EPSD	ICGC	56.683	Down-regulation
CAMK_CAMKL_AMPK_PRKAA1_ST	Q7Z628	NET1	Q13131	PRKAA1	S80	K85R	85	Missense	distal	5	no	62.041	62.100	EPSD	ICGC;COSMIC	56.683	Up-regulation
CAMK_CAMKL_AMPK_PRKAA1_ST	Q7Z628	NET1	Q13131	PRKAA1	S100	L104V	104	Missense	distal	4	no	72.161	67.664	PhosphoSitePlus	ICGC;COSMIC	56.683	Down-regulation
CAMK_CAMKL_AMPK_PRKAA1_ST	Q7Z628	NET1	Q13131	PRKAA1	S100	R97P	97	Missense	distal	-3	no	72.161	63.301	PhosphoSitePlus	ICGC;COSMIC	56.683	Down-regulation
CAMK_CAMKL_AMPK_PRKAA1_ST	Q7Z628	NET1	Q13131	PRKAA1	S539	Q535K	535	Missense	distal	-4	no	63.855	62.143	EPSD	ICGC;COSMIC	56.683	Down-regulation
CAMK_CAMKL_AMPK_PRKAA1_ST	Q7Z628	NET1	Q13131	PRKAA1	T540	Q535K	535	Missense	distal	-5	no	54.232	56.824	EPSD	ICGC;COSMIC	56.683	Gain
CAMK_CAMKL_AMPK_PRKAA1_ST	P07954	FH	Q13131	PRKAA1	T56	F50I	50	Missense	distal	-6	no	64.956	62.180	EPSD	ICGC	56.683	Down-regulation
CAMK_CAMKL_AMPK_PRKAA1_ST	P07954	FH	Q13131	PRKAA1	T56	F50L	50	Missense	distal	-6	no	64.956	65.164	EPSD	ICGC	56.683	Up-regulation
CAMK_CAMKL_AMPK_PRKAA1_ST	Q8IY63	AMOTL1	Q13131	PRKAA1	S76	N73D	73	Missense	distal	-3	no	62.687	58.770	EPSD	ICGC;COSMIC	56.683	Down-regulation
CAMK_CAMKL_AMPK_PRKAA1_ST	Q8IY63	AMOTL1	Q13131	PRKAA1	S76	R81S	81	Missense	distal	5	no	62.687	62.652	EPSD	ICGC;COSMIC	56.683	Down-regulation
CAMK_CAMKL_AMPK_PRKAA1_ST	Q8IY63	AMOTL1	Q13131	PRKAA1	S262	V258I	258	Missense	distal	-4	no	64.416	63.010	EPSD	ICGC;COSMIC	56.683	Down-regulation
CAMK_CAMKL_AMPK_PRKAA1_ST	Q8IY63	AMOTL1	Q13131	PRKAA1	S724	R721Q	721	Missense	distal	-3	no	58.458	50.513	EPSD	ICGC;COSMIC	56.683	Loss
CAMK_CAMKL_AMPK_PRKAA1_ST	Q8IY63	AMOTL1	Q13131	PRKAA1	S724	R721L	721	Missense	distal	-3	no	58.458	48.491	EPSD	ICGC;COSMIC	56.683	Loss
CAMK_CAMKL_AMPK_PRKAA1_ST	Q8IY63	AMOTL1	Q13131	PRKAA1	S793	R792H	792	Missense	proximal	-1	no	58.596	58.615	PhosphoSitePlus	ICGC;COSMIC	56.683	Up-regulation
CAMK_CAMKL_AMPK_PRKAA1_ST	Q8IY63	AMOTL1	Q13131	PRKAA1	S793	V794I	794	Missense	proximal	1	no	58.596	57.153	PhosphoSitePlus	ICGC;COSMIC	56.683	Down-regulation
CAMK_CAMKL_AMPK_PRKAA1_ST	Q8IY63	AMOTL1	Q13131	PRKAA1	S793	S793Y	793	Missense	central	0	yes	58.596	0.000	PhosphoSitePlus	ICGC;COSMIC	56.683	Loss
CAMK_CAMKL_AMPK_PRKAA1_ST	Q13131	PRKAA1	Q13131	PRKAA1	T37	G36D	36	Missense	proximal	-1	no	56.820	56.814	EPSD	ICGC	56.683	Down-regulation
CAMK_CAMKL_AMPK_PRKAA1_ST	Q13131	PRKAA1	Q13131	PRKAA1	T37	K42N	42	Missense	distal	5	no	56.820	56.807	EPSD	ICGC;COSMIC	56.683	Down-regulation
CAMK_CAMKL_AMPK_PRKAA1_ST	Q13131	PRKAA1	Q13131	PRKAA1	S65	R64Q	64	Missense	proximal	-1	no	59.336	59.364	EPSD	ICGC;COSMIC	56.683	Up-regulation
CAMK_CAMKL_AMPK_PRKAA1_ST	Q13131	PRKAA1	Q13131	PRKAA1	S65	V69A	69	Missense	distal	4	no	59.336	59.302	EPSD	ICGC	56.683	Down-regulation
CAMK_CAMKL_AMPK_PRKAA1_ST	Q13131	PRKAA1	Q13131	PRKAA1	S176	L171V	171	Missense	distal	-5	no	63.123	58.259	EPSD	ICGC;COSMIC	56.683	Down-regulation
CAMK_CAMKL_AMPK_PRKAA1_ST	Q13131	PRKAA1	Q13131	PRKAA1	S176	T183K	183	Missense	distal	7	no	63.123	61.896	EPSD	ICGC	56.683	Down-regulation
CAMK_CAMKL_AMPK_PRKAA1_ST	Q13131	PRKAA1	Q13131	PRKAA1	S176	N173H	173	Missense	distal	-3	no	63.123	61.202	EPSD	ICGC;COSMIC	56.683	Down-regulation
CAMK_CAMKL_AMPK_PRKAA1_ST	Q13131	PRKAA1	Q13131	PRKAA1	T183	N189S	189	Missense	distal	6	no	57.608	57.725	EPSD;PhosphoSitePlus	ICGC;COSMIC;CCLE	56.683	Up-regulation
CAMK_CAMKL_AMPK_PRKAA1_ST	Q13131	PRKAA1	Q13131	PRKAA1	T183	T183K	183	Missense	central	0	yes	57.608	0.000	EPSD;PhosphoSitePlus	ICGC	56.683	Loss
CAMK_CAMKL_AMPK_PRKAA1_ST	Q13131	PRKAA1	Q13131	PRKAA1	S293	E290D	290	Missense	distal	-3	no	57.093	55.722	EPSD	ICGC;COSMIC	56.683	Loss
CAMK_CAMKL_AMPK_PRKAA1_ST	Q13131	PRKAA1	Q13131	PRKAA1	S293	M298I	298	Missense	distal	5	no	57.093	57.201	EPSD	ICGC;COSMIC	56.683	Up-regulation
CAMK_CAMKL_AMPK_PRKAA1_ST	Q13131	PRKAA1	Q13131	PRKAA1	S360	H365Y	365	Missense	distal	5	no	57.590	57.835	EPSD;PhosphoSitePlus	ICGC;COSMIC	56.683	Up-regulation
CAMK_CAMKL_AMPK_PRKAA1_ST	Q13131	PRKAA1	Q13131	PRKAA1	S360	L362I	362	Missense	proximal	2	no	57.590	57.034	EPSD;PhosphoSitePlus	ICGC;COSMIC	56.683	Down-regulation
CAMK_CAMKL_AMPK_PRKAA1_ST	Q13131	PRKAA1	Q13131	PRKAA1	S360	A354V	354	Missense	distal	-6	no	57.590	55.738	EPSD;PhosphoSitePlus	ICGC;COSMIC	56.683	Loss
CAMK_CAMKL_AMPK_PRKAA1_ST	Q13131	PRKAA1	Q13131	PRKAA1	S360	S360F	360	Missense	central	0	yes	57.590	0.000	EPSD;PhosphoSitePlus	ICGC	56.683	Loss
CAMK_CAMKL_AMPK_PRKAA1_ST	Q13131	PRKAA1	Q13131	PRKAA1	T388	R386H	386	Missense	proximal	-2	no	61.746	59.025	EPSD;PhosphoSitePlus	ICGC;COSMIC	56.683	Down-regulation
CAMK_CAMKL_AMPK_PRKAA1_ST	Q13131	PRKAA1	Q13131	PRKAA1	T388	R386C	386	Missense	proximal	-2	no	61.746	54.635	EPSD;PhosphoSitePlus	ICGC;COSMIC	56.683	Loss
CAMK_CAMKL_AMPK_PRKAA1_ST	Q13131	PRKAA1	Q13131	PRKAA1	T388	P394A	394	Missense	distal	6	no	61.746	61.855	EPSD;PhosphoSitePlus	ICGC;COSMIC	56.683	Up-regulation
CAMK_CAMKL_AMPK_PRKAA1_ST	Q13131	PRKAA1	Q13131	PRKAA1	T388	L389I	389	Missense	proximal	1	no	61.746	61.093	EPSD;PhosphoSitePlus	ICGC;COSMIC	56.683	Down-regulation
CAMK_CAMKL_AMPK_PRKAA1_ST	Q13131	PRKAA1	Q13131	PRKAA1	T388	R384M	384	Missense	distal	-4	no	61.746	59.215	EPSD;PhosphoSitePlus	ICGC;COSMIC	56.683	Down-regulation
CAMK_CAMKL_AMPK_PRKAA1_ST	Q13131	PRKAA1	Q13131	PRKAA1	S397	S397Y	397	Missense	central	0	yes	61.571	0.000	EPSD	ICGC	56.683	Loss
CAMK_CAMKL_AMPK_PRKAA1_ST	Q13131	PRKAA1	Q13131	PRKAA1	S397	P394A	394	Missense	distal	-3	no	61.571	59.573	EPSD	ICGC;COSMIC	56.683	Down-regulation
CAMK_CAMKL_AMPK_PRKAA1_ST	Q13131	PRKAA1	Q13131	PRKAA1	S467	V465L	465	Missense	proximal	-2	no	60.859	58.425	EPSD	ICGC;COSMIC	56.683	Down-regulation
CAMK_CAMKL_AMPK_PRKAA1_ST	Q13131	PRKAA1	Q13131	PRKAA1	S467	Q464K	464	Missense	distal	-3	no	60.859	64.162	EPSD	ICGC;COSMIC	56.683	Up-regulation
CAMK_CAMKL_AMPK_PRKAA1_ST	Q13131	PRKAA1	Q13131	PRKAA1	S494	S498C	498	Missense	distal	4	no	60.164	40.416	PhosphoSitePlus;EPSD	ICGC;COSMIC	56.683	Loss
CAMK_CAMKL_AMPK_PRKAA1_ST	Q13131	PRKAA1	Q13131	PRKAA1	S494	R501P	501	Missense	distal	7	no	60.164	60.252	PhosphoSitePlus;EPSD	ICGC;COSMIC	56.683	Up-regulation
CAMK_CAMKL_AMPK_PRKAA1_ST	Q13131	PRKAA1	Q13131	PRKAA1	S494	Y500C	500	Missense	distal	6	no	60.164	60.301	PhosphoSitePlus;EPSD	ICGC;COSMIC	56.683	Up-regulation
CAMK_CAMKL_AMPK_PRKAA1_ST	Q13131	PRKAA1	Q13131	PRKAA1	S496	S498C	498	Missense	proximal	2	no	64.289	62.992	EPSD;PhosphoSitePlus	ICGC;COSMIC	56.683	Down-regulation
CAMK_CAMKL_AMPK_PRKAA1_ST	Q13131	PRKAA1	Q13131	PRKAA1	S496	R501P	501	Missense	distal	5	no	64.289	64.293	EPSD;PhosphoSitePlus	ICGC;COSMIC	56.683	Up-regulation
CAMK_CAMKL_AMPK_PRKAA1_ST	Q13131	PRKAA1	Q13131	PRKAA1	S496	C503Y	503	Missense	distal	7	no	64.289	65.090	EPSD;PhosphoSitePlus	ICGC	56.683	Up-regulation
CAMK_CAMKL_AMPK_PRKAA1_ST	Q13131	PRKAA1	Q13131	PRKAA1	S496	Y500C	500	Missense	distal	4	no	64.289	46.764	EPSD;PhosphoSitePlus	ICGC;COSMIC	56.683	Loss
CAMK_CAMKL_AMPK_PRKAA1_ST	Q13131	PRKAA1	Q13131	PRKAA1	S508	R501P	501	Missense	distal	-7	no	61.069	59.798	EPSD	ICGC;COSMIC	56.683	Down-regulation
CAMK_CAMKL_AMPK_PRKAA1_ST	Q13131	PRKAA1	Q13131	PRKAA1	S508	C503Y	503	Missense	distal	-5	no	61.069	58.562	EPSD	ICGC	56.683	Down-regulation
CAMK_CAMKL_AMPK_PRKAA1_ST	Q13131	PRKAA1	Q13131	PRKAA1	S508	R505M	505	Missense	distal	-3	no	61.069	48.186	EPSD	ICGC	56.683	Loss
CAMK_CAMKL_AMPK_PRKAA1_ST	Q13131	PRKAA1	Q13131	PRKAA1	S517	S524Y	524	Missense	distal	7	no	59.979	60.228	EPSD	ICGC;COSMIC	56.683	Up-regulation
CAMK_CAMKL_AMPK_PRKAA1_ST	Q13131	PRKAA1	Q13131	PRKAA1	S541	E545D	545	Missense	distal	4	no	53.506	57.422	EPSD	ICGC	56.683	Gain
CAMK_CAMKL_AMPK_PRKAA1_ST	Q13131	PRKAA1	Q13131	PRKAA1	S541	E545A	545	Missense	distal	4	no	53.506	60.216	EPSD	ICGC;COSMIC	56.683	Gain
CAMK_CAMKL_AMPK_PRKAA1_ST	Q15036	SNX17	Q13131	PRKAA1	S312	R314W	314	Missense	proximal	2	no	65.764	65.849	EPSD	ICGC;COSMIC	56.683	Up-regulation
CAMK_CAMKL_AMPK_PRKAA1_ST	Q15036	SNX17	Q13131	PRKAA1	S325	C320S	320	Missense	distal	-5	no	63.112	61.460	EPSD	ICGC;COSMIC	56.683	Down-regulation
CAMK_CAMKL_AMPK_PRKAA1_ST	Q9UQL6	HDAC5	Q13131	PRKAA1	S229	S225R	225	Missense	distal	-4	no	55.784	56.848	EPSD	ICGC;COSMIC	56.683	Gain
CAMK_CAMKL_AMPK_PRKAA1_ST	P04406	GAPDH	Q13131	PRKAA1	S122	G115S	115	Missense	distal	-7	no	57.178	56.759	PhosphoSitePlus	ICGC;COSMIC	56.683	Down-regulation
CAMK_CAMKL_AMPK_PRKAA1_ST	Q06210	GFPT1	Q13131	PRKAA1	S261	R258C	258	Missense	distal	-3	no	65.769	51.622	EPSD;PhosphoSitePlus	ICGC;COSMIC	56.683	Loss
CAMK_CAMKL_AMPK_PRKAA1_ST	Q06210	GFPT1	Q13131	PRKAA1	S261	T262K	262	Missense	proximal	1	no	65.769	66.690	EPSD;PhosphoSitePlus	ICGC;COSMIC	56.683	Up-regulation
CAMK_CAMKL_AMPK_PRKAA1_ST	Q06210	GFPT1	Q13131	PRKAA1	S261	L265I	265	Missense	distal	4	no	65.769	62.693	EPSD;PhosphoSitePlus	ICGC	56.683	Down-regulation
CAMK_CAMKL_AMPK_PRKAA1_ST	Q06210	GFPT1	Q13131	PRKAA1	S261	D260H	260	Missense	proximal	-1	no	65.769	65.755	EPSD;PhosphoSitePlus	ICGC;COSMIC	56.683	Down-regulation
CAMK_CAMKL_AMPK_PRKAA1_ST	P29474	NOS3	Q13131	PRKAA1	S260	G253V	253	Missense	distal	-7	no	57.537	55.739	EPSD	ICGC	56.683	Loss
CAMK_CAMKL_AMPK_PRKAA1_ST	P29474	NOS3	Q13131	PRKAA1	S260	G263R	263	Missense	distal	3	no	57.537	55.684	EPSD	ICGC	56.683	Loss
CAMK_CAMKL_AMPK_PRKAA1_ST	P29474	NOS3	Q13131	PRKAA1	S260	D264G	264	Missense	distal	4	no	57.537	57.179	EPSD	ICGC	56.683	Down-regulation
CAMK_CAMKL_AMPK_PRKAA1_ST	P29474	NOS3	Q13131	PRKAA1	T495	A500S	500	Missense	distal	5	no	60.541	60.495	EPSD	ICGC	56.683	Down-regulation
CAMK_CAMKL_AMPK_PRKAA1_ST	P29474	NOS3	Q13131	PRKAA1	T495	A502S	502	Missense	distal	7	no	60.541	60.413	EPSD	ICGC	56.683	Down-regulation
CAMK_CAMKL_AMPK_PRKAA1_ST	P29474	NOS3	Q13131	PRKAA1	T495	K493N	493	Missense	proximal	-2	no	60.541	59.743	EPSD	ICGC;COSMIC	56.683	Down-regulation
CAMK_CAMKL_AMPK_PRKAA1_ST	P29474	NOS3	Q13131	PRKAA1	S615	S617P	617	Missense	proximal	2	no	58.693	59.237	EPSD	ICGC;COSMIC	56.683	Up-regulation
CAMK_CAMKL_AMPK_PRKAA1_ST	P29474	NOS3	Q13131	PRKAA1	S615	S608I	608	Missense	distal	-7	no	58.693	56.342	EPSD	ICGC	56.683	Loss
CAMK_CAMKL_AMPK_PRKAA1_ST	P29474	NOS3	Q13131	PRKAA1	S615	P621T	621	Missense	distal	6	no	58.693	58.642	EPSD	ICGC;COSMIC	56.683	Down-regulation
CAMK_CAMKL_AMPK_PRKAA1_ST	P29474	NOS3	Q13131	PRKAA1	S633	R627W	627	Missense	distal	-6	no	77.542	72.730	EPSD;PhosphoSitePlus	ICGC;COSMIC	56.683	Down-regulation
CAMK_CAMKL_AMPK_PRKAA1_ST	P29474	NOS3	Q13131	PRKAA1	S633	R628W	628	Missense	distal	-5	no	77.542	72.349	EPSD;PhosphoSitePlus	ICGC;COSMIC	56.683	Down-regulation
CAMK_CAMKL_AMPK_PRKAA1_ST	P29474	NOS3	Q13131	PRKAA1	S634	R627W	627	Missense	distal	-7	no	61.470	63.269	EPSD	ICGC;COSMIC	56.683	Up-regulation
CAMK_CAMKL_AMPK_PRKAA1_ST	P29474	NOS3	Q13131	PRKAA1	S634	R628W	628	Missense	distal	-6	no	61.470	56.658	EPSD	ICGC;COSMIC	56.683	Loss
CAMK_CAMKL_AMPK_PRKAA1_ST	P29474	NOS3	Q13131	PRKAA1	T785	R782C	782	Missense	distal	-3	no	60.258	46.110	EPSD	ICGC;COSMIC	56.683	Loss
CAMK_CAMKL_AMPK_PRKAA1_ST	P29474	NOS3	Q13131	PRKAA1	T785	Q792P	792	Missense	distal	7	no	60.258	58.982	EPSD	ICGC;COSMIC	56.683	Down-regulation
CAMK_CAMKL_AMPK_PRKAA1_ST	P29474	NOS3	Q13131	PRKAA1	S870	S867F	867	Missense	distal	-3	no	61.669	61.817	EPSD	ICGC	56.683	Up-regulation
CAMK_CAMKL_AMPK_PRKAA1_ST	P29474	NOS3	Q13131	PRKAA1	S1177	Q1184H	1184	Missense	distal	7	no	71.268	69.177	PhosphoSitePlus;EPSD	ICGC;COSMIC	56.683	Down-regulation
CAMK_CAMKL_AMPK_PRKAA1_ST	P29474	NOS3	Q13131	PRKAA1	S1177	Q1176E	1176	Missense	proximal	-1	no	71.268	71.191	PhosphoSitePlus;EPSD	ICGC;COSMIC	56.683	Down-regulation
CAMK_CAMKL_AMPK_PRKAA1_ST	P29474	NOS3	Q13131	PRKAA1	S1179	Q1184H	1184	Missense	distal	5	no	63.880	63.642	EPSD	ICGC;COSMIC	56.683	Down-regulation
CAMK_CAMKL_AMPK_PRKAA1_ST	P29474	NOS3	Q13131	PRKAA1	S1179	Q1176E	1176	Missense	distal	-3	no	63.880	63.343	EPSD	ICGC;COSMIC	56.683	Down-regulation
CAMK_CAMKL_AMPK_PRKAA1_ST	P29474	NOS3	Q13131	PRKAA1	S1198	D1199H	1199	Missense	proximal	1	no	57.967	60.817	EPSD	ICGC	56.683	Up-regulation
CAMK_CAMKL_AMPK_PRKAA1_ST	P29474	NOS3	Q13131	PRKAA1	S1198	D1194N	1194	Missense	distal	-4	no	57.967	52.197	EPSD	ICGC;COSMIC	56.683	Loss
CAMK_CAMKL_AMPK_PRKAA1_ST	P50552	VASP	Q13131	PRKAA1	S134	S128L	128	Missense	distal	-6	no	60.421	60.732	EPSD	ICGC;COSMIC	56.683	Up-regulation
CAMK_CAMKL_AMPK_PRKAA1_ST	P50552	VASP	Q13131	PRKAA1	S134	W127C	127	Missense	distal	-7	no	60.421	57.230	EPSD	ICGC;COSMIC	56.683	Down-regulation
CAMK_CAMKL_AMPK_PRKAA1_ST	P50552	VASP	Q13131	PRKAA1	S134	P135Q	135	Missense	proximal	1	no	60.421	59.187	EPSD	ICGC;COSMIC	56.683	Down-regulation
CAMK_CAMKL_AMPK_PRKAA1_ST	P50552	VASP	Q13131	PRKAA1	S157	A164S	164	Missense	distal	7	no	63.922	63.794	EPSD	ICGC	56.683	Down-regulation
CAMK_CAMKL_AMPK_PRKAA1_ST	P50552	VASP	Q13131	PRKAA1	S157	V156F	156	Missense	proximal	-1	no	63.922	63.945	EPSD	ICGC	56.683	Up-regulation
CAMK_CAMKL_AMPK_PRKAA1_ST	P50552	VASP	Q13131	PRKAA1	S157	I152M	152	Missense	distal	-5	no	63.922	63.176	EPSD	ICGC;COSMIC	56.683	Down-regulation
CAMK_CAMKL_AMPK_PRKAA1_ST	P50552	VASP	Q13131	PRKAA1	S157	S157Y	157	Missense	central	0	yes	63.922	0.000	EPSD	ICGC;COSMIC	56.683	Loss
CAMK_CAMKL_AMPK_PRKAA1_ST	P50552	VASP	Q13131	PRKAA1	T278	P285H	285	Missense	distal	7	no	60.929	60.114	PhosphoSitePlus	ICGC;COSMIC	56.683	Down-regulation
CAMK_CAMKL_AMPK_PRKAA1_ST	P50552	VASP	Q13131	PRKAA1	T278	G281V	281	Missense	distal	3	no	60.929	60.624	PhosphoSitePlus	ICGC;COSMIC	56.683	Down-regulation
CAMK_CAMKL_AMPK_PRKAA1_ST	P50552	VASP	Q13131	PRKAA1	S303	P300Q	300	Missense	distal	-3	no	56.685	57.600	EPSD	ICGC;COSMIC	56.683	Up-regulation
CAMK_CAMKL_AMPK_PRKAA1_ST	P50552	VASP	Q13131	PRKAA1	S322	K321N	321	Missense	proximal	-1	no	67.825	67.891	EPSD	ICGC	56.683	Up-regulation
CAMK_CAMKL_AMPK_PRKAA1_ST	P50552	VASP	Q13131	PRKAA1	S338	T331A	331	Missense	distal	-7	no	58.626	57.776	EPSD	ICGC	56.683	Down-regulation
CAMK_CAMKL_AMPK_PRKAA1_ST	P50552	VASP	Q13131	PRKAA1	S338	C334F	334	Missense	distal	-4	no	58.626	51.403	EPSD	ICGC	56.683	Loss
CAMK_CAMKL_AMPK_PRKAA1_ST	Q13085	ACACA	Q13131	PRKAA1	S78	S78G	78	Missense	central	0	yes	63.524	0.000	EPSD	ICGC	56.683	Loss
CAMK_CAMKL_AMPK_PRKAA1_ST	Q13085	ACACA	Q13131	PRKAA1	S78	S78I	78	Missense	central	0	yes	63.524	0.000	EPSD	ICGC	56.683	Loss
CAMK_CAMKL_AMPK_PRKAA1_ST	Q13085	ACACA	Q13131	PRKAA1	S80	S78G	78	Missense	proximal	-2	no	63.057	59.752	PhosphoSitePlus	ICGC	56.683	Down-regulation
CAMK_CAMKL_AMPK_PRKAA1_ST	Q13085	ACACA	Q13131	PRKAA1	S80	S78I	78	Missense	proximal	-2	no	63.057	61.180	PhosphoSitePlus	ICGC	56.683	Down-regulation
CAMK_CAMKL_AMPK_PRKAA1_ST	Q13085	ACACA	Q13131	PRKAA1	S96	A103V	103	Missense	distal	7	no	58.565	56.147	EPSD	ICGC	56.683	Loss
CAMK_CAMKL_AMPK_PRKAA1_ST	Q13085	ACACA	Q13131	PRKAA1	S96	R91K	91	Missense	distal	-5	no	58.565	55.475	EPSD	ICGC	56.683	Loss
CAMK_CAMKL_AMPK_PRKAA1_ST	Q13085	ACACA	Q13131	PRKAA1	S835	G834D	834	Missense	proximal	-1	no	58.870	58.865	EPSD	ICGC	56.683	Down-regulation
CAMK_CAMKL_AMPK_PRKAA1_ST	Q13085	ACACA	Q13131	PRKAA1	S841	G834D	834	Missense	distal	-7	no	62.915	61.611	EPSD	ICGC	56.683	Down-regulation
CAMK_CAMKL_AMPK_PRKAA1_ST	Q13085	ACACA	Q13131	PRKAA1	S977	R980L	980	Missense	distal	3	no	67.169	65.837	EPSD	ICGC	56.683	Down-regulation
CAMK_CAMKL_AMPK_PRKAA1_ST	Q13085	ACACA	Q13131	PRKAA1	S977	R980Q	980	Missense	distal	3	no	67.169	68.563	EPSD	ICGC;CCLE	56.683	Up-regulation
CAMK_CAMKL_AMPK_PRKAA1_ST	Q9UQK1	PPP1R3C	Q13131	PRKAA1	T170	K176R	176	Missense	distal	6	no	70.453	70.401	EPSD	ICGC;COSMIC	56.683	Down-regulation
CAMK_CAMKL_AMPK_PRKAA1_ST	Q9UQK1	PPP1R3C	Q13131	PRKAA1	S293	I290M	290	Missense	distal	-3	no	57.511	58.027	PhosphoSitePlus;EPSD	ICGC;COSMIC	56.683	Up-regulation
CAMK_CAMKL_AMPK_PRKAA1_ST	P23458	JAK1	Q13131	PRKAA1	S228	S228F	228	Missense	central	0	yes	57.763	0.000	EPSD	ICGC;COSMIC	56.683	Loss
CAMK_CAMKL_AMPK_PRKAA1_ST	P23458	JAK1	Q13131	PRKAA1	S228	K227E	227	Missense	proximal	-1	no	57.763	57.789	EPSD	ICGC;COSMIC	56.683	Up-regulation
CAMK_CAMKL_AMPK_PRKAA1_ST	P23458	JAK1	Q13131	PRKAA1	S228	P222S	222	Missense	distal	-6	no	57.763	57.413	EPSD	ICGC;COSMIC	56.683	Down-regulation
CAMK_CAMKL_AMPK_PRKAA1_ST	P23458	JAK1	Q13131	PRKAA1	S398	H399N	399	Missense	proximal	1	no	63.125	60.260	EPSD	ICGC	56.683	Down-regulation
CAMK_CAMKL_AMPK_PRKAA1_ST	P23458	JAK1	Q13131	PRKAA1	S398	H399Q	399	Missense	proximal	1	no	63.125	59.247	EPSD	ICGC	56.683	Down-regulation
CAMK_CAMKL_AMPK_PRKAA1_ST	P23458	JAK1	Q13131	PRKAA1	S398	E401D	401	Missense	distal	3	no	63.125	64.834	EPSD	ICGC;COSMIC	56.683	Up-regulation
CAMK_CAMKL_AMPK_PRKAA1_ST	P23458	JAK1	Q13131	PRKAA1	S515	H510Q	510	Missense	distal	-5	no	65.849	65.547	EPSD;PhosphoSitePlus	ICGC	56.683	Down-regulation
CAMK_CAMKL_AMPK_PRKAA1_ST	P23458	JAK1	Q13131	PRKAA1	S515	P517H	517	Missense	proximal	2	no	65.849	65.694	EPSD;PhosphoSitePlus	ICGC;COSMIC	56.683	Down-regulation
CAMK_CAMKL_AMPK_PRKAA1_ST	P23458	JAK1	Q13131	PRKAA1	S515	G511D	511	Missense	distal	-4	no	65.849	69.362	EPSD;PhosphoSitePlus	ICGC;CCLE	56.683	Up-regulation
CAMK_CAMKL_AMPK_PRKAA1_ST	P23458	JAK1	Q13131	PRKAA1	S518	P517H	517	Missense	proximal	-1	no	58.438	58.470	PhosphoSitePlus;EPSD	ICGC;COSMIC	56.683	Up-regulation
CAMK_CAMKL_AMPK_PRKAA1_ST	P23458	JAK1	Q13131	PRKAA1	S518	G511D	511	Missense	distal	-7	no	58.438	57.133	PhosphoSitePlus;EPSD	ICGC;CCLE	56.683	Down-regulation
CAMK_CAMKL_AMPK_PRKAA1_ST	P23458	JAK1	Q13131	PRKAA1	T687	R681W	681	Missense	distal	-6	no	59.014	54.202	EPSD	ICGC;COSMIC;GDSC;CCLE	56.683	Loss
CAMK_CAMKL_AMPK_PRKAA1_ST	P23458	JAK1	Q13131	PRKAA1	T687	P689Q	689	Missense	proximal	2	no	59.014	58.087	EPSD	ICGC	56.683	Down-regulation
CAMK_CAMKL_AMPK_PRKAA1_ST	P23458	JAK1	Q13131	PRKAA1	T1100	T1100K	1100	Missense	central	0	yes	58.087	0.000	EPSD	ICGC;COSMIC	56.683	Loss
CAMK_CAMKL_AMPK_PRKAA1_ST	P46937	YAP1	Q13131	PRKAA1	S94	P99Q	99	Missense	distal	5	no	60.995	61.037	EPSD;PhosphoSitePlus	ICGC;COSMIC	56.683	Up-regulation
CAMK_CAMKL_AMPK_PRKAA1_ST	P46937	YAP1	Q13131	PRKAA1	S109	T110S	110	Missense	proximal	1	no	59.066	60.109	EPSD	ICGC;COSMIC	56.683	Up-regulation
CAMK_CAMKL_AMPK_PRKAA1_ST	P46937	YAP1	Q13131	PRKAA1	S109	A115T	115	Missense	distal	6	no	59.066	58.907	EPSD	ICGC	56.683	Down-regulation
CAMK_CAMKL_AMPK_PRKAA1_ST	P46937	YAP1	Q13131	PRKAA1	T110	A117S	117	Missense	distal	7	no	56.736	56.608	EPSD	ICGC	56.683	Loss
CAMK_CAMKL_AMPK_PRKAA1_ST	P46937	YAP1	Q13131	PRKAA1	S229	G230V	230	Missense	proximal	1	no	57.527	56.804	EPSD	ICGC;COSMIC	56.683	Down-regulation
CAMK_CAMKL_AMPK_PRKAA1_ST	P46937	YAP1	Q13131	PRKAA1	S229	L232H	232	Missense	distal	3	no	57.527	55.290	EPSD	ICGC	56.683	Loss
CAMK_CAMKL_AMPK_PRKAA1_ST	P46937	YAP1	Q13131	PRKAA1	S366	Q372R	372	Missense	distal	6	no	61.578	61.149	EPSD	ICGC;COSMIC	56.683	Down-regulation
CAMK_CAMKL_AMPK_PRKAA1_ST	P46937	YAP1	Q13131	PRKAA1	S366	G359C	359	Missense	distal	-7	no	61.578	58.770	EPSD	ICGC	56.683	Down-regulation
CAMK_CAMKL_AMPK_PRKAA1_ST	P46937	YAP1	Q13131	PRKAA1	S366	G369W	369	Missense	distal	3	no	61.578	61.783	EPSD	ICGC;COSMIC	56.683	Up-regulation
CAMK_CAMKL_AMPK_PRKAA1_ST	P46937	YAP1	Q13131	PRKAA1	S366	Q372K	372	Missense	distal	6	no	61.578	61.200	EPSD	ICGC;COSMIC	56.683	Down-regulation
CAMK_CAMKL_AMPK_PRKAA1_ST	P46937	YAP1	Q13131	PRKAA1	T378	Q372R	372	Missense	distal	-6	no	66.144	65.786	EPSD	ICGC;COSMIC	56.683	Down-regulation
CAMK_CAMKL_AMPK_PRKAA1_ST	P46937	YAP1	Q13131	PRKAA1	T378	F385S	385	Missense	distal	7	no	66.144	67.412	EPSD	ICGC	56.683	Up-regulation
CAMK_CAMKL_AMPK_PRKAA1_ST	P46937	YAP1	Q13131	PRKAA1	T378	Q372K	372	Missense	distal	-6	no	66.144	64.305	EPSD	ICGC;COSMIC	56.683	Down-regulation
CAMK_CAMKL_AMPK_PRKAA1_ST	P46937	YAP1	Q13131	PRKAA1	S382	F385S	385	Missense	distal	3	no	61.508	62.716	EPSD	ICGC	56.683	Up-regulation
CAMK_CAMKL_AMPK_PRKAA1_ST	P46937	YAP1	Q13131	PRKAA1	T390	R394Q	394	Missense	distal	4	no	57.287	53.204	EPSD	ICGC;COSMIC	56.683	Loss
CAMK_CAMKL_AMPK_PRKAA1_ST	P46937	YAP1	Q13131	PRKAA1	T390	S397I	397	Missense	distal	7	no	57.287	56.195	EPSD	ICGC	56.683	Loss
CAMK_CAMKL_AMPK_PRKAA1_ST	P46937	YAP1	Q13131	PRKAA1	T390	F385S	385	Missense	distal	-5	no	57.287	58.629	EPSD	ICGC	56.683	Up-regulation
CAMK_CAMKL_AMPK_PRKAA1_ST	P46937	YAP1	Q13131	PRKAA1	T390	H392N	392	Missense	proximal	2	no	57.287	56.654	EPSD	ICGC;COSMIC	56.683	Loss
CAMK_CAMKL_AMPK_PRKAA1_ST	P46937	YAP1	Q13131	PRKAA1	S400	L402P	402	Missense	proximal	2	no	56.299	56.899	EPSD	ICGC;COSMIC	56.683	Gain
CAMK_CAMKL_AMPK_PRKAA1_ST	P46937	YAP1	Q13131	PRKAA1	S400	T398A	398	Missense	proximal	-2	no	56.299	56.957	EPSD	ICGC;COSMIC	56.683	Gain
CAMK_CAMKL_AMPK_PRKAA1_ST	P46937	YAP1	Q13131	PRKAA1	S406	L402P	402	Missense	distal	-4	no	61.336	61.588	EPSD	ICGC;COSMIC	56.683	Up-regulation
CAMK_CAMKL_AMPK_PRKAA1_ST	P46937	YAP1	Q13131	PRKAA1	S406	V409F	409	Missense	distal	3	no	61.336	59.231	EPSD	ICGC	56.683	Down-regulation
CAMK_CAMKL_AMPK_PRKAA1_ST	P46937	YAP1	Q13131	PRKAA1	T412	V409F	409	Missense	distal	-3	no	57.206	56.374	EPSD	ICGC	56.683	Loss
CAMK_CAMKL_AMPK_PRKAA1_ST	P46937	YAP1	Q13131	PRKAA1	S499	T493A	493	Missense	distal	-6	no	57.882	58.084	EPSD	ICGC;COSMIC	56.683	Up-regulation
CAMK_CAMKL_AMPK_PRKAA1_ST	Q9H0B6	KLC2	Q13131	PRKAA1	T163	P160S	160	Missense	distal	-3	no	67.657	67.122	EPSD	ICGC;COSMIC	56.683	Down-regulation
CAMK_CAMKL_AMPK_PRKAA1_ST	Q9H0B6	KLC2	Q13131	PRKAA1	S445	C441F	441	Missense	distal	-4	no	61.611	54.389	EPSD	ICGC;COSMIC	56.683	Loss
CAMK_CAMKL_AMPK_PRKAA1_ST	Q9H0B6	KLC2	Q13131	PRKAA1	S487	Q481H	481	Missense	distal	-6	no	56.829	54.937	EPSD	ICGC;COSMIC	56.683	Loss
CAMK_CAMKL_AMPK_PRKAA1_ST	Q9H0B6	KLC2	Q13131	PRKAA1	S499	R502Q	502	Missense	distal	3	no	59.269	60.663	EPSD	ICGC;COSMIC	56.683	Up-regulation
CAMK_CAMKL_AMPK_PRKAA1_ST	Q9H0B6	KLC2	Q13131	PRKAA1	S499	R502W	502	Missense	distal	3	no	59.269	61.327	EPSD	ICGC;COSMIC	56.683	Up-regulation
CAMK_CAMKL_AMPK_PRKAA1_ST	Q9H0B6	KLC2	Q13131	PRKAA1	S545	R550Q	550	Missense	distal	5	no	79.895	79.941	PhosphoSitePlus;EPSD	ICGC;COSMIC	56.683	Up-regulation
CAMK_CAMKL_AMPK_PRKAA1_ST	Q9H0B6	KLC2	Q13131	PRKAA1	S557	R550Q	550	Missense	distal	-7	no	62.084	62.261	EPSD	ICGC;COSMIC	56.683	Up-regulation
CAMK_CAMKL_AMPK_PRKAA1_ST	Q9H0B6	KLC2	Q13131	PRKAA1	S581	R579L	579	Missense	proximal	-2	no	59.791	58.604	EPSD	ICGC;COSMIC	56.683	Down-regulation
CAMK_CAMKL_AMPK_PRKAA1_ST	Q9H0B6	KLC2	Q13131	PRKAA1	S582	R579L	579	Missense	distal	-3	no	66.356	56.390	EPSD;PhosphoSitePlus	ICGC;COSMIC	56.683	Loss
CAMK_CAMKL_AMPK_PRKAA1_ST	P09874	PARP1	Q13131	PRKAA1	S25	K22R	22	Missense	distal	-3	no	54.568	59.209	EPSD	ICGC;COSMIC	56.683	Gain
CAMK_CAMKL_AMPK_PRKAA1_ST	P09874	PARP1	Q13131	PRKAA1	S204	K207R	207	Missense	distal	3	no	61.071	59.665	EPSD	ICGC	56.683	Down-regulation
CAMK_CAMKL_AMPK_PRKAA1_ST	P09874	PARP1	Q13131	PRKAA1	S299	E296V	296	Missense	distal	-3	no	58.219	58.286	EPSD	ICGC;COSMIC	56.683	Up-regulation
CAMK_CAMKL_AMPK_PRKAA1_ST	P09874	PARP1	Q13131	PRKAA1	S299	S299L	299	Missense	central	0	yes	58.219	0.000	EPSD	ICGC	56.683	Loss
CAMK_CAMKL_AMPK_PRKAA1_ST	P09874	PARP1	Q13131	PRKAA1	S343	E341Q	341	Missense	proximal	-2	no	60.884	61.243	EPSD	ICGC	56.683	Up-regulation
CAMK_CAMKL_AMPK_PRKAA1_ST	P09874	PARP1	Q13131	PRKAA1	S343	R340Q	340	Missense	distal	-3	no	60.884	52.939	EPSD	ICGC;COSMIC	56.683	Loss
CAMK_CAMKL_AMPK_PRKAA1_ST	P09874	PARP1	Q13131	PRKAA1	S343	L345R	345	Missense	proximal	2	no	60.884	61.034	EPSD	ICGC;COSMIC	56.683	Up-regulation
CAMK_CAMKL_AMPK_PRKAA1_ST	P09874	PARP1	Q13131	PRKAA1	T361	T368K	368	Missense	distal	7	no	60.148	58.921	EPSD	ICGC	56.683	Down-regulation
CAMK_CAMKL_AMPK_PRKAA1_ST	P09874	PARP1	Q13131	PRKAA1	S391	P389T	389	Missense	proximal	-2	no	68.290	65.059	EPSD	ICGC	56.683	Down-regulation
CAMK_CAMKL_AMPK_PRKAA1_ST	P09874	PARP1	Q13131	PRKAA1	S465	D461G	461	Missense	distal	-4	no	59.342	55.828	EPSD	ICGC;COSMIC	56.683	Loss
CAMK_CAMKL_AMPK_PRKAA1_ST	P09874	PARP1	Q13131	PRKAA1	S499	A502V	502	Missense	distal	3	no	53.067	57.943	EPSD	ICGC;COSMIC;GDSC	56.683	Gain
CAMK_CAMKL_AMPK_PRKAA1_ST	P09874	PARP1	Q13131	PRKAA1	S507	A502V	502	Missense	distal	-5	no	61.478	60.286	EPSD	ICGC;COSMIC;GDSC	56.683	Down-regulation
CAMK_CAMKL_AMPK_PRKAA1_ST	P09874	PARP1	Q13131	PRKAA1	S507	G500W	500	Missense	distal	-7	no	61.478	61.862	EPSD	ICGC;COSMIC	56.683	Up-regulation
CAMK_CAMKL_AMPK_PRKAA1_ST	P09874	PARP1	Q13131	PRKAA1	S606	E612G	612	Missense	distal	6	no	58.313	57.912	EPSD	ICGC;COSMIC	56.683	Down-regulation
CAMK_CAMKL_AMPK_PRKAA1_ST	P09874	PARP1	Q13131	PRKAA1	S606	Q603K	603	Missense	distal	-3	no	58.313	61.616	EPSD	ICGC	56.683	Up-regulation
CAMK_CAMKL_AMPK_PRKAA1_ST	P09874	PARP1	Q13131	PRKAA1	S606	A610D	610	Missense	distal	4	no	58.313	55.519	EPSD	ICGC	56.683	Loss
CAMK_CAMKL_AMPK_PRKAA1_ST	P09874	PARP1	Q13131	PRKAA1	S606	H613Q	613	Missense	distal	7	no	58.313	60.404	EPSD	ICGC	56.683	Up-regulation
CAMK_CAMKL_AMPK_PRKAA1_ST	P09874	PARP1	Q13131	PRKAA1	S606	P605S	605	Missense	proximal	-1	no	58.313	58.358	EPSD	ICGC;COSMIC	56.683	Up-regulation
CAMK_CAMKL_AMPK_PRKAA1_ST	P09874	PARP1	Q13131	PRKAA1	S681	D678H	678	Missense	distal	-3	no	69.737	71.733	EPSD	ICGC;COSMIC	56.683	Up-regulation
CAMK_CAMKL_AMPK_PRKAA1_ST	P52292	KPNA2	Q13131	PRKAA1	T25	R29L	29	Missense	distal	4	no	52.660	58.142	EPSD	ICGC	56.683	Gain
CAMK_CAMKL_AMPK_PRKAA1_ST	P52292	KPNA2	Q13131	PRKAA1	S54	N52I	52	Missense	proximal	-2	no	64.161	62.944	EPSD	ICGC;COSMIC	56.683	Down-regulation
CAMK_CAMKL_AMPK_PRKAA1_ST	P52292	KPNA2	Q13131	PRKAA1	S55	N52I	52	Missense	distal	-3	no	58.087	50.625	EPSD	ICGC;COSMIC	56.683	Loss
CAMK_CAMKL_AMPK_PRKAA1_ST	P52292	KPNA2	Q13131	PRKAA1	S105	R106K	106	Missense	proximal	1	no	57.175	58.041	PhosphoSitePlus	ICGC	56.683	Up-regulation
CAMK_CAMKL_AMPK_PRKAA1_ST	P52292	KPNA2	Q13131	PRKAA1	T232	R238L	238	Missense	distal	6	no	58.401	58.641	EPSD	ICGC;COSMIC	56.683	Up-regulation
CAMK_CAMKL_AMPK_PRKAA1_ST	P52292	KPNA2	Q13131	PRKAA1	T232	R238C	238	Missense	distal	6	no	58.401	58.731	EPSD	ICGC;COSMIC	56.683	Up-regulation
CAMK_CAMKL_AMPK_PRKAA1_ST	O00418	EEF2K	Q13131	PRKAA1	S70	S71F	71	Missense	proximal	1	no	53.183	57.723	EPSD	ICGC;COSMIC	56.683	Gain
CAMK_CAMKL_AMPK_PRKAA1_ST	O00418	EEF2K	Q13131	PRKAA1	S71	P75L	75	Missense	distal	4	no	52.779	59.518	EPSD	ICGC;COSMIC	56.683	Gain
CAMK_CAMKL_AMPK_PRKAA1_ST	O00418	EEF2K	Q13131	PRKAA1	S78	P75A	75	Missense	distal	-3	no	58.426	56.429	EPSD	ICGC;COSMIC	56.683	Loss
CAMK_CAMKL_AMPK_PRKAA1_ST	O00418	EEF2K	Q13131	PRKAA1	S78	P75L	75	Missense	distal	-3	no	58.426	57.319	EPSD	ICGC;COSMIC	56.683	Down-regulation
CAMK_CAMKL_AMPK_PRKAA1_ST	O00418	EEF2K	Q13131	PRKAA1	S78	S71F	71	Missense	distal	-7	no	58.426	55.833	EPSD	ICGC;COSMIC	56.683	Loss
CAMK_CAMKL_AMPK_PRKAA1_ST	O00418	EEF2K	Q13131	PRKAA1	S78	F79L	79	Missense	proximal	1	no	58.426	52.961	EPSD	ICGC	56.683	Loss
CAMK_CAMKL_AMPK_PRKAA1_ST	O00418	EEF2K	Q13131	PRKAA1	S359	Q361R	361	Missense	proximal	2	no	60.593	61.070	EPSD	ICGC	56.683	Up-regulation
CAMK_CAMKL_AMPK_PRKAA1_ST	O00418	EEF2K	Q13131	PRKAA1	S359	P360L	360	Missense	proximal	1	no	60.593	60.300	EPSD	ICGC	56.683	Down-regulation
CAMK_CAMKL_AMPK_PRKAA1_ST	O00418	EEF2K	Q13131	PRKAA1	S368	R369W	369	Missense	proximal	1	no	56.835	57.441	EPSD	ICGC	56.683	Up-regulation
CAMK_CAMKL_AMPK_PRKAA1_ST	O00418	EEF2K	Q13131	PRKAA1	S368	Q361R	361	Missense	distal	-7	no	56.835	56.659	EPSD	ICGC	56.683	Loss
CAMK_CAMKL_AMPK_PRKAA1_ST	O00418	EEF2K	Q13131	PRKAA1	S398	S404C	404	Missense	distal	6	no	62.228	62.452	PhosphoSitePlus	ICGC	56.683	Up-regulation
CAMK_CAMKL_AMPK_PRKAA1_ST	O00418	EEF2K	Q13131	PRKAA1	S462	R466W	466	Missense	distal	4	no	55.787	59.037	EPSD	ICGC;COSMIC	56.683	Gain
CAMK_CAMKL_AMPK_PRKAA1_ST	O00418	EEF2K	Q13131	PRKAA1	S462	R457L	457	Missense	distal	-5	no	55.787	56.964	EPSD	ICGC	56.683	Gain
CAMK_CAMKL_AMPK_PRKAA1_ST	O60825	PFKFB2	Q13131	PRKAA1	T52	A48S	48	Missense	distal	-4	no	59.424	59.824	EPSD	ICGC	56.683	Up-regulation
CAMK_CAMKL_AMPK_PRKAA1_ST	O60825	PFKFB2	Q13131	PRKAA1	S214	I219V	219	Missense	distal	5	no	57.521	57.503	EPSD	ICGC;GDSC;CCLE	56.683	Down-regulation
CAMK_CAMKL_AMPK_PRKAA1_ST	O60825	PFKFB2	Q13131	PRKAA1	T458	R463H	463	Missense	distal	5	no	57.719	57.526	EPSD	ICGC	56.683	Down-regulation
CAMK_CAMKL_AMPK_PRKAA1_ST	O60825	PFKFB2	Q13131	PRKAA1	T458	R463P	463	Missense	distal	5	no	57.719	57.723	EPSD	ICGC	56.683	Up-regulation
CAMK_CAMKL_AMPK_PRKAA1_ST	O60825	PFKFB2	Q13131	PRKAA1	S466	R463H	463	Missense	distal	-3	no	70.731	62.875	PhosphoSitePlus	ICGC	56.683	Down-regulation
CAMK_CAMKL_AMPK_PRKAA1_ST	O60825	PFKFB2	Q13131	PRKAA1	S466	R463P	463	Missense	distal	-3	no	70.731	61.872	PhosphoSitePlus	ICGC	56.683	Down-regulation
CAMK_CAMKL_AMPK_PRKAA1_ST	P13569	CFTR	Q13131	PRKAA1	S45	P41S	41	Missense	distal	-4	no	60.799	62.042	EPSD	ICGC;COSMIC	56.683	Up-regulation
CAMK_CAMKL_AMPK_PRKAA1_ST	P13569	CFTR	Q13131	PRKAA1	S256	S263P	263	Missense	distal	7	no	56.867	56.369	EPSD	ICGC;COSMIC	56.683	Loss
CAMK_CAMKL_AMPK_PRKAA1_ST	P13569	CFTR	Q13131	PRKAA1	S256	S256I	256	Missense	central	0	yes	56.867	0.000	EPSD	ICGC	56.683	Loss
CAMK_CAMKL_AMPK_PRKAA1_ST	P13569	CFTR	Q13131	PRKAA1	S466	G463D	463	Missense	distal	-3	no	57.751	56.934	EPSD	ICGC	56.683	Down-regulation
CAMK_CAMKL_AMPK_PRKAA1_ST	P13569	CFTR	Q13131	PRKAA1	S466	K464N	464	Missense	proximal	-2	no	57.751	56.953	EPSD	ICGC;COSMIC	56.683	Down-regulation
CAMK_CAMKL_AMPK_PRKAA1_ST	P13569	CFTR	Q13131	PRKAA1	S641	D648N	648	Missense	distal	7	no	55.955	57.476	EPSD	ICGC;COSMIC	56.683	Gain
CAMK_CAMKL_AMPK_PRKAA1_ST	P13569	CFTR	Q13131	PRKAA1	S712	I708V	708	Missense	distal	-4	no	58.167	59.573	EPSD	ICGC;COSMIC	56.683	Up-regulation
CAMK_CAMKL_AMPK_PRKAA1_ST	P13569	CFTR	Q13131	PRKAA1	S768	R764L	764	Missense	distal	-4	no	65.934	63.375	EPSD;PhosphoSitePlus	ICGC	56.683	Down-regulation
CAMK_CAMKL_AMPK_PRKAA1_ST	P13569	CFTR	Q13131	PRKAA1	S1248	L1243F	1243	Missense	distal	-5	no	65.680	60.156	EPSD	ICGC	56.683	Down-regulation
CAMK_CAMKL_AMPK_PRKAA1_ST	P22460	KCNA5	Q13131	PRKAA1	S127	R121C	121	Missense	distal	-6	no	57.242	53.166	EPSD	ICGC;COSMIC	56.683	Loss
CAMK_CAMKL_AMPK_PRKAA1_ST	P22460	KCNA5	Q13131	PRKAA1	S127	V122F	122	Missense	distal	-5	no	57.242	56.583	EPSD	ICGC	56.683	Loss
CAMK_CAMKL_AMPK_PRKAA1_ST	P22460	KCNA5	Q13131	PRKAA1	S127	R121L	121	Missense	distal	-6	no	57.242	57.082	EPSD	ICGC;COSMIC	56.683	Down-regulation
CAMK_CAMKL_AMPK_PRKAA1_ST	P22460	KCNA5	Q13131	PRKAA1	S557	G558E	558	Missense	proximal	1	no	59.359	57.721	EPSD	ICGC	56.683	Down-regulation
CAMK_CAMKL_AMPK_PRKAA1_ST	P22460	KCNA5	Q13131	PRKAA1	S575	G568W	568	Missense	distal	-7	no	65.857	66.240	EPSD	ICGC;COSMIC	56.683	Up-regulation
CAMK_CAMKL_AMPK_PRKAA1_ST	P22460	KCNA5	Q13131	PRKAA1	S575	A573S	573	Missense	proximal	-2	no	65.857	67.881	EPSD	ICGC	56.683	Up-regulation
CAMK_CAMKL_AMPK_PRKAA1_ST	P22460	KCNA5	Q13131	PRKAA1	S575	G568V	568	Missense	distal	-7	no	65.857	64.059	EPSD	ICGC;COSMIC	56.683	Down-regulation
CAMK_CAMKL_AMPK_PRKAA1_ST	P22460	KCNA5	Q13131	PRKAA1	S575	C581F	581	Missense	distal	6	no	65.857	65.898	EPSD	ICGC	56.683	Up-regulation
CAMK_CAMKL_AMPK_PRKAA1_ST	P22460	KCNA5	Q13131	PRKAA1	S575	A573T	573	Missense	proximal	-2	no	65.857	65.198	EPSD	ICGC	56.683	Down-regulation
CAMK_CAMKL_AMPK_PRKAA1_ST	P22460	KCNA5	Q13131	PRKAA1	S592	N587S	587	Missense	distal	-5	no	48.314	63.242	PhosphoSitePlus	ICGC;COSMIC	56.683	Gain
CAMK_CAMKL_AMPK_PRKAA1_ST	O43524	FOXO3	Q13131	PRKAA1	S30	S26C	26	Missense	distal	-4	no	62.267	67.642	EPSD;PhosphoSitePlus	ICGC;COSMIC	56.683	Up-regulation
CAMK_CAMKL_AMPK_PRKAA1_ST	O43524	FOXO3	Q13131	PRKAA1	T32	S26C	26	Missense	distal	-6	no	60.858	57.252	EPSD	ICGC;COSMIC	56.683	Down-regulation
CAMK_CAMKL_AMPK_PRKAA1_ST	O43524	FOXO3	Q13131	PRKAA1	S75	G80S	80	Missense	distal	5	no	56.886	56.930	EPSD	ICGC;COSMIC	56.683	Up-regulation
CAMK_CAMKL_AMPK_PRKAA1_ST	O43524	FOXO3	Q13131	PRKAA1	S161	T167I	167	Missense	distal	6	no	58.083	57.826	EPSD	ICGC;COSMIC	56.683	Down-regulation
CAMK_CAMKL_AMPK_PRKAA1_ST	O43524	FOXO3	Q13131	PRKAA1	S161	T167A	167	Missense	distal	6	no	58.083	58.242	EPSD	ICGC;COSMIC	56.683	Up-regulation
CAMK_CAMKL_AMPK_PRKAA1_ST	O43524	FOXO3	Q13131	PRKAA1	S161	R168S	168	Missense	distal	7	no	58.083	58.669	EPSD	ICGC;COSMIC	56.683	Up-regulation
CAMK_CAMKL_AMPK_PRKAA1_ST	O43524	FOXO3	Q13131	PRKAA1	S161	R168H	168	Missense	distal	7	no	58.083	57.356	EPSD	ICGC;COSMIC	56.683	Down-regulation
CAMK_CAMKL_AMPK_PRKAA1_ST	O43524	FOXO3	Q13131	PRKAA1	T179	P174L	174	Missense	distal	-5	no	61.281	66.021	EPSD;PhosphoSitePlus	ICGC;COSMIC	56.683	Up-regulation
CAMK_CAMKL_AMPK_PRKAA1_ST	O43524	FOXO3	Q13131	PRKAA1	T179	S172N	172	Missense	distal	-7	no	61.281	60.190	EPSD;PhosphoSitePlus	ICGC	56.683	Down-regulation
CAMK_CAMKL_AMPK_PRKAA1_ST	O43524	FOXO3	Q13131	PRKAA1	T179	P174T	174	Missense	distal	-5	no	61.281	60.358	EPSD;PhosphoSitePlus	ICGC;COSMIC	56.683	Down-regulation
CAMK_CAMKL_AMPK_PRKAA1_ST	O43524	FOXO3	Q13131	PRKAA1	T179	K176R	176	Missense	distal	-3	no	61.281	65.922	EPSD;PhosphoSitePlus	ICGC;COSMIC	56.683	Up-regulation
CAMK_CAMKL_AMPK_PRKAA1_ST	O43524	FOXO3	Q13131	PRKAA1	S202	G198C	198	Missense	distal	-4	no	49.047	56.965	EPSD	ICGC;COSMIC	56.683	Gain
CAMK_CAMKL_AMPK_PRKAA1_ST	O43524	FOXO3	Q13131	PRKAA1	S215	R211Q	211	Missense	distal	-4	no	61.885	60.417	EPSD	ICGC;COSMIC	56.683	Down-regulation
CAMK_CAMKL_AMPK_PRKAA1_ST	O43524	FOXO3	Q13131	PRKAA1	S215	R222Q	222	Missense	distal	7	no	61.885	63.249	EPSD	ICGC;COSMIC;CCLE	56.683	Up-regulation
CAMK_CAMKL_AMPK_PRKAA1_ST	O43524	FOXO3	Q13131	PRKAA1	S215	R222L	222	Missense	distal	7	no	61.885	62.513	EPSD	ICGC;COSMIC	56.683	Up-regulation
CAMK_CAMKL_AMPK_PRKAA1_ST	O43524	FOXO3	Q13131	PRKAA1	S215	R211W	211	Missense	distal	-4	no	61.885	53.222	EPSD	ICGC;COSMIC	56.683	Loss
CAMK_CAMKL_AMPK_PRKAA1_ST	O43524	FOXO3	Q13131	PRKAA1	S253	R249L	249	Missense	distal	-4	no	63.963	61.404	EPSD	ICGC;COSMIC	56.683	Down-regulation
CAMK_CAMKL_AMPK_PRKAA1_ST	O43524	FOXO3	Q13131	PRKAA1	T313	A317T	317	Missense	distal	4	no	69.035	66.466	EPSD	ICGC;COSMIC	56.683	Down-regulation
CAMK_CAMKL_AMPK_PRKAA1_ST	O43524	FOXO3	Q13131	PRKAA1	S399	D392N	392	Missense	distal	-7	no	57.857	57.651	EPSD;PhosphoSitePlus	ICGC;COSMIC	56.683	Down-regulation
CAMK_CAMKL_AMPK_PRKAA1_ST	O43524	FOXO3	Q13131	PRKAA1	S399	S399F	399	Missense	central	0	yes	57.857	0.000	EPSD;PhosphoSitePlus	ICGC	56.683	Loss
CAMK_CAMKL_AMPK_PRKAA1_ST	O43524	FOXO3	Q13131	PRKAA1	S413	P415L	415	Missense	proximal	2	no	72.932	72.333	EPSD;PhosphoSitePlus	ICGC;COSMIC;GDSC	56.683	Down-regulation
CAMK_CAMKL_AMPK_PRKAA1_ST	O43524	FOXO3	Q13131	PRKAA1	S413	G420S	420	Missense	distal	7	no	72.932	72.983	EPSD;PhosphoSitePlus	ICGC;COSMIC	56.683	Up-regulation
CAMK_CAMKL_AMPK_PRKAA1_ST	O43524	FOXO3	Q13131	PRKAA1	S413	F414L	414	Missense	proximal	1	no	72.932	67.467	EPSD;PhosphoSitePlus	ICGC	56.683	Down-regulation
CAMK_CAMKL_AMPK_PRKAA1_ST	O43524	FOXO3	Q13131	PRKAA1	S428	G424S	424	Missense	distal	-4	no	54.335	56.878	EPSD	ICGC;COSMIC	56.683	Gain
CAMK_CAMKL_AMPK_PRKAA1_ST	O43524	FOXO3	Q13131	PRKAA1	S555	R548C	548	Missense	distal	-7	no	67.996	66.604	EPSD;PhosphoSitePlus	ICGC;COSMIC	56.683	Down-regulation
CAMK_CAMKL_AMPK_PRKAA1_ST	O43524	FOXO3	Q13131	PRKAA1	S666	S669I	669	Missense	distal	3	no	58.441	56.064	EPSD	ICGC;COSMIC	56.683	Loss
CAMK_CAMKL_AMPK_PRKAA1_ST	P46527	CDKN1B	Q13131	PRKAA1	S83	Y89H	89	Missense	distal	6	no	58.576	58.488	EPSD	ICGC;COSMIC	56.683	Down-regulation
CAMK_CAMKL_AMPK_PRKAA1_ST	P46527	CDKN1B	Q13131	PRKAA1	S83	V79L	79	Missense	distal	-4	no	58.576	58.474	EPSD	ICGC;COSMIC	56.683	Down-regulation
CAMK_CAMKL_AMPK_PRKAA1_ST	P46527	CDKN1B	Q13131	PRKAA1	S83	E78K	78	Missense	distal	-5	no	58.576	55.928	EPSD	ICGC;COSMIC	56.683	Loss
CAMK_CAMKL_AMPK_PRKAA1_ST	P46527	CDKN1B	Q13131	PRKAA1	S140	S138W	138	Missense	proximal	-2	no	63.949	60.370	EPSD	ICGC	56.683	Down-regulation
CAMK_CAMKL_AMPK_PRKAA1_ST	P46527	CDKN1B	Q13131	PRKAA1	T157	Q163E	163	Missense	distal	6	no	57.685	57.535	EPSD	ICGC;COSMIC	56.683	Down-regulation
CAMK_CAMKL_AMPK_PRKAA1_ST	P46527	CDKN1B	Q13131	PRKAA1	T157	S160F	160	Missense	distal	3	no	57.685	56.477	EPSD	ICGC;COSMIC	56.683	Loss
CAMK_CAMKL_AMPK_PRKAA1_ST	P46527	CDKN1B	Q13131	PRKAA1	T157	T162I	162	Missense	distal	5	no	57.685	57.602	EPSD	ICGC;COSMIC	56.683	Down-regulation
CAMK_CAMKL_AMPK_PRKAA1_ST	P46527	CDKN1B	Q13131	PRKAA1	S175	G182C	182	Missense	distal	7	no	59.348	58.846	EPSD	ICGC	56.683	Down-regulation
CAMK_CAMKL_AMPK_PRKAA1_ST	P46527	CDKN1B	Q13131	PRKAA1	S175	G177V	177	Missense	proximal	2	no	59.348	60.803	EPSD	ICGC	56.683	Up-regulation
CAMK_CAMKL_AMPK_PRKAA1_ST	P46527	CDKN1B	Q13131	PRKAA1	S175	S178F	178	Missense	distal	3	no	59.348	58.140	EPSD	ICGC;COSMIC	56.683	Down-regulation
CAMK_CAMKL_AMPK_PRKAA1_ST	Q16576	RBBP7	Q13131	PRKAA1	S145	I139T	139	Missense	distal	-6	no	54.942	58.082	EPSD	ICGC;COSMIC	56.683	Gain
CAMK_CAMKL_AMPK_PRKAA1_ST	Q16576	RBBP7	Q13131	PRKAA1	T416	E419K	419	Missense	distal	3	no	57.678	59.403	EPSD	ICGC;COSMIC	56.683	Up-regulation
CAMK_CAMKL_AMPK_PRKAA1_ST	Q16576	RBBP7	Q13131	PRKAA1	T416	N409Y	409	Missense	distal	-7	no	57.678	56.631	EPSD	ICGC	56.683	Loss
CAMK_CAMKL_AMPK_PRKAA1_ST	Q16576	RBBP7	Q13131	PRKAA1	T416	E421A	421	Missense	distal	5	no	57.678	57.770	EPSD	ICGC;COSMIC	56.683	Up-regulation
CAMK_CAMKL_AMPK_PRKAA1_ST	Q16576	RBBP7	Q13131	PRKAA1	T416	G422E	422	Missense	distal	6	no	57.678	58.080	EPSD	ICGC;COSMIC	56.683	Up-regulation
CAMK_CAMKL_AMPK_PRKAA1_ST	Q16576	RBBP7	Q13131	PRKAA1	T416	S413A	413	Missense	distal	-3	no	57.678	56.216	EPSD	ICGC;COSMIC	56.683	Loss
CAMK_CAMKL_AMPK_PRKAA1_ST	P11908	PRPS2	Q13131	PRKAA1	S16	Q13R	13	Missense	distal	-3	no	52.569	60.514	EPSD	ICGC;COSMIC	56.683	Gain
CAMK_CAMKL_AMPK_PRKAA1_ST	P11908	PRPS2	Q13131	PRKAA1	S180	A175S	175	Missense	distal	-5	no	65.447	64.936	PhosphoSitePlus	ICGC;COSMIC	56.683	Down-regulation
CAMK_CAMKL_AMPK_PRKAA1_ST	P11908	PRPS2	Q13131	PRKAA1	S180	R177S	177	Missense	distal	-3	no	65.447	56.052	PhosphoSitePlus	ICGC;COSMIC	56.683	Loss
CAMK_CAMKL_AMPK_PRKAA1_ST	P11908	PRPS2	Q13131	PRKAA1	T272	A265S	265	Missense	distal	-7	no	58.767	61.470	EPSD	ICGC;COSMIC	56.683	Up-regulation
CAMK_CAMKL_AMPK_PRKAA1_ST	P11908	PRPS2	Q13131	PRKAA1	T272	D279N	279	Missense	distal	7	no	58.767	60.288	EPSD	ICGC;COSMIC	56.683	Up-regulation
CAMK_CAMKL_AMPK_PRKAA1_ST	P11908	PRPS2	Q13131	PRKAA1	T272	A268V	268	Missense	distal	-4	no	58.767	57.774	EPSD	ICGC;COSMIC	56.683	Down-regulation
CAMK_CAMKL_AMPK_PRKAA1_ST	P11908	PRPS2	Q13131	PRKAA1	T272	V269F	269	Missense	distal	-3	no	58.767	57.934	EPSD	ICGC;COSMIC	56.683	Down-regulation
CAMK_CAMKL_AMPK_PRKAA1_ST	P11908	PRPS2	Q13131	PRKAA1	T272	Q277E	277	Missense	distal	5	no	58.767	58.640	EPSD	ICGC;COSMIC	56.683	Down-regulation
CAMK_CAMKL_AMPK_PRKAA1_ST	P11908	PRPS2	Q13131	PRKAA1	T272	P276Q	276	Missense	distal	4	no	58.767	55.941	EPSD	ICGC;COSMIC	56.683	Loss
CAMK_CAMKL_AMPK_PRKAA1_ST	P11908	PRPS2	Q13131	PRKAA1	T272	N273D	273	Missense	proximal	1	no	58.767	58.781	EPSD	ICGC;COSMIC	56.683	Up-regulation
CAMK_CAMKL_AMPK_PRKAA1_ST	P11908	PRPS2	Q13131	PRKAA1	T272	F266S	266	Missense	distal	-6	no	58.767	58.664	EPSD	ICGC	56.683	Down-regulation
CAMK_CAMKL_AMPK_PRKAA1_ST	P11908	PRPS2	Q13131	PRKAA1	S308	G306V	306	Missense	proximal	-2	no	55.904	59.217	EPSD	ICGC;COSMIC	56.683	Gain
CAMK_CAMKL_AMPK_PRKAA1_ST	Q9BZL4	PPP1R12C	Q13131	PRKAA1	S336	A334V	334	Missense	proximal	-2	no	61.500	63.532	EPSD	ICGC;COSMIC	56.683	Up-regulation
CAMK_CAMKL_AMPK_PRKAA1_ST	Q9BZL4	PPP1R12C	Q13131	PRKAA1	S344	S349I	349	Missense	distal	5	no	61.934	61.897	EPSD	ICGC	56.683	Down-regulation
CAMK_CAMKL_AMPK_PRKAA1_ST	Q9BZL4	PPP1R12C	Q13131	PRKAA1	S355	S349I	349	Missense	distal	-6	no	58.388	55.714	EPSD	ICGC	56.683	Loss
CAMK_CAMKL_AMPK_PRKAA1_ST	Q9BZL4	PPP1R12C	Q13131	PRKAA1	S427	L431M	431	Missense	distal	4	no	61.052	58.476	EPSD	ICGC	56.683	Down-regulation
CAMK_CAMKL_AMPK_PRKAA1_ST	Q9BZL4	PPP1R12C	Q13131	PRKAA1	S427	G421D	421	Missense	distal	-6	no	61.052	63.931	EPSD	ICGC;COSMIC	56.683	Up-regulation
CAMK_CAMKL_AMPK_PRKAA1_ST	Q9BZL4	PPP1R12C	Q13131	PRKAA1	S452	L447M	447	Missense	distal	-5	no	66.941	66.773	PhosphoSitePlus	ICGC;COSMIC	56.683	Down-regulation
CAMK_CAMKL_AMPK_PRKAA1_ST	Q9BZL4	PPP1R12C	Q13131	PRKAA1	S452	L456M	456	Missense	distal	4	no	66.941	64.364	PhosphoSitePlus	ICGC	56.683	Down-regulation
CAMK_CAMKL_AMPK_PRKAA1_ST	Q9BZL4	PPP1R12C	Q13131	PRKAA1	S486	V484I	484	Missense	proximal	-2	no	57.188	55.303	EPSD	ICGC;COSMIC	56.683	Loss
CAMK_CAMKL_AMPK_PRKAA1_ST	Q9BZL4	PPP1R12C	Q13131	PRKAA1	S544	K547I	547	Missense	distal	3	no	57.037	53.904	EPSD	ICGC;COSMIC	56.683	Loss
CAMK_CAMKL_AMPK_PRKAA1_ST	Q9BZL4	PPP1R12C	Q13131	PRKAA1	S544	R551H	551	Missense	distal	7	no	57.037	56.310	EPSD	ICGC	56.683	Loss
CAMK_CAMKL_AMPK_PRKAA1_ST	Q9BZL4	PPP1R12C	Q13131	PRKAA1	S544	S550F	550	Missense	distal	6	no	57.037	57.302	EPSD	ICGC	56.683	Up-regulation
CAMK_CAMKL_AMPK_PRKAA1_ST	Q9BZL4	PPP1R12C	Q13131	PRKAA1	S559	T560I	560	Missense	proximal	1	no	63.273	62.737	EPSD	ICGC;COSMIC	56.683	Down-regulation
CAMK_CAMKL_AMPK_PRKAA1_ST	Q9BZL4	PPP1R12C	Q13131	PRKAA1	S757	R760H	760	Missense	distal	3	no	66.004	62.435	EPSD	ICGC;COSMIC;GDSC	56.683	Down-regulation
CAMK_CAMKL_AMPK_PRKAA1_ST	Q6TCH7	PAQR3	Q13131	PRKAA1	S101	A100V	100	Missense	proximal	-1	no	57.349	57.258	EPSD	ICGC;COSMIC	56.683	Down-regulation
CAMK_CAMKL_AMPK_PRKAA1_ST	P04637	TP53	Q13131	PRKAA1	S46	D48G	48	Missense	proximal	2	no	58.440	57.288	EPSD	ICGC;COSMIC	56.683	Down-regulation
CAMK_CAMKL_AMPK_PRKAA1_ST	P04637	TP53	Q13131	PRKAA1	S46	Q52K	52	Missense	distal	6	no	58.440	58.063	EPSD	ICGC	56.683	Down-regulation
CAMK_CAMKL_AMPK_PRKAA1_ST	P04637	TP53	Q13131	PRKAA1	S106	Q100K	100	Missense	distal	-6	no	57.242	55.403	EPSD	ICGC;COSMIC	56.683	Loss
CAMK_CAMKL_AMPK_PRKAA1_ST	P04637	TP53	Q13131	PRKAA1	S106	F113I	113	Missense	distal	7	no	57.242	57.418	EPSD	ICGC;COSMIC	56.683	Up-regulation
CAMK_CAMKL_AMPK_PRKAA1_ST	P04637	TP53	Q13131	PRKAA1	S106	G105A	105	Missense	proximal	-1	no	57.242	57.258	EPSD	ICGC;COSMIC	56.683	Up-regulation
CAMK_CAMKL_AMPK_PRKAA1_ST	P04637	TP53	Q13131	PRKAA1	T155	P152R	152	Missense	distal	-3	no	51.338	60.197	EPSD	ICGC;COSMIC	56.683	Gain
CAMK_CAMKL_AMPK_PRKAA1_ST	P04637	TP53	Q13131	PRKAA1	S269	A276V	276	Missense	distal	7	no	57.267	54.849	EPSD	ICGC;COSMIC	56.683	Loss
CAMK_CAMKL_AMPK_PRKAA1_ST	P04637	TP53	Q13131	PRKAA1	S269	V274A	274	Missense	distal	5	no	57.267	57.367	EPSD	ICGC;COSMIC	56.683	Up-regulation
CAMK_CAMKL_AMPK_PRKAA1_ST	P04637	TP53	Q13131	PRKAA1	S269	V272E	272	Missense	distal	3	no	57.267	55.401	EPSD	ICGC;COSMIC;CCLE	56.683	Loss
CAMK_CAMKL_AMPK_PRKAA1_ST	P04637	TP53	Q13131	PRKAA1	S269	L265T	265	Missense	distal	-4	no	57.267	57.506	EPSD	ICGC	56.683	Up-regulation
CAMK_CAMKL_AMPK_PRKAA1_ST	P04637	TP53	Q13131	PRKAA1	S269	N268I	268	Missense	proximal	-1	no	57.267	57.321	EPSD	ICGC;COSMIC;GDSC;CCLE	56.683	Up-regulation
CAMK_CAMKL_AMPK_PRKAA1_ST	P04637	TP53	Q13131	PRKAA1	S269	E271D	271	Missense	proximal	2	no	57.267	57.306	EPSD	ICGC;COSMIC	56.683	Up-regulation
CAMK_CAMKL_AMPK_PRKAA1_ST	P04637	TP53	Q13131	PRKAA1	S367	G374C	374	Missense	distal	7	no	60.689	60.186	EPSD	ICGC;COSMIC	56.683	Down-regulation
CAMK_CAMKL_AMPK_PRKAA1_ST	P04637	TP53	Q13131	PRKAA1	S378	T377P	377	Missense	proximal	-1	no	56.911	56.923	EPSD	ICGC;COSMIC	56.683	Up-regulation
CAMK_CAMKL_AMPK_PRKAA1_ST	P04637	TP53	Q13131	PRKAA1	S378	F385L	385	Missense	distal	7	no	56.911	58.221	EPSD	ICGC;COSMIC	56.683	Up-regulation
CAMK_CAMKL_AMPK_PRKAA1_ST	P04637	TP53	Q13131	PRKAA1	S378	G374C	374	Missense	distal	-4	no	56.911	64.830	EPSD	ICGC;COSMIC	56.683	Up-regulation
CAMK_CAMKL_AMPK_PRKAA1_ST	P04637	TP53	Q13131	PRKAA1	S378	R379S	379	Missense	proximal	1	no	56.911	57.898	EPSD	ICGC	56.683	Up-regulation
CAMK_CAMKL_AMPK_PRKAA1_ST	P04637	TP53	Q13131	PRKAA1	S378	R379C	379	Missense	proximal	1	no	56.911	57.236	EPSD	ICGC;COSMIC	56.683	Up-regulation
CAMK_CAMKL_AMPK_PRKAA1_ST	P00533	EGFR	Q13131	PRKAA1	T1150	H1156N	1156	Missense	distal	6	no	66.138	66.022	EPSD	ICGC;COSMIC	56.683	Down-regulation
CAMK_CAMKL_AMPK_PRKAA1_ST	P00533	EGFR	Q13131	PRKAA1	T1150	S1153I	1153	Missense	distal	3	no	66.138	63.761	EPSD	ICGC;COSMIC	56.683	Down-regulation
CAMK_CAMKL_AMPK_PRKAA1_ST	P00533	EGFR	Q13131	PRKAA1	T1150	F1151I	1151	Missense	proximal	1	no	66.138	60.019	EPSD	ICGC	56.683	Down-regulation
CAMK_CAMKL_AMPK_PRKAA1_ST	P00533	EGFR	Q13131	PRKAA1	T1150	S1153N	1153	Missense	distal	3	no	66.138	68.132	EPSD	ICGC;COSMIC	56.683	Up-regulation
CAMK_CAMKL_AMPK_PRKAA1_ST	P00533	EGFR	Q13131	PRKAA1	S1204	Y1197C	1197	Missense	distal	-7	no	62.597	62.347	EPSD	ICGC;COSMIC	56.683	Down-regulation
CAMK_CAMKL_AMPK_PRKAA1_ST	P00533	EGFR	Q13131	PRKAA1	S1204	L1198I	1198	Missense	distal	-6	no	62.597	59.613	EPSD	ICGC;COSMIC	56.683	Down-regulation
CAMK_CAMKL_AMPK_PRKAA1_ST	Q92538	GBF1	Q13131	PRKAA1	S302	Q299K	299	Missense	distal	-3	no	62.732	66.036	EPSD	ICGC;COSMIC	56.683	Up-regulation
CAMK_CAMKL_AMPK_PRKAA1_ST	Q92538	GBF1	Q13131	PRKAA1	S314	A320S	320	Missense	distal	6	no	64.829	64.736	EPSD	ICGC	56.683	Down-regulation
CAMK_CAMKL_AMPK_PRKAA1_ST	Q92538	GBF1	Q13131	PRKAA1	S314	P315L	315	Missense	proximal	1	no	64.829	64.536	EPSD	ICGC;COSMIC	56.683	Down-regulation
CAMK_CAMKL_AMPK_PRKAA1_ST	Q92538	GBF1	Q13131	PRKAA1	S325	A320S	320	Missense	distal	-5	no	56.706	56.195	EPSD	ICGC	56.683	Loss
CAMK_CAMKL_AMPK_PRKAA1_ST	Q92538	GBF1	Q13131	PRKAA1	S325	S325G	325	Missense	central	0	yes	56.706	0.000	EPSD	ICGC;COSMIC	56.683	Loss
CAMK_CAMKL_AMPK_PRKAA1_ST	Q92538	GBF1	Q13131	PRKAA1	S325	P323H	323	Missense	proximal	-2	no	56.706	52.196	EPSD	ICGC;COSMIC	56.683	Loss
CAMK_CAMKL_AMPK_PRKAA1_ST	Q92538	GBF1	Q13131	PRKAA1	S349	K344N	344	Missense	distal	-5	no	57.047	42.203	EPSD	ICGC;CCLE	56.683	Loss
CAMK_CAMKL_AMPK_PRKAA1_ST	Q92538	GBF1	Q13131	PRKAA1	S349	P354L	354	Missense	distal	5	no	57.047	57.040	EPSD	ICGC	56.683	Down-regulation
CAMK_CAMKL_AMPK_PRKAA1_ST	Q92538	GBF1	Q13131	PRKAA1	S670	A677T	677	Missense	distal	7	no	57.868	57.494	EPSD	ICGC;COSMIC	56.683	Down-regulation
CAMK_CAMKL_AMPK_PRKAA1_ST	Q92538	GBF1	Q13131	PRKAA1	S670	D673Y	673	Missense	distal	3	no	57.868	58.048	EPSD	ICGC;COSMIC	56.683	Up-regulation
CAMK_CAMKL_AMPK_PRKAA1_ST	Q92538	GBF1	Q13131	PRKAA1	S670	D673V	673	Missense	distal	3	no	57.868	58.025	EPSD	ICGC;COSMIC	56.683	Up-regulation
CAMK_CAMKL_AMPK_PRKAA1_ST	Q92538	GBF1	Q13131	PRKAA1	S670	D673N	673	Missense	distal	3	no	57.868	59.122	EPSD	ICGC;COSMIC	56.683	Up-regulation
CAMK_CAMKL_AMPK_PRKAA1_ST	Q92538	GBF1	Q13131	PRKAA1	S670	E665K	665	Missense	distal	-5	no	57.868	55.220	EPSD	ICGC;COSMIC	56.683	Loss
CAMK_CAMKL_AMPK_PRKAA1_ST	Q92538	GBF1	Q13131	PRKAA1	S670	E665D	665	Missense	distal	-5	no	57.868	54.452	EPSD	ICGC;COSMIC	56.683	Loss
CAMK_CAMKL_AMPK_PRKAA1_ST	Q92538	GBF1	Q13131	PRKAA1	S1298	P1303T	1303	Missense	distal	5	no	59.577	59.584	EPSD	ICGC;COSMIC	56.683	Up-regulation
CAMK_CAMKL_AMPK_PRKAA1_ST	Q92538	GBF1	Q13131	PRKAA1	S1298	G1295V	1295	Missense	distal	-3	no	59.577	60.198	EPSD	ICGC;COSMIC	56.683	Up-regulation
CAMK_CAMKL_AMPK_PRKAA1_ST	Q92538	GBF1	Q13131	PRKAA1	S1298	P1303Q	1303	Missense	distal	5	no	59.577	59.619	EPSD	ICGC;COSMIC	56.683	Up-regulation
CAMK_CAMKL_AMPK_PRKAA1_ST	Q92538	GBF1	Q13131	PRKAA1	S1304	P1303T	1303	Missense	proximal	-1	no	57.444	57.432	EPSD	ICGC;COSMIC	56.683	Down-regulation
CAMK_CAMKL_AMPK_PRKAA1_ST	Q92538	GBF1	Q13131	PRKAA1	S1304	P1303Q	1303	Missense	proximal	-1	no	57.444	57.485	EPSD	ICGC;COSMIC	56.683	Up-regulation
CAMK_CAMKL_AMPK_PRKAA1_ST	Q92538	GBF1	Q13131	PRKAA1	T1317	D1313A	1313	Missense	distal	-4	no	58.757	57.386	EPSD	ICGC;COSMIC	56.683	Down-regulation
CAMK_CAMKL_AMPK_PRKAA1_ST	Q92538	GBF1	Q13131	PRKAA1	S1444	R1448H	1448	Missense	distal	4	no	59.605	56.604	EPSD	ICGC;COSMIC	56.683	Loss
CAMK_CAMKL_AMPK_PRKAA1_ST	Q92538	GBF1	Q13131	PRKAA1	S1444	S1444I	1444	Missense	central	0	yes	59.605	0.000	EPSD	ICGC	56.683	Loss
CAMK_CAMKL_AMPK_PRKAA1_ST	Q92538	GBF1	Q13131	PRKAA1	S1444	S1439N	1439	Missense	distal	-5	no	59.605	44.677	EPSD	ICGC	56.683	Loss
CAMK_CAMKL_AMPK_PRKAA1_ST	Q92538	GBF1	Q13131	PRKAA1	S1453	R1460H	1460	Missense	distal	7	no	57.301	56.574	EPSD	ICGC	56.683	Loss
CAMK_CAMKL_AMPK_PRKAA1_ST	Q92538	GBF1	Q13131	PRKAA1	S1453	R1448H	1448	Missense	distal	-5	no	57.301	51.920	EPSD	ICGC;COSMIC	56.683	Loss
CAMK_CAMKL_AMPK_PRKAA1_ST	Q92538	GBF1	Q13131	PRKAA1	S1453	R1460L	1460	Missense	distal	7	no	57.301	57.929	EPSD	ICGC	56.683	Up-regulation
CAMK_CAMKL_AMPK_PRKAA1_ST	Q92538	GBF1	Q13131	PRKAA1	S1453	K1452R	1452	Missense	proximal	-1	no	57.301	57.374	EPSD	ICGC;COSMIC	56.683	Up-regulation
CAMK_CAMKL_AMPK_PRKAA1_ST	Q92538	GBF1	Q13131	PRKAA1	S1453	R1460C	1460	Missense	distal	7	no	57.301	57.334	EPSD	ICGC;COSMIC	56.683	Up-regulation
CAMK_CAMKL_AMPK_PRKAA1_ST	Q92538	GBF1	Q13131	PRKAA1	S1457	R1461Q	1461	Missense	distal	4	no	64.775	60.691	EPSD	ICGC	56.683	Down-regulation
CAMK_CAMKL_AMPK_PRKAA1_ST	Q92538	GBF1	Q13131	PRKAA1	S1457	R1460H	1460	Missense	distal	3	no	64.775	61.206	EPSD	ICGC	56.683	Down-regulation
CAMK_CAMKL_AMPK_PRKAA1_ST	Q92538	GBF1	Q13131	PRKAA1	S1457	R1460L	1460	Missense	distal	3	no	64.775	63.443	EPSD	ICGC	56.683	Down-regulation
CAMK_CAMKL_AMPK_PRKAA1_ST	Q92538	GBF1	Q13131	PRKAA1	S1457	K1452R	1452	Missense	distal	-5	no	64.775	67.864	EPSD	ICGC;COSMIC	56.683	Up-regulation
CAMK_CAMKL_AMPK_PRKAA1_ST	Q92538	GBF1	Q13131	PRKAA1	S1457	R1460C	1460	Missense	distal	3	no	64.775	63.594	EPSD	ICGC;COSMIC	56.683	Down-regulation
CAMK_CAMKL_AMPK_PRKAA1_ST	Q92538	GBF1	Q13131	PRKAA1	T1464	R1460C	1460	Missense	distal	-4	no	55.945	60.256	EPSD	ICGC;COSMIC	56.683	Gain
CAMK_CAMKL_AMPK_PRKAA1_ST	Q92538	GBF1	Q13131	PRKAA1	S1465	R1461Q	1461	Missense	distal	-4	no	59.588	58.120	EPSD	ICGC	56.683	Down-regulation
CAMK_CAMKL_AMPK_PRKAA1_ST	Q92538	GBF1	Q13131	PRKAA1	S1465	R1460H	1460	Missense	distal	-5	no	59.588	54.208	EPSD	ICGC	56.683	Loss
CAMK_CAMKL_AMPK_PRKAA1_ST	Q92538	GBF1	Q13131	PRKAA1	S1465	R1460L	1460	Missense	distal	-5	no	59.588	60.765	EPSD	ICGC	56.683	Up-regulation
CAMK_CAMKL_AMPK_PRKAA1_ST	Q92538	GBF1	Q13131	PRKAA1	S1465	Q1467K	1467	Missense	proximal	2	no	59.588	60.181	EPSD	ICGC;COSMIC	56.683	Up-regulation
CAMK_CAMKL_AMPK_PRKAA1_ST	Q92538	GBF1	Q13131	PRKAA1	S1465	R1460C	1460	Missense	distal	-5	no	59.588	58.235	EPSD	ICGC;COSMIC	56.683	Down-regulation
CAMK_CAMKL_AMPK_PRKAA1_ST	Q92538	GBF1	Q13131	PRKAA1	S1773	C1766R	1766	Missense	distal	-7	no	57.439	58.831	EPSD	ICGC;COSMIC	56.683	Up-regulation
CAMK_CAMKL_AMPK_PRKAA1_ST	P60891	PRPS1	Q13131	PRKAA1	T40	S36R	36	Missense	distal	-4	no	57.001	58.065	EPSD	ICGC	56.683	Up-regulation
CAMK_CAMKL_AMPK_PRKAA1_ST	P60891	PRPS1	Q13131	PRKAA1	T40	S36N	36	Missense	distal	-4	no	57.001	52.201	EPSD	ICGC	56.683	Loss
CAMK_CAMKL_AMPK_PRKAA1_ST	P60891	PRPS1	Q13131	PRKAA1	S180	G173D	173	Missense	distal	-7	no	66.721	65.417	PhosphoSitePlus	ICGC	56.683	Down-regulation
CAMK_CAMKL_AMPK_PRKAA1_ST	P19429	TNNI3	Q13131	PRKAA1	S23	R27S	27	Missense	distal	4	no	64.699	63.593	PhosphoSitePlus;EPSD	ICGC	56.683	Down-regulation
CAMK_CAMKL_AMPK_PRKAA1_ST	P19429	TNNI3	Q13131	PRKAA1	S23	R21S	21	Missense	proximal	-2	no	64.699	65.939	PhosphoSitePlus;EPSD	ICGC	56.683	Up-regulation
CAMK_CAMKL_AMPK_PRKAA1_ST	P19429	TNNI3	Q13131	PRKAA1	S23	S24F	24	Missense	proximal	1	no	64.699	69.239	PhosphoSitePlus;EPSD	ICGC;COSMIC	56.683	Up-regulation
CAMK_CAMKL_AMPK_PRKAA1_ST	P19429	TNNI3	Q13131	PRKAA1	S23	R21L	21	Missense	proximal	-2	no	64.699	63.513	PhosphoSitePlus;EPSD	ICGC;COSMIC	56.683	Down-regulation
CAMK_CAMKL_AMPK_PRKAA1_ST	P19429	TNNI3	Q13131	PRKAA1	S24	R27S	27	Missense	distal	3	no	67.603	68.253	EPSD;PhosphoSitePlus	ICGC	56.683	Up-regulation
CAMK_CAMKL_AMPK_PRKAA1_ST	P19429	TNNI3	Q13131	PRKAA1	S24	R21S	21	Missense	distal	-3	no	67.603	58.208	EPSD;PhosphoSitePlus	ICGC	56.683	Down-regulation
CAMK_CAMKL_AMPK_PRKAA1_ST	P19429	TNNI3	Q13131	PRKAA1	S24	S24F	24	Missense	central	0	yes	67.603	0.000	EPSD;PhosphoSitePlus	ICGC;COSMIC	56.683	Loss
CAMK_CAMKL_AMPK_PRKAA1_ST	P19429	TNNI3	Q13131	PRKAA1	S24	R21L	21	Missense	distal	-3	no	67.603	57.636	EPSD;PhosphoSitePlus	ICGC;COSMIC	56.683	Down-regulation
CAMK_CAMKL_AMPK_PRKAA1_ST	P19429	TNNI3	Q13131	PRKAA1	T119	A126E	126	Missense	distal	7	no	58.629	57.725	EPSD	ICGC;COSMIC	56.683	Down-regulation
CAMK_CAMKL_AMPK_PRKAA1_ST	P19429	TNNI3	Q13131	PRKAA1	S150	R145W	145	Missense	distal	-5	no	59.336	54.143	EPSD;PhosphoSitePlus	ICGC;COSMIC;GDSC;CCLE	56.683	Loss
CAMK_CAMKL_AMPK_PRKAA1_ST	Q14457	BECN1	Q13131	PRKAA1	T29	P24L	24	Missense	distal	-5	no	54.242	58.982	EPSD	ICGC	56.683	Gain
CAMK_CAMKL_AMPK_PRKAA1_ST	Q14457	BECN1	Q13131	PRKAA1	S90	P85Q	85	Missense	distal	-5	no	59.533	57.415	EPSD	ICGC	56.683	Down-regulation
CAMK_CAMKL_AMPK_PRKAA1_ST	Q14457	BECN1	Q13131	PRKAA1	S96	A103E	103	Missense	distal	7	no	58.267	57.362	EPSD;PhosphoSitePlus	ICGC	56.683	Down-regulation
CAMK_CAMKL_AMPK_PRKAA1_ST	Q14457	BECN1	Q13131	PRKAA1	S104	D105N	105	Missense	proximal	1	no	57.919	57.905	EPSD	ICGC	56.683	Down-regulation
CAMK_CAMKL_AMPK_PRKAA1_ST	Q14457	BECN1	Q13131	PRKAA1	S104	A103E	103	Missense	proximal	-1	no	57.919	57.817	EPSD	ICGC	56.683	Down-regulation
CAMK_CAMKL_AMPK_PRKAA1_ST	Q14457	BECN1	Q13131	PRKAA1	T108	D105N	105	Missense	distal	-3	no	59.691	63.607	EPSD	ICGC	56.683	Up-regulation
CAMK_CAMKL_AMPK_PRKAA1_ST	Q14457	BECN1	Q13131	PRKAA1	T108	A103E	103	Missense	distal	-5	no	59.691	61.743	EPSD	ICGC	56.683	Up-regulation
CAMK_CAMKL_AMPK_PRKAA1_ST	Q14457	BECN1	Q13131	PRKAA1	T108	S113R	113	Missense	distal	5	no	59.691	59.726	EPSD	ICGC	56.683	Up-regulation
CAMK_CAMKL_AMPK_PRKAA1_ST	Q14457	BECN1	Q13131	PRKAA1	S234	Q240K	240	Missense	distal	6	no	57.551	57.173	EPSD	ICGC	56.683	Down-regulation
CAMK_CAMKL_AMPK_PRKAA1_ST	Q14457	BECN1	Q13131	PRKAA1	S234	Q230H	230	Missense	distal	-4	no	57.551	55.633	EPSD	ICGC;COSMIC	56.683	Loss
CAMK_CAMKL_AMPK_PRKAA1_ST	Q14457	BECN1	Q13131	PRKAA1	T388	R389H	389	Missense	proximal	1	no	58.403	61.401	EPSD;PhosphoSitePlus	ICGC;COSMIC	56.683	Up-regulation
CAMK_CAMKL_AMPK_PRKAA1_ST	Q14457	BECN1	Q13131	PRKAA1	T388	L392I	392	Missense	distal	4	no	58.403	55.327	EPSD;PhosphoSitePlus	ICGC	56.683	Loss
CAMK_CAMKL_AMPK_PRKAA1_ST	Q14457	BECN1	Q13131	PRKAA1	T388	V383A	383	Missense	distal	-5	no	58.403	59.596	EPSD;PhosphoSitePlus	ICGC;COSMIC	56.683	Up-regulation
CAMK_CAMKL_AMPK_PRKAA1_ST	Q14457	BECN1	Q13131	PRKAA1	S421	I415M	415	Missense	distal	-6	no	54.960	56.793	EPSD	ICGC	56.683	Gain
CAMK_CAMKL_AMPK_PRKAA1_ST	Q8N122	RPTOR	Q13131	PRKAA1	S791	D785Y	785	Missense	distal	-6	no	62.734	57.851	EPSD	ICGC	56.683	Down-regulation
CAMK_CAMKL_AMPK_PRKAA1_ST	Q8N122	RPTOR	Q13131	PRKAA1	S792	D785Y	785	Missense	distal	-7	no	68.942	67.688	PhosphoSitePlus;EPSD	ICGC	56.683	Down-regulation
CAMK_CAMKL_AMPK_PRKAA1_ST	Q8N122	RPTOR	Q13131	PRKAA1	T908	A914V	914	Missense	distal	6	no	58.861	58.656	EPSD	ICGC;COSMIC	56.683	Down-regulation
CAMK_CAMKL_AMPK_PRKAA1_ST	Q13621	SLC12A1	Q13131	PRKAA1	S130	P124T	124	Missense	distal	-6	no	62.602	62.719	PhosphoSitePlus	ICGC;COSMIC	56.683	Up-regulation
CAMK_CAMKL_AMPK_PRKAA1_ST	Q13621	SLC12A1	Q13131	PRKAA1	S130	E133Q	133	Missense	distal	3	no	62.602	64.314	PhosphoSitePlus	ICGC	56.683	Up-regulation
CAMK_CAMKL_AMPK_PRKAA1_ST	Q13621	SLC12A1	Q13131	PRKAA1	S130	G123E	123	Missense	distal	-7	no	62.602	61.397	PhosphoSitePlus	ICGC	56.683	Down-regulation
CAMK_CAMKL_AMPK_PRKAA1_ST	Q13621	SLC12A1	Q13131	PRKAA1	S130	E136K	136	Missense	distal	6	no	62.602	62.374	PhosphoSitePlus	ICGC;COSMIC	56.683	Down-regulation
CAMK_CAMKL_AMPK_PRKAA1_ST	Q13621	SLC12A1	Q13131	PRKAA1	S1003	R999H	999	Missense	distal	-4	no	56.970	53.583	EPSD	ICGC;GDSC;CCLE	56.683	Loss
CAMK_CAMKL_AMPK_PRKAA1_ST	Q13621	SLC12A1	Q13131	PRKAA1	S1003	H1001Y	1001	Missense	proximal	-2	no	56.970	59.368	EPSD	ICGC;COSMIC	56.683	Up-regulation
CAMK_CAMKL_AMPK_PRKAA1_ST	O75925	PIAS1	Q13131	PRKAA1	T71	T71M	71	Missense	central	0	yes	59.434	0.000	EPSD	ICGC;COSMIC	56.683	Loss
CAMK_CAMKL_AMPK_PRKAA1_ST	O75925	PIAS1	Q13131	PRKAA1	T71	R64Q	64	Missense	distal	-7	no	59.434	59.611	EPSD	ICGC;COSMIC	56.683	Up-regulation
CAMK_CAMKL_AMPK_PRKAA1_ST	O75925	PIAS1	Q13131	PRKAA1	S155	S161N	161	Missense	distal	6	no	58.073	57.955	EPSD	ICGC;COSMIC	56.683	Down-regulation
CAMK_CAMKL_AMPK_PRKAA1_ST	O75925	PIAS1	Q13131	PRKAA1	S155	S155I	155	Missense	central	0	yes	58.073	0.000	EPSD	ICGC	56.683	Loss
CAMK_CAMKL_AMPK_PRKAA1_ST	O75925	PIAS1	Q13131	PRKAA1	S155	S155R	155	Missense	central	0	yes	58.073	0.000	EPSD	ICGC	56.683	Loss
CAMK_CAMKL_AMPK_PRKAA1_ST	O75925	PIAS1	Q13131	PRKAA1	S289	Y283H	283	Missense	distal	-6	no	64.633	66.068	EPSD	ICGC;COSMIC	56.683	Up-regulation
CAMK_CAMKL_AMPK_PRKAA1_ST	O75925	PIAS1	Q13131	PRKAA1	S289	V292F	292	Missense	distal	3	no	64.633	62.528	EPSD	ICGC	56.683	Down-regulation
CAMK_CAMKL_AMPK_PRKAA1_ST	O75925	PIAS1	Q13131	PRKAA1	S289	R296M	296	Missense	distal	7	no	64.633	63.257	EPSD	ICGC	56.683	Down-regulation
CAMK_CAMKL_AMPK_PRKAA1_ST	O75925	PIAS1	Q13131	PRKAA1	S476	R479G	479	Missense	distal	3	no	58.365	60.218	EPSD	ICGC;COSMIC	56.683	Up-regulation
CAMK_CAMKL_AMPK_PRKAA1_ST	O75925	PIAS1	Q13131	PRKAA1	S485	R479G	479	Missense	distal	-6	no	62.320	61.356	EPSD	ICGC;COSMIC	56.683	Down-regulation
CAMK_CAMKL_AMPK_PRKAA1_ST	O75925	PIAS1	Q13131	PRKAA1	S510	A513V	513	Missense	distal	3	no	64.495	69.372	PhosphoSitePlus	ICGC	56.683	Up-regulation
CAMK_CAMKL_AMPK_PRKAA1_ST	O75925	PIAS1	Q13131	PRKAA1	S510	V514L	514	Missense	distal	4	no	64.495	68.993	PhosphoSitePlus	ICGC;COSMIC	56.683	Up-regulation
CAMK_CAMKL_AMPK_PRKAA1_ST	O75925	PIAS1	Q13131	PRKAA1	S510	R507S	507	Missense	distal	-3	no	64.495	55.100	PhosphoSitePlus	ICGC;COSMIC	56.683	Loss
CAMK_CAMKL_AMPK_PRKAA1_ST	Q13362	PPP2R5C	Q13131	PRKAA1	S298	M303I	303	Missense	distal	5	no	59.027	59.135	PhosphoSitePlus;EPSD	ICGC	56.683	Up-regulation
CAMK_CAMKL_AMPK_PRKAA1_ST	Q13362	PPP2R5C	Q13131	PRKAA1	S298	P299S	299	Missense	proximal	1	no	59.027	59.660	PhosphoSitePlus;EPSD	ICGC;COSMIC	56.683	Up-regulation
CAMK_CAMKL_AMPK_PRKAA1_ST	Q13362	PPP2R5C	Q13131	PRKAA1	S336	S336Y	336	Missense	central	0	yes	63.363	0.000	EPSD;PhosphoSitePlus	ICGC;COSMIC	56.683	Loss
CAMK_CAMKL_AMPK_PRKAA1_ST	Q13362	PPP2R5C	Q13131	PRKAA1	S336	K333T	333	Missense	distal	-3	no	63.363	53.893	EPSD;PhosphoSitePlus	ICGC;COSMIC	56.683	Loss
CAMK_CAMKL_AMPK_PRKAA1_ST	Q13362	PPP2R5C	Q13131	PRKAA1	S336	S336F	336	Missense	central	0	yes	63.363	0.000	EPSD;PhosphoSitePlus	ICGC;COSMIC	56.683	Loss
CAMK_CAMKL_AMPK_PRKAA1_ST	P41235	HNF4A	Q13131	PRKAA1	T139	E133D	133	Missense	distal	-6	no	54.374	58.141	EPSD	ICGC	56.683	Gain
CAMK_CAMKL_AMPK_PRKAA1_ST	P41235	HNF4A	Q13131	PRKAA1	S143	T139I	139	Missense	distal	-4	no	62.819	61.276	EPSD	ICGC;COSMIC	56.683	Down-regulation
CAMK_CAMKL_AMPK_PRKAA1_ST	P41235	HNF4A	Q13131	PRKAA1	S143	S148C	148	Missense	distal	5	no	62.819	62.855	EPSD	ICGC;COSMIC	56.683	Up-regulation
CAMK_CAMKL_AMPK_PRKAA1_ST	P41235	HNF4A	Q13131	PRKAA1	S143	S148I	148	Missense	distal	5	no	62.819	62.782	EPSD	ICGC	56.683	Down-regulation
CAMK_CAMKL_AMPK_PRKAA1_ST	P41235	HNF4A	Q13131	PRKAA1	S151	I152F	152	Missense	proximal	1	no	50.914	57.033	EPSD	ICGC;COSMIC	56.683	Gain
CAMK_CAMKL_AMPK_PRKAA1_ST	P41235	HNF4A	Q13131	PRKAA1	T166	V169I	169	Missense	distal	3	no	65.932	62.658	EPSD	ICGC;GDSC	56.683	Down-regulation
CAMK_CAMKL_AMPK_PRKAA1_ST	P41235	HNF4A	Q13131	PRKAA1	S170	G174C	174	Missense	distal	4	no	56.727	38.075	EPSD	ICGC	56.683	Loss
CAMK_CAMKL_AMPK_PRKAA1_ST	P41235	HNF4A	Q13131	PRKAA1	S170	R177W	177	Missense	distal	7	no	56.727	56.952	EPSD	ICGC;COSMIC	56.683	Up-regulation
CAMK_CAMKL_AMPK_PRKAA1_ST	P41235	HNF4A	Q13131	PRKAA1	S170	V169I	169	Missense	proximal	-1	no	56.727	56.811	EPSD	ICGC;GDSC	56.683	Up-regulation
CAMK_CAMKL_AMPK_PRKAA1_ST	P41235	HNF4A	Q13131	PRKAA1	S303	A299S	299	Missense	distal	-4	no	58.110	58.510	EPSD	ICGC	56.683	Up-regulation
CAMK_CAMKL_AMPK_PRKAA1_ST	P49674	CSNK1E	Q13131	PRKAA1	T250	R256C	256	Missense	distal	6	no	60.708	61.039	EPSD	ICGC;COSMIC	56.683	Up-regulation
CAMK_CAMKL_AMPK_PRKAA1_ST	P49674	CSNK1E	Q13131	PRKAA1	T250	S257F	257	Missense	distal	7	no	60.708	59.441	EPSD	ICGC	56.683	Down-regulation
CAMK_CAMKL_AMPK_PRKAA1_ST	P49674	CSNK1E	Q13131	PRKAA1	T250	P245T	245	Missense	distal	-5	no	60.708	59.785	EPSD	ICGC	56.683	Down-regulation
CAMK_CAMKL_AMPK_PRKAA1_ST	P49674	CSNK1E	Q13131	PRKAA1	T250	R256S	256	Missense	distal	6	no	60.708	60.815	EPSD	ICGC;COSMIC	56.683	Up-regulation
CAMK_CAMKL_AMPK_PRKAA1_ST	P49674	CSNK1E	Q13131	PRKAA1	T250	G243D	243	Missense	distal	-7	no	60.708	59.404	EPSD	ICGC;COSMIC	56.683	Down-regulation
CAMK_CAMKL_AMPK_PRKAA1_ST	P49674	CSNK1E	Q13131	PRKAA1	S368	R369W	369	Missense	proximal	1	no	60.311	60.916	EPSD	ICGC;COSMIC	56.683	Up-regulation
CAMK_CAMKL_AMPK_PRKAA1_ST	P49674	CSNK1E	Q13131	PRKAA1	S389	R396L	396	Missense	distal	7	no	66.528	67.156	PhosphoSitePlus	ICGC;COSMIC	56.683	Up-regulation
CAMK_CAMKL_AMPK_PRKAA1_ST	P49674	CSNK1E	Q13131	PRKAA1	S390	R396L	396	Missense	distal	6	no	63.455	63.696	EPSD	ICGC;COSMIC	56.683	Up-regulation
CAMK_CAMKL_AMPK_PRKAA1_ST	P49674	CSNK1E	Q13131	PRKAA1	T407	Q406K	406	Missense	proximal	-1	no	57.400	57.299	EPSD	ICGC	56.683	Down-regulation
CAMK_CAMKL_AMPK_PRKAA1_ST	P04626	ERBB2	Q13131	PRKAA1	T701	E695D	695	Missense	distal	-6	no	53.987	57.753	EPSD	ICGC	56.683	Gain
CAMK_CAMKL_AMPK_PRKAA1_ST	P04626	ERBB2	Q13131	PRKAA1	S760	A763T	763	Missense	distal	3	no	58.153	61.068	EPSD	ICGC;COSMIC	56.683	Up-regulation
CAMK_CAMKL_AMPK_PRKAA1_ST	Q14694	USP10	Q13131	PRKAA1	S76	D69H	69	Missense	distal	-7	no	64.269	61.134	PhosphoSitePlus	ICGC;COSMIC	56.683	Down-regulation
CAMK_CAMKL_AMPK_PRKAA1_ST	Q14694	USP10	Q13131	PRKAA1	S331	T327M	327	Missense	distal	-4	no	57.713	57.501	EPSD	ICGC;COSMIC	56.683	Down-regulation
CAMK_CAMKL_AMPK_PRKAA1_ST	Q14694	USP10	Q13131	PRKAA1	S331	A324P	324	Missense	distal	-7	no	57.713	58.148	EPSD	ICGC;COSMIC	56.683	Up-regulation
CAMK_CAMKL_AMPK_PRKAA1_ST	Q14694	USP10	Q13131	PRKAA1	S354	S353Y	353	Missense	proximal	-1	no	56.944	57.058	EPSD	ICGC;COSMIC	56.683	Up-regulation
CAMK_CAMKL_AMPK_PRKAA1_ST	P22460	KCNA5	Q13131	PRKAA1	S559	G558E	558	Missense	proximal	-1	no	57.162	57.076	PhosphoSitePlus	ICGC	56.683	Down-regulation
CAMK_CAMKL_AMPK_PRKAA1_ST	Q9NRC8	SIRT7	Q13131	PRKAA1	S94	A93D	93	Missense	proximal	-1	no	56.718	56.697	EPSD	ICGC	56.683	Down-regulation
CAMK_CAMKL_AMPK_PRKAA1_ST	Q9NRC8	SIRT7	Q13131	PRKAA1	S94	N98K	98	Missense	distal	4	no	56.718	59.291	EPSD	ICGC	56.683	Up-regulation
CAMK_CAMKL_AMPK_PRKAA1_ST	O15360	FANCA	Q13131	PRKAA1	S73	K71Q	71	Missense	proximal	-2	no	60.311	59.396	EPSD	ICGC;COSMIC	56.683	Down-regulation
CAMK_CAMKL_AMPK_PRKAA1_ST	O15360	FANCA	Q13131	PRKAA1	S347	T351K	351	Missense	distal	4	no	62.410	64.023	PhosphoSitePlus	ICGC	56.683	Up-regulation
CAMK_CAMKL_AMPK_PRKAA1_ST	O15360	FANCA	Q13131	PRKAA1	S1301	A1304T	1304	Missense	distal	3	no	56.946	59.861	EPSD	ICGC;COSMIC	56.683	Up-regulation
CAMK_CAMKL_AMPK_PRKAA1_ST	O15360	FANCA	Q13131	PRKAA1	S1301	A1304E	1304	Missense	distal	3	no	56.946	59.957	EPSD	ICGC	56.683	Up-regulation
CAMK_CAMKL_AMPK_PRKAA1_ST	O15360	FANCA	Q13131	PRKAA1	T1309	A1304E	1304	Missense	distal	-5	no	55.210	57.263	EPSD	ICGC	56.683	Gain
CAMK_CAMKL_AMPK_PRKAA1_ST	O95239	KIF4A	Q13131	PRKAA1	S407	G405V	405	Missense	proximal	-2	no	56.135	59.448	EPSD	ICGC;COSMIC	56.683	Gain
CAMK_CAMKL_AMPK_PRKAA1_ST	O95239	KIF4A	Q13131	PRKAA1	T544	L539Q	539	Missense	distal	-5	no	65.878	59.019	EPSD	ICGC;COSMIC	56.683	Down-regulation
CAMK_CAMKL_AMPK_PRKAA1_ST	O95239	KIF4A	Q13131	PRKAA1	S634	R641W	641	Missense	distal	7	no	58.391	58.616	EPSD	ICGC;COSMIC	56.683	Up-regulation
CAMK_CAMKL_AMPK_PRKAA1_ST	O95239	KIF4A	Q13131	PRKAA1	S634	R641L	641	Missense	distal	7	no	58.391	59.018	EPSD	ICGC;COSMIC	56.683	Up-regulation
CAMK_CAMKL_AMPK_PRKAA1_ST	O95239	KIF4A	Q13131	PRKAA1	S787	E786K	786	Missense	proximal	-1	no	57.804	57.779	EPSD	ICGC	56.683	Down-regulation
CAMK_CAMKL_AMPK_PRKAA1_ST	O95239	KIF4A	Q13131	PRKAA1	T799	R796L	796	Missense	distal	-3	no	56.949	46.982	EPSD	ICGC	56.683	Loss
CAMK_CAMKL_AMPK_PRKAA1_ST	O95239	KIF4A	Q13131	PRKAA1	S801	R796L	796	Missense	distal	-5	no	69.354	70.531	PhosphoSitePlus	ICGC	56.683	Up-regulation
CAMK_CAMKL_AMPK_PRKAA1_ST	O95239	KIF4A	Q13131	PRKAA1	S1017	V1021A	1021	Missense	distal	4	no	61.038	61.005	EPSD	ICGC	56.683	Down-regulation
CAMK_CAMKL_AMPK_PRKAA1_ST	O95239	KIF4A	Q13131	PRKAA1	S1017	P1022Q	1022	Missense	distal	5	no	61.038	61.080	EPSD	ICGC;COSMIC	56.683	Up-regulation
CAMK_CAMKL_AMPK_PRKAA1_ST	O95239	KIF4A	Q13131	PRKAA1	S1048	H1055Y	1055	Missense	distal	7	no	58.577	60.138	EPSD	ICGC;COSMIC	56.683	Up-regulation
CAMK_CAMKL_AMPK_PRKAA1_ST	O95239	KIF4A	Q13131	PRKAA1	S1186	P1185H	1185	Missense	proximal	-1	no	58.170	58.202	EPSD	ICGC;COSMIC	56.683	Up-regulation
CAMK_CAMKL_AMPK_PRKAA1_ST	O75385	ULK1	Q13131	PRKAA1	S111	R108H	108	Missense	distal	-3	no	57.033	49.176	EPSD	ICGC;CCLE	56.683	Loss
CAMK_CAMKL_AMPK_PRKAA1_ST	O75385	ULK1	Q13131	PRKAA1	S111	A106T	106	Missense	distal	-5	no	57.033	55.040	EPSD	ICGC	56.683	Loss
CAMK_CAMKL_AMPK_PRKAA1_ST	O75385	ULK1	Q13131	PRKAA1	S111	R108C	108	Missense	distal	-3	no	57.033	42.885	EPSD	ICGC	56.683	Loss
CAMK_CAMKL_AMPK_PRKAA1_ST	O75385	ULK1	Q13131	PRKAA1	S294	S298L	298	Missense	distal	4	no	53.395	59.983	EPSD	ICGC;COSMIC;GDSC;CCLE	56.683	Gain
CAMK_CAMKL_AMPK_PRKAA1_ST	O75385	ULK1	Q13131	PRKAA1	S304	S298L	298	Missense	distal	-6	no	62.291	62.601	EPSD	ICGC;COSMIC;GDSC;CCLE	56.683	Up-regulation
CAMK_CAMKL_AMPK_PRKAA1_ST	O75385	ULK1	Q13131	PRKAA1	S304	G301V	301	Missense	distal	-3	no	62.291	62.911	EPSD	ICGC	56.683	Up-regulation
CAMK_CAMKL_AMPK_PRKAA1_ST	O75385	ULK1	Q13131	PRKAA1	S317	P315T	315	Missense	proximal	-2	no	64.086	60.854	EPSD	ICGC;COSMIC	56.683	Down-regulation
CAMK_CAMKL_AMPK_PRKAA1_ST	O75385	ULK1	Q13131	PRKAA1	S403	G399C	399	Missense	distal	-4	no	49.780	57.698	EPSD	ICGC;COSMIC	56.683	Gain
CAMK_CAMKL_AMPK_PRKAA1_ST	O75385	ULK1	Q13131	PRKAA1	S424	S422Y	422	Missense	proximal	-2	no	57.223	55.661	EPSD	ICGC;COSMIC	56.683	Loss
CAMK_CAMKL_AMPK_PRKAA1_ST	O75385	ULK1	Q13131	PRKAA1	S495	P501H	501	Missense	distal	6	no	66.399	66.413	EPSD	ICGC;COSMIC	56.683	Up-regulation
CAMK_CAMKL_AMPK_PRKAA1_ST	O75385	ULK1	Q13131	PRKAA1	S538	R535C	535	Missense	distal	-3	no	59.648	45.501	EPSD	ICGC	56.683	Loss
CAMK_CAMKL_AMPK_PRKAA1_ST	O75385	ULK1	Q13131	PRKAA1	S556	R553H	553	Missense	distal	-3	no	75.749	67.893	EPSD	ICGC;COSMIC	56.683	Down-regulation
CAMK_CAMKL_AMPK_PRKAA1_ST	O75385	ULK1	Q13131	PRKAA1	S556	A557T	557	Missense	proximal	1	no	75.749	76.302	EPSD	ICGC;COSMIC	56.683	Up-regulation
CAMK_CAMKL_AMPK_PRKAA1_ST	O75385	ULK1	Q13131	PRKAA1	S556	G551V	551	Missense	distal	-5	no	75.749	75.071	EPSD	ICGC	56.683	Down-regulation
CAMK_CAMKL_AMPK_PRKAA1_ST	O75385	ULK1	Q13131	PRKAA1	T660	R657L	657	Missense	distal	-3	no	65.978	56.012	EPSD	ICGC	56.683	Loss
CAMK_CAMKL_AMPK_PRKAA1_ST	O75385	ULK1	Q13131	PRKAA1	T660	D663Y	663	Missense	distal	3	no	65.978	66.158	EPSD	ICGC	56.683	Up-regulation
CAMK_CAMKL_AMPK_PRKAA1_ST	O75385	ULK1	Q13131	PRKAA1	S694	D700N	700	Missense	distal	6	no	59.634	59.817	EPSD	ICGC;COSMIC	56.683	Up-regulation
CAMK_CAMKL_AMPK_PRKAA1_ST	O75385	ULK1	Q13131	PRKAA1	S694	S694I	694	Missense	central	0	yes	59.634	0.000	EPSD	ICGC	56.683	Loss
CAMK_CAMKL_AMPK_PRKAA1_ST	O75385	ULK1	Q13131	PRKAA1	S694	R691L	691	Missense	distal	-3	no	59.634	49.668	EPSD	ICGC	56.683	Loss
CAMK_CAMKL_AMPK_PRKAA1_ST	O75385	ULK1	Q13131	PRKAA1	S694	D700Y	700	Missense	distal	6	no	59.634	60.021	EPSD	ICGC;COSMIC	56.683	Up-regulation
CAMK_CAMKL_AMPK_PRKAA1_ST	O75385	ULK1	Q13131	PRKAA1	S694	G687V	687	Missense	distal	-7	no	59.634	57.836	EPSD	ICGC	56.683	Down-regulation
CAMK_CAMKL_AMPK_PRKAA1_ST	O75385	ULK1	Q13131	PRKAA1	T755	P759L	759	Missense	distal	4	no	51.728	58.468	EPSD	ICGC	56.683	Gain
CAMK_CAMKL_AMPK_PRKAA1_ST	O75385	ULK1	Q13131	PRKAA1	S775	T771S	771	Missense	distal	-4	no	57.899	59.155	EPSD	ICGC;COSMIC	56.683	Up-regulation
CAMK_CAMKL_AMPK_PRKAA1_ST	O15350	TP73	Q13131	PRKAA1	T27	S20I	20	Missense	distal	-7	no	69.200	66.848	EPSD	ICGC	56.683	Down-regulation
CAMK_CAMKL_AMPK_PRKAA1_ST	O15350	TP73	Q13131	PRKAA1	T27	D30Y	30	Missense	distal	3	no	69.200	69.379	EPSD	ICGC	56.683	Up-regulation
CAMK_CAMKL_AMPK_PRKAA1_ST	O15350	TP73	Q13131	PRKAA1	S47	G44R	44	Missense	distal	-3	no	48.765	57.800	EPSD	ICGC;COSMIC;GDSC;CCLE	56.683	Gain
CAMK_CAMKL_AMPK_PRKAA1_ST	O15350	TP73	Q13131	PRKAA1	S223	V217M	217	Missense	distal	-6	no	58.421	58.763	EPSD	ICGC;COSMIC	56.683	Up-regulation
CAMK_CAMKL_AMPK_PRKAA1_ST	O15350	TP73	Q13131	PRKAA1	S223	V230A	230	Missense	distal	7	no	58.421	60.839	EPSD	ICGC;COSMIC	56.683	Up-regulation
CAMK_CAMKL_AMPK_PRKAA1_ST	O15350	TP73	Q13131	PRKAA1	S235	V230A	230	Missense	distal	-5	no	56.156	57.349	EPSD	ICGC;COSMIC	56.683	Gain
CAMK_CAMKL_AMPK_PRKAA1_ST	O15350	TP73	Q13131	PRKAA1	S235	P242L	242	Missense	distal	7	no	56.156	56.696	EPSD	ICGC;COSMIC	56.683	Gain
CAMK_CAMKL_AMPK_PRKAA1_ST	O15350	TP73	Q13131	PRKAA1	S426	M421I	421	Missense	distal	-5	no	65.075	65.821	PhosphoSitePlus	ICGC;COSMIC	56.683	Up-regulation
CAMK_CAMKL_AMPK_PRKAA1_ST	O15350	TP73	Q13131	PRKAA1	S426	G432V	432	Missense	distal	6	no	65.075	65.192	PhosphoSitePlus	ICGC	56.683	Up-regulation
CAMK_CAMKL_AMPK_PRKAA1_ST	O15350	TP73	Q13131	PRKAA1	S426	G432D	432	Missense	distal	6	no	65.075	65.003	PhosphoSitePlus	ICGC;COSMIC;GDSC;CCLE	56.683	Down-regulation
CAMK_CAMKL_AMPK_PRKAA1_ST	O15350	TP73	Q13131	PRKAA1	S471	S471R	471	Missense	central	0	yes	61.982	0.000	EPSD	ICGC;COSMIC	56.683	Loss
CAMK_CAMKL_AMPK_PRKAA1_ST	O15350	TP73	Q13131	PRKAA1	S471	S474F	474	Missense	distal	3	no	61.982	60.774	EPSD	ICGC	56.683	Down-regulation
CAMK_CAMKL_AMPK_PRKAA1_ST	Q05469	LIPE	Q13131	PRKAA1	S200	A194S	194	Missense	distal	-6	no	63.427	62.757	EPSD	ICGC;COSMIC	56.683	Down-regulation
CAMK_CAMKL_AMPK_PRKAA1_ST	Q05469	LIPE	Q13131	PRKAA1	S200	G205V	205	Missense	distal	5	no	63.427	63.417	EPSD	ICGC	56.683	Down-regulation
CAMK_CAMKL_AMPK_PRKAA1_ST	Q05469	LIPE	Q13131	PRKAA1	T202	G205V	205	Missense	distal	3	no	56.926	56.620	EPSD	ICGC	56.683	Loss
CAMK_CAMKL_AMPK_PRKAA1_ST	Q05469	LIPE	Q13131	PRKAA1	S607	R611C	611	Missense	distal	4	no	63.227	42.374	EPSD	ICGC	56.683	Loss
CAMK_CAMKL_AMPK_PRKAA1_ST	Q05469	LIPE	Q13131	PRKAA1	S607	P600H	600	Missense	distal	-7	no	63.227	61.475	EPSD	ICGC;COSMIC	56.683	Down-regulation
CAMK_CAMKL_AMPK_PRKAA1_ST	Q05469	LIPE	Q13131	PRKAA1	S621	S625F	625	Missense	distal	4	no	56.754	59.147	EPSD	ICGC;COSMIC	56.683	Up-regulation
CAMK_CAMKL_AMPK_PRKAA1_ST	Q05469	LIPE	Q13131	PRKAA1	S621	G627D	627	Missense	distal	6	no	56.754	56.682	EPSD	ICGC;COSMIC	56.683	Loss
CAMK_CAMKL_AMPK_PRKAA1_ST	Q05469	LIPE	Q13131	PRKAA1	T813	R810W	810	Missense	distal	-3	no	63.032	-29.968	EPSD	ICGC;COSMIC	56.683	Loss
CAMK_CAMKL_AMPK_PRKAA1_ST	Q05469	LIPE	Q13131	PRKAA1	T813	V809L	809	Missense	distal	-4	no	63.032	62.929	EPSD	ICGC;COSMIC	56.683	Down-regulation
CAMK_CAMKL_AMPK_PRKAA1_ST	Q05469	LIPE	Q13131	PRKAA1	S855	R852H	852	Missense	distal	-3	no	68.178	60.322	PhosphoSitePlus	ICGC;COSMIC	56.683	Down-regulation
CAMK_CAMKL_AMPK_PRKAA1_ST	Q05469	LIPE	Q13131	PRKAA1	S904	P903T	903	Missense	proximal	-1	no	57.314	57.302	EPSD	ICGC	56.683	Down-regulation
CAMK_CAMKL_AMPK_PRKAA1_ST	Q05469	LIPE	Q13131	PRKAA1	S904	F911L	911	Missense	distal	7	no	57.314	58.623	EPSD	ICGC	56.683	Up-regulation
CAMK_CAMKL_AMPK_PRKAA1_ST	Q05469	LIPE	Q13131	PRKAA1	S904	S904F	904	Missense	central	0	yes	57.314	0.000	EPSD	ICGC	56.683	Loss
CAMK_CAMKL_AMPK_PRKAA1_ST	Q6N021	TET2	Q13131	PRKAA1	T32	P29R	29	Missense	distal	-3	no	54.634	63.494	EPSD	ICGC;COSMIC	56.683	Gain
CAMK_CAMKL_AMPK_PRKAA1_ST	Q6N021	TET2	Q13131	PRKAA1	S99	G93E	93	Missense	distal	-6	no	59.609	58.722	PhosphoSitePlus	ICGC;COSMIC	56.683	Down-regulation
CAMK_CAMKL_AMPK_PRKAA1_ST	Q6N021	TET2	Q13131	PRKAA1	S99	P101H	101	Missense	proximal	2	no	59.609	59.455	PhosphoSitePlus	ICGC;COSMIC	56.683	Down-regulation
CAMK_CAMKL_AMPK_PRKAA1_ST	Q6N021	TET2	Q13131	PRKAA1	S99	I94M	94	Missense	distal	-5	no	59.609	58.863	PhosphoSitePlus	ICGC;COSMIC	56.683	Down-regulation
CAMK_CAMKL_AMPK_PRKAA1_ST	Q6N021	TET2	Q13131	PRKAA1	S315	A309E	309	Missense	distal	-6	no	58.201	56.151	EPSD	ICGC;COSMIC	56.683	Loss
CAMK_CAMKL_AMPK_PRKAA1_ST	Q6N021	TET2	Q13131	PRKAA1	S327	S334F	334	Missense	distal	7	no	57.664	56.396	EPSD	ICGC;COSMIC	56.683	Loss
CAMK_CAMKL_AMPK_PRKAA1_ST	Q6N021	TET2	Q13131	PRKAA1	T467	S462I	462	Missense	distal	-5	no	54.197	58.958	EPSD	ICGC	56.683	Gain
CAMK_CAMKL_AMPK_PRKAA1_ST	Q6N021	TET2	Q13131	PRKAA1	T495	P499L	499	Missense	distal	4	no	51.372	58.112	EPSD	ICGC;COSMIC	56.683	Gain
CAMK_CAMKL_AMPK_PRKAA1_ST	Q6N021	TET2	Q13131	PRKAA1	S585	S588T	588	Missense	distal	3	no	62.930	61.866	EPSD	ICGC	56.683	Down-regulation
CAMK_CAMKL_AMPK_PRKAA1_ST	Q6N021	TET2	Q13131	PRKAA1	S585	R581C	581	Missense	distal	-4	no	62.930	67.241	EPSD	ICGC;COSMIC	56.683	Up-regulation
CAMK_CAMKL_AMPK_PRKAA1_ST	Q6N021	TET2	Q13131	PRKAA1	S817	R814C	814	Missense	distal	-3	no	60.010	45.863	EPSD	ICGC;COSMIC;GDSC;CCLE	56.683	Loss
CAMK_CAMKL_AMPK_PRKAA1_ST	Q6N021	TET2	Q13131	PRKAA1	S817	P818T	818	Missense	proximal	1	no	60.010	59.600	EPSD	ICGC;COSMIC	56.683	Down-regulation
CAMK_CAMKL_AMPK_PRKAA1_ST	Q6N021	TET2	Q13131	PRKAA1	S1076	P1079T	1079	Missense	distal	3	no	60.091	61.265	EPSD	ICGC;COSMIC	56.683	Up-regulation
CAMK_CAMKL_AMPK_PRKAA1_ST	Q6N021	TET2	Q13131	PRKAA1	T1331	S1324Y	1324	Missense	distal	-7	no	60.237	58.098	EPSD	ICGC;COSMIC	56.683	Down-regulation
CAMK_CAMKL_AMPK_PRKAA1_ST	Q6N021	TET2	Q13131	PRKAA1	S1449	M1456I	1456	Missense	distal	7	no	64.294	65.164	EPSD	ICGC	56.683	Up-regulation
CAMK_CAMKL_AMPK_PRKAA1_ST	Q6N021	TET2	Q13131	PRKAA1	S1449	A1443G	1443	Missense	distal	-6	no	64.294	63.131	EPSD	ICGC	56.683	Down-regulation
CAMK_CAMKL_AMPK_PRKAA1_ST	Q6N021	TET2	Q13131	PRKAA1	S1970	K1969N	1969	Missense	proximal	-1	no	60.402	60.469	EPSD	ICGC	56.683	Up-regulation
CAMK_CAMKL_AMPK_PRKAA1_ST	Q6N021	TET2	Q13131	PRKAA1	S1970	A1972S	1972	Missense	proximal	2	no	60.402	60.603	EPSD	ICGC	56.683	Up-regulation
CAMK_CAMKL_AMPK_PRKAA1_ST	Q15910	EZH2	Q13131	PRKAA1	T718	E721D	721	Missense	distal	3	no	55.943	57.652	EPSD	ICGC;COSMIC	56.683	Gain
CAMK_CAMKL_AMPK_PRKAA1_ST	P36956	SREBF1	Q13131	PRKAA1	S1019	Q1026H	1026	Missense	distal	7	no	60.775	58.684	EPSD	ICGC;COSMIC	56.683	Down-regulation
CAMK_CAMKL_AMPK_PRKAA1_ST	Q09472	EP300	Q13131	PRKAA1	S89	L93F	93	Missense	distal	4	no	74.231	70.036	PhosphoSitePlus	ICGC	56.683	Down-regulation
CAMK_CAMKL_AMPK_PRKAA1_ST	Q09472	EP300	Q13131	PRKAA1	T845	R838C	838	Missense	distal	-7	no	62.942	61.550	EPSD	ICGC;COSMIC	56.683	Down-regulation
CAMK_CAMKL_AMPK_PRKAA1_ST	Q09472	EP300	Q13131	PRKAA1	T857	Q853R	853	Missense	distal	-4	no	57.328	58.796	EPSD	ICGC	56.683	Up-regulation
CAMK_CAMKL_AMPK_PRKAA1_ST	Q09472	EP300	Q13131	PRKAA1	T1190	R1187H	1187	Missense	distal	-3	no	62.566	54.710	EPSD	ICGC;COSMIC	56.683	Loss
CAMK_CAMKL_AMPK_PRKAA1_ST	Q09472	EP300	Q13131	PRKAA1	S1534	D1539Y	1539	Missense	distal	5	no	58.344	58.325	EPSD	ICGC	56.683	Down-regulation
CAMK_CAMKL_AMPK_PRKAA1_ST	Q09472	EP300	Q13131	PRKAA1	S1534	R1527G	1527	Missense	distal	-7	no	58.344	59.759	EPSD	ICGC;COSMIC	56.683	Up-regulation
CAMK_CAMKL_AMPK_PRKAA1_ST	Q09472	EP300	Q13131	PRKAA1	S1534	T1533N	1533	Missense	proximal	-1	no	58.344	58.361	EPSD	ICGC	56.683	Up-regulation
CAMK_CAMKL_AMPK_PRKAA1_ST	Q09472	EP300	Q13131	PRKAA1	S1834	R1829H	1829	Missense	distal	-5	no	58.929	53.548	EPSD	ICGC;COSMIC	56.683	Loss
CAMK_CAMKL_AMPK_PRKAA1_ST	Q09472	EP300	Q13131	PRKAA1	S1834	A1833T	1833	Missense	proximal	-1	no	58.929	58.850	EPSD	ICGC;COSMIC	56.683	Down-regulation
CAMK_CAMKL_AMPK_PRKAA1_ST	Q09472	EP300	Q13131	PRKAA1	S1834	R1829L	1829	Missense	distal	-5	no	58.929	60.106	EPSD	ICGC	56.683	Up-regulation
CAMK_CAMKL_AMPK_PRKAA1_ST	Q09472	EP300	Q13131	PRKAA1	S1834	R1831S	1831	Missense	distal	-3	no	58.929	49.534	EPSD	ICGC	56.683	Loss
CAMK_CAMKL_AMPK_PRKAA1_ST	Q09472	EP300	Q13131	PRKAA1	S1849	P1850S	1850	Missense	proximal	1	no	59.898	60.530	EPSD	ICGC;COSMIC	56.683	Up-regulation
CAMK_CAMKL_AMPK_PRKAA1_ST	Q86TI0	TBC1D1	Q13131	PRKAA1	S237	R233C	233	Missense	distal	-4	no	63.626	67.937	EPSD;PhosphoSitePlus	ICGC	56.683	Up-regulation
CAMK_CAMKL_AMPK_PRKAA1_ST	Q86TI0	TBC1D1	Q13131	PRKAA1	S237	P231S	231	Missense	distal	-6	no	63.626	63.276	EPSD;PhosphoSitePlus	ICGC	56.683	Down-regulation
CAMK_CAMKL_AMPK_PRKAA1_ST	Q86TI0	TBC1D1	Q13131	PRKAA1	S237	S237P	237	Missense	central	0	yes	63.626	0.000	EPSD;PhosphoSitePlus	ICGC;COSMIC	56.683	Loss
CAMK_CAMKL_AMPK_PRKAA1_ST	Q86TI0	TBC1D1	Q13131	PRKAA1	S407	K409E	409	Missense	proximal	2	no	57.512	57.905	EPSD	ICGC	56.683	Up-regulation
CAMK_CAMKL_AMPK_PRKAA1_ST	Q86TI0	TBC1D1	Q13131	PRKAA1	S407	M405T	405	Missense	proximal	-2	no	57.512	57.242	EPSD	ICGC;COSMIC	56.683	Down-regulation
CAMK_CAMKL_AMPK_PRKAA1_ST	Q86TI0	TBC1D1	Q13131	PRKAA1	S513	S513F	513	Missense	central	0	yes	57.727	0.000	EPSD	ICGC	56.683	Loss
CAMK_CAMKL_AMPK_PRKAA1_ST	Q86TI0	TBC1D1	Q13131	PRKAA1	S513	G515C	515	Missense	proximal	2	no	57.727	56.940	EPSD	ICGC	56.683	Down-regulation
CAMK_CAMKL_AMPK_PRKAA1_ST	Q86TI0	TBC1D1	Q13131	PRKAA1	S513	K517N	517	Missense	distal	4	no	57.727	55.155	EPSD	ICGC	56.683	Loss
CAMK_CAMKL_AMPK_PRKAA1_ST	Q86TI0	TBC1D1	Q13131	PRKAA1	T596	R593Q	593	Missense	distal	-3	no	59.857	51.913	PhosphoSitePlus;EPSD	ICGC;COSMIC	56.683	Loss
CAMK_CAMKL_AMPK_PRKAA1_ST	Q86TI0	TBC1D1	Q13131	PRKAA1	S598	R593Q	593	Missense	distal	-5	no	60.694	55.012	EPSD	ICGC;COSMIC	56.683	Loss
CAMK_CAMKL_AMPK_PRKAA1_ST	Q86TI0	TBC1D1	Q13131	PRKAA1	T716	P709S	709	Missense	distal	-7	no	54.897	57.164	EPSD	ICGC;COSMIC	56.683	Gain
CAMK_CAMKL_AMPK_PRKAA1_ST	Q9H3M7	TXNIP	Q13131	PRKAA1	S304	S311N	311	Missense	distal	7	no	62.361	62.662	EPSD	ICGC	56.683	Up-regulation
CAMK_CAMKL_AMPK_PRKAA1_ST	Q9H3M7	TXNIP	Q13131	PRKAA1	S304	G297C	297	Missense	distal	-7	no	62.361	59.553	EPSD	ICGC;COSMIC	56.683	Down-regulation
CAMK_CAMKL_AMPK_PRKAA1_ST	Q9H3M7	TXNIP	Q13131	PRKAA1	S304	R305S	305	Missense	proximal	1	no	62.361	63.348	EPSD	ICGC;COSMIC	56.683	Up-regulation
CAMK_CAMKL_AMPK_PRKAA1_ST	Q9H3M7	TXNIP	Q13131	PRKAA1	S308	S311N	311	Missense	distal	3	no	62.136	64.130	PhosphoSitePlus	ICGC	56.683	Up-regulation
CAMK_CAMKL_AMPK_PRKAA1_ST	Q9H3M7	TXNIP	Q13131	PRKAA1	S308	R305S	305	Missense	distal	-3	no	62.136	52.741	PhosphoSitePlus	ICGC;COSMIC	56.683	Loss
CAMK_CAMKL_AMPK_PRKAA1_ST	Q9H3M7	TXNIP	Q13131	PRKAA1	S315	S311N	311	Missense	distal	-4	no	61.575	56.776	EPSD	ICGC	56.683	Down-regulation
CAMK_CAMKL_AMPK_PRKAA1_ST	Q9H3M7	TXNIP	Q13131	PRKAA1	S318	S311N	311	Missense	distal	-7	no	61.125	60.034	EPSD	ICGC	56.683	Down-regulation
CAMK_CAMKL_AMPK_PRKAA1_ST	Q9H3M7	TXNIP	Q13131	PRKAA1	S318	P325T	325	Missense	distal	7	no	61.125	61.377	EPSD	ICGC;COSMIC	56.683	Up-regulation
CAMK_CAMKL_AMPK_PRKAA1_ST	Q9H3M7	TXNIP	Q13131	PRKAA1	S361	D354Y	354	Missense	distal	-7	no	58.179	56.925	EPSD	ICGC	56.683	Down-regulation
CAMK_CAMKL_AMPK_PRKAA1_ST	Q9H3M7	TXNIP	Q13131	PRKAA1	S361	D354N	354	Missense	distal	-7	no	58.179	57.973	EPSD	ICGC;COSMIC	56.683	Down-regulation
CAMK_CAMKL_AMPK_PRKAA1_ST	Q07866	KLC1	Q13131	PRKAA1	S460	V463A	463	Missense	distal	3	no	66.109	61.233	EPSD	ICGC;COSMIC	56.683	Down-regulation
CAMK_CAMKL_AMPK_PRKAA1_ST	Q07866	KLC1	Q13131	PRKAA1	S521	S524R	524	Missense	distal	3	no	59.065	58.415	PhosphoSitePlus	ICGC	56.683	Down-regulation
CAMK_CAMKL_AMPK_PRKAA1_ST	Q07866	KLC1	Q13131	PRKAA1	S521	D528G	528	Missense	distal	7	no	59.065	60.234	PhosphoSitePlus	ICGC	56.683	Up-regulation
CAMK_CAMKL_AMPK_PRKAA1_ST	Q07866	KLC1	Q13131	PRKAA1	S524	V530F	530	Missense	distal	6	no	60.598	60.974	EPSD	ICGC;COSMIC	56.683	Up-regulation
CAMK_CAMKL_AMPK_PRKAA1_ST	Q07866	KLC1	Q13131	PRKAA1	S524	S524R	524	Missense	central	0	yes	60.598	0.000	EPSD	ICGC	56.683	Loss
CAMK_CAMKL_AMPK_PRKAA1_ST	Q07866	KLC1	Q13131	PRKAA1	S524	D528G	528	Missense	distal	4	no	60.598	60.240	EPSD	ICGC	56.683	Down-regulation
CAMK_CAMKL_AMPK_PRKAA1_ST	P26358	DNMT1	Q13131	PRKAA1	S91	H97R	97	Missense	distal	6	no	58.809	58.704	EPSD	ICGC;COSMIC	56.683	Down-regulation
CAMK_CAMKL_AMPK_PRKAA1_ST	P26358	DNMT1	Q13131	PRKAA1	S91	N87S	87	Missense	distal	-4	no	58.809	63.609	EPSD	ICGC	56.683	Up-regulation
CAMK_CAMKL_AMPK_PRKAA1_ST	P26358	DNMT1	Q13131	PRKAA1	S91	L85I	85	Missense	distal	-6	no	58.809	55.825	EPSD	ICGC	56.683	Loss
CAMK_CAMKL_AMPK_PRKAA1_ST	P26358	DNMT1	Q13131	PRKAA1	T137	P138L	138	Missense	proximal	1	no	61.124	60.831	EPSD	ICGC;COSMIC	56.683	Down-regulation
CAMK_CAMKL_AMPK_PRKAA1_ST	P26358	DNMT1	Q13131	PRKAA1	T137	P135T	135	Missense	proximal	-2	no	61.124	57.893	EPSD	ICGC	56.683	Down-regulation
CAMK_CAMKL_AMPK_PRKAA1_ST	P26358	DNMT1	Q13131	PRKAA1	T137	R139K	139	Missense	proximal	2	no	61.124	61.240	EPSD	ICGC;COSMIC	56.683	Up-regulation
CAMK_CAMKL_AMPK_PRKAA1_ST	P26358	DNMT1	Q13131	PRKAA1	T137	R139S	139	Missense	proximal	2	no	61.124	61.030	EPSD	ICGC;COSMIC	56.683	Down-regulation
CAMK_CAMKL_AMPK_PRKAA1_ST	P26358	DNMT1	Q13131	PRKAA1	T137	R136H	136	Missense	proximal	-1	no	61.124	61.144	EPSD	ICGC;COSMIC	56.683	Up-regulation
CAMK_CAMKL_AMPK_PRKAA1_ST	P26358	DNMT1	Q13131	PRKAA1	S143	P138L	138	Missense	distal	-5	no	65.756	70.496	EPSD	ICGC;COSMIC	56.683	Up-regulation
CAMK_CAMKL_AMPK_PRKAA1_ST	P26358	DNMT1	Q13131	PRKAA1	S143	R139K	139	Missense	distal	-4	no	65.756	62.576	EPSD	ICGC;COSMIC	56.683	Down-regulation
CAMK_CAMKL_AMPK_PRKAA1_ST	P26358	DNMT1	Q13131	PRKAA1	S143	R139S	139	Missense	distal	-4	no	65.756	64.692	EPSD	ICGC;COSMIC	56.683	Down-regulation
CAMK_CAMKL_AMPK_PRKAA1_ST	P26358	DNMT1	Q13131	PRKAA1	S143	A147T	147	Missense	distal	4	no	65.756	63.188	EPSD	ICGC	56.683	Down-regulation
CAMK_CAMKL_AMPK_PRKAA1_ST	P26358	DNMT1	Q13131	PRKAA1	S143	R136H	136	Missense	distal	-7	no	65.756	62.732	EPSD	ICGC;COSMIC	56.683	Down-regulation
CAMK_CAMKL_AMPK_PRKAA1_ST	Q00613	HSF1	Q13131	PRKAA1	S230	P223L	223	Missense	distal	-7	no	64.109	63.948	EPSD	ICGC	56.683	Down-regulation
CAMK_CAMKL_AMPK_PRKAA1_ST	Q00613	HSF1	Q13131	PRKAA1	S244	P239L	239	Missense	distal	-5	no	59.384	64.124	EPSD	ICGC;CCLE	56.683	Up-regulation
CAMK_CAMKL_AMPK_PRKAA1_ST	Q00613	HSF1	Q13131	PRKAA1	S438	A437S	437	Missense	proximal	-1	no	60.281	60.259	EPSD	ICGC;COSMIC	56.683	Down-regulation
CAMK_CAMKL_AMPK_PRKAA1_ST	Q00613	HSF1	Q13131	PRKAA1	S438	S435N	435	Missense	distal	-3	no	60.281	63.740	EPSD	ICGC;COSMIC	56.683	Up-regulation
CAMK_CAMKL_AMPK_PRKAA1_ST	Q16875	PFKFB3	Q13131	PRKAA1	S22	V17I	17	Missense	distal	-5	no	53.235	58.677	EPSD	ICGC;COSMIC	56.683	Gain
CAMK_CAMKL_AMPK_PRKAA1_ST	Q16875	PFKFB3	Q13131	PRKAA1	S22	V17M	17	Missense	distal	-5	no	53.235	57.931	EPSD	ICGC;COSMIC	56.683	Gain
CAMK_CAMKL_AMPK_PRKAA1_ST	Q16875	PFKFB3	Q13131	PRKAA1	S211	D209Y	209	Missense	proximal	-2	no	63.029	63.178	EPSD	ICGC	56.683	Up-regulation
CAMK_CAMKL_AMPK_PRKAA1_ST	Q16875	PFKFB3	Q13131	PRKAA1	T359	R356H	356	Missense	distal	-3	no	57.676	49.820	EPSD	ICGC;COSMIC	56.683	Loss
CAMK_CAMKL_AMPK_PRKAA1_ST	Q9P2M7	CGN	Q13131	PRKAA1	S22	E25K	25	Missense	distal	3	no	62.293	64.017	EPSD	ICGC	56.683	Up-regulation
CAMK_CAMKL_AMPK_PRKAA1_ST	Q9P2M7	CGN	Q13131	PRKAA1	T394	Q389L	389	Missense	distal	-5	no	50.703	57.562	EPSD	ICGC	56.683	Gain
CAMK_CAMKL_AMPK_PRKAA1_ST	Q8IXJ6	SIRT2	Q13131	PRKAA1	S100	G102S	102	Missense	proximal	2	no	56.799	57.308	EPSD	ICGC;COSMIC	56.683	Up-regulation
CAMK_CAMKL_AMPK_PRKAA1_ST	Q8IXJ6	SIRT2	Q13131	PRKAA1	S100	F96L	96	Missense	distal	-4	no	56.799	57.151	EPSD	ICGC;COSMIC	56.683	Up-regulation
CAMK_CAMKL_AMPK_PRKAA1_ST	Q8IXJ6	SIRT2	Q13131	PRKAA1	S100	P99Q	99	Missense	proximal	-1	no	56.799	56.840	EPSD	ICGC	56.683	Up-regulation
CAMK_CAMKL_AMPK_PRKAA1_ST	Q8IXJ6	SIRT2	Q13131	PRKAA1	T101	G102S	102	Missense	proximal	1	no	58.596	58.009	PhosphoSitePlus	ICGC;COSMIC	56.683	Down-regulation
CAMK_CAMKL_AMPK_PRKAA1_ST	Q8IXJ6	SIRT2	Q13131	PRKAA1	T101	F96L	96	Missense	distal	-5	no	58.596	64.120	PhosphoSitePlus	ICGC;COSMIC	56.683	Up-regulation
CAMK_CAMKL_AMPK_PRKAA1_ST	Q8IXJ6	SIRT2	Q13131	PRKAA1	T101	P99Q	99	Missense	proximal	-2	no	58.596	57.270	PhosphoSitePlus	ICGC	56.683	Down-regulation
CAMK_CAMKL_AMPK_PRKAA1_ST	P14859	POU2F1	Q13131	PRKAA1	S78	S78L	78	Missense	central	0	yes	57.356	0.000	EPSD	ICGC;COSMIC	56.683	Loss
CAMK_CAMKL_AMPK_PRKAA1_ST	P14859	POU2F1	Q13131	PRKAA1	S78	S85I	85	Missense	distal	7	no	57.356	56.264	EPSD	ICGC	56.683	Loss
CAMK_CAMKL_AMPK_PRKAA1_ST	P14859	POU2F1	Q13131	PRKAA1	S78	Q71H	71	Missense	distal	-7	no	57.356	54.155	EPSD	ICGC;COSMIC	56.683	Loss
CAMK_CAMKL_AMPK_PRKAA1_ST	P14859	POU2F1	Q13131	PRKAA1	S335	K337N	337	Missense	proximal	2	no	69.234	68.780	PhosphoSitePlus	ICGC;COSMIC	56.683	Down-regulation
CAMK_CAMKL_AMPK_PRKAA1_ST	P14859	POU2F1	Q13131	PRKAA1	S335	R328Q	328	Missense	distal	-7	no	69.234	69.411	PhosphoSitePlus	ICGC;COSMIC;GDSC;CCLE	56.683	Up-regulation
CAMK_CAMKL_AMPK_PRKAA1_ST	P14859	POU2F1	Q13131	PRKAA1	S335	K341N	341	Missense	distal	6	no	69.234	69.171	PhosphoSitePlus	ICGC;COSMIC	56.683	Down-regulation
CAMK_CAMKL_AMPK_PRKAA1_ST	P14859	POU2F1	Q13131	PRKAA1	S335	R328L	328	Missense	distal	-7	no	69.234	67.801	PhosphoSitePlus	ICGC;COSMIC	56.683	Down-regulation
CAMK_CAMKL_AMPK_PRKAA1_ST	P14859	POU2F1	Q13131	PRKAA1	S357	S360L	360	Missense	distal	3	no	57.021	55.039	EPSD	ICGC;COSMIC;GDSC	56.683	Loss
CAMK_CAMKL_AMPK_PRKAA1_ST	P14859	POU2F1	Q13131	PRKAA1	S357	D352N	352	Missense	distal	-5	no	57.021	42.945	EPSD	ICGC;COSMIC	56.683	Loss
CAMK_CAMKL_AMPK_PRKAA1_ST	P14859	POU2F1	Q13131	PRKAA1	S358	S360L	360	Missense	proximal	2	no	67.866	67.810	EPSD	ICGC;COSMIC;GDSC	56.683	Down-regulation
CAMK_CAMKL_AMPK_PRKAA1_ST	P14859	POU2F1	Q13131	PRKAA1	S358	D352N	352	Missense	distal	-6	no	67.866	65.601	EPSD	ICGC;COSMIC	56.683	Down-regulation
CAMK_CAMKL_AMPK_PRKAA1_ST	P14859	POU2F1	Q13131	PRKAA1	S377	R378H	378	Missense	proximal	1	no	54.041	57.039	EPSD	ICGC;COSMIC	56.683	Gain
CAMK_CAMKL_AMPK_PRKAA1_ST	P14859	POU2F1	Q13131	PRKAA1	T384	E387D	387	Missense	distal	3	no	58.007	59.717	EPSD	ICGC;COSMIC	56.683	Up-regulation
CAMK_CAMKL_AMPK_PRKAA1_ST	P14859	POU2F1	Q13131	PRKAA1	T384	R383H	383	Missense	proximal	-1	no	58.007	58.027	EPSD	ICGC;COSMIC	56.683	Up-regulation
CAMK_CAMKL_AMPK_PRKAA1_ST	P14859	POU2F1	Q13131	PRKAA1	T384	R391L	391	Missense	distal	7	no	58.007	58.635	EPSD	ICGC;COSMIC	56.683	Up-regulation
CAMK_CAMKL_AMPK_PRKAA1_ST	P14859	POU2F1	Q13131	PRKAA1	T384	R378C	378	Missense	distal	-6	no	58.007	53.931	EPSD	ICGC;COSMIC	56.683	Loss
CAMK_CAMKL_AMPK_PRKAA1_ST	P14859	POU2F1	Q13131	PRKAA1	T384	S385N	385	Missense	proximal	1	no	58.007	57.154	EPSD	ICGC;COSMIC	56.683	Down-regulation
CAMK_CAMKL_AMPK_PRKAA1_ST	P14859	POU2F1	Q13131	PRKAA1	T384	R378H	378	Missense	distal	-6	no	58.007	56.474	EPSD	ICGC;COSMIC	56.683	Loss
CAMK_CAMKL_AMPK_PRKAA1_ST	P14859	POU2F1	Q13131	PRKAA1	T384	R391C	391	Missense	distal	7	no	58.007	58.041	EPSD	ICGC;COSMIC	56.683	Up-regulation
CAMK_CAMKL_AMPK_PRKAA1_ST	Q14247	CTTN	Q13131	PRKAA1	S113	V115L	115	Missense	proximal	2	no	59.382	58.380	EPSD	ICGC	56.683	Down-regulation
CAMK_CAMKL_AMPK_PRKAA1_ST	Q14247	CTTN	Q13131	PRKAA1	S113	G120C	120	Missense	distal	7	no	59.382	58.880	EPSD	ICGC	56.683	Down-regulation
CAMK_CAMKL_AMPK_PRKAA1_ST	Q14247	CTTN	Q13131	PRKAA1	S113	Q114H	114	Missense	proximal	1	no	59.382	63.259	EPSD	ICGC	56.683	Up-regulation
CAMK_CAMKL_AMPK_PRKAA1_ST	Q14247	CTTN	Q13131	PRKAA1	S282	D288N	288	Missense	distal	6	no	65.321	65.503	EPSD	ICGC;COSMIC	56.683	Up-regulation
CAMK_CAMKL_AMPK_PRKAA1_ST	Q14247	CTTN	Q13131	PRKAA1	S282	A283V	283	Missense	proximal	1	no	65.321	66.780	EPSD	ICGC;COSMIC	56.683	Up-regulation
CAMK_CAMKL_AMPK_PRKAA1_ST	Q14247	CTTN	Q13131	PRKAA1	S282	D288H	288	Missense	distal	6	no	65.321	65.619	EPSD	ICGC;COSMIC	56.683	Up-regulation
CAMK_CAMKL_AMPK_PRKAA1_ST	Q14247	CTTN	Q13131	PRKAA1	S282	V275F	275	Missense	distal	-7	no	65.321	64.107	EPSD	ICGC;COSMIC	56.683	Down-regulation
CAMK_CAMKL_AMPK_PRKAA1_ST	Q14247	CTTN	Q13131	PRKAA1	S282	S282F	282	Missense	central	0	yes	65.321	0.000	EPSD	ICGC	56.683	Loss
CAMK_CAMKL_AMPK_PRKAA1_ST	Q14247	CTTN	Q13131	PRKAA1	S282	E278D	278	Missense	distal	-4	no	65.321	65.282	EPSD	ICGC	56.683	Down-regulation
CAMK_CAMKL_AMPK_PRKAA1_ST	Q14247	CTTN	Q13131	PRKAA1	T401	T401M	401	Missense	central	0	yes	59.063	0.000	PhosphoSitePlus	ICGC;COSMIC	56.683	Loss
CAMK_CAMKL_AMPK_PRKAA1_ST	Q14247	CTTN	Q13131	PRKAA1	T401	T401A	401	Missense	central	0	yes	59.063	0.000	PhosphoSitePlus	ICGC	56.683	Loss
CAMK_CAMKL_AMPK_PRKAA1_ST	Q14247	CTTN	Q13131	PRKAA1	T401	S405L	405	Missense	distal	4	no	59.063	65.651	PhosphoSitePlus	ICGC;COSMIC;GDSC	56.683	Up-regulation
CAMK_CAMKL_AMPK_PRKAA1_ST	Q14247	CTTN	Q13131	PRKAA1	T401	A407T	407	Missense	distal	6	no	59.063	58.903	PhosphoSitePlus	ICGC;COSMIC	56.683	Down-regulation
CAMK_CAMKL_AMPK_PRKAA1_ST	Q14247	CTTN	Q13131	PRKAA1	S417	E412K	412	Missense	distal	-5	no	57.091	54.444	EPSD	ICGC;COSMIC	56.683	Loss
CAMK_CAMKL_AMPK_PRKAA1_ST	Q14247	CTTN	Q13131	PRKAA1	S417	L415P	415	Missense	proximal	-2	no	57.091	60.066	EPSD	ICGC	56.683	Up-regulation
CAMK_CAMKL_AMPK_PRKAA1_ST	Q14247	CTTN	Q13131	PRKAA1	S417	A424V	424	Missense	distal	7	no	57.091	54.673	EPSD	ICGC;COSMIC;GDSC	56.683	Loss
CAMK_CAMKL_AMPK_PRKAA1_ST	Q14247	CTTN	Q13131	PRKAA1	S447	A450G	450	Missense	distal	3	no	52.854	58.036	EPSD	ICGC;COSMIC	56.683	Gain
CAMK_CAMKL_AMPK_PRKAA1_ST	Q14247	CTTN	Q13131	PRKAA1	S447	A450V	450	Missense	distal	3	no	52.854	57.731	EPSD	ICGC;COSMIC	56.683	Gain
CAMK_CAMKL_AMPK_PRKAA1_ST	P15056	BRAF	Q13131	PRKAA1	S151	N148S	148	Missense	distal	-3	no	59.762	56.303	EPSD	ICGC;COSMIC	56.683	Loss
CAMK_CAMKL_AMPK_PRKAA1_ST	P15056	BRAF	Q13131	PRKAA1	S151	P152S	152	Missense	proximal	1	no	59.762	60.395	EPSD	ICGC;COSMIC	56.683	Up-regulation
CAMK_CAMKL_AMPK_PRKAA1_ST	P15056	BRAF	Q13131	PRKAA1	S151	S147R	147	Missense	distal	-4	no	59.762	60.826	EPSD	ICGC	56.683	Up-regulation
CAMK_CAMKL_AMPK_PRKAA1_ST	P15056	BRAF	Q13131	PRKAA1	S151	P152T	152	Missense	proximal	1	no	59.762	59.352	EPSD	ICGC	56.683	Down-regulation
CAMK_CAMKL_AMPK_PRKAA1_ST	P15056	BRAF	Q13131	PRKAA1	S363	Q359K	359	Missense	distal	-4	no	60.159	58.448	EPSD	ICGC	56.683	Down-regulation
CAMK_CAMKL_AMPK_PRKAA1_ST	P15056	BRAF	Q13131	PRKAA1	S363	S363F	363	Missense	central	0	yes	60.159	0.000	EPSD	ICGC;COSMIC	56.683	Loss
CAMK_CAMKL_AMPK_PRKAA1_ST	P15056	BRAF	Q13131	PRKAA1	S363	P367L	367	Missense	distal	4	no	60.159	66.899	EPSD	ICGC;COSMIC	56.683	Up-regulation
CAMK_CAMKL_AMPK_PRKAA1_ST	P15056	BRAF	Q13131	PRKAA1	S363	Q359R	359	Missense	distal	-4	no	60.159	61.628	EPSD	ICGC;COSMIC	56.683	Up-regulation
CAMK_CAMKL_AMPK_PRKAA1_ST	P15056	BRAF	Q13131	PRKAA1	S365	N372K	372	Missense	distal	7	no	71.119	69.345	EPSD	ICGC	56.683	Down-regulation
CAMK_CAMKL_AMPK_PRKAA1_ST	P15056	BRAF	Q13131	PRKAA1	S365	Q359K	359	Missense	distal	-6	no	71.119	69.280	EPSD	ICGC	56.683	Down-regulation
CAMK_CAMKL_AMPK_PRKAA1_ST	P15056	BRAF	Q13131	PRKAA1	S365	S363F	363	Missense	proximal	-2	no	71.119	68.921	EPSD	ICGC;COSMIC	56.683	Down-regulation
CAMK_CAMKL_AMPK_PRKAA1_ST	P15056	BRAF	Q13131	PRKAA1	S365	P367L	367	Missense	proximal	2	no	71.119	70.519	EPSD	ICGC;COSMIC	56.683	Down-regulation
CAMK_CAMKL_AMPK_PRKAA1_ST	P15056	BRAF	Q13131	PRKAA1	S365	Q359R	359	Missense	distal	-6	no	71.119	70.762	EPSD	ICGC;COSMIC	56.683	Down-regulation
CAMK_CAMKL_AMPK_PRKAA1_ST	P15056	BRAF	Q13131	PRKAA1	S430	S429Y	429	Missense	proximal	-1	no	63.157	63.270	EPSD	ICGC	56.683	Up-regulation
CAMK_CAMKL_AMPK_PRKAA1_ST	P15056	BRAF	Q13131	PRKAA1	S430	Q423H	423	Missense	distal	-7	no	63.157	59.956	EPSD	ICGC;COSMIC	56.683	Down-regulation
CAMK_CAMKL_AMPK_PRKAA1_ST	P15056	BRAF	Q13131	PRKAA1	S430	S428T	428	Missense	proximal	-2	no	63.157	60.474	EPSD	ICGC;COSMIC	56.683	Down-regulation
CAMK_CAMKL_AMPK_PRKAA1_ST	P15056	BRAF	Q13131	PRKAA1	T440	R444Q	444	Missense	distal	4	no	58.124	54.041	EPSD	ICGC;COSMIC	56.683	Loss
CAMK_CAMKL_AMPK_PRKAA1_ST	P15056	BRAF	Q13131	PRKAA1	T440	R444W	444	Missense	distal	4	no	58.124	61.375	EPSD	ICGC;COSMIC	56.683	Up-regulation
CAMK_CAMKL_AMPK_PRKAA1_ST	P15056	BRAF	Q13131	PRKAA1	T440	T440K	440	Missense	central	0	yes	58.124	0.000	EPSD	ICGC	56.683	Loss
CAMK_CAMKL_AMPK_PRKAA1_ST	P15056	BRAF	Q13131	PRKAA1	T440	L441I	441	Missense	proximal	1	no	58.124	57.471	EPSD	ICGC;COSMIC	56.683	Down-regulation
CAMK_CAMKL_AMPK_PRKAA1_ST	P15056	BRAF	Q13131	PRKAA1	T440	S446L	446	Missense	distal	6	no	58.124	58.257	EPSD	ICGC;COSMIC	56.683	Up-regulation
CAMK_CAMKL_AMPK_PRKAA1_ST	P15056	BRAF	Q13131	PRKAA1	T440	M438I	438	Missense	proximal	-2	no	58.124	58.660	EPSD	ICGC;COSMIC	56.683	Up-regulation
CAMK_CAMKL_AMPK_PRKAA1_ST	P15056	BRAF	Q13131	PRKAA1	S446	R444Q	444	Missense	proximal	-2	no	72.355	72.818	EPSD	ICGC;COSMIC	56.683	Up-regulation
CAMK_CAMKL_AMPK_PRKAA1_ST	P15056	BRAF	Q13131	PRKAA1	S446	R444W	444	Missense	proximal	-2	no	72.355	70.016	EPSD	ICGC;COSMIC	56.683	Down-regulation
CAMK_CAMKL_AMPK_PRKAA1_ST	P15056	BRAF	Q13131	PRKAA1	S446	T440K	440	Missense	distal	-6	no	72.355	70.879	EPSD	ICGC	56.683	Down-regulation
CAMK_CAMKL_AMPK_PRKAA1_ST	P15056	BRAF	Q13131	PRKAA1	S446	L441I	441	Missense	distal	-5	no	72.355	72.934	EPSD	ICGC;COSMIC	56.683	Up-regulation
CAMK_CAMKL_AMPK_PRKAA1_ST	P15056	BRAF	Q13131	PRKAA1	S446	E451D	451	Missense	distal	5	no	72.355	72.508	EPSD	ICGC;COSMIC	56.683	Up-regulation
CAMK_CAMKL_AMPK_PRKAA1_ST	P15056	BRAF	Q13131	PRKAA1	S446	S446L	446	Missense	central	0	yes	72.355	0.000	EPSD	ICGC;COSMIC	56.683	Loss
CAMK_CAMKL_AMPK_PRKAA1_ST	P15056	BRAF	Q13131	PRKAA1	S447	R444Q	444	Missense	distal	-3	no	63.427	55.483	EPSD	ICGC;COSMIC	56.683	Loss
CAMK_CAMKL_AMPK_PRKAA1_ST	P15056	BRAF	Q13131	PRKAA1	S447	R444W	444	Missense	distal	-3	no	63.427	-29.573	EPSD	ICGC;COSMIC	56.683	Loss
CAMK_CAMKL_AMPK_PRKAA1_ST	P15056	BRAF	Q13131	PRKAA1	S447	T440K	440	Missense	distal	-7	no	63.427	65.888	EPSD	ICGC	56.683	Up-regulation
CAMK_CAMKL_AMPK_PRKAA1_ST	P15056	BRAF	Q13131	PRKAA1	S447	L441I	441	Missense	distal	-6	no	63.427	60.443	EPSD	ICGC;COSMIC	56.683	Down-regulation
CAMK_CAMKL_AMPK_PRKAA1_ST	P15056	BRAF	Q13131	PRKAA1	S447	E451D	451	Missense	distal	4	no	63.427	67.344	EPSD	ICGC;COSMIC	56.683	Up-regulation
CAMK_CAMKL_AMPK_PRKAA1_ST	P15056	BRAF	Q13131	PRKAA1	S447	S446L	446	Missense	proximal	-1	no	63.427	63.453	EPSD	ICGC;COSMIC	56.683	Up-regulation
CAMK_CAMKL_AMPK_PRKAA1_ST	P15056	BRAF	Q13131	PRKAA1	S720	R726H	726	Missense	distal	6	no	61.501	61.606	EPSD	ICGC;COSMIC	56.683	Up-regulation
CAMK_CAMKL_AMPK_PRKAA1_ST	P15056	BRAF	Q13131	PRKAA1	S720	I724M	724	Missense	distal	4	no	61.501	62.001	EPSD	ICGC	56.683	Up-regulation
CAMK_CAMKL_AMPK_PRKAA1_ST	P15056	BRAF	Q13131	PRKAA1	S720	S727G	727	Missense	distal	7	no	61.501	61.450	EPSD	ICGC;COSMIC;GDSC;CCLE	56.683	Down-regulation
CAMK_CAMKL_AMPK_PRKAA1_ST	P15056	BRAF	Q13131	PRKAA1	S729	R726H	726	Missense	distal	-3	no	73.936	66.079	PhosphoSitePlus	ICGC;COSMIC	56.683	Down-regulation
CAMK_CAMKL_AMPK_PRKAA1_ST	P15056	BRAF	Q13131	PRKAA1	S729	I724M	724	Missense	distal	-5	no	73.936	73.189	PhosphoSitePlus	ICGC	56.683	Down-regulation
CAMK_CAMKL_AMPK_PRKAA1_ST	P15056	BRAF	Q13131	PRKAA1	S729	E730D	730	Missense	proximal	1	no	73.936	74.148	PhosphoSitePlus	ICGC	56.683	Up-regulation
CAMK_CAMKL_AMPK_PRKAA1_ST	P15056	BRAF	Q13131	PRKAA1	S729	S727G	727	Missense	proximal	-2	no	73.936	70.631	PhosphoSitePlus	ICGC;COSMIC;GDSC;CCLE	56.683	Down-regulation
CAMK_CAMKL_AMPK_PRKAA1_ST	Q12778	FOXO1	Q13131	PRKAA1	S22	P28L	28	Missense	distal	6	no	62.002	62.150	EPSD	ICGC;COSMIC	56.683	Up-regulation
CAMK_CAMKL_AMPK_PRKAA1_ST	Q12778	FOXO1	Q13131	PRKAA1	S22	T24A	24	Missense	proximal	2	no	62.002	61.556	EPSD	ICGC;COSMIC	56.683	Down-regulation
CAMK_CAMKL_AMPK_PRKAA1_ST	Q12778	FOXO1	Q13131	PRKAA1	S22	R19Q	19	Missense	distal	-3	no	62.002	54.058	EPSD	ICGC;COSMIC	56.683	Loss
CAMK_CAMKL_AMPK_PRKAA1_ST	Q12778	FOXO1	Q13131	PRKAA1	S22	T24I	24	Missense	proximal	2	no	62.002	61.143	EPSD	ICGC;COSMIC;CCLE	56.683	Down-regulation
CAMK_CAMKL_AMPK_PRKAA1_ST	Q12778	FOXO1	Q13131	PRKAA1	S22	P26S	26	Missense	distal	4	no	62.002	62.154	EPSD	ICGC;COSMIC	56.683	Up-regulation
CAMK_CAMKL_AMPK_PRKAA1_ST	Q12778	FOXO1	Q13131	PRKAA1	S22	R21C	21	Missense	proximal	-1	no	62.002	62.149	EPSD	ICGC;COSMIC;CCLE	56.683	Up-regulation
CAMK_CAMKL_AMPK_PRKAA1_ST	Q12778	FOXO1	Q13131	PRKAA1	S22	R21H	21	Missense	proximal	-1	no	62.002	62.021	EPSD	ICGC;COSMIC	56.683	Up-regulation
CAMK_CAMKL_AMPK_PRKAA1_ST	Q12778	FOXO1	Q13131	PRKAA1	S22	R21P	21	Missense	proximal	-1	no	62.002	61.989	EPSD	ICGC;COSMIC;CCLE	56.683	Down-regulation
CAMK_CAMKL_AMPK_PRKAA1_ST	Q12778	FOXO1	Q13131	PRKAA1	S22	R19W	19	Missense	distal	-3	no	62.002	-30.998	EPSD	ICGC;COSMIC;CCLE	56.683	Loss
CAMK_CAMKL_AMPK_PRKAA1_ST	Q12778	FOXO1	Q13131	PRKAA1	S22	S22P	22	Missense	central	0	yes	62.002	0.000	EPSD	ICGC;COSMIC;CCLE	56.683	Loss
CAMK_CAMKL_AMPK_PRKAA1_ST	Q12778	FOXO1	Q13131	PRKAA1	T24	P28L	28	Missense	distal	4	no	60.529	67.269	EPSD	ICGC;COSMIC	56.683	Up-regulation
CAMK_CAMKL_AMPK_PRKAA1_ST	Q12778	FOXO1	Q13131	PRKAA1	T24	S22T	22	Missense	proximal	-2	no	60.529	57.846	EPSD	ICGC	56.683	Down-regulation
CAMK_CAMKL_AMPK_PRKAA1_ST	Q12778	FOXO1	Q13131	PRKAA1	T24	T24A	24	Missense	central	0	yes	60.529	0.000	EPSD	ICGC;COSMIC	56.683	Loss
CAMK_CAMKL_AMPK_PRKAA1_ST	Q12778	FOXO1	Q13131	PRKAA1	T24	R19Q	19	Missense	distal	-5	no	60.529	54.847	EPSD	ICGC;COSMIC	56.683	Loss
CAMK_CAMKL_AMPK_PRKAA1_ST	Q12778	FOXO1	Q13131	PRKAA1	T24	T24I	24	Missense	central	0	yes	60.529	0.000	EPSD	ICGC;COSMIC;CCLE	56.683	Loss
CAMK_CAMKL_AMPK_PRKAA1_ST	Q12778	FOXO1	Q13131	PRKAA1	T24	P26S	26	Missense	proximal	2	no	60.529	59.985	EPSD	ICGC;COSMIC	56.683	Down-regulation
CAMK_CAMKL_AMPK_PRKAA1_ST	Q12778	FOXO1	Q13131	PRKAA1	T24	R21C	21	Missense	distal	-3	no	60.529	46.381	EPSD	ICGC;COSMIC;CCLE	56.683	Loss
CAMK_CAMKL_AMPK_PRKAA1_ST	Q12778	FOXO1	Q13131	PRKAA1	T24	R21H	21	Missense	distal	-3	no	60.529	52.672	EPSD	ICGC;COSMIC	56.683	Loss
CAMK_CAMKL_AMPK_PRKAA1_ST	Q12778	FOXO1	Q13131	PRKAA1	T24	R21P	21	Missense	distal	-3	no	60.529	51.669	EPSD	ICGC;COSMIC;CCLE	56.683	Loss
CAMK_CAMKL_AMPK_PRKAA1_ST	Q12778	FOXO1	Q13131	PRKAA1	T24	R19W	19	Missense	distal	-5	no	60.529	55.336	EPSD	ICGC;COSMIC;CCLE	56.683	Loss
CAMK_CAMKL_AMPK_PRKAA1_ST	Q12778	FOXO1	Q13131	PRKAA1	T24	S22P	22	Missense	proximal	-2	no	60.529	61.078	EPSD	ICGC;COSMIC;CCLE	56.683	Up-regulation
CAMK_CAMKL_AMPK_PRKAA1_ST	Q12778	FOXO1	Q13131	PRKAA1	S205	G208D	208	Missense	distal	3	no	57.171	56.709	EPSD	ICGC;COSMIC;GDSC;CCLE	56.683	Down-regulation
CAMK_CAMKL_AMPK_PRKAA1_ST	Q12778	FOXO1	Q13131	PRKAA1	S218	L219I	219	Missense	proximal	1	no	57.131	56.478	EPSD	ICGC;COSMIC	56.683	Loss
CAMK_CAMKL_AMPK_PRKAA1_ST	Q12778	FOXO1	Q13131	PRKAA1	S256	D258E	258	Missense	proximal	2	no	64.482	64.443	EPSD	ICGC	56.683	Down-regulation
CAMK_CAMKL_AMPK_PRKAA1_ST	Q12778	FOXO1	Q13131	PRKAA1	S290	A284D	284	Missense	distal	-6	no	55.036	56.753	EPSD	ICGC	56.683	Gain
CAMK_CAMKL_AMPK_PRKAA1_ST	Q12778	FOXO1	Q13131	PRKAA1	S319	G326V	326	Missense	distal	7	no	64.829	62.590	EPSD	ICGC;COSMIC	56.683	Down-regulation
CAMK_CAMKL_AMPK_PRKAA1_ST	Q12778	FOXO1	Q13131	PRKAA1	S329	E334K	334	Missense	distal	5	no	59.724	59.745	EPSD	ICGC;COSMIC;CCLE	56.683	Up-regulation
CAMK_CAMKL_AMPK_PRKAA1_ST	Q12778	FOXO1	Q13131	PRKAA1	S329	G326V	326	Missense	distal	-3	no	59.724	60.344	EPSD	ICGC;COSMIC	56.683	Up-regulation
CAMK_CAMKL_AMPK_PRKAA1_ST	Q12778	FOXO1	Q13131	PRKAA1	T333	E334K	334	Missense	proximal	1	no	60.509	61.438	EPSD	ICGC;COSMIC;CCLE	56.683	Up-regulation
CAMK_CAMKL_AMPK_PRKAA1_ST	Q12778	FOXO1	Q13131	PRKAA1	T333	G326V	326	Missense	distal	-7	no	60.509	58.711	EPSD	ICGC;COSMIC	56.683	Down-regulation
CAMK_CAMKL_AMPK_PRKAA1_ST	Q12778	FOXO1	Q13131	PRKAA1	S345	M346T	346	Missense	proximal	1	no	57.965	54.880	EPSD	ICGC;COSMIC	56.683	Loss
CAMK_CAMKL_AMPK_PRKAA1_ST	Q12778	FOXO1	Q13131	PRKAA1	S345	P349Q	349	Missense	distal	4	no	57.965	55.140	EPSD	ICGC;COSMIC	56.683	Loss
CAMK_CAMKL_AMPK_PRKAA1_ST	Q12778	FOXO1	Q13131	PRKAA1	T649	S651R	651	Missense	proximal	2	no	56.935	57.029	PhosphoSitePlus	ICGC	56.683	Up-regulation
CAMK_CAMKL_AMPK_PRKAA1_ST	Q12778	FOXO1	Q13131	PRKAA1	T649	T649A	649	Missense	central	0	yes	56.935	0.000	PhosphoSitePlus	ICGC	56.683	Loss
CAMK_CAMKL_AMPK_PRKAA1_ST	P43405	SYK	Q13131	PRKAA1	S93	V100I	100	Missense	distal	7	no	55.925	57.123	EPSD	ICGC;COSMIC	56.683	Gain
CAMK_CAMKL_AMPK_PRKAA1_ST	P43405	SYK	Q13131	PRKAA1	S178	R175W	175	Missense	distal	-3	no	65.506	-27.494	PhosphoSitePlus	ICGC;COSMIC	56.683	Loss
CAMK_CAMKL_AMPK_PRKAA1_ST	P43405	SYK	Q13131	PRKAA1	S295	P299L	299	Missense	distal	4	no	60.446	67.186	EPSD	ICGC;COSMIC	56.683	Up-regulation
CAMK_CAMKL_AMPK_PRKAA1_ST	P43405	SYK	Q13131	PRKAA1	S295	G302D	302	Missense	distal	7	no	60.446	59.277	EPSD	ICGC;COSMIC	56.683	Down-regulation
CAMK_CAMKL_AMPK_PRKAA1_ST	P43405	SYK	Q13131	PRKAA1	S295	P299S	299	Missense	distal	4	no	60.446	60.598	EPSD	ICGC;COSMIC	56.683	Up-regulation
CAMK_CAMKL_AMPK_PRKAA1_ST	P43405	SYK	Q13131	PRKAA1	S297	P299L	299	Missense	proximal	2	no	61.680	61.080	EPSD	ICGC;COSMIC	56.683	Down-regulation
CAMK_CAMKL_AMPK_PRKAA1_ST	P43405	SYK	Q13131	PRKAA1	S297	G302D	302	Missense	distal	5	no	61.680	61.831	EPSD	ICGC;COSMIC	56.683	Up-regulation
CAMK_CAMKL_AMPK_PRKAA1_ST	P43405	SYK	Q13131	PRKAA1	S297	P299S	299	Missense	proximal	2	no	61.680	61.136	EPSD	ICGC;COSMIC	56.683	Down-regulation
CAMK_CAMKL_AMPK_PRKAA1_ST	P43405	SYK	Q13131	PRKAA1	S297	H303N	303	Missense	distal	6	no	61.680	61.563	EPSD	ICGC;COSMIC	56.683	Down-regulation
CAMK_CAMKL_AMPK_PRKAA1_ST	P43405	SYK	Q13131	PRKAA1	S307	K305R	305	Missense	proximal	-2	no	57.039	55.661	EPSD	ICGC	56.683	Loss
CAMK_CAMKL_AMPK_PRKAA1_ST	P43405	SYK	Q13131	PRKAA1	S307	G302D	302	Missense	distal	-5	no	57.039	56.189	EPSD	ICGC;COSMIC	56.683	Loss
CAMK_CAMKL_AMPK_PRKAA1_ST	P43405	SYK	Q13131	PRKAA1	S307	H303N	303	Missense	distal	-4	no	57.039	54.562	EPSD	ICGC;COSMIC	56.683	Loss
CAMK_CAMKL_AMPK_PRKAA1_ST	O00763	ACACB	Q13131	PRKAA1	S37	P43S	43	Missense	distal	6	no	68.031	68.046	EPSD	ICGC	56.683	Up-regulation
CAMK_CAMKL_AMPK_PRKAA1_ST	O00763	ACACB	Q13131	PRKAA1	S192	R193L	193	Missense	proximal	1	no	59.804	59.865	EPSD	ICGC;COSMIC;GDSC;CCLE	56.683	Up-regulation
CAMK_CAMKL_AMPK_PRKAA1_ST	O00763	ACACB	Q13131	PRKAA1	T216	G223E	223	Missense	distal	7	no	60.087	59.362	EPSD	ICGC;COSMIC	56.683	Down-regulation
CAMK_CAMKL_AMPK_PRKAA1_ST	O00763	ACACB	Q13131	PRKAA1	T216	P215S	215	Missense	proximal	-1	no	60.087	60.132	EPSD	ICGC;COSMIC	56.683	Up-regulation
CAMK_CAMKL_AMPK_PRKAA1_ST	O00763	ACACB	Q13131	PRKAA1	S222	G223E	223	Missense	proximal	1	no	62.768	61.129	PhosphoSitePlus	ICGC;COSMIC	56.683	Down-regulation
CAMK_CAMKL_AMPK_PRKAA1_ST	O00763	ACACB	Q13131	PRKAA1	S222	P215S	215	Missense	distal	-7	no	62.768	65.035	PhosphoSitePlus	ICGC;COSMIC	56.683	Up-regulation
CAMK_CAMKL_AMPK_PRKAA1_ST	O00763	ACACB	Q13131	PRKAA1	T243	H239Y	239	Missense	distal	-4	no	58.555	58.017	EPSD	ICGC	56.683	Down-regulation
CAMK_CAMKL_AMPK_PRKAA1_ST	O00763	ACACB	Q13131	PRKAA1	T243	A248S	248	Missense	distal	5	no	58.555	58.509	EPSD	ICGC;COSMIC	56.683	Down-regulation
CAMK_CAMKL_AMPK_PRKAA1_ST	O00763	ACACB	Q13131	PRKAA1	S469	A470S	470	Missense	proximal	1	no	65.316	66.911	EPSD	ICGC	56.683	Up-regulation
CAMK_CAMKL_AMPK_PRKAA1_ST	O00763	ACACB	Q13131	PRKAA1	S1081	Q1082K	1082	Missense	proximal	1	no	57.172	58.917	EPSD	ICGC;COSMIC	56.683	Up-regulation
CAMK_CAMKL_AMPK_PRKAA1_ST	O00763	ACACB	Q13131	PRKAA1	S1620	V1627I	1627	Missense	distal	7	no	63.001	64.199	EPSD	ICGC	56.683	Up-regulation
CAMK_CAMKL_AMPK_PRKAA1_ST	Q13501	SQSTM1	Q13131	PRKAA1	S24	R21H	21	Missense	distal	-3	no	59.560	51.704	EPSD	ICGC;GDSC;CCLE	56.683	Loss
CAMK_CAMKL_AMPK_PRKAA1_ST	Q13501	SQSTM1	Q13131	PRKAA1	S24	R18L	18	Missense	distal	-6	no	59.560	59.400	EPSD	ICGC	56.683	Down-regulation
CAMK_CAMKL_AMPK_PRKAA1_ST	Q13501	SQSTM1	Q13131	PRKAA1	S24	P29S	29	Missense	distal	5	no	59.560	59.522	EPSD	ICGC;COSMIC	56.683	Down-regulation
CAMK_CAMKL_AMPK_PRKAA1_ST	Q13501	SQSTM1	Q13131	PRKAA1	T164	A167E	167	Missense	distal	3	no	55.073	58.084	EPSD	ICGC	56.683	Gain
CAMK_CAMKL_AMPK_PRKAA1_ST	Q13501	SQSTM1	Q13131	PRKAA1	S180	R186Q	186	Missense	distal	6	no	57.331	57.761	EPSD	ICGC;COSMIC	56.683	Up-regulation
CAMK_CAMKL_AMPK_PRKAA1_ST	Q13501	SQSTM1	Q13131	PRKAA1	S180	R183P	183	Missense	distal	3	no	57.331	55.744	EPSD	ICGC;COSMIC	56.683	Loss
CAMK_CAMKL_AMPK_PRKAA1_ST	Q13501	SQSTM1	Q13131	PRKAA1	S233	P232L	232	Missense	proximal	-1	no	58.665	58.736	EPSD	ICGC;COSMIC	56.683	Up-regulation
CAMK_CAMKL_AMPK_PRKAA1_ST	Q13501	SQSTM1	Q13131	PRKAA1	S233	S233I	233	Missense	central	0	yes	58.665	0.000	EPSD	ICGC	56.683	Loss
CAMK_CAMKL_AMPK_PRKAA1_ST	Q13501	SQSTM1	Q13131	PRKAA1	S284	S284L	284	Missense	central	0	yes	63.501	0.000	EPSD	ICGC;COSMIC	56.683	Loss
CAMK_CAMKL_AMPK_PRKAA1_ST	Q13501	SQSTM1	Q13131	PRKAA1	S294	P296L	296	Missense	proximal	2	no	64.675	64.075	PhosphoSitePlus	ICGC;COSMIC	56.683	Down-regulation
CAMK_CAMKL_AMPK_PRKAA1_ST	Q13501	SQSTM1	Q13131	PRKAA1	S294	G297C	297	Missense	distal	3	no	64.675	61.641	PhosphoSitePlus	ICGC	56.683	Down-regulation
CMGC_CDK_CRK7_CDK12_ST	P24928	POLR2A	Q9NYV4	CDK12	S217	E223A	223	Missense	distal	6	no	4.639	4.637	EPSD	ICGC	0.929	Down-regulation
CMGC_CDK_CRK7_CDK12_ST	P24928	POLR2A	Q9NYV4	CDK12	T368	S362L	362	Missense	distal	-6	no	4.124	4.112	EPSD	ICGC	0.929	Down-regulation
CMGC_CDK_CRK7_CDK12_ST	P24928	POLR2A	Q9NYV4	CDK12	S1532	G1529D	1529	Missense	distal	-3	no	4.196	4.170	EPSD	ICGC	0.929	Down-regulation
CMGC_CDK_CRK7_CDK12_ST	P24928	POLR2A	Q9NYV4	CDK12	T1568	W1565C	1565	Missense	distal	-3	no	5.189	5.190	EPSD	ICGC	0.929	Up-regulation
CMGC_CDK_CRK7_CDK12_ST	P24928	POLR2A	Q9NYV4	CDK12	T1568	G1570D	1570	Missense	proximal	2	no	5.189	5.258	EPSD	ICGC	0.929	Up-regulation
CMGC_CDK_CRK7_CDK12_ST	P24928	POLR2A	Q9NYV4	CDK12	S1571	G1570D	1570	Missense	proximal	-1	no	5.658	5.635	EPSD	ICGC	0.929	Down-regulation
CMGC_CDK_CRK7_CDK12_ST	P24928	POLR2A	Q9NYV4	CDK12	S1574	G1570D	1570	Missense	distal	-4	no	4.953	5.078	EPSD	ICGC	0.929	Up-regulation
CMGC_CDK_CRK7_CDK12_ST	P24928	POLR2A	Q9NYV4	CDK12	S1619	T1625P	1625	Missense	distal	6	no	3.907	3.897	EPSD;PhosphoSitePlus	ICGC	0.929	Down-regulation
CMGC_CDK_CRK7_CDK12_ST	P24928	POLR2A	Q9NYV4	CDK12	S1621	T1625P	1625	Missense	distal	4	no	1.088	1.594	EPSD	ICGC	0.929	Up-regulation
CMGC_CDK_CRK7_CDK12_ST	P24928	POLR2A	Q9NYV4	CDK12	S1626	T1625P	1625	Missense	proximal	-1	no	4.368	4.299	EPSD	ICGC	0.929	Down-regulation
CMGC_CDK_CRK7_CDK12_ST	P24928	POLR2A	Q9NYV4	CDK12	S1647	S1644L	1644	Missense	distal	-3	no	4.366	4.324	EPSD	ICGC	0.929	Down-regulation
CMGC_CDK_CRK7_CDK12_ST	P24928	POLR2A	Q9NYV4	CDK12	S1661	S1665P	1665	Missense	distal	4	no	4.328	4.775	EPSD	ICGC	0.929	Up-regulation
CMGC_CDK_CRK7_CDK12_ST	P24928	POLR2A	Q9NYV4	CDK12	S1663	S1665P	1665	Missense	proximal	2	no	0.786	1.062	EPSD	ICGC	0.929	Gain
CMGC_CDK_CRK7_CDK12_ST	P24928	POLR2A	Q9NYV4	CDK12	S1668	S1665P	1665	Missense	distal	-3	no	4.368	4.274	EPSD	ICGC	0.929	Down-regulation
CMGC_CDK_CRK7_CDK12_ST	P24928	POLR2A	Q9NYV4	CDK12	S1829	A1835T	1835	Missense	distal	6	no	4.173	4.174	EPSD	ICGC	0.929	Up-regulation
CMGC_CDK_CRK7_CDK12_ST	P24928	POLR2A	Q9NYV4	CDK12	S1833	A1835T	1835	Missense	proximal	2	no	4.247	4.228	EPSD	ICGC	0.929	Down-regulation
CMGC_CDK_CRK7_CDK12_ST	P24928	POLR2A	Q9NYV4	CDK12	S1836	A1835T	1835	Missense	proximal	-1	no	4.238	4.248	EPSD	ICGC	0.929	Up-regulation
CMGC_CDK_CRK7_CDK12_ST	P24928	POLR2A	Q9NYV4	CDK12	T1840	A1835T	1835	Missense	distal	-5	no	4.803	4.792	EPSD	ICGC	0.929	Down-regulation
CMGC_CDK_CRK7_CDK12_ST	P24928	POLR2A	Q9NYV4	CDK12	S1843	S1850C	1850	Missense	distal	7	no	4.420	4.418	EPSD	ICGC	0.929	Down-regulation
CMGC_CDK_CRK7_CDK12_ST	P24928	POLR2A	Q9NYV4	CDK12	S1847	S1850C	1850	Missense	distal	3	no	4.644	4.632	EPSD	ICGC	0.929	Down-regulation
CMGC_CDK_CRK7_CDK12_ST	P24928	POLR2A	Q9NYV4	CDK12	S1847	T1854P	1854	Missense	distal	7	no	4.644	4.786	EPSD	ICGC	0.929	Up-regulation
CMGC_CDK_CRK7_CDK12_ST	P24928	POLR2A	Q9NYV4	CDK12	S1850	S1850C	1850	Missense	central	0	yes	3.936	0.000	EPSD	ICGC	0.929	Loss
CMGC_CDK_CRK7_CDK12_ST	P24928	POLR2A	Q9NYV4	CDK12	S1850	T1854P	1854	Missense	distal	4	no	3.936	4.442	EPSD	ICGC	0.929	Up-regulation
CMGC_CDK_CRK7_CDK12_ST	P24928	POLR2A	Q9NYV4	CDK12	T1854	S1861L	1861	Missense	distal	7	no	4.352	4.306	EPSD	ICGC	0.929	Down-regulation
CMGC_CDK_CRK7_CDK12_ST	P24928	POLR2A	Q9NYV4	CDK12	T1854	S1850C	1850	Missense	distal	-4	no	4.352	4.272	EPSD	ICGC	0.929	Down-regulation
CMGC_CDK_CRK7_CDK12_ST	P24928	POLR2A	Q9NYV4	CDK12	T1854	T1854P	1854	Missense	central	0	yes	4.352	0.000	EPSD	ICGC	0.929	Loss
CMGC_CDK_CRK7_CDK12_ST	P24928	POLR2A	Q9NYV4	CDK12	S1857	S1861L	1861	Missense	distal	4	no	4.546	4.252	EPSD	ICGC	0.929	Down-regulation
CMGC_CDK_CRK7_CDK12_ST	P24928	POLR2A	Q9NYV4	CDK12	S1857	S1850C	1850	Missense	distal	-7	no	4.546	4.463	EPSD	ICGC	0.929	Down-regulation
CMGC_CDK_CRK7_CDK12_ST	P24928	POLR2A	Q9NYV4	CDK12	S1857	T1854P	1854	Missense	distal	-3	no	4.546	4.450	EPSD	ICGC	0.929	Down-regulation
CMGC_CDK_CRK7_CDK12_ST	P24928	POLR2A	Q9NYV4	CDK12	S1861	S1861L	1861	Missense	central	0	yes	4.330	0.000	EPSD	ICGC	0.929	Loss
CMGC_CDK_CRK7_CDK12_ST	P24928	POLR2A	Q9NYV4	CDK12	S1861	T1854P	1854	Missense	distal	-7	no	4.330	4.307	EPSD	ICGC	0.929	Down-regulation
CMGC_CDK_CRK7_CDK12_ST	P24928	POLR2A	Q9NYV4	CDK12	S1864	S1861L	1861	Missense	distal	-3	no	3.958	3.916	EPSD	ICGC	0.929	Down-regulation
CMGC_CDK_CRK7_CDK12_ST	P24928	POLR2A	Q9NYV4	CDK12	S1868	S1861L	1861	Missense	distal	-7	no	4.193	4.079	EPSD	ICGC	0.929	Down-regulation
CMGC_CDK_CRK7_CDK12_ST	P24928	POLR2A	Q9NYV4	CDK12	T1885	P1890S	1890	Missense	distal	5	no	4.067	4.110	EPSD	ICGC	0.929	Up-regulation
CMGC_CDK_CRK7_CDK12_ST	P24928	POLR2A	Q9NYV4	CDK12	S1889	P1890S	1890	Missense	proximal	1	no	4.401	0.132	EPSD	ICGC	0.929	Loss
CMGC_CDK_CRK7_CDK12_ST	P24928	POLR2A	Q9NYV4	CDK12	S1892	P1890S	1890	Missense	proximal	-2	no	4.097	4.112	EPSD	ICGC	0.929	Up-regulation
CMGC_CDK_CRK7_CDK12_ST	P24928	POLR2A	Q9NYV4	CDK12	S1896	P1890S	1890	Missense	distal	-6	no	4.174	4.152	EPSD	ICGC	0.929	Down-regulation
CMGC_CDK_CRK7_CDK12_ST	P24928	POLR2A	Q9NYV4	CDK12	S1913	S1920F	1920	Missense	distal	7	no	3.778	3.762	EPSD	ICGC	0.929	Down-regulation
CMGC_CDK_CRK7_CDK12_ST	P24928	POLR2A	Q9NYV4	CDK12	S1917	S1920F	1920	Missense	distal	3	no	4.181	4.169	EPSD	ICGC	0.929	Down-regulation
CMGC_CDK_CRK7_CDK12_ST	P24928	POLR2A	Q9NYV4	CDK12	S1917	P1921H	1921	Missense	distal	4	no	4.181	3.602	EPSD	ICGC	0.929	Down-regulation
CMGC_CDK_CRK7_CDK12_ST	P24928	POLR2A	Q9NYV4	CDK12	S1920	S1927I	1927	Missense	distal	7	no	4.129	4.118	EPSD	ICGC	0.929	Down-regulation
CMGC_CDK_CRK7_CDK12_ST	P24928	POLR2A	Q9NYV4	CDK12	S1920	S1920F	1920	Missense	central	0	yes	4.129	0.000	EPSD	ICGC	0.929	Loss
CMGC_CDK_CRK7_CDK12_ST	P24928	POLR2A	Q9NYV4	CDK12	S1920	P1921H	1921	Missense	proximal	1	no	4.129	-0.040	EPSD	ICGC	0.929	Loss
CMGC_CDK_CRK7_CDK12_ST	P24928	POLR2A	Q9NYV4	CDK12	S1924	S1927I	1927	Missense	distal	3	no	4.485	4.471	EPSD	ICGC	0.929	Down-regulation
CMGC_CDK_CRK7_CDK12_ST	P24928	POLR2A	Q9NYV4	CDK12	S1924	S1920F	1920	Missense	distal	-4	no	4.485	4.378	EPSD	ICGC	0.929	Down-regulation
CMGC_CDK_CRK7_CDK12_ST	P24928	POLR2A	Q9NYV4	CDK12	S1924	P1921H	1921	Missense	distal	-3	no	4.485	4.554	EPSD	ICGC	0.929	Up-regulation
CMGC_CDK_CRK7_CDK12_ST	P24928	POLR2A	Q9NYV4	CDK12	S1927	S1927I	1927	Missense	central	0	yes	4.242	0.000	EPSD	ICGC	0.929	Loss
CMGC_CDK_CRK7_CDK12_ST	P24928	POLR2A	Q9NYV4	CDK12	S1927	S1920F	1920	Missense	distal	-7	no	4.242	4.151	EPSD	ICGC	0.929	Down-regulation
CMGC_CDK_CRK7_CDK12_ST	P24928	POLR2A	Q9NYV4	CDK12	S1927	P1921H	1921	Missense	distal	-6	no	4.242	4.217	EPSD	ICGC	0.929	Down-regulation
CMGC_CDK_CRK7_CDK12_ST	P24928	POLR2A	Q9NYV4	CDK12	S1931	S1927I	1927	Missense	distal	-4	no	4.437	4.282	EPSD	ICGC	0.929	Down-regulation
CMGC_CDK_CRK7_CDK12_ST	P24928	POLR2A	Q9NYV4	CDK12	S1931	S1938P	1938	Missense	distal	7	no	4.437	4.585	EPSD	ICGC	0.929	Up-regulation
CMGC_CDK_CRK7_CDK12_ST	P24928	POLR2A	Q9NYV4	CDK12	S1934	S1927I	1927	Missense	distal	-7	no	4.022	3.921	EPSD	ICGC	0.929	Down-regulation
CMGC_CDK_CRK7_CDK12_ST	P24928	POLR2A	Q9NYV4	CDK12	S1934	S1938P	1938	Missense	distal	4	no	4.022	4.468	EPSD	ICGC	0.929	Up-regulation
CMGC_CDK_CRK7_CDK12_ST	P24928	POLR2A	Q9NYV4	CDK12	S1941	S1938P	1938	Missense	distal	-3	no	4.371	4.277	EPSD	ICGC	0.929	Down-regulation
CMGC_CDK_CRK7_CDK12_ST	P24928	POLR2A	Q9NYV4	CDK12	S1944	S1938P	1938	Missense	distal	-6	no	4.099	4.121	EPSD	ICGC	0.929	Up-regulation
CMGC_CDK_CRK7_CDK12_ST	P24928	POLR2A	Q9NYV4	CDK12	S1948	P1952H	1952	Missense	distal	4	no	5.150	4.571	EPSD	ICGC	0.929	Down-regulation
CMGC_CDK_CRK7_CDK12_ST	P24928	POLR2A	Q9NYV4	CDK12	S1951	P1952H	1952	Missense	proximal	1	no	4.615	0.446	EPSD	ICGC	0.929	Loss
CMGC_CDK_CRK7_CDK12_ST	P24928	POLR2A	Q9NYV4	CDK12	S1958	P1963L	1963	Missense	distal	5	no	4.711	4.737	EPSD	ICGC	0.929	Up-regulation
CMGC_CDK_CRK7_CDK12_ST	P24928	POLR2A	Q9NYV4	CDK12	S1958	P1952H	1952	Missense	distal	-6	no	4.711	4.687	EPSD	ICGC	0.929	Down-regulation
CMGC_CDK_CRK7_CDK12_ST	P24928	POLR2A	Q9NYV4	CDK12	S1962	P1963L	1963	Missense	proximal	1	no	4.400	-0.481	EPSD	ICGC	0.929	Loss
CAMK_CAMK1_CAMK4_ST	P16220	CREB1	Q16566	CAMK4	S133	D140A	140	Missense	distal	7	no	14.892	16.519	PhosphoSitePlus	ICGC;COSMIC	9.847	Up-regulation
CAMK_CAMK1_CAMK4_ST	P16220	CREB1	Q16566	CAMK4	S143	D140A	140	Missense	distal	-3	no	12.079	11.328	EPSD	ICGC;COSMIC	9.847	Down-regulation
CAMK_CAMK1_CAMK4_ST	P14866	HNRNPL	Q16566	CAMK4	S29	A36T	36	Missense	distal	7	no	13.658	12.284	EPSD	ICGC;COSMIC	9.847	Down-regulation
CAMK_CAMK1_CAMK4_ST	P14866	HNRNPL	Q16566	CAMK4	S29	R26W	26	Missense	distal	-3	no	13.658	7.006	EPSD	ICGC	9.847	Loss
CAMK_CAMK1_CAMK4_ST	P14866	HNRNPL	Q16566	CAMK4	T63	H70N	70	Missense	distal	7	no	8.649	10.215	EPSD	ICGC	9.847	Gain
CAMK_CAMK1_CAMK4_ST	Q99623	PHB2	Q16566	CAMK4	T169	A172S	172	Missense	distal	3	no	14.945	15.064	EPSD	ICGC;COSMIC	9.847	Up-regulation
CAMK_CAMK1_CAMK4_ST	Q99623	PHB2	Q16566	CAMK4	S176	A172S	172	Missense	distal	-4	no	12.550	12.549	EPSD	ICGC;COSMIC	9.847	Down-regulation
CAMK_CAMK1_CAMK4_ST	Q9UQM7	CAMK2A	Q16566	CAMK4	T286	Q284K	284	Missense	proximal	-2	no	10.649	11.504	EPSD	ICGC	9.847	Up-regulation
CAMK_CAMK1_CAMK4_ST	Q9UQM7	CAMK2A	Q16566	CAMK4	T286	Q284H	284	Missense	proximal	-2	no	10.649	9.688	EPSD	ICGC;COSMIC	9.847	Loss
CAMK_CAMK1_CAMK4_ST	Q9UQM7	CAMK2A	Q16566	CAMK4	T286	L290Q	290	Missense	distal	4	no	10.649	9.937	EPSD	ICGC;COSMIC	9.847	Down-regulation
CAMK_CAMK1_CAMK4_ST	Q9UQM7	CAMK2A	Q16566	CAMK4	T286	T286I	286	Missense	central	0	yes	10.649	0.000	EPSD	ICGC;COSMIC	9.847	Loss
CAMK_CAMK1_CAMK4_ST	Q9UQM7	CAMK2A	Q16566	CAMK4	S314	G315R	315	Missense	proximal	1	no	12.919	13.026	EPSD	ICGC;COSMIC	9.847	Up-regulation
CAMK_CAMK1_CAMK4_ST	Q9UQM7	CAMK2A	Q16566	CAMK4	S314	R311M	311	Missense	distal	-3	no	12.919	6.923	EPSD	ICGC;COSMIC	9.847	Loss
CAMK_CAMK1_CAMK4_ST	Q9UQM7	CAMK2A	Q16566	CAMK4	S318	G315R	315	Missense	distal	-3	no	7.686	15.822	EPSD	ICGC;COSMIC	9.847	Gain
CAMK_CAMK1_CAMK4_ST	Q04206	RELA	Q16566	CAMK4	S45	G48S	48	Missense	distal	3	no	10.149	10.543	EPSD	ICGC;COSMIC	9.847	Up-regulation
CAMK_CAMK1_CAMK4_ST	Q04206	RELA	Q16566	CAMK4	S45	R41H	41	Missense	distal	-4	no	10.149	8.783	EPSD	ICGC;COSMIC	9.847	Loss
CAMK_CAMK1_CAMK4_ST	Q04206	RELA	Q16566	CAMK4	S131	R133C	133	Missense	proximal	2	no	10.188	10.230	EPSD	ICGC	9.847	Up-regulation
CAMK_CAMK1_CAMK4_ST	Q04206	RELA	Q16566	CAMK4	S131	D125E	125	Missense	distal	-6	no	10.188	10.142	EPSD	ICGC	9.847	Down-regulation
CAMK_CAMK1_CAMK4_ST	Q04206	RELA	Q16566	CAMK4	S131	E127Q	127	Missense	distal	-4	no	10.188	10.259	EPSD	ICGC;COSMIC	9.847	Up-regulation
CAMK_CAMK1_CAMK4_ST	Q04206	RELA	Q16566	CAMK4	S276	D277E	277	Missense	proximal	1	no	14.867	14.894	EPSD	ICGC;COSMIC	9.847	Up-regulation
CAMK_CAMK1_CAMK4_ST	Q04206	RELA	Q16566	CAMK4	S281	D277E	277	Missense	distal	-4	no	12.264	12.225	EPSD	ICGC;COSMIC	9.847	Down-regulation
CAMK_CAMK1_CAMK4_ST	Q04206	RELA	Q16566	CAMK4	T305	S311G	311	Missense	distal	6	no	10.192	9.895	EPSD	ICGC;COSMIC	9.847	Down-regulation
CAMK_CAMK1_CAMK4_ST	Q04206	RELA	Q16566	CAMK4	S337	R330H	330	Missense	distal	-7	no	11.395	8.963	EPSD	ICGC;COSMIC	9.847	Loss
CAMK_CAMK1_CAMK4_ST	Q04206	RELA	Q16566	CAMK4	S536	A538V	538	Missense	proximal	2	no	12.028	12.046	PhosphoSitePlus	ICGC;COSMIC	9.847	Up-regulation
CAMK_CAMK1_CAMK4_ST	Q04206	RELA	Q16566	CAMK4	S543	A538V	538	Missense	distal	-5	no	10.445	10.222	EPSD	ICGC;COSMIC	9.847	Down-regulation
CAMK_CAMK1_CAMK4_ST	Q04206	RELA	Q16566	CAMK4	S543	Q548P	548	Missense	distal	5	no	10.445	10.249	EPSD	ICGC;COSMIC	9.847	Down-regulation
CAMK_CAMK1_CAMK4_ST	P16949	STMN1	Q16566	CAMK4	S63	S63F	63	Missense	central	0	yes	14.468	0.000	EPSD	ICGC;COSMIC	9.847	Loss
CAMK_CAMKL_AMPK_PRKAA2_ST	Q13393	PLD1	P54646	PRKAA2	S505	R502L	502	Missense	distal	-3	no	70.246	59.290	PhosphoSitePlus	ICGC;COSMIC	46.832	Down-regulation
CAMK_CAMKL_AMPK_PRKAA2_ST	Q13393	PLD1	P54646	PRKAA2	S511	P514L	514	Missense	distal	3	no	53.367	55.023	EPSD	ICGC	46.832	Up-regulation
CAMK_CAMKL_AMPK_PRKAA2_ST	Q13393	PLD1	P54646	PRKAA2	S519	P514L	514	Missense	distal	-5	no	49.678	56.553	EPSD	ICGC	46.832	Up-regulation
CAMK_CAMKL_AMPK_PRKAA2_ST	Q13393	PLD1	P54646	PRKAA2	S519	S522F	522	Missense	distal	3	no	49.678	45.515	EPSD	ICGC;COSMIC	46.832	Loss
CAMK_CAMKL_AMPK_PRKAA2_ST	Q13393	PLD1	P54646	PRKAA2	S540	D545N	545	Missense	distal	5	no	47.072	47.041	EPSD	ICGC;COSMIC	46.832	Down-regulation
CAMK_CAMKL_AMPK_PRKAA2_ST	Q13393	PLD1	P54646	PRKAA2	S558	F557L	557	Missense	proximal	-1	no	52.395	53.010	EPSD	ICGC	46.832	Up-regulation
CAMK_CAMKL_AMPK_PRKAA2_ST	Q13393	PLD1	P54646	PRKAA2	S558	S558L	558	Missense	central	0	yes	52.395	0.000	EPSD	ICGC	46.832	Loss
CAMK_CAMKL_AMPK_PRKAA2_ST	Q13393	PLD1	P54646	PRKAA2	S558	K559R	559	Missense	proximal	1	no	52.395	52.316	EPSD	ICGC;COSMIC	46.832	Down-regulation
CAMK_CAMKL_AMPK_PRKAA2_ST	Q13393	PLD1	P54646	PRKAA2	S611	H608L	608	Missense	distal	-3	no	46.650	47.709	EPSD	ICGC;COSMIC	46.832	Gain
CAMK_CAMKL_AMPK_PRKAA2_ST	Q13393	PLD1	P54646	PRKAA2	S613	H608Q	608	Missense	distal	-5	no	36.572	46.929	EPSD	ICGC	46.832	Gain
CAMK_CAMKL_AMPK_PRKAA2_ST	Q13393	PLD1	P54646	PRKAA2	S613	H608L	608	Missense	distal	-5	no	36.572	60.360	EPSD	ICGC;COSMIC	46.832	Gain
CAMK_CAMKL_AMPK_PRKAA2_ST	Q9UQL6	HDAC5	P54646	PRKAA2	S225	S225R	225	Missense	central	0	yes	48.892	0.000	EPSD	ICGC;COSMIC	46.832	Loss
CAMK_CAMKL_AMPK_PRKAA2_ST	Q13085	ACACA	P54646	PRKAA2	S78	S78G	78	Missense	central	0	yes	49.939	0.000	EPSD	ICGC	46.832	Loss
CAMK_CAMKL_AMPK_PRKAA2_ST	Q13085	ACACA	P54646	PRKAA2	S78	S78I	78	Missense	central	0	yes	49.939	0.000	EPSD	ICGC	46.832	Loss
CAMK_CAMKL_AMPK_PRKAA2_ST	Q13085	ACACA	P54646	PRKAA2	S80	S78G	78	Missense	proximal	-2	no	67.645	65.221	PhosphoSitePlus	ICGC	46.832	Down-regulation
CAMK_CAMKL_AMPK_PRKAA2_ST	Q13085	ACACA	P54646	PRKAA2	S80	S78I	78	Missense	proximal	-2	no	67.645	63.646	PhosphoSitePlus	ICGC	46.832	Down-regulation
CAMK_CAMKL_AMPK_PRKAA2_ST	Q13085	ACACA	P54646	PRKAA2	T101	A103V	103	Missense	proximal	2	no	55.726	58.896	EPSD	ICGC	46.832	Up-regulation
CAMK_CAMKL_AMPK_PRKAA2_ST	Q13085	ACACA	P54646	PRKAA2	S344	F347L	347	Missense	distal	3	no	45.933	48.016	EPSD	ICGC	46.832	Gain
CAMK_CAMKL_AMPK_PRKAA2_ST	Q13085	ACACA	P54646	PRKAA2	S977	R980Q	980	Missense	distal	3	no	43.675	47.624	EPSD	ICGC;CCLE	46.832	Gain
CAMK_CAMKL_AMPK_PRKAA2_ST	Q13085	ACACA	P54646	PRKAA2	S1908	V1910L	1910	Missense	proximal	2	no	48.342	43.194	EPSD	ICGC	46.832	Loss
CAMK_CAMKL_AMPK_PRKAA2_ST	P09874	PARP1	P54646	PRKAA2	S25	S20F	20	Missense	distal	-5	no	47.150	49.625	EPSD	ICGC	46.832	Up-regulation
CAMK_CAMKL_AMPK_PRKAA2_ST	P09874	PARP1	P54646	PRKAA2	S25	K22R	22	Missense	distal	-3	no	47.150	52.600	EPSD	ICGC;COSMIC	46.832	Up-regulation
CAMK_CAMKL_AMPK_PRKAA2_ST	P09874	PARP1	P54646	PRKAA2	S25	R18S	18	Missense	distal	-7	no	47.150	47.431	EPSD	ICGC	46.832	Up-regulation
CAMK_CAMKL_AMPK_PRKAA2_ST	P09874	PARP1	P54646	PRKAA2	S120	G127W	127	Missense	distal	7	no	53.928	53.964	EPSD	ICGC	46.832	Up-regulation
CAMK_CAMKL_AMPK_PRKAA2_ST	P09874	PARP1	P54646	PRKAA2	S177	S177N	177	Missense	central	0	yes	72.801	0.000	PhosphoSitePlus	ICGC;COSMIC	46.832	Loss
CAMK_CAMKL_AMPK_PRKAA2_ST	P09874	PARP1	P54646	PRKAA2	S177	Q180H	180	Missense	distal	3	no	72.801	71.816	PhosphoSitePlus	ICGC;COSMIC	46.832	Down-regulation
CAMK_CAMKL_AMPK_PRKAA2_ST	P09874	PARP1	P54646	PRKAA2	T368	T368K	368	Missense	central	0	yes	47.400	0.000	EPSD	ICGC	46.832	Loss
CAMK_CAMKL_AMPK_PRKAA2_ST	P09874	PARP1	P54646	PRKAA2	S372	T368K	368	Missense	distal	-4	no	49.979	50.579	EPSD	ICGC	46.832	Up-regulation
CAMK_CAMKL_AMPK_PRKAA2_ST	P09874	PARP1	P54646	PRKAA2	T373	T368K	368	Missense	distal	-5	no	49.281	37.017	EPSD	ICGC	46.832	Loss
CAMK_CAMKL_AMPK_PRKAA2_ST	P09874	PARP1	P54646	PRKAA2	S375	T368K	368	Missense	distal	-7	no	48.725	48.804	EPSD	ICGC	46.832	Up-regulation
CAMK_CAMKL_AMPK_PRKAA2_ST	P09874	PARP1	P54646	PRKAA2	S455	D461G	461	Missense	distal	6	no	53.514	53.668	EPSD	ICGC;COSMIC	46.832	Up-regulation
CAMK_CAMKL_AMPK_PRKAA2_ST	P09874	PARP1	P54646	PRKAA2	S499	A502V	502	Missense	distal	3	no	58.269	53.201	EPSD	ICGC;COSMIC;GDSC	46.832	Down-regulation
CAMK_CAMKL_AMPK_PRKAA2_ST	P09874	PARP1	P54646	PRKAA2	S499	G500W	500	Missense	proximal	1	no	58.269	58.271	EPSD	ICGC;COSMIC	46.832	Up-regulation
CAMK_CAMKL_AMPK_PRKAA2_ST	P09874	PARP1	P54646	PRKAA2	S606	Q603K	603	Missense	distal	-3	no	39.035	47.850	EPSD	ICGC	46.832	Gain
CAMK_CAMKL_AMPK_PRKAA2_ST	P09874	PARP1	P54646	PRKAA2	T738	H742N	742	Missense	distal	4	no	27.168	47.618	EPSD	ICGC	46.832	Gain
CAMK_CAMKL_AMPK_PRKAA2_ST	O00418	EEF2K	P54646	PRKAA2	S48	T43M	43	Missense	distal	-5	no	46.373	48.727	EPSD	ICGC;COSMIC	46.832	Gain
CAMK_CAMKL_AMPK_PRKAA2_ST	O00418	EEF2K	P54646	PRKAA2	S345	K347N	347	Missense	proximal	2	no	43.560	49.925	EPSD	ICGC;COSMIC	46.832	Gain
CAMK_CAMKL_AMPK_PRKAA2_ST	O00418	EEF2K	P54646	PRKAA2	T364	R369W	369	Missense	distal	5	no	47.763	47.639	EPSD	ICGC	46.832	Down-regulation
CAMK_CAMKL_AMPK_PRKAA2_ST	O00418	EEF2K	P54646	PRKAA2	T364	Q361R	361	Missense	distal	-3	no	47.763	62.028	EPSD	ICGC	46.832	Up-regulation
CAMK_CAMKL_AMPK_PRKAA2_ST	O00418	EEF2K	P54646	PRKAA2	T364	P360L	360	Missense	distal	-4	no	47.763	46.030	EPSD	ICGC	46.832	Loss
CAMK_CAMKL_AMPK_PRKAA2_ST	O00418	EEF2K	P54646	PRKAA2	S398	S404C	404	Missense	distal	6	no	66.424	63.230	PhosphoSitePlus	ICGC	46.832	Down-regulation
CAMK_CAMKL_AMPK_PRKAA2_ST	P28562	DUSP1	P54646	PRKAA2	T141	L147I	147	Missense	distal	6	no	46.858	43.523	EPSD	ICGC	46.832	Loss
CAMK_CAMKL_AMPK_PRKAA2_ST	P28562	DUSP1	P54646	PRKAA2	T141	P142T	142	Missense	proximal	1	no	46.858	46.892	EPSD	ICGC;COSMIC	46.832	Up-regulation
CAMK_CAMKL_AMPK_PRKAA2_ST	P28562	DUSP1	P54646	PRKAA2	S334	D330E	330	Missense	distal	-4	no	71.466	70.113	PhosphoSitePlus	ICGC	46.832	Down-regulation
CAMK_CAMKL_AMPK_PRKAA2_ST	P28562	DUSP1	P54646	PRKAA2	S334	F341L	341	Missense	distal	7	no	71.466	69.971	PhosphoSitePlus	ICGC;COSMIC	46.832	Down-regulation
CAMK_CAMKL_AMPK_PRKAA2_ST	P28562	DUSP1	P54646	PRKAA2	S334	N340K	340	Missense	distal	6	no	71.466	70.606	PhosphoSitePlus	ICGC;COSMIC	46.832	Down-regulation
CAMK_CAMKL_AMPK_PRKAA2_ST	P30260	CDC27	P54646	PRKAA2	S222	L215W	215	Missense	distal	-7	no	49.547	49.366	EPSD	ICGC;COSMIC	46.832	Down-regulation
CAMK_CAMKL_AMPK_PRKAA2_ST	P30260	CDC27	P54646	PRKAA2	S233	I235T	235	Missense	proximal	2	no	58.460	52.334	EPSD	ICGC;COSMIC	46.832	Down-regulation
CAMK_CAMKL_AMPK_PRKAA2_ST	P30260	CDC27	P54646	PRKAA2	S233	Y234S	234	Missense	proximal	1	no	58.460	58.708	EPSD	ICGC;COSMIC	46.832	Up-regulation
CAMK_CAMKL_AMPK_PRKAA2_ST	P30260	CDC27	P54646	PRKAA2	S233	S231P	231	Missense	proximal	-2	no	58.460	59.031	EPSD	ICGC;COSMIC	46.832	Up-regulation
CAMK_CAMKL_AMPK_PRKAA2_ST	P30260	CDC27	P54646	PRKAA2	S233	S230Y	230	Missense	distal	-3	no	58.460	53.583	EPSD	ICGC;COSMIC	46.832	Down-regulation
CAMK_CAMKL_AMPK_PRKAA2_ST	P30260	CDC27	P54646	PRKAA2	S237	Y234S	234	Missense	distal	-3	no	45.447	50.324	EPSD	ICGC;COSMIC	46.832	Gain
CAMK_CAMKL_AMPK_PRKAA2_ST	P30260	CDC27	P54646	PRKAA2	T279	A273G	273	Missense	distal	-6	no	51.368	51.461	EPSD	ICGC;COSMIC	46.832	Up-regulation
CAMK_CAMKL_AMPK_PRKAA2_ST	P30260	CDC27	P54646	PRKAA2	T279	L275V	275	Missense	distal	-4	no	51.368	52.132	EPSD	ICGC;COSMIC	46.832	Up-regulation
CAMK_CAMKL_AMPK_PRKAA2_ST	P30260	CDC27	P54646	PRKAA2	T279	A274D	274	Missense	distal	-5	no	51.368	43.141	EPSD	ICGC;COSMIC	46.832	Loss
CAMK_CAMKL_AMPK_PRKAA2_ST	P30260	CDC27	P54646	PRKAA2	T279	L278F	278	Missense	proximal	-1	no	51.368	50.754	EPSD	ICGC;COSMIC	46.832	Down-regulation
CAMK_CAMKL_AMPK_PRKAA2_ST	P30260	CDC27	P54646	PRKAA2	T279	A274S	274	Missense	distal	-5	no	51.368	48.961	EPSD	ICGC;COSMIC	46.832	Down-regulation
CAMK_CAMKL_AMPK_PRKAA2_ST	P30260	CDC27	P54646	PRKAA2	T279	P286Q	286	Missense	distal	7	no	51.368	49.294	EPSD	ICGC;COSMIC	46.832	Down-regulation
CAMK_CAMKL_AMPK_PRKAA2_ST	P30260	CDC27	P54646	PRKAA2	T279	G283W	283	Missense	distal	4	no	51.368	41.557	EPSD	ICGC;COSMIC	46.832	Loss
CAMK_CAMKL_AMPK_PRKAA2_ST	P30260	CDC27	P54646	PRKAA2	T279	F282S	282	Missense	distal	3	no	51.368	55.531	EPSD	ICGC;COSMIC	46.832	Up-regulation
CAMK_CAMKL_AMPK_PRKAA2_ST	P30260	CDC27	P54646	PRKAA2	S296	T289A	289	Missense	distal	-7	no	47.929	47.871	EPSD	ICGC;COSMIC	46.832	Down-regulation
CAMK_CAMKL_AMPK_PRKAA2_ST	P30260	CDC27	P54646	PRKAA2	T313	A315T	315	Missense	proximal	2	no	51.952	48.245	EPSD	ICGC	46.832	Down-regulation
CAMK_CAMKL_AMPK_PRKAA2_ST	P30260	CDC27	P54646	PRKAA2	T313	G314R	314	Missense	proximal	1	no	51.952	51.877	EPSD	ICGC;COSMIC	46.832	Down-regulation
CAMK_CAMKL_AMPK_PRKAA2_ST	P30260	CDC27	P54646	PRKAA2	T313	P306S	306	Missense	distal	-7	no	51.952	52.097	EPSD	ICGC;COSMIC	46.832	Up-regulation
CAMK_CAMKL_AMPK_PRKAA2_ST	P30260	CDC27	P54646	PRKAA2	T313	S320P	320	Missense	distal	7	no	51.952	54.101	EPSD	ICGC;COSMIC	46.832	Up-regulation
CAMK_CAMKL_AMPK_PRKAA2_ST	P30260	CDC27	P54646	PRKAA2	T313	S320F	320	Missense	distal	7	no	51.952	53.868	EPSD	ICGC;COSMIC	46.832	Up-regulation
CAMK_CAMKL_AMPK_PRKAA2_ST	P30260	CDC27	P54646	PRKAA2	T313	V307E	307	Missense	distal	-6	no	51.952	52.655	EPSD	ICGC;COSMIC	46.832	Up-regulation
CAMK_CAMKL_AMPK_PRKAA2_ST	P30260	CDC27	P54646	PRKAA2	T313	P316H	316	Missense	distal	3	no	51.952	53.885	EPSD	ICGC;COSMIC	46.832	Up-regulation
CAMK_CAMKL_AMPK_PRKAA2_ST	P30260	CDC27	P54646	PRKAA2	S320	A315T	315	Missense	distal	-5	no	61.039	61.642	EPSD	ICGC	46.832	Up-regulation
CAMK_CAMKL_AMPK_PRKAA2_ST	P30260	CDC27	P54646	PRKAA2	S320	G314R	314	Missense	distal	-6	no	61.039	61.199	EPSD	ICGC;COSMIC	46.832	Up-regulation
CAMK_CAMKL_AMPK_PRKAA2_ST	P30260	CDC27	P54646	PRKAA2	S320	S320P	320	Missense	central	0	yes	61.039	0.000	EPSD	ICGC;COSMIC	46.832	Loss
CAMK_CAMKL_AMPK_PRKAA2_ST	P30260	CDC27	P54646	PRKAA2	S320	S320F	320	Missense	central	0	yes	61.039	0.000	EPSD	ICGC;COSMIC	46.832	Loss
CAMK_CAMKL_AMPK_PRKAA2_ST	P30260	CDC27	P54646	PRKAA2	S320	P316H	316	Missense	distal	-4	no	61.039	60.148	EPSD	ICGC;COSMIC	46.832	Down-regulation
CAMK_CAMKL_AMPK_PRKAA2_ST	P30260	CDC27	P54646	PRKAA2	S334	S336R	336	Missense	proximal	2	no	57.850	54.723	EPSD	ICGC;COSMIC	46.832	Down-regulation
CAMK_CAMKL_AMPK_PRKAA2_ST	P30260	CDC27	P54646	PRKAA2	S334	N338K	338	Missense	distal	4	no	57.850	43.873	EPSD	ICGC;COSMIC	46.832	Loss
CAMK_CAMKL_AMPK_PRKAA2_ST	P30260	CDC27	P54646	PRKAA2	S334	K330T	330	Missense	distal	-4	no	57.850	57.250	EPSD	ICGC;COSMIC	46.832	Down-regulation
CAMK_CAMKL_AMPK_PRKAA2_ST	P30260	CDC27	P54646	PRKAA2	S334	T329K	329	Missense	distal	-5	no	57.850	45.586	EPSD	ICGC	46.832	Loss
CAMK_CAMKL_AMPK_PRKAA2_ST	P30260	CDC27	P54646	PRKAA2	S334	N338S	338	Missense	distal	4	no	57.850	61.525	EPSD	ICGC;COSMIC	46.832	Up-regulation
CAMK_CAMKL_AMPK_PRKAA2_ST	P30260	CDC27	P54646	PRKAA2	T349	I345V	345	Missense	distal	-4	no	50.899	51.647	EPSD	ICGC;COSMIC	46.832	Up-regulation
CAMK_CAMKL_AMPK_PRKAA2_ST	P30260	CDC27	P54646	PRKAA2	T349	L346I	346	Missense	distal	-3	no	50.899	48.884	EPSD	ICGC;COSMIC	46.832	Down-regulation
CAMK_CAMKL_AMPK_PRKAA2_ST	P30260	CDC27	P54646	PRKAA2	T349	L346F	346	Missense	distal	-3	no	50.899	49.648	EPSD	ICGC;COSMIC	46.832	Down-regulation
CAMK_CAMKL_AMPK_PRKAA2_ST	P30260	CDC27	P54646	PRKAA2	T349	Q348K	348	Missense	proximal	-1	no	50.899	50.782	EPSD	ICGC;COSMIC	46.832	Down-regulation
CAMK_CAMKL_AMPK_PRKAA2_ST	P30260	CDC27	P54646	PRKAA2	T349	T356I	356	Missense	distal	7	no	50.899	51.131	EPSD	ICGC;COSMIC	46.832	Up-regulation
CAMK_CAMKL_AMPK_PRKAA2_ST	P30260	CDC27	P54646	PRKAA2	T349	T356A	356	Missense	distal	7	no	50.899	50.343	EPSD	ICGC;COSMIC	46.832	Down-regulation
CAMK_CAMKL_AMPK_PRKAA2_ST	P30260	CDC27	P54646	PRKAA2	T358	Q361H	361	Missense	distal	3	no	54.049	53.064	EPSD	ICGC;COSMIC	46.832	Down-regulation
CAMK_CAMKL_AMPK_PRKAA2_ST	P30260	CDC27	P54646	PRKAA2	T358	T356I	356	Missense	proximal	-2	no	54.049	53.024	EPSD	ICGC;COSMIC	46.832	Down-regulation
CAMK_CAMKL_AMPK_PRKAA2_ST	P30260	CDC27	P54646	PRKAA2	T358	P360H	360	Missense	proximal	2	no	54.049	42.264	EPSD	ICGC;COSMIC	46.832	Loss
CAMK_CAMKL_AMPK_PRKAA2_ST	P30260	CDC27	P54646	PRKAA2	T358	V362I	362	Missense	distal	4	no	54.049	55.362	EPSD	ICGC;COSMIC	46.832	Up-regulation
CAMK_CAMKL_AMPK_PRKAA2_ST	P30260	CDC27	P54646	PRKAA2	T358	Q361E	361	Missense	distal	3	no	54.049	52.168	EPSD	ICGC;COSMIC	46.832	Down-regulation
CAMK_CAMKL_AMPK_PRKAA2_ST	P30260	CDC27	P54646	PRKAA2	T358	T356A	356	Missense	proximal	-2	no	54.049	55.265	EPSD	ICGC;COSMIC	46.832	Up-regulation
CAMK_CAMKL_AMPK_PRKAA2_ST	P30260	CDC27	P54646	PRKAA2	S369	R376Q	376	Missense	distal	7	no	47.841	46.989	EPSD	ICGC;COSMIC	46.832	Down-regulation
CAMK_CAMKL_AMPK_PRKAA2_ST	P30260	CDC27	P54646	PRKAA2	S369	I367M	367	Missense	proximal	-2	no	47.841	47.882	EPSD	ICGC;COSMIC	46.832	Up-regulation
CAMK_CAMKL_AMPK_PRKAA2_ST	P30260	CDC27	P54646	PRKAA2	S369	P375H	375	Missense	distal	6	no	47.841	48.561	EPSD	ICGC	46.832	Up-regulation
CAMK_CAMKL_AMPK_PRKAA2_ST	P30260	CDC27	P54646	PRKAA2	S369	T368I	368	Missense	proximal	-1	no	47.841	47.536	EPSD	ICGC	46.832	Down-regulation
CAMK_CAMKL_AMPK_PRKAA2_ST	P30260	CDC27	P54646	PRKAA2	S369	A373T	373	Missense	distal	4	no	47.841	54.104	EPSD	ICGC;COSMIC;CCLE	46.832	Up-regulation
CAMK_CAMKL_AMPK_PRKAA2_ST	P30260	CDC27	P54646	PRKAA2	S369	V362I	362	Missense	distal	-7	no	47.841	47.480	EPSD	ICGC;COSMIC	46.832	Down-regulation
CAMK_CAMKL_AMPK_PRKAA2_ST	P30260	CDC27	P54646	PRKAA2	S379	R376Q	376	Missense	distal	-3	no	64.169	49.904	PhosphoSitePlus	ICGC;COSMIC	46.832	Down-regulation
CAMK_CAMKL_AMPK_PRKAA2_ST	P30260	CDC27	P54646	PRKAA2	S379	F382L	382	Missense	distal	3	no	64.169	66.251	PhosphoSitePlus	ICGC;COSMIC	46.832	Up-regulation
CAMK_CAMKL_AMPK_PRKAA2_ST	P30260	CDC27	P54646	PRKAA2	S379	P375H	375	Missense	distal	-4	no	64.169	63.277	PhosphoSitePlus	ICGC	46.832	Down-regulation
CAMK_CAMKL_AMPK_PRKAA2_ST	P30260	CDC27	P54646	PRKAA2	S379	S384G	384	Missense	distal	5	no	64.169	64.151	PhosphoSitePlus	ICGC;COSMIC	46.832	Down-regulation
CAMK_CAMKL_AMPK_PRKAA2_ST	P30260	CDC27	P54646	PRKAA2	S379	S379L	379	Missense	central	0	yes	64.169	0.000	PhosphoSitePlus	ICGC;COSMIC	46.832	Loss
CAMK_CAMKL_AMPK_PRKAA2_ST	P30260	CDC27	P54646	PRKAA2	S379	S384N	384	Missense	distal	5	no	64.169	64.168	PhosphoSitePlus	ICGC;COSMIC	46.832	Down-regulation
CAMK_CAMKL_AMPK_PRKAA2_ST	P30260	CDC27	P54646	PRKAA2	S379	A373T	373	Missense	distal	-6	no	64.169	65.010	PhosphoSitePlus	ICGC;COSMIC;CCLE	46.832	Up-regulation
CAMK_CAMKL_AMPK_PRKAA2_ST	P30260	CDC27	P54646	PRKAA2	T383	S387Y	387	Missense	distal	4	no	50.736	28.772	EPSD	ICGC;COSMIC	46.832	Loss
CAMK_CAMKL_AMPK_PRKAA2_ST	P30260	CDC27	P54646	PRKAA2	T383	R376Q	376	Missense	distal	-7	no	50.736	50.585	EPSD	ICGC;COSMIC	46.832	Down-regulation
CAMK_CAMKL_AMPK_PRKAA2_ST	P30260	CDC27	P54646	PRKAA2	T383	T389N	389	Missense	distal	6	no	50.736	52.354	EPSD	ICGC;COSMIC	46.832	Up-regulation
CAMK_CAMKL_AMPK_PRKAA2_ST	P30260	CDC27	P54646	PRKAA2	T383	K390E	390	Missense	distal	7	no	50.736	51.046	EPSD	ICGC;COSMIC	46.832	Up-regulation
CAMK_CAMKL_AMPK_PRKAA2_ST	P30260	CDC27	P54646	PRKAA2	T383	F382L	382	Missense	proximal	-1	no	50.736	51.351	EPSD	ICGC;COSMIC	46.832	Up-regulation
CAMK_CAMKL_AMPK_PRKAA2_ST	P30260	CDC27	P54646	PRKAA2	T383	S384G	384	Missense	proximal	1	no	50.736	50.611	EPSD	ICGC;COSMIC	46.832	Down-regulation
CAMK_CAMKL_AMPK_PRKAA2_ST	P30260	CDC27	P54646	PRKAA2	T383	S379L	379	Missense	distal	-4	no	50.736	49.025	EPSD	ICGC;COSMIC	46.832	Down-regulation
CAMK_CAMKL_AMPK_PRKAA2_ST	P30260	CDC27	P54646	PRKAA2	T383	S384N	384	Missense	proximal	1	no	50.736	50.625	EPSD	ICGC;COSMIC	46.832	Down-regulation
CAMK_CAMKL_AMPK_PRKAA2_ST	P30260	CDC27	P54646	PRKAA2	S384	S387Y	387	Missense	distal	3	no	53.314	47.529	EPSD	ICGC;COSMIC	46.832	Down-regulation
CAMK_CAMKL_AMPK_PRKAA2_ST	P30260	CDC27	P54646	PRKAA2	S384	T389N	389	Missense	distal	5	no	53.314	53.569	EPSD	ICGC;COSMIC	46.832	Up-regulation
CAMK_CAMKL_AMPK_PRKAA2_ST	P30260	CDC27	P54646	PRKAA2	S384	K390E	390	Missense	distal	6	no	53.314	52.755	EPSD	ICGC;COSMIC	46.832	Down-regulation
CAMK_CAMKL_AMPK_PRKAA2_ST	P30260	CDC27	P54646	PRKAA2	S384	F382L	382	Missense	proximal	-2	no	53.314	59.248	EPSD	ICGC;COSMIC	46.832	Up-regulation
CAMK_CAMKL_AMPK_PRKAA2_ST	P30260	CDC27	P54646	PRKAA2	S384	S384G	384	Missense	central	0	yes	53.314	0.000	EPSD	ICGC;COSMIC	46.832	Loss
CAMK_CAMKL_AMPK_PRKAA2_ST	P30260	CDC27	P54646	PRKAA2	S384	S379L	379	Missense	distal	-5	no	53.314	57.805	EPSD	ICGC;COSMIC	46.832	Up-regulation
CAMK_CAMKL_AMPK_PRKAA2_ST	P30260	CDC27	P54646	PRKAA2	S384	S384N	384	Missense	central	0	yes	53.314	0.000	EPSD	ICGC;COSMIC	46.832	Loss
CAMK_CAMKL_AMPK_PRKAA2_ST	P30260	CDC27	P54646	PRKAA2	S435	S435F	435	Missense	central	0	yes	48.758	0.000	EPSD	ICGC;COSMIC	46.832	Loss
CAMK_CAMKL_AMPK_PRKAA2_ST	P30260	CDC27	P54646	PRKAA2	S435	G440E	440	Missense	distal	5	no	48.758	48.480	EPSD	ICGC;COSMIC	46.832	Down-regulation
CAMK_CAMKL_AMPK_PRKAA2_ST	P30260	CDC27	P54646	PRKAA2	S435	K441E	441	Missense	distal	6	no	48.758	48.199	EPSD	ICGC	46.832	Down-regulation
CAMK_CAMKL_AMPK_PRKAA2_ST	P30260	CDC27	P54646	PRKAA2	S435	I429V	429	Missense	distal	-6	no	48.758	48.859	EPSD	ICGC;COSMIC	46.832	Up-regulation
CAMK_CAMKL_AMPK_PRKAA2_ST	P30260	CDC27	P54646	PRKAA2	S435	I429M	429	Missense	distal	-6	no	48.758	49.145	EPSD	ICGC;COSMIC	46.832	Up-regulation
CAMK_CAMKL_AMPK_PRKAA2_ST	P30260	CDC27	P54646	PRKAA2	S435	I436V	436	Missense	proximal	1	no	48.758	48.710	EPSD	ICGC;COSMIC	46.832	Down-regulation
CAMK_CAMKL_AMPK_PRKAA2_ST	P30260	CDC27	P54646	PRKAA2	S435	S434Y	434	Missense	proximal	-1	no	48.758	47.823	EPSD	ICGC;COSMIC	46.832	Down-regulation
CAMK_CAMKL_AMPK_PRKAA2_ST	O43524	FOXO3	P54646	PRKAA2	S7	P10T	10	Missense	distal	3	no	45.479	48.356	EPSD	ICGC;COSMIC	46.832	Gain
CAMK_CAMKL_AMPK_PRKAA2_ST	O43524	FOXO3	P54646	PRKAA2	S75	G80S	80	Missense	distal	5	no	48.531	48.549	EPSD	ICGC;COSMIC	46.832	Up-regulation
CAMK_CAMKL_AMPK_PRKAA2_ST	O43524	FOXO3	P54646	PRKAA2	T179	P174L	174	Missense	distal	-5	no	67.236	74.111	EPSD;PhosphoSitePlus	ICGC;COSMIC	46.832	Up-regulation
CAMK_CAMKL_AMPK_PRKAA2_ST	O43524	FOXO3	P54646	PRKAA2	T179	S172N	172	Missense	distal	-7	no	67.236	67.276	EPSD;PhosphoSitePlus	ICGC	46.832	Up-regulation
CAMK_CAMKL_AMPK_PRKAA2_ST	O43524	FOXO3	P54646	PRKAA2	T179	P174T	174	Missense	distal	-5	no	67.236	72.631	EPSD;PhosphoSitePlus	ICGC;COSMIC	46.832	Up-regulation
CAMK_CAMKL_AMPK_PRKAA2_ST	O43524	FOXO3	P54646	PRKAA2	T179	K176R	176	Missense	distal	-3	no	67.236	72.686	EPSD;PhosphoSitePlus	ICGC;COSMIC	46.832	Up-regulation
CAMK_CAMKL_AMPK_PRKAA2_ST	O43524	FOXO3	P54646	PRKAA2	S253	R249L	249	Missense	distal	-4	no	51.904	50.277	EPSD	ICGC;COSMIC	46.832	Down-regulation
CAMK_CAMKL_AMPK_PRKAA2_ST	O43524	FOXO3	P54646	PRKAA2	T313	A317T	317	Missense	distal	4	no	41.423	47.686	EPSD	ICGC;COSMIC	46.832	Gain
CAMK_CAMKL_AMPK_PRKAA2_ST	O43524	FOXO3	P54646	PRKAA2	S315	A317T	317	Missense	proximal	2	no	54.324	50.617	EPSD	ICGC;COSMIC	46.832	Down-regulation
CAMK_CAMKL_AMPK_PRKAA2_ST	O43524	FOXO3	P54646	PRKAA2	T319	A317T	317	Missense	proximal	-2	no	52.081	50.865	EPSD	ICGC;COSMIC	46.832	Down-regulation
CAMK_CAMKL_AMPK_PRKAA2_ST	O43524	FOXO3	P54646	PRKAA2	T395	D389N	389	Missense	distal	-6	no	47.132	47.339	EPSD	ICGC;COSMIC	46.832	Up-regulation
CAMK_CAMKL_AMPK_PRKAA2_ST	O43524	FOXO3	P54646	PRKAA2	T395	D392N	392	Missense	distal	-3	no	47.132	44.673	EPSD	ICGC;COSMIC	46.832	Loss
CAMK_CAMKL_AMPK_PRKAA2_ST	O43524	FOXO3	P54646	PRKAA2	T395	S399F	399	Missense	distal	4	no	47.132	50.650	EPSD	ICGC	46.832	Up-regulation
CAMK_CAMKL_AMPK_PRKAA2_ST	O43524	FOXO3	P54646	PRKAA2	S399	D392N	392	Missense	distal	-7	no	65.379	65.614	EPSD;PhosphoSitePlus	ICGC;COSMIC	46.832	Up-regulation
CAMK_CAMKL_AMPK_PRKAA2_ST	O43524	FOXO3	P54646	PRKAA2	S399	S399F	399	Missense	central	0	yes	65.379	0.000	EPSD;PhosphoSitePlus	ICGC	46.832	Loss
CAMK_CAMKL_AMPK_PRKAA2_ST	O43524	FOXO3	P54646	PRKAA2	S411	P415L	415	Missense	distal	4	no	40.582	48.916	EPSD	ICGC;COSMIC;GDSC	46.832	Gain
CAMK_CAMKL_AMPK_PRKAA2_ST	O43524	FOXO3	P54646	PRKAA2	S413	P415L	415	Missense	proximal	2	no	68.510	62.398	EPSD;PhosphoSitePlus	ICGC;COSMIC;GDSC	46.832	Down-regulation
CAMK_CAMKL_AMPK_PRKAA2_ST	O43524	FOXO3	P54646	PRKAA2	S413	G420S	420	Missense	distal	7	no	68.510	67.279	EPSD;PhosphoSitePlus	ICGC;COSMIC	46.832	Down-regulation
CAMK_CAMKL_AMPK_PRKAA2_ST	O43524	FOXO3	P54646	PRKAA2	S413	F414L	414	Missense	proximal	1	no	68.510	68.619	EPSD;PhosphoSitePlus	ICGC	46.832	Up-regulation
CAMK_CAMKL_AMPK_PRKAA2_ST	O43524	FOXO3	P54646	PRKAA2	S428	G424S	424	Missense	distal	-4	no	47.039	49.069	EPSD	ICGC;COSMIC	46.832	Up-regulation
CAMK_CAMKL_AMPK_PRKAA2_ST	O43524	FOXO3	P54646	PRKAA2	S428	S429Y	429	Missense	proximal	1	no	47.039	46.791	EPSD	ICGC;COSMIC	46.832	Loss
CAMK_CAMKL_AMPK_PRKAA2_ST	O43524	FOXO3	P54646	PRKAA2	S429	G424S	424	Missense	distal	-5	no	48.023	47.134	EPSD	ICGC;COSMIC	46.832	Down-regulation
CAMK_CAMKL_AMPK_PRKAA2_ST	O43524	FOXO3	P54646	PRKAA2	S429	S429Y	429	Missense	central	0	yes	48.023	0.000	EPSD	ICGC;COSMIC	46.832	Loss
CAMK_CAMKL_AMPK_PRKAA2_ST	O43524	FOXO3	P54646	PRKAA2	S432	S429Y	429	Missense	distal	-3	no	49.361	44.485	EPSD	ICGC;COSMIC	46.832	Loss
CAMK_CAMKL_AMPK_PRKAA2_ST	O43524	FOXO3	P54646	PRKAA2	S438	N441K	441	Missense	distal	3	no	48.550	45.533	EPSD	ICGC	46.832	Loss
CAMK_CAMKL_AMPK_PRKAA2_ST	O43524	FOXO3	P54646	PRKAA2	S438	S442F	442	Missense	distal	4	no	48.550	52.068	EPSD	ICGC;COSMIC	46.832	Up-regulation
CAMK_CAMKL_AMPK_PRKAA2_ST	O43524	FOXO3	P54646	PRKAA2	S439	N441K	441	Missense	proximal	2	no	54.748	48.384	EPSD	ICGC	46.832	Down-regulation
CAMK_CAMKL_AMPK_PRKAA2_ST	O43524	FOXO3	P54646	PRKAA2	S439	S442F	442	Missense	distal	3	no	54.748	50.585	EPSD	ICGC;COSMIC	46.832	Down-regulation
CAMK_CAMKL_AMPK_PRKAA2_ST	O43524	FOXO3	P54646	PRKAA2	S442	N441K	441	Missense	proximal	-1	no	52.593	52.055	EPSD	ICGC	46.832	Down-regulation
CAMK_CAMKL_AMPK_PRKAA2_ST	O43524	FOXO3	P54646	PRKAA2	S442	S442F	442	Missense	central	0	yes	52.593	0.000	EPSD	ICGC;COSMIC	46.832	Loss
CAMK_CAMKL_AMPK_PRKAA2_ST	O43524	FOXO3	P54646	PRKAA2	S446	N441K	441	Missense	distal	-5	no	49.138	38.977	EPSD	ICGC	46.832	Loss
CAMK_CAMKL_AMPK_PRKAA2_ST	O43524	FOXO3	P54646	PRKAA2	S446	S442F	442	Missense	distal	-4	no	49.138	47.902	EPSD	ICGC;COSMIC	46.832	Down-regulation
CAMK_CAMKL_AMPK_PRKAA2_ST	O43524	FOXO3	P54646	PRKAA2	S551	R548C	548	Missense	distal	-3	no	54.803	41.530	EPSD	ICGC;COSMIC	46.832	Loss
CAMK_CAMKL_AMPK_PRKAA2_ST	O43524	FOXO3	P54646	PRKAA2	S555	R548C	548	Missense	distal	-7	no	66.106	65.803	EPSD;PhosphoSitePlus	ICGC;COSMIC	46.832	Down-regulation
CAMK_CAMKL_AMPK_PRKAA2_ST	Q9BZL4	PPP1R12C	P54646	PRKAA2	T290	L289M	289	Missense	proximal	-1	no	51.675	51.209	EPSD	ICGC	46.832	Down-regulation
CAMK_CAMKL_AMPK_PRKAA2_ST	Q9BZL4	PPP1R12C	P54646	PRKAA2	T290	Q294K	294	Missense	distal	4	no	51.675	43.721	EPSD	ICGC	46.832	Loss
CAMK_CAMKL_AMPK_PRKAA2_ST	Q9BZL4	PPP1R12C	P54646	PRKAA2	T290	G283D	283	Missense	distal	-7	no	51.675	51.836	EPSD	ICGC	46.832	Up-regulation
CAMK_CAMKL_AMPK_PRKAA2_ST	Q9BZL4	PPP1R12C	P54646	PRKAA2	T290	G293W	293	Missense	distal	3	no	51.675	49.652	EPSD	ICGC;COSMIC	46.832	Down-regulation
CAMK_CAMKL_AMPK_PRKAA2_ST	Q9BZL4	PPP1R12C	P54646	PRKAA2	T290	A292V	292	Missense	proximal	2	no	51.675	54.844	EPSD	ICGC;COSMIC	46.832	Up-regulation
CAMK_CAMKL_AMPK_PRKAA2_ST	Q9BZL4	PPP1R12C	P54646	PRKAA2	S344	S349I	349	Missense	distal	5	no	55.060	54.875	EPSD	ICGC	46.832	Down-regulation
CAMK_CAMKL_AMPK_PRKAA2_ST	Q9BZL4	PPP1R12C	P54646	PRKAA2	S399	H402Q	402	Missense	distal	3	no	54.644	55.628	EPSD	ICGC	46.832	Up-regulation
CAMK_CAMKL_AMPK_PRKAA2_ST	Q9BZL4	PPP1R12C	P54646	PRKAA2	S452	L447M	447	Missense	distal	-5	no	70.646	71.520	PhosphoSitePlus	ICGC;COSMIC	46.832	Up-regulation
CAMK_CAMKL_AMPK_PRKAA2_ST	Q9BZL4	PPP1R12C	P54646	PRKAA2	S452	L456M	456	Missense	distal	4	no	70.646	65.260	PhosphoSitePlus	ICGC	46.832	Down-regulation
CAMK_CAMKL_AMPK_PRKAA2_ST	Q9BZL4	PPP1R12C	P54646	PRKAA2	S509	V515I	515	Missense	distal	6	no	55.078	56.045	EPSD	ICGC	46.832	Up-regulation
CAMK_CAMKL_AMPK_PRKAA2_ST	Q9BZL4	PPP1R12C	P54646	PRKAA2	S509	P510T	510	Missense	proximal	1	no	55.078	55.112	EPSD	ICGC;COSMIC	46.832	Up-regulation
CAMK_CAMKL_AMPK_PRKAA2_ST	Q9BZL4	PPP1R12C	P54646	PRKAA2	S559	T560I	560	Missense	proximal	1	no	49.854	49.748	EPSD	ICGC;COSMIC	46.832	Down-regulation
CAMK_CAMKL_AMPK_PRKAA2_ST	Q9BXM7	PINK1	P54646	PRKAA2	S284	A280T	280	Missense	distal	-4	no	70.151	70.422	EPSD;PhosphoSitePlus	ICGC;COSMIC	46.832	Up-regulation
CAMK_CAMKL_AMPK_PRKAA2_ST	Q9BXM7	PINK1	P54646	PRKAA2	S284	A291S	291	Missense	distal	7	no	70.151	69.474	EPSD;PhosphoSitePlus	ICGC;COSMIC	46.832	Down-regulation
CAMK_CAMKL_AMPK_PRKAA2_ST	Q9BXM7	PINK1	P54646	PRKAA2	S284	V285L	285	Missense	proximal	1	no	70.151	70.388	EPSD;PhosphoSitePlus	ICGC;COSMIC	46.832	Up-regulation
CAMK_CAMKL_AMPK_PRKAA2_ST	Q9BXM7	PINK1	P54646	PRKAA2	S495	P498Q	498	Missense	distal	3	no	68.340	71.258	EPSD;PhosphoSitePlus	ICGC;COSMIC	46.832	Up-regulation
CAMK_CAMKL_AMPK_PRKAA2_ST	Q92819	HAS2	P54646	PRKAA2	T110	P112S	112	Missense	proximal	2	no	64.631	62.461	PhosphoSitePlus	ICGC	46.832	Down-regulation
CAMK_CAMKL_AMPK_PRKAA2_ST	Q92819	HAS2	P54646	PRKAA2	S334	T338S	338	Missense	distal	4	no	50.856	49.203	EPSD	ICGC;COSMIC	46.832	Down-regulation
CAMK_CAMKL_AMPK_PRKAA2_ST	Q92819	HAS2	P54646	PRKAA2	S334	T328K	328	Missense	distal	-6	no	50.856	50.521	EPSD	ICGC	46.832	Down-regulation
CAMK_CAMKL_AMPK_PRKAA2_ST	Q92819	HAS2	P54646	PRKAA2	S334	T328P	328	Missense	distal	-6	no	50.856	50.049	EPSD	ICGC	46.832	Down-regulation
CAMK_CAMKL_AMPK_PRKAA2_ST	Q92819	HAS2	P54646	PRKAA2	S440	L442S	442	Missense	proximal	2	no	44.081	48.024	EPSD	ICGC	46.832	Gain
CAMK_CAMKL_AMPK_PRKAA2_ST	Q9UQB8	BAIAP2	P54646	PRKAA2	S452	T455M	455	Missense	distal	3	no	49.826	43.637	EPSD	ICGC;COSMIC	46.832	Loss
CAMK_CAMKL_AMPK_PRKAA2_ST	Q9UQB8	BAIAP2	P54646	PRKAA2	S452	G450W	450	Missense	proximal	-2	no	49.826	45.424	EPSD	ICGC;COSMIC	46.832	Loss
CAMK_CAMKL_AMPK_PRKAA2_ST	Q13177	PAK2	P54646	PRKAA2	S19	S20R	20	Missense	proximal	1	no	48.254	48.054	EPSD	ICGC;COSMIC	46.832	Down-regulation
CAMK_CAMKL_AMPK_PRKAA2_ST	Q13177	PAK2	P54646	PRKAA2	S19	T25A	25	Missense	distal	6	no	48.254	50.831	EPSD	ICGC	46.832	Up-regulation
CAMK_CAMKL_AMPK_PRKAA2_ST	Q13177	PAK2	P54646	PRKAA2	S20	S20R	20	Missense	central	0	yes	62.155	0.000	PhosphoSitePlus	ICGC;COSMIC	46.832	Loss
CAMK_CAMKL_AMPK_PRKAA2_ST	Q13177	PAK2	P54646	PRKAA2	S20	T25A	25	Missense	distal	5	no	62.155	62.432	PhosphoSitePlus	ICGC	46.832	Up-regulation
CAMK_CAMKL_AMPK_PRKAA2_ST	Q13177	PAK2	P54646	PRKAA2	T195	T190M	190	Missense	distal	-5	no	51.250	53.604	EPSD	ICGC;COSMIC	46.832	Up-regulation
CAMK_CAMKL_AMPK_PRKAA2_ST	Q13177	PAK2	P54646	PRKAA2	T195	H189Y	189	Missense	distal	-6	no	51.250	50.394	EPSD	ICGC	46.832	Down-regulation
CAMK_CAMKL_AMPK_PRKAA2_ST	Q13177	PAK2	P54646	PRKAA2	T238	P245T	245	Missense	distal	7	no	55.175	54.259	EPSD	ICGC;COSMIC	46.832	Down-regulation
CAMK_CAMKL_AMPK_PRKAA2_ST	Q13177	PAK2	P54646	PRKAA2	S398	Q392L	392	Missense	distal	-6	no	50.360	49.346	EPSD	ICGC;COSMIC	46.832	Down-regulation
CAMK_CAMKL_AMPK_PRKAA2_ST	Q13177	PAK2	P54646	PRKAA2	S398	Q392R	392	Missense	distal	-6	no	50.360	50.162	EPSD	ICGC;COSMIC	46.832	Down-regulation
CAMK_CAMKL_AMPK_PRKAA2_ST	P05549	TFAP2A	P54646	PRKAA2	S119	D126Y	126	Missense	distal	7	no	47.541	49.505	EPSD	ICGC	46.832	Up-regulation
CAMK_CAMKL_AMPK_PRKAA2_ST	P05549	TFAP2A	P54646	PRKAA2	S187	S185F	185	Missense	proximal	-2	no	56.740	50.430	EPSD	ICGC;COSMIC	46.832	Down-regulation
CAMK_CAMKL_AMPK_PRKAA2_ST	P05549	TFAP2A	P54646	PRKAA2	S187	S185C	185	Missense	proximal	-2	no	56.740	54.750	EPSD	ICGC;COSMIC	46.832	Down-regulation
CAMK_CAMKL_AMPK_PRKAA2_ST	P05549	TFAP2A	P54646	PRKAA2	S191	S185F	185	Missense	distal	-6	no	49.438	48.111	EPSD	ICGC;COSMIC	46.832	Down-regulation
CAMK_CAMKL_AMPK_PRKAA2_ST	P05549	TFAP2A	P54646	PRKAA2	S191	S185C	185	Missense	distal	-6	no	49.438	47.407	EPSD	ICGC;COSMIC	46.832	Down-regulation
AGC_NDR_NDR_STK38L_ST	O60285	NUAK1	Q9Y2H1	STK38L	T211	K205N	205	Missense	distal	-6	no	8.221	8.266	PhosphoSitePlus	ICGC;COSMIC	2.379	Up-regulation
AGC_NDR_NDR_STK38L_ST	O60285	NUAK1	Q9Y2H1	STK38L	S444	E449Q	449	Missense	distal	5	no	2.435	2.530	EPSD	ICGC;COSMIC	2.379	Up-regulation
AGC_NDR_NDR_STK38L_ST	O60285	NUAK1	Q9Y2H1	STK38L	S444	V440M	440	Missense	distal	-4	no	2.435	2.328	EPSD	ICGC	2.379	Loss
AGC_NDR_NDR_STK38L_ST	O60285	NUAK1	Q9Y2H1	STK38L	S444	P443Q	443	Missense	proximal	-1	no	2.435	2.676	EPSD	ICGC;COSMIC	2.379	Up-regulation
AGC_NDR_NDR_STK38L_ST	O60285	NUAK1	Q9Y2H1	STK38L	S444	L442I	442	Missense	proximal	-2	no	2.435	2.339	EPSD	ICGC;COSMIC	2.379	Loss
AGC_NDR_NDR_STK38L_ST	O60285	NUAK1	Q9Y2H1	STK38L	S636	D634E	634	Missense	proximal	-2	no	2.432	2.383	EPSD	ICGC	2.379	Down-regulation
AGC_NDR_NDR_STK38L_ST	O60285	NUAK1	Q9Y2H1	STK38L	S636	L632M	632	Missense	distal	-4	no	2.432	2.338	EPSD	ICGC;COSMIC	2.379	Loss
AGC_NDR_NDR_STK38L_ST	Q96QF0	RAB3IP	Q9Y2H1	STK38L	S154	R160L	160	Missense	distal	6	no	3.223	3.321	EPSD	ICGC;COSMIC	2.379	Up-regulation
AGC_NDR_NDR_STK38L_ST	Q96QF0	RAB3IP	Q9Y2H1	STK38L	S154	R160Q	160	Missense	distal	6	no	3.223	3.330	EPSD	ICGC;COSMIC	2.379	Up-regulation
AGC_NDR_NDR_STK38L_ST	P46937	YAP1	Q9Y2H1	STK38L	S94	P99Q	99	Missense	distal	5	no	4.182	3.794	EPSD	ICGC;COSMIC	2.379	Down-regulation
AGC_NDR_NDR_STK38L_ST	P46937	YAP1	Q9Y2H1	STK38L	S105	T110S	110	Missense	distal	5	no	3.816	3.605	EPSD	ICGC;COSMIC	2.379	Down-regulation
AGC_NDR_NDR_STK38L_ST	P46937	YAP1	Q9Y2H1	STK38L	S105	P99Q	99	Missense	distal	-6	no	3.816	3.829	EPSD	ICGC;COSMIC	2.379	Up-regulation
AGC_NDR_NDR_STK38L_ST	P46937	YAP1	Q9Y2H1	STK38L	S109	T110S	110	Missense	proximal	1	no	2.488	2.569	EPSD	ICGC;COSMIC	2.379	Up-regulation
AGC_NDR_NDR_STK38L_ST	P46937	YAP1	Q9Y2H1	STK38L	S109	A115T	115	Missense	distal	6	no	2.488	2.508	EPSD	ICGC	2.379	Up-regulation
AGC_NDR_NDR_STK38L_ST	P46937	YAP1	Q9Y2H1	STK38L	S127	Q133L	133	Missense	distal	6	no	9.436	9.426	PhosphoSitePlus	ICGC;COSMIC	2.379	Down-regulation
AGC_NDR_NDR_STK38L_ST	P46937	YAP1	Q9Y2H1	STK38L	S127	V123F	123	Missense	distal	-4	no	9.436	9.325	PhosphoSitePlus	ICGC	2.379	Down-regulation
AGC_NDR_NDR_STK38L_ST	P46937	YAP1	Q9Y2H1	STK38L	S127	L134F	134	Missense	distal	7	no	9.436	9.421	PhosphoSitePlus	ICGC;COSMIC	2.379	Down-regulation
AGC_NDR_NDR_STK38L_ST	P46937	YAP1	Q9Y2H1	STK38L	S127	H126R	126	Missense	proximal	-1	no	9.436	9.312	PhosphoSitePlus	ICGC;COSMIC	2.379	Down-regulation
AGC_NDR_NDR_STK38L_ST	P46937	YAP1	Q9Y2H1	STK38L	T154	R161L	161	Missense	distal	7	no	2.447	2.454	EPSD	ICGC	2.379	Up-regulation
AGC_NDR_NDR_STK38L_ST	P46937	YAP1	Q9Y2H1	STK38L	S336	R331W	331	Missense	distal	-5	no	3.535	2.741	EPSD	ICGC;COSMIC	2.379	Down-regulation
AGC_NDR_NDR_STK38L_ST	P46937	YAP1	Q9Y2H1	STK38L	T378	Q372R	372	Missense	distal	-6	no	3.593	3.589	EPSD	ICGC;COSMIC	2.379	Down-regulation
AGC_NDR_NDR_STK38L_ST	P46937	YAP1	Q9Y2H1	STK38L	T378	F385S	385	Missense	distal	7	no	3.593	3.567	EPSD	ICGC	2.379	Down-regulation
AGC_NDR_NDR_STK38L_ST	P46937	YAP1	Q9Y2H1	STK38L	T378	Q372K	372	Missense	distal	-6	no	3.593	3.579	EPSD	ICGC;COSMIC	2.379	Down-regulation
AGC_NDR_NDR_STK38L_ST	P46937	YAP1	Q9Y2H1	STK38L	S397	L402P	402	Missense	distal	5	no	7.869	7.944	EPSD	ICGC;COSMIC	2.379	Up-regulation
AGC_NDR_NDR_STK38L_ST	P46937	YAP1	Q9Y2H1	STK38L	S397	R394Q	394	Missense	distal	-3	no	7.869	7.726	EPSD	ICGC;COSMIC	2.379	Down-regulation
AGC_NDR_NDR_STK38L_ST	P46937	YAP1	Q9Y2H1	STK38L	S397	S397I	397	Missense	central	0	yes	7.869	0.000	EPSD	ICGC	2.379	Loss
AGC_NDR_NDR_STK38L_ST	P46937	YAP1	Q9Y2H1	STK38L	S397	H392N	392	Missense	distal	-5	no	7.869	6.388	EPSD	ICGC;COSMIC	2.379	Down-regulation
AGC_NDR_NDR_STK38L_ST	P46937	YAP1	Q9Y2H1	STK38L	S397	T398A	398	Missense	proximal	1	no	7.869	7.823	EPSD	ICGC;COSMIC	2.379	Down-regulation
AGC_NDR_NDR_STK38L_ST	P46937	YAP1	Q9Y2H1	STK38L	S499	T493A	493	Missense	distal	-6	no	2.920	2.954	EPSD	ICGC;COSMIC	2.379	Up-regulation
AGC_NDR_NDR_STK38L_ST	Q9Y2H1	STK38L	Q9Y2H1	STK38L	T8	P12S	12	Missense	distal	4	no	1.179	2.435	EPSD	ICGC	2.379	Gain
AGC_NDR_NDR_STK38L_ST	Q9Y2H1	STK38L	Q9Y2H1	STK38L	T450	R452L	452	Missense	proximal	2	no	3.445	3.355	EPSD	ICGC	2.379	Down-regulation
CK1_CK1_CK1-D_CSNK1E_ST	O15055	PER2	P49674	CSNK1E	T43	T43N	43	Missense	central	0	yes	27.802	0.000	EPSD	ICGC	22.404	Loss
CK1_CK1_CK1-D_CSNK1E_ST	O15055	PER2	P49674	CSNK1E	T43	T49M	49	Missense	distal	6	no	27.802	30.439	EPSD	ICGC	22.404	Up-regulation
CK1_CK1_CK1-D_CSNK1E_ST	O15055	PER2	P49674	CSNK1E	S56	D59E	59	Missense	distal	3	no	22.846	16.642	EPSD	ICGC	22.404	Loss
CK1_CK1_CK1-D_CSNK1E_ST	O15055	PER2	P49674	CSNK1E	S56	T49M	49	Missense	distal	-7	no	22.846	22.841	EPSD	ICGC	22.404	Down-regulation
CK1_CK1_CK1-D_CSNK1E_ST	O15055	PER2	P49674	CSNK1E	S259	D258E	258	Missense	proximal	-1	no	21.162	23.323	EPSD	ICGC	22.404	Gain
CK1_CK1_CK1-D_CSNK1E_ST	O15055	PER2	P49674	CSNK1E	S662	P657Q	657	Missense	distal	-5	no	39.470	39.376	PhosphoSitePlus;EPSD	ICGC	22.404	Down-regulation
CK1_CK1_CK1-D_CSNK1E_ST	O15055	PER2	P49674	CSNK1E	S662	Q669K	669	Missense	distal	7	no	39.470	39.605	PhosphoSitePlus;EPSD	ICGC;COSMIC	22.404	Up-regulation
CK1_CK1_CK1-D_CSNK1E_ST	O15055	PER2	P49674	CSNK1E	S662	A664E	664	Missense	proximal	2	no	39.470	36.949	PhosphoSitePlus;EPSD	ICGC	22.404	Down-regulation
CK1_CK1_CK1-D_CSNK1E_ST	O15055	PER2	P49674	CSNK1E	S665	Q669K	669	Missense	distal	4	no	39.530	39.370	EPSD;PhosphoSitePlus	ICGC;COSMIC	22.404	Down-regulation
CK1_CK1_CK1-D_CSNK1E_ST	O15055	PER2	P49674	CSNK1E	S665	A664E	664	Missense	proximal	-1	no	39.530	36.327	EPSD;PhosphoSitePlus	ICGC	22.404	Down-regulation
CK1_CK1_CK1-D_CSNK1E_ST	O15055	PER2	P49674	CSNK1E	S668	Q669K	669	Missense	proximal	1	no	35.036	35.635	EPSD;PhosphoSitePlus	ICGC;COSMIC	22.404	Up-regulation
CK1_CK1_CK1-D_CSNK1E_ST	O15055	PER2	P49674	CSNK1E	S668	A664E	664	Missense	distal	-4	no	35.036	33.959	EPSD;PhosphoSitePlus	ICGC	22.404	Down-regulation
CK1_CK1_CK1-D_CSNK1E_ST	O15055	PER2	P49674	CSNK1E	S696	A695E	695	Missense	proximal	-1	no	23.574	20.371	EPSD	ICGC;COSMIC	22.404	Loss
CK1_CK1_CK1-D_CSNK1E_ST	O15055	PER2	P49674	CSNK1E	S696	C703Y	703	Missense	distal	7	no	23.574	24.096	EPSD	ICGC	22.404	Up-regulation
CK1_CK1_CK1-D_CSNK1E_ST	O15055	PER2	P49674	CSNK1E	S696	E699D	699	Missense	distal	3	no	23.574	29.778	EPSD	ICGC	22.404	Up-regulation
CK1_CK1_CK1-D_CSNK1E_ST	O15055	PER2	P49674	CSNK1E	S971	R966W	966	Missense	distal	-5	no	24.632	23.822	EPSD	ICGC;COSMIC	22.404	Down-regulation
CK1_CK1_CK1-D_CSNK1E_ST	O15055	PER2	P49674	CSNK1E	S971	P970Q	970	Missense	proximal	-1	no	24.632	22.121	EPSD	ICGC;COSMIC	22.404	Loss
CK1_CK1_CK1-D_CSNK1E_ST	O15055	PER2	P49674	CSNK1E	S971	P978L	978	Missense	distal	7	no	24.632	25.017	EPSD	ICGC	22.404	Up-regulation
CK1_CK1_CK1-D_CSNK1E_ST	O15055	PER2	P49674	CSNK1E	S971	R966Q	966	Missense	distal	-5	no	24.632	25.051	EPSD	ICGC	22.404	Up-regulation
CK1_CK1_CK1-D_CSNK1E_ST	O15055	PER2	P49674	CSNK1E	T1013	M1007T	1007	Missense	distal	-6	no	27.830	27.513	EPSD	ICGC;COSMIC;GDSC	22.404	Down-regulation
CK1_CK1_CK1-D_CSNK1E_ST	O15055	PER2	P49674	CSNK1E	T1013	G1008E	1008	Missense	distal	-5	no	27.830	27.516	EPSD	ICGC	22.404	Down-regulation
CK1_CK1_CK1-D_CSNK1E_ST	Q92997	DVL3	P49674	CSNK1E	S125	D130E	130	Missense	distal	5	no	29.683	29.814	EPSD	ICGC;COSMIC	22.404	Up-regulation
CK1_CK1_CK1-D_CSNK1E_ST	Q92997	DVL3	P49674	CSNK1E	S125	N131S	131	Missense	distal	6	no	29.683	32.875	EPSD	ICGC;COSMIC	22.404	Up-regulation
CK1_CK1_CK1-D_CSNK1E_ST	Q92997	DVL3	P49674	CSNK1E	S137	D130E	130	Missense	distal	-7	no	29.116	29.115	EPSD	ICGC;COSMIC	22.404	Down-regulation
CK1_CK1_CK1-D_CSNK1E_ST	Q92997	DVL3	P49674	CSNK1E	S137	N131S	131	Missense	distal	-6	no	29.116	29.549	EPSD	ICGC;COSMIC	22.404	Up-regulation
CK1_CK1_CK1-D_CSNK1E_ST	Q92997	DVL3	P49674	CSNK1E	S140	R145W	145	Missense	distal	5	no	24.188	24.823	EPSD	ICGC;COSMIC	22.404	Up-regulation
CK1_CK1_CK1-D_CSNK1E_ST	Q92997	DVL3	P49674	CSNK1E	S140	R147C	147	Missense	distal	7	no	24.188	24.250	EPSD	ICGC;COSMIC	22.404	Up-regulation
CK1_CK1_CK1-D_CSNK1E_ST	Q92997	DVL3	P49674	CSNK1E	S140	R147H	147	Missense	distal	7	no	24.188	24.320	EPSD	ICGC;COSMIC	22.404	Up-regulation
CK1_CK1_CK1-D_CSNK1E_ST	Q92997	DVL3	P49674	CSNK1E	S203	S199I	199	Missense	distal	-4	no	28.972	24.633	EPSD	ICGC	22.404	Down-regulation
CK1_CK1_CK1-D_CSNK1E_ST	Q92997	DVL3	P49674	CSNK1E	S203	S209C	209	Missense	distal	6	no	28.972	23.810	EPSD	ICGC;COSMIC	22.404	Down-regulation
CK1_CK1_CK1-D_CSNK1E_ST	Q92997	DVL3	P49674	CSNK1E	S204	S199I	199	Missense	distal	-5	no	26.567	25.568	EPSD	ICGC	22.404	Down-regulation
CK1_CK1_CK1-D_CSNK1E_ST	Q92997	DVL3	P49674	CSNK1E	S204	S209C	209	Missense	distal	5	no	26.567	27.673	EPSD	ICGC;COSMIC	22.404	Up-regulation
CK1_CK1_CK1-D_CSNK1E_ST	Q92997	DVL3	P49674	CSNK1E	S209	S209C	209	Missense	central	0	yes	36.405	0.000	EPSD	ICGC;COSMIC	22.404	Loss
CK1_CK1_CK1-D_CSNK1E_ST	Q92997	DVL3	P49674	CSNK1E	S234	S241F	241	Missense	distal	7	no	26.611	27.345	EPSD	ICGC;COSMIC	22.404	Up-regulation
CK1_CK1_CK1-D_CSNK1E_ST	Q92997	DVL3	P49674	CSNK1E	S234	R231W	231	Missense	distal	-3	no	26.611	25.278	EPSD	ICGC;COSMIC	22.404	Down-regulation
CK1_CK1_CK1-D_CSNK1E_ST	Q92997	DVL3	P49674	CSNK1E	S234	S236I	236	Missense	proximal	2	no	26.611	27.151	EPSD	ICGC	22.404	Up-regulation
CK1_CK1_CK1-D_CSNK1E_ST	Q92997	DVL3	P49674	CSNK1E	S237	S241F	241	Missense	distal	4	no	25.798	25.915	EPSD	ICGC;COSMIC	22.404	Up-regulation
CK1_CK1_CK1-D_CSNK1E_ST	Q92997	DVL3	P49674	CSNK1E	S237	R231W	231	Missense	distal	-6	no	25.798	25.507	EPSD	ICGC;COSMIC	22.404	Down-regulation
CK1_CK1_CK1-D_CSNK1E_ST	Q92997	DVL3	P49674	CSNK1E	S237	S236I	236	Missense	proximal	-1	no	25.798	24.562	EPSD	ICGC	22.404	Down-regulation
CK1_CK1_CK1-D_CSNK1E_ST	Q92997	DVL3	P49674	CSNK1E	T249	T251A	251	Missense	proximal	2	no	21.771	23.599	EPSD	ICGC	22.404	Gain
CK1_CK1_CK1-D_CSNK1E_ST	Q92997	DVL3	P49674	CSNK1E	S516	H509L	509	Missense	distal	-7	no	27.900	27.901	EPSD	ICGC;COSMIC	22.404	Up-regulation
CK1_CK1_CK1-D_CSNK1E_ST	Q92997	DVL3	P49674	CSNK1E	S564	S566G	566	Missense	proximal	2	no	24.646	23.355	EPSD	ICGC;COSMIC	22.404	Down-regulation
CK1_CK1_CK1-D_CSNK1E_ST	Q92997	DVL3	P49674	CSNK1E	S564	S559G	559	Missense	distal	-5	no	24.646	24.279	EPSD	ICGC;COSMIC	22.404	Down-regulation
CK1_CK1_CK1-D_CSNK1E_ST	Q92997	DVL3	P49674	CSNK1E	S567	S566G	566	Missense	proximal	-1	no	37.739	36.560	EPSD	ICGC;COSMIC	22.404	Down-regulation
CK1_CK1_CK1-D_CSNK1E_ST	Q92997	DVL3	P49674	CSNK1E	S633	R635H	635	Missense	proximal	2	no	23.284	24.605	EPSD;PhosphoSitePlus	ICGC;COSMIC	22.404	Up-regulation
CK1_CK1_CK1-D_CSNK1E_ST	Q92997	DVL3	P49674	CSNK1E	S633	E631K	631	Missense	proximal	-2	no	23.284	22.594	EPSD;PhosphoSitePlus	ICGC	22.404	Down-regulation
CK1_CK1_CK1-D_CSNK1E_ST	Q92997	DVL3	P49674	CSNK1E	S633	S639F	639	Missense	distal	6	no	23.284	20.078	EPSD;PhosphoSitePlus	ICGC	22.404	Loss
CK1_CK1_CK1-D_CSNK1E_ST	Q92997	DVL3	P49674	CSNK1E	S636	R635H	635	Missense	proximal	-1	no	26.308	26.863	EPSD;PhosphoSitePlus	ICGC;COSMIC	22.404	Up-regulation
CK1_CK1_CK1-D_CSNK1E_ST	Q92997	DVL3	P49674	CSNK1E	S636	E631K	631	Missense	distal	-5	no	26.308	25.426	EPSD;PhosphoSitePlus	ICGC	22.404	Down-regulation
CK1_CK1_CK1-D_CSNK1E_ST	Q92997	DVL3	P49674	CSNK1E	S636	S639F	639	Missense	distal	3	no	26.308	23.780	EPSD;PhosphoSitePlus	ICGC	22.404	Down-regulation
CK1_CK1_CK1-D_CSNK1E_ST	Q92997	DVL3	P49674	CSNK1E	S639	R635H	635	Missense	distal	-4	no	23.548	23.358	EPSD;PhosphoSitePlus	ICGC;COSMIC	22.404	Down-regulation
CK1_CK1_CK1-D_CSNK1E_ST	Q92997	DVL3	P49674	CSNK1E	S639	S639F	639	Missense	central	0	yes	23.548	0.000	EPSD;PhosphoSitePlus	ICGC	22.404	Loss
CK1_CK1_CK1-D_CSNK1E_ST	Q92997	DVL3	P49674	CSNK1E	S643	S639F	639	Missense	distal	-4	no	22.651	17.529	EPSD;PhosphoSitePlus	ICGC	22.404	Loss
CK1_CK1_CK1-D_CSNK1E_ST	Q92997	DVL3	P49674	CSNK1E	S697	R702H	702	Missense	distal	5	no	30.413	29.838	EPSD	ICGC;COSMIC	22.404	Down-regulation
CK1_CK1_CK1-D_CSNK1E_ST	Q92997	DVL3	P49674	CSNK1E	S697	A696P	696	Missense	proximal	-1	no	30.413	25.834	EPSD	ICGC	22.404	Down-regulation
CK1_CK1_CK1-D_CSNK1E_ST	Q92997	DVL3	P49674	CSNK1E	S697	A696S	696	Missense	proximal	-1	no	30.413	26.738	EPSD	ICGC;COSMIC	22.404	Down-regulation
CK1_CK1_CK1-D_CSNK1E_ST	O95863	SNAI1	P49674	CSNK1E	S107	S112F	112	Missense	distal	5	no	39.045	40.050	EPSD;PhosphoSitePlus	ICGC;COSMIC	22.404	Up-regulation
CK1_CK1_CK1-D_CSNK1E_ST	Q8TD43	TRPM4	P49674	CSNK1E	S104	R108L	108	Missense	distal	4	no	23.239	23.210	EPSD	ICGC	22.404	Down-regulation
CK1_CK1_CK1-D_CSNK1E_ST	Q8TD43	TRPM4	P49674	CSNK1E	S255	L253M	253	Missense	proximal	-2	no	22.910	26.099	EPSD	ICGC;COSMIC	22.404	Up-regulation
CK1_CK1_CK1-D_CSNK1E_ST	Q8TD43	TRPM4	P49674	CSNK1E	S255	R252H	252	Missense	distal	-3	no	22.910	19.966	EPSD	ICGC;COSMIC	22.404	Loss
CK1_CK1_CK1-D_CSNK1E_ST	Q8TD43	TRPM4	P49674	CSNK1E	S255	R250C	250	Missense	distal	-5	no	22.910	22.726	EPSD	ICGC	22.404	Down-regulation
CK1_CK1_CK1-D_CSNK1E_ST	Q8TD43	TRPM4	P49674	CSNK1E	S839	G835V	835	Missense	distal	-4	no	36.245	36.023	PhosphoSitePlus	ICGC	22.404	Down-regulation
CK1_CK1_CK1-D_CSNK1E_ST	Q8TD43	TRPM4	P49674	CSNK1E	S839	S839I	839	Missense	central	0	yes	36.245	0.000	PhosphoSitePlus	ICGC	22.404	Loss
CK1_CK1_CK1-D_CSNK1E_ST	Q8TD43	TRPM4	P49674	CSNK1E	S839	G838S	838	Missense	proximal	-1	no	36.245	37.425	PhosphoSitePlus	ICGC;COSMIC	22.404	Up-regulation
CK1_CK1_CK1-D_CSNK1E_ST	Q8TD43	TRPM4	P49674	CSNK1E	S1098	Q1100H	1100	Missense	proximal	2	no	24.945	24.434	EPSD	ICGC;COSMIC	22.404	Down-regulation
CK1_CK1_CK1-D_CSNK1E_ST	Q8TD43	TRPM4	P49674	CSNK1E	S1102	Q1100H	1100	Missense	proximal	-2	no	22.259	23.214	EPSD	ICGC;COSMIC	22.404	Gain
CK1_CK1_CK1-D_CSNK1E_ST	Q9Y6Q9	NCOA3	P49674	CSNK1E	S102	V100A	100	Missense	proximal	-2	no	34.349	36.335	PhosphoSitePlus	ICGC;COSMIC	22.404	Up-regulation
CK1_CK1_CK1-D_CSNK1E_ST	Q9Y6Q9	NCOA3	P49674	CSNK1E	S102	D109Y	109	Missense	distal	7	no	34.349	35.074	PhosphoSitePlus	ICGC	22.404	Up-regulation
CK1_CK1_CK1-D_CSNK1E_ST	Q9Y6Q9	NCOA3	P49674	CSNK1E	S102	Q105H	105	Missense	distal	3	no	34.349	29.446	PhosphoSitePlus	ICGC	22.404	Down-regulation
CK1_CK1_CK1-D_CSNK1E_ST	Q9Y6Q9	NCOA3	P49674	CSNK1E	S102	V100G	100	Missense	proximal	-2	no	34.349	33.275	PhosphoSitePlus	ICGC	22.404	Down-regulation
CK1_CK1_CK1-D_CSNK1E_ST	Q9Y6Q9	NCOA3	P49674	CSNK1E	S214	D210N	210	Missense	distal	-4	no	37.141	33.379	EPSD	ICGC;COSMIC	22.404	Down-regulation
CK1_CK1_CK1-D_CSNK1E_ST	Q9Y6Q9	NCOA3	P49674	CSNK1E	T282	D281Y	281	Missense	proximal	-1	no	26.682	22.343	EPSD	ICGC;COSMIC	22.404	Loss
CK1_CK1_CK1-D_CSNK1E_ST	Q9Y6Q9	NCOA3	P49674	CSNK1E	S287	D281Y	281	Missense	distal	-6	no	25.354	25.272	EPSD	ICGC;COSMIC	22.404	Down-regulation
CK1_CK1_CK1-D_CSNK1E_ST	Q9Y6Q9	NCOA3	P49674	CSNK1E	T425	S423N	423	Missense	proximal	-2	no	25.196	18.084	EPSD	ICGC;COSMIC	22.404	Loss
CK1_CK1_CK1-D_CSNK1E_ST	Q9Y6Q9	NCOA3	P49674	CSNK1E	T425	G418V	418	Missense	distal	-7	no	25.196	25.194	EPSD	ICGC	22.404	Down-regulation
CK1_CK1_CK1-D_CSNK1E_ST	Q9Y6Q9	NCOA3	P49674	CSNK1E	T425	G426V	426	Missense	proximal	1	no	25.196	25.859	EPSD	ICGC	22.404	Up-regulation
CK1_CK1_CK1-D_CSNK1E_ST	Q9Y6Q9	NCOA3	P49674	CSNK1E	T425	A431T	431	Missense	distal	6	no	25.196	24.309	EPSD	ICGC;COSMIC	22.404	Down-regulation
CK1_CK1_CK1-D_CSNK1E_ST	Q9Y6Q9	NCOA3	P49674	CSNK1E	S712	I713V	713	Missense	proximal	1	no	23.305	23.017	EPSD	ICGC;COSMIC	22.404	Down-regulation
CK1_CK1_CK1-D_CSNK1E_ST	Q9Y6Q9	NCOA3	P49674	CSNK1E	S712	T714A	714	Missense	proximal	2	no	23.305	25.132	EPSD	ICGC	22.404	Up-regulation
CK1_CK1_CK1-D_CSNK1E_ST	Q9Y6Q9	NCOA3	P49674	CSNK1E	S715	I713V	713	Missense	proximal	-2	no	25.096	24.757	EPSD	ICGC;COSMIC	22.404	Down-regulation
CK1_CK1_CK1-D_CSNK1E_ST	Q9Y6Q9	NCOA3	P49674	CSNK1E	S715	T714A	714	Missense	proximal	-1	no	25.096	30.871	EPSD	ICGC	22.404	Up-regulation
CK1_CK1_CK1-D_CSNK1E_ST	Q9Y6Q9	NCOA3	P49674	CSNK1E	S844	I848V	848	Missense	distal	4	no	28.117	28.252	EPSD	ICGC;COSMIC	22.404	Up-regulation
CK1_CK1_CK1-D_CSNK1E_ST	Q9Y6Q9	NCOA3	P49674	CSNK1E	S844	R849L	849	Missense	distal	5	no	28.117	28.074	EPSD	ICGC	22.404	Down-regulation
CK1_CK1_CK1-D_CSNK1E_ST	Q9Y6Q9	NCOA3	P49674	CSNK1E	S844	Q846H	846	Missense	proximal	2	no	28.117	27.606	EPSD	ICGC	22.404	Down-regulation
CK1_CK1_CK1-D_CSNK1E_ST	Q9Y6Q9	NCOA3	P49674	CSNK1E	S916	S917T	917	Missense	proximal	1	no	24.860	24.249	EPSD	ICGC;COSMIC	22.404	Down-regulation
CK1_CK1_CK1-D_CSNK1E_ST	Q9Y6Q9	NCOA3	P49674	CSNK1E	S916	V911M	911	Missense	distal	-5	no	24.860	25.377	EPSD	ICGC;COSMIC	22.404	Up-regulation
CK1_CK1_CK1-D_CSNK1E_ST	Q9Y6Q9	NCOA3	P49674	CSNK1E	S917	V911M	911	Missense	distal	-6	no	21.526	22.885	EPSD	ICGC;COSMIC	22.404	Gain
CK1_CK1_CK1-D_CSNK1E_ST	P49674	CSNK1E	P49674	CSNK1E	T44	K43M	43	Missense	proximal	-1	no	33.821	30.018	EPSD	ICGC;COSMIC	22.404	Down-regulation
CK1_CK1_CK1-D_CSNK1E_ST	P49674	CSNK1E	P49674	CSNK1E	S323	A324T	324	Missense	proximal	1	no	32.443	32.119	PhosphoSitePlus;EPSD	ICGC;COSMIC	22.404	Down-regulation
CK1_CK1_CK1-D_CSNK1E_ST	P49674	CSNK1E	P49674	CSNK1E	S323	R326Q	326	Missense	distal	3	no	32.443	31.009	PhosphoSitePlus;EPSD	ICGC	22.404	Down-regulation
CK1_CK1_CK1-D_CSNK1E_ST	P49674	CSNK1E	P49674	CSNK1E	T325	A324T	324	Missense	proximal	-1	no	34.999	29.224	EPSD;PhosphoSitePlus	ICGC;COSMIC	22.404	Down-regulation
CK1_CK1_CK1-D_CSNK1E_ST	P49674	CSNK1E	P49674	CSNK1E	T325	R326Q	326	Missense	proximal	1	no	34.999	34.611	EPSD;PhosphoSitePlus	ICGC	22.404	Down-regulation
CK1_CK1_CK1-D_CSNK1E_ST	P49674	CSNK1E	P49674	CSNK1E	T334	R340W	340	Missense	distal	6	no	36.881	31.925	EPSD;PhosphoSitePlus	ICGC;COSMIC	22.404	Down-regulation
CK1_CK1_CK1-D_CSNK1E_ST	P49674	CSNK1E	P49674	CSNK1E	T334	G335R	335	Missense	proximal	1	no	36.881	37.127	EPSD;PhosphoSitePlus	ICGC	22.404	Up-regulation
CK1_CK1_CK1-D_CSNK1E_ST	P49674	CSNK1E	P49674	CSNK1E	T337	R340W	340	Missense	distal	3	no	34.851	31.345	EPSD;PhosphoSitePlus	ICGC;COSMIC	22.404	Down-regulation
CK1_CK1_CK1-D_CSNK1E_ST	P49674	CSNK1E	P49674	CSNK1E	T337	G335R	335	Missense	proximal	-2	no	34.851	30.144	EPSD;PhosphoSitePlus	ICGC	22.404	Down-regulation
CK1_CK1_CK1-D_CSNK1E_ST	P49674	CSNK1E	P49674	CSNK1E	S350	A345T	345	Missense	distal	-5	no	25.032	24.369	EPSD	ICGC;COSMIC	22.404	Down-regulation
CK1_CK1_CK1-D_CSNK1E_ST	P49674	CSNK1E	P49674	CSNK1E	T351	A345T	345	Missense	distal	-6	no	26.172	26.500	EPSD	ICGC;COSMIC	22.404	Up-regulation
CK1_CK1_CK1-D_CSNK1E_ST	P49674	CSNK1E	P49674	CSNK1E	S368	R369W	369	Missense	proximal	1	no	35.358	35.015	EPSD;PhosphoSitePlus	ICGC;COSMIC	22.404	Down-regulation
CK1_CK1_CK1-D_CSNK1E_ST	P49674	CSNK1E	P49674	CSNK1E	S390	R396L	396	Missense	distal	6	no	23.913	20.580	EPSD	ICGC;COSMIC	22.404	Loss
CK1_CK1_CK1-D_CSNK1E_ST	P49674	CSNK1E	P49674	CSNK1E	S405	Q406K	406	Missense	proximal	1	no	24.727	25.326	EPSD;PhosphoSitePlus	ICGC	22.404	Up-regulation
CK1_CK1_CK1-D_CSNK1E_ST	O14641	DVL2	P49674	CSNK1E	T39	R37S	37	Missense	proximal	-2	no	15.769	22.677	EPSD	ICGC	22.404	Gain
CK1_CK1_CK1-D_CSNK1E_ST	O14641	DVL2	P49674	CSNK1E	S131	R132M	132	Missense	proximal	1	no	21.828	23.048	EPSD	ICGC	22.404	Gain
CK1_CK1_CK1-D_CSNK1E_ST	O14641	DVL2	P49674	CSNK1E	S218	T224K	224	Missense	distal	6	no	21.743	24.200	EPSD	ICGC	22.404	Gain
CK1_CK1_CK1-D_CSNK1E_ST	O14641	DVL2	P49674	CSNK1E	T224	T224K	224	Missense	central	0	yes	32.742	0.000	EPSD;PhosphoSitePlus	ICGC	22.404	Loss
CK1_CK1_CK1-D_CSNK1E_ST	O14641	DVL2	P49674	CSNK1E	T224	Q226K	226	Missense	proximal	2	no	32.742	32.476	EPSD;PhosphoSitePlus	ICGC	22.404	Down-regulation
CK1_CK1_CK1-D_CSNK1E_ST	O14641	DVL2	P49674	CSNK1E	S227	T224K	224	Missense	distal	-3	no	26.666	27.276	EPSD	ICGC	22.404	Up-regulation
CK1_CK1_CK1-D_CSNK1E_ST	O14641	DVL2	P49674	CSNK1E	S227	Q226K	226	Missense	proximal	-1	no	26.666	27.046	EPSD	ICGC	22.404	Up-regulation
CK1_CK1_CK1-D_CSNK1E_ST	O14641	DVL2	P49674	CSNK1E	S228	R235H	235	Missense	distal	7	no	35.464	35.596	EPSD	ICGC	22.404	Up-regulation
CK1_CK1_CK1-D_CSNK1E_ST	O14641	DVL2	P49674	CSNK1E	S228	T224K	224	Missense	distal	-4	no	35.464	31.354	EPSD	ICGC	22.404	Down-regulation
CK1_CK1_CK1-D_CSNK1E_ST	O14641	DVL2	P49674	CSNK1E	S228	R235S	235	Missense	distal	7	no	35.464	35.162	EPSD	ICGC;COSMIC	22.404	Down-regulation
CK1_CK1_CK1-D_CSNK1E_ST	O14641	DVL2	P49674	CSNK1E	S228	Q226K	226	Missense	proximal	-2	no	35.464	37.160	EPSD	ICGC	22.404	Up-regulation
CK1_CK1_CK1-D_CSNK1E_ST	O14641	DVL2	P49674	CSNK1E	S252	V256I	256	Missense	distal	4	no	22.926	22.791	EPSD	ICGC;COSMIC	22.404	Down-regulation
CK1_CK1_CK1-D_CSNK1E_ST	O14641	DVL2	P49674	CSNK1E	S255	V256I	256	Missense	proximal	1	no	30.144	30.431	EPSD	ICGC;COSMIC	22.404	Up-regulation
CK1_CK1_CK1-D_CSNK1E_ST	O14641	DVL2	P49674	CSNK1E	S286	G292R	292	Missense	distal	6	no	24.069	26.760	EPSD	ICGC	22.404	Up-regulation
CK1_CK1_CK1-D_CSNK1E_ST	O14641	DVL2	P49674	CSNK1E	S398	P394Q	394	Missense	distal	-4	no	39.333	39.415	EPSD	ICGC	22.404	Up-regulation
CK1_CK1_CK1-D_CSNK1E_ST	O14641	DVL2	P49674	CSNK1E	S398	M399V	399	Missense	proximal	1	no	39.333	38.530	EPSD	ICGC	22.404	Down-regulation
CK1_CK1_CK1-D_CSNK1E_ST	O14641	DVL2	P49674	CSNK1E	T401	P394Q	394	Missense	distal	-7	no	27.722	27.721	EPSD	ICGC	22.404	Down-regulation
CK1_CK1_CK1-D_CSNK1E_ST	O14641	DVL2	P49674	CSNK1E	T401	M399V	399	Missense	proximal	-2	no	27.722	30.020	EPSD	ICGC	22.404	Up-regulation
CK1_CK1_CK1-D_CSNK1E_ST	O14641	DVL2	P49674	CSNK1E	S404	M399V	399	Missense	distal	-5	no	31.747	31.230	EPSD	ICGC	22.404	Down-regulation
CK1_CK1_CK1-D_CSNK1E_ST	O14641	DVL2	P49674	CSNK1E	S580	E587D	587	Missense	distal	7	no	26.817	26.794	EPSD	ICGC;COSMIC	22.404	Down-regulation
CK1_CK1_CK1-D_CSNK1E_ST	O14641	DVL2	P49674	CSNK1E	S580	G578V	578	Missense	proximal	-2	no	26.817	27.891	EPSD	ICGC;COSMIC	22.404	Up-regulation
CK1_CK1_CK1-D_CSNK1E_ST	O14641	DVL2	P49674	CSNK1E	S580	G578W	578	Missense	proximal	-2	no	26.817	18.430	EPSD	ICGC;COSMIC	22.404	Loss
CK1_CK1_CK1-D_CSNK1E_ST	O14641	DVL2	P49674	CSNK1E	S583	E587D	587	Missense	distal	4	no	41.730	41.625	EPSD	ICGC;COSMIC	22.404	Down-regulation
CK1_CK1_CK1-D_CSNK1E_ST	O14641	DVL2	P49674	CSNK1E	S583	G578V	578	Missense	distal	-5	no	41.730	41.496	EPSD	ICGC;COSMIC	22.404	Down-regulation
CK1_CK1_CK1-D_CSNK1E_ST	O14641	DVL2	P49674	CSNK1E	S583	G578W	578	Missense	distal	-5	no	41.730	39.908	EPSD	ICGC;COSMIC	22.404	Down-regulation
CK1_CK1_CK1-D_CSNK1E_ST	O14641	DVL2	P49674	CSNK1E	S591	E587D	587	Missense	distal	-4	no	27.923	26.336	EPSD	ICGC;COSMIC	22.404	Down-regulation
CK1_CK1_CK1-D_CSNK1E_ST	O14641	DVL2	P49674	CSNK1E	S594	E587D	587	Missense	distal	-7	no	27.965	27.966	EPSD	ICGC;COSMIC	22.404	Up-regulation
CK1_CK1_CK1-D_CSNK1E_ST	O14641	DVL2	P49674	CSNK1E	S616	G619D	619	Missense	distal	3	no	25.336	28.822	EPSD	ICGC;COSMIC	22.404	Up-regulation
CK1_CK1_CK1-D_CSNK1E_ST	O14641	DVL2	P49674	CSNK1E	S618	G619D	619	Missense	proximal	1	no	31.832	32.316	EPSD	ICGC;COSMIC	22.404	Up-regulation
CK1_CK1_CK1-D_CSNK1E_ST	O14641	DVL2	P49674	CSNK1E	S620	G619D	619	Missense	proximal	-1	no	24.754	24.244	EPSD	ICGC;COSMIC	22.404	Down-regulation
CK1_CK1_CK1-D_CSNK1E_ST	O14641	DVL2	P49674	CSNK1E	S622	G619D	619	Missense	distal	-3	no	39.245	39.141	EPSD	ICGC;COSMIC	22.404	Down-regulation
CK1_CK1_CK1-D_CSNK1E_ST	O14641	DVL2	P49674	CSNK1E	S638	P645R	645	Missense	distal	7	no	27.041	27.139	EPSD	ICGC;COSMIC	22.404	Up-regulation
CK1_CK1_CK1-D_CSNK1E_ST	O14641	DVL2	P49674	CSNK1E	S641	P645R	645	Missense	distal	4	no	33.310	33.449	EPSD	ICGC;COSMIC	22.404	Up-regulation
CK1_CK1_CK1-D_CSNK1E_ST	O14641	DVL2	P49674	CSNK1E	T652	R659L	659	Missense	distal	7	no	25.567	25.854	EPSD	ICGC;COSMIC	22.404	Up-regulation
CK1_CK1_CK1-D_CSNK1E_ST	O14641	DVL2	P49674	CSNK1E	T652	G654C	654	Missense	proximal	2	no	25.567	25.055	EPSD	ICGC;COSMIC	22.404	Down-regulation
CK1_CK1_CK1-D_CSNK1E_ST	O14641	DVL2	P49674	CSNK1E	T652	P645R	645	Missense	distal	-7	no	25.567	25.561	EPSD	ICGC;COSMIC	22.404	Down-regulation
CK1_CK1_CK1-D_CSNK1E_ST	O75581	LRP6	P49674	CSNK1E	S122	R118W	118	Missense	distal	-4	no	27.140	21.234	EPSD	ICGC;COSMIC	22.404	Loss
CK1_CK1_CK1-D_CSNK1E_ST	O75581	LRP6	P49674	CSNK1E	S122	S127T	127	Missense	distal	5	no	27.140	27.095	EPSD	ICGC	22.404	Down-regulation
CK1_CK1_CK1-D_CSNK1E_ST	O75581	LRP6	P49674	CSNK1E	S172	N178K	178	Missense	distal	6	no	21.764	22.828	EPSD	ICGC	22.404	Gain
CK1_CK1_CK1-D_CSNK1E_ST	P12830	CDH1	P49674	CSNK1E	S237	E243D	243	Missense	distal	6	no	20.337	23.967	EPSD	ICGC	22.404	Gain
CK1_CK1_CK1-D_CSNK1E_ST	P25054	APC	P49674	CSNK1E	S5	K11N	11	Missense	distal	6	no	23.043	21.979	EPSD	ICGC	22.404	Loss
CK1_CK1_CK1-D_CSNK1E_ST	P25054	APC	P49674	CSNK1E	S5	A4T	4	Missense	proximal	-1	no	23.043	17.268	EPSD	ICGC;COSMIC	22.404	Loss
CK1_CK1_CK1-D_CSNK1E_ST	P25054	APC	P49674	CSNK1E	S290	S294Y	294	Missense	distal	4	no	32.387	32.536	EPSD	ICGC;COSMIC	22.404	Up-regulation
CK1_CK1_CK1-D_CSNK1E_ST	P25054	APC	P49674	CSNK1E	S290	S293I	293	Missense	distal	3	no	32.387	28.389	EPSD	ICGC	22.404	Down-regulation
CK1_CK1_CK1-D_CSNK1E_ST	P25054	APC	P49674	CSNK1E	S293	S294Y	294	Missense	proximal	1	no	26.270	25.375	EPSD	ICGC;COSMIC	22.404	Down-regulation
CK1_CK1_CK1-D_CSNK1E_ST	P25054	APC	P49674	CSNK1E	S293	S293I	293	Missense	central	0	yes	26.270	0.000	EPSD	ICGC	22.404	Loss
CK1_CK1_CK1-D_CSNK1E_ST	P25054	APC	P49674	CSNK1E	S296	S294Y	294	Missense	proximal	-2	no	24.861	19.326	EPSD	ICGC;COSMIC	22.404	Loss
CK1_CK1_CK1-D_CSNK1E_ST	P25054	APC	P49674	CSNK1E	S296	R302P	302	Missense	distal	6	no	24.861	25.323	EPSD	ICGC	22.404	Up-regulation
CK1_CK1_CK1-D_CSNK1E_ST	P25054	APC	P49674	CSNK1E	S296	R302L	302	Missense	distal	6	no	24.861	21.528	EPSD	ICGC	22.404	Loss
CK1_CK1_CK1-D_CSNK1E_ST	P25054	APC	P49674	CSNK1E	S296	S293I	293	Missense	distal	-3	no	24.861	24.341	EPSD	ICGC	22.404	Down-regulation
CK1_CK1_CK1-D_CSNK1E_ST	P25054	APC	P49674	CSNK1E	S747	S748I	748	Missense	proximal	1	no	32.569	32.540	EPSD	ICGC	22.404	Down-regulation
CK1_CK1_CK1-D_CSNK1E_ST	P25054	APC	P49674	CSNK1E	S747	P750S	750	Missense	distal	3	no	32.569	33.551	EPSD	ICGC;COSMIC	22.404	Up-regulation
CK1_CK1_CK1-D_CSNK1E_ST	P25054	APC	P49674	CSNK1E	S987	Y986S	986	Missense	proximal	-1	no	20.998	27.028	EPSD	ICGC	22.404	Gain
CK1_CK1_CK1-D_CSNK1E_ST	P25054	APC	P49674	CSNK1E	S1117	R1114Q	1114	Missense	distal	-3	no	22.552	22.391	EPSD	ICGC;COSMIC	22.404	Loss
CK1_CK1_CK1-D_CSNK1E_ST	P25054	APC	P49674	CSNK1E	S1117	G1120E	1120	Missense	distal	3	no	22.552	19.834	EPSD	ICGC;COSMIC	22.404	Loss
CK1_CK1_CK1-D_CSNK1E_ST	P25054	APC	P49674	CSNK1E	S1219	T1218A	1218	Missense	proximal	-1	no	23.419	29.195	EPSD	ICGC;GDSC;CCLE	22.404	Up-regulation
CK1_CK1_CK1-D_CSNK1E_ST	P25054	APC	P49674	CSNK1E	S1279	R1273I	1273	Missense	distal	-6	no	36.697	38.196	PhosphoSitePlus;EPSD	ICGC	22.404	Up-regulation
CK1_CK1_CK1-D_CSNK1E_ST	P25054	APC	P49674	CSNK1E	S1340	S1346L	1346	Missense	distal	6	no	23.203	20.046	EPSD	ICGC;COSMIC	22.404	Loss
CK1_CK1_CK1-D_CSNK1E_ST	P25054	APC	P49674	CSNK1E	S1340	A1347T	1347	Missense	distal	7	no	23.203	23.311	EPSD	ICGC;COSMIC	22.404	Up-regulation
CK1_CK1_CK1-D_CSNK1E_ST	P25054	APC	P49674	CSNK1E	S1340	S1334F	1334	Missense	distal	-6	no	23.203	22.053	EPSD	ICGC;COSMIC	22.404	Loss
CK1_CK1_CK1-D_CSNK1E_ST	P25054	APC	P49674	CSNK1E	S1344	S1346L	1346	Missense	proximal	2	no	23.502	20.977	EPSD	ICGC;COSMIC	22.404	Loss
CK1_CK1_CK1-D_CSNK1E_ST	P25054	APC	P49674	CSNK1E	S1344	A1347T	1347	Missense	distal	3	no	23.502	24.524	EPSD	ICGC;COSMIC	22.404	Up-regulation
CK1_CK1_CK1-D_CSNK1E_ST	P25054	APC	P49674	CSNK1E	T1368	A1366V	1366	Missense	proximal	-2	no	27.840	25.854	EPSD	ICGC;COSMIC	22.404	Down-regulation
CK1_CK1_CK1-D_CSNK1E_ST	P25054	APC	P49674	CSNK1E	S1389	R1386I	1386	Missense	distal	-3	no	25.057	26.375	EPSD	ICGC	22.404	Up-regulation
CK1_CK1_CK1-D_CSNK1E_ST	P25054	APC	P49674	CSNK1E	S1389	T1388A	1388	Missense	proximal	-1	no	25.057	30.833	EPSD	ICGC;COSMIC	22.404	Up-regulation
CK1_CK1_CK1-D_CSNK1E_ST	P25054	APC	P49674	CSNK1E	S1392	R1399S	1399	Missense	distal	7	no	34.913	34.612	EPSD;PhosphoSitePlus	ICGC;COSMIC	22.404	Down-regulation
CK1_CK1_CK1-D_CSNK1E_ST	P25054	APC	P49674	CSNK1E	S1392	R1386I	1386	Missense	distal	-6	no	34.913	36.413	EPSD;PhosphoSitePlus	ICGC	22.404	Up-regulation
CK1_CK1_CK1-D_CSNK1E_ST	P25054	APC	P49674	CSNK1E	S1392	T1388A	1388	Missense	distal	-4	no	34.913	37.447	EPSD;PhosphoSitePlus	ICGC;COSMIC	22.404	Up-regulation
CK1_CK1_CK1-D_CSNK1E_ST	P25054	APC	P49674	CSNK1E	S1392	R1399C	1399	Missense	distal	7	no	34.913	34.975	EPSD;PhosphoSitePlus	ICGC;COSMIC;CCLE	22.404	Up-regulation
CK1_CK1_CK1-D_CSNK1E_ST	P25054	APC	P49674	CSNK1E	S1539	G1534W	1534	Missense	distal	-5	no	23.087	21.265	EPSD	ICGC;COSMIC	22.404	Loss
CK1_CK1_CK1-D_CSNK1E_ST	P25054	APC	P49674	CSNK1E	S1539	E1536D	1536	Missense	distal	-3	no	23.087	25.633	EPSD	ICGC;COSMIC	22.404	Up-regulation
CK1_CK1_CK1-D_CSNK1E_ST	P25054	APC	P49674	CSNK1E	S1754	S1756F	1756	Missense	proximal	2	no	25.033	23.846	EPSD	ICGC	22.404	Down-regulation
CK1_CK1_CK1-D_CSNK1E_ST	P25054	APC	P49674	CSNK1E	S1757	S1756F	1756	Missense	proximal	-1	no	26.313	18.607	EPSD	ICGC	22.404	Loss
CK1_CK1_CK1-D_CSNK1E_ST	P25054	APC	P49674	CSNK1E	S2110	I2111T	2111	Missense	proximal	1	no	29.100	28.517	EPSD	ICGC;COSMIC	22.404	Down-regulation
CK1_CK1_CK1-D_CSNK1E_ST	P25054	APC	P49674	CSNK1E	S2241	G2235V	2235	Missense	distal	-6	no	30.815	30.503	EPSD	ICGC;COSMIC	22.404	Down-regulation
CK1_CK1_CK1-D_CSNK1E_ST	P25054	APC	P49674	CSNK1E	S2302	R2305T	2305	Missense	distal	3	no	23.817	20.722	EPSD	ICGC;COSMIC	22.404	Loss
CK1_CK1_CK1-D_CSNK1E_ST	P25054	APC	P49674	CSNK1E	S2304	R2305T	2305	Missense	proximal	1	no	23.361	23.482	EPSD	ICGC;COSMIC	22.404	Up-regulation
CK1_CK1_CK1-D_CSNK1E_ST	P25054	APC	P49674	CSNK1E	S2304	R2311I	2311	Missense	distal	7	no	23.361	23.417	EPSD	ICGC;COSMIC	22.404	Up-regulation
CK1_CK1_CK1-D_CSNK1E_ST	P25054	APC	P49674	CSNK1E	S2307	R2305T	2305	Missense	proximal	-2	no	21.287	25.407	EPSD	ICGC;COSMIC	22.404	Gain
CK1_CK1_CK1-D_CSNK1E_ST	P25054	APC	P49674	CSNK1E	S2359	M2364I	2364	Missense	distal	5	no	22.635	23.419	EPSD	ICGC;COSMIC	22.404	Up-regulation
CK1_CK1_CK1-D_CSNK1E_ST	P25054	APC	P49674	CSNK1E	S2359	K2357T	2357	Missense	proximal	-2	no	22.635	23.838	EPSD	ICGC;COSMIC	22.404	Up-regulation
CK1_CK1_CK1-D_CSNK1E_ST	P25054	APC	P49674	CSNK1E	S2425	S2432L	2432	Missense	distal	7	no	32.289	32.878	EPSD	ICGC;COSMIC	22.404	Up-regulation
CK1_CK1_CK1-D_CSNK1E_ST	P25054	APC	P49674	CSNK1E	S2425	R2431K	2431	Missense	distal	6	no	32.289	29.985	EPSD	ICGC;COSMIC	22.404	Down-regulation
CK1_CK1_CK1-D_CSNK1E_ST	P25054	APC	P49674	CSNK1E	S2464	S2464C	2464	Missense	central	0	yes	27.851	0.000	EPSD	ICGC;COSMIC	22.404	Loss
CK1_CK1_CK1-D_CSNK1E_ST	P25054	APC	P49674	CSNK1E	S2464	R2470I	2470	Missense	distal	6	no	27.851	24.075	EPSD	ICGC	22.404	Down-regulation
CK1_CK1_CK1-D_CSNK1E_ST	P25054	APC	P49674	CSNK1E	S2464	S2469F	2469	Missense	distal	5	no	27.851	28.856	EPSD	ICGC;COSMIC	22.404	Up-regulation
CK1_CK1_CK1-D_CSNK1E_ST	P25054	APC	P49674	CSNK1E	S2464	S2459F	2459	Missense	distal	-5	no	27.851	26.132	EPSD	ICGC	22.404	Down-regulation
CK1_CK1_CK1-D_CSNK1E_ST	P25054	APC	P49674	CSNK1E	S2473	R2470I	2470	Missense	distal	-3	no	31.375	32.693	EPSD	ICGC	22.404	Up-regulation
CK1_CK1_CK1-D_CSNK1E_ST	P25054	APC	P49674	CSNK1E	S2473	S2469F	2469	Missense	distal	-4	no	31.375	26.253	EPSD	ICGC;COSMIC	22.404	Down-regulation
CK1_CK1_CK1-D_CSNK1E_ST	P25054	APC	P49674	CSNK1E	T2546	T2546I	2546	Missense	central	0	yes	24.642	0.000	EPSD	ICGC;COSMIC	22.404	Loss
CK1_CK1_CK1-D_CSNK1E_ST	P25054	APC	P49674	CSNK1E	T2546	R2549C	2549	Missense	distal	3	no	24.642	17.594	EPSD	ICGC;COSMIC	22.404	Loss
CK1_CK1_CK1-D_CSNK1E_ST	P25054	APC	P49674	CSNK1E	T2563	R2566K	2566	Missense	distal	3	no	24.739	21.267	EPSD	ICGC	22.404	Loss
CK1_CK1_CK1-D_CSNK1E_ST	P25054	APC	P49674	CSNK1E	S2569	R2566K	2566	Missense	distal	-3	no	23.725	24.278	EPSD	ICGC	22.404	Up-regulation
CK1_CK1_CK1-D_CSNK1E_ST	P25054	APC	P49674	CSNK1E	S2577	S2581R	2581	Missense	distal	4	no	25.007	25.181	EPSD	ICGC;COSMIC	22.404	Up-regulation
CK1_CK1_CK1-D_CSNK1E_ST	P25054	APC	P49674	CSNK1E	S2580	S2581R	2581	Missense	proximal	1	no	32.695	31.962	EPSD	ICGC;COSMIC	22.404	Down-regulation
CK1_CK1_CK1-D_CSNK1E_ST	P25054	APC	P49674	CSNK1E	S2594	S2601R	2601	Missense	distal	7	no	22.380	22.681	EPSD	ICGC;COSMIC	22.404	Gain
CK1_CK1_CK1-D_CSNK1E_ST	P25054	APC	P49674	CSNK1E	S2632	V2630I	2630	Missense	proximal	-2	no	31.939	32.278	EPSD	ICGC;COSMIC	22.404	Up-regulation
CK1_CK1_CK1-D_CSNK1E_ST	P25054	APC	P49674	CSNK1E	S2632	S2625C	2625	Missense	distal	-7	no	31.939	31.936	EPSD	ICGC	22.404	Down-regulation
CK1_CK1_CK1-D_CSNK1E_ST	P25054	APC	P49674	CSNK1E	S2632	G2633C	2633	Missense	proximal	1	no	31.939	32.349	EPSD	ICGC;COSMIC	22.404	Up-regulation
CK1_CK1_CK1-D_CSNK1E_ST	P25054	APC	P49674	CSNK1E	S2793	R2791W	2791	Missense	proximal	-2	no	26.193	22.513	EPSD	ICGC;COSMIC	22.404	Down-regulation
CK1_CK1_CK1-D_CSNK1E_ST	P25054	APC	P49674	CSNK1E	S2793	S2793I	2793	Missense	central	0	yes	26.193	0.000	EPSD	ICGC	22.404	Loss
CK1_CK1_CK1-D_CSNK1E_ST	P25054	APC	P49674	CSNK1E	S2793	S2794I	2794	Missense	proximal	1	no	26.193	26.164	EPSD	ICGC;COSMIC	22.404	Down-regulation
CK1_CK1_CK1-D_CSNK1E_ST	P25054	APC	P49674	CSNK1E	S2797	R2791W	2791	Missense	distal	-6	no	31.982	31.692	EPSD	ICGC;COSMIC	22.404	Down-regulation
CK1_CK1_CK1-D_CSNK1E_ST	P25054	APC	P49674	CSNK1E	S2797	S2793I	2793	Missense	distal	-4	no	31.982	27.644	EPSD	ICGC	22.404	Down-regulation
CK1_CK1_CK1-D_CSNK1E_ST	P25054	APC	P49674	CSNK1E	S2797	S2794I	2794	Missense	distal	-3	no	31.982	31.463	EPSD	ICGC;COSMIC	22.404	Down-regulation
CK1_CK1_CK1-D_CSNK1E_ST	P25054	APC	P49674	CSNK1E	T2798	R2791W	2791	Missense	distal	-7	no	23.150	23.152	EPSD	ICGC;COSMIC	22.404	Up-regulation
CK1_CK1_CK1-D_CSNK1E_ST	P25054	APC	P49674	CSNK1E	T2798	S2793I	2793	Missense	distal	-5	no	23.150	22.152	EPSD	ICGC	22.404	Loss
CK1_CK1_CK1-D_CSNK1E_ST	P25054	APC	P49674	CSNK1E	T2798	S2794I	2794	Missense	distal	-4	no	23.150	18.812	EPSD	ICGC;COSMIC	22.404	Loss
CK1_CK1_CK1-D_CSNK1E_ST	P35222	CTNNB1	P49674	CSNK1E	S250	L252H	252	Missense	proximal	2	no	24.069	25.131	EPSD	ICGC;COSMIC	22.404	Up-regulation
CK1_CK1_CK1-D_CSNK1E_ST	Q13541	EIF4EBP1	P49674	CSNK1E	S6	C7S	7	Missense	proximal	1	no	21.856	22.425	EPSD	ICGC;COSMIC	22.404	Gain
CK1_CK1_CK1-D_CSNK1E_ST	Q13541	EIF4EBP1	P49674	CSNK1E	S8	C7S	7	Missense	proximal	-1	no	19.598	26.870	EPSD	ICGC;COSMIC	22.404	Gain
CK1_CK1_CK1-D_CSNK1E_ST	Q13541	EIF4EBP1	P49674	CSNK1E	T10	C7S	7	Missense	distal	-3	no	19.923	23.197	EPSD	ICGC;COSMIC	22.404	Gain
CK1_CK1_CK1-D_CSNK1E_ST	Q13541	EIF4EBP1	P49674	CSNK1E	S12	C7S	7	Missense	distal	-5	no	21.605	23.167	EPSD	ICGC;COSMIC	22.404	Gain
CK1_CK1_CK1-D_CSNK1E_ST	Q13541	EIF4EBP1	P49674	CSNK1E	T41	G40V	40	Missense	proximal	-1	no	33.757	30.944	PhosphoSitePlus;EPSD	ICGC;COSMIC	22.404	Down-regulation
CK1_CK1_CK1-D_CSNK1E_ST	Q13541	EIF4EBP1	P49674	CSNK1E	T41	S35I	35	Missense	distal	-6	no	33.757	33.932	PhosphoSitePlus;EPSD	ICGC	22.404	Up-regulation
CK1_CK1_CK1-D_CSNK1E_ST	Q13541	EIF4EBP1	P49674	CSNK1E	T50	Y54N	54	Missense	distal	4	no	32.732	32.675	EPSD;PhosphoSitePlus	ICGC;COSMIC	22.404	Down-regulation
CK1_CK1_CK1-D_CSNK1E_ST	Q13541	EIF4EBP1	P49674	CSNK1E	S96	S94I	94	Missense	proximal	-2	no	33.148	32.359	EPSD	ICGC	22.404	Down-regulation
CK1_CK1_CK1-D_CSNK1E_ST	Q13541	EIF4EBP1	P49674	CSNK1E	S96	H97Q	97	Missense	proximal	1	no	33.148	32.329	EPSD	ICGC;COSMIC	22.404	Down-regulation
CK1_CK1_CK1-D_CSNK1E_ST	Q13541	EIF4EBP1	P49674	CSNK1E	S96	S101C	101	Missense	distal	5	no	33.148	34.254	EPSD	ICGC;COSMIC	22.404	Up-regulation
CK1_CK1_CK1-D_CSNK1E_ST	Q9BZL6	PRKD2	P49674	CSNK1E	S43	S46I	46	Missense	distal	3	no	22.985	18.987	EPSD	ICGC;COSMIC	22.404	Loss
CK1_CK1_CK1-D_CSNK1E_ST	Q9BZL6	PRKD2	P49674	CSNK1E	S43	S43Y	43	Missense	central	0	yes	22.985	0.000	EPSD	ICGC	22.404	Loss
CK1_CK1_CK1-D_CSNK1E_ST	Q9BZL6	PRKD2	P49674	CSNK1E	S43	H48Q	48	Missense	distal	5	no	22.985	22.028	EPSD	ICGC	22.404	Loss
CK1_CK1_CK1-D_CSNK1E_ST	Q9BZL6	PRKD2	P49674	CSNK1E	S43	S46T	46	Missense	distal	3	no	22.985	17.846	EPSD	ICGC;COSMIC	22.404	Loss
CK1_CK1_CK1-D_CSNK1E_ST	O60716	CTNND1	P49674	CSNK1E	S125	G119C	119	Missense	distal	-6	no	33.410	32.802	EPSD	ICGC	22.404	Down-regulation
CK1_CK1_CK1-D_CSNK1E_ST	O60716	CTNND1	P49674	CSNK1E	S125	S129I	129	Missense	distal	4	no	33.410	33.383	EPSD	ICGC	22.404	Down-regulation
CK1_CK1_CK1-D_CSNK1E_ST	O60353	FZD6	P49674	CSNK1E	S620	A623S	623	Missense	distal	3	no	21.632	27.793	EPSD	ICGC	22.404	Gain
CK1_CK1_CK1-D_CSNK1E_ST	O60353	FZD6	P49674	CSNK1E	S624	R627I	627	Missense	distal	3	no	31.668	29.714	EPSD	ICGC	22.404	Down-regulation
CK1_CK1_CK1-D_CSNK1E_ST	O60353	FZD6	P49674	CSNK1E	S624	A623S	623	Missense	proximal	-1	no	31.668	27.993	EPSD	ICGC	22.404	Down-regulation
CK1_CK1_CK1-D_CSNK1E_ST	O60353	FZD6	P49674	CSNK1E	S645	A646V	646	Missense	proximal	1	no	33.678	33.650	EPSD	ICGC;COSMIC;GDSC;CCLE	22.404	Down-regulation
CK1_CK1_CK1-D_CSNK1E_ST	O60353	FZD6	P49674	CSNK1E	S645	V642L	642	Missense	distal	-3	no	33.678	33.488	EPSD	ICGC	22.404	Down-regulation
CK1_CK1_CK1-D_CSNK1E_ST	O60353	FZD6	P49674	CSNK1E	S645	E649Q	649	Missense	distal	4	no	33.678	33.692	EPSD	ICGC;COSMIC	22.404	Up-regulation
CK1_CK1_CK1-D_CSNK1E_ST	O60353	FZD6	P49674	CSNK1E	S648	A646V	646	Missense	proximal	-2	no	22.685	20.699	PhosphoSitePlus	ICGC;COSMIC;GDSC;CCLE	22.404	Loss
CK1_CK1_CK1-D_CSNK1E_ST	O60353	FZD6	P49674	CSNK1E	S648	V642L	642	Missense	distal	-6	no	22.685	22.802	PhosphoSitePlus	ICGC	22.404	Up-regulation
CK1_CK1_CK1-D_CSNK1E_ST	O60353	FZD6	P49674	CSNK1E	S648	E649Q	649	Missense	proximal	1	no	22.685	22.197	PhosphoSitePlus	ICGC;COSMIC	22.404	Loss
CK1_CK1_CK1-D_CSNK1E_ST	O60353	FZD6	P49674	CSNK1E	S674	L669F	669	Missense	distal	-5	no	28.754	28.543	EPSD	ICGC;COSMIC	22.404	Down-regulation
CK1_CK1_CK1-D_CSNK1E_ST	O60353	FZD6	P49674	CSNK1E	S674	S678I	678	Missense	distal	4	no	28.754	28.728	EPSD	ICGC;COSMIC	22.404	Down-regulation
CK1_CK1_CK1-D_CSNK1E_ST	O60353	FZD6	P49674	CSNK1E	S675	L669F	669	Missense	distal	-6	no	22.598	22.729	EPSD	ICGC;COSMIC	22.404	Up-regulation
CK1_CK1_CK1-D_CSNK1E_ST	O60353	FZD6	P49674	CSNK1E	S675	S678I	678	Missense	distal	3	no	22.598	18.600	EPSD	ICGC;COSMIC	22.404	Loss
CAMK_CAMK1_CAMK1_ST	P46527	CDKN1B	Q14012	CAMK1	S106	V109G	109	Missense	distal	3	no	34.909	34.912	EPSD	ICGC;COSMIC	32.882	Up-regulation
CAMK_CAMK1_CAMK1_ST	P46527	CDKN1B	Q14012	CAMK1	S106	C99W	99	Missense	distal	-7	no	34.909	35.854	EPSD	ICGC;COSMIC	32.882	Up-regulation
CAMK_CAMK1_CAMK1_ST	P46527	CDKN1B	Q14012	CAMK1	S106	P102T	102	Missense	distal	-4	no	34.909	39.523	EPSD	ICGC;COSMIC	32.882	Up-regulation
CAMK_CAMK1_CAMK1_ST	P46527	CDKN1B	Q14012	CAMK1	T157	Q163E	163	Missense	distal	6	no	48.065	48.631	PhosphoSitePlus;EPSD	ICGC;COSMIC	32.882	Up-regulation
CAMK_CAMK1_CAMK1_ST	P46527	CDKN1B	Q14012	CAMK1	T157	S160F	160	Missense	distal	3	no	48.065	48.072	PhosphoSitePlus;EPSD	ICGC;COSMIC	32.882	Up-regulation
CAMK_CAMK1_CAMK1_ST	P46527	CDKN1B	Q14012	CAMK1	T157	T162I	162	Missense	distal	5	no	48.065	45.135	PhosphoSitePlus;EPSD	ICGC;COSMIC	32.882	Down-regulation
CAMK_CAMK1_CAMK1_ST	P46527	CDKN1B	Q14012	CAMK1	T170	Q163E	163	Missense	distal	-7	no	43.298	43.176	EPSD	ICGC;COSMIC	32.882	Down-regulation
CAMK_CAMK1_CAMK1_ST	P46527	CDKN1B	Q14012	CAMK1	T170	G177V	177	Missense	distal	7	no	43.298	43.355	EPSD	ICGC	32.882	Up-regulation
CAMK_CAMK1_CAMK1_ST	P46527	CDKN1B	Q14012	CAMK1	T198	G192V	192	Missense	distal	-6	no	47.865	45.826	EPSD;PhosphoSitePlus	ICGC	32.882	Down-regulation
CAMK_CAMK1_CAMK1_ST	P46527	CDKN1B	Q14012	CAMK1	T198	P191H	191	Missense	distal	-7	no	47.865	48.555	EPSD;PhosphoSitePlus	ICGC;COSMIC	32.882	Up-regulation
CAMK_CAMK1_CAMK1_ST	Q9NP62	GCM1	Q14012	CAMK1	S47	R54Q	54	Missense	distal	7	no	46.907	46.558	PhosphoSitePlus	ICGC;COSMIC	32.882	Down-regulation
CAMK_CAMK1_CAMK1_ST	Q9NP62	GCM1	Q14012	CAMK1	S47	A52V	52	Missense	distal	5	no	46.907	46.767	PhosphoSitePlus	ICGC;COSMIC	32.882	Down-regulation
CAMK_CAMK1_CAMK1_ST	Q9NP62	GCM1	Q14012	CAMK1	S47	D49E	49	Missense	proximal	2	no	46.907	46.778	PhosphoSitePlus	ICGC	32.882	Down-regulation
CAMK_CAMK1_CAMK1_ST	Q9NP62	GCM1	Q14012	CAMK1	S47	E48K	48	Missense	proximal	1	no	46.907	39.879	PhosphoSitePlus	ICGC	32.882	Down-regulation
CAMK_CAMK1_CAMK1_ST	Q9NP62	GCM1	Q14012	CAMK1	T174	A175E	175	Missense	proximal	1	no	42.288	45.341	EPSD	ICGC	32.882	Up-regulation
CAMK_CAMK1_CAMK1_ST	Q9NP62	GCM1	Q14012	CAMK1	T174	A175S	175	Missense	proximal	1	no	42.288	42.506	EPSD	ICGC	32.882	Up-regulation
CAMK_CAMK1_CAMK1_ST	O43432	EIF4G3	Q14012	CAMK1	T168	P167S	167	Missense	proximal	-1	no	36.626	36.633	EPSD	ICGC	32.882	Up-regulation
CAMK_CAMK1_CAMK1_ST	O43432	EIF4G3	Q14012	CAMK1	T168	P170S	170	Missense	proximal	2	no	36.626	37.766	EPSD	ICGC	32.882	Up-regulation
CAMK_CAMK1_CAMK1_ST	O43432	EIF4G3	Q14012	CAMK1	T168	G172E	172	Missense	distal	4	no	36.626	36.014	EPSD	ICGC;COSMIC	32.882	Down-regulation
CAMK_CAMK1_CAMK1_ST	O43432	EIF4G3	Q14012	CAMK1	T168	T168A	168	Missense	central	0	yes	36.626	0.000	EPSD	ICGC;COSMIC	32.882	Loss
CAMK_CAMK1_CAMK1_ST	O43432	EIF4G3	Q14012	CAMK1	S176	Q182K	182	Missense	distal	6	no	37.890	37.829	EPSD	ICGC;COSMIC	32.882	Down-regulation
CAMK_CAMK1_CAMK1_ST	O43432	EIF4G3	Q14012	CAMK1	S176	P170S	170	Missense	distal	-6	no	37.890	38.606	EPSD	ICGC	32.882	Up-regulation
CAMK_CAMK1_CAMK1_ST	O43432	EIF4G3	Q14012	CAMK1	S176	G172E	172	Missense	distal	-4	no	37.890	39.220	EPSD	ICGC;COSMIC	32.882	Up-regulation
CAMK_CAMK1_CAMK1_ST	O43432	EIF4G3	Q14012	CAMK1	S719	E722D	722	Missense	distal	3	no	33.860	33.877	EPSD	ICGC;COSMIC	32.882	Up-regulation
CAMK_CAMK1_CAMK1_ST	O43432	EIF4G3	Q14012	CAMK1	S719	K714T	714	Missense	distal	-5	no	33.860	35.015	EPSD	ICGC;COSMIC	32.882	Up-regulation
CAMK_CAMK1_CAMK1_ST	O43432	EIF4G3	Q14012	CAMK1	S866	R873S	873	Missense	distal	7	no	38.565	38.502	EPSD	ICGC;COSMIC	32.882	Down-regulation
CAMK_CAMK1_CAMK1_ST	P24844	MYL9	Q14012	CAMK1	T11	R17L	17	Missense	distal	6	no	34.276	33.702	EPSD	ICGC;COSMIC	32.882	Down-regulation
CAMK_CAMK1_CAMK1_ST	P24844	MYL9	Q14012	CAMK1	T11	R5Q	5	Missense	distal	-6	no	34.276	32.832	EPSD	ICGC;COSMIC	32.882	Loss
CAMK_CAMK1_CAMK1_ST	P24844	MYL9	Q14012	CAMK1	T11	R14W	14	Missense	distal	3	no	34.276	34.296	EPSD	ICGC;COSMIC	32.882	Up-regulation
CAMK_CAMK1_CAMK1_ST	P24844	MYL9	Q14012	CAMK1	T19	R17L	17	Missense	proximal	-2	no	41.883	37.862	EPSD	ICGC;COSMIC	32.882	Down-regulation
CAMK_CAMK1_CAMK1_ST	P24844	MYL9	Q14012	CAMK1	T19	R14W	14	Missense	distal	-5	no	41.883	36.126	EPSD	ICGC;COSMIC	32.882	Down-regulation
CAMK_CAMK1_CAMK1_ST	P24844	MYL9	Q14012	CAMK1	S20	R17L	17	Missense	distal	-3	no	50.791	36.343	PhosphoSitePlus	ICGC;COSMIC	32.882	Down-regulation
CAMK_CAMK1_CAMK1_ST	P24844	MYL9	Q14012	CAMK1	S20	R14W	14	Missense	distal	-6	no	50.791	49.110	PhosphoSitePlus	ICGC;COSMIC	32.882	Down-regulation
CAMK_CAMK1_CAMK1_ST	P24844	MYL9	Q14012	CAMK1	T128	F134L	134	Missense	distal	6	no	39.643	39.959	EPSD	ICGC;COSMIC	32.882	Up-regulation
CAMK_CAMK1_CAMK1_ST	Q05469	LIPE	Q14012	CAMK1	S565	A558V	558	Missense	distal	-7	no	38.493	38.530	EPSD	ICGC;COSMIC	32.882	Up-regulation
CAMK_CAMK1_CAMK1_ST	Q05469	LIPE	Q14012	CAMK1	S565	R563M	563	Missense	proximal	-2	no	38.493	32.935	EPSD	ICGC;COSMIC	32.882	Down-regulation
CAMK_CAMK1_CAMK1_ST	Q05469	LIPE	Q14012	CAMK1	S607	R611C	611	Missense	distal	4	no	34.844	35.502	EPSD	ICGC	32.882	Up-regulation
CAMK_CAMK1_CAMK1_ST	Q05469	LIPE	Q14012	CAMK1	S607	P600H	600	Missense	distal	-7	no	34.844	35.533	EPSD	ICGC;COSMIC	32.882	Up-regulation
CAMK_CAMK1_CAMK1_ST	Q05469	LIPE	Q14012	CAMK1	T813	R810W	810	Missense	distal	-3	no	43.057	26.995	EPSD	ICGC;COSMIC	32.882	Loss
CAMK_CAMK1_CAMK1_ST	Q05469	LIPE	Q14012	CAMK1	T813	V809L	809	Missense	distal	-4	no	43.057	42.455	EPSD	ICGC;COSMIC	32.882	Down-regulation
CAMK_CAMK1_CAMK1_ST	Q05469	LIPE	Q14012	CAMK1	S855	R852H	852	Missense	distal	-3	no	51.500	44.273	PhosphoSitePlus	ICGC;COSMIC	32.882	Down-regulation
CAMK_CAMK1_CAMK1_ST	Q9UQM7	CAMK2A	Q14012	CAMK1	S78	V73I	73	Missense	distal	-5	no	32.651	35.403	EPSD	ICGC;GDSC	32.882	Gain
CAMK_CAMK1_CAMK1_ST	Q9UQM7	CAMK2A	Q14012	CAMK1	S78	L75I	75	Missense	distal	-3	no	32.651	36.782	EPSD	ICGC;COSMIC	32.882	Gain
CAMK_CAMK1_CAMK1_ST	Q9UQM7	CAMK2A	Q14012	CAMK1	T261	N255I	255	Missense	distal	-6	no	37.406	38.559	EPSD	ICGC;COSMIC	32.882	Up-regulation
CAMK_CAMK1_CAMK1_ST	Q9UQM7	CAMK2A	Q14012	CAMK1	T261	N255Y	255	Missense	distal	-6	no	37.406	37.782	EPSD	ICGC;COSMIC	32.882	Up-regulation
CAMK_CAMK1_CAMK1_ST	Q9UQM7	CAMK2A	Q14012	CAMK1	T261	E264K	264	Missense	distal	3	no	37.406	37.429	EPSD	ICGC	32.882	Up-regulation
CAMK_CAMK1_CAMK1_ST	Q9UQM7	CAMK2A	Q14012	CAMK1	T276	R274H	274	Missense	proximal	-2	no	40.965	35.511	EPSD	ICGC	32.882	Down-regulation
CAMK_CAMK1_CAMK1_ST	Q9UQM7	CAMK2A	Q14012	CAMK1	T286	Q284K	284	Missense	proximal	-2	no	42.306	43.162	EPSD	ICGC	32.882	Up-regulation
CAMK_CAMK1_CAMK1_ST	Q9UQM7	CAMK2A	Q14012	CAMK1	T286	Q284H	284	Missense	proximal	-2	no	42.306	37.979	EPSD	ICGC;COSMIC	32.882	Down-regulation
CAMK_CAMK1_CAMK1_ST	Q9UQM7	CAMK2A	Q14012	CAMK1	T286	L290Q	290	Missense	distal	4	no	42.306	42.749	EPSD	ICGC;COSMIC	32.882	Up-regulation
CAMK_CAMK1_CAMK1_ST	Q9UQM7	CAMK2A	Q14012	CAMK1	T286	T286I	286	Missense	central	0	yes	42.306	0.000	EPSD	ICGC;COSMIC	32.882	Loss
CAMK_CAMK1_CAMK1_ST	Q9UQM7	CAMK2A	Q14012	CAMK1	S314	G315R	315	Missense	proximal	1	no	40.259	43.653	EPSD	ICGC;COSMIC	32.882	Up-regulation
CAMK_CAMK1_CAMK1_ST	Q9UQM7	CAMK2A	Q14012	CAMK1	S314	R311M	311	Missense	distal	-3	no	40.259	13.684	EPSD	ICGC;COSMIC	32.882	Loss
CAMK_CAMK1_CAMK1_ST	Q9UQM7	CAMK2A	Q14012	CAMK1	S318	G315R	315	Missense	distal	-3	no	17.928	42.620	EPSD	ICGC;COSMIC	32.882	Gain
CAMK_CAMK1_CAMK1_ST	Q9UQM7	CAMK2A	Q14012	CAMK1	S331	S331L	331	Missense	central	0	yes	40.579	0.000	EPSD	ICGC;COSMIC	32.882	Loss
CAMK_CAMK1_CAMK1_ST	Q9UQM7	CAMK2A	Q14012	CAMK1	S331	S324I	324	Missense	distal	-7	no	40.579	40.760	EPSD	ICGC	32.882	Up-regulation
CAMK_CAMK1_CAMK1_ST	Q9Y570	PPME1	Q14012	CAMK1	S15	P18S	18	Missense	distal	3	no	50.189	50.190	PhosphoSitePlus	ICGC;COSMIC	32.882	Up-regulation
CAMK_CAMK1_CAMK1_ST	Q9Y570	PPME1	Q14012	CAMK1	S15	R12L	12	Missense	distal	-3	no	50.189	35.742	PhosphoSitePlus	ICGC	32.882	Down-regulation
CAMK_CAMK1_CAMK1_ST	Q9Y570	PPME1	Q14012	CAMK1	S15	R16L	16	Missense	proximal	1	no	50.189	48.916	PhosphoSitePlus	ICGC	32.882	Down-regulation
CAMK_CAMK1_CAMK1_ST	Q9Y570	PPME1	Q14012	CAMK1	S15	S15Y	15	Missense	central	0	yes	50.189	0.000	PhosphoSitePlus	ICGC;COSMIC	32.882	Loss
CAMK_CAMK1_CAMK1_ST	Q9Y570	PPME1	Q14012	CAMK1	S265	E258D	258	Missense	distal	-7	no	33.108	32.749	EPSD	ICGC	32.882	Loss
CAMK_CAMK1_CAMK1_ST	Q9Y570	PPME1	Q14012	CAMK1	S265	D261Y	261	Missense	distal	-4	no	33.108	34.920	EPSD	ICGC	32.882	Up-regulation
CAMK_CAMK1_CAMK1_ST	Q9Y570	PPME1	Q14012	CAMK1	S265	S269I	269	Missense	distal	4	no	33.108	33.234	EPSD	ICGC	32.882	Up-regulation
CAMK_CAMK1_CAMK1_ST	P39019	RPS19	Q14012	CAMK1	S59	A61V	61	Missense	proximal	2	no	49.508	48.532	PhosphoSitePlus	ICGC;COSMIC	32.882	Down-regulation
CAMK_CAMK1_CAMK1_ST	P39019	RPS19	Q14012	CAMK1	S59	A61G	61	Missense	proximal	2	no	49.508	48.760	PhosphoSitePlus	ICGC;COSMIC	32.882	Down-regulation
CAMK_CAMK1_CAMK1_ST	Q9UKV0	HDAC9	Q14012	CAMK1	T141	S140F	140	Missense	proximal	-1	no	36.021	35.973	EPSD	ICGC;COSMIC	32.882	Down-regulation
CAMK_CAMK1_CAMK1_ST	Q9UKV0	HDAC9	Q14012	CAMK1	S240	S240N	240	Missense	central	0	yes	36.517	0.000	EPSD	ICGC	32.882	Loss
CAMK_CAMK1_CAMK1_ST	Q9UKV0	HDAC9	Q14012	CAMK1	S607	P613S	613	Missense	distal	6	no	38.783	39.312	EPSD	ICGC;COSMIC;CCLE	32.882	Up-regulation
CAMK_CAMK1_CAMK1_ST	Q9UKV0	HDAC9	Q14012	CAMK1	S607	E601G	601	Missense	distal	-6	no	38.783	41.035	EPSD	ICGC;COSMIC	32.882	Up-regulation
CAMK_CAMK1_CAMK1_ST	Q9UKV0	HDAC9	Q14012	CAMK1	S607	S612F	612	Missense	distal	5	no	38.783	36.166	EPSD	ICGC;COSMIC	32.882	Down-regulation
CAMK_CAMK1_CAMK1_ST	Q9UKV0	HDAC9	Q14012	CAMK1	S607	A614T	614	Missense	distal	7	no	38.783	37.271	EPSD	ICGC;COSMIC	32.882	Down-regulation
CAMK_CAMK1_CAMK1_ST	Q9UKV0	HDAC9	Q14012	CAMK1	S607	R604H	604	Missense	distal	-3	no	38.783	31.555	EPSD	ICGC;COSMIC	32.882	Loss
CAMK_CAMK1_CAMK1_ST	Q9UKV0	HDAC9	Q14012	CAMK1	S607	T609S	609	Missense	proximal	2	no	38.783	39.990	EPSD	ICGC	32.882	Up-regulation
CAMK_CAMK1_CAMK1_ST	Q9UKV0	HDAC9	Q14012	CAMK1	S611	P613S	613	Missense	proximal	2	no	38.514	39.653	EPSD	ICGC;COSMIC;CCLE	32.882	Up-regulation
CAMK_CAMK1_CAMK1_ST	Q9UKV0	HDAC9	Q14012	CAMK1	S611	S612F	612	Missense	proximal	1	no	38.514	37.781	EPSD	ICGC;COSMIC	32.882	Down-regulation
CAMK_CAMK1_CAMK1_ST	Q9UKV0	HDAC9	Q14012	CAMK1	S611	A614T	614	Missense	distal	3	no	38.514	38.508	EPSD	ICGC;COSMIC	32.882	Down-regulation
CAMK_CAMK1_CAMK1_ST	Q9UKV0	HDAC9	Q14012	CAMK1	S611	R604H	604	Missense	distal	-7	no	38.514	37.866	EPSD	ICGC;COSMIC	32.882	Down-regulation
CAMK_CAMK1_CAMK1_ST	Q9UKV0	HDAC9	Q14012	CAMK1	S611	T609S	609	Missense	proximal	-2	no	38.514	34.820	EPSD	ICGC	32.882	Down-regulation
CAMK_CAMK1_CAMK1_ST	Q9UKV0	HDAC9	Q14012	CAMK1	S767	E760G	760	Missense	distal	-7	no	37.250	36.436	EPSD	ICGC;COSMIC	32.882	Down-regulation
CAMK_CAMK1_CAMK1_ST	Q9UKV0	HDAC9	Q14012	CAMK1	S767	V765M	765	Missense	proximal	-2	no	37.250	37.700	EPSD	ICGC	32.882	Up-regulation
CAMK_CAMK1_CAMK1_ST	Q9UKV0	HDAC9	Q14012	CAMK1	S767	E760K	760	Missense	distal	-7	no	37.250	36.917	EPSD	ICGC	32.882	Down-regulation
CAMK_CAMK1_CAMK1_ST	Q9UKV0	HDAC9	Q14012	CAMK1	S767	N772D	772	Missense	distal	5	no	37.250	35.008	EPSD	ICGC	32.882	Down-regulation
CAMK_CAMK1_CAMK1_ST	Q9UKV0	HDAC9	Q14012	CAMK1	S996	Q998L	998	Missense	proximal	2	no	33.453	34.006	EPSD	ICGC	32.882	Up-regulation
CAMK_CAMK1_CAMK1_ST	Q9UKV0	HDAC9	Q14012	CAMK1	S996	P989S	989	Missense	distal	-7	no	33.453	34.167	EPSD	ICGC	32.882	Up-regulation
CAMK_CAMK1_CAMK1_ST	Q9UKV0	HDAC9	Q14012	CAMK1	S996	Q998H	998	Missense	proximal	2	no	33.453	34.952	EPSD	ICGC;COSMIC	32.882	Up-regulation
CAMK_CAMK1_CAMK1_ST	Q9UKV0	HDAC9	Q14012	CAMK1	S996	M991I	991	Missense	distal	-5	no	33.453	35.174	EPSD	ICGC;COSMIC	32.882	Up-regulation
TK_Src_SrcA_YES1_Y	P09917	ALOX5	P07947	YES1	Y23	Y21H	21	Missense	proximal	-2	no	24.000	23.978	PhosphoSitePlus;EPSD	ICGC;COSMIC	16.372	Down-regulation
TK_Src_SrcA_YES1_Y	P09917	ALOX5	P07947	YES1	Y23	S29L	29	Missense	distal	6	no	24.000	22.508	PhosphoSitePlus;EPSD	ICGC	16.372	Down-regulation
TK_Src_SrcA_YES1_Y	P09917	ALOX5	P07947	YES1	Y446	D443E	443	Missense	distal	-3	no	20.656	15.324	EPSD;PhosphoSitePlus	ICGC;COSMIC	16.372	Loss
TK_Src_SrcA_YES1_Y	P09917	ALOX5	P07947	YES1	Y446	A447D	447	Missense	proximal	1	no	20.656	19.519	EPSD;PhosphoSitePlus	ICGC;COSMIC	16.372	Down-regulation
TK_Src_SrcA_YES1_Y	P09917	ALOX5	P07947	YES1	Y446	R439M	439	Missense	distal	-7	no	20.656	20.612	EPSD;PhosphoSitePlus	ICGC	16.372	Down-regulation
TK_Src_SrcA_YES1_Y	P09917	ALOX5	P07947	YES1	Y446	C450G	450	Missense	distal	4	no	20.656	20.696	EPSD;PhosphoSitePlus	ICGC	16.372	Up-regulation
TK_Src_SrcA_YES1_Y	Q05397	PTK2	P07947	YES1	Y861	P854L	854	Missense	distal	-7	no	28.135	28.092	EPSD;PhosphoSitePlus	ICGC;COSMIC	16.372	Down-regulation
TK_Src_SrcA_YES1_Y	Q05397	PTK2	P07947	YES1	Y861	H859Y	859	Missense	proximal	-2	no	28.135	28.158	EPSD;PhosphoSitePlus	ICGC;COSMIC	16.372	Up-regulation
TK_Src_SrcA_YES1_Y	P04626	ERBB2	P07947	YES1	Y923	A928S	928	Missense	distal	5	no	19.455	18.299	EPSD	ICGC	16.372	Down-regulation
TK_Src_SrcA_YES1_Y	P46527	CDKN1B	P07947	YES1	Y74	V79L	79	Missense	distal	5	no	31.675	30.445	EPSD;PhosphoSitePlus	ICGC;COSMIC	16.372	Down-regulation
TK_Src_SrcA_YES1_Y	P46527	CDKN1B	P07947	YES1	Y74	E78K	78	Missense	distal	4	no	31.675	31.597	EPSD;PhosphoSitePlus	ICGC;COSMIC	16.372	Down-regulation
TK_Src_SrcA_YES1_Y	P46527	CDKN1B	P07947	YES1	Y88	Y89H	89	Missense	proximal	1	no	30.194	28.698	EPSD;PhosphoSitePlus	ICGC;COSMIC	16.372	Down-regulation
TK_Src_SrcA_YES1_Y	P46527	CDKN1B	P07947	YES1	Y89	Y89H	89	Missense	central	0	yes	28.772	0.000	PhosphoSitePlus;EPSD	ICGC;COSMIC	16.372	Loss
TK_Src_SrcA_YES1_Y	P14921	ETS1	P07947	YES1	Y283	P281Q	281	Missense	proximal	-2	no	22.413	22.434	PhosphoSitePlus	ICGC	16.372	Up-regulation
TK_Src_SrcA_YES1_Y	Q16543	CDC37	P07947	YES1	Y298	E299V	299	Missense	proximal	1	no	29.701	25.533	PhosphoSitePlus	ICGC;COSMIC	16.372	Down-regulation
TK_Src_SrcA_YES1_Y	P11802	CDK4	P07947	YES1	Y17	G15C	15	Missense	proximal	-2	no	28.759	28.746	PhosphoSitePlus	ICGC;COSMIC	16.372	Down-regulation
Other_IKK_TBK1_ST	Q96FA3	PELI1	Q9UHD2	TBK1	S76	S70C	70	Missense	distal	-6	no	180.586	167.736	EPSD;PhosphoSitePlus	ICGC	145.681	Down-regulation
Other_IKK_TBK1_ST	Q96FA3	PELI1	Q9UHD2	TBK1	S76	R83Q	83	Missense	distal	7	no	180.586	180.561	EPSD;PhosphoSitePlus	ICGC;COSMIC	145.681	Down-regulation
Other_IKK_TBK1_ST	Q96FA3	PELI1	Q9UHD2	TBK1	S76	Q74K	74	Missense	proximal	-2	no	180.586	179.391	EPSD;PhosphoSitePlus	ICGC;COSMIC	145.681	Down-regulation
Other_IKK_TBK1_ST	Q96FA3	PELI1	Q9UHD2	TBK1	S76	N71K	71	Missense	distal	-5	no	180.586	181.049	EPSD;PhosphoSitePlus	ICGC	145.681	Up-regulation
Other_IKK_TBK1_ST	Q96FA3	PELI1	Q9UHD2	TBK1	S76	H75Y	75	Missense	proximal	-1	no	180.586	179.668	EPSD;PhosphoSitePlus	ICGC;COSMIC	145.681	Down-regulation
Other_IKK_TBK1_ST	Q96FA3	PELI1	Q9UHD2	TBK1	T80	R83Q	83	Missense	distal	3	no	178.443	178.100	PhosphoSitePlus;EPSD	ICGC;COSMIC	145.681	Down-regulation
Other_IKK_TBK1_ST	Q96FA3	PELI1	Q9UHD2	TBK1	T80	Q74K	74	Missense	distal	-6	no	178.443	163.164	PhosphoSitePlus;EPSD	ICGC;COSMIC	145.681	Down-regulation
Other_IKK_TBK1_ST	Q96FA3	PELI1	Q9UHD2	TBK1	T80	H75Y	75	Missense	distal	-5	no	178.443	179.120	PhosphoSitePlus;EPSD	ICGC;COSMIC	145.681	Up-regulation
Other_IKK_TBK1_ST	Q96FA3	PELI1	Q9UHD2	TBK1	S82	R83Q	83	Missense	proximal	1	no	154.905	138.553	EPSD	ICGC;COSMIC	145.681	Loss
Other_IKK_TBK1_ST	Q96FA3	PELI1	Q9UHD2	TBK1	S82	H75Y	75	Missense	distal	-7	no	154.905	154.830	EPSD	ICGC;COSMIC	145.681	Down-regulation
Other_IKK_TBK1_ST	Q96FA3	PELI1	Q9UHD2	TBK1	S125	T127A	127	Missense	proximal	2	no	148.101	146.432	EPSD	ICGC;COSMIC	145.681	Down-regulation
Other_IKK_TBK1_ST	Q96FA3	PELI1	Q9UHD2	TBK1	T288	N287D	287	Missense	proximal	-1	no	175.899	174.590	EPSD;PhosphoSitePlus	ICGC;COSMIC	145.681	Down-regulation
Other_IKK_TBK1_ST	Q96FA3	PELI1	Q9UHD2	TBK1	S293	N287D	287	Missense	distal	-6	no	183.079	187.232	EPSD;PhosphoSitePlus	ICGC;COSMIC	145.681	Up-regulation
Other_IKK_TBK1_ST	Q13501	SQSTM1	Q9UHD2	TBK1	S182	R186Q	186	Missense	distal	4	no	146.626	146.729	EPSD	ICGC;COSMIC	145.681	Up-regulation
Other_IKK_TBK1_ST	Q13501	SQSTM1	Q9UHD2	TBK1	S182	R183P	183	Missense	proximal	1	no	146.626	146.751	EPSD	ICGC;COSMIC	145.681	Up-regulation
Other_IKK_TBK1_ST	Q13501	SQSTM1	Q9UHD2	TBK1	S182	V188L	188	Missense	distal	6	no	146.626	141.037	EPSD	ICGC;COSMIC	145.681	Loss
Other_IKK_TBK1_ST	Q13501	SQSTM1	Q9UHD2	TBK1	S229	P232L	232	Missense	distal	3	no	146.836	145.951	EPSD	ICGC;COSMIC	145.681	Down-regulation
Other_IKK_TBK1_ST	Q13501	SQSTM1	Q9UHD2	TBK1	S229	S233I	233	Missense	distal	4	no	146.836	140.279	EPSD	ICGC	145.681	Loss
Other_IKK_TBK1_ST	Q13501	SQSTM1	Q9UHD2	TBK1	S283	S284L	284	Missense	proximal	1	no	143.535	158.938	EPSD	ICGC;COSMIC	145.681	Gain
Other_IKK_TBK1_ST	Q96CV9	OPTN	Q9UHD2	TBK1	S162	V161L	161	Missense	proximal	-1	no	148.195	148.089	EPSD	ICGC	145.681	Down-regulation
Other_IKK_TBK1_ST	Q96CV9	OPTN	Q9UHD2	TBK1	S177	E175K	175	Missense	proximal	-2	no	192.197	191.261	PhosphoSitePlus;EPSD	ICGC	145.681	Down-regulation
Other_IKK_TBK1_ST	Q96CV9	OPTN	Q9UHD2	TBK1	T204	V205F	205	Missense	proximal	1	no	125.022	155.747	EPSD	ICGC	145.681	Gain
Other_IKK_TBK1_ST	Q96CV9	OPTN	Q9UHD2	TBK1	S308	L304I	304	Missense	distal	-4	no	145.900	144.972	EPSD	ICGC;COSMIC	145.681	Loss
Other_IKK_TBK1_ST	Q96CV9	OPTN	Q9UHD2	TBK1	S308	Q305K	305	Missense	distal	-3	no	145.900	138.819	EPSD	ICGC;COSMIC	145.681	Loss
Other_IKK_TBK1_ST	Q96CV9	OPTN	Q9UHD2	TBK1	S367	S370L	370	Missense	distal	3	no	146.093	146.858	EPSD	ICGC;COSMIC	145.681	Up-regulation
Other_IKK_TBK1_ST	Q96CV9	OPTN	Q9UHD2	TBK1	S367	V365L	365	Missense	proximal	-2	no	146.093	147.856	EPSD	ICGC	145.681	Up-regulation
Other_IKK_TBK1_ST	Q96CV9	OPTN	Q9UHD2	TBK1	S473	H476R	476	Missense	distal	3	no	174.328	173.946	EPSD;PhosphoSitePlus	ICGC;COSMIC	145.681	Down-regulation
Other_IKK_TBK1_ST	Q96CV9	OPTN	Q9UHD2	TBK1	S473	A480E	480	Missense	distal	7	no	174.328	174.329	EPSD;PhosphoSitePlus	ICGC;COSMIC	145.681	Up-regulation
Other_IKK_TBK1_ST	Q96CV9	OPTN	Q9UHD2	TBK1	S473	D474Y	474	Missense	proximal	1	no	174.328	191.491	EPSD;PhosphoSitePlus	ICGC	145.681	Up-regulation
Other_IKK_TBK1_ST	Q96CV9	OPTN	Q9UHD2	TBK1	S473	E469K	469	Missense	distal	-4	no	174.328	173.536	EPSD;PhosphoSitePlus	ICGC	145.681	Down-regulation
Other_IKK_TBK1_ST	Q96CV9	OPTN	Q9UHD2	TBK1	S513	R511S	511	Missense	proximal	-2	no	179.077	179.956	EPSD;PhosphoSitePlus	ICGC;COSMIC	145.681	Up-regulation
Other_IKK_TBK1_ST	Q96CV9	OPTN	Q9UHD2	TBK1	S513	R520C	520	Missense	distal	7	no	179.077	179.119	EPSD;PhosphoSitePlus	ICGC	145.681	Up-regulation
Other_IKK_TBK1_ST	Q96CV9	OPTN	Q9UHD2	TBK1	S519	A523V	523	Missense	distal	4	no	150.700	151.470	EPSD	ICGC;COSMIC	145.681	Up-regulation
Other_IKK_TBK1_ST	Q96CV9	OPTN	Q9UHD2	TBK1	S519	G522V	522	Missense	distal	3	no	150.700	150.427	EPSD	ICGC	145.681	Down-regulation
Other_IKK_TBK1_ST	Q96CV9	OPTN	Q9UHD2	TBK1	S519	R520C	520	Missense	proximal	1	no	150.700	112.680	EPSD	ICGC	145.681	Loss
Other_IKK_TBK1_ST	P23443	RPS6KB1	Q9UHD2	TBK1	T444	P445T	445	Missense	proximal	1	no	169.595	129.370	EPSD;PhosphoSitePlus	ICGC;COSMIC	145.681	Loss
Other_IKK_TBK1_ST	P23443	RPS6KB1	Q9UHD2	TBK1	T444	S441N	441	Missense	distal	-3	no	169.595	160.875	EPSD;PhosphoSitePlus	ICGC;COSMIC	145.681	Down-regulation
Other_IKK_TBK1_ST	P23443	RPS6KB1	Q9UHD2	TBK1	S447	P445T	445	Missense	proximal	-2	no	187.584	188.061	PhosphoSitePlus;EPSD	ICGC;COSMIC	145.681	Up-regulation
Other_IKK_TBK1_ST	P23443	RPS6KB1	Q9UHD2	TBK1	S447	S441N	441	Missense	distal	-6	no	187.584	179.164	PhosphoSitePlus;EPSD	ICGC;COSMIC	145.681	Down-regulation
Other_IKK_TBK1_ST	Q8TEV9	SMCR8	Q9UHD2	TBK1	S402	D396E	396	Missense	distal	-6	no	173.904	167.292	EPSD;PhosphoSitePlus	ICGC;COSMIC	145.681	Down-regulation
Other_IKK_TBK1_ST	Q8TEV9	SMCR8	Q9UHD2	TBK1	S414	V415F	415	Missense	proximal	1	no	123.094	153.819	EPSD	ICGC	145.681	Gain
Other_IKK_TBK1_ST	Q8TEV9	SMCR8	Q9UHD2	TBK1	S417	V415F	415	Missense	proximal	-2	no	147.876	148.424	EPSD	ICGC	145.681	Up-regulation
Other_IKK_TBK1_ST	Q8TEV9	SMCR8	Q9UHD2	TBK1	S465	G469C	469	Missense	distal	4	no	149.808	152.144	EPSD	ICGC;COSMIC	145.681	Up-regulation
Other_IKK_TBK1_ST	Q8TEV9	SMCR8	Q9UHD2	TBK1	S465	E470K	470	Missense	distal	5	no	149.808	148.831	EPSD	ICGC;COSMIC	145.681	Down-regulation
Other_IKK_TBK1_ST	Q8TEV9	SMCR8	Q9UHD2	TBK1	S465	I466F	466	Missense	proximal	1	no	149.808	158.597	EPSD	ICGC	145.681	Up-regulation
Other_IKK_TBK1_ST	Q8TEV9	SMCR8	Q9UHD2	TBK1	S465	D459N	459	Missense	distal	-6	no	149.808	145.655	EPSD	ICGC	145.681	Loss
Other_IKK_TBK1_ST	Q8TEV9	SMCR8	Q9UHD2	TBK1	S467	G469C	469	Missense	proximal	2	no	160.327	161.580	EPSD	ICGC;COSMIC	145.681	Up-regulation
Other_IKK_TBK1_ST	Q8TEV9	SMCR8	Q9UHD2	TBK1	S467	E470K	470	Missense	distal	3	no	160.327	160.826	EPSD	ICGC;COSMIC	145.681	Up-regulation
Other_IKK_TBK1_ST	Q8TEV9	SMCR8	Q9UHD2	TBK1	S467	I466F	466	Missense	proximal	-1	no	160.327	161.304	EPSD	ICGC	145.681	Up-regulation
Other_IKK_TBK1_ST	Q8TEV9	SMCR8	Q9UHD2	TBK1	S471	G469C	469	Missense	proximal	-2	no	165.570	164.862	EPSD	ICGC;COSMIC	145.681	Down-regulation
Other_IKK_TBK1_ST	Q8TEV9	SMCR8	Q9UHD2	TBK1	S471	L475F	475	Missense	distal	4	no	165.570	157.744	EPSD	ICGC	145.681	Down-regulation
Other_IKK_TBK1_ST	Q8TEV9	SMCR8	Q9UHD2	TBK1	S471	E470K	470	Missense	proximal	-1	no	165.570	166.431	EPSD	ICGC;COSMIC	145.681	Up-regulation
Other_IKK_TBK1_ST	Q8TEV9	SMCR8	Q9UHD2	TBK1	S471	I466F	466	Missense	distal	-5	no	165.570	164.974	EPSD	ICGC	145.681	Down-regulation
Other_IKK_TBK1_ST	Q8TEV9	SMCR8	Q9UHD2	TBK1	T511	E514K	514	Missense	distal	3	no	147.255	147.754	EPSD	ICGC;COSMIC	145.681	Up-regulation
Other_IKK_TBK1_ST	Q8TEV9	SMCR8	Q9UHD2	TBK1	T511	T511A	511	Missense	central	0	yes	147.255	0.000	EPSD	ICGC	145.681	Loss
Other_IKK_TBK1_ST	Q8TEV9	SMCR8	Q9UHD2	TBK1	S513	E514K	514	Missense	proximal	1	no	146.784	134.442	EPSD	ICGC;COSMIC	145.681	Loss
Other_IKK_TBK1_ST	Q8TEV9	SMCR8	Q9UHD2	TBK1	S513	T511A	511	Missense	proximal	-2	no	146.784	146.395	EPSD	ICGC	145.681	Down-regulation
Other_IKK_TBK1_ST	Q8TEV9	SMCR8	Q9UHD2	TBK1	S516	E514K	514	Missense	proximal	-2	no	159.533	158.597	EPSD	ICGC;COSMIC	145.681	Down-regulation
Other_IKK_TBK1_ST	Q8TEV9	SMCR8	Q9UHD2	TBK1	S516	T511A	511	Missense	distal	-5	no	159.533	159.541	EPSD	ICGC	145.681	Up-regulation
Other_IKK_TBK1_ST	Q8TEV9	SMCR8	Q9UHD2	TBK1	S667	S664T	664	Missense	distal	-3	no	146.772	142.678	EPSD	ICGC;COSMIC	145.681	Loss
Other_IKK_TBK1_ST	Q8TEV9	SMCR8	Q9UHD2	TBK1	S686	P690S	690	Missense	distal	4	no	141.254	147.476	EPSD	ICGC	145.681	Gain
Other_IKK_TBK1_ST	Q8TEV9	SMCR8	Q9UHD2	TBK1	S698	R705G	705	Missense	distal	7	no	158.080	158.077	EPSD	ICGC;COSMIC	145.681	Down-regulation
Other_IKK_TBK1_ST	Q8TEV9	SMCR8	Q9UHD2	TBK1	T796	G795S	795	Missense	proximal	-1	no	176.896	175.667	PhosphoSitePlus;EPSD	ICGC;COSMIC	145.681	Down-regulation
Other_IKK_TBK1_ST	Q8TEV9	SMCR8	Q9UHD2	TBK1	T796	G795C	795	Missense	proximal	-1	no	176.896	177.093	PhosphoSitePlus;EPSD	ICGC;COSMIC	145.681	Up-regulation
Other_IKK_TBK1_ST	Q8TEV9	SMCR8	Q9UHD2	TBK1	S886	K889N	889	Missense	distal	3	no	162.049	161.619	EPSD	ICGC;COSMIC	145.681	Down-regulation
Other_IKK_TBK1_ST	Q92985	IRF7	Q9UHD2	TBK1	S471	S471F	471	Missense	central	0	yes	179.793	0.000	EPSD;PhosphoSitePlus	ICGC;COSMIC	145.681	Loss
Other_IKK_TBK1_ST	Q92985	IRF7	Q9UHD2	TBK1	S471	S475N	475	Missense	distal	4	no	179.793	173.594	EPSD;PhosphoSitePlus	ICGC;COSMIC	145.681	Down-regulation
Other_IKK_TBK1_ST	Q92985	IRF7	Q9UHD2	TBK1	S471	T465M	465	Missense	distal	-6	no	179.793	174.619	EPSD;PhosphoSitePlus	ICGC	145.681	Down-regulation
Other_IKK_TBK1_ST	Q92985	IRF7	Q9UHD2	TBK1	S472	S471F	471	Missense	proximal	-1	no	185.384	186.961	EPSD;PhosphoSitePlus	ICGC;COSMIC	145.681	Up-regulation
Other_IKK_TBK1_ST	Q92985	IRF7	Q9UHD2	TBK1	S472	S479R	479	Missense	distal	7	no	185.384	185.440	EPSD;PhosphoSitePlus	ICGC;COSMIC	145.681	Up-regulation
Other_IKK_TBK1_ST	Q92985	IRF7	Q9UHD2	TBK1	S472	S475N	475	Missense	distal	3	no	185.384	186.543	EPSD;PhosphoSitePlus	ICGC;COSMIC	145.681	Up-regulation
Other_IKK_TBK1_ST	Q92985	IRF7	Q9UHD2	TBK1	S472	T465M	465	Missense	distal	-7	no	185.384	185.249	EPSD;PhosphoSitePlus	ICGC	145.681	Down-regulation
Other_IKK_TBK1_ST	Q92985	IRF7	Q9UHD2	TBK1	S477	S471F	471	Missense	distal	-6	no	177.525	165.766	PhosphoSitePlus;EPSD	ICGC;COSMIC	145.681	Down-regulation
Other_IKK_TBK1_ST	Q92985	IRF7	Q9UHD2	TBK1	S477	C481R	481	Missense	distal	4	no	177.525	180.480	PhosphoSitePlus;EPSD	ICGC;COSMIC	145.681	Up-regulation
Other_IKK_TBK1_ST	Q92985	IRF7	Q9UHD2	TBK1	S477	S479R	479	Missense	proximal	2	no	177.525	172.949	PhosphoSitePlus;EPSD	ICGC;COSMIC	145.681	Down-regulation
Other_IKK_TBK1_ST	Q92985	IRF7	Q9UHD2	TBK1	S477	S475N	475	Missense	proximal	-2	no	177.525	176.091	PhosphoSitePlus;EPSD	ICGC;COSMIC	145.681	Down-regulation
Other_IKK_TBK1_ST	Q92985	IRF7	Q9UHD2	TBK1	S479	C481R	481	Missense	proximal	2	no	186.700	188.193	EPSD;PhosphoSitePlus	ICGC;COSMIC	145.681	Up-regulation
Other_IKK_TBK1_ST	Q92985	IRF7	Q9UHD2	TBK1	S479	S479R	479	Missense	central	0	yes	186.700	0.000	EPSD;PhosphoSitePlus	ICGC;COSMIC	145.681	Loss
Other_IKK_TBK1_ST	Q92985	IRF7	Q9UHD2	TBK1	S479	S475N	475	Missense	distal	-4	no	186.700	185.561	EPSD;PhosphoSitePlus	ICGC;COSMIC	145.681	Down-regulation
Other_IKK_TBK1_ST	Q92985	IRF7	Q9UHD2	TBK1	S479	A485T	485	Missense	distal	6	no	186.700	181.160	EPSD;PhosphoSitePlus	ICGC;COSMIC	145.681	Down-regulation
Other_IKK_TBK1_ST	Q92985	IRF7	Q9UHD2	TBK1	S483	S487N	487	Missense	distal	4	no	166.191	159.992	EPSD	ICGC;COSMIC	145.681	Down-regulation
Other_IKK_TBK1_ST	Q92985	IRF7	Q9UHD2	TBK1	S483	C481R	481	Missense	proximal	-2	no	166.191	167.627	EPSD	ICGC;COSMIC	145.681	Up-regulation
Other_IKK_TBK1_ST	Q92985	IRF7	Q9UHD2	TBK1	S483	L488F	488	Missense	distal	5	no	166.191	164.309	EPSD	ICGC;COSMIC	145.681	Down-regulation
Other_IKK_TBK1_ST	Q92985	IRF7	Q9UHD2	TBK1	S483	S479R	479	Missense	distal	-4	no	166.191	164.821	EPSD	ICGC;COSMIC	145.681	Down-regulation
Other_IKK_TBK1_ST	Q92985	IRF7	Q9UHD2	TBK1	S483	A485T	485	Missense	proximal	2	no	166.191	167.860	EPSD	ICGC;COSMIC	145.681	Up-regulation
Other_IKK_TBK1_ST	Q92985	IRF7	Q9UHD2	TBK1	S487	I492T	492	Missense	distal	5	no	149.138	150.525	EPSD	ICGC;COSMIC	145.681	Up-regulation
Other_IKK_TBK1_ST	Q92985	IRF7	Q9UHD2	TBK1	S487	S487N	487	Missense	central	0	yes	149.138	0.000	EPSD	ICGC;COSMIC	145.681	Loss
Other_IKK_TBK1_ST	Q92985	IRF7	Q9UHD2	TBK1	S487	C481R	481	Missense	distal	-6	no	149.138	157.463	EPSD	ICGC;COSMIC	145.681	Up-regulation
Other_IKK_TBK1_ST	Q92985	IRF7	Q9UHD2	TBK1	S487	L488F	488	Missense	proximal	1	no	149.138	155.900	EPSD	ICGC;COSMIC	145.681	Up-regulation
Other_IKK_TBK1_ST	Q92985	IRF7	Q9UHD2	TBK1	S487	A485T	485	Missense	proximal	-2	no	149.138	149.527	EPSD	ICGC;COSMIC	145.681	Up-regulation
Other_IKK_TBK1_ST	Q9BRV8	SIKE1	Q9UHD2	TBK1	S185	L184I	184	Missense	proximal	-1	no	183.321	183.922	PhosphoSitePlus;EPSD	ICGC	145.681	Up-regulation
Other_IKK_TBK1_ST	Q9BRV8	SIKE1	Q9UHD2	TBK1	S187	L184I	184	Missense	distal	-3	no	187.867	184.429	EPSD;PhosphoSitePlus	ICGC	145.681	Down-regulation
Other_IKK_TBK1_ST	Q9BRV8	SIKE1	Q9UHD2	TBK1	S188	L184I	184	Missense	distal	-4	no	177.364	176.436	EPSD;PhosphoSitePlus	ICGC	145.681	Down-regulation
Other_IKK_TBK1_ST	Q9BRV8	SIKE1	Q9UHD2	TBK1	S190	L184I	184	Missense	distal	-6	no	200.159	198.857	EPSD;PhosphoSitePlus	ICGC	145.681	Down-regulation
Other_IKK_TBK1_ST	P31749	AKT1	Q9UHD2	TBK1	T87	H89R	89	Missense	proximal	2	no	145.011	146.602	EPSD	ICGC	145.681	Gain
Other_IKK_TBK1_ST	P31749	AKT1	Q9UHD2	TBK1	T308	T305N	305	Missense	distal	-3	no	166.338	161.712	EPSD;PhosphoSitePlus	ICGC	145.681	Down-regulation
Other_IKK_TBK1_ST	P31749	AKT1	Q9UHD2	TBK1	S457	V461L	461	Missense	distal	4	no	151.106	145.751	EPSD	ICGC;COSMIC	145.681	Down-regulation
Other_IKK_TBK1_ST	P31749	AKT1	Q9UHD2	TBK1	S457	M458L	458	Missense	proximal	1	no	151.106	156.532	EPSD	ICGC;COSMIC	145.681	Up-regulation
Other_IKK_TBK1_ST	P31749	AKT1	Q9UHD2	TBK1	S457	Q454K	454	Missense	distal	-3	no	151.106	144.024	EPSD	ICGC	145.681	Loss
Other_IKK_TBK1_ST	P31749	AKT1	Q9UHD2	TBK1	S457	S463R	463	Missense	distal	6	no	151.106	147.853	EPSD	ICGC;COSMIC	145.681	Down-regulation
Other_IKK_TBK1_ST	P31749	AKT1	Q9UHD2	TBK1	S457	S457R	457	Missense	central	0	yes	151.106	0.000	EPSD	ICGC	145.681	Loss
Other_IKK_TBK1_ST	P31749	AKT1	Q9UHD2	TBK1	S473	Q471K	471	Missense	proximal	-2	no	176.752	175.557	PhosphoSitePlus;EPSD	ICGC	145.681	Down-regulation
Other_IKK_TBK1_ST	P31749	AKT1	Q9UHD2	TBK1	S473	S477R	477	Missense	distal	4	no	176.752	172.629	PhosphoSitePlus;EPSD	ICGC	145.681	Down-regulation
Other_IKK_TBK1_ST	P31749	AKT1	Q9UHD2	TBK1	S475	Q471K	471	Missense	distal	-4	no	156.921	155.684	EPSD	ICGC	145.681	Down-regulation
Other_IKK_TBK1_ST	P31749	AKT1	Q9UHD2	TBK1	S475	S477R	477	Missense	proximal	2	no	156.921	152.345	EPSD	ICGC	145.681	Down-regulation
Other_IKK_TBK1_ST	P42226	STAT6	Q9UHD2	TBK1	S827	H828N	828	Missense	proximal	1	no	145.999	133.347	EPSD	ICGC	145.681	Loss
Other_IKK_TBK1_ST	P56962	STX17	Q9UHD2	TBK1	S134	L127I	127	Missense	distal	-7	no	161.066	160.357	EPSD	ICGC;COSMIC	145.681	Down-regulation
Other_IKK_TBK1_ST	P56962	STX17	Q9UHD2	TBK1	S202	S202N	202	Missense	central	0	yes	173.953	0.000	PhosphoSitePlus	ICGC;COSMIC	145.681	Loss
Other_IKK_TBK1_ST	P56962	STX17	Q9UHD2	TBK1	T287	S288F	288	Missense	proximal	1	no	142.268	164.434	EPSD	ICGC;COSMIC	145.681	Gain
Other_IKK_TBK1_ST	P56962	STX17	Q9UHD2	TBK1	T287	K281N	281	Missense	distal	-6	no	142.268	147.503	EPSD	ICGC	145.681	Gain
Other_IKK_TBK1_ST	P56962	STX17	Q9UHD2	TBK1	S295	S288F	288	Missense	distal	-7	no	160.970	159.034	EPSD	ICGC;COSMIC	145.681	Down-regulation
Other_IKK_TBK1_ST	P56962	STX17	Q9UHD2	TBK1	S295	C290F	290	Missense	distal	-5	no	160.970	161.521	EPSD	ICGC	145.681	Up-regulation
Other_IKK_TBK1_ST	P56962	STX17	Q9UHD2	TBK1	S295	C301F	301	Missense	distal	6	no	160.970	158.252	EPSD	ICGC	145.681	Down-regulation
Other_IKK_TBK1_ST	P56962	STX17	Q9UHD2	TBK1	S295	D292Y	292	Missense	distal	-3	no	160.970	159.941	EPSD	ICGC;COSMIC	145.681	Down-regulation
Other_IKK_TBK1_ST	Q9UHD2	TBK1	Q9UHD2	TBK1	T79	E76D	76	Missense	distal	-3	no	161.760	164.183	EPSD	ICGC;COSMIC	145.681	Up-regulation
Other_IKK_TBK1_ST	Q9UHD2	TBK1	Q9UHD2	TBK1	S172	D167Y	167	Missense	distal	-5	no	192.036	191.426	PhosphoSitePlus	ICGC	145.681	Down-regulation
Other_IKK_TBK1_ST	Q9UHD2	TBK1	Q9UHD2	TBK1	T176	H181Q	181	Missense	distal	5	no	158.077	160.550	EPSD	ICGC;COSMIC	145.681	Up-regulation
Other_IKK_TBK1_ST	Q9UHD2	TBK1	Q9UHD2	TBK1	S527	D523N	523	Missense	distal	-4	no	157.770	156.894	EPSD	ICGC;COSMIC	145.681	Down-regulation
Other_IKK_TBK1_ST	Q9UHD2	TBK1	Q9UHD2	TBK1	S527	R525S	525	Missense	proximal	-2	no	157.770	158.649	EPSD	ICGC;COSMIC	145.681	Up-regulation
Other_IKK_TBK1_ST	Q9UHD2	TBK1	Q9UHD2	TBK1	S716	G722V	722	Missense	distal	6	no	166.161	179.395	EPSD	ICGC;COSMIC	145.681	Up-regulation
Other_IKK_TBK1_ST	Q9UHD2	TBK1	Q9UHD2	TBK1	T718	G722V	722	Missense	distal	4	no	144.911	156.101	EPSD	ICGC;COSMIC	145.681	Gain
Other_IKK_TBK1_ST	Q13568	IRF5	Q9UHD2	TBK1	S293	R298H	298	Missense	distal	5	no	177.832	175.811	PhosphoSitePlus;EPSD	ICGC;COSMIC	145.681	Down-regulation
Other_IKK_TBK1_ST	Q13568	IRF5	Q9UHD2	TBK1	S293	G290V	290	Missense	distal	-3	no	177.832	175.712	PhosphoSitePlus;EPSD	ICGC	145.681	Down-regulation
Other_IKK_TBK1_ST	Q13568	IRF5	Q9UHD2	TBK1	S293	R298C	298	Missense	distal	5	no	177.832	174.108	PhosphoSitePlus;EPSD	ICGC;COSMIC	145.681	Down-regulation
Other_IKK_TBK1_ST	Q13568	IRF5	Q9UHD2	TBK1	S446	R453L	453	Missense	distal	7	no	159.504	159.442	EPSD	ICGC;COSMIC	145.681	Down-regulation
Other_IKK_TBK1_ST	Q13568	IRF5	Q9UHD2	TBK1	S446	R453C	453	Missense	distal	7	no	159.504	159.546	EPSD	ICGC;COSMIC	145.681	Up-regulation
Other_IKK_TBK1_ST	Q8IUC6	TICAM1	Q9UHD2	TBK1	S60	S60C	60	Missense	central	0	yes	158.797	0.000	EPSD	ICGC;COSMIC;GDSC	145.681	Loss
Other_IKK_TBK1_ST	Q8IUC6	TICAM1	Q9UHD2	TBK1	S223	R222S	222	Missense	proximal	-1	no	159.415	159.186	EPSD	ICGC;COSMIC	145.681	Down-regulation
Other_IKK_TBK1_ST	Q8IUC6	TICAM1	Q9UHD2	TBK1	S223	H221R	221	Missense	proximal	-2	no	159.415	159.652	EPSD	ICGC;COSMIC	145.681	Up-regulation
Other_IKK_TBK1_ST	Q8IUC6	TICAM1	Q9UHD2	TBK1	S343	P348L	348	Missense	distal	5	no	146.451	145.423	EPSD	ICGC;COSMIC	145.681	Loss
Other_IKK_TBK1_ST	Q04206	RELA	Q9UHD2	TBK1	S45	G48S	48	Missense	distal	3	no	150.604	149.009	EPSD	ICGC;COSMIC	145.681	Down-regulation
Other_IKK_TBK1_ST	Q04206	RELA	Q9UHD2	TBK1	S45	R41H	41	Missense	distal	-4	no	150.604	150.899	EPSD	ICGC;COSMIC	145.681	Up-regulation
Other_IKK_TBK1_ST	Q04206	RELA	Q9UHD2	TBK1	S319	P317H	317	Missense	proximal	-2	no	158.507	158.481	EPSD	ICGC;COSMIC	145.681	Down-regulation
Other_IKK_TBK1_ST	Q04206	RELA	Q9UHD2	TBK1	S319	G320R	320	Missense	proximal	1	no	158.507	168.046	EPSD	ICGC	145.681	Up-regulation
Other_IKK_TBK1_ST	Q04206	RELA	Q9UHD2	TBK1	S319	T322I	322	Missense	distal	3	no	158.507	157.873	EPSD	ICGC;COSMIC	145.681	Down-regulation
Other_IKK_TBK1_ST	Q04206	RELA	Q9UHD2	TBK1	S536	A538V	538	Missense	proximal	2	no	167.526	168.740	PhosphoSitePlus	ICGC;COSMIC	145.681	Up-regulation
Other_IKK_TBK1_ST	Q04206	RELA	Q9UHD2	TBK1	S543	A538V	538	Missense	distal	-5	no	162.263	162.894	EPSD	ICGC;COSMIC	145.681	Up-regulation
Other_IKK_TBK1_ST	Q04206	RELA	Q9UHD2	TBK1	S543	Q548P	548	Missense	distal	5	no	162.263	161.893	EPSD	ICGC;COSMIC	145.681	Down-regulation
Other_IKK_TBK1_ST	Q04206	RELA	Q9UHD2	TBK1	S547	Q548P	548	Missense	proximal	1	no	131.029	147.505	EPSD	ICGC;COSMIC	145.681	Gain
Other_IKK_TBK1_ST	Q7Z434	MAVS	Q9UHD2	TBK1	S94	R98Q	98	Missense	distal	4	no	165.735	165.837	EPSD	ICGC;COSMIC	145.681	Up-regulation
Other_IKK_TBK1_ST	Q7Z434	MAVS	Q9UHD2	TBK1	S94	Q93E	93	Missense	proximal	-1	no	165.735	166.190	EPSD	ICGC;COSMIC	145.681	Up-regulation
Other_IKK_TBK1_ST	Q7Z434	MAVS	Q9UHD2	TBK1	S100	R98Q	98	Missense	proximal	-2	no	149.638	150.233	EPSD	ICGC;COSMIC	145.681	Up-regulation
Other_IKK_TBK1_ST	Q7Z434	MAVS	Q9UHD2	TBK1	S100	Q93E	93	Missense	distal	-7	no	149.638	149.205	EPSD	ICGC;COSMIC	145.681	Down-regulation
Other_IKK_TBK1_ST	Q7Z434	MAVS	Q9UHD2	TBK1	S111	A114V	114	Missense	distal	3	no	190.929	191.393	EPSD	ICGC	145.681	Up-regulation
Other_IKK_TBK1_ST	Q7Z434	MAVS	Q9UHD2	TBK1	S180	S181F	181	Missense	proximal	1	no	131.624	153.790	EPSD	ICGC	145.681	Gain
Other_IKK_TBK1_ST	Q7Z434	MAVS	Q9UHD2	TBK1	S217	G219V	219	Missense	proximal	2	no	151.239	157.805	EPSD	ICGC	145.681	Up-regulation
Other_IKK_TBK1_ST	Q7Z434	MAVS	Q9UHD2	TBK1	S217	R218C	218	Missense	proximal	1	no	151.239	113.219	EPSD	ICGC;COSMIC	145.681	Loss
Other_IKK_TBK1_ST	Q7Z434	MAVS	Q9UHD2	TBK1	T250	S255Y	255	Missense	distal	5	no	154.502	151.315	EPSD	ICGC;COSMIC	145.681	Down-regulation
Other_IKK_TBK1_ST	Q7Z434	MAVS	Q9UHD2	TBK1	S253	P259S	259	Missense	distal	6	no	149.579	154.459	EPSD	ICGC;COSMIC	145.681	Up-regulation
Other_IKK_TBK1_ST	Q7Z434	MAVS	Q9UHD2	TBK1	S253	S255Y	255	Missense	proximal	2	no	149.579	140.941	EPSD	ICGC;COSMIC	145.681	Loss
Other_IKK_TBK1_ST	Q7Z434	MAVS	Q9UHD2	TBK1	S361	M358I	358	Missense	distal	-3	no	152.057	150.398	EPSD	ICGC;COSMIC	145.681	Down-regulation
Other_IKK_TBK1_ST	Q7Z434	MAVS	Q9UHD2	TBK1	S361	K362E	362	Missense	proximal	1	no	152.057	164.400	EPSD	ICGC	145.681	Up-regulation
Other_IKK_TBK1_ST	Q7Z434	MAVS	Q9UHD2	TBK1	S366	K362E	362	Missense	distal	-4	no	157.086	157.877	EPSD	ICGC	145.681	Up-regulation
Other_IKK_TBK1_ST	Q7Z434	MAVS	Q9UHD2	TBK1	T379	P378S	378	Missense	proximal	-1	no	150.045	149.642	EPSD	ICGC	145.681	Down-regulation
Other_IKK_TBK1_ST	Q7Z434	MAVS	Q9UHD2	TBK1	T379	D380G	380	Missense	proximal	1	no	150.045	147.813	EPSD	ICGC;COSMIC	145.681	Down-regulation
Other_IKK_TBK1_ST	Q7Z434	MAVS	Q9UHD2	TBK1	S383	P378S	378	Missense	distal	-5	no	149.201	150.167	EPSD	ICGC	145.681	Up-regulation
Other_IKK_TBK1_ST	Q7Z434	MAVS	Q9UHD2	TBK1	S383	D380G	380	Missense	distal	-3	no	149.201	151.394	EPSD	ICGC;COSMIC	145.681	Up-regulation
Other_IKK_TBK1_ST	Q7Z434	MAVS	Q9UHD2	TBK1	T388	P392Q	392	Missense	distal	4	no	147.669	149.871	EPSD	ICGC;COSMIC	145.681	Up-regulation
Other_IKK_TBK1_ST	Q7Z434	MAVS	Q9UHD2	TBK1	S401	S401I	401	Missense	central	0	yes	162.766	0.000	EPSD	ICGC;COSMIC	145.681	Loss
Other_IKK_TBK1_ST	Q7Z434	MAVS	Q9UHD2	TBK1	S408	G415W	415	Missense	distal	7	no	157.020	157.080	EPSD	ICGC	145.681	Up-regulation
Other_IKK_TBK1_ST	Q7Z434	MAVS	Q9UHD2	TBK1	S408	G415V	415	Missense	distal	7	no	157.020	157.019	EPSD	ICGC;COSMIC	145.681	Down-regulation
Other_IKK_TBK1_ST	Q7Z434	MAVS	Q9UHD2	TBK1	S408	S409F	409	Missense	proximal	1	no	157.020	179.186	EPSD	ICGC;COSMIC	145.681	Up-regulation
Other_IKK_TBK1_ST	Q7Z434	MAVS	Q9UHD2	TBK1	S408	S401I	401	Missense	distal	-7	no	157.020	156.390	EPSD	ICGC;COSMIC	145.681	Down-regulation
Other_IKK_TBK1_ST	P30086	PEBP1	Q9UHD2	TBK1	S52	S52R	52	Missense	central	0	yes	146.491	0.000	EPSD	ICGC;COSMIC	145.681	Loss
Other_IKK_TBK1_ST	P30086	PEBP1	Q9UHD2	TBK1	S52	D56G	56	Missense	distal	4	no	146.491	140.943	EPSD	ICGC	145.681	Loss
Other_IKK_TBK1_ST	P30086	PEBP1	Q9UHD2	TBK1	S52	N48D	48	Missense	distal	-4	no	146.491	147.367	EPSD	ICGC;COSMIC	145.681	Up-regulation
Other_IKK_TBK1_ST	P30086	PEBP1	Q9UHD2	TBK1	S60	D56G	56	Missense	distal	-4	no	153.647	152.744	EPSD	ICGC	145.681	Down-regulation
Other_IKK_TBK1_ST	P30086	PEBP1	Q9UHD2	TBK1	S98	M92V	92	Missense	distal	-6	no	145.978	150.609	EPSD	ICGC;COSMIC	145.681	Up-regulation
Other_IKK_TBK1_ST	P30086	PEBP1	Q9UHD2	TBK1	S98	N91Y	91	Missense	distal	-7	no	145.978	145.552	EPSD	ICGC;COSMIC	145.681	Loss
Other_IKK_TBK1_ST	P30086	PEBP1	Q9UHD2	TBK1	S99	M92V	92	Missense	distal	-7	no	158.633	158.435	EPSD	ICGC;COSMIC	145.681	Down-regulation
Other_IKK_TBK1_ST	P30086	PEBP1	Q9UHD2	TBK1	S109	G116S	116	Missense	distal	7	no	177.206	177.153	PhosphoSitePlus	ICGC;GDSC	145.681	Down-regulation
Other_IKK_TBK1_ST	P03372	ESR1	Q9UHD2	TBK1	S104	P99S	99	Missense	distal	-5	no	154.752	155.718	EPSD	ICGC	145.681	Up-regulation
Other_IKK_TBK1_ST	P03372	ESR1	Q9UHD2	TBK1	S104	S102N	102	Missense	proximal	-2	no	154.752	153.318	EPSD	ICGC;COSMIC	145.681	Down-regulation
Other_IKK_TBK1_ST	P03372	ESR1	Q9UHD2	TBK1	S104	N101S	101	Missense	distal	-3	no	154.752	163.471	EPSD	ICGC;COSMIC	145.681	Up-regulation
Other_IKK_TBK1_ST	P03372	ESR1	Q9UHD2	TBK1	S305	K302T	302	Missense	distal	-3	no	183.655	189.182	PhosphoSitePlus	ICGC;COSMIC	145.681	Up-regulation
Other_IKK_TBK1_ST	P03372	ESR1	Q9UHD2	TBK1	S305	R300L	300	Missense	distal	-5	no	183.655	184.493	PhosphoSitePlus	ICGC;COSMIC	145.681	Up-regulation
Other_IKK_TBK1_ST	P03372	ESR1	Q9UHD2	TBK1	S305	R300S	300	Missense	distal	-5	no	183.655	184.360	PhosphoSitePlus	ICGC;COSMIC	145.681	Up-regulation
Other_IKK_TBK1_ST	P03372	ESR1	Q9UHD2	TBK1	S305	R300H	300	Missense	distal	-5	no	183.655	182.843	PhosphoSitePlus	ICGC;COSMIC	145.681	Down-regulation
Other_IKK_TBK1_ST	P03372	ESR1	Q9UHD2	TBK1	S341	S341L	341	Missense	central	0	yes	174.879	0.000	EPSD	ICGC;COSMIC;GDSC;CCLE	145.681	Loss
Other_IKK_TBK1_ST	P03372	ESR1	Q9UHD2	TBK1	S341	P336A	336	Missense	distal	-5	no	174.879	175.378	EPSD	ICGC;COSMIC	145.681	Up-regulation
Other_IKK_TBK1_ST	P03372	ESR1	Q9UHD2	TBK1	S554	R555L	555	Missense	proximal	1	no	155.372	162.566	EPSD	ICGC	145.681	Up-regulation
Other_IKK_TBK1_ST	P03372	ESR1	Q9UHD2	TBK1	S573	S576L	576	Missense	distal	3	no	146.561	147.326	EPSD	ICGC;COSMIC	145.681	Up-regulation
Other_IKK_TBK1_ST	P03372	ESR1	Q9UHD2	TBK1	S575	S576L	576	Missense	proximal	1	no	135.363	150.767	EPSD	ICGC;COSMIC	145.681	Gain
Other_IKK_TBK1_ST	P03372	ESR1	Q9UHD2	TBK1	S578	S576L	576	Missense	proximal	-2	no	159.592	159.440	EPSD	ICGC;COSMIC	145.681	Down-regulation
CAMK_PKD_PRKD3_ST	Q9UQL6	HDAC5	O94806	PRKD3	S229	S225R	225	Missense	distal	-4	no	1.147	1.165	EPSD	ICGC;COSMIC	1.136	Up-regulation
CAMK_PKD_PRKD3_ST	Q15139	PRKD1	O94806	PRKD3	S218	R216H	216	Missense	proximal	-2	no	1.586	1.517	EPSD	ICGC	1.136	Down-regulation
CAMK_PKD_PRKD3_ST	Q15139	PRKD1	O94806	PRKD3	S239	E244V	244	Missense	distal	5	no	2.155	2.154	EPSD	ICGC;COSMIC	1.136	Down-regulation
CAMK_PKD_PRKD3_ST	Q15139	PRKD1	O94806	PRKD3	S412	R418K	418	Missense	distal	6	no	2.536	2.513	EPSD	ICGC;COSMIC	1.136	Down-regulation
CAMK_PKD_PRKD3_ST	Q15139	PRKD1	O94806	PRKD3	S738	R740W	740	Missense	proximal	2	no	5.753	5.761	PhosphoSitePlus;EPSD	ICGC;COSMIC;GDSC;CCLE	1.136	Up-regulation
CAMK_PKD_PRKD3_ST	Q15139	PRKD1	O94806	PRKD3	S738	R740L	740	Missense	proximal	2	no	5.753	5.761	PhosphoSitePlus;EPSD	ICGC;COSMIC	1.136	Up-regulation
CAMK_PKD_PRKD3_ST	Q15139	PRKD1	O94806	PRKD3	S742	R740W	740	Missense	proximal	-2	no	6.201	6.128	EPSD;PhosphoSitePlus	ICGC;COSMIC;GDSC;CCLE	1.136	Down-regulation
CAMK_PKD_PRKD3_ST	Q15139	PRKD1	O94806	PRKD3	S742	R740L	740	Missense	proximal	-2	no	6.201	6.027	EPSD;PhosphoSitePlus	ICGC;COSMIC	1.136	Down-regulation
CAMK_PKD_PRKD3_ST	Q9Y2X7	GIT1	O94806	PRKD3	S25	R26K	26	Missense	proximal	1	no	1.575	1.600	EPSD	ICGC	1.136	Up-regulation
CAMK_PKD_PRKD3_ST	Q9Y2X7	GIT1	O94806	PRKD3	S25	D32E	32	Missense	distal	7	no	1.575	1.571	EPSD	ICGC	1.136	Down-regulation
CAMK_PKD_PRKD3_ST	Q9Y2X7	GIT1	O94806	PRKD3	S46	R39W	39	Missense	distal	-7	no	5.616	5.522	PhosphoSitePlus	ICGC;COSMIC	1.136	Down-regulation
CAMK_PKD_PRKD3_ST	Q9Y2X7	GIT1	O94806	PRKD3	S46	R43C	43	Missense	distal	-3	no	5.616	5.559	PhosphoSitePlus	ICGC;COSMIC	1.136	Down-regulation
CAMK_PKD_PRKD3_ST	Q9Y2X7	GIT1	O94806	PRKD3	S46	R43H	43	Missense	distal	-3	no	5.616	5.590	PhosphoSitePlus	ICGC;CCLE	1.136	Down-regulation
CAMK_PKD_PRKD3_ST	Q9Y2X7	GIT1	O94806	PRKD3	S46	R52C	52	Missense	distal	6	no	5.616	5.584	PhosphoSitePlus	ICGC	1.136	Down-regulation
CAMK_PKD_PRKD3_ST	Q9Y2X7	GIT1	O94806	PRKD3	S46	R39L	39	Missense	distal	-7	no	5.616	5.110	PhosphoSitePlus	ICGC;COSMIC	1.136	Down-regulation
CAMK_PKD_PRKD3_ST	Q9Y2X7	GIT1	O94806	PRKD3	S54	T59M	59	Missense	distal	5	no	2.494	2.492	EPSD	ICGC	1.136	Down-regulation
CAMK_PKD_PRKD3_ST	Q9Y2X7	GIT1	O94806	PRKD3	S54	R52C	52	Missense	proximal	-2	no	2.494	2.397	EPSD	ICGC	1.136	Down-regulation
CAMK_PKD_PRKD3_ST	Q9Y2X7	GIT1	O94806	PRKD3	S254	E259K	259	Missense	distal	5	no	3.124	3.122	EPSD	ICGC;COSMIC	1.136	Down-regulation
CAMK_PKD_PRKD3_ST	Q9Y2X7	GIT1	O94806	PRKD3	S254	Q250H	250	Missense	distal	-4	no	3.124	3.107	EPSD	ICGC;COSMIC	1.136	Down-regulation
CAMK_PKD_PRKD3_ST	Q9Y2X7	GIT1	O94806	PRKD3	T307	R309C	309	Missense	proximal	2	no	1.729	1.743	EPSD	ICGC	1.136	Up-regulation
CAMK_PKD_PRKD3_ST	Q9Y2X7	GIT1	O94806	PRKD3	T307	R309H	309	Missense	proximal	2	no	1.729	1.741	EPSD	ICGC;COSMIC	1.136	Up-regulation
CAMK_PKD_PRKD3_ST	Q9Y2X7	GIT1	O94806	PRKD3	S449	R455W	455	Missense	distal	6	no	1.952	1.936	EPSD	ICGC;COSMIC	1.136	Down-regulation
CAMK_PKD_PRKD3_ST	Q9Y2X7	GIT1	O94806	PRKD3	S449	D452N	452	Missense	distal	3	no	1.952	1.970	EPSD	ICGC;COSMIC	1.136	Up-regulation
CAMK_PKD_PRKD3_ST	Q9Y2X7	GIT1	O94806	PRKD3	S449	E453K	453	Missense	distal	4	no	1.952	1.959	EPSD	ICGC;COSMIC	1.136	Up-regulation
CAMK_PKD_PRKD3_ST	Q9Y2X7	GIT1	O94806	PRKD3	S563	V565A	565	Missense	proximal	2	no	1.236	1.266	EPSD	ICGC;COSMIC	1.136	Up-regulation
CAMK_PKD_PRKD3_ST	Q9Y2X7	GIT1	O94806	PRKD3	S571	P572L	572	Missense	proximal	1	no	2.230	2.225	EPSD	ICGC;COSMIC	1.136	Down-regulation
CAMK_PKD_PRKD3_ST	Q9Y2X7	GIT1	O94806	PRKD3	S571	P572S	572	Missense	proximal	1	no	2.230	2.247	EPSD	ICGC;COSMIC	1.136	Up-regulation
CAMK_PKD_PRKD3_ST	Q9Y2X7	GIT1	O94806	PRKD3	S571	V565A	565	Missense	distal	-6	no	2.230	2.260	EPSD	ICGC;COSMIC	1.136	Up-regulation
CAMK_PKD_PRKD3_ST	Q9Y2X7	GIT1	O94806	PRKD3	S700	A707T	707	Missense	distal	7	no	1.372	1.334	EPSD	ICGC;COSMIC	1.136	Down-regulation
CAMK_PKD_PRKD3_ST	Q9Y2X7	GIT1	O94806	PRKD3	S700	R699W	699	Missense	proximal	-1	no	1.372	1.205	EPSD	ICGC;COSMIC	1.136	Down-regulation
AGC_PKC_PKCa_PRKCB_ST	P10636	MAPT	P05771-2	PRKCB	S171	R164T	164	Missense	distal	-7	no	2.924	3.136	EPSD	ICGC;COSMIC	0.942	Up-regulation
AGC_PKC_PKCa_PRKCB_ST	P10636	MAPT	P05771-2	PRKCB	S171	A166T	166	Missense	distal	-5	no	2.924	2.933	EPSD	ICGC	0.942	Up-regulation
AGC_PKC_PKCa_PRKCB_ST	P10636	MAPT	P05771-2	PRKCB	S214	G208C	208	Missense	distal	-6	no	1.656	1.653	EPSD	ICGC;COSMIC	0.942	Down-regulation
AGC_PKC_PKCa_PRKCB_ST	P10636	MAPT	P05771-2	PRKCB	S214	R211S	211	Missense	distal	-3	no	1.656	-1.741	EPSD	ICGC;COSMIC	0.942	Loss
AGC_PKC_PKCa_PRKCB_ST	P10636	MAPT	P05771-2	PRKCB	S214	G213E	213	Missense	proximal	-1	no	1.656	1.868	EPSD	ICGC;COSMIC	0.942	Up-regulation
AGC_PKC_PKCa_PRKCB_ST	P10636	MAPT	P05771-2	PRKCB	S355	A349T	349	Missense	distal	-6	no	3.476	3.617	EPSD	ICGC;COSMIC	0.942	Up-regulation
AGC_PKC_PKCa_PRKCB_ST	P10636	MAPT	P05771-2	PRKCB	S369	R364W	364	Missense	distal	-5	no	3.530	3.152	EPSD	ICGC;COSMIC	0.942	Down-regulation
AGC_PKC_PKCa_PRKCB_ST	P10636	MAPT	P05771-2	PRKCB	S369	P363L	363	Missense	distal	-6	no	3.530	3.546	EPSD	ICGC	0.942	Up-regulation
AGC_PKC_PKCa_PRKCB_ST	P10636	MAPT	P05771-2	PRKCB	S438	Y441H	441	Missense	distal	3	no	1.209	1.183	EPSD	ICGC;COSMIC	0.942	Down-regulation
AGC_PKC_PKCa_PRKCB_ST	P10636	MAPT	P05771-2	PRKCB	S519	G521R	521	Missense	proximal	2	no	-6.925	1.809	EPSD	ICGC;COSMIC	0.942	Gain
AGC_PKC_PKCa_PRKCB_ST	P10636	MAPT	P05771-2	PRKCB	S525	G521R	521	Missense	distal	-4	no	1.150	0.732	EPSD	ICGC;COSMIC	0.942	Loss
AGC_PKC_PKCa_PRKCB_ST	P05107	ITGB2	P05771-2	PRKCB	T118	R121L	121	Missense	distal	3	no	4.279	3.193	EPSD	ICGC;COSMIC	0.942	Down-regulation
AGC_PKC_PKCa_PRKCB_ST	P05107	ITGB2	P05771-2	PRKCB	S496	S496R	496	Missense	central	0	yes	3.467	0.000	EPSD	ICGC	0.942	Loss
AGC_PKC_PKCa_PRKCB_ST	P05107	ITGB2	P05771-2	PRKCB	S496	S489R	489	Missense	distal	-7	no	3.467	3.197	EPSD	ICGC	0.942	Down-regulation
AGC_PKC_PKCa_PRKCB_ST	Q8NER1	TRPV1	P05771-2	PRKCB	S186	K188R	188	Missense	proximal	2	no	0.213	1.837	EPSD	ICGC;COSMIC	0.942	Gain
AGC_PKC_PKCa_PRKCB_ST	Q8NER1	TRPV1	P05771-2	PRKCB	S194	A193V	193	Missense	proximal	-1	no	1.478	1.582	EPSD	ICGC;COSMIC	0.942	Up-regulation
AGC_PKC_PKCa_PRKCB_ST	Q8NER1	TRPV1	P05771-2	PRKCB	S194	E189D	189	Missense	distal	-5	no	1.478	1.451	EPSD	ICGC;COSMIC	0.942	Down-regulation
AGC_PKC_PKCa_PRKCB_ST	Q8NER1	TRPV1	P05771-2	PRKCB	S194	D197E	197	Missense	distal	3	no	1.478	1.732	EPSD	ICGC	0.942	Up-regulation
AGC_PKC_PKCa_PRKCB_ST	Q8NER1	TRPV1	P05771-2	PRKCB	S194	K188R	188	Missense	distal	-6	no	1.478	1.418	EPSD	ICGC;COSMIC	0.942	Down-regulation
AGC_PKC_PKCa_PRKCB_ST	Q8NER1	TRPV1	P05771-2	PRKCB	S194	K188N	188	Missense	distal	-6	no	1.478	1.301	EPSD	ICGC;COSMIC	0.942	Down-regulation
AGC_PKC_PKCa_PRKCB_ST	Q8NER1	TRPV1	P05771-2	PRKCB	S502	M503L	503	Missense	proximal	1	no	4.026	5.101	EPSD	ICGC	0.942	Up-regulation
AGC_PKC_PKCa_PRKCB_ST	Q8NER1	TRPV1	P05771-2	PRKCB	S502	L497M	497	Missense	distal	-5	no	4.026	4.034	EPSD	ICGC;COSMIC	0.942	Up-regulation
AGC_PKC_PKCa_PRKCB_ST	Q8NER1	TRPV1	P05771-2	PRKCB	T705	T705A	705	Missense	central	0	yes	2.523	0.000	PhosphoSitePlus	ICGC	0.942	Loss
AGC_PKC_PKCa_PRKCB_ST	Q8NER1	TRPV1	P05771-2	PRKCB	T705	T709M	709	Missense	distal	4	no	2.523	2.583	PhosphoSitePlus	ICGC;COSMIC;GDSC;CCLE	0.942	Up-regulation
AGC_PKC_PKCa_PRKCB_ST	Q8NER1	TRPV1	P05771-2	PRKCB	S712	T705A	705	Missense	distal	-7	no	2.279	2.307	EPSD	ICGC	0.942	Up-regulation
AGC_PKC_PKCa_PRKCB_ST	Q8NER1	TRPV1	P05771-2	PRKCB	S712	T709M	709	Missense	distal	-3	no	2.279	1.758	EPSD	ICGC;COSMIC;GDSC;CCLE	0.942	Down-regulation
AGC_PKC_PKCa_PRKCB_ST	Q8NER1	TRPV1	P05771-2	PRKCB	T773	S775R	775	Missense	proximal	2	no	-0.249	5.748	EPSD	ICGC;COSMIC	0.942	Gain
AGC_PKC_PKCa_PRKCB_ST	Q8NER1	TRPV1	P05771-2	PRKCB	S777	V770I	770	Missense	distal	-7	no	3.143	2.974	EPSD	ICGC;COSMIC	0.942	Down-regulation
AGC_PKC_PKCa_PRKCB_ST	Q8NER1	TRPV1	P05771-2	PRKCB	S777	R779W	779	Missense	proximal	2	no	3.143	-6.371	EPSD	ICGC;COSMIC;GDSC	0.942	Loss
AGC_PKC_PKCa_PRKCB_ST	Q8NER1	TRPV1	P05771-2	PRKCB	S777	R772C	772	Missense	distal	-5	no	3.143	2.909	EPSD	ICGC	0.942	Down-regulation
AGC_PKC_PKCa_PRKCB_ST	Q8NER1	TRPV1	P05771-2	PRKCB	S777	R782S	782	Missense	distal	5	no	3.143	2.736	EPSD	ICGC;COSMIC	0.942	Down-regulation
AGC_PKC_PKCa_PRKCB_ST	Q8NER1	TRPV1	P05771-2	PRKCB	S777	S775R	775	Missense	proximal	-2	no	3.143	5.096	EPSD	ICGC;COSMIC	0.942	Up-regulation
AGC_PKC_PKCa_PRKCB_ST	Q8NER1	TRPV1	P05771-2	PRKCB	S777	S781I	781	Missense	distal	4	no	3.143	3.284	EPSD	ICGC;COSMIC	0.942	Up-regulation
AGC_PKC_PKCa_PRKCB_ST	Q8NER1	TRPV1	P05771-2	PRKCB	S777	S777P	777	Missense	central	0	yes	3.143	0.000	EPSD	ICGC;COSMIC	0.942	Loss
AGC_PKC_PKCa_PRKCB_ST	Q8NER1	TRPV1	P05771-2	PRKCB	S777	F776L	776	Missense	proximal	-1	no	3.143	2.985	EPSD	ICGC;COSMIC	0.942	Down-regulation
AGC_PKC_PKCa_PRKCB_ST	Q8NER1	TRPV1	P05771-2	PRKCB	S777	R772H	772	Missense	distal	-5	no	3.143	2.895	EPSD	ICGC;COSMIC;CCLE	0.942	Down-regulation
AGC_PKC_PKCa_PRKCB_ST	Q8NER1	TRPV1	P05771-2	PRKCB	S780	S781I	781	Missense	proximal	1	no	0.142	1.416	EPSD	ICGC;COSMIC	0.942	Gain
AGC_PKC_PKCa_PRKCB_ST	Q8NER1	TRPV1	P05771-2	PRKCB	S784	R779W	779	Missense	distal	-5	no	1.337	0.959	EPSD	ICGC;COSMIC;GDSC	0.942	Down-regulation
AGC_PKC_PKCa_PRKCB_ST	Q8NER1	TRPV1	P05771-2	PRKCB	S784	K789N	789	Missense	distal	5	no	1.337	0.964	EPSD	ICGC;COSMIC	0.942	Down-regulation
AGC_PKC_PKCa_PRKCB_ST	Q8NER1	TRPV1	P05771-2	PRKCB	S784	H787Q	787	Missense	distal	3	no	1.337	1.578	EPSD	ICGC	0.942	Up-regulation
AGC_PKC_PKCa_PRKCB_ST	Q8NER1	TRPV1	P05771-2	PRKCB	S784	W788L	788	Missense	distal	4	no	1.337	1.774	EPSD	ICGC;COSMIC	0.942	Up-regulation
AGC_PKC_PKCa_PRKCB_ST	Q8NER1	TRPV1	P05771-2	PRKCB	S784	R782S	782	Missense	proximal	-2	no	1.337	-0.616	EPSD	ICGC;COSMIC	0.942	Loss
AGC_PKC_PKCa_PRKCB_ST	Q8NER1	TRPV1	P05771-2	PRKCB	S784	S781I	781	Missense	distal	-3	no	1.337	1.538	EPSD	ICGC;COSMIC	0.942	Up-regulation
AGC_PKC_PKCa_PRKCB_ST	Q8NER1	TRPV1	P05771-2	PRKCB	S784	S777P	777	Missense	distal	-7	no	1.337	1.462	EPSD	ICGC;COSMIC	0.942	Up-regulation
AGC_PKC_PKCa_PRKCB_ST	Q8NER1	TRPV1	P05771-2	PRKCB	S801	Q806K	806	Missense	distal	5	no	7.183	7.221	EPSD	ICGC	0.942	Up-regulation
AGC_PKC_PKCa_PRKCB_ST	Q8NER1	TRPV1	P05771-2	PRKCB	S801	A808D	808	Missense	distal	7	no	7.183	6.969	EPSD	ICGC;COSMIC	0.942	Down-regulation
AGC_PKC_PKCa_PRKCB_ST	Q8NER1	TRPV1	P05771-2	PRKCB	S801	A808V	808	Missense	distal	7	no	7.183	7.128	EPSD	ICGC;COSMIC	0.942	Down-regulation
AGC_PKC_PKCa_PRKCB_ST	Q8NER1	TRPV1	P05771-2	PRKCB	S807	Q809R	809	Missense	proximal	2	no	-5.422	1.127	EPSD	ICGC;COSMIC	0.942	Gain
AGC_PKC_PKCa_PRKCB_ST	Q8NER1	TRPV1	P05771-2	PRKCB	S821	A827D	827	Missense	distal	6	no	0.361	0.943	EPSD	ICGC;COSMIC	0.942	Gain
AGC_PKC_PKCa_PRKCB_ST	P98082	DAB2	P05771-2	PRKCB	S24	A19S	19	Missense	distal	-5	no	12.413	12.371	PhosphoSitePlus	ICGC	0.942	Down-regulation
AGC_PKC_PKCa_PRKCB_ST	P98082	DAB2	P05771-2	PRKCB	S208	L206M	206	Missense	proximal	-2	no	0.488	0.969	EPSD	ICGC	0.942	Gain
AGC_PKC_PKCa_PRKCB_ST	P98082	DAB2	P05771-2	PRKCB	S249	S249C	249	Missense	central	0	yes	4.764	0.000	EPSD	ICGC;COSMIC	0.942	Loss
AGC_PKC_PKCa_PRKCB_ST	P98082	DAB2	P05771-2	PRKCB	S249	T245A	245	Missense	distal	-4	no	4.764	4.868	EPSD	ICGC;COSMIC	0.942	Up-regulation
AGC_PKC_PKCa_PRKCB_ST	P98082	DAB2	P05771-2	PRKCB	S249	Q247K	247	Missense	proximal	-2	no	4.764	5.845	EPSD	ICGC	0.942	Up-regulation
AGC_PKC_PKCa_PRKCB_ST	P98082	DAB2	P05771-2	PRKCB	S249	P254L	254	Missense	distal	5	no	4.764	4.771	EPSD	ICGC	0.942	Up-regulation
AGC_PKC_PKCa_PRKCB_ST	P98082	DAB2	P05771-2	PRKCB	S262	G259R	259	Missense	distal	-3	no	-3.250	0.966	EPSD	ICGC;COSMIC	0.942	Gain
AGC_PKC_PKCa_PRKCB_ST	P98082	DAB2	P05771-2	PRKCB	S313	S310L	310	Missense	distal	-3	no	1.710	0.949	EPSD	ICGC;COSMIC;GDSC;CCLE	0.942	Down-regulation
AGC_PKC_PKCa_PRKCB_ST	P98082	DAB2	P05771-2	PRKCB	S390	P395L	395	Missense	distal	5	no	3.515	3.522	EPSD	ICGC;COSMIC	0.942	Up-regulation
AGC_PKC_PKCa_PRKCB_ST	P98082	DAB2	P05771-2	PRKCB	S390	S393Y	393	Missense	distal	3	no	3.515	3.501	EPSD	ICGC;COSMIC	0.942	Down-regulation
AGC_PKC_PKCa_PRKCB_ST	P98082	DAB2	P05771-2	PRKCB	S390	E385K	385	Missense	distal	-5	no	3.515	3.588	EPSD	ICGC;COSMIC	0.942	Up-regulation
AGC_PKC_PKCa_PRKCB_ST	P98082	DAB2	P05771-2	PRKCB	S390	P397L	397	Missense	distal	7	no	3.515	3.482	EPSD	ICGC	0.942	Down-regulation
AGC_PKC_PKCa_PRKCB_ST	P98082	DAB2	P05771-2	PRKCB	S407	S407Y	407	Missense	central	0	yes	1.602	0.000	EPSD	ICGC;COSMIC	0.942	Loss
AGC_PKC_PKCa_PRKCB_ST	P98082	DAB2	P05771-2	PRKCB	S407	S401R	401	Missense	distal	-6	no	1.602	1.815	EPSD	ICGC;COSMIC	0.942	Up-regulation
AGC_PKC_PKCa_PRKCB_ST	P98082	DAB2	P05771-2	PRKCB	S407	P403S	403	Missense	distal	-4	no	1.602	1.505	EPSD	ICGC;COSMIC	0.942	Down-regulation
AGC_PKC_PKCa_PRKCB_ST	P98082	DAB2	P05771-2	PRKCB	S407	Q414E	414	Missense	distal	7	no	1.602	1.658	EPSD	ICGC;COSMIC	0.942	Up-regulation
AGC_PKC_PKCa_PRKCB_ST	P98082	DAB2	P05771-2	PRKCB	S436	P433H	433	Missense	distal	-3	no	1.854	2.080	EPSD	ICGC;COSMIC	0.942	Up-regulation
AGC_PKC_PKCa_PRKCB_ST	P05771	PRKCB	P05771-2	PRKCB	S16	E12D	12	Missense	distal	-4	no	2.322	2.428	EPSD	ICGC;COSMIC	0.942	Up-regulation
AGC_PKC_PKCa_PRKCB_ST	P05771	PRKCB	P05771-2	PRKCB	S16	P10T	10	Missense	distal	-6	no	2.322	2.499	EPSD	ICGC;COSMIC	0.942	Up-regulation
AGC_PKC_PKCa_PRKCB_ST	P05771	PRKCB	P05771-2	PRKCB	T17	E12D	12	Missense	distal	-5	no	3.564	3.537	EPSD	ICGC;COSMIC	0.942	Down-regulation
AGC_PKC_PKCa_PRKCB_ST	P05771	PRKCB	P05771-2	PRKCB	T17	G24V	24	Missense	distal	7	no	3.564	3.495	EPSD	ICGC;COSMIC;CCLE	0.942	Down-regulation
AGC_PKC_PKCa_PRKCB_ST	P05771	PRKCB	P05771-2	PRKCB	T17	P10T	10	Missense	distal	-7	no	3.564	3.380	EPSD	ICGC;COSMIC	0.942	Down-regulation
AGC_PKC_PKCa_PRKCB_ST	P05771	PRKCB	P05771-2	PRKCB	T40	T40I	40	Missense	central	0	yes	3.397	0.000	EPSD	ICGC;COSMIC;GDSC;CCLE	0.942	Loss
AGC_PKC_PKCa_PRKCB_ST	P05771	PRKCB	P05771-2	PRKCB	T40	F44I	44	Missense	distal	4	no	3.397	3.688	EPSD	ICGC;COSMIC	0.942	Up-regulation
AGC_PKC_PKCa_PRKCB_ST	P05771	PRKCB	P05771-2	PRKCB	T48	F44I	44	Missense	distal	-4	no	2.065	2.058	EPSD	ICGC;COSMIC	0.942	Down-regulation
AGC_PKC_PKCa_PRKCB_ST	P05771	PRKCB	P05771-2	PRKCB	S111	C118F	118	Missense	distal	7	no	2.681	2.711	EPSD	ICGC	0.942	Up-regulation
AGC_PKC_PKCa_PRKCB_ST	P05771	PRKCB	P05771-2	PRKCB	S111	D116G	116	Missense	distal	5	no	2.681	2.440	EPSD	ICGC	0.942	Down-regulation
AGC_PKC_PKCa_PRKCB_ST	P05771	PRKCB	P05771-2	PRKCB	S208	S206R	206	Missense	proximal	-2	no	0.458	2.411	EPSD	ICGC	0.942	Gain
AGC_PKC_PKCa_PRKCB_ST	P05771	PRKCB	P05771-2	PRKCB	T314	K315T	315	Missense	proximal	1	no	1.587	-0.386	EPSD	ICGC	0.942	Loss
AGC_PKC_PKCa_PRKCB_ST	P05771	PRKCB	P05771-2	PRKCB	T314	A308S	308	Missense	distal	-6	no	1.587	1.664	EPSD	ICGC	0.942	Up-regulation
AGC_PKC_PKCa_PRKCB_ST	P05771	PRKCB	P05771-2	PRKCB	T314	R307M	307	Missense	distal	-7	no	1.587	1.964	EPSD	ICGC;COSMIC	0.942	Up-regulation
AGC_PKC_PKCa_PRKCB_ST	P05771	PRKCB	P05771-2	PRKCB	T500	G495V	495	Missense	distal	-5	no	2.613	2.633	EPSD	ICGC;COSMIC	0.942	Up-regulation
AGC_PKC_PKCa_PRKCB_ST	P05771	PRKCB	P05771-2	PRKCB	T500	K499N	499	Missense	proximal	-1	no	2.613	2.330	EPSD	ICGC;COSMIC	0.942	Down-regulation
AGC_PKC_PKCa_PRKCB_ST	P53004	BLVRA	P05771-2	PRKCB	S21	R28W	28	Missense	distal	7	no	6.698	6.999	EPSD	ICGC;COSMIC;GDSC;CCLE	0.942	Up-regulation
AGC_PKC_PKCa_PRKCB_ST	P53004	BLVRA	P05771-2	PRKCB	S21	G15D	15	Missense	distal	-6	no	6.698	6.868	EPSD	ICGC;COSMIC	0.942	Up-regulation
AGC_PKC_PKCa_PRKCB_ST	P53004	BLVRA	P05771-2	PRKCB	S21	G15V	15	Missense	distal	-6	no	6.698	6.826	EPSD	ICGC	0.942	Up-regulation
AGC_PKC_PKCa_PRKCB_ST	P53004	BLVRA	P05771-2	PRKCB	S230	S235T	235	Missense	distal	5	no	1.308	1.375	PhosphoSitePlus;EPSD	ICGC;COSMIC	0.942	Up-regulation
AGC_PKC_PKCa_PRKCB_ST	Q07869	PPARA	P05771-2	PRKCB	S179	E180D	180	Missense	proximal	1	no	2.928	3.104	EPSD;PhosphoSitePlus	ICGC	0.942	Up-regulation
AGC_PKC_PKCa_PRKCB_ST	Q07869	PPARA	P05771-2	PRKCB	S230	V227A	227	Missense	distal	-3	no	2.949	1.236	PhosphoSitePlus;EPSD	ICGC;COSMIC	0.942	Down-regulation
AGC_PKC_PKCa_PRKCB_ST	Q07869	PPARA	P05771-2	PRKCB	S230	P237Q	237	Missense	distal	7	no	2.949	2.761	PhosphoSitePlus;EPSD	ICGC;COSMIC	0.942	Down-regulation
AGC_PKC_PKCa_PRKCB_ST	P15336	ATF2	P05771-2	PRKCB	S314	S321G	321	Missense	distal	7	no	1.491	1.621	EPSD	ICGC;COSMIC	0.942	Up-regulation
AGC_PKC_PKCa_PRKCB_ST	P15336	ATF2	P05771-2	PRKCB	S340	S340L	340	Missense	central	0	yes	2.871	0.000	EPSD	ICGC;COSMIC	0.942	Loss
AGC_PKC_PKCa_PRKCB_ST	P15336	ATF2	P05771-2	PRKCB	S340	Q337H	337	Missense	distal	-3	no	2.871	3.083	EPSD	ICGC;COSMIC	0.942	Up-regulation
AGC_PKC_PKCa_PRKCB_ST	P15336	ATF2	P05771-2	PRKCB	S367	A365V	365	Missense	proximal	-2	no	0.774	0.986	EPSD	ICGC;COSMIC	0.942	Gain
AGC_PKC_PKCa_PRKCB_ST	P43629	KIR3DL1	P05771-2	PRKCB	S296	R298C	298	Missense	proximal	2	no	2.010	-2.483	EPSD	ICGC;COSMIC;GDSC	0.942	Loss
AGC_PKC_PKCa_PRKCB_ST	P43629	KIR3DL1	P05771-2	PRKCB	S415	T412M	412	Missense	distal	-3	no	7.824	7.303	PhosphoSitePlus	ICGC;COSMIC	0.942	Down-regulation
AGC_PKC_PKCa_PRKCB_ST	P43629	KIR3DL1	P05771-2	PRKCB	S415	P418T	418	Missense	distal	3	no	7.824	7.937	PhosphoSitePlus	ICGC	0.942	Up-regulation
AGC_PKC_PKCa_PRKCB_ST	P43629	KIR3DL1	P05771-2	PRKCB	S415	P414T	414	Missense	proximal	-1	no	7.824	8.066	PhosphoSitePlus	ICGC	0.942	Up-regulation
AGC_PKC_PKCa_PRKCB_ST	P43629	KIR3DL1	P05771-2	PRKCB	S415	Q416L	416	Missense	proximal	1	no	7.824	7.838	PhosphoSitePlus	ICGC	0.942	Up-regulation
AGC_PKC_PKCa_PRKCB_ST	P43629	KIR3DL1	P05771-2	PRKCB	S415	R413L	413	Missense	proximal	-2	no	7.824	5.304	PhosphoSitePlus	ICGC;COSMIC	0.942	Down-regulation
AGC_PKC_PKCa_PRKCB_ST	P43629	KIR3DL1	P05771-2	PRKCB	S415	P418L	418	Missense	distal	3	no	7.824	7.437	PhosphoSitePlus	ICGC	0.942	Down-regulation
AGC_PKC_PKCa_PRKCB_ST	P56537	EIF6	P05771-2	PRKCB	S6	N9K	9	Missense	distal	3	no	1.585	1.731	EPSD	ICGC	0.942	Up-regulation
AGC_PKC_PKCa_PRKCB_ST	Q06124	PTPN11	P05771-2	PRKCB	S28	A31S	31	Missense	distal	3	no	0.909	1.122	EPSD	ICGC	0.942	Gain
AGC_PKC_PKCa_PRKCB_ST	Q06124	PTPN11	P05771-2	PRKCB	S34	A31S	31	Missense	distal	-3	no	0.684	1.215	EPSD	ICGC	0.942	Gain
AGC_PKC_PKCa_PRKCB_ST	Q06124	PTPN11	P05771-2	PRKCB	S140	P144H	144	Missense	distal	4	no	1.121	1.182	EPSD	ICGC;COSMIC	0.942	Up-regulation
AGC_PKC_PKCa_PRKCB_ST	Q06124	PTPN11	P05771-2	PRKCB	S140	E139D	139	Missense	proximal	-1	no	1.121	1.035	EPSD	ICGC;COSMIC	0.942	Down-regulation
AGC_PKC_PKCa_PRKCB_ST	Q06124	PTPN11	P05771-2	PRKCB	S160	G158W	158	Missense	proximal	-2	no	0.985	-0.424	EPSD	ICGC	0.942	Loss
AGC_PKC_PKCa_PRKCB_ST	Q06124	PTPN11	P05771-2	PRKCB	S160	D155Y	155	Missense	distal	-5	no	0.985	0.982	EPSD	ICGC;COSMIC	0.942	Down-regulation
AGC_PKC_PKCa_PRKCB_ST	P49841	GSK3B	P05771-2	PRKCB	S9	A11S	11	Missense	proximal	2	no	2.332	4.335	PhosphoSitePlus	ICGC;COSMIC	0.942	Up-regulation
AGC_PKC_PKCa_PRKCB_ST	P49841	GSK3B	P05771-2	PRKCB	S13	A11S	11	Missense	proximal	-2	no	1.665	1.504	EPSD	ICGC;COSMIC	0.942	Down-regulation
AGC_PKC_PKCa_PRKCB_ST	P49841	GSK3B	P05771-2	PRKCB	S35	D33E	33	Missense	proximal	-2	no	2.853	3.766	EPSD	ICGC	0.942	Up-regulation
AGC_PKC_PKCa_PRKCB_ST	P49841	GSK3B	P05771-2	PRKCB	S55	Q52K	52	Missense	distal	-3	no	-1.443	1.986	EPSD	ICGC	0.942	Gain
AGC_PKC_PKCa_PRKCB_ST	P49841	GSK3B	P05771-2	PRKCB	S147	A149D	149	Missense	proximal	2	no	0.378	1.733	EPSD	ICGC	0.942	Gain
AGC_PKC_PKCa_PRKCB_ST	P49841	GSK3B	P05771-2	PRKCB	S147	Q151R	151	Missense	distal	4	no	0.378	0.998	EPSD	ICGC;COSMIC	0.942	Gain
AGC_PKC_PKCa_PRKCB_ST	P49841	GSK3B	P05771-2	PRKCB	T275	L273R	273	Missense	proximal	-2	no	-1.561	0.959	EPSD	ICGC	0.942	Gain
AGC_PKC_PKCa_PRKCB_ST	P35579	MYH9	P05771-2	PRKCB	S197	Y193H	193	Missense	distal	-4	no	3.845	3.955	EPSD	ICGC;COSMIC	0.942	Up-regulation
AGC_PKC_PKCa_PRKCB_ST	P35579	MYH9	P05771-2	PRKCB	S197	H198N	198	Missense	proximal	1	no	3.845	2.845	EPSD	ICGC	0.942	Down-regulation
AGC_PKC_PKCa_PRKCB_ST	P35579	MYH9	P05771-2	PRKCB	T226	N223K	223	Missense	distal	-3	no	0.035	3.196	EPSD	ICGC	0.942	Gain
AGC_PKC_PKCa_PRKCB_ST	P35579	MYH9	P05771-2	PRKCB	S344	V342D	342	Missense	proximal	-2	no	3.033	2.367	EPSD	ICGC;COSMIC	0.942	Down-regulation
AGC_PKC_PKCa_PRKCB_ST	P35579	MYH9	P05771-2	PRKCB	S344	N351S	351	Missense	distal	7	no	3.033	3.050	EPSD	ICGC;COSMIC	0.942	Up-regulation
AGC_PKC_PKCa_PRKCB_ST	P35579	MYH9	P05771-2	PRKCB	S344	R341L	341	Missense	distal	-3	no	3.033	-1.124	EPSD	ICGC;COSMIC	0.942	Loss
AGC_PKC_PKCa_PRKCB_ST	P35579	MYH9	P05771-2	PRKCB	S541	P535H	535	Missense	distal	-6	no	1.313	1.395	EPSD	ICGC;COSMIC	0.942	Up-regulation
AGC_PKC_PKCa_PRKCB_ST	P35579	MYH9	P05771-2	PRKCB	S541	Q548H	548	Missense	distal	7	no	1.313	1.463	EPSD	ICGC;COSMIC	0.942	Up-regulation
AGC_PKC_PKCa_PRKCB_ST	P35579	MYH9	P05771-2	PRKCB	T725	P726Q	726	Missense	proximal	1	no	1.022	2.144	EPSD	ICGC;COSMIC	0.942	Up-regulation
AGC_PKC_PKCa_PRKCB_ST	P35579	MYH9	P05771-2	PRKCB	T725	P730H	730	Missense	distal	5	no	1.022	1.108	EPSD	ICGC;COSMIC	0.942	Up-regulation
AGC_PKC_PKCa_PRKCB_ST	P35579	MYH9	P05771-2	PRKCB	S957	Q960K	960	Missense	distal	3	no	4.481	4.589	EPSD	ICGC	0.942	Up-regulation
AGC_PKC_PKCa_PRKCB_ST	P35579	MYH9	P05771-2	PRKCB	S1122	R1124C	1124	Missense	proximal	2	no	1.709	-2.784	EPSD	ICGC	0.942	Loss
AGC_PKC_PKCa_PRKCB_ST	P35579	MYH9	P05771-2	PRKCB	S1122	R1124S	1124	Missense	proximal	2	no	1.709	-4.288	EPSD	ICGC	0.942	Loss
AGC_PKC_PKCa_PRKCB_ST	P35579	MYH9	P05771-2	PRKCB	S1122	R1127G	1127	Missense	distal	5	no	1.709	1.280	EPSD	ICGC;COSMIC	0.942	Down-regulation
AGC_PKC_PKCa_PRKCB_ST	P35579	MYH9	P05771-2	PRKCB	S1122	N1128Y	1128	Missense	distal	6	no	1.709	1.113	EPSD	ICGC;COSMIC	0.942	Down-regulation
AGC_PKC_PKCa_PRKCB_ST	P35579	MYH9	P05771-2	PRKCB	T1208	R1210Q	1210	Missense	proximal	2	no	2.263	-4.286	EPSD	ICGC;COSMIC	0.942	Loss
AGC_PKC_PKCa_PRKCB_ST	P35579	MYH9	P05771-2	PRKCB	S1243	Q1238K	1238	Missense	distal	-5	no	2.520	2.499	EPSD	ICGC	0.942	Down-regulation
AGC_PKC_PKCa_PRKCB_ST	P35579	MYH9	P05771-2	PRKCB	S1243	V1250L	1250	Missense	distal	7	no	2.520	2.518	EPSD	ICGC;COSMIC	0.942	Down-regulation
AGC_PKC_PKCa_PRKCB_ST	P35579	MYH9	P05771-2	PRKCB	S1294	Q1291R	1291	Missense	distal	-3	no	-1.023	2.175	EPSD	ICGC;COSMIC	0.942	Gain
AGC_PKC_PKCa_PRKCB_ST	P35579	MYH9	P05771-2	PRKCB	S1328	L1331R	1331	Missense	distal	3	no	0.322	1.407	EPSD	ICGC;COSMIC	0.942	Gain
AGC_PKC_PKCa_PRKCB_ST	P35579	MYH9	P05771-2	PRKCB	S1328	S1326R	1326	Missense	proximal	-2	no	0.322	2.275	EPSD	ICGC;COSMIC	0.942	Gain
AGC_PKC_PKCa_PRKCB_ST	P35579	MYH9	P05771-2	PRKCB	T1329	L1331R	1331	Missense	proximal	2	no	-4.705	1.927	EPSD	ICGC;COSMIC	0.942	Gain
AGC_PKC_PKCa_PRKCB_ST	P35579	MYH9	P05771-2	PRKCB	S1340	S1340Y	1340	Missense	central	0	yes	6.141	0.000	EPSD	ICGC	0.942	Loss
AGC_PKC_PKCa_PRKCB_ST	P35579	MYH9	P05771-2	PRKCB	S1398	S1398R	1398	Missense	central	0	yes	4.442	0.000	EPSD	ICGC;COSMIC	0.942	Loss
AGC_PKC_PKCa_PRKCB_ST	P35579	MYH9	P05771-2	PRKCB	S1398	D1393H	1393	Missense	distal	-5	no	4.442	4.333	EPSD	ICGC;COSMIC	0.942	Down-regulation
AGC_PKC_PKCa_PRKCB_ST	P35579	MYH9	P05771-2	PRKCB	S1526	R1528L	1528	Missense	proximal	2	no	1.959	-4.673	EPSD	ICGC;COSMIC	0.942	Loss
AGC_PKC_PKCa_PRKCB_ST	P35579	MYH9	P05771-2	PRKCB	S1808	A1811T	1811	Missense	distal	3	no	1.603	1.996	EPSD	ICGC;COSMIC	0.942	Up-regulation
AGC_PKC_PKCa_PRKCB_ST	P35579	MYH9	P05771-2	PRKCB	S1808	A1807S	1807	Missense	proximal	-1	no	1.603	1.574	EPSD	ICGC;COSMIC	0.942	Down-regulation
AGC_PKC_PKCa_PRKCB_ST	P35579	MYH9	P05771-2	PRKCB	S1869	D1866N	1866	Missense	distal	-3	no	0.650	1.619	EPSD	ICGC;COSMIC	0.942	Gain
AGC_PKC_PKCa_PRKCB_ST	P35579	MYH9	P05771-2	PRKCB	S1892	R1888Q	1888	Missense	distal	-4	no	3.035	3.156	EPSD	ICGC	0.942	Up-regulation
AGC_PKC_PKCa_PRKCB_ST	P35579	MYH9	P05771-2	PRKCB	S1892	R1893S	1893	Missense	proximal	1	no	3.035	1.011	EPSD	ICGC;COSMIC	0.942	Down-regulation
AGC_PKC_PKCa_PRKCB_ST	P35579	MYH9	P05771-2	PRKCB	S1892	R1893L	1893	Missense	proximal	1	no	3.035	2.351	EPSD	ICGC;COSMIC	0.942	Down-regulation
AGC_PKC_PKCa_PRKCB_ST	P35579	MYH9	P05771-2	PRKCB	S1892	R1893G	1893	Missense	proximal	1	no	3.035	0.926	EPSD	ICGC;COSMIC	0.942	Loss
AGC_PKC_PKCa_PRKCB_ST	P35579	MYH9	P05771-2	PRKCB	S1916	R1912C	1912	Missense	distal	-4	no	4.740	5.245	PhosphoSitePlus	ICGC;COSMIC	0.942	Up-regulation
AGC_PKC_PKCa_PRKCB_ST	Q9UBS0	RPS6KB2	P05771-2	PRKCB	T228	V225I	225	Missense	distal	-3	no	1.590	0.611	EPSD	ICGC;COSMIC	0.942	Loss
AGC_PKC_PKCa_PRKCB_ST	Q9UBS0	RPS6KB2	P05771-2	PRKCB	T228	I233T	233	Missense	distal	5	no	1.590	1.570	EPSD	ICGC;COSMIC	0.942	Down-regulation
AGC_PKC_PKCa_PRKCB_ST	Q9UBS0	RPS6KB2	P05771-2	PRKCB	S410	F404L	404	Missense	distal	-6	no	7.610	7.617	EPSD	ICGC	0.942	Up-regulation
AGC_PKC_PKCa_PRKCB_ST	Q9UBS0	RPS6KB2	P05771-2	PRKCB	S417	V422I	422	Missense	distal	5	no	1.767	1.861	EPSD	ICGC;COSMIC;CCLE	0.942	Up-regulation
AGC_PKC_PKCa_PRKCB_ST	Q9UBS0	RPS6KB2	P05771-2	PRKCB	S417	A420V	420	Missense	distal	3	no	1.767	1.612	EPSD	ICGC;COSMIC	0.942	Down-regulation
AGC_PKC_PKCa_PRKCB_ST	Q9UBS0	RPS6KB2	P05771-2	PRKCB	S436	S438N	438	Missense	proximal	2	no	0.912	1.631	EPSD	ICGC;COSMIC	0.942	Gain
AGC_PKC_PKCa_PRKCB_ST	Q9H1D0	TRPV6	P05771-2	PRKCB	S182	R180W	180	Missense	proximal	-2	no	3.656	0.380	EPSD	ICGC	0.942	Loss
AGC_PKC_PKCa_PRKCB_ST	Q9H1D0	TRPV6	P05771-2	PRKCB	S184	R180W	180	Missense	distal	-4	no	3.920	4.499	PhosphoSitePlus;EPSD	ICGC	0.942	Up-regulation
AGC_PKC_PKCa_PRKCB_ST	P21730	C5AR1	P05771-2	PRKCB	S327	S327F	327	Missense	central	0	yes	1.648	0.000	EPSD	ICGC	0.942	Loss
AGC_PKC_PKCa_PRKCB_ST	P21730	C5AR1	P05771-2	PRKCB	S327	L323F	323	Missense	distal	-4	no	1.648	1.567	EPSD	ICGC;COSMIC	0.942	Down-regulation
AGC_PKC_PKCa_PRKCB_ST	P21730	C5AR1	P05771-2	PRKCB	S332	R337C	337	Missense	distal	5	no	1.111	0.667	EPSD	ICGC;COSMIC;CCLE	0.942	Loss
AGC_PKC_PKCa_PRKCB_ST	P21730	C5AR1	P05771-2	PRKCB	S332	S327F	327	Missense	distal	-5	no	1.111	1.139	EPSD	ICGC	0.942	Up-regulation
AGC_PKC_PKCa_PRKCB_ST	P21730	C5AR1	P05771-2	PRKCB	S334	R337C	337	Missense	distal	3	no	0.990	0.137	PhosphoSitePlus	ICGC;COSMIC;CCLE	0.942	Loss
AGC_PKC_PKCa_PRKCB_ST	P21730	C5AR1	P05771-2	PRKCB	S334	S327F	327	Missense	distal	-7	no	0.990	1.062	PhosphoSitePlus	ICGC	0.942	Up-regulation
AGC_PKC_PKCa_PRKCB_ST	Q14152	EIF3A	P05771-2	PRKCB	T635	E641G	641	Missense	distal	6	no	6.625	5.544	EPSD	ICGC	0.942	Down-regulation
AGC_PKC_PKCa_PRKCB_ST	Q14152	EIF3A	P05771-2	PRKCB	S978	R976C	976	Missense	proximal	-2	no	3.884	2.419	EPSD	ICGC	0.942	Down-regulation
AGC_PKC_PKCa_PRKCB_ST	Q14152	EIF3A	P05771-2	PRKCB	S988	R986Q	986	Missense	proximal	-2	no	3.944	2.973	EPSD	ICGC;COSMIC	0.942	Down-regulation
AGC_PKC_PKCa_PRKCB_ST	Q14152	EIF3A	P05771-2	PRKCB	S1195	R1201Q	1201	Missense	distal	6	no	1.857	1.052	EPSD	ICGC	0.942	Down-regulation
AGC_PKC_PKCa_PRKCB_ST	Q14152	EIF3A	P05771-2	PRKCB	S1263	R1270H	1270	Missense	distal	7	no	6.275	6.501	EPSD	ICGC	0.942	Up-regulation
AGC_PKC_PKCa_PRKCB_ST	Q14152	EIF3A	P05771-2	PRKCB	S1302	P1298L	1298	Missense	distal	-4	no	2.157	2.119	EPSD	ICGC	0.942	Down-regulation
AGC_PKC_PKCa_PRKCB_ST	Q14152	EIF3A	P05771-2	PRKCB	S1302	P1298S	1298	Missense	distal	-4	no	2.157	2.060	EPSD	ICGC	0.942	Down-regulation
AGC_PKC_PKCa_PRKCB_ST	Q14152	EIF3A	P05771-2	PRKCB	S1302	R1295L	1295	Missense	distal	-7	no	2.157	2.421	EPSD	ICGC	0.942	Up-regulation
AGC_PKC_PKCa_PRKCB_ST	P20700	LMNB1	P05771-2	PRKCB	S13	A15S	15	Missense	proximal	2	no	1.855	3.858	EPSD	ICGC	0.942	Up-regulation
AGC_PKC_PKCa_PRKCB_ST	P20700	LMNB1	P05771-2	PRKCB	S13	P6L	6	Missense	distal	-7	no	1.855	1.724	EPSD	ICGC	0.942	Down-regulation
AGC_PKC_PKCa_PRKCB_ST	P20700	LMNB1	P05771-2	PRKCB	S126	A122T	122	Missense	distal	-4	no	2.979	2.874	EPSD	ICGC;COSMIC	0.942	Down-regulation
AGC_PKC_PKCa_PRKCB_ST	P20700	LMNB1	P05771-2	PRKCB	S200	D204Y	204	Missense	distal	4	no	2.652	2.992	EPSD	ICGC;COSMIC	0.942	Up-regulation
AGC_PKC_PKCa_PRKCB_ST	P20700	LMNB1	P05771-2	PRKCB	S200	E203D	203	Missense	distal	3	no	2.652	2.397	EPSD	ICGC	0.942	Down-regulation
AGC_PKC_PKCa_PRKCB_ST	P20700	LMNB1	P05771-2	PRKCB	S232	S232Y	232	Missense	central	0	yes	4.265	0.000	EPSD	ICGC;COSMIC	0.942	Loss
AGC_PKC_PKCa_PRKCB_ST	P20700	LMNB1	P05771-2	PRKCB	S232	E229D	229	Missense	distal	-3	no	4.265	3.470	EPSD	ICGC	0.942	Down-regulation
AGC_PKC_PKCa_PRKCB_ST	P20700	LMNB1	P05771-2	PRKCB	S232	R234L	234	Missense	proximal	2	no	4.265	-2.367	EPSD	ICGC	0.942	Loss
AGC_PKC_PKCa_PRKCB_ST	P20700	LMNB1	P05771-2	PRKCB	S232	L227F	227	Missense	distal	-5	no	4.265	4.300	EPSD	ICGC	0.942	Up-regulation
AGC_PKC_PKCa_PRKCB_ST	P20700	LMNB1	P05771-2	PRKCB	S302	S302I	302	Missense	central	0	yes	2.387	0.000	EPSD	ICGC	0.942	Loss
AGC_PKC_PKCa_PRKCB_ST	P20700	LMNB1	P05771-2	PRKCB	S302	Q306K	306	Missense	distal	4	no	2.387	2.892	EPSD	ICGC;COSMIC	0.942	Up-regulation
AGC_PKC_PKCa_PRKCB_ST	P20700	LMNB1	P05771-2	PRKCB	T340	S335P	335	Missense	distal	-5	no	2.010	1.984	EPSD	ICGC;COSMIC	0.942	Down-regulation
AGC_PKC_PKCa_PRKCB_ST	P20700	LMNB1	P05771-2	PRKCB	T340	D341N	341	Missense	proximal	1	no	2.010	1.007	EPSD	ICGC;COSMIC	0.942	Down-regulation
AGC_PKC_PKCa_PRKCB_ST	P20700	LMNB1	P05771-2	PRKCB	S395	R397H	397	Missense	proximal	2	no	3.812	-2.550	EPSD;PhosphoSitePlus	ICGC	0.942	Loss
AGC_PKC_PKCa_PRKCB_ST	P20700	LMNB1	P05771-2	PRKCB	S395	L388F	388	Missense	distal	-7	no	3.812	3.890	EPSD;PhosphoSitePlus	ICGC	0.942	Up-regulation
AGC_PKC_PKCa_PRKCB_ST	P20700	LMNB1	P05771-2	PRKCB	S395	R397S	397	Missense	proximal	2	no	3.812	-2.185	EPSD;PhosphoSitePlus	ICGC;COSMIC	0.942	Loss
AGC_PKC_PKCa_PRKCB_ST	P20700	LMNB1	P05771-2	PRKCB	T411	K417N	417	Missense	distal	6	no	2.783	2.154	EPSD	ICGC;COSMIC	0.942	Down-regulation
AGC_PKC_PKCa_PRKCB_ST	P20700	LMNB1	P05771-2	PRKCB	T411	R416L	416	Missense	distal	5	no	2.783	2.326	EPSD	ICGC;COSMIC	0.942	Down-regulation
AGC_PKC_PKCa_PRKCB_ST	P20700	LMNB1	P05771-2	PRKCB	T575	L569I	569	Missense	distal	-6	no	1.841	1.893	EPSD	ICGC;COSMIC	0.942	Up-regulation
AGC_PKC_PKCa_PRKCB_ST	P20700	LMNB1	P05771-2	PRKCB	T575	H571N	571	Missense	distal	-4	no	1.841	1.842	EPSD	ICGC;COSMIC	0.942	Up-regulation
AGC_PKC_PKCa_PRKCB_ST	P20700	LMNB1	P05771-2	PRKCB	T575	A578T	578	Missense	distal	3	no	1.841	2.235	EPSD	ICGC;COSMIC	0.942	Up-regulation
AGC_PKC_PKCa_PRKCB_ST	P20700	LMNB1	P05771-2	PRKCB	S579	C583F	583	Missense	distal	4	no	2.788	2.759	EPSD	ICGC	0.942	Down-regulation
AGC_PKC_PKCa_PRKCB_ST	P20700	LMNB1	P05771-2	PRKCB	S579	A578T	578	Missense	proximal	-1	no	2.788	2.942	EPSD	ICGC;COSMIC	0.942	Up-regulation
AGC_PKC_PKCa_PRKCB_ST	Q5T7P8	SYT6	P05771-2	PRKCB	S148	R155C	155	Missense	distal	7	no	3.643	3.840	EPSD	ICGC;COSMIC	0.942	Up-regulation
AGC_PKC_PKCa_PRKCB_ST	Q5T7P8	SYT6	P05771-2	PRKCB	S148	R155H	155	Missense	distal	7	no	3.643	3.870	EPSD	ICGC;COSMIC	0.942	Up-regulation
AGC_PKC_PKCa_PRKCB_ST	Q5T7P8	SYT6	P05771-2	PRKCB	S148	E151D	151	Missense	distal	3	no	3.643	3.389	EPSD	ICGC;COSMIC	0.942	Down-regulation
AGC_PKC_PKCa_PRKCB_ST	Q5T7P8	SYT6	P05771-2	PRKCB	S148	H152N	152	Missense	distal	4	no	3.643	3.775	EPSD	ICGC	0.942	Up-regulation
AGC_PKC_PKCa_PRKCB_ST	Q5T7P8	SYT6	P05771-2	PRKCB	S148	S148L	148	Missense	central	0	yes	3.643	0.000	EPSD	ICGC;COSMIC;CCLE	0.942	Loss
AGC_PKC_PKCa_PRKCB_ST	Q5T7P8	SYT6	P05771-2	PRKCB	S148	M147I	147	Missense	proximal	-1	no	3.643	3.475	EPSD	ICGC;COSMIC	0.942	Down-regulation
AGC_PKC_PKCa_PRKCB_ST	Q5T7P8	SYT6	P05771-2	PRKCB	S169	R171M	171	Missense	proximal	2	no	1.291	-5.470	EPSD	ICGC	0.942	Loss
AGC_PKC_PKCa_PRKCB_ST	Q5T7P8	SYT6	P05771-2	PRKCB	S169	A167E	167	Missense	proximal	-2	no	1.291	1.749	EPSD	ICGC	0.942	Up-regulation
AGC_PKC_PKCa_PRKCB_ST	Q5T7P8	SYT6	P05771-2	PRKCB	S169	A167V	167	Missense	proximal	-2	no	1.291	1.503	EPSD	ICGC	0.942	Up-regulation
AGC_PKC_PKCa_PRKCB_ST	Q5T7P8	SYT6	P05771-2	PRKCB	S216	D221N	221	Missense	distal	5	no	2.342	2.219	EPSD	ICGC;COSMIC	0.942	Down-regulation
AGC_PKC_PKCa_PRKCB_ST	Q5T7P8	SYT6	P05771-2	PRKCB	S216	K223T	223	Missense	distal	7	no	2.342	2.427	EPSD	ICGC	0.942	Up-regulation
AGC_PKC_PKCa_PRKCB_ST	Q5T7P8	SYT6	P05771-2	PRKCB	S216	P209T	209	Missense	distal	-7	no	2.342	2.158	EPSD	ICGC	0.942	Down-regulation
AGC_PKC_PKCa_PRKCB_ST	Q5T7P8	SYT6	P05771-2	PRKCB	S216	L211I	211	Missense	distal	-5	no	2.342	2.424	EPSD	ICGC;COSMIC	0.942	Up-regulation
AGC_PKC_PKCa_PRKCB_ST	Q5T7P8	SYT6	P05771-2	PRKCB	S216	K213N	213	Missense	distal	-3	no	2.342	-0.819	EPSD	ICGC;COSMIC	0.942	Loss
AGC_PKC_PKCa_PRKCB_ST	Q5T7P8	SYT6	P05771-2	PRKCB	T283	H286N	286	Missense	distal	3	no	3.174	3.377	EPSD;PhosphoSitePlus	ICGC;COSMIC	0.942	Up-regulation
AGC_PKC_PKCa_PRKCB_ST	Q5T7P8	SYT6	P05771-2	PRKCB	T283	R287C	287	Missense	distal	4	no	3.174	2.035	EPSD;PhosphoSitePlus	ICGC;COSMIC	0.942	Down-regulation
AGC_PKC_PKCa_PRKCB_ST	Q5T7P8	SYT6	P05771-2	PRKCB	T283	D276N	276	Missense	distal	-7	no	3.174	3.350	EPSD;PhosphoSitePlus	ICGC;COSMIC	0.942	Up-regulation
AGC_PKC_PKCa_PRKCB_ST	Q5T7P8	SYT6	P05771-2	PRKCB	T283	R287H	287	Missense	distal	4	no	3.174	2.352	EPSD;PhosphoSitePlus	ICGC;COSMIC	0.942	Down-regulation
AGC_PKC_PKCa_PRKCB_ST	Q5T7P8	SYT6	P05771-2	PRKCB	T283	L281M	281	Missense	proximal	-2	no	3.174	3.655	EPSD;PhosphoSitePlus	ICGC;COSMIC	0.942	Up-regulation
AGC_PKC_PKCa_PRKCB_ST	Q5T7P8	SYT6	P05771-2	PRKCB	T283	C279G	279	Missense	distal	-4	no	3.174	3.086	EPSD;PhosphoSitePlus	ICGC;COSMIC	0.942	Down-regulation
AGC_PKC_PKCa_PRKCB_ST	Q5T7P8	SYT6	P05771-2	PRKCB	T283	H286P	286	Missense	distal	3	no	3.174	3.281	EPSD;PhosphoSitePlus	ICGC;COSMIC	0.942	Up-regulation
AGC_PKC_PKCa_PRKCB_ST	Q5T7P8	SYT6	P05771-2	PRKCB	T283	R277H	277	Missense	distal	-6	no	3.174	2.929	EPSD;PhosphoSitePlus	ICGC;COSMIC	0.942	Down-regulation
AGC_PKC_PKCa_PRKCB_ST	Q5T7P8	SYT6	P05771-2	PRKCB	T417	N422K	422	Missense	distal	5	no	2.583	2.956	EPSD;PhosphoSitePlus	ICGC	0.942	Up-regulation
AGC_PKC_PKCa_PRKCB_ST	Q5T7P8	SYT6	P05771-2	PRKCB	T417	L412M	412	Missense	distal	-5	no	2.583	2.592	EPSD;PhosphoSitePlus	ICGC	0.942	Up-regulation
AGC_PKC_PKCa_PRKCB_ST	Q5T7P8	SYT6	P05771-2	PRKCB	T417	L424R	424	Missense	distal	7	no	2.583	2.353	EPSD;PhosphoSitePlus	ICGC;COSMIC	0.942	Down-regulation
AGC_PKC_PKCa_PRKCB_ST	Q5T7P8	SYT6	P05771-2	PRKCB	T418	N422K	422	Missense	distal	4	no	5.603	6.178	PhosphoSitePlus;EPSD	ICGC	0.942	Up-regulation
AGC_PKC_PKCa_PRKCB_ST	Q5T7P8	SYT6	P05771-2	PRKCB	T418	L412M	412	Missense	distal	-6	no	5.603	5.661	PhosphoSitePlus;EPSD	ICGC	0.942	Up-regulation
AGC_PKC_PKCa_PRKCB_ST	Q5T7P8	SYT6	P05771-2	PRKCB	T418	L424R	424	Missense	distal	6	no	5.603	6.861	PhosphoSitePlus;EPSD	ICGC;COSMIC	0.942	Up-regulation
AGC_PKC_PKCa_PRKCB_ST	Q04637	EIF4G1	P05771-2	PRKCB	S45	A38S	38	Missense	distal	-7	no	1.205	1.235	EPSD	ICGC	0.942	Up-regulation
AGC_PKC_PKCa_PRKCB_ST	Q04637	EIF4G1	P05771-2	PRKCB	S45	S45F	45	Missense	central	0	yes	1.205	0.000	EPSD	ICGC;COSMIC	0.942	Loss
AGC_PKC_PKCa_PRKCB_ST	Q04637	EIF4G1	P05771-2	PRKCB	S204	P208S	208	Missense	distal	4	no	3.028	2.893	EPSD	ICGC;COSMIC	0.942	Down-regulation
AGC_PKC_PKCa_PRKCB_ST	Q04637	EIF4G1	P05771-2	PRKCB	S204	P208H	208	Missense	distal	4	no	3.028	3.089	EPSD	ICGC;GDSC;CCLE	0.942	Up-regulation
AGC_PKC_PKCa_PRKCB_ST	Q04637	EIF4G1	P05771-2	PRKCB	T1182	R1184Q	1184	Missense	proximal	2	no	2.924	-3.625	EPSD	ICGC;COSMIC	0.942	Loss
AGC_PKC_PKCa_PRKCB_ST	Q04637	EIF4G1	P05771-2	PRKCB	S1185	R1184Q	1184	Missense	proximal	-1	no	1.016	0.831	EPSD	ICGC;COSMIC	0.942	Loss
AGC_PKC_PKCa_PRKCB_ST	Q04637	EIF4G1	P05771-2	PRKCB	S1209	E1212Q	1212	Missense	distal	3	no	2.740	2.580	EPSD	ICGC;COSMIC	0.942	Down-regulation
AGC_PKC_PKCa_PRKCB_ST	Q04637	EIF4G1	P05771-2	PRKCB	S1209	E1202D	1202	Missense	distal	-7	no	2.740	2.662	EPSD	ICGC	0.942	Down-regulation
AGC_PKC_PKCa_PRKCB_ST	O15350	TP73	P05771-2	PRKCB	S235	G232S	232	Missense	distal	-3	no	0.758	1.577	EPSD	ICGC;COSMIC	0.942	Gain
AGC_PKC_PKCa_PRKCB_ST	O15350	TP73	P05771-2	PRKCB	S326	G323R	323	Missense	distal	-3	no	6.967	11.183	EPSD	ICGC;COSMIC	0.942	Up-regulation
AGC_PKC_PKCa_PRKCB_ST	O15350	TP73	P05771-2	PRKCB	S326	K331N	331	Missense	distal	5	no	6.967	6.594	EPSD	ICGC	0.942	Down-regulation
AGC_PKC_PKCa_PRKCB_ST	O15350	TP73	P05771-2	PRKCB	S388	R390L	390	Missense	proximal	2	no	2.009	-4.623	PhosphoSitePlus	ICGC;COSMIC	0.942	Loss
AGC_PKC_PKCa_PRKCB_ST	O15350	TP73	P05771-2	PRKCB	S426	M421I	421	Missense	distal	-5	no	3.051	3.124	EPSD	ICGC;COSMIC	0.942	Up-regulation
AGC_PKC_PKCa_PRKCB_ST	O15350	TP73	P05771-2	PRKCB	S426	G432V	432	Missense	distal	6	no	3.051	3.225	EPSD	ICGC	0.942	Up-regulation
AGC_PKC_PKCa_PRKCB_ST	O15350	TP73	P05771-2	PRKCB	S426	G432D	432	Missense	distal	6	no	3.051	3.732	EPSD	ICGC;COSMIC;GDSC;CCLE	0.942	Up-regulation
AGC_PKC_PKCa_PRKCB_ST	P28329	CHAT	P05771-2	PRKCB	S594	L597F	597	Missense	distal	3	no	2.132	2.190	EPSD	ICGC;COSMIC	0.942	Up-regulation
AGC_PKC_PKCa_PRKCB_ST	P28329	CHAT	P05771-2	PRKCB	S594	A590T	590	Missense	distal	-4	no	2.132	2.027	EPSD	ICGC;COSMIC	0.942	Down-regulation
AGC_PKC_PKCa_PRKCB_ST	P35637	FUS	P05771-2	PRKCB	S257	G252V	252	Missense	distal	-5	no	4.568	4.587	PhosphoSitePlus	ICGC	0.942	Up-regulation
AGC_PKC_PKCa_PRKCB_ST	P35637	FUS	P05771-2	PRKCB	S277	D276E	276	Missense	proximal	-1	no	1.565	1.652	EPSD	ICGC;COSMIC	0.942	Up-regulation
AGC_PKC_PKCa_PRKCB_ST	Q9UBU3	GHRL	P05771-2	PRKCB	S41	Q36H	36	Missense	distal	-5	no	9.523	9.293	PhosphoSitePlus	ICGC;COSMIC	0.942	Down-regulation
AGC_PKC_PKCa_PRKCB_ST	P49840	GSK3A	P05771-2	PRKCB	S97	G98R	98	Missense	proximal	1	no	0.435	2.545	EPSD	ICGC	0.942	Gain
AGC_PKC_PKCa_PRKCB_ST	P49840	GSK3A	P05771-2	PRKCB	S266	L259P	259	Missense	distal	-7	no	2.948	3.079	EPSD	ICGC;COSMIC	0.942	Up-regulation
TK_Syk_SYK_Y	P02730	SLC4A1	P43405	SYK	Y21	Q18H	18	Missense	distal	-3	no	26.467	27.532	EPSD;PhosphoSitePlus	ICGC;COSMIC	13.041	Up-regulation
TK_Syk_SYK_Y	P02730	SLC4A1	P43405	SYK	Y21	P27L	27	Missense	distal	6	no	26.467	26.062	EPSD;PhosphoSitePlus	ICGC;COSMIC	13.041	Down-regulation
TK_Syk_SYK_Y	P02730	SLC4A1	P43405	SYK	Y904	P910T	910	Missense	distal	6	no	22.145	22.128	PhosphoSitePlus;EPSD	ICGC	13.041	Down-regulation
TK_Syk_SYK_Y	P02730	SLC4A1	P43405	SYK	Y904	A908V	908	Missense	distal	4	no	22.145	21.925	PhosphoSitePlus;EPSD	ICGC	13.041	Down-regulation
TK_Syk_SYK_Y	Q8IWV1	LAX1	P43405	SYK	Y193	E188D	188	Missense	distal	-5	no	21.486	21.665	EPSD;PhosphoSitePlus	ICGC;COSMIC	13.041	Up-regulation
TK_Syk_SYK_Y	P19174	PLCG1	P43405	SYK	Y210	G206E	206	Missense	distal	-4	no	12.743	13.942	EPSD	ICGC	13.041	Gain
TK_Syk_SYK_Y	P19174	PLCG1	P43405	SYK	Y472	K465N	465	Missense	distal	-7	no	16.799	16.658	EPSD	ICGC	13.041	Down-regulation
TK_Syk_SYK_Y	P19174	PLCG1	P43405	SYK	Y771	R778H	778	Missense	distal	7	no	17.856	18.027	PhosphoSitePlus;EPSD	ICGC;COSMIC	13.041	Up-regulation
TK_Syk_SYK_Y	P19174	PLCG1	P43405	SYK	Y771	G772E	772	Missense	proximal	1	no	17.856	21.107	PhosphoSitePlus;EPSD	ICGC	13.041	Up-regulation
TK_Syk_SYK_Y	P19174	PLCG1	P43405	SYK	Y771	A767V	767	Missense	distal	-4	no	17.856	17.203	PhosphoSitePlus;EPSD	ICGC;COSMIC	13.041	Down-regulation
TK_Syk_SYK_Y	P19174	PLCG1	P43405	SYK	Y775	G772E	772	Missense	distal	-3	no	12.653	15.310	EPSD	ICGC	13.041	Gain
TK_Syk_SYK_Y	P19174	PLCG1	P43405	SYK	Y783	R778H	778	Missense	distal	-5	no	15.446	15.611	EPSD;PhosphoSitePlus	ICGC;COSMIC	13.041	Up-regulation
TK_Syk_SYK_Y	P19174	PLCG1	P43405	SYK	Y1196	D1199V	1199	Missense	distal	3	no	10.649	13.426	EPSD	ICGC	13.041	Gain
TK_Syk_SYK_Y	Q8WV28	BLNK	P43405	SYK	Y84	V85A	85	Missense	proximal	1	no	22.896	19.878	EPSD;PhosphoSitePlus	ICGC;COSMIC	13.041	Down-regulation
TK_Syk_SYK_Y	Q8WV28	BLNK	P43405	SYK	Y84	N91K	91	Missense	distal	7	no	22.896	22.779	EPSD;PhosphoSitePlus	ICGC;COSMIC	13.041	Down-regulation
TK_Syk_SYK_Y	Q8WV28	BLNK	P43405	SYK	Y84	E90K	90	Missense	distal	6	no	22.896	22.472	EPSD;PhosphoSitePlus	ICGC	13.041	Down-regulation
TK_Syk_SYK_Y	Q8WV28	BLNK	P43405	SYK	Y96	N91K	91	Missense	distal	-5	no	27.373	27.070	PhosphoSitePlus;EPSD	ICGC;COSMIC	13.041	Down-regulation
TK_Syk_SYK_Y	Q8WV28	BLNK	P43405	SYK	Y96	E90K	90	Missense	distal	-6	no	27.373	26.541	PhosphoSitePlus;EPSD	ICGC	13.041	Down-regulation
TK_Syk_SYK_Y	P16885	PLCG2	P43405	SYK	Y680	A686D	686	Missense	distal	6	no	12.648	13.143	EPSD	ICGC;COSMIC	13.041	Gain
TK_Syk_SYK_Y	P16885	PLCG2	P43405	SYK	Y759	P762H	762	Missense	distal	3	no	16.328	10.814	PhosphoSitePlus	ICGC;COSMIC	13.041	Loss
TK_Syk_SYK_Y	P16885	PLCG2	P43405	SYK	Y811	G804R	804	Missense	distal	-7	no	13.402	13.052	EPSD	ICGC;COSMIC	13.041	Down-regulation
TK_Syk_SYK_Y	P16885	PLCG2	P43405	SYK	Y811	R814S	814	Missense	distal	3	no	13.402	13.387	EPSD	ICGC	13.041	Down-regulation
TK_Syk_SYK_Y	P16885	PLCG2	P43405	SYK	Y1048	P1052L	1052	Missense	distal	4	no	16.841	15.864	EPSD	ICGC	13.041	Down-regulation
TK_Syk_SYK_Y	P14317	HCLS1	P43405	SYK	Y397	P403T	403	Missense	distal	6	no	29.543	29.526	EPSD;PhosphoSitePlus	ICGC	13.041	Down-regulation
TK_Syk_SYK_Y	P12318	FCGR2A	P43405	SYK	Y281	L274P	274	Missense	distal	-7	no	23.005	23.271	EPSD;PhosphoSitePlus	ICGC;COSMIC	13.041	Up-regulation
TK_Syk_SYK_Y	P12318	FCGR2A	P43405	SYK	Y281	Y288F	288	Missense	distal	7	no	23.005	22.566	EPSD;PhosphoSitePlus	ICGC;COSMIC	13.041	Down-regulation
TK_Syk_SYK_Y	P12318	FCGR2A	P43405	SYK	Y288	Y288F	288	Missense	central	0	yes	15.595	0.000	EPSD	ICGC;COSMIC	13.041	Loss
TK_Syk_SYK_Y	P12318	FCGR2A	P43405	SYK	Y288	P293H	293	Missense	distal	5	no	15.595	15.640	EPSD	ICGC;COSMIC	13.041	Up-regulation
TK_Syk_SYK_Y	P12318	FCGR2A	P43405	SYK	Y304	D298N	298	Missense	distal	-6	no	15.344	14.895	PhosphoSitePlus;EPSD	ICGC;COSMIC	13.041	Down-regulation
TK_Syk_SYK_Y	P12318	FCGR2A	P43405	SYK	Y304	D299N	299	Missense	distal	-5	no	15.344	14.814	PhosphoSitePlus;EPSD	ICGC;COSMIC	13.041	Down-regulation
TK_Syk_SYK_Y	Q13422	IKZF1	P43405	SYK	Y293	T291M	291	Missense	proximal	-2	no	15.490	14.486	EPSD	ICGC;COSMIC	13.041	Down-regulation
TK_Syk_SYK_Y	Q9GZY6	LAT2	P43405	SYK	Y110	S106P	106	Missense	distal	-4	no	20.418	19.747	EPSD	ICGC;COSMIC	13.041	Down-regulation
TK_Syk_SYK_Y	Q9GZY6	LAT2	P43405	SYK	Y110	A115S	115	Missense	distal	5	no	20.418	20.208	EPSD	ICGC	13.041	Down-regulation
TK_Syk_SYK_Y	Q9GZY6	LAT2	P43405	SYK	Y136	E137K	137	Missense	proximal	1	no	21.870	18.389	EPSD;PhosphoSitePlus	ICGC;COSMIC	13.041	Down-regulation
TK_Syk_SYK_Y	Q9GZY6	LAT2	P43405	SYK	Y136	D130H	130	Missense	distal	-6	no	21.870	21.043	EPSD;PhosphoSitePlus	ICGC;COSMIC	13.041	Down-regulation
TK_Syk_SYK_Y	Q9GZY6	LAT2	P43405	SYK	Y136	E129Q	129	Missense	distal	-7	no	21.870	20.783	EPSD;PhosphoSitePlus	ICGC;COSMIC	13.041	Down-regulation
TK_Syk_SYK_Y	Q14247	CTTN	P43405	SYK	Y228	G233E	233	Missense	distal	5	no	13.148	12.933	EPSD	ICGC;COSMIC	13.041	Loss
TK_Syk_SYK_Y	Q14247	CTTN	P43405	SYK	Y228	G231R	231	Missense	distal	3	no	13.148	14.445	EPSD	ICGC	13.041	Up-regulation
TK_Syk_SYK_Y	Q14247	CTTN	P43405	SYK	Y421	L415P	415	Missense	distal	-6	no	19.566	20.041	PhosphoSitePlus	ICGC	13.041	Up-regulation
TK_Syk_SYK_Y	Q14247	CTTN	P43405	SYK	Y421	A424V	424	Missense	distal	3	no	19.566	18.788	PhosphoSitePlus	ICGC;COSMIC;GDSC	13.041	Down-regulation
TK_Syk_SYK_Y	Q14247	CTTN	P43405	SYK	Y433	T440M	440	Missense	distal	7	no	13.165	13.055	EPSD	ICGC	13.041	Down-regulation
TK_Syk_SYK_Y	Q14247	CTTN	P43405	SYK	Y433	S438I	438	Missense	distal	5	no	13.165	13.266	EPSD	ICGC	13.041	Up-regulation
TK_Syk_SYK_Y	Q14247	CTTN	P43405	SYK	Y453	A450G	450	Missense	distal	-3	no	14.082	16.508	EPSD	ICGC;COSMIC	13.041	Up-regulation
TK_Syk_SYK_Y	Q14247	CTTN	P43405	SYK	Y453	R454Q	454	Missense	proximal	1	no	14.082	14.001	EPSD	ICGC	13.041	Down-regulation
TK_Syk_SYK_Y	Q14247	CTTN	P43405	SYK	Y453	A450V	450	Missense	distal	-3	no	14.082	14.430	EPSD	ICGC;COSMIC	13.041	Up-regulation
TK_Syk_SYK_Y	Q14247	CTTN	P43405	SYK	Y470	A463P	463	Missense	distal	-7	no	16.470	16.871	EPSD	ICGC;COSMIC	13.041	Up-regulation
TK_Syk_SYK_Y	Q14247	CTTN	P43405	SYK	Y470	P476S	476	Missense	distal	6	no	16.470	16.615	EPSD	ICGC;COSMIC	13.041	Up-regulation
TK_Syk_SYK_Y	Q14247	CTTN	P43405	SYK	Y486	D483N	483	Missense	distal	-3	no	16.556	14.075	EPSD	ICGC;COSMIC	13.041	Down-regulation
TK_Syk_SYK_Y	Q14247	CTTN	P43405	SYK	Y486	D487N	487	Missense	proximal	1	no	16.556	15.237	EPSD	ICGC;COSMIC;GDSC	13.041	Down-regulation
TK_Syk_SYK_Y	Q14247	CTTN	P43405	SYK	Y486	P480A	480	Missense	distal	-6	no	16.556	16.296	EPSD	ICGC;COSMIC	13.041	Down-regulation
TK_Syk_SYK_Y	Q14247	CTTN	P43405	SYK	Y486	D492Y	492	Missense	distal	6	no	16.556	16.064	EPSD	ICGC;COSMIC	13.041	Down-regulation
TK_Syk_SYK_Y	Q14247	CTTN	P43405	SYK	Y486	D492H	492	Missense	distal	6	no	16.556	16.193	EPSD	ICGC;COSMIC	13.041	Down-regulation
TK_Syk_SYK_Y	Q14247	CTTN	P43405	SYK	Y486	P480S	480	Missense	distal	-6	no	16.556	17.022	EPSD	ICGC;COSMIC	13.041	Up-regulation
TK_Syk_SYK_Y	Q14247	CTTN	P43405	SYK	Y486	L493M	493	Missense	distal	7	no	16.556	17.133	EPSD	ICGC;COSMIC	13.041	Up-regulation
TK_Syk_SYK_Y	P52566	ARHGDIB	P43405	SYK	Y24	P26H	26	Missense	proximal	2	no	17.657	17.960	PhosphoSitePlus	ICGC	13.041	Up-regulation
TK_Syk_SYK_Y	P52566	ARHGDIB	P43405	SYK	Y146	G144C	144	Missense	proximal	-2	no	13.420	10.992	EPSD	ICGC;COSMIC	13.041	Loss
TK_Syk_SYK_Y	P52566	ARHGDIB	P43405	SYK	Y146	E151D	151	Missense	distal	5	no	13.420	13.532	EPSD	ICGC	13.041	Up-regulation
TK_Syk_SYK_Y	P52566	ARHGDIB	P43405	SYK	Y153	F155L	155	Missense	proximal	2	no	14.241	13.912	EPSD	ICGC;COSMIC	13.041	Down-regulation
TK_Syk_SYK_Y	P52566	ARHGDIB	P43405	SYK	Y153	E151D	151	Missense	proximal	-2	no	14.241	15.047	EPSD	ICGC	13.041	Up-regulation
TK_Syk_SYK_Y	P42229	STAT5A	P43405	SYK	Y720	G714W	714	Missense	distal	-6	no	13.328	12.283	EPSD	ICGC;COSMIC	13.041	Loss
TK_Syk_SYK_Y	P22681	CBL	P43405	SYK	Y141	G136V	136	Missense	distal	-5	no	18.842	18.539	EPSD	ICGC	13.041	Down-regulation
TK_Syk_SYK_Y	P22681	CBL	P43405	SYK	Y455	D459V	459	Missense	distal	4	no	16.274	15.367	EPSD	ICGC;COSMIC	13.041	Down-regulation
TK_Syk_SYK_Y	P22681	CBL	P43405	SYK	Y700	M701L	701	Missense	proximal	1	no	20.796	20.659	PhosphoSitePlus;EPSD	ICGC;COSMIC	13.041	Down-regulation
TK_Syk_SYK_Y	P22681	CBL	P43405	SYK	Y700	E696D	696	Missense	distal	-4	no	20.796	22.074	PhosphoSitePlus;EPSD	ICGC;COSMIC	13.041	Up-regulation
TK_Syk_SYK_Y	P22681	CBL	P43405	SYK	Y700	E693D	693	Missense	distal	-7	no	20.796	20.373	PhosphoSitePlus;EPSD	ICGC;COSMIC	13.041	Down-regulation
TK_Syk_SYK_Y	P22681	CBL	P43405	SYK	Y731	Y731H	731	Missense	central	0	yes	19.225	0.000	EPSD;PhosphoSitePlus	ICGC;COSMIC	13.041	Loss
TK_Syk_SYK_Y	P22681	CBL	P43405	SYK	Y774	G773E	773	Missense	proximal	-1	no	27.322	29.029	EPSD;PhosphoSitePlus	ICGC	13.041	Up-regulation
TK_Syk_SYK_Y	P37840	SNCA	P43405	SYK	Y125	P120T	120	Missense	distal	-5	no	26.604	26.723	EPSD;PhosphoSitePlus	ICGC	13.041	Up-regulation
TK_Syk_SYK_Y	P37840	SNCA	P43405	SYK	Y133	Q134K	134	Missense	proximal	1	no	19.060	21.351	PhosphoSitePlus;EPSD	ICGC;COSMIC	13.041	Up-regulation
TK_Syk_SYK_Y	P37840	SNCA	P43405	SYK	Y136	Q134K	134	Missense	proximal	-2	no	20.521	21.579	EPSD;PhosphoSitePlus	ICGC;COSMIC	13.041	Up-regulation
TK_Syk_SYK_Y	P51452	DUSP3	P43405	SYK	Y23	S20R	20	Missense	distal	-3	no	14.301	11.594	EPSD	ICGC;COSMIC	13.041	Loss
TK_Syk_SYK_Y	P51452	DUSP3	P43405	SYK	Y23	C30R	30	Missense	distal	7	no	14.301	14.559	EPSD	ICGC;COSMIC	13.041	Up-regulation
TK_Syk_SYK_Y	P43405	SYK	P43405	SYK	Y28	Y28D	28	Missense	central	0	yes	17.283	0.000	EPSD	ICGC;COSMIC	13.041	Loss
TK_Syk_SYK_Y	P43405	SYK	P43405	SYK	Y28	S35I	35	Missense	distal	7	no	17.283	17.045	EPSD	ICGC	13.041	Down-regulation
TK_Syk_SYK_Y	P43405	SYK	P43405	SYK	Y28	L29V	29	Missense	proximal	1	no	17.283	19.238	EPSD	ICGC;COSMIC	13.041	Up-regulation
TK_Syk_SYK_Y	P43405	SYK	P43405	SYK	Y28	G33S	33	Missense	distal	5	no	17.283	17.260	EPSD	ICGC;COSMIC	13.041	Down-regulation
TK_Syk_SYK_Y	Q06187	BTK	P43405	SYK	Y225	A221D	221	Missense	distal	-4	no	11.536	14.168	EPSD	ICGC	13.041	Gain
TK_Syk_SYK_Y	Q06187	BTK	P43405	SYK	Y241	F242Y	242	Missense	proximal	1	no	10.826	13.594	EPSD	ICGC;COSMIC	13.041	Gain
TK_Syk_SYK_Y	Q06187	BTK	P43405	SYK	Y511	A508D	508	Missense	distal	-3	no	8.585	14.359	EPSD	ICGC;COSMIC	13.041	Gain
TK_Syk_SYK_Y	Q06187	BTK	P43405	SYK	Y551	K558T	558	Missense	distal	7	no	15.858	15.842	PhosphoSitePlus	ICGC	13.041	Down-regulation
TK_Syk_SYK_Y	Q8N6F7	GCSAM	P43405	SYK	Y80	D74N	74	Missense	distal	-6	no	13.551	13.102	EPSD	ICGC;COSMIC	13.041	Down-regulation
TK_Syk_SYK_Y	Q8N6F7	GCSAM	P43405	SYK	Y80	E82D	82	Missense	proximal	2	no	13.551	14.613	EPSD	ICGC;COSMIC	13.041	Up-regulation
TK_Syk_SYK_Y	Q8N6F7	GCSAM	P43405	SYK	Y80	T87I	87	Missense	distal	7	no	13.551	13.326	EPSD	ICGC;COSMIC	13.041	Down-regulation
TK_Syk_SYK_Y	Q8N6F7	GCSAM	P43405	SYK	Y107	E108D	108	Missense	proximal	1	no	22.062	18.421	EPSD;PhosphoSitePlus	ICGC;COSMIC	13.041	Down-regulation
TK_Syk_SYK_Y	Q8N6F7	GCSAM	P43405	SYK	Y107	P111S	111	Missense	distal	4	no	22.062	22.004	EPSD;PhosphoSitePlus	ICGC	13.041	Down-regulation
TK_Syk_SYK_Y	Q8N6F7	GCSAM	P43405	SYK	Y107	A114V	114	Missense	distal	7	no	22.062	22.105	EPSD;PhosphoSitePlus	ICGC	13.041	Up-regulation
TK_Syk_SYK_Y	Q8N6F7	GCSAM	P43405	SYK	Y128	G123E	123	Missense	distal	-5	no	14.817	15.403	PhosphoSitePlus;EPSD	ICGC;COSMIC;GDSC	13.041	Up-regulation
TK_Syk_SYK_Y	Q8N6F7	GCSAM	P43405	SYK	Y128	G123R	123	Missense	distal	-5	no	14.817	14.470	PhosphoSitePlus;EPSD	ICGC;COSMIC	13.041	Down-regulation
TK_Syk_SYK_Y	Q8N6F7	GCSAM	P43405	SYK	Y148	E145K	145	Missense	distal	-3	no	20.333	17.454	EPSD	ICGC	13.041	Down-regulation
TK_Syk_SYK_Y	Q8N6F7	GCSAM	P43405	SYK	Y148	R155K	155	Missense	distal	7	no	20.333	20.583	EPSD	ICGC;COSMIC	13.041	Up-regulation
TK_Syk_SYK_Y	P10636	MAPT	P43405	SYK	Y18	A15T	15	Missense	distal	-3	no	12.216	14.482	PhosphoSitePlus	ICGC;COSMIC	13.041	Gain
TK_Syk_SYK_Y	P10636	MAPT	P43405	SYK	Y514	G521R	521	Missense	distal	7	no	18.664	18.573	EPSD	ICGC;COSMIC	13.041	Down-regulation
TK_Syk_SYK_Y	Q13094	LCP2	P43405	SYK	Y113	P116H	116	Missense	distal	3	no	26.457	20.942	PhosphoSitePlus;EPSD	ICGC	13.041	Down-regulation
TK_Syk_SYK_Y	Q13094	LCP2	P43405	SYK	Y128	S130F	130	Missense	proximal	2	no	32.230	29.256	EPSD;PhosphoSitePlus	ICGC	13.041	Down-regulation
TK_Syk_SYK_Y	Q13094	LCP2	P43405	SYK	Y128	G122W	122	Missense	distal	-6	no	32.230	31.185	EPSD;PhosphoSitePlus	ICGC;COSMIC	13.041	Down-regulation
TK_Syk_SYK_Y	Q13094	LCP2	P43405	SYK	Y145	P147L	147	Missense	proximal	2	no	28.463	26.341	EPSD	ICGC;COSMIC	13.041	Down-regulation
TK_Syk_SYK_Y	Q13094	LCP2	P43405	SYK	Y173	S179P	179	Missense	distal	6	no	14.138	13.993	EPSD	ICGC;COSMIC	13.041	Down-regulation
TK_Syk_SYK_Y	Q13094	LCP2	P43405	SYK	Y173	P167L	167	Missense	distal	-6	no	14.138	13.663	EPSD	ICGC;COSMIC	13.041	Down-regulation
TK_Syk_SYK_Y	Q13094	LCP2	P43405	SYK	Y173	D175N	175	Missense	proximal	2	no	14.138	12.049	EPSD	ICGC;COSMIC	13.041	Loss
TK_Syk_SYK_Y	Q13094	LCP2	P43405	SYK	Y423	S425Y	425	Missense	proximal	2	no	18.723	16.907	EPSD	ICGC;COSMIC	13.041	Down-regulation
TK_Syk_SYK_Y	Q13094	LCP2	P43405	SYK	Y423	R429L	429	Missense	distal	6	no	18.723	18.393	EPSD	ICGC;COSMIC	13.041	Down-regulation
TK_Syk_SYK_Y	Q13094	LCP2	P43405	SYK	Y423	V424I	424	Missense	proximal	1	no	18.723	17.500	EPSD	ICGC	13.041	Down-regulation
STE_STE20_FRAY_STK39_ST	Q13621	SLC12A1	Q9UEW8	STK39	T95	G102C	102	Missense	distal	7	no	174.299	174.290	EPSD;PhosphoSitePlus	ICGC;COSMIC	61.825	Down-regulation
STE_STE20_FRAY_STK39_ST	Q13621	SLC12A1	Q9UEW8	STK39	T100	D107Y	107	Missense	distal	7	no	176.343	176.305	EPSD;PhosphoSitePlus	ICGC	61.825	Down-regulation
STE_STE20_FRAY_STK39_ST	Q13621	SLC12A1	Q9UEW8	STK39	T100	G102C	102	Missense	proximal	2	no	176.343	176.136	EPSD;PhosphoSitePlus	ICGC;COSMIC	61.825	Down-regulation
STE_STE20_FRAY_STK39_ST	Q13621	SLC12A1	Q9UEW8	STK39	T105	D107Y	107	Missense	proximal	2	no	157.976	141.464	PhosphoSitePlus;EPSD	ICGC	61.825	Down-regulation
STE_STE20_FRAY_STK39_ST	Q13621	SLC12A1	Q9UEW8	STK39	T105	G102C	102	Missense	distal	-3	no	157.976	158.761	PhosphoSitePlus;EPSD	ICGC;COSMIC	61.825	Up-regulation
STE_STE20_FRAY_STK39_ST	Q13621	SLC12A1	Q9UEW8	STK39	T118	E113D	113	Missense	distal	-5	no	43.120	74.626	EPSD	ICGC	61.825	Gain
STE_STE20_FRAY_STK39_ST	Q13621	SLC12A1	Q9UEW8	STK39	S120	E113D	113	Missense	distal	-7	no	64.347	62.530	EPSD	ICGC	61.825	Down-regulation
STE_STE20_FRAY_STK39_ST	Q13621	SLC12A1	Q9UEW8	STK39	S120	S120I	120	Missense	central	0	yes	64.347	0.000	EPSD	ICGC	61.825	Loss
STE_STE20_FRAY_STK39_ST	Q13621	SLC12A1	Q9UEW8	STK39	S120	P124T	124	Missense	distal	4	no	64.347	74.448	EPSD	ICGC;COSMIC	61.825	Up-regulation
STE_STE20_FRAY_STK39_ST	Q13621	SLC12A1	Q9UEW8	STK39	S120	R116H	116	Missense	distal	-4	no	64.347	77.575	EPSD	ICGC;COSMIC;GDSC	61.825	Up-regulation
STE_STE20_FRAY_STK39_ST	Q13621	SLC12A1	Q9UEW8	STK39	S120	G123E	123	Missense	distal	3	no	64.347	64.674	EPSD	ICGC	61.825	Up-regulation
STE_STE20_FRAY_STK39_ST	Q13621	SLC12A1	Q9UEW8	STK39	T145	L138I	138	Missense	distal	-7	no	90.681	89.149	EPSD	ICGC	61.825	Down-regulation
STE_STE20_FRAY_STK39_ST	Q13621	SLC12A1	Q9UEW8	STK39	T145	T145A	145	Missense	central	0	yes	90.681	0.000	EPSD	ICGC;COSMIC	61.825	Loss
STE_STE20_FRAY_STK39_ST	Q13621	SLC12A1	Q9UEW8	STK39	T145	A139T	139	Missense	distal	-6	no	90.681	83.915	EPSD	ICGC;COSMIC;GDSC	61.825	Down-regulation
STE_STE20_FRAY_STK39_ST	Q13621	SLC12A1	Q9UEW8	STK39	T882	K875E	875	Missense	distal	-7	no	131.807	133.490	EPSD	ICGC;COSMIC	61.825	Up-regulation
STE_STE20_FRAY_STK39_ST	Q9Y6R1	SLC4A4	Q9UEW8	STK39	T28	I29T	29	Missense	proximal	1	no	88.857	81.212	EPSD	ICGC;COSMIC	61.825	Down-regulation
STE_STE20_FRAY_STK39_ST	Q9Y6R1	SLC4A4	Q9UEW8	STK39	S38	R44C	44	Missense	distal	6	no	82.066	80.856	EPSD	ICGC	61.825	Down-regulation
STE_STE20_FRAY_STK39_ST	Q9Y6R1	SLC4A4	Q9UEW8	STK39	T49	H51N	51	Missense	proximal	2	no	94.930	87.755	EPSD	ICGC;COSMIC	61.825	Down-regulation
STE_STE20_FRAY_STK39_ST	Q9Y6R1	SLC4A4	Q9UEW8	STK39	T49	G50E	50	Missense	proximal	1	no	94.930	93.109	EPSD	ICGC;COSMIC	61.825	Down-regulation
STE_STE20_FRAY_STK39_ST	Q9Y6R1	SLC4A4	Q9UEW8	STK39	T49	R44C	44	Missense	distal	-5	no	94.930	106.866	EPSD	ICGC	61.825	Up-regulation
STE_STE20_FRAY_STK39_ST	Q9Y6R1	SLC4A4	Q9UEW8	STK39	T230	M237I	237	Missense	distal	7	no	77.218	77.219	EPSD	ICGC;COSMIC	61.825	Up-regulation
STE_STE20_FRAY_STK39_ST	Q9Y6R1	SLC4A4	Q9UEW8	STK39	T230	G228W	228	Missense	proximal	-2	no	77.218	85.078	EPSD	ICGC;COSMIC	61.825	Up-regulation
STE_STE20_FRAY_STK39_ST	Q9Y6R1	SLC4A4	Q9UEW8	STK39	T230	D226N	226	Missense	distal	-4	no	77.218	70.655	EPSD	ICGC	61.825	Down-regulation
STE_STE20_FRAY_STK39_ST	Q9Y6R1	SLC4A4	Q9UEW8	STK39	S235	M237I	237	Missense	proximal	2	no	60.739	63.754	EPSD	ICGC;COSMIC	61.825	Gain
STE_STE20_FRAY_STK39_ST	Q9Y6R1	SLC4A4	Q9UEW8	STK39	T239	M237I	237	Missense	proximal	-2	no	65.823	62.129	EPSD	ICGC;COSMIC	61.825	Down-regulation
STE_STE20_FRAY_STK39_ST	Q9Y6R1	SLC4A4	Q9UEW8	STK39	T249	S255F	255	Missense	distal	6	no	77.158	78.323	EPSD	ICGC;COSMIC	61.825	Up-regulation
STE_STE20_FRAY_STK39_ST	Q9Y6R1	SLC4A4	Q9UEW8	STK39	T254	I261N	261	Missense	distal	7	no	139.254	139.256	EPSD	ICGC;COSMIC	61.825	Up-regulation
STE_STE20_FRAY_STK39_ST	Q9Y6R1	SLC4A4	Q9UEW8	STK39	T254	S255F	255	Missense	proximal	1	no	139.254	153.236	EPSD	ICGC;COSMIC	61.825	Up-regulation
STE_STE20_FRAY_STK39_ST	Q9Y6R1	SLC4A4	Q9UEW8	STK39	S255	I261N	261	Missense	distal	6	no	70.159	70.144	EPSD	ICGC;COSMIC	61.825	Down-regulation
STE_STE20_FRAY_STK39_ST	Q9Y6R1	SLC4A4	Q9UEW8	STK39	S255	S255F	255	Missense	central	0	yes	70.159	0.000	EPSD	ICGC;COSMIC	61.825	Loss
STE_STE20_FRAY_STK39_ST	Q9Y6R1	SLC4A4	Q9UEW8	STK39	S396	I391T	391	Missense	distal	-5	no	39.542	63.958	EPSD	ICGC	61.825	Gain
STE_STE20_FRAY_STK39_ST	P55011	SLC12A2	Q9UEW8	STK39	T203	H204N	204	Missense	proximal	1	no	187.879	173.606	EPSD;PhosphoSitePlus	ICGC;COSMIC	61.825	Down-regulation
STE_STE20_FRAY_STK39_ST	P55011	SLC12A2	Q9UEW8	STK39	T207	H204N	204	Missense	distal	-3	no	156.614	152.829	PhosphoSitePlus;EPSD	ICGC;COSMIC	61.825	Down-regulation
STE_STE20_FRAY_STK39_ST	P55011	SLC12A2	Q9UEW8	STK39	T266	P267Q	267	Missense	proximal	1	no	65.275	53.083	EPSD	ICGC;COSMIC	61.825	Loss
STE_STE20_FRAY_STK39_ST	P55011	SLC12A2	Q9UEW8	STK39	S944	L938S	938	Missense	distal	-6	no	72.744	77.615	EPSD	ICGC;COSMIC;GDSC;CCLE	61.825	Up-regulation
STE_STE20_FRAY_STK39_ST	P55011	SLC12A2	Q9UEW8	STK39	S944	P945H	945	Missense	proximal	1	no	72.744	67.796	EPSD	ICGC;COSMIC	61.825	Down-regulation
STE_STE20_FRAY_STK39_ST	P55011	SLC12A2	Q9UEW8	STK39	T947	P945H	945	Missense	proximal	-2	no	81.260	86.112	EPSD	ICGC;COSMIC	61.825	Up-regulation
STE_STE20_FRAY_STK39_ST	P55011	SLC12A2	Q9UEW8	STK39	S953	K959N	959	Missense	distal	6	no	61.947	60.093	EPSD	ICGC	61.825	Loss
STE_STE20_FRAY_STK39_ST	P55011	SLC12A2	Q9UEW8	STK39	T964	K959N	959	Missense	distal	-5	no	84.888	86.087	EPSD	ICGC	61.825	Up-regulation
STE_STE20_FRAY_STK39_ST	P55011	SLC12A2	Q9UEW8	STK39	T964	D963Y	963	Missense	proximal	-1	no	84.888	85.739	EPSD	ICGC	61.825	Up-regulation
STE_STE20_FRAY_STK39_ST	P55011	SLC12A2	Q9UEW8	STK39	T964	P967Q	967	Missense	distal	3	no	84.888	84.185	EPSD	ICGC;COSMIC	61.825	Down-regulation
STE_STE20_FRAY_STK39_ST	P55011	SLC12A2	Q9UEW8	STK39	T986	Q987K	987	Missense	proximal	1	no	101.283	107.561	EPSD	ICGC;COSMIC	61.825	Up-regulation
STE_STE20_FRAY_STK39_ST	Q9H2X9	SLC12A5	Q9UEW8	STK39	T6	V7F	7	Missense	proximal	1	no	93.599	99.099	PhosphoSitePlus;EPSD	ICGC	61.825	Up-regulation
STE_STE20_FRAY_STK39_ST	Q9H2X9	SLC12A5	Q9UEW8	STK39	T6	S2N	2	Missense	distal	-4	no	93.599	86.888	PhosphoSitePlus;EPSD	ICGC;COSMIC;CCLE	61.825	Down-regulation
STE_STE20_FRAY_STK39_ST	Q9H2X9	SLC12A5	Q9UEW8	STK39	S49	N44T	44	Missense	distal	-5	no	47.043	62.122	EPSD	ICGC;COSMIC	61.825	Gain
STE_STE20_FRAY_STK39_ST	Q9H2X9	SLC12A5	Q9UEW8	STK39	S54	K61T	61	Missense	distal	7	no	63.461	63.458	EPSD	ICGC;COSMIC	61.825	Down-regulation
STE_STE20_FRAY_STK39_ST	Q9H2X9	SLC12A5	Q9UEW8	STK39	S54	S48I	48	Missense	distal	-6	no	63.461	53.313	EPSD	ICGC	61.825	Loss
STE_STE20_FRAY_STK39_ST	Q9H2X9	SLC12A5	Q9UEW8	STK39	S54	G60R	60	Missense	distal	6	no	63.461	64.799	EPSD	ICGC	61.825	Up-regulation
STE_STE20_FRAY_STK39_ST	Q9H2X9	SLC12A5	Q9UEW8	STK39	S54	I52L	52	Missense	proximal	-2	no	63.461	55.237	EPSD	ICGC;COSMIC	61.825	Loss
STE_STE20_FRAY_STK39_ST	Q9H2X9	SLC12A5	Q9UEW8	STK39	S54	G60E	60	Missense	distal	6	no	63.461	63.507	EPSD	ICGC;COSMIC	61.825	Up-regulation
STE_STE20_FRAY_STK39_ST	Q9H2X9	SLC12A5	Q9UEW8	STK39	T945	R949Q	949	Missense	distal	4	no	101.725	96.032	EPSD	ICGC;COSMIC	61.825	Down-regulation
STE_STE20_FRAY_STK39_ST	Q9H2X9	SLC12A5	Q9UEW8	STK39	T945	M942I	942	Missense	distal	-3	no	101.725	100.474	EPSD	ICGC	61.825	Down-regulation
STE_STE20_FRAY_STK39_ST	Q9H2X9	SLC12A5	Q9UEW8	STK39	T1030	P1024S	1024	Missense	distal	-6	no	116.173	117.311	EPSD	ICGC;COSMIC	61.825	Up-regulation
STE_STE20_FRAY_STK39_ST	Q9H2X9	SLC12A5	Q9UEW8	STK39	T1030	K1026N	1026	Missense	distal	-4	no	116.173	105.507	EPSD	ICGC	61.825	Down-regulation
STE_STE20_FRAY_STK39_ST	Q9H2X9	SLC12A5	Q9UEW8	STK39	T1032	K1026N	1026	Missense	distal	-6	no	134.520	137.706	EPSD;PhosphoSitePlus	ICGC	61.825	Up-regulation
STE_STE20_FRAY_STK39_ST	Q9H2X9	SLC12A5	Q9UEW8	STK39	S1045	E1050D	1050	Missense	distal	5	no	75.757	90.006	EPSD	ICGC	61.825	Up-regulation
STE_STE20_FRAY_STK39_ST	Q9H2X9	SLC12A5	Q9UEW8	STK39	S1045	G1043D	1043	Missense	proximal	-2	no	75.757	87.556	EPSD	ICGC;COSMIC	61.825	Up-regulation
STE_STE20_FRAY_STK39_ST	Q9H2X9	SLC12A5	Q9UEW8	STK39	S1048	G1043D	1043	Missense	distal	-5	no	37.491	71.728	EPSD	ICGC;COSMIC	61.825	Gain
STE_STE20_FRAY_STK39_ST	Q9Y666	SLC12A7	Q9UEW8	STK39	S960	A966V	966	Missense	distal	6	no	72.283	72.972	EPSD	ICGC;COSMIC	61.825	Up-regulation
STE_STE20_FRAY_STK39_ST	Q9Y666	SLC12A7	Q9UEW8	STK39	T962	A966V	966	Missense	distal	4	no	71.316	78.656	EPSD	ICGC;COSMIC	61.825	Up-regulation
STE_STE20_FRAY_STK39_ST	Q9Y666	SLC12A7	Q9UEW8	STK39	T973	A966V	966	Missense	distal	-7	no	142.688	142.797	PhosphoSitePlus;EPSD	ICGC;COSMIC	61.825	Up-regulation
STE_STE20_FRAY_STK39_ST	Q9Y666	SLC12A7	Q9UEW8	STK39	T973	T973K	973	Missense	central	0	yes	142.688	0.000	PhosphoSitePlus;EPSD	ICGC	61.825	Loss
STE_STE20_FRAY_STK39_ST	Q9Y666	SLC12A7	Q9UEW8	STK39	T980	T973K	973	Missense	distal	-7	no	144.176	143.596	EPSD;PhosphoSitePlus	ICGC	61.825	Down-regulation
STE_STE20_FRAY_STK39_ST	Q9Y666	SLC12A7	Q9UEW8	STK39	T980	T982N	982	Missense	proximal	2	no	144.176	137.307	EPSD;PhosphoSitePlus	ICGC	61.825	Down-regulation
STE_STE20_FRAY_STK39_ST	Q9Y666	SLC12A7	Q9UEW8	STK39	T982	T982N	982	Missense	central	0	yes	67.085	0.000	EPSD	ICGC	61.825	Loss
STE_STE20_FRAY_STK39_ST	Q9UHW9	SLC12A6	Q9UEW8	STK39	T18	P19H	19	Missense	proximal	1	no	108.850	103.902	EPSD	ICGC;COSMIC	61.825	Down-regulation
STE_STE20_FRAY_STK39_ST	Q9UHW9	SLC12A6	Q9UEW8	STK39	T18	P19L	19	Missense	proximal	1	no	108.850	83.358	EPSD	ICGC;COSMIC	61.825	Down-regulation
STE_STE20_FRAY_STK39_ST	Q9UHW9	SLC12A6	Q9UEW8	STK39	T20	P19H	19	Missense	proximal	-1	no	92.495	95.302	EPSD	ICGC;COSMIC	61.825	Up-regulation
STE_STE20_FRAY_STK39_ST	Q9UHW9	SLC12A6	Q9UEW8	STK39	T20	P19L	19	Missense	proximal	-1	no	92.495	90.518	EPSD	ICGC;COSMIC	61.825	Down-regulation
STE_STE20_FRAY_STK39_ST	Q9UHW9	SLC12A6	Q9UEW8	STK39	S29	D30E	30	Missense	proximal	1	no	73.880	61.014	EPSD	ICGC	61.825	Loss
STE_STE20_FRAY_STK39_ST	Q9UHW9	SLC12A6	Q9UEW8	STK39	S29	S36L	36	Missense	distal	7	no	73.880	73.847	EPSD	ICGC;COSMIC	61.825	Down-regulation
STE_STE20_FRAY_STK39_ST	Q9UHW9	SLC12A6	Q9UEW8	STK39	T54	S50R	50	Missense	distal	-4	no	71.164	65.823	EPSD	ICGC	61.825	Down-regulation
STE_STE20_FRAY_STK39_ST	Q9UHW9	SLC12A6	Q9UEW8	STK39	T54	T54K	54	Missense	central	0	yes	71.164	0.000	EPSD	ICGC;COSMIC	61.825	Loss
STE_STE20_FRAY_STK39_ST	Q9UHW9	SLC12A6	Q9UEW8	STK39	T54	S55R	55	Missense	proximal	1	no	71.164	72.045	EPSD	ICGC	61.825	Up-regulation
STE_STE20_FRAY_STK39_ST	Q9UHW9	SLC12A6	Q9UEW8	STK39	S96	T98N	98	Missense	proximal	2	no	125.264	118.395	EPSD;PhosphoSitePlus	ICGC	61.825	Down-regulation
STE_STE20_FRAY_STK39_ST	Q9UHW9	SLC12A6	Q9UEW8	STK39	T157	L159F	159	Missense	proximal	2	no	55.144	65.636	EPSD	ICGC;COSMIC	61.825	Gain
STE_STE20_FRAY_STK39_ST	Q9UHW9	SLC12A6	Q9UEW8	STK39	T157	L159I	159	Missense	proximal	2	no	55.144	72.073	EPSD	ICGC;COSMIC	61.825	Gain
STE_STE20_FRAY_STK39_ST	Q9UHW9	SLC12A6	Q9UEW8	STK39	T160	A163E	163	Missense	distal	3	no	133.263	133.236	EPSD;PhosphoSitePlus	ICGC	61.825	Down-regulation
STE_STE20_FRAY_STK39_ST	Q9UHW9	SLC12A6	Q9UEW8	STK39	T160	L159F	159	Missense	proximal	-1	no	133.263	135.749	EPSD;PhosphoSitePlus	ICGC;COSMIC	61.825	Up-regulation
STE_STE20_FRAY_STK39_ST	Q9UHW9	SLC12A6	Q9UEW8	STK39	T160	L159I	159	Missense	proximal	-1	no	133.263	131.610	EPSD;PhosphoSitePlus	ICGC;COSMIC	61.825	Down-regulation
STE_STE20_FRAY_STK39_ST	Q9UP95	SLC12A4	Q9UEW8	STK39	T93	V87A	87	Missense	distal	-6	no	102.478	111.619	EPSD	ICGC;COSMIC	61.825	Up-regulation
STE_STE20_FRAY_STK39_ST	Q9UP95	SLC12A4	Q9UEW8	STK39	T983	G976E	976	Missense	distal	-7	no	176.865	176.862	PhosphoSitePlus;EPSD	ICGC;COSMIC	61.825	Down-regulation
STE_STE20_FRAY_STK39_ST	Q9UP95	SLC12A4	Q9UEW8	STK39	T983	T983M	983	Missense	central	0	yes	176.865	0.000	PhosphoSitePlus;EPSD	ICGC;COSMIC	61.825	Loss
STE_STE20_FRAY_STK39_ST	Q9UP95	SLC12A4	Q9UEW8	STK39	T985	T983M	983	Missense	proximal	-2	no	90.002	89.753	EPSD	ICGC;COSMIC	61.825	Down-regulation
STE_STE20_FRAY_STK39_ST	Q9UP95	SLC12A4	Q9UEW8	STK39	T991	P996H	996	Missense	distal	5	no	98.365	106.910	EPSD	ICGC;COSMIC	61.825	Up-regulation
STE_STE20_FRAY_STK39_ST	Q9UP95	SLC12A4	Q9UEW8	STK39	T991	D995N	995	Missense	distal	4	no	98.365	95.266	EPSD	ICGC;COSMIC	61.825	Down-regulation
STE_STE20_FRAY_STK39_ST	Q9UP95	SLC12A4	Q9UEW8	STK39	T993	P996H	996	Missense	distal	3	no	106.793	107.151	EPSD	ICGC;COSMIC	61.825	Up-regulation
STE_STE20_FRAY_STK39_ST	Q9UP95	SLC12A4	Q9UEW8	STK39	T993	D995N	995	Missense	proximal	2	no	106.793	95.835	EPSD	ICGC;COSMIC	61.825	Down-regulation
STE_STE20_FRAY_STK39_ST	P55017	SLC12A3	Q9UEW8	STK39	T14	A13T	13	Missense	proximal	-1	no	75.566	78.457	EPSD	ICGC;COSMIC;GDSC;CCLE	61.825	Up-regulation
STE_STE20_FRAY_STK39_ST	P55017	SLC12A3	Q9UEW8	STK39	T55	I61T	61	Missense	distal	6	no	164.354	163.859	EPSD;PhosphoSitePlus	ICGC	61.825	Down-regulation
STE_STE20_FRAY_STK39_ST	P55017	SLC12A3	Q9UEW8	STK39	T60	I61T	61	Missense	proximal	1	no	159.444	151.799	PhosphoSitePlus;EPSD	ICGC	61.825	Down-regulation
STE_STE20_FRAY_STK39_ST	P55017	SLC12A3	Q9UEW8	STK39	T66	I61T	61	Missense	distal	-5	no	69.898	94.313	EPSD	ICGC	61.825	Up-regulation
STE_STE20_FRAY_STK39_ST	P55017	SLC12A3	Q9UEW8	STK39	T85	V82F	82	Missense	distal	-3	no	60.708	61.905	EPSD	ICGC	61.825	Gain
TKL_IRAK_IRAK1_ST	Q96FA3	PELI1	P51617	IRAK1	S70	S70C	70	Missense	central	0	yes	121.890	0.000	EPSD;PhosphoSitePlus	ICGC	67.712	Loss
TKL_IRAK_IRAK1_ST	Q96FA3	PELI1	P51617	IRAK1	S70	A65D	65	Missense	distal	-5	no	121.890	127.708	EPSD;PhosphoSitePlus	ICGC	67.712	Up-regulation
TKL_IRAK_IRAK1_ST	Q96FA3	PELI1	P51617	IRAK1	S70	Q74K	74	Missense	distal	4	no	121.890	119.260	EPSD;PhosphoSitePlus	ICGC;COSMIC	67.712	Down-regulation
TKL_IRAK_IRAK1_ST	Q96FA3	PELI1	P51617	IRAK1	S70	A66E	66	Missense	distal	-4	no	121.890	114.140	EPSD;PhosphoSitePlus	ICGC;COSMIC	67.712	Down-regulation
TKL_IRAK_IRAK1_ST	Q96FA3	PELI1	P51617	IRAK1	S70	N71K	71	Missense	proximal	1	no	121.890	121.640	EPSD;PhosphoSitePlus	ICGC	67.712	Down-regulation
TKL_IRAK_IRAK1_ST	Q96FA3	PELI1	P51617	IRAK1	S70	Q64K	64	Missense	distal	-6	no	121.890	110.476	EPSD;PhosphoSitePlus	ICGC;COSMIC	67.712	Down-regulation
TKL_IRAK_IRAK1_ST	Q96FA3	PELI1	P51617	IRAK1	S70	A66T	66	Missense	distal	-4	no	121.890	114.074	EPSD;PhosphoSitePlus	ICGC;COSMIC	67.712	Down-regulation
TKL_IRAK_IRAK1_ST	Q96FA3	PELI1	P51617	IRAK1	S70	H75Y	75	Missense	distal	5	no	121.890	122.783	EPSD;PhosphoSitePlus	ICGC;COSMIC	67.712	Up-regulation
TKL_IRAK_IRAK1_ST	Q96FA3	PELI1	P51617	IRAK1	S76	S70C	70	Missense	distal	-6	no	121.388	124.908	EPSD;PhosphoSitePlus	ICGC	67.712	Up-regulation
TKL_IRAK_IRAK1_ST	Q96FA3	PELI1	P51617	IRAK1	S76	R83Q	83	Missense	distal	7	no	121.388	121.106	EPSD;PhosphoSitePlus	ICGC;COSMIC	67.712	Down-regulation
TKL_IRAK_IRAK1_ST	Q96FA3	PELI1	P51617	IRAK1	S76	Q74K	74	Missense	proximal	-2	no	121.388	120.830	EPSD;PhosphoSitePlus	ICGC;COSMIC	67.712	Down-regulation
TKL_IRAK_IRAK1_ST	Q96FA3	PELI1	P51617	IRAK1	S76	N71K	71	Missense	distal	-5	no	121.388	121.095	EPSD;PhosphoSitePlus	ICGC	67.712	Down-regulation
TKL_IRAK_IRAK1_ST	Q96FA3	PELI1	P51617	IRAK1	S76	H75Y	75	Missense	proximal	-1	no	121.388	122.253	EPSD;PhosphoSitePlus	ICGC;COSMIC	67.712	Up-regulation
TKL_IRAK_IRAK1_ST	Q96FA3	PELI1	P51617	IRAK1	S78	R83Q	83	Missense	distal	5	no	133.451	132.415	EPSD;PhosphoSitePlus	ICGC;COSMIC	67.712	Down-regulation
TKL_IRAK_IRAK1_ST	Q96FA3	PELI1	P51617	IRAK1	S78	Q74K	74	Missense	distal	-4	no	133.451	130.185	EPSD;PhosphoSitePlus	ICGC;COSMIC	67.712	Down-regulation
TKL_IRAK_IRAK1_ST	Q96FA3	PELI1	P51617	IRAK1	S78	N71K	71	Missense	distal	-7	no	133.451	133.326	EPSD;PhosphoSitePlus	ICGC	67.712	Down-regulation
TKL_IRAK_IRAK1_ST	Q96FA3	PELI1	P51617	IRAK1	S78	H75Y	75	Missense	distal	-3	no	133.451	133.683	EPSD;PhosphoSitePlus	ICGC;COSMIC	67.712	Up-regulation
TKL_IRAK_IRAK1_ST	Q96FA3	PELI1	P51617	IRAK1	T80	R83Q	83	Missense	distal	3	no	113.437	112.925	PhosphoSitePlus;EPSD	ICGC;COSMIC	67.712	Down-regulation
TKL_IRAK_IRAK1_ST	Q96FA3	PELI1	P51617	IRAK1	T80	Q74K	74	Missense	distal	-6	no	113.437	102.023	PhosphoSitePlus;EPSD	ICGC;COSMIC	67.712	Down-regulation
TKL_IRAK_IRAK1_ST	Q96FA3	PELI1	P51617	IRAK1	T80	H75Y	75	Missense	distal	-5	no	113.437	111.280	PhosphoSitePlus;EPSD	ICGC;COSMIC	67.712	Down-regulation
TKL_IRAK_IRAK1_ST	Q96FA3	PELI1	P51617	IRAK1	S82	R83Q	83	Missense	proximal	1	no	122.719	122.992	EPSD;PhosphoSitePlus	ICGC;COSMIC	67.712	Up-regulation
TKL_IRAK_IRAK1_ST	Q96FA3	PELI1	P51617	IRAK1	S82	H75Y	75	Missense	distal	-7	no	122.719	120.387	EPSD;PhosphoSitePlus	ICGC;COSMIC	67.712	Down-regulation
TKL_IRAK_IRAK1_ST	Q96FA3	PELI1	P51617	IRAK1	T86	R83Q	83	Missense	distal	-3	no	110.913	111.044	EPSD;PhosphoSitePlus	ICGC;COSMIC	67.712	Up-regulation
TKL_IRAK_IRAK1_ST	Q96FA3	PELI1	P51617	IRAK1	S125	T127A	127	Missense	proximal	2	no	117.669	126.965	EPSD;PhosphoSitePlus	ICGC;COSMIC	67.712	Up-regulation
TKL_IRAK_IRAK1_ST	Q96FA3	PELI1	P51617	IRAK1	T127	T127A	127	Missense	central	0	yes	125.413	0.000	EPSD;PhosphoSitePlus	ICGC;COSMIC	67.712	Loss
TKL_IRAK_IRAK1_ST	Q96FA3	PELI1	P51617	IRAK1	T288	N287D	287	Missense	proximal	-1	no	130.428	129.117	EPSD;PhosphoSitePlus	ICGC;COSMIC	67.712	Down-regulation
TKL_IRAK_IRAK1_ST	Q96FA3	PELI1	P51617	IRAK1	S293	N287D	287	Missense	distal	-6	no	116.243	116.206	EPSD;PhosphoSitePlus	ICGC;COSMIC	67.712	Down-regulation
TKL_IRAK_IRAK1_ST	P51617	IRAK1	P51617	IRAK1	T381	G386C	386	Missense	distal	5	no	80.256	80.061	EPSD	ICGC	67.712	Down-regulation
TKL_IRAK_IRAK1_ST	P51617	IRAK1	P51617	IRAK1	T387	G386C	386	Missense	proximal	-1	no	112.578	107.889	PhosphoSitePlus;EPSD	ICGC	67.712	Down-regulation
TKL_IRAK_IRAK1_ST	Q9HAT8	PELI2	P51617	IRAK1	S78	R85M	85	Missense	distal	7	no	72.191	71.027	EPSD	ICGC;COSMIC	67.712	Down-regulation
TKL_IRAK_IRAK1_ST	Q9HAT8	PELI2	P51617	IRAK1	S80	R85M	85	Missense	distal	5	no	91.169	91.168	EPSD	ICGC;COSMIC	67.712	Down-regulation
TKL_IRAK_IRAK1_ST	Q9HAT8	PELI2	P51617	IRAK1	T82	R85M	85	Missense	distal	3	no	113.740	110.618	EPSD	ICGC;COSMIC	67.712	Down-regulation
TKL_IRAK_IRAK1_ST	Q9HAT8	PELI2	P51617	IRAK1	S84	R85M	85	Missense	proximal	1	no	75.820	76.932	EPSD	ICGC;COSMIC	67.712	Up-regulation
TKL_IRAK_IRAK1_ST	Q9HAT8	PELI2	P51617	IRAK1	T88	R85M	85	Missense	distal	-3	no	85.663	85.908	EPSD	ICGC;COSMIC	67.712	Up-regulation
TKL_IRAK_IRAK1_ST	Q9HAT8	PELI2	P51617	IRAK1	S235	G230V	230	Missense	distal	-5	no	78.469	71.613	EPSD	ICGC	67.712	Down-regulation
TKL_IRAK_IRAK1_ST	Q9HAT8	PELI2	P51617	IRAK1	T237	G243V	243	Missense	distal	6	no	68.495	85.678	EPSD	ICGC	67.712	Up-regulation
TKL_IRAK_IRAK1_ST	Q9HAT8	PELI2	P51617	IRAK1	T237	G230V	230	Missense	distal	-7	no	68.495	64.146	EPSD	ICGC	67.712	Loss
TKL_IRAK_IRAK1_ST	Q9HAT8	PELI2	P51617	IRAK1	T290	T290I	290	Missense	central	0	yes	135.720	0.000	PhosphoSitePlus	ICGC;COSMIC	67.712	Loss
TKL_IRAK_IRAK1_ST	Q9HAT8	PELI2	P51617	IRAK1	S295	T290I	290	Missense	distal	-5	no	95.219	97.105	EPSD	ICGC;COSMIC	67.712	Up-regulation
TKL_IRAK_IRAK1_ST	P40763	STAT3	P51617	IRAK1	T545	N538K	538	Missense	distal	-7	no	71.747	71.623	EPSD	ICGC;COSMIC	67.712	Down-regulation
TKL_IRAK_IRAK1_ST	P40763	STAT3	P51617	IRAK1	T545	G541W	541	Missense	distal	-4	no	71.747	76.278	EPSD	ICGC;COSMIC	67.712	Up-regulation
TKL_IRAK_IRAK1_ST	P40763	STAT3	P51617	IRAK1	T632	P639Q	639	Missense	distal	7	no	75.720	78.875	EPSD	ICGC	67.712	Up-regulation
TKL_IRAK_IRAK1_ST	P40763	STAT3	P51617	IRAK1	T632	S629N	629	Missense	distal	-3	no	75.720	76.123	EPSD	ICGC	67.712	Up-regulation
TKL_IRAK_IRAK1_ST	P40763	STAT3	P51617	IRAK1	S727	L724P	724	Missense	distal	-3	no	112.460	112.292	PhosphoSitePlus	ICGC;COSMIC	67.712	Down-regulation
TKL_IRAK_IRAK1_ST	P40763	STAT3	P51617	IRAK1	S727	S727P	727	Missense	central	0	yes	112.460	0.000	PhosphoSitePlus	ICGC	67.712	Loss
TKL_IRAK_IRAK1_ST	P40763	STAT3	P51617	IRAK1	S727	L734S	734	Missense	distal	7	no	112.460	115.702	PhosphoSitePlus	ICGC;COSMIC	67.712	Up-regulation
CMGC_CDKL_CDKL5_ST	Q9HCJ2	LRRC4C	O76039	CDKL5	S173	R176Q	176	Missense	distal	3	no	4.176	4.260	EPSD	ICGC	2.968	Up-regulation
CMGC_CDKL_CDKL5_ST	Q9HCJ2	LRRC4C	O76039	CDKL5	S173	R176L	176	Missense	distal	3	no	4.176	4.184	EPSD	ICGC;COSMIC	2.968	Up-regulation
CMGC_CDKL_CDKL5_ST	Q9HCJ2	LRRC4C	O76039	CDKL5	S383	P389A	389	Missense	distal	6	no	2.790	3.181	EPSD	ICGC;COSMIC	2.968	Gain
CMGC_CDKL_CDKL5_ST	Q9HCJ2	LRRC4C	O76039	CDKL5	S631	Q636K	636	Missense	distal	5	no	6.210	6.205	PhosphoSitePlus	ICGC;COSMIC	2.968	Down-regulation
CMGC_CDKL_CDKL5_ST	Q9HCJ2	LRRC4C	O76039	CDKL5	S631	T638N	638	Missense	distal	7	no	6.210	6.250	PhosphoSitePlus	ICGC	2.968	Up-regulation
CMGC_CDKL_CDKL5_ST	O76039	CDKL5	O76039	CDKL5	T169	G163R	163	Missense	distal	-6	no	12.683	12.595	EPSD;PhosphoSitePlus	ICGC;COSMIC	2.968	Down-regulation
CMGC_CDKL_CDKL5_ST	O76039	CDKL5	O76039	CDKL5	T169	E170G	170	Missense	proximal	1	no	12.683	12.651	EPSD;PhosphoSitePlus	ICGC;COSMIC	2.968	Down-regulation
CMGC_CDKL_CDKL5_ST	O76039	CDKL5	O76039	CDKL5	S350	R355L	355	Missense	distal	5	no	4.962	4.963	EPSD	ICGC	2.968	Up-regulation
CMGC_CDKL_CDKL5_ST	O76039	CDKL5	O76039	CDKL5	T554	R547K	547	Missense	distal	-7	no	2.714	3.175	EPSD	ICGC	2.968	Gain
CMGC_CDKL_CDKL5_ST	O76039	CDKL5	O76039	CDKL5	T658	P655Q	655	Missense	distal	-3	no	2.677	3.013	EPSD	ICGC;COSMIC	2.968	Gain
CMGC_CDKL_CDKL5_ST	O76039	CDKL5	O76039	CDKL5	S766	W759L	759	Missense	distal	-7	no	4.173	3.127	EPSD	ICGC;COSMIC	2.968	Down-regulation
CMGC_CDKL_CDKL5_ST	O76039	CDKL5	O76039	CDKL5	S766	L771R	771	Missense	distal	5	no	4.173	4.172	EPSD	ICGC	2.968	Down-regulation
CMGC_CDKL_CDKL5_ST	O76039	CDKL5	O76039	CDKL5	S766	Q770K	770	Missense	distal	4	no	4.173	4.175	EPSD	ICGC;COSMIC	2.968	Up-regulation
CMGC_CDKL_CDKL5_ST	O76039	CDKL5	O76039	CDKL5	S766	E773K	773	Missense	distal	7	no	4.173	4.200	EPSD	ICGC;COSMIC	2.968	Up-regulation
CMGC_CDKL_CDKL5_ST	O76039	CDKL5	O76039	CDKL5	S766	L771H	771	Missense	distal	5	no	4.173	4.178	EPSD	ICGC;COSMIC	2.968	Up-regulation
CMGC_CDKL_CDKL5_ST	O76039	CDKL5	O76039	CDKL5	S768	L771R	771	Missense	distal	3	no	2.983	2.975	EPSD	ICGC	2.968	Down-regulation
CMGC_CDKL_CDKL5_ST	O76039	CDKL5	O76039	CDKL5	S768	Q770K	770	Missense	proximal	2	no	2.983	2.875	EPSD	ICGC;COSMIC	2.968	Loss
CMGC_CDKL_CDKL5_ST	O76039	CDKL5	O76039	CDKL5	S768	E773K	773	Missense	distal	5	no	2.983	2.982	EPSD	ICGC;COSMIC	2.968	Down-regulation
CMGC_CDKL_CDKL5_ST	O76039	CDKL5	O76039	CDKL5	S768	L771H	771	Missense	distal	3	no	2.983	2.943	EPSD	ICGC;COSMIC	2.968	Loss
CMGC_CDKL_CDKL5_ST	O76039	CDKL5	O76039	CDKL5	S796	Q791K	791	Missense	distal	-5	no	3.186	3.119	EPSD	ICGC;COSMIC	2.968	Down-regulation
CMGC_CDKL_CDKL5_ST	O76039	CDKL5	O76039	CDKL5	T803	H809Y	809	Missense	distal	6	no	2.974	2.944	EPSD	ICGC	2.968	Loss
CMGC_CDKL_CDKL5_ST	Q66K74	MAP1S	O76039	CDKL5	S766	S762N	762	Missense	distal	-4	no	5.382	5.364	EPSD	ICGC;COSMIC	2.968	Down-regulation
CMGC_CDKL_CDKL5_ST	Q8TDM6	DLG5	O76039	CDKL5	S711	V706M	706	Missense	distal	-5	no	3.698	3.652	EPSD	ICGC;COSMIC	2.968	Down-regulation
CMGC_CDKL_CDKL5_ST	Q8TDM6	DLG5	O76039	CDKL5	S711	V705A	705	Missense	distal	-6	no	3.698	3.751	EPSD	ICGC;COSMIC	2.968	Up-regulation
CMGC_CDKL_CDKL5_ST	Q8TDM6	DLG5	O76039	CDKL5	S779	R782H	782	Missense	distal	3	no	5.521	5.488	EPSD	ICGC;COSMIC	2.968	Down-regulation
CMGC_CDKL_CDKL5_ST	Q8TDM6	DLG5	O76039	CDKL5	S865	P861T	861	Missense	distal	-4	no	4.577	4.643	EPSD	ICGC;COSMIC	2.968	Up-regulation
CMGC_CDKL_CDKL5_ST	Q8TDM6	DLG5	O76039	CDKL5	S865	S864G	864	Missense	proximal	-1	no	4.577	4.636	EPSD	ICGC;COSMIC	2.968	Up-regulation
CMGC_CDKL_CDKL5_ST	Q8TDM6	DLG5	O76039	CDKL5	S897	R903H	903	Missense	distal	6	no	3.860	3.431	EPSD	ICGC;COSMIC	2.968	Down-regulation
CMGC_CDKL_CDKL5_ST	Q8TDM6	DLG5	O76039	CDKL5	S897	R896C	896	Missense	proximal	-1	no	3.860	3.881	EPSD	ICGC;COSMIC	2.968	Up-regulation
CMGC_CDKL_CDKL5_ST	Q8TDM6	DLG5	O76039	CDKL5	S900	R903H	903	Missense	distal	3	no	3.768	3.735	EPSD	ICGC;COSMIC	2.968	Down-regulation
CMGC_CDKL_CDKL5_ST	Q8TDM6	DLG5	O76039	CDKL5	S900	R896C	896	Missense	distal	-4	no	3.768	3.776	EPSD	ICGC;COSMIC	2.968	Up-regulation
CMGC_CDKL_CDKL5_ST	Q8TDM6	DLG5	O76039	CDKL5	S1019	P1016S	1016	Missense	distal	-3	no	3.783	4.164	EPSD	ICGC;GDSC;CCLE	2.968	Up-regulation
CMGC_CDKL_CDKL5_ST	Q8TDM6	DLG5	O76039	CDKL5	S1019	S1021Y	1021	Missense	proximal	2	no	3.783	3.975	EPSD	ICGC;COSMIC	2.968	Up-regulation
CMGC_CDKL_CDKL5_ST	Q8TDM6	DLG5	O76039	CDKL5	S1019	R1018M	1018	Missense	proximal	-1	no	3.783	3.825	EPSD	ICGC;COSMIC	2.968	Up-regulation
CMGC_CDKL_CDKL5_ST	Q8TDM6	DLG5	O76039	CDKL5	S1118	R1112Q	1112	Missense	distal	-6	no	4.571	4.639	EPSD	ICGC;COSMIC	2.968	Up-regulation
CMGC_CDKL_CDKL5_ST	Q8TDM6	DLG5	O76039	CDKL5	S1278	R1273H	1273	Missense	distal	-5	no	4.516	3.998	EPSD	ICGC;COSMIC	2.968	Down-regulation
CMGC_CDKL_CDKL5_ST	Q8TDM6	DLG5	O76039	CDKL5	S1278	P1283S	1283	Missense	distal	5	no	4.516	4.508	EPSD	ICGC;COSMIC;GDSC;CCLE	2.968	Down-regulation
CMGC_CDKL_CDKL5_ST	Q8TDM6	DLG5	O76039	CDKL5	T1677	A1676T	1676	Missense	proximal	-1	no	3.207	3.282	EPSD	ICGC;COSMIC	2.968	Up-regulation
CMGC_CDKL_CDKL5_ST	Q8TDM6	DLG5	O76039	CDKL5	T1677	S1675I	1675	Missense	proximal	-2	no	3.207	3.759	EPSD	ICGC;COSMIC	2.968	Up-regulation
CMGC_CDKL_CDKL5_ST	Q8TDM6	DLG5	O76039	CDKL5	S1700	R1697C	1697	Missense	distal	-3	no	4.675	4.134	EPSD	ICGC;COSMIC	2.968	Down-regulation
CMGC_CDKL_CDKL5_ST	Q8TDM6	DLG5	O76039	CDKL5	S1700	S1700P	1700	Missense	central	0	yes	4.675	0.000	EPSD	ICGC	2.968	Loss
CMGC_MAPK_p38_MAPK11_ST	P15336	ATF2	Q15759	MAPK11	S136	E130K	130	Missense	distal	-6	no	36.910	36.950	EPSD	ICGC;COSMIC	33.886	Up-regulation
CMGC_MAPK_p38_MAPK11_ST	P15336	ATF2	Q15759	MAPK11	S314	S321G	321	Missense	distal	7	no	35.026	34.395	EPSD	ICGC;COSMIC	33.886	Down-regulation
CMGC_MAPK_p38_MAPK11_ST	P15336	ATF2	Q15759	MAPK11	T325	S321G	321	Missense	distal	-4	no	40.490	38.486	EPSD	ICGC;COSMIC	33.886	Down-regulation
CMGC_MAPK_p38_MAPK11_ST	P15336	ATF2	Q15759	MAPK11	S328	S321G	321	Missense	distal	-7	no	36.572	36.429	EPSD	ICGC;COSMIC	33.886	Down-regulation
CMGC_MAPK_p38_MAPK11_ST	P15336	ATF2	Q15759	MAPK11	T333	S340L	340	Missense	distal	7	no	42.604	41.782	EPSD	ICGC;COSMIC	33.886	Down-regulation
CMGC_MAPK_p38_MAPK11_ST	P15336	ATF2	Q15759	MAPK11	T333	Q337H	337	Missense	distal	4	no	42.604	41.756	EPSD	ICGC;COSMIC	33.886	Down-regulation
CMGC_MAPK_p38_MAPK11_ST	P04179	SOD2	Q15759	MAPK11	T79	G76S	76	Missense	distal	-3	no	45.525	45.721	PhosphoSitePlus;EPSD	ICGC	33.886	Up-regulation
CMGC_MAPK_p38_MAPK11_ST	P04179	SOD2	Q15759	MAPK11	T79	G76V	76	Missense	distal	-3	no	45.525	46.768	PhosphoSitePlus;EPSD	ICGC;COSMIC	33.886	Up-regulation
CMGC_MAPK_p38_MAPK11_ST	P04179	SOD2	Q15759	MAPK11	S106	G109D	109	Missense	distal	3	no	47.202	47.176	EPSD;PhosphoSitePlus	ICGC;COSMIC	33.886	Down-regulation
CMGC_MAPK_p38_MAPK11_ST	Q15759	MAPK11	Q15759	MAPK11	S61	P58S	58	Missense	distal	-3	no	35.667	35.525	EPSD	ICGC;COSMIC	33.886	Down-regulation
CMGC_MAPK_p38_MAPK11_ST	Q15759	MAPK11	Q15759	MAPK11	S61	R57C	57	Missense	distal	-4	no	35.667	32.824	EPSD	ICGC;COSMIC	33.886	Loss
CMGC_MAPK_p38_MAPK11_ST	Q15759	MAPK11	Q15759	MAPK11	S61	A65V	65	Missense	distal	4	no	35.667	33.653	EPSD	ICGC;COSMIC	33.886	Loss
CMGC_MAPK_p38_MAPK11_ST	Q15759	MAPK11	Q15759	MAPK11	S61	P58H	58	Missense	distal	-3	no	35.667	36.249	EPSD	ICGC;COSMIC	33.886	Up-regulation
CMGC_MAPK_p38_MAPK11_ST	Q15759	MAPK11	Q15759	MAPK11	T241	M236L	236	Missense	distal	-5	no	46.807	46.687	PhosphoSitePlus;EPSD	ICGC;COSMIC	33.886	Down-regulation
CMGC_MAPK_p38_MAPK11_ST	Q15759	MAPK11	Q15759	MAPK11	T241	S243R	243	Missense	proximal	2	no	46.807	46.062	PhosphoSitePlus;EPSD	ICGC	33.886	Down-regulation
CMGC_MAPK_p38_MAPK11_ST	Q15759	MAPK11	Q15759	MAPK11	S243	M236L	236	Missense	distal	-7	no	35.783	35.716	EPSD	ICGC;COSMIC	33.886	Down-regulation
CMGC_MAPK_p38_MAPK11_ST	Q15759	MAPK11	Q15759	MAPK11	S243	S243R	243	Missense	central	0	yes	35.783	0.000	EPSD	ICGC	33.886	Loss
CMGC_MAPK_p38_MAPK11_ST	Q15759	MAPK11	Q15759	MAPK11	S261	R256L	256	Missense	distal	-5	no	43.429	43.342	EPSD;PhosphoSitePlus	ICGC;COSMIC	33.886	Down-regulation
CMGC_MAPK_p38_MAPK11_ST	O00418	EEF2K	Q15759	MAPK11	S74	P75A	75	Missense	proximal	1	no	41.457	32.421	EPSD	ICGC;COSMIC	33.886	Loss
CMGC_MAPK_p38_MAPK11_ST	O00418	EEF2K	Q15759	MAPK11	S74	P75L	75	Missense	proximal	1	no	41.457	31.639	EPSD	ICGC;COSMIC	33.886	Loss
CMGC_MAPK_p38_MAPK11_ST	O00418	EEF2K	Q15759	MAPK11	S74	S71F	71	Missense	distal	-3	no	41.457	42.277	EPSD	ICGC;COSMIC	33.886	Up-regulation
CMGC_MAPK_p38_MAPK11_ST	O00418	EEF2K	Q15759	MAPK11	S74	F79L	79	Missense	distal	5	no	41.457	40.925	EPSD	ICGC	33.886	Down-regulation
CMGC_MAPK_p38_MAPK11_ST	O00418	EEF2K	Q15759	MAPK11	S78	F79L	79	Missense	proximal	1	no	-0.708	36.906	EPSD	ICGC	33.886	Gain
CMGC_MAPK_p38_MAPK11_ST	O00418	EEF2K	Q15759	MAPK11	S359	Q361R	361	Missense	proximal	2	no	45.186	45.697	EPSD	ICGC	33.886	Up-regulation
CMGC_MAPK_p38_MAPK11_ST	O00418	EEF2K	Q15759	MAPK11	S359	P360L	360	Missense	proximal	1	no	45.186	35.369	EPSD	ICGC	33.886	Down-regulation
CMGC_MAPK_p38_MAPK11_ST	O00418	EEF2K	Q15759	MAPK11	T401	S404C	404	Missense	distal	3	no	39.858	37.803	EPSD	ICGC	33.886	Down-regulation
CMGC_MAPK_p38_MAPK11_ST	Q00613	HSF1	Q15759	MAPK11	S230	P223L	223	Missense	distal	-7	no	39.225	39.139	EPSD	ICGC	33.886	Down-regulation
CMGC_MAPK_p38_MAPK11_ST	Q00613	HSF1	Q15759	MAPK11	S241	P239L	239	Missense	proximal	-2	no	37.122	36.786	EPSD	ICGC;CCLE	33.886	Down-regulation
CMGC_MAPK_p38_MAPK11_ST	Q00613	HSF1	Q15759	MAPK11	S275	A278T	278	Missense	distal	3	no	42.662	43.421	EPSD	ICGC	33.886	Up-regulation
CMGC_MAPK_p38_MAPK11_ST	Q00613	HSF1	Q15759	MAPK11	S279	A278T	278	Missense	proximal	-1	no	40.834	41.153	EPSD	ICGC	33.886	Up-regulation
CMGC_MAPK_p38_MAPK11_ST	Q00613	HSF1	Q15759	MAPK11	S419	S421L	421	Missense	proximal	2	no	42.318	41.393	EPSD	ICGC;COSMIC	33.886	Down-regulation
CMGC_MAPK_p38_MAPK11_ST	Q00613	HSF1	Q15759	MAPK11	S419	S419G	419	Missense	central	0	yes	42.318	0.000	EPSD	ICGC;COSMIC	33.886	Loss
CMGC_MAPK_p38_MAPK11_ST	Q00613	HSF1	Q15759	MAPK11	S444	A437S	437	Missense	distal	-7	no	41.001	41.167	EPSD	ICGC;COSMIC	33.886	Up-regulation
CMGC_MAPK_p38_MAPK11_ST	Q8N122	RPTOR	Q15759	MAPK11	S696	T699M	699	Missense	distal	3	no	35.586	34.991	EPSD	ICGC;COSMIC	33.886	Down-regulation
CMGC_MAPK_p38_MAPK11_ST	Q8N122	RPTOR	Q15759	MAPK11	S704	T699M	699	Missense	distal	-5	no	33.943	33.844	EPSD	ICGC;COSMIC	33.886	Loss
CMGC_MAPK_p38_MAPK11_ST	Q8N122	RPTOR	Q15759	MAPK11	T706	T699M	699	Missense	distal	-7	no	35.602	35.466	EPSD	ICGC;COSMIC	33.886	Down-regulation
CMGC_MAPK_p38_MAPK11_ST	Q8N122	RPTOR	Q15759	MAPK11	S887	S887N	887	Missense	central	0	yes	42.638	0.000	EPSD	ICGC;COSMIC	33.886	Loss
CMGC_MAPK_p38_MAPK11_ST	Q8N122	RPTOR	Q15759	MAPK11	T917	A914V	914	Missense	distal	-3	no	46.103	46.736	EPSD	ICGC;COSMIC	33.886	Up-regulation
CMGC_MAPK_p38_MAPK11_ST	Q01094	E2F1	Q15759	MAPK11	S121	S121F	121	Missense	central	0	yes	46.718	0.000	EPSD	ICGC;COSMIC;CCLE	33.886	Loss
CMGC_MAPK_p38_MAPK11_ST	Q01094	E2F1	Q15759	MAPK11	S121	P122L	122	Missense	proximal	1	no	46.718	36.901	EPSD	ICGC	33.886	Down-regulation
CMGC_MAPK_p38_MAPK11_ST	Q01094	E2F1	Q15759	MAPK11	S131	R138H	138	Missense	distal	7	no	38.340	38.209	EPSD	ICGC;COSMIC	33.886	Down-regulation
CMGC_MAPK_p38_MAPK11_ST	Q01094	E2F1	Q15759	MAPK11	S307	P308T	308	Missense	proximal	1	no	34.651	10.067	EPSD	ICGC	33.886	Loss
CMGC_MAPK_p38_MAPK11_ST	Q01094	E2F1	Q15759	MAPK11	S307	G305W	305	Missense	proximal	-2	no	34.651	34.861	EPSD	ICGC;COSMIC	33.886	Up-regulation
CMGC_MAPK_p38_MAPK11_ST	Q01094	E2F1	Q15759	MAPK11	S307	G305V	305	Missense	proximal	-2	no	34.651	34.923	EPSD	ICGC;COSMIC	33.886	Up-regulation
CMGC_MAPK_p38_MAPK11_ST	Q01094	E2F1	Q15759	MAPK11	T311	P308T	308	Missense	distal	-3	no	37.432	37.621	EPSD	ICGC	33.886	Up-regulation
CMGC_MAPK_p38_MAPK11_ST	Q01094	E2F1	Q15759	MAPK11	T311	G305W	305	Missense	distal	-6	no	37.432	37.398	EPSD	ICGC;COSMIC	33.886	Down-regulation
CMGC_MAPK_p38_MAPK11_ST	Q01094	E2F1	Q15759	MAPK11	T311	S318A	318	Missense	distal	7	no	37.432	36.732	EPSD	ICGC	33.886	Down-regulation
CMGC_MAPK_p38_MAPK11_ST	Q01094	E2F1	Q15759	MAPK11	T311	G305V	305	Missense	distal	-6	no	37.432	37.312	EPSD	ICGC;COSMIC	33.886	Down-regulation
CMGC_MAPK_p38_MAPK11_ST	Q01094	E2F1	Q15759	MAPK11	T317	S318A	318	Missense	proximal	1	no	31.502	37.966	EPSD	ICGC	33.886	Gain
CMGC_MAPK_p38_MAPK11_ST	Q01094	E2F1	Q15759	MAPK11	S375	V369M	369	Missense	distal	-6	no	42.829	42.963	EPSD	ICGC	33.886	Up-regulation
CMGC_MAPK_p38_MAPK11_ST	Q01094	E2F1	Q15759	MAPK11	S403	A408V	408	Missense	distal	5	no	47.567	48.219	EPSD;PhosphoSitePlus	ICGC;COSMIC	33.886	Up-regulation
CMGC_MAPK_p38_MAPK11_ST	Q01094	E2F1	Q15759	MAPK11	S403	E397K	397	Missense	distal	-6	no	47.567	47.607	EPSD;PhosphoSitePlus	ICGC;COSMIC	33.886	Up-regulation
CMGC_MAPK_p38_MAPK11_ST	P00533	EGFR	Q15759	MAPK11	S511	V505L	505	Missense	distal	-6	no	42.006	42.137	EPSD	ICGC;COSMIC	33.886	Up-regulation
CMGC_MAPK_p38_MAPK11_ST	P00533	EGFR	Q15759	MAPK11	S511	C510R	510	Missense	proximal	-1	no	42.006	42.842	EPSD	ICGC;COSMIC	33.886	Up-regulation
CMGC_MAPK_p38_MAPK11_ST	P00533	EGFR	Q15759	MAPK11	T693	A698T	698	Missense	distal	5	no	43.228	43.618	EPSD	ICGC;COSMIC	33.886	Up-regulation
CMGC_MAPK_p38_MAPK11_ST	P00533	EGFR	Q15759	MAPK11	S991	R986Q	986	Missense	distal	-5	no	37.298	37.255	EPSD	ICGC;COSMIC	33.886	Down-regulation
CMGC_MAPK_p38_MAPK11_ST	P00533	EGFR	Q15759	MAPK11	S991	S991R	991	Missense	central	0	yes	37.298	0.000	EPSD	ICGC;COSMIC	33.886	Loss
CMGC_MAPK_p38_MAPK11_ST	P00533	EGFR	Q15759	MAPK11	S991	L989I	989	Missense	proximal	-2	no	37.298	36.544	EPSD	ICGC;COSMIC	33.886	Down-regulation
CMGC_MAPK_p38_MAPK11_ST	P00533	EGFR	Q15759	MAPK11	S1153	A1155T	1155	Missense	proximal	2	no	31.565	34.146	EPSD	ICGC	33.886	Gain
CMGC_MAPK_p38_MAPK11_ST	Q8IW41	MAPKAPK5	Q15759	MAPK11	S212	Y218C	218	Missense	distal	6	no	39.481	39.565	EPSD	ICGC	33.886	Up-regulation
CMGC_MAPK_p38_MAPK11_ST	Q8IW41	MAPKAPK5	Q15759	MAPK11	S212	G207V	207	Missense	distal	-5	no	39.481	39.251	EPSD	ICGC	33.886	Down-regulation
CMGC_MAPK_p38_MAPK11_ST	Q8IW41	MAPKAPK5	Q15759	MAPK11	T214	Y218C	218	Missense	distal	4	no	41.160	39.918	EPSD	ICGC	33.886	Down-regulation
CMGC_MAPK_p38_MAPK11_ST	Q8IW41	MAPKAPK5	Q15759	MAPK11	T214	G207V	207	Missense	distal	-7	no	41.160	41.074	EPSD	ICGC	33.886	Down-regulation
CMGC_MAPK_p38_MAPK11_ST	Q8IW41	MAPKAPK5	Q15759	MAPK11	S348	V347A	347	Missense	proximal	-1	no	33.722	34.464	EPSD	ICGC;COSMIC	33.886	Gain
CMGC_MAPK_p38_MAPK11_ST	P30305	CDC25B	Q15759	MAPK11	S15	S12W	12	Missense	distal	-3	no	40.733	41.457	EPSD	ICGC;COSMIC	33.886	Up-regulation
CMGC_MAPK_p38_MAPK11_ST	P30305	CDC25B	Q15759	MAPK11	S15	P8S	8	Missense	distal	-7	no	40.733	40.872	EPSD	ICGC;COSMIC	33.886	Up-regulation
CMGC_MAPK_p38_MAPK11_ST	P30305	CDC25B	Q15759	MAPK11	S15	L14V	14	Missense	proximal	-1	no	40.733	40.380	EPSD	ICGC;COSMIC	33.886	Down-regulation
CMGC_MAPK_p38_MAPK11_ST	P30305	CDC25B	Q15759	MAPK11	S50	R45W	45	Missense	distal	-5	no	35.045	34.957	EPSD	ICGC;COSMIC	33.886	Down-regulation
CMGC_MAPK_p38_MAPK11_ST	P30305	CDC25B	Q15759	MAPK11	T69	S67R	67	Missense	proximal	-2	no	38.212	37.541	EPSD	ICGC	33.886	Down-regulation
CMGC_MAPK_p38_MAPK11_ST	P30305	CDC25B	Q15759	MAPK11	S115	D120Y	120	Missense	distal	5	no	53.047	52.704	EPSD	ICGC	33.886	Down-regulation
CMGC_MAPK_p38_MAPK11_ST	P30305	CDC25B	Q15759	MAPK11	S117	D120Y	120	Missense	distal	3	no	43.493	43.002	EPSD	ICGC	33.886	Down-regulation
CMGC_MAPK_p38_MAPK11_ST	P30305	CDC25B	Q15759	MAPK11	S238	P232T	232	Missense	distal	-6	no	38.938	38.923	EPSD	ICGC;COSMIC	33.886	Down-regulation
CMGC_MAPK_p38_MAPK11_ST	P30305	CDC25B	Q15759	MAPK11	S249	E247D	247	Missense	proximal	-2	no	45.401	45.350	PhosphoSitePlus	ICGC;COSMIC	33.886	Down-regulation
CMGC_MAPK_p38_MAPK11_ST	P30305	CDC25B	Q15759	MAPK11	S321	M324R	324	Missense	distal	3	no	45.485	45.518	EPSD	ICGC;COSMIC	33.886	Up-regulation
CMGC_MAPK_p38_MAPK11_ST	P30305	CDC25B	Q15759	MAPK11	S321	R320C	320	Missense	proximal	-1	no	45.485	44.649	EPSD	ICGC	33.886	Down-regulation
CMGC_MAPK_p38_MAPK11_ST	P30305	CDC25B	Q15759	MAPK11	S375	E382G	382	Missense	distal	7	no	37.282	36.891	EPSD	ICGC;COSMIC	33.886	Down-regulation
CMGC_MAPK_p38_MAPK11_ST	P30305	CDC25B	Q15759	MAPK11	S470	E464Q	464	Missense	distal	-6	no	41.932	41.885	EPSD	ICGC;COSMIC	33.886	Down-regulation
CMGC_MAPK_p38_MAPK11_ST	P41235	HNF4A	Q15759	MAPK11	S147	I152F	152	Missense	distal	5	no	37.117	37.018	EPSD	ICGC;COSMIC	33.886	Down-regulation
CMGC_MAPK_p38_MAPK11_ST	P41235	HNF4A	Q15759	MAPK11	S147	S148C	148	Missense	proximal	1	no	37.117	11.069	EPSD	ICGC;COSMIC	33.886	Loss
CMGC_MAPK_p38_MAPK11_ST	P41235	HNF4A	Q15759	MAPK11	S147	S148I	148	Missense	proximal	1	no	37.117	3.824	EPSD	ICGC	33.886	Loss
CMGC_MAPK_p38_MAPK11_ST	P41235	HNF4A	Q15759	MAPK11	S148	I152F	152	Missense	distal	4	no	33.292	34.778	EPSD	ICGC;COSMIC	33.886	Gain
CMGC_MAPK_p38_MAPK11_ST	P41235	HNF4A	Q15759	MAPK11	S167	G174C	174	Missense	distal	7	no	47.102	46.133	PhosphoSitePlus	ICGC	33.886	Down-regulation
CMGC_MAPK_p38_MAPK11_ST	P41235	HNF4A	Q15759	MAPK11	S167	V169I	169	Missense	proximal	2	no	47.102	46.325	PhosphoSitePlus	ICGC;GDSC	33.886	Down-regulation
CMGC_MAPK_p38_MAPK11_ST	P41235	HNF4A	Q15759	MAPK11	S378	M373L	373	Missense	distal	-5	no	41.933	41.814	EPSD	ICGC;COSMIC	33.886	Down-regulation
CMGC_MAPK_p38_MAPK11_ST	P41235	HNF4A	Q15759	MAPK11	S378	G377R	377	Missense	proximal	-1	no	41.933	41.819	EPSD	ICGC;COSMIC	33.886	Down-regulation
CMGC_MAPK_p38_MAPK11_ST	P41235	HNF4A	Q15759	MAPK11	S378	S380R	380	Missense	proximal	2	no	41.933	41.188	EPSD	ICGC;COSMIC	33.886	Down-regulation
CMGC_MAPK_p38_MAPK11_ST	P41235	HNF4A	Q15759	MAPK11	T429	P423S	423	Missense	distal	-6	no	35.953	36.048	EPSD	ICGC;COSMIC	33.886	Up-regulation
CMGC_MAPK_p38_MAPK11_ST	P17544	ATF7	Q15759	MAPK11	T51	S44A	44	Missense	distal	-7	no	48.874	48.708	PhosphoSitePlus	ICGC;COSMIC	33.886	Down-regulation
CMGC_MAPK_p38_MAPK11_ST	P17544	ATF7	Q15759	MAPK11	S128	P122S	122	Missense	distal	-6	no	37.974	38.069	EPSD	ICGC;COSMIC	33.886	Up-regulation
CMGC_MAPK_p38_MAPK11_ST	P17544	ATF7	Q15759	MAPK11	S128	P129Q	129	Missense	proximal	1	no	37.974	5.832	EPSD	ICGC	33.886	Loss
CMGC_MAPK_p38_MAPK11_ST	P17544	ATF7	Q15759	MAPK11	S132	P129Q	129	Missense	distal	-3	no	36.141	36.210	EPSD	ICGC	33.886	Up-regulation
CMGC_MAPK_p38_MAPK11_ST	P17544	ATF7	Q15759	MAPK11	S136	P129Q	129	Missense	distal	-7	no	42.677	42.607	EPSD	ICGC	33.886	Down-regulation
CMGC_MAPK_p38_MAPK11_ST	P17544	ATF7	Q15759	MAPK11	T158	P164S	164	Missense	distal	6	no	43.279	43.271	EPSD	ICGC	33.886	Down-regulation
CMGC_MAPK_p38_MAPK11_ST	P17544	ATF7	Q15759	MAPK11	T179	Y173N	173	Missense	distal	-6	no	34.821	34.857	EPSD	ICGC;COSMIC	33.886	Up-regulation
CMGC_MAPK_p38_MAPK11_ST	P17544	ATF7	Q15759	MAPK11	T179	L180P	180	Missense	proximal	1	no	34.821	44.638	EPSD	ICGC;COSMIC	33.886	Up-regulation
CMGC_MAPK_p38_MAPK11_ST	P17544	ATF7	Q15759	MAPK11	T179	H177N	177	Missense	proximal	-2	no	34.821	35.032	EPSD	ICGC	33.886	Up-regulation
CMGC_MAPK_p38_MAPK11_ST	P17544	ATF7	Q15759	MAPK11	T179	L180I	180	Missense	proximal	1	no	34.821	-4.153	EPSD	ICGC;COSMIC	33.886	Loss
CMGC_MAPK_p38_MAPK11_ST	P17544	ATF7	Q15759	MAPK11	S182	L180P	180	Missense	proximal	-2	no	38.590	38.926	EPSD	ICGC;COSMIC	33.886	Up-regulation
CMGC_MAPK_p38_MAPK11_ST	P17544	ATF7	Q15759	MAPK11	S182	H177N	177	Missense	distal	-5	no	38.590	38.576	EPSD	ICGC	33.886	Down-regulation
CMGC_MAPK_p38_MAPK11_ST	P17544	ATF7	Q15759	MAPK11	S182	L180I	180	Missense	proximal	-2	no	38.590	37.836	EPSD	ICGC;COSMIC	33.886	Down-regulation
CMGC_MAPK_p38_MAPK11_ST	P17544	ATF7	Q15759	MAPK11	S199	P205H	205	Missense	distal	6	no	38.754	38.796	EPSD	ICGC	33.886	Up-regulation
CMGC_MAPK_p38_MAPK11_ST	P17544	ATF7	Q15759	MAPK11	S257	G260D	260	Missense	distal	3	no	44.201	44.176	EPSD	ICGC;COSMIC	33.886	Down-regulation
CMGC_MAPK_p38_MAPK11_ST	P17544	ATF7	Q15759	MAPK11	S257	N251K	251	Missense	distal	-6	no	44.201	44.223	EPSD	ICGC	33.886	Up-regulation
CMGC_MAPK_p38_MAPK11_ST	P17544	ATF7	Q15759	MAPK11	S322	T327N	327	Missense	distal	5	no	41.778	41.975	EPSD	ICGC	33.886	Up-regulation
CMGC_MAPK_p38_MAPK11_ST	P17544	ATF7	Q15759	MAPK11	T327	T327N	327	Missense	central	0	yes	44.232	0.000	EPSD	ICGC	33.886	Loss
CMGC_MAPK_p38_MAPK11_ST	P17544	ATF7	Q15759	MAPK11	S424	Q419E	419	Missense	distal	-5	no	38.281	38.478	EPSD	ICGC;COSMIC	33.886	Up-regulation
CMGC_MAPK_p38_MAPK11_ST	P17544	ATF7	Q15759	MAPK11	S424	T418N	418	Missense	distal	-6	no	38.281	38.309	EPSD	ICGC	33.886	Up-regulation
CMGC_MAPK_p38_MAPK11_ST	P17544	ATF7	Q15759	MAPK11	S424	Q419R	419	Missense	distal	-5	no	38.281	38.324	EPSD	ICGC;COSMIC	33.886	Up-regulation
CMGC_MAPK_p38_MAPK11_ST	P17544	ATF7	Q15759	MAPK11	S434	A436T	436	Missense	proximal	2	no	36.764	39.345	EPSD	ICGC;COSMIC	33.886	Up-regulation
CMGC_MAPK_p38_MAPK11_ST	P17544	ATF7	Q15759	MAPK11	S434	T432R	432	Missense	proximal	-2	no	36.764	35.896	EPSD	ICGC;COSMIC	33.886	Down-regulation
CMGC_MAPK_p38_MAPK11_ST	P17544	ATF7	Q15759	MAPK11	S443	A436T	436	Missense	distal	-7	no	34.985	35.130	EPSD	ICGC;COSMIC	33.886	Up-regulation
CMGC_MAPK_p38_MAPK11_ST	P17544	ATF7	Q15759	MAPK11	T486	S491F	491	Missense	distal	5	no	36.749	37.556	EPSD	ICGC;COSMIC	33.886	Up-regulation
CMGC_MAPK_p38_MAPK11_ST	P17544	ATF7	Q15759	MAPK11	T486	S481L	481	Missense	distal	-5	no	36.749	36.450	EPSD	ICGC;COSMIC;CCLE	33.886	Down-regulation
CMGC_MAPK_p38_MAPK11_ST	P17544	ATF7	Q15759	MAPK11	T486	Q488K	488	Missense	proximal	2	no	36.749	37.183	EPSD	ICGC	33.886	Up-regulation
CMGC_MAPK_p38_MAPK11_ST	Q02156	PRKCE	Q15759	MAPK11	T309	G307D	307	Missense	proximal	-2	no	43.170	43.499	EPSD	ICGC	33.886	Up-regulation
CMGC_MAPK_p38_MAPK11_ST	Q02156	PRKCE	Q15759	MAPK11	T309	V302L	302	Missense	distal	-7	no	43.170	43.174	EPSD	ICGC	33.886	Up-regulation
CMGC_MAPK_p38_MAPK11_ST	Q02156	PRKCE	Q15759	MAPK11	T309	N315S	315	Missense	distal	6	no	43.170	43.124	EPSD	ICGC;COSMIC	33.886	Down-regulation
CMGC_MAPK_p38_MAPK11_ST	Q02156	PRKCE	Q15759	MAPK11	S381	Q385H	385	Missense	distal	4	no	48.729	47.881	EPSD	ICGC;COSMIC	33.886	Down-regulation
CMGC_MAPK_p38_MAPK11_ST	Q02156	PRKCE	Q15759	MAPK11	S388	Q385H	385	Missense	distal	-3	no	39.349	39.861	EPSD	ICGC;COSMIC	33.886	Up-regulation
CMGC_MAPK_p38_MAPK11_ST	Q02156	PRKCE	Q15759	MAPK11	S388	E394K	394	Missense	distal	6	no	39.349	39.347	EPSD	ICGC;COSMIC;GDSC	33.886	Down-regulation
CMGC_MAPK_p38_MAPK11_ST	Q02156	PRKCE	Q15759	MAPK11	T566	F567L	567	Missense	proximal	1	no	-0.667	36.948	EPSD	ICGC	33.886	Gain
CMGC_MAPK_p38_MAPK11_ST	Q01844	EWSR1	Q15759	MAPK11	S259	S255G	255	Missense	distal	-4	no	34.104	32.100	EPSD	ICGC;COSMIC	33.886	Loss
CMGC_MAPK_p38_MAPK11_ST	P30281	CCND3	Q15759	MAPK11	S262	S259A	259	Missense	distal	-3	no	33.567	33.980	EPSD	ICGC;COSMIC	33.886	Gain
CMGC_MAPK_p38_MAPK11_ST	P30281	CCND3	Q15759	MAPK11	S264	S259A	259	Missense	distal	-5	no	37.891	37.807	EPSD	ICGC;COSMIC	33.886	Down-regulation
CMGC_MAPK_p38_MAPK11_ST	P30281	CCND3	Q15759	MAPK11	S264	A266E	266	Missense	proximal	2	no	37.891	38.888	EPSD	ICGC;COSMIC	33.886	Up-regulation
CMGC_MAPK_p38_MAPK11_ST	P30281	CCND3	Q15759	MAPK11	S264	S262I	262	Missense	proximal	-2	no	37.891	36.862	EPSD	ICGC;COSMIC	33.886	Down-regulation
CMGC_MAPK_p38_MAPK11_ST	P30281	CCND3	Q15759	MAPK11	T281	T283P	283	Missense	proximal	2	no	34.875	33.491	EPSD	ICGC;COSMIC	33.886	Loss
CMGC_MAPK_p38_MAPK11_ST	P30281	CCND3	Q15759	MAPK11	T281	D286A	286	Missense	distal	5	no	34.875	34.302	EPSD	ICGC	33.886	Down-regulation
CMGC_MAPK_p38_MAPK11_ST	P30281	CCND3	Q15759	MAPK11	S282	T283P	283	Missense	proximal	1	no	27.607	52.192	EPSD	ICGC;COSMIC	33.886	Gain
CMGC_MAPK_p38_MAPK11_ST	P30281	CCND3	Q15759	MAPK11	T283	A289D	289	Missense	distal	6	no	51.057	51.072	PhosphoSitePlus	ICGC	33.886	Up-regulation
CMGC_MAPK_p38_MAPK11_ST	P30281	CCND3	Q15759	MAPK11	T283	I290K	290	Missense	distal	7	no	51.057	52.165	PhosphoSitePlus	ICGC;COSMIC;CCLE	33.886	Up-regulation
CMGC_MAPK_p38_MAPK11_ST	P30281	CCND3	Q15759	MAPK11	T283	I290T	290	Missense	distal	7	no	51.057	52.005	PhosphoSitePlus	ICGC;COSMIC;CCLE	33.886	Up-regulation
CMGC_MAPK_p38_MAPK11_ST	P30281	CCND3	Q15759	MAPK11	T283	T283P	283	Missense	central	0	yes	51.057	0.000	PhosphoSitePlus	ICGC;COSMIC	33.886	Loss
CMGC_MAPK_p38_MAPK11_ST	P30281	CCND3	Q15759	MAPK11	T283	D286A	286	Missense	distal	3	no	51.057	50.325	PhosphoSitePlus	ICGC	33.886	Down-regulation
CMGC_MAPK_p38_MAPK11_ST	P30281	CCND3	Q15759	MAPK11	T285	D286A	286	Missense	proximal	1	no	14.326	45.144	EPSD	ICGC	33.886	Gain
CMGC_MAPK_p38_MAPK11_ST	P30281	CCND3	Q15759	MAPK11	T288	A289D	289	Missense	proximal	1	no	38.653	7.834	EPSD	ICGC	33.886	Loss
CMGC_MAPK_p38_MAPK11_ST	P30281	CCND3	Q15759	MAPK11	T288	I290K	290	Missense	proximal	2	no	38.653	40.800	EPSD	ICGC;COSMIC;CCLE	33.886	Up-regulation
CMGC_MAPK_p38_MAPK11_ST	P30281	CCND3	Q15759	MAPK11	T288	I290T	290	Missense	proximal	2	no	38.653	41.816	EPSD	ICGC;COSMIC;CCLE	33.886	Up-regulation
CMGC_MAPK_p38_MAPK11_ST	P30281	CCND3	Q15759	MAPK11	T288	T283P	283	Missense	distal	-5	no	38.653	38.573	EPSD	ICGC;COSMIC	33.886	Down-regulation
CMGC_MAPK_p38_MAPK11_ST	P30281	CCND3	Q15759	MAPK11	T288	D286A	286	Missense	proximal	-2	no	38.653	38.749	EPSD	ICGC	33.886	Up-regulation
CMGC_MAPK_p38_MAPK11_ST	P04150	NR3C1	Q15759	MAPK11	S45	A49D	49	Missense	distal	4	no	37.002	36.630	EPSD	ICGC	33.886	Down-regulation
CMGC_MAPK_p38_MAPK11_ST	P04150	NR3C1	Q15759	MAPK11	T145	N138K	138	Missense	distal	-7	no	37.721	37.836	EPSD	ICGC	33.886	Up-regulation
CMGC_MAPK_p38_MAPK11_ST	P04150	NR3C1	Q15759	MAPK11	S226	E221K	221	Missense	distal	-5	no	50.001	50.017	PhosphoSitePlus	ICGC;COSMIC	33.886	Up-regulation
CMGC_MAPK_p38_MAPK11_ST	P04150	NR3C1	Q15759	MAPK11	S226	E231K	231	Missense	distal	5	no	50.001	49.900	PhosphoSitePlus	ICGC;COSMIC	33.886	Down-regulation
CMGC_MAPK_p38_MAPK11_ST	P04150	NR3C1	Q15759	MAPK11	S267	S269G	269	Missense	proximal	2	no	41.419	39.380	EPSD	ICGC	33.886	Down-regulation
CMGC_MAPK_p38_MAPK11_ST	P04150	NR3C1	Q15759	MAPK11	S267	S269N	269	Missense	proximal	2	no	41.419	41.206	EPSD	ICGC;COSMIC	33.886	Down-regulation
CMGC_MAPK_p38_MAPK11_ST	P04150	NR3C1	Q15759	MAPK11	S404	T411S	411	Missense	distal	7	no	37.425	37.791	EPSD	ICGC;COSMIC	33.886	Up-regulation
CMGC_MAPK_p38_MAPK11_ST	P04150	NR3C1	Q15759	MAPK11	S407	T411S	411	Missense	distal	4	no	33.686	34.036	EPSD	ICGC;COSMIC	33.886	Gain
TK_EGFR_ERBB4_Y	Q15303	ERBB4	Q15303	ERBB4	Y1056	Y1056H	1056	Missense	central	0	yes	0.000	0.000	PhosphoSitePlus;EPSD	ICGC	0.000	Loss
Other_NKF2_PINK1_ST	Q6NUN9	ZNF746	Q9BXM7	PINK1	T278	K282N	282	Missense	distal	4	no	12.917	12.744	EPSD	ICGC;COSMIC	11.649	Down-regulation
Other_NKF2_PINK1_ST	Q6NUN9	ZNF746	Q9BXM7	PINK1	T278	V281I	281	Missense	distal	3	no	12.917	11.224	EPSD	ICGC	11.649	Loss
Other_NKF2_PINK1_ST	Q6NUN9	ZNF746	Q9BXM7	PINK1	S322	A324S	324	Missense	proximal	2	no	24.807	24.489	PhosphoSitePlus;EPSD	ICGC;COSMIC	11.649	Down-regulation
Other_NKF2_PINK1_ST	Q6NUN9	ZNF746	Q9BXM7	PINK1	S322	Q325R	325	Missense	distal	3	no	24.807	23.762	PhosphoSitePlus;EPSD	ICGC	11.649	Down-regulation
Other_NKF2_PINK1_ST	Q6NUN9	ZNF746	Q9BXM7	PINK1	S322	Q325K	325	Missense	distal	3	no	24.807	25.167	PhosphoSitePlus;EPSD	ICGC	11.649	Up-regulation
Other_NKF2_PINK1_ST	Q6NUN9	ZNF746	Q9BXM7	PINK1	S322	W329L	329	Missense	distal	7	no	24.807	25.009	PhosphoSitePlus;EPSD	ICGC;COSMIC	11.649	Up-regulation
Other_NKF2_PINK1_ST	Q6NUN9	ZNF746	Q9BXM7	PINK1	S322	W329R	329	Missense	distal	7	no	24.807	24.590	PhosphoSitePlus;EPSD	ICGC;COSMIC	11.649	Down-regulation
Other_NKF2_PINK1_ST	Q6NUN9	ZNF746	Q9BXM7	PINK1	S359	V362M	362	Missense	distal	3	no	12.836	12.130	EPSD	ICGC;COSMIC	11.649	Down-regulation
Other_NKF2_PINK1_ST	Q6NUN9	ZNF746	Q9BXM7	PINK1	S359	P360T	360	Missense	proximal	1	no	12.836	11.380	EPSD	ICGC	11.649	Loss
Other_NKF2_PINK1_ST	Q6NUN9	ZNF746	Q9BXM7	PINK1	S359	E366D	366	Missense	distal	7	no	12.836	13.015	EPSD	ICGC;COSMIC	11.649	Up-regulation
Other_NKF2_PINK1_ST	Q6NUN9	ZNF746	Q9BXM7	PINK1	S359	A361V	361	Missense	proximal	2	no	12.836	12.824	EPSD	ICGC;COSMIC	11.649	Down-regulation
Other_NKF2_PINK1_ST	Q6NUN9	ZNF746	Q9BXM7	PINK1	S499	G495S	495	Missense	distal	-4	no	13.659	14.055	EPSD	ICGC	11.649	Up-regulation
Other_NKF2_PINK1_ST	Q6NUN9	ZNF746	Q9BXM7	PINK1	S499	A504T	504	Missense	distal	5	no	13.659	12.604	EPSD	ICGC	11.649	Down-regulation
Other_NKF2_PINK1_ST	Q6NUN9	ZNF746	Q9BXM7	PINK1	S613	P608S	608	Missense	distal	-5	no	25.266	22.511	EPSD;PhosphoSitePlus	ICGC;COSMIC	11.649	Down-regulation
Other_NKF2_PINK1_ST	Q6NUN9	ZNF746	Q9BXM7	PINK1	S613	A615T	615	Missense	proximal	2	no	25.266	25.325	EPSD;PhosphoSitePlus	ICGC;COSMIC	11.649	Up-regulation
Other_NKF2_PINK1_ST	O95202	LETM1	Q9BXM7	PINK1	T192	R193H	193	Missense	proximal	1	no	25.697	24.356	PhosphoSitePlus	ICGC;COSMIC	11.649	Down-regulation
Other_NKF2_PINK1_ST	O95202	LETM1	Q9BXM7	PINK1	T436	Q432H	432	Missense	distal	-4	no	11.947	11.858	EPSD	ICGC;COSMIC	11.649	Down-regulation
Other_NKF2_PINK1_ST	O95202	LETM1	Q9BXM7	PINK1	T541	K536N	536	Missense	distal	-5	no	7.164	13.660	EPSD	ICGC;COSMIC	11.649	Gain
Other_NKF2_PINK1_ST	O95202	LETM1	Q9BXM7	PINK1	S561	L562I	562	Missense	proximal	1	no	10.774	11.984	EPSD	ICGC	11.649	Gain
Other_NKF2_PINK1_ST	Q9BXM7	PINK1	Q9BXM7	PINK1	T257	K260R	260	Missense	distal	3	no	24.042	22.637	EPSD;PhosphoSitePlus	ICGC;COSMIC	11.649	Down-regulation
Other_NKF2_PINK1_ST	Q9BXM7	PINK1	Q9BXM7	PINK1	T257	G254V	254	Missense	distal	-3	no	24.042	24.041	EPSD;PhosphoSitePlus	ICGC	11.649	Down-regulation
Other_NKF2_PINK1_ST	Q9BXM7	PINK1	Q9BXM7	PINK1	T257	G251W	251	Missense	distal	-6	no	24.042	23.740	EPSD;PhosphoSitePlus	ICGC	11.649	Down-regulation
Other_NKF2_PINK1_ST	Q8IXI2	RHOT1	Q9BXM7	PINK1	S156	A162S	162	Missense	distal	6	no	26.785	26.084	PhosphoSitePlus	ICGC	11.649	Down-regulation
Other_NKF2_PINK1_ST	Q8IXI2	RHOT1	Q9BXM7	PINK1	S156	L152P	152	Missense	distal	-4	no	26.785	26.291	PhosphoSitePlus	ICGC;COSMIC;GDSC;CCLE	11.649	Down-regulation
TKL_RAF_RAF_RAF1_ST	P04049	RAF1	P04049	RAF1	S204	S211Y	211	Missense	distal	7	no	10.128	10.425	EPSD	ICGC	7.934	Up-regulation
TKL_RAF_RAF_RAF1_ST	P04049	RAF1	P04049	RAF1	S204	G205V	205	Missense	proximal	1	no	10.128	9.631	EPSD	ICGC;COSMIC	7.934	Down-regulation
TKL_RAF_RAF_RAF1_ST	P04049	RAF1	P04049	RAF1	S204	P207T	207	Missense	distal	3	no	10.128	9.787	EPSD	ICGC;COSMIC	7.934	Down-regulation
TKL_RAF_RAF_RAF1_ST	P04049	RAF1	P04049	RAF1	S220	V226D	226	Missense	distal	6	no	8.780	8.463	EPSD	ICGC;COSMIC	7.934	Down-regulation
TKL_RAF_RAF_RAF1_ST	P04049	RAF1	P04049	RAF1	S220	M224I	224	Missense	distal	4	no	8.780	8.810	EPSD	ICGC;COSMIC	7.934	Up-regulation
TKL_RAF_RAF_RAF1_ST	P04049	RAF1	P04049	RAF1	S220	S220C	220	Missense	central	0	yes	8.780	0.000	EPSD	ICGC	7.934	Loss
TKL_RAF_RAF_RAF1_ST	P04049	RAF1	P04049	RAF1	S220	R218L	218	Missense	proximal	-2	no	8.780	8.907	EPSD	ICGC;COSMIC	7.934	Up-regulation
TKL_RAF_RAF_RAF1_ST	P04049	RAF1	P04049	RAF1	S227	V226D	226	Missense	proximal	-1	no	8.404	8.461	EPSD	ICGC;COSMIC	7.934	Up-regulation
TKL_RAF_RAF_RAF1_ST	P04049	RAF1	P04049	RAF1	S227	M224I	224	Missense	distal	-3	no	8.404	8.259	EPSD	ICGC;COSMIC	7.934	Down-regulation
TKL_RAF_RAF_RAF1_ST	P04049	RAF1	P04049	RAF1	S227	S220C	220	Missense	distal	-7	no	8.404	8.640	EPSD	ICGC	7.934	Up-regulation
TKL_RAF_RAF_RAF1_ST	Q92934	BAD	P04049	RAF1	S75	R72S	72	Missense	distal	-3	no	17.199	12.858	PhosphoSitePlus;EPSD	ICGC	7.934	Down-regulation
TKL_RAF_RAF_RAF1_ST	Q92934	BAD	P04049	RAF1	S75	T80K	80	Missense	distal	5	no	17.199	17.120	PhosphoSitePlus;EPSD	ICGC	7.934	Down-regulation
TKL_RAF_RAF_RAF1_ST	Q92934	BAD	P04049	RAF1	S75	S74G	74	Missense	proximal	-1	no	17.199	17.027	PhosphoSitePlus;EPSD	ICGC;COSMIC	7.934	Down-regulation
TKL_RAF_RAF_RAF1_ST	Q92934	BAD	P04049	RAF1	S99	S99L	99	Missense	central	0	yes	13.786	0.000	EPSD;PhosphoSitePlus	ICGC	7.934	Loss
TKL_RAF_RAF_RAF1_ST	Q92934	BAD	P04049	RAF1	S99	R94W	94	Missense	distal	-5	no	13.786	13.599	EPSD;PhosphoSitePlus	ICGC	7.934	Down-regulation
TKL_RAF_RAF_RAF1_ST	Q92934	BAD	P04049	RAF1	S118	R112S	112	Missense	distal	-6	no	14.641	14.673	EPSD;PhosphoSitePlus	ICGC	7.934	Up-regulation
TKL_RAF_RAF_RAF1_ST	Q92934	BAD	P04049	RAF1	S144	R149L	149	Missense	distal	5	no	12.633	12.617	EPSD	ICGC;COSMIC	7.934	Down-regulation
TKL_RAF_RAF_RAF1_ST	Q92934	BAD	P04049	RAF1	T148	R149L	149	Missense	proximal	1	no	8.089	8.137	EPSD	ICGC;COSMIC	7.934	Up-regulation
TKL_RAF_RAF_RAF1_ST	Q92934	BAD	P04049	RAF1	S164	S167F	167	Missense	distal	3	no	6.632	8.057	EPSD	ICGC	7.934	Gain
TKL_RAF_RAF_RAF1_ST	Q02750	MAP2K1	P04049	RAF1	S218	G225C	225	Missense	distal	7	no	14.805	14.942	EPSD;PhosphoSitePlus	ICGC	7.934	Up-regulation
TKL_RAF_RAF_RAF1_ST	Q02750	MAP2K1	P04049	RAF1	S218	L215I	215	Missense	distal	-3	no	14.805	15.761	EPSD;PhosphoSitePlus	ICGC;COSMIC	7.934	Up-regulation
TKL_RAF_RAF_RAF1_ST	Q02750	MAP2K1	P04049	RAF1	S222	G225C	225	Missense	distal	3	no	13.804	13.793	PhosphoSitePlus;EPSD	ICGC	7.934	Down-regulation
TKL_RAF_RAF_RAF1_ST	Q02750	MAP2K1	P04049	RAF1	S222	L215I	215	Missense	distal	-7	no	13.804	13.655	PhosphoSitePlus;EPSD	ICGC;COSMIC	7.934	Down-regulation
TKL_RAF_RAF_RAF1_ST	Q02750	MAP2K1	P04049	RAF1	T238	S241Y	241	Missense	distal	3	no	7.111	8.100	EPSD	ICGC;COSMIC	7.934	Gain
TKL_RAF_RAF_RAF1_ST	Q02750	MAP2K1	P04049	RAF1	T292	P288H	288	Missense	distal	-4	no	9.208	10.743	EPSD	ICGC;COSMIC	7.934	Up-regulation
TKL_RAF_RAF_RAF1_ST	Q02750	MAP2K1	P04049	RAF1	T292	G294W	294	Missense	proximal	2	no	9.208	9.650	EPSD	ICGC;COSMIC	7.934	Up-regulation
TKL_RAF_RAF_RAF1_ST	Q02750	MAP2K1	P04049	RAF1	T292	P296H	296	Missense	distal	4	no	9.208	9.978	EPSD	ICGC;COSMIC	7.934	Up-regulation
TKL_RAF_RAF_RAF1_ST	Q05639	EEF1A2	P04049	RAF1	S21	S21F	21	Missense	central	0	yes	12.629	0.000	PhosphoSitePlus	ICGC	7.934	Loss
TKL_RAF_RAF_RAF1_ST	Q05639	EEF1A2	P04049	RAF1	S21	V16M	16	Missense	distal	-5	no	12.629	12.694	PhosphoSitePlus	ICGC;COSMIC	7.934	Up-regulation
TKL_RAF_RAF_RAF1_ST	Q05639	EEF1A2	P04049	RAF1	T279	V278M	278	Missense	proximal	-1	no	10.255	10.603	EPSD	ICGC;COSMIC	7.934	Up-regulation
TKL_RAF_RAF_RAF1_ST	Q05639	EEF1A2	P04049	RAF1	T432	R427H	427	Missense	distal	-5	no	10.550	10.226	EPSD	ICGC;COSMIC	7.934	Down-regulation
TKL_RAF_RAF_RAF1_ST	Q05639	EEF1A2	P04049	RAF1	T432	A425T	425	Missense	distal	-7	no	10.550	10.800	EPSD	ICGC;COSMIC	7.934	Up-regulation
TKL_RAF_RAF_RAF1_ST	P01106	MYC	P04049	RAF1	S6	N9K	9	Missense	distal	3	no	8.735	7.959	EPSD	ICGC;COSMIC	7.934	Down-regulation
TKL_RAF_RAF_RAF1_ST	P01106	MYC	P04049	RAF1	T8	N9K	9	Missense	proximal	1	no	14.011	13.527	PhosphoSitePlus	ICGC;COSMIC	7.934	Down-regulation
TKL_RAF_RAF_RAF1_ST	O14974	PPP1R12A	P04049	RAF1	S472	R469H	469	Missense	distal	-3	no	8.586	0.980	EPSD	ICGC;COSMIC	7.934	Loss
TKL_RAF_RAF_RAF1_ST	O14974	PPP1R12A	P04049	RAF1	S472	G466C	466	Missense	distal	-6	no	8.586	8.576	EPSD	ICGC;COSMIC	7.934	Down-regulation
TKL_RAF_RAF_RAF1_ST	O14974	PPP1R12A	P04049	RAF1	S472	S478Y	478	Missense	distal	6	no	8.586	8.395	EPSD	ICGC;COSMIC	7.934	Down-regulation
TKL_RAF_RAF_RAF1_ST	O14974	PPP1R12A	P04049	RAF1	S585	T590I	590	Missense	distal	5	no	9.716	9.677	EPSD	ICGC;COSMIC	7.934	Down-regulation
TKL_RAF_RAF_RAF1_ST	O14974	PPP1R12A	P04049	RAF1	S585	S589G	589	Missense	distal	4	no	9.716	9.473	EPSD	ICGC	7.934	Down-regulation
TKL_RAF_RAF_RAF1_ST	O14974	PPP1R12A	P04049	RAF1	S585	A580D	580	Missense	distal	-5	no	9.716	9.501	EPSD	ICGC;COSMIC	7.934	Down-regulation
TKL_RAF_RAF_RAF1_ST	O14974	PPP1R12A	P04049	RAF1	S585	S591R	591	Missense	distal	6	no	9.716	9.509	EPSD	ICGC	7.934	Down-regulation
TKL_RAF_RAF_RAF1_ST	O14974	PPP1R12A	P04049	RAF1	S759	E764K	764	Missense	distal	5	no	9.199	9.153	EPSD	ICGC	7.934	Down-regulation
TKL_RAF_RAF_RAF1_ST	O14974	PPP1R12A	P04049	RAF1	S759	T765N	765	Missense	distal	6	no	9.199	9.131	EPSD	ICGC	7.934	Down-regulation
TKL_RAF_RAF_RAF1_ST	O14974	PPP1R12A	P04049	RAF1	T892	S896L	896	Missense	distal	4	no	11.068	10.270	EPSD	ICGC	7.934	Down-regulation
TKL_RAF_RAF_RAF1_ST	O14974	PPP1R12A	P04049	RAF1	S910	R917G	917	Missense	distal	7	no	10.625	10.341	EPSD	ICGC;COSMIC	7.934	Down-regulation
TKL_RAF_RAF_RAF1_ST	O14974	PPP1R12A	P04049	RAF1	S910	R907H	907	Missense	distal	-3	no	10.625	3.019	EPSD	ICGC;COSMIC	7.934	Loss
TKL_RAF_RAF_RAF1_ST	O14974	PPP1R12A	P04049	RAF1	S910	G909R	909	Missense	proximal	-1	no	10.625	10.539	EPSD	ICGC;COSMIC	7.934	Down-regulation
TKL_RAF_RAF_RAF1_ST	O14974	PPP1R12A	P04049	RAF1	S912	G909R	909	Missense	distal	-3	no	5.416	12.925	EPSD	ICGC;COSMIC	7.934	Gain
CAMK_MAPKAPK_MK2_MAPKAPK2_ST	Q8N5C8	TAB3	P49137	MAPKAPK2	S82	S83T	83	Missense	proximal	1	no	12.230	12.375	EPSD	ICGC;COSMIC	11.681	Up-regulation
CAMK_MAPKAPK_MK2_MAPKAPK2_ST	Q8N5C8	TAB3	P49137	MAPKAPK2	S82	N75K	75	Missense	distal	-7	no	12.230	12.220	EPSD	ICGC;COSMIC	11.681	Down-regulation
CAMK_MAPKAPK_MK2_MAPKAPK2_ST	Q8N5C8	TAB3	P49137	MAPKAPK2	S103	S103G	103	Missense	central	0	yes	12.834	0.000	EPSD	ICGC	11.681	Loss
CAMK_MAPKAPK_MK2_MAPKAPK2_ST	Q8N5C8	TAB3	P49137	MAPKAPK2	S103	Q110K	110	Missense	distal	7	no	12.834	12.974	EPSD	ICGC	11.681	Up-regulation
CAMK_MAPKAPK_MK2_MAPKAPK2_ST	Q8N5C8	TAB3	P49137	MAPKAPK2	S103	L98M	98	Missense	distal	-5	no	12.834	12.079	EPSD	ICGC	11.681	Down-regulation
CAMK_MAPKAPK_MK2_MAPKAPK2_ST	Q8N5C8	TAB3	P49137	MAPKAPK2	S126	P124T	124	Missense	proximal	-2	no	10.746	12.223	EPSD	ICGC;COSMIC	11.681	Gain
CAMK_MAPKAPK_MK2_MAPKAPK2_ST	Q8N5C8	TAB3	P49137	MAPKAPK2	S229	P227S	227	Missense	proximal	-2	no	9.120	12.352	EPSD	ICGC	11.681	Gain
CAMK_MAPKAPK_MK2_MAPKAPK2_ST	Q8N5C8	TAB3	P49137	MAPKAPK2	S385	T378K	378	Missense	distal	-7	no	18.895	18.965	EPSD	ICGC	11.681	Up-regulation
CAMK_MAPKAPK_MK2_MAPKAPK2_ST	Q8N5C8	TAB3	P49137	MAPKAPK2	S385	R382M	382	Missense	distal	-3	no	18.895	10.504	EPSD	ICGC;COSMIC	11.681	Loss
CAMK_MAPKAPK_MK2_MAPKAPK2_ST	Q8N5C8	TAB3	P49137	MAPKAPK2	S411	P418T	418	Missense	distal	7	no	12.529	12.714	EPSD	ICGC	11.681	Up-regulation
CAMK_MAPKAPK_MK2_MAPKAPK2_ST	Q8N5C8	TAB3	P49137	MAPKAPK2	S415	P420T	420	Missense	distal	5	no	17.875	17.749	EPSD	ICGC;COSMIC	11.681	Down-regulation
CAMK_MAPKAPK_MK2_MAPKAPK2_ST	Q8N5C8	TAB3	P49137	MAPKAPK2	S415	P418T	418	Missense	distal	3	no	17.875	17.954	EPSD	ICGC	11.681	Up-regulation
CAMK_MAPKAPK_MK2_MAPKAPK2_ST	Q8N5C8	TAB3	P49137	MAPKAPK2	S444	P437T	437	Missense	distal	-7	no	15.072	15.044	EPSD	ICGC	11.681	Down-regulation
CAMK_MAPKAPK_MK2_MAPKAPK2_ST	Q8N5C8	TAB3	P49137	MAPKAPK2	S444	P449T	449	Missense	distal	5	no	15.072	14.946	EPSD	ICGC	11.681	Down-regulation
CAMK_MAPKAPK_MK2_MAPKAPK2_ST	Q8N5C8	TAB3	P49137	MAPKAPK2	S492	P490Q	490	Missense	proximal	-2	no	10.873	11.846	EPSD	ICGC	11.681	Gain
CAMK_MAPKAPK_MK2_MAPKAPK2_ST	Q8N5C8	TAB3	P49137	MAPKAPK2	S504	R503K	503	Missense	proximal	-1	no	11.715	11.736	EPSD	ICGC;COSMIC	11.681	Up-regulation
CAMK_MAPKAPK_MK2_MAPKAPK2_ST	Q8N5C8	TAB3	P49137	MAPKAPK2	S506	R503K	503	Missense	distal	-3	no	18.386	13.262	PhosphoSitePlus	ICGC;COSMIC	11.681	Down-regulation
CAMK_MAPKAPK_MK2_MAPKAPK2_ST	Q8N5C8	TAB3	P49137	MAPKAPK2	S645	K649E	649	Missense	distal	4	no	16.864	17.045	EPSD	ICGC;COSMIC	11.681	Up-regulation
CAMK_MAPKAPK_MK2_MAPKAPK2_ST	Q8N5C8	TAB3	P49137	MAPKAPK2	S669	T670K	670	Missense	proximal	1	no	17.529	17.002	EPSD	ICGC;COSMIC	11.681	Down-regulation
CAMK_MAPKAPK_MK2_MAPKAPK2_ST	P30305	CDC25B	P49137	MAPKAPK2	S91	T86M	86	Missense	distal	-5	no	13.750	13.570	EPSD	ICGC;COSMIC	11.681	Down-regulation
CAMK_MAPKAPK_MK2_MAPKAPK2_ST	P30305	CDC25B	P49137	MAPKAPK2	S117	D120Y	120	Missense	distal	3	no	13.328	13.188	EPSD	ICGC	11.681	Down-regulation
CAMK_MAPKAPK_MK2_MAPKAPK2_ST	P30305	CDC25B	P49137	MAPKAPK2	S151	M152V	152	Missense	proximal	1	no	12.970	13.330	EPSD	ICGC;COSMIC	11.681	Up-regulation
CAMK_MAPKAPK_MK2_MAPKAPK2_ST	P30305	CDC25B	P49137	MAPKAPK2	T167	Q170H	170	Missense	distal	3	no	12.481	12.441	EPSD	ICGC;COSMIC	11.681	Down-regulation
CAMK_MAPKAPK_MK2_MAPKAPK2_ST	P30305	CDC25B	P49137	MAPKAPK2	S169	Q170H	170	Missense	proximal	1	no	12.723	12.787	PhosphoSitePlus;EPSD	ICGC;COSMIC	11.681	Up-regulation
CAMK_MAPKAPK_MK2_MAPKAPK2_ST	P30305	CDC25B	P49137	MAPKAPK2	S229	S229R	229	Missense	central	0	yes	12.727	0.000	EPSD	ICGC;COSMIC	11.681	Loss
CAMK_MAPKAPK_MK2_MAPKAPK2_ST	P30305	CDC25B	P49137	MAPKAPK2	S229	S230T	230	Missense	proximal	1	no	12.727	12.872	EPSD	ICGC;COSMIC	11.681	Up-regulation
CAMK_MAPKAPK_MK2_MAPKAPK2_ST	P30305	CDC25B	P49137	MAPKAPK2	S229	P232T	232	Missense	distal	3	no	12.727	12.806	EPSD	ICGC;COSMIC	11.681	Up-regulation
CAMK_MAPKAPK_MK2_MAPKAPK2_ST	P30305	CDC25B	P49137	MAPKAPK2	S230	S229R	229	Missense	proximal	-1	no	16.350	16.340	EPSD	ICGC;COSMIC	11.681	Down-regulation
CAMK_MAPKAPK_MK2_MAPKAPK2_ST	P30305	CDC25B	P49137	MAPKAPK2	S230	P232T	232	Missense	proximal	2	no	16.350	16.566	EPSD	ICGC;COSMIC	11.681	Up-regulation
CAMK_MAPKAPK_MK2_MAPKAPK2_ST	P30305	CDC25B	P49137	MAPKAPK2	S323	M324R	324	Missense	proximal	1	no	19.707	19.900	EPSD;PhosphoSitePlus	ICGC;COSMIC	11.681	Up-regulation
CAMK_MAPKAPK_MK2_MAPKAPK2_ST	P30305	CDC25B	P49137	MAPKAPK2	S323	R320C	320	Missense	distal	-3	no	19.707	11.307	EPSD;PhosphoSitePlus	ICGC	11.681	Loss
CAMK_MAPKAPK_MK2_MAPKAPK2_ST	P30305	CDC25B	P49137	MAPKAPK2	S327	M324R	324	Missense	distal	-3	no	5.670	14.060	EPSD	ICGC;COSMIC	11.681	Gain
CAMK_MAPKAPK_MK2_MAPKAPK2_ST	P30305	CDC25B	P49137	MAPKAPK2	S375	E382G	382	Missense	distal	7	no	19.277	18.995	EPSD;PhosphoSitePlus	ICGC;COSMIC	11.681	Down-regulation
CAMK_MAPKAPK_MK2_MAPKAPK2_ST	P30305	CDC25B	P49137	MAPKAPK2	T561	L554I	554	Missense	distal	-7	no	12.938	12.937	EPSD	ICGC	11.681	Down-regulation
CAMK_MAPKAPK_MK2_MAPKAPK2_ST	P30305	CDC25B	P49137	MAPKAPK2	T561	S563C	563	Missense	proximal	2	no	12.938	12.538	EPSD	ICGC;COSMIC	11.681	Down-regulation
CAMK_MAPKAPK_MK2_MAPKAPK2_ST	P30305	CDC25B	P49137	MAPKAPK2	T561	W564L	564	Missense	distal	3	no	12.938	12.929	EPSD	ICGC;COSMIC	11.681	Down-regulation
CAMK_MAPKAPK_MK2_MAPKAPK2_ST	P30305	CDC25B	P49137	MAPKAPK2	S563	S563C	563	Missense	central	0	yes	12.463	0.000	EPSD	ICGC;COSMIC	11.681	Loss
CAMK_MAPKAPK_MK2_MAPKAPK2_ST	P30305	CDC25B	P49137	MAPKAPK2	S563	W564L	564	Missense	proximal	1	no	12.463	12.769	EPSD	ICGC;COSMIC	11.681	Up-regulation
CAMK_MAPKAPK_MK2_MAPKAPK2_ST	P17302	GJA1	P49137	MAPKAPK2	S251	D245V	245	Missense	distal	-6	no	12.263	12.243	EPSD	ICGC	11.681	Down-regulation
CAMK_MAPKAPK_MK2_MAPKAPK2_ST	P17302	GJA1	P49137	MAPKAPK2	S251	A249V	249	Missense	proximal	-2	no	12.263	10.063	EPSD	ICGC;COSMIC;GDSC;CCLE	11.681	Loss
CAMK_MAPKAPK_MK2_MAPKAPK2_ST	P17302	GJA1	P49137	MAPKAPK2	S251	L254P	254	Missense	distal	3	no	12.263	12.372	EPSD	ICGC	11.681	Up-regulation
CAMK_MAPKAPK_MK2_MAPKAPK2_ST	P17302	GJA1	P49137	MAPKAPK2	S296	K303N	303	Missense	distal	7	no	16.244	16.149	EPSD	ICGC	11.681	Down-regulation
CAMK_MAPKAPK_MK2_MAPKAPK2_ST	P17302	GJA1	P49137	MAPKAPK2	S296	D292N	292	Missense	distal	-4	no	16.244	16.206	EPSD	ICGC	11.681	Down-regulation
CAMK_MAPKAPK_MK2_MAPKAPK2_ST	P17302	GJA1	P49137	MAPKAPK2	S296	R293I	293	Missense	distal	-3	no	16.244	10.955	EPSD	ICGC	11.681	Loss
CAMK_MAPKAPK_MK2_MAPKAPK2_ST	P17302	GJA1	P49137	MAPKAPK2	S296	T290N	290	Missense	distal	-6	no	16.244	16.332	EPSD	ICGC	11.681	Up-regulation
CAMK_MAPKAPK_MK2_MAPKAPK2_ST	P17302	GJA1	P49137	MAPKAPK2	S296	T290I	290	Missense	distal	-6	no	16.244	16.298	EPSD	ICGC;COSMIC	11.681	Up-regulation
CAMK_MAPKAPK_MK2_MAPKAPK2_ST	P17302	GJA1	P49137	MAPKAPK2	S296	V289L	289	Missense	distal	-7	no	16.244	16.242	EPSD	ICGC;COSMIC	11.681	Down-regulation
CAMK_MAPKAPK_MK2_MAPKAPK2_ST	P17302	GJA1	P49137	MAPKAPK2	S330	S328P	328	Missense	proximal	-2	no	12.334	9.103	EPSD	ICGC;COSMIC	11.681	Loss
CAMK_MAPKAPK_MK2_MAPKAPK2_ST	P17302	GJA1	P49137	MAPKAPK2	S330	A323T	323	Missense	distal	-7	no	12.334	12.313	EPSD	ICGC	11.681	Down-regulation
CAMK_MAPKAPK_MK2_MAPKAPK2_ST	P17302	GJA1	P49137	MAPKAPK2	S330	A323V	323	Missense	distal	-7	no	12.334	12.378	EPSD	ICGC;COSMIC;CCLE	11.681	Up-regulation
CAMK_MAPKAPK_MK2_MAPKAPK2_ST	P17302	GJA1	P49137	MAPKAPK2	S365	R362Q	362	Missense	distal	-3	no	16.040	10.276	EPSD	ICGC;COSMIC;GDSC	11.681	Loss
CAMK_MAPKAPK_MK2_MAPKAPK2_ST	P17302	GJA1	P49137	MAPKAPK2	S365	D360E	360	Missense	distal	-5	no	16.040	16.765	EPSD	ICGC;COSMIC	11.681	Up-regulation
CAMK_MAPKAPK_MK2_MAPKAPK2_ST	P17302	GJA1	P49137	MAPKAPK2	S365	R370H	370	Missense	distal	5	no	16.040	16.346	EPSD	ICGC;GDSC;CCLE	11.681	Up-regulation
CAMK_MAPKAPK_MK2_MAPKAPK2_ST	P17302	GJA1	P49137	MAPKAPK2	S369	R362Q	362	Missense	distal	-7	no	17.238	17.324	EPSD	ICGC;COSMIC;GDSC	11.681	Up-regulation
CAMK_MAPKAPK_MK2_MAPKAPK2_ST	P17302	GJA1	P49137	MAPKAPK2	S369	R370H	370	Missense	proximal	1	no	17.238	16.849	EPSD	ICGC;GDSC;CCLE	11.681	Down-regulation
CAMK_MAPKAPK_MK2_MAPKAPK2_ST	P17302	GJA1	P49137	MAPKAPK2	S373	D378N	378	Missense	distal	5	no	17.666	17.633	EPSD	ICGC	11.681	Down-regulation
CAMK_MAPKAPK_MK2_MAPKAPK2_ST	P17302	GJA1	P49137	MAPKAPK2	S373	R370H	370	Missense	distal	-3	no	17.666	12.907	EPSD	ICGC;GDSC;CCLE	11.681	Down-regulation
CAMK_MAPKAPK_MK2_MAPKAPK2_ST	P04792	HSPB1	P49137	MAPKAPK2	S74	A67T	67	Missense	distal	-7	no	13.380	13.359	EPSD	ICGC;COSMIC	11.681	Down-regulation
CAMK_MAPKAPK_MK2_MAPKAPK2_ST	P04792	HSPB1	P49137	MAPKAPK2	S158	T164A	164	Missense	distal	6	no	13.817	13.810	EPSD	ICGC;COSMIC	11.681	Down-regulation
CAMK_MAPKAPK_MK2_MAPKAPK2_ST	P04792	HSPB1	P49137	MAPKAPK2	S158	P159H	159	Missense	proximal	1	no	13.817	13.342	EPSD	ICGC;COSMIC;CCLE	11.681	Down-regulation
CAMK_MAPKAPK_MK2_MAPKAPK2_ST	P53667	LIMK1	P49137	MAPKAPK2	S286	S287C	287	Missense	proximal	1	no	13.115	12.877	EPSD	ICGC;COSMIC	11.681	Down-regulation
CAMK_MAPKAPK_MK2_MAPKAPK2_ST	P53667	LIMK1	P49137	MAPKAPK2	S298	R295Q	295	Missense	distal	-3	no	21.044	15.280	EPSD	ICGC;COSMIC	11.681	Down-regulation
CAMK_MAPKAPK_MK2_MAPKAPK2_ST	P53667	LIMK1	P49137	MAPKAPK2	S323	R325C	325	Missense	proximal	2	no	21.826	21.530	PhosphoSitePlus	ICGC;COSMIC	11.681	Down-regulation
CAMK_MAPKAPK_MK2_MAPKAPK2_ST	Q96J92	WNK4	P49137	MAPKAPK2	S47	G48E	48	Missense	proximal	1	no	16.734	17.237	EPSD	ICGC;COSMIC	11.681	Up-regulation
CAMK_MAPKAPK_MK2_MAPKAPK2_ST	Q96J92	WNK4	P49137	MAPKAPK2	S64	S64L	64	Missense	central	0	yes	19.045	0.000	EPSD	ICGC;COSMIC	11.681	Loss
CAMK_MAPKAPK_MK2_MAPKAPK2_ST	Q96J92	WNK4	P49137	MAPKAPK2	S64	S63I	63	Missense	proximal	-1	no	19.045	19.047	EPSD	ICGC;COSMIC	11.681	Up-regulation
CAMK_MAPKAPK_MK2_MAPKAPK2_ST	Q96J92	WNK4	P49137	MAPKAPK2	S64	G68V	68	Missense	distal	4	no	19.045	19.106	EPSD	ICGC;COSMIC	11.681	Up-regulation
CAMK_MAPKAPK_MK2_MAPKAPK2_ST	Q96J92	WNK4	P49137	MAPKAPK2	S680	S674Y	674	Missense	distal	-6	no	16.618	16.721	EPSD	ICGC;COSMIC	11.681	Up-regulation
CAMK_MAPKAPK_MK2_MAPKAPK2_ST	Q96J92	WNK4	P49137	MAPKAPK2	S680	R675Q	675	Missense	distal	-5	no	16.618	15.900	EPSD	ICGC;COSMIC	11.681	Down-regulation
CAMK_MAPKAPK_MK2_MAPKAPK2_ST	Q96J92	WNK4	P49137	MAPKAPK2	S680	R677Q	677	Missense	distal	-3	no	16.618	10.854	EPSD	ICGC	11.681	Loss
CAMK_MAPKAPK_MK2_MAPKAPK2_ST	Q96J92	WNK4	P49137	MAPKAPK2	S680	D686N	686	Missense	distal	6	no	16.618	16.625	EPSD	ICGC;COSMIC	11.681	Up-regulation
CAMK_MAPKAPK_MK2_MAPKAPK2_ST	Q96J92	WNK4	P49137	MAPKAPK2	S680	S680C	680	Missense	central	0	yes	16.618	0.000	EPSD	ICGC;COSMIC	11.681	Loss
CAMK_MAPKAPK_MK2_MAPKAPK2_ST	Q96J92	WNK4	P49137	MAPKAPK2	S682	R675Q	675	Missense	distal	-7	no	12.775	12.862	EPSD	ICGC;COSMIC	11.681	Up-regulation
CAMK_MAPKAPK_MK2_MAPKAPK2_ST	Q96J92	WNK4	P49137	MAPKAPK2	S682	R677Q	677	Missense	distal	-5	no	12.775	12.057	EPSD	ICGC	11.681	Down-regulation
CAMK_MAPKAPK_MK2_MAPKAPK2_ST	Q96J92	WNK4	P49137	MAPKAPK2	S682	S680C	680	Missense	proximal	-2	no	12.775	9.297	EPSD	ICGC;COSMIC	11.681	Loss
CAMK_MAPKAPK_MK2_MAPKAPK2_ST	Q96J92	WNK4	P49137	MAPKAPK2	S728	R730Q	730	Missense	proximal	2	no	11.762	11.458	EPSD	ICGC;COSMIC	11.681	Loss
CAMK_MAPKAPK_MK2_MAPKAPK2_ST	Q96J92	WNK4	P49137	MAPKAPK2	S728	E723D	723	Missense	distal	-5	no	11.762	11.037	EPSD	ICGC	11.681	Loss
CAMK_MAPKAPK_MK2_MAPKAPK2_ST	Q96J92	WNK4	P49137	MAPKAPK2	S728	E723K	723	Missense	distal	-5	no	11.762	11.154	EPSD	ICGC;COSMIC;GDSC	11.681	Loss
CAMK_MAPKAPK_MK2_MAPKAPK2_ST	Q96J92	WNK4	P49137	MAPKAPK2	S1035	G1040C	1040	Missense	distal	5	no	12.136	12.091	EPSD	ICGC	11.681	Down-regulation
CAMK_MAPKAPK_MK2_MAPKAPK2_ST	Q96J92	WNK4	P49137	MAPKAPK2	S1035	S1039C	1039	Missense	distal	4	no	12.136	11.959	EPSD	ICGC;COSMIC	11.681	Down-regulation
CAMK_MAPKAPK_MK2_MAPKAPK2_ST	Q96J92	WNK4	P49137	MAPKAPK2	S1053	P1047H	1047	Missense	distal	-6	no	14.462	14.538	EPSD	ICGC;COSMIC	11.681	Up-regulation
CAMK_MAPKAPK_MK2_MAPKAPK2_ST	Q96J92	WNK4	P49137	MAPKAPK2	S1190	R1188H	1188	Missense	proximal	-2	no	17.327	14.896	EPSD	ICGC;COSMIC	11.681	Down-regulation
CAMK_MAPKAPK_MK2_MAPKAPK2_ST	Q96J92	WNK4	P49137	MAPKAPK2	S1190	R1187H	1187	Missense	distal	-3	no	17.327	12.568	EPSD	ICGC;COSMIC	11.681	Down-regulation
CAMK_MAPKAPK_MK2_MAPKAPK2_ST	Q96J92	WNK4	P49137	MAPKAPK2	S1190	S1197F	1197	Missense	distal	7	no	17.327	16.748	EPSD	ICGC	11.681	Down-regulation
CAMK_MAPKAPK_MK2_MAPKAPK2_ST	Q96J92	WNK4	P49137	MAPKAPK2	S1201	R1204H	1204	Missense	distal	3	no	17.888	17.751	EPSD	ICGC	11.681	Down-regulation
CAMK_MAPKAPK_MK2_MAPKAPK2_ST	Q96J92	WNK4	P49137	MAPKAPK2	S1201	S1197F	1197	Missense	distal	-4	no	17.888	18.283	EPSD	ICGC	11.681	Up-regulation
CAMK_MAPKAPK_MK2_MAPKAPK2_ST	Q96J92	WNK4	P49137	MAPKAPK2	S1217	G1211V	1211	Missense	distal	-6	no	17.773	17.733	EPSD	ICGC	11.681	Down-regulation
CAMK_MAPKAPK_MK2_MAPKAPK2_ST	Q96J92	WNK4	P49137	MAPKAPK2	S1217	T1223S	1223	Missense	distal	6	no	17.773	17.775	EPSD	ICGC;COSMIC	11.681	Up-regulation
CAMK_MAPKAPK_MK2_MAPKAPK2_ST	Q96J92	WNK4	P49137	MAPKAPK2	S1217	G1224D	1224	Missense	distal	7	no	17.773	17.866	EPSD	ICGC	11.681	Up-regulation
CAMK_MAPKAPK_MK2_MAPKAPK2_ST	Q96J92	WNK4	P49137	MAPKAPK2	S1219	Q1226H	1226	Missense	distal	7	no	12.359	12.257	EPSD	ICGC	11.681	Down-regulation
CAMK_MAPKAPK_MK2_MAPKAPK2_ST	Q96J92	WNK4	P49137	MAPKAPK2	S1219	T1223S	1223	Missense	distal	4	no	12.359	12.310	EPSD	ICGC;COSMIC	11.681	Down-regulation
CAMK_MAPKAPK_MK2_MAPKAPK2_ST	Q96J92	WNK4	P49137	MAPKAPK2	S1219	G1224D	1224	Missense	distal	5	no	12.359	12.342	EPSD	ICGC	11.681	Down-regulation
CAMK_MAPKAPK_MK2_MAPKAPK2_ST	Q96J92	WNK4	P49137	MAPKAPK2	S1221	Q1226H	1226	Missense	distal	5	no	12.687	12.774	EPSD	ICGC	11.681	Up-regulation
CAMK_MAPKAPK_MK2_MAPKAPK2_ST	Q96J92	WNK4	P49137	MAPKAPK2	S1221	T1223S	1223	Missense	proximal	2	no	12.687	12.663	EPSD	ICGC;COSMIC	11.681	Down-regulation
CAMK_MAPKAPK_MK2_MAPKAPK2_ST	Q96J92	WNK4	P49137	MAPKAPK2	S1221	G1224D	1224	Missense	distal	3	no	12.687	12.677	EPSD	ICGC	11.681	Down-regulation
CAMK_MAPKAPK_MK2_MAPKAPK2_ST	P16220	CREB1	P49137	MAPKAPK2	S133	D140A	140	Missense	distal	7	no	17.252	17.565	PhosphoSitePlus	ICGC;COSMIC	11.681	Up-regulation
CAMK_MAPKAPK_MK2_MAPKAPK2_ST	P16220	CREB1	P49137	MAPKAPK2	S142	D140A	140	Missense	proximal	-2	no	9.520	12.285	EPSD	ICGC;COSMIC	11.681	Gain
CAMK_MAPKAPK_MK2_MAPKAPK2_ST	Q6JBY9	RCSD1	P49137	MAPKAPK2	S17	Q22H	22	Missense	distal	5	no	15.435	15.522	EPSD	ICGC	11.681	Up-regulation
CAMK_MAPKAPK_MK2_MAPKAPK2_ST	Q6JBY9	RCSD1	P49137	MAPKAPK2	S17	A21D	21	Missense	distal	4	no	15.435	15.218	EPSD	ICGC;COSMIC	11.681	Down-regulation
CAMK_MAPKAPK_MK2_MAPKAPK2_ST	Q6JBY9	RCSD1	P49137	MAPKAPK2	S50	F54L	54	Missense	distal	4	no	12.794	12.953	EPSD	ICGC;COSMIC	11.681	Up-regulation
CAMK_MAPKAPK_MK2_MAPKAPK2_ST	Q6JBY9	RCSD1	P49137	MAPKAPK2	S50	P56H	56	Missense	distal	6	no	12.794	12.777	EPSD	ICGC;COSMIC;GDSC	11.681	Down-regulation
CAMK_MAPKAPK_MK2_MAPKAPK2_ST	Q6JBY9	RCSD1	P49137	MAPKAPK2	S50	L51P	51	Missense	proximal	1	no	12.794	12.703	EPSD	ICGC;COSMIC	11.681	Down-regulation
CAMK_MAPKAPK_MK2_MAPKAPK2_ST	Q6JBY9	RCSD1	P49137	MAPKAPK2	S50	P52L	52	Missense	proximal	2	no	12.794	12.571	EPSD	ICGC	11.681	Down-regulation
CAMK_MAPKAPK_MK2_MAPKAPK2_ST	Q6JBY9	RCSD1	P49137	MAPKAPK2	S171	P170L	170	Missense	proximal	-1	no	15.142	15.141	EPSD	ICGC	11.681	Down-regulation
CAMK_MAPKAPK_MK2_MAPKAPK2_ST	Q6JBY9	RCSD1	P49137	MAPKAPK2	S171	R175Q	175	Missense	distal	4	no	15.142	15.006	EPSD	ICGC;COSMIC	11.681	Down-regulation
CAMK_MAPKAPK_MK2_MAPKAPK2_ST	Q6JBY9	RCSD1	P49137	MAPKAPK2	S179	R175Q	175	Missense	distal	-4	no	19.154	19.343	PhosphoSitePlus;EPSD	ICGC;COSMIC	11.681	Up-regulation
CAMK_MAPKAPK_MK2_MAPKAPK2_ST	Q6JBY9	RCSD1	P49137	MAPKAPK2	S211	K212E	212	Missense	proximal	1	no	13.244	13.709	EPSD	ICGC;COSMIC	11.681	Up-regulation
CAMK_MAPKAPK_MK2_MAPKAPK2_ST	Q6JBY9	RCSD1	P49137	MAPKAPK2	S211	P208S	208	Missense	distal	-3	no	13.244	11.579	EPSD	ICGC	11.681	Loss
CAMK_MAPKAPK_MK2_MAPKAPK2_ST	Q6JBY9	RCSD1	P49137	MAPKAPK2	S242	T246A	246	Missense	distal	4	no	11.822	11.796	EPSD	ICGC;COSMIC	11.681	Down-regulation
CAMK_MAPKAPK_MK2_MAPKAPK2_ST	Q6JBY9	RCSD1	P49137	MAPKAPK2	S244	E250K	250	Missense	distal	6	no	19.793	19.779	EPSD;PhosphoSitePlus	ICGC;COSMIC	11.681	Down-regulation
CAMK_MAPKAPK_MK2_MAPKAPK2_ST	Q6JBY9	RCSD1	P49137	MAPKAPK2	S244	T246A	246	Missense	proximal	2	no	19.793	19.741	EPSD;PhosphoSitePlus	ICGC;COSMIC	11.681	Down-regulation
CAMK_MAPKAPK_MK2_MAPKAPK2_ST	Q6JBY9	RCSD1	P49137	MAPKAPK2	S268	R266W	266	Missense	proximal	-2	no	16.196	14.446	EPSD	ICGC	11.681	Down-regulation
CAMK_MAPKAPK_MK2_MAPKAPK2_ST	Q6JBY9	RCSD1	P49137	MAPKAPK2	S394	P400T	400	Missense	distal	6	no	12.750	12.764	EPSD	ICGC;COSMIC	11.681	Up-regulation
CAMK_MAPKAPK_MK2_MAPKAPK2_ST	P63104	YWHAZ	P49137	MAPKAPK2	S57	A54P	54	Missense	distal	-3	no	8.275	12.831	EPSD	ICGC;COSMIC	11.681	Gain
CAMK_MAPKAPK_MK2_MAPKAPK2_ST	P63104	YWHAZ	P49137	MAPKAPK2	S58	A54P	54	Missense	distal	-4	no	17.304	17.247	PhosphoSitePlus	ICGC;COSMIC	11.681	Down-regulation
CAMK_MAPKAPK_MK2_MAPKAPK2_ST	P63104	YWHAZ	P49137	MAPKAPK2	S110	N108S	108	Missense	proximal	-2	no	10.983	13.348	EPSD	ICGC;COSMIC	11.681	Gain
CAMK_MAPKAPK_MK2_MAPKAPK2_ST	Q9UKV8	AGO2	P49137	MAPKAPK2	S153	S148L	148	Missense	distal	-5	no	15.685	16.180	EPSD	ICGC;COSMIC	11.681	Up-regulation
CAMK_MAPKAPK_MK2_MAPKAPK2_ST	Q9UKV8	AGO2	P49137	MAPKAPK2	S153	T158K	158	Missense	distal	5	no	15.685	16.033	EPSD	ICGC	11.681	Up-regulation
CAMK_MAPKAPK_MK2_MAPKAPK2_ST	O95816	BAG2	P49137	MAPKAPK2	S20	D23E	23	Missense	distal	3	no	18.718	18.812	PhosphoSitePlus	ICGC;COSMIC	11.681	Up-regulation
CAMK_MAPKAPK_MK2_MAPKAPK2_ST	O95816	BAG2	P49137	MAPKAPK2	S20	A22T	22	Missense	proximal	2	no	18.718	18.771	PhosphoSitePlus	ICGC;COSMIC	11.681	Up-regulation
CAMK_MAPKAPK_MK2_MAPKAPK2_ST	O95816	BAG2	P49137	MAPKAPK2	S20	M21I	21	Missense	proximal	1	no	18.718	18.986	PhosphoSitePlus	ICGC;COSMIC	11.681	Up-regulation
CAMK_MAPKAPK_MK2_MAPKAPK2_ST	O95816	BAG2	P49137	MAPKAPK2	S73	R77T	77	Missense	distal	4	no	13.310	13.422	EPSD	ICGC;COSMIC	11.681	Up-regulation
CAMK_MAPKAPK_MK2_MAPKAPK2_ST	O95816	BAG2	P49137	MAPKAPK2	S73	G75V	75	Missense	proximal	2	no	13.310	13.410	EPSD	ICGC;COSMIC	11.681	Up-regulation
CAMK_MAPKAPK_MK2_MAPKAPK2_ST	Q00987	MDM2	P49137	MAPKAPK2	S40	K45N	45	Missense	distal	5	no	12.898	12.832	EPSD	ICGC	11.681	Down-regulation
CAMK_MAPKAPK_MK2_MAPKAPK2_ST	Q00987	MDM2	P49137	MAPKAPK2	S40	K45R	45	Missense	distal	5	no	12.898	12.611	EPSD	ICGC	11.681	Down-regulation
CAMK_MAPKAPK_MK2_MAPKAPK2_ST	Q00987	MDM2	P49137	MAPKAPK2	S40	K36R	36	Missense	distal	-4	no	12.898	12.654	EPSD	ICGC;COSMIC	11.681	Down-regulation
CAMK_MAPKAPK_MK2_MAPKAPK2_ST	Q00987	MDM2	P49137	MAPKAPK2	S186	S190C	190	Missense	distal	4	no	14.192	14.015	EPSD	ICGC;COSMIC	11.681	Down-regulation
CAMK_MAPKAPK_MK2_MAPKAPK2_ST	Q00987	MDM2	P49137	MAPKAPK2	S188	S190C	190	Missense	proximal	2	no	14.269	13.869	EPSD	ICGC;COSMIC	11.681	Down-regulation
CAMK_MAPKAPK_MK2_MAPKAPK2_ST	Q00987	MDM2	P49137	MAPKAPK2	S262	E267K	267	Missense	distal	5	no	12.611	12.824	EPSD	ICGC;COSMIC	11.681	Up-regulation
CAMK_MAPKAPK_MK2_MAPKAPK2_ST	Q9Y580	RBM7	P49137	MAPKAPK2	S88	A91V	91	Missense	distal	3	no	15.964	15.859	EPSD	ICGC;COSMIC	11.681	Down-regulation
CAMK_MAPKAPK_MK2_MAPKAPK2_ST	Q9Y580	RBM7	P49137	MAPKAPK2	S88	V95F	95	Missense	distal	7	no	15.964	15.608	EPSD	ICGC	11.681	Down-regulation
CAMK_MAPKAPK_MK2_MAPKAPK2_ST	Q9Y580	RBM7	P49137	MAPKAPK2	S113	T112A	112	Missense	proximal	-1	no	13.214	13.222	EPSD	ICGC;COSMIC	11.681	Up-regulation
CAMK_MAPKAPK_MK2_MAPKAPK2_ST	Q9Y580	RBM7	P49137	MAPKAPK2	S115	T112A	112	Missense	distal	-3	no	11.996	8.651	EPSD	ICGC;COSMIC	11.681	Loss
CAMK_MAPKAPK_MK2_MAPKAPK2_ST	Q9Y580	RBM7	P49137	MAPKAPK2	S178	S185C	185	Missense	distal	7	no	13.579	13.354	EPSD	ICGC;COSMIC	11.681	Down-regulation
CAMK_MAPKAPK_MK2_MAPKAPK2_ST	Q9Y580	RBM7	P49137	MAPKAPK2	S180	S186L	186	Missense	distal	6	no	13.837	13.817	EPSD	ICGC;COSMIC	11.681	Down-regulation
CAMK_MAPKAPK_MK2_MAPKAPK2_ST	Q9Y580	RBM7	P49137	MAPKAPK2	S180	S185C	185	Missense	distal	5	no	13.837	14.082	EPSD	ICGC;COSMIC	11.681	Up-regulation
CAMK_MAPKAPK_MK2_MAPKAPK2_ST	Q9Y580	RBM7	P49137	MAPKAPK2	S186	S186L	186	Missense	central	0	yes	14.525	0.000	EPSD	ICGC;COSMIC	11.681	Loss
CAMK_MAPKAPK_MK2_MAPKAPK2_ST	Q9Y580	RBM7	P49137	MAPKAPK2	S186	S185C	185	Missense	proximal	-1	no	14.525	14.536	EPSD	ICGC;COSMIC	11.681	Up-regulation
CAMK_MAPKAPK_MK2_MAPKAPK2_ST	O00418	EEF2K	P49137	MAPKAPK2	S66	S71F	71	Missense	distal	5	no	12.392	12.781	EPSD	ICGC;COSMIC	11.681	Up-regulation
CAMK_MAPKAPK_MK2_MAPKAPK2_ST	O00418	EEF2K	P49137	MAPKAPK2	S66	S66R	66	Missense	central	0	yes	12.392	0.000	EPSD	ICGC	11.681	Loss
CAMK_MAPKAPK_MK2_MAPKAPK2_ST	O00418	EEF2K	P49137	MAPKAPK2	S71	P75A	75	Missense	distal	4	no	13.537	13.619	EPSD	ICGC;COSMIC	11.681	Up-regulation
CAMK_MAPKAPK_MK2_MAPKAPK2_ST	O00418	EEF2K	P49137	MAPKAPK2	S71	P75L	75	Missense	distal	4	no	13.537	13.444	EPSD	ICGC;COSMIC	11.681	Down-regulation
CAMK_MAPKAPK_MK2_MAPKAPK2_ST	O00418	EEF2K	P49137	MAPKAPK2	S71	S71F	71	Missense	central	0	yes	13.537	0.000	EPSD	ICGC;COSMIC	11.681	Loss
CAMK_MAPKAPK_MK2_MAPKAPK2_ST	O00418	EEF2K	P49137	MAPKAPK2	S71	S66R	66	Missense	distal	-5	no	13.537	13.690	EPSD	ICGC	11.681	Up-regulation
CAMK_MAPKAPK_MK2_MAPKAPK2_ST	O00418	EEF2K	P49137	MAPKAPK2	S72	P75A	75	Missense	distal	3	no	11.866	11.918	EPSD	ICGC;COSMIC	11.681	Up-regulation
CAMK_MAPKAPK_MK2_MAPKAPK2_ST	O00418	EEF2K	P49137	MAPKAPK2	S72	P75L	75	Missense	distal	3	no	11.866	11.757	EPSD	ICGC;COSMIC	11.681	Down-regulation
CAMK_MAPKAPK_MK2_MAPKAPK2_ST	O00418	EEF2K	P49137	MAPKAPK2	S72	S71F	71	Missense	proximal	-1	no	11.866	11.882	EPSD	ICGC;COSMIC	11.681	Up-regulation
CAMK_MAPKAPK_MK2_MAPKAPK2_ST	O00418	EEF2K	P49137	MAPKAPK2	S72	F79L	79	Missense	distal	7	no	11.866	12.089	EPSD	ICGC	11.681	Up-regulation
CAMK_MAPKAPK_MK2_MAPKAPK2_ST	O00418	EEF2K	P49137	MAPKAPK2	S72	S66R	66	Missense	distal	-6	no	11.866	11.879	EPSD	ICGC	11.681	Up-regulation
CAMK_MAPKAPK_MK2_MAPKAPK2_ST	O00418	EEF2K	P49137	MAPKAPK2	S78	P75A	75	Missense	distal	-3	no	11.838	7.282	EPSD	ICGC;COSMIC	11.681	Loss
CAMK_MAPKAPK_MK2_MAPKAPK2_ST	O00418	EEF2K	P49137	MAPKAPK2	S78	P75L	75	Missense	distal	-3	no	11.838	11.412	EPSD	ICGC;COSMIC	11.681	Loss
CAMK_MAPKAPK_MK2_MAPKAPK2_ST	O00418	EEF2K	P49137	MAPKAPK2	S78	S71F	71	Missense	distal	-7	no	11.838	11.928	EPSD	ICGC;COSMIC	11.681	Up-regulation
CAMK_MAPKAPK_MK2_MAPKAPK2_ST	O00418	EEF2K	P49137	MAPKAPK2	S78	F79L	79	Missense	proximal	1	no	11.838	12.282	EPSD	ICGC	11.681	Up-regulation
CAMK_MAPKAPK_MK2_MAPKAPK2_ST	O00418	EEF2K	P49137	MAPKAPK2	S366	R369W	369	Missense	distal	3	no	16.411	16.373	EPSD	ICGC	11.681	Down-regulation
CAMK_MAPKAPK_MK2_MAPKAPK2_ST	O00418	EEF2K	P49137	MAPKAPK2	S366	Q361R	361	Missense	distal	-5	no	16.411	17.129	EPSD	ICGC	11.681	Up-regulation
CAMK_MAPKAPK_MK2_MAPKAPK2_ST	O00418	EEF2K	P49137	MAPKAPK2	S366	P360L	360	Missense	distal	-6	no	16.411	16.443	EPSD	ICGC	11.681	Up-regulation
CAMK_MAPKAPK_MK2_MAPKAPK2_ST	O00418	EEF2K	P49137	MAPKAPK2	S368	R369W	369	Missense	proximal	1	no	14.738	14.610	EPSD	ICGC	11.681	Down-regulation
CAMK_MAPKAPK_MK2_MAPKAPK2_ST	O00418	EEF2K	P49137	MAPKAPK2	S368	Q361R	361	Missense	distal	-7	no	14.738	14.651	EPSD	ICGC	11.681	Down-regulation
CAMK_MAPKAPK_MK2_MAPKAPK2_ST	O00418	EEF2K	P49137	MAPKAPK2	S398	S404C	404	Missense	distal	6	no	12.900	12.872	EPSD	ICGC	11.681	Down-regulation
CAMK_MAPKAPK_MK2_MAPKAPK2_ST	O00418	EEF2K	P49137	MAPKAPK2	S462	R466W	466	Missense	distal	4	no	12.213	12.103	EPSD	ICGC;COSMIC	11.681	Down-regulation
CAMK_MAPKAPK_MK2_MAPKAPK2_ST	O00418	EEF2K	P49137	MAPKAPK2	S462	R457L	457	Missense	distal	-5	no	12.213	12.554	EPSD	ICGC	11.681	Up-regulation
CAMK_MAPKAPK_MK2_MAPKAPK2_ST	O00418	EEF2K	P49137	MAPKAPK2	S464	R466W	466	Missense	proximal	2	no	12.912	12.601	EPSD	ICGC;COSMIC	11.681	Down-regulation
CAMK_MAPKAPK_MK2_MAPKAPK2_ST	O00418	EEF2K	P49137	MAPKAPK2	S464	D471Y	471	Missense	distal	7	no	12.912	12.529	EPSD	ICGC	11.681	Down-regulation
CAMK_MAPKAPK_MK2_MAPKAPK2_ST	O00418	EEF2K	P49137	MAPKAPK2	S464	R457L	457	Missense	distal	-7	no	12.912	12.978	EPSD	ICGC	11.681	Up-regulation
CAMK_MAPKAPK_MK2_MAPKAPK2_ST	P07101	TH	P49137	MAPKAPK2	S19	E20Q	20	Missense	proximal	1	no	19.504	18.991	EPSD;PhosphoSitePlus	ICGC;COSMIC	11.681	Down-regulation
CAMK_MAPKAPK_MK2_MAPKAPK2_ST	P07101	TH	P49137	MAPKAPK2	S19	K12R	12	Missense	distal	-7	no	19.504	19.429	EPSD;PhosphoSitePlus	ICGC;COSMIC	11.681	Down-regulation
CAMK_MAPKAPK_MK2_MAPKAPK2_ST	P05783	KRT18	P49137	MAPKAPK2	S30	A32S	32	Missense	proximal	2	no	16.484	16.513	EPSD	ICGC;COSMIC	11.681	Up-regulation
CAMK_MAPKAPK_MK2_MAPKAPK2_ST	P05783	KRT18	P49137	MAPKAPK2	S30	A26T	26	Missense	distal	-4	no	16.484	16.359	EPSD	ICGC;COSMIC	11.681	Down-regulation
CAMK_MAPKAPK_MK2_MAPKAPK2_ST	P05783	KRT18	P49137	MAPKAPK2	S30	S34R	34	Missense	distal	4	no	16.484	16.420	EPSD	ICGC;COSMIC	11.681	Down-regulation
CAMK_MAPKAPK_MK2_MAPKAPK2_ST	P05783	KRT18	P49137	MAPKAPK2	S30	P28Q	28	Missense	proximal	-2	no	16.484	17.456	EPSD	ICGC;COSMIC	11.681	Up-regulation
CAMK_MAPKAPK_MK2_MAPKAPK2_ST	P05783	KRT18	P49137	MAPKAPK2	S30	R27W	27	Missense	distal	-3	no	16.484	7.905	EPSD	ICGC;COSMIC	11.681	Loss
CAMK_MAPKAPK_MK2_MAPKAPK2_ST	P05783	KRT18	P49137	MAPKAPK2	S30	G25C	25	Missense	distal	-5	no	16.484	16.912	EPSD	ICGC;COSMIC	11.681	Up-regulation
CAMK_MAPKAPK_MK2_MAPKAPK2_ST	P05783	KRT18	P49137	MAPKAPK2	S30	A37T	37	Missense	distal	7	no	16.484	16.586	EPSD	ICGC;COSMIC	11.681	Up-regulation
CAMK_MAPKAPK_MK2_MAPKAPK2_ST	P05783	KRT18	P49137	MAPKAPK2	S34	A32S	32	Missense	proximal	-2	no	11.834	13.429	EPSD	ICGC;COSMIC	11.681	Up-regulation
CAMK_MAPKAPK_MK2_MAPKAPK2_ST	P05783	KRT18	P49137	MAPKAPK2	S34	G38C	38	Missense	distal	4	no	11.834	11.846	EPSD	ICGC	11.681	Up-regulation
CAMK_MAPKAPK_MK2_MAPKAPK2_ST	P05783	KRT18	P49137	MAPKAPK2	S34	S34R	34	Missense	central	0	yes	11.834	0.000	EPSD	ICGC;COSMIC	11.681	Loss
CAMK_MAPKAPK_MK2_MAPKAPK2_ST	P05783	KRT18	P49137	MAPKAPK2	S34	P28Q	28	Missense	distal	-6	no	11.834	11.900	EPSD	ICGC;COSMIC	11.681	Up-regulation
CAMK_MAPKAPK_MK2_MAPKAPK2_ST	P05783	KRT18	P49137	MAPKAPK2	S34	R27W	27	Missense	distal	-7	no	11.834	11.912	EPSD	ICGC;COSMIC	11.681	Up-regulation
CAMK_MAPKAPK_MK2_MAPKAPK2_ST	P05783	KRT18	P49137	MAPKAPK2	S34	A37T	37	Missense	distal	3	no	11.834	11.862	EPSD	ICGC;COSMIC	11.681	Up-regulation
CAMK_MAPKAPK_MK2_MAPKAPK2_ST	P05783	KRT18	P49137	MAPKAPK2	S49	R45P	45	Missense	distal	-4	no	14.733	14.801	EPSD	ICGC;COSMIC	11.681	Up-regulation
CAMK_MAPKAPK_MK2_MAPKAPK2_ST	P05783	KRT18	P49137	MAPKAPK2	S49	V48M	48	Missense	proximal	-1	no	14.733	14.738	EPSD	ICGC;COSMIC	11.681	Up-regulation
CAMK_MAPKAPK_MK2_MAPKAPK2_ST	P05783	KRT18	P49137	MAPKAPK2	S49	R50C	50	Missense	proximal	1	no	14.733	14.471	EPSD	ICGC;COSMIC	11.681	Down-regulation
CAMK_MAPKAPK_MK2_MAPKAPK2_ST	P05783	KRT18	P49137	MAPKAPK2	S49	G56D	56	Missense	distal	7	no	14.733	14.826	EPSD	ICGC;COSMIC	11.681	Up-regulation
CAMK_MAPKAPK_MK2_MAPKAPK2_ST	P05783	KRT18	P49137	MAPKAPK2	S49	G43R	43	Missense	distal	-6	no	14.733	14.661	EPSD	ICGC	11.681	Down-regulation
CAMK_MAPKAPK_MK2_MAPKAPK2_ST	P05783	KRT18	P49137	MAPKAPK2	S49	I46T	46	Missense	distal	-3	no	14.733	14.146	EPSD	ICGC;COSMIC	11.681	Down-regulation
CAMK_MAPKAPK_MK2_MAPKAPK2_ST	P05783	KRT18	P49137	MAPKAPK2	S51	R45P	45	Missense	distal	-6	no	13.030	13.018	EPSD	ICGC;COSMIC	11.681	Down-regulation
CAMK_MAPKAPK_MK2_MAPKAPK2_ST	P05783	KRT18	P49137	MAPKAPK2	S51	V48M	48	Missense	distal	-3	no	13.030	12.368	EPSD	ICGC;COSMIC	11.681	Down-regulation
CAMK_MAPKAPK_MK2_MAPKAPK2_ST	P05783	KRT18	P49137	MAPKAPK2	S51	R50C	50	Missense	proximal	-1	no	13.030	13.051	EPSD	ICGC;COSMIC	11.681	Up-regulation
CAMK_MAPKAPK_MK2_MAPKAPK2_ST	P05783	KRT18	P49137	MAPKAPK2	S51	G56D	56	Missense	distal	5	no	13.030	13.014	EPSD	ICGC;COSMIC	11.681	Down-regulation
CAMK_MAPKAPK_MK2_MAPKAPK2_ST	P05783	KRT18	P49137	MAPKAPK2	S51	I46T	46	Missense	distal	-5	no	13.030	12.643	EPSD	ICGC;COSMIC	11.681	Down-regulation
CAMK_MAPKAPK_MK2_MAPKAPK2_ST	P05783	KRT18	P49137	MAPKAPK2	S53	V48M	48	Missense	distal	-5	no	19.256	18.807	PhosphoSitePlus	ICGC;COSMIC	11.681	Down-regulation
CAMK_MAPKAPK_MK2_MAPKAPK2_ST	P05783	KRT18	P49137	MAPKAPK2	S53	R50C	50	Missense	distal	-3	no	19.256	10.856	PhosphoSitePlus	ICGC;COSMIC	11.681	Loss
CAMK_MAPKAPK_MK2_MAPKAPK2_ST	P05783	KRT18	P49137	MAPKAPK2	S53	G56D	56	Missense	distal	3	no	19.256	19.246	PhosphoSitePlus	ICGC;COSMIC	11.681	Down-regulation
CAMK_MAPKAPK_MK2_MAPKAPK2_ST	P05783	KRT18	P49137	MAPKAPK2	S53	G59W	59	Missense	distal	6	no	19.256	19.258	PhosphoSitePlus	ICGC;COSMIC	11.681	Up-regulation
CAMK_MAPKAPK_MK2_MAPKAPK2_ST	P05783	KRT18	P49137	MAPKAPK2	S53	I46T	46	Missense	distal	-7	no	19.256	19.194	PhosphoSitePlus	ICGC;COSMIC	11.681	Down-regulation
CAMK_MAPKAPK_MK2_MAPKAPK2_ST	P05783	KRT18	P49137	MAPKAPK2	S93	D89N	89	Missense	distal	-4	no	13.121	13.083	EPSD	ICGC;COSMIC	11.681	Down-regulation
CAMK_MAPKAPK_MK2_MAPKAPK2_ST	P05783	KRT18	P49137	MAPKAPK2	S93	A92P	92	Missense	proximal	-1	no	13.121	13.118	EPSD	ICGC;COSMIC	11.681	Down-regulation
CAMK_MAPKAPK_MK2_MAPKAPK2_ST	P05783	KRT18	P49137	MAPKAPK2	S93	S86N	86	Missense	distal	-7	no	13.121	13.171	EPSD	ICGC;COSMIC	11.681	Up-regulation
CAMK_MAPKAPK_MK2_MAPKAPK2_ST	P05783	KRT18	P49137	MAPKAPK2	S100	R106L	106	Missense	distal	6	no	16.165	16.148	EPSD	ICGC;COSMIC	11.681	Down-regulation
CAMK_MAPKAPK_MK2_MAPKAPK2_ST	P05783	KRT18	P49137	MAPKAPK2	S100	R107K	107	Missense	distal	7	no	16.165	15.942	EPSD	ICGC;COSMIC	11.681	Down-regulation
CAMK_MAPKAPK_MK2_MAPKAPK2_ST	P05783	KRT18	P49137	MAPKAPK2	S100	R106W	106	Missense	distal	6	no	16.165	16.140	EPSD	ICGC;COSMIC	11.681	Down-regulation
CAMK_MAPKAPK_MK2_MAPKAPK2_ST	P05783	KRT18	P49137	MAPKAPK2	S100	T103N	103	Missense	distal	3	no	16.165	15.935	EPSD	ICGC;COSMIC	11.681	Down-regulation
CAMK_MAPKAPK_MK2_MAPKAPK2_ST	P05783	KRT18	P49137	MAPKAPK2	S100	E102D	102	Missense	proximal	2	no	16.165	15.921	EPSD	ICGC;COSMIC	11.681	Down-regulation
CAMK_MAPKAPK_MK2_MAPKAPK2_ST	P05783	KRT18	P49137	MAPKAPK2	S110	R106L	106	Missense	distal	-4	no	14.121	14.314	EPSD	ICGC;COSMIC	11.681	Up-regulation
CAMK_MAPKAPK_MK2_MAPKAPK2_ST	P05783	KRT18	P49137	MAPKAPK2	S110	R107K	107	Missense	distal	-3	no	14.121	8.997	EPSD	ICGC;COSMIC	11.681	Loss
CAMK_MAPKAPK_MK2_MAPKAPK2_ST	P05783	KRT18	P49137	MAPKAPK2	S110	R106W	106	Missense	distal	-4	no	14.121	14.339	EPSD	ICGC;COSMIC	11.681	Up-regulation
CAMK_MAPKAPK_MK2_MAPKAPK2_ST	P05783	KRT18	P49137	MAPKAPK2	S110	T103N	103	Missense	distal	-7	no	14.121	14.201	EPSD	ICGC;COSMIC	11.681	Up-regulation
CAMK_MAPKAPK_MK2_MAPKAPK2_ST	P05783	KRT18	P49137	MAPKAPK2	S110	E109D	109	Missense	proximal	-1	no	14.121	14.133	EPSD	ICGC;COSMIC	11.681	Up-regulation
CAMK_MAPKAPK_MK2_MAPKAPK2_ST	P05783	KRT18	P49137	MAPKAPK2	S110	R113L	113	Missense	distal	3	no	14.121	14.074	EPSD	ICGC;COSMIC	11.681	Down-regulation
CAMK_MAPKAPK_MK2_MAPKAPK2_ST	P05783	KRT18	P49137	MAPKAPK2	S127	K131T	131	Missense	distal	4	no	12.738	13.026	EPSD	ICGC;COSMIC	11.681	Up-regulation
CAMK_MAPKAPK_MK2_MAPKAPK2_ST	P05783	KRT18	P49137	MAPKAPK2	S127	Q122P	122	Missense	distal	-5	no	12.738	13.292	EPSD	ICGC;COSMIC	11.681	Up-regulation
CAMK_MAPKAPK_MK2_MAPKAPK2_ST	P05783	KRT18	P49137	MAPKAPK2	S127	V123D	123	Missense	distal	-4	no	12.738	12.782	EPSD	ICGC;COSMIC	11.681	Up-regulation
CAMK_MAPKAPK_MK2_MAPKAPK2_ST	P05783	KRT18	P49137	MAPKAPK2	S127	P121H	121	Missense	distal	-6	no	12.738	12.814	EPSD	ICGC;COSMIC	11.681	Up-regulation
CAMK_MAPKAPK_MK2_MAPKAPK2_ST	P18615	NELFE	P49137	MAPKAPK2	S251	R247Q	247	Missense	distal	-4	no	19.741	19.931	EPSD;PhosphoSitePlus	ICGC;COSMIC	11.681	Up-regulation
CAMK_MAPKAPK_MK2_MAPKAPK2_ST	P49137	MAPKAPK2	P49137	MAPKAPK2	S328	P332H	332	Missense	distal	4	no	12.202	11.958	EPSD	ICGC;COSMIC	11.681	Down-regulation
CAMK_MAPKAPK_MK2_MAPKAPK2_ST	Q07352	ZFP36L1	P49137	MAPKAPK2	S54	P50S	50	Missense	distal	-4	no	16.902	16.822	EPSD;PhosphoSitePlus	ICGC;COSMIC	11.681	Down-regulation
CAMK_MAPKAPK_MK2_MAPKAPK2_ST	Q07352	ZFP36L1	P49137	MAPKAPK2	S80	P75S	75	Missense	distal	-5	no	11.677	11.688	EPSD	ICGC	11.681	Gain
CAMK_MAPKAPK_MK2_MAPKAPK2_ST	Q07352	ZFP36L1	P49137	MAPKAPK2	S80	S81L	81	Missense	proximal	1	no	11.677	11.879	EPSD	ICGC;COSMIC	11.681	Gain
CAMK_MAPKAPK_MK2_MAPKAPK2_ST	Q07352	ZFP36L1	P49137	MAPKAPK2	S84	S81L	81	Missense	distal	-3	no	10.888	12.127	EPSD	ICGC;COSMIC	11.681	Gain
CAMK_MAPKAPK_MK2_MAPKAPK2_ST	Q07352	ZFP36L1	P49137	MAPKAPK2	T148	T155K	155	Missense	distal	7	no	14.848	14.351	EPSD	ICGC	11.681	Down-regulation
CAMK_MAPKAPK_MK2_MAPKAPK2_ST	Q07352	ZFP36L1	P49137	MAPKAPK2	S192	R197C	197	Missense	distal	5	no	12.901	13.127	EPSD	ICGC;COSMIC	11.681	Up-regulation
CAMK_MAPKAPK_MK2_MAPKAPK2_ST	Q07352	ZFP36L1	P49137	MAPKAPK2	S192	A193T	193	Missense	proximal	1	no	12.901	13.107	EPSD	ICGC	11.681	Up-regulation
CAMK_MAPKAPK_MK2_MAPKAPK2_ST	Q07352	ZFP36L1	P49137	MAPKAPK2	S192	P196L	196	Missense	distal	4	no	12.901	12.808	EPSD	ICGC;COSMIC	11.681	Down-regulation
CAMK_MAPKAPK_MK2_MAPKAPK2_ST	Q07352	ZFP36L1	P49137	MAPKAPK2	S192	R189L	189	Missense	distal	-3	no	12.901	7.811	EPSD	ICGC;COSMIC	11.681	Loss
CAMK_MAPKAPK_MK2_MAPKAPK2_ST	Q07352	ZFP36L1	P49137	MAPKAPK2	S201	R197C	197	Missense	distal	-4	no	12.685	12.913	EPSD	ICGC;COSMIC	11.681	Up-regulation
CAMK_MAPKAPK_MK2_MAPKAPK2_ST	Q07352	ZFP36L1	P49137	MAPKAPK2	S201	G206W	206	Missense	distal	5	no	12.685	12.633	EPSD	ICGC;COSMIC	11.681	Down-regulation
CAMK_MAPKAPK_MK2_MAPKAPK2_ST	Q07352	ZFP36L1	P49137	MAPKAPK2	S201	S203N	203	Missense	proximal	2	no	12.685	12.269	EPSD	ICGC	11.681	Down-regulation
CAMK_MAPKAPK_MK2_MAPKAPK2_ST	Q07352	ZFP36L1	P49137	MAPKAPK2	S201	P196L	196	Missense	distal	-5	no	12.685	13.190	EPSD	ICGC;COSMIC	11.681	Up-regulation
CAMK_MAPKAPK_MK2_MAPKAPK2_ST	Q07352	ZFP36L1	P49137	MAPKAPK2	S203	R197C	197	Missense	distal	-6	no	15.900	15.950	EPSD;PhosphoSitePlus	ICGC;COSMIC	11.681	Up-regulation
CAMK_MAPKAPK_MK2_MAPKAPK2_ST	Q07352	ZFP36L1	P49137	MAPKAPK2	S203	G206W	206	Missense	distal	3	no	15.900	15.893	EPSD;PhosphoSitePlus	ICGC;COSMIC	11.681	Down-regulation
CAMK_MAPKAPK_MK2_MAPKAPK2_ST	Q07352	ZFP36L1	P49137	MAPKAPK2	S203	S203N	203	Missense	central	0	yes	15.900	0.000	EPSD;PhosphoSitePlus	ICGC	11.681	Loss
CAMK_MAPKAPK_MK2_MAPKAPK2_ST	Q07352	ZFP36L1	P49137	MAPKAPK2	S203	P196L	196	Missense	distal	-7	no	15.900	15.935	EPSD;PhosphoSitePlus	ICGC;COSMIC	11.681	Up-regulation
CAMK_MAPKAPK_MK2_MAPKAPK2_ST	Q07352	ZFP36L1	P49137	MAPKAPK2	S336	S334F	334	Missense	proximal	-2	no	13.460	8.033	EPSD	ICGC;COSMIC	11.681	Loss
CAMK_MAPKAPK_MK2_MAPKAPK2_ST	Q9NQC3	RTN4	P49137	MAPKAPK2	S15	S13W	13	Missense	proximal	-2	no	12.823	8.806	EPSD	ICGC;COSMIC	11.681	Loss
CAMK_MAPKAPK_MK2_MAPKAPK2_ST	Q9NQC3	RTN4	P49137	MAPKAPK2	S15	S15N	15	Missense	central	0	yes	12.823	0.000	EPSD	ICGC	11.681	Loss
CAMK_MAPKAPK_MK2_MAPKAPK2_ST	Q9NQC3	RTN4	P49137	MAPKAPK2	S15	P8H	8	Missense	distal	-7	no	12.823	12.882	EPSD	ICGC;COSMIC	11.681	Up-regulation
CAMK_MAPKAPK_MK2_MAPKAPK2_ST	Q9NQC3	RTN4	P49137	MAPKAPK2	S107	R104Q	104	Missense	distal	-3	no	18.408	12.644	PhosphoSitePlus	ICGC	11.681	Down-regulation
CAMK_MAPKAPK_MK2_MAPKAPK2_ST	Q9NQC3	RTN4	P49137	MAPKAPK2	S121	A126P	126	Missense	distal	5	no	12.200	12.243	EPSD	ICGC;COSMIC	11.681	Up-regulation
CAMK_MAPKAPK_MK2_MAPKAPK2_ST	Q9NQC3	RTN4	P49137	MAPKAPK2	S129	A126P	126	Missense	distal	-3	no	9.235	13.792	EPSD	ICGC;COSMIC	11.681	Gain
CAMK_MAPKAPK_MK2_MAPKAPK2_ST	Q9NQC3	RTN4	P49137	MAPKAPK2	S131	A126P	126	Missense	distal	-5	no	12.253	12.726	EPSD	ICGC;COSMIC	11.681	Up-regulation
CAMK_MAPKAPK_MK2_MAPKAPK2_ST	Q9NQC3	RTN4	P49137	MAPKAPK2	S150	P147A	147	Missense	distal	-3	no	11.742	7.186	EPSD	ICGC	11.681	Loss
CAMK_MAPKAPK_MK2_MAPKAPK2_ST	Q9NQC3	RTN4	P49137	MAPKAPK2	S150	S150R	150	Missense	central	0	yes	11.742	0.000	EPSD	ICGC;COSMIC	11.681	Loss
CAMK_MAPKAPK_MK2_MAPKAPK2_ST	Q9NQC3	RTN4	P49137	MAPKAPK2	S196	R201G	201	Missense	distal	5	no	14.712	14.983	EPSD	ICGC;COSMIC	11.681	Up-regulation
CAMK_MAPKAPK_MK2_MAPKAPK2_ST	Q9NQC3	RTN4	P49137	MAPKAPK2	S237	S234R	234	Missense	distal	-3	no	7.651	13.981	EPSD	ICGC;COSMIC	11.681	Gain
CAMK_MAPKAPK_MK2_MAPKAPK2_ST	Q9NQC3	RTN4	P49137	MAPKAPK2	S239	S234R	234	Missense	distal	-5	no	13.945	14.099	EPSD	ICGC;COSMIC	11.681	Up-regulation
CAMK_MAPKAPK_MK2_MAPKAPK2_ST	P53350	PLK1	P49137	MAPKAPK2	S137	E140Q	140	Missense	distal	3	no	16.932	16.784	EPSD	ICGC;COSMIC	11.681	Down-regulation
CAMK_MAPKAPK_MK2_MAPKAPK2_ST	P53350	PLK1	P49137	MAPKAPK2	S326	D333Y	333	Missense	distal	7	no	12.908	12.525	PhosphoSitePlus;EPSD	ICGC	11.681	Down-regulation
CAMK_MAPKAPK_MK2_MAPKAPK2_ST	P53350	PLK1	P49137	MAPKAPK2	S326	I327V	327	Missense	proximal	1	no	12.908	13.000	PhosphoSitePlus;EPSD	ICGC;COSMIC	11.681	Up-regulation
CAMK_MAPKAPK_MK2_MAPKAPK2_ST	P53350	PLK1	P49137	MAPKAPK2	S330	D333Y	333	Missense	distal	3	no	12.702	12.561	EPSD	ICGC	11.681	Down-regulation
CAMK_MAPKAPK_MK2_MAPKAPK2_ST	P53350	PLK1	P49137	MAPKAPK2	S330	I327V	327	Missense	distal	-3	no	12.702	10.262	EPSD	ICGC;COSMIC	11.681	Loss
CAMK_MAPKAPK_MK2_MAPKAPK2_ST	P53350	PLK1	P49137	MAPKAPK2	S383	Q380K	380	Missense	distal	-3	no	11.175	11.815	EPSD;PhosphoSitePlus	ICGC;COSMIC	11.681	Gain
CAMK_MAPKAPK_MK2_MAPKAPK2_ST	P53350	PLK1	P49137	MAPKAPK2	S565	R563H	563	Missense	proximal	-2	no	12.059	9.627	EPSD	ICGC;COSMIC	11.681	Loss
CAMK_MAPKAPK_MK2_MAPKAPK2_ST	P53350	PLK1	P49137	MAPKAPK2	S565	R563C	563	Missense	proximal	-2	no	12.059	10.847	EPSD	ICGC;COSMIC	11.681	Loss
CAMK_MAPKAPK_MK2_MAPKAPK2_ST	P53350	PLK1	P49137	MAPKAPK2	S565	R560C	560	Missense	distal	-5	no	12.059	11.454	EPSD	ICGC	11.681	Loss
CAMK_MAPKAPK_MK2_MAPKAPK2_ST	P53350	PLK1	P49137	MAPKAPK2	S565	S565I	565	Missense	central	0	yes	12.059	0.000	EPSD	ICGC;COSMIC	11.681	Loss
CAMK_MAPKAPK_MK2_MAPKAPK2_ST	P53350	PLK1	P49137	MAPKAPK2	S565	Y562D	562	Missense	distal	-3	no	12.059	10.681	EPSD	ICGC	11.681	Loss
CAMK_MAPKAPK_MK2_MAPKAPK2_ST	P53350	PLK1	P49137	MAPKAPK2	S592	R599C	599	Missense	distal	7	no	12.258	12.004	EPSD	ICGC;COSMIC	11.681	Down-regulation
CAMK_MAPKAPK_MK2_MAPKAPK2_ST	P53350	PLK1	P49137	MAPKAPK2	S592	A596V	596	Missense	distal	4	no	12.258	12.107	EPSD	ICGC;COSMIC	11.681	Down-regulation
CAMK_MAPKAPK_MK2_MAPKAPK2_ST	P53350	PLK1	P49137	MAPKAPK2	S592	R599L	599	Missense	distal	7	no	12.258	11.873	EPSD	ICGC	11.681	Down-regulation
CAMK_MAPKAPK_MK2_MAPKAPK2_ST	P53350	PLK1	P49137	MAPKAPK2	S592	S597N	597	Missense	distal	5	no	12.258	12.497	EPSD	ICGC;COSMIC	11.681	Up-regulation
CAMK_MAPKAPK_MK2_MAPKAPK2_ST	P53350	PLK1	P49137	MAPKAPK2	S597	R599C	599	Missense	proximal	2	no	18.136	17.841	EPSD	ICGC;COSMIC	11.681	Down-regulation
CAMK_MAPKAPK_MK2_MAPKAPK2_ST	P53350	PLK1	P49137	MAPKAPK2	S597	A596V	596	Missense	proximal	-1	no	18.136	18.135	EPSD	ICGC;COSMIC	11.681	Down-regulation
CAMK_MAPKAPK_MK2_MAPKAPK2_ST	P53350	PLK1	P49137	MAPKAPK2	S597	R599L	599	Missense	proximal	2	no	18.136	17.826	EPSD	ICGC	11.681	Down-regulation
CAMK_MAPKAPK_MK2_MAPKAPK2_ST	P53350	PLK1	P49137	MAPKAPK2	S597	S597N	597	Missense	central	0	yes	18.136	0.000	EPSD	ICGC;COSMIC	11.681	Loss
CAMK_MAPKAPK_MK2_MAPKAPK2_ST	P53350	PLK1	P49137	MAPKAPK2	S597	L600H	600	Missense	distal	3	no	18.136	18.046	EPSD	ICGC;COSMIC	11.681	Down-regulation
CAMK_MAPKAPK_MK2_MAPKAPK2_ST	P31749	AKT1	P49137	MAPKAPK2	S246	D248H	248	Missense	proximal	2	no	13.107	12.944	EPSD	ICGC;COSMIC	11.681	Down-regulation
CAMK_MAPKAPK_MK2_MAPKAPK2_ST	P31749	AKT1	P49137	MAPKAPK2	S246	A250D	250	Missense	distal	4	no	13.107	12.889	EPSD	ICGC	11.681	Down-regulation
CAMK_MAPKAPK_MK2_MAPKAPK2_ST	P31749	AKT1	P49137	MAPKAPK2	S246	E242K	242	Missense	distal	-4	no	13.107	13.274	EPSD	ICGC	11.681	Up-regulation
CAMK_MAPKAPK_MK2_MAPKAPK2_ST	P31749	AKT1	P49137	MAPKAPK2	S246	V244A	244	Missense	proximal	-2	no	13.107	15.307	EPSD	ICGC	11.681	Up-regulation
CAMK_MAPKAPK_MK2_MAPKAPK2_ST	P31749	AKT1	P49137	MAPKAPK2	S246	R249W	249	Missense	distal	3	no	13.107	13.069	EPSD	ICGC;COSMIC	11.681	Down-regulation
CAMK_MAPKAPK_MK2_MAPKAPK2_ST	P31749	AKT1	P49137	MAPKAPK2	S246	R251S	251	Missense	distal	5	no	13.107	13.088	EPSD	ICGC;COSMIC	11.681	Down-regulation
CAMK_MAPKAPK_MK2_MAPKAPK2_ST	P31749	AKT1	P49137	MAPKAPK2	S473	Q471K	471	Missense	proximal	-2	no	12.620	10.439	PhosphoSitePlus	ICGC	11.681	Loss
CAMK_MAPKAPK_MK2_MAPKAPK2_ST	P31749	AKT1	P49137	MAPKAPK2	S473	S477R	477	Missense	distal	4	no	12.620	12.556	PhosphoSitePlus	ICGC	11.681	Down-regulation
CAMK_MAPKAPK_MK2_MAPKAPK2_ST	P31749	AKT1	P49137	MAPKAPK2	S477	Q471K	471	Missense	distal	-6	no	12.069	12.071	EPSD	ICGC	11.681	Up-regulation
CAMK_MAPKAPK_MK2_MAPKAPK2_ST	P31749	AKT1	P49137	MAPKAPK2	S477	S477R	477	Missense	central	0	yes	12.069	0.000	EPSD	ICGC	11.681	Loss
CAMK_MAPKAPK_MK2_MAPKAPK2_ST	O15511	ARPC5	P49137	MAPKAPK2	S77	K72E	72	Missense	distal	-5	no	16.791	17.399	PhosphoSitePlus	ICGC;COSMIC	11.681	Up-regulation
CAMK_MAPKAPK_MK2_MAPKAPK2_ST	O15511	ARPC5	P49137	MAPKAPK2	S77	I84V	84	Missense	distal	7	no	16.791	16.831	PhosphoSitePlus	ICGC;COSMIC	11.681	Up-regulation
CAMK_MAPKAPK_MK2_MAPKAPK2_ST	O15511	ARPC5	P49137	MAPKAPK2	T146	R148I	148	Missense	proximal	2	no	11.823	11.510	EPSD	ICGC;COSMIC	11.681	Loss
CAMK_MAPKAPK_MK2_MAPKAPK2_ST	P04637	TP53	P49137	MAPKAPK2	S20	W23C	23	Missense	distal	3	no	12.451	12.439	PhosphoSitePlus	ICGC;COSMIC	11.681	Down-regulation
CAMK_MAPKAPK_MK2_MAPKAPK2_ST	P04637	TP53	P49137	MAPKAPK2	S127	C124R	124	Missense	distal	-3	no	8.447	16.846	EPSD	ICGC;COSMIC;GDSC;CCLE	11.681	Gain
CAMK_MAPKAPK_MK2_MAPKAPK2_ST	P04637	TP53	P49137	MAPKAPK2	T155	P152R	152	Missense	distal	-3	no	7.533	12.198	EPSD	ICGC;COSMIC	11.681	Gain
CAMK_MAPKAPK_MK2_MAPKAPK2_ST	P04637	TP53	P49137	MAPKAPK2	S183	C182W	182	Missense	proximal	-1	no	12.691	12.689	EPSD	ICGC;COSMIC	11.681	Down-regulation
CAMK_MAPKAPK_MK2_MAPKAPK2_ST	P04637	TP53	P49137	MAPKAPK2	S183	H178D	178	Missense	distal	-5	no	12.691	12.239	EPSD	ICGC;COSMIC;CCLE	11.681	Down-regulation
CAMK_MAPKAPK_MK2_MAPKAPK2_ST	P04637	TP53	P49137	MAPKAPK2	S183	D184H	184	Missense	proximal	1	no	12.691	12.677	EPSD	ICGC;COSMIC	11.681	Down-regulation
CAMK_MAPKAPK_MK2_MAPKAPK2_ST	P04637	TP53	P49137	MAPKAPK2	S183	A189T	189	Missense	distal	6	no	12.691	12.699	EPSD	ICGC;COSMIC	11.681	Up-regulation
CAMK_MAPKAPK_MK2_MAPKAPK2_ST	P04637	TP53	P49137	MAPKAPK2	S183	P190T	190	Missense	distal	7	no	12.691	12.877	EPSD	ICGC;COSMIC	11.681	Up-regulation
CAMK_MAPKAPK_MK2_MAPKAPK2_ST	P04637	TP53	P49137	MAPKAPK2	S183	P190S	190	Missense	distal	7	no	12.691	12.574	EPSD	ICGC;COSMIC	11.681	Down-regulation
CAMK_MAPKAPK_MK2_MAPKAPK2_ST	P04637	TP53	P49137	MAPKAPK2	S183	A189D	189	Missense	distal	6	no	12.691	12.670	EPSD	ICGC;COSMIC	11.681	Down-regulation
CAMK_MAPKAPK_MK2_MAPKAPK2_ST	P04637	TP53	P49137	MAPKAPK2	S183	E180D	180	Missense	distal	-3	no	12.691	10.868	EPSD	ICGC;COSMIC	11.681	Loss
CAMK_MAPKAPK_MK2_MAPKAPK2_ST	P04637	TP53	P49137	MAPKAPK2	S183	C176G	176	Missense	distal	-7	no	12.691	12.705	EPSD	ICGC;COSMIC	11.681	Up-regulation
CAMK_MAPKAPK_MK2_MAPKAPK2_ST	P04637	TP53	P49137	MAPKAPK2	S314	T312I	312	Missense	proximal	-2	no	12.556	9.968	EPSD	ICGC;COSMIC	11.681	Loss
CAMK_MAPKAPK_MK2_MAPKAPK2_ST	P04637	TP53	P49137	MAPKAPK2	S315	T312I	312	Missense	distal	-3	no	12.896	13.482	EPSD	ICGC;COSMIC	11.681	Up-regulation
CAMK_MAPKAPK_MK2_MAPKAPK2_ST	P04637	TP53	P49137	MAPKAPK2	S315	P322T	322	Missense	distal	7	no	12.896	13.081	EPSD	ICGC	11.681	Up-regulation
CAMK_MAPKAPK_MK2_MAPKAPK2_ST	P04637	TP53	P49137	MAPKAPK2	S378	T377P	377	Missense	proximal	-1	no	13.171	13.176	EPSD	ICGC;COSMIC	11.681	Up-regulation
CAMK_MAPKAPK_MK2_MAPKAPK2_ST	P04637	TP53	P49137	MAPKAPK2	S378	F385L	385	Missense	distal	7	no	13.171	13.394	EPSD	ICGC;COSMIC	11.681	Up-regulation
CAMK_MAPKAPK_MK2_MAPKAPK2_ST	P04637	TP53	P49137	MAPKAPK2	S378	G374C	374	Missense	distal	-4	no	13.171	13.073	EPSD	ICGC;COSMIC	11.681	Down-regulation
CAMK_MAPKAPK_MK2_MAPKAPK2_ST	P04637	TP53	P49137	MAPKAPK2	S378	R379S	379	Missense	proximal	1	no	13.171	13.148	EPSD	ICGC	11.681	Down-regulation
CAMK_MAPKAPK_MK2_MAPKAPK2_ST	P04637	TP53	P49137	MAPKAPK2	S378	R379C	379	Missense	proximal	1	no	13.171	12.910	EPSD	ICGC;COSMIC	11.681	Down-regulation
CAMK_MAPKAPK_MK2_MAPKAPK2_ST	Q14134	TRIM29	P49137	MAPKAPK2	S21	R17S	17	Missense	distal	-4	no	12.763	12.751	EPSD	ICGC	11.681	Down-regulation
CAMK_MAPKAPK_MK2_MAPKAPK2_ST	Q14134	TRIM29	P49137	MAPKAPK2	S23	R17S	17	Missense	distal	-6	no	18.844	18.832	EPSD	ICGC	11.681	Down-regulation
CAMK_MAPKAPK_MK2_MAPKAPK2_ST	Q14134	TRIM29	P49137	MAPKAPK2	S141	M143T	143	Missense	proximal	2	no	12.305	12.597	EPSD	ICGC	11.681	Up-regulation
CAMK_MAPKAPK_MK2_MAPKAPK2_ST	Q14134	TRIM29	P49137	MAPKAPK2	S301	A308D	308	Missense	distal	7	no	14.704	14.391	EPSD	ICGC	11.681	Down-regulation
CAMK_MAPKAPK_MK2_MAPKAPK2_ST	Q14134	TRIM29	P49137	MAPKAPK2	S301	S301P	301	Missense	central	0	yes	14.704	0.000	EPSD	ICGC;COSMIC	11.681	Loss
CAMK_MAPKAPK_MK2_MAPKAPK2_ST	Q14134	TRIM29	P49137	MAPKAPK2	S301	K294N	294	Missense	distal	-7	no	14.704	14.713	EPSD	ICGC;COSMIC	11.681	Up-regulation
CAMK_MAPKAPK_MK2_MAPKAPK2_ST	P09917	ALOX5	P49137	MAPKAPK2	S272	Q278H	278	Missense	distal	6	no	17.029	17.018	EPSD;PhosphoSitePlus	ICGC;COSMIC	11.681	Down-regulation
CAMK_MAPKAPK_MK2_MAPKAPK2_ST	P17844	DDX5	P49137	MAPKAPK2	S279	Q274K	274	Missense	distal	-5	no	11.872	11.779	EPSD	ICGC	11.681	Down-regulation
CAMK_MAPKAPK_MK2_MAPKAPK2_ST	P17844	DDX5	P49137	MAPKAPK2	S279	L276I	276	Missense	distal	-3	no	11.872	11.674	EPSD	ICGC	11.681	Loss
CAMK_MAPKAPK_MK2_MAPKAPK2_ST	P17844	DDX5	P49137	MAPKAPK2	S279	M277I	277	Missense	proximal	-2	no	11.872	9.656	EPSD	ICGC;COSMIC	11.681	Loss
CAMK_MAPKAPK_MK2_MAPKAPK2_ST	P17844	DDX5	P49137	MAPKAPK2	S519	R516S	516	Missense	distal	-3	no	13.223	6.894	EPSD	ICGC;COSMIC	11.681	Loss
CAMK_MAPKAPK_MK2_MAPKAPK2_ST	P17844	DDX5	P49137	MAPKAPK2	S519	L522R	522	Missense	distal	3	no	13.223	13.270	EPSD	ICGC;COSMIC	11.681	Up-regulation
CAMK_MAPKAPK_MK2_MAPKAPK2_ST	Q92904	DAZL	P49137	MAPKAPK2	S14	T12A	12	Missense	proximal	-2	no	11.770	11.929	EPSD	ICGC;COSMIC	11.681	Up-regulation
CAMK_MAPKAPK_MK2_MAPKAPK2_ST	Q92904	DAZL	P49137	MAPKAPK2	S14	N10K	10	Missense	distal	-4	no	11.770	11.804	EPSD	ICGC;COSMIC	11.681	Up-regulation
CAMK_MAPKAPK_MK2_MAPKAPK2_ST	Q92904	DAZL	P49137	MAPKAPK2	S65	I72N	72	Missense	distal	7	no	14.833	14.806	PhosphoSitePlus	ICGC;COSMIC	11.681	Down-regulation
CAMK_MAPKAPK_MK2_MAPKAPK2_ST	Q92904	DAZL	P49137	MAPKAPK2	S65	E68K	68	Missense	distal	3	no	14.833	14.705	PhosphoSitePlus	ICGC;COSMIC	11.681	Down-regulation
CAMK_MAPKAPK_MK2_MAPKAPK2_ST	Q13546	RIPK1	P49137	MAPKAPK2	S320	V315A	315	Missense	distal	-5	no	17.125	16.454	PhosphoSitePlus	ICGC;COSMIC	11.681	Down-regulation
CAMK_MAPKAPK_MK2_MAPKAPK2_ST	Q13546	RIPK1	P49137	MAPKAPK2	S320	R317I	317	Missense	distal	-3	no	17.125	11.836	PhosphoSitePlus	ICGC;COSMIC	11.681	Down-regulation
CAMK_MAPKAPK_MK2_MAPKAPK2_ST	Q13546	RIPK1	P49137	MAPKAPK2	S416	R413C	413	Missense	distal	-3	no	14.768	6.369	EPSD	ICGC;COSMIC	11.681	Loss
CAMK_MAPKAPK_MK2_MAPKAPK2_ST	P11831	SRF	P49137	MAPKAPK2	S103	G108C	108	Missense	distal	5	no	20.638	20.594	PhosphoSitePlus	ICGC	11.681	Down-regulation
CAMK_MAPKAPK_MK2_MAPKAPK2_ST	P11831	SRF	P49137	MAPKAPK2	S103	G97A	97	Missense	distal	-6	no	20.638	20.569	PhosphoSitePlus	ICGC	11.681	Down-regulation
CAMK_MAPKAPK_MK2_MAPKAPK2_ST	P11831	SRF	P49137	MAPKAPK2	S103	E104D	104	Missense	proximal	1	no	20.638	20.205	PhosphoSitePlus	ICGC;COSMIC	11.681	Down-regulation
CAMK_MAPKAPK_MK2_MAPKAPK2_ST	P11831	SRF	P49137	MAPKAPK2	S189	Y195H	195	Missense	distal	6	no	12.735	12.742	EPSD	ICGC;COSMIC	11.681	Up-regulation
CAMK_MAPKAPK_MK2_MAPKAPK2_ST	P11831	SRF	P49137	MAPKAPK2	S224	S221L	221	Missense	distal	-3	no	11.407	12.646	EPSD	ICGC;COSMIC	11.681	Gain
CAMK_MAPKAPK_MK2_MAPKAPK2_ST	P11831	SRF	P49137	MAPKAPK2	S237	A238S	238	Missense	proximal	1	no	11.669	11.729	EPSD	ICGC	11.681	Gain
CAMK_MAPKAPK_MK2_MAPKAPK2_ST	P11831	SRF	P49137	MAPKAPK2	S435	S439Y	439	Missense	distal	4	no	12.240	11.886	EPSD	ICGC;COSMIC	11.681	Down-regulation
CAMK_MAPKAPK_MK2_MAPKAPK2_ST	P11831	SRF	P49137	MAPKAPK2	S435	S435Y	435	Missense	central	0	yes	12.240	0.000	EPSD	ICGC;COSMIC	11.681	Loss
CAMK_MAPKAPK_MK2_MAPKAPK2_ST	Q13263	TRIM28	P49137	MAPKAPK2	S37	A40V	40	Missense	distal	3	no	12.267	12.163	EPSD	ICGC	11.681	Down-regulation
CAMK_MAPKAPK_MK2_MAPKAPK2_ST	Q13263	TRIM28	P49137	MAPKAPK2	S37	A44T	44	Missense	distal	7	no	12.267	12.369	EPSD	ICGC	11.681	Up-regulation
CAMK_MAPKAPK_MK2_MAPKAPK2_ST	Q13263	TRIM28	P49137	MAPKAPK2	S37	A38S	38	Missense	proximal	1	no	12.267	12.328	EPSD	ICGC;COSMIC	11.681	Up-regulation
CAMK_MAPKAPK_MK2_MAPKAPK2_ST	Q13263	TRIM28	P49137	MAPKAPK2	S41	A38S	38	Missense	distal	-3	no	9.307	12.198	EPSD	ICGC;COSMIC	11.681	Gain
CAMK_MAPKAPK_MK2_MAPKAPK2_ST	Q13263	TRIM28	P49137	MAPKAPK2	S43	A40V	40	Missense	distal	-3	no	11.362	12.854	EPSD	ICGC	11.681	Gain
CAMK_MAPKAPK_MK2_MAPKAPK2_ST	Q13263	TRIM28	P49137	MAPKAPK2	S43	A38S	38	Missense	distal	-5	no	11.362	11.846	EPSD	ICGC;COSMIC	11.681	Gain
CAMK_MAPKAPK_MK2_MAPKAPK2_ST	Q13263	TRIM28	P49137	MAPKAPK2	S285	V284M	284	Missense	proximal	-1	no	16.286	16.291	EPSD	ICGC	11.681	Up-regulation
CAMK_MAPKAPK_MK2_MAPKAPK2_ST	Q13263	TRIM28	P49137	MAPKAPK2	S473	G476S	476	Missense	distal	3	no	19.200	19.300	PhosphoSitePlus	ICGC;COSMIC	11.681	Up-regulation
CAMK_MAPKAPK_MK2_MAPKAPK2_ST	Q13263	TRIM28	P49137	MAPKAPK2	S501	P503A	503	Missense	proximal	2	no	12.041	12.204	EPSD	ICGC;COSMIC	11.681	Up-regulation
CAMK_MAPKAPK_MK2_MAPKAPK2_ST	Q13263	TRIM28	P49137	MAPKAPK2	S594	S598N	598	Missense	distal	4	no	14.830	14.637	EPSD	ICGC;GDSC;CCLE	11.681	Down-regulation
CAMK_MAPKAPK_MK2_MAPKAPK2_ST	Q13263	TRIM28	P49137	MAPKAPK2	S598	L603V	603	Missense	distal	5	no	14.103	14.117	EPSD	ICGC;COSMIC	11.681	Up-regulation
CAMK_MAPKAPK_MK2_MAPKAPK2_ST	Q13263	TRIM28	P49137	MAPKAPK2	S598	S598N	598	Missense	central	0	yes	14.103	0.000	EPSD	ICGC;GDSC;CCLE	11.681	Loss
CAMK_MAPKAPK_MK2_MAPKAPK2_ST	P33241	LSP1	P49137	MAPKAPK2	S141	E136V	136	Missense	distal	-5	no	13.588	13.826	EPSD	ICGC	11.681	Up-regulation
CAMK_MAPKAPK_MK2_MAPKAPK2_ST	P33241	LSP1	P49137	MAPKAPK2	S141	L135M	135	Missense	distal	-6	no	13.588	13.598	EPSD	ICGC;COSMIC	11.681	Up-regulation
CAMK_MAPKAPK_MK2_MAPKAPK2_ST	P33241	LSP1	P49137	MAPKAPK2	S141	E143K	143	Missense	proximal	2	no	13.588	13.289	EPSD	ICGC;COSMIC	11.681	Down-regulation
CAMK_MAPKAPK_MK2_MAPKAPK2_ST	P33241	LSP1	P49137	MAPKAPK2	S141	P147Q	147	Missense	distal	6	no	13.588	13.582	EPSD	ICGC;COSMIC	11.681	Down-regulation
CAMK_MAPKAPK_MK2_MAPKAPK2_ST	P33241	LSP1	P49137	MAPKAPK2	S177	T175P	175	Missense	proximal	-2	no	17.187	15.709	EPSD	ICGC;COSMIC	11.681	Down-regulation
CAMK_MAPKAPK_MK2_MAPKAPK2_ST	P33241	LSP1	P49137	MAPKAPK2	S177	P173L	173	Missense	distal	-4	no	17.187	17.311	EPSD	ICGC	11.681	Up-regulation
CAMK_MAPKAPK_MK2_MAPKAPK2_ST	P33241	LSP1	P49137	MAPKAPK2	S189	I185N	185	Missense	distal	-4	no	13.928	14.005	EPSD	ICGC;COSMIC	11.681	Up-regulation
CAMK_MAPKAPK_MK2_MAPKAPK2_ST	P33241	LSP1	P49137	MAPKAPK2	S189	E186K	186	Missense	distal	-3	no	13.928	14.099	EPSD	ICGC;COSMIC	11.681	Up-regulation
CAMK_MAPKAPK_MK2_MAPKAPK2_ST	P33241	LSP1	P49137	MAPKAPK2	S189	E186G	186	Missense	distal	-3	no	13.928	8.563	EPSD	ICGC;COSMIC	11.681	Loss
CAMK_MAPKAPK_MK2_MAPKAPK2_ST	P33241	LSP1	P49137	MAPKAPK2	S193	E186K	186	Missense	distal	-7	no	12.194	12.233	EPSD	ICGC;COSMIC	11.681	Up-regulation
CAMK_MAPKAPK_MK2_MAPKAPK2_ST	P33241	LSP1	P49137	MAPKAPK2	S193	E186G	186	Missense	distal	-7	no	12.194	12.251	EPSD	ICGC;COSMIC	11.681	Up-regulation
CAMK_MAPKAPK_MK2_MAPKAPK2_ST	P33241	LSP1	P49137	MAPKAPK2	S204	S204Y	204	Missense	central	0	yes	18.238	0.000	EPSD	ICGC;COSMIC	11.681	Loss
CAMK_MAPKAPK_MK2_MAPKAPK2_ST	P33241	LSP1	P49137	MAPKAPK2	S204	S208Y	208	Missense	distal	4	no	18.238	17.884	EPSD	ICGC	11.681	Down-regulation
CAMK_MAPKAPK_MK2_MAPKAPK2_ST	P33241	LSP1	P49137	MAPKAPK2	S204	T202I	202	Missense	proximal	-2	no	18.238	15.651	EPSD	ICGC	11.681	Down-regulation
CAMK_MAPKAPK_MK2_MAPKAPK2_ST	P33241	LSP1	P49137	MAPKAPK2	S204	E210D	210	Missense	distal	6	no	18.238	18.223	EPSD	ICGC;GDSC;CCLE	11.681	Down-regulation
CAMK_MAPKAPK_MK2_MAPKAPK2_ST	P33241	LSP1	P49137	MAPKAPK2	S214	K216N	216	Missense	proximal	2	no	13.750	13.841	EPSD	ICGC;COSMIC	11.681	Up-regulation
CAMK_MAPKAPK_MK2_MAPKAPK2_ST	P33241	LSP1	P49137	MAPKAPK2	S214	D221Y	221	Missense	distal	7	no	13.750	13.367	EPSD	ICGC;COSMIC	11.681	Down-regulation
CAMK_MAPKAPK_MK2_MAPKAPK2_ST	P33241	LSP1	P49137	MAPKAPK2	S214	S208Y	208	Missense	distal	-6	no	13.750	13.853	EPSD	ICGC	11.681	Up-regulation
CAMK_MAPKAPK_MK2_MAPKAPK2_ST	P33241	LSP1	P49137	MAPKAPK2	S214	E210D	210	Missense	distal	-4	no	13.750	13.921	EPSD	ICGC;GDSC;CCLE	11.681	Up-regulation
CAMK_MAPKAPK_MK2_MAPKAPK2_ST	P33241	LSP1	P49137	MAPKAPK2	S252	Q250H	250	Missense	proximal	-2	no	19.119	16.681	PhosphoSitePlus	ICGC;COSMIC	11.681	Down-regulation
CAMK_MAPKAPK_MK2_MAPKAPK2_ST	P33241	LSP1	P49137	MAPKAPK2	S252	R249C	249	Missense	distal	-3	no	19.119	10.720	PhosphoSitePlus	ICGC;COSMIC	11.681	Loss
CAMK_MAPKAPK_MK2_MAPKAPK2_ST	P33241	LSP1	P49137	MAPKAPK2	S257	Q250H	250	Missense	distal	-7	no	12.185	12.189	EPSD	ICGC;COSMIC	11.681	Up-regulation
CAMK_MAPKAPK_MK2_MAPKAPK2_ST	P33241	LSP1	P49137	MAPKAPK2	S257	A261V	261	Missense	distal	4	no	12.185	12.034	EPSD	ICGC;COSMIC	11.681	Down-regulation
CAMK_MAPKAPK_MK2_MAPKAPK2_ST	P33241	LSP1	P49137	MAPKAPK2	S265	R266Q	266	Missense	proximal	1	no	12.598	12.145	EPSD	ICGC;COSMIC	11.681	Down-regulation
CAMK_MAPKAPK_MK2_MAPKAPK2_ST	P33241	LSP1	P49137	MAPKAPK2	S265	A261V	261	Missense	distal	-4	no	12.598	12.677	EPSD	ICGC;COSMIC	11.681	Up-regulation
CAMK_MAPKAPK_MK2_MAPKAPK2_ST	P33241	LSP1	P49137	MAPKAPK2	S276	A274T	274	Missense	proximal	-2	no	13.318	13.159	EPSD	ICGC	11.681	Down-regulation
CAMK_MAPKAPK_MK2_MAPKAPK2_ST	P33241	LSP1	P49137	MAPKAPK2	S276	K279N	279	Missense	distal	3	no	13.318	13.305	EPSD	ICGC;COSMIC	11.681	Down-regulation
CAMK_MAPKAPK_MK2_MAPKAPK2_ST	P33241	LSP1	P49137	MAPKAPK2	S292	G289R	289	Missense	distal	-3	no	4.962	15.622	EPSD	ICGC	11.681	Gain
CAMK_MAPKAPK_MK2_MAPKAPK2_ST	O75925	PIAS1	P49137	MAPKAPK2	S158	S155R	155	Missense	distal	-3	no	8.441	14.770	EPSD	ICGC	11.681	Gain
CAMK_MAPKAPK_MK2_MAPKAPK2_ST	O75925	PIAS1	P49137	MAPKAPK2	S289	Y283H	283	Missense	distal	-6	no	12.924	12.897	EPSD	ICGC;COSMIC	11.681	Down-regulation
CAMK_MAPKAPK_MK2_MAPKAPK2_ST	O75925	PIAS1	P49137	MAPKAPK2	S289	V292F	292	Missense	distal	3	no	12.924	12.771	EPSD	ICGC	11.681	Down-regulation
CAMK_MAPKAPK_MK2_MAPKAPK2_ST	O75925	PIAS1	P49137	MAPKAPK2	S289	R296M	296	Missense	distal	7	no	12.924	12.750	EPSD	ICGC	11.681	Down-regulation
CAMK_MAPKAPK_MK2_MAPKAPK2_ST	O75925	PIAS1	P49137	MAPKAPK2	S485	R479G	479	Missense	distal	-6	no	14.895	14.967	EPSD	ICGC;COSMIC	11.681	Up-regulation
CAMK_MAPKAPK_MK2_MAPKAPK2_ST	O75925	PIAS1	P49137	MAPKAPK2	S503	A502S	502	Missense	proximal	-1	no	11.873	11.869	EPSD	ICGC	11.681	Down-regulation
CAMK_MAPKAPK_MK2_MAPKAPK2_ST	O75925	PIAS1	P49137	MAPKAPK2	S503	R507S	507	Missense	distal	4	no	11.873	11.938	EPSD	ICGC;COSMIC	11.681	Up-regulation
CAMK_MAPKAPK_MK2_MAPKAPK2_ST	O75925	PIAS1	P49137	MAPKAPK2	S510	A513V	513	Missense	distal	3	no	17.412	17.307	EPSD	ICGC	11.681	Down-regulation
CAMK_MAPKAPK_MK2_MAPKAPK2_ST	O75925	PIAS1	P49137	MAPKAPK2	S510	V514L	514	Missense	distal	4	no	17.412	17.387	EPSD	ICGC;COSMIC	11.681	Down-regulation
CAMK_MAPKAPK_MK2_MAPKAPK2_ST	O75925	PIAS1	P49137	MAPKAPK2	S510	R507S	507	Missense	distal	-3	no	17.412	11.082	EPSD	ICGC;COSMIC	11.681	Loss
CAMK_MAPKAPK_MK2_MAPKAPK2_ST	O75925	PIAS1	P49137	MAPKAPK2	S522	I519M	519	Missense	distal	-3	no	12.530	9.428	PhosphoSitePlus	ICGC;COSMIC	11.681	Loss
CAMK_MAPKAPK_MK2_MAPKAPK2_ST	O75925	PIAS1	P49137	MAPKAPK2	T635	T635M	635	Missense	central	0	yes	14.759	0.000	EPSD	ICGC	11.681	Loss
CAMK_MAPKAPK_MK2_MAPKAPK2_ST	Q9NY61	AATF	P49137	MAPKAPK2	S20	E21A	21	Missense	proximal	1	no	13.145	13.002	EPSD	ICGC	11.681	Down-regulation
CAMK_MAPKAPK_MK2_MAPKAPK2_ST	Q9NY61	AATF	P49137	MAPKAPK2	S94	G92R	92	Missense	proximal	-2	no	11.112	12.182	EPSD	ICGC	11.681	Gain
CAMK_MAPKAPK_MK2_MAPKAPK2_ST	Q9NY61	AATF	P49137	MAPKAPK2	S141	P147L	147	Missense	distal	6	no	14.027	14.023	EPSD	ICGC	11.681	Down-regulation
CAMK_MAPKAPK_MK2_MAPKAPK2_ST	Q9NY61	AATF	P49137	MAPKAPK2	S141	K138E	138	Missense	distal	-3	no	14.027	13.856	EPSD	ICGC	11.681	Down-regulation
CAMK_MAPKAPK_MK2_MAPKAPK2_ST	Q9NY61	AATF	P49137	MAPKAPK2	S143	P147L	147	Missense	distal	4	no	19.058	18.965	EPSD	ICGC	11.681	Down-regulation
CAMK_MAPKAPK_MK2_MAPKAPK2_ST	Q9NY61	AATF	P49137	MAPKAPK2	S143	K138E	138	Missense	distal	-5	no	19.058	19.666	EPSD	ICGC	11.681	Up-regulation
CAMK_MAPKAPK_MK2_MAPKAPK2_ST	Q9NY61	AATF	P49137	MAPKAPK2	T412	R414C	414	Missense	proximal	2	no	13.095	12.800	EPSD	ICGC	11.681	Down-regulation
CAMK_MAPKAPK_MK2_MAPKAPK2_ST	Q9NY61	AATF	P49137	MAPKAPK2	S510	K503R	503	Missense	distal	-7	no	13.918	13.843	EPSD	ICGC	11.681	Down-regulation
CAMK_MAPKAPK_MK2_MAPKAPK2_ST	Q9NY61	AATF	P49137	MAPKAPK2	S510	K504N	504	Missense	distal	-6	no	13.918	13.921	EPSD	ICGC	11.681	Up-regulation
CAMK_MAPKAPK_MK2_MAPKAPK2_ST	Q9NY61	AATF	P49137	MAPKAPK2	S510	R507K	507	Missense	distal	-3	no	13.918	8.794	EPSD	ICGC	11.681	Loss
CAMK_MAPKAPK_MK2_MAPKAPK2_ST	Q9NY61	AATF	P49137	MAPKAPK2	S510	R507M	507	Missense	distal	-3	no	13.918	5.527	EPSD	ICGC	11.681	Loss
CAMK_MAPKAPK_MK2_MAPKAPK2_ST	Q00613	HSF1	P49137	MAPKAPK2	S218	P223L	223	Missense	distal	5	no	12.045	12.131	EPSD	ICGC	11.681	Up-regulation
CAMK_MAPKAPK_MK2_MAPKAPK2_ST	Q00613	HSF1	P49137	MAPKAPK2	S218	M212V	212	Missense	distal	-6	no	12.045	12.048	EPSD	ICGC	11.681	Up-regulation
CAMK_MAPKAPK_MK2_MAPKAPK2_ST	Q00613	HSF1	P49137	MAPKAPK2	S230	P223L	223	Missense	distal	-7	no	18.051	18.085	EPSD	ICGC	11.681	Up-regulation
CAMK_MAPKAPK_MK2_MAPKAPK2_ST	Q00613	HSF1	P49137	MAPKAPK2	S279	A278T	278	Missense	proximal	-1	no	11.909	11.901	EPSD	ICGC	11.681	Down-regulation
CAMK_MAPKAPK_MK2_MAPKAPK2_ST	Q00613	HSF1	P49137	MAPKAPK2	S283	A278T	278	Missense	distal	-5	no	11.368	11.771	EPSD	ICGC	11.681	Gain
CAMK_MAPKAPK_MK2_MAPKAPK2_ST	Q00613	HSF1	P49137	MAPKAPK2	S518	A523V	523	Missense	distal	5	no	12.535	12.679	EPSD	ICGC;COSMIC	11.681	Up-regulation
CAMK_MAPKAPK_MK2_MAPKAPK2_ST	Q07817	BCL2L1	P49137	MAPKAPK2	S49	E44D	44	Missense	distal	-5	no	13.185	12.460	EPSD	ICGC;COSMIC	11.681	Down-regulation
CAMK_MAPKAPK_MK2_MAPKAPK2_ST	Q07817	BCL2L1	P49137	MAPKAPK2	S49	T47I	47	Missense	proximal	-2	no	13.185	10.597	EPSD	ICGC;COSMIC	11.681	Loss
CAMK_MAPKAPK_MK2_MAPKAPK2_ST	Q07817	BCL2L1	P49137	MAPKAPK2	S62	P63T	63	Missense	proximal	1	no	12.896	12.932	PhosphoSitePlus	ICGC	11.681	Up-regulation
CAMK_MAPKAPK_MK2_MAPKAPK2_ST	Q16875	PFKFB3	P49137	MAPKAPK2	S22	V17I	17	Missense	distal	-5	no	12.182	12.301	EPSD	ICGC;COSMIC	11.681	Up-regulation
CAMK_MAPKAPK_MK2_MAPKAPK2_ST	Q16875	PFKFB3	P49137	MAPKAPK2	S22	V17M	17	Missense	distal	-5	no	12.182	11.734	EPSD	ICGC;COSMIC	11.681	Down-regulation
CAMK_MAPKAPK_MK2_MAPKAPK2_ST	Q16875	PFKFB3	P49137	MAPKAPK2	S211	D209Y	209	Missense	proximal	-2	no	14.175	13.663	EPSD	ICGC	11.681	Down-regulation
CAMK_MAPKAPK_MK2_MAPKAPK2_ST	Q16875	PFKFB3	P49137	MAPKAPK2	S446	R443L	443	Missense	distal	-3	no	16.027	10.936	EPSD	ICGC;COSMIC	11.681	Loss
CAMK_MAPKAPK_MK2_MAPKAPK2_ST	P49815	TSC2	P49137	MAPKAPK2	S311	S315L	315	Missense	distal	4	no	14.604	14.451	EPSD	ICGC;COSMIC	11.681	Down-regulation
CAMK_MAPKAPK_MK2_MAPKAPK2_ST	P49815	TSC2	P49137	MAPKAPK2	S311	R308L	308	Missense	distal	-3	no	14.604	9.513	EPSD	ICGC;COSMIC	11.681	Loss
CAMK_MAPKAPK_MK2_MAPKAPK2_ST	P49815	TSC2	P49137	MAPKAPK2	S311	A306D	306	Missense	distal	-5	no	14.604	14.312	EPSD	ICGC;COSMIC	11.681	Down-regulation
CAMK_MAPKAPK_MK2_MAPKAPK2_ST	P49815	TSC2	P49137	MAPKAPK2	S540	R537L	537	Missense	distal	-3	no	19.462	14.371	EPSD	ICGC	11.681	Down-regulation
CAMK_MAPKAPK_MK2_MAPKAPK2_ST	P49815	TSC2	P49137	MAPKAPK2	S609	Y602H	602	Missense	distal	-7	no	12.074	12.055	EPSD	ICGC;COSMIC;GDSC;CCLE	11.681	Down-regulation
CAMK_MAPKAPK_MK2_MAPKAPK2_ST	P49815	TSC2	P49137	MAPKAPK2	S609	A607T	607	Missense	proximal	-2	no	12.074	11.915	EPSD	ICGC;COSMIC;GDSC	11.681	Down-regulation
CAMK_MAPKAPK_MK2_MAPKAPK2_ST	P49815	TSC2	P49137	MAPKAPK2	S937	R934M	934	Missense	distal	-3	no	18.542	10.151	EPSD	ICGC;COSMIC	11.681	Loss
CAMK_MAPKAPK_MK2_MAPKAPK2_ST	P49815	TSC2	P49137	MAPKAPK2	S939	R934M	934	Missense	distal	-5	no	19.644	19.230	EPSD	ICGC;COSMIC	11.681	Down-regulation
CAMK_MAPKAPK_MK2_MAPKAPK2_ST	P49815	TSC2	P49137	MAPKAPK2	S946	A950S	950	Missense	distal	4	no	16.852	16.829	EPSD	ICGC	11.681	Down-regulation
CAMK_MAPKAPK_MK2_MAPKAPK2_ST	P49815	TSC2	P49137	MAPKAPK2	S979	R976Q	976	Missense	distal	-3	no	16.711	10.947	EPSD	ICGC;COSMIC	11.681	Loss
CAMK_MAPKAPK_MK2_MAPKAPK2_ST	P49815	TSC2	P49137	MAPKAPK2	S979	R978C	978	Missense	proximal	-1	no	16.711	16.732	EPSD	ICGC;COSMIC	11.681	Up-regulation
CAMK_MAPKAPK_MK2_MAPKAPK2_ST	P49815	TSC2	P49137	MAPKAPK2	S979	E973K	973	Missense	distal	-6	no	16.711	16.774	EPSD	ICGC;COSMIC	11.681	Up-regulation
CAMK_MAPKAPK_MK2_MAPKAPK2_ST	P49815	TSC2	P49137	MAPKAPK2	S979	R976G	976	Missense	distal	-3	no	16.711	6.052	EPSD	ICGC	11.681	Loss
CAMK_MAPKAPK_MK2_MAPKAPK2_ST	P49815	TSC2	P49137	MAPKAPK2	S979	V986M	986	Missense	distal	7	no	16.711	16.790	EPSD	ICGC	11.681	Up-regulation
CAMK_MAPKAPK_MK2_MAPKAPK2_ST	P49815	TSC2	P49137	MAPKAPK2	S981	R976Q	976	Missense	distal	-5	no	21.035	20.317	EPSD	ICGC;COSMIC	11.681	Down-regulation
CAMK_MAPKAPK_MK2_MAPKAPK2_ST	P49815	TSC2	P49137	MAPKAPK2	S981	R978C	978	Missense	distal	-3	no	21.035	12.636	EPSD	ICGC;COSMIC	11.681	Down-regulation
CAMK_MAPKAPK_MK2_MAPKAPK2_ST	P49815	TSC2	P49137	MAPKAPK2	S981	R988L	988	Missense	distal	7	no	21.035	20.651	EPSD	ICGC	11.681	Down-regulation
CAMK_MAPKAPK_MK2_MAPKAPK2_ST	P49815	TSC2	P49137	MAPKAPK2	S981	R988H	988	Missense	distal	7	no	21.035	20.571	EPSD	ICGC	11.681	Down-regulation
CAMK_MAPKAPK_MK2_MAPKAPK2_ST	P49815	TSC2	P49137	MAPKAPK2	S981	R976G	976	Missense	distal	-5	no	21.035	20.003	EPSD	ICGC	11.681	Down-regulation
CAMK_MAPKAPK_MK2_MAPKAPK2_ST	P49815	TSC2	P49137	MAPKAPK2	S981	V986M	986	Missense	distal	5	no	21.035	20.990	EPSD	ICGC	11.681	Down-regulation
CAMK_MAPKAPK_MK2_MAPKAPK2_ST	P49815	TSC2	P49137	MAPKAPK2	S983	R976Q	976	Missense	distal	-7	no	12.332	12.419	EPSD	ICGC;COSMIC	11.681	Up-regulation
CAMK_MAPKAPK_MK2_MAPKAPK2_ST	P49815	TSC2	P49137	MAPKAPK2	S983	R978C	978	Missense	distal	-5	no	12.332	11.727	EPSD	ICGC;COSMIC	11.681	Down-regulation
CAMK_MAPKAPK_MK2_MAPKAPK2_ST	P49815	TSC2	P49137	MAPKAPK2	S983	R988L	988	Missense	distal	5	no	12.332	12.483	EPSD	ICGC	11.681	Up-regulation
CAMK_MAPKAPK_MK2_MAPKAPK2_ST	P49815	TSC2	P49137	MAPKAPK2	S983	R988H	988	Missense	distal	5	no	12.332	12.638	EPSD	ICGC	11.681	Up-regulation
CAMK_MAPKAPK_MK2_MAPKAPK2_ST	P49815	TSC2	P49137	MAPKAPK2	S983	R976G	976	Missense	distal	-7	no	12.332	12.425	EPSD	ICGC	11.681	Up-regulation
CAMK_MAPKAPK_MK2_MAPKAPK2_ST	P49815	TSC2	P49137	MAPKAPK2	S983	V986M	986	Missense	distal	3	no	12.332	12.326	EPSD	ICGC	11.681	Down-regulation
CAMK_MAPKAPK_MK2_MAPKAPK2_ST	P49815	TSC2	P49137	MAPKAPK2	S999	S1002F	1002	Missense	distal	3	no	13.470	13.258	EPSD	ICGC;COSMIC	11.681	Down-regulation
CAMK_MAPKAPK_MK2_MAPKAPK2_ST	P49815	TSC2	P49137	MAPKAPK2	S999	S1002Y	1002	Missense	distal	3	no	13.470	13.220	EPSD	ICGC;COSMIC	11.681	Down-regulation
CAMK_MAPKAPK_MK2_MAPKAPK2_ST	P49815	TSC2	P49137	MAPKAPK2	S1254	V1255M	1255	Missense	proximal	1	no	15.117	14.758	PhosphoSitePlus	ICGC;COSMIC	11.681	Down-regulation
CAMK_MAPKAPK_MK2_MAPKAPK2_ST	P49815	TSC2	P49137	MAPKAPK2	S1259	V1255M	1255	Missense	distal	-4	no	12.844	12.792	EPSD	ICGC;COSMIC	11.681	Down-regulation
CAMK_MAPKAPK_MK2_MAPKAPK2_ST	P49815	TSC2	P49137	MAPKAPK2	S1336	S1336L	1336	Missense	central	0	yes	12.197	0.000	EPSD	ICGC;COSMIC	11.681	Loss
CAMK_MAPKAPK_MK2_MAPKAPK2_ST	P49815	TSC2	P49137	MAPKAPK2	S1338	S1336L	1336	Missense	proximal	-2	no	19.408	16.051	EPSD	ICGC;COSMIC	11.681	Down-regulation
CAMK_MAPKAPK_MK2_MAPKAPK2_ST	P49815	TSC2	P49137	MAPKAPK2	S1340	S1336L	1336	Missense	distal	-4	no	13.750	13.954	EPSD	ICGC;COSMIC	11.681	Up-regulation
CAMK_MAPKAPK_MK2_MAPKAPK2_ST	P49815	TSC2	P49137	MAPKAPK2	S1385	S1388L	1388	Missense	distal	3	no	11.883	11.768	EPSD	ICGC;COSMIC	11.681	Down-regulation
CAMK_MAPKAPK_MK2_MAPKAPK2_ST	P49815	TSC2	P49137	MAPKAPK2	S1387	S1388L	1388	Missense	proximal	1	no	13.645	13.846	EPSD	ICGC;COSMIC	11.681	Up-regulation
CAMK_MAPKAPK_MK2_MAPKAPK2_ST	P49815	TSC2	P49137	MAPKAPK2	S1388	S1388L	1388	Missense	central	0	yes	12.312	0.000	EPSD	ICGC;COSMIC	11.681	Loss
CAMK_MAPKAPK_MK2_MAPKAPK2_ST	P30307	CDC25C	P49137	MAPKAPK2	S38	L33P	33	Missense	distal	-5	no	14.586	14.081	EPSD	ICGC;COSMIC	11.681	Down-regulation
CAMK_MAPKAPK_MK2_MAPKAPK2_ST	P30307	CDC25C	P49137	MAPKAPK2	S57	G55S	55	Missense	proximal	-2	no	10.111	13.449	EPSD	ICGC;COSMIC	11.681	Gain
CAMK_MAPKAPK_MK2_MAPKAPK2_ST	P30307	CDC25C	P49137	MAPKAPK2	S216	E219D	219	Missense	distal	3	no	19.967	19.874	PhosphoSitePlus	ICGC;COSMIC	11.681	Down-regulation
CAMK_MAPKAPK_MK2_MAPKAPK2_ST	P30307	CDC25C	P49137	MAPKAPK2	S449	G456V	456	Missense	distal	7	no	13.827	13.808	EPSD	ICGC;COSMIC	11.681	Down-regulation
CAMK_MAPKAPK_MK2_MAPKAPK2_ST	P30307	CDC25C	P49137	MAPKAPK2	S451	G456V	456	Missense	distal	5	no	18.092	17.985	EPSD	ICGC;COSMIC	11.681	Down-regulation
CAMK_MAPKAPK_MK2_MAPKAPK2_ST	Q14457	BECN1	P49137	MAPKAPK2	S15	M12I	12	Missense	distal	-3	no	8.724	11.826	EPSD	ICGC;COSMIC	11.681	Gain
CAMK_MAPKAPK_MK2_MAPKAPK2_ST	Q14457	BECN1	P49137	MAPKAPK2	S64	P68T	68	Missense	distal	4	no	11.915	12.022	EPSD	ICGC;COSMIC	11.681	Up-regulation
CAMK_MAPKAPK_MK2_MAPKAPK2_ST	Q14457	BECN1	P49137	MAPKAPK2	S90	P85Q	85	Missense	distal	-5	no	16.933	16.379	PhosphoSitePlus	ICGC	11.681	Down-regulation
CAMK_MAPKAPK_MK2_MAPKAPK2_ST	Q14457	BECN1	P49137	MAPKAPK2	S96	A103E	103	Missense	distal	7	no	13.051	12.928	EPSD	ICGC	11.681	Down-regulation
CAMK_MAPKAPK_MK2_MAPKAPK2_ST	Q14457	BECN1	P49137	MAPKAPK2	S234	Q240K	240	Missense	distal	6	no	15.218	15.210	EPSD	ICGC	11.681	Down-regulation
CAMK_MAPKAPK_MK2_MAPKAPK2_ST	Q14457	BECN1	P49137	MAPKAPK2	S234	Q230H	230	Missense	distal	-4	no	15.218	15.268	EPSD	ICGC;COSMIC	11.681	Up-regulation
CAMK_MAPKAPK_MK2_MAPKAPK2_ST	Q14457	BECN1	P49137	MAPKAPK2	S295	P294H	294	Missense	proximal	-1	no	15.735	15.746	EPSD	ICGC	11.681	Up-regulation
CAMK_MAPKAPK_MK2_MAPKAPK2_ST	Q14457	BECN1	P49137	MAPKAPK2	S295	P297T	297	Missense	proximal	2	no	15.735	15.950	EPSD	ICGC	11.681	Up-regulation
CAMK_MAPKAPK_MK2_MAPKAPK2_ST	Q14457	BECN1	P49137	MAPKAPK2	S337	G334R	334	Missense	distal	-3	no	4.482	15.141	EPSD	ICGC;COSMIC	11.681	Gain
CAMK_MAPKAPK_MK2_MAPKAPK2_ST	P35900	KRT20	P49137	MAPKAPK2	S13	H9N	9	Missense	distal	-4	no	19.361	19.331	PhosphoSitePlus	ICGC;COSMIC	11.681	Down-regulation
CAMK_MAPKAPK_MK2_MAPKAPK2_ST	P35900	KRT20	P49137	MAPKAPK2	S13	S11R	11	Missense	proximal	-2	no	19.361	17.094	PhosphoSitePlus	ICGC;COSMIC	11.681	Down-regulation
CAMK_MAPKAPK_MK2_MAPKAPK2_ST	P35900	KRT20	P49137	MAPKAPK2	S14	S11R	11	Missense	distal	-3	no	8.951	15.280	EPSD	ICGC;COSMIC	11.681	Gain
CAMK_MAPKAPK_MK2_MAPKAPK2_ST	P35900	KRT20	P49137	MAPKAPK2	S15	H9N	9	Missense	distal	-6	no	13.805	13.801	EPSD	ICGC;COSMIC	11.681	Down-regulation
CAMK_MAPKAPK_MK2_MAPKAPK2_ST	P35900	KRT20	P49137	MAPKAPK2	S15	S11R	11	Missense	distal	-4	no	13.805	13.816	EPSD	ICGC;COSMIC	11.681	Up-regulation
CAMK_MAPKAPK_MK2_MAPKAPK2_ST	P35900	KRT20	P49137	MAPKAPK2	T31	V35I	35	Missense	distal	4	no	13.404	13.343	EPSD	ICGC	11.681	Down-regulation
CAMK_MAPKAPK_MK2_MAPKAPK2_ST	P35900	KRT20	P49137	MAPKAPK2	T31	R28H	28	Missense	distal	-3	no	13.404	8.644	EPSD	ICGC;COSMIC	11.681	Loss
CAMK_MAPKAPK_MK2_MAPKAPK2_ST	P35900	KRT20	P49137	MAPKAPK2	T31	G30R	30	Missense	proximal	-1	no	13.404	13.376	EPSD	ICGC;COSMIC	11.681	Down-regulation
CAMK_MAPKAPK_MK2_MAPKAPK2_ST	P35900	KRT20	P49137	MAPKAPK2	S34	V35I	35	Missense	proximal	1	no	12.843	12.751	EPSD	ICGC	11.681	Down-regulation
CAMK_MAPKAPK_MK2_MAPKAPK2_ST	P35900	KRT20	P49137	MAPKAPK2	S34	R28H	28	Missense	distal	-6	no	12.843	12.907	EPSD	ICGC;COSMIC	11.681	Up-regulation
CAMK_MAPKAPK_MK2_MAPKAPK2_ST	P35900	KRT20	P49137	MAPKAPK2	S34	G30R	30	Missense	distal	-4	no	12.843	12.517	EPSD	ICGC;COSMIC	11.681	Down-regulation
CAMK_MAPKAPK_MK2_MAPKAPK2_ST	P35900	KRT20	P49137	MAPKAPK2	S83	A82V	82	Missense	proximal	-1	no	13.206	13.205	EPSD	ICGC;COSMIC	11.681	Down-regulation
CAMK_MAPKAPK_MK2_MAPKAPK2_ST	P35900	KRT20	P49137	MAPKAPK2	S83	R80C	80	Missense	distal	-3	no	13.206	4.806	EPSD	ICGC;COSMIC	11.681	Loss
CAMK_MAPKAPK_MK2_MAPKAPK2_ST	P35900	KRT20	P49137	MAPKAPK2	S83	R80H	80	Missense	distal	-3	no	13.206	8.447	EPSD	ICGC;COSMIC	11.681	Loss
CAMK_MAPKAPK_MK2_MAPKAPK2_ST	P35900	KRT20	P49137	MAPKAPK2	S96	L98R	98	Missense	proximal	2	no	13.788	14.099	EPSD	ICGC	11.681	Up-regulation
CAMK_MAPKAPK_MK2_MAPKAPK2_ST	P35900	KRT20	P49137	MAPKAPK2	S118	A113D	113	Missense	distal	-5	no	12.619	12.327	EPSD	ICGC;COSMIC	11.681	Down-regulation
CAMK_MAPKAPK_MK2_MAPKAPK2_ST	P35900	KRT20	P49137	MAPKAPK2	S118	G114D	114	Missense	distal	-4	no	12.619	12.541	EPSD	ICGC;COSMIC	11.681	Down-regulation
CAMK_MAPKAPK_MK2_MAPKAPK2_ST	P35900	KRT20	P49137	MAPKAPK2	S293	T292A	292	Missense	proximal	-1	no	17.428	17.436	EPSD	ICGC;COSMIC	11.681	Up-regulation
CAMK_MAPKAPK_MK2_MAPKAPK2_ST	P35900	KRT20	P49137	MAPKAPK2	S295	T292A	292	Missense	distal	-3	no	12.513	9.168	EPSD	ICGC;COSMIC	11.681	Loss
CAMK_MAPKAPK_MK2_MAPKAPK2_ST	P35900	KRT20	P49137	MAPKAPK2	S295	S302Y	302	Missense	distal	7	no	12.513	12.018	EPSD	ICGC;COSMIC	11.681	Down-regulation
CAMK_CAMKL_MARK_MARK3_ST	P27448	MARK3	P27448-3	MARK3	S383	S390I	390	Missense	distal	7	no	295.051	294.978	EPSD	ICGC	255.132	Down-regulation
CAMK_CAMKL_MARK_MARK3_ST	P27448	MARK3	P27448-3	MARK3	S383	N381Y	381	Missense	proximal	-2	no	295.051	281.011	EPSD	ICGC	255.132	Down-regulation
CAMK_CAMKL_MARK_MARK3_ST	P27448	MARK3	P27448-3	MARK3	S390	S390I	390	Missense	central	0	yes	263.021	0.000	EPSD	ICGC	255.132	Loss
CAMK_CAMKL_MARK_MARK3_ST	P27448	MARK3	P27448-3	MARK3	S391	S390I	390	Missense	proximal	-1	no	258.245	258.291	EPSD	ICGC	255.132	Up-regulation
CAMK_CAMKL_MARK_MARK3_ST	P27448	MARK3	P27448-3	MARK3	S436	A431S	431	Missense	distal	-5	no	265.635	274.419	EPSD	ICGC	255.132	Up-regulation
CAMK_CAMKL_MARK_MARK3_ST	P27448	MARK3	P27448-3	MARK3	S436	V430L	430	Missense	distal	-6	no	265.635	264.421	EPSD	ICGC	255.132	Down-regulation
CAMK_CAMKL_MARK_MARK3_ST	P27448	MARK3	P27448-3	MARK3	S436	S443G	443	Missense	distal	7	no	265.635	264.734	EPSD	ICGC;COSMIC	255.132	Down-regulation
CAMK_CAMKL_MARK_MARK3_ST	P27448	MARK3	P27448-3	MARK3	S451	S451Y	451	Missense	central	0	yes	317.408	0.000	EPSD	ICGC	255.132	Loss
CAMK_CAMKL_MARK_MARK3_ST	P27448	MARK3	P27448-3	MARK3	S452	S451Y	451	Missense	proximal	-1	no	394.378	394.284	EPSD	ICGC	255.132	Down-regulation
CAMK_CAMKL_MARK_MARK3_ST	P27448	MARK3	P27448-3	MARK3	S455	S451Y	451	Missense	distal	-4	no	258.075	251.514	EPSD	ICGC	255.132	Loss
CAMK_CAMKL_MARK_MARK3_ST	P27448	MARK3	P27448-3	MARK3	S458	S451Y	451	Missense	distal	-7	no	318.747	313.322	EPSD	ICGC	255.132	Down-regulation
CAMK_CAMKL_MARK_MARK3_ST	P27448	MARK3	P27448-3	MARK3	S458	K463E	463	Missense	distal	5	no	318.747	283.361	EPSD	ICGC;COSMIC	255.132	Down-regulation
CAMK_CAMKL_MARK_MARK3_ST	P27448	MARK3	P27448-3	MARK3	S469	A468V	468	Missense	proximal	-1	no	343.219	343.860	EPSD	ICGC;COSMIC	255.132	Up-regulation
CAMK_CAMKL_MARK_MARK3_ST	P27448	MARK3	P27448-3	MARK3	S469	M471I	471	Missense	proximal	2	no	343.219	317.810	EPSD	ICGC	255.132	Down-regulation
CAMK_CAMKL_MARK_MARK3_ST	P27448	MARK3	P27448-3	MARK3	S469	P470H	470	Missense	proximal	1	no	343.219	343.235	EPSD	ICGC;COSMIC	255.132	Up-regulation
CAMK_CAMKL_MARK_MARK3_ST	P27448	MARK3	P27448-3	MARK3	S469	K463E	463	Missense	distal	-6	no	343.219	344.493	EPSD	ICGC;COSMIC	255.132	Up-regulation
CAMK_CAMKL_MARK_MARK3_ST	P27448	MARK3	P27448-3	MARK3	S476	D482Y	482	Missense	distal	6	no	355.903	352.224	EPSD	ICGC;COSMIC	255.132	Down-regulation
CAMK_CAMKL_MARK_MARK3_ST	P27448	MARK3	P27448-3	MARK3	S476	M471I	471	Missense	distal	-5	no	355.903	295.746	EPSD	ICGC	255.132	Down-regulation
CAMK_CAMKL_MARK_MARK3_ST	P27448	MARK3	P27448-3	MARK3	S476	P470H	470	Missense	distal	-6	no	355.903	358.096	EPSD	ICGC;COSMIC	255.132	Up-regulation
CAMK_CAMKL_MARK_MARK3_ST	P27448	MARK3	P27448-3	MARK3	S476	A481E	481	Missense	distal	5	no	355.903	343.773	EPSD	ICGC;COSMIC	255.132	Down-regulation
CAMK_CAMKL_MARK_MARK3_ST	P27448	MARK3	P27448-3	MARK3	S499	R504Q	504	Missense	distal	5	no	263.040	251.183	EPSD	ICGC	255.132	Loss
CAMK_CAMKL_MARK_MARK3_ST	P27448	MARK3	P27448-3	MARK3	S499	P493T	493	Missense	distal	-6	no	263.040	264.891	EPSD	ICGC;COSMIC	255.132	Up-regulation
CAMK_CAMKL_MARK_MARK3_ST	P27448	MARK3	P27448-3	MARK3	S540	A539S	539	Missense	proximal	-1	no	256.896	257.573	EPSD	ICGC	255.132	Up-regulation
CAMK_CAMKL_MARK_MARK3_ST	P27448	MARK3	P27448-3	MARK3	T564	S561I	561	Missense	distal	-3	no	326.655	301.618	EPSD	ICGC	255.132	Down-regulation
CAMK_CAMKL_MARK_MARK3_ST	P27448	MARK3	P27448-3	MARK3	T564	R562H	562	Missense	proximal	-2	no	326.655	310.855	EPSD	ICGC;COSMIC	255.132	Down-regulation
CAMK_CAMKL_MARK_MARK3_ST	P27448	MARK3	P27448-3	MARK3	T576	R573Q	573	Missense	distal	-3	no	260.044	232.094	EPSD	ICGC;COSMIC	255.132	Loss
CAMK_CAMKL_MARK_MARK3_ST	P27448	MARK3	P27448-3	MARK3	T576	R573L	573	Missense	distal	-3	no	260.044	216.641	EPSD	ICGC;COSMIC	255.132	Loss
CAMK_CAMKL_MARK_MARK3_ST	P27448	MARK3	P27448-3	MARK3	T591	S585I	585	Missense	distal	-6	no	257.916	257.451	EPSD	ICGC	255.132	Down-regulation
CAMK_CAMKL_MARK_MARK3_ST	P27448	MARK3	P27448-3	MARK3	S601	L608F	608	Missense	distal	7	no	377.882	379.530	PhosphoSitePlus;EPSD	ICGC;COSMIC	255.132	Up-regulation
CAMK_CAMKL_MARK_MARK3_ST	P27448	MARK3	P27448-3	MARK3	T602	L608F	608	Missense	distal	6	no	369.966	345.847	EPSD;PhosphoSitePlus	ICGC;COSMIC	255.132	Down-regulation
CAMK_CAMKL_MARK_MARK3_ST	P27448	MARK3	P27448-3	MARK3	S606	L608F	608	Missense	proximal	2	no	332.106	316.259	EPSD;PhosphoSitePlus	ICGC;COSMIC	255.132	Down-regulation
CK1_CK1_CK1-G_CSNK1G2_ST	Q14457	BECN1	P78368	CSNK1G2	S7	Q13R	13	Missense	distal	6	no	1.776	1.739	EPSD	ICGC;COSMIC	1.578	Down-regulation
CK1_CK1_CK1-G_CSNK1G2_ST	Q14457	BECN1	P78368	CSNK1G2	S7	M12I	12	Missense	distal	5	no	1.776	1.818	EPSD	ICGC;COSMIC	1.578	Up-regulation
CK1_CK1_CK1-G_CSNK1G2_ST	Q14457	BECN1	P78368	CSNK1G2	T11	Q13R	13	Missense	proximal	2	no	2.345	2.330	EPSD	ICGC;COSMIC	1.578	Down-regulation
CK1_CK1_CK1-G_CSNK1G2_ST	Q14457	BECN1	P78368	CSNK1G2	T11	M12I	12	Missense	proximal	1	no	2.345	2.317	EPSD	ICGC;COSMIC	1.578	Down-regulation
CK1_CK1_CK1-G_CSNK1G2_ST	Q14457	BECN1	P78368	CSNK1G2	T11	T6M	6	Missense	distal	-5	no	2.345	2.415	EPSD	ICGC;COSMIC	1.578	Up-regulation
CK1_CK1_CK1-G_CSNK1G2_ST	Q14457	BECN1	P78368	CSNK1G2	S96	A103E	103	Missense	distal	7	no	3.351	3.457	EPSD	ICGC	1.578	Up-regulation
CK1_CK1_CK1-G_CSNK1G2_ST	Q14457	BECN1	P78368	CSNK1G2	T406	D405E	405	Missense	proximal	-1	no	7.721	7.100	EPSD;PhosphoSitePlus	ICGC	1.578	Down-regulation
CK1_CK1_CK1-G_CSNK1G2_ST	Q14457	BECN1	P78368	CSNK1G2	T406	D405G	405	Missense	proximal	-1	no	7.721	7.958	EPSD;PhosphoSitePlus	ICGC;COSMIC	1.578	Up-regulation
CK1_CK1_CK1-G_CSNK1G2_ST	Q14457	BECN1	P78368	CSNK1G2	S409	I415M	415	Missense	distal	6	no	8.514	8.534	PhosphoSitePlus;EPSD	ICGC	1.578	Up-regulation
CK1_CK1_CK1-G_CSNK1G2_ST	Q14457	BECN1	P78368	CSNK1G2	S409	D405E	405	Missense	distal	-4	no	8.514	8.531	PhosphoSitePlus;EPSD	ICGC	1.578	Up-regulation
CK1_CK1_CK1-G_CSNK1G2_ST	Q14457	BECN1	P78368	CSNK1G2	S409	D405G	405	Missense	distal	-4	no	8.514	8.515	PhosphoSitePlus;EPSD	ICGC;COSMIC	1.578	Up-regulation
CK1_CK1_CK1-G_CSNK1G2_ST	P84022	SMAD3	P78368	CSNK1G2	T8	L15V	15	Missense	distal	7	no	3.665	3.548	EPSD	ICGC;COSMIC	1.578	Down-regulation
CK1_CK1_CK1-G_CSNK1G2_ST	P84022	SMAD3	P78368	CSNK1G2	T388	P393T	393	Missense	distal	5	no	3.568	3.537	EPSD	ICGC;COSMIC	1.578	Down-regulation
CK1_CK1_CK1-G_CSNK1G2_ST	O14654	IRS4	P78368	CSNK1G2	S68	V75I	75	Missense	distal	7	no	1.608	1.641	EPSD	ICGC;COSMIC	1.578	Up-regulation
CK1_CK1_CK1-G_CSNK1G2_ST	O14654	IRS4	P78368	CSNK1G2	S558	G559R	559	Missense	proximal	1	no	1.678	1.540	EPSD	ICGC;COSMIC	1.578	Loss
CK1_CK1_CK1-G_CSNK1G2_ST	O14654	IRS4	P78368	CSNK1G2	S570	S570A	570	Missense	central	0	yes	1.794	0.000	EPSD	ICGC;COSMIC	1.578	Loss
CK1_CK1_CK1-G_CSNK1G2_ST	O14654	IRS4	P78368	CSNK1G2	T643	G642E	642	Missense	proximal	-1	no	3.133	2.276	EPSD	ICGC	1.578	Down-regulation
CK1_CK1_CK1-G_CSNK1G2_ST	O14654	IRS4	P78368	CSNK1G2	S770	D763G	763	Missense	distal	-7	no	2.537	2.366	EPSD	ICGC;COSMIC	1.578	Down-regulation
CK1_CK1_CK1-G_CSNK1G2_ST	O14654	IRS4	P78368	CSNK1G2	S770	D768Y	768	Missense	proximal	-2	no	2.537	2.566	EPSD	ICGC;COSMIC	1.578	Up-regulation
CK1_CK1_CK1-G_CSNK1G2_ST	O14654	IRS4	P78368	CSNK1G2	S770	D769E	769	Missense	proximal	-1	no	2.537	1.916	EPSD	ICGC;COSMIC	1.578	Down-regulation
CK1_CK1_CK1-G_CSNK1G2_ST	O14654	IRS4	P78368	CSNK1G2	S804	S800P	800	Missense	distal	-4	no	1.640	1.678	EPSD	ICGC;COSMIC	1.578	Up-regulation
AGC_PKC_PKCd_PRKCQ_ST	O94992	HEXIM1	Q04759	PRKCQ	S268	Q264L	264	Missense	distal	-4	no	1.985	1.971	EPSD	ICGC;COSMIC	1.204	Down-regulation
AGC_PKC_PKCd_PRKCQ_ST	P35241	RDX	Q04759	PRKCQ	S249	D252E	252	Missense	distal	3	no	1.618	1.619	EPSD	ICGC	1.204	Up-regulation
AGC_PKC_PKCd_PRKCQ_ST	P35241	RDX	Q04759	PRKCQ	T564	A557E	557	Missense	distal	-7	no	1.468	1.473	PhosphoSitePlus	ICGC	1.204	Up-regulation
AGC_PKC_PKCd_PRKCQ_ST	Q92934	BAD	Q04759	PRKCQ	S74	R72S	72	Missense	proximal	-2	no	1.454	0.846	EPSD	ICGC	1.204	Loss
AGC_PKC_PKCd_PRKCQ_ST	Q92934	BAD	Q04759	PRKCQ	S74	T80K	80	Missense	distal	6	no	1.454	1.497	EPSD	ICGC	1.204	Up-regulation
AGC_PKC_PKCd_PRKCQ_ST	Q92934	BAD	Q04759	PRKCQ	S74	S74G	74	Missense	central	0	yes	1.454	0.000	EPSD	ICGC;COSMIC	1.204	Loss
AGC_PKC_PKCd_PRKCQ_ST	Q92934	BAD	Q04759	PRKCQ	S75	R72S	72	Missense	distal	-3	no	2.338	1.248	PhosphoSitePlus;EPSD	ICGC	1.204	Down-regulation
AGC_PKC_PKCd_PRKCQ_ST	Q92934	BAD	Q04759	PRKCQ	S75	T80K	80	Missense	distal	5	no	2.338	2.356	PhosphoSitePlus;EPSD	ICGC	1.204	Up-regulation
AGC_PKC_PKCd_PRKCQ_ST	Q92934	BAD	Q04759	PRKCQ	S75	S74G	74	Missense	proximal	-1	no	2.338	2.334	PhosphoSitePlus;EPSD	ICGC;COSMIC	1.204	Down-regulation
AGC_PKC_PKCd_PRKCQ_ST	Q92934	BAD	Q04759	PRKCQ	S97	S99L	99	Missense	proximal	2	no	1.818	1.796	EPSD	ICGC	1.204	Down-regulation
AGC_PKC_PKCd_PRKCQ_ST	Q92934	BAD	Q04759	PRKCQ	S97	R94W	94	Missense	distal	-3	no	1.818	0.506	EPSD	ICGC	1.204	Loss
AGC_PKC_PKCd_PRKCQ_ST	Q92934	BAD	Q04759	PRKCQ	S99	S99L	99	Missense	central	0	yes	2.414	0.000	EPSD;PhosphoSitePlus	ICGC	1.204	Loss
AGC_PKC_PKCd_PRKCQ_ST	Q92934	BAD	Q04759	PRKCQ	S99	R94W	94	Missense	distal	-5	no	2.414	2.152	EPSD;PhosphoSitePlus	ICGC	1.204	Down-regulation
AGC_PKC_PKCd_PRKCQ_ST	Q92934	BAD	Q04759	PRKCQ	S118	R112S	112	Missense	distal	-6	no	2.130	2.302	EPSD	ICGC	1.204	Up-regulation
AGC_PKC_PKCd_PRKCQ_ST	Q92934	BAD	Q04759	PRKCQ	S144	R149L	149	Missense	distal	5	no	1.214	1.184	EPSD	ICGC;COSMIC	1.204	Loss
AGC_PKC_PKCd_PRKCQ_ST	Q92934	BAD	Q04759	PRKCQ	S145	R149L	149	Missense	distal	4	no	2.381	2.203	EPSD	ICGC;COSMIC	1.204	Down-regulation
AGC_PKC_PKCd_PRKCQ_ST	Q92934	BAD	Q04759	PRKCQ	S164	S167F	167	Missense	distal	3	no	1.894	1.887	EPSD	ICGC	1.204	Down-regulation
AGC_PKC_PKCd_PRKCQ_ST	P15311	EZR	Q04759	PRKCQ	S66	L59M	59	Missense	distal	-7	no	1.743	1.737	EPSD	ICGC	1.204	Down-regulation
AGC_PKC_PKCd_PRKCQ_ST	P15311	EZR	Q04759	PRKCQ	S66	A67V	67	Missense	proximal	1	no	1.743	1.736	EPSD	ICGC	1.204	Down-regulation
AGC_PKC_PKCd_PRKCQ_ST	P15311	EZR	Q04759	PRKCQ	S66	V65G	65	Missense	proximal	-1	no	1.743	1.745	EPSD	ICGC;COSMIC	1.204	Up-regulation
AGC_PKC_PKCd_PRKCQ_ST	P15311	EZR	Q04759	PRKCQ	S249	F255L	255	Missense	distal	6	no	1.607	1.598	EPSD	ICGC;COSMIC	1.204	Down-regulation
AGC_PKC_PKCd_PRKCQ_ST	P15311	EZR	Q04759	PRKCQ	S249	D252H	252	Missense	distal	3	no	1.607	1.612	EPSD	ICGC	1.204	Up-regulation
AGC_PKC_PKCd_PRKCQ_ST	P15311	EZR	Q04759	PRKCQ	T332	E334K	334	Missense	proximal	2	no	1.880	2.088	EPSD	ICGC;COSMIC	1.204	Up-regulation
AGC_PKC_PKCd_PRKCQ_ST	P15311	EZR	Q04759	PRKCQ	S366	Q368K	368	Missense	proximal	2	no	1.178	1.333	EPSD	ICGC;COSMIC	1.204	Gain
AGC_PKC_PKCd_PRKCQ_ST	P15311	EZR	Q04759	PRKCQ	S413	Q410K	410	Missense	distal	-3	no	0.700	1.510	EPSD	ICGC	1.204	Gain
AGC_PKC_PKCd_PRKCQ_ST	P15311	EZR	Q04759	PRKCQ	T567	T567M	567	Missense	central	0	yes	1.525	0.000	PhosphoSitePlus	ICGC;COSMIC	1.204	Loss
AGC_PKC_PKCd_PRKCQ_ST	P15311	EZR	Q04759	PRKCQ	T567	Q573K	573	Missense	distal	6	no	1.525	1.551	PhosphoSitePlus	ICGC	1.204	Up-regulation
AGC_PKC_PKCd_PRKCQ_ST	Q04759	PRKCQ	Q04759	PRKCQ	S345	Q342R	342	Missense	distal	-3	no	0.280	1.508	EPSD	ICGC;COSMIC	1.204	Gain
AGC_PKC_PKCd_PRKCQ_ST	Q04759	PRKCQ	Q04759	PRKCQ	S657	R652Q	652	Missense	distal	-5	no	1.776	1.540	EPSD	ICGC;COSMIC	1.204	Down-regulation
AGC_PKC_PKCd_PRKCQ_ST	Q04759	PRKCQ	Q04759	PRKCQ	S676	A678S	678	Missense	proximal	2	no	2.038	2.019	EPSD	ICGC;COSMIC	1.204	Down-regulation
AGC_PKC_PKCd_PRKCQ_ST	Q04759	PRKCQ	Q04759	PRKCQ	S676	E671D	671	Missense	distal	-5	no	2.038	2.042	EPSD	ICGC;COSMIC	1.204	Up-regulation
AGC_PKC_PKCd_PRKCQ_ST	Q04759	PRKCQ	Q04759	PRKCQ	S676	R674Q	674	Missense	proximal	-2	no	2.038	1.382	EPSD	ICGC;COSMIC;GDSC	1.204	Down-regulation
AGC_PKC_PKCd_PRKCQ_ST	Q04759	PRKCQ	Q04759	PRKCQ	S695	E702Q	702	Missense	distal	7	no	1.753	1.732	EPSD	ICGC;COSMIC	1.204	Down-regulation
AGC_PKC_PKCd_PRKCQ_ST	Q04759	PRKCQ	Q04759	PRKCQ	S706	E702Q	702	Missense	distal	-4	no	1.770	1.782	EPSD	ICGC;COSMIC	1.204	Up-regulation
AGC_PKC_PKCd_PRKCQ_ST	P35568	IRS1	Q04759	PRKCQ	S24	K23N	23	Missense	proximal	-1	no	1.549	1.544	EPSD	ICGC;COSMIC	1.204	Down-regulation
AGC_PKC_PKCd_PRKCQ_ST	P35568	IRS1	Q04759	PRKCQ	S36	E37Q	37	Missense	proximal	1	no	1.488	1.491	EPSD	ICGC;COSMIC;CCLE	1.204	Up-regulation
AGC_PKC_PKCd_PRKCQ_ST	P35568	IRS1	Q04759	PRKCQ	S268	R265H	265	Missense	distal	-3	no	1.946	0.834	EPSD	ICGC	1.204	Loss
AGC_PKC_PKCd_PRKCQ_ST	P35568	IRS1	Q04759	PRKCQ	S268	F264L	264	Missense	distal	-4	no	1.946	1.937	EPSD	ICGC	1.204	Down-regulation
AGC_PKC_PKCd_PRKCQ_ST	P35568	IRS1	Q04759	PRKCQ	S268	S272P	272	Missense	distal	4	no	1.946	1.960	EPSD	ICGC	1.204	Up-regulation
AGC_PKC_PKCd_PRKCQ_ST	P35568	IRS1	Q04759	PRKCQ	S268	S268I	268	Missense	central	0	yes	1.946	0.000	EPSD	ICGC;COSMIC	1.204	Loss
AGC_PKC_PKCd_PRKCQ_ST	P35568	IRS1	Q04759	PRKCQ	S270	R265H	265	Missense	distal	-5	no	2.580	2.359	EPSD	ICGC	1.204	Down-regulation
AGC_PKC_PKCd_PRKCQ_ST	P35568	IRS1	Q04759	PRKCQ	S270	F264L	264	Missense	distal	-6	no	2.580	2.624	EPSD	ICGC	1.204	Up-regulation
AGC_PKC_PKCd_PRKCQ_ST	P35568	IRS1	Q04759	PRKCQ	S270	S272P	272	Missense	proximal	2	no	2.580	2.639	EPSD	ICGC	1.204	Up-regulation
AGC_PKC_PKCd_PRKCQ_ST	P35568	IRS1	Q04759	PRKCQ	S270	S268I	268	Missense	proximal	-2	no	2.580	2.456	EPSD	ICGC;COSMIC	1.204	Down-regulation
AGC_PKC_PKCd_PRKCQ_ST	P35568	IRS1	Q04759	PRKCQ	S272	R265H	265	Missense	distal	-7	no	1.399	1.419	EPSD	ICGC	1.204	Up-regulation
AGC_PKC_PKCd_PRKCQ_ST	P35568	IRS1	Q04759	PRKCQ	S272	S272P	272	Missense	central	0	yes	1.399	0.000	EPSD	ICGC	1.204	Loss
AGC_PKC_PKCd_PRKCQ_ST	P35568	IRS1	Q04759	PRKCQ	S272	N278T	278	Missense	distal	6	no	1.399	1.385	EPSD	ICGC	1.204	Down-regulation
AGC_PKC_PKCd_PRKCQ_ST	P35568	IRS1	Q04759	PRKCQ	S272	S268I	268	Missense	distal	-4	no	1.399	1.373	EPSD	ICGC;COSMIC	1.204	Down-regulation
AGC_PKC_PKCd_PRKCQ_ST	P35568	IRS1	Q04759	PRKCQ	S303	T300P	300	Missense	distal	-3	no	1.174	1.421	EPSD	ICGC;COSMIC;GDSC	1.204	Gain
AGC_PKC_PKCd_PRKCQ_ST	P35568	IRS1	Q04759	PRKCQ	T305	T300P	300	Missense	distal	-5	no	1.234	1.306	EPSD	ICGC;COSMIC;GDSC	1.204	Up-regulation
AGC_PKC_PKCd_PRKCQ_ST	P35568	IRS1	Q04759	PRKCQ	S307	T300P	300	Missense	distal	-7	no	1.791	1.786	EPSD	ICGC;COSMIC;GDSC	1.204	Down-regulation
AGC_PKC_PKCd_PRKCQ_ST	P35568	IRS1	Q04759	PRKCQ	S323	G319R	319	Missense	distal	-4	no	1.628	1.687	EPSD	ICGC;COSMIC	1.204	Up-regulation
AGC_PKC_PKCd_PRKCQ_ST	P35568	IRS1	Q04759	PRKCQ	S330	G332S	332	Missense	proximal	2	no	1.440	1.463	EPSD	ICGC;COSMIC	1.204	Up-regulation
AGC_PKC_PKCd_PRKCQ_ST	P35568	IRS1	Q04759	PRKCQ	S341	S345N	345	Missense	distal	4	no	2.052	2.043	EPSD	ICGC	1.204	Down-regulation
AGC_PKC_PKCd_PRKCQ_ST	P35568	IRS1	Q04759	PRKCQ	S362	H355Q	355	Missense	distal	-7	no	1.815	1.816	EPSD	ICGC	1.204	Up-regulation
AGC_PKC_PKCd_PRKCQ_ST	P35568	IRS1	Q04759	PRKCQ	S362	L369H	369	Missense	distal	7	no	1.815	1.797	EPSD	ICGC;COSMIC	1.204	Down-regulation
AGC_PKC_PKCd_PRKCQ_ST	P35568	IRS1	Q04759	PRKCQ	S383	P389T	389	Missense	distal	6	no	1.259	1.237	EPSD	ICGC	1.204	Down-regulation
AGC_PKC_PKCd_PRKCQ_ST	P35568	IRS1	Q04759	PRKCQ	S412	S412P	412	Missense	central	0	yes	1.494	0.000	EPSD	ICGC	1.204	Loss
AGC_PKC_PKCd_PRKCQ_ST	P35568	IRS1	Q04759	PRKCQ	S412	A414D	414	Missense	proximal	2	no	1.494	1.440	EPSD	ICGC	1.204	Down-regulation
AGC_PKC_PKCd_PRKCQ_ST	P35568	IRS1	Q04759	PRKCQ	S412	R411L	411	Missense	proximal	-1	no	1.494	1.481	EPSD	ICGC;COSMIC	1.204	Down-regulation
AGC_PKC_PKCd_PRKCQ_ST	P35568	IRS1	Q04759	PRKCQ	S412	R410W	410	Missense	proximal	-2	no	1.494	0.780	EPSD	ICGC	1.204	Loss
AGC_PKC_PKCd_PRKCQ_ST	P35568	IRS1	Q04759	PRKCQ	S413	S412P	412	Missense	proximal	-1	no	2.138	2.136	EPSD	ICGC	1.204	Down-regulation
AGC_PKC_PKCd_PRKCQ_ST	P35568	IRS1	Q04759	PRKCQ	S413	A414D	414	Missense	proximal	1	no	2.138	2.131	EPSD	ICGC	1.204	Down-regulation
AGC_PKC_PKCd_PRKCQ_ST	P35568	IRS1	Q04759	PRKCQ	S413	R411L	411	Missense	proximal	-2	no	2.138	1.387	EPSD	ICGC;COSMIC	1.204	Down-regulation
AGC_PKC_PKCd_PRKCQ_ST	P35568	IRS1	Q04759	PRKCQ	S413	R410W	410	Missense	distal	-3	no	2.138	0.826	EPSD	ICGC	1.204	Loss
AGC_PKC_PKCd_PRKCQ_ST	P35568	IRS1	Q04759	PRKCQ	S415	S412P	412	Missense	distal	-3	no	1.125	1.229	EPSD	ICGC	1.204	Gain
AGC_PKC_PKCd_PRKCQ_ST	P35568	IRS1	Q04759	PRKCQ	S441	D437Y	437	Missense	distal	-4	no	1.831	1.836	EPSD	ICGC;COSMIC	1.204	Up-regulation
AGC_PKC_PKCd_PRKCQ_ST	P35568	IRS1	Q04759	PRKCQ	T525	S531Y	531	Missense	distal	6	no	1.703	1.689	EPSD	ICGC	1.204	Down-regulation
AGC_PKC_PKCd_PRKCQ_ST	P35568	IRS1	Q04759	PRKCQ	S527	S531Y	531	Missense	distal	4	no	1.950	1.933	EPSD	ICGC	1.204	Down-regulation
AGC_PKC_PKCd_PRKCQ_ST	P35568	IRS1	Q04759	PRKCQ	S574	R572M	572	Missense	proximal	-2	no	1.323	0.702	EPSD	ICGC;COSMIC	1.204	Loss
AGC_PKC_PKCd_PRKCQ_ST	P35568	IRS1	Q04759	PRKCQ	S574	P578H	578	Missense	distal	4	no	1.323	1.305	EPSD	ICGC	1.204	Down-regulation
AGC_PKC_PKCd_PRKCQ_ST	P35568	IRS1	Q04759	PRKCQ	S574	H571N	571	Missense	distal	-3	no	1.323	1.255	EPSD	ICGC	1.204	Down-regulation
AGC_PKC_PKCd_PRKCQ_ST	P35568	IRS1	Q04759	PRKCQ	S574	A575T	575	Missense	proximal	1	no	1.323	1.319	EPSD	ICGC;COSMIC	1.204	Down-regulation
AGC_PKC_PKCd_PRKCQ_ST	P35568	IRS1	Q04759	PRKCQ	S603	R600H	600	Missense	distal	-3	no	2.139	1.026	EPSD	ICGC;COSMIC	1.204	Loss
AGC_PKC_PKCd_PRKCQ_ST	P35568	IRS1	Q04759	PRKCQ	S629	P634S	634	Missense	distal	5	no	2.138	2.135	EPSD	ICGC;COSMIC	1.204	Down-regulation
AGC_PKC_PKCd_PRKCQ_ST	P35568	IRS1	Q04759	PRKCQ	S629	Y632C	632	Missense	distal	3	no	2.138	2.136	EPSD	ICGC;COSMIC	1.204	Down-regulation
AGC_PKC_PKCd_PRKCQ_ST	P35568	IRS1	Q04759	PRKCQ	S629	K627N	627	Missense	proximal	-2	no	2.138	1.721	EPSD	ICGC;COSMIC	1.204	Down-regulation
AGC_PKC_PKCd_PRKCQ_ST	P35568	IRS1	Q04759	PRKCQ	S641	P634S	634	Missense	distal	-7	no	1.435	1.438	EPSD	ICGC;COSMIC	1.204	Up-regulation
AGC_PKC_PKCd_PRKCQ_ST	P35568	IRS1	Q04759	PRKCQ	S792	T793A	793	Missense	proximal	1	no	1.315	1.319	EPSD	ICGC;COSMIC	1.204	Up-regulation
AGC_PKC_PKCd_PRKCQ_ST	P35568	IRS1	Q04759	PRKCQ	S792	T793S	793	Missense	proximal	1	no	1.315	1.317	EPSD	ICGC;COSMIC	1.204	Up-regulation
AGC_PKC_PKCd_PRKCQ_ST	P35568	IRS1	Q04759	PRKCQ	S792	R790H	790	Missense	proximal	-2	no	1.315	0.712	EPSD	ICGC	1.204	Loss
AGC_PKC_PKCd_PRKCQ_ST	P35568	IRS1	Q04759	PRKCQ	S862	K867T	867	Missense	distal	5	no	1.309	1.290	EPSD	ICGC	1.204	Down-regulation
AGC_PKC_PKCd_PRKCQ_ST	P35568	IRS1	Q04759	PRKCQ	S862	P866T	866	Missense	distal	4	no	1.309	1.270	EPSD	ICGC	1.204	Down-regulation
AGC_PKC_PKCd_PRKCQ_ST	P35568	IRS1	Q04759	PRKCQ	S869	K867T	867	Missense	proximal	-2	no	1.781	1.339	EPSD	ICGC	1.204	Down-regulation
AGC_PKC_PKCd_PRKCQ_ST	P35568	IRS1	Q04759	PRKCQ	S869	R873P	873	Missense	distal	4	no	1.781	1.648	EPSD	ICGC	1.204	Down-regulation
AGC_PKC_PKCd_PRKCQ_ST	P35568	IRS1	Q04759	PRKCQ	S869	P866T	866	Missense	distal	-3	no	1.781	1.534	EPSD	ICGC	1.204	Down-regulation
AGC_PKC_PKCd_PRKCQ_ST	P35568	IRS1	Q04759	PRKCQ	S869	A874G	874	Missense	distal	5	no	1.781	1.772	EPSD	ICGC;COSMIC	1.204	Down-regulation
AGC_PKC_PKCd_PRKCQ_ST	P35568	IRS1	Q04759	PRKCQ	S974	G971R	971	Missense	distal	-3	no	0.633	1.951	EPSD	ICGC;COSMIC	1.204	Gain
AGC_PKC_PKCd_PRKCQ_ST	P35568	IRS1	Q04759	PRKCQ	S1000	D1003N	1003	Missense	distal	3	no	1.727	1.732	EPSD	ICGC;COSMIC	1.204	Up-regulation
AGC_PKC_PKCd_PRKCQ_ST	P35568	IRS1	Q04759	PRKCQ	S1100	S1106L	1106	Missense	distal	6	no	2.727	2.706	EPSD	ICGC;COSMIC	1.204	Down-regulation
AGC_PKC_PKCd_PRKCQ_ST	P35568	IRS1	Q04759	PRKCQ	S1101	S1106L	1106	Missense	distal	5	no	2.483	2.477	PhosphoSitePlus	ICGC;COSMIC	1.204	Down-regulation
AGC_PKC_PKCd_PRKCQ_ST	P35568	IRS1	Q04759	PRKCQ	S1142	D1137N	1137	Missense	distal	-5	no	2.325	2.369	EPSD	ICGC	1.204	Up-regulation
AGC_PKC_PKCd_PRKCQ_ST	P35568	IRS1	Q04759	PRKCQ	S1143	D1137N	1137	Missense	distal	-6	no	2.131	2.095	EPSD	ICGC	1.204	Down-regulation
AGC_PKC_PKCd_PRKCQ_ST	P35568	IRS1	Q04759	PRKCQ	S1213	L1211R	1211	Missense	proximal	-2	no	0.550	1.300	EPSD	ICGC;COSMIC	1.204	Gain
AGC_PKC_PKCd_PRKCQ_ST	P35568	IRS1	Q04759	PRKCQ	S1222	R1220H	1220	Missense	proximal	-2	no	1.283	0.680	EPSD	ICGC;COSMIC	1.204	Loss
AGC_PKC_PKCd_PRKCQ_ST	P35568	IRS1	Q04759	PRKCQ	S1222	T1219P	1219	Missense	distal	-3	no	1.283	1.530	EPSD	ICGC;COSMIC;GDSC	1.204	Up-regulation
AGC_PKC_PKCd_PRKCQ_ST	P35568	IRS1	Q04759	PRKCQ	S1223	R1220H	1220	Missense	distal	-3	no	2.309	1.196	EPSD	ICGC;COSMIC	1.204	Loss
AGC_PKC_PKCd_PRKCQ_ST	P35568	IRS1	Q04759	PRKCQ	S1223	T1219P	1219	Missense	distal	-4	no	2.309	2.331	EPSD	ICGC;COSMIC;GDSC	1.204	Up-regulation
AGC_PKC_PKCd_PRKCQ_ST	P35236	PTPN7	Q04759	PRKCQ	S93	Q88R	88	Missense	distal	-5	no	1.001	1.237	EPSD	ICGC;COSMIC	1.204	Gain
AGC_PKC_PKCd_PRKCQ_ST	Q3V6T2	CCDC88A	Q04759	PRKCQ	S245	L249P	249	Missense	distal	4	no	2.334	2.379	EPSD	ICGC	1.204	Up-regulation
AGC_PKC_PKCd_PRKCQ_ST	Q3V6T2	CCDC88A	Q04759	PRKCQ	S245	L249M	249	Missense	distal	4	no	2.334	2.365	EPSD	ICGC;COSMIC	1.204	Up-regulation
AGC_PKC_PKCd_PRKCQ_ST	Q3V6T2	CCDC88A	Q04759	PRKCQ	S245	S250W	250	Missense	distal	5	no	2.334	2.329	EPSD	ICGC;COSMIC	1.204	Down-regulation
AGC_PKC_PKCd_PRKCQ_ST	Q3V6T2	CCDC88A	Q04759	PRKCQ	S1462	S1461C	1461	Missense	proximal	-1	no	1.420	1.416	EPSD	ICGC	1.204	Down-regulation
AGC_PKC_PKCd_PRKCQ_ST	Q3V6T2	CCDC88A	Q04759	PRKCQ	S1796	S1790Y	1790	Missense	distal	-6	no	1.239	1.290	EPSD	ICGC;COSMIC	1.204	Up-regulation
AGC_PKC_PKCd_PRKCQ_ST	O95267	RASGRP1	Q04759	PRKCQ	T184	W179R	179	Missense	distal	-5	no	1.751	2.012	PhosphoSitePlus	ICGC;COSMIC	1.204	Up-regulation
AGC_PKC_PKCd_PRKCQ_ST	O95267	RASGRP1	Q04759	PRKCQ	T184	D178N	178	Missense	distal	-6	no	1.751	1.714	PhosphoSitePlus	ICGC	1.204	Down-regulation
AGC_PKC_PKCd_PRKCQ_ST	O95267	RASGRP1	Q04759	PRKCQ	T184	R186M	186	Missense	proximal	2	no	1.751	1.528	PhosphoSitePlus	ICGC;COSMIC	1.204	Down-regulation
AGC_PKC_PKCd_PRKCQ_ST	O95267	RASGRP1	Q04759	PRKCQ	S732	W727L	727	Missense	distal	-5	no	1.220	1.206	EPSD	ICGC;COSMIC	1.204	Down-regulation
AGC_PKC_PKCd_PRKCQ_ST	O95267	RASGRP1	Q04759	PRKCQ	S732	K735Q	735	Missense	distal	3	no	1.220	1.210	EPSD	ICGC;COSMIC	1.204	Down-regulation
AGC_PKC_PKCd_PRKCQ_ST	O95267	RASGRP1	Q04759	PRKCQ	S732	S732P	732	Missense	central	0	yes	1.220	0.000	EPSD	ICGC;COSMIC	1.204	Loss
AGC_PKC_PKCd_PRKCQ_ST	Q9BXL7	CARD11	Q04759	PRKCQ	S116	G123S	123	Missense	distal	7	no	2.631	2.609	EPSD	ICGC;COSMIC	1.204	Down-regulation
AGC_PKC_PKCd_PRKCQ_ST	Q9BXL7	CARD11	Q04759	PRKCQ	S116	I118V	118	Missense	proximal	2	no	2.631	2.602	EPSD	ICGC;COSMIC	1.204	Down-regulation
AGC_PKC_PKCd_PRKCQ_ST	Q9BXL7	CARD11	Q04759	PRKCQ	S116	S116A	116	Missense	central	0	yes	2.631	0.000	EPSD	ICGC;COSMIC	1.204	Loss
AGC_PKC_PKCd_PRKCQ_ST	Q9BXL7	CARD11	Q04759	PRKCQ	S116	P111S	111	Missense	distal	-5	no	2.631	2.634	EPSD	ICGC;COSMIC	1.204	Up-regulation
AGC_PKC_PKCd_PRKCQ_ST	Q9BXL7	CARD11	Q04759	PRKCQ	S116	F115I	115	Missense	proximal	-1	no	2.631	2.630	EPSD	ICGC;COSMIC	1.204	Down-regulation
AGC_PKC_PKCd_PRKCQ_ST	Q9BXL7	CARD11	Q04759	PRKCQ	S439	S439A	439	Missense	central	0	yes	2.329	0.000	EPSD	ICGC;COSMIC	1.204	Loss
AGC_PKC_PKCd_PRKCQ_ST	Q9BXL7	CARD11	Q04759	PRKCQ	S439	S433G	433	Missense	distal	-6	no	2.329	2.404	EPSD	ICGC;COSMIC	1.204	Up-regulation
AGC_PKC_PKCd_PRKCQ_ST	Q9BXL7	CARD11	Q04759	PRKCQ	S439	D446E	446	Missense	distal	7	no	2.329	2.324	EPSD	ICGC	1.204	Down-regulation
AGC_PKC_PKCd_PRKCQ_ST	Q9BXL7	CARD11	Q04759	PRKCQ	S439	D446N	446	Missense	distal	7	no	2.329	2.312	EPSD	ICGC	1.204	Down-regulation
AGC_PKC_PKCd_PRKCQ_ST	Q9BXL7	CARD11	Q04759	PRKCQ	S512	S512P	512	Missense	central	0	yes	1.722	0.000	EPSD	ICGC;COSMIC	1.204	Loss
AGC_PKC_PKCd_PRKCQ_ST	Q9BXL7	CARD11	Q04759	PRKCQ	S512	T519K	519	Missense	distal	7	no	1.722	1.669	EPSD	ICGC	1.204	Down-regulation
AGC_PKC_PKCd_PRKCQ_ST	Q9BXL7	CARD11	Q04759	PRKCQ	S512	Q508H	508	Missense	distal	-4	no	1.722	1.720	EPSD	ICGC;COSMIC	1.204	Down-regulation
AGC_PKC_PKCd_PRKCQ_ST	Q9BXL7	CARD11	Q04759	PRKCQ	S520	Q523K	523	Missense	distal	3	no	2.190	2.199	EPSD	ICGC;COSMIC	1.204	Up-regulation
AGC_PKC_PKCd_PRKCQ_ST	Q9BXL7	CARD11	Q04759	PRKCQ	S520	T519K	519	Missense	proximal	-1	no	2.190	2.197	EPSD	ICGC	1.204	Up-regulation
AGC_PKC_PKCd_PRKCQ_ST	Q9BXL7	CARD11	Q04759	PRKCQ	S520	G526W	526	Missense	distal	6	no	2.190	2.195	EPSD	ICGC;COSMIC	1.204	Up-regulation
AGC_PKC_PKCd_PRKCQ_ST	Q9BXL7	CARD11	Q04759	PRKCQ	S558	A565S	565	Missense	distal	7	no	2.001	2.011	EPSD	ICGC;COSMIC	1.204	Up-regulation
AGC_PKC_PKCd_PRKCQ_ST	Q9BXL7	CARD11	Q04759	PRKCQ	S558	Q552K	552	Missense	distal	-6	no	2.001	1.900	EPSD	ICGC	1.204	Down-regulation
AGC_PKC_PKCd_PRKCQ_ST	Q9BXL7	CARD11	Q04759	PRKCQ	S558	P553L	553	Missense	distal	-5	no	2.001	1.918	EPSD	ICGC	1.204	Down-regulation
AGC_PKC_PKCd_PRKCQ_ST	Q9BXL7	CARD11	Q04759	PRKCQ	S559	A565S	565	Missense	distal	6	no	1.890	1.896	PhosphoSitePlus	ICGC;COSMIC	1.204	Up-regulation
AGC_PKC_PKCd_PRKCQ_ST	Q9BXL7	CARD11	Q04759	PRKCQ	S559	Q552K	552	Missense	distal	-7	no	1.890	1.877	PhosphoSitePlus	ICGC	1.204	Down-regulation
AGC_PKC_PKCd_PRKCQ_ST	Q9BXL7	CARD11	Q04759	PRKCQ	S559	P553L	553	Missense	distal	-6	no	1.890	1.965	PhosphoSitePlus	ICGC	1.204	Up-regulation
AGC_PKC_PKCd_PRKCQ_ST	Q9BXL7	CARD11	Q04759	PRKCQ	S644	N637K	637	Missense	distal	-7	no	2.782	2.769	EPSD	ICGC	1.204	Down-regulation
AGC_PKC_PKCd_PRKCQ_ST	Q9BXL7	CARD11	Q04759	PRKCQ	S644	R650W	650	Missense	distal	6	no	2.782	2.735	EPSD	ICGC;COSMIC;GDSC;CCLE	1.204	Down-regulation
AGC_PKC_PKCd_PRKCQ_ST	Q9BXL7	CARD11	Q04759	PRKCQ	S652	V659M	659	Missense	distal	7	no	1.778	1.741	EPSD	ICGC;COSMIC	1.204	Down-regulation
AGC_PKC_PKCd_PRKCQ_ST	Q9BXL7	CARD11	Q04759	PRKCQ	S652	R650W	650	Missense	proximal	-2	no	1.778	1.064	EPSD	ICGC;COSMIC;GDSC;CCLE	1.204	Loss
AGC_PKC_PKCd_PRKCQ_ST	Q9BXL7	CARD11	Q04759	PRKCQ	S886	L889F	889	Missense	distal	3	no	1.869	1.873	EPSD	ICGC	1.204	Up-regulation
AGC_PKC_PKCd_PRKCQ_ST	Q9BXL7	CARD11	Q04759	PRKCQ	S923	E917V	917	Missense	distal	-6	no	2.375	2.392	EPSD	ICGC;COSMIC	1.204	Up-regulation
AGC_PKC_PKCd_PRKCQ_ST	P10588	NR2F6	Q04759	PRKCQ	S32	E29K	29	Missense	distal	-3	no	0.283	1.299	EPSD	ICGC;COSMIC	1.204	Gain
AGC_PKC_PKCd_PRKCQ_ST	P10588	NR2F6	Q04759	PRKCQ	S83	R86L	86	Missense	distal	3	no	1.324	1.301	PhosphoSitePlus	ICGC;COSMIC	1.204	Down-regulation
AGC_PKC_PKCd_PRKCQ_ST	P10588	NR2F6	Q04759	PRKCQ	S89	T91P	91	Missense	proximal	2	no	2.271	2.335	EPSD	ICGC;COSMIC	1.204	Up-regulation
AGC_PKC_PKCd_PRKCQ_ST	P10588	NR2F6	Q04759	PRKCQ	S89	R86L	86	Missense	distal	-3	no	2.271	0.922	EPSD	ICGC;COSMIC	1.204	Loss
AGC_PKC_PKCd_PRKCQ_ST	P10588	NR2F6	Q04759	PRKCQ	S345	Q342R	342	Missense	distal	-3	no	1.067	2.296	EPSD	ICGC;COSMIC	1.204	Gain
AGC_PKC_PKCd_PRKCQ_ST	P01116	KRAS	Q04759	PRKCQ	S172	K170N	170	Missense	proximal	-2	no	2.221	1.804	EPSD	ICGC;COSMIC	1.204	Down-regulation
AGC_PKC_PKCd_PRKCQ_ST	P01116	KRAS	Q04759	PRKCQ	S172	K176R	176	Missense	distal	4	no	2.221	2.283	EPSD	ICGC;COSMIC	1.204	Up-regulation
AGC_PKC_PKCd_PRKCQ_ST	P26038	MSN	Q04759	PRKCQ	S6	T4M	4	Missense	proximal	-2	no	1.727	1.792	EPSD	ICGC;COSMIC	1.204	Up-regulation
AGC_PKC_PKCd_PRKCQ_ST	P26038	MSN	Q04759	PRKCQ	S6	V7L	7	Missense	proximal	1	no	1.727	1.729	EPSD	ICGC;COSMIC	1.204	Up-regulation
AGC_PKC_PKCd_PRKCQ_ST	P26038	MSN	Q04759	PRKCQ	S74	R81H	81	Missense	distal	7	no	2.000	2.093	EPSD	ICGC;COSMIC	1.204	Up-regulation
AGC_PKC_PKCd_PRKCQ_ST	P26038	MSN	Q04759	PRKCQ	S74	K79N	79	Missense	distal	5	no	2.000	1.986	EPSD	ICGC;COSMIC	1.204	Down-regulation
AGC_PKC_PKCd_PRKCQ_ST	P26038	MSN	Q04759	PRKCQ	S249	W242L	242	Missense	distal	-7	no	1.577	1.579	EPSD	ICGC	1.204	Up-regulation
AGC_PKC_PKCd_PRKCQ_ST	P26038	MSN	Q04759	PRKCQ	S249	D252N	252	Missense	distal	3	no	1.577	1.582	EPSD	ICGC;COSMIC	1.204	Up-regulation
AGC_PKC_PKCd_PRKCQ_ST	P26038	MSN	Q04759	PRKCQ	S384	R379W	379	Missense	distal	-5	no	2.355	2.093	EPSD	ICGC;COSMIC	1.204	Down-regulation
AGC_PKC_PKCd_PRKCQ_ST	P26038	MSN	Q04759	PRKCQ	S384	Q383H	383	Missense	proximal	-1	no	2.355	2.354	EPSD	ICGC;COSMIC	1.204	Down-regulation
AGC_PKC_PKCd_PRKCQ_ST	P26038	MSN	Q04759	PRKCQ	S384	R379Q	379	Missense	distal	-5	no	2.355	2.119	EPSD	ICGC;COSMIC	1.204	Down-regulation
AGC_PKC_PKCd_PRKCQ_ST	P26038	MSN	Q04759	PRKCQ	S384	K388R	388	Missense	distal	4	no	2.355	2.417	EPSD	ICGC;COSMIC	1.204	Up-regulation
AGC_PKC_PKCd_PRKCQ_ST	P26038	MSN	Q04759	PRKCQ	S384	E385K	385	Missense	proximal	1	no	2.355	2.364	EPSD	ICGC;COSMIC;GDSC;CCLE	1.204	Up-regulation
AGC_PKC_PKCd_PRKCQ_ST	P26038	MSN	Q04759	PRKCQ	S440	R435L	435	Missense	distal	-5	no	1.649	1.374	EPSD	ICGC;COSMIC;GDSC;CCLE	1.204	Down-regulation
AGC_PKC_PKCd_PRKCQ_ST	P26038	MSN	Q04759	PRKCQ	S504	D497Y	497	Missense	distal	-7	no	1.474	1.470	EPSD	ICGC	1.204	Down-regulation
AGC_PKC_PKCd_PRKCQ_ST	P26038	MSN	Q04759	PRKCQ	S536	M543I	543	Missense	distal	7	no	1.722	1.747	EPSD	ICGC	1.204	Up-regulation
AGC_PKC_PKCd_PRKCQ_ST	P26038	MSN	Q04759	PRKCQ	T558	D554N	554	Missense	distal	-4	no	1.471	1.479	PhosphoSitePlus	ICGC;COSMIC	1.204	Up-regulation
AGC_PKC_PKCd_PRKCQ_ST	P26038	MSN	Q04759	PRKCQ	T558	T558I	558	Missense	central	0	yes	1.471	0.000	PhosphoSitePlus	ICGC;COSMIC	1.204	Loss
AGC_PKC_PKCd_PRKCQ_ST	O43516	WIPF1	Q04759	PRKCQ	S137	P140H	140	Missense	distal	3	no	2.250	2.247	EPSD	ICGC;COSMIC	1.204	Down-regulation
AGC_PKC_PKCd_PRKCQ_ST	O43516	WIPF1	Q04759	PRKCQ	S142	S145G	145	Missense	distal	3	no	1.664	1.654	EPSD	ICGC;COSMIC;GDSC;CCLE	1.204	Down-regulation
AGC_PKC_PKCd_PRKCQ_ST	O43516	WIPF1	Q04759	PRKCQ	S142	P140H	140	Missense	proximal	-2	no	1.664	1.597	EPSD	ICGC;COSMIC	1.204	Down-regulation
AGC_PKC_PKCd_PRKCQ_ST	O43516	WIPF1	Q04759	PRKCQ	S203	G208R	208	Missense	distal	5	no	1.566	1.597	EPSD	ICGC;COSMIC	1.204	Up-regulation
AGC_PKC_PKCd_PRKCQ_ST	O43516	WIPF1	Q04759	PRKCQ	S203	P198L	198	Missense	distal	-5	no	1.566	1.483	EPSD	ICGC	1.204	Down-regulation
AGC_PKC_PKCd_PRKCQ_ST	O43516	WIPF1	Q04759	PRKCQ	S203	S203F	203	Missense	central	0	yes	1.566	0.000	EPSD	ICGC;COSMIC	1.204	Loss
AGC_PKC_PKCd_PRKCQ_ST	O43516	WIPF1	Q04759	PRKCQ	S203	P207S	207	Missense	distal	4	no	1.566	1.552	EPSD	ICGC;COSMIC	1.204	Down-regulation
AGC_PKC_PKCd_PRKCQ_ST	O43516	WIPF1	Q04759	PRKCQ	S214	P217T	217	Missense	distal	3	no	1.518	1.511	EPSD	ICGC;COSMIC	1.204	Down-regulation
AGC_PKC_PKCd_PRKCQ_ST	O43516	WIPF1	Q04759	PRKCQ	S214	G208R	208	Missense	distal	-6	no	1.518	1.271	EPSD	ICGC;COSMIC	1.204	Down-regulation
AGC_PKC_PKCd_PRKCQ_ST	O43516	WIPF1	Q04759	PRKCQ	S214	R211M	211	Missense	distal	-3	no	1.518	0.361	EPSD	ICGC;COSMIC	1.204	Loss
AGC_PKC_PKCd_PRKCQ_ST	O43516	WIPF1	Q04759	PRKCQ	S214	P207S	207	Missense	distal	-7	no	1.518	1.521	EPSD	ICGC;COSMIC	1.204	Up-regulation
AGC_PKC_PKCd_PRKCQ_ST	O43516	WIPF1	Q04759	PRKCQ	S214	P220H	220	Missense	distal	6	no	1.518	1.511	EPSD	ICGC;COSMIC	1.204	Down-regulation
AGC_PKC_PKCd_PRKCQ_ST	O43516	WIPF1	Q04759	PRKCQ	S241	P239S	239	Missense	proximal	-2	no	1.276	1.203	EPSD	ICGC	1.204	Loss
AGC_PKC_PKCd_PRKCQ_ST	O43516	WIPF1	Q04759	PRKCQ	S301	P298L	298	Missense	distal	-3	no	1.451	1.087	EPSD	ICGC;COSMIC	1.204	Loss
AGC_PKC_PKCd_PRKCQ_ST	O43516	WIPF1	Q04759	PRKCQ	S301	P295H	295	Missense	distal	-6	no	1.451	1.474	EPSD	ICGC;COSMIC	1.204	Up-regulation
AGC_PKC_PKCd_PRKCQ_ST	O43516	WIPF1	Q04759	PRKCQ	S301	R299L	299	Missense	proximal	-2	no	1.451	0.700	EPSD	ICGC;COSMIC	1.204	Loss
AGC_PKC_PKCd_PRKCQ_ST	O43516	WIPF1	Q04759	PRKCQ	S340	T345K	345	Missense	distal	5	no	1.634	1.652	EPSD	ICGC;COSMIC	1.204	Up-regulation
AGC_PKC_PKCd_PRKCQ_ST	O43516	WIPF1	Q04759	PRKCQ	S340	P347S	347	Missense	distal	7	no	1.634	1.639	EPSD	ICGC	1.204	Up-regulation
AGC_PKC_PKCd_PRKCQ_ST	O43516	WIPF1	Q04759	PRKCQ	S340	P347L	347	Missense	distal	7	no	1.634	1.661	EPSD	ICGC;COSMIC	1.204	Up-regulation
AGC_PKC_PKCd_PRKCQ_ST	O43516	WIPF1	Q04759	PRKCQ	S390	A397S	397	Missense	distal	7	no	1.714	1.724	EPSD	ICGC	1.204	Up-regulation
AGC_PKC_PKCd_PRKCQ_ST	O43516	WIPF1	Q04759	PRKCQ	S390	A394V	394	Missense	distal	4	no	1.714	1.667	EPSD	ICGC;GDSC;CCLE	1.204	Down-regulation
AGC_PKC_PKCd_PRKCQ_ST	O43516	WIPF1	Q04759	PRKCQ	S390	R393Q	393	Missense	distal	3	no	1.714	1.695	EPSD	ICGC;COSMIC	1.204	Down-regulation
AGC_PKC_PKCd_PRKCQ_ST	O43516	WIPF1	Q04759	PRKCQ	S390	R393L	393	Missense	distal	3	no	1.714	1.691	EPSD	ICGC;COSMIC	1.204	Down-regulation
AGC_PKC_PKCd_PRKCQ_ST	O43516	WIPF1	Q04759	PRKCQ	S424	D421H	421	Missense	distal	-3	no	1.282	1.570	EPSD	ICGC;COSMIC	1.204	Up-regulation
AGC_PKC_PKCd_PRKCQ_ST	O43516	WIPF1	Q04759	PRKCQ	S424	P430L	430	Missense	distal	6	no	1.282	1.266	EPSD	ICGC;COSMIC	1.204	Down-regulation
AGC_PKC_PKCd_PRKCQ_ST	O43516	WIPF1	Q04759	PRKCQ	S424	R422W	422	Missense	proximal	-2	no	1.282	0.568	EPSD	ICGC;COSMIC	1.204	Loss
AGC_PKC_PKCd_PRKCQ_ST	O43516	WIPF1	Q04759	PRKCQ	S424	D421G	421	Missense	distal	-3	no	1.282	1.365	EPSD	ICGC;COSMIC	1.204	Up-regulation
AGC_PKC_PKCd_PRKCQ_ST	O43516	WIPF1	Q04759	PRKCQ	S434	R438I	438	Missense	distal	4	no	1.313	1.141	EPSD	ICGC;COSMIC	1.204	Loss
AGC_PKC_PKCd_PRKCQ_ST	O43516	WIPF1	Q04759	PRKCQ	S434	P430L	430	Missense	distal	-4	no	1.313	1.295	EPSD	ICGC;COSMIC	1.204	Down-regulation
AGC_PKC_PKCd_PRKCQ_ST	O43516	WIPF1	Q04759	PRKCQ	S436	R438I	438	Missense	proximal	2	no	1.374	1.108	EPSD	ICGC;COSMIC	1.204	Loss
AGC_PKC_PKCd_PRKCQ_ST	O43516	WIPF1	Q04759	PRKCQ	S436	P430L	430	Missense	distal	-6	no	1.374	1.449	EPSD	ICGC;COSMIC	1.204	Up-regulation
AGC_PKC_PKCd_PRKCQ_ST	O43516	WIPF1	Q04759	PRKCQ	S436	D443Y	443	Missense	distal	7	no	1.374	1.362	EPSD	ICGC;COSMIC	1.204	Down-regulation
AGC_PKC_PKCd_PRKCQ_ST	O43516	WIPF1	Q04759	PRKCQ	S488	R491I	491	Missense	distal	3	no	2.044	2.022	PhosphoSitePlus	ICGC;COSMIC	1.204	Down-regulation
AGC_PKC_PKCd_PRKCQ_ST	O43516	WIPF1	Q04759	PRKCQ	S488	A495D	495	Missense	distal	7	no	2.044	2.077	PhosphoSitePlus	ICGC	1.204	Up-regulation
AGC_PKC_PKCd_PRKCQ_ST	Q9Y4G8	RAPGEF2	Q04759	PRKCQ	S478	G484C	484	Missense	distal	6	no	1.434	1.436	EPSD	ICGC	1.204	Up-regulation
AGC_PKC_PKCd_PRKCQ_ST	Q9Y4G8	RAPGEF2	Q04759	PRKCQ	S501	A506S	506	Missense	distal	5	no	1.840	1.838	EPSD	ICGC	1.204	Down-regulation
AGC_PKC_PKCd_PRKCQ_ST	Q9Y4G8	RAPGEF2	Q04759	PRKCQ	S912	V907L	907	Missense	distal	-5	no	1.529	1.549	EPSD	ICGC;COSMIC	1.204	Up-regulation
AGC_PKC_PKCd_PRKCQ_ST	Q9Y4G8	RAPGEF2	Q04759	PRKCQ	S912	A918T	918	Missense	distal	6	no	1.529	1.510	EPSD	ICGC;COSMIC	1.204	Down-regulation
AGC_PKC_PKCd_PRKCQ_ST	Q9Y4G8	RAPGEF2	Q04759	PRKCQ	S912	V907I	907	Missense	distal	-5	no	1.529	1.558	EPSD	ICGC;COSMIC	1.204	Up-regulation
AGC_PKC_PKCd_PRKCQ_ST	Q9Y4G8	RAPGEF2	Q04759	PRKCQ	S912	S912L	912	Missense	central	0	yes	1.529	0.000	EPSD	ICGC	1.204	Loss
AGC_PKC_PKCd_PRKCQ_ST	Q9Y4G8	RAPGEF2	Q04759	PRKCQ	S959	R957H	957	Missense	proximal	-2	no	1.710	1.107	EPSD	ICGC;COSMIC	1.204	Loss
AGC_PKC_PKCd_PRKCQ_ST	Q9Y4G8	RAPGEF2	Q04759	PRKCQ	S959	S959I	959	Missense	central	0	yes	1.710	0.000	EPSD	ICGC	1.204	Loss
AGC_PKC_PKCd_PRKCQ_ST	Q9Y4G8	RAPGEF2	Q04759	PRKCQ	S960	R957H	957	Missense	distal	-3	no	2.930	1.817	PhosphoSitePlus	ICGC;COSMIC	1.204	Down-regulation
AGC_PKC_PKCd_PRKCQ_ST	Q9Y4G8	RAPGEF2	Q04759	PRKCQ	S960	S959I	959	Missense	proximal	-1	no	2.930	2.926	PhosphoSitePlus	ICGC	1.204	Down-regulation
AGC_PKC_PKCd_PRKCQ_ST	Q9Y4G8	RAPGEF2	Q04759	PRKCQ	S1089	L1090F	1090	Missense	proximal	1	no	1.308	1.310	EPSD	ICGC	1.204	Up-regulation
AGC_PKC_PKCd_PRKCQ_ST	Q9Y4G8	RAPGEF2	Q04759	PRKCQ	S1153	V1155F	1155	Missense	proximal	2	no	1.545	1.615	EPSD	ICGC	1.204	Up-regulation
AGC_PKC_PKCd_PRKCQ_ST	Q9Y4G8	RAPGEF2	Q04759	PRKCQ	S1248	A1242S	1242	Missense	distal	-6	no	1.374	1.344	EPSD	ICGC;COSMIC	1.204	Down-regulation
AGC_PKC_PKCd_PRKCQ_ST	Q9Y4G8	RAPGEF2	Q04759	PRKCQ	S1316	R1323L	1323	Missense	distal	7	no	1.145	1.255	EPSD	ICGC	1.204	Gain
AGC_PKC_PKCd_PRKCQ_ST	Q9Y4G8	RAPGEF2	Q04759	PRKCQ	S1325	T1330K	1330	Missense	distal	5	no	1.277	1.296	EPSD	ICGC;COSMIC	1.204	Up-regulation
AGC_PKC_PKCd_PRKCQ_ST	Q9Y4G8	RAPGEF2	Q04759	PRKCQ	S1325	S1325I	1325	Missense	central	0	yes	1.277	0.000	EPSD	ICGC	1.204	Loss
AGC_PKC_PKCd_PRKCQ_ST	Q9Y4G8	RAPGEF2	Q04759	PRKCQ	S1325	R1323L	1323	Missense	proximal	-2	no	1.277	0.527	EPSD	ICGC	1.204	Loss
AGC_PKC_PKCd_PRKCQ_ST	Q13191	CBLB	Q04759	PRKCQ	S277	T278N	278	Missense	proximal	1	no	1.339	1.340	EPSD	ICGC;COSMIC	1.204	Up-regulation
AGC_PKC_PKCd_PRKCQ_ST	Q13191	CBLB	Q04759	PRKCQ	S277	A271E	271	Missense	distal	-6	no	1.339	1.392	EPSD	ICGC	1.204	Up-regulation
AGC_PKC_PKCd_PRKCQ_ST	Q13191	CBLB	Q04759	PRKCQ	S282	T278N	278	Missense	distal	-4	no	1.782	1.796	PhosphoSitePlus	ICGC;COSMIC	1.204	Up-regulation
AGC_PKC_PKCd_PRKCQ_ST	Q13191	CBLB	Q04759	PRKCQ	T471	N466D	466	Missense	distal	-5	no	1.691	1.647	EPSD	ICGC;COSMIC;GDSC	1.204	Down-regulation
AGC_PKC_PKCd_PRKCQ_ST	Q13191	CBLB	Q04759	PRKCQ	T471	V467I	467	Missense	distal	-4	no	1.691	1.697	EPSD	ICGC;COSMIC	1.204	Up-regulation
AGC_PKC_PKCd_PRKCQ_ST	Q13191	CBLB	Q04759	PRKCQ	S476	T479K	479	Missense	distal	3	no	1.610	1.625	EPSD	ICGC	1.204	Up-regulation
AGC_PKC_PKCd_PRKCQ_ST	Q13191	CBLB	Q04759	PRKCQ	S529	T527K	527	Missense	proximal	-2	no	1.060	1.502	EPSD	ICGC	1.204	Gain
AGC_PKC_PKCd_PRKCQ_ST	Q13191	CBLB	Q04759	PRKCQ	S533	T527K	527	Missense	distal	-6	no	1.241	1.095	EPSD	ICGC	1.204	Loss
AGC_PKC_PKCd_PRKCQ_ST	Q13191	CBLB	Q04759	PRKCQ	S533	P534L	534	Missense	proximal	1	no	1.241	1.237	EPSD	ICGC;COSMIC	1.204	Down-regulation
AGC_PKC_PKCd_PRKCQ_ST	Q13191	CBLB	Q04759	PRKCQ	S634	G633A	633	Missense	proximal	-1	no	1.742	1.744	EPSD	ICGC;COSMIC;GDSC;CCLE	1.204	Up-regulation
AGC_PKC_PKCd_PRKCQ_ST	Q13191	CBLB	Q04759	PRKCQ	S634	P636S	636	Missense	proximal	2	no	1.742	1.683	EPSD	ICGC;COSMIC	1.204	Down-regulation
AGC_PKC_PKCd_PRKCQ_ST	Q13191	CBLB	Q04759	PRKCQ	S634	P636Q	636	Missense	proximal	2	no	1.742	1.702	EPSD	ICGC;COSMIC	1.204	Down-regulation
AGC_PKC_PKCd_PRKCQ_ST	Q13191	CBLB	Q04759	PRKCQ	S656	S656A	656	Missense	central	0	yes	1.350	0.000	EPSD	ICGC;COSMIC	1.204	Loss
AGC_PKC_PKCd_PRKCQ_ST	Q13191	CBLB	Q04759	PRKCQ	S656	V654I	654	Missense	proximal	-2	no	1.350	1.408	EPSD	ICGC;COSMIC	1.204	Up-regulation
AGC_PKC_PKCd_PRKCQ_ST	Q13191	CBLB	Q04759	PRKCQ	S656	G658C	658	Missense	proximal	2	no	1.350	1.365	EPSD	ICGC;COSMIC	1.204	Up-regulation
AGC_PKC_PKCd_PRKCQ_ST	Q13191	CBLB	Q04759	PRKCQ	S672	P669L	669	Missense	distal	-3	no	1.394	1.031	EPSD	ICGC	1.204	Loss
AGC_PKC_PKCd_PRKCQ_ST	Q13191	CBLB	Q04759	PRKCQ	S672	P675S	675	Missense	distal	3	no	1.394	1.398	EPSD	ICGC;COSMIC	1.204	Up-regulation
AGC_PKC_PKCd_PRKCQ_ST	Q13191	CBLB	Q04759	PRKCQ	S793	L795F	795	Missense	proximal	2	no	1.494	1.548	EPSD	ICGC	1.204	Up-regulation
AGC_PKC_PKCd_PRKCQ_ST	Q13191	CBLB	Q04759	PRKCQ	S793	P789S	789	Missense	distal	-4	no	1.494	1.502	EPSD	ICGC	1.204	Up-regulation
AGC_PKC_PKCd_PRKCQ_ST	Q13191	CBLB	Q04759	PRKCQ	S800	L795F	795	Missense	distal	-5	no	1.372	1.426	EPSD	ICGC	1.204	Up-regulation
AGC_PKC_PKCd_PRKCQ_ST	Q5JVS0	HABP4	Q04759	PRKCQ	T375	R376P	376	Missense	proximal	1	no	1.246	1.231	PhosphoSitePlus;EPSD	ICGC;COSMIC	1.204	Down-regulation
AGC_PKC_PKCd_PRKCQ_ST	Q9UEW8	STK39	Q04759	PRKCQ	S323	A328E	328	Missense	distal	5	no	1.819	1.811	PhosphoSitePlus;EPSD	ICGC;COSMIC	1.204	Down-regulation
AGC_PKC_PKCd_PRKCQ_ST	Q9UEW8	STK39	Q04759	PRKCQ	S323	A328T	328	Missense	distal	5	no	1.819	1.812	PhosphoSitePlus;EPSD	ICGC;COSMIC	1.204	Down-regulation
AGC_PKC_PKCd_PRKCQ_ST	Q9UEW8	STK39	Q04759	PRKCQ	S430	Q427K	427	Missense	distal	-3	no	0.694	1.504	EPSD	ICGC	1.204	Gain
AGC_PKC_PKCd_PRKCQ_ST	Q9UEW8	STK39	Q04759	PRKCQ	S448	V455A	455	Missense	distal	7	no	1.421	1.381	EPSD	ICGC;COSMIC	1.204	Down-regulation
AGC_PKC_PKCd_PRKCQ_ST	Q9UEW8	STK39	Q04759	PRKCQ	S448	N453T	453	Missense	distal	5	no	1.421	1.417	EPSD	ICGC;COSMIC	1.204	Down-regulation
AGC_PKC_PKCd_PRKCQ_ST	Q9UEW8	STK39	Q04759	PRKCQ	S448	V455I	455	Missense	distal	7	no	1.421	1.409	EPSD	ICGC;COSMIC	1.204	Down-regulation
AGC_PKC_PKCd_PRKCQ_ST	Q9UEW8	STK39	Q04759	PRKCQ	S448	Y444C	444	Missense	distal	-4	no	1.421	1.418	EPSD	ICGC;COSMIC	1.204	Down-regulation
AGC_PKC_PKCd_PRKCQ_ST	P32942	ICAM3	Q04759	PRKCQ	S518	S525T	525	Missense	distal	7	no	2.100	2.122	PhosphoSitePlus	ICGC;COSMIC	1.204	Up-regulation
AGC_PKC_PKCd_PRKCQ_ST	P32942	ICAM3	Q04759	PRKCQ	S518	H513N	513	Missense	distal	-5	no	2.100	2.083	PhosphoSitePlus	ICGC	1.204	Down-regulation
AGC_PKC_PKCd_PRKCQ_ST	P32942	ICAM3	Q04759	PRKCQ	S518	R511M	511	Missense	distal	-7	no	2.100	2.120	PhosphoSitePlus	ICGC;COSMIC	1.204	Up-regulation
AGC_PKC_PKCd_PRKCQ_ST	P32942	ICAM3	Q04759	PRKCQ	S525	T526N	526	Missense	proximal	1	no	1.574	1.575	EPSD	ICGC	1.204	Up-regulation
AGC_PKC_PKCd_PRKCQ_ST	P32942	ICAM3	Q04759	PRKCQ	S525	S532Y	532	Missense	distal	7	no	1.574	1.584	EPSD	ICGC	1.204	Up-regulation
AGC_PKC_PKCd_PRKCQ_ST	O14974	PPP1R12A	Q04759	PRKCQ	S336	D343H	343	Missense	distal	7	no	1.562	1.542	EPSD	ICGC	1.204	Down-regulation
AGC_PKC_PKCd_PRKCQ_ST	O14974	PPP1R12A	Q04759	PRKCQ	S353	G348R	348	Missense	distal	-5	no	1.469	1.738	EPSD	ICGC;COSMIC	1.204	Up-regulation
AGC_PKC_PKCd_PRKCQ_ST	O14974	PPP1R12A	Q04759	PRKCQ	S365	E362K	362	Missense	distal	-3	no	0.216	1.233	EPSD	ICGC;COSMIC	1.204	Gain
AGC_PKC_PKCd_PRKCQ_ST	O14974	PPP1R12A	Q04759	PRKCQ	S432	P433S	433	Missense	proximal	1	no	1.559	1.558	EPSD	ICGC	1.204	Down-regulation
AGC_PKC_PKCd_PRKCQ_ST	O14974	PPP1R12A	Q04759	PRKCQ	S432	W436L	436	Missense	distal	4	no	1.559	1.552	EPSD	ICGC;COSMIC	1.204	Down-regulation
AGC_PKC_PKCd_PRKCQ_ST	O14974	PPP1R12A	Q04759	PRKCQ	S472	R469H	469	Missense	distal	-3	no	1.692	0.579	EPSD	ICGC;COSMIC	1.204	Loss
AGC_PKC_PKCd_PRKCQ_ST	O14974	PPP1R12A	Q04759	PRKCQ	S472	G466C	466	Missense	distal	-6	no	1.692	1.685	EPSD	ICGC;COSMIC	1.204	Down-regulation
AGC_PKC_PKCd_PRKCQ_ST	O14974	PPP1R12A	Q04759	PRKCQ	S472	S478Y	478	Missense	distal	6	no	1.692	1.678	EPSD	ICGC;COSMIC	1.204	Down-regulation
AGC_PKC_PKCd_PRKCQ_ST	O14974	PPP1R12A	Q04759	PRKCQ	S477	S478Y	478	Missense	proximal	1	no	1.608	1.606	EPSD	ICGC;COSMIC	1.204	Down-regulation
AGC_PKC_PKCd_PRKCQ_ST	O14974	PPP1R12A	Q04759	PRKCQ	S478	S478Y	478	Missense	central	0	yes	1.328	0.000	EPSD	ICGC;COSMIC	1.204	Loss
AGC_PKC_PKCd_PRKCQ_ST	O14974	PPP1R12A	Q04759	PRKCQ	S507	D510Y	510	Missense	distal	3	no	2.184	2.187	EPSD	ICGC;COSMIC	1.204	Up-regulation
AGC_PKC_PKCd_PRKCQ_ST	O14974	PPP1R12A	Q04759	PRKCQ	S507	D510H	510	Missense	distal	3	no	2.184	2.189	EPSD	ICGC;COSMIC	1.204	Up-regulation
AGC_PKC_PKCd_PRKCQ_ST	O14974	PPP1R12A	Q04759	PRKCQ	S541	N540Y	540	Missense	proximal	-1	no	2.101	2.100	EPSD	ICGC;COSMIC	1.204	Down-regulation
AGC_PKC_PKCd_PRKCQ_ST	O14974	PPP1R12A	Q04759	PRKCQ	S541	S542L	542	Missense	proximal	1	no	2.101	2.097	EPSD	ICGC;COSMIC	1.204	Down-regulation
AGC_PKC_PKCd_PRKCQ_ST	O14974	PPP1R12A	Q04759	PRKCQ	S541	L537F	537	Missense	distal	-4	no	2.101	2.110	EPSD	ICGC	1.204	Up-regulation
AGC_PKC_PKCd_PRKCQ_ST	O14974	PPP1R12A	Q04759	PRKCQ	S542	N540Y	540	Missense	proximal	-2	no	1.712	1.722	EPSD	ICGC;COSMIC	1.204	Up-regulation
AGC_PKC_PKCd_PRKCQ_ST	O14974	PPP1R12A	Q04759	PRKCQ	S542	S542L	542	Missense	central	0	yes	1.712	0.000	EPSD	ICGC;COSMIC	1.204	Loss
AGC_PKC_PKCd_PRKCQ_ST	O14974	PPP1R12A	Q04759	PRKCQ	S542	L537F	537	Missense	distal	-5	no	1.712	1.766	EPSD	ICGC	1.204	Up-regulation
AGC_PKC_PKCd_PRKCQ_ST	O14974	PPP1R12A	Q04759	PRKCQ	S668	R666H	666	Missense	proximal	-2	no	2.668	2.065	EPSD	ICGC;COSMIC	1.204	Down-regulation
AGC_PKC_PKCd_PRKCQ_ST	O14974	PPP1R12A	Q04759	PRKCQ	S668	R666C	666	Missense	proximal	-2	no	2.668	1.964	EPSD	ICGC	1.204	Down-regulation
AGC_PKC_PKCd_PRKCQ_ST	O14974	PPP1R12A	Q04759	PRKCQ	S686	Q681K	681	Missense	distal	-5	no	1.839	1.999	EPSD	ICGC;COSMIC	1.204	Up-regulation
AGC_PKC_PKCd_PRKCQ_ST	O14974	PPP1R12A	Q04759	PRKCQ	S686	A684G	684	Missense	proximal	-2	no	1.839	1.790	EPSD	ICGC	1.204	Down-regulation
AGC_PKC_PKCd_PRKCQ_ST	O14974	PPP1R12A	Q04759	PRKCQ	S716	T710A	710	Missense	distal	-6	no	2.440	2.392	EPSD	ICGC;COSMIC	1.204	Down-regulation
AGC_PKC_PKCd_PRKCQ_ST	O14974	PPP1R12A	Q04759	PRKCQ	S852	R850K	850	Missense	proximal	-2	no	2.201	1.957	EPSD	ICGC	1.204	Down-regulation
AGC_PKC_PKCd_PRKCQ_ST	O14974	PPP1R12A	Q04759	PRKCQ	S852	R845Q	845	Missense	distal	-7	no	2.201	2.222	EPSD	ICGC	1.204	Up-regulation
AGC_PKC_PKCd_PRKCQ_ST	O14974	PPP1R12A	Q04759	PRKCQ	T853	R850K	850	Missense	distal	-3	no	1.351	0.933	PhosphoSitePlus	ICGC	1.204	Loss
AGC_PKC_PKCd_PRKCQ_ST	O14974	PPP1R12A	Q04759	PRKCQ	S903	S896L	896	Missense	distal	-7	no	1.716	1.720	EPSD	ICGC	1.204	Up-regulation
AGC_PKC_PKCd_PRKCQ_ST	O14974	PPP1R12A	Q04759	PRKCQ	S903	R907H	907	Missense	distal	4	no	1.716	1.566	EPSD	ICGC;COSMIC	1.204	Down-regulation
AGC_PKC_PKCd_PRKCQ_ST	O14974	PPP1R12A	Q04759	PRKCQ	S903	G909R	909	Missense	distal	6	no	1.716	1.768	EPSD	ICGC;COSMIC	1.204	Up-regulation
AGC_PKC_PKCd_PRKCQ_ST	O14974	PPP1R12A	Q04759	PRKCQ	S910	R917G	917	Missense	distal	7	no	1.794	1.905	EPSD	ICGC;COSMIC	1.204	Up-regulation
AGC_PKC_PKCd_PRKCQ_ST	O14974	PPP1R12A	Q04759	PRKCQ	S910	R907H	907	Missense	distal	-3	no	1.794	0.681	EPSD	ICGC;COSMIC	1.204	Loss
AGC_PKC_PKCd_PRKCQ_ST	O14974	PPP1R12A	Q04759	PRKCQ	S910	G909R	909	Missense	proximal	-1	no	1.794	1.806	EPSD	ICGC;COSMIC	1.204	Up-regulation
AGC_PKC_PKCd_PRKCQ_ST	O14974	PPP1R12A	Q04759	PRKCQ	S912	G909R	909	Missense	distal	-3	no	0.894	2.212	EPSD	ICGC;COSMIC	1.204	Gain
AGC_PKC_PKCd_PRKCQ_ST	O14974	PPP1R12A	Q04759	PRKCQ	S921	R917G	917	Missense	distal	-4	no	1.657	1.599	EPSD	ICGC;COSMIC	1.204	Down-regulation
AGC_PKC_PKCd_PRKCQ_ST	O14974	PPP1R12A	Q04759	PRKCQ	S922	R917G	917	Missense	distal	-5	no	1.269	1.000	EPSD	ICGC;COSMIC	1.204	Loss
AGC_PKC_PKCd_PRKCQ_ST	O14974	PPP1R12A	Q04759	PRKCQ	S922	L924I	924	Missense	proximal	2	no	1.269	1.281	EPSD	ICGC	1.204	Up-regulation
AGC_PKC_PKCd_PRKCQ_ST	O14974	PPP1R12A	Q04759	PRKCQ	S929	L924I	924	Missense	distal	-5	no	1.417	1.426	EPSD	ICGC	1.204	Up-regulation
AGC_PKC_PKCd_PRKCQ_ST	Q15052	ARHGEF6	Q04759	PRKCQ	S101	N107K	107	Missense	distal	6	no	1.420	1.450	EPSD	ICGC	1.204	Up-regulation
AGC_PKC_PKCd_PRKCQ_ST	Q15052	ARHGEF6	Q04759	PRKCQ	S144	T142K	142	Missense	proximal	-2	no	0.778	1.220	EPSD	ICGC	1.204	Gain
AGC_PKC_PKCd_PRKCQ_ST	Q15052	ARHGEF6	Q04759	PRKCQ	S150	T152N	152	Missense	proximal	2	no	1.234	1.253	EPSD	ICGC	1.204	Up-regulation
AGC_PKC_PKCd_PRKCQ_ST	Q15052	ARHGEF6	Q04759	PRKCQ	S150	M155L	155	Missense	distal	5	no	1.234	1.227	EPSD	ICGC;COSMIC	1.204	Down-regulation
AGC_PKC_PKCd_PRKCQ_ST	Q8IV61	RASGRP3	Q04759	PRKCQ	T133	V138L	138	Missense	distal	5	no	2.341	2.344	PhosphoSitePlus	ICGC;COSMIC	1.204	Up-regulation
AGC_PKC_PKCd_PRKCQ_ST	Q8IV61	RASGRP3	Q04759	PRKCQ	T133	D127Y	127	Missense	distal	-6	no	2.341	2.310	PhosphoSitePlus	ICGC	1.204	Down-regulation
AGC_PKC_PKCd_PRKCQ_ST	Q8IV61	RASGRP3	Q04759	PRKCQ	T133	V138I	138	Missense	distal	5	no	2.341	2.345	PhosphoSitePlus	ICGC	1.204	Up-regulation
AGC_PKC_PKCd_PRKCQ_ST	Q8IV61	RASGRP3	Q04759	PRKCQ	S385	R383I	383	Missense	proximal	-2	no	1.489	0.756	EPSD	ICGC	1.204	Loss
AGC_PKC_PKCd_PRKCQ_ST	Q8IV61	RASGRP3	Q04759	PRKCQ	S385	T390S	390	Missense	distal	5	no	1.489	1.494	EPSD	ICGC;COSMIC	1.204	Up-regulation
AGC_PKC_PKCd_PRKCQ_ST	Q8IV61	RASGRP3	Q04759	PRKCQ	S552	R545M	545	Missense	distal	-7	no	1.608	1.628	EPSD	ICGC;COSMIC	1.204	Up-regulation
AGC_PKC_PKCd_PRKCQ_ST	Q8IV61	RASGRP3	Q04759	PRKCQ	S552	A550V	550	Missense	proximal	-2	no	1.608	1.491	EPSD	ICGC;COSMIC;GDSC;CCLE	1.204	Down-regulation
AGC_PKC_PKCd_PRKCQ_ST	Q8IV61	RASGRP3	Q04759	PRKCQ	S552	R549Q	549	Missense	distal	-3	no	1.608	0.380	EPSD	ICGC;COSMIC	1.204	Loss
AGC_PKC_PKCd_PRKCQ_ST	Q8IV61	RASGRP3	Q04759	PRKCQ	S638	M636I	636	Missense	proximal	-2	no	1.681	1.570	EPSD	ICGC;COSMIC;GDSC;CCLE	1.204	Down-regulation
AGC_PKA_PRKACB_ST	Q01130	SRSF2	P22694	PRKACB	S98	P95R	95	Missense	distal	-3	no	1.723	3.222	EPSD	ICGC;COSMIC	2.323	Gain
AGC_PKA_PRKACB_ST	Q01130	SRSF2	P22694	PRKACB	S121	R117L	117	Missense	distal	-4	no	3.788	3.811	PhosphoSitePlus;EPSD	ICGC;COSMIC	2.323	Up-regulation
AGC_PKA_PRKACB_ST	Q01130	SRSF2	P22694	PRKACB	S121	R120L	120	Missense	proximal	-1	no	3.788	3.828	PhosphoSitePlus;EPSD	ICGC;COSMIC	2.323	Up-regulation
AGC_PKA_PRKACB_ST	Q01130	SRSF2	P22694	PRKACB	S128	R135S	135	Missense	distal	7	no	2.373	2.397	EPSD;PhosphoSitePlus	ICGC	2.323	Up-regulation
AGC_PKA_PRKACB_ST	Q01130	SRSF2	P22694	PRKACB	S130	R135S	135	Missense	distal	5	no	2.496	2.497	EPSD;PhosphoSitePlus	ICGC	2.323	Up-regulation
AGC_PKA_PRKACB_ST	Q01130	SRSF2	P22694	PRKACB	S134	R135S	135	Missense	proximal	1	no	2.934	3.026	EPSD	ICGC	2.323	Up-regulation
AGC_PKA_PRKACB_ST	Q01130	SRSF2	P22694	PRKACB	S136	R135S	135	Missense	proximal	-1	no	3.388	3.428	EPSD	ICGC	2.323	Up-regulation
AGC_PKA_PRKACB_ST	Q01130	SRSF2	P22694	PRKACB	T153	R156K	156	Missense	distal	3	no	2.409	2.293	EPSD	ICGC;COSMIC	2.323	Loss
AGC_PKA_PRKACB_ST	Q01130	SRSF2	P22694	PRKACB	S191	P193S	193	Missense	proximal	2	no	3.821	3.769	EPSD	ICGC;COSMIC	2.323	Down-regulation
AGC_PKA_PRKACB_ST	Q01130	SRSF2	P22694	PRKACB	S200	P193S	193	Missense	distal	-7	no	3.925	4.018	EPSD	ICGC;COSMIC	2.323	Up-regulation
CK1_CK1_CK1-G_CSNK1G1_ST	P25054	APC	Q9HCP0	CSNK1G1	S95	S92C	92	Missense	distal	-3	no	2.401	2.062	EPSD	ICGC;COSMIC	1.928	Down-regulation
CK1_CK1_CK1-G_CSNK1G1_ST	P25054	APC	Q9HCP0	CSNK1G1	S95	L93I	93	Missense	proximal	-2	no	2.401	2.392	EPSD	ICGC;COSMIC	1.928	Down-regulation
CK1_CK1_CK1-G_CSNK1G1_ST	P25054	APC	Q9HCP0	CSNK1G1	S95	R88L	88	Missense	distal	-7	no	2.401	2.411	EPSD	ICGC;COSMIC	1.928	Up-regulation
CK1_CK1_CK1-G_CSNK1G1_ST	P25054	APC	Q9HCP0	CSNK1G1	S98	S92C	92	Missense	distal	-6	no	2.046	1.263	EPSD	ICGC;COSMIC	1.928	Loss
CK1_CK1_CK1-G_CSNK1G1_ST	P25054	APC	Q9HCP0	CSNK1G1	S98	L93I	93	Missense	distal	-5	no	2.046	2.040	EPSD	ICGC;COSMIC	1.928	Down-regulation
CK1_CK1_CK1-G_CSNK1G1_ST	P25054	APC	Q9HCP0	CSNK1G1	S299	S294Y	294	Missense	distal	-5	no	1.952	2.053	EPSD	ICGC;COSMIC	1.928	Up-regulation
CK1_CK1_CK1-G_CSNK1G1_ST	P25054	APC	Q9HCP0	CSNK1G1	S299	R302P	302	Missense	distal	3	no	1.952	1.928	EPSD	ICGC	1.928	Down-regulation
CK1_CK1_CK1-G_CSNK1G1_ST	P25054	APC	Q9HCP0	CSNK1G1	S299	R302L	302	Missense	distal	3	no	1.952	1.949	EPSD	ICGC	1.928	Down-regulation
CK1_CK1_CK1-G_CSNK1G1_ST	P25054	APC	Q9HCP0	CSNK1G1	S299	S293I	293	Missense	distal	-6	no	1.952	1.062	EPSD	ICGC	1.928	Loss
CK1_CK1_CK1-G_CSNK1G1_ST	P25054	APC	Q9HCP0	CSNK1G1	S299	S306I	306	Missense	distal	7	no	1.952	1.959	EPSD	ICGC	1.928	Up-regulation
CK1_CK1_CK1-G_CSNK1G1_ST	P25054	APC	Q9HCP0	CSNK1G1	S559	V557A	557	Missense	proximal	-2	no	2.048	2.030	EPSD	ICGC;COSMIC	1.928	Down-regulation
CK1_CK1_CK1-G_CSNK1G1_ST	P25054	APC	Q9HCP0	CSNK1G1	S559	W553L	553	Missense	distal	-6	no	2.048	2.040	EPSD	ICGC;COSMIC	1.928	Down-regulation
CK1_CK1_CK1-G_CSNK1G1_ST	P25054	APC	Q9HCP0	CSNK1G1	S559	A555S	555	Missense	distal	-4	no	2.048	2.073	EPSD	ICGC	1.928	Up-regulation
CK1_CK1_CK1-G_CSNK1G1_ST	P25054	APC	Q9HCP0	CSNK1G1	S559	R554Q	554	Missense	distal	-5	no	2.048	2.055	EPSD	ICGC;COSMIC	1.928	Up-regulation
CK1_CK1_CK1-G_CSNK1G1_ST	P25054	APC	Q9HCP0	CSNK1G1	S751	P750S	750	Missense	proximal	-1	no	1.836	2.027	EPSD	ICGC;COSMIC	1.928	Gain
CK1_CK1_CK1-G_CSNK1G1_ST	P25054	APC	Q9HCP0	CSNK1G1	S780	R786C	786	Missense	distal	6	no	2.279	2.274	EPSD	ICGC;COSMIC	1.928	Down-regulation
CK1_CK1_CK1-G_CSNK1G1_ST	P25054	APC	Q9HCP0	CSNK1G1	T867	H864N	864	Missense	distal	-3	no	1.988	2.112	EPSD	ICGC;COSMIC	1.928	Up-regulation
CK1_CK1_CK1-G_CSNK1G1_ST	P25054	APC	Q9HCP0	CSNK1G1	S874	G877D	877	Missense	distal	3	no	2.555	2.609	EPSD	ICGC	1.928	Up-regulation
CK1_CK1_CK1-G_CSNK1G1_ST	P25054	APC	Q9HCP0	CSNK1G1	S874	S881F	881	Missense	distal	7	no	2.555	2.571	EPSD	ICGC	1.928	Up-regulation
CK1_CK1_CK1-G_CSNK1G1_ST	P25054	APC	Q9HCP0	CSNK1G1	S874	R876Q	876	Missense	proximal	2	no	2.555	2.533	EPSD	ICGC;COSMIC	1.928	Down-regulation
CK1_CK1_CK1-G_CSNK1G1_ST	P25054	APC	Q9HCP0	CSNK1G1	S963	S969I	969	Missense	distal	6	no	3.170	3.263	EPSD	ICGC;COSMIC	1.928	Up-regulation
CK1_CK1_CK1-G_CSNK1G1_ST	P25054	APC	Q9HCP0	CSNK1G1	S963	S959P	959	Missense	distal	-4	no	3.170	3.109	EPSD	ICGC;COSMIC	1.928	Down-regulation
CK1_CK1_CK1-G_CSNK1G1_ST	P25054	APC	Q9HCP0	CSNK1G1	S1371	A1366V	1366	Missense	distal	-5	no	1.970	1.961	EPSD	ICGC;COSMIC	1.928	Down-regulation
CK1_CK1_CK1-G_CSNK1G1_ST	P25054	APC	Q9HCP0	CSNK1G1	S1507	E1513D	1513	Missense	distal	6	no	5.668	5.688	PhosphoSitePlus;EPSD	ICGC	1.928	Up-regulation
CK1_CK1_CK1-G_CSNK1G1_ST	P25054	APC	Q9HCP0	CSNK1G1	S1510	E1513D	1513	Missense	distal	3	no	5.287	5.407	EPSD;PhosphoSitePlus	ICGC	1.928	Up-regulation
CK1_CK1_CK1-G_CSNK1G1_ST	P25054	APC	Q9HCP0	CSNK1G1	S1539	G1534W	1534	Missense	distal	-5	no	2.392	2.456	EPSD	ICGC;COSMIC	1.928	Up-regulation
CK1_CK1_CK1-G_CSNK1G1_ST	P25054	APC	Q9HCP0	CSNK1G1	S1539	D1532G	1532	Missense	distal	-7	no	2.392	2.306	EPSD	ICGC;COSMIC	1.928	Down-regulation
CK1_CK1_CK1-G_CSNK1G1_ST	P25054	APC	Q9HCP0	CSNK1G1	S1539	E1536D	1536	Missense	distal	-3	no	2.392	2.777	EPSD	ICGC;COSMIC	1.928	Up-regulation
CK1_CK1_CK1-G_CSNK1G1_ST	P25054	APC	Q9HCP0	CSNK1G1	S1652	T1647A	1647	Missense	distal	-5	no	2.224	2.286	EPSD	ICGC	1.928	Up-regulation
CK1_CK1_CK1-G_CSNK1G1_ST	P25054	APC	Q9HCP0	CSNK1G1	S1658	P1665S	1665	Missense	distal	7	no	2.003	1.997	EPSD	ICGC;COSMIC	1.928	Down-regulation
CK1_CK1_CK1-G_CSNK1G1_ST	P25054	APC	Q9HCP0	CSNK1G1	T1661	P1665S	1665	Missense	distal	4	no	2.545	2.598	EPSD	ICGC;COSMIC	1.928	Up-regulation
CK1_CK1_CK1-G_CSNK1G1_ST	P25054	APC	Q9HCP0	CSNK1G1	S1861	R1858L	1858	Missense	distal	-3	no	1.959	1.970	EPSD	ICGC;COSMIC	1.928	Up-regulation
CK1_CK1_CK1-G_CSNK1G1_ST	P25054	APC	Q9HCP0	CSNK1G1	S1863	R1858L	1858	Missense	distal	-5	no	2.538	2.537	EPSD	ICGC;COSMIC	1.928	Down-regulation
CK1_CK1_CK1-G_CSNK1G1_ST	P25054	APC	Q9HCP0	CSNK1G1	S2034	Q2040P	2040	Missense	distal	6	no	2.197	1.819	EPSD	ICGC;COSMIC	1.928	Loss
CK1_CK1_CK1-G_CSNK1G1_ST	P25054	APC	Q9HCP0	CSNK1G1	S2034	S2028I	2028	Missense	distal	-6	no	2.197	1.308	EPSD	ICGC	1.928	Loss
CK1_CK1_CK1-G_CSNK1G1_ST	P25054	APC	Q9HCP0	CSNK1G1	S2034	S2031I	2031	Missense	distal	-3	no	2.197	1.713	EPSD	ICGC;COSMIC	1.928	Loss
CK1_CK1_CK1-G_CSNK1G1_ST	P25054	APC	Q9HCP0	CSNK1G1	S2146	G2145R	2145	Missense	proximal	-1	no	2.097	1.972	EPSD	ICGC;COSMIC	1.928	Down-regulation
CK1_CK1_CK1-G_CSNK1G1_ST	P25054	APC	Q9HCP0	CSNK1G1	S2146	L2144M	2144	Missense	proximal	-2	no	2.097	2.099	EPSD	ICGC;COSMIC	1.928	Up-regulation
CK1_CK1_CK1-G_CSNK1G1_ST	P25054	APC	Q9HCP0	CSNK1G1	T2308	R2305T	2305	Missense	distal	-3	no	1.705	2.012	EPSD	ICGC;COSMIC	1.928	Gain
CK1_CK1_CK1-G_CSNK1G1_ST	P25054	APC	Q9HCP0	CSNK1G1	S2349	S2350F	2350	Missense	proximal	1	no	1.975	1.875	EPSD	ICGC;COSMIC	1.928	Loss
CK1_CK1_CK1-G_CSNK1G1_ST	P25054	APC	Q9HCP0	CSNK1G1	S2359	M2364I	2364	Missense	distal	5	no	2.784	2.785	EPSD	ICGC;COSMIC	1.928	Up-regulation
CK1_CK1_CK1-G_CSNK1G1_ST	P25054	APC	Q9HCP0	CSNK1G1	S2359	K2357T	2357	Missense	proximal	-2	no	2.784	2.817	EPSD	ICGC;COSMIC	1.928	Up-regulation
CK1_CK1_CK1-G_CSNK1G1_ST	P25054	APC	Q9HCP0	CSNK1G1	S2427	S2432L	2432	Missense	distal	5	no	2.689	2.685	EPSD	ICGC;COSMIC	1.928	Down-regulation
CK1_CK1_CK1-G_CSNK1G1_ST	P25054	APC	Q9HCP0	CSNK1G1	S2427	R2431K	2431	Missense	distal	4	no	2.689	2.620	EPSD	ICGC;COSMIC	1.928	Down-regulation
CK1_CK1_CK1-G_CSNK1G1_ST	P25054	APC	Q9HCP0	CSNK1G1	S2466	R2470I	2470	Missense	distal	4	no	1.876	1.934	EPSD	ICGC	1.928	Gain
CK1_CK1_CK1-G_CSNK1G1_ST	P25054	APC	Q9HCP0	CSNK1G1	S2575	S2581R	2581	Missense	distal	6	no	2.091	1.964	EPSD	ICGC;COSMIC	1.928	Down-regulation
CK1_CK1_CK1-G_CSNK1G1_ST	P25054	APC	Q9HCP0	CSNK1G1	S2627	V2630I	2630	Missense	distal	3	no	2.082	2.044	EPSD	ICGC;COSMIC	1.928	Down-regulation
CK1_CK1_CK1-G_CSNK1G1_ST	P25054	APC	Q9HCP0	CSNK1G1	S2627	S2621C	2621	Missense	distal	-6	no	2.082	1.300	EPSD	ICGC;COSMIC;GDSC	1.928	Loss
CK1_CK1_CK1-G_CSNK1G1_ST	P25054	APC	Q9HCP0	CSNK1G1	S2627	S2625C	2625	Missense	proximal	-2	no	2.082	2.065	EPSD	ICGC	1.928	Down-regulation
CK1_CK1_CK1-G_CSNK1G1_ST	P25054	APC	Q9HCP0	CSNK1G1	S2627	G2633C	2633	Missense	distal	6	no	2.082	2.004	EPSD	ICGC;COSMIC	1.928	Down-regulation
CK1_CK1_CK1-G_CSNK1G1_ST	O75581	LRP6	Q9HCP0	CSNK1G1	S172	R173L	173	Missense	proximal	1	no	1.858	2.085	EPSD	ICGC;COSMIC	1.928	Gain
CK1_CK1_CK1-G_CSNK1G1_ST	O75581	LRP6	Q9HCP0	CSNK1G1	S646	A640V	640	Missense	distal	-6	no	2.084	2.098	EPSD	ICGC	1.928	Up-regulation
CK1_CK1_CK1-G_CSNK1G1_ST	O75581	LRP6	Q9HCP0	CSNK1G1	S646	A640E	640	Missense	distal	-6	no	2.084	2.220	EPSD	ICGC	1.928	Up-regulation
CK1_CK1_CK1-G_CSNK1G1_ST	Q04206	RELA	Q9HCP0	CSNK1G1	S311	P317H	317	Missense	distal	6	no	1.998	2.298	EPSD	ICGC;COSMIC	1.928	Up-regulation
CK1_CK1_CK1-G_CSNK1G1_ST	Q04206	RELA	Q9HCP0	CSNK1G1	S311	S311G	311	Missense	central	0	yes	1.998	0.000	EPSD	ICGC;COSMIC	1.928	Loss
CK1_CK1_CK1-G_CSNK1G1_ST	Q04206	RELA	Q9HCP0	CSNK1G1	S468	D470E	470	Missense	proximal	2	no	2.623	2.583	EPSD	ICGC	1.928	Down-regulation
CK1_CK1_CK1-G_CSNK1G1_ST	Q04206	RELA	Q9HCP0	CSNK1G1	S472	D470E	470	Missense	proximal	-2	no	2.443	2.405	EPSD	ICGC	1.928	Down-regulation
CK1_CK1_CK1-G_CSNK1G1_ST	Q04206	RELA	Q9HCP0	CSNK1G1	S472	N479K	479	Missense	distal	7	no	2.443	2.449	EPSD	ICGC	1.928	Up-regulation
CK1_CK1_CK1-G_CSNK1G1_ST	Q04206	RELA	Q9HCP0	CSNK1G1	S536	A538V	538	Missense	proximal	2	no	3.108	3.046	PhosphoSitePlus	ICGC;COSMIC	1.928	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	P12931	SRC	O14757	CHEK1	S12	K7N	7	Missense	distal	-5	no	8.908	8.014	EPSD	ICGC	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	P12931	SRC	O14757	CHEK1	S12	R14L	14	Missense	proximal	2	no	8.908	8.609	EPSD	ICGC;COSMIC	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	P12931	SRC	O14757	CHEK1	S12	Q13K	13	Missense	proximal	1	no	8.908	8.900	EPSD	ICGC;COSMIC	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	P12931	SRC	O14757	CHEK1	S17	R14L	14	Missense	distal	-3	no	9.633	-8.914	EPSD	ICGC;COSMIC	5.604	Loss
CAMK_CAMKL_CHK1_CHEK1_ST	P12931	SRC	O14757	CHEK1	S17	Q13K	13	Missense	distal	-4	no	9.633	9.574	EPSD	ICGC;COSMIC	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	P12931	SRC	O14757	CHEK1	S43	S43L	43	Missense	central	0	yes	5.985	0.000	EPSD	ICGC;COSMIC	5.604	Loss
CAMK_CAMKL_CHK1_CHEK1_ST	P12931	SRC	O14757	CHEK1	S51	A52T	52	Missense	proximal	1	no	11.266	11.255	PhosphoSitePlus;EPSD	ICGC;COSMIC	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	P12931	SRC	O14757	CHEK1	T246	P253L	253	Missense	distal	7	no	7.750	7.687	EPSD	ICGC;COSMIC	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	P12931	SRC	O14757	CHEK1	T246	P253Q	253	Missense	distal	7	no	7.750	7.942	EPSD	ICGC;COSMIC	5.604	Up-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q6PD62	CTR9	O14757	CHEK1	T766	V768F	768	Missense	proximal	2	no	8.467	8.429	EPSD	ICGC	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q6PD62	CTR9	O14757	CHEK1	T766	D771Y	771	Missense	distal	5	no	8.467	7.926	EPSD	ICGC	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q6PD62	CTR9	O14757	CHEK1	S941	E948D	948	Missense	distal	7	no	12.944	13.001	EPSD	ICGC;COSMIC	5.604	Up-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q6PD62	CTR9	O14757	CHEK1	S1054	A1053S	1053	Missense	proximal	-1	no	9.751	9.418	EPSD	ICGC	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q6PD62	CTR9	O14757	CHEK1	S1072	E1069K	1069	Missense	distal	-3	no	2.740	6.003	EPSD	ICGC;COSMIC	5.604	Gain
CAMK_CAMKL_CHK1_CHEK1_ST	Q6PD62	CTR9	O14757	CHEK1	S1081	S1085L	1085	Missense	distal	4	no	8.022	8.058	PhosphoSitePlus	ICGC;COSMIC	5.604	Up-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q6PD62	CTR9	O14757	CHEK1	S1097	P1090S	1090	Missense	distal	-7	no	9.646	10.316	EPSD	ICGC;COSMIC	5.604	Up-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q6PD62	CTR9	O14757	CHEK1	S1097	S1097Y	1097	Missense	central	0	yes	9.646	0.000	EPSD	ICGC;COSMIC	5.604	Loss
CAMK_CAMKL_CHK1_CHEK1_ST	Q6PD62	CTR9	O14757	CHEK1	S1125	R1122H	1122	Missense	distal	-3	no	6.650	0.840	EPSD	ICGC;COSMIC	5.604	Loss
CAMK_CAMKL_CHK1_CHEK1_ST	Q6PD62	CTR9	O14757	CHEK1	S1125	R1122L	1122	Missense	distal	-3	no	6.650	-11.897	EPSD	ICGC;COSMIC	5.604	Loss
CAMK_CAMKL_CHK1_CHEK1_ST	P11047	LAMC1	O14757	CHEK1	T154	R149L	149	Missense	distal	-5	no	5.186	8.163	EPSD	ICGC	5.604	Gain
CAMK_CAMKL_CHK1_CHEK1_ST	P11047	LAMC1	O14757	CHEK1	S159	A161S	161	Missense	proximal	2	no	7.612	7.156	EPSD	ICGC	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	P11047	LAMC1	O14757	CHEK1	S159	R165L	165	Missense	distal	6	no	7.612	7.934	EPSD	ICGC	5.604	Up-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	P11047	LAMC1	O14757	CHEK1	S159	R156H	156	Missense	distal	-3	no	7.612	1.803	EPSD	ICGC;COSMIC;GDSC;CCLE	5.604	Loss
CAMK_CAMKL_CHK1_CHEK1_ST	P11047	LAMC1	O14757	CHEK1	T258	F259L	259	Missense	proximal	1	no	13.605	13.601	PhosphoSitePlus	ICGC;COSMIC	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	P11047	LAMC1	O14757	CHEK1	T258	E262K	262	Missense	distal	4	no	13.605	13.599	PhosphoSitePlus	ICGC;COSMIC	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	P11047	LAMC1	O14757	CHEK1	S1552	D1553N	1553	Missense	proximal	1	no	6.723	6.615	EPSD	ICGC;COSMIC	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	P11047	LAMC1	O14757	CHEK1	S1552	V1551A	1551	Missense	proximal	-1	no	6.723	6.801	EPSD	ICGC;COSMIC	5.604	Up-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	P11047	LAMC1	O14757	CHEK1	S1559	D1553N	1553	Missense	distal	-6	no	14.923	15.136	EPSD	ICGC;COSMIC	5.604	Up-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	P22626	HNRNPA2B1	O14757	CHEK1	S85	H84Q	84	Missense	proximal	-1	no	7.328	7.218	EPSD	ICGC;COSMIC	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	P22626	HNRNPA2B1	O14757	CHEK1	S85	M79T	79	Missense	distal	-6	no	7.328	7.335	EPSD	ICGC;COSMIC	5.604	Up-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	P22626	HNRNPA2B1	O14757	CHEK1	S189	M193I	193	Missense	distal	4	no	8.250	8.191	EPSD	ICGC;COSMIC	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	P22626	HNRNPA2B1	O14757	CHEK1	S231	D232G	232	Missense	proximal	1	no	7.700	7.613	EPSD	ICGC;COSMIC	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	P84098	RPL19	O14757	CHEK1	T56	R60G	60	Missense	distal	4	no	5.624	5.640	PhosphoSitePlus;EPSD	ICGC;COSMIC	5.604	Up-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	P84098	RPL19	O14757	CHEK1	T56	R52H	52	Missense	distal	-4	no	5.624	5.426	PhosphoSitePlus;EPSD	ICGC	5.604	Loss
CAMK_CAMKL_CHK1_CHEK1_ST	P84098	RPL19	O14757	CHEK1	T56	V55L	55	Missense	proximal	-1	no	5.624	5.629	PhosphoSitePlus;EPSD	ICGC;CCLE	5.604	Up-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	P84098	RPL19	O14757	CHEK1	T67	R60G	60	Missense	distal	-7	no	10.349	10.387	EPSD	ICGC;COSMIC	5.604	Up-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	P84098	RPL19	O14757	CHEK1	T67	K72E	72	Missense	distal	5	no	10.349	10.414	EPSD	ICGC;COSMIC	5.604	Up-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	P84098	RPL19	O14757	CHEK1	T84	R81Q	81	Missense	distal	-3	no	9.913	2.706	EPSD	ICGC	5.604	Loss
CAMK_CAMKL_CHK1_CHEK1_ST	P84098	RPL19	O14757	CHEK1	T84	I78M	78	Missense	distal	-6	no	9.913	9.977	EPSD	ICGC;COSMIC	5.604	Up-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	P84098	RPL19	O14757	CHEK1	T84	G79C	79	Missense	distal	-5	no	9.913	9.400	EPSD	ICGC;COSMIC	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	P84098	RPL19	O14757	CHEK1	T84	R81L	81	Missense	distal	-3	no	9.913	-8.633	EPSD	ICGC;COSMIC	5.604	Loss
CAMK_CAMKL_CHK1_CHEK1_ST	P84098	RPL19	O14757	CHEK1	T84	R81W	81	Missense	distal	-3	no	9.913	-23.690	EPSD	ICGC;COSMIC	5.604	Loss
CAMK_CAMKL_CHK1_CHEK1_ST	P84098	RPL19	O14757	CHEK1	S189	E193D	193	Missense	distal	4	no	6.586	6.678	EPSD	ICGC;COSMIC	5.604	Up-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	P84098	RPL19	O14757	CHEK1	S189	E191D	191	Missense	proximal	2	no	6.586	6.503	EPSD	ICGC;COSMIC	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	P67809	YBX1	O14757	CHEK1	T80	K81E	81	Missense	proximal	1	no	12.148	12.222	PhosphoSitePlus	ICGC;COSMIC	5.604	Up-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	P67809	YBX1	O14757	CHEK1	T80	V84L	84	Missense	distal	4	no	12.148	12.073	PhosphoSitePlus	ICGC;COSMIC	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	P67809	YBX1	O14757	CHEK1	T80	D79Y	79	Missense	proximal	-1	no	12.148	12.347	PhosphoSitePlus	ICGC	5.604	Up-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	P67809	YBX1	O14757	CHEK1	S176	P178T	178	Missense	proximal	2	no	6.877	6.562	EPSD	ICGC;COSMIC	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q7Z2Z1	TICRR	O14757	CHEK1	S599	P600L	600	Missense	proximal	1	no	5.599	5.627	EPSD	ICGC;GDSC;CCLE	5.604	Gain
CAMK_CAMKL_CHK1_CHEK1_ST	Q7Z2Z1	TICRR	O14757	CHEK1	S836	S830R	830	Missense	distal	-6	no	7.648	7.568	EPSD	ICGC;COSMIC	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q7Z2Z1	TICRR	O14757	CHEK1	S851	E846K	846	Missense	distal	-5	no	7.281	9.843	EPSD	ICGC;COSMIC	5.604	Up-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q7Z2Z1	TICRR	O14757	CHEK1	S865	R862K	862	Missense	distal	-3	no	12.767	8.942	EPSD;PhosphoSitePlus	ICGC;COSMIC	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q7Z2Z1	TICRR	O14757	CHEK1	S865	N872S	872	Missense	distal	7	no	12.767	12.538	EPSD;PhosphoSitePlus	ICGC;COSMIC	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q7Z2Z1	TICRR	O14757	CHEK1	S891	K887E	887	Missense	distal	-4	no	7.297	7.400	EPSD	ICGC;COSMIC	5.604	Up-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q7Z2Z1	TICRR	O14757	CHEK1	S891	Q896H	896	Missense	distal	5	no	7.297	7.238	EPSD	ICGC	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q7Z2Z1	TICRR	O14757	CHEK1	S891	T886M	886	Missense	distal	-5	no	7.297	4.980	EPSD	ICGC;COSMIC	5.604	Loss
CAMK_CAMKL_CHK1_CHEK1_ST	Q7Z2Z1	TICRR	O14757	CHEK1	S938	G932V	932	Missense	distal	-6	no	11.595	11.569	EPSD	ICGC	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q7Z2Z1	TICRR	O14757	CHEK1	S938	A941S	941	Missense	distal	3	no	11.595	11.501	EPSD	ICGC	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q7Z2Z1	TICRR	O14757	CHEK1	S1026	L1019F	1019	Missense	distal	-7	no	8.434	7.586	EPSD	ICGC	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q7Z2Z1	TICRR	O14757	CHEK1	S1125	P1131L	1131	Missense	distal	6	no	9.804	9.594	EPSD	ICGC;COSMIC	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q7Z2Z1	TICRR	O14757	CHEK1	S1428	P1434S	1434	Missense	distal	6	no	6.687	6.067	EPSD	ICGC;COSMIC	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q7Z2Z1	TICRR	O14757	CHEK1	S1594	S1590G	1590	Missense	distal	-4	no	5.549	5.883	EPSD	ICGC;COSMIC	5.604	Gain
CAMK_CAMKL_CHK1_CHEK1_ST	Q7Z2Z1	TICRR	O14757	CHEK1	S1594	S1600N	1600	Missense	distal	6	no	5.549	5.683	EPSD	ICGC;COSMIC	5.604	Gain
CAMK_CAMKL_CHK1_CHEK1_ST	Q7Z2Z1	TICRR	O14757	CHEK1	S1615	E1618D	1618	Missense	distal	3	no	5.556	5.653	EPSD	ICGC;GDSC;CCLE	5.604	Gain
CAMK_CAMKL_CHK1_CHEK1_ST	Q7Z2Z1	TICRR	O14757	CHEK1	S1714	S1718T	1718	Missense	distal	4	no	7.331	7.342	EPSD	ICGC;COSMIC	5.604	Up-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q7Z2Z1	TICRR	O14757	CHEK1	S1714	A1707S	1707	Missense	distal	-7	no	7.331	6.881	EPSD	ICGC;COSMIC	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q7Z2Z1	TICRR	O14757	CHEK1	S1797	K1801N	1801	Missense	distal	4	no	5.667	5.735	EPSD	ICGC;COSMIC	5.604	Up-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q7Z2Z1	TICRR	O14757	CHEK1	S1806	G1805V	1805	Missense	proximal	-1	no	6.466	6.543	EPSD	ICGC	5.604	Up-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q7Z2Z1	TICRR	O14757	CHEK1	S1806	K1801N	1801	Missense	distal	-5	no	6.466	5.573	EPSD	ICGC;COSMIC	5.604	Loss
CAMK_CAMKL_CHK1_CHEK1_ST	Q9NRL2	BAZ1A	O14757	CHEK1	S601	S602R	602	Missense	proximal	1	no	7.837	7.863	EPSD	ICGC	5.604	Up-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q9NRL2	BAZ1A	O14757	CHEK1	T771	A772D	772	Missense	proximal	1	no	6.558	6.644	EPSD	ICGC	5.604	Up-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q9NRL2	BAZ1A	O14757	CHEK1	S842	P841R	841	Missense	proximal	-1	no	7.148	6.862	EPSD	ICGC	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q9NRL2	BAZ1A	O14757	CHEK1	S960	N962S	962	Missense	proximal	2	no	9.431	9.249	EPSD	ICGC;COSMIC	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q9NRL2	BAZ1A	O14757	CHEK1	S1205	R1200S	1200	Missense	distal	-5	no	9.737	9.526	EPSD	ICGC	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q9NRL2	BAZ1A	O14757	CHEK1	S1206	R1200S	1200	Missense	distal	-6	no	9.311	9.391	EPSD	ICGC	5.604	Up-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q9NRL2	BAZ1A	O14757	CHEK1	S1296	T1302K	1302	Missense	distal	6	no	9.263	8.953	EPSD	ICGC	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q9NRL2	BAZ1A	O14757	CHEK1	S1296	G1292V	1292	Missense	distal	-4	no	9.263	9.229	EPSD	ICGC;COSMIC	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q9NRL2	BAZ1A	O14757	CHEK1	S1320	R1316T	1316	Missense	distal	-4	no	8.923	8.564	PhosphoSitePlus	ICGC;COSMIC	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q9NRL2	BAZ1A	O14757	CHEK1	S1320	P1322T	1322	Missense	proximal	2	no	8.923	8.608	PhosphoSitePlus	ICGC;GDSC	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q9NRL2	BAZ1A	O14757	CHEK1	S1426	R1428Q	1428	Missense	proximal	2	no	10.205	10.734	EPSD	ICGC;COSMIC	5.604	Up-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q9NRL2	BAZ1A	O14757	CHEK1	S1426	R1423G	1423	Missense	distal	-3	no	10.205	2.431	EPSD	ICGC;COSMIC	5.604	Loss
CAMK_CAMKL_CHK1_CHEK1_ST	Q9NRL2	BAZ1A	O14757	CHEK1	S1426	Q1429H	1429	Missense	distal	3	no	10.205	9.174	EPSD	ICGC;COSMIC	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q9NRL2	BAZ1A	O14757	CHEK1	S1492	C1486F	1486	Missense	distal	-6	no	7.983	8.221	EPSD	ICGC;COSMIC	5.604	Up-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q9NRL2	BAZ1A	O14757	CHEK1	S1540	P1539H	1539	Missense	proximal	-1	no	6.375	6.215	EPSD	ICGC;COSMIC	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q9NRL2	BAZ1A	O14757	CHEK1	S1540	T1538K	1538	Missense	proximal	-2	no	6.375	6.039	EPSD	ICGC;COSMIC	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q9NRL2	BAZ1A	O14757	CHEK1	S1540	L1535F	1535	Missense	distal	-5	no	6.375	2.812	EPSD	ICGC	5.604	Loss
CAMK_CAMKL_CHK1_CHEK1_ST	Q9NRL2	BAZ1A	O14757	CHEK1	S1540	H1536N	1536	Missense	distal	-4	no	6.375	6.559	EPSD	ICGC;COSMIC	5.604	Up-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	P54132	BLM	O14757	CHEK1	S33	P30R	30	Missense	distal	-3	no	0.904	8.041	EPSD	ICGC;COSMIC	5.604	Gain
CAMK_CAMKL_CHK1_CHEK1_ST	P54132	BLM	O14757	CHEK1	S72	E69K	69	Missense	distal	-3	no	4.281	7.543	EPSD	ICGC;COSMIC	5.604	Gain
CAMK_CAMKL_CHK1_CHEK1_ST	P54132	BLM	O14757	CHEK1	T182	Q184H	184	Missense	proximal	2	no	10.690	10.180	EPSD;PhosphoSitePlus	ICGC;COSMIC	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	P54132	BLM	O14757	CHEK1	S269	K272N	272	Missense	distal	3	no	9.017	9.215	EPSD	ICGC;COSMIC	5.604	Up-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	P54132	BLM	O14757	CHEK1	S349	E346K	346	Missense	distal	-3	no	4.540	7.803	EPSD	ICGC;COSMIC	5.604	Gain
CAMK_CAMKL_CHK1_CHEK1_ST	P54132	BLM	O14757	CHEK1	S367	Q365L	365	Missense	proximal	-2	no	6.144	6.104	EPSD	ICGC;COSMIC	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	P54132	BLM	O14757	CHEK1	S434	P438S	438	Missense	distal	4	no	7.911	7.771	EPSD	ICGC;COSMIC	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	P54132	BLM	O14757	CHEK1	S597	S601Y	601	Missense	distal	4	no	5.636	5.810	EPSD	ICGC;COSMIC	5.604	Up-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	P54132	BLM	O14757	CHEK1	S602	S601Y	601	Missense	proximal	-1	no	7.824	8.153	EPSD	ICGC;COSMIC	5.604	Up-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	P54132	BLM	O14757	CHEK1	S646	R643H	643	Missense	distal	-3	no	9.083	3.273	EPSD;PhosphoSitePlus	ICGC;COSMIC;GDSC	5.604	Loss
CAMK_CAMKL_CHK1_CHEK1_ST	P54132	BLM	O14757	CHEK1	S646	Q645K	645	Missense	proximal	-1	no	9.083	8.919	EPSD;PhosphoSitePlus	ICGC;COSMIC	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	P54132	BLM	O14757	CHEK1	S646	R643L	643	Missense	distal	-3	no	9.083	-9.464	EPSD;PhosphoSitePlus	ICGC;COSMIC	5.604	Loss
CAMK_CAMKL_CHK1_CHEK1_ST	P54132	BLM	O14757	CHEK1	S646	S648N	648	Missense	proximal	2	no	9.083	9.264	EPSD;PhosphoSitePlus	ICGC	5.604	Up-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	P54132	BLM	O14757	CHEK1	S823	F821S	821	Missense	proximal	-2	no	6.061	5.772	EPSD	ICGC;COSMIC	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	P54132	BLM	O14757	CHEK1	S823	T830M	830	Missense	distal	7	no	6.061	6.113	EPSD	ICGC;COSMIC	5.604	Up-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	P54132	BLM	O14757	CHEK1	S1128	Q1127H	1127	Missense	proximal	-1	no	8.259	8.369	EPSD	ICGC;COSMIC	5.604	Up-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	P54132	BLM	O14757	CHEK1	S1128	S1123G	1123	Missense	distal	-5	no	8.259	8.305	EPSD	ICGC;COSMIC	5.604	Up-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	P54132	BLM	O14757	CHEK1	S1128	G1132E	1132	Missense	distal	4	no	8.259	8.150	EPSD	ICGC	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	P54132	BLM	O14757	CHEK1	S1128	G1129V	1129	Missense	proximal	1	no	8.259	8.235	EPSD	ICGC;COSMIC	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	P54132	BLM	O14757	CHEK1	S1128	A1124T	1124	Missense	distal	-4	no	8.259	7.828	EPSD	ICGC;COSMIC	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	P54132	BLM	O14757	CHEK1	S1254	S1252F	1252	Missense	proximal	-2	no	5.807	6.097	EPSD	ICGC;COSMIC	5.604	Up-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	P54132	BLM	O14757	CHEK1	S1254	A1250S	1250	Missense	distal	-4	no	5.807	5.428	EPSD	ICGC	5.604	Loss
CAMK_CAMKL_CHK1_CHEK1_ST	P54132	BLM	O14757	CHEK1	S1375	S1375G	1375	Missense	central	0	yes	5.848	0.000	EPSD	ICGC	5.604	Loss
CAMK_CAMKL_CHK1_CHEK1_ST	P54132	BLM	O14757	CHEK1	S1375	S1368P	1368	Missense	distal	-7	no	5.848	5.178	EPSD	ICGC;COSMIC	5.604	Loss
CAMK_CAMKL_CHK1_CHEK1_ST	P54132	BLM	O14757	CHEK1	S1375	G1378V	1378	Missense	distal	3	no	5.848	6.274	EPSD	ICGC	5.604	Up-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	O00716	E2F3	O14757	CHEK1	S124	G125S	125	Missense	proximal	1	no	12.407	12.390	PhosphoSitePlus	ICGC;COSMIC	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	O00716	E2F3	O14757	CHEK1	T181	G184C	184	Missense	distal	3	no	8.888	8.026	EPSD	ICGC;COSMIC;CCLE	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	O00716	E2F3	O14757	CHEK1	T181	R178L	178	Missense	distal	-3	no	8.888	-9.658	EPSD	ICGC	5.604	Loss
CAMK_CAMKL_CHK1_CHEK1_ST	O00716	E2F3	O14757	CHEK1	S235	M242L	242	Missense	distal	7	no	8.306	8.314	EPSD	ICGC	5.604	Up-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	O00716	E2F3	O14757	CHEK1	S308	D303H	303	Missense	distal	-5	no	6.273	4.795	EPSD	ICGC;COSMIC	5.604	Loss
CAMK_CAMKL_CHK1_CHEK1_ST	O14757	CHEK1	O14757	CHEK1	S280	P276S	276	Missense	distal	-4	no	10.080	9.843	EPSD	ICGC	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	O14757	CHEK1	O14757	CHEK1	S280	V283L	283	Missense	distal	3	no	10.080	9.307	EPSD	ICGC	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	O14757	CHEK1	O14757	CHEK1	S316	R322L	322	Missense	distal	6	no	5.834	6.156	EPSD;PhosphoSitePlus	ICGC	5.604	Up-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	O14757	CHEK1	O14757	CHEK1	T382	R376I	376	Missense	distal	-6	no	9.696	9.774	EPSD;PhosphoSitePlus	ICGC	5.604	Up-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	O14757	CHEK1	O14757	CHEK1	T382	R379L	379	Missense	distal	-3	no	9.696	-8.851	EPSD;PhosphoSitePlus	ICGC	5.604	Loss
CAMK_CAMKL_CHK1_CHEK1_ST	O14757	CHEK1	O14757	CHEK1	T382	A386S	386	Missense	distal	4	no	9.696	9.502	EPSD;PhosphoSitePlus	ICGC;COSMIC	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	O14757	CHEK1	O14757	CHEK1	T382	M377V	377	Missense	distal	-5	no	9.696	10.592	EPSD;PhosphoSitePlus	ICGC;COSMIC	5.604	Up-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q14669	TRIP12	O14757	CHEK1	T54	N53I	53	Missense	proximal	-1	no	8.431	8.330	EPSD	ICGC;COSMIC	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q14669	TRIP12	O14757	CHEK1	S246	S246F	246	Missense	central	0	yes	8.213	0.000	EPSD	ICGC;COSMIC	5.604	Loss
CAMK_CAMKL_CHK1_CHEK1_ST	Q14669	TRIP12	O14757	CHEK1	S938	P944L	944	Missense	distal	6	no	6.571	6.361	EPSD	ICGC;COSMIC	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q14669	TRIP12	O14757	CHEK1	T1377	P1383T	1383	Missense	distal	6	no	11.435	11.126	EPSD	ICGC;COSMIC	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q9UKI8	TLK1	O14757	CHEK1	S188	S188N	188	Missense	central	0	yes	9.328	0.000	EPSD	ICGC	5.604	Loss
CAMK_CAMKL_CHK1_CHEK1_ST	Q9UKI8	TLK1	O14757	CHEK1	S679	H676Q	676	Missense	distal	-3	no	7.733	6.335	EPSD;PhosphoSitePlus	ICGC	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q9UKI8	TLK1	O14757	CHEK1	S679	Q685R	685	Missense	distal	6	no	7.733	7.740	EPSD;PhosphoSitePlus	ICGC;COSMIC	5.604	Up-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q9UKI8	TLK1	O14757	CHEK1	T688	Q685R	685	Missense	distal	-3	no	3.978	11.185	EPSD	ICGC;COSMIC	5.604	Gain
CAMK_CAMKL_CHK1_CHEK1_ST	P49761	CLK3	O14757	CHEK1	S157	R154P	154	Missense	distal	-3	no	10.275	3.138	PhosphoSitePlus	ICGC	5.604	Loss
CAMK_CAMKL_CHK1_CHEK1_ST	P49761	CLK3	O14757	CHEK1	S173	R172L	172	Missense	proximal	-1	no	8.724	8.824	EPSD	ICGC	5.604	Up-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	P49761	CLK3	O14757	CHEK1	S175	R172L	172	Missense	distal	-3	no	8.264	-10.282	EPSD	ICGC	5.604	Loss
CAMK_CAMKL_CHK1_CHEK1_ST	P49761	CLK3	O14757	CHEK1	S186	P192L	192	Missense	distal	6	no	13.199	12.989	EPSD	ICGC	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	P49761	CLK3	O14757	CHEK1	S197	P192L	192	Missense	distal	-5	no	6.038	10.745	EPSD	ICGC	5.604	Up-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	P49761	CLK3	O14757	CHEK1	S199	P192L	192	Missense	distal	-7	no	9.036	8.822	EPSD	ICGC	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	P49761	CLK3	O14757	CHEK1	S215	D214G	214	Missense	proximal	-1	no	9.322	9.371	EPSD	ICGC;COSMIC	5.604	Up-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	P49761	CLK3	O14757	CHEK1	S215	D216Y	216	Missense	proximal	1	no	9.322	9.200	EPSD	ICGC;COSMIC	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	P49761	CLK3	O14757	CHEK1	S215	S215G	215	Missense	central	0	yes	9.322	0.000	EPSD	ICGC;COSMIC	5.604	Loss
CAMK_CAMKL_CHK1_CHEK1_ST	P49761	CLK3	O14757	CHEK1	S226	S226Y	226	Missense	central	0	yes	9.928	0.000	EPSD	ICGC;COSMIC	5.604	Loss
CAMK_CAMKL_CHK1_CHEK1_ST	P49761	CLK3	O14757	CHEK1	S243	R244W	244	Missense	proximal	1	no	9.239	9.209	EPSD	ICGC;COSMIC	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	P49761	CLK3	O14757	CHEK1	S243	R238W	238	Missense	distal	-5	no	9.239	8.380	EPSD	ICGC	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	P49761	CLK3	O14757	CHEK1	S265	H259Y	259	Missense	distal	-6	no	10.395	10.528	EPSD	ICGC;COSMIC	5.604	Up-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	P49761	CLK3	O14757	CHEK1	S265	S271L	271	Missense	distal	6	no	10.395	10.805	EPSD	ICGC;COSMIC	5.604	Up-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	P49761	CLK3	O14757	CHEK1	S265	S268N	268	Missense	distal	3	no	10.395	11.237	EPSD	ICGC;COSMIC	5.604	Up-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	P49761	CLK3	O14757	CHEK1	S267	S271L	271	Missense	distal	4	no	8.524	8.560	EPSD	ICGC;COSMIC	5.604	Up-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	P49761	CLK3	O14757	CHEK1	S267	S268N	268	Missense	proximal	1	no	8.524	8.521	EPSD	ICGC;COSMIC	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	P49761	CLK3	O14757	CHEK1	S458	E455K	455	Missense	distal	-3	no	3.797	7.060	EPSD	ICGC	5.604	Gain
CAMK_CAMKL_CHK1_CHEK1_ST	P85299	PRR5	O14757	CHEK1	S240	L235P	235	Missense	distal	-5	no	12.950	8.244	PhosphoSitePlus	ICGC;COSMIC	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	O75461	E2F6	O14757	CHEK1	S12	K9R	9	Missense	distal	-3	no	1.824	5.649	EPSD;PhosphoSitePlus	ICGC	5.604	Gain
CAMK_CAMKL_CHK1_CHEK1_ST	P04637	TP53	O14757	CHEK1	S37	P34L	34	Missense	distal	-3	no	8.422	-2.988	PhosphoSitePlus;EPSD	ICGC;COSMIC	5.604	Loss
CAMK_CAMKL_CHK1_CHEK1_ST	P04637	TP53	O14757	CHEK1	S37	S33F	33	Missense	distal	-4	no	8.422	8.180	PhosphoSitePlus;EPSD	ICGC;COSMIC	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	P04637	TP53	O14757	CHEK1	S37	N30I	30	Missense	distal	-7	no	8.422	8.317	PhosphoSitePlus;EPSD	ICGC	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	P04637	TP53	O14757	CHEK1	S127	C124R	124	Missense	distal	-3	no	2.181	10.272	EPSD	ICGC;COSMIC;GDSC;CCLE	5.604	Gain
CAMK_CAMKL_CHK1_CHEK1_ST	P04637	TP53	O14757	CHEK1	T155	P152R	152	Missense	distal	-3	no	1.584	8.721	EPSD	ICGC;COSMIC	5.604	Gain
CAMK_CAMKL_CHK1_CHEK1_ST	P04637	TP53	O14757	CHEK1	S269	V272E	272	Missense	distal	3	no	5.247	6.369	EPSD	ICGC;COSMIC;CCLE	5.604	Gain
CAMK_CAMKL_CHK1_CHEK1_ST	O15350	TP73	O14757	CHEK1	S47	G44R	44	Missense	distal	-3	no	2.161	9.936	PhosphoSitePlus	ICGC;COSMIC;GDSC;CCLE	5.604	Gain
CAMK_CAMKL_CHK1_CHEK1_ST	O15350	TP73	O14757	CHEK1	S326	G323R	323	Missense	distal	-3	no	3.395	11.170	EPSD	ICGC;COSMIC	5.604	Gain
CAMK_CAMKL_CHK1_CHEK1_ST	O15350	TP73	O14757	CHEK1	S426	M421I	421	Missense	distal	-5	no	6.018	8.360	EPSD	ICGC;COSMIC	5.604	Up-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	O15350	TP73	O14757	CHEK1	S426	G432V	432	Missense	distal	6	no	6.018	6.081	EPSD	ICGC	5.604	Up-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	O15350	TP73	O14757	CHEK1	S426	G432D	432	Missense	distal	6	no	6.018	5.622	EPSD	ICGC;COSMIC;GDSC;CCLE	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q12789	GTF3C1	O14757	CHEK1	S58	P55R	55	Missense	distal	-3	no	2.169	9.306	EPSD	ICGC;COSMIC	5.604	Gain
CAMK_CAMKL_CHK1_CHEK1_ST	Q12789	GTF3C1	O14757	CHEK1	S267	T270N	270	Missense	distal	3	no	4.704	5.689	EPSD	ICGC	5.604	Gain
CAMK_CAMKL_CHK1_CHEK1_ST	Q12789	GTF3C1	O14757	CHEK1	S480	E483D	483	Missense	distal	3	no	6.209	6.307	EPSD	ICGC;COSMIC	5.604	Up-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q12789	GTF3C1	O14757	CHEK1	T508	P510L	510	Missense	proximal	2	no	7.593	7.276	EPSD	ICGC	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q12789	GTF3C1	O14757	CHEK1	T508	A502T	502	Missense	distal	-6	no	7.593	7.789	EPSD	ICGC	5.604	Up-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q12789	GTF3C1	O14757	CHEK1	T508	P515Q	515	Missense	distal	7	no	7.593	7.785	EPSD	ICGC;COSMIC	5.604	Up-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q12789	GTF3C1	O14757	CHEK1	T508	P506T	506	Missense	proximal	-2	no	7.593	7.563	EPSD	ICGC;COSMIC	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q12789	GTF3C1	O14757	CHEK1	S560	S557R	557	Missense	distal	-3	no	-3.303	6.393	EPSD	ICGC	5.604	Gain
CAMK_CAMKL_CHK1_CHEK1_ST	Q12789	GTF3C1	O14757	CHEK1	S603	G599W	599	Missense	distal	-4	no	11.942	11.154	EPSD	ICGC;COSMIC	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q12789	GTF3C1	O14757	CHEK1	S603	G604D	604	Missense	proximal	1	no	11.942	12.030	EPSD	ICGC	5.604	Up-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q12789	GTF3C1	O14757	CHEK1	S667	N665K	665	Missense	proximal	-2	no	13.699	13.428	PhosphoSitePlus	ICGC	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q12789	GTF3C1	O14757	CHEK1	S695	D697E	697	Missense	proximal	2	no	7.572	7.654	EPSD	ICGC	5.604	Up-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q12789	GTF3C1	O14757	CHEK1	S695	N699K	699	Missense	distal	4	no	7.572	7.504	EPSD	ICGC	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q12789	GTF3C1	O14757	CHEK1	S695	S695F	695	Missense	central	0	yes	7.572	0.000	EPSD	ICGC;COSMIC	5.604	Loss
CAMK_CAMKL_CHK1_CHEK1_ST	Q12789	GTF3C1	O14757	CHEK1	T725	S718R	718	Missense	distal	-7	no	7.270	7.010	EPSD	ICGC	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q12789	GTF3C1	O14757	CHEK1	S761	K765I	765	Missense	distal	4	no	7.852	7.951	EPSD	ICGC;COSMIC	5.604	Up-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q12789	GTF3C1	O14757	CHEK1	S836	R830I	830	Missense	distal	-6	no	7.266	7.345	EPSD	ICGC;COSMIC	5.604	Up-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q12789	GTF3C1	O14757	CHEK1	S836	Q834H	834	Missense	proximal	-2	no	7.266	7.284	EPSD	ICGC;COSMIC	5.604	Up-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q12789	GTF3C1	O14757	CHEK1	S836	G840D	840	Missense	distal	4	no	7.266	7.249	EPSD	ICGC;COSMIC	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q12789	GTF3C1	O14757	CHEK1	S836	R829W	829	Missense	distal	-7	no	7.266	5.720	EPSD	ICGC;COSMIC	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q12789	GTF3C1	O14757	CHEK1	S845	G840D	840	Missense	distal	-5	no	6.410	5.588	EPSD	ICGC;COSMIC	5.604	Loss
CAMK_CAMKL_CHK1_CHEK1_ST	Q12789	GTF3C1	O14757	CHEK1	S1062	Q1066H	1066	Missense	distal	4	no	11.732	11.894	EPSD	ICGC;COSMIC	5.604	Up-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q12789	GTF3C1	O14757	CHEK1	S1062	V1058I	1058	Missense	distal	-4	no	11.732	11.452	EPSD	ICGC;COSMIC	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q12789	GTF3C1	O14757	CHEK1	S1063	Q1066H	1066	Missense	distal	3	no	7.279	6.248	EPSD	ICGC;COSMIC	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q12789	GTF3C1	O14757	CHEK1	S1063	V1058I	1058	Missense	distal	-5	no	7.279	8.725	EPSD	ICGC;COSMIC	5.604	Up-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q12789	GTF3C1	O14757	CHEK1	T1146	A1141T	1141	Missense	distal	-5	no	4.901	8.761	EPSD	ICGC;COSMIC	5.604	Gain
CAMK_CAMKL_CHK1_CHEK1_ST	Q12789	GTF3C1	O14757	CHEK1	T1158	Q1157L	1157	Missense	proximal	-1	no	9.378	9.462	EPSD	ICGC;COSMIC	5.604	Up-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q12789	GTF3C1	O14757	CHEK1	S1173	S1168N	1168	Missense	distal	-5	no	9.124	9.617	EPSD	ICGC	5.604	Up-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q12789	GTF3C1	O14757	CHEK1	S1173	A1169D	1169	Missense	distal	-4	no	9.124	9.115	EPSD	ICGC	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q12789	GTF3C1	O14757	CHEK1	S1173	I1177S	1177	Missense	distal	4	no	9.124	9.072	EPSD	ICGC;COSMIC	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q12789	GTF3C1	O14757	CHEK1	S1379	A1381T	1381	Missense	proximal	2	no	7.706	6.858	EPSD	ICGC;COSMIC	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q12789	GTF3C1	O14757	CHEK1	S1380	A1381T	1381	Missense	proximal	1	no	10.872	10.861	EPSD	ICGC;COSMIC	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q12789	GTF3C1	O14757	CHEK1	S1611	S1611N	1611	Missense	central	0	yes	9.591	0.000	EPSD	ICGC	5.604	Loss
CAMK_CAMKL_CHK1_CHEK1_ST	Q12789	GTF3C1	O14757	CHEK1	S1611	D1609E	1609	Missense	proximal	-2	no	9.591	9.605	EPSD	ICGC	5.604	Up-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q12789	GTF3C1	O14757	CHEK1	S1611	D1615Y	1615	Missense	distal	4	no	9.591	9.715	EPSD	ICGC	5.604	Up-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q12789	GTF3C1	O14757	CHEK1	S1611	G1610S	1610	Missense	proximal	-1	no	9.591	9.412	EPSD	ICGC;COSMIC	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q12789	GTF3C1	O14757	CHEK1	S1767	K1771T	1771	Missense	distal	4	no	13.121	13.180	EPSD	ICGC	5.604	Up-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q12789	GTF3C1	O14757	CHEK1	S1767	R1763C	1763	Missense	distal	-4	no	13.121	12.748	EPSD	ICGC;COSMIC	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q12789	GTF3C1	O14757	CHEK1	S1767	K1771N	1771	Missense	distal	4	no	13.121	13.189	EPSD	ICGC;COSMIC	5.604	Up-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q12789	GTF3C1	O14757	CHEK1	S1767	E1760K	1760	Missense	distal	-7	no	13.121	13.819	EPSD	ICGC	5.604	Up-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q12789	GTF3C1	O14757	CHEK1	S1842	E1848G	1848	Missense	distal	6	no	7.120	7.602	EPSD	ICGC;COSMIC	5.604	Up-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q5T8P6	RBM26	O14757	CHEK1	S176	S180R	180	Missense	distal	4	no	8.076	8.127	EPSD	ICGC;COSMIC	5.604	Up-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q5T8P6	RBM26	O14757	CHEK1	S176	R177H	177	Missense	proximal	1	no	8.076	8.011	EPSD	ICGC;COSMIC;GDSC;CCLE	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q5T8P6	RBM26	O14757	CHEK1	S178	S180R	180	Missense	proximal	2	no	11.077	10.982	EPSD	ICGC;COSMIC	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q5T8P6	RBM26	O14757	CHEK1	S178	R177H	177	Missense	proximal	-1	no	11.077	11.203	EPSD	ICGC;COSMIC;GDSC;CCLE	5.604	Up-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q5T8P6	RBM26	O14757	CHEK1	S180	S180R	180	Missense	central	0	yes	10.411	0.000	EPSD	ICGC;COSMIC	5.604	Loss
CAMK_CAMKL_CHK1_CHEK1_ST	Q5T8P6	RBM26	O14757	CHEK1	S180	R177H	177	Missense	distal	-3	no	10.411	4.602	EPSD	ICGC;COSMIC;GDSC;CCLE	5.604	Loss
CAMK_CAMKL_CHK1_CHEK1_ST	Q5T8P6	RBM26	O14757	CHEK1	S184	S180R	180	Missense	distal	-4	no	9.977	10.285	EPSD	ICGC;COSMIC	5.604	Up-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q5T8P6	RBM26	O14757	CHEK1	S184	R177H	177	Missense	distal	-7	no	9.977	9.918	EPSD	ICGC;COSMIC;GDSC;CCLE	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q5T8P6	RBM26	O14757	CHEK1	S186	S180R	180	Missense	distal	-6	no	9.794	9.714	EPSD	ICGC;COSMIC	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q5T8P6	RBM26	O14757	CHEK1	S518	R515T	515	Missense	distal	-3	no	7.708	-12.861	EPSD	ICGC;COSMIC	5.604	Loss
CAMK_CAMKL_CHK1_CHEK1_ST	Q5T8P6	RBM26	O14757	CHEK1	S608	L612F	612	Missense	distal	4	no	7.751	7.813	EPSD	ICGC;COSMIC	5.604	Up-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	P16989	YBX3	O14757	CHEK1	S79	A74V	74	Missense	distal	-5	no	3.811	6.250	EPSD	ICGC;COSMIC	5.604	Gain
CAMK_CAMKL_CHK1_CHEK1_ST	P16989	YBX3	O14757	CHEK1	T112	G105R	105	Missense	distal	-7	no	11.798	11.759	PhosphoSitePlus	ICGC;COSMIC	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	P16989	YBX3	O14757	CHEK1	S203	E197K	197	Missense	distal	-6	no	6.827	6.859	EPSD	ICGC;COSMIC	5.604	Up-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	P16989	YBX3	O14757	CHEK1	S217	R220L	220	Missense	distal	3	no	9.466	9.035	EPSD	ICGC	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	P16989	YBX3	O14757	CHEK1	T286	V281G	281	Missense	distal	-5	no	6.117	6.451	EPSD	ICGC;COSMIC	5.604	Up-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	P16989	YBX3	O14757	CHEK1	S293	P296H	296	Missense	distal	3	no	11.199	10.897	EPSD	ICGC	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q27J81	INF2	O14757	CHEK1	S129	R126H	126	Missense	distal	-3	no	9.006	3.197	EPSD	ICGC;COSMIC	5.604	Loss
CAMK_CAMKL_CHK1_CHEK1_ST	Q27J81	INF2	O14757	CHEK1	S343	P350L	350	Missense	distal	7	no	10.055	9.992	EPSD	ICGC;COSMIC	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q27J81	INF2	O14757	CHEK1	S343	E339Q	339	Missense	distal	-4	no	10.055	10.011	EPSD	ICGC;COSMIC	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q27J81	INF2	O14757	CHEK1	S419	P423S	423	Missense	distal	4	no	5.708	5.568	EPSD	ICGC;COSMIC	5.604	Loss
CAMK_CAMKL_CHK1_CHEK1_ST	Q27J81	INF2	O14757	CHEK1	S586	A585V	585	Missense	proximal	-1	no	7.871	7.793	EPSD	ICGC;COSMIC	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q27J81	INF2	O14757	CHEK1	S607	R604Q	604	Missense	distal	-3	no	8.081	0.874	EPSD	ICGC;COSMIC;GDSC;CCLE	5.604	Loss
CAMK_CAMKL_CHK1_CHEK1_ST	Q27J81	INF2	O14757	CHEK1	S607	S600F	600	Missense	distal	-7	no	8.081	6.349	EPSD	ICGC	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q27J81	INF2	O14757	CHEK1	S855	S855F	855	Missense	central	0	yes	12.364	0.000	EPSD	ICGC;COSMIC	5.604	Loss
CAMK_CAMKL_CHK1_CHEK1_ST	Q27J81	INF2	O14757	CHEK1	S855	A856T	856	Missense	proximal	1	no	12.364	12.353	EPSD	ICGC;COSMIC	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q27J81	INF2	O14757	CHEK1	S855	E849G	849	Missense	distal	-6	no	12.364	12.523	EPSD	ICGC	5.604	Up-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q27J81	INF2	O14757	CHEK1	S1042	T1039R	1039	Missense	distal	-3	no	-12.637	7.931	EPSD	ICGC;COSMIC	5.604	Gain
CAMK_CAMKL_CHK1_CHEK1_ST	Q27J81	INF2	O14757	CHEK1	S1077	A1082S	1082	Missense	distal	5	no	12.154	12.136	EPSD	ICGC	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q27J81	INF2	O14757	CHEK1	S1194	D1196V	1196	Missense	proximal	2	no	8.336	7.763	EPSD	ICGC;COSMIC	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q27J81	INF2	O14757	CHEK1	S1194	A1197S	1197	Missense	distal	3	no	8.336	8.242	EPSD	ICGC	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q27J81	INF2	O14757	CHEK1	S1227	E1232D	1232	Missense	distal	5	no	9.118	9.119	EPSD	ICGC	5.604	Up-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q27J81	INF2	O14757	CHEK1	S1229	E1232D	1232	Missense	distal	3	no	6.137	6.235	EPSD	ICGC	5.604	Up-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	P30304	CDC25A	O14757	CHEK1	S107	S107Y	107	Missense	central	0	yes	7.848	0.000	EPSD	ICGC	5.604	Loss
CAMK_CAMKL_CHK1_CHEK1_ST	P30304	CDC25A	O14757	CHEK1	S124	H129Q	129	Missense	distal	5	no	10.290	10.349	EPSD;PhosphoSitePlus	ICGC	5.604	Up-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	P30304	CDC25A	O14757	CHEK1	S124	P117Q	117	Missense	distal	-7	no	10.290	10.958	EPSD;PhosphoSitePlus	ICGC	5.604	Up-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	P30304	CDC25A	O14757	CHEK1	S178	L184I	184	Missense	distal	6	no	11.553	11.186	EPSD;PhosphoSitePlus	ICGC	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	P30304	CDC25A	O14757	CHEK1	S505	R506Q	506	Missense	proximal	1	no	7.469	7.477	EPSD	ICGC;COSMIC	5.604	Up-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	P30304	CDC25A	O14757	CHEK1	S505	R502C	502	Missense	distal	-3	no	7.469	-0.623	EPSD	ICGC	5.604	Loss
CAMK_CAMKL_CHK1_CHEK1_ST	P30304	CDC25A	O14757	CHEK1	T507	R506Q	506	Missense	proximal	-1	no	6.453	6.468	EPSD;PhosphoSitePlus	ICGC;COSMIC	5.604	Up-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	P30304	CDC25A	O14757	CHEK1	T507	R502C	502	Missense	distal	-5	no	6.453	5.775	EPSD;PhosphoSitePlus	ICGC	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	P46013	MKI67	O14757	CHEK1	T109	N104S	104	Missense	distal	-5	no	7.616	7.123	EPSD	ICGC;COSMIC	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	P46013	MKI67	O14757	CHEK1	T109	R116C	116	Missense	distal	7	no	7.616	7.210	EPSD	ICGC	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	P46013	MKI67	O14757	CHEK1	T109	P112S	112	Missense	distal	3	no	7.616	7.286	EPSD	ICGC	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	P46013	MKI67	O14757	CHEK1	S125	R126S	126	Missense	proximal	1	no	7.054	7.028	EPSD	ICGC	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	P46013	MKI67	O14757	CHEK1	S125	R123C	123	Missense	proximal	-2	no	7.054	7.003	EPSD	ICGC	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	P46013	MKI67	O14757	CHEK1	S125	D132E	132	Missense	distal	7	no	7.054	6.997	EPSD	ICGC	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	P46013	MKI67	O14757	CHEK1	S125	R122H	122	Missense	distal	-3	no	7.054	1.245	EPSD	ICGC;COSMIC;GDSC;CCLE	5.604	Loss
CAMK_CAMKL_CHK1_CHEK1_ST	P46013	MKI67	O14757	CHEK1	S125	S130Y	130	Missense	distal	5	no	7.054	6.600	EPSD	ICGC;COSMIC	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	P46013	MKI67	O14757	CHEK1	S296	R290H	290	Missense	distal	-6	no	11.621	11.730	EPSD	ICGC;COSMIC	5.604	Up-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	P46013	MKI67	O14757	CHEK1	S296	A302T	302	Missense	distal	6	no	11.621	11.543	EPSD	ICGC;COSMIC	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	P46013	MKI67	O14757	CHEK1	S374	R372L	372	Missense	proximal	-2	no	7.227	7.233	EPSD	ICGC;COSMIC	5.604	Up-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	P46013	MKI67	O14757	CHEK1	S374	R372Q	372	Missense	proximal	-2	no	7.227	7.273	EPSD	ICGC	5.604	Up-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	P46013	MKI67	O14757	CHEK1	T391	R393G	393	Missense	proximal	2	no	5.729	5.759	EPSD	ICGC;COSMIC	5.604	Up-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	P46013	MKI67	O14757	CHEK1	T391	R393K	393	Missense	proximal	2	no	5.729	6.415	EPSD	ICGC;COSMIC	5.604	Up-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	P46013	MKI67	O14757	CHEK1	T391	D387V	387	Missense	distal	-4	no	5.729	5.659	EPSD	ICGC;COSMIC	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	P46013	MKI67	O14757	CHEK1	S396	R393G	393	Missense	distal	-3	no	9.227	1.453	EPSD	ICGC;COSMIC	5.604	Loss
CAMK_CAMKL_CHK1_CHEK1_ST	P46013	MKI67	O14757	CHEK1	S396	R393K	393	Missense	distal	-3	no	9.227	5.402	EPSD	ICGC;COSMIC	5.604	Loss
CAMK_CAMKL_CHK1_CHEK1_ST	P46013	MKI67	O14757	CHEK1	S396	P402Q	402	Missense	distal	6	no	9.227	8.689	EPSD	ICGC	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	P46013	MKI67	O14757	CHEK1	S396	A403V	403	Missense	distal	7	no	9.227	9.307	EPSD	ICGC;COSMIC	5.604	Up-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	P46013	MKI67	O14757	CHEK1	T401	P402Q	402	Missense	proximal	1	no	9.023	9.095	EPSD	ICGC	5.604	Up-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	P46013	MKI67	O14757	CHEK1	T401	R400Q	400	Missense	proximal	-1	no	9.023	9.039	EPSD	ICGC;COSMIC;GDSC;CCLE	5.604	Up-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	P46013	MKI67	O14757	CHEK1	T401	A403V	403	Missense	proximal	2	no	9.023	8.461	EPSD	ICGC;COSMIC	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	P46013	MKI67	O14757	CHEK1	S563	E570K	570	Missense	distal	7	no	6.510	6.344	EPSD	ICGC;COSMIC	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	P46013	MKI67	O14757	CHEK1	S563	E570D	570	Missense	distal	7	no	6.510	6.568	EPSD	ICGC;COSMIC	5.604	Up-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	P46013	MKI67	O14757	CHEK1	T694	T694K	694	Missense	central	0	yes	10.172	0.000	EPSD	ICGC	5.604	Loss
CAMK_CAMKL_CHK1_CHEK1_ST	P46013	MKI67	O14757	CHEK1	T1764	R1760W	1760	Missense	distal	-4	no	9.501	8.739	PhosphoSitePlus	ICGC;COSMIC	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	P46013	MKI67	O14757	CHEK1	T1943	A1950S	1950	Missense	distal	7	no	9.129	9.079	EPSD	ICGC;COSMIC	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q14186	TFDP1	O14757	CHEK1	S120	K122N	122	Missense	proximal	2	no	9.814	9.405	EPSD	ICGC	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q14186	TFDP1	O14757	CHEK1	S120	S120F	120	Missense	central	0	yes	9.814	0.000	EPSD	ICGC	5.604	Loss
CAMK_CAMKL_CHK1_CHEK1_ST	Q14186	TFDP1	O14757	CHEK1	S120	K114R	114	Missense	distal	-6	no	9.814	9.824	EPSD	ICGC	5.604	Up-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q14186	TFDP1	O14757	CHEK1	T132	G131W	131	Missense	proximal	-1	no	6.695	6.795	EPSD	ICGC;COSMIC	5.604	Up-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q14186	TFDP1	O14757	CHEK1	T133	G131W	131	Missense	proximal	-2	no	7.856	7.943	EPSD	ICGC;COSMIC	5.604	Up-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q14186	TFDP1	O14757	CHEK1	S147	A149V	149	Missense	proximal	2	no	8.124	7.562	EPSD	ICGC;COSMIC	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q14186	TFDP1	O14757	CHEK1	S147	D150Y	150	Missense	distal	3	no	8.124	5.339	EPSD	ICGC;COSMIC	5.604	Loss
CAMK_CAMKL_CHK1_CHEK1_ST	Q14186	TFDP1	O14757	CHEK1	S147	V143F	143	Missense	distal	-4	no	8.124	7.582	EPSD	ICGC	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q14186	TFDP1	O14757	CHEK1	S147	E141K	141	Missense	distal	-6	no	8.124	8.156	EPSD	ICGC	5.604	Up-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q9UJM3	ERRFI1	O14757	CHEK1	S334	N329S	329	Missense	distal	-5	no	8.988	8.495	EPSD	ICGC	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q9UJM3	ERRFI1	O14757	CHEK1	S334	P333L	333	Missense	proximal	-1	no	8.988	8.801	EPSD	ICGC	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q9UJM3	ERRFI1	O14757	CHEK1	S369	S369R	369	Missense	central	0	yes	11.718	0.000	EPSD	ICGC	5.604	Loss
CAMK_CAMKL_CHK1_CHEK1_ST	Q9UJM3	ERRFI1	O14757	CHEK1	S372	S369R	369	Missense	distal	-3	no	-0.128	9.568	EPSD	ICGC	5.604	Gain
CAMK_CAMKL_CHK1_CHEK1_ST	Q9BXW9	FANCD2	O14757	CHEK1	S8	S3T	3	Missense	distal	-5	no	8.107	9.239	EPSD	ICGC	5.604	Up-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q9BXW9	FANCD2	O14757	CHEK1	S8	R6I	6	Missense	proximal	-2	no	8.107	8.136	EPSD	ICGC;COSMIC	5.604	Up-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q9BXW9	FANCD2	O14757	CHEK1	S717	Q718E	718	Missense	proximal	1	no	5.613	5.679	EPSD	ICGC	5.604	Up-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q9BXW9	FANCD2	O14757	CHEK1	S717	G721V	721	Missense	distal	4	no	5.613	5.657	EPSD	ICGC	5.604	Up-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q9BXW9	FANCD2	O14757	CHEK1	S717	D711E	711	Missense	distal	-6	no	5.613	5.663	EPSD	ICGC;COSMIC	5.604	Up-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q9BXW9	FANCD2	O14757	CHEK1	S717	S720L	720	Missense	distal	3	no	5.613	5.179	EPSD	ICGC	5.604	Loss
CAMK_CAMKL_CHK1_CHEK1_ST	Q9BXW9	FANCD2	O14757	CHEK1	S978	A985S	985	Missense	distal	7	no	5.665	5.616	EPSD	ICGC	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q9BXW9	FANCD2	O14757	CHEK1	S978	L980V	980	Missense	proximal	2	no	5.665	5.952	EPSD	ICGC;COSMIC	5.604	Up-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q9BXW9	FANCD2	O14757	CHEK1	S978	P982L	982	Missense	distal	4	no	5.665	5.561	EPSD	ICGC	5.604	Loss
CAMK_CAMKL_CHK1_CHEK1_ST	Q9BXW9	FANCD2	O14757	CHEK1	S1195	E1194G	1194	Missense	proximal	-1	no	7.106	7.213	EPSD	ICGC;COSMIC	5.604	Up-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q9UKM9	RALY	O14757	CHEK1	S106	G111C	111	Missense	distal	5	no	14.696	14.540	EPSD	ICGC	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q12888	TP53BP1	O14757	CHEK1	S287	L284R	284	Missense	distal	-3	no	-9.101	9.446	EPSD	ICGC;COSMIC	5.604	Gain
CAMK_CAMKL_CHK1_CHEK1_ST	Q12888	TP53BP1	O14757	CHEK1	T804	E799D	799	Missense	distal	-5	no	6.551	6.951	EPSD	ICGC;COSMIC	5.604	Up-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q12888	TP53BP1	O14757	CHEK1	T804	E806G	806	Missense	proximal	2	no	6.551	5.937	EPSD	ICGC;COSMIC	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q12888	TP53BP1	O14757	CHEK1	T1012	S1019F	1019	Missense	distal	7	no	6.883	6.452	EPSD	ICGC;COSMIC	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q12888	TP53BP1	O14757	CHEK1	T1012	S1019T	1019	Missense	distal	7	no	6.883	6.816	EPSD	ICGC;COSMIC	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q12888	TP53BP1	O14757	CHEK1	T1012	L1007P	1007	Missense	distal	-5	no	6.883	2.176	EPSD	ICGC	5.604	Loss
CAMK_CAMKL_CHK1_CHEK1_ST	Q12888	TP53BP1	O14757	CHEK1	T1012	E1008K	1008	Missense	distal	-4	no	6.883	6.780	EPSD	ICGC	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q12888	TP53BP1	O14757	CHEK1	S1034	I1039M	1039	Missense	distal	5	no	6.117	6.148	EPSD	ICGC;COSMIC	5.604	Up-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q12888	TP53BP1	O14757	CHEK1	S1034	A1027S	1027	Missense	distal	-7	no	6.117	5.667	EPSD	ICGC;COSMIC	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q12888	TP53BP1	O14757	CHEK1	S1034	S1037I	1037	Missense	distal	3	no	6.117	5.742	EPSD	ICGC;COSMIC	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q12888	TP53BP1	O14757	CHEK1	S1067	E1073D	1073	Missense	distal	6	no	6.563	6.650	EPSD	ICGC;COSMIC	5.604	Up-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q12888	TP53BP1	O14757	CHEK1	S1067	P1066Q	1066	Missense	proximal	-1	no	6.563	6.293	EPSD	ICGC;COSMIC	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q12888	TP53BP1	O14757	CHEK1	S1148	E1145K	1145	Missense	distal	-3	no	5.530	8.793	EPSD	ICGC;COSMIC	5.604	Gain
CAMK_CAMKL_CHK1_CHEK1_ST	Q12888	TP53BP1	O14757	CHEK1	S1148	G1153V	1153	Missense	distal	5	no	5.530	5.636	EPSD	ICGC;COSMIC	5.604	Gain
CAMK_CAMKL_CHK1_CHEK1_ST	Q12888	TP53BP1	O14757	CHEK1	S1160	M1157R	1157	Missense	distal	-3	no	2.482	7.631	EPSD	ICGC;COSMIC	5.604	Gain
CAMK_CAMKL_CHK1_CHEK1_ST	Q12888	TP53BP1	O14757	CHEK1	S1208	S1202R	1202	Missense	distal	-6	no	7.549	7.468	EPSD	ICGC	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q12888	TP53BP1	O14757	CHEK1	S1208	G1211W	1211	Missense	distal	3	no	7.549	7.496	EPSD	ICGC;COSMIC	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q12888	TP53BP1	O14757	CHEK1	S1208	A1209V	1209	Missense	proximal	1	no	7.549	7.524	EPSD	ICGC;COSMIC	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q12888	TP53BP1	O14757	CHEK1	T1270	R1267I	1267	Missense	distal	-3	no	8.486	-0.272	EPSD	ICGC;COSMIC	5.604	Loss
CAMK_CAMKL_CHK1_CHEK1_ST	Q12888	TP53BP1	O14757	CHEK1	T1270	E1266K	1266	Missense	distal	-4	no	8.486	8.384	EPSD	ICGC;COSMIC	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q12888	TP53BP1	O14757	CHEK1	T1270	E1264D	1264	Missense	distal	-6	no	8.486	8.436	EPSD	ICGC;COSMIC	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q12888	TP53BP1	O14757	CHEK1	S1317	L1321F	1321	Missense	distal	4	no	11.275	11.336	EPSD	ICGC;COSMIC	5.604	Up-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q12888	TP53BP1	O14757	CHEK1	S1317	S1310P	1310	Missense	distal	-7	no	11.275	10.605	EPSD	ICGC;COSMIC	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q12888	TP53BP1	O14757	CHEK1	S1317	L1321I	1321	Missense	distal	4	no	11.275	11.290	EPSD	ICGC;COSMIC	5.604	Up-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q12888	TP53BP1	O14757	CHEK1	S1317	G1318R	1318	Missense	proximal	1	no	11.275	11.283	EPSD	ICGC;COSMIC	5.604	Up-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q12888	TP53BP1	O14757	CHEK1	S1430	S1430P	1430	Missense	central	0	yes	6.504	0.000	EPSD	ICGC;COSMIC	5.604	Loss
CAMK_CAMKL_CHK1_CHEK1_ST	Q12888	TP53BP1	O14757	CHEK1	S1430	D1424E	1424	Missense	distal	-6	no	6.504	6.554	EPSD	ICGC	5.604	Up-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q12888	TP53BP1	O14757	CHEK1	S1430	D1432N	1432	Missense	proximal	2	no	6.504	6.220	EPSD	ICGC;COSMIC	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q12888	TP53BP1	O14757	CHEK1	S1462	G1455D	1455	Missense	distal	-7	no	11.811	11.802	EPSD	ICGC;COSMIC	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q12888	TP53BP1	O14757	CHEK1	S1462	R1458C	1458	Missense	distal	-4	no	11.811	11.437	EPSD	ICGC;COSMIC	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q12888	TP53BP1	O14757	CHEK1	S1462	P1466S	1466	Missense	distal	4	no	11.811	11.671	EPSD	ICGC;COSMIC	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q12888	TP53BP1	O14757	CHEK1	S1462	R1459H	1459	Missense	distal	-3	no	11.811	6.002	EPSD	ICGC;COSMIC	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q12888	TP53BP1	O14757	CHEK1	S1631	P1636S	1636	Missense	distal	5	no	8.527	8.609	EPSD	ICGC;COSMIC	5.604	Up-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q12888	TP53BP1	O14757	CHEK1	S1631	R1627L	1627	Missense	distal	-4	no	8.527	8.271	EPSD	ICGC;COSMIC	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q12888	TP53BP1	O14757	CHEK1	T1672	R1668I	1668	Missense	distal	-4	no	7.063	6.775	EPSD	ICGC;COSMIC	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q12888	TP53BP1	O14757	CHEK1	T1672	S1665L	1665	Missense	distal	-7	no	7.063	6.178	EPSD	ICGC;COSMIC	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q12888	TP53BP1	O14757	CHEK1	T1672	E1676K	1676	Missense	distal	4	no	7.063	7.057	EPSD	ICGC;COSMIC	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q12888	TP53BP1	O14757	CHEK1	T1672	R1677W	1677	Missense	distal	5	no	7.063	6.894	EPSD	ICGC;COSMIC	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q12888	TP53BP1	O14757	CHEK1	T1672	R1677Q	1677	Missense	distal	5	no	7.063	7.138	EPSD	ICGC;COSMIC	5.604	Up-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q12888	TP53BP1	O14757	CHEK1	S1853	G1851R	1851	Missense	proximal	-2	no	5.803	5.770	EPSD	ICGC;COSMIC	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q12888	TP53BP1	O14757	CHEK1	S1853	E1855K	1855	Missense	proximal	2	no	5.803	5.845	EPSD	ICGC;COSMIC	5.604	Up-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q12888	TP53BP1	O14757	CHEK1	S1853	I1859V	1859	Missense	distal	6	no	5.803	6.037	EPSD	ICGC;COSMIC	5.604	Up-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q12888	TP53BP1	O14757	CHEK1	S1853	Q1857K	1857	Missense	distal	4	no	5.803	5.706	EPSD	ICGC	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q12888	TP53BP1	O14757	CHEK1	S1853	L1848F	1848	Missense	distal	-5	no	5.803	2.240	EPSD	ICGC;COSMIC	5.604	Loss
CAMK_CAMKL_CHK1_CHEK1_ST	Q14966	ZNF638	O14757	CHEK1	S36	F42C	42	Missense	distal	6	no	9.476	9.455	EPSD	ICGC;COSMIC	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q14966	ZNF638	O14757	CHEK1	S36	P40Q	40	Missense	distal	4	no	9.476	9.386	EPSD	ICGC;COSMIC	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q14966	ZNF638	O14757	CHEK1	S488	R495H	495	Missense	distal	7	no	10.760	10.467	EPSD	ICGC;COSMIC	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q14966	ZNF638	O14757	CHEK1	S488	R495L	495	Missense	distal	7	no	10.760	10.660	EPSD	ICGC	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q14966	ZNF638	O14757	CHEK1	S488	S492I	492	Missense	distal	4	no	10.760	10.812	EPSD	ICGC	5.604	Up-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q14966	ZNF638	O14757	CHEK1	S490	R495H	495	Missense	distal	5	no	8.142	8.158	EPSD	ICGC;COSMIC	5.604	Up-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q14966	ZNF638	O14757	CHEK1	S490	R495L	495	Missense	distal	5	no	8.142	8.002	EPSD	ICGC	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q14966	ZNF638	O14757	CHEK1	S490	S492I	492	Missense	proximal	2	no	8.142	7.636	EPSD	ICGC	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q14966	ZNF638	O14757	CHEK1	S500	R495H	495	Missense	distal	-5	no	9.280	6.815	EPSD	ICGC;COSMIC	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q14966	ZNF638	O14757	CHEK1	S500	R495L	495	Missense	distal	-5	no	9.280	12.257	EPSD	ICGC	5.604	Up-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q14966	ZNF638	O14757	CHEK1	S500	R506G	506	Missense	distal	6	no	9.280	9.405	EPSD	ICGC;COSMIC	5.604	Up-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q14966	ZNF638	O14757	CHEK1	S501	R495H	495	Missense	distal	-6	no	9.081	9.190	EPSD	ICGC;COSMIC	5.604	Up-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q14966	ZNF638	O14757	CHEK1	S501	R495L	495	Missense	distal	-6	no	9.081	9.185	EPSD	ICGC	5.604	Up-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q14966	ZNF638	O14757	CHEK1	S501	R506G	506	Missense	distal	5	no	9.081	8.993	EPSD	ICGC;COSMIC	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q14966	ZNF638	O14757	CHEK1	S510	M512I	512	Missense	proximal	2	no	9.474	8.894	EPSD	ICGC;COSMIC;CCLE	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q14966	ZNF638	O14757	CHEK1	S510	R506G	506	Missense	distal	-4	no	9.474	9.500	EPSD	ICGC;COSMIC	5.604	Up-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q14966	ZNF638	O14757	CHEK1	S522	R528L	528	Missense	distal	6	no	7.756	8.077	EPSD	ICGC	5.604	Up-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q14966	ZNF638	O14757	CHEK1	S522	F529C	529	Missense	distal	7	no	7.756	7.873	EPSD	ICGC;COSMIC	5.604	Up-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q14966	ZNF638	O14757	CHEK1	S537	S541L	541	Missense	distal	4	no	7.789	7.826	EPSD	ICGC	5.604	Up-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q14966	ZNF638	O14757	CHEK1	S537	R544P	544	Missense	distal	7	no	7.789	7.752	EPSD	ICGC	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q14966	ZNF638	O14757	CHEK1	S537	R544L	544	Missense	distal	7	no	7.789	7.689	EPSD	ICGC	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q14966	ZNF638	O14757	CHEK1	S537	Y533C	533	Missense	distal	-4	no	7.789	7.901	EPSD	ICGC	5.604	Up-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q14966	ZNF638	O14757	CHEK1	S539	S541L	541	Missense	proximal	2	no	9.882	9.488	EPSD	ICGC	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q14966	ZNF638	O14757	CHEK1	S539	R544P	544	Missense	distal	5	no	9.882	9.903	EPSD	ICGC	5.604	Up-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q14966	ZNF638	O14757	CHEK1	S539	R546I	546	Missense	distal	7	no	9.882	9.497	EPSD	ICGC	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q14966	ZNF638	O14757	CHEK1	S539	R544L	544	Missense	distal	5	no	9.882	9.742	EPSD	ICGC	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q14966	ZNF638	O14757	CHEK1	S539	Y533C	533	Missense	distal	-6	no	9.882	9.756	EPSD	ICGC	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q14966	ZNF638	O14757	CHEK1	S541	S541L	541	Missense	central	0	yes	7.529	0.000	EPSD	ICGC	5.604	Loss
CAMK_CAMKL_CHK1_CHEK1_ST	Q14966	ZNF638	O14757	CHEK1	S541	R544P	544	Missense	distal	3	no	7.529	7.861	EPSD	ICGC	5.604	Up-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q14966	ZNF638	O14757	CHEK1	S541	R546I	546	Missense	distal	5	no	7.529	7.489	EPSD	ICGC	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q14966	ZNF638	O14757	CHEK1	S541	R544L	544	Missense	distal	3	no	7.529	7.098	EPSD	ICGC	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q14966	ZNF638	O14757	CHEK1	S560	M564I	564	Missense	distal	4	no	8.999	8.940	EPSD	ICGC	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q14966	ZNF638	O14757	CHEK1	S560	P553Q	553	Missense	distal	-7	no	8.999	9.667	EPSD	ICGC;COSMIC	5.604	Up-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q14966	ZNF638	O14757	CHEK1	S624	N631Y	631	Missense	distal	7	no	5.919	5.175	EPSD	ICGC;COSMIC	5.604	Loss
CAMK_CAMKL_CHK1_CHEK1_ST	Q14966	ZNF638	O14757	CHEK1	S624	S628R	628	Missense	distal	4	no	5.919	5.970	EPSD	ICGC	5.604	Up-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q14966	ZNF638	O14757	CHEK1	S624	K627E	627	Missense	distal	3	no	5.919	6.735	EPSD	ICGC	5.604	Up-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q14966	ZNF638	O14757	CHEK1	S641	E645G	645	Missense	distal	4	no	6.761	6.870	EPSD	ICGC;COSMIC	5.604	Up-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q14966	ZNF638	O14757	CHEK1	S671	L672S	672	Missense	proximal	1	no	6.735	6.743	EPSD	ICGC	5.604	Up-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q14966	ZNF638	O14757	CHEK1	S743	K742N	742	Missense	proximal	-1	no	5.446	5.651	EPSD	ICGC;COSMIC	5.604	Gain
CAMK_CAMKL_CHK1_CHEK1_ST	Q14966	ZNF638	O14757	CHEK1	S801	A798S	798	Missense	distal	-3	no	6.110	3.125	EPSD	ICGC	5.604	Loss
CAMK_CAMKL_CHK1_CHEK1_ST	Q14966	ZNF638	O14757	CHEK1	S1245	D1249Y	1249	Missense	distal	4	no	6.669	6.793	EPSD	ICGC;COSMIC	5.604	Up-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q14966	ZNF638	O14757	CHEK1	S1444	R1446M	1446	Missense	proximal	2	no	6.606	6.775	EPSD	ICGC;COSMIC	5.604	Up-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q14966	ZNF638	O14757	CHEK1	S1479	G1476S	1476	Missense	distal	-3	no	6.658	4.736	EPSD	ICGC	5.604	Loss
CAMK_CAMKL_CHK1_CHEK1_ST	Q14966	ZNF638	O14757	CHEK1	T1487	Q1491K	1491	Missense	distal	4	no	9.382	9.284	EPSD	ICGC;COSMIC	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q14966	ZNF638	O14757	CHEK1	T1848	M1842L	1842	Missense	distal	-6	no	8.423	8.386	EPSD	ICGC;COSMIC	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q14966	ZNF638	O14757	CHEK1	T1848	R1845S	1845	Missense	distal	-3	no	8.423	-1.273	EPSD	ICGC	5.604	Loss
CAMK_CAMKL_CHK1_CHEK1_ST	Q14966	ZNF638	O14757	CHEK1	T1853	I1858V	1858	Missense	distal	5	no	5.828	5.886	EPSD	ICGC;COSMIC	5.604	Up-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q99590	SCAF11	O14757	CHEK1	T331	R328G	328	Missense	distal	-3	no	8.052	0.277	EPSD	ICGC	5.604	Loss
CAMK_CAMKL_CHK1_CHEK1_ST	Q99590	SCAF11	O14757	CHEK1	T331	T327K	327	Missense	distal	-4	no	8.052	8.512	EPSD	ICGC	5.604	Up-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q99590	SCAF11	O14757	CHEK1	T640	H637N	637	Missense	distal	-3	no	7.041	2.482	EPSD	ICGC	5.604	Loss
CAMK_CAMKL_CHK1_CHEK1_ST	Q99590	SCAF11	O14757	CHEK1	T640	T640N	640	Missense	central	0	yes	7.041	0.000	EPSD	ICGC	5.604	Loss
CAMK_CAMKL_CHK1_CHEK1_ST	Q99590	SCAF11	O14757	CHEK1	S731	Q728K	728	Missense	distal	-3	no	2.348	5.729	EPSD	ICGC	5.604	Gain
CAMK_CAMKL_CHK1_CHEK1_ST	Q99590	SCAF11	O14757	CHEK1	S796	R791S	791	Missense	distal	-5	no	7.134	6.923	EPSD	ICGC	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q99590	SCAF11	O14757	CHEK1	S796	S798F	798	Missense	proximal	2	no	7.134	6.990	EPSD	ICGC	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q99590	SCAF11	O14757	CHEK1	S816	Q809K	809	Missense	distal	-7	no	9.655	10.577	EPSD	ICGC	5.604	Up-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q99590	SCAF11	O14757	CHEK1	S816	P814H	814	Missense	proximal	-2	no	9.655	9.535	EPSD	ICGC;COSMIC	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q99590	SCAF11	O14757	CHEK1	T823	K829E	829	Missense	distal	6	no	9.084	8.815	EPSD	ICGC;COSMIC	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q99590	SCAF11	O14757	CHEK1	S834	N837D	837	Missense	distal	3	no	5.191	5.907	EPSD	ICGC;COSMIC	5.604	Gain
CAMK_CAMKL_CHK1_CHEK1_ST	Q99590	SCAF11	O14757	CHEK1	S846	S846F	846	Missense	central	0	yes	7.652	0.000	EPSD	ICGC	5.604	Loss
CAMK_CAMKL_CHK1_CHEK1_ST	Q99590	SCAF11	O14757	CHEK1	S850	S846F	846	Missense	distal	-4	no	9.731	9.489	EPSD	ICGC	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q99590	SCAF11	O14757	CHEK1	S902	S902Y	902	Missense	central	0	yes	7.337	0.000	EPSD	ICGC	5.604	Loss
CAMK_CAMKL_CHK1_CHEK1_ST	Q99590	SCAF11	O14757	CHEK1	S902	S902F	902	Missense	central	0	yes	7.337	0.000	EPSD	ICGC;COSMIC	5.604	Loss
CAMK_CAMKL_CHK1_CHEK1_ST	Q99590	SCAF11	O14757	CHEK1	S902	D900E	900	Missense	proximal	-2	no	7.337	7.351	EPSD	ICGC;COSMIC	5.604	Up-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q99590	SCAF11	O14757	CHEK1	S911	E913K	913	Missense	proximal	2	no	10.838	10.880	EPSD	ICGC	5.604	Up-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q99590	SCAF11	O14757	CHEK1	S937	S937Y	937	Missense	central	0	yes	8.093	0.000	EPSD	ICGC;COSMIC	5.604	Loss
CAMK_CAMKL_CHK1_CHEK1_ST	Q99590	SCAF11	O14757	CHEK1	S937	P942S	942	Missense	distal	5	no	8.093	8.175	EPSD	ICGC;COSMIC	5.604	Up-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q99590	SCAF11	O14757	CHEK1	S939	S937Y	937	Missense	proximal	-2	no	7.553	7.665	EPSD	ICGC;COSMIC	5.604	Up-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q99590	SCAF11	O14757	CHEK1	S939	P942S	942	Missense	distal	3	no	7.553	7.223	EPSD	ICGC;COSMIC	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q99590	SCAF11	O14757	CHEK1	S943	S937Y	937	Missense	distal	-6	no	6.778	6.940	EPSD	ICGC;COSMIC	5.604	Up-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q99590	SCAF11	O14757	CHEK1	S943	P942S	942	Missense	proximal	-1	no	6.778	6.331	EPSD	ICGC;COSMIC	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q99590	SCAF11	O14757	CHEK1	S953	R959S	959	Missense	distal	6	no	8.300	8.212	EPSD	ICGC;COSMIC	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q99590	SCAF11	O14757	CHEK1	S1030	K1027N	1027	Missense	distal	-3	no	8.788	2.245	EPSD	ICGC	5.604	Loss
CAMK_CAMKL_CHK1_CHEK1_ST	Q99590	SCAF11	O14757	CHEK1	S1104	S1104L	1104	Missense	central	0	yes	6.104	0.000	EPSD	ICGC;COSMIC	5.604	Loss
CAMK_CAMKL_CHK1_CHEK1_ST	Q99590	SCAF11	O14757	CHEK1	S1104	N1108K	1108	Missense	distal	4	no	6.104	6.037	EPSD	ICGC;COSMIC	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q99590	SCAF11	O14757	CHEK1	S1104	G1105E	1105	Missense	proximal	1	no	6.104	6.187	EPSD	ICGC;COSMIC	5.604	Up-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q99590	SCAF11	O14757	CHEK1	S1127	S1122Y	1122	Missense	distal	-5	no	7.093	6.409	PhosphoSitePlus	ICGC	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q99590	SCAF11	O14757	CHEK1	S1170	P1172T	1172	Missense	proximal	2	no	8.243	7.927	EPSD	ICGC	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q99590	SCAF11	O14757	CHEK1	S1170	Q1173K	1173	Missense	distal	3	no	8.243	7.827	EPSD	ICGC;COSMIC	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q99590	SCAF11	O14757	CHEK1	S1170	S1169Y	1169	Missense	proximal	-1	no	8.243	8.571	EPSD	ICGC	5.604	Up-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q99590	SCAF11	O14757	CHEK1	S1189	N1195K	1195	Missense	distal	6	no	7.193	7.058	EPSD	ICGC	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q99590	SCAF11	O14757	CHEK1	S1189	Q1186K	1186	Missense	distal	-3	no	7.193	10.574	EPSD	ICGC;COSMIC	5.604	Up-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q9UQ35	SRRM2	O14757	CHEK1	S24	V19I	19	Missense	distal	-5	no	11.692	13.137	EPSD	ICGC;COSMIC	5.604	Up-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q9UQ35	SRRM2	O14757	CHEK1	T111	V118F	118	Missense	distal	7	no	6.570	6.011	EPSD	ICGC	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q9UQ35	SRRM2	O14757	CHEK1	T111	G107S	107	Missense	distal	-4	no	6.570	6.236	EPSD	ICGC;COSMIC	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q9UQ35	SRRM2	O14757	CHEK1	S202	E208D	208	Missense	distal	6	no	6.308	6.395	EPSD	ICGC;COSMIC	5.604	Up-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q9UQ35	SRRM2	O14757	CHEK1	S212	K217Q	217	Missense	distal	5	no	6.451	6.403	EPSD	ICGC	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q9UQ35	SRRM2	O14757	CHEK1	S212	E208D	208	Missense	distal	-4	no	6.451	6.310	EPSD	ICGC;COSMIC	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q9UQ35	SRRM2	O14757	CHEK1	S220	R227H	227	Missense	distal	7	no	8.015	7.722	EPSD	ICGC;COSMIC	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q9UQ35	SRRM2	O14757	CHEK1	S220	K217Q	217	Missense	distal	-3	no	8.015	4.634	EPSD	ICGC	5.604	Loss
CAMK_CAMKL_CHK1_CHEK1_ST	Q9UQ35	SRRM2	O14757	CHEK1	S220	R227L	227	Missense	distal	7	no	8.015	7.915	EPSD	ICGC;COSMIC	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q9UQ35	SRRM2	O14757	CHEK1	S222	R227H	227	Missense	distal	5	no	11.709	11.725	EPSD	ICGC;COSMIC	5.604	Up-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q9UQ35	SRRM2	O14757	CHEK1	S222	K217Q	217	Missense	distal	-5	no	11.709	10.138	EPSD	ICGC	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q9UQ35	SRRM2	O14757	CHEK1	S222	R227L	227	Missense	distal	5	no	11.709	11.569	EPSD	ICGC;COSMIC	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q9UQ35	SRRM2	O14757	CHEK1	T233	R227H	227	Missense	distal	-6	no	8.336	8.446	EPSD	ICGC;COSMIC	5.604	Up-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q9UQ35	SRRM2	O14757	CHEK1	T233	R230M	230	Missense	distal	-3	no	8.336	3.187	EPSD	ICGC;GDSC	5.604	Loss
CAMK_CAMKL_CHK1_CHEK1_ST	Q9UQ35	SRRM2	O14757	CHEK1	T233	R227L	227	Missense	distal	-6	no	8.336	8.440	EPSD	ICGC;COSMIC	5.604	Up-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q9UQ35	SRRM2	O14757	CHEK1	S248	R247W	247	Missense	proximal	-1	no	10.348	10.465	EPSD	ICGC;COSMIC	5.604	Up-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q9UQ35	SRRM2	O14757	CHEK1	S248	T251K	251	Missense	distal	3	no	10.348	11.135	EPSD	ICGC;COSMIC	5.604	Up-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q9UQ35	SRRM2	O14757	CHEK1	S250	R247W	247	Missense	distal	-3	no	7.002	-26.602	EPSD	ICGC;COSMIC	5.604	Loss
CAMK_CAMKL_CHK1_CHEK1_ST	Q9UQ35	SRRM2	O14757	CHEK1	S250	T251K	251	Missense	proximal	1	no	7.002	7.020	EPSD	ICGC;COSMIC	5.604	Up-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q9UQ35	SRRM2	O14757	CHEK1	T252	R247W	247	Missense	distal	-5	no	7.267	6.408	EPSD	ICGC;COSMIC	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q9UQ35	SRRM2	O14757	CHEK1	T252	T251K	251	Missense	proximal	-1	no	7.267	7.076	EPSD	ICGC;COSMIC	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q9UQ35	SRRM2	O14757	CHEK1	S279	R278L	278	Missense	proximal	-1	no	10.720	10.820	EPSD	ICGC	5.604	Up-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q9UQ35	SRRM2	O14757	CHEK1	S281	R278L	278	Missense	distal	-3	no	8.075	-10.472	EPSD	ICGC	5.604	Loss
CAMK_CAMKL_CHK1_CHEK1_ST	Q9UQ35	SRRM2	O14757	CHEK1	S297	P298T	298	Missense	proximal	1	no	8.855	8.899	EPSD	ICGC;COSMIC	5.604	Up-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q9UQ35	SRRM2	O14757	CHEK1	S297	R303L	303	Missense	distal	6	no	8.855	9.176	EPSD	ICGC	5.604	Up-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q9UQ35	SRRM2	O14757	CHEK1	S323	P324Q	324	Missense	proximal	1	no	9.116	9.187	EPSD	ICGC;COSMIC	5.604	Up-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q9UQ35	SRRM2	O14757	CHEK1	T348	P354L	354	Missense	distal	6	no	5.816	5.606	EPSD	ICGC;COSMIC	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q9UQ35	SRRM2	O14757	CHEK1	T359	P354L	354	Missense	distal	-5	no	3.995	8.702	EPSD	ICGC;COSMIC	5.604	Gain
CAMK_CAMKL_CHK1_CHEK1_ST	Q9UQ35	SRRM2	O14757	CHEK1	S404	R401Q	401	Missense	distal	-3	no	9.541	2.334	EPSD	ICGC;COSMIC	5.604	Loss
CAMK_CAMKL_CHK1_CHEK1_ST	Q9UQ35	SRRM2	O14757	CHEK1	S404	P399S	399	Missense	distal	-5	no	9.541	11.060	EPSD	ICGC	5.604	Up-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q9UQ35	SRRM2	O14757	CHEK1	S486	A488S	488	Missense	proximal	2	no	6.013	5.557	EPSD	ICGC;COSMIC	5.604	Loss
CAMK_CAMKL_CHK1_CHEK1_ST	Q9UQ35	SRRM2	O14757	CHEK1	S486	G493W	493	Missense	distal	7	no	6.013	5.505	EPSD	ICGC;COSMIC	5.604	Loss
CAMK_CAMKL_CHK1_CHEK1_ST	Q9UQ35	SRRM2	O14757	CHEK1	S495	A488S	488	Missense	distal	-7	no	6.706	6.256	EPSD	ICGC;COSMIC	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q9UQ35	SRRM2	O14757	CHEK1	S495	R496L	496	Missense	proximal	1	no	6.706	6.671	EPSD	ICGC;COSMIC	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q9UQ35	SRRM2	O14757	CHEK1	S495	G493W	493	Missense	proximal	-2	no	6.706	6.794	EPSD	ICGC;COSMIC	5.604	Up-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q9UQ35	SRRM2	O14757	CHEK1	S497	R496L	496	Missense	proximal	-1	no	11.538	11.637	EPSD	ICGC;COSMIC	5.604	Up-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q9UQ35	SRRM2	O14757	CHEK1	S497	G493W	493	Missense	distal	-4	no	11.538	10.750	EPSD	ICGC;COSMIC	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q9UQ35	SRRM2	O14757	CHEK1	T499	R496L	496	Missense	distal	-3	no	8.894	-9.653	EPSD	ICGC;COSMIC	5.604	Loss
CAMK_CAMKL_CHK1_CHEK1_ST	Q9UQ35	SRRM2	O14757	CHEK1	T499	G493W	493	Missense	distal	-6	no	8.894	9.096	EPSD	ICGC;COSMIC	5.604	Up-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q9UQ35	SRRM2	O14757	CHEK1	T501	R496L	496	Missense	distal	-5	no	10.444	13.421	EPSD	ICGC;COSMIC	5.604	Up-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q9UQ35	SRRM2	O14757	CHEK1	S518	G523R	523	Missense	distal	5	no	9.935	10.023	EPSD	ICGC	5.604	Up-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q9UQ35	SRRM2	O14757	CHEK1	S527	G523R	523	Missense	distal	-4	no	10.142	10.116	EPSD	ICGC	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q9UQ35	SRRM2	O14757	CHEK1	S527	R533C	533	Missense	distal	6	no	10.142	10.436	EPSD	ICGC;COSMIC	5.604	Up-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q9UQ35	SRRM2	O14757	CHEK1	S534	R533C	533	Missense	proximal	-1	no	10.389	10.424	EPSD	ICGC;COSMIC	5.604	Up-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q9UQ35	SRRM2	O14757	CHEK1	S534	P537F	537	Missense	distal	3	no	10.389	10.248	EPSD	ICGC	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q9UQ35	SRRM2	O14757	CHEK1	S534	R535S	535	Missense	proximal	1	no	10.389	10.363	EPSD	ICGC;COSMIC	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q9UQ35	SRRM2	O14757	CHEK1	S536	S543C	543	Missense	distal	7	no	10.394	10.081	EPSD	ICGC;COSMIC	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q9UQ35	SRRM2	O14757	CHEK1	S536	W542L	542	Missense	distal	6	no	10.394	10.250	EPSD	ICGC	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q9UQ35	SRRM2	O14757	CHEK1	S536	R533C	533	Missense	distal	-3	no	10.394	2.303	EPSD	ICGC;COSMIC	5.604	Loss
CAMK_CAMKL_CHK1_CHEK1_ST	Q9UQ35	SRRM2	O14757	CHEK1	S536	P537F	537	Missense	proximal	1	no	10.394	10.426	EPSD	ICGC	5.604	Up-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q9UQ35	SRRM2	O14757	CHEK1	S536	R535S	535	Missense	proximal	-1	no	10.394	10.233	EPSD	ICGC;COSMIC	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q9UQ35	SRRM2	O14757	CHEK1	S543	S543C	543	Missense	central	0	yes	5.717	0.000	EPSD	ICGC;COSMIC	5.604	Loss
CAMK_CAMKL_CHK1_CHEK1_ST	Q9UQ35	SRRM2	O14757	CHEK1	S543	W542L	542	Missense	proximal	-1	no	5.717	5.700	EPSD	ICGC	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q9UQ35	SRRM2	O14757	CHEK1	S543	P537F	537	Missense	distal	-6	no	5.717	5.894	EPSD	ICGC	5.604	Up-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q9UQ35	SRRM2	O14757	CHEK1	S562	S564F	564	Missense	proximal	2	no	7.793	7.649	EPSD	ICGC	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q9UQ35	SRRM2	O14757	CHEK1	S562	S566P	566	Missense	distal	4	no	7.793	7.933	EPSD	ICGC;COSMIC	5.604	Up-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q9UQ35	SRRM2	O14757	CHEK1	S564	G571V	571	Missense	distal	7	no	10.230	10.260	EPSD	ICGC	5.604	Up-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q9UQ35	SRRM2	O14757	CHEK1	S564	S564F	564	Missense	central	0	yes	10.230	0.000	EPSD	ICGC	5.604	Loss
CAMK_CAMKL_CHK1_CHEK1_ST	Q9UQ35	SRRM2	O14757	CHEK1	S564	S566P	566	Missense	proximal	2	no	10.230	10.154	EPSD	ICGC;COSMIC	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q9UQ35	SRRM2	O14757	CHEK1	S573	G571V	571	Missense	proximal	-2	no	7.570	7.629	EPSD	ICGC	5.604	Up-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q9UQ35	SRRM2	O14757	CHEK1	S573	R574L	574	Missense	proximal	1	no	7.570	7.536	EPSD	ICGC	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q9UQ35	SRRM2	O14757	CHEK1	S573	S566P	566	Missense	distal	-7	no	7.570	6.901	EPSD	ICGC;COSMIC	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q9UQ35	SRRM2	O14757	CHEK1	S575	G571V	571	Missense	distal	-4	no	11.312	11.278	EPSD	ICGC	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q9UQ35	SRRM2	O14757	CHEK1	S575	R574L	574	Missense	proximal	-1	no	11.312	11.411	EPSD	ICGC	5.604	Up-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q9UQ35	SRRM2	O14757	CHEK1	T577	S584F	584	Missense	distal	7	no	10.330	9.900	EPSD	ICGC;COSMIC	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q9UQ35	SRRM2	O14757	CHEK1	T577	G571V	571	Missense	distal	-6	no	10.330	10.304	EPSD	ICGC	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q9UQ35	SRRM2	O14757	CHEK1	T577	R574L	574	Missense	distal	-3	no	10.330	-8.217	EPSD	ICGC	5.604	Loss
CAMK_CAMKL_CHK1_CHEK1_ST	Q9UQ35	SRRM2	O14757	CHEK1	S584	S584F	584	Missense	central	0	yes	7.028	0.000	EPSD	ICGC;COSMIC	5.604	Loss
CAMK_CAMKL_CHK1_CHEK1_ST	Q9UQ35	SRRM2	O14757	CHEK1	S584	R585C	585	Missense	proximal	1	no	7.028	7.018	EPSD	ICGC;COSMIC	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q9UQ35	SRRM2	O14757	CHEK1	S586	S584F	584	Missense	proximal	-2	no	9.434	9.723	EPSD	ICGC;COSMIC	5.604	Up-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q9UQ35	SRRM2	O14757	CHEK1	S586	R585C	585	Missense	proximal	-1	no	9.434	9.469	EPSD	ICGC;COSMIC	5.604	Up-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q9UQ35	SRRM2	O14757	CHEK1	S586	R593I	593	Missense	distal	7	no	9.434	9.049	EPSD	ICGC	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q9UQ35	SRRM2	O14757	CHEK1	T588	S584F	584	Missense	distal	-4	no	9.565	9.323	EPSD	ICGC;COSMIC	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q9UQ35	SRRM2	O14757	CHEK1	T588	R585C	585	Missense	distal	-3	no	9.565	1.474	EPSD	ICGC;COSMIC	5.604	Loss
CAMK_CAMKL_CHK1_CHEK1_ST	Q9UQ35	SRRM2	O14757	CHEK1	T588	R593I	593	Missense	distal	5	no	9.565	9.525	EPSD	ICGC	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q9UQ35	SRRM2	O14757	CHEK1	S594	R593I	593	Missense	proximal	-1	no	8.725	8.681	EPSD	ICGC	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q9UQ35	SRRM2	O14757	CHEK1	S594	R601M	601	Missense	distal	7	no	8.725	8.617	EPSD	ICGC	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q9UQ35	SRRM2	O14757	CHEK1	S596	R593I	593	Missense	distal	-3	no	9.124	0.366	EPSD	ICGC	5.604	Loss
CAMK_CAMKL_CHK1_CHEK1_ST	Q9UQ35	SRRM2	O14757	CHEK1	S596	R601M	601	Missense	distal	5	no	9.124	9.115	EPSD	ICGC	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q9UQ35	SRRM2	O14757	CHEK1	T598	R593I	593	Missense	distal	-5	no	9.349	10.295	EPSD	ICGC	5.604	Up-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q9UQ35	SRRM2	O14757	CHEK1	T598	R601M	601	Missense	distal	3	no	9.349	9.265	EPSD	ICGC	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q9UQ35	SRRM2	O14757	CHEK1	T600	R593I	593	Missense	distal	-7	no	10.532	10.149	EPSD	ICGC	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q9UQ35	SRRM2	O14757	CHEK1	T600	R601M	601	Missense	proximal	1	no	10.532	10.493	EPSD	ICGC	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q9UQ35	SRRM2	O14757	CHEK1	S604	R601M	601	Missense	distal	-3	no	9.233	4.084	EPSD	ICGC	5.604	Loss
CAMK_CAMKL_CHK1_CHEK1_ST	Q9UQ35	SRRM2	O14757	CHEK1	S606	R601M	601	Missense	distal	-5	no	11.265	9.868	EPSD	ICGC	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q9UQ35	SRRM2	O14757	CHEK1	T608	R601M	601	Missense	distal	-7	no	8.834	8.693	EPSD	ICGC	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q9UQ35	SRRM2	O14757	CHEK1	T608	R614S	614	Missense	distal	6	no	8.834	8.746	EPSD	ICGC	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q9UQ35	SRRM2	O14757	CHEK1	S615	A621P	621	Missense	distal	6	no	8.413	8.644	EPSD	ICGC;COSMIC	5.604	Up-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q9UQ35	SRRM2	O14757	CHEK1	S615	R614S	614	Missense	proximal	-1	no	8.413	8.252	EPSD	ICGC	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q9UQ35	SRRM2	O14757	CHEK1	S617	A621P	621	Missense	distal	4	no	10.600	10.547	EPSD	ICGC;COSMIC	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q9UQ35	SRRM2	O14757	CHEK1	S617	R623L	623	Missense	distal	6	no	10.600	10.922	EPSD	ICGC;COSMIC	5.604	Up-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q9UQ35	SRRM2	O14757	CHEK1	S617	R614S	614	Missense	distal	-3	no	10.600	0.904	EPSD	ICGC	5.604	Loss
CAMK_CAMKL_CHK1_CHEK1_ST	Q9UQ35	SRRM2	O14757	CHEK1	T619	A621P	621	Missense	proximal	2	no	9.168	8.635	EPSD	ICGC;COSMIC	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q9UQ35	SRRM2	O14757	CHEK1	T619	R623L	623	Missense	distal	4	no	9.168	9.154	EPSD	ICGC;COSMIC	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q9UQ35	SRRM2	O14757	CHEK1	T619	R614S	614	Missense	distal	-5	no	9.168	8.957	EPSD	ICGC	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q9UQ35	SRRM2	O14757	CHEK1	S625	A621P	621	Missense	distal	-4	no	10.749	10.606	EPSD	ICGC;COSMIC	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q9UQ35	SRRM2	O14757	CHEK1	S625	R623L	623	Missense	proximal	-2	no	10.749	10.755	EPSD	ICGC;COSMIC	5.604	Up-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q9UQ35	SRRM2	O14757	CHEK1	T627	A621P	621	Missense	distal	-6	no	8.793	9.017	EPSD	ICGC;COSMIC	5.604	Up-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q9UQ35	SRRM2	O14757	CHEK1	T627	R633C	633	Missense	distal	6	no	8.793	9.087	EPSD	ICGC;COSMIC	5.604	Up-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q9UQ35	SRRM2	O14757	CHEK1	T627	R623L	623	Missense	distal	-4	no	8.793	8.537	EPSD	ICGC;COSMIC	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q9UQ35	SRRM2	O14757	CHEK1	S629	R633C	633	Missense	distal	4	no	9.936	10.040	EPSD	ICGC;COSMIC	5.604	Up-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q9UQ35	SRRM2	O14757	CHEK1	S629	R623L	623	Missense	distal	-6	no	9.936	10.040	EPSD	ICGC;COSMIC	5.604	Up-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q9UQ35	SRRM2	O14757	CHEK1	S635	R633C	633	Missense	proximal	-2	no	9.654	9.602	EPSD	ICGC;COSMIC	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q9UQ35	SRRM2	O14757	CHEK1	S635	S639L	639	Missense	distal	4	no	9.654	9.690	EPSD	ICGC;COSMIC	5.604	Up-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q9UQ35	SRRM2	O14757	CHEK1	S637	R633C	633	Missense	distal	-4	no	11.078	10.704	EPSD	ICGC;COSMIC	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q9UQ35	SRRM2	O14757	CHEK1	S637	S639L	639	Missense	proximal	2	no	11.078	10.684	EPSD	ICGC;COSMIC	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q9UQ35	SRRM2	O14757	CHEK1	S639	R633C	633	Missense	distal	-6	no	10.214	10.330	EPSD	ICGC;COSMIC	5.604	Up-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q9UQ35	SRRM2	O14757	CHEK1	S639	S639L	639	Missense	central	0	yes	10.214	0.000	EPSD	ICGC;COSMIC	5.604	Loss
CAMK_CAMKL_CHK1_CHEK1_ST	Q9UQ35	SRRM2	O14757	CHEK1	S644	S649Y	649	Missense	distal	5	no	6.073	5.619	EPSD	ICGC	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q9UQ35	SRRM2	O14757	CHEK1	S644	S639L	639	Missense	distal	-5	no	6.073	9.261	EPSD	ICGC;COSMIC	5.604	Up-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q9UQ35	SRRM2	O14757	CHEK1	S649	S649Y	649	Missense	central	0	yes	8.534	0.000	EPSD	ICGC	5.604	Loss
CAMK_CAMKL_CHK1_CHEK1_ST	Q9UQ35	SRRM2	O14757	CHEK1	T651	S649Y	649	Missense	proximal	-2	no	9.375	9.487	EPSD	ICGC	5.604	Up-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q9UQ35	SRRM2	O14757	CHEK1	S660	G667C	667	Missense	distal	7	no	11.050	10.638	EPSD	ICGC;COSMIC	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q9UQ35	SRRM2	O14757	CHEK1	T662	G667C	667	Missense	distal	5	no	8.408	8.252	EPSD	ICGC;COSMIC	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q9UQ35	SRRM2	O14757	CHEK1	T662	S669A	669	Missense	distal	7	no	8.408	8.458	EPSD	ICGC;COSMIC	5.604	Up-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q9UQ35	SRRM2	O14757	CHEK1	S669	A675G	675	Missense	distal	6	no	8.147	7.971	EPSD	ICGC;COSMIC	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q9UQ35	SRRM2	O14757	CHEK1	S669	G667C	667	Missense	proximal	-2	no	8.147	8.062	EPSD	ICGC;COSMIC	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q9UQ35	SRRM2	O14757	CHEK1	S669	S669A	669	Missense	central	0	yes	8.147	0.000	EPSD	ICGC;COSMIC	5.604	Loss
CAMK_CAMKL_CHK1_CHEK1_ST	Q9UQ35	SRRM2	O14757	CHEK1	S669	T673P	673	Missense	distal	4	no	8.147	8.276	EPSD	ICGC;COSMIC	5.604	Up-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q9UQ35	SRRM2	O14757	CHEK1	S671	A675G	675	Missense	distal	4	no	10.095	9.968	EPSD	ICGC;COSMIC	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q9UQ35	SRRM2	O14757	CHEK1	S671	G667C	667	Missense	distal	-4	no	10.095	9.695	EPSD	ICGC;COSMIC	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q9UQ35	SRRM2	O14757	CHEK1	S671	S669A	669	Missense	proximal	-2	no	10.095	10.210	EPSD	ICGC;COSMIC	5.604	Up-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q9UQ35	SRRM2	O14757	CHEK1	S671	T673P	673	Missense	proximal	2	no	10.095	10.410	EPSD	ICGC;COSMIC	5.604	Up-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q9UQ35	SRRM2	O14757	CHEK1	T673	A675G	675	Missense	proximal	2	no	9.960	9.439	EPSD	ICGC;COSMIC	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q9UQ35	SRRM2	O14757	CHEK1	T673	G667C	667	Missense	distal	-6	no	9.960	9.958	EPSD	ICGC;COSMIC	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q9UQ35	SRRM2	O14757	CHEK1	T673	S669A	669	Missense	distal	-4	no	9.960	10.339	EPSD	ICGC;COSMIC	5.604	Up-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q9UQ35	SRRM2	O14757	CHEK1	T673	T673P	673	Missense	central	0	yes	9.960	0.000	EPSD	ICGC;COSMIC	5.604	Loss
CAMK_CAMKL_CHK1_CHEK1_ST	Q9UQ35	SRRM2	O14757	CHEK1	S683	R684T	684	Missense	proximal	1	no	9.973	9.955	EPSD	ICGC;COSMIC	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q9UQ35	SRRM2	O14757	CHEK1	S683	R682C	682	Missense	proximal	-1	no	9.973	10.008	EPSD	ICGC;COSMIC	5.604	Up-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q9UQ35	SRRM2	O14757	CHEK1	T685	R684T	684	Missense	proximal	-1	no	9.371	9.414	EPSD	ICGC;COSMIC	5.604	Up-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q9UQ35	SRRM2	O14757	CHEK1	T685	R682C	682	Missense	distal	-3	no	9.371	1.279	EPSD	ICGC;COSMIC	5.604	Loss
CAMK_CAMKL_CHK1_CHEK1_ST	Q9UQ35	SRRM2	O14757	CHEK1	S692	S694C	694	Missense	proximal	2	no	5.825	5.464	EPSD	ICGC;COSMIC	5.604	Loss
CAMK_CAMKL_CHK1_CHEK1_ST	Q9UQ35	SRRM2	O14757	CHEK1	S694	S694C	694	Missense	central	0	yes	11.190	0.000	EPSD	ICGC;COSMIC	5.604	Loss
CAMK_CAMKL_CHK1_CHEK1_ST	Q9UQ35	SRRM2	O14757	CHEK1	T696	S694C	694	Missense	proximal	-2	no	8.455	8.502	EPSD	ICGC;COSMIC	5.604	Up-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q9UQ35	SRRM2	O14757	CHEK1	S724	S728L	728	Missense	distal	4	no	9.792	9.828	EPSD	ICGC	5.604	Up-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q9UQ35	SRRM2	O14757	CHEK1	S726	S728L	728	Missense	proximal	2	no	9.372	8.978	EPSD	ICGC	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q9UQ35	SRRM2	O14757	CHEK1	T736	S734F	734	Missense	proximal	-2	no	6.428	6.718	EPSD	ICGC	5.604	Up-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q9UQ35	SRRM2	O14757	CHEK1	S761	R766L	766	Missense	distal	5	no	7.275	7.134	EPSD	ICGC;COSMIC	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q9UQ35	SRRM2	O14757	CHEK1	S763	R766L	766	Missense	distal	3	no	9.043	8.611	EPSD	ICGC;COSMIC	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q9UQ35	SRRM2	O14757	CHEK1	S771	R766L	766	Missense	distal	-5	no	4.368	7.345	EPSD	ICGC;COSMIC	5.604	Gain
CAMK_CAMKL_CHK1_CHEK1_ST	Q9UQ35	SRRM2	O14757	CHEK1	S780	C785F	785	Missense	distal	5	no	11.388	11.410	EPSD	ICGC;GDSC;CCLE	5.604	Up-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q9UQ35	SRRM2	O14757	CHEK1	S799	P804T	804	Missense	distal	5	no	5.671	5.531	EPSD	ICGC;COSMIC	5.604	Loss
CAMK_CAMKL_CHK1_CHEK1_ST	Q9UQ35	SRRM2	O14757	CHEK1	S799	S797G	797	Missense	proximal	-2	no	5.671	5.804	EPSD	ICGC;COSMIC	5.604	Up-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q9UQ35	SRRM2	O14757	CHEK1	S799	S801F	801	Missense	proximal	2	no	5.671	5.527	EPSD	ICGC;COSMIC	5.604	Loss
CAMK_CAMKL_CHK1_CHEK1_ST	Q9UQ35	SRRM2	O14757	CHEK1	S799	R798C	798	Missense	proximal	-1	no	5.671	5.706	EPSD	ICGC	5.604	Up-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q9UQ35	SRRM2	O14757	CHEK1	S817	S817C	817	Missense	central	0	yes	6.577	0.000	EPSD	ICGC;COSMIC;GDSC;CCLE	5.604	Loss
CAMK_CAMKL_CHK1_CHEK1_ST	Q9UQ35	SRRM2	O14757	CHEK1	S819	S817C	817	Missense	proximal	-2	no	7.934	7.982	EPSD	ICGC;COSMIC;GDSC;CCLE	5.604	Up-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q9UQ35	SRRM2	O14757	CHEK1	S831	S827Y	827	Missense	distal	-4	no	8.136	7.959	EPSD	ICGC;COSMIC	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q9UQ35	SRRM2	O14757	CHEK1	S887	R884M	884	Missense	distal	-3	no	9.297	4.148	EPSD	ICGC;COSMIC	5.604	Loss
CAMK_CAMKL_CHK1_CHEK1_ST	Q9UQ35	SRRM2	O14757	CHEK1	S901	P897L	897	Missense	distal	-4	no	6.530	6.345	EPSD	ICGC;COSMIC	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q9UQ35	SRRM2	O14757	CHEK1	S901	S908N	908	Missense	distal	7	no	6.530	6.759	EPSD	ICGC;COSMIC	5.604	Up-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q9UQ35	SRRM2	O14757	CHEK1	S929	S924P	924	Missense	distal	-5	no	8.316	6.797	EPSD	ICGC	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q9UQ35	SRRM2	O14757	CHEK1	S1101	K1095M	1095	Missense	distal	-6	no	6.646	6.798	EPSD	ICGC;COSMIC	5.604	Up-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q9UQ35	SRRM2	O14757	CHEK1	S1101	R1098W	1098	Missense	distal	-3	no	6.646	-26.957	EPSD	ICGC;COSMIC;GDSC;CCLE	5.604	Loss
CAMK_CAMKL_CHK1_CHEK1_ST	Q9UQ35	SRRM2	O14757	CHEK1	S1101	V1105F	1105	Missense	distal	4	no	6.646	6.633	EPSD	ICGC;COSMIC	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q9UQ35	SRRM2	O14757	CHEK1	S1140	P1146S	1146	Missense	distal	6	no	6.166	5.547	EPSD	ICGC;COSMIC	5.604	Loss
CAMK_CAMKL_CHK1_CHEK1_ST	Q9UQ35	SRRM2	O14757	CHEK1	S1384	R1377K	1377	Missense	distal	-7	no	5.160	6.340	EPSD	ICGC	5.604	Gain
CAMK_CAMKL_CHK1_CHEK1_ST	Q9UQ35	SRRM2	O14757	CHEK1	S1436	R1433T	1433	Missense	distal	-3	no	12.624	-7.945	EPSD	ICGC	5.604	Loss
CAMK_CAMKL_CHK1_CHEK1_ST	Q9UQ35	SRRM2	O14757	CHEK1	S1436	S1443C	1443	Missense	distal	7	no	12.624	12.311	EPSD	ICGC;COSMIC	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q9UQ35	SRRM2	O14757	CHEK1	S1441	S1443C	1443	Missense	proximal	2	no	7.836	7.474	EPSD	ICGC;COSMIC	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q9UQ35	SRRM2	O14757	CHEK1	S1443	S1443C	1443	Missense	central	0	yes	5.936	0.000	EPSD	ICGC;COSMIC	5.604	Loss
CAMK_CAMKL_CHK1_CHEK1_ST	Q9UQ35	SRRM2	O14757	CHEK1	S1443	G1450V	1450	Missense	distal	7	no	5.936	5.966	EPSD	ICGC	5.604	Up-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q9UQ35	SRRM2	O14757	CHEK1	S1451	S1455L	1455	Missense	distal	4	no	9.066	9.102	EPSD	ICGC;COSMIC	5.604	Up-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q9UQ35	SRRM2	O14757	CHEK1	S1451	G1450V	1450	Missense	proximal	-1	no	9.066	9.142	EPSD	ICGC	5.604	Up-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q9UQ35	SRRM2	O14757	CHEK1	S1474	S1474A	1474	Missense	central	0	yes	10.843	0.000	EPSD	ICGC;COSMIC	5.604	Loss
CAMK_CAMKL_CHK1_CHEK1_ST	Q9UQ35	SRRM2	O14757	CHEK1	S1474	E1479K	1479	Missense	distal	5	no	10.843	10.778	EPSD	ICGC	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q9UQ35	SRRM2	O14757	CHEK1	S1474	P1470H	1470	Missense	distal	-4	no	10.843	10.717	EPSD	ICGC;COSMIC	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q9UQ35	SRRM2	O14757	CHEK1	S1474	D1468A	1468	Missense	distal	-6	no	10.843	10.889	EPSD	ICGC;COSMIC	5.604	Up-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q9UQ35	SRRM2	O14757	CHEK1	S1478	S1474A	1474	Missense	distal	-4	no	8.662	9.041	EPSD	ICGC;COSMIC	5.604	Up-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q9UQ35	SRRM2	O14757	CHEK1	S1478	E1479K	1479	Missense	proximal	1	no	8.662	8.588	EPSD	ICGC	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q9UQ35	SRRM2	O14757	CHEK1	S1517	G1518R	1518	Missense	proximal	1	no	7.818	7.827	EPSD	ICGC;COSMIC	5.604	Up-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q9UQ35	SRRM2	O14757	CHEK1	S1517	S1517I	1517	Missense	central	0	yes	7.818	0.000	EPSD	ICGC;COSMIC	5.604	Loss
CAMK_CAMKL_CHK1_CHEK1_ST	Q9UQ35	SRRM2	O14757	CHEK1	S1519	G1518R	1518	Missense	proximal	-1	no	7.222	7.205	EPSD	ICGC;COSMIC	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q9UQ35	SRRM2	O14757	CHEK1	S1519	S1517I	1517	Missense	proximal	-2	no	7.222	7.350	EPSD	ICGC;COSMIC	5.604	Up-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q9UQ35	SRRM2	O14757	CHEK1	S1521	G1518R	1518	Missense	distal	-3	no	0.820	8.594	EPSD	ICGC;COSMIC	5.604	Gain
CAMK_CAMKL_CHK1_CHEK1_ST	Q9UQ35	SRRM2	O14757	CHEK1	S1539	R1538L	1538	Missense	proximal	-1	no	7.300	7.399	EPSD	ICGC	5.604	Up-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q9UQ35	SRRM2	O14757	CHEK1	S1541	R1538L	1538	Missense	distal	-3	no	8.184	-10.363	EPSD	ICGC	5.604	Loss
CAMK_CAMKL_CHK1_CHEK1_ST	Q9UQ35	SRRM2	O14757	CHEK1	S1577	R1570I	1570	Missense	distal	-7	no	7.120	6.737	EPSD	ICGC	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q9UQ35	SRRM2	O14757	CHEK1	S1596	S1601F	1601	Missense	distal	5	no	6.205	5.880	EPSD	ICGC	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q9UQ35	SRRM2	O14757	CHEK1	S1596	R1594L	1594	Missense	proximal	-2	no	6.205	6.211	EPSD	ICGC;COSMIC	5.604	Up-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q9UQ35	SRRM2	O14757	CHEK1	S1598	S1601F	1601	Missense	distal	3	no	6.624	6.812	EPSD	ICGC	5.604	Up-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q9UQ35	SRRM2	O14757	CHEK1	S1598	R1594L	1594	Missense	distal	-4	no	6.624	6.368	EPSD	ICGC;COSMIC	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q9UQ35	SRRM2	O14757	CHEK1	S1600	S1601F	1601	Missense	proximal	1	no	8.519	8.514	EPSD	ICGC	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q9UQ35	SRRM2	O14757	CHEK1	S1600	R1594L	1594	Missense	distal	-6	no	8.519	8.623	EPSD	ICGC;COSMIC	5.604	Up-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q9UQ35	SRRM2	O14757	CHEK1	S1616	R1613S	1613	Missense	distal	-3	no	8.302	-1.394	EPSD	ICGC;COSMIC	5.604	Loss
CAMK_CAMKL_CHK1_CHEK1_ST	Q9UQ35	SRRM2	O14757	CHEK1	S1638	R1635Q	1635	Missense	distal	-3	no	7.683	0.476	EPSD	ICGC;COSMIC;GDSC	5.604	Loss
CAMK_CAMKL_CHK1_CHEK1_ST	Q9UQ35	SRRM2	O14757	CHEK1	S1640	R1635Q	1635	Missense	distal	-5	no	7.474	7.078	EPSD	ICGC;COSMIC;GDSC	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q9UQ35	SRRM2	O14757	CHEK1	S1648	S1653I	1653	Missense	distal	5	no	12.260	12.116	EPSD	ICGC	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q9UQ35	SRRM2	O14757	CHEK1	S1648	E1650K	1650	Missense	proximal	2	no	12.260	12.302	EPSD	ICGC;COSMIC	5.604	Up-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q9UQ35	SRRM2	O14757	CHEK1	S1653	E1650K	1650	Missense	distal	-3	no	2.450	5.712	EPSD	ICGC;COSMIC	5.604	Gain
CAMK_CAMKL_CHK1_CHEK1_ST	Q9UQ35	SRRM2	O14757	CHEK1	S1672	G1671V	1671	Missense	proximal	-1	no	10.112	10.189	EPSD	ICGC;COSMIC	5.604	Up-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q9UQ35	SRRM2	O14757	CHEK1	S1672	R1669S	1669	Missense	distal	-3	no	10.112	0.416	EPSD	ICGC;COSMIC	5.604	Loss
CAMK_CAMKL_CHK1_CHEK1_ST	Q9UQ35	SRRM2	O14757	CHEK1	S1690	P1695Q	1695	Missense	distal	5	no	6.896	6.950	EPSD	ICGC;COSMIC	5.604	Up-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q9UQ35	SRRM2	O14757	CHEK1	S1690	R1689C	1689	Missense	proximal	-1	no	6.896	6.931	EPSD	ICGC;COSMIC	5.604	Up-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q9UQ35	SRRM2	O14757	CHEK1	S1691	P1695Q	1695	Missense	distal	4	no	5.807	5.717	EPSD	ICGC;COSMIC	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q9UQ35	SRRM2	O14757	CHEK1	S1691	R1689C	1689	Missense	proximal	-2	no	5.807	5.755	EPSD	ICGC;COSMIC	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q9UQ35	SRRM2	O14757	CHEK1	S1711	R1717C	1717	Missense	distal	6	no	6.961	7.255	EPSD	ICGC;COSMIC	5.604	Up-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q9UQ35	SRRM2	O14757	CHEK1	S1711	S1707R	1707	Missense	distal	-4	no	6.961	7.269	EPSD	ICGC;COSMIC	5.604	Up-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q9UQ35	SRRM2	O14757	CHEK1	S1711	R1708H	1708	Missense	distal	-3	no	6.961	1.152	EPSD	ICGC;COSMIC	5.604	Loss
CAMK_CAMKL_CHK1_CHEK1_ST	Q9UQ35	SRRM2	O14757	CHEK1	S1711	R1705H	1705	Missense	distal	-6	no	6.961	7.071	EPSD	ICGC;COSMIC	5.604	Up-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q9UQ35	SRRM2	O14757	CHEK1	T1720	R1717C	1717	Missense	distal	-3	no	7.375	-0.716	EPSD	ICGC;COSMIC	5.604	Loss
CAMK_CAMKL_CHK1_CHEK1_ST	Q9UQ35	SRRM2	O14757	CHEK1	S1729	P1733L	1733	Missense	distal	4	no	6.212	6.108	EPSD	ICGC;COSMIC	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q9UQ35	SRRM2	O14757	CHEK1	S1762	R1768C	1768	Missense	distal	6	no	7.307	7.601	EPSD	ICGC;COSMIC	5.604	Up-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q9UQ35	SRRM2	O14757	CHEK1	S1762	R1768H	1768	Missense	distal	6	no	7.307	7.595	EPSD	ICGC	5.604	Up-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q9UQ35	SRRM2	O14757	CHEK1	S1762	P1765S	1765	Missense	distal	3	no	7.307	6.978	EPSD	ICGC;COSMIC	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q9UQ35	SRRM2	O14757	CHEK1	S1764	R1768C	1768	Missense	distal	4	no	10.026	10.130	EPSD	ICGC;COSMIC	5.604	Up-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q9UQ35	SRRM2	O14757	CHEK1	S1764	R1768H	1768	Missense	distal	4	no	10.026	10.187	EPSD	ICGC	5.604	Up-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q9UQ35	SRRM2	O14757	CHEK1	S1764	P1765S	1765	Missense	proximal	1	no	10.026	10.062	EPSD	ICGC;COSMIC	5.604	Up-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q9UQ35	SRRM2	O14757	CHEK1	S1775	R1768C	1768	Missense	distal	-7	no	13.234	12.506	EPSD	ICGC;COSMIC	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q9UQ35	SRRM2	O14757	CHEK1	S1775	R1776L	1776	Missense	proximal	1	no	13.234	13.199	EPSD	ICGC	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q9UQ35	SRRM2	O14757	CHEK1	S1775	S1777L	1777	Missense	proximal	2	no	13.234	12.839	EPSD	ICGC;COSMIC;GDSC;CCLE	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q9UQ35	SRRM2	O14757	CHEK1	S1775	R1768H	1768	Missense	distal	-7	no	13.234	13.174	EPSD	ICGC	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q9UQ35	SRRM2	O14757	CHEK1	T1784	S1777L	1777	Missense	distal	-7	no	6.236	5.352	EPSD	ICGC;COSMIC;GDSC;CCLE	5.604	Loss
CAMK_CAMKL_CHK1_CHEK1_ST	Q9UQ35	SRRM2	O14757	CHEK1	S1791	Q1795H	1795	Missense	distal	4	no	9.800	9.961	EPSD	ICGC;COSMIC	5.604	Up-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q9UQ35	SRRM2	O14757	CHEK1	S1793	Q1795H	1795	Missense	proximal	2	no	10.373	9.863	EPSD	ICGC;COSMIC	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q9UQ35	SRRM2	O14757	CHEK1	S1818	R1813W	1813	Missense	distal	-5	no	9.078	8.219	EPSD	ICGC	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q9UQ35	SRRM2	O14757	CHEK1	S1818	R1813L	1813	Missense	distal	-5	no	9.078	12.055	EPSD	ICGC	5.604	Up-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q9UQ35	SRRM2	O14757	CHEK1	S1818	R1823S	1823	Missense	distal	5	no	9.078	9.181	EPSD	ICGC	5.604	Up-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q9UQ35	SRRM2	O14757	CHEK1	S1818	R1814L	1814	Missense	distal	-4	no	9.078	8.822	EPSD	ICGC	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q9UQ35	SRRM2	O14757	CHEK1	S1818	G1819V	1819	Missense	proximal	1	no	9.078	9.054	EPSD	ICGC;COSMIC	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q9UQ35	SRRM2	O14757	CHEK1	S1830	R1837H	1837	Missense	distal	7	no	8.697	8.404	EPSD	ICGC;COSMIC	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q9UQ35	SRRM2	O14757	CHEK1	S1830	A1826V	1826	Missense	distal	-4	no	8.697	8.618	EPSD	ICGC	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q9UQ35	SRRM2	O14757	CHEK1	S1830	R1823S	1823	Missense	distal	-7	no	8.697	8.956	EPSD	ICGC	5.604	Up-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q9UQ35	SRRM2	O14757	CHEK1	S1830	S1831F	1831	Missense	proximal	1	no	8.697	8.692	EPSD	ICGC	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q9UQ35	SRRM2	O14757	CHEK1	S1842	R1837H	1837	Missense	distal	-5	no	9.900	7.435	EPSD	ICGC;COSMIC	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q9UQ35	SRRM2	O14757	CHEK1	S1842	R1843W	1843	Missense	proximal	1	no	9.900	9.870	EPSD	ICGC	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q9UQ35	SRRM2	O14757	CHEK1	T1844	R1837H	1837	Missense	distal	-7	no	8.740	8.681	EPSD	ICGC;COSMIC	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q9UQ35	SRRM2	O14757	CHEK1	T1844	R1851H	1851	Missense	distal	7	no	8.740	8.447	EPSD	ICGC;COSMIC	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q9UQ35	SRRM2	O14757	CHEK1	T1844	R1843W	1843	Missense	proximal	-1	no	8.740	8.857	EPSD	ICGC	5.604	Up-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q9UQ35	SRRM2	O14757	CHEK1	S1852	T1856I	1856	Missense	distal	4	no	8.816	8.856	EPSD	ICGC;COSMIC	5.604	Up-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q9UQ35	SRRM2	O14757	CHEK1	S1852	R1851H	1851	Missense	proximal	-1	no	8.816	8.942	EPSD	ICGC;COSMIC	5.604	Up-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q9UQ35	SRRM2	O14757	CHEK1	S1854	T1856I	1856	Missense	proximal	2	no	8.432	8.317	EPSD	ICGC;COSMIC	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q9UQ35	SRRM2	O14757	CHEK1	S1854	R1851H	1851	Missense	distal	-3	no	8.432	2.623	EPSD	ICGC;COSMIC	5.604	Loss
CAMK_CAMKL_CHK1_CHEK1_ST	Q9UQ35	SRRM2	O14757	CHEK1	T1856	T1856I	1856	Missense	central	0	yes	8.195	0.000	EPSD	ICGC;COSMIC	5.604	Loss
CAMK_CAMKL_CHK1_CHEK1_ST	Q9UQ35	SRRM2	O14757	CHEK1	T1856	R1851H	1851	Missense	distal	-5	no	8.195	5.730	EPSD	ICGC;COSMIC	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q9UQ35	SRRM2	O14757	CHEK1	T1856	R1863L	1863	Missense	distal	7	no	8.195	8.095	EPSD	ICGC	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q9UQ35	SRRM2	O14757	CHEK1	S1866	R1863L	1863	Missense	distal	-3	no	10.039	-8.508	EPSD	ICGC	5.604	Loss
CAMK_CAMKL_CHK1_CHEK1_ST	Q9UQ35	SRRM2	O14757	CHEK1	S1866	R1865I	1865	Missense	proximal	-1	no	10.039	9.995	EPSD	ICGC	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q9UQ35	SRRM2	O14757	CHEK1	S1878	R1874W	1874	Missense	distal	-4	no	6.953	6.191	EPSD	ICGC;COSMIC	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q9UQ35	SRRM2	O14757	CHEK1	S1878	L1882M	1882	Missense	distal	4	no	6.953	7.027	EPSD	ICGC;COSMIC	5.604	Up-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q9UQ35	SRRM2	O14757	CHEK1	S1878	R1875Q	1875	Missense	distal	-3	no	6.953	-0.254	EPSD	ICGC;COSMIC	5.604	Loss
CAMK_CAMKL_CHK1_CHEK1_ST	Q9UQ35	SRRM2	O14757	CHEK1	T1880	R1874W	1874	Missense	distal	-6	no	6.239	6.559	EPSD	ICGC;COSMIC	5.604	Up-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q9UQ35	SRRM2	O14757	CHEK1	T1880	L1882M	1882	Missense	proximal	2	no	6.239	6.706	EPSD	ICGC;COSMIC	5.604	Up-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q9UQ35	SRRM2	O14757	CHEK1	T1880	R1875Q	1875	Missense	distal	-5	no	6.239	5.843	EPSD	ICGC;COSMIC	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q9UQ35	SRRM2	O14757	CHEK1	S1888	L1882M	1882	Missense	distal	-6	no	10.205	10.243	EPSD	ICGC;COSMIC	5.604	Up-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q9UQ35	SRRM2	O14757	CHEK1	T1892	R1899Q	1899	Missense	distal	7	no	8.214	8.368	EPSD	ICGC;GDSC;CCLE	5.604	Up-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q9UQ35	SRRM2	O14757	CHEK1	S1900	R1899Q	1899	Missense	proximal	-1	no	8.678	8.693	EPSD	ICGC;GDSC;CCLE	5.604	Up-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q9UQ35	SRRM2	O14757	CHEK1	S1902	R1899Q	1899	Missense	distal	-3	no	8.410	1.203	EPSD	ICGC;GDSC;CCLE	5.604	Loss
CAMK_CAMKL_CHK1_CHEK1_ST	Q9UQ35	SRRM2	O14757	CHEK1	T1904	R1910T	1910	Missense	distal	6	no	8.797	9.020	EPSD	ICGC;COSMIC	5.604	Up-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q9UQ35	SRRM2	O14757	CHEK1	T1904	R1899Q	1899	Missense	distal	-5	no	8.797	8.401	EPSD	ICGC;GDSC;CCLE	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q9UQ35	SRRM2	O14757	CHEK1	S1911	R1910T	1910	Missense	proximal	-1	no	10.154	10.197	EPSD	ICGC;COSMIC	5.604	Up-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q9UQ35	SRRM2	O14757	CHEK1	S1911	S1916P	1916	Missense	distal	5	no	10.154	10.072	EPSD	ICGC;COSMIC	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q9UQ35	SRRM2	O14757	CHEK1	S1911	S1916Y	1916	Missense	distal	5	no	10.154	9.700	EPSD	ICGC;COSMIC	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q9UQ35	SRRM2	O14757	CHEK1	S1911	S1913A	1913	Missense	proximal	2	no	10.154	10.610	EPSD	ICGC	5.604	Up-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q9UQ35	SRRM2	O14757	CHEK1	S1913	R1910T	1910	Missense	distal	-3	no	12.021	-8.548	EPSD	ICGC;COSMIC	5.604	Loss
CAMK_CAMKL_CHK1_CHEK1_ST	Q9UQ35	SRRM2	O14757	CHEK1	S1913	S1916P	1916	Missense	distal	3	no	12.021	12.350	EPSD	ICGC;COSMIC	5.604	Up-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q9UQ35	SRRM2	O14757	CHEK1	S1913	S1916Y	1916	Missense	distal	3	no	12.021	10.793	EPSD	ICGC;COSMIC	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q9UQ35	SRRM2	O14757	CHEK1	S1913	S1913A	1913	Missense	central	0	yes	12.021	0.000	EPSD	ICGC	5.604	Loss
CAMK_CAMKL_CHK1_CHEK1_ST	Q9UQ35	SRRM2	O14757	CHEK1	S1923	S1916P	1916	Missense	distal	-7	no	9.000	8.330	EPSD	ICGC;COSMIC	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q9UQ35	SRRM2	O14757	CHEK1	S1923	S1916Y	1916	Missense	distal	-7	no	9.000	7.342	EPSD	ICGC;COSMIC	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q9UQ35	SRRM2	O14757	CHEK1	S1925	R1932H	1932	Missense	distal	7	no	10.440	10.148	EPSD	ICGC;COSMIC;GDSC;CCLE	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q9UQ35	SRRM2	O14757	CHEK1	S1925	R1932S	1932	Missense	distal	7	no	10.440	10.348	EPSD	ICGC;COSMIC	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q9UQ35	SRRM2	O14757	CHEK1	T1927	R1932H	1932	Missense	distal	5	no	9.219	9.235	EPSD	ICGC;COSMIC;GDSC;CCLE	5.604	Up-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q9UQ35	SRRM2	O14757	CHEK1	T1927	R1932S	1932	Missense	distal	5	no	9.219	9.322	EPSD	ICGC;COSMIC	5.604	Up-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q9UQ35	SRRM2	O14757	CHEK1	S1935	T1939M	1939	Missense	distal	4	no	7.026	7.125	EPSD	ICGC;COSMIC	5.604	Up-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q9UQ35	SRRM2	O14757	CHEK1	S1935	R1932H	1932	Missense	distal	-3	no	7.026	1.217	EPSD	ICGC;COSMIC;GDSC;CCLE	5.604	Loss
CAMK_CAMKL_CHK1_CHEK1_ST	Q9UQ35	SRRM2	O14757	CHEK1	S1935	R1932S	1932	Missense	distal	-3	no	7.026	-2.670	EPSD	ICGC;COSMIC	5.604	Loss
CAMK_CAMKL_CHK1_CHEK1_ST	Q9UQ35	SRRM2	O14757	CHEK1	S1937	T1939M	1939	Missense	proximal	2	no	8.934	9.399	EPSD	ICGC;COSMIC	5.604	Up-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q9UQ35	SRRM2	O14757	CHEK1	S1937	R1932H	1932	Missense	distal	-5	no	8.934	6.469	EPSD	ICGC;COSMIC;GDSC;CCLE	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q9UQ35	SRRM2	O14757	CHEK1	S1937	R1932S	1932	Missense	distal	-5	no	8.934	8.723	EPSD	ICGC;COSMIC	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q9UQ35	SRRM2	O14757	CHEK1	T1939	T1939M	1939	Missense	central	0	yes	8.050	0.000	EPSD	ICGC;COSMIC	5.604	Loss
CAMK_CAMKL_CHK1_CHEK1_ST	Q9UQ35	SRRM2	O14757	CHEK1	T1939	R1932H	1932	Missense	distal	-7	no	8.050	7.991	EPSD	ICGC;COSMIC;GDSC;CCLE	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q9UQ35	SRRM2	O14757	CHEK1	T1939	R1932S	1932	Missense	distal	-7	no	8.050	8.309	EPSD	ICGC;COSMIC	5.604	Up-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q9UQ35	SRRM2	O14757	CHEK1	T1941	T1939M	1939	Missense	proximal	-2	no	10.178	10.066	EPSD	ICGC;COSMIC	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q9UQ35	SRRM2	O14757	CHEK1	T1941	R1947C	1947	Missense	distal	6	no	10.178	10.472	EPSD	ICGC;COSMIC	5.604	Up-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q9UQ35	SRRM2	O14757	CHEK1	S1946	T1950P	1950	Missense	distal	4	no	11.287	11.416	EPSD	ICGC;COSMIC	5.604	Up-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q9UQ35	SRRM2	O14757	CHEK1	S1946	T1939M	1939	Missense	distal	-7	no	11.287	11.753	EPSD	ICGC;COSMIC	5.604	Up-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q9UQ35	SRRM2	O14757	CHEK1	S1946	R1947C	1947	Missense	proximal	1	no	11.287	11.277	EPSD	ICGC;COSMIC	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q9UQ35	SRRM2	O14757	CHEK1	S1946	P1951L	1951	Missense	distal	5	no	11.287	11.125	EPSD	ICGC	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q9UQ35	SRRM2	O14757	CHEK1	S1948	T1950P	1950	Missense	proximal	2	no	10.690	11.005	EPSD	ICGC;COSMIC	5.604	Up-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q9UQ35	SRRM2	O14757	CHEK1	S1948	R1947C	1947	Missense	proximal	-1	no	10.690	10.725	EPSD	ICGC;COSMIC	5.604	Up-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q9UQ35	SRRM2	O14757	CHEK1	S1948	P1951L	1951	Missense	distal	3	no	10.690	9.926	EPSD	ICGC	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q9UQ35	SRRM2	O14757	CHEK1	T1950	T1950P	1950	Missense	central	0	yes	9.383	0.000	EPSD	ICGC;COSMIC	5.604	Loss
CAMK_CAMKL_CHK1_CHEK1_ST	Q9UQ35	SRRM2	O14757	CHEK1	T1950	R1947C	1947	Missense	distal	-3	no	9.383	1.292	EPSD	ICGC;COSMIC	5.604	Loss
CAMK_CAMKL_CHK1_CHEK1_ST	Q9UQ35	SRRM2	O14757	CHEK1	T1950	P1951L	1951	Missense	proximal	1	no	9.383	9.411	EPSD	ICGC	5.604	Up-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q9UQ35	SRRM2	O14757	CHEK1	S1958	P1951L	1951	Missense	distal	-7	no	10.255	10.040	EPSD	ICGC	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q9UQ35	SRRM2	O14757	CHEK1	S1972	R1979C	1979	Missense	distal	7	no	9.850	9.444	EPSD	ICGC;COSMIC	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q9UQ35	SRRM2	O14757	CHEK1	T1974	R1979C	1979	Missense	distal	5	no	8.174	7.930	EPSD	ICGC;COSMIC	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q9UQ35	SRRM2	O14757	CHEK1	S1982	R1979C	1979	Missense	distal	-3	no	11.918	3.826	EPSD	ICGC;COSMIC	5.604	Loss
CAMK_CAMKL_CHK1_CHEK1_ST	Q9UQ35	SRRM2	O14757	CHEK1	S1984	R1979C	1979	Missense	distal	-5	no	9.464	8.786	EPSD	ICGC;COSMIC	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q9UQ35	SRRM2	O14757	CHEK1	T1986	R1979C	1979	Missense	distal	-7	no	8.766	8.038	EPSD	ICGC;COSMIC	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q9UQ35	SRRM2	O14757	CHEK1	S1994	R1997C	1997	Missense	distal	3	no	10.602	9.655	EPSD	ICGC;COSMIC	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q9UQ35	SRRM2	O14757	CHEK1	S1994	S1996P	1996	Missense	proximal	2	no	10.602	10.525	EPSD	ICGC;COSMIC	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q9UQ35	SRRM2	O14757	CHEK1	S1996	R1997C	1997	Missense	proximal	1	no	9.955	9.945	EPSD	ICGC;COSMIC	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q9UQ35	SRRM2	O14757	CHEK1	S1996	S1996P	1996	Missense	central	0	yes	9.955	0.000	EPSD	ICGC;COSMIC	5.604	Loss
CAMK_CAMKL_CHK1_CHEK1_ST	Q9UQ35	SRRM2	O14757	CHEK1	T1998	R1997C	1997	Missense	proximal	-1	no	8.160	8.195	EPSD	ICGC;COSMIC	5.604	Up-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q9UQ35	SRRM2	O14757	CHEK1	T1998	S1996P	1996	Missense	proximal	-2	no	8.160	8.444	EPSD	ICGC;COSMIC	5.604	Up-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q9UQ35	SRRM2	O14757	CHEK1	S2006	S2006Y	2006	Missense	central	0	yes	11.305	0.000	EPSD	ICGC;COSMIC	5.604	Loss
CAMK_CAMKL_CHK1_CHEK1_ST	Q9UQ35	SRRM2	O14757	CHEK1	S2008	S2006Y	2006	Missense	proximal	-2	no	10.311	10.423	EPSD	ICGC;COSMIC	5.604	Up-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q9UQ35	SRRM2	O14757	CHEK1	T2010	S2006Y	2006	Missense	distal	-4	no	7.039	6.863	EPSD	ICGC;COSMIC	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q9UQ35	SRRM2	O14757	CHEK1	T2010	R2016C	2016	Missense	distal	6	no	7.039	7.333	EPSD	ICGC	5.604	Up-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q9UQ35	SRRM2	O14757	CHEK1	S2018	S2020F	2020	Missense	proximal	2	no	10.226	10.081	EPSD	ICGC;COSMIC	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q9UQ35	SRRM2	O14757	CHEK1	S2018	A2025S	2025	Missense	distal	7	no	10.226	10.177	EPSD	ICGC;COSMIC	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q9UQ35	SRRM2	O14757	CHEK1	S2018	R2016C	2016	Missense	proximal	-2	no	10.226	10.174	EPSD	ICGC	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q9UQ35	SRRM2	O14757	CHEK1	S2020	S2020F	2020	Missense	central	0	yes	10.148	0.000	EPSD	ICGC;COSMIC	5.604	Loss
CAMK_CAMKL_CHK1_CHEK1_ST	Q9UQ35	SRRM2	O14757	CHEK1	S2020	R2027W	2027	Missense	distal	7	no	10.148	9.647	EPSD	ICGC	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q9UQ35	SRRM2	O14757	CHEK1	S2020	A2025S	2025	Missense	distal	5	no	10.148	10.130	EPSD	ICGC;COSMIC	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q9UQ35	SRRM2	O14757	CHEK1	S2020	R2016C	2016	Missense	distal	-4	no	10.148	9.774	EPSD	ICGC	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q9UQ35	SRRM2	O14757	CHEK1	T2022	S2020F	2020	Missense	proximal	-2	no	7.122	7.412	EPSD	ICGC;COSMIC	5.604	Up-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q9UQ35	SRRM2	O14757	CHEK1	T2022	R2027W	2027	Missense	distal	5	no	7.122	6.954	EPSD	ICGC	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q9UQ35	SRRM2	O14757	CHEK1	T2022	A2025S	2025	Missense	distal	3	no	7.122	7.028	EPSD	ICGC;COSMIC	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q9UQ35	SRRM2	O14757	CHEK1	T2022	R2016C	2016	Missense	distal	-6	no	7.122	7.238	EPSD	ICGC	5.604	Up-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q9UQ35	SRRM2	O14757	CHEK1	S2030	R2027W	2027	Missense	distal	-3	no	8.049	-25.554	EPSD	ICGC	5.604	Loss
CAMK_CAMKL_CHK1_CHEK1_ST	Q9UQ35	SRRM2	O14757	CHEK1	S2030	A2025S	2025	Missense	distal	-5	no	8.049	10.777	EPSD	ICGC;COSMIC	5.604	Up-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q9UQ35	SRRM2	O14757	CHEK1	S2030	T2034M	2034	Missense	distal	4	no	8.049	8.148	EPSD	ICGC;COSMIC	5.604	Up-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q9UQ35	SRRM2	O14757	CHEK1	S2030	S2032Y	2032	Missense	proximal	2	no	8.049	7.752	EPSD	ICGC	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q9UQ35	SRRM2	O14757	CHEK1	S2032	R2027W	2027	Missense	distal	-5	no	12.257	11.398	EPSD	ICGC	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q9UQ35	SRRM2	O14757	CHEK1	S2032	A2025S	2025	Missense	distal	-7	no	12.257	11.807	EPSD	ICGC;COSMIC	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q9UQ35	SRRM2	O14757	CHEK1	S2032	T2034M	2034	Missense	proximal	2	no	12.257	12.722	EPSD	ICGC;COSMIC	5.604	Up-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q9UQ35	SRRM2	O14757	CHEK1	S2032	S2032Y	2032	Missense	central	0	yes	12.257	0.000	EPSD	ICGC	5.604	Loss
CAMK_CAMKL_CHK1_CHEK1_ST	Q9UQ35	SRRM2	O14757	CHEK1	T2034	R2041H	2041	Missense	distal	7	no	6.689	6.396	EPSD	ICGC;COSMIC	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q9UQ35	SRRM2	O14757	CHEK1	T2034	R2027W	2027	Missense	distal	-7	no	6.689	5.143	EPSD	ICGC	5.604	Loss
CAMK_CAMKL_CHK1_CHEK1_ST	Q9UQ35	SRRM2	O14757	CHEK1	T2034	T2034M	2034	Missense	central	0	yes	6.689	0.000	EPSD	ICGC;COSMIC	5.604	Loss
CAMK_CAMKL_CHK1_CHEK1_ST	Q9UQ35	SRRM2	O14757	CHEK1	T2034	S2032Y	2032	Missense	proximal	-2	no	6.689	6.801	EPSD	ICGC	5.604	Up-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q9UQ35	SRRM2	O14757	CHEK1	S2042	R2045H	2045	Missense	distal	3	no	12.881	12.911	EPSD	ICGC	5.604	Up-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q9UQ35	SRRM2	O14757	CHEK1	S2042	R2041H	2041	Missense	proximal	-1	no	12.881	13.006	EPSD	ICGC;COSMIC	5.604	Up-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q9UQ35	SRRM2	O14757	CHEK1	S2042	R2043L	2043	Missense	proximal	1	no	12.881	12.846	EPSD	ICGC;COSMIC	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q9UQ35	SRRM2	O14757	CHEK1	S2044	R2045H	2045	Missense	proximal	1	no	9.101	9.036	EPSD	ICGC	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q9UQ35	SRRM2	O14757	CHEK1	S2044	R2041H	2041	Missense	distal	-3	no	9.101	3.292	EPSD	ICGC;COSMIC	5.604	Loss
CAMK_CAMKL_CHK1_CHEK1_ST	Q9UQ35	SRRM2	O14757	CHEK1	S2044	R2043L	2043	Missense	proximal	-1	no	9.101	9.201	EPSD	ICGC;COSMIC	5.604	Up-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q9UQ35	SRRM2	O14757	CHEK1	S2046	R2045H	2045	Missense	proximal	-1	no	8.169	8.294	EPSD	ICGC	5.604	Up-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q9UQ35	SRRM2	O14757	CHEK1	S2046	R2041H	2041	Missense	distal	-5	no	8.169	5.704	EPSD	ICGC;COSMIC	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q9UQ35	SRRM2	O14757	CHEK1	S2046	R2043L	2043	Missense	distal	-3	no	8.169	-10.378	EPSD	ICGC;COSMIC	5.604	Loss
CAMK_CAMKL_CHK1_CHEK1_ST	Q9UQ35	SRRM2	O14757	CHEK1	S2054	P2059T	2059	Missense	distal	5	no	7.310	7.170	EPSD	ICGC;COSMIC	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q9UQ35	SRRM2	O14757	CHEK1	S2056	A2062T	2062	Missense	distal	6	no	10.857	10.779	EPSD	ICGC	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q9UQ35	SRRM2	O14757	CHEK1	S2056	P2059T	2059	Missense	distal	3	no	10.857	10.384	EPSD	ICGC;COSMIC	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q9UQ35	SRRM2	O14757	CHEK1	T2058	A2062T	2062	Missense	distal	4	no	7.889	7.707	EPSD	ICGC	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q9UQ35	SRRM2	O14757	CHEK1	T2058	P2059T	2059	Missense	proximal	1	no	7.889	7.934	EPSD	ICGC;COSMIC	5.604	Up-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q9UQ35	SRRM2	O14757	CHEK1	T2069	A2062T	2062	Missense	distal	-7	no	9.104	7.787	EPSD	ICGC	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q9UQ35	SRRM2	O14757	CHEK1	S2079	D2086V	2086	Missense	distal	7	no	7.835	7.573	EPSD	ICGC;COSMIC	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q9UQ35	SRRM2	O14757	CHEK1	S2081	D2086V	2086	Missense	distal	5	no	10.233	10.061	EPSD	ICGC;COSMIC	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q9UQ35	SRRM2	O14757	CHEK1	S2081	R2087L	2087	Missense	distal	6	no	10.233	10.555	EPSD	ICGC;COSMIC	5.604	Up-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q9UQ35	SRRM2	O14757	CHEK1	S2090	D2086V	2086	Missense	distal	-4	no	10.934	10.864	EPSD	ICGC;COSMIC	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q9UQ35	SRRM2	O14757	CHEK1	S2090	A2095G	2095	Missense	distal	5	no	10.934	10.725	EPSD	ICGC;COSMIC	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q9UQ35	SRRM2	O14757	CHEK1	S2090	R2087L	2087	Missense	distal	-3	no	10.934	-7.612	EPSD	ICGC;COSMIC	5.604	Loss
CAMK_CAMKL_CHK1_CHEK1_ST	Q9UQ35	SRRM2	O14757	CHEK1	T2092	D2086V	2086	Missense	distal	-6	no	7.816	8.000	EPSD	ICGC;COSMIC	5.604	Up-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q9UQ35	SRRM2	O14757	CHEK1	T2092	A2095G	2095	Missense	distal	3	no	7.816	7.634	EPSD	ICGC;COSMIC	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q9UQ35	SRRM2	O14757	CHEK1	T2092	R2087L	2087	Missense	distal	-5	no	7.816	10.792	EPSD	ICGC;COSMIC	5.604	Up-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q9UQ35	SRRM2	O14757	CHEK1	S2100	A2095G	2095	Missense	distal	-5	no	5.727	8.502	EPSD	ICGC;COSMIC	5.604	Up-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q9UQ35	SRRM2	O14757	CHEK1	S2209	A2205S	2205	Missense	distal	-4	no	10.101	9.721	EPSD	ICGC	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q9UQ35	SRRM2	O14757	CHEK1	S2209	A2206S	2206	Missense	distal	-3	no	10.101	7.116	EPSD	ICGC	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q9UQ35	SRRM2	O14757	CHEK1	S2209	Q2210H	2210	Missense	proximal	1	no	10.101	10.027	EPSD	ICGC	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q9UQ35	SRRM2	O14757	CHEK1	T2316	A2320S	2320	Missense	distal	4	no	6.674	6.480	EPSD	ICGC	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q9UQ35	SRRM2	O14757	CHEK1	S2343	A2346S	2346	Missense	distal	3	no	5.723	5.629	EPSD	ICGC	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q9UQ35	SRRM2	O14757	CHEK1	S2407	S2412Y	2412	Missense	distal	5	no	13.696	13.242	EPSD	ICGC	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q9UQ35	SRRM2	O14757	CHEK1	S2407	P2400S	2400	Missense	distal	-7	no	13.696	14.366	EPSD	ICGC	5.604	Up-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q9UQ35	SRRM2	O14757	CHEK1	T2409	S2412Y	2412	Missense	distal	3	no	6.681	5.454	EPSD	ICGC	5.604	Loss
CAMK_CAMKL_CHK1_CHEK1_ST	Q9UQ35	SRRM2	O14757	CHEK1	T2409	S2415R	2415	Missense	distal	6	no	6.681	6.769	EPSD	ICGC;COSMIC	5.604	Up-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q9UQ35	SRRM2	O14757	CHEK1	S2421	T2420A	2420	Missense	proximal	-1	no	7.443	7.572	EPSD	ICGC;COSMIC	5.604	Up-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q9UQ35	SRRM2	O14757	CHEK1	S2421	S2415R	2415	Missense	distal	-6	no	7.443	7.363	EPSD	ICGC;COSMIC	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q9UQ35	SRRM2	O14757	CHEK1	S2421	P2427T	2427	Missense	distal	6	no	7.443	7.134	EPSD	ICGC;COSMIC	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q9UQ35	SRRM2	O14757	CHEK1	S2421	M2419I	2419	Missense	proximal	-2	no	7.443	7.429	EPSD	ICGC;COSMIC	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q9UQ35	SRRM2	O14757	CHEK1	S2421	T2420I	2420	Missense	proximal	-1	no	7.443	7.356	EPSD	ICGC;COSMIC	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q9UQ35	SRRM2	O14757	CHEK1	S2426	T2420A	2420	Missense	distal	-6	no	9.019	8.824	EPSD	ICGC;COSMIC	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q9UQ35	SRRM2	O14757	CHEK1	S2426	Q2433R	2433	Missense	distal	7	no	9.019	8.864	EPSD	ICGC;COSMIC	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q9UQ35	SRRM2	O14757	CHEK1	S2426	P2427T	2427	Missense	proximal	1	no	9.019	9.063	EPSD	ICGC;COSMIC	5.604	Up-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q9UQ35	SRRM2	O14757	CHEK1	S2426	R2430I	2430	Missense	distal	4	no	9.019	9.020	EPSD	ICGC	5.604	Up-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q9UQ35	SRRM2	O14757	CHEK1	S2426	M2419I	2419	Missense	distal	-7	no	9.019	8.777	EPSD	ICGC;COSMIC	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q9UQ35	SRRM2	O14757	CHEK1	S2426	T2420I	2420	Missense	distal	-6	no	9.019	8.948	EPSD	ICGC;COSMIC	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q9UQ35	SRRM2	O14757	CHEK1	S2436	Q2433R	2433	Missense	distal	-3	no	-0.602	6.605	EPSD	ICGC;COSMIC	5.604	Gain
CAMK_CAMKL_CHK1_CHEK1_ST	Q9UQ35	SRRM2	O14757	CHEK1	T2467	Q2473H	2473	Missense	distal	6	no	5.883	6.178	EPSD	ICGC;COSMIC	5.604	Up-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q9UQ35	SRRM2	O14757	CHEK1	T2467	R2460H	2460	Missense	distal	-7	no	5.883	5.824	EPSD	ICGC;COSMIC;GDSC	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q9UQ35	SRRM2	O14757	CHEK1	T2467	Q2473K	2473	Missense	distal	6	no	5.883	5.802	EPSD	ICGC;COSMIC	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q9UQ35	SRRM2	O14757	CHEK1	S2533	S2538L	2538	Missense	distal	5	no	7.570	7.326	EPSD	ICGC	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q9UQ35	SRRM2	O14757	CHEK1	S2581	V2579F	2579	Missense	proximal	-2	no	10.877	10.975	EPSD	ICGC	5.604	Up-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q9UQ35	SRRM2	O14757	CHEK1	S2581	P2586A	2586	Missense	distal	5	no	10.877	10.977	EPSD	ICGC	5.604	Up-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q9UQ35	SRRM2	O14757	CHEK1	S2581	P2584S	2584	Missense	distal	3	no	10.877	10.547	EPSD	ICGC	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q9UQ35	SRRM2	O14757	CHEK1	S2581	P2582H	2582	Missense	proximal	1	no	10.877	10.874	EPSD	ICGC;COSMIC	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q9UQ35	SRRM2	O14757	CHEK1	S2581	P2586Q	2586	Missense	distal	5	no	10.877	10.931	EPSD	ICGC;COSMIC	5.604	Up-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q9UQ35	SRRM2	O14757	CHEK1	S2581	P2580H	2580	Missense	proximal	-1	no	10.877	10.716	EPSD	ICGC;COSMIC	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q9UQ35	SRRM2	O14757	CHEK1	S2581	A2585S	2585	Missense	distal	4	no	10.877	10.683	EPSD	ICGC;COSMIC	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q9UQ35	SRRM2	O14757	CHEK1	S2608	R2606C	2606	Missense	proximal	-2	no	6.702	6.651	EPSD	ICGC;COSMIC	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q9UQ35	SRRM2	O14757	CHEK1	S2609	R2606C	2606	Missense	distal	-3	no	8.854	0.762	EPSD	ICGC;COSMIC	5.604	Loss
CAMK_CAMKL_CHK1_CHEK1_ST	Q9UQ35	SRRM2	O14757	CHEK1	S2677	R2674G	2674	Missense	distal	-3	no	6.507	-1.268	EPSD	ICGC;COSMIC	5.604	Loss
CAMK_CAMKL_CHK1_CHEK1_ST	Q9UQ35	SRRM2	O14757	CHEK1	S2692	R2689W	2689	Missense	distal	-3	no	6.488	-27.115	EPSD	ICGC;COSMIC	5.604	Loss
CAMK_CAMKL_CHK1_CHEK1_ST	Q9UQ35	SRRM2	O14757	CHEK1	S2692	R2699L	2699	Missense	distal	7	no	6.488	6.387	EPSD	ICGC	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q9UQ35	SRRM2	O14757	CHEK1	S2692	E2697G	2697	Missense	distal	5	no	6.488	6.211	EPSD	ICGC;COSMIC	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q9UQ35	SRRM2	O14757	CHEK1	S2702	D2709Y	2709	Missense	distal	7	no	8.080	7.174	EPSD	ICGC	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q9UQ35	SRRM2	O14757	CHEK1	S2702	R2699L	2699	Missense	distal	-3	no	8.080	-10.467	EPSD	ICGC	5.604	Loss
CAMK_CAMKL_CHK1_CHEK1_ST	Q9UQ35	SRRM2	O14757	CHEK1	S2702	R2708W	2708	Missense	distal	6	no	8.080	8.546	EPSD	ICGC	5.604	Up-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q9UQ35	SRRM2	O14757	CHEK1	S2702	E2697G	2697	Missense	distal	-5	no	8.080	9.301	EPSD	ICGC;COSMIC	5.604	Up-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q9UQ35	SRRM2	O14757	CHEK1	T2738	R2742W	2742	Missense	distal	4	no	8.671	8.734	EPSD	ICGC;COSMIC	5.604	Up-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q9UQ35	SRRM2	O14757	CHEK1	S2748	R2742W	2742	Missense	distal	-6	no	5.978	6.298	EPSD	ICGC;COSMIC	5.604	Up-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q9UQ35	SRRM2	O14757	CHEK1	S2748	R2750S	2750	Missense	proximal	2	no	5.978	6.073	EPSD	ICGC	5.604	Up-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q9P2D1	CHD7	O14757	CHEK1	S417	M422I	422	Missense	distal	5	no	9.414	9.383	EPSD	ICGC;COSMIC	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q9P2D1	CHD7	O14757	CHEK1	T689	A688T	688	Missense	proximal	-1	no	7.870	7.741	EPSD	ICGC;CCLE	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q9P2D1	CHD7	O14757	CHEK1	T689	A688S	688	Missense	proximal	-1	no	7.870	7.537	EPSD	ICGC	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q9P2D1	CHD7	O14757	CHEK1	T1227	G1233S	1233	Missense	distal	6	no	6.721	6.509	PhosphoSitePlus	ICGC;GDSC	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q9P2D1	CHD7	O14757	CHEK1	S1566	K1560Q	1560	Missense	distal	-6	no	8.900	8.993	EPSD	ICGC	5.604	Up-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q9P2D1	CHD7	O14757	CHEK1	T1635	T1641N	1641	Missense	distal	6	no	9.656	9.479	EPSD	ICGC;COSMIC	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q9P2D1	CHD7	O14757	CHEK1	S1882	P1875S	1875	Missense	distal	-7	no	5.307	5.977	EPSD	ICGC;COSMIC	5.604	Gain
CAMK_CAMKL_CHK1_CHEK1_ST	Q9P2D1	CHD7	O14757	CHEK1	S2203	G2200R	2200	Missense	distal	-3	no	-1.086	6.688	EPSD	ICGC;COSMIC	5.604	Gain
CAMK_CAMKL_CHK1_CHEK1_ST	Q9P2D1	CHD7	O14757	CHEK1	T2350	T2353K	2353	Missense	distal	3	no	6.411	7.198	EPSD	ICGC;COSMIC	5.604	Up-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q9P2D1	CHD7	O14757	CHEK1	S2490	R2491L	2491	Missense	proximal	1	no	6.783	6.748	EPSD	ICGC	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q9P2D1	CHD7	O14757	CHEK1	S2490	L2497F	2497	Missense	distal	7	no	6.783	6.361	EPSD	ICGC	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q9P2D1	CHD7	O14757	CHEK1	T2494	R2491L	2491	Missense	distal	-3	no	11.447	-7.099	EPSD	ICGC	5.604	Loss
CAMK_CAMKL_CHK1_CHEK1_ST	Q9P2D1	CHD7	O14757	CHEK1	T2494	L2497F	2497	Missense	distal	3	no	11.447	12.070	EPSD	ICGC	5.604	Up-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q9P2D1	CHD7	O14757	CHEK1	T2705	R2702L	2702	Missense	distal	-3	no	8.993	-9.553	EPSD	ICGC	5.604	Loss
CAMK_CAMKL_CHK1_CHEK1_ST	Q13439	GOLGA4	O14757	CHEK1	S10	K4Q	4	Missense	distal	-6	no	6.808	6.900	EPSD	ICGC;COSMIC	5.604	Up-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q13439	GOLGA4	O14757	CHEK1	S37	R38S	38	Missense	proximal	1	no	8.135	8.110	EPSD	ICGC	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q13439	GOLGA4	O14757	CHEK1	T39	R38S	38	Missense	proximal	-1	no	8.217	8.056	EPSD	ICGC	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q13439	GOLGA4	O14757	CHEK1	S41	R38S	38	Missense	distal	-3	no	6.884	-2.812	EPSD	ICGC	5.604	Loss
CAMK_CAMKL_CHK1_CHEK1_ST	Q13439	GOLGA4	O14757	CHEK1	S71	R77Q	77	Missense	distal	6	no	7.854	7.848	PhosphoSitePlus	ICGC;COSMIC;GDSC;CCLE	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q13439	GOLGA4	O14757	CHEK1	S71	V72M	72	Missense	proximal	1	no	7.854	7.847	PhosphoSitePlus	ICGC;COSMIC	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q13439	GOLGA4	O14757	CHEK1	S89	V94L	94	Missense	distal	5	no	11.344	11.185	EPSD	ICGC;COSMIC	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q13439	GOLGA4	O14757	CHEK1	S89	S87F	87	Missense	proximal	-2	no	11.344	11.634	EPSD	ICGC;COSMIC	5.604	Up-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q13439	GOLGA4	O14757	CHEK1	S89	R95Q	95	Missense	distal	6	no	11.344	11.337	EPSD	ICGC;COSMIC	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q13439	GOLGA4	O14757	CHEK1	S89	R95L	95	Missense	distal	6	no	11.344	11.666	EPSD	ICGC	5.604	Up-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q13439	GOLGA4	O14757	CHEK1	S89	S92C	92	Missense	distal	3	no	11.344	10.394	EPSD	ICGC;COSMIC	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q13439	GOLGA4	O14757	CHEK1	S89	R86W	86	Missense	distal	-3	no	11.344	-22.259	EPSD	ICGC;COSMIC	5.604	Loss
CAMK_CAMKL_CHK1_CHEK1_ST	Q13439	GOLGA4	O14757	CHEK1	S98	V94L	94	Missense	distal	-4	no	13.469	13.221	EPSD	ICGC;COSMIC	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q13439	GOLGA4	O14757	CHEK1	S98	N103S	103	Missense	distal	5	no	13.469	13.471	EPSD	ICGC;COSMIC	5.604	Up-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q13439	GOLGA4	O14757	CHEK1	S98	R95Q	95	Missense	distal	-3	no	13.469	6.262	EPSD	ICGC;COSMIC	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q13439	GOLGA4	O14757	CHEK1	S98	R95L	95	Missense	distal	-3	no	13.469	-5.078	EPSD	ICGC	5.604	Loss
CAMK_CAMKL_CHK1_CHEK1_ST	Q13439	GOLGA4	O14757	CHEK1	S98	S92C	92	Missense	distal	-6	no	13.469	13.504	EPSD	ICGC;COSMIC	5.604	Up-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q13439	GOLGA4	O14757	CHEK1	S98	R104Q	104	Missense	distal	6	no	13.469	13.462	EPSD	ICGC;COSMIC	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q13439	GOLGA4	O14757	CHEK1	S151	R144Q	144	Missense	distal	-7	no	7.434	7.692	EPSD	ICGC;COSMIC	5.604	Up-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q13439	GOLGA4	O14757	CHEK1	S151	R145I	145	Missense	distal	-6	no	7.434	7.512	EPSD	ICGC;COSMIC	5.604	Up-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q13439	GOLGA4	O14757	CHEK1	S179	K173T	173	Missense	distal	-6	no	6.395	6.555	EPSD	ICGC;COSMIC	5.604	Up-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q13439	GOLGA4	O14757	CHEK1	T259	E256K	256	Missense	distal	-3	no	2.413	5.676	EPSD	ICGC;COSMIC	5.604	Gain
CAMK_CAMKL_CHK1_CHEK1_ST	Q13439	GOLGA4	O14757	CHEK1	S1809	Y1808C	1808	Missense	proximal	-1	no	7.128	6.995	EPSD	ICGC;COSMIC	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q13439	GOLGA4	O14757	CHEK1	S1910	H1911R	1911	Missense	proximal	1	no	5.587	5.652	EPSD	ICGC;COSMIC	5.604	Gain
CAMK_CAMKL_CHK1_CHEK1_ST	Q9UEY8	ADD3	O14757	CHEK1	S42	M41I	41	Missense	proximal	-1	no	7.170	7.076	EPSD	ICGC;COSMIC	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q9UEY8	ADD3	O14757	CHEK1	S180	A186T	186	Missense	distal	6	no	10.811	10.733	EPSD	ICGC;COSMIC	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q9UEY8	ADD3	O14757	CHEK1	S180	P176T	176	Missense	distal	-4	no	10.811	10.523	EPSD	ICGC;COSMIC	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q9UEY8	ADD3	O14757	CHEK1	S402	E396K	396	Missense	distal	-6	no	12.112	12.144	EPSD	ICGC;COSMIC	5.604	Up-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q9UEY8	ADD3	O14757	CHEK1	S402	P398R	398	Missense	distal	-4	no	12.112	12.184	EPSD	ICGC;COSMIC	5.604	Up-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q9UEY8	ADD3	O14757	CHEK1	S402	P407T	407	Missense	distal	5	no	12.112	11.972	EPSD	ICGC;COSMIC	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q9UEY8	ADD3	O14757	CHEK1	S693	R690S	690	Missense	distal	-3	no	8.097	-1.599	PhosphoSitePlus	ICGC	5.604	Loss
CAMK_CAMKL_CHK1_CHEK1_ST	Q9BW19	KIFC1	O14757	CHEK1	S71	L72I	72	Missense	proximal	1	no	5.969	5.942	EPSD	ICGC;COSMIC	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q9BW19	KIFC1	O14757	CHEK1	S71	Q77H	77	Missense	distal	6	no	5.969	6.264	EPSD	ICGC	5.604	Up-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q9BW19	KIFC1	O14757	CHEK1	T359	R356Q	356	Missense	distal	-3	no	7.057	-0.150	EPSD	ICGC;COSMIC	5.604	Loss
CAMK_CAMKL_CHK1_CHEK1_ST	Q9BW19	KIFC1	O14757	CHEK1	S648	E645K	645	Missense	distal	-3	no	6.706	9.969	EPSD	ICGC;COSMIC	5.604	Up-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q9BW19	KIFC1	O14757	CHEK1	S648	L654I	654	Missense	distal	6	no	6.706	6.339	EPSD	ICGC;COSMIC	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	P43243	MATR3	O14757	CHEK1	S22	R19C	19	Missense	distal	-3	no	6.427	-1.664	EPSD	ICGC;COSMIC	5.604	Loss
CAMK_CAMKL_CHK1_CHEK1_ST	P43243	MATR3	O14757	CHEK1	S22	D20E	20	Missense	proximal	-2	no	6.427	6.441	EPSD	ICGC;COSMIC	5.604	Up-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	P43243	MATR3	O14757	CHEK1	S54	M56I	56	Missense	proximal	2	no	12.242	11.662	EPSD	ICGC	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	P43243	MATR3	O14757	CHEK1	S63	M56I	56	Missense	distal	-7	no	8.472	8.230	EPSD	ICGC	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	P43243	MATR3	O14757	CHEK1	T150	R149I	149	Missense	proximal	-1	no	10.156	10.112	EPSD;PhosphoSitePlus	ICGC	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	P43243	MATR3	O14757	CHEK1	T166	G162V	162	Missense	distal	-4	no	6.691	6.656	EPSD	ICGC	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	P43243	MATR3	O14757	CHEK1	T166	G159C	159	Missense	distal	-7	no	6.691	5.924	EPSD	ICGC;COSMIC	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	P43243	MATR3	O14757	CHEK1	S195	V199L	199	Missense	distal	4	no	10.722	10.648	PhosphoSitePlus;EPSD	ICGC;COSMIC	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	P43243	MATR3	O14757	CHEK1	S195	D201Y	201	Missense	distal	6	no	10.722	11.648	PhosphoSitePlus;EPSD	ICGC	5.604	Up-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	P43243	MATR3	O14757	CHEK1	S234	C230F	230	Missense	distal	-4	no	6.706	6.530	EPSD	ICGC	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	P43243	MATR3	O14757	CHEK1	S234	S240W	240	Missense	distal	6	no	6.706	7.260	EPSD	ICGC;COSMIC	5.604	Up-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	P43243	MATR3	O14757	CHEK1	S248	H244Q	244	Missense	distal	-4	no	6.962	7.319	EPSD	ICGC;COSMIC	5.604	Up-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	P43243	MATR3	O14757	CHEK1	S307	S307I	307	Missense	central	0	yes	6.619	0.000	EPSD	ICGC	5.604	Loss
CAMK_CAMKL_CHK1_CHEK1_ST	P43243	MATR3	O14757	CHEK1	T396	R393T	393	Missense	distal	-3	no	7.798	-12.771	EPSD	ICGC;COSMIC	5.604	Loss
CAMK_CAMKL_CHK1_CHEK1_ST	P43243	MATR3	O14757	CHEK1	T396	S397I	397	Missense	proximal	1	no	7.798	7.763	EPSD	ICGC	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	P43243	MATR3	O14757	CHEK1	S533	R530M	530	Missense	distal	-3	no	11.499	6.351	EPSD	ICGC	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	P43243	MATR3	O14757	CHEK1	S533	I527T	527	Missense	distal	-6	no	11.499	11.570	EPSD	ICGC;COSMIC	5.604	Up-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	P43243	MATR3	O14757	CHEK1	S592	R595G	595	Missense	distal	3	no	6.533	6.448	EPSD	ICGC;COSMIC	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	P43243	MATR3	O14757	CHEK1	S592	R595I	595	Missense	distal	3	no	6.533	6.161	EPSD	ICGC	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	P43243	MATR3	O14757	CHEK1	S592	S598Y	598	Missense	distal	6	no	6.533	7.275	EPSD	ICGC;COSMIC	5.604	Up-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	P43243	MATR3	O14757	CHEK1	S592	D585N	585	Missense	distal	-7	no	6.533	6.226	EPSD	ICGC;COSMIC	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	P43243	MATR3	O14757	CHEK1	S596	R595G	595	Missense	proximal	-1	no	10.374	10.391	EPSD	ICGC;COSMIC	5.604	Up-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	P43243	MATR3	O14757	CHEK1	S596	R595I	595	Missense	proximal	-1	no	10.374	10.330	EPSD	ICGC	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	P43243	MATR3	O14757	CHEK1	S596	S598Y	598	Missense	proximal	2	no	10.374	10.077	EPSD	ICGC;COSMIC	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	P43243	MATR3	O14757	CHEK1	S598	R595G	595	Missense	distal	-3	no	8.638	0.864	EPSD	ICGC;COSMIC	5.604	Loss
CAMK_CAMKL_CHK1_CHEK1_ST	P43243	MATR3	O14757	CHEK1	S598	R595I	595	Missense	distal	-3	no	8.638	-0.120	EPSD	ICGC	5.604	Loss
CAMK_CAMKL_CHK1_CHEK1_ST	P43243	MATR3	O14757	CHEK1	S598	P605Q	605	Missense	distal	7	no	8.638	8.831	EPSD	ICGC;COSMIC	5.604	Up-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	P43243	MATR3	O14757	CHEK1	S598	S598Y	598	Missense	central	0	yes	8.638	0.000	EPSD	ICGC;COSMIC	5.604	Loss
CAMK_CAMKL_CHK1_CHEK1_ST	Q96T58	SPEN	O14757	CHEK1	S43	G42V	42	Missense	proximal	-1	no	10.511	10.588	EPSD	ICGC	5.604	Up-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q96T58	SPEN	O14757	CHEK1	S43	S43P	43	Missense	central	0	yes	10.511	0.000	EPSD	ICGC;COSMIC	5.604	Loss
CAMK_CAMKL_CHK1_CHEK1_ST	Q96T58	SPEN	O14757	CHEK1	S43	R41M	41	Missense	proximal	-2	no	10.511	10.554	EPSD	ICGC;COSMIC	5.604	Up-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q96T58	SPEN	O14757	CHEK1	S190	S190I	190	Missense	central	0	yes	6.239	0.000	EPSD	ICGC;COSMIC	5.604	Loss
CAMK_CAMKL_CHK1_CHEK1_ST	Q96T58	SPEN	O14757	CHEK1	S190	R187L	187	Missense	distal	-3	no	6.239	-12.307	EPSD	ICGC;COSMIC	5.604	Loss
CAMK_CAMKL_CHK1_CHEK1_ST	Q96T58	SPEN	O14757	CHEK1	S190	R187Q	187	Missense	distal	-3	no	6.239	-0.967	EPSD	ICGC;COSMIC	5.604	Loss
CAMK_CAMKL_CHK1_CHEK1_ST	Q96T58	SPEN	O14757	CHEK1	S244	R251T	251	Missense	distal	7	no	6.042	5.883	EPSD	ICGC;COSMIC	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q96T58	SPEN	O14757	CHEK1	S260	Q261K	261	Missense	proximal	1	no	8.135	8.127	EPSD	ICGC;COSMIC	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q96T58	SPEN	O14757	CHEK1	S260	T266R	266	Missense	distal	6	no	8.135	7.913	EPSD	ICGC;COSMIC	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q96T58	SPEN	O14757	CHEK1	S260	S260N	260	Missense	central	0	yes	8.135	0.000	EPSD	ICGC;COSMIC	5.604	Loss
CAMK_CAMKL_CHK1_CHEK1_ST	Q96T58	SPEN	O14757	CHEK1	S270	T266R	266	Missense	distal	-4	no	5.461	5.820	EPSD	ICGC;COSMIC	5.604	Gain
CAMK_CAMKL_CHK1_CHEK1_ST	Q96T58	SPEN	O14757	CHEK1	S270	G273V	273	Missense	distal	3	no	5.461	5.887	EPSD	ICGC	5.604	Gain
CAMK_CAMKL_CHK1_CHEK1_ST	Q96T58	SPEN	O14757	CHEK1	S278	R275K	275	Missense	distal	-3	no	7.149	3.324	EPSD	ICGC;COSMIC	5.604	Loss
CAMK_CAMKL_CHK1_CHEK1_ST	Q96T58	SPEN	O14757	CHEK1	S278	G273S	273	Missense	distal	-5	no	7.149	7.103	EPSD	ICGC;COSMIC	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q96T58	SPEN	O14757	CHEK1	S278	G271C	271	Missense	distal	-7	no	7.149	6.383	EPSD	ICGC;COSMIC	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q96T58	SPEN	O14757	CHEK1	S278	G273V	273	Missense	distal	-5	no	7.149	6.814	EPSD	ICGC	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q96T58	SPEN	O14757	CHEK1	S623	R620Q	620	Missense	distal	-3	no	7.308	0.101	EPSD	ICGC;COSMIC	5.604	Loss
CAMK_CAMKL_CHK1_CHEK1_ST	Q96T58	SPEN	O14757	CHEK1	S646	R648W	648	Missense	proximal	2	no	6.338	6.163	EPSD	ICGC;COSMIC	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q96T58	SPEN	O14757	CHEK1	S646	Y650S	650	Missense	distal	4	no	6.338	6.163	EPSD	ICGC;COSMIC	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q96T58	SPEN	O14757	CHEK1	S646	S646F	646	Missense	central	0	yes	6.338	0.000	EPSD	ICGC;COSMIC	5.604	Loss
CAMK_CAMKL_CHK1_CHEK1_ST	Q96T58	SPEN	O14757	CHEK1	S727	Q726E	726	Missense	proximal	-1	no	8.901	8.795	EPSD	ICGC;COSMIC	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q96T58	SPEN	O14757	CHEK1	S736	Q735H	735	Missense	proximal	-1	no	13.238	13.348	EPSD	ICGC;COSMIC	5.604	Up-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q96T58	SPEN	O14757	CHEK1	S830	R824L	824	Missense	distal	-6	no	6.492	6.596	EPSD	ICGC	5.604	Up-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q96T58	SPEN	O14757	CHEK1	S830	P831T	831	Missense	proximal	1	no	6.492	6.536	EPSD	ICGC;COSMIC	5.604	Up-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q96T58	SPEN	O14757	CHEK1	S832	T838M	838	Missense	distal	6	no	6.015	6.105	EPSD	ICGC;COSMIC	5.604	Up-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q96T58	SPEN	O14757	CHEK1	S832	P831T	831	Missense	proximal	-1	no	6.015	5.772	EPSD	ICGC;COSMIC	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q96T58	SPEN	O14757	CHEK1	T1059	A1061T	1061	Missense	proximal	2	no	12.296	11.448	PhosphoSitePlus	ICGC;COSMIC	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q96T58	SPEN	O14757	CHEK1	T1140	S1145L	1145	Missense	distal	5	no	5.971	5.727	EPSD	ICGC;COSMIC	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q96T58	SPEN	O14757	CHEK1	T1140	S1135I	1135	Missense	distal	-5	no	5.971	7.128	EPSD	ICGC	5.604	Up-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q96T58	SPEN	O14757	CHEK1	S1194	E1201K	1201	Missense	distal	7	no	7.605	7.440	EPSD	ICGC;COSMIC	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q96T58	SPEN	O14757	CHEK1	S1268	S1263I	1263	Missense	distal	-5	no	9.381	10.537	EPSD	ICGC;COSMIC	5.604	Up-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q96T58	SPEN	O14757	CHEK1	S1283	P1279H	1279	Missense	distal	-4	no	7.283	7.158	EPSD	ICGC;COSMIC	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q96T58	SPEN	O14757	CHEK1	S1306	P1311S	1311	Missense	distal	5	no	7.820	7.902	EPSD	ICGC;COSMIC;GDSC;CCLE	5.604	Up-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q96T58	SPEN	O14757	CHEK1	S1306	F1309C	1309	Missense	distal	3	no	7.820	6.682	EPSD	ICGC;COSMIC;GDSC;CCLE	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q96T58	SPEN	O14757	CHEK1	S1369	S1369F	1369	Missense	central	0	yes	9.734	0.000	EPSD	ICGC;COSMIC	5.604	Loss
CAMK_CAMKL_CHK1_CHEK1_ST	Q96T58	SPEN	O14757	CHEK1	S1369	P1375A	1375	Missense	distal	6	no	9.734	9.502	EPSD	ICGC;COSMIC	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q96T58	SPEN	O14757	CHEK1	S1369	R1362I	1362	Missense	distal	-7	no	9.734	9.350	EPSD	ICGC;COSMIC	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q96T58	SPEN	O14757	CHEK1	S1453	A1451V	1451	Missense	proximal	-2	no	13.331	13.408	EPSD	ICGC;COSMIC	5.604	Up-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q96T58	SPEN	O14757	CHEK1	S1453	E1449G	1449	Missense	distal	-4	no	13.331	13.154	EPSD	ICGC;COSMIC	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q96T58	SPEN	O14757	CHEK1	S1485	D1479H	1479	Missense	distal	-6	no	9.113	9.315	EPSD	ICGC;COSMIC	5.604	Up-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q96T58	SPEN	O14757	CHEK1	S1485	V1483A	1483	Missense	proximal	-2	no	9.113	9.036	EPSD	ICGC;COSMIC	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q96T58	SPEN	O14757	CHEK1	S1485	A1486T	1486	Missense	proximal	1	no	9.113	9.103	EPSD	ICGC;COSMIC	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q96T58	SPEN	O14757	CHEK1	S1641	G1638R	1638	Missense	distal	-3	no	-0.399	7.376	EPSD	ICGC;COSMIC	5.604	Gain
CAMK_CAMKL_CHK1_CHEK1_ST	Q96T58	SPEN	O14757	CHEK1	T1826	R1823H	1823	Missense	distal	-3	no	7.038	1.229	EPSD	ICGC;COSMIC	5.604	Loss
CAMK_CAMKL_CHK1_CHEK1_ST	Q96T58	SPEN	O14757	CHEK1	S1857	R1854W	1854	Missense	distal	-3	no	11.825	-21.779	EPSD	ICGC	5.604	Loss
CAMK_CAMKL_CHK1_CHEK1_ST	Q96T58	SPEN	O14757	CHEK1	S1857	R1854P	1854	Missense	distal	-3	no	11.825	4.688	EPSD	ICGC;COSMIC	5.604	Loss
CAMK_CAMKL_CHK1_CHEK1_ST	Q96T58	SPEN	O14757	CHEK1	S1857	S1857Y	1857	Missense	central	0	yes	11.825	0.000	EPSD	ICGC;COSMIC	5.604	Loss
CAMK_CAMKL_CHK1_CHEK1_ST	Q96T58	SPEN	O14757	CHEK1	S2305	S2305I	2305	Missense	central	0	yes	6.146	0.000	EPSD	ICGC	5.604	Loss
CAMK_CAMKL_CHK1_CHEK1_ST	Q96T58	SPEN	O14757	CHEK1	T2423	S2426T	2426	Missense	distal	3	no	6.850	6.706	EPSD	ICGC;COSMIC	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q96T58	SPEN	O14757	CHEK1	S2452	D2457N	2457	Missense	distal	5	no	10.929	10.840	EPSD	ICGC;COSMIC	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q96T58	SPEN	O14757	CHEK1	T2471	P2468R	2468	Missense	distal	-3	no	2.655	9.792	EPSD	ICGC;COSMIC	5.604	Gain
CAMK_CAMKL_CHK1_CHEK1_ST	Q96T58	SPEN	O14757	CHEK1	S2778	Q2775H	2775	Missense	distal	-3	no	4.436	5.833	EPSD	ICGC;COSMIC	5.604	Gain
CAMK_CAMKL_CHK1_CHEK1_ST	Q96T58	SPEN	O14757	CHEK1	S2860	Q2855K	2855	Missense	distal	-5	no	6.934	8.506	EPSD	ICGC;COSMIC	5.604	Up-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q96T58	SPEN	O14757	CHEK1	S2860	S2860Y	2860	Missense	central	0	yes	6.934	0.000	EPSD	ICGC;COSMIC	5.604	Loss
CAMK_CAMKL_CHK1_CHEK1_ST	Q96T58	SPEN	O14757	CHEK1	T3102	T3109N	3109	Missense	distal	7	no	6.301	6.597	EPSD	ICGC	5.604	Up-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q96T58	SPEN	O14757	CHEK1	T3102	Q3095K	3095	Missense	distal	-7	no	6.301	7.223	EPSD	ICGC;COSMIC	5.604	Up-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q96T58	SPEN	O14757	CHEK1	T3139	A3133T	3133	Missense	distal	-6	no	6.682	6.878	EPSD	ICGC	5.604	Up-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q96T58	SPEN	O14757	CHEK1	T3568	T3568M	3568	Missense	central	0	yes	7.244	0.000	EPSD	ICGC;COSMIC	5.604	Loss
CAMK_CAMKL_CHK1_CHEK1_ST	Q96T58	SPEN	O14757	CHEK1	T3568	Y3573C	3573	Missense	distal	5	no	7.244	7.351	EPSD	ICGC;COSMIC	5.604	Up-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q96T58	SPEN	O14757	CHEK1	T3568	M3567I	3567	Missense	proximal	-1	no	7.244	7.150	EPSD	ICGC;COSMIC	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q9NRM7	LATS2	O14757	CHEK1	T5	A8D	8	Missense	distal	3	no	6.148	7.611	EPSD	ICGC	5.604	Up-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q9NRM7	LATS2	O14757	CHEK1	T5	T9K	9	Missense	distal	4	no	6.148	6.089	EPSD	ICGC	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q9NRM7	LATS2	O14757	CHEK1	S172	S179L	179	Missense	distal	7	no	6.543	6.535	EPSD	ICGC;COSMIC	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q9NRM7	LATS2	O14757	CHEK1	S172	R169W	169	Missense	distal	-3	no	6.543	-27.061	EPSD	ICGC	5.604	Loss
CAMK_CAMKL_CHK1_CHEK1_ST	Q9NRM7	LATS2	O14757	CHEK1	S172	P171H	171	Missense	proximal	-1	no	6.543	6.382	EPSD	ICGC	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q9NRM7	LATS2	O14757	CHEK1	S172	T168K	168	Missense	distal	-4	no	6.543	7.003	EPSD	ICGC	5.604	Up-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q9NRM7	LATS2	O14757	CHEK1	S172	P166T	166	Missense	distal	-6	no	6.543	6.515	EPSD	ICGC;COSMIC	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q9NRM7	LATS2	O14757	CHEK1	S274	R271C	271	Missense	distal	-3	no	8.401	0.309	EPSD	ICGC	5.604	Loss
CAMK_CAMKL_CHK1_CHEK1_ST	Q9NRM7	LATS2	O14757	CHEK1	S274	V269A	269	Missense	distal	-5	no	8.401	5.961	EPSD	ICGC;COSMIC	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q9NRM7	LATS2	O14757	CHEK1	S380	P384L	384	Missense	distal	4	no	16.516	16.412	EPSD	ICGC;COSMIC;GDSC	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q9NRM7	LATS2	O14757	CHEK1	S380	E387G	387	Missense	distal	7	no	16.516	16.281	EPSD	ICGC	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q9NRM7	LATS2	O14757	CHEK1	S446	R448C	448	Missense	proximal	2	no	6.887	6.621	EPSD	ICGC;COSMIC	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q9NRM7	LATS2	O14757	CHEK1	S835	S835R	835	Missense	central	0	yes	7.876	0.000	PhosphoSitePlus;EPSD	ICGC	5.604	Loss
CAMK_CAMKL_CHK1_CHEK1_ST	Q9NRM7	LATS2	O14757	CHEK1	S839	S835R	835	Missense	distal	-4	no	5.616	5.924	EPSD	ICGC	5.604	Up-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q5UIP0	RIF1	O14757	CHEK1	S740	S735F	735	Missense	distal	-5	no	7.255	6.880	EPSD	ICGC;COSMIC	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q5UIP0	RIF1	O14757	CHEK1	S802	L806R	806	Missense	distal	4	no	10.559	10.573	EPSD	ICGC;COSMIC	5.604	Up-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q5UIP0	RIF1	O14757	CHEK1	S818	D825Y	825	Missense	distal	7	no	6.874	5.968	EPSD	ICGC	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q5UIP0	RIF1	O14757	CHEK1	S1184	S1180L	1180	Missense	distal	-4	no	7.967	8.019	EPSD	ICGC;COSMIC	5.604	Up-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q5UIP0	RIF1	O14757	CHEK1	S1184	S1189F	1189	Missense	distal	5	no	7.967	7.642	EPSD	ICGC;COSMIC	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q5UIP0	RIF1	O14757	CHEK1	T1220	T1223A	1223	Missense	distal	3	no	5.470	5.707	EPSD	ICGC	5.604	Gain
CAMK_CAMKL_CHK1_CHEK1_ST	Q5UIP0	RIF1	O14757	CHEK1	T1220	S1216N	1216	Missense	distal	-4	no	5.470	5.764	EPSD	ICGC	5.604	Gain
CAMK_CAMKL_CHK1_CHEK1_ST	Q5UIP0	RIF1	O14757	CHEK1	S1236	S1238F	1238	Missense	proximal	2	no	7.864	7.720	EPSD	ICGC;COSMIC	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q5UIP0	RIF1	O14757	CHEK1	S1236	R1233I	1233	Missense	distal	-3	no	7.864	-0.894	EPSD	ICGC	5.604	Loss
CAMK_CAMKL_CHK1_CHEK1_ST	Q5UIP0	RIF1	O14757	CHEK1	S1236	P1239L	1239	Missense	distal	3	no	7.864	7.101	EPSD	ICGC	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q5UIP0	RIF1	O14757	CHEK1	T1372	N1371Y	1371	Missense	proximal	-1	no	7.207	7.318	EPSD	ICGC;COSMIC	5.604	Up-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q5UIP0	RIF1	O14757	CHEK1	S1418	K1412E	1412	Missense	distal	-6	no	8.615	8.583	EPSD	ICGC;COSMIC	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q5UIP0	RIF1	O14757	CHEK1	S1437	D1433H	1433	Missense	distal	-4	no	7.019	6.759	EPSD	ICGC;COSMIC	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q5UIP0	RIF1	O14757	CHEK1	S1437	R1444G	1444	Missense	distal	7	no	7.019	7.025	EPSD	ICGC;COSMIC	5.604	Up-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q5UIP0	RIF1	O14757	CHEK1	S1437	R1443L	1443	Missense	distal	6	no	7.019	7.341	EPSD	ICGC;COSMIC	5.604	Up-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q5UIP0	RIF1	O14757	CHEK1	T1534	Q1537P	1537	Missense	distal	3	no	11.148	10.418	EPSD	ICGC	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q5UIP0	RIF1	O14757	CHEK1	T1538	Q1537P	1537	Missense	proximal	-1	no	7.580	7.850	EPSD	ICGC	5.604	Up-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q5UIP0	RIF1	O14757	CHEK1	S1542	Q1537P	1537	Missense	distal	-5	no	5.816	4.482	EPSD	ICGC	5.604	Loss
CAMK_CAMKL_CHK1_CHEK1_ST	Q5UIP0	RIF1	O14757	CHEK1	T1656	E1651D	1651	Missense	distal	-5	no	6.845	7.245	EPSD	ICGC;COSMIC	5.604	Up-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q5UIP0	RIF1	O14757	CHEK1	S1688	L1694F	1694	Missense	distal	6	no	8.193	8.187	EPSD	ICGC;COSMIC	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q5UIP0	RIF1	O14757	CHEK1	S1793	G1799V	1799	Missense	distal	6	no	6.332	6.396	EPSD	ICGC;COSMIC	5.604	Up-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q5UIP0	RIF1	O14757	CHEK1	T1822	T1816I	1816	Missense	distal	-6	no	7.091	7.020	EPSD	ICGC;COSMIC	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q5UIP0	RIF1	O14757	CHEK1	S2205	Y2211H	2211	Missense	distal	6	no	12.302	11.936	PhosphoSitePlus	ICGC	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q5UIP0	RIF1	O14757	CHEK1	S2205	R2202H	2202	Missense	distal	-3	no	12.302	6.493	PhosphoSitePlus	ICGC;COSMIC	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q5UIP0	RIF1	O14757	CHEK1	S2205	I2210V	2210	Missense	distal	5	no	12.302	12.361	PhosphoSitePlus	ICGC;COSMIC	5.604	Up-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q5UIP0	RIF1	O14757	CHEK1	S2205	N2199H	2199	Missense	distal	-6	no	12.302	12.291	PhosphoSitePlus	ICGC;COSMIC	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q5UIP0	RIF1	O14757	CHEK1	S2224	R2221K	2221	Missense	distal	-3	no	8.876	5.050	EPSD	ICGC;COSMIC	5.604	Loss
CAMK_CAMKL_CHK1_CHEK1_ST	Q5UIP0	RIF1	O14757	CHEK1	S2230	I2236K	2236	Missense	distal	6	no	9.819	9.776	EPSD	ICGC;COSMIC	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q5UIP0	RIF1	O14757	CHEK1	S2230	I2236V	2236	Missense	distal	6	no	9.819	10.052	EPSD	ICGC	5.604	Up-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q5UIP0	RIF1	O14757	CHEK1	S2393	L2392V	2392	Missense	proximal	-1	no	6.016	6.010	EPSD	ICGC;COSMIC	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q9NXE8	CWC25	O14757	CHEK1	S288	R282W	282	Missense	distal	-6	no	6.871	7.191	EPSD	ICGC	5.604	Up-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q9NXE8	CWC25	O14757	CHEK1	T311	R309W	309	Missense	proximal	-2	no	10.509	10.631	EPSD	ICGC	5.604	Up-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q96PK6	RBM14	O14757	CHEK1	T206	R203S	203	Missense	distal	-3	no	7.813	-1.883	EPSD	ICGC;COSMIC	5.604	Loss
CAMK_CAMKL_CHK1_CHEK1_ST	Q96PK6	RBM14	O14757	CHEK1	T206	R203C	203	Missense	distal	-3	no	7.813	-0.278	EPSD	ICGC;COSMIC	5.604	Loss
CAMK_CAMKL_CHK1_CHEK1_ST	Q96PK6	RBM14	O14757	CHEK1	T206	P208S	208	Missense	proximal	2	no	7.813	7.890	EPSD	ICGC	5.604	Up-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q96PK6	RBM14	O14757	CHEK1	S215	R214L	214	Missense	proximal	-1	no	10.265	10.365	EPSD	ICGC;COSMIC	5.604	Up-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q96PK6	RBM14	O14757	CHEK1	S215	R218H	218	Missense	distal	3	no	10.265	10.296	EPSD	ICGC	5.604	Up-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q96PK6	RBM14	O14757	CHEK1	S215	P208S	208	Missense	distal	-7	no	10.265	10.935	EPSD	ICGC	5.604	Up-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q96PK6	RBM14	O14757	CHEK1	T231	S225C	225	Missense	distal	-6	no	6.366	6.402	EPSD	ICGC;COSMIC	5.604	Up-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q96PK6	RBM14	O14757	CHEK1	T231	R238W	238	Missense	distal	7	no	6.366	5.865	EPSD	ICGC;COSMIC	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q96PK6	RBM14	O14757	CHEK1	S520	S527T	527	Missense	distal	7	no	10.194	10.127	EPSD	ICGC;COSMIC	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q96PK6	RBM14	O14757	CHEK1	S520	A514T	514	Missense	distal	-6	no	10.194	10.389	EPSD	ICGC;COSMIC	5.604	Up-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q96PK6	RBM14	O14757	CHEK1	S560	A567V	567	Missense	distal	7	no	7.634	7.713	EPSD	ICGC	5.604	Up-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q96PK6	RBM14	O14757	CHEK1	S560	A557T	557	Missense	distal	-3	no	7.634	-6.223	EPSD	ICGC;COSMIC	5.604	Loss
CAMK_CAMKL_CHK1_CHEK1_ST	Q96PK6	RBM14	O14757	CHEK1	S560	G564E	564	Missense	distal	4	no	7.634	7.525	EPSD	ICGC;COSMIC	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q96PK6	RBM14	O14757	CHEK1	S618	Y614C	614	Missense	distal	-4	no	7.059	7.170	EPSD;PhosphoSitePlus	ICGC;COSMIC	5.604	Up-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	O14757	CHEK1	O14757	CHEK1	T378	R376I	376	Missense	proximal	-2	no	6.209	6.238	PhosphoSitePlus	ICGC	5.604	Up-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	O14757	CHEK1	O14757	CHEK1	T378	R379L	379	Missense	proximal	1	no	6.209	6.175	PhosphoSitePlus	ICGC	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	O14757	CHEK1	O14757	CHEK1	T378	M377V	377	Missense	proximal	-1	no	6.209	6.253	PhosphoSitePlus	ICGC;COSMIC	5.604	Up-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q9H8G2	CAAP1	O14757	CHEK1	S7	R8L	8	Missense	proximal	1	no	5.962	5.927	EPSD	ICGC;COSMIC	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q9H8G2	CAAP1	O14757	CHEK1	S7	K5E	5	Missense	proximal	-2	no	5.962	6.105	EPSD	ICGC;COSMIC	5.604	Up-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q9H8G2	CAAP1	O14757	CHEK1	S7	R12S	12	Missense	distal	5	no	5.962	6.065	EPSD	ICGC	5.604	Up-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q9Y520	PRRC2C	O14757	CHEK1	S191	S191L	191	Missense	central	0	yes	7.641	0.000	EPSD	ICGC;COSMIC	5.604	Loss
CAMK_CAMKL_CHK1_CHEK1_ST	Q9Y520	PRRC2C	O14757	CHEK1	S500	P501A	501	Missense	proximal	1	no	8.114	8.168	EPSD	ICGC;COSMIC	5.604	Up-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q9Y520	PRRC2C	O14757	CHEK1	T826	E830D	830	Missense	distal	4	no	6.156	6.248	EPSD	ICGC	5.604	Up-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q9Y520	PRRC2C	O14757	CHEK1	S924	R923Q	923	Missense	proximal	-1	no	8.986	9.001	EPSD	ICGC;COSMIC	5.604	Up-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q9Y520	PRRC2C	O14757	CHEK1	S926	R923Q	923	Missense	distal	-3	no	9.532	2.325	EPSD	ICGC;COSMIC	5.604	Loss
CAMK_CAMKL_CHK1_CHEK1_ST	Q9Y520	PRRC2C	O14757	CHEK1	T1215	R1209C	1209	Missense	distal	-6	no	9.178	9.294	EPSD	ICGC;COSMIC	5.604	Up-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q9Y520	PRRC2C	O14757	CHEK1	S1242	E1243K	1243	Missense	proximal	1	no	7.926	7.852	EPSD	ICGC;COSMIC	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q9Y520	PRRC2C	O14757	CHEK1	S1242	S1248C	1248	Missense	distal	6	no	7.926	8.307	EPSD	ICGC;COSMIC	5.604	Up-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q9Y520	PRRC2C	O14757	CHEK1	S1248	E1243K	1243	Missense	distal	-5	no	7.198	9.760	EPSD	ICGC;COSMIC	5.604	Up-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q9Y520	PRRC2C	O14757	CHEK1	S1248	S1248C	1248	Missense	central	0	yes	7.198	0.000	EPSD	ICGC;COSMIC	5.604	Loss
CAMK_CAMKL_CHK1_CHEK1_ST	Q9Y520	PRRC2C	O14757	CHEK1	S2122	P2116L	2116	Missense	distal	-6	no	9.468	9.395	EPSD	ICGC	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q9Y520	PRRC2C	O14757	CHEK1	S2506	A2504S	2504	Missense	proximal	-2	no	6.287	6.173	EPSD	ICGC;COSMIC	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	O75151	PHF2	O14757	CHEK1	S86	P81L	81	Missense	distal	-5	no	1.666	6.373	EPSD	ICGC	5.604	Gain
CAMK_CAMKL_CHK1_CHEK1_ST	O75151	PHF2	O14757	CHEK1	T654	G657V	657	Missense	distal	3	no	6.116	6.542	EPSD	ICGC	5.604	Up-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	O75151	PHF2	O14757	CHEK1	T654	G657C	657	Missense	distal	3	no	6.116	5.254	EPSD	ICGC;COSMIC	5.604	Loss
CAMK_CAMKL_CHK1_CHEK1_ST	O75151	PHF2	O14757	CHEK1	T654	S647F	647	Missense	distal	-7	no	6.116	4.384	EPSD	ICGC;COSMIC	5.604	Loss
CAMK_CAMKL_CHK1_CHEK1_ST	P52272	HNRNPM	O14757	CHEK1	S86	L90P	90	Missense	distal	4	no	7.337	7.441	EPSD	ICGC	5.604	Up-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	P52272	HNRNPM	O14757	CHEK1	S86	E93K	93	Missense	distal	7	no	7.337	7.172	EPSD	ICGC;COSMIC	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	P52272	HNRNPM	O14757	CHEK1	S204	R201I	201	Missense	distal	-3	no	7.595	-1.163	EPSD	ICGC	5.604	Loss
CAMK_CAMKL_CHK1_CHEK1_ST	P52272	HNRNPM	O14757	CHEK1	S225	M226V	226	Missense	proximal	1	no	7.770	7.778	EPSD	ICGC;COSMIC	5.604	Up-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	P52272	HNRNPM	O14757	CHEK1	S225	V231F	231	Missense	distal	6	no	7.770	7.897	EPSD	ICGC	5.604	Up-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	P52272	HNRNPM	O14757	CHEK1	S365	R371L	371	Missense	distal	6	no	10.196	10.517	EPSD	ICGC	5.604	Up-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	P52272	HNRNPM	O14757	CHEK1	S432	M437I	437	Missense	distal	5	no	8.821	8.790	PhosphoSitePlus	ICGC	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	P52272	HNRNPM	O14757	CHEK1	S467	R471H	471	Missense	distal	4	no	6.839	7.000	EPSD	ICGC;COSMIC	5.604	Up-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	P52272	HNRNPM	O14757	CHEK1	S467	D463N	463	Missense	distal	-4	no	6.839	6.763	EPSD	ICGC;COSMIC;GDSC;CCLE	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	P52272	HNRNPM	O14757	CHEK1	S468	R471H	471	Missense	distal	3	no	6.452	6.483	EPSD	ICGC;COSMIC	5.604	Up-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	P52272	HNRNPM	O14757	CHEK1	S468	D463N	463	Missense	distal	-5	no	6.452	7.721	EPSD	ICGC;COSMIC;GDSC;CCLE	5.604	Up-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q15648	MED1	O14757	CHEK1	S18	L23H	23	Missense	distal	5	no	8.941	9.097	EPSD	ICGC;COSMIC	5.604	Up-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q15648	MED1	O14757	CHEK1	S256	S256L	256	Missense	central	0	yes	6.456	0.000	EPSD	ICGC;COSMIC	5.604	Loss
CAMK_CAMKL_CHK1_CHEK1_ST	Q15648	MED1	O14757	CHEK1	S387	R386Q	386	Missense	proximal	-1	no	6.340	6.355	EPSD	ICGC	5.604	Up-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q15648	MED1	O14757	CHEK1	S387	P383Q	383	Missense	distal	-4	no	6.340	6.572	EPSD	ICGC	5.604	Up-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q15648	MED1	O14757	CHEK1	S387	P381S	381	Missense	distal	-6	no	6.340	6.242	EPSD	ICGC	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q15648	MED1	O14757	CHEK1	S434	L437R	437	Missense	distal	3	no	6.500	6.932	EPSD	ICGC;COSMIC	5.604	Up-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q15648	MED1	O14757	CHEK1	S545	K538N	538	Missense	distal	-7	no	6.816	5.359	EPSD	ICGC;COSMIC	5.604	Loss
CAMK_CAMKL_CHK1_CHEK1_ST	Q15648	MED1	O14757	CHEK1	S588	F595S	595	Missense	distal	7	no	10.283	10.713	EPSD	ICGC;COSMIC	5.604	Up-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q15648	MED1	O14757	CHEK1	S671	P676S	676	Missense	distal	5	no	12.462	12.544	EPSD	ICGC;COSMIC	5.604	Up-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q15648	MED1	O14757	CHEK1	S671	P676L	676	Missense	distal	5	no	12.462	12.300	EPSD	ICGC;COSMIC	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q15648	MED1	O14757	CHEK1	T751	P748R	748	Missense	distal	-3	no	3.167	10.303	EPSD	ICGC	5.604	Gain
CAMK_CAMKL_CHK1_CHEK1_ST	Q15648	MED1	O14757	CHEK1	S771	Q764K	764	Missense	distal	-7	no	7.402	8.324	EPSD	ICGC;COSMIC	5.604	Up-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q15648	MED1	O14757	CHEK1	S1000	D1007H	1007	Missense	distal	7	no	10.031	9.439	EPSD	ICGC;COSMIC	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q15648	MED1	O14757	CHEK1	S1207	P1208Q	1208	Missense	proximal	1	no	5.984	6.055	EPSD	ICGC	5.604	Up-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q15648	MED1	O14757	CHEK1	S1296	S1302P	1302	Missense	distal	6	no	5.030	5.649	EPSD	ICGC;COSMIC	5.604	Gain
CAMK_CAMKL_CHK1_CHEK1_ST	Q15648	MED1	O14757	CHEK1	T1440	S1437R	1437	Missense	distal	-3	no	-0.589	9.107	EPSD	ICGC;COSMIC	5.604	Gain
CAMK_CAMKL_CHK1_CHEK1_ST	Q16204	CCDC6	O14757	CHEK1	T30	C27R	27	Missense	distal	-3	no	-1.410	6.681	EPSD	ICGC;COSMIC	5.604	Gain
CAMK_CAMKL_CHK1_CHEK1_ST	Q16204	CCDC6	O14757	CHEK1	S65	S65W	65	Missense	central	0	yes	12.699	0.000	EPSD	ICGC;COSMIC	5.604	Loss
CAMK_CAMKL_CHK1_CHEK1_ST	Q16204	CCDC6	O14757	CHEK1	S65	A64D	64	Missense	proximal	-1	no	12.699	12.495	EPSD	ICGC	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q16204	CCDC6	O14757	CHEK1	S65	R62S	62	Missense	distal	-3	no	12.699	3.003	EPSD	ICGC	5.604	Loss
CAMK_CAMKL_CHK1_CHEK1_ST	Q16204	CCDC6	O14757	CHEK1	S240	P238T	238	Missense	proximal	-2	no	6.503	6.473	EPSD;PhosphoSitePlus	ICGC	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q16204	CCDC6	O14757	CHEK1	S240	D236E	236	Missense	distal	-4	no	6.503	6.644	EPSD;PhosphoSitePlus	ICGC	5.604	Up-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q16204	CCDC6	O14757	CHEK1	S240	R246I	246	Missense	distal	6	no	6.503	6.458	EPSD;PhosphoSitePlus	ICGC;COSMIC;GDSC	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q16204	CCDC6	O14757	CHEK1	S240	V239I	239	Missense	proximal	-1	no	6.503	6.366	EPSD;PhosphoSitePlus	ICGC	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q16204	CCDC6	O14757	CHEK1	S244	P238T	238	Missense	distal	-6	no	5.651	5.623	PhosphoSitePlus;EPSD	ICGC	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q16204	CCDC6	O14757	CHEK1	S244	R246I	246	Missense	proximal	2	no	5.651	5.240	PhosphoSitePlus;EPSD	ICGC;COSMIC;GDSC	5.604	Loss
CAMK_CAMKL_CHK1_CHEK1_ST	Q16204	CCDC6	O14757	CHEK1	S244	V239I	239	Missense	distal	-5	no	5.651	7.097	PhosphoSitePlus;EPSD	ICGC	5.604	Up-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q16204	CCDC6	O14757	CHEK1	S249	R246I	246	Missense	distal	-3	no	9.198	0.440	EPSD	ICGC;COSMIC;GDSC	5.604	Loss
CAMK_CAMKL_CHK1_CHEK1_ST	Q16204	CCDC6	O14757	CHEK1	S249	P255T	255	Missense	distal	6	no	9.198	8.889	EPSD	ICGC;COSMIC	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q16204	CCDC6	O14757	CHEK1	S323	S327Y	327	Missense	distal	4	no	12.375	12.549	EPSD	ICGC	5.604	Up-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q16204	CCDC6	O14757	CHEK1	S323	L318F	318	Missense	distal	-5	no	12.375	8.811	EPSD	ICGC;COSMIC	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q16204	CCDC6	O14757	CHEK1	S351	R346I	346	Missense	distal	-5	no	5.883	6.828	EPSD	ICGC	5.604	Up-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q16204	CCDC6	O14757	CHEK1	S351	P358T	358	Missense	distal	7	no	5.883	5.761	EPSD	ICGC;COSMIC	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q16204	CCDC6	O14757	CHEK1	S351	P353T	353	Missense	proximal	2	no	5.883	5.568	EPSD	ICGC	5.604	Loss
CAMK_CAMKL_CHK1_CHEK1_ST	Q16204	CCDC6	O14757	CHEK1	S351	P347H	347	Missense	distal	-4	no	5.883	5.757	EPSD	ICGC	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q16204	CCDC6	O14757	CHEK1	S367	P368H	368	Missense	proximal	1	no	9.393	9.390	EPSD	ICGC;COSMIC	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q16204	CCDC6	O14757	CHEK1	S367	G369C	369	Missense	proximal	2	no	9.393	9.097	EPSD	ICGC;COSMIC	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q16204	CCDC6	O14757	CHEK1	S419	P420L	420	Missense	proximal	1	no	6.785	6.813	EPSD	ICGC	5.604	Up-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q16204	CCDC6	O14757	CHEK1	S419	R425P	425	Missense	distal	6	no	6.785	7.317	EPSD	ICGC	5.604	Up-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q9Y2T7	YBX2	O14757	CHEK1	S137	N130K	130	Missense	distal	-7	no	5.192	6.650	EPSD	ICGC	5.604	Gain
CAMK_CAMKL_CHK1_CHEK1_ST	Q9Y2T7	YBX2	O14757	CHEK1	S189	M195V	195	Missense	distal	6	no	12.256	12.132	EPSD	ICGC;COSMIC	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q9Y2T7	YBX2	O14757	CHEK1	S189	P185S	185	Missense	distal	-4	no	12.256	12.020	EPSD	ICGC	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q86WB0	ZC3HC1	O14757	CHEK1	T379	P377S	377	Missense	proximal	-2	no	9.170	8.886	EPSD	ICGC	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q86WB0	ZC3HC1	O14757	CHEK1	T379	S381T	381	Missense	proximal	2	no	9.170	8.778	EPSD	ICGC;COSMIC	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	P49790	NUP153	O14757	CHEK1	S297	A293D	293	Missense	distal	-4	no	8.363	8.354	PhosphoSitePlus;EPSD	ICGC;COSMIC	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	P49790	NUP153	O14757	CHEK1	S297	S300Y	300	Missense	distal	3	no	8.363	7.136	PhosphoSitePlus;EPSD	ICGC	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	P49790	NUP153	O14757	CHEK1	S297	Q295K	295	Missense	proximal	-2	no	8.363	8.136	PhosphoSitePlus;EPSD	ICGC	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	P49790	NUP153	O14757	CHEK1	S359	P362L	362	Missense	distal	3	no	6.536	5.772	EPSD	ICGC	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	P49790	NUP153	O14757	CHEK1	S359	Q365K	365	Missense	distal	6	no	6.536	6.455	EPSD	ICGC	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	P49790	NUP153	O14757	CHEK1	T369	P362L	362	Missense	distal	-7	no	7.453	7.238	EPSD	ICGC	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	P49790	NUP153	O14757	CHEK1	T369	Q365K	365	Missense	distal	-4	no	7.453	7.394	EPSD	ICGC	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	P49790	NUP153	O14757	CHEK1	T369	L367I	367	Missense	proximal	-2	no	7.453	7.476	EPSD	ICGC	5.604	Up-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	P49790	NUP153	O14757	CHEK1	T369	P372T	372	Missense	distal	3	no	7.453	6.980	EPSD	ICGC	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	P49790	NUP153	O14757	CHEK1	S374	L367I	367	Missense	distal	-7	no	6.002	6.243	EPSD	ICGC	5.604	Up-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	P49790	NUP153	O14757	CHEK1	S374	P372T	372	Missense	proximal	-2	no	6.002	5.972	EPSD	ICGC	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	P49790	NUP153	O14757	CHEK1	S405	N402K	402	Missense	distal	-3	no	-0.266	6.276	EPSD	ICGC;COSMIC	5.604	Gain
CAMK_CAMKL_CHK1_CHEK1_ST	P49790	NUP153	O14757	CHEK1	S607	A600E	600	Missense	distal	-7	no	7.698	7.472	EPSD	ICGC	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	P49790	NUP153	O14757	CHEK1	S624	S619L	619	Missense	distal	-5	no	3.434	6.622	EPSD	ICGC;COSMIC;GDSC;CCLE	5.604	Gain
CAMK_CAMKL_CHK1_CHEK1_ST	P49790	NUP153	O14757	CHEK1	S647	S644R	644	Missense	distal	-3	no	-1.451	8.245	EPSD	ICGC	5.604	Gain
CAMK_CAMKL_CHK1_CHEK1_ST	P49790	NUP153	O14757	CHEK1	S660	C667R	667	Missense	distal	7	no	5.790	6.195	EPSD	ICGC	5.604	Up-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	P49790	NUP153	O14757	CHEK1	S1019	A1020E	1020	Missense	proximal	1	no	9.747	9.829	EPSD	ICGC;COSMIC	5.604	Up-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	O15294	OGT	O14757	CHEK1	S11	V8M	8	Missense	distal	-3	no	3.278	6.592	EPSD	ICGC;COSMIC	5.604	Gain
CAMK_CAMKL_CHK1_CHEK1_ST	O15294	OGT	O14757	CHEK1	S20	R17C	17	Missense	distal	-3	no	11.636	3.544	PhosphoSitePlus	ICGC;COSMIC	5.604	Loss
CAMK_CAMKL_CHK1_CHEK1_ST	O15294	OGT	O14757	CHEK1	T819	T819A	819	Missense	central	0	yes	8.146	0.000	EPSD	ICGC;COSMIC	5.604	Loss
CAMK_CAMKL_CHK1_CHEK1_ST	O15294	OGT	O14757	CHEK1	T819	P824L	824	Missense	distal	5	no	8.146	7.984	EPSD	ICGC	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	O15294	OGT	O14757	CHEK1	S1004	P1005T	1005	Missense	proximal	1	no	12.665	12.710	EPSD	ICGC;COSMIC;GDSC;CCLE	5.604	Up-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q8NG66	NEK11	O14757	CHEK1	S273	P272L	272	Missense	proximal	-1	no	9.778	9.591	PhosphoSitePlus	ICGC;COSMIC	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q8NG66	NEK11	O14757	CHEK1	S273	I279V	279	Missense	distal	6	no	9.778	10.011	PhosphoSitePlus	ICGC	5.604	Up-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q8NG66	NEK11	O14757	CHEK1	S334	T340M	340	Missense	distal	6	no	9.919	10.010	EPSD	ICGC;COSMIC	5.604	Up-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q8NG66	NEK11	O14757	CHEK1	S334	Q337H	337	Missense	distal	3	no	9.919	8.888	EPSD	ICGC	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q8NG66	NEK11	O14757	CHEK1	S387	Q384R	384	Missense	distal	-3	no	1.366	8.573	EPSD	ICGC	5.604	Gain
CAMK_CAMKL_CHK1_CHEK1_ST	P10636	MAPT	O14757	CHEK1	S113	D116E	116	Missense	distal	3	no	5.761	5.664	EPSD	ICGC;COSMIC	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	P10636	MAPT	O14757	CHEK1	T167	P160L	160	Missense	distal	-7	no	7.796	7.581	EPSD	ICGC;COSMIC	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	P10636	MAPT	O14757	CHEK1	T167	R164T	164	Missense	distal	-3	no	7.796	-12.773	EPSD	ICGC;COSMIC	5.604	Loss
CAMK_CAMKL_CHK1_CHEK1_ST	P10636	MAPT	O14757	CHEK1	T167	A166T	166	Missense	proximal	-1	no	7.796	7.667	EPSD	ICGC	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	P10636	MAPT	O14757	CHEK1	S171	A166T	166	Missense	distal	-5	no	5.554	9.414	EPSD	ICGC	5.604	Gain
CAMK_CAMKL_CHK1_CHEK1_ST	P10636	MAPT	O14757	CHEK1	S214	G208C	208	Missense	distal	-6	no	12.525	12.523	EPSD	ICGC;COSMIC	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	P10636	MAPT	O14757	CHEK1	S214	R211S	211	Missense	distal	-3	no	12.525	2.829	EPSD	ICGC;COSMIC	5.604	Loss
CAMK_CAMKL_CHK1_CHEK1_ST	P10636	MAPT	O14757	CHEK1	S214	G213E	213	Missense	proximal	-1	no	12.525	12.418	EPSD	ICGC;COSMIC	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	P10636	MAPT	O14757	CHEK1	S341	T346I	346	Missense	distal	5	no	10.855	10.934	EPSD	ICGC;COSMIC	5.604	Up-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	P10636	MAPT	O14757	CHEK1	S341	A337V	337	Missense	distal	-4	no	10.855	10.776	EPSD	ICGC	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	P10636	MAPT	O14757	CHEK1	S341	D345E	345	Missense	distal	4	no	10.855	10.763	EPSD	ICGC;COSMIC	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	P10636	MAPT	O14757	CHEK1	S369	R364W	364	Missense	distal	-5	no	6.623	5.764	EPSD	ICGC;COSMIC	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	P10636	MAPT	O14757	CHEK1	S369	P363L	363	Missense	distal	-6	no	6.623	6.549	EPSD	ICGC	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q14676	MDC1	O14757	CHEK1	S112	P109S	109	Missense	distal	-3	no	7.587	5.028	EPSD	ICGC;GDSC;CCLE	5.604	Loss
CAMK_CAMKL_CHK1_CHEK1_ST	Q14676	MDC1	O14757	CHEK1	S112	R114C	114	Missense	proximal	2	no	7.587	7.321	EPSD	ICGC;COSMIC	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q14676	MDC1	O14757	CHEK1	S112	Q118K	118	Missense	distal	6	no	7.587	7.506	EPSD	ICGC;COSMIC	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q14676	MDC1	O14757	CHEK1	S168	E170A	170	Missense	proximal	2	no	6.964	6.871	EPSD	ICGC;COSMIC	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q14676	MDC1	O14757	CHEK1	S168	V172I	172	Missense	distal	4	no	6.964	6.904	EPSD	ICGC;COSMIC	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q14676	MDC1	O14757	CHEK1	T447	D452G	452	Missense	distal	5	no	12.033	11.754	EPSD	ICGC	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q14676	MDC1	O14757	CHEK1	T447	S445R	445	Missense	proximal	-2	no	12.033	12.132	EPSD	ICGC;COSMIC	5.604	Up-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q14676	MDC1	O14757	CHEK1	T448	S445R	445	Missense	distal	-3	no	-1.567	8.129	EPSD	ICGC;COSMIC	5.604	Gain
CAMK_CAMKL_CHK1_CHEK1_ST	Q14676	MDC1	O14757	CHEK1	S453	D452G	452	Missense	proximal	-1	no	6.224	6.273	EPSD	ICGC	5.604	Up-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q14676	MDC1	O14757	CHEK1	S453	D456V	456	Missense	distal	3	no	6.224	5.005	EPSD	ICGC;COSMIC	5.604	Loss
CAMK_CAMKL_CHK1_CHEK1_ST	Q14676	MDC1	O14757	CHEK1	S874	D868N	868	Missense	distal	-6	no	7.950	8.164	EPSD	ICGC;COSMIC	5.604	Up-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q14676	MDC1	O14757	CHEK1	S981	G987R	987	Missense	distal	6	no	5.787	5.662	EPSD	ICGC;COSMIC	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q14676	MDC1	O14757	CHEK1	S981	P977L	977	Missense	distal	-4	no	5.787	5.603	EPSD	ICGC	5.604	Loss
CAMK_CAMKL_CHK1_CHEK1_ST	Q14676	MDC1	O14757	CHEK1	S981	P977S	977	Missense	distal	-4	no	5.787	5.551	EPSD	ICGC	5.604	Loss
CAMK_CAMKL_CHK1_CHEK1_ST	Q14676	MDC1	O14757	CHEK1	S990	G987R	987	Missense	distal	-3	no	-0.398	7.376	EPSD	ICGC;COSMIC	5.604	Gain
CAMK_CAMKL_CHK1_CHEK1_ST	Q14676	MDC1	O14757	CHEK1	T1295	R1292Q	1292	Missense	distal	-3	no	8.594	1.387	EPSD	ICGC;COSMIC	5.604	Loss
CAMK_CAMKL_CHK1_CHEK1_ST	Q14676	MDC1	O14757	CHEK1	S1658	P1655R	1655	Missense	distal	-3	no	4.116	11.252	EPSD	ICGC;COSMIC	5.604	Gain
CAMK_CAMKL_CHK1_CHEK1_ST	Q14676	MDC1	O14757	CHEK1	S1814	L1815I	1815	Missense	proximal	1	no	8.693	8.666	EPSD	ICGC	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q14676	MDC1	O14757	CHEK1	S1814	M1818T	1818	Missense	distal	4	no	8.693	8.594	EPSD	ICGC;COSMIC	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q14676	MDC1	O14757	CHEK1	S1878	R1883P	1883	Missense	distal	5	no	7.677	7.698	EPSD	ICGC	5.604	Up-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	P52292	KPNA2	O14757	CHEK1	T25	R29L	29	Missense	distal	4	no	6.135	6.121	EPSD	ICGC	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	P52292	KPNA2	O14757	CHEK1	S54	N52I	52	Missense	proximal	-2	no	11.941	11.880	PhosphoSitePlus	ICGC;COSMIC	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	O95707	POP4	O14757	CHEK1	S10	Y6N	6	Missense	distal	-4	no	6.269	6.740	PhosphoSitePlus	ICGC	5.604	Up-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	O95707	POP4	O14757	CHEK1	S10	L9F	9	Missense	proximal	-1	no	6.269	6.283	PhosphoSitePlus	ICGC;COSMIC	5.604	Up-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	O95707	POP4	O14757	CHEK1	S17	V19A	19	Missense	proximal	2	no	6.378	6.941	EPSD	ICGC	5.604	Up-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	P35612	ADD2	O14757	CHEK1	S11	G17W	17	Missense	distal	6	no	5.436	5.778	EPSD	ICGC;COSMIC	5.604	Gain
CAMK_CAMKL_CHK1_CHEK1_ST	P35612	ADD2	O14757	CHEK1	T55	L58Q	58	Missense	distal	3	no	4.970	6.464	EPSD	ICGC;COSMIC	5.604	Gain
CAMK_CAMKL_CHK1_CHEK1_ST	P35612	ADD2	O14757	CHEK1	S62	E65Q	65	Missense	distal	3	no	6.159	5.759	EPSD	ICGC;COSMIC	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	P35612	ADD2	O14757	CHEK1	S62	E66K	66	Missense	distal	4	no	6.159	6.153	EPSD	ICGC	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	P35612	ADD2	O14757	CHEK1	S62	M56V	56	Missense	distal	-6	no	6.159	6.109	EPSD	ICGC;COSMIC	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	P35612	ADD2	O14757	CHEK1	S62	L58Q	58	Missense	distal	-4	no	6.159	6.575	EPSD	ICGC;COSMIC	5.604	Up-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	P35612	ADD2	O14757	CHEK1	S396	E390Q	390	Missense	distal	-6	no	10.020	10.144	EPSD	ICGC;COSMIC	5.604	Up-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	P35612	ADD2	O14757	CHEK1	S396	H394P	394	Missense	proximal	-2	no	10.020	10.141	EPSD	ICGC;COSMIC	5.604	Up-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	P35612	ADD2	O14757	CHEK1	S455	S452R	452	Missense	distal	-3	no	2.092	11.788	EPSD	ICGC	5.604	Gain
CAMK_CAMKL_CHK1_CHEK1_ST	P35612	ADD2	O14757	CHEK1	S532	R529Q	529	Missense	distal	-3	no	10.836	3.629	EPSD	ICGC;COSMIC	5.604	Loss
CAMK_CAMKL_CHK1_CHEK1_ST	P35612	ADD2	O14757	CHEK1	S617	P614R	614	Missense	distal	-3	no	0.609	7.746	EPSD	ICGC	5.604	Gain
CAMK_CAMKL_CHK1_CHEK1_ST	P35612	ADD2	O14757	CHEK1	S667	M669I	669	Missense	proximal	2	no	6.906	6.327	EPSD	ICGC	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	P35612	ADD2	O14757	CHEK1	S667	S663R	663	Missense	distal	-4	no	6.906	7.214	EPSD	ICGC	5.604	Up-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	P35612	ADD2	O14757	CHEK1	S667	D674E	674	Missense	distal	7	no	6.906	6.849	EPSD	ICGC	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	P35612	ADD2	O14757	CHEK1	T671	M669I	669	Missense	proximal	-2	no	6.141	6.127	EPSD	ICGC	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	P35612	ADD2	O14757	CHEK1	T671	D674E	674	Missense	distal	3	no	6.141	6.044	EPSD	ICGC	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	P35612	ADD2	O14757	CHEK1	T711	S718I	718	Missense	distal	7	no	6.300	6.008	EPSD	ICGC;CCLE	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	P35612	ADD2	O14757	CHEK1	S713	S718I	718	Missense	distal	5	no	8.097	7.954	PhosphoSitePlus	ICGC;CCLE	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	P35611	ADD1	O14757	CHEK1	S59	A66S	66	Missense	distal	7	no	5.981	5.932	EPSD	ICGC	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	P35611	ADD1	O14757	CHEK1	S59	M52I	52	Missense	distal	-7	no	5.981	5.739	EPSD	ICGC	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	P35611	ADD1	O14757	CHEK1	S59	V58A	58	Missense	proximal	-1	no	5.981	6.059	EPSD	ICGC;COSMIC	5.604	Up-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	P35611	ADD1	O14757	CHEK1	S59	M60K	60	Missense	proximal	1	no	5.981	6.021	EPSD	ICGC;COSMIC	5.604	Up-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	P35611	ADD1	O14757	CHEK1	S135	S133F	133	Missense	proximal	-2	no	5.380	5.670	EPSD	ICGC	5.604	Gain
CAMK_CAMKL_CHK1_CHEK1_ST	P35611	ADD1	O14757	CHEK1	S353	P359L	359	Missense	distal	6	no	6.163	5.953	EPSD	ICGC;COSMIC	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	P35611	ADD1	O14757	CHEK1	S353	G357V	357	Missense	distal	4	no	6.163	6.207	EPSD	ICGC	5.604	Up-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	P35611	ADD1	O14757	CHEK1	S353	P359T	359	Missense	distal	6	no	6.163	5.855	EPSD	ICGC;COSMIC	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	P35611	ADD1	O14757	CHEK1	S355	P359L	359	Missense	distal	4	no	7.969	7.865	EPSD	ICGC;COSMIC	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	P35611	ADD1	O14757	CHEK1	S355	G357V	357	Missense	proximal	2	no	7.969	7.927	EPSD	ICGC	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	P35611	ADD1	O14757	CHEK1	S355	P359T	359	Missense	distal	4	no	7.969	7.840	EPSD	ICGC;COSMIC	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	P35611	ADD1	O14757	CHEK1	T364	P359L	359	Missense	distal	-5	no	1.445	6.151	EPSD	ICGC;COSMIC	5.604	Gain
CAMK_CAMKL_CHK1_CHEK1_ST	P35611	ADD1	O14757	CHEK1	S408	K403T	403	Missense	distal	-5	no	8.571	8.316	EPSD	ICGC	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	P35611	ADD1	O14757	CHEK1	S408	S408I	408	Missense	central	0	yes	8.571	0.000	EPSD	ICGC;COSMIC	5.604	Loss
CAMK_CAMKL_CHK1_CHEK1_ST	P35611	ADD1	O14757	CHEK1	T470	D476N	476	Missense	distal	6	no	5.527	5.845	EPSD	ICGC;COSMIC	5.604	Gain
CAMK_CAMKL_CHK1_CHEK1_ST	P35611	ADD1	O14757	CHEK1	T482	D476N	476	Missense	distal	-6	no	8.115	8.328	EPSD	ICGC;COSMIC	5.604	Up-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	P35611	ADD1	O14757	CHEK1	S645	S650L	650	Missense	distal	5	no	5.682	5.438	EPSD	ICGC;COSMIC	5.604	Loss
CAMK_CAMKL_CHK1_CHEK1_ST	P35611	ADD1	O14757	CHEK1	S669	P667H	667	Missense	proximal	-2	no	6.914	6.793	EPSD	ICGC;COSMIC	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	P35611	ADD1	O14757	CHEK1	S726	R723C	723	Missense	distal	-3	no	11.735	3.644	PhosphoSitePlus	ICGC;COSMIC	5.604	Loss
CAMK_CAMKL_CHK1_CHEK1_ST	P35611	ADD1	O14757	CHEK1	S726	P725L	725	Missense	proximal	-1	no	11.735	11.549	PhosphoSitePlus	ICGC;COSMIC	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q6UB98	ANKRD12	O14757	CHEK1	S526	G519W	519	Missense	distal	-7	no	7.615	6.031	EPSD	ICGC;COSMIC	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q6UB98	ANKRD12	O14757	CHEK1	T540	H537R	537	Missense	distal	-3	no	4.171	9.980	EPSD	ICGC;COSMIC	5.604	Gain
CAMK_CAMKL_CHK1_CHEK1_ST	Q6UB98	ANKRD12	O14757	CHEK1	S903	K896N	896	Missense	distal	-7	no	7.850	6.392	EPSD	ICGC	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q6UB98	ANKRD12	O14757	CHEK1	S903	K906R	906	Missense	distal	3	no	7.850	7.203	EPSD	ICGC;COSMIC	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q6UB98	ANKRD12	O14757	CHEK1	S903	K896R	896	Missense	distal	-7	no	7.850	6.670	EPSD	ICGC	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q6UB98	ANKRD12	O14757	CHEK1	S903	K906N	906	Missense	distal	3	no	7.850	8.047	EPSD	ICGC	5.604	Up-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q6UB98	ANKRD12	O14757	CHEK1	S1056	T1063A	1063	Missense	distal	7	no	6.113	6.229	EPSD	ICGC	5.604	Up-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q6UB98	ANKRD12	O14757	CHEK1	S1085	L1086F	1086	Missense	proximal	1	no	8.603	8.608	EPSD	ICGC;COSMIC	5.604	Up-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q6UB98	ANKRD12	O14757	CHEK1	S1143	E1137G	1137	Missense	distal	-6	no	14.270	14.430	EPSD	ICGC;COSMIC	5.604	Up-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q6UB98	ANKRD12	O14757	CHEK1	S1166	V1172L	1172	Missense	distal	6	no	8.505	8.638	EPSD	ICGC	5.604	Up-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q6UB98	ANKRD12	O14757	CHEK1	S1290	E1292K	1292	Missense	proximal	2	no	7.393	7.435	EPSD	ICGC;COSMIC	5.604	Up-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q6UB98	ANKRD12	O14757	CHEK1	S1311	C1310F	1310	Missense	proximal	-1	no	6.033	6.111	EPSD	ICGC	5.604	Up-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q6UB98	ANKRD12	O14757	CHEK1	S1790	R1791L	1791	Missense	proximal	1	no	9.650	9.615	EPSD	ICGC	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q6UB98	ANKRD12	O14757	CHEK1	S1790	R1785W	1785	Missense	distal	-5	no	9.650	8.791	EPSD	ICGC;COSMIC	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q9H8N7	ZNF395	O14757	CHEK1	S66	T67N	67	Missense	proximal	1	no	6.704	6.694	EPSD	ICGC	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q9H8N7	ZNF395	O14757	CHEK1	S66	A64D	64	Missense	proximal	-2	no	6.704	6.637	EPSD	ICGC	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q9H8N7	ZNF395	O14757	CHEK1	S275	R270Q	270	Missense	distal	-5	no	8.740	8.344	EPSD	ICGC;COSMIC	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q9H8N7	ZNF395	O14757	CHEK1	S275	K281R	281	Missense	distal	6	no	8.740	8.828	EPSD	ICGC;COSMIC	5.604	Up-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q9H8N7	ZNF395	O14757	CHEK1	S376	P370T	370	Missense	distal	-6	no	7.777	7.749	EPSD	ICGC	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q9H8N7	ZNF395	O14757	CHEK1	S376	P382T	382	Missense	distal	6	no	7.777	7.469	EPSD	ICGC	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q9H8N7	ZNF395	O14757	CHEK1	S447	R444W	444	Missense	distal	-3	no	8.186	-25.417	PhosphoSitePlus	ICGC;COSMIC;GDSC;CCLE	5.604	Loss
CAMK_CAMKL_CHK1_CHEK1_ST	Q9H8N7	ZNF395	O14757	CHEK1	S447	S441Y	441	Missense	distal	-6	no	8.186	8.348	PhosphoSitePlus	ICGC;COSMIC	5.604	Up-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q9H8N7	ZNF395	O14757	CHEK1	S449	R444W	444	Missense	distal	-5	no	10.362	9.504	EPSD	ICGC;COSMIC;GDSC;CCLE	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q9H8N7	ZNF395	O14757	CHEK1	S474	R471Q	471	Missense	distal	-3	no	8.825	1.618	EPSD	ICGC;COSMIC	5.604	Loss
CAMK_CAMKL_CHK1_CHEK1_ST	Q9H8N7	ZNF395	O14757	CHEK1	S474	A476V	476	Missense	proximal	2	no	8.825	8.262	EPSD	ICGC;COSMIC	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q9H8N7	ZNF395	O14757	CHEK1	S474	R480G	480	Missense	distal	6	no	8.825	8.950	EPSD	ICGC;COSMIC	5.604	Up-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	P12956	XRCC6	O14757	CHEK1	T170	R165S	165	Missense	distal	-5	no	8.495	8.284	EPSD	ICGC	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	P12956	XRCC6	O14757	CHEK1	T170	G177V	177	Missense	distal	7	no	8.495	8.525	EPSD	ICGC	5.604	Up-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	P12956	XRCC6	O14757	CHEK1	T170	I166T	166	Missense	distal	-4	no	8.495	8.424	EPSD	ICGC;COSMIC	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	P12956	XRCC6	O14757	CHEK1	T334	R339L	339	Missense	distal	5	no	6.400	6.259	EPSD	ICGC	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	P12956	XRCC6	O14757	CHEK1	T334	R339W	339	Missense	distal	5	no	6.400	6.232	EPSD	ICGC;COSMIC	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	P12956	XRCC6	O14757	CHEK1	S477	E479D	479	Missense	proximal	2	no	12.198	12.116	PhosphoSitePlus	ICGC	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	P12956	XRCC6	O14757	CHEK1	S520	R517K	517	Missense	distal	-3	no	11.067	7.242	EPSD	ICGC;COSMIC	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q13257	MAD2L1	O14757	CHEK1	S185	L183R	183	Missense	proximal	-2	no	7.770	7.764	PhosphoSitePlus;EPSD	ICGC;COSMIC	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q13257	MAD2L1	O14757	CHEK1	S185	R182C	182	Missense	distal	-3	no	7.770	-0.321	PhosphoSitePlus;EPSD	ICGC;COSMIC	5.604	Loss
CAMK_CAMKL_CHK1_CHEK1_ST	Q13257	MAD2L1	O14757	CHEK1	T187	L183R	183	Missense	distal	-4	no	6.561	6.817	EPSD;PhosphoSitePlus	ICGC;COSMIC	5.604	Up-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q13257	MAD2L1	O14757	CHEK1	T187	R182C	182	Missense	distal	-5	no	6.561	5.883	EPSD;PhosphoSitePlus	ICGC;COSMIC	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q13257	MAD2L1	O14757	CHEK1	S195	A198D	198	Missense	distal	3	no	5.145	6.609	EPSD	ICGC	5.604	Gain
CAMK_CAMKL_CHK1_CHEK1_ST	Q13043	STK4	O14757	CHEK1	T120	T122A	122	Missense	proximal	2	no	8.540	9.388	EPSD	ICGC;COSMIC	5.604	Up-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q13043	STK4	O14757	CHEK1	T122	T122A	122	Missense	central	0	yes	6.461	0.000	EPSD	ICGC;COSMIC	5.604	Loss
CAMK_CAMKL_CHK1_CHEK1_ST	Q13043	STK4	O14757	CHEK1	S307	Q309E	309	Missense	proximal	2	no	12.367	12.482	EPSD	ICGC;COSMIC	5.604	Up-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q13043	STK4	O14757	CHEK1	T387	K382N	382	Missense	distal	-5	no	8.578	7.685	EPSD	ICGC;COSMIC	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	O75592	MYCBP2	O14757	CHEK1	S861	R858Q	858	Missense	distal	-3	no	12.192	4.985	EPSD	ICGC	5.604	Loss
CAMK_CAMKL_CHK1_CHEK1_ST	O75592	MYCBP2	O14757	CHEK1	S2353	A2352S	2352	Missense	proximal	-1	no	6.610	6.277	EPSD	ICGC	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	O75592	MYCBP2	O14757	CHEK1	S2353	S2353P	2353	Missense	central	0	yes	6.610	0.000	EPSD	ICGC	5.604	Loss
CAMK_CAMKL_CHK1_CHEK1_ST	O75592	MYCBP2	O14757	CHEK1	T2355	A2352S	2352	Missense	distal	-3	no	6.273	3.289	EPSD	ICGC	5.604	Loss
CAMK_CAMKL_CHK1_CHEK1_ST	O75592	MYCBP2	O14757	CHEK1	T2355	S2353P	2353	Missense	proximal	-2	no	6.273	6.557	EPSD	ICGC	5.604	Up-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	O75592	MYCBP2	O14757	CHEK1	S2445	Q2450K	2450	Missense	distal	5	no	8.657	8.705	EPSD	ICGC	5.604	Up-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	O75592	MYCBP2	O14757	CHEK1	S2445	H2446Q	2446	Missense	proximal	1	no	8.657	8.731	EPSD	ICGC	5.604	Up-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	O75592	MYCBP2	O14757	CHEK1	S2445	L2449I	2449	Missense	distal	4	no	8.657	8.672	EPSD	ICGC;COSMIC	5.604	Up-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	O75592	MYCBP2	O14757	CHEK1	S2445	R2444S	2444	Missense	proximal	-1	no	8.657	8.496	EPSD	ICGC;COSMIC	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	O75592	MYCBP2	O14757	CHEK1	S3084	K3087N	3087	Missense	distal	3	no	6.362	6.559	EPSD	ICGC;COSMIC	5.604	Up-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	O75592	MYCBP2	O14757	CHEK1	S3084	I3077V	3077	Missense	distal	-7	no	6.362	6.798	EPSD	ICGC;COSMIC	5.604	Up-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	O75592	MYCBP2	O14757	CHEK1	S3084	P3090H	3090	Missense	distal	6	no	6.362	6.118	EPSD	ICGC	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	O75592	MYCBP2	O14757	CHEK1	S3388	P3392L	3392	Missense	distal	4	no	6.107	6.003	EPSD	ICGC	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	O75592	MYCBP2	O14757	CHEK1	S3388	T3387K	3387	Missense	proximal	-1	no	6.107	5.915	EPSD	ICGC	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q9BRD0	BUD13	O14757	CHEK1	S18	E11K	11	Missense	distal	-7	no	17.342	18.039	PhosphoSitePlus	ICGC	5.604	Up-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q9BRD0	BUD13	O14757	CHEK1	S18	D25E	25	Missense	distal	7	no	17.342	17.284	PhosphoSitePlus	ICGC	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q9BRD0	BUD13	O14757	CHEK1	S18	E11D	11	Missense	distal	-7	no	17.342	16.889	PhosphoSitePlus	ICGC	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q9BRD0	BUD13	O14757	CHEK1	T135	P138S	138	Missense	distal	3	no	9.017	8.687	EPSD	ICGC	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q9BRD0	BUD13	O14757	CHEK1	T147	D143E	143	Missense	distal	-4	no	10.525	10.666	EPSD	ICGC	5.604	Up-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q9BRD0	BUD13	O14757	CHEK1	T147	P148T	148	Missense	proximal	1	no	10.525	10.569	EPSD	ICGC	5.604	Up-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q9BRD0	BUD13	O14757	CHEK1	T159	P164L	164	Missense	distal	5	no	8.933	8.772	EPSD	ICGC	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q9BRD0	BUD13	O14757	CHEK1	T159	P160S	160	Missense	proximal	1	no	8.933	8.970	EPSD	ICGC	5.604	Up-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q9BRD0	BUD13	O14757	CHEK1	S172	P176L	176	Missense	distal	4	no	7.652	7.548	EPSD	ICGC;COSMIC	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q9BRD0	BUD13	O14757	CHEK1	S184	R181H	181	Missense	distal	-3	no	11.487	5.678	EPSD	ICGC;COSMIC	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q9BRD0	BUD13	O14757	CHEK1	S197	R194C	194	Missense	distal	-3	no	11.188	3.096	EPSD	ICGC;COSMIC	5.604	Loss
CAMK_CAMKL_CHK1_CHEK1_ST	Q9BRD0	BUD13	O14757	CHEK1	S197	D196V	196	Missense	proximal	-1	no	11.188	11.314	EPSD	ICGC;COSMIC	5.604	Up-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q9BRD0	BUD13	O14757	CHEK1	S222	R217K	217	Missense	distal	-5	no	11.661	12.837	EPSD	ICGC;COSMIC	5.604	Up-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q9BRD0	BUD13	O14757	CHEK1	S222	P225L	225	Missense	distal	3	no	11.661	10.897	EPSD	ICGC;COSMIC	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q9BRD0	BUD13	O14757	CHEK1	S222	P225S	225	Missense	distal	3	no	11.661	11.332	EPSD	ICGC;COSMIC	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q9BRD0	BUD13	O14757	CHEK1	S235	R232S	232	Missense	distal	-3	no	9.590	-0.106	EPSD	ICGC;COSMIC	5.604	Loss
CAMK_CAMKL_CHK1_CHEK1_ST	Q9BRD0	BUD13	O14757	CHEK1	S248	T251K	251	Missense	distal	3	no	4.830	5.617	EPSD	ICGC;CCLE	5.604	Gain
CAMK_CAMKL_CHK1_CHEK1_ST	Q9BRD0	BUD13	O14757	CHEK1	S271	A267D	267	Missense	distal	-4	no	7.796	7.787	EPSD	ICGC	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q9BRD0	BUD13	O14757	CHEK1	S271	S271P	271	Missense	central	0	yes	7.796	0.000	EPSD	ICGC;COSMIC	5.604	Loss
CAMK_CAMKL_CHK1_CHEK1_ST	Q9BRD0	BUD13	O14757	CHEK1	S296	K303N	303	Missense	distal	7	no	9.392	9.453	EPSD	ICGC	5.604	Up-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q9BRD0	BUD13	O14757	CHEK1	S296	P300T	300	Missense	distal	4	no	9.392	9.263	EPSD	ICGC;COSMIC	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	O60343	TBC1D4	O14757	CHEK1	S66	R63H	63	Missense	distal	-3	no	9.780	3.971	EPSD	ICGC;COSMIC	5.604	Loss
CAMK_CAMKL_CHK1_CHEK1_ST	O60343	TBC1D4	O14757	CHEK1	S66	A60T	60	Missense	distal	-6	no	9.780	9.976	EPSD	ICGC	5.604	Up-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	O60343	TBC1D4	O14757	CHEK1	S66	S66N	66	Missense	central	0	yes	9.780	0.000	EPSD	ICGC;COSMIC	5.604	Loss
CAMK_CAMKL_CHK1_CHEK1_ST	O60343	TBC1D4	O14757	CHEK1	S341	A340T	340	Missense	proximal	-1	no	7.708	7.579	EPSD	ICGC;COSMIC	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	O60343	TBC1D4	O14757	CHEK1	S341	Q347E	347	Missense	distal	6	no	7.708	7.357	EPSD	ICGC;COSMIC	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	O60343	TBC1D4	O14757	CHEK1	S341	P335S	335	Missense	distal	-6	no	7.708	7.610	EPSD	ICGC	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	O60343	TBC1D4	O14757	CHEK1	S341	A340V	340	Missense	proximal	-1	no	7.708	7.630	EPSD	ICGC;COSMIC	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	O60343	TBC1D4	O14757	CHEK1	S588	L586I	586	Missense	proximal	-2	no	11.594	11.617	PhosphoSitePlus;EPSD	ICGC	5.604	Up-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	O60343	TBC1D4	O14757	CHEK1	S588	R585Q	585	Missense	distal	-3	no	11.594	4.387	PhosphoSitePlus;EPSD	ICGC	5.604	Loss
CAMK_CAMKL_CHK1_CHEK1_ST	O60343	TBC1D4	O14757	CHEK1	S588	R585G	585	Missense	distal	-3	no	11.594	3.820	PhosphoSitePlus;EPSD	ICGC	5.604	Loss
CAMK_CAMKL_CHK1_CHEK1_ST	O60343	TBC1D4	O14757	CHEK1	S597	L598I	598	Missense	proximal	1	no	9.239	9.213	EPSD	ICGC;COSMIC	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	O60343	TBC1D4	O14757	CHEK1	S597	N596K	596	Missense	proximal	-1	no	9.239	9.034	EPSD	ICGC	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	O60343	TBC1D4	O14757	CHEK1	S605	L598I	598	Missense	distal	-7	no	7.953	8.195	EPSD	ICGC;COSMIC	5.604	Up-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	O60343	TBC1D4	O14757	CHEK1	S605	P606T	606	Missense	proximal	1	no	7.953	7.998	EPSD	ICGC	5.604	Up-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	O60343	TBC1D4	O14757	CHEK1	S605	G607W	607	Missense	proximal	2	no	7.953	7.749	EPSD	ICGC;COSMIC	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	O60343	TBC1D4	O14757	CHEK1	T642	Q635K	635	Missense	distal	-7	no	8.825	9.747	EPSD	ICGC	5.604	Up-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	O60343	TBC1D4	O14757	CHEK1	T642	P646Q	646	Missense	distal	4	no	8.825	8.735	EPSD	ICGC;COSMIC	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	P36507	MAP2K2	O14757	CHEK1	T59	Q60P	60	Missense	proximal	1	no	7.692	7.621	PhosphoSitePlus	ICGC;COSMIC;GDSC;CCLE	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	P36507	MAP2K2	O14757	CHEK1	T59	K61E	61	Missense	proximal	2	no	7.692	7.650	PhosphoSitePlus	ICGC	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	P36507	MAP2K2	O14757	CHEK1	S306	P300L	300	Missense	distal	-6	no	8.439	8.366	EPSD	ICGC;COSMIC	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	P36507	MAP2K2	O14757	CHEK1	S306	G307C	307	Missense	proximal	1	no	8.439	8.438	EPSD	ICGC;COSMIC	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	P36507	MAP2K2	O14757	CHEK1	S306	M310I	310	Missense	distal	4	no	8.439	8.380	EPSD	ICGC;COSMIC	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q9GZR7	DDX24	O14757	CHEK1	S208	P202Q	202	Missense	distal	-6	no	8.739	8.643	EPSD	ICGC;COSMIC	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q9GZR7	DDX24	O14757	CHEK1	S797	F801L	801	Missense	distal	4	no	7.379	7.317	EPSD	ICGC	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q14247	CTTN	O14757	CHEK1	S113	V115L	115	Missense	proximal	2	no	11.869	11.581	EPSD	ICGC	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q14247	CTTN	O14757	CHEK1	S113	G120C	120	Missense	distal	7	no	11.869	11.458	EPSD	ICGC	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q14247	CTTN	O14757	CHEK1	S113	Q114H	114	Missense	proximal	1	no	11.869	11.795	EPSD	ICGC	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q14247	CTTN	O14757	CHEK1	S150	K144N	144	Missense	distal	-6	no	10.762	10.894	EPSD	ICGC	5.604	Up-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q14247	CTTN	O14757	CHEK1	S155	G160S	160	Missense	distal	5	no	6.590	6.781	EPSD	ICGC;COSMIC	5.604	Up-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q14247	CTTN	O14757	CHEK1	S187	G180V	180	Missense	distal	-7	no	9.171	9.186	EPSD	ICGC;COSMIC	5.604	Up-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q14247	CTTN	O14757	CHEK1	S187	S187P	187	Missense	central	0	yes	9.171	0.000	EPSD	ICGC	5.604	Loss
CAMK_CAMKL_CHK1_CHEK1_ST	Q14247	CTTN	O14757	CHEK1	S192	G196D	196	Missense	distal	4	no	9.783	9.766	EPSD	ICGC;COSMIC	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q14247	CTTN	O14757	CHEK1	S192	S187P	187	Missense	distal	-5	no	9.783	8.264	EPSD	ICGC	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q14247	CTTN	O14757	CHEK1	S192	G197D	197	Missense	distal	5	no	9.783	10.061	EPSD	ICGC;COSMIC	5.604	Up-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q14247	CTTN	O14757	CHEK1	S224	G231R	231	Missense	distal	7	no	8.271	8.266	EPSD	ICGC	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q14247	CTTN	O14757	CHEK1	S282	D288N	288	Missense	distal	6	no	8.959	9.277	EPSD	ICGC;COSMIC	5.604	Up-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q14247	CTTN	O14757	CHEK1	S282	A283V	283	Missense	proximal	1	no	8.959	8.935	EPSD	ICGC;COSMIC	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q14247	CTTN	O14757	CHEK1	S282	D288H	288	Missense	distal	6	no	8.959	9.518	EPSD	ICGC;COSMIC	5.604	Up-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q14247	CTTN	O14757	CHEK1	S282	V275F	275	Missense	distal	-7	no	8.959	7.433	EPSD	ICGC;COSMIC	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q14247	CTTN	O14757	CHEK1	S282	S282F	282	Missense	central	0	yes	8.959	0.000	EPSD	ICGC	5.604	Loss
CAMK_CAMKL_CHK1_CHEK1_ST	Q14247	CTTN	O14757	CHEK1	S282	E278D	278	Missense	distal	-4	no	8.959	8.818	EPSD	ICGC	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q14247	CTTN	O14757	CHEK1	S298	G305V	305	Missense	distal	7	no	12.645	12.675	PhosphoSitePlus	ICGC	5.604	Up-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q14247	CTTN	O14757	CHEK1	T399	T401M	401	Missense	proximal	2	no	6.087	6.552	EPSD	ICGC;COSMIC	5.604	Up-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q14247	CTTN	O14757	CHEK1	T399	T401A	401	Missense	proximal	2	no	6.087	6.935	EPSD	ICGC	5.604	Up-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q14247	CTTN	O14757	CHEK1	T399	S405L	405	Missense	distal	6	no	6.087	6.496	EPSD	ICGC;COSMIC;GDSC	5.604	Up-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q14247	CTTN	O14757	CHEK1	S405	E412K	412	Missense	distal	7	no	5.971	5.805	EPSD	ICGC;COSMIC	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q14247	CTTN	O14757	CHEK1	S405	T401M	401	Missense	distal	-4	no	5.971	6.167	EPSD	ICGC;COSMIC	5.604	Up-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q14247	CTTN	O14757	CHEK1	S405	T401A	401	Missense	distal	-4	no	5.971	6.401	EPSD	ICGC	5.604	Up-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q14247	CTTN	O14757	CHEK1	S405	S405L	405	Missense	central	0	yes	5.971	0.000	EPSD	ICGC;COSMIC;GDSC	5.604	Loss
CAMK_CAMKL_CHK1_CHEK1_ST	Q14247	CTTN	O14757	CHEK1	S405	A407T	407	Missense	proximal	2	no	5.971	5.123	EPSD	ICGC;COSMIC	5.604	Loss
CAMK_CAMKL_CHK1_CHEK1_ST	Q14247	CTTN	O14757	CHEK1	S417	E412K	412	Missense	distal	-5	no	7.084	9.646	EPSD	ICGC;COSMIC	5.604	Up-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q14247	CTTN	O14757	CHEK1	S417	L415P	415	Missense	proximal	-2	no	7.084	7.263	EPSD	ICGC	5.604	Up-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q14247	CTTN	O14757	CHEK1	S417	A424V	424	Missense	distal	7	no	7.084	7.164	EPSD	ICGC;COSMIC;GDSC	5.604	Up-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	P39748	FEN1	O14757	CHEK1	S255	E257K	257	Missense	proximal	2	no	8.229	8.271	EPSD	ICGC;COSMIC	5.604	Up-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	P39748	FEN1	O14757	CHEK1	S255	R262Q	262	Missense	distal	7	no	8.229	8.384	EPSD	ICGC;COSMIC	5.604	Up-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	P39748	FEN1	O14757	CHEK1	S255	D248N	248	Missense	distal	-7	no	8.229	7.922	EPSD	ICGC	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	P39748	FEN1	O14757	CHEK1	S335	G338V	338	Missense	distal	3	no	8.627	9.053	EPSD	ICGC	5.604	Up-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	P39748	FEN1	O14757	CHEK1	S335	R339L	339	Missense	distal	4	no	8.627	8.613	EPSD	ICGC	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q13263	TRIM28	O14757	CHEK1	S14	S9L	9	Missense	distal	-5	no	5.000	8.188	EPSD	ICGC	5.604	Gain
CAMK_CAMKL_CHK1_CHEK1_ST	Q13263	TRIM28	O14757	CHEK1	T34	A40V	40	Missense	distal	6	no	5.619	5.507	EPSD	ICGC	5.604	Loss
CAMK_CAMKL_CHK1_CHEK1_ST	Q13263	TRIM28	O14757	CHEK1	T34	A38S	38	Missense	distal	4	no	5.619	5.425	EPSD	ICGC;COSMIC	5.604	Loss
CAMK_CAMKL_CHK1_CHEK1_ST	Q13263	TRIM28	O14757	CHEK1	S285	V284M	284	Missense	proximal	-1	no	8.908	8.864	EPSD	ICGC	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q13263	TRIM28	O14757	CHEK1	T415	P413L	413	Missense	proximal	-2	no	5.657	5.478	EPSD	ICGC	5.604	Loss
CAMK_CAMKL_CHK1_CHEK1_ST	Q13263	TRIM28	O14757	CHEK1	T415	R412C	412	Missense	distal	-3	no	5.657	-2.434	EPSD	ICGC;COSMIC	5.604	Loss
CAMK_CAMKL_CHK1_CHEK1_ST	Q13263	TRIM28	O14757	CHEK1	S473	G476S	476	Missense	distal	3	no	8.214	8.301	PhosphoSitePlus	ICGC;COSMIC	5.604	Up-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q13263	TRIM28	O14757	CHEK1	S594	S598N	598	Missense	distal	4	no	8.218	8.237	EPSD	ICGC;GDSC;CCLE	5.604	Up-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q13263	TRIM28	O14757	CHEK1	S752	Y755N	755	Missense	distal	3	no	6.033	8.102	EPSD	ICGC	5.604	Up-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q13263	TRIM28	O14757	CHEK1	S756	Y755N	755	Missense	proximal	-1	no	8.323	8.212	EPSD	ICGC	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q13263	TRIM28	O14757	CHEK1	S757	Y755N	755	Missense	proximal	-2	no	5.588	5.664	EPSD	ICGC	5.604	Gain
CAMK_CAMKL_CHK1_CHEK1_ST	P49792	RANBP2	O14757	CHEK1	S26	S26L	26	Missense	central	0	yes	10.697	0.000	EPSD	ICGC;COSMIC	5.604	Loss
CAMK_CAMKL_CHK1_CHEK1_ST	P49792	RANBP2	O14757	CHEK1	S26	P20Q	20	Missense	distal	-6	no	10.697	10.601	EPSD	ICGC;COSMIC	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	P49792	RANBP2	O14757	CHEK1	S313	A311T	311	Missense	proximal	-2	no	7.683	7.822	EPSD	ICGC;COSMIC	5.604	Up-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	P49792	RANBP2	O14757	CHEK1	S313	R310Q	310	Missense	distal	-3	no	7.683	0.476	EPSD	ICGC;COSMIC	5.604	Loss
CAMK_CAMKL_CHK1_CHEK1_ST	P49792	RANBP2	O14757	CHEK1	S767	P761L	761	Missense	distal	-6	no	6.870	6.797	EPSD	ICGC	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	P49792	RANBP2	O14757	CHEK1	S948	P941S	941	Missense	distal	-7	no	5.221	5.891	EPSD	ICGC	5.604	Gain
CAMK_CAMKL_CHK1_CHEK1_ST	P49792	RANBP2	O14757	CHEK1	T1146	V1141L	1141	Missense	distal	-5	no	2.256	5.733	EPSD	ICGC	5.604	Gain
CAMK_CAMKL_CHK1_CHEK1_ST	P49792	RANBP2	O14757	CHEK1	T1226	V1219L	1219	Missense	distal	-7	no	10.522	9.844	EPSD	ICGC;COSMIC	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	P49792	RANBP2	O14757	CHEK1	T1226	K1229E	1229	Missense	distal	3	no	10.522	11.338	EPSD	ICGC	5.604	Up-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	P49792	RANBP2	O14757	CHEK1	T1310	A1315V	1315	Missense	distal	5	no	6.861	6.757	EPSD	ICGC;COSMIC	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	P49792	RANBP2	O14757	CHEK1	S1449	A1444V	1444	Missense	distal	-5	no	5.476	7.915	EPSD	ICGC;COSMIC	5.604	Gain
CAMK_CAMKL_CHK1_CHEK1_ST	P49792	RANBP2	O14757	CHEK1	S1773	I1780M	1780	Missense	distal	7	no	5.636	5.913	EPSD	ICGC	5.604	Up-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	P49792	RANBP2	O14757	CHEK1	S1833	S1835N	1835	Missense	proximal	2	no	6.053	6.235	EPSD	ICGC	5.604	Up-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	P49792	RANBP2	O14757	CHEK1	S1955	F1961C	1961	Missense	distal	6	no	9.165	9.143	EPSD	ICGC	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	P49792	RANBP2	O14757	CHEK1	S1955	T1954S	1954	Missense	proximal	-1	no	9.165	8.960	EPSD	ICGC;COSMIC	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	P49792	RANBP2	O14757	CHEK1	S2835	Q2832R	2832	Missense	distal	-3	no	-1.426	5.781	EPSD	ICGC	5.604	Gain
CAMK_CAMKL_CHK1_CHEK1_ST	Q9BQG0	MYBBP1A	O14757	CHEK1	T79	L81R	81	Missense	proximal	2	no	8.017	8.316	EPSD	ICGC;COSMIC	5.604	Up-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q9BQG0	MYBBP1A	O14757	CHEK1	T79	A73D	73	Missense	distal	-6	no	8.017	7.971	EPSD	ICGC;COSMIC	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q9BQG0	MYBBP1A	O14757	CHEK1	T79	G84W	84	Missense	distal	5	no	8.017	7.936	EPSD	ICGC;COSMIC	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q9BQG0	MYBBP1A	O14757	CHEK1	S399	R393Q	393	Missense	distal	-6	no	7.515	7.597	EPSD	ICGC;COSMIC	5.604	Up-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q9BQG0	MYBBP1A	O14757	CHEK1	S399	R393W	393	Missense	distal	-6	no	7.515	7.835	EPSD	ICGC;COSMIC	5.604	Up-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q9BQG0	MYBBP1A	O14757	CHEK1	S399	V395L	395	Missense	distal	-4	no	7.515	7.267	EPSD	ICGC;COSMIC	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q9BQG0	MYBBP1A	O14757	CHEK1	S399	P401S	401	Missense	proximal	2	no	7.515	7.592	EPSD	ICGC	5.604	Up-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q9BQG0	MYBBP1A	O14757	CHEK1	T637	R633S	633	Missense	distal	-4	no	6.856	6.548	EPSD	ICGC;COSMIC	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q9BQG0	MYBBP1A	O14757	CHEK1	T637	D641Y	641	Missense	distal	4	no	6.856	6.980	EPSD	ICGC;COSMIC	5.604	Up-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q9BQG0	MYBBP1A	O14757	CHEK1	S775	E779K	779	Missense	distal	4	no	8.939	8.933	EPSD	ICGC	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q9BQG0	MYBBP1A	O14757	CHEK1	S864	D870E	870	Missense	distal	6	no	9.189	9.103	EPSD	ICGC;COSMIC	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q9BQG0	MYBBP1A	O14757	CHEK1	T946	V943M	943	Missense	distal	-3	no	2.997	6.312	EPSD	ICGC	5.604	Gain
CAMK_CAMKL_CHK1_CHEK1_ST	Q9BQG0	MYBBP1A	O14757	CHEK1	S979	Y978D	978	Missense	proximal	-1	no	8.367	8.167	EPSD	ICGC;COSMIC	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q9BQG0	MYBBP1A	O14757	CHEK1	S991	M997R	997	Missense	distal	6	no	7.011	6.697	EPSD	ICGC;COSMIC	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q9BQG0	MYBBP1A	O14757	CHEK1	S991	N990D	990	Missense	proximal	-1	no	7.011	6.922	EPSD	ICGC;COSMIC	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q9BQG0	MYBBP1A	O14757	CHEK1	S991	R989C	989	Missense	proximal	-2	no	7.011	6.959	EPSD	ICGC;COSMIC	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q9BQG0	MYBBP1A	O14757	CHEK1	S991	S991R	991	Missense	central	0	yes	7.011	0.000	EPSD	ICGC	5.604	Loss
CAMK_CAMKL_CHK1_CHEK1_ST	Q9BQG0	MYBBP1A	O14757	CHEK1	T994	S991R	991	Missense	distal	-3	no	-1.962	7.734	EPSD	ICGC	5.604	Gain
CAMK_CAMKL_CHK1_CHEK1_ST	Q9BQG0	MYBBP1A	O14757	CHEK1	S1000	M997R	997	Missense	distal	-3	no	6.898	12.047	EPSD	ICGC;COSMIC	5.604	Up-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q9BQG0	MYBBP1A	O14757	CHEK1	S1000	H1005N	1005	Missense	distal	5	no	6.898	6.984	EPSD	ICGC	5.604	Up-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q9BQG0	MYBBP1A	O14757	CHEK1	S1243	P1245S	1245	Missense	proximal	2	no	8.906	8.983	EPSD	ICGC;COSMIC	5.604	Up-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q9BQG0	MYBBP1A	O14757	CHEK1	S1243	A1237T	1237	Missense	distal	-6	no	8.906	9.101	EPSD	ICGC;COSMIC	5.604	Up-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q9BQG0	MYBBP1A	O14757	CHEK1	S1310	S1310I	1310	Missense	central	0	yes	10.671	0.000	PhosphoSitePlus	ICGC;COSMIC	5.604	Loss
CAMK_CAMKL_CHK1_CHEK1_ST	Q9BQG0	MYBBP1A	O14757	CHEK1	S1310	S1303F	1303	Missense	distal	-7	no	10.671	8.939	PhosphoSitePlus	ICGC;COSMIC;GDSC;CCLE	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q9HC62	SENP2	O14757	CHEK1	S32	L27Q	27	Missense	distal	-5	no	14.222	10.849	EPSD	ICGC;COSMIC	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q9HC62	SENP2	O14757	CHEK1	S34	L27Q	27	Missense	distal	-7	no	10.144	11.026	EPSD	ICGC;COSMIC	5.604	Up-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q9HC62	SENP2	O14757	CHEK1	S168	G164V	164	Missense	distal	-4	no	11.559	11.525	EPSD	ICGC	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q9HC62	SENP2	O14757	CHEK1	S333	G332C	332	Missense	proximal	-1	no	11.612	11.630	EPSD	ICGC	5.604	Up-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q08AD1	CAMSAP2	O14757	CHEK1	S86	A93T	93	Missense	distal	7	no	9.242	9.126	EPSD	ICGC;COSMIC	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q08AD1	CAMSAP2	O14757	CHEK1	S86	I88V	88	Missense	proximal	2	no	9.242	9.642	EPSD	ICGC;COSMIC	5.604	Up-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q08AD1	CAMSAP2	O14757	CHEK1	S86	A84S	84	Missense	proximal	-2	no	9.242	9.127	EPSD	ICGC	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q08AD1	CAMSAP2	O14757	CHEK1	S415	I411S	411	Missense	distal	-4	no	9.017	8.997	EPSD	ICGC;COSMIC	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q08AD1	CAMSAP2	O14757	CHEK1	S416	I411S	411	Missense	distal	-5	no	8.725	7.569	EPSD	ICGC;COSMIC	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q08AD1	CAMSAP2	O14757	CHEK1	S434	W427C	427	Missense	distal	-7	no	5.439	6.257	EPSD	ICGC	5.604	Gain
CAMK_CAMKL_CHK1_CHEK1_ST	Q08AD1	CAMSAP2	O14757	CHEK1	S464	G458E	458	Missense	distal	-6	no	9.056	8.897	PhosphoSitePlus	ICGC;COSMIC	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q08AD1	CAMSAP2	O14757	CHEK1	S464	R457L	457	Missense	distal	-7	no	9.056	8.432	PhosphoSitePlus	ICGC;COSMIC	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q08AD1	CAMSAP2	O14757	CHEK1	S464	R461H	461	Missense	distal	-3	no	9.056	3.247	PhosphoSitePlus	ICGC;COSMIC	5.604	Loss
CAMK_CAMKL_CHK1_CHEK1_ST	Q08AD1	CAMSAP2	O14757	CHEK1	S639	M634I	634	Missense	distal	-5	no	4.765	7.107	EPSD	ICGC;COSMIC	5.604	Gain
CAMK_CAMKL_CHK1_CHEK1_ST	Q08AD1	CAMSAP2	O14757	CHEK1	T644	D642N	642	Missense	proximal	-2	no	9.236	9.378	EPSD	ICGC;COSMIC	5.604	Up-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q08AD1	CAMSAP2	O14757	CHEK1	S677	P674S	674	Missense	distal	-3	no	5.615	3.056	EPSD	ICGC;COSMIC	5.604	Loss
CAMK_CAMKL_CHK1_CHEK1_ST	Q08AD1	CAMSAP2	O14757	CHEK1	S728	Q721K	721	Missense	distal	-7	no	4.785	5.707	EPSD	ICGC;COSMIC	5.604	Gain
CAMK_CAMKL_CHK1_CHEK1_ST	Q08AD1	CAMSAP2	O14757	CHEK1	S844	D847N	847	Missense	distal	3	no	7.017	6.301	EPSD	ICGC;COSMIC	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q08AD1	CAMSAP2	O14757	CHEK1	S844	G839V	839	Missense	distal	-5	no	7.017	6.682	EPSD	ICGC;COSMIC	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q08AD1	CAMSAP2	O14757	CHEK1	S900	S894A	894	Missense	distal	-6	no	7.439	7.313	EPSD	ICGC;COSMIC	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q08AD1	CAMSAP2	O14757	CHEK1	S980	S980Y	980	Missense	central	0	yes	6.922	0.000	EPSD	ICGC;COSMIC	5.604	Loss
CAMK_CAMKL_CHK1_CHEK1_ST	Q08AD1	CAMSAP2	O14757	CHEK1	S980	R987K	987	Missense	distal	7	no	6.922	6.998	EPSD	ICGC;COSMIC	5.604	Up-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q08AD1	CAMSAP2	O14757	CHEK1	T1004	R1001Q	1001	Missense	distal	-3	no	9.217	2.010	EPSD	ICGC;COSMIC	5.604	Loss
CAMK_CAMKL_CHK1_CHEK1_ST	Q08AD1	CAMSAP2	O14757	CHEK1	T1004	R1007L	1007	Missense	distal	3	no	9.217	8.785	EPSD	ICGC	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q08AD1	CAMSAP2	O14757	CHEK1	S1008	R1014W	1014	Missense	distal	6	no	5.241	5.708	EPSD	ICGC	5.604	Gain
CAMK_CAMKL_CHK1_CHEK1_ST	Q08AD1	CAMSAP2	O14757	CHEK1	S1019	R1014W	1014	Missense	distal	-5	no	8.023	7.164	EPSD	ICGC	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q08AD1	CAMSAP2	O14757	CHEK1	S1019	L1012F	1012	Missense	distal	-7	no	8.023	7.175	EPSD	ICGC;COSMIC	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q08AD1	CAMSAP2	O14757	CHEK1	S1019	S1021I	1021	Missense	proximal	2	no	8.023	7.516	EPSD	ICGC	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q08AD1	CAMSAP2	O14757	CHEK1	S1019	P1024S	1024	Missense	distal	5	no	8.023	8.104	EPSD	ICGC;COSMIC	5.604	Up-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q08AD1	CAMSAP2	O14757	CHEK1	S1268	Q1261K	1261	Missense	distal	-7	no	9.792	10.714	EPSD	ICGC;COSMIC	5.604	Up-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q08AD1	CAMSAP2	O14757	CHEK1	S1268	R1271T	1271	Missense	distal	3	no	9.792	9.651	EPSD	ICGC;COSMIC	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q08AD1	CAMSAP2	O14757	CHEK1	S1268	H1273Y	1273	Missense	distal	5	no	9.792	9.425	EPSD	ICGC	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q08AD1	CAMSAP2	O14757	CHEK1	S1313	K1306N	1306	Missense	distal	-7	no	9.915	8.457	EPSD	ICGC;COSMIC	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q08AD1	CAMSAP2	O14757	CHEK1	S1313	R1307S	1307	Missense	distal	-6	no	9.915	9.995	EPSD	ICGC;COSMIC	5.604	Up-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	P30305	CDC25B	O14757	CHEK1	S151	M152V	152	Missense	proximal	1	no	9.075	9.082	EPSD	ICGC;COSMIC	5.604	Up-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	P30305	CDC25B	O14757	CHEK1	T167	Q170H	170	Missense	distal	3	no	7.142	6.110	EPSD	ICGC;COSMIC	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	P30305	CDC25B	O14757	CHEK1	S230	S229R	229	Missense	proximal	-1	no	9.172	9.334	EPSD;PhosphoSitePlus	ICGC;COSMIC	5.604	Up-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	P30305	CDC25B	O14757	CHEK1	S230	P232T	232	Missense	proximal	2	no	9.172	8.857	EPSD;PhosphoSitePlus	ICGC;COSMIC	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	P30305	CDC25B	O14757	CHEK1	S323	M324R	324	Missense	proximal	1	no	8.657	8.697	EPSD	ICGC;COSMIC	5.604	Up-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	P30305	CDC25B	O14757	CHEK1	S323	R320C	320	Missense	distal	-3	no	8.657	0.566	EPSD	ICGC	5.604	Loss
CAMK_CAMKL_CHK1_CHEK1_ST	P30305	CDC25B	O14757	CHEK1	S375	E382G	382	Missense	distal	7	no	9.149	8.914	EPSD	ICGC;COSMIC	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	P30305	CDC25B	O14757	CHEK1	T561	L554I	554	Missense	distal	-7	no	5.539	5.781	EPSD	ICGC	5.604	Gain
CAMK_CAMKL_CHK1_CHEK1_ST	P30305	CDC25B	O14757	CHEK1	S563	S563C	563	Missense	central	0	yes	6.380	0.000	PhosphoSitePlus;EPSD	ICGC;COSMIC	5.604	Loss
CAMK_CAMKL_CHK1_CHEK1_ST	P30305	CDC25B	O14757	CHEK1	S563	W564L	564	Missense	proximal	1	no	6.380	6.375	PhosphoSitePlus;EPSD	ICGC;COSMIC	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q5JSZ5	PRRC2B	O14757	CHEK1	S104	S104Y	104	Missense	central	0	yes	5.996	0.000	EPSD	ICGC;COSMIC	5.604	Loss
CAMK_CAMKL_CHK1_CHEK1_ST	Q5JSZ5	PRRC2B	O14757	CHEK1	S104	P106L	106	Missense	proximal	2	no	5.996	5.679	EPSD	ICGC;COSMIC	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q5JSZ5	PRRC2B	O14757	CHEK1	S104	S100I	100	Missense	distal	-4	no	5.996	6.016	EPSD	ICGC	5.604	Up-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q5JSZ5	PRRC2B	O14757	CHEK1	S104	E108G	108	Missense	distal	4	no	5.996	6.105	EPSD	ICGC;COSMIC	5.604	Up-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q5JSZ5	PRRC2B	O14757	CHEK1	S120	P113R	113	Missense	distal	-7	no	8.802	9.212	EPSD	ICGC	5.604	Up-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q5JSZ5	PRRC2B	O14757	CHEK1	S120	P125Q	125	Missense	distal	5	no	8.802	8.856	EPSD	ICGC;COSMIC	5.604	Up-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q5JSZ5	PRRC2B	O14757	CHEK1	S166	R163Q	163	Missense	distal	-3	no	9.677	2.470	PhosphoSitePlus	ICGC;COSMIC	5.604	Loss
CAMK_CAMKL_CHK1_CHEK1_ST	Q5JSZ5	PRRC2B	O14757	CHEK1	S166	G160V	160	Missense	distal	-6	no	9.677	9.651	PhosphoSitePlus	ICGC;COSMIC	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q5JSZ5	PRRC2B	O14757	CHEK1	S166	P173Q	173	Missense	distal	7	no	9.677	9.869	PhosphoSitePlus	ICGC;COSMIC	5.604	Up-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q5JSZ5	PRRC2B	O14757	CHEK1	S236	S232I	232	Missense	distal	-4	no	12.090	12.110	EPSD	ICGC	5.604	Up-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q5JSZ5	PRRC2B	O14757	CHEK1	S236	E229D	229	Missense	distal	-7	no	12.090	11.636	EPSD	ICGC;COSMIC	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q5JSZ5	PRRC2B	O14757	CHEK1	S416	M417V	417	Missense	proximal	1	no	8.835	8.842	EPSD	ICGC;COSMIC	5.604	Up-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q5JSZ5	PRRC2B	O14757	CHEK1	S416	Q414H	414	Missense	proximal	-2	no	8.835	8.853	EPSD	ICGC	5.604	Up-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q5JSZ5	PRRC2B	O14757	CHEK1	S416	R411W	411	Missense	distal	-5	no	8.835	7.976	EPSD	ICGC;COSMIC	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q5JSZ5	PRRC2B	O14757	CHEK1	S416	Q412H	412	Missense	distal	-4	no	8.835	8.477	EPSD	ICGC	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q5JSZ5	PRRC2B	O14757	CHEK1	S480	E482Q	482	Missense	proximal	2	no	7.562	7.447	EPSD	ICGC	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q5JSZ5	PRRC2B	O14757	CHEK1	T736	P729S	729	Missense	distal	-7	no	6.742	7.412	EPSD	ICGC;COSMIC	5.604	Up-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q5JSZ5	PRRC2B	O14757	CHEK1	S778	A782S	782	Missense	distal	4	no	7.062	6.868	EPSD	ICGC	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q5JSZ5	PRRC2B	O14757	CHEK1	S778	S783P	783	Missense	distal	5	no	7.062	6.980	EPSD	ICGC;COSMIC	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q5JSZ5	PRRC2B	O14757	CHEK1	S874	W871R	871	Missense	distal	-3	no	-22.249	11.355	EPSD	ICGC;COSMIC	5.604	Gain
CAMK_CAMKL_CHK1_CHEK1_ST	Q5JSZ5	PRRC2B	O14757	CHEK1	T895	S901F	901	Missense	distal	6	no	6.965	7.368	EPSD	ICGC;COSMIC;GDSC	5.604	Up-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q5JSZ5	PRRC2B	O14757	CHEK1	S1086	G1083R	1083	Missense	distal	-3	no	-1.000	6.774	EPSD	ICGC	5.604	Gain
CAMK_CAMKL_CHK1_CHEK1_ST	Q5JSZ5	PRRC2B	O14757	CHEK1	S1132	S1136I	1136	Missense	distal	4	no	10.231	10.283	EPSD	ICGC;COSMIC	5.604	Up-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q5JSZ5	PRRC2B	O14757	CHEK1	S1235	E1238K	1238	Missense	distal	3	no	5.912	5.096	EPSD	ICGC	5.604	Loss
CAMK_CAMKL_CHK1_CHEK1_ST	Q5JSZ5	PRRC2B	O14757	CHEK1	S1235	S1229N	1229	Missense	distal	-6	no	5.912	5.953	EPSD	ICGC;COSMIC	5.604	Up-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q5JSZ5	PRRC2B	O14757	CHEK1	T1251	R1248Q	1248	Missense	distal	-3	no	9.182	1.975	EPSD	ICGC;COSMIC	5.604	Loss
CAMK_CAMKL_CHK1_CHEK1_ST	Q5JSZ5	PRRC2B	O14757	CHEK1	S1422	D1429E	1429	Missense	distal	7	no	9.656	9.599	EPSD	ICGC;COSMIC	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q5JSZ5	PRRC2B	O14757	CHEK1	S1422	S1422F	1422	Missense	central	0	yes	9.656	0.000	EPSD	ICGC	5.604	Loss
CAMK_CAMKL_CHK1_CHEK1_ST	Q5JSZ5	PRRC2B	O14757	CHEK1	S1422	E1415D	1415	Missense	distal	-7	no	9.656	9.203	EPSD	ICGC	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q5JSZ5	PRRC2B	O14757	CHEK1	S1458	T1463A	1463	Missense	distal	5	no	10.513	10.754	EPSD	ICGC	5.604	Up-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q5JSZ5	PRRC2B	O14757	CHEK1	S1458	P1454T	1454	Missense	distal	-4	no	10.513	10.226	EPSD	ICGC;COSMIC	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q5JSZ5	PRRC2B	O14757	CHEK1	S1470	T1463A	1463	Missense	distal	-7	no	7.134	8.450	EPSD	ICGC	5.604	Up-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	P02545	LMNA	O14757	CHEK1	T10	G13E	13	Missense	distal	3	no	7.061	8.609	EPSD	ICGC	5.604	Up-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	P02545	LMNA	O14757	CHEK1	S51	R50L	50	Missense	proximal	-1	no	9.757	9.857	EPSD	ICGC;COSMIC	5.604	Up-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	P02545	LMNA	O14757	CHEK1	S268	E262D	262	Missense	distal	-6	no	11.876	11.826	EPSD	ICGC	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	P02545	LMNA	O14757	CHEK1	S458	D461G	461	Missense	distal	3	no	9.534	7.889	EPSD	ICGC	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	P02545	LMNA	O14757	CHEK1	T548	R545C	545	Missense	distal	-3	no	12.081	3.990	EPSD	ICGC;COSMIC	5.604	Loss
CAMK_CAMKL_CHK1_CHEK1_ST	P02545	LMNA	O14757	CHEK1	T548	R545L	545	Missense	distal	-3	no	12.081	-6.465	EPSD	ICGC	5.604	Loss
CAMK_CAMKL_CHK1_CHEK1_ST	O15151	MDM4	O14757	CHEK1	S96	D100G	100	Missense	distal	4	no	6.210	6.226	EPSD	ICGC;COSMIC	5.604	Up-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	O15151	MDM4	O14757	CHEK1	S342	I349T	349	Missense	distal	7	no	8.442	8.667	PhosphoSitePlus;EPSD	ICGC;COSMIC	5.604	Up-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	O95625	ZBTB11	O14757	CHEK1	S442	E444D	444	Missense	proximal	2	no	5.826	5.744	EPSD	ICGC;COSMIC	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	O95625	ZBTB11	O14757	CHEK1	S511	V512F	512	Missense	proximal	1	no	9.371	9.372	EPSD;PhosphoSitePlus	ICGC;COSMIC	5.604	Up-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	O95625	ZBTB11	O14757	CHEK1	S511	R508Q	508	Missense	distal	-3	no	9.371	2.164	EPSD;PhosphoSitePlus	ICGC;COSMIC	5.604	Loss
CAMK_CAMKL_CHK1_CHEK1_ST	O95625	ZBTB11	O14757	CHEK1	S511	R510H	510	Missense	proximal	-1	no	9.371	9.496	EPSD;PhosphoSitePlus	ICGC;COSMIC	5.604	Up-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	O95625	ZBTB11	O14757	CHEK1	S537	V534F	534	Missense	distal	-3	no	5.926	5.717	PhosphoSitePlus;EPSD	ICGC;COSMIC	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	O95625	ZBTB11	O14757	CHEK1	S537	A538T	538	Missense	proximal	1	no	5.926	5.915	PhosphoSitePlus;EPSD	ICGC	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	O95625	ZBTB11	O14757	CHEK1	S537	Q544E	544	Missense	distal	7	no	5.926	6.012	PhosphoSitePlus;EPSD	ICGC;COSMIC	5.604	Up-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	O95625	ZBTB11	O14757	CHEK1	T909	T907K	907	Missense	proximal	-2	no	7.303	6.967	EPSD	ICGC	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q9UPP1	PHF8	O14757	CHEK1	S874	D876V	876	Missense	proximal	2	no	6.172	5.599	EPSD	ICGC;COSMIC	5.604	Loss
CAMK_CAMKL_CHK1_CHEK1_ST	Q9UPP1	PHF8	O14757	CHEK1	T1007	A1002S	1002	Missense	distal	-5	no	4.458	7.186	EPSD	ICGC;COSMIC	5.604	Gain
CAMK_CAMKL_CHK1_CHEK1_ST	Q9UPP1	PHF8	O14757	CHEK1	S1021	R1018I	1018	Missense	distal	-3	no	11.227	2.469	EPSD	ICGC;COSMIC	5.604	Loss
CAMK_CAMKL_CHK1_CHEK1_ST	Q9H0H5	RACGAP1	O14757	CHEK1	T145	S151F	151	Missense	distal	6	no	9.217	9.620	EPSD	ICGC	5.604	Up-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q9H0H5	RACGAP1	O14757	CHEK1	S234	E231K	231	Missense	distal	-3	no	2.520	5.783	EPSD	ICGC;COSMIC	5.604	Gain
CAMK_CAMKL_CHK1_CHEK1_ST	Q9H0H5	RACGAP1	O14757	CHEK1	S257	T260N	260	Missense	distal	3	no	5.844	6.828	EPSD	ICGC	5.604	Up-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q9H0H5	RACGAP1	O14757	CHEK1	S257	L261M	261	Missense	distal	4	no	5.844	5.918	EPSD	ICGC	5.604	Up-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q9H0H5	RACGAP1	O14757	CHEK1	T272	G276D	276	Missense	distal	4	no	7.235	7.218	EPSD	ICGC;COSMIC	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q9H0H5	RACGAP1	O14757	CHEK1	S299	P302L	302	Missense	distal	3	no	7.389	6.625	EPSD	ICGC	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q9H0H5	RACGAP1	O14757	CHEK1	S533	S540N	540	Missense	distal	7	no	9.239	9.468	EPSD	ICGC	5.604	Up-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q9H0H5	RACGAP1	O14757	CHEK1	S533	E529G	529	Missense	distal	-4	no	9.239	9.062	EPSD	ICGC	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q9H0H5	RACGAP1	O14757	CHEK1	S590	R597T	597	Missense	distal	7	no	8.547	8.387	EPSD	ICGC;COSMIC	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q9H0H5	RACGAP1	O14757	CHEK1	S600	R597T	597	Missense	distal	-3	no	9.329	-11.240	EPSD	ICGC;COSMIC	5.604	Loss
CAMK_CAMKL_CHK1_CHEK1_ST	Q9H0H5	RACGAP1	O14757	CHEK1	S611	S613I	613	Missense	proximal	2	no	8.941	8.434	EPSD	ICGC;COSMIC	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q86UE8	TLK2	O14757	CHEK1	S115	R109G	109	Missense	distal	-6	no	5.865	5.982	EPSD	ICGC;COSMIC	5.604	Up-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q86UE8	TLK2	O14757	CHEK1	S115	R109L	109	Missense	distal	-6	no	5.865	5.969	EPSD	ICGC;COSMIC	5.604	Up-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q92974	ARHGEF2	O14757	CHEK1	T103	N102K	102	Missense	proximal	-1	no	9.192	8.987	EPSD	ICGC	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q92974	ARHGEF2	O14757	CHEK1	T103	A97T	97	Missense	distal	-6	no	9.192	9.388	EPSD	ICGC	5.604	Up-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q92974	ARHGEF2	O14757	CHEK1	S142	R139S	139	Missense	distal	-3	no	6.650	-3.046	EPSD	ICGC	5.604	Loss
CAMK_CAMKL_CHK1_CHEK1_ST	Q92974	ARHGEF2	O14757	CHEK1	S172	R169L	169	Missense	distal	-3	no	10.777	-7.769	PhosphoSitePlus	ICGC;COSMIC	5.604	Loss
CAMK_CAMKL_CHK1_CHEK1_ST	Q92974	ARHGEF2	O14757	CHEK1	S295	R301C	301	Missense	distal	6	no	5.428	5.722	EPSD	ICGC	5.604	Gain
CAMK_CAMKL_CHK1_CHEK1_ST	Q92974	ARHGEF2	O14757	CHEK1	S719	S722C	722	Missense	distal	3	no	10.291	9.341	EPSD	ICGC	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q9Y570	PPME1	O14757	CHEK1	S15	P18S	18	Missense	distal	3	no	13.534	13.205	PhosphoSitePlus	ICGC;COSMIC	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q9Y570	PPME1	O14757	CHEK1	S15	R12L	12	Missense	distal	-3	no	13.534	-5.012	PhosphoSitePlus	ICGC	5.604	Loss
CAMK_CAMKL_CHK1_CHEK1_ST	Q9Y570	PPME1	O14757	CHEK1	S15	R16L	16	Missense	proximal	1	no	13.534	13.500	PhosphoSitePlus	ICGC	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q9Y570	PPME1	O14757	CHEK1	S15	S15Y	15	Missense	central	0	yes	13.534	0.000	PhosphoSitePlus	ICGC;COSMIC	5.604	Loss
CAMK_CAMKL_CHK1_CHEK1_ST	Q9Y570	PPME1	O14757	CHEK1	S42	R39Q	39	Missense	distal	-3	no	9.468	2.261	EPSD	ICGC;COSMIC;GDSC;CCLE	5.604	Loss
CAMK_CAMKL_CHK1_CHEK1_ST	Q9Y570	PPME1	O14757	CHEK1	S42	S42P	42	Missense	central	0	yes	9.468	0.000	EPSD	ICGC	5.604	Loss
CAMK_CAMKL_CHK1_CHEK1_ST	Q9Y570	PPME1	O14757	CHEK1	S306	N307S	307	Missense	proximal	1	no	8.610	8.613	EPSD	ICGC	5.604	Up-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	P27816	MAP4	O14757	CHEK1	T324	P323H	323	Missense	proximal	-1	no	8.033	7.873	EPSD	ICGC	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	P27816	MAP4	O14757	CHEK1	T324	A331D	331	Missense	distal	7	no	8.033	8.375	EPSD	ICGC	5.604	Up-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	P27816	MAP4	O14757	CHEK1	S602	D604G	604	Missense	proximal	2	no	8.609	8.078	EPSD	ICGC	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	P27816	MAP4	O14757	CHEK1	S602	D604Y	604	Missense	proximal	2	no	8.609	7.846	EPSD	ICGC;COSMIC	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	P27816	MAP4	O14757	CHEK1	S742	P749Q	749	Missense	distal	7	no	6.278	6.470	EPSD	ICGC;COSMIC	5.604	Up-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	P27816	MAP4	O14757	CHEK1	S742	A744S	744	Missense	proximal	2	no	6.278	5.822	EPSD	ICGC;COSMIC	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	P27816	MAP4	O14757	CHEK1	S801	S801Y	801	Missense	central	0	yes	6.145	0.000	EPSD	ICGC	5.604	Loss
CAMK_CAMKL_CHK1_CHEK1_ST	P27816	MAP4	O14757	CHEK1	T835	K838N	838	Missense	distal	3	no	6.856	7.053	EPSD	ICGC;COSMIC	5.604	Up-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	P27816	MAP4	O14757	CHEK1	S863	S867G	867	Missense	distal	4	no	11.041	11.108	EPSD	ICGC;COSMIC	5.604	Up-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	P27816	MAP4	O14757	CHEK1	T900	D905E	905	Missense	distal	5	no	5.698	5.697	EPSD	ICGC	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	P27816	MAP4	O14757	CHEK1	T900	P902T	902	Missense	proximal	2	no	5.698	5.383	EPSD	ICGC;COSMIC	5.604	Loss
CAMK_CAMKL_CHK1_CHEK1_ST	P27816	MAP4	O14757	CHEK1	T900	P902S	902	Missense	proximal	2	no	5.698	5.775	EPSD	ICGC	5.604	Up-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	P27816	MAP4	O14757	CHEK1	T909	D905E	905	Missense	distal	-4	no	7.205	7.346	EPSD	ICGC	5.604	Up-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	P27816	MAP4	O14757	CHEK1	T909	P902T	902	Missense	distal	-7	no	7.205	7.008	EPSD	ICGC;COSMIC	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	P27816	MAP4	O14757	CHEK1	T909	P902S	902	Missense	distal	-7	no	7.205	7.875	EPSD	ICGC	5.604	Up-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	P27816	MAP4	O14757	CHEK1	S941	G940R	940	Missense	proximal	-1	no	7.208	7.191	EPSD	ICGC;COSMIC	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	P27816	MAP4	O14757	CHEK1	S941	T942M	942	Missense	proximal	1	no	7.208	7.186	EPSD	ICGC;COSMIC	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	P27816	MAP4	O14757	CHEK1	S941	R936S	936	Missense	distal	-5	no	7.208	6.996	EPSD	ICGC;COSMIC	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	P27816	MAP4	O14757	CHEK1	S996	G990W	990	Missense	distal	-6	no	5.698	5.900	EPSD	ICGC;COSMIC	5.604	Up-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	P27816	MAP4	O14757	CHEK1	S996	I994V	994	Missense	proximal	-2	no	5.698	5.761	EPSD	ICGC	5.604	Up-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	P27816	MAP4	O14757	CHEK1	S1073	D1075N	1075	Missense	proximal	2	no	7.338	7.053	EPSD	ICGC	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	P27816	MAP4	O14757	CHEK1	S1073	H1079N	1079	Missense	distal	6	no	7.338	7.097	EPSD	ICGC	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	P27816	MAP4	O14757	CHEK1	S1073	G1078D	1078	Missense	distal	5	no	7.338	7.616	EPSD	ICGC;COSMIC	5.604	Up-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q00341	HDLBP	O14757	CHEK1	T149	A156G	156	Missense	distal	7	no	6.467	6.517	EPSD	ICGC	5.604	Up-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q00341	HDLBP	O14757	CHEK1	T149	T154N	154	Missense	distal	5	no	6.467	6.688	EPSD	ICGC	5.604	Up-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q00341	HDLBP	O14757	CHEK1	T149	A156S	156	Missense	distal	7	no	6.467	6.418	EPSD	ICGC;COSMIC	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q00341	HDLBP	O14757	CHEK1	S611	K605T	605	Missense	distal	-6	no	10.896	11.056	EPSD	ICGC;COSMIC	5.604	Up-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q00341	HDLBP	O14757	CHEK1	S706	G704C	704	Missense	proximal	-2	no	10.384	10.298	EPSD	ICGC;COSMIC	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q00341	HDLBP	O14757	CHEK1	T757	R751S	751	Missense	distal	-6	no	9.881	9.962	EPSD	ICGC;COSMIC	5.604	Up-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q00341	HDLBP	O14757	CHEK1	T842	R839C	839	Missense	distal	-3	no	9.276	1.185	EPSD	ICGC;COSMIC;CCLE	5.604	Loss
CAMK_CAMKL_CHK1_CHEK1_ST	Q00341	HDLBP	O14757	CHEK1	T842	R839S	839	Missense	distal	-3	no	9.276	-0.420	EPSD	ICGC	5.604	Loss
CAMK_CAMKL_CHK1_CHEK1_ST	Q00341	HDLBP	O14757	CHEK1	S904	R901W	901	Missense	distal	-3	no	11.035	-22.568	EPSD	ICGC;COSMIC	5.604	Loss
CAMK_CAMKL_CHK1_CHEK1_ST	Q00341	HDLBP	O14757	CHEK1	S904	Q898K	898	Missense	distal	-6	no	11.035	10.943	EPSD	ICGC;COSMIC	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q00341	HDLBP	O14757	CHEK1	S1236	W1233R	1233	Missense	distal	-3	no	-26.200	7.403	EPSD	ICGC;COSMIC	5.604	Gain
CAMK_CAMKL_CHK1_CHEK1_ST	Q00341	HDLBP	O14757	CHEK1	S1245	S1246G	1246	Missense	proximal	1	no	7.392	7.409	EPSD	ICGC;COSMIC	5.604	Up-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q00341	HDLBP	O14757	CHEK1	S1245	F1250S	1250	Missense	distal	5	no	7.392	7.717	EPSD	ICGC	5.604	Up-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q86WR7	PROSER2	O14757	CHEK1	S27	S34R	34	Missense	distal	7	no	7.358	7.450	EPSD	ICGC;COSMIC	5.604	Up-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q86WR7	PROSER2	O14757	CHEK1	S27	R22K	22	Missense	distal	-5	no	7.358	8.533	EPSD	ICGC;COSMIC	5.604	Up-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q86WR7	PROSER2	O14757	CHEK1	S31	S34R	34	Missense	distal	3	no	5.817	5.815	EPSD	ICGC;COSMIC	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q86WR7	PROSER2	O14757	CHEK1	S31	S37I	37	Missense	distal	6	no	5.817	5.860	EPSD	ICGC	5.604	Up-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q86WR7	PROSER2	O14757	CHEK1	S31	R35P	35	Missense	distal	4	no	5.817	5.907	EPSD	ICGC;COSMIC	5.604	Up-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q86WR7	PROSER2	O14757	CHEK1	S37	S34R	34	Missense	distal	-3	no	0.432	10.128	EPSD	ICGC;COSMIC	5.604	Gain
CAMK_CAMKL_CHK1_CHEK1_ST	Q86WR7	PROSER2	O14757	CHEK1	S38	S34R	34	Missense	distal	-4	no	6.454	6.762	EPSD	ICGC;COSMIC	5.604	Up-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q86WR7	PROSER2	O14757	CHEK1	S38	S37I	37	Missense	proximal	-1	no	6.454	6.572	EPSD	ICGC	5.604	Up-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q86WR7	PROSER2	O14757	CHEK1	S38	R40L	40	Missense	proximal	2	no	6.454	6.155	EPSD	ICGC	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q86WR7	PROSER2	O14757	CHEK1	S38	R42K	42	Missense	distal	4	no	6.454	6.356	EPSD	ICGC;COSMIC	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q86WR7	PROSER2	O14757	CHEK1	S38	R35P	35	Missense	distal	-3	no	6.454	-0.683	EPSD	ICGC;COSMIC	5.604	Loss
CAMK_CAMKL_CHK1_CHEK1_ST	Q86WR7	PROSER2	O14757	CHEK1	S43	S37I	37	Missense	distal	-6	no	9.852	9.850	PhosphoSitePlus	ICGC	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q86WR7	PROSER2	O14757	CHEK1	S43	R40L	40	Missense	distal	-3	no	9.852	-8.695	PhosphoSitePlus	ICGC	5.604	Loss
CAMK_CAMKL_CHK1_CHEK1_ST	Q86WR7	PROSER2	O14757	CHEK1	S43	R42K	42	Missense	proximal	-1	no	9.852	9.704	PhosphoSitePlus	ICGC;COSMIC	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q86WR7	PROSER2	O14757	CHEK1	T45	R40L	40	Missense	distal	-5	no	10.315	13.292	EPSD	ICGC	5.604	Up-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q86WR7	PROSER2	O14757	CHEK1	T45	R42K	42	Missense	distal	-3	no	10.315	6.490	EPSD	ICGC;COSMIC	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q86WR7	PROSER2	O14757	CHEK1	S179	R176L	176	Missense	distal	-3	no	7.143	-11.404	EPSD	ICGC	5.604	Loss
CAMK_CAMKL_CHK1_CHEK1_ST	Q86WR7	PROSER2	O14757	CHEK1	S179	A177D	177	Missense	proximal	-2	no	7.143	7.076	EPSD	ICGC;COSMIC	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q14004	CDK13	O14757	CHEK1	S205	K210N	210	Missense	distal	5	no	7.950	7.928	EPSD	ICGC	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q14004	CDK13	O14757	CHEK1	S238	S233N	233	Missense	distal	-5	no	5.799	6.292	EPSD	ICGC;COSMIC	5.604	Up-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q14004	CDK13	O14757	CHEK1	S238	R232H	232	Missense	distal	-6	no	5.799	5.909	EPSD	ICGC;COSMIC;CCLE	5.604	Up-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q14004	CDK13	O14757	CHEK1	S238	S233I	233	Missense	distal	-5	no	5.799	6.956	EPSD	ICGC	5.604	Up-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q14004	CDK13	O14757	CHEK1	S238	V245I	245	Missense	distal	7	no	5.799	5.378	EPSD	ICGC	5.604	Loss
CAMK_CAMKL_CHK1_CHEK1_ST	Q14004	CDK13	O14757	CHEK1	S238	E244Q	244	Missense	distal	6	no	5.799	6.150	EPSD	ICGC;COSMIC	5.604	Up-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q14004	CDK13	O14757	CHEK1	S250	V245I	245	Missense	distal	-5	no	4.632	6.077	EPSD	ICGC	5.604	Gain
CAMK_CAMKL_CHK1_CHEK1_ST	Q14004	CDK13	O14757	CHEK1	S260	S260R	260	Missense	central	0	yes	7.561	0.000	EPSD	ICGC	5.604	Loss
CAMK_CAMKL_CHK1_CHEK1_ST	Q14004	CDK13	O14757	CHEK1	S260	R257C	257	Missense	distal	-3	no	7.561	-0.530	EPSD	ICGC;COSMIC	5.604	Loss
CAMK_CAMKL_CHK1_CHEK1_ST	Q14004	CDK13	O14757	CHEK1	S260	S254G	254	Missense	distal	-6	no	7.561	7.599	EPSD	ICGC;COSMIC	5.604	Up-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q14004	CDK13	O14757	CHEK1	S285	A292S	292	Missense	distal	7	no	11.317	11.268	EPSD	ICGC	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q14004	CDK13	O14757	CHEK1	S315	L319V	319	Missense	distal	4	no	6.182	6.257	EPSD	ICGC;COSMIC	5.604	Up-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q14004	CDK13	O14757	CHEK1	S325	L319V	319	Missense	distal	-6	no	8.291	8.279	EPSD	ICGC;COSMIC	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q14004	CDK13	O14757	CHEK1	S342	R336S	336	Missense	distal	-6	no	5.769	5.849	EPSD	ICGC;COSMIC	5.604	Up-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q14004	CDK13	O14757	CHEK1	S342	K339N	339	Missense	distal	-3	no	5.769	-0.774	EPSD	ICGC	5.604	Loss
CAMK_CAMKL_CHK1_CHEK1_ST	Q14004	CDK13	O14757	CHEK1	S360	S367P	367	Missense	distal	7	no	10.887	10.942	EPSD	ICGC;COSMIC;GDSC	5.604	Up-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q14004	CDK13	O14757	CHEK1	S369	S367P	367	Missense	proximal	-2	no	7.734	8.018	EPSD	ICGC;COSMIC;GDSC	5.604	Up-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q14004	CDK13	O14757	CHEK1	S397	L403F	403	Missense	distal	6	no	8.338	8.331	EPSD	ICGC;COSMIC	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q14004	CDK13	O14757	CHEK1	S413	R418S	418	Missense	distal	5	no	7.332	7.435	EPSD	ICGC	5.604	Up-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q14004	CDK13	O14757	CHEK1	S433	H426N	426	Missense	distal	-7	no	11.421	11.202	EPSD	ICGC;COSMIC	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q14004	CDK13	O14757	CHEK1	S863	G857V	857	Missense	distal	-6	no	12.300	12.274	EPSD	ICGC	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q14004	CDK13	O14757	CHEK1	T871	T876A	876	Missense	distal	5	no	8.053	8.294	EPSD	ICGC;COSMIC	5.604	Up-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q14004	CDK13	O14757	CHEK1	T871	W878C	878	Missense	distal	7	no	8.053	8.149	EPSD	ICGC	5.604	Up-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q14004	CDK13	O14757	CHEK1	T871	I875V	875	Missense	distal	4	no	8.053	8.113	EPSD	ICGC;COSMIC	5.604	Up-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q14004	CDK13	O14757	CHEK1	T1058	Q1060H	1060	Missense	proximal	2	no	7.433	6.923	EPSD	ICGC	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q6T4R5	NHS	O14757	CHEK1	S460	A466T	466	Missense	distal	6	no	8.740	8.662	EPSD	ICGC;COSMIC	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q6T4R5	NHS	O14757	CHEK1	S471	A466T	466	Missense	distal	-5	no	5.591	9.452	EPSD	ICGC;COSMIC	5.604	Gain
CAMK_CAMKL_CHK1_CHEK1_ST	Q6T4R5	NHS	O14757	CHEK1	S566	L563R	563	Missense	distal	-3	no	-4.378	14.169	EPSD	ICGC;COSMIC	5.604	Gain
CAMK_CAMKL_CHK1_CHEK1_ST	Q6T4R5	NHS	O14757	CHEK1	S1062	L1068I	1068	Missense	distal	6	no	10.875	10.509	EPSD	ICGC;COSMIC	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q5JTH9	RRP12	O14757	CHEK1	S23	N27T	27	Missense	distal	4	no	6.161	6.152	EPSD	ICGC;COSMIC;GDSC;CCLE	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q5JTH9	RRP12	O14757	CHEK1	S23	R17Q	17	Missense	distal	-6	no	6.161	6.243	EPSD	ICGC	5.604	Up-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q5JTH9	RRP12	O14757	CHEK1	S23	S23N	23	Missense	central	0	yes	6.161	0.000	EPSD	ICGC;COSMIC	5.604	Loss
CAMK_CAMKL_CHK1_CHEK1_ST	Q5JTH9	RRP12	O14757	CHEK1	S180	P179S	179	Missense	proximal	-1	no	10.028	9.581	EPSD	ICGC;COSMIC	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q5JTH9	RRP12	O14757	CHEK1	S180	F187Y	187	Missense	distal	7	no	10.028	9.944	EPSD	ICGC;COSMIC	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q5JTH9	RRP12	O14757	CHEK1	S180	R177L	177	Missense	distal	-3	no	10.028	-8.518	EPSD	ICGC;COSMIC	5.604	Loss
CAMK_CAMKL_CHK1_CHEK1_ST	Q5JTH9	RRP12	O14757	CHEK1	S180	K186R	186	Missense	distal	6	no	10.028	10.116	EPSD	ICGC;COSMIC	5.604	Up-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q5JTH9	RRP12	O14757	CHEK1	S652	R645L	645	Missense	distal	-7	no	7.770	7.145	EPSD	ICGC;COSMIC	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q5JTH9	RRP12	O14757	CHEK1	S652	R654C	654	Missense	proximal	2	no	7.770	7.504	EPSD	ICGC	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q5JTH9	RRP12	O14757	CHEK1	S737	A744D	744	Missense	distal	7	no	8.407	8.749	EPSD	ICGC	5.604	Up-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q5JTH9	RRP12	O14757	CHEK1	S746	A744D	744	Missense	proximal	-2	no	6.596	6.529	EPSD	ICGC	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q5JTH9	RRP12	O14757	CHEK1	S829	R826Q	826	Missense	distal	-3	no	6.515	-0.692	EPSD	ICGC	5.604	Loss
CAMK_CAMKL_CHK1_CHEK1_ST	Q5JTH9	RRP12	O14757	CHEK1	S829	L825M	825	Missense	distal	-4	no	6.515	6.607	EPSD	ICGC;COSMIC	5.604	Up-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q5JTH9	RRP12	O14757	CHEK1	S829	P831L	831	Missense	proximal	2	no	6.515	6.197	EPSD	ICGC;COSMIC	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q5JTH9	RRP12	O14757	CHEK1	S1049	E1055Q	1055	Missense	distal	6	no	11.218	11.569	PhosphoSitePlus	ICGC;COSMIC	5.604	Up-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q5JTH9	RRP12	O14757	CHEK1	S1049	S1049R	1049	Missense	central	0	yes	11.218	0.000	PhosphoSitePlus	ICGC;COSMIC	5.604	Loss
CAMK_CAMKL_CHK1_CHEK1_ST	Q5JTH9	RRP12	O14757	CHEK1	S1049	E1054K	1054	Missense	distal	5	no	11.218	11.153	PhosphoSitePlus	ICGC;COSMIC	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q5JTH9	RRP12	O14757	CHEK1	S1049	A1047G	1047	Missense	proximal	-2	no	11.218	11.237	PhosphoSitePlus	ICGC;COSMIC	5.604	Up-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q5JTH9	RRP12	O14757	CHEK1	S1049	K1043R	1043	Missense	distal	-6	no	11.218	11.229	PhosphoSitePlus	ICGC;COSMIC	5.604	Up-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q5JTH9	RRP12	O14757	CHEK1	S1105	A1107V	1107	Missense	proximal	2	no	10.895	10.333	EPSD	ICGC;COSMIC;GDSC;CCLE	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q9HAW4	CLSPN	O14757	CHEK1	S253	P252Q	252	Missense	proximal	-1	no	8.166	7.895	EPSD	ICGC	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q9HAW4	CLSPN	O14757	CHEK1	S253	H247N	247	Missense	distal	-6	no	8.166	8.177	EPSD	ICGC	5.604	Up-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q9HAW4	CLSPN	O14757	CHEK1	S921	F919L	919	Missense	proximal	-2	no	9.563	9.379	EPSD	ICGC	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q9HAW4	CLSPN	O14757	CHEK1	S1156	D1155G	1155	Missense	proximal	-1	no	8.978	9.026	EPSD	ICGC	5.604	Up-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q9HAW4	CLSPN	O14757	CHEK1	S1223	P1225S	1225	Missense	proximal	2	no	9.247	9.324	EPSD	ICGC	5.604	Up-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q9HAW4	CLSPN	O14757	CHEK1	S1246	S1246C	1246	Missense	central	0	yes	7.155	0.000	EPSD	ICGC;COSMIC	5.604	Loss
CAMK_CAMKL_CHK1_CHEK1_ST	Q9HAW4	CLSPN	O14757	CHEK1	S1246	A1241S	1241	Missense	distal	-5	no	7.155	9.884	EPSD	ICGC	5.604	Up-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q14738	PPP2R5D	O14757	CHEK1	S88	V81F	81	Missense	distal	-7	no	8.975	7.449	EPSD	ICGC	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	P55039	DRG2	O14757	CHEK1	S72	P71L	71	Missense	proximal	-1	no	5.814	5.628	PhosphoSitePlus	ICGC;COSMIC;CCLE	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	P15822	HIVEP1	O14757	CHEK1	S148	D152Y	152	Missense	distal	4	no	9.483	9.607	EPSD	ICGC	5.604	Up-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	P15822	HIVEP1	O14757	CHEK1	S148	R144C	144	Missense	distal	-4	no	9.483	9.109	EPSD	ICGC;COSMIC	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	P15822	HIVEP1	O14757	CHEK1	S215	P216L	216	Missense	proximal	1	no	5.977	6.005	EPSD	ICGC	5.604	Up-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	P15822	HIVEP1	O14757	CHEK1	S577	K579N	579	Missense	proximal	2	no	9.026	8.618	EPSD	ICGC;COSMIC	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	P15822	HIVEP1	O14757	CHEK1	S577	K584N	584	Missense	distal	7	no	9.026	9.088	EPSD	ICGC;COSMIC	5.604	Up-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	P15822	HIVEP1	O14757	CHEK1	S577	V570M	570	Missense	distal	-7	no	9.026	8.832	EPSD	ICGC;COSMIC	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	P15822	HIVEP1	O14757	CHEK1	S681	A682S	682	Missense	proximal	1	no	9.543	9.525	EPSD	ICGC	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	P15822	HIVEP1	O14757	CHEK1	S681	V686L	686	Missense	distal	5	no	9.543	9.384	EPSD	ICGC	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	P15822	HIVEP1	O14757	CHEK1	S698	T699A	699	Missense	proximal	1	no	7.030	7.041	EPSD	ICGC;COSMIC	5.604	Up-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	P15822	HIVEP1	O14757	CHEK1	S698	R705M	705	Missense	distal	7	no	7.030	6.922	EPSD	ICGC;COSMIC	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	P15822	HIVEP1	O14757	CHEK1	S698	R694I	694	Missense	distal	-4	no	7.030	6.743	EPSD	ICGC;COSMIC	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	P15822	HIVEP1	O14757	CHEK1	S779	S773L	773	Missense	distal	-6	no	10.293	10.318	EPSD	ICGC;COSMIC	5.604	Up-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	P15822	HIVEP1	O14757	CHEK1	S779	L774P	774	Missense	distal	-5	no	10.293	5.587	EPSD	ICGC;COSMIC	5.604	Loss
CAMK_CAMKL_CHK1_CHEK1_ST	P15822	HIVEP1	O14757	CHEK1	S779	D781H	781	Missense	proximal	2	no	10.293	9.750	EPSD	ICGC	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	P15822	HIVEP1	O14757	CHEK1	S779	G778E	778	Missense	proximal	-1	no	10.293	10.186	EPSD	ICGC;COSMIC	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	P15822	HIVEP1	O14757	CHEK1	S804	D808N	808	Missense	distal	4	no	10.048	10.017	EPSD	ICGC;COSMIC	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	P15822	HIVEP1	O14757	CHEK1	S805	D808N	808	Missense	distal	3	no	9.547	8.831	EPSD	ICGC;COSMIC	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	P15822	HIVEP1	O14757	CHEK1	S841	L834S	834	Missense	distal	-7	no	6.547	7.431	EPSD	ICGC;COSMIC	5.604	Up-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	P15822	HIVEP1	O14757	CHEK1	S866	T873A	873	Missense	distal	7	no	7.550	7.666	EPSD	ICGC	5.604	Up-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	P15822	HIVEP1	O14757	CHEK1	S866	Q865H	865	Missense	proximal	-1	no	7.550	7.660	EPSD	ICGC;COSMIC	5.604	Up-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	P15822	HIVEP1	O14757	CHEK1	S866	R862K	862	Missense	distal	-4	no	7.550	7.651	EPSD	ICGC;COSMIC;GDSC;CCLE	5.604	Up-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	P15822	HIVEP1	O14757	CHEK1	T1131	H1129Q	1129	Missense	proximal	-2	no	8.209	8.191	EPSD	ICGC;COSMIC	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	P15822	HIVEP1	O14757	CHEK1	S1147	L1142M	1142	Missense	distal	-5	no	12.535	8.162	EPSD	ICGC;COSMIC	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	P15822	HIVEP1	O14757	CHEK1	S1147	R1144M	1144	Missense	distal	-3	no	12.535	7.386	EPSD	ICGC	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	P15822	HIVEP1	O14757	CHEK1	T1274	T1268S	1268	Missense	distal	-6	no	5.923	5.853	EPSD	ICGC;COSMIC	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	P15822	HIVEP1	O14757	CHEK1	S1952	Y1946F	1946	Missense	distal	-6	no	11.395	11.507	EPSD	ICGC	5.604	Up-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	P15822	HIVEP1	O14757	CHEK1	S1952	S1952L	1952	Missense	central	0	yes	11.395	0.000	EPSD	ICGC;COSMIC	5.604	Loss
CAMK_CAMKL_CHK1_CHEK1_ST	P15822	HIVEP1	O14757	CHEK1	S2101	L2103S	2103	Missense	proximal	2	no	5.982	6.377	EPSD	ICGC	5.604	Up-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	P15822	HIVEP1	O14757	CHEK1	S2101	S2101N	2101	Missense	central	0	yes	5.982	0.000	EPSD	ICGC;COSMIC	5.604	Loss
CAMK_CAMKL_CHK1_CHEK1_ST	P15822	HIVEP1	O14757	CHEK1	S2101	R2108L	2108	Missense	distal	7	no	5.982	5.882	EPSD	ICGC	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	P15822	HIVEP1	O14757	CHEK1	S2273	T2271A	2271	Missense	proximal	-2	no	7.067	6.928	EPSD	ICGC;COSMIC;GDSC;CCLE	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	P15822	HIVEP1	O14757	CHEK1	S2273	N2268S	2268	Missense	distal	-5	no	7.067	6.574	EPSD	ICGC;COSMIC	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	P15822	HIVEP1	O14757	CHEK1	S2273	P2274T	2274	Missense	proximal	1	no	7.067	7.112	EPSD	ICGC;COSMIC	5.604	Up-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	P15822	HIVEP1	O14757	CHEK1	S2273	G2275R	2275	Missense	proximal	2	no	7.067	7.037	EPSD	ICGC;COSMIC	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	P15822	HIVEP1	O14757	CHEK1	S2273	L2272F	2272	Missense	proximal	-1	no	7.067	7.081	EPSD	ICGC;COSMIC	5.604	Up-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	P15822	HIVEP1	O14757	CHEK1	S2273	R2280C	2280	Missense	distal	7	no	7.067	6.662	EPSD	ICGC	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	P15822	HIVEP1	O14757	CHEK1	S2303	P2298L	2298	Missense	distal	-5	no	2.003	6.710	EPSD	ICGC;COSMIC	5.604	Gain
CAMK_CAMKL_CHK1_CHEK1_ST	P15822	HIVEP1	O14757	CHEK1	S2587	S2590N	2590	Missense	distal	3	no	5.144	5.985	EPSD	ICGC;COSMIC	5.604	Gain
CAMK_CAMKL_CHK1_CHEK1_ST	Q9HB96	FANCE	O14757	CHEK1	S180	G175S	175	Missense	distal	-5	no	9.078	9.032	EPSD	ICGC	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q9HB96	FANCE	O14757	CHEK1	S204	E207K	207	Missense	distal	3	no	8.434	7.618	EPSD	ICGC	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q9HB96	FANCE	O14757	CHEK1	S204	D203Y	203	Missense	proximal	-1	no	8.434	8.633	EPSD	ICGC	5.604	Up-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q9HB96	FANCE	O14757	CHEK1	T346	R343Q	343	Missense	distal	-3	no	9.035	1.829	PhosphoSitePlus;EPSD	ICGC	5.604	Loss
CAMK_CAMKL_CHK1_CHEK1_ST	Q9HB96	FANCE	O14757	CHEK1	T346	C345R	345	Missense	proximal	-1	no	9.035	9.001	PhosphoSitePlus;EPSD	ICGC	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q9HB96	FANCE	O14757	CHEK1	T346	T346N	346	Missense	central	0	yes	9.035	0.000	PhosphoSitePlus;EPSD	ICGC	5.604	Loss
CAMK_CAMKL_CHK1_CHEK1_ST	Q9HB96	FANCE	O14757	CHEK1	S374	I372V	372	Missense	proximal	-2	no	14.596	14.659	EPSD;PhosphoSitePlus	ICGC;COSMIC	5.604	Up-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q9HB96	FANCE	O14757	CHEK1	S374	R381C	381	Missense	distal	7	no	14.596	14.190	EPSD;PhosphoSitePlus	ICGC;COSMIC	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q96QD9	FYTTD1	O14757	CHEK1	T6	R3W	3	Missense	distal	-3	no	7.471	-26.133	EPSD	ICGC;COSMIC	5.604	Loss
CAMK_CAMKL_CHK1_CHEK1_ST	P06493	CDK1	O14757	CHEK1	S39	P45S	45	Missense	distal	6	no	12.639	12.020	EPSD	ICGC	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	P06493	CDK1	O14757	CHEK1	S53	R59H	59	Missense	distal	6	no	5.802	6.090	EPSD	ICGC;COSMIC	5.604	Up-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	P06493	CDK1	O14757	CHEK1	S53	R50L	50	Missense	distal	-3	no	5.802	-12.745	EPSD	ICGC;COSMIC	5.604	Loss
CAMK_CAMKL_CHK1_CHEK1_ST	P06493	CDK1	O14757	CHEK1	T183	R180C	180	Missense	distal	-3	no	7.979	-0.112	EPSD	ICGC	5.604	Loss
CAMK_CAMKL_CHK1_CHEK1_ST	P06493	CDK1	O14757	CHEK1	T183	P184Q	184	Missense	proximal	1	no	7.979	8.051	EPSD	ICGC;COSMIC	5.604	Up-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	P06493	CDK1	O14757	CHEK1	S208	G206R	206	Missense	proximal	-2	no	9.309	9.276	PhosphoSitePlus	ICGC	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	P06493	CDK1	O14757	CHEK1	S208	P202Q	202	Missense	distal	-6	no	9.309	9.214	PhosphoSitePlus	ICGC;COSMIC	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q9BY77	POLDIP3	O14757	CHEK1	S127	P128S	128	Missense	proximal	1	no	7.112	7.148	EPSD	ICGC;GDSC;CCLE	5.604	Up-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q9BY77	POLDIP3	O14757	CHEK1	T256	T256K	256	Missense	central	0	yes	7.393	0.000	EPSD	ICGC;COSMIC	5.604	Loss
CAMK_CAMKL_CHK1_CHEK1_ST	Q9BY77	POLDIP3	O14757	CHEK1	S383	P390S	390	Missense	distal	7	no	9.236	9.180	EPSD	ICGC	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	P26373	RPL13	O14757	CHEK1	S52	R45H	45	Missense	distal	-7	no	8.235	8.175	EPSD	ICGC;COSMIC	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	P26373	RPL13	O14757	CHEK1	S52	R56W	56	Missense	distal	4	no	8.235	8.298	EPSD	ICGC;COSMIC	5.604	Up-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	P26373	RPL13	O14757	CHEK1	S77	L81F	81	Missense	distal	4	no	9.940	10.001	EPSD	ICGC;COSMIC	5.604	Up-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	P26373	RPL13	O14757	CHEK1	S77	A72T	72	Missense	distal	-5	no	9.940	13.800	EPSD	ICGC;COSMIC	5.604	Up-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	P26373	RPL13	O14757	CHEK1	S122	E119K	119	Missense	distal	-3	no	2.951	6.214	EPSD	ICGC;COSMIC	5.604	Gain
CAMK_CAMKL_CHK1_CHEK1_ST	P26373	RPL13	O14757	CHEK1	T170	R167G	167	Missense	distal	-3	no	14.182	6.407	PhosphoSitePlus	ICGC	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	P18858	LIG1	O14757	CHEK1	T97	R94H	94	Missense	distal	-3	no	6.890	1.081	EPSD	ICGC;COSMIC	5.604	Loss
CAMK_CAMKL_CHK1_CHEK1_ST	P18858	LIG1	O14757	CHEK1	S552	E553K	553	Missense	proximal	1	no	7.927	7.853	EPSD	ICGC;COSMIC	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	P43405	SYK	O14757	CHEK1	S93	V100I	100	Missense	distal	7	no	7.128	6.707	EPSD	ICGC;COSMIC	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	P43405	SYK	O14757	CHEK1	S178	R175W	175	Missense	distal	-3	no	8.923	-24.680	EPSD	ICGC;COSMIC	5.604	Loss
CAMK_CAMKL_CHK1_CHEK1_ST	P43405	SYK	O14757	CHEK1	T256	V257F	257	Missense	proximal	1	no	8.766	8.768	EPSD	ICGC	5.604	Up-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	P43405	SYK	O14757	CHEK1	T256	C259F	259	Missense	distal	3	no	8.766	9.904	EPSD	ICGC;COSMIC	5.604	Up-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	P43405	SYK	O14757	CHEK1	T256	D249N	249	Missense	distal	-7	no	8.766	8.459	EPSD	ICGC	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	P43405	SYK	O14757	CHEK1	S295	P299L	299	Missense	distal	4	no	11.476	11.373	PhosphoSitePlus	ICGC;COSMIC	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	P43405	SYK	O14757	CHEK1	S295	G302D	302	Missense	distal	7	no	11.476	11.769	PhosphoSitePlus	ICGC;COSMIC	5.604	Up-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	P43405	SYK	O14757	CHEK1	S295	P299S	299	Missense	distal	4	no	11.476	11.336	PhosphoSitePlus	ICGC;COSMIC	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	P43405	SYK	O14757	CHEK1	S297	P299L	299	Missense	proximal	2	no	5.822	5.504	EPSD	ICGC;COSMIC	5.604	Loss
CAMK_CAMKL_CHK1_CHEK1_ST	P43405	SYK	O14757	CHEK1	S297	G302D	302	Missense	distal	5	no	5.822	6.100	EPSD	ICGC;COSMIC	5.604	Up-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	P43405	SYK	O14757	CHEK1	S297	P299S	299	Missense	proximal	2	no	5.822	5.898	EPSD	ICGC;COSMIC	5.604	Up-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	P43405	SYK	O14757	CHEK1	S297	H303N	303	Missense	distal	6	no	5.822	5.580	EPSD	ICGC;COSMIC	5.604	Loss
CAMK_CAMKL_CHK1_CHEK1_ST	P43405	SYK	O14757	CHEK1	S307	K305R	305	Missense	proximal	-2	no	12.325	12.506	EPSD	ICGC	5.604	Up-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	P43405	SYK	O14757	CHEK1	S307	G302D	302	Missense	distal	-5	no	12.325	11.503	EPSD	ICGC;COSMIC	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	P43405	SYK	O14757	CHEK1	S307	H303N	303	Missense	distal	-4	no	12.325	12.508	EPSD	ICGC;COSMIC	5.604	Up-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	P52294	KPNA1	O14757	CHEK1	S13	N16K	16	Missense	distal	3	no	10.253	10.056	EPSD	ICGC	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	P52294	KPNA1	O14757	CHEK1	S221	N224K	224	Missense	distal	3	no	7.413	7.216	EPSD	ICGC	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	P52294	KPNA1	O14757	CHEK1	S244	L239I	239	Missense	distal	-5	no	13.709	11.678	EPSD	ICGC;COSMIC	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q8N4C8	MINK1	O14757	CHEK1	T59	I66M	66	Missense	distal	7	no	5.783	6.060	EPSD	ICGC;COSMIC	5.604	Up-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q8N4C8	MINK1	O14757	CHEK1	T187	R184I	184	Missense	distal	-3	no	8.698	-0.060	EPSD	ICGC	5.604	Loss
CAMK_CAMKL_CHK1_CHEK1_ST	Q8N4C8	MINK1	O14757	CHEK1	T280	L275M	275	Missense	distal	-5	no	11.652	7.279	PhosphoSitePlus	ICGC;COSMIC	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q8N4C8	MINK1	O14757	CHEK1	S544	I551T	551	Missense	distal	7	no	7.762	7.987	EPSD	ICGC;COSMIC	5.604	Up-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q8N4C8	MINK1	O14757	CHEK1	S601	R598L	598	Missense	distal	-3	no	11.420	-7.127	EPSD	ICGC	5.604	Loss
CAMK_CAMKL_CHK1_CHEK1_ST	Q8N4C8	MINK1	O14757	CHEK1	S641	G647A	647	Missense	distal	6	no	9.572	9.748	EPSD	ICGC;COSMIC	5.604	Up-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q8N4C8	MINK1	O14757	CHEK1	S641	R638L	638	Missense	distal	-3	no	9.572	-8.975	EPSD	ICGC;COSMIC	5.604	Loss
CAMK_CAMKL_CHK1_CHEK1_ST	Q8N4C8	MINK1	O14757	CHEK1	S674	T672A	672	Missense	proximal	-2	no	10.421	10.282	EPSD	ICGC;COSMIC;GDSC;CCLE	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q8N4C8	MINK1	O14757	CHEK1	S749	E745Q	745	Missense	distal	-4	no	8.314	8.271	EPSD	ICGC;COSMIC	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q8N4C8	MINK1	O14757	CHEK1	S903	H900R	900	Missense	distal	-3	no	5.915	11.725	EPSD	ICGC	5.604	Up-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q8N4C8	MINK1	O14757	CHEK1	S993	V997L	997	Missense	distal	4	no	10.038	9.963	EPSD	ICGC;COSMIC	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	P30307	CDC25C	O14757	CHEK1	S38	L33P	33	Missense	distal	-5	no	10.974	6.267	EPSD	ICGC;COSMIC	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	P30307	CDC25C	O14757	CHEK1	S216	E219D	219	Missense	distal	3	no	12.705	12.803	PhosphoSitePlus	ICGC;COSMIC	5.604	Up-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	P30307	CDC25C	O14757	CHEK1	T236	D239N	239	Missense	distal	3	no	5.722	5.006	EPSD	ICGC	5.604	Loss
CAMK_CAMKL_CHK1_CHEK1_ST	P30307	CDC25C	O14757	CHEK1	T236	N235S	235	Missense	proximal	-1	no	5.722	5.504	EPSD	ICGC	5.604	Loss
CAMK_CAMKL_CHK1_CHEK1_ST	P30307	CDC25C	O14757	CHEK1	S449	G456V	456	Missense	distal	7	no	9.931	9.961	EPSD	ICGC;COSMIC	5.604	Up-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	P30307	CDC25C	O14757	CHEK1	S451	G456V	456	Missense	distal	5	no	6.936	7.042	EPSD	ICGC;COSMIC	5.604	Up-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q02750	MAP2K1	O14757	CHEK1	T55	F53C	53	Missense	proximal	-2	no	7.717	7.475	PhosphoSitePlus	ICGC;COSMIC	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q02750	MAP2K1	O14757	CHEK1	T292	P288H	288	Missense	distal	-4	no	5.758	5.632	EPSD	ICGC;COSMIC	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q02750	MAP2K1	O14757	CHEK1	T292	G294W	294	Missense	proximal	2	no	5.758	5.553	EPSD	ICGC;COSMIC	5.604	Loss
CAMK_CAMKL_CHK1_CHEK1_ST	Q02750	MAP2K1	O14757	CHEK1	T292	P296H	296	Missense	distal	4	no	5.758	5.830	EPSD	ICGC;COSMIC	5.604	Up-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q02750	MAP2K1	O14757	CHEK1	S298	G294W	294	Missense	distal	-4	no	7.076	6.288	EPSD	ICGC;COSMIC	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q02750	MAP2K1	O14757	CHEK1	S298	P296H	296	Missense	proximal	-2	no	7.076	6.956	EPSD	ICGC;COSMIC	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	P06400	RB1	O14757	CHEK1	S83	D85H	85	Missense	proximal	2	no	6.116	5.573	EPSD	ICGC;COSMIC	5.604	Loss
CAMK_CAMKL_CHK1_CHEK1_ST	P06400	RB1	O14757	CHEK1	S83	E79K	79	Missense	distal	-4	no	6.116	6.014	EPSD	ICGC;COSMIC	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	P06400	RB1	O14757	CHEK1	S83	V81F	81	Missense	proximal	-2	no	6.116	6.214	EPSD	ICGC	5.604	Up-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	P06400	RB1	O14757	CHEK1	S83	G86V	86	Missense	distal	3	no	6.116	6.542	EPSD	ICGC	5.604	Up-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	P06400	RB1	O14757	CHEK1	S83	G90V	90	Missense	distal	7	no	6.116	6.146	EPSD	ICGC	5.604	Up-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	P06400	RB1	O14757	CHEK1	S163	C169Y	169	Missense	distal	6	no	7.685	8.045	EPSD	ICGC;COSMIC;CCLE	5.604	Up-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	P06400	RB1	O14757	CHEK1	T766	R763T	763	Missense	distal	-3	no	5.906	-14.663	EPSD	ICGC;COSMIC	5.604	Loss
CAMK_CAMKL_CHK1_CHEK1_ST	P06400	RB1	O14757	CHEK1	T778	P783L	783	Missense	distal	5	no	7.192	7.031	EPSD	ICGC	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	P19838	NFKB1	O14757	CHEK1	S328	Q332E	332	Missense	distal	4	no	8.043	7.952	PhosphoSitePlus	ICGC	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	P19838	NFKB1	O14757	CHEK1	S328	R334Q	334	Missense	distal	6	no	8.043	8.037	PhosphoSitePlus	ICGC;COSMIC	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	P19838	NFKB1	O14757	CHEK1	S328	K325N	325	Missense	distal	-3	no	8.043	1.501	PhosphoSitePlus	ICGC;COSMIC	5.604	Loss
CAMK_CAMKL_CHK1_CHEK1_ST	P19838	NFKB1	O14757	CHEK1	S328	R334W	334	Missense	distal	6	no	8.043	8.510	PhosphoSitePlus	ICGC;COSMIC	5.604	Up-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	P19838	NFKB1	O14757	CHEK1	S328	I321V	321	Missense	distal	-7	no	8.043	8.480	PhosphoSitePlus	ICGC;COSMIC	5.604	Up-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	P19838	NFKB1	O14757	CHEK1	S328	I323S	323	Missense	distal	-5	no	8.043	6.887	PhosphoSitePlus	ICGC	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	P19838	NFKB1	O14757	CHEK1	S337	Q332E	332	Missense	distal	-5	no	7.660	6.670	EPSD	ICGC	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	P19838	NFKB1	O14757	CHEK1	S337	R334Q	334	Missense	distal	-3	no	7.660	0.453	EPSD	ICGC;COSMIC	5.604	Loss
CAMK_CAMKL_CHK1_CHEK1_ST	P19838	NFKB1	O14757	CHEK1	S337	R334W	334	Missense	distal	-3	no	7.660	-25.943	EPSD	ICGC;COSMIC	5.604	Loss
CAMK_CAMKL_CHK1_CHEK1_ST	P19838	NFKB1	O14757	CHEK1	S899	S892F	892	Missense	distal	-7	no	7.058	5.326	EPSD	ICGC;COSMIC	5.604	Loss
CAMK_CAMKL_CHK1_CHEK1_ST	P19838	NFKB1	O14757	CHEK1	S899	Q900E	900	Missense	proximal	1	no	7.058	7.123	EPSD	ICGC;COSMIC	5.604	Up-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	P19838	NFKB1	O14757	CHEK1	S899	S892Y	892	Missense	distal	-7	no	7.058	5.399	EPSD	ICGC;COSMIC	5.604	Loss
CAMK_CAMKL_CHK1_CHEK1_ST	P19838	NFKB1	O14757	CHEK1	S899	S892P	892	Missense	distal	-7	no	7.058	6.388	EPSD	ICGC;COSMIC	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	P19838	NFKB1	O14757	CHEK1	S899	A901D	901	Missense	proximal	2	no	7.058	7.068	EPSD	ICGC;COSMIC	5.604	Up-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	P19838	NFKB1	O14757	CHEK1	S899	P894L	894	Missense	distal	-5	no	7.058	11.764	EPSD	ICGC	5.604	Up-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	P19838	NFKB1	O14757	CHEK1	S937	R934L	934	Missense	distal	-3	no	9.519	-9.028	EPSD	ICGC	5.604	Loss
CAMK_CAMKL_CHK1_CHEK1_ST	P19838	NFKB1	O14757	CHEK1	S937	S944R	944	Missense	distal	7	no	9.519	9.612	EPSD	ICGC	5.604	Up-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	P19838	NFKB1	O14757	CHEK1	S937	R934C	934	Missense	distal	-3	no	9.519	1.428	EPSD	ICGC;COSMIC	5.604	Loss
CAMK_CAMKL_CHK1_CHEK1_ST	P19838	NFKB1	O14757	CHEK1	S947	S944R	944	Missense	distal	-3	no	0.822	10.518	EPSD	ICGC	5.604	Gain
CAMK_CAMKL_CHK1_CHEK1_ST	Q9BXB4	OSBPL11	O14757	CHEK1	S48	Y54H	54	Missense	distal	6	no	10.060	9.694	EPSD	ICGC;COSMIC	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q9BXB4	OSBPL11	O14757	CHEK1	S170	P166L	166	Missense	distal	-4	no	5.967	5.782	EPSD	ICGC	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q9BXB4	OSBPL11	O14757	CHEK1	S189	F195V	195	Missense	distal	6	no	9.297	9.171	PhosphoSitePlus	ICGC	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q9BXB4	OSBPL11	O14757	CHEK1	S189	A192V	192	Missense	distal	3	no	9.297	9.542	PhosphoSitePlus	ICGC;COSMIC	5.604	Up-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q96RL1	UIMC1	O14757	CHEK1	S12	S14Y	14	Missense	proximal	2	no	7.956	7.659	EPSD	ICGC;COSMIC	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q96RL1	UIMC1	O14757	CHEK1	S330	P328H	328	Missense	proximal	-2	no	11.430	11.309	EPSD	ICGC	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q96RL1	UIMC1	O14757	CHEK1	S463	E461D	461	Missense	proximal	-2	no	10.592	10.578	EPSD	ICGC;COSMIC	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q96RL1	UIMC1	O14757	CHEK1	S463	S463A	463	Missense	central	0	yes	10.592	0.000	EPSD	ICGC	5.604	Loss
CAMK_CAMKL_CHK1_CHEK1_ST	Q96ST3	SIN3A	O14757	CHEK1	S139	Q132H	132	Missense	distal	-7	no	5.638	5.321	EPSD	ICGC;COSMIC	5.604	Loss
CAMK_CAMKL_CHK1_CHEK1_ST	Q96ST3	SIN3A	O14757	CHEK1	S139	L135P	135	Missense	distal	-4	no	5.638	5.822	EPSD	ICGC;COSMIC	5.604	Up-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q96ST3	SIN3A	O14757	CHEK1	T432	P437Q	437	Missense	distal	5	no	9.233	9.287	EPSD	ICGC	5.604	Up-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q96ST3	SIN3A	O14757	CHEK1	S451	M452R	452	Missense	proximal	1	no	7.803	7.843	EPSD	ICGC;COSMIC	5.604	Up-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q96ST3	SIN3A	O14757	CHEK1	S451	S456R	456	Missense	distal	5	no	7.803	7.700	EPSD	ICGC	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q96ST3	SIN3A	O14757	CHEK1	S451	D454Y	454	Missense	distal	3	no	7.803	5.018	EPSD	ICGC	5.604	Loss
CAMK_CAMKL_CHK1_CHEK1_ST	Q96ST3	SIN3A	O14757	CHEK1	S641	R642H	642	Missense	proximal	1	no	6.078	6.012	EPSD	ICGC;COSMIC	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q96ST3	SIN3A	O14757	CHEK1	S641	L640R	640	Missense	proximal	-1	no	6.078	5.978	EPSD	ICGC;COSMIC	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q96ST3	SIN3A	O14757	CHEK1	S641	Q648K	648	Missense	distal	7	no	6.078	5.998	EPSD	ICGC	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q96ST3	SIN3A	O14757	CHEK1	S748	S748G	748	Missense	central	0	yes	8.244	0.000	EPSD	ICGC;COSMIC	5.604	Loss
CAMK_CAMKL_CHK1_CHEK1_ST	Q96ST3	SIN3A	O14757	CHEK1	S748	S755I	755	Missense	distal	7	no	8.244	7.952	EPSD	ICGC;COSMIC	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q96ST3	SIN3A	O14757	CHEK1	S755	S748G	748	Missense	distal	-7	no	5.642	5.421	EPSD	ICGC;COSMIC	5.604	Loss
CAMK_CAMKL_CHK1_CHEK1_ST	Q96ST3	SIN3A	O14757	CHEK1	S755	S755I	755	Missense	central	0	yes	5.642	0.000	EPSD	ICGC;COSMIC	5.604	Loss
CAMK_CAMKL_CHK1_CHEK1_ST	Q96ST3	SIN3A	O14757	CHEK1	S911	R905S	905	Missense	distal	-6	no	13.347	13.427	EPSD	ICGC;COSMIC	5.604	Up-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q96ST3	SIN3A	O14757	CHEK1	S938	L931M	931	Missense	distal	-7	no	8.201	8.685	EPSD	ICGC;COSMIC	5.604	Up-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q96ST3	SIN3A	O14757	CHEK1	T1084	L1081H	1081	Missense	distal	-3	no	-7.067	5.670	EPSD	ICGC	5.604	Gain
CAMK_CAMKL_CHK1_CHEK1_ST	Q96ST3	SIN3A	O14757	CHEK1	T1155	S1152R	1152	Missense	distal	-3	no	1.091	10.787	EPSD	ICGC	5.604	Gain
CAMK_CAMKL_CHK1_CHEK1_ST	Q13470	TNK1	O14757	CHEK1	S508	G510W	510	Missense	proximal	2	no	5.696	5.492	EPSD	ICGC;COSMIC	5.604	Loss
CAMK_CAMKL_CHK1_CHEK1_ST	Q32P44	EML3	O14757	CHEK1	S186	G185C	185	Missense	proximal	-1	no	10.618	10.636	EPSD	ICGC;COSMIC	5.604	Up-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q32P44	EML3	O14757	CHEK1	S198	P202T	202	Missense	distal	4	no	5.937	5.808	EPSD	ICGC;COSMIC	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q32P44	EML3	O14757	CHEK1	S198	P202L	202	Missense	distal	4	no	5.937	5.833	EPSD	ICGC;COSMIC	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q9Y4F5	CEP170B	O14757	CHEK1	S466	S459L	459	Missense	distal	-7	no	11.921	11.037	EPSD	ICGC;COSMIC;CCLE	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q9Y4F5	CEP170B	O14757	CHEK1	S478	A482T	482	Missense	distal	4	no	11.308	11.125	EPSD	ICGC	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q9Y4F5	CEP170B	O14757	CHEK1	S619	G623R	623	Missense	distal	4	no	7.776	7.759	EPSD	ICGC	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q9Y4F5	CEP170B	O14757	CHEK1	S636	L631P	631	Missense	distal	-5	no	6.435	1.729	EPSD	ICGC;COSMIC	5.604	Loss
CAMK_CAMKL_CHK1_CHEK1_ST	Q9Y4F5	CEP170B	O14757	CHEK1	S868	P873S	873	Missense	distal	5	no	8.373	8.455	EPSD	ICGC;COSMIC	5.604	Up-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q9Y4F5	CEP170B	O14757	CHEK1	S875	P873S	873	Missense	proximal	-2	no	6.636	6.352	EPSD	ICGC;COSMIC	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q9Y4F5	CEP170B	O14757	CHEK1	S930	A926S	926	Missense	distal	-4	no	7.980	7.601	EPSD	ICGC;COSMIC	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q9Y4F5	CEP170B	O14757	CHEK1	S1007	R1010Q	1010	Missense	distal	3	no	8.938	10.001	EPSD	ICGC;COSMIC	5.604	Up-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q9Y4F5	CEP170B	O14757	CHEK1	S1007	H1013Q	1013	Missense	distal	6	no	8.938	8.644	EPSD	ICGC;COSMIC	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q9Y4F5	CEP170B	O14757	CHEK1	S1007	S1008P	1008	Missense	proximal	1	no	8.938	8.902	EPSD	ICGC;COSMIC	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q9Y4F5	CEP170B	O14757	CHEK1	S1290	S1291G	1291	Missense	proximal	1	no	6.845	6.862	EPSD	ICGC;COSMIC	5.604	Up-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q9Y4F5	CEP170B	O14757	CHEK1	S1296	S1291G	1291	Missense	distal	-5	no	9.962	10.008	EPSD	ICGC;COSMIC	5.604	Up-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q8WWI1	LMO7	O14757	CHEK1	S56	V54F	54	Missense	proximal	-2	no	10.722	10.820	EPSD	ICGC	5.604	Up-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q8WWI1	LMO7	O14757	CHEK1	S56	R63M	63	Missense	distal	7	no	10.722	10.614	EPSD	ICGC;COSMIC	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q8WWI1	LMO7	O14757	CHEK1	T117	N113D	113	Missense	distal	-4	no	9.164	9.240	EPSD	ICGC;COSMIC	5.604	Up-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q8WWI1	LMO7	O14757	CHEK1	T117	N113S	113	Missense	distal	-4	no	9.164	8.870	EPSD	ICGC;COSMIC	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q8WWI1	LMO7	O14757	CHEK1	S246	K242N	242	Missense	distal	-4	no	8.531	8.417	EPSD	ICGC	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q8WWI1	LMO7	O14757	CHEK1	S322	L328F	328	Missense	distal	6	no	11.502	11.495	EPSD	ICGC;COSMIC	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q8WWI1	LMO7	O14757	CHEK1	S407	K405N	405	Missense	proximal	-2	no	8.258	8.529	EPSD	ICGC	5.604	Up-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q8WWI1	LMO7	O14757	CHEK1	S407	R404C	404	Missense	distal	-3	no	8.258	0.167	EPSD	ICGC	5.604	Loss
CAMK_CAMKL_CHK1_CHEK1_ST	Q8WWI1	LMO7	O14757	CHEK1	S407	L401I	401	Missense	distal	-6	no	8.258	8.233	EPSD	ICGC	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q8WWI1	LMO7	O14757	CHEK1	T485	R486C	486	Missense	proximal	1	no	7.614	7.604	EPSD	ICGC	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q8WWI1	LMO7	O14757	CHEK1	T485	L490R	490	Missense	distal	5	no	7.614	7.754	EPSD	ICGC	5.604	Up-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q8WWI1	LMO7	O14757	CHEK1	T485	R486H	486	Missense	proximal	1	no	7.614	7.548	EPSD	ICGC	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q8WWI1	LMO7	O14757	CHEK1	S540	F539L	539	Missense	proximal	-1	no	8.736	8.722	EPSD	ICGC	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q8WWI1	LMO7	O14757	CHEK1	S540	D543N	543	Missense	distal	3	no	8.736	8.019	EPSD	ICGC	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q8WWI1	LMO7	O14757	CHEK1	S751	R749Q	749	Missense	proximal	-2	no	7.402	7.448	EPSD	ICGC	5.604	Up-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q8WWI1	LMO7	O14757	CHEK1	S751	D747N	747	Missense	distal	-4	no	7.402	7.326	EPSD	ICGC	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q8WWI1	LMO7	O14757	CHEK1	S751	R748K	748	Missense	distal	-3	no	7.402	3.577	EPSD	ICGC;COSMIC	5.604	Loss
CAMK_CAMKL_CHK1_CHEK1_ST	Q8WWI1	LMO7	O14757	CHEK1	T818	E823Q	823	Missense	distal	5	no	9.464	9.351	EPSD	ICGC	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q8WWI1	LMO7	O14757	CHEK1	T818	R815Q	815	Missense	distal	-3	no	9.464	2.257	EPSD	ICGC	5.604	Loss
CAMK_CAMKL_CHK1_CHEK1_ST	Q8WWI1	LMO7	O14757	CHEK1	S884	S878Y	878	Missense	distal	-6	no	6.625	6.786	EPSD	ICGC;COSMIC	5.604	Up-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q8WWI1	LMO7	O14757	CHEK1	S884	R891C	891	Missense	distal	7	no	6.625	6.219	EPSD	ICGC	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q8WWI1	LMO7	O14757	CHEK1	S910	D904N	904	Missense	distal	-6	no	9.994	10.207	EPSD	ICGC	5.604	Up-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q8WWI1	LMO7	O14757	CHEK1	S910	P916S	916	Missense	distal	6	no	9.994	9.374	EPSD	ICGC	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q8WWI1	LMO7	O14757	CHEK1	S925	S930P	930	Missense	distal	5	no	8.062	7.980	EPSD	ICGC	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q8WWI1	LMO7	O14757	CHEK1	S925	P928Q	928	Missense	distal	3	no	8.062	8.793	EPSD	ICGC;COSMIC	5.604	Up-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q8WWI1	LMO7	O14757	CHEK1	S925	R922S	922	Missense	distal	-3	no	8.062	-1.634	EPSD	ICGC	5.604	Loss
CAMK_CAMKL_CHK1_CHEK1_ST	Q8WWI1	LMO7	O14757	CHEK1	T932	S930P	930	Missense	proximal	-2	no	12.357	12.641	EPSD	ICGC	5.604	Up-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q8WWI1	LMO7	O14757	CHEK1	T932	M933V	933	Missense	proximal	1	no	12.357	12.365	EPSD	ICGC	5.604	Up-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q8WWI1	LMO7	O14757	CHEK1	T932	P928Q	928	Missense	distal	-4	no	12.357	12.589	EPSD	ICGC;COSMIC	5.604	Up-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q8WWI1	LMO7	O14757	CHEK1	S1032	Q1035H	1035	Missense	distal	3	no	7.794	6.762	EPSD	ICGC	5.604	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q9Y6W5	WASF2	P27361	MAPK3	T129	P131S	131	Missense	proximal	2	no	13.089	13.091	EPSD	ICGC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q9Y6W5	WASF2	P27361	MAPK3	T137	P131S	131	Missense	distal	-6	no	14.841	14.925	EPSD	ICGC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q9Y6W5	WASF2	P27361	MAPK3	S257	P250S	250	Missense	distal	-7	no	16.804	16.766	EPSD	ICGC;COSMIC;CCLE	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q9Y6W5	WASF2	P27361	MAPK3	S259	N266T	266	Missense	distal	7	no	16.799	16.751	EPSD	ICGC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q9Y6W5	WASF2	P27361	MAPK3	S296	H299R	299	Missense	distal	3	no	16.695	16.687	EPSD	ICGC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q9Y6W5	WASF2	P27361	MAPK3	S296	P301T	301	Missense	distal	5	no	16.695	16.602	EPSD	ICGC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q9Y6W5	WASF2	P27361	MAPK3	S308	P301T	301	Missense	distal	-7	no	17.128	17.167	EPSD	ICGC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q9Y6W5	WASF2	P27361	MAPK3	S308	G311C	311	Missense	distal	3	no	17.128	17.058	EPSD	ICGC;COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q9Y6W5	WASF2	P27361	MAPK3	S343	P348L	348	Missense	distal	5	no	15.818	15.591	EPSD;PhosphoSitePlus	ICGC;COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q9Y6W5	WASF2	P27361	MAPK3	S343	P337L	337	Missense	distal	-6	no	15.818	15.571	EPSD;PhosphoSitePlus	ICGC;CCLE	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q9Y6W5	WASF2	P27361	MAPK3	T346	P348L	348	Missense	proximal	2	no	17.447	17.425	EPSD;PhosphoSitePlus	ICGC;COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q9Y6W5	WASF2	P27361	MAPK3	S351	P348L	348	Missense	distal	-3	no	17.575	17.491	PhosphoSitePlus;EPSD	ICGC;COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q9Y6W5	WASF2	P27361	MAPK3	S351	H358Q	358	Missense	distal	7	no	17.575	17.638	PhosphoSitePlus;EPSD	ICGC;COSMIC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q9Y6W5	WASF2	P27361	MAPK3	S484	Y481F	481	Missense	distal	-3	no	11.190	11.112	EPSD	ICGC;COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P11388	TOP2A	P27361	MAPK3	S4	P8S	8	Missense	distal	4	no	14.357	14.406	EPSD	ICGC;COSMIC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P11388	TOP2A	P27361	MAPK3	S387	Q393K	393	Missense	distal	6	no	12.402	12.505	EPSD	ICGC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P11388	TOP2A	P27361	MAPK3	S802	A801D	801	Missense	proximal	-1	no	16.067	16.154	EPSD	ICGC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P11388	TOP2A	P27361	MAPK3	T950	M943T	943	Missense	distal	-7	no	16.507	16.378	EPSD	ICGC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P11388	TOP2A	P27361	MAPK3	S1115	G1122E	1122	Missense	distal	7	no	11.365	11.330	EPSD	ICGC;COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P11388	TOP2A	P27361	MAPK3	S1115	E1109K	1109	Missense	distal	-6	no	11.365	11.223	EPSD	ICGC;COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P11388	TOP2A	P27361	MAPK3	T1124	P1123Q	1123	Missense	proximal	-1	no	9.508	9.422	EPSD	ICGC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P11388	TOP2A	P27361	MAPK3	T1124	G1122E	1122	Missense	proximal	-2	no	9.508	9.978	EPSD	ICGC;COSMIC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P11388	TOP2A	P27361	MAPK3	S1162	L1166F	1166	Missense	distal	4	no	17.955	17.744	EPSD	ICGC;COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P11388	TOP2A	P27361	MAPK3	S1162	P1163L	1163	Missense	proximal	1	no	17.955	8.917	EPSD	ICGC	9.358	Loss
CMGC_MAPK_ERK1_MAPK3_ST	P11388	TOP2A	P27361	MAPK3	S1354	P1355S	1355	Missense	proximal	1	no	16.824	7.770	EPSD;PhosphoSitePlus	ICGC	9.358	Loss
CMGC_MAPK_ERK1_MAPK3_ST	P11388	TOP2A	P27361	MAPK3	S1354	P1350T	1350	Missense	distal	-4	no	16.824	16.793	EPSD;PhosphoSitePlus	ICGC;COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P11388	TOP2A	P27361	MAPK3	S1361	P1355S	1355	Missense	distal	-6	no	15.263	15.348	PhosphoSitePlus;EPSD	ICGC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P11388	TOP2A	P27361	MAPK3	S1377	V1376M	1376	Missense	proximal	-1	no	9.456	9.384	EPSD	ICGC;COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P11388	TOP2A	P27361	MAPK3	S1393	P1395T	1395	Missense	proximal	2	no	15.613	15.604	EPSD;PhosphoSitePlus	ICGC;COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P11388	TOP2A	P27361	MAPK3	S1393	P1394T	1394	Missense	proximal	1	no	15.613	6.736	EPSD;PhosphoSitePlus	ICGC;COSMIC	9.358	Loss
CMGC_MAPK_ERK1_MAPK3_ST	P11388	TOP2A	P27361	MAPK3	S1471	S1469P	1469	Missense	proximal	-2	no	8.881	9.957	EPSD	ICGC	9.358	Gain
CMGC_MAPK_ERK1_MAPK3_ST	Q07820	MCL1	P27361	MAPK3	T92	V86L	86	Missense	distal	-6	no	13.770	13.768	PhosphoSitePlus;EPSD	ICGC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q07820	MCL1	P27361	MAPK3	T92	E85D	85	Missense	distal	-7	no	13.770	13.780	PhosphoSitePlus;EPSD	ICGC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q07820	MCL1	P27361	MAPK3	T92	A94T	94	Missense	proximal	2	no	13.770	13.797	PhosphoSitePlus;EPSD	ICGC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q07820	MCL1	P27361	MAPK3	T92	R95S	95	Missense	distal	3	no	13.770	13.792	PhosphoSitePlus;EPSD	ICGC;COSMIC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q07820	MCL1	P27361	MAPK3	T92	T92P	92	Missense	central	0	yes	13.770	0.000	PhosphoSitePlus;EPSD	ICGC;COSMIC	9.358	Loss
CMGC_MAPK_ERK1_MAPK3_ST	Q07820	MCL1	P27361	MAPK3	S121	I119V	119	Missense	proximal	-2	no	14.022	14.206	EPSD	ICGC;COSMIC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q07820	MCL1	P27361	MAPK3	S121	E125D	125	Missense	distal	4	no	14.022	14.003	EPSD	ICGC;COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q07820	MCL1	P27361	MAPK3	T163	T156A	156	Missense	distal	-7	no	16.774	16.847	EPSD;PhosphoSitePlus	ICGC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q07820	MCL1	P27361	MAPK3	T163	P161S	161	Missense	proximal	-2	no	16.774	15.698	EPSD;PhosphoSitePlus	ICGC;COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q07820	MCL1	P27361	MAPK3	T163	P166Q	166	Missense	distal	3	no	16.774	16.747	EPSD;PhosphoSitePlus	ICGC;COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q07820	MCL1	P27361	MAPK3	S245	L246F	246	Missense	proximal	1	no	8.276	11.100	EPSD	ICGC;COSMIC	9.358	Gain
CMGC_MAPK_ERK1_MAPK3_ST	P15056	BRAF	P27361	MAPK3	S151	N148S	148	Missense	distal	-3	no	14.464	14.509	EPSD	ICGC;COSMIC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P15056	BRAF	P27361	MAPK3	S151	P152S	152	Missense	proximal	1	no	14.464	5.411	EPSD	ICGC;COSMIC	9.358	Loss
CMGC_MAPK_ERK1_MAPK3_ST	P15056	BRAF	P27361	MAPK3	S151	S147R	147	Missense	distal	-4	no	14.464	14.387	EPSD	ICGC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P15056	BRAF	P27361	MAPK3	S151	P152T	152	Missense	proximal	1	no	14.464	5.587	EPSD	ICGC	9.358	Loss
CMGC_MAPK_ERK1_MAPK3_ST	P15056	BRAF	P27361	MAPK3	S316	S317P	317	Missense	proximal	1	no	6.647	15.700	EPSD	ICGC	9.358	Gain
CMGC_MAPK_ERK1_MAPK3_ST	P15056	BRAF	P27361	MAPK3	S317	S316P	316	Missense	proximal	-1	no	15.604	15.610	EPSD	ICGC;COSMIC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P15056	BRAF	P27361	MAPK3	S317	P321H	321	Missense	distal	4	no	15.604	15.513	EPSD	ICGC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P15056	BRAF	P27361	MAPK3	S317	S317P	317	Missense	central	0	yes	15.604	0.000	EPSD	ICGC	9.358	Loss
CMGC_MAPK_ERK1_MAPK3_ST	P15056	BRAF	P27361	MAPK3	S319	S316P	316	Missense	distal	-3	no	11.603	11.611	EPSD	ICGC;COSMIC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P15056	BRAF	P27361	MAPK3	S319	I326V	326	Missense	distal	7	no	11.603	11.522	EPSD	ICGC;COSMIC;GDSC;CCLE	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P15056	BRAF	P27361	MAPK3	S319	P321H	321	Missense	proximal	2	no	11.603	11.589	EPSD	ICGC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P15056	BRAF	P27361	MAPK3	S319	S317P	317	Missense	proximal	-2	no	11.603	12.679	EPSD	ICGC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P15056	BRAF	P27361	MAPK3	S333	I326V	326	Missense	distal	-7	no	16.812	16.769	EPSD	ICGC;COSMIC;GDSC;CCLE	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P15056	BRAF	P27361	MAPK3	S333	P328F	328	Missense	distal	-5	no	16.812	16.682	EPSD	ICGC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P15056	BRAF	P27361	MAPK3	S333	P334L	334	Missense	proximal	1	no	16.812	7.774	EPSD	ICGC;COSMIC	9.358	Loss
CMGC_MAPK_ERK1_MAPK3_ST	P15056	BRAF	P27361	MAPK3	S335	P328F	328	Missense	distal	-7	no	16.219	16.400	EPSD	ICGC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P15056	BRAF	P27361	MAPK3	S335	P334L	334	Missense	proximal	-1	no	16.219	16.124	EPSD	ICGC;COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P15056	BRAF	P27361	MAPK3	T401	A404D	404	Missense	distal	3	no	15.379	15.413	PhosphoSitePlus;EPSD	ICGC;COSMIC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P15056	BRAF	P27361	MAPK3	T401	S394T	394	Missense	distal	-7	no	15.379	15.456	PhosphoSitePlus;EPSD	ICGC;COSMIC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P15056	BRAF	P27361	MAPK3	S419	Q423H	423	Missense	distal	4	no	14.652	14.703	EPSD	ICGC;COSMIC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P15056	BRAF	P27361	MAPK3	S428	S429Y	429	Missense	proximal	1	no	9.103	11.107	EPSD	ICGC	9.358	Gain
CMGC_MAPK_ERK1_MAPK3_ST	P15056	BRAF	P27361	MAPK3	S467	V471F	471	Missense	distal	4	no	10.411	10.220	EPSD	ICGC;COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P15056	BRAF	P27361	MAPK3	S467	Q461K	461	Missense	distal	-6	no	10.411	10.403	EPSD	ICGC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P15056	BRAF	P27361	MAPK3	S467	G466R	466	Missense	proximal	-1	no	10.411	10.435	EPSD	ICGC;COSMIC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P15056	BRAF	P27361	MAPK3	S467	S465Y	465	Missense	proximal	-2	no	10.411	10.178	EPSD	ICGC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P15056	BRAF	P27361	MAPK3	S467	R462K	462	Missense	distal	-5	no	10.411	10.410	EPSD	ICGC;COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P15056	BRAF	P27361	MAPK3	S675	R671Q	671	Missense	distal	-4	no	15.482	15.492	EPSD	ICGC;COSMIC;GDSC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P15056	BRAF	P27361	MAPK3	S675	D677N	677	Missense	proximal	2	no	15.482	15.476	EPSD	ICGC;COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P15056	BRAF	P27361	MAPK3	S675	R671L	671	Missense	distal	-4	no	15.482	15.419	EPSD	ICGC;COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P15056	BRAF	P27361	MAPK3	S750	S750Y	750	Missense	central	0	yes	17.108	0.000	EPSD	ICGC	9.358	Loss
CMGC_MAPK_ERK1_MAPK3_ST	P15056	BRAF	P27361	MAPK3	S750	Q756K	756	Missense	distal	6	no	17.108	17.212	EPSD	ICGC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P15056	BRAF	P27361	MAPK3	S750	P754T	754	Missense	distal	4	no	17.108	17.044	EPSD	ICGC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P15056	BRAF	P27361	MAPK3	T753	Y760H	760	Missense	distal	7	no	19.962	19.844	EPSD;PhosphoSitePlus	ICGC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P15056	BRAF	P27361	MAPK3	T753	S750Y	750	Missense	distal	-3	no	19.962	19.898	EPSD;PhosphoSitePlus	ICGC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P15056	BRAF	P27361	MAPK3	T753	Q756K	756	Missense	distal	3	no	19.962	19.960	EPSD;PhosphoSitePlus	ICGC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P15056	BRAF	P27361	MAPK3	T753	P754T	754	Missense	proximal	1	no	19.962	11.084	EPSD;PhosphoSitePlus	ICGC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P15056	BRAF	P27361	MAPK3	T753	G759E	759	Missense	distal	6	no	19.962	20.062	EPSD;PhosphoSitePlus	ICGC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P04626	ERBB2	P27361	MAPK3	T701	E695D	695	Missense	distal	-6	no	18.033	17.988	PhosphoSitePlus	ICGC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P04626	ERBB2	P27361	MAPK3	S760	A763T	763	Missense	distal	3	no	15.436	15.466	EPSD	ICGC;COSMIC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P10636	MAPT	P27361	MAPK3	T111	D116E	116	Missense	distal	5	no	15.249	15.267	EPSD	ICGC;COSMIC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P10636	MAPT	P27361	MAPK3	S228	P233H	233	Missense	distal	5	no	17.196	17.131	EPSD	ICGC;COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P10636	MAPT	P27361	MAPK3	S228	S232F	232	Missense	distal	4	no	17.196	16.781	EPSD	ICGC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P10636	MAPT	P27361	MAPK3	S228	D225N	225	Missense	distal	-3	no	17.196	17.174	EPSD	ICGC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P10636	MAPT	P27361	MAPK3	S228	V224I	224	Missense	distal	-4	no	17.196	17.188	EPSD	ICGC;COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P10636	MAPT	P27361	MAPK3	S232	P233H	233	Missense	proximal	1	no	16.576	8.820	EPSD	ICGC;COSMIC	9.358	Loss
CMGC_MAPK_ERK1_MAPK3_ST	P10636	MAPT	P27361	MAPK3	S232	S232F	232	Missense	central	0	yes	16.576	0.000	EPSD	ICGC	9.358	Loss
CMGC_MAPK_ERK1_MAPK3_ST	P10636	MAPT	P27361	MAPK3	S232	D225N	225	Missense	distal	-7	no	16.576	16.601	EPSD	ICGC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P10636	MAPT	P27361	MAPK3	S232	P239Q	239	Missense	distal	7	no	16.576	16.698	EPSD	ICGC;COSMIC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P10636	MAPT	P27361	MAPK3	S238	P233H	233	Missense	distal	-5	no	16.113	16.082	EPSD	ICGC;COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P10636	MAPT	P27361	MAPK3	S238	S232F	232	Missense	distal	-6	no	16.113	15.646	EPSD	ICGC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P10636	MAPT	P27361	MAPK3	S238	P239Q	239	Missense	proximal	1	no	16.113	8.169	EPSD	ICGC;COSMIC	9.358	Loss
CMGC_MAPK_ERK1_MAPK3_ST	P10636	MAPT	P27361	MAPK3	S428	S427F	427	Missense	proximal	-1	no	17.002	16.797	EPSD	ICGC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P10636	MAPT	P27361	MAPK3	S438	Y441H	441	Missense	distal	3	no	20.015	20.031	EPSD	ICGC;COSMIC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P10636	MAPT	P27361	MAPK3	S516	G521R	521	Missense	distal	5	no	17.816	17.737	EPSD	ICGC;COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P10636	MAPT	P27361	MAPK3	S519	G521R	521	Missense	proximal	2	no	18.268	18.272	EPSD	ICGC;COSMIC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P10636	MAPT	P27361	MAPK3	T522	G521R	521	Missense	proximal	-1	no	17.797	17.821	EPSD	ICGC;COSMIC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q13541	EIF4EBP1	P27361	MAPK3	T10	C7S	7	Missense	distal	-3	no	14.006	14.184	EPSD	ICGC;COSMIC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q13541	EIF4EBP1	P27361	MAPK3	T37	G40V	40	Missense	distal	3	no	14.992	14.970	EPSD	ICGC;COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q13541	EIF4EBP1	P27361	MAPK3	T37	S35I	35	Missense	proximal	-2	no	14.992	14.230	EPSD	ICGC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q13541	EIF4EBP1	P27361	MAPK3	T37	T41S	41	Missense	distal	4	no	14.992	15.105	EPSD	ICGC;COSMIC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q13541	EIF4EBP1	P27361	MAPK3	T46	G40V	40	Missense	distal	-6	no	15.828	15.561	EPSD	ICGC;COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q13541	EIF4EBP1	P27361	MAPK3	T46	T41S	41	Missense	distal	-5	no	15.828	15.843	EPSD	ICGC;COSMIC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q13541	EIF4EBP1	P27361	MAPK3	S65	P71A	71	Missense	distal	6	no	14.573	14.177	PhosphoSitePlus	ICGC;COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q13541	EIF4EBP1	P27361	MAPK3	S65	P71H	71	Missense	distal	6	no	14.573	14.480	PhosphoSitePlus	ICGC;COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q13541	EIF4EBP1	P27361	MAPK3	T70	P71A	71	Missense	proximal	1	no	16.526	7.287	EPSD	ICGC;COSMIC	9.358	Loss
CMGC_MAPK_ERK1_MAPK3_ST	Q13541	EIF4EBP1	P27361	MAPK3	T70	P71H	71	Missense	proximal	1	no	16.526	8.770	EPSD	ICGC;COSMIC	9.358	Loss
CMGC_MAPK_ERK1_MAPK3_ST	Q13541	EIF4EBP1	P27361	MAPK3	S94	S94I	94	Missense	central	0	yes	10.288	0.000	EPSD	ICGC	9.358	Loss
CMGC_MAPK_ERK1_MAPK3_ST	Q13541	EIF4EBP1	P27361	MAPK3	S94	H97Q	97	Missense	distal	3	no	10.288	10.280	EPSD	ICGC;COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q13541	EIF4EBP1	P27361	MAPK3	S94	S101C	101	Missense	distal	7	no	10.288	10.900	EPSD	ICGC;COSMIC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q13541	EIF4EBP1	P27361	MAPK3	S96	S94I	94	Missense	proximal	-2	no	11.635	10.873	EPSD	ICGC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q13541	EIF4EBP1	P27361	MAPK3	S96	H97Q	97	Missense	proximal	1	no	11.635	11.447	EPSD	ICGC;COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q13541	EIF4EBP1	P27361	MAPK3	S96	S101C	101	Missense	distal	5	no	11.635	11.112	EPSD	ICGC;COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q13541	EIF4EBP1	P27361	MAPK3	S101	S94I	94	Missense	distal	-7	no	17.868	18.059	EPSD	ICGC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q13541	EIF4EBP1	P27361	MAPK3	S101	R106Q	106	Missense	distal	5	no	17.868	17.866	EPSD	ICGC;COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q13541	EIF4EBP1	P27361	MAPK3	S101	G108C	108	Missense	distal	7	no	17.868	18.340	EPSD	ICGC;COSMIC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q13541	EIF4EBP1	P27361	MAPK3	S101	A107T	107	Missense	distal	6	no	17.868	18.238	EPSD	ICGC;COSMIC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q13541	EIF4EBP1	P27361	MAPK3	S101	D104Y	104	Missense	distal	3	no	17.868	17.848	EPSD	ICGC;COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q13541	EIF4EBP1	P27361	MAPK3	S101	H97Q	97	Missense	distal	-4	no	17.868	17.864	EPSD	ICGC;COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q13541	EIF4EBP1	P27361	MAPK3	S101	S101C	101	Missense	central	0	yes	17.868	0.000	EPSD	ICGC;COSMIC	9.358	Loss
CMGC_MAPK_ERK1_MAPK3_ST	Q13541	EIF4EBP1	P27361	MAPK3	S112	R106Q	106	Missense	distal	-6	no	10.620	10.629	EPSD	ICGC;COSMIC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q13541	EIF4EBP1	P27361	MAPK3	S112	G108C	108	Missense	distal	-4	no	10.620	10.420	EPSD	ICGC;COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q13541	EIF4EBP1	P27361	MAPK3	S112	E111D	111	Missense	proximal	-1	no	10.620	10.598	EPSD	ICGC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q13541	EIF4EBP1	P27361	MAPK3	S112	A107T	107	Missense	distal	-5	no	10.620	10.703	EPSD	ICGC;COSMIC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P49715	CEBPA	P27361	MAPK3	S190	S190P	190	Missense	central	0	yes	10.568	0.000	EPSD	ICGC;COSMIC	9.358	Loss
CMGC_MAPK_ERK1_MAPK3_ST	P49715	CEBPA	P27361	MAPK3	T226	P229H	229	Missense	distal	3	no	13.568	13.550	EPSD	ICGC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P49715	CEBPA	P27361	MAPK3	T230	P229H	229	Missense	proximal	-1	no	16.495	16.450	EPSD	ICGC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P49715	CEBPA	P27361	MAPK3	S234	A240V	240	Missense	distal	6	no	15.675	15.762	EPSD	ICGC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P49715	CEBPA	P27361	MAPK3	S234	P229H	229	Missense	distal	-5	no	15.675	15.644	EPSD	ICGC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P49715	CEBPA	P27361	MAPK3	S332	S332R	332	Missense	central	0	yes	10.348	0.000	EPSD	ICGC	9.358	Loss
CMGC_MAPK_ERK1_MAPK3_ST	P49715	CEBPA	P27361	MAPK3	S332	T337A	337	Missense	distal	5	no	10.348	10.229	EPSD	ICGC;COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q16828	DUSP6	P27361	MAPK3	S159	S154L	154	Missense	distal	-5	no	16.518	16.458	EPSD;PhosphoSitePlus	ICGC;COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q16828	DUSP6	P27361	MAPK3	S159	D152E	152	Missense	distal	-7	no	16.518	16.508	EPSD;PhosphoSitePlus	ICGC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q16828	DUSP6	P27361	MAPK3	S197	P198Q	198	Missense	proximal	1	no	17.628	9.684	EPSD;PhosphoSitePlus	ICGC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q16828	DUSP6	P27361	MAPK3	S205	P198Q	198	Missense	distal	-7	no	9.420	9.465	EPSD	ICGC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q16828	DUSP6	P27361	MAPK3	S351	E344K	344	Missense	distal	-7	no	16.986	17.038	EPSD	ICGC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q16828	DUSP6	P27361	MAPK3	S351	L347M	347	Missense	distal	-4	no	16.986	16.947	EPSD	ICGC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q16828	DUSP6	P27361	MAPK3	S351	D354N	354	Missense	distal	3	no	16.986	16.976	EPSD	ICGC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q16828	DUSP6	P27361	MAPK3	S351	T346M	346	Missense	distal	-5	no	16.986	16.884	EPSD	ICGC;COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P41235	HNF4A	P27361	MAPK3	S142	T139I	139	Missense	distal	-3	no	9.379	9.297	EPSD;PhosphoSitePlus	ICGC;COSMIC	9.358	Loss
CMGC_MAPK_ERK1_MAPK3_ST	P41235	HNF4A	P27361	MAPK3	S142	S148C	148	Missense	distal	6	no	9.379	8.511	EPSD;PhosphoSitePlus	ICGC;COSMIC	9.358	Loss
CMGC_MAPK_ERK1_MAPK3_ST	P41235	HNF4A	P27361	MAPK3	S142	D135G	135	Missense	distal	-7	no	9.379	9.374	EPSD;PhosphoSitePlus	ICGC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P41235	HNF4A	P27361	MAPK3	S142	S148I	148	Missense	distal	6	no	9.379	8.809	EPSD;PhosphoSitePlus	ICGC	9.358	Loss
CMGC_MAPK_ERK1_MAPK3_ST	P41235	HNF4A	P27361	MAPK3	S151	I152F	152	Missense	proximal	1	no	8.477	11.771	EPSD;PhosphoSitePlus	ICGC;COSMIC	9.358	Gain
CMGC_MAPK_ERK1_MAPK3_ST	P41235	HNF4A	P27361	MAPK3	S167	G174C	174	Missense	distal	7	no	14.115	14.587	EPSD;PhosphoSitePlus	ICGC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P41235	HNF4A	P27361	MAPK3	S167	V169I	169	Missense	proximal	2	no	14.115	14.105	EPSD;PhosphoSitePlus	ICGC;GDSC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P41235	HNF4A	P27361	MAPK3	S378	M373L	373	Missense	distal	-5	no	16.130	16.189	EPSD	ICGC;COSMIC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P41235	HNF4A	P27361	MAPK3	S378	G377R	377	Missense	proximal	-1	no	16.130	16.155	EPSD	ICGC;COSMIC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P41235	HNF4A	P27361	MAPK3	S378	S380R	380	Missense	proximal	2	no	16.130	16.118	EPSD	ICGC;COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P41235	HNF4A	P27361	MAPK3	T429	P423S	423	Missense	distal	-6	no	13.500	13.584	EPSD	ICGC;COSMIC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q9NYV6	RRN3	P27361	MAPK3	S17	S18F	18	Missense	proximal	1	no	7.655	10.495	EPSD	ICGC	9.358	Gain
CMGC_MAPK_ERK1_MAPK3_ST	Q9NYV6	RRN3	P27361	MAPK3	S172	V169F	169	Missense	distal	-3	no	10.486	10.417	EPSD	ICGC;COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q9NYV6	RRN3	P27361	MAPK3	T200	S199L	199	Missense	proximal	-1	no	16.458	16.369	EPSD	ICGC;COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q9NYV6	RRN3	P27361	MAPK3	T200	P201S	201	Missense	proximal	1	no	16.458	7.404	EPSD	ICGC;COSMIC	9.358	Loss
CMGC_MAPK_ERK1_MAPK3_ST	Q9NYV6	RRN3	P27361	MAPK3	S409	F410L	410	Missense	proximal	1	no	10.269	7.445	EPSD	ICGC	9.358	Loss
CMGC_MAPK_ERK1_MAPK3_ST	Q9NYV6	RRN3	P27361	MAPK3	S409	A412S	412	Missense	distal	3	no	10.269	10.313	EPSD	ICGC;COSMIC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q9NYV6	RRN3	P27361	MAPK3	S409	F416C	416	Missense	distal	7	no	10.269	10.390	EPSD	ICGC;COSMIC;CCLE	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P07101	TH	P27361	MAPK3	T3	P9Q	9	Missense	distal	6	no	12.306	12.125	EPSD	ICGC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P07101	TH	P27361	MAPK3	T3	Q10R	10	Missense	distal	7	no	12.306	12.276	EPSD	ICGC;COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P07101	TH	P27361	MAPK3	T8	K12R	12	Missense	distal	4	no	13.260	13.252	EPSD	ICGC;COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P07101	TH	P27361	MAPK3	T8	P9Q	9	Missense	proximal	1	no	13.260	5.316	EPSD	ICGC	9.358	Loss
CMGC_MAPK_ERK1_MAPK3_ST	P07101	TH	P27361	MAPK3	T8	Q10R	10	Missense	proximal	2	no	13.260	13.270	EPSD	ICGC;COSMIC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P07101	TH	P27361	MAPK3	S19	E20Q	20	Missense	proximal	1	no	8.289	9.593	EPSD	ICGC;COSMIC	9.358	Gain
CMGC_MAPK_ERK1_MAPK3_ST	P49790	NUP153	P27361	MAPK3	T102	P105T	105	Missense	distal	3	no	13.795	13.777	EPSD	ICGC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P49790	NUP153	P27361	MAPK3	S164	L165P	165	Missense	proximal	1	no	4.648	13.686	EPSD	ICGC;COSMIC	9.358	Gain
CMGC_MAPK_ERK1_MAPK3_ST	P49790	NUP153	P27361	MAPK3	S174	E168Q	168	Missense	distal	-6	no	10.339	10.205	EPSD	ICGC;COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P49790	NUP153	P27361	MAPK3	S215	L218H	218	Missense	distal	3	no	10.514	10.532	EPSD	ICGC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P49790	NUP153	P27361	MAPK3	S240	P241H	241	Missense	proximal	1	no	16.590	8.834	EPSD	ICGC	9.358	Loss
CMGC_MAPK_ERK1_MAPK3_ST	P49790	NUP153	P27361	MAPK3	T281	P282T	282	Missense	proximal	1	no	13.963	5.086	EPSD	ICGC	9.358	Loss
CMGC_MAPK_ERK1_MAPK3_ST	P49790	NUP153	P27361	MAPK3	T281	A285E	285	Missense	distal	4	no	13.963	14.194	EPSD	ICGC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P49790	NUP153	P27361	MAPK3	S334	N337K	337	Missense	distal	3	no	14.207	14.204	EPSD;PhosphoSitePlus	ICGC;COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P49790	NUP153	P27361	MAPK3	S334	P329T	329	Missense	distal	-5	no	14.207	14.196	EPSD;PhosphoSitePlus	ICGC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P49790	NUP153	P27361	MAPK3	S334	L340F	340	Missense	distal	6	no	14.207	13.850	EPSD;PhosphoSitePlus	ICGC;COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P49790	NUP153	P27361	MAPK3	S338	N337K	337	Missense	proximal	-1	no	16.571	16.565	EPSD;PhosphoSitePlus	ICGC;COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P49790	NUP153	P27361	MAPK3	S338	L340F	340	Missense	proximal	2	no	16.571	16.544	EPSD;PhosphoSitePlus	ICGC;COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P49790	NUP153	P27361	MAPK3	T369	P362L	362	Missense	distal	-7	no	15.353	15.461	EPSD;PhosphoSitePlus	ICGC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P49790	NUP153	P27361	MAPK3	T369	Q365K	365	Missense	distal	-4	no	15.353	15.336	EPSD;PhosphoSitePlus	ICGC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P49790	NUP153	P27361	MAPK3	T369	L367I	367	Missense	proximal	-2	no	15.353	14.899	EPSD;PhosphoSitePlus	ICGC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P49790	NUP153	P27361	MAPK3	T369	P372T	372	Missense	distal	3	no	15.353	15.335	EPSD;PhosphoSitePlus	ICGC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P49790	NUP153	P27361	MAPK3	T388	P385Q	385	Missense	distal	-3	no	14.277	14.223	EPSD;PhosphoSitePlus	ICGC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P49790	NUP153	P27361	MAPK3	T388	L387M	387	Missense	proximal	-1	no	14.277	14.210	EPSD;PhosphoSitePlus	ICGC;COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P49790	NUP153	P27361	MAPK3	T388	R394M	394	Missense	distal	6	no	14.277	13.869	EPSD;PhosphoSitePlus	ICGC;COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P49790	NUP153	P27361	MAPK3	T486	E493V	493	Missense	distal	7	no	10.174	10.388	EPSD	ICGC;COSMIC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P49790	NUP153	P27361	MAPK3	S491	S497F	497	Missense	distal	6	no	15.623	14.910	EPSD	ICGC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P49790	NUP153	P27361	MAPK3	S491	E493V	493	Missense	proximal	2	no	15.623	15.607	EPSD	ICGC;COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P49790	NUP153	P27361	MAPK3	S498	S497F	497	Missense	proximal	-1	no	15.717	15.513	EPSD	ICGC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P49790	NUP153	P27361	MAPK3	S498	E493V	493	Missense	distal	-5	no	15.717	15.676	EPSD	ICGC;COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P49790	NUP153	P27361	MAPK3	S500	S497F	497	Missense	distal	-3	no	16.603	16.462	EPSD	ICGC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P49790	NUP153	P27361	MAPK3	S500	E493V	493	Missense	distal	-7	no	16.603	16.720	EPSD	ICGC;COSMIC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P49790	NUP153	P27361	MAPK3	S516	P523T	523	Missense	distal	7	no	17.006	17.047	PhosphoSitePlus;EPSD	ICGC;COSMIC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P49790	NUP153	P27361	MAPK3	S516	K511N	511	Missense	distal	-5	no	17.006	17.012	PhosphoSitePlus;EPSD	ICGC;COSMIC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P49790	NUP153	P27361	MAPK3	S522	P523T	523	Missense	proximal	1	no	16.518	7.641	EPSD;PhosphoSitePlus	ICGC;COSMIC	9.358	Loss
CMGC_MAPK_ERK1_MAPK3_ST	P49790	NUP153	P27361	MAPK3	S529	P523T	523	Missense	distal	-6	no	15.387	15.304	EPSD;PhosphoSitePlus	ICGC;COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P49790	NUP153	P27361	MAPK3	S529	S534Y	534	Missense	distal	5	no	15.387	15.171	EPSD;PhosphoSitePlus	ICGC;COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P49790	NUP153	P27361	MAPK3	T588	N581D	581	Missense	distal	-7	no	14.960	14.936	EPSD	ICGC;COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P49790	NUP153	P27361	MAPK3	S614	S619L	619	Missense	distal	5	no	15.797	15.526	EPSD	ICGC;COSMIC;GDSC;CCLE	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P49790	NUP153	P27361	MAPK3	S619	S619L	619	Missense	central	0	yes	14.573	0.000	EPSD	ICGC;COSMIC;GDSC;CCLE	9.358	Loss
CMGC_MAPK_ERK1_MAPK3_ST	P49790	NUP153	P27361	MAPK3	S633	P640T	640	Missense	distal	7	no	15.589	15.630	EPSD	ICGC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P49790	NUP153	P27361	MAPK3	T699	T695S	695	Missense	distal	-4	no	15.269	15.327	EPSD	ICGC;COSMIC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P49790	NUP153	P27361	MAPK3	T747	K741T	741	Missense	distal	-6	no	13.833	13.823	EPSD	ICGC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P49790	NUP153	P27361	MAPK3	T747	T747K	747	Missense	central	0	yes	13.833	0.000	EPSD	ICGC	9.358	Loss
CMGC_MAPK_ERK1_MAPK3_ST	P49790	NUP153	P27361	MAPK3	T747	P748Q	748	Missense	proximal	1	no	13.833	5.889	EPSD	ICGC	9.358	Loss
CMGC_MAPK_ERK1_MAPK3_ST	P49790	NUP153	P27361	MAPK3	S902	F903L	903	Missense	proximal	1	no	13.463	10.639	EPSD	ICGC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P49790	NUP153	P27361	MAPK3	S902	F903V	903	Missense	proximal	1	no	13.463	10.254	EPSD	ICGC;COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P49790	NUP153	P27361	MAPK3	S902	S901L	901	Missense	proximal	-1	no	13.463	13.374	EPSD	ICGC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P49790	NUP153	P27361	MAPK3	T1032	N1030S	1030	Missense	proximal	-2	no	14.509	15.453	EPSD	ICGC;COSMIC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P49790	NUP153	P27361	MAPK3	S1152	S1154T	1154	Missense	proximal	2	no	10.188	10.177	EPSD	ICGC;COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P49790	NUP153	P27361	MAPK3	S1152	P1158Q	1158	Missense	distal	6	no	10.188	10.007	EPSD	ICGC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P04049	RAF1	P27361	MAPK3	S25	T31P	31	Missense	distal	6	no	10.015	10.040	EPSD	ICGC;COSMIC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P04049	RAF1	P27361	MAPK3	S25	S29R	29	Missense	distal	4	no	10.015	9.869	EPSD	ICGC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P04049	RAF1	P27361	MAPK3	S29	T31P	31	Missense	proximal	2	no	15.915	15.924	EPSD	ICGC;COSMIC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P04049	RAF1	P27361	MAPK3	S29	S29R	29	Missense	central	0	yes	15.915	0.000	EPSD	ICGC	9.358	Loss
CMGC_MAPK_ERK1_MAPK3_ST	Q16690	DUSP5	P27361	MAPK3	T321	S320F	320	Missense	proximal	-1	no	16.427	16.223	EPSD;PhosphoSitePlus	ICGC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q16690	DUSP5	P27361	MAPK3	S346	S346N	346	Missense	central	0	yes	16.493	0.000	EPSD;PhosphoSitePlus	ICGC;COSMIC	9.358	Loss
CMGC_MAPK_ERK1_MAPK3_ST	Q16690	DUSP5	P27361	MAPK3	S376	S374I	374	Missense	proximal	-2	no	18.334	17.572	PhosphoSitePlus;EPSD	ICGC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P15336	ATF2	P27361	MAPK3	S136	E130K	130	Missense	distal	-6	no	16.279	16.138	EPSD	ICGC;COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P15336	ATF2	P27361	MAPK3	T325	S321G	321	Missense	distal	-4	no	14.306	14.267	EPSD	ICGC;COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P15336	ATF2	P27361	MAPK3	S328	S321G	321	Missense	distal	-7	no	17.676	17.714	EPSD	ICGC;COSMIC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P15336	ATF2	P27361	MAPK3	T333	S340L	340	Missense	distal	7	no	15.687	15.957	EPSD	ICGC;COSMIC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P15336	ATF2	P27361	MAPK3	T333	Q337H	337	Missense	distal	4	no	15.687	15.737	EPSD	ICGC;COSMIC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P49023	PXN	P27361	MAPK3	S230	S226T	226	Missense	distal	-4	no	14.654	14.595	EPSD	ICGC;COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P49023	PXN	P27361	MAPK3	S320	S322L	322	Missense	proximal	2	no	10.939	10.916	EPSD	ICGC;COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P49023	PXN	P27361	MAPK3	S322	S322L	322	Missense	central	0	yes	17.609	0.000	EPSD	ICGC;COSMIC	9.358	Loss
CMGC_MAPK_ERK1_MAPK3_ST	P49023	PXN	P27361	MAPK3	S322	P328L	328	Missense	distal	6	no	17.609	17.383	EPSD	ICGC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P49023	PXN	P27361	MAPK3	S332	P328L	328	Missense	distal	-4	no	10.497	10.384	EPSD	ICGC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P42224	STAT1	P27361	MAPK3	S485	P491T	491	Missense	distal	6	no	10.553	10.528	EPSD	ICGC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P42224	STAT1	P27361	MAPK3	S485	R482M	482	Missense	distal	-3	no	10.553	10.463	EPSD	ICGC;COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P42224	STAT1	P27361	MAPK3	T489	P491T	491	Missense	proximal	2	no	11.420	11.410	EPSD	ICGC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P42224	STAT1	P27361	MAPK3	T489	R482M	482	Missense	distal	-7	no	11.420	11.542	EPSD	ICGC;COSMIC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P42224	STAT1	P27361	MAPK3	S606	F603L	603	Missense	distal	-3	no	10.573	10.639	EPSD	ICGC;COSMIC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P42224	STAT1	P27361	MAPK3	S606	R602W	602	Missense	distal	-4	no	10.573	10.366	EPSD	ICGC;GDSC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P42224	STAT1	P27361	MAPK3	S606	R602L	602	Missense	distal	-4	no	10.573	10.510	EPSD	ICGC;COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P42224	STAT1	P27361	MAPK3	S727	D721E	721	Missense	distal	-6	no	21.132	21.176	PhosphoSitePlus	ICGC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P42224	STAT1	P27361	MAPK3	S727	E733Q	733	Missense	distal	6	no	21.132	20.953	PhosphoSitePlus	ICGC;COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P42224	STAT1	P27361	MAPK3	S727	V734L	734	Missense	distal	7	no	21.132	21.084	PhosphoSitePlus	ICGC;COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P42224	STAT1	P27361	MAPK3	S735	R736Q	736	Missense	proximal	1	no	8.571	10.128	EPSD	ICGC;COSMIC	9.358	Gain
CMGC_MAPK_ERK1_MAPK3_ST	P14618	PKM	P27361	MAPK3	S37	D34E	34	Missense	distal	-3	no	16.418	16.421	PhosphoSitePlus	ICGC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P14618	PKM	P27361	MAPK3	S37	P38T	38	Missense	proximal	1	no	16.418	7.541	PhosphoSitePlus	ICGC	9.358	Loss
CMGC_MAPK_ERK1_MAPK3_ST	P14618	PKM	P27361	MAPK3	S55	R56Q	56	Missense	proximal	1	no	8.566	10.123	EPSD	ICGC;COSMIC	9.358	Gain
CMGC_MAPK_ERK1_MAPK3_ST	P14618	PKM	P27361	MAPK3	S182	L183F	183	Missense	proximal	1	no	7.620	10.444	EPSD	ICGC;COSMIC	9.358	Gain
CMGC_MAPK_ERK1_MAPK3_ST	P14618	PKM	P27361	MAPK3	S243	A248G	248	Missense	distal	5	no	10.490	10.681	EPSD	ICGC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P56270	MAZ	P27361	MAPK3	S468	E463D	463	Missense	distal	-5	no	12.051	12.050	EPSD	ICGC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P56270	MAZ	P27361	MAPK3	S468	Q470R	470	Missense	proximal	2	no	12.051	12.060	EPSD	ICGC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P56270	MAZ	P27361	MAPK3	S469	E463D	463	Missense	distal	-6	no	12.228	12.184	EPSD	ICGC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P56270	MAZ	P27361	MAPK3	S469	Q470R	470	Missense	proximal	1	no	12.228	10.671	EPSD	ICGC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P56270	MAZ	P27361	MAPK3	S474	Q470R	470	Missense	distal	-4	no	11.715	11.705	EPSD	ICGC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q9BUB5	MKNK1	P27361	MAPK3	T385	K381N	381	Missense	distal	-4	no	14.907	14.930	PhosphoSitePlus	ICGC;COSMIC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q9UJY1	HSPB8	P27361	MAPK3	S24	D23V	23	Missense	proximal	-1	no	19.917	19.880	PhosphoSitePlus;EPSD	ICGC;COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q9UJY1	HSPB8	P27361	MAPK3	S24	R18G	18	Missense	distal	-6	no	19.917	20.015	PhosphoSitePlus;EPSD	ICGC;COSMIC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q9UJY1	HSPB8	P27361	MAPK3	S24	R17H	17	Missense	distal	-7	no	19.917	19.906	PhosphoSitePlus;EPSD	ICGC;COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q9UJY1	HSPB8	P27361	MAPK3	S27	D23V	23	Missense	distal	-4	no	11.443	11.326	EPSD;PhosphoSitePlus	ICGC;COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q9UJY1	HSPB8	P27361	MAPK3	S104	L110V	110	Missense	distal	6	no	11.361	11.279	EPSD	ICGC;COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P53004	BLVRA	P27361	MAPK3	S211	E206Q	206	Missense	distal	-5	no	14.049	14.030	EPSD	ICGC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P53004	BLVRA	P27361	MAPK3	S211	S214L	214	Missense	distal	3	no	14.049	14.017	EPSD	ICGC;COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P53004	BLVRA	P27361	MAPK3	S230	S235T	235	Missense	distal	5	no	12.213	12.077	PhosphoSitePlus	ICGC;COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P38936	CDKN1A	P27361	MAPK3	T57	D52N	52	Missense	distal	-5	no	13.226	13.221	EPSD	ICGC;COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P38936	CDKN1A	P27361	MAPK3	T57	E56D	56	Missense	proximal	-1	no	13.226	13.204	EPSD	ICGC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P38936	CDKN1A	P27361	MAPK3	T57	F51V	51	Missense	distal	-6	no	13.226	13.364	EPSD	ICGC;COSMIC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P38936	CDKN1A	P27361	MAPK3	S130	P131T	131	Missense	proximal	1	no	16.417	7.540	PhosphoSitePlus;EPSD	ICGC;COSMIC	9.358	Loss
CMGC_MAPK_ERK1_MAPK3_ST	P38936	CDKN1A	P27361	MAPK3	S130	P131Q	131	Missense	proximal	1	no	16.417	8.473	PhosphoSitePlus;EPSD	ICGC;COSMIC	9.358	Loss
CMGC_MAPK_ERK1_MAPK3_ST	P38936	CDKN1A	P27361	MAPK3	S130	G129W	129	Missense	proximal	-1	no	16.417	16.203	PhosphoSitePlus;EPSD	ICGC;COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P38936	CDKN1A	P27361	MAPK3	S137	R143L	143	Missense	distal	6	no	10.411	10.297	EPSD	ICGC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P38936	CDKN1A	P27361	MAPK3	S137	R142Q	142	Missense	distal	5	no	10.411	10.410	EPSD	ICGC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P38936	CDKN1A	P27361	MAPK3	S137	P131T	131	Missense	distal	-6	no	10.411	10.328	EPSD	ICGC;COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P38936	CDKN1A	P27361	MAPK3	S137	P131Q	131	Missense	distal	-6	no	10.411	10.345	EPSD	ICGC;COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P38936	CDKN1A	P27361	MAPK3	T145	R143L	143	Missense	proximal	-2	no	9.904	9.920	EPSD	ICGC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P38936	CDKN1A	P27361	MAPK3	T145	R142Q	142	Missense	distal	-3	no	9.904	9.897	EPSD	ICGC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P38936	CDKN1A	P27361	MAPK3	T145	R140Q	140	Missense	distal	-5	no	9.904	9.897	EPSD	ICGC;COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q92934	BAD	P27361	MAPK3	S57	H61N	61	Missense	distal	4	no	9.816	9.810	EPSD	ICGC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q92934	BAD	P27361	MAPK3	S75	R72S	72	Missense	distal	-3	no	11.801	11.839	PhosphoSitePlus	ICGC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q92934	BAD	P27361	MAPK3	S75	T80K	80	Missense	distal	5	no	11.801	11.784	PhosphoSitePlus	ICGC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q92934	BAD	P27361	MAPK3	S75	S74G	74	Missense	proximal	-1	no	11.801	11.735	PhosphoSitePlus	ICGC;COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q92934	BAD	P27361	MAPK3	S91	R94W	94	Missense	distal	3	no	16.824	16.746	EPSD	ICGC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q92934	BAD	P27361	MAPK3	S144	R149L	149	Missense	distal	5	no	9.462	9.335	EPSD	ICGC;COSMIC	9.358	Loss
CMGC_MAPK_ERK1_MAPK3_ST	Q92934	BAD	P27361	MAPK3	S146	R149L	149	Missense	distal	3	no	12.087	12.077	EPSD	ICGC;COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q9H8Y8	GORASP2	P27361	MAPK3	S26	V22L	22	Missense	distal	-4	no	19.020	19.032	EPSD	ICGC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q9H8Y8	GORASP2	P27361	MAPK3	S26	P27L	27	Missense	proximal	1	no	19.020	9.982	EPSD	ICGC;COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q9H8Y8	GORASP2	P27361	MAPK3	S26	Q23K	23	Missense	distal	-3	no	19.020	19.014	EPSD	ICGC;COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q9H8Y8	GORASP2	P27361	MAPK3	S26	S26I	26	Missense	central	0	yes	19.020	0.000	EPSD	ICGC	9.358	Loss
CMGC_MAPK_ERK1_MAPK3_ST	Q9H8Y8	GORASP2	P27361	MAPK3	T222	M219V	219	Missense	distal	-3	no	14.203	14.258	PhosphoSitePlus;EPSD	ICGC;COSMIC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q9H8Y8	GORASP2	P27361	MAPK3	T222	G221D	221	Missense	proximal	-1	no	14.203	14.222	PhosphoSitePlus;EPSD	ICGC;COSMIC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q9H8Y8	GORASP2	P27361	MAPK3	T225	M219V	219	Missense	distal	-6	no	14.707	14.799	EPSD;PhosphoSitePlus	ICGC;COSMIC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q9H8Y8	GORASP2	P27361	MAPK3	T225	G221D	221	Missense	distal	-4	no	14.707	14.710	EPSD;PhosphoSitePlus	ICGC;COSMIC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q9H8Y8	GORASP2	P27361	MAPK3	S245	P242L	242	Missense	distal	-3	no	16.426	16.342	EPSD	ICGC;COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q9H8Y8	GORASP2	P27361	MAPK3	T415	T415M	415	Missense	central	0	yes	13.920	0.000	EPSD	ICGC;COSMIC	9.358	Loss
CMGC_MAPK_ERK1_MAPK3_ST	Q9H8Y8	GORASP2	P27361	MAPK3	S432	S432F	432	Missense	central	0	yes	11.605	0.000	EPSD	ICGC;COSMIC	9.358	Loss
CMGC_MAPK_ERK1_MAPK3_ST	Q9H8Y8	GORASP2	P27361	MAPK3	S432	E437K	437	Missense	distal	5	no	11.605	11.476	EPSD	ICGC;COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q9H8Y8	GORASP2	P27361	MAPK3	T433	V440D	440	Missense	distal	7	no	18.295	18.084	EPSD	ICGC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q9H8Y8	GORASP2	P27361	MAPK3	T433	S432F	432	Missense	proximal	-1	no	18.295	18.091	EPSD	ICGC;COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q9H8Y8	GORASP2	P27361	MAPK3	T433	E437K	437	Missense	distal	4	no	18.295	18.257	EPSD	ICGC;COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q9H8Y8	GORASP2	P27361	MAPK3	S436	V440D	440	Missense	distal	4	no	11.768	11.872	EPSD	ICGC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q9H8Y8	GORASP2	P27361	MAPK3	S436	S432F	432	Missense	distal	-4	no	11.768	11.579	EPSD	ICGC;COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q9H8Y8	GORASP2	P27361	MAPK3	S436	E437K	437	Missense	proximal	1	no	11.768	3.863	EPSD	ICGC;COSMIC	9.358	Loss
CMGC_MAPK_ERK1_MAPK3_ST	Q9H8Y8	GORASP2	P27361	MAPK3	S441	V440D	440	Missense	proximal	-1	no	10.611	10.648	EPSD	ICGC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q9H8Y8	GORASP2	P27361	MAPK3	S441	E437K	437	Missense	distal	-4	no	10.611	10.551	EPSD	ICGC;COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P19793	RXRA	P27361	MAPK3	S17	T23M	23	Missense	distal	6	no	9.954	9.460	EPSD	ICGC;COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P19793	RXRA	P27361	MAPK3	S17	D10Y	10	Missense	distal	-7	no	9.954	10.030	EPSD	ICGC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P19793	RXRA	P27361	MAPK3	S21	T23M	23	Missense	proximal	2	no	18.489	18.456	EPSD	ICGC;COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P19793	RXRA	P27361	MAPK3	S49	G42V	42	Missense	distal	-7	no	16.919	17.030	EPSD	ICGC;COSMIC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P19793	RXRA	P27361	MAPK3	T82	S88I	88	Missense	distal	6	no	16.644	16.075	EPSD	ICGC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P19793	RXRA	P27361	MAPK3	S225	E221D	221	Missense	distal	-4	no	9.861	9.850	EPSD	ICGC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P19793	RXRA	P27361	MAPK3	S225	S224I	224	Missense	proximal	-1	no	9.861	9.730	EPSD	ICGC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P19793	RXRA	P27361	MAPK3	S260	P258H	258	Missense	proximal	-2	no	19.444	18.216	PhosphoSitePlus	ICGC;COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P78536	ADAM17	P27361	MAPK3	S791	A789P	789	Missense	proximal	-2	no	8.981	11.332	EPSD	ICGC;COSMIC	9.358	Gain
CMGC_MAPK_ERK1_MAPK3_ST	P78536	ADAM17	P27361	MAPK3	T801	P799L	799	Missense	proximal	-2	no	9.682	8.298	EPSD	ICGC;COSMIC;GDSC;CCLE	9.358	Loss
CMGC_MAPK_ERK1_MAPK3_ST	P78536	ADAM17	P27361	MAPK3	T801	P799T	799	Missense	proximal	-2	no	9.682	8.697	EPSD	ICGC	9.358	Loss
CMGC_MAPK_ERK1_MAPK3_ST	Q8WX93	PALLD	P27361	MAPK3	S9	S13N	13	Missense	distal	4	no	9.510	9.364	EPSD	ICGC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q8WX93	PALLD	P27361	MAPK3	S9	S9N	9	Missense	central	0	yes	9.510	0.000	EPSD	ICGC	9.358	Loss
CMGC_MAPK_ERK1_MAPK3_ST	Q8WX93	PALLD	P27361	MAPK3	S15	S13N	13	Missense	proximal	-2	no	10.249	9.305	EPSD	ICGC	9.358	Loss
CMGC_MAPK_ERK1_MAPK3_ST	Q8WX93	PALLD	P27361	MAPK3	S15	M17I	17	Missense	proximal	2	no	10.249	10.257	EPSD	ICGC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q8WX93	PALLD	P27361	MAPK3	S15	S9N	9	Missense	distal	-6	no	10.249	10.126	EPSD	ICGC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q8WX93	PALLD	P27361	MAPK3	S71	H78N	78	Missense	distal	7	no	15.044	15.073	EPSD	ICGC;COSMIC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q8WX93	PALLD	P27361	MAPK3	S125	A123S	123	Missense	proximal	-2	no	14.755	16.030	EPSD	ICGC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q8WX93	PALLD	P27361	MAPK3	T147	K153N	153	Missense	distal	6	no	13.536	13.515	EPSD	ICGC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q8WX93	PALLD	P27361	MAPK3	S166	G162E	162	Missense	distal	-4	no	9.452	9.466	EPSD	ICGC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q8WX93	PALLD	P27361	MAPK3	T635	K631Q	631	Missense	distal	-4	no	14.894	14.911	EPSD	ICGC;COSMIC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q8WX93	PALLD	P27361	MAPK3	S641	P648H	648	Missense	distal	7	no	16.563	16.623	EPSD	ICGC;COSMIC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q8WX93	PALLD	P27361	MAPK3	S728	R733H	733	Missense	distal	5	no	9.737	9.773	EPSD	ICGC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q8WX93	PALLD	P27361	MAPK3	S979	E983D	983	Missense	distal	4	no	15.843	15.824	EPSD	ICGC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q9UBN7	HDAC6	P27361	MAPK3	S22	V29A	29	Missense	distal	7	no	19.697	19.725	EPSD	ICGC;COSMIC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q9UBN7	HDAC6	P27361	MAPK3	S28	V29A	29	Missense	proximal	1	no	9.646	9.829	EPSD	ICGC;COSMIC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q9UBN7	HDAC6	P27361	MAPK3	S886	T883S	883	Missense	distal	-3	no	9.709	9.739	EPSD	ICGC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q9UBN7	HDAC6	P27361	MAPK3	T1041	P1046S	1046	Missense	distal	5	no	14.772	14.815	EPSD	ICGC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q9UBN7	HDAC6	P27361	MAPK3	T1041	P1046L	1046	Missense	distal	5	no	14.772	14.545	EPSD	ICGC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q9UBN7	HDAC6	P27361	MAPK3	T1048	P1046S	1046	Missense	proximal	-2	no	9.982	8.906	EPSD	ICGC	9.358	Loss
CMGC_MAPK_ERK1_MAPK3_ST	Q9UBN7	HDAC6	P27361	MAPK3	T1048	P1046L	1046	Missense	proximal	-2	no	9.982	8.598	EPSD	ICGC	9.358	Loss
CMGC_MAPK_ERK1_MAPK3_ST	Q04637	EIF4G1	P27361	MAPK3	S15	P19L	19	Missense	distal	4	no	15.941	15.786	EPSD	ICGC;COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q04637	EIF4G1	P27361	MAPK3	S15	P14S	14	Missense	proximal	-1	no	15.941	15.935	EPSD	ICGC;COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q04637	EIF4G1	P27361	MAPK3	T43	A38S	38	Missense	distal	-5	no	12.683	12.781	EPSD	ICGC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q04637	EIF4G1	P27361	MAPK3	T43	S45F	45	Missense	proximal	2	no	12.683	12.632	EPSD	ICGC;COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q04637	EIF4G1	P27361	MAPK3	T205	P208S	208	Missense	distal	3	no	13.845	13.840	EPSD	ICGC;COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q04637	EIF4G1	P27361	MAPK3	T205	P208H	208	Missense	distal	3	no	13.845	13.826	EPSD	ICGC;GDSC;CCLE	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q04637	EIF4G1	P27361	MAPK3	T207	P208S	208	Missense	proximal	1	no	17.338	8.285	EPSD	ICGC;COSMIC	9.358	Loss
CMGC_MAPK_ERK1_MAPK3_ST	Q04637	EIF4G1	P27361	MAPK3	T207	P208H	208	Missense	proximal	1	no	17.338	9.583	EPSD	ICGC;GDSC;CCLE	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q04637	EIF4G1	P27361	MAPK3	T223	P224S	224	Missense	proximal	1	no	11.997	2.944	EPSD	ICGC;COSMIC	9.358	Loss
CMGC_MAPK_ERK1_MAPK3_ST	Q04637	EIF4G1	P27361	MAPK3	S314	P310L	310	Missense	distal	-4	no	16.880	16.767	EPSD	ICGC;COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q04637	EIF4G1	P27361	MAPK3	S314	P310H	310	Missense	distal	-4	no	16.880	16.845	EPSD	ICGC;COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q04637	EIF4G1	P27361	MAPK3	S416	E420K	420	Missense	distal	4	no	15.309	15.270	EPSD	ICGC;COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q04637	EIF4G1	P27361	MAPK3	S450	T449I	449	Missense	proximal	-1	no	15.530	15.429	EPSD	ICGC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q04637	EIF4G1	P27361	MAPK3	S1092	A1086S	1086	Missense	distal	-6	no	9.074	9.391	EPSD	ICGC;COSMIC	9.358	Gain
CMGC_MAPK_ERK1_MAPK3_ST	Q04637	EIF4G1	P27361	MAPK3	T1179	R1184Q	1184	Missense	distal	5	no	14.976	14.975	EPSD	ICGC;COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q04637	EIF4G1	P27361	MAPK3	S1185	R1184Q	1184	Missense	proximal	-1	no	9.656	9.617	EPSD	ICGC;COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P50616	TOB1	P27361	MAPK3	S147	P153S	153	Missense	distal	6	no	10.821	10.950	EPSD	ICGC;COSMIC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P50616	TOB1	P27361	MAPK3	S152	P153S	153	Missense	proximal	1	no	16.831	7.778	EPSD;PhosphoSitePlus	ICGC;COSMIC	9.358	Loss
CMGC_MAPK_ERK1_MAPK3_ST	P50616	TOB1	P27361	MAPK3	S152	H159N	159	Missense	distal	7	no	16.831	16.860	EPSD;PhosphoSitePlus	ICGC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P50616	TOB1	P27361	MAPK3	S154	P153S	153	Missense	proximal	-1	no	17.394	17.388	PhosphoSitePlus;EPSD	ICGC;COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P50616	TOB1	P27361	MAPK3	S154	H159N	159	Missense	distal	5	no	17.394	17.380	PhosphoSitePlus;EPSD	ICGC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P50616	TOB1	P27361	MAPK3	S164	H159N	159	Missense	distal	-5	no	16.627	16.623	EPSD;PhosphoSitePlus	ICGC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P50616	TOB1	P27361	MAPK3	T166	H159N	159	Missense	distal	-7	no	9.578	9.574	EPSD	ICGC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P50616	TOB1	P27361	MAPK3	S205	V201G	201	Missense	distal	-4	no	16.223	16.336	EPSD	ICGC;COSMIC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P50616	TOB1	P27361	MAPK3	S205	R203S	203	Missense	proximal	-2	no	16.223	16.547	EPSD	ICGC;COSMIC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P50616	TOB1	P27361	MAPK3	S268	K263N	263	Missense	distal	-5	no	16.658	16.664	EPSD	ICGC;COSMIC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P49815	TSC2	P27361	MAPK3	S540	R537L	537	Missense	distal	-3	no	16.225	16.187	EPSD	ICGC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P49815	TSC2	P27361	MAPK3	S664	G671A	671	Missense	distal	7	no	18.206	18.413	PhosphoSitePlus	ICGC;COSMIC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P49815	TSC2	P27361	MAPK3	S923	E929K	929	Missense	distal	6	no	11.019	10.942	EPSD	ICGC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P49815	TSC2	P27361	MAPK3	T927	E929K	929	Missense	proximal	2	no	15.895	15.888	EPSD	ICGC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P49815	TSC2	P27361	MAPK3	T927	R934M	934	Missense	distal	7	no	15.895	16.176	EPSD	ICGC;COSMIC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P49815	TSC2	P27361	MAPK3	S960	L957F	957	Missense	distal	-3	no	14.575	14.509	EPSD	ICGC;COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P49815	TSC2	P27361	MAPK3	S1002	S1002F	1002	Missense	central	0	yes	9.362	0.000	EPSD	ICGC;COSMIC	9.358	Loss
CMGC_MAPK_ERK1_MAPK3_ST	P49815	TSC2	P27361	MAPK3	S1002	S1002Y	1002	Missense	central	0	yes	9.362	0.000	EPSD	ICGC;COSMIC	9.358	Loss
CMGC_MAPK_ERK1_MAPK3_ST	P49815	TSC2	P27361	MAPK3	S1045	G1048S	1048	Missense	distal	3	no	14.972	14.987	EPSD	ICGC;COSMIC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P49815	TSC2	P27361	MAPK3	S1387	S1388L	1388	Missense	proximal	1	no	9.585	9.600	EPSD	ICGC;COSMIC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P49815	TSC2	P27361	MAPK3	S1388	S1388L	1388	Missense	central	0	yes	16.488	0.000	EPSD	ICGC;COSMIC	9.358	Loss
CMGC_MAPK_ERK1_MAPK3_ST	P10415	BCL2	P27361	MAPK3	S24	K22R	22	Missense	proximal	-2	no	8.911	9.852	EPSD	ICGC;COSMIC	9.358	Gain
CMGC_MAPK_ERK1_MAPK3_ST	P10415	BCL2	P27361	MAPK3	T56	A60V	60	Missense	distal	4	no	15.980	16.088	EPSD;PhosphoSitePlus	ICGC;COSMIC;GDSC;CCLE	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P10415	BCL2	P27361	MAPK3	T56	H58Q	58	Missense	proximal	2	no	15.980	15.973	EPSD;PhosphoSitePlus	ICGC;COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P10415	BCL2	P27361	MAPK3	T56	H58P	58	Missense	proximal	2	no	15.980	15.993	EPSD;PhosphoSitePlus	ICGC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P10415	BCL2	P27361	MAPK3	T56	P59A	59	Missense	distal	3	no	15.980	15.931	EPSD;PhosphoSitePlus	ICGC;COSMIC;GDSC;CCLE	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P10415	BCL2	P27361	MAPK3	T56	S62F	62	Missense	distal	6	no	15.980	15.266	EPSD;PhosphoSitePlus	ICGC;COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P10415	BCL2	P27361	MAPK3	T56	P59S	59	Missense	distal	3	no	15.980	15.975	EPSD;PhosphoSitePlus	ICGC;COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P10415	BCL2	P27361	MAPK3	T56	P53S	53	Missense	distal	-3	no	15.980	15.971	EPSD;PhosphoSitePlus	ICGC;COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P10415	BCL2	P27361	MAPK3	T56	P59L	59	Missense	distal	3	no	15.980	15.943	EPSD;PhosphoSitePlus	ICGC;COSMIC;GDSC;CCLE	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P10415	BCL2	P27361	MAPK3	T56	Q52R	52	Missense	distal	-4	no	15.980	15.970	EPSD;PhosphoSitePlus	ICGC;COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P10415	BCL2	P27361	MAPK3	T56	F49L	49	Missense	distal	-7	no	15.980	15.905	EPSD;PhosphoSitePlus	ICGC;COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P10415	BCL2	P27361	MAPK3	T56	A60T	60	Missense	distal	4	no	15.980	16.198	EPSD;PhosphoSitePlus	ICGC;COSMIC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P10415	BCL2	P27361	MAPK3	T56	T56M	56	Missense	central	0	yes	15.980	0.000	EPSD;PhosphoSitePlus	ICGC	9.358	Loss
CMGC_MAPK_ERK1_MAPK3_ST	P10415	BCL2	P27361	MAPK3	T74	A81V	81	Missense	distal	7	no	17.429	17.401	PhosphoSitePlus;EPSD	ICGC;COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P10415	BCL2	P27361	MAPK3	S87	P88Q	88	Missense	proximal	1	no	13.964	6.020	EPSD;PhosphoSitePlus	ICGC;COSMIC	9.358	Loss
CMGC_MAPK_ERK1_MAPK3_ST	P10415	BCL2	P27361	MAPK3	S87	L86V	86	Missense	proximal	-1	no	13.964	13.968	EPSD;PhosphoSitePlus	ICGC;COSMIC;GDSC;CCLE	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P10415	BCL2	P27361	MAPK3	S87	S87R	87	Missense	central	0	yes	13.964	0.000	EPSD;PhosphoSitePlus	ICGC;COSMIC	9.358	Loss
CMGC_MAPK_ERK1_MAPK3_ST	P10415	BCL2	P27361	MAPK3	S87	A81V	81	Missense	distal	-6	no	13.964	13.951	EPSD;PhosphoSitePlus	ICGC;COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q9NQ66	PLCB1	P27361	MAPK3	T39	I41V	41	Missense	proximal	2	no	15.226	15.235	EPSD	ICGC;COSMIC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q9NQ66	PLCB1	P27361	MAPK3	T39	T45N	45	Missense	distal	6	no	15.226	15.152	EPSD	ICGC;COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q9NQ66	PLCB1	P27361	MAPK3	T39	D46H	46	Missense	distal	7	no	15.226	15.256	EPSD	ICGC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q9NQ66	PLCB1	P27361	MAPK3	T39	D32E	32	Missense	distal	-7	no	15.226	15.215	EPSD	ICGC;COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q9NQ66	PLCB1	P27361	MAPK3	S387	M382L	382	Missense	distal	-5	no	9.702	9.761	EPSD	ICGC;COSMIC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q9NQ66	PLCB1	P27361	MAPK3	S417	H414Y	414	Missense	distal	-3	no	16.108	16.076	EPSD	ICGC;COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q9NQ66	PLCB1	P27361	MAPK3	S454	M456V	456	Missense	proximal	2	no	15.399	15.417	EPSD	ICGC;COSMIC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q9NQ66	PLCB1	P27361	MAPK3	S454	P451S	451	Missense	distal	-3	no	15.399	15.390	EPSD	ICGC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q9NQ66	PLCB1	P27361	MAPK3	S454	S448Y	448	Missense	distal	-6	no	15.399	15.145	EPSD	ICGC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q9NQ66	PLCB1	P27361	MAPK3	S501	P502Q	502	Missense	proximal	1	no	17.376	9.432	EPSD	ICGC;COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q9NQ66	PLCB1	P27361	MAPK3	S582	P583Q	583	Missense	proximal	1	no	17.743	9.799	EPSD	ICGC;COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q9NQ66	PLCB1	P27361	MAPK3	T871	K873R	873	Missense	proximal	2	no	15.473	15.476	EPSD	ICGC;COSMIC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q9NQ66	PLCB1	P27361	MAPK3	T871	A878V	878	Missense	distal	7	no	15.473	15.445	EPSD	ICGC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q9NQ66	PLCB1	P27361	MAPK3	S876	K873R	873	Missense	distal	-3	no	9.885	9.899	EPSD	ICGC;COSMIC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q9NQ66	PLCB1	P27361	MAPK3	S876	A878V	878	Missense	proximal	2	no	9.885	9.899	EPSD	ICGC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q9NQ66	PLCB1	P27361	MAPK3	S982	D984Y	984	Missense	proximal	2	no	17.827	17.817	PhosphoSitePlus	ICGC;COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q9NQ66	PLCB1	P27361	MAPK3	S982	K976R	976	Missense	distal	-6	no	17.827	17.825	PhosphoSitePlus	ICGC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q9NQ66	PLCB1	P27361	MAPK3	T1197	E1201K	1201	Missense	distal	4	no	20.818	20.780	EPSD	ICGC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q9NQ66	PLCB1	P27361	MAPK3	T1197	K1196N	1196	Missense	proximal	-1	no	20.818	20.824	EPSD	ICGC;COSMIC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q9NQ66	PLCB1	P27361	MAPK3	T1197	G1191E	1191	Missense	distal	-6	no	20.818	20.864	EPSD	ICGC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q9NQ66	PLCB1	P27361	MAPK3	S1199	E1201K	1201	Missense	proximal	2	no	10.765	10.757	EPSD	ICGC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q9NQ66	PLCB1	P27361	MAPK3	S1199	K1196N	1196	Missense	distal	-3	no	10.765	10.771	EPSD	ICGC;COSMIC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q9NQ66	PLCB1	P27361	MAPK3	S1199	G1205R	1205	Missense	distal	6	no	10.765	10.755	EPSD	ICGC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q9NQ66	PLCB1	P27361	MAPK3	S1200	E1201K	1201	Missense	proximal	1	no	12.511	4.605	EPSD	ICGC	9.358	Loss
CMGC_MAPK_ERK1_MAPK3_ST	Q9NQ66	PLCB1	P27361	MAPK3	S1200	K1196N	1196	Missense	distal	-4	no	12.511	12.533	EPSD	ICGC;COSMIC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q9NQ66	PLCB1	P27361	MAPK3	S1200	G1205R	1205	Missense	distal	5	no	12.511	12.432	EPSD	ICGC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q13950	RUNX2	P27361	MAPK3	S24	F18V	18	Missense	distal	-6	no	10.701	10.838	EPSD;PhosphoSitePlus	ICGC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q13950	RUNX2	P27361	MAPK3	S275	P276S	276	Missense	proximal	1	no	15.279	6.225	EPSD;PhosphoSitePlus	ICGC	9.358	Loss
CMGC_MAPK_ERK1_MAPK3_ST	P17655	CAPN2	P27361	MAPK3	S50	P49Q	49	Missense	proximal	-1	no	11.625	11.538	PhosphoSitePlus	ICGC;COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P17655	CAPN2	P27361	MAPK3	T344	R337H	337	Missense	distal	-7	no	14.586	14.575	EPSD	ICGC;COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P17655	CAPN2	P27361	MAPK3	T344	R337L	337	Missense	distal	-7	no	14.586	14.648	EPSD	ICGC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P17655	CAPN2	P27361	MAPK3	T344	S350I	350	Missense	distal	6	no	14.586	14.016	EPSD	ICGC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P17655	CAPN2	P27361	MAPK3	T344	D351N	351	Missense	distal	7	no	14.586	14.645	EPSD	ICGC;COSMIC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P17655	CAPN2	P27361	MAPK3	T352	S350I	350	Missense	proximal	-2	no	11.157	10.395	EPSD	ICGC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P17655	CAPN2	P27361	MAPK3	T352	D351N	351	Missense	proximal	-1	no	11.157	11.155	EPSD	ICGC;COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P17655	CAPN2	P27361	MAPK3	T380	C374Y	374	Missense	distal	-6	no	10.301	10.606	EPSD	ICGC;COSMIC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P17655	CAPN2	P27361	MAPK3	T380	P385S	385	Missense	distal	5	no	10.301	10.344	EPSD	ICGC;COSMIC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P17655	CAPN2	P27361	MAPK3	T406	G404S	404	Missense	proximal	-2	no	9.557	10.597	EPSD	ICGC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P17655	CAPN2	P27361	MAPK3	T464	A458T	458	Missense	distal	-6	no	9.340	9.488	EPSD	ICGC;COSMIC;GDSC;CCLE	9.358	Gain
CMGC_MAPK_ERK1_MAPK3_ST	P28324	ELK4	P27361	MAPK3	S180	K178T	178	Missense	proximal	-2	no	17.767	19.122	EPSD	ICGC;COSMIC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P28324	ELK4	P27361	MAPK3	S180	K179T	179	Missense	proximal	-1	no	17.767	17.792	EPSD	ICGC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P28324	ELK4	P27361	MAPK3	T185	K178T	178	Missense	distal	-7	no	14.448	14.440	EPSD	ICGC;COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P28324	ELK4	P27361	MAPK3	T185	K179T	179	Missense	distal	-6	no	14.448	14.438	EPSD	ICGC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P28324	ELK4	P27361	MAPK3	T194	P199S	199	Missense	distal	5	no	16.000	16.043	EPSD	ICGC;COSMIC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P28324	ELK4	P27361	MAPK3	S215	S209L	209	Missense	distal	-6	no	16.641	16.309	EPSD	ICGC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P28324	ELK4	P27361	MAPK3	S230	P231Q	231	Missense	proximal	1	no	17.506	9.563	EPSD	ICGC;COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P28324	ELK4	P27361	MAPK3	S230	T227A	227	Missense	distal	-3	no	17.506	17.445	EPSD	ICGC;COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P28324	ELK4	P27361	MAPK3	S381	P388T	388	Missense	distal	7	no	16.534	16.575	EPSD;PhosphoSitePlus	ICGC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P28324	ELK4	P27361	MAPK3	S381	P388Q	388	Missense	distal	7	no	16.534	16.656	EPSD;PhosphoSitePlus	ICGC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P28324	ELK4	P27361	MAPK3	S381	W377L	377	Missense	distal	-4	no	16.534	16.678	EPSD;PhosphoSitePlus	ICGC;COSMIC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P28324	ELK4	P27361	MAPK3	S381	A384S	384	Missense	distal	3	no	16.534	16.578	EPSD;PhosphoSitePlus	ICGC;COSMIC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P28324	ELK4	P27361	MAPK3	S387	P388T	388	Missense	proximal	1	no	17.434	8.557	PhosphoSitePlus;EPSD	ICGC	9.358	Loss
CMGC_MAPK_ERK1_MAPK3_ST	P28324	ELK4	P27361	MAPK3	S387	P388Q	388	Missense	proximal	1	no	17.434	9.490	PhosphoSitePlus;EPSD	ICGC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P28324	ELK4	P27361	MAPK3	S387	G393C	393	Missense	distal	6	no	17.434	16.799	PhosphoSitePlus;EPSD	ICGC;COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P28324	ELK4	P27361	MAPK3	S387	A384S	384	Missense	distal	-3	no	17.434	17.525	PhosphoSitePlus;EPSD	ICGC;COSMIC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P28324	ELK4	P27361	MAPK3	S419	G417R	417	Missense	proximal	-2	no	8.886	9.603	EPSD	ICGC	9.358	Gain
CMGC_MAPK_ERK1_MAPK3_ST	P28324	ELK4	P27361	MAPK3	T420	P418S	418	Missense	proximal	-2	no	18.224	17.148	EPSD	ICGC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P28324	ELK4	P27361	MAPK3	T420	G417R	417	Missense	distal	-3	no	18.224	18.219	EPSD	ICGC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P28324	ELK4	P27361	MAPK3	T420	G422C	422	Missense	proximal	2	no	18.224	18.179	EPSD	ICGC;COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P28324	ELK4	P27361	MAPK3	T420	P421T	421	Missense	proximal	1	no	18.224	9.347	EPSD	ICGC;COSMIC	9.358	Loss
CMGC_MAPK_ERK1_MAPK3_ST	P28324	ELK4	P27361	MAPK3	T420	P423L	423	Missense	distal	3	no	18.224	18.187	EPSD	ICGC;COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P28324	ELK4	P27361	MAPK3	T420	P423Q	423	Missense	distal	3	no	18.224	18.197	EPSD	ICGC;COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P28324	ELK4	P27361	MAPK3	T420	T420A	420	Missense	central	0	yes	18.224	0.000	EPSD	ICGC	9.358	Loss
CMGC_MAPK_ERK1_MAPK3_ST	P28324	ELK4	P27361	MAPK3	S425	P418S	418	Missense	distal	-7	no	22.250	22.212	EPSD	ICGC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P28324	ELK4	P27361	MAPK3	S425	G422C	422	Missense	distal	-3	no	22.250	22.105	EPSD	ICGC;COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P28324	ELK4	P27361	MAPK3	S425	P421T	421	Missense	distal	-4	no	22.250	22.219	EPSD	ICGC;COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P28324	ELK4	P27361	MAPK3	S425	P423L	423	Missense	proximal	-2	no	22.250	20.866	EPSD	ICGC;COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P28324	ELK4	P27361	MAPK3	S425	P423Q	423	Missense	proximal	-2	no	22.250	20.486	EPSD	ICGC;COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P28324	ELK4	P27361	MAPK3	S425	T420A	420	Missense	distal	-5	no	22.250	22.167	EPSD	ICGC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	O75030	MITF	P27361	MAPK3	S414	R420W	420	Missense	distal	6	no	16.855	16.032	EPSD	ICGC;COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	O75030	MITF	P27361	MAPK3	S414	D416N	416	Missense	proximal	2	no	16.855	16.849	EPSD	ICGC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	O75030	MITF	P27361	MAPK3	S491	G494D	494	Missense	distal	3	no	15.940	15.945	EPSD	ICGC;COSMIC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	O75030	MITF	P27361	MAPK3	S491	D488N	488	Missense	distal	-3	no	15.940	15.918	EPSD	ICGC;COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	O75030	MITF	P27361	MAPK3	S491	T496N	496	Missense	distal	5	no	15.940	15.953	EPSD	ICGC;COSMIC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	O75030	MITF	P27361	MAPK3	S491	D488G	488	Missense	distal	-3	no	15.940	15.930	EPSD	ICGC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	O75030	MITF	P27361	MAPK3	S491	L490F	490	Missense	proximal	-1	no	15.940	15.825	EPSD	ICGC;COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	O75030	MITF	P27361	MAPK3	S491	D497G	497	Missense	distal	6	no	15.940	15.884	EPSD	ICGC;COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	O75030	MITF	P27361	MAPK3	S504	G506R	506	Missense	proximal	2	no	19.521	19.526	EPSD	ICGC;COSMIC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	O75030	MITF	P27361	MAPK3	S504	S504C	504	Missense	central	0	yes	19.521	0.000	EPSD	ICGC;COSMIC	9.358	Loss
CMGC_MAPK_ERK1_MAPK3_ST	O75030	MITF	P27361	MAPK3	S504	S504P	504	Missense	central	0	yes	19.521	0.000	EPSD	ICGC	9.358	Loss
CMGC_MAPK_ERK1_MAPK3_ST	O75030	MITF	P27361	MAPK3	S504	D497G	497	Missense	distal	-7	no	19.521	19.517	EPSD	ICGC;COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	O75030	MITF	P27361	MAPK3	S504	L500F	500	Missense	distal	-4	no	19.521	19.473	EPSD	ICGC;COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	O75030	MITF	P27361	MAPK3	T510	G506R	506	Missense	distal	-4	no	10.527	10.489	EPSD	ICGC;COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	O75030	MITF	P27361	MAPK3	T510	S504C	504	Missense	distal	-6	no	10.527	9.968	EPSD	ICGC;COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	O75030	MITF	P27361	MAPK3	T510	S504P	504	Missense	distal	-6	no	10.527	10.443	EPSD	ICGC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	O75030	MITF	P27361	MAPK3	S511	G506R	506	Missense	distal	-5	no	9.833	9.830	EPSD	ICGC;COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	O75030	MITF	P27361	MAPK3	S511	S504C	504	Missense	distal	-7	no	9.833	10.102	EPSD	ICGC;COSMIC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	O75030	MITF	P27361	MAPK3	S511	S504P	504	Missense	distal	-7	no	9.833	9.870	EPSD	ICGC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	O75030	MITF	P27361	MAPK3	S511	R513Q	513	Missense	proximal	2	no	9.833	9.823	EPSD	ICGC;COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	O75030	MITF	P27361	MAPK3	S512	G506R	506	Missense	distal	-6	no	10.216	10.118	EPSD	ICGC;COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	O75030	MITF	P27361	MAPK3	S512	M519T	519	Missense	distal	7	no	10.216	9.884	EPSD	ICGC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	O75030	MITF	P27361	MAPK3	S512	R513Q	513	Missense	proximal	1	no	10.216	11.773	EPSD	ICGC;COSMIC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	O75030	MITF	P27361	MAPK3	S515	M519T	519	Missense	distal	4	no	10.739	11.005	EPSD	ICGC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	O75030	MITF	P27361	MAPK3	S515	R513Q	513	Missense	proximal	-2	no	10.739	10.376	EPSD	ICGC;COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	O75030	MITF	P27361	MAPK3	S518	M519T	519	Missense	proximal	1	no	6.543	11.346	EPSD	ICGC	9.358	Gain
CMGC_MAPK_ERK1_MAPK3_ST	P03372	ESR1	P27361	MAPK3	S104	P99S	99	Missense	distal	-5	no	16.662	16.667	EPSD;PhosphoSitePlus	ICGC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P03372	ESR1	P27361	MAPK3	S104	S102N	102	Missense	proximal	-2	no	16.662	15.717	EPSD;PhosphoSitePlus	ICGC;COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P03372	ESR1	P27361	MAPK3	S104	N101S	101	Missense	distal	-3	no	16.662	16.706	EPSD;PhosphoSitePlus	ICGC;COSMIC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P03372	ESR1	P27361	MAPK3	S106	P99S	99	Missense	distal	-7	no	16.212	16.174	EPSD;PhosphoSitePlus	ICGC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P03372	ESR1	P27361	MAPK3	S106	S102N	102	Missense	distal	-4	no	16.212	16.150	EPSD;PhosphoSitePlus	ICGC;COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P03372	ESR1	P27361	MAPK3	S106	N101S	101	Missense	distal	-5	no	16.212	16.252	EPSD;PhosphoSitePlus	ICGC;COSMIC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P03372	ESR1	P27361	MAPK3	S106	H112P	112	Missense	distal	6	no	16.212	16.305	EPSD;PhosphoSitePlus	ICGC;COSMIC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P03372	ESR1	P27361	MAPK3	S118	H112P	112	Missense	distal	-6	no	15.977	16.058	PhosphoSitePlus;EPSD	ICGC;COSMIC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P03372	ESR1	P27361	MAPK3	S118	P114L	114	Missense	distal	-4	no	15.977	15.865	PhosphoSitePlus;EPSD	ICGC;COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P03372	ESR1	P27361	MAPK3	S294	R300L	300	Missense	distal	6	no	14.592	14.477	EPSD	ICGC;COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P03372	ESR1	P27361	MAPK3	S294	R300S	300	Missense	distal	6	no	14.592	14.833	EPSD	ICGC;COSMIC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P03372	ESR1	P27361	MAPK3	S294	R300H	300	Missense	distal	6	no	14.592	14.610	EPSD	ICGC;COSMIC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P03372	ESR1	P27361	MAPK3	S573	S576L	576	Missense	distal	3	no	9.490	9.458	EPSD	ICGC;COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P03372	ESR1	P27361	MAPK3	S575	S576L	576	Missense	proximal	1	no	11.699	11.715	EPSD	ICGC;COSMIC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P03372	ESR1	P27361	MAPK3	S576	S576L	576	Missense	central	0	yes	13.096	0.000	EPSD	ICGC;COSMIC	9.358	Loss
CMGC_MAPK_ERK1_MAPK3_ST	P03372	ESR1	P27361	MAPK3	S578	S576L	576	Missense	proximal	-2	no	10.031	9.723	EPSD	ICGC;COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q13614	MTMR2	P27361	MAPK3	S21	A28D	28	Missense	distal	7	no	10.732	10.493	EPSD	ICGC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q13614	MTMR2	P27361	MAPK3	S21	P14Q	14	Missense	distal	-7	no	10.732	10.777	EPSD	ICGC;COSMIC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q13614	MTMR2	P27361	MAPK3	S21	A28S	28	Missense	distal	7	no	10.732	10.386	EPSD	ICGC;COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q13614	MTMR2	P27361	MAPK3	S26	A28D	28	Missense	proximal	2	no	10.236	10.263	EPSD	ICGC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q13614	MTMR2	P27361	MAPK3	S26	A28S	28	Missense	proximal	2	no	10.236	10.274	EPSD	ICGC;COSMIC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q13614	MTMR2	P27361	MAPK3	S27	A28D	28	Missense	proximal	1	no	10.494	11.132	EPSD	ICGC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q13614	MTMR2	P27361	MAPK3	S27	A28S	28	Missense	proximal	1	no	10.494	10.680	EPSD	ICGC;COSMIC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q13614	MTMR2	P27361	MAPK3	S29	A28D	28	Missense	proximal	-1	no	10.079	10.166	EPSD	ICGC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q13614	MTMR2	P27361	MAPK3	S29	A28S	28	Missense	proximal	-1	no	10.079	10.213	EPSD	ICGC;COSMIC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P41212	ETV6	P27361	MAPK3	T4	C8F	8	Missense	distal	4	no	13.152	13.241	EPSD	ICGC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P41212	ETV6	P27361	MAPK3	S16	P20S	20	Missense	distal	4	no	10.814	10.863	EPSD	ICGC;COSMIC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P41212	ETV6	P27361	MAPK3	S16	P20Q	20	Missense	distal	4	no	10.814	10.672	EPSD	ICGC;COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P41212	ETV6	P27361	MAPK3	S16	E13K	13	Missense	distal	-3	no	10.814	10.783	EPSD	ICGC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P41212	ETV6	P27361	MAPK3	S16	P19S	19	Missense	distal	3	no	10.814	10.809	EPSD	ICGC;COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P41212	ETV6	P27361	MAPK3	S16	S16L	16	Missense	central	0	yes	10.814	0.000	EPSD	ICGC;COSMIC	9.358	Loss
CMGC_MAPK_ERK1_MAPK3_ST	P41212	ETV6	P27361	MAPK3	T18	P20S	20	Missense	proximal	2	no	18.242	18.244	EPSD	ICGC;COSMIC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P41212	ETV6	P27361	MAPK3	T18	P20Q	20	Missense	proximal	2	no	18.242	18.222	EPSD	ICGC;COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P41212	ETV6	P27361	MAPK3	T18	P25L	25	Missense	distal	7	no	18.242	18.434	EPSD	ICGC;COSMIC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P41212	ETV6	P27361	MAPK3	T18	E13K	13	Missense	distal	-5	no	18.242	18.230	EPSD	ICGC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P41212	ETV6	P27361	MAPK3	T18	P19S	19	Missense	proximal	1	no	18.242	9.188	EPSD	ICGC;COSMIC	9.358	Loss
CMGC_MAPK_ERK1_MAPK3_ST	P41212	ETV6	P27361	MAPK3	T18	S16L	16	Missense	proximal	-2	no	18.242	17.933	EPSD	ICGC;COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P41212	ETV6	P27361	MAPK3	S22	P20S	20	Missense	proximal	-2	no	18.707	17.631	EPSD	ICGC;COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P41212	ETV6	P27361	MAPK3	S22	P20Q	20	Missense	proximal	-2	no	18.707	16.943	EPSD	ICGC;COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P41212	ETV6	P27361	MAPK3	S22	P25L	25	Missense	distal	3	no	18.707	18.671	EPSD	ICGC;COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P41212	ETV6	P27361	MAPK3	S22	P19S	19	Missense	distal	-3	no	18.707	18.699	EPSD	ICGC;COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P41212	ETV6	P27361	MAPK3	S22	A28S	28	Missense	distal	6	no	18.707	19.233	EPSD	ICGC;COSMIC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P41212	ETV6	P27361	MAPK3	S22	S16L	16	Missense	distal	-6	no	18.707	18.376	EPSD	ICGC;COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P41212	ETV6	P27361	MAPK3	S26	P20S	20	Missense	distal	-6	no	12.337	12.422	EPSD	ICGC;COSMIC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P41212	ETV6	P27361	MAPK3	S26	P20Q	20	Missense	distal	-6	no	12.337	12.271	EPSD	ICGC;COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P41212	ETV6	P27361	MAPK3	S26	P25L	25	Missense	proximal	-1	no	12.337	12.242	EPSD	ICGC;COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P41212	ETV6	P27361	MAPK3	S26	P19S	19	Missense	distal	-7	no	12.337	12.299	EPSD	ICGC;COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P41212	ETV6	P27361	MAPK3	S26	A28S	28	Missense	proximal	2	no	12.337	12.376	EPSD	ICGC;COSMIC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P41212	ETV6	P27361	MAPK3	S29	P25L	25	Missense	distal	-4	no	9.503	9.390	EPSD	ICGC;COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P41212	ETV6	P27361	MAPK3	S29	A28S	28	Missense	proximal	-1	no	9.503	9.636	EPSD	ICGC;COSMIC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P41212	ETV6	P27361	MAPK3	T31	P25L	25	Missense	distal	-6	no	15.403	15.156	EPSD	ICGC;COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P41212	ETV6	P27361	MAPK3	T31	A28S	28	Missense	distal	-3	no	15.403	15.495	EPSD	ICGC;COSMIC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P41212	ETV6	P27361	MAPK3	T31	V37M	37	Missense	distal	6	no	15.403	15.192	EPSD	ICGC;COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P41212	ETV6	P27361	MAPK3	S131	H135R	135	Missense	distal	4	no	15.976	15.970	EPSD	ICGC;COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P41212	ETV6	P27361	MAPK3	T161	E154D	154	Missense	distal	-7	no	13.998	14.009	EPSD	ICGC;COSMIC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P41212	ETV6	P27361	MAPK3	T161	D155N	155	Missense	distal	-6	no	13.998	13.936	EPSD	ICGC;GDSC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P41212	ETV6	P27361	MAPK3	S184	H190R	190	Missense	distal	6	no	16.650	16.631	EPSD	ICGC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P41212	ETV6	P27361	MAPK3	S184	R191L	191	Missense	distal	7	no	16.650	16.751	EPSD	ICGC;COSMIC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P41212	ETV6	P27361	MAPK3	S184	R183S	183	Missense	proximal	-1	no	16.650	16.692	EPSD	ICGC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P41212	ETV6	P27361	MAPK3	S184	R181H	181	Missense	distal	-3	no	16.650	16.656	EPSD	ICGC;GDSC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P41212	ETV6	P27361	MAPK3	S193	E197K	197	Missense	distal	4	no	16.703	16.665	EPSD	ICGC;COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P41212	ETV6	P27361	MAPK3	S193	H190R	190	Missense	distal	-3	no	16.703	16.697	EPSD	ICGC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P41212	ETV6	P27361	MAPK3	S193	R191L	191	Missense	proximal	-2	no	16.703	16.719	EPSD	ICGC;COSMIC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P41212	ETV6	P27361	MAPK3	S203	R202W	202	Missense	proximal	-1	no	17.076	16.838	EPSD	ICGC;COSMIC;CCLE	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P41212	ETV6	P27361	MAPK3	S203	R210H	210	Missense	distal	7	no	17.076	17.044	EPSD	ICGC;COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P41212	ETV6	P27361	MAPK3	S203	E197K	197	Missense	distal	-6	no	17.076	16.934	EPSD	ICGC;COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P41212	ETV6	P27361	MAPK3	S213	E216K	216	Missense	distal	3	no	15.938	15.928	EPSD;PhosphoSitePlus	ICGC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P41212	ETV6	P27361	MAPK3	S213	R210H	210	Missense	distal	-3	no	15.938	15.945	EPSD;PhosphoSitePlus	ICGC;COSMIC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P41212	ETV6	P27361	MAPK3	S213	Q219H	219	Missense	distal	6	no	15.938	16.027	EPSD;PhosphoSitePlus	ICGC;COSMIC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P41212	ETV6	P27361	MAPK3	S236	P239L	239	Missense	distal	3	no	10.493	10.457	EPSD	ICGC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P41212	ETV6	P27361	MAPK3	S238	P239L	239	Missense	proximal	1	no	17.742	8.704	EPSD	ICGC	9.358	Loss
CMGC_MAPK_ERK1_MAPK3_ST	P41212	ETV6	P27361	MAPK3	S248	E250D	250	Missense	proximal	2	no	9.596	9.593	EPSD	ICGC;COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P41212	ETV6	P27361	MAPK3	S257	R264C	264	Missense	distal	7	no	18.675	19.118	PhosphoSitePlus;EPSD	ICGC;COSMIC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P41212	ETV6	P27361	MAPK3	S257	R264H	264	Missense	distal	7	no	18.675	18.643	PhosphoSitePlus;EPSD	ICGC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P41212	ETV6	P27361	MAPK3	S257	E250D	250	Missense	distal	-7	no	18.675	18.686	PhosphoSitePlus;EPSD	ICGC;COSMIC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P41212	ETV6	P27361	MAPK3	S271	R264C	264	Missense	distal	-7	no	15.378	15.565	EPSD	ICGC;COSMIC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P41212	ETV6	P27361	MAPK3	S271	R264H	264	Missense	distal	-7	no	15.378	15.367	EPSD	ICGC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P41212	ETV6	P27361	MAPK3	S307	E310D	310	Missense	distal	3	no	9.603	9.606	EPSD	ICGC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P41212	ETV6	P27361	MAPK3	S323	E326Q	326	Missense	distal	3	no	16.845	16.836	EPSD	ICGC;COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P41212	ETV6	P27361	MAPK3	T422	G429D	429	Missense	distal	7	no	14.210	14.177	EPSD	ICGC;COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P41212	ETV6	P27361	MAPK3	T422	R418S	418	Missense	distal	-4	no	14.210	14.287	EPSD	ICGC;COSMIC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P41212	ETV6	P27361	MAPK3	T422	L415F	415	Missense	distal	-7	no	14.210	14.285	EPSD	ICGC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P41212	ETV6	P27361	MAPK3	T431	D432H	432	Missense	proximal	1	no	9.143	9.989	EPSD	ICGC;COSMIC	9.358	Gain
CMGC_MAPK_ERK1_MAPK3_ST	P41212	ETV6	P27361	MAPK3	T431	G429D	429	Missense	proximal	-2	no	9.143	9.653	EPSD	ICGC;COSMIC	9.358	Gain
CMGC_MAPK_ERK1_MAPK3_ST	P41212	ETV6	P27361	MAPK3	S439	D432H	432	Missense	distal	-7	no	9.952	9.981	EPSD	ICGC;COSMIC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P41212	ETV6	P27361	MAPK3	S439	E438D	438	Missense	proximal	-1	no	9.952	9.930	EPSD	ICGC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P19419	ELK1	P27361	MAPK3	T133	T133K	133	Missense	central	0	yes	15.764	0.000	EPSD	ICGC	9.358	Loss
CMGC_MAPK_ERK1_MAPK3_ST	P19419	ELK1	P27361	MAPK3	S304	G299S	299	Missense	distal	-5	no	14.893	14.936	EPSD	ICGC;COSMIC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P19419	ELK1	P27361	MAPK3	S304	A297G	297	Missense	distal	-7	no	14.893	14.781	EPSD	ICGC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P19419	ELK1	P27361	MAPK3	S324	S326I	326	Missense	proximal	2	no	17.994	17.959	EPSD	ICGC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P19419	ELK1	P27361	MAPK3	S326	S326I	326	Missense	central	0	yes	9.502	0.000	EPSD	ICGC	9.358	Loss
CMGC_MAPK_ERK1_MAPK3_ST	P19419	ELK1	P27361	MAPK3	T353	P348S	348	Missense	distal	-5	no	14.553	14.558	EPSD	ICGC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P19419	ELK1	P27361	MAPK3	T363	T368K	368	Missense	distal	5	no	16.703	16.686	EPSD	ICGC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P19419	ELK1	P27361	MAPK3	T363	P364L	364	Missense	proximal	1	no	16.703	7.665	EPSD	ICGC;COSMIC	9.358	Loss
CMGC_MAPK_ERK1_MAPK3_ST	P19419	ELK1	P27361	MAPK3	T368	T368K	368	Missense	central	0	yes	13.845	0.000	EPSD	ICGC	9.358	Loss
CMGC_MAPK_ERK1_MAPK3_ST	P19419	ELK1	P27361	MAPK3	T368	P364L	364	Missense	distal	-4	no	13.845	13.732	EPSD	ICGC;COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P19419	ELK1	P27361	MAPK3	T368	S371L	371	Missense	distal	3	no	13.845	13.813	EPSD	ICGC;COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P19419	ELK1	P27361	MAPK3	S383	P390L	390	Missense	distal	7	no	16.736	16.929	EPSD;PhosphoSitePlus	ICGC;COSMIC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P19419	ELK1	P27361	MAPK3	S383	S380R	380	Missense	distal	-3	no	16.736	16.698	EPSD;PhosphoSitePlus	ICGC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P19419	ELK1	P27361	MAPK3	S383	H377N	377	Missense	distal	-6	no	16.736	16.778	EPSD;PhosphoSitePlus	ICGC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P19419	ELK1	P27361	MAPK3	S383	R388H	388	Missense	distal	5	no	16.736	16.772	EPSD;PhosphoSitePlus	ICGC;COSMIC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P19419	ELK1	P27361	MAPK3	S389	P390L	390	Missense	proximal	1	no	16.106	7.068	PhosphoSitePlus;EPSD	ICGC;COSMIC	9.358	Loss
CMGC_MAPK_ERK1_MAPK3_ST	P19419	ELK1	P27361	MAPK3	S389	R388H	388	Missense	proximal	-1	no	16.106	16.108	PhosphoSitePlus;EPSD	ICGC;COSMIC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P12980	LYL1	P27361	MAPK3	S25	A27V	27	Missense	proximal	2	no	18.155	18.168	EPSD	ICGC;COSMIC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P12980	LYL1	P27361	MAPK3	S36	V42M	42	Missense	distal	6	no	17.023	16.812	PhosphoSitePlus	ICGC;COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P12980	LYL1	P27361	MAPK3	S52	R48Q	48	Missense	distal	-4	no	17.100	17.110	EPSD	ICGC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P12980	LYL1	P27361	MAPK3	S52	G50R	50	Missense	proximal	-2	no	17.100	17.817	EPSD	ICGC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P12980	LYL1	P27361	MAPK3	S52	S52L	52	Missense	central	0	yes	17.100	0.000	EPSD	ICGC	9.358	Loss
CMGC_MAPK_ERK1_MAPK3_ST	P12980	LYL1	P27361	MAPK3	S260	G259S	259	Missense	proximal	-1	no	19.473	19.539	EPSD	ICGC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P08047	SP1	P27361	MAPK3	S41	S36L	36	Missense	distal	-5	no	10.038	9.979	EPSD	ICGC;COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P08047	SP1	P27361	MAPK3	S41	S46C	46	Missense	distal	5	no	10.038	9.515	EPSD	ICGC;COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P08047	SP1	P27361	MAPK3	S41	F35L	35	Missense	distal	-6	no	10.038	10.174	EPSD	ICGC;COSMIC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P08047	SP1	P27361	MAPK3	S42	S36L	36	Missense	distal	-6	no	10.411	10.079	EPSD	ICGC;COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P08047	SP1	P27361	MAPK3	S42	S46C	46	Missense	distal	4	no	10.411	9.907	EPSD	ICGC;COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P08047	SP1	P27361	MAPK3	S42	F35L	35	Missense	distal	-7	no	10.411	10.336	EPSD	ICGC;COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P08047	SP1	P27361	MAPK3	S59	S56A	56	Missense	distal	-3	no	16.761	16.670	PhosphoSitePlus;EPSD	ICGC;COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P08047	SP1	P27361	MAPK3	T117	S114Y	114	Missense	distal	-3	no	14.578	14.515	EPSD	ICGC;COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P08047	SP1	P27361	MAPK3	T117	T117I	117	Missense	central	0	yes	14.578	0.000	EPSD	ICGC	9.358	Loss
CMGC_MAPK_ERK1_MAPK3_ST	P08047	SP1	P27361	MAPK3	T278	T285M	285	Missense	distal	7	no	14.656	14.988	EPSD	ICGC;COSMIC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P08047	SP1	P27361	MAPK3	T453	T455R	455	Missense	proximal	2	no	14.945	14.944	EPSD;PhosphoSitePlus	ICGC;COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P08047	SP1	P27361	MAPK3	T453	I451V	451	Missense	proximal	-2	no	14.945	15.129	EPSD;PhosphoSitePlus	ICGC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P08047	SP1	P27361	MAPK3	S588	Q594E	594	Missense	distal	6	no	15.263	15.442	EPSD	ICGC;COSMIC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P08047	SP1	P27361	MAPK3	S588	Q592H	592	Missense	distal	4	no	15.263	15.313	EPSD	ICGC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P08047	SP1	P27361	MAPK3	S588	P589Q	589	Missense	proximal	1	no	15.263	7.319	EPSD	ICGC;COSMIC	9.358	Loss
CMGC_MAPK_ERK1_MAPK3_ST	P08047	SP1	P27361	MAPK3	T739	A738G	738	Missense	proximal	-1	no	15.700	15.767	EPSD;PhosphoSitePlus	ICGC;COSMIC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P55211	CASP9	P27361	MAPK3	S87	Q94K	94	Missense	distal	7	no	12.012	11.988	EPSD	ICGC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P55211	CASP9	P27361	MAPK3	S87	D83E	83	Missense	distal	-4	no	12.012	12.023	EPSD	ICGC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P55211	CASP9	P27361	MAPK3	S87	Q82H	82	Missense	distal	-5	no	12.012	12.029	EPSD	ICGC;COSMIC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P55211	CASP9	P27361	MAPK3	T107	E114V	114	Missense	distal	7	no	14.149	14.362	EPSD	ICGC;COSMIC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P55211	CASP9	P27361	MAPK3	T107	P113Q	113	Missense	distal	6	no	14.149	13.967	EPSD	ICGC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P55211	CASP9	P27361	MAPK3	T125	L121I	121	Missense	distal	-4	no	16.610	16.591	PhosphoSitePlus	ICGC;COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P55211	CASP9	P27361	MAPK3	S302	S302F	302	Missense	central	0	yes	16.569	0.000	EPSD	ICGC	9.358	Loss
CMGC_MAPK_ERK1_MAPK3_ST	P55211	CASP9	P27361	MAPK3	S307	S302F	302	Missense	distal	-5	no	16.881	16.747	EPSD	ICGC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	O43561	LAT	P27361	MAPK3	S35	C29Y	29	Missense	distal	-6	no	10.171	10.477	EPSD	ICGC;COSMIC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	O43561	LAT	P27361	MAPK3	S74	P80S	80	Missense	distal	6	no	9.977	10.107	EPSD	ICGC;COSMIC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	O43561	LAT	P27361	MAPK3	S74	P80T	80	Missense	distal	6	no	9.977	9.952	EPSD	ICGC;COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	O43561	LAT	P27361	MAPK3	S84	P80S	80	Missense	distal	-4	no	17.347	17.374	EPSD	ICGC;COSMIC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	O43561	LAT	P27361	MAPK3	S84	P82L	82	Missense	proximal	-2	no	17.347	15.962	EPSD	ICGC;COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	O43561	LAT	P27361	MAPK3	S84	P80T	80	Missense	distal	-4	no	17.347	17.316	EPSD	ICGC;COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	O43561	LAT	P27361	MAPK3	T94	S96F	96	Missense	proximal	2	no	14.599	14.549	EPSD	ICGC;COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	O43561	LAT	P27361	MAPK3	T94	R98Q	98	Missense	distal	4	no	14.599	14.555	EPSD	ICGC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	O43561	LAT	P27361	MAPK3	S96	S96F	96	Missense	central	0	yes	9.599	0.000	EPSD	ICGC;COSMIC	9.358	Loss
CMGC_MAPK_ERK1_MAPK3_ST	O43561	LAT	P27361	MAPK3	S96	R98Q	98	Missense	proximal	2	no	9.599	9.590	EPSD	ICGC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	O43561	LAT	P27361	MAPK3	S97	R98Q	98	Missense	proximal	1	no	9.104	10.661	EPSD	ICGC	9.358	Gain
CMGC_MAPK_ERK1_MAPK3_ST	O43561	LAT	P27361	MAPK3	S240	E245D	245	Missense	distal	5	no	9.498	9.480	EPSD	ICGC;COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	O43561	LAT	P27361	MAPK3	S240	A237T	237	Missense	distal	-3	no	9.498	9.560	EPSD	ICGC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	O43561	LAT	P27361	MAPK3	S240	P236H	236	Missense	distal	-4	no	9.498	9.463	EPSD	ICGC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	O43561	LAT	P27361	MAPK3	S241	E245D	245	Missense	distal	4	no	10.504	10.485	EPSD	ICGC;COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	O43561	LAT	P27361	MAPK3	S241	A237T	237	Missense	distal	-4	no	10.504	10.578	EPSD	ICGC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	O43561	LAT	P27361	MAPK3	S241	P236H	236	Missense	distal	-5	no	10.504	10.473	EPSD	ICGC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q15788	NCOA1	P27361	MAPK3	S16	P23S	23	Missense	distal	7	no	12.112	12.035	EPSD	ICGC;COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q15788	NCOA1	P27361	MAPK3	S16	P14T	14	Missense	proximal	-2	no	12.112	11.127	EPSD	ICGC;COSMIC;CCLE	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q15788	NCOA1	P27361	MAPK3	S22	P23S	23	Missense	proximal	1	no	17.253	8.199	EPSD	ICGC;COSMIC	9.358	Loss
CMGC_MAPK_ERK1_MAPK3_ST	Q15788	NCOA1	P27361	MAPK3	S22	A28S	28	Missense	distal	6	no	17.253	17.778	EPSD	ICGC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q15788	NCOA1	P27361	MAPK3	S22	D25Y	25	Missense	distal	3	no	17.253	17.233	EPSD	ICGC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q15788	NCOA1	P27361	MAPK3	S97	S102I	102	Missense	distal	5	no	9.649	9.257	EPSD	ICGC	9.358	Loss
CMGC_MAPK_ERK1_MAPK3_ST	Q15788	NCOA1	P27361	MAPK3	S97	V94L	94	Missense	distal	-3	no	9.649	9.646	EPSD	ICGC;COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q15788	NCOA1	P27361	MAPK3	S395	R402P	402	Missense	distal	7	no	14.953	14.861	EPSD	ICGC;COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q15788	NCOA1	P27361	MAPK3	S395	P388H	388	Missense	distal	-7	no	14.953	14.987	EPSD	ICGC;COSMIC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q15788	NCOA1	P27361	MAPK3	S395	R402H	402	Missense	distal	7	no	14.953	14.921	EPSD	ICGC;COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q15788	NCOA1	P27361	MAPK3	S517	I512V	512	Missense	distal	-5	no	16.656	16.674	EPSD	ICGC;COSMIC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q15788	NCOA1	P27361	MAPK3	S569	S571I	571	Missense	proximal	2	no	15.846	15.810	EPSD	ICGC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q15788	NCOA1	P27361	MAPK3	S603	D599H	599	Missense	distal	-4	no	9.461	9.434	EPSD	ICGC;COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q15788	NCOA1	P27361	MAPK3	S620	Y626H	626	Missense	distal	6	no	9.542	9.702	EPSD	ICGC;COSMIC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q15788	NCOA1	P27361	MAPK3	S698	E696D	696	Missense	proximal	-2	no	15.369	15.408	EPSD	ICGC;COSMIC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q15788	NCOA1	P27361	MAPK3	S698	D701Y	701	Missense	distal	3	no	15.369	15.350	EPSD	ICGC;COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q15788	NCOA1	P27361	MAPK3	T763	E757D	757	Missense	distal	-6	no	14.531	14.486	EPSD	ICGC;COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q15788	NCOA1	P27361	MAPK3	T789	P788Q	788	Missense	proximal	-1	no	14.106	14.020	EPSD	ICGC;COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q15788	NCOA1	P27361	MAPK3	T979	A978S	978	Missense	proximal	-1	no	15.913	16.046	EPSD	ICGC;COSMIC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q15788	NCOA1	P27361	MAPK3	T979	A978T	978	Missense	proximal	-1	no	15.913	16.016	EPSD	ICGC;COSMIC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q15788	NCOA1	P27361	MAPK3	S997	L1004F	1004	Missense	distal	7	no	16.555	16.776	EPSD	ICGC;COSMIC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q15788	NCOA1	P27361	MAPK3	S997	A1002S	1002	Missense	distal	5	no	16.555	16.811	EPSD	ICGC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q15788	NCOA1	P27361	MAPK3	S997	P998S	998	Missense	proximal	1	no	16.555	7.502	EPSD	ICGC	9.358	Loss
CMGC_MAPK_ERK1_MAPK3_ST	Q15788	NCOA1	P27361	MAPK3	S999	L1004F	1004	Missense	distal	5	no	15.214	15.060	EPSD	ICGC;COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q15788	NCOA1	P27361	MAPK3	S999	S1006I	1006	Missense	distal	7	no	15.214	15.612	EPSD	ICGC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q15788	NCOA1	P27361	MAPK3	S999	A1002S	1002	Missense	distal	3	no	15.214	15.258	EPSD	ICGC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q15788	NCOA1	P27361	MAPK3	S999	P998S	998	Missense	proximal	-1	no	15.214	15.208	EPSD	ICGC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q15788	NCOA1	P27361	MAPK3	S1006	L1004F	1004	Missense	proximal	-2	no	15.764	14.773	EPSD	ICGC;COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q15788	NCOA1	P27361	MAPK3	S1006	G1010C	1010	Missense	distal	4	no	15.764	15.421	EPSD	ICGC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q15788	NCOA1	P27361	MAPK3	S1006	M1011I	1011	Missense	distal	5	no	15.764	15.762	EPSD	ICGC;COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q15788	NCOA1	P27361	MAPK3	S1006	S1006I	1006	Missense	central	0	yes	15.764	0.000	EPSD	ICGC	9.358	Loss
CMGC_MAPK_ERK1_MAPK3_ST	Q15788	NCOA1	P27361	MAPK3	S1006	V1012F	1012	Missense	distal	6	no	15.764	15.489	EPSD	ICGC;COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q15788	NCOA1	P27361	MAPK3	S1006	A1002S	1002	Missense	distal	-4	no	15.764	15.896	EPSD	ICGC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q15788	NCOA1	P27361	MAPK3	S1006	G1010V	1010	Missense	distal	4	no	15.764	15.702	EPSD	ICGC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q15788	NCOA1	P27361	MAPK3	S1006	P1007S	1007	Missense	proximal	1	no	15.764	6.711	EPSD	ICGC	9.358	Loss
CMGC_MAPK_ERK1_MAPK3_ST	Q15788	NCOA1	P27361	MAPK3	T1026	Q1024E	1024	Missense	proximal	-2	no	13.828	13.946	EPSD	ICGC;COSMIC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q15788	NCOA1	P27361	MAPK3	T1026	T1020M	1020	Missense	distal	-6	no	13.828	13.575	EPSD	ICGC;COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q15788	NCOA1	P27361	MAPK3	T1026	P1027L	1027	Missense	proximal	1	no	13.828	4.790	EPSD	ICGC	9.358	Loss
CMGC_MAPK_ERK1_MAPK3_ST	Q15788	NCOA1	P27361	MAPK3	S1033	P1027L	1027	Missense	distal	-6	no	14.922	14.675	EPSD	ICGC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q15788	NCOA1	P27361	MAPK3	S1033	G1035D	1035	Missense	proximal	2	no	14.922	14.927	EPSD	ICGC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q15788	NCOA1	P27361	MAPK3	S1033	R1029Q	1029	Missense	distal	-4	no	14.922	14.932	EPSD	ICGC;COSMIC;GDSC;CCLE	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q15788	NCOA1	P27361	MAPK3	T1099	G1093V	1093	Missense	distal	-6	no	13.844	13.577	EPSD	ICGC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q15788	NCOA1	P27361	MAPK3	T1099	P1102T	1102	Missense	distal	3	no	13.844	13.826	EPSD	ICGC;COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q15788	NCOA1	P27361	MAPK3	T1179	Y1173F	1173	Missense	distal	-6	no	17.543	17.329	PhosphoSitePlus;EPSD	ICGC;COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q15788	NCOA1	P27361	MAPK3	T1179	S1185C	1185	Missense	distal	6	no	17.543	16.675	PhosphoSitePlus;EPSD	ICGC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q15788	NCOA1	P27361	MAPK3	T1179	P1186S	1186	Missense	distal	7	no	17.543	17.465	PhosphoSitePlus;EPSD	ICGC;COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q15788	NCOA1	P27361	MAPK3	T1179	G1174C	1174	Missense	distal	-5	no	17.543	17.424	PhosphoSitePlus;EPSD	ICGC;COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q15788	NCOA1	P27361	MAPK3	S1185	S1185C	1185	Missense	central	0	yes	16.519	0.000	EPSD;PhosphoSitePlus	ICGC	9.358	Loss
CMGC_MAPK_ERK1_MAPK3_ST	Q15788	NCOA1	P27361	MAPK3	S1185	P1186S	1186	Missense	proximal	1	no	16.519	7.466	EPSD;PhosphoSitePlus	ICGC;COSMIC	9.358	Loss
CMGC_MAPK_ERK1_MAPK3_ST	Q15788	NCOA1	P27361	MAPK3	S1250	P1251S	1251	Missense	proximal	1	no	15.421	6.368	EPSD	ICGC	9.358	Loss
CMGC_MAPK_ERK1_MAPK3_ST	Q15788	NCOA1	P27361	MAPK3	S1250	L1249I	1249	Missense	proximal	-1	no	15.421	15.379	EPSD	ICGC;COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q15788	NCOA1	P27361	MAPK3	T1271	Q1278H	1278	Missense	distal	7	no	16.115	16.053	EPSD	ICGC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q15788	NCOA1	P27361	MAPK3	S1279	Q1278H	1278	Missense	proximal	-1	no	15.028	15.070	EPSD	ICGC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q15788	NCOA1	P27361	MAPK3	T1426	T1421M	1421	Missense	distal	-5	no	20.148	20.045	EPSD	ICGC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q96RK0	CIC	P27361	MAPK3	S12	R17C	17	Missense	distal	5	no	11.236	10.857	EPSD	ICGC;COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q96RK0	CIC	P27361	MAPK3	S12	S12F	12	Missense	central	0	yes	11.236	0.000	EPSD	ICGC;COSMIC	9.358	Loss
CMGC_MAPK_ERK1_MAPK3_ST	Q96RK0	CIC	P27361	MAPK3	S317	V318F	318	Missense	proximal	1	no	7.703	10.912	EPSD	ICGC	9.358	Gain
CMGC_MAPK_ERK1_MAPK3_ST	Q96RK0	CIC	P27361	MAPK3	T583	G580C	580	Missense	distal	-3	no	16.618	16.473	EPSD	ICGC;COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q96RK0	CIC	P27361	MAPK3	S700	G695C	695	Missense	distal	-5	no	15.564	15.446	EPSD	ICGC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q96RK0	CIC	P27361	MAPK3	S700	R696L	696	Missense	distal	-4	no	15.564	15.501	EPSD	ICGC;COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q96RK0	CIC	P27361	MAPK3	S700	N702Y	702	Missense	proximal	2	no	15.564	15.560	EPSD	ICGC;COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q96RK0	CIC	P27361	MAPK3	S739	S734L	734	Missense	distal	-5	no	15.295	15.235	EPSD	ICGC;COSMIC;GDSC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q96RK0	CIC	P27361	MAPK3	S904	Q901H	901	Missense	distal	-3	no	16.255	16.269	EPSD	ICGC;COSMIC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q96RK0	CIC	P27361	MAPK3	S904	V903F	903	Missense	proximal	-1	no	16.255	16.135	EPSD	ICGC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q96RK0	CIC	P27361	MAPK3	S946	G939S	939	Missense	distal	-7	no	16.358	16.320	EPSD	ICGC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q96RK0	CIC	P27361	MAPK3	S946	G939A	939	Missense	distal	-7	no	16.358	16.470	EPSD	ICGC;COSMIC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q96RK0	CIC	P27361	MAPK3	T1145	P1139R	1139	Missense	distal	-6	no	15.413	15.337	EPSD	ICGC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q96RK0	CIC	P27361	MAPK3	S1173	Q1170R	1170	Missense	distal	-3	no	16.957	16.965	EPSD	ICGC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q96RK0	CIC	P27361	MAPK3	S1173	K1179N	1179	Missense	distal	6	no	16.957	16.936	EPSD	ICGC;COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q96RK0	CIC	P27361	MAPK3	S1173	R1171W	1171	Missense	proximal	-2	no	16.957	15.061	EPSD	ICGC;COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q96RK0	CIC	P27361	MAPK3	S1173	P1172A	1172	Missense	proximal	-1	no	16.957	16.818	EPSD	ICGC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q96RK0	CIC	P27361	MAPK3	S1173	P1167H	1167	Missense	distal	-6	no	16.957	16.877	EPSD	ICGC;COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q96RK0	CIC	P27361	MAPK3	T1228	P1233S	1233	Missense	distal	5	no	15.870	15.913	EPSD	ICGC;COSMIC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q96RK0	CIC	P27361	MAPK3	T1228	Q1226K	1226	Missense	proximal	-2	no	15.870	15.294	EPSD	ICGC;COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q96RK0	CIC	P27361	MAPK3	T1240	W1239C	1239	Missense	proximal	-1	no	16.065	16.118	EPSD	ICGC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q96RK0	CIC	P27361	MAPK3	T1240	P1233S	1233	Missense	distal	-7	no	16.065	16.027	EPSD	ICGC;COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q96RK0	CIC	P27361	MAPK3	S1246	W1239C	1239	Missense	distal	-7	no	18.368	18.309	EPSD	ICGC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q96RK0	CIC	P27361	MAPK3	T1291	R1286H	1286	Missense	distal	-5	no	16.488	16.497	EPSD	ICGC;COSMIC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q96RK0	CIC	P27361	MAPK3	S1373	P1372L	1372	Missense	proximal	-1	no	15.892	15.797	EPSD	ICGC;COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q96RK0	CIC	P27361	MAPK3	S1382	S1389F	1389	Missense	distal	7	no	14.315	14.806	EPSD	ICGC;COSMIC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q96RK0	CIC	P27361	MAPK3	S1409	R1415C	1415	Missense	distal	6	no	18.257	17.632	PhosphoSitePlus;EPSD	ICGC;COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q96RK0	CIC	P27361	MAPK3	S1595	P1601S	1601	Missense	distal	6	no	18.888	19.018	EPSD	ICGC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q96RK0	CIC	P27361	MAPK3	S1595	Q1593P	1593	Missense	proximal	-2	no	18.888	20.652	EPSD	ICGC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P61586	RHOA	P27361	MAPK3	S73	P75R	75	Missense	proximal	2	no	11.807	11.796	EPSD	ICGC;COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P61586	RHOA	P27361	MAPK3	S73	Y74D	74	Missense	proximal	1	no	11.807	10.254	EPSD	ICGC;COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P61586	RHOA	P27361	MAPK3	S73	D76G	76	Missense	distal	3	no	11.807	11.802	EPSD	ICGC;COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P61586	RHOA	P27361	MAPK3	S73	L69R	69	Missense	distal	-4	no	11.807	11.870	EPSD	ICGC;COSMIC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P61586	RHOA	P27361	MAPK3	S73	D76V	76	Missense	distal	3	no	11.807	11.780	EPSD	ICGC;COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P61586	RHOA	P27361	MAPK3	S73	D76N	76	Missense	distal	3	no	11.807	11.797	EPSD	ICGC;COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q92793	CREBBP	P27361	MAPK3	S23	F30V	30	Missense	distal	7	no	10.043	9.870	EPSD	ICGC;COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q92793	CREBBP	P27361	MAPK3	S93	N88D	88	Missense	distal	-5	no	16.984	16.989	PhosphoSitePlus	ICGC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q92793	CREBBP	P27361	MAPK3	S121	G126V	126	Missense	distal	5	no	14.842	14.641	EPSD	ICGC;COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q92793	CREBBP	P27361	MAPK3	S121	P122T	122	Missense	proximal	1	no	14.842	5.965	EPSD	ICGC;COSMIC	9.358	Loss
CMGC_MAPK_ERK1_MAPK3_ST	Q92793	CREBBP	P27361	MAPK3	S121	Q125H	125	Missense	distal	4	no	14.842	14.893	EPSD	ICGC;COSMIC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q92793	CREBBP	P27361	MAPK3	S121	S116I	116	Missense	distal	-5	no	14.842	14.748	EPSD	ICGC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q92793	CREBBP	P27361	MAPK3	S124	Q125H	125	Missense	proximal	1	no	9.274	9.462	EPSD	ICGC;COSMIC	9.358	Gain
CMGC_MAPK_ERK1_MAPK3_ST	Q92793	CREBBP	P27361	MAPK3	S274	M267I	267	Missense	distal	-7	no	15.055	15.041	EPSD	ICGC;COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q92793	CREBBP	P27361	MAPK3	S281	Q286H	286	Missense	distal	5	no	10.367	10.405	EPSD	ICGC;COSMIC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q92793	CREBBP	P27361	MAPK3	S745	Q752K	752	Missense	distal	7	no	14.467	14.443	EPSD	ICGC;COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q92793	CREBBP	P27361	MAPK3	S1019	E1016K	1016	Missense	distal	-3	no	9.471	9.439	EPSD	ICGC;COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q92793	CREBBP	P27361	MAPK3	S1578	A1585V	1585	Missense	distal	7	no	9.970	9.942	EPSD	ICGC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q92793	CREBBP	P27361	MAPK3	S2328	P2325Q	2325	Missense	distal	-3	no	9.512	9.458	EPSD	ICGC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q01196	RUNX1	P27361	MAPK3	T18	M25V	25	Missense	distal	7	no	9.446	9.314	EPSD	ICGC	9.358	Loss
CMGC_MAPK_ERK1_MAPK3_ST	Q01196	RUNX1	P27361	MAPK3	S21	M25V	25	Missense	distal	4	no	17.104	17.259	EPSD	ICGC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P49841	GSK3B	P27361	MAPK3	T43	D49E	49	Missense	distal	6	no	15.457	15.502	EPSD;PhosphoSitePlus	ICGC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P49841	GSK3B	P27361	MAPK3	S55	D49E	49	Missense	distal	-6	no	9.327	9.371	EPSD	ICGC	9.358	Gain
CMGC_MAPK_ERK1_MAPK3_ST	P49841	GSK3B	P27361	MAPK3	T275	I270V	270	Missense	distal	-5	no	15.173	15.192	EPSD	ICGC;COSMIC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P49841	GSK3B	P27361	MAPK3	T275	R278K	278	Missense	distal	3	no	15.173	15.171	EPSD	ICGC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P49841	GSK3B	P27361	MAPK3	T275	L273R	273	Missense	proximal	-2	no	15.173	15.157	EPSD	ICGC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P49841	GSK3B	P27361	MAPK3	T275	L273M	273	Missense	proximal	-2	no	15.173	13.803	EPSD	ICGC;COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P49841	GSK3B	P27361	MAPK3	T324	R319H	319	Missense	distal	-5	no	14.724	14.733	EPSD	ICGC;COSMIC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P49841	GSK3B	P27361	MAPK3	T324	A327P	327	Missense	distal	3	no	14.724	14.773	EPSD	ICGC;COSMIC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P49841	GSK3B	P27361	MAPK3	T324	R328L	328	Missense	distal	4	no	14.724	14.667	EPSD	ICGC;COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P49841	GSK3B	P27361	MAPK3	T324	P331L	331	Missense	distal	7	no	14.724	14.917	EPSD	ICGC;COSMIC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P49841	GSK3B	P27361	MAPK3	T324	R328Q	328	Missense	distal	4	no	14.724	14.680	EPSD	ICGC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P49841	GSK3B	P27361	MAPK3	T324	L321M	321	Missense	distal	-3	no	14.724	14.673	EPSD	ICGC;COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P49841	GSK3B	P27361	MAPK3	T390	S389P	389	Missense	proximal	-1	no	13.079	13.084	PhosphoSitePlus;EPSD	ICGC;COSMIC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P49841	GSK3B	P27361	MAPK3	T390	A397T	397	Missense	distal	7	no	13.079	12.851	PhosphoSitePlus;EPSD	ICGC;COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P49841	GSK3B	P27361	MAPK3	T390	R383Q	383	Missense	distal	-7	no	13.079	13.078	PhosphoSitePlus;EPSD	ICGC;COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P49841	GSK3B	P27361	MAPK3	S413	G406R	406	Missense	distal	-7	no	10.872	10.917	EPSD	ICGC;COSMIC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P49841	GSK3B	P27361	MAPK3	S413	S415T	415	Missense	proximal	2	no	10.872	10.861	EPSD	ICGC;COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P49841	GSK3B	P27361	MAPK3	S419	S415T	415	Missense	distal	-4	no	10.386	10.328	EPSD	ICGC;COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q16584	MAP3K11	P27361	MAPK3	S11	W16L	16	Missense	distal	5	no	16.073	16.414	EPSD	ICGC;COSMIC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q16584	MAP3K11	P27361	MAPK3	S11	W16R	16	Missense	distal	5	no	16.073	16.541	EPSD	ICGC;COSMIC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q16584	MAP3K11	P27361	MAPK3	S15	W16L	16	Missense	proximal	1	no	11.096	9.962	EPSD	ICGC;COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q16584	MAP3K11	P27361	MAPK3	S15	W16R	16	Missense	proximal	1	no	11.096	9.499	EPSD	ICGC;COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q16584	MAP3K11	P27361	MAPK3	S35	A42D	42	Missense	distal	7	no	17.686	17.446	EPSD	ICGC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q16584	MAP3K11	P27361	MAPK3	S35	P36H	36	Missense	proximal	1	no	17.686	9.930	EPSD	ICGC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q16584	MAP3K11	P27361	MAPK3	T477	R473H	473	Missense	distal	-4	no	9.843	9.857	EPSD	ICGC;COSMIC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q16584	MAP3K11	P27361	MAPK3	T477	G476R	476	Missense	proximal	-1	no	9.843	9.867	EPSD	ICGC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q16584	MAP3K11	P27361	MAPK3	T477	R472C	472	Missense	distal	-5	no	9.843	9.726	EPSD	ICGC;COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q16584	MAP3K11	P27361	MAPK3	S507	R501H	501	Missense	distal	-6	no	15.795	15.790	EPSD	ICGC;COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q16584	MAP3K11	P27361	MAPK3	S507	P508T	508	Missense	proximal	1	no	15.795	6.917	EPSD	ICGC;COSMIC	9.358	Loss
CMGC_MAPK_ERK1_MAPK3_ST	Q16584	MAP3K11	P27361	MAPK3	S507	L510I	510	Missense	distal	3	no	15.795	15.775	EPSD	ICGC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q16584	MAP3K11	P27361	MAPK3	S524	R529Q	529	Missense	distal	5	no	15.473	15.471	EPSD	ICGC;COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q16584	MAP3K11	P27361	MAPK3	S524	T526A	526	Missense	proximal	2	no	15.473	15.445	EPSD	ICGC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q16584	MAP3K11	P27361	MAPK3	S524	R529P	529	Missense	distal	5	no	15.473	15.573	EPSD	ICGC;COSMIC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q16584	MAP3K11	P27361	MAPK3	S548	A543E	543	Missense	distal	-5	no	14.117	14.181	EPSD	ICGC;COSMIC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q16584	MAP3K11	P27361	MAPK3	S674	P675L	675	Missense	proximal	1	no	16.454	7.416	EPSD	ICGC;COSMIC	9.358	Loss
CMGC_MAPK_ERK1_MAPK3_ST	Q16584	MAP3K11	P27361	MAPK3	S674	R671C	671	Missense	distal	-3	no	16.454	16.314	EPSD	ICGC;COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q16584	MAP3K11	P27361	MAPK3	T677	P675L	675	Missense	proximal	-2	no	17.924	16.540	EPSD	ICGC;COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q16584	MAP3K11	P27361	MAPK3	T677	R671C	671	Missense	distal	-6	no	17.924	17.526	EPSD	ICGC;COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q16584	MAP3K11	P27361	MAPK3	T680	P675L	675	Missense	distal	-5	no	15.975	15.920	EPSD	ICGC;COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q16584	MAP3K11	P27361	MAPK3	T682	P675L	675	Missense	distal	-7	no	15.983	16.090	EPSD	ICGC;COSMIC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q16584	MAP3K11	P27361	MAPK3	S705	L712Q	712	Missense	distal	7	no	17.626	17.556	PhosphoSitePlus;EPSD	ICGC;COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q16584	MAP3K11	P27361	MAPK3	T708	L712Q	712	Missense	distal	4	no	15.274	15.286	EPSD	ICGC;COSMIC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q16584	MAP3K11	P27361	MAPK3	T752	T752A	752	Missense	central	0	yes	18.143	0.000	EPSD	ICGC	9.358	Loss
CMGC_MAPK_ERK1_MAPK3_ST	Q16584	MAP3K11	P27361	MAPK3	T752	G751S	751	Missense	proximal	-1	no	18.143	18.209	EPSD	ICGC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q16584	MAP3K11	P27361	MAPK3	T755	T752A	752	Missense	distal	-3	no	15.926	15.864	EPSD	ICGC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q16584	MAP3K11	P27361	MAPK3	T755	G751S	751	Missense	distal	-4	no	15.926	15.965	EPSD	ICGC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q16584	MAP3K11	P27361	MAPK3	S758	T752A	752	Missense	distal	-6	no	16.235	16.087	EPSD;PhosphoSitePlus	ICGC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q16584	MAP3K11	P27361	MAPK3	S758	G751S	751	Missense	distal	-7	no	16.235	16.197	EPSD;PhosphoSitePlus	ICGC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q16584	MAP3K11	P27361	MAPK3	S780	G785R	785	Missense	distal	5	no	11.080	11.001	EPSD	ICGC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q16584	MAP3K11	P27361	MAPK3	S789	G785R	785	Missense	distal	-4	no	16.353	16.314	EPSD	ICGC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q16584	MAP3K11	P27361	MAPK3	S789	P796T	796	Missense	distal	7	no	16.353	16.394	EPSD	ICGC;COSMIC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q16584	MAP3K11	P27361	MAPK3	S793	P796T	796	Missense	distal	3	no	17.525	17.506	EPSD	ICGC;COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q16584	MAP3K11	P27361	MAPK3	S793	R799S	799	Missense	distal	6	no	17.525	17.766	EPSD	ICGC;COSMIC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q96FF9	CDCA5	P27361	MAPK3	S21	R18S	18	Missense	distal	-3	no	17.568	17.606	EPSD	ICGC;COSMIC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q96FF9	CDCA5	P27361	MAPK3	S21	P20T	20	Missense	proximal	-1	no	17.568	17.532	EPSD	ICGC;COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q96FF9	CDCA5	P27361	MAPK3	T48	P49H	49	Missense	proximal	1	no	17.066	9.310	EPSD	ICGC;COSMIC	9.358	Loss
CMGC_MAPK_ERK1_MAPK3_ST	Q96FF9	CDCA5	P27361	MAPK3	S75	P71S	71	Missense	distal	-4	no	16.138	16.165	EPSD	ICGC;COSMIC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q96FF9	CDCA5	P27361	MAPK3	S75	V70I	70	Missense	distal	-5	no	16.138	16.119	EPSD	ICGC;COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q96FF9	CDCA5	P27361	MAPK3	S79	S83F	83	Missense	distal	4	no	14.812	14.398	EPSD;PhosphoSitePlus	ICGC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q96FF9	CDCA5	P27361	MAPK3	S83	S83F	83	Missense	central	0	yes	10.115	0.000	EPSD	ICGC	9.358	Loss
CMGC_MAPK_ERK1_MAPK3_ST	Q96FF9	CDCA5	P27361	MAPK3	T111	T105K	105	Missense	distal	-6	no	16.827	16.837	EPSD	ICGC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q96FF9	CDCA5	P27361	MAPK3	T159	R163Q	163	Missense	distal	4	no	14.467	14.422	EPSD	ICGC;COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q96FF9	CDCA5	P27361	MAPK3	T159	R162S	162	Missense	distal	3	no	14.467	14.489	EPSD	ICGC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q96FF9	CDCA5	P27361	MAPK3	S209	I208S	208	Missense	proximal	-1	no	14.429	14.560	PhosphoSitePlus;EPSD	ICGC;COSMIC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q96FF9	CDCA5	P27361	MAPK3	S209	T204N	204	Missense	distal	-5	no	14.429	14.404	PhosphoSitePlus;EPSD	ICGC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q96FF9	CDCA5	P27361	MAPK3	S209	P211Q	211	Missense	proximal	2	no	14.429	14.409	PhosphoSitePlus;EPSD	ICGC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q96FF9	CDCA5	P27361	MAPK3	S209	P211T	211	Missense	proximal	2	no	14.429	14.419	PhosphoSitePlus;EPSD	ICGC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q96FF9	CDCA5	P27361	MAPK3	S209	Q215K	215	Missense	distal	6	no	14.429	14.532	PhosphoSitePlus;EPSD	ICGC;COSMIC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P23396	RPS3	P27361	MAPK3	T42	R45S	45	Missense	distal	3	no	15.833	15.855	PhosphoSitePlus	ICGC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P23396	RPS3	P27361	MAPK3	T42	R40Q	40	Missense	proximal	-2	no	15.833	15.469	PhosphoSitePlus	ICGC;COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P23396	RPS3	P27361	MAPK3	T42	G36R	36	Missense	distal	-6	no	15.833	15.735	PhosphoSitePlus	ICGC;COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P23396	RPS3	P27361	MAPK3	S104	A102D	102	Missense	proximal	-2	no	8.708	9.452	EPSD	ICGC;COSMIC	9.358	Gain
CMGC_MAPK_ERK1_MAPK3_ST	P17861	XBP1	P27361	MAPK3	T14	A7T	7	Missense	distal	-7	no	14.755	14.682	EPSD	ICGC;COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P17861	XBP1	P27361	MAPK3	T14	P15R	15	Missense	proximal	1	no	14.755	5.255	EPSD	ICGC;COSMIC	9.358	Loss
CMGC_MAPK_ERK1_MAPK3_ST	P17861	XBP1	P27361	MAPK3	T14	L19F	19	Missense	distal	5	no	14.755	14.602	EPSD	ICGC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P17861	XBP1	P27361	MAPK3	S47	Q43E	43	Missense	distal	-4	no	15.607	15.650	EPSD	ICGC;COSMIC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P17861	XBP1	P27361	MAPK3	S47	R44G	44	Missense	distal	-3	no	15.607	15.613	EPSD	ICGC;COSMIC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P17861	XBP1	P27361	MAPK3	S68	K72R	72	Missense	distal	4	no	17.359	17.351	PhosphoSitePlus;EPSD	ICGC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P17861	XBP1	P27361	MAPK3	S68	Q62L	62	Missense	distal	-6	no	17.359	17.178	PhosphoSitePlus;EPSD	ICGC;COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P17861	XBP1	P27361	MAPK3	S68	R75M	75	Missense	distal	7	no	17.359	17.640	PhosphoSitePlus;EPSD	ICGC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P17861	XBP1	P27361	MAPK3	S68	S68R	68	Missense	central	0	yes	17.359	0.000	PhosphoSitePlus;EPSD	ICGC	9.358	Loss
CMGC_MAPK_ERK1_MAPK3_ST	P17861	XBP1	P27361	MAPK3	S68	E71K	71	Missense	distal	3	no	17.359	17.348	PhosphoSitePlus;EPSD	ICGC;COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P17861	XBP1	P27361	MAPK3	S68	L74P	74	Missense	distal	6	no	17.359	17.585	PhosphoSitePlus;EPSD	ICGC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P17861	XBP1	P27361	MAPK3	S68	R61Q	61	Missense	distal	-7	no	17.359	17.358	PhosphoSitePlus;EPSD	ICGC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P17861	XBP1	P27361	MAPK3	S68	E71D	71	Missense	distal	3	no	17.359	17.361	PhosphoSitePlus;EPSD	ICGC;COSMIC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P17861	XBP1	P27361	MAPK3	S181	Q174R	174	Missense	distal	-7	no	16.372	16.373	EPSD;PhosphoSitePlus	ICGC;COSMIC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P17861	XBP1	P27361	MAPK3	S181	A178D	178	Missense	distal	-3	no	16.372	16.441	EPSD;PhosphoSitePlus	ICGC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P17861	XBP1	P27361	MAPK3	S181	P182H	182	Missense	proximal	1	no	16.372	8.616	EPSD;PhosphoSitePlus	ICGC	9.358	Loss
CMGC_MAPK_ERK1_MAPK3_ST	P17861	XBP1	P27361	MAPK3	S181	S187F	187	Missense	distal	6	no	16.372	15.658	EPSD;PhosphoSitePlus	ICGC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P17861	XBP1	P27361	MAPK3	S181	A178S	178	Missense	distal	-3	no	16.372	16.463	EPSD;PhosphoSitePlus	ICGC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P17861	XBP1	P27361	MAPK3	S255	H252Y	252	Missense	distal	-3	no	10.729	10.698	EPSD	ICGC;COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q8IZP0	ABI1	P27361	MAPK3	S22	A18E	18	Missense	distal	-4	no	10.338	10.445	EPSD	ICGC;COSMIC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q8IZP0	ABI1	P27361	MAPK3	S183	P176L	176	Missense	distal	-7	no	18.665	18.772	EPSD;PhosphoSitePlus	ICGC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q8IZP0	ABI1	P27361	MAPK3	S410	P411T	411	Missense	proximal	1	no	16.907	8.030	PhosphoSitePlus;EPSD	ICGC;COSMIC	9.358	Loss
CMGC_MAPK_ERK1_MAPK3_ST	P35658	NUP214	P27361	MAPK3	S30	P31R	31	Missense	proximal	1	no	15.068	5.567	EPSD	ICGC	9.358	Loss
CMGC_MAPK_ERK1_MAPK3_ST	P35658	NUP214	P27361	MAPK3	S201	L207P	207	Missense	distal	6	no	15.156	15.382	EPSD	ICGC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P35658	NUP214	P27361	MAPK3	S268	V272L	272	Missense	distal	4	no	15.272	15.292	EPSD	ICGC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P35658	NUP214	P27361	MAPK3	S268	P269Q	269	Missense	proximal	1	no	15.272	7.328	EPSD	ICGC;COSMIC	9.358	Loss
CMGC_MAPK_ERK1_MAPK3_ST	P35658	NUP214	P27361	MAPK3	T437	A443T	443	Missense	distal	6	no	16.689	17.059	EPSD	ICGC;COSMIC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P35658	NUP214	P27361	MAPK3	S440	A443T	443	Missense	distal	3	no	9.966	9.997	EPSD	ICGC;COSMIC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P35658	NUP214	P27361	MAPK3	S462	A468S	468	Missense	distal	6	no	16.511	17.036	EPSD	ICGC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P35658	NUP214	P27361	MAPK3	S462	S457C	457	Missense	distal	-5	no	16.511	16.349	EPSD	ICGC;COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P35658	NUP214	P27361	MAPK3	S483	K490N	490	Missense	distal	7	no	10.983	10.974	EPSD	ICGC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P35658	NUP214	P27361	MAPK3	S483	G476C	476	Missense	distal	-7	no	10.983	11.215	EPSD	ICGC;COSMIC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P35658	NUP214	P27361	MAPK3	S501	S508I	508	Missense	distal	7	no	12.628	13.026	EPSD	ICGC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P35658	NUP214	P27361	MAPK3	T519	P515S	515	Missense	distal	-4	no	11.920	11.947	EPSD	ICGC;COSMIC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P35658	NUP214	P27361	MAPK3	T533	P532L	532	Missense	proximal	-1	no	14.038	13.943	EPSD	ICGC;GDSC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P35658	NUP214	P27361	MAPK3	S537	P532L	532	Missense	distal	-5	no	15.176	15.122	EPSD	ICGC;GDSC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P35658	NUP214	P27361	MAPK3	S547	S545L	545	Missense	proximal	-2	no	12.827	12.519	EPSD	ICGC;COSMIC;GDSC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P35658	NUP214	P27361	MAPK3	T598	A594T	594	Missense	distal	-4	no	15.639	15.713	EPSD	ICGC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P35658	NUP214	P27361	MAPK3	S625	P629L	629	Missense	distal	4	no	9.540	9.386	EPSD	ICGC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P35658	NUP214	P27361	MAPK3	T628	S635I	635	Missense	distal	7	no	14.879	15.277	EPSD	ICGC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P35658	NUP214	P27361	MAPK3	T628	P629L	629	Missense	proximal	1	no	14.879	5.841	EPSD	ICGC	9.358	Loss
CMGC_MAPK_ERK1_MAPK3_ST	P35658	NUP214	P27361	MAPK3	T1134	A1138T	1138	Missense	distal	4	no	15.218	15.436	EPSD	ICGC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P35658	NUP214	P27361	MAPK3	S1136	A1138T	1138	Missense	proximal	2	no	9.690	9.718	EPSD	ICGC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P35658	NUP214	P27361	MAPK3	T1150	Y1145F	1145	Missense	distal	-5	no	15.675	15.605	EPSD	ICGC;COSMIC;GDSC;CCLE	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P35658	NUP214	P27361	MAPK3	T1178	A1180T	1180	Missense	proximal	2	no	12.304	12.331	EPSD	ICGC;COSMIC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P35658	NUP214	P27361	MAPK3	T1178	A1180S	1180	Missense	proximal	2	no	12.304	12.343	EPSD	ICGC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P35658	NUP214	P27361	MAPK3	S1272	G1276E	1276	Missense	distal	4	no	16.201	16.262	EPSD	ICGC;COSMIC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P35658	NUP214	P27361	MAPK3	S1809	G1816D	1816	Missense	distal	7	no	15.741	15.708	PhosphoSitePlus;EPSD	ICGC;COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P35658	NUP214	P27361	MAPK3	S1809	A1803T	1803	Missense	distal	-6	no	15.741	15.889	PhosphoSitePlus;EPSD	ICGC;COSMIC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P35658	NUP214	P27361	MAPK3	S1809	P1804H	1804	Missense	distal	-5	no	15.741	15.710	PhosphoSitePlus;EPSD	ICGC;COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P35658	NUP214	P27361	MAPK3	T1946	G1951E	1951	Missense	distal	5	no	10.439	10.479	EPSD	ICGC;COSMIC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P35658	NUP214	P27361	MAPK3	S1963	G1969V	1969	Missense	distal	6	no	17.142	16.936	EPSD	ICGC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P35658	NUP214	P27361	MAPK3	S1978	G1977V	1977	Missense	proximal	-1	no	15.610	15.592	EPSD	ICGC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P35658	NUP214	P27361	MAPK3	S1978	P1980H	1980	Missense	proximal	2	no	15.610	15.597	EPSD	ICGC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P35658	NUP214	P27361	MAPK3	T1981	G1977V	1977	Missense	distal	-4	no	10.100	9.987	EPSD	ICGC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P35658	NUP214	P27361	MAPK3	T1981	P1980H	1980	Missense	proximal	-1	no	10.100	10.055	EPSD	ICGC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P35658	NUP214	P27361	MAPK3	S1985	P1980H	1980	Missense	distal	-5	no	14.286	14.254	EPSD	ICGC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P35658	NUP214	P27361	MAPK3	S2002	G2008A	2008	Missense	distal	6	no	16.922	16.629	EPSD	ICGC;COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q15672	TWIST1	P27361	MAPK3	S20	E22Q	22	Missense	proximal	2	no	9.358	9.345	EPSD	ICGC;COSMIC	9.358	Loss
CMGC_MAPK_ERK1_MAPK3_ST	Q15672	TWIST1	P27361	MAPK3	S68	P66L	66	Missense	proximal	-2	no	17.779	16.395	PhosphoSitePlus	ICGC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q15672	TWIST1	P27361	MAPK3	S68	G67A	67	Missense	proximal	-1	no	17.779	17.712	PhosphoSitePlus	ICGC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q15672	TWIST1	P27361	MAPK3	S99	G92S	92	Missense	distal	-7	no	17.724	17.686	EPSD	ICGC;COSMIC;CCLE	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q15672	TWIST1	P27361	MAPK3	S99	S93G	93	Missense	distal	-6	no	17.724	17.661	EPSD	ICGC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q15672	TWIST1	P27361	MAPK3	S99	S95G	95	Missense	distal	-4	no	17.724	17.685	EPSD	ICGC;COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q15672	TWIST1	P27361	MAPK3	S102	S95G	95	Missense	distal	-7	no	10.246	10.284	EPSD	ICGC;COSMIC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P28562	DUSP1	P27361	MAPK3	T141	L147I	147	Missense	distal	6	no	12.707	12.494	EPSD	ICGC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P28562	DUSP1	P27361	MAPK3	T141	P142T	142	Missense	proximal	1	no	12.707	3.830	EPSD	ICGC;COSMIC	9.358	Loss
CMGC_MAPK_ERK1_MAPK3_ST	P28562	DUSP1	P27361	MAPK3	S323	A319E	319	Missense	distal	-4	no	14.525	14.633	EPSD	ICGC;COSMIC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P28562	DUSP1	P27361	MAPK3	S323	D330E	330	Missense	distal	7	no	14.525	14.523	EPSD	ICGC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P28562	DUSP1	P27361	MAPK3	S359	S352R	352	Missense	distal	-7	no	18.543	18.626	EPSD;PhosphoSitePlus	ICGC;COSMIC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q92974	ARHGEF2	P27361	MAPK3	S163	R169L	169	Missense	distal	6	no	16.999	16.884	EPSD	ICGC;COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q92974	ARHGEF2	P27361	MAPK3	S172	R169L	169	Missense	distal	-3	no	9.741	9.703	EPSD	ICGC;COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q92974	ARHGEF2	P27361	MAPK3	S932	E935K	935	Missense	distal	3	no	14.564	14.553	EPSD	ICGC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q15796	SMAD2	P27361	MAPK3	T8	P9Q	9	Missense	proximal	1	no	15.951	8.007	EPSD;PhosphoSitePlus	ICGC	9.358	Loss
CMGC_MAPK_ERK1_MAPK3_ST	Q15796	SMAD2	P27361	MAPK3	T8	F7L	7	Missense	proximal	-1	no	15.951	16.066	EPSD;PhosphoSitePlus	ICGC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q15796	SMAD2	P27361	MAPK3	S47	K53N	53	Missense	distal	6	no	9.541	9.520	EPSD	ICGC;COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q15796	SMAD2	P27361	MAPK3	T172	P173Q	173	Missense	proximal	1	no	13.836	5.892	EPSD	ICGC;COSMIC	9.358	Loss
CMGC_MAPK_ERK1_MAPK3_ST	Q15796	SMAD2	P27361	MAPK3	T220	T220K	220	Missense	central	0	yes	15.000	0.000	EPSD;PhosphoSitePlus	ICGC	9.358	Loss
CMGC_MAPK_ERK1_MAPK3_ST	Q15796	SMAD2	P27361	MAPK3	S250	V257F	257	Missense	distal	7	no	17.689	17.862	EPSD;PhosphoSitePlus	ICGC;COSMIC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q15796	SMAD2	P27361	MAPK3	S255	V257F	257	Missense	proximal	2	no	18.277	18.253	PhosphoSitePlus;EPSD	ICGC;COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q15796	SMAD2	P27361	MAPK3	S417	R415I	415	Missense	proximal	-2	no	9.485	9.046	EPSD	ICGC;COSMIC	9.358	Loss
CMGC_MAPK_ERK1_MAPK3_ST	P16144	ITGB4	P27361	MAPK3	S19	S19G	19	Missense	central	0	yes	10.849	0.000	EPSD	ICGC;COSMIC	9.358	Loss
CMGC_MAPK_ERK1_MAPK3_ST	P16144	ITGB4	P27361	MAPK3	S99	R97W	97	Missense	proximal	-2	no	9.797	7.900	EPSD	ICGC;COSMIC	9.358	Loss
CMGC_MAPK_ERK1_MAPK3_ST	P16144	ITGB4	P27361	MAPK3	S99	R98H	98	Missense	proximal	-1	no	9.797	9.799	EPSD	ICGC;CCLE	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P16144	ITGB4	P27361	MAPK3	S99	R98C	98	Missense	proximal	-1	no	9.797	9.612	EPSD	ICGC;COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P16144	ITGB4	P27361	MAPK3	S99	S102F	102	Missense	distal	3	no	9.797	9.732	EPSD	ICGC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P16144	ITGB4	P27361	MAPK3	S102	R109H	109	Missense	distal	7	no	16.331	16.299	EPSD	ICGC;COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P16144	ITGB4	P27361	MAPK3	S102	R97W	97	Missense	distal	-5	no	16.331	16.177	EPSD	ICGC;COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P16144	ITGB4	P27361	MAPK3	S102	R98H	98	Missense	distal	-4	no	16.331	16.345	EPSD	ICGC;CCLE	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P16144	ITGB4	P27361	MAPK3	S102	R109C	109	Missense	distal	7	no	16.331	16.773	EPSD	ICGC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P16144	ITGB4	P27361	MAPK3	S102	R98C	98	Missense	distal	-4	no	16.331	16.170	EPSD	ICGC;COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P16144	ITGB4	P27361	MAPK3	S102	S102F	102	Missense	central	0	yes	16.331	0.000	EPSD	ICGC	9.358	Loss
CMGC_MAPK_ERK1_MAPK3_ST	P16144	ITGB4	P27361	MAPK3	S128	V122A	122	Missense	distal	-6	no	15.588	15.601	EPSD	ICGC;COSMIC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P16144	ITGB4	P27361	MAPK3	S202	P200L	200	Missense	proximal	-2	no	12.834	11.450	EPSD	ICGC;GDSC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P16144	ITGB4	P27361	MAPK3	S377	R373L	373	Missense	distal	-4	no	17.332	17.269	EPSD	ICGC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P16144	ITGB4	P27361	MAPK3	S397	K392E	392	Missense	distal	-5	no	9.948	9.960	EPSD	ICGC;COSMIC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P16144	ITGB4	P27361	MAPK3	S397	R402Q	402	Missense	distal	5	no	9.948	9.946	EPSD	ICGC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P16144	ITGB4	P27361	MAPK3	S397	R402L	402	Missense	distal	5	no	9.948	9.821	EPSD	ICGC;COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P16144	ITGB4	P27361	MAPK3	S397	G396W	396	Missense	proximal	-1	no	9.948	9.734	EPSD	ICGC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P16144	ITGB4	P27361	MAPK3	S397	T395N	395	Missense	proximal	-2	no	9.948	8.913	EPSD	ICGC	9.358	Loss
CMGC_MAPK_ERK1_MAPK3_ST	P16144	ITGB4	P27361	MAPK3	T776	T776M	776	Missense	central	0	yes	16.164	0.000	EPSD	ICGC	9.358	Loss
CMGC_MAPK_ERK1_MAPK3_ST	P16144	ITGB4	P27361	MAPK3	S1119	P1121S	1121	Missense	proximal	2	no	9.619	9.621	EPSD	ICGC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P16144	ITGB4	P27361	MAPK3	S1345	S1350I	1350	Missense	distal	5	no	10.061	9.668	EPSD	ICGC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P16144	ITGB4	P27361	MAPK3	S1356	S1350I	1350	Missense	distal	-6	no	16.245	15.847	PhosphoSitePlus	ICGC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P16144	ITGB4	P27361	MAPK3	S1360	S1366P	1366	Missense	distal	6	no	10.739	10.609	EPSD	ICGC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P16144	ITGB4	P27361	MAPK3	T1434	S1428L	1428	Missense	distal	-6	no	14.846	14.514	EPSD	ICGC;COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	O95817	BAG3	P27361	MAPK3	S7	A3S	3	Missense	distal	-4	no	16.326	16.458	EPSD	ICGC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	O95817	BAG3	P27361	MAPK3	S7	V12L	12	Missense	distal	5	no	16.326	16.322	EPSD	ICGC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	O95817	BAG3	P27361	MAPK3	S65	E72V	72	Missense	distal	7	no	11.121	11.334	EPSD	ICGC;COSMIC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	O95817	BAG3	P27361	MAPK3	S136	R139W	139	Missense	distal	3	no	15.572	15.494	EPSD	ICGC;COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	O95817	BAG3	P27361	MAPK3	S136	M141I	141	Missense	distal	5	no	15.572	15.570	EPSD	ICGC;COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	O95817	BAG3	P27361	MAPK3	S136	E143V	143	Missense	distal	7	no	15.572	15.786	EPSD	ICGC;COSMIC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	O95817	BAG3	P27361	MAPK3	S136	S134F	134	Missense	proximal	-2	no	15.572	14.272	EPSD	ICGC;COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	O95817	BAG3	P27361	MAPK3	S173	P174Q	174	Missense	proximal	1	no	15.221	7.277	EPSD	ICGC;COSMIC	9.358	Loss
CMGC_MAPK_ERK1_MAPK3_ST	O95817	BAG3	P27361	MAPK3	S183	S185L	185	Missense	proximal	2	no	9.410	9.387	EPSD	ICGC;COSMIC;GDSC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	O95817	BAG3	P27361	MAPK3	S264	A262V	262	Missense	proximal	-2	no	13.797	14.494	EPSD	ICGC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	O95817	BAG3	P27361	MAPK3	S264	R261L	261	Missense	distal	-3	no	13.797	13.759	EPSD	ICGC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	O95817	BAG3	P27361	MAPK3	S279	S274L	274	Missense	distal	-5	no	16.045	15.985	EPSD	ICGC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	O95817	BAG3	P27361	MAPK3	S279	T285M	285	Missense	distal	6	no	16.045	15.550	EPSD	ICGC;COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	O95817	BAG3	P27361	MAPK3	S284	T285M	285	Missense	proximal	1	no	9.560	4.758	EPSD	ICGC;COSMIC	9.358	Loss
CMGC_MAPK_ERK1_MAPK3_ST	O95817	BAG3	P27361	MAPK3	T285	T285M	285	Missense	central	0	yes	16.402	0.000	PhosphoSitePlus;EPSD	ICGC;COSMIC	9.358	Loss
CMGC_MAPK_ERK1_MAPK3_ST	O95817	BAG3	P27361	MAPK3	S289	R294C	294	Missense	distal	5	no	16.568	16.189	EPSD;PhosphoSitePlus	ICGC;COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	O95817	BAG3	P27361	MAPK3	S289	T285M	285	Missense	distal	-4	no	16.568	16.447	EPSD;PhosphoSitePlus	ICGC;COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	O95817	BAG3	P27361	MAPK3	S291	R294C	294	Missense	distal	3	no	17.901	17.837	EPSD	ICGC;COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	O95817	BAG3	P27361	MAPK3	S291	V298L	298	Missense	distal	7	no	17.901	17.853	EPSD	ICGC;COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	O95817	BAG3	P27361	MAPK3	S291	T285M	285	Missense	distal	-6	no	17.901	17.647	EPSD	ICGC;COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	O95817	BAG3	P27361	MAPK3	S386	A391S	391	Missense	distal	5	no	17.196	17.451	EPSD	ICGC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	O95817	BAG3	P27361	MAPK3	S386	P387L	387	Missense	proximal	1	no	17.196	8.158	EPSD	ICGC;COSMIC	9.358	Loss
CMGC_MAPK_ERK1_MAPK3_ST	O95817	BAG3	P27361	MAPK3	T406	P407L	407	Missense	proximal	1	no	13.749	4.711	EPSD	ICGC;COSMIC	9.358	Loss
CMGC_MAPK_ERK1_MAPK3_ST	O95817	BAG3	P27361	MAPK3	T406	P410A	410	Missense	distal	4	no	13.749	13.467	EPSD	ICGC;COSMIC;GDSC;CCLE	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P20339	RAB5A	P27361	MAPK3	S123	I128L	128	Missense	distal	5	no	14.916	15.038	PhosphoSitePlus	ICGC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P20339	RAB5A	P27361	MAPK3	S123	K116N	116	Missense	distal	-7	no	14.916	14.900	PhosphoSitePlus	ICGC;COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q15648	MED1	P27361	MAPK3	T212	P213A	213	Missense	proximal	1	no	15.272	6.032	EPSD	ICGC;COSMIC	9.358	Loss
CMGC_MAPK_ERK1_MAPK3_ST	Q15648	MED1	P27361	MAPK3	T212	R214K	214	Missense	proximal	2	no	15.272	15.268	EPSD	ICGC;COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q15648	MED1	P27361	MAPK3	S434	L437R	437	Missense	distal	3	no	15.651	15.661	EPSD	ICGC;COSMIC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q15648	MED1	P27361	MAPK3	T522	Q519H	519	Missense	distal	-3	no	13.472	13.486	EPSD	ICGC;COSMIC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q15648	MED1	P27361	MAPK3	S545	K538N	538	Missense	distal	-7	no	15.497	15.481	EPSD	ICGC;COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q15648	MED1	P27361	MAPK3	T562	M557V	557	Missense	distal	-5	no	15.389	15.432	EPSD	ICGC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q15648	MED1	P27361	MAPK3	T562	P568L	568	Missense	distal	6	no	15.389	15.162	EPSD	ICGC;COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q15648	MED1	P27361	MAPK3	S675	P676S	676	Missense	proximal	1	no	16.204	7.150	EPSD	ICGC;COSMIC	9.358	Loss
CMGC_MAPK_ERK1_MAPK3_ST	Q15648	MED1	P27361	MAPK3	S675	P676L	676	Missense	proximal	1	no	16.204	7.166	EPSD	ICGC;COSMIC	9.358	Loss
CMGC_MAPK_ERK1_MAPK3_ST	Q15648	MED1	P27361	MAPK3	T747	P749L	749	Missense	proximal	2	no	11.840	11.819	EPSD	ICGC;COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q15648	MED1	P27361	MAPK3	T747	P748R	748	Missense	proximal	1	no	11.840	2.340	EPSD	ICGC	9.358	Loss
CMGC_MAPK_ERK1_MAPK3_ST	Q15648	MED1	P27361	MAPK3	T805	P801Q	801	Missense	distal	-4	no	15.425	15.385	EPSD	ICGC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q15648	MED1	P27361	MAPK3	T805	I803V	803	Missense	proximal	-2	no	15.425	15.609	EPSD	ICGC;COSMIC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q15648	MED1	P27361	MAPK3	S887	D891Y	891	Missense	distal	4	no	9.678	9.582	EPSD	ICGC;COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q15648	MED1	P27361	MAPK3	S1045	T1051I	1051	Missense	distal	6	no	9.698	9.283	EPSD	ICGC;COSMIC	9.358	Loss
CMGC_MAPK_ERK1_MAPK3_ST	Q15648	MED1	P27361	MAPK3	T1051	T1051I	1051	Missense	central	0	yes	14.190	0.000	EPSD	ICGC;COSMIC	9.358	Loss
CMGC_MAPK_ERK1_MAPK3_ST	Q15648	MED1	P27361	MAPK3	T1057	T1051I	1051	Missense	distal	-6	no	14.005	13.775	EPSD	ICGC;COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q15648	MED1	P27361	MAPK3	T1057	T1064A	1064	Missense	distal	7	no	14.005	14.233	EPSD	ICGC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q15648	MED1	P27361	MAPK3	S1156	L1163P	1163	Missense	distal	7	no	16.897	16.705	EPSD	ICGC;COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q15648	MED1	P27361	MAPK3	S1156	H1161N	1161	Missense	distal	5	no	16.897	16.883	EPSD	ICGC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q15648	MED1	P27361	MAPK3	S1192	S1192F	1192	Missense	central	0	yes	14.651	0.000	EPSD	ICGC;GDSC;CCLE	9.358	Loss
CMGC_MAPK_ERK1_MAPK3_ST	Q15648	MED1	P27361	MAPK3	S1207	P1208Q	1208	Missense	proximal	1	no	14.894	6.950	EPSD	ICGC	9.358	Loss
CMGC_MAPK_ERK1_MAPK3_ST	Q15648	MED1	P27361	MAPK3	T1215	T1215N	1215	Missense	central	0	yes	16.152	0.000	EPSD	ICGC;COSMIC	9.358	Loss
CMGC_MAPK_ERK1_MAPK3_ST	Q15648	MED1	P27361	MAPK3	T1215	P1208Q	1208	Missense	distal	-7	no	16.152	16.196	EPSD	ICGC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q15648	MED1	P27361	MAPK3	S1223	P1224L	1224	Missense	proximal	1	no	15.688	6.650	EPSD	ICGC;COSMIC	9.358	Loss
CMGC_MAPK_ERK1_MAPK3_ST	Q15648	MED1	P27361	MAPK3	S1272	T1267M	1267	Missense	distal	-5	no	10.362	10.259	EPSD	ICGC;COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q15648	MED1	P27361	MAPK3	S1272	S1269F	1269	Missense	distal	-3	no	10.362	10.220	EPSD	ICGC;COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q15648	MED1	P27361	MAPK3	S1294	P1301Q	1301	Missense	distal	7	no	15.910	16.032	EPSD	ICGC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q15648	MED1	P27361	MAPK3	S1294	S1294C	1294	Missense	central	0	yes	15.910	0.000	EPSD	ICGC;COSMIC	9.358	Loss
CMGC_MAPK_ERK1_MAPK3_ST	Q15648	MED1	P27361	MAPK3	S1433	S1433P	1433	Missense	central	0	yes	17.484	0.000	EPSD	ICGC	9.358	Loss
CMGC_MAPK_ERK1_MAPK3_ST	Q15648	MED1	P27361	MAPK3	S1433	S1437R	1437	Missense	distal	4	no	17.484	17.338	EPSD	ICGC;COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q15648	MED1	P27361	MAPK3	T1440	S1433P	1433	Missense	distal	-7	no	13.736	13.774	EPSD	ICGC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q15648	MED1	P27361	MAPK3	T1440	S1437R	1437	Missense	distal	-3	no	13.736	13.698	EPSD	ICGC;COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q15648	MED1	P27361	MAPK3	T1457	E1464K	1464	Missense	distal	7	no	14.176	14.247	PhosphoSitePlus;EPSD	ICGC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q15648	MED1	P27361	MAPK3	S1532	S1539C	1539	Missense	distal	7	no	9.482	10.094	EPSD	ICGC;COSMIC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q15648	MED1	P27361	MAPK3	S1532	S1525Y	1525	Missense	distal	-7	no	9.482	9.600	EPSD	ICGC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q15648	MED1	P27361	MAPK3	S1536	S1539C	1539	Missense	distal	3	no	17.958	17.873	EPSD	ICGC;COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q15648	MED1	P27361	MAPK3	S1558	D1555E	1555	Missense	distal	-3	no	10.298	10.301	EPSD	ICGC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q15648	MED1	P27361	MAPK3	S1558	S1561R	1561	Missense	distal	3	no	10.298	10.276	EPSD	ICGC;COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q15648	MED1	P27361	MAPK3	S1561	D1555E	1555	Missense	distal	-6	no	17.939	17.983	EPSD	ICGC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q15648	MED1	P27361	MAPK3	S1561	S1561R	1561	Missense	central	0	yes	17.939	0.000	EPSD	ICGC;COSMIC	9.358	Loss
CMGC_MAPK_ERK1_MAPK3_ST	O75582	RPS6KA5	P27361	MAPK3	S376	P380L	380	Missense	distal	4	no	9.775	9.621	EPSD	ICGC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	O75582	RPS6KA5	P27361	MAPK3	S628	L629F	629	Missense	proximal	1	no	6.967	9.791	EPSD	ICGC;COSMIC	9.358	Gain
CMGC_MAPK_ERK1_MAPK3_ST	O75582	RPS6KA5	P27361	MAPK3	T700	P697H	697	Missense	distal	-3	no	16.688	16.648	EPSD	ICGC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	O75582	RPS6KA5	P27361	MAPK3	S768	T774N	774	Missense	distal	6	no	9.457	9.382	EPSD	ICGC;COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	O75582	RPS6KA5	P27361	MAPK3	S770	T774N	774	Missense	distal	4	no	10.362	10.328	EPSD	ICGC;COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	O75582	RPS6KA5	P27361	MAPK3	T775	T774N	774	Missense	proximal	-1	no	17.486	17.468	EPSD	ICGC;COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P29590	PML	P27361	MAPK3	S387	S388Y	388	Missense	proximal	1	no	7.983	9.988	EPSD	ICGC;COSMIC	9.358	Gain
CMGC_MAPK_ERK1_MAPK3_ST	P29590	PML	P27361	MAPK3	S387	S388F	388	Missense	proximal	1	no	7.983	10.822	EPSD	ICGC;COSMIC	9.358	Gain
CMGC_MAPK_ERK1_MAPK3_ST	P29590	PML	P27361	MAPK3	S403	P410A	410	Missense	distal	7	no	15.600	15.868	EPSD	ICGC;COSMIC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P29590	PML	P27361	MAPK3	S403	V398L	398	Missense	distal	-5	no	15.600	15.616	EPSD	ICGC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P29590	PML	P27361	MAPK3	S403	A407S	407	Missense	distal	4	no	15.600	15.931	EPSD	ICGC;COSMIC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P29590	PML	P27361	MAPK3	S403	A407T	407	Missense	distal	4	no	15.600	15.818	EPSD	ICGC;COSMIC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P29590	PML	P27361	MAPK3	T409	P410A	410	Missense	proximal	1	no	14.911	5.671	EPSD	ICGC;COSMIC	9.358	Loss
CMGC_MAPK_ERK1_MAPK3_ST	P29590	PML	P27361	MAPK3	T409	A407S	407	Missense	proximal	-2	no	14.911	16.186	EPSD	ICGC;COSMIC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P29590	PML	P27361	MAPK3	T409	A407T	407	Missense	proximal	-2	no	14.911	16.276	EPSD	ICGC;COSMIC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P29590	PML	P27361	MAPK3	S504	S505F	505	Missense	proximal	1	no	7.286	10.126	EPSD	ICGC	9.358	Gain
CMGC_MAPK_ERK1_MAPK3_ST	P29590	PML	P27361	MAPK3	S505	Q508H	508	Missense	distal	3	no	14.608	14.616	EPSD	ICGC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P29590	PML	P27361	MAPK3	S505	S505F	505	Missense	central	0	yes	14.608	0.000	EPSD	ICGC	9.358	Loss
CMGC_MAPK_ERK1_MAPK3_ST	P29590	PML	P27361	MAPK3	S518	P525L	525	Missense	distal	7	no	16.965	17.158	EPSD	ICGC;COSMIC;GDSC;CCLE	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P29590	PML	P27361	MAPK3	S527	P525L	525	Missense	proximal	-2	no	19.970	18.585	EPSD;PhosphoSitePlus	ICGC;COSMIC;GDSC;CCLE	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P29590	PML	P27361	MAPK3	S527	P526L	526	Missense	proximal	-1	no	19.970	19.875	EPSD;PhosphoSitePlus	ICGC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P29590	PML	P27361	MAPK3	S530	P525L	525	Missense	distal	-5	no	18.937	18.882	EPSD;PhosphoSitePlus	ICGC;COSMIC;GDSC;CCLE	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P29590	PML	P27361	MAPK3	S530	S535L	535	Missense	distal	5	no	18.937	18.666	EPSD;PhosphoSitePlus	ICGC;COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P29590	PML	P27361	MAPK3	S530	P526L	526	Missense	distal	-4	no	18.937	18.824	EPSD;PhosphoSitePlus	ICGC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P29590	PML	P27361	MAPK3	S570	S571F	571	Missense	proximal	1	no	7.206	10.045	EPSD	ICGC	9.358	Gain
CMGC_MAPK_ERK1_MAPK3_ST	P29590	PML	P27361	MAPK3	S583	Q586H	586	Missense	distal	3	no	9.745	9.752	EPSD	ICGC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P29590	PML	P27361	MAPK3	S583	S579I	579	Missense	distal	-4	no	9.745	9.585	EPSD	ICGC;COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P29590	PML	P27361	MAPK3	T592	L593P	593	Missense	proximal	1	no	9.277	18.315	EPSD	ICGC	9.358	Gain
CMGC_MAPK_ERK1_MAPK3_ST	P29590	PML	P27361	MAPK3	S804	V803M	803	Missense	proximal	-1	no	10.169	10.098	EPSD	ICGC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P29590	PML	P27361	MAPK3	T867	R861W	861	Missense	distal	-6	no	17.550	17.028	EPSD	ICGC;COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P29590	PML	P27361	MAPK3	T867	P868T	868	Missense	proximal	1	no	17.550	8.673	EPSD	ICGC	9.358	Loss
CMGC_MAPK_ERK1_MAPK3_ST	P29590	PML	P27361	MAPK3	T867	P868S	868	Missense	proximal	1	no	17.550	8.497	EPSD	ICGC	9.358	Loss
CMGC_MAPK_ERK1_MAPK3_ST	P29590	PML	P27361	MAPK3	T867	G873C	873	Missense	distal	6	no	17.550	16.916	EPSD	ICGC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P29590	PML	P27361	MAPK3	S879	A875T	875	Missense	distal	-4	no	11.285	11.358	EPSD	ICGC;COSMIC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P29590	PML	P27361	MAPK3	S879	G873C	873	Missense	distal	-6	no	11.285	10.788	EPSD	ICGC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P29590	PML	P27361	MAPK3	S879	A875E	875	Missense	distal	-4	no	11.285	11.392	EPSD	ICGC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P29590	PML	P27361	MAPK3	S879	Q880K	880	Missense	proximal	1	no	11.285	2.075	EPSD	ICGC;COSMIC	9.358	Loss
CMGC_MAPK_ERK1_MAPK3_ST	O15027	SEC16A	P27361	MAPK3	S23	P29T	29	Missense	distal	6	no	16.737	16.712	EPSD	ICGC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	O15027	SEC16A	P27361	MAPK3	S23	P29L	29	Missense	distal	6	no	16.737	16.511	EPSD	ICGC;COSMIC;GDSC;CCLE	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	O15027	SEC16A	P27361	MAPK3	S25	P29T	29	Missense	distal	4	no	11.977	11.913	EPSD	ICGC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	O15027	SEC16A	P27361	MAPK3	S25	P29L	29	Missense	distal	4	no	11.977	11.822	EPSD	ICGC;COSMIC;GDSC;CCLE	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	O15027	SEC16A	P27361	MAPK3	S122	P120L	120	Missense	proximal	-2	no	11.074	9.690	EPSD	ICGC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	O15027	SEC16A	P27361	MAPK3	T123	P120L	120	Missense	distal	-3	no	9.400	9.316	EPSD	ICGC	9.358	Loss
CMGC_MAPK_ERK1_MAPK3_ST	O15027	SEC16A	P27361	MAPK3	S164	T169M	169	Missense	distal	5	no	14.950	14.694	EPSD	ICGC;COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	O15027	SEC16A	P27361	MAPK3	S346	S342R	342	Missense	distal	-4	no	10.009	9.932	EPSD	ICGC;COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	O15027	SEC16A	P27361	MAPK3	S779	A777T	777	Missense	proximal	-2	no	14.828	16.193	EPSD	ICGC;COSMIC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	O15027	SEC16A	P27361	MAPK3	S1196	Y1202C	1202	Missense	distal	6	no	9.865	9.380	EPSD	ICGC;COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	O15027	SEC16A	P27361	MAPK3	S1395	P1396Q	1396	Missense	proximal	1	no	15.285	7.341	EPSD	ICGC;COSMIC	9.358	Loss
CMGC_MAPK_ERK1_MAPK3_ST	O15027	SEC16A	P27361	MAPK3	S1663	T1657K	1657	Missense	distal	-6	no	16.551	16.561	EPSD	ICGC;COSMIC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	O15027	SEC16A	P27361	MAPK3	T1810	A1814V	1814	Missense	distal	4	no	13.414	13.522	EPSD	ICGC;COSMIC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	O15027	SEC16A	P27361	MAPK3	T1980	P1976T	1976	Missense	distal	-4	no	9.506	9.475	EPSD	ICGC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q9NRA0	SPHK2	P27361	MAPK3	S477	S473T	473	Missense	distal	-4	no	17.035	16.976	EPSD	ICGC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q9NRA0	SPHK2	P27361	MAPK3	T614	P612Q	612	Missense	proximal	-2	no	17.419	15.655	EPSD;PhosphoSitePlus	ICGC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P05412	JUN	P27361	MAPK3	S63	K70T	70	Missense	distal	7	no	15.849	15.792	EPSD;PhosphoSitePlus	ICGC;COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P05412	JUN	P27361	MAPK3	S73	A72E	72	Missense	proximal	-1	no	16.312	16.421	PhosphoSitePlus;EPSD	ICGC;COSMIC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P05412	JUN	P27361	MAPK3	S73	K70T	70	Missense	distal	-3	no	16.312	16.333	PhosphoSitePlus;EPSD	ICGC;COSMIC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P05412	JUN	P27361	MAPK3	T91	T93N	93	Missense	proximal	2	no	15.046	15.040	EPSD	ICGC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P05412	JUN	P27361	MAPK3	T91	L98R	98	Missense	distal	7	no	15.046	14.946	EPSD	ICGC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P05412	JUN	P27361	MAPK3	T93	T93N	93	Missense	central	0	yes	12.688	0.000	EPSD	ICGC	9.358	Loss
CMGC_MAPK_ERK1_MAPK3_ST	P05412	JUN	P27361	MAPK3	T93	L98R	98	Missense	distal	5	no	12.688	12.815	EPSD	ICGC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P05412	JUN	P27361	MAPK3	T239	T239K	239	Missense	central	0	yes	15.173	0.000	EPSD	ICGC	9.358	Loss
CMGC_MAPK_ERK1_MAPK3_ST	P05412	JUN	P27361	MAPK3	S243	T239K	239	Missense	distal	-4	no	18.294	18.269	EPSD	ICGC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P05412	JUN	P27361	MAPK3	T330	Q327L	327	Missense	distal	-3	no	11.215	11.185	EPSD	ICGC;COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P05412	JUN	P27361	MAPK3	T330	T330K	330	Missense	central	0	yes	11.215	0.000	EPSD	ICGC	9.358	Loss
CMGC_MAPK_ERK1_MAPK3_ST	P05412	JUN	P27361	MAPK3	T330	M323I	323	Missense	distal	-7	no	11.215	11.202	EPSD	ICGC;COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q03060	CREM	P27361	MAPK3	S24	Q25K	25	Missense	proximal	1	no	11.372	2.163	EPSD	ICGC;COSMIC	9.358	Loss
CMGC_MAPK_ERK1_MAPK3_ST	Q02750	MAP2K1	P27361	MAPK3	S24	G17V	17	Missense	distal	-7	no	9.481	9.593	EPSD	ICGC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q02750	MAP2K1	P27361	MAPK3	S222	L215I	215	Missense	distal	-7	no	9.353	9.399	EPSD	ICGC;COSMIC	9.358	Gain
CMGC_MAPK_ERK1_MAPK3_ST	Q02750	MAP2K1	P27361	MAPK3	S231	P232R	232	Missense	proximal	1	no	17.940	8.439	EPSD	ICGC	9.358	Loss
CMGC_MAPK_ERK1_MAPK3_ST	Q02750	MAP2K1	P27361	MAPK3	S231	R234I	234	Missense	distal	3	no	17.940	17.911	EPSD	ICGC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q02750	MAP2K1	P27361	MAPK3	S231	G225C	225	Missense	distal	-6	no	17.940	17.443	EPSD	ICGC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q02750	MAP2K1	P27361	MAPK3	T286	P288H	288	Missense	proximal	2	no	14.936	14.923	PhosphoSitePlus;EPSD	ICGC;COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q02750	MAP2K1	P27361	MAPK3	T292	P288H	288	Missense	distal	-4	no	16.441	16.406	EPSD;PhosphoSitePlus	ICGC;COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q02750	MAP2K1	P27361	MAPK3	T292	G294W	294	Missense	proximal	2	no	16.441	16.385	EPSD;PhosphoSitePlus	ICGC;COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q02750	MAP2K1	P27361	MAPK3	T292	P296H	296	Missense	distal	4	no	16.441	16.349	EPSD;PhosphoSitePlus	ICGC;COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q02750	MAP2K1	P27361	MAPK3	S299	G294W	294	Missense	distal	-5	no	9.721	9.565	EPSD	ICGC;COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q02750	MAP2K1	P27361	MAPK3	S299	P296H	296	Missense	distal	-3	no	9.721	9.681	EPSD	ICGC;COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q02750	MAP2K1	P27361	MAPK3	S385	S385G	385	Missense	central	0	yes	9.803	0.000	EPSD	ICGC	9.358	Loss
CMGC_MAPK_ERK1_MAPK3_ST	Q02750	MAP2K1	P27361	MAPK3	T386	S385G	385	Missense	proximal	-1	no	20.053	19.987	EPSD	ICGC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q02750	MAP2K1	P27361	MAPK3	T388	S385G	385	Missense	distal	-3	no	10.530	10.497	EPSD	ICGC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q00613	HSF1	P27361	MAPK3	S244	P239L	239	Missense	distal	-5	no	15.761	15.706	EPSD	ICGC;CCLE	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q00613	HSF1	P27361	MAPK3	S275	A278T	278	Missense	distal	3	no	17.431	17.461	EPSD	ICGC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q00613	HSF1	P27361	MAPK3	S279	A278T	278	Missense	proximal	-1	no	14.389	14.493	EPSD	ICGC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q00613	HSF1	P27361	MAPK3	S419	S421L	421	Missense	proximal	2	no	15.478	15.454	EPSD	ICGC;COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q00613	HSF1	P27361	MAPK3	S419	S419G	419	Missense	central	0	yes	15.478	0.000	EPSD	ICGC;COSMIC	9.358	Loss
CMGC_MAPK_ERK1_MAPK3_ST	Q00613	HSF1	P27361	MAPK3	S444	A437S	437	Missense	distal	-7	no	18.515	18.365	EPSD	ICGC;COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q00613	HSF1	P27361	MAPK3	S518	A523V	523	Missense	distal	5	no	10.477	10.465	EPSD	ICGC;COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q9UIG0	BAZ1B	P27361	MAPK3	S158	G154C	154	Missense	distal	-4	no	15.160	14.960	PhosphoSitePlus	ICGC;COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q9UIG0	BAZ1B	P27361	MAPK3	S158	S161N	161	Missense	distal	3	no	15.160	15.139	PhosphoSitePlus	ICGC;COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q9UIG0	BAZ1B	P27361	MAPK3	S158	N165K	165	Missense	distal	7	no	15.160	15.169	PhosphoSitePlus	ICGC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q9UIG0	BAZ1B	P27361	MAPK3	S161	G154C	154	Missense	distal	-7	no	10.489	10.721	EPSD	ICGC;COSMIC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q9UIG0	BAZ1B	P27361	MAPK3	S161	S161N	161	Missense	central	0	yes	10.489	0.000	EPSD	ICGC;COSMIC	9.358	Loss
CMGC_MAPK_ERK1_MAPK3_ST	Q9UIG0	BAZ1B	P27361	MAPK3	S161	N165K	165	Missense	distal	4	no	10.489	10.497	EPSD	ICGC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q9UIG0	BAZ1B	P27361	MAPK3	S197	R193S	193	Missense	distal	-4	no	17.898	17.975	EPSD	ICGC;COSMIC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q9UIG0	BAZ1B	P27361	MAPK3	S197	R196T	196	Missense	proximal	-1	no	17.898	17.909	EPSD	ICGC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q9UIG0	BAZ1B	P27361	MAPK3	S312	D314E	314	Missense	proximal	2	no	17.440	17.443	EPSD	ICGC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q9UIG0	BAZ1B	P27361	MAPK3	S312	P317T	317	Missense	distal	5	no	17.440	17.347	EPSD	ICGC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q9UIG0	BAZ1B	P27361	MAPK3	S312	K319N	319	Missense	distal	7	no	17.440	17.431	EPSD	ICGC;COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q9UIG0	BAZ1B	P27361	MAPK3	S349	S349L	349	Missense	central	0	yes	14.444	0.000	EPSD	ICGC;COSMIC	9.358	Loss
CMGC_MAPK_ERK1_MAPK3_ST	Q9UIG0	BAZ1B	P27361	MAPK3	S423	P424S	424	Missense	proximal	1	no	16.421	7.367	EPSD	ICGC;COSMIC	9.358	Loss
CMGC_MAPK_ERK1_MAPK3_ST	Q9UIG0	BAZ1B	P27361	MAPK3	S423	G419W	419	Missense	distal	-4	no	16.421	16.175	EPSD	ICGC;COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q9UIG0	BAZ1B	P27361	MAPK3	T430	P424S	424	Missense	distal	-6	no	15.578	15.662	EPSD	ICGC;COSMIC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q9UIG0	BAZ1B	P27361	MAPK3	T983	T982N	982	Missense	proximal	-1	no	15.432	15.414	EPSD	ICGC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q9UIG0	BAZ1B	P27361	MAPK3	T983	A978S	978	Missense	distal	-5	no	15.432	15.531	EPSD	ICGC;COSMIC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q9UIG0	BAZ1B	P27361	MAPK3	S1468	P1470S	1470	Missense	proximal	2	no	9.795	9.797	EPSD	ICGC;COSMIC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q9UIG0	BAZ1B	P27361	MAPK3	S1468	P1470Q	1470	Missense	proximal	2	no	9.795	9.775	EPSD	ICGC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q9UIG0	BAZ1B	P27361	MAPK3	S1468	P1470L	1470	Missense	proximal	2	no	9.795	9.773	EPSD	ICGC;COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q9UIG0	BAZ1B	P27361	MAPK3	S1476	P1470S	1470	Missense	distal	-6	no	9.496	9.581	EPSD	ICGC;COSMIC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q9UIG0	BAZ1B	P27361	MAPK3	S1476	P1470Q	1470	Missense	distal	-6	no	9.496	9.430	EPSD	ICGC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q9UIG0	BAZ1B	P27361	MAPK3	S1476	P1470L	1470	Missense	distal	-6	no	9.496	9.249	EPSD	ICGC;COSMIC	9.358	Loss
CMGC_MAPK_ERK1_MAPK3_ST	Q9ULV5	HSF4	P27361	MAPK3	S40	S45C	45	Missense	distal	5	no	13.622	13.099	EPSD	ICGC;COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q9ULV5	HSF4	P27361	MAPK3	S40	L36P	36	Missense	distal	-4	no	13.622	13.735	EPSD	ICGC;COSMIC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q9ULV5	HSF4	P27361	MAPK3	S298	G301V	301	Missense	distal	3	no	17.561	17.539	PhosphoSitePlus	ICGC;COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q9ULV5	HSF4	P27361	MAPK3	S489	G485V	485	Missense	distal	-4	no	18.414	18.300	EPSD	ICGC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q9ULV5	HSF4	P27361	MAPK3	S491	G485V	485	Missense	distal	-6	no	19.828	19.561	EPSD	ICGC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q8N122	RPTOR	P27361	MAPK3	S8	M5I	5	Missense	distal	-3	no	16.132	16.148	EPSD;PhosphoSitePlus	ICGC;COSMIC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q8N122	RPTOR	P27361	MAPK3	S8	G12V	12	Missense	distal	4	no	16.132	16.069	EPSD;PhosphoSitePlus	ICGC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q8N122	RPTOR	P27361	MAPK3	S8	G14R	14	Missense	distal	6	no	16.132	16.122	EPSD;PhosphoSitePlus	ICGC;COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q8N122	RPTOR	P27361	MAPK3	S696	T699M	699	Missense	distal	3	no	16.759	16.711	PhosphoSitePlus;EPSD	ICGC;COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q8N122	RPTOR	P27361	MAPK3	T706	T699M	699	Missense	distal	-7	no	16.131	16.260	EPSD	ICGC;COSMIC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q8N122	RPTOR	P27361	MAPK3	S881	S887N	887	Missense	distal	6	no	9.382	9.153	EPSD	ICGC;COSMIC	9.358	Loss
CMGC_MAPK_ERK1_MAPK3_ST	Q8N122	RPTOR	P27361	MAPK3	T917	A914V	914	Missense	distal	-3	no	14.001	14.020	EPSD	ICGC;COSMIC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q8N122	RPTOR	P27361	MAPK3	S920	A914V	914	Missense	distal	-6	no	10.601	10.588	EPSD	ICGC;COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P49407	ARRB1	P27361	MAPK3	S86	V84I	84	Missense	proximal	-2	no	10.307	10.122	EPSD	ICGC;COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P49407	ARRB1	P27361	MAPK3	S86	N83K	83	Missense	distal	-3	no	10.307	10.300	EPSD	ICGC;COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P49407	ARRB1	P27361	MAPK3	S86	P88Q	88	Missense	proximal	2	no	10.307	10.287	EPSD	ICGC;COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P49407	ARRB1	P27361	MAPK3	S86	L79M	79	Missense	distal	-7	no	10.307	10.367	EPSD	ICGC;COSMIC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P49407	ARRB1	P27361	MAPK3	T275	Y272C	272	Missense	distal	-3	no	14.733	14.618	EPSD	ICGC;COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P49407	ARRB1	P27361	MAPK3	T275	A279D	279	Missense	distal	4	no	14.733	14.944	EPSD	ICGC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P49407	ARRB1	P27361	MAPK3	T275	P276L	276	Missense	proximal	1	no	14.733	5.695	EPSD	ICGC	9.358	Loss
CMGC_MAPK_ERK1_MAPK3_ST	P49407	ARRB1	P27361	MAPK3	S412	Q414H	414	Missense	proximal	2	no	19.354	19.361	PhosphoSitePlus	ICGC;COSMIC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P27361	MAPK3	P27361	MAPK3	S263	N270I	270	Missense	distal	7	no	18.959	19.192	EPSD	ICGC;COSMIC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P31645	SLC6A4	P27361	MAPK3	S52	S52R	52	Missense	central	0	yes	17.221	0.000	EPSD	ICGC;COSMIC	9.358	Loss
CMGC_MAPK_ERK1_MAPK3_ST	P31645	SLC6A4	P27361	MAPK3	S559	S559R	559	Missense	central	0	yes	17.046	0.000	EPSD	ICGC	9.358	Loss
CMGC_MAPK_ERK1_MAPK3_ST	P31645	SLC6A4	P27361	MAPK3	S559	P561L	561	Missense	proximal	2	no	17.046	17.024	EPSD	ICGC;COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P31645	SLC6A4	P27361	MAPK3	S559	S555I	555	Missense	distal	-4	no	17.046	16.887	EPSD	ICGC;GDSC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P31645	SLC6A4	P27361	MAPK3	S559	P561S	561	Missense	proximal	2	no	17.046	17.048	EPSD	ICGC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P31645	SLC6A4	P27361	MAPK3	T603	K605N	605	Missense	proximal	2	no	10.235	10.234	EPSD	ICGC;COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P31645	SLC6A4	P27361	MAPK3	T603	G602E	602	Missense	proximal	-1	no	10.235	10.276	EPSD	ICGC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P31645	SLC6A4	P27361	MAPK3	T613	P617Q	617	Missense	distal	4	no	18.182	18.040	EPSD	ICGC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P31645	SLC6A4	P27361	MAPK3	T616	P617Q	617	Missense	proximal	1	no	19.810	11.866	PhosphoSitePlus	ICGC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P33076	CIITA	P27361	MAPK3	T740	P741S	741	Missense	proximal	1	no	17.067	8.013	EPSD	ICGC;COSMIC	9.358	Loss
CMGC_MAPK_ERK1_MAPK3_ST	P33076	CIITA	P27361	MAPK3	T740	A738T	738	Missense	proximal	-2	no	17.067	18.432	EPSD	ICGC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P78347	GTF2I	P27361	MAPK3	S19	S17L	17	Missense	proximal	-2	no	9.384	9.075	EPSD	ICGC;COSMIC	9.358	Loss
CMGC_MAPK_ERK1_MAPK3_ST	P78347	GTF2I	P27361	MAPK3	T24	S17L	17	Missense	distal	-7	no	12.054	12.199	EPSD	ICGC;COSMIC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P78347	GTF2I	P27361	MAPK3	S210	A204T	204	Missense	distal	-6	no	15.908	16.056	EPSD	ICGC;COSMIC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P78347	GTF2I	P27361	MAPK3	S210	C215S	215	Missense	distal	5	no	15.908	16.431	EPSD	ICGC;COSMIC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P78347	GTF2I	P27361	MAPK3	S210	A204S	204	Missense	distal	-6	no	15.908	16.224	EPSD	ICGC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q14790	CASP8	P27361	MAPK3	S21	L22F	22	Missense	proximal	1	no	9.018	11.842	EPSD	ICGC;COSMIC	9.358	Gain
CMGC_MAPK_ERK1_MAPK3_ST	Q14790	CASP8	P27361	MAPK3	S26	F24L	24	Missense	proximal	-2	no	8.386	9.378	EPSD	ICGC;COSMIC	9.358	Gain
CMGC_MAPK_ERK1_MAPK3_ST	Q14790	CASP8	P27361	MAPK3	S60	L62P	62	Missense	proximal	2	no	9.486	9.508	EPSD	ICGC;COSMIC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q14790	CASP8	P27361	MAPK3	S60	S57C	57	Missense	distal	-3	no	9.486	9.308	EPSD	ICGC;COSMIC	9.358	Loss
CMGC_MAPK_ERK1_MAPK3_ST	Q14790	CASP8	P27361	MAPK3	S60	F67L	67	Missense	distal	7	no	9.486	9.265	EPSD	ICGC;COSMIC	9.358	Loss
CMGC_MAPK_ERK1_MAPK3_ST	Q14790	CASP8	P27361	MAPK3	S60	N58S	58	Missense	proximal	-2	no	9.486	10.431	EPSD	ICGC;COSMIC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q14790	CASP8	P27361	MAPK3	S60	S60P	60	Missense	central	0	yes	9.486	0.000	EPSD	ICGC;COSMIC	9.358	Loss
CMGC_MAPK_ERK1_MAPK3_ST	Q14790	CASP8	P27361	MAPK3	S60	E64V	64	Missense	distal	4	no	9.486	9.363	EPSD	ICGC;COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q9BR01	SULT4A1	P27361	MAPK3	T8	T11I	11	Missense	distal	3	no	15.149	15.111	EPSD	ICGC;COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q9BR01	SULT4A1	P27361	MAPK3	T8	P9S	9	Missense	proximal	1	no	15.149	6.096	EPSD	ICGC;COSMIC	9.358	Loss
CMGC_MAPK_ERK1_MAPK3_ST	Q9BR01	SULT4A1	P27361	MAPK3	T8	A2V	2	Missense	distal	-6	no	15.149	15.136	EPSD	ICGC;COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q9BR01	SULT4A1	P27361	MAPK3	T11	T11I	11	Missense	central	0	yes	17.810	0.000	PhosphoSitePlus	ICGC;COSMIC	9.358	Loss
CMGC_MAPK_ERK1_MAPK3_ST	Q9BR01	SULT4A1	P27361	MAPK3	T11	P9S	9	Missense	proximal	-2	no	17.810	16.734	PhosphoSitePlus	ICGC;COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	O43521	BCL2L11	P27361	MAPK3	S59	G62S	62	Missense	distal	3	no	16.761	16.776	EPSD	ICGC;COSMIC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	O43521	BCL2L11	P27361	MAPK3	S59	P56L	56	Missense	distal	-3	no	16.761	16.676	EPSD	ICGC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	O43521	BCL2L11	P27361	MAPK3	S59	G52W	52	Missense	distal	-7	no	16.761	17.052	EPSD	ICGC;COSMIC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	O43521	BCL2L11	P27361	MAPK3	S69	G62S	62	Missense	distal	-7	no	18.489	18.452	PhosphoSitePlus	ICGC;COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	O43521	BCL2L11	P27361	MAPK3	S77	R84G	84	Missense	distal	7	no	15.478	15.447	EPSD	ICGC;COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	O43521	BCL2L11	P27361	MAPK3	S98	G95W	95	Missense	distal	-3	no	10.615	10.442	EPSD	ICGC;COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	O43521	BCL2L11	P27361	MAPK3	S98	S92Y	92	Missense	distal	-6	no	10.615	10.362	EPSD	ICGC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	O43521	BCL2L11	P27361	MAPK3	T116	K112T	112	Missense	distal	-4	no	16.362	16.388	EPSD	ICGC;COSMIC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	O43521	BCL2L11	P27361	MAPK3	T116	A123T	123	Missense	distal	7	no	16.362	16.134	EPSD	ICGC;COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	O43521	BCL2L11	P27361	MAPK3	S118	K112T	112	Missense	distal	-6	no	17.819	17.809	EPSD	ICGC;COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	O43521	BCL2L11	P27361	MAPK3	S118	A123T	123	Missense	distal	5	no	17.819	17.939	EPSD	ICGC;COSMIC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q9ULC4	MCTS1	P27361	MAPK3	S118	I111M	111	Missense	distal	-7	no	14.525	14.538	EPSD	ICGC;COSMIC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q9ULC4	MCTS1	P27361	MAPK3	S118	P114L	114	Missense	distal	-4	no	14.525	14.412	EPSD	ICGC;COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q9ULC4	MCTS1	P27361	MAPK3	S118	P125L	125	Missense	distal	7	no	14.525	14.717	EPSD	ICGC;COSMIC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P42229	STAT5A	P27361	MAPK3	S128	P129T	129	Missense	proximal	1	no	12.917	4.040	EPSD	ICGC;COSMIC	9.358	Loss
CMGC_MAPK_ERK1_MAPK3_ST	P42229	STAT5A	P27361	MAPK3	S777	D773Y	773	Missense	distal	-4	no	9.885	9.818	EPSD	ICGC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P42229	STAT5A	P27361	MAPK3	S780	D773Y	773	Missense	distal	-7	no	18.628	18.703	PhosphoSitePlus	ICGC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q15366	PCBP2	P27361	MAPK3	S90	R95T	95	Missense	distal	5	no	9.558	9.566	EPSD	ICGC;COSMIC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q15366	PCBP2	P27361	MAPK3	S107	G114E	114	Missense	distal	7	no	10.101	10.066	EPSD	ICGC;COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q15366	PCBP2	P27361	MAPK3	S107	L100R	100	Missense	distal	-7	no	10.101	10.039	EPSD	ICGC;COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q15366	PCBP2	P27361	MAPK3	S107	C109Y	109	Missense	proximal	2	no	10.101	10.141	EPSD	ICGC;COSMIC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q15366	PCBP2	P27361	MAPK3	S188	A194S	194	Missense	distal	6	no	9.654	10.180	EPSD	ICGC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q15366	PCBP2	P27361	MAPK3	S189	A194S	194	Missense	distal	5	no	16.547	16.802	EPSD;PhosphoSitePlus	ICGC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q15366	PCBP2	P27361	MAPK3	T213	L218H	218	Missense	distal	5	no	14.340	14.503	EPSD;PhosphoSitePlus	ICGC;COSMIC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q8N9N5	BANP	P27361	MAPK3	S19	D17H	17	Missense	proximal	-2	no	19.122	19.501	EPSD	ICGC;COSMIC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q16559	TAL2	P27361	MAPK3	S100	H105Y	105	Missense	distal	5	no	19.528	19.420	PhosphoSitePlus	ICGC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q16559	TAL2	P27361	MAPK3	S100	P103S	103	Missense	distal	3	no	19.528	19.523	PhosphoSitePlus	ICGC;COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	O00429	DNM1L	P27361	MAPK3	S126	K123N	123	Missense	distal	-3	no	16.284	16.291	EPSD	ICGC;COSMIC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	O00429	DNM1L	P27361	MAPK3	S544	A539S	539	Missense	distal	-5	no	9.422	9.521	EPSD	ICGC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	O00429	DNM1L	P27361	MAPK3	S544	A541S	541	Missense	distal	-3	no	9.422	9.514	EPSD	ICGC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	O00429	DNM1L	P27361	MAPK3	S544	S548F	548	Missense	distal	4	no	9.422	9.008	EPSD	ICGC;COSMIC	9.358	Loss
CMGC_MAPK_ERK1_MAPK3_ST	O00429	DNM1L	P27361	MAPK3	S544	S548Y	548	Missense	distal	4	no	9.422	9.206	EPSD	ICGC;COSMIC	9.358	Loss
CMGC_MAPK_ERK1_MAPK3_ST	O00429	DNM1L	P27361	MAPK3	S548	A541S	541	Missense	distal	-7	no	16.860	16.710	EPSD	ICGC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	O00429	DNM1L	P27361	MAPK3	S548	S548F	548	Missense	central	0	yes	16.860	0.000	EPSD	ICGC;COSMIC	9.358	Loss
CMGC_MAPK_ERK1_MAPK3_ST	O00429	DNM1L	P27361	MAPK3	S548	A553T	553	Missense	distal	5	no	16.860	16.980	EPSD	ICGC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	O00429	DNM1L	P27361	MAPK3	S548	A553V	553	Missense	distal	5	no	16.860	16.849	EPSD	ICGC;COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	O00429	DNM1L	P27361	MAPK3	S548	S548Y	548	Missense	central	0	yes	16.860	0.000	EPSD	ICGC;COSMIC	9.358	Loss
CMGC_MAPK_ERK1_MAPK3_ST	P17542	TAL1	P27361	MAPK3	S122	A125T	125	Missense	distal	3	no	16.727	16.758	PhosphoSitePlus	ICGC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P17542	TAL1	P27361	MAPK3	S172	P173L	173	Missense	proximal	1	no	14.841	5.803	EPSD	ICGC	9.358	Loss
CMGC_MAPK_ERK1_MAPK3_ST	P17542	TAL1	P27361	MAPK3	S303	P310H	310	Missense	distal	7	no	11.936	11.996	EPSD	ICGC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P17542	TAL1	P27361	MAPK3	S303	P310T	310	Missense	distal	7	no	11.936	11.977	EPSD	ICGC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P17542	TAL1	P27361	MAPK3	S303	P308L	308	Missense	distal	5	no	11.936	11.709	EPSD	ICGC;COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P17542	TAL1	P27361	MAPK3	T313	P310H	310	Missense	distal	-3	no	9.647	9.607	EPSD	ICGC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P17542	TAL1	P27361	MAPK3	T313	P310T	310	Missense	distal	-3	no	9.647	9.608	EPSD	ICGC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P17542	TAL1	P27361	MAPK3	T313	P308L	308	Missense	distal	-5	no	9.647	9.592	EPSD	ICGC;COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P17542	TAL1	P27361	MAPK3	S316	P310H	310	Missense	distal	-6	no	9.898	9.818	EPSD	ICGC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P17542	TAL1	P27361	MAPK3	S316	P310T	310	Missense	distal	-6	no	9.898	9.814	EPSD	ICGC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q13485	SMAD4	P27361	MAPK3	T9	S5C	5	Missense	distal	-4	no	14.802	14.564	EPSD	ICGC;COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q13485	SMAD4	P27361	MAPK3	T9	M4L	4	Missense	distal	-5	no	14.802	14.861	EPSD	ICGC;COSMIC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q13485	SMAD4	P27361	MAPK3	T9	T11K	11	Missense	proximal	2	no	14.802	14.797	EPSD	ICGC;COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q13485	SMAD4	P27361	MAPK3	S42	L43F	43	Missense	proximal	1	no	8.265	11.089	EPSD	ICGC;COSMIC	9.358	Gain
CMGC_MAPK_ERK1_MAPK3_ST	Q13485	SMAD4	P27361	MAPK3	S138	Y131S	131	Missense	distal	-7	no	15.185	15.066	EPSD	ICGC;COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q13485	SMAD4	P27361	MAPK3	S138	H132D	132	Missense	distal	-6	no	15.185	15.289	EPSD	ICGC;COSMIC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q13485	SMAD4	P27361	MAPK3	S138	V136A	136	Missense	proximal	-2	no	15.185	14.488	EPSD	ICGC;COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q13485	SMAD4	P27361	MAPK3	S138	R135L	135	Missense	distal	-3	no	15.185	15.147	EPSD	ICGC;COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q13485	SMAD4	P27361	MAPK3	S138	V137L	137	Missense	proximal	-1	no	15.185	15.180	EPSD	ICGC;COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q13485	SMAD4	P27361	MAPK3	S138	Y131C	131	Missense	distal	-7	no	15.185	15.336	EPSD	ICGC;COSMIC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q13485	SMAD4	P27361	MAPK3	S171	L172F	172	Missense	proximal	1	no	7.269	10.093	EPSD	ICGC	9.358	Gain
CMGC_MAPK_ERK1_MAPK3_ST	Q13485	SMAD4	P27361	MAPK3	S504	C499R	499	Missense	distal	-5	no	9.251	9.368	EPSD	ICGC;COSMIC	9.358	Gain
CMGC_MAPK_ERK1_MAPK3_ST	P00533	EGFR	P27361	MAPK3	S77	I82F	82	Missense	distal	5	no	10.908	10.877	EPSD	ICGC;COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P00533	EGFR	P27361	MAPK3	S511	V505L	505	Missense	distal	-6	no	15.023	15.021	EPSD	ICGC;COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P00533	EGFR	P27361	MAPK3	S511	C510R	510	Missense	proximal	-1	no	15.023	15.208	EPSD	ICGC;COSMIC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P00533	EGFR	P27361	MAPK3	T693	A698T	698	Missense	distal	5	no	18.879	18.998	PhosphoSitePlus	ICGC;COSMIC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P00533	EGFR	P27361	MAPK3	S991	R986Q	986	Missense	distal	-5	no	16.779	16.771	EPSD	ICGC;COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P00533	EGFR	P27361	MAPK3	S991	S991R	991	Missense	central	0	yes	16.779	0.000	EPSD	ICGC;COSMIC	9.358	Loss
CMGC_MAPK_ERK1_MAPK3_ST	P00533	EGFR	P27361	MAPK3	S991	L989I	989	Missense	proximal	-2	no	16.779	16.325	EPSD	ICGC;COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P00533	EGFR	P27361	MAPK3	S1153	A1155T	1155	Missense	proximal	2	no	15.338	15.365	EPSD	ICGC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P00533	EGFR	P27361	MAPK3	S1153	H1156N	1156	Missense	distal	3	no	15.338	15.331	EPSD	ICGC;COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P00533	EGFR	P27361	MAPK3	S1153	S1153I	1153	Missense	central	0	yes	15.338	0.000	EPSD	ICGC;COSMIC	9.358	Loss
CMGC_MAPK_ERK1_MAPK3_ST	P00533	EGFR	P27361	MAPK3	S1153	F1151I	1151	Missense	proximal	-2	no	15.338	15.875	EPSD	ICGC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P00533	EGFR	P27361	MAPK3	S1153	S1153N	1153	Missense	central	0	yes	15.338	0.000	EPSD	ICGC;COSMIC	9.358	Loss
CMGC_MAPK_ERK1_MAPK3_ST	P00533	EGFR	P27361	MAPK3	S1204	Y1197C	1197	Missense	distal	-7	no	11.806	11.957	EPSD	ICGC;COSMIC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P00533	EGFR	P27361	MAPK3	S1204	L1198I	1198	Missense	distal	-6	no	11.806	11.739	EPSD	ICGC;COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P00533	EGFR	P27361	MAPK3	S1205	L1198I	1198	Missense	distal	-7	no	10.816	10.863	EPSD	ICGC;COSMIC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P63000	RAC1	P27361	MAPK3	S71	Y72C	72	Missense	proximal	1	no	11.073	2.813	EPSD	ICGC;COSMIC	9.358	Loss
CMGC_MAPK_ERK1_MAPK3_ST	P63000	RAC1	P27361	MAPK3	S89	N92K	92	Missense	distal	3	no	12.292	12.289	EPSD	ICGC;COSMIC;CCLE	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P63000	RAC1	P27361	MAPK3	S89	S83P	83	Missense	distal	-6	no	12.292	12.207	EPSD	ICGC;COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P63000	RAC1	P27361	MAPK3	S89	N92T	92	Missense	distal	3	no	12.292	12.299	EPSD	ICGC;CCLE	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P63000	RAC1	P27361	MAPK3	S89	P87L	87	Missense	proximal	-2	no	12.292	10.908	EPSD	ICGC;COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	O60244	MED14	P27361	MAPK3	S151	R148H	148	Missense	distal	-3	no	10.021	10.027	EPSD	ICGC;COSMIC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	O60244	MED14	P27361	MAPK3	S151	R148S	148	Missense	distal	-3	no	10.021	10.059	EPSD	ICGC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	O60244	MED14	P27361	MAPK3	S986	P984L	984	Missense	proximal	-2	no	17.048	15.664	PhosphoSitePlus	ICGC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	O60244	MED14	P27361	MAPK3	S1061	S1064L	1064	Missense	distal	3	no	13.717	13.685	EPSD	ICGC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	O60244	MED14	P27361	MAPK3	S1061	T1068A	1068	Missense	distal	7	no	13.717	13.944	EPSD	ICGC;COSMIC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	O60244	MED14	P27361	MAPK3	S1064	S1064L	1064	Missense	central	0	yes	11.437	0.000	EPSD	ICGC	9.358	Loss
CMGC_MAPK_ERK1_MAPK3_ST	O60244	MED14	P27361	MAPK3	S1064	T1068A	1068	Missense	distal	4	no	11.437	11.218	EPSD	ICGC;COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	O60244	MED14	P27361	MAPK3	S1086	G1081W	1081	Missense	distal	-5	no	15.169	15.013	EPSD	ICGC;COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	O60244	MED14	P27361	MAPK3	S1119	A1121S	1121	Missense	proximal	2	no	14.917	14.956	EPSD	ICGC;COSMIC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	O60244	MED14	P27361	MAPK3	S1128	M1127K	1127	Missense	proximal	-1	no	16.417	16.517	EPSD	ICGC;COSMIC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	O60244	MED14	P27361	MAPK3	S1128	A1121S	1121	Missense	distal	-7	no	16.417	16.267	EPSD	ICGC;COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	O60244	MED14	P27361	MAPK3	S1144	P1145H	1145	Missense	proximal	1	no	16.725	8.969	EPSD	ICGC;COSMIC	9.358	Loss
CMGC_MAPK_ERK1_MAPK3_ST	O60244	MED14	P27361	MAPK3	S1151	N1157K	1157	Missense	distal	6	no	9.953	9.974	EPSD	ICGC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	O60244	MED14	P27361	MAPK3	S1151	P1145H	1145	Missense	distal	-6	no	9.953	9.873	EPSD	ICGC;COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	O60244	MED14	P27361	MAPK3	S1254	T1257N	1257	Missense	distal	3	no	15.993	15.986	EPSD	ICGC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	O60244	MED14	P27361	MAPK3	S1254	P1255H	1255	Missense	proximal	1	no	15.993	8.238	EPSD	ICGC;COSMIC	9.358	Loss
CMGC_MAPK_ERK1_MAPK3_ST	O60244	MED14	P27361	MAPK3	T1354	P1347Q	1347	Missense	distal	-7	no	17.503	17.548	EPSD	ICGC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P61978	HNRNPK	P27361	MAPK3	S116	T118N	118	Missense	proximal	2	no	16.938	16.932	EPSD	ICGC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P61978	HNRNPK	P27361	MAPK3	S116	E110Q	110	Missense	distal	-6	no	16.938	16.804	EPSD	ICGC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P61978	HNRNPK	P27361	MAPK3	S116	E110D	110	Missense	distal	-6	no	16.938	16.894	EPSD	ICGC;COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P61978	HNRNPK	P27361	MAPK3	S116	L123H	123	Missense	distal	7	no	16.938	16.805	EPSD	ICGC;COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P61978	HNRNPK	P27361	MAPK3	S216	D211H	211	Missense	distal	-5	no	14.264	14.262	EPSD	ICGC;COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P61978	HNRNPK	P27361	MAPK3	S216	I213M	213	Missense	distal	-3	no	14.264	14.248	EPSD	ICGC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P61978	HNRNPK	P27361	MAPK3	S379	G384D	384	Missense	distal	5	no	10.614	10.637	EPSD	ICGC;COSMIC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P61978	HNRNPK	P27361	MAPK3	S379	G385V	385	Missense	distal	6	no	10.614	10.408	EPSD	ICGC;COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P61978	HNRNPK	P27361	MAPK3	S379	R377S	377	Missense	proximal	-2	no	10.614	10.938	EPSD	ICGC;COSMIC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P61978	HNRNPK	P27361	MAPK3	S379	A374E	374	Missense	distal	-5	no	10.614	10.679	EPSD	ICGC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P61978	HNRNPK	P27361	MAPK3	S379	G385R	385	Missense	distal	6	no	10.614	10.605	EPSD	ICGC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P61978	HNRNPK	P27361	MAPK3	S454	G460A	460	Missense	distal	6	no	9.804	9.510	EPSD	ICGC;COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P61978	HNRNPK	P27361	MAPK3	S454	Y458H	458	Missense	distal	4	no	9.804	9.879	EPSD	ICGC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P29966	MARCKS	P27361	MAPK3	S27	G20V	20	Missense	distal	-7	no	17.186	17.298	EPSD	ICGC;COSMIC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P29966	MARCKS	P27361	MAPK3	S27	G33R	33	Missense	distal	6	no	17.186	17.177	EPSD	ICGC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P29966	MARCKS	P27361	MAPK3	S81	E86K	86	Missense	distal	5	no	14.722	14.594	EPSD	ICGC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P29966	MARCKS	P27361	MAPK3	S118	S118L	118	Missense	central	0	yes	17.485	0.000	EPSD	ICGC;COSMIC	9.358	Loss
CMGC_MAPK_ERK1_MAPK3_ST	P29966	MARCKS	P27361	MAPK3	S118	E125G	125	Missense	distal	7	no	17.485	17.520	EPSD	ICGC;COSMIC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P29966	MARCKS	P27361	MAPK3	S135	S132L	132	Missense	distal	-3	no	17.009	16.933	EPSD	ICGC;COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P29966	MARCKS	P27361	MAPK3	S135	S134T	134	Missense	proximal	-1	no	17.009	16.979	EPSD	ICGC;COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P29966	MARCKS	P27361	MAPK3	T143	P144S	144	Missense	proximal	1	no	13.202	4.149	EPSD	ICGC;COSMIC	9.358	Loss
CMGC_MAPK_ERK1_MAPK3_ST	P29966	MARCKS	P27361	MAPK3	S145	P144S	144	Missense	proximal	-1	no	16.801	16.795	EPSD	ICGC;COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P29966	MARCKS	P27361	MAPK3	T150	P144S	144	Missense	distal	-6	no	15.194	15.278	EPSD	ICGC;COSMIC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P29966	MARCKS	P27361	MAPK3	S314	S314L	314	Missense	central	0	yes	11.578	0.000	EPSD	ICGC;COSMIC	9.358	Loss
CMGC_MAPK_ERK1_MAPK3_ST	O43524	FOXO3	P27361	MAPK3	S7	P10T	10	Missense	distal	3	no	16.050	16.031	EPSD	ICGC;COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	O43524	FOXO3	P27361	MAPK3	S12	P10T	10	Missense	proximal	-2	no	18.980	17.994	EPSD;PhosphoSitePlus	ICGC;COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	O43524	FOXO3	P27361	MAPK3	S26	S26C	26	Missense	central	0	yes	11.724	0.000	EPSD	ICGC;COSMIC	9.358	Loss
CMGC_MAPK_ERK1_MAPK3_ST	O43524	FOXO3	P27361	MAPK3	S161	T167I	167	Missense	distal	6	no	10.249	9.834	EPSD	ICGC;COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	O43524	FOXO3	P27361	MAPK3	S161	T167A	167	Missense	distal	6	no	10.249	9.878	EPSD	ICGC;COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	O43524	FOXO3	P27361	MAPK3	S161	R168S	168	Missense	distal	7	no	10.249	10.079	EPSD	ICGC;COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	O43524	FOXO3	P27361	MAPK3	S161	R168H	168	Missense	distal	7	no	10.249	10.216	EPSD	ICGC;COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	O43524	FOXO3	P27361	MAPK3	S284	S286T	286	Missense	proximal	2	no	17.661	17.650	EPSD	ICGC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	O43524	FOXO3	P27361	MAPK3	S284	S286F	286	Missense	proximal	2	no	17.661	17.611	EPSD	ICGC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	O43524	FOXO3	P27361	MAPK3	S325	S330N	330	Missense	distal	5	no	15.988	15.866	EPSD	ICGC;COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	O43524	FOXO3	P27361	MAPK3	S344	D339N	339	Missense	distal	-5	no	17.722	17.716	EPSD;PhosphoSitePlus	ICGC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	O43524	FOXO3	P27361	MAPK3	S344	D339V	339	Missense	distal	-5	no	17.722	17.681	EPSD;PhosphoSitePlus	ICGC;COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	O43524	FOXO3	P27361	MAPK3	S402	S399F	399	Missense	distal	-3	no	15.143	15.002	EPSD	ICGC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	O43524	FOXO3	P27361	MAPK3	S413	P415L	415	Missense	proximal	2	no	9.925	9.903	EPSD	ICGC;COSMIC;GDSC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	O43524	FOXO3	P27361	MAPK3	S413	G420S	420	Missense	distal	7	no	9.925	9.786	EPSD	ICGC;COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	O43524	FOXO3	P27361	MAPK3	S413	F414L	414	Missense	proximal	1	no	9.925	7.101	EPSD	ICGC	9.358	Loss
CMGC_MAPK_ERK1_MAPK3_ST	O43524	FOXO3	P27361	MAPK3	S425	G424S	424	Missense	proximal	-1	no	16.864	16.930	EPSD;PhosphoSitePlus	ICGC;COSMIC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	O43524	FOXO3	P27361	MAPK3	S425	G420S	420	Missense	distal	-5	no	16.864	16.907	EPSD;PhosphoSitePlus	ICGC;COSMIC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	O43524	FOXO3	P27361	MAPK3	S425	S429Y	429	Missense	distal	4	no	16.864	16.648	EPSD;PhosphoSitePlus	ICGC;COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	O43524	FOXO3	P27361	MAPK3	S428	S429Y	429	Missense	proximal	1	no	8.435	10.440	EPSD	ICGC;COSMIC	9.358	Gain
CMGC_MAPK_ERK1_MAPK3_ST	O43524	FOXO3	P27361	MAPK3	S429	G424S	424	Missense	distal	-5	no	10.656	10.699	EPSD	ICGC;COSMIC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	O43524	FOXO3	P27361	MAPK3	S429	S429Y	429	Missense	central	0	yes	10.656	0.000	EPSD	ICGC;COSMIC	9.358	Loss
CMGC_MAPK_ERK1_MAPK3_ST	O43524	FOXO3	P27361	MAPK3	S446	N441K	441	Missense	distal	-5	no	15.312	15.306	EPSD	ICGC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	O43524	FOXO3	P27361	MAPK3	S446	S442F	442	Missense	distal	-4	no	15.312	15.123	EPSD	ICGC;COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	O43524	FOXO3	P27361	MAPK3	S667	S669I	669	Missense	proximal	2	no	11.953	11.918	EPSD	ICGC;COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	O43524	FOXO3	P27361	MAPK3	S669	S669I	669	Missense	central	0	yes	11.016	0.000	EPSD	ICGC;COSMIC	9.358	Loss
CMGC_MAPK_ERK1_MAPK3_ST	Q13115	DUSP4	P27361	MAPK3	S112	R114L	114	Missense	proximal	2	no	17.462	17.451	EPSD	ICGC;COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q13115	DUSP4	P27361	MAPK3	T188	S184R	184	Missense	distal	-4	no	11.851	11.774	EPSD	ICGC;COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q13115	DUSP4	P27361	MAPK3	T188	Q193R	193	Missense	distal	5	no	11.851	11.852	EPSD	ICGC;COSMIC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q13115	DUSP4	P27361	MAPK3	S318	G325W	325	Missense	distal	7	no	15.499	16.105	EPSD	ICGC;COSMIC;GDSC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q13115	DUSP4	P27361	MAPK3	S345	R351W	351	Missense	distal	6	no	15.420	14.597	EPSD	ICGC;COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q13115	DUSP4	P27361	MAPK3	S345	E342D	342	Missense	distal	-3	no	15.420	15.417	EPSD	ICGC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q13115	DUSP4	P27361	MAPK3	S345	P349L	349	Missense	distal	4	no	15.420	15.265	EPSD	ICGC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q13115	DUSP4	P27361	MAPK3	S345	A341V	341	Missense	distal	-4	no	15.420	15.400	EPSD	ICGC;COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q13115	DUSP4	P27361	MAPK3	S345	R351L	351	Missense	distal	6	no	15.420	15.305	EPSD	ICGC;COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q13115	DUSP4	P27361	MAPK3	T356	S362L	362	Missense	distal	6	no	13.385	13.029	EPSD	ICGC;COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q13115	DUSP4	P27361	MAPK3	T356	R351W	351	Missense	distal	-5	no	13.385	13.232	EPSD	ICGC;COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q13115	DUSP4	P27361	MAPK3	T356	P349L	349	Missense	distal	-7	no	13.385	13.493	EPSD	ICGC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q13115	DUSP4	P27361	MAPK3	T356	R351L	351	Missense	distal	-5	no	13.385	13.371	EPSD	ICGC;COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q13115	DUSP4	P27361	MAPK3	T359	S362L	362	Missense	distal	3	no	16.806	16.774	EPSD	ICGC;COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q13115	DUSP4	P27361	MAPK3	S367	S362L	362	Missense	distal	-5	no	11.751	11.692	EPSD	ICGC;COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q13115	DUSP4	P27361	MAPK3	S367	P369L	369	Missense	proximal	2	no	11.751	11.730	EPSD	ICGC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q13115	DUSP4	P27361	MAPK3	S371	P369L	369	Missense	proximal	-2	no	10.009	8.624	EPSD	ICGC	9.358	Loss
CMGC_MAPK_ERK1_MAPK3_ST	Q13115	DUSP4	P27361	MAPK3	S371	H375Q	375	Missense	distal	4	no	10.009	9.958	EPSD	ICGC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q13115	DUSP4	P27361	MAPK3	S376	P369L	369	Missense	distal	-7	no	9.397	9.504	EPSD	ICGC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q13115	DUSP4	P27361	MAPK3	S376	S380R	380	Missense	distal	4	no	9.397	9.250	EPSD	ICGC	9.358	Loss
CMGC_MAPK_ERK1_MAPK3_ST	Q13115	DUSP4	P27361	MAPK3	S376	P382L	382	Missense	distal	6	no	9.397	9.170	EPSD	ICGC;COSMIC	9.358	Loss
CMGC_MAPK_ERK1_MAPK3_ST	Q13115	DUSP4	P27361	MAPK3	S376	H375Q	375	Missense	proximal	-1	no	9.397	9.356	EPSD	ICGC	9.358	Loss
CMGC_MAPK_ERK1_MAPK3_ST	Q13115	DUSP4	P27361	MAPK3	S380	S380R	380	Missense	central	0	yes	10.090	0.000	EPSD	ICGC	9.358	Loss
CMGC_MAPK_ERK1_MAPK3_ST	Q13115	DUSP4	P27361	MAPK3	S380	P382L	382	Missense	proximal	2	no	10.090	10.068	EPSD	ICGC;COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q13115	DUSP4	P27361	MAPK3	S380	S386N	386	Missense	distal	6	no	10.090	9.861	EPSD	ICGC;COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q13115	DUSP4	P27361	MAPK3	S380	H375Q	375	Missense	distal	-5	no	10.090	10.073	EPSD	ICGC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q13115	DUSP4	P27361	MAPK3	S386	S380R	380	Missense	distal	-6	no	18.530	18.370	EPSD;PhosphoSitePlus	ICGC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q13115	DUSP4	P27361	MAPK3	S386	P382L	382	Missense	distal	-4	no	18.530	18.417	EPSD;PhosphoSitePlus	ICGC;COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q13115	DUSP4	P27361	MAPK3	S386	S393R	393	Missense	distal	7	no	18.530	18.700	EPSD;PhosphoSitePlus	ICGC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q13115	DUSP4	P27361	MAPK3	S386	S386N	386	Missense	central	0	yes	18.530	0.000	EPSD;PhosphoSitePlus	ICGC;COSMIC	9.358	Loss
CMGC_MAPK_ERK1_MAPK3_ST	Q13115	DUSP4	P27361	MAPK3	T389	P382L	382	Missense	distal	-7	no	10.026	10.134	EPSD	ICGC;COSMIC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q13115	DUSP4	P27361	MAPK3	T389	S393R	393	Missense	distal	4	no	10.026	9.880	EPSD	ICGC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q13115	DUSP4	P27361	MAPK3	T389	S386N	386	Missense	distal	-3	no	10.026	9.982	EPSD	ICGC;COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q13115	DUSP4	P27361	MAPK3	S391	S393R	393	Missense	proximal	2	no	19.378	19.365	PhosphoSitePlus;EPSD	ICGC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q13115	DUSP4	P27361	MAPK3	S391	S386N	386	Missense	distal	-5	no	19.378	19.337	PhosphoSitePlus;EPSD	ICGC;COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q9UHB6	LIMA1	P27361	MAPK3	S4	E2G	2	Missense	proximal	-2	no	16.033	15.563	EPSD	ICGC;COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q9UHB6	LIMA1	P27361	MAPK3	S4	P5L	5	Missense	proximal	1	no	16.033	6.995	EPSD	ICGC	9.358	Loss
CMGC_MAPK_ERK1_MAPK3_ST	Q9UHB6	LIMA1	P27361	MAPK3	S4	R9W	9	Missense	distal	5	no	16.033	15.565	EPSD	ICGC;COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q9UHB6	LIMA1	P27361	MAPK3	S132	H125N	125	Missense	distal	-7	no	15.907	15.902	EPSD	ICGC;COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q05209	PTPN12	P27361	MAPK3	S19	P20H	20	Missense	proximal	1	no	15.619	7.863	EPSD	ICGC;COSMIC	9.358	Loss
CMGC_MAPK_ERK1_MAPK3_ST	Q05209	PTPN12	P27361	MAPK3	S19	R13S	13	Missense	distal	-6	no	15.619	15.779	EPSD	ICGC;COSMIC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q05209	PTPN12	P27361	MAPK3	T81	Y88F	88	Missense	distal	7	no	15.493	15.729	EPSD	ICGC;COSMIC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q05209	PTPN12	P27361	MAPK3	T81	Q84H	84	Missense	distal	3	no	15.493	15.500	EPSD	ICGC;COSMIC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q05209	PTPN12	P27361	MAPK3	T81	D85G	85	Missense	distal	4	no	15.493	15.452	EPSD	ICGC;COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q05209	PTPN12	P27361	MAPK3	T81	V75A	75	Missense	distal	-6	no	15.493	15.506	EPSD	ICGC;COSMIC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q05209	PTPN12	P27361	MAPK3	T81	R74L	74	Missense	distal	-7	no	15.493	15.554	EPSD	ICGC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q05209	PTPN12	P27361	MAPK3	T569	S567T	567	Missense	proximal	-2	no	16.217	16.308	EPSD	ICGC;COSMIC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q05209	PTPN12	P27361	MAPK3	T569	Q575H	575	Missense	distal	6	no	16.217	16.306	EPSD	ICGC;COSMIC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q05209	PTPN12	P27361	MAPK3	S571	S567T	567	Missense	distal	-4	no	16.653	16.595	PhosphoSitePlus	ICGC;COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q05209	PTPN12	P27361	MAPK3	S571	Q575H	575	Missense	distal	4	no	16.653	16.703	PhosphoSitePlus	ICGC;COSMIC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q05209	PTPN12	P27361	MAPK3	T578	Q575H	575	Missense	distal	-3	no	13.705	13.719	EPSD	ICGC;COSMIC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q96Q27	ASB2	P27361	MAPK3	S28	E27K	27	Missense	proximal	-1	no	10.955	10.925	EPSD	ICGC;COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q96Q27	ASB2	P27361	MAPK3	S29	E27K	27	Missense	proximal	-2	no	17.534	16.840	EPSD	ICGC;COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P16949	STMN1	P27361	MAPK3	S25	L24F	24	Missense	proximal	-1	no	20.581	20.465	PhosphoSitePlus;EPSD	ICGC;COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P16949	STMN1	P27361	MAPK3	S25	E30K	30	Missense	distal	5	no	20.581	20.452	PhosphoSitePlus;EPSD	ICGC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P16949	STMN1	P27361	MAPK3	S25	E30Q	30	Missense	distal	5	no	20.581	20.459	PhosphoSitePlus;EPSD	ICGC;COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P16949	STMN1	P27361	MAPK3	S25	S31P	31	Missense	distal	6	no	20.581	20.451	PhosphoSitePlus;EPSD	ICGC;COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P16949	STMN1	P27361	MAPK3	S38	S31P	31	Missense	distal	-7	no	17.700	17.737	EPSD;PhosphoSitePlus	ICGC;COSMIC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q15746	MYLK	P27361	MAPK3	S259	V261A	261	Missense	proximal	2	no	9.463	9.450	EPSD	ICGC;COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q15746	MYLK	P27361	MAPK3	S259	T264K	264	Missense	distal	5	no	9.463	9.446	EPSD	ICGC;COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q15746	MYLK	P27361	MAPK3	S299	S299I	299	Missense	central	0	yes	13.189	0.000	EPSD	ICGC	9.358	Loss
CMGC_MAPK_ERK1_MAPK3_ST	Q15746	MYLK	P27361	MAPK3	S299	A292S	292	Missense	distal	-7	no	13.189	13.039	EPSD	ICGC;COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q15746	MYLK	P27361	MAPK3	S305	S299I	299	Missense	distal	-6	no	14.547	14.149	EPSD	ICGC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q15746	MYLK	P27361	MAPK3	S305	S312R	312	Missense	distal	7	no	14.547	14.717	EPSD	ICGC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q15746	MYLK	P27361	MAPK3	S328	Q334H	334	Missense	distal	6	no	15.316	15.405	EPSD	ICGC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q15746	MYLK	P27361	MAPK3	T335	T341S	341	Missense	distal	6	no	15.827	15.981	EPSD	ICGC;COSMIC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q15746	MYLK	P27361	MAPK3	T335	Q334H	334	Missense	proximal	-1	no	15.827	15.868	EPSD	ICGC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q15746	MYLK	P27361	MAPK3	S365	P359Q	359	Missense	distal	-6	no	17.290	17.224	EPSD	ICGC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q15746	MYLK	P27361	MAPK3	S365	A358E	358	Missense	distal	-7	no	17.290	17.173	EPSD	ICGC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q15746	MYLK	P27361	MAPK3	S515	P514S	514	Missense	proximal	-1	no	9.561	9.556	EPSD	ICGC;COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q15746	MYLK	P27361	MAPK3	S947	E942Q	942	Missense	distal	-5	no	16.192	16.174	EPSD	ICGC;COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q15746	MYLK	P27361	MAPK3	S947	R954S	954	Missense	distal	7	no	16.192	16.023	EPSD	ICGC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q15746	MYLK	P27361	MAPK3	S947	E941K	941	Missense	distal	-6	no	16.192	16.051	EPSD	ICGC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q15746	MYLK	P27361	MAPK3	T978	D980E	980	Missense	proximal	2	no	18.294	18.297	EPSD	ICGC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q15746	MYLK	P27361	MAPK3	S1156	S1154P	1154	Missense	proximal	-2	no	8.749	9.825	EPSD	ICGC	9.358	Gain
CMGC_MAPK_ERK1_MAPK3_ST	Q15746	MYLK	P27361	MAPK3	S1208	P1211A	1211	Missense	distal	3	no	9.454	9.405	EPSD	ICGC;COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q15746	MYLK	P27361	MAPK3	S1208	S1208I	1208	Missense	central	0	yes	9.454	0.000	EPSD	ICGC;COSMIC	9.358	Loss
CMGC_MAPK_ERK1_MAPK3_ST	Q15746	MYLK	P27361	MAPK3	S1208	R1204L	1204	Missense	distal	-4	no	9.454	9.391	EPSD	ICGC;COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q15746	MYLK	P27361	MAPK3	T1230	K1233T	1233	Missense	distal	3	no	16.362	16.373	EPSD	ICGC;COSMIC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q15746	MYLK	P27361	MAPK3	T1230	P1228H	1228	Missense	proximal	-2	no	16.362	15.135	EPSD	ICGC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q15746	MYLK	P27361	MAPK3	T1230	P1232T	1232	Missense	proximal	2	no	16.362	16.353	EPSD	ICGC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q15746	MYLK	P27361	MAPK3	T1230	T1230K	1230	Missense	central	0	yes	16.362	0.000	EPSD	ICGC	9.358	Loss
CMGC_MAPK_ERK1_MAPK3_ST	Q15746	MYLK	P27361	MAPK3	T1230	M1236V	1236	Missense	distal	6	no	16.362	16.573	EPSD	ICGC;COSMIC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q15746	MYLK	P27361	MAPK3	T1337	P1334L	1334	Missense	distal	-3	no	13.218	13.134	EPSD	ICGC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q15746	MYLK	P27361	MAPK3	T1337	P1331T	1331	Missense	distal	-6	no	13.218	13.134	EPSD	ICGC;COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q15746	MYLK	P27361	MAPK3	T1337	G1336D	1336	Missense	proximal	-1	no	13.218	13.237	EPSD	ICGC;COSMIC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q15746	MYLK	P27361	MAPK3	T1624	F1622S	1622	Missense	proximal	-2	no	12.363	13.663	EPSD	ICGC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q15746	MYLK	P27361	MAPK3	T1624	F1622V	1622	Missense	proximal	-2	no	12.363	13.085	EPSD	ICGC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q15746	MYLK	P27361	MAPK3	S1659	M1662V	1662	Missense	distal	3	no	14.109	14.133	EPSD	ICGC;COSMIC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	O75581	LRP6	P27361	MAPK3	S646	A640E	640	Missense	distal	-6	no	9.102	9.402	EPSD	ICGC	9.358	Gain
CMGC_MAPK_ERK1_MAPK3_ST	Q8IX03	WWC1	P27361	MAPK3	S257	R250C	250	Missense	distal	-7	no	9.171	9.358	EPSD	ICGC;COSMIC	9.358	Gain
CMGC_MAPK_ERK1_MAPK3_ST	Q8IX03	WWC1	P27361	MAPK3	S270	L266V	266	Missense	distal	-4	no	11.158	11.146	EPSD	ICGC;COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q8IX03	WWC1	P27361	MAPK3	S270	P274L	274	Missense	distal	4	no	11.158	11.004	EPSD	ICGC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q8IX03	WWC1	P27361	MAPK3	S270	Y277C	277	Missense	distal	7	no	11.158	11.515	EPSD	ICGC;COSMIC;CCLE	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q8IX03	WWC1	P27361	MAPK3	S270	S268I	268	Missense	proximal	-2	no	11.158	10.396	EPSD	ICGC;COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q8IX03	WWC1	P27361	MAPK3	S358	R355C	355	Missense	distal	-3	no	15.901	15.761	EPSD	ICGC;COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q8IX03	WWC1	P27361	MAPK3	S358	K352R	352	Missense	distal	-6	no	15.901	15.899	EPSD	ICGC;COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q8IX03	WWC1	P27361	MAPK3	S438	L442I	442	Missense	distal	4	no	16.373	16.236	EPSD	ICGC;COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q8IX03	WWC1	P27361	MAPK3	S441	L442I	442	Missense	proximal	1	no	11.099	10.630	EPSD	ICGC;COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q8IX03	WWC1	P27361	MAPK3	T527	T527I	527	Missense	central	0	yes	16.615	0.000	EPSD	ICGC;COSMIC	9.358	Loss
CMGC_MAPK_ERK1_MAPK3_ST	Q8IX03	WWC1	P27361	MAPK3	T527	A520S	520	Missense	distal	-7	no	16.615	16.465	EPSD	ICGC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q8IX03	WWC1	P27361	MAPK3	S535	P536Q	536	Missense	proximal	1	no	17.324	9.380	EPSD	ICGC;COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q8IX03	WWC1	P27361	MAPK3	S535	S539P	539	Missense	distal	4	no	17.324	17.275	EPSD	ICGC;COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q8IX03	WWC1	P27361	MAPK3	S535	S542T	542	Missense	distal	7	no	17.324	17.443	EPSD	ICGC;COSMIC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q8IX03	WWC1	P27361	MAPK3	S535	S535F	535	Missense	central	0	yes	17.324	0.000	EPSD	ICGC	9.358	Loss
CMGC_MAPK_ERK1_MAPK3_ST	Q8IX03	WWC1	P27361	MAPK3	S535	S541F	541	Missense	distal	6	no	17.324	16.611	EPSD	ICGC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q8IX03	WWC1	P27361	MAPK3	S542	P536Q	536	Missense	distal	-6	no	17.035	16.969	EPSD;PhosphoSitePlus	ICGC;COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q8IX03	WWC1	P27361	MAPK3	S542	S539P	539	Missense	distal	-3	no	17.035	17.044	EPSD;PhosphoSitePlus	ICGC;COSMIC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q8IX03	WWC1	P27361	MAPK3	S542	S535F	535	Missense	distal	-7	no	17.035	17.255	EPSD;PhosphoSitePlus	ICGC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q8IX03	WWC1	P27361	MAPK3	S542	S541F	541	Missense	proximal	-1	no	17.035	16.831	EPSD;PhosphoSitePlus	ICGC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q8IX03	WWC1	P27361	MAPK3	S548	L555V	555	Missense	distal	7	no	19.648	19.696	PhosphoSitePlus;EPSD	ICGC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q8IX03	WWC1	P27361	MAPK3	S548	P554L	554	Missense	distal	6	no	19.648	19.421	PhosphoSitePlus;EPSD	ICGC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q8IX03	WWC1	P27361	MAPK3	S548	S542T	542	Missense	distal	-6	no	19.648	19.480	PhosphoSitePlus;EPSD	ICGC;COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q8IX03	WWC1	P27361	MAPK3	S548	S541F	541	Missense	distal	-7	no	19.648	19.867	PhosphoSitePlus;EPSD	ICGC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q8IX03	WWC1	P27361	MAPK3	S876	M879R	879	Missense	distal	3	no	14.104	14.144	EPSD	ICGC;COSMIC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q8IX03	WWC1	P27361	MAPK3	T912	R908W	908	Missense	distal	-4	no	14.243	14.035	EPSD	ICGC;COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q8IX03	WWC1	P27361	MAPK3	T912	V910L	910	Missense	proximal	-2	no	14.243	14.513	EPSD	ICGC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q8IX03	WWC1	P27361	MAPK3	S914	R908W	908	Missense	distal	-6	no	9.490	8.967	EPSD	ICGC;COSMIC	9.358	Loss
CMGC_MAPK_ERK1_MAPK3_ST	Q8IX03	WWC1	P27361	MAPK3	S914	V910L	910	Missense	distal	-4	no	9.490	9.502	EPSD	ICGC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P11362	FGFR1	P27361	MAPK3	S91	G97S	97	Missense	distal	6	no	9.171	9.403	EPSD	ICGC;COSMIC	9.358	Gain
CMGC_MAPK_ERK1_MAPK3_ST	P11362	FGFR1	P27361	MAPK3	S433	S434F	434	Missense	proximal	1	no	6.808	9.648	EPSD	ICGC;COSMIC	9.358	Gain
CMGC_MAPK_ERK1_MAPK3_ST	O15525	MAFG	P27361	MAPK3	S124	A127V	127	Missense	distal	3	no	15.420	15.427	PhosphoSitePlus	ICGC;COSMIC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P14784	IL2RB	P27361	MAPK3	T282	P285H	285	Missense	distal	3	no	11.124	11.105	EPSD	ICGC;COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P14784	IL2RB	P27361	MAPK3	S431	L429F	429	Missense	proximal	-2	no	14.421	13.430	EPSD	ICGC;COSMIC;CCLE	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P14784	IL2RB	P27361	MAPK3	S431	D426E	426	Missense	distal	-5	no	14.421	14.422	EPSD	ICGC;COSMIC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P14784	IL2RB	P27361	MAPK3	S458	R465G	465	Missense	distal	7	no	9.727	9.697	EPSD	ICGC;COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P14784	IL2RB	P27361	MAPK3	S458	R465I	465	Missense	distal	7	no	9.727	9.956	EPSD	ICGC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P14784	IL2RB	P27361	MAPK3	S458	V463I	463	Missense	distal	5	no	9.727	9.601	EPSD	ICGC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P14784	IL2RB	P27361	MAPK3	T476	P471T	471	Missense	distal	-5	no	15.038	15.028	PhosphoSitePlus	ICGC;COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P14784	IL2RB	P27361	MAPK3	T476	P471L	471	Missense	distal	-5	no	15.038	14.984	PhosphoSitePlus	ICGC;COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P14784	IL2RB	P27361	MAPK3	T476	L472M	472	Missense	distal	-4	no	15.038	14.999	PhosphoSitePlus	ICGC;COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P14784	IL2RB	P27361	MAPK3	T533	L531M	531	Missense	proximal	-2	no	9.774	8.404	EPSD	ICGC;COSMIC	9.358	Loss
CMGC_MAPK_ERK1_MAPK3_ST	P14784	IL2RB	P27361	MAPK3	S538	Q545E	545	Missense	distal	7	no	10.159	10.064	EPSD	ICGC;COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P14784	IL2RB	P27361	MAPK3	S538	L531M	531	Missense	distal	-7	no	10.159	10.219	EPSD	ICGC;COSMIC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P06239	LCK	P27361	MAPK3	S75	G81V	81	Missense	distal	6	no	9.553	9.347	EPSD	ICGC	9.358	Loss
CMGC_MAPK_ERK1_MAPK3_ST	P06239	LCK	P27361	MAPK3	S281	S281N	281	Missense	central	0	yes	15.533	0.000	EPSD	ICGC;COSMIC	9.358	Loss
CMGC_MAPK_ERK1_MAPK3_ST	P06239	LCK	P27361	MAPK3	S281	S281I	281	Missense	central	0	yes	15.533	0.000	EPSD	ICGC	9.358	Loss
CMGC_MAPK_ERK1_MAPK3_ST	P06239	LCK	P27361	MAPK3	T501	E502D	502	Missense	proximal	1	no	11.178	11.825	EPSD	ICGC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P42702	LIFR	P27361	MAPK3	S368	A366D	366	Missense	proximal	-2	no	10.615	11.359	EPSD	ICGC;COSMIC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P42702	LIFR	P27361	MAPK3	S534	Q527K	527	Missense	distal	-7	no	17.155	17.157	EPSD	ICGC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P42702	LIFR	P27361	MAPK3	T904	N906D	906	Missense	proximal	2	no	15.727	15.732	EPSD	ICGC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P42702	LIFR	P27361	MAPK3	S927	E931G	931	Missense	distal	4	no	16.348	16.288	EPSD	ICGC;COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P42702	LIFR	P27361	MAPK3	S927	R932C	932	Missense	distal	5	no	16.348	15.969	EPSD	ICGC;COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P42702	LIFR	P27361	MAPK3	S927	E924K	924	Missense	distal	-3	no	16.348	16.317	EPSD	ICGC;COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P42702	LIFR	P27361	MAPK3	S927	V929A	929	Missense	proximal	2	no	16.348	16.335	EPSD	ICGC;COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P42702	LIFR	P27361	MAPK3	S1041	P1042Q	1042	Missense	proximal	1	no	17.599	9.655	EPSD	ICGC;COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P42702	LIFR	P27361	MAPK3	S1044	P1042Q	1042	Missense	proximal	-2	no	17.176	15.412	PhosphoSitePlus	ICGC;COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P42702	LIFR	P27361	MAPK3	S1056	P1060L	1060	Missense	distal	4	no	11.583	11.429	EPSD	ICGC;COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P42702	LIFR	P27361	MAPK3	S1059	P1060L	1060	Missense	proximal	1	no	16.075	7.037	EPSD	ICGC;COSMIC	9.358	Loss
CMGC_MAPK_ERK1_MAPK3_ST	P42702	LIFR	P27361	MAPK3	S1062	Q1067K	1067	Missense	distal	5	no	11.245	11.238	EPSD	ICGC;COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P42702	LIFR	P27361	MAPK3	S1062	P1060L	1060	Missense	proximal	-2	no	11.245	9.861	EPSD	ICGC;COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P42702	LIFR	P27361	MAPK3	S1077	P1071H	1071	Missense	distal	-6	no	17.669	17.589	EPSD	ICGC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P42702	LIFR	P27361	MAPK3	S1077	G1084R	1084	Missense	distal	7	no	17.669	17.700	EPSD	ICGC;COSMIC;GDSC;CCLE	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P42702	LIFR	P27361	MAPK3	S1086	Q1092E	1092	Missense	distal	6	no	12.169	12.349	EPSD	ICGC;COSMIC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P42702	LIFR	P27361	MAPK3	S1086	F1090I	1090	Missense	distal	4	no	12.169	12.243	EPSD	ICGC;COSMIC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P42702	LIFR	P27361	MAPK3	S1086	G1084R	1084	Missense	proximal	-2	no	12.169	12.886	EPSD	ICGC;COSMIC;GDSC;CCLE	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q14247	CTTN	P27361	MAPK3	T68	L69P	69	Missense	proximal	1	no	6.291	15.329	EPSD	ICGC	9.358	Gain
CMGC_MAPK_ERK1_MAPK3_ST	Q14247	CTTN	P27361	MAPK3	S277	A283V	283	Missense	distal	6	no	9.338	9.425	EPSD	ICGC;COSMIC	9.358	Gain
CMGC_MAPK_ERK1_MAPK3_ST	Q14247	CTTN	P27361	MAPK3	S277	E278D	278	Missense	proximal	1	no	9.338	9.985	EPSD	ICGC	9.358	Gain
CMGC_MAPK_ERK1_MAPK3_ST	Q14247	CTTN	P27361	MAPK3	S298	G305V	305	Missense	distal	7	no	9.430	9.609	EPSD	ICGC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q14247	CTTN	P27361	MAPK3	T401	T401M	401	Missense	central	0	yes	14.928	0.000	EPSD	ICGC;COSMIC	9.358	Loss
CMGC_MAPK_ERK1_MAPK3_ST	Q14247	CTTN	P27361	MAPK3	T401	T401A	401	Missense	central	0	yes	14.928	0.000	EPSD	ICGC	9.358	Loss
CMGC_MAPK_ERK1_MAPK3_ST	Q14247	CTTN	P27361	MAPK3	T401	S405L	405	Missense	distal	4	no	14.928	14.725	EPSD	ICGC;COSMIC;GDSC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q14247	CTTN	P27361	MAPK3	T401	A407T	407	Missense	distal	6	no	14.928	15.299	EPSD	ICGC;COSMIC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q14247	CTTN	P27361	MAPK3	S405	E412K	412	Missense	distal	7	no	18.528	18.599	PhosphoSitePlus;EPSD	ICGC;COSMIC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q14247	CTTN	P27361	MAPK3	S405	T401M	401	Missense	distal	-4	no	18.528	18.406	PhosphoSitePlus;EPSD	ICGC;COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q14247	CTTN	P27361	MAPK3	S405	T401A	401	Missense	distal	-4	no	18.528	18.454	PhosphoSitePlus;EPSD	ICGC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q14247	CTTN	P27361	MAPK3	S405	S405L	405	Missense	central	0	yes	18.528	0.000	PhosphoSitePlus;EPSD	ICGC;COSMIC;GDSC	9.358	Loss
CMGC_MAPK_ERK1_MAPK3_ST	Q14247	CTTN	P27361	MAPK3	S405	A407T	407	Missense	proximal	2	no	18.528	18.555	PhosphoSitePlus;EPSD	ICGC;COSMIC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q14247	CTTN	P27361	MAPK3	S418	E412K	412	Missense	distal	-6	no	18.198	18.056	EPSD;PhosphoSitePlus	ICGC;COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q14247	CTTN	P27361	MAPK3	S418	L415P	415	Missense	distal	-3	no	18.198	18.282	EPSD;PhosphoSitePlus	ICGC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q14247	CTTN	P27361	MAPK3	S418	A424V	424	Missense	distal	6	no	18.198	18.285	EPSD;PhosphoSitePlus	ICGC;COSMIC;GDSC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q14247	CTTN	P27361	MAPK3	S426	A424V	424	Missense	proximal	-2	no	11.240	11.936	EPSD	ICGC;COSMIC;GDSC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q14247	CTTN	P27361	MAPK3	S432	S438I	438	Missense	distal	6	no	9.815	9.245	EPSD	ICGC	9.358	Loss
CMGC_MAPK_ERK1_MAPK3_ST	Q08499	PDE4D	P27361	MAPK3	S18	G15A	15	Missense	distal	-3	no	10.692	10.633	EPSD	ICGC;COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q08499	PDE4D	P27361	MAPK3	S18	A12V	12	Missense	distal	-6	no	10.692	10.679	EPSD	ICGC;COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q08499	PDE4D	P27361	MAPK3	S18	A24V	24	Missense	distal	6	no	10.692	10.779	EPSD	ICGC;COSMIC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q08499	PDE4D	P27361	MAPK3	S171	I177V	177	Missense	distal	6	no	15.078	15.209	EPSD	ICGC;COSMIC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q08499	PDE4D	P27361	MAPK3	S202	D196E	196	Missense	distal	-6	no	16.308	16.353	EPSD	ICGC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q08499	PDE4D	P27361	MAPK3	S202	N209S	209	Missense	distal	7	no	16.308	16.143	EPSD	ICGC;COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q08499	PDE4D	P27361	MAPK3	S202	Y199C	199	Missense	distal	-3	no	16.308	16.194	EPSD	ICGC;GDSC;CCLE	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q08499	PDE4D	P27361	MAPK3	S211	N209S	209	Missense	proximal	-2	no	8.696	9.641	EPSD	ICGC;COSMIC	9.358	Gain
CMGC_MAPK_ERK1_MAPK3_ST	Q08499	PDE4D	P27361	MAPK3	T224	D220E	220	Missense	distal	-4	no	13.622	13.633	EPSD	ICGC;COSMIC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q08499	PDE4D	P27361	MAPK3	T224	H217N	217	Missense	distal	-7	no	13.622	13.617	EPSD	ICGC;COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q08499	PDE4D	P27361	MAPK3	S255	Q260K	260	Missense	distal	5	no	15.109	15.102	EPSD	ICGC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q08499	PDE4D	P27361	MAPK3	S255	S252R	252	Missense	distal	-3	no	15.109	15.071	EPSD	ICGC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q08499	PDE4D	P27361	MAPK3	S255	P251H	251	Missense	distal	-4	no	15.109	15.073	EPSD	ICGC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q08499	PDE4D	P27361	MAPK3	T336	N335K	335	Missense	proximal	-1	no	11.009	11.003	EPSD	ICGC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q08499	PDE4D	P27361	MAPK3	S362	Q363E	363	Missense	proximal	1	no	11.284	9.980	EPSD	ICGC;COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q08499	PDE4D	P27361	MAPK3	S362	P360Q	360	Missense	proximal	-2	no	11.284	9.520	EPSD	ICGC;COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q08499	PDE4D	P27361	MAPK3	S657	R652H	652	Missense	distal	-5	no	15.411	15.420	EPSD	ICGC;COSMIC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q08499	PDE4D	P27361	MAPK3	S657	M654V	654	Missense	distal	-3	no	15.411	15.466	EPSD	ICGC;COSMIC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q08499	PDE4D	P27361	MAPK3	S657	H663N	663	Missense	distal	6	no	15.411	15.405	EPSD	ICGC;COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q08499	PDE4D	P27361	MAPK3	S715	S715N	715	Missense	central	0	yes	20.327	0.000	EPSD	ICGC	9.358	Loss
CMGC_MAPK_ERK1_MAPK3_ST	Q08499	PDE4D	P27361	MAPK3	S717	S715N	715	Missense	proximal	-2	no	14.599	13.655	EPSD	ICGC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q08499	PDE4D	P27361	MAPK3	S717	P723Q	723	Missense	distal	6	no	14.599	14.418	EPSD	ICGC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	O95644	NFATC1	P27361	MAPK3	S117	S124L	124	Missense	distal	7	no	16.395	16.665	EPSD	ICGC;COSMIC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	O95644	NFATC1	P27361	MAPK3	S117	R119H	119	Missense	proximal	2	no	16.395	16.392	EPSD	ICGC;COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	O95644	NFATC1	P27361	MAPK3	S117	E121K	121	Missense	distal	4	no	16.395	16.357	EPSD	ICGC;COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	O95644	NFATC1	P27361	MAPK3	S151	T154M	154	Missense	distal	3	no	13.591	13.543	EPSD	ICGC;COSMIC;CCLE	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	O95644	NFATC1	P27361	MAPK3	S151	S151P	151	Missense	central	0	yes	13.591	0.000	EPSD	ICGC;COSMIC	9.358	Loss
CMGC_MAPK_ERK1_MAPK3_ST	O95644	NFATC1	P27361	MAPK3	S151	S158R	158	Missense	distal	7	no	13.591	13.761	EPSD	ICGC;COSMIC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	O95644	NFATC1	P27361	MAPK3	S151	S151C	151	Missense	central	0	yes	13.591	0.000	EPSD	ICGC;COSMIC	9.358	Loss
CMGC_MAPK_ERK1_MAPK3_ST	O95644	NFATC1	P27361	MAPK3	S151	R150L	150	Missense	proximal	-1	no	13.591	13.544	EPSD	ICGC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	O95644	NFATC1	P27361	MAPK3	S151	A155S	155	Missense	distal	4	no	13.591	13.922	EPSD	ICGC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	O95644	NFATC1	P27361	MAPK3	S151	P152L	152	Missense	proximal	1	no	13.591	4.553	EPSD	ICGC;COSMIC	9.358	Loss
CMGC_MAPK_ERK1_MAPK3_ST	O95644	NFATC1	P27361	MAPK3	S151	P146S	146	Missense	distal	-5	no	13.591	13.596	EPSD	ICGC;COSMIC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	O95644	NFATC1	P27361	MAPK3	S151	V144I	144	Missense	distal	-7	no	13.591	13.633	EPSD	ICGC;COSMIC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	O95644	NFATC1	P27361	MAPK3	S151	T156M	156	Missense	distal	5	no	13.591	13.336	EPSD	ICGC;COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	O95644	NFATC1	P27361	MAPK3	S151	R150W	150	Missense	proximal	-1	no	13.591	13.353	EPSD	ICGC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	O95644	NFATC1	P27361	MAPK3	S172	A174T	174	Missense	proximal	2	no	13.563	13.591	PhosphoSitePlus	ICGC;COSMIC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	O95644	NFATC1	P27361	MAPK3	S172	L177M	177	Missense	distal	5	no	13.563	13.443	PhosphoSitePlus	ICGC;COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	O95644	NFATC1	P27361	MAPK3	S172	L171P	171	Missense	proximal	-1	no	13.563	13.658	PhosphoSitePlus	ICGC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	O95644	NFATC1	P27361	MAPK3	S172	A174V	174	Missense	proximal	2	no	13.563	13.576	PhosphoSitePlus	ICGC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	O95644	NFATC1	P27361	MAPK3	S172	S176N	176	Missense	distal	4	no	13.563	13.417	PhosphoSitePlus	ICGC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	O95644	NFATC1	P27361	MAPK3	S172	D167Y	167	Missense	distal	-5	no	13.563	13.534	PhosphoSitePlus	ICGC;COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	O95644	NFATC1	P27361	MAPK3	S175	S181N	181	Missense	distal	6	no	9.388	9.159	EPSD	ICGC;COSMIC	9.358	Loss
CMGC_MAPK_ERK1_MAPK3_ST	O95644	NFATC1	P27361	MAPK3	S175	A174T	174	Missense	proximal	-1	no	9.388	9.491	EPSD	ICGC;COSMIC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	O95644	NFATC1	P27361	MAPK3	S175	C182R	182	Missense	distal	7	no	9.388	8.946	EPSD	ICGC	9.358	Loss
CMGC_MAPK_ERK1_MAPK3_ST	O95644	NFATC1	P27361	MAPK3	S175	L177M	177	Missense	proximal	2	no	9.388	9.368	EPSD	ICGC;COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	O95644	NFATC1	P27361	MAPK3	S175	L171P	171	Missense	distal	-4	no	9.388	9.501	EPSD	ICGC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	O95644	NFATC1	P27361	MAPK3	S175	A174V	174	Missense	proximal	-1	no	9.388	9.438	EPSD	ICGC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	O95644	NFATC1	P27361	MAPK3	S175	S176N	176	Missense	proximal	1	no	9.388	4.353	EPSD	ICGC	9.358	Loss
CMGC_MAPK_ERK1_MAPK3_ST	O95644	NFATC1	P27361	MAPK3	S211	V210M	210	Missense	proximal	-1	no	13.644	13.573	EPSD	ICGC;COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	O95644	NFATC1	P27361	MAPK3	S211	V210L	210	Missense	proximal	-1	no	13.644	13.640	EPSD	ICGC;COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	O95644	NFATC1	P27361	MAPK3	S211	P208S	208	Missense	distal	-3	no	13.644	13.636	EPSD	ICGC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	O95644	NFATC1	P27361	MAPK3	S211	P208L	208	Missense	distal	-3	no	13.644	13.560	EPSD	ICGC;COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	O95644	NFATC1	P27361	MAPK3	S233	G232C	232	Missense	proximal	-1	no	16.952	16.792	EPSD	ICGC;COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	O95644	NFATC1	P27361	MAPK3	S233	P234L	234	Missense	proximal	1	no	16.952	7.914	EPSD	ICGC;COSMIC	9.358	Loss
CMGC_MAPK_ERK1_MAPK3_ST	O95644	NFATC1	P27361	MAPK3	S237	A244T	244	Missense	distal	7	no	13.662	13.435	EPSD	ICGC;COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	O95644	NFATC1	P27361	MAPK3	S237	P242S	242	Missense	distal	5	no	13.662	13.705	EPSD	ICGC;COSMIC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	O95644	NFATC1	P27361	MAPK3	S237	G232C	232	Missense	distal	-5	no	13.662	13.543	EPSD	ICGC;COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	O95644	NFATC1	P27361	MAPK3	S237	P242L	242	Missense	distal	5	no	13.662	13.434	EPSD	ICGC;COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	O95644	NFATC1	P27361	MAPK3	S237	P234L	234	Missense	distal	-3	no	13.662	13.578	EPSD	ICGC;COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	O95644	NFATC1	P27361	MAPK3	S241	A244T	244	Missense	distal	3	no	16.639	16.670	EPSD	ICGC;COSMIC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	O95644	NFATC1	P27361	MAPK3	S241	V246L	246	Missense	distal	5	no	16.639	16.635	EPSD	ICGC;COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	O95644	NFATC1	P27361	MAPK3	S241	P242S	242	Missense	proximal	1	no	16.639	7.586	EPSD	ICGC;COSMIC	9.358	Loss
CMGC_MAPK_ERK1_MAPK3_ST	O95644	NFATC1	P27361	MAPK3	S241	V246I	246	Missense	distal	5	no	16.639	16.513	EPSD	ICGC;COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	O95644	NFATC1	P27361	MAPK3	S241	P242L	242	Missense	proximal	1	no	16.639	7.601	EPSD	ICGC;COSMIC	9.358	Loss
CMGC_MAPK_ERK1_MAPK3_ST	O95644	NFATC1	P27361	MAPK3	S241	P234L	234	Missense	distal	-7	no	16.639	16.746	EPSD	ICGC;COSMIC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	O95644	NFATC1	P27361	MAPK3	S261	P262L	262	Missense	proximal	1	no	16.253	7.215	EPSD	ICGC;COSMIC	9.358	Loss
CMGC_MAPK_ERK1_MAPK3_ST	O95644	NFATC1	P27361	MAPK3	S278	R273L	273	Missense	distal	-5	no	18.844	18.830	EPSD	ICGC;COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	O95644	NFATC1	P27361	MAPK3	S278	H281D	281	Missense	distal	3	no	18.844	18.848	EPSD	ICGC;COSMIC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	O95644	NFATC1	P27361	MAPK3	S278	G272V	272	Missense	distal	-6	no	18.844	18.577	EPSD	ICGC;COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	O95644	NFATC1	P27361	MAPK3	S278	P275S	275	Missense	distal	-3	no	18.844	18.836	EPSD	ICGC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	O95644	NFATC1	P27361	MAPK3	S278	P276A	276	Missense	proximal	-2	no	18.844	16.493	EPSD	ICGC;COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	O95644	NFATC1	P27361	MAPK3	S278	R273Q	273	Missense	distal	-5	no	18.844	18.837	EPSD	ICGC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	O95644	NFATC1	P27361	MAPK3	S278	H280Y	280	Missense	proximal	2	no	18.844	18.838	EPSD	ICGC;COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	O95644	NFATC1	P27361	MAPK3	S282	H281D	281	Missense	proximal	-1	no	17.928	17.921	EPSD	ICGC;COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	O95644	NFATC1	P27361	MAPK3	S282	P275S	275	Missense	distal	-7	no	17.928	17.891	EPSD	ICGC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	O95644	NFATC1	P27361	MAPK3	S282	P276A	276	Missense	distal	-6	no	17.928	17.696	EPSD	ICGC;COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	O95644	NFATC1	P27361	MAPK3	S282	S286P	286	Missense	distal	4	no	17.928	17.879	EPSD	ICGC;COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	O95644	NFATC1	P27361	MAPK3	S282	H280Y	280	Missense	proximal	-2	no	17.928	17.847	EPSD	ICGC;COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	O95644	NFATC1	P27361	MAPK3	S282	G289S	289	Missense	distal	7	no	17.928	17.789	EPSD	ICGC;COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	O95644	NFATC1	P27361	MAPK3	T284	H281D	281	Missense	distal	-3	no	16.135	16.144	EPSD	ICGC;COSMIC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	O95644	NFATC1	P27361	MAPK3	T284	S286P	286	Missense	proximal	2	no	16.135	16.133	EPSD	ICGC;COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	O95644	NFATC1	P27361	MAPK3	T284	S290F	290	Missense	distal	6	no	16.135	15.421	EPSD	ICGC;COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	O95644	NFATC1	P27361	MAPK3	T284	H280Y	280	Missense	distal	-4	no	16.135	16.095	EPSD	ICGC;COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	O95644	NFATC1	P27361	MAPK3	T284	P291T	291	Missense	distal	7	no	16.135	16.176	EPSD	ICGC;COSMIC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	O95644	NFATC1	P27361	MAPK3	T284	G289S	289	Missense	distal	5	no	16.135	16.200	EPSD	ICGC;COSMIC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	O95644	NFATC1	P27361	MAPK3	S286	H281D	281	Missense	distal	-5	no	14.954	14.956	EPSD	ICGC;COSMIC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	O95644	NFATC1	P27361	MAPK3	S286	S286P	286	Missense	central	0	yes	14.954	0.000	EPSD	ICGC;COSMIC	9.358	Loss
CMGC_MAPK_ERK1_MAPK3_ST	O95644	NFATC1	P27361	MAPK3	S286	S290F	290	Missense	distal	4	no	14.954	14.540	EPSD	ICGC;COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	O95644	NFATC1	P27361	MAPK3	S286	H280Y	280	Missense	distal	-6	no	14.954	14.865	EPSD	ICGC;COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	O95644	NFATC1	P27361	MAPK3	S286	P291T	291	Missense	distal	5	no	14.954	14.861	EPSD	ICGC;COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	O95644	NFATC1	P27361	MAPK3	S286	G289S	289	Missense	distal	3	no	14.954	14.969	EPSD	ICGC;COSMIC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	O95644	NFATC1	P27361	MAPK3	S290	V295M	295	Missense	distal	5	no	17.580	17.456	EPSD	ICGC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	O95644	NFATC1	P27361	MAPK3	S290	D297Y	297	Missense	distal	7	no	17.580	17.728	EPSD	ICGC;COSMIC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	O95644	NFATC1	P27361	MAPK3	S290	S286P	286	Missense	distal	-4	no	17.580	17.553	EPSD	ICGC;COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	O95644	NFATC1	P27361	MAPK3	S290	T296I	296	Missense	distal	6	no	17.580	17.165	EPSD	ICGC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	O95644	NFATC1	P27361	MAPK3	S290	S290F	290	Missense	central	0	yes	17.580	0.000	EPSD	ICGC;COSMIC	9.358	Loss
CMGC_MAPK_ERK1_MAPK3_ST	O95644	NFATC1	P27361	MAPK3	S290	P291T	291	Missense	proximal	1	no	17.580	8.703	EPSD	ICGC;COSMIC	9.358	Loss
CMGC_MAPK_ERK1_MAPK3_ST	O95644	NFATC1	P27361	MAPK3	S290	G289S	289	Missense	proximal	-1	no	17.580	17.646	EPSD	ICGC;COSMIC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	O95644	NFATC1	P27361	MAPK3	S345	S345L	345	Missense	central	0	yes	10.342	0.000	EPSD	ICGC;COSMIC	9.358	Loss
CMGC_MAPK_ERK1_MAPK3_ST	O95644	NFATC1	P27361	MAPK3	S345	A347V	347	Missense	proximal	2	no	10.342	10.356	EPSD	ICGC;COSMIC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	O95644	NFATC1	P27361	MAPK3	S345	E341D	341	Missense	distal	-4	no	10.342	10.331	EPSD	ICGC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	O95644	NFATC1	P27361	MAPK3	S359	P362L	362	Missense	distal	3	no	16.717	16.680	EPSD	ICGC;COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	O95644	NFATC1	P27361	MAPK3	S359	G354E	354	Missense	distal	-5	no	16.717	16.726	EPSD	ICGC;COSMIC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	O95644	NFATC1	P27361	MAPK3	S359	P361L	361	Missense	proximal	2	no	16.717	16.695	EPSD	ICGC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	O95644	NFATC1	P27361	MAPK3	S359	P363S	363	Missense	distal	4	no	16.717	16.766	EPSD	ICGC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	O95644	NFATC1	P27361	MAPK3	S359	A364G	364	Missense	distal	5	no	16.717	16.907	EPSD	ICGC;COSMIC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	O95644	NFATC1	P27361	MAPK3	S373	A367V	367	Missense	distal	-6	no	9.537	9.524	EPSD	ICGC;COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	O95644	NFATC1	P27361	MAPK3	S373	G380D	380	Missense	distal	7	no	9.537	9.504	EPSD	ICGC;COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	O95644	NFATC1	P27361	MAPK3	S403	A397V	397	Missense	distal	-6	no	17.502	17.489	EPSD	ICGC;COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	O95644	NFATC1	P27361	MAPK3	S403	P410T	410	Missense	distal	7	no	17.502	17.543	EPSD	ICGC;COSMIC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	O95644	NFATC1	P27361	MAPK3	S403	P404S	404	Missense	proximal	1	no	17.502	8.448	EPSD	ICGC;COSMIC	9.358	Loss
CMGC_MAPK_ERK1_MAPK3_ST	O95644	NFATC1	P27361	MAPK3	S403	S409R	409	Missense	distal	6	no	17.502	17.260	EPSD	ICGC;COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	O95644	NFATC1	P27361	MAPK3	S409	P410T	410	Missense	proximal	1	no	14.915	6.038	EPSD	ICGC;COSMIC	9.358	Loss
CMGC_MAPK_ERK1_MAPK3_ST	O95644	NFATC1	P27361	MAPK3	S409	P404S	404	Missense	distal	-5	no	14.915	14.920	EPSD	ICGC;COSMIC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	O95644	NFATC1	P27361	MAPK3	S409	P413S	413	Missense	distal	4	no	14.915	14.964	EPSD	ICGC;COSMIC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	O95644	NFATC1	P27361	MAPK3	S409	S409R	409	Missense	central	0	yes	14.915	0.000	EPSD	ICGC;COSMIC	9.358	Loss
CMGC_MAPK_ERK1_MAPK3_ST	O95644	NFATC1	P27361	MAPK3	S506	S506N	506	Missense	central	0	yes	10.807	0.000	EPSD	ICGC	9.358	Loss
CMGC_MAPK_ERK1_MAPK3_ST	O95644	NFATC1	P27361	MAPK3	S506	V502L	502	Missense	distal	-4	no	10.807	10.819	EPSD	ICGC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	O95644	NFATC1	P27361	MAPK3	S506	S512F	512	Missense	distal	6	no	10.807	10.093	EPSD	ICGC;CCLE	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	O95644	NFATC1	P27361	MAPK3	S506	G499W	499	Missense	distal	-7	no	10.807	11.098	EPSD	ICGC;COSMIC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	O95644	NFATC1	P27361	MAPK3	S506	E508K	508	Missense	proximal	2	no	10.807	10.800	EPSD	ICGC;COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	O95644	NFATC1	P27361	MAPK3	S670	R667S	667	Missense	distal	-3	no	17.270	17.308	EPSD	ICGC;COSMIC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	O95644	NFATC1	P27361	MAPK3	S670	V674I	674	Missense	distal	4	no	17.270	17.152	EPSD	ICGC;COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	O95644	NFATC1	P27361	MAPK3	S670	V672F	672	Missense	proximal	2	no	17.270	17.245	EPSD	ICGC;COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	O95644	NFATC1	P27361	MAPK3	S670	V674F	674	Missense	distal	4	no	17.270	17.079	EPSD	ICGC;COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	O95644	NFATC1	P27361	MAPK3	S670	S670N	670	Missense	central	0	yes	17.270	0.000	EPSD	ICGC;COSMIC	9.358	Loss
CMGC_MAPK_ERK1_MAPK3_ST	O95644	NFATC1	P27361	MAPK3	S675	K682T	682	Missense	distal	7	no	10.462	10.406	EPSD	ICGC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	O95644	NFATC1	P27361	MAPK3	S675	V674I	674	Missense	proximal	-1	no	10.462	10.415	EPSD	ICGC;COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	O95644	NFATC1	P27361	MAPK3	S675	V672F	672	Missense	distal	-3	no	10.462	10.393	EPSD	ICGC;COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	O95644	NFATC1	P27361	MAPK3	S675	V674F	674	Missense	proximal	-1	no	10.462	10.342	EPSD	ICGC;COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	O95644	NFATC1	P27361	MAPK3	S675	S670N	670	Missense	distal	-5	no	10.462	10.422	EPSD	ICGC;COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	O95644	NFATC1	P27361	MAPK3	S675	V678I	678	Missense	distal	3	no	10.462	10.448	EPSD	ICGC;COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	O95644	NFATC1	P27361	MAPK3	S887	A890D	890	Missense	distal	3	no	15.808	15.842	EPSD	ICGC;COSMIC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	O95644	NFATC1	P27361	MAPK3	S887	R893Q	893	Missense	distal	6	no	15.808	15.739	EPSD	ICGC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	O95644	NFATC1	P27361	MAPK3	S887	R883C	883	Missense	distal	-4	no	15.808	15.647	EPSD	ICGC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	O95644	NFATC1	P27361	MAPK3	S903	P910L	910	Missense	distal	7	no	16.396	16.589	EPSD	ICGC;COSMIC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P04637	TP53	P27361	MAPK3	S15	E11K	11	Missense	distal	-4	no	12.832	12.772	EPSD;PhosphoSitePlus	ICGC;COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P04637	TP53	P27361	MAPK3	T18	E11K	11	Missense	distal	-7	no	10.342	10.393	EPSD	ICGC;COSMIC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P04637	TP53	P27361	MAPK3	T18	W23C	23	Missense	distal	5	no	10.342	10.430	EPSD	ICGC;COSMIC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P04637	TP53	P27361	MAPK3	S20	W23C	23	Missense	distal	3	no	10.750	10.765	EPSD	ICGC;COSMIC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P04637	TP53	P27361	MAPK3	S33	P34L	34	Missense	proximal	1	no	15.325	6.287	EPSD	ICGC;COSMIC	9.358	Loss
CMGC_MAPK_ERK1_MAPK3_ST	P04637	TP53	P27361	MAPK3	S33	S33F	33	Missense	central	0	yes	15.325	0.000	EPSD	ICGC;COSMIC	9.358	Loss
CMGC_MAPK_ERK1_MAPK3_ST	P04637	TP53	P27361	MAPK3	S33	N30I	30	Missense	distal	-3	no	15.325	15.258	EPSD	ICGC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P04637	TP53	P27361	MAPK3	S46	D48G	48	Missense	proximal	2	no	14.562	14.556	EPSD	ICGC;COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P04637	TP53	P27361	MAPK3	S46	Q52K	52	Missense	distal	6	no	14.562	14.665	EPSD	ICGC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P04637	TP53	P27361	MAPK3	T81	A88D	88	Missense	distal	7	no	16.918	16.679	EPSD	ICGC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P04637	TP53	P27361	MAPK3	T81	P87Q	87	Missense	distal	6	no	16.918	16.737	EPSD	ICGC;COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P04637	TP53	P27361	MAPK3	S127	T125R	125	Missense	proximal	-2	no	16.318	15.904	EPSD	ICGC;COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P04637	TP53	P27361	MAPK3	S127	F134C	134	Missense	distal	7	no	16.318	16.439	EPSD	ICGC;COSMIC;CCLE	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P04637	TP53	P27361	MAPK3	S127	C124G	124	Missense	distal	-3	no	16.318	16.463	EPSD	ICGC;COSMIC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P04637	TP53	P27361	MAPK3	S127	C124R	124	Missense	distal	-3	no	16.318	16.458	EPSD	ICGC;COSMIC;GDSC;CCLE	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P04637	TP53	P27361	MAPK3	S127	L130H	130	Missense	distal	3	no	16.318	16.336	EPSD	ICGC;COSMIC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P04637	TP53	P27361	MAPK3	S127	T125A	125	Missense	proximal	-2	no	16.318	14.953	EPSD	ICGC;COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P04637	TP53	P27361	MAPK3	S127	K120N	120	Missense	distal	-7	no	16.318	16.301	EPSD	ICGC;COSMIC;GDSC;CCLE	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P04637	TP53	P27361	MAPK3	S127	N131Y	131	Missense	distal	4	no	16.318	16.248	EPSD	ICGC;COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P04637	TP53	P27361	MAPK3	S127	K120M	120	Missense	distal	-7	no	16.318	16.439	EPSD	ICGC;COSMIC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P04637	TP53	P27361	MAPK3	S127	K132M	132	Missense	distal	5	no	16.318	16.079	EPSD	ICGC;COSMIC;CCLE	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P04637	TP53	P27361	MAPK3	S127	M133T	133	Missense	distal	6	no	16.318	16.812	EPSD	ICGC;COSMIC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P04637	TP53	P27361	MAPK3	S127	K120R	120	Missense	distal	-7	no	16.318	16.317	EPSD	ICGC;COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P04637	TP53	P27361	MAPK3	S127	C124Y	124	Missense	distal	-3	no	16.318	16.432	EPSD	ICGC;COSMIC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P04637	TP53	P27361	MAPK3	T150	R156L	156	Missense	distal	6	no	12.555	12.440	EPSD	ICGC;COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P04637	TP53	P27361	MAPK3	T150	L145Q	145	Missense	distal	-5	no	12.555	12.562	EPSD	ICGC;COSMIC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P04637	TP53	P27361	MAPK3	T150	P152R	152	Missense	proximal	2	no	12.555	12.545	EPSD	ICGC;COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P04637	TP53	P27361	MAPK3	T150	G154S	154	Missense	distal	4	no	12.555	12.716	EPSD	ICGC;COSMIC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P04637	TP53	P27361	MAPK3	T150	V157A	157	Missense	distal	7	no	12.555	12.583	EPSD	ICGC;COSMIC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P04637	TP53	P27361	MAPK3	T150	P151F	151	Missense	proximal	1	no	12.555	6.341	EPSD	ICGC;COSMIC	9.358	Loss
CMGC_MAPK_ERK1_MAPK3_ST	P04637	TP53	P27361	MAPK3	T150	V147G	147	Missense	distal	-3	no	12.555	12.595	EPSD	ICGC;COSMIC;GDSC;CCLE	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P04637	TP53	P27361	MAPK3	S315	T312I	312	Missense	distal	-3	no	16.542	16.461	EPSD	ICGC;COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P04637	TP53	P27361	MAPK3	S315	P322T	322	Missense	distal	7	no	16.542	16.583	EPSD	ICGC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P04637	TP53	P27361	MAPK3	S367	G374C	374	Missense	distal	7	no	10.558	11.031	EPSD	ICGC;COSMIC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P04637	TP53	P27361	MAPK3	S376	T377P	377	Missense	proximal	1	no	10.149	19.026	EPSD	ICGC;COSMIC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P04637	TP53	P27361	MAPK3	S376	G374C	374	Missense	proximal	-2	no	10.149	8.749	EPSD	ICGC;COSMIC	9.358	Loss
CMGC_MAPK_ERK1_MAPK3_ST	P04637	TP53	P27361	MAPK3	S376	R379S	379	Missense	distal	3	no	10.149	10.171	EPSD	ICGC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P04637	TP53	P27361	MAPK3	S376	R379C	379	Missense	distal	3	no	10.149	10.086	EPSD	ICGC;COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P04637	TP53	P27361	MAPK3	S378	T377P	377	Missense	proximal	-1	no	9.499	9.535	EPSD	ICGC;COSMIC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P04637	TP53	P27361	MAPK3	S378	F385L	385	Missense	distal	7	no	9.499	9.278	EPSD	ICGC;COSMIC	9.358	Loss
CMGC_MAPK_ERK1_MAPK3_ST	P04637	TP53	P27361	MAPK3	S378	G374C	374	Missense	distal	-4	no	9.499	9.300	EPSD	ICGC;COSMIC	9.358	Loss
CMGC_MAPK_ERK1_MAPK3_ST	P04637	TP53	P27361	MAPK3	S378	R379S	379	Missense	proximal	1	no	9.499	9.946	EPSD	ICGC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P04637	TP53	P27361	MAPK3	S378	R379C	379	Missense	proximal	1	no	9.499	3.692	EPSD	ICGC;COSMIC	9.358	Loss
CMGC_MAPK_ERK1_MAPK3_ST	P04637	TP53	P27361	MAPK3	T387	F385L	385	Missense	proximal	-2	no	8.623	9.615	EPSD	ICGC;COSMIC	9.358	Gain
CMGC_MAPK_ERK1_MAPK3_ST	P04637	TP53	P27361	MAPK3	S392	F385L	385	Missense	distal	-7	no	10.933	10.858	PhosphoSitePlus;EPSD	ICGC;COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P27708	CAD	P27361	MAPK3	T456	H458Q	458	Missense	proximal	2	no	16.501	16.495	PhosphoSitePlus	ICGC;COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P27708	CAD	P27361	MAPK3	T456	V460A	460	Missense	distal	4	no	16.501	16.394	PhosphoSitePlus	ICGC;COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P27708	CAD	P27361	MAPK3	T504	G498V	498	Missense	distal	-6	no	14.150	13.883	EPSD	ICGC;COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P27708	CAD	P27361	MAPK3	T504	R500Q	500	Missense	distal	-4	no	14.150	14.160	EPSD	ICGC;COSMIC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P27708	CAD	P27361	MAPK3	T504	R500W	500	Missense	distal	-4	no	14.150	13.942	EPSD	ICGC;COSMIC;GDSC;CCLE	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P27708	CAD	P27361	MAPK3	S586	D591E	591	Missense	distal	5	no	10.028	10.047	EPSD	ICGC;COSMIC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P27708	CAD	P27361	MAPK3	S586	T585S	585	Missense	proximal	-1	no	10.028	10.059	EPSD	ICGC;COSMIC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P27708	CAD	P27361	MAPK3	S586	A581D	581	Missense	distal	-5	no	10.028	10.093	EPSD	ICGC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P27708	CAD	P27361	MAPK3	S1267	R1270W	1270	Missense	distal	3	no	11.697	11.619	EPSD	ICGC;COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q969H0	FBXW7	P27361	MAPK3	S25	R20I	20	Missense	distal	-5	no	12.931	12.882	EPSD	ICGC;COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q969H0	FBXW7	P27361	MAPK3	S25	P23S	23	Missense	proximal	-2	no	12.931	11.855	EPSD	ICGC;COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q969H0	FBXW7	P27361	MAPK3	S26	R20I	20	Missense	distal	-6	no	12.241	12.003	EPSD	ICGC;COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q969H0	FBXW7	P27361	MAPK3	S26	P23S	23	Missense	distal	-3	no	12.241	12.232	EPSD	ICGC;COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q969H0	FBXW7	P27361	MAPK3	T205	L212R	212	Missense	distal	7	no	15.034	14.934	PhosphoSitePlus	ICGC;COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q969H0	FBXW7	P27361	MAPK3	T205	P201T	201	Missense	distal	-4	no	15.034	15.003	PhosphoSitePlus	ICGC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q969H0	FBXW7	P27361	MAPK3	T205	P206T	206	Missense	proximal	1	no	15.034	6.157	PhosphoSitePlus	ICGC	9.358	Loss
CMGC_MAPK_ERK1_MAPK3_ST	Q969H0	FBXW7	P27361	MAPK3	T205	T205K	205	Missense	central	0	yes	15.034	0.000	PhosphoSitePlus	ICGC	9.358	Loss
CMGC_MAPK_ERK1_MAPK3_ST	Q969H0	FBXW7	P27361	MAPK3	T205	V200L	200	Missense	distal	-5	no	15.034	15.050	PhosphoSitePlus	ICGC;COSMIC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q969H0	FBXW7	P27361	MAPK3	T205	G198W	198	Missense	distal	-7	no	15.034	15.325	PhosphoSitePlus	ICGC;COSMIC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q969H0	FBXW7	P27361	MAPK3	S372	G368R	368	Missense	distal	-4	no	15.767	15.728	EPSD	ICGC;COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q969H0	FBXW7	P27361	MAPK3	S372	V375L	375	Missense	distal	3	no	15.767	15.772	EPSD	ICGC;COSMIC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q969H0	FBXW7	P27361	MAPK3	S688	E693K	693	Missense	distal	5	no	9.905	9.777	EPSD	ICGC;COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q969H0	FBXW7	P27361	MAPK3	S688	G687E	687	Missense	proximal	-1	no	9.905	9.946	EPSD	ICGC;COSMIC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P10275	AR	P27361	MAPK3	T18	A22S	22	Missense	distal	4	no	10.192	10.523	EPSD	ICGC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P10275	AR	P27361	MAPK3	T18	P12T	12	Missense	distal	-6	no	10.192	10.108	EPSD	ICGC;COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P10275	AR	P27361	MAPK3	S96	E93K	93	Missense	distal	-3	no	16.503	16.472	EPSD	ICGC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P10275	AR	P27361	MAPK3	S258	G260V	260	Missense	proximal	2	no	15.215	15.206	EPSD	ICGC;COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P10275	AR	P27361	MAPK3	T282	A288T	288	Missense	distal	6	no	14.843	15.214	EPSD	ICGC;COSMIC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P10275	AR	P27361	MAPK3	T282	R280L	280	Missense	proximal	-2	no	14.843	14.859	EPSD	ICGC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P10275	AR	P27361	MAPK3	T282	A288D	288	Missense	distal	6	no	14.843	15.192	EPSD	ICGC;COSMIC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P10275	AR	P27361	MAPK3	S310	T317A	317	Missense	distal	7	no	15.424	15.651	EPSD	ICGC;COSMIC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P10275	AR	P27361	MAPK3	S310	T303S	303	Missense	distal	-7	no	15.424	15.347	EPSD	ICGC;COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P10275	AR	P27361	MAPK3	S310	G314R	314	Missense	distal	4	no	15.424	15.438	EPSD	ICGC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P10275	AR	P27361	MAPK3	S516	Y514H	514	Missense	proximal	-2	no	17.503	17.584	EPSD;PhosphoSitePlus	ICGC;GDSC;CCLE	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P10275	AR	P27361	MAPK3	S516	S516I	516	Missense	central	0	yes	17.503	0.000	EPSD;PhosphoSitePlus	ICGC	9.358	Loss
CMGC_MAPK_ERK1_MAPK3_ST	P10275	AR	P27361	MAPK3	S516	V509L	509	Missense	distal	-7	no	17.503	17.498	EPSD;PhosphoSitePlus	ICGC;COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q15750	TAB1	P27361	MAPK3	S16	P15Q	15	Missense	proximal	-1	no	9.490	9.404	EPSD	ICGC;COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q15750	TAB1	P27361	MAPK3	T376	S373I	373	Missense	distal	-3	no	15.035	14.924	EPSD	ICGC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q15750	TAB1	P27361	MAPK3	T376	P381S	381	Missense	distal	5	no	15.035	15.078	EPSD	ICGC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q15750	TAB1	P27361	MAPK3	T376	S378I	378	Missense	proximal	2	no	15.035	15.000	EPSD	ICGC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q15750	TAB1	P27361	MAPK3	T376	Q374H	374	Missense	proximal	-2	no	15.035	15.571	EPSD	ICGC;COSMIC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q15750	TAB1	P27361	MAPK3	T376	S378R	378	Missense	proximal	2	no	15.035	15.022	EPSD	ICGC;COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q15750	TAB1	P27361	MAPK3	T376	Q374K	374	Missense	proximal	-2	no	15.035	14.458	EPSD	ICGC;COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q15750	TAB1	P27361	MAPK3	S378	S373I	373	Missense	distal	-5	no	16.242	16.147	EPSD	ICGC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q15750	TAB1	P27361	MAPK3	S378	P381S	381	Missense	distal	3	no	16.242	16.237	EPSD	ICGC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q15750	TAB1	P27361	MAPK3	S378	S378I	378	Missense	central	0	yes	16.242	0.000	EPSD	ICGC	9.358	Loss
CMGC_MAPK_ERK1_MAPK3_ST	Q15750	TAB1	P27361	MAPK3	S378	Q374H	374	Missense	distal	-4	no	16.242	16.246	EPSD	ICGC;COSMIC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q15750	TAB1	P27361	MAPK3	S378	S378R	378	Missense	central	0	yes	16.242	0.000	EPSD	ICGC;COSMIC	9.358	Loss
CMGC_MAPK_ERK1_MAPK3_ST	Q15750	TAB1	P27361	MAPK3	S378	Q374K	374	Missense	distal	-4	no	16.242	16.224	EPSD	ICGC;COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q15750	TAB1	P27361	MAPK3	T431	L434I	434	Missense	distal	3	no	13.827	13.808	EPSD	ICGC;COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q15750	TAB1	P27361	MAPK3	T431	S438R	438	Missense	distal	7	no	13.827	13.997	EPSD	ICGC;COSMIC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q15750	TAB1	P27361	MAPK3	S438	L434I	434	Missense	distal	-4	no	16.253	16.234	PhosphoSitePlus	ICGC;COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q15750	TAB1	P27361	MAPK3	S438	S438R	438	Missense	central	0	yes	16.253	0.000	PhosphoSitePlus	ICGC;COSMIC	9.358	Loss
CMGC_MAPK_ERK1_MAPK3_ST	Q15750	TAB1	P27361	MAPK3	S492	Y488S	488	Missense	distal	-4	no	10.093	10.196	EPSD	ICGC;COSMIC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q15750	TAB1	P27361	MAPK3	S492	E486D	486	Missense	distal	-6	no	10.093	10.049	EPSD	ICGC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q15750	TAB1	P27361	MAPK3	S492	R489S	489	Missense	distal	-3	no	10.093	10.130	EPSD	ICGC;COSMIC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P35228	NOS2	P27361	MAPK3	S56	L49F	49	Missense	distal	-7	no	14.780	14.855	EPSD	ICGC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P35228	NOS2	P27361	MAPK3	S124	K123E	123	Missense	proximal	-1	no	9.561	9.591	EPSD	ICGC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P35228	NOS2	P27361	MAPK3	S124	S118F	118	Missense	distal	-6	no	9.561	9.094	EPSD	ICGC;COSMIC	9.358	Loss
CMGC_MAPK_ERK1_MAPK3_ST	P35228	NOS2	P27361	MAPK3	S124	S124N	124	Missense	central	0	yes	9.561	0.000	EPSD	ICGC;COSMIC;GDSC	9.358	Loss
CMGC_MAPK_ERK1_MAPK3_ST	P35228	NOS2	P27361	MAPK3	S745	P746L	746	Missense	proximal	1	no	15.298	6.260	PhosphoSitePlus	ICGC;COSMIC	9.358	Loss
CMGC_MAPK_ERK1_MAPK3_ST	P35228	NOS2	P27361	MAPK3	S745	T747K	747	Missense	proximal	2	no	15.298	15.293	PhosphoSitePlus	ICGC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P35228	NOS2	P27361	MAPK3	S745	Q741K	741	Missense	distal	-4	no	15.298	15.281	PhosphoSitePlus	ICGC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P35228	NOS2	P27361	MAPK3	S745	R750H	750	Missense	distal	5	no	15.298	15.334	PhosphoSitePlus	ICGC;COSMIC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P35228	NOS2	P27361	MAPK3	S745	S748F	748	Missense	distal	3	no	15.298	15.233	PhosphoSitePlus	ICGC;COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P35228	NOS2	P27361	MAPK3	S898	Q899R	899	Missense	proximal	1	no	9.855	8.298	EPSD	ICGC;COSMIC	9.358	Loss
CMGC_MAPK_ERK1_MAPK3_ST	P35228	NOS2	P27361	MAPK3	S898	Q899H	899	Missense	proximal	1	no	9.855	10.043	EPSD	ICGC;COSMIC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P35228	NOS2	P27361	MAPK3	S898	Q899L	899	Missense	proximal	1	no	9.855	8.761	EPSD	ICGC;COSMIC	9.358	Loss
CMGC_MAPK_ERK1_MAPK3_ST	P13631	RARG	P27361	MAPK3	S36	S43R	43	Missense	distal	7	no	16.532	16.701	EPSD	ICGC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P13631	RARG	P27361	MAPK3	S36	A32E	32	Missense	distal	-4	no	16.532	16.639	EPSD	ICGC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P13631	RARG	P27361	MAPK3	S36	L42P	42	Missense	distal	6	no	16.532	16.759	EPSD	ICGC;COSMIC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P13631	RARG	P27361	MAPK3	S43	S43R	43	Missense	central	0	yes	14.622	0.000	EPSD	ICGC	9.358	Loss
CMGC_MAPK_ERK1_MAPK3_ST	P13631	RARG	P27361	MAPK3	S43	P44T	44	Missense	proximal	1	no	14.622	5.745	EPSD	ICGC	9.358	Loss
CMGC_MAPK_ERK1_MAPK3_ST	P13631	RARG	P27361	MAPK3	S43	L42P	42	Missense	proximal	-1	no	14.622	14.717	EPSD	ICGC;COSMIC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P13631	RARG	P27361	MAPK3	S176	P177L	177	Missense	proximal	1	no	16.552	7.514	EPSD	ICGC;COSMIC	9.358	Loss
CMGC_MAPK_ERK1_MAPK3_ST	P13631	RARG	P27361	MAPK3	S179	P177L	177	Missense	proximal	-2	no	13.070	11.686	EPSD	ICGC;COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P13631	RARG	P27361	MAPK3	S426	P431H	431	Missense	distal	5	no	9.686	9.621	EPSD	ICGC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P13631	RARG	P27361	MAPK3	S426	P431S	431	Missense	distal	5	no	9.686	9.729	EPSD	ICGC;COSMIC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P13631	RARG	P27361	MAPK3	S427	P431H	431	Missense	distal	4	no	10.051	9.960	EPSD	ICGC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P13631	RARG	P27361	MAPK3	S427	P431S	431	Missense	distal	4	no	10.051	10.100	EPSD	ICGC;COSMIC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P13631	RARG	P27361	MAPK3	S436	P431H	431	Missense	distal	-5	no	10.454	10.423	EPSD	ICGC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P13631	RARG	P27361	MAPK3	S436	P431S	431	Missense	distal	-5	no	10.454	10.459	EPSD	ICGC;COSMIC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P13631	RARG	P27361	MAPK3	S437	P431S	431	Missense	distal	-6	no	9.340	9.424	EPSD	ICGC;COSMIC	9.358	Gain
CMGC_MAPK_ERK1_MAPK3_ST	P33981	TTK	P27361	MAPK3	S80	D81Y	81	Missense	proximal	1	no	8.485	10.038	EPSD	ICGC	9.358	Gain
CMGC_MAPK_ERK1_MAPK3_ST	P33981	TTK	P27361	MAPK3	S214	A211S	211	Missense	distal	-3	no	10.029	10.120	EPSD	ICGC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P33981	TTK	P27361	MAPK3	S214	A211D	211	Missense	distal	-3	no	10.029	10.098	EPSD	ICGC;COSMIC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P33981	TTK	P27361	MAPK3	S258	L259F	259	Missense	proximal	1	no	6.909	9.733	EPSD	ICGC;COSMIC	9.358	Gain
CMGC_MAPK_ERK1_MAPK3_ST	P33981	TTK	P27361	MAPK3	S281	D283N	283	Missense	proximal	2	no	17.437	17.431	EPSD	ICGC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P33981	TTK	P27361	MAPK3	S582	I585V	585	Missense	distal	3	no	9.807	9.821	EPSD	ICGC;COSMIC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P33981	TTK	P27361	MAPK3	S582	I585T	585	Missense	distal	3	no	9.807	9.845	EPSD	ICGC;COSMIC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P33981	TTK	P27361	MAPK3	S837	G838S	838	Missense	proximal	1	no	8.081	10.567	EPSD	ICGC;COSMIC	9.358	Gain
CMGC_MAPK_ERK1_MAPK3_ST	P33981	TTK	P27361	MAPK3	S844	G838S	838	Missense	distal	-6	no	10.791	10.853	EPSD	ICGC;COSMIC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q86UR1	NOXA1	P27361	MAPK3	S282	P283Q	283	Missense	proximal	1	no	16.898	8.954	PhosphoSitePlus	ICGC;COSMIC	9.358	Loss
CMGC_MAPK_ERK1_MAPK3_ST	Q86UR1	NOXA1	P27361	MAPK3	S409	P415S	415	Missense	distal	6	no	10.299	10.429	EPSD	ICGC;COSMIC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q86UR1	NOXA1	P27361	MAPK3	S409	P415L	415	Missense	distal	6	no	10.299	10.073	EPSD	ICGC;COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	O60331	PIP5K1C	P27361	MAPK3	S453	S449Y	449	Missense	distal	-4	no	13.524	13.421	EPSD	ICGC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	O60331	PIP5K1C	P27361	MAPK3	S453	G458W	458	Missense	distal	5	no	13.524	12.977	EPSD	ICGC;COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	O60331	PIP5K1C	P27361	MAPK3	S453	S455P	455	Missense	proximal	2	no	13.524	13.522	EPSD	ICGC;COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	O60331	PIP5K1C	P27361	MAPK3	S539	P536H	536	Missense	distal	-3	no	16.757	16.717	EPSD	ICGC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	O60331	PIP5K1C	P27361	MAPK3	S539	S544L	544	Missense	distal	5	no	16.757	16.486	EPSD	ICGC;COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	O60331	PIP5K1C	P27361	MAPK3	T553	T553A	553	Missense	central	0	yes	10.824	0.000	EPSD	ICGC	9.358	Loss
CMGC_MAPK_ERK1_MAPK3_ST	O60331	PIP5K1C	P27361	MAPK3	S650	W647L	647	Missense	distal	-3	no	18.963	19.093	PhosphoSitePlus	ICGC;COSMIC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	O60331	PIP5K1C	P27361	MAPK3	S650	R645M	645	Missense	distal	-5	no	18.963	18.890	PhosphoSitePlus	ICGC;COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	O60331	PIP5K1C	P27361	MAPK3	S650	R645G	645	Missense	distal	-5	no	18.963	18.965	PhosphoSitePlus	ICGC;COSMIC;CCLE	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	O60331	PIP5K1C	P27361	MAPK3	S655	A658V	658	Missense	distal	3	no	9.580	9.586	EPSD	ICGC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	O60331	PIP5K1C	P27361	MAPK3	S662	A658V	658	Missense	distal	-4	no	12.268	12.248	EPSD	ICGC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P27824	CANX	P27361	MAPK3	S55	A51S	51	Missense	distal	-4	no	18.319	18.451	EPSD	ICGC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P27824	CANX	P27361	MAPK3	S564	E567K	567	Missense	distal	3	no	11.048	11.038	EPSD	ICGC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P27824	CANX	P27361	MAPK3	S583	K588R	588	Missense	distal	5	no	18.094	18.102	PhosphoSitePlus	ICGC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q12931	TRAP1	P27361	MAPK3	S472	R469H	469	Missense	distal	-3	no	9.483	9.489	EPSD	ICGC;COSMIC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q12931	TRAP1	P27361	MAPK3	S472	A465S	465	Missense	distal	-7	no	9.483	9.333	EPSD	ICGC;COSMIC	9.358	Loss
CMGC_MAPK_ERK1_MAPK3_ST	Q12931	TRAP1	P27361	MAPK3	S511	K518T	518	Missense	distal	7	no	13.698	13.642	PhosphoSitePlus	ICGC;COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q92908	GATA6	P27361	MAPK3	T34	P38T	38	Missense	distal	4	no	17.386	17.322	EPSD	ICGC;COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q92908	GATA6	P27361	MAPK3	T34	P38H	38	Missense	distal	4	no	17.386	17.294	EPSD	ICGC;COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q92908	GATA6	P27361	MAPK3	S37	P38T	38	Missense	proximal	1	no	19.186	10.309	EPSD	ICGC;COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q92908	GATA6	P27361	MAPK3	S37	P38H	38	Missense	proximal	1	no	19.186	11.431	EPSD	ICGC;COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q92908	GATA6	P27361	MAPK3	S44	S45C	45	Missense	proximal	1	no	9.510	3.255	EPSD	ICGC;COSMIC	9.358	Loss
CMGC_MAPK_ERK1_MAPK3_ST	Q92908	GATA6	P27361	MAPK3	S44	P38T	38	Missense	distal	-6	no	9.510	9.426	EPSD	ICGC;COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q92908	GATA6	P27361	MAPK3	S44	P38H	38	Missense	distal	-6	no	9.510	9.430	EPSD	ICGC;COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q92908	GATA6	P27361	MAPK3	T62	A57T	57	Missense	distal	-5	no	10.474	10.557	EPSD	ICGC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q92908	GATA6	P27361	MAPK3	S266	A261E	261	Missense	distal	-5	no	17.296	17.360	PhosphoSitePlus	ICGC;COSMIC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q92908	GATA6	P27361	MAPK3	S266	A261V	261	Missense	distal	-5	no	17.296	17.319	PhosphoSitePlus	ICGC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q92908	GATA6	P27361	MAPK3	S266	A272S	272	Missense	distal	6	no	17.296	17.821	PhosphoSitePlus	ICGC;COSMIC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q92908	GATA6	P27361	MAPK3	S268	A261E	261	Missense	distal	-7	no	15.345	15.228	EPSD	ICGC;COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q92908	GATA6	P27361	MAPK3	S268	A261V	261	Missense	distal	-7	no	15.345	15.344	EPSD	ICGC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q92908	GATA6	P27361	MAPK3	S268	A272S	272	Missense	distal	4	no	15.345	15.676	EPSD	ICGC;COSMIC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q92908	GATA6	P27361	MAPK3	T515	I512T	512	Missense	distal	-3	no	18.227	18.309	EPSD	ICGC;COSMIC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q92908	GATA6	P27361	MAPK3	T515	M514I	514	Missense	proximal	-1	no	18.227	18.251	EPSD	ICGC;COSMIC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q92908	GATA6	P27361	MAPK3	T515	T517A	517	Missense	proximal	2	no	18.227	18.200	EPSD	ICGC;COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q92908	GATA6	P27361	MAPK3	S531	D525N	525	Missense	distal	-6	no	17.038	16.976	EPSD	ICGC;COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q92908	GATA6	P27361	MAPK3	T534	A541S	541	Missense	distal	7	no	9.798	9.452	EPSD	ICGC;COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q86UC2	RSPH3	P27361	MAPK3	T286	T286K	286	Missense	central	0	yes	16.241	0.000	PhosphoSitePlus	ICGC	9.358	Loss
CMGC_MAPK_ERK1_MAPK3_ST	Q9UQC2	GAB2	P27361	MAPK3	T319	P320S	320	Missense	proximal	1	no	16.047	6.993	EPSD	ICGC;COSMIC	9.358	Loss
CMGC_MAPK_ERK1_MAPK3_ST	P10828	THRB	P27361	MAPK3	T2	T2P	2	Missense	central	0	yes	12.355	0.000	EPSD	ICGC;COSMIC	9.358	Loss
CMGC_MAPK_ERK1_MAPK3_ST	P10828	THRB	P27361	MAPK3	S55	Q53K	53	Missense	proximal	-2	no	16.674	16.097	EPSD	ICGC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P10828	THRB	P27361	MAPK3	S55	H57N	57	Missense	proximal	2	no	16.674	16.672	EPSD	ICGC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P10828	THRB	P27361	MAPK3	S55	T48K	48	Missense	distal	-7	no	16.674	16.681	EPSD	ICGC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P10828	THRB	P27361	MAPK3	S55	T61N	61	Missense	distal	6	no	16.674	16.600	EPSD	ICGC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P10828	THRB	P27361	MAPK3	S55	E52K	52	Missense	distal	-3	no	16.674	16.643	EPSD	ICGC;COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P10828	THRB	P27361	MAPK3	S55	T48M	48	Missense	distal	-7	no	16.674	16.802	EPSD	ICGC;COSMIC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P10828	THRB	P27361	MAPK3	S142	P141A	141	Missense	proximal	-1	no	10.118	9.978	PhosphoSitePlus	ICGC;COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P10828	THRB	P27361	MAPK3	S142	Y143C	143	Missense	proximal	1	no	10.118	1.858	PhosphoSitePlus	ICGC;COSMIC	9.358	Loss
CMGC_MAPK_ERK1_MAPK3_ST	P10301	RRAS	P27361	MAPK3	S201	A205D	205	Missense	distal	4	no	20.640	20.852	PhosphoSitePlus	ICGC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P10301	RRAS	P27361	MAPK3	S201	Q196K	196	Missense	distal	-5	no	20.640	20.647	PhosphoSitePlus	ICGC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P10301	RRAS	P27361	MAPK3	S201	E197K	197	Missense	distal	-4	no	20.640	20.581	PhosphoSitePlus	ICGC;COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P10301	RRAS	P27361	MAPK3	S204	G211R	211	Missense	distal	7	no	11.768	11.798	EPSD	ICGC;COSMIC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P10301	RRAS	P27361	MAPK3	S204	A205D	205	Missense	proximal	1	no	11.768	12.407	EPSD	ICGC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P10301	RRAS	P27361	MAPK3	S204	E197K	197	Missense	distal	-7	no	11.768	11.820	EPSD	ICGC;COSMIC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q92797	SYMPK	P27361	MAPK3	S16	R11S	11	Missense	distal	-5	no	10.950	10.996	EPSD	ICGC;COSMIC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q92797	SYMPK	P27361	MAPK3	S510	A516E	516	Missense	distal	6	no	16.225	16.619	EPSD	ICGC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q92797	SYMPK	P27361	MAPK3	S870	P871S	871	Missense	proximal	1	no	18.666	9.613	EPSD	ICGC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q92797	SYMPK	P27361	MAPK3	S1081	R1080C	1080	Missense	proximal	-1	no	9.423	9.238	EPSD	ICGC;COSMIC	9.358	Loss
CMGC_MAPK_ERK1_MAPK3_ST	Q92797	SYMPK	P27361	MAPK3	S1081	L1076M	1076	Missense	distal	-5	no	9.423	9.365	EPSD	ICGC;COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q92797	SYMPK	P27361	MAPK3	T1083	R1080C	1080	Missense	distal	-3	no	16.399	16.259	EPSD	ICGC;COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q92797	SYMPK	P27361	MAPK3	T1083	L1076M	1076	Missense	distal	-7	no	16.399	16.459	EPSD	ICGC;COSMIC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q92797	SYMPK	P27361	MAPK3	S1168	A1166D	1166	Missense	proximal	-2	no	8.879	9.623	EPSD	ICGC	9.358	Gain
CMGC_MAPK_ERK1_MAPK3_ST	Q92797	SYMPK	P27361	MAPK3	S1169	A1166D	1166	Missense	distal	-3	no	10.433	10.502	EPSD	ICGC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q92797	SYMPK	P27361	MAPK3	S1171	A1166D	1166	Missense	distal	-5	no	17.186	17.250	EPSD	ICGC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q92797	SYMPK	P27361	MAPK3	S1173	A1166D	1166	Missense	distal	-7	no	18.292	18.184	EPSD	ICGC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q92797	SYMPK	P27361	MAPK3	S1243	S1243R	1243	Missense	central	0	yes	17.169	0.000	EPSD	ICGC	9.358	Loss
CMGC_MAPK_ERK1_MAPK3_ST	Q92797	SYMPK	P27361	MAPK3	T1246	S1243R	1243	Missense	distal	-3	no	9.525	9.487	EPSD	ICGC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q9NRF2	SH2B1	P27361	MAPK3	S25	R27W	27	Missense	proximal	2	no	13.831	13.771	EPSD	ICGC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q9NRF2	SH2B1	P27361	MAPK3	S25	P22L	22	Missense	distal	-3	no	13.831	13.747	EPSD	ICGC;COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q9NRF2	SH2B1	P27361	MAPK3	S88	S88L	88	Missense	central	0	yes	17.328	0.000	EPSD	ICGC	9.358	Loss
CMGC_MAPK_ERK1_MAPK3_ST	Q9NRF2	SH2B1	P27361	MAPK3	S88	P89A	89	Missense	proximal	1	no	17.328	8.088	EPSD	ICGC;COSMIC	9.358	Loss
CMGC_MAPK_ERK1_MAPK3_ST	Q9NRF2	SH2B1	P27361	MAPK3	S88	R82L	82	Missense	distal	-6	no	17.328	17.157	EPSD	ICGC;COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q9NRF2	SH2B1	P27361	MAPK3	S96	P89A	89	Missense	distal	-7	no	16.625	16.737	PhosphoSitePlus	ICGC;COSMIC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q9NRF2	SH2B1	P27361	MAPK3	S96	A99G	99	Missense	distal	3	no	16.625	16.654	PhosphoSitePlus	ICGC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q9NRF2	SH2B1	P27361	MAPK3	S102	A99G	99	Missense	distal	-3	no	16.228	16.287	EPSD	ICGC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q9NRF2	SH2B1	P27361	MAPK3	S144	L149I	149	Missense	distal	5	no	9.509	9.387	EPSD	ICGC;COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q9NRF2	SH2B1	P27361	MAPK3	S219	S215G	215	Missense	distal	-4	no	15.125	15.087	EPSD	ICGC;COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q9NRF2	SH2B1	P27361	MAPK3	S376	A382S	382	Missense	distal	6	no	11.443	11.968	EPSD	ICGC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q9NRF2	SH2B1	P27361	MAPK3	S384	A382S	382	Missense	proximal	-2	no	13.920	15.194	EPSD	ICGC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P53355	DAPK1	P27361	MAPK3	T180	E187K	187	Missense	distal	7	no	11.848	11.919	EPSD	ICGC;COSMIC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P53355	DAPK1	P27361	MAPK3	T180	F183C	183	Missense	distal	3	no	11.848	11.827	EPSD	ICGC;COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P53355	DAPK1	P27361	MAPK3	S321	S321L	321	Missense	central	0	yes	9.981	0.000	EPSD	ICGC;COSMIC	9.358	Loss
CMGC_MAPK_ERK1_MAPK3_ST	P53355	DAPK1	P27361	MAPK3	S321	R317G	317	Missense	distal	-4	no	9.981	10.019	EPSD	ICGC;COSMIC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P53355	DAPK1	P27361	MAPK3	S342	S342F	342	Missense	central	0	yes	11.902	0.000	EPSD	ICGC;COSMIC	9.358	Loss
CMGC_MAPK_ERK1_MAPK3_ST	P53355	DAPK1	P27361	MAPK3	S342	V344L	344	Missense	proximal	2	no	11.902	11.904	EPSD	ICGC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P53355	DAPK1	P27361	MAPK3	S342	I348V	348	Missense	distal	6	no	11.902	12.033	EPSD	ICGC;COSMIC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P53355	DAPK1	P27361	MAPK3	S342	K346N	346	Missense	distal	4	no	11.902	11.894	EPSD	ICGC;COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P53355	DAPK1	P27361	MAPK3	S342	D338N	338	Missense	distal	-4	no	11.902	11.876	EPSD	ICGC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P53355	DAPK1	P27361	MAPK3	S342	A347V	347	Missense	distal	5	no	11.902	11.891	EPSD	ICGC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P53355	DAPK1	P27361	MAPK3	T612	L616P	616	Missense	distal	4	no	13.278	13.432	EPSD	ICGC;COSMIC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P53355	DAPK1	P27361	MAPK3	T612	N619Y	619	Missense	distal	7	no	13.278	13.367	EPSD	ICGC;COSMIC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P53355	DAPK1	P27361	MAPK3	T612	R611L	611	Missense	proximal	-1	no	13.278	13.230	EPSD	ICGC;COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P53355	DAPK1	P27361	MAPK3	T612	T612M	612	Missense	central	0	yes	13.278	0.000	EPSD	ICGC;COSMIC	9.358	Loss
CMGC_MAPK_ERK1_MAPK3_ST	P53355	DAPK1	P27361	MAPK3	S734	L736M	736	Missense	proximal	2	no	20.876	20.856	PhosphoSitePlus	ICGC;COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P53355	DAPK1	P27361	MAPK3	S734	S738F	738	Missense	distal	4	no	20.876	20.462	PhosphoSitePlus	ICGC;GDSC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P53355	DAPK1	P27361	MAPK3	S909	L910F	910	Missense	proximal	1	no	7.391	10.216	EPSD	ICGC	9.358	Gain
CMGC_MAPK_ERK1_MAPK3_ST	P53355	DAPK1	P27361	MAPK3	T1053	R1055L	1055	Missense	proximal	2	no	14.530	14.519	EPSD	ICGC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P53355	DAPK1	P27361	MAPK3	T1053	G1046W	1046	Missense	distal	-7	no	14.530	14.821	EPSD	ICGC;COSMIC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P53355	DAPK1	P27361	MAPK3	T1053	R1055Q	1055	Missense	proximal	2	no	14.530	14.521	EPSD	ICGC;COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P53355	DAPK1	P27361	MAPK3	S1115	R1114C	1114	Missense	proximal	-1	no	10.334	10.149	EPSD	ICGC;COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P53355	DAPK1	P27361	MAPK3	S1115	D1110N	1110	Missense	distal	-5	no	10.334	10.328	EPSD	ICGC;COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P53355	DAPK1	P27361	MAPK3	S1115	E1122K	1122	Missense	distal	7	no	10.334	10.405	EPSD	ICGC;COSMIC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P53355	DAPK1	P27361	MAPK3	S1115	A1117D	1117	Missense	proximal	2	no	10.334	10.361	EPSD	ICGC;COSMIC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P53355	DAPK1	P27361	MAPK3	S1115	W1116C	1116	Missense	proximal	1	no	10.334	2.930	EPSD	ICGC;COSMIC	9.358	Loss
CMGC_MAPK_ERK1_MAPK3_ST	P53355	DAPK1	P27361	MAPK3	S1115	A1117T	1117	Missense	proximal	2	no	10.334	10.361	EPSD	ICGC;COSMIC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P53355	DAPK1	P27361	MAPK3	S1425	G1418S	1418	Missense	distal	-7	no	9.567	9.529	EPSD	ICGC;COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P53355	DAPK1	P27361	MAPK3	S1425	G1418C	1418	Missense	distal	-7	no	9.567	9.798	EPSD	ICGC;COSMIC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q16254	E2F4	P27361	MAPK3	T14	S21I	21	Missense	distal	7	no	17.274	17.673	EPSD	ICGC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q16254	E2F4	P27361	MAPK3	T14	R17W	17	Missense	distal	3	no	17.274	17.196	EPSD	ICGC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q16254	E2F4	P27361	MAPK3	S16	R17W	17	Missense	proximal	1	no	8.784	10.381	EPSD	ICGC	9.358	Gain
CMGC_MAPK_ERK1_MAPK3_ST	Q16254	E2F4	P27361	MAPK3	S21	S21I	21	Missense	central	0	yes	9.905	0.000	EPSD	ICGC	9.358	Loss
CMGC_MAPK_ERK1_MAPK3_ST	Q16254	E2F4	P27361	MAPK3	S21	R17W	17	Missense	distal	-4	no	9.905	9.698	EPSD	ICGC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q16254	E2F4	P27361	MAPK3	S21	K28R	28	Missense	distal	7	no	9.905	9.900	EPSD	ICGC;COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q16254	E2F4	P27361	MAPK3	S202	P208S	208	Missense	distal	6	no	13.160	13.290	EPSD	ICGC;COSMIC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q16254	E2F4	P27361	MAPK3	S202	V205E	205	Missense	distal	3	no	13.160	13.184	EPSD	ICGC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q16254	E2F4	P27361	MAPK3	S218	D214Y	214	Missense	distal	-4	no	16.771	16.703	EPSD	ICGC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q16254	E2F4	P27361	MAPK3	T224	P231S	231	Missense	distal	7	no	16.649	16.572	EPSD	ICGC;COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q16254	E2F4	P27361	MAPK3	T224	P226L	226	Missense	proximal	2	no	16.649	16.628	EPSD	ICGC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q16254	E2F4	P27361	MAPK3	T224	P229H	229	Missense	distal	5	no	16.649	16.584	EPSD	ICGC;COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q16254	E2F4	P27361	MAPK3	S244	R241S	241	Missense	distal	-3	no	16.884	16.922	EPSD;PhosphoSitePlus	ICGC;COSMIC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q16254	E2F4	P27361	MAPK3	S244	R241L	241	Missense	distal	-3	no	16.884	16.846	EPSD;PhosphoSitePlus	ICGC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q16254	E2F4	P27361	MAPK3	S244	E238K	238	Missense	distal	-6	no	16.884	16.742	EPSD;PhosphoSitePlus	ICGC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q16254	E2F4	P27361	MAPK3	T248	R241S	241	Missense	distal	-7	no	12.642	12.559	EPSD	ICGC;COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q16254	E2F4	P27361	MAPK3	T248	R241L	241	Missense	distal	-7	no	12.642	12.704	EPSD	ICGC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q16254	E2F4	P27361	MAPK3	S384	R382P	382	Missense	proximal	-2	no	17.924	19.324	PhosphoSitePlus;EPSD	ICGC;COSMIC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q16254	E2F4	P27361	MAPK3	S384	D391Y	391	Missense	distal	7	no	17.924	18.072	PhosphoSitePlus;EPSD	ICGC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q16254	E2F4	P27361	MAPK3	S399	C403S	403	Missense	distal	4	no	9.003	9.506	EPSD	ICGC;COSMIC	9.358	Gain
CMGC_MAPK_ERK1_MAPK3_ST	Q8NET8	TRPV3	P27361	MAPK3	T35	P31L	31	Missense	distal	-4	no	13.858	13.745	EPSD	ICGC;COSMIC;GDSC;CCLE	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q8NET8	TRPV3	P27361	MAPK3	T35	P36L	36	Missense	proximal	1	no	13.858	4.820	EPSD	ICGC;COSMIC	9.358	Loss
CMGC_MAPK_ERK1_MAPK3_ST	Q8NET8	TRPV3	P27361	MAPK3	T35	P31R	31	Missense	distal	-4	no	13.858	13.808	EPSD	ICGC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q8NET8	TRPV3	P27361	MAPK3	T264	G262C	262	Missense	proximal	-2	no	13.493	12.094	PhosphoSitePlus	ICGC;COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q8NET8	TRPV3	P27361	MAPK3	T264	A270T	270	Missense	distal	6	no	13.493	13.864	PhosphoSitePlus	ICGC;COSMIC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P41182	BCL6	P27361	MAPK3	S3	D6E	6	Missense	distal	3	no	12.756	12.754	EPSD	ICGC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P41182	BCL6	P27361	MAPK3	S243	S250F	250	Missense	distal	7	no	8.878	9.369	EPSD	ICGC	9.358	Gain
CMGC_MAPK_ERK1_MAPK3_ST	P41182	BCL6	P27361	MAPK3	S250	H255Q	255	Missense	distal	5	no	16.503	16.465	EPSD	ICGC;COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P41182	BCL6	P27361	MAPK3	S250	S250F	250	Missense	central	0	yes	16.503	0.000	EPSD	ICGC	9.358	Loss
CMGC_MAPK_ERK1_MAPK3_ST	P41182	BCL6	P27361	MAPK3	S260	H255Q	255	Missense	distal	-5	no	15.759	15.743	EPSD	ICGC;COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P41182	BCL6	P27361	MAPK3	S260	T264K	264	Missense	distal	4	no	15.759	15.734	EPSD	ICGC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P41182	BCL6	P27361	MAPK3	S330	R325W	325	Missense	distal	-5	no	15.960	15.806	EPSD	ICGC;COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P41182	BCL6	P27361	MAPK3	S330	Q332K	332	Missense	proximal	2	no	15.960	15.966	EPSD	ICGC;COSMIC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P41182	BCL6	P27361	MAPK3	S333	Q332K	332	Missense	proximal	-1	no	17.639	17.665	PhosphoSitePlus;EPSD	ICGC;COSMIC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P41182	BCL6	P27361	MAPK3	S333	D338E	338	Missense	distal	5	no	17.639	17.658	PhosphoSitePlus;EPSD	ICGC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P41182	BCL6	P27361	MAPK3	S366	A372T	372	Missense	distal	6	no	15.222	15.593	EPSD	ICGC;COSMIC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P41182	BCL6	P27361	MAPK3	S427	E421K	421	Missense	distal	-6	no	16.223	16.082	EPSD	ICGC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P41182	BCL6	P27361	MAPK3	S457	M454I	454	Missense	distal	-3	no	16.788	16.804	EPSD	ICGC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P41182	BCL6	P27361	MAPK3	S457	P458H	458	Missense	proximal	1	no	16.788	9.032	EPSD	ICGC	9.358	Loss
CMGC_MAPK_ERK1_MAPK3_ST	P41182	BCL6	P27361	MAPK3	S457	R459C	459	Missense	proximal	2	no	16.788	16.739	EPSD	ICGC;COSMIC;GDSC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P41182	BCL6	P27361	MAPK3	S460	M454I	454	Missense	distal	-6	no	9.365	9.389	EPSD	ICGC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P41182	BCL6	P27361	MAPK3	S460	P458H	458	Missense	proximal	-2	no	9.365	8.138	EPSD	ICGC	9.358	Loss
CMGC_MAPK_ERK1_MAPK3_ST	P41182	BCL6	P27361	MAPK3	S460	R459C	459	Missense	proximal	-1	no	9.365	9.180	EPSD	ICGC;COSMIC;GDSC	9.358	Loss
CMGC_MAPK_ERK1_MAPK3_ST	P41182	BCL6	P27361	MAPK3	S466	R459C	459	Missense	distal	-7	no	16.090	16.277	EPSD	ICGC;COSMIC;GDSC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P41182	BCL6	P27361	MAPK3	S466	P473L	473	Missense	distal	7	no	16.090	16.283	EPSD	ICGC;COSMIC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q13164	MAPK7	P27361	MAPK3	T209	S210P	210	Missense	proximal	1	no	5.263	14.316	EPSD	ICGC	9.358	Gain
CMGC_MAPK_ERK1_MAPK3_ST	Q13164	MAPK7	P27361	MAPK3	S210	S210P	210	Missense	central	0	yes	12.253	0.000	EPSD	ICGC	9.358	Loss
CMGC_MAPK_ERK1_MAPK3_ST	Q13164	MAPK7	P27361	MAPK3	S210	A212T	212	Missense	proximal	2	no	12.253	12.280	EPSD	ICGC;COSMIC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q13164	MAPK7	P27361	MAPK3	T594	P589S	589	Missense	distal	-5	no	13.741	13.746	EPSD	ICGC;COSMIC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q13164	MAPK7	P27361	MAPK3	T594	P595S	595	Missense	proximal	1	no	13.741	4.688	EPSD	ICGC;COSMIC	9.358	Loss
CMGC_MAPK_ERK1_MAPK3_ST	Q13164	MAPK7	P27361	MAPK3	S720	D724Y	724	Missense	distal	4	no	9.594	9.497	EPSD	ICGC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q13164	MAPK7	P27361	MAPK3	S720	Q721L	721	Missense	proximal	1	no	9.594	8.500	EPSD	ICGC;COSMIC	9.358	Loss
CMGC_MAPK_ERK1_MAPK3_ST	Q13164	MAPK7	P27361	MAPK3	S720	L717I	717	Missense	distal	-3	no	9.594	9.558	EPSD	ICGC;COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q13164	MAPK7	P27361	MAPK3	T733	A739S	739	Missense	distal	6	no	14.651	15.177	PhosphoSitePlus	ICGC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q13164	MAPK7	P27361	MAPK3	S803	S803Y	803	Missense	central	0	yes	17.284	0.000	EPSD	ICGC;COSMIC	9.358	Loss
CMGC_MAPK_ERK1_MAPK3_ST	Q9H9Z2	LIN28A	P27361	MAPK3	T189	P182L	182	Missense	distal	-7	no	12.129	12.236	EPSD	ICGC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q9H9Z2	LIN28A	P27361	MAPK3	T189	F191Y	191	Missense	proximal	2	no	12.129	12.157	EPSD	ICGC;COSMIC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q9H9Z2	LIN28A	P27361	MAPK3	T189	P182H	182	Missense	distal	-7	no	12.129	12.163	EPSD	ICGC;COSMIC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q9H9Z2	LIN28A	P27361	MAPK3	S200	H199N	199	Missense	proximal	-1	no	18.673	18.663	PhosphoSitePlus	ICGC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q9H9Z2	LIN28A	P27361	MAPK3	T202	H199N	199	Missense	distal	-3	no	10.015	10.002	EPSD	ICGC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q12772	SREBF2	P27361	MAPK3	S79	R77S	77	Missense	proximal	-2	no	9.393	9.717	EPSD	ICGC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q12772	SREBF2	P27361	MAPK3	S101	S103L	103	Missense	proximal	2	no	16.091	16.067	EPSD	ICGC;COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q12772	SREBF2	P27361	MAPK3	S106	S103L	103	Missense	distal	-3	no	14.132	14.057	EPSD	ICGC;COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q12772	SREBF2	P27361	MAPK3	T124	L131I	131	Missense	distal	7	no	16.527	16.656	EPSD	ICGC;COSMIC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q12772	SREBF2	P27361	MAPK3	T128	L131I	131	Missense	distal	3	no	13.838	13.819	EPSD	ICGC;COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q12772	SREBF2	P27361	MAPK3	S432	S438P	438	Missense	distal	6	no	16.998	16.868	EPSD;PhosphoSitePlus	ICGC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q12772	SREBF2	P27361	MAPK3	S455	G454R	454	Missense	proximal	-1	no	19.584	19.608	PhosphoSitePlus;EPSD	ICGC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q12772	SREBF2	P27361	MAPK3	S469	P471L	471	Missense	proximal	2	no	18.967	18.945	EPSD	ICGC;COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q12772	SREBF2	P27361	MAPK3	S469	V472L	472	Missense	distal	3	no	18.967	18.972	EPSD	ICGC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q12772	SREBF2	P27361	MAPK3	S846	S846C	846	Missense	central	0	yes	10.548	0.000	EPSD	ICGC;COSMIC	9.358	Loss
CMGC_MAPK_ERK1_MAPK3_ST	Q12772	SREBF2	P27361	MAPK3	S846	D849N	849	Missense	distal	3	no	10.548	10.538	EPSD	ICGC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q12772	SREBF2	P27361	MAPK3	S846	V851M	851	Missense	distal	5	no	10.548	10.424	EPSD	ICGC;COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q12772	SREBF2	P27361	MAPK3	S846	H845R	845	Missense	proximal	-1	no	10.548	10.545	EPSD	ICGC;COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q12772	SREBF2	P27361	MAPK3	S855	R860S	860	Missense	distal	5	no	15.976	16.120	EPSD	ICGC;COSMIC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q12772	SREBF2	P27361	MAPK3	S855	D849N	849	Missense	distal	-6	no	15.976	15.914	EPSD	ICGC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q12772	SREBF2	P27361	MAPK3	S855	V851M	851	Missense	distal	-4	no	15.976	15.948	EPSD	ICGC;COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q12772	SREBF2	P27361	MAPK3	S855	M854L	854	Missense	proximal	-1	no	15.976	16.042	EPSD	ICGC;CCLE	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q12772	SREBF2	P27361	MAPK3	S855	S859F	859	Missense	distal	4	no	15.976	15.561	EPSD	ICGC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q12772	SREBF2	P27361	MAPK3	S914	S914G	914	Missense	central	0	yes	17.229	0.000	EPSD	ICGC;COSMIC	9.358	Loss
CMGC_MAPK_ERK1_MAPK3_ST	Q12772	SREBF2	P27361	MAPK3	S1046	R1040C	1040	Missense	distal	-6	no	14.561	14.162	EPSD	ICGC;COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q12772	SREBF2	P27361	MAPK3	S1046	H1051L	1051	Missense	distal	5	no	14.561	14.398	EPSD	ICGC;COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P05787	KRT8	P27361	MAPK3	S24	R23C	23	Missense	proximal	-1	no	11.213	11.028	EPSD	ICGC;COSMIC;GDSC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P05787	KRT8	P27361	MAPK3	T26	R23C	23	Missense	distal	-3	no	9.689	9.549	EPSD	ICGC;COSMIC;GDSC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P05787	KRT8	P27361	MAPK3	S31	S36W	36	Missense	distal	5	no	10.269	9.658	EPSD	ICGC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P05787	KRT8	P27361	MAPK3	S31	S37C	37	Missense	distal	6	no	10.269	9.402	EPSD	ICGC;COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P05787	KRT8	P27361	MAPK3	S37	S36W	36	Missense	proximal	-1	no	11.111	10.831	EPSD	ICGC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P05787	KRT8	P27361	MAPK3	S37	S37C	37	Missense	central	0	yes	11.111	0.000	EPSD	ICGC;COSMIC	9.358	Loss
CMGC_MAPK_ERK1_MAPK3_ST	P05787	KRT8	P27361	MAPK3	S432	L435I	435	Missense	distal	3	no	15.714	15.694	PhosphoSitePlus	ICGC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P05787	KRT8	P27361	MAPK3	S436	L435I	435	Missense	proximal	-1	no	10.523	10.480	EPSD	ICGC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P05787	KRT8	P27361	MAPK3	S451	A447T	447	Missense	distal	-4	no	12.153	12.227	EPSD	ICGC;CCLE	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P05787	KRT8	P27361	MAPK3	S477	S477A	477	Missense	central	0	yes	11.362	0.000	EPSD	ICGC;COSMIC	9.358	Loss
CMGC_MAPK_ERK1_MAPK3_ST	P05787	KRT8	P27361	MAPK3	S477	P482L	482	Missense	distal	5	no	11.362	11.135	EPSD	ICGC;COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P06401	PGR	P27361	MAPK3	S20	G17S	17	Missense	distal	-3	no	18.590	18.622	EPSD	ICGC;COSMIC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P06401	PGR	P27361	MAPK3	S20	V14M	14	Missense	distal	-6	no	18.590	18.498	EPSD	ICGC;COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P06401	PGR	P27361	MAPK3	S130	Q126K	126	Missense	distal	-4	no	15.019	15.002	EPSD	ICGC;COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P06401	PGR	P27361	MAPK3	S162	S168Y	168	Missense	distal	6	no	16.966	16.584	EPSD	ICGC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P06401	PGR	P27361	MAPK3	S162	L164I	164	Missense	proximal	2	no	16.966	16.954	EPSD	ICGC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P06401	PGR	P27361	MAPK3	S190	L189M	189	Missense	proximal	-1	no	15.067	15.000	EPSD	ICGC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P06401	PGR	P27361	MAPK3	S190	K183N	183	Missense	distal	-7	no	15.067	15.050	EPSD	ICGC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P06401	PGR	P27361	MAPK3	S213	A208T	208	Missense	distal	-5	no	15.680	15.763	EPSD	ICGC;COSMIC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P06401	PGR	P27361	MAPK3	S213	G207R	207	Missense	distal	-6	no	15.680	15.582	EPSD	ICGC;GDSC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P06401	PGR	P27361	MAPK3	S294	T299M	299	Missense	distal	5	no	17.200	16.945	PhosphoSitePlus	ICGC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P06401	PGR	P27361	MAPK3	S294	P291L	291	Missense	distal	-3	no	17.200	17.116	PhosphoSitePlus	ICGC;COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P06401	PGR	P27361	MAPK3	S294	A287T	287	Missense	distal	-7	no	17.200	17.126	PhosphoSitePlus	ICGC;GDSC;CCLE	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P06401	PGR	P27361	MAPK3	S328	G334R	334	Missense	distal	6	no	10.883	10.874	EPSD	ICGC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P06401	PGR	P27361	MAPK3	S328	A335T	335	Missense	distal	7	no	10.883	10.656	EPSD	ICGC;COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P06401	PGR	P27361	MAPK3	S328	E327K	327	Missense	proximal	-1	no	10.883	10.853	EPSD	ICGC;COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P06401	PGR	P27361	MAPK3	S328	G332V	332	Missense	distal	4	no	10.883	10.820	EPSD	ICGC;COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P06401	PGR	P27361	MAPK3	S345	R343W	343	Missense	proximal	-2	no	15.926	14.030	EPSD	ICGC;COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P06401	PGR	P27361	MAPK3	S345	P341L	341	Missense	distal	-4	no	15.926	15.813	EPSD	ICGC;COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P06401	PGR	P27361	MAPK3	S345	P341T	341	Missense	distal	-4	no	15.926	15.895	EPSD	ICGC;COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P06401	PGR	P27361	MAPK3	S345	P352Q	352	Missense	distal	7	no	15.926	16.048	EPSD	ICGC;COSMIC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P06401	PGR	P27361	MAPK3	T351	P352Q	352	Missense	proximal	1	no	17.189	9.245	EPSD	ICGC;COSMIC	9.358	Loss
CMGC_MAPK_ERK1_MAPK3_ST	P06401	PGR	P27361	MAPK3	S400	S400F	400	Missense	central	0	yes	13.499	0.000	EPSD	ICGC;COSMIC	9.358	Loss
CMGC_MAPK_ERK1_MAPK3_ST	P06401	PGR	P27361	MAPK3	S554	E560D	560	Missense	distal	6	no	17.793	17.748	EPSD	ICGC;COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P06401	PGR	P27361	MAPK3	S554	P555Q	555	Missense	proximal	1	no	17.793	9.849	EPSD	ICGC;COSMIC;GDSC;CCLE	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P06401	PGR	P27361	MAPK3	S558	E560D	560	Missense	proximal	2	no	10.925	10.922	EPSD	ICGC;COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P06401	PGR	P27361	MAPK3	S558	P563L	563	Missense	distal	5	no	10.925	10.697	EPSD	ICGC;COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P06401	PGR	P27361	MAPK3	S558	P563T	563	Missense	distal	5	no	10.925	10.833	EPSD	ICGC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P06401	PGR	P27361	MAPK3	S558	P555Q	555	Missense	distal	-3	no	10.925	10.871	EPSD	ICGC;COSMIC;GDSC;CCLE	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q15596	NCOA2	P27361	MAPK3	S29	P30T	30	Missense	proximal	1	no	17.592	8.715	EPSD	ICGC	9.358	Loss
CMGC_MAPK_ERK1_MAPK3_ST	Q15596	NCOA2	P27361	MAPK3	T197	H196N	196	Missense	proximal	-1	no	10.003	9.993	EPSD	ICGC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q15596	NCOA2	P27361	MAPK3	T197	S195R	195	Missense	proximal	-2	no	10.003	9.679	EPSD	ICGC;COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q15596	NCOA2	P27361	MAPK3	S267	R273C	273	Missense	distal	6	no	9.697	9.072	EPSD	ICGC;COSMIC	9.358	Loss
CMGC_MAPK_ERK1_MAPK3_ST	Q15596	NCOA2	P27361	MAPK3	S267	T271N	271	Missense	distal	4	no	9.697	9.664	EPSD	ICGC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q15596	NCOA2	P27361	MAPK3	S267	P262Q	262	Missense	distal	-5	no	9.697	9.649	EPSD	ICGC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q15596	NCOA2	P27361	MAPK3	S269	R273C	273	Missense	distal	4	no	10.984	10.628	EPSD	ICGC;COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q15596	NCOA2	P27361	MAPK3	S269	T271N	271	Missense	proximal	2	no	10.984	10.978	EPSD	ICGC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q15596	NCOA2	P27361	MAPK3	S269	P262Q	262	Missense	distal	-7	no	10.984	11.029	EPSD	ICGC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q15596	NCOA2	P27361	MAPK3	S269	D275N	275	Missense	distal	6	no	10.984	10.932	EPSD	ICGC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q15596	NCOA2	P27361	MAPK3	S402	P403T	403	Missense	proximal	1	no	16.657	7.780	EPSD	ICGC	9.358	Loss
CMGC_MAPK_ERK1_MAPK3_ST	Q15596	NCOA2	P27361	MAPK3	S402	L395M	395	Missense	distal	-7	no	16.657	16.718	EPSD	ICGC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q15596	NCOA2	P27361	MAPK3	S402	A407P	407	Missense	distal	5	no	16.657	16.870	EPSD	ICGC;COSMIC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q15596	NCOA2	P27361	MAPK3	S402	P403H	403	Missense	proximal	1	no	16.657	8.902	EPSD	ICGC;COSMIC	9.358	Loss
CMGC_MAPK_ERK1_MAPK3_ST	Q15596	NCOA2	P27361	MAPK3	T457	A455E	455	Missense	proximal	-2	no	13.288	13.993	EPSD	ICGC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q15596	NCOA2	P27361	MAPK3	S469	L465I	465	Missense	distal	-4	no	14.720	14.701	EPSD	ICGC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q15596	NCOA2	P27361	MAPK3	S487	P488L	488	Missense	proximal	1	no	14.608	5.570	EPSD	ICGC;COSMIC	9.358	Loss
CMGC_MAPK_ERK1_MAPK3_ST	Q15596	NCOA2	P27361	MAPK3	S487	H490N	490	Missense	distal	3	no	14.608	14.601	EPSD	ICGC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q15596	NCOA2	P27361	MAPK3	S493	S499N	499	Missense	distal	6	no	15.343	15.114	EPSD	ICGC;COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q15596	NCOA2	P27361	MAPK3	S493	P488L	488	Missense	distal	-5	no	15.343	15.288	EPSD	ICGC;COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q15596	NCOA2	P27361	MAPK3	S493	H490N	490	Missense	distal	-3	no	15.343	15.330	EPSD	ICGC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q15596	NCOA2	P27361	MAPK3	S499	S499N	499	Missense	central	0	yes	14.757	0.000	EPSD	ICGC;COSMIC	9.358	Loss
CMGC_MAPK_ERK1_MAPK3_ST	Q15596	NCOA2	P27361	MAPK3	S554	L552S	552	Missense	proximal	-2	no	15.398	15.707	EPSD	ICGC;COSMIC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q15596	NCOA2	P27361	MAPK3	S554	S551L	551	Missense	distal	-3	no	15.398	15.323	EPSD	ICGC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q15596	NCOA2	P27361	MAPK3	S699	A704T	704	Missense	distal	5	no	15.367	15.487	EPSD	ICGC;COSMIC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q15596	NCOA2	P27361	MAPK3	S736	A743T	743	Missense	distal	7	no	18.552	18.324	PhosphoSitePlus	ICGC;COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q15596	NCOA2	P27361	MAPK3	S736	A743E	743	Missense	distal	7	no	18.552	18.310	PhosphoSitePlus	ICGC;COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q15596	NCOA2	P27361	MAPK3	T763	D756Y	756	Missense	distal	-7	no	14.607	14.683	EPSD	ICGC;COSMIC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q15596	NCOA2	P27361	MAPK3	T854	K860I	860	Missense	distal	6	no	15.982	15.620	EPSD	ICGC;COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q15596	NCOA2	P27361	MAPK3	S895	I891T	891	Missense	distal	-4	no	18.373	18.474	EPSD	ICGC;COSMIC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q15596	NCOA2	P27361	MAPK3	S895	L889H	889	Missense	distal	-6	no	18.373	18.540	EPSD	ICGC;COSMIC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q15596	NCOA2	P27361	MAPK3	S895	D890N	890	Missense	distal	-5	no	18.373	18.367	EPSD	ICGC;COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q15596	NCOA2	P27361	MAPK3	S994	S993C	993	Missense	proximal	-1	no	9.916	9.690	EPSD	ICGC;COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q15596	NCOA2	P27361	MAPK3	S994	S987R	987	Missense	distal	-7	no	9.916	9.999	EPSD	ICGC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q15596	NCOA2	P27361	MAPK3	S994	S993R	993	Missense	proximal	-1	no	9.916	9.875	EPSD	ICGC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q15596	NCOA2	P27361	MAPK3	S1059	P1066Q	1066	Missense	distal	7	no	14.165	14.287	EPSD	ICGC;COSMIC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q15596	NCOA2	P27361	MAPK3	S1072	P1068A	1068	Missense	distal	-4	no	15.613	15.509	EPSD	ICGC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q15596	NCOA2	P27361	MAPK3	S1072	S1072F	1072	Missense	central	0	yes	15.613	0.000	EPSD	ICGC;COSMIC	9.358	Loss
CMGC_MAPK_ERK1_MAPK3_ST	Q15596	NCOA2	P27361	MAPK3	S1072	P1066Q	1066	Missense	distal	-6	no	15.613	15.547	EPSD	ICGC;COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q15596	NCOA2	P27361	MAPK3	T1273	S1275N	1275	Missense	proximal	2	no	12.431	12.414	EPSD	ICGC;COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q15596	NCOA2	P27361	MAPK3	T1273	A1278D	1278	Missense	distal	5	no	12.431	12.645	EPSD	ICGC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q15596	NCOA2	P27361	MAPK3	T1273	L1270F	1270	Missense	distal	-3	no	12.431	12.366	EPSD	ICGC;COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P17676	CEBPB	P27361	MAPK3	S76	I73M	73	Missense	distal	-3	no	16.206	16.190	EPSD	ICGC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P17676	CEBPB	P27361	MAPK3	S141	L142P	142	Missense	proximal	1	no	6.842	15.880	EPSD	ICGC;COSMIC	9.358	Gain
CMGC_MAPK_ERK1_MAPK3_ST	P17676	CEBPB	P27361	MAPK3	S228	L224I	224	Missense	distal	-4	no	9.455	9.436	EPSD	ICGC;COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P17676	CEBPB	P27361	MAPK3	S231	L224I	224	Missense	distal	-7	no	17.553	17.600	EPSD	ICGC;COSMIC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P17676	CEBPB	P27361	MAPK3	S231	P238H	238	Missense	distal	7	no	17.553	17.613	EPSD	ICGC;COSMIC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P17676	CEBPB	P27361	MAPK3	T235	P238H	238	Missense	distal	3	no	16.764	16.745	PhosphoSitePlus	ICGC;COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P17676	CEBPB	P27361	MAPK3	S237	P238H	238	Missense	proximal	1	no	16.964	9.208	EPSD	ICGC;COSMIC	9.358	Loss
CMGC_MAPK_ERK1_MAPK3_ST	P36956	SREBF1	P27361	MAPK3	S63	S63F	63	Missense	central	0	yes	19.717	0.000	EPSD	ICGC;COSMIC	9.358	Loss
CMGC_MAPK_ERK1_MAPK3_ST	P36956	SREBF1	P27361	MAPK3	S63	G58D	58	Missense	distal	-5	no	19.717	19.726	EPSD	ICGC;COSMIC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P36956	SREBF1	P27361	MAPK3	S63	G57R	57	Missense	distal	-6	no	19.717	19.619	EPSD	ICGC;COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P36956	SREBF1	P27361	MAPK3	S63	A62D	62	Missense	proximal	-1	no	19.717	19.804	EPSD	ICGC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P36956	SREBF1	P27361	MAPK3	S63	S68P	68	Missense	distal	5	no	19.717	19.674	EPSD	ICGC;COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P36956	SREBF1	P27361	MAPK3	T105	P111T	111	Missense	distal	6	no	13.759	13.733	EPSD	ICGC;COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P36956	SREBF1	P27361	MAPK3	T105	P99H	99	Missense	distal	-6	no	13.759	13.678	EPSD	ICGC;COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P36956	SREBF1	P27361	MAPK3	T105	P111R	111	Missense	distal	6	no	13.759	13.647	EPSD	ICGC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P36956	SREBF1	P27361	MAPK3	T105	S112F	112	Missense	distal	7	no	13.759	14.249	EPSD	ICGC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P36956	SREBF1	P27361	MAPK3	S117	P111T	111	Missense	distal	-6	no	14.822	14.738	PhosphoSitePlus	ICGC;COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P36956	SREBF1	P27361	MAPK3	S117	P111R	111	Missense	distal	-6	no	14.822	14.746	PhosphoSitePlus	ICGC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P36956	SREBF1	P27361	MAPK3	S117	S112F	112	Missense	distal	-5	no	14.822	14.688	PhosphoSitePlus	ICGC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P36956	SREBF1	P27361	MAPK3	S117	P114H	114	Missense	distal	-3	no	14.822	14.782	PhosphoSitePlus	ICGC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P36956	SREBF1	P27361	MAPK3	S117	P118H	118	Missense	proximal	1	no	14.822	7.066	PhosphoSitePlus	ICGC;COSMIC	9.358	Loss
CMGC_MAPK_ERK1_MAPK3_ST	P36956	SREBF1	P27361	MAPK3	S117	A115T	115	Missense	proximal	-2	no	14.822	16.187	PhosphoSitePlus	ICGC;COSMIC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P36956	SREBF1	P27361	MAPK3	S117	P120L	120	Missense	distal	3	no	14.822	14.785	PhosphoSitePlus	ICGC;COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P36956	SREBF1	P27361	MAPK3	S117	S117F	117	Missense	central	0	yes	14.822	0.000	PhosphoSitePlus	ICGC;COSMIC	9.358	Loss
CMGC_MAPK_ERK1_MAPK3_ST	O60504	SORBS3	P27361	MAPK3	S24	L22H	22	Missense	proximal	-2	no	10.905	11.062	EPSD	ICGC;COSMIC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	O60504	SORBS3	P27361	MAPK3	S28	L22H	22	Missense	distal	-6	no	9.957	10.124	EPSD	ICGC;COSMIC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	O60504	SORBS3	P27361	MAPK3	S29	L22H	22	Missense	distal	-7	no	9.439	9.367	EPSD	ICGC;COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	O60504	SORBS3	P27361	MAPK3	T64	G62V	62	Missense	proximal	-2	no	13.317	13.779	EPSD	ICGC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	O60504	SORBS3	P27361	MAPK3	T64	P65L	65	Missense	proximal	1	no	13.317	4.279	EPSD	ICGC	9.358	Loss
CMGC_MAPK_ERK1_MAPK3_ST	O60504	SORBS3	P27361	MAPK3	S97	Q98H	98	Missense	proximal	1	no	9.314	9.502	EPSD	ICGC	9.358	Gain
CMGC_MAPK_ERK1_MAPK3_ST	O60504	SORBS3	P27361	MAPK3	T106	K109N	109	Missense	distal	3	no	9.482	9.485	EPSD	ICGC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	O60504	SORBS3	P27361	MAPK3	T106	R113L	113	Missense	distal	7	no	9.482	9.583	EPSD	ICGC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	O60504	SORBS3	P27361	MAPK3	T106	H99Y	99	Missense	distal	-7	no	9.482	9.529	EPSD	ICGC;COSMIC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	O60504	SORBS3	P27361	MAPK3	S299	S299P	299	Missense	central	0	yes	16.716	0.000	EPSD	ICGC;COSMIC	9.358	Loss
CMGC_MAPK_ERK1_MAPK3_ST	O60504	SORBS3	P27361	MAPK3	S303	S299P	299	Missense	distal	-4	no	14.827	14.800	EPSD	ICGC;COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	O60504	SORBS3	P27361	MAPK3	S337	L338P	338	Missense	proximal	1	no	5.642	14.680	EPSD	ICGC;COSMIC	9.358	Gain
CMGC_MAPK_ERK1_MAPK3_ST	O60504	SORBS3	P27361	MAPK3	S339	S339I	339	Missense	central	0	yes	15.206	0.000	EPSD	ICGC	9.358	Loss
CMGC_MAPK_ERK1_MAPK3_ST	O60504	SORBS3	P27361	MAPK3	S339	L338P	338	Missense	proximal	-1	no	15.206	15.301	EPSD	ICGC;COSMIC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	O60504	SORBS3	P27361	MAPK3	S348	R354M	354	Missense	distal	6	no	15.273	14.866	EPSD	ICGC;COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	O60504	SORBS3	P27361	MAPK3	S361	R354M	354	Missense	distal	-7	no	9.353	9.475	EPSD	ICGC;COSMIC	9.358	Gain
CMGC_MAPK_ERK1_MAPK3_ST	O60504	SORBS3	P27361	MAPK3	S373	S373R	373	Missense	central	0	yes	14.892	0.000	EPSD	ICGC	9.358	Loss
CMGC_MAPK_ERK1_MAPK3_ST	O60504	SORBS3	P27361	MAPK3	S373	G372V	372	Missense	proximal	-1	no	14.892	14.874	EPSD	ICGC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	O60504	SORBS3	P27361	MAPK3	S373	G371R	371	Missense	proximal	-2	no	14.892	15.608	EPSD	ICGC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	O60504	SORBS3	P27361	MAPK3	S508	G503V	503	Missense	distal	-5	no	10.384	10.352	EPSD	ICGC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	O60504	SORBS3	P27361	MAPK3	S508	S513P	513	Missense	distal	5	no	10.384	10.341	EPSD	ICGC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	O60504	SORBS3	P27361	MAPK3	S508	Q502K	502	Missense	distal	-6	no	10.384	10.377	EPSD	ICGC;COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	O60504	SORBS3	P27361	MAPK3	S530	D523N	523	Missense	distal	-7	no	16.232	16.256	EPSD	ICGC;COSMIC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	O60504	SORBS3	P27361	MAPK3	S530	R532H	532	Missense	proximal	2	no	16.232	16.229	EPSD	ICGC;COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	O60504	SORBS3	P27361	MAPK3	S530	R532S	532	Missense	proximal	2	no	16.232	16.244	EPSD	ICGC;COSMIC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	O60504	SORBS3	P27361	MAPK3	S544	S545P	545	Missense	proximal	1	no	6.517	15.571	EPSD	ICGC	9.358	Gain
CMGC_MAPK_ERK1_MAPK3_ST	O60504	SORBS3	P27361	MAPK3	S545	S547L	547	Missense	proximal	2	no	18.021	17.998	EPSD	ICGC;COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	O60504	SORBS3	P27361	MAPK3	S545	S545P	545	Missense	central	0	yes	18.021	0.000	EPSD	ICGC	9.358	Loss
CMGC_MAPK_ERK1_MAPK3_ST	O60504	SORBS3	P27361	MAPK3	S545	R541L	541	Missense	distal	-4	no	18.021	17.958	EPSD	ICGC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	O60504	SORBS3	P27361	MAPK3	S551	S547L	547	Missense	distal	-4	no	16.335	16.195	EPSD	ICGC;COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	O60504	SORBS3	P27361	MAPK3	S551	I556T	556	Missense	distal	5	no	16.335	16.592	EPSD	ICGC;COSMIC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	O60504	SORBS3	P27361	MAPK3	S551	S545P	545	Missense	distal	-6	no	16.335	16.250	EPSD	ICGC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	O60504	SORBS3	P27361	MAPK3	S563	I556T	556	Missense	distal	-7	no	14.694	14.579	EPSD	ICGC;COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	O60504	SORBS3	P27361	MAPK3	T585	G584A	584	Missense	proximal	-1	no	15.686	15.619	EPSD	ICGC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P04150	NR3C1	P27361	MAPK3	T8	E13Q	13	Missense	distal	5	no	15.349	15.228	EPSD	ICGC;COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P04150	NR3C1	P27361	MAPK3	T8	S3F	3	Missense	distal	-5	no	15.349	15.215	EPSD	ICGC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P04150	NR3C1	P27361	MAPK3	S17	E13Q	13	Missense	distal	-4	no	9.363	9.321	EPSD	ICGC;COSMIC	9.358	Loss
CMGC_MAPK_ERK1_MAPK3_ST	P04150	NR3C1	P27361	MAPK3	S17	R23S	23	Missense	distal	6	no	9.363	9.605	EPSD	ICGC;COSMIC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P04150	NR3C1	P27361	MAPK3	S45	A49D	49	Missense	distal	4	no	14.239	14.451	EPSD	ICGC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P04150	NR3C1	P27361	MAPK3	S226	E221K	221	Missense	distal	-5	no	16.907	16.895	PhosphoSitePlus	ICGC;COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P04150	NR3C1	P27361	MAPK3	S226	E231K	231	Missense	distal	5	no	16.907	16.779	PhosphoSitePlus	ICGC;COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P04150	NR3C1	P27361	MAPK3	S267	S269G	269	Missense	proximal	2	no	16.626	16.609	EPSD	ICGC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P04150	NR3C1	P27361	MAPK3	S267	S269N	269	Missense	proximal	2	no	16.626	16.609	EPSD	ICGC;COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P04150	NR3C1	P27361	MAPK3	S404	T411S	411	Missense	distal	7	no	15.097	14.978	EPSD	ICGC;COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P04150	NR3C1	P27361	MAPK3	S408	T411S	411	Missense	distal	3	no	11.181	11.195	EPSD	ICGC;COSMIC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P04150	NR3C1	P27361	MAPK3	T413	T411S	411	Missense	proximal	-2	no	9.451	9.360	EPSD	ICGC;COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P04150	NR3C1	P27361	MAPK3	S508	Q502H	502	Missense	distal	-6	no	9.429	9.415	EPSD	ICGC;COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P04150	NR3C1	P27361	MAPK3	S508	P515T	515	Missense	distal	7	no	9.429	9.470	EPSD	ICGC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P04150	NR3C1	P27361	MAPK3	S508	E510D	510	Missense	proximal	2	no	9.429	9.427	EPSD	ICGC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P04150	NR3C1	P27361	MAPK3	S673	L671P	671	Missense	proximal	-2	no	8.609	9.993	EPSD	ICGC	9.358	Gain
CMGC_MAPK_ERK1_MAPK3_ST	P43364	MAGEA11	P27361	MAPK3	S13	G11W	11	Missense	proximal	-2	no	16.354	15.174	EPSD	ICGC;COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P43364	MAGEA11	P27361	MAPK3	S76	E73Q	73	Missense	distal	-3	no	15.314	15.288	EPSD	ICGC;COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P43364	MAGEA11	P27361	MAPK3	S168	S170R	170	Missense	proximal	2	no	17.154	17.142	EPSD	ICGC;COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P43364	MAGEA11	P27361	MAPK3	S170	E177K	177	Missense	distal	7	no	16.417	16.488	EPSD	ICGC;COSMIC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P43364	MAGEA11	P27361	MAPK3	S170	S170R	170	Missense	central	0	yes	16.417	0.000	EPSD	ICGC;COSMIC	9.358	Loss
CMGC_MAPK_ERK1_MAPK3_ST	P43364	MAGEA11	P27361	MAPK3	S174	E177K	177	Missense	distal	3	no	17.385	17.374	PhosphoSitePlus	ICGC;COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P43364	MAGEA11	P27361	MAPK3	S174	S170R	170	Missense	distal	-4	no	17.385	17.308	PhosphoSitePlus	ICGC;COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P43364	MAGEA11	P27361	MAPK3	S181	E177K	177	Missense	distal	-4	no	15.962	15.902	EPSD	ICGC;COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P43364	MAGEA11	P27361	MAPK3	S208	K202E	202	Missense	distal	-6	no	15.720	15.862	EPSD	ICGC;COSMIC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P43364	MAGEA11	P27361	MAPK3	S216	I221T	221	Missense	distal	5	no	12.555	12.812	EPSD	ICGC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P10242	MYB	P27361	MAPK3	S370	M375I	375	Missense	distal	5	no	15.888	15.886	EPSD	ICGC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P10242	MYB	P27361	MAPK3	S370	C374F	374	Missense	distal	4	no	15.888	15.978	EPSD	ICGC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P10242	MYB	P27361	MAPK3	T452	S458L	458	Missense	distal	6	no	14.557	14.201	EPSD	ICGC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P10242	MYB	P27361	MAPK3	S463	P464S	464	Missense	proximal	1	no	15.643	6.590	EPSD	ICGC;COSMIC	9.358	Loss
CMGC_MAPK_ERK1_MAPK3_ST	P10242	MYB	P27361	MAPK3	S463	S458L	458	Missense	distal	-5	no	15.643	15.583	EPSD	ICGC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P10242	MYB	P27361	MAPK3	T466	P464S	464	Missense	proximal	-2	no	16.505	15.429	EPSD	ICGC;COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P10242	MYB	P27361	MAPK3	T468	P464S	464	Missense	distal	-4	no	14.934	14.961	EPSD	ICGC;COSMIC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P10242	MYB	P27361	MAPK3	T490	L484I	484	Missense	distal	-6	no	15.901	15.834	EPSD	ICGC;COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P10242	MYB	P27361	MAPK3	S605	E609A	609	Missense	distal	4	no	9.681	9.450	EPSD	ICGC;COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P35568	IRS1	P27361	MAPK3	S295	P293L	293	Missense	proximal	-2	no	10.617	9.233	EPSD	ICGC;COSMIC	9.358	Loss
CMGC_MAPK_ERK1_MAPK3_ST	P35568	IRS1	P27361	MAPK3	S295	P292L	292	Missense	distal	-3	no	10.617	10.533	EPSD	ICGC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P35568	IRS1	P27361	MAPK3	S295	T300P	300	Missense	distal	5	no	10.617	10.709	EPSD	ICGC;COSMIC;GDSC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P35568	IRS1	P27361	MAPK3	S295	V297G	297	Missense	proximal	2	no	10.617	10.625	EPSD	ICGC;COSMIC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P35568	IRS1	P27361	MAPK3	S312	G319R	319	Missense	distal	7	no	14.927	14.957	EPSD	ICGC;COSMIC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P35568	IRS1	P27361	MAPK3	S323	G319R	319	Missense	distal	-4	no	10.232	10.193	EPSD	ICGC;COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P35568	IRS1	P27361	MAPK3	S345	S345N	345	Missense	central	0	yes	17.160	0.000	EPSD	ICGC	9.358	Loss
CMGC_MAPK_ERK1_MAPK3_ST	P35568	IRS1	P27361	MAPK3	S348	H355Q	355	Missense	distal	7	no	17.318	17.381	EPSD	ICGC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P35568	IRS1	P27361	MAPK3	S348	S345N	345	Missense	distal	-3	no	17.318	17.274	EPSD	ICGC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P35568	IRS1	P27361	MAPK3	S383	P389T	389	Missense	distal	6	no	16.168	16.143	EPSD	ICGC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P35568	IRS1	P27361	MAPK3	S388	P389T	389	Missense	proximal	1	no	13.889	5.012	EPSD	ICGC	9.358	Loss
CMGC_MAPK_ERK1_MAPK3_ST	P35568	IRS1	P27361	MAPK3	S388	S393T	393	Missense	distal	5	no	13.889	13.753	EPSD	ICGC;COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P35568	IRS1	P27361	MAPK3	S404	R411L	411	Missense	distal	7	no	9.281	9.382	EPSD	ICGC;COSMIC	9.358	Gain
CMGC_MAPK_ERK1_MAPK3_ST	P35568	IRS1	P27361	MAPK3	S419	S412P	412	Missense	distal	-7	no	14.960	14.998	EPSD	ICGC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P35568	IRS1	P27361	MAPK3	S419	S421R	421	Missense	proximal	2	no	14.960	14.947	EPSD	ICGC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P35568	IRS1	P27361	MAPK3	S419	A414D	414	Missense	distal	-5	no	14.960	15.024	EPSD	ICGC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P35568	IRS1	P27361	MAPK3	S434	D437Y	437	Missense	distal	3	no	15.936	15.917	EPSD	ICGC;COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P35568	IRS1	P27361	MAPK3	T453	R457H	457	Missense	distal	4	no	15.804	15.810	EPSD	ICGC;COSMIC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P35568	IRS1	P27361	MAPK3	T453	A456D	456	Missense	distal	3	no	15.804	15.838	EPSD	ICGC;COSMIC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P35568	IRS1	P27361	MAPK3	T495	R493C	493	Missense	proximal	-2	no	17.120	15.004	EPSD	ICGC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P35568	IRS1	P27361	MAPK3	T495	R493H	493	Missense	proximal	-2	no	17.120	17.293	EPSD	ICGC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P35568	IRS1	P27361	MAPK3	S531	S531Y	531	Missense	central	0	yes	14.834	0.000	EPSD	ICGC	9.358	Loss
CMGC_MAPK_ERK1_MAPK3_ST	P35568	IRS1	P27361	MAPK3	S603	R600H	600	Missense	distal	-3	no	9.681	9.687	EPSD	ICGC;COSMIC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P35568	IRS1	P27361	MAPK3	S636	P634S	634	Missense	proximal	-2	no	16.332	15.256	EPSD	ICGC;COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P35568	IRS1	P27361	MAPK3	S636	Y632C	632	Missense	distal	-4	no	16.332	16.197	EPSD	ICGC;COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P35568	IRS1	P27361	MAPK3	S639	Y632C	632	Missense	distal	-7	no	9.208	9.359	EPSD	ICGC;COSMIC	9.358	Gain
CMGC_MAPK_ERK1_MAPK3_ST	P35568	IRS1	P27361	MAPK3	S666	P667H	667	Missense	proximal	1	no	13.469	5.714	EPSD	ICGC;COSMIC	9.358	Loss
CMGC_MAPK_ERK1_MAPK3_ST	P35568	IRS1	P27361	MAPK3	S672	G678V	678	Missense	distal	6	no	15.175	14.969	EPSD	ICGC;COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P35568	IRS1	P27361	MAPK3	S672	D674A	674	Missense	proximal	2	no	15.175	15.148	EPSD	ICGC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P35568	IRS1	P27361	MAPK3	S672	P667H	667	Missense	distal	-5	no	15.175	15.144	EPSD	ICGC;COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P35568	IRS1	P27361	MAPK3	S745	G752S	752	Missense	distal	7	no	15.265	15.126	EPSD	ICGC;COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P35568	IRS1	P27361	MAPK3	S745	P746T	746	Missense	proximal	1	no	15.265	6.388	EPSD	ICGC	9.358	Loss
CMGC_MAPK_ERK1_MAPK3_ST	P35568	IRS1	P27361	MAPK3	S745	P746S	746	Missense	proximal	1	no	15.265	6.212	EPSD	ICGC	9.358	Loss
CMGC_MAPK_ERK1_MAPK3_ST	P35568	IRS1	P27361	MAPK3	S745	D748N	748	Missense	distal	3	no	15.265	15.255	EPSD	ICGC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P35568	IRS1	P27361	MAPK3	S918	C923F	923	Missense	distal	5	no	15.353	15.451	EPSD	ICGC;COSMIC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P35568	IRS1	P27361	MAPK3	S918	S917R	917	Missense	proximal	-1	no	15.353	15.311	EPSD	ICGC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P35568	IRS1	P27361	MAPK3	S918	P924T	924	Missense	distal	6	no	15.353	15.328	EPSD	ICGC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P35568	IRS1	P27361	MAPK3	S918	R922G	922	Missense	distal	4	no	15.353	15.339	EPSD	ICGC;COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P35568	IRS1	P27361	MAPK3	S1000	D1003N	1003	Missense	distal	3	no	10.799	10.789	EPSD	ICGC;COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P35568	IRS1	P27361	MAPK3	S1005	D1003N	1003	Missense	proximal	-2	no	15.382	14.969	EPSD	ICGC;COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P35568	IRS1	P27361	MAPK3	S1043	P1044T	1044	Missense	proximal	1	no	16.583	7.706	EPSD	ICGC;COSMIC	9.358	Loss
CMGC_MAPK_ERK1_MAPK3_ST	P35568	IRS1	P27361	MAPK3	S1078	A1071T	1071	Missense	distal	-7	no	14.980	14.906	EPSD	ICGC;GDSC;CCLE	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P35568	IRS1	P27361	MAPK3	T1107	S1106L	1106	Missense	proximal	-1	no	14.450	14.361	EPSD	ICGC;COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P35568	IRS1	P27361	MAPK3	T1107	R1112W	1112	Missense	distal	5	no	14.450	13.982	EPSD	ICGC;COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P35568	IRS1	P27361	MAPK3	T1107	R1112G	1112	Missense	distal	5	no	14.450	14.529	EPSD	ICGC;COSMIC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P35568	IRS1	P27361	MAPK3	T1196	Q1190K	1190	Missense	distal	-6	no	15.427	15.420	EPSD	ICGC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P35568	IRS1	P27361	MAPK3	S1216	L1211R	1211	Missense	distal	-5	no	9.348	9.362	EPSD	ICGC;COSMIC	9.358	Gain
CMGC_MAPK_ERK1_MAPK3_ST	P35568	IRS1	P27361	MAPK3	S1216	T1219P	1219	Missense	distal	3	no	9.348	9.366	EPSD	ICGC;COSMIC;GDSC	9.358	Gain
CMGC_MAPK_ERK1_MAPK3_ST	P35568	IRS1	P27361	MAPK3	S1218	L1211R	1211	Missense	distal	-7	no	10.887	10.825	EPSD	ICGC;COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P35568	IRS1	P27361	MAPK3	S1218	R1220H	1220	Missense	proximal	2	no	10.887	10.884	EPSD	ICGC;COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P35568	IRS1	P27361	MAPK3	S1218	T1219P	1219	Missense	proximal	1	no	10.887	19.764	EPSD	ICGC;COSMIC;GDSC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P35568	IRS1	P27361	MAPK3	T1219	R1220H	1220	Missense	proximal	1	no	10.236	11.981	EPSD	ICGC;COSMIC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P35568	IRS1	P27361	MAPK3	T1219	T1219P	1219	Missense	central	0	yes	10.236	0.000	EPSD	ICGC;COSMIC;GDSC	9.358	Loss
CMGC_MAPK_ERK1_MAPK3_ST	P35568	IRS1	P27361	MAPK3	S1222	R1220H	1220	Missense	proximal	-2	no	12.032	12.205	EPSD	ICGC;COSMIC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P35568	IRS1	P27361	MAPK3	S1222	T1219P	1219	Missense	distal	-3	no	12.032	12.071	EPSD	ICGC;COSMIC;GDSC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P35568	IRS1	P27361	MAPK3	S1223	R1220H	1220	Missense	distal	-3	no	11.468	11.474	EPSD	ICGC;COSMIC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P35568	IRS1	P27361	MAPK3	S1223	T1219P	1219	Missense	distal	-4	no	11.468	11.499	EPSD	ICGC;COSMIC;GDSC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P35568	IRS1	P27361	MAPK3	S1227	R1220H	1220	Missense	distal	-7	no	10.304	10.293	EPSD	ICGC;COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P35568	IRS1	P27361	MAPK3	S1231	Q1235H	1235	Missense	distal	4	no	9.321	9.372	EPSD	ICGC;COSMIC	9.358	Gain
CMGC_MAPK_ERK1_MAPK3_ST	P46527	CDKN1B	P27361	MAPK3	S10	N8K	8	Missense	proximal	-2	no	14.456	14.136	EPSD	ICGC;COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P46527	CDKN1B	P27361	MAPK3	S106	V109G	109	Missense	distal	3	no	9.902	9.924	EPSD	ICGC;COSMIC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P46527	CDKN1B	P27361	MAPK3	S106	C99W	99	Missense	distal	-7	no	9.902	9.961	EPSD	ICGC;COSMIC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P46527	CDKN1B	P27361	MAPK3	S106	P102T	102	Missense	distal	-4	no	9.902	9.871	EPSD	ICGC;COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P46527	CDKN1B	P27361	MAPK3	S175	G182C	182	Missense	distal	7	no	10.278	10.750	EPSD	ICGC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P46527	CDKN1B	P27361	MAPK3	S175	G177V	177	Missense	proximal	2	no	10.278	10.269	EPSD	ICGC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P46527	CDKN1B	P27361	MAPK3	S175	S178F	178	Missense	distal	3	no	10.278	10.213	EPSD	ICGC;COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P46527	CDKN1B	P27361	MAPK3	S178	V184M	184	Missense	distal	6	no	20.295	20.085	EPSD	ICGC;COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P46527	CDKN1B	P27361	MAPK3	S178	G182C	182	Missense	distal	4	no	20.295	19.952	EPSD	ICGC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P46527	CDKN1B	P27361	MAPK3	S178	G177V	177	Missense	proximal	-1	no	20.295	20.277	EPSD	ICGC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P46527	CDKN1B	P27361	MAPK3	S178	S178F	178	Missense	central	0	yes	20.295	0.000	EPSD	ICGC;COSMIC	9.358	Loss
CMGC_MAPK_ERK1_MAPK3_ST	P46527	CDKN1B	P27361	MAPK3	T187	V184M	184	Missense	distal	-3	no	17.172	17.117	PhosphoSitePlus	ICGC;COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P46527	CDKN1B	P27361	MAPK3	T187	G192V	192	Missense	distal	5	no	17.172	16.970	PhosphoSitePlus	ICGC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P46527	CDKN1B	P27361	MAPK3	T187	G182C	182	Missense	distal	-5	no	17.172	17.054	PhosphoSitePlus	ICGC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P46527	CDKN1B	P27361	MAPK3	T187	P191H	191	Missense	distal	4	no	17.172	17.081	PhosphoSitePlus	ICGC;COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q14934	NFATC4	P27361	MAPK3	S73	R77H	77	Missense	distal	4	no	16.925	16.931	EPSD	ICGC;COSMIC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q14934	NFATC4	P27361	MAPK3	S73	P74L	74	Missense	proximal	1	no	16.925	7.887	EPSD	ICGC;COSMIC	9.358	Loss
CMGC_MAPK_ERK1_MAPK3_ST	Q14934	NFATC4	P27361	MAPK3	S311	P314L	314	Missense	distal	3	no	18.249	18.212	EPSD	ICGC;COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q14934	NFATC4	P27361	MAPK3	S395	P396S	396	Missense	proximal	1	no	13.646	4.593	EPSD	ICGC;COSMIC	9.358	Loss
CMGC_MAPK_ERK1_MAPK3_ST	Q14934	NFATC4	P27361	MAPK3	S592	V598F	598	Missense	distal	6	no	14.486	14.210	EPSD	ICGC;COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q14934	NFATC4	P27361	MAPK3	S592	V588A	588	Missense	distal	-4	no	14.486	14.506	EPSD	ICGC;COSMIC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q14934	NFATC4	P27361	MAPK3	S716	F715C	715	Missense	proximal	-1	no	17.356	17.333	EPSD	ICGC;COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q14934	NFATC4	P27361	MAPK3	S819	P820S	820	Missense	proximal	1	no	18.092	9.038	EPSD	ICGC;COSMIC	9.358	Loss
CMGC_MAPK_ERK1_MAPK3_ST	P02686	MBP	P27361	MAPK3	S19	N22K	22	Missense	distal	3	no	9.539	9.536	EPSD	ICGC;COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P02686	MBP	P27361	MAPK3	S26	N22K	22	Missense	distal	-4	no	9.387	9.364	EPSD	ICGC;COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P02686	MBP	P27361	MAPK3	S26	N31K	31	Missense	distal	5	no	9.387	9.357	EPSD	ICGC;COSMIC	9.358	Loss
CMGC_MAPK_ERK1_MAPK3_ST	P02686	MBP	P27361	MAPK3	T106	T106M	106	Missense	central	0	yes	9.764	0.000	EPSD	ICGC;COSMIC	9.358	Loss
CMGC_MAPK_ERK1_MAPK3_ST	P02686	MBP	P27361	MAPK3	T106	P111H	111	Missense	distal	5	no	9.764	9.699	EPSD	ICGC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P02686	MBP	P27361	MAPK3	T106	T106A	106	Missense	central	0	yes	9.764	0.000	EPSD	ICGC	9.358	Loss
CMGC_MAPK_ERK1_MAPK3_ST	Q9UPT5	EXOC7	P27361	MAPK3	S130	S130R	130	Missense	central	0	yes	16.918	0.000	EPSD	ICGC	9.358	Loss
CMGC_MAPK_ERK1_MAPK3_ST	Q9UPT5	EXOC7	P27361	MAPK3	S250	P248S	248	Missense	proximal	-2	no	18.233	17.157	PhosphoSitePlus	ICGC	9.358	Down-regulation
TKL_RIPK_RIPK3_ST	Q9UER7	DAXX	Q9Y572	RIPK3	S110	R117W	117	Missense	distal	7	no	27.214	26.909	EPSD	ICGC;COSMIC	23.118	Down-regulation
TKL_RIPK_RIPK3_ST	Q9UER7	DAXX	Q9Y572	RIPK3	S110	A116V	116	Missense	distal	6	no	27.214	25.058	EPSD	ICGC	23.118	Down-regulation
TKL_RIPK_RIPK3_ST	Q9UER7	DAXX	Q9Y572	RIPK3	T150	N153S	153	Missense	distal	3	no	18.732	25.937	EPSD	ICGC;COSMIC;GDSC;CCLE	23.118	Gain
TKL_RIPK_RIPK3_ST	Q9UER7	DAXX	Q9Y572	RIPK3	T162	P160T	160	Missense	proximal	-2	no	21.322	26.336	EPSD	ICGC;COSMIC	23.118	Gain
TKL_RIPK_RIPK3_ST	Q9UER7	DAXX	Q9Y572	RIPK3	T181	R182S	182	Missense	proximal	1	no	25.707	24.229	EPSD	ICGC;COSMIC	23.118	Down-regulation
TKL_RIPK_RIPK3_ST	Q9UER7	DAXX	Q9Y572	RIPK3	T181	G183V	183	Missense	proximal	2	no	25.707	25.729	EPSD	ICGC;COSMIC	23.118	Up-regulation
TKL_RIPK_RIPK3_ST	Q9UER7	DAXX	Q9Y572	RIPK3	S632	K631Q	631	Missense	proximal	-1	no	28.632	28.970	EPSD	ICGC	23.118	Up-regulation
TKL_RIPK_RIPK3_ST	Q9UER7	DAXX	Q9Y572	RIPK3	T639	P643T	643	Missense	distal	4	no	25.590	24.574	EPSD	ICGC;COSMIC	23.118	Down-regulation
TKL_RIPK_RIPK3_ST	Q9UER7	DAXX	Q9Y572	RIPK3	S668	P670H	670	Missense	proximal	2	no	51.604	51.506	PhosphoSitePlus	ICGC;COSMIC	23.118	Down-regulation
TKL_RIPK_RIPK3_ST	Q9UER7	DAXX	Q9Y572	RIPK3	S668	S671P	671	Missense	distal	3	no	51.604	39.995	PhosphoSitePlus	ICGC;COSMIC;GDSC;CCLE	23.118	Down-regulation
TKL_RIPK_RIPK3_ST	Q9UER7	DAXX	Q9Y572	RIPK3	S690	T684M	684	Missense	distal	-6	no	26.081	25.926	EPSD	ICGC;COSMIC	23.118	Down-regulation
TKL_RIPK_RIPK3_ST	Q9UER7	DAXX	Q9Y572	RIPK3	T695	L698H	698	Missense	distal	3	no	23.693	19.877	EPSD	ICGC;COSMIC	23.118	Loss
TKL_RIPK_RIPK3_ST	Q9UER7	DAXX	Q9Y572	RIPK3	S739	D738Y	738	Missense	proximal	-1	no	27.218	25.886	EPSD	ICGC	23.118	Down-regulation
TKL_RIPK_RIPK3_ST	Q9Y572	RIPK3	Q9Y572	RIPK3	S199	V194I	194	Missense	distal	-5	no	55.827	56.271	EPSD	ICGC;COSMIC	23.118	Up-regulation
TKL_RIPK_RIPK3_ST	Q9Y572	RIPK3	Q9Y572	RIPK3	T416	T416K	416	Missense	central	0	yes	25.166	0.000	EPSD	ICGC	23.118	Loss
TKL_RIPK_RIPK3_ST	Q9Y572	RIPK3	Q9Y572	RIPK3	T416	S410R	410	Missense	distal	-6	no	25.166	24.734	EPSD	ICGC	23.118	Down-regulation
TKL_RIPK_RIPK3_ST	Q9Y572	RIPK3	Q9Y572	RIPK3	T416	P409H	409	Missense	distal	-7	no	25.166	25.801	EPSD	ICGC;COSMIC	23.118	Up-regulation
TKL_RIPK_RIPK3_ST	Q8NB16	MLKL	Q9Y572	RIPK3	S358	R365T	365	Missense	distal	7	no	47.147	47.282	EPSD;PhosphoSitePlus	ICGC;COSMIC	23.118	Up-regulation
STE_STE20_KHS_MAP4K1_ST	Q16584	MAP3K11	Q92918	MAP4K1	S281	A287V	287	Missense	distal	6	no	7.980	6.946	PhosphoSitePlus	ICGC	2.024	Down-regulation
STE_STE20_KHS_MAP4K1_ST	Q16584	MAP3K11	Q92918	MAP4K1	S281	T285N	285	Missense	distal	4	no	7.980	7.907	PhosphoSitePlus	ICGC	2.024	Down-regulation
STE_STE20_KHS_MAP4K1_ST	Q16584	MAP3K11	Q92918	MAP4K1	T526	R529Q	529	Missense	distal	3	no	4.012	3.882	EPSD	ICGC;COSMIC	2.024	Down-regulation
STE_STE20_KHS_MAP4K1_ST	Q16584	MAP3K11	Q92918	MAP4K1	T526	T526A	526	Missense	central	0	yes	4.012	0.000	EPSD	ICGC	2.024	Loss
STE_STE20_KHS_MAP4K1_ST	Q16584	MAP3K11	Q92918	MAP4K1	T526	A532D	532	Missense	distal	6	no	4.012	2.945	EPSD	ICGC	2.024	Down-regulation
STE_STE20_KHS_MAP4K1_ST	Q16584	MAP3K11	Q92918	MAP4K1	T526	R529P	529	Missense	distal	3	no	4.012	4.027	EPSD	ICGC;COSMIC	2.024	Up-regulation
STE_STE20_KHS_MAP4K1_ST	Q16584	MAP3K11	Q92918	MAP4K1	S746	T752A	752	Missense	distal	6	no	2.845	2.941	EPSD	ICGC	2.024	Up-regulation
STE_STE20_KHS_MAP4K1_ST	Q16584	MAP3K11	Q92918	MAP4K1	S746	G751S	751	Missense	distal	5	no	2.845	2.944	EPSD	ICGC	2.024	Up-regulation
STE_STE20_KHS_MAP4K1_ST	Q16584	MAP3K11	Q92918	MAP4K1	T752	G751S	751	Missense	proximal	-1	no	1.686	2.070	EPSD	ICGC	2.024	Gain
STE_STE20_KHS_MAP4K1_ST	Q9BXL7	CARD11	Q92918	MAP4K1	S212	A218E	218	Missense	distal	6	no	2.422	1.653	EPSD	ICGC;COSMIC	2.024	Loss
STE_STE20_KHS_MAP4K1_ST	Q9BXL7	CARD11	Q92918	MAP4K1	S212	K215Q	215	Missense	distal	3	no	2.422	2.405	EPSD	ICGC;COSMIC	2.024	Down-regulation
STE_STE20_KHS_MAP4K1_ST	Q9BXL7	CARD11	Q92918	MAP4K1	S212	A218V	218	Missense	distal	6	no	2.422	1.388	EPSD	ICGC;CCLE	2.024	Loss
STE_STE20_KHS_MAP4K1_ST	Q9BXL7	CARD11	Q92918	MAP4K1	S433	S439A	439	Missense	distal	6	no	2.160	1.828	EPSD	ICGC;COSMIC	2.024	Loss
STE_STE20_KHS_MAP4K1_ST	Q9BXL7	CARD11	Q92918	MAP4K1	S433	S433G	433	Missense	central	0	yes	2.160	0.000	EPSD	ICGC;COSMIC	2.024	Loss
STE_STE20_KHS_MAP4K1_ST	Q9BXL7	CARD11	Q92918	MAP4K1	T532	E528D	528	Missense	distal	-4	no	2.288	1.946	EPSD	ICGC;COSMIC	2.024	Loss
STE_STE20_KHS_MAP4K1_ST	Q9BXL7	CARD11	Q92918	MAP4K1	T532	G526W	526	Missense	distal	-6	no	2.288	2.497	EPSD	ICGC;COSMIC	2.024	Up-regulation
STE_STE20_KHS_MAP4K1_ST	Q9BXL7	CARD11	Q92918	MAP4K1	T532	A534S	534	Missense	proximal	2	no	2.288	2.227	EPSD	ICGC;COSMIC	2.024	Down-regulation
STE_STE20_KHS_MAP4K1_ST	Q9BXL7	CARD11	Q92918	MAP4K1	S535	E528D	528	Missense	distal	-7	no	3.463	3.416	EPSD	ICGC;COSMIC	2.024	Down-regulation
STE_STE20_KHS_MAP4K1_ST	Q9BXL7	CARD11	Q92918	MAP4K1	S535	A534S	534	Missense	proximal	-1	no	3.463	3.396	EPSD	ICGC;COSMIC	2.024	Down-regulation
STE_STE20_KHS_MAP4K1_ST	Q9BXL7	CARD11	Q92918	MAP4K1	T545	N546K	546	Missense	proximal	1	no	1.870	2.112	EPSD	ICGC	2.024	Gain
STE_STE20_KHS_MAP4K1_ST	Q9BXL7	CARD11	Q92918	MAP4K1	S556	Q552K	552	Missense	distal	-4	no	7.521	7.374	PhosphoSitePlus;EPSD	ICGC	2.024	Down-regulation
STE_STE20_KHS_MAP4K1_ST	Q9BXL7	CARD11	Q92918	MAP4K1	S556	P553L	553	Missense	distal	-3	no	7.521	7.512	PhosphoSitePlus;EPSD	ICGC	2.024	Down-regulation
STE_STE20_KHS_MAP4K1_ST	Q9BXL7	CARD11	Q92918	MAP4K1	S558	A565S	565	Missense	distal	7	no	8.222	8.231	EPSD;PhosphoSitePlus	ICGC;COSMIC	2.024	Up-regulation
STE_STE20_KHS_MAP4K1_ST	Q9BXL7	CARD11	Q92918	MAP4K1	S558	Q552K	552	Missense	distal	-6	no	8.222	8.171	EPSD;PhosphoSitePlus	ICGC	2.024	Down-regulation
STE_STE20_KHS_MAP4K1_ST	Q9BXL7	CARD11	Q92918	MAP4K1	S558	P553L	553	Missense	distal	-5	no	8.222	8.302	EPSD;PhosphoSitePlus	ICGC	2.024	Up-regulation
STE_STE20_KHS_MAP4K1_ST	Q9BXL7	CARD11	Q92918	MAP4K1	T564	P568L	568	Missense	distal	4	no	3.729	3.630	EPSD	ICGC;COSMIC	2.024	Down-regulation
STE_STE20_KHS_MAP4K1_ST	Q9BXL7	CARD11	Q92918	MAP4K1	T564	A565S	565	Missense	proximal	1	no	3.729	3.473	EPSD	ICGC;COSMIC	2.024	Down-regulation
STE_STE20_KHS_MAP4K1_ST	Q9BXL7	CARD11	Q92918	MAP4K1	S615	S620F	620	Missense	distal	5	no	2.675	2.649	EPSD	ICGC	2.024	Down-regulation
STE_STE20_KHS_MAP4K1_ST	Q9BXL7	CARD11	Q92918	MAP4K1	S615	S610C	610	Missense	distal	-5	no	2.675	2.852	EPSD	ICGC;COSMIC	2.024	Up-regulation
STE_STE20_KHS_MAP4K1_ST	Q9BXL7	CARD11	Q92918	MAP4K1	S644	R650W	650	Missense	distal	6	no	1.399	2.183	EPSD	ICGC;COSMIC;GDSC;CCLE	2.024	Gain
STE_STE20_KHS_MAP4K1_ST	Q9BXL7	CARD11	Q92918	MAP4K1	S652	V659M	659	Missense	distal	7	no	3.120	3.125	EPSD	ICGC;COSMIC	2.024	Up-regulation
STE_STE20_KHS_MAP4K1_ST	Q9BXL7	CARD11	Q92918	MAP4K1	S652	R650W	650	Missense	proximal	-2	no	3.120	3.188	EPSD	ICGC;COSMIC;GDSC;CCLE	2.024	Up-regulation
STE_STE20_KHS_MAP4K1_ST	Q9BXL7	CARD11	Q92918	MAP4K1	T864	R869W	869	Missense	distal	5	no	2.650	2.676	EPSD	ICGC;COSMIC	2.024	Up-regulation
STE_STE20_KHS_MAP4K1_ST	Q9BXL7	CARD11	Q92918	MAP4K1	T864	D859E	859	Missense	distal	-5	no	2.650	2.590	EPSD	ICGC;COSMIC	2.024	Down-regulation
STE_STE20_KHS_MAP4K1_ST	Q9BXL7	CARD11	Q92918	MAP4K1	T864	T871N	871	Missense	distal	7	no	2.650	2.639	EPSD	ICGC	2.024	Down-regulation
STE_STE20_KHS_MAP4K1_ST	Q9BXL7	CARD11	Q92918	MAP4K1	T864	E857D	857	Missense	distal	-7	no	2.650	2.603	EPSD	ICGC;COSMIC	2.024	Down-regulation
STE_STE20_KHS_MAP4K1_ST	Q9BXL7	CARD11	Q92918	MAP4K1	T880	E876K	876	Missense	distal	-4	no	2.799	2.529	EPSD	ICGC;COSMIC	2.024	Down-regulation
STE_STE20_KHS_MAP4K1_ST	Q9BXL7	CARD11	Q92918	MAP4K1	T880	A877E	877	Missense	distal	-3	no	2.799	2.853	EPSD	ICGC;COSMIC	2.024	Up-regulation
STE_STE20_KHS_MAP4K1_ST	Q9BXL7	CARD11	Q92918	MAP4K1	S923	E917V	917	Missense	distal	-6	no	2.838	2.604	EPSD	ICGC;COSMIC	2.024	Down-regulation
STE_STE20_KHS_MAP4K1_ST	Q9BXL7	CARD11	Q92918	MAP4K1	T1020	R1027L	1027	Missense	distal	7	no	2.283	2.279	EPSD	ICGC	2.024	Down-regulation
STE_STE20_KHS_MAP4K1_ST	Q9BXL7	CARD11	Q92918	MAP4K1	T1020	S1026Y	1026	Missense	distal	6	no	2.283	0.892	EPSD	ICGC;COSMIC	2.024	Loss
STE_STE20_KHS_MAP4K1_ST	Q92918	MAP4K1	Q92918	MAP4K1	S320	H322R	322	Missense	proximal	2	no	2.186	2.271	EPSD	ICGC	2.024	Up-regulation
STE_STE20_KHS_MAP4K1_ST	Q92918	MAP4K1	Q92918	MAP4K1	S407	P406Q	406	Missense	proximal	-1	no	2.828	2.899	EPSD	ICGC	2.024	Up-regulation
STE_STE20_KHS_MAP4K1_ST	Q92918	MAP4K1	Q92918	MAP4K1	S407	M414I	414	Missense	distal	7	no	2.828	2.821	EPSD	ICGC;COSMIC	2.024	Down-regulation
STE_STE20_KHS_MAP4K1_ST	Q92918	MAP4K1	Q92918	MAP4K1	S407	G412V	412	Missense	distal	5	no	2.828	2.958	EPSD	ICGC;COSMIC	2.024	Up-regulation
STE_STE20_KHS_MAP4K1_ST	Q92918	MAP4K1	Q92918	MAP4K1	S430	R427W	427	Missense	distal	-3	no	2.575	2.526	EPSD	ICGC;COSMIC;GDSC;CCLE	2.024	Down-regulation
STE_STE20_KHS_MAP4K1_ST	Q92918	MAP4K1	Q92918	MAP4K1	S444	R438C	438	Missense	distal	-6	no	1.914	2.225	EPSD	ICGC;GDSC;CCLE	2.024	Gain
STE_STE20_KHS_MAP4K1_ST	Q92918	MAP4K1	Q92918	MAP4K1	T445	S447R	447	Missense	proximal	2	no	2.333	1.895	EPSD	ICGC	2.024	Loss
STE_STE20_KHS_MAP4K1_ST	Q92918	MAP4K1	Q92918	MAP4K1	T445	R438C	438	Missense	distal	-7	no	2.333	2.457	EPSD	ICGC;GDSC;CCLE	2.024	Up-regulation
STE_STE20_KHS_MAP4K1_ST	Q92918	MAP4K1	Q92918	MAP4K1	S447	S447R	447	Missense	central	0	yes	2.900	0.000	EPSD	ICGC	2.024	Loss
STE_STE20_KHS_MAP4K1_ST	Q92918	MAP4K1	Q92918	MAP4K1	T451	S447R	447	Missense	distal	-4	no	3.361	3.228	EPSD	ICGC	2.024	Down-regulation
STE_STE20_KHS_MAP4K1_ST	Q92918	MAP4K1	Q92918	MAP4K1	T451	S457P	457	Missense	distal	6	no	3.361	1.721	EPSD	ICGC;COSMIC	2.024	Loss
STE_STE20_KHS_MAP4K1_ST	Q92918	MAP4K1	Q92918	MAP4K1	S463	P461S	461	Missense	proximal	-2	no	2.243	2.347	EPSD	ICGC	2.024	Up-regulation
STE_STE20_KHS_MAP4K1_ST	Q92918	MAP4K1	Q92918	MAP4K1	S463	S457P	457	Missense	distal	-6	no	2.243	1.527	EPSD	ICGC;COSMIC	2.024	Loss
STE_STE20_KHS_MAP4K1_ST	Q92918	MAP4K1	Q92918	MAP4K1	T599	K605N	605	Missense	distal	6	no	1.767	2.327	EPSD	ICGC	2.024	Gain
STE_STE20_KHS_MAP4K1_ST	Q92918	MAP4K1	Q92918	MAP4K1	S797	G804D	804	Missense	distal	7	no	3.366	3.356	EPSD	ICGC;COSMIC	2.024	Down-regulation
STE_STE20_KHS_MAP4K1_ST	Q13094	LCP2	Q92918	MAP4K1	S169	D175N	175	Missense	distal	6	no	1.683	2.613	EPSD	ICGC;COSMIC	2.024	Gain
STE_STE20_KHS_MAP4K1_ST	Q13094	LCP2	Q92918	MAP4K1	S207	P201S	201	Missense	distal	-6	no	2.004	2.720	EPSD	ICGC	2.024	Gain
STE_STE20_KHS_MAP4K1_ST	Q13094	LCP2	Q92918	MAP4K1	S207	P201Q	201	Missense	distal	-6	no	2.004	2.463	EPSD	ICGC	2.024	Gain
STE_STE20_KHS_MAP4K1_ST	Q13094	LCP2	Q92918	MAP4K1	S207	L209P	209	Missense	proximal	2	no	2.004	2.485	EPSD	ICGC;COSMIC	2.024	Gain
STE_STE20_KHS_MAP4K1_ST	Q13094	LCP2	Q92918	MAP4K1	S246	D244Y	244	Missense	proximal	-2	no	2.359	2.307	EPSD	ICGC	2.024	Down-regulation
STE_STE20_KHS_MAP4K1_ST	Q13094	LCP2	Q92918	MAP4K1	S246	E253D	253	Missense	distal	7	no	2.359	2.348	EPSD	ICGC;COSMIC	2.024	Down-regulation
STE_STE20_KHS_MAP4K1_ST	Q13094	LCP2	Q92918	MAP4K1	S246	R245H	245	Missense	proximal	-1	no	2.359	2.090	EPSD	ICGC;COSMIC	2.024	Down-regulation
STE_STE20_KHS_MAP4K1_ST	Q13094	LCP2	Q92918	MAP4K1	S246	L243V	243	Missense	distal	-3	no	2.359	2.369	EPSD	ICGC;COSMIC	2.024	Up-regulation
STE_STE20_KHS_MAP4K1_ST	Q13094	LCP2	Q92918	MAP4K1	S297	T291M	291	Missense	distal	-6	no	3.146	2.843	EPSD	ICGC;COSMIC;GDSC;CCLE	2.024	Down-regulation
STE_STE20_KHS_MAP4K1_ST	Q13094	LCP2	Q92918	MAP4K1	S344	S346Y	346	Missense	proximal	2	no	2.268	1.750	EPSD	ICGC;COSMIC	2.024	Loss
STE_STE20_KHS_MAP4K1_ST	Q13094	LCP2	Q92918	MAP4K1	S344	P349Q	349	Missense	distal	5	no	2.268	2.466	EPSD	ICGC	2.024	Up-regulation
STE_STE20_KHS_MAP4K1_ST	Q13094	LCP2	Q92918	MAP4K1	S344	T341N	341	Missense	distal	-3	no	2.268	2.304	EPSD	ICGC;COSMIC	2.024	Up-regulation
STE_STE20_KHS_MAP4K1_ST	Q13094	LCP2	Q92918	MAP4K1	S344	S350I	350	Missense	distal	6	no	2.268	0.972	EPSD	ICGC	2.024	Loss
Other_CAMKK_CAMKK-Meta_CAMKK1_ST	Q16566	CAMK4	Q8N5S9	CAMKK1	T200	P205T	205	Missense	distal	5	no	5.150	5.133	PhosphoSitePlus;EPSD	ICGC;COSMIC	1.176	Down-regulation
Other_CAMKK_CAMKK-Meta_CAMKK1_ST	Q16566	CAMK4	Q8N5S9	CAMKK1	T200	K199R	199	Missense	proximal	-1	no	5.150	5.191	PhosphoSitePlus;EPSD	ICGC;COSMIC	1.176	Up-regulation
Other_CAMKK_CAMKK-Meta_CAMKK1_ST	Q16566	CAMK4	Q8N5S9	CAMKK1	T200	P205Q	205	Missense	distal	5	no	5.150	5.133	PhosphoSitePlus;EPSD	ICGC;COSMIC	1.176	Down-regulation
Other_CAMKK_CAMKK-Meta_CAMKK1_ST	Q16566	CAMK4	Q8N5S9	CAMKK1	T204	P205T	205	Missense	proximal	1	no	3.913	3.928	EPSD	ICGC;COSMIC	1.176	Up-regulation
Other_CAMKK_CAMKK-Meta_CAMKK1_ST	Q16566	CAMK4	Q8N5S9	CAMKK1	T204	K199R	199	Missense	distal	-5	no	3.913	3.943	EPSD	ICGC;COSMIC	1.176	Up-regulation
Other_CAMKK_CAMKK-Meta_CAMKK1_ST	Q16566	CAMK4	Q8N5S9	CAMKK1	T204	P205Q	205	Missense	proximal	1	no	3.913	3.900	EPSD	ICGC;COSMIC	1.176	Down-regulation
Other_CAMKK_CAMKK-Meta_CAMKK1_ST	Q8TDC3	BRSK1	Q8N5S9	CAMKK1	T189	G192C	192	Missense	distal	3	no	4.887	4.831	EPSD	ICGC;COSMIC	1.176	Down-regulation
Other_CAMKK_CAMKK-Meta_CAMKK1_ST	Q8TDC3	BRSK1	Q8N5S9	CAMKK1	T189	V182M	182	Missense	distal	-7	no	4.887	4.856	EPSD	ICGC	1.176	Down-regulation
Other_CAMKK_CAMKK-Meta_CAMKK1_ST	Q13131	PRKAA1	Q8N5S9	CAMKK1	T183	N189S	189	Missense	distal	6	no	4.668	4.666	PhosphoSitePlus	ICGC;COSMIC;CCLE	1.176	Down-regulation
Other_CAMKK_CAMKK-Meta_CAMKK1_ST	Q13131	PRKAA1	Q8N5S9	CAMKK1	T183	T183K	183	Missense	central	0	yes	4.668	0.000	PhosphoSitePlus	ICGC	1.176	Loss
Other_CAMKK_CAMKK-Meta_CAMKK1_ST	Q13131	PRKAA1	Q8N5S9	CAMKK1	S184	N189S	189	Missense	distal	5	no	1.189	1.190	EPSD	ICGC;COSMIC;CCLE	1.176	Up-regulation
Other_CAMKK_CAMKK-Meta_CAMKK1_ST	Q13131	PRKAA1	Q8N5S9	CAMKK1	S184	T183K	183	Missense	proximal	-1	no	1.189	1.137	EPSD	ICGC	1.176	Loss
Other_CAMKK_CAMKK-Meta_CAMKK1_ST	Q13131	PRKAA1	Q8N5S9	CAMKK1	T244	Q246E	246	Missense	proximal	2	no	1.490	1.442	EPSD	ICGC;COSMIC	1.176	Down-regulation
Other_CAMKK_CAMKK-Meta_CAMKK1_ST	Q13131	PRKAA1	Q8N5S9	CAMKK1	T244	I241M	241	Missense	distal	-3	no	1.490	1.296	EPSD	ICGC;COSMIC	1.176	Down-regulation
Other_CAMKK_CAMKK-Meta_CAMKK1_ST	Q13131	PRKAA1	Q8N5S9	CAMKK1	T244	Y243C	243	Missense	proximal	-1	no	1.490	1.519	EPSD	ICGC;COSMIC	1.176	Up-regulation
Other_CAMKK_CAMKK-Meta_CAMKK1_ST	Q13131	PRKAA1	Q8N5S9	CAMKK1	T244	T244A	244	Missense	central	0	yes	1.490	0.000	EPSD	ICGC;COSMIC	1.176	Loss
Other_CAMKK_CAMKK-Meta_CAMKK1_ST	Q13131	PRKAA1	Q8N5S9	CAMKK1	S498	S498C	498	Missense	central	0	yes	1.198	0.000	EPSD	ICGC;COSMIC	1.176	Loss
Other_CAMKK_CAMKK-Meta_CAMKK1_ST	Q13131	PRKAA1	Q8N5S9	CAMKK1	S498	R501P	501	Missense	distal	3	no	1.198	1.217	EPSD	ICGC;COSMIC	1.176	Up-regulation
Other_CAMKK_CAMKK-Meta_CAMKK1_ST	Q13131	PRKAA1	Q8N5S9	CAMKK1	S498	C503Y	503	Missense	distal	5	no	1.198	1.200	EPSD	ICGC	1.176	Up-regulation
Other_CAMKK_CAMKK-Meta_CAMKK1_ST	Q13131	PRKAA1	Q8N5S9	CAMKK1	S498	Y500C	500	Missense	proximal	2	no	1.198	1.581	EPSD	ICGC;COSMIC	1.176	Up-regulation
Other_CAMKK_CAMKK-Meta_CAMKK1_ST	Q13131	PRKAA1	Q8N5S9	CAMKK1	S498	R505M	505	Missense	distal	7	no	1.198	1.223	EPSD	ICGC	1.176	Up-regulation
Other_CAMKK_CAMKK-Meta_CAMKK1_ST	Q13131	PRKAA1	Q8N5S9	CAMKK1	T522	S524Y	524	Missense	proximal	2	no	1.486	1.552	EPSD	ICGC;COSMIC	1.176	Up-regulation
Other_CAMKK_CAMKK-Meta_CAMKK1_ST	Q13131	PRKAA1	Q8N5S9	CAMKK1	S524	S530C	530	Missense	distal	6	no	1.448	1.451	EPSD	ICGC;COSMIC	1.176	Up-regulation
Other_CAMKK_CAMKK-Meta_CAMKK1_ST	Q13131	PRKAA1	Q8N5S9	CAMKK1	S524	S524Y	524	Missense	central	0	yes	1.448	0.000	EPSD	ICGC;COSMIC	1.176	Loss
Other_CAMKK_CAMKK-Meta_CAMKK1_ST	Q13131	PRKAA1	Q8N5S9	CAMKK1	S527	S530C	530	Missense	distal	3	no	2.750	2.738	EPSD	ICGC;COSMIC	1.176	Down-regulation
Other_CAMKK_CAMKK-Meta_CAMKK1_ST	Q13131	PRKAA1	Q8N5S9	CAMKK1	S527	S524Y	524	Missense	distal	-3	no	2.750	2.852	EPSD	ICGC;COSMIC	1.176	Up-regulation
Other_CAMKK_CAMKK-Meta_CAMKK1_ST	Q8IU85	CAMK1D	Q8N5S9	CAMKK1	S179	D176Y	176	Missense	distal	-3	no	1.759	2.018	EPSD	ICGC;GDSC;CCLE	1.176	Up-regulation
Other_CAMKK_CAMKK-Meta_CAMKK1_ST	Q8IU85	CAMK1D	Q8N5S9	CAMKK1	S179	M178V	178	Missense	proximal	-1	no	1.759	1.737	EPSD	ICGC;COSMIC	1.176	Down-regulation
Other_CAMKK_CAMKK-Meta_CAMKK1_ST	Q8IU85	CAMK1D	Q8N5S9	CAMKK1	S179	G175E	175	Missense	distal	-4	no	1.759	1.813	EPSD	ICGC	1.176	Up-regulation
Other_CAMKK_CAMKK-Meta_CAMKK1_ST	Q8IU85	CAMK1D	Q8N5S9	CAMKK1	S179	V177D	177	Missense	proximal	-2	no	1.759	1.637	EPSD	ICGC	1.176	Down-regulation
Other_CAMKK_CAMKK-Meta_CAMKK1_ST	Q8IU85	CAMK1D	Q8N5S9	CAMKK1	T180	D176Y	176	Missense	distal	-4	no	4.531	4.428	PhosphoSitePlus	ICGC;GDSC;CCLE	1.176	Down-regulation
Other_CAMKK_CAMKK-Meta_CAMKK1_ST	Q8IU85	CAMK1D	Q8N5S9	CAMKK1	T180	M178V	178	Missense	proximal	-2	no	4.531	4.576	PhosphoSitePlus	ICGC;COSMIC	1.176	Up-regulation
Other_CAMKK_CAMKK-Meta_CAMKK1_ST	Q8IU85	CAMK1D	Q8N5S9	CAMKK1	T180	G175E	175	Missense	distal	-5	no	4.531	4.304	PhosphoSitePlus	ICGC	1.176	Down-regulation
Other_CAMKK_CAMKK-Meta_CAMKK1_ST	Q8IU85	CAMK1D	Q8N5S9	CAMKK1	T180	V177D	177	Missense	distal	-3	no	4.531	4.160	PhosphoSitePlus	ICGC	1.176	Down-regulation
Other_CAMKK_CAMKK-Meta_CAMKK1_ST	Q8IU85	CAMK1D	Q8N5S9	CAMKK1	T184	A189T	189	Missense	distal	5	no	1.972	1.974	EPSD	ICGC	1.176	Up-regulation
Other_CAMKK_CAMKK-Meta_CAMKK1_ST	Q8IU85	CAMK1D	Q8N5S9	CAMKK1	T184	M178V	178	Missense	distal	-6	no	1.972	1.986	EPSD	ICGC;COSMIC	1.176	Up-regulation
Other_CAMKK_CAMKK-Meta_CAMKK1_ST	Q8IU85	CAMK1D	Q8N5S9	CAMKK1	T184	V177D	177	Missense	distal	-7	no	1.972	1.964	EPSD	ICGC	1.176	Down-regulation
CK1_CK1_CK1-D_CSNK1D_ST	O15055	PER2	P48730	CSNK1D	S56	D59E	59	Missense	distal	3	no	12.088	12.410	EPSD	ICGC	11.915	Up-regulation
CK1_CK1_CK1-D_CSNK1D_ST	O15055	PER2	P48730	CSNK1D	S56	T49M	49	Missense	distal	-7	no	12.088	13.136	EPSD	ICGC	11.915	Up-regulation
CK1_CK1_CK1-D_CSNK1D_ST	O15055	PER2	P48730	CSNK1D	S82	L83M	83	Missense	proximal	1	no	14.216	12.893	EPSD	ICGC	11.915	Down-regulation
CK1_CK1_CK1-D_CSNK1D_ST	O15055	PER2	P48730	CSNK1D	S82	P78T	78	Missense	distal	-4	no	14.216	14.284	EPSD	ICGC	11.915	Up-regulation
CK1_CK1_CK1-D_CSNK1D_ST	O15055	PER2	P48730	CSNK1D	S82	A86E	86	Missense	distal	4	no	14.216	14.159	EPSD	ICGC	11.915	Down-regulation
CK1_CK1_CK1-D_CSNK1D_ST	O15055	PER2	P48730	CSNK1D	S627	A624D	624	Missense	distal	-3	no	10.341	13.108	EPSD	ICGC	11.915	Gain
CK1_CK1_CK1-D_CSNK1D_ST	O15055	PER2	P48730	CSNK1D	S662	P657Q	657	Missense	distal	-5	no	13.333	14.005	PhosphoSitePlus;EPSD	ICGC	11.915	Up-regulation
CK1_CK1_CK1-D_CSNK1D_ST	O15055	PER2	P48730	CSNK1D	S662	Q669K	669	Missense	distal	7	no	13.333	12.461	PhosphoSitePlus;EPSD	ICGC;COSMIC	11.915	Down-regulation
CK1_CK1_CK1-D_CSNK1D_ST	O15055	PER2	P48730	CSNK1D	S662	A664E	664	Missense	proximal	2	no	13.333	13.117	PhosphoSitePlus;EPSD	ICGC	11.915	Down-regulation
CK1_CK1_CK1-D_CSNK1D_ST	O15055	PER2	P48730	CSNK1D	S665	Q669K	669	Missense	distal	4	no	14.104	14.058	EPSD;PhosphoSitePlus	ICGC;COSMIC	11.915	Down-regulation
CK1_CK1_CK1-D_CSNK1D_ST	O15055	PER2	P48730	CSNK1D	S665	A664E	664	Missense	proximal	-1	no	14.104	14.145	EPSD;PhosphoSitePlus	ICGC	11.915	Up-regulation
CK1_CK1_CK1-D_CSNK1D_ST	O15055	PER2	P48730	CSNK1D	S668	Q669K	669	Missense	proximal	1	no	15.530	12.835	EPSD;PhosphoSitePlus	ICGC;COSMIC	11.915	Down-regulation
CK1_CK1_CK1-D_CSNK1D_ST	O15055	PER2	P48730	CSNK1D	S668	A664E	664	Missense	distal	-4	no	15.530	15.127	EPSD;PhosphoSitePlus	ICGC	11.915	Down-regulation
CK1_CK1_CK1-D_CSNK1D_ST	O15055	PER2	P48730	CSNK1D	S671	Q669K	669	Missense	proximal	-2	no	12.258	11.296	EPSD	ICGC;COSMIC	11.915	Loss
CK1_CK1_CK1-D_CSNK1D_ST	O15055	PER2	P48730	CSNK1D	S671	A664E	664	Missense	distal	-7	no	12.258	12.760	EPSD	ICGC	11.915	Up-regulation
CK1_CK1_CK1-D_CSNK1D_ST	O15055	PER2	P48730	CSNK1D	S696	A695E	695	Missense	proximal	-1	no	14.592	14.633	EPSD	ICGC;COSMIC	11.915	Up-regulation
CK1_CK1_CK1-D_CSNK1D_ST	O15055	PER2	P48730	CSNK1D	S696	C703Y	703	Missense	distal	7	no	14.592	16.838	EPSD	ICGC	11.915	Up-regulation
CK1_CK1_CK1-D_CSNK1D_ST	O15055	PER2	P48730	CSNK1D	S696	E699D	699	Missense	distal	3	no	14.592	14.270	EPSD	ICGC	11.915	Down-regulation
CK1_CK1_CK1-D_CSNK1D_ST	O15055	PER2	P48730	CSNK1D	S700	A695E	695	Missense	distal	-5	no	11.738	12.342	EPSD	ICGC;COSMIC	11.915	Gain
CK1_CK1_CK1-D_CSNK1D_ST	O15055	PER2	P48730	CSNK1D	T774	T781I	781	Missense	distal	7	no	12.777	10.750	EPSD	ICGC	11.915	Loss
CK1_CK1_CK1-D_CSNK1D_ST	O15055	PER2	P48730	CSNK1D	S977	P979L	979	Missense	proximal	2	no	12.031	11.126	EPSD	ICGC;COSMIC;GDSC;CCLE	11.915	Loss
CK1_CK1_CK1-D_CSNK1D_ST	O15055	PER2	P48730	CSNK1D	S977	P979Q	979	Missense	proximal	2	no	12.031	12.522	EPSD	ICGC	11.915	Up-regulation
CK1_CK1_CK1-D_CSNK1D_ST	O15055	PER2	P48730	CSNK1D	S977	P970Q	970	Missense	distal	-7	no	12.031	11.067	EPSD	ICGC;COSMIC	11.915	Loss
CK1_CK1_CK1-D_CSNK1D_ST	O15055	PER2	P48730	CSNK1D	S977	P978L	978	Missense	proximal	1	no	12.031	11.982	EPSD	ICGC	11.915	Down-regulation
CK1_CK1_CK1-D_CSNK1D_ST	O15055	PER2	P48730	CSNK1D	S986	P979L	979	Missense	distal	-7	no	12.057	9.872	EPSD	ICGC;COSMIC;GDSC;CCLE	11.915	Loss
CK1_CK1_CK1-D_CSNK1D_ST	O15055	PER2	P48730	CSNK1D	S986	P979Q	979	Missense	distal	-7	no	12.057	11.093	EPSD	ICGC	11.915	Loss
CK1_CK1_CK1-D_CSNK1D_ST	O15055	PER2	P48730	CSNK1D	S1236	S1236L	1236	Missense	central	0	yes	12.959	0.000	EPSD	ICGC;COSMIC	11.915	Loss
CK1_CK1_CK1-D_CSNK1D_ST	O15055	PER2	P48730	CSNK1D	S1236	E1234K	1234	Missense	proximal	-2	no	12.959	11.683	EPSD	ICGC;COSMIC;GDSC;CCLE	11.915	Loss
CK1_CK1_CK1-D_CSNK1D_ST	O15055	PER2	P48730	CSNK1D	S1236	S1229Y	1229	Missense	distal	-7	no	12.959	10.527	EPSD	ICGC;COSMIC	11.915	Loss
CK1_CK1_CK1-D_CSNK1D_ST	O15055	PER2	P48730	CSNK1D	S1236	S1233R	1233	Missense	distal	-3	no	12.959	11.771	EPSD	ICGC	11.915	Loss
CK1_CK1_CK1-D_CSNK1D_ST	P27707	DCK	P48730	CSNK1D	S11	E17D	17	Missense	distal	6	no	16.389	15.345	EPSD;PhosphoSitePlus	ICGC;COSMIC	11.915	Down-regulation
CK1_CK1_CK1-D_CSNK1D_ST	P27707	DCK	P48730	CSNK1D	S11	S8R	8	Missense	distal	-3	no	16.389	15.201	EPSD;PhosphoSitePlus	ICGC;COSMIC	11.915	Down-regulation
CK1_CK1_CK1-D_CSNK1D_ST	P27707	DCK	P48730	CSNK1D	S13	R20H	20	Missense	distal	7	no	9.797	12.750	EPSD	ICGC	11.915	Gain
CK1_CK1_CK1-D_CSNK1D_ST	P27707	DCK	P48730	CSNK1D	S15	E17D	17	Missense	proximal	2	no	13.354	13.208	EPSD;PhosphoSitePlus	ICGC;COSMIC	11.915	Down-regulation
CK1_CK1_CK1-D_CSNK1D_ST	P27707	DCK	P48730	CSNK1D	S15	S8R	8	Missense	distal	-7	no	13.354	12.196	EPSD;PhosphoSitePlus	ICGC;COSMIC	11.915	Down-regulation
CK1_CK1_CK1-D_CSNK1D_ST	P27707	DCK	P48730	CSNK1D	S15	R20L	20	Missense	distal	5	no	13.354	12.427	EPSD;PhosphoSitePlus	ICGC	11.915	Down-regulation
CK1_CK1_CK1-D_CSNK1D_ST	P27707	DCK	P48730	CSNK1D	S15	R20H	20	Missense	distal	5	no	13.354	11.921	EPSD;PhosphoSitePlus	ICGC	11.915	Down-regulation
CK1_CK1_CK1-D_CSNK1D_ST	P27707	DCK	P48730	CSNK1D	T19	E17D	17	Missense	proximal	-2	no	16.185	15.814	EPSD	ICGC;COSMIC	11.915	Down-regulation
CK1_CK1_CK1-D_CSNK1D_ST	P27707	DCK	P48730	CSNK1D	T19	R20L	20	Missense	proximal	1	no	16.185	17.116	EPSD	ICGC	11.915	Up-regulation
CK1_CK1_CK1-D_CSNK1D_ST	P27707	DCK	P48730	CSNK1D	T19	R20H	20	Missense	proximal	1	no	16.185	18.305	EPSD	ICGC	11.915	Up-regulation
CK1_CK1_CK1-D_CSNK1D_ST	P27707	DCK	P48730	CSNK1D	T72	T72A	72	Missense	central	0	yes	13.371	0.000	PhosphoSitePlus;EPSD	ICGC;COSMIC	11.915	Loss
CK1_CK1_CK1-D_CSNK1D_ST	P27707	DCK	P48730	CSNK1D	T72	T72K	72	Missense	central	0	yes	13.371	0.000	PhosphoSitePlus;EPSD	ICGC;COSMIC	11.915	Loss
CK1_CK1_CK1-D_CSNK1D_ST	P27707	DCK	P48730	CSNK1D	S74	T72A	72	Missense	proximal	-2	no	14.916	14.574	EPSD;PhosphoSitePlus	ICGC;COSMIC	11.915	Down-regulation
CK1_CK1_CK1-D_CSNK1D_ST	P27707	DCK	P48730	CSNK1D	S74	T72K	72	Missense	proximal	-2	no	14.916	13.114	EPSD;PhosphoSitePlus	ICGC;COSMIC	11.915	Down-regulation
CK1_CK1_CK1-D_CSNK1D_ST	P10636	MAPT	P48730	CSNK1D	S56	P59Q	59	Missense	distal	3	no	16.124	17.443	EPSD	ICGC	11.915	Up-regulation
CK1_CK1_CK1-D_CSNK1D_ST	P10636	MAPT	P48730	CSNK1D	S64	P59Q	59	Missense	distal	-5	no	15.022	15.695	EPSD	ICGC	11.915	Up-regulation
CK1_CK1_CK1-D_CSNK1D_ST	P10636	MAPT	P48730	CSNK1D	T101	P98S	98	Missense	distal	-3	no	9.309	13.309	EPSD	ICGC	11.915	Gain
CK1_CK1_CK1-D_CSNK1D_ST	P10636	MAPT	P48730	CSNK1D	S113	D116E	116	Missense	distal	3	no	16.388	16.709	EPSD	ICGC;COSMIC	11.915	Up-regulation
CK1_CK1_CK1-D_CSNK1D_ST	P10636	MAPT	P48730	CSNK1D	T123	D116E	116	Missense	distal	-7	no	12.455	13.561	EPSD	ICGC;COSMIC	11.915	Up-regulation
CK1_CK1_CK1-D_CSNK1D_ST	P10636	MAPT	P48730	CSNK1D	T123	E127K	127	Missense	distal	4	no	12.455	12.923	EPSD	ICGC	11.915	Up-regulation
CK1_CK1_CK1-D_CSNK1D_ST	P10636	MAPT	P48730	CSNK1D	S171	R164T	164	Missense	distal	-7	no	13.725	13.637	EPSD	ICGC;COSMIC	11.915	Down-regulation
CK1_CK1_CK1-D_CSNK1D_ST	P10636	MAPT	P48730	CSNK1D	S171	A166T	166	Missense	distal	-5	no	13.725	11.864	EPSD	ICGC	11.915	Loss
CK1_CK1_CK1-D_CSNK1D_ST	P10636	MAPT	P48730	CSNK1D	S228	P233H	233	Missense	distal	5	no	15.102	13.475	EPSD	ICGC;COSMIC	11.915	Down-regulation
CK1_CK1_CK1-D_CSNK1D_ST	P10636	MAPT	P48730	CSNK1D	S228	S232F	232	Missense	distal	4	no	15.102	15.525	EPSD	ICGC	11.915	Up-regulation
CK1_CK1_CK1-D_CSNK1D_ST	P10636	MAPT	P48730	CSNK1D	S228	D225N	225	Missense	distal	-3	no	15.102	12.659	EPSD	ICGC	11.915	Down-regulation
CK1_CK1_CK1-D_CSNK1D_ST	P10636	MAPT	P48730	CSNK1D	S228	V224I	224	Missense	distal	-4	no	15.102	15.547	EPSD	ICGC;COSMIC	11.915	Up-regulation
CK1_CK1_CK1-D_CSNK1D_ST	P10636	MAPT	P48730	CSNK1D	S238	P233H	233	Missense	distal	-5	no	14.130	12.175	EPSD	ICGC;COSMIC	11.915	Down-regulation
CK1_CK1_CK1-D_CSNK1D_ST	P10636	MAPT	P48730	CSNK1D	S238	S232F	232	Missense	distal	-6	no	14.130	13.402	EPSD	ICGC	11.915	Down-regulation
CK1_CK1_CK1-D_CSNK1D_ST	P10636	MAPT	P48730	CSNK1D	S238	P239Q	239	Missense	proximal	1	no	14.130	13.671	EPSD	ICGC;COSMIC	11.915	Down-regulation
CK1_CK1_CK1-D_CSNK1D_ST	P10636	MAPT	P48730	CSNK1D	T522	G521R	521	Missense	proximal	-1	no	14.745	14.587	EPSD	ICGC;COSMIC	11.915	Down-regulation
CK1_CK1_CK1-D_CSNK1D_ST	P10636	MAPT	P48730	CSNK1D	S525	G521R	521	Missense	distal	-4	no	12.146	11.930	EPSD	ICGC;COSMIC	11.915	Down-regulation
CK1_CK1_CK1-D_CSNK1D_ST	Q99814	EPAS1	P48730	CSNK1D	S148	G152V	152	Missense	distal	4	no	11.538	12.496	EPSD	ICGC	11.915	Gain
CK1_CK1_CK1-D_CSNK1D_ST	Q99814	EPAS1	P48730	CSNK1D	T164	K157E	157	Missense	distal	-7	no	10.079	12.012	EPSD	ICGC	11.915	Gain
CK1_CK1_CK1-D_CSNK1D_ST	Q99814	EPAS1	P48730	CSNK1D	S696	G691V	691	Missense	distal	-5	no	11.469	12.174	EPSD	ICGC	11.915	Gain
CK1_CK1_CK1-D_CSNK1D_ST	Q13148	TARDBP	P48730	CSNK1D	S20	L27P	27	Missense	distal	7	no	15.835	14.890	EPSD	ICGC;COSMIC	11.915	Down-regulation
CK1_CK1_CK1-D_CSNK1D_ST	Q13148	TARDBP	P48730	CSNK1D	S273	Q269H	269	Missense	distal	-4	no	15.148	14.873	EPSD	ICGC;COSMIC	11.915	Down-regulation
CK1_CK1_CK1-D_CSNK1D_ST	Q13148	TARDBP	P48730	CSNK1D	S273	S273I	273	Missense	central	0	yes	15.148	0.000	EPSD	ICGC	11.915	Loss
CK1_CK1_CK1-D_CSNK1D_ST	O14641	DVL2	P48730	CSNK1D	T39	R37S	37	Missense	proximal	-2	no	11.715	12.430	EPSD	ICGC	11.915	Gain
CK1_CK1_CK1-D_CSNK1D_ST	O14641	DVL2	P48730	CSNK1D	T39	V46F	46	Missense	distal	7	no	11.715	12.346	EPSD	ICGC	11.915	Gain
CK1_CK1_CK1-D_CSNK1D_ST	O14641	DVL2	P48730	CSNK1D	T39	R37H	37	Missense	proximal	-2	no	11.715	13.863	EPSD	ICGC;COSMIC	11.915	Gain
CK1_CK1_CK1-D_CSNK1D_ST	O14641	DVL2	P48730	CSNK1D	S126	R132M	132	Missense	distal	6	no	12.649	16.446	EPSD	ICGC	11.915	Up-regulation
CK1_CK1_CK1-D_CSNK1D_ST	O14641	DVL2	P48730	CSNK1D	S195	A190D	190	Missense	distal	-5	no	12.326	11.909	EPSD	ICGC	11.915	Loss
CK1_CK1_CK1-D_CSNK1D_ST	O14641	DVL2	P48730	CSNK1D	S218	T224K	224	Missense	distal	6	no	10.724	11.988	EPSD	ICGC	11.915	Gain
CK1_CK1_CK1-D_CSNK1D_ST	O14641	DVL2	P48730	CSNK1D	T224	T224K	224	Missense	central	0	yes	12.393	0.000	EPSD;PhosphoSitePlus	ICGC	11.915	Loss
CK1_CK1_CK1-D_CSNK1D_ST	O14641	DVL2	P48730	CSNK1D	T224	Q226K	226	Missense	proximal	2	no	12.393	12.271	EPSD;PhosphoSitePlus	ICGC	11.915	Down-regulation
CK1_CK1_CK1-D_CSNK1D_ST	O14641	DVL2	P48730	CSNK1D	S228	R235H	235	Missense	distal	7	no	11.514	14.467	EPSD	ICGC	11.915	Gain
CK1_CK1_CK1-D_CSNK1D_ST	O14641	DVL2	P48730	CSNK1D	S254	V256I	256	Missense	proximal	2	no	10.786	12.054	EPSD	ICGC;COSMIC	11.915	Gain
CK1_CK1_CK1-D_CSNK1D_ST	O14641	DVL2	P48730	CSNK1D	S286	G292R	292	Missense	distal	6	no	13.541	12.101	EPSD	ICGC	11.915	Down-regulation
CK1_CK1_CK1-D_CSNK1D_ST	O14641	DVL2	P48730	CSNK1D	S398	M399V	399	Missense	proximal	1	no	11.560	13.877	EPSD	ICGC	11.915	Gain
CK1_CK1_CK1-D_CSNK1D_ST	O14641	DVL2	P48730	CSNK1D	T403	M399V	399	Missense	distal	-4	no	12.220	12.039	EPSD	ICGC	11.915	Down-regulation
CK1_CK1_CK1-D_CSNK1D_ST	O14641	DVL2	P48730	CSNK1D	S586	E587D	587	Missense	proximal	1	no	15.874	15.956	EPSD	ICGC;COSMIC	11.915	Up-regulation
CK1_CK1_CK1-D_CSNK1D_ST	O14641	DVL2	P48730	CSNK1D	S589	E587D	587	Missense	proximal	-2	no	13.242	12.871	EPSD	ICGC;COSMIC	11.915	Down-regulation
CK1_CK1_CK1-D_CSNK1D_ST	O14641	DVL2	P48730	CSNK1D	S592	E587D	587	Missense	distal	-5	no	15.097	14.077	EPSD	ICGC;COSMIC	11.915	Down-regulation
CK1_CK1_CK1-D_CSNK1D_ST	O14641	DVL2	P48730	CSNK1D	S594	E587D	587	Missense	distal	-7	no	15.038	13.933	EPSD	ICGC;COSMIC	11.915	Down-regulation
CK1_CK1_CK1-D_CSNK1D_ST	O14641	DVL2	P48730	CSNK1D	S616	G619D	619	Missense	distal	3	no	16.189	16.312	EPSD	ICGC;COSMIC	11.915	Up-regulation
CK1_CK1_CK1-D_CSNK1D_ST	O14641	DVL2	P48730	CSNK1D	S620	G619D	619	Missense	proximal	-1	no	12.404	12.801	EPSD	ICGC;COSMIC	11.915	Up-regulation
CK1_CK1_CK1-D_CSNK1D_ST	O14641	DVL2	P48730	CSNK1D	S638	P645R	645	Missense	distal	7	no	15.008	14.673	EPSD	ICGC;COSMIC	11.915	Down-regulation
CK1_CK1_CK1-D_CSNK1D_ST	O14641	DVL2	P48730	CSNK1D	S648	P645R	645	Missense	distal	-3	no	9.770	12.581	EPSD	ICGC;COSMIC	11.915	Gain
CK1_CK1_CK1-D_CSNK1D_ST	Q00987	MDM2	P48730	CSNK1D	S17	G12R	12	Missense	distal	-5	no	13.405	13.078	EPSD	ICGC;COSMIC	11.915	Down-regulation
CK1_CK1_CK1-D_CSNK1D_ST	Q00987	MDM2	P48730	CSNK1D	S17	D11Y	11	Missense	distal	-6	no	13.405	11.814	EPSD	ICGC	11.915	Loss
CK1_CK1_CK1-D_CSNK1D_ST	Q00987	MDM2	P48730	CSNK1D	S17	T10A	10	Missense	distal	-7	no	13.405	15.127	EPSD	ICGC;COSMIC	11.915	Up-regulation
CK1_CK1_CK1-D_CSNK1D_ST	Q00987	MDM2	P48730	CSNK1D	S190	S190C	190	Missense	central	0	yes	12.818	0.000	EPSD	ICGC;COSMIC	11.915	Loss
CK1_CK1_CK1-D_CSNK1D_ST	Q00987	MDM2	P48730	CSNK1D	S220	S215L	215	Missense	distal	-5	no	18.742	17.102	EPSD;PhosphoSitePlus	ICGC;COSMIC	11.915	Down-regulation
CK1_CK1_CK1-D_CSNK1D_ST	Q00987	MDM2	P48730	CSNK1D	S260	E267K	267	Missense	distal	7	no	12.807	13.048	EPSD;PhosphoSitePlus	ICGC;COSMIC	11.915	Up-regulation
CK1_CK1_CK1-D_CSNK1D_ST	Q00987	MDM2	P48730	CSNK1D	S262	E267K	267	Missense	distal	5	no	16.277	16.401	EPSD;PhosphoSitePlus	ICGC;COSMIC	11.915	Up-regulation
CK1_CK1_CK1-D_CSNK1D_ST	Q00987	MDM2	P48730	CSNK1D	S269	E267K	267	Missense	proximal	-2	no	14.868	13.593	EPSD;PhosphoSitePlus	ICGC;COSMIC	11.915	Down-regulation
CK1_CK1_CK1-D_CSNK1D_ST	Q00987	MDM2	P48730	CSNK1D	T279	E285D	285	Missense	distal	6	no	14.446	13.402	EPSD;PhosphoSitePlus	ICGC;COSMIC	11.915	Down-regulation
CK1_CK1_CK1-D_CSNK1D_ST	Q00987	MDM2	P48730	CSNK1D	S286	E285D	285	Missense	proximal	-1	no	13.625	13.109	EPSD	ICGC;COSMIC	11.915	Down-regulation
CK1_CK1_CK1-D_CSNK1D_ST	Q00987	MDM2	P48730	CSNK1D	S290	E285D	285	Missense	distal	-5	no	17.099	16.079	EPSD;PhosphoSitePlus	ICGC;COSMIC	11.915	Down-regulation
CK1_CK1_CK1-D_CSNK1D_ST	Q00987	MDM2	P48730	CSNK1D	S342	I341V	341	Missense	proximal	-1	no	15.826	15.010	EPSD;PhosphoSitePlus	ICGC;COSMIC	11.915	Down-regulation
CK1_CK1_CK1-D_CSNK1D_ST	Q00987	MDM2	P48730	CSNK1D	S386	E390Q	390	Missense	distal	4	no	17.010	17.523	EPSD;PhosphoSitePlus	ICGC;COSMIC	11.915	Up-regulation
CK1_CK1_CK1-D_CSNK1D_ST	Q00987	MDM2	P48730	CSNK1D	S395	S400C	400	Missense	distal	5	no	11.686	12.043	EPSD	ICGC;COSMIC	11.915	Gain
CK1_CK1_CK1-D_CSNK1D_ST	Q00987	MDM2	P48730	CSNK1D	T419	V426F	426	Missense	distal	7	no	14.470	15.101	EPSD;PhosphoSitePlus	ICGC	11.915	Up-regulation
CK1_CK1_CK1-D_CSNK1D_ST	Q00987	MDM2	P48730	CSNK1D	S425	V426F	426	Missense	proximal	1	no	13.778	11.903	EPSD	ICGC	11.915	Loss
CK1_CK1_CK1-D_CSNK1D_ST	P53041	PPP5C	P48730	CSNK1D	T362	T362A	362	Missense	central	0	yes	13.346	0.000	PhosphoSitePlus	ICGC	11.915	Loss
CK1_CK1_CK1-D_CSNK1D_ST	P53041	PPP5C	P48730	CSNK1D	T362	G360C	360	Missense	proximal	-2	no	13.346	13.720	PhosphoSitePlus	ICGC;COSMIC	11.915	Up-regulation
CK1_CK1_CK1-D_CSNK1D_ST	P56817	BACE1	P48730	CSNK1D	S59	R57H	57	Missense	proximal	-2	no	10.607	12.755	EPSD	ICGC	11.915	Gain
CK1_CK1_CK1-D_CSNK1D_ST	P56817	BACE1	P48730	CSNK1D	S71	D65E	65	Missense	distal	-6	no	11.760	12.447	EPSD	ICGC	11.915	Gain
CK1_CK1_CK1-D_CSNK1D_ST	P25054	APC	P48730	CSNK1D	S5	K11N	11	Missense	distal	6	no	12.628	13.823	EPSD	ICGC	11.915	Up-regulation
CK1_CK1_CK1-D_CSNK1D_ST	P25054	APC	P48730	CSNK1D	S5	A4T	4	Missense	proximal	-1	no	12.628	11.274	EPSD	ICGC;COSMIC	11.915	Loss
CK1_CK1_CK1-D_CSNK1D_ST	P25054	APC	P48730	CSNK1D	S705	K708R	708	Missense	distal	3	no	12.044	10.169	EPSD	ICGC;COSMIC	11.915	Loss
CK1_CK1_CK1-D_CSNK1D_ST	P25054	APC	P48730	CSNK1D	S705	M706R	706	Missense	proximal	1	no	12.044	12.437	EPSD	ICGC;COSMIC	11.915	Up-regulation
CK1_CK1_CK1-D_CSNK1D_ST	P25054	APC	P48730	CSNK1D	S705	I711T	711	Missense	distal	6	no	12.044	11.857	EPSD	ICGC	11.915	Loss
CK1_CK1_CK1-D_CSNK1D_ST	P25054	APC	P48730	CSNK1D	S780	R786C	786	Missense	distal	6	no	12.201	10.126	EPSD	ICGC;COSMIC	11.915	Loss
CK1_CK1_CK1-D_CSNK1D_ST	P25054	APC	P48730	CSNK1D	S905	S900Y	900	Missense	distal	-5	no	12.169	10.989	EPSD	ICGC;COSMIC	11.915	Loss
CK1_CK1_CK1-D_CSNK1D_ST	P25054	APC	P48730	CSNK1D	S905	T910N	910	Missense	distal	5	no	12.169	13.191	EPSD	ICGC;COSMIC	11.915	Up-regulation
CK1_CK1_CK1-D_CSNK1D_ST	P25054	APC	P48730	CSNK1D	S905	S908Y	908	Missense	distal	3	no	12.169	8.340	EPSD	ICGC;COSMIC	11.915	Loss
CK1_CK1_CK1-D_CSNK1D_ST	P25054	APC	P48730	CSNK1D	S987	Y986S	986	Missense	proximal	-1	no	11.866	13.059	EPSD	ICGC	11.915	Gain
CK1_CK1_CK1-D_CSNK1D_ST	P25054	APC	P48730	CSNK1D	S1032	S1028R	1028	Missense	distal	-4	no	15.228	14.721	EPSD	ICGC;COSMIC	11.915	Down-regulation
CK1_CK1_CK1-D_CSNK1D_ST	P25054	APC	P48730	CSNK1D	S1081	E1080K	1080	Missense	proximal	-1	no	12.862	12.076	EPSD	ICGC;COSMIC	11.915	Down-regulation
CK1_CK1_CK1-D_CSNK1D_ST	P25054	APC	P48730	CSNK1D	S1081	P1076H	1076	Missense	distal	-5	no	12.862	10.907	EPSD	ICGC;COSMIC	11.915	Loss
CK1_CK1_CK1-D_CSNK1D_ST	P25054	APC	P48730	CSNK1D	S1081	P1076L	1076	Missense	distal	-5	no	12.862	11.229	EPSD	ICGC;COSMIC	11.915	Loss
CK1_CK1_CK1-D_CSNK1D_ST	P25054	APC	P48730	CSNK1D	S1128	E1132K	1132	Missense	distal	4	no	14.298	14.765	EPSD	ICGC;COSMIC	11.915	Up-regulation
CK1_CK1_CK1-D_CSNK1D_ST	P25054	APC	P48730	CSNK1D	S1128	V1125I	1125	Missense	distal	-3	no	14.298	9.568	EPSD	ICGC;COSMIC	11.915	Loss
CK1_CK1_CK1-D_CSNK1D_ST	P25054	APC	P48730	CSNK1D	T1220	T1218A	1218	Missense	proximal	-2	no	12.367	12.025	EPSD	ICGC;GDSC;CCLE	11.915	Down-regulation
CK1_CK1_CK1-D_CSNK1D_ST	P25054	APC	P48730	CSNK1D	S1222	T1218A	1218	Missense	distal	-4	no	15.401	16.098	EPSD	ICGC;GDSC;CCLE	11.915	Up-regulation
CK1_CK1_CK1-D_CSNK1D_ST	P25054	APC	P48730	CSNK1D	T1301	L1302M	1302	Missense	proximal	1	no	12.823	11.500	EPSD	ICGC;COSMIC	11.915	Loss
CK1_CK1_CK1-D_CSNK1D_ST	P25054	APC	P48730	CSNK1D	S1315	K1310N	1310	Missense	distal	-5	no	10.149	12.394	EPSD	ICGC;COSMIC	11.915	Gain
CK1_CK1_CK1-D_CSNK1D_ST	P25054	APC	P48730	CSNK1D	S1343	S1346L	1346	Missense	distal	3	no	11.943	10.155	EPSD	ICGC;COSMIC	11.915	Loss
CK1_CK1_CK1-D_CSNK1D_ST	P25054	APC	P48730	CSNK1D	S1343	A1347T	1347	Missense	distal	4	no	11.943	12.391	EPSD	ICGC;COSMIC	11.915	Up-regulation
CK1_CK1_CK1-D_CSNK1D_ST	P25054	APC	P48730	CSNK1D	T1368	A1366V	1366	Missense	proximal	-2	no	14.760	12.060	EPSD	ICGC;COSMIC	11.915	Down-regulation
CK1_CK1_CK1-D_CSNK1D_ST	P25054	APC	P48730	CSNK1D	S1389	T1388A	1388	Missense	proximal	-1	no	11.322	12.676	EPSD	ICGC;COSMIC	11.915	Gain
CK1_CK1_CK1-D_CSNK1D_ST	P25054	APC	P48730	CSNK1D	S1539	G1534W	1534	Missense	distal	-5	no	13.822	10.236	EPSD	ICGC;COSMIC	11.915	Loss
CK1_CK1_CK1-D_CSNK1D_ST	P25054	APC	P48730	CSNK1D	S1539	D1532G	1532	Missense	distal	-7	no	13.822	14.604	EPSD	ICGC;COSMIC	11.915	Up-regulation
CK1_CK1_CK1-D_CSNK1D_ST	P25054	APC	P48730	CSNK1D	S1539	E1536D	1536	Missense	distal	-3	no	13.822	14.702	EPSD	ICGC;COSMIC	11.915	Up-regulation
CK1_CK1_CK1-D_CSNK1D_ST	P25054	APC	P48730	CSNK1D	T1556	E1560K	1560	Missense	distal	4	no	12.380	12.848	EPSD	ICGC;COSMIC	11.915	Up-regulation
CK1_CK1_CK1-D_CSNK1D_ST	P25054	APC	P48730	CSNK1D	S1757	S1756F	1756	Missense	proximal	-1	no	12.417	12.929	EPSD	ICGC	11.915	Up-regulation
CK1_CK1_CK1-D_CSNK1D_ST	P25054	APC	P48730	CSNK1D	S1861	R1858L	1858	Missense	distal	-3	no	12.600	11.583	EPSD	ICGC;COSMIC	11.915	Loss
CK1_CK1_CK1-D_CSNK1D_ST	P25054	APC	P48730	CSNK1D	S1863	R1858L	1858	Missense	distal	-5	no	12.254	10.726	EPSD	ICGC;COSMIC	11.915	Loss
CK1_CK1_CK1-D_CSNK1D_ST	P25054	APC	P48730	CSNK1D	S1864	D1871V	1871	Missense	distal	7	no	12.673	12.985	EPSD	ICGC;COSMIC	11.915	Up-regulation
CK1_CK1_CK1-D_CSNK1D_ST	P25054	APC	P48730	CSNK1D	S1864	R1858L	1858	Missense	distal	-6	no	12.673	12.208	EPSD	ICGC;COSMIC	11.915	Down-regulation
CK1_CK1_CK1-D_CSNK1D_ST	P25054	APC	P48730	CSNK1D	S2034	Q2040P	2040	Missense	distal	6	no	12.704	12.006	EPSD	ICGC;COSMIC	11.915	Down-regulation
CK1_CK1_CK1-D_CSNK1D_ST	P25054	APC	P48730	CSNK1D	S2034	S2028I	2028	Missense	distal	-6	no	12.704	11.645	EPSD	ICGC	11.915	Loss
CK1_CK1_CK1-D_CSNK1D_ST	P25054	APC	P48730	CSNK1D	S2034	S2031I	2031	Missense	distal	-3	no	12.704	4.633	EPSD	ICGC;COSMIC	11.915	Loss
CK1_CK1_CK1-D_CSNK1D_ST	P25054	APC	P48730	CSNK1D	S2064	P2065S	2065	Missense	proximal	1	no	13.639	11.320	EPSD	ICGC;COSMIC	11.915	Loss
CK1_CK1_CK1-D_CSNK1D_ST	P25054	APC	P48730	CSNK1D	S2110	I2111T	2111	Missense	proximal	1	no	11.746	12.324	EPSD	ICGC;COSMIC	11.915	Gain
CK1_CK1_CK1-D_CSNK1D_ST	P25054	APC	P48730	CSNK1D	S2113	I2111T	2111	Missense	proximal	-2	no	6.716	12.360	EPSD	ICGC;COSMIC	11.915	Gain
CK1_CK1_CK1-D_CSNK1D_ST	P25054	APC	P48730	CSNK1D	S2307	R2305T	2305	Missense	proximal	-2	no	12.844	15.167	EPSD	ICGC;COSMIC	11.915	Up-regulation
CK1_CK1_CK1-D_CSNK1D_ST	P25054	APC	P48730	CSNK1D	S2307	R2311I	2311	Missense	distal	4	no	12.844	12.528	EPSD	ICGC;COSMIC	11.915	Down-regulation
CK1_CK1_CK1-D_CSNK1D_ST	P25054	APC	P48730	CSNK1D	S2310	R2305T	2305	Missense	distal	-5	no	13.717	12.393	EPSD	ICGC;COSMIC	11.915	Down-regulation
CK1_CK1_CK1-D_CSNK1D_ST	P25054	APC	P48730	CSNK1D	S2310	R2311I	2311	Missense	proximal	1	no	13.717	12.943	EPSD	ICGC;COSMIC	11.915	Down-regulation
CK1_CK1_CK1-D_CSNK1D_ST	P25054	APC	P48730	CSNK1D	S2337	R2333T	2333	Missense	distal	-4	no	13.073	13.184	EPSD	ICGC;COSMIC	11.915	Up-regulation
CK1_CK1_CK1-D_CSNK1D_ST	P25054	APC	P48730	CSNK1D	S2337	P2338H	2338	Missense	proximal	1	no	13.073	14.213	EPSD	ICGC	11.915	Up-regulation
CK1_CK1_CK1-D_CSNK1D_ST	P25054	APC	P48730	CSNK1D	S2337	G2332S	2332	Missense	distal	-5	no	13.073	12.857	EPSD	ICGC	11.915	Down-regulation
CK1_CK1_CK1-D_CSNK1D_ST	P25054	APC	P48730	CSNK1D	S2337	S2330F	2330	Missense	distal	-7	no	13.073	11.993	EPSD	ICGC	11.915	Down-regulation
CK1_CK1_CK1-D_CSNK1D_ST	P25054	APC	P48730	CSNK1D	S2359	M2364I	2364	Missense	distal	5	no	14.602	14.095	EPSD	ICGC;COSMIC	11.915	Down-regulation
CK1_CK1_CK1-D_CSNK1D_ST	P25054	APC	P48730	CSNK1D	S2359	K2357T	2357	Missense	proximal	-2	no	14.602	16.403	EPSD	ICGC;COSMIC	11.915	Up-regulation
CK1_CK1_CK1-D_CSNK1D_ST	P25054	APC	P48730	CSNK1D	S2427	S2432L	2432	Missense	distal	5	no	12.268	11.009	EPSD	ICGC;COSMIC	11.915	Loss
CK1_CK1_CK1-D_CSNK1D_ST	P25054	APC	P48730	CSNK1D	S2427	R2431K	2431	Missense	distal	4	no	12.268	12.263	EPSD	ICGC;COSMIC	11.915	Down-regulation
CK1_CK1_CK1-D_CSNK1D_ST	P25054	APC	P48730	CSNK1D	S2464	S2464C	2464	Missense	central	0	yes	13.202	0.000	EPSD	ICGC;COSMIC	11.915	Loss
CK1_CK1_CK1-D_CSNK1D_ST	P25054	APC	P48730	CSNK1D	S2464	R2470I	2470	Missense	distal	6	no	13.202	13.398	EPSD	ICGC	11.915	Up-regulation
CK1_CK1_CK1-D_CSNK1D_ST	P25054	APC	P48730	CSNK1D	S2464	S2469F	2469	Missense	distal	5	no	13.202	12.722	EPSD	ICGC;COSMIC	11.915	Down-regulation
CK1_CK1_CK1-D_CSNK1D_ST	P25054	APC	P48730	CSNK1D	S2464	S2459F	2459	Missense	distal	-5	no	13.202	12.537	EPSD	ICGC	11.915	Down-regulation
CK1_CK1_CK1-D_CSNK1D_ST	P25054	APC	P48730	CSNK1D	S2468	S2469F	2469	Missense	proximal	1	no	10.524	11.915	EPSD	ICGC;COSMIC	11.915	Gain
CK1_CK1_CK1-D_CSNK1D_ST	P25054	APC	P48730	CSNK1D	T2563	R2566K	2566	Missense	distal	3	no	11.231	13.106	EPSD	ICGC	11.915	Gain
CK1_CK1_CK1-D_CSNK1D_ST	P25054	APC	P48730	CSNK1D	S2580	S2581R	2581	Missense	proximal	1	no	13.437	14.777	EPSD	ICGC;COSMIC	11.915	Up-regulation
CK1_CK1_CK1-D_CSNK1D_ST	P25054	APC	P48730	CSNK1D	S2581	S2581R	2581	Missense	central	0	yes	12.419	0.000	EPSD	ICGC;COSMIC	11.915	Loss
CK1_CK1_CK1-D_CSNK1D_ST	P25054	APC	P48730	CSNK1D	T2629	V2630I	2630	Missense	proximal	1	no	12.809	10.110	EPSD	ICGC;COSMIC	11.915	Loss
CK1_CK1_CK1-D_CSNK1D_ST	P25054	APC	P48730	CSNK1D	T2629	S2625C	2625	Missense	distal	-4	no	12.809	12.718	EPSD	ICGC	11.915	Down-regulation
CK1_CK1_CK1-D_CSNK1D_ST	P25054	APC	P48730	CSNK1D	T2629	G2633C	2633	Missense	distal	4	no	12.809	12.704	EPSD	ICGC;COSMIC	11.915	Down-regulation
CK1_CK1_CK1-D_CSNK1D_ST	P25054	APC	P48730	CSNK1D	S2631	V2630I	2630	Missense	proximal	-1	no	11.893	12.709	EPSD	ICGC;COSMIC	11.915	Gain
CK1_CK1_CK1-D_CSNK1D_ST	P25054	APC	P48730	CSNK1D	T2635	V2630I	2630	Missense	distal	-5	no	12.118	10.055	EPSD	ICGC;COSMIC	11.915	Loss
CK1_CK1_CK1-D_CSNK1D_ST	P25054	APC	P48730	CSNK1D	T2635	K2641N	2641	Missense	distal	6	no	12.118	13.313	EPSD	ICGC;COSMIC	11.915	Up-regulation
CK1_CK1_CK1-D_CSNK1D_ST	P25054	APC	P48730	CSNK1D	T2635	G2633C	2633	Missense	proximal	-2	no	12.118	12.492	EPSD	ICGC;COSMIC	11.915	Up-regulation
CK1_CK1_CK1-D_CSNK1D_ST	P25054	APC	P48730	CSNK1D	T2676	V2682L	2682	Missense	distal	6	no	12.372	13.425	EPSD	ICGC	11.915	Up-regulation
CK1_CK1_CK1-D_CSNK1D_ST	P25054	APC	P48730	CSNK1D	T2676	G2672E	2672	Missense	distal	-4	no	12.372	12.561	EPSD	ICGC	11.915	Up-regulation
CK1_CK1_CK1-D_CSNK1D_ST	P25054	APC	P48730	CSNK1D	S2797	R2791W	2791	Missense	distal	-6	no	12.827	11.298	EPSD	ICGC;COSMIC	11.915	Loss
CK1_CK1_CK1-D_CSNK1D_ST	P25054	APC	P48730	CSNK1D	S2797	S2793I	2793	Missense	distal	-4	no	12.827	12.806	EPSD	ICGC	11.915	Down-regulation
CK1_CK1_CK1-D_CSNK1D_ST	P25054	APC	P48730	CSNK1D	S2797	S2794I	2794	Missense	distal	-3	no	12.827	4.755	EPSD	ICGC;COSMIC	11.915	Loss
CK1_CK1_CK1-D_CSNK1D_ST	P04637	TP53	P48730	CSNK1D	S6	E11K	11	Missense	distal	5	no	15.860	15.984	EPSD	ICGC;COSMIC	11.915	Up-regulation
CK1_CK1_CK1-D_CSNK1D_ST	P04637	TP53	P48730	CSNK1D	S9	E11K	11	Missense	proximal	2	no	18.861	18.099	PhosphoSitePlus;EPSD	ICGC;COSMIC	11.915	Down-regulation
CK1_CK1_CK1-D_CSNK1D_ST	P04637	TP53	P48730	CSNK1D	S15	E11K	11	Missense	distal	-4	no	13.127	12.977	EPSD	ICGC;COSMIC	11.915	Down-regulation
CK1_CK1_CK1-D_CSNK1D_ST	P04637	TP53	P48730	CSNK1D	S20	W23C	23	Missense	distal	3	no	12.521	10.714	EPSD;PhosphoSitePlus	ICGC;COSMIC	11.915	Loss
CK1_CK1_CK1-D_CSNK1D_ST	P04637	TP53	P48730	CSNK1D	S127	T125R	125	Missense	proximal	-2	no	12.589	10.266	EPSD	ICGC;COSMIC	11.915	Loss
CK1_CK1_CK1-D_CSNK1D_ST	P04637	TP53	P48730	CSNK1D	S127	F134C	134	Missense	distal	7	no	12.589	9.187	EPSD	ICGC;COSMIC;CCLE	11.915	Loss
CK1_CK1_CK1-D_CSNK1D_ST	P04637	TP53	P48730	CSNK1D	S127	C124G	124	Missense	distal	-3	no	12.589	13.665	EPSD	ICGC;COSMIC	11.915	Up-regulation
CK1_CK1_CK1-D_CSNK1D_ST	P04637	TP53	P48730	CSNK1D	S127	C124R	124	Missense	distal	-3	no	12.589	13.225	EPSD	ICGC;COSMIC;GDSC;CCLE	11.915	Up-regulation
CK1_CK1_CK1-D_CSNK1D_ST	P04637	TP53	P48730	CSNK1D	S127	L130H	130	Missense	distal	3	no	12.589	13.214	EPSD	ICGC;COSMIC	11.915	Up-regulation
CK1_CK1_CK1-D_CSNK1D_ST	P04637	TP53	P48730	CSNK1D	S127	T125A	125	Missense	proximal	-2	no	12.589	12.247	EPSD	ICGC;COSMIC	11.915	Down-regulation
CK1_CK1_CK1-D_CSNK1D_ST	P04637	TP53	P48730	CSNK1D	S127	K120N	120	Missense	distal	-7	no	12.589	14.280	EPSD	ICGC;COSMIC;GDSC;CCLE	11.915	Up-regulation
CK1_CK1_CK1-D_CSNK1D_ST	P04637	TP53	P48730	CSNK1D	S127	N131Y	131	Missense	distal	4	no	12.589	13.496	EPSD	ICGC;COSMIC	11.915	Up-regulation
CK1_CK1_CK1-D_CSNK1D_ST	P04637	TP53	P48730	CSNK1D	S127	K120M	120	Missense	distal	-7	no	12.589	13.345	EPSD	ICGC;COSMIC	11.915	Up-regulation
CK1_CK1_CK1-D_CSNK1D_ST	P04637	TP53	P48730	CSNK1D	S127	K132M	132	Missense	distal	5	no	12.589	12.857	EPSD	ICGC;COSMIC;CCLE	11.915	Up-regulation
CK1_CK1_CK1-D_CSNK1D_ST	P04637	TP53	P48730	CSNK1D	S127	M133T	133	Missense	distal	6	no	12.589	8.801	EPSD	ICGC;COSMIC	11.915	Loss
CK1_CK1_CK1-D_CSNK1D_ST	P04637	TP53	P48730	CSNK1D	S127	K120R	120	Missense	distal	-7	no	12.589	12.385	EPSD	ICGC;COSMIC	11.915	Down-regulation
CK1_CK1_CK1-D_CSNK1D_ST	P04637	TP53	P48730	CSNK1D	S127	C124Y	124	Missense	distal	-3	no	12.589	13.141	EPSD	ICGC;COSMIC	11.915	Up-regulation
CK1_CK1_CK1-D_CSNK1D_ST	P49810	PSEN2	P48730	CSNK1D	S9	M5T	5	Missense	distal	-4	no	13.968	13.856	EPSD	ICGC;COSMIC	11.915	Down-regulation
CK1_CK1_CK1-D_CSNK1D_ST	P49810	PSEN2	P48730	CSNK1D	S9	L2F	2	Missense	distal	-7	no	13.968	14.588	EPSD	ICGC	11.915	Up-regulation
CK1_CK1_CK1-D_CSNK1D_ST	P49810	PSEN2	P48730	CSNK1D	T18	M21I	21	Missense	distal	3	no	13.520	11.074	EPSD	ICGC;COSMIC;GDSC;CCLE	11.915	Loss
CK1_CK1_CK1-D_CSNK1D_ST	P49810	PSEN2	P48730	CSNK1D	S19	M21I	21	Missense	proximal	2	no	14.760	16.355	EPSD	ICGC;COSMIC;GDSC;CCLE	11.915	Up-regulation
CK1_CK1_CK1-D_CSNK1D_ST	P49810	PSEN2	P48730	CSNK1D	T27	M21I	21	Missense	distal	-6	no	15.278	15.299	EPSD	ICGC;COSMIC;GDSC;CCLE	11.915	Up-regulation
CK1_CK1_CK1-D_CSNK1D_ST	P49810	PSEN2	P48730	CSNK1D	S327	G332W	332	Missense	distal	5	no	18.777	17.405	EPSD;PhosphoSitePlus	ICGC;COSMIC	11.915	Down-regulation
CK1_CK1_CK1-D_CSNK1D_ST	P49810	PSEN2	P48730	CSNK1D	S327	E322G	322	Missense	distal	-5	no	18.777	17.963	EPSD;PhosphoSitePlus	ICGC	11.915	Down-regulation
CK1_CK1_CK1-D_CSNK1D_ST	P49810	PSEN2	P48730	CSNK1D	S327	P321Q	321	Missense	distal	-6	no	18.777	19.856	EPSD;PhosphoSitePlus	ICGC;COSMIC	11.915	Up-regulation
CK1_CK1_CK1-D_CSNK1D_ST	P49810	PSEN2	P48730	CSNK1D	S330	G332W	332	Missense	proximal	2	no	13.880	9.649	PhosphoSitePlus;EPSD	ICGC;COSMIC	11.915	Loss
CK1_CK1_CK1-D_CSNK1D_ST	P35222	CTNNB1	P48730	CSNK1D	T3	T3N	3	Missense	central	0	yes	15.968	0.000	EPSD	ICGC;COSMIC	11.915	Loss
CK1_CK1_CK1-D_CSNK1D_ST	P35222	CTNNB1	P48730	CSNK1D	T547	R542C	542	Missense	distal	-5	no	12.866	12.387	EPSD	ICGC;COSMIC	11.915	Down-regulation
CK1_CK1_CK1-D_CSNK1D_ST	Q14511	NEDD9	P48730	CSNK1D	S298	P303S	303	Missense	distal	5	no	12.728	12.866	EPSD	ICGC	11.915	Up-regulation
CK1_CK1_CK1-D_CSNK1D_ST	Q14511	NEDD9	P48730	CSNK1D	S298	P299L	299	Missense	proximal	1	no	12.728	12.679	EPSD	ICGC;COSMIC	11.915	Down-regulation
CK1_CK1_CK1-D_CSNK1D_ST	Q14511	NEDD9	P48730	CSNK1D	S298	P302Q	302	Missense	distal	4	no	12.728	12.710	EPSD	ICGC;COSMIC	11.915	Down-regulation
CK1_CK1_CK1-D_CSNK1D_ST	Q14511	NEDD9	P48730	CSNK1D	S298	P302T	302	Missense	distal	4	no	12.728	12.701	EPSD	ICGC	11.915	Down-regulation
CK1_CK1_CK1-D_CSNK1D_ST	Q14511	NEDD9	P48730	CSNK1D	S298	S296R	296	Missense	proximal	-2	no	12.728	12.013	EPSD	ICGC	11.915	Down-regulation
CK1_CK1_CK1-D_CSNK1D_ST	Q14511	NEDD9	P48730	CSNK1D	S309	P303S	303	Missense	distal	-6	no	10.355	11.998	EPSD	ICGC	11.915	Gain
CK1_CK1_CK1-D_CSNK1D_ST	Q14511	NEDD9	P48730	CSNK1D	S395	R401T	401	Missense	distal	6	no	14.119	14.127	EPSD	ICGC;COSMIC	11.915	Up-regulation
CK1_CK1_CK1-D_CSNK1D_ST	Q14511	NEDD9	P48730	CSNK1D	S395	L392M	392	Missense	distal	-3	no	14.119	14.387	EPSD	ICGC	11.915	Up-regulation
CK1_CK1_CK1-D_CSNK1D_ST	Q14511	NEDD9	P48730	CSNK1D	S395	D399E	399	Missense	distal	4	no	14.119	13.496	EPSD	ICGC	11.915	Down-regulation
CK1_CK1_CK1-D_CSNK1D_ST	Q14511	NEDD9	P48730	CSNK1D	S618	D619H	619	Missense	proximal	1	no	14.820	15.651	EPSD	ICGC	11.915	Up-regulation
CK1_CK1_CK1-D_CSNK1D_ST	Q14511	NEDD9	P48730	CSNK1D	S618	S617R	617	Missense	proximal	-1	no	14.820	14.602	EPSD	ICGC	11.915	Down-regulation
CK1_CK1_CK1-D_CSNK1D_ST	Q14511	NEDD9	P48730	CSNK1D	S621	D619H	619	Missense	proximal	-2	no	13.835	14.557	EPSD	ICGC	11.915	Up-regulation
CK1_CK1_CK1-D_CSNK1D_ST	Q14511	NEDD9	P48730	CSNK1D	S621	S617R	617	Missense	distal	-4	no	13.835	13.327	EPSD	ICGC	11.915	Down-regulation
CK1_CK1_CK1-D_CSNK1D_ST	Q14511	NEDD9	P48730	CSNK1D	T804	A798T	798	Missense	distal	-6	no	15.147	13.771	EPSD;PhosphoSitePlus	ICGC;COSMIC;GDSC	11.915	Down-regulation
CK1_CK1_CK1-D_CSNK1D_ST	P46937	YAP1	P48730	CSNK1D	T119	V123F	123	Missense	distal	4	no	13.730	13.072	EPSD	ICGC	11.915	Down-regulation
CK1_CK1_CK1-D_CSNK1D_ST	P46937	YAP1	P48730	CSNK1D	T119	A117S	117	Missense	proximal	-2	no	13.730	12.464	EPSD	ICGC	11.915	Down-regulation
CK1_CK1_CK1-D_CSNK1D_ST	P46937	YAP1	P48730	CSNK1D	T119	A115T	115	Missense	distal	-4	no	13.730	13.033	EPSD	ICGC	11.915	Down-regulation
CK1_CK1_CK1-D_CSNK1D_ST	P46937	YAP1	P48730	CSNK1D	T119	H126R	126	Missense	distal	7	no	13.730	10.777	EPSD	ICGC;COSMIC	11.915	Loss
CK1_CK1_CK1-D_CSNK1D_ST	P46937	YAP1	P48730	CSNK1D	S274	A268P	268	Missense	distal	-6	no	12.283	10.482	EPSD	ICGC;COSMIC	11.915	Loss
CK1_CK1_CK1-D_CSNK1D_ST	P46937	YAP1	P48730	CSNK1D	S274	R272G	272	Missense	proximal	-2	no	12.283	13.602	EPSD	ICGC;COSMIC	11.915	Up-regulation
CK1_CK1_CK1-D_CSNK1D_ST	P46937	YAP1	P48730	CSNK1D	S300	S300P	300	Missense	central	0	yes	15.258	0.000	EPSD	ICGC;COSMIC	11.915	Loss
CK1_CK1_CK1-D_CSNK1D_ST	P46937	YAP1	P48730	CSNK1D	S400	L402P	402	Missense	proximal	2	no	16.819	17.724	EPSD	ICGC;COSMIC	11.915	Up-regulation
CK1_CK1_CK1-D_CSNK1D_ST	P46937	YAP1	P48730	CSNK1D	S400	R394Q	394	Missense	distal	-6	no	16.819	16.486	EPSD	ICGC;COSMIC	11.915	Down-regulation
CK1_CK1_CK1-D_CSNK1D_ST	P46937	YAP1	P48730	CSNK1D	S400	S397I	397	Missense	distal	-3	no	16.819	8.748	EPSD	ICGC	11.915	Loss
CK1_CK1_CK1-D_CSNK1D_ST	P46937	YAP1	P48730	CSNK1D	S400	T398A	398	Missense	proximal	-2	no	16.819	16.478	EPSD	ICGC;COSMIC	11.915	Down-regulation
CK1_CK1_CK1-D_CSNK1D_ST	P46937	YAP1	P48730	CSNK1D	S403	V409F	409	Missense	distal	6	no	11.881	14.071	EPSD	ICGC	11.915	Gain
CK1_CK1_CK1-D_CSNK1D_ST	P46937	YAP1	P48730	CSNK1D	S403	T398A	398	Missense	distal	-5	no	11.881	13.742	EPSD	ICGC;COSMIC	11.915	Gain
CK1_CK1_CK1-D_CSNK1D_ST	O43312	MTSS1	P48730	CSNK1D	S446	T443A	443	Missense	distal	-3	no	14.585	13.732	EPSD	ICGC;COSMIC	11.915	Down-regulation
CK1_CK1_CK1-D_CSNK1D_ST	O43312	MTSS1	P48730	CSNK1D	S446	A452T	452	Missense	distal	6	no	14.585	13.323	EPSD	ICGC	11.915	Down-regulation
CK1_CK1_CK1-D_CSNK1D_ST	P43629	KIR3DL1	P48730	CSNK1D	S385	T382K	382	Missense	distal	-3	no	15.402	13.790	EPSD;PhosphoSitePlus	ICGC	11.915	Down-regulation
CK1_CK1_CK1-D_CSNK1D_ST	P43629	KIR3DL1	P48730	CSNK1D	S385	T382R	382	Missense	distal	-3	no	15.402	15.897	EPSD;PhosphoSitePlus	ICGC	11.915	Up-regulation
CK1_CK1_CK1-D_CSNK1D_ST	P43629	KIR3DL1	P48730	CSNK1D	S385	G379A	379	Missense	distal	-6	no	15.402	16.209	EPSD;PhosphoSitePlus	ICGC	11.915	Up-regulation
CK1_CK1_CK1-D_CSNK1D_ST	P43629	KIR3DL1	P48730	CSNK1D	S385	Q391K	391	Missense	distal	6	no	15.402	15.358	EPSD;PhosphoSitePlus	ICGC;COSMIC	11.915	Down-regulation
CK1_CK1_CK1-D_CSNK1D_ST	P43629	KIR3DL1	P48730	CSNK1D	S385	N384D	384	Missense	proximal	-1	no	15.402	15.404	EPSD;PhosphoSitePlus	ICGC	11.915	Up-regulation
CK1_CK1_CK1-D_CSNK1D_ST	P43629	KIR3DL1	P48730	CSNK1D	S385	R381K	381	Missense	distal	-4	no	15.402	15.658	EPSD;PhosphoSitePlus	ICGC	11.915	Up-regulation
CK1_CK1_CK1-D_CSNK1D_ST	P43629	KIR3DL1	P48730	CSNK1D	S385	G379W	379	Missense	distal	-6	no	15.402	14.292	EPSD;PhosphoSitePlus	ICGC	11.915	Down-regulation
CK1_CK1_CK1-D_CSNK1D_ST	P43629	KIR3DL1	P48730	CSNK1D	S388	T382K	382	Missense	distal	-6	no	19.910	20.586	PhosphoSitePlus;EPSD	ICGC	11.915	Up-regulation
CK1_CK1_CK1-D_CSNK1D_ST	P43629	KIR3DL1	P48730	CSNK1D	S388	T382R	382	Missense	distal	-6	no	19.910	20.897	PhosphoSitePlus;EPSD	ICGC	11.915	Up-regulation
CK1_CK1_CK1-D_CSNK1D_ST	P43629	KIR3DL1	P48730	CSNK1D	S388	Q391K	391	Missense	distal	3	no	19.910	19.991	PhosphoSitePlus;EPSD	ICGC;COSMIC	11.915	Up-regulation
CK1_CK1_CK1-D_CSNK1D_ST	P43629	KIR3DL1	P48730	CSNK1D	S388	N384D	384	Missense	distal	-4	no	19.910	19.916	PhosphoSitePlus;EPSD	ICGC	11.915	Up-regulation
CK1_CK1_CK1-D_CSNK1D_ST	P43629	KIR3DL1	P48730	CSNK1D	S388	R381K	381	Missense	distal	-7	no	19.910	20.113	PhosphoSitePlus;EPSD	ICGC	11.915	Up-regulation
CK1_CK1_CK1-D_CSNK1D_ST	Q9Y6Q9	NCOA3	P48730	CSNK1D	S551	L548W	548	Missense	distal	-3	no	13.774	12.981	EPSD	ICGC;COSMIC	11.915	Down-regulation
CK1_CK1_CK1-D_CSNK1D_ST	Q9Y6Q9	NCOA3	P48730	CSNK1D	S583	Q586H	586	Missense	distal	3	no	12.872	13.159	EPSD	ICGC;COSMIC	11.915	Up-regulation
CK1_CK1_CK1-D_CSNK1D_ST	Q9Y6Q9	NCOA3	P48730	CSNK1D	S583	D576Y	576	Missense	distal	-7	no	12.872	10.567	EPSD	ICGC;COSMIC	11.915	Loss
CK1_CK1_CK1-D_CSNK1D_ST	Q9Y6Q9	NCOA3	P48730	CSNK1D	S589	Q586H	586	Missense	distal	-3	no	13.105	14.607	EPSD	ICGC;COSMIC	11.915	Up-regulation
CK1_CK1_CK1-D_CSNK1D_ST	Q9Y6Q9	NCOA3	P48730	CSNK1D	S712	I713V	713	Missense	proximal	1	no	10.688	13.387	EPSD	ICGC;COSMIC	11.915	Gain
CK1_CK1_CK1-D_CSNK1D_ST	Q9Y6Q9	NCOA3	P48730	CSNK1D	S712	T714A	714	Missense	proximal	2	no	10.688	12.194	EPSD	ICGC	11.915	Gain
CK1_CK1_CK1-D_CSNK1D_ST	Q9Y6Q9	NCOA3	P48730	CSNK1D	S767	G761V	761	Missense	distal	-6	no	12.982	13.476	EPSD	ICGC;COSMIC	11.915	Up-regulation
CK1_CK1_CK1-D_CSNK1D_ST	P30291	WEE1	P48730	CSNK1D	S31	F27L	27	Missense	distal	-4	no	14.224	14.288	EPSD	ICGC;COSMIC	11.915	Up-regulation
CK1_CK1_CK1-D_CSNK1D_ST	P30291	WEE1	P48730	CSNK1D	S31	E35D	35	Missense	distal	4	no	14.224	14.847	EPSD	ICGC;COSMIC	11.915	Up-regulation
CK1_CK1_CK1-D_CSNK1D_ST	P30291	WEE1	P48730	CSNK1D	S45	E40G	40	Missense	distal	-5	no	16.502	15.688	EPSD	ICGC;COSMIC	11.915	Down-regulation
CK1_CK1_CK1-D_CSNK1D_ST	P30291	WEE1	P48730	CSNK1D	S123	A130V	130	Missense	distal	7	no	16.095	17.017	EPSD	ICGC;COSMIC	11.915	Up-regulation
CK1_CK1_CK1-D_CSNK1D_ST	P30291	WEE1	P48730	CSNK1D	S205	G210C	210	Missense	distal	5	no	11.505	11.933	EPSD	ICGC;COSMIC	11.915	Gain
CK1_CK1_CK1-D_CSNK1D_ST	P30291	WEE1	P48730	CSNK1D	S212	M215I	215	Missense	distal	3	no	17.521	15.075	PhosphoSitePlus	ICGC;COSMIC	11.915	Down-regulation
CK1_CK1_CK1-D_CSNK1D_ST	P30291	WEE1	P48730	CSNK1D	S212	G210C	210	Missense	proximal	-2	no	17.521	17.895	PhosphoSitePlus	ICGC;COSMIC	11.915	Up-regulation
CK1_CK1_CK1-D_CSNK1D_ST	P30291	WEE1	P48730	CSNK1D	S242	P240Q	240	Missense	proximal	-2	no	13.310	14.967	EPSD	ICGC;COSMIC	11.915	Up-regulation
CK1_CK1_CK1-D_CSNK1D_ST	P30291	WEE1	P48730	CSNK1D	S471	H466Y	466	Missense	distal	-5	no	11.499	12.281	EPSD	ICGC	11.915	Gain
CK1_CK1_CK1-D_CSNK1D_ST	P30291	WEE1	P48730	CSNK1D	S471	L464I	464	Missense	distal	-7	no	11.499	12.893	EPSD	ICGC	11.915	Gain
CK1_CK1_CK1-D_CSNK1D_ST	P30291	WEE1	P48730	CSNK1D	S559	A560S	560	Missense	proximal	1	no	13.064	13.500	EPSD	ICGC;COSMIC	11.915	Up-regulation
CK1_CK1_CK1-D_CSNK1D_ST	P30291	WEE1	P48730	CSNK1D	S592	E587K	587	Missense	distal	-5	no	12.215	10.637	EPSD	ICGC;COSMIC	11.915	Loss
CK1_CK1_CK1-D_CSNK1D_ST	Q16665	HIF1A	P48730	CSNK1D	S14	K10N	10	Missense	distal	-4	no	12.497	12.500	EPSD	ICGC;COSMIC	11.915	Up-regulation
CK1_CK1_CK1-D_CSNK1D_ST	Q16665	HIF1A	P48730	CSNK1D	S14	R18Q	18	Missense	distal	4	no	12.497	12.538	EPSD	ICGC;COSMIC	11.915	Up-regulation
CK1_CK1_CK1-D_CSNK1D_ST	Q16665	HIF1A	P48730	CSNK1D	S14	R17G	17	Missense	distal	3	no	12.497	14.818	EPSD	ICGC;COSMIC	11.915	Up-regulation
CK1_CK1_CK1-D_CSNK1D_ST	Q16665	HIF1A	P48730	CSNK1D	S14	K19Q	19	Missense	distal	5	no	12.497	11.910	EPSD	ICGC;COSMIC	11.915	Loss
CAMK_MAPKAPK_MNK_MKNK1_ST	P06730	EIF4E	Q9BUB5-2	MKNK1	S209	R214K	214	Missense	distal	5	no	11.229	11.265	PhosphoSitePlus	ICGC;COSMIC	8.316	Up-regulation
CAMK_MAPKAPK_MNK_MKNK1_ST	P06730	EIF4E	Q9BUB5-2	MKNK1	T210	R214K	214	Missense	distal	4	no	10.960	9.541	EPSD	ICGC;COSMIC	8.316	Down-regulation
Atypical_PDHK_PDHK_PDK4_ST	P29803	PDHA2	Q16654	PDK4	S128	S128Y	128	Missense	central	0	yes	2.424	0.000	EPSD	ICGC	1.272	Loss
Atypical_PDHK_PDHK_PDK4_ST	P29803	PDHA2	Q16654	PDK4	S128	L127R	127	Missense	proximal	-1	no	2.424	2.400	EPSD	ICGC;COSMIC	1.272	Down-regulation
Atypical_PDHK_PDHK_PDK4_ST	P29803	PDHA2	Q16654	PDK4	S128	R125L	125	Missense	distal	-3	no	2.424	2.384	EPSD	ICGC;COSMIC	1.272	Down-regulation
Atypical_PDHK_PDHK_PDK4_ST	P29803	PDHA2	Q16654	PDK4	T284	R286C	286	Missense	proximal	2	no	2.392	2.233	EPSD	ICGC;COSMIC	1.272	Down-regulation
Atypical_PDHK_PDHK_PDK4_ST	P29803	PDHA2	Q16654	PDK4	T284	P277R	277	Missense	distal	-7	no	2.392	2.327	EPSD	ICGC;COSMIC	1.272	Down-regulation
Atypical_PDHK_PDHK_PDK4_ST	P29803	PDHA2	Q16654	PDK4	T284	R286S	286	Missense	proximal	2	no	2.392	2.299	EPSD	ICGC;COSMIC	1.272	Down-regulation
Atypical_PDHK_PDHK_PDK4_ST	P29803	PDHA2	Q16654	PDK4	S291	R286C	286	Missense	distal	-5	no	13.830	13.386	EPSD;PhosphoSitePlus	ICGC;COSMIC	1.272	Down-regulation
Atypical_PDHK_PDHK_PDK4_ST	P29803	PDHA2	Q16654	PDK4	S291	R286S	286	Missense	distal	-5	no	13.830	13.570	EPSD;PhosphoSitePlus	ICGC;COSMIC	1.272	Down-regulation
Other_PLK_SAK_PLK4_ST	O00444	PLK4	O00444	PLK4	S22	G25C	25	Missense	distal	3	no	540.424	473.685	PhosphoSitePlus;EPSD	ICGC	416.076	Down-regulation
Other_PLK_SAK_PLK4_ST	O00444	PLK4	O00444	PLK4	S270	R267Q	267	Missense	distal	-3	no	525.521	518.142	EPSD	ICGC;COSMIC;GDSC	416.076	Down-regulation
Other_PLK_SAK_PLK4_ST	O00444	PLK4	O00444	PLK4	S305	D308G	308	Missense	distal	3	no	601.221	608.317	EPSD;PhosphoSitePlus	ICGC;COSMIC	416.076	Up-regulation
Other_PLK_SAK_PLK4_ST	O00444	PLK4	O00444	PLK4	S305	F307C	307	Missense	proximal	2	no	601.221	551.376	EPSD;PhosphoSitePlus	ICGC;COSMIC	416.076	Down-regulation
Other_PLK_SAK_PLK4_ST	O00444	PLK4	O00444	PLK4	S305	D308Y	308	Missense	distal	3	no	601.221	573.501	EPSD;PhosphoSitePlus	ICGC	416.076	Down-regulation
Other_PLK_SAK_PLK4_ST	P61160	ACTR2	O00444	PLK4	S66	S62I	62	Missense	distal	-4	no	424.516	330.002	EPSD	ICGC	416.076	Loss
Other_PLK_SAK_PLK4_ST	P61160	ACTR2	O00444	PLK4	T237	S243Y	243	Missense	distal	6	no	599.089	552.488	EPSD;PhosphoSitePlus	ICGC;COSMIC	416.076	Down-regulation
Other_PLK_SAK_PLK4_ST	P61160	ACTR2	O00444	PLK4	T237	T237I	237	Missense	central	0	yes	599.089	0.000	EPSD;PhosphoSitePlus	ICGC	416.076	Loss
Other_PLK_SAK_PLK4_ST	P61160	ACTR2	O00444	PLK4	T238	S243Y	243	Missense	distal	5	no	502.382	503.852	PhosphoSitePlus;EPSD	ICGC;COSMIC	416.076	Up-regulation
Other_PLK_SAK_PLK4_ST	P61160	ACTR2	O00444	PLK4	T238	T237I	237	Missense	proximal	-1	no	502.382	490.107	PhosphoSitePlus;EPSD	ICGC	416.076	Down-regulation
Other_PLK_SAK_PLK4_ST	P61160	ACTR2	O00444	PLK4	S304	V302A	302	Missense	proximal	-2	no	411.068	535.483	EPSD	ICGC;COSMIC	416.076	Gain
Other_PLK_SAK_PLK4_ST	P61160	ACTR2	O00444	PLK4	S304	P311S	311	Missense	distal	7	no	411.068	430.415	EPSD	ICGC;COSMIC	416.076	Gain
Other_PLK_SAK_PLK4_ST	P61160	ACTR2	O00444	PLK4	S304	P311T	311	Missense	distal	7	no	411.068	431.978	EPSD	ICGC	416.076	Gain
Other_PLK_SAK_PLK4_ST	Q9HC77	CENPJ	O00444	PLK4	S471	P470L	470	Missense	proximal	-1	no	403.155	422.083	EPSD	ICGC	416.076	Gain
Other_PLK_SAK_PLK4_ST	Q9HC77	CENPJ	O00444	PLK4	S529	P527S	527	Missense	proximal	-2	no	302.255	428.667	EPSD	ICGC	416.076	Gain
Other_PLK_SAK_PLK4_ST	Q9HC77	CENPJ	O00444	PLK4	S540	P541L	541	Missense	proximal	1	no	231.667	464.604	EPSD	ICGC;COSMIC	416.076	Gain
Other_PLK_SAK_PLK4_ST	Q9HC77	CENPJ	O00444	PLK4	T545	P541L	541	Missense	distal	-4	no	437.865	511.092	EPSD	ICGC;COSMIC	416.076	Up-regulation
Other_PLK_SAK_PLK4_ST	Q9HC77	CENPJ	O00444	PLK4	T545	T545A	545	Missense	central	0	yes	437.865	0.000	EPSD	ICGC;COSMIC	416.076	Loss
Other_PLK_SAK_PLK4_ST	Q9HC77	CENPJ	O00444	PLK4	S660	A654T	654	Missense	distal	-6	no	472.220	464.944	EPSD	ICGC;COSMIC	416.076	Down-regulation
Other_PLK_SAK_PLK4_ST	Q9HC77	CENPJ	O00444	PLK4	S660	Q657K	657	Missense	distal	-3	no	472.220	470.864	EPSD	ICGC	416.076	Down-regulation
Other_PLK_SAK_PLK4_ST	Q9HC77	CENPJ	O00444	PLK4	S660	A654V	654	Missense	distal	-6	no	472.220	450.835	EPSD	ICGC;COSMIC	416.076	Down-regulation
Other_PLK_SAK_PLK4_ST	Q9HC77	CENPJ	O00444	PLK4	S662	Q657K	657	Missense	distal	-5	no	423.146	422.978	EPSD	ICGC	416.076	Down-regulation
Other_PLK_SAK_PLK4_ST	Q9HC77	CENPJ	O00444	PLK4	S717	P716L	716	Missense	proximal	-1	no	401.231	420.159	EPSD	ICGC	416.076	Gain
Other_PLK_SAK_PLK4_ST	Q9HC77	CENPJ	O00444	PLK4	S1125	P1126L	1126	Missense	proximal	1	no	331.902	564.839	EPSD	ICGC	416.076	Gain
Other_PLK_SAK_PLK4_ST	Q969U6	FBXW5	O00444	PLK4	S151	D149N	149	Missense	proximal	-2	no	614.676	666.930	PhosphoSitePlus	ICGC	416.076	Up-regulation
Other_PLK_SAK_PLK4_ST	Q15154	PCM1	O00444	PLK4	S370	R375S	375	Missense	distal	5	no	467.069	469.353	EPSD	ICGC;COSMIC	416.076	Up-regulation
Other_PLK_SAK_PLK4_ST	Q15154	PCM1	O00444	PLK4	S370	T374N	374	Missense	distal	4	no	467.069	445.684	EPSD	ICGC;COSMIC	416.076	Down-regulation
Other_PLK_SAK_PLK4_ST	Q15154	PCM1	O00444	PLK4	S372	R375S	375	Missense	distal	3	no	751.413	778.422	PhosphoSitePlus	ICGC;COSMIC	416.076	Up-regulation
Other_PLK_SAK_PLK4_ST	Q15154	PCM1	O00444	PLK4	S372	T374N	374	Missense	proximal	2	no	751.413	709.293	PhosphoSitePlus	ICGC;COSMIC	416.076	Down-regulation
Other_PLK_SAK_PLK4_ST	Q15154	PCM1	O00444	PLK4	T441	V436F	436	Missense	distal	-5	no	416.129	416.252	EPSD	ICGC;COSMIC	416.076	Up-regulation
Other_PLK_SAK_PLK4_ST	Q15154	PCM1	O00444	PLK4	T441	S442P	442	Missense	proximal	1	no	416.129	271.562	EPSD	ICGC	416.076	Loss
Other_PLK_SAK_PLK4_ST	Q15154	PCM1	O00444	PLK4	T441	Q438K	438	Missense	distal	-3	no	416.129	414.774	EPSD	ICGC;COSMIC	416.076	Loss
Other_PLK_SAK_PLK4_ST	Q15154	PCM1	O00444	PLK4	T441	R439K	439	Missense	proximal	-2	no	416.129	349.223	EPSD	ICGC;COSMIC	416.076	Loss
Other_PLK_SAK_PLK4_ST	Q15154	PCM1	O00444	PLK4	S471	Q475H	475	Missense	distal	4	no	426.015	430.153	EPSD	ICGC	416.076	Up-regulation
Other_PLK_SAK_PLK4_ST	Q15154	PCM1	O00444	PLK4	S471	V465F	465	Missense	distal	-6	no	426.015	416.336	EPSD	ICGC	416.076	Down-regulation
Other_PLK_SAK_PLK4_ST	Q15154	PCM1	O00444	PLK4	S471	L472I	472	Missense	proximal	1	no	426.015	382.425	EPSD	ICGC;COSMIC	416.076	Loss
Other_PLK_SAK_PLK4_ST	Q15154	PCM1	O00444	PLK4	S588	A589T	589	Missense	proximal	1	no	513.967	566.705	EPSD	ICGC;COSMIC	416.076	Up-regulation
Other_PLK_SAK_PLK4_ST	Q15154	PCM1	O00444	PLK4	S588	I592K	592	Missense	distal	4	no	513.967	529.178	EPSD	ICGC;COSMIC	416.076	Up-regulation
Other_PLK_SAK_PLK4_ST	Q15154	PCM1	O00444	PLK4	S637	S643N	643	Missense	distal	6	no	442.163	420.422	EPSD	ICGC;COSMIC	416.076	Down-regulation
Other_PLK_SAK_PLK4_ST	Q15154	PCM1	O00444	PLK4	S639	S643N	643	Missense	distal	4	no	450.315	439.063	EPSD	ICGC;COSMIC	416.076	Down-regulation
Other_PLK_SAK_PLK4_ST	Q15154	PCM1	O00444	PLK4	S690	A691S	691	Missense	proximal	1	no	425.538	386.265	EPSD	ICGC;COSMIC	416.076	Loss
Other_PLK_SAK_PLK4_ST	Q15154	PCM1	O00444	PLK4	S694	A691S	691	Missense	distal	-3	no	449.069	446.859	EPSD	ICGC;COSMIC	416.076	Down-regulation
Other_PLK_SAK_PLK4_ST	Q15154	PCM1	O00444	PLK4	S694	P701Q	701	Missense	distal	7	no	449.069	455.103	EPSD	ICGC;COSMIC	416.076	Up-regulation
Other_PLK_SAK_PLK4_ST	Q15154	PCM1	O00444	PLK4	S866	D870G	870	Missense	distal	4	no	445.019	449.370	EPSD	ICGC;COSMIC	416.076	Up-regulation
Other_PLK_SAK_PLK4_ST	Q15154	PCM1	O00444	PLK4	S869	D870G	870	Missense	proximal	1	no	403.163	439.996	EPSD	ICGC;COSMIC	416.076	Gain
Other_PLK_SAK_PLK4_ST	Q15154	PCM1	O00444	PLK4	T1451	W1452L	1452	Missense	proximal	1	no	289.496	441.372	EPSD	ICGC	416.076	Gain
Other_PLK_SAK_PLK4_ST	Q15154	PCM1	O00444	PLK4	S1462	E1463G	1463	Missense	proximal	1	no	419.235	440.228	EPSD	ICGC;COSMIC	416.076	Up-regulation
Other_PLK_SAK_PLK4_ST	Q15154	PCM1	O00444	PLK4	S1462	A1466S	1466	Missense	distal	4	no	419.235	422.598	EPSD	ICGC	416.076	Up-regulation
Other_PLK_SAK_PLK4_ST	Q15154	PCM1	O00444	PLK4	S1462	S1464I	1464	Missense	proximal	2	no	419.235	413.400	EPSD	ICGC;COSMIC	416.076	Loss
Other_PLK_SAK_PLK4_ST	Q15154	PCM1	O00444	PLK4	S1464	E1463G	1463	Missense	proximal	-1	no	480.026	478.198	EPSD	ICGC;COSMIC	416.076	Down-regulation
Other_PLK_SAK_PLK4_ST	Q15154	PCM1	O00444	PLK4	S1464	A1466S	1466	Missense	proximal	2	no	480.026	445.948	EPSD	ICGC	416.076	Down-regulation
Other_PLK_SAK_PLK4_ST	Q15154	PCM1	O00444	PLK4	S1464	S1464I	1464	Missense	central	0	yes	480.026	0.000	EPSD	ICGC;COSMIC	416.076	Loss
Other_PLK_SAK_PLK4_ST	Q15154	PCM1	O00444	PLK4	T1468	E1463G	1463	Missense	distal	-5	no	502.854	502.923	EPSD	ICGC;COSMIC	416.076	Up-regulation
Other_PLK_SAK_PLK4_ST	Q15154	PCM1	O00444	PLK4	T1468	A1466S	1466	Missense	proximal	-2	no	502.854	458.532	EPSD	ICGC	416.076	Down-regulation
Other_PLK_SAK_PLK4_ST	Q15154	PCM1	O00444	PLK4	T1468	S1464I	1464	Missense	distal	-4	no	502.854	408.340	EPSD	ICGC;COSMIC	416.076	Loss
Other_PLK_SAK_PLK4_ST	Q15154	PCM1	O00444	PLK4	T1472	E1478A	1478	Missense	distal	6	no	402.411	465.502	EPSD	ICGC;COSMIC	416.076	Gain
Other_PLK_SAK_PLK4_ST	Q15154	PCM1	O00444	PLK4	S1697	C1704F	1704	Missense	distal	7	no	422.117	436.087	EPSD	ICGC	416.076	Up-regulation
Other_PLK_SAK_PLK4_ST	Q15154	PCM1	O00444	PLK4	S1931	P1928T	1928	Missense	distal	-3	no	563.903	591.598	EPSD	ICGC;COSMIC	416.076	Up-regulation
Other_PLK_SAK_PLK4_ST	Q15468	STIL	O00444	PLK4	T557	P552H	552	Missense	distal	-5	no	444.543	444.129	EPSD	ICGC	416.076	Down-regulation
Other_PLK_SAK_PLK4_ST	O43303	CCP110	O00444	PLK4	S247	I252M	252	Missense	distal	5	no	464.522	464.098	EPSD	ICGC;COSMIC	416.076	Down-regulation
Other_PLK_SAK_PLK4_ST	O43303	CCP110	O00444	PLK4	S356	N351D	351	Missense	distal	-5	no	458.797	458.869	EPSD	ICGC	416.076	Up-regulation
Other_PLK_SAK_PLK4_ST	O43303	CCP110	O00444	PLK4	S356	G359C	359	Missense	distal	3	no	458.797	392.058	EPSD	ICGC;COSMIC	416.076	Loss
Other_PLK_SAK_PLK4_ST	O43303	CCP110	O00444	PLK4	T358	N351D	351	Missense	distal	-7	no	487.503	482.244	EPSD	ICGC	416.076	Down-regulation
Other_PLK_SAK_PLK4_ST	O43303	CCP110	O00444	PLK4	T358	P365H	365	Missense	distal	7	no	487.503	496.934	EPSD	ICGC;COSMIC	416.076	Up-regulation
Other_PLK_SAK_PLK4_ST	O43303	CCP110	O00444	PLK4	T358	G359C	359	Missense	proximal	1	no	487.503	351.716	EPSD	ICGC;COSMIC	416.076	Loss
Other_PLK_SAK_PLK4_ST	O43303	CCP110	O00444	PLK4	T382	M375I	375	Missense	distal	-7	no	478.780	474.379	EPSD	ICGC;COSMIC	416.076	Down-regulation
Other_PLK_SAK_PLK4_ST	O43303	CCP110	O00444	PLK4	T382	M375V	375	Missense	distal	-7	no	478.780	469.508	EPSD	ICGC;COSMIC	416.076	Down-regulation
Other_PLK_SAK_PLK4_ST	O43303	CCP110	O00444	PLK4	S668	Q674H	674	Missense	distal	6	no	390.544	422.142	EPSD	ICGC	416.076	Gain
AGC_DMPK_CRIK_CIT_ST	P24844	MYL9	O14578	CIT	T11	R17L	17	Missense	distal	6	no	0.458	0.476	EPSD	ICGC;COSMIC	0.226	Up-regulation
AGC_DMPK_CRIK_CIT_ST	P24844	MYL9	O14578	CIT	T11	R5Q	5	Missense	distal	-6	no	0.458	0.262	EPSD	ICGC;COSMIC	0.226	Down-regulation
AGC_DMPK_CRIK_CIT_ST	P24844	MYL9	O14578	CIT	T11	R14W	14	Missense	distal	3	no	0.458	0.519	EPSD	ICGC;COSMIC	0.226	Up-regulation
AGC_DMPK_CRIK_CIT_ST	P24844	MYL9	O14578	CIT	T19	R17L	17	Missense	proximal	-2	no	6.379	6.336	PhosphoSitePlus;EPSD	ICGC;COSMIC	0.226	Down-regulation
AGC_DMPK_CRIK_CIT_ST	P24844	MYL9	O14578	CIT	T19	R14W	14	Missense	distal	-5	no	6.379	6.341	PhosphoSitePlus;EPSD	ICGC;COSMIC	0.226	Down-regulation
AGC_DMPK_CRIK_CIT_ST	P24844	MYL9	O14578	CIT	S20	R17L	17	Missense	distal	-3	no	6.070	6.046	EPSD;PhosphoSitePlus	ICGC;COSMIC	0.226	Down-regulation
AGC_DMPK_CRIK_CIT_ST	P24844	MYL9	O14578	CIT	S20	R14W	14	Missense	distal	-6	no	6.070	5.897	EPSD;PhosphoSitePlus	ICGC;COSMIC	0.226	Down-regulation
Other_Aur_AURKC_ST	Q9NQS7	INCENP	Q9UQB9	AURKC	S61	R66W	66	Missense	distal	5	no	18.509	18.539	EPSD	ICGC;COSMIC	14.093	Up-regulation
Other_Aur_AURKC_ST	Q9NQS7	INCENP	Q9UQB9	AURKC	S61	R66Q	66	Missense	distal	5	no	18.509	18.541	EPSD	ICGC;COSMIC	14.093	Up-regulation
Other_Aur_AURKC_ST	Q9NQS7	INCENP	Q9UQB9	AURKC	S61	K63N	63	Missense	proximal	2	no	18.509	18.525	EPSD	ICGC	14.093	Up-regulation
Other_Aur_AURKC_ST	Q9NQS7	INCENP	Q9UQB9	AURKC	S72	R66W	66	Missense	distal	-6	no	20.122	20.158	EPSD	ICGC;COSMIC	14.093	Up-regulation
Other_Aur_AURKC_ST	Q9NQS7	INCENP	Q9UQB9	AURKC	S72	R66Q	66	Missense	distal	-6	no	20.122	20.300	EPSD	ICGC;COSMIC	14.093	Up-regulation
Other_Aur_AURKC_ST	Q9NQS7	INCENP	Q9UQB9	AURKC	S91	S98C	98	Missense	distal	7	no	19.994	20.257	EPSD	ICGC	14.093	Up-regulation
Other_Aur_AURKC_ST	Q9NQS7	INCENP	Q9UQB9	AURKC	S94	S98C	98	Missense	distal	4	no	18.704	17.780	EPSD	ICGC	14.093	Down-regulation
Other_Aur_AURKC_ST	Q9NQS7	INCENP	Q9UQB9	AURKC	S94	R100C	100	Missense	distal	6	no	18.704	18.181	EPSD	ICGC;COSMIC	14.093	Down-regulation
Other_Aur_AURKC_ST	Q9NQS7	INCENP	Q9UQB9	AURKC	S142	A137S	137	Missense	distal	-5	no	14.841	15.177	EPSD	ICGC	14.093	Up-regulation
Other_Aur_AURKC_ST	Q9NQS7	INCENP	Q9UQB9	AURKC	T207	S208Y	208	Missense	proximal	1	no	17.060	15.393	EPSD	ICGC;COSMIC	14.093	Down-regulation
Other_Aur_AURKC_ST	Q9NQS7	INCENP	Q9UQB9	AURKC	S234	L228M	228	Missense	distal	-6	no	20.731	20.434	EPSD	ICGC;COSMIC	14.093	Down-regulation
Other_Aur_AURKC_ST	Q9NQS7	INCENP	Q9UQB9	AURKC	S269	D274Y	274	Missense	distal	5	no	15.126	15.067	EPSD	ICGC	14.093	Down-regulation
Other_Aur_AURKC_ST	Q9NQS7	INCENP	Q9UQB9	AURKC	S269	G265D	265	Missense	distal	-4	no	15.126	15.363	EPSD	ICGC;COSMIC	14.093	Up-regulation
Other_Aur_AURKC_ST	Q9NQS7	INCENP	Q9UQB9	AURKC	S269	S275F	275	Missense	distal	6	no	15.126	12.711	EPSD	ICGC	14.093	Loss
Other_Aur_AURKC_ST	Q9NQS7	INCENP	Q9UQB9	AURKC	S269	D268G	268	Missense	proximal	-1	no	15.126	14.694	EPSD	ICGC;COSMIC	14.093	Down-regulation
Other_Aur_AURKC_ST	Q9NQS7	INCENP	Q9UQB9	AURKC	S306	S302L	302	Missense	distal	-4	no	18.471	18.998	EPSD	ICGC;COSMIC	14.093	Up-regulation
Other_Aur_AURKC_ST	Q9NQS7	INCENP	Q9UQB9	AURKC	S306	R304W	304	Missense	proximal	-2	no	18.471	11.421	EPSD	ICGC;COSMIC;GDSC	14.093	Loss
Other_Aur_AURKC_ST	Q9NQS7	INCENP	Q9UQB9	AURKC	S306	R304Q	304	Missense	proximal	-2	no	18.471	10.091	EPSD	ICGC;COSMIC	14.093	Loss
Other_Aur_AURKC_ST	Q9NQS7	INCENP	Q9UQB9	AURKC	S306	R304L	304	Missense	proximal	-2	no	18.471	7.166	EPSD	ICGC;COSMIC	14.093	Loss
Other_Aur_AURKC_ST	Q9NQS7	INCENP	Q9UQB9	AURKC	S323	Y322H	322	Missense	proximal	-1	no	13.268	14.329	EPSD	ICGC;COSMIC	14.093	Gain
Other_Aur_AURKC_ST	Q9NQS7	INCENP	Q9UQB9	AURKC	S336	A340S	340	Missense	distal	4	no	18.620	19.566	EPSD	ICGC;COSMIC	14.093	Up-regulation
Other_Aur_AURKC_ST	Q9NQS7	INCENP	Q9UQB9	AURKC	S336	R338M	338	Missense	proximal	2	no	18.620	18.425	EPSD	ICGC	14.093	Down-regulation
Other_Aur_AURKC_ST	Q9NQS7	INCENP	Q9UQB9	AURKC	S421	A427T	427	Missense	distal	6	no	16.139	16.167	EPSD	ICGC	14.093	Up-regulation
Other_Aur_AURKC_ST	Q9NQS7	INCENP	Q9UQB9	AURKC	S421	T424K	424	Missense	distal	3	no	16.139	16.113	EPSD	ICGC;COSMIC	14.093	Down-regulation
Other_Aur_AURKC_ST	Q9NQS7	INCENP	Q9UQB9	AURKC	S421	P422Q	422	Missense	proximal	1	no	16.139	16.659	EPSD	ICGC;COSMIC	14.093	Up-regulation
Other_Aur_AURKC_ST	Q9NQS7	INCENP	Q9UQB9	AURKC	S426	T424K	424	Missense	proximal	-2	no	12.357	14.628	EPSD	ICGC;COSMIC	14.093	Gain
Other_Aur_AURKC_ST	Q9NQS7	INCENP	Q9UQB9	AURKC	S486	P484T	484	Missense	proximal	-2	no	15.849	19.779	EPSD	ICGC;COSMIC	14.093	Up-regulation
Other_Aur_AURKC_ST	Q9NQS7	INCENP	Q9UQB9	AURKC	T509	M506T	506	Missense	distal	-3	no	13.440	14.549	EPSD	ICGC;COSMIC	14.093	Gain
Other_Aur_AURKC_ST	O15392	BIRC5	Q9UQB9	AURKC	S20	K23N	23	Missense	distal	3	no	28.038	28.302	PhosphoSitePlus	ICGC;COSMIC;GDSC;CCLE	14.093	Up-regulation
Other_Aur_AURKC_ST	O15392	BIRC5	Q9UQB9	AURKC	T34	P35T	35	Missense	proximal	1	no	12.779	14.953	EPSD	ICGC;COSMIC	14.093	Gain
Other_Aur_AURKC_ST	O15392	BIRC5	Q9UQB9	AURKC	S82	E75Q	75	Missense	distal	-7	no	14.197	13.986	EPSD	ICGC;COSMIC	14.093	Loss
Other_Aur_AURKC_ST	O15392	BIRC5	Q9UQB9	AURKC	S82	C84S	84	Missense	proximal	2	no	14.197	13.786	EPSD	ICGC;COSMIC	14.093	Loss
Other_Aur_AURKC_ST	O15392	BIRC5	Q9UQB9	AURKC	T117	E116K	116	Missense	proximal	-1	no	16.936	19.786	EPSD	ICGC;COSMIC	14.093	Up-regulation
Other_Aur_AURKC_ST	O15392	BIRC5	Q9UQB9	AURKC	T117	K110N	110	Missense	distal	-7	no	16.936	17.233	EPSD	ICGC;COSMIC	14.093	Up-regulation
Other_Aur_AURKC_ST	O75410	TACC1	Q9UQB9	AURKC	S91	L84F	84	Missense	distal	-7	no	15.108	14.886	EPSD	ICGC;COSMIC	14.093	Down-regulation
Other_Aur_AURKC_ST	O75410	TACC1	Q9UQB9	AURKC	S91	D98Y	98	Missense	distal	7	no	15.108	14.964	EPSD	ICGC;COSMIC	14.093	Down-regulation
Other_Aur_AURKC_ST	O75410	TACC1	Q9UQB9	AURKC	T250	N251S	251	Missense	proximal	1	no	13.237	14.718	EPSD	ICGC;COSMIC	14.093	Gain
Other_Aur_AURKC_ST	O75410	TACC1	Q9UQB9	AURKC	S299	G296C	296	Missense	distal	-3	no	14.024	14.290	EPSD	ICGC;COSMIC	14.093	Gain
Other_Aur_AURKC_ST	O75410	TACC1	Q9UQB9	AURKC	T302	G296C	296	Missense	distal	-6	no	14.145	13.951	EPSD	ICGC;COSMIC	14.093	Loss
Other_Aur_AURKC_ST	O75410	TACC1	Q9UQB9	AURKC	S315	E321Q	321	Missense	distal	6	no	14.898	14.183	EPSD	ICGC	14.093	Down-regulation
Other_Aur_AURKC_ST	O75410	TACC1	Q9UQB9	AURKC	S315	L320R	320	Missense	distal	5	no	14.898	14.823	EPSD	ICGC;COSMIC	14.093	Down-regulation
Other_Aur_AURKC_ST	O75410	TACC1	Q9UQB9	AURKC	S315	R314Q	314	Missense	proximal	-1	no	14.898	13.152	EPSD	ICGC	14.093	Loss
Other_Aur_AURKC_ST	O75410	TACC1	Q9UQB9	AURKC	S361	Q366H	366	Missense	distal	5	no	14.188	14.116	EPSD	ICGC	14.093	Down-regulation
Other_Aur_AURKC_ST	O75410	TACC1	Q9UQB9	AURKC	S361	K360N	360	Missense	proximal	-1	no	14.188	12.275	EPSD	ICGC	14.093	Loss
Other_Aur_AURKC_ST	O75410	TACC1	Q9UQB9	AURKC	T504	E506D	506	Missense	proximal	2	no	14.606	15.159	EPSD	ICGC	14.093	Up-regulation
Other_Aur_AURKC_ST	P25963	NFKBIA	Q9UQB9	AURKC	S32	R29S	29	Missense	distal	-3	no	31.679	30.782	PhosphoSitePlus	ICGC	14.093	Down-regulation
Other_Aur_AURKC_ST	P25963	NFKBIA	Q9UQB9	AURKC	S32	D31G	31	Missense	proximal	-1	no	31.679	31.247	PhosphoSitePlus	ICGC;COSMIC	14.093	Down-regulation
Other_Aur_AURKC_ST	P25963	NFKBIA	Q9UQB9	AURKC	S32	K38T	38	Missense	distal	6	no	31.679	29.720	PhosphoSitePlus	ICGC	14.093	Down-regulation
STE_STE7_MEK7_MAP2K7_ST	P45984	MAPK9	O14733	MAP2K7	T183	T188K	188	Missense	distal	5	no	8.801	7.328	EPSD;PhosphoSitePlus	ICGC	2.107	Down-regulation
STE_STE7_MEK7_MAP2K7_ST	P45984	MAPK9	O14733	MAP2K7	T183	V186M	186	Missense	distal	3	no	8.801	8.453	EPSD;PhosphoSitePlus	ICGC	2.107	Down-regulation
STE_STE7_MEK7_MAP2K7_ST	P45984	MAPK9	O14733	MAP2K7	T404	E402K	402	Missense	proximal	-2	no	6.076	6.048	EPSD;PhosphoSitePlus	ICGC;COSMIC	2.107	Down-regulation
STE_STE7_MEK7_MAP2K7_ST	P45984	MAPK9	O14733	MAP2K7	T404	D410E	410	Missense	distal	6	no	6.076	5.935	EPSD;PhosphoSitePlus	ICGC	2.107	Down-regulation
STE_STE7_MEK7_MAP2K7_ST	P45984	MAPK9	O14733	MAP2K7	T404	T409K	409	Missense	distal	5	no	6.076	4.603	EPSD;PhosphoSitePlus	ICGC	2.107	Down-regulation
STE_STE7_MEK7_MAP2K7_ST	P45984	MAPK9	O14733	MAP2K7	S407	E402K	402	Missense	distal	-5	no	5.531	5.524	PhosphoSitePlus;EPSD	ICGC;COSMIC	2.107	Down-regulation
STE_STE7_MEK7_MAP2K7_ST	P45984	MAPK9	O14733	MAP2K7	S407	D410E	410	Missense	distal	3	no	5.531	5.267	PhosphoSitePlus;EPSD	ICGC	2.107	Down-regulation
STE_STE7_MEK7_MAP2K7_ST	P45984	MAPK9	O14733	MAP2K7	S407	T409K	409	Missense	proximal	2	no	5.531	5.239	PhosphoSitePlus;EPSD	ICGC	2.107	Down-regulation
STE_STE7_MEK7_MAP2K7_ST	P45983	MAPK8	O14733	MAP2K7	T183	R189P	189	Missense	distal	6	no	9.246	9.259	PhosphoSitePlus;EPSD	ICGC;COSMIC	2.107	Up-regulation
STE_STE7_MEK7_MAP2K7_ST	P45983	MAPK8	O14733	MAP2K7	T183	S179I	179	Missense	distal	-4	no	9.246	8.642	PhosphoSitePlus;EPSD	ICGC	2.107	Down-regulation
STE_STE7_MEK7_MAP2K7_ST	P45983	MAPK8	O14733	MAP2K7	T183	T183M	183	Missense	central	0	yes	9.246	0.000	PhosphoSitePlus;EPSD	ICGC;COSMIC	2.107	Loss
STE_STE7_MEK7_MAP2K7_ST	Q13158	FADD	O14733	MAP2K7	T157	V162A	162	Missense	distal	5	no	2.998	3.238	EPSD	ICGC;COSMIC	2.107	Up-regulation
STE_STE7_MEK7_MAP2K7_ST	Q13158	FADD	O14733	MAP2K7	T157	A156T	156	Missense	proximal	-1	no	2.998	2.359	EPSD	ICGC;COSMIC	2.107	Down-regulation
STE_STE7_MEK7_MAP2K7_ST	Q13158	FADD	O14733	MAP2K7	T157	A164S	164	Missense	distal	7	no	2.998	2.940	EPSD	ICGC	2.107	Down-regulation
STE_STE7_MEK7_MAP2K7_ST	Q13158	FADD	O14733	MAP2K7	T157	T151I	151	Missense	distal	-6	no	2.998	3.293	EPSD	ICGC;COSMIC	2.107	Up-regulation
STE_STE7_MEK7_MAP2K7_ST	Q13158	FADD	O14733	MAP2K7	T157	G163V	163	Missense	distal	6	no	2.998	3.027	EPSD	ICGC;COSMIC	2.107	Up-regulation
STE_STE7_MEK7_MAP2K7_ST	Q13158	FADD	O14733	MAP2K7	T157	A159T	159	Missense	proximal	2	no	2.998	2.919	EPSD	ICGC	2.107	Down-regulation
STE_STE7_MEK7_MAP2K7_ST	Q13158	FADD	O14733	MAP2K7	S194	Q187H	187	Missense	distal	-7	no	5.970	5.923	PhosphoSitePlus	ICGC;COSMIC	2.107	Down-regulation
STE_STE7_MEK7_MAP2K7_ST	Q13158	FADD	O14733	MAP2K7	S194	S197T	197	Missense	distal	3	no	5.970	5.495	PhosphoSitePlus	ICGC	2.107	Down-regulation
STE_STE7_MEK7_MAP2K7_ST	Q13158	FADD	O14733	MAP2K7	S194	N199T	199	Missense	distal	5	no	5.970	6.661	PhosphoSitePlus	ICGC;COSMIC	2.107	Up-regulation
STE_STE7_MEK7_MAP2K7_ST	Q13158	FADD	O14733	MAP2K7	S197	T204A	204	Missense	distal	7	no	2.596	2.622	EPSD	ICGC;COSMIC	2.107	Up-regulation
STE_STE7_MEK7_MAP2K7_ST	Q13158	FADD	O14733	MAP2K7	S197	N199T	199	Missense	proximal	2	no	2.596	2.766	EPSD	ICGC;COSMIC	2.107	Up-regulation
TK_Src_Frk_FRK_Y	P60484	PTEN	P42685	FRK	Y155	L152R	152	Missense	distal	-3	no	2.445	3.096	EPSD	ICGC;COSMIC	2.774	Gain
TK_Src_Frk_FRK_Y	P60484	PTEN	P42685	FRK	Y336	D331N	331	Missense	distal	-5	no	10.404	10.402	PhosphoSitePlus	ICGC;COSMIC	2.774	Down-regulation
TK_Src_Frk_FRK_Y	P60484	PTEN	P42685	FRK	Y336	K330I	330	Missense	distal	-6	no	10.404	10.076	PhosphoSitePlus	ICGC;COSMIC	2.774	Down-regulation
TK_Src_Frk_FRK_Y	P60484	PTEN	P42685	FRK	Y336	R335G	335	Missense	proximal	-1	no	10.404	10.305	PhosphoSitePlus	ICGC;COSMIC	2.774	Down-regulation
Other_NAK_MPSK_STK16_ST	Q9Y295	DRG1	O75716	STK16	T100	A93S	93	Missense	distal	-7	no	3.396	3.397	EPSD	ICGC	1.527	Up-regulation
Other_NAK_MPSK_STK16_ST	Q9Y295	DRG1	O75716	STK16	T100	V105F	105	Missense	distal	5	no	3.396	3.313	EPSD	ICGC	1.527	Down-regulation
Other_NAK_MPSK_STK16_ST	Q9Y295	DRG1	O75716	STK16	T101	V105F	105	Missense	distal	4	no	3.377	3.404	PhosphoSitePlus	ICGC	1.527	Up-regulation
TK_EGFR_ERBB2_Y	O43157	PLXNB1	P04626	ERBB2	Y34	T33K	33	Missense	proximal	-1	no	2.762	2.917	EPSD	ICGC	2.878	Gain
TK_EGFR_ERBB2_Y	O43157	PLXNB1	P04626	ERBB2	Y1732	R1738S	1738	Missense	distal	6	no	5.600	5.181	EPSD;PhosphoSitePlus	ICGC;COSMIC	2.878	Down-regulation
TK_EGFR_ERBB2_Y	Q96N67	DOCK7	P04626	ERBB2	Y362	A368E	368	Missense	distal	6	no	2.332	2.986	EPSD	ICGC	2.878	Gain
TK_EGFR_ERBB2_Y	P06493	CDK1	P04626	ERBB2	Y15	T14A	14	Missense	proximal	-1	no	4.825	4.283	PhosphoSitePlus	ICGC;COSMIC	2.878	Down-regulation
AGC_DMPK_GEK_CDC42BPA_ST	Q5VT25	CDC42BPA	Q5VT25	CDC42BPA	S222	R216W	216	Missense	distal	-6	no	5.515	5.433	EPSD	ICGC;COSMIC	2.124	Down-regulation
AGC_DMPK_GEK_CDC42BPA_ST	Q5VT25	CDC42BPA	Q5VT25	CDC42BPA	S222	K225N	225	Missense	distal	3	no	5.515	5.456	EPSD	ICGC;COSMIC	2.124	Down-regulation
AGC_DMPK_GEK_CDC42BPA_ST	Q5VT25	CDC42BPA	Q5VT25	CDC42BPA	S234	S235L	235	Missense	proximal	1	no	5.474	5.364	EPSD;PhosphoSitePlus	ICGC;COSMIC	2.124	Down-regulation
AGC_DMPK_GEK_CDC42BPA_ST	Q5VT25	CDC42BPA	Q5VT25	CDC42BPA	S234	T231M	231	Missense	distal	-3	no	5.474	5.438	EPSD;PhosphoSitePlus	ICGC;COSMIC	2.124	Down-regulation
AGC_DMPK_GEK_CDC42BPA_ST	Q5VT25	CDC42BPA	Q5VT25	CDC42BPA	T240	S235L	235	Missense	distal	-5	no	5.481	5.664	EPSD;PhosphoSitePlus	ICGC;COSMIC	2.124	Up-regulation
AGC_DMPK_GEK_CDC42BPA_ST	Q5VT25	CDC42BPA	Q5VT25	CDC42BPA	T403	L410I	410	Missense	distal	7	no	5.559	5.468	PhosphoSitePlus;EPSD	ICGC	2.124	Down-regulation
AGC_DMPK_GEK_CDC42BPA_ST	Q5VT25	CDC42BPA	Q5VT25	CDC42BPA	S465	T466I	466	Missense	proximal	1	no	2.074	2.285	EPSD	ICGC;COSMIC	2.124	Gain
AGC_DMPK_GEK_CDC42BPA_ST	Q5VT25	CDC42BPA	Q5VT25	CDC42BPA	T482	L487S	487	Missense	distal	5	no	1.902	2.199	EPSD	ICGC	2.124	Gain
AGC_DMPK_GEK_CDC42BPA_ST	Q5VT25	CDC42BPA	Q5VT25	CDC42BPA	S1003	P1001S	1001	Missense	proximal	-2	no	5.520	4.689	EPSD;PhosphoSitePlus	ICGC	2.124	Down-regulation
AGC_DMPK_GEK_CDC42BPA_ST	Q5VT25	CDC42BPA	Q5VT25	CDC42BPA	S1627	S1632Y	1632	Missense	distal	5	no	2.178	2.032	EPSD	ICGC	2.124	Loss
AGC_DMPK_GEK_CDC42BPA_ST	Q5VT25	CDC42BPA	Q5VT25	CDC42BPA	S1627	S1627F	1627	Missense	central	0	yes	2.178	0.000	EPSD	ICGC	2.124	Loss
AGC_DMPK_GEK_CDC42BPA_ST	Q5VT25	CDC42BPA	Q5VT25	CDC42BPA	S1627	S1632A	1632	Missense	distal	5	no	2.178	2.146	EPSD	ICGC	2.124	Down-regulation
AGC_DMPK_GEK_CDC42BPA_ST	P24844	MYL9	Q5VT25	CDC42BPA	S20	R17L	17	Missense	distal	-3	no	5.235	5.239	PhosphoSitePlus	ICGC;COSMIC	2.124	Up-regulation
AGC_DMPK_GEK_CDC42BPA_ST	P24844	MYL9	Q5VT25	CDC42BPA	S20	R14W	14	Missense	distal	-6	no	5.235	5.152	PhosphoSitePlus	ICGC;COSMIC	2.124	Down-regulation
AGC_DMPK_GEK_CDC42BPA_ST	P24844	MYL9	Q5VT25	CDC42BPA	T97	E100K	100	Missense	distal	3	no	2.207	2.307	EPSD	ICGC;COSMIC	2.124	Up-regulation
AGC_DMPK_GEK_CDC42BPA_ST	P24844	MYL9	Q5VT25	CDC42BPA	T135	F134L	134	Missense	proximal	-1	no	2.231	2.059	EPSD	ICGC;COSMIC	2.124	Loss
STE_STE20_FRAY_OXSR1_ST	Q13621	SLC12A1	O95747	OXSR1	T95	G102C	102	Missense	distal	7	no	50.566	50.491	EPSD;PhosphoSitePlus	ICGC;COSMIC	17.710	Down-regulation
STE_STE20_FRAY_OXSR1_ST	Q13621	SLC12A1	O95747	OXSR1	T100	D107Y	107	Missense	distal	7	no	44.600	44.443	EPSD;PhosphoSitePlus	ICGC	17.710	Down-regulation
STE_STE20_FRAY_OXSR1_ST	Q13621	SLC12A1	O95747	OXSR1	T100	G102C	102	Missense	proximal	2	no	44.600	44.088	EPSD;PhosphoSitePlus	ICGC;COSMIC	17.710	Down-regulation
STE_STE20_FRAY_OXSR1_ST	Q13621	SLC12A1	O95747	OXSR1	T105	D107Y	107	Missense	proximal	2	no	50.424	52.836	PhosphoSitePlus;EPSD	ICGC	17.710	Up-regulation
STE_STE20_FRAY_OXSR1_ST	Q13621	SLC12A1	O95747	OXSR1	T105	G102C	102	Missense	distal	-3	no	50.424	49.935	PhosphoSitePlus;EPSD	ICGC;COSMIC	17.710	Down-regulation
STE_STE20_FRAY_OXSR1_ST	Q13621	SLC12A1	O95747	OXSR1	T118	E113D	113	Missense	distal	-5	no	46.996	45.933	EPSD;PhosphoSitePlus	ICGC	17.710	Down-regulation
STE_STE20_FRAY_OXSR1_ST	Q13621	SLC12A1	O95747	OXSR1	T118	S120I	120	Missense	proximal	2	no	46.996	43.526	EPSD;PhosphoSitePlus	ICGC	17.710	Down-regulation
STE_STE20_FRAY_OXSR1_ST	Q13621	SLC12A1	O95747	OXSR1	T118	P124T	124	Missense	distal	6	no	46.996	46.533	EPSD;PhosphoSitePlus	ICGC;COSMIC	17.710	Down-regulation
STE_STE20_FRAY_OXSR1_ST	Q13621	SLC12A1	O95747	OXSR1	T118	R116H	116	Missense	proximal	-2	no	46.996	47.399	EPSD;PhosphoSitePlus	ICGC;COSMIC;GDSC	17.710	Up-regulation
STE_STE20_FRAY_OXSR1_ST	Q13621	SLC12A1	O95747	OXSR1	T118	G123E	123	Missense	distal	5	no	46.996	46.866	EPSD;PhosphoSitePlus	ICGC	17.710	Down-regulation
STE_STE20_FRAY_OXSR1_ST	Q13621	SLC12A1	O95747	OXSR1	S120	E113D	113	Missense	distal	-7	no	46.596	46.593	EPSD;PhosphoSitePlus	ICGC	17.710	Down-regulation
STE_STE20_FRAY_OXSR1_ST	Q13621	SLC12A1	O95747	OXSR1	S120	S120I	120	Missense	central	0	yes	46.596	0.000	EPSD;PhosphoSitePlus	ICGC	17.710	Loss
STE_STE20_FRAY_OXSR1_ST	Q13621	SLC12A1	O95747	OXSR1	S120	P124T	124	Missense	distal	4	no	46.596	46.318	EPSD;PhosphoSitePlus	ICGC;COSMIC	17.710	Down-regulation
STE_STE20_FRAY_OXSR1_ST	Q13621	SLC12A1	O95747	OXSR1	S120	R116H	116	Missense	distal	-4	no	46.596	48.523	EPSD;PhosphoSitePlus	ICGC;COSMIC;GDSC	17.710	Up-regulation
STE_STE20_FRAY_OXSR1_ST	Q13621	SLC12A1	O95747	OXSR1	S120	G123E	123	Missense	distal	3	no	46.596	45.905	EPSD;PhosphoSitePlus	ICGC	17.710	Down-regulation
STE_STE20_FRAY_OXSR1_ST	Q13621	SLC12A1	O95747	OXSR1	S122	S120I	120	Missense	proximal	-2	no	19.343	18.385	EPSD	ICGC	17.710	Down-regulation
STE_STE20_FRAY_OXSR1_ST	Q13621	SLC12A1	O95747	OXSR1	S122	P124T	124	Missense	proximal	2	no	19.343	23.332	EPSD	ICGC;COSMIC	17.710	Up-regulation
STE_STE20_FRAY_OXSR1_ST	Q13621	SLC12A1	O95747	OXSR1	S122	R116H	116	Missense	distal	-6	no	19.343	19.702	EPSD	ICGC;COSMIC;GDSC	17.710	Up-regulation
STE_STE20_FRAY_OXSR1_ST	Q13621	SLC12A1	O95747	OXSR1	S122	G123E	123	Missense	proximal	1	no	19.343	18.810	EPSD	ICGC	17.710	Down-regulation
STE_STE20_FRAY_OXSR1_ST	Q13621	SLC12A1	O95747	OXSR1	T882	K875E	875	Missense	distal	-7	no	26.055	26.057	EPSD	ICGC;COSMIC	17.710	Up-regulation
STE_STE20_FRAY_OXSR1_ST	P55011	SLC12A2	O95747	OXSR1	T203	H204N	204	Missense	proximal	1	no	54.158	50.417	EPSD;PhosphoSitePlus	ICGC;COSMIC	17.710	Down-regulation
STE_STE20_FRAY_OXSR1_ST	P55011	SLC12A2	O95747	OXSR1	T207	H204N	204	Missense	distal	-3	no	48.398	44.279	PhosphoSitePlus;EPSD	ICGC;COSMIC	17.710	Down-regulation
STE_STE20_FRAY_OXSR1_ST	P55017	SLC12A3	O95747	OXSR1	T55	I61T	61	Missense	distal	6	no	45.147	44.632	EPSD;PhosphoSitePlus	ICGC	17.710	Down-regulation
STE_STE20_FRAY_OXSR1_ST	P55017	SLC12A3	O95747	OXSR1	T60	I61T	61	Missense	proximal	1	no	53.253	54.458	PhosphoSitePlus;EPSD	ICGC	17.710	Up-regulation
STE_STE20_FRAY_OXSR1_ST	P55017	SLC12A3	O95747	OXSR1	T66	I61T	61	Missense	distal	-5	no	20.194	28.167	EPSD	ICGC	17.710	Up-regulation
STE_STE20_FRAY_OXSR1_ST	P55017	SLC12A3	O95747	OXSR1	T85	V82F	82	Missense	distal	-3	no	14.801	23.208	EPSD	ICGC	17.710	Gain
TK_Src_SrcA_SRC_Y	Q14790	CASP8	P12931	SRC	Y8	I10T	10	Missense	proximal	2	no	19.695	20.772	EPSD	ICGC;COSMIC	20.673	Gain
TK_Src_SrcA_SRC_Y	Q14790	CASP8	P12931	SRC	Y8	L7V	7	Missense	proximal	-1	no	19.695	20.805	EPSD	ICGC;COSMIC	20.673	Gain
TK_Src_SrcA_SRC_Y	P60484	PTEN	P12931	SRC	Y46	V45E	45	Missense	proximal	-1	no	22.622	22.098	EPSD;PhosphoSitePlus	ICGC;COSMIC	20.673	Down-regulation
TK_Src_SrcA_SRC_Y	P60484	PTEN	P12931	SRC	Y46	G44C	44	Missense	proximal	-2	no	22.622	20.769	EPSD;PhosphoSitePlus	ICGC	20.673	Down-regulation
TK_Src_SrcA_SRC_Y	P60484	PTEN	P12931	SRC	Y46	Y46D	46	Missense	central	0	yes	22.622	0.000	EPSD;PhosphoSitePlus	ICGC;COSMIC	20.673	Loss
TK_Src_SrcA_SRC_Y	P60484	PTEN	P12931	SRC	Y46	N49K	49	Missense	distal	3	no	22.622	20.304	EPSD;PhosphoSitePlus	ICGC	20.673	Loss
TK_Src_SrcA_SRC_Y	P60484	PTEN	P12931	SRC	Y46	L42P	42	Missense	distal	-4	no	22.622	23.257	EPSD;PhosphoSitePlus	ICGC;COSMIC	20.673	Up-regulation
TK_Src_SrcA_SRC_Y	P60484	PTEN	P12931	SRC	Y176	Y177C	177	Missense	proximal	1	no	21.281	19.004	EPSD	ICGC;COSMIC	20.673	Loss
TK_Src_SrcA_SRC_Y	P60484	PTEN	P12931	SRC	Y176	Y177S	177	Missense	proximal	1	no	21.281	21.187	EPSD	ICGC;COSMIC	20.673	Down-regulation
TK_Src_SrcA_SRC_Y	P60484	PTEN	P12931	SRC	Y176	Y178S	178	Missense	proximal	2	no	21.281	21.721	EPSD	ICGC;COSMIC	20.673	Up-regulation
TK_Src_SrcA_SRC_Y	P60484	PTEN	P12931	SRC	Y176	V175L	175	Missense	proximal	-1	no	21.281	20.171	EPSD	ICGC;COSMIC	20.673	Loss
TK_Src_SrcA_SRC_Y	P60484	PTEN	P12931	SRC	Y177	Y177C	177	Missense	central	0	yes	21.132	0.000	EPSD	ICGC;COSMIC	20.673	Loss
TK_Src_SrcA_SRC_Y	P60484	PTEN	P12931	SRC	Y177	Y177S	177	Missense	central	0	yes	21.132	0.000	EPSD	ICGC;COSMIC	20.673	Loss
TK_Src_SrcA_SRC_Y	P60484	PTEN	P12931	SRC	Y177	Y178S	178	Missense	proximal	1	no	21.132	21.038	EPSD	ICGC;COSMIC	20.673	Down-regulation
TK_Src_SrcA_SRC_Y	P60484	PTEN	P12931	SRC	Y177	V175L	175	Missense	proximal	-2	no	21.132	21.051	EPSD	ICGC;COSMIC	20.673	Down-regulation
TK_Src_SrcA_SRC_Y	P60484	PTEN	P12931	SRC	Y240	P244R	244	Missense	distal	4	no	21.485	21.480	EPSD;PhosphoSitePlus	ICGC;COSMIC	20.673	Down-regulation
TK_Src_SrcA_SRC_Y	P60484	PTEN	P12931	SRC	Y315	D312Y	312	Missense	distal	-3	no	24.283	22.894	EPSD;PhosphoSitePlus	ICGC	20.673	Down-regulation
TK_Src_SrcA_SRC_Y	Q13813	SPTAN1	P12931	SRC	Y976	A974T	974	Missense	proximal	-2	no	20.548	20.676	EPSD	ICGC;COSMIC	20.673	Gain
TK_Src_SrcA_SRC_Y	Q13813	SPTAN1	P12931	SRC	Y976	A974S	974	Missense	proximal	-2	no	20.548	20.914	EPSD	ICGC	20.673	Gain
TK_Src_SrcA_SRC_Y	Q13813	SPTAN1	P12931	SRC	Y1176	M1178I	1178	Missense	proximal	2	no	22.468	21.539	EPSD;PhosphoSitePlus	ICGC	20.673	Down-regulation
TK_Src_SrcA_SRC_Y	Q13813	SPTAN1	P12931	SRC	Y1898	D1897Y	1897	Missense	proximal	-1	no	20.342	21.504	EPSD	ICGC	20.673	Gain
TK_Src_SrcA_SRC_Y	Q13813	SPTAN1	P12931	SRC	Y2423	V2424E	2424	Missense	proximal	1	no	19.480	21.362	EPSD	ICGC;COSMIC	20.673	Gain
TK_Src_SrcA_SRC_Y	Q13813	SPTAN1	P12931	SRC	Y2430	V2424E	2424	Missense	distal	-6	no	21.817	22.153	EPSD	ICGC;COSMIC	20.673	Up-regulation
TK_Src_SrcA_SRC_Y	P16035	TIMP2	P12931	SRC	Y62	D56N	56	Missense	distal	-6	no	23.336	23.146	EPSD;PhosphoSitePlus	ICGC	20.673	Down-regulation
TK_Src_SrcA_SRC_Y	P16035	TIMP2	P12931	SRC	Y62	P65T	65	Missense	distal	3	no	23.336	22.686	EPSD;PhosphoSitePlus	ICGC	20.673	Down-regulation
TK_Src_SrcA_SRC_Y	P35916	FLT4	P12931	SRC	Y833	Q837K	837	Missense	distal	4	no	21.340	21.334	EPSD;PhosphoSitePlus	ICGC;COSMIC	20.673	Down-regulation
TK_Src_SrcA_SRC_Y	P35916	FLT4	P12931	SRC	Y833	W838C	838	Missense	distal	5	no	21.340	21.183	EPSD;PhosphoSitePlus	ICGC;COSMIC	20.673	Down-regulation
TK_Src_SrcA_SRC_Y	P35916	FLT4	P12931	SRC	Y853	H846Q	846	Missense	distal	-7	no	20.985	21.055	EPSD;PhosphoSitePlus	ICGC	20.673	Up-regulation
TK_Src_SrcA_SRC_Y	P35916	FLT4	P12931	SRC	Y853	R849T	849	Missense	distal	-4	no	20.985	20.595	EPSD;PhosphoSitePlus	ICGC	20.673	Loss
TK_Src_SrcA_SRC_Y	P35916	FLT4	P12931	SRC	Y1063	Y1063H	1063	Missense	central	0	yes	20.766	0.000	EPSD;PhosphoSitePlus	ICGC;COSMIC	20.673	Loss
TK_Src_SrcA_SRC_Y	P35916	FLT4	P12931	SRC	Y1063	R1070H	1070	Missense	distal	7	no	20.766	20.752	EPSD;PhosphoSitePlus	ICGC;COSMIC	20.673	Down-regulation
TK_Src_SrcA_SRC_Y	P35916	FLT4	P12931	SRC	Y1063	D1067N	1067	Missense	distal	4	no	20.766	20.782	EPSD;PhosphoSitePlus	ICGC;COSMIC	20.673	Up-regulation
TK_Src_SrcA_SRC_Y	P35916	FLT4	P12931	SRC	Y1068	Y1063H	1063	Missense	distal	-5	no	21.795	22.460	EPSD	ICGC;COSMIC	20.673	Up-regulation
TK_Src_SrcA_SRC_Y	P35916	FLT4	P12931	SRC	Y1068	R1070H	1070	Missense	proximal	2	no	21.795	21.643	EPSD	ICGC;COSMIC	20.673	Down-regulation
TK_Src_SrcA_SRC_Y	P35916	FLT4	P12931	SRC	Y1068	D1067N	1067	Missense	proximal	-1	no	21.795	20.845	EPSD	ICGC;COSMIC	20.673	Down-regulation
TK_Src_SrcA_SRC_Y	P35916	FLT4	P12931	SRC	Y1068	R1075Q	1075	Missense	distal	7	no	21.795	21.752	EPSD	ICGC;COSMIC	20.673	Down-regulation
TK_Src_SrcA_SRC_Y	P35916	FLT4	P12931	SRC	Y1337	E1336K	1336	Missense	proximal	-1	no	21.735	19.826	EPSD;PhosphoSitePlus	ICGC;COSMIC;GDSC	20.673	Loss
TK_Src_SrcA_SRC_Y	P35916	FLT4	P12931	SRC	Y1337	N1334K	1334	Missense	distal	-3	no	21.735	20.486	EPSD;PhosphoSitePlus	ICGC;COSMIC	20.673	Loss
TK_Src_SrcA_SRC_Y	P35916	FLT4	P12931	SRC	Y1337	S1344N	1344	Missense	distal	7	no	21.735	21.702	EPSD;PhosphoSitePlus	ICGC;COSMIC	20.673	Down-regulation
TK_Src_SrcA_SRC_Y	P35916	FLT4	P12931	SRC	Y1337	G1338V	1338	Missense	proximal	1	no	21.735	20.837	EPSD;PhosphoSitePlus	ICGC;COSMIC	20.673	Down-regulation
TK_Src_SrcA_SRC_Y	P01112	HRAS	P12931	SRC	Y32	E37D	37	Missense	distal	5	no	20.815	20.608	EPSD;PhosphoSitePlus	ICGC;COSMIC	20.673	Loss
TK_Src_SrcA_SRC_Y	P01112	HRAS	P12931	SRC	Y64	A66T	66	Missense	proximal	2	no	23.344	23.438	EPSD;PhosphoSitePlus	ICGC;COSMIC	20.673	Up-regulation
TK_Src_SrcA_SRC_Y	Q9Y2W1	THRAP3	P12931	SRC	Y293	G290D	290	Missense	distal	-3	no	20.674	21.323	EPSD	ICGC;COSMIC	20.673	Up-regulation
TK_Src_SrcA_SRC_Y	Q9Y2W1	THRAP3	P12931	SRC	Y293	G296W	296	Missense	distal	3	no	20.674	19.293	EPSD	ICGC	20.673	Loss
TK_Src_SrcA_SRC_Y	Q9Y2W1	THRAP3	P12931	SRC	Y293	P288L	288	Missense	distal	-5	no	20.674	20.518	EPSD	ICGC;COSMIC;CCLE	20.673	Loss
TK_Src_SrcA_SRC_Y	Q9Y2W1	THRAP3	P12931	SRC	Y328	G329V	329	Missense	proximal	1	no	21.372	20.474	EPSD	ICGC	20.673	Loss
TK_Src_SrcA_SRC_Y	Q9Y2W1	THRAP3	P12931	SRC	Y476	E482K	482	Missense	distal	6	no	22.466	22.463	EPSD	ICGC;COSMIC	20.673	Down-regulation
TK_Src_SrcA_SRC_Y	Q9Y2W1	THRAP3	P12931	SRC	Y476	P478T	478	Missense	proximal	2	no	22.466	22.814	EPSD	ICGC;COSMIC	20.673	Up-regulation
TK_Src_SrcA_SRC_Y	Q9Y2W1	THRAP3	P12931	SRC	Y790	A792S	792	Missense	proximal	2	no	21.316	21.668	EPSD	ICGC	20.673	Up-regulation
TK_Src_SrcA_SRC_Y	Q9Y2W1	THRAP3	P12931	SRC	Y795	A792S	792	Missense	distal	-3	no	20.766	21.671	EPSD	ICGC	20.673	Up-regulation
TK_Src_SrcA_SRC_Y	P06396	GSN	P12931	SRC	Y465	A463T	463	Missense	proximal	-2	no	24.763	24.892	PhosphoSitePlus;EPSD	ICGC	20.673	Up-regulation
TK_Src_SrcA_SRC_Y	Q9H5V8	CDCP1	P12931	SRC	Y806	E802Q	802	Missense	distal	-4	no	22.731	21.900	EPSD	ICGC;COSMIC	20.673	Down-regulation
TK_Src_SrcA_SRC_Y	Q9H5V8	CDCP1	P12931	SRC	Y806	T807N	807	Missense	proximal	1	no	22.731	22.485	EPSD	ICGC	20.673	Down-regulation
TK_Src_SrcA_SRC_Y	P41235	HNF4A	P12931	SRC	Y23	A17P	17	Missense	distal	-6	no	22.972	23.012	EPSD;PhosphoSitePlus	ICGC	20.673	Up-regulation
TK_Src_SrcA_SRC_Y	P41235	HNF4A	P12931	SRC	Y286	L289I	289	Missense	distal	3	no	23.521	23.434	EPSD;PhosphoSitePlus	ICGC;COSMIC	20.673	Down-regulation
TK_Src_SrcA_SRC_Y	P41235	HNF4A	P12931	SRC	Y286	A291V	291	Missense	distal	5	no	23.521	23.663	EPSD;PhosphoSitePlus	ICGC	20.673	Up-regulation
TK_Src_SrcA_SRC_Y	P41235	HNF4A	P12931	SRC	Y286	E285D	285	Missense	proximal	-1	no	23.521	22.612	EPSD;PhosphoSitePlus	ICGC	20.673	Down-regulation
TK_Src_SrcA_SRC_Y	Q12879	GRIN2A	P12931	SRC	Y1118	D1121N	1121	Missense	distal	3	no	21.911	22.987	EPSD	ICGC;COSMIC	20.673	Up-regulation
TK_Src_SrcA_SRC_Y	Q12879	GRIN2A	P12931	SRC	Y1184	D1182N	1182	Missense	proximal	-2	no	22.095	21.815	EPSD;PhosphoSitePlus	ICGC;COSMIC	20.673	Down-regulation
TK_Src_SrcA_SRC_Y	Q12879	GRIN2A	P12931	SRC	Y1184	K1189M	1189	Missense	distal	5	no	22.095	22.405	EPSD;PhosphoSitePlus	ICGC;COSMIC	20.673	Up-regulation
TK_Src_SrcA_SRC_Y	Q12879	GRIN2A	P12931	SRC	Y1187	D1182N	1182	Missense	distal	-5	no	20.698	20.486	EPSD	ICGC;COSMIC	20.673	Loss
TK_Src_SrcA_SRC_Y	Q12879	GRIN2A	P12931	SRC	Y1187	K1189M	1189	Missense	proximal	2	no	20.698	21.634	EPSD	ICGC;COSMIC	20.673	Up-regulation
TK_Src_SrcA_SRC_Y	Q12879	GRIN2A	P12931	SRC	Y1267	G1263R	1263	Missense	distal	-4	no	23.865	23.847	EPSD;PhosphoSitePlus	ICGC;COSMIC	20.673	Down-regulation
TK_Src_SrcA_SRC_Y	Q12879	GRIN2A	P12931	SRC	Y1267	W1271L	1271	Missense	distal	4	no	23.865	23.927	EPSD;PhosphoSitePlus	ICGC;COSMIC	20.673	Up-regulation
TK_Src_SrcA_SRC_Y	Q12879	GRIN2A	P12931	SRC	Y1292	D1293N	1293	Missense	proximal	1	no	21.705	20.313	EPSD	ICGC;COSMIC	20.673	Loss
TK_Src_SrcA_SRC_Y	Q12879	GRIN2A	P12931	SRC	Y1292	S1287R	1287	Missense	distal	-5	no	21.705	21.621	EPSD	ICGC	20.673	Down-regulation
TK_Src_SrcA_SRC_Y	Q12879	GRIN2A	P12931	SRC	Y1292	P1299H	1299	Missense	distal	7	no	21.705	21.709	EPSD	ICGC	20.673	Up-regulation
TK_Src_SrcA_SRC_Y	Q12879	GRIN2A	P12931	SRC	Y1292	N1294D	1294	Missense	proximal	2	no	21.705	21.492	EPSD	ICGC	20.673	Down-regulation
TK_Src_SrcA_SRC_Y	Q12879	GRIN2A	P12931	SRC	Y1292	P1299L	1299	Missense	distal	7	no	21.705	21.698	EPSD	ICGC	20.673	Down-regulation
TK_Src_SrcA_SRC_Y	Q12879	GRIN2A	P12931	SRC	Y1292	D1297V	1297	Missense	distal	5	no	21.705	21.960	EPSD	ICGC;COSMIC	20.673	Up-regulation
TK_Src_SrcA_SRC_Y	Q12879	GRIN2A	P12931	SRC	Y1325	L1320R	1320	Missense	distal	-5	no	24.289	24.463	PhosphoSitePlus;EPSD	ICGC;COSMIC	20.673	Up-regulation
TK_Src_SrcA_SRC_Y	Q12879	GRIN2A	P12931	SRC	Y1325	P1332S	1332	Missense	distal	7	no	24.289	24.269	PhosphoSitePlus;EPSD	ICGC	20.673	Down-regulation
TK_Src_SrcA_SRC_Y	P40763	STAT3	P12931	SRC	Y79	H81Q	81	Missense	proximal	2	no	21.754	22.256	EPSD	ICGC	20.673	Up-regulation
TK_Src_SrcA_SRC_Y	P40763	STAT3	P12931	SRC	Y446	G449D	449	Missense	distal	3	no	21.778	21.405	EPSD	ICGC;COSMIC	20.673	Down-regulation
TK_Src_SrcA_SRC_Y	P40763	STAT3	P12931	SRC	Y446	D453E	453	Missense	distal	7	no	21.778	21.816	EPSD	ICGC	20.673	Up-regulation
TK_Src_SrcA_SRC_Y	P40763	STAT3	P12931	SRC	Y446	E442K	442	Missense	distal	-4	no	21.778	20.608	EPSD	ICGC	20.673	Loss
TK_Src_SrcA_SRC_Y	O15379	HDAC3	P12931	SRC	Y207	V209I	209	Missense	proximal	2	no	24.457	23.262	EPSD	ICGC;COSMIC	20.673	Down-regulation
TK_Src_SrcA_SRC_Y	O15379	HDAC3	P12931	SRC	Y207	A211E	211	Missense	distal	4	no	24.457	24.446	EPSD	ICGC	20.673	Down-regulation
TK_Src_SrcA_SRC_Y	O15379	HDAC3	P12931	SRC	Y207	G210V	210	Missense	distal	3	no	24.457	24.833	EPSD	ICGC;COSMIC	20.673	Up-regulation
TK_Src_SrcA_SRC_Y	O15379	HDAC3	P12931	SRC	Y207	P201T	201	Missense	distal	-6	no	24.457	24.454	EPSD	ICGC;COSMIC	20.673	Down-regulation
TK_Src_SrcA_SRC_Y	O15379	HDAC3	P12931	SRC	Y207	P201H	201	Missense	distal	-6	no	24.457	24.333	EPSD	ICGC;COSMIC	20.673	Down-regulation
TK_Src_SrcA_SRC_Y	O15379	HDAC3	P12931	SRC	Y404	A409E	409	Missense	distal	5	no	22.247	22.340	EPSD	ICGC	20.673	Up-regulation
TK_Src_SrcA_SRC_Y	P52732	KIF11	P12931	SRC	Y82	R83Q	83	Missense	proximal	1	no	21.086	22.078	EPSD	ICGC;COSMIC	20.673	Up-regulation
TK_Src_SrcA_SRC_Y	P52732	KIF11	P12931	SRC	Y82	S84I	84	Missense	proximal	2	no	21.086	19.750	EPSD	ICGC	20.673	Loss
TK_Src_SrcA_SRC_Y	P52732	KIF11	P12931	SRC	Y399	I400V	400	Missense	proximal	1	no	22.269	22.929	EPSD	ICGC;COSMIC	20.673	Up-regulation
TK_Src_SrcA_SRC_Y	P52732	KIF11	P12931	SRC	Y399	A392T	392	Missense	distal	-7	no	22.269	22.689	EPSD	ICGC;COSMIC	20.673	Up-regulation
TK_Src_SrcA_SRC_Y	P31645	SLC6A4	P12931	SRC	Y47	Q42K	42	Missense	distal	-5	no	21.046	20.897	EPSD;PhosphoSitePlus	ICGC;COSMIC	20.673	Down-regulation
TK_Src_SrcA_SRC_Y	P31645	SLC6A4	P12931	SRC	Y47	S52R	52	Missense	distal	5	no	21.046	21.071	EPSD;PhosphoSitePlus	ICGC;COSMIC	20.673	Up-regulation
TK_Src_SrcA_SRC_Y	Q7Z3C6	ATG9A	P12931	SRC	Y8	T6P	6	Missense	proximal	-2	no	21.985	23.009	PhosphoSitePlus;EPSD	ICGC;COSMIC	20.673	Up-regulation
TK_Src_SrcA_SRC_Y	Q7Z3C6	ATG9A	P12931	SRC	Y209	L203V	203	Missense	distal	-6	no	20.973	20.792	EPSD	ICGC	20.673	Down-regulation
TK_Src_SrcA_SRC_Y	Q7Z3C6	ATG9A	P12931	SRC	Y209	R214C	214	Missense	distal	5	no	20.973	21.406	EPSD	ICGC;COSMIC	20.673	Up-regulation
TK_Src_SrcA_SRC_Y	Q8NER1	TRPV1	P12931	SRC	Y199	A193V	193	Missense	distal	-6	no	22.155	21.994	EPSD	ICGC;COSMIC	20.673	Down-regulation
TK_Src_SrcA_SRC_Y	Q8NER1	TRPV1	P12931	SRC	Y199	D197E	197	Missense	proximal	-2	no	22.155	22.442	EPSD	ICGC	20.673	Up-regulation
TK_Src_SrcA_SRC_Y	Q8NER1	TRPV1	P12931	SRC	Y565	M562T	562	Missense	distal	-3	no	19.967	21.196	EPSD	ICGC;COSMIC	20.673	Gain
TK_Src_SrcA_SRC_Y	P16885	PLCG2	P12931	SRC	Y680	R674Q	674	Missense	distal	-6	no	21.180	21.282	EPSD	ICGC;COSMIC	20.673	Up-regulation
TK_Src_SrcA_SRC_Y	P16885	PLCG2	P12931	SRC	Y680	A686D	686	Missense	distal	6	no	21.180	21.155	EPSD	ICGC;COSMIC	20.673	Down-regulation
TK_Src_SrcA_SRC_Y	P16885	PLCG2	P12931	SRC	Y720	R727L	727	Missense	distal	7	no	21.309	21.284	EPSD	ICGC	20.673	Down-regulation
TK_Src_SrcA_SRC_Y	P16885	PLCG2	P12931	SRC	Y753	D748Y	748	Missense	distal	-5	no	21.079	20.456	PhosphoSitePlus;EPSD	ICGC;COSMIC	20.673	Loss
TK_Src_SrcA_SRC_Y	P16885	PLCG2	P12931	SRC	Y1048	P1052L	1052	Missense	distal	4	no	22.202	22.230	EPSD	ICGC	20.673	Up-regulation
TK_Src_SrcA_SRC_Y	P19022	CDH2	P12931	SRC	Y496	Y496H	496	Missense	central	0	yes	21.765	0.000	EPSD	ICGC;COSMIC	20.673	Loss
TK_Src_SrcA_SRC_Y	P19022	CDH2	P12931	SRC	Y785	E780K	780	Missense	distal	-5	no	21.935	21.358	EPSD	ICGC;COSMIC	20.673	Down-regulation
TK_Src_SrcA_SRC_Y	Q96J92	WNK4	P12931	SRC	Y373	P374Q	374	Missense	proximal	1	no	19.679	21.938	EPSD	ICGC;COSMIC	20.673	Gain
TK_Src_SrcA_SRC_Y	Q96J92	WNK4	P12931	SRC	Y375	P374Q	374	Missense	proximal	-1	no	20.778	20.944	EPSD	ICGC;COSMIC	20.673	Up-regulation
TK_Src_SrcA_SRC_Y	Q03135	CAV1	P12931	SRC	Y14	V7L	7	Missense	distal	-7	no	22.478	22.515	PhosphoSitePlus	ICGC	20.673	Up-regulation
TK_Src_SrcA_SRC_Y	Q03135	CAV1	P12931	SRC	Y14	E10D	10	Missense	distal	-4	no	22.478	22.704	PhosphoSitePlus	ICGC	20.673	Up-regulation
TK_Src_SrcA_SRC_Y	Q03135	CAV1	P12931	SRC	Y14	V16I	16	Missense	proximal	2	no	22.478	21.284	PhosphoSitePlus	ICGC;COSMIC	20.673	Down-regulation
TK_Src_SrcA_SRC_Y	Q03135	CAV1	P12931	SRC	Y14	R19L	19	Missense	distal	5	no	22.478	22.646	PhosphoSitePlus	ICGC;COSMIC	20.673	Up-regulation
TK_Src_SrcA_SRC_Y	Q03135	CAV1	P12931	SRC	Y25	R19L	19	Missense	distal	-6	no	21.787	21.859	EPSD	ICGC;COSMIC	20.673	Up-regulation
TK_Src_SrcA_SRC_Y	Q03135	CAV1	P12931	SRC	Y42	A44T	44	Missense	proximal	2	no	23.755	23.848	EPSD	ICGC;COSMIC	20.673	Up-regulation
TK_Src_SrcA_SRC_Y	Q03135	CAV1	P12931	SRC	Y42	E35D	35	Missense	distal	-7	no	23.755	23.726	EPSD	ICGC	20.673	Down-regulation
TK_Src_SrcA_SRC_Y	Q9Y2X7	GIT1	P12931	SRC	Y224	T227N	227	Missense	distal	3	no	21.866	22.718	EPSD	ICGC;COSMIC	20.673	Up-regulation
TK_Src_SrcA_SRC_Y	Q9Y2X7	GIT1	P12931	SRC	Y284	E277K	277	Missense	distal	-7	no	23.461	23.298	PhosphoSitePlus;EPSD	ICGC;COSMIC	20.673	Down-regulation
TK_Src_SrcA_SRC_Y	Q9Y2X7	GIT1	P12931	SRC	Y284	A280V	280	Missense	distal	-4	no	23.461	23.328	PhosphoSitePlus;EPSD	ICGC;COSMIC	20.673	Down-regulation
TK_Src_SrcA_SRC_Y	Q9Y2X7	GIT1	P12931	SRC	Y284	D285G	285	Missense	proximal	1	no	23.461	23.083	PhosphoSitePlus;EPSD	ICGC	20.673	Down-regulation
TK_Src_SrcA_SRC_Y	Q9Y2X7	GIT1	P12931	SRC	Y321	P319L	319	Missense	proximal	-2	no	21.299	19.769	EPSD;PhosphoSitePlus	ICGC;COSMIC;CCLE	20.673	Loss
TK_Src_SrcA_SRC_Y	Q9Y2X7	GIT1	P12931	SRC	Y383	S385R	385	Missense	proximal	2	no	23.055	22.224	EPSD	ICGC	20.673	Down-regulation
TK_Src_SrcA_SRC_Y	Q9Y2X7	GIT1	P12931	SRC	Y383	A387D	387	Missense	distal	4	no	23.055	23.073	EPSD	ICGC	20.673	Up-regulation
TK_Src_SrcA_SRC_Y	Q9Y2X7	GIT1	P12931	SRC	Y383	D382N	382	Missense	proximal	-1	no	23.055	22.106	EPSD	ICGC	20.673	Down-regulation
TK_Src_SrcA_SRC_Y	Q9Y2X7	GIT1	P12931	SRC	Y545	D542N	542	Missense	distal	-3	no	22.449	21.941	EPSD	ICGC;COSMIC	20.673	Down-regulation
TK_Src_SrcA_SRC_Y	Q9Y2X7	GIT1	P12931	SRC	Y545	A543T	543	Missense	proximal	-2	no	22.449	22.578	EPSD	ICGC;COSMIC	20.673	Up-regulation
TK_Src_SrcA_SRC_Y	Q9Y2X7	GIT1	P12931	SRC	Y545	I544L	544	Missense	proximal	-1	no	22.449	21.714	EPSD	ICGC;COSMIC	20.673	Down-regulation
TK_Src_SrcA_SRC_Y	Q9Y2X7	GIT1	P12931	SRC	Y598	T601M	601	Missense	distal	3	no	22.344	22.503	EPSD	ICGC;COSMIC	20.673	Up-regulation
TK_Src_SrcA_SRC_Y	Q9Y2X7	GIT1	P12931	SRC	Y598	E599D	599	Missense	proximal	1	no	22.344	21.738	EPSD	ICGC	20.673	Down-regulation
TK_Src_SrcA_SRC_Y	Q13480	GAB1	P12931	SRC	Y259	V254G	254	Missense	distal	-5	no	20.690	20.719	EPSD;PhosphoSitePlus	ICGC;COSMIC	20.673	Up-regulation
TK_Src_SrcA_SRC_Y	Q13480	GAB1	P12931	SRC	Y259	D255Y	255	Missense	distal	-4	no	20.690	19.696	EPSD;PhosphoSitePlus	ICGC	20.673	Loss
TK_Src_SrcA_SRC_Y	Q13480	GAB1	P12931	SRC	Y285	G292W	292	Missense	distal	7	no	22.654	22.757	EPSD	ICGC;COSMIC	20.673	Up-regulation
TK_Src_SrcA_SRC_Y	Q13480	GAB1	P12931	SRC	Y406	A400V	400	Missense	distal	-6	no	21.248	21.088	EPSD	ICGC	20.673	Down-regulation
TK_Src_SrcA_SRC_Y	Q13480	GAB1	P12931	SRC	Y447	V448I	448	Missense	proximal	1	no	20.885	20.225	EPSD	ICGC;COSMIC	20.673	Loss
TK_Src_SrcA_SRC_Y	Q13480	GAB1	P12931	SRC	Y447	D444Y	444	Missense	distal	-3	no	20.885	19.496	EPSD	ICGC	20.673	Loss
TK_Src_SrcA_SRC_Y	Q13480	GAB1	P12931	SRC	Y447	M450I	450	Missense	distal	3	no	20.885	21.191	EPSD	ICGC	20.673	Up-regulation
TK_Src_SrcA_SRC_Y	O43823	AKAP8	P12931	SRC	Y146	N144D	144	Missense	proximal	-2	no	21.034	21.314	EPSD;PhosphoSitePlus	ICGC;COSMIC	20.673	Up-regulation
TK_Src_SrcA_SRC_Y	O43823	AKAP8	P12931	SRC	Y146	H143N	143	Missense	distal	-3	no	21.034	22.102	EPSD;PhosphoSitePlus	ICGC	20.673	Up-regulation
TK_Src_SrcA_SRC_Y	O43823	AKAP8	P12931	SRC	Y146	P148H	148	Missense	proximal	2	no	21.034	20.657	EPSD;PhosphoSitePlus	ICGC;COSMIC	20.673	Loss
TK_Src_SrcA_SRC_Y	O43823	AKAP8	P12931	SRC	Y146	R147H	147	Missense	proximal	1	no	21.034	20.960	EPSD;PhosphoSitePlus	ICGC;COSMIC;CCLE	20.673	Down-regulation
TK_Src_SrcA_SRC_Y	O43823	AKAP8	P12931	SRC	Y170	P176L	176	Missense	distal	6	no	21.005	21.021	EPSD;PhosphoSitePlus	ICGC;COSMIC	20.673	Up-regulation
TK_Src_SrcA_SRC_Y	Q92945	KHSRP	P12931	SRC	Y149	T146K	146	Missense	distal	-3	no	21.215	20.637	EPSD	ICGC	20.673	Loss
TK_Src_SrcA_SRC_Y	Q92945	KHSRP	P12931	SRC	Y149	T143N	143	Missense	distal	-6	no	21.215	21.241	EPSD	ICGC	20.673	Up-regulation
TK_Src_SrcA_SRC_Y	Q92945	KHSRP	P12931	SRC	Y149	P152Q	152	Missense	distal	3	no	21.215	19.841	EPSD	ICGC;COSMIC	20.673	Loss
TK_Src_SrcA_SRC_Y	Q92945	KHSRP	P12931	SRC	Y149	E148D	148	Missense	proximal	-1	no	21.215	20.305	EPSD	ICGC	20.673	Loss
TK_Src_SrcA_SRC_Y	Q92945	KHSRP	P12931	SRC	Y149	R150S	150	Missense	proximal	1	no	21.215	22.094	EPSD	ICGC;COSMIC	20.673	Up-regulation
TK_Src_SrcA_SRC_Y	Q92945	KHSRP	P12931	SRC	Y317	G318R	318	Missense	proximal	1	no	21.728	20.735	EPSD;PhosphoSitePlus	ICGC;COSMIC	20.673	Down-regulation
TK_Src_SrcA_SRC_Y	Q92945	KHSRP	P12931	SRC	Y317	S319Y	319	Missense	proximal	2	no	21.728	21.287	EPSD;PhosphoSitePlus	ICGC;COSMIC	20.673	Down-regulation
TK_Src_SrcA_SRC_Y	Q92945	KHSRP	P12931	SRC	Y317	G310D	310	Missense	distal	-7	no	21.728	22.150	EPSD;PhosphoSitePlus	ICGC;COSMIC	20.673	Up-regulation
TK_Src_SrcA_SRC_Y	Q92945	KHSRP	P12931	SRC	Y583	P590L	590	Missense	distal	7	no	22.049	22.043	PhosphoSitePlus;EPSD	ICGC	20.673	Down-regulation
TK_Src_SrcA_SRC_Y	Q92945	KHSRP	P12931	SRC	Y674	P668A	668	Missense	distal	-6	no	21.239	21.199	EPSD	ICGC;COSMIC	20.673	Down-regulation
TK_Src_SrcA_SRC_Y	P61978	HNRNPK	P12931	SRC	Y225	P227L	227	Missense	proximal	2	no	24.096	23.640	EPSD;PhosphoSitePlus	ICGC	20.673	Down-regulation
TK_Src_SrcA_SRC_Y	P61978	HNRNPK	P12931	SRC	Y225	D231Y	231	Missense	distal	6	no	24.096	24.151	EPSD;PhosphoSitePlus	ICGC;COSMIC	20.673	Up-regulation
TK_Src_SrcA_SRC_Y	P61978	HNRNPK	P12931	SRC	Y230	P227L	227	Missense	distal	-3	no	20.802	19.651	EPSD;PhosphoSitePlus	ICGC	20.673	Loss
TK_Src_SrcA_SRC_Y	P61978	HNRNPK	P12931	SRC	Y230	D231Y	231	Missense	proximal	1	no	20.802	20.403	EPSD;PhosphoSitePlus	ICGC;COSMIC	20.673	Loss
TK_Src_SrcA_SRC_Y	P61978	HNRNPK	P12931	SRC	Y234	P227L	227	Missense	distal	-7	no	23.464	23.349	PhosphoSitePlus;EPSD	ICGC	20.673	Down-regulation
TK_Src_SrcA_SRC_Y	P61978	HNRNPK	P12931	SRC	Y234	D231Y	231	Missense	distal	-3	no	23.464	22.075	PhosphoSitePlus;EPSD	ICGC;COSMIC	20.673	Down-regulation
TK_Src_SrcA_SRC_Y	P61978	HNRNPK	P12931	SRC	Y236	D231Y	231	Missense	distal	-5	no	22.448	21.824	EPSD;PhosphoSitePlus	ICGC;COSMIC	20.673	Down-regulation
TK_Src_SrcA_SRC_Y	P61978	HNRNPK	P12931	SRC	Y333	G335D	335	Missense	proximal	2	no	20.981	21.648	EPSD	ICGC;COSMIC	20.673	Up-regulation
TK_Src_SrcA_SRC_Y	P61978	HNRNPK	P12931	SRC	Y369	A374E	374	Missense	distal	5	no	20.658	20.752	EPSD	ICGC	20.673	Gain
TK_Src_SrcA_SRC_Y	P23246	SFPQ	P12931	SRC	Y293	Q295K	295	Missense	proximal	2	no	21.695	20.834	EPSD	ICGC	20.673	Down-regulation
TK_Src_SrcA_SRC_Y	P23246	SFPQ	P12931	SRC	Y293	T294K	294	Missense	proximal	1	no	21.695	21.053	EPSD	ICGC	20.673	Down-regulation
TK_Src_SrcA_SRC_Y	P23246	SFPQ	P12931	SRC	Y293	R298W	298	Missense	distal	5	no	21.695	22.287	EPSD	ICGC	20.673	Up-regulation
TK_Src_SrcA_SRC_Y	P23246	SFPQ	P12931	SRC	Y488	Y488H	488	Missense	central	0	yes	21.123	0.000	EPSD	ICGC;COSMIC	20.673	Loss
TK_Src_SrcA_SRC_Y	P23246	SFPQ	P12931	SRC	Y488	E489K	489	Missense	proximal	1	no	21.123	18.729	EPSD	ICGC;COSMIC	20.673	Loss
TK_Src_SrcA_SRC_Y	P23246	SFPQ	P12931	SRC	Y488	S491P	491	Missense	distal	3	no	21.123	21.862	EPSD	ICGC;COSMIC	20.673	Up-regulation
TK_Src_SrcA_SRC_Y	P23246	SFPQ	P12931	SRC	Y488	H483N	483	Missense	distal	-5	no	21.123	20.869	EPSD	ICGC	20.673	Down-regulation
TK_Src_SrcA_SRC_Y	P23246	SFPQ	P12931	SRC	Y488	T485K	485	Missense	distal	-3	no	21.123	20.545	EPSD	ICGC	20.673	Loss
TK_Src_SrcA_SRC_Y	P23246	SFPQ	P12931	SRC	Y597	R593K	593	Missense	distal	-4	no	22.451	21.732	EPSD;PhosphoSitePlus	ICGC;COSMIC	20.673	Down-regulation
TK_Src_SrcA_SRC_Y	P23246	SFPQ	P12931	SRC	Y597	E594Q	594	Missense	distal	-3	no	22.451	21.571	EPSD;PhosphoSitePlus	ICGC;COSMIC	20.673	Down-regulation
TK_Src_SrcA_SRC_Y	P23246	SFPQ	P12931	SRC	Y597	S598R	598	Missense	proximal	1	no	22.451	21.572	EPSD;PhosphoSitePlus	ICGC	20.673	Down-regulation
TK_Src_SrcA_SRC_Y	P23246	SFPQ	P12931	SRC	Y698	N702K	702	Missense	distal	4	no	21.343	21.299	EPSD	ICGC	20.673	Down-regulation
TK_Src_SrcA_SRC_Y	P23246	SFPQ	P12931	SRC	Y698	G692C	692	Missense	distal	-6	no	21.343	20.948	EPSD	ICGC	20.673	Down-regulation
TK_Src_SrcA_SRC_Y	O14641	DVL2	P12931	SRC	Y295	G292R	292	Missense	distal	-3	no	21.058	20.165	EPSD;PhosphoSitePlus	ICGC	20.673	Loss
TK_Src_SrcA_SRC_Y	P15311	EZR	P12931	SRC	Y116	P118T	118	Missense	proximal	2	no	20.745	21.094	EPSD	ICGC	20.673	Up-regulation
TK_Src_SrcA_SRC_Y	P15311	EZR	P12931	SRC	Y116	I110T	110	Missense	distal	-6	no	20.745	20.716	EPSD	ICGC	20.673	Down-regulation
TK_Src_SrcA_SRC_Y	P15311	EZR	P12931	SRC	Y478	P471L	471	Missense	distal	-7	no	25.069	24.954	PhosphoSitePlus;EPSD	ICGC;COSMIC;GDSC	20.673	Down-regulation
TK_Src_SrcA_SRC_Y	P15311	EZR	P12931	SRC	Y478	P471Q	471	Missense	distal	-7	no	25.069	25.213	PhosphoSitePlus;EPSD	ICGC	20.673	Up-regulation
TK_Src_SrcA_SRC_Y	P15311	EZR	P12931	SRC	Y478	P472T	472	Missense	distal	-6	no	25.069	25.066	PhosphoSitePlus;EPSD	ICGC	20.673	Down-regulation
TK_Src_SrcA_SRC_Y	Q15139	PRKD1	P12931	SRC	Y502	V507I	507	Missense	distal	5	no	21.516	21.567	EPSD;PhosphoSitePlus	ICGC;COSMIC	20.673	Up-regulation
TK_Src_SrcA_SRC_Y	Q93052	LPP	P12931	SRC	Y244	G250A	250	Missense	distal	6	no	22.155	22.139	PhosphoSitePlus;EPSD	ICGC;COSMIC	20.673	Down-regulation
TK_Src_SrcA_SRC_Y	Q93052	LPP	P12931	SRC	Y287	A290S	290	Missense	distal	3	no	21.800	21.756	EPSD	ICGC;COSMIC	20.673	Down-regulation
TK_Src_SrcA_SRC_Y	Q93052	LPP	P12931	SRC	Y296	Y300H	300	Missense	distal	4	no	21.345	21.367	EPSD	ICGC;COSMIC	20.673	Up-regulation
TK_Src_SrcA_SRC_Y	Q93052	LPP	P12931	SRC	Y296	A290S	290	Missense	distal	-6	no	21.345	21.435	EPSD	ICGC;COSMIC	20.673	Up-regulation
TK_Src_SrcA_SRC_Y	Q93052	LPP	P12931	SRC	Y296	R295C	295	Missense	proximal	-1	no	21.345	22.767	EPSD	ICGC;COSMIC	20.673	Up-regulation
TK_Src_SrcA_SRC_Y	Q93052	LPP	P12931	SRC	Y297	Y300H	300	Missense	distal	3	no	22.001	21.903	EPSD	ICGC;COSMIC	20.673	Down-regulation
TK_Src_SrcA_SRC_Y	Q93052	LPP	P12931	SRC	Y297	A290S	290	Missense	distal	-7	no	22.001	22.325	EPSD	ICGC;COSMIC	20.673	Up-regulation
TK_Src_SrcA_SRC_Y	Q93052	LPP	P12931	SRC	Y297	R295C	295	Missense	proximal	-2	no	22.001	21.505	EPSD	ICGC;COSMIC	20.673	Down-regulation
TK_Src_SrcA_SRC_Y	Q93052	LPP	P12931	SRC	Y301	Y300H	300	Missense	proximal	-1	no	22.380	21.785	EPSD;PhosphoSitePlus	ICGC;COSMIC	20.673	Down-regulation
TK_Src_SrcA_SRC_Y	Q93052	LPP	P12931	SRC	Y301	R295C	295	Missense	distal	-6	no	22.380	21.983	EPSD;PhosphoSitePlus	ICGC;COSMIC	20.673	Down-regulation
TK_Src_SrcA_SRC_Y	Q93052	LPP	P12931	SRC	Y317	P315H	315	Missense	proximal	-2	no	23.340	22.675	EPSD	ICGC	20.673	Down-regulation
TK_Src_SrcA_SRC_Y	Q93052	LPP	P12931	SRC	Y317	G318D	318	Missense	proximal	1	no	23.340	23.718	EPSD	ICGC;COSMIC	20.673	Up-regulation
TK_Src_SrcA_SRC_Y	Q93052	LPP	P12931	SRC	Y332	G331R	331	Missense	proximal	-1	no	20.717	19.945	EPSD	ICGC;COSMIC	20.673	Loss
TK_Src_SrcA_SRC_Y	Q93052	LPP	P12931	SRC	Y346	P347S	347	Missense	proximal	1	no	19.078	21.224	EPSD	ICGC	20.673	Gain
TK_Src_SrcA_SRC_Y	P04439	HLA-A	P12931	SRC	Y147	Y142H	142	Missense	distal	-5	no	20.015	20.681	EPSD	ICGC	20.673	Gain
TK_Src_SrcA_SRC_Y	P53355	DAPK1	P12931	SRC	Y12	Q6H	6	Missense	distal	-6	no	21.097	20.962	EPSD	ICGC;COSMIC;GDSC;CCLE	20.673	Down-regulation
TK_Src_SrcA_SRC_Y	P53355	DAPK1	P12931	SRC	Y13	Q6H	6	Missense	distal	-7	no	22.105	22.034	EPSD	ICGC;COSMIC;GDSC;CCLE	20.673	Down-regulation
TK_Src_SrcA_SRC_Y	O15492	RGS16	P12931	SRC	Y168	R170C	170	Missense	proximal	2	no	21.869	21.269	EPSD;PhosphoSitePlus	ICGC;COSMIC;CCLE	20.673	Down-regulation
TK_Src_SrcA_SRC_Y	O15492	RGS16	P12931	SRC	Y168	E164K	164	Missense	distal	-4	no	21.869	20.699	EPSD;PhosphoSitePlus	ICGC	20.673	Down-regulation
TK_Src_SrcA_SRC_Y	O15492	RGS16	P12931	SRC	Y177	R170C	170	Missense	distal	-7	no	21.421	20.280	PhosphoSitePlus;EPSD	ICGC;COSMIC;CCLE	20.673	Loss
TK_Src_SrcA_SRC_Y	O15492	RGS16	P12931	SRC	Y177	R178Q	178	Missense	proximal	1	no	21.421	22.414	PhosphoSitePlus;EPSD	ICGC;COSMIC	20.673	Up-regulation
TK_Src_SrcA_SRC_Y	O15492	RGS16	P12931	SRC	Y177	D179E	179	Missense	proximal	2	no	21.421	21.709	PhosphoSitePlus;EPSD	ICGC	20.673	Up-regulation
TK_Src_SrcA_SRC_Y	Q9Y371	SH3GLB1	P12931	SRC	Y80	V79L	79	Missense	proximal	-1	no	23.958	22.848	PhosphoSitePlus	ICGC;COSMIC	20.673	Down-regulation
TK_Src_SrcA_SRC_Y	Q9Y371	SH3GLB1	P12931	SRC	Y155	D154Y	154	Missense	proximal	-1	no	19.578	20.740	EPSD	ICGC	20.673	Gain
TK_Src_SrcA_SRC_Y	Q9UPT8	ZC3H4	P12931	SRC	Y190	D195E	195	Missense	distal	5	no	21.179	21.387	EPSD	ICGC;COSMIC	20.673	Up-regulation
TK_Src_SrcA_SRC_Y	Q9UPT8	ZC3H4	P12931	SRC	Y193	D195E	195	Missense	proximal	2	no	21.031	21.318	EPSD	ICGC;COSMIC	20.673	Up-regulation
TK_Src_SrcA_SRC_Y	Q9UPT8	ZC3H4	P12931	SRC	Y196	D195E	195	Missense	proximal	-1	no	23.086	23.996	EPSD	ICGC;COSMIC	20.673	Up-regulation
TK_Src_SrcA_SRC_Y	Q9UPT8	ZC3H4	P12931	SRC	Y201	E208D	208	Missense	distal	7	no	22.368	22.330	EPSD	ICGC;COSMIC;GDSC;CCLE	20.673	Down-regulation
TK_Src_SrcA_SRC_Y	Q9UPT8	ZC3H4	P12931	SRC	Y201	D195E	195	Missense	distal	-6	no	22.368	22.290	EPSD	ICGC;COSMIC	20.673	Down-regulation
TK_Src_SrcA_SRC_Y	Q9UPT8	ZC3H4	P12931	SRC	Y204	E208D	208	Missense	distal	4	no	21.334	21.361	EPSD	ICGC;COSMIC;GDSC;CCLE	20.673	Up-regulation
TK_Src_SrcA_SRC_Y	Q9UPT8	ZC3H4	P12931	SRC	Y217	D219N	219	Missense	proximal	2	no	23.941	24.155	EPSD	ICGC;COSMIC	20.673	Up-regulation
TK_Src_SrcA_SRC_Y	Q9UPT8	ZC3H4	P12931	SRC	Y217	M212T	212	Missense	distal	-5	no	23.941	24.049	EPSD	ICGC;COSMIC	20.673	Up-regulation
TK_Src_SrcA_SRC_Y	Q9UPT8	ZC3H4	P12931	SRC	Y217	F220C	220	Missense	distal	3	no	23.941	22.224	EPSD	ICGC;COSMIC	20.673	Down-regulation
TK_Src_SrcA_SRC_Y	Q9UPT8	ZC3H4	P12931	SRC	Y217	L224V	224	Missense	distal	7	no	23.941	23.993	EPSD	ICGC;COSMIC	20.673	Up-regulation
TK_Src_SrcA_SRC_Y	Q9UPT8	ZC3H4	P12931	SRC	Y364	D367E	367	Missense	distal	3	no	22.518	22.613	EPSD	ICGC	20.673	Up-regulation
TK_Src_SrcA_SRC_Y	Q9UPT8	ZC3H4	P12931	SRC	Y364	D370E	370	Missense	distal	6	no	22.518	22.569	EPSD	ICGC	20.673	Up-regulation
TK_Src_SrcA_SRC_Y	Q9UPT8	ZC3H4	P12931	SRC	Y364	G371C	371	Missense	distal	7	no	22.518	22.598	EPSD	ICGC;COSMIC	20.673	Up-regulation
TK_Src_SrcA_SRC_Y	Q9UPT8	ZC3H4	P12931	SRC	Y1218	P1211H	1211	Missense	distal	-7	no	22.748	22.822	EPSD;PhosphoSitePlus	ICGC;COSMIC	20.673	Up-regulation
TK_Src_SrcA_SRC_Y	Q9NWQ8	PAG1	P12931	SRC	Y387	Y387C	387	Missense	central	0	yes	24.001	0.000	EPSD	ICGC;COSMIC	20.673	Loss
TK_Src_SrcA_SRC_Y	Q9NWQ8	PAG1	P12931	SRC	Y387	E381K	381	Missense	distal	-6	no	24.001	23.989	EPSD	ICGC;COSMIC	20.673	Down-regulation
TK_Src_SrcA_SRC_Y	Q9NWQ8	PAG1	P12931	SRC	Y387	P383T	383	Missense	distal	-4	no	24.001	23.934	EPSD	ICGC	20.673	Down-regulation
TK_Src_SrcA_SRC_Y	Q16832	DDR2	P12931	SRC	Y471	L477I	477	Missense	distal	6	no	21.934	21.923	EPSD;PhosphoSitePlus	ICGC;COSMIC	20.673	Down-regulation
TK_Src_SrcA_SRC_Y	Q16832	DDR2	P12931	SRC	Y471	R478C	478	Missense	distal	7	no	21.934	22.006	EPSD;PhosphoSitePlus	ICGC;COSMIC	20.673	Up-regulation
TK_Src_SrcA_SRC_Y	Q16832	DDR2	P12931	SRC	Y471	S467P	467	Missense	distal	-4	no	21.934	21.881	EPSD;PhosphoSitePlus	ICGC	20.673	Down-regulation
TK_Src_SrcA_SRC_Y	Q16832	DDR2	P12931	SRC	Y471	D472N	472	Missense	proximal	1	no	21.934	20.542	EPSD;PhosphoSitePlus	ICGC	20.673	Loss
TK_Src_SrcA_SRC_Y	Q16832	DDR2	P12931	SRC	Y481	L477I	477	Missense	distal	-4	no	21.232	20.794	EPSD	ICGC;COSMIC	20.673	Down-regulation
TK_Src_SrcA_SRC_Y	Q16832	DDR2	P12931	SRC	Y481	R478C	478	Missense	distal	-3	no	21.232	19.584	EPSD	ICGC;COSMIC	20.673	Loss
TK_Src_SrcA_SRC_Y	Q16832	DDR2	P12931	SRC	Y481	I488R	488	Missense	distal	7	no	21.232	21.230	EPSD	ICGC;COSMIC	20.673	Down-regulation
TK_Src_SrcA_SRC_Y	Q16832	DDR2	P12931	SRC	Y740	R746Q	746	Missense	distal	6	no	22.905	22.922	EPSD;PhosphoSitePlus	ICGC	20.673	Up-regulation
TK_Src_SrcA_SRC_Y	Q16832	DDR2	P12931	SRC	Y740	R733K	733	Missense	distal	-7	no	22.905	22.572	EPSD;PhosphoSitePlus	ICGC;COSMIC	20.673	Down-regulation
TK_Src_SrcA_SRC_Y	Q16832	DDR2	P12931	SRC	Y740	R746W	746	Missense	distal	6	no	22.905	23.008	EPSD;PhosphoSitePlus	ICGC;COSMIC	20.673	Up-regulation
TK_Src_SrcA_SRC_Y	Q16832	DDR2	P12931	SRC	Y740	R742Q	742	Missense	proximal	2	no	22.905	23.255	EPSD;PhosphoSitePlus	ICGC;COSMIC	20.673	Up-regulation
TK_Src_SrcA_SRC_Y	Q16832	DDR2	P12931	SRC	Y741	R746Q	746	Missense	distal	5	no	21.636	21.661	EPSD;PhosphoSitePlus	ICGC	20.673	Up-regulation
TK_Src_SrcA_SRC_Y	Q16832	DDR2	P12931	SRC	Y741	R746W	746	Missense	distal	5	no	21.636	22.228	EPSD;PhosphoSitePlus	ICGC;COSMIC	20.673	Up-regulation
TK_Src_SrcA_SRC_Y	Q16832	DDR2	P12931	SRC	Y741	R742Q	742	Missense	proximal	1	no	21.636	22.629	EPSD;PhosphoSitePlus	ICGC;COSMIC	20.673	Up-regulation
TK_Src_SrcA_SRC_Y	Q8N556	AFAP1	P12931	SRC	Y125	D131E	131	Missense	distal	6	no	21.006	21.056	EPSD;PhosphoSitePlus	ICGC;COSMIC	20.673	Up-regulation
TK_Src_SrcA_SRC_Y	Q8N556	AFAP1	P12931	SRC	Y125	D131G	131	Missense	distal	6	no	21.006	21.047	EPSD;PhosphoSitePlus	ICGC;COSMIC	20.673	Up-regulation
TK_Src_SrcA_SRC_Y	Q8N556	AFAP1	P12931	SRC	Y125	G132R	132	Missense	distal	7	no	21.006	21.013	EPSD;PhosphoSitePlus	ICGC;COSMIC	20.673	Up-regulation
TK_Src_SrcA_SRC_Y	Q8N556	AFAP1	P12931	SRC	Y501	T497A	497	Missense	distal	-4	no	21.075	20.800	EPSD	ICGC;COSMIC	20.673	Down-regulation
TK_Src_SrcA_SRC_Y	Q13322	GRB10	P12931	SRC	Y16	T23K	23	Missense	distal	7	no	20.861	20.903	EPSD	ICGC	20.673	Up-regulation
TK_Src_SrcA_SRC_Y	Q13322	GRB10	P12931	SRC	Y16	L11F	11	Missense	distal	-5	no	20.861	20.796	EPSD	ICGC;COSMIC	20.673	Down-regulation
TK_Src_SrcA_SRC_Y	Q13322	GRB10	P12931	SRC	Y67	A61T	61	Missense	distal	-6	no	21.316	21.353	PhosphoSitePlus	ICGC;COSMIC	20.673	Up-regulation
TK_Src_SrcA_SRC_Y	Q13435	SF3B2	P12931	SRC	Y379	T373S	373	Missense	distal	-6	no	24.933	24.985	PhosphoSitePlus;EPSD	ICGC;COSMIC	20.673	Up-regulation
TK_Src_SrcA_SRC_Y	Q13435	SF3B2	P12931	SRC	Y591	G594R	594	Missense	distal	3	no	23.212	21.927	EPSD	ICGC	20.673	Down-regulation
TK_Src_SrcA_SRC_Y	Q13435	SF3B2	P12931	SRC	Y592	G594R	594	Missense	proximal	2	no	20.654	20.951	EPSD;PhosphoSitePlus	ICGC	20.673	Gain
TK_Src_SrcA_SRC_Y	Q13435	SF3B2	P12931	SRC	Y645	R638Q	638	Missense	distal	-7	no	20.833	20.609	EPSD	ICGC	20.673	Loss
TK_Src_SrcA_SRC_Y	Q13435	SF3B2	P12931	SRC	Y645	P643L	643	Missense	proximal	-2	no	20.833	19.303	EPSD	ICGC;COSMIC	20.673	Loss
TK_Src_SrcA_SRC_Y	Q13435	SF3B2	P12931	SRC	Y645	P643S	643	Missense	proximal	-2	no	20.833	20.047	EPSD	ICGC;COSMIC	20.673	Loss
TK_Src_SrcA_SRC_Y	Q9NYF8	BCLAF1	P12931	SRC	Y81	G79W	79	Missense	proximal	-2	no	22.817	20.509	EPSD;PhosphoSitePlus	ICGC;COSMIC	20.673	Loss
TK_Src_SrcA_SRC_Y	Q9NYF8	BCLAF1	P12931	SRC	Y81	R74K	74	Missense	distal	-7	no	22.817	22.484	EPSD;PhosphoSitePlus	ICGC;COSMIC	20.673	Down-regulation
TK_Src_SrcA_SRC_Y	Q9NYF8	BCLAF1	P12931	SRC	Y150	S146T	146	Missense	distal	-4	no	21.992	21.872	EPSD;PhosphoSitePlus	ICGC;COSMIC	20.673	Down-regulation
TK_Src_SrcA_SRC_Y	Q9NYF8	BCLAF1	P12931	SRC	Y150	S146Y	146	Missense	distal	-4	no	21.992	21.946	EPSD;PhosphoSitePlus	ICGC;COSMIC	20.673	Down-regulation
TK_Src_SrcA_SRC_Y	Q9NYF8	BCLAF1	P12931	SRC	Y150	S148F	148	Missense	proximal	-2	no	21.992	21.012	EPSD;PhosphoSitePlus	ICGC	20.673	Down-regulation
TK_Src_SrcA_SRC_Y	Q9NYF8	BCLAF1	P12931	SRC	Y150	S146F	146	Missense	distal	-4	no	21.992	21.074	EPSD;PhosphoSitePlus	ICGC	20.673	Down-regulation
TK_Src_SrcA_SRC_Y	Q9NYF8	BCLAF1	P12931	SRC	Y284	S281Y	281	Missense	distal	-3	no	20.774	19.853	EPSD;PhosphoSitePlus	ICGC;COSMIC	20.673	Loss
TK_Src_SrcA_SRC_Y	Q9NYF8	BCLAF1	P12931	SRC	Y284	G278R	278	Missense	distal	-6	no	20.774	20.777	EPSD;PhosphoSitePlus	ICGC	20.673	Up-regulation
TK_Src_SrcA_SRC_Y	O15530	PDPK1	P12931	SRC	Y373	S366L	366	Missense	distal	-7	no	23.167	22.931	EPSD;PhosphoSitePlus	ICGC	20.673	Down-regulation
TK_Src_SrcA_SRC_Y	Q15654	TRIP6	P12931	SRC	Y55	E52D	52	Missense	distal	-3	no	23.771	23.817	PhosphoSitePlus	ICGC	20.673	Up-regulation
TK_Src_SrcA_SRC_Y	Q15654	TRIP6	P12931	SRC	Y55	G59W	59	Missense	distal	4	no	23.771	23.742	PhosphoSitePlus	ICGC;COSMIC	20.673	Down-regulation
TK_Src_SrcA_SRC_Y	Q15654	TRIP6	P12931	SRC	Y123	A122S	122	Missense	proximal	-1	no	23.813	23.702	EPSD	ICGC;COSMIC	20.673	Down-regulation
TK_Src_SrcA_SRC_Y	Q15654	TRIP6	P12931	SRC	Y123	Q121L	121	Missense	proximal	-2	no	23.813	23.069	EPSD	ICGC;COSMIC	20.673	Down-regulation
TK_Src_SrcA_SRC_Y	Q15654	TRIP6	P12931	SRC	Y123	R116Q	116	Missense	distal	-7	no	23.813	23.589	EPSD	ICGC	20.673	Down-regulation
TK_Src_SrcA_SRC_Y	Q15654	TRIP6	P12931	SRC	Y320	G316D	316	Missense	distal	-4	no	20.597	21.256	EPSD	ICGC;COSMIC	20.673	Gain
TK_Src_SrcA_SRC_Y	Q9Y613	FHOD1	P12931	SRC	Y439	R436M	436	Missense	distal	-3	no	20.937	20.071	EPSD	ICGC;COSMIC	20.673	Loss
TK_Src_SrcA_SRC_Y	Q9Y613	FHOD1	P12931	SRC	Y439	S434R	434	Missense	distal	-5	no	20.937	20.853	EPSD	ICGC;COSMIC	20.673	Down-regulation
TK_Src_SrcA_SRC_Y	Q9Y613	FHOD1	P12931	SRC	Y878	A883V	883	Missense	distal	5	no	23.528	23.670	EPSD	ICGC;COSMIC	20.673	Up-regulation
TK_Src_SrcA_SRC_Y	Q9Y613	FHOD1	P12931	SRC	Y878	S875Y	875	Missense	distal	-3	no	23.528	22.607	EPSD	ICGC;COSMIC	20.673	Down-regulation
TK_Src_SrcA_SRC_Y	Q9Y613	FHOD1	P12931	SRC	Y878	P872S	872	Missense	distal	-6	no	23.528	23.578	EPSD	ICGC	20.673	Up-regulation
TK_Src_SrcA_SRC_Y	P00533	EGFR	P12931	SRC	Y112	N115K	115	Missense	distal	3	no	22.347	20.030	EPSD	ICGC;COSMIC	20.673	Loss
TK_Src_SrcA_SRC_Y	P00533	EGFR	P12931	SRC	Y112	Y117C	117	Missense	distal	5	no	22.347	22.392	EPSD	ICGC;COSMIC	20.673	Up-regulation
TK_Src_SrcA_SRC_Y	P00533	EGFR	P12931	SRC	Y113	N115K	115	Missense	proximal	2	no	21.380	20.285	EPSD	ICGC;COSMIC	20.673	Loss
TK_Src_SrcA_SRC_Y	P00533	EGFR	P12931	SRC	Y113	Y117C	117	Missense	distal	4	no	21.380	21.390	EPSD	ICGC;COSMIC	20.673	Up-regulation
TK_Src_SrcA_SRC_Y	P00533	EGFR	P12931	SRC	Y869	L862M	862	Missense	distal	-7	no	21.933	21.627	EPSD;PhosphoSitePlus	ICGC;COSMIC	20.673	Down-regulation
TK_Src_SrcA_SRC_Y	P00533	EGFR	P12931	SRC	Y998	S991R	991	Missense	distal	-7	no	22.476	22.723	EPSD	ICGC;COSMIC	20.673	Up-regulation
TK_Src_SrcA_SRC_Y	P00533	EGFR	P12931	SRC	Y1125	A1118V	1118	Missense	distal	-7	no	24.203	24.255	EPSD;PhosphoSitePlus	ICGC;COSMIC	20.673	Up-regulation
TK_Src_SrcA_SRC_Y	P00533	EGFR	P12931	SRC	Y1172	D1168N	1168	Missense	distal	-4	no	22.551	22.019	EPSD	ICGC;COSMIC	20.673	Down-regulation
TK_Src_SrcA_SRC_Y	P00533	EGFR	P12931	SRC	Y1172	N1169S	1169	Missense	distal	-3	no	22.551	22.591	EPSD	ICGC	20.673	Up-regulation
TK_Src_SrcA_SRC_Y	P16662	UGT2B7	P12931	SRC	Y438	E440D	440	Missense	proximal	2	no	22.427	22.139	PhosphoSitePlus	ICGC	20.673	Down-regulation
TK_Src_SrcA_SRC_Y	P16662	UGT2B7	P12931	SRC	Y438	I433L	433	Missense	distal	-5	no	22.427	22.474	PhosphoSitePlus	ICGC	20.673	Up-regulation
TK_Src_SrcA_SRC_Y	P16662	UGT2B7	P12931	SRC	Y438	R431T	431	Missense	distal	-7	no	22.427	22.275	PhosphoSitePlus	ICGC;COSMIC	20.673	Down-regulation
TK_Src_SrcA_SRC_Y	O75955	FLOT1	P12931	SRC	Y238	A234T	234	Missense	distal	-4	no	20.515	20.790	EPSD	ICGC;COSMIC	20.673	Gain
TK_Src_SrcA_SRC_Y	P11413	G6PD	P12931	SRC	Y107	R104C	104	Missense	distal	-3	no	20.867	19.219	EPSD	ICGC;COSMIC	20.673	Loss
TK_Src_SrcA_SRC_Y	P11413	G6PD	P12931	SRC	Y107	D114G	114	Missense	distal	7	no	20.867	20.928	EPSD	ICGC;COSMIC	20.673	Up-regulation
TK_Src_SrcA_SRC_Y	P11413	G6PD	P12931	SRC	Y107	R104S	104	Missense	distal	-3	no	20.867	21.941	EPSD	ICGC;COSMIC	20.673	Up-regulation
TK_Src_SrcA_SRC_Y	P11413	G6PD	P12931	SRC	Y107	D100Y	100	Missense	distal	-7	no	20.867	20.417	EPSD	ICGC;COSMIC	20.673	Loss
TK_Src_SrcA_SRC_Y	P11413	G6PD	P12931	SRC	Y107	S106F	106	Missense	proximal	-1	no	20.867	20.345	EPSD	ICGC;COSMIC	20.673	Loss
TK_Src_SrcA_SRC_Y	P11413	G6PD	P12931	SRC	Y112	D114G	114	Missense	proximal	2	no	20.713	20.046	EPSD	ICGC;COSMIC	20.673	Loss
TK_Src_SrcA_SRC_Y	P11413	G6PD	P12931	SRC	Y112	S106F	106	Missense	distal	-6	no	20.713	20.577	EPSD	ICGC;COSMIC	20.673	Loss
TK_Src_SrcA_SRC_Y	P11413	G6PD	P12931	SRC	Y118	D114G	114	Missense	distal	-4	no	21.248	20.589	EPSD	ICGC;COSMIC	20.673	Loss
TK_Src_SrcA_SRC_Y	P11413	G6PD	P12931	SRC	Y118	R120S	120	Missense	proximal	2	no	21.248	22.079	EPSD	ICGC	20.673	Up-regulation
TK_Src_SrcA_SRC_Y	P11413	G6PD	P12931	SRC	Y118	N122K	122	Missense	distal	4	no	21.248	21.204	EPSD	ICGC;COSMIC	20.673	Down-regulation
TK_Src_SrcA_SRC_Y	P11413	G6PD	P12931	SRC	Y118	M125I	125	Missense	distal	7	no	21.248	21.221	EPSD	ICGC	20.673	Down-regulation
TK_Src_SrcA_SRC_Y	P11413	G6PD	P12931	SRC	Y147	V150I	150	Missense	distal	3	no	22.865	22.805	EPSD	ICGC;COSMIC	20.673	Down-regulation
TK_Src_SrcA_SRC_Y	P11413	G6PD	P12931	SRC	Y147	A149V	149	Missense	proximal	2	no	22.865	23.076	EPSD	ICGC;COSMIC	20.673	Up-regulation
TK_Src_SrcA_SRC_Y	P11413	G6PD	P12931	SRC	Y147	A149D	149	Missense	proximal	2	no	22.865	22.757	EPSD	ICGC;COSMIC	20.673	Down-regulation
TK_Src_SrcA_SRC_Y	P11413	G6PD	P12931	SRC	Y428	R427T	427	Missense	proximal	-1	no	20.250	21.659	EPSD;PhosphoSitePlus	ICGC;COSMIC	20.673	Gain
TK_Src_SrcA_SRC_Y	Q15691	MAPRE1	P12931	SRC	Y124	D123H	123	Missense	proximal	-1	no	20.498	21.065	EPSD	ICGC;COSMIC	20.673	Gain
TK_Src_SrcA_SRC_Y	P12931	SRC	P12931	SRC	Y338	V340I	340	Missense	proximal	2	no	23.077	21.882	EPSD;PhosphoSitePlus	ICGC;COSMIC	20.673	Down-regulation
TK_Src_SrcA_SRC_Y	P12931	SRC	P12931	SRC	Y419	G424C	424	Missense	distal	5	no	24.549	24.801	EPSD;PhosphoSitePlus	ICGC;COSMIC	20.673	Up-regulation
TK_Src_SrcA_SRC_Y	P12931	SRC	P12931	SRC	Y419	R422W	422	Missense	distal	3	no	24.549	24.452	EPSD;PhosphoSitePlus	ICGC	20.673	Down-regulation
TK_Src_SrcA_SRC_Y	P33151	CDH5	P12931	SRC	Y685	R681Q	681	Missense	distal	-4	no	21.644	21.265	EPSD;PhosphoSitePlus	ICGC;COSMIC	20.673	Down-regulation
TK_Src_SrcA_SRC_Y	P33151	CDH5	P12931	SRC	Y685	R681W	681	Missense	distal	-4	no	21.644	20.271	EPSD;PhosphoSitePlus	ICGC;COSMIC	20.673	Loss
TK_Src_SrcA_SRC_Y	P33151	CDH5	P12931	SRC	Y685	R681L	681	Missense	distal	-4	no	21.644	20.686	EPSD;PhosphoSitePlus	ICGC	20.673	Down-regulation
TK_Src_SrcA_SRC_Y	P33151	CDH5	P12931	SRC	Y685	P692Q	692	Missense	distal	7	no	21.644	21.619	EPSD;PhosphoSitePlus	ICGC;COSMIC	20.673	Down-regulation
TK_Src_SrcA_SRC_Y	P33151	CDH5	P12931	SRC	Y685	P691Q	691	Missense	distal	6	no	21.644	21.639	EPSD;PhosphoSitePlus	ICGC;COSMIC	20.673	Down-regulation
TK_Src_SrcA_SRC_Y	P33151	CDH5	P12931	SRC	Y725	D721N	721	Missense	distal	-4	no	24.899	24.366	EPSD	ICGC;COSMIC	20.673	Down-regulation
TK_Src_SrcA_SRC_Y	P33151	CDH5	P12931	SRC	Y731	S738F	738	Missense	distal	7	no	21.971	21.998	PhosphoSitePlus;EPSD	ICGC	20.673	Up-regulation
TK_Src_SrcA_SRC_Y	Q92556	ELMO1	P12931	SRC	Y395	R397W	397	Missense	proximal	2	no	20.907	21.264	EPSD	ICGC;COSMIC	20.673	Up-regulation
TK_Src_SrcA_SRC_Y	Q92556	ELMO1	P12931	SRC	Y395	K389R	389	Missense	distal	-6	no	20.907	20.693	EPSD	ICGC	20.673	Down-regulation
TK_Src_SrcA_SRC_Y	Q92556	ELMO1	P12931	SRC	Y395	N402K	402	Missense	distal	7	no	20.907	20.952	EPSD	ICGC	20.673	Up-regulation
TK_Src_SrcA_SRC_Y	Q92556	ELMO1	P12931	SRC	Y395	A388V	388	Missense	distal	-7	no	20.907	20.959	EPSD	ICGC;COSMIC	20.673	Up-regulation
TK_Src_SrcA_SRC_Y	Q92556	ELMO1	P12931	SRC	Y588	K584N	584	Missense	distal	-4	no	21.554	22.418	EPSD	ICGC;COSMIC	20.673	Up-regulation
TK_Src_SrcA_SRC_Y	Q92556	ELMO1	P12931	SRC	Y588	H583R	583	Missense	distal	-5	no	21.554	21.345	EPSD	ICGC	20.673	Down-regulation
TK_Src_SrcA_SRC_Y	Q92556	ELMO1	P12931	SRC	Y588	P581A	581	Missense	distal	-7	no	21.554	21.351	EPSD	ICGC	20.673	Down-regulation
TK_Src_SrcA_SRC_Y	Q92556	ELMO1	P12931	SRC	Y588	P595T	595	Missense	distal	7	no	21.554	21.504	EPSD	ICGC;COSMIC	20.673	Down-regulation
TK_Src_SrcA_SRC_Y	Q92556	ELMO1	P12931	SRC	Y588	D590E	590	Missense	proximal	2	no	21.554	21.842	EPSD	ICGC;COSMIC	20.673	Up-regulation
TK_Src_SrcA_SRC_Y	Q92556	ELMO1	P12931	SRC	Y588	H583Q	583	Missense	distal	-5	no	21.554	21.186	EPSD	ICGC;COSMIC	20.673	Down-regulation
TK_Src_SrcA_SRC_Y	Q92556	ELMO1	P12931	SRC	Y588	P581L	581	Missense	distal	-7	no	21.554	21.439	EPSD	ICGC;COSMIC	20.673	Down-regulation
TK_Src_SrcA_SRC_Y	Q92556	ELMO1	P12931	SRC	Y724	C726R	726	Missense	proximal	2	no	20.794	21.394	EPSD;PhosphoSitePlus	ICGC;COSMIC	20.673	Up-regulation
TK_Src_SrcA_SRC_Y	Q92556	ELMO1	P12931	SRC	Y724	Y720C	720	Missense	distal	-4	no	20.794	19.511	EPSD;PhosphoSitePlus	ICGC	20.673	Loss
TK_Src_SrcA_SRC_Y	P46934	NEDD4	P12931	SRC	Y412	N407H	407	Missense	distal	-5	no	20.940	21.194	EPSD	ICGC;COSMIC	20.673	Up-regulation
TK_Src_SrcA_SRC_Y	P46934	NEDD4	P12931	SRC	Y412	T419A	419	Missense	distal	7	no	20.940	20.960	EPSD	ICGC	20.673	Up-regulation
TK_Src_SrcA_SRC_Y	P46934	NEDD4	P12931	SRC	Y1004	A1008V	1008	Missense	distal	4	no	21.103	21.077	EPSD	ICGC	20.673	Down-regulation
TK_Src_SrcA_SRC_Y	P46934	NEDD4	P12931	SRC	Y1004	A1008D	1008	Missense	distal	4	no	21.103	21.121	EPSD	ICGC	20.673	Up-regulation
TK_Src_SrcA_SRC_Y	P46934	NEDD4	P12931	SRC	Y1004	L1002M	1002	Missense	proximal	-2	no	21.103	20.513	EPSD	ICGC;COSMIC	20.673	Loss
TK_Src_SrcA_SRC_Y	P51812	RPS6KA3	P12931	SRC	Y483	K480N	480	Missense	distal	-3	no	23.207	24.455	EPSD;PhosphoSitePlus	ICGC;COSMIC	20.673	Up-regulation
TK_Src_SrcA_SRC_Y	P51812	RPS6KA3	P12931	SRC	Y580	M576T	576	Missense	distal	-4	no	20.136	20.970	EPSD;PhosphoSitePlus	ICGC;COSMIC	20.673	Gain
TK_Src_SrcA_SRC_Y	Q05397	PTK2	P12931	SRC	Y194	A187T	187	Missense	distal	-7	no	20.702	21.122	EPSD;PhosphoSitePlus	ICGC;COSMIC	20.673	Up-regulation
TK_Src_SrcA_SRC_Y	Q05397	PTK2	P12931	SRC	Y441	D435N	435	Missense	distal	-6	no	21.321	21.131	EPSD;PhosphoSitePlus	ICGC;COSMIC	20.673	Down-regulation
TK_Src_SrcA_SRC_Y	Q05397	PTK2	P12931	SRC	Y441	H437N	437	Missense	distal	-4	no	21.321	21.949	EPSD;PhosphoSitePlus	ICGC	20.673	Up-regulation
TK_Src_SrcA_SRC_Y	Q05397	PTK2	P12931	SRC	Y861	P854L	854	Missense	distal	-7	no	23.332	23.217	EPSD;PhosphoSitePlus	ICGC;COSMIC	20.673	Down-regulation
TK_Src_SrcA_SRC_Y	Q05397	PTK2	P12931	SRC	Y861	H859Y	859	Missense	proximal	-2	no	23.332	22.664	EPSD;PhosphoSitePlus	ICGC;COSMIC	20.673	Down-regulation
TK_Src_SrcA_SRC_Y	Q05397	PTK2	P12931	SRC	Y898	S897Y	897	Missense	proximal	-1	no	20.350	21.526	EPSD;PhosphoSitePlus	ICGC	20.673	Gain
TK_Src_SrcA_SRC_Y	P07355	ANXA2	P12931	SRC	Y24	T19A	19	Missense	distal	-5	no	22.045	22.255	PhosphoSitePlus	ICGC;COSMIC	20.673	Up-regulation
TK_Src_SrcA_SRC_Y	P07355	ANXA2	P12931	SRC	Y24	S18C	18	Missense	distal	-6	no	22.045	21.507	PhosphoSitePlus	ICGC;COSMIC	20.673	Down-regulation
TK_Src_SrcA_SRC_Y	P07355	ANXA2	P12931	SRC	Y24	Y30C	30	Missense	distal	6	no	22.045	22.086	PhosphoSitePlus	ICGC;COSMIC	20.673	Up-regulation
TK_Src_SrcA_SRC_Y	P07355	ANXA2	P12931	SRC	Y24	P21T	21	Missense	distal	-3	no	22.045	22.452	PhosphoSitePlus	ICGC;COSMIC	20.673	Up-regulation
TK_Src_SrcA_SRC_Y	P07355	ANXA2	P12931	SRC	Y24	S18F	18	Missense	distal	-6	no	22.045	21.908	PhosphoSitePlus	ICGC	20.673	Down-regulation
TK_Src_SrcA_SRC_Y	P07355	ANXA2	P12931	SRC	Y188	A195D	195	Missense	distal	7	no	21.347	21.327	EPSD	ICGC;COSMIC	20.673	Down-regulation
TK_Src_SrcA_SRC_Y	P07355	ANXA2	P12931	SRC	Y235	S236N	236	Missense	proximal	1	no	21.536	20.636	EPSD	ICGC;COSMIC	20.673	Loss
TK_Src_SrcA_SRC_Y	P07355	ANXA2	P12931	SRC	Y235	D230H	230	Missense	distal	-5	no	21.536	21.577	EPSD	ICGC;COSMIC	20.673	Up-regulation
TK_Src_SrcA_SRC_Y	P07355	ANXA2	P12931	SRC	Y235	P237H	237	Missense	proximal	2	no	21.536	21.160	EPSD	ICGC;COSMIC	20.673	Down-regulation
TK_Src_SrcA_SRC_Y	P07355	ANXA2	P12931	SRC	Y235	R231M	231	Missense	distal	-4	no	21.536	20.312	EPSD	ICGC;COSMIC	20.673	Loss
TK_Src_SrcA_SRC_Y	P07355	ANXA2	P12931	SRC	Y235	M240T	240	Missense	distal	5	no	21.536	21.314	EPSD	ICGC;COSMIC	20.673	Down-regulation
TK_Src_SrcA_SRC_Y	P07355	ANXA2	P12931	SRC	Y238	S236N	236	Missense	proximal	-2	no	21.411	22.033	EPSD	ICGC;COSMIC	20.673	Up-regulation
TK_Src_SrcA_SRC_Y	P07355	ANXA2	P12931	SRC	Y238	R245S	245	Missense	distal	7	no	21.411	21.373	EPSD	ICGC	20.673	Down-regulation
TK_Src_SrcA_SRC_Y	P07355	ANXA2	P12931	SRC	Y238	P237H	237	Missense	proximal	-1	no	21.411	21.640	EPSD	ICGC;COSMIC	20.673	Up-regulation
TK_Src_SrcA_SRC_Y	P07355	ANXA2	P12931	SRC	Y238	R231M	231	Missense	distal	-7	no	21.411	20.621	EPSD	ICGC;COSMIC	20.673	Loss
TK_Src_SrcA_SRC_Y	P07355	ANXA2	P12931	SRC	Y238	M240T	240	Missense	proximal	2	no	21.411	21.559	EPSD	ICGC;COSMIC	20.673	Up-regulation
TK_Src_SrcA_SRC_Y	P07355	ANXA2	P12931	SRC	Y275	R273W	273	Missense	proximal	-2	no	21.450	20.500	EPSD	ICGC;COSMIC	20.673	Loss
TK_Src_SrcA_SRC_Y	P07355	ANXA2	P12931	SRC	Y275	G280D	280	Missense	distal	5	no	21.450	21.086	EPSD	ICGC	20.673	Down-regulation
TK_Src_SrcA_SRC_Y	P07355	ANXA2	P12931	SRC	Y275	Y269H	269	Missense	distal	-6	no	21.450	21.281	EPSD	ICGC;COSMIC	20.673	Down-regulation
TK_Src_SrcA_SRC_Y	P07355	ANXA2	P12931	SRC	Y316	Y311H	311	Missense	distal	-5	no	20.095	20.761	EPSD	ICGC	20.673	Gain
TK_Src_SrcA_SRC_Y	P35228	NOS2	P12931	SRC	Y46	L49F	49	Missense	distal	3	no	20.974	21.214	EPSD	ICGC	20.673	Up-regulation
TK_Src_SrcA_SRC_Y	P35228	NOS2	P12931	SRC	Y46	Q45K	45	Missense	proximal	-1	no	20.974	19.471	EPSD	ICGC	20.673	Loss
TK_Src_SrcA_SRC_Y	P35228	NOS2	P12931	SRC	Y151	Q149K	149	Missense	proximal	-2	no	22.633	22.463	EPSD;PhosphoSitePlus	ICGC;COSMIC	20.673	Down-regulation
TK_Src_SrcA_SRC_Y	P35228	NOS2	P12931	SRC	Y270	Y267N	267	Missense	distal	-3	no	20.248	21.129	EPSD	ICGC;COSMIC	20.673	Gain
TK_Src_SrcA_SRC_Y	P35228	NOS2	P12931	SRC	Y1123	R1122L	1122	Missense	proximal	-1	no	19.538	21.190	EPSD	ICGC;COSMIC	20.673	Gain
TK_Src_SrcA_SRC_Y	O00560	SDCBP	P12931	SRC	Y46	P47S	47	Missense	proximal	1	no	20.265	22.410	EPSD;PhosphoSitePlus	ICGC;COSMIC	20.673	Gain
TK_Src_SrcA_SRC_Y	Q9ULV8	CBLC	P12931	SRC	Y402	H405N	405	Missense	distal	3	no	20.001	20.798	EPSD	ICGC;COSMIC	20.673	Gain
TK_Src_SrcA_SRC_Y	Q92734	TFG	P12931	SRC	Y33	M40I	40	Missense	distal	7	no	23.856	23.829	PhosphoSitePlus;EPSD	ICGC	20.673	Down-regulation
TK_Src_SrcA_SRC_Y	P35579	MYH9	P12931	SRC	Y1861	A1858S	1858	Missense	distal	-3	no	20.211	21.116	EPSD	ICGC;COSMIC	20.673	Gain
TK_Src_SrcA_SRC_Y	Q9BXP5	SRRT	P12931	SRC	Y8	D14V	14	Missense	distal	6	no	21.784	21.819	EPSD	ICGC;COSMIC	20.673	Up-regulation
TK_Src_SrcA_SRC_Y	Q9BXP5	SRRT	P12931	SRC	Y8	S4I	4	Missense	distal	-4	no	21.784	20.658	EPSD	ICGC	20.673	Loss
TK_Src_SrcA_SRC_Y	Q9BXP5	SRRT	P12931	SRC	Y8	K15T	15	Missense	distal	7	no	21.784	21.742	EPSD	ICGC;COSMIC	20.673	Down-regulation
TK_Src_SrcA_SRC_Y	Q9BXP5	SRRT	P12931	SRC	Y23	R29I	29	Missense	distal	6	no	21.701	21.726	EPSD	ICGC;COSMIC	20.673	Up-regulation
TK_Src_SrcA_SRC_Y	Q9BXP5	SRRT	P12931	SRC	Y23	S21R	21	Missense	proximal	-2	no	21.701	20.955	EPSD	ICGC	20.673	Down-regulation
TK_Src_SrcA_SRC_Y	Q9BXP5	SRRT	P12931	SRC	Y55	R56L	56	Missense	proximal	1	no	22.374	21.707	EPSD	ICGC	20.673	Down-regulation
TK_Src_SrcA_SRC_Y	Q9BXP5	SRRT	P12931	SRC	Y55	R49C	49	Missense	distal	-6	no	22.374	21.977	EPSD	ICGC;COSMIC	20.673	Down-regulation
TK_Src_SrcA_SRC_Y	Q9BXP5	SRRT	P12931	SRC	Y58	R56L	56	Missense	proximal	-2	no	21.327	21.328	EPSD	ICGC	20.673	Up-regulation
TK_Src_SrcA_SRC_Y	Q9BXP5	SRRT	P12931	SRC	Y58	R65H	65	Missense	distal	7	no	21.327	21.314	EPSD	ICGC;COSMIC	20.673	Down-regulation
TK_Src_SrcA_SRC_Y	Q9BXP5	SRRT	P12931	SRC	Y836	G843W	843	Missense	distal	7	no	21.974	22.078	EPSD;PhosphoSitePlus	ICGC	20.673	Up-regulation
TK_Src_SrcA_SRC_Y	Q9BXP5	SRRT	P12931	SRC	Y836	G830W	830	Missense	distal	-6	no	21.974	21.709	EPSD;PhosphoSitePlus	ICGC;COSMIC	20.673	Down-regulation
TK_Src_SrcA_SRC_Y	Q96TC7	RMDN3	P12931	SRC	Y53	D52E	52	Missense	proximal	-1	no	21.617	22.527	EPSD	ICGC	20.673	Up-regulation
TK_Src_SrcA_SRC_Y	Q96TC7	RMDN3	P12931	SRC	Y176	A179S	179	Missense	distal	3	no	21.241	21.197	PhosphoSitePlus	ICGC	20.673	Down-regulation
TK_Src_SrcA_SRC_Y	P19367	HK1	P12931	SRC	Y27	R30H	30	Missense	distal	3	no	20.086	21.276	EPSD	ICGC;COSMIC	20.673	Gain
TK_Src_SrcA_SRC_Y	Q14247	CTTN	P12931	SRC	Y154	G160S	160	Missense	distal	6	no	21.047	21.027	EPSD	ICGC;COSMIC	20.673	Down-regulation
TK_Src_SrcA_SRC_Y	Q14247	CTTN	P12931	SRC	Y421	L415P	415	Missense	distal	-6	no	23.528	23.548	EPSD	ICGC	20.673	Up-regulation
TK_Src_SrcA_SRC_Y	Q14247	CTTN	P12931	SRC	Y421	A424V	424	Missense	distal	3	no	23.528	24.098	EPSD	ICGC;COSMIC;GDSC	20.673	Up-regulation
TK_Src_SrcA_SRC_Y	Q14247	CTTN	P12931	SRC	Y446	A450G	450	Missense	distal	4	no	24.431	24.408	EPSD	ICGC;COSMIC	20.673	Down-regulation
TK_Src_SrcA_SRC_Y	Q14247	CTTN	P12931	SRC	Y446	T440M	440	Missense	distal	-6	no	24.431	23.942	EPSD	ICGC	20.673	Down-regulation
TK_Src_SrcA_SRC_Y	Q14247	CTTN	P12931	SRC	Y446	E441D	441	Missense	distal	-5	no	24.431	24.331	EPSD	ICGC	20.673	Down-regulation
TK_Src_SrcA_SRC_Y	Q14247	CTTN	P12931	SRC	Y446	A450V	450	Missense	distal	4	no	24.431	24.404	EPSD	ICGC;COSMIC	20.673	Down-regulation
TK_Src_SrcA_SRC_Y	Q14247	CTTN	P12931	SRC	Y464	L462Q	462	Missense	proximal	-2	no	21.253	21.997	EPSD	ICGC	20.673	Up-regulation
TK_Src_SrcA_SRC_Y	Q14247	CTTN	P12931	SRC	Y464	A463P	463	Missense	proximal	-1	no	21.253	21.493	EPSD	ICGC;COSMIC	20.673	Up-regulation
TK_Src_SrcA_SRC_Y	Q14247	CTTN	P12931	SRC	Y464	G461S	461	Missense	distal	-3	no	21.253	21.434	EPSD	ICGC;COSMIC	20.673	Up-regulation
TK_Src_SrcA_SRC_Y	Q14247	CTTN	P12931	SRC	Y470	A463P	463	Missense	distal	-7	no	24.053	24.256	EPSD;PhosphoSitePlus	ICGC;COSMIC	20.673	Up-regulation
TK_Src_SrcA_SRC_Y	Q14247	CTTN	P12931	SRC	Y470	P476S	476	Missense	distal	6	no	24.053	24.037	EPSD;PhosphoSitePlus	ICGC;COSMIC	20.673	Down-regulation
TK_Src_SrcA_SRC_Y	Q14247	CTTN	P12931	SRC	Y486	D483N	483	Missense	distal	-3	no	23.323	22.815	PhosphoSitePlus;EPSD	ICGC;COSMIC	20.673	Down-regulation
TK_Src_SrcA_SRC_Y	Q14247	CTTN	P12931	SRC	Y486	D487N	487	Missense	proximal	1	no	23.323	21.931	PhosphoSitePlus;EPSD	ICGC;COSMIC;GDSC	20.673	Down-regulation
TK_Src_SrcA_SRC_Y	Q14247	CTTN	P12931	SRC	Y486	P480A	480	Missense	distal	-6	no	23.323	23.283	PhosphoSitePlus;EPSD	ICGC;COSMIC	20.673	Down-regulation
TK_Src_SrcA_SRC_Y	Q14247	CTTN	P12931	SRC	Y486	D492Y	492	Missense	distal	6	no	23.323	23.378	PhosphoSitePlus;EPSD	ICGC;COSMIC	20.673	Up-regulation
TK_Src_SrcA_SRC_Y	Q14247	CTTN	P12931	SRC	Y486	D492H	492	Missense	distal	6	no	23.323	23.367	PhosphoSitePlus;EPSD	ICGC;COSMIC	20.673	Up-regulation
TK_Src_SrcA_SRC_Y	Q14247	CTTN	P12931	SRC	Y486	P480S	480	Missense	distal	-6	no	23.323	23.372	PhosphoSitePlus;EPSD	ICGC;COSMIC	20.673	Up-regulation
TK_Src_SrcA_SRC_Y	Q14247	CTTN	P12931	SRC	Y486	L493M	493	Missense	distal	7	no	23.323	23.376	PhosphoSitePlus;EPSD	ICGC;COSMIC	20.673	Up-regulation
TK_Src_SrcA_SRC_Y	Q9UGK3	STAP2	P12931	SRC	Y250	E248G	248	Missense	proximal	-2	no	22.925	22.348	PhosphoSitePlus;EPSD	ICGC;COSMIC	20.673	Down-regulation
TK_Src_SrcA_SRC_Y	Q9UGK3	STAP2	P12931	SRC	Y250	Y256F	256	Missense	distal	6	no	22.925	22.923	PhosphoSitePlus;EPSD	ICGC	20.673	Down-regulation
TK_Src_SrcA_SRC_Y	Q9UGK3	STAP2	P12931	SRC	Y250	K252N	252	Missense	proximal	2	no	22.925	24.021	PhosphoSitePlus;EPSD	ICGC;COSMIC	20.673	Up-regulation
TK_Src_SrcA_SRC_Y	Q9UGK3	STAP2	P12931	SRC	Y250	L245M	245	Missense	distal	-5	no	22.925	22.767	PhosphoSitePlus;EPSD	ICGC	20.673	Down-regulation
TK_Src_SrcA_SRC_Y	Q9UGK3	STAP2	P12931	SRC	Y310	N309T	309	Missense	proximal	-1	no	23.487	24.517	EPSD	ICGC;COSMIC	20.673	Up-regulation
TK_Src_SrcA_SRC_Y	Q96P31	FCRL3	P12931	SRC	Y133	Q130R	130	Missense	distal	-3	no	21.037	20.421	EPSD	ICGC;COSMIC	20.673	Loss
TK_Src_SrcA_SRC_Y	Q96P31	FCRL3	P12931	SRC	Y133	K131T	131	Missense	proximal	-2	no	21.037	20.969	EPSD	ICGC;COSMIC	20.673	Down-regulation
TK_Src_SrcA_SRC_Y	Q96P31	FCRL3	P12931	SRC	Y133	Y134F	134	Missense	proximal	1	no	21.037	19.066	EPSD	ICGC;COSMIC	20.673	Loss
TK_Src_SrcA_SRC_Y	Q96P31	FCRL3	P12931	SRC	Y133	K131N	131	Missense	proximal	-2	no	21.037	21.830	EPSD	ICGC;COSMIC	20.673	Up-regulation
TK_Src_SrcA_SRC_Y	Q96P31	FCRL3	P12931	SRC	Y662	G656A	656	Missense	distal	-6	no	21.137	21.190	EPSD;PhosphoSitePlus	ICGC;COSMIC	20.673	Up-regulation
TK_Src_SrcA_SRC_Y	Q96P31	FCRL3	P12931	SRC	Y662	Q669H	669	Missense	distal	7	no	21.137	21.166	EPSD;PhosphoSitePlus	ICGC;COSMIC	20.673	Up-regulation
TK_Src_SrcA_SRC_Y	Q96P31	FCRL3	P12931	SRC	Y662	G656E	656	Missense	distal	-6	no	21.137	21.366	EPSD;PhosphoSitePlus	ICGC	20.673	Up-regulation
TK_Src_SrcA_SRC_Y	Q96P31	FCRL3	P12931	SRC	Y662	W666L	666	Missense	distal	4	no	21.137	21.198	EPSD;PhosphoSitePlus	ICGC;COSMIC	20.673	Up-regulation
TK_Src_SrcA_SRC_Y	Q96P31	FCRL3	P12931	SRC	Y722	N721S	721	Missense	proximal	-1	no	22.894	23.830	PhosphoSitePlus;EPSD	ICGC;COSMIC	20.673	Up-regulation
TK_Src_SrcA_SRC_Y	Q13642	FHL1	P12931	SRC	Y149	D147E	147	Missense	proximal	-2	no	20.765	21.052	EPSD;PhosphoSitePlus	ICGC;COSMIC	20.673	Up-regulation
TK_Src_SrcA_SRC_Y	Q13642	FHL1	P12931	SRC	Y149	V151M	151	Missense	proximal	2	no	20.765	20.499	EPSD;PhosphoSitePlus	ICGC;COSMIC	20.673	Loss
TK_Src_SrcA_SRC_Y	Q13642	FHL1	P12931	SRC	Y149	P143T	143	Missense	distal	-6	no	20.765	20.762	EPSD;PhosphoSitePlus	ICGC;COSMIC	20.673	Down-regulation
TK_Src_SrcA_SRC_Y	Q13642	FHL1	P12931	SRC	Y207	C209Y	209	Missense	proximal	2	no	21.325	22.316	EPSD	ICGC;COSMIC	20.673	Up-regulation
TK_Src_SrcA_SRC_Y	Q13642	FHL1	P12931	SRC	Y207	Q206L	206	Missense	proximal	-1	no	21.325	21.146	EPSD	ICGC;COSMIC	20.673	Down-regulation
TK_Src_SrcA_SRC_Y	Q13642	FHL1	P12931	SRC	Y208	C209Y	209	Missense	proximal	1	no	22.496	24.772	EPSD	ICGC;COSMIC	20.673	Up-regulation
TK_Src_SrcA_SRC_Y	Q13642	FHL1	P12931	SRC	Y208	Q206L	206	Missense	proximal	-2	no	22.496	21.751	EPSD	ICGC;COSMIC	20.673	Down-regulation
TK_Src_SrcA_SRC_Y	P35222	CTNNB1	P12931	SRC	Y333	T332N	332	Missense	proximal	-1	no	22.219	21.189	PhosphoSitePlus;EPSD	ICGC;COSMIC	20.673	Down-regulation
TK_Src_SrcA_SRC_Y	P35222	CTNNB1	P12931	SRC	Y716	R710H	710	Missense	distal	-6	no	21.309	21.277	EPSD	ICGC;COSMIC	20.673	Down-regulation
TK_Src_SrcA_SRC_Y	O15162	PLSCR1	P12931	SRC	Y74	A81V	81	Missense	distal	7	no	22.539	22.615	EPSD;PhosphoSitePlus	ICGC;COSMIC	20.673	Up-regulation
TK_Src_SrcA_SRC_Y	P01889	HLA-B	P12931	SRC	Y344	C349S	349	Missense	distal	5	no	21.507	21.049	PhosphoSitePlus	ICGC	20.673	Down-regulation
TK_Src_SrcA_SRC_Y	P01889	HLA-B	P12931	SRC	Y344	G338R	338	Missense	distal	-6	no	21.507	21.510	PhosphoSitePlus	ICGC;COSMIC	20.673	Up-regulation
TK_Src_SrcA_SRC_Y	Q9Y3Q4	HCN4	P12931	SRC	Y506	V501M	501	Missense	distal	-5	no	22.963	22.644	EPSD	ICGC;COSMIC	20.673	Down-regulation
TK_Src_SrcA_SRC_Y	Q9Y3Q4	HCN4	P12931	SRC	Y506	H512Q	512	Missense	distal	6	no	22.963	22.951	EPSD	ICGC	20.673	Down-regulation
TK_Src_SrcA_SRC_Y	Q9Y3Q4	HCN4	P12931	SRC	Y506	H512N	512	Missense	distal	6	no	22.963	22.922	EPSD	ICGC	20.673	Down-regulation
TK_Src_SrcA_SRC_Y	Q9Y3Q4	HCN4	P12931	SRC	Y531	R525C	525	Missense	distal	-6	no	21.210	20.813	PhosphoSitePlus	ICGC;COSMIC	20.673	Down-regulation
TK_Src_SrcA_SRC_Y	Q9Y3Q4	HCN4	P12931	SRC	Y531	V534M	534	Missense	distal	3	no	21.210	20.844	PhosphoSitePlus	ICGC;COSMIC	20.673	Down-regulation
TK_Src_SrcA_SRC_Y	Q9Y3Q4	HCN4	P12931	SRC	Y537	F540L	540	Missense	distal	3	no	21.034	20.794	EPSD	ICGC	20.673	Down-regulation
TK_Src_SrcA_SRC_Y	Q9Y3Q4	HCN4	P12931	SRC	Y537	V534M	534	Missense	distal	-3	no	21.034	20.551	EPSD	ICGC;COSMIC	20.673	Loss
TK_Src_SrcA_SRC_Y	P49279	SLC11A1	P12931	SRC	Y15	P21S	21	Missense	distal	6	no	23.138	23.122	PhosphoSitePlus	ICGC;COSMIC	20.673	Down-regulation
TK_Src_SrcA_SRC_Y	P49279	SLC11A1	P12931	SRC	Y15	T22A	22	Missense	distal	7	no	23.138	23.157	PhosphoSitePlus	ICGC	20.673	Up-regulation
TK_Src_SrcA_SRC_Y	P01111	NRAS	P12931	SRC	Y32	N26S	26	Missense	distal	-6	no	20.815	20.841	PhosphoSitePlus	ICGC	20.673	Up-regulation
TK_Src_SrcA_SRC_Y	P01111	NRAS	P12931	SRC	Y32	D33H	33	Missense	proximal	1	no	20.815	19.370	PhosphoSitePlus	ICGC;COSMIC	20.673	Loss
TK_Src_SrcA_SRC_Y	P01111	NRAS	P12931	SRC	Y64	Q61P	61	Missense	distal	-3	no	23.002	22.342	EPSD	ICGC;COSMIC;CCLE	20.673	Down-regulation
TK_Src_SrcA_SRC_Y	P01111	NRAS	P12931	SRC	Y64	E63Q	63	Missense	proximal	-1	no	23.002	22.596	EPSD	ICGC;COSMIC	20.673	Down-regulation
TK_Src_SrcA_SRC_Y	P01111	NRAS	P12931	SRC	Y64	A66D	66	Missense	proximal	2	no	23.002	22.894	EPSD	ICGC;COSMIC	20.673	Down-regulation
TK_Src_SrcA_SRC_Y	P01111	NRAS	P12931	SRC	Y64	A59T	59	Missense	distal	-5	no	23.002	22.792	EPSD	ICGC;COSMIC	20.673	Down-regulation
TK_Src_SrcA_SRC_Y	Q9NZQ3	NCKIPSD	P12931	SRC	Y85	E88Q	88	Missense	distal	3	no	20.967	20.373	EPSD	ICGC;COSMIC	20.673	Loss
TK_Src_SrcA_SRC_Y	Q9NZQ3	NCKIPSD	P12931	SRC	Y85	S86R	86	Missense	proximal	1	no	20.967	20.088	EPSD	ICGC	20.673	Loss
TK_Src_SrcA_SRC_Y	Q9NZQ3	NCKIPSD	P12931	SRC	Y227	S222N	222	Missense	distal	-5	no	21.295	21.167	PhosphoSitePlus;EPSD	ICGC;COSMIC	20.673	Down-regulation
TK_Src_SrcA_SRC_Y	Q68CZ2	TNS3	P12931	SRC	Y549	G556E	556	Missense	distal	7	no	21.183	21.160	EPSD	ICGC;COSMIC	20.673	Down-regulation
TK_Src_SrcA_SRC_Y	Q68CZ2	TNS3	P12931	SRC	Y549	G547S	547	Missense	proximal	-2	no	21.183	20.571	EPSD	ICGC;COSMIC	20.673	Loss
TK_Src_SrcA_SRC_Y	P46937	YAP1	P12931	SRC	Y391	R394Q	394	Missense	distal	3	no	21.123	21.535	EPSD	ICGC;COSMIC	20.673	Up-regulation
TK_Src_SrcA_SRC_Y	P46937	YAP1	P12931	SRC	Y391	S397I	397	Missense	distal	6	no	21.123	21.143	EPSD	ICGC	20.673	Up-regulation
TK_Src_SrcA_SRC_Y	P46937	YAP1	P12931	SRC	Y391	F385S	385	Missense	distal	-6	no	21.123	21.259	EPSD	ICGC	20.673	Up-regulation
TK_Src_SrcA_SRC_Y	P46937	YAP1	P12931	SRC	Y391	H392N	392	Missense	proximal	1	no	21.123	21.176	EPSD	ICGC;COSMIC	20.673	Up-regulation
TK_Src_SrcA_SRC_Y	P46937	YAP1	P12931	SRC	Y391	T398A	398	Missense	distal	7	no	21.123	21.142	EPSD	ICGC;COSMIC	20.673	Up-regulation
TK_Src_SrcA_SRC_Y	P08238	HSP90AB1	P12931	SRC	Y56	R55L	55	Missense	proximal	-1	no	19.508	21.160	EPSD	ICGC	20.673	Gain
TK_Src_SrcA_SRC_Y	P08238	HSP90AB1	P12931	SRC	Y426	K428T	428	Missense	proximal	2	no	20.226	21.309	EPSD	ICGC	20.673	Gain
TK_Src_SrcA_SRC_Y	P08238	HSP90AB1	P12931	SRC	Y430	K428T	428	Missense	proximal	-2	no	21.849	21.781	EPSD	ICGC	20.673	Down-regulation
TK_Src_SrcA_SRC_Y	Q9NV92	NDFIP2	P12931	SRC	Y151	S153R	153	Missense	proximal	2	no	21.718	20.886	EPSD	ICGC;COSMIC	20.673	Down-regulation
TK_Src_SrcA_SRC_Y	Q9NV92	NDFIP2	P12931	SRC	Y167	V173M	173	Missense	distal	6	no	26.825	26.853	PhosphoSitePlus;EPSD	ICGC;COSMIC;CCLE	20.673	Up-regulation
TK_Src_SrcA_SRC_Y	Q9NV92	NDFIP2	P12931	SRC	Y167	D163Y	163	Missense	distal	-4	no	26.825	25.831	PhosphoSitePlus;EPSD	ICGC;COSMIC	20.673	Down-regulation
TK_Src_SrcA_SRC_Y	Q9NV92	NDFIP2	P12931	SRC	Y167	P172L	172	Missense	distal	5	no	26.825	26.839	PhosphoSitePlus;EPSD	ICGC	20.673	Up-regulation
TK_Src_SrcA_SRC_Y	Q9NV92	NDFIP2	P12931	SRC	Y167	G168C	168	Missense	proximal	1	no	26.825	24.528	PhosphoSitePlus;EPSD	ICGC;COSMIC	20.673	Down-regulation
TK_Src_SrcA_SRC_Y	Q9NV92	NDFIP2	P12931	SRC	Y167	T160A	160	Missense	distal	-7	no	26.825	26.405	PhosphoSitePlus;EPSD	ICGC;COSMIC	20.673	Down-regulation
TK_Src_SrcA_SRC_Y	Q9NV92	NDFIP2	P12931	SRC	Y171	V173M	173	Missense	proximal	2	no	20.974	20.708	EPSD;PhosphoSitePlus	ICGC;COSMIC;CCLE	20.673	Down-regulation
TK_Src_SrcA_SRC_Y	Q9NV92	NDFIP2	P12931	SRC	Y171	P172L	172	Missense	proximal	1	no	20.974	21.573	EPSD;PhosphoSitePlus	ICGC	20.673	Up-regulation
TK_Src_SrcA_SRC_Y	Q9NV92	NDFIP2	P12931	SRC	Y171	G168C	168	Missense	distal	-3	no	20.974	18.433	EPSD;PhosphoSitePlus	ICGC;COSMIC	20.673	Loss
TK_Src_SrcA_SRC_Y	P10398	ARAF	P12931	SRC	Y42	G38C	38	Missense	distal	-4	no	22.899	21.282	EPSD	ICGC;COSMIC	20.673	Down-regulation
TK_Src_SrcA_SRC_Y	P10398	ARAF	P12931	SRC	Y42	L49P	49	Missense	distal	7	no	22.899	22.906	EPSD	ICGC;COSMIC	20.673	Up-regulation
TK_Src_SrcA_SRC_Y	P10398	ARAF	P12931	SRC	Y155	R151C	151	Missense	distal	-4	no	20.789	19.190	EPSD	ICGC;COSMIC	20.673	Loss
TK_Src_SrcA_SRC_Y	P98175	RBM10	P12931	SRC	Y16	D11N	11	Missense	distal	-5	no	22.309	22.096	EPSD;PhosphoSitePlus	ICGC;COSMIC	20.673	Down-regulation
TK_Src_SrcA_SRC_Y	P98175	RBM10	P12931	SRC	Y16	D11Y	11	Missense	distal	-5	no	22.309	21.685	EPSD;PhosphoSitePlus	ICGC	20.673	Down-regulation
TK_Src_SrcA_SRC_Y	P98175	RBM10	P12931	SRC	Y16	Y16C	16	Missense	central	0	yes	22.309	0.000	EPSD;PhosphoSitePlus	ICGC;COSMIC	20.673	Loss
TK_Src_SrcA_SRC_Y	P98175	RBM10	P12931	SRC	Y36	D35N	35	Missense	proximal	-1	no	20.980	20.030	EPSD	ICGC;COSMIC	20.673	Loss
TK_Src_SrcA_SRC_Y	P98175	RBM10	P12931	SRC	Y36	R42S	42	Missense	distal	6	no	20.980	20.986	EPSD	ICGC;COSMIC	20.673	Up-regulation
TK_Src_SrcA_SRC_Y	P98175	RBM10	P12931	SRC	Y36	R37W	37	Missense	proximal	1	no	20.980	20.897	EPSD	ICGC	20.673	Down-regulation
TK_Src_SrcA_SRC_Y	P98175	RBM10	P12931	SRC	Y36	M39I	39	Missense	distal	3	no	20.980	21.286	EPSD	ICGC	20.673	Up-regulation
TK_Src_SrcA_SRC_Y	P98175	RBM10	P12931	SRC	Y36	R30C	30	Missense	distal	-6	no	20.980	20.584	EPSD	ICGC	20.673	Loss
TK_Src_SrcA_SRC_Y	P98175	RBM10	P12931	SRC	Y70	P74T	74	Missense	distal	4	no	22.513	22.528	EPSD	ICGC;COSMIC	20.673	Up-regulation
TK_Src_SrcA_SRC_Y	P98175	RBM10	P12931	SRC	Y70	E77K	77	Missense	distal	7	no	22.513	22.517	EPSD	ICGC;COSMIC	20.673	Up-regulation
TK_Src_SrcA_SRC_Y	P98175	RBM10	P12931	SRC	Y70	P74Q	74	Missense	distal	4	no	22.513	22.529	EPSD	ICGC;COSMIC	20.673	Up-regulation
TK_Src_SrcA_SRC_Y	P98175	RBM10	P12931	SRC	Y107	G112E	112	Missense	distal	5	no	21.824	21.667	EPSD	ICGC;COSMIC	20.673	Down-regulation
TK_Src_SrcA_SRC_Y	P98175	RBM10	P12931	SRC	Y107	G100S	100	Missense	distal	-7	no	21.824	22.198	EPSD	ICGC;COSMIC	20.673	Up-regulation
TK_Src_SrcA_SRC_Y	P51636	CAV2	P12931	SRC	Y27	Y27S	27	Missense	central	0	yes	23.474	0.000	EPSD	ICGC	20.673	Loss
TK_Src_SrcA_SRC_Y	P51636	CAV2	P12931	SRC	Y27	P30H	30	Missense	distal	3	no	23.474	22.878	EPSD	ICGC;COSMIC	20.673	Down-regulation
TK_Src_SrcA_SRC_Y	Q15642	TRIP10	P12931	SRC	Y190	N188K	188	Missense	proximal	-2	no	22.464	21.671	EPSD	ICGC;COSMIC	20.673	Down-regulation
TK_Src_SrcA_SRC_Y	Q15642	TRIP10	P12931	SRC	Y527	E532K	532	Missense	distal	5	no	23.906	23.938	EPSD	ICGC;COSMIC	20.673	Up-regulation
TK_Src_SrcA_SRC_Y	P52566	ARHGDIB	P12931	SRC	Y153	F155L	155	Missense	proximal	2	no	23.618	23.974	EPSD;PhosphoSitePlus	ICGC;COSMIC	20.673	Up-regulation
TK_Src_SrcA_SRC_Y	P52566	ARHGDIB	P12931	SRC	Y153	E151D	151	Missense	proximal	-2	no	23.618	23.330	EPSD;PhosphoSitePlus	ICGC	20.673	Down-regulation
TK_Src_SrcA_SRC_Y	P07900	HSP90AA1	P12931	SRC	Y160	A161P	161	Missense	proximal	1	no	24.090	22.144	EPSD	ICGC;COSMIC	20.673	Down-regulation
TK_Src_SrcA_SRC_Y	P07900	HSP90AA1	P12931	SRC	Y160	S165L	165	Missense	distal	5	no	24.090	24.282	EPSD	ICGC;COSMIC	20.673	Up-regulation
TK_Src_SrcA_SRC_Y	P07900	HSP90AA1	P12931	SRC	Y160	S164Y	164	Missense	distal	4	no	24.090	24.056	EPSD	ICGC	20.673	Down-regulation
TK_Src_SrcA_SRC_Y	P07900	HSP90AA1	P12931	SRC	Y197	L190P	190	Missense	distal	-7	no	20.768	20.883	PhosphoSitePlus	ICGC	20.673	Up-regulation
TK_Src_SrcA_SRC_Y	P07900	HSP90AA1	P12931	SRC	Y197	Y197C	197	Missense	central	0	yes	20.768	0.000	PhosphoSitePlus	ICGC;COSMIC	20.673	Loss
TK_Src_SrcA_SRC_Y	P07900	HSP90AA1	P12931	SRC	Y197	I203T	203	Missense	distal	6	no	20.768	20.738	PhosphoSitePlus	ICGC;COSMIC	20.673	Down-regulation
TK_Src_SrcA_SRC_Y	P07900	HSP90AA1	P12931	SRC	Y197	E199D	199	Missense	proximal	2	no	20.768	20.480	PhosphoSitePlus	ICGC;COSMIC	20.673	Loss
TK_Src_SrcA_SRC_Y	P07900	HSP90AA1	P12931	SRC	Y197	E196D	196	Missense	proximal	-1	no	20.768	19.858	PhosphoSitePlus	ICGC;COSMIC	20.673	Loss
TK_Src_SrcA_SRC_Y	P07900	HSP90AA1	P12931	SRC	Y309	G310R	310	Missense	proximal	1	no	24.311	23.317	EPSD	ICGC;COSMIC	20.673	Down-regulation
TK_Src_SrcA_SRC_Y	P07900	HSP90AA1	P12931	SRC	Y309	E307K	307	Missense	proximal	-2	no	24.311	22.951	EPSD	ICGC;COSMIC	20.673	Down-regulation
TK_Src_SrcA_SRC_Y	P07900	HSP90AA1	P12931	SRC	Y309	I304V	304	Missense	distal	-5	no	24.311	24.519	EPSD	ICGC;COSMIC	20.673	Up-regulation
TK_Src_SrcA_SRC_Y	P07900	HSP90AA1	P12931	SRC	Y309	F312L	312	Missense	distal	3	no	24.311	24.070	EPSD	ICGC;COSMIC	20.673	Down-regulation
TK_Src_SrcA_SRC_Y	P07900	HSP90AA1	P12931	SRC	Y313	G310R	310	Missense	distal	-3	no	22.272	21.380	EPSD	ICGC;COSMIC	20.673	Down-regulation
TK_Src_SrcA_SRC_Y	P07900	HSP90AA1	P12931	SRC	Y313	E307K	307	Missense	distal	-6	no	22.272	22.260	EPSD	ICGC;COSMIC	20.673	Down-regulation
TK_Src_SrcA_SRC_Y	P07900	HSP90AA1	P12931	SRC	Y313	F312L	312	Missense	proximal	-1	no	22.272	23.132	EPSD	ICGC;COSMIC	20.673	Up-regulation
TK_Src_SrcA_SRC_Y	P07900	HSP90AA1	P12931	SRC	Y438	Y434C	434	Missense	distal	-4	no	21.194	19.910	EPSD	ICGC;COSMIC	20.673	Loss
TK_Src_SrcA_SRC_Y	P07900	HSP90AA1	P12931	SRC	Y438	F441L	441	Missense	distal	3	no	21.194	20.953	EPSD	ICGC	20.673	Down-regulation
TK_Src_SrcA_SRC_Y	P07900	HSP90AA1	P12931	SRC	Y438	F437L	437	Missense	proximal	-1	no	21.194	22.053	EPSD	ICGC;COSMIC	20.673	Up-regulation
TK_Src_SrcA_SRC_Y	P07900	HSP90AA1	P12931	SRC	Y689	A685G	685	Missense	distal	-4	no	20.314	20.997	EPSD	ICGC;COSMIC	20.673	Gain
TK_Src_SrcA_SRC_Y	P49789	FHIT	P12931	SRC	Y114	N110I	110	Missense	distal	-4	no	24.910	23.369	PhosphoSitePlus	ICGC;COSMIC	20.673	Down-regulation
TK_Src_SrcA_SRC_Y	P49789	FHIT	P12931	SRC	Y114	E115D	115	Missense	proximal	1	no	24.910	24.304	PhosphoSitePlus	ICGC;COSMIC	20.673	Down-regulation
TK_Src_SrcA_SRC_Y	Q15417	CNN3	P12931	SRC	Y10	P8T	8	Missense	proximal	-2	no	20.934	19.910	PhosphoSitePlus	ICGC;COSMIC	20.673	Loss
TK_Src_SrcA_SRC_Y	Q15417	CNN3	P12931	SRC	Y300	D299Y	299	Missense	proximal	-1	no	20.411	21.574	EPSD	ICGC;COSMIC	20.673	Gain
TK_Src_SrcA_SRC_Y	Q01844	EWSR1	P12931	SRC	Y278	G284A	284	Missense	distal	6	no	21.957	21.942	PhosphoSitePlus	ICGC;COSMIC	20.673	Down-regulation
TK_Src_SrcA_SRC_Y	Q01844	EWSR1	P12931	SRC	Y364	A362S	362	Missense	proximal	-2	no	21.140	21.506	EPSD	ICGC;COSMIC	20.673	Up-regulation
TK_Src_SrcA_SRC_Y	Q01844	EWSR1	P12931	SRC	Y364	D370G	370	Missense	distal	6	no	21.140	21.181	EPSD	ICGC	20.673	Up-regulation
TK_Src_SrcA_SRC_Y	Q8IXJ6	SIRT2	P12931	SRC	Y104	K109Q	109	Missense	distal	5	no	21.286	21.254	PhosphoSitePlus	ICGC;COSMIC	20.673	Down-regulation
TK_Src_SrcA_SRC_Y	Q8IXJ6	SIRT2	P12931	SRC	Y104	G102S	102	Missense	proximal	-2	no	21.286	20.674	PhosphoSitePlus	ICGC;COSMIC	20.673	Down-regulation
TK_Src_SrcA_SRC_Y	Q8IXJ6	SIRT2	P12931	SRC	Y104	P99Q	99	Missense	distal	-5	no	21.286	21.146	PhosphoSitePlus	ICGC	20.673	Down-regulation
TK_Src_SrcA_SRC_Y	P56945	BCAR1	P12931	SRC	Y12	P19T	19	Missense	distal	7	no	20.696	20.646	EPSD	ICGC;COSMIC	20.673	Loss
TK_Src_SrcA_SRC_Y	P56945	BCAR1	P12931	SRC	Y115	P118T	118	Missense	distal	3	no	22.331	21.680	EPSD	ICGC	20.673	Down-regulation
TK_Src_SrcA_SRC_Y	P56945	BCAR1	P12931	SRC	Y128	P131T	131	Missense	distal	3	no	23.967	23.317	PhosphoSitePlus	ICGC;COSMIC	20.673	Down-regulation
TK_Src_SrcA_SRC_Y	P56945	BCAR1	P12931	SRC	Y224	P229H	229	Missense	distal	5	no	23.020	22.972	EPSD	ICGC;COSMIC	20.673	Down-regulation
TK_Src_SrcA_SRC_Y	P56945	BCAR1	P12931	SRC	Y234	P229H	229	Missense	distal	-5	no	23.780	24.008	EPSD	ICGC;COSMIC	20.673	Up-regulation
TK_Src_SrcA_SRC_Y	P56945	BCAR1	P12931	SRC	Y387	R391L	391	Missense	distal	4	no	22.339	22.373	EPSD	ICGC;COSMIC	20.673	Up-regulation
TK_Src_SrcA_SRC_Y	P56945	BCAR1	P12931	SRC	Y387	P381S	381	Missense	distal	-6	no	22.339	22.389	EPSD	ICGC;COSMIC	20.673	Up-regulation
TK_Src_SrcA_SRC_Y	P56945	BCAR1	P12931	SRC	Y387	R391W	391	Missense	distal	4	no	22.339	22.312	EPSD	ICGC;COSMIC	20.673	Down-regulation
TK_Src_SrcA_SRC_Y	Q05655	PRKCD	P12931	SRC	Y64	R67H	67	Missense	distal	3	no	21.321	22.511	EPSD	ICGC;COSMIC	20.673	Up-regulation
TK_Src_SrcA_SRC_Y	Q05655	PRKCD	P12931	SRC	Y64	T58M	58	Missense	distal	-6	no	21.321	20.833	EPSD	ICGC;COSMIC	20.673	Down-regulation
TK_Src_SrcA_SRC_Y	Q05655	PRKCD	P12931	SRC	Y313	T320N	320	Missense	distal	7	no	23.323	23.321	PhosphoSitePlus;EPSD	ICGC;COSMIC	20.673	Down-regulation
TK_Src_SrcA_SRC_Y	Q05655	PRKCD	P12931	SRC	Y567	V562A	562	Missense	distal	-5	no	21.050	21.049	EPSD	ICGC	20.673	Down-regulation
TK_Src_SrcA_SRC_Y	P46527	CDKN1B	P12931	SRC	Y74	V79L	79	Missense	distal	5	no	21.499	21.594	EPSD;PhosphoSitePlus	ICGC;COSMIC	20.673	Up-regulation
TK_Src_SrcA_SRC_Y	P46527	CDKN1B	P12931	SRC	Y74	E78K	78	Missense	distal	4	no	21.499	21.500	EPSD;PhosphoSitePlus	ICGC;COSMIC	20.673	Up-regulation
TK_Src_SrcA_SRC_Y	P46527	CDKN1B	P12931	SRC	Y88	Y89H	89	Missense	proximal	1	no	21.012	19.965	EPSD;PhosphoSitePlus	ICGC;COSMIC	20.673	Loss
TK_Src_SrcA_SRC_Y	P46527	CDKN1B	P12931	SRC	Y89	Y89H	89	Missense	central	0	yes	22.542	0.000	PhosphoSitePlus;EPSD	ICGC;COSMIC	20.673	Loss
TK_Src_SrcA_SRC_Y	Q96AC1	FERMT2	P12931	SRC	Y179	T172A	172	Missense	distal	-7	no	23.819	23.399	EPSD	ICGC;COSMIC	20.673	Down-regulation
TK_Src_SrcA_SRC_Y	Q96AE4	FUBP1	P12931	SRC	Y58	K64R	64	Missense	distal	6	no	21.958	21.926	EPSD;PhosphoSitePlus	ICGC;COSMIC	20.673	Down-regulation
TK_Src_SrcA_SRC_Y	Q96AE4	FUBP1	P12931	SRC	Y58	R65K	65	Missense	distal	7	no	21.958	21.932	EPSD;PhosphoSitePlus	ICGC;COSMIC;GDSC;CCLE	20.673	Down-regulation
TK_Src_SrcA_SRC_Y	Q96AE4	FUBP1	P12931	SRC	Y242	Q245H	245	Missense	distal	3	no	19.943	20.720	EPSD	ICGC;COSMIC	20.673	Gain
TK_Src_SrcA_SRC_Y	Q96AE4	FUBP1	P12931	SRC	Y590	A585D	585	Missense	distal	-5	no	21.333	21.516	EPSD	ICGC	20.673	Up-regulation
TK_Src_SrcA_SRC_Y	Q96AE4	FUBP1	P12931	SRC	Y590	V597F	597	Missense	distal	7	no	21.333	21.295	EPSD	ICGC;COSMIC	20.673	Down-regulation
TK_Src_SrcA_SRC_Y	Q96AE4	FUBP1	P12931	SRC	Y590	V597G	597	Missense	distal	7	no	21.333	21.299	EPSD	ICGC	20.673	Down-regulation
TK_Src_SrcA_SRC_Y	Q96AE4	FUBP1	P12931	SRC	Y611	S612N	612	Missense	proximal	1	no	21.502	20.603	EPSD	ICGC;COSMIC	20.673	Loss
TK_Src_SrcA_SRC_Y	Q96AE4	FUBP1	P12931	SRC	Y611	A616D	616	Missense	distal	5	no	21.502	21.389	EPSD	ICGC	20.673	Down-regulation
TK_Src_SrcA_SRC_Y	Q96AE4	FUBP1	P12931	SRC	Y611	Q608K	608	Missense	distal	-3	no	21.502	20.671	EPSD	ICGC	20.673	Loss
TK_Src_SrcA_SRC_Y	Q96AE4	FUBP1	P12931	SRC	Y611	P609Q	609	Missense	proximal	-2	no	21.502	20.716	EPSD	ICGC;COSMIC	20.673	Down-regulation
TK_Src_SrcA_SRC_Y	P55211	CASP9	P12931	SRC	Y251	A249D	249	Missense	proximal	-2	no	22.764	24.032	PhosphoSitePlus	ICGC	20.673	Up-regulation
TK_Src_SrcA_SRC_Y	O95297	MPZL1	P12931	SRC	Y263	S260Y	260	Missense	distal	-3	no	21.164	20.243	PhosphoSitePlus;EPSD	ICGC;COSMIC	20.673	Loss
TK_Src_SrcA_SRC_Y	O95297	MPZL1	P12931	SRC	Y263	V262L	262	Missense	proximal	-1	no	21.164	20.054	PhosphoSitePlus;EPSD	ICGC	20.673	Loss
TK_Src_SrcA_SRC_Y	Q9NPY3	CD93	P12931	SRC	Y628	A624V	624	Missense	distal	-4	no	21.340	21.206	EPSD;PhosphoSitePlus	ICGC;COSMIC	20.673	Down-regulation
TK_Src_SrcA_SRC_Y	Q9NPY3	CD93	P12931	SRC	Y628	P632Q	632	Missense	distal	4	no	21.340	21.356	EPSD;PhosphoSitePlus	ICGC;COSMIC	20.673	Up-regulation
TK_Src_SrcA_SRC_Y	Q9NPF5	DMAP1	P12931	SRC	Y58	L60F	60	Missense	proximal	2	no	21.313	20.957	EPSD	ICGC	20.673	Down-regulation
TK_Src_SrcA_SRC_Y	Q9NPF5	DMAP1	P12931	SRC	Y58	E56K	56	Missense	proximal	-2	no	21.313	19.954	EPSD	ICGC;COSMIC	20.673	Loss
TK_Src_SrcA_SRC_Y	O15056	SYNJ2	P12931	SRC	Y1136	H1133Y	1133	Missense	distal	-3	no	20.704	20.892	EPSD	ICGC;COSMIC	20.673	Up-regulation
TK_Src_SrcA_SRC_Y	O15056	SYNJ2	P12931	SRC	Y1136	R1143I	1143	Missense	distal	7	no	20.704	20.706	EPSD	ICGC;COSMIC	20.673	Up-regulation
TK_Src_SrcA_SRC_Y	O15056	SYNJ2	P12931	SRC	Y1411	A1404T	1404	Missense	distal	-7	no	20.502	20.922	EPSD	ICGC	20.673	Gain
TK_Src_SrcA_SRC_Y	Q99704	DOK1	P12931	SRC	Y315	D312G	312	Missense	distal	-3	no	21.446	20.797	EPSD	ICGC	20.673	Down-regulation
TK_Src_SrcA_SRC_Y	Q99704	DOK1	P12931	SRC	Y315	S321I	321	Missense	distal	6	no	21.446	21.467	EPSD	ICGC;COSMIC	20.673	Up-regulation
TK_Src_SrcA_SRC_Y	Q99704	DOK1	P12931	SRC	Y377	Y377H	377	Missense	central	0	yes	22.425	0.000	EPSD	ICGC	20.673	Loss
TK_Src_SrcA_SRC_Y	Q99704	DOK1	P12931	SRC	Y449	L448M	448	Missense	proximal	-1	no	23.467	22.971	EPSD	ICGC;COSMIC	20.673	Down-regulation
TK_Src_SrcA_SRC_Y	Q9UBS0	RPS6KB2	P12931	SRC	Y45	V48L	48	Missense	distal	3	no	21.312	21.339	PhosphoSitePlus	ICGC;COSMIC	20.673	Up-regulation
TK_Src_SrcA_SRC_Y	P51692	STAT5B	P12931	SRC	Y90	A91S	91	Missense	proximal	1	no	20.554	20.753	EPSD	ICGC;COSMIC	20.673	Gain
TK_Src_SrcA_SRC_Y	P51692	STAT5B	P12931	SRC	Y392	R389G	389	Missense	distal	-3	no	19.871	20.764	EPSD	ICGC	20.673	Gain
TK_Src_SrcA_SRC_Y	P51692	STAT5B	P12931	SRC	Y683	P687S	687	Missense	distal	4	no	20.658	20.680	EPSD	ICGC;COSMIC	20.673	Gain
TK_Src_SrcA_SRC_Y	P51692	STAT5B	P12931	SRC	Y699	A695S	695	Missense	distal	-4	no	20.320	20.715	PhosphoSitePlus	ICGC;COSMIC	20.673	Gain
TK_Src_SrcA_SRC_Y	P63010	AP2B1	P12931	SRC	Y136	P135L	135	Missense	proximal	-1	no	20.851	20.837	EPSD	ICGC	20.673	Down-regulation
TK_Src_SrcA_SRC_Y	P63010	AP2B1	P12931	SRC	Y333	K327N	327	Missense	distal	-6	no	21.042	20.942	EPSD	ICGC;COSMIC	20.673	Down-regulation
TK_Src_SrcA_SRC_Y	P63010	AP2B1	P12931	SRC	Y333	D330V	330	Missense	distal	-3	no	21.042	19.117	EPSD	ICGC	20.673	Loss
TK_Src_SrcA_SRC_Y	P63010	AP2B1	P12931	SRC	Y333	K327T	327	Missense	distal	-6	no	21.042	20.916	EPSD	ICGC;COSMIC	20.673	Down-regulation
TK_Src_SrcA_SRC_Y	P63010	AP2B1	P12931	SRC	Y737	T730S	730	Missense	distal	-7	no	20.908	20.812	PhosphoSitePlus	ICGC	20.673	Down-regulation
TK_Src_SrcA_SRC_Y	P63010	AP2B1	P12931	SRC	Y737	T730N	730	Missense	distal	-7	no	20.908	20.780	PhosphoSitePlus	ICGC	20.673	Down-regulation
TK_Src_SrcA_SRC_Y	P63010	AP2B1	P12931	SRC	Y874	N871S	871	Missense	distal	-3	no	22.092	22.132	EPSD	ICGC	20.673	Up-regulation
TK_Src_SrcA_SRC_Y	P63010	AP2B1	P12931	SRC	Y874	K867N	867	Missense	distal	-7	no	22.092	22.146	EPSD	ICGC	20.673	Up-regulation
TK_Src_SrcA_SRC_Y	P63010	AP2B1	P12931	SRC	Y874	T875A	875	Missense	proximal	1	no	22.092	22.547	EPSD	ICGC	20.673	Up-regulation
TK_Src_SrcA_SRC_Y	P63010	AP2B1	P12931	SRC	Y888	D885N	885	Missense	distal	-3	no	21.234	20.725	EPSD	ICGC	20.673	Down-regulation
TK_Src_SrcA_SRC_Y	P63000	RAC1	P12931	SRC	Y64	D63E	63	Missense	proximal	-1	no	21.521	22.430	PhosphoSitePlus	ICGC;COSMIC	20.673	Up-regulation
TK_Src_SrcA_SRC_Y	P63000	RAC1	P12931	SRC	Y64	D57N	57	Missense	distal	-7	no	21.521	21.440	PhosphoSitePlus	ICGC;COSMIC	20.673	Down-regulation
TK_Src_SrcA_SRC_Y	P63000	RAC1	P12931	SRC	Y64	E62K	62	Missense	proximal	-2	no	21.521	20.161	PhosphoSitePlus	ICGC;COSMIC	20.673	Loss
TK_Src_SrcA_SRC_Y	Q12913	PTPRJ	P12931	SRC	Y1077	V1074G	1074	Missense	distal	-3	no	20.016	21.292	EPSD	ICGC	20.673	Gain
TK_Src_SrcA_SRC_Y	Q12913	PTPRJ	P12931	SRC	Y1094	A1097S	1097	Missense	distal	3	no	21.844	21.800	EPSD	ICGC	20.673	Down-regulation
TK_Src_SrcA_SRC_Y	Q12913	PTPRJ	P12931	SRC	Y1094	Y1094C	1094	Missense	central	0	yes	21.844	0.000	EPSD	ICGC;COSMIC	20.673	Loss
TK_Src_SrcA_SRC_Y	Q12913	PTPRJ	P12931	SRC	Y1094	N1098K	1098	Missense	distal	4	no	21.844	21.800	EPSD	ICGC;COSMIC	20.673	Down-regulation
TK_Src_SrcA_SRC_Y	Q12913	PTPRJ	P12931	SRC	Y1311	T1318S	1318	Missense	distal	7	no	20.784	20.814	EPSD;PhosphoSitePlus	ICGC;COSMIC	20.673	Up-regulation
TK_Src_SrcA_SRC_Y	O15350	TP73	P12931	SRC	Y28	D30Y	30	Missense	proximal	2	no	21.706	21.726	PhosphoSitePlus	ICGC	20.673	Up-regulation
TK_Src_SrcA_SRC_Y	O15350	TP73	P12931	SRC	Y99	S104F	104	Missense	distal	5	no	20.647	20.896	EPSD	ICGC;COSMIC	20.673	Gain
TK_Src_SrcA_SRC_Y	Q96KG7	MEGF10	P12931	SRC	Y1016	S1022F	1022	Missense	distal	6	no	22.190	22.221	EPSD	ICGC	20.673	Up-regulation
TK_Src_SrcA_SRC_Y	Q96KG7	MEGF10	P12931	SRC	Y1016	L1010Q	1010	Missense	distal	-6	no	22.190	22.221	EPSD	ICGC;COSMIC	20.673	Up-regulation
TK_Src_SrcA_SRC_Y	Q96KG7	MEGF10	P12931	SRC	Y1030	N1028I	1028	Missense	proximal	-2	no	21.659	20.055	PhosphoSitePlus	ICGC	20.673	Loss
TK_Src_SrcA_SRC_Y	Q96KG7	MEGF10	P12931	SRC	Y1061	R1056Q	1056	Missense	distal	-5	no	22.793	22.634	EPSD	ICGC;COSMIC	20.673	Down-regulation
TK_Src_SrcA_SRC_Y	Q96KG7	MEGF10	P12931	SRC	Y1061	P1054L	1054	Missense	distal	-7	no	22.793	22.678	EPSD	ICGC;COSMIC	20.673	Down-regulation
TK_Src_SrcA_SRC_Y	Q96KG7	MEGF10	P12931	SRC	Y1075	R1072K	1072	Missense	distal	-3	no	24.403	24.188	EPSD	ICGC;COSMIC	20.673	Down-regulation
TK_Src_SrcA_SRC_Y	Q96KG7	MEGF10	P12931	SRC	Y1075	P1079F	1079	Missense	distal	4	no	24.403	24.414	EPSD	ICGC	20.673	Up-regulation
TK_Src_SrcA_SRC_Y	Q96KG7	MEGF10	P12931	SRC	Y1075	V1077A	1077	Missense	proximal	2	no	24.403	24.193	EPSD	ICGC	20.673	Down-regulation
TK_Src_SrcA_SRC_Y	Q9P219	CCDC88C	P12931	SRC	Y1272	H1276Y	1276	Missense	distal	4	no	21.980	21.959	EPSD	ICGC;COSMIC;CCLE	20.673	Down-regulation
TK_Src_SrcA_SRC_Y	P19404	NDUFV2	P12931	SRC	Y193	Y192H	192	Missense	proximal	-1	no	24.443	23.848	PhosphoSitePlus	ICGC;COSMIC	20.673	Down-regulation
TK_Src_SrcA_SRC_Y	P52789	HK2	P12931	SRC	Y112	D117Y	117	Missense	distal	5	no	21.159	21.732	EPSD	ICGC	20.673	Up-regulation
TK_Src_SrcA_SRC_Y	P14921	ETS1	P12931	SRC	Y283	P281Q	281	Missense	proximal	-2	no	20.953	20.167	PhosphoSitePlus	ICGC	20.673	Loss
TK_Src_SrcA_SRC_Y	P23743	DGKA	P12931	SRC	Y50	F56V	56	Missense	distal	6	no	21.272	21.255	EPSD	ICGC;COSMIC	20.673	Down-regulation
TK_Src_SrcA_SRC_Y	P23743	DGKA	P12931	SRC	Y50	E51D	51	Missense	proximal	1	no	21.272	20.666	EPSD	ICGC	20.673	Loss
TK_Src_SrcA_SRC_Y	P23743	DGKA	P12931	SRC	Y50	D46N	46	Missense	distal	-4	no	21.272	20.739	EPSD	ICGC;COSMIC	20.673	Down-regulation
TK_Src_SrcA_SRC_Y	P23743	DGKA	P12931	SRC	Y623	R616G	616	Missense	distal	-7	no	23.173	22.552	EPSD	ICGC;COSMIC	20.673	Down-regulation
TK_Src_SrcA_SRC_Y	Q00987	MDM2	P12931	SRC	Y281	E285D	285	Missense	distal	4	no	22.943	22.971	PhosphoSitePlus;EPSD	ICGC;COSMIC	20.673	Up-regulation
TK_Src_SrcA_SRC_Y	Q00987	MDM2	P12931	SRC	Y394	S400C	400	Missense	distal	6	no	25.302	25.377	EPSD	ICGC;COSMIC	20.673	Up-regulation
TK_Src_SrcA_SRC_Y	Q00987	MDM2	P12931	SRC	Y394	E390Q	390	Missense	distal	-4	no	25.302	24.472	EPSD	ICGC;COSMIC	20.673	Down-regulation
TK_Src_SrcA_SRC_Y	P36544	CHRNA7	P12931	SRC	Y386	N383K	383	Missense	distal	-3	no	21.135	19.886	PhosphoSitePlus;EPSD	ICGC;COSMIC	20.673	Loss
TK_Src_SrcA_SRC_Y	P03372	ESR1	P12931	SRC	Y52	A50S	50	Missense	proximal	-2	no	20.566	20.932	EPSD	ICGC	20.673	Gain
TK_Src_SrcA_SRC_Y	P03372	ESR1	P12931	SRC	Y537	Y537C	537	Missense	central	0	yes	21.208	0.000	PhosphoSitePlus	ICGC;COSMIC	20.673	Loss
TK_Src_SrcA_SRC_Y	P03372	ESR1	P12931	SRC	Y537	K531M	531	Missense	distal	-6	no	21.208	20.593	PhosphoSitePlus	ICGC;COSMIC	20.673	Loss
TK_Src_SrcA_SRC_Y	P03372	ESR1	P12931	SRC	Y537	P535L	535	Missense	proximal	-2	no	21.208	19.677	PhosphoSitePlus	ICGC;COSMIC	20.673	Loss
TK_Src_SrcA_SRC_Y	P03372	ESR1	P12931	SRC	Y537	K531N	531	Missense	distal	-6	no	21.208	21.107	PhosphoSitePlus	ICGC	20.673	Down-regulation
TK_Src_SrcA_SRC_Y	P03372	ESR1	P12931	SRC	Y537	C530F	530	Missense	distal	-7	no	21.208	21.768	PhosphoSitePlus	ICGC	20.673	Up-regulation
TK_Src_SrcA_SRC_Y	P18827	SDC1	P12931	SRC	Y299	G296S	296	Missense	distal	-3	no	20.945	21.126	EPSD	ICGC	20.673	Up-regulation
TK_Src_SrcA_SRC_Y	P18827	SDC1	P12931	SRC	Y299	Y299C	299	Missense	central	0	yes	20.945	0.000	EPSD	ICGC	20.673	Loss
TK_Src_SrcA_SRC_Y	Q9UKW4	VAV3	P12931	SRC	Y141	P145A	145	Missense	distal	4	no	24.102	24.121	EPSD	ICGC;COSMIC	20.673	Up-regulation
TK_Src_SrcA_SRC_Y	Q9UKW4	VAV3	P12931	SRC	Y173	L176I	176	Missense	distal	3	no	24.937	24.850	PhosphoSitePlus	ICGC	20.673	Down-regulation
TK_Src_SrcA_SRC_Y	Q9UKW4	VAV3	P12931	SRC	Y207	S213L	213	Missense	distal	6	no	21.098	21.130	EPSD	ICGC	20.673	Up-regulation
TK_Src_SrcA_SRC_Y	Q9UKW4	VAV3	P12931	SRC	Y265	K259E	259	Missense	distal	-6	no	23.288	23.300	EPSD	ICGC;COSMIC	20.673	Up-regulation
TK_Src_SrcA_SRC_Y	Q9UKW4	VAV3	P12931	SRC	Y706	K701E	701	Missense	distal	-5	no	21.623	22.199	EPSD	ICGC	20.673	Up-regulation
TK_Src_SrcA_SRC_Y	P61586	RHOA	P12931	SRC	Y66	A61V	61	Missense	distal	-5	no	20.795	20.796	PhosphoSitePlus;EPSD	ICGC;COSMIC;GDSC;CCLE	20.673	Up-regulation
TK_Src_SrcA_SRC_Y	P61586	RHOA	P12931	SRC	Y66	L69R	69	Missense	distal	3	no	20.795	19.107	PhosphoSitePlus;EPSD	ICGC;COSMIC	20.673	Loss
TK_Src_SrcA_SRC_Y	P61586	RHOA	P12931	SRC	Y66	E64D	64	Missense	proximal	-2	no	20.795	20.508	PhosphoSitePlus;EPSD	ICGC;COSMIC	20.673	Loss
TK_Src_SrcA_SRC_Y	P07949	RET	P12931	SRC	Y687	S686I	686	Missense	proximal	-1	no	20.253	21.326	EPSD	ICGC	20.673	Gain
TK_Src_SrcA_SRC_Y	P07949	RET	P12931	SRC	Y687	A680T	680	Missense	distal	-7	no	20.253	20.673	EPSD	ICGC;COSMIC;GDSC;CCLE	20.673	Gain
TK_Src_SrcA_SRC_Y	P07949	RET	P12931	SRC	Y900	G894V	894	Missense	distal	-6	no	22.850	22.743	EPSD	ICGC	20.673	Down-regulation
TK_Src_SrcA_SRC_Y	P07949	RET	P12931	SRC	Y900	S904Y	904	Missense	distal	4	no	22.850	22.815	EPSD	ICGC;COSMIC	20.673	Down-regulation
TK_Src_SrcA_SRC_Y	P07949	RET	P12931	SRC	Y900	K907N	907	Missense	distal	7	no	22.850	22.805	EPSD	ICGC;COSMIC	20.673	Down-regulation
TK_Src_SrcA_SRC_Y	P07949	RET	P12931	SRC	Y905	S904Y	904	Missense	proximal	-1	no	24.148	25.324	PhosphoSitePlus	ICGC;COSMIC	20.673	Up-regulation
TK_Src_SrcA_SRC_Y	P07949	RET	P12931	SRC	Y905	K907N	907	Missense	proximal	2	no	24.148	25.243	PhosphoSitePlus	ICGC;COSMIC	20.673	Up-regulation
TK_Src_SrcA_SRC_Y	P07949	RET	P12931	SRC	Y1029	G1032S	1032	Missense	distal	3	no	22.382	22.145	EPSD	ICGC;COSMIC	20.673	Down-regulation
TK_Src_SrcA_SRC_Y	P07949	RET	P12931	SRC	Y1062	W1056L	1056	Missense	distal	-6	no	21.549	21.888	EPSD	ICGC	20.673	Up-regulation
TK_Src_SrcA_SRC_Y	P07949	RET	P12931	SRC	Y1096	S1102P	1102	Missense	distal	6	no	22.266	22.282	EPSD	ICGC	20.673	Up-regulation
TK_Src_SrcA_SRC_Y	P07949	RET	P12931	SRC	Y1096	A1097S	1097	Missense	proximal	1	no	22.266	22.466	EPSD	ICGC;COSMIC	20.673	Up-regulation
TK_Src_SrcA_SRC_Y	P07949	RET	P12931	SRC	Y1096	W1099C	1099	Missense	distal	3	no	22.266	22.575	EPSD	ICGC	20.673	Up-regulation
TK_Src_SrcA_SRC_Y	Q92529	SHC3	P12931	SRC	Y341	N343K	343	Missense	proximal	2	no	22.240	21.145	EPSD	ICGC	20.673	Down-regulation
TK_Src_SrcA_SRC_Y	Q92529	SHC3	P12931	SRC	Y341	S344R	344	Missense	distal	3	no	22.240	21.193	EPSD	ICGC	20.673	Down-regulation
TK_Src_SrcA_SRC_Y	Q92529	SHC3	P12931	SRC	Y341	H339L	339	Missense	proximal	-2	no	22.240	21.375	EPSD	ICGC;COSMIC	20.673	Down-regulation
TK_Src_SrcA_SRC_Y	Q92529	SHC3	P12931	SRC	Y342	N343K	343	Missense	proximal	1	no	22.964	22.567	EPSD	ICGC	20.673	Down-regulation
TK_Src_SrcA_SRC_Y	Q92529	SHC3	P12931	SRC	Y342	S344R	344	Missense	proximal	2	no	22.964	22.133	EPSD	ICGC	20.673	Down-regulation
TK_Src_SrcA_SRC_Y	Q92529	SHC3	P12931	SRC	Y342	H339L	339	Missense	distal	-3	no	22.964	21.805	EPSD	ICGC;COSMIC	20.673	Down-regulation
TK_Src_SrcA_SRC_Y	Q92529	SHC3	P12931	SRC	Y379	G374R	374	Missense	distal	-5	no	22.159	22.144	EPSD	ICGC;COSMIC	20.673	Down-regulation
TK_Src_SrcA_SRC_Y	Q92529	SHC3	P12931	SRC	Y379	Q381K	381	Missense	proximal	2	no	22.159	21.299	EPSD	ICGC	20.673	Down-regulation
TK_Src_SrcA_SRC_Y	Q92529	SHC3	P12931	SRC	Y379	G374E	374	Missense	distal	-5	no	22.159	22.412	EPSD	ICGC;COSMIC	20.673	Up-regulation
TK_Src_SrcA_SRC_Y	Q92529	SHC3	P12931	SRC	Y380	G374R	374	Missense	distal	-6	no	20.950	20.952	EPSD	ICGC;COSMIC	20.673	Up-regulation
TK_Src_SrcA_SRC_Y	Q92529	SHC3	P12931	SRC	Y380	Q381K	381	Missense	proximal	1	no	20.950	19.540	EPSD	ICGC	20.673	Loss
TK_Src_SrcA_SRC_Y	Q92529	SHC3	P12931	SRC	Y380	G374E	374	Missense	distal	-6	no	20.950	21.179	EPSD	ICGC;COSMIC	20.673	Up-regulation
TK_Src_SrcA_SRC_Y	Q92529	SHC3	P12931	SRC	Y380	D387Y	387	Missense	distal	7	no	20.950	20.967	EPSD	ICGC	20.673	Up-regulation
TK_Src_SrcA_SRC_Y	Q92529	SHC3	P12931	SRC	Y406	S407T	407	Missense	proximal	1	no	25.471	24.817	EPSD	ICGC;COSMIC	20.673	Down-regulation
TK_Src_SrcA_SRC_Y	Q92529	SHC3	P12931	SRC	Y406	P409Q	409	Missense	distal	3	no	25.471	24.097	EPSD	ICGC	20.673	Down-regulation
TK_Src_SrcA_SRC_Y	Q92529	SHC3	P12931	SRC	Y406	T408K	408	Missense	proximal	2	no	25.471	24.387	EPSD	ICGC	20.673	Down-regulation
TK_Src_SrcA_SRC_Y	Q92529	SHC3	P12931	SRC	Y424	P431L	431	Missense	distal	7	no	23.493	23.487	EPSD	ICGC;COSMIC	20.673	Down-regulation
TK_Src_SrcA_SRC_Y	Q92529	SHC3	P12931	SRC	Y424	Q428K	428	Missense	distal	4	no	23.493	23.486	EPSD	ICGC	20.673	Down-regulation
TK_Src_SrcA_SRC_Y	Q92529	SHC3	P12931	SRC	Y424	T418K	418	Missense	distal	-6	no	23.493	23.619	EPSD	ICGC	20.673	Up-regulation
TK_Src_SrcA_SRC_Y	Q92529	SHC3	P12931	SRC	Y424	V425I	425	Missense	proximal	1	no	23.493	22.833	EPSD	ICGC;COSMIC	20.673	Down-regulation
TK_Src_SrcA_SRC_Y	P23528	CFL1	P12931	SRC	Y140	E134V	134	Missense	distal	-6	no	22.300	21.963	EPSD	ICGC;COSMIC	20.673	Down-regulation
TK_Src_SrcA_SRC_Y	P50402	EMD	P12931	SRC	Y74	K78M	78	Missense	distal	4	no	24.147	24.094	PhosphoSitePlus;EPSD	ICGC;COSMIC	20.673	Down-regulation
TK_Src_SrcA_SRC_Y	P50402	EMD	P12931	SRC	Y161	M154I	154	Missense	distal	-7	no	23.589	23.874	EPSD	ICGC;COSMIC	20.673	Up-regulation
TK_Src_SrcA_SRC_Y	P50402	EMD	P12931	SRC	Y161	G156C	156	Missense	distal	-5	no	23.589	22.854	EPSD	ICGC;COSMIC	20.673	Down-regulation
TK_Src_SrcA_SRC_Y	P05023	ATP1A1	P12931	SRC	Y10	K3R	3	Missense	distal	-7	no	21.659	21.993	EPSD	ICGC;COSMIC	20.673	Up-regulation
TK_Src_SrcA_SRC_Y	P05023	ATP1A1	P12931	SRC	Y902	D897Y	897	Missense	distal	-5	no	20.791	20.167	EPSD	ICGC;COSMIC	20.673	Loss
TK_Src_SrcA_SRC_Y	Q86UR1	NOXA1	P12931	SRC	Y110	D109Y	109	Missense	proximal	-1	no	19.600	20.763	PhosphoSitePlus	ICGC	20.673	Gain
TK_Src_SrcA_SRC_Y	Q9H2X6	HIPK2	P12931	SRC	Y44	H47N	47	Missense	distal	3	no	20.406	21.203	EPSD	ICGC;COSMIC	20.673	Gain
TK_Src_SrcA_SRC_Y	Q9Y446	PKP3	P12931	SRC	Y195	R194H	194	Missense	proximal	-1	no	18.792	20.687	PhosphoSitePlus	ICGC	20.673	Gain
TK_Src_SrcA_SRC_Y	Q9Y446	PKP3	P12931	SRC	Y210	A206T	206	Missense	distal	-4	no	20.472	20.747	EPSD	ICGC	20.673	Gain
TK_Src_SrcA_SRC_Y	Q9Y446	PKP3	P12931	SRC	Y303	H298Y	298	Missense	distal	-5	no	20.900	20.235	EPSD	ICGC;COSMIC	20.673	Loss
TK_Src_SrcA_SRC_Y	Q9Y446	PKP3	P12931	SRC	Y539	A546T	546	Missense	distal	7	no	20.863	20.843	EPSD	ICGC;COSMIC	20.673	Down-regulation
TK_Src_SrcA_SRC_Y	Q9Y446	PKP3	P12931	SRC	Y539	E541D	541	Missense	proximal	2	no	20.863	20.575	EPSD	ICGC;COSMIC	20.673	Loss
TK_Src_SrcA_SRC_Y	Q9Y446	PKP3	P12931	SRC	Y539	Y539N	539	Missense	central	0	yes	20.863	0.000	EPSD	ICGC	20.673	Loss
TK_Src_SrcA_SRC_Y	P31040	SDHA	P12931	SRC	Y604	E603K	603	Missense	proximal	-1	no	21.211	19.303	EPSD	ICGC;COSMIC	20.673	Loss
TK_Src_SrcA_SRC_Y	P31040	SDHA	P12931	SRC	Y606	E603K	603	Missense	distal	-3	no	20.944	19.233	EPSD	ICGC;COSMIC	20.673	Loss
TK_Src_SrcA_SRC_Y	O14746	TERT	P12931	SRC	Y949	S947F	947	Missense	proximal	-2	no	21.333	20.353	EPSD	ICGC;COSMIC	20.673	Loss
TK_Src_SrcA_SRC_Y	O43597	SPRY2	P12931	SRC	Y55	P59L	59	Missense	distal	4	no	22.341	22.369	PhosphoSitePlus	ICGC	20.673	Up-regulation
TK_Src_SrcA_SRC_Y	O43597	SPRY2	P12931	SRC	Y55	V62I	62	Missense	distal	7	no	22.341	22.315	PhosphoSitePlus	ICGC;COSMIC	20.673	Down-regulation
TK_Src_SrcA_SRC_Y	Q15746	MYLK	P12931	SRC	Y231	D227E	227	Missense	distal	-4	no	22.717	22.491	EPSD	ICGC	20.673	Down-regulation
TK_Src_SrcA_SRC_Y	Q15746	MYLK	P12931	SRC	Y464	Y464F	464	Missense	central	0	yes	22.458	0.000	PhosphoSitePlus;EPSD	ICGC;COSMIC	20.673	Loss
TK_Src_SrcA_SRC_Y	Q15746	MYLK	P12931	SRC	Y846	R845C	845	Missense	proximal	-1	no	21.336	22.758	EPSD	ICGC;COSMIC	20.673	Up-regulation
TK_Src_SrcA_SRC_Y	Q15746	MYLK	P12931	SRC	Y846	G841C	841	Missense	distal	-5	no	21.336	20.601	EPSD	ICGC;COSMIC	20.673	Loss
TK_Src_SrcA_SRC_Y	P37840	SNCA	P12931	SRC	Y125	P120T	120	Missense	distal	-5	no	23.320	23.113	PhosphoSitePlus	ICGC	20.673	Down-regulation
TK_Src_SrcA_SRC_Y	Q14289	PTK2B	P12931	SRC	Y402	D407N	407	Missense	distal	5	no	22.034	22.192	PhosphoSitePlus	ICGC;COSMIC	20.673	Up-regulation
TK_Src_SrcA_SRC_Y	Q14289	PTK2B	P12931	SRC	Y402	T409A	409	Missense	distal	7	no	22.034	22.054	PhosphoSitePlus	ICGC	20.673	Up-regulation
TK_Src_SrcA_SRC_Y	Q14289	PTK2B	P12931	SRC	Y402	E404D	404	Missense	proximal	2	no	22.034	21.747	PhosphoSitePlus	ICGC	20.673	Down-regulation
TK_Src_SrcA_SRC_Y	Q14289	PTK2B	P12931	SRC	Y440	G442A	442	Missense	proximal	2	no	22.476	23.251	EPSD	ICGC;COSMIC	20.673	Up-regulation
TK_Src_SrcA_SRC_Y	Q14289	PTK2B	P12931	SRC	Y440	E433Q	433	Missense	distal	-7	no	22.476	22.422	EPSD	ICGC;COSMIC	20.673	Down-regulation
TK_Src_SrcA_SRC_Y	Q14289	PTK2B	P12931	SRC	Y579	R572L	572	Missense	distal	-7	no	26.652	26.169	EPSD	ICGC	20.673	Down-regulation
TK_Src_SrcA_SRC_Y	Q14289	PTK2B	P12931	SRC	Y579	R572W	572	Missense	distal	-7	no	26.652	26.179	EPSD	ICGC;GDSC;CCLE	20.673	Down-regulation
TK_Src_SrcA_SRC_Y	Q14289	PTK2B	P12931	SRC	Y579	I574F	574	Missense	distal	-5	no	26.652	26.635	EPSD	ICGC;COSMIC	20.673	Down-regulation
TK_Src_SrcA_SRC_Y	Q14289	PTK2B	P12931	SRC	Y580	I574F	574	Missense	distal	-6	no	23.910	23.796	EPSD	ICGC;COSMIC	20.673	Down-regulation
TK_Src_SrcA_SRC_Y	Q14289	PTK2B	P12931	SRC	Y849	F852L	852	Missense	distal	3	no	21.052	20.812	EPSD	ICGC;COSMIC	20.673	Down-regulation
TK_Src_SrcA_SRC_Y	Q14289	PTK2B	P12931	SRC	Y849	E851K	851	Missense	proximal	2	no	21.052	19.883	EPSD	ICGC;COSMIC	20.673	Loss
TK_Src_SrcA_SRC_Y	Q14289	PTK2B	P12931	SRC	Y881	N883S	883	Missense	proximal	2	no	22.556	22.803	EPSD	ICGC;COSMIC;GDSC;CCLE	20.673	Up-regulation
TK_Src_SrcA_SRC_Y	P18433	PTPRA	P12931	SRC	Y271	R270Q	270	Missense	proximal	-1	no	19.146	20.979	EPSD	ICGC;COSMIC	20.673	Gain
TK_Src_SrcA_SRC_Y	P10275	AR	P12931	SRC	Y269	M268I	268	Missense	proximal	-1	no	21.045	22.277	EPSD	ICGC	20.673	Up-regulation
TK_Src_SrcA_SRC_Y	P10275	AR	P12931	SRC	Y269	P271T	271	Missense	proximal	2	no	21.045	21.394	EPSD	ICGC;COSMIC	20.673	Up-regulation
TK_Src_SrcA_SRC_Y	P10275	AR	P12931	SRC	Y269	L273F	273	Missense	distal	4	no	21.045	21.027	EPSD	ICGC;COSMIC	20.673	Down-regulation
TK_Src_SrcA_SRC_Y	P10275	AR	P12931	SRC	Y309	T303S	303	Missense	distal	-6	no	23.332	23.384	EPSD	ICGC;COSMIC	20.673	Up-regulation
TK_Src_SrcA_SRC_Y	P10275	AR	P12931	SRC	Y309	G314R	314	Missense	distal	5	no	23.332	23.151	EPSD	ICGC	20.673	Down-regulation
TK_Src_SrcA_SRC_Y	P10275	AR	P12931	SRC	Y364	A358V	358	Missense	distal	-6	no	21.254	21.094	EPSD	ICGC;COSMIC	20.673	Down-regulation
TK_Src_SrcA_SRC_Y	P10275	AR	P12931	SRC	Y364	Q360R	360	Missense	distal	-4	no	21.254	21.633	EPSD	ICGC;COSMIC	20.673	Up-regulation
TK_Src_SrcA_SRC_Y	P10275	AR	P12931	SRC	Y364	A370P	370	Missense	distal	6	no	21.254	21.266	EPSD	ICGC;COSMIC	20.673	Up-regulation
TK_Src_SrcA_SRC_Y	P10275	AR	P12931	SRC	Y364	D363N	363	Missense	proximal	-1	no	21.254	20.304	EPSD	ICGC	20.673	Loss
TK_Src_SrcA_SRC_Y	P10275	AR	P12931	SRC	Y365	Q360R	360	Missense	distal	-5	no	20.577	20.736	EPSD	ICGC;COSMIC	20.673	Gain
TK_Src_SrcA_SRC_Y	P10275	AR	P12931	SRC	Y365	A370P	370	Missense	distal	5	no	20.577	20.799	EPSD	ICGC;COSMIC	20.673	Gain
TK_Src_SrcA_SRC_Y	P10275	AR	P12931	SRC	Y535	M538I	538	Missense	distal	3	no	22.172	22.478	PhosphoSitePlus	ICGC	20.673	Up-regulation
TK_Src_SrcA_SRC_Y	P10275	AR	P12931	SRC	Y535	G533R	533	Missense	proximal	-2	no	22.172	20.814	PhosphoSitePlus	ICGC;COSMIC	20.673	Down-regulation
TK_Src_SrcA_SRC_Y	O14976	GAK	P12931	SRC	Y204	D203E	203	Missense	proximal	-1	no	20.178	21.087	EPSD	ICGC;COSMIC	20.673	Gain
TK_Src_SrcA_SRC_Y	O14976	GAK	P12931	SRC	Y285	D282N	282	Missense	distal	-3	no	22.876	22.368	EPSD	ICGC;COSMIC	20.673	Down-regulation
TK_Src_SrcA_SRC_Y	O14976	GAK	P12931	SRC	Y285	P280Q	280	Missense	distal	-5	no	22.876	22.735	EPSD	ICGC;COSMIC	20.673	Down-regulation
TK_Src_SrcA_SRC_Y	O14976	GAK	P12931	SRC	Y371	A365E	365	Missense	distal	-6	no	22.598	22.774	EPSD	ICGC;COSMIC	20.673	Up-regulation
TK_Src_SrcA_SRC_Y	O14976	GAK	P12931	SRC	Y371	A365V	365	Missense	distal	-6	no	22.598	22.438	EPSD	ICGC;COSMIC	20.673	Down-regulation
TK_Src_SrcA_SRC_Y	O14976	GAK	P12931	SRC	Y764	P771R	771	Missense	distal	7	no	21.459	21.477	EPSD	ICGC;COSMIC	20.673	Up-regulation
TK_Src_SrcA_SRC_Y	O14976	GAK	P12931	SRC	Y764	T761M	761	Missense	distal	-3	no	21.459	20.230	EPSD	ICGC;COSMIC	20.673	Loss
TK_Src_SrcA_SRC_Y	O14976	GAK	P12931	SRC	Y764	G769E	769	Missense	distal	5	no	21.459	21.302	EPSD	ICGC	20.673	Down-regulation
TK_Src_SrcA_SRC_Y	P02786	TFRC	P12931	SRC	Y402	A407T	407	Missense	distal	5	no	22.148	22.363	EPSD	ICGC	20.673	Up-regulation
TK_Src_SrcA_SRC_Y	P02786	TFRC	P12931	SRC	Y402	P399A	399	Missense	distal	-3	no	22.148	22.360	EPSD	ICGC	20.673	Up-regulation
TK_Src_SrcA_SRC_Y	P02786	TFRC	P12931	SRC	Y402	R409I	409	Missense	distal	7	no	22.148	22.150	EPSD	ICGC;COSMIC	20.673	Up-regulation
TK_Src_SrcA_SRC_Y	P02786	TFRC	P12931	SRC	Y402	P399Q	399	Missense	distal	-3	no	22.148	22.808	EPSD	ICGC;COSMIC	20.673	Up-regulation
TK_Src_SrcA_SRC_Y	P02786	TFRC	P12931	SRC	Y402	E398K	398	Missense	distal	-4	no	22.148	20.978	EPSD	ICGC;COSMIC;CCLE	20.673	Down-regulation
TK_Src_SrcA_SRC_Y	O60331	PIP5K1C	P12931	SRC	Y649	W647L	647	Missense	proximal	-2	no	21.315	22.266	PhosphoSitePlus	ICGC;COSMIC	20.673	Up-regulation
TK_Src_SrcA_SRC_Y	O60331	PIP5K1C	P12931	SRC	Y649	R645M	645	Missense	distal	-4	no	21.315	20.091	PhosphoSitePlus	ICGC;COSMIC	20.673	Loss
TK_Src_SrcA_SRC_Y	O60331	PIP5K1C	P12931	SRC	Y649	R645G	645	Missense	distal	-4	no	21.315	21.333	PhosphoSitePlus	ICGC;COSMIC;CCLE	20.673	Up-regulation
TK_Src_SrcA_SRC_Y	Q92558	WASF1	P12931	SRC	Y125	T124M	124	Missense	proximal	-1	no	20.803	20.550	PhosphoSitePlus	ICGC;COSMIC;GDSC;CCLE	20.673	Loss
TK_Src_SrcA_SRC_Y	A1X283	SH3PXD2B	P12931	SRC	Y42	Y45C	45	Missense	distal	3	no	23.015	21.940	EPSD	ICGC	20.673	Down-regulation
TK_Src_SrcA_SRC_Y	A1X283	SH3PXD2B	P12931	SRC	Y226	P231L	231	Missense	distal	5	no	22.598	22.613	EPSD	ICGC	20.673	Up-regulation
TK_Src_SrcA_SRC_Y	A1X283	SH3PXD2B	P12931	SRC	Y226	P231Q	231	Missense	distal	5	no	22.598	22.470	EPSD	ICGC	20.673	Down-regulation
TK_Src_SrcA_SRC_Y	A1X283	SH3PXD2B	P12931	SRC	Y226	E222D	222	Missense	distal	-4	no	22.598	22.824	EPSD	ICGC;COSMIC	20.673	Up-regulation
TK_Src_SrcA_SRC_Y	A1X283	SH3PXD2B	P12931	SRC	Y230	P231Q	231	Missense	proximal	1	no	19.054	21.313	EPSD	ICGC	20.673	Gain
TK_Src_SrcA_SRC_Y	A1X283	SH3PXD2B	P12931	SRC	Y373	I376F	376	Missense	distal	3	no	22.361	22.688	EPSD	ICGC;COSMIC	20.673	Up-regulation
TK_Src_SrcA_SRC_Y	A1X283	SH3PXD2B	P12931	SRC	Y373	A377S	377	Missense	distal	4	no	22.361	22.362	EPSD	ICGC;COSMIC	20.673	Up-regulation
TK_Src_SrcA_SRC_Y	A1X283	SH3PXD2B	P12931	SRC	Y374	I376F	376	Missense	proximal	2	no	23.334	23.250	EPSD	ICGC;COSMIC	20.673	Down-regulation
TK_Src_SrcA_SRC_Y	A1X283	SH3PXD2B	P12931	SRC	Y374	A377S	377	Missense	distal	3	no	23.334	23.290	EPSD	ICGC;COSMIC	20.673	Down-regulation
TK_Src_SrcA_SRC_Y	A1X283	SH3PXD2B	P12931	SRC	Y855	A857D	857	Missense	proximal	2	no	21.160	21.051	EPSD	ICGC	20.673	Down-regulation
TK_Src_SrcA_SRC_Y	A1X283	SH3PXD2B	P12931	SRC	Y855	Y855C	855	Missense	central	0	yes	21.160	0.000	EPSD	ICGC;COSMIC	20.673	Loss
TK_Src_SrcA_SRC_Y	P06493	CDK1	P12931	SRC	Y15	T14A	14	Missense	proximal	-1	no	24.693	24.710	PhosphoSitePlus	ICGC;COSMIC	20.673	Up-regulation
TK_Src_SrcA_SRC_Y	P06493	CDK1	P12931	SRC	Y181	R180C	180	Missense	proximal	-1	no	20.616	22.037	EPSD	ICGC	20.673	Gain
TK_Src_SrcA_SRC_Y	P22681	CBL	P12931	SRC	Y141	G136V	136	Missense	distal	-5	no	21.202	21.173	EPSD	ICGC	20.673	Down-regulation
TK_Src_SrcA_SRC_Y	P22681	CBL	P12931	SRC	Y368	Y371H	371	Missense	distal	3	no	22.291	22.194	EPSD	ICGC;COSMIC	20.673	Down-regulation
TK_Src_SrcA_SRC_Y	P22681	CBL	P12931	SRC	Y368	E366K	366	Missense	proximal	-2	no	22.291	20.932	EPSD	ICGC;COSMIC	20.673	Down-regulation
TK_Src_SrcA_SRC_Y	P22681	CBL	P12931	SRC	Y368	Y368C	368	Missense	central	0	yes	22.291	0.000	EPSD	ICGC;COSMIC	20.673	Loss
TK_Src_SrcA_SRC_Y	P22681	CBL	P12931	SRC	Y371	Y371H	371	Missense	central	0	yes	20.828	0.000	EPSD	ICGC;COSMIC	20.673	Loss
TK_Src_SrcA_SRC_Y	P22681	CBL	P12931	SRC	Y371	E366K	366	Missense	distal	-5	no	20.828	20.251	EPSD	ICGC;COSMIC	20.673	Loss
TK_Src_SrcA_SRC_Y	P22681	CBL	P12931	SRC	Y371	Y368C	368	Missense	distal	-3	no	20.828	19.027	EPSD	ICGC;COSMIC	20.673	Loss
TK_Src_SrcA_SRC_Y	P22681	CBL	P12931	SRC	Y455	D459V	459	Missense	distal	4	no	20.772	20.727	EPSD	ICGC;COSMIC	20.673	Down-regulation
TK_Src_SrcA_SRC_Y	P22681	CBL	P12931	SRC	Y700	M701L	701	Missense	proximal	1	no	20.835	20.696	EPSD	ICGC;COSMIC	20.673	Down-regulation
TK_Src_SrcA_SRC_Y	P22681	CBL	P12931	SRC	Y700	E696D	696	Missense	distal	-4	no	20.835	21.061	EPSD	ICGC;COSMIC	20.673	Up-regulation
TK_Src_SrcA_SRC_Y	P22681	CBL	P12931	SRC	Y700	E693D	693	Missense	distal	-7	no	20.835	20.806	EPSD	ICGC;COSMIC	20.673	Down-regulation
TK_Src_SrcA_SRC_Y	P22681	CBL	P12931	SRC	Y731	Y731H	731	Missense	central	0	yes	22.875	0.000	EPSD;PhosphoSitePlus	ICGC;COSMIC	20.673	Loss
TK_Src_SrcA_SRC_Y	P22681	CBL	P12931	SRC	Y774	G773E	773	Missense	proximal	-1	no	25.052	26.519	PhosphoSitePlus;EPSD	ICGC	20.673	Up-regulation
TK_Src_SrcA_SRC_Y	Q07954	LRP1	P12931	SRC	Y1937	W1938R	1938	Missense	proximal	1	no	22.490	22.574	EPSD	ICGC;COSMIC	20.673	Up-regulation
TK_Src_SrcA_SRC_Y	Q07954	LRP1	P12931	SRC	Y4507	M4512L	4512	Missense	distal	5	no	23.612	23.412	EPSD;PhosphoSitePlus	ICGC;COSMIC	20.673	Down-regulation
TK_Src_SrcA_SRC_Y	Q07954	LRP1	P12931	SRC	Y4507	T4509P	4509	Missense	proximal	2	no	23.612	23.263	EPSD;PhosphoSitePlus	ICGC;COSMIC	20.673	Down-regulation
TK_Src_SrcA_SRC_Y	Q16625	OCLN	P12931	SRC	Y29	P24L	24	Missense	distal	-5	no	21.526	21.370	EPSD	ICGC	20.673	Down-regulation
TK_Src_SrcA_SRC_Y	Q16625	OCLN	P12931	SRC	Y398	H397Y	397	Missense	proximal	-1	no	23.734	24.329	PhosphoSitePlus;EPSD	ICGC	20.673	Up-regulation
TK_Src_SrcA_SRC_Y	Q16625	OCLN	P12931	SRC	Y398	Y398F	398	Missense	central	0	yes	23.734	0.000	PhosphoSitePlus;EPSD	ICGC	20.673	Loss
TK_Src_SrcA_SRC_Y	Q99439	CNN2	P12931	SRC	Y12	E17D	17	Missense	distal	5	no	21.761	21.553	PhosphoSitePlus	ICGC	20.673	Down-regulation
TK_Src_SrcA_SRC_Y	Q99439	CNN2	P12931	SRC	Y12	S11L	11	Missense	proximal	-1	no	21.761	22.098	PhosphoSitePlus	ICGC;COSMIC	20.673	Up-regulation
TK_Src_SrcA_SRC_Y	Q969H4	CNKSR1	P12931	SRC	Y519	E516K	516	Missense	distal	-3	no	25.825	24.114	EPSD;PhosphoSitePlus	ICGC;COSMIC	20.673	Down-regulation
TK_Src_SrcA_SRC_Y	Q969H4	CNKSR1	P12931	SRC	Y665	E663G	663	Missense	proximal	-2	no	21.467	20.890	EPSD;PhosphoSitePlus	ICGC;COSMIC;CCLE	20.673	Down-regulation
TK_Src_SrcA_SRC_Y	P16591	FER	P12931	SRC	Y42	S44C	44	Missense	proximal	2	no	22.321	20.889	EPSD	ICGC;COSMIC	20.673	Down-regulation
TK_Src_SrcA_SRC_Y	P16591	FER	P12931	SRC	Y714	D710Y	710	Missense	distal	-4	no	28.525	27.531	PhosphoSitePlus	ICGC	20.673	Down-regulation
TK_Src_SrcA_SRC_Y	Q00610	CLTC	P12931	SRC	Y377	A380V	380	Missense	distal	3	no	20.794	21.364	EPSD	ICGC	20.673	Up-regulation
TK_Src_SrcA_SRC_Y	Q00610	CLTC	P12931	SRC	Y377	G375V	375	Missense	proximal	-2	no	20.794	19.518	EPSD	ICGC	20.673	Loss
TK_Src_SrcA_SRC_Y	Q00610	CLTC	P12931	SRC	Y377	A373S	373	Missense	distal	-4	no	20.794	21.189	EPSD	ICGC	20.673	Up-regulation
TK_Src_SrcA_SRC_Y	Q00610	CLTC	P12931	SRC	Y377	E379D	379	Missense	proximal	2	no	20.794	20.506	EPSD	ICGC;COSMIC	20.673	Loss
TK_Src_SrcA_SRC_Y	Q00610	CLTC	P12931	SRC	Y1137	V1141F	1141	Missense	distal	4	no	21.484	21.502	EPSD	ICGC	20.673	Up-regulation
TK_Src_SrcA_SRC_Y	Q00610	CLTC	P12931	SRC	Y1206	D1203G	1203	Missense	distal	-3	no	20.975	20.326	EPSD	ICGC;COSMIC	20.673	Loss
TK_Src_SrcA_SRC_Y	Q9NZC7	WWOX	P12931	SRC	Y33	E39K	39	Missense	distal	6	no	25.105	25.103	PhosphoSitePlus	ICGC;COSMIC	20.673	Down-regulation
TK_Src_SrcA_SRC_Y	Q9NZC7	WWOX	P12931	SRC	Y33	G30C	30	Missense	distal	-3	no	25.105	22.564	PhosphoSitePlus	ICGC	20.673	Down-regulation
TK_Src_SrcA_SRC_Y	Q9NZC7	WWOX	P12931	SRC	Y33	G30V	30	Missense	distal	-3	no	25.105	23.829	PhosphoSitePlus	ICGC	20.673	Down-regulation
TK_Src_SrcA_SRC_Y	Q9NZC7	WWOX	P12931	SRC	Y61	E64G	64	Missense	distal	3	no	20.541	20.820	EPSD	ICGC	20.673	Gain
TK_Src_SrcA_SRC_Y	P35637	FUS	P12931	SRC	Y239	G246C	246	Missense	distal	7	no	20.602	20.682	EPSD	ICGC	20.673	Gain
TK_Src_SrcA_SRC_Y	P04637	TP53	P12931	SRC	Y220	P219T	219	Missense	proximal	-1	no	22.082	21.825	EPSD;PhosphoSitePlus	ICGC;COSMIC	20.673	Down-regulation
TK_Src_SrcA_SRC_Y	P04637	TP53	P12931	SRC	Y220	H214D	214	Missense	distal	-6	no	22.082	22.419	EPSD;PhosphoSitePlus	ICGC;COSMIC	20.673	Up-regulation
TK_Src_SrcA_SRC_Y	P04637	TP53	P12931	SRC	Y220	Y220N	220	Missense	central	0	yes	22.082	0.000	EPSD;PhosphoSitePlus	ICGC;COSMIC	20.673	Loss
TK_Src_SrcA_SRC_Y	P04637	TP53	P12931	SRC	Y220	E221V	221	Missense	proximal	1	no	22.082	20.200	EPSD;PhosphoSitePlus	ICGC;COSMIC	20.673	Loss
TK_Src_SrcA_SRC_Y	P04637	TP53	P12931	SRC	Y220	E221K	221	Missense	proximal	1	no	22.082	19.687	EPSD;PhosphoSitePlus	ICGC;COSMIC	20.673	Loss
TK_Src_SrcA_SRC_Y	P04637	TP53	P12931	SRC	Y220	H214Y	214	Missense	distal	-6	no	22.082	22.251	EPSD;PhosphoSitePlus	ICGC;COSMIC	20.673	Up-regulation
TK_Src_SrcA_SRC_Y	P04637	TP53	P12931	SRC	Y220	P223R	223	Missense	distal	3	no	22.082	20.296	EPSD;PhosphoSitePlus	ICGC;COSMIC	20.673	Loss
TK_Src_SrcA_SRC_Y	P04637	TP53	P12931	SRC	Y220	E224A	224	Missense	distal	4	no	22.082	22.092	EPSD;PhosphoSitePlus	ICGC	20.673	Up-regulation
TK_Src_SrcA_SRC_Y	P04637	TP53	P12931	SRC	Y220	V217G	217	Missense	distal	-3	no	22.082	23.357	EPSD;PhosphoSitePlus	ICGC;COSMIC;CCLE	20.673	Up-regulation
TK_Src_SrcA_SRC_Y	P04637	TP53	P12931	SRC	Y220	S215T	215	Missense	distal	-5	no	22.082	21.773	EPSD;PhosphoSitePlus	ICGC;COSMIC	20.673	Down-regulation
TK_Src_SrcA_SRC_Y	Q13283	G3BP1	P12931	SRC	Y174	S180G	180	Missense	distal	6	no	21.073	21.093	EPSD	ICGC	20.673	Up-regulation
TK_Src_SrcA_SRC_Y	Q13283	G3BP1	P12931	SRC	Y174	V179F	179	Missense	distal	5	no	21.073	21.225	EPSD	ICGC;COSMIC	20.673	Up-regulation
TK_Src_SrcA_SRC_Y	P11802	CDK4	P12931	SRC	Y17	G15C	15	Missense	proximal	-2	no	22.818	20.965	PhosphoSitePlus	ICGC;COSMIC	20.673	Down-regulation
TK_Src_SrcA_SRC_Y	P35968	KDR	P12931	SRC	Y224	L228P	228	Missense	distal	4	no	20.745	20.716	EPSD	ICGC;COSMIC	20.673	Down-regulation
TK_Src_SrcA_SRC_Y	P35968	KDR	P12931	SRC	Y224	S229N	229	Missense	distal	5	no	20.745	20.744	EPSD	ICGC;COSMIC	20.673	Down-regulation
TK_Src_SrcA_SRC_Y	P35968	KDR	P12931	SRC	Y1054	A1050D	1050	Missense	distal	-4	no	20.168	21.510	EPSD	ICGC	20.673	Gain
TK_Src_SrcA_SRC_Y	P35968	KDR	P12931	SRC	Y1059	D1052H	1052	Missense	distal	-7	no	21.285	21.189	EPSD	ICGC;COSMIC	20.673	Down-regulation
TK_Src_SrcA_SRC_Y	P35968	KDR	P12931	SRC	Y1059	D1064N	1064	Missense	distal	5	no	21.285	21.443	EPSD	ICGC	20.673	Up-regulation
TK_Src_SrcA_SRC_Y	P35968	KDR	P12931	SRC	Y1175	Q1170K	1170	Missense	distal	-5	no	20.848	20.699	PhosphoSitePlus	ICGC	20.673	Down-regulation
TK_Src_SrcA_SRC_Y	P51813	BMX	P12931	SRC	Y216	K221N	221	Missense	distal	5	no	20.832	20.749	EPSD	ICGC;COSMIC	20.673	Down-regulation
TK_Src_SrcA_SRC_Y	P51813	BMX	P12931	SRC	Y216	S212R	212	Missense	distal	-4	no	20.832	21.102	EPSD	ICGC;COSMIC	20.673	Up-regulation
TK_Src_SrcA_SRC_Y	P51813	BMX	P12931	SRC	Y224	K221N	221	Missense	distal	-3	no	20.083	21.332	EPSD	ICGC;COSMIC	20.673	Gain
TK_Src_SrcA_SRC_Y	P51813	BMX	P12931	SRC	Y566	G571R	571	Missense	distal	5	no	25.486	25.304	PhosphoSitePlus	ICGC;COSMIC	20.673	Down-regulation
TK_Src_SrcA_SRC_Y	P00519	ABL1	P12931	SRC	Y172	R170G	170	Missense	proximal	-2	no	20.011	21.369	EPSD	ICGC;COSMIC	20.673	Gain
TK_Src_SrcA_SRC_Y	P00519	ABL1	P12931	SRC	Y185	E189G	189	Missense	distal	4	no	23.126	23.113	EPSD	ICGC;COSMIC	20.673	Down-regulation
TK_Src_SrcA_SRC_Y	P00519	ABL1	P12931	SRC	Y185	V186I	186	Missense	proximal	1	no	23.126	22.466	EPSD	ICGC;COSMIC	20.673	Down-regulation
TK_Src_SrcA_SRC_Y	P00519	ABL1	P12931	SRC	Y226	Y232C	232	Missense	distal	6	no	21.982	22.024	EPSD	ICGC;COSMIC	20.673	Up-regulation
TK_Src_SrcA_SRC_Y	P00519	ABL1	P12931	SRC	Y226	D233N	233	Missense	distal	7	no	21.982	21.980	EPSD	ICGC;COSMIC	20.673	Down-regulation
TK_Src_SrcA_SRC_Y	P00519	ABL1	P12931	SRC	Y226	D233Y	233	Missense	distal	7	no	21.982	22.000	EPSD	ICGC	20.673	Up-regulation
TK_Src_SrcA_SRC_Y	P00519	ABL1	P12931	SRC	Y253	H246Y	246	Missense	distal	-7	no	21.615	21.260	EPSD	ICGC;COSMIC	20.673	Down-regulation
TK_Src_SrcA_SRC_Y	P00519	ABL1	P12931	SRC	Y253	Y253N	253	Missense	central	0	yes	21.615	0.000	EPSD	ICGC;COSMIC	20.673	Loss
TK_Src_SrcA_SRC_Y	P00519	ABL1	P12931	SRC	Y253	G254W	254	Missense	proximal	1	no	21.615	20.537	EPSD	ICGC;COSMIC	20.673	Loss
TK_Src_SrcA_SRC_Y	P00519	ABL1	P12931	SRC	Y253	G250R	250	Missense	distal	-3	no	21.615	20.722	EPSD	ICGC;COSMIC	20.673	Down-regulation
TK_Src_SrcA_SRC_Y	P00519	ABL1	P12931	SRC	Y253	G254R	254	Missense	proximal	1	no	21.615	20.621	EPSD	ICGC;COSMIC	20.673	Loss
TK_Src_SrcA_SRC_Y	P00519	ABL1	P12931	SRC	Y257	Y253N	253	Missense	distal	-4	no	22.586	23.047	EPSD	ICGC;COSMIC	20.673	Up-regulation
TK_Src_SrcA_SRC_Y	P00519	ABL1	P12931	SRC	Y257	G254W	254	Missense	distal	-3	no	22.586	20.483	EPSD	ICGC;COSMIC	20.673	Loss
TK_Src_SrcA_SRC_Y	P00519	ABL1	P12931	SRC	Y257	G250R	250	Missense	distal	-7	no	22.586	23.207	EPSD	ICGC;COSMIC	20.673	Up-regulation
TK_Src_SrcA_SRC_Y	P00519	ABL1	P12931	SRC	Y257	G254R	254	Missense	distal	-3	no	22.586	21.693	EPSD	ICGC;COSMIC	20.673	Down-regulation
TK_Src_SrcA_SRC_Y	P14923	JUP	P12931	SRC	Y22	S24L	24	Missense	proximal	2	no	21.760	20.696	EPSD	ICGC;COSMIC	20.673	Down-regulation
TK_Src_SrcA_SRC_Y	P14923	JUP	P12931	SRC	Y74	M76I	76	Missense	proximal	2	no	21.511	20.581	EPSD	ICGC	20.673	Loss
TK_Src_SrcA_SRC_Y	P14923	JUP	P12931	SRC	Y324	R320C	320	Missense	distal	-4	no	23.020	21.421	EPSD	ICGC	20.673	Down-regulation
TK_Src_SrcA_SRC_Y	P14923	JUP	P12931	SRC	Y324	M319I	319	Missense	distal	-5	no	23.020	23.130	EPSD	ICGC;COSMIC	20.673	Up-regulation
TK_Src_SrcA_SRC_Y	P14923	JUP	P12931	SRC	Y644	R651H	651	Missense	distal	7	no	20.870	20.856	PhosphoSitePlus	ICGC;COSMIC	20.673	Down-regulation
TK_Src_SrcA_SRC_Y	P14923	JUP	P12931	SRC	Y644	N638K	638	Missense	distal	-6	no	20.870	20.971	PhosphoSitePlus	ICGC;COSMIC	20.673	Up-regulation
TK_Src_SrcA_SRC_Y	Q8WWM7	ATXN2L	P12931	SRC	Y118	F114C	114	Missense	distal	-4	no	21.721	21.310	EPSD	ICGC	20.673	Down-regulation
TK_Src_SrcA_SRC_Y	Q8WWM7	ATXN2L	P12931	SRC	Y145	K138N	138	Missense	distal	-7	no	21.256	21.310	EPSD	ICGC;COSMIC	20.673	Up-regulation
TK_Src_SrcA_SRC_Y	Q8WWM7	ATXN2L	P12931	SRC	Y241	M247I	247	Missense	distal	6	no	21.503	21.481	EPSD	ICGC;COSMIC	20.673	Down-regulation
TK_Src_SrcA_SRC_Y	Q8WWM7	ATXN2L	P12931	SRC	Y349	R355Q	355	Missense	distal	6	no	20.848	20.865	EPSD	ICGC;COSMIC	20.673	Up-regulation
TK_Src_SrcA_SRC_Y	Q8WWM7	ATXN2L	P12931	SRC	Y349	G347W	347	Missense	proximal	-2	no	20.848	18.540	EPSD	ICGC;COSMIC	20.673	Loss
TK_Src_SrcA_SRC_Y	Q13017	ARHGAP5	P12931	SRC	Y630	R635W	635	Missense	distal	5	no	24.121	24.712	EPSD	ICGC;COSMIC;GDSC	20.673	Up-regulation
TK_Src_SrcA_SRC_Y	Q13017	ARHGAP5	P12931	SRC	Y991	A987V	987	Missense	distal	-4	no	21.393	21.259	EPSD	ICGC;COSMIC	20.673	Down-regulation
TK_Src_SrcA_SRC_Y	Q13017	ARHGAP5	P12931	SRC	Y991	S992I	992	Missense	proximal	1	no	21.393	19.949	EPSD	ICGC	20.673	Loss
TK_Src_SrcA_SRC_Y	Q13017	ARHGAP5	P12931	SRC	Y991	Y991C	991	Missense	central	0	yes	21.393	0.000	EPSD	ICGC;COSMIC	20.673	Loss
TK_Src_SrcA_SRC_Y	Q13017	ARHGAP5	P12931	SRC	Y1019	P1020S	1020	Missense	proximal	1	no	19.490	21.635	EPSD	ICGC	20.673	Gain
TK_Src_SrcA_SRC_Y	Q13017	ARHGAP5	P12931	SRC	Y1091	M1085V	1085	Missense	distal	-6	no	21.295	21.586	EPSD	ICGC;COSMIC	20.673	Up-regulation
TK_Src_SrcA_SRC_Y	Q13017	ARHGAP5	P12931	SRC	Y1091	P1087L	1087	Missense	distal	-4	no	21.295	20.660	EPSD	ICGC;COSMIC	20.673	Loss
TK_Src_SrcA_SRC_Y	Q13017	ARHGAP5	P12931	SRC	Y1109	E1107D	1107	Missense	proximal	-2	no	23.618	23.331	PhosphoSitePlus	ICGC;COSMIC	20.673	Down-regulation
TK_Src_SrcA_SRC_Y	Q13017	ARHGAP5	P12931	SRC	Y1109	S1105F	1105	Missense	distal	-4	no	23.618	22.699	PhosphoSitePlus	ICGC;COSMIC	20.673	Down-regulation
TK_Src_SrcA_SRC_Y	Q13017	ARHGAP5	P12931	SRC	Y1296	C1291F	1291	Missense	distal	-5	no	20.607	21.087	EPSD	ICGC	20.673	Gain
TK_Src_SrcA_SRC_Y	Q13017	ARHGAP5	P12931	SRC	Y1296	R1297S	1297	Missense	proximal	1	no	20.607	21.486	EPSD	ICGC;COSMIC	20.673	Gain
TK_Src_SrcA_SRC_Y	P12956	XRCC6	P12931	SRC	Y30	K31E	31	Missense	proximal	1	no	20.295	22.689	EPSD	ICGC;COSMIC	20.673	Gain
TK_Src_SrcA_SRC_Y	P12956	XRCC6	P12931	SRC	Y322	S324N	324	Missense	proximal	2	no	21.247	21.000	EPSD	ICGC;COSMIC	20.673	Down-regulation
TK_Src_SrcA_SRC_Y	Q6UN15	FIP1L1	P12931	SRC	Y27	V33L	33	Missense	distal	6	no	21.068	21.086	EPSD	ICGC	20.673	Up-regulation
TK_Src_SrcA_SRC_Y	Q6UN15	FIP1L1	P12931	SRC	Y27	D32Y	32	Missense	distal	5	no	21.068	21.640	EPSD	ICGC	20.673	Up-regulation
TK_Src_SrcA_SRC_Y	Q6UN15	FIP1L1	P12931	SRC	Y27	W31L	31	Missense	distal	4	no	21.068	21.129	EPSD	ICGC	20.673	Up-regulation
TK_Src_SrcA_SRC_Y	Q6UN15	FIP1L1	P12931	SRC	Y110	S112I	112	Missense	proximal	2	no	21.781	20.445	PhosphoSitePlus	ICGC	20.673	Loss
TK_Src_SrcA_SRC_Y	Q6UN15	FIP1L1	P12931	SRC	Y110	Y113C	113	Missense	distal	3	no	21.781	20.706	PhosphoSitePlus	ICGC;COSMIC	20.673	Down-regulation
TK_Src_SrcA_SRC_Y	Q6UN15	FIP1L1	P12931	SRC	Y113	S112I	112	Missense	proximal	-1	no	19.746	20.819	EPSD	ICGC	20.673	Gain
TK_Src_SrcA_SRC_Y	Q6UN15	FIP1L1	P12931	SRC	Y505	R506I	506	Missense	proximal	1	no	21.632	21.067	EPSD	ICGC	20.673	Down-regulation
TK_Src_SrcA_SRC_Y	Q6UN15	FIP1L1	P12931	SRC	Y505	R508K	508	Missense	distal	3	no	21.632	21.301	EPSD	ICGC	20.673	Down-regulation
TK_Src_SrcA_SRC_Y	Q6UN15	FIP1L1	P12931	SRC	Y505	R508M	508	Missense	distal	3	no	21.632	22.927	EPSD	ICGC;COSMIC	20.673	Up-regulation
TK_Src_SrcA_SRC_Y	P08727	KRT19	P12931	SRC	Y130	Y127S	127	Missense	distal	-3	no	23.627	24.548	EPSD	ICGC;COSMIC	20.673	Up-regulation
TK_Src_SrcA_SRC_Y	P08727	KRT19	P12931	SRC	Y130	Y127H	127	Missense	distal	-3	no	23.627	23.439	EPSD	ICGC;COSMIC	20.673	Down-regulation
TK_Src_SrcA_SRC_Y	P08727	KRT19	P12931	SRC	Y130	D126A	126	Missense	distal	-4	no	23.627	22.285	EPSD	ICGC;COSMIC	20.673	Down-regulation
TK_Src_SrcA_SRC_Y	P08727	KRT19	P12931	SRC	Y131	Y127S	127	Missense	distal	-4	no	23.221	23.268	EPSD	ICGC;COSMIC	20.673	Up-regulation
TK_Src_SrcA_SRC_Y	P08727	KRT19	P12931	SRC	Y131	Y127H	127	Missense	distal	-4	no	23.221	23.054	EPSD	ICGC;COSMIC	20.673	Down-regulation
TK_Src_SrcA_SRC_Y	P08727	KRT19	P12931	SRC	Y131	D126A	126	Missense	distal	-5	no	23.221	23.039	EPSD	ICGC;COSMIC	20.673	Down-regulation
TK_Src_SrcA_SRC_Y	P08727	KRT19	P12931	SRC	Y131	R138L	138	Missense	distal	7	no	23.221	23.196	EPSD	ICGC;COSMIC	20.673	Down-regulation
TK_Src_SrcA_SRC_Y	P08727	KRT19	P12931	SRC	Y256	E261K	261	Missense	distal	5	no	20.885	20.918	EPSD	ICGC	20.673	Up-regulation
TK_Src_SrcA_SRC_Y	P08727	KRT19	P12931	SRC	Y391	E388K	388	Missense	distal	-3	no	22.099	20.388	PhosphoSitePlus	ICGC;COSMIC	20.673	Loss
TK_Src_SrcA_SRC_Y	P08727	KRT19	P12931	SRC	Y391	Q387R	387	Missense	distal	-4	no	22.099	22.478	PhosphoSitePlus	ICGC;COSMIC	20.673	Up-regulation
TK_Src_SrcA_SRC_Y	Q14721	KCNB1	P12931	SRC	Y128	L129P	129	Missense	proximal	1	no	21.700	21.100	PhosphoSitePlus	ICGC;COSMIC	20.673	Down-regulation
TK_Src_SrcA_SRC_Y	Q14721	KCNB1	P12931	SRC	Y128	A135D	135	Missense	distal	7	no	21.700	21.680	PhosphoSitePlus	ICGC	20.673	Down-regulation
TK_Src_SrcA_SRC_Y	Q14721	KCNB1	P12931	SRC	Y128	Q134K	134	Missense	distal	6	no	21.700	21.716	PhosphoSitePlus	ICGC	20.673	Up-regulation
TK_Src_SrcA_SRC_Y	Q14721	KCNB1	P12931	SRC	Y128	D125E	125	Missense	distal	-3	no	21.700	21.655	PhosphoSitePlus	ICGC	20.673	Down-regulation
TK_Src_SrcA_SRC_Y	Q14721	KCNB1	P12931	SRC	Y128	E130D	130	Missense	proximal	2	no	21.700	21.412	PhosphoSitePlus	ICGC;COSMIC	20.673	Down-regulation
TK_Src_SrcA_SRC_Y	O15259	NPHP1	P12931	SRC	Y46	Q47K	47	Missense	proximal	1	no	21.083	19.673	EPSD	ICGC	20.673	Loss
TK_Src_SrcA_SRC_Y	O15259	NPHP1	P12931	SRC	Y46	Q43K	43	Missense	distal	-3	no	21.083	20.251	EPSD	ICGC	20.673	Loss
TK_Src_SrcA_SRC_Y	Q9UN19	DAPP1	P12931	SRC	Y139	V142A	142	Missense	distal	3	no	23.548	22.978	PhosphoSitePlus	ICGC;COSMIC	20.673	Down-regulation
TK_Src_SrcA_SRC_Y	Q9UN19	DAPP1	P12931	SRC	Y139	I138V	138	Missense	proximal	-1	no	23.548	23.923	PhosphoSitePlus	ICGC;COSMIC	20.673	Up-regulation
TK_Src_SrcA_SRC_Y	P11511	CYP19A1	P12931	SRC	Y361	P368S	368	Missense	distal	7	no	22.879	22.859	PhosphoSitePlus	ICGC;COSMIC	20.673	Down-regulation
TK_Src_SrcA_SRC_Y	P98161	PKD1	P12931	SRC	Y2336	S2339R	2339	Missense	distal	3	no	21.526	20.479	EPSD	ICGC;COSMIC	20.673	Loss
TK_Src_SrcA_SRC_Y	P10636	MAPT	P12931	SRC	Y18	A15T	15	Missense	distal	-3	no	21.842	22.037	PhosphoSitePlus	ICGC;COSMIC	20.673	Up-regulation
TK_Src_SrcA_SRC_Y	P10636	MAPT	P12931	SRC	Y18	M11I	11	Missense	distal	-7	no	21.842	22.128	PhosphoSitePlus	ICGC	20.673	Up-regulation
TK_Src_SrcA_SRC_Y	P10636	MAPT	P12931	SRC	Y29	D34Y	34	Missense	distal	5	no	20.502	21.074	EPSD	ICGC;COSMIC	20.673	Gain
TK_Src_SrcA_SRC_Y	P10636	MAPT	P12931	SRC	Y514	G521R	521	Missense	distal	7	no	21.389	21.396	EPSD	ICGC;COSMIC	20.673	Up-regulation
TK_Src_SrcA_SRC_Y	P78352	DLG4	P12931	SRC	Y236	A230T	230	Missense	distal	-6	no	21.012	21.049	EPSD	ICGC;COSMIC	20.673	Up-regulation
TK_Src_SrcA_SRC_Y	P78352	DLG4	P12931	SRC	Y236	N234S	234	Missense	proximal	-2	no	21.012	20.390	EPSD	ICGC;COSMIC	20.673	Loss
TK_Src_SrcA_SRC_Y	P42224	STAT1	P12931	SRC	Y68	L73F	73	Missense	distal	5	no	22.217	22.274	EPSD	ICGC;COSMIC	20.673	Up-regulation
TK_Src_SrcA_SRC_Y	Q9NR80	ARHGEF4	P12931	SRC	Y165	G159E	159	Missense	distal	-6	no	23.635	23.864	EPSD	ICGC;COSMIC	20.673	Up-regulation
TK_Src_SrcA_SRC_Y	Q9NR80	ARHGEF4	P12931	SRC	Y165	Y165C	165	Missense	central	0	yes	23.635	0.000	EPSD	ICGC	20.673	Loss
TK_Src_SrcA_SRC_Y	Q9NR80	ARHGEF4	P12931	SRC	Y165	D167N	167	Missense	proximal	2	no	23.635	23.848	EPSD	ICGC;COSMIC	20.673	Up-regulation
TK_Src_SrcA_SRC_Y	Q9NR80	ARHGEF4	P12931	SRC	Y165	V158L	158	Missense	distal	-7	no	23.635	23.671	EPSD	ICGC	20.673	Up-regulation
TK_Src_SrcA_SRC_Y	Q9NR80	ARHGEF4	P12931	SRC	Y165	G159W	159	Missense	distal	-6	no	23.635	23.370	EPSD	ICGC;COSMIC;CCLE	20.673	Down-regulation
TK_Src_SrcA_SRC_Y	Q9NR80	ARHGEF4	P12931	SRC	Y165	L164M	164	Missense	proximal	-1	no	23.635	23.139	EPSD	ICGC;COSMIC	20.673	Down-regulation
TK_Src_SrcA_SRC_Y	Q9NR80	ARHGEF4	P12931	SRC	Y175	G182V	182	Missense	distal	7	no	22.527	22.562	EPSD	ICGC;COSMIC	20.673	Up-regulation
TK_Src_SrcA_SRC_Y	Q9NR80	ARHGEF4	P12931	SRC	Y175	G181V	181	Missense	distal	6	no	22.527	22.521	EPSD	ICGC;COSMIC	20.673	Down-regulation
TK_Src_SrcA_SRC_Y	Q9NR80	ARHGEF4	P12931	SRC	Y175	H174P	174	Missense	proximal	-1	no	22.527	22.297	EPSD	ICGC;COSMIC	20.673	Down-regulation
TK_Src_SrcA_SRC_Y	P50281	MMP14	P12931	SRC	Y138	R145C	145	Missense	distal	7	no	22.285	22.357	EPSD	ICGC	20.673	Up-regulation
TK_Src_SrcA_SRC_Y	P50281	MMP14	P12931	SRC	Y138	R145H	145	Missense	distal	7	no	22.285	22.271	EPSD	ICGC;COSMIC	20.673	Down-regulation
TK_Src_SrcA_SRC_Y	P12235	SLC25A4	P12931	SRC	Y174	G176C	176	Missense	proximal	2	no	20.732	20.428	EPSD	ICGC	20.673	Loss
TK_Src_SrcA_SRC_Y	P12235	SLC25A4	P12931	SRC	Y195	R188K	188	Missense	distal	-7	no	21.909	21.576	PhosphoSitePlus	ICGC;COSMIC	20.673	Down-regulation
CMGC_CDK_CDK2_CDK3_ST	Q5TKA1	LIN9	Q00526	CDK3	T39	S35Y	35	Missense	distal	-4	no	10.887	9.695	EPSD	ICGC	5.767	Down-regulation
CMGC_CDK_CDK2_CDK3_ST	Q5TKA1	LIN9	Q00526	CDK3	T39	K43N	43	Missense	distal	4	no	10.887	10.900	EPSD	ICGC	5.767	Up-regulation
CMGC_CDK_CDK2_CDK3_ST	Q5TKA1	LIN9	Q00526	CDK3	S58	E52A	52	Missense	distal	-6	no	5.800	5.528	EPSD	ICGC	5.767	Loss
CMGC_CDK_CDK2_CDK3_ST	Q5TKA1	LIN9	Q00526	CDK3	S76	R75C	75	Missense	proximal	-1	no	6.734	6.727	EPSD	ICGC	5.767	Down-regulation
CMGC_CDK_CDK2_CDK3_ST	Q5TKA1	LIN9	Q00526	CDK3	S76	R75G	75	Missense	proximal	-1	no	6.734	6.725	EPSD	ICGC	5.767	Down-regulation
CMGC_CDK_CDK2_CDK3_ST	Q5TKA1	LIN9	Q00526	CDK3	S76	R75H	75	Missense	proximal	-1	no	6.734	6.728	EPSD	ICGC	5.767	Down-regulation
CMGC_CDK_CDK2_CDK3_ST	Q14934	NFATC4	Q00526	CDK3	S73	R77H	77	Missense	distal	4	no	9.406	9.484	EPSD	ICGC;COSMIC	5.767	Up-regulation
CMGC_CDK_CDK2_CDK3_ST	Q14934	NFATC4	Q00526	CDK3	S73	P74L	74	Missense	proximal	1	no	9.406	2.661	EPSD	ICGC;COSMIC	5.767	Loss
CMGC_CDK_CDK2_CDK3_ST	Q14934	NFATC4	Q00526	CDK3	S295	P297L	297	Missense	proximal	2	no	7.866	7.953	EPSD	ICGC;COSMIC	5.767	Up-regulation
CMGC_CDK_CDK2_CDK3_ST	Q14934	NFATC4	Q00526	CDK3	S311	P314L	314	Missense	distal	3	no	13.286	11.088	EPSD	ICGC;COSMIC	5.767	Down-regulation
CMGC_CDK_CDK2_CDK3_ST	Q14934	NFATC4	Q00526	CDK3	S395	P396S	396	Missense	proximal	1	no	8.450	3.386	EPSD	ICGC;COSMIC	5.767	Loss
CMGC_CDK_CDK2_CDK3_ST	Q14934	NFATC4	Q00526	CDK3	S592	V598F	598	Missense	distal	6	no	8.336	8.381	EPSD	ICGC;COSMIC	5.767	Up-regulation
CMGC_CDK_CDK2_CDK3_ST	Q14934	NFATC4	Q00526	CDK3	S592	V588A	588	Missense	distal	-4	no	8.336	8.629	EPSD	ICGC;COSMIC	5.767	Up-regulation
CMGC_CDK_CDK2_CDK3_ST	Q14934	NFATC4	Q00526	CDK3	S716	F715C	715	Missense	proximal	-1	no	10.253	10.249	EPSD	ICGC;COSMIC	5.767	Down-regulation
CMGC_CDK_CDK2_CDK3_ST	Q14934	NFATC4	Q00526	CDK3	S819	P820S	820	Missense	proximal	1	no	8.863	3.799	EPSD	ICGC;COSMIC	5.767	Loss
CMGC_CDK_CDK2_CDK3_ST	P03372	ESR1	Q00526	CDK3	S46	V51M	51	Missense	distal	5	no	6.525	6.713	EPSD	ICGC	5.767	Up-regulation
CMGC_CDK_CDK2_CDK3_ST	P03372	ESR1	Q00526	CDK3	S46	D45E	45	Missense	proximal	-1	no	6.525	6.529	EPSD	ICGC;COSMIC	5.767	Up-regulation
CMGC_CDK_CDK2_CDK3_ST	P03372	ESR1	Q00526	CDK3	S102	P99S	99	Missense	distal	-3	no	6.023	6.062	EPSD	ICGC	5.767	Up-regulation
CMGC_CDK_CDK2_CDK3_ST	P03372	ESR1	Q00526	CDK3	S102	G95W	95	Missense	distal	-7	no	6.023	5.886	EPSD	ICGC	5.767	Down-regulation
CMGC_CDK_CDK2_CDK3_ST	P03372	ESR1	Q00526	CDK3	S102	S102N	102	Missense	central	0	yes	6.023	0.000	EPSD	ICGC;COSMIC	5.767	Loss
CMGC_CDK_CDK2_CDK3_ST	P03372	ESR1	Q00526	CDK3	S102	N101S	101	Missense	proximal	-1	no	6.023	6.019	EPSD	ICGC;COSMIC	5.767	Down-regulation
CMGC_CDK_CDK2_CDK3_ST	P03372	ESR1	Q00526	CDK3	S104	P99S	99	Missense	distal	-5	no	14.135	13.569	EPSD;PhosphoSitePlus	ICGC	5.767	Down-regulation
CMGC_CDK_CDK2_CDK3_ST	P03372	ESR1	Q00526	CDK3	S104	S102N	102	Missense	proximal	-2	no	14.135	14.300	EPSD;PhosphoSitePlus	ICGC;COSMIC	5.767	Up-regulation
CMGC_CDK_CDK2_CDK3_ST	P03372	ESR1	Q00526	CDK3	S104	N101S	101	Missense	distal	-3	no	14.135	14.050	EPSD;PhosphoSitePlus	ICGC;COSMIC	5.767	Down-regulation
CMGC_CDK_CDK2_CDK3_ST	P03372	ESR1	Q00526	CDK3	S106	P99S	99	Missense	distal	-7	no	13.716	13.730	EPSD;PhosphoSitePlus	ICGC	5.767	Up-regulation
CMGC_CDK_CDK2_CDK3_ST	P03372	ESR1	Q00526	CDK3	S106	S102N	102	Missense	distal	-4	no	13.716	13.224	EPSD;PhosphoSitePlus	ICGC;COSMIC	5.767	Down-regulation
CMGC_CDK_CDK2_CDK3_ST	P03372	ESR1	Q00526	CDK3	S106	N101S	101	Missense	distal	-5	no	13.716	13.241	EPSD;PhosphoSitePlus	ICGC;COSMIC	5.767	Down-regulation
CMGC_CDK_CDK2_CDK3_ST	P03372	ESR1	Q00526	CDK3	S106	H112P	112	Missense	distal	6	no	13.716	13.705	EPSD;PhosphoSitePlus	ICGC;COSMIC	5.767	Down-regulation
CMGC_CDK_CDK2_CDK3_ST	P03372	ESR1	Q00526	CDK3	S118	H112P	112	Missense	distal	-6	no	13.277	12.806	PhosphoSitePlus;EPSD	ICGC;COSMIC	5.767	Down-regulation
CMGC_CDK_CDK2_CDK3_ST	P03372	ESR1	Q00526	CDK3	S118	P114L	114	Missense	distal	-4	no	13.277	12.627	PhosphoSitePlus;EPSD	ICGC;COSMIC	5.767	Down-regulation
CMGC_CDK_CDK2_CDK3_ST	P03372	ESR1	Q00526	CDK3	S294	R300L	300	Missense	distal	6	no	9.470	9.452	EPSD	ICGC;COSMIC	5.767	Down-regulation
CMGC_CDK_CDK2_CDK3_ST	P03372	ESR1	Q00526	CDK3	S294	R300S	300	Missense	distal	6	no	9.470	9.413	EPSD	ICGC;COSMIC	5.767	Down-regulation
CMGC_CDK_CDK2_CDK3_ST	P03372	ESR1	Q00526	CDK3	S294	R300H	300	Missense	distal	6	no	9.470	9.461	EPSD	ICGC;COSMIC	5.767	Down-regulation
CMGC_CDK_CDK2_CDK3_ST	P03372	ESR1	Q00526	CDK3	S329	E330K	330	Missense	proximal	1	no	4.508	6.155	EPSD	ICGC;COSMIC	5.767	Gain
CMGC_CDK_CDK2_CDK3_ST	P46531	NOTCH1	Q00526	CDK3	T535	C537S	537	Missense	proximal	2	no	10.243	10.514	EPSD	ICGC;COSMIC	5.767	Up-regulation
CMGC_CDK_CDK2_CDK3_ST	P46531	NOTCH1	Q00526	CDK3	T1861	P1862S	1862	Missense	proximal	1	no	6.686	1.622	EPSD	ICGC	5.767	Loss
CMGC_CDK_CDK2_CDK3_ST	P46531	NOTCH1	Q00526	CDK3	T1861	P1862Q	1862	Missense	proximal	1	no	6.686	0.800	EPSD	ICGC;COSMIC	5.767	Loss
CMGC_CDK_CDK2_CDK3_ST	P46531	NOTCH1	Q00526	CDK3	S1941	L1948M	1948	Missense	distal	7	no	6.027	5.993	EPSD	ICGC;COSMIC	5.767	Down-regulation
CMGC_CDK_CDK2_CDK3_ST	P46531	NOTCH1	Q00526	CDK3	T1986	R1982L	1982	Missense	distal	-4	no	6.356	6.681	EPSD	ICGC;COSMIC	5.767	Up-regulation
CMGC_CDK_CDK2_CDK3_ST	P46531	NOTCH1	Q00526	CDK3	T1997	G1995V	1995	Missense	proximal	-2	no	7.292	7.088	EPSD	ICGC;COSMIC	5.767	Down-regulation
CMGC_CDK_CDK2_CDK3_ST	P46531	NOTCH1	Q00526	CDK3	T1997	L2001M	2001	Missense	distal	4	no	7.292	7.313	EPSD	ICGC	5.767	Up-regulation
CMGC_CDK_CDK2_CDK3_ST	P46531	NOTCH1	Q00526	CDK3	S2121	S2121R	2121	Missense	central	0	yes	9.030	0.000	EPSD	ICGC	5.767	Loss
CMGC_CDK_CDK2_CDK3_ST	P46531	NOTCH1	Q00526	CDK3	S2121	H2125Q	2125	Missense	distal	4	no	9.030	9.093	EPSD	ICGC;GDSC;CCLE	5.767	Up-regulation
CMGC_CDK_CDK2_CDK3_ST	P46531	NOTCH1	Q00526	CDK3	S2121	G2126R	2126	Missense	distal	5	no	9.030	9.037	EPSD	ICGC	5.767	Up-regulation
CMGC_CDK_CDK2_CDK3_ST	P46531	NOTCH1	Q00526	CDK3	T2132	H2125Q	2125	Missense	distal	-7	no	8.693	8.603	EPSD	ICGC;GDSC;CCLE	5.767	Down-regulation
CMGC_CDK_CDK2_CDK3_ST	P46531	NOTCH1	Q00526	CDK3	T2132	G2126R	2126	Missense	distal	-6	no	8.693	8.769	EPSD	ICGC	5.767	Up-regulation
CMGC_CDK_CDK2_CDK3_ST	P46531	NOTCH1	Q00526	CDK3	T2132	G2130W	2130	Missense	proximal	-2	no	8.693	8.564	EPSD	ICGC;COSMIC	5.767	Down-regulation
CMGC_CDK_CDK2_CDK3_ST	P46531	NOTCH1	Q00526	CDK3	T2132	P2138Q	2138	Missense	distal	6	no	8.693	8.691	EPSD	ICGC;COSMIC	5.767	Down-regulation
CMGC_CDK_CDK2_CDK3_ST	P46531	NOTCH1	Q00526	CDK3	S2136	G2130W	2130	Missense	distal	-6	no	8.121	7.770	EPSD	ICGC;COSMIC	5.767	Down-regulation
CMGC_CDK_CDK2_CDK3_ST	P46531	NOTCH1	Q00526	CDK3	S2136	P2138Q	2138	Missense	proximal	2	no	8.121	8.392	EPSD	ICGC;COSMIC	5.767	Up-regulation
CMGC_CDK_CDK2_CDK3_ST	P46531	NOTCH1	Q00526	CDK3	S2141	P2138Q	2138	Missense	distal	-3	no	11.515	11.610	EPSD	ICGC;COSMIC	5.767	Up-regulation
CMGC_CDK_CDK2_CDK3_ST	P46531	NOTCH1	Q00526	CDK3	S2163	G2165V	2165	Missense	proximal	2	no	6.163	6.378	EPSD	ICGC;COSMIC	5.767	Up-regulation
CMGC_CDK_CDK2_CDK3_ST	P46531	NOTCH1	Q00526	CDK3	S2215	P2216T	2216	Missense	proximal	1	no	10.376	4.171	EPSD	ICGC	5.767	Loss
CMGC_CDK_CDK2_CDK3_ST	P46531	NOTCH1	Q00526	CDK3	S2215	L2218R	2218	Missense	distal	3	no	10.376	9.974	EPSD	ICGC	5.767	Down-regulation
CMGC_CDK_CDK2_CDK3_ST	P46531	NOTCH1	Q00526	CDK3	S2221	P2216T	2216	Missense	distal	-5	no	11.378	11.486	EPSD	ICGC	5.767	Up-regulation
CMGC_CDK_CDK2_CDK3_ST	P46531	NOTCH1	Q00526	CDK3	S2221	L2218R	2218	Missense	distal	-3	no	11.378	11.372	EPSD	ICGC	5.767	Down-regulation
CMGC_CDK_CDK2_CDK3_ST	P46531	NOTCH1	Q00526	CDK3	T2511	P2512L	2512	Missense	proximal	1	no	14.773	8.028	EPSD;PhosphoSitePlus	ICGC;COSMIC	5.767	Down-regulation
CMGC_CDK_CDK2_CDK3_ST	P46531	NOTCH1	Q00526	CDK3	T2511	S2516F	2516	Missense	distal	5	no	14.773	15.089	EPSD;PhosphoSitePlus	ICGC	5.767	Up-regulation
CMGC_CDK_CDK2_CDK3_ST	P46531	NOTCH1	Q00526	CDK3	T2511	P2512T	2512	Missense	proximal	1	no	14.773	8.568	EPSD;PhosphoSitePlus	ICGC;COSMIC	5.767	Down-regulation
CMGC_CDK_CDK2_CDK3_ST	P46531	NOTCH1	Q00526	CDK3	S2513	P2512L	2512	Missense	proximal	-1	no	10.776	10.792	PhosphoSitePlus;EPSD	ICGC;COSMIC	5.767	Up-regulation
CMGC_CDK_CDK2_CDK3_ST	P46531	NOTCH1	Q00526	CDK3	S2513	S2516F	2516	Missense	distal	3	no	10.776	10.398	PhosphoSitePlus;EPSD	ICGC	5.767	Down-regulation
CMGC_CDK_CDK2_CDK3_ST	P46531	NOTCH1	Q00526	CDK3	S2513	P2512T	2512	Missense	proximal	-1	no	10.776	10.780	PhosphoSitePlus;EPSD	ICGC;COSMIC	5.767	Up-regulation
CMGC_CDK_CDK2_CDK3_ST	P46531	NOTCH1	Q00526	CDK3	S2516	P2512L	2512	Missense	distal	-4	no	12.861	12.211	EPSD;PhosphoSitePlus	ICGC;COSMIC	5.767	Down-regulation
CMGC_CDK_CDK2_CDK3_ST	P46531	NOTCH1	Q00526	CDK3	S2516	S2516F	2516	Missense	central	0	yes	12.861	0.000	EPSD;PhosphoSitePlus	ICGC	5.767	Loss
CMGC_CDK_CDK2_CDK3_ST	P46531	NOTCH1	Q00526	CDK3	S2516	P2512T	2512	Missense	distal	-4	no	12.861	12.848	EPSD;PhosphoSitePlus	ICGC;COSMIC	5.767	Down-regulation
CMGC_CDK_CDK2_CDK3_ST	P05412	JUN	Q00526	CDK3	S63	K70T	70	Missense	distal	7	no	13.865	13.904	EPSD;PhosphoSitePlus	ICGC;COSMIC	5.767	Up-regulation
CMGC_CDK_CDK2_CDK3_ST	P05412	JUN	Q00526	CDK3	S73	A72E	72	Missense	proximal	-1	no	13.846	13.850	PhosphoSitePlus;EPSD	ICGC;COSMIC	5.767	Up-regulation
CMGC_CDK_CDK2_CDK3_ST	P05412	JUN	Q00526	CDK3	S73	K70T	70	Missense	distal	-3	no	13.846	13.931	PhosphoSitePlus;EPSD	ICGC;COSMIC	5.767	Up-regulation
CMGC_CDK_CDK2_CDK3_ST	P05412	JUN	Q00526	CDK3	T91	T93N	93	Missense	proximal	2	no	8.463	8.449	EPSD	ICGC	5.767	Down-regulation
CMGC_CDK_CDK2_CDK3_ST	P05412	JUN	Q00526	CDK3	T91	L98R	98	Missense	distal	7	no	8.463	8.466	EPSD	ICGC	5.767	Up-regulation
CMGC_CDK_CDK2_CDK3_ST	P05412	JUN	Q00526	CDK3	T93	T93N	93	Missense	central	0	yes	8.816	0.000	EPSD	ICGC	5.767	Loss
CMGC_CDK_CDK2_CDK3_ST	P05412	JUN	Q00526	CDK3	T93	L98R	98	Missense	distal	5	no	8.816	8.854	EPSD	ICGC	5.767	Up-regulation
CMGC_CDK_CDK2_CDK3_ST	P05412	JUN	Q00526	CDK3	S243	T239K	239	Missense	distal	-4	no	6.622	6.203	EPSD	ICGC	5.767	Down-regulation
CMGC_CDK_CDK2_CDK3_ST	P18846	ATF1	Q00526	CDK3	S41	Q42K	42	Missense	proximal	1	no	4.629	6.159	EPSD	ICGC;COSMIC	5.767	Gain
CMGC_CDK_CDK2_CDK3_ST	P18846	ATF1	Q00526	CDK3	S50	S44A	44	Missense	distal	-6	no	7.244	7.609	EPSD	ICGC;COSMIC	5.767	Up-regulation
CMGC_CDK_CDK2_CDK3_ST	P18846	ATF1	Q00526	CDK3	S63	L68V	68	Missense	distal	5	no	14.522	14.295	PhosphoSitePlus	ICGC;COSMIC	5.767	Down-regulation
CMGC_CDK_CDK2_CDK3_ST	P18846	ATF1	Q00526	CDK3	S63	D70Y	70	Missense	distal	7	no	14.522	14.530	PhosphoSitePlus	ICGC;COSMIC	5.767	Up-regulation
CMGC_CDK_CDK2_CDK3_ST	P18846	ATF1	Q00526	CDK3	S63	R61H	61	Missense	proximal	-2	no	14.522	14.418	PhosphoSitePlus	ICGC;COSMIC	5.767	Down-regulation
CMGC_CDK_CDK2_CDK3_ST	P18846	ATF1	Q00526	CDK3	S63	Y64C	64	Missense	proximal	1	no	14.522	12.417	PhosphoSitePlus	ICGC;COSMIC	5.767	Down-regulation
CMGC_CDK_CDK2_CDK3_ST	P18846	ATF1	Q00526	CDK3	S72	L68V	68	Missense	distal	-4	no	7.813	8.508	EPSD	ICGC;COSMIC	5.767	Up-regulation
CMGC_CDK_CDK2_CDK3_ST	P18846	ATF1	Q00526	CDK3	S72	D70Y	70	Missense	proximal	-2	no	7.813	7.910	EPSD	ICGC;COSMIC	5.767	Up-regulation
CMGC_CDK_CDK2_CDK3_ST	P18846	ATF1	Q00526	CDK3	S72	L71I	71	Missense	proximal	-1	no	7.813	7.809	EPSD	ICGC;COSMIC	5.767	Down-regulation
CMGC_CDK_CDK2_CDK3_ST	Q12800	TFCP2	Q00526	CDK3	S54	P57S	57	Missense	distal	3	no	6.933	4.770	EPSD	ICGC;COSMIC	5.767	Loss
CMGC_CDK_CDK2_CDK3_ST	Q12800	TFCP2	Q00526	CDK3	S54	E52K	52	Missense	proximal	-2	no	6.933	6.869	EPSD	ICGC	5.767	Down-regulation
CMGC_CDK_CDK2_CDK3_ST	Q12800	TFCP2	Q00526	CDK3	T258	Y265F	265	Missense	distal	7	no	9.058	9.071	EPSD	ICGC;COSMIC	5.767	Up-regulation
CMGC_CDK_CDK2_CDK3_ST	Q12800	TFCP2	Q00526	CDK3	S289	V286A	286	Missense	distal	-3	no	10.601	10.576	EPSD	ICGC;COSMIC	5.767	Down-regulation
CMGC_CDK_CDK2_CDK3_ST	Q12800	TFCP2	Q00526	CDK3	S291	V286A	286	Missense	distal	-5	no	8.309	8.324	EPSD	ICGC;COSMIC	5.767	Up-regulation
CMGC_CDK_CDK2_CDK3_ST	Q12800	TFCP2	Q00526	CDK3	S291	S297F	297	Missense	distal	6	no	8.309	8.351	EPSD	ICGC;COSMIC	5.767	Up-regulation
CMGC_CDK_CDK2_CDK3_ST	Q12800	TFCP2	Q00526	CDK3	S309	G304E	304	Missense	distal	-5	no	14.086	14.032	PhosphoSitePlus	ICGC	5.767	Down-regulation
CMGC_CDK_CDK2_CDK3_ST	Q12800	TFCP2	Q00526	CDK3	S309	P310S	310	Missense	proximal	1	no	14.086	9.022	PhosphoSitePlus	ICGC;COSMIC	5.767	Down-regulation
CMGC_CDK_CDK2_CDK3_ST	Q8TDN4	CABLES1	Q00526	CDK3	S257	L263M	263	Missense	distal	6	no	7.462	7.463	EPSD	ICGC;COSMIC	5.767	Up-regulation
CMGC_CDK_CDK2_CDK3_ST	Q8TDN4	CABLES1	Q00526	CDK3	T374	G369R	369	Missense	distal	-5	no	6.136	6.481	EPSD	ICGC	5.767	Up-regulation
CMGC_CDK_CDK2_CDK3_ST	P06400	RB1	Q00526	CDK3	S230	D224E	224	Missense	distal	-6	no	7.509	7.767	EPSD	ICGC;COSMIC	5.767	Up-regulation
CMGC_CDK_CDK2_CDK3_ST	P06400	RB1	Q00526	CDK3	S249	R251L	251	Missense	proximal	2	no	9.420	9.220	EPSD	ICGC	5.767	Down-regulation
CMGC_CDK_CDK2_CDK3_ST	P06400	RB1	Q00526	CDK3	S249	G256C	256	Missense	distal	7	no	9.420	9.435	EPSD	ICGC	5.767	Up-regulation
CMGC_CDK_CDK2_CDK3_ST	P06400	RB1	Q00526	CDK3	T252	R251L	251	Missense	proximal	-1	no	6.845	6.846	EPSD	ICGC	5.767	Up-regulation
CMGC_CDK_CDK2_CDK3_ST	P06400	RB1	Q00526	CDK3	T252	G256C	256	Missense	distal	4	no	6.845	6.935	EPSD	ICGC	5.767	Up-regulation
CMGC_CDK_CDK2_CDK3_ST	P06400	RB1	Q00526	CDK3	S567	L572I	572	Missense	distal	5	no	7.495	7.538	EPSD	ICGC;COSMIC	5.767	Up-regulation
CMGC_CDK_CDK2_CDK3_ST	P06400	RB1	Q00526	CDK3	S567	D571Y	571	Missense	distal	4	no	7.495	7.416	EPSD	ICGC	5.767	Down-regulation
CMGC_CDK_CDK2_CDK3_ST	P06400	RB1	Q00526	CDK3	S567	W563L	563	Missense	distal	-4	no	7.495	7.282	EPSD	ICGC	5.767	Down-regulation
CMGC_CDK_CDK2_CDK3_ST	P06400	RB1	Q00526	CDK3	S567	A562P	562	Missense	distal	-5	no	7.495	7.554	EPSD	ICGC;COSMIC;GDSC;CCLE	5.767	Up-regulation
CMGC_CDK_CDK2_CDK3_ST	P06400	RB1	Q00526	CDK3	S567	L564F	564	Missense	distal	-3	no	7.495	7.413	EPSD	ICGC	5.767	Down-regulation
CMGC_CDK_CDK2_CDK3_ST	P06400	RB1	Q00526	CDK3	S780	P783L	783	Missense	distal	3	no	9.001	6.803	EPSD	ICGC	5.767	Down-regulation
CMGC_CDK_CDK2_CDK3_ST	P06400	RB1	Q00526	CDK3	S788	P783L	783	Missense	distal	-5	no	7.305	8.304	EPSD	ICGC	5.767	Up-regulation
CMGC_CDK_CDK2_CDK3_ST	P06400	RB1	Q00526	CDK3	S795	L797S	797	Missense	proximal	2	no	7.086	7.530	EPSD	ICGC;COSMIC	5.767	Up-regulation
CMGC_CDK_CDK2_CDK3_ST	P06400	RB1	Q00526	CDK3	S795	G801E	801	Missense	distal	6	no	7.086	6.984	EPSD	ICGC	5.767	Down-regulation
CMGC_CDK_CDK2_CDK3_ST	P06400	RB1	Q00526	CDK3	S807	G801E	801	Missense	distal	-6	no	13.237	12.969	PhosphoSitePlus;EPSD	ICGC	5.767	Down-regulation
CMGC_CDK_CDK2_CDK3_ST	P06400	RB1	Q00526	CDK3	S866	K873E	873	Missense	distal	7	no	6.000	6.029	EPSD	ICGC;COSMIC	5.767	Up-regulation
CMGC_CDK_CDK2_CDK3_ST	P06400	RB1	Q00526	CDK3	S866	P871Q	871	Missense	distal	5	no	6.000	6.194	EPSD	ICGC;COSMIC	5.767	Up-regulation
Other_WNK_WNK2_ST	Q9UEW8	STK39	Q9Y3S1	WNK2	T224	N226Y	226	Missense	proximal	2	no	2.550	2.621	EPSD	ICGC;COSMIC	2.413	Up-regulation
Other_WNK_WNK2_ST	Q9UEW8	STK39	Q9Y3S1	WNK2	S371	G372V	372	Missense	proximal	1	no	7.282	7.454	EPSD;PhosphoSitePlus	ICGC	2.413	Up-regulation
Other_WNK_WNK2_ST	Q9UEW8	STK39	Q9Y3S1	WNK2	S385	E388K	388	Missense	distal	3	no	2.490	2.213	EPSD	ICGC;COSMIC	2.413	Loss
Other_WNK_WNK2_ST	Q9UEW8	STK39	Q9Y3S1	WNK2	S385	D387E	387	Missense	proximal	2	no	2.490	2.200	EPSD	ICGC	2.413	Loss
Other_WNK_WNK2_ST	Q9UEW8	STK39	Q9Y3S1	WNK2	S401	Q402K	402	Missense	proximal	1	no	2.221	2.477	EPSD	ICGC	2.413	Gain
Other_WNK_WNK2_ST	Q9H4A3	WNK1	Q9Y3S1	WNK2	T72	A70V	70	Missense	proximal	-2	no	3.150	3.154	EPSD	ICGC;COSMIC	2.413	Up-regulation
Other_WNK_WNK2_ST	Q9H4A3	WNK1	Q9Y3S1	WNK2	T72	G67E	67	Missense	distal	-5	no	3.150	3.310	EPSD	ICGC	2.413	Up-regulation
Other_WNK_WNK2_ST	Q9H4A3	WNK1	Q9Y3S1	WNK2	T72	R66S	66	Missense	distal	-6	no	3.150	1.792	EPSD	ICGC;GDSC;CCLE	2.413	Loss
Other_WNK_WNK2_ST	Q9H4A3	WNK1	Q9Y3S1	WNK2	S597	S596F	596	Missense	proximal	-1	no	2.940	2.631	EPSD	ICGC;COSMIC	2.413	Down-regulation
TK_Trk_NTRK2_Y	P22001	KCNA3	Q16620	NTRK2	Y485	Y485H	485	Missense	central	0	yes	0.000	0.000	EPSD	ICGC;COSMIC	0.000	Loss
AGC_RSK_MSK_RPS6KA4_ST	P16220	CREB1	O75676	RPS6KA4	S133	D140A	140	Missense	distal	7	no	9.316	9.250	PhosphoSitePlus	ICGC;COSMIC	2.457	Down-regulation
AGC_RSK_MSK_RPS6KA4_ST	P16220	CREB1	O75676	RPS6KA4	S143	D140A	140	Missense	distal	-3	no	1.838	2.492	EPSD	ICGC;COSMIC	2.457	Gain
AGC_RSK_MSK_RPS6KA4_ST	P54253	ATXN1	O75676	RPS6KA4	S25	S26C	26	Missense	proximal	1	no	2.589	2.636	EPSD	ICGC;COSMIC	2.457	Up-regulation
AGC_RSK_MSK_RPS6KA4_ST	P54253	ATXN1	O75676	RPS6KA4	S25	A21T	21	Missense	distal	-4	no	2.589	2.590	EPSD	ICGC;COSMIC	2.457	Up-regulation
AGC_RSK_MSK_RPS6KA4_ST	P54253	ATXN1	O75676	RPS6KA4	S26	S26C	26	Missense	central	0	yes	3.629	0.000	EPSD	ICGC;COSMIC	2.457	Loss
AGC_RSK_MSK_RPS6KA4_ST	P54253	ATXN1	O75676	RPS6KA4	S26	A21T	21	Missense	distal	-5	no	3.629	3.562	EPSD	ICGC;COSMIC	2.457	Down-regulation
AGC_RSK_MSK_RPS6KA4_ST	P54253	ATXN1	O75676	RPS6KA4	S262	R259H	259	Missense	distal	-3	no	3.049	1.608	EPSD	ICGC;COSMIC	2.457	Loss
AGC_RSK_MSK_RPS6KA4_ST	P54253	ATXN1	O75676	RPS6KA4	S262	A265D	265	Missense	distal	3	no	3.049	3.428	EPSD	ICGC	2.457	Up-regulation
AGC_RSK_MSK_RPS6KA4_ST	P54253	ATXN1	O75676	RPS6KA4	S775	T769K	769	Missense	distal	-6	no	4.941	4.942	PhosphoSitePlus	ICGC	2.457	Up-regulation
AGC_RSK_MSK_RPS6KA4_ST	P54253	ATXN1	O75676	RPS6KA4	S775	R770K	770	Missense	distal	-5	no	4.941	5.061	PhosphoSitePlus	ICGC	2.457	Up-regulation
AGC_RSK_MSK_RPS6KA4_ST	P54253	ATXN1	O75676	RPS6KA4	S775	A776E	776	Missense	proximal	1	no	4.941	5.023	PhosphoSitePlus	ICGC	2.457	Up-regulation
AGC_RSK_MSK_RPS6KA4_ST	Q04206	RELA	O75676	RPS6KA4	S203	R198Q	198	Missense	distal	-5	no	3.044	3.178	EPSD	ICGC	2.457	Up-regulation
AGC_RSK_MSK_RPS6KA4_ST	Q04206	RELA	O75676	RPS6KA4	S203	S203Y	203	Missense	central	0	yes	3.044	0.000	EPSD	ICGC	2.457	Loss
AGC_RSK_MSK_RPS6KA4_ST	Q04206	RELA	O75676	RPS6KA4	S276	D277E	277	Missense	proximal	1	no	9.456	9.475	PhosphoSitePlus	ICGC;COSMIC	2.457	Up-regulation
AGC_RSK_MSK_RPS6KA4_ST	Q04206	RELA	O75676	RPS6KA4	S281	D277E	277	Missense	distal	-4	no	3.852	3.855	EPSD	ICGC;COSMIC	2.457	Up-regulation
AGC_RSK_MSK_RPS6KA4_ST	Q04206	RELA	O75676	RPS6KA4	T305	S311G	311	Missense	distal	6	no	2.640	2.821	EPSD	ICGC;COSMIC	2.457	Up-regulation
AGC_RSK_MSK_RPS6KA4_ST	Q04206	RELA	O75676	RPS6KA4	T308	S311G	311	Missense	distal	3	no	2.492	3.155	EPSD	ICGC;COSMIC	2.457	Up-regulation
AGC_RSK_MSK_RPS6KA4_ST	Q04206	RELA	O75676	RPS6KA4	S311	P317H	317	Missense	distal	6	no	3.231	3.161	EPSD	ICGC;COSMIC	2.457	Down-regulation
AGC_RSK_MSK_RPS6KA4_ST	Q04206	RELA	O75676	RPS6KA4	S311	S311G	311	Missense	central	0	yes	3.231	0.000	EPSD	ICGC;COSMIC	2.457	Loss
AGC_RSK_MSK_RPS6KA4_ST	O75676	RPS6KA4	O75676	RPS6KA4	T84	R83C	83	Missense	proximal	-1	no	2.501	2.491	EPSD	ICGC;COSMIC	2.457	Down-regulation
AGC_RSK_MSK_RPS6KA4_ST	O75676	RPS6KA4	O75676	RPS6KA4	T84	R86C	86	Missense	proximal	2	no	2.501	2.464	EPSD	ICGC;COSMIC	2.457	Down-regulation
AGC_RSK_MSK_RPS6KA4_ST	O75676	RPS6KA4	O75676	RPS6KA4	T84	R86H	86	Missense	proximal	2	no	2.501	2.468	EPSD	ICGC;COSMIC	2.457	Down-regulation
AGC_RSK_MSK_RPS6KA4_ST	O75676	RPS6KA4	O75676	RPS6KA4	T178	T178M	178	Missense	central	0	yes	3.288	0.000	EPSD	ICGC;COSMIC	2.457	Loss
AGC_RSK_MSK_RPS6KA4_ST	O75676	RPS6KA4	O75676	RPS6KA4	T178	F180L	180	Missense	proximal	2	no	3.288	3.281	EPSD	ICGC;COSMIC	2.457	Down-regulation
AGC_RSK_MSK_RPS6KA4_ST	O75676	RPS6KA4	O75676	RPS6KA4	T178	G181W	181	Missense	distal	3	no	3.288	2.667	EPSD	ICGC;COSMIC	2.457	Down-regulation
AGC_RSK_MSK_RPS6KA4_ST	O75676	RPS6KA4	O75676	RPS6KA4	S196	R193W	193	Missense	distal	-3	no	8.480	7.158	PhosphoSitePlus	ICGC;COSMIC	2.457	Down-regulation
AGC_RSK_MSK_RPS6KA4_ST	O75676	RPS6KA4	O75676	RPS6KA4	S196	G199V	199	Missense	distal	3	no	8.480	7.641	PhosphoSitePlus	ICGC	2.457	Down-regulation
AGC_RSK_MSK_RPS6KA4_ST	O75676	RPS6KA4	O75676	RPS6KA4	S196	R193Q	193	Missense	distal	-3	no	8.480	6.976	PhosphoSitePlus	ICGC;COSMIC;GDSC;CCLE	2.457	Down-regulation
AGC_RSK_MSK_RPS6KA4_ST	O75676	RPS6KA4	O75676	RPS6KA4	S433	R431C	431	Missense	proximal	-2	no	3.104	0.967	EPSD	ICGC;COSMIC	2.457	Loss
AGC_RSK_MSK_RPS6KA4_ST	O75676	RPS6KA4	O75676	RPS6KA4	S433	S433R	433	Missense	central	0	yes	3.104	0.000	EPSD	ICGC;COSMIC	2.457	Loss
AGC_RSK_MSK_RPS6KA4_ST	O75676	RPS6KA4	O75676	RPS6KA4	S634	R632H	632	Missense	proximal	-2	no	4.360	2.142	EPSD	ICGC;COSMIC	2.457	Loss
AGC_RSK_MSK_RPS6KA4_ST	O75676	RPS6KA4	O75676	RPS6KA4	S671	G670D	670	Missense	proximal	-1	no	3.640	3.656	EPSD	ICGC;COSMIC	2.457	Up-regulation
AGC_RSK_MSK_RPS6KA4_ST	O75676	RPS6KA4	O75676	RPS6KA4	S682	D689N	689	Missense	distal	7	no	3.084	3.091	EPSD	ICGC;COSMIC	2.457	Up-regulation
TKL_MLK_ILK_ILK_ST	O14950	MYL12B	Q13418	ILK	T19	T19A	19	Missense	central	0	yes	21.935	0.000	EPSD;PhosphoSitePlus	ICGC;COSMIC	15.108	Loss
TKL_MLK_ILK_ILK_ST	O14950	MYL12B	Q13418	ILK	S20	T19A	19	Missense	proximal	-1	no	20.941	21.093	PhosphoSitePlus;EPSD	ICGC;COSMIC	15.108	Up-regulation
TKL_MLK_ILK_ILK_ST	O14950	MYL12B	Q13418	ILK	T135	M130I	130	Missense	distal	-5	no	15.716	15.354	EPSD	ICGC	15.108	Down-regulation
TKL_MLK_ILK_ILK_ST	O14950	MYL12B	Q13418	ILK	T135	T129I	129	Missense	distal	-6	no	15.716	15.880	EPSD	ICGC;COSMIC	15.108	Up-regulation
TKL_MLK_ILK_ILK_ST	P31749	AKT1	Q13418	ILK	T34	K30N	30	Missense	distal	-4	no	18.369	17.993	EPSD	ICGC;COSMIC	15.108	Down-regulation
TKL_MLK_ILK_ILK_ST	P31749	AKT1	Q13418	ILK	T65	Q59L	59	Missense	distal	-6	no	15.698	15.275	EPSD	ICGC;COSMIC	15.108	Down-regulation
TKL_MLK_ILK_ILK_ST	P31749	AKT1	Q13418	ILK	T65	A58V	58	Missense	distal	-7	no	15.698	15.695	EPSD	ICGC;COSMIC	15.108	Down-regulation
TKL_MLK_ILK_ILK_ST	P31749	AKT1	Q13418	ILK	T65	T65K	65	Missense	central	0	yes	15.698	0.000	EPSD	ICGC	15.108	Loss
TKL_MLK_ILK_ILK_ST	P31749	AKT1	Q13418	ILK	T65	Q61K	61	Missense	distal	-4	no	15.698	15.071	EPSD	ICGC	15.108	Loss
TKL_MLK_ILK_ILK_ST	P31749	AKT1	Q13418	ILK	S246	V244A	244	Missense	proximal	-2	no	6.962	16.986	EPSD	ICGC	15.108	Gain
TKL_MLK_ILK_ILK_ST	Q96A00	PPP1R14A	Q13418	ILK	T38	Q31K	31	Missense	distal	-7	no	44.965	44.962	PhosphoSitePlus	ICGC	15.108	Down-regulation
TKL_MLK_ILK_ILK_ST	Q96A00	PPP1R14A	Q13418	ILK	T38	H34Y	34	Missense	distal	-4	no	44.965	45.231	PhosphoSitePlus	ICGC;COSMIC	15.108	Up-regulation
TKL_MLK_ILK_ILK_ST	Q96A00	PPP1R14A	Q13418	ILK	T38	H34Q	34	Missense	distal	-4	no	44.965	46.128	PhosphoSitePlus	ICGC	15.108	Up-regulation
TKL_MLK_ILK_ILK_ST	Q96A00	PPP1R14A	Q13418	ILK	T38	A35T	35	Missense	distal	-3	no	44.965	44.928	PhosphoSitePlus	ICGC;COSMIC	15.108	Down-regulation
TKL_MLK_ILK_ILK_ST	Q8TAE6	PPP1R14C	Q13418	ILK	S47	P49L	49	Missense	proximal	2	no	16.626	16.389	EPSD	ICGC;COSMIC	15.108	Down-regulation
TKL_MLK_ILK_ILK_ST	Q8TAE6	PPP1R14C	Q13418	ILK	S47	S43Y	43	Missense	distal	-4	no	16.626	17.209	EPSD	ICGC;COSMIC	15.108	Up-regulation
TKL_MLK_ILK_ILK_ST	Q8TAE6	PPP1R14C	Q13418	ILK	T73	K75R	75	Missense	proximal	2	no	43.142	42.898	PhosphoSitePlus	ICGC	15.108	Down-regulation
TKL_MLK_ILK_ILK_ST	Q8TAE6	PPP1R14C	Q13418	ILK	T73	G70V	70	Missense	distal	-3	no	43.142	44.086	PhosphoSitePlus	ICGC	15.108	Up-regulation
TKL_MLK_ILK_ILK_ST	Q8TAE6	PPP1R14C	Q13418	ILK	T73	V74A	74	Missense	proximal	1	no	43.142	42.877	PhosphoSitePlus	ICGC	15.108	Down-regulation
TKL_MLK_ILK_ILK_ST	E9PAV3	NACA	Q13418	ILK	T853	S860P	860	Missense	distal	7	no	16.734	16.052	EPSD	ICGC;COSMIC	15.108	Down-regulation
TKL_MLK_ILK_ILK_ST	E9PAV3	NACA	Q13418	ILK	T853	P859T	859	Missense	distal	6	no	16.734	17.294	EPSD	ICGC	15.108	Up-regulation
TKL_MLK_ILK_ILK_ST	E9PAV3	NACA	Q13418	ILK	T853	S846Y	846	Missense	distal	-7	no	16.734	16.741	EPSD	ICGC;COSMIC	15.108	Up-regulation
TKL_MLK_ILK_ILK_ST	E9PAV3	NACA	Q13418	ILK	T853	P858S	858	Missense	distal	5	no	16.734	16.690	EPSD	ICGC;COSMIC	15.108	Down-regulation
TKL_MLK_ILK_ILK_ST	E9PAV3	NACA	Q13418	ILK	T853	T853M	853	Missense	central	0	yes	16.734	0.000	EPSD	ICGC;COSMIC	15.108	Loss
TKL_MLK_ILK_ILK_ST	E9PAV3	NACA	Q13418	ILK	T853	T852M	852	Missense	proximal	-1	no	16.734	16.361	EPSD	ICGC;COSMIC	15.108	Down-regulation
TKL_MLK_ILK_ILK_ST	E9PAV3	NACA	Q13418	ILK	T853	P858L	858	Missense	distal	5	no	16.734	17.738	EPSD	ICGC	15.108	Up-regulation
TKL_MLK_ILK_ILK_ST	E9PAV3	NACA	Q13418	ILK	S868	S868P	868	Missense	central	0	yes	15.982	0.000	EPSD	ICGC	15.108	Loss
TKL_MLK_ILK_ILK_ST	E9PAV3	NACA	Q13418	ILK	S868	S874P	874	Missense	distal	6	no	15.982	15.564	EPSD	ICGC	15.108	Down-regulation
TKL_MLK_ILK_ILK_ST	E9PAV3	NACA	Q13418	ILK	S868	P867S	867	Missense	proximal	-1	no	15.982	15.480	EPSD	ICGC	15.108	Down-regulation
TKL_MLK_ILK_ILK_ST	E9PAV3	NACA	Q13418	ILK	S868	S874F	874	Missense	distal	6	no	15.982	16.407	EPSD	ICGC;COSMIC	15.108	Up-regulation
TKL_MLK_ILK_ILK_ST	E9PAV3	NACA	Q13418	ILK	T1015	P1016H	1016	Missense	proximal	1	no	18.747	18.938	EPSD	ICGC;COSMIC	15.108	Up-regulation
TKL_MLK_ILK_ILK_ST	E9PAV3	NACA	Q13418	ILK	T1339	P1336S	1336	Missense	distal	-3	no	16.295	15.890	EPSD	ICGC;COSMIC	15.108	Down-regulation
TKL_MLK_ILK_ILK_ST	E9PAV3	NACA	Q13418	ILK	T1339	S1342F	1342	Missense	distal	3	no	16.295	17.764	EPSD	ICGC	15.108	Up-regulation
TKL_MLK_ILK_ILK_ST	E9PAV3	NACA	Q13418	ILK	T1339	P1335L	1335	Missense	distal	-4	no	16.295	15.146	EPSD	ICGC;COSMIC	15.108	Down-regulation
TKL_MLK_ILK_ILK_ST	E9PAV3	NACA	Q13418	ILK	T1339	A1337V	1337	Missense	proximal	-2	no	16.295	6.270	EPSD	ICGC;COSMIC	15.108	Loss
TKL_MLK_ILK_ILK_ST	E9PAV3	NACA	Q13418	ILK	T1339	P1336A	1336	Missense	distal	-3	no	16.295	16.011	EPSD	ICGC;COSMIC	15.108	Down-regulation
TKL_MLK_ILK_ILK_ST	E9PAV3	NACA	Q13418	ILK	T1519	P1517A	1517	Missense	proximal	-2	no	7.144	15.727	EPSD	ICGC;COSMIC	15.108	Gain
TKL_MLK_ILK_ILK_ST	E9PAV3	NACA	Q13418	ILK	S1581	S1576F	1576	Missense	distal	-5	no	16.375	16.560	EPSD	ICGC;COSMIC	15.108	Up-regulation
TKL_MLK_ILK_ILK_ST	E9PAV3	NACA	Q13418	ILK	T1586	A1593D	1593	Missense	distal	7	no	15.253	16.785	EPSD	ICGC	15.108	Up-regulation
TKL_MLK_ILK_ILK_ST	E9PAV3	NACA	Q13418	ILK	T1586	G1592W	1592	Missense	distal	6	no	15.253	14.477	EPSD	ICGC;COSMIC	15.108	Loss
TKL_MLK_ILK_ILK_ST	E9PAV3	NACA	Q13418	ILK	T1606	E1612K	1612	Missense	distal	6	no	16.554	16.866	EPSD	ICGC;COSMIC	15.108	Up-regulation
TKL_MLK_ILK_ILK_ST	E9PAV3	NACA	Q13418	ILK	T1606	S1609Y	1609	Missense	distal	3	no	16.554	21.040	EPSD	ICGC	15.108	Up-regulation
TKL_MLK_ILK_ILK_ST	E9PAV3	NACA	Q13418	ILK	T1636	A1632D	1632	Missense	distal	-4	no	16.225	17.256	EPSD	ICGC	15.108	Up-regulation
TKL_MLK_ILK_ILK_ST	E9PAV3	NACA	Q13418	ILK	T1636	P1640S	1640	Missense	distal	4	no	16.225	16.348	EPSD	ICGC	15.108	Up-regulation
TKL_MLK_ILK_ILK_ST	E9PAV3	NACA	Q13418	ILK	T1636	P1637L	1637	Missense	proximal	1	no	16.225	16.217	EPSD	ICGC	15.108	Down-regulation
TKL_MLK_ILK_ILK_ST	E9PAV3	NACA	Q13418	ILK	S1713	I1716V	1716	Missense	distal	3	no	13.943	15.760	EPSD	ICGC;CCLE	15.108	Gain
TKL_MLK_ILK_ILK_ST	Q96C90	PPP1R14B	Q13418	ILK	T57	R52S	52	Missense	distal	-5	no	41.632	41.343	PhosphoSitePlus	ICGC	15.108	Down-regulation
CK1_VRK_VRK1_ST	P38432	COIL	Q99986	VRK1	S129	H132N	132	Missense	distal	3	no	0.325	0.317	EPSD	ICGC	0.296	Down-regulation
CK1_VRK_VRK1_ST	P38432	COIL	Q99986	VRK1	S129	S135N	135	Missense	distal	6	no	0.325	0.303	EPSD	ICGC;COSMIC	0.296	Down-regulation
CK1_VRK_VRK1_ST	P38432	COIL	Q99986	VRK1	S129	P124T	124	Missense	distal	-5	no	0.325	0.326	EPSD	ICGC;COSMIC	0.296	Up-regulation
CK1_VRK_VRK1_ST	P38432	COIL	Q99986	VRK1	S184	E178K	178	Missense	distal	-6	no	0.498	0.504	PhosphoSitePlus	ICGC;COSMIC	0.296	Up-regulation
CK1_VRK_VRK1_ST	P38432	COIL	Q99986	VRK1	S184	N177K	177	Missense	distal	-7	no	0.498	0.502	PhosphoSitePlus	ICGC	0.296	Up-regulation
CK1_VRK_VRK1_ST	P38432	COIL	Q99986	VRK1	S184	A180D	180	Missense	distal	-4	no	0.498	0.479	PhosphoSitePlus	ICGC	0.296	Down-regulation
CK1_VRK_VRK1_ST	P38432	COIL	Q99986	VRK1	S184	E179A	179	Missense	distal	-5	no	0.498	0.522	PhosphoSitePlus	ICGC	0.296	Up-regulation
CK1_VRK_VRK1_ST	P38432	COIL	Q99986	VRK1	S316	S319C	319	Missense	distal	3	no	0.297	0.300	EPSD	ICGC;COSMIC	0.296	Up-regulation
CK1_VRK_VRK1_ST	P38432	COIL	Q99986	VRK1	S317	S319C	319	Missense	proximal	2	no	0.331	0.309	EPSD	ICGC;COSMIC	0.296	Down-regulation
CK1_VRK_VRK1_ST	P38432	COIL	Q99986	VRK1	S486	T485K	485	Missense	proximal	-1	no	0.327	0.322	EPSD	ICGC	0.296	Down-regulation
CK1_VRK_VRK1_ST	P38432	COIL	Q99986	VRK1	S486	L482F	482	Missense	distal	-4	no	0.327	0.283	EPSD	ICGC;COSMIC	0.296	Loss
CK1_VRK_VRK1_ST	P38432	COIL	Q99986	VRK1	S487	T485K	485	Missense	proximal	-2	no	0.339	0.332	EPSD	ICGC	0.296	Down-regulation
CK1_VRK_VRK1_ST	P05412	JUN	Q99986	VRK1	S63	K70T	70	Missense	distal	7	no	0.433	0.425	EPSD;PhosphoSitePlus	ICGC;COSMIC	0.296	Down-regulation
CK1_VRK_VRK1_ST	P05412	JUN	Q99986	VRK1	S73	A72E	72	Missense	proximal	-1	no	0.503	0.501	PhosphoSitePlus;EPSD	ICGC;COSMIC	0.296	Down-regulation
CK1_VRK_VRK1_ST	P15336	ATF2	Q99986	VRK1	S136	E130K	130	Missense	distal	-6	no	0.374	0.379	EPSD	ICGC;COSMIC	0.296	Up-regulation
CK1_VRK_VRK1_ST	P04637	TP53	Q99986	VRK1	T18	E11K	11	Missense	distal	-7	no	0.435	0.429	PhosphoSitePlus	ICGC;COSMIC	0.296	Down-regulation
CK1_VRK_VRK1_ST	P04637	TP53	Q99986	VRK1	T18	W23C	23	Missense	distal	5	no	0.435	0.429	PhosphoSitePlus	ICGC;COSMIC	0.296	Down-regulation
CK1_VRK_VRK1_ST	P04637	TP53	Q99986	VRK1	S149	P142H	142	Missense	distal	-7	no	0.377	0.374	EPSD	ICGC;COSMIC	0.296	Down-regulation
CK1_VRK_VRK1_ST	P04637	TP53	Q99986	VRK1	S149	R156L	156	Missense	distal	7	no	0.377	0.386	EPSD	ICGC;COSMIC	0.296	Up-regulation
CK1_VRK_VRK1_ST	P04637	TP53	Q99986	VRK1	S149	L145Q	145	Missense	distal	-4	no	0.377	0.337	EPSD	ICGC;COSMIC	0.296	Down-regulation
CK1_VRK_VRK1_ST	P04637	TP53	Q99986	VRK1	S149	P152R	152	Missense	distal	3	no	0.377	0.385	EPSD	ICGC;COSMIC	0.296	Up-regulation
CK1_VRK_VRK1_ST	P04637	TP53	Q99986	VRK1	S149	G154S	154	Missense	distal	5	no	0.377	0.376	EPSD	ICGC;COSMIC	0.296	Down-regulation
CK1_VRK_VRK1_ST	P04637	TP53	Q99986	VRK1	S149	P151F	151	Missense	proximal	2	no	0.377	0.379	EPSD	ICGC;COSMIC	0.296	Up-regulation
CK1_VRK_VRK1_ST	P04637	TP53	Q99986	VRK1	S149	V147G	147	Missense	proximal	-2	no	0.377	0.376	EPSD	ICGC;COSMIC;GDSC;CCLE	0.296	Down-regulation
CK1_VRK_VRK1_ST	Q99986	VRK1	Q99986	VRK1	T305	L309I	309	Missense	distal	4	no	0.338	0.318	EPSD	ICGC;COSMIC	0.296	Down-regulation
CK1_VRK_VRK1_ST	Q99986	VRK1	Q99986	VRK1	T305	A300S	300	Missense	distal	-5	no	0.338	0.305	EPSD	ICGC;COSMIC	0.296	Down-regulation
CK1_VRK_VRK1_ST	Q99986	VRK1	Q99986	VRK1	T305	V306L	306	Missense	proximal	1	no	0.338	0.334	EPSD	ICGC	0.296	Down-regulation
AGC_PKC_PKCi_PRKCI_ST	Q7KZI7	MARK2	P41743	PRKCI	T20	T16A	16	Missense	distal	-4	no	6.235	6.407	EPSD	ICGC	6.376	Gain
AGC_PKC_PKCi_PRKCI_ST	Q7KZI7	MARK2	P41743	PRKCI	T20	L21F	21	Missense	proximal	1	no	6.235	8.330	EPSD	ICGC;COSMIC	6.376	Gain
AGC_PKC_PKCi_PRKCI_ST	Q7KZI7	MARK2	P41743	PRKCI	S30	S32F	32	Missense	proximal	2	no	8.250	6.896	EPSD	ICGC;COSMIC	6.376	Down-regulation
AGC_PKC_PKCi_PRKCI_ST	Q7KZI7	MARK2	P41743	PRKCI	S30	R36Q	36	Missense	distal	6	no	8.250	8.164	EPSD	ICGC	6.376	Down-regulation
AGC_PKC_PKCi_PRKCI_ST	Q7KZI7	MARK2	P41743	PRKCI	T467	L461F	461	Missense	distal	-6	no	8.882	8.620	EPSD	ICGC	6.376	Down-regulation
AGC_PKC_PKCi_PRKCI_ST	Q7KZI7	MARK2	P41743	PRKCI	S759	L755R	755	Missense	distal	-4	no	7.793	8.052	EPSD	ICGC;COSMIC	6.376	Up-regulation
AGC_PKC_PKCi_PRKCI_ST	Q4VCS5	AMOT	P41743	PRKCI	S328	Q324K	324	Missense	distal	-4	no	6.565	6.509	EPSD	ICGC;COSMIC	6.376	Down-regulation
AGC_PKC_PKCi_PRKCI_ST	Q4VCS5	AMOT	P41743	PRKCI	S328	A334T	334	Missense	distal	6	no	6.565	6.589	EPSD	ICGC	6.376	Up-regulation
AGC_PKC_PKCi_PRKCI_ST	Q4VCS5	AMOT	P41743	PRKCI	S332	A334T	334	Missense	proximal	2	no	5.904	6.526	EPSD	ICGC	6.376	Gain
AGC_PKC_PKCi_PRKCI_ST	Q4VCS5	AMOT	P41743	PRKCI	T536	A542T	542	Missense	distal	6	no	7.335	7.360	PhosphoSitePlus;EPSD	ICGC	6.376	Up-regulation
AGC_PKC_PKCi_PRKCI_ST	Q4VCS5	AMOT	P41743	PRKCI	S538	A542T	542	Missense	distal	4	no	8.288	8.372	EPSD;PhosphoSitePlus	ICGC	6.376	Up-regulation
AGC_PKC_PKCi_PRKCI_ST	Q4VCS5	AMOT	P41743	PRKCI	T750	M744K	744	Missense	distal	-6	no	9.318	9.310	EPSD;PhosphoSitePlus	ICGC;COSMIC	6.376	Down-regulation
AGC_PKC_PKCi_PRKCI_ST	Q4VCS5	AMOT	P41743	PRKCI	S855	S852L	852	Missense	distal	-3	no	6.852	5.016	EPSD	ICGC	6.376	Loss
AGC_PKC_PKCi_PRKCI_ST	P10636	MAPT	P41743	PRKCI	T123	D116E	116	Missense	distal	-7	no	8.172	7.744	EPSD	ICGC;COSMIC	6.376	Down-regulation
AGC_PKC_PKCi_PRKCI_ST	P10636	MAPT	P41743	PRKCI	T123	E127K	127	Missense	distal	4	no	8.172	8.292	EPSD	ICGC	6.376	Up-regulation
AGC_PKC_PKCi_PRKCI_ST	P10636	MAPT	P41743	PRKCI	S214	G208C	208	Missense	distal	-6	no	10.639	10.856	EPSD	ICGC;COSMIC	6.376	Up-regulation
AGC_PKC_PKCi_PRKCI_ST	P10636	MAPT	P41743	PRKCI	S214	R211S	211	Missense	distal	-3	no	10.639	9.582	EPSD	ICGC;COSMIC	6.376	Down-regulation
AGC_PKC_PKCi_PRKCI_ST	P10636	MAPT	P41743	PRKCI	S214	G213E	213	Missense	proximal	-1	no	10.639	10.858	EPSD	ICGC;COSMIC	6.376	Up-regulation
AGC_PKC_PKCi_PRKCI_ST	P10636	MAPT	P41743	PRKCI	S341	T346I	346	Missense	distal	5	no	6.535	6.300	EPSD	ICGC;COSMIC	6.376	Loss
AGC_PKC_PKCi_PRKCI_ST	P10636	MAPT	P41743	PRKCI	S341	A337V	337	Missense	distal	-4	no	6.535	6.176	EPSD	ICGC	6.376	Loss
AGC_PKC_PKCi_PRKCI_ST	P10636	MAPT	P41743	PRKCI	S341	D345E	345	Missense	distal	4	no	6.535	6.253	EPSD	ICGC;COSMIC	6.376	Loss
AGC_PKC_PKCi_PRKCI_ST	P10636	MAPT	P41743	PRKCI	S447	Y441H	441	Missense	distal	-6	no	6.735	6.219	EPSD	ICGC;COSMIC	6.376	Loss
AGC_PKC_PKCi_PRKCI_ST	P10636	MAPT	P41743	PRKCI	S516	G521R	521	Missense	distal	5	no	5.993	6.484	EPSD	ICGC;COSMIC	6.376	Gain
AGC_PKC_PKCi_PRKCI_ST	Q13464	ROCK1	P41743	PRKCI	S633	E636D	636	Missense	distal	3	no	12.099	12.358	EPSD	ICGC;COSMIC	6.376	Up-regulation
AGC_PKC_PKCi_PRKCI_ST	Q13464	ROCK1	P41743	PRKCI	S633	K639N	639	Missense	distal	6	no	12.099	11.983	EPSD	ICGC;COSMIC	6.376	Down-regulation
AGC_PKC_PKCi_PRKCI_ST	Q13464	ROCK1	P41743	PRKCI	T887	L881V	881	Missense	distal	-6	no	8.702	8.530	EPSD	ICGC	6.376	Down-regulation
AGC_PKC_PKCi_PRKCI_ST	Q13464	ROCK1	P41743	PRKCI	T887	L894I	894	Missense	distal	7	no	8.702	8.688	EPSD	ICGC	6.376	Down-regulation
AGC_PKC_PKCi_PRKCI_ST	Q13464	ROCK1	P41743	PRKCI	T890	L894I	894	Missense	distal	4	no	7.158	7.267	EPSD	ICGC	6.376	Up-regulation
AGC_PKC_PKCi_PRKCI_ST	Q13464	ROCK1	P41743	PRKCI	T1024	L1027W	1027	Missense	distal	3	no	8.876	9.194	EPSD;PhosphoSitePlus	ICGC;COSMIC	6.376	Up-regulation
AGC_PKC_PKCi_PRKCI_ST	Q13464	ROCK1	P41743	PRKCI	T1180	T1180N	1180	Missense	central	0	yes	9.370	0.000	EPSD	ICGC;COSMIC	6.376	Loss
AGC_PKC_PKCi_PRKCI_ST	Q13464	ROCK1	P41743	PRKCI	T1180	P1178H	1178	Missense	proximal	-2	no	9.370	9.708	EPSD	ICGC	6.376	Up-regulation
AGC_PKC_PKCi_PRKCI_ST	Q13464	ROCK1	P41743	PRKCI	T1180	R1177T	1177	Missense	distal	-3	no	9.370	8.121	EPSD	ICGC	6.376	Down-regulation
AGC_PKC_PKCi_PRKCI_ST	Q13464	ROCK1	P41743	PRKCI	T1331	R1326S	1326	Missense	distal	-5	no	6.613	4.124	EPSD	ICGC;COSMIC	6.376	Loss
AGC_PKC_PKCi_PRKCI_ST	Q13464	ROCK1	P41743	PRKCI	T1331	R1326C	1326	Missense	distal	-5	no	6.613	1.583	EPSD	ICGC;COSMIC	6.376	Loss
AGC_PKC_PKCi_PRKCI_ST	Q13464	ROCK1	P41743	PRKCI	T1331	R1335I	1335	Missense	distal	4	no	6.613	7.286	EPSD	ICGC	6.376	Up-regulation
AGC_PKC_PKCi_PRKCI_ST	Q13464	ROCK1	P41743	PRKCI	S1333	N1339K	1339	Missense	distal	6	no	6.478	6.595	EPSD;PhosphoSitePlus	ICGC;COSMIC	6.376	Up-regulation
AGC_PKC_PKCi_PRKCI_ST	Q13464	ROCK1	P41743	PRKCI	S1333	R1326S	1326	Missense	distal	-7	no	6.478	6.848	EPSD;PhosphoSitePlus	ICGC;COSMIC	6.376	Up-regulation
AGC_PKC_PKCi_PRKCI_ST	Q13464	ROCK1	P41743	PRKCI	S1333	R1326C	1326	Missense	distal	-7	no	6.478	8.056	EPSD;PhosphoSitePlus	ICGC;COSMIC	6.376	Up-regulation
AGC_PKC_PKCi_PRKCI_ST	Q13464	ROCK1	P41743	PRKCI	S1333	R1335I	1335	Missense	proximal	2	no	6.478	3.871	EPSD;PhosphoSitePlus	ICGC	6.376	Loss
AGC_PKC_PKCi_PRKCI_ST	Q13464	ROCK1	P41743	PRKCI	S1341	N1339K	1339	Missense	proximal	-2	no	8.401	8.806	EPSD;PhosphoSitePlus	ICGC;COSMIC	6.376	Up-regulation
AGC_PKC_PKCi_PRKCI_ST	Q13464	ROCK1	P41743	PRKCI	S1341	R1335I	1335	Missense	distal	-6	no	8.401	9.442	EPSD;PhosphoSitePlus	ICGC	6.376	Up-regulation
AGC_PKC_PKCi_PRKCI_ST	Q92934	BAD	P41743	PRKCI	S17	S15Y	15	Missense	proximal	-2	no	6.885	6.783	EPSD	ICGC	6.376	Down-regulation
AGC_PKC_PKCi_PRKCI_ST	Q92934	BAD	P41743	PRKCI	S75	R72S	72	Missense	distal	-3	no	9.961	8.905	PhosphoSitePlus;EPSD	ICGC	6.376	Down-regulation
AGC_PKC_PKCi_PRKCI_ST	Q92934	BAD	P41743	PRKCI	S75	T80K	80	Missense	distal	5	no	9.961	10.248	PhosphoSitePlus;EPSD	ICGC	6.376	Up-regulation
AGC_PKC_PKCi_PRKCI_ST	Q92934	BAD	P41743	PRKCI	S75	S74G	74	Missense	proximal	-1	no	9.961	9.748	PhosphoSitePlus;EPSD	ICGC;COSMIC	6.376	Down-regulation
AGC_PKC_PKCi_PRKCI_ST	Q92934	BAD	P41743	PRKCI	S99	S99L	99	Missense	central	0	yes	9.931	0.000	EPSD;PhosphoSitePlus	ICGC	6.376	Loss
AGC_PKC_PKCi_PRKCI_ST	Q92934	BAD	P41743	PRKCI	S99	R94W	94	Missense	distal	-5	no	9.931	5.288	EPSD;PhosphoSitePlus	ICGC	6.376	Loss
AGC_PKC_PKCi_PRKCI_ST	Q92934	BAD	P41743	PRKCI	S118	R112S	112	Missense	distal	-6	no	7.851	8.037	EPSD;PhosphoSitePlus	ICGC	6.376	Up-regulation
AGC_PKC_PKCi_PRKCI_ST	P15311	EZR	P41743	PRKCI	S249	F255L	255	Missense	distal	6	no	9.309	9.330	EPSD	ICGC;COSMIC	6.376	Up-regulation
AGC_PKC_PKCi_PRKCI_ST	P15311	EZR	P41743	PRKCI	S249	D252H	252	Missense	distal	3	no	9.309	9.209	EPSD	ICGC	6.376	Down-regulation
AGC_PKC_PKCi_PRKCI_ST	P15311	EZR	P41743	PRKCI	T299	P297H	297	Missense	proximal	-2	no	6.868	7.205	EPSD	ICGC	6.376	Up-regulation
AGC_PKC_PKCi_PRKCI_ST	P15311	EZR	P41743	PRKCI	T299	I300T	300	Missense	proximal	1	no	6.868	5.831	EPSD	ICGC	6.376	Loss
AGC_PKC_PKCi_PRKCI_ST	P15311	EZR	P41743	PRKCI	T299	R293C	293	Missense	distal	-6	no	6.868	8.269	EPSD	ICGC;COSMIC;CCLE	6.376	Up-regulation
AGC_PKC_PKCi_PRKCI_ST	P15311	EZR	P41743	PRKCI	T358	K357T	357	Missense	proximal	-1	no	8.091	8.042	EPSD	ICGC;COSMIC	6.376	Down-regulation
AGC_PKC_PKCi_PRKCI_ST	P15311	EZR	P41743	PRKCI	T358	A361E	361	Missense	distal	3	no	8.091	7.998	EPSD	ICGC	6.376	Down-regulation
AGC_PKC_PKCi_PRKCI_ST	P15311	EZR	P41743	PRKCI	T567	T567M	567	Missense	central	0	yes	11.891	0.000	PhosphoSitePlus	ICGC;COSMIC	6.376	Loss
AGC_PKC_PKCi_PRKCI_ST	P15311	EZR	P41743	PRKCI	T567	Q573K	573	Missense	distal	6	no	11.891	11.831	PhosphoSitePlus	ICGC	6.376	Down-regulation
AGC_PKC_PKCi_PRKCI_ST	P15311	EZR	P41743	PRKCI	T576	R579H	579	Missense	distal	3	no	6.044	6.439	EPSD	ICGC;COSMIC	6.376	Gain
AGC_PKC_PKCi_PRKCI_ST	Q15910	EZH2	P41743	PRKCI	T345	P350S	350	Missense	distal	5	no	10.081	10.060	EPSD;PhosphoSitePlus	ICGC;COSMIC	6.376	Down-regulation
AGC_PKC_PKCi_PRKCI_ST	Q15910	EZH2	P41743	PRKCI	T345	R342P	342	Missense	distal	-3	no	10.081	6.755	EPSD;PhosphoSitePlus	ICGC;COSMIC	6.376	Down-regulation
AGC_PKC_PKCi_PRKCI_ST	Q15910	EZH2	P41743	PRKCI	T345	R349H	349	Missense	distal	4	no	10.081	10.374	EPSD;PhosphoSitePlus	ICGC;COSMIC	6.376	Up-regulation
AGC_PKC_PKCi_PRKCI_ST	Q15910	EZH2	P41743	PRKCI	S690	R685H	685	Missense	distal	-5	no	11.100	9.172	EPSD;PhosphoSitePlus	ICGC;COSMIC	6.376	Down-regulation
AGC_PKC_PKCi_PRKCI_ST	Q15910	EZH2	P41743	PRKCI	S690	S690L	690	Missense	central	0	yes	11.100	0.000	EPSD;PhosphoSitePlus	ICGC;COSMIC	6.376	Loss
AGC_PKC_PKCi_PRKCI_ST	Q15910	EZH2	P41743	PRKCI	S690	N688K	688	Missense	proximal	-2	no	11.100	11.505	EPSD;PhosphoSitePlus	ICGC;COSMIC	6.376	Up-regulation
AGC_PKC_PKCi_PRKCI_ST	Q15910	EZH2	P41743	PRKCI	S690	A697E	697	Missense	distal	7	no	11.100	11.080	EPSD;PhosphoSitePlus	ICGC	6.376	Down-regulation
AGC_PKC_PKCi_PRKCI_ST	Q15910	EZH2	P41743	PRKCI	S690	I684S	684	Missense	distal	-6	no	11.100	10.246	EPSD;PhosphoSitePlus	ICGC;COSMIC	6.376	Down-regulation
AGC_PKC_PKCi_PRKCI_ST	Q15910	EZH2	P41743	PRKCI	S690	R685G	685	Missense	distal	-5	no	11.100	7.644	EPSD;PhosphoSitePlus	ICGC;COSMIC	6.376	Down-regulation
AGC_PKC_PKCi_PRKCI_ST	Q15910	EZH2	P41743	PRKCI	S690	K683E	683	Missense	distal	-7	no	11.100	11.081	EPSD;PhosphoSitePlus	ICGC	6.376	Down-regulation
AGC_PKC_PKCi_PRKCI_ST	Q15910	EZH2	P41743	PRKCI	S690	K683T	683	Missense	distal	-7	no	11.100	10.977	EPSD;PhosphoSitePlus	ICGC	6.376	Down-regulation
AGC_PKC_PKCi_PRKCI_ST	Q15910	EZH2	P41743	PRKCI	S690	A687V	687	Missense	distal	-3	no	11.100	9.025	EPSD;PhosphoSitePlus	ICGC;COSMIC;CCLE	6.376	Down-regulation
AGC_PKC_PKCi_PRKCI_ST	P08047	SP1	P41743	PRKCI	S7	S7P	7	Missense	central	0	yes	7.903	0.000	EPSD	ICGC;COSMIC	6.376	Loss
AGC_PKC_PKCi_PRKCI_ST	P08047	SP1	P41743	PRKCI	S7	S7Y	7	Missense	central	0	yes	7.903	0.000	EPSD	ICGC;COSMIC	6.376	Loss
AGC_PKC_PKCi_PRKCI_ST	P08047	SP1	P41743	PRKCI	S7	M11I	11	Missense	distal	4	no	7.903	8.250	EPSD	ICGC	6.376	Up-regulation
AGC_PKC_PKCi_PRKCI_ST	P08047	SP1	P41743	PRKCI	S7	M8I	8	Missense	proximal	1	no	7.903	6.799	EPSD	ICGC	6.376	Down-regulation
AGC_PKC_PKCi_PRKCI_ST	P08047	SP1	P41743	PRKCI	S59	S56A	56	Missense	distal	-3	no	12.403	11.874	PhosphoSitePlus	ICGC;COSMIC	6.376	Down-regulation
AGC_PKC_PKCi_PRKCI_ST	P08047	SP1	P41743	PRKCI	S101	N105S	105	Missense	distal	4	no	10.136	9.881	EPSD	ICGC;COSMIC	6.376	Down-regulation
AGC_PKC_PKCi_PRKCI_ST	P08047	SP1	P41743	PRKCI	S101	G103D	103	Missense	proximal	2	no	10.136	9.928	EPSD	ICGC;COSMIC	6.376	Down-regulation
AGC_PKC_PKCi_PRKCI_ST	Q14247	CTTN	P41743	PRKCI	S109	V115L	115	Missense	distal	6	no	7.813	7.944	EPSD	ICGC	6.376	Up-regulation
AGC_PKC_PKCi_PRKCI_ST	Q14247	CTTN	P41743	PRKCI	S109	Q114H	114	Missense	distal	5	no	7.813	7.700	EPSD	ICGC	6.376	Down-regulation
AGC_PKC_PKCi_PRKCI_ST	Q14247	CTTN	P41743	PRKCI	S113	V115L	115	Missense	proximal	2	no	6.589	7.236	EPSD	ICGC	6.376	Up-regulation
AGC_PKC_PKCi_PRKCI_ST	Q14247	CTTN	P41743	PRKCI	S113	G120C	120	Missense	distal	7	no	6.589	6.452	EPSD	ICGC	6.376	Down-regulation
AGC_PKC_PKCi_PRKCI_ST	Q14247	CTTN	P41743	PRKCI	S113	Q114H	114	Missense	proximal	1	no	6.589	5.394	EPSD	ICGC	6.376	Loss
AGC_PKC_PKCi_PRKCI_ST	Q14247	CTTN	P41743	PRKCI	T145	K144N	144	Missense	proximal	-1	no	7.911	7.674	EPSD	ICGC	6.376	Down-regulation
AGC_PKC_PKCi_PRKCI_ST	Q14247	CTTN	P41743	PRKCI	S150	K144N	144	Missense	distal	-6	no	11.991	11.812	EPSD	ICGC	6.376	Down-regulation
AGC_PKC_PKCi_PRKCI_ST	Q14247	CTTN	P41743	PRKCI	S187	G180V	180	Missense	distal	-7	no	13.989	13.944	EPSD	ICGC;COSMIC	6.376	Down-regulation
AGC_PKC_PKCi_PRKCI_ST	Q14247	CTTN	P41743	PRKCI	S187	S187P	187	Missense	central	0	yes	13.989	0.000	EPSD	ICGC	6.376	Loss
AGC_PKC_PKCi_PRKCI_ST	Q14247	CTTN	P41743	PRKCI	S192	G196D	196	Missense	distal	4	no	6.786	6.758	EPSD	ICGC;COSMIC	6.376	Down-regulation
AGC_PKC_PKCi_PRKCI_ST	Q14247	CTTN	P41743	PRKCI	S192	S187P	187	Missense	distal	-5	no	6.786	5.597	EPSD	ICGC	6.376	Loss
AGC_PKC_PKCi_PRKCI_ST	Q14247	CTTN	P41743	PRKCI	S192	G197D	197	Missense	distal	5	no	6.786	6.832	EPSD	ICGC;COSMIC	6.376	Up-regulation
AGC_PKC_PKCi_PRKCI_ST	Q14247	CTTN	P41743	PRKCI	S224	G231R	231	Missense	distal	7	no	8.299	8.413	EPSD	ICGC	6.376	Up-regulation
AGC_PKC_PKCi_PRKCI_ST	Q14247	CTTN	P41743	PRKCI	S282	D288N	288	Missense	distal	6	no	6.776	6.868	EPSD	ICGC;COSMIC	6.376	Up-regulation
AGC_PKC_PKCi_PRKCI_ST	Q14247	CTTN	P41743	PRKCI	S282	A283V	283	Missense	proximal	1	no	6.776	6.058	EPSD	ICGC;COSMIC	6.376	Loss
AGC_PKC_PKCi_PRKCI_ST	Q14247	CTTN	P41743	PRKCI	S282	D288H	288	Missense	distal	6	no	6.776	6.925	EPSD	ICGC;COSMIC	6.376	Up-regulation
AGC_PKC_PKCi_PRKCI_ST	Q14247	CTTN	P41743	PRKCI	S282	V275F	275	Missense	distal	-7	no	6.776	6.520	EPSD	ICGC;COSMIC	6.376	Down-regulation
AGC_PKC_PKCi_PRKCI_ST	Q14247	CTTN	P41743	PRKCI	S282	S282F	282	Missense	central	0	yes	6.776	0.000	EPSD	ICGC	6.376	Loss
AGC_PKC_PKCi_PRKCI_ST	Q14247	CTTN	P41743	PRKCI	S282	E278D	278	Missense	distal	-4	no	6.776	6.649	EPSD	ICGC	6.376	Down-regulation
AGC_PKC_PKCi_PRKCI_ST	Q14247	CTTN	P41743	PRKCI	S298	G305V	305	Missense	distal	7	no	10.740	10.672	EPSD	ICGC	6.376	Down-regulation
AGC_PKC_PKCi_PRKCI_ST	P49757	NUMB	P41743	PRKCI	S7	K3N	3	Missense	distal	-4	no	11.823	12.074	EPSD;PhosphoSitePlus	ICGC;COSMIC	6.376	Up-regulation
AGC_PKC_PKCi_PRKCI_ST	P49757	NUMB	P41743	PRKCI	S194	T199P	199	Missense	distal	5	no	7.063	6.929	EPSD	ICGC;COSMIC	6.376	Down-regulation
AGC_PKC_PKCi_PRKCI_ST	P49757	NUMB	P41743	PRKCI	S194	F195L	195	Missense	proximal	1	no	7.063	4.968	EPSD	ICGC;COSMIC	6.376	Loss
AGC_PKC_PKCi_PRKCI_ST	P49757	NUMB	P41743	PRKCI	S276	L283I	283	Missense	distal	7	no	8.385	8.371	EPSD;PhosphoSitePlus	ICGC;COSMIC	6.376	Down-regulation
AGC_PKC_PKCi_PRKCI_ST	Q9UBS0	RPS6KB2	P41743	PRKCI	S379	G386C	386	Missense	distal	7	no	6.505	6.368	EPSD	ICGC	6.376	Loss
AGC_PKC_PKCi_PRKCI_ST	Q9UBS0	RPS6KB2	P41743	PRKCI	S403	F404L	404	Missense	proximal	1	no	7.823	5.727	EPSD	ICGC	6.376	Loss
AGC_PKC_PKCi_PRKCI_ST	Q9UBS0	RPS6KB2	P41743	PRKCI	S410	F404L	404	Missense	distal	-6	no	6.987	7.249	EPSD	ICGC	6.376	Up-regulation
AGC_PKC_PKCi_PRKCI_ST	Q9UBS0	RPS6KB2	P41743	PRKCI	S417	V422I	422	Missense	distal	5	no	7.655	7.779	EPSD	ICGC;COSMIC;CCLE	6.376	Up-regulation
AGC_PKC_PKCi_PRKCI_ST	Q9UBS0	RPS6KB2	P41743	PRKCI	S417	A420V	420	Missense	distal	3	no	7.655	7.912	EPSD	ICGC;COSMIC	6.376	Up-regulation
AGC_PKC_PKCi_PRKCI_ST	P27448	MARK3	P41743	PRKCI	S45	C46F	46	Missense	proximal	1	no	5.175	9.752	EPSD	ICGC	6.376	Gain
AGC_PKC_PKCi_PRKCI_ST	P27448	MARK3	P41743	PRKCI	T491	P493T	493	Missense	proximal	2	no	5.410	6.446	EPSD	ICGC;COSMIC	6.376	Gain
AGC_PKC_PKCi_PRKCI_ST	P27448	MARK3	P41743	PRKCI	T564	S561I	561	Missense	distal	-3	no	9.207	6.752	PhosphoSitePlus	ICGC	6.376	Down-regulation
AGC_PKC_PKCi_PRKCI_ST	P27448	MARK3	P41743	PRKCI	T564	R562H	562	Missense	proximal	-2	no	9.207	8.822	PhosphoSitePlus	ICGC;COSMIC	6.376	Down-regulation
AGC_PKC_PKCi_PRKCI_ST	P27448	MARK3	P41743	PRKCI	T576	R573Q	573	Missense	distal	-3	no	7.161	5.484	EPSD	ICGC;COSMIC	6.376	Loss
AGC_PKC_PKCi_PRKCI_ST	P27448	MARK3	P41743	PRKCI	T576	R573L	573	Missense	distal	-3	no	7.161	4.269	EPSD	ICGC;COSMIC	6.376	Loss
AGC_PKC_PKCi_PRKCI_ST	P27448	MARK3	P41743	PRKCI	S618	R615M	615	Missense	distal	-3	no	12.221	10.150	EPSD	ICGC;COSMIC	6.376	Down-regulation
AGC_PKC_PKCi_PRKCI_ST	Q969H0	FBXW7	P41743	PRKCI	S10	R12I	12	Missense	proximal	2	no	9.953	7.346	PhosphoSitePlus;EPSD	ICGC;COSMIC	6.376	Down-regulation
AGC_PKC_PKCi_PRKCI_ST	Q969H0	FBXW7	P41743	PRKCI	S18	R20I	20	Missense	proximal	2	no	9.121	6.514	EPSD;PhosphoSitePlus	ICGC;COSMIC	6.376	Down-regulation
AGC_PKC_PKCi_PRKCI_ST	Q969H0	FBXW7	P41743	PRKCI	S18	R12I	12	Missense	distal	-6	no	9.121	10.162	EPSD;PhosphoSitePlus	ICGC;COSMIC	6.376	Up-regulation
AGC_PKC_PKCi_PRKCI_ST	Q969H0	FBXW7	P41743	PRKCI	S18	P23S	23	Missense	distal	5	no	9.121	9.101	EPSD;PhosphoSitePlus	ICGC;COSMIC	6.376	Down-regulation
AGC_PKC_PKCi_PRKCI_ST	Q969H0	FBXW7	P41743	PRKCI	S25	R20I	20	Missense	distal	-5	no	8.027	3.678	EPSD	ICGC;COSMIC	6.376	Loss
AGC_PKC_PKCi_PRKCI_ST	Q969H0	FBXW7	P41743	PRKCI	S25	P23S	23	Missense	proximal	-2	no	8.027	8.257	EPSD	ICGC;COSMIC	6.376	Up-regulation
AGC_PKC_PKCi_PRKCI_ST	Q969H0	FBXW7	P41743	PRKCI	S372	G368R	368	Missense	distal	-4	no	8.204	8.368	EPSD	ICGC;COSMIC	6.376	Up-regulation
AGC_PKC_PKCi_PRKCI_ST	Q969H0	FBXW7	P41743	PRKCI	S372	V375L	375	Missense	distal	3	no	8.204	8.258	EPSD	ICGC;COSMIC	6.376	Up-regulation
AGC_PKC_PKCi_PRKCI_ST	Q969H0	FBXW7	P41743	PRKCI	T680	G687E	687	Missense	distal	7	no	7.320	7.363	EPSD	ICGC;COSMIC	6.376	Up-regulation
AGC_PKC_PKCi_PRKCI_ST	Q8TEW0	PARD3	P41743	PRKCI	S25	H20R	20	Missense	distal	-5	no	4.576	6.505	EPSD	ICGC;COSMIC	6.376	Gain
AGC_PKC_PKCi_PRKCI_ST	Q8TEW0	PARD3	P41743	PRKCI	S187	G186W	186	Missense	proximal	-1	no	9.421	9.330	EPSD	ICGC;COSMIC	6.376	Down-regulation
AGC_PKC_PKCi_PRKCI_ST	Q8TEW0	PARD3	P41743	PRKCI	T298	G296S	296	Missense	proximal	-2	no	8.325	8.476	EPSD	ICGC;COSMIC	6.376	Up-regulation
AGC_PKC_PKCi_PRKCI_ST	Q8TEW0	PARD3	P41743	PRKCI	T298	L299M	299	Missense	proximal	1	no	8.325	8.604	EPSD	ICGC;COSMIC	6.376	Up-regulation
AGC_PKC_PKCi_PRKCI_ST	Q8TEW0	PARD3	P41743	PRKCI	T453	T446N	446	Missense	distal	-7	no	9.219	9.149	EPSD	ICGC	6.376	Down-regulation
AGC_PKC_PKCi_PRKCI_ST	Q8TEW0	PARD3	P41743	PRKCI	T453	T453N	453	Missense	central	0	yes	9.219	0.000	EPSD	ICGC;COSMIC	6.376	Loss
AGC_PKC_PKCi_PRKCI_ST	Q8TEW0	PARD3	P41743	PRKCI	T468	K465E	465	Missense	distal	-3	no	7.257	7.129	EPSD	ICGC;COSMIC	6.376	Down-regulation
AGC_PKC_PKCi_PRKCI_ST	Q8TEW0	PARD3	P41743	PRKCI	T468	N461K	461	Missense	distal	-7	no	7.257	7.452	EPSD	ICGC;COSMIC	6.376	Up-regulation
AGC_PKC_PKCi_PRKCI_ST	Q8TEW0	PARD3	P41743	PRKCI	T468	L464H	464	Missense	distal	-4	no	7.257	7.421	EPSD	ICGC;COSMIC	6.376	Up-regulation
AGC_PKC_PKCi_PRKCI_ST	Q8TEW0	PARD3	P41743	PRKCI	T468	E469K	469	Missense	proximal	1	no	7.257	10.920	EPSD	ICGC	6.376	Up-regulation
AGC_PKC_PKCi_PRKCI_ST	Q8TEW0	PARD3	P41743	PRKCI	S523	K522R	522	Missense	proximal	-1	no	7.727	7.920	EPSD	ICGC	6.376	Up-regulation
AGC_PKC_PKCi_PRKCI_ST	Q8TEW0	PARD3	P41743	PRKCI	S523	G521C	521	Missense	proximal	-2	no	7.727	7.216	EPSD	ICGC;COSMIC	6.376	Down-regulation
AGC_PKC_PKCi_PRKCI_ST	Q8TEW0	PARD3	P41743	PRKCI	S529	K522R	522	Missense	distal	-7	no	7.752	7.091	EPSD	ICGC	6.376	Down-regulation
AGC_PKC_PKCi_PRKCI_ST	Q8TEW0	PARD3	P41743	PRKCI	T668	T661S	661	Missense	distal	-7	no	8.256	8.089	EPSD	ICGC;COSMIC	6.376	Down-regulation
AGC_PKC_PKCi_PRKCI_ST	Q8TEW0	PARD3	P41743	PRKCI	S852	K846T	846	Missense	distal	-6	no	8.007	8.048	EPSD	ICGC;COSMIC	6.376	Up-regulation
AGC_PKC_PKCi_PRKCI_ST	Q8TEW0	PARD3	P41743	PRKCI	S955	E950Q	950	Missense	distal	-5	no	5.964	6.429	EPSD	ICGC;COSMIC	6.376	Gain
AGC_PKC_PKCi_PRKCI_ST	Q8TEW0	PARD3	P41743	PRKCI	S1116	P1114L	1114	Missense	proximal	-2	no	8.175	7.980	EPSD	ICGC;COSMIC	6.376	Down-regulation
AGC_PKC_PKCi_PRKCI_ST	Q8TEW0	PARD3	P41743	PRKCI	S1261	G1268V	1268	Missense	distal	7	no	8.207	8.139	EPSD	ICGC;COSMIC	6.376	Down-regulation
AGC_PKC_PKCi_PRKCI_ST	P78545	ELF3	P41743	PRKCI	S254	C260F	260	Missense	distal	6	no	8.404	8.583	EPSD	ICGC	6.376	Up-regulation
AGC_PKC_PKCi_PRKCI_ST	P78545	ELF3	P41743	PRKCI	T325	K320N	320	Missense	distal	-5	no	6.495	5.011	EPSD	ICGC;COSMIC	6.376	Loss
AGC_PKC_PKCi_PRKCI_ST	P78545	ELF3	P41743	PRKCI	T325	R331L	331	Missense	distal	6	no	6.495	6.203	EPSD	ICGC;COSMIC	6.376	Loss
AGC_PKC_PKCi_PRKCI_ST	P78545	ELF3	P41743	PRKCI	T325	Y326C	326	Missense	proximal	1	no	6.495	5.085	EPSD	ICGC;COSMIC	6.376	Loss
AGC_PKC_PKCi_PRKCI_ST	P78545	ELF3	P41743	PRKCI	T325	E327K	327	Missense	proximal	2	no	6.495	6.371	EPSD	ICGC	6.376	Loss
AGC_PKC_PKCi_PRKCI_ST	Q16236	NFE2L2	P41743	PRKCI	S215	M212I	212	Missense	distal	-3	no	6.785	5.344	EPSD	ICGC;COSMIC	6.376	Loss
AGC_PKC_PKCi_PRKCI_ST	Q16236	NFE2L2	P41743	PRKCI	S549	D547N	547	Missense	proximal	-2	no	6.498	6.464	EPSD	ICGC;COSMIC	6.376	Down-regulation
AGC_PKC_PKCi_PRKCI_ST	Q9NPB6	PARD6A	P41743	PRKCI	S11	R10C	10	Missense	proximal	-1	no	7.305	6.646	EPSD	ICGC;COSMIC	6.376	Down-regulation
AGC_PKC_PKCi_PRKCI_ST	Q9NPB6	PARD6A	P41743	PRKCI	S11	S11I	11	Missense	central	0	yes	7.305	0.000	EPSD	ICGC	6.376	Loss
AGC_PKC_PKCi_PRKCI_ST	Q9NPB6	PARD6A	P41743	PRKCI	S11	R10L	10	Missense	proximal	-1	no	7.305	6.921	EPSD	ICGC	6.376	Down-regulation
TK_Syk_ZAP70_Y	Q9UQC2	GAB2	P43403	ZAP70	Y324	P320S	320	Missense	distal	-4	no	6.453	6.518	EPSD	ICGC;COSMIC	5.220	Up-regulation
TK_Syk_ZAP70_Y	P43403	ZAP70	P43403	ZAP70	Y126	R124C	124	Missense	proximal	-2	no	8.864	8.827	EPSD;PhosphoSitePlus	ICGC;COSMIC	5.220	Down-regulation
TK_Syk_ZAP70_Y	P43403	ZAP70	P43403	ZAP70	Y315	P318L	318	Missense	distal	3	no	9.219	7.973	PhosphoSitePlus;EPSD	ICGC;COSMIC	5.220	Down-regulation
TK_Syk_ZAP70_Y	P43403	ZAP70	P43403	ZAP70	Y319	K326N	326	Missense	distal	7	no	11.898	11.851	EPSD;PhosphoSitePlus	ICGC	5.220	Down-regulation
TK_Syk_ZAP70_Y	P43403	ZAP70	P43403	ZAP70	Y319	P318L	318	Missense	proximal	-1	no	11.898	11.538	EPSD;PhosphoSitePlus	ICGC;COSMIC	5.220	Down-regulation
TK_Syk_ZAP70_Y	P43403	ZAP70	P43403	ZAP70	Y569	A570T	570	Missense	proximal	1	no	6.328	7.522	EPSD	ICGC;COSMIC;GDSC;CCLE	5.220	Up-regulation
TK_Syk_ZAP70_Y	Q13094	LCP2	P43403	ZAP70	Y113	P116H	116	Missense	distal	3	no	13.540	11.087	EPSD;PhosphoSitePlus	ICGC	5.220	Down-regulation
TK_Syk_ZAP70_Y	Q13094	LCP2	P43403	ZAP70	Y128	S130F	130	Missense	proximal	2	no	12.246	11.761	EPSD;PhosphoSitePlus	ICGC	5.220	Down-regulation
TK_Syk_ZAP70_Y	Q13094	LCP2	P43403	ZAP70	Y128	G122W	122	Missense	distal	-6	no	12.246	12.352	EPSD;PhosphoSitePlus	ICGC;COSMIC	5.220	Up-regulation
TK_Syk_ZAP70_Y	Q13094	LCP2	P43403	ZAP70	Y145	P147L	147	Missense	proximal	2	no	13.583	12.568	PhosphoSitePlus;EPSD	ICGC;COSMIC	5.220	Down-regulation
TK_Syk_ZAP70_Y	Q13094	LCP2	P43403	ZAP70	Y423	R429L	429	Missense	distal	6	no	5.129	5.274	EPSD	ICGC;COSMIC	5.220	Gain
TK_Syk_ZAP70_Y	Q13094	LCP2	P43403	ZAP70	Y426	V424I	424	Missense	proximal	-2	no	5.194	5.390	EPSD	ICGC	5.220	Gain
TK_Syk_ZAP70_Y	Q9UJU6	DBNL	P43403	ZAP70	Y162	T165A	165	Missense	distal	3	no	7.278	8.354	EPSD	ICGC;COSMIC	5.220	Up-regulation
TK_Syk_ZAP70_Y	Q9UJU6	DBNL	P43403	ZAP70	Y334	E330K	330	Missense	distal	-4	no	13.193	12.922	PhosphoSitePlus;EPSD	ICGC;COSMIC	5.220	Down-regulation
TK_Syk_ZAP70_Y	Q9UJU6	DBNL	P43403	ZAP70	Y334	P338L	338	Missense	distal	4	no	13.193	12.890	PhosphoSitePlus;EPSD	ICGC	5.220	Down-regulation
TK_Syk_ZAP70_Y	Q9UJU6	DBNL	P43403	ZAP70	Y344	P338L	338	Missense	distal	-6	no	10.218	9.604	EPSD;PhosphoSitePlus	ICGC	5.220	Down-regulation
TK_Syk_ZAP70_Y	Q8N1K5	THEMIS	P43403	ZAP70	Y174	G171E	171	Missense	distal	-3	no	3.677	6.362	EPSD	ICGC	5.220	Gain
TK_Syk_ZAP70_Y	Q8N1K5	THEMIS	P43403	ZAP70	Y540	R544L	544	Missense	distal	4	no	11.017	10.839	EPSD;PhosphoSitePlus	ICGC;COSMIC	5.220	Down-regulation
TK_Syk_ZAP70_Y	Q8N1K5	THEMIS	P43403	ZAP70	Y540	R544Q	544	Missense	distal	4	no	11.017	10.938	EPSD;PhosphoSitePlus	ICGC;COSMIC;GDSC;CCLE	5.220	Down-regulation
TK_Syk_ZAP70_Y	Q8N1K5	THEMIS	P43403	ZAP70	Y540	Y546C	546	Missense	distal	6	no	11.017	11.092	EPSD;PhosphoSitePlus	ICGC;COSMIC	5.220	Up-regulation
TK_Syk_ZAP70_Y	Q8N1K5	THEMIS	P43403	ZAP70	Y541	R544L	544	Missense	distal	3	no	10.532	10.100	PhosphoSitePlus;EPSD	ICGC;COSMIC	5.220	Down-regulation
TK_Syk_ZAP70_Y	Q8N1K5	THEMIS	P43403	ZAP70	Y541	S548T	548	Missense	distal	7	no	10.532	10.561	PhosphoSitePlus;EPSD	ICGC;COSMIC	5.220	Up-regulation
TK_Syk_ZAP70_Y	Q8N1K5	THEMIS	P43403	ZAP70	Y541	R544Q	544	Missense	distal	3	no	10.532	9.634	PhosphoSitePlus;EPSD	ICGC;COSMIC;GDSC;CCLE	5.220	Down-regulation
TK_Syk_ZAP70_Y	Q8N1K5	THEMIS	P43403	ZAP70	Y541	Y546C	546	Missense	distal	5	no	10.532	10.919	PhosphoSitePlus;EPSD	ICGC;COSMIC	5.220	Up-regulation
TK_Syk_ZAP70_Y	Q16539	MAPK14	P43403	ZAP70	Y35	V38L	38	Missense	distal	3	no	5.875	5.623	EPSD	ICGC;COSMIC	5.220	Down-regulation
TK_Syk_ZAP70_Y	Q16539	MAPK14	P43403	ZAP70	Y323	D321N	321	Missense	proximal	-2	no	11.786	11.840	PhosphoSitePlus	ICGC	5.220	Up-regulation
TK_Syk_ZAP70_Y	P51452	DUSP3	P43403	ZAP70	Y23	S20R	20	Missense	distal	-3	no	6.312	4.693	EPSD	ICGC;COSMIC	5.220	Loss
TK_Syk_ZAP70_Y	P51452	DUSP3	P43403	ZAP70	Y23	C30R	30	Missense	distal	7	no	6.312	6.305	EPSD	ICGC;COSMIC	5.220	Down-regulation
TK_Syk_ZAP70_Y	P51452	DUSP3	P43403	ZAP70	Y38	G40V	40	Missense	proximal	2	no	11.680	12.034	EPSD;PhosphoSitePlus	ICGC;COSMIC	5.220	Up-regulation
TK_Syk_ZAP70_Y	P51452	DUSP3	P43403	ZAP70	Y38	E32K	32	Missense	distal	-6	no	11.680	10.446	EPSD;PhosphoSitePlus	ICGC	5.220	Down-regulation
TK_Syk_ZAP70_Y	P51452	DUSP3	P43403	ZAP70	Y38	R36Q	36	Missense	proximal	-2	no	11.680	11.809	EPSD;PhosphoSitePlus	ICGC;COSMIC	5.220	Up-regulation
TK_Syk_ZAP70_Y	P51452	DUSP3	P43403	ZAP70	Y138	P132Q	132	Missense	distal	-6	no	11.685	10.759	PhosphoSitePlus;EPSD	ICGC;COSMIC	5.220	Down-regulation
Atypical_BCR_BCR_ST	P27348	YWHAQ	P11274	BCR	T205	N207S	207	Missense	proximal	2	no	2.159	2.137	EPSD	ICGC;COSMIC	1.927	Down-regulation
Atypical_BCR_BCR_ST	P27348	YWHAQ	P11274	BCR	S232	D238V	238	Missense	distal	6	no	17.130	16.989	PhosphoSitePlus	ICGC;COSMIC	1.927	Down-regulation
Atypical_BCR_BCR_ST	P27348	YWHAQ	P11274	BCR	S232	A239E	239	Missense	distal	7	no	17.130	16.863	PhosphoSitePlus	ICGC	1.927	Down-regulation
Atypical_BCR_BCR_ST	P63104	YWHAZ	P11274	BCR	S58	A54P	54	Missense	distal	-4	no	3.211	3.222	EPSD	ICGC;COSMIC	1.927	Up-regulation
Atypical_BCR_BCR_ST	P63104	YWHAZ	P11274	BCR	T205	A201S	201	Missense	distal	-4	no	2.352	2.354	EPSD	ICGC;COSMIC	1.927	Up-regulation
Atypical_BCR_BCR_ST	P63104	YWHAZ	P11274	BCR	T232	Q233K	233	Missense	proximal	1	no	16.666	16.557	PhosphoSitePlus	ICGC	1.927	Down-regulation
Other_WEE_Myt1_PKMYT1_ST	P06493	CDK1	Q99640	PKMYT1	T14	T14A	14	Missense	central	0	yes	4.767	0.000	PhosphoSitePlus;EPSD	ICGC;COSMIC	1.669	Loss
Other_WEE_Myt1_PKMYT1_ST	P06493	CDK1	Q99640	PKMYT1	S53	R59H	59	Missense	distal	6	no	1.729	1.725	EPSD	ICGC;COSMIC	1.669	Down-regulation
Other_WEE_Myt1_PKMYT1_ST	P06493	CDK1	Q99640	PKMYT1	S53	R50L	50	Missense	distal	-3	no	1.729	1.763	EPSD	ICGC;COSMIC	1.669	Up-regulation
Other_WEE_Myt1_PKMYT1_ST	P06493	CDK1	Q99640	PKMYT1	S171	P172Q	172	Missense	proximal	1	no	1.486	1.686	EPSD	ICGC;COSMIC	1.669	Gain
Other_NEK_NEK6_NEK7_ST	Q15058	KIF14	Q8TDX7	NEK7	S12	S5N	5	Missense	distal	-7	no	2.518	4.340	EPSD	ICGC;COSMIC;GDSC;CCLE	3.120	Gain
Other_NEK_NEK6_NEK7_ST	Q15058	KIF14	Q8TDX7	NEK7	S56	P52S	52	Missense	distal	-4	no	8.347	8.297	PhosphoSitePlus;EPSD	ICGC	3.120	Down-regulation
Other_NEK_NEK6_NEK7_ST	Q15058	KIF14	Q8TDX7	NEK7	T144	M143I	143	Missense	proximal	-1	no	3.211	3.206	EPSD	ICGC	3.120	Down-regulation
Other_NEK_NEK6_NEK7_ST	Q15058	KIF14	Q8TDX7	NEK7	T360	V365I	365	Missense	distal	5	no	3.578	3.641	EPSD	ICGC;COSMIC	3.120	Up-regulation
Other_NEK_NEK6_NEK7_ST	Q15058	KIF14	Q8TDX7	NEK7	T360	Q358H	358	Missense	proximal	-2	no	3.578	3.484	EPSD	ICGC;COSMIC	3.120	Down-regulation
Other_NEK_NEK6_NEK7_ST	Q15058	KIF14	Q8TDX7	NEK7	T360	P367H	367	Missense	distal	7	no	3.578	3.658	EPSD	ICGC	3.120	Up-regulation
Other_NEK_NEK6_NEK7_ST	Q15058	KIF14	Q8TDX7	NEK7	T360	P367T	367	Missense	distal	7	no	3.578	3.351	EPSD	ICGC	3.120	Down-regulation
Other_NEK_NEK6_NEK7_ST	Q15058	KIF14	Q8TDX7	NEK7	T360	A362E	362	Missense	proximal	2	no	3.578	3.641	EPSD	ICGC	3.120	Up-regulation
Other_NEK_NEK6_NEK7_ST	Q15058	KIF14	Q8TDX7	NEK7	S607	H614D	614	Missense	distal	7	no	7.160	7.133	EPSD;PhosphoSitePlus	ICGC;COSMIC	3.120	Down-regulation
Other_NEK_NEK6_NEK7_ST	Q15058	KIF14	Q8TDX7	NEK7	S607	T612M	612	Missense	distal	5	no	7.160	7.250	EPSD;PhosphoSitePlus	ICGC;COSMIC	3.120	Up-regulation
Other_NEK_NEK6_NEK7_ST	Q15058	KIF14	Q8TDX7	NEK7	S607	H614Q	614	Missense	distal	7	no	7.160	6.935	EPSD;PhosphoSitePlus	ICGC	3.120	Down-regulation
Other_NEK_NEK6_NEK7_ST	Q15058	KIF14	Q8TDX7	NEK7	S607	G606D	606	Missense	proximal	-1	no	7.160	7.148	EPSD;PhosphoSitePlus	ICGC;COSMIC	3.120	Down-regulation
Other_NEK_NEK6_NEK7_ST	Q15058	KIF14	Q8TDX7	NEK7	T632	T632N	632	Missense	central	0	yes	3.875	0.000	EPSD	ICGC	3.120	Loss
Other_NEK_NEK6_NEK7_ST	Q15058	KIF14	Q8TDX7	NEK7	S1186	S1192G	1192	Missense	distal	6	no	3.032	3.273	EPSD	ICGC	3.120	Gain
Other_NEK_NEK6_NEK7_ST	Q15058	KIF14	Q8TDX7	NEK7	S1217	S1219L	1219	Missense	proximal	2	no	7.414	7.609	EPSD;PhosphoSitePlus	ICGC	3.120	Up-regulation
Other_NEK_NEK6_NEK7_ST	Q15058	KIF14	Q8TDX7	NEK7	S1219	S1219L	1219	Missense	central	0	yes	7.531	0.000	EPSD;PhosphoSitePlus	ICGC	3.120	Loss
Other_NEK_NEK6_NEK7_ST	Q15058	KIF14	Q8TDX7	NEK7	S1220	S1219L	1219	Missense	proximal	-1	no	7.362	7.339	EPSD;PhosphoSitePlus	ICGC	3.120	Down-regulation
Other_NEK_NEK6_NEK7_ST	Q15058	KIF14	Q8TDX7	NEK7	S1466	L1463F	1463	Missense	distal	-3	no	3.633	2.655	EPSD	ICGC;COSMIC	3.120	Loss
Other_NEK_NEK6_NEK7_ST	Q15058	KIF14	Q8TDX7	NEK7	S1547	P1552S	1552	Missense	distal	5	no	4.014	3.778	EPSD	ICGC;COSMIC	3.120	Down-regulation
Other_NEK_NEK6_NEK7_ST	P54274	TERF1	Q8TDX7	NEK7	T24	D17N	17	Missense	distal	-7	no	1.409	3.272	EPSD	ICGC;GDSC;CCLE	3.120	Gain
Other_NEK_NEK6_NEK7_ST	P52732	KIF11	Q8TDX7	NEK7	S7	S3L	3	Missense	distal	-4	no	3.028	3.161	EPSD	ICGC;COSMIC;GDSC;CCLE	3.120	Gain
Other_NEK_NEK6_NEK7_ST	P52732	KIF11	Q8TDX7	NEK7	S36	H38L	38	Missense	proximal	2	no	4.510	4.394	EPSD	ICGC;COSMIC	3.120	Down-regulation
Other_NEK_NEK6_NEK7_ST	P52732	KIF11	Q8TDX7	NEK7	S36	V41L	41	Missense	distal	5	no	4.510	4.456	EPSD	ICGC	3.120	Down-regulation
Other_NEK_NEK6_NEK7_ST	P52732	KIF11	Q8TDX7	NEK7	S240	V238F	238	Missense	proximal	-2	no	4.407	4.415	EPSD	ICGC	3.120	Up-regulation
Other_NEK_NEK6_NEK7_ST	P52732	KIF11	Q8TDX7	NEK7	S240	R234L	234	Missense	distal	-6	no	4.407	4.161	EPSD	ICGC	3.120	Down-regulation
Other_NEK_NEK6_NEK7_ST	P52732	KIF11	Q8TDX7	NEK7	T294	V298I	298	Missense	distal	4	no	5.252	5.415	EPSD	ICGC;COSMIC	3.120	Up-regulation
Other_NEK_NEK6_NEK7_ST	P52732	KIF11	Q8TDX7	NEK7	T463	E470K	470	Missense	distal	7	no	3.451	3.397	EPSD	ICGC;COSMIC	3.120	Down-regulation
CMGC_DYRK_DYRK2_DYRK3_ST	Q96B36	AKT1S1	O43781	DYRK3	T73	A75T	75	Missense	proximal	2	no	2.208	2.175	EPSD	ICGC;COSMIC	1.682	Down-regulation
CMGC_DYRK_DYRK2_DYRK3_ST	Q96B36	AKT1S1	O43781	DYRK3	T97	A99V	99	Missense	proximal	2	no	2.413	2.323	EPSD	ICGC;COSMIC	1.682	Down-regulation
CMGC_DYRK_DYRK2_DYRK3_ST	Q96B36	AKT1S1	O43781	DYRK3	T97	A99S	99	Missense	proximal	2	no	2.413	2.363	EPSD	ICGC;COSMIC	1.682	Down-regulation
CMGC_DYRK_DYRK2_DYRK3_ST	Q96B36	AKT1S1	O43781	DYRK3	T246	R243P	243	Missense	distal	-3	no	3.859	2.112	PhosphoSitePlus	ICGC;COSMIC	1.682	Down-regulation
TK_Tec_TXK_Y	P42681	TXK	P42681	TXK	Y91	A89E	89	Missense	proximal	-2	no	5.928	5.288	EPSD;PhosphoSitePlus	ICGC	1.475	Down-regulation
TK_Tec_TXK_Y	P42681	TXK	P42681	TXK	Y91	E97K	97	Missense	distal	6	no	5.928	5.930	EPSD;PhosphoSitePlus	ICGC;COSMIC	1.475	Up-regulation
TK_Tec_TXK_Y	P42681	TXK	P42681	TXK	Y420	A426T	426	Missense	distal	6	no	5.628	5.626	PhosphoSitePlus;EPSD	ICGC;COSMIC	1.475	Down-regulation
TK_Tec_TXK_Y	P42681	TXK	P42681	TXK	Y420	V415F	415	Missense	distal	-5	no	5.628	5.676	PhosphoSitePlus;EPSD	ICGC;COSMIC	1.475	Up-regulation
TKL_STKR_STKR1_BMPR1B_ST	Q15796	SMAD2	O00238	BMPR1B	S47	K53N	53	Missense	distal	6	no	-0.987	-1.056	EPSD	ICGC;COSMIC	-1.120	Down-regulation
TKL_STKR_STKR1_BMPR1B_ST	Q15796	SMAD2	O00238	BMPR1B	S317	R310M	310	Missense	distal	-7	no	-1.119	-1.109	EPSD	ICGC;COSMIC	-1.120	Up-regulation
TKL_STKR_STKR1_BMPR1B_ST	Q15796	SMAD2	O00238	BMPR1B	S317	T324K	324	Missense	distal	7	no	-1.119	-1.047	EPSD	ICGC	-1.120	Up-regulation
TKL_STKR_STKR1_BMPR1B_ST	Q15796	SMAD2	O00238	BMPR1B	S317	G314V	314	Missense	distal	-3	no	-1.119	-1.118	EPSD	ICGC;COSMIC	-1.120	Up-regulation
TKL_STKR_STKR1_BMPR1B_ST	Q15796	SMAD2	O00238	BMPR1B	S317	L316F	316	Missense	proximal	-1	no	-1.119	-1.116	EPSD	ICGC	-1.120	Up-regulation
TKL_STKR_STKR1_BMPR1B_ST	Q15796	SMAD2	O00238	BMPR1B	S417	R415I	415	Missense	proximal	-2	no	-1.094	-1.093	EPSD	ICGC;COSMIC	-1.120	Up-regulation
TKL_STKR_STKR1_BMPR1B_ST	Q15797	SMAD1	O00238	BMPR1B	T10	S8F	8	Missense	proximal	-2	no	-1.075	-1.071	EPSD	ICGC	-1.120	Up-regulation
TKL_STKR_STKR1_BMPR1B_ST	Q15797	SMAD1	O00238	BMPR1B	T10	S5R	5	Missense	distal	-5	no	-1.075	-1.076	EPSD	ICGC	-1.120	Down-regulation
TKL_STKR_STKR1_BMPR1B_ST	Q15797	SMAD1	O00238	BMPR1B	S11	S8F	8	Missense	distal	-3	no	-1.096	-1.095	EPSD	ICGC	-1.120	Up-regulation
TKL_STKR_STKR1_BMPR1B_ST	Q15797	SMAD1	O00238	BMPR1B	S11	S5R	5	Missense	distal	-6	no	-1.096	-1.097	EPSD	ICGC	-1.120	Down-regulation
TKL_STKR_STKR1_BMPR1B_ST	Q15797	SMAD1	O00238	BMPR1B	S11	L18I	18	Missense	distal	7	no	-1.096	-1.052	EPSD	ICGC;COSMIC	-1.120	Up-regulation
TKL_STKR_STKR1_BMPR1B_ST	Q15797	SMAD1	O00238	BMPR1B	S462	P457L	457	Missense	distal	-5	no	-0.890	-0.910	EPSD;PhosphoSitePlus	ICGC;COSMIC	-1.120	Down-regulation
TKL_STKR_STKR1_BMPR1B_ST	Q15797	SMAD1	O00238	BMPR1B	S463	P457L	457	Missense	distal	-6	no	-0.813	-0.816	EPSD;PhosphoSitePlus	ICGC;COSMIC	-1.120	Down-regulation
TK_Jak_TYK2_Y	O15304	SIVA1	P29597	TYK2	Y53	V57M	57	Missense	distal	4	no	41.028	42.008	EPSD;PhosphoSitePlus	ICGC;COSMIC	21.015	Up-regulation
TK_Jak_TYK2_Y	P40763	STAT3	P29597	TYK2	Y640	P639Q	639	Missense	proximal	-1	no	44.286	46.958	PhosphoSitePlus	ICGC	21.015	Up-regulation
TK_Jak_TYK2_Y	P40763	STAT3	P29597	TYK2	Y640	T641R	641	Missense	proximal	1	no	44.286	44.250	PhosphoSitePlus	ICGC;COSMIC	21.015	Down-regulation
TK_Jak_TYK2_Y	P40763	STAT3	P29597	TYK2	Y640	N647Y	647	Missense	distal	7	no	44.286	42.345	PhosphoSitePlus	ICGC;COSMIC	21.015	Down-regulation
TK_Jak_TYK2_Y	P40763	STAT3	P29597	TYK2	Y686	S691C	691	Missense	distal	5	no	19.272	23.889	EPSD	ICGC;COSMIC	21.015	Gain
TK_Fak_PTK2B_Y	O15259	NPHP1	Q14289	PTK2B	Y46	Q47K	47	Missense	proximal	1	no	510.001	504.557	EPSD;PhosphoSitePlus	ICGC	366.093	Down-regulation
TK_Fak_PTK2B_Y	O15259	NPHP1	Q14289	PTK2B	Y46	Q43K	43	Missense	distal	-3	no	510.001	497.885	EPSD;PhosphoSitePlus	ICGC	366.093	Down-regulation
TK_Fak_PTK2B_Y	Q14247	CTTN	Q14289	PTK2B	Y162	G160S	160	Missense	proximal	-2	no	347.542	395.462	EPSD	ICGC;COSMIC	366.093	Gain
TK_Fak_PTK2B_Y	Q14247	CTTN	Q14289	PTK2B	Y199	G196D	196	Missense	distal	-3	no	357.445	451.152	EPSD	ICGC;COSMIC	366.093	Gain
TK_Fak_PTK2B_Y	Q14247	CTTN	Q14289	PTK2B	Y199	G197D	197	Missense	proximal	-2	no	357.445	413.574	EPSD	ICGC;COSMIC	366.093	Gain
TK_Fak_PTK2B_Y	Q14247	CTTN	Q14289	PTK2B	Y310	G307S	307	Missense	distal	-3	no	328.687	425.807	EPSD	ICGC;COSMIC	366.093	Gain
TK_Fak_PTK2B_Y	Q14247	CTTN	Q14289	PTK2B	Y421	L415P	415	Missense	distal	-6	no	622.353	622.185	EPSD;PhosphoSitePlus	ICGC	366.093	Down-regulation
TK_Fak_PTK2B_Y	Q14247	CTTN	Q14289	PTK2B	Y421	A424V	424	Missense	distal	3	no	622.353	616.142	EPSD;PhosphoSitePlus	ICGC;COSMIC;GDSC	366.093	Down-regulation
TK_Fak_PTK2B_Y	Q14247	CTTN	Q14289	PTK2B	Y433	T440M	440	Missense	distal	7	no	368.960	365.817	EPSD	ICGC	366.093	Loss
TK_Fak_PTK2B_Y	Q14247	CTTN	Q14289	PTK2B	Y433	S438I	438	Missense	distal	5	no	368.960	295.535	EPSD	ICGC	366.093	Loss
TK_Fak_PTK2B_Y	Q14247	CTTN	Q14289	PTK2B	Y446	A450G	450	Missense	distal	4	no	392.624	370.948	EPSD	ICGC;COSMIC	366.093	Down-regulation
TK_Fak_PTK2B_Y	Q14247	CTTN	Q14289	PTK2B	Y446	T440M	440	Missense	distal	-6	no	392.624	394.190	EPSD	ICGC	366.093	Up-regulation
TK_Fak_PTK2B_Y	Q14247	CTTN	Q14289	PTK2B	Y446	E441D	441	Missense	distal	-5	no	392.624	392.291	EPSD	ICGC	366.093	Down-regulation
TK_Fak_PTK2B_Y	Q14247	CTTN	Q14289	PTK2B	Y446	A450V	450	Missense	distal	4	no	392.624	365.704	EPSD	ICGC;COSMIC	366.093	Loss
TK_Fak_PTK2B_Y	Q14247	CTTN	Q14289	PTK2B	Y453	A450G	450	Missense	distal	-3	no	513.178	517.490	EPSD	ICGC;COSMIC	366.093	Up-regulation
TK_Fak_PTK2B_Y	Q14247	CTTN	Q14289	PTK2B	Y453	R454Q	454	Missense	proximal	1	no	513.178	509.622	EPSD	ICGC	366.093	Down-regulation
TK_Fak_PTK2B_Y	Q14247	CTTN	Q14289	PTK2B	Y453	A450V	450	Missense	distal	-3	no	513.178	433.196	EPSD	ICGC;COSMIC	366.093	Down-regulation
TK_Fak_PTK2B_Y	Q14247	CTTN	Q14289	PTK2B	Y470	A463P	463	Missense	distal	-7	no	658.507	659.109	EPSD;PhosphoSitePlus	ICGC;COSMIC	366.093	Up-regulation
TK_Fak_PTK2B_Y	Q14247	CTTN	Q14289	PTK2B	Y470	P476S	476	Missense	distal	6	no	658.507	658.886	EPSD;PhosphoSitePlus	ICGC;COSMIC	366.093	Up-regulation
TK_Fak_PTK2B_Y	Q14247	CTTN	Q14289	PTK2B	Y479	P476S	476	Missense	distal	-3	no	333.850	457.678	EPSD	ICGC;COSMIC	366.093	Gain
TK_Fak_PTK2B_Y	Q14247	CTTN	Q14289	PTK2B	Y486	D483N	483	Missense	distal	-3	no	663.322	591.312	PhosphoSitePlus;EPSD	ICGC;COSMIC	366.093	Down-regulation
TK_Fak_PTK2B_Y	Q14247	CTTN	Q14289	PTK2B	Y486	D487N	487	Missense	proximal	1	no	663.322	656.237	PhosphoSitePlus;EPSD	ICGC;COSMIC;GDSC	366.093	Down-regulation
TK_Fak_PTK2B_Y	Q14247	CTTN	Q14289	PTK2B	Y486	P480A	480	Missense	distal	-6	no	663.322	661.384	PhosphoSitePlus;EPSD	ICGC;COSMIC	366.093	Down-regulation
TK_Fak_PTK2B_Y	Q14247	CTTN	Q14289	PTK2B	Y486	D492Y	492	Missense	distal	6	no	663.322	662.935	PhosphoSitePlus;EPSD	ICGC;COSMIC	366.093	Down-regulation
TK_Fak_PTK2B_Y	Q14247	CTTN	Q14289	PTK2B	Y486	D492H	492	Missense	distal	6	no	663.322	663.030	PhosphoSitePlus;EPSD	ICGC;COSMIC	366.093	Down-regulation
TK_Fak_PTK2B_Y	Q14247	CTTN	Q14289	PTK2B	Y486	P480S	480	Missense	distal	-6	no	663.322	660.626	PhosphoSitePlus;EPSD	ICGC;COSMIC	366.093	Down-regulation
TK_Fak_PTK2B_Y	Q14247	CTTN	Q14289	PTK2B	Y486	L493M	493	Missense	distal	7	no	663.322	664.733	PhosphoSitePlus;EPSD	ICGC;COSMIC	366.093	Up-regulation
TK_Fak_PTK2B_Y	P37840	SNCA	Q14289	PTK2B	Y125	P120T	120	Missense	distal	-5	no	505.058	508.680	PhosphoSitePlus	ICGC	366.093	Up-regulation
TK_Fak_PTK2B_Y	P37840	SNCA	Q14289	PTK2B	Y133	Q134K	134	Missense	proximal	1	no	429.398	423.954	EPSD	ICGC;COSMIC	366.093	Down-regulation
TK_Fak_PTK2B_Y	Q14289	PTK2B	Q14289	PTK2B	Y402	D407N	407	Missense	distal	5	no	715.215	685.614	PhosphoSitePlus	ICGC;COSMIC	366.093	Down-regulation
TK_Fak_PTK2B_Y	Q14289	PTK2B	Q14289	PTK2B	Y402	T409A	409	Missense	distal	7	no	715.215	714.660	PhosphoSitePlus	ICGC	366.093	Down-regulation
TK_Fak_PTK2B_Y	Q14289	PTK2B	Q14289	PTK2B	Y402	E404D	404	Missense	proximal	2	no	715.215	715.684	PhosphoSitePlus	ICGC	366.093	Up-regulation
TK_Fak_PTK2B_Y	Q14289	PTK2B	Q14289	PTK2B	Y579	R572L	572	Missense	distal	-7	no	391.776	393.199	EPSD	ICGC	366.093	Up-regulation
TK_Fak_PTK2B_Y	Q14289	PTK2B	Q14289	PTK2B	Y579	R572W	572	Missense	distal	-7	no	391.776	393.110	EPSD	ICGC;GDSC;CCLE	366.093	Up-regulation
TK_Fak_PTK2B_Y	Q14289	PTK2B	Q14289	PTK2B	Y579	I574F	574	Missense	distal	-5	no	391.776	389.143	EPSD	ICGC;COSMIC	366.093	Down-regulation
TK_Fak_PTK2B_Y	Q14289	PTK2B	Q14289	PTK2B	Y580	I574F	574	Missense	distal	-6	no	443.113	444.265	EPSD	ICGC;COSMIC	366.093	Up-regulation
TK_Fak_PTK2B_Y	Q14289	PTK2B	Q14289	PTK2B	Y683	V682I	682	Missense	proximal	-1	no	377.698	389.604	EPSD	ICGC;COSMIC;CCLE	366.093	Up-regulation
TK_Fak_PTK2B_Y	Q14289	PTK2B	Q14289	PTK2B	Y683	Q684R	684	Missense	proximal	1	no	377.698	381.254	EPSD	ICGC;COSMIC	366.093	Up-regulation
TK_Fak_PTK2B_Y	Q05397	PTK2	Q14289	PTK2B	Y194	A187T	187	Missense	distal	-7	no	377.688	376.325	EPSD	ICGC;COSMIC	366.093	Down-regulation
TK_Fak_PTK2B_Y	Q05397	PTK2	Q14289	PTK2B	Y441	D435N	435	Missense	distal	-6	no	421.327	421.848	EPSD	ICGC;COSMIC	366.093	Up-regulation
TK_Fak_PTK2B_Y	Q05397	PTK2	Q14289	PTK2B	Y441	H437N	437	Missense	distal	-4	no	421.327	463.590	EPSD	ICGC	366.093	Up-regulation
TK_Fak_PTK2B_Y	P29474	NOS3	Q14289	PTK2B	Y657	G651V	651	Missense	distal	-6	no	449.011	449.629	PhosphoSitePlus	ICGC	366.093	Up-regulation
TK_Fak_PTK2B_Y	Q13586	STIM1	Q14289	PTK2B	Y130	S126L	126	Missense	distal	-4	no	422.914	279.006	EPSD	ICGC	366.093	Loss
AGC_RSK_RSKp70_RPS6KB2_ST	P49841	GSK3B	Q9UBS0	RPS6KB2	T7	A11S	11	Missense	distal	4	no	4.056	4.311	EPSD	ICGC;COSMIC	4.103	Gain
AGC_RSK_RSKp70_RPS6KB2_ST	P49841	GSK3B	Q9UBS0	RPS6KB2	S9	A11S	11	Missense	proximal	2	no	9.449	9.301	PhosphoSitePlus	ICGC;COSMIC	4.103	Down-regulation
AGC_RSK_RSKp70_RPS6KB2_ST	P49841	GSK3B	Q9UBS0	RPS6KB2	S147	A149D	149	Missense	proximal	2	no	5.899	5.811	EPSD	ICGC	4.103	Down-regulation
AGC_RSK_RSKp70_RPS6KB2_ST	P49841	GSK3B	Q9UBS0	RPS6KB2	S147	T152R	152	Missense	distal	5	no	5.899	5.934	EPSD	ICGC;COSMIC	4.103	Up-regulation
AGC_RSK_RSKp70_RPS6KB2_ST	P49841	GSK3B	Q9UBS0	RPS6KB2	S147	Q151R	151	Missense	distal	4	no	5.899	5.866	EPSD	ICGC;COSMIC	4.103	Down-regulation
AGC_RSK_RSKp70_RPS6KB2_ST	P49841	GSK3B	Q9UBS0	RPS6KB2	T408	G406R	406	Missense	proximal	-2	no	4.930	5.315	EPSD	ICGC;COSMIC	4.103	Up-regulation
AGC_RSK_RSKp70_RPS6KB2_ST	P05783	KRT18	Q9UBS0	RPS6KB2	S30	A32S	32	Missense	proximal	2	no	5.083	4.934	EPSD	ICGC;COSMIC	4.103	Down-regulation
AGC_RSK_RSKp70_RPS6KB2_ST	P05783	KRT18	Q9UBS0	RPS6KB2	S30	A26T	26	Missense	distal	-4	no	5.083	5.276	EPSD	ICGC;COSMIC	4.103	Up-regulation
AGC_RSK_RSKp70_RPS6KB2_ST	P05783	KRT18	Q9UBS0	RPS6KB2	S30	S34R	34	Missense	distal	4	no	5.083	4.796	EPSD	ICGC;COSMIC	4.103	Down-regulation
AGC_RSK_RSKp70_RPS6KB2_ST	P05783	KRT18	Q9UBS0	RPS6KB2	S30	P28Q	28	Missense	proximal	-2	no	5.083	5.210	EPSD	ICGC;COSMIC	4.103	Up-regulation
AGC_RSK_RSKp70_RPS6KB2_ST	P05783	KRT18	Q9UBS0	RPS6KB2	S30	R27W	27	Missense	distal	-3	no	5.083	0.264	EPSD	ICGC;COSMIC	4.103	Loss
AGC_RSK_RSKp70_RPS6KB2_ST	P05783	KRT18	Q9UBS0	RPS6KB2	S30	G25C	25	Missense	distal	-5	no	5.083	5.128	EPSD	ICGC;COSMIC	4.103	Up-regulation
AGC_RSK_RSKp70_RPS6KB2_ST	P05783	KRT18	Q9UBS0	RPS6KB2	S30	A37T	37	Missense	distal	7	no	5.083	5.086	EPSD	ICGC;COSMIC	4.103	Up-regulation
AGC_RSK_RSKp70_RPS6KB2_ST	P05783	KRT18	Q9UBS0	RPS6KB2	S53	V48M	48	Missense	distal	-5	no	9.837	9.867	PhosphoSitePlus	ICGC;COSMIC	4.103	Up-regulation
AGC_RSK_RSKp70_RPS6KB2_ST	P05783	KRT18	Q9UBS0	RPS6KB2	S53	R50C	50	Missense	distal	-3	no	9.837	4.545	PhosphoSitePlus	ICGC;COSMIC	4.103	Down-regulation
AGC_RSK_RSKp70_RPS6KB2_ST	P05783	KRT18	Q9UBS0	RPS6KB2	S53	G56D	56	Missense	distal	3	no	9.837	9.785	PhosphoSitePlus	ICGC;COSMIC	4.103	Down-regulation
AGC_RSK_RSKp70_RPS6KB2_ST	P05783	KRT18	Q9UBS0	RPS6KB2	S53	G59W	59	Missense	distal	6	no	9.837	9.752	PhosphoSitePlus	ICGC;COSMIC	4.103	Down-regulation
AGC_RSK_RSKp70_RPS6KB2_ST	P05783	KRT18	Q9UBS0	RPS6KB2	S53	I46T	46	Missense	distal	-7	no	9.837	9.676	PhosphoSitePlus	ICGC;COSMIC	4.103	Down-regulation
AGC_RSK_RSKp70_RPS6KB2_ST	P05783	KRT18	Q9UBS0	RPS6KB2	S93	D89N	89	Missense	distal	-4	no	7.353	7.176	EPSD	ICGC;COSMIC	4.103	Down-regulation
AGC_RSK_RSKp70_RPS6KB2_ST	P05783	KRT18	Q9UBS0	RPS6KB2	S93	A92P	92	Missense	proximal	-1	no	7.353	7.018	EPSD	ICGC;COSMIC	4.103	Down-regulation
AGC_RSK_RSKp70_RPS6KB2_ST	P05783	KRT18	Q9UBS0	RPS6KB2	S93	S86N	86	Missense	distal	-7	no	7.353	7.555	EPSD	ICGC;COSMIC	4.103	Up-regulation
AGC_RSK_RSKp70_RPS6KB2_ST	P05783	KRT18	Q9UBS0	RPS6KB2	S100	R106L	106	Missense	distal	6	no	6.236	6.182	EPSD	ICGC;COSMIC	4.103	Down-regulation
AGC_RSK_RSKp70_RPS6KB2_ST	P05783	KRT18	Q9UBS0	RPS6KB2	S100	R107K	107	Missense	distal	7	no	6.236	6.235	EPSD	ICGC;COSMIC	4.103	Down-regulation
AGC_RSK_RSKp70_RPS6KB2_ST	P05783	KRT18	Q9UBS0	RPS6KB2	S100	R106W	106	Missense	distal	6	no	6.236	6.278	EPSD	ICGC;COSMIC	4.103	Up-regulation
AGC_RSK_RSKp70_RPS6KB2_ST	P05783	KRT18	Q9UBS0	RPS6KB2	S100	T103N	103	Missense	distal	3	no	6.236	6.314	EPSD	ICGC;COSMIC	4.103	Up-regulation
AGC_RSK_RSKp70_RPS6KB2_ST	P05783	KRT18	Q9UBS0	RPS6KB2	S100	E102D	102	Missense	proximal	2	no	6.236	6.189	EPSD	ICGC;COSMIC	4.103	Down-regulation
AGC_RSK_RSKp70_RPS6KB2_ST	P05783	KRT18	Q9UBS0	RPS6KB2	S110	R106L	106	Missense	distal	-4	no	5.859	5.754	EPSD	ICGC;COSMIC	4.103	Down-regulation
AGC_RSK_RSKp70_RPS6KB2_ST	P05783	KRT18	Q9UBS0	RPS6KB2	S110	R107K	107	Missense	distal	-3	no	5.859	3.153	EPSD	ICGC;COSMIC	4.103	Loss
AGC_RSK_RSKp70_RPS6KB2_ST	P05783	KRT18	Q9UBS0	RPS6KB2	S110	R106W	106	Missense	distal	-4	no	5.859	5.704	EPSD	ICGC;COSMIC	4.103	Down-regulation
AGC_RSK_RSKp70_RPS6KB2_ST	P05783	KRT18	Q9UBS0	RPS6KB2	S110	T103N	103	Missense	distal	-7	no	5.859	5.964	EPSD	ICGC;COSMIC	4.103	Up-regulation
AGC_RSK_RSKp70_RPS6KB2_ST	P05783	KRT18	Q9UBS0	RPS6KB2	S110	E109D	109	Missense	proximal	-1	no	5.859	5.401	EPSD	ICGC;COSMIC	4.103	Down-regulation
AGC_RSK_RSKp70_RPS6KB2_ST	P05783	KRT18	Q9UBS0	RPS6KB2	S110	R113L	113	Missense	distal	3	no	5.859	5.920	EPSD	ICGC;COSMIC	4.103	Up-regulation
AGC_RSK_RSKp70_RPS6KB2_ST	P05783	KRT18	Q9UBS0	RPS6KB2	S127	K131T	131	Missense	distal	4	no	6.467	6.562	EPSD	ICGC;COSMIC	4.103	Up-regulation
AGC_RSK_RSKp70_RPS6KB2_ST	P05783	KRT18	Q9UBS0	RPS6KB2	S127	Q122P	122	Missense	distal	-5	no	6.467	6.433	EPSD	ICGC;COSMIC	4.103	Down-regulation
AGC_RSK_RSKp70_RPS6KB2_ST	P05783	KRT18	Q9UBS0	RPS6KB2	S127	V123D	123	Missense	distal	-4	no	6.467	6.560	EPSD	ICGC;COSMIC	4.103	Up-regulation
AGC_RSK_RSKp70_RPS6KB2_ST	P05783	KRT18	Q9UBS0	RPS6KB2	S127	P121H	121	Missense	distal	-6	no	6.467	6.419	EPSD	ICGC;COSMIC	4.103	Down-regulation
AGC_RSK_RSKp70_RPS6KB2_ST	O00418	EEF2K	Q9UBS0	RPS6KB2	S61	S66R	66	Missense	distal	5	no	4.142	4.256	EPSD	ICGC	4.103	Up-regulation
AGC_RSK_RSKp70_RPS6KB2_ST	O00418	EEF2K	Q9UBS0	RPS6KB2	S71	P75A	75	Missense	distal	4	no	5.698	5.678	EPSD	ICGC;COSMIC	4.103	Down-regulation
AGC_RSK_RSKp70_RPS6KB2_ST	O00418	EEF2K	Q9UBS0	RPS6KB2	S71	P75L	75	Missense	distal	4	no	5.698	5.723	EPSD	ICGC;COSMIC	4.103	Up-regulation
AGC_RSK_RSKp70_RPS6KB2_ST	O00418	EEF2K	Q9UBS0	RPS6KB2	S71	S71F	71	Missense	central	0	yes	5.698	0.000	EPSD	ICGC;COSMIC	4.103	Loss
AGC_RSK_RSKp70_RPS6KB2_ST	O00418	EEF2K	Q9UBS0	RPS6KB2	S71	S66R	66	Missense	distal	-5	no	5.698	5.885	EPSD	ICGC	4.103	Up-regulation
AGC_RSK_RSKp70_RPS6KB2_ST	O00418	EEF2K	Q9UBS0	RPS6KB2	S243	R247H	247	Missense	distal	4	no	4.356	4.388	EPSD	ICGC;COSMIC	4.103	Up-regulation
AGC_RSK_RSKp70_RPS6KB2_ST	O00418	EEF2K	Q9UBS0	RPS6KB2	S243	N242S	242	Missense	proximal	-1	no	4.356	5.140	EPSD	ICGC;COSMIC	4.103	Up-regulation
AGC_RSK_RSKp70_RPS6KB2_ST	O00418	EEF2K	Q9UBS0	RPS6KB2	S243	D248N	248	Missense	distal	5	no	4.356	4.361	EPSD	ICGC	4.103	Up-regulation
AGC_RSK_RSKp70_RPS6KB2_ST	O00418	EEF2K	Q9UBS0	RPS6KB2	S243	Y236C	236	Missense	distal	-7	no	4.356	4.369	EPSD	ICGC;COSMIC	4.103	Up-regulation
AGC_RSK_RSKp70_RPS6KB2_ST	O00418	EEF2K	Q9UBS0	RPS6KB2	S243	S243Y	243	Missense	central	0	yes	4.356	0.000	EPSD	ICGC;COSMIC	4.103	Loss
AGC_RSK_RSKp70_RPS6KB2_ST	O00418	EEF2K	Q9UBS0	RPS6KB2	T364	Q361R	361	Missense	distal	-3	no	1.693	6.463	EPSD	ICGC	4.103	Gain
AGC_RSK_RSKp70_RPS6KB2_ST	O00418	EEF2K	Q9UBS0	RPS6KB2	S366	R369W	369	Missense	distal	3	no	9.928	10.031	PhosphoSitePlus	ICGC	4.103	Up-regulation
AGC_RSK_RSKp70_RPS6KB2_ST	O00418	EEF2K	Q9UBS0	RPS6KB2	S366	Q361R	361	Missense	distal	-5	no	9.928	10.189	PhosphoSitePlus	ICGC	4.103	Up-regulation
AGC_RSK_RSKp70_RPS6KB2_ST	O00418	EEF2K	Q9UBS0	RPS6KB2	S366	P360L	360	Missense	distal	-6	no	9.928	9.914	PhosphoSitePlus	ICGC	4.103	Down-regulation
AGC_RSK_RSKp70_RPS6KB2_ST	P09651	HNRNPA1	Q9UBS0	RPS6KB2	S6	K3N	3	Missense	distal	-3	no	7.662	5.148	EPSD;PhosphoSitePlus	ICGC;COSMIC	4.103	Down-regulation
AGC_RSK_RSKp70_RPS6KB2_ST	P09651	HNRNPA1	Q9UBS0	RPS6KB2	S6	E9K	9	Missense	distal	3	no	7.662	7.577	EPSD;PhosphoSitePlus	ICGC;COSMIC	4.103	Down-regulation
AGC_RSK_RSKp70_RPS6KB2_ST	P09651	HNRNPA1	Q9UBS0	RPS6KB2	S6	Q12H	12	Missense	distal	6	no	7.662	7.624	EPSD;PhosphoSitePlus	ICGC;COSMIC	4.103	Down-regulation
AGC_RSK_RSKp70_RPS6KB2_ST	P09651	HNRNPA1	Q9UBS0	RPS6KB2	S6	S6F	6	Missense	central	0	yes	7.662	0.000	EPSD;PhosphoSitePlus	ICGC;COSMIC	4.103	Loss
AGC_RSK_RSKp70_RPS6KB2_ST	P09651	HNRNPA1	Q9UBS0	RPS6KB2	S91	D94V	94	Missense	distal	3	no	6.596	6.641	EPSD	ICGC;COSMIC	4.103	Up-regulation
AGC_RSK_RSKp70_RPS6KB2_ST	P09651	HNRNPA1	Q9UBS0	RPS6KB2	S91	R88I	88	Missense	distal	-3	no	6.596	1.181	EPSD	ICGC;COSMIC	4.103	Loss
AGC_RSK_RSKp70_RPS6KB2_ST	P09651	HNRNPA1	Q9UBS0	RPS6KB2	S91	S91C	91	Missense	central	0	yes	6.596	0.000	EPSD	ICGC;COSMIC	4.103	Loss
AGC_RSK_RSKp70_RPS6KB2_ST	P09651	HNRNPA1	Q9UBS0	RPS6KB2	S91	R97K	97	Missense	distal	6	no	6.596	6.619	EPSD	ICGC	4.103	Up-regulation
AGC_RSK_RSKp70_RPS6KB2_ST	P09651	HNRNPA1	Q9UBS0	RPS6KB2	S91	A89V	89	Missense	proximal	-2	no	6.596	6.380	EPSD	ICGC	4.103	Down-regulation
AGC_RSK_RSKp70_RPS6KB2_ST	P09651	HNRNPA1	Q9UBS0	RPS6KB2	S95	D94V	94	Missense	proximal	-1	no	6.790	6.545	EPSD	ICGC;COSMIC	4.103	Down-regulation
AGC_RSK_RSKp70_RPS6KB2_ST	P09651	HNRNPA1	Q9UBS0	RPS6KB2	S95	R88I	88	Missense	distal	-7	no	6.790	6.959	EPSD	ICGC;COSMIC	4.103	Up-regulation
AGC_RSK_RSKp70_RPS6KB2_ST	P09651	HNRNPA1	Q9UBS0	RPS6KB2	S95	S91C	91	Missense	distal	-4	no	6.790	6.452	EPSD	ICGC;COSMIC	4.103	Down-regulation
AGC_RSK_RSKp70_RPS6KB2_ST	P09651	HNRNPA1	Q9UBS0	RPS6KB2	S95	R97K	97	Missense	proximal	2	no	6.790	6.875	EPSD	ICGC	4.103	Up-regulation
AGC_RSK_RSKp70_RPS6KB2_ST	P09651	HNRNPA1	Q9UBS0	RPS6KB2	S95	H101N	101	Missense	distal	6	no	6.790	6.763	EPSD	ICGC;COSMIC	4.103	Down-regulation
AGC_RSK_RSKp70_RPS6KB2_ST	P09651	HNRNPA1	Q9UBS0	RPS6KB2	S95	A89V	89	Missense	distal	-6	no	6.790	6.843	EPSD	ICGC	4.103	Up-regulation
AGC_RSK_RSKp70_RPS6KB2_ST	Q6R327	RICTOR	Q9UBS0	RPS6KB2	S21	N19S	19	Missense	proximal	-2	no	6.466	7.425	EPSD	ICGC;COSMIC	4.103	Up-regulation
AGC_RSK_RSKp70_RPS6KB2_ST	Q6R327	RICTOR	Q9UBS0	RPS6KB2	S35	N37K	37	Missense	proximal	2	no	5.932	5.874	EPSD	ICGC	4.103	Down-regulation
AGC_RSK_RSKp70_RPS6KB2_ST	Q6R327	RICTOR	Q9UBS0	RPS6KB2	S383	R380C	380	Missense	distal	-3	no	6.174	0.882	EPSD	ICGC;COSMIC	4.103	Loss
AGC_RSK_RSKp70_RPS6KB2_ST	Q6R327	RICTOR	Q9UBS0	RPS6KB2	S383	P385T	385	Missense	proximal	2	no	6.174	6.078	EPSD	ICGC	4.103	Down-regulation
AGC_RSK_RSKp70_RPS6KB2_ST	Q6R327	RICTOR	Q9UBS0	RPS6KB2	S383	L377F	377	Missense	distal	-6	no	6.174	6.274	EPSD	ICGC	4.103	Up-regulation
AGC_RSK_RSKp70_RPS6KB2_ST	Q6R327	RICTOR	Q9UBS0	RPS6KB2	S383	A381V	381	Missense	proximal	-2	no	6.174	5.958	EPSD	ICGC	4.103	Down-regulation
AGC_RSK_RSKp70_RPS6KB2_ST	Q6R327	RICTOR	Q9UBS0	RPS6KB2	S585	N590K	590	Missense	distal	5	no	4.137	4.118	EPSD	ICGC;COSMIC	4.103	Down-regulation
AGC_RSK_RSKp70_RPS6KB2_ST	Q6R327	RICTOR	Q9UBS0	RPS6KB2	S703	L700R	700	Missense	distal	-3	no	0.183	6.199	EPSD	ICGC;COSMIC	4.103	Gain
AGC_RSK_RSKp70_RPS6KB2_ST	Q6R327	RICTOR	Q9UBS0	RPS6KB2	S810	L809F	809	Missense	proximal	-1	no	7.073	5.148	EPSD	ICGC;COSMIC	4.103	Down-regulation
AGC_RSK_RSKp70_RPS6KB2_ST	Q6R327	RICTOR	Q9UBS0	RPS6KB2	S1035	S1031C	1031	Missense	distal	-4	no	6.417	6.078	EPSD	ICGC;COSMIC;GDSC;CCLE	4.103	Down-regulation
AGC_RSK_RSKp70_RPS6KB2_ST	Q6R327	RICTOR	Q9UBS0	RPS6KB2	S1122	P1115S	1115	Missense	distal	-7	no	5.186	5.016	EPSD	ICGC	4.103	Down-regulation
AGC_RSK_RSKp70_RPS6KB2_ST	Q6R327	RICTOR	Q9UBS0	RPS6KB2	T1198	V1204I	1204	Missense	distal	6	no	4.999	4.997	EPSD	ICGC;COSMIC	4.103	Down-regulation
AGC_RSK_RSKp70_RPS6KB2_ST	Q6R327	RICTOR	Q9UBS0	RPS6KB2	S1217	R1216C	1216	Missense	proximal	-1	no	3.627	4.434	EPSD	ICGC;COSMIC	4.103	Gain
AGC_RSK_RSKp70_RPS6KB2_ST	Q6R327	RICTOR	Q9UBS0	RPS6KB2	S1219	R1216C	1216	Missense	distal	-3	no	8.046	2.753	EPSD	ICGC;COSMIC	4.103	Loss
AGC_RSK_RSKp70_RPS6KB2_ST	Q6R327	RICTOR	Q9UBS0	RPS6KB2	S1302	L1296P	1296	Missense	distal	-6	no	5.813	5.827	EPSD	ICGC;COSMIC	4.103	Up-regulation
TK_Src_SrcA_FGR_Y	P09917	ALOX5	P09769	FGR	Y75	R73C	73	Missense	proximal	-2	no	7.615	7.503	EPSD	ICGC;COSMIC;GDSC;CCLE	5.114	Down-regulation
TK_Src_SrcA_FGR_Y	Q05397	PTK2	P09769	FGR	Y441	D435N	435	Missense	distal	-6	no	5.191	5.129	EPSD	ICGC;COSMIC	5.114	Down-regulation
TK_Src_SrcA_FGR_Y	Q05397	PTK2	P09769	FGR	Y441	H437N	437	Missense	distal	-4	no	5.191	5.920	EPSD	ICGC	5.114	Up-regulation
TK_Src_SrcA_FGR_Y	Q9UHD2	TBK1	P09769	FGR	Y340	I346M	346	Missense	distal	6	no	5.205	4.814	EPSD	ICGC	5.114	Loss
TK_Src_SrcA_FGR_Y	Q9UHD2	TBK1	P09769	FGR	Y340	Q342H	342	Missense	proximal	2	no	5.205	5.835	EPSD	ICGC;COSMIC	5.114	Up-regulation
TK_Src_SrcA_FGR_Y	Q9UHD2	TBK1	P09769	FGR	Y394	T389I	389	Missense	distal	-5	no	10.242	10.270	EPSD;PhosphoSitePlus	ICGC;COSMIC	5.114	Up-regulation
TK_Src_SrcA_FGR_Y	Q9UHD2	TBK1	P09769	FGR	Y394	P400S	400	Missense	distal	6	no	10.242	9.755	EPSD;PhosphoSitePlus	ICGC;COSMIC	5.114	Down-regulation
TK_Src_SrcA_FGR_Y	Q9UHD2	TBK1	P09769	FGR	Y394	P400H	400	Missense	distal	6	no	10.242	10.113	EPSD;PhosphoSitePlus	ICGC;COSMIC	5.114	Down-regulation
TK_Src_SrcA_FGR_Y	Q9UHD2	TBK1	P09769	FGR	Y577	I582F	582	Missense	distal	5	no	7.400	7.801	EPSD	ICGC;COSMIC	5.114	Up-regulation
TK_Src_SrcA_FGR_Y	Q9UHD2	TBK1	P09769	FGR	Y592	A594S	594	Missense	proximal	2	no	4.916	6.172	EPSD	ICGC	5.114	Gain
TK_Src_SRM_Y	Q13882	PTK6	Q13882	PTK6	Y447	L441I	441	Missense	distal	-6	no	3.022	3.058	PhosphoSitePlus;EPSD	ICGC	1.179	Up-regulation
TK_Src_SRM_Y	Q13882	PTK6	Q13882	PTK6	Y447	F444V	444	Missense	distal	-3	no	3.022	3.103	PhosphoSitePlus;EPSD	ICGC	1.179	Up-regulation
TK_Src_SRM_PTK6_Y	Q13882	PTK6	Q13882	PTK6	Y13	W17L	17	Missense	distal	4	no	21.269	20.582	EPSD	ICGC;COSMIC	13.984	Down-regulation
TK_Src_SRM_PTK6_Y	Q13882	PTK6	Q13882	PTK6	Y13	K20T	20	Missense	distal	7	no	21.269	21.548	EPSD	ICGC;COSMIC	13.984	Up-regulation
TK_Src_SRM_PTK6_Y	Q13882	PTK6	Q13882	PTK6	Y114	D113N	113	Missense	proximal	-1	no	19.659	19.851	EPSD	ICGC;COSMIC	13.984	Up-regulation
TK_Src_SRM_PTK6_Y	Q13882	PTK6	Q13882	PTK6	Y447	L441I	441	Missense	distal	-6	no	39.672	40.230	PhosphoSitePlus;EPSD	ICGC	13.984	Up-regulation
TK_Src_SRM_PTK6_Y	Q13882	PTK6	Q13882	PTK6	Y447	F444V	444	Missense	distal	-3	no	39.672	41.091	PhosphoSitePlus;EPSD	ICGC	13.984	Up-regulation
TK_Src_SRM_Y	P35222	CTNNB1	Q13882	PTK6	Y331	T332N	332	Missense	proximal	1	no	2.092	2.069	EPSD;PhosphoSitePlus	ICGC;COSMIC	1.179	Down-regulation
TK_Src_SRM_Y	P35222	CTNNB1	Q13882	PTK6	Y333	T332N	332	Missense	proximal	-1	no	1.300	1.294	EPSD;PhosphoSitePlus	ICGC;COSMIC	1.179	Down-regulation
TK_Src_SRM_PTK6_Y	P35222	CTNNB1	Q13882	PTK6	Y331	T332N	332	Missense	proximal	1	no	29.435	28.981	EPSD;PhosphoSitePlus	ICGC;COSMIC	13.984	Down-regulation
TK_Src_SRM_PTK6_Y	P35222	CTNNB1	Q13882	PTK6	Y333	T332N	332	Missense	proximal	-1	no	26.739	26.785	EPSD;PhosphoSitePlus	ICGC;COSMIC	13.984	Up-regulation
TK_Src_SRM_Y	Q9UGK3	STAP2	Q13882	PTK6	Y21	K14N	14	Missense	distal	-7	no	1.807	1.795	EPSD	ICGC;COSMIC	1.179	Down-regulation
TK_Src_SRM_Y	Q9UGK3	STAP2	Q13882	PTK6	Y250	E248G	248	Missense	proximal	-2	no	1.628	1.530	PhosphoSitePlus	ICGC;COSMIC	1.179	Down-regulation
TK_Src_SRM_Y	Q9UGK3	STAP2	Q13882	PTK6	Y250	Y256F	256	Missense	distal	6	no	1.628	1.689	PhosphoSitePlus	ICGC	1.179	Up-regulation
TK_Src_SRM_Y	Q9UGK3	STAP2	Q13882	PTK6	Y250	K252N	252	Missense	proximal	2	no	1.628	1.631	PhosphoSitePlus	ICGC;COSMIC	1.179	Up-regulation
TK_Src_SRM_Y	Q9UGK3	STAP2	Q13882	PTK6	Y250	L245M	245	Missense	distal	-5	no	1.628	1.673	PhosphoSitePlus	ICGC	1.179	Up-regulation
TK_Src_SRM_Y	Q9UGK3	STAP2	Q13882	PTK6	Y310	N309T	309	Missense	proximal	-1	no	1.684	1.690	EPSD	ICGC;COSMIC	1.179	Up-regulation
TK_Src_SRM_PTK6_Y	Q9UGK3	STAP2	Q13882	PTK6	Y21	K14N	14	Missense	distal	-7	no	18.605	18.794	EPSD	ICGC;COSMIC	13.984	Up-regulation
TK_Src_SRM_PTK6_Y	Q9UGK3	STAP2	Q13882	PTK6	Y250	E248G	248	Missense	proximal	-2	no	28.373	27.447	PhosphoSitePlus	ICGC;COSMIC	13.984	Down-regulation
TK_Src_SRM_PTK6_Y	Q9UGK3	STAP2	Q13882	PTK6	Y250	Y256F	256	Missense	distal	6	no	28.373	30.188	PhosphoSitePlus	ICGC	13.984	Up-regulation
TK_Src_SRM_PTK6_Y	Q9UGK3	STAP2	Q13882	PTK6	Y250	K252N	252	Missense	proximal	2	no	28.373	27.502	PhosphoSitePlus	ICGC;COSMIC	13.984	Down-regulation
TK_Src_SRM_PTK6_Y	Q9UGK3	STAP2	Q13882	PTK6	Y250	L245M	245	Missense	distal	-5	no	28.373	28.550	PhosphoSitePlus	ICGC	13.984	Up-regulation
TK_Src_SRM_PTK6_Y	Q9UGK3	STAP2	Q13882	PTK6	Y310	N309T	309	Missense	proximal	-1	no	16.841	16.795	EPSD	ICGC;COSMIC	13.984	Down-regulation
TK_Src_SRM_Y	P56945	BCAR1	Q13882	PTK6	Y222	P229H	229	Missense	distal	7	no	1.142	1.196	EPSD	ICGC;COSMIC	1.179	Gain
TK_Src_SRM_Y	P56945	BCAR1	Q13882	PTK6	Y234	P229H	229	Missense	distal	-5	no	1.255	1.494	EPSD	ICGC;COSMIC	1.179	Up-regulation
TK_Src_SRM_PTK6_Y	P56945	BCAR1	Q13882	PTK6	Y234	P229H	229	Missense	distal	-5	no	16.323	19.119	EPSD	ICGC;COSMIC	13.984	Up-regulation
TK_Src_SRM_PTK6_Y	Q96P48	ARAP1	Q13882	PTK6	Y231	D228V	228	Missense	distal	-3	no	16.940	14.809	PhosphoSitePlus	ICGC;COSMIC	13.984	Down-regulation
TK_Src_SRM_PTK6_Y	Q96P48	ARAP1	Q13882	PTK6	Y231	E225V	225	Missense	distal	-6	no	16.940	17.655	PhosphoSitePlus	ICGC	13.984	Up-regulation
TK_Src_SRM_Y	P31749	AKT1	Q13882	PTK6	Y326	D323G	323	Missense	distal	-3	no	2.808	2.662	PhosphoSitePlus;EPSD	ICGC;COSMIC	1.179	Down-regulation
TK_Src_SRM_Y	P31749	AKT1	Q13882	PTK6	Y326	A329E	329	Missense	distal	3	no	2.808	3.140	PhosphoSitePlus;EPSD	ICGC	1.179	Up-regulation
TK_Src_SRM_Y	P31749	AKT1	Q13882	PTK6	Y326	D325E	325	Missense	proximal	-1	no	2.808	2.852	PhosphoSitePlus;EPSD	ICGC	1.179	Up-regulation
TK_Src_SRM_PTK6_Y	P31749	AKT1	Q13882	PTK6	Y326	D323G	323	Missense	distal	-3	no	29.725	27.893	PhosphoSitePlus;EPSD	ICGC;COSMIC	13.984	Down-regulation
TK_Src_SRM_PTK6_Y	P31749	AKT1	Q13882	PTK6	Y326	A329E	329	Missense	distal	3	no	29.725	34.152	PhosphoSitePlus;EPSD	ICGC	13.984	Up-regulation
TK_Src_SRM_PTK6_Y	P31749	AKT1	Q13882	PTK6	Y326	D325E	325	Missense	proximal	-1	no	29.725	29.873	PhosphoSitePlus;EPSD	ICGC	13.984	Up-regulation
TK_Src_SRM_Y	P51692	STAT5B	Q13882	PTK6	Y699	A695S	695	Missense	distal	-4	no	1.817	1.805	PhosphoSitePlus	ICGC;COSMIC	1.179	Down-regulation
TK_Src_SRM_PTK6_Y	P51692	STAT5B	Q13882	PTK6	Y683	P687S	687	Missense	distal	4	no	18.711	18.999	EPSD	ICGC;COSMIC	13.984	Up-regulation
TK_Src_SRM_PTK6_Y	P51692	STAT5B	Q13882	PTK6	Y699	A695S	695	Missense	distal	-4	no	28.331	27.726	PhosphoSitePlus	ICGC;COSMIC	13.984	Down-regulation
TK_Src_SRM_Y	Q13017	ARHGAP5	Q13882	PTK6	Y587	R583L	583	Missense	distal	-4	no	1.213	1.170	EPSD	ICGC	1.179	Loss
TK_Src_SRM_Y	Q13017	ARHGAP5	Q13882	PTK6	Y587	R583S	583	Missense	distal	-4	no	1.213	1.113	EPSD	ICGC;COSMIC	1.179	Loss
TK_Src_SRM_Y	Q13017	ARHGAP5	Q13882	PTK6	Y1091	M1085V	1085	Missense	distal	-6	no	2.071	2.076	EPSD	ICGC;COSMIC	1.179	Up-regulation
TK_Src_SRM_Y	Q13017	ARHGAP5	Q13882	PTK6	Y1091	P1087L	1087	Missense	distal	-4	no	2.071	2.188	EPSD	ICGC;COSMIC	1.179	Up-regulation
TK_Src_SRM_Y	Q13017	ARHGAP5	Q13882	PTK6	Y1109	E1107D	1107	Missense	proximal	-2	no	2.493	2.463	PhosphoSitePlus	ICGC;COSMIC	1.179	Down-regulation
TK_Src_SRM_Y	Q13017	ARHGAP5	Q13882	PTK6	Y1109	S1105F	1105	Missense	distal	-4	no	2.493	2.598	PhosphoSitePlus	ICGC;COSMIC	1.179	Up-regulation
TK_Src_SRM_PTK6_Y	Q13017	ARHGAP5	Q13882	PTK6	Y1091	M1085V	1085	Missense	distal	-6	no	23.828	24.470	EPSD	ICGC;COSMIC	13.984	Up-regulation
TK_Src_SRM_PTK6_Y	Q13017	ARHGAP5	Q13882	PTK6	Y1091	P1087L	1087	Missense	distal	-4	no	23.828	25.162	EPSD	ICGC;COSMIC	13.984	Up-regulation
TK_Src_SRM_PTK6_Y	Q13017	ARHGAP5	Q13882	PTK6	Y1109	E1107D	1107	Missense	proximal	-2	no	33.538	33.659	PhosphoSitePlus	ICGC;COSMIC	13.984	Up-regulation
TK_Src_SRM_PTK6_Y	Q13017	ARHGAP5	Q13882	PTK6	Y1109	S1105F	1105	Missense	distal	-4	no	33.538	35.243	PhosphoSitePlus	ICGC;COSMIC	13.984	Up-regulation
Other_ULK_ULK_ULK1_ST	Q16543	CDC37	O75385	ULK1	S140	T136M	136	Missense	distal	-4	no	34.433	33.795	EPSD	ICGC;COSMIC	29.179	Down-regulation
Other_ULK_ULK_ULK1_ST	Q16543	CDC37	O75385	ULK1	S140	E138D	138	Missense	proximal	-2	no	34.433	36.678	EPSD	ICGC	29.179	Up-regulation
Other_ULK_ULK_ULK1_ST	Q8N122	RPTOR	O75385	ULK1	S8	M5I	5	Missense	distal	-3	no	47.595	35.897	EPSD	ICGC;COSMIC	29.179	Down-regulation
Other_ULK_ULK_ULK1_ST	Q8N122	RPTOR	O75385	ULK1	S8	G12V	12	Missense	distal	4	no	47.595	46.605	EPSD	ICGC	29.179	Down-regulation
Other_ULK_ULK_ULK1_ST	Q8N122	RPTOR	O75385	ULK1	S8	G14R	14	Missense	distal	6	no	47.595	46.725	EPSD	ICGC;COSMIC	29.179	Down-regulation
Other_ULK_ULK_ULK1_ST	Q8N122	RPTOR	O75385	ULK1	S48	S48I	48	Missense	central	0	yes	32.222	0.000	EPSD	ICGC	29.179	Loss
Other_ULK_ULK_ULK1_ST	Q8N122	RPTOR	O75385	ULK1	S48	A46S	46	Missense	proximal	-2	no	32.222	37.744	EPSD	ICGC	29.179	Up-regulation
Other_ULK_ULK_ULK1_ST	Q8N122	RPTOR	O75385	ULK1	S792	D785Y	785	Missense	distal	-7	no	40.283	38.584	EPSD;PhosphoSitePlus	ICGC	29.179	Down-regulation
Other_ULK_ULK_ULK1_ST	Q8N122	RPTOR	O75385	ULK1	S855	T853M	853	Missense	proximal	-2	no	37.170	34.433	PhosphoSitePlus;EPSD	ICGC;COSMIC	29.179	Down-regulation
Other_ULK_ULK_ULK1_ST	Q8N122	RPTOR	O75385	ULK1	S859	T853M	853	Missense	distal	-6	no	49.120	48.920	EPSD;PhosphoSitePlus	ICGC;COSMIC	29.179	Down-regulation
Other_ULK_ULK_ULK1_ST	Q7Z3C6	ATG9A	O75385	ULK1	S741	S738C	738	Missense	distal	-3	no	23.556	31.722	EPSD	ICGC;COSMIC	29.179	Gain
Other_ULK_ULK_ULK1_ST	P09467	FBP1	O75385	ULK1	S63	T64N	64	Missense	proximal	1	no	41.623	41.613	EPSD;PhosphoSitePlus	ICGC;COSMIC	29.179	Down-regulation
Other_ULK_ULK_ULK1_ST	P09467	FBP1	O75385	ULK1	T256	M249I	249	Missense	distal	-7	no	30.963	29.829	EPSD	ICGC;COSMIC	29.179	Down-regulation
Other_ULK_ULK_ULK1_ST	P09467	FBP1	O75385	ULK1	T256	L257V	257	Missense	proximal	1	no	30.963	30.940	EPSD	ICGC	29.179	Down-regulation
Other_ULK_ULK_ULK1_ST	P09467	FBP1	O75385	ULK1	T256	L257M	257	Missense	proximal	1	no	30.963	30.984	EPSD	ICGC	29.179	Up-regulation
Other_ULK_ULK_ULK1_ST	P09467	FBP1	O75385	ULK1	T256	G261E	261	Missense	distal	5	no	30.963	31.097	EPSD	ICGC	29.179	Up-regulation
Other_ULK_ULK_ULK1_ST	P09467	FBP1	O75385	ULK1	T256	T256A	256	Missense	central	0	yes	30.963	0.000	EPSD	ICGC	29.179	Loss
Other_ULK_ULK_ULK1_ST	P09467	FBP1	O75385	ULK1	T256	G261W	261	Missense	distal	5	no	30.963	33.588	EPSD	ICGC;COSMIC	29.179	Up-regulation
Other_ULK_ULK_ULK1_ST	P09467	FBP1	O75385	ULK1	T298	T297A	297	Missense	proximal	-1	no	32.432	32.422	EPSD	ICGC;COSMIC	29.179	Down-regulation
Other_ULK_ULK_ULK1_ST	P09467	FBP1	O75385	ULK1	T298	D305Y	305	Missense	distal	7	no	32.432	33.251	EPSD	ICGC	29.179	Up-regulation
Other_ULK_ULK_ULK1_ST	P09467	FBP1	O75385	ULK1	T298	A302D	302	Missense	distal	4	no	32.432	33.194	EPSD	ICGC	29.179	Up-regulation
Other_ULK_ULK_ULK1_ST	P08235	NR3C2	O75385	ULK1	S238	T233A	233	Missense	distal	-5	no	38.146	36.444	EPSD	ICGC	29.179	Down-regulation
Other_ULK_ULK_ULK1_ST	P08235	NR3C2	O75385	ULK1	S266	S263I	263	Missense	distal	-3	no	27.037	38.324	EPSD	ICGC;COSMIC	29.179	Gain
Other_ULK_ULK_ULK1_ST	Q8TEV9	SMCR8	O75385	ULK1	S238	L236P	236	Missense	proximal	-2	no	24.825	29.508	EPSD	ICGC	29.179	Gain
Other_ULK_ULK_ULK1_ST	Q8TEV9	SMCR8	O75385	ULK1	S400	D396E	396	Missense	distal	-4	no	42.706	39.914	PhosphoSitePlus;EPSD	ICGC;COSMIC	29.179	Down-regulation
Other_ULK_ULK_ULK1_ST	Q8TEV9	SMCR8	O75385	ULK1	S465	G469C	469	Missense	distal	4	no	41.519	40.456	EPSD	ICGC;COSMIC	29.179	Down-regulation
Other_ULK_ULK_ULK1_ST	Q8TEV9	SMCR8	O75385	ULK1	S465	E470K	470	Missense	distal	5	no	41.519	42.429	EPSD	ICGC;COSMIC	29.179	Up-regulation
Other_ULK_ULK_ULK1_ST	Q8TEV9	SMCR8	O75385	ULK1	S465	I466F	466	Missense	proximal	1	no	41.519	41.501	EPSD	ICGC	29.179	Down-regulation
Other_ULK_ULK_ULK1_ST	Q8TEV9	SMCR8	O75385	ULK1	S465	D459N	459	Missense	distal	-6	no	41.519	40.878	EPSD	ICGC	29.179	Down-regulation
Other_ULK_ULK_ULK1_ST	Q8TEV9	SMCR8	O75385	ULK1	S492	Q490L	490	Missense	proximal	-2	no	37.994	32.065	EPSD;PhosphoSitePlus	ICGC;COSMIC	29.179	Down-regulation
Other_ULK_ULK_ULK1_ST	Q8TEV9	SMCR8	O75385	ULK1	S492	P496Q	496	Missense	distal	4	no	37.994	38.278	EPSD;PhosphoSitePlus	ICGC;COSMIC	29.179	Up-regulation
Other_ULK_ULK_ULK1_ST	Q8TEV9	SMCR8	O75385	ULK1	S492	A491S	491	Missense	proximal	-1	no	37.994	38.818	EPSD;PhosphoSitePlus	ICGC;COSMIC	29.179	Up-regulation
Other_ULK_ULK_ULK1_ST	Q8TEV9	SMCR8	O75385	ULK1	S498	P496Q	496	Missense	proximal	-2	no	33.080	34.326	EPSD	ICGC;COSMIC	29.179	Up-regulation
Other_ULK_ULK_ULK1_ST	Q8TEV9	SMCR8	O75385	ULK1	S498	A491S	491	Missense	distal	-7	no	33.080	35.375	EPSD	ICGC;COSMIC	29.179	Up-regulation
Other_ULK_ULK_ULK1_ST	Q8TEV9	SMCR8	O75385	ULK1	S562	R556H	556	Missense	distal	-6	no	43.467	46.189	EPSD;PhosphoSitePlus	ICGC;COSMIC	29.179	Up-regulation
Other_ULK_ULK_ULK1_ST	Q8TEV9	SMCR8	O75385	ULK1	S562	R556C	556	Missense	distal	-6	no	43.467	40.285	EPSD;PhosphoSitePlus	ICGC	29.179	Down-regulation
Other_ULK_ULK_ULK1_ST	Q8TEV9	SMCR8	O75385	ULK1	S606	D609Y	609	Missense	distal	3	no	32.965	33.869	EPSD	ICGC	29.179	Up-regulation
Other_ULK_ULK_ULK1_ST	Q8TEV9	SMCR8	O75385	ULK1	S606	E608D	608	Missense	proximal	2	no	32.965	32.885	EPSD	ICGC	29.179	Down-regulation
Other_ULK_ULK_ULK1_ST	Q8TEV9	SMCR8	O75385	ULK1	S643	N636S	636	Missense	distal	-7	no	33.692	35.190	EPSD	ICGC;COSMIC	29.179	Up-regulation
Other_ULK_ULK_ULK1_ST	Q8TEV9	SMCR8	O75385	ULK1	S643	P648L	648	Missense	distal	5	no	33.692	33.461	EPSD	ICGC;COSMIC	29.179	Down-regulation
Other_ULK_ULK_ULK1_ST	Q8TEV9	SMCR8	O75385	ULK1	T666	S664T	664	Missense	proximal	-2	no	40.511	35.396	EPSD;PhosphoSitePlus	ICGC;COSMIC	29.179	Down-regulation
Other_ULK_ULK_ULK1_ST	Q8TEV9	SMCR8	O75385	ULK1	S691	I689M	689	Missense	proximal	-2	no	28.617	31.875	EPSD	ICGC	29.179	Gain
Other_ULK_ULK_ULK1_ST	Q8TEV9	SMCR8	O75385	ULK1	S691	P690S	690	Missense	proximal	-1	no	28.617	29.212	EPSD	ICGC	29.179	Gain
Other_ULK_ULK_ULK1_ST	O75143	ATG13	O75385	ULK1	S334	A340V	340	Missense	distal	6	no	33.683	33.145	EPSD	ICGC;COSMIC	29.179	Down-regulation
Other_ULK_ULK_ULK1_ST	O75143	ATG13	O75385	ULK1	S334	H338Q	338	Missense	distal	4	no	33.683	32.311	EPSD	ICGC;COSMIC	29.179	Down-regulation
Other_ULK_ULK_ULK1_ST	O75143	ATG13	O75385	ULK1	S355	S355I	355	Missense	central	0	yes	47.502	0.000	PhosphoSitePlus;EPSD	ICGC;COSMIC	29.179	Loss
Other_ULK_ULK_ULK1_ST	O75143	ATG13	O75385	ULK1	S355	R359L	359	Missense	distal	4	no	47.502	47.000	PhosphoSitePlus;EPSD	ICGC;COSMIC	29.179	Down-regulation
Other_ULK_ULK_ULK1_ST	O75143	ATG13	O75385	ULK1	S355	N354H	354	Missense	proximal	-1	no	47.502	47.973	PhosphoSitePlus;EPSD	ICGC	29.179	Up-regulation
Other_ULK_ULK_ULK1_ST	O75143	ATG13	O75385	ULK1	S416	P413L	413	Missense	distal	-3	no	26.464	36.195	EPSD	ICGC;COSMIC	29.179	Gain
Other_ULK_ULK_ULK1_ST	P08237	PFKM	O75385	ULK1	S74	M75I	75	Missense	proximal	1	no	43.681	43.647	PhosphoSitePlus;EPSD	ICGC;COSMIC	29.179	Down-regulation
Other_ULK_ULK_ULK1_ST	P08237	PFKM	O75385	ULK1	S74	L77I	77	Missense	distal	3	no	43.681	44.594	PhosphoSitePlus;EPSD	ICGC;COSMIC	29.179	Up-regulation
Other_ULK_ULK_ULK1_ST	P08237	PFKM	O75385	ULK1	S74	S74L	74	Missense	central	0	yes	43.681	0.000	PhosphoSitePlus;EPSD	ICGC;COSMIC;GDSC;CCLE	29.179	Loss
Other_ULK_ULK_ULK1_ST	Q15437	SEC23B	O75385	ULK1	S150	A146S	146	Missense	distal	-4	no	31.701	33.803	EPSD	ICGC	29.179	Up-regulation
Other_ULK_ULK_ULK1_ST	Q15437	SEC23B	O75385	ULK1	S154	P160S	160	Missense	distal	6	no	36.350	36.821	EPSD	ICGC	29.179	Up-regulation
Other_ULK_ULK_ULK1_ST	Q15437	SEC23B	O75385	ULK1	T407	S413T	413	Missense	distal	6	no	34.319	33.862	EPSD	ICGC;COSMIC	29.179	Down-regulation
Other_ULK_ULK_ULK1_ST	Q15437	SEC23B	O75385	ULK1	T407	A403V	403	Missense	distal	-4	no	34.319	32.091	EPSD	ICGC	29.179	Down-regulation
Other_ULK_ULK_ULK1_ST	Q14457	BECN1	O75385	ULK1	S15	Q13R	13	Missense	proximal	-2	no	44.157	40.488	EPSD;PhosphoSitePlus	ICGC;COSMIC	29.179	Down-regulation
Other_ULK_ULK_ULK1_ST	Q14457	BECN1	O75385	ULK1	S15	M12I	12	Missense	distal	-3	no	44.157	32.460	EPSD;PhosphoSitePlus	ICGC;COSMIC	29.179	Down-regulation
Other_ULK_ULK_ULK1_ST	Q14457	BECN1	O75385	ULK1	S15	R20H	20	Missense	distal	5	no	44.157	44.108	EPSD;PhosphoSitePlus	ICGC;COSMIC	29.179	Down-regulation
Other_ULK_ULK_ULK1_ST	Q14457	BECN1	O75385	ULK1	S30	P24T	24	Missense	distal	-6	no	28.906	31.779	PhosphoSitePlus;EPSD	ICGC	29.179	Gain
Other_ULK_ULK_ULK1_ST	Q14457	BECN1	O75385	ULK1	S30	P24L	24	Missense	distal	-6	no	28.906	30.465	PhosphoSitePlus;EPSD	ICGC	29.179	Gain
Other_ULK_ULK_ULK1_ST	Q14457	BECN1	O75385	ULK1	S64	P68T	68	Missense	distal	4	no	33.444	34.182	EPSD	ICGC;COSMIC	29.179	Up-regulation
Other_ULK_ULK_ULK1_ST	Q14457	BECN1	O75385	ULK1	T91	P85Q	85	Missense	distal	-6	no	25.951	29.764	EPSD	ICGC	29.179	Gain
Other_ULK_ULK_ULK1_ST	Q14457	BECN1	O75385	ULK1	S234	Q240K	240	Missense	distal	6	no	31.052	30.681	EPSD	ICGC	29.179	Down-regulation
Other_ULK_ULK_ULK1_ST	Q14457	BECN1	O75385	ULK1	S234	Q230H	230	Missense	distal	-4	no	31.052	33.624	EPSD	ICGC;COSMIC	29.179	Up-regulation
Other_ULK_ULK_ULK1_ST	Q14457	BECN1	O75385	ULK1	S414	I415M	415	Missense	proximal	1	no	29.833	29.866	EPSD	ICGC	29.179	Up-regulation
Other_ULK_ULK_ULK1_ST	P06733	ENO1	O75385	ULK1	T100	G107S	107	Missense	distal	7	no	34.501	34.303	EPSD	ICGC	29.179	Down-regulation
Other_ULK_ULK_ULK1_ST	P06733	ENO1	O75385	ULK1	S104	G107S	107	Missense	distal	3	no	32.418	31.069	EPSD	ICGC	29.179	Down-regulation
Other_ULK_ULK_ULK1_ST	P06733	ENO1	O75385	ULK1	S104	A108V	108	Missense	distal	4	no	32.418	31.743	EPSD	ICGC;COSMIC;CCLE	29.179	Down-regulation
Other_ULK_ULK_ULK1_ST	P06733	ENO1	O75385	ULK1	S115	A108V	108	Missense	distal	-7	no	42.919	41.951	PhosphoSitePlus;EPSD	ICGC;COSMIC;CCLE	29.179	Down-regulation
Other_ULK_ULK_ULK1_ST	P06733	ENO1	O75385	ULK1	S282	D286N	286	Missense	distal	4	no	39.464	38.952	EPSD;PhosphoSitePlus	ICGC;COSMIC	29.179	Down-regulation
Other_ULK_ULK_ULK1_ST	P06733	ENO1	O75385	ULK1	S282	K285N	285	Missense	distal	3	no	39.464	36.414	EPSD;PhosphoSitePlus	ICGC;COSMIC	29.179	Down-regulation
Other_ULK_ULK_ULK1_ST	P06733	ENO1	O75385	ULK1	S282	P288Q	288	Missense	distal	6	no	39.464	39.683	EPSD;PhosphoSitePlus	ICGC;COSMIC	29.179	Up-regulation
Other_ULK_ULK_ULK1_ST	P06733	ENO1	O75385	ULK1	S353	E352K	352	Missense	proximal	-1	no	34.369	33.519	EPSD	ICGC;COSMIC	29.179	Down-regulation
Other_ULK_ULK_ULK1_ST	P06733	ENO1	O75385	ULK1	S353	Q346H	346	Missense	distal	-7	no	34.369	34.688	EPSD	ICGC;COSMIC	29.179	Up-regulation
Other_ULK_ULK_ULK1_ST	Q8NFG4	FLCN	O75385	ULK1	S62	A60E	60	Missense	proximal	-2	no	32.991	32.305	EPSD	ICGC	29.179	Down-regulation
Other_ULK_ULK_ULK1_ST	Q8NFG4	FLCN	O75385	ULK1	S62	H61R	61	Missense	proximal	-1	no	32.991	32.768	EPSD	ICGC;COSMIC	29.179	Down-regulation
Other_ULK_ULK_ULK1_ST	Q8NFG4	FLCN	O75385	ULK1	S298	A304D	304	Missense	distal	6	no	34.105	34.338	EPSD	ICGC	29.179	Up-regulation
Other_ULK_ULK_ULK1_ST	Q8NFG4	FLCN	O75385	ULK1	S298	A304S	304	Missense	distal	6	no	34.105	34.351	EPSD	ICGC	29.179	Up-regulation
Other_ULK_ULK_ULK1_ST	Q8NFG4	FLCN	O75385	ULK1	T323	E321D	321	Missense	proximal	-2	no	27.790	30.036	EPSD	ICGC;COSMIC	29.179	Gain
Other_ULK_ULK_ULK1_ST	Q8NFG4	FLCN	O75385	ULK1	S329	P326L	326	Missense	distal	-3	no	20.450	30.180	EPSD	ICGC	29.179	Gain
Other_ULK_ULK_ULK1_ST	Q8IVP5	FUNDC1	O75385	ULK1	S17	V20G	20	Missense	distal	3	no	38.087	35.496	PhosphoSitePlus	ICGC;COSMIC	29.179	Down-regulation
Other_ULK_ULK_ULK1_ST	P19367	HK1	O75385	ULK1	S32	R30W	30	Missense	proximal	-2	no	31.657	27.489	EPSD	ICGC;COSMIC;CCLE	29.179	Loss
Other_ULK_ULK_ULK1_ST	P19367	HK1	O75385	ULK1	S32	A28V	28	Missense	distal	-4	no	31.657	29.429	EPSD	ICGC;COSMIC	29.179	Down-regulation
Other_ULK_ULK_ULK1_ST	P19367	HK1	O75385	ULK1	S32	R30H	30	Missense	proximal	-2	no	31.657	38.228	EPSD	ICGC;COSMIC	29.179	Up-regulation
Other_ULK_ULK_ULK1_ST	P19367	HK1	O75385	ULK1	S32	Y27H	27	Missense	distal	-5	no	31.657	36.787	EPSD	ICGC	29.179	Up-regulation
Other_ULK_ULK_ULK1_ST	P19367	HK1	O75385	ULK1	S124	G123R	123	Missense	proximal	-1	no	33.000	32.757	EPSD;PhosphoSitePlus	ICGC;COSMIC	29.179	Down-regulation
Other_ULK_ULK_ULK1_ST	P19367	HK1	O75385	ULK1	T409	G402R	402	Missense	distal	-7	no	30.106	31.781	EPSD	ICGC;COSMIC	29.179	Up-regulation
Other_ULK_ULK_ULK1_ST	Q8TDY2	RB1CC1	O75385	ULK1	T61	T66K	66	Missense	distal	5	no	33.797	33.792	EPSD	ICGC	29.179	Down-regulation
Other_ULK_ULK_ULK1_ST	Q8TDY2	RB1CC1	O75385	ULK1	T61	R58I	58	Missense	distal	-3	no	33.797	33.645	EPSD	ICGC;COSMIC	29.179	Down-regulation
Other_ULK_ULK_ULK1_ST	Q8TDY2	RB1CC1	O75385	ULK1	S222	D221N	221	Missense	proximal	-1	no	40.072	40.363	EPSD	ICGC;COSMIC	29.179	Up-regulation
Other_ULK_ULK_ULK1_ST	Q8TDY2	RB1CC1	O75385	ULK1	S222	H226N	226	Missense	distal	4	no	40.072	38.911	EPSD	ICGC	29.179	Down-regulation
Other_ULK_ULK_ULK1_ST	Q8TDY2	RB1CC1	O75385	ULK1	S237	L240M	240	Missense	distal	3	no	35.274	31.989	EPSD	ICGC;COSMIC	29.179	Down-regulation
Other_ULK_ULK_ULK1_ST	Q8TDY2	RB1CC1	O75385	ULK1	S237	M234T	234	Missense	distal	-3	no	35.274	14.126	EPSD	ICGC;COSMIC	29.179	Loss
Other_ULK_ULK_ULK1_ST	Q8TDY2	RB1CC1	O75385	ULK1	S237	P244L	244	Missense	distal	7	no	35.274	35.258	EPSD	ICGC	29.179	Down-regulation
Other_ULK_ULK_ULK1_ST	Q8TDY2	RB1CC1	O75385	ULK1	S243	L240M	240	Missense	distal	-3	no	21.769	30.944	EPSD	ICGC;COSMIC	29.179	Gain
Other_ULK_ULK_ULK1_ST	Q8TDY2	RB1CC1	O75385	ULK1	T249	T250N	250	Missense	proximal	1	no	40.427	40.416	EPSD	ICGC;COSMIC	29.179	Down-regulation
Other_ULK_ULK_ULK1_ST	Q8TDY2	RB1CC1	O75385	ULK1	T249	P244L	244	Missense	distal	-5	no	40.427	42.278	EPSD	ICGC	29.179	Up-regulation
Other_ULK_ULK_ULK1_ST	Q8TDY2	RB1CC1	O75385	ULK1	T249	M246T	246	Missense	distal	-3	no	40.427	19.279	EPSD	ICGC;COSMIC	29.179	Loss
Other_ULK_ULK_ULK1_ST	Q8TDY2	RB1CC1	O75385	ULK1	S537	K532Q	532	Missense	distal	-5	no	28.212	30.792	EPSD	ICGC	29.179	Gain
Other_ULK_ULK_ULK1_ST	Q8TDY2	RB1CC1	O75385	ULK1	S537	A530E	530	Missense	distal	-7	no	28.212	29.909	EPSD	ICGC;COSMIC	29.179	Gain
Other_ULK_ULK_ULK1_ST	Q8TDY2	RB1CC1	O75385	ULK1	S629	T633A	633	Missense	distal	4	no	29.418	28.925	EPSD	ICGC;COSMIC	29.179	Loss
Other_ULK_ULK_ULK1_ST	Q8TDY2	RB1CC1	O75385	ULK1	S629	D626N	626	Missense	distal	-3	no	29.418	24.742	EPSD	ICGC;COSMIC	29.179	Loss
Other_ULK_ULK_ULK1_ST	Q8TDY2	RB1CC1	O75385	ULK1	T631	T633A	633	Missense	proximal	2	no	40.590	40.154	EPSD	ICGC;COSMIC	29.179	Down-regulation
Other_ULK_ULK_ULK1_ST	Q8TDY2	RB1CC1	O75385	ULK1	T631	D626N	626	Missense	distal	-5	no	40.590	39.654	EPSD	ICGC;COSMIC	29.179	Down-regulation
Other_ULK_ULK_ULK1_ST	Q8TDY2	RB1CC1	O75385	ULK1	S644	P648L	648	Missense	distal	4	no	29.276	29.154	EPSD	ICGC	29.179	Loss
Other_ULK_ULK_ULK1_ST	Q8TDY2	RB1CC1	O75385	ULK1	S836	E843Q	843	Missense	distal	7	no	40.033	40.321	EPSD	ICGC;COSMIC	29.179	Up-regulation
Other_ULK_ULK_ULK1_ST	Q8TDY2	RB1CC1	O75385	ULK1	S836	C831S	831	Missense	distal	-5	no	40.033	44.349	EPSD	ICGC;COSMIC	29.179	Up-regulation
Other_ULK_ULK_ULK1_ST	Q8TDY2	RB1CC1	O75385	ULK1	S1222	S1221R	1221	Missense	proximal	-1	no	29.966	29.438	EPSD	ICGC	29.179	Down-regulation
Other_ULK_ULK_ULK1_ST	Q8TDY2	RB1CC1	O75385	ULK1	S1222	Q1229K	1229	Missense	distal	7	no	29.966	30.054	EPSD	ICGC	29.179	Up-regulation
Other_ULK_ULK_ULK1_ST	Q8TDY2	RB1CC1	O75385	ULK1	S1284	G1282R	1282	Missense	proximal	-2	no	31.374	26.939	EPSD	ICGC;COSMIC	29.179	Loss
Other_ULK_ULK_ULK1_ST	Q8TDY2	RB1CC1	O75385	ULK1	S1284	L1291H	1291	Missense	distal	7	no	31.374	31.054	EPSD	ICGC;COSMIC	29.179	Down-regulation
Other_ULK_ULK_ULK1_ST	Q8TDY2	RB1CC1	O75385	ULK1	S1285	G1282R	1282	Missense	distal	-3	no	25.096	33.994	EPSD	ICGC;COSMIC	29.179	Gain
Other_ULK_ULK_ULK1_ST	Q8TDY2	RB1CC1	O75385	ULK1	S1286	G1282R	1282	Missense	distal	-4	no	42.267	43.086	EPSD	ICGC;COSMIC	29.179	Up-regulation
Other_ULK_ULK_ULK1_ST	Q8TDY2	RB1CC1	O75385	ULK1	S1286	L1291H	1291	Missense	distal	5	no	42.267	41.447	EPSD	ICGC;COSMIC	29.179	Down-regulation
Other_ULK_ULK_ULK1_ST	Q8TDY2	RB1CC1	O75385	ULK1	S1323	A1326E	1326	Missense	distal	3	no	32.559	31.270	PhosphoSitePlus;EPSD	ICGC	29.179	Down-regulation
Other_ULK_ULK_ULK1_ST	Q8TDY2	RB1CC1	O75385	ULK1	S1323	R1321L	1321	Missense	proximal	-2	no	32.559	30.299	PhosphoSitePlus;EPSD	ICGC	29.179	Down-regulation
Other_ULK_ULK_ULK1_ST	Q8TDY2	RB1CC1	O75385	ULK1	S1323	I1325V	1325	Missense	proximal	2	no	32.559	31.839	PhosphoSitePlus;EPSD	ICGC;COSMIC	29.179	Down-regulation
Other_ULK_ULK_ULK1_ST	Q8TDY2	RB1CC1	O75385	ULK1	S1323	A1326P	1326	Missense	distal	3	no	32.559	31.916	PhosphoSitePlus;EPSD	ICGC;COSMIC	29.179	Down-regulation
Other_ULK_ULK_ULK1_ST	Q8TDY2	RB1CC1	O75385	ULK1	S1370	A1376D	1376	Missense	distal	6	no	29.155	29.387	EPSD	ICGC	29.179	Gain
Other_ULK_ULK_ULK1_ST	Q8TDY2	RB1CC1	O75385	ULK1	S1484	R1491K	1491	Missense	distal	7	no	48.604	48.790	EPSD	ICGC;COSMIC	29.179	Up-regulation
Other_ULK_ULK_ULK1_ST	O15027	SEC16A	O75385	ULK1	S112	L114P	114	Missense	proximal	2	no	33.155	32.657	EPSD	ICGC;COSMIC	29.179	Down-regulation
Other_ULK_ULK_ULK1_ST	O15027	SEC16A	O75385	ULK1	S346	S342R	342	Missense	distal	-4	no	32.548	33.289	EPSD	ICGC;COSMIC	29.179	Up-regulation
Other_ULK_ULK_ULK1_ST	O15027	SEC16A	O75385	ULK1	S838	H835N	835	Missense	distal	-3	no	33.448	22.176	EPSD	ICGC;COSMIC	29.179	Loss
Other_ULK_ULK_ULK1_ST	O00560	SDCBP	O75385	ULK1	S6	S2F	2	Missense	distal	-4	no	29.653	24.693	EPSD;PhosphoSitePlus	ICGC	29.179	Loss
Other_ULK_ULK_ULK1_ST	O00560	SDCBP	O75385	ULK1	S6	K11N	11	Missense	distal	5	no	29.653	29.790	EPSD;PhosphoSitePlus	ICGC;COSMIC	29.179	Up-regulation
Other_ULK_ULK_ULK1_ST	O00560	SDCBP	O75385	ULK1	S6	S2Y	2	Missense	distal	-4	no	29.653	24.369	EPSD;PhosphoSitePlus	ICGC	29.179	Loss
Other_ULK_ULK_ULK1_ST	O00560	SDCBP	O75385	ULK1	S131	R128M	128	Missense	distal	-3	no	27.414	38.958	EPSD	ICGC	29.179	Gain
Other_ULK_ULK_ULK1_ST	O00560	SDCBP	O75385	ULK1	S285	M282I	282	Missense	distal	-3	no	42.351	30.654	EPSD	ICGC;COSMIC	29.179	Down-regulation
Other_ULK_ULK_ULK1_ST	O00560	SDCBP	O75385	ULK1	S285	A283T	283	Missense	proximal	-2	no	42.351	42.757	EPSD	ICGC	29.179	Up-regulation
Other_ULK_ULK_ULK1_ST	O00560	SDCBP	O75385	ULK1	S289	M282I	282	Missense	distal	-7	no	50.554	49.420	EPSD	ICGC;COSMIC	29.179	Down-regulation
Other_ULK_ULK_ULK1_ST	O00560	SDCBP	O75385	ULK1	S289	A283T	283	Missense	distal	-6	no	50.554	51.320	EPSD	ICGC	29.179	Up-regulation
Other_ULK_ULK_ULK1_ST	O00560	SDCBP	O75385	ULK1	T294	E297D	297	Missense	distal	3	no	42.852	43.680	EPSD	ICGC;COSMIC	29.179	Up-regulation
Other_ULK_ULK_ULK1_ST	Q9Y4P1	ATG4B	O75385	ULK1	S44	L50F	50	Missense	distal	6	no	41.346	40.873	EPSD	ICGC;COSMIC	29.179	Down-regulation
Other_ULK_ULK_ULK1_ST	Q8NEB9	PIK3C3	O75385	ULK1	S454	L450F	450	Missense	distal	-4	no	34.537	30.880	EPSD	ICGC	29.179	Down-regulation
Other_ULK_ULK_ULK1_ST	Q8NEB9	PIK3C3	O75385	ULK1	S454	P457H	457	Missense	distal	3	no	34.537	31.647	EPSD	ICGC;COSMIC	29.179	Down-regulation
Other_ULK_ULK_ULK1_ST	Q8NEB9	PIK3C3	O75385	ULK1	S454	P457T	457	Missense	distal	3	no	34.537	32.100	EPSD	ICGC;COSMIC	29.179	Down-regulation
Other_ULK_ULK_ULK1_ST	Q8NEB9	PIK3C3	O75385	ULK1	S460	E464Q	464	Missense	distal	4	no	31.859	31.595	EPSD	ICGC;COSMIC	29.179	Down-regulation
Other_ULK_ULK_ULK1_ST	Q8NEB9	PIK3C3	O75385	ULK1	S460	P457H	457	Missense	distal	-3	no	31.859	39.570	EPSD	ICGC;COSMIC	29.179	Up-regulation
Other_ULK_ULK_ULK1_ST	Q8NEB9	PIK3C3	O75385	ULK1	S460	V465F	465	Missense	distal	5	no	31.859	32.334	EPSD	ICGC	29.179	Up-regulation
Other_ULK_ULK_ULK1_ST	Q8NEB9	PIK3C3	O75385	ULK1	S460	P457T	457	Missense	distal	-3	no	31.859	29.616	EPSD	ICGC;COSMIC	29.179	Down-regulation
Other_ULK_ULK_ULK1_ST	A2RUS2	DENND3	O75385	ULK1	S445	P449L	449	Missense	distal	4	no	30.698	30.575	EPSD	ICGC;COSMIC;GDSC	29.179	Down-regulation
Other_ULK_ULK_ULK1_ST	A2RUS2	DENND3	O75385	ULK1	S460	S456T	456	Missense	distal	-4	no	30.033	29.665	EPSD	ICGC;COSMIC	29.179	Down-regulation
Other_ULK_ULK_ULK1_ST	A2RUS2	DENND3	O75385	ULK1	S460	R457W	457	Missense	distal	-3	no	30.033	16.374	EPSD	ICGC;COSMIC	29.179	Loss
Other_ULK_ULK_ULK1_ST	A2RUS2	DENND3	O75385	ULK1	S460	H461Y	461	Missense	proximal	1	no	30.033	29.964	EPSD	ICGC;COSMIC	29.179	Down-regulation
Other_ULK_ULK_ULK1_ST	A2RUS2	DENND3	O75385	ULK1	T494	R500T	500	Missense	distal	6	no	32.472	32.696	EPSD	ICGC;COSMIC	29.179	Up-regulation
Other_ULK_ULK_ULK1_ST	A2RUS2	DENND3	O75385	ULK1	S632	H637Y	637	Missense	distal	5	no	27.851	29.865	EPSD	ICGC	29.179	Gain
Other_ULK_ULK_ULK1_ST	Q9C0C7	AMBRA1	O75385	ULK1	S635	S639T	639	Missense	distal	4	no	46.392	46.028	PhosphoSitePlus;EPSD	ICGC;COSMIC	29.179	Down-regulation
Other_ULK_ULK_ULK1_ST	Q9C0C7	AMBRA1	O75385	ULK1	S637	S639T	639	Missense	proximal	2	no	30.996	30.519	EPSD	ICGC;COSMIC	29.179	Down-regulation
Other_ULK_ULK_ULK1_ST	Q9C0C7	AMBRA1	O75385	ULK1	S1072	T1075M	1075	Missense	distal	3	no	29.853	28.564	EPSD	ICGC;COSMIC	29.179	Loss
Other_ULK_ULK_ULK1_ST	Q9C0C7	AMBRA1	O75385	ULK1	S1072	R1068H	1068	Missense	distal	-4	no	29.853	30.979	EPSD	ICGC;COSMIC	29.179	Up-regulation
Other_ULK_ULK_ULK1_ST	Q9C0C7	AMBRA1	O75385	ULK1	S1072	T1075K	1075	Missense	distal	3	no	29.853	34.405	EPSD	ICGC	29.179	Up-regulation
Other_ULK_ULK_ULK1_ST	Q9C0C7	AMBRA1	O75385	ULK1	S1072	S1066N	1066	Missense	distal	-6	no	29.853	28.579	EPSD	ICGC;COSMIC	29.179	Loss
Other_ULK_ULK_ULK1_ST	Q13045	FLII	O75385	ULK1	S436	R431K	431	Missense	distal	-5	no	34.426	33.976	EPSD	ICGC;COSMIC	29.179	Down-regulation
Other_ULK_ULK_ULK1_ST	Q13045	FLII	O75385	ULK1	S436	D439G	439	Missense	distal	3	no	34.426	31.940	EPSD	ICGC	29.179	Down-regulation
Other_ULK_ULK_ULK1_ST	Q13045	FLII	O75385	ULK1	S822	A817V	817	Missense	distal	-5	no	39.142	39.670	EPSD	ICGC;COSMIC	29.179	Up-regulation
Other_ULK_ULK_ULK1_ST	Q13045	FLII	O75385	ULK1	S822	V819A	819	Missense	distal	-3	no	39.142	31.507	EPSD	ICGC	29.179	Down-regulation
Other_ULK_ULK_ULK1_ST	Q13045	FLII	O75385	ULK1	T826	V819A	819	Missense	distal	-7	no	28.636	29.604	EPSD	ICGC	29.179	Gain
CMGC_MAPK_JNK_MAPK9_ST	O95140	MFN2	P45984-2	MAPK9	S27	T34A	34	Missense	distal	7	no	162.281	161.682	PhosphoSitePlus	ICGC;COSMIC	140.458	Down-regulation
CMGC_MAPK_JNK_MAPK9_ST	P40763	STAT3	P45984-2	MAPK9	T118	R114S	114	Missense	distal	-4	no	142.719	143.017	EPSD	ICGC	140.458	Up-regulation
CMGC_MAPK_JNK_MAPK9_ST	P40763	STAT3	P45984-2	MAPK9	T118	L115I	115	Missense	distal	-3	no	142.719	141.864	EPSD	ICGC;COSMIC	140.458	Down-regulation
CMGC_MAPK_JNK_MAPK9_ST	P40763	STAT3	P45984-2	MAPK9	S319	L312M	312	Missense	distal	-7	no	138.218	140.732	EPSD	ICGC	140.458	Gain
CMGC_MAPK_JNK_MAPK9_ST	P40763	STAT3	P45984-2	MAPK9	S701	A702T	702	Missense	proximal	1	no	144.745	144.193	EPSD	ICGC;COSMIC	140.458	Down-regulation
CMGC_MAPK_JNK_MAPK9_ST	P40763	STAT3	P45984-2	MAPK9	T714	T717N	717	Missense	distal	3	no	149.040	149.282	EPSD	ICGC	140.458	Up-regulation
CMGC_MAPK_JNK_MAPK9_ST	P40763	STAT3	P45984-2	MAPK9	T714	P715L	715	Missense	proximal	1	no	149.040	104.138	EPSD	ICGC	140.458	Loss
CMGC_MAPK_JNK_MAPK9_ST	P40763	STAT3	P45984-2	MAPK9	T714	P715Q	715	Missense	proximal	1	no	149.040	128.928	EPSD	ICGC;COSMIC	140.458	Loss
CMGC_MAPK_JNK_MAPK9_ST	P40763	STAT3	P45984-2	MAPK9	S727	L724P	724	Missense	distal	-3	no	156.513	158.086	PhosphoSitePlus	ICGC;COSMIC	140.458	Up-regulation
CMGC_MAPK_JNK_MAPK9_ST	P40763	STAT3	P45984-2	MAPK9	S727	S727P	727	Missense	central	0	yes	156.513	0.000	PhosphoSitePlus	ICGC	140.458	Loss
CMGC_MAPK_JNK_MAPK9_ST	P40763	STAT3	P45984-2	MAPK9	S727	L734S	734	Missense	distal	7	no	156.513	156.102	PhosphoSitePlus	ICGC;COSMIC	140.458	Down-regulation
TK_Tec_TEC_Y	Q06187	BTK	P42680	TEC	Y223	M228I	228	Missense	distal	5	no	353.276	344.013	PhosphoSitePlus	ICGC;COSMIC	232.776	Down-regulation
TK_Tec_TEC_Y	Q06187	BTK	P42680	TEC	Y223	A221D	221	Missense	proximal	-2	no	353.276	299.459	PhosphoSitePlus	ICGC	232.776	Down-regulation
TK_Tec_TEC_Y	Q06187	BTK	P42680	TEC	Y223	M228T	228	Missense	distal	5	no	353.276	352.002	PhosphoSitePlus	ICGC;COSMIC	232.776	Down-regulation
TK_Tec_TEC_Y	Q06187	BTK	P42680	TEC	Y315	V317G	317	Missense	proximal	2	no	255.030	261.050	EPSD	ICGC;COSMIC	232.776	Up-regulation
TK_Tec_TEC_Y	Q06187	BTK	P42680	TEC	Y315	A312T	312	Missense	distal	-3	no	255.030	186.654	EPSD	ICGC	232.776	Loss
TK_Tec_TEC_Y	Q06187	BTK	P42680	TEC	Y315	D308V	308	Missense	distal	-7	no	255.030	249.985	EPSD	ICGC	232.776	Down-regulation
TK_Tec_TEC_Y	Q06187	BTK	P42680	TEC	Y551	K558T	558	Missense	distal	7	no	364.283	363.732	EPSD	ICGC	232.776	Down-regulation
TK_Tec_TEC_Y	Q08881	ITK	P42680	TEC	Y146	K150E	150	Missense	distal	4	no	284.658	287.936	EPSD	ICGC;COSMIC	232.776	Up-regulation
TK_Tec_TEC_Y	Q08881	ITK	P42680	TEC	Y146	T149I	149	Missense	distal	3	no	284.658	280.846	EPSD	ICGC;COSMIC	232.776	Down-regulation
TK_Tec_TEC_Y	Q08881	ITK	P42680	TEC	Y146	A152S	152	Missense	distal	6	no	284.658	279.466	EPSD	ICGC	232.776	Down-regulation
TK_Tec_TEC_Y	Q08881	ITK	P42680	TEC	Y146	T149N	149	Missense	distal	3	no	284.658	289.238	EPSD	ICGC	232.776	Up-regulation
TK_Tec_TEC_Y	Q08881	ITK	P42680	TEC	Y512	D510A	510	Missense	proximal	-2	no	406.594	460.411	EPSD	ICGC	232.776	Up-regulation
TK_Tec_TEC_Y	Q99952	PTPN18	P42680	TEC	Y281	R282S	282	Missense	proximal	1	no	286.893	284.409	PhosphoSitePlus;EPSD	ICGC	232.776	Down-regulation
TK_Tec_TEC_Y	Q99952	PTPN18	P42680	TEC	Y281	R282M	282	Missense	proximal	1	no	286.893	285.947	PhosphoSitePlus;EPSD	ICGC	232.776	Down-regulation
TK_Tec_TEC_Y	Q99952	PTPN18	P42680	TEC	Y281	Q280E	280	Missense	proximal	-1	no	286.893	287.016	PhosphoSitePlus;EPSD	ICGC;COSMIC	232.776	Up-regulation
TK_Tec_TEC_Y	Q99952	PTPN18	P42680	TEC	Y314	D316N	316	Missense	proximal	2	no	260.056	255.968	EPSD	ICGC;COSMIC	232.776	Down-regulation
TK_Tec_TEC_Y	Q99952	PTPN18	P42680	TEC	Y314	R321W	321	Missense	distal	7	no	260.056	260.879	EPSD	ICGC;COSMIC	232.776	Up-regulation
TK_Tec_TEC_Y	Q99952	PTPN18	P42680	TEC	Y354	Q358L	358	Missense	distal	4	no	448.162	429.844	EPSD;PhosphoSitePlus	ICGC	232.776	Down-regulation
TK_Tec_TEC_Y	Q99952	PTPN18	P42680	TEC	Y354	G361V	361	Missense	distal	7	no	448.162	448.760	EPSD;PhosphoSitePlus	ICGC	232.776	Up-regulation
TK_Tec_TEC_Y	Q99952	PTPN18	P42680	TEC	Y389	S390R	390	Missense	proximal	1	no	368.923	371.407	EPSD;PhosphoSitePlus	ICGC;COSMIC	232.776	Up-regulation
TK_Tec_TEC_Y	P09038	FGF2	P42680	TEC	Y215	A212S	212	Missense	distal	-3	no	433.447	418.660	EPSD	ICGC	232.776	Down-regulation
TK_Tec_TEC_Y	P09038	FGF2	P42680	TEC	Y215	R214H	214	Missense	proximal	-1	no	433.447	435.018	EPSD	ICGC	232.776	Up-regulation
TK_Tec_TEC_Y	P09038	FGF2	P42680	TEC	Y257	S255I	255	Missense	proximal	-2	no	352.187	251.204	EPSD	ICGC	232.776	Down-regulation
TK_Tec_TEC_Y	P09038	FGF2	P42680	TEC	Y257	G264W	264	Missense	distal	7	no	352.187	352.436	EPSD	ICGC;COSMIC	232.776	Up-regulation
TK_Tec_TEC_Y	P51813	BMX	P42680	TEC	Y202	K199T	199	Missense	distal	-3	no	353.268	349.830	EPSD	ICGC;COSMIC	232.776	Down-regulation
TK_Tec_TEC_Y	P51813	BMX	P42680	TEC	Y216	K221N	221	Missense	distal	5	no	389.832	393.856	PhosphoSitePlus	ICGC;COSMIC	232.776	Up-regulation
TK_Tec_TEC_Y	P51813	BMX	P42680	TEC	Y216	S212R	212	Missense	distal	-4	no	389.832	381.987	PhosphoSitePlus	ICGC;COSMIC	232.776	Down-regulation
TK_Tec_TEC_Y	P51813	BMX	P42680	TEC	Y224	K221N	221	Missense	distal	-3	no	336.946	351.619	EPSD	ICGC;COSMIC	232.776	Up-regulation
TK_Tec_TEC_Y	P51813	BMX	P42680	TEC	Y224	G225S	225	Missense	proximal	1	no	336.946	333.648	EPSD	ICGC;COSMIC	232.776	Down-regulation
TK_Tec_TEC_Y	P51813	BMX	P42680	TEC	Y224	G225D	225	Missense	proximal	1	no	336.946	335.143	EPSD	ICGC;COSMIC	232.776	Down-regulation
TK_Tec_TEC_Y	P51813	BMX	P42680	TEC	Y365	S369F	369	Missense	distal	4	no	245.470	209.780	EPSD	ICGC;COSMIC	232.776	Loss
TK_Tec_TEC_Y	P51813	BMX	P42680	TEC	Y365	F367Y	367	Missense	proximal	2	no	245.470	249.019	EPSD	ICGC;COSMIC	232.776	Up-regulation
TK_Tec_TEC_Y	P51813	BMX	P42680	TEC	Y566	G571R	571	Missense	distal	5	no	380.532	379.341	EPSD	ICGC;COSMIC	232.776	Down-regulation
TK_Tec_TEC_Y	P42680	TEC	P42680	TEC	Y188	M187V	187	Missense	proximal	-1	no	330.850	331.689	EPSD	ICGC;COSMIC	232.776	Up-regulation
TK_Tec_TEC_Y	P42680	TEC	P42680	TEC	Y188	V185A	185	Missense	distal	-3	no	330.850	413.141	EPSD	ICGC	232.776	Up-regulation
TK_Tec_TEC_Y	P42680	TEC	P42680	TEC	Y188	G195R	195	Missense	distal	7	no	330.850	330.276	EPSD	ICGC;COSMIC	232.776	Down-regulation
TK_Tec_TEC_Y	P42680	TEC	P42680	TEC	Y513	Q518K	518	Missense	distal	5	no	302.507	300.486	EPSD	ICGC;COSMIC	232.776	Down-regulation
TK_Tec_TEC_Y	P42680	TEC	P42680	TEC	Y519	Q518K	518	Missense	proximal	-1	no	424.813	425.463	EPSD	ICGC;COSMIC	232.776	Up-regulation
Other_TLK_TLK1_ST	Q99638	RAD9A	Q9UKI8	TLK1	S270	Q273E	273	Missense	distal	3	no	2.666	2.687	EPSD	ICGC;COSMIC	2.233	Up-regulation
Other_TLK_TLK1_ST	Q99638	RAD9A	Q9UKI8	TLK1	S270	L265I	265	Missense	distal	-5	no	2.666	2.593	EPSD	ICGC	2.233	Down-regulation
Other_TLK_TLK1_ST	Q99638	RAD9A	Q9UKI8	TLK1	S272	L265I	265	Missense	distal	-7	no	2.168	2.327	EPSD	ICGC	2.233	Gain
Other_TLK_TLK1_ST	Q99638	RAD9A	Q9UKI8	TLK1	S324	R320L	320	Missense	distal	-4	no	2.058	2.249	EPSD	ICGC;COSMIC	2.233	Gain
Other_TLK_TLK1_ST	Q99638	RAD9A	Q9UKI8	TLK1	S328	P331S	331	Missense	distal	3	no	6.148	6.143	PhosphoSitePlus;EPSD	ICGC	2.233	Down-regulation
Other_TLK_TLK1_ST	Q99638	RAD9A	Q9UKI8	TLK1	T355	P349S	349	Missense	distal	-6	no	6.265	6.218	EPSD;PhosphoSitePlus	ICGC;COSMIC	2.233	Down-regulation
Other_TLK_TLK1_ST	Q96PY6	NEK1	Q9UKI8	TLK1	S14	A18V	18	Missense	distal	4	no	6.636	6.351	EPSD;PhosphoSitePlus	ICGC;COSMIC	2.233	Down-regulation
Other_TLK_TLK1_ST	Q96PY6	NEK1	Q9UKI8	TLK1	T141	L144F	144	Missense	distal	3	no	6.257	6.260	EPSD;PhosphoSitePlus	ICGC	2.233	Up-regulation
Other_TLK_TLK1_ST	Q96PY6	NEK1	Q9UKI8	TLK1	S439	P434L	434	Missense	distal	-5	no	2.260	2.243	EPSD	ICGC;COSMIC	2.233	Down-regulation
Other_TLK_TLK1_ST	Q96PY6	NEK1	Q9UKI8	TLK1	T1104	D1103G	1103	Missense	proximal	-1	no	2.628	2.982	EPSD	ICGC;COSMIC	2.233	Up-regulation
Other_TLK_TLK1_ST	Q96PY6	NEK1	Q9UKI8	TLK1	T1104	D1103N	1103	Missense	proximal	-1	no	2.628	2.795	EPSD	ICGC;COSMIC	2.233	Up-regulation
CMGC_CDK_CDC2_CDK1_ST	O15151	MDM4	P06493	CDK1	S20	S20F	20	Missense	central	0	yes	3.656	0.000	EPSD	ICGC;COSMIC	3.158	Loss
CMGC_CDK_CDC2_CDK1_ST	P11388	TOP2A	P06493	CDK1	S4	P8S	8	Missense	distal	4	no	3.479	3.475	EPSD	ICGC;COSMIC	3.158	Down-regulation
CMGC_CDK_CDC2_CDK1_ST	P11388	TOP2A	P06493	CDK1	S802	A801D	801	Missense	proximal	-1	no	3.372	3.510	EPSD	ICGC	3.158	Up-regulation
CMGC_CDK_CDC2_CDK1_ST	Q99638	RAD9A	P06493	CDK1	T292	D297Y	297	Missense	distal	5	no	3.534	3.564	EPSD;PhosphoSitePlus	ICGC	3.158	Up-regulation
CMGC_CDK_CDC2_CDK1_ST	Q99638	RAD9A	P06493	CDK1	S375	R374H	374	Missense	proximal	-1	no	3.385	3.409	EPSD	ICGC	3.158	Up-regulation
CMGC_CDK_CDC2_CDK1_ST	Q99638	RAD9A	P06493	CDK1	S375	P372H	372	Missense	distal	-3	no	3.385	3.369	EPSD	ICGC	3.158	Down-regulation
CMGC_CDK_CDC2_CDK1_ST	Q99638	RAD9A	P06493	CDK1	S375	Q377K	377	Missense	proximal	2	no	3.385	3.388	EPSD	ICGC;COSMIC	3.158	Up-regulation
CMGC_CDK_CDC2_CDK1_ST	Q99638	RAD9A	P06493	CDK1	S380	R374H	374	Missense	distal	-6	no	3.427	3.432	EPSD	ICGC	3.158	Up-regulation
CMGC_CDK_CDC2_CDK1_ST	Q99638	RAD9A	P06493	CDK1	S380	Q377K	377	Missense	distal	-3	no	3.427	3.394	EPSD	ICGC;COSMIC	3.158	Down-regulation
CMGC_CDK_CDC2_CDK1_ST	P49792	RANBP2	P06493	CDK1	T19	S26L	26	Missense	distal	7	no	3.188	3.218	EPSD	ICGC;COSMIC	3.158	Up-regulation
CMGC_CDK_CDC2_CDK1_ST	P49792	RANBP2	P06493	CDK1	T19	P20Q	20	Missense	proximal	1	no	3.188	0.765	EPSD	ICGC;COSMIC	3.158	Loss
CMGC_CDK_CDC2_CDK1_ST	P49792	RANBP2	P06493	CDK1	S394	S391C	391	Missense	distal	-3	no	3.287	3.271	EPSD	ICGC;COSMIC	3.158	Down-regulation
CMGC_CDK_CDC2_CDK1_ST	P49792	RANBP2	P06493	CDK1	S700	E695A	695	Missense	distal	-5	no	3.234	3.157	EPSD	ICGC;COSMIC	3.158	Loss
CMGC_CDK_CDC2_CDK1_ST	P49792	RANBP2	P06493	CDK1	T799	R802Q	802	Missense	distal	3	no	3.203	3.155	EPSD	ICGC;COSMIC;GDSC	3.158	Loss
CMGC_CDK_CDC2_CDK1_ST	P49792	RANBP2	P06493	CDK1	T799	P797S	797	Missense	proximal	-2	no	3.203	3.330	EPSD	ICGC;COSMIC	3.158	Up-regulation
CMGC_CDK_CDC2_CDK1_ST	P49792	RANBP2	P06493	CDK1	S1249	C1243Y	1243	Missense	distal	-6	no	3.568	3.569	EPSD	ICGC;COSMIC	3.158	Up-regulation
CMGC_CDK_CDC2_CDK1_ST	P49792	RANBP2	P06493	CDK1	S1249	N1245S	1245	Missense	distal	-4	no	3.568	3.641	EPSD	ICGC	3.158	Up-regulation
CMGC_CDK_CDC2_CDK1_ST	P49792	RANBP2	P06493	CDK1	S1249	P1250A	1250	Missense	proximal	1	no	3.568	2.679	EPSD	ICGC;COSMIC	3.158	Loss
CMGC_CDK_CDC2_CDK1_ST	P49792	RANBP2	P06493	CDK1	S1249	H1246Y	1246	Missense	distal	-3	no	3.568	3.552	EPSD	ICGC	3.158	Down-regulation
CMGC_CDK_CDC2_CDK1_ST	P49792	RANBP2	P06493	CDK1	T1255	P1250A	1250	Missense	distal	-5	no	3.395	3.349	EPSD	ICGC;COSMIC	3.158	Down-regulation
CMGC_CDK_CDC2_CDK1_ST	P49792	RANBP2	P06493	CDK1	T1412	R1407Q	1407	Missense	distal	-5	no	3.716	3.684	EPSD	ICGC;COSMIC	3.158	Down-regulation
CMGC_CDK_CDC2_CDK1_ST	P49792	RANBP2	P06493	CDK1	S1573	S1573I	1573	Missense	central	0	yes	3.199	0.000	EPSD	ICGC	3.158	Loss
CMGC_CDK_CDC2_CDK1_ST	P49792	RANBP2	P06493	CDK1	T1761	A1763V	1763	Missense	proximal	2	no	3.468	3.490	EPSD	ICGC;COSMIC	3.158	Up-regulation
CMGC_CDK_CDC2_CDK1_ST	P49792	RANBP2	P06493	CDK1	S1869	V1864M	1864	Missense	distal	-5	no	3.179	3.118	EPSD	ICGC;COSMIC	3.158	Loss
CMGC_CDK_CDC2_CDK1_ST	P49792	RANBP2	P06493	CDK1	S1869	S1871L	1871	Missense	proximal	2	no	3.179	3.201	EPSD	ICGC	3.158	Up-regulation
CMGC_CDK_CDC2_CDK1_ST	P49792	RANBP2	P06493	CDK1	S1869	Q1875H	1875	Missense	distal	6	no	3.179	3.177	EPSD	ICGC	3.158	Down-regulation
CMGC_CDK_CDC2_CDK1_ST	P49792	RANBP2	P06493	CDK1	T2128	Q2121R	2121	Missense	distal	-7	no	3.509	3.503	EPSD	ICGC;COSMIC	3.158	Down-regulation
CMGC_CDK_CDC2_CDK1_ST	P49792	RANBP2	P06493	CDK1	T2450	S2447F	2447	Missense	distal	-3	no	3.386	3.359	EPSD	ICGC;COSMIC	3.158	Down-regulation
CMGC_CDK_CDC2_CDK1_ST	P49792	RANBP2	P06493	CDK1	T2504	P2505T	2505	Missense	proximal	1	no	3.196	0.763	EPSD	ICGC;COSMIC	3.158	Loss
CMGC_CDK_CDC2_CDK1_ST	P30291	WEE1	P06493	CDK1	S127	A130V	130	Missense	distal	3	no	3.203	3.050	EPSD	ICGC;COSMIC	3.158	Loss
CMGC_CDK_CDC2_CDK1_ST	P30291	WEE1	P06493	CDK1	T187	L182V	182	Missense	distal	-5	no	3.376	3.349	EPSD	ICGC;COSMIC	3.158	Down-regulation
CMGC_CDK_CDC2_CDK1_ST	P30291	WEE1	P06493	CDK1	S472	H466Y	466	Missense	distal	-6	no	3.226	3.232	EPSD	ICGC	3.158	Up-regulation
CMGC_CDK_CDC2_CDK1_ST	Q07820	MCL1	P06493	CDK1	S121	I119V	119	Missense	proximal	-2	no	3.429	3.380	EPSD	ICGC;COSMIC	3.158	Down-regulation
CMGC_CDK_CDC2_CDK1_ST	Q07820	MCL1	P06493	CDK1	S121	E125D	125	Missense	distal	4	no	3.429	3.428	EPSD	ICGC;COSMIC	3.158	Down-regulation
CMGC_CDK_CDC2_CDK1_ST	Q07820	MCL1	P06493	CDK1	T163	P161S	161	Missense	proximal	-2	no	3.054	3.180	EPSD	ICGC;COSMIC	3.158	Gain
CMGC_CDK_CDC2_CDK1_ST	Q14980	NUMA1	P06493	CDK1	S112	T107A	107	Missense	distal	-5	no	3.226	3.205	EPSD	ICGC;COSMIC	3.158	Down-regulation
CMGC_CDK_CDC2_CDK1_ST	Q14980	NUMA1	P06493	CDK1	S203	S200Y	200	Missense	distal	-3	no	3.170	3.138	EPSD	ICGC	3.158	Loss
CMGC_CDK_CDC2_CDK1_ST	Q14980	NUMA1	P06493	CDK1	S203	Q210K	210	Missense	distal	7	no	3.170	3.176	EPSD	ICGC;COSMIC	3.158	Up-regulation
CMGC_CDK_CDC2_CDK1_ST	Q14980	NUMA1	P06493	CDK1	S203	G199S	199	Missense	distal	-4	no	3.170	3.308	EPSD	ICGC	3.158	Up-regulation
CMGC_CDK_CDC2_CDK1_ST	Q96FF9	CDCA5	P06493	CDK1	S21	R18S	18	Missense	distal	-3	no	3.327	3.353	EPSD;PhosphoSitePlus	ICGC;COSMIC	3.158	Up-regulation
CMGC_CDK_CDC2_CDK1_ST	Q96FF9	CDCA5	P06493	CDK1	S21	P20T	20	Missense	proximal	-1	no	3.327	3.249	EPSD;PhosphoSitePlus	ICGC;COSMIC	3.158	Down-regulation
CMGC_CDK_CDC2_CDK1_ST	Q96FF9	CDCA5	P06493	CDK1	S79	S83F	83	Missense	distal	4	no	3.218	3.122	EPSD;PhosphoSitePlus	ICGC	3.158	Loss
CMGC_CDK_CDC2_CDK1_ST	Q99728	BARD1	P06493	CDK1	S288	P281Q	281	Missense	distal	-7	no	3.330	3.341	EPSD;PhosphoSitePlus	ICGC;COSMIC	3.158	Up-regulation
CMGC_CDK_CDC2_CDK1_ST	Q99728	BARD1	P06493	CDK1	S496	Q493E	493	Missense	distal	-3	no	3.257	3.235	EPSD	ICGC;COSMIC	3.158	Down-regulation
CMGC_CDK_CDC2_CDK1_ST	Q99728	BARD1	P06493	CDK1	S496	L498I	498	Missense	proximal	2	no	3.257	3.256	EPSD	ICGC;COSMIC	3.158	Down-regulation
CMGC_CDK_CDC2_CDK1_ST	Q9NXR1	NDE1	P06493	CDK1	S333	P334L	334	Missense	proximal	1	no	3.202	-0.485	EPSD	ICGC	3.158	Loss
CMGC_CDK_CDC2_CDK1_ST	Q9NXR1	NDE1	P06493	CDK1	S333	Q339H	339	Missense	distal	6	no	3.202	3.200	EPSD	ICGC	3.158	Down-regulation
CMGC_CDK_CDC2_CDK1_ST	Q9NXR1	NDE1	P06493	CDK1	S333	S337L	337	Missense	distal	4	no	3.202	3.083	EPSD	ICGC	3.158	Loss
CMGC_CDK_CDC2_CDK1_ST	Q9NXR1	NDE1	P06493	CDK1	S333	S333L	333	Missense	central	0	yes	3.202	0.000	EPSD	ICGC	3.158	Loss
CMGC_CDK_CDC2_CDK1_ST	Q9NXR1	NDE1	P06493	CDK1	S333	S331L	331	Missense	proximal	-2	no	3.202	3.249	EPSD	ICGC	3.158	Up-regulation
CMGC_CDK_CDC2_CDK1_ST	P21333	FLNA	P06493	CDK1	S564	G571A	571	Missense	distal	7	no	3.192	3.154	EPSD	ICGC;COSMIC	3.158	Loss
CMGC_CDK_CDC2_CDK1_ST	P21333	FLNA	P06493	CDK1	S959	P955H	955	Missense	distal	-4	no	3.387	3.368	EPSD	ICGC;COSMIC	3.158	Down-regulation
CMGC_CDK_CDC2_CDK1_ST	P21333	FLNA	P06493	CDK1	S959	G953V	953	Missense	distal	-6	no	3.387	3.383	EPSD	ICGC;COSMIC	3.158	Down-regulation
CMGC_CDK_CDC2_CDK1_ST	P21333	FLNA	P06493	CDK1	S1055	P1056H	1056	Missense	proximal	1	no	3.229	0.545	EPSD	ICGC;COSMIC	3.158	Loss
CMGC_CDK_CDC2_CDK1_ST	P21333	FLNA	P06493	CDK1	S1055	V1052M	1052	Missense	distal	-3	no	3.229	3.235	EPSD	ICGC;COSMIC;GDSC;CCLE	3.158	Up-regulation
CMGC_CDK_CDC2_CDK1_ST	P21333	FLNA	P06493	CDK1	S1055	G1049S	1049	Missense	distal	-6	no	3.229	3.206	EPSD	ICGC;COSMIC	3.158	Down-regulation
CMGC_CDK_CDC2_CDK1_ST	P21333	FLNA	P06493	CDK1	S2033	S2032R	2032	Missense	proximal	-1	no	3.370	3.433	EPSD	ICGC;COSMIC	3.158	Up-regulation
CMGC_CDK_CDC2_CDK1_ST	P21333	FLNA	P06493	CDK1	S2640	P2638T	2638	Missense	proximal	-2	no	3.246	3.334	EPSD	ICGC;COSMIC	3.158	Up-regulation
CMGC_CDK_CDC2_CDK1_ST	P08047	SP1	P06493	CDK1	T739	A738G	738	Missense	proximal	-1	no	3.132	3.406	EPSD;PhosphoSitePlus	ICGC;COSMIC	3.158	Gain
CMGC_CDK_CDC2_CDK1_ST	P19338	NCL	P06493	CDK1	S67	T69K	69	Missense	proximal	2	no	3.190	3.195	EPSD	ICGC	3.158	Up-regulation
CMGC_CDK_CDC2_CDK1_ST	P19338	NCL	P06493	CDK1	S67	A61S	61	Missense	distal	-6	no	3.190	3.192	EPSD	ICGC;COSMIC	3.158	Up-regulation
CMGC_CDK_CDC2_CDK1_ST	P19338	NCL	P06493	CDK1	T99	A103E	103	Missense	distal	4	no	3.806	3.702	EPSD	ICGC	3.158	Down-regulation
CMGC_CDK_CDC2_CDK1_ST	P19338	NCL	P06493	CDK1	T99	T106K	106	Missense	distal	7	no	3.806	3.813	EPSD	ICGC	3.158	Up-regulation
CMGC_CDK_CDC2_CDK1_ST	P19338	NCL	P06493	CDK1	T99	A101D	101	Missense	proximal	2	no	3.806	3.823	EPSD	ICGC	3.158	Up-regulation
CMGC_CDK_CDC2_CDK1_ST	P19338	NCL	P06493	CDK1	T106	A112V	112	Missense	distal	6	no	3.480	3.433	EPSD	ICGC;COSMIC	3.158	Down-regulation
CMGC_CDK_CDC2_CDK1_ST	P19338	NCL	P06493	CDK1	T106	A103E	103	Missense	distal	-3	no	3.480	3.412	EPSD	ICGC	3.158	Down-regulation
CMGC_CDK_CDC2_CDK1_ST	P19338	NCL	P06493	CDK1	T106	T106K	106	Missense	central	0	yes	3.480	0.000	EPSD	ICGC	3.158	Loss
CMGC_CDK_CDC2_CDK1_ST	P19338	NCL	P06493	CDK1	T106	A101D	101	Missense	distal	-5	no	3.480	3.548	EPSD	ICGC	3.158	Up-regulation
CMGC_CDK_CDC2_CDK1_ST	P19338	NCL	P06493	CDK1	T113	A112V	112	Missense	proximal	-1	no	3.440	3.640	EPSD	ICGC;COSMIC	3.158	Up-regulation
CMGC_CDK_CDC2_CDK1_ST	P19338	NCL	P06493	CDK1	T113	T106K	106	Missense	distal	-7	no	3.440	3.308	EPSD	ICGC	3.158	Down-regulation
CMGC_CDK_CDC2_CDK1_ST	Q14135	VGLL4	P06493	CDK1	S103	R107H	107	Missense	distal	4	no	3.240	3.199	EPSD	ICGC;COSMIC	3.158	Down-regulation
CMGC_CDK_CDC2_CDK1_ST	Q14135	VGLL4	P06493	CDK1	S103	R98W	98	Missense	distal	-5	no	3.240	3.265	EPSD	ICGC;COSMIC;CCLE	3.158	Up-regulation
CMGC_CDK_CDC2_CDK1_ST	Q14135	VGLL4	P06493	CDK1	S103	A110T	110	Missense	distal	7	no	3.240	3.254	EPSD	ICGC	3.158	Up-regulation
CMGC_CDK_CDC2_CDK1_ST	Q14135	VGLL4	P06493	CDK1	S103	A110V	110	Missense	distal	7	no	3.240	3.274	EPSD	ICGC;COSMIC	3.158	Up-regulation
CMGC_CDK_CDC2_CDK1_ST	Q14135	VGLL4	P06493	CDK1	S103	S103N	103	Missense	central	0	yes	3.240	0.000	EPSD	ICGC;COSMIC	3.158	Loss
CMGC_CDK_CDC2_CDK1_ST	Q14135	VGLL4	P06493	CDK1	S149	G147S	147	Missense	proximal	-2	no	3.282	3.192	EPSD	ICGC;COSMIC	3.158	Down-regulation
CMGC_CDK_CDC2_CDK1_ST	O95139	NDUFB6	P06493	CDK1	T5	L12M	12	Missense	distal	7	no	3.205	3.186	EPSD;PhosphoSitePlus	ICGC	3.158	Down-regulation
CMGC_CDK_CDC2_CDK1_ST	O95139	NDUFB6	P06493	CDK1	T5	P6Q	6	Missense	proximal	1	no	3.205	0.782	EPSD;PhosphoSitePlus	ICGC	3.158	Loss
CMGC_CDK_CDC2_CDK1_ST	O95139	NDUFB6	P06493	CDK1	S29	K24N	24	Missense	distal	-5	no	3.676	3.640	PhosphoSitePlus;EPSD	ICGC;COSMIC	3.158	Down-regulation
CMGC_CDK_CDC2_CDK1_ST	O95139	NDUFB6	P06493	CDK1	S29	L28M	28	Missense	proximal	-1	no	3.676	3.563	PhosphoSitePlus;EPSD	ICGC	3.158	Down-regulation
CMGC_CDK_CDC2_CDK1_ST	O95139	NDUFB6	P06493	CDK1	S29	D25E	25	Missense	distal	-4	no	3.676	3.675	PhosphoSitePlus;EPSD	ICGC	3.158	Down-regulation
CMGC_CDK_CDC2_CDK1_ST	Q9HCH0	NCKAP5L	P06493	CDK1	S492	R485L	485	Missense	distal	-7	no	3.444	3.279	EPSD	ICGC;COSMIC	3.158	Down-regulation
CMGC_CDK_CDC2_CDK1_ST	Q9HCH0	NCKAP5L	P06493	CDK1	S806	P807H	807	Missense	proximal	1	no	3.247	0.563	EPSD	ICGC	3.158	Loss
CMGC_CDK_CDC2_CDK1_ST	Q9HCH0	NCKAP5L	P06493	CDK1	S806	S810G	810	Missense	distal	4	no	3.247	3.140	EPSD	ICGC;COSMIC	3.158	Loss
CMGC_CDK_CDC2_CDK1_ST	Q9HCH0	NCKAP5L	P06493	CDK1	T1289	S1291R	1291	Missense	proximal	2	no	3.769	3.776	EPSD	ICGC	3.158	Up-regulation
CMGC_CDK_CDC2_CDK1_ST	P18031	PTPN1	P06493	CDK1	S50	R45S	45	Missense	distal	-5	no	3.524	3.467	EPSD	ICGC	3.158	Down-regulation
CMGC_CDK_CDC2_CDK1_ST	Q96R06	SPAG5	P06493	CDK1	S12	L9F	9	Missense	distal	-3	no	3.675	3.679	EPSD	ICGC;COSMIC	3.158	Up-regulation
CMGC_CDK_CDC2_CDK1_ST	Q96R06	SPAG5	P06493	CDK1	T50	L53M	53	Missense	distal	3	no	3.032	3.177	EPSD	ICGC	3.158	Gain
CMGC_CDK_CDC2_CDK1_ST	Q96R06	SPAG5	P06493	CDK1	T50	L53P	53	Missense	distal	3	no	3.032	3.165	EPSD	ICGC;COSMIC	3.158	Gain
CMGC_CDK_CDC2_CDK1_ST	Q96R06	SPAG5	P06493	CDK1	T111	I105V	105	Missense	distal	-6	no	3.377	3.374	EPSD	ICGC;COSMIC	3.158	Down-regulation
CMGC_CDK_CDC2_CDK1_ST	Q96R06	SPAG5	P06493	CDK1	T111	P104T	104	Missense	distal	-7	no	3.377	3.438	EPSD	ICGC	3.158	Up-regulation
CMGC_CDK_CDC2_CDK1_ST	Q96R06	SPAG5	P06493	CDK1	T963	P964S	964	Missense	proximal	1	no	3.210	0.026	EPSD	ICGC;COSMIC	3.158	Loss
CMGC_CDK_CDC2_CDK1_ST	Q96R06	SPAG5	P06493	CDK1	T963	E962D	962	Missense	proximal	-1	no	3.210	3.202	EPSD	ICGC	3.158	Down-regulation
CMGC_CDK_CDC2_CDK1_ST	Q9NTI5	PDS5B	P06493	CDK1	T1220	K1218E	1218	Missense	proximal	-2	no	3.222	3.193	EPSD	ICGC	3.158	Down-regulation
CMGC_CDK_CDC2_CDK1_ST	Q9NTI5	PDS5B	P06493	CDK1	S1283	P1285S	1285	Missense	proximal	2	no	3.284	3.283	EPSD	ICGC;COSMIC	3.158	Down-regulation
CMGC_CDK_CDC2_CDK1_ST	Q9NTI5	PDS5B	P06493	CDK1	S1283	P1284Q	1284	Missense	proximal	1	no	3.284	0.862	EPSD	ICGC;COSMIC	3.158	Loss
CMGC_CDK_CDC2_CDK1_ST	Q9NTI5	PDS5B	P06493	CDK1	S1283	G1288V	1288	Missense	distal	5	no	3.284	3.252	EPSD	ICGC;COSMIC	3.158	Down-regulation
CMGC_CDK_CDC2_CDK1_ST	Q14CB8	ARHGAP19	P06493	CDK1	S470	R463M	463	Missense	distal	-7	no	3.384	3.353	EPSD	ICGC;COSMIC	3.158	Down-regulation
CMGC_CDK_CDC2_CDK1_ST	O14757	CHEK1	P06493	CDK1	T362	G364V	364	Missense	proximal	2	no	3.499	3.491	EPSD	ICGC;COSMIC	3.158	Down-regulation
CMGC_CDK_CDC2_CDK1_ST	P11171	EPB41	P06493	CDK1	T378	P379L	379	Missense	proximal	1	no	3.239	-0.448	EPSD	ICGC	3.158	Loss
CMGC_CDK_CDC2_CDK1_ST	P11171	EPB41	P06493	CDK1	T378	M377V	377	Missense	proximal	-1	no	3.239	3.296	EPSD	ICGC;COSMIC	3.158	Up-regulation
CMGC_CDK_CDC2_CDK1_ST	P11171	EPB41	P06493	CDK1	T378	M377I	377	Missense	proximal	-1	no	3.239	3.349	EPSD	ICGC	3.158	Up-regulation
CMGC_CDK_CDC2_CDK1_ST	Q9Y6I3	EPN1	P06493	CDK1	S536	P540A	540	Missense	distal	4	no	4.140	4.197	EPSD	ICGC;COSMIC	3.158	Up-regulation
CMGC_CDK_CDC2_CDK1_ST	Q9Y6I3	EPN1	P06493	CDK1	S536	P542S	542	Missense	distal	6	no	4.140	4.148	EPSD	ICGC;COSMIC	3.158	Up-regulation
CMGC_CDK_CDC2_CDK1_ST	Q9Y6I3	EPN1	P06493	CDK1	S536	R534C	534	Missense	proximal	-2	no	4.140	4.090	EPSD	ICGC;COSMIC	3.158	Down-regulation
CMGC_CDK_CDC2_CDK1_ST	Q92974	ARHGEF2	P06493	CDK1	S932	E935K	935	Missense	distal	3	no	3.444	3.548	EPSD	ICGC	3.158	Up-regulation
CMGC_CDK_CDC2_CDK1_ST	Q14202	ZMYM3	P06493	CDK1	S51	A46P	46	Missense	distal	-5	no	3.634	3.679	EPSD	ICGC;COSMIC	3.158	Up-regulation
CMGC_CDK_CDC2_CDK1_ST	Q14202	ZMYM3	P06493	CDK1	S51	A56D	56	Missense	distal	5	no	3.634	3.779	EPSD	ICGC	3.158	Up-regulation
CMGC_CDK_CDC2_CDK1_ST	Q14202	ZMYM3	P06493	CDK1	S51	G49V	49	Missense	proximal	-2	no	3.634	3.590	EPSD	ICGC;COSMIC	3.158	Down-regulation
CMGC_CDK_CDC2_CDK1_ST	Q14202	ZMYM3	P06493	CDK1	T62	A56D	56	Missense	distal	-6	no	3.497	3.509	EPSD	ICGC	3.158	Up-regulation
CMGC_CDK_CDC2_CDK1_ST	Q14202	ZMYM3	P06493	CDK1	T62	T62N	62	Missense	central	0	yes	3.497	0.000	EPSD	ICGC	3.158	Loss
CMGC_CDK_CDC2_CDK1_ST	Q14202	ZMYM3	P06493	CDK1	S91	P92S	92	Missense	proximal	1	no	3.201	0.016	EPSD	ICGC	3.158	Loss
CMGC_CDK_CDC2_CDK1_ST	Q14202	ZMYM3	P06493	CDK1	S154	P149L	149	Missense	distal	-5	no	3.181	3.302	EPSD	ICGC;COSMIC	3.158	Up-regulation
CMGC_CDK_CDC2_CDK1_ST	Q14202	ZMYM3	P06493	CDK1	S154	P155T	155	Missense	proximal	1	no	3.181	0.748	EPSD	ICGC;COSMIC	3.158	Loss
CMGC_CDK_CDC2_CDK1_ST	Q14202	ZMYM3	P06493	CDK1	S287	L292I	292	Missense	distal	5	no	3.232	3.183	EPSD	ICGC;COSMIC	3.158	Down-regulation
CMGC_CDK_CDC2_CDK1_ST	Q14202	ZMYM3	P06493	CDK1	S287	R289C	289	Missense	proximal	2	no	3.232	3.239	EPSD	ICGC	3.158	Up-regulation
CMGC_CDK_CDC2_CDK1_ST	Q14202	ZMYM3	P06493	CDK1	S464	G463E	463	Missense	proximal	-1	no	3.456	3.329	EPSD	ICGC;COSMIC	3.158	Down-regulation
CMGC_CDK_CDC2_CDK1_ST	P46060	RANGAP1	P06493	CDK1	T409	T409M	409	Missense	central	0	yes	3.255	0.000	PhosphoSitePlus	ICGC;COSMIC	3.158	Loss
CMGC_CDK_CDC2_CDK1_ST	P46060	RANGAP1	P06493	CDK1	T409	P410H	410	Missense	proximal	1	no	3.255	0.571	PhosphoSitePlus	ICGC	3.158	Loss
CMGC_CDK_CDC2_CDK1_ST	P46060	RANGAP1	P06493	CDK1	T409	R412W	412	Missense	distal	3	no	3.255	3.126	PhosphoSitePlus	ICGC;COSMIC;GDSC	3.158	Loss
CMGC_CDK_CDC2_CDK1_ST	P46060	RANGAP1	P06493	CDK1	T409	E405D	405	Missense	distal	-4	no	3.255	3.256	PhosphoSitePlus	ICGC	3.158	Up-regulation
CMGC_CDK_CDC2_CDK1_ST	P46060	RANGAP1	P06493	CDK1	T409	R412L	412	Missense	distal	3	no	3.255	3.002	PhosphoSitePlus	ICGC;COSMIC	3.158	Loss
CMGC_CDK_CDC2_CDK1_ST	Q9UQ35	SRRM2	P06493	CDK1	T9	R11L	11	Missense	proximal	2	no	3.143	3.158	EPSD	ICGC;COSMIC	3.158	Gain
CMGC_CDK_CDC2_CDK1_ST	Q9UQ35	SRRM2	P06493	CDK1	T111	V118F	118	Missense	distal	7	no	3.260	3.258	EPSD	ICGC	3.158	Down-regulation
CMGC_CDK_CDC2_CDK1_ST	Q9UQ35	SRRM2	P06493	CDK1	T111	G107S	107	Missense	distal	-4	no	3.260	3.397	EPSD	ICGC;COSMIC	3.158	Up-regulation
CMGC_CDK_CDC2_CDK1_ST	Q9UQ35	SRRM2	P06493	CDK1	S353	P354L	354	Missense	proximal	1	no	3.215	-0.471	EPSD	ICGC;COSMIC	3.158	Loss
CMGC_CDK_CDC2_CDK1_ST	Q9UQ35	SRRM2	P06493	CDK1	T651	S649Y	649	Missense	proximal	-2	no	3.117	3.167	EPSD	ICGC	3.158	Gain
CMGC_CDK_CDC2_CDK1_ST	Q9UQ35	SRRM2	P06493	CDK1	T946	R951I	951	Missense	distal	5	no	3.095	3.269	EPSD	ICGC	3.158	Gain
CMGC_CDK_CDC2_CDK1_ST	Q9UQ35	SRRM2	P06493	CDK1	S1311	S1318F	1318	Missense	distal	7	no	3.583	3.605	EPSD	ICGC;COSMIC	3.158	Up-regulation
CMGC_CDK_CDC2_CDK1_ST	Q9UQ35	SRRM2	P06493	CDK1	S1311	S1304F	1304	Missense	distal	-7	no	3.583	3.436	EPSD	ICGC	3.158	Down-regulation
CMGC_CDK_CDC2_CDK1_ST	Q9UQ35	SRRM2	P06493	CDK1	S1311	L1317M	1317	Missense	distal	6	no	3.583	3.624	EPSD	ICGC	3.158	Up-regulation
CMGC_CDK_CDC2_CDK1_ST	Q9UQ35	SRRM2	P06493	CDK1	S1311	G1306S	1306	Missense	distal	-5	no	3.583	3.457	EPSD	ICGC	3.158	Down-regulation
CMGC_CDK_CDC2_CDK1_ST	Q9UQ35	SRRM2	P06493	CDK1	S1320	S1318F	1318	Missense	proximal	-2	no	3.403	3.470	EPSD	ICGC;COSMIC	3.158	Up-regulation
CMGC_CDK_CDC2_CDK1_ST	Q9UQ35	SRRM2	P06493	CDK1	S1320	L1317M	1317	Missense	distal	-3	no	3.403	3.421	EPSD	ICGC	3.158	Up-regulation
CMGC_CDK_CDC2_CDK1_ST	Q9UQ35	SRRM2	P06493	CDK1	S1713	R1717C	1717	Missense	distal	4	no	3.161	3.097	EPSD	ICGC;COSMIC	3.158	Loss
CMGC_CDK_CDC2_CDK1_ST	Q9UQ35	SRRM2	P06493	CDK1	S1713	S1707R	1707	Missense	distal	-6	no	3.161	3.168	EPSD	ICGC;COSMIC	3.158	Up-regulation
CMGC_CDK_CDC2_CDK1_ST	Q9UQ35	SRRM2	P06493	CDK1	S1713	R1708H	1708	Missense	distal	-5	no	3.161	3.156	EPSD	ICGC;COSMIC	3.158	Loss
CMGC_CDK_CDC2_CDK1_ST	Q9UQ35	SRRM2	P06493	CDK1	T2144	Q2150H	2150	Missense	distal	6	no	3.308	3.307	EPSD	ICGC	3.158	Down-regulation
CMGC_CDK_CDC2_CDK1_ST	Q9UQ35	SRRM2	P06493	CDK1	T2738	R2742W	2742	Missense	distal	4	no	3.235	3.162	EPSD	ICGC;COSMIC	3.158	Down-regulation
CMGC_CDK_CDC2_CDK1_ST	Q9UQ35	SRRM2	P06493	CDK1	S2751	R2750S	2750	Missense	proximal	-1	no	3.174	3.112	EPSD	ICGC	3.158	Loss
CMGC_CDK_CDC2_CDK1_ST	P30260	CDC27	P06493	CDK1	T68	Y73C	73	Missense	distal	5	no	3.903	3.883	EPSD	ICGC;COSMIC	3.158	Down-regulation
CMGC_CDK_CDC2_CDK1_ST	P30260	CDC27	P06493	CDK1	T68	T67P	67	Missense	proximal	-1	no	3.903	3.982	EPSD	ICGC;COSMIC	3.158	Up-regulation
CMGC_CDK_CDC2_CDK1_ST	P30260	CDC27	P06493	CDK1	T68	P69L	69	Missense	proximal	1	no	3.903	0.217	EPSD	ICGC;COSMIC	3.158	Loss
CMGC_CDK_CDC2_CDK1_ST	P30260	CDC27	P06493	CDK1	S237	I235T	235	Missense	proximal	-2	no	3.400	3.267	EPSD	ICGC;COSMIC	3.158	Down-regulation
CMGC_CDK_CDC2_CDK1_ST	P30260	CDC27	P06493	CDK1	S237	Y234S	234	Missense	distal	-3	no	3.400	3.433	EPSD	ICGC;COSMIC	3.158	Up-regulation
CMGC_CDK_CDC2_CDK1_ST	P30260	CDC27	P06493	CDK1	S237	S231P	231	Missense	distal	-6	no	3.400	3.402	EPSD	ICGC;COSMIC	3.158	Up-regulation
CMGC_CDK_CDC2_CDK1_ST	P30260	CDC27	P06493	CDK1	S237	P242S	242	Missense	distal	5	no	3.400	3.372	EPSD	ICGC;COSMIC	3.158	Down-regulation
CMGC_CDK_CDC2_CDK1_ST	P30260	CDC27	P06493	CDK1	S237	S230Y	230	Missense	distal	-7	no	3.400	3.285	EPSD	ICGC;COSMIC	3.158	Down-regulation
CMGC_CDK_CDC2_CDK1_ST	P30260	CDC27	P06493	CDK1	T279	A273G	273	Missense	distal	-6	no	3.140	3.165	EPSD	ICGC;COSMIC	3.158	Gain
CMGC_CDK_CDC2_CDK1_ST	P30260	CDC27	P06493	CDK1	T279	L275V	275	Missense	distal	-4	no	3.140	3.213	EPSD	ICGC;COSMIC	3.158	Gain
CMGC_CDK_CDC2_CDK1_ST	P30260	CDC27	P06493	CDK1	T279	A274D	274	Missense	distal	-5	no	3.140	3.208	EPSD	ICGC;COSMIC	3.158	Gain
CMGC_CDK_CDC2_CDK1_ST	P30260	CDC27	P06493	CDK1	T279	A274S	274	Missense	distal	-5	no	3.140	3.164	EPSD	ICGC;COSMIC	3.158	Gain
CMGC_CDK_CDC2_CDK1_ST	P30260	CDC27	P06493	CDK1	T279	G283W	283	Missense	distal	4	no	3.140	3.193	EPSD	ICGC;COSMIC	3.158	Gain
CMGC_CDK_CDC2_CDK1_ST	P30260	CDC27	P06493	CDK1	T279	F282S	282	Missense	distal	3	no	3.140	3.271	EPSD	ICGC;COSMIC	3.158	Gain
CMGC_CDK_CDC2_CDK1_ST	P30260	CDC27	P06493	CDK1	S369	R376Q	376	Missense	distal	7	no	3.327	3.322	EPSD	ICGC;COSMIC	3.158	Down-regulation
CMGC_CDK_CDC2_CDK1_ST	P30260	CDC27	P06493	CDK1	S369	I367M	367	Missense	proximal	-2	no	3.327	3.251	EPSD	ICGC;COSMIC	3.158	Down-regulation
CMGC_CDK_CDC2_CDK1_ST	P30260	CDC27	P06493	CDK1	S369	P375H	375	Missense	distal	6	no	3.327	3.322	EPSD	ICGC	3.158	Down-regulation
CMGC_CDK_CDC2_CDK1_ST	P30260	CDC27	P06493	CDK1	S369	T368I	368	Missense	proximal	-1	no	3.327	3.553	EPSD	ICGC	3.158	Up-regulation
CMGC_CDK_CDC2_CDK1_ST	P30260	CDC27	P06493	CDK1	S369	A373T	373	Missense	distal	4	no	3.327	3.275	EPSD	ICGC;COSMIC;CCLE	3.158	Down-regulation
CMGC_CDK_CDC2_CDK1_ST	P30260	CDC27	P06493	CDK1	S369	V362I	362	Missense	distal	-7	no	3.327	3.300	EPSD	ICGC;COSMIC	3.158	Down-regulation
CMGC_CDK_CDC2_CDK1_ST	P30260	CDC27	P06493	CDK1	T446	G440E	440	Missense	distal	-6	no	3.311	3.297	EPSD;PhosphoSitePlus	ICGC;COSMIC	3.158	Down-regulation
CMGC_CDK_CDC2_CDK1_ST	P30260	CDC27	P06493	CDK1	T446	K441E	441	Missense	distal	-5	no	3.311	3.280	EPSD;PhosphoSitePlus	ICGC	3.158	Down-regulation
CMGC_CDK_CDC2_CDK1_ST	P30260	CDC27	P06493	CDK1	T446	T444A	444	Missense	proximal	-2	no	3.311	3.230	EPSD;PhosphoSitePlus	ICGC;COSMIC	3.158	Down-regulation
CMGC_CDK_CDC2_CDK1_ST	P30260	CDC27	P06493	CDK1	T446	T446A	446	Missense	central	0	yes	3.311	0.000	EPSD;PhosphoSitePlus	ICGC;COSMIC	3.158	Loss
CMGC_CDK_CDC2_CDK1_ST	P17302	GJA1	P06493	CDK1	S279	G285V	285	Missense	distal	6	no	3.531	3.547	EPSD	ICGC;COSMIC	3.158	Up-regulation
CMGC_CDK_CDC2_CDK1_ST	P17302	GJA1	P06493	CDK1	S279	P284L	284	Missense	distal	5	no	3.531	3.716	EPSD	ICGC	3.158	Up-regulation
CMGC_CDK_CDC2_CDK1_ST	P46937	YAP1	P06493	CDK1	T143	V137F	137	Missense	distal	-6	no	3.701	3.706	EPSD;PhosphoSitePlus	ICGC;COSMIC	3.158	Up-regulation
CMGC_CDK_CDC2_CDK1_ST	P46937	YAP1	P06493	CDK1	T143	T145N	145	Missense	proximal	2	no	3.701	3.707	EPSD;PhosphoSitePlus	ICGC	3.158	Up-regulation
CMGC_CDK_CDC2_CDK1_ST	P38936	CDKN1A	P06493	CDK1	T57	D52N	52	Missense	distal	-5	no	3.807	3.810	EPSD	ICGC;COSMIC	3.158	Up-regulation
CMGC_CDK_CDC2_CDK1_ST	P38936	CDKN1A	P06493	CDK1	T57	E56D	56	Missense	proximal	-1	no	3.807	3.799	EPSD	ICGC	3.158	Down-regulation
CMGC_CDK_CDC2_CDK1_ST	P38936	CDKN1A	P06493	CDK1	T57	F51V	51	Missense	distal	-6	no	3.807	3.802	EPSD	ICGC;COSMIC	3.158	Down-regulation
CMGC_CDK_CDC2_CDK1_ST	Q32P44	EML3	P06493	CDK1	S198	P202T	202	Missense	distal	4	no	3.331	3.335	EPSD	ICGC;COSMIC	3.158	Up-regulation
CMGC_CDK_CDC2_CDK1_ST	Q32P44	EML3	P06493	CDK1	S198	P202L	202	Missense	distal	4	no	3.331	3.208	EPSD	ICGC;COSMIC	3.158	Down-regulation
CMGC_CDK_CDC2_CDK1_ST	Q9H1A4	ANAPC1	P06493	CDK1	T221	P222S	222	Missense	proximal	1	no	3.178	-0.007	EPSD	ICGC	3.158	Loss
CMGC_CDK_CDC2_CDK1_ST	Q9H1A4	ANAPC1	P06493	CDK1	T291	Q288H	288	Missense	distal	-3	no	3.507	3.495	EPSD;PhosphoSitePlus	ICGC	3.158	Down-regulation
CMGC_CDK_CDC2_CDK1_ST	Q9H1A4	ANAPC1	P06493	CDK1	S377	P378S	378	Missense	proximal	1	no	3.324	0.140	EPSD;PhosphoSitePlus	ICGC	3.158	Loss
CMGC_CDK_CDC2_CDK1_ST	Q9H1A4	ANAPC1	P06493	CDK1	S555	P556Q	556	Missense	proximal	1	no	3.424	1.001	EPSD;PhosphoSitePlus	ICGC	3.158	Loss
CMGC_CDK_CDC2_CDK1_ST	P23443	RPS6KB1	P06493	CDK1	S434	S441N	441	Missense	distal	7	no	3.847	3.854	EPSD;PhosphoSitePlus	ICGC;COSMIC	3.158	Up-regulation
CMGC_CDK_CDC2_CDK1_ST	Q8IZD2	KMT2E	P06493	CDK1	T904	P908T	908	Missense	distal	4	no	3.351	3.355	EPSD	ICGC;COSMIC	3.158	Up-regulation
CMGC_CDK_CDC2_CDK1_ST	Q8IZD2	KMT2E	P06493	CDK1	T904	P898L	898	Missense	distal	-6	no	3.351	3.378	EPSD	ICGC;COSMIC	3.158	Up-regulation
CMGC_CDK_CDC2_CDK1_ST	Q8IZD2	KMT2E	P06493	CDK1	T904	M906L	906	Missense	proximal	2	no	3.351	3.365	EPSD	ICGC;COSMIC	3.158	Up-regulation
CMGC_CDK_CDC2_CDK1_ST	Q8IZD2	KMT2E	P06493	CDK1	S1070	S1065F	1065	Missense	distal	-5	no	3.197	3.306	EPSD	ICGC;COSMIC	3.158	Up-regulation
CMGC_CDK_CDC2_CDK1_ST	Q8IZD2	KMT2E	P06493	CDK1	T1088	T1088A	1088	Missense	central	0	yes	3.506	0.000	EPSD	ICGC;COSMIC	3.158	Loss
CMGC_CDK_CDC2_CDK1_ST	Q8IZD2	KMT2E	P06493	CDK1	T1147	Q1149K	1149	Missense	proximal	2	no	3.525	3.527	EPSD	ICGC;COSMIC	3.158	Up-regulation
CMGC_CDK_CDC2_CDK1_ST	P12270	TPR	P06493	CDK1	T653	S652F	652	Missense	proximal	-1	no	3.119	3.273	EPSD	ICGC;COSMIC	3.158	Gain
CMGC_CDK_CDC2_CDK1_ST	Q02880	TOP2B	P06493	CDK1	T1431	P1432S	1432	Missense	proximal	1	no	3.718	0.533	EPSD	ICGC	3.158	Loss
CMGC_CDK_CDC2_CDK1_ST	Q7Z3J3	RGPD4	P06493	CDK1	T1153	R1146Q	1146	Missense	distal	-7	no	3.371	3.377	EPSD	ICGC;COSMIC	3.158	Up-regulation
CMGC_CDK_CDC2_CDK1_ST	Q7Z3J3	RGPD4	P06493	CDK1	T1153	F1151L	1151	Missense	proximal	-2	no	3.371	3.350	EPSD	ICGC;COSMIC	3.158	Down-regulation
CMGC_CDK_CDC2_CDK1_ST	Q7Z3J3	RGPD4	P06493	CDK1	T1153	A1157D	1157	Missense	distal	4	no	3.371	3.267	EPSD	ICGC	3.158	Down-regulation
CMGC_CDK_CDC2_CDK1_ST	Q7Z3J3	RGPD4	P06493	CDK1	S1305	S1301I	1301	Missense	distal	-4	no	3.498	3.355	EPSD	ICGC;COSMIC	3.158	Down-regulation
CMGC_CDK_CDC2_CDK1_ST	Q7Z3J3	RGPD4	P06493	CDK1	S1743	T1738M	1738	Missense	distal	-5	no	3.302	3.359	EPSD	ICGC	3.158	Up-regulation
CMGC_CDK_CDC2_CDK1_ST	Q16659	MAPK6	P06493	CDK1	T698	T696R	696	Missense	proximal	-2	no	3.066	3.172	EPSD;PhosphoSitePlus	ICGC;COSMIC	3.158	Gain
CMGC_CDK_CDC2_CDK1_ST	Q16659	MAPK6	P06493	CDK1	S705	I708S	708	Missense	distal	3	no	3.186	3.283	EPSD;PhosphoSitePlus	ICGC;COSMIC	3.158	Up-regulation
CMGC_CDK_CDC2_CDK1_ST	Q16659	MAPK6	P06493	CDK1	S705	M702I	702	Missense	distal	-3	no	3.186	3.159	EPSD;PhosphoSitePlus	ICGC;COSMIC	3.158	Down-regulation
CMGC_CDK_CDC2_CDK1_ST	Q16659	MAPK6	P06493	CDK1	S705	P706S	706	Missense	proximal	1	no	3.186	0.002	EPSD;PhosphoSitePlus	ICGC;COSMIC	3.158	Loss
CMGC_CDK_CDC2_CDK1_ST	Q13428	TCOF1	P06493	CDK1	S233	A238V	238	Missense	distal	5	no	3.648	3.855	EPSD	ICGC	3.158	Up-regulation
CMGC_CDK_CDC2_CDK1_ST	Q13428	TCOF1	P06493	CDK1	S503	A509S	509	Missense	distal	6	no	3.578	3.568	EPSD	ICGC;COSMIC	3.158	Down-regulation
CMGC_CDK_CDC2_CDK1_ST	Q13428	TCOF1	P06493	CDK1	S503	V506M	506	Missense	distal	3	no	3.578	3.640	EPSD	ICGC;COSMIC	3.158	Up-regulation
CMGC_CDK_CDC2_CDK1_ST	Q01581	HMGCS1	P06493	CDK1	T471	R464T	464	Missense	distal	-7	no	3.222	3.279	EPSD	ICGC;COSMIC	3.158	Up-regulation
CMGC_CDK_CDC2_CDK1_ST	Q01581	HMGCS1	P06493	CDK1	T471	P472T	472	Missense	proximal	1	no	3.222	0.789	EPSD	ICGC;COSMIC	3.158	Loss
CMGC_CDK_CDC2_CDK1_ST	Q96GX5	MASTL	P06493	CDK1	T207	P208T	208	Missense	proximal	1	no	3.549	1.116	EPSD	ICGC;COSMIC	3.158	Loss
CMGC_CDK_CDC2_CDK1_ST	Q96GX5	MASTL	P06493	CDK1	T261	T261M	261	Missense	central	0	yes	3.352	0.000	EPSD	ICGC;COSMIC	3.158	Loss
CMGC_CDK_CDC2_CDK1_ST	Q96GX5	MASTL	P06493	CDK1	S453	E448K	448	Missense	distal	-5	no	3.169	3.199	EPSD	ICGC;COSMIC	3.158	Up-regulation
CMGC_CDK_CDC2_CDK1_ST	Q96GX5	MASTL	P06493	CDK1	T722	R727T	727	Missense	distal	5	no	3.459	3.474	EPSD	ICGC;COSMIC	3.158	Up-regulation
CMGC_CDK_CDC2_CDK1_ST	P50570	DNM2	P06493	CDK1	S116	P119L	119	Missense	distal	3	no	3.426	3.293	EPSD	ICGC;COSMIC	3.158	Down-regulation
CMGC_CDK_CDC2_CDK1_ST	P50570	DNM2	P06493	CDK1	S126	V124L	124	Missense	proximal	-2	no	3.421	3.423	EPSD	ICGC;COSMIC	3.158	Up-regulation
CMGC_CDK_CDC2_CDK1_ST	P50570	DNM2	P06493	CDK1	S126	P119L	119	Missense	distal	-7	no	3.421	3.261	EPSD	ICGC;COSMIC	3.158	Down-regulation
CMGC_CDK_CDC2_CDK1_ST	P50570	DNM2	P06493	CDK1	T404	T404N	404	Missense	central	0	yes	3.627	0.000	EPSD	ICGC;COSMIC	3.158	Loss
CMGC_CDK_CDC2_CDK1_ST	P50570	DNM2	P06493	CDK1	T404	E410K	410	Missense	distal	6	no	3.627	3.629	EPSD	ICGC;COSMIC	3.158	Up-regulation
CMGC_CDK_CDC2_CDK1_ST	P50570	DNM2	P06493	CDK1	T404	R399S	399	Missense	distal	-5	no	3.627	3.569	EPSD	ICGC	3.158	Down-regulation
CMGC_CDK_CDC2_CDK1_ST	P50570	DNM2	P06493	CDK1	T404	P405L	405	Missense	proximal	1	no	3.627	-0.060	EPSD	ICGC;COSMIC;GDSC;CCLE	3.158	Loss
CMGC_CDK_CDC2_CDK1_ST	P50570	DNM2	P06493	CDK1	T404	P405H	405	Missense	proximal	1	no	3.627	0.942	EPSD	ICGC;COSMIC	3.158	Loss
CMGC_CDK_CDC2_CDK1_ST	P50570	DNM2	P06493	CDK1	T404	G401R	401	Missense	distal	-3	no	3.627	3.654	EPSD	ICGC	3.158	Up-regulation
CMGC_CDK_CDC2_CDK1_ST	O94761	RECQL4	P06493	CDK1	T93	Q91K	91	Missense	proximal	-2	no	3.723	3.778	EPSD	ICGC	3.158	Up-regulation
CMGC_CDK_CDC2_CDK1_ST	O94761	RECQL4	P06493	CDK1	T93	R96L	96	Missense	distal	3	no	3.723	3.470	EPSD	ICGC;COSMIC	3.158	Down-regulation
CMGC_CDK_CDC2_CDK1_ST	Q8WUF5	PPP1R13L	P06493	CDK1	T95	R99Q	99	Missense	distal	4	no	3.180	3.162	EPSD	ICGC	3.158	Down-regulation
CMGC_CDK_CDC2_CDK1_ST	Q8WUF5	PPP1R13L	P06493	CDK1	T95	A93T	93	Missense	proximal	-2	no	3.180	3.261	EPSD	ICGC;COSMIC	3.158	Up-regulation
CMGC_CDK_CDC2_CDK1_ST	Q8WUF5	PPP1R13L	P06493	CDK1	T95	A88E	88	Missense	distal	-7	no	3.180	3.086	EPSD	ICGC;COSMIC	3.158	Loss
CMGC_CDK_CDC2_CDK1_ST	Q8WUF5	PPP1R13L	P06493	CDK1	T173	D176V	176	Missense	distal	3	no	3.266	3.235	EPSD	ICGC;COSMIC	3.158	Down-regulation
CMGC_CDK_CDC2_CDK1_ST	Q8WUF5	PPP1R13L	P06493	CDK1	S187	R185H	185	Missense	proximal	-2	no	3.223	3.177	EPSD	ICGC	3.158	Down-regulation
CMGC_CDK_CDC2_CDK1_ST	Q8WUF5	PPP1R13L	P06493	CDK1	S187	E191K	191	Missense	distal	4	no	3.223	3.254	EPSD	ICGC;COSMIC	3.158	Up-regulation
CMGC_CDK_CDC2_CDK1_ST	Q8WUF5	PPP1R13L	P06493	CDK1	S187	G192E	192	Missense	distal	5	no	3.223	3.121	EPSD	ICGC;COSMIC	3.158	Loss
CMGC_CDK_CDC2_CDK1_ST	Q8WUF5	PPP1R13L	P06493	CDK1	S280	S282R	282	Missense	proximal	2	no	3.158	3.165	EPSD	ICGC	3.158	Up-regulation
CMGC_CDK_CDC2_CDK1_ST	Q8WUF5	PPP1R13L	P06493	CDK1	S280	Q284L	284	Missense	distal	4	no	3.158	3.040	EPSD	ICGC	3.158	Loss
CMGC_CDK_CDC2_CDK1_ST	Q8WUF5	PPP1R13L	P06493	CDK1	S280	P281Q	281	Missense	proximal	1	no	3.158	0.736	EPSD	ICGC;COSMIC	3.158	Loss
CMGC_CDK_CDC2_CDK1_ST	Q8WUF5	PPP1R13L	P06493	CDK1	S616	R612L	612	Missense	distal	-4	no	3.554	3.426	EPSD	ICGC;COSMIC	3.158	Down-regulation
CMGC_CDK_CDC2_CDK1_ST	A6NKT7	RGPD3	P06493	CDK1	T1412	S1416G	1416	Missense	distal	4	no	3.322	3.214	EPSD	ICGC;COSMIC	3.158	Down-regulation
CMGC_CDK_CDC2_CDK1_ST	A6NKT7	RGPD3	P06493	CDK1	S1487	G1490D	1490	Missense	distal	3	no	3.270	3.323	EPSD	ICGC	3.158	Up-regulation
CMGC_CDK_CDC2_CDK1_ST	A6NKT7	RGPD3	P06493	CDK1	T1638	P1643H	1643	Missense	distal	5	no	3.471	3.498	EPSD	ICGC	3.158	Up-regulation
CMGC_CDK_CDC2_CDK1_ST	A6NKT7	RGPD3	P06493	CDK1	T1638	P1643T	1643	Missense	distal	5	no	3.471	3.449	EPSD	ICGC	3.158	Down-regulation
CMGC_CDK_CDC2_CDK1_ST	Q9UPP1	PHF8	P06493	CDK1	S880	D876V	876	Missense	distal	-4	no	3.385	3.322	EPSD	ICGC;COSMIC	3.158	Down-regulation
CMGC_CDK_CDC2_CDK1_ST	Q12778	FOXO1	P06493	CDK1	S329	E334K	334	Missense	distal	5	no	3.261	3.213	EPSD	ICGC;COSMIC;CCLE	3.158	Down-regulation
CMGC_CDK_CDC2_CDK1_ST	Q12778	FOXO1	P06493	CDK1	S329	G326V	326	Missense	distal	-3	no	3.261	3.296	EPSD	ICGC;COSMIC	3.158	Up-regulation
CMGC_CDK_CDC2_CDK1_ST	Q12778	FOXO1	P06493	CDK1	S394	Q392K	392	Missense	proximal	-2	no	3.109	3.163	EPSD	ICGC	3.158	Gain
CMGC_CDK_CDC2_CDK1_ST	Q86WB0	ZC3HC1	P06493	CDK1	S24	T28N	28	Missense	distal	4	no	3.407	3.381	EPSD	ICGC	3.158	Down-regulation
CMGC_CDK_CDC2_CDK1_ST	Q86WB0	ZC3HC1	P06493	CDK1	S62	G61E	61	Missense	proximal	-1	no	3.312	3.185	EPSD	ICGC;COSMIC	3.158	Down-regulation
CMGC_CDK_CDC2_CDK1_ST	Q86WB0	ZC3HC1	P06493	CDK1	S62	Q67K	67	Missense	distal	5	no	3.312	3.330	EPSD	ICGC	3.158	Up-regulation
CMGC_CDK_CDC2_CDK1_ST	O95235	KIF20A	P06493	CDK1	S7	L12F	12	Missense	distal	5	no	3.362	3.316	EPSD;PhosphoSitePlus	ICGC	3.158	Down-regulation
CMGC_CDK_CDC2_CDK1_ST	O95235	KIF20A	P06493	CDK1	S7	G11C	11	Missense	distal	4	no	3.362	3.423	EPSD;PhosphoSitePlus	ICGC	3.158	Up-regulation
CMGC_CDK_CDC2_CDK1_ST	O95235	KIF20A	P06493	CDK1	S7	I5V	5	Missense	proximal	-2	no	3.362	3.314	EPSD;PhosphoSitePlus	ICGC;COSMIC	3.158	Down-regulation
CMGC_CDK_CDC2_CDK1_ST	O95235	KIF20A	P06493	CDK1	S7	S7Y	7	Missense	central	0	yes	3.362	0.000	EPSD;PhosphoSitePlus	ICGC;COSMIC	3.158	Loss
CMGC_CDK_CDC2_CDK1_ST	O95235	KIF20A	P06493	CDK1	S867	S863T	863	Missense	distal	-4	no	3.385	3.394	PhosphoSitePlus;EPSD	ICGC;COSMIC	3.158	Up-regulation
CMGC_CDK_CDC2_CDK1_ST	P30304	CDC25A	P06493	CDK1	S261	S263F	263	Missense	proximal	2	no	3.152	3.174	EPSD	ICGC	3.158	Gain
CMGC_CDK_CDC2_CDK1_ST	P30304	CDC25A	P06493	CDK1	S321	S317Y	317	Missense	distal	-4	no	3.190	3.091	EPSD	ICGC	3.158	Loss
CMGC_CDK_CDC2_CDK1_ST	P30304	CDC25A	P06493	CDK1	S321	S315Y	315	Missense	distal	-6	no	3.190	3.207	EPSD	ICGC	3.158	Up-regulation
CMGC_CDK_CDC2_CDK1_ST	P30304	CDC25A	P06493	CDK1	S321	A319E	319	Missense	proximal	-2	no	3.190	3.348	EPSD	ICGC;COSMIC	3.158	Up-regulation
CMGC_CDK_CDC2_CDK1_ST	P30304	CDC25A	P06493	CDK1	S321	G324R	324	Missense	distal	3	no	3.190	3.383	EPSD	ICGC	3.158	Up-regulation
CMGC_CDK_CDC2_CDK1_ST	Q15398	DLGAP5	P06493	CDK1	T338	R331K	331	Missense	distal	-7	no	3.161	3.084	EPSD	ICGC;COSMIC	3.158	Loss
CMGC_CDK_CDC2_CDK1_ST	Q15398	DLGAP5	P06493	CDK1	T338	P345S	345	Missense	distal	7	no	3.161	3.159	EPSD	ICGC	3.158	Down-regulation
CMGC_CDK_CDC2_CDK1_ST	Q15398	DLGAP5	P06493	CDK1	T344	V350A	350	Missense	distal	6	no	3.371	3.419	EPSD	ICGC;COSMIC	3.158	Up-regulation
CMGC_CDK_CDC2_CDK1_ST	Q15398	DLGAP5	P06493	CDK1	T344	P345S	345	Missense	proximal	1	no	3.371	0.186	EPSD	ICGC	3.158	Loss
CMGC_CDK_CDC2_CDK1_ST	Q15398	DLGAP5	P06493	CDK1	T639	K641T	641	Missense	proximal	2	no	3.313	3.308	EPSD;PhosphoSitePlus	ICGC;COSMIC	3.158	Down-regulation
CMGC_CDK_CDC2_CDK1_ST	P52948	NUP98	P06493	CDK1	S839	D845A	845	Missense	distal	6	no	3.422	3.456	EPSD	ICGC;COSMIC	3.158	Up-regulation
CMGC_CDK_CDC2_CDK1_ST	P52948	NUP98	P06493	CDK1	S839	T832I	832	Missense	distal	-7	no	3.422	3.249	EPSD	ICGC;COSMIC	3.158	Down-regulation
CMGC_CDK_CDC2_CDK1_ST	Q12888	TP53BP1	P06493	CDK1	S265	P266H	266	Missense	proximal	1	no	3.373	0.689	EPSD	ICGC;COSMIC	3.158	Loss
CMGC_CDK_CDC2_CDK1_ST	Q12888	TP53BP1	P06493	CDK1	S265	E260G	260	Missense	distal	-5	no	3.373	3.446	EPSD	ICGC;COSMIC	3.158	Up-regulation
CMGC_CDK_CDC2_CDK1_ST	Q12888	TP53BP1	P06493	CDK1	S265	V270A	270	Missense	distal	5	no	3.373	3.166	EPSD	ICGC	3.158	Down-regulation
CMGC_CDK_CDC2_CDK1_ST	Q12888	TP53BP1	P06493	CDK1	T334	A336D	336	Missense	proximal	2	no	3.504	3.520	EPSD	ICGC	3.158	Up-regulation
CMGC_CDK_CDC2_CDK1_ST	Q12888	TP53BP1	P06493	CDK1	T334	P335T	335	Missense	proximal	1	no	3.504	1.070	EPSD	ICGC	3.158	Loss
CMGC_CDK_CDC2_CDK1_ST	Q12888	TP53BP1	P06493	CDK1	T334	P335S	335	Missense	proximal	1	no	3.504	0.319	EPSD	ICGC;COSMIC	3.158	Loss
CMGC_CDK_CDC2_CDK1_ST	Q12888	TP53BP1	P06493	CDK1	T334	L339V	339	Missense	distal	5	no	3.504	3.440	EPSD	ICGC;COSMIC	3.158	Down-regulation
CMGC_CDK_CDC2_CDK1_ST	Q12888	TP53BP1	P06493	CDK1	T334	G327V	327	Missense	distal	-7	no	3.504	3.537	EPSD	ICGC;COSMIC	3.158	Up-regulation
CMGC_CDK_CDC2_CDK1_ST	Q12888	TP53BP1	P06493	CDK1	T334	G328W	328	Missense	distal	-6	no	3.504	3.496	EPSD	ICGC;COSMIC	3.158	Down-regulation
CMGC_CDK_CDC2_CDK1_ST	Q12888	TP53BP1	P06493	CDK1	S525	P526Q	526	Missense	proximal	1	no	3.159	0.737	EPSD	ICGC;COSMIC	3.158	Loss
CMGC_CDK_CDC2_CDK1_ST	Q12888	TP53BP1	P06493	CDK1	S525	M528I	528	Missense	distal	3	no	3.159	3.101	EPSD	ICGC;COSMIC	3.158	Loss
CMGC_CDK_CDC2_CDK1_ST	Q12888	TP53BP1	P06493	CDK1	S525	S523N	523	Missense	proximal	-2	no	3.159	3.189	EPSD	ICGC	3.158	Up-regulation
CMGC_CDK_CDC2_CDK1_ST	Q12888	TP53BP1	P06493	CDK1	S525	K527N	527	Missense	proximal	2	no	3.159	3.160	EPSD	ICGC;COSMIC	3.158	Up-regulation
CMGC_CDK_CDC2_CDK1_ST	Q12888	TP53BP1	P06493	CDK1	S630	S635F	635	Missense	distal	5	no	3.101	3.268	EPSD	ICGC;COSMIC	3.158	Gain
CMGC_CDK_CDC2_CDK1_ST	Q12888	TP53BP1	P06493	CDK1	S630	P629L	629	Missense	proximal	-1	no	3.101	3.251	EPSD	ICGC;COSMIC	3.158	Gain
CMGC_CDK_CDC2_CDK1_ST	Q12888	TP53BP1	P06493	CDK1	S727	I733T	733	Missense	distal	6	no	3.111	3.163	EPSD	ICGC;COSMIC	3.158	Gain
CMGC_CDK_CDC2_CDK1_ST	Q12888	TP53BP1	P06493	CDK1	S1028	A1027S	1027	Missense	proximal	-1	no	3.299	3.352	EPSD	ICGC;COSMIC	3.158	Up-regulation
CMGC_CDK_CDC2_CDK1_ST	Q12888	TP53BP1	P06493	CDK1	S1101	S1101Y	1101	Missense	central	0	yes	3.297	0.000	EPSD	ICGC;COSMIC	3.158	Loss
CMGC_CDK_CDC2_CDK1_ST	Q12888	TP53BP1	P06493	CDK1	S1288	C1283R	1283	Missense	distal	-5	no	3.678	3.645	EPSD	ICGC;COSMIC	3.158	Down-regulation
CMGC_CDK_CDC2_CDK1_ST	Q12888	TP53BP1	P06493	CDK1	S1354	R1355P	1355	Missense	proximal	1	no	-0.440	3.169	EPSD	ICGC;COSMIC	3.158	Gain
CMGC_CDK_CDC2_CDK1_ST	Q12888	TP53BP1	P06493	CDK1	S1362	R1355P	1355	Missense	distal	-7	no	3.878	3.874	EPSD	ICGC;COSMIC	3.158	Down-regulation
CMGC_CDK_CDC2_CDK1_ST	Q12888	TP53BP1	P06493	CDK1	T1372	T1370K	1370	Missense	proximal	-2	no	3.137	3.243	EPSD	ICGC;COSMIC	3.158	Gain
CMGC_CDK_CDC2_CDK1_ST	Q12888	TP53BP1	P06493	CDK1	T1638	P1636S	1636	Missense	proximal	-2	no	3.152	3.278	EPSD	ICGC;COSMIC	3.158	Gain
CMGC_CDK_CDC2_CDK1_ST	Q12888	TP53BP1	P06493	CDK1	S1678	R1684H	1684	Missense	distal	6	no	3.993	3.975	PhosphoSitePlus;EPSD	ICGC;COSMIC	3.158	Down-regulation
CMGC_CDK_CDC2_CDK1_ST	Q12888	TP53BP1	P06493	CDK1	S1678	E1676K	1676	Missense	proximal	-2	no	3.993	4.022	PhosphoSitePlus;EPSD	ICGC;COSMIC	3.158	Up-regulation
CMGC_CDK_CDC2_CDK1_ST	Q12888	TP53BP1	P06493	CDK1	S1678	R1684C	1684	Missense	distal	6	no	3.993	3.956	PhosphoSitePlus;EPSD	ICGC;COSMIC	3.158	Down-regulation
CMGC_CDK_CDC2_CDK1_ST	Q12888	TP53BP1	P06493	CDK1	S1678	R1677W	1677	Missense	proximal	-1	no	3.993	4.065	PhosphoSitePlus;EPSD	ICGC;COSMIC	3.158	Up-regulation
CMGC_CDK_CDC2_CDK1_ST	Q12888	TP53BP1	P06493	CDK1	S1678	R1677Q	1677	Missense	proximal	-1	no	3.993	3.982	PhosphoSitePlus;EPSD	ICGC;COSMIC	3.158	Down-regulation
CMGC_CDK_CDC2_CDK1_ST	O15350	TP73	P06493	CDK1	T167	P168L	168	Missense	proximal	1	no	3.416	-0.270	EPSD	ICGC;COSMIC	3.158	Loss
CMGC_CDK_CDC2_CDK1_ST	O15350	TP73	P06493	CDK1	T167	P160S	160	Missense	distal	-7	no	3.416	3.456	EPSD	ICGC	3.158	Up-regulation
CMGC_CDK_CDC2_CDK1_ST	O15350	TP73	P06493	CDK1	S333	V337I	337	Missense	distal	4	no	3.491	3.472	EPSD	ICGC;COSMIC	3.158	Down-regulation
CMGC_CDK_CDC2_CDK1_ST	O15350	TP73	P06493	CDK1	S333	K331N	331	Missense	proximal	-2	no	3.491	3.453	EPSD	ICGC	3.158	Down-regulation
CMGC_CDK_CDC2_CDK1_ST	O15350	TP73	P06493	CDK1	S333	A336S	336	Missense	distal	3	no	3.491	3.438	EPSD	ICGC;COSMIC	3.158	Down-regulation
CMGC_CDK_CDC2_CDK1_ST	O15350	TP73	P06493	CDK1	S412	P413S	413	Missense	proximal	1	no	3.757	0.572	EPSD	ICGC;COSMIC	3.158	Loss
CMGC_CDK_CDC2_CDK1_ST	Q09666	AHNAK	P06493	CDK1	S93	R88P	88	Missense	distal	-5	no	3.165	3.130	EPSD	ICGC	3.158	Loss
CMGC_CDK_CDC2_CDK1_ST	Q09666	AHNAK	P06493	CDK1	S93	H87Q	87	Missense	distal	-6	no	3.165	3.159	EPSD	ICGC	3.158	Down-regulation
CMGC_CDK_CDC2_CDK1_ST	Q09666	AHNAK	P06493	CDK1	S93	R88S	88	Missense	distal	-5	no	3.165	3.108	EPSD	ICGC	3.158	Loss
CMGC_CDK_CDC2_CDK1_ST	Q09666	AHNAK	P06493	CDK1	S93	R92H	92	Missense	proximal	-1	no	3.165	3.189	EPSD	ICGC;COSMIC	3.158	Up-regulation
CMGC_CDK_CDC2_CDK1_ST	Q09666	AHNAK	P06493	CDK1	S93	G90W	90	Missense	distal	-3	no	3.165	3.193	EPSD	ICGC;COSMIC	3.158	Up-regulation
CMGC_CDK_CDC2_CDK1_ST	Q09666	AHNAK	P06493	CDK1	T324	R320C	320	Missense	distal	-4	no	3.806	3.737	EPSD	ICGC	3.158	Down-regulation
CMGC_CDK_CDC2_CDK1_ST	Q09666	AHNAK	P06493	CDK1	T324	A327E	327	Missense	distal	3	no	3.806	3.702	EPSD	ICGC	3.158	Down-regulation
CMGC_CDK_CDC2_CDK1_ST	Q09666	AHNAK	P06493	CDK1	T545	I543T	543	Missense	proximal	-2	no	3.352	3.219	EPSD	ICGC	3.158	Down-regulation
CMGC_CDK_CDC2_CDK1_ST	Q09666	AHNAK	P06493	CDK1	T545	D542E	542	Missense	distal	-3	no	3.352	3.343	EPSD	ICGC	3.158	Down-regulation
CMGC_CDK_CDC2_CDK1_ST	Q09666	AHNAK	P06493	CDK1	T1192	T1192A	1192	Missense	central	0	yes	3.414	0.000	EPSD	ICGC;COSMIC	3.158	Loss
CMGC_CDK_CDC2_CDK1_ST	Q09666	AHNAK	P06493	CDK1	T2832	P2833S	2833	Missense	proximal	1	no	3.419	0.235	EPSD	ICGC	3.158	Loss
CMGC_CDK_CDC2_CDK1_ST	Q09666	AHNAK	P06493	CDK1	T3366	S3360L	3360	Missense	distal	-6	no	3.272	3.300	EPSD	ICGC;COSMIC;CCLE	3.158	Up-regulation
CMGC_CDK_CDC2_CDK1_ST	Q09666	AHNAK	P06493	CDK1	T3716	D3713E	3713	Missense	distal	-3	no	3.654	3.645	EPSD	ICGC	3.158	Down-regulation
CMGC_CDK_CDC2_CDK1_ST	Q09666	AHNAK	P06493	CDK1	T3716	V3712M	3712	Missense	distal	-4	no	3.654	3.695	EPSD	ICGC;COSMIC	3.158	Up-regulation
CMGC_CDK_CDC2_CDK1_ST	Q09666	AHNAK	P06493	CDK1	S4516	M4509L	4509	Missense	distal	-7	no	3.413	3.279	EPSD	ICGC;COSMIC	3.158	Down-regulation
CMGC_CDK_CDC2_CDK1_ST	Q09666	AHNAK	P06493	CDK1	T4766	T4766I	4766	Missense	central	0	yes	3.639	0.000	EPSD	ICGC;COSMIC	3.158	Loss
CMGC_CDK_CDC2_CDK1_ST	Q09666	AHNAK	P06493	CDK1	T4766	D4763E	4763	Missense	distal	-3	no	3.639	3.630	EPSD	ICGC	3.158	Down-regulation
CMGC_CDK_CDC2_CDK1_ST	Q09666	AHNAK	P06493	CDK1	T4766	N4765S	4765	Missense	proximal	-1	no	3.639	3.548	EPSD	ICGC	3.158	Down-regulation
CMGC_CDK_CDC2_CDK1_ST	Q09666	AHNAK	P06493	CDK1	T5184	G5177C	5177	Missense	distal	-7	no	3.571	3.615	EPSD	ICGC;COSMIC	3.158	Up-regulation
CMGC_CDK_CDC2_CDK1_ST	Q09666	AHNAK	P06493	CDK1	S5552	A5551E	5551	Missense	proximal	-1	no	3.359	3.506	EPSD	ICGC	3.158	Up-regulation
CMGC_CDK_CDC2_CDK1_ST	Q09666	AHNAK	P06493	CDK1	S5552	D5556H	5556	Missense	distal	4	no	3.359	3.379	EPSD	ICGC;COSMIC	3.158	Up-regulation
CMGC_CDK_CDC2_CDK1_ST	Q09666	AHNAK	P06493	CDK1	S5731	G5738R	5738	Missense	distal	7	no	3.540	3.521	EPSD	ICGC;COSMIC	3.158	Down-regulation
CMGC_CDK_CDC2_CDK1_ST	Q09666	AHNAK	P06493	CDK1	S5763	A5757T	5757	Missense	distal	-6	no	3.373	3.374	PhosphoSitePlus	ICGC;COSMIC	3.158	Up-regulation
CMGC_CDK_CDC2_CDK1_ST	Q09666	AHNAK	P06493	CDK1	S5763	A5761T	5761	Missense	proximal	-2	no	3.373	3.454	PhosphoSitePlus	ICGC;COSMIC;GDSC;CCLE	3.158	Up-regulation
CMGC_CDK_CDC2_CDK1_ST	Q09666	AHNAK	P06493	CDK1	S5763	A5757E	5757	Missense	distal	-6	no	3.373	3.385	PhosphoSitePlus	ICGC;COSMIC	3.158	Up-regulation
CMGC_CDK_CDC2_CDK1_ST	Q09666	AHNAK	P06493	CDK1	T5794	T5796M	5796	Missense	proximal	2	no	3.321	3.329	EPSD	ICGC;COSMIC;GDSC	3.158	Up-regulation
CMGC_CDK_CDC2_CDK1_ST	Q96IF1	AJUBA	P06493	CDK1	S119	S119G	119	Missense	central	0	yes	3.371	0.000	EPSD;PhosphoSitePlus	ICGC;COSMIC	3.158	Loss
CMGC_CDK_CDC2_CDK1_ST	P55211	CASP9	P06493	CDK1	T125	L121I	121	Missense	distal	-4	no	3.655	3.706	PhosphoSitePlus	ICGC;COSMIC	3.158	Up-regulation
CMGC_CDK_CDC2_CDK1_ST	P55211	CASP9	P06493	CDK1	S302	S302F	302	Missense	central	0	yes	3.188	0.000	EPSD	ICGC	3.158	Loss
CMGC_CDK_CDC2_CDK1_ST	Q13042	CDC16	P06493	CDK1	T589	S595F	595	Missense	distal	6	no	3.383	3.332	EPSD	ICGC;COSMIC	3.158	Down-regulation
CMGC_CDK_CDC2_CDK1_ST	O94782	USP1	P06493	CDK1	S67	R74K	74	Missense	distal	7	no	3.345	3.346	EPSD	ICGC	3.158	Up-regulation
CMGC_CDK_CDC2_CDK1_ST	O94782	USP1	P06493	CDK1	S398	S398C	398	Missense	central	0	yes	3.359	0.000	EPSD	ICGC;COSMIC	3.158	Loss
CMGC_CDK_CDC2_CDK1_ST	O94782	USP1	P06493	CDK1	T404	S398C	398	Missense	distal	-6	no	3.499	3.515	EPSD	ICGC;COSMIC	3.158	Up-regulation
CMGC_CDK_CDC2_CDK1_ST	O94782	USP1	P06493	CDK1	T558	K561T	561	Missense	distal	3	no	3.207	3.119	EPSD	ICGC;COSMIC	3.158	Loss
CMGC_CDK_CDC2_CDK1_ST	O94782	USP1	P06493	CDK1	S768	D762N	762	Missense	distal	-6	no	3.795	3.794	EPSD	ICGC	3.158	Down-regulation
CMGC_CDK_CDC2_CDK1_ST	O94782	USP1	P06493	CDK1	S768	P769S	769	Missense	proximal	1	no	3.795	0.611	EPSD	ICGC	3.158	Loss
CMGC_CDK_CDC2_CDK1_ST	Q92574	TSC1	P06493	CDK1	T357	P359Q	359	Missense	proximal	2	no	3.356	3.357	EPSD	ICGC	3.158	Up-regulation
CMGC_CDK_CDC2_CDK1_ST	Q92574	TSC1	P06493	CDK1	T417	E423V	423	Missense	distal	6	no	3.283	3.267	EPSD;PhosphoSitePlus	ICGC;COSMIC	3.158	Down-regulation
CMGC_CDK_CDC2_CDK1_ST	Q92574	TSC1	P06493	CDK1	T417	T415I	415	Missense	proximal	-2	no	3.283	3.416	EPSD;PhosphoSitePlus	ICGC;COSMIC	3.158	Up-regulation
CMGC_CDK_CDC2_CDK1_ST	Q92574	TSC1	P06493	CDK1	T582	P583H	583	Missense	proximal	1	no	3.782	1.097	EPSD	ICGC;COSMIC	3.158	Loss
CMGC_CDK_CDC2_CDK1_ST	Q92574	TSC1	P06493	CDK1	S584	P583H	583	Missense	proximal	-1	no	3.520	3.554	EPSD;PhosphoSitePlus	ICGC;COSMIC	3.158	Up-regulation
CMGC_CDK_CDC2_CDK1_ST	Q92574	TSC1	P06493	CDK1	S584	P591Q	591	Missense	distal	7	no	3.520	3.521	EPSD;PhosphoSitePlus	ICGC;COSMIC	3.158	Up-regulation
CMGC_CDK_CDC2_CDK1_ST	Q92574	TSC1	P06493	CDK1	S644	V640M	640	Missense	distal	-4	no	3.512	3.553	EPSD	ICGC	3.158	Up-regulation
CMGC_CDK_CDC2_CDK1_ST	Q92574	TSC1	P06493	CDK1	S682	D675N	675	Missense	distal	-7	no	3.246	3.247	EPSD	ICGC;COSMIC	3.158	Up-regulation
CMGC_CDK_CDC2_CDK1_ST	P47736	RAP1GAP	P06493	CDK1	S74	P75S	75	Missense	proximal	1	no	3.462	0.277	EPSD	ICGC;COSMIC	3.158	Loss
CMGC_CDK_CDC2_CDK1_ST	Q92993	KAT5	P06493	CDK1	S90	R87H	87	Missense	distal	-3	no	4.120	4.130	EPSD;PhosphoSitePlus	ICGC;COSMIC	3.158	Up-regulation
CMGC_CDK_CDC2_CDK1_ST	Q92993	KAT5	P06493	CDK1	S90	G89D	89	Missense	proximal	-1	no	4.120	3.985	EPSD;PhosphoSitePlus	ICGC	3.158	Down-regulation
CMGC_CDK_CDC2_CDK1_ST	P56181	NDUFV3	P06493	CDK1	S53	K51N	51	Missense	proximal	-2	no	3.399	3.361	EPSD	ICGC	3.158	Down-regulation
CMGC_CDK_CDC2_CDK1_ST	P56181	NDUFV3	P06493	CDK1	S53	P54S	54	Missense	proximal	1	no	3.399	0.214	EPSD	ICGC	3.158	Loss
CMGC_CDK_CDC2_CDK1_ST	Q01167	FOXK2	P06493	CDK1	S199	S195N	195	Missense	distal	-4	no	3.231	3.159	EPSD	ICGC;COSMIC	3.158	Down-regulation
CMGC_CDK_CDC2_CDK1_ST	Q01167	FOXK2	P06493	CDK1	S199	A206T	206	Missense	distal	7	no	3.231	3.245	EPSD	ICGC	3.158	Up-regulation
CMGC_CDK_CDC2_CDK1_ST	Q01167	FOXK2	P06493	CDK1	S213	A206T	206	Missense	distal	-7	no	3.683	3.676	EPSD	ICGC	3.158	Down-regulation
CMGC_CDK_CDC2_CDK1_ST	Q01167	FOXK2	P06493	CDK1	T648	V641F	641	Missense	distal	-7	no	3.485	3.463	EPSD	ICGC	3.158	Down-regulation
CMGC_CDK_CDC2_CDK1_ST	Q01167	FOXK2	P06493	CDK1	T648	L644M	644	Missense	distal	-4	no	3.485	3.599	EPSD	ICGC;COSMIC	3.158	Up-regulation
CMGC_CDK_CDC2_CDK1_ST	O00418	EEF2K	P06493	CDK1	S74	P75A	75	Missense	proximal	1	no	3.347	2.458	EPSD	ICGC;COSMIC	3.158	Loss
CMGC_CDK_CDC2_CDK1_ST	O00418	EEF2K	P06493	CDK1	S74	P75L	75	Missense	proximal	1	no	3.347	-0.339	EPSD	ICGC;COSMIC	3.158	Loss
CMGC_CDK_CDC2_CDK1_ST	O00418	EEF2K	P06493	CDK1	S74	S71F	71	Missense	distal	-3	no	3.347	3.320	EPSD	ICGC;COSMIC	3.158	Down-regulation
CMGC_CDK_CDC2_CDK1_ST	O00418	EEF2K	P06493	CDK1	S74	F79L	79	Missense	distal	5	no	3.347	3.394	EPSD	ICGC	3.158	Up-regulation
CMGC_CDK_CDC2_CDK1_ST	O00418	EEF2K	P06493	CDK1	S359	Q361R	361	Missense	proximal	2	no	3.244	3.248	PhosphoSitePlus	ICGC	3.158	Up-regulation
CMGC_CDK_CDC2_CDK1_ST	O00418	EEF2K	P06493	CDK1	S359	P360L	360	Missense	proximal	1	no	3.244	-0.442	PhosphoSitePlus	ICGC	3.158	Loss
CMGC_CDK_CDC2_CDK1_ST	O00418	EEF2K	P06493	CDK1	T401	S404C	404	Missense	distal	3	no	3.389	3.340	EPSD	ICGC	3.158	Down-regulation
CMGC_CDK_CDC2_CDK1_ST	Q9BXS6	NUSAP1	P06493	CDK1	S135	Q141K	141	Missense	distal	6	no	3.211	3.203	EPSD	ICGC;COSMIC	3.158	Down-regulation
CMGC_CDK_CDC2_CDK1_ST	Q9BXS6	NUSAP1	P06493	CDK1	T244	R249Q	249	Missense	distal	5	no	3.338	3.362	EPSD	ICGC;COSMIC	3.158	Up-regulation
CMGC_CDK_CDC2_CDK1_ST	Q9BXS6	NUSAP1	P06493	CDK1	T300	A306S	306	Missense	distal	6	no	3.540	3.530	PhosphoSitePlus;EPSD	ICGC	3.158	Down-regulation
CMGC_CDK_CDC2_CDK1_ST	O00443	PIK3C2A	P06493	CDK1	S124	L131I	131	Missense	distal	7	no	3.162	3.158	EPSD	ICGC	3.158	Down-regulation
CMGC_CDK_CDC2_CDK1_ST	P20700	LMNB1	P06493	CDK1	S391	R397H	397	Missense	distal	6	no	3.303	3.284	EPSD	ICGC	3.158	Down-regulation
CMGC_CDK_CDC2_CDK1_ST	P20700	LMNB1	P06493	CDK1	S391	L388F	388	Missense	distal	-3	no	3.303	3.307	EPSD	ICGC	3.158	Up-regulation
CMGC_CDK_CDC2_CDK1_ST	P20700	LMNB1	P06493	CDK1	S391	R397S	397	Missense	distal	6	no	3.303	3.297	EPSD	ICGC;COSMIC	3.158	Down-regulation
CMGC_CDK_CDC2_CDK1_ST	P20700	LMNB1	P06493	CDK1	S393	R397H	397	Missense	distal	4	no	3.361	3.320	EPSD;PhosphoSitePlus	ICGC	3.158	Down-regulation
CMGC_CDK_CDC2_CDK1_ST	P20700	LMNB1	P06493	CDK1	S393	L388F	388	Missense	distal	-5	no	3.361	3.327	EPSD;PhosphoSitePlus	ICGC	3.158	Down-regulation
CMGC_CDK_CDC2_CDK1_ST	P20700	LMNB1	P06493	CDK1	S393	R397S	397	Missense	distal	4	no	3.361	3.343	EPSD;PhosphoSitePlus	ICGC;COSMIC	3.158	Down-regulation
CMGC_CDK_CDC2_CDK1_ST	P20700	LMNB1	P06493	CDK1	T575	L569I	569	Missense	distal	-6	no	3.452	3.446	EPSD	ICGC;COSMIC	3.158	Down-regulation
CMGC_CDK_CDC2_CDK1_ST	P20700	LMNB1	P06493	CDK1	T575	H571N	571	Missense	distal	-4	no	3.452	3.450	EPSD	ICGC;COSMIC	3.158	Down-regulation
CMGC_CDK_CDC2_CDK1_ST	P20700	LMNB1	P06493	CDK1	T575	A578T	578	Missense	distal	3	no	3.452	3.365	EPSD	ICGC;COSMIC	3.158	Down-regulation
CMGC_CDK_CDC2_CDK1_ST	Q01196	RUNX1	P06493	CDK1	S21	M25V	25	Missense	distal	4	no	3.490	3.448	EPSD	ICGC	3.158	Down-regulation
CMGC_CDK_CDC2_CDK1_ST	Q01094	E2F1	P06493	CDK1	S121	S121F	121	Missense	central	0	yes	3.476	0.000	EPSD	ICGC;COSMIC;CCLE	3.158	Loss
CMGC_CDK_CDC2_CDK1_ST	Q01094	E2F1	P06493	CDK1	S121	P122L	122	Missense	proximal	1	no	3.476	-0.210	EPSD	ICGC	3.158	Loss
CMGC_CDK_CDC2_CDK1_ST	Q01094	E2F1	P06493	CDK1	T311	P308T	308	Missense	distal	-3	no	3.452	3.457	EPSD	ICGC	3.158	Up-regulation
CMGC_CDK_CDC2_CDK1_ST	Q01094	E2F1	P06493	CDK1	T311	G305W	305	Missense	distal	-6	no	3.452	3.445	EPSD	ICGC;COSMIC	3.158	Down-regulation
CMGC_CDK_CDC2_CDK1_ST	Q01094	E2F1	P06493	CDK1	T311	S318A	318	Missense	distal	7	no	3.452	3.442	EPSD	ICGC	3.158	Down-regulation
CMGC_CDK_CDC2_CDK1_ST	Q01094	E2F1	P06493	CDK1	T311	G305V	305	Missense	distal	-6	no	3.452	3.449	EPSD	ICGC;COSMIC	3.158	Down-regulation
CMGC_CDK_CDC2_CDK1_ST	Q01094	E2F1	P06493	CDK1	S375	V369M	369	Missense	distal	-6	no	3.327	3.318	EPSD	ICGC	3.158	Down-regulation
CMGC_CDK_CDC2_CDK1_ST	Q01094	E2F1	P06493	CDK1	S403	A408V	408	Missense	distal	5	no	3.534	3.741	EPSD	ICGC;COSMIC	3.158	Up-regulation
CMGC_CDK_CDC2_CDK1_ST	Q01094	E2F1	P06493	CDK1	S403	E397K	397	Missense	distal	-6	no	3.534	3.535	EPSD	ICGC;COSMIC	3.158	Up-regulation
CMGC_CDK_CDC2_CDK1_ST	Q8IWB6	TEX14	P06493	CDK1	S168	D161G	161	Missense	distal	-7	no	3.816	3.718	EPSD	ICGC	3.158	Down-regulation
CMGC_CDK_CDC2_CDK1_ST	Q8IWB6	TEX14	P06493	CDK1	S168	D161N	161	Missense	distal	-7	no	3.816	3.817	EPSD	ICGC;COSMIC	3.158	Up-regulation
CMGC_CDK_CDC2_CDK1_ST	P98170	XIAP	P06493	CDK1	S40	N35D	35	Missense	distal	-5	no	3.582	3.579	PhosphoSitePlus	ICGC;COSMIC	3.158	Down-regulation
CMGC_CDK_CDC2_CDK1_ST	P98170	XIAP	P06493	CDK1	S40	V42F	42	Missense	proximal	2	no	3.582	3.588	PhosphoSitePlus	ICGC	3.158	Up-regulation
CMGC_CDK_CDC2_CDK1_ST	P98170	XIAP	P06493	CDK1	S40	S38C	38	Missense	proximal	-2	no	3.582	3.599	PhosphoSitePlus	ICGC	3.158	Up-regulation
CMGC_CDK_CDC2_CDK1_ST	Q04637	EIF4G1	P06493	CDK1	T205	P208S	208	Missense	distal	3	no	3.267	3.317	EPSD	ICGC;COSMIC	3.158	Up-regulation
CMGC_CDK_CDC2_CDK1_ST	Q04637	EIF4G1	P06493	CDK1	T205	P208H	208	Missense	distal	3	no	3.267	3.296	EPSD	ICGC;GDSC;CCLE	3.158	Up-regulation
CMGC_CDK_CDC2_CDK1_ST	Q04637	EIF4G1	P06493	CDK1	S314	P310L	310	Missense	distal	-4	no	3.471	3.328	EPSD	ICGC;COSMIC	3.158	Down-regulation
CMGC_CDK_CDC2_CDK1_ST	Q04637	EIF4G1	P06493	CDK1	S314	P310H	310	Missense	distal	-4	no	3.471	3.452	EPSD	ICGC;COSMIC	3.158	Down-regulation
CMGC_CDK_CDC2_CDK1_ST	P48200	IREB2	P06493	CDK1	S157	Q151R	151	Missense	distal	-6	no	3.545	3.547	PhosphoSitePlus	ICGC;COSMIC	3.158	Up-regulation
CMGC_CDK_CDC2_CDK1_ST	P48200	IREB2	P06493	CDK1	S157	K155Q	155	Missense	proximal	-2	no	3.545	3.491	PhosphoSitePlus	ICGC	3.158	Down-regulation
CMGC_CDK_CDC2_CDK1_ST	P48200	IREB2	P06493	CDK1	S157	V159L	159	Missense	proximal	2	no	3.545	3.551	PhosphoSitePlus	ICGC	3.158	Up-regulation
CMGC_CDK_CDC2_CDK1_ST	P48200	IREB2	P06493	CDK1	T777	R779L	779	Missense	proximal	2	no	3.293	3.308	EPSD	ICGC	3.158	Up-regulation
CMGC_CDK_CDC2_CDK1_ST	P48200	IREB2	P06493	CDK1	T777	P778L	778	Missense	proximal	1	no	3.293	-0.394	EPSD	ICGC	3.158	Loss
CMGC_CDK_CDC2_CDK1_ST	Q15788	NCOA1	P06493	CDK1	S22	P23S	23	Missense	proximal	1	no	3.582	0.398	EPSD	ICGC;COSMIC	3.158	Loss
CMGC_CDK_CDC2_CDK1_ST	Q15788	NCOA1	P06493	CDK1	S22	A28S	28	Missense	distal	6	no	3.582	3.572	EPSD	ICGC	3.158	Down-regulation
CMGC_CDK_CDC2_CDK1_ST	Q15788	NCOA1	P06493	CDK1	S22	D25Y	25	Missense	distal	3	no	3.582	3.576	EPSD	ICGC	3.158	Down-regulation
CMGC_CDK_CDC2_CDK1_ST	Q15788	NCOA1	P06493	CDK1	S999	L1004F	1004	Missense	distal	5	no	3.621	3.575	EPSD	ICGC;COSMIC	3.158	Down-regulation
CMGC_CDK_CDC2_CDK1_ST	Q15788	NCOA1	P06493	CDK1	S999	S1006I	1006	Missense	distal	7	no	3.621	3.647	EPSD	ICGC	3.158	Up-regulation
CMGC_CDK_CDC2_CDK1_ST	Q15788	NCOA1	P06493	CDK1	S999	A1002S	1002	Missense	distal	3	no	3.621	3.568	EPSD	ICGC	3.158	Down-regulation
CMGC_CDK_CDC2_CDK1_ST	Q15788	NCOA1	P06493	CDK1	S999	P998S	998	Missense	proximal	-1	no	3.621	3.570	EPSD	ICGC	3.158	Down-regulation
CMGC_CDK_CDC2_CDK1_ST	Q15788	NCOA1	P06493	CDK1	S1006	L1004F	1004	Missense	proximal	-2	no	3.320	3.340	EPSD	ICGC;COSMIC	3.158	Up-regulation
CMGC_CDK_CDC2_CDK1_ST	Q15788	NCOA1	P06493	CDK1	S1006	G1010C	1010	Missense	distal	4	no	3.320	3.381	EPSD	ICGC	3.158	Up-regulation
CMGC_CDK_CDC2_CDK1_ST	Q15788	NCOA1	P06493	CDK1	S1006	M1011I	1011	Missense	distal	5	no	3.320	3.415	EPSD	ICGC;COSMIC	3.158	Up-regulation
CMGC_CDK_CDC2_CDK1_ST	Q15788	NCOA1	P06493	CDK1	S1006	S1006I	1006	Missense	central	0	yes	3.320	0.000	EPSD	ICGC	3.158	Loss
CMGC_CDK_CDC2_CDK1_ST	Q15788	NCOA1	P06493	CDK1	S1006	V1012F	1012	Missense	distal	6	no	3.320	3.306	EPSD	ICGC;COSMIC	3.158	Down-regulation
CMGC_CDK_CDC2_CDK1_ST	Q15788	NCOA1	P06493	CDK1	S1006	A1002S	1002	Missense	distal	-4	no	3.320	3.347	EPSD	ICGC	3.158	Up-regulation
CMGC_CDK_CDC2_CDK1_ST	Q15788	NCOA1	P06493	CDK1	S1006	G1010V	1010	Missense	distal	4	no	3.320	3.352	EPSD	ICGC	3.158	Up-regulation
CMGC_CDK_CDC2_CDK1_ST	Q15788	NCOA1	P06493	CDK1	S1006	P1007S	1007	Missense	proximal	1	no	3.320	0.135	EPSD	ICGC	3.158	Loss
CMGC_CDK_CDC2_CDK1_ST	Q08050	FOXM1	P06493	CDK1	T510	P509T	509	Missense	proximal	-1	no	3.316	3.238	EPSD	ICGC;COSMIC	3.158	Down-regulation
CMGC_CDK_CDC2_CDK1_ST	O94762	RECQL5	P06493	CDK1	S727	A732E	732	Missense	distal	5	no	3.147	3.285	PhosphoSitePlus	ICGC;COSMIC	3.158	Gain
CMGC_CDK_CDC2_CDK1_ST	O94762	RECQL5	P06493	CDK1	S954	H947N	947	Missense	distal	-7	no	3.919	3.921	EPSD	ICGC	3.158	Up-regulation
CMGC_CDK_CDC2_CDK1_ST	O94762	RECQL5	P06493	CDK1	S954	Q951R	951	Missense	distal	-3	no	3.919	3.896	EPSD	ICGC;COSMIC	3.158	Down-regulation
CMGC_CDK_CDC2_CDK1_ST	P18754	RCC1	P06493	CDK1	T274	H270R	270	Missense	distal	-4	no	3.303	3.307	PhosphoSitePlus;EPSD	ICGC;COSMIC	3.158	Up-regulation
CMGC_CDK_CDC2_CDK1_ST	P18754	RCC1	P06493	CDK1	T274	Q271H	271	Missense	distal	-3	no	3.303	3.291	PhosphoSitePlus;EPSD	ICGC;COSMIC	3.158	Down-regulation
CMGC_CDK_CDC2_CDK1_ST	Q14807	KIF22	P06493	CDK1	S140	G145V	145	Missense	distal	5	no	4.466	4.433	EPSD	ICGC	3.158	Down-regulation
CMGC_CDK_CDC2_CDK1_ST	Q14807	KIF22	P06493	CDK1	S140	Q143K	143	Missense	distal	3	no	4.466	4.497	EPSD	ICGC;COSMIC	3.158	Up-regulation
CMGC_CDK_CDC2_CDK1_ST	Q14807	KIF22	P06493	CDK1	S412	A417V	417	Missense	distal	5	no	3.048	3.255	EPSD	ICGC	3.158	Gain
CMGC_CDK_CDC2_CDK1_ST	Q14807	KIF22	P06493	CDK1	T463	R466Q	466	Missense	distal	3	no	3.490	3.442	EPSD;PhosphoSitePlus	ICGC;COSMIC	3.158	Down-regulation
CMGC_CDK_CDC2_CDK1_ST	Q14807	KIF22	P06493	CDK1	T463	V470M	470	Missense	distal	7	no	3.490	3.478	EPSD;PhosphoSitePlus	ICGC;COSMIC	3.158	Down-regulation
CMGC_CDK_CDC2_CDK1_ST	Q9Y6Q9	NCOA3	P06493	CDK1	S505	S498F	498	Missense	distal	-7	no	3.211	3.065	EPSD	ICGC;COSMIC	3.158	Loss
CMGC_CDK_CDC2_CDK1_ST	Q9Y6Q9	NCOA3	P06493	CDK1	S543	L548W	548	Missense	distal	5	no	3.666	3.555	EPSD	ICGC;COSMIC	3.158	Down-regulation
CMGC_CDK_CDC2_CDK1_ST	Q9Y6Q9	NCOA3	P06493	CDK1	S551	L548W	548	Missense	distal	-3	no	3.569	3.574	EPSD	ICGC;COSMIC	3.158	Up-regulation
CMGC_CDK_CDC2_CDK1_ST	P02545	LMNA	P06493	CDK1	T19	S22L	22	Missense	distal	3	no	3.189	3.006	PhosphoSitePlus;EPSD	ICGC	3.158	Loss
CMGC_CDK_CDC2_CDK1_ST	P02545	LMNA	P06493	CDK1	T19	G13E	13	Missense	distal	-6	no	3.189	3.176	PhosphoSitePlus;EPSD	ICGC	3.158	Down-regulation
CMGC_CDK_CDC2_CDK1_ST	P02545	LMNA	P06493	CDK1	S22	S22L	22	Missense	central	0	yes	3.172	0.000	EPSD;PhosphoSitePlus	ICGC	3.158	Loss
CMGC_CDK_CDC2_CDK1_ST	P02545	LMNA	P06493	CDK1	S22	T27I	27	Missense	distal	5	no	3.172	3.329	EPSD;PhosphoSitePlus	ICGC;COSMIC	3.158	Up-regulation
CMGC_CDK_CDC2_CDK1_ST	Q9UNH5	CDC14A	P06493	CDK1	S453	A458S	458	Missense	distal	5	no	3.145	3.202	PhosphoSitePlus;EPSD	ICGC	3.158	Gain
CMGC_CDK_CDC2_CDK1_ST	P67870	CSNK2B	P06493	CDK1	S209	S209C	209	Missense	central	0	yes	4.026	0.000	PhosphoSitePlus	ICGC;COSMIC	3.158	Loss
CMGC_CDK_CDC2_CDK1_ST	P55273	CDKN2D	P06493	CDK1	S66	S73F	73	Missense	distal	7	no	3.975	3.997	EPSD	ICGC	3.158	Up-regulation
CMGC_CDK_CDC2_CDK1_ST	P0C1Z6	TFPT	P06493	CDK1	S167	P161Q	161	Missense	distal	-6	no	3.460	3.464	EPSD	ICGC;COSMIC	3.158	Up-regulation
CMGC_CDK_CDC2_CDK1_ST	O43683	BUB1	P06493	CDK1	T3	P4Q	4	Missense	proximal	1	no	3.496	1.073	EPSD	ICGC;COSMIC	3.158	Loss
CMGC_CDK_CDC2_CDK1_ST	O43683	BUB1	P06493	CDK1	T609	A603V	603	Missense	distal	-6	no	3.377	3.398	PhosphoSitePlus;EPSD	ICGC;COSMIC	3.158	Up-regulation
CMGC_CDK_CDC2_CDK1_ST	O43683	BUB1	P06493	CDK1	S655	E659K	659	Missense	distal	4	no	3.213	3.244	EPSD	ICGC;COSMIC	3.158	Up-regulation
CMGC_CDK_CDC2_CDK1_ST	Q14674	ESPL1	P06493	CDK1	S1153	S1149L	1149	Missense	distal	-4	no	3.615	3.421	EPSD	ICGC	3.158	Down-regulation
CMGC_CDK_CDC2_CDK1_ST	Q14674	ESPL1	P06493	CDK1	T1210	N1207Y	1207	Missense	distal	-3	no	3.327	3.311	EPSD	ICGC;COSMIC	3.158	Down-regulation
CMGC_CDK_CDC2_CDK1_ST	Q14674	ESPL1	P06493	CDK1	T1346	G1340S	1340	Missense	distal	-6	no	3.511	3.488	EPSD	ICGC;COSMIC	3.158	Down-regulation
CMGC_CDK_CDC2_CDK1_ST	P54132	BLM	P06493	CDK1	S706	A703V	703	Missense	distal	-3	no	3.363	3.301	EPSD	ICGC;COSMIC	3.158	Down-regulation
CMGC_CDK_CDC2_CDK1_ST	P54132	BLM	P06493	CDK1	S706	V705I	705	Missense	proximal	-1	no	3.363	3.415	EPSD	ICGC	3.158	Up-regulation
CMGC_CDK_CDC2_CDK1_ST	P54132	BLM	P06493	CDK1	S706	V705F	705	Missense	proximal	-1	no	3.363	3.370	EPSD	ICGC;COSMIC	3.158	Up-regulation
CMGC_CDK_CDC2_CDK1_ST	P54132	BLM	P06493	CDK1	S706	C704F	704	Missense	proximal	-2	no	3.363	3.413	EPSD	ICGC	3.158	Up-regulation
CMGC_CDK_CDC2_CDK1_ST	P54132	BLM	P06493	CDK1	S706	T710N	710	Missense	distal	4	no	3.363	3.337	EPSD	ICGC	3.158	Down-regulation
CMGC_CDK_CDC2_CDK1_ST	P54132	BLM	P06493	CDK1	S706	S706Y	706	Missense	central	0	yes	3.363	0.000	EPSD	ICGC	3.158	Loss
CMGC_CDK_CDC2_CDK1_ST	P54132	BLM	P06493	CDK1	S706	P707S	707	Missense	proximal	1	no	3.363	0.178	EPSD	ICGC;COSMIC;GDSC	3.158	Loss
CMGC_CDK_CDC2_CDK1_ST	P54132	BLM	P06493	CDK1	S714	V721L	721	Missense	distal	7	no	3.348	3.354	PhosphoSitePlus;EPSD	ICGC	3.158	Up-regulation
CMGC_CDK_CDC2_CDK1_ST	P54132	BLM	P06493	CDK1	S714	T710N	710	Missense	distal	-4	no	3.348	3.267	PhosphoSitePlus;EPSD	ICGC	3.158	Down-regulation
CMGC_CDK_CDC2_CDK1_ST	P54132	BLM	P06493	CDK1	S714	P707S	707	Missense	distal	-7	no	3.348	3.388	PhosphoSitePlus;EPSD	ICGC;COSMIC;GDSC	3.158	Up-regulation
CMGC_CDK_CDC2_CDK1_ST	P54132	BLM	P06493	CDK1	S1296	P1297Q	1297	Missense	proximal	1	no	3.287	0.864	EPSD	ICGC;COSMIC	3.158	Loss
CMGC_CDK_CDC2_CDK1_ST	P54274	TERF1	P06493	CDK1	T149	R147Q	147	Missense	proximal	-2	no	3.214	3.160	EPSD	ICGC;COSMIC;CCLE	3.158	Down-regulation
CMGC_CDK_CDC2_CDK1_ST	P68400	CSNK2A1	P06493	CDK1	T360	P366H	366	Missense	distal	6	no	3.753	3.748	EPSD;PhosphoSitePlus	ICGC	3.158	Down-regulation
CMGC_CDK_CDC2_CDK1_ST	P68400	CSNK2A1	P06493	CDK1	T360	I355M	355	Missense	distal	-5	no	3.753	3.679	EPSD;PhosphoSitePlus	ICGC	3.158	Down-regulation
CMGC_CDK_CDC2_CDK1_ST	P68400	CSNK2A1	P06493	CDK1	S362	P366H	366	Missense	distal	4	no	3.331	3.304	EPSD;PhosphoSitePlus	ICGC	3.158	Down-regulation
CMGC_CDK_CDC2_CDK1_ST	P68400	CSNK2A1	P06493	CDK1	S362	I355M	355	Missense	distal	-7	no	3.331	3.416	EPSD;PhosphoSitePlus	ICGC	3.158	Up-regulation
CMGC_CDK_CDC2_CDK1_ST	P30305	CDC25B	P06493	CDK1	S15	S12W	12	Missense	distal	-3	no	3.231	3.205	EPSD	ICGC;COSMIC	3.158	Down-regulation
CMGC_CDK_CDC2_CDK1_ST	P30305	CDC25B	P06493	CDK1	S15	P8S	8	Missense	distal	-7	no	3.231	3.271	EPSD	ICGC;COSMIC	3.158	Up-regulation
CMGC_CDK_CDC2_CDK1_ST	P30305	CDC25B	P06493	CDK1	S15	L14V	14	Missense	proximal	-1	no	3.231	3.176	EPSD	ICGC;COSMIC	3.158	Down-regulation
CMGC_CDK_CDC2_CDK1_ST	P30305	CDC25B	P06493	CDK1	S470	E464Q	464	Missense	distal	-6	no	3.246	3.242	EPSD	ICGC;COSMIC	3.158	Down-regulation
CMGC_CDK_CDC2_CDK1_ST	O00571	DDX3X	P06493	CDK1	T323	A322V	322	Missense	proximal	-1	no	3.494	3.694	EPSD;PhosphoSitePlus	ICGC;COSMIC	3.158	Up-regulation
CMGC_CDK_CDC2_CDK1_ST	O00571	DDX3X	P06493	CDK1	T323	M330K	330	Missense	distal	7	no	3.494	3.493	EPSD;PhosphoSitePlus	ICGC;COSMIC	3.158	Down-regulation
CMGC_CDK_CDC2_CDK1_ST	O00571	DDX3X	P06493	CDK1	T323	R326C	326	Missense	distal	3	no	3.494	3.375	EPSD;PhosphoSitePlus	ICGC;COSMIC	3.158	Down-regulation
CMGC_CDK_CDC2_CDK1_ST	O00571	DDX3X	P06493	CDK1	T323	C317F	317	Missense	distal	-6	no	3.494	3.501	EPSD;PhosphoSitePlus	ICGC;COSMIC	3.158	Up-regulation
CMGC_CDK_CDC2_CDK1_ST	O00571	DDX3X	P06493	CDK1	T323	G325R	325	Missense	proximal	2	no	3.494	3.478	EPSD;PhosphoSitePlus	ICGC;COSMIC	3.158	Down-regulation
CMGC_CDK_CDC2_CDK1_ST	O00571	DDX3X	P06493	CDK1	T323	D329Y	329	Missense	distal	6	no	3.494	3.479	EPSD;PhosphoSitePlus	ICGC;COSMIC	3.158	Down-regulation
CMGC_CDK_CDC2_CDK1_ST	O00571	DDX3X	P06493	CDK1	T323	D329V	329	Missense	distal	6	no	3.494	3.480	EPSD;PhosphoSitePlus	ICGC;COSMIC	3.158	Down-regulation
CMGC_CDK_CDC2_CDK1_ST	O00571	DDX3X	P06493	CDK1	S492	F487L	487	Missense	distal	-5	no	3.318	3.352	EPSD	ICGC;COSMIC;GDSC;CCLE	3.158	Up-regulation
CMGC_CDK_CDC2_CDK1_ST	O00571	DDX3X	P06493	CDK1	S492	L495V	495	Missense	distal	3	no	3.318	3.401	EPSD	ICGC;COSMIC	3.158	Up-regulation
CMGC_CDK_CDC2_CDK1_ST	O00571	DDX3X	P06493	CDK1	S492	V496M	496	Missense	distal	4	no	3.318	3.361	EPSD	ICGC;COSMIC	3.158	Up-regulation
CMGC_CDK_CDC2_CDK1_ST	O00571	DDX3X	P06493	CDK1	S492	R488S	488	Missense	distal	-4	no	3.318	3.384	EPSD	ICGC;COSMIC	3.158	Up-regulation
CMGC_CDK_CDC2_CDK1_ST	Q9UGP4	LIMD1	P06493	CDK1	T294	S296P	296	Missense	proximal	2	no	3.302	3.304	EPSD	ICGC;COSMIC	3.158	Up-regulation
CMGC_CDK_CDC2_CDK1_ST	Q9UGP4	LIMD1	P06493	CDK1	T294	A299T	299	Missense	distal	5	no	3.302	3.365	EPSD	ICGC;COSMIC;CCLE	3.158	Up-regulation
CMGC_CDK_CDC2_CDK1_ST	Q9UGP4	LIMD1	P06493	CDK1	S424	R428G	428	Missense	distal	4	no	3.218	3.092	EPSD;PhosphoSitePlus	ICGC	3.158	Loss
CMGC_CDK_CDC2_CDK1_ST	P26368	U2AF2	P06493	CDK1	T135	G141R	141	Missense	distal	6	no	3.547	3.606	EPSD	ICGC;COSMIC;GDSC;CCLE	3.158	Up-regulation
CMGC_CDK_CDC2_CDK1_ST	P26368	U2AF2	P06493	CDK1	T135	V132L	132	Missense	distal	-3	no	3.547	3.534	EPSD	ICGC	3.158	Down-regulation
CMGC_CDK_CDC2_CDK1_ST	P26368	U2AF2	P06493	CDK1	T135	P134Q	134	Missense	proximal	-1	no	3.547	3.546	EPSD	ICGC;COSMIC	3.158	Down-regulation
CMGC_CDK_CDC2_CDK1_ST	P26368	U2AF2	P06493	CDK1	S346	P347H	347	Missense	proximal	1	no	3.817	1.133	EPSD	ICGC;COSMIC	3.158	Loss
CMGC_CDK_CDC2_CDK1_ST	P26368	U2AF2	P06493	CDK1	S346	S346N	346	Missense	central	0	yes	3.817	0.000	EPSD	ICGC;COSMIC	3.158	Loss
CMGC_CDK_CDC2_CDK1_ST	P26368	U2AF2	P06493	CDK1	S346	P348T	348	Missense	proximal	2	no	3.817	3.816	EPSD	ICGC;COSMIC	3.158	Down-regulation
CMGC_CDK_CDC2_CDK1_ST	P10275	AR	P06493	CDK1	T282	A288T	288	Missense	distal	6	no	3.389	3.381	EPSD	ICGC;COSMIC	3.158	Down-regulation
CMGC_CDK_CDC2_CDK1_ST	P10275	AR	P06493	CDK1	T282	R280L	280	Missense	proximal	-2	no	3.389	3.369	EPSD	ICGC	3.158	Down-regulation
CMGC_CDK_CDC2_CDK1_ST	P10275	AR	P06493	CDK1	T282	A288D	288	Missense	distal	6	no	3.389	3.355	EPSD	ICGC;COSMIC	3.158	Down-regulation
CMGC_CDK_CDC2_CDK1_ST	P10275	AR	P06493	CDK1	S310	T317A	317	Missense	distal	7	no	3.685	3.671	PhosphoSitePlus;EPSD	ICGC;COSMIC	3.158	Down-regulation
CMGC_CDK_CDC2_CDK1_ST	P10275	AR	P06493	CDK1	S310	T303S	303	Missense	distal	-7	no	3.685	3.664	PhosphoSitePlus;EPSD	ICGC;COSMIC	3.158	Down-regulation
CMGC_CDK_CDC2_CDK1_ST	P10275	AR	P06493	CDK1	S310	G314R	314	Missense	distal	4	no	3.685	3.811	PhosphoSitePlus;EPSD	ICGC	3.158	Up-regulation
CMGC_CDK_CDC2_CDK1_ST	P10275	AR	P06493	CDK1	S516	Y514H	514	Missense	proximal	-2	no	3.208	3.178	EPSD;PhosphoSitePlus	ICGC;GDSC;CCLE	3.158	Down-regulation
CMGC_CDK_CDC2_CDK1_ST	P10275	AR	P06493	CDK1	S516	S516I	516	Missense	central	0	yes	3.208	0.000	EPSD;PhosphoSitePlus	ICGC	3.158	Loss
CMGC_CDK_CDC2_CDK1_ST	P10275	AR	P06493	CDK1	S516	V509L	509	Missense	distal	-7	no	3.208	3.131	EPSD;PhosphoSitePlus	ICGC;COSMIC	3.158	Loss
CMGC_CDK_CDC2_CDK1_ST	Q14CS0	UBXN2B	P06493	CDK1	S235	I229T	229	Missense	distal	-6	no	3.415	3.391	EPSD	ICGC	3.158	Down-regulation
CMGC_CDK_CDC2_CDK1_ST	Q14CS0	UBXN2B	P06493	CDK1	S235	E238D	238	Missense	distal	3	no	3.415	3.397	EPSD	ICGC;COSMIC	3.158	Down-regulation
CMGC_CDK_CDC2_CDK1_ST	Q14CS0	UBXN2B	P06493	CDK1	S235	E239D	239	Missense	distal	4	no	3.415	3.414	EPSD	ICGC;COSMIC	3.158	Down-regulation
CMGC_CDK_CDC2_CDK1_ST	Q14CS0	UBXN2B	P06493	CDK1	S235	S235F	235	Missense	central	0	yes	3.415	0.000	EPSD	ICGC;COSMIC	3.158	Loss
CMGC_CDK_CDC2_CDK1_ST	Q9BPX3	NCAPG	P06493	CDK1	T332	L337F	337	Missense	distal	5	no	3.510	3.463	EPSD;PhosphoSitePlus	ICGC	3.158	Down-regulation
CMGC_CDK_CDC2_CDK1_ST	Q9BPX3	NCAPG	P06493	CDK1	S844	T840R	840	Missense	distal	-4	no	3.368	3.293	EPSD	ICGC;COSMIC	3.158	Down-regulation
CMGC_CDK_CDC2_CDK1_ST	Q9BPX3	NCAPG	P06493	CDK1	S844	P845Q	845	Missense	proximal	1	no	3.368	0.945	EPSD	ICGC;COSMIC	3.158	Loss
CMGC_CDK_CDC2_CDK1_ST	Q14739	LBR	P06493	CDK1	T200	T196I	196	Missense	distal	-4	no	4.788	4.636	EPSD	ICGC	3.158	Down-regulation
CMGC_CDK_CDC2_CDK1_ST	Q14739	LBR	P06493	CDK1	T200	F197V	197	Missense	distal	-3	no	4.788	4.796	EPSD	ICGC;COSMIC	3.158	Up-regulation
CMGC_CDK_CDC2_CDK1_ST	Q14739	LBR	P06493	CDK1	T200	P201H	201	Missense	proximal	1	no	4.788	2.103	EPSD	ICGC;COSMIC	3.158	Loss
CMGC_CDK_CDC2_CDK1_ST	Q14739	LBR	P06493	CDK1	T284	T284M	284	Missense	central	0	yes	3.490	0.000	EPSD	ICGC;COSMIC	3.158	Loss
CMGC_CDK_CDC2_CDK1_ST	Q14739	LBR	P06493	CDK1	S357	R353Q	353	Missense	distal	-4	no	3.481	3.500	EPSD	ICGC	3.158	Up-regulation
CMGC_CDK_CDC2_CDK1_ST	Q14739	LBR	P06493	CDK1	S357	R353W	353	Missense	distal	-4	no	3.481	3.441	EPSD	ICGC	3.158	Down-regulation
CMGC_CDK_CDC2_CDK1_ST	Q13541	EIF4EBP1	P06493	CDK1	T10	C7S	7	Missense	distal	-3	no	3.739	3.754	EPSD	ICGC;COSMIC	3.158	Up-regulation
CMGC_CDK_CDC2_CDK1_ST	Q13541	EIF4EBP1	P06493	CDK1	T37	G40V	40	Missense	distal	3	no	3.579	3.601	EPSD	ICGC;COSMIC	3.158	Up-regulation
CMGC_CDK_CDC2_CDK1_ST	Q13541	EIF4EBP1	P06493	CDK1	T37	S35I	35	Missense	proximal	-2	no	3.579	3.673	EPSD	ICGC	3.158	Up-regulation
CMGC_CDK_CDC2_CDK1_ST	Q13541	EIF4EBP1	P06493	CDK1	T37	T41S	41	Missense	distal	4	no	3.579	3.571	EPSD	ICGC;COSMIC	3.158	Down-regulation
CMGC_CDK_CDC2_CDK1_ST	Q9NRI5	DISC1	P06493	CDK1	S241	S241C	241	Missense	central	0	yes	3.205	0.000	EPSD	ICGC;COSMIC	3.158	Loss
CMGC_CDK_CDC2_CDK1_ST	Q9NRI5	DISC1	P06493	CDK1	S241	C239F	239	Missense	proximal	-2	no	3.205	3.256	EPSD	ICGC;COSMIC	3.158	Up-regulation
CMGC_CDK_CDC2_CDK1_ST	Q9UNZ2	NSFL1C	P06493	CDK1	S114	P115S	115	Missense	proximal	1	no	3.194	0.009	EPSD	ICGC;COSMIC	3.158	Loss
CMGC_CDK_CDC2_CDK1_ST	Q02750	MAP2K1	P06493	CDK1	S231	P232R	232	Missense	proximal	1	no	3.451	-0.158	EPSD	ICGC	3.158	Loss
CMGC_CDK_CDC2_CDK1_ST	Q02750	MAP2K1	P06493	CDK1	S231	R234I	234	Missense	distal	3	no	3.451	3.283	EPSD	ICGC	3.158	Down-regulation
CMGC_CDK_CDC2_CDK1_ST	Q02750	MAP2K1	P06493	CDK1	S231	G225C	225	Missense	distal	-6	no	3.451	3.445	EPSD	ICGC	3.158	Down-regulation
CMGC_CDK_CDC2_CDK1_ST	Q02750	MAP2K1	P06493	CDK1	T286	P288H	288	Missense	proximal	2	no	3.180	3.190	PhosphoSitePlus;EPSD	ICGC;COSMIC	3.158	Up-regulation
CMGC_CDK_CDC2_CDK1_ST	Q02750	MAP2K1	P06493	CDK1	T292	P288H	288	Missense	distal	-4	no	3.399	3.380	EPSD;PhosphoSitePlus	ICGC;COSMIC	3.158	Down-regulation
CMGC_CDK_CDC2_CDK1_ST	Q02750	MAP2K1	P06493	CDK1	T292	G294W	294	Missense	proximal	2	no	3.399	3.389	EPSD;PhosphoSitePlus	ICGC;COSMIC	3.158	Down-regulation
CMGC_CDK_CDC2_CDK1_ST	Q02750	MAP2K1	P06493	CDK1	T292	P296H	296	Missense	distal	4	no	3.399	3.372	EPSD;PhosphoSitePlus	ICGC;COSMIC	3.158	Down-regulation
CMGC_CDK_CDC2_CDK1_ST	P27816	MAP4	P06493	CDK1	S280	L284S	284	Missense	distal	4	no	3.615	3.734	EPSD	ICGC;COSMIC	3.158	Up-regulation
CMGC_CDK_CDC2_CDK1_ST	P27816	MAP4	P06493	CDK1	S280	T282A	282	Missense	proximal	2	no	3.615	3.608	EPSD	ICGC;COSMIC	3.158	Down-regulation
CMGC_CDK_CDC2_CDK1_ST	P27816	MAP4	P06493	CDK1	S384	I386V	386	Missense	proximal	2	no	3.415	3.411	EPSD	ICGC;COSMIC	3.158	Down-regulation
CMGC_CDK_CDC2_CDK1_ST	P27816	MAP4	P06493	CDK1	S384	K387Q	387	Missense	distal	3	no	3.415	3.384	EPSD	ICGC	3.158	Down-regulation
CMGC_CDK_CDC2_CDK1_ST	P27816	MAP4	P06493	CDK1	S384	E381D	381	Missense	distal	-3	no	3.415	3.425	EPSD	ICGC;COSMIC	3.158	Up-regulation
CMGC_CDK_CDC2_CDK1_ST	P27816	MAP4	P06493	CDK1	T571	V576G	576	Missense	distal	5	no	3.328	3.361	EPSD	ICGC;COSMIC	3.158	Up-regulation
CMGC_CDK_CDC2_CDK1_ST	P27816	MAP4	P06493	CDK1	S624	V628I	628	Missense	distal	4	no	3.543	3.524	EPSD	ICGC;COSMIC	3.158	Down-regulation
CMGC_CDK_CDC2_CDK1_ST	P27816	MAP4	P06493	CDK1	S624	A617S	617	Missense	distal	-7	no	3.543	3.516	EPSD	ICGC	3.158	Down-regulation
CMGC_CDK_CDC2_CDK1_ST	Q8IX90	SKA3	P06493	CDK1	T190	V187I	187	Missense	distal	-3	no	3.325	3.304	EPSD	ICGC;COSMIC	3.158	Down-regulation
CMGC_CDK_CDC2_CDK1_ST	Q8IX90	SKA3	P06493	CDK1	T358	S351Y	351	Missense	distal	-7	no	3.753	3.638	PhosphoSitePlus;EPSD	ICGC	3.158	Down-regulation
CMGC_CDK_CDC2_CDK1_ST	Q8IX90	SKA3	P06493	CDK1	T358	P362Q	362	Missense	distal	4	no	3.753	3.749	PhosphoSitePlus;EPSD	ICGC	3.158	Down-regulation
CMGC_CDK_CDC2_CDK1_ST	Q8IX90	SKA3	P06493	CDK1	T358	T358I	358	Missense	central	0	yes	3.753	0.000	PhosphoSitePlus;EPSD	ICGC;COSMIC	3.158	Loss
CMGC_CDK_CDC2_CDK1_ST	Q8IX90	SKA3	P06493	CDK1	T358	V364I	364	Missense	distal	6	no	3.753	3.741	PhosphoSitePlus;EPSD	ICGC	3.158	Down-regulation
CMGC_CDK_CDC2_CDK1_ST	O60610	DIAPH1	P06493	CDK1	S22	S28L	28	Missense	distal	6	no	3.588	3.524	EPSD	ICGC	3.158	Down-regulation
CMGC_CDK_CDC2_CDK1_ST	O60610	DIAPH1	P06493	CDK1	S22	R15W	15	Missense	distal	-7	no	3.588	3.518	EPSD	ICGC;COSMIC	3.158	Down-regulation
CMGC_CDK_CDC2_CDK1_ST	Q12959	DLG1	P06493	CDK1	T115	P116T	116	Missense	proximal	1	no	3.222	0.788	EPSD	ICGC	3.158	Loss
CMGC_CDK_CDC2_CDK1_ST	Q12959	DLG1	P06493	CDK1	T115	Y110C	110	Missense	distal	-5	no	3.222	3.231	EPSD	ICGC;COSMIC	3.158	Up-regulation
CMGC_CDK_CDC2_CDK1_ST	Q12959	DLG1	P06493	CDK1	T115	R109M	109	Missense	distal	-6	no	3.222	3.225	EPSD	ICGC;COSMIC	3.158	Up-regulation
CMGC_CDK_CDC2_CDK1_ST	Q12959	DLG1	P06493	CDK1	S122	P116T	116	Missense	distal	-6	no	3.534	3.532	EPSD	ICGC	3.158	Down-regulation
CMGC_CDK_CDC2_CDK1_ST	Q12959	DLG1	P06493	CDK1	S158	T163K	163	Missense	distal	5	no	3.415	3.441	EPSD;PhosphoSitePlus	ICGC	3.158	Up-regulation
CMGC_CDK_CDC2_CDK1_ST	P42898	MTHFR	P06493	CDK1	T34	P35Q	35	Missense	proximal	1	no	3.355	0.933	PhosphoSitePlus	ICGC;COSMIC	3.158	Loss
CMGC_CDK_CDC2_CDK1_ST	Q9UPU5	USP24	P06493	CDK1	S1141	S1134F	1134	Missense	distal	-7	no	3.540	3.394	EPSD	ICGC	3.158	Down-regulation
CMGC_CDK_CDC2_CDK1_ST	Q9UPU5	USP24	P06493	CDK1	T1289	Q1283K	1283	Missense	distal	-6	no	3.567	3.573	EPSD	ICGC	3.158	Up-regulation
CMGC_CDK_CDC2_CDK1_ST	Q9UPU5	USP24	P06493	CDK1	T1289	S1294T	1294	Missense	distal	5	no	3.567	3.573	EPSD	ICGC;COSMIC	3.158	Up-regulation
CMGC_CDK_CDC2_CDK1_ST	Q9UPU5	USP24	P06493	CDK1	S1943	S1943Y	1943	Missense	central	0	yes	3.195	0.000	EPSD	ICGC	3.158	Loss
CMGC_CDK_CDC2_CDK1_ST	Q9UPU5	USP24	P06493	CDK1	S2047	P2051T	2051	Missense	distal	4	no	3.218	3.222	EPSD;PhosphoSitePlus	ICGC	3.158	Up-regulation
CMGC_CDK_CDC2_CDK1_ST	Q9UPU5	USP24	P06493	CDK1	S2077	P2082T	2082	Missense	distal	5	no	3.223	3.201	EPSD	ICGC	3.158	Down-regulation
CMGC_CDK_CDC2_CDK1_ST	Q9UPU5	USP24	P06493	CDK1	S2081	P2082T	2082	Missense	proximal	1	no	3.333	0.900	EPSD	ICGC	3.158	Loss
CMGC_CDK_CDC2_CDK1_ST	P24928	POLR2A	P06493	CDK1	T368	S362L	362	Missense	distal	-6	no	3.522	3.550	EPSD	ICGC	3.158	Up-regulation
CMGC_CDK_CDC2_CDK1_ST	P24928	POLR2A	P06493	CDK1	T543	R546C	546	Missense	distal	3	no	3.231	3.111	EPSD	ICGC;COSMIC	3.158	Loss
CMGC_CDK_CDC2_CDK1_ST	P24928	POLR2A	P06493	CDK1	S1948	P1952H	1952	Missense	distal	4	no	3.341	3.314	EPSD	ICGC	3.158	Down-regulation
CMGC_CDK_CDC2_CDK1_ST	P24928	POLR2A	P06493	CDK1	S1962	P1963L	1963	Missense	proximal	1	no	3.683	-0.003	EPSD	ICGC	3.158	Loss
CMGC_CDK_CDC2_CDK1_ST	Q96RL1	UIMC1	P06493	CDK1	S463	E461D	461	Missense	proximal	-2	no	3.281	3.261	EPSD	ICGC;COSMIC	3.158	Down-regulation
CMGC_CDK_CDC2_CDK1_ST	Q96RL1	UIMC1	P06493	CDK1	S463	S463A	463	Missense	central	0	yes	3.281	0.000	EPSD	ICGC	3.158	Loss
CMGC_CDK_CDC2_CDK1_ST	Q9UJX5	ANAPC4	P06493	CDK1	S29	A36S	36	Missense	distal	7	no	3.587	3.598	EPSD	ICGC	3.158	Up-regulation
CMGC_CDK_CDC2_CDK1_ST	Q53EZ4	CEP55	P06493	CDK1	S243	A244P	244	Missense	proximal	1	no	2.600	3.489	EPSD	ICGC;COSMIC	3.158	Gain
CMGC_CDK_CDC2_CDK1_ST	Q53EZ4	CEP55	P06493	CDK1	S428	S428I	428	Missense	central	0	yes	3.623	0.000	EPSD;PhosphoSitePlus	ICGC;COSMIC	3.158	Loss
CMGC_CDK_CDC2_CDK1_ST	Q14C86	GAPVD1	P06493	CDK1	S66	S66F	66	Missense	central	0	yes	3.873	0.000	EPSD	ICGC	3.158	Loss
CMGC_CDK_CDC2_CDK1_ST	Q14C86	GAPVD1	P06493	CDK1	S66	A63V	63	Missense	distal	-3	no	3.873	3.812	EPSD	ICGC;COSMIC	3.158	Down-regulation
CMGC_CDK_CDC2_CDK1_ST	Q14C86	GAPVD1	P06493	CDK1	S66	A63S	63	Missense	distal	-3	no	3.873	3.831	EPSD	ICGC;COSMIC	3.158	Down-regulation
CMGC_CDK_CDC2_CDK1_ST	Q14C86	GAPVD1	P06493	CDK1	S227	R225G	225	Missense	proximal	-2	no	3.723	3.745	EPSD	ICGC	3.158	Up-regulation
CMGC_CDK_CDC2_CDK1_ST	Q14C86	GAPVD1	P06493	CDK1	T390	G385R	385	Missense	distal	-5	no	3.188	3.120	EPSD	ICGC;COSMIC	3.158	Loss
CMGC_CDK_CDC2_CDK1_ST	Q14C86	GAPVD1	P06493	CDK1	T390	R386H	386	Missense	distal	-4	no	3.188	3.184	EPSD	ICGC	3.158	Down-regulation
CMGC_CDK_CDC2_CDK1_ST	Q14C86	GAPVD1	P06493	CDK1	T390	G384W	384	Missense	distal	-6	no	3.188	3.180	EPSD	ICGC	3.158	Down-regulation
CMGC_CDK_CDC2_CDK1_ST	Q14C86	GAPVD1	P06493	CDK1	S801	V799F	799	Missense	proximal	-2	no	3.215	3.237	EPSD	ICGC;COSMIC	3.158	Up-regulation
CMGC_CDK_CDC2_CDK1_ST	Q14C86	GAPVD1	P06493	CDK1	T1389	R1391W	1391	Missense	proximal	2	no	3.666	3.672	EPSD	ICGC;COSMIC	3.158	Up-regulation
CMGC_CDK_CDC2_CDK1_ST	Q14C86	GAPVD1	P06493	CDK1	T1389	R1382S	1382	Missense	distal	-7	no	3.666	3.702	EPSD	ICGC	3.158	Up-regulation
CMGC_CDK_CDC2_CDK1_ST	Q14C86	GAPVD1	P06493	CDK1	T1389	I1384T	1384	Missense	distal	-5	no	3.666	3.534	EPSD	ICGC;COSMIC	3.158	Down-regulation
CMGC_CDK_CDC2_CDK1_ST	P06748	NPM1	P06493	CDK1	S10	M9I	9	Missense	proximal	-1	no	3.465	3.575	EPSD	ICGC	3.158	Up-regulation
CMGC_CDK_CDC2_CDK1_ST	P06748	NPM1	P06493	CDK1	S10	D3H	3	Missense	distal	-7	no	3.465	3.464	EPSD	ICGC;COSMIC	3.158	Down-regulation
CMGC_CDK_CDC2_CDK1_ST	P06748	NPM1	P06493	CDK1	S70	Y67D	67	Missense	distal	-3	no	3.554	3.569	PhosphoSitePlus;EPSD	ICGC;COSMIC	3.158	Up-regulation
CMGC_CDK_CDC2_CDK1_ST	P06748	NPM1	P06493	CDK1	S70	E68K	68	Missense	proximal	-2	no	3.554	3.582	PhosphoSitePlus;EPSD	ICGC;COSMIC	3.158	Up-regulation
CMGC_CDK_CDC2_CDK1_ST	P06748	NPM1	P06493	CDK1	S70	M65L	65	Missense	distal	-5	no	3.554	3.642	PhosphoSitePlus;EPSD	ICGC;GDSC;CCLE	3.158	Up-regulation
CMGC_CDK_CDC2_CDK1_ST	P06748	NPM1	P06493	CDK1	T95	V99F	99	Missense	distal	4	no	3.457	3.436	EPSD	ICGC	3.158	Down-regulation
CMGC_CDK_CDC2_CDK1_ST	P06748	NPM1	P06493	CDK1	T95	V99L	99	Missense	distal	4	no	3.457	3.413	EPSD	ICGC;COSMIC	3.158	Down-regulation
CMGC_CDK_CDC2_CDK1_ST	P06748	NPM1	P06493	CDK1	T95	L102F	102	Missense	distal	7	no	3.457	3.449	EPSD	ICGC;COSMIC	3.158	Down-regulation
CMGC_CDK_CDC2_CDK1_ST	P06748	NPM1	P06493	CDK1	T95	G90R	90	Missense	distal	-5	no	3.457	3.388	EPSD	ICGC;COSMIC	3.158	Down-regulation
CMGC_CDK_CDC2_CDK1_ST	P06748	NPM1	P06493	CDK1	T95	S88F	88	Missense	distal	-7	no	3.457	3.310	EPSD	ICGC;COSMIC	3.158	Down-regulation
CMGC_CDK_CDC2_CDK1_ST	P06748	NPM1	P06493	CDK1	T95	V99A	99	Missense	distal	4	no	3.457	3.592	EPSD	ICGC;COSMIC	3.158	Up-regulation
CMGC_CDK_CDC2_CDK1_ST	Q9Y2I6	NINL	P06493	CDK1	S185	S185G	185	Missense	central	0	yes	3.334	0.000	EPSD;PhosphoSitePlus	ICGC;COSMIC	3.158	Loss
CMGC_CDK_CDC2_CDK1_ST	Q9Y2I6	NINL	P06493	CDK1	S585	W588R	588	Missense	distal	3	no	3.094	3.223	EPSD	ICGC	3.158	Gain
CMGC_CDK_CDC2_CDK1_ST	Q9Y2I6	NINL	P06493	CDK1	S589	H584Y	584	Missense	distal	-5	no	3.199	3.227	PhosphoSitePlus;EPSD	ICGC	3.158	Up-regulation
CMGC_CDK_CDC2_CDK1_ST	Q9Y2I6	NINL	P06493	CDK1	S589	W588R	588	Missense	proximal	-1	no	3.199	3.127	PhosphoSitePlus;EPSD	ICGC	3.158	Loss
CMGC_CDK_CDC2_CDK1_ST	Q9Y2I6	NINL	P06493	CDK1	S589	R593S	593	Missense	distal	4	no	3.199	3.181	PhosphoSitePlus;EPSD	ICGC	3.158	Down-regulation
CMGC_CDK_CDC2_CDK1_ST	Q9Y2I6	NINL	P06493	CDK1	S589	P586L	586	Missense	distal	-3	no	3.199	3.167	PhosphoSitePlus;EPSD	ICGC	3.158	Down-regulation
CMGC_CDK_CDC2_CDK1_ST	Q9Y2I6	NINL	P06493	CDK1	S589	R583Q	583	Missense	distal	-6	no	3.199	3.197	PhosphoSitePlus;EPSD	ICGC;COSMIC	3.158	Down-regulation
CMGC_CDK_CDC2_CDK1_ST	Q9Y2I6	NINL	P06493	CDK1	S589	S585C	585	Missense	distal	-4	no	3.199	3.063	PhosphoSitePlus;EPSD	ICGC;COSMIC	3.158	Loss
CMGC_CDK_CDC2_CDK1_ST	Q8NHV4	NEDD1	P06493	CDK1	S215	A209G	209	Missense	distal	-6	no	3.314	3.339	EPSD	ICGC	3.158	Up-regulation
CMGC_CDK_CDC2_CDK1_ST	Q8NHV4	NEDD1	P06493	CDK1	S215	L220F	220	Missense	distal	5	no	3.314	3.268	EPSD	ICGC	3.158	Down-regulation
CMGC_CDK_CDC2_CDK1_ST	Q8NHV4	NEDD1	P06493	CDK1	S215	P216T	216	Missense	proximal	1	no	3.314	0.881	EPSD	ICGC;COSMIC	3.158	Loss
CMGC_CDK_CDC2_CDK1_ST	Q8NHV4	NEDD1	P06493	CDK1	S282	D276Y	276	Missense	distal	-6	no	3.636	3.643	EPSD	ICGC	3.158	Up-regulation
CMGC_CDK_CDC2_CDK1_ST	Q8NHV4	NEDD1	P06493	CDK1	S411	S404G	404	Missense	distal	-7	no	3.989	3.831	EPSD;PhosphoSitePlus	ICGC;COSMIC	3.158	Down-regulation
CMGC_CDK_CDC2_CDK1_ST	Q8NHV4	NEDD1	P06493	CDK1	S411	M409I	409	Missense	proximal	-2	no	3.989	4.065	EPSD;PhosphoSitePlus	ICGC	3.158	Up-regulation
CMGC_CDK_CDC2_CDK1_ST	Q8NHV4	NEDD1	P06493	CDK1	S411	G407C	407	Missense	distal	-4	no	3.989	3.991	EPSD;PhosphoSitePlus	ICGC;COSMIC	3.158	Up-regulation
CMGC_CDK_CDC2_CDK1_ST	Q8NHV4	NEDD1	P06493	CDK1	S411	F410L	410	Missense	proximal	-1	no	3.989	4.038	EPSD;PhosphoSitePlus	ICGC;COSMIC	3.158	Up-regulation
CMGC_CDK_CDC2_CDK1_ST	Q8NHV4	NEDD1	P06493	CDK1	S411	P412H	412	Missense	proximal	1	no	3.989	1.305	EPSD;PhosphoSitePlus	ICGC;COSMIC	3.158	Loss
CMGC_CDK_CDC2_CDK1_ST	Q8NHV4	NEDD1	P06493	CDK1	S411	V418A	418	Missense	distal	7	no	3.989	3.955	EPSD;PhosphoSitePlus	ICGC;COSMIC	3.158	Down-regulation
CMGC_CDK_CDC2_CDK1_ST	Q8NHV4	NEDD1	P06493	CDK1	T550	P553Q	553	Missense	distal	3	no	3.105	3.177	EPSD;PhosphoSitePlus	ICGC;COSMIC	3.158	Gain
CMGC_CDK_CDC2_CDK1_ST	Q9BTA9	WAC	P06493	CDK1	S64	S64I	64	Missense	central	0	yes	3.405	0.000	EPSD	ICGC	3.158	Loss
CMGC_CDK_CDC2_CDK1_ST	Q14157	UBAP2L	P06493	CDK1	S477	Q483H	483	Missense	distal	6	no	3.457	3.455	EPSD	ICGC;COSMIC	3.158	Down-regulation
CMGC_CDK_CDC2_CDK1_ST	O75154	RAB11FIP3	P06493	CDK1	S102	A101V	101	Missense	proximal	-1	no	2.966	3.166	PhosphoSitePlus	ICGC;COSMIC	3.158	Gain
CMGC_CDK_CDC2_CDK1_ST	Q8NCD3	HJURP	P06493	CDK1	T178	R173G	173	Missense	distal	-5	no	3.099	3.167	EPSD	ICGC	3.158	Gain
CMGC_CDK_CDC2_CDK1_ST	P46013	MKI67	P06493	CDK1	S235	W238R	238	Missense	distal	3	no	3.607	3.736	EPSD	ICGC;COSMIC	3.158	Up-regulation
CMGC_CDK_CDC2_CDK1_ST	P46013	MKI67	P06493	CDK1	T328	V323M	323	Missense	distal	-5	no	3.342	3.281	EPSD	ICGC;GDSC	3.158	Down-regulation
CMGC_CDK_CDC2_CDK1_ST	P46013	MKI67	P06493	CDK1	T328	R321K	321	Missense	distal	-7	no	3.342	3.266	EPSD	ICGC;COSMIC	3.158	Down-regulation
CMGC_CDK_CDC2_CDK1_ST	P46013	MKI67	P06493	CDK1	T347	P342Q	342	Missense	distal	-5	no	3.547	3.550	EPSD	ICGC;COSMIC	3.158	Up-regulation
CMGC_CDK_CDC2_CDK1_ST	P46013	MKI67	P06493	CDK1	T347	Q353R	353	Missense	distal	6	no	3.547	3.565	EPSD	ICGC	3.158	Up-regulation
CMGC_CDK_CDC2_CDK1_ST	P46013	MKI67	P06493	CDK1	S1071	K1069E	1069	Missense	proximal	-2	no	3.302	3.273	EPSD	ICGC;COSMIC	3.158	Down-regulation
CMGC_CDK_CDC2_CDK1_ST	P46013	MKI67	P06493	CDK1	T1923	L1930F	1930	Missense	distal	7	no	3.161	3.154	EPSD	ICGC;COSMIC	3.158	Loss
CMGC_CDK_CDC2_CDK1_ST	P46013	MKI67	P06493	CDK1	T2352	T2356N	2356	Missense	distal	4	no	3.281	3.255	EPSD	ICGC;COSMIC	3.158	Down-regulation
CMGC_CDK_CDC2_CDK1_ST	P46013	MKI67	P06493	CDK1	S2528	D2534Y	2534	Missense	distal	6	no	3.238	3.223	EPSD	ICGC;COSMIC	3.158	Down-regulation
CMGC_CDK_CDC2_CDK1_ST	O94901	SUN1	P06493	CDK1	S48	R53H	53	Missense	distal	5	no	3.410	3.475	EPSD;PhosphoSitePlus	ICGC;COSMIC;GDSC;CCLE	3.158	Up-regulation
CMGC_CDK_CDC2_CDK1_ST	O94901	SUN1	P06493	CDK1	S48	R54H	54	Missense	distal	6	no	3.410	3.391	EPSD;PhosphoSitePlus	ICGC	3.158	Down-regulation
CMGC_CDK_CDC2_CDK1_ST	O94901	SUN1	P06493	CDK1	S48	R50L	50	Missense	proximal	2	no	3.410	3.425	EPSD;PhosphoSitePlus	ICGC;COSMIC	3.158	Up-regulation
CMGC_CDK_CDC2_CDK1_ST	O94901	SUN1	P06493	CDK1	S728	S728L	728	Missense	central	0	yes	3.522	0.000	EPSD	ICGC	3.158	Loss
CMGC_CDK_CDC2_CDK1_ST	Q9UQR0	SCML2	P06493	CDK1	S499	R498Q	498	Missense	proximal	-1	no	3.333	3.322	EPSD	ICGC;COSMIC	3.158	Down-regulation
CMGC_CDK_CDC2_CDK1_ST	Q9UQR0	SCML2	P06493	CDK1	S590	L585I	585	Missense	distal	-5	no	3.218	3.204	EPSD;PhosphoSitePlus	ICGC;COSMIC	3.158	Down-regulation
CMGC_CDK_CDC2_CDK1_ST	Q9UQR0	SCML2	P06493	CDK1	S590	P595T	595	Missense	distal	5	no	3.218	3.196	EPSD;PhosphoSitePlus	ICGC;COSMIC	3.158	Down-regulation
CMGC_CDK_CDC2_CDK1_ST	Q9UQR0	SCML2	P06493	CDK1	S590	G587W	587	Missense	distal	-3	no	3.218	3.245	EPSD;PhosphoSitePlus	ICGC;COSMIC	3.158	Up-regulation
CMGC_CDK_CDC2_CDK1_ST	Q9UQR0	SCML2	P06493	CDK1	S590	G587V	587	Missense	distal	-3	no	3.218	3.253	EPSD;PhosphoSitePlus	ICGC;COSMIC	3.158	Up-regulation
CMGC_CDK_CDC2_CDK1_ST	Q9UQR0	SCML2	P06493	CDK1	S590	D588Y	588	Missense	proximal	-2	no	3.218	3.250	EPSD;PhosphoSitePlus	ICGC	3.158	Up-regulation
CMGC_CDK_CDC2_CDK1_ST	P00533	EGFR	P06493	CDK1	T693	A698T	698	Missense	distal	5	no	3.602	3.665	EPSD	ICGC;COSMIC	3.158	Up-regulation
CMGC_CDK_CDC2_CDK1_ST	Q99708	RBBP8	P06493	CDK1	S10	S10I	10	Missense	central	0	yes	3.676	0.000	EPSD	ICGC;COSMIC	3.158	Loss
CMGC_CDK_CDC2_CDK1_ST	Q99708	RBBP8	P06493	CDK1	S10	A14S	14	Missense	distal	4	no	3.676	3.616	EPSD	ICGC	3.158	Down-regulation
CMGC_CDK_CDC2_CDK1_ST	Q99708	RBBP8	P06493	CDK1	S10	S6N	6	Missense	distal	-4	no	3.676	3.603	EPSD	ICGC;COSMIC	3.158	Down-regulation
CMGC_CDK_CDC2_CDK1_ST	Q99708	RBBP8	P06493	CDK1	S163	P164L	164	Missense	proximal	1	no	3.404	-0.282	EPSD	ICGC;COSMIC	3.158	Loss
CMGC_CDK_CDC2_CDK1_ST	Q99708	RBBP8	P06493	CDK1	S163	A167S	167	Missense	distal	4	no	3.404	3.344	EPSD	ICGC;COSMIC	3.158	Down-regulation
CMGC_CDK_CDC2_CDK1_ST	Q99708	RBBP8	P06493	CDK1	S163	P161S	161	Missense	proximal	-2	no	3.404	3.530	EPSD	ICGC	3.158	Up-regulation
CMGC_CDK_CDC2_CDK1_ST	Q99708	RBBP8	P06493	CDK1	S163	P164Q	164	Missense	proximal	1	no	3.404	0.981	EPSD	ICGC;COSMIC	3.158	Loss
CMGC_CDK_CDC2_CDK1_ST	Q99708	RBBP8	P06493	CDK1	S163	V159I	159	Missense	distal	-4	no	3.404	3.382	EPSD	ICGC;COSMIC	3.158	Down-regulation
CMGC_CDK_CDC2_CDK1_ST	Q99708	RBBP8	P06493	CDK1	T245	S243I	243	Missense	proximal	-2	no	3.549	3.643	EPSD	ICGC;COSMIC	3.158	Up-regulation
CMGC_CDK_CDC2_CDK1_ST	Q99708	RBBP8	P06493	CDK1	S889	S889C	889	Missense	central	0	yes	3.699	0.000	EPSD	ICGC;COSMIC	3.158	Loss
CMGC_CDK_CDC2_CDK1_ST	Q99708	RBBP8	P06493	CDK1	S889	I887V	887	Missense	proximal	-2	no	3.699	3.651	EPSD	ICGC;COSMIC	3.158	Down-regulation
CMGC_CDK_CDC2_CDK1_ST	Q99708	RBBP8	P06493	CDK1	S889	Q882H	882	Missense	distal	-7	no	3.699	3.667	EPSD	ICGC	3.158	Down-regulation
CMGC_CDK_CDC2_CDK1_ST	Q99708	RBBP8	P06493	CDK1	S889	G892C	892	Missense	distal	3	no	3.699	3.773	EPSD	ICGC;COSMIC	3.158	Up-regulation
CMGC_CDK_CDC2_CDK1_ST	Q99708	RBBP8	P06493	CDK1	S889	S889Y	889	Missense	central	0	yes	3.699	0.000	EPSD	ICGC;COSMIC	3.158	Loss
CMGC_CDK_CDC2_CDK1_ST	O00562	PITPNM1	P06493	CDK1	S382	S382F	382	Missense	central	0	yes	3.280	0.000	EPSD;PhosphoSitePlus	ICGC;COSMIC	3.158	Loss
CMGC_CDK_CDC2_CDK1_ST	O00562	PITPNM1	P06493	CDK1	S382	E385D	385	Missense	distal	3	no	3.280	3.262	EPSD;PhosphoSitePlus	ICGC;COSMIC	3.158	Down-regulation
CMGC_CDK_CDC2_CDK1_ST	O00562	PITPNM1	P06493	CDK1	T389	S382F	382	Missense	distal	-7	no	3.279	3.132	EPSD	ICGC;COSMIC	3.158	Loss
CMGC_CDK_CDC2_CDK1_ST	O00562	PITPNM1	P06493	CDK1	T389	A396E	396	Missense	distal	7	no	3.279	3.303	EPSD	ICGC	3.158	Up-regulation
CMGC_CDK_CDC2_CDK1_ST	O00562	PITPNM1	P06493	CDK1	T389	G393A	393	Missense	distal	4	no	3.279	3.446	EPSD	ICGC;COSMIC	3.158	Up-regulation
CMGC_CDK_CDC2_CDK1_ST	O00562	PITPNM1	P06493	CDK1	T389	P392L	392	Missense	distal	3	no	3.279	3.146	EPSD	ICGC	3.158	Loss
CMGC_CDK_CDC2_CDK1_ST	O00562	PITPNM1	P06493	CDK1	T389	E385D	385	Missense	distal	-4	no	3.279	3.280	EPSD	ICGC;COSMIC	3.158	Up-regulation
CMGC_CDK_CDC2_CDK1_ST	Q9Y2V2	CARHSP1	P06493	CDK1	T23	G19W	19	Missense	distal	-4	no	3.319	3.350	PhosphoSitePlus	ICGC;COSMIC	3.158	Up-regulation
CMGC_CDK_CDC2_CDK1_ST	Q9Y2V2	CARHSP1	P06493	CDK1	T80	F78V	78	Missense	proximal	-2	no	3.594	3.572	EPSD	ICGC;COSMIC	3.158	Down-regulation
CMGC_CDK_CDC2_CDK1_ST	O00429	DNM1L	P06493	CDK1	S126	K123N	123	Missense	distal	-3	no	3.395	3.415	EPSD	ICGC;COSMIC	3.158	Up-regulation
CMGC_CDK_CDC2_CDK1_ST	O00429	DNM1L	P06493	CDK1	S548	A553T	553	Missense	distal	5	no	3.121	3.185	EPSD	ICGC	3.158	Gain
CMGC_CDK_CDC2_CDK1_ST	O00429	DNM1L	P06493	CDK1	S548	A553V	553	Missense	distal	5	no	3.121	3.329	EPSD	ICGC;COSMIC	3.158	Gain
CMGC_CDK_CDC2_CDK1_ST	O00512	BCL9	P06493	CDK1	S62	A56T	56	Missense	distal	-6	no	3.412	3.413	EPSD	ICGC;COSMIC	3.158	Up-regulation
CMGC_CDK_CDC2_CDK1_ST	O00512	BCL9	P06493	CDK1	T172	A174S	174	Missense	proximal	2	no	3.232	3.238	PhosphoSitePlus	ICGC	3.158	Up-regulation
CMGC_CDK_CDC2_CDK1_ST	O00512	BCL9	P06493	CDK1	S441	P448H	448	Missense	distal	7	no	3.178	3.185	EPSD	ICGC	3.158	Up-regulation
CMGC_CDK_CDC2_CDK1_ST	O00512	BCL9	P06493	CDK1	S687	R690S	690	Missense	distal	3	no	3.240	3.169	EPSD	ICGC;COSMIC	3.158	Down-regulation
CMGC_CDK_CDC2_CDK1_ST	O00512	BCL9	P06493	CDK1	S930	L926P	926	Missense	distal	-4	no	3.047	3.191	EPSD	ICGC	3.158	Gain
CMGC_CDK_CDC2_CDK1_ST	O00512	BCL9	P06493	CDK1	S930	P929L	929	Missense	proximal	-1	no	3.047	3.198	EPSD	ICGC;COSMIC	3.158	Gain
CMGC_CDK_CDC2_CDK1_ST	O00512	BCL9	P06493	CDK1	S930	S935F	935	Missense	distal	5	no	3.047	3.214	EPSD	ICGC;COSMIC	3.158	Gain
CMGC_CDK_CDC2_CDK1_ST	O00311	CDC7	P06493	CDK1	S16	E11D	11	Missense	distal	-5	no	3.390	3.380	EPSD	ICGC	3.158	Down-regulation
CMGC_CDK_CDC2_CDK1_ST	O00311	CDC7	P06493	CDK1	S16	P12S	12	Missense	distal	-4	no	3.390	3.440	EPSD	ICGC;COSMIC	3.158	Up-regulation
CMGC_CDK_CDC2_CDK1_ST	P29692	EEF1D	P06493	CDK1	S133	V132I	132	Missense	proximal	-1	no	3.494	3.547	PhosphoSitePlus	ICGC	3.158	Up-regulation
CMGC_CDK_CDC2_CDK1_ST	P29692	EEF1D	P06493	CDK1	S133	M135I	135	Missense	proximal	2	no	3.494	3.507	PhosphoSitePlus	ICGC;COSMIC	3.158	Up-regulation
CMGC_CDK_CDC2_CDK1_ST	O14773	TPP1	P06493	CDK1	T478	S475L	475	Missense	distal	-3	no	3.315	3.284	EPSD	ICGC	3.158	Down-regulation
CMGC_CDK_CDC2_CDK1_ST	P31350	RRM2	P06493	CDK1	S20	Q15R	15	Missense	distal	-5	no	3.329	3.361	EPSD;PhosphoSitePlus	ICGC;COSMIC	3.158	Up-regulation
CMGC_CDK_CDC2_CDK1_ST	P31350	RRM2	P06493	CDK1	T33	G39W	39	Missense	distal	6	no	3.423	3.444	PhosphoSitePlus;EPSD	ICGC;COSMIC	3.158	Up-regulation
CMGC_CDK_CDC2_CDK1_ST	P16949	STMN1	P06493	CDK1	S25	L24F	24	Missense	proximal	-1	no	3.749	3.700	PhosphoSitePlus;EPSD	ICGC;COSMIC	3.158	Down-regulation
CMGC_CDK_CDC2_CDK1_ST	P16949	STMN1	P06493	CDK1	S25	E30K	30	Missense	distal	5	no	3.749	3.701	PhosphoSitePlus;EPSD	ICGC	3.158	Down-regulation
CMGC_CDK_CDC2_CDK1_ST	P16949	STMN1	P06493	CDK1	S25	E30Q	30	Missense	distal	5	no	3.749	3.683	PhosphoSitePlus;EPSD	ICGC;COSMIC	3.158	Down-regulation
CMGC_CDK_CDC2_CDK1_ST	P16949	STMN1	P06493	CDK1	S25	S31P	31	Missense	distal	6	no	3.749	3.741	PhosphoSitePlus;EPSD	ICGC;COSMIC	3.158	Down-regulation
CMGC_CDK_CDC2_CDK1_ST	P16949	STMN1	P06493	CDK1	S38	S31P	31	Missense	distal	-7	no	3.443	3.403	EPSD;PhosphoSitePlus	ICGC;COSMIC	3.158	Down-regulation
CMGC_CDK_CDC2_CDK1_ST	O75306	NDUFS2	P06493	CDK1	S364	A361D	361	Missense	distal	-3	no	3.587	3.528	PhosphoSitePlus	ICGC;COSMIC	3.158	Down-regulation
CMGC_CDK_CDC2_CDK1_ST	P11387	TOP1	P06493	CDK1	S394	G398E	398	Missense	distal	4	no	3.284	3.347	PhosphoSitePlus;EPSD	ICGC;COSMIC	3.158	Up-regulation
CMGC_CDK_CDC2_CDK1_ST	P11387	TOP1	P06493	CDK1	S394	A390S	390	Missense	distal	-4	no	3.284	3.311	PhosphoSitePlus;EPSD	ICGC	3.158	Up-regulation
CMGC_CDK_CDC2_CDK1_ST	P78344	EIF4G2	P06493	CDK1	T89	D94Y	94	Missense	distal	5	no	3.991	4.021	EPSD	ICGC;COSMIC	3.158	Up-regulation
CMGC_CDK_CDC2_CDK1_ST	P78344	EIF4G2	P06493	CDK1	T89	G83S	83	Missense	distal	-6	no	3.991	3.968	EPSD	ICGC	3.158	Down-regulation
CMGC_CDK_CDC2_CDK1_ST	P06400	RB1	P06493	CDK1	T356	Q354H	354	Missense	proximal	-2	no	3.378	3.386	EPSD	ICGC;COSMIC	3.158	Up-regulation
CMGC_CDK_CDC2_CDK1_ST	P06400	RB1	P06493	CDK1	S780	P783L	783	Missense	distal	3	no	3.910	3.777	EPSD	ICGC	3.158	Down-regulation
CMGC_CDK_CDC2_CDK1_ST	P06400	RB1	P06493	CDK1	S807	G801E	801	Missense	distal	-6	no	3.756	3.743	EPSD;PhosphoSitePlus	ICGC	3.158	Down-regulation
CMGC_CDK_CDC2_CDK1_ST	Q69YH5	CDCA2	P06493	CDK1	S98	G94S	94	Missense	distal	-4	no	3.244	3.382	EPSD	ICGC	3.158	Up-regulation
CMGC_CDK_CDC2_CDK1_ST	Q69YH5	CDCA2	P06493	CDK1	S98	E100K	100	Missense	proximal	2	no	3.244	3.239	EPSD	ICGC	3.158	Down-regulation
CMGC_CDK_CDC2_CDK1_ST	Q69YH5	CDCA2	P06493	CDK1	S120	D125H	125	Missense	distal	5	no	3.204	3.171	EPSD	ICGC;COSMIC	3.158	Down-regulation
CMGC_CDK_CDC2_CDK1_ST	Q69YH5	CDCA2	P06493	CDK1	T321	R328H	328	Missense	distal	7	no	3.165	3.166	EPSD	ICGC;COSMIC	3.158	Up-regulation
CMGC_CDK_CDC2_CDK1_ST	Q69YH5	CDCA2	P06493	CDK1	T321	P322H	322	Missense	proximal	1	no	3.165	0.481	EPSD	ICGC	3.158	Loss
CMGC_CDK_CDC2_CDK1_ST	Q69YH5	CDCA2	P06493	CDK1	T412	P413L	413	Missense	proximal	1	no	3.839	0.153	PhosphoSitePlus	ICGC	3.158	Loss
CMGC_CDK_CDC2_CDK1_ST	Q69YH5	CDCA2	P06493	CDK1	T412	A410G	410	Missense	proximal	-2	no	3.839	4.048	PhosphoSitePlus	ICGC	3.158	Up-regulation
CMGC_CDK_CDC2_CDK1_ST	Q69YH5	CDCA2	P06493	CDK1	S437	E441Q	441	Missense	distal	4	no	3.507	3.551	EPSD	ICGC;COSMIC	3.158	Up-regulation
CMGC_CDK_CDC2_CDK1_ST	Q69YH5	CDCA2	P06493	CDK1	S437	E435Q	435	Missense	proximal	-2	no	3.507	3.482	EPSD	ICGC;COSMIC	3.158	Down-regulation
CMGC_CDK_CDC2_CDK1_ST	Q69YH5	CDCA2	P06493	CDK1	S591	E595Q	595	Missense	distal	4	no	3.716	3.759	EPSD	ICGC;COSMIC	3.158	Up-regulation
CMGC_CDK_CDC2_CDK1_ST	Q69YH5	CDCA2	P06493	CDK1	S591	L589I	589	Missense	proximal	-2	no	3.716	3.763	EPSD	ICGC;COSMIC	3.158	Up-regulation
CMGC_CDK_CDC2_CDK1_ST	Q69YH5	CDCA2	P06493	CDK1	S591	P594T	594	Missense	distal	3	no	3.716	3.732	EPSD	ICGC;COSMIC	3.158	Up-regulation
CMGC_CDK_CDC2_CDK1_ST	Q69YH5	CDCA2	P06493	CDK1	S756	L749R	749	Missense	distal	-7	no	3.415	3.580	EPSD	ICGC;COSMIC	3.158	Up-regulation
CMGC_CDK_CDC2_CDK1_ST	Q69YH5	CDCA2	P06493	CDK1	S756	F752L	752	Missense	distal	-4	no	3.415	3.367	EPSD	ICGC;COSMIC	3.158	Down-regulation
CMGC_CDK_CDC2_CDK1_ST	P04179	SOD2	P06493	CDK1	S106	G109D	109	Missense	distal	3	no	3.273	3.326	PhosphoSitePlus	ICGC;COSMIC	3.158	Up-regulation
CMGC_CDK_CDC2_CDK1_ST	O95251	KAT7	P06493	CDK1	T187	G189D	189	Missense	proximal	2	no	3.333	3.320	EPSD	ICGC;COSMIC	3.158	Down-regulation
CMGC_CDK_CDC2_CDK1_ST	O95251	KAT7	P06493	CDK1	T187	F181C	181	Missense	distal	-6	no	3.333	3.326	EPSD	ICGC;COSMIC	3.158	Down-regulation
CMGC_CDK_CDC2_CDK1_ST	Q8TAP9	MPLKIP	P06493	CDK1	T10	P8S	8	Missense	proximal	-2	no	3.129	3.256	EPSD	ICGC;CCLE	3.158	Gain
CMGC_CDK_CDC2_CDK1_ST	Q8TAP9	MPLKIP	P06493	CDK1	S115	T120K	120	Missense	distal	5	no	3.697	3.723	EPSD	ICGC;COSMIC	3.158	Up-regulation
CMGC_CDK_CDC2_CDK1_ST	Q8TAP9	MPLKIP	P06493	CDK1	S115	P116Q	116	Missense	proximal	1	no	3.697	1.274	EPSD	ICGC;COSMIC	3.158	Loss
CMGC_CDK_CDC2_CDK1_ST	Q8TAP9	MPLKIP	P06493	CDK1	S115	S119C	119	Missense	distal	4	no	3.697	3.651	EPSD	ICGC;COSMIC	3.158	Down-regulation
CMGC_CDK_CDC2_CDK1_ST	Q99666	RGPD6	P06493	CDK1	T799	E798G	798	Missense	proximal	-1	no	3.179	3.306	EPSD	ICGC;COSMIC;CCLE	3.158	Up-regulation
CMGC_CDK_CDC2_CDK1_ST	Q9H4X1	RGCC	P06493	CDK1	S97	P103L	103	Missense	distal	6	no	3.176	3.120	EPSD	ICGC;COSMIC	3.158	Loss
CMGC_CDK_CDC2_CDK1_ST	Q9H4X1	RGCC	P06493	CDK1	S97	A104D	104	Missense	distal	7	no	3.176	3.199	EPSD	ICGC;COSMIC	3.158	Up-regulation
CMGC_CDK_CDC2_CDK1_ST	Q9H4X1	RGCC	P06493	CDK1	T111	A104D	104	Missense	distal	-7	no	3.896	3.808	PhosphoSitePlus	ICGC;COSMIC	3.158	Down-regulation
CMGC_CDK_CDC2_CDK1_ST	Q6PGQ7	BORA	P06493	CDK1	S183	S189Y	189	Missense	distal	6	no	3.308	3.270	EPSD	ICGC	3.158	Down-regulation
CMGC_CDK_CDC2_CDK1_ST	Q6PGQ7	BORA	P06493	CDK1	S183	E178G	178	Missense	distal	-5	no	3.308	3.381	EPSD	ICGC	3.158	Up-regulation
CMGC_CDK_CDC2_CDK1_ST	Q6PGQ7	BORA	P06493	CDK1	S233	L232F	232	Missense	proximal	-1	no	3.564	3.515	EPSD	ICGC	3.158	Down-regulation
CMGC_CDK_CDC2_CDK1_ST	Q6PGQ7	BORA	P06493	CDK1	S252	S250Y	250	Missense	proximal	-2	no	3.157	3.207	EPSD;PhosphoSitePlus	ICGC	3.158	Gain
CMGC_CDK_CDC2_CDK1_ST	Q6PGQ7	BORA	P06493	CDK1	S268	S262R	262	Missense	distal	-6	no	3.196	3.204	EPSD	ICGC	3.158	Up-regulation
CMGC_CDK_CDC2_CDK1_ST	Q6PGQ7	BORA	P06493	CDK1	S325	P326Q	326	Missense	proximal	1	no	3.394	0.972	EPSD	ICGC	3.158	Loss
CMGC_CDK_CDC2_CDK1_ST	Q6PGQ7	BORA	P06493	CDK1	S325	P332T	332	Missense	distal	7	no	3.394	3.396	EPSD	ICGC	3.158	Up-regulation
CMGC_CDK_CDC2_CDK1_ST	Q96EB6	SIRT1	P06493	CDK1	S14	A18G	18	Missense	distal	4	no	3.510	3.342	EPSD	ICGC	3.158	Down-regulation
CMGC_CDK_CDC2_CDK1_ST	Q96EB6	SIRT1	P06493	CDK1	S14	S16P	16	Missense	proximal	2	no	3.510	3.512	EPSD	ICGC	3.158	Up-regulation
CMGC_CDK_CDC2_CDK1_ST	P13639	EEF2	P06493	CDK1	T435	I429S	429	Missense	distal	-6	no	3.884	3.861	EPSD	ICGC	3.158	Down-regulation
CMGC_CDK_CDC2_CDK1_ST	P13639	EEF2	P06493	CDK1	T435	M430I	430	Missense	distal	-5	no	3.884	3.958	EPSD	ICGC;COSMIC	3.158	Up-regulation
CMGC_CDK_CDC2_CDK1_ST	P13639	EEF2	P06493	CDK1	T435	G437V	437	Missense	proximal	2	no	3.884	3.877	EPSD	ICGC;COSMIC	3.158	Down-regulation
CMGC_CDK_CDC2_CDK1_ST	P13639	EEF2	P06493	CDK1	T735	R739C	739	Missense	distal	4	no	3.177	3.112	EPSD	ICGC;COSMIC	3.158	Loss
CMGC_CDK_CDC2_CDK1_ST	P13639	EEF2	P06493	CDK1	T735	E742K	742	Missense	distal	7	no	3.177	3.172	EPSD	ICGC	3.158	Down-regulation
CMGC_CDK_CDC2_CDK1_ST	P13639	EEF2	P06493	CDK1	T735	Q737H	737	Missense	proximal	2	no	3.177	3.185	EPSD	ICGC	3.158	Up-regulation
CMGC_CDK_CDC2_CDK1_ST	P13639	EEF2	P06493	CDK1	T779	A786V	786	Missense	distal	7	no	3.396	3.430	EPSD	ICGC;COSMIC	3.158	Up-regulation
CMGC_CDK_CDC2_CDK1_ST	P13639	EEF2	P06493	CDK1	T779	E772K	772	Missense	distal	-7	no	3.396	3.350	EPSD	ICGC	3.158	Down-regulation
CMGC_CDK_CDC2_CDK1_ST	Q9UJX2	CDC23	P06493	CDK1	T562	E566K	566	Missense	distal	4	no	3.187	3.218	PhosphoSitePlus;EPSD	ICGC;COSMIC;GDSC;CCLE	3.158	Up-regulation
CMGC_CDK_CDC2_CDK1_ST	Q9UJX2	CDC23	P06493	CDK1	T562	E566A	566	Missense	distal	4	no	3.187	3.291	PhosphoSitePlus;EPSD	ICGC;COSMIC	3.158	Up-regulation
CMGC_CDK_CDC2_CDK1_ST	Q9UJX2	CDC23	P06493	CDK1	T562	R557W	557	Missense	distal	-5	no	3.187	3.211	PhosphoSitePlus;EPSD	ICGC	3.158	Up-regulation
CMGC_CDK_CDC2_CDK1_ST	Q9UJX2	CDC23	P06493	CDK1	T562	R557L	557	Missense	distal	-5	no	3.187	3.273	PhosphoSitePlus;EPSD	ICGC;COSMIC	3.158	Up-regulation
CMGC_CDK_CDC2_CDK1_ST	Q13535	ATR	P06493	CDK1	S1007	A1009V	1009	Missense	proximal	2	no	3.895	3.918	EPSD	ICGC	3.158	Up-regulation
CMGC_CDK_CDC2_CDK1_ST	Q9ULW0	TPX2	P06493	CDK1	T147	I151T	151	Missense	distal	4	no	3.081	3.184	EPSD	ICGC;COSMIC	3.158	Gain
CMGC_CDK_CDC2_CDK1_ST	Q9ULW0	TPX2	P06493	CDK1	S186	K182N	182	Missense	distal	-4	no	3.208	3.248	EPSD	ICGC;COSMIC	3.158	Up-regulation
CMGC_CDK_CDC2_CDK1_ST	O95835	LATS1	P06493	CDK1	T255	P248T	248	Missense	distal	-7	no	3.118	3.179	EPSD	ICGC	3.158	Gain
CMGC_CDK_CDC2_CDK1_ST	P29590	PML	P06493	CDK1	S403	P410A	410	Missense	distal	7	no	3.446	3.434	EPSD	ICGC;COSMIC	3.158	Down-regulation
CMGC_CDK_CDC2_CDK1_ST	P29590	PML	P06493	CDK1	S403	V398L	398	Missense	distal	-5	no	3.446	3.473	EPSD	ICGC	3.158	Up-regulation
CMGC_CDK_CDC2_CDK1_ST	P29590	PML	P06493	CDK1	S403	A407S	407	Missense	distal	4	no	3.446	3.386	EPSD	ICGC;COSMIC	3.158	Down-regulation
CMGC_CDK_CDC2_CDK1_ST	P29590	PML	P06493	CDK1	S403	A407T	407	Missense	distal	4	no	3.446	3.394	EPSD	ICGC;COSMIC	3.158	Down-regulation
CMGC_CDK_CDC2_CDK1_ST	Q2M2I8	AAK1	P06493	CDK1	T620	G613R	613	Missense	distal	-7	no	3.179	3.302	EPSD	ICGC	3.158	Up-regulation
CMGC_CDK_CDC2_CDK1_ST	Q2M2I8	AAK1	P06493	CDK1	T620	L619R	619	Missense	proximal	-1	no	3.179	3.040	EPSD	ICGC	3.158	Loss
CMGC_CDK_CDC2_CDK1_ST	P49916	LIG3	P06493	CDK1	S242	S242G	242	Missense	central	0	yes	3.449	0.000	EPSD	ICGC;COSMIC	3.158	Loss
CMGC_CDK_CDC2_CDK1_ST	P49916	LIG3	P06493	CDK1	S913	A909S	909	Missense	distal	-4	no	3.734	3.761	EPSD;PhosphoSitePlus	ICGC;COSMIC	3.158	Up-regulation
CMGC_CDK_CDC2_CDK1_ST	P49916	LIG3	P06493	CDK1	S913	K920R	920	Missense	distal	7	no	3.734	3.732	EPSD;PhosphoSitePlus	ICGC;COSMIC	3.158	Down-regulation
CMGC_CDK_CDC2_CDK1_ST	P49916	LIG3	P06493	CDK1	S913	P914T	914	Missense	proximal	1	no	3.734	1.300	EPSD;PhosphoSitePlus	ICGC;COSMIC	3.158	Loss
CMGC_CDK_CDC2_CDK1_ST	P49916	LIG3	P06493	CDK1	S913	P914Q	914	Missense	proximal	1	no	3.734	1.311	EPSD;PhosphoSitePlus	ICGC;COSMIC	3.158	Loss
CMGC_CDK_CDC2_CDK1_ST	P49916	LIG3	P06493	CDK1	S913	G918R	918	Missense	distal	5	no	3.734	3.542	EPSD;PhosphoSitePlus	ICGC;COSMIC	3.158	Down-regulation
CMGC_CDK_CDC2_CDK1_ST	Q14203	DCTN1	P06493	CDK1	S105	A101T	101	Missense	distal	-4	no	3.163	3.199	EPSD	ICGC;COSMIC	3.158	Up-regulation
CMGC_CDK_CDC2_CDK1_ST	Q14203	DCTN1	P06493	CDK1	S105	S111Y	111	Missense	distal	6	no	3.163	3.124	EPSD	ICGC	3.158	Loss
CMGC_CDK_CDC2_CDK1_ST	Q14203	DCTN1	P06493	CDK1	S203	P199T	199	Missense	distal	-4	no	3.392	3.451	EPSD	ICGC	3.158	Up-regulation
CMGC_CDK_CDC2_CDK1_ST	Q14203	DCTN1	P06493	CDK1	S1180	L1185V	1185	Missense	distal	5	no	3.167	3.103	EPSD	ICGC	3.158	Loss
CMGC_CDK_CDC2_CDK1_ST	O14715	RGPD8	P06493	CDK1	T799	K794N	794	Missense	distal	-5	no	3.179	3.143	EPSD	ICGC;COSMIC	3.158	Loss
CMGC_CDK_CDC2_CDK1_ST	O14715	RGPD8	P06493	CDK1	T799	T804I	804	Missense	distal	5	no	3.179	3.337	EPSD	ICGC;COSMIC	3.158	Up-regulation
CMGC_CDK_CDC2_CDK1_ST	P35251	RFC1	P06493	CDK1	T161	P162H	162	Missense	proximal	1	no	3.642	0.957	EPSD	ICGC;COSMIC	3.158	Loss
CMGC_CDK_CDC2_CDK1_ST	P35251	RFC1	P06493	CDK1	T161	T163K	163	Missense	proximal	2	no	3.642	3.647	EPSD	ICGC	3.158	Up-regulation
CMGC_CDK_CDC2_CDK1_ST	P35251	RFC1	P06493	CDK1	T161	P162T	162	Missense	proximal	1	no	3.642	1.208	EPSD	ICGC	3.158	Loss
CMGC_CDK_CDC2_CDK1_ST	P35251	RFC1	P06493	CDK1	T161	D167E	167	Missense	distal	6	no	3.642	3.644	EPSD	ICGC	3.158	Up-regulation
CMGC_CDK_CDC2_CDK1_ST	O95239	KIF4A	P06493	CDK1	S1225	E1230Q	1230	Missense	distal	5	no	3.430	3.364	EPSD	ICGC;COSMIC	3.158	Down-regulation
CMGC_CDK_CDC2_CDK1_ST	O95239	KIF4A	P06493	CDK1	S1225	C1224F	1224	Missense	proximal	-1	no	3.430	3.466	EPSD	ICGC;COSMIC	3.158	Up-regulation
CMGC_CDK_CDC2_CDK1_ST	P36956	SREBF1	P06493	CDK1	S63	S63F	63	Missense	central	0	yes	3.357	0.000	EPSD	ICGC;COSMIC	3.158	Loss
CMGC_CDK_CDC2_CDK1_ST	P36956	SREBF1	P06493	CDK1	S63	G58D	58	Missense	distal	-5	no	3.357	3.275	EPSD	ICGC;COSMIC	3.158	Down-regulation
CMGC_CDK_CDC2_CDK1_ST	P36956	SREBF1	P06493	CDK1	S63	G57R	57	Missense	distal	-6	no	3.357	3.341	EPSD	ICGC;COSMIC	3.158	Down-regulation
CMGC_CDK_CDC2_CDK1_ST	P36956	SREBF1	P06493	CDK1	S63	A62D	62	Missense	proximal	-1	no	3.357	3.496	EPSD	ICGC	3.158	Up-regulation
CMGC_CDK_CDC2_CDK1_ST	P36956	SREBF1	P06493	CDK1	S63	S68P	68	Missense	distal	5	no	3.357	3.385	EPSD	ICGC;COSMIC	3.158	Up-regulation
CMGC_CDK_CDC2_CDK1_ST	P36956	SREBF1	P06493	CDK1	T105	P111T	111	Missense	distal	6	no	3.336	3.346	EPSD	ICGC;COSMIC	3.158	Up-regulation
CMGC_CDK_CDC2_CDK1_ST	P36956	SREBF1	P06493	CDK1	T105	P99H	99	Missense	distal	-6	no	3.336	3.346	EPSD	ICGC;COSMIC	3.158	Up-regulation
CMGC_CDK_CDC2_CDK1_ST	P36956	SREBF1	P06493	CDK1	T105	P111R	111	Missense	distal	6	no	3.336	3.350	EPSD	ICGC	3.158	Up-regulation
CMGC_CDK_CDC2_CDK1_ST	P36956	SREBF1	P06493	CDK1	T105	S112F	112	Missense	distal	7	no	3.336	3.359	EPSD	ICGC	3.158	Up-regulation
CMGC_CDK_CDC2_CDK1_ST	P17706	PTPN2	P06493	CDK1	S52	N46S	46	Missense	distal	-6	no	3.333	3.325	EPSD	ICGC;COSMIC	3.158	Down-regulation
CMGC_CDK_CDC2_CDK1_ST	P17706	PTPN2	P06493	CDK1	S52	P53Q	53	Missense	proximal	1	no	3.333	0.910	EPSD	ICGC;COSMIC	3.158	Loss
CMGC_CDK_CDC2_CDK1_ST	P17706	PTPN2	P06493	CDK1	S52	Y48H	48	Missense	distal	-4	no	3.333	3.362	EPSD	ICGC;COSMIC	3.158	Up-regulation
CMGC_CDK_CDC2_CDK1_ST	P17706	PTPN2	P06493	CDK1	S304	M309I	309	Missense	distal	5	no	3.397	3.492	PhosphoSitePlus	ICGC;COSMIC	3.158	Up-regulation
CMGC_CDK_CDC2_CDK1_ST	P17706	PTPN2	P06493	CDK1	S304	M309V	309	Missense	distal	5	no	3.397	3.478	PhosphoSitePlus	ICGC;COSMIC	3.158	Up-regulation
CMGC_CDK_CDC2_CDK1_ST	Q13009	TIAM1	P06493	CDK1	T61	S59G	59	Missense	proximal	-2	no	3.365	3.454	EPSD	ICGC;COSMIC	3.158	Up-regulation
CMGC_CDK_CDC2_CDK1_ST	Q13009	TIAM1	P06493	CDK1	T61	S67F	67	Missense	distal	6	no	3.365	3.313	EPSD	ICGC	3.158	Down-regulation
CMGC_CDK_CDC2_CDK1_ST	Q9Y3Z3	SAMHD1	P06493	CDK1	T25	S18R	18	Missense	distal	-7	no	3.616	3.580	EPSD	ICGC;COSMIC	3.158	Down-regulation
CMGC_CDK_CDC2_CDK1_ST	Q9Y3Z3	SAMHD1	P06493	CDK1	T25	D31E	31	Missense	distal	6	no	3.616	3.618	EPSD	ICGC	3.158	Up-regulation
CMGC_CDK_CDC2_CDK1_ST	Q9Y3Z3	SAMHD1	P06493	CDK1	S33	D31E	31	Missense	proximal	-2	no	3.315	3.335	EPSD	ICGC	3.158	Up-regulation
CMGC_CDK_CDC2_CDK1_ST	O00267	SUPT5H	P06493	CDK1	S686	G692C	692	Missense	distal	6	no	3.414	3.436	EPSD	ICGC	3.158	Up-regulation
CMGC_CDK_CDC2_CDK1_ST	O00267	SUPT5H	P06493	CDK1	S686	G690S	690	Missense	distal	4	no	3.414	3.521	EPSD	ICGC	3.158	Up-regulation
CMGC_CDK_CDC2_CDK1_ST	O00267	SUPT5H	P06493	CDK1	S686	P687T	687	Missense	proximal	1	no	3.414	0.980	EPSD	ICGC;COSMIC	3.158	Loss
CMGC_CDK_CDC2_CDK1_ST	O00267	SUPT5H	P06493	CDK1	T791	R798C	798	Missense	distal	7	no	3.587	3.593	EPSD	ICGC;COSMIC	3.158	Up-regulation
CMGC_CDK_CDC2_CDK1_ST	O00267	SUPT5H	P06493	CDK1	T854	P857H	857	Missense	distal	3	no	3.248	3.276	EPSD	ICGC;COSMIC	3.158	Up-regulation
CMGC_CDK_CDC2_CDK1_ST	O00267	SUPT5H	P06493	CDK1	T967	P968S	968	Missense	proximal	1	no	3.199	0.015	EPSD	ICGC;GDSC;CCLE	3.158	Loss
CMGC_CDK_CDC2_CDK1_ST	O00267	SUPT5H	P06493	CDK1	T1034	P1035H	1035	Missense	proximal	1	no	3.753	1.068	EPSD	ICGC;COSMIC	3.158	Loss
CMGC_CDK_CDC2_CDK1_ST	O00267	SUPT5H	P06493	CDK1	T1034	P1035T	1035	Missense	proximal	1	no	3.753	1.319	EPSD	ICGC;COSMIC	3.158	Loss
CMGC_CDK_CDC2_CDK1_ST	Q96KB5	PBK	P06493	CDK1	T9	S11R	11	Missense	proximal	2	no	3.177	3.184	PhosphoSitePlus	ICGC	3.158	Up-regulation
CMGC_CDK_CDC2_CDK1_ST	P10415	BCL2	P06493	CDK1	T74	A81V	81	Missense	distal	7	no	3.764	3.798	EPSD	ICGC;COSMIC	3.158	Up-regulation
CMGC_CDK_CDC2_CDK1_ST	O14745	SLC9A3R1	P06493	CDK1	S280	L273P	273	Missense	distal	-7	no	3.201	3.362	EPSD;PhosphoSitePlus	ICGC;COSMIC	3.158	Up-regulation
CMGC_CDK_CDC2_CDK1_ST	P23769	GATA2	P06493	CDK1	S73	R78H	78	Missense	distal	5	no	3.602	3.668	EPSD	ICGC	3.158	Up-regulation
CMGC_CDK_CDC2_CDK1_ST	P23769	GATA2	P06493	CDK1	S73	S73R	73	Missense	central	0	yes	3.602	0.000	EPSD	ICGC	3.158	Loss
CMGC_CDK_CDC2_CDK1_ST	P23769	GATA2	P06493	CDK1	S73	R67W	67	Missense	distal	-6	no	3.602	3.610	EPSD	ICGC;COSMIC	3.158	Up-regulation
CMGC_CDK_CDC2_CDK1_ST	P23769	GATA2	P06493	CDK1	S73	P74H	74	Missense	proximal	1	no	3.602	0.918	EPSD	ICGC;COSMIC	3.158	Loss
CMGC_CDK_CDC2_CDK1_ST	P23769	GATA2	P06493	CDK1	S73	R78S	78	Missense	distal	5	no	3.602	3.612	EPSD	ICGC;COSMIC	3.158	Up-regulation
CMGC_CDK_CDC2_CDK1_ST	P23769	GATA2	P06493	CDK1	S119	V118M	118	Missense	proximal	-1	no	3.475	3.417	EPSD	ICGC	3.158	Down-regulation
CMGC_CDK_CDC2_CDK1_ST	P23769	GATA2	P06493	CDK1	S119	V118A	118	Missense	proximal	-1	no	3.475	3.275	EPSD	ICGC	3.158	Down-regulation
CMGC_CDK_CDC2_CDK1_ST	P23769	GATA2	P06493	CDK1	T303	R308W	308	Missense	distal	5	no	3.244	3.357	EPSD	ICGC	3.158	Up-regulation
CMGC_CDK_CDC2_CDK1_ST	P23769	GATA2	P06493	CDK1	T303	R308P	308	Missense	distal	5	no	3.244	3.283	EPSD	ICGC;COSMIC	3.158	Up-regulation
CMGC_CDK_CDC2_CDK1_ST	P23769	GATA2	P06493	CDK1	T303	G299W	299	Missense	distal	-4	no	3.244	3.276	EPSD	ICGC;COSMIC	3.158	Up-regulation
CMGC_CDK_CDC2_CDK1_ST	P42166	TMPO	P06493	CDK1	S424	P430H	430	Missense	distal	6	no	3.464	3.459	PhosphoSitePlus	ICGC;COSMIC	3.158	Down-regulation
CMGC_CDK_CDC2_CDK1_ST	P42166	TMPO	P06493	CDK1	S424	P430S	430	Missense	distal	6	no	3.464	3.472	PhosphoSitePlus	ICGC	3.158	Up-regulation
CMGC_CDK_CDC2_CDK1_ST	Q13501	SQSTM1	P06493	CDK1	S28	R21H	21	Missense	distal	-7	no	3.304	3.278	EPSD	ICGC;GDSC;CCLE	3.158	Down-regulation
CMGC_CDK_CDC2_CDK1_ST	Q13501	SQSTM1	P06493	CDK1	S28	P29S	29	Missense	proximal	1	no	3.304	0.119	EPSD	ICGC;COSMIC	3.158	Loss
CMGC_CDK_CDC2_CDK1_ST	Q13501	SQSTM1	P06493	CDK1	S182	R183P	183	Missense	proximal	1	no	-0.167	3.441	EPSD	ICGC;COSMIC	3.158	Gain
CMGC_CDK_CDC2_CDK1_ST	Q8IX03	WWC1	P06493	CDK1	S358	R355C	355	Missense	distal	-3	no	3.522	3.533	EPSD	ICGC;COSMIC	3.158	Up-regulation
CMGC_CDK_CDC2_CDK1_ST	Q8IX03	WWC1	P06493	CDK1	S358	K352R	352	Missense	distal	-6	no	3.522	3.518	EPSD	ICGC;COSMIC	3.158	Down-regulation
CMGC_CDK_CDC2_CDK1_ST	Q8IX03	WWC1	P06493	CDK1	S535	P536Q	536	Missense	proximal	1	no	3.395	0.972	EPSD	ICGC;COSMIC	3.158	Loss
CMGC_CDK_CDC2_CDK1_ST	Q8IX03	WWC1	P06493	CDK1	S535	S539P	539	Missense	distal	4	no	3.395	3.398	EPSD	ICGC;COSMIC	3.158	Up-regulation
CMGC_CDK_CDC2_CDK1_ST	Q8IX03	WWC1	P06493	CDK1	S535	S542T	542	Missense	distal	7	no	3.395	3.398	EPSD	ICGC;COSMIC	3.158	Up-regulation
CMGC_CDK_CDC2_CDK1_ST	Q8IX03	WWC1	P06493	CDK1	S535	S535F	535	Missense	central	0	yes	3.395	0.000	EPSD	ICGC	3.158	Loss
CMGC_CDK_CDC2_CDK1_ST	Q8IX03	WWC1	P06493	CDK1	S535	S541F	541	Missense	distal	6	no	3.395	3.343	EPSD	ICGC	3.158	Down-regulation
CMGC_CDK_CDC2_CDK1_ST	Q8IX03	WWC1	P06493	CDK1	S542	P536Q	536	Missense	distal	-6	no	3.677	3.681	PhosphoSitePlus;EPSD	ICGC;COSMIC	3.158	Up-regulation
CMGC_CDK_CDC2_CDK1_ST	Q8IX03	WWC1	P06493	CDK1	S542	S539P	539	Missense	distal	-3	no	3.677	3.678	PhosphoSitePlus;EPSD	ICGC;COSMIC	3.158	Up-regulation
CMGC_CDK_CDC2_CDK1_ST	Q8IX03	WWC1	P06493	CDK1	S542	S535F	535	Missense	distal	-7	no	3.677	3.531	PhosphoSitePlus;EPSD	ICGC	3.158	Down-regulation
CMGC_CDK_CDC2_CDK1_ST	Q8IX03	WWC1	P06493	CDK1	S542	S541F	541	Missense	proximal	-1	no	3.677	3.830	PhosphoSitePlus;EPSD	ICGC	3.158	Up-regulation
CMGC_CDK_CDC2_CDK1_ST	Q8IX03	WWC1	P06493	CDK1	S548	L555V	555	Missense	distal	7	no	3.675	3.669	EPSD	ICGC	3.158	Down-regulation
CMGC_CDK_CDC2_CDK1_ST	Q8IX03	WWC1	P06493	CDK1	S548	P554L	554	Missense	distal	6	no	3.675	3.619	EPSD	ICGC	3.158	Down-regulation
CMGC_CDK_CDC2_CDK1_ST	Q8IX03	WWC1	P06493	CDK1	S548	S542T	542	Missense	distal	-6	no	3.675	3.674	EPSD	ICGC;COSMIC	3.158	Down-regulation
CMGC_CDK_CDC2_CDK1_ST	Q8IX03	WWC1	P06493	CDK1	S548	S541F	541	Missense	distal	-7	no	3.675	3.529	EPSD	ICGC	3.158	Down-regulation
CMGC_CDK_CDC2_CDK1_ST	Q8IX03	WWC1	P06493	CDK1	T912	R908W	908	Missense	distal	-4	no	3.247	3.206	EPSD	ICGC;COSMIC	3.158	Down-regulation
CMGC_CDK_CDC2_CDK1_ST	Q8IX03	WWC1	P06493	CDK1	T912	V910L	910	Missense	proximal	-2	no	3.247	3.248	EPSD	ICGC	3.158	Up-regulation
CMGC_CDK_CDC2_CDK1_ST	Q14244	MAP7	P06493	CDK1	S209	R212K	212	Missense	distal	3	no	3.353	3.336	PhosphoSitePlus	ICGC;COSMIC	3.158	Down-regulation
CMGC_CDK_CDC2_CDK1_ST	Q14244	MAP7	P06493	CDK1	S315	R311Q	311	Missense	distal	-4	no	3.416	3.435	EPSD	ICGC;COSMIC	3.158	Up-regulation
CMGC_CDK_CDC2_CDK1_ST	Q14244	MAP7	P06493	CDK1	S315	P316A	316	Missense	proximal	1	no	3.416	2.527	EPSD	ICGC;COSMIC	3.158	Loss
CMGC_CDK_CDC2_CDK1_ST	Q14244	MAP7	P06493	CDK1	S315	R311L	311	Missense	distal	-4	no	3.416	3.288	EPSD	ICGC;GDSC;CCLE	3.158	Down-regulation
CMGC_CDK_CDC2_CDK1_ST	P35611	ADD1	P06493	CDK1	S710	S714F	714	Missense	distal	4	no	3.286	3.190	EPSD	ICGC;COSMIC	3.158	Down-regulation
CMGC_CDK_CDC2_CDK1_ST	P35611	ADD1	P06493	CDK1	S710	P711S	711	Missense	proximal	1	no	3.286	0.102	EPSD	ICGC;COSMIC	3.158	Loss
CMGC_CDK_CDC2_CDK1_ST	P35611	ADD1	P06493	CDK1	S710	D708N	708	Missense	proximal	-2	no	3.286	3.297	EPSD	ICGC;COSMIC	3.158	Up-regulation
CMGC_CDK_CDC2_CDK1_ST	P35611	ADD1	P06493	CDK1	S710	P715L	715	Missense	distal	5	no	3.286	3.471	EPSD	ICGC;COSMIC	3.158	Up-regulation
CMGC_CDK_CDC2_CDK1_ST	P35611	ADD1	P06493	CDK1	S714	S714F	714	Missense	central	0	yes	3.399	0.000	EPSD	ICGC;COSMIC	3.158	Loss
CMGC_CDK_CDC2_CDK1_ST	P35611	ADD1	P06493	CDK1	S714	D708N	708	Missense	distal	-6	no	3.399	3.397	EPSD	ICGC;COSMIC	3.158	Down-regulation
CMGC_CDK_CDC2_CDK1_ST	P35611	ADD1	P06493	CDK1	S714	P715L	715	Missense	proximal	1	no	3.399	-0.287	EPSD	ICGC;COSMIC	3.158	Loss
CMGC_CDK_CDC2_CDK1_ST	O15530	PDPK1	P06493	CDK1	S231	S231A	231	Missense	central	0	yes	3.300	0.000	EPSD	ICGC;COSMIC	3.158	Loss
CMGC_CDK_CDC2_CDK1_ST	Q96T23	RSF1	P06493	CDK1	S622	S622L	622	Missense	central	0	yes	3.296	0.000	EPSD	ICGC;COSMIC	3.158	Loss
CMGC_CDK_CDC2_CDK1_ST	Q96T23	RSF1	P06493	CDK1	S629	S622L	622	Missense	distal	-7	no	3.551	3.350	EPSD	ICGC;COSMIC	3.158	Down-regulation
CMGC_CDK_CDC2_CDK1_ST	P24864	CCNE1	P06493	CDK1	S103	P106H	106	Missense	distal	3	no	3.241	3.270	EPSD	ICGC;COSMIC	3.158	Up-regulation
CMGC_CDK_CDC2_CDK1_ST	P24864	CCNE1	P06493	CDK1	S103	V107A	107	Missense	distal	4	no	3.241	3.377	EPSD	ICGC;COSMIC	3.158	Up-regulation
CMGC_CDK_CDC2_CDK1_ST	P24864	CCNE1	P06493	CDK1	T395	S399I	399	Missense	distal	4	no	3.467	3.373	EPSD	ICGC;COSMIC	3.158	Down-regulation
CMGC_CDK_CDC2_CDK1_ST	P24864	CCNE1	P06493	CDK1	T395	S399R	399	Missense	distal	4	no	3.467	3.485	EPSD	ICGC;COSMIC;GDSC;CCLE	3.158	Up-regulation
CMGC_CDK_CDC2_CDK1_ST	P24864	CCNE1	P06493	CDK1	T395	G400D	400	Missense	distal	5	no	3.467	3.373	EPSD	ICGC;COSMIC	3.158	Down-regulation
CMGC_CDK_CDC2_CDK1_ST	P24864	CCNE1	P06493	CDK1	T395	L394I	394	Missense	proximal	-1	no	3.467	3.464	EPSD	ICGC	3.158	Down-regulation
CMGC_CDK_CDC2_CDK1_ST	O43521	BCL2L11	P06493	CDK1	S59	G62S	62	Missense	distal	3	no	3.382	3.504	EPSD	ICGC;COSMIC	3.158	Up-regulation
CMGC_CDK_CDC2_CDK1_ST	O43521	BCL2L11	P06493	CDK1	S59	P56L	56	Missense	distal	-3	no	3.382	3.350	EPSD	ICGC	3.158	Down-regulation
CMGC_CDK_CDC2_CDK1_ST	O43521	BCL2L11	P06493	CDK1	S59	G52W	52	Missense	distal	-7	no	3.382	3.434	EPSD	ICGC;COSMIC	3.158	Up-regulation
CMGC_CDK_CDC2_CDK1_ST	O43521	BCL2L11	P06493	CDK1	S69	G62S	62	Missense	distal	-7	no	3.155	3.314	EPSD	ICGC;COSMIC	3.158	Gain
CMGC_CDK_CDC2_CDK1_ST	O43521	BCL2L11	P06493	CDK1	T116	K112T	112	Missense	distal	-4	no	3.142	3.263	EPSD	ICGC;COSMIC	3.158	Gain
CMGC_CDK_CDC2_CDK1_ST	Q96C36	PYCR2	P06493	CDK1	S233	L227I	227	Missense	distal	-6	no	3.541	3.535	EPSD	ICGC	3.158	Down-regulation
CMGC_CDK_CDC2_CDK1_ST	Q96C36	PYCR2	P06493	CDK1	T301	T296K	296	Missense	distal	-5	no	3.300	3.387	EPSD	ICGC	3.158	Up-regulation
CMGC_CDK_CDC2_CDK1_ST	Q96C36	PYCR2	P06493	CDK1	T301	L308I	308	Missense	distal	7	no	3.300	3.297	EPSD	ICGC	3.158	Down-regulation
CMGC_CDK_CDC2_CDK1_ST	Q06413	MEF2C	P06493	CDK1	S110	D105N	105	Missense	distal	-5	no	3.200	3.203	EPSD	ICGC;COSMIC	3.158	Up-regulation
CMGC_CDK_CDC2_CDK1_ST	Q06413	MEF2C	P06493	CDK1	S110	G108C	108	Missense	proximal	-2	no	3.200	3.127	EPSD	ICGC;COSMIC	3.158	Loss
CMGC_CDK_CDC2_CDK1_ST	Q06413	MEF2C	P06493	CDK1	S110	D104E	104	Missense	distal	-6	no	3.200	3.199	EPSD	ICGC;COSMIC	3.158	Down-regulation
CMGC_CDK_CDC2_CDK1_ST	Q06413	MEF2C	P06493	CDK1	S110	Y117H	117	Missense	distal	7	no	3.200	3.193	EPSD	ICGC	3.158	Down-regulation
CMGC_CDK_CDC2_CDK1_ST	Q06413	MEF2C	P06493	CDK1	S110	S110I	110	Missense	central	0	yes	3.200	0.000	EPSD	ICGC;COSMIC	3.158	Loss
CMGC_CDK_CDC2_CDK1_ST	Q06413	MEF2C	P06493	CDK1	S183	H188R	188	Missense	distal	5	no	3.587	3.522	EPSD	ICGC;COSMIC	3.158	Down-regulation
CMGC_CDK_CDC2_CDK1_ST	Q06413	MEF2C	P06493	CDK1	S183	P190L	190	Missense	distal	7	no	3.587	3.615	EPSD	ICGC;COSMIC	3.158	Up-regulation
CMGC_CDK_CDC2_CDK1_ST	Q06413	MEF2C	P06493	CDK1	S183	R189Q	189	Missense	distal	6	no	3.587	3.570	EPSD	ICGC;COSMIC	3.158	Down-regulation
CMGC_CDK_CDC2_CDK1_ST	Q06413	MEF2C	P06493	CDK1	S183	P190S	190	Missense	distal	7	no	3.587	3.585	EPSD	ICGC;COSMIC	3.158	Down-regulation
CMGC_CDK_CDC2_CDK1_ST	Q06413	MEF2C	P06493	CDK1	S183	S183F	183	Missense	central	0	yes	3.587	0.000	EPSD	ICGC;COSMIC	3.158	Loss
CMGC_CDK_CDC2_CDK1_ST	Q06413	MEF2C	P06493	CDK1	S240	L246V	246	Missense	distal	6	no	3.432	3.459	EPSD	ICGC;COSMIC	3.158	Up-regulation
CMGC_CDK_CDC2_CDK1_ST	Q06413	MEF2C	P06493	CDK1	S396	P397R	397	Missense	proximal	1	no	3.246	-0.363	PhosphoSitePlus	ICGC;COSMIC	3.158	Loss
CMGC_CDK_CDC2_CDK1_ST	Q06413	MEF2C	P06493	CDK1	S396	P397T	397	Missense	proximal	1	no	3.246	0.813	PhosphoSitePlus	ICGC;COSMIC	3.158	Loss
CMGC_CDK_CDC2_CDK1_ST	O43663	PRC1	P06493	CDK1	S513	Y511C	511	Missense	proximal	-2	no	3.253	3.219	EPSD	ICGC;COSMIC	3.158	Down-regulation
CMGC_CDK_CDC2_CDK1_ST	O43663	PRC1	P06493	CDK1	S513	R517Q	517	Missense	distal	4	no	3.253	3.234	EPSD	ICGC;COSMIC;GDSC;CCLE	3.158	Down-regulation
CMGC_CDK_CDC2_CDK1_ST	O43663	PRC1	P06493	CDK1	S513	P520L	520	Missense	distal	7	no	3.253	3.281	EPSD	ICGC	3.158	Up-regulation
CMGC_CDK_CDC2_CDK1_ST	O43663	PRC1	P06493	CDK1	S513	P514L	514	Missense	proximal	1	no	3.253	-0.434	EPSD	ICGC	3.158	Loss
CMGC_CDK_CDC2_CDK1_ST	P33993	MCM7	P06493	CDK1	S365	Q364K	364	Missense	proximal	-1	no	3.344	3.425	EPSD	ICGC	3.158	Up-regulation
CMGC_CDK_CDC2_CDK1_ST	P33993	MCM7	P06493	CDK1	S365	G360V	360	Missense	distal	-5	no	3.344	3.334	EPSD	ICGC	3.158	Down-regulation
CMGC_CDK_CDC2_CDK1_ST	P33993	MCM7	P06493	CDK1	S365	R367P	367	Missense	proximal	2	no	3.344	3.338	EPSD	ICGC;COSMIC	3.158	Down-regulation
CMGC_CDK_CDC2_CDK1_ST	P33993	MCM7	P06493	CDK1	S365	R372W	372	Missense	distal	7	no	3.344	3.351	EPSD	ICGC	3.158	Up-regulation
CMGC_CDK_CDC2_CDK1_ST	P33993	MCM7	P06493	CDK1	S365	G360E	360	Missense	distal	-5	no	3.344	3.271	EPSD	ICGC;COSMIC	3.158	Down-regulation
CMGC_CDK_CDC2_CDK1_ST	O75170	PPP6R2	P06493	CDK1	T430	E429Q	429	Missense	proximal	-1	no	3.440	3.398	EPSD	ICGC;COSMIC	3.158	Down-regulation
CMGC_CDK_CDC2_CDK1_ST	P22234	PAICS	P06493	CDK1	S27	D26G	26	Missense	proximal	-1	no	3.186	3.321	PhosphoSitePlus	ICGC;COSMIC	3.158	Up-regulation
CMGC_CDK_CDC2_CDK1_ST	Q2NKX8	ERCC6L	P06493	CDK1	S755	P750L	750	Missense	distal	-5	no	3.155	3.276	EPSD	ICGC;COSMIC	3.158	Gain
CMGC_CDK_CDC2_CDK1_ST	Q2NKX8	ERCC6L	P06493	CDK1	S946	P942L	942	Missense	distal	-4	no	3.475	3.332	EPSD	ICGC	3.158	Down-regulation
CMGC_CDK_CDC2_CDK1_ST	Q2NKX8	ERCC6L	P06493	CDK1	S1069	G1072A	1072	Missense	distal	3	no	3.079	3.254	EPSD	ICGC;COSMIC	3.158	Gain
CMGC_CDK_CDC2_CDK1_ST	Q2NKX8	ERCC6L	P06493	CDK1	S1188	A1193V	1193	Missense	distal	5	no	3.965	4.172	EPSD	ICGC	3.158	Up-regulation
CMGC_CDK_CDC2_CDK1_ST	P49821	NDUFV1	P06493	CDK1	T383	G388C	388	Missense	distal	5	no	3.629	3.545	PhosphoSitePlus	ICGC;COSMIC	3.158	Down-regulation
CMGC_CDK_CDC2_CDK1_ST	P13051	UNG	P06493	CDK1	T60	P65L	65	Missense	distal	5	no	3.029	3.214	EPSD	ICGC;COSMIC	3.158	Gain
CMGC_CDK_CDC2_CDK1_ST	P18858	LIG1	P06493	CDK1	T233	T227A	227	Missense	distal	-6	no	3.337	3.336	EPSD	ICGC;COSMIC	3.158	Down-regulation
CMGC_CDK_CDC2_CDK1_ST	O00399	DCTN6	P06493	CDK1	T71	D73N	73	Missense	proximal	2	no	3.921	3.917	EPSD	ICGC;COSMIC	3.158	Down-regulation
CMGC_CDK_CDC2_CDK1_ST	Q9Y4H2	IRS2	P06493	CDK1	S3	R6L	6	Missense	distal	3	no	3.270	3.017	EPSD	ICGC;COSMIC	3.158	Loss
CMGC_CDK_CDC2_CDK1_ST	Q9Y4H2	IRS2	P06493	CDK1	S491	D494A	494	Missense	distal	3	no	3.116	3.239	EPSD	ICGC	3.158	Gain
CMGC_CDK_CDC2_CDK1_ST	Q9Y4H2	IRS2	P06493	CDK1	T527	G534S	534	Missense	distal	7	no	3.374	3.347	EPSD	ICGC;COSMIC	3.158	Down-regulation
CMGC_CDK_CDC2_CDK1_ST	Q9Y4H2	IRS2	P06493	CDK1	T657	T657M	657	Missense	central	0	yes	3.213	0.000	EPSD	ICGC;COSMIC	3.158	Loss
CMGC_CDK_CDC2_CDK1_ST	Q9Y4H2	IRS2	P06493	CDK1	S736	A733T	733	Missense	distal	-3	no	3.437	3.400	EPSD	ICGC;COSMIC	3.158	Down-regulation
CMGC_CDK_CDC2_CDK1_ST	Q9Y4H2	IRS2	P06493	CDK1	T844	L839P	839	Missense	distal	-5	no	3.324	3.203	EPSD	ICGC;COSMIC	3.158	Down-regulation
CMGC_CDK_CDC2_CDK1_ST	Q9Y4H2	IRS2	P06493	CDK1	S915	P910S	910	Missense	distal	-5	no	3.283	3.261	EPSD	ICGC;COSMIC	3.158	Down-regulation
CMGC_CDK_CDC2_CDK1_ST	Q9Y4H2	IRS2	P06493	CDK1	S915	P913L	913	Missense	proximal	-2	no	3.283	3.456	EPSD	ICGC;COSMIC	3.158	Up-regulation
CMGC_CDK_CDC2_CDK1_ST	Q9Y4H2	IRS2	P06493	CDK1	S985	F983L	983	Missense	proximal	-2	no	3.353	3.333	EPSD	ICGC;COSMIC	3.158	Down-regulation
CMGC_CDK_CDC2_CDK1_ST	Q9Y4H2	IRS2	P06493	CDK1	S985	S984C	984	Missense	proximal	-1	no	3.353	3.470	EPSD	ICGC;COSMIC	3.158	Up-regulation
CMGC_CDK_CDC2_CDK1_ST	Q9Y4H2	IRS2	P06493	CDK1	T1082	A1080V	1080	Missense	proximal	-2	no	3.332	3.497	EPSD	ICGC;COSMIC	3.158	Up-regulation
CMGC_CDK_CDC2_CDK1_ST	Q9Y4H2	IRS2	P06493	CDK1	T1082	Q1085K	1085	Missense	distal	3	no	3.332	3.363	EPSD	ICGC;COSMIC	3.158	Up-regulation
CMGC_CDK_CDC2_CDK1_ST	Q9Y4H2	IRS2	P06493	CDK1	T1082	P1084S	1084	Missense	proximal	2	no	3.332	3.330	EPSD	ICGC	3.158	Down-regulation
CMGC_CDK_CDC2_CDK1_ST	Q9Y4H2	IRS2	P06493	CDK1	T1082	T1082P	1082	Missense	central	0	yes	3.332	0.000	EPSD	ICGC;COSMIC	3.158	Loss
CMGC_CDK_CDC2_CDK1_ST	Q8WX93	PALLD	P06493	CDK1	T147	K153N	153	Missense	distal	6	no	3.491	3.494	EPSD	ICGC	3.158	Up-regulation
CMGC_CDK_CDC2_CDK1_ST	Q8WX93	PALLD	P06493	CDK1	S641	P648H	648	Missense	distal	7	no	3.856	3.863	EPSD;PhosphoSitePlus	ICGC;COSMIC	3.158	Up-regulation
CMGC_CDK_CDC2_CDK1_ST	O60285	NUAK1	P06493	CDK1	S22	V27G	27	Missense	distal	5	no	3.211	3.243	EPSD	ICGC;COSMIC	3.158	Up-regulation
CMGC_CDK_CDC2_CDK1_ST	O60285	NUAK1	P06493	CDK1	S325	S323F	323	Missense	proximal	-2	no	3.139	3.207	EPSD	ICGC	3.158	Gain
CMGC_CDK_CDC2_CDK1_ST	O60285	NUAK1	P06493	CDK1	S325	R330W	330	Missense	distal	5	no	3.139	3.252	EPSD	ICGC;COSMIC	3.158	Gain
CMGC_CDK_CDC2_CDK1_ST	O60285	NUAK1	P06493	CDK1	S445	E449Q	449	Missense	distal	4	no	3.188	3.231	PhosphoSitePlus	ICGC;COSMIC	3.158	Up-regulation
CMGC_CDK_CDC2_CDK1_ST	O60285	NUAK1	P06493	CDK1	S445	V440M	440	Missense	distal	-5	no	3.188	3.127	PhosphoSitePlus	ICGC	3.158	Loss
CMGC_CDK_CDC2_CDK1_ST	O60285	NUAK1	P06493	CDK1	S445	P443Q	443	Missense	proximal	-2	no	3.188	3.327	PhosphoSitePlus	ICGC;COSMIC	3.158	Up-regulation
CMGC_CDK_CDC2_CDK1_ST	O60285	NUAK1	P06493	CDK1	S445	L442I	442	Missense	distal	-3	no	3.188	3.179	PhosphoSitePlus	ICGC;COSMIC	3.158	Down-regulation
CMGC_CDK_CDC2_CDK1_ST	O60285	NUAK1	P06493	CDK1	S455	S455N	455	Missense	central	0	yes	3.500	0.000	EPSD	ICGC;COSMIC	3.158	Loss
CMGC_CDK_CDC2_CDK1_ST	O60285	NUAK1	P06493	CDK1	S455	E449Q	449	Missense	distal	-6	no	3.500	3.496	EPSD	ICGC;COSMIC	3.158	Down-regulation
CMGC_CDK_CDC2_CDK1_ST	O60285	NUAK1	P06493	CDK1	S542	P543R	543	Missense	proximal	1	no	3.304	-0.305	EPSD	ICGC;COSMIC	3.158	Loss
CMGC_CDK_CDC2_CDK1_ST	O60285	NUAK1	P06493	CDK1	S542	A539D	539	Missense	distal	-3	no	3.304	3.245	EPSD	ICGC	3.158	Down-regulation
CMGC_CDK_CDC2_CDK1_ST	P00338	LDHA	P06493	CDK1	T18	K22N	22	Missense	distal	4	no	3.951	3.947	EPSD	ICGC;COSMIC	3.158	Down-regulation
CMGC_CDK_CDC2_CDK1_ST	P00338	LDHA	P06493	CDK1	S128	I121V	121	Missense	distal	-7	no	3.205	3.233	EPSD	ICGC;COSMIC	3.158	Up-regulation
CMGC_CDK_CDC2_CDK1_ST	P00338	LDHA	P06493	CDK1	S128	C131F	131	Missense	distal	3	no	3.205	3.123	EPSD	ICGC	3.158	Loss
CMGC_CDK_CDC2_CDK1_ST	P00338	LDHA	P06493	CDK1	S128	L133F	133	Missense	distal	5	no	3.205	3.159	EPSD	ICGC	3.158	Down-regulation
CMGC_CDK_CDC2_CDK1_ST	P00338	LDHA	P06493	CDK1	S128	P122L	122	Missense	distal	-6	no	3.205	3.232	EPSD	ICGC;COSMIC	3.158	Up-regulation
CMGC_CDK_CDC2_CDK1_ST	P00338	LDHA	P06493	CDK1	S128	P129S	129	Missense	proximal	1	no	3.205	0.021	EPSD	ICGC;COSMIC	3.158	Loss
CMGC_CDK_CDC2_CDK1_ST	O75152	ZC3H11A	P06493	CDK1	S495	P496S	496	Missense	proximal	1	no	3.339	0.155	EPSD	ICGC;COSMIC	3.158	Loss
CMGC_CDK_CDC2_CDK1_ST	P20338	RAB4A	P06493	CDK1	S204	Q209L	209	Missense	distal	5	no	3.259	3.458	PhosphoSitePlus	ICGC;COSMIC	3.158	Up-regulation
CMGC_CDK_CDC2_CDK1_ST	P20338	RAB4A	P06493	CDK1	S204	A210S	210	Missense	distal	6	no	3.259	3.249	PhosphoSitePlus	ICGC	3.158	Down-regulation
CMGC_CDK_CDC2_CDK1_ST	Q8IXJ6	SIRT2	P06493	CDK1	T280	L278F	278	Missense	proximal	-2	no	3.535	3.556	EPSD	ICGC;COSMIC	3.158	Up-regulation
CMGC_CDK_CDC2_CDK1_ST	Q9H9S0	NANOG	P06493	CDK1	S65	T70P	70	Missense	distal	5	no	3.327	3.349	EPSD;PhosphoSitePlus	ICGC;COSMIC	3.158	Up-regulation
CMGC_CDK_CDC2_CDK1_ST	Q9H9S0	NANOG	P06493	CDK1	S65	P66H	66	Missense	proximal	1	no	3.327	0.642	EPSD;PhosphoSitePlus	ICGC;COSMIC;CCLE	3.158	Loss
CMGC_CDK_CDC2_CDK1_ST	Q9H9S0	NANOG	P06493	CDK1	S65	D59N	59	Missense	distal	-6	no	3.327	3.325	EPSD;PhosphoSitePlus	ICGC;COSMIC	3.158	Down-regulation
CMGC_CDK_CDC2_CDK1_ST	P23396	RPS3	P06493	CDK1	T42	R45S	45	Missense	distal	3	no	3.626	3.556	EPSD	ICGC	3.158	Down-regulation
CMGC_CDK_CDC2_CDK1_ST	P23396	RPS3	P06493	CDK1	T42	R40Q	40	Missense	proximal	-2	no	3.626	3.572	EPSD	ICGC;COSMIC	3.158	Down-regulation
CMGC_CDK_CDC2_CDK1_ST	P23396	RPS3	P06493	CDK1	T42	G36R	36	Missense	distal	-6	no	3.626	3.611	EPSD	ICGC;COSMIC	3.158	Down-regulation
CMGC_CDK_CDC2_CDK1_ST	P04637	TP53	P06493	CDK1	S33	P34L	34	Missense	proximal	1	no	3.447	-0.239	EPSD	ICGC;COSMIC	3.158	Loss
CMGC_CDK_CDC2_CDK1_ST	P04637	TP53	P06493	CDK1	S33	S33F	33	Missense	central	0	yes	3.447	0.000	EPSD	ICGC;COSMIC	3.158	Loss
CMGC_CDK_CDC2_CDK1_ST	P04637	TP53	P06493	CDK1	S33	N30I	30	Missense	distal	-3	no	3.447	3.424	EPSD	ICGC	3.158	Down-regulation
CMGC_CDK_CDC2_CDK1_ST	P04637	TP53	P06493	CDK1	T81	A88D	88	Missense	distal	7	no	3.467	3.491	EPSD	ICGC	3.158	Up-regulation
CMGC_CDK_CDC2_CDK1_ST	P04637	TP53	P06493	CDK1	T81	P87Q	87	Missense	distal	6	no	3.467	3.464	EPSD	ICGC;COSMIC	3.158	Down-regulation
CMGC_CDK_CDC2_CDK1_ST	Q8NEB9	PIK3C3	P06493	CDK1	S455	L450F	450	Missense	distal	-5	no	3.630	3.596	EPSD	ICGC	3.158	Down-regulation
CMGC_CDK_CDC2_CDK1_ST	Q8NEB9	PIK3C3	P06493	CDK1	S455	P457H	457	Missense	proximal	2	no	3.630	3.640	EPSD	ICGC;COSMIC	3.158	Up-regulation
CMGC_CDK_CDC2_CDK1_ST	Q8NEB9	PIK3C3	P06493	CDK1	S455	P457T	457	Missense	proximal	2	no	3.630	3.628	EPSD	ICGC;COSMIC	3.158	Down-regulation
CMGC_CDK_CDC2_CDK1_ST	Q8TD19	NEK9	P06493	CDK1	S29	P32T	32	Missense	distal	3	no	3.172	3.188	EPSD	ICGC	3.158	Up-regulation
CMGC_CDK_CDC2_CDK1_ST	Q8TD19	NEK9	P06493	CDK1	S29	G31E	31	Missense	proximal	2	no	3.172	3.159	EPSD	ICGC	3.158	Down-regulation
CMGC_CDK_CDC2_CDK1_ST	Q8TD19	NEK9	P06493	CDK1	T214	A208D	208	Missense	distal	-6	no	3.620	3.632	EPSD	ICGC;COSMIC	3.158	Up-regulation
CMGC_CDK_CDC2_CDK1_ST	Q8TD19	NEK9	P06493	CDK1	T358	P359S	359	Missense	proximal	1	no	3.298	0.113	EPSD	ICGC;COSMIC	3.158	Loss
CMGC_CDK_CDC2_CDK1_ST	Q8TD19	NEK9	P06493	CDK1	T358	S357Y	357	Missense	proximal	-1	no	3.298	3.447	EPSD	ICGC	3.158	Up-regulation
CMGC_CDK_CDC2_CDK1_ST	Q8TD19	NEK9	P06493	CDK1	S793	R786Q	786	Missense	distal	-7	no	3.343	3.350	EPSD	ICGC;COSMIC;GDSC	3.158	Up-regulation
CMGC_CDK_CDC2_CDK1_ST	Q8TD19	NEK9	P06493	CDK1	S793	R786L	786	Missense	distal	-7	no	3.343	3.178	EPSD	ICGC;COSMIC	3.158	Down-regulation
CMGC_CDK_CDC2_CDK1_ST	Q8TD19	NEK9	P06493	CDK1	S829	P828T	828	Missense	proximal	-1	no	3.256	3.178	EPSD	ICGC;COSMIC	3.158	Down-regulation
CMGC_CDK_CDC2_CDK1_ST	Q8TD19	NEK9	P06493	CDK1	S829	S829F	829	Missense	central	0	yes	3.256	0.000	EPSD	ICGC	3.158	Loss
CMGC_CDK_CDC2_CDK1_ST	Q8TD19	NEK9	P06493	CDK1	T883	A889E	889	Missense	distal	6	no	3.168	3.136	EPSD	ICGC	3.158	Loss
CMGC_CDK_CDC2_CDK1_ST	Q8TD19	NEK9	P06493	CDK1	T886	A889E	889	Missense	distal	3	no	4.291	4.186	EPSD	ICGC	3.158	Down-regulation
CMGC_CDK_CDC2_CDK1_ST	Q8TD19	NEK9	P06493	CDK1	T886	A891V	891	Missense	distal	5	no	4.291	4.498	EPSD	ICGC	3.158	Up-regulation
CMGC_CDK_CDC2_CDK1_ST	Q02952	AKAP12	P06493	CDK1	S514	E507K	507	Missense	distal	-7	no	3.926	3.881	EPSD	ICGC;COSMIC	3.158	Down-regulation
AGC_PKG_PRKG1_ST	Q13976	PRKG1	Q13976-2	PRKG1	S27	E23K	23	Missense	distal	-4	no	10.846	11.507	EPSD	ICGC	7.092	Up-regulation
AGC_PKG_PRKG1_ST	Q13153	PAK1	Q13976-2	PRKG1	S21	G27S	27	Missense	distal	6	no	8.946	8.803	PhosphoSitePlus	ICGC;COSMIC	7.092	Down-regulation
AGC_PKG_PRKG1_ST	Q13153	PAK1	Q13976-2	PRKG1	S21	P16L	16	Missense	distal	-5	no	8.946	9.067	PhosphoSitePlus	ICGC;COSMIC	7.092	Up-regulation
AGC_PKG_PRKG1_ST	Q13153	PAK1	Q13976-2	PRKG1	S21	T22N	22	Missense	proximal	1	no	8.946	8.792	PhosphoSitePlus	ICGC	7.092	Down-regulation
AGC_PKG_PRKG1_ST	Q13153	PAK1	Q13976-2	PRKG1	S137	T136K	136	Missense	proximal	-1	no	8.034	8.078	EPSD	ICGC	7.092	Up-regulation
AGC_PKG_PRKG1_ST	Q13153	PAK1	Q13976-2	PRKG1	S139	T136K	136	Missense	distal	-3	no	4.910	7.718	EPSD	ICGC	7.092	Gain
AGC_PKG_PRKG1_ST	Q13153	PAK1	Q13976-2	PRKG1	S165	K162R	162	Missense	distal	-3	no	5.710	8.068	EPSD	ICGC;COSMIC	7.092	Gain
AGC_PKG_PRKG1_ST	Q13153	PAK1	Q13976-2	PRKG1	S249	Q242K	242	Missense	distal	-7	no	8.062	8.272	EPSD	ICGC	7.092	Up-regulation
AGC_PKG_PRKG1_ST	Q13153	PAK1	Q13976-2	PRKG1	T271	G277A	277	Missense	distal	6	no	7.347	7.236	EPSD	ICGC;COSMIC	7.092	Down-regulation
AGC_PKG_PRKG1_ST	Q13153	PAK1	Q13976-2	PRKG1	T271	T271K	271	Missense	central	0	yes	7.347	0.000	EPSD	ICGC;COSMIC	7.092	Loss
AGC_PKG_PRKG1_ST	Q13153	PAK1	Q13976-2	PRKG1	S422	T415N	415	Missense	distal	-7	no	9.274	8.879	EPSD	ICGC;COSMIC	7.092	Down-regulation
AGC_PKG_PRKG1_ST	Q13153	PAK1	Q13976-2	PRKG1	S422	P416L	416	Missense	distal	-6	no	9.274	8.963	EPSD	ICGC	7.092	Down-regulation
AGC_PKG_PRKG1_ST	Q13153	PAK1	Q13976-2	PRKG1	T423	P416L	416	Missense	distal	-7	no	8.832	8.216	EPSD	ICGC	7.092	Down-regulation
AGC_PKG_PRKG1_ST	Q13153	PAK1	Q13976-2	PRKG1	S528	P532L	532	Missense	distal	4	no	8.202	8.302	EPSD	ICGC;COSMIC	7.092	Up-regulation
AGC_PKG_PRKG1_ST	Q14847	LASP1	Q13976-2	PRKG1	S146	M139I	139	Missense	distal	-7	no	12.899	11.777	PhosphoSitePlus	ICGC;COSMIC	7.092	Down-regulation
STE_STE20_PAKB_PAK4_ST	O43623	SNAI2	O96013	PAK4	S100	S95T	95	Missense	distal	-5	no	17.763	17.416	EPSD	ICGC;COSMIC	14.946	Down-regulation
STE_STE20_PAKB_PAK4_ST	O43623	SNAI2	O96013	PAK4	S158	Q154K	154	Missense	distal	-4	no	19.917	20.520	PhosphoSitePlus	ICGC	14.946	Up-regulation
STE_STE20_PAKB_PAK4_ST	O43623	SNAI2	O96013	PAK4	S158	D165E	165	Missense	distal	7	no	19.917	19.779	PhosphoSitePlus	ICGC	14.946	Down-regulation
STE_STE20_PAKB_PAK4_ST	O43623	SNAI2	O96013	PAK4	S170	V169L	169	Missense	proximal	-1	no	15.232	16.374	EPSD	ICGC;COSMIC	14.946	Up-regulation
STE_STE20_PAKB_PAK4_ST	O43623	SNAI2	O96013	PAK4	S170	H177N	177	Missense	distal	7	no	15.232	15.324	EPSD	ICGC	14.946	Up-regulation
STE_STE20_PAKB_PAK4_ST	O43623	SNAI2	O96013	PAK4	S170	S170R	170	Missense	central	0	yes	15.232	0.000	EPSD	ICGC	14.946	Loss
STE_STE20_PAKB_PAK4_ST	O43623	SNAI2	O96013	PAK4	S170	D165E	165	Missense	distal	-5	no	15.232	15.313	EPSD	ICGC	14.946	Up-regulation
STE_STE20_PAKB_PAK4_ST	O43623	SNAI2	O96013	PAK4	S170	G172C	172	Missense	proximal	2	no	15.232	15.085	EPSD	ICGC	14.946	Down-regulation
STE_STE20_PAKB_PAK4_ST	O43623	SNAI2	O96013	PAK4	S247	M253I	253	Missense	distal	6	no	15.232	15.490	EPSD	ICGC;COSMIC	14.946	Up-regulation
STE_STE20_PAKB_PAK4_ST	O43623	SNAI2	O96013	PAK4	S251	M253I	253	Missense	proximal	2	no	18.576	18.316	EPSD	ICGC;COSMIC	14.946	Down-regulation
STE_STE20_PAKB_PAK4_ST	O96013	PAK4	O96013	PAK4	S99	R96C	96	Missense	distal	-3	no	17.891	10.369	EPSD	ICGC;COSMIC	14.946	Loss
STE_STE20_PAKB_PAK4_ST	O96013	PAK4	O96013	PAK4	S99	R101W	101	Missense	proximal	2	no	17.891	18.019	EPSD	ICGC;COSMIC	14.946	Up-regulation
STE_STE20_PAKB_PAK4_ST	O96013	PAK4	O96013	PAK4	S104	R110L	110	Missense	distal	6	no	16.271	16.957	EPSD	ICGC	14.946	Up-regulation
STE_STE20_PAKB_PAK4_ST	O96013	PAK4	O96013	PAK4	S104	R101W	101	Missense	distal	-3	no	16.271	9.346	EPSD	ICGC;COSMIC	14.946	Loss
STE_STE20_PAKB_PAK4_ST	O96013	PAK4	O96013	PAK4	S142	R135Q	135	Missense	distal	-7	no	15.389	13.045	EPSD	ICGC;COSMIC	14.946	Loss
STE_STE20_PAKB_PAK4_ST	O96013	PAK4	O96013	PAK4	S142	G149V	149	Missense	distal	7	no	15.389	15.334	EPSD	ICGC	14.946	Down-regulation
STE_STE20_PAKB_PAK4_ST	O96013	PAK4	O96013	PAK4	S217	T213M	213	Missense	distal	-4	no	15.691	15.710	EPSD	ICGC	14.946	Up-regulation
STE_STE20_PAKB_PAK4_ST	O96013	PAK4	O96013	PAK4	S246	P250L	250	Missense	distal	4	no	15.674	16.372	EPSD	ICGC	14.946	Up-regulation
STE_STE20_PAKB_PAK4_ST	O96013	PAK4	O96013	PAK4	S247	P250L	250	Missense	distal	3	no	16.474	17.018	EPSD	ICGC	14.946	Up-regulation
STE_STE20_PAKB_PAK4_ST	O96013	PAK4	O96013	PAK4	S474	V476D	476	Missense	proximal	2	no	31.770	31.689	PhosphoSitePlus	ICGC;COSMIC	14.946	Down-regulation
STE_STE20_PAKB_PAK4_ST	O00401	WASL	O96013	PAK4	S62	G63V	63	Missense	proximal	1	no	18.080	18.428	EPSD	ICGC;COSMIC	14.946	Up-regulation
STE_STE20_PAKB_PAK4_ST	O00401	WASL	O96013	PAK4	S207	T205K	205	Missense	proximal	-2	no	9.403	15.205	EPSD	ICGC	14.946	Gain
STE_STE20_PAKB_PAK4_ST	O00401	WASL	O96013	PAK4	S252	T251K	251	Missense	proximal	-1	no	19.101	22.220	EPSD	ICGC	14.946	Up-regulation
STE_STE20_PAKB_PAK4_ST	O00401	WASL	O96013	PAK4	S252	E250K	250	Missense	proximal	-2	no	19.101	23.414	EPSD	ICGC;COSMIC	14.946	Up-regulation
STE_STE20_PAKB_PAK4_ST	O00401	WASL	O96013	PAK4	S479	Q476K	476	Missense	distal	-3	no	18.096	23.604	EPSD	ICGC	14.946	Up-regulation
STE_STE20_PAKB_PAK4_ST	O00401	WASL	O96013	PAK4	S479	S479R	479	Missense	central	0	yes	18.096	0.000	EPSD	ICGC	14.946	Loss
STE_STE20_PAKB_PAK4_ST	O00401	WASL	O96013	PAK4	S479	S479N	479	Missense	central	0	yes	18.096	0.000	EPSD	ICGC;COSMIC	14.946	Loss
STE_STE20_PAKB_PAK4_ST	O00401	WASL	O96013	PAK4	S484	S479R	479	Missense	distal	-5	no	24.018	24.601	PhosphoSitePlus;EPSD	ICGC	14.946	Up-regulation
STE_STE20_PAKB_PAK4_ST	O00401	WASL	O96013	PAK4	S484	S479N	479	Missense	distal	-5	no	24.018	23.937	PhosphoSitePlus;EPSD	ICGC;COSMIC	14.946	Down-regulation
STE_STE20_PAKB_PAK4_ST	O00401	WASL	O96013	PAK4	S485	S479R	479	Missense	distal	-6	no	25.842	25.953	EPSD;PhosphoSitePlus	ICGC	14.946	Up-regulation
STE_STE20_PAKB_PAK4_ST	O00401	WASL	O96013	PAK4	S485	S479N	479	Missense	distal	-6	no	25.842	25.727	EPSD;PhosphoSitePlus	ICGC;COSMIC	14.946	Down-regulation
STE_STE20_PAKB_PAK4_ST	P18084	ITGB5	O96013	PAK4	S149	M150T	150	Missense	proximal	1	no	16.176	15.658	EPSD	ICGC	14.946	Down-regulation
STE_STE20_PAKB_PAK4_ST	P18084	ITGB5	O96013	PAK4	S149	D145E	145	Missense	distal	-4	no	16.176	16.970	EPSD	ICGC	14.946	Up-regulation
STE_STE20_PAKB_PAK4_ST	P18084	ITGB5	O96013	PAK4	S149	L146I	146	Missense	distal	-3	no	16.176	15.934	EPSD	ICGC	14.946	Down-regulation
STE_STE20_PAKB_PAK4_ST	P18084	ITGB5	O96013	PAK4	S149	S147Y	147	Missense	proximal	-2	no	16.176	17.447	EPSD	ICGC;COSMIC	14.946	Up-regulation
STE_STE20_PAKB_PAK4_ST	P18084	ITGB5	O96013	PAK4	S759	R752M	752	Missense	distal	-7	no	26.078	24.000	PhosphoSitePlus;EPSD	ICGC;COSMIC	14.946	Down-regulation
STE_STE20_PAKB_PAK4_ST	P18084	ITGB5	O96013	PAK4	S759	S759R	759	Missense	central	0	yes	26.078	0.000	PhosphoSitePlus;EPSD	ICGC	14.946	Loss
STE_STE20_PAKB_PAK4_ST	P18084	ITGB5	O96013	PAK4	S759	R765H	765	Missense	distal	6	no	26.078	26.376	PhosphoSitePlus;EPSD	ICGC;COSMIC	14.946	Up-regulation
STE_STE20_PAKB_PAK4_ST	P18084	ITGB5	O96013	PAK4	S762	S759R	759	Missense	distal	-3	no	23.858	29.187	EPSD;PhosphoSitePlus	ICGC	14.946	Up-regulation
STE_STE20_PAKB_PAK4_ST	P18084	ITGB5	O96013	PAK4	S762	R765H	765	Missense	distal	3	no	23.858	24.223	EPSD;PhosphoSitePlus	ICGC;COSMIC	14.946	Up-regulation
STE_STE20_PAKB_PAK4_ST	P18084	ITGB5	O96013	PAK4	S770	R775G	775	Missense	distal	5	no	18.652	18.538	EPSD	ICGC;COSMIC	14.946	Down-regulation
STE_STE20_PAKB_PAK4_ST	P18084	ITGB5	O96013	PAK4	S770	P777R	777	Missense	distal	7	no	18.652	18.328	EPSD	ICGC;COSMIC	14.946	Down-regulation
STE_STE20_PAKB_PAK4_ST	P18084	ITGB5	O96013	PAK4	S770	R765H	765	Missense	distal	-5	no	18.652	18.166	EPSD	ICGC;COSMIC	14.946	Down-regulation
STE_STE20_PAKB_PAK4_ST	P18084	ITGB5	O96013	PAK4	S779	P777R	777	Missense	proximal	-2	no	13.502	19.272	EPSD	ICGC;COSMIC	14.946	Gain
STE_STE20_PAKB_PAK4_ST	P49023	PXN	O96013	PAK4	S272	S272L	272	Missense	central	0	yes	23.039	0.000	PhosphoSitePlus	ICGC;COSMIC;CCLE	14.946	Loss
STE_STE20_PAKB_PAK4_ST	P49023	PXN	O96013	PAK4	S320	S322L	322	Missense	proximal	2	no	15.904	13.511	EPSD	ICGC;COSMIC	14.946	Loss
STE_STE20_PAKB_PAK4_ST	P49023	PXN	O96013	PAK4	S533	H526Q	526	Missense	distal	-7	no	18.804	19.274	EPSD	ICGC	14.946	Up-regulation
STE_STE20_PAKB_PAK4_ST	Q92974	ARHGEF2	O96013	PAK4	S107	N102K	102	Missense	distal	-5	no	15.698	16.274	EPSD	ICGC	14.946	Up-regulation
STE_STE20_PAKB_PAK4_ST	Q92974	ARHGEF2	O96013	PAK4	S133	R139S	139	Missense	distal	6	no	16.653	16.969	EPSD	ICGC	14.946	Up-regulation
STE_STE20_PAKB_PAK4_ST	Q92974	ARHGEF2	O96013	PAK4	S142	R139S	139	Missense	distal	-3	no	17.668	12.339	EPSD	ICGC	14.946	Loss
STE_STE20_PAKB_PAK4_ST	Q92974	ARHGEF2	O96013	PAK4	S143	R139S	139	Missense	distal	-4	no	23.198	23.689	EPSD	ICGC	14.946	Up-regulation
STE_STE20_PAKB_PAK4_ST	P04637	TP53	O96013	PAK4	S46	D48G	48	Missense	proximal	2	no	16.273	16.238	EPSD	ICGC;COSMIC	14.946	Down-regulation
STE_STE20_PAKB_PAK4_ST	P04637	TP53	O96013	PAK4	S46	Q52K	52	Missense	distal	6	no	16.273	16.153	EPSD	ICGC	14.946	Down-regulation
STE_STE20_PAKB_PAK4_ST	P04637	TP53	O96013	PAK4	S106	G105A	105	Missense	proximal	-1	no	13.479	15.772	EPSD	ICGC;COSMIC	14.946	Gain
STE_STE20_PAKB_PAK4_ST	P04637	TP53	O96013	PAK4	S127	C124R	124	Missense	distal	-3	no	7.666	15.188	EPSD	ICGC;COSMIC;GDSC;CCLE	14.946	Gain
STE_STE20_PAKB_PAK4_ST	P04637	TP53	O96013	PAK4	S183	C182W	182	Missense	proximal	-1	no	14.982	15.420	EPSD	ICGC;COSMIC	14.946	Up-regulation
STE_STE20_PAKB_PAK4_ST	P04637	TP53	O96013	PAK4	S183	H178D	178	Missense	distal	-5	no	14.982	14.750	EPSD	ICGC;COSMIC;CCLE	14.946	Loss
STE_STE20_PAKB_PAK4_ST	P04637	TP53	O96013	PAK4	S183	D184H	184	Missense	proximal	1	no	14.982	15.579	EPSD	ICGC;COSMIC	14.946	Up-regulation
STE_STE20_PAKB_PAK4_ST	P04637	TP53	O96013	PAK4	S183	A189T	189	Missense	distal	6	no	14.982	15.048	EPSD	ICGC;COSMIC	14.946	Up-regulation
STE_STE20_PAKB_PAK4_ST	P04637	TP53	O96013	PAK4	S183	P190T	190	Missense	distal	7	no	14.982	14.760	EPSD	ICGC;COSMIC	14.946	Loss
STE_STE20_PAKB_PAK4_ST	P04637	TP53	O96013	PAK4	S183	P190S	190	Missense	distal	7	no	14.982	14.676	EPSD	ICGC;COSMIC	14.946	Loss
STE_STE20_PAKB_PAK4_ST	P04637	TP53	O96013	PAK4	S183	A189D	189	Missense	distal	6	no	14.982	15.077	EPSD	ICGC;COSMIC	14.946	Up-regulation
STE_STE20_PAKB_PAK4_ST	P04637	TP53	O96013	PAK4	S183	E180D	180	Missense	distal	-3	no	14.982	15.363	EPSD	ICGC;COSMIC	14.946	Up-regulation
STE_STE20_PAKB_PAK4_ST	P04637	TP53	O96013	PAK4	S183	C176G	176	Missense	distal	-7	no	14.982	17.107	EPSD	ICGC;COSMIC	14.946	Up-regulation
STE_STE20_PAKB_PAK4_ST	P04637	TP53	O96013	PAK4	S215	P219T	219	Missense	distal	4	no	24.434	24.558	PhosphoSitePlus	ICGC;COSMIC	14.946	Up-regulation
STE_STE20_PAKB_PAK4_ST	P04637	TP53	O96013	PAK4	S215	H214D	214	Missense	proximal	-1	no	24.434	23.183	PhosphoSitePlus	ICGC;COSMIC	14.946	Down-regulation
STE_STE20_PAKB_PAK4_ST	P04637	TP53	O96013	PAK4	S215	Y220N	220	Missense	distal	5	no	24.434	24.458	PhosphoSitePlus	ICGC;COSMIC	14.946	Up-regulation
STE_STE20_PAKB_PAK4_ST	P04637	TP53	O96013	PAK4	S215	E221V	221	Missense	distal	6	no	24.434	24.455	PhosphoSitePlus	ICGC;COSMIC	14.946	Up-regulation
STE_STE20_PAKB_PAK4_ST	P04637	TP53	O96013	PAK4	S215	E221K	221	Missense	distal	6	no	24.434	24.236	PhosphoSitePlus	ICGC;COSMIC	14.946	Down-regulation
STE_STE20_PAKB_PAK4_ST	P04637	TP53	O96013	PAK4	S215	H214Y	214	Missense	proximal	-1	no	24.434	24.115	PhosphoSitePlus	ICGC;COSMIC	14.946	Down-regulation
STE_STE20_PAKB_PAK4_ST	P04637	TP53	O96013	PAK4	S215	T211P	211	Missense	distal	-4	no	24.434	25.038	PhosphoSitePlus	ICGC;COSMIC	14.946	Up-regulation
STE_STE20_PAKB_PAK4_ST	P04637	TP53	O96013	PAK4	S215	F212V	212	Missense	distal	-3	no	24.434	19.649	PhosphoSitePlus	ICGC;COSMIC	14.946	Down-regulation
STE_STE20_PAKB_PAK4_ST	P04637	TP53	O96013	PAK4	S215	D208V	208	Missense	distal	-7	no	24.434	22.483	PhosphoSitePlus	ICGC;COSMIC	14.946	Down-regulation
STE_STE20_PAKB_PAK4_ST	P04637	TP53	O96013	PAK4	S215	V217G	217	Missense	proximal	2	no	24.434	24.319	PhosphoSitePlus	ICGC;COSMIC;CCLE	14.946	Down-regulation
STE_STE20_PAKB_PAK4_ST	P04637	TP53	O96013	PAK4	S371	T377P	377	Missense	distal	6	no	21.189	21.306	EPSD	ICGC;COSMIC	14.946	Up-regulation
STE_STE20_PAKB_PAK4_ST	P04637	TP53	O96013	PAK4	S371	G374C	374	Missense	distal	3	no	21.189	21.316	EPSD	ICGC;COSMIC	14.946	Up-regulation
STE_STE20_PAKB_PAK4_ST	P04637	TP53	O96013	PAK4	S376	T377P	377	Missense	proximal	1	no	18.237	16.324	EPSD	ICGC;COSMIC	14.946	Down-regulation
STE_STE20_PAKB_PAK4_ST	P04637	TP53	O96013	PAK4	S376	G374C	374	Missense	proximal	-2	no	18.237	17.137	EPSD	ICGC;COSMIC	14.946	Down-regulation
STE_STE20_PAKB_PAK4_ST	P04637	TP53	O96013	PAK4	S376	R379S	379	Missense	distal	3	no	18.237	18.027	EPSD	ICGC	14.946	Down-regulation
STE_STE20_PAKB_PAK4_ST	P04637	TP53	O96013	PAK4	S376	R379C	379	Missense	distal	3	no	18.237	18.936	EPSD	ICGC;COSMIC	14.946	Up-regulation
STE_STE20_PAKB_PAK4_ST	P04637	TP53	O96013	PAK4	S378	T377P	377	Missense	proximal	-1	no	15.211	14.872	EPSD	ICGC;COSMIC	14.946	Loss
STE_STE20_PAKB_PAK4_ST	P04637	TP53	O96013	PAK4	S378	F385L	385	Missense	distal	7	no	15.211	15.309	EPSD	ICGC;COSMIC	14.946	Up-regulation
STE_STE20_PAKB_PAK4_ST	P04637	TP53	O96013	PAK4	S378	G374C	374	Missense	distal	-4	no	15.211	14.003	EPSD	ICGC;COSMIC	14.946	Loss
STE_STE20_PAKB_PAK4_ST	P04637	TP53	O96013	PAK4	S378	R379S	379	Missense	proximal	1	no	15.211	14.642	EPSD	ICGC	14.946	Loss
STE_STE20_PAKB_PAK4_ST	P04637	TP53	O96013	PAK4	S378	R379C	379	Missense	proximal	1	no	15.211	14.711	EPSD	ICGC;COSMIC	14.946	Loss
STE_STE20_PAKB_PAK4_ST	P53667	LIMK1	O96013	PAK4	S296	R295Q	295	Missense	proximal	-1	no	17.236	13.895	EPSD	ICGC;COSMIC	14.946	Loss
STE_STE20_PAKB_PAK4_ST	P53667	LIMK1	O96013	PAK4	S302	R295Q	295	Missense	distal	-7	no	16.285	13.941	EPSD	ICGC;COSMIC	14.946	Loss
STE_STE20_PAKB_PAK4_ST	P53667	LIMK1	O96013	PAK4	S321	R325C	325	Missense	distal	4	no	16.722	17.056	EPSD	ICGC;COSMIC	14.946	Up-regulation
STE_STE20_PAKB_PAK4_ST	P53667	LIMK1	O96013	PAK4	S323	R325C	325	Missense	proximal	2	no	21.679	21.710	EPSD	ICGC;COSMIC	14.946	Up-regulation
STE_STE20_PAKB_PAK4_ST	P03372	ESR1	O96013	PAK4	S10	H16R	16	Missense	distal	6	no	15.151	14.854	EPSD	ICGC	14.946	Loss
STE_STE20_PAKB_PAK4_ST	P03372	ESR1	O96013	PAK4	S167	E163Q	163	Missense	distal	-4	no	19.706	19.107	EPSD	ICGC;COSMIC	14.946	Down-regulation
STE_STE20_PAKB_PAK4_ST	P03372	ESR1	O96013	PAK4	S212	C205Y	205	Missense	distal	-7	no	16.546	18.086	EPSD	ICGC;COSMIC	14.946	Up-regulation
STE_STE20_PAKB_PAK4_ST	P03372	ESR1	O96013	PAK4	S236	Q238R	238	Missense	proximal	2	no	17.263	16.597	EPSD	ICGC	14.946	Down-regulation
STE_STE20_PAKB_PAK4_ST	P03372	ESR1	O96013	PAK4	S236	L242I	242	Missense	distal	6	no	17.263	17.164	EPSD	ICGC	14.946	Down-regulation
STE_STE20_PAKB_PAK4_ST	P03372	ESR1	O96013	PAK4	S236	R233M	233	Missense	distal	-3	no	17.263	14.593	EPSD	ICGC;COSMIC	14.946	Loss
STE_STE20_PAKB_PAK4_ST	P03372	ESR1	O96013	PAK4	S305	K302T	302	Missense	distal	-3	no	28.139	21.014	PhosphoSitePlus	ICGC;COSMIC	14.946	Down-regulation
STE_STE20_PAKB_PAK4_ST	P03372	ESR1	O96013	PAK4	S305	R300L	300	Missense	distal	-5	no	28.139	27.146	PhosphoSitePlus	ICGC;COSMIC	14.946	Down-regulation
STE_STE20_PAKB_PAK4_ST	P03372	ESR1	O96013	PAK4	S305	R300S	300	Missense	distal	-5	no	28.139	27.556	PhosphoSitePlus	ICGC;COSMIC	14.946	Down-regulation
STE_STE20_PAKB_PAK4_ST	P03372	ESR1	O96013	PAK4	S305	R300H	300	Missense	distal	-5	no	28.139	27.652	PhosphoSitePlus	ICGC;COSMIC	14.946	Down-regulation
STE_STE20_PAKB_PAK4_ST	P03372	ESR1	O96013	PAK4	S576	S576L	576	Missense	central	0	yes	16.807	0.000	EPSD	ICGC;COSMIC	14.946	Loss
STE_STE20_PAKB_PAK4_ST	Q93045	STMN2	O96013	PAK4	S16	K9N	9	Missense	distal	-7	no	15.340	11.716	EPSD	ICGC;COSMIC	14.946	Loss
STE_STE20_PAKB_PAK4_ST	Q93045	STMN2	O96013	PAK4	S16	E10K	10	Missense	distal	-6	no	15.340	15.525	EPSD	ICGC;COSMIC	14.946	Up-regulation
STE_STE20_PAKB_PAK4_ST	Q93045	STMN2	O96013	PAK4	S50	Q52H	52	Missense	proximal	2	no	25.990	25.577	PhosphoSitePlus	ICGC;COSMIC	14.946	Down-regulation
STE_STE20_PAKB_PAK4_ST	Q93045	STMN2	O96013	PAK4	S50	A53S	53	Missense	distal	3	no	25.990	25.132	PhosphoSitePlus	ICGC;COSMIC	14.946	Down-regulation
STE_STE20_PAKB_PAK4_ST	Q93045	STMN2	O96013	PAK4	S50	K43M	43	Missense	distal	-7	no	25.990	23.912	PhosphoSitePlus	ICGC;COSMIC	14.946	Down-regulation
STE_STE20_PAKB_PAK4_ST	Q93045	STMN2	O96013	PAK4	S50	E55K	55	Missense	distal	5	no	25.990	26.090	PhosphoSitePlus	ICGC	14.946	Up-regulation
STE_STE20_PAKB_PAK4_ST	Q93045	STMN2	O96013	PAK4	S50	A49T	49	Missense	proximal	-1	no	25.990	23.573	PhosphoSitePlus	ICGC;COSMIC	14.946	Down-regulation
STE_STE20_PAKB_PAK4_ST	Q93045	STMN2	O96013	PAK4	S80	S73F	73	Missense	distal	-7	no	15.305	14.407	EPSD	ICGC	14.946	Loss
STE_STE20_PAKB_PAK4_ST	Q93045	STMN2	O96013	PAK4	S97	E92V	92	Missense	distal	-5	no	24.764	24.328	EPSD	ICGC;COSMIC	14.946	Down-regulation
STE_STE20_PAKB_PAK4_ST	Q93045	STMN2	O96013	PAK4	S97	A90D	90	Missense	distal	-7	no	24.764	24.162	EPSD	ICGC;COSMIC	14.946	Down-regulation
CAMK_MLCK_MYLK2_ST	Q06413	MEF2C	Q9H1R3	MYLK2	T70	T70M	70	Missense	central	0	yes	3.520	0.000	EPSD	ICGC;COSMIC;CCLE	3.166	Loss
CAMK_MLCK_MYLK2_ST	Q06413	MEF2C	Q9H1R3	MYLK2	T70	H76N	76	Missense	distal	6	no	3.520	3.587	EPSD	ICGC;COSMIC	3.166	Up-regulation
CAMK_MLCK_MYLK2_ST	Q06413	MEF2C	Q9H1R3	MYLK2	T70	L66I	66	Missense	distal	-4	no	3.520	3.398	EPSD	ICGC;COSMIC	3.166	Down-regulation
CAMK_MLCK_MYLK2_ST	Q06413	MEF2C	Q9H1R3	MYLK2	T70	T70K	70	Missense	central	0	yes	3.520	0.000	EPSD	ICGC	3.166	Loss
CAMK_MLCK_MYLK2_ST	Q06413	MEF2C	Q9H1R3	MYLK2	T70	D63E	63	Missense	distal	-7	no	3.520	3.499	EPSD	ICGC;COSMIC	3.166	Down-regulation
CAMK_MLCK_MYLK2_ST	Q06413	MEF2C	Q9H1R3	MYLK2	T70	Y69N	69	Missense	proximal	-1	no	3.520	3.544	EPSD	ICGC;COSMIC	3.166	Up-regulation
CAMK_MLCK_MYLK2_ST	Q06413	MEF2C	Q9H1R3	MYLK2	T70	Y69H	69	Missense	proximal	-1	no	3.520	3.534	EPSD	ICGC;COSMIC;GDSC;CCLE	3.166	Up-regulation
CAMK_MLCK_MYLK2_ST	Q06413	MEF2C	Q9H1R3	MYLK2	T70	E77V	77	Missense	distal	7	no	3.520	3.539	EPSD	ICGC;COSMIC	3.166	Up-regulation
CAMK_MLCK_MYLK2_ST	Q06413	MEF2C	Q9H1R3	MYLK2	T80	E86K	86	Missense	distal	6	no	7.263	7.009	PhosphoSitePlus	ICGC;COSMIC	3.166	Down-regulation
CAMK_MLCK_MYLK2_ST	Q06413	MEF2C	Q9H1R3	MYLK2	T80	V85E	85	Missense	distal	5	no	7.263	7.113	PhosphoSitePlus	ICGC;COSMIC	3.166	Down-regulation
CAMK_MLCK_MYLK2_ST	Q06413	MEF2C	Q9H1R3	MYLK2	T80	H76N	76	Missense	distal	-4	no	7.263	7.179	PhosphoSitePlus	ICGC;COSMIC	3.166	Down-regulation
CAMK_MLCK_MYLK2_ST	Q06413	MEF2C	Q9H1R3	MYLK2	T80	T80K	80	Missense	central	0	yes	7.263	0.000	PhosphoSitePlus	ICGC	3.166	Loss
CAMK_MLCK_MYLK2_ST	Q06413	MEF2C	Q9H1R3	MYLK2	T80	D83V	83	Missense	distal	3	no	7.263	7.267	PhosphoSitePlus	ICGC	3.166	Up-regulation
CAMK_MLCK_MYLK2_ST	Q06413	MEF2C	Q9H1R3	MYLK2	T80	E77V	77	Missense	distal	-3	no	7.263	7.024	PhosphoSitePlus	ICGC;COSMIC	3.166	Down-regulation
CAMK_MLCK_MYLK2_ST	Q06413	MEF2C	Q9H1R3	MYLK2	S396	P397R	397	Missense	proximal	1	no	3.137	3.498	EPSD	ICGC;COSMIC	3.166	Gain
CAMK_MLCK_MYLK2_ST	Q06413	MEF2C	Q9H1R3	MYLK2	S396	P397T	397	Missense	proximal	1	no	3.137	3.324	EPSD	ICGC;COSMIC	3.166	Gain
CAMK_RAD53_CHEK2_ST	P04637	TP53	O96017	CHEK2	S15	E11K	11	Missense	distal	-4	no	10.671	11.808	EPSD;PhosphoSitePlus	ICGC;COSMIC	8.561	Up-regulation
CAMK_RAD53_CHEK2_ST	P04637	TP53	O96017	CHEK2	S37	P34L	34	Missense	distal	-3	no	10.326	8.441	EPSD;PhosphoSitePlus	ICGC;COSMIC	8.561	Loss
CAMK_RAD53_CHEK2_ST	P04637	TP53	O96017	CHEK2	S37	S33F	33	Missense	distal	-4	no	10.326	7.445	EPSD;PhosphoSitePlus	ICGC;COSMIC	8.561	Loss
CAMK_RAD53_CHEK2_ST	P04637	TP53	O96017	CHEK2	S37	N30I	30	Missense	distal	-7	no	10.326	9.241	EPSD;PhosphoSitePlus	ICGC	8.561	Down-regulation
CAMK_RAD53_CHEK2_ST	P04637	TP53	O96017	CHEK2	T81	A88D	88	Missense	distal	7	no	9.581	9.599	EPSD	ICGC	8.561	Up-regulation
CAMK_RAD53_CHEK2_ST	P04637	TP53	O96017	CHEK2	T81	P87Q	87	Missense	distal	6	no	9.581	9.342	EPSD	ICGC;COSMIC	8.561	Down-regulation
CAMK_RAD53_CHEK2_ST	P04637	TP53	O96017	CHEK2	S99	Q100K	100	Missense	proximal	1	no	8.743	5.562	EPSD	ICGC;COSMIC	8.561	Loss
CAMK_RAD53_CHEK2_ST	P04637	TP53	O96017	CHEK2	S99	P92T	92	Missense	distal	-7	no	8.743	8.131	EPSD	ICGC;COSMIC	8.561	Loss
CAMK_RAD53_CHEK2_ST	P04637	TP53	O96017	CHEK2	S99	P92H	92	Missense	distal	-7	no	8.743	8.941	EPSD	ICGC;COSMIC	8.561	Up-regulation
CAMK_RAD53_CHEK2_ST	P04637	TP53	O96017	CHEK2	S99	G105A	105	Missense	distal	6	no	8.743	8.830	EPSD	ICGC;COSMIC	8.561	Up-regulation
CAMK_RAD53_CHEK2_ST	P04637	TP53	O96017	CHEK2	S127	C124R	124	Missense	distal	-3	no	-0.061	10.861	EPSD	ICGC;COSMIC;GDSC;CCLE	8.561	Gain
CAMK_RAD53_CHEK2_ST	P04637	TP53	O96017	CHEK2	T155	R156L	156	Missense	proximal	1	no	6.638	8.996	EPSD	ICGC;COSMIC	8.561	Gain
CAMK_RAD53_CHEK2_ST	P04637	TP53	O96017	CHEK2	T155	P152R	152	Missense	distal	-3	no	6.638	12.364	EPSD	ICGC;COSMIC	8.561	Gain
CAMK_RAD53_CHEK2_ST	P04637	TP53	O96017	CHEK2	S269	A276V	276	Missense	distal	7	no	12.111	12.118	EPSD	ICGC;COSMIC	8.561	Up-regulation
CAMK_RAD53_CHEK2_ST	P04637	TP53	O96017	CHEK2	S269	V274A	274	Missense	distal	5	no	12.111	12.239	EPSD	ICGC;COSMIC	8.561	Up-regulation
CAMK_RAD53_CHEK2_ST	P04637	TP53	O96017	CHEK2	S269	V272E	272	Missense	distal	3	no	12.111	11.820	EPSD	ICGC;COSMIC;CCLE	8.561	Down-regulation
CAMK_RAD53_CHEK2_ST	P04637	TP53	O96017	CHEK2	S269	L265T	265	Missense	distal	-4	no	12.111	12.657	EPSD	ICGC	8.561	Up-regulation
CAMK_RAD53_CHEK2_ST	P04637	TP53	O96017	CHEK2	S269	N268I	268	Missense	proximal	-1	no	12.111	12.115	EPSD	ICGC;COSMIC;GDSC;CCLE	8.561	Up-regulation
CAMK_RAD53_CHEK2_ST	P04637	TP53	O96017	CHEK2	S269	E271D	271	Missense	proximal	2	no	12.111	11.919	EPSD	ICGC;COSMIC	8.561	Down-regulation
CAMK_RAD53_CHEK2_ST	P04637	TP53	O96017	CHEK2	S371	T377P	377	Missense	distal	6	no	9.892	9.964	EPSD	ICGC;COSMIC	8.561	Up-regulation
CAMK_RAD53_CHEK2_ST	P04637	TP53	O96017	CHEK2	S371	G374C	374	Missense	distal	3	no	9.892	9.387	EPSD	ICGC;COSMIC	8.561	Down-regulation
CAMK_RAD53_CHEK2_ST	O00716	E2F3	O96017	CHEK2	S124	G125S	125	Missense	proximal	1	no	13.499	13.329	PhosphoSitePlus	ICGC;COSMIC	8.561	Down-regulation
CAMK_RAD53_CHEK2_ST	O00716	E2F3	O96017	CHEK2	T181	G184C	184	Missense	distal	3	no	10.130	9.625	EPSD	ICGC;COSMIC;CCLE	8.561	Down-regulation
CAMK_RAD53_CHEK2_ST	O00716	E2F3	O96017	CHEK2	T181	R178L	178	Missense	distal	-3	no	10.130	2.518	EPSD	ICGC	8.561	Loss
CAMK_RAD53_CHEK2_ST	O00716	E2F3	O96017	CHEK2	S308	D303H	303	Missense	distal	-5	no	10.470	11.182	EPSD	ICGC;COSMIC	8.561	Up-regulation
CAMK_RAD53_CHEK2_ST	O43255	SIAH2	O96017	CHEK2	T119	T113K	113	Missense	distal	-6	no	10.063	10.127	EPSD;PhosphoSitePlus	ICGC	8.561	Up-regulation
CAMK_RAD53_CHEK2_ST	O43255	SIAH2	O96017	CHEK2	T119	L118M	118	Missense	proximal	-1	no	10.063	10.307	EPSD;PhosphoSitePlus	ICGC;COSMIC	8.561	Up-regulation
CAMK_RAD53_CHEK2_ST	O43255	SIAH2	O96017	CHEK2	T119	I122T	122	Missense	distal	3	no	10.063	9.477	EPSD;PhosphoSitePlus	ICGC	8.561	Down-regulation
CAMK_RAD53_CHEK2_ST	O43255	SIAH2	O96017	CHEK2	T119	A126D	126	Missense	distal	7	no	10.063	10.081	EPSD;PhosphoSitePlus	ICGC;COSMIC	8.561	Up-regulation
CAMK_RAD53_CHEK2_ST	O96017	CHEK2	O96017	CHEK2	S33	G37C	37	Missense	distal	4	no	10.156	9.919	PhosphoSitePlus;EPSD	ICGC;COSMIC	8.561	Down-regulation
CAMK_RAD53_CHEK2_ST	O96017	CHEK2	O96017	CHEK2	S35	G37C	37	Missense	proximal	2	no	10.340	10.182	EPSD;PhosphoSitePlus	ICGC;COSMIC	8.561	Down-regulation
CAMK_RAD53_CHEK2_ST	O96017	CHEK2	O96017	CHEK2	S44	G37C	37	Missense	distal	-7	no	8.832	8.083	EPSD	ICGC;COSMIC	8.561	Loss
CAMK_RAD53_CHEK2_ST	O96017	CHEK2	O96017	CHEK2	S44	M46I	46	Missense	proximal	2	no	8.832	8.827	EPSD	ICGC;COSMIC	8.561	Down-regulation
CAMK_RAD53_CHEK2_ST	O96017	CHEK2	O96017	CHEK2	S44	S49F	49	Missense	distal	5	no	8.832	8.443	EPSD	ICGC;COSMIC	8.561	Loss
CAMK_RAD53_CHEK2_ST	O96017	CHEK2	O96017	CHEK2	S44	T45M	45	Missense	proximal	1	no	8.832	9.448	EPSD	ICGC;COSMIC	8.561	Up-regulation
CAMK_RAD53_CHEK2_ST	O96017	CHEK2	O96017	CHEK2	S50	M46I	46	Missense	distal	-4	no	9.393	9.104	EPSD	ICGC;COSMIC	8.561	Down-regulation
CAMK_RAD53_CHEK2_ST	O96017	CHEK2	O96017	CHEK2	S50	S49F	49	Missense	proximal	-1	no	9.393	9.793	EPSD	ICGC;COSMIC	8.561	Up-regulation
CAMK_RAD53_CHEK2_ST	O96017	CHEK2	O96017	CHEK2	S50	T45M	45	Missense	distal	-5	no	9.393	8.823	EPSD	ICGC;COSMIC	8.561	Down-regulation
CAMK_RAD53_CHEK2_ST	O96017	CHEK2	O96017	CHEK2	S120	C121S	121	Missense	proximal	1	no	8.749	6.996	EPSD;PhosphoSitePlus	ICGC;COSMIC	8.561	Loss
CAMK_RAD53_CHEK2_ST	O96017	CHEK2	O96017	CHEK2	S140	R145W	145	Missense	distal	5	no	11.986	11.517	EPSD;PhosphoSitePlus	ICGC;COSMIC;CCLE	8.561	Down-regulation
CAMK_RAD53_CHEK2_ST	O96017	CHEK2	O96017	CHEK2	S140	R145Q	145	Missense	distal	5	no	11.986	11.891	EPSD;PhosphoSitePlus	ICGC;COSMIC	8.561	Down-regulation
CAMK_RAD53_CHEK2_ST	O96017	CHEK2	O96017	CHEK2	S140	H143N	143	Missense	distal	3	no	11.986	12.232	EPSD;PhosphoSitePlus	ICGC;COSMIC	8.561	Up-regulation
CAMK_RAD53_CHEK2_ST	O96017	CHEK2	O96017	CHEK2	S140	T138A	138	Missense	proximal	-2	no	11.986	12.131	EPSD;PhosphoSitePlus	ICGC;COSMIC	8.561	Up-regulation
CAMK_RAD53_CHEK2_ST	O96017	CHEK2	O96017	CHEK2	S140	H143Q	143	Missense	distal	3	no	11.986	11.187	EPSD;PhosphoSitePlus	ICGC;COSMIC	8.561	Down-regulation
CAMK_RAD53_CHEK2_ST	O96017	CHEK2	O96017	CHEK2	S140	D134Y	134	Missense	distal	-6	no	11.986	11.949	EPSD;PhosphoSitePlus	ICGC;COSMIC	8.561	Down-regulation
CAMK_RAD53_CHEK2_ST	O96017	CHEK2	O96017	CHEK2	S140	K135T	135	Missense	distal	-5	no	11.986	12.692	EPSD;PhosphoSitePlus	ICGC;COSMIC	8.561	Up-regulation
CAMK_RAD53_CHEK2_ST	O96017	CHEK2	O96017	CHEK2	T383	Y390N	390	Missense	distal	7	no	10.620	10.599	EPSD;PhosphoSitePlus	ICGC;COSMIC	8.561	Down-regulation
CAMK_RAD53_CHEK2_ST	O96017	CHEK2	O96017	CHEK2	T383	E377K	377	Missense	distal	-6	no	10.620	10.722	EPSD;PhosphoSitePlus	ICGC;COSMIC	8.561	Up-regulation
CAMK_RAD53_CHEK2_ST	O96017	CHEK2	O96017	CHEK2	T383	S379F	379	Missense	distal	-4	no	10.620	7.739	EPSD;PhosphoSitePlus	ICGC;COSMIC	8.561	Loss
CAMK_RAD53_CHEK2_ST	O96017	CHEK2	O96017	CHEK2	T383	L380V	380	Missense	distal	-3	no	10.620	8.786	EPSD;PhosphoSitePlus	ICGC;COSMIC	8.561	Down-regulation
CAMK_RAD53_CHEK2_ST	O96017	CHEK2	O96017	CHEK2	T383	G386V	386	Missense	distal	3	no	10.620	10.574	EPSD;PhosphoSitePlus	ICGC;COSMIC	8.561	Down-regulation
CAMK_RAD53_CHEK2_ST	O96017	CHEK2	O96017	CHEK2	T383	T378A	378	Missense	distal	-5	no	10.620	10.105	EPSD;PhosphoSitePlus	ICGC	8.561	Down-regulation
CAMK_RAD53_CHEK2_ST	O96017	CHEK2	O96017	CHEK2	T387	L391F	391	Missense	distal	4	no	8.388	9.060	EPSD;PhosphoSitePlus	ICGC;COSMIC	8.561	Gain
CAMK_RAD53_CHEK2_ST	O96017	CHEK2	O96017	CHEK2	T389	Y390N	390	Missense	proximal	1	no	9.292	7.348	EPSD	ICGC;COSMIC	8.561	Loss
CAMK_RAD53_CHEK2_ST	O96017	CHEK2	O96017	CHEK2	T389	L396V	396	Missense	distal	7	no	9.292	9.287	EPSD	ICGC;COSMIC	8.561	Down-regulation
CAMK_RAD53_CHEK2_ST	O96017	CHEK2	O96017	CHEK2	T389	A392V	392	Missense	distal	3	no	9.292	9.956	EPSD	ICGC;COSMIC	8.561	Up-regulation
CAMK_RAD53_CHEK2_ST	O96017	CHEK2	O96017	CHEK2	T389	G386V	386	Missense	distal	-3	no	9.292	5.753	EPSD	ICGC;COSMIC	8.561	Loss
CAMK_RAD53_CHEK2_ST	O96017	CHEK2	O96017	CHEK2	T389	L391F	391	Missense	proximal	2	no	9.292	8.797	EPSD	ICGC;COSMIC	8.561	Down-regulation
CAMK_RAD53_CHEK2_ST	O96017	CHEK2	O96017	CHEK2	T432	Q433E	433	Missense	proximal	1	no	8.836	4.314	EPSD;PhosphoSitePlus	ICGC;COSMIC	8.561	Loss
CAMK_RAD53_CHEK2_ST	O96017	CHEK2	O96017	CHEK2	T432	S428F	428	Missense	distal	-4	no	8.836	5.955	EPSD;PhosphoSitePlus	ICGC;COSMIC	8.561	Loss
CAMK_RAD53_CHEK2_ST	O96017	CHEK2	O96017	CHEK2	T432	H430Y	430	Missense	proximal	-2	no	8.836	7.764	EPSD;PhosphoSitePlus	ICGC;COSMIC	8.561	Loss
CAMK_RAD53_CHEK2_ST	O96017	CHEK2	O96017	CHEK2	S435	Q433E	433	Missense	proximal	-2	no	10.217	9.875	EPSD;PhosphoSitePlus	ICGC;COSMIC	8.561	Down-regulation
CAMK_RAD53_CHEK2_ST	O96017	CHEK2	O96017	CHEK2	S435	S428F	428	Missense	distal	-7	no	10.217	6.823	EPSD;PhosphoSitePlus	ICGC;COSMIC	8.561	Loss
CAMK_RAD53_CHEK2_ST	O96017	CHEK2	O96017	CHEK2	S435	H430Y	430	Missense	distal	-5	no	10.217	9.678	EPSD;PhosphoSitePlus	ICGC;COSMIC	8.561	Down-regulation
CAMK_RAD53_CHEK2_ST	O96017	CHEK2	O96017	CHEK2	S516	R521W	521	Missense	distal	5	no	9.518	9.049	EPSD;PhosphoSitePlus	ICGC;COSMIC	8.561	Down-regulation
CAMK_RAD53_CHEK2_ST	O96017	CHEK2	O96017	CHEK2	S516	P509S	509	Missense	distal	-7	no	9.518	9.754	EPSD;PhosphoSitePlus	ICGC;COSMIC	8.561	Up-regulation
CAMK_RAD53_CHEK2_ST	O96017	CHEK2	O96017	CHEK2	S516	R523L	523	Missense	distal	7	no	9.518	9.539	EPSD;PhosphoSitePlus	ICGC;COSMIC	8.561	Up-regulation
CAMK_RAD53_CHEK2_ST	P33981	TTK	O96017	CHEK2	S214	A211S	211	Missense	distal	-3	no	11.199	10.056	EPSD	ICGC	8.561	Down-regulation
CAMK_RAD53_CHEK2_ST	P33981	TTK	O96017	CHEK2	S214	A211D	211	Missense	distal	-3	no	11.199	7.674	EPSD	ICGC;COSMIC	8.561	Loss
CAMK_RAD53_CHEK2_ST	P33981	TTK	O96017	CHEK2	T831	G838S	838	Missense	distal	7	no	10.742	10.729	EPSD	ICGC;COSMIC	8.561	Down-regulation
CAMK_RAD53_CHEK2_ST	P33981	TTK	O96017	CHEK2	S845	G838S	838	Missense	distal	-7	no	8.522	8.994	EPSD	ICGC;COSMIC	8.561	Gain
CAMK_RAD53_CHEK2_ST	Q9NY61	AATF	O96017	CHEK2	S20	E21A	21	Missense	proximal	1	no	7.750	9.808	EPSD	ICGC	8.561	Gain
CAMK_RAD53_CHEK2_ST	Q9NY61	AATF	O96017	CHEK2	S61	D66N	66	Missense	distal	5	no	9.536	9.632	EPSD	ICGC	8.561	Up-regulation
CAMK_RAD53_CHEK2_ST	Q9NY61	AATF	O96017	CHEK2	S141	P147L	147	Missense	distal	6	no	9.381	9.234	EPSD	ICGC	8.561	Down-regulation
CAMK_RAD53_CHEK2_ST	Q9NY61	AATF	O96017	CHEK2	S141	K138E	138	Missense	distal	-3	no	9.381	6.554	EPSD	ICGC	8.561	Loss
CAMK_RAD53_CHEK2_ST	Q9NY61	AATF	O96017	CHEK2	S143	P147L	147	Missense	distal	4	no	13.197	13.289	EPSD;PhosphoSitePlus	ICGC	8.561	Up-regulation
CAMK_RAD53_CHEK2_ST	Q9NY61	AATF	O96017	CHEK2	S143	K138E	138	Missense	distal	-5	no	13.197	13.022	EPSD;PhosphoSitePlus	ICGC	8.561	Down-regulation
CAMK_RAD53_CHEK2_ST	Q9NY61	AATF	O96017	CHEK2	T412	R414C	414	Missense	proximal	2	no	12.808	12.570	EPSD	ICGC	8.561	Down-regulation
CAMK_RAD53_CHEK2_ST	Q9NY61	AATF	O96017	CHEK2	S510	K503R	503	Missense	distal	-7	no	11.310	11.578	PhosphoSitePlus;EPSD	ICGC	8.561	Up-regulation
CAMK_RAD53_CHEK2_ST	Q9NY61	AATF	O96017	CHEK2	S510	K504N	504	Missense	distal	-6	no	11.310	11.081	PhosphoSitePlus;EPSD	ICGC	8.561	Down-regulation
CAMK_RAD53_CHEK2_ST	Q9NY61	AATF	O96017	CHEK2	S510	R507K	507	Missense	distal	-3	no	11.310	6.226	PhosphoSitePlus;EPSD	ICGC	8.561	Loss
CAMK_RAD53_CHEK2_ST	Q9NY61	AATF	O96017	CHEK2	S510	R507M	507	Missense	distal	-3	no	11.310	4.110	PhosphoSitePlus;EPSD	ICGC	8.561	Loss
CAMK_RAD53_CHEK2_ST	Q08050	FOXM1	O96017	CHEK2	S192	R198C	198	Missense	distal	6	no	8.816	8.611	EPSD	ICGC;COSMIC	8.561	Down-regulation
CAMK_RAD53_CHEK2_ST	Q08050	FOXM1	O96017	CHEK2	S284	W281R	281	Missense	distal	-3	no	-3.783	9.446	EPSD	ICGC;COSMIC	8.561	Gain
CAMK_RAD53_CHEK2_ST	Q08050	FOXM1	O96017	CHEK2	S306	T299M	299	Missense	distal	-7	no	8.861	8.160	EPSD	ICGC;COSMIC	8.561	Loss
CAMK_RAD53_CHEK2_ST	Q08050	FOXM1	O96017	CHEK2	S306	W308L	308	Missense	proximal	2	no	8.861	9.189	EPSD	ICGC;COSMIC	8.561	Up-regulation
CAMK_RAD53_CHEK2_ST	Q08050	FOXM1	O96017	CHEK2	T319	R316S	316	Missense	distal	-3	no	10.462	3.605	EPSD	ICGC	8.561	Loss
CAMK_RAD53_CHEK2_ST	Q08050	FOXM1	O96017	CHEK2	S340	P335T	335	Missense	distal	-5	no	9.446	9.302	EPSD	ICGC	8.561	Down-regulation
CAMK_RAD53_CHEK2_ST	Q08050	FOXM1	O96017	CHEK2	S340	P345Q	345	Missense	distal	5	no	9.446	9.543	EPSD	ICGC	8.561	Up-regulation
CAMK_RAD53_CHEK2_ST	Q08050	FOXM1	O96017	CHEK2	S340	P335S	335	Missense	distal	-5	no	9.446	8.886	EPSD	ICGC	8.561	Down-regulation
CAMK_RAD53_CHEK2_ST	Q08050	FOXM1	O96017	CHEK2	T354	I355M	355	Missense	proximal	1	no	15.248	16.846	EPSD	ICGC;COSMIC	8.561	Up-regulation
CAMK_RAD53_CHEK2_ST	Q08050	FOXM1	O96017	CHEK2	T354	I355T	355	Missense	proximal	1	no	15.248	16.230	EPSD	ICGC;COSMIC	8.561	Up-regulation
CAMK_RAD53_CHEK2_ST	Q08050	FOXM1	O96017	CHEK2	T354	L359I	359	Missense	distal	5	no	15.248	15.254	EPSD	ICGC;COSMIC	8.561	Up-regulation
CAMK_RAD53_CHEK2_ST	Q08050	FOXM1	O96017	CHEK2	T354	N352K	352	Missense	proximal	-2	no	15.248	15.647	EPSD	ICGC	8.561	Up-regulation
CAMK_RAD53_CHEK2_ST	Q08050	FOXM1	O96017	CHEK2	T354	R351L	351	Missense	distal	-3	no	15.248	7.637	EPSD	ICGC;COSMIC	8.561	Loss
CAMK_RAD53_CHEK2_ST	Q08050	FOXM1	O96017	CHEK2	T354	R350C	350	Missense	distal	-4	no	15.248	14.243	EPSD	ICGC;COSMIC	8.561	Down-regulation
CAMK_RAD53_CHEK2_ST	Q08050	FOXM1	O96017	CHEK2	S376	R373W	373	Missense	distal	-3	no	12.514	-0.714	EPSD	ICGC;COSMIC	8.561	Loss
CAMK_RAD53_CHEK2_ST	Q08050	FOXM1	O96017	CHEK2	S376	Q382K	382	Missense	distal	6	no	12.514	12.522	EPSD	ICGC	8.561	Up-regulation
CAMK_RAD53_CHEK2_ST	Q08050	FOXM1	O96017	CHEK2	S516	P509T	509	Missense	distal	-7	no	8.646	8.035	EPSD	ICGC;COSMIC	8.561	Loss
CAMK_RAD53_CHEK2_ST	P18887	XRCC1	O96017	CHEK2	S17	S14R	14	Missense	distal	-3	no	6.457	13.314	EPSD	ICGC;COSMIC	8.561	Gain
CAMK_RAD53_CHEK2_ST	P18887	XRCC1	O96017	CHEK2	S140	S137R	137	Missense	distal	-3	no	2.802	9.660	EPSD	ICGC	8.561	Gain
CAMK_RAD53_CHEK2_ST	P18887	XRCC1	O96017	CHEK2	S151	R148L	148	Missense	distal	-3	no	13.054	5.443	EPSD	ICGC;COSMIC	8.561	Loss
CAMK_RAD53_CHEK2_ST	P18887	XRCC1	O96017	CHEK2	S184	N183K	183	Missense	proximal	-1	no	9.002	8.737	PhosphoSitePlus;EPSD	ICGC	8.561	Down-regulation
CAMK_RAD53_CHEK2_ST	P18887	XRCC1	O96017	CHEK2	T215	A221S	221	Missense	distal	6	no	10.659	10.799	EPSD	ICGC;COSMIC	8.561	Up-regulation
CAMK_RAD53_CHEK2_ST	P18887	XRCC1	O96017	CHEK2	S241	P242S	242	Missense	proximal	1	no	9.554	8.036	EPSD	ICGC	8.561	Loss
CAMK_RAD53_CHEK2_ST	P18887	XRCC1	O96017	CHEK2	S241	G244W	244	Missense	distal	3	no	9.554	10.148	EPSD	ICGC;COSMIC	8.561	Up-regulation
CAMK_RAD53_CHEK2_ST	P18887	XRCC1	O96017	CHEK2	S266	P261Q	261	Missense	distal	-5	no	9.337	9.195	EPSD	ICGC	8.561	Down-regulation
CAMK_RAD53_CHEK2_ST	P18887	XRCC1	O96017	CHEK2	S266	P261T	261	Missense	distal	-5	no	9.337	9.193	EPSD	ICGC	8.561	Down-regulation
CAMK_RAD53_CHEK2_ST	P18887	XRCC1	O96017	CHEK2	T281	T284K	284	Missense	distal	3	no	8.144	8.682	EPSD	ICGC	8.561	Gain
CAMK_RAD53_CHEK2_ST	P18887	XRCC1	O96017	CHEK2	T281	A285D	285	Missense	distal	4	no	8.144	8.688	EPSD	ICGC	8.561	Gain
CAMK_RAD53_CHEK2_ST	P18887	XRCC1	O96017	CHEK2	T358	T358M	358	Missense	central	0	yes	11.769	0.000	EPSD	ICGC;COSMIC;GDSC;CCLE	8.561	Loss
CAMK_RAD53_CHEK2_ST	P18887	XRCC1	O96017	CHEK2	T435	Q432K	432	Missense	distal	-3	no	3.891	8.756	EPSD	ICGC	8.561	Gain
CAMK_RAD53_CHEK2_ST	P18887	XRCC1	O96017	CHEK2	S447	G444E	444	Missense	distal	-3	no	10.033	8.028	EPSD	ICGC;COSMIC	8.561	Loss
CAMK_RAD53_CHEK2_ST	P18887	XRCC1	O96017	CHEK2	S447	P451T	451	Missense	distal	4	no	10.033	10.070	EPSD	ICGC	8.561	Up-regulation
CAMK_RAD53_CHEK2_ST	P18887	XRCC1	O96017	CHEK2	S447	P451H	451	Missense	distal	4	no	10.033	10.079	EPSD	ICGC	8.561	Up-regulation
CAMK_RAD53_CHEK2_ST	P18887	XRCC1	O96017	CHEK2	S447	A442E	442	Missense	distal	-5	no	10.033	9.667	EPSD	ICGC	8.561	Down-regulation
CAMK_RAD53_CHEK2_ST	P18887	XRCC1	O96017	CHEK2	S447	Q441K	441	Missense	distal	-6	no	10.033	10.044	EPSD	ICGC	8.561	Up-regulation
CAMK_RAD53_CHEK2_ST	P18887	XRCC1	O96017	CHEK2	T453	P451T	451	Missense	proximal	-2	no	8.547	8.803	EPSD	ICGC	8.561	Gain
CAMK_RAD53_CHEK2_ST	P18887	XRCC1	O96017	CHEK2	T453	P451H	451	Missense	proximal	-2	no	8.547	8.707	EPSD	ICGC	8.561	Gain
CAMK_RAD53_CHEK2_ST	P30304	CDC25A	O96017	CHEK2	S23	P25T	25	Missense	proximal	2	no	10.492	10.420	EPSD	ICGC;COSMIC	8.561	Down-regulation
CAMK_RAD53_CHEK2_ST	P30304	CDC25A	O96017	CHEK2	S107	S107Y	107	Missense	central	0	yes	16.295	0.000	EPSD	ICGC	8.561	Loss
CAMK_RAD53_CHEK2_ST	P30304	CDC25A	O96017	CHEK2	S124	H129Q	129	Missense	distal	5	no	12.958	12.978	PhosphoSitePlus;EPSD	ICGC	8.561	Up-regulation
CAMK_RAD53_CHEK2_ST	P30304	CDC25A	O96017	CHEK2	S124	P117Q	117	Missense	distal	-7	no	12.958	12.125	PhosphoSitePlus;EPSD	ICGC	8.561	Down-regulation
CAMK_RAD53_CHEK2_ST	P30304	CDC25A	O96017	CHEK2	S126	H129Q	129	Missense	distal	3	no	12.035	11.236	EPSD	ICGC	8.561	Down-regulation
CAMK_RAD53_CHEK2_ST	P30304	CDC25A	O96017	CHEK2	S178	L184I	184	Missense	distal	6	no	13.985	13.584	EPSD;PhosphoSitePlus	ICGC	8.561	Down-regulation
CAMK_RAD53_CHEK2_ST	P30304	CDC25A	O96017	CHEK2	S279	P285H	285	Missense	distal	6	no	10.580	10.653	EPSD;PhosphoSitePlus	ICGC;COSMIC	8.561	Up-regulation
CAMK_RAD53_CHEK2_ST	P30304	CDC25A	O96017	CHEK2	S287	P285H	285	Missense	proximal	-2	no	8.447	8.606	EPSD	ICGC;COSMIC	8.561	Gain
CAMK_RAD53_CHEK2_ST	P30304	CDC25A	O96017	CHEK2	S505	R506Q	506	Missense	proximal	1	no	10.310	13.905	EPSD	ICGC;COSMIC	8.561	Up-regulation
CAMK_RAD53_CHEK2_ST	P30304	CDC25A	O96017	CHEK2	S505	R502C	502	Missense	distal	-3	no	10.310	-0.613	EPSD	ICGC	8.561	Loss
CAMK_RAD53_CHEK2_ST	Q9UHR4	BAIAP2L1	O96017	CHEK2	S147	A153E	153	Missense	distal	6	no	12.676	12.528	EPSD	ICGC	8.561	Down-regulation
CAMK_RAD53_CHEK2_ST	Q9UHR4	BAIAP2L1	O96017	CHEK2	S147	L154I	154	Missense	distal	7	no	12.676	12.685	EPSD	ICGC	8.561	Up-regulation
CAMK_RAD53_CHEK2_ST	Q9UHR4	BAIAP2L1	O96017	CHEK2	T252	E245K	245	Missense	distal	-7	no	9.111	9.309	EPSD	ICGC;COSMIC	8.561	Up-regulation
CAMK_RAD53_CHEK2_ST	Q9UHR4	BAIAP2L1	O96017	CHEK2	S422	L426S	426	Missense	distal	4	no	13.937	13.618	EPSD	ICGC;COSMIC	8.561	Down-regulation
CAMK_RAD53_CHEK2_ST	Q9UHR4	BAIAP2L1	O96017	CHEK2	S422	P415H	415	Missense	distal	-7	no	13.937	14.136	EPSD	ICGC;COSMIC	8.561	Up-regulation
CAMK_RAD53_CHEK2_ST	Q9NRM7	LATS2	O96017	CHEK2	T5	A8D	8	Missense	distal	3	no	14.160	15.193	EPSD	ICGC	8.561	Up-regulation
CAMK_RAD53_CHEK2_ST	Q9NRM7	LATS2	O96017	CHEK2	T5	T9K	9	Missense	distal	4	no	14.160	14.354	EPSD	ICGC	8.561	Up-regulation
CAMK_RAD53_CHEK2_ST	Q9NRM7	LATS2	O96017	CHEK2	S172	S179L	179	Missense	distal	7	no	15.417	15.441	EPSD;PhosphoSitePlus	ICGC;COSMIC	8.561	Up-regulation
CAMK_RAD53_CHEK2_ST	Q9NRM7	LATS2	O96017	CHEK2	S172	R169W	169	Missense	distal	-3	no	15.417	2.189	EPSD;PhosphoSitePlus	ICGC	8.561	Loss
CAMK_RAD53_CHEK2_ST	Q9NRM7	LATS2	O96017	CHEK2	S172	P171H	171	Missense	proximal	-1	no	15.417	15.543	EPSD;PhosphoSitePlus	ICGC	8.561	Up-regulation
CAMK_RAD53_CHEK2_ST	Q9NRM7	LATS2	O96017	CHEK2	S172	T168K	168	Missense	distal	-4	no	15.417	16.353	EPSD;PhosphoSitePlus	ICGC	8.561	Up-regulation
CAMK_RAD53_CHEK2_ST	Q9NRM7	LATS2	O96017	CHEK2	S172	P166T	166	Missense	distal	-6	no	15.417	15.338	EPSD;PhosphoSitePlus	ICGC;COSMIC	8.561	Down-regulation
CAMK_RAD53_CHEK2_ST	Q9NRM7	LATS2	O96017	CHEK2	S274	R271C	271	Missense	distal	-3	no	14.952	4.029	EPSD	ICGC	8.561	Loss
CAMK_RAD53_CHEK2_ST	Q9NRM7	LATS2	O96017	CHEK2	S274	V269A	269	Missense	distal	-5	no	14.952	15.026	EPSD	ICGC;COSMIC	8.561	Up-regulation
CAMK_RAD53_CHEK2_ST	Q9NRM7	LATS2	O96017	CHEK2	S335	S335N	335	Missense	central	0	yes	10.962	0.000	EPSD	ICGC;COSMIC	8.561	Loss
CAMK_RAD53_CHEK2_ST	Q9NRM7	LATS2	O96017	CHEK2	S380	P384L	384	Missense	distal	4	no	18.133	18.225	EPSD;PhosphoSitePlus	ICGC;COSMIC;GDSC	8.561	Up-regulation
CAMK_RAD53_CHEK2_ST	Q9NRM7	LATS2	O96017	CHEK2	S380	E387G	387	Missense	distal	7	no	18.133	18.125	EPSD;PhosphoSitePlus	ICGC	8.561	Down-regulation
CAMK_RAD53_CHEK2_ST	Q9NRM7	LATS2	O96017	CHEK2	S835	S835R	835	Missense	central	0	yes	14.484	0.000	EPSD	ICGC	8.561	Loss
CAMK_RAD53_CHEK2_ST	Q9NRM7	LATS2	O96017	CHEK2	S872	T876N	876	Missense	distal	4	no	8.535	8.859	EPSD	ICGC;GDSC;CCLE	8.561	Gain
CAMK_RAD53_CHEK2_ST	Q9NRM7	LATS2	O96017	CHEK2	S872	G875W	875	Missense	distal	3	no	8.535	9.129	EPSD	ICGC;COSMIC	8.561	Gain
CAMK_RAD53_CHEK2_ST	Q9NRM7	LATS2	O96017	CHEK2	S872	P877Q	877	Missense	distal	5	no	8.535	8.632	EPSD	ICGC;COSMIC	8.561	Gain
CAMK_RAD53_CHEK2_ST	Q9NRM7	LATS2	O96017	CHEK2	T876	P877Q	877	Missense	proximal	1	no	7.789	10.316	EPSD	ICGC;COSMIC	8.561	Gain
CAMK_RAD53_CHEK2_ST	Q9NRM7	LATS2	O96017	CHEK2	S1064	E1067D	1067	Missense	distal	3	no	8.249	8.908	EPSD	ICGC	8.561	Gain
CAMK_RAD53_CHEK2_ST	Q9NRM7	LATS2	O96017	CHEK2	S1064	E1067K	1067	Missense	distal	3	no	8.249	8.588	EPSD	ICGC;COSMIC	8.561	Gain
CAMK_RAD53_CHEK2_ST	P61289	PSME3	O96017	CHEK2	T207	R203H	203	Missense	distal	-4	no	12.737	12.378	EPSD	ICGC;COSMIC	8.561	Down-regulation
CAMK_RAD53_CHEK2_ST	P61289	PSME3	O96017	CHEK2	T207	R204H	204	Missense	distal	-3	no	12.737	9.005	EPSD	ICGC	8.561	Down-regulation
CAMK_RAD53_CHEK2_ST	P61289	PSME3	O96017	CHEK2	S247	R244W	244	Missense	distal	-3	no	10.094	-3.134	PhosphoSitePlus	ICGC;COSMIC	8.561	Loss
CAMK_RAD53_CHEK2_ST	Q15717	ELAVL1	O96017	CHEK2	S48	R53Q	53	Missense	distal	5	no	8.866	8.771	EPSD	ICGC;COSMIC	8.561	Down-regulation
CAMK_RAD53_CHEK2_ST	Q15717	ELAVL1	O96017	CHEK2	S48	S42I	42	Missense	distal	-6	no	8.866	8.318	EPSD	ICGC;COSMIC	8.561	Loss
CAMK_RAD53_CHEK2_ST	Q15717	ELAVL1	O96017	CHEK2	S48	V46G	46	Missense	proximal	-2	no	8.866	8.725	EPSD	ICGC;COSMIC	8.561	Down-regulation
CAMK_RAD53_CHEK2_ST	Q15717	ELAVL1	O96017	CHEK2	S48	V46I	46	Missense	proximal	-2	no	8.866	8.880	EPSD	ICGC;COSMIC	8.561	Up-regulation
CAMK_RAD53_CHEK2_ST	Q15717	ELAVL1	O96017	CHEK2	S88	Y95C	95	Missense	distal	7	no	14.048	14.026	EPSD;PhosphoSitePlus	ICGC	8.561	Down-regulation
CAMK_RAD53_CHEK2_ST	Q15717	ELAVL1	O96017	CHEK2	S100	P98L	98	Missense	proximal	-2	no	10.228	10.179	EPSD;PhosphoSitePlus	ICGC;COSMIC	8.561	Down-regulation
CAMK_RAD53_CHEK2_ST	Q15717	ELAVL1	O96017	CHEK2	S100	R97H	97	Missense	distal	-3	no	10.228	6.495	EPSD;PhosphoSitePlus	ICGC	8.561	Loss
CAMK_RAD53_CHEK2_ST	Q15717	ELAVL1	O96017	CHEK2	S100	Y95C	95	Missense	distal	-5	no	10.228	10.748	EPSD;PhosphoSitePlus	ICGC	8.561	Up-regulation
CAMK_RAD53_CHEK2_ST	Q15717	ELAVL1	O96017	CHEK2	T118	G112R	112	Missense	distal	-6	no	14.819	15.040	PhosphoSitePlus;EPSD	ICGC;COSMIC	8.561	Up-regulation
CAMK_RAD53_CHEK2_ST	Q15717	ELAVL1	O96017	CHEK2	T118	R115W	115	Missense	distal	-3	no	14.819	1.591	PhosphoSitePlus;EPSD	ICGC;COSMIC;GDSC;CCLE	8.561	Loss
CAMK_RAD53_CHEK2_ST	Q15717	ELAVL1	O96017	CHEK2	T118	T116N	116	Missense	proximal	-2	no	14.819	14.412	PhosphoSitePlus;EPSD	ICGC	8.561	Down-regulation
CAMK_RAD53_CHEK2_ST	Q15717	ELAVL1	O96017	CHEK2	T118	T118N	118	Missense	central	0	yes	14.819	0.000	PhosphoSitePlus;EPSD	ICGC	8.561	Loss
CAMK_RAD53_CHEK2_ST	Q15717	ELAVL1	O96017	CHEK2	T118	G112W	112	Missense	distal	-6	no	14.819	14.318	PhosphoSitePlus;EPSD	ICGC;COSMIC	8.561	Down-regulation
CAMK_RAD53_CHEK2_ST	Q15717	ELAVL1	O96017	CHEK2	T118	Q119K	119	Missense	proximal	1	no	14.819	11.639	PhosphoSitePlus;EPSD	ICGC;COSMIC	8.561	Down-regulation
CAMK_RAD53_CHEK2_ST	Q15717	ELAVL1	O96017	CHEK2	T118	L113H	113	Missense	distal	-5	no	14.819	14.636	PhosphoSitePlus;EPSD	ICGC	8.561	Down-regulation
CAMK_RAD53_CHEK2_ST	Q15717	ELAVL1	O96017	CHEK2	S221	F218L	218	Missense	distal	-3	no	-1.609	9.011	EPSD	ICGC	8.561	Gain
CAMK_RAD53_CHEK2_ST	P29590	PML	O96017	CHEK2	S117	V118L	118	Missense	proximal	1	no	16.197	17.796	PhosphoSitePlus	ICGC	8.561	Up-regulation
CAMK_RAD53_CHEK2_ST	P29590	PML	O96017	CHEK2	S117	R115L	115	Missense	proximal	-2	no	16.197	15.643	PhosphoSitePlus	ICGC;COSMIC	8.561	Down-regulation
CAMK_RAD53_CHEK2_ST	P29590	PML	O96017	CHEK2	S208	S214L	214	Missense	distal	6	no	11.438	11.370	EPSD	ICGC;COSMIC	8.561	Down-regulation
CAMK_RAD53_CHEK2_ST	P29590	PML	O96017	CHEK2	T391	V398L	398	Missense	distal	7	no	8.629	8.634	EPSD	ICGC	8.561	Up-regulation
CAMK_RAD53_CHEK2_ST	P29590	PML	O96017	CHEK2	T391	S388Y	388	Missense	distal	-3	no	8.629	1.914	EPSD	ICGC;COSMIC	8.561	Loss
CAMK_RAD53_CHEK2_ST	P29590	PML	O96017	CHEK2	T391	C389R	389	Missense	proximal	-2	no	8.629	9.155	EPSD	ICGC;COSMIC	8.561	Up-regulation
CAMK_RAD53_CHEK2_ST	P29590	PML	O96017	CHEK2	T391	S388F	388	Missense	distal	-3	no	8.629	-2.745	EPSD	ICGC;COSMIC	8.561	Loss
CAMK_RAD53_CHEK2_ST	P29590	PML	O96017	CHEK2	T409	P410A	410	Missense	proximal	1	no	8.908	8.971	EPSD	ICGC;COSMIC	8.561	Up-regulation
CAMK_RAD53_CHEK2_ST	P29590	PML	O96017	CHEK2	T409	A407S	407	Missense	proximal	-2	no	8.908	8.743	EPSD	ICGC;COSMIC	8.561	Down-regulation
CAMK_RAD53_CHEK2_ST	P29590	PML	O96017	CHEK2	T409	A407T	407	Missense	proximal	-2	no	8.908	8.762	EPSD	ICGC;COSMIC	8.561	Down-regulation
CAMK_RAD53_CHEK2_ST	P29590	PML	O96017	CHEK2	S480	K487N	487	Missense	distal	7	no	14.890	14.902	EPSD	ICGC;COSMIC	8.561	Up-regulation
CAMK_RAD53_CHEK2_ST	P29590	PML	O96017	CHEK2	S480	P485H	485	Missense	distal	5	no	14.890	14.967	EPSD	ICGC;COSMIC	8.561	Up-regulation
CAMK_RAD53_CHEK2_ST	P29590	PML	O96017	CHEK2	S480	R486S	486	Missense	distal	6	no	14.890	14.825	EPSD	ICGC;COSMIC	8.561	Down-regulation
CAMK_RAD53_CHEK2_ST	P29590	PML	O96017	CHEK2	S512	Q508H	508	Missense	distal	-4	no	8.833	8.376	EPSD	ICGC	8.561	Loss
CAMK_RAD53_CHEK2_ST	P29590	PML	O96017	CHEK2	S512	S505F	505	Missense	distal	-7	no	8.833	5.439	EPSD	ICGC	8.561	Loss
CAMK_RAD53_CHEK2_ST	P29590	PML	O96017	CHEK2	T513	Q508H	508	Missense	distal	-5	no	12.490	12.238	EPSD	ICGC	8.561	Down-regulation
CAMK_RAD53_CHEK2_ST	P29590	PML	O96017	CHEK2	S518	P525L	525	Missense	distal	7	no	11.658	11.673	EPSD	ICGC;COSMIC;GDSC;CCLE	8.561	Up-regulation
CAMK_RAD53_CHEK2_ST	P29590	PML	O96017	CHEK2	S547	A549V	549	Missense	proximal	2	no	9.517	9.362	EPSD	ICGC;COSMIC	8.561	Down-regulation
CAMK_RAD53_CHEK2_ST	P29590	PML	O96017	CHEK2	S547	G550R	550	Missense	distal	3	no	9.517	8.718	EPSD	ICGC;COSMIC	8.561	Down-regulation
CAMK_RAD53_CHEK2_ST	P29590	PML	O96017	CHEK2	S547	G550W	550	Missense	distal	3	no	9.517	10.111	EPSD	ICGC;COSMIC	8.561	Up-regulation
CAMK_RAD53_CHEK2_ST	P29590	PML	O96017	CHEK2	S723	R717H	717	Missense	distal	-6	no	8.814	8.772	EPSD	ICGC;COSMIC	8.561	Down-regulation
CAMK_RAD53_CHEK2_ST	P29590	PML	O96017	CHEK2	S804	V803M	803	Missense	proximal	-1	no	10.647	10.292	EPSD	ICGC	8.561	Down-regulation
CAMK_RAD53_CHEK2_ST	P29590	PML	O96017	CHEK2	S828	R825H	825	Missense	distal	-3	no	14.637	10.905	EPSD	ICGC;COSMIC;GDSC	8.561	Down-regulation
CAMK_RAD53_CHEK2_ST	P29590	PML	O96017	CHEK2	S828	K821R	821	Missense	distal	-7	no	14.637	14.905	EPSD	ICGC;COSMIC	8.561	Up-regulation
CAMK_RAD53_CHEK2_ST	P29590	PML	O96017	CHEK2	S828	L834V	834	Missense	distal	6	no	14.637	14.387	EPSD	ICGC;COSMIC	8.561	Down-regulation
CAMK_RAD53_CHEK2_ST	P21127	CDK11B	O96017	CHEK2	S38	R45W	45	Missense	distal	7	no	9.284	9.337	EPSD	ICGC	8.561	Up-regulation
CAMK_RAD53_CHEK2_ST	P21127	CDK11B	O96017	CHEK2	S72	S72Y	72	Missense	central	0	yes	14.163	0.000	EPSD	ICGC;COSMIC	8.561	Loss
CAMK_RAD53_CHEK2_ST	Q01094	E2F1	O96017	CHEK2	S121	P122L	122	Missense	proximal	1	no	8.292	9.582	EPSD	ICGC	8.561	Gain
CAMK_RAD53_CHEK2_ST	Q01094	E2F1	O96017	CHEK2	S313	P308T	308	Missense	distal	-5	no	10.615	10.471	EPSD	ICGC	8.561	Down-regulation
CAMK_RAD53_CHEK2_ST	Q01094	E2F1	O96017	CHEK2	S313	S318A	318	Missense	distal	5	no	10.615	10.592	EPSD	ICGC	8.561	Down-regulation
CAMK_RAD53_CHEK2_ST	Q01094	E2F1	O96017	CHEK2	S364	V369M	369	Missense	distal	5	no	16.027	15.969	PhosphoSitePlus	ICGC	8.561	Down-regulation
CAMK_RAD53_CHEK2_ST	Q01094	E2F1	O96017	CHEK2	S364	R361Q	361	Missense	distal	-3	no	16.027	6.078	PhosphoSitePlus	ICGC	8.561	Loss
CAMK_RAD53_CHEK2_ST	Q01094	E2F1	O96017	CHEK2	S364	S360F	360	Missense	distal	-4	no	16.027	13.146	PhosphoSitePlus	ICGC	8.561	Down-regulation
CAMK_RAD53_CHEK2_ST	P10636	MAPT	O96017	CHEK2	T30	E36D	36	Missense	distal	6	no	8.933	8.808	EPSD	ICGC;COSMIC	8.561	Down-regulation
CAMK_RAD53_CHEK2_ST	P10636	MAPT	O96017	CHEK2	T30	Q26L	26	Missense	distal	-4	no	8.933	7.473	EPSD	ICGC;COSMIC	8.561	Loss
CAMK_RAD53_CHEK2_ST	P10636	MAPT	O96017	CHEK2	T30	D34Y	34	Missense	distal	4	no	8.933	8.874	EPSD	ICGC;COSMIC	8.561	Down-regulation
CAMK_RAD53_CHEK2_ST	P10636	MAPT	O96017	CHEK2	T167	P160L	160	Missense	distal	-7	no	11.981	11.272	EPSD	ICGC;COSMIC	8.561	Down-regulation
CAMK_RAD53_CHEK2_ST	P10636	MAPT	O96017	CHEK2	T167	R164T	164	Missense	distal	-3	no	11.981	3.438	EPSD	ICGC;COSMIC	8.561	Loss
CAMK_RAD53_CHEK2_ST	P10636	MAPT	O96017	CHEK2	T167	A166T	166	Missense	proximal	-1	no	11.981	12.069	EPSD	ICGC	8.561	Up-regulation
CAMK_RAD53_CHEK2_ST	P10636	MAPT	O96017	CHEK2	S171	R164T	164	Missense	distal	-7	no	11.678	11.233	EPSD	ICGC;COSMIC	8.561	Down-regulation
CAMK_RAD53_CHEK2_ST	P10636	MAPT	O96017	CHEK2	S171	A166T	166	Missense	distal	-5	no	11.678	12.192	EPSD	ICGC	8.561	Up-regulation
CAMK_RAD53_CHEK2_ST	P10636	MAPT	O96017	CHEK2	S214	G208C	208	Missense	distal	-6	no	11.886	11.856	EPSD	ICGC;COSMIC	8.561	Down-regulation
CAMK_RAD53_CHEK2_ST	P10636	MAPT	O96017	CHEK2	S214	R211S	211	Missense	distal	-3	no	11.886	5.028	EPSD	ICGC;COSMIC	8.561	Loss
CAMK_RAD53_CHEK2_ST	P10636	MAPT	O96017	CHEK2	S214	G213E	213	Missense	proximal	-1	no	11.886	11.734	EPSD	ICGC;COSMIC	8.561	Down-regulation
CAMK_RAD53_CHEK2_ST	P10636	MAPT	O96017	CHEK2	S238	P239Q	239	Missense	proximal	1	no	6.843	9.370	EPSD	ICGC;COSMIC	8.561	Gain
CAMK_RAD53_CHEK2_ST	P10636	MAPT	O96017	CHEK2	S341	T346I	346	Missense	distal	5	no	14.117	13.950	EPSD	ICGC;COSMIC	8.561	Down-regulation
CAMK_RAD53_CHEK2_ST	P10636	MAPT	O96017	CHEK2	S341	A337V	337	Missense	distal	-4	no	14.117	12.618	EPSD	ICGC	8.561	Down-regulation
CAMK_RAD53_CHEK2_ST	P10636	MAPT	O96017	CHEK2	S341	D345E	345	Missense	distal	4	no	14.117	13.480	EPSD	ICGC;COSMIC	8.561	Down-regulation
CAMK_RAD53_CHEK2_ST	P54132	BLM	O96017	CHEK2	S33	P30R	30	Missense	distal	-3	no	7.194	12.920	EPSD	ICGC;COSMIC	8.561	Gain
CAMK_RAD53_CHEK2_ST	P54132	BLM	O96017	CHEK2	S72	E69K	69	Missense	distal	-3	no	6.186	9.013	EPSD	ICGC;COSMIC	8.561	Gain
CAMK_RAD53_CHEK2_ST	P54132	BLM	O96017	CHEK2	T99	P94S	94	Missense	distal	-5	no	10.248	9.688	EPSD	ICGC	8.561	Down-regulation
CAMK_RAD53_CHEK2_ST	P54132	BLM	O96017	CHEK2	T182	Q184H	184	Missense	proximal	2	no	15.547	15.727	PhosphoSitePlus	ICGC;COSMIC	8.561	Up-regulation
CAMK_RAD53_CHEK2_ST	P54132	BLM	O96017	CHEK2	S269	K272N	272	Missense	distal	3	no	11.009	10.861	EPSD	ICGC;COSMIC	8.561	Down-regulation
CAMK_RAD53_CHEK2_ST	P54132	BLM	O96017	CHEK2	S367	Q365L	365	Missense	proximal	-2	no	11.751	11.510	EPSD	ICGC;COSMIC	8.561	Down-regulation
CAMK_RAD53_CHEK2_ST	P54132	BLM	O96017	CHEK2	S434	P438S	438	Missense	distal	4	no	13.150	12.922	EPSD	ICGC;COSMIC	8.561	Down-regulation
CAMK_RAD53_CHEK2_ST	P54132	BLM	O96017	CHEK2	S579	S579Y	579	Missense	central	0	yes	8.916	0.000	EPSD	ICGC;COSMIC	8.561	Loss
CAMK_RAD53_CHEK2_ST	P54132	BLM	O96017	CHEK2	S579	S580F	580	Missense	proximal	1	no	8.916	13.672	EPSD	ICGC;COSMIC	8.561	Up-regulation
CAMK_RAD53_CHEK2_ST	P54132	BLM	O96017	CHEK2	T581	S579Y	579	Missense	proximal	-2	no	9.390	8.240	EPSD	ICGC;COSMIC	8.561	Loss
CAMK_RAD53_CHEK2_ST	P54132	BLM	O96017	CHEK2	T581	S580F	580	Missense	proximal	-1	no	9.390	9.790	EPSD	ICGC;COSMIC	8.561	Up-regulation
CAMK_RAD53_CHEK2_ST	P54132	BLM	O96017	CHEK2	S602	S601Y	601	Missense	proximal	-1	no	12.179	12.725	EPSD	ICGC;COSMIC	8.561	Up-regulation
CAMK_RAD53_CHEK2_ST	P54132	BLM	O96017	CHEK2	S646	R643H	643	Missense	distal	-3	no	13.457	9.724	EPSD	ICGC;COSMIC;GDSC	8.561	Down-regulation
CAMK_RAD53_CHEK2_ST	P54132	BLM	O96017	CHEK2	S646	Q645K	645	Missense	proximal	-1	no	13.457	13.965	EPSD	ICGC;COSMIC	8.561	Up-regulation
CAMK_RAD53_CHEK2_ST	P54132	BLM	O96017	CHEK2	S646	R643L	643	Missense	distal	-3	no	13.457	5.845	EPSD	ICGC;COSMIC	8.561	Loss
CAMK_RAD53_CHEK2_ST	P54132	BLM	O96017	CHEK2	S646	S648N	648	Missense	proximal	2	no	13.457	13.315	EPSD	ICGC	8.561	Down-regulation
CAMK_RAD53_CHEK2_ST	P54132	BLM	O96017	CHEK2	S729	V724F	724	Missense	distal	-5	no	9.186	9.311	EPSD	ICGC	8.561	Up-regulation
CAMK_RAD53_CHEK2_ST	P54132	BLM	O96017	CHEK2	S1296	P1297Q	1297	Missense	proximal	1	no	8.073	10.600	EPSD	ICGC;COSMIC	8.561	Gain
CAMK_RAD53_CHEK2_ST	P54132	BLM	O96017	CHEK2	S1300	P1297Q	1297	Missense	distal	-3	no	9.037	4.814	EPSD	ICGC;COSMIC	8.561	Loss
CAMK_RAD53_CHEK2_ST	P54132	BLM	O96017	CHEK2	S1375	S1375G	1375	Missense	central	0	yes	8.723	0.000	EPSD	ICGC	8.561	Loss
CAMK_RAD53_CHEK2_ST	P54132	BLM	O96017	CHEK2	S1375	S1368P	1368	Missense	distal	-7	no	8.723	8.487	EPSD	ICGC;COSMIC	8.561	Loss
CAMK_RAD53_CHEK2_ST	P54132	BLM	O96017	CHEK2	S1375	G1378V	1378	Missense	distal	3	no	8.723	8.678	EPSD	ICGC	8.561	Down-regulation
CAMK_RAD53_CHEK2_ST	P54132	BLM	O96017	CHEK2	S1381	S1375G	1375	Missense	distal	-6	no	9.404	9.135	EPSD	ICGC	8.561	Down-regulation
CAMK_RAD53_CHEK2_ST	P54132	BLM	O96017	CHEK2	S1381	G1378V	1378	Missense	distal	-3	no	9.404	5.865	EPSD	ICGC	8.561	Loss
CAMK_RAD53_CHEK2_ST	P54132	BLM	O96017	CHEK2	S1394	G1397E	1397	Missense	distal	3	no	8.758	8.422	EPSD	ICGC	8.561	Loss
CAMK_RAD53_CHEK2_ST	P38398	BRCA1	O96017	CHEK2	T509	R507T	507	Missense	proximal	-2	no	11.278	11.028	EPSD	ICGC;COSMIC	8.561	Down-regulation
CAMK_RAD53_CHEK2_ST	P38398	BRCA1	O96017	CHEK2	S510	R507T	507	Missense	distal	-3	no	12.417	3.874	EPSD	ICGC;COSMIC	8.561	Loss
CAMK_RAD53_CHEK2_ST	P38398	BRCA1	O96017	CHEK2	S615	N609I	609	Missense	distal	-6	no	10.681	10.502	EPSD	ICGC	8.561	Down-regulation
CAMK_RAD53_CHEK2_ST	P38398	BRCA1	O96017	CHEK2	S616	N609I	609	Missense	distal	-7	no	12.246	11.160	EPSD	ICGC	8.561	Down-regulation
CAMK_RAD53_CHEK2_ST	P38398	BRCA1	O96017	CHEK2	S632	N635K	635	Missense	distal	3	no	13.672	13.820	EPSD	ICGC	8.561	Up-regulation
CAMK_RAD53_CHEK2_ST	P38398	BRCA1	O96017	CHEK2	S868	S868C	868	Missense	central	0	yes	10.273	0.000	EPSD	ICGC;COSMIC	8.561	Loss
CAMK_RAD53_CHEK2_ST	P38398	BRCA1	O96017	CHEK2	S1164	E1167D	1167	Missense	distal	3	no	10.404	11.063	EPSD	ICGC;COSMIC	8.561	Up-regulation
CAMK_RAD53_CHEK2_ST	P38398	BRCA1	O96017	CHEK2	S1164	S1164F	1164	Missense	central	0	yes	10.404	0.000	EPSD	ICGC;COSMIC	8.561	Loss
CAMK_RAD53_CHEK2_ST	P38398	BRCA1	O96017	CHEK2	S1164	K1160N	1160	Missense	distal	-4	no	10.404	9.153	EPSD	ICGC;COSMIC	8.561	Down-regulation
CAMK_RAD53_CHEK2_ST	P38398	BRCA1	O96017	CHEK2	S1191	H1197N	1197	Missense	distal	6	no	14.099	13.444	EPSD	ICGC;COSMIC	8.561	Down-regulation
CAMK_RAD53_CHEK2_ST	P40337	VHL	O96017	CHEK2	S72	P71R	71	Missense	proximal	-1	no	15.594	15.466	EPSD	ICGC;COSMIC	8.561	Down-regulation
CAMK_RAD53_CHEK2_ST	P40337	VHL	O96017	CHEK2	S72	V74G	74	Missense	proximal	2	no	15.594	15.734	EPSD	ICGC;COSMIC	8.561	Up-regulation
CAMK_RAD53_CHEK2_ST	P40337	VHL	O96017	CHEK2	S72	N78I	78	Missense	distal	6	no	15.594	15.628	EPSD	ICGC;COSMIC	8.561	Up-regulation
CAMK_RAD53_CHEK2_ST	P40337	VHL	O96017	CHEK2	S72	N78S	78	Missense	distal	6	no	15.594	16.098	EPSD	ICGC;COSMIC	8.561	Up-regulation
CAMK_RAD53_CHEK2_ST	P40337	VHL	O96017	CHEK2	S72	S65L	65	Missense	distal	-7	no	15.594	14.648	EPSD	ICGC;COSMIC	8.561	Down-regulation
CAMK_RAD53_CHEK2_ST	P40337	VHL	O96017	CHEK2	S72	N78K	78	Missense	distal	6	no	15.594	15.944	EPSD	ICGC;COSMIC;CCLE	8.561	Up-regulation
CAMK_RAD53_CHEK2_ST	P40337	VHL	O96017	CHEK2	S72	S65P	65	Missense	distal	-7	no	15.594	15.357	EPSD	ICGC;COSMIC	8.561	Down-regulation
CAMK_RAD53_CHEK2_ST	P40337	VHL	O96017	CHEK2	S72	R79P	79	Missense	distal	7	no	15.594	15.601	EPSD	ICGC;COSMIC	8.561	Up-regulation
CAMK_RAD53_CHEK2_ST	P40337	VHL	O96017	CHEK2	S72	R79H	79	Missense	distal	7	no	15.594	15.600	EPSD	ICGC;COSMIC	8.561	Up-regulation
CAMK_RAD53_CHEK2_ST	P40337	VHL	O96017	CHEK2	S72	V74A	74	Missense	proximal	2	no	15.594	15.748	EPSD	ICGC;COSMIC	8.561	Up-regulation
CAMK_RAD53_CHEK2_ST	P40337	VHL	O96017	CHEK2	T100	Y98D	98	Missense	proximal	-2	no	8.443	8.898	EPSD	ICGC;COSMIC	8.561	Gain
CAMK_RAD53_CHEK2_ST	P40337	VHL	O96017	CHEK2	S111	L116I	116	Missense	distal	5	no	14.752	14.759	PhosphoSitePlus	ICGC	8.561	Up-regulation
CAMK_RAD53_CHEK2_ST	P40337	VHL	O96017	CHEK2	S111	I109N	109	Missense	proximal	-2	no	14.752	14.627	PhosphoSitePlus	ICGC;COSMIC	8.561	Down-regulation
CAMK_RAD53_CHEK2_ST	P40337	VHL	O96017	CHEK2	S111	Y112C	112	Missense	proximal	1	no	14.752	15.063	PhosphoSitePlus	ICGC;COSMIC	8.561	Up-regulation
CAMK_RAD53_CHEK2_ST	P40337	VHL	O96017	CHEK2	S111	S111R	111	Missense	central	0	yes	14.752	0.000	PhosphoSitePlus	ICGC;COSMIC	8.561	Loss
CAMK_RAD53_CHEK2_ST	P40337	VHL	O96017	CHEK2	S111	S111G	111	Missense	central	0	yes	14.752	0.000	PhosphoSitePlus	ICGC;COSMIC	8.561	Loss
CAMK_RAD53_CHEK2_ST	P40337	VHL	O96017	CHEK2	S111	H115Q	115	Missense	distal	4	no	14.752	14.589	PhosphoSitePlus	ICGC;COSMIC;CCLE	8.561	Down-regulation
CAMK_RAD53_CHEK2_ST	P40337	VHL	O96017	CHEK2	S111	S111I	111	Missense	central	0	yes	14.752	0.000	PhosphoSitePlus	ICGC;COSMIC;CCLE	8.561	Loss
CAMK_RAD53_CHEK2_ST	P40337	VHL	O96017	CHEK2	S111	W117L	117	Missense	distal	6	no	14.752	15.496	PhosphoSitePlus	ICGC;COSMIC	8.561	Up-regulation
CAMK_RAD53_CHEK2_ST	P40337	VHL	O96017	CHEK2	S111	T105R	105	Missense	distal	-6	no	14.752	14.907	PhosphoSitePlus	ICGC;COSMIC	8.561	Up-regulation
CAMK_RAD53_CHEK2_ST	P40337	VHL	O96017	CHEK2	S111	H115R	115	Missense	distal	4	no	14.752	14.525	PhosphoSitePlus	ICGC;COSMIC	8.561	Down-regulation
CAMK_RAD53_CHEK2_ST	P40337	VHL	O96017	CHEK2	S111	W117G	117	Missense	distal	6	no	14.752	15.337	PhosphoSitePlus	ICGC;COSMIC	8.561	Up-regulation
CAMK_RAD53_CHEK2_ST	Q13263	TRIM28	O96017	CHEK2	S41	A40V	40	Missense	proximal	-1	no	8.256	8.732	EPSD	ICGC	8.561	Gain
CAMK_RAD53_CHEK2_ST	Q13263	TRIM28	O96017	CHEK2	S43	A40V	40	Missense	distal	-3	no	9.443	5.713	EPSD	ICGC	8.561	Loss
CAMK_RAD53_CHEK2_ST	Q13263	TRIM28	O96017	CHEK2	S43	A44T	44	Missense	proximal	1	no	9.443	9.468	EPSD	ICGC	8.561	Up-regulation
CAMK_RAD53_CHEK2_ST	Q13263	TRIM28	O96017	CHEK2	S43	A38S	38	Missense	distal	-5	no	9.443	9.542	EPSD	ICGC;COSMIC	8.561	Up-regulation
CAMK_RAD53_CHEK2_ST	Q13263	TRIM28	O96017	CHEK2	S50	G54A	54	Missense	distal	4	no	10.211	9.926	EPSD	ICGC	8.561	Down-regulation
CAMK_RAD53_CHEK2_ST	Q13263	TRIM28	O96017	CHEK2	S50	A44T	44	Missense	distal	-6	no	10.211	10.233	EPSD	ICGC	8.561	Up-regulation
CAMK_RAD53_CHEK2_ST	Q13263	TRIM28	O96017	CHEK2	S102	A95V	95	Missense	distal	-7	no	9.036	8.440	EPSD	ICGC;COSMIC	8.561	Loss
CAMK_RAD53_CHEK2_ST	Q13263	TRIM28	O96017	CHEK2	S102	A95T	95	Missense	distal	-7	no	9.036	9.253	EPSD	ICGC;COSMIC	8.561	Up-regulation
CAMK_RAD53_CHEK2_ST	Q13263	TRIM28	O96017	CHEK2	S102	G107R	107	Missense	distal	5	no	9.036	9.278	EPSD	ICGC;COSMIC	8.561	Up-regulation
CAMK_RAD53_CHEK2_ST	Q13263	TRIM28	O96017	CHEK2	S285	V284M	284	Missense	proximal	-1	no	11.409	11.055	EPSD	ICGC	8.561	Down-regulation
CAMK_RAD53_CHEK2_ST	Q13263	TRIM28	O96017	CHEK2	T415	P413L	413	Missense	proximal	-2	no	11.020	10.971	EPSD	ICGC	8.561	Down-regulation
CAMK_RAD53_CHEK2_ST	Q13263	TRIM28	O96017	CHEK2	T415	R412C	412	Missense	distal	-3	no	11.020	0.097	EPSD	ICGC;COSMIC	8.561	Loss
CAMK_RAD53_CHEK2_ST	Q13263	TRIM28	O96017	CHEK2	S417	P413L	413	Missense	distal	-4	no	9.214	8.437	EPSD	ICGC	8.561	Loss
CAMK_RAD53_CHEK2_ST	Q13263	TRIM28	O96017	CHEK2	S417	R412C	412	Missense	distal	-5	no	9.214	9.065	EPSD	ICGC;COSMIC	8.561	Down-regulation
CAMK_RAD53_CHEK2_ST	Q13263	TRIM28	O96017	CHEK2	S473	G476S	476	Missense	distal	3	no	14.111	13.411	PhosphoSitePlus	ICGC;COSMIC	8.561	Down-regulation
CAMK_RAD53_CHEK2_ST	Q13263	TRIM28	O96017	CHEK2	T541	A548T	548	Missense	distal	7	no	10.217	10.219	EPSD	ICGC;COSMIC	8.561	Up-regulation
CAMK_RAD53_CHEK2_ST	Q13263	TRIM28	O96017	CHEK2	T541	A539E	539	Missense	proximal	-2	no	10.217	9.665	EPSD	ICGC	8.561	Down-regulation
CAMK_RAD53_CHEK2_ST	Q13263	TRIM28	O96017	CHEK2	S594	S598N	598	Missense	distal	4	no	11.064	11.653	EPSD	ICGC;GDSC;CCLE	8.561	Up-regulation
CAMK_RAD53_CHEK2_ST	Q13263	TRIM28	O96017	CHEK2	S598	L603V	603	Missense	distal	5	no	10.812	10.858	EPSD	ICGC;COSMIC	8.561	Up-regulation
CAMK_RAD53_CHEK2_ST	Q13263	TRIM28	O96017	CHEK2	S598	S598N	598	Missense	central	0	yes	10.812	0.000	EPSD	ICGC;GDSC;CCLE	8.561	Loss
CAMK_RAD53_CHEK2_ST	Q13263	TRIM28	O96017	CHEK2	S757	Y755N	755	Missense	proximal	-2	no	8.330	9.091	EPSD	ICGC	8.561	Gain
CAMK_RAD53_CHEK2_ST	Q13263	TRIM28	O96017	CHEK2	S824	G830S	830	Missense	distal	6	no	8.389	8.617	EPSD	ICGC;COSMIC	8.561	Gain
CAMK_RAD53_CHEK2_ST	O15151	MDM4	O96017	CHEK2	T151	L158V	158	Missense	distal	7	no	8.770	8.766	EPSD	ICGC;COSMIC	8.561	Down-regulation
CAMK_RAD53_CHEK2_ST	O15151	MDM4	O96017	CHEK2	S342	I349T	349	Missense	distal	7	no	10.639	10.620	PhosphoSitePlus;EPSD	ICGC;COSMIC	8.561	Down-regulation
CAMK_RAD53_CHEK2_ST	P23560	BDNF	O96017	CHEK2	T62	E68Q	68	Missense	distal	6	no	8.883	9.010	PhosphoSitePlus	ICGC;COSMIC	8.561	Up-regulation
CAMK_RAD53_CHEK2_ST	P23560	BDNF	O96017	CHEK2	T62	V66M	66	Missense	distal	4	no	8.883	8.717	PhosphoSitePlus	ICGC;COSMIC	8.561	Down-regulation
CAMK_RAD53_CHEK2_ST	P23560	BDNF	O96017	CHEK2	T62	G55S	55	Missense	distal	-7	no	8.883	9.356	PhosphoSitePlus	ICGC;COSMIC	8.561	Up-regulation
CAMK_RAD53_CHEK2_ST	P23560	BDNF	O96017	CHEK2	T62	D61E	61	Missense	proximal	-1	no	8.883	8.535	PhosphoSitePlus	ICGC;COSMIC	8.561	Loss
CAMK_RAD53_CHEK2_ST	P23560	BDNF	O96017	CHEK2	T62	E64K	64	Missense	proximal	2	no	8.883	8.969	PhosphoSitePlus	ICGC;COSMIC;CCLE	8.561	Up-regulation
CAMK_RAD53_CHEK2_ST	P30307	CDC25C	O96017	CHEK2	S38	L33P	33	Missense	distal	-5	no	15.082	15.293	EPSD	ICGC;COSMIC	8.561	Up-regulation
CAMK_RAD53_CHEK2_ST	P30307	CDC25C	O96017	CHEK2	S216	E219D	219	Missense	distal	3	no	15.096	15.756	PhosphoSitePlus	ICGC;COSMIC	8.561	Up-regulation
CAMK_RAD53_CHEK2_ST	P30307	CDC25C	O96017	CHEK2	S449	G456V	456	Missense	distal	7	no	13.832	13.838	EPSD	ICGC;COSMIC	8.561	Up-regulation
CAMK_RAD53_CHEK2_ST	P30307	CDC25C	O96017	CHEK2	S451	G456V	456	Missense	distal	5	no	9.972	10.003	EPSD	ICGC;COSMIC	8.561	Up-regulation
CAMK_RAD53_CHEK2_ST	P06400	RB1	O96017	CHEK2	S350	L343F	343	Missense	distal	-7	no	8.629	6.181	EPSD	ICGC;COSMIC	8.561	Loss
CAMK_RAD53_CHEK2_ST	P06400	RB1	O96017	CHEK2	S350	Q354H	354	Missense	distal	4	no	8.629	8.792	EPSD	ICGC;COSMIC	8.561	Up-regulation
CAMK_RAD53_CHEK2_ST	P06400	RB1	O96017	CHEK2	T778	P783L	783	Missense	distal	5	no	11.420	11.354	EPSD	ICGC	8.561	Down-regulation
CAMK_RAD53_CHEK2_ST	P06400	RB1	O96017	CHEK2	S780	P783L	783	Missense	distal	3	no	9.151	9.136	EPSD	ICGC	8.561	Down-regulation
CAMK_RAD53_CHEK2_ST	O60673	REV3L	O96017	CHEK2	S105	F102S	102	Missense	distal	-3	no	-1.907	9.467	EPSD	ICGC;COSMIC	8.561	Gain
CAMK_RAD53_CHEK2_ST	O60673	REV3L	O96017	CHEK2	S435	P434Q	434	Missense	proximal	-1	no	12.643	12.535	EPSD	ICGC;COSMIC	8.561	Down-regulation
CAMK_RAD53_CHEK2_ST	O60673	REV3L	O96017	CHEK2	S470	S470C	470	Missense	central	0	yes	11.540	0.000	EPSD	ICGC;COSMIC	8.561	Loss
CAMK_RAD53_CHEK2_ST	O60673	REV3L	O96017	CHEK2	S470	S470Y	470	Missense	central	0	yes	11.540	0.000	EPSD	ICGC;COSMIC	8.561	Loss
CAMK_RAD53_CHEK2_ST	O60673	REV3L	O96017	CHEK2	S545	S545Y	545	Missense	central	0	yes	10.208	0.000	EPSD	ICGC;COSMIC	8.561	Loss
CAMK_RAD53_CHEK2_ST	O60673	REV3L	O96017	CHEK2	S545	S545C	545	Missense	central	0	yes	10.208	0.000	EPSD	ICGC;COSMIC	8.561	Loss
CAMK_RAD53_CHEK2_ST	O60673	REV3L	O96017	CHEK2	S968	P973H	973	Missense	distal	5	no	14.181	14.258	EPSD	ICGC;COSMIC	8.561	Up-regulation
CAMK_RAD53_CHEK2_ST	O60673	REV3L	O96017	CHEK2	S968	S961T	961	Missense	distal	-7	no	14.181	13.334	EPSD	ICGC	8.561	Down-regulation
CAMK_RAD53_CHEK2_ST	O60673	REV3L	O96017	CHEK2	S1075	R1072K	1072	Missense	distal	-3	no	19.271	14.186	PhosphoSitePlus	ICGC;COSMIC	8.561	Down-regulation
CAMK_RAD53_CHEK2_ST	O60673	REV3L	O96017	CHEK2	S1119	F1112V	1112	Missense	distal	-7	no	7.964	9.697	EPSD	ICGC;COSMIC	8.561	Gain
CAMK_RAD53_CHEK2_ST	O60673	REV3L	O96017	CHEK2	S1130	R1127H	1127	Missense	distal	-3	no	16.877	13.144	EPSD	ICGC;COSMIC;CCLE	8.561	Down-regulation
CAMK_RAD53_CHEK2_ST	O60673	REV3L	O96017	CHEK2	T1224	T1224I	1224	Missense	central	0	yes	16.756	0.000	EPSD	ICGC;COSMIC	8.561	Loss
CAMK_RAD53_CHEK2_ST	O60673	REV3L	O96017	CHEK2	T1225	T1224I	1224	Missense	proximal	-1	no	11.775	12.257	EPSD	ICGC;COSMIC	8.561	Up-regulation
CAMK_RAD53_CHEK2_ST	O60673	REV3L	O96017	CHEK2	S1515	Q1508E	1508	Missense	distal	-7	no	10.333	10.533	EPSD	ICGC;COSMIC	8.561	Up-regulation
CAMK_RAD53_CHEK2_ST	O60673	REV3L	O96017	CHEK2	S1515	S1518L	1518	Missense	distal	3	no	10.333	10.502	EPSD	ICGC	8.561	Up-regulation
CAMK_RAD53_CHEK2_ST	O60673	REV3L	O96017	CHEK2	S1515	V1514A	1514	Missense	proximal	-1	no	10.333	9.857	EPSD	ICGC	8.561	Down-regulation
CAMK_RAD53_CHEK2_ST	O60673	REV3L	O96017	CHEK2	T1547	S1552Y	1552	Missense	distal	5	no	8.962	8.648	EPSD	ICGC	8.561	Down-regulation
CAMK_RAD53_CHEK2_ST	O60673	REV3L	O96017	CHEK2	T1547	S1552F	1552	Missense	distal	5	no	8.962	8.574	EPSD	ICGC;COSMIC	8.561	Down-regulation
CAMK_RAD53_CHEK2_ST	O60673	REV3L	O96017	CHEK2	S1576	T1578M	1578	Missense	proximal	2	no	11.716	11.554	EPSD	ICGC;COSMIC	8.561	Down-regulation
CAMK_RAD53_CHEK2_ST	O60673	REV3L	O96017	CHEK2	T1578	T1578M	1578	Missense	central	0	yes	11.860	0.000	EPSD	ICGC;COSMIC	8.561	Loss
CAMK_RAD53_CHEK2_ST	O60673	REV3L	O96017	CHEK2	T1722	E1726V	1726	Missense	distal	4	no	12.721	13.147	EPSD	ICGC;COSMIC	8.561	Up-regulation
CAMK_RAD53_CHEK2_ST	O60673	REV3L	O96017	CHEK2	S1757	T1752K	1752	Missense	distal	-5	no	14.520	13.814	EPSD	ICGC	8.561	Down-regulation
CAMK_RAD53_CHEK2_ST	O60673	REV3L	O96017	CHEK2	S1796	Q1792R	1792	Missense	distal	-4	no	9.596	9.498	EPSD	ICGC;COSMIC	8.561	Down-regulation
CAMK_RAD53_CHEK2_ST	O60673	REV3L	O96017	CHEK2	S1865	P1862H	1862	Missense	distal	-3	no	8.224	10.218	EPSD	ICGC;COSMIC	8.561	Gain
CAMK_RAD53_CHEK2_ST	O60673	REV3L	O96017	CHEK2	S1967	P1968H	1968	Missense	proximal	1	no	11.688	10.921	EPSD	ICGC;COSMIC	8.561	Down-regulation
CAMK_RAD53_CHEK2_ST	O60673	REV3L	O96017	CHEK2	S1967	G1966E	1966	Missense	proximal	-1	no	11.688	11.536	EPSD	ICGC;COSMIC	8.561	Down-regulation
CAMK_RAD53_CHEK2_ST	O60673	REV3L	O96017	CHEK2	S1967	T1960N	1960	Missense	distal	-7	no	11.688	11.162	EPSD	ICGC	8.561	Down-regulation
CAMK_RAD53_CHEK2_ST	O60673	REV3L	O96017	CHEK2	T2187	S2183Y	2183	Missense	distal	-4	no	9.802	7.278	EPSD	ICGC	8.561	Loss
CAMK_RAD53_CHEK2_ST	O60673	REV3L	O96017	CHEK2	T2259	N2252S	2252	Missense	distal	-7	no	7.407	8.780	EPSD	ICGC;COSMIC	8.561	Gain
CAMK_RAD53_CHEK2_ST	O60673	REV3L	O96017	CHEK2	T2363	Y2361C	2361	Missense	proximal	-2	no	10.748	11.641	EPSD	ICGC;COSMIC	8.561	Up-regulation
CAMK_RAD53_CHEK2_ST	O60673	REV3L	O96017	CHEK2	T2363	L2366R	2366	Missense	distal	3	no	10.748	10.481	EPSD	ICGC	8.561	Down-regulation
CAMK_RAD53_CHEK2_ST	O60673	REV3L	O96017	CHEK2	S2430	D2435E	2435	Missense	distal	5	no	10.190	10.298	EPSD	ICGC	8.561	Up-regulation
CAMK_RAD53_CHEK2_ST	O60673	REV3L	O96017	CHEK2	S2430	R2431L	2431	Missense	proximal	1	no	10.190	12.548	EPSD	ICGC;COSMIC;GDSC;CCLE	8.561	Up-regulation
CAMK_RAD53_CHEK2_ST	O60673	REV3L	O96017	CHEK2	S2714	R2720C	2720	Missense	distal	6	no	9.330	9.125	EPSD	ICGC;COSMIC	8.561	Down-regulation
CAMK_RAD53_CHEK2_ST	O60673	REV3L	O96017	CHEK2	S2884	T2880K	2880	Missense	distal	-4	no	11.433	12.369	EPSD	ICGC	8.561	Up-regulation
CAMK_CAMK2_CAMK2D_ST	Q08289	CACNB2	Q13557	CAMK2D	S218	P220S	220	Missense	proximal	2	no	51.476	53.897	EPSD	ICGC;COSMIC	37.605	Up-regulation
CAMK_CAMK2_CAMK2D_ST	Q08289	CACNB2	Q13557	CAMK2D	T219	P220S	220	Missense	proximal	1	no	42.441	46.074	EPSD	ICGC;COSMIC	37.605	Up-regulation
CAMK_CAMK2_CAMK2D_ST	Q08289	CACNB2	Q13557	CAMK2D	S514	S521F	521	Missense	distal	7	no	56.286	56.936	EPSD	ICGC;COSMIC	37.605	Up-regulation
CAMK_CAMK2_CAMK2D_ST	Q08289	CACNB2	Q13557	CAMK2D	S514	E518K	518	Missense	distal	4	no	56.286	56.741	EPSD	ICGC;COSMIC	37.605	Up-regulation
CAMK_CAMK2_CAMK2D_ST	Q08289	CACNB2	Q13557	CAMK2D	T554	E561K	561	Missense	distal	7	no	87.151	87.229	EPSD	ICGC;COSMIC	37.605	Up-regulation
CAMK_CAMK2_CAMK2D_ST	P51787	KCNQ1	Q13557	CAMK2D	S27	A28V	28	Missense	proximal	1	no	34.194	40.626	EPSD	ICGC;COSMIC	37.605	Gain
CAMK_CAMK2_CAMK2D_ST	P51787	KCNQ1	Q13557	CAMK2D	T404	S409G	409	Missense	distal	5	no	37.472	38.422	EPSD	ICGC;COSMIC	37.605	Gain
CAMK_CAMK2_CAMK2D_ST	P51787	KCNQ1	Q13557	CAMK2D	T470	M476I	476	Missense	distal	6	no	43.465	44.100	EPSD	ICGC;COSMIC;CCLE	37.605	Up-regulation
CAMK_CAMK2_CAMK2D_ST	P51787	KCNQ1	Q13557	CAMK2D	S484	M480I	480	Missense	distal	-4	no	44.012	45.766	PhosphoSitePlus;EPSD	ICGC;COSMIC	37.605	Up-regulation
CAMK_CAMK2_CAMK2D_ST	P56524	HDAC4	Q13557	CAMK2D	S210	P217L	217	Missense	distal	7	no	71.895	72.812	PhosphoSitePlus	ICGC	37.605	Up-regulation
CAMK_CAMK2_CAMK2D_ST	P56524	HDAC4	Q13557	CAMK2D	S620	G623W	623	Missense	distal	3	no	38.429	29.541	EPSD	ICGC	37.605	Loss
CAMK_CAMK2_CAMK2D_ST	P56524	HDAC4	Q13557	CAMK2D	S628	G623W	623	Missense	distal	-5	no	51.960	52.108	EPSD	ICGC	37.605	Up-regulation
CAMK_CAMK2_CAMK2D_ST	Q8WZ42	TTN	Q13557	CAMK2D	T114	R109L	109	Missense	distal	-5	no	48.847	49.058	EPSD	ICGC;COSMIC	37.605	Up-regulation
CAMK_CAMK2_CAMK2D_ST	Q8WZ42	TTN	Q13557	CAMK2D	T114	V115M	115	Missense	proximal	1	no	48.847	53.721	EPSD	ICGC;COSMIC;GDSC;CCLE	37.605	Up-regulation
CAMK_CAMK2_CAMK2D_ST	Q8WZ42	TTN	Q13557	CAMK2D	S263	P266Q	266	Missense	distal	3	no	44.737	43.457	EPSD	ICGC	37.605	Down-regulation
CAMK_CAMK2_CAMK2D_ST	Q8WZ42	TTN	Q13557	CAMK2D	S263	R264G	264	Missense	proximal	1	no	44.737	39.982	EPSD	ICGC	37.605	Down-regulation
CAMK_CAMK2_CAMK2D_ST	Q8WZ42	TTN	Q13557	CAMK2D	T267	P266Q	266	Missense	proximal	-1	no	42.936	44.394	EPSD	ICGC	37.605	Up-regulation
CAMK_CAMK2_CAMK2D_ST	Q8WZ42	TTN	Q13557	CAMK2D	T267	R264G	264	Missense	distal	-3	no	42.936	-0.022	EPSD	ICGC	37.605	Loss
CAMK_CAMK2_CAMK2D_ST	Q8WZ42	TTN	Q13557	CAMK2D	T267	I271T	271	Missense	distal	4	no	42.936	41.928	EPSD	ICGC	37.605	Down-regulation
CAMK_CAMK2_CAMK2D_ST	Q8WZ42	TTN	Q13557	CAMK2D	S270	P266Q	266	Missense	distal	-4	no	46.240	44.930	EPSD	ICGC	37.605	Down-regulation
CAMK_CAMK2_CAMK2D_ST	Q8WZ42	TTN	Q13557	CAMK2D	S270	R264G	264	Missense	distal	-6	no	46.240	44.423	EPSD	ICGC	37.605	Down-regulation
CAMK_CAMK2_CAMK2D_ST	Q8WZ42	TTN	Q13557	CAMK2D	S270	I271T	271	Missense	proximal	1	no	46.240	36.041	EPSD	ICGC	37.605	Loss
CAMK_CAMK2_CAMK2D_ST	Q8WZ42	TTN	Q13557	CAMK2D	S284	R279W	279	Missense	distal	-5	no	37.197	39.133	EPSD	ICGC;COSMIC;GDSC	37.605	Gain
CAMK_CAMK2_CAMK2D_ST	Q8WZ42	TTN	Q13557	CAMK2D	T300	P301S	301	Missense	proximal	1	no	34.566	38.199	EPSD	ICGC	37.605	Gain
CAMK_CAMK2_CAMK2D_ST	Q8WZ42	TTN	Q13557	CAMK2D	S308	P301S	301	Missense	distal	-7	no	36.459	39.710	EPSD	ICGC	37.605	Gain
CAMK_CAMK2_CAMK2D_ST	Q8WZ42	TTN	Q13557	CAMK2D	T334	R328C	328	Missense	distal	-6	no	52.348	49.477	EPSD	ICGC;COSMIC	37.605	Down-regulation
CAMK_CAMK2_CAMK2D_ST	Q8WZ42	TTN	Q13557	CAMK2D	T334	T334I	334	Missense	central	0	yes	52.348	0.000	EPSD	ICGC	37.605	Loss
CAMK_CAMK2_CAMK2D_ST	Q8WZ42	TTN	Q13557	CAMK2D	S353	K346M	346	Missense	distal	-7	no	51.118	49.883	EPSD	ICGC	37.605	Down-regulation
CAMK_CAMK2_CAMK2D_ST	Q8WZ42	TTN	Q13557	CAMK2D	S353	A352D	352	Missense	proximal	-1	no	51.118	49.601	EPSD	ICGC	37.605	Down-regulation
CAMK_CAMK2_CAMK2D_ST	Q8WZ42	TTN	Q13557	CAMK2D	S353	A352T	352	Missense	proximal	-1	no	51.118	52.773	EPSD	ICGC;COSMIC	37.605	Up-regulation
CAMK_CAMK2_CAMK2D_ST	Q8WZ42	TTN	Q13557	CAMK2D	T559	A564T	564	Missense	distal	5	no	46.008	44.944	EPSD	ICGC	37.605	Down-regulation
CAMK_CAMK2_CAMK2D_ST	Q8WZ42	TTN	Q13557	CAMK2D	T559	A554E	554	Missense	distal	-5	no	46.008	44.684	EPSD	ICGC;COSMIC	37.605	Down-regulation
CAMK_CAMK2_CAMK2D_ST	Q8WZ42	TTN	Q13557	CAMK2D	T559	A564E	564	Missense	distal	5	no	46.008	43.361	EPSD	ICGC	37.605	Down-regulation
CAMK_CAMK2_CAMK2D_ST	Q8WZ42	TTN	Q13557	CAMK2D	S813	H815D	815	Missense	proximal	2	no	35.082	46.656	EPSD	ICGC;COSMIC	37.605	Gain
CAMK_CAMK2_CAMK2D_ST	Q8WZ42	TTN	Q13557	CAMK2D	S905	T907N	907	Missense	proximal	2	no	40.093	39.750	EPSD	ICGC	37.605	Down-regulation
CAMK_CAMK2_CAMK2D_ST	Q8WZ42	TTN	Q13557	CAMK2D	S905	V911F	911	Missense	distal	6	no	40.093	38.097	EPSD	ICGC;COSMIC	37.605	Down-regulation
CAMK_CAMK2_CAMK2D_ST	Q8WZ42	TTN	Q13557	CAMK2D	S905	K900R	900	Missense	distal	-5	no	40.093	40.068	EPSD	ICGC;COSMIC;CCLE	37.605	Down-regulation
CAMK_CAMK2_CAMK2D_ST	Q8WZ42	TTN	Q13557	CAMK2D	T910	V911F	911	Missense	proximal	1	no	34.525	40.910	EPSD	ICGC;COSMIC	37.605	Gain
CAMK_CAMK2_CAMK2D_ST	Q8WZ42	TTN	Q13557	CAMK2D	T1067	Q1073E	1073	Missense	distal	6	no	41.928	38.177	EPSD	ICGC;COSMIC	37.605	Down-regulation
CAMK_CAMK2_CAMK2D_ST	Q8WZ42	TTN	Q13557	CAMK2D	T1067	M1064K	1064	Missense	distal	-3	no	41.928	40.885	EPSD	ICGC;COSMIC	37.605	Down-regulation
CAMK_CAMK2_CAMK2D_ST	Q8WZ42	TTN	Q13557	CAMK2D	S1418	I1415M	1415	Missense	distal	-3	no	39.060	41.799	EPSD	ICGC	37.605	Up-regulation
CAMK_CAMK2_CAMK2D_ST	Q8WZ42	TTN	Q13557	CAMK2D	S1418	P1424T	1424	Missense	distal	6	no	39.060	32.528	EPSD	ICGC	37.605	Loss
CAMK_CAMK2_CAMK2D_ST	Q8WZ42	TTN	Q13557	CAMK2D	S1418	R1421Q	1421	Missense	distal	3	no	39.060	38.164	EPSD	ICGC	37.605	Down-regulation
CAMK_CAMK2_CAMK2D_ST	Q8WZ42	TTN	Q13557	CAMK2D	T1546	E1551K	1551	Missense	distal	5	no	38.235	38.686	EPSD	ICGC	37.605	Up-regulation
CAMK_CAMK2_CAMK2D_ST	Q8WZ42	TTN	Q13557	CAMK2D	T1609	A1614V	1614	Missense	distal	5	no	50.647	50.435	EPSD	ICGC;COSMIC	37.605	Down-regulation
CAMK_CAMK2_CAMK2D_ST	Q8WZ42	TTN	Q13557	CAMK2D	T1609	R1605K	1605	Missense	distal	-4	no	50.647	49.425	EPSD	ICGC;COSMIC	37.605	Down-regulation
CAMK_CAMK2_CAMK2D_ST	Q8WZ42	TTN	Q13557	CAMK2D	T1609	R1605I	1605	Missense	distal	-4	no	50.647	49.073	EPSD	ICGC;COSMIC	37.605	Down-regulation
CAMK_CAMK2_CAMK2D_ST	Q8WZ42	TTN	Q13557	CAMK2D	T1609	E1612K	1612	Missense	distal	3	no	50.647	44.628	EPSD	ICGC	37.605	Down-regulation
CAMK_CAMK2_CAMK2D_ST	Q8WZ42	TTN	Q13557	CAMK2D	T1609	P1602L	1602	Missense	distal	-7	no	50.647	57.239	EPSD	ICGC	37.605	Up-regulation
CAMK_CAMK2_CAMK2D_ST	Q8WZ42	TTN	Q13557	CAMK2D	T1609	L1615I	1615	Missense	distal	6	no	50.647	50.534	EPSD	ICGC;COSMIC	37.605	Down-regulation
CAMK_CAMK2_CAMK2D_ST	Q8WZ42	TTN	Q13557	CAMK2D	S1622	A1626S	1626	Missense	distal	4	no	37.251	38.673	EPSD	ICGC;COSMIC	37.605	Gain
CAMK_CAMK2_CAMK2D_ST	Q8WZ42	TTN	Q13557	CAMK2D	S1622	S1625Y	1625	Missense	distal	3	no	37.251	40.696	EPSD	ICGC	37.605	Gain
CAMK_CAMK2_CAMK2D_ST	Q8WZ42	TTN	Q13557	CAMK2D	S1799	I1793N	1793	Missense	distal	-6	no	25.828	38.343	EPSD	ICGC;COSMIC	37.605	Gain
CAMK_CAMK2_CAMK2D_ST	Q8WZ42	TTN	Q13557	CAMK2D	S2086	I2080N	2080	Missense	distal	-6	no	26.973	39.488	EPSD	ICGC;COSMIC	37.605	Gain
CAMK_CAMK2_CAMK2D_ST	Q8WZ42	TTN	Q13557	CAMK2D	T2193	M2191T	2191	Missense	proximal	-2	no	44.487	43.360	EPSD	ICGC;COSMIC	37.605	Down-regulation
CAMK_CAMK2_CAMK2D_ST	Q8WZ42	TTN	Q13557	CAMK2D	T2193	E2197K	2197	Missense	distal	4	no	44.487	44.942	EPSD	ICGC;COSMIC	37.605	Up-regulation
CAMK_CAMK2_CAMK2D_ST	Q8WZ42	TTN	Q13557	CAMK2D	T2193	E2187K	2187	Missense	distal	-6	no	44.487	42.503	EPSD	ICGC;COSMIC;GDSC;CCLE	37.605	Down-regulation
CAMK_CAMK2_CAMK2D_ST	Q8WZ42	TTN	Q13557	CAMK2D	T2507	R2501Q	2501	Missense	distal	-6	no	45.070	47.933	EPSD	ICGC	37.605	Up-regulation
CAMK_CAMK2_CAMK2D_ST	Q8WZ42	TTN	Q13557	CAMK2D	S2749	V2745I	2745	Missense	distal	-4	no	45.043	42.653	EPSD	ICGC;COSMIC	37.605	Down-regulation
CAMK_CAMK2_CAMK2D_ST	Q8WZ42	TTN	Q13557	CAMK2D	S2749	S2756F	2756	Missense	distal	7	no	45.043	45.693	EPSD	ICGC	37.605	Up-regulation
CAMK_CAMK2_CAMK2D_ST	Q8WZ42	TTN	Q13557	CAMK2D	T3119	R3113H	3113	Missense	distal	-6	no	55.190	53.015	EPSD	ICGC	37.605	Down-regulation
CAMK_CAMK2_CAMK2D_ST	Q8WZ42	TTN	Q13557	CAMK2D	T3119	R3113C	3113	Missense	distal	-6	no	55.190	52.320	EPSD	ICGC;COSMIC	37.605	Down-regulation
CAMK_CAMK2_CAMK2D_ST	Q8WZ42	TTN	Q13557	CAMK2D	T3119	M3121L	3121	Missense	proximal	2	no	55.190	59.561	EPSD	ICGC;COSMIC	37.605	Up-regulation
CAMK_CAMK2_CAMK2D_ST	Q8WZ42	TTN	Q13557	CAMK2D	T3119	S3118F	3118	Missense	proximal	-1	no	55.190	51.918	EPSD	ICGC;COSMIC	37.605	Down-regulation
CAMK_CAMK2_CAMK2D_ST	Q8WZ42	TTN	Q13557	CAMK2D	S3208	Q3212K	3212	Missense	distal	4	no	41.212	41.065	EPSD	ICGC;COSMIC	37.605	Down-regulation
CAMK_CAMK2_CAMK2D_ST	Q8WZ42	TTN	Q13557	CAMK2D	S3208	S3208P	3208	Missense	central	0	yes	41.212	0.000	EPSD	ICGC	37.605	Loss
CAMK_CAMK2_CAMK2D_ST	Q8WZ42	TTN	Q13557	CAMK2D	S3208	F3206L	3206	Missense	proximal	-2	no	41.212	41.079	EPSD	ICGC;COSMIC	37.605	Down-regulation
CAMK_CAMK2_CAMK2D_ST	Q8WZ42	TTN	Q13557	CAMK2D	S3379	D3381Y	3381	Missense	proximal	2	no	41.287	26.435	EPSD	ICGC	37.605	Loss
CAMK_CAMK2_CAMK2D_ST	Q8WZ42	TTN	Q13557	CAMK2D	S3458	S3458F	3458	Missense	central	0	yes	37.764	0.000	EPSD	ICGC;COSMIC	37.605	Loss
CAMK_CAMK2_CAMK2D_ST	Q8WZ42	TTN	Q13557	CAMK2D	S3458	E3451K	3451	Missense	distal	-7	no	37.764	44.031	EPSD	ICGC;COSMIC	37.605	Up-regulation
CAMK_CAMK2_CAMK2D_ST	Q8WZ42	TTN	Q13557	CAMK2D	S3458	E3463K	3463	Missense	distal	5	no	37.764	38.215	EPSD	ICGC;COSMIC	37.605	Up-regulation
CAMK_CAMK2_CAMK2D_ST	Q8WZ42	TTN	Q13557	CAMK2D	S3458	E3464K	3464	Missense	distal	6	no	37.764	38.311	EPSD	ICGC;COSMIC	37.605	Up-regulation
CAMK_CAMK2_CAMK2D_ST	Q8WZ42	TTN	Q13557	CAMK2D	S3458	E3454K	3454	Missense	distal	-4	no	37.764	41.019	EPSD	ICGC	37.605	Up-regulation
CAMK_CAMK2_CAMK2D_ST	Q8WZ42	TTN	Q13557	CAMK2D	S3664	L3661I	3661	Missense	distal	-3	no	30.734	39.467	EPSD	ICGC;COSMIC	37.605	Gain
CAMK_CAMK2_CAMK2D_ST	Q8WZ42	TTN	Q13557	CAMK2D	T3934	Q3941R	3941	Missense	distal	7	no	53.679	53.415	EPSD	ICGC;COSMIC	37.605	Down-regulation
CAMK_CAMK2_CAMK2D_ST	Q8WZ42	TTN	Q13557	CAMK2D	T3934	L3935V	3935	Missense	proximal	1	no	53.679	55.848	EPSD	ICGC;COSMIC	37.605	Up-regulation
CAMK_CAMK2_CAMK2D_ST	Q8WZ42	TTN	Q13557	CAMK2D	T3934	Q3941K	3941	Missense	distal	7	no	53.679	54.904	EPSD	ICGC	37.605	Up-regulation
CAMK_CAMK2_CAMK2D_ST	Q8WZ42	TTN	Q13557	CAMK2D	T3934	A3940T	3940	Missense	distal	6	no	53.679	50.086	EPSD	ICGC;COSMIC	37.605	Down-regulation
CAMK_CAMK2_CAMK2D_ST	Q8WZ42	TTN	Q13557	CAMK2D	T3934	V3933G	3933	Missense	proximal	-1	no	53.679	53.114	EPSD	ICGC;COSMIC	37.605	Down-regulation
CAMK_CAMK2_CAMK2D_ST	Q8WZ42	TTN	Q13557	CAMK2D	T3934	R3929K	3929	Missense	distal	-5	no	53.679	53.704	EPSD	ICGC	37.605	Up-regulation
CAMK_CAMK2_CAMK2D_ST	Q8WZ42	TTN	Q13557	CAMK2D	T3934	R3929S	3929	Missense	distal	-5	no	53.679	54.628	EPSD	ICGC;COSMIC	37.605	Up-regulation
CAMK_CAMK2_CAMK2D_ST	Q8WZ42	TTN	Q13557	CAMK2D	T3934	R3932I	3932	Missense	proximal	-2	no	53.679	53.299	EPSD	ICGC	37.605	Down-regulation
CAMK_CAMK2_CAMK2D_ST	Q8WZ42	TTN	Q13557	CAMK2D	S4065	E4072K	4072	Missense	distal	7	no	48.809	48.888	EPSD	ICGC;COSMIC	37.605	Up-regulation
CAMK_CAMK2_CAMK2D_ST	Q8WZ42	TTN	Q13557	CAMK2D	S4065	D4059G	4059	Missense	distal	-6	no	48.809	53.599	EPSD	ICGC;COSMIC;CCLE	37.605	Up-regulation
CAMK_CAMK2_CAMK2D_ST	Q8WZ42	TTN	Q13557	CAMK2D	S4065	E4064K	4064	Missense	proximal	-1	no	48.809	49.204	EPSD	ICGC;COSMIC	37.605	Up-regulation
CAMK_CAMK2_CAMK2D_ST	Q8WZ42	TTN	Q13557	CAMK2D	S4065	K4063E	4063	Missense	proximal	-2	no	48.809	48.571	EPSD	ICGC;COSMIC	37.605	Down-regulation
CAMK_CAMK2_CAMK2D_ST	Q8WZ42	TTN	Q13557	CAMK2D	S4065	L4061F	4061	Missense	distal	-4	no	48.809	47.556	EPSD	ICGC	37.605	Down-regulation
CAMK_CAMK2_CAMK2D_ST	Q8WZ42	TTN	Q13557	CAMK2D	S4065	P4071L	4071	Missense	distal	6	no	48.809	42.466	EPSD	ICGC;COSMIC	37.605	Down-regulation
CAMK_CAMK2_CAMK2D_ST	Q8WZ42	TTN	Q13557	CAMK2D	S4065	D4059N	4059	Missense	distal	-6	no	48.809	61.971	EPSD	ICGC;COSMIC	37.605	Up-regulation
CAMK_CAMK2_CAMK2D_ST	Q8WZ42	TTN	Q13557	CAMK2D	S4065	P4071S	4071	Missense	distal	6	no	48.809	42.908	EPSD	ICGC;COSMIC	37.605	Down-regulation
CAMK_CAMK2_CAMK2D_ST	Q8WZ42	TTN	Q13557	CAMK2D	S4065	L4061I	4061	Missense	distal	-4	no	48.809	50.483	EPSD	ICGC	37.605	Up-regulation
CAMK_CAMK2_CAMK2D_ST	Q8WZ42	TTN	Q13557	CAMK2D	S4068	E4072K	4072	Missense	distal	4	no	44.994	45.449	EPSD	ICGC;COSMIC	37.605	Up-regulation
CAMK_CAMK2_CAMK2D_ST	Q8WZ42	TTN	Q13557	CAMK2D	S4068	R4075I	4075	Missense	distal	7	no	44.994	46.339	EPSD	ICGC;COSMIC	37.605	Up-regulation
CAMK_CAMK2_CAMK2D_ST	Q8WZ42	TTN	Q13557	CAMK2D	S4068	R4075S	4075	Missense	distal	7	no	44.994	44.836	EPSD	ICGC;COSMIC	37.605	Down-regulation
CAMK_CAMK2_CAMK2D_ST	Q8WZ42	TTN	Q13557	CAMK2D	S4068	E4064K	4064	Missense	distal	-4	no	44.994	48.249	EPSD	ICGC;COSMIC	37.605	Up-regulation
CAMK_CAMK2_CAMK2D_ST	Q8WZ42	TTN	Q13557	CAMK2D	S4068	E4073Q	4073	Missense	distal	5	no	44.994	47.911	EPSD	ICGC;COSMIC	37.605	Up-regulation
CAMK_CAMK2_CAMK2D_ST	Q8WZ42	TTN	Q13557	CAMK2D	S4068	K4063E	4063	Missense	distal	-5	no	44.994	46.170	EPSD	ICGC;COSMIC	37.605	Up-regulation
CAMK_CAMK2_CAMK2D_ST	Q8WZ42	TTN	Q13557	CAMK2D	S4068	R4075K	4075	Missense	distal	7	no	44.994	46.484	EPSD	ICGC;COSMIC	37.605	Up-regulation
CAMK_CAMK2_CAMK2D_ST	Q8WZ42	TTN	Q13557	CAMK2D	S4068	L4061F	4061	Missense	distal	-7	no	44.994	38.990	EPSD	ICGC	37.605	Down-regulation
CAMK_CAMK2_CAMK2D_ST	Q8WZ42	TTN	Q13557	CAMK2D	S4068	P4071L	4071	Missense	distal	3	no	44.994	36.375	EPSD	ICGC;COSMIC	37.605	Loss
CAMK_CAMK2_CAMK2D_ST	Q8WZ42	TTN	Q13557	CAMK2D	S4068	Q4074E	4074	Missense	distal	6	no	44.994	41.243	EPSD	ICGC;COSMIC	37.605	Down-regulation
CAMK_CAMK2_CAMK2D_ST	Q8WZ42	TTN	Q13557	CAMK2D	S4068	P4071S	4071	Missense	distal	3	no	44.994	46.266	EPSD	ICGC;COSMIC	37.605	Up-regulation
CAMK_CAMK2_CAMK2D_ST	Q8WZ42	TTN	Q13557	CAMK2D	S4068	L4061I	4061	Missense	distal	-7	no	44.994	44.421	EPSD	ICGC	37.605	Down-regulation
CAMK_CAMK2_CAMK2D_ST	Q8WZ42	TTN	Q13557	CAMK2D	S4430	D4427N	4427	Missense	distal	-3	no	21.709	38.694	EPSD	ICGC;COSMIC	37.605	Gain
CAMK_CAMK2_CAMK2D_ST	Q8WZ42	TTN	Q13557	CAMK2D	S4486	L4487I	4487	Missense	proximal	1	no	41.087	48.979	EPSD	ICGC	37.605	Up-regulation
CAMK_CAMK2_CAMK2D_ST	Q8WZ42	TTN	Q13557	CAMK2D	S4486	K4485T	4485	Missense	proximal	-1	no	41.087	41.508	EPSD	ICGC;COSMIC	37.605	Up-regulation
CAMK_CAMK2_CAMK2D_ST	Q8WZ42	TTN	Q13557	CAMK2D	S4486	T4489S	4489	Missense	distal	3	no	41.087	47.751	EPSD	ICGC;COSMIC	37.605	Up-regulation
CAMK_CAMK2_CAMK2D_ST	Q8WZ42	TTN	Q13557	CAMK2D	S4486	T4488K	4488	Missense	proximal	2	no	41.087	40.427	EPSD	ICGC;COSMIC	37.605	Down-regulation
CAMK_CAMK2_CAMK2D_ST	Q8WZ42	TTN	Q13557	CAMK2D	S4486	K4485N	4485	Missense	proximal	-1	no	41.087	40.321	EPSD	ICGC;COSMIC	37.605	Down-regulation
CAMK_CAMK2_CAMK2D_ST	Q8WZ42	TTN	Q13557	CAMK2D	S4486	F4490V	4490	Missense	distal	4	no	41.087	40.074	EPSD	ICGC	37.605	Down-regulation
CAMK_CAMK2_CAMK2D_ST	Q8WZ42	TTN	Q13557	CAMK2D	T4725	L4722R	4722	Missense	distal	-3	no	18.509	40.344	EPSD	ICGC;COSMIC	37.605	Gain
CAMK_CAMK2_CAMK2D_ST	Q8WZ42	TTN	Q13557	CAMK2D	S5083	A5089T	5089	Missense	distal	6	no	38.068	34.476	EPSD	ICGC;COSMIC	37.605	Loss
CAMK_CAMK2_CAMK2D_ST	Q8WZ42	TTN	Q13557	CAMK2D	S5083	D5084G	5084	Missense	proximal	1	no	38.068	42.993	EPSD	ICGC;COSMIC	37.605	Up-regulation
CAMK_CAMK2_CAMK2D_ST	Q8WZ42	TTN	Q13557	CAMK2D	S5083	R5087M	5087	Missense	distal	4	no	38.068	37.746	EPSD	ICGC;COSMIC	37.605	Down-regulation
CAMK_CAMK2_CAMK2D_ST	Q8WZ42	TTN	Q13557	CAMK2D	S5083	G5077C	5077	Missense	distal	-6	no	38.068	37.015	EPSD	ICGC;COSMIC	37.605	Loss
CAMK_CAMK2_CAMK2D_ST	Q8WZ42	TTN	Q13557	CAMK2D	S5083	K5078I	5078	Missense	distal	-5	no	38.068	38.323	EPSD	ICGC;COSMIC	37.605	Up-regulation
CAMK_CAMK2_CAMK2D_ST	Q8WZ42	TTN	Q13557	CAMK2D	S5083	A5081T	5081	Missense	proximal	-2	no	38.068	37.601	EPSD	ICGC;COSMIC	37.605	Loss
CAMK_CAMK2_CAMK2D_ST	Q8WZ42	TTN	Q13557	CAMK2D	S5083	G5077D	5077	Missense	distal	-6	no	38.068	33.279	EPSD	ICGC	37.605	Loss
CAMK_CAMK2_CAMK2D_ST	Q8WZ42	TTN	Q13557	CAMK2D	S5083	E5079K	5079	Missense	distal	-4	no	38.068	41.323	EPSD	ICGC;COSMIC	37.605	Up-regulation
CAMK_CAMK2_CAMK2D_ST	Q8WZ42	TTN	Q13557	CAMK2D	S5083	S5083Y	5083	Missense	central	0	yes	38.068	0.000	EPSD	ICGC	37.605	Loss
CAMK_CAMK2_CAMK2D_ST	Q8WZ42	TTN	Q13557	CAMK2D	S5123	S5120R	5120	Missense	distal	-3	no	28.338	44.512	EPSD	ICGC	37.605	Gain
CAMK_CAMK2_CAMK2D_ST	Q8WZ42	TTN	Q13557	CAMK2D	T5155	L5152M	5152	Missense	distal	-3	no	48.875	60.346	EPSD	ICGC;COSMIC	37.605	Up-regulation
CAMK_CAMK2_CAMK2D_ST	Q8WZ42	TTN	Q13557	CAMK2D	T5155	T5160A	5160	Missense	distal	5	no	48.875	49.939	EPSD	ICGC;COSMIC	37.605	Up-regulation
CAMK_CAMK2_CAMK2D_ST	Q8WZ42	TTN	Q13557	CAMK2D	T5155	A5149E	5149	Missense	distal	-6	no	48.875	50.257	EPSD	ICGC	37.605	Up-regulation
CAMK_CAMK2_CAMK2D_ST	Q8WZ42	TTN	Q13557	CAMK2D	T5155	G5158R	5158	Missense	distal	3	no	48.875	52.086	EPSD	ICGC;COSMIC	37.605	Up-regulation
CAMK_CAMK2_CAMK2D_ST	Q8WZ42	TTN	Q13557	CAMK2D	T5155	S5154N	5154	Missense	proximal	-1	no	48.875	47.846	EPSD	ICGC	37.605	Down-regulation
CAMK_CAMK2_CAMK2D_ST	Q8WZ42	TTN	Q13557	CAMK2D	T5155	S5154C	5154	Missense	proximal	-1	no	48.875	47.633	EPSD	ICGC;COSMIC	37.605	Down-regulation
CAMK_CAMK2_CAMK2D_ST	Q8WZ42	TTN	Q13557	CAMK2D	T5155	P5161L	5161	Missense	distal	6	no	48.875	42.531	EPSD	ICGC	37.605	Down-regulation
CAMK_CAMK2_CAMK2D_ST	Q8WZ42	TTN	Q13557	CAMK2D	T5155	Q5157R	5157	Missense	proximal	2	no	48.875	48.122	EPSD	ICGC;COSMIC	37.605	Down-regulation
CAMK_CAMK2_CAMK2D_ST	Q8WZ42	TTN	Q13557	CAMK2D	T5358	W5353S	5353	Missense	distal	-5	no	53.250	52.264	EPSD	ICGC;COSMIC	37.605	Down-regulation
CAMK_CAMK2_CAMK2D_ST	Q8WZ42	TTN	Q13557	CAMK2D	T5358	D5356H	5356	Missense	proximal	-2	no	53.250	53.340	EPSD	ICGC;COSMIC	37.605	Up-regulation
CAMK_CAMK2_CAMK2D_ST	Q8WZ42	TTN	Q13557	CAMK2D	T5358	S5362T	5362	Missense	distal	4	no	53.250	52.373	EPSD	ICGC;COSMIC	37.605	Down-regulation
CAMK_CAMK2_CAMK2D_ST	Q8WZ42	TTN	Q13557	CAMK2D	T5358	R5361Q	5361	Missense	distal	3	no	53.250	52.354	EPSD	ICGC;COSMIC	37.605	Down-regulation
CAMK_CAMK2_CAMK2D_ST	Q8WZ42	TTN	Q13557	CAMK2D	T5358	F5354L	5354	Missense	distal	-4	no	53.250	54.504	EPSD	ICGC;COSMIC	37.605	Up-regulation
CAMK_CAMK2_CAMK2D_ST	Q8WZ42	TTN	Q13557	CAMK2D	S5401	G5399C	5399	Missense	proximal	-2	no	40.655	40.328	EPSD	ICGC;COSMIC	37.605	Down-regulation
CAMK_CAMK2_CAMK2D_ST	Q8WZ42	TTN	Q13557	CAMK2D	S5401	V5407M	5407	Missense	distal	6	no	40.655	38.272	EPSD	ICGC;COSMIC	37.605	Down-regulation
CAMK_CAMK2_CAMK2D_ST	Q8WZ42	TTN	Q13557	CAMK2D	S5401	A5405D	5405	Missense	distal	4	no	40.655	40.664	EPSD	ICGC;COSMIC	37.605	Up-regulation
CAMK_CAMK2_CAMK2D_ST	Q8WZ42	TTN	Q13557	CAMK2D	S5401	S5401G	5401	Missense	central	0	yes	40.655	0.000	EPSD	ICGC;COSMIC	37.605	Loss
CAMK_CAMK2_CAMK2D_ST	Q8WZ42	TTN	Q13557	CAMK2D	S5421	R5426Q	5426	Missense	distal	5	no	35.698	37.718	EPSD	ICGC;COSMIC	37.605	Gain
CAMK_CAMK2_CAMK2D_ST	Q8WZ42	TTN	Q13557	CAMK2D	S5421	T5422S	5422	Missense	proximal	1	no	35.698	38.100	EPSD	ICGC;COSMIC	37.605	Gain
CAMK_CAMK2_CAMK2D_ST	Q8WZ42	TTN	Q13557	CAMK2D	S5421	T5422I	5422	Missense	proximal	1	no	35.698	45.898	EPSD	ICGC	37.605	Gain
CAMK_CAMK2_CAMK2D_ST	Q8WZ42	TTN	Q13557	CAMK2D	T5568	D5572N	5572	Missense	distal	4	no	36.627	38.252	EPSD	ICGC;COSMIC	37.605	Gain
CAMK_CAMK2_CAMK2D_ST	Q8WZ42	TTN	Q13557	CAMK2D	T5568	K5570R	5570	Missense	proximal	2	no	36.627	39.752	EPSD	ICGC;COSMIC	37.605	Gain
CAMK_CAMK2_CAMK2D_ST	Q8WZ42	TTN	Q13557	CAMK2D	S5573	K5570R	5570	Missense	distal	-3	no	27.513	38.921	EPSD	ICGC;COSMIC	37.605	Gain
CAMK_CAMK2_CAMK2D_ST	Q8WZ42	TTN	Q13557	CAMK2D	S5603	T5605A	5605	Missense	proximal	2	no	36.499	41.150	EPSD	ICGC	37.605	Gain
CAMK_CAMK2_CAMK2D_ST	Q8WZ42	TTN	Q13557	CAMK2D	S5603	L5598F	5598	Missense	distal	-5	no	36.499	38.431	EPSD	ICGC;COSMIC	37.605	Gain
CAMK_CAMK2_CAMK2D_ST	Q8WZ42	TTN	Q13557	CAMK2D	S5643	S5643L	5643	Missense	central	0	yes	38.223	0.000	EPSD	ICGC;COSMIC	37.605	Loss
CAMK_CAMK2_CAMK2D_ST	Q8WZ42	TTN	Q13557	CAMK2D	S5643	E5646G	5646	Missense	distal	3	no	38.223	30.308	EPSD	ICGC;COSMIC	37.605	Loss
CAMK_CAMK2_CAMK2D_ST	Q8WZ42	TTN	Q13557	CAMK2D	S5643	K5637N	5637	Missense	distal	-6	no	38.223	47.188	EPSD	ICGC;COSMIC	37.605	Up-regulation
CAMK_CAMK2_CAMK2D_ST	Q8WZ42	TTN	Q13557	CAMK2D	S5643	Q5640H	5640	Missense	distal	-3	no	38.223	12.120	EPSD	ICGC;COSMIC	37.605	Loss
CAMK_CAMK2_CAMK2D_ST	Q8WZ42	TTN	Q13557	CAMK2D	S5643	E5646K	5646	Missense	distal	3	no	38.223	32.203	EPSD	ICGC;COSMIC	37.605	Loss
CAMK_CAMK2_CAMK2D_ST	Q8WZ42	TTN	Q13557	CAMK2D	S5643	E5641K	5641	Missense	proximal	-2	no	38.223	38.460	EPSD	ICGC	37.605	Up-regulation
CAMK_CAMK2_CAMK2D_ST	Q8WZ42	TTN	Q13557	CAMK2D	S5643	I5642L	5642	Missense	proximal	-1	no	38.223	37.592	EPSD	ICGC;COSMIC	37.605	Loss
CAMK_CAMK2_CAMK2D_ST	Q8WZ42	TTN	Q13557	CAMK2D	S5643	A5644S	5644	Missense	proximal	1	no	38.223	42.580	EPSD	ICGC;COSMIC	37.605	Up-regulation
CAMK_CAMK2_CAMK2D_ST	Q8WZ42	TTN	Q13557	CAMK2D	S5643	F5650L	5650	Missense	distal	7	no	38.223	39.458	EPSD	ICGC;COSMIC	37.605	Up-regulation
CAMK_CAMK2_CAMK2D_ST	Q8WZ42	TTN	Q13557	CAMK2D	S5703	V5706A	5706	Missense	distal	3	no	26.699	47.931	EPSD	ICGC	37.605	Gain
CAMK_CAMK2_CAMK2D_ST	Q8WZ42	TTN	Q13557	CAMK2D	S6117	M6116I	6116	Missense	proximal	-1	no	38.941	40.542	EPSD	ICGC;COSMIC	37.605	Up-regulation
CAMK_CAMK2_CAMK2D_ST	Q8WZ42	TTN	Q13557	CAMK2D	S6117	S6117N	6117	Missense	central	0	yes	38.941	0.000	EPSD	ICGC;COSMIC	37.605	Loss
CAMK_CAMK2_CAMK2D_ST	Q8WZ42	TTN	Q13557	CAMK2D	S6117	Y6113H	6113	Missense	distal	-4	no	38.941	37.699	EPSD	ICGC	37.605	Down-regulation
CAMK_CAMK2_CAMK2D_ST	Q8WZ42	TTN	Q13557	CAMK2D	S6117	S6117G	6117	Missense	central	0	yes	38.941	0.000	EPSD	ICGC;COSMIC	37.605	Loss
CAMK_CAMK2_CAMK2D_ST	Q8WZ42	TTN	Q13557	CAMK2D	S6117	N6121S	6121	Missense	distal	4	no	38.941	38.729	EPSD	ICGC	37.605	Down-regulation
CAMK_CAMK2_CAMK2D_ST	Q8WZ42	TTN	Q13557	CAMK2D	S6124	S6129P	6129	Missense	distal	5	no	44.201	47.054	EPSD	ICGC;COSMIC	37.605	Up-regulation
CAMK_CAMK2_CAMK2D_ST	Q8WZ42	TTN	Q13557	CAMK2D	S6124	S6117N	6117	Missense	distal	-7	no	44.201	41.063	EPSD	ICGC;COSMIC	37.605	Down-regulation
CAMK_CAMK2_CAMK2D_ST	Q8WZ42	TTN	Q13557	CAMK2D	S6124	M6131I	6131	Missense	distal	7	no	44.201	44.384	EPSD	ICGC;COSMIC	37.605	Up-regulation
CAMK_CAMK2_CAMK2D_ST	Q8WZ42	TTN	Q13557	CAMK2D	S6124	R6126K	6126	Missense	proximal	2	no	44.201	41.076	EPSD	ICGC	37.605	Down-regulation
CAMK_CAMK2_CAMK2D_ST	Q8WZ42	TTN	Q13557	CAMK2D	S6124	S6117G	6117	Missense	distal	-7	no	44.201	40.833	EPSD	ICGC;COSMIC	37.605	Down-regulation
CAMK_CAMK2_CAMK2D_ST	Q8WZ42	TTN	Q13557	CAMK2D	S6124	N6121S	6121	Missense	distal	-3	no	44.201	47.726	EPSD	ICGC	37.605	Up-regulation
CAMK_CAMK2_CAMK2D_ST	Q8WZ42	TTN	Q13557	CAMK2D	S6165	P6164S	6164	Missense	proximal	-1	no	34.430	37.639	EPSD	ICGC	37.605	Gain
CAMK_CAMK2_CAMK2D_ST	Q8WZ42	TTN	Q13557	CAMK2D	S6205	K6202E	6202	Missense	distal	-3	no	39.253	4.969	EPSD	ICGC;COSMIC	37.605	Loss
CAMK_CAMK2_CAMK2D_ST	Q8WZ42	TTN	Q13557	CAMK2D	S6205	E6203K	6203	Missense	proximal	-2	no	39.253	39.490	EPSD	ICGC;COSMIC	37.605	Up-regulation
CAMK_CAMK2_CAMK2D_ST	Q8WZ42	TTN	Q13557	CAMK2D	S6205	D6200N	6200	Missense	distal	-5	no	39.253	39.295	EPSD	ICGC;COSMIC	37.605	Up-regulation
CAMK_CAMK2_CAMK2D_ST	Q8WZ42	TTN	Q13557	CAMK2D	S6205	R6211K	6211	Missense	distal	6	no	39.253	38.599	EPSD	ICGC;COSMIC	37.605	Down-regulation
CAMK_CAMK2_CAMK2D_ST	Q8WZ42	TTN	Q13557	CAMK2D	S6205	G6201E	6201	Missense	distal	-4	no	39.253	37.075	EPSD	ICGC;COSMIC	37.605	Loss
CAMK_CAMK2_CAMK2D_ST	Q8WZ42	TTN	Q13557	CAMK2D	S6205	T6206K	6206	Missense	proximal	1	no	39.253	42.603	EPSD	ICGC;COSMIC	37.605	Up-regulation
CAMK_CAMK2_CAMK2D_ST	Q8WZ42	TTN	Q13557	CAMK2D	T6332	C6329R	6329	Missense	distal	-3	no	13.868	43.371	EPSD	ICGC;COSMIC	37.605	Gain
CAMK_CAMK2_CAMK2D_ST	Q8WZ42	TTN	Q13557	CAMK2D	T6508	I6503L	6503	Missense	distal	-5	no	38.257	38.188	EPSD	ICGC;COSMIC	37.605	Down-regulation
CAMK_CAMK2_CAMK2D_ST	Q8WZ42	TTN	Q13557	CAMK2D	T6508	Y6514H	6514	Missense	distal	6	no	38.257	40.111	EPSD	ICGC;COSMIC	37.605	Up-regulation
CAMK_CAMK2_CAMK2D_ST	Q8WZ42	TTN	Q13557	CAMK2D	S6692	S6686P	6686	Missense	distal	-6	no	54.175	53.823	EPSD	ICGC	37.605	Down-regulation
CAMK_CAMK2_CAMK2D_ST	Q8WZ42	TTN	Q13557	CAMK2D	S6692	A6698V	6698	Missense	distal	6	no	54.175	52.406	EPSD	ICGC;COSMIC	37.605	Down-regulation
CAMK_CAMK2_CAMK2D_ST	Q8WZ42	TTN	Q13557	CAMK2D	S6692	R6689S	6689	Missense	distal	-3	no	54.175	38.001	EPSD	ICGC;COSMIC	37.605	Down-regulation
CAMK_CAMK2_CAMK2D_ST	Q8WZ42	TTN	Q13557	CAMK2D	S6692	I6685V	6685	Missense	distal	-7	no	54.175	48.756	EPSD	ICGC	37.605	Down-regulation
CAMK_CAMK2_CAMK2D_ST	Q8WZ42	TTN	Q13557	CAMK2D	S6692	R6689K	6689	Missense	distal	-3	no	54.175	42.767	EPSD	ICGC;COSMIC	37.605	Down-regulation
CAMK_CAMK2_CAMK2D_ST	Q8WZ42	TTN	Q13557	CAMK2D	S6728	P6727L	6727	Missense	proximal	-1	no	36.602	38.377	EPSD	ICGC;COSMIC	37.605	Gain
CAMK_CAMK2_CAMK2D_ST	Q8WZ42	TTN	Q13557	CAMK2D	S6728	P6727S	6727	Missense	proximal	-1	no	36.602	39.810	EPSD	ICGC;COSMIC	37.605	Gain
CAMK_CAMK2_CAMK2D_ST	Q8WZ42	TTN	Q13557	CAMK2D	S6923	H6922N	6922	Missense	proximal	-1	no	40.074	42.371	EPSD	ICGC;COSMIC	37.605	Up-regulation
CAMK_CAMK2_CAMK2D_ST	Q8WZ42	TTN	Q13557	CAMK2D	S6923	H6922Y	6922	Missense	proximal	-1	no	40.074	41.900	EPSD	ICGC;COSMIC	37.605	Up-regulation
CAMK_CAMK2_CAMK2D_ST	Q8WZ42	TTN	Q13557	CAMK2D	S6923	G6927R	6927	Missense	distal	4	no	40.074	40.330	EPSD	ICGC;COSMIC	37.605	Up-regulation
CAMK_CAMK2_CAMK2D_ST	Q8WZ42	TTN	Q13557	CAMK2D	S6923	L6919V	6919	Missense	distal	-4	no	40.074	44.138	EPSD	ICGC;COSMIC	37.605	Up-regulation
CAMK_CAMK2_CAMK2D_ST	Q8WZ42	TTN	Q13557	CAMK2D	S6923	R6918I	6918	Missense	distal	-5	no	40.074	40.355	EPSD	ICGC;COSMIC	37.605	Up-regulation
CAMK_CAMK2_CAMK2D_ST	Q8WZ42	TTN	Q13557	CAMK2D	T6954	N6952K	6952	Missense	proximal	-2	no	44.547	44.071	EPSD	ICGC	37.605	Down-regulation
CAMK_CAMK2_CAMK2D_ST	Q8WZ42	TTN	Q13557	CAMK2D	T6954	D6949N	6949	Missense	distal	-5	no	44.547	44.589	EPSD	ICGC;COSMIC	37.605	Up-regulation
CAMK_CAMK2_CAMK2D_ST	Q8WZ42	TTN	Q13557	CAMK2D	T6954	C6959Y	6959	Missense	distal	5	no	44.547	45.273	EPSD	ICGC;COSMIC	37.605	Up-regulation
CAMK_CAMK2_CAMK2D_ST	Q8WZ42	TTN	Q13557	CAMK2D	T6954	N6960D	6960	Missense	distal	6	no	44.547	42.451	EPSD	ICGC	37.605	Down-regulation
CAMK_CAMK2_CAMK2D_ST	Q8WZ42	TTN	Q13557	CAMK2D	T6954	G6950A	6950	Missense	distal	-4	no	44.547	46.210	EPSD	ICGC;COSMIC	37.605	Up-regulation
CAMK_CAMK2_CAMK2D_ST	Q8WZ42	TTN	Q13557	CAMK2D	T6954	E6957G	6957	Missense	distal	3	no	44.547	36.633	EPSD	ICGC	37.605	Loss
CAMK_CAMK2_CAMK2D_ST	Q8WZ42	TTN	Q13557	CAMK2D	S6956	V6962A	6962	Missense	distal	6	no	36.488	38.257	EPSD	ICGC;COSMIC	37.605	Gain
CAMK_CAMK2_CAMK2D_ST	Q8WZ42	TTN	Q13557	CAMK2D	S6956	N6952K	6952	Missense	distal	-4	no	36.488	40.390	EPSD	ICGC	37.605	Gain
CAMK_CAMK2_CAMK2D_ST	Q8WZ42	TTN	Q13557	CAMK2D	S6956	C6959Y	6959	Missense	distal	3	no	36.488	38.897	EPSD	ICGC;COSMIC	37.605	Gain
CAMK_CAMK2_CAMK2D_ST	Q8WZ42	TTN	Q13557	CAMK2D	T7230	D7234H	7234	Missense	distal	4	no	43.087	43.089	EPSD	ICGC;COSMIC	37.605	Up-regulation
CAMK_CAMK2_CAMK2D_ST	Q8WZ42	TTN	Q13557	CAMK2D	T7230	N7235S	7235	Missense	distal	5	no	43.087	42.591	EPSD	ICGC;COSMIC;CCLE	37.605	Down-regulation
CAMK_CAMK2_CAMK2D_ST	Q8WZ42	TTN	Q13557	CAMK2D	T7230	Q7225K	7225	Missense	distal	-5	no	43.087	43.328	EPSD	ICGC	37.605	Up-regulation
CAMK_CAMK2_CAMK2D_ST	Q8WZ42	TTN	Q13557	CAMK2D	T7230	W7231R	7231	Missense	proximal	1	no	43.087	48.604	EPSD	ICGC	37.605	Up-regulation
CAMK_CAMK2_CAMK2D_ST	Q8WZ42	TTN	Q13557	CAMK2D	T7230	K7233N	7233	Missense	distal	3	no	43.087	44.949	EPSD	ICGC;COSMIC	37.605	Up-regulation
CAMK_CAMK2_CAMK2D_ST	Q8WZ42	TTN	Q13557	CAMK2D	T7230	E7237K	7237	Missense	distal	7	no	43.087	43.165	EPSD	ICGC;COSMIC	37.605	Up-regulation
CAMK_CAMK2_CAMK2D_ST	Q8WZ42	TTN	Q13557	CAMK2D	T7230	D7234N	7234	Missense	distal	4	no	43.087	44.711	EPSD	ICGC;COSMIC	37.605	Up-regulation
CAMK_CAMK2_CAMK2D_ST	Q8WZ42	TTN	Q13557	CAMK2D	S7308	A7303T	7303	Missense	distal	-5	no	40.027	38.942	EPSD	ICGC;COSMIC	37.605	Down-regulation
CAMK_CAMK2_CAMK2D_ST	Q8WZ42	TTN	Q13557	CAMK2D	S7308	E7307G	7307	Missense	proximal	-1	no	40.027	39.881	EPSD	ICGC;COSMIC	37.605	Down-regulation
CAMK_CAMK2_CAMK2D_ST	Q8WZ42	TTN	Q13557	CAMK2D	S7308	A7303S	7303	Missense	distal	-5	no	40.027	38.451	EPSD	ICGC;COSMIC	37.605	Down-regulation
CAMK_CAMK2_CAMK2D_ST	Q8WZ42	TTN	Q13557	CAMK2D	S7308	A7303V	7303	Missense	distal	-5	no	40.027	39.195	EPSD	ICGC;COSMIC	37.605	Down-regulation
CAMK_CAMK2_CAMK2D_ST	Q8WZ42	TTN	Q13557	CAMK2D	S7308	G7306V	7306	Missense	proximal	-2	no	40.027	40.128	EPSD	ICGC;COSMIC	37.605	Up-regulation
CAMK_CAMK2_CAMK2D_ST	Q8WZ42	TTN	Q13557	CAMK2D	S7308	I7315T	7315	Missense	distal	7	no	40.027	40.621	EPSD	ICGC;COSMIC	37.605	Up-regulation
CAMK_CAMK2_CAMK2D_ST	Q8WZ42	TTN	Q13557	CAMK2D	S7330	H7333R	7333	Missense	distal	3	no	32.580	42.127	EPSD	ICGC;COSMIC	37.605	Gain
CAMK_CAMK2_CAMK2D_ST	Q8WZ42	TTN	Q13557	CAMK2D	S7335	L7332R	7332	Missense	distal	-3	no	23.210	45.046	EPSD	ICGC	37.605	Gain
CAMK_CAMK2_CAMK2D_ST	Q8WZ42	TTN	Q13557	CAMK2D	S7613	R7610K	7610	Missense	distal	-3	no	45.107	33.699	EPSD	ICGC;COSMIC	37.605	Loss
CAMK_CAMK2_CAMK2D_ST	Q8WZ42	TTN	Q13557	CAMK2D	S7613	H7618Y	7618	Missense	distal	5	no	45.107	44.129	EPSD	ICGC	37.605	Down-regulation
CAMK_CAMK2_CAMK2D_ST	Q8WZ42	TTN	Q13557	CAMK2D	S7613	I7620V	7620	Missense	distal	7	no	45.107	44.850	EPSD	ICGC;COSMIC	37.605	Down-regulation
CAMK_CAMK2_CAMK2D_ST	Q8WZ42	TTN	Q13557	CAMK2D	S7613	R7610T	7610	Missense	distal	-3	no	45.107	23.476	EPSD	ICGC;COSMIC	37.605	Loss
CAMK_CAMK2_CAMK2D_ST	Q8WZ42	TTN	Q13557	CAMK2D	S7613	G7609R	7609	Missense	distal	-4	no	45.107	47.407	EPSD	ICGC;COSMIC	37.605	Up-regulation
CAMK_CAMK2_CAMK2D_ST	Q8WZ42	TTN	Q13557	CAMK2D	S7613	F7606L	7606	Missense	distal	-7	no	45.107	51.111	EPSD	ICGC;COSMIC;CCLE	37.605	Up-regulation
CAMK_CAMK2_CAMK2D_ST	Q8WZ42	TTN	Q13557	CAMK2D	S7649	V7650A	7650	Missense	proximal	1	no	38.831	32.399	EPSD	ICGC	37.605	Loss
CAMK_CAMK2_CAMK2D_ST	Q8WZ42	TTN	Q13557	CAMK2D	S7684	L7681R	7681	Missense	distal	-3	no	26.035	47.871	EPSD	ICGC	37.605	Gain
CAMK_CAMK2_CAMK2D_ST	Q8WZ42	TTN	Q13557	CAMK2D	S7989	A7992T	7992	Missense	distal	3	no	51.310	38.183	EPSD	ICGC;COSMIC	37.605	Down-regulation
CAMK_CAMK2_CAMK2D_ST	Q8WZ42	TTN	Q13557	CAMK2D	S7989	P7991T	7991	Missense	proximal	2	no	51.310	50.459	EPSD	ICGC;COSMIC	37.605	Down-regulation
CAMK_CAMK2_CAMK2D_ST	Q8WZ42	TTN	Q13557	CAMK2D	S7989	Y7993H	7993	Missense	distal	4	no	51.310	50.297	EPSD	ICGC;COSMIC	37.605	Down-regulation
CAMK_CAMK2_CAMK2D_ST	Q8WZ42	TTN	Q13557	CAMK2D	S7989	R7988Q	7988	Missense	proximal	-1	no	51.310	48.407	EPSD	ICGC;COSMIC	37.605	Down-regulation
CAMK_CAMK2_CAMK2D_ST	Q8WZ42	TTN	Q13557	CAMK2D	S7989	M7995I	7995	Missense	distal	6	no	51.310	51.944	EPSD	ICGC;COSMIC	37.605	Up-regulation
CAMK_CAMK2_CAMK2D_ST	Q8WZ42	TTN	Q13557	CAMK2D	S7989	E7983K	7983	Missense	distal	-6	no	51.310	49.327	EPSD	ICGC;COSMIC	37.605	Down-regulation
CAMK_CAMK2_CAMK2D_ST	Q8WZ42	TTN	Q13557	CAMK2D	S8426	L8425F	8425	Missense	proximal	-1	no	40.779	38.940	EPSD	ICGC;COSMIC	37.605	Down-regulation
CAMK_CAMK2_CAMK2D_ST	Q8WZ42	TTN	Q13557	CAMK2D	S8426	S8429Y	8429	Missense	distal	3	no	40.779	44.225	EPSD	ICGC;COSMIC	37.605	Up-regulation
CAMK_CAMK2_CAMK2D_ST	Q8WZ42	TTN	Q13557	CAMK2D	S8426	K8424N	8424	Missense	proximal	-2	no	40.779	41.255	EPSD	ICGC;COSMIC	37.605	Up-regulation
CAMK_CAMK2_CAMK2D_ST	Q8WZ42	TTN	Q13557	CAMK2D	S8426	D8427E	8427	Missense	proximal	1	no	40.779	44.706	EPSD	ICGC	37.605	Up-regulation
CAMK_CAMK2_CAMK2D_ST	Q8WZ42	TTN	Q13557	CAMK2D	S8426	S8429C	8429	Missense	distal	3	no	40.779	41.815	EPSD	ICGC;COSMIC	37.605	Up-regulation
CAMK_CAMK2_CAMK2D_ST	Q8WZ42	TTN	Q13557	CAMK2D	S8426	K8424Q	8424	Missense	proximal	-2	no	40.779	41.010	EPSD	ICGC;COSMIC	37.605	Up-regulation
CAMK_CAMK2_CAMK2D_ST	Q8WZ42	TTN	Q13557	CAMK2D	S8426	S8429F	8429	Missense	distal	3	no	40.779	34.956	EPSD	ICGC	37.605	Loss
CAMK_CAMK2_CAMK2D_ST	Q8WZ42	TTN	Q13557	CAMK2D	S8426	S8426I	8426	Missense	central	0	yes	40.779	0.000	EPSD	ICGC;COSMIC	37.605	Loss
CAMK_CAMK2_CAMK2D_ST	Q8WZ42	TTN	Q13557	CAMK2D	S8740	V8743L	8743	Missense	distal	3	no	40.516	45.394	EPSD	ICGC;COSMIC	37.605	Up-regulation
CAMK_CAMK2_CAMK2D_ST	Q8WZ42	TTN	Q13557	CAMK2D	S8740	P8744T	8744	Missense	distal	4	no	40.516	39.410	EPSD	ICGC;COSMIC;CCLE	37.605	Down-regulation
CAMK_CAMK2_CAMK2D_ST	Q8WZ42	TTN	Q13557	CAMK2D	S8740	E8741D	8741	Missense	proximal	1	no	40.516	36.589	EPSD	ICGC;COSMIC	37.605	Loss
CAMK_CAMK2_CAMK2D_ST	Q8WZ42	TTN	Q13557	CAMK2D	S8740	G8738S	8738	Missense	proximal	-2	no	40.516	40.701	EPSD	ICGC	37.605	Up-regulation
CAMK_CAMK2_CAMK2D_ST	Q8WZ42	TTN	Q13557	CAMK2D	S8740	S8734N	8734	Missense	distal	-6	no	40.516	50.169	EPSD	ICGC	37.605	Up-regulation
CAMK_CAMK2_CAMK2D_ST	Q8WZ42	TTN	Q13557	CAMK2D	S8805	S8805R	8805	Missense	central	0	yes	38.996	0.000	EPSD	ICGC;COSMIC	37.605	Loss
CAMK_CAMK2_CAMK2D_ST	Q8WZ42	TTN	Q13557	CAMK2D	S8805	I8806M	8806	Missense	proximal	1	no	38.996	38.147	EPSD	ICGC;COSMIC	37.605	Down-regulation
CAMK_CAMK2_CAMK2D_ST	Q8WZ42	TTN	Q13557	CAMK2D	S8805	E8807K	8807	Missense	proximal	2	no	38.996	34.679	EPSD	ICGC	37.605	Loss
CAMK_CAMK2_CAMK2D_ST	Q8WZ42	TTN	Q13557	CAMK2D	S8805	G8809E	8809	Missense	distal	4	no	38.996	39.262	EPSD	ICGC;COSMIC	37.605	Up-regulation
CAMK_CAMK2_CAMK2D_ST	Q8WZ42	TTN	Q13557	CAMK2D	S8805	L8812R	8812	Missense	distal	7	no	38.996	37.269	EPSD	ICGC	37.605	Loss
CAMK_CAMK2_CAMK2D_ST	Q8WZ42	TTN	Q13557	CAMK2D	S8805	E8807D	8807	Missense	proximal	2	no	38.996	46.422	EPSD	ICGC;COSMIC	37.605	Up-regulation
CAMK_CAMK2_CAMK2D_ST	Q8WZ42	TTN	Q13557	CAMK2D	S8805	S8805I	8805	Missense	central	0	yes	38.996	0.000	EPSD	ICGC;COSMIC	37.605	Loss
CAMK_CAMK2_CAMK2D_ST	Q8WZ42	TTN	Q13557	CAMK2D	T8836	P8837S	8837	Missense	proximal	1	no	37.043	40.676	EPSD	ICGC	37.605	Gain
CAMK_CAMK2_CAMK2D_ST	Q8WZ42	TTN	Q13557	CAMK2D	S9177	S9177R	9177	Missense	central	0	yes	38.500	0.000	EPSD	ICGC;COSMIC	37.605	Loss
CAMK_CAMK2_CAMK2D_ST	Q8WZ42	TTN	Q13557	CAMK2D	S9177	R9181T	9181	Missense	distal	4	no	38.500	37.461	EPSD	ICGC;COSMIC;CCLE	37.605	Loss
CAMK_CAMK2_CAMK2D_ST	Q8WZ42	TTN	Q13557	CAMK2D	S9177	P9175Q	9175	Missense	proximal	-2	no	38.500	38.416	EPSD	ICGC;COSMIC	37.605	Down-regulation
CAMK_CAMK2_CAMK2D_ST	Q8WZ42	TTN	Q13557	CAMK2D	T9189	E9187K	9187	Missense	proximal	-2	no	43.771	44.009	EPSD	ICGC;COSMIC	37.605	Up-regulation
CAMK_CAMK2_CAMK2D_ST	Q8WZ42	TTN	Q13557	CAMK2D	T9189	T9185A	9185	Missense	distal	-4	no	43.771	43.355	EPSD	ICGC;COSMIC	37.605	Down-regulation
CAMK_CAMK2_CAMK2D_ST	Q8WZ42	TTN	Q13557	CAMK2D	T9189	S9193T	9193	Missense	distal	4	no	43.771	42.893	EPSD	ICGC;COSMIC	37.605	Down-regulation
CAMK_CAMK2_CAMK2D_ST	Q8WZ42	TTN	Q13557	CAMK2D	T9189	G9191E	9191	Missense	proximal	2	no	43.771	42.076	EPSD	ICGC;COSMIC	37.605	Down-regulation
CAMK_CAMK2_CAMK2D_ST	Q8WZ42	TTN	Q13557	CAMK2D	S9633	I9634T	9634	Missense	proximal	1	no	39.074	28.874	EPSD	ICGC;COSMIC	37.605	Loss
CAMK_CAMK2_CAMK2D_ST	Q8WZ42	TTN	Q13557	CAMK2D	S9633	R9638Q	9638	Missense	distal	5	no	39.074	41.094	EPSD	ICGC;COSMIC	37.605	Up-regulation
CAMK_CAMK2_CAMK2D_ST	Q8WZ42	TTN	Q13557	CAMK2D	S9633	F9630C	9630	Missense	distal	-3	no	39.074	24.558	EPSD	ICGC;COSMIC	37.605	Loss
CAMK_CAMK2_CAMK2D_ST	Q8WZ42	TTN	Q13557	CAMK2D	S9633	P9626S	9626	Missense	distal	-7	no	39.074	42.325	EPSD	ICGC;COSMIC	37.605	Up-regulation
CAMK_CAMK2_CAMK2D_ST	Q8WZ42	TTN	Q13557	CAMK2D	T10388	K10393N	10393	Missense	distal	5	no	37.511	38.034	EPSD	ICGC;COSMIC;CCLE	37.605	Gain
CAMK_CAMK2_CAMK2D_ST	Q8WZ42	TTN	Q13557	CAMK2D	T10388	K10393R	10393	Missense	distal	5	no	37.511	37.957	EPSD	ICGC;COSMIC	37.605	Gain
CAMK_CAMK2_CAMK2D_ST	Q8WZ42	TTN	Q13557	CAMK2D	T10581	L10577I	10577	Missense	distal	-4	no	53.675	55.349	EPSD	ICGC;COSMIC	37.605	Up-regulation
CAMK_CAMK2_CAMK2D_ST	Q8WZ42	TTN	Q13557	CAMK2D	T10581	K10588N	10588	Missense	distal	7	no	53.675	53.216	EPSD	ICGC	37.605	Down-regulation
CAMK_CAMK2_CAMK2D_ST	Q8WZ42	TTN	Q13557	CAMK2D	T10581	V10578A	10578	Missense	distal	-3	no	53.675	40.103	EPSD	ICGC;COSMIC	37.605	Down-regulation
CAMK_CAMK2_CAMK2D_ST	Q8WZ42	TTN	Q13557	CAMK2D	T10581	K10575N	10575	Missense	distal	-6	no	53.675	62.641	EPSD	ICGC;COSMIC	37.605	Up-regulation
CAMK_CAMK2_CAMK2D_ST	Q8WZ42	TTN	Q13557	CAMK2D	T10581	E10584D	10584	Missense	distal	3	no	53.675	41.090	EPSD	ICGC;COSMIC	37.605	Down-regulation
CAMK_CAMK2_CAMK2D_ST	Q8WZ42	TTN	Q13557	CAMK2D	T10581	A10579V	10579	Missense	proximal	-2	no	53.675	53.949	EPSD	ICGC;COSMIC	37.605	Up-regulation
CAMK_CAMK2_CAMK2D_ST	Q8WZ42	TTN	Q13557	CAMK2D	T10581	T10581I	10581	Missense	central	0	yes	53.675	0.000	EPSD	ICGC;COSMIC	37.605	Loss
CAMK_CAMK2_CAMK2D_ST	Q8WZ42	TTN	Q13557	CAMK2D	T10581	T10581N	10581	Missense	central	0	yes	53.675	0.000	EPSD	ICGC	37.605	Loss
CAMK_CAMK2_CAMK2D_ST	Q8WZ42	TTN	Q13557	CAMK2D	T10581	A10585V	10585	Missense	distal	4	no	53.675	53.034	EPSD	ICGC;COSMIC	37.605	Down-regulation
CAMK_CAMK2_CAMK2D_ST	Q8WZ42	TTN	Q13557	CAMK2D	T10581	K10575E	10575	Missense	distal	-6	no	53.675	55.659	EPSD	ICGC	37.605	Up-regulation
CAMK_CAMK2_CAMK2D_ST	Q8WZ42	TTN	Q13557	CAMK2D	T10658	E10660Q	10660	Missense	proximal	2	no	53.104	52.665	EPSD	ICGC	37.605	Down-regulation
CAMK_CAMK2_CAMK2D_ST	Q8WZ42	TTN	Q13557	CAMK2D	T10658	T10658N	10658	Missense	central	0	yes	53.104	0.000	EPSD	ICGC	37.605	Loss
CAMK_CAMK2_CAMK2D_ST	Q8WZ42	TTN	Q13557	CAMK2D	T10658	E10662A	10662	Missense	distal	4	no	53.104	51.510	EPSD	ICGC;COSMIC	37.605	Down-regulation
CAMK_CAMK2_CAMK2D_ST	Q8WZ42	TTN	Q13557	CAMK2D	T10658	R10655K	10655	Missense	distal	-3	no	53.104	41.697	EPSD	ICGC	37.605	Down-regulation
CAMK_CAMK2_CAMK2D_ST	Q8WZ42	TTN	Q13557	CAMK2D	T10658	A10663V	10663	Missense	distal	5	no	53.104	52.892	EPSD	ICGC;COSMIC	37.605	Down-regulation
CAMK_CAMK2_CAMK2D_ST	Q8WZ42	TTN	Q13557	CAMK2D	T10658	S10665L	10665	Missense	distal	7	no	53.104	54.989	EPSD	ICGC;COSMIC	37.605	Up-regulation
CAMK_CAMK2_CAMK2D_ST	Q8WZ42	TTN	Q13557	CAMK2D	T10658	E10651K	10651	Missense	distal	-7	no	53.104	59.372	EPSD	ICGC;COSMIC	37.605	Up-regulation
CAMK_CAMK2_CAMK2D_ST	Q8WZ42	TTN	Q13557	CAMK2D	T10658	Y10657D	10657	Missense	proximal	-1	no	53.104	51.590	EPSD	ICGC;COSMIC	37.605	Down-regulation
CAMK_CAMK2_CAMK2D_ST	Q8WZ42	TTN	Q13557	CAMK2D	T10658	E10652D	10652	Missense	distal	-6	no	53.104	46.925	EPSD	ICGC;COSMIC	37.605	Down-regulation
CAMK_CAMK2_CAMK2D_ST	Q8WZ42	TTN	Q13557	CAMK2D	S10781	T10783A	10783	Missense	proximal	2	no	39.141	43.792	EPSD	ICGC;COSMIC	37.605	Up-regulation
CAMK_CAMK2_CAMK2D_ST	Q8WZ42	TTN	Q13557	CAMK2D	S10781	I10780T	10780	Missense	proximal	-1	no	39.141	40.102	EPSD	ICGC;COSMIC	37.605	Up-regulation
CAMK_CAMK2_CAMK2D_ST	Q8WZ42	TTN	Q13557	CAMK2D	S10781	E10788Q	10788	Missense	distal	7	no	39.141	37.994	EPSD	ICGC;COSMIC	37.605	Down-regulation
CAMK_CAMK2_CAMK2D_ST	Q8WZ42	TTN	Q13557	CAMK2D	S10781	R10779C	10779	Missense	proximal	-2	no	39.141	38.097	EPSD	ICGC;COSMIC	37.605	Down-regulation
CAMK_CAMK2_CAMK2D_ST	Q8WZ42	TTN	Q13557	CAMK2D	S10781	E10776D	10776	Missense	distal	-5	no	39.141	39.601	EPSD	ICGC	37.605	Up-regulation
CAMK_CAMK2_CAMK2D_ST	Q8WZ42	TTN	Q13557	CAMK2D	S10781	E10786K	10786	Missense	distal	5	no	39.141	39.592	EPSD	ICGC;COSMIC	37.605	Up-regulation
CAMK_CAMK2_CAMK2D_ST	Q8WZ42	TTN	Q13557	CAMK2D	S10781	E10788K	10788	Missense	distal	7	no	39.141	39.220	EPSD	ICGC	37.605	Up-regulation
CAMK_CAMK2_CAMK2D_ST	Q8WZ42	TTN	Q13557	CAMK2D	S10781	E10776K	10776	Missense	distal	-5	no	39.141	37.965	EPSD	ICGC;COSMIC	37.605	Down-regulation
CAMK_CAMK2_CAMK2D_ST	Q8WZ42	TTN	Q13557	CAMK2D	S10781	K10784E	10784	Missense	distal	3	no	39.141	45.160	EPSD	ICGC	37.605	Up-regulation
CAMK_CAMK2_CAMK2D_ST	Q8WZ42	TTN	Q13557	CAMK2D	T10791	E10788Q	10788	Missense	distal	-3	no	18.540	53.008	EPSD	ICGC;COSMIC	37.605	Gain
CAMK_CAMK2_CAMK2D_ST	Q8WZ42	TTN	Q13557	CAMK2D	T10791	E10788K	10788	Missense	distal	-3	no	18.540	52.823	EPSD	ICGC	37.605	Gain
CAMK_CAMK2_CAMK2D_ST	Q8WZ42	TTN	Q13557	CAMK2D	S11503	P11499T	11499	Missense	distal	-4	no	48.031	49.497	EPSD	ICGC	37.605	Up-regulation
CAMK_CAMK2_CAMK2D_ST	Q8WZ42	TTN	Q13557	CAMK2D	S11503	E11510D	11510	Missense	distal	7	no	48.031	48.381	EPSD	ICGC	37.605	Up-regulation
CAMK_CAMK2_CAMK2D_ST	Q8WZ42	TTN	Q13557	CAMK2D	S11878	E11873D	11873	Missense	distal	-5	no	73.026	73.486	EPSD;PhosphoSitePlus	ICGC;COSMIC	37.605	Up-regulation
CAMK_CAMK2_CAMK2D_ST	Q8WZ42	TTN	Q13557	CAMK2D	S11878	L11880I	11880	Missense	proximal	2	no	73.026	72.399	EPSD;PhosphoSitePlus	ICGC;COSMIC	37.605	Down-regulation
CAMK_CAMK2_CAMK2D_ST	Q8WZ42	TTN	Q13557	CAMK2D	S11878	E11872K	11872	Missense	distal	-6	no	73.026	71.043	EPSD;PhosphoSitePlus	ICGC;COSMIC	37.605	Down-regulation
CAMK_CAMK2_CAMK2D_ST	Q8WZ42	TTN	Q13557	CAMK2D	S11878	K11871N	11871	Missense	distal	-7	no	73.026	66.240	EPSD;PhosphoSitePlus	ICGC;COSMIC	37.605	Down-regulation
CAMK_CAMK2_CAMK2D_ST	Q8WZ42	TTN	Q13557	CAMK2D	S11878	P11884H	11884	Missense	distal	6	no	73.026	68.646	EPSD;PhosphoSitePlus	ICGC	37.605	Down-regulation
CAMK_CAMK2_CAMK2D_ST	Q8WZ42	TTN	Q13557	CAMK2D	S12022	G12021E	12021	Missense	proximal	-1	no	75.535	75.681	PhosphoSitePlus;EPSD	ICGC;COSMIC	37.605	Up-regulation
CAMK_CAMK2_CAMK2D_ST	Q8WZ42	TTN	Q13557	CAMK2D	S12022	P12027H	12027	Missense	distal	5	no	75.535	73.903	PhosphoSitePlus;EPSD	ICGC;COSMIC	37.605	Down-regulation
CAMK_CAMK2_CAMK2D_ST	Q8WZ42	TTN	Q13557	CAMK2D	S12022	P12027T	12027	Missense	distal	5	no	75.535	73.788	PhosphoSitePlus;EPSD	ICGC;COSMIC	37.605	Down-regulation
CAMK_CAMK2_CAMK2D_ST	Q8WZ42	TTN	Q13557	CAMK2D	T12672	K12666N	12666	Missense	distal	-6	no	30.686	39.652	EPSD	ICGC;COSMIC	37.605	Gain
CAMK_CAMK2_CAMK2D_ST	Q8WZ42	TTN	Q13557	CAMK2D	S12902	S12900L	12900	Missense	proximal	-2	no	53.372	52.996	EPSD	ICGC;COSMIC	37.605	Down-regulation
CAMK_CAMK2_CAMK2D_ST	Q8WZ42	TTN	Q13557	CAMK2D	S12902	E12906K	12906	Missense	distal	4	no	53.372	53.827	EPSD	ICGC;COSMIC	37.605	Up-regulation
CAMK_CAMK2_CAMK2D_ST	Q8WZ42	TTN	Q13557	CAMK2D	S12902	G12907E	12907	Missense	distal	5	no	53.372	51.944	EPSD	ICGC;COSMIC	37.605	Down-regulation
CAMK_CAMK2_CAMK2D_ST	Q8WZ42	TTN	Q13557	CAMK2D	S12911	D12916N	12916	Missense	distal	5	no	37.323	39.404	EPSD	ICGC;COSMIC	37.605	Gain
CAMK_CAMK2_CAMK2D_ST	Q8WZ42	TTN	Q13557	CAMK2D	S12918	D12921Y	12921	Missense	distal	3	no	29.312	42.295	EPSD	ICGC;COSMIC	37.605	Gain
CAMK_CAMK2_CAMK2D_ST	Q8WZ42	TTN	Q13557	CAMK2D	S13172	D13166N	13166	Missense	distal	-6	no	25.756	38.918	EPSD	ICGC;COSMIC	37.605	Gain
CAMK_CAMK2_CAMK2D_ST	Q8WZ42	TTN	Q13557	CAMK2D	T13178	L13181R	13181	Missense	distal	3	no	31.921	40.156	EPSD	ICGC	37.605	Gain
CAMK_CAMK2_CAMK2D_ST	Q8WZ42	TTN	Q13557	CAMK2D	S13501	E13497K	13497	Missense	distal	-4	no	34.817	38.072	EPSD	ICGC;COSMIC	37.605	Gain
CAMK_CAMK2_CAMK2D_ST	Q8WZ42	TTN	Q13557	CAMK2D	T13679	R13686C	13686	Missense	distal	7	no	38.589	40.409	EPSD	ICGC;COSMIC	37.605	Up-regulation
CAMK_CAMK2_CAMK2D_ST	Q8WZ42	TTN	Q13557	CAMK2D	T13679	K13676Q	13676	Missense	distal	-3	no	38.589	38.774	EPSD	ICGC;COSMIC	37.605	Up-regulation
CAMK_CAMK2_CAMK2D_ST	Q8WZ42	TTN	Q13557	CAMK2D	T13679	W13681R	13681	Missense	proximal	2	no	38.589	39.682	EPSD	ICGC	37.605	Up-regulation
CAMK_CAMK2_CAMK2D_ST	Q8WZ42	TTN	Q13557	CAMK2D	T13679	K13675T	13675	Missense	distal	-4	no	38.589	39.591	EPSD	ICGC;COSMIC	37.605	Up-regulation
CAMK_CAMK2_CAMK2D_ST	Q8WZ42	TTN	Q13557	CAMK2D	T13679	S13677F	13677	Missense	proximal	-2	no	38.589	38.346	EPSD	ICGC	37.605	Down-regulation
CAMK_CAMK2_CAMK2D_ST	Q8WZ42	TTN	Q13557	CAMK2D	T13679	E13674V	13674	Missense	distal	-5	no	38.589	39.080	EPSD	ICGC;COSMIC	37.605	Up-regulation
CAMK_CAMK2_CAMK2D_ST	Q8WZ42	TTN	Q13557	CAMK2D	T13679	K13675N	13675	Missense	distal	-4	no	38.589	34.686	EPSD	ICGC	37.605	Loss
CAMK_CAMK2_CAMK2D_ST	Q8WZ42	TTN	Q13557	CAMK2D	S13802	R13805K	13805	Missense	distal	3	no	38.601	37.285	EPSD	ICGC;COSMIC	37.605	Loss
CAMK_CAMK2_CAMK2D_ST	Q8WZ42	TTN	Q13557	CAMK2D	S13802	H13804Q	13804	Missense	proximal	2	no	38.601	42.310	EPSD	ICGC	37.605	Up-regulation
CAMK_CAMK2_CAMK2D_ST	Q8WZ42	TTN	Q13557	CAMK2D	S13802	D13800N	13800	Missense	proximal	-2	no	38.601	39.308	EPSD	ICGC;COSMIC	37.605	Up-regulation
CAMK_CAMK2_CAMK2D_ST	Q8WZ42	TTN	Q13557	CAMK2D	S13802	E13798K	13798	Missense	distal	-4	no	38.601	41.855	EPSD	ICGC;COSMIC	37.605	Up-regulation
CAMK_CAMK2_CAMK2D_ST	Q8WZ42	TTN	Q13557	CAMK2D	S13802	K13809E	13809	Missense	distal	7	no	38.601	38.522	EPSD	ICGC;COSMIC	37.605	Down-regulation
CAMK_CAMK2_CAMK2D_ST	Q8WZ42	TTN	Q13557	CAMK2D	T14099	G14098A	14098	Missense	proximal	-1	no	44.513	43.820	EPSD	ICGC	37.605	Down-regulation
CAMK_CAMK2_CAMK2D_ST	Q8WZ42	TTN	Q13557	CAMK2D	T14099	E14104Q	14104	Missense	distal	5	no	44.513	47.430	EPSD	ICGC;COSMIC	37.605	Up-regulation
CAMK_CAMK2_CAMK2D_ST	Q8WZ42	TTN	Q13557	CAMK2D	T14099	G14098R	14098	Missense	proximal	-1	no	44.513	46.469	EPSD	ICGC;COSMIC	37.605	Up-regulation
CAMK_CAMK2_CAMK2D_ST	Q8WZ42	TTN	Q13557	CAMK2D	T14099	V14097L	14097	Missense	proximal	-2	no	44.513	44.222	EPSD	ICGC;COSMIC	37.605	Down-regulation
CAMK_CAMK2_CAMK2D_ST	Q8WZ42	TTN	Q13557	CAMK2D	T14281	G14282R	14282	Missense	proximal	1	no	35.339	40.094	EPSD	ICGC	37.605	Gain
CAMK_CAMK2_CAMK2D_ST	Q8WZ42	TTN	Q13557	CAMK2D	S14345	P14338R	14338	Missense	distal	-7	no	35.590	40.900	EPSD	ICGC;COSMIC	37.605	Gain
CAMK_CAMK2_CAMK2D_ST	Q8WZ42	TTN	Q13557	CAMK2D	S14345	P14338L	14338	Missense	distal	-7	no	35.590	42.181	EPSD	ICGC	37.605	Gain
CAMK_CAMK2_CAMK2D_ST	Q8WZ42	TTN	Q13557	CAMK2D	S14384	I14381M	14381	Missense	distal	-3	no	35.821	38.560	EPSD	ICGC	37.605	Gain
CAMK_CAMK2_CAMK2D_ST	Q8WZ42	TTN	Q13557	CAMK2D	T14460	R14454P	14454	Missense	distal	-6	no	40.213	36.764	EPSD	ICGC;COSMIC	37.605	Loss
CAMK_CAMK2_CAMK2D_ST	Q8WZ42	TTN	Q13557	CAMK2D	T14460	R14454Q	14454	Missense	distal	-6	no	40.213	43.076	EPSD	ICGC;COSMIC	37.605	Up-regulation
CAMK_CAMK2_CAMK2D_ST	Q8WZ42	TTN	Q13557	CAMK2D	T14460	K14463T	14463	Missense	distal	3	no	40.213	36.521	EPSD	ICGC;COSMIC	37.605	Loss
CAMK_CAMK2_CAMK2D_ST	Q8WZ42	TTN	Q13557	CAMK2D	T14460	M14465I	14465	Missense	distal	5	no	40.213	42.306	EPSD	ICGC;COSMIC	37.605	Up-regulation
CAMK_CAMK2_CAMK2D_ST	Q8WZ42	TTN	Q13557	CAMK2D	T14460	E14455D	14455	Missense	distal	-5	no	40.213	40.673	EPSD	ICGC;COSMIC;CCLE	37.605	Up-regulation
CAMK_CAMK2_CAMK2D_ST	Q8WZ42	TTN	Q13557	CAMK2D	T14633	G14632V	14632	Missense	proximal	-1	no	39.528	40.093	EPSD	ICGC;COSMIC	37.605	Up-regulation
CAMK_CAMK2_CAMK2D_ST	Q8WZ42	TTN	Q13557	CAMK2D	T14633	G14632W	14632	Missense	proximal	-1	no	39.528	37.419	EPSD	ICGC;COSMIC	37.605	Loss
CAMK_CAMK2_CAMK2D_ST	Q8WZ42	TTN	Q13557	CAMK2D	T14674	V14675A	14675	Missense	proximal	1	no	37.612	31.180	EPSD	ICGC;COSMIC	37.605	Loss
CAMK_CAMK2_CAMK2D_ST	Q8WZ42	TTN	Q13557	CAMK2D	T14674	P14670F	14670	Missense	distal	-4	no	37.612	34.796	EPSD	ICGC	37.605	Loss
CAMK_CAMK2_CAMK2D_ST	Q8WZ42	TTN	Q13557	CAMK2D	T14674	P14670S	14670	Missense	distal	-4	no	37.612	37.052	EPSD	ICGC	37.605	Loss
CAMK_CAMK2_CAMK2D_ST	Q8WZ42	TTN	Q13557	CAMK2D	T14674	P14670L	14670	Missense	distal	-4	no	37.612	36.049	EPSD	ICGC	37.605	Loss
CAMK_CAMK2_CAMK2D_ST	Q8WZ42	TTN	Q13557	CAMK2D	T14674	V14669D	14669	Missense	distal	-5	no	37.612	37.580	EPSD	ICGC;COSMIC	37.605	Loss
CAMK_CAMK2_CAMK2D_ST	Q8WZ42	TTN	Q13557	CAMK2D	S14680	V14675A	14675	Missense	distal	-5	no	48.343	49.175	EPSD	ICGC;COSMIC	37.605	Up-regulation
CAMK_CAMK2_CAMK2D_ST	Q8WZ42	TTN	Q13557	CAMK2D	S14680	G14686D	14686	Missense	distal	6	no	48.343	46.019	EPSD	ICGC;COSMIC	37.605	Down-regulation
CAMK_CAMK2_CAMK2D_ST	Q8WZ42	TTN	Q13557	CAMK2D	S14680	D14684E	14684	Missense	distal	4	no	48.343	49.928	EPSD	ICGC	37.605	Up-regulation
CAMK_CAMK2_CAMK2D_ST	Q8WZ42	TTN	Q13557	CAMK2D	S14680	T14687P	14687	Missense	distal	7	no	48.343	47.214	EPSD	ICGC	37.605	Down-regulation
CAMK_CAMK2_CAMK2D_ST	Q8WZ42	TTN	Q13557	CAMK2D	T14925	V14919E	14919	Missense	distal	-6	no	33.711	40.509	EPSD	ICGC	37.605	Gain
CAMK_CAMK2_CAMK2D_ST	Q8WZ42	TTN	Q13557	CAMK2D	T14925	V14927G	14927	Missense	proximal	2	no	33.711	40.286	EPSD	ICGC;COSMIC	37.605	Gain
CAMK_CAMK2_CAMK2D_ST	Q8WZ42	TTN	Q13557	CAMK2D	T14925	D14921Y	14921	Missense	distal	-4	no	33.711	38.106	EPSD	ICGC;COSMIC	37.605	Gain
CAMK_CAMK2_CAMK2D_ST	Q8WZ42	TTN	Q13557	CAMK2D	S15263	E15256K	15256	Missense	distal	-7	no	38.902	45.169	EPSD	ICGC;COSMIC	37.605	Up-regulation
CAMK_CAMK2_CAMK2D_ST	Q8WZ42	TTN	Q13557	CAMK2D	T15466	P15472T	15472	Missense	distal	6	no	37.701	31.169	EPSD	ICGC;COSMIC	37.605	Loss
CAMK_CAMK2_CAMK2D_ST	Q8WZ42	TTN	Q13557	CAMK2D	T15466	D15469N	15469	Missense	distal	3	no	37.701	46.129	EPSD	ICGC;COSMIC	37.605	Up-regulation
CAMK_CAMK2_CAMK2D_ST	Q8WZ42	TTN	Q13557	CAMK2D	T15466	K15468N	15468	Missense	proximal	2	no	37.701	38.019	EPSD	ICGC;COSMIC	37.605	Up-regulation
CAMK_CAMK2_CAMK2D_ST	Q8WZ42	TTN	Q13557	CAMK2D	S15682	N15685K	15685	Missense	distal	3	no	41.614	39.752	EPSD	ICGC;COSMIC	37.605	Down-regulation
CAMK_CAMK2_CAMK2D_ST	Q8WZ42	TTN	Q13557	CAMK2D	S15682	P15676T	15676	Missense	distal	-6	no	41.614	38.994	EPSD	ICGC	37.605	Down-regulation
CAMK_CAMK2_CAMK2D_ST	Q8WZ42	TTN	Q13557	CAMK2D	S15682	P15676H	15676	Missense	distal	-6	no	41.614	42.888	EPSD	ICGC;COSMIC	37.605	Up-regulation
CAMK_CAMK2_CAMK2D_ST	Q8WZ42	TTN	Q13557	CAMK2D	S15682	G15689R	15689	Missense	distal	7	no	41.614	40.844	EPSD	ICGC;COSMIC	37.605	Down-regulation
CAMK_CAMK2_CAMK2D_ST	Q8WZ42	TTN	Q13557	CAMK2D	S15682	I15683T	15683	Missense	proximal	1	no	41.614	31.414	EPSD	ICGC;COSMIC	37.605	Loss
CAMK_CAMK2_CAMK2D_ST	Q8WZ42	TTN	Q13557	CAMK2D	S15691	R15694H	15694	Missense	distal	3	no	49.674	40.127	EPSD	ICGC;COSMIC	37.605	Down-regulation
CAMK_CAMK2_CAMK2D_ST	Q8WZ42	TTN	Q13557	CAMK2D	S15691	N15685K	15685	Missense	distal	-6	no	49.674	40.708	EPSD	ICGC;COSMIC	37.605	Down-regulation
CAMK_CAMK2_CAMK2D_ST	Q8WZ42	TTN	Q13557	CAMK2D	S15691	S15698Y	15698	Missense	distal	7	no	49.674	51.964	EPSD	ICGC;COSMIC	37.605	Up-regulation
CAMK_CAMK2_CAMK2D_ST	Q8WZ42	TTN	Q13557	CAMK2D	S15691	R15694C	15694	Missense	distal	3	no	49.674	52.366	EPSD	ICGC;COSMIC	37.605	Up-regulation
CAMK_CAMK2_CAMK2D_ST	Q8WZ42	TTN	Q13557	CAMK2D	S15691	Q15692K	15692	Missense	proximal	1	no	49.674	49.558	EPSD	ICGC;COSMIC	37.605	Down-regulation
CAMK_CAMK2_CAMK2D_ST	Q8WZ42	TTN	Q13557	CAMK2D	S15691	V15695I	15695	Missense	distal	4	no	49.674	51.867	EPSD	ICGC;CCLE	37.605	Up-regulation
CAMK_CAMK2_CAMK2D_ST	Q8WZ42	TTN	Q13557	CAMK2D	S15691	G15689R	15689	Missense	proximal	-2	no	49.674	50.391	EPSD	ICGC;COSMIC	37.605	Up-regulation
CAMK_CAMK2_CAMK2D_ST	Q8WZ42	TTN	Q13557	CAMK2D	S15691	R15696L	15696	Missense	distal	5	no	49.674	48.365	EPSD	ICGC;COSMIC	37.605	Down-regulation
CAMK_CAMK2_CAMK2D_ST	Q8WZ42	TTN	Q13557	CAMK2D	S15744	S15744P	15744	Missense	central	0	yes	49.029	0.000	EPSD	ICGC;COSMIC	37.605	Loss
CAMK_CAMK2_CAMK2D_ST	Q8WZ42	TTN	Q13557	CAMK2D	S15744	K15742N	15742	Missense	proximal	-2	no	49.029	49.505	EPSD	ICGC;COSMIC	37.605	Up-regulation
CAMK_CAMK2_CAMK2D_ST	Q8WZ42	TTN	Q13557	CAMK2D	S15744	D15739Y	15739	Missense	distal	-5	no	49.029	48.148	EPSD	ICGC;COSMIC	37.605	Down-regulation
CAMK_CAMK2_CAMK2D_ST	Q8WZ42	TTN	Q13557	CAMK2D	S15744	T15743A	15743	Missense	proximal	-1	no	49.029	47.374	EPSD	ICGC;COSMIC	37.605	Down-regulation
CAMK_CAMK2_CAMK2D_ST	Q8WZ42	TTN	Q13557	CAMK2D	S15744	L15746I	15746	Missense	proximal	2	no	49.029	48.401	EPSD	ICGC;COSMIC	37.605	Down-regulation
CAMK_CAMK2_CAMK2D_ST	Q8WZ42	TTN	Q13557	CAMK2D	S15782	C15787S	15787	Missense	distal	5	no	40.880	41.364	EPSD	ICGC;COSMIC	37.605	Up-regulation
CAMK_CAMK2_CAMK2D_ST	Q8WZ42	TTN	Q13557	CAMK2D	S15782	T15783K	15783	Missense	proximal	1	no	40.880	44.231	EPSD	ICGC	37.605	Up-regulation
CAMK_CAMK2_CAMK2D_ST	Q8WZ42	TTN	Q13557	CAMK2D	S15782	V15779A	15779	Missense	distal	-3	no	40.880	27.308	EPSD	ICGC;COSMIC	37.605	Loss
CAMK_CAMK2_CAMK2D_ST	Q8WZ42	TTN	Q13557	CAMK2D	S15782	R15785I	15785	Missense	distal	3	no	40.880	32.999	EPSD	ICGC;COSMIC	37.605	Loss
CAMK_CAMK2_CAMK2D_ST	Q8WZ42	TTN	Q13557	CAMK2D	T15989	V15990I	15990	Missense	proximal	1	no	53.685	59.407	EPSD	ICGC;COSMIC	37.605	Up-regulation
CAMK_CAMK2_CAMK2D_ST	Q8WZ42	TTN	Q13557	CAMK2D	T15989	R15986L	15986	Missense	distal	-3	no	53.685	31.849	EPSD	ICGC;COSMIC	37.605	Loss
CAMK_CAMK2_CAMK2D_ST	Q8WZ42	TTN	Q13557	CAMK2D	T15989	T15989I	15989	Missense	central	0	yes	53.685	0.000	EPSD	ICGC;COSMIC	37.605	Loss
CAMK_CAMK2_CAMK2D_ST	Q8WZ42	TTN	Q13557	CAMK2D	S16236	R16233W	16233	Missense	distal	-3	no	38.509	-2.528	EPSD	ICGC	37.605	Loss
CAMK_CAMK2_CAMK2D_ST	Q8WZ42	TTN	Q13557	CAMK2D	S16236	T16229K	16229	Missense	distal	-7	no	38.509	42.957	EPSD	ICGC;COSMIC	37.605	Up-regulation
CAMK_CAMK2_CAMK2D_ST	Q8WZ42	TTN	Q13557	CAMK2D	S16236	L16240I	16240	Missense	distal	4	no	38.509	37.598	EPSD	ICGC	37.605	Loss
CAMK_CAMK2_CAMK2D_ST	Q8WZ42	TTN	Q13557	CAMK2D	S16383	E16378K	16378	Missense	distal	-5	no	46.646	45.470	EPSD	ICGC;COSMIC	37.605	Down-regulation
CAMK_CAMK2_CAMK2D_ST	Q8WZ42	TTN	Q13557	CAMK2D	S16383	R16382Q	16382	Missense	proximal	-1	no	46.646	43.742	EPSD	ICGC;COSMIC	37.605	Down-regulation
CAMK_CAMK2_CAMK2D_ST	Q8WZ42	TTN	Q13557	CAMK2D	S16383	T16387A	16387	Missense	distal	4	no	46.646	46.102	EPSD	ICGC;COSMIC	37.605	Down-regulation
CAMK_CAMK2_CAMK2D_ST	Q8WZ42	TTN	Q13557	CAMK2D	S16383	K16386N	16386	Missense	distal	3	no	46.646	48.508	EPSD	ICGC;COSMIC	37.605	Up-regulation
CAMK_CAMK2_CAMK2D_ST	Q8WZ42	TTN	Q13557	CAMK2D	S16647	T16644R	16644	Missense	distal	-3	no	20.776	42.408	EPSD	ICGC;COSMIC	37.605	Gain
CAMK_CAMK2_CAMK2D_ST	Q8WZ42	TTN	Q13557	CAMK2D	S16649	L16650I	16650	Missense	proximal	1	no	32.215	40.107	EPSD	ICGC	37.605	Gain
CAMK_CAMK2_CAMK2D_ST	Q8WZ42	TTN	Q13557	CAMK2D	S16753	G16752D	16752	Missense	proximal	-1	no	38.087	35.876	EPSD	ICGC;COSMIC	37.605	Loss
CAMK_CAMK2_CAMK2D_ST	Q8WZ42	TTN	Q13557	CAMK2D	T17118	R17114H	17114	Missense	distal	-4	no	52.106	51.173	EPSD	ICGC	37.605	Down-regulation
CAMK_CAMK2_CAMK2D_ST	Q8WZ42	TTN	Q13557	CAMK2D	T17118	R17114C	17114	Missense	distal	-4	no	52.106	49.985	EPSD	ICGC;COSMIC	37.605	Down-regulation
CAMK_CAMK2_CAMK2D_ST	Q8WZ42	TTN	Q13557	CAMK2D	T17118	A17125T	17125	Missense	distal	7	no	52.106	52.903	EPSD	ICGC;COSMIC	37.605	Up-regulation
CAMK_CAMK2_CAMK2D_ST	Q8WZ42	TTN	Q13557	CAMK2D	T17118	Y17121H	17121	Missense	distal	3	no	52.106	37.458	EPSD	ICGC;COSMIC	37.605	Loss
CAMK_CAMK2_CAMK2D_ST	Q8WZ42	TTN	Q13557	CAMK2D	T17118	R17114S	17114	Missense	distal	-4	no	52.106	49.860	EPSD	ICGC;COSMIC	37.605	Down-regulation
CAMK_CAMK2_CAMK2D_ST	Q8WZ42	TTN	Q13557	CAMK2D	T17190	R17188K	17188	Missense	proximal	-2	no	45.611	44.861	EPSD	ICGC;COSMIC	37.605	Down-regulation
CAMK_CAMK2_CAMK2D_ST	Q8WZ42	TTN	Q13557	CAMK2D	T17410	K17413M	17413	Missense	distal	3	no	44.647	40.473	EPSD	ICGC;COSMIC	37.605	Down-regulation
CAMK_CAMK2_CAMK2D_ST	Q8WZ42	TTN	Q13557	CAMK2D	T17410	L17407R	17407	Missense	distal	-3	no	44.647	66.482	EPSD	ICGC	37.605	Up-regulation
CAMK_CAMK2_CAMK2D_ST	Q8WZ42	TTN	Q13557	CAMK2D	T17591	T17594K	17594	Missense	distal	3	no	34.283	37.975	EPSD	ICGC	37.605	Gain
CAMK_CAMK2_CAMK2D_ST	Q8WZ42	TTN	Q13557	CAMK2D	T17596	W17590C	17590	Missense	distal	-6	no	33.027	38.503	EPSD	ICGC;COSMIC;CCLE	37.605	Gain
CAMK_CAMK2_CAMK2D_ST	Q8WZ42	TTN	Q13557	CAMK2D	T17603	L17607F	17607	Missense	distal	4	no	47.419	45.328	EPSD	ICGC;COSMIC	37.605	Down-regulation
CAMK_CAMK2_CAMK2D_ST	Q8WZ42	TTN	Q13557	CAMK2D	T17603	Q17605H	17605	Missense	proximal	2	no	47.419	43.710	EPSD	ICGC;COSMIC	37.605	Down-regulation
CAMK_CAMK2_CAMK2D_ST	Q8WZ42	TTN	Q13557	CAMK2D	T17603	G17606D	17606	Missense	distal	3	no	47.419	42.748	EPSD	ICGC;COSMIC	37.605	Down-regulation
CAMK_CAMK2_CAMK2D_ST	Q8WZ42	TTN	Q13557	CAMK2D	T17603	G17610E	17610	Missense	distal	7	no	47.419	48.060	EPSD	ICGC;COSMIC	37.605	Up-regulation
CAMK_CAMK2_CAMK2D_ST	Q8WZ42	TTN	Q13557	CAMK2D	S17823	T17824I	17824	Missense	proximal	1	no	50.561	60.761	EPSD	ICGC;COSMIC	37.605	Up-regulation
CAMK_CAMK2_CAMK2D_ST	Q8WZ42	TTN	Q13557	CAMK2D	S17823	E17821D	17821	Missense	proximal	-2	no	50.561	50.567	EPSD	ICGC;COSMIC	37.605	Up-regulation
CAMK_CAMK2_CAMK2D_ST	Q8WZ42	TTN	Q13557	CAMK2D	S17823	T17824K	17824	Missense	proximal	1	no	50.561	53.912	EPSD	ICGC;COSMIC	37.605	Up-regulation
CAMK_CAMK2_CAMK2D_ST	Q8WZ42	TTN	Q13557	CAMK2D	S17823	V17820M	17820	Missense	distal	-3	no	50.561	52.580	EPSD	ICGC;COSMIC	37.605	Up-regulation
CAMK_CAMK2_CAMK2D_ST	Q8WZ42	TTN	Q13557	CAMK2D	S17823	V17818M	17818	Missense	distal	-5	no	50.561	49.861	EPSD	ICGC;COSMIC	37.605	Down-regulation
CAMK_CAMK2_CAMK2D_ST	Q8WZ42	TTN	Q13557	CAMK2D	S17823	R17827T	17827	Missense	distal	4	no	50.561	49.522	EPSD	ICGC;COSMIC	37.605	Down-regulation
CAMK_CAMK2_CAMK2D_ST	Q8WZ42	TTN	Q13557	CAMK2D	S17823	V17820L	17820	Missense	distal	-3	no	50.561	41.109	EPSD	ICGC;COSMIC	37.605	Down-regulation
CAMK_CAMK2_CAMK2D_ST	Q8WZ42	TTN	Q13557	CAMK2D	S17929	R17935C	17935	Missense	distal	6	no	42.182	41.505	EPSD	ICGC;COSMIC	37.605	Down-regulation
CAMK_CAMK2_CAMK2D_ST	Q8WZ42	TTN	Q13557	CAMK2D	S17929	L17925M	17925	Missense	distal	-4	no	42.182	42.102	EPSD	ICGC;COSMIC	37.605	Down-regulation
CAMK_CAMK2_CAMK2D_ST	Q8WZ42	TTN	Q13557	CAMK2D	S17929	F17936I	17936	Missense	distal	7	no	42.182	43.035	EPSD	ICGC;COSMIC	37.605	Up-regulation
CAMK_CAMK2_CAMK2D_ST	Q8WZ42	TTN	Q13557	CAMK2D	S17929	M17930I	17930	Missense	proximal	1	no	42.182	43.030	EPSD	ICGC;COSMIC	37.605	Up-regulation
CAMK_CAMK2_CAMK2D_ST	Q8WZ42	TTN	Q13557	CAMK2D	S17929	V17926M	17926	Missense	distal	-3	no	42.182	44.201	EPSD	ICGC;COSMIC	37.605	Up-regulation
CAMK_CAMK2_CAMK2D_ST	Q8WZ42	TTN	Q13557	CAMK2D	S17929	S17929L	17929	Missense	central	0	yes	42.182	0.000	EPSD	ICGC;COSMIC	37.605	Loss
CAMK_CAMK2_CAMK2D_ST	Q8WZ42	TTN	Q13557	CAMK2D	S17929	S17929P	17929	Missense	central	0	yes	42.182	0.000	EPSD	ICGC	37.605	Loss
CAMK_CAMK2_CAMK2D_ST	Q8WZ42	TTN	Q13557	CAMK2D	T17979	R17983L	17983	Missense	distal	4	no	44.039	44.919	EPSD	ICGC;COSMIC	37.605	Up-regulation
CAMK_CAMK2_CAMK2D_ST	Q8WZ42	TTN	Q13557	CAMK2D	T17979	I17973M	17973	Missense	distal	-6	no	44.039	45.190	EPSD	ICGC;COSMIC	37.605	Up-regulation
CAMK_CAMK2_CAMK2D_ST	Q8WZ42	TTN	Q13557	CAMK2D	T17979	L17974M	17974	Missense	distal	-5	no	44.039	44.821	EPSD	ICGC;COSMIC	37.605	Up-regulation
CAMK_CAMK2_CAMK2D_ST	Q8WZ42	TTN	Q13557	CAMK2D	T17979	K17976N	17976	Missense	distal	-3	no	44.039	35.748	EPSD	ICGC;COSMIC	37.605	Loss
CAMK_CAMK2_CAMK2D_ST	Q8WZ42	TTN	Q13557	CAMK2D	T17979	S17981F	17981	Missense	proximal	2	no	44.039	37.843	EPSD	ICGC	37.605	Down-regulation
CAMK_CAMK2_CAMK2D_ST	Q8WZ42	TTN	Q13557	CAMK2D	T17979	S17981P	17981	Missense	proximal	2	no	44.039	41.618	EPSD	ICGC;COSMIC	37.605	Down-regulation
CAMK_CAMK2_CAMK2D_ST	Q8WZ42	TTN	Q13557	CAMK2D	T17988	R17983L	17983	Missense	distal	-5	no	51.440	51.652	EPSD	ICGC;COSMIC	37.605	Up-regulation
CAMK_CAMK2_CAMK2D_ST	Q8WZ42	TTN	Q13557	CAMK2D	T17988	Y17995C	17995	Missense	distal	7	no	51.440	51.127	EPSD	ICGC;COSMIC	37.605	Down-regulation
CAMK_CAMK2_CAMK2D_ST	Q8WZ42	TTN	Q13557	CAMK2D	T17988	H17993N	17993	Missense	distal	5	no	51.440	50.716	EPSD	ICGC	37.605	Down-regulation
CAMK_CAMK2_CAMK2D_ST	Q8WZ42	TTN	Q13557	CAMK2D	T17988	P17994A	17994	Missense	distal	6	no	51.440	48.501	EPSD	ICGC;COSMIC	37.605	Down-regulation
CAMK_CAMK2_CAMK2D_ST	Q8WZ42	TTN	Q13557	CAMK2D	T17988	V17987G	17987	Missense	proximal	-1	no	51.440	50.876	EPSD	ICGC;COSMIC	37.605	Down-regulation
CAMK_CAMK2_CAMK2D_ST	Q8WZ42	TTN	Q13557	CAMK2D	T17988	S17981F	17981	Missense	distal	-7	no	51.440	48.776	EPSD	ICGC	37.605	Down-regulation
CAMK_CAMK2_CAMK2D_ST	Q8WZ42	TTN	Q13557	CAMK2D	T17988	S17981P	17981	Missense	distal	-7	no	51.440	48.189	EPSD	ICGC;COSMIC	37.605	Down-regulation
CAMK_CAMK2_CAMK2D_ST	Q8WZ42	TTN	Q13557	CAMK2D	T18104	T18104A	18104	Missense	central	0	yes	41.420	0.000	EPSD	ICGC;COSMIC	37.605	Loss
CAMK_CAMK2_CAMK2D_ST	Q8WZ42	TTN	Q13557	CAMK2D	T18104	R18107W	18107	Missense	distal	3	no	41.420	29.320	EPSD	ICGC;COSMIC	37.605	Loss
CAMK_CAMK2_CAMK2D_ST	Q8WZ42	TTN	Q13557	CAMK2D	T18104	K18102N	18102	Missense	proximal	-2	no	41.420	41.895	EPSD	ICGC;COSMIC	37.605	Up-regulation
CAMK_CAMK2_CAMK2D_ST	Q8WZ42	TTN	Q13557	CAMK2D	T18104	K18102T	18102	Missense	proximal	-2	no	41.420	40.812	EPSD	ICGC;COSMIC	37.605	Down-regulation
CAMK_CAMK2_CAMK2D_ST	Q8WZ42	TTN	Q13557	CAMK2D	T18104	G18105D	18105	Missense	proximal	1	no	41.420	36.495	EPSD	ICGC	37.605	Loss
CAMK_CAMK2_CAMK2D_ST	Q8WZ42	TTN	Q13557	CAMK2D	T18104	T18104N	18104	Missense	central	0	yes	41.420	0.000	EPSD	ICGC;COSMIC	37.605	Loss
CAMK_CAMK2_CAMK2D_ST	Q8WZ42	TTN	Q13557	CAMK2D	T18388	D18382N	18382	Missense	distal	-6	no	30.112	43.274	EPSD	ICGC;COSMIC	37.605	Gain
CAMK_CAMK2_CAMK2D_ST	Q8WZ42	TTN	Q13557	CAMK2D	T18505	N18499S	18499	Missense	distal	-6	no	50.752	41.099	EPSD	ICGC;COSMIC	37.605	Down-regulation
CAMK_CAMK2_CAMK2D_ST	Q8WZ42	TTN	Q13557	CAMK2D	T18505	K18498T	18498	Missense	distal	-7	no	50.752	46.304	EPSD	ICGC	37.605	Down-regulation
CAMK_CAMK2_CAMK2D_ST	Q8WZ42	TTN	Q13557	CAMK2D	T18505	E18507K	18507	Missense	proximal	2	no	50.752	46.435	EPSD	ICGC;COSMIC	37.605	Down-regulation
CAMK_CAMK2_CAMK2D_ST	Q8WZ42	TTN	Q13557	CAMK2D	T18577	V18580G	18580	Missense	distal	3	no	52.395	62.297	EPSD	ICGC;COSMIC	37.605	Up-regulation
CAMK_CAMK2_CAMK2D_ST	Q8WZ42	TTN	Q13557	CAMK2D	T18577	D18576E	18576	Missense	proximal	-1	no	52.395	54.752	EPSD	ICGC;COSMIC	37.605	Up-regulation
CAMK_CAMK2_CAMK2D_ST	Q8WZ42	TTN	Q13557	CAMK2D	S18583	V18580G	18580	Missense	distal	-3	no	51.346	20.772	EPSD	ICGC;COSMIC	37.605	Loss
CAMK_CAMK2_CAMK2D_ST	Q8WZ42	TTN	Q13557	CAMK2D	S18583	D18576E	18576	Missense	distal	-7	no	51.346	51.664	EPSD	ICGC;COSMIC	37.605	Up-regulation
CAMK_CAMK2_CAMK2D_ST	Q8WZ42	TTN	Q13557	CAMK2D	S18583	S18586I	18586	Missense	distal	3	no	51.346	41.809	EPSD	ICGC;COSMIC	37.605	Down-regulation
CAMK_CAMK2_CAMK2D_ST	Q8WZ42	TTN	Q13557	CAMK2D	T18682	A18685T	18685	Missense	distal	3	no	54.214	41.087	EPSD	ICGC;COSMIC	37.605	Down-regulation
CAMK_CAMK2_CAMK2D_ST	Q8WZ42	TTN	Q13557	CAMK2D	T18682	K18688N	18688	Missense	distal	6	no	54.214	55.112	EPSD	ICGC	37.605	Up-regulation
CAMK_CAMK2_CAMK2D_ST	Q8WZ42	TTN	Q13557	CAMK2D	T18682	N18680K	18680	Missense	proximal	-2	no	54.214	53.739	EPSD	ICGC	37.605	Down-regulation
CAMK_CAMK2_CAMK2D_ST	Q8WZ42	TTN	Q13557	CAMK2D	T18682	K18681Q	18681	Missense	proximal	-1	no	54.214	52.726	EPSD	ICGC;COSMIC	37.605	Down-regulation
CAMK_CAMK2_CAMK2D_ST	Q8WZ42	TTN	Q13557	CAMK2D	S18823	E18816K	18816	Missense	distal	-7	no	36.065	42.333	EPSD	ICGC;COSMIC	37.605	Gain
CAMK_CAMK2_CAMK2D_ST	Q8WZ42	TTN	Q13557	CAMK2D	S18823	E18819K	18819	Missense	distal	-4	no	36.065	39.320	EPSD	ICGC;COSMIC	37.605	Gain
CAMK_CAMK2_CAMK2D_ST	Q8WZ42	TTN	Q13557	CAMK2D	T18852	V18847M	18847	Missense	distal	-5	no	43.296	42.597	EPSD	ICGC;COSMIC	37.605	Down-regulation
CAMK_CAMK2_CAMK2D_ST	Q8WZ42	TTN	Q13557	CAMK2D	T18852	T18846N	18846	Missense	distal	-6	no	43.296	55.921	EPSD	ICGC;COSMIC	37.605	Up-regulation
CAMK_CAMK2_CAMK2D_ST	Q8WZ42	TTN	Q13557	CAMK2D	T18852	R18854S	18854	Missense	proximal	2	no	43.296	44.103	EPSD	ICGC;COSMIC	37.605	Up-regulation
CAMK_CAMK2_CAMK2D_ST	Q8WZ42	TTN	Q13557	CAMK2D	T18852	R18858Q	18858	Missense	distal	6	no	43.296	45.847	EPSD	ICGC;COSMIC;CCLE	37.605	Up-regulation
CAMK_CAMK2_CAMK2D_ST	Q8WZ42	TTN	Q13557	CAMK2D	T18852	R18854H	18854	Missense	proximal	2	no	43.296	40.340	EPSD	ICGC;COSMIC	37.605	Down-regulation
CAMK_CAMK2_CAMK2D_ST	Q8WZ42	TTN	Q13557	CAMK2D	S18976	Q18972L	18972	Missense	distal	-4	no	55.000	54.747	EPSD	ICGC;COSMIC	37.605	Down-regulation
CAMK_CAMK2_CAMK2D_ST	Q8WZ42	TTN	Q13557	CAMK2D	S18976	V18978F	18978	Missense	proximal	2	no	55.000	53.298	EPSD	ICGC;COSMIC	37.605	Down-regulation
CAMK_CAMK2_CAMK2D_ST	Q8WZ42	TTN	Q13557	CAMK2D	T19012	T19017I	19017	Missense	distal	5	no	39.808	39.414	EPSD	ICGC;COSMIC	37.605	Down-regulation
CAMK_CAMK2_CAMK2D_ST	Q8WZ42	TTN	Q13557	CAMK2D	T19012	T19015I	19015	Missense	distal	3	no	39.808	36.935	EPSD	ICGC;COSMIC	37.605	Loss
CAMK_CAMK2_CAMK2D_ST	Q8WZ42	TTN	Q13557	CAMK2D	T19012	E19014K	19014	Missense	proximal	2	no	39.808	35.491	EPSD	ICGC;COSMIC;CCLE	37.605	Loss
CAMK_CAMK2_CAMK2D_ST	Q8WZ42	TTN	Q13557	CAMK2D	S19081	H19078R	19078	Missense	distal	-3	no	21.884	59.208	EPSD	ICGC;COSMIC	37.605	Gain
CAMK_CAMK2_CAMK2D_ST	Q8WZ42	TTN	Q13557	CAMK2D	T19272	K19266Q	19266	Missense	distal	-6	no	32.861	38.134	EPSD	ICGC;COSMIC	37.605	Gain
CAMK_CAMK2_CAMK2D_ST	Q8WZ42	TTN	Q13557	CAMK2D	S19375	W19369C	19369	Missense	distal	-6	no	33.037	38.513	EPSD	ICGC;COSMIC	37.605	Gain
CAMK_CAMK2_CAMK2D_ST	Q8WZ42	TTN	Q13557	CAMK2D	S19893	D19892N	19892	Missense	proximal	-1	no	45.314	47.300	EPSD	ICGC	37.605	Up-regulation
CAMK_CAMK2_CAMK2D_ST	Q8WZ42	TTN	Q13557	CAMK2D	S19893	D19892Y	19892	Missense	proximal	-1	no	45.314	46.829	EPSD	ICGC	37.605	Up-regulation
CAMK_CAMK2_CAMK2D_ST	Q8WZ42	TTN	Q13557	CAMK2D	S20101	Y20094C	20094	Missense	distal	-7	no	35.620	38.532	EPSD	ICGC;COSMIC	37.605	Gain
CAMK_CAMK2_CAMK2D_ST	Q8WZ42	TTN	Q13557	CAMK2D	T20168	C20166W	20166	Missense	proximal	-2	no	50.073	49.932	EPSD	ICGC;COSMIC	37.605	Down-regulation
CAMK_CAMK2_CAMK2D_ST	Q8WZ42	TTN	Q13557	CAMK2D	T20168	R20165W	20165	Missense	distal	-3	no	50.073	9.036	EPSD	ICGC;COSMIC	37.605	Loss
CAMK_CAMK2_CAMK2D_ST	Q8WZ42	TTN	Q13557	CAMK2D	T20168	H20171Q	20171	Missense	distal	3	no	50.073	58.724	EPSD	ICGC	37.605	Up-regulation
CAMK_CAMK2_CAMK2D_ST	Q8WZ42	TTN	Q13557	CAMK2D	T20168	P20174S	20174	Missense	distal	6	no	50.073	44.171	EPSD	ICGC	37.605	Down-regulation
CAMK_CAMK2_CAMK2D_ST	Q8WZ42	TTN	Q13557	CAMK2D	T20181	P20174S	20174	Missense	distal	-7	no	35.349	38.600	EPSD	ICGC	37.605	Gain
CAMK_CAMK2_CAMK2D_ST	Q8WZ42	TTN	Q13557	CAMK2D	S20202	P20203Q	20203	Missense	proximal	1	no	37.251	41.949	EPSD	ICGC;COSMIC	37.605	Gain
CAMK_CAMK2_CAMK2D_ST	Q8WZ42	TTN	Q13557	CAMK2D	S20205	P20207H	20207	Missense	proximal	2	no	37.917	36.575	EPSD	ICGC	37.605	Loss
CAMK_CAMK2_CAMK2D_ST	Q8WZ42	TTN	Q13557	CAMK2D	S20205	P20204H	20204	Missense	proximal	-1	no	37.917	37.800	EPSD	ICGC;COSMIC	37.605	Down-regulation
CAMK_CAMK2_CAMK2D_ST	Q8WZ42	TTN	Q13557	CAMK2D	S20205	P20204T	20204	Missense	proximal	-1	no	37.917	41.284	EPSD	ICGC;COSMIC	37.605	Up-regulation
CAMK_CAMK2_CAMK2D_ST	Q8WZ42	TTN	Q13557	CAMK2D	S20205	P20203Q	20203	Missense	proximal	-2	no	37.917	37.834	EPSD	ICGC;COSMIC	37.605	Down-regulation
CAMK_CAMK2_CAMK2D_ST	Q8WZ42	TTN	Q13557	CAMK2D	S20205	D20209G	20209	Missense	distal	4	no	37.917	39.236	EPSD	ICGC	37.605	Up-regulation
CAMK_CAMK2_CAMK2D_ST	Q8WZ42	TTN	Q13557	CAMK2D	S20300	T20294N	20294	Missense	distal	-6	no	27.114	39.739	EPSD	ICGC;COSMIC	37.605	Gain
CAMK_CAMK2_CAMK2D_ST	Q8WZ42	TTN	Q13557	CAMK2D	T20307	S20303C	20303	Missense	distal	-4	no	43.366	43.490	EPSD	ICGC;COSMIC	37.605	Up-regulation
CAMK_CAMK2_CAMK2D_ST	Q8WZ42	TTN	Q13557	CAMK2D	T20307	L20310F	20310	Missense	distal	3	no	43.366	47.433	EPSD	ICGC;COSMIC	37.605	Up-regulation
CAMK_CAMK2_CAMK2D_ST	Q8WZ42	TTN	Q13557	CAMK2D	T20477	A20476T	20476	Missense	proximal	-1	no	49.398	51.053	EPSD	ICGC	37.605	Up-regulation
CAMK_CAMK2_CAMK2D_ST	Q8WZ42	TTN	Q13557	CAMK2D	T20477	R20472T	20472	Missense	distal	-5	no	49.398	50.839	EPSD	ICGC;COSMIC	37.605	Up-regulation
CAMK_CAMK2_CAMK2D_ST	Q8WZ42	TTN	Q13557	CAMK2D	T20477	E20484K	20484	Missense	distal	7	no	49.398	49.477	EPSD	ICGC;COSMIC	37.605	Up-regulation
CAMK_CAMK2_CAMK2D_ST	Q8WZ42	TTN	Q13557	CAMK2D	T20477	G20482S	20482	Missense	distal	5	no	49.398	48.448	EPSD	ICGC;COSMIC	37.605	Down-regulation
CAMK_CAMK2_CAMK2D_ST	Q8WZ42	TTN	Q13557	CAMK2D	T20721	V20718I	20718	Missense	distal	-3	no	51.310	50.590	EPSD	ICGC;COSMIC	37.605	Down-regulation
CAMK_CAMK2_CAMK2D_ST	Q8WZ42	TTN	Q13557	CAMK2D	T20721	S20726P	20726	Missense	distal	5	no	51.310	54.162	EPSD	ICGC	37.605	Up-regulation
CAMK_CAMK2_CAMK2D_ST	Q8WZ42	TTN	Q13557	CAMK2D	T20721	T20721N	20721	Missense	central	0	yes	51.310	0.000	EPSD	ICGC	37.605	Loss
CAMK_CAMK2_CAMK2D_ST	Q8WZ42	TTN	Q13557	CAMK2D	T20721	E20724K	20724	Missense	distal	3	no	51.310	45.290	EPSD	ICGC;COSMIC	37.605	Down-regulation
CAMK_CAMK2_CAMK2D_ST	Q8WZ42	TTN	Q13557	CAMK2D	T20765	T20762K	20762	Missense	distal	-3	no	33.064	43.287	EPSD	ICGC;COSMIC	37.605	Gain
CAMK_CAMK2_CAMK2D_ST	Q8WZ42	TTN	Q13557	CAMK2D	S20864	Q20857K	20857	Missense	distal	-7	no	43.845	48.681	EPSD	ICGC	37.605	Up-regulation
CAMK_CAMK2_CAMK2D_ST	Q8WZ42	TTN	Q13557	CAMK2D	S20864	D20871Y	20871	Missense	distal	7	no	43.845	44.217	EPSD	ICGC;COSMIC	37.605	Up-regulation
CAMK_CAMK2_CAMK2D_ST	Q8WZ42	TTN	Q13557	CAMK2D	S20864	S20864G	20864	Missense	central	0	yes	43.845	0.000	EPSD	ICGC;COSMIC	37.605	Loss
CAMK_CAMK2_CAMK2D_ST	Q8WZ42	TTN	Q13557	CAMK2D	S20864	S20868P	20868	Missense	distal	4	no	43.845	44.073	EPSD	ICGC;COSMIC	37.605	Up-regulation
CAMK_CAMK2_CAMK2D_ST	Q8WZ42	TTN	Q13557	CAMK2D	S20864	D20871N	20871	Missense	distal	7	no	43.845	43.114	EPSD	ICGC	37.605	Down-regulation
CAMK_CAMK2_CAMK2D_ST	Q8WZ42	TTN	Q13557	CAMK2D	S20864	R20858Q	20858	Missense	distal	-6	no	43.845	46.707	EPSD	ICGC;COSMIC	37.605	Up-regulation
CAMK_CAMK2_CAMK2D_ST	Q8WZ42	TTN	Q13557	CAMK2D	S20864	K20870R	20870	Missense	distal	6	no	43.845	44.498	EPSD	ICGC;COSMIC	37.605	Up-regulation
CAMK_CAMK2_CAMK2D_ST	Q8WZ42	TTN	Q13557	CAMK2D	T20873	K20870R	20870	Missense	distal	-3	no	28.034	39.442	EPSD	ICGC;COSMIC	37.605	Gain
CAMK_CAMK2_CAMK2D_ST	Q8WZ42	TTN	Q13557	CAMK2D	T20994	K20998M	20998	Missense	distal	4	no	47.634	46.846	EPSD	ICGC;COSMIC	37.605	Down-regulation
CAMK_CAMK2_CAMK2D_ST	Q8WZ42	TTN	Q13557	CAMK2D	T20994	G20993R	20993	Missense	proximal	-1	no	47.634	49.590	EPSD	ICGC;COSMIC	37.605	Up-regulation
CAMK_CAMK2_CAMK2D_ST	Q8WZ42	TTN	Q13557	CAMK2D	T20994	G21001C	21001	Missense	distal	7	no	47.634	48.684	EPSD	ICGC;COSMIC	37.605	Up-regulation
CAMK_CAMK2_CAMK2D_ST	Q8WZ42	TTN	Q13557	CAMK2D	T20994	K20991N	20991	Missense	distal	-3	no	47.634	39.342	EPSD	ICGC	37.605	Down-regulation
CAMK_CAMK2_CAMK2D_ST	Q8WZ42	TTN	Q13557	CAMK2D	S21055	N21048K	21048	Missense	distal	-7	no	37.318	44.104	EPSD	ICGC	37.605	Gain
CAMK_CAMK2_CAMK2D_ST	Q8WZ42	TTN	Q13557	CAMK2D	S21055	T21052M	21052	Missense	distal	-3	no	37.318	48.584	EPSD	ICGC;COSMIC	37.605	Gain
CAMK_CAMK2_CAMK2D_ST	Q8WZ42	TTN	Q13557	CAMK2D	S21055	Q21058R	21058	Missense	distal	3	no	37.318	38.214	EPSD	ICGC;COSMIC	37.605	Gain
CAMK_CAMK2_CAMK2D_ST	Q8WZ42	TTN	Q13557	CAMK2D	S21078	A21079V	21079	Missense	proximal	1	no	33.608	40.040	EPSD	ICGC;COSMIC	37.605	Gain
CAMK_CAMK2_CAMK2D_ST	Q8WZ42	TTN	Q13557	CAMK2D	S21338	P21334T	21334	Missense	distal	-4	no	49.062	50.527	EPSD	ICGC;COSMIC	37.605	Up-regulation
CAMK_CAMK2_CAMK2D_ST	Q8WZ42	TTN	Q13557	CAMK2D	S21338	A21343V	21343	Missense	distal	5	no	49.062	48.850	EPSD	ICGC;COSMIC	37.605	Down-regulation
CAMK_CAMK2_CAMK2D_ST	Q8WZ42	TTN	Q13557	CAMK2D	S21338	P21336Q	21336	Missense	proximal	-2	no	49.062	48.978	EPSD	ICGC	37.605	Down-regulation
CAMK_CAMK2_CAMK2D_ST	Q8WZ42	TTN	Q13557	CAMK2D	S21338	L21331I	21331	Missense	distal	-7	no	49.062	48.488	EPSD	ICGC;COSMIC	37.605	Down-regulation
CAMK_CAMK2_CAMK2D_ST	Q8WZ42	TTN	Q13557	CAMK2D	S21338	G21344E	21344	Missense	distal	6	no	49.062	47.389	EPSD	ICGC;COSMIC	37.605	Down-regulation
CAMK_CAMK2_CAMK2D_ST	Q8WZ42	TTN	Q13557	CAMK2D	S21338	L21331V	21331	Missense	distal	-7	no	49.062	43.070	EPSD	ICGC	37.605	Down-regulation
CAMK_CAMK2_CAMK2D_ST	Q8WZ42	TTN	Q13557	CAMK2D	S21554	T21551K	21551	Missense	distal	-3	no	29.680	39.903	EPSD	ICGC	37.605	Gain
CAMK_CAMK2_CAMK2D_ST	Q8WZ42	TTN	Q13557	CAMK2D	T21651	A21654S	21654	Missense	distal	3	no	37.852	31.389	EPSD	ICGC;COSMIC	37.605	Loss
CAMK_CAMK2_CAMK2D_ST	Q8WZ42	TTN	Q13557	CAMK2D	T21651	L21655I	21655	Missense	distal	4	no	37.852	36.941	EPSD	ICGC;COSMIC;CCLE	37.605	Loss
CAMK_CAMK2_CAMK2D_ST	Q8WZ42	TTN	Q13557	CAMK2D	T21651	K21648Q	21648	Missense	distal	-3	no	37.852	38.037	EPSD	ICGC	37.605	Up-regulation
CAMK_CAMK2_CAMK2D_ST	Q8WZ42	TTN	Q13557	CAMK2D	T21651	A21654T	21654	Missense	distal	3	no	37.852	24.724	EPSD	ICGC;COSMIC	37.605	Loss
CAMK_CAMK2_CAMK2D_ST	Q8WZ42	TTN	Q13557	CAMK2D	T21651	E21644K	21644	Missense	distal	-7	no	37.852	44.119	EPSD	ICGC;COSMIC	37.605	Up-regulation
CAMK_CAMK2_CAMK2D_ST	Q8WZ42	TTN	Q13557	CAMK2D	T21651	T21650I	21650	Missense	proximal	-1	no	37.852	36.891	EPSD	ICGC;COSMIC	37.605	Loss
CAMK_CAMK2_CAMK2D_ST	Q8WZ42	TTN	Q13557	CAMK2D	S21755	S21755L	21755	Missense	central	0	yes	38.251	0.000	EPSD	ICGC;COSMIC	37.605	Loss
CAMK_CAMK2_CAMK2D_ST	Q8WZ42	TTN	Q13557	CAMK2D	S21755	A21748V	21748	Missense	distal	-7	no	38.251	36.286	EPSD	ICGC;COSMIC	37.605	Loss
CAMK_CAMK2_CAMK2D_ST	Q8WZ42	TTN	Q13557	CAMK2D	S21755	L21758R	21758	Missense	distal	3	no	38.251	46.486	EPSD	ICGC;COSMIC	37.605	Up-regulation
CAMK_CAMK2_CAMK2D_ST	Q8WZ42	TTN	Q13557	CAMK2D	S21755	A21748D	21748	Missense	distal	-7	no	38.251	36.002	EPSD	ICGC	37.605	Loss
CAMK_CAMK2_CAMK2D_ST	Q8WZ42	TTN	Q13557	CAMK2D	S21755	E21754G	21754	Missense	proximal	-1	no	38.251	38.105	EPSD	ICGC	37.605	Down-regulation
CAMK_CAMK2_CAMK2D_ST	Q8WZ42	TTN	Q13557	CAMK2D	S21755	N21749D	21749	Missense	distal	-6	no	38.251	25.089	EPSD	ICGC;COSMIC	37.605	Loss
CAMK_CAMK2_CAMK2D_ST	Q8WZ42	TTN	Q13557	CAMK2D	S21755	F21756L	21756	Missense	proximal	1	no	38.251	29.696	EPSD	ICGC;COSMIC	37.605	Loss
CAMK_CAMK2_CAMK2D_ST	Q8WZ42	TTN	Q13557	CAMK2D	S21755	T21753M	21753	Missense	proximal	-2	no	38.251	39.378	EPSD	ICGC;COSMIC	37.605	Up-regulation
CAMK_CAMK2_CAMK2D_ST	Q8WZ42	TTN	Q13557	CAMK2D	T21794	R21790T	21790	Missense	distal	-4	no	46.526	46.305	EPSD	ICGC;COSMIC	37.605	Down-regulation
CAMK_CAMK2_CAMK2D_ST	Q8WZ42	TTN	Q13557	CAMK2D	T21794	T21794M	21794	Missense	central	0	yes	46.526	0.000	EPSD	ICGC;COSMIC	37.605	Loss
CAMK_CAMK2_CAMK2D_ST	Q8WZ42	TTN	Q13557	CAMK2D	T21794	G21796S	21796	Missense	proximal	2	no	46.526	44.445	EPSD	ICGC;COSMIC	37.605	Down-regulation
CAMK_CAMK2_CAMK2D_ST	Q8WZ42	TTN	Q13557	CAMK2D	T21794	L21799I	21799	Missense	distal	5	no	46.526	48.127	EPSD	ICGC	37.605	Up-regulation
CAMK_CAMK2_CAMK2D_ST	Q8WZ42	TTN	Q13557	CAMK2D	T21837	R21834H	21834	Missense	distal	-3	no	43.273	5.948	EPSD	ICGC;COSMIC	37.605	Loss
CAMK_CAMK2_CAMK2D_ST	Q8WZ42	TTN	Q13557	CAMK2D	T21837	S21842F	21842	Missense	distal	5	no	43.273	41.413	EPSD	ICGC;COSMIC	37.605	Down-regulation
CAMK_CAMK2_CAMK2D_ST	Q8WZ42	TTN	Q13557	CAMK2D	T21837	S21842Y	21842	Missense	distal	5	no	43.273	43.515	EPSD	ICGC	37.605	Up-regulation
CAMK_CAMK2_CAMK2D_ST	Q8WZ42	TTN	Q13557	CAMK2D	T21837	E21835G	21835	Missense	proximal	-2	no	43.273	43.543	EPSD	ICGC	37.605	Up-regulation
CAMK_CAMK2_CAMK2D_ST	Q8WZ42	TTN	Q13557	CAMK2D	T21837	K21839T	21839	Missense	proximal	2	no	43.273	43.933	EPSD	ICGC	37.605	Up-regulation
CAMK_CAMK2_CAMK2D_ST	Q8WZ42	TTN	Q13557	CAMK2D	T21837	R21838Q	21838	Missense	proximal	1	no	43.273	38.111	EPSD	ICGC;COSMIC	37.605	Down-regulation
CAMK_CAMK2_CAMK2D_ST	Q8WZ42	TTN	Q13557	CAMK2D	T21837	S21840Y	21840	Missense	distal	3	no	43.273	46.718	EPSD	ICGC;COSMIC	37.605	Up-regulation
CAMK_CAMK2_CAMK2D_ST	Q8WZ42	TTN	Q13557	CAMK2D	T21837	E21832K	21832	Missense	distal	-5	no	43.273	42.097	EPSD	ICGC;COSMIC	37.605	Down-regulation
CAMK_CAMK2_CAMK2D_ST	Q8WZ42	TTN	Q13557	CAMK2D	T21837	R21838W	21838	Missense	proximal	1	no	43.273	37.756	EPSD	ICGC;COSMIC	37.605	Down-regulation
CAMK_CAMK2_CAMK2D_ST	Q8WZ42	TTN	Q13557	CAMK2D	S21840	R21834H	21834	Missense	distal	-6	no	42.901	40.725	EPSD	ICGC;COSMIC	37.605	Down-regulation
CAMK_CAMK2_CAMK2D_ST	Q8WZ42	TTN	Q13557	CAMK2D	S21840	S21842F	21842	Missense	proximal	2	no	42.901	36.705	EPSD	ICGC;COSMIC	37.605	Loss
CAMK_CAMK2_CAMK2D_ST	Q8WZ42	TTN	Q13557	CAMK2D	S21840	S21842Y	21842	Missense	proximal	2	no	42.901	35.860	EPSD	ICGC	37.605	Loss
CAMK_CAMK2_CAMK2D_ST	Q8WZ42	TTN	Q13557	CAMK2D	S21840	E21835G	21835	Missense	distal	-5	no	42.901	43.487	EPSD	ICGC	37.605	Up-regulation
CAMK_CAMK2_CAMK2D_ST	Q8WZ42	TTN	Q13557	CAMK2D	S21840	K21839T	21839	Missense	proximal	-1	no	42.901	43.322	EPSD	ICGC	37.605	Up-regulation
CAMK_CAMK2_CAMK2D_ST	Q8WZ42	TTN	Q13557	CAMK2D	S21840	R21838Q	21838	Missense	proximal	-2	no	42.901	42.382	EPSD	ICGC;COSMIC	37.605	Down-regulation
CAMK_CAMK2_CAMK2D_ST	Q8WZ42	TTN	Q13557	CAMK2D	S21840	S21840Y	21840	Missense	central	0	yes	42.901	0.000	EPSD	ICGC;COSMIC	37.605	Loss
CAMK_CAMK2_CAMK2D_ST	Q8WZ42	TTN	Q13557	CAMK2D	S21840	R21838W	21838	Missense	proximal	-2	no	42.901	41.715	EPSD	ICGC;COSMIC	37.605	Down-regulation
CAMK_CAMK2_CAMK2D_ST	Q8WZ42	TTN	Q13557	CAMK2D	T21846	S21842Y	21842	Missense	distal	-4	no	35.790	38.344	EPSD	ICGC	37.605	Gain
CAMK_CAMK2_CAMK2D_ST	Q8WZ42	TTN	Q13557	CAMK2D	S21935	I21928N	21928	Missense	distal	-7	no	38.017	32.112	EPSD	ICGC;COSMIC	37.605	Loss
CAMK_CAMK2_CAMK2D_ST	Q8WZ42	TTN	Q13557	CAMK2D	S21935	G21934S	21934	Missense	proximal	-1	no	38.017	38.820	EPSD	ICGC;COSMIC	37.605	Up-regulation
CAMK_CAMK2_CAMK2D_ST	Q8WZ42	TTN	Q13557	CAMK2D	S21935	T21942P	21942	Missense	distal	7	no	38.017	36.888	EPSD	ICGC;COSMIC	37.605	Loss
CAMK_CAMK2_CAMK2D_ST	Q8WZ42	TTN	Q13557	CAMK2D	T22152	L22154S	22154	Missense	proximal	2	no	55.095	53.647	EPSD	ICGC;COSMIC	37.605	Down-regulation
CAMK_CAMK2_CAMK2D_ST	Q8WZ42	TTN	Q13557	CAMK2D	T22152	R22159H	22159	Missense	distal	7	no	55.095	56.168	EPSD	ICGC;COSMIC	37.605	Up-regulation
CAMK_CAMK2_CAMK2D_ST	Q8WZ42	TTN	Q13557	CAMK2D	T22152	R22149H	22149	Missense	distal	-3	no	55.095	17.771	EPSD	ICGC;COSMIC	37.605	Loss
CAMK_CAMK2_CAMK2D_ST	Q8WZ42	TTN	Q13557	CAMK2D	T22152	G22153E	22153	Missense	proximal	1	no	55.095	54.098	EPSD	ICGC;COSMIC	37.605	Down-regulation
CAMK_CAMK2_CAMK2D_ST	Q8WZ42	TTN	Q13557	CAMK2D	T22152	R22159C	22159	Missense	distal	7	no	55.095	56.915	EPSD	ICGC;COSMIC	37.605	Up-regulation
CAMK_CAMK2_CAMK2D_ST	Q8WZ42	TTN	Q13557	CAMK2D	T22152	T22148I	22148	Missense	distal	-4	no	55.095	53.741	EPSD	ICGC	37.605	Down-regulation
CAMK_CAMK2_CAMK2D_ST	Q8WZ42	TTN	Q13557	CAMK2D	S22456	A22463V	22463	Missense	distal	7	no	50.123	50.068	EPSD	ICGC	37.605	Down-regulation
CAMK_CAMK2_CAMK2D_ST	Q8WZ42	TTN	Q13557	CAMK2D	S22456	T22460N	22460	Missense	distal	4	no	50.123	51.212	EPSD	ICGC	37.605	Up-regulation
CAMK_CAMK2_CAMK2D_ST	Q8WZ42	TTN	Q13557	CAMK2D	S22456	A22458D	22458	Missense	proximal	2	no	50.123	56.554	EPSD	ICGC	37.605	Up-regulation
CAMK_CAMK2_CAMK2D_ST	Q8WZ42	TTN	Q13557	CAMK2D	S22456	G22457D	22457	Missense	proximal	1	no	50.123	45.198	EPSD	ICGC;COSMIC	37.605	Down-regulation
CAMK_CAMK2_CAMK2D_ST	Q8WZ42	TTN	Q13557	CAMK2D	S22456	S22451L	22451	Missense	distal	-5	no	50.123	49.385	EPSD	ICGC;COSMIC	37.605	Down-regulation
CAMK_CAMK2_CAMK2D_ST	Q8WZ42	TTN	Q13557	CAMK2D	S22456	D22455N	22455	Missense	proximal	-1	no	50.123	52.109	EPSD	ICGC;COSMIC	37.605	Up-regulation
CAMK_CAMK2_CAMK2D_ST	Q8WZ42	TTN	Q13557	CAMK2D	S22456	R22454M	22454	Missense	proximal	-2	no	50.123	49.893	EPSD	ICGC;COSMIC	37.605	Down-regulation
CAMK_CAMK2_CAMK2D_ST	Q8WZ42	TTN	Q13557	CAMK2D	S22525	V22532A	22532	Missense	distal	7	no	55.680	55.735	EPSD	ICGC;COSMIC	37.605	Up-regulation
CAMK_CAMK2_CAMK2D_ST	Q8WZ42	TTN	Q13557	CAMK2D	S22525	V22532L	22532	Missense	distal	7	no	55.680	56.320	EPSD	ICGC;COSMIC	37.605	Up-regulation
CAMK_CAMK2_CAMK2D_ST	Q8WZ42	TTN	Q13557	CAMK2D	S22525	R22526I	22526	Missense	proximal	1	no	55.680	57.251	EPSD	ICGC;COSMIC	37.605	Up-regulation
CAMK_CAMK2_CAMK2D_ST	Q8WZ42	TTN	Q13557	CAMK2D	S22525	K22521E	22521	Missense	distal	-4	no	55.680	52.426	EPSD	ICGC;COSMIC	37.605	Down-regulation
CAMK_CAMK2_CAMK2D_ST	Q8WZ42	TTN	Q13557	CAMK2D	S22525	N22531Y	22531	Missense	distal	6	no	55.680	54.063	EPSD	ICGC;COSMIC	37.605	Down-regulation
CAMK_CAMK2_CAMK2D_ST	Q8WZ42	TTN	Q13557	CAMK2D	S22534	V22538L	22538	Missense	distal	4	no	36.167	39.270	EPSD	ICGC;COSMIC	37.605	Gain
CAMK_CAMK2_CAMK2D_ST	Q8WZ42	TTN	Q13557	CAMK2D	S22853	G22846A	22846	Missense	distal	-7	no	38.703	41.383	EPSD	ICGC;COSMIC	37.605	Up-regulation
CAMK_CAMK2_CAMK2D_ST	Q8WZ42	TTN	Q13557	CAMK2D	S22853	S22853R	22853	Missense	central	0	yes	38.703	0.000	EPSD	ICGC;COSMIC	37.605	Loss
CAMK_CAMK2_CAMK2D_ST	Q8WZ42	TTN	Q13557	CAMK2D	T22878	D22877N	22877	Missense	proximal	-1	no	52.521	54.507	EPSD	ICGC;COSMIC	37.605	Up-regulation
CAMK_CAMK2_CAMK2D_ST	Q8WZ42	TTN	Q13557	CAMK2D	T22878	R22874T	22874	Missense	distal	-4	no	52.521	52.300	EPSD	ICGC;COSMIC	37.605	Down-regulation
CAMK_CAMK2_CAMK2D_ST	Q8WZ42	TTN	Q13557	CAMK2D	T22878	N22872D	22872	Missense	distal	-6	no	52.521	39.359	EPSD	ICGC;COSMIC	37.605	Down-regulation
CAMK_CAMK2_CAMK2D_ST	Q8WZ42	TTN	Q13557	CAMK2D	T22878	Q22883K	22883	Missense	distal	5	no	52.521	50.056	EPSD	ICGC;COSMIC	37.605	Down-regulation
CAMK_CAMK2_CAMK2D_ST	Q8WZ42	TTN	Q13557	CAMK2D	T22878	D22884N	22884	Missense	distal	6	no	52.521	54.617	EPSD	ICGC;COSMIC	37.605	Up-regulation
CAMK_CAMK2_CAMK2D_ST	Q8WZ42	TTN	Q13557	CAMK2D	T22878	P22881T	22881	Missense	distal	3	no	52.521	47.129	EPSD	ICGC;COSMIC	37.605	Down-regulation
CAMK_CAMK2_CAMK2D_ST	Q8WZ42	TTN	Q13557	CAMK2D	T22878	P22881R	22881	Missense	distal	3	no	52.521	52.137	EPSD	ICGC;COSMIC	37.605	Down-regulation
CAMK_CAMK2_CAMK2D_ST	Q8WZ42	TTN	Q13557	CAMK2D	S22926	R22922T	22922	Missense	distal	-4	no	39.403	39.182	EPSD	ICGC;COSMIC	37.605	Down-regulation
CAMK_CAMK2_CAMK2D_ST	Q8WZ42	TTN	Q13557	CAMK2D	S22926	R22922I	22922	Missense	distal	-4	no	39.403	37.828	EPSD	ICGC;COSMIC	37.605	Down-regulation
CAMK_CAMK2_CAMK2D_ST	Q8WZ42	TTN	Q13557	CAMK2D	S22926	K22923N	22923	Missense	distal	-3	no	39.403	31.112	EPSD	ICGC	37.605	Loss
CAMK_CAMK2_CAMK2D_ST	Q8WZ42	TTN	Q13557	CAMK2D	S22926	T22930P	22930	Missense	distal	4	no	39.403	40.509	EPSD	ICGC;COSMIC	37.605	Up-regulation
CAMK_CAMK2_CAMK2D_ST	Q8WZ42	TTN	Q13557	CAMK2D	S22926	C22932Y	22932	Missense	distal	6	no	39.403	38.707	EPSD	ICGC;COSMIC	37.605	Down-regulation
CAMK_CAMK2_CAMK2D_ST	Q8WZ42	TTN	Q13557	CAMK2D	S22969	R22975Q	22975	Missense	distal	6	no	40.024	42.575	EPSD	ICGC;COSMIC	37.605	Up-regulation
CAMK_CAMK2_CAMK2D_ST	Q8WZ42	TTN	Q13557	CAMK2D	S22969	A22967S	22967	Missense	proximal	-2	no	40.024	40.382	EPSD	ICGC	37.605	Up-regulation
CAMK_CAMK2_CAMK2D_ST	Q8WZ42	TTN	Q13557	CAMK2D	S22969	P22976H	22976	Missense	distal	7	no	40.024	40.287	EPSD	ICGC	37.605	Up-regulation
CAMK_CAMK2_CAMK2D_ST	Q8WZ42	TTN	Q13557	CAMK2D	S22969	L22962M	22962	Missense	distal	-7	no	40.024	39.097	EPSD	ICGC	37.605	Down-regulation
CAMK_CAMK2_CAMK2D_ST	Q8WZ42	TTN	Q13557	CAMK2D	S22969	P22963H	22963	Missense	distal	-6	no	40.024	41.298	EPSD	ICGC;COSMIC	37.605	Up-regulation
CAMK_CAMK2_CAMK2D_ST	Q8WZ42	TTN	Q13557	CAMK2D	S22969	A22967T	22967	Missense	proximal	-2	no	40.024	39.557	EPSD	ICGC;COSMIC	37.605	Down-regulation
CAMK_CAMK2_CAMK2D_ST	Q8WZ42	TTN	Q13557	CAMK2D	S22969	E22968D	22968	Missense	proximal	-1	no	40.024	37.668	EPSD	ICGC	37.605	Down-regulation
CAMK_CAMK2_CAMK2D_ST	Q8WZ42	TTN	Q13557	CAMK2D	S23063	D23070Y	23070	Missense	distal	7	no	38.882	39.255	EPSD	ICGC;COSMIC	37.605	Up-regulation
CAMK_CAMK2_CAMK2D_ST	Q8WZ42	TTN	Q13557	CAMK2D	S23063	R23060T	23060	Missense	distal	-3	no	38.882	17.251	EPSD	ICGC;COSMIC	37.605	Loss
CAMK_CAMK2_CAMK2D_ST	Q8WZ42	TTN	Q13557	CAMK2D	S23063	S23057N	23057	Missense	distal	-6	no	38.882	48.535	EPSD	ICGC;COSMIC	37.605	Up-regulation
CAMK_CAMK2_CAMK2D_ST	Q8WZ42	TTN	Q13557	CAMK2D	S23063	S23057G	23057	Missense	distal	-6	no	38.882	40.162	EPSD	ICGC;COSMIC	37.605	Up-regulation
CAMK_CAMK2_CAMK2D_ST	Q8WZ42	TTN	Q13557	CAMK2D	S23063	K23069N	23069	Missense	distal	6	no	38.882	39.780	EPSD	ICGC;COSMIC	37.605	Up-regulation
CAMK_CAMK2_CAMK2D_ST	Q8WZ42	TTN	Q13557	CAMK2D	S23063	A23068T	23068	Missense	distal	5	no	38.882	37.818	EPSD	ICGC;COSMIC	37.605	Down-regulation
CAMK_CAMK2_CAMK2D_ST	Q8WZ42	TTN	Q13557	CAMK2D	T23085	D23091H	23091	Missense	distal	6	no	38.198	40.531	EPSD	ICGC	37.605	Up-regulation
CAMK_CAMK2_CAMK2D_ST	Q8WZ42	TTN	Q13557	CAMK2D	T23085	D23091E	23091	Missense	distal	6	no	38.198	38.849	EPSD	ICGC;COSMIC	37.605	Up-regulation
CAMK_CAMK2_CAMK2D_ST	Q8WZ42	TTN	Q13557	CAMK2D	T23085	F23084V	23084	Missense	proximal	-1	no	38.198	41.232	EPSD	ICGC	37.605	Up-regulation
CAMK_CAMK2_CAMK2D_ST	Q8WZ42	TTN	Q13557	CAMK2D	T23214	R23208W	23208	Missense	distal	-6	no	46.872	38.525	EPSD	ICGC;COSMIC	37.605	Down-regulation
CAMK_CAMK2_CAMK2D_ST	Q8WZ42	TTN	Q13557	CAMK2D	T23214	A23220T	23220	Missense	distal	6	no	46.872	43.279	EPSD	ICGC	37.605	Down-regulation
CAMK_CAMK2_CAMK2D_ST	Q8WZ42	TTN	Q13557	CAMK2D	T23214	I23217N	23217	Missense	distal	3	no	46.872	55.299	EPSD	ICGC;COSMIC	37.605	Up-regulation
CAMK_CAMK2_CAMK2D_ST	Q8WZ42	TTN	Q13557	CAMK2D	T23214	R23208Q	23208	Missense	distal	-6	no	46.872	49.734	EPSD	ICGC;COSMIC	37.605	Up-regulation
CAMK_CAMK2_CAMK2D_ST	Q8WZ42	TTN	Q13557	CAMK2D	T23214	T23210S	23210	Missense	distal	-4	no	46.872	44.846	EPSD	ICGC;COSMIC	37.605	Down-regulation
CAMK_CAMK2_CAMK2D_ST	Q8WZ42	TTN	Q13557	CAMK2D	T23221	A23220T	23220	Missense	proximal	-1	no	40.243	41.898	EPSD	ICGC	37.605	Up-regulation
CAMK_CAMK2_CAMK2D_ST	Q8WZ42	TTN	Q13557	CAMK2D	T23221	I23217N	23217	Missense	distal	-4	no	40.243	36.693	EPSD	ICGC;COSMIC	37.605	Loss
CAMK_CAMK2_CAMK2D_ST	Q8WZ42	TTN	Q13557	CAMK2D	T23221	K23228N	23228	Missense	distal	7	no	40.243	39.784	EPSD	ICGC	37.605	Down-regulation
CAMK_CAMK2_CAMK2D_ST	Q8WZ42	TTN	Q13557	CAMK2D	T23234	C23230F	23230	Missense	distal	-4	no	48.833	46.453	EPSD	ICGC;COSMIC	37.605	Down-regulation
CAMK_CAMK2_CAMK2D_ST	Q8WZ42	TTN	Q13557	CAMK2D	T23234	K23228N	23228	Missense	distal	-6	no	48.833	57.799	EPSD	ICGC	37.605	Up-regulation
CAMK_CAMK2_CAMK2D_ST	Q8WZ42	TTN	Q13557	CAMK2D	T23252	G23249R	23249	Missense	distal	-3	no	13.345	56.302	EPSD	ICGC;COSMIC	37.605	Gain
CAMK_CAMK2_CAMK2D_ST	Q8WZ42	TTN	Q13557	CAMK2D	S23311	E23308K	23308	Missense	distal	-3	no	3.607	37.891	EPSD	ICGC;COSMIC	37.605	Gain
CAMK_CAMK2_CAMK2D_ST	Q8WZ42	TTN	Q13557	CAMK2D	T23555	E23551K	23551	Missense	distal	-4	no	42.732	45.987	EPSD	ICGC;COSMIC	37.605	Up-regulation
CAMK_CAMK2_CAMK2D_ST	Q8WZ42	TTN	Q13557	CAMK2D	T23555	L23561I	23561	Missense	distal	6	no	42.732	42.619	EPSD	ICGC	37.605	Down-regulation
CAMK_CAMK2_CAMK2D_ST	Q8WZ42	TTN	Q13557	CAMK2D	T23555	G23550V	23550	Missense	distal	-5	no	42.732	42.637	EPSD	ICGC;COSMIC;CCLE	37.605	Down-regulation
CAMK_CAMK2_CAMK2D_ST	Q8WZ42	TTN	Q13557	CAMK2D	T23555	G23550E	23550	Missense	distal	-5	no	42.732	42.146	EPSD	ICGC	37.605	Down-regulation
CAMK_CAMK2_CAMK2D_ST	Q8WZ42	TTN	Q13557	CAMK2D	T23620	N23617S	23617	Missense	distal	-3	no	39.475	43.000	EPSD	ICGC;COSMIC	37.605	Up-regulation
CAMK_CAMK2_CAMK2D_ST	Q8WZ42	TTN	Q13557	CAMK2D	T23620	Q23619P	23619	Missense	proximal	-1	no	39.475	38.017	EPSD	ICGC;COSMIC	37.605	Down-regulation
CAMK_CAMK2_CAMK2D_ST	Q8WZ42	TTN	Q13557	CAMK2D	T23620	A23616S	23616	Missense	distal	-4	no	39.475	37.865	EPSD	ICGC;COSMIC	37.605	Down-regulation
CAMK_CAMK2_CAMK2D_ST	Q8WZ42	TTN	Q13557	CAMK2D	T23620	T23626N	23626	Missense	distal	6	no	39.475	41.391	EPSD	ICGC;COSMIC	37.605	Up-regulation
CAMK_CAMK2_CAMK2D_ST	Q8WZ42	TTN	Q13557	CAMK2D	S24112	A24108V	24108	Missense	distal	-4	no	49.750	51.201	EPSD	ICGC;COSMIC	37.605	Up-regulation
CAMK_CAMK2_CAMK2D_ST	Q8WZ42	TTN	Q13557	CAMK2D	S24112	N24119S	24119	Missense	distal	7	no	49.750	48.562	EPSD	ICGC;COSMIC	37.605	Down-regulation
CAMK_CAMK2_CAMK2D_ST	Q8WZ42	TTN	Q13557	CAMK2D	S24112	Q24114K	24114	Missense	proximal	2	no	49.750	45.873	EPSD	ICGC	37.605	Down-regulation
CAMK_CAMK2_CAMK2D_ST	Q8WZ42	TTN	Q13557	CAMK2D	S24112	S24112F	24112	Missense	central	0	yes	49.750	0.000	EPSD	ICGC	37.605	Loss
CAMK_CAMK2_CAMK2D_ST	Q8WZ42	TTN	Q13557	CAMK2D	S24112	E24106K	24106	Missense	distal	-6	no	49.750	47.767	EPSD	ICGC;COSMIC	37.605	Down-regulation
CAMK_CAMK2_CAMK2D_ST	Q8WZ42	TTN	Q13557	CAMK2D	S24112	A24115V	24115	Missense	distal	3	no	49.750	28.518	EPSD	ICGC	37.605	Loss
CAMK_CAMK2_CAMK2D_ST	Q8WZ42	TTN	Q13557	CAMK2D	S24112	S24112Y	24112	Missense	central	0	yes	49.750	0.000	EPSD	ICGC;COSMIC	37.605	Loss
CAMK_CAMK2_CAMK2D_ST	Q8WZ42	TTN	Q13557	CAMK2D	S24112	R24109Q	24109	Missense	distal	-3	no	49.750	38.528	EPSD	ICGC;COSMIC	37.605	Down-regulation
CAMK_CAMK2_CAMK2D_ST	Q8WZ42	TTN	Q13557	CAMK2D	T24303	V24296I	24296	Missense	distal	-7	no	33.100	38.519	EPSD	ICGC	37.605	Gain
CAMK_CAMK2_CAMK2D_ST	Q8WZ42	TTN	Q13557	CAMK2D	T24307	R24306K	24306	Missense	proximal	-1	no	40.364	38.948	EPSD	ICGC;COSMIC	37.605	Down-regulation
CAMK_CAMK2_CAMK2D_ST	Q8WZ42	TTN	Q13557	CAMK2D	T24307	T24308I	24308	Missense	proximal	1	no	40.364	50.563	EPSD	ICGC;COSMIC	37.605	Up-regulation
CAMK_CAMK2_CAMK2D_ST	Q8WZ42	TTN	Q13557	CAMK2D	T24307	V24300I	24300	Missense	distal	-7	no	40.364	45.782	EPSD	ICGC;COSMIC	37.605	Up-regulation
CAMK_CAMK2_CAMK2D_ST	Q8WZ42	TTN	Q13557	CAMK2D	T24307	A24302D	24302	Missense	distal	-5	no	40.364	39.500	EPSD	ICGC	37.605	Down-regulation
CAMK_CAMK2_CAMK2D_ST	Q8WZ42	TTN	Q13557	CAMK2D	T24307	A24305V	24305	Missense	proximal	-2	no	40.364	40.637	EPSD	ICGC;COSMIC	37.605	Up-regulation
CAMK_CAMK2_CAMK2D_ST	Q8WZ42	TTN	Q13557	CAMK2D	T24307	S24301Y	24301	Missense	distal	-6	no	40.364	37.044	EPSD	ICGC	37.605	Loss
CAMK_CAMK2_CAMK2D_ST	Q8WZ42	TTN	Q13557	CAMK2D	T24316	G24317S	24317	Missense	proximal	1	no	41.697	40.226	EPSD	ICGC;COSMIC	37.605	Down-regulation
CAMK_CAMK2_CAMK2D_ST	Q8WZ42	TTN	Q13557	CAMK2D	S24393	E24390K	24390	Missense	distal	-3	no	5.886	40.170	EPSD	ICGC;COSMIC	37.605	Gain
CAMK_CAMK2_CAMK2D_ST	Q8WZ42	TTN	Q13557	CAMK2D	T24402	H24405N	24405	Missense	distal	3	no	33.205	43.298	EPSD	ICGC;COSMIC	37.605	Gain
CAMK_CAMK2_CAMK2D_ST	Q8WZ42	TTN	Q13557	CAMK2D	T24402	H24405Y	24405	Missense	distal	3	no	33.205	47.853	EPSD	ICGC	37.605	Gain
CAMK_CAMK2_CAMK2D_ST	Q8WZ42	TTN	Q13557	CAMK2D	T24453	P24450Q	24450	Missense	distal	-3	no	-20.487	37.720	EPSD	ICGC;COSMIC	37.605	Gain
CAMK_CAMK2_CAMK2D_ST	Q8WZ42	TTN	Q13557	CAMK2D	T24656	T24659A	24659	Missense	distal	3	no	28.410	41.537	EPSD	ICGC;COSMIC	37.605	Gain
CAMK_CAMK2_CAMK2D_ST	Q8WZ42	TTN	Q13557	CAMK2D	S24689	E24684Q	24684	Missense	distal	-5	no	52.555	51.138	EPSD	ICGC;COSMIC	37.605	Down-regulation
CAMK_CAMK2_CAMK2D_ST	Q8WZ42	TTN	Q13557	CAMK2D	S24689	R24690Q	24690	Missense	proximal	1	no	52.555	47.393	EPSD	ICGC;COSMIC;CCLE	37.605	Down-regulation
CAMK_CAMK2_CAMK2D_ST	Q8WZ42	TTN	Q13557	CAMK2D	S24689	R24686Q	24686	Missense	distal	-3	no	52.555	41.333	EPSD	ICGC;COSMIC	37.605	Down-regulation
CAMK_CAMK2_CAMK2D_ST	Q8WZ42	TTN	Q13557	CAMK2D	S24689	E24687K	24687	Missense	proximal	-2	no	52.555	52.793	EPSD	ICGC;COSMIC	37.605	Up-regulation
CAMK_CAMK2_CAMK2D_ST	Q8WZ42	TTN	Q13557	CAMK2D	S24689	T24688S	24688	Missense	proximal	-1	no	52.555	52.397	EPSD	ICGC;COSMIC	37.605	Down-regulation
CAMK_CAMK2_CAMK2D_ST	Q8WZ42	TTN	Q13557	CAMK2D	T24702	E24699K	24699	Missense	distal	-3	no	4.739	39.022	EPSD	ICGC;COSMIC	37.605	Gain
CAMK_CAMK2_CAMK2D_ST	Q8WZ42	TTN	Q13557	CAMK2D	S24788	I24781T	24781	Missense	distal	-7	no	42.938	39.371	EPSD	ICGC;COSMIC	37.605	Down-regulation
CAMK_CAMK2_CAMK2D_ST	Q8WZ42	TTN	Q13557	CAMK2D	S24788	D24786E	24786	Missense	proximal	-2	no	42.938	42.932	EPSD	ICGC;COSMIC	37.605	Down-regulation
CAMK_CAMK2_CAMK2D_ST	Q8WZ42	TTN	Q13557	CAMK2D	S24788	I24781N	24781	Missense	distal	-7	no	42.938	37.033	EPSD	ICGC;COSMIC	37.605	Loss
CAMK_CAMK2_CAMK2D_ST	Q8WZ42	TTN	Q13557	CAMK2D	S24788	D24786G	24786	Missense	proximal	-2	no	42.938	43.202	EPSD	ICGC;COSMIC	37.605	Up-regulation
CAMK_CAMK2_CAMK2D_ST	Q8WZ42	TTN	Q13557	CAMK2D	T24801	R24804H	24804	Missense	distal	3	no	48.512	38.965	EPSD	ICGC;COSMIC	37.605	Down-regulation
CAMK_CAMK2_CAMK2D_ST	Q8WZ42	TTN	Q13557	CAMK2D	T24801	T24801A	24801	Missense	central	0	yes	48.512	0.000	EPSD	ICGC;COSMIC	37.605	Loss
CAMK_CAMK2_CAMK2D_ST	Q8WZ42	TTN	Q13557	CAMK2D	T24801	L24805I	24805	Missense	distal	4	no	48.512	47.601	EPSD	ICGC;COSMIC	37.605	Down-regulation
CAMK_CAMK2_CAMK2D_ST	Q8WZ42	TTN	Q13557	CAMK2D	T24801	R24798H	24798	Missense	distal	-3	no	48.512	11.187	EPSD	ICGC;COSMIC;CCLE	37.605	Loss
CAMK_CAMK2_CAMK2D_ST	Q8WZ42	TTN	Q13557	CAMK2D	T24801	R24798C	24798	Missense	distal	-3	no	48.512	19.009	EPSD	ICGC;COSMIC;CCLE	37.605	Loss
CAMK_CAMK2_CAMK2D_ST	Q8WZ42	TTN	Q13557	CAMK2D	T24801	T24808I	24808	Missense	distal	7	no	48.512	47.917	EPSD	ICGC;COSMIC	37.605	Down-regulation
CAMK_CAMK2_CAMK2D_ST	Q8WZ42	TTN	Q13557	CAMK2D	T24808	L24805I	24805	Missense	distal	-3	no	33.639	42.371	EPSD	ICGC;COSMIC	37.605	Gain
CAMK_CAMK2_CAMK2D_ST	Q8WZ42	TTN	Q13557	CAMK2D	T24900	V24904I	24904	Missense	distal	4	no	36.032	38.225	EPSD	ICGC;COSMIC	37.605	Gain
CAMK_CAMK2_CAMK2D_ST	Q8WZ42	TTN	Q13557	CAMK2D	T24900	R24906Q	24906	Missense	distal	6	no	36.032	38.583	EPSD	ICGC;COSMIC	37.605	Gain
CAMK_CAMK2_CAMK2D_ST	Q8WZ42	TTN	Q13557	CAMK2D	S25094	Y25089H	25089	Missense	distal	-5	no	48.404	49.529	EPSD	ICGC;COSMIC	37.605	Up-regulation
CAMK_CAMK2_CAMK2D_ST	Q8WZ42	TTN	Q13557	CAMK2D	S25094	V25092L	25092	Missense	proximal	-2	no	48.404	48.113	EPSD	ICGC;COSMIC	37.605	Down-regulation
CAMK_CAMK2_CAMK2D_ST	Q8WZ42	TTN	Q13557	CAMK2D	S25094	V25092E	25092	Missense	proximal	-2	no	48.404	48.033	EPSD	ICGC;COSMIC	37.605	Down-regulation
CAMK_CAMK2_CAMK2D_ST	Q8WZ42	TTN	Q13557	CAMK2D	S25094	N25091I	25091	Missense	distal	-3	no	48.404	55.000	EPSD	ICGC	37.605	Up-regulation
CAMK_CAMK2_CAMK2D_ST	Q8WZ42	TTN	Q13557	CAMK2D	S25094	T25099A	25099	Missense	distal	5	no	48.404	49.469	EPSD	ICGC;COSMIC	37.605	Up-regulation
CAMK_CAMK2_CAMK2D_ST	Q8WZ42	TTN	Q13557	CAMK2D	T25389	T25385K	25385	Missense	distal	-4	no	41.908	40.906	EPSD	ICGC	37.605	Down-regulation
CAMK_CAMK2_CAMK2D_ST	Q8WZ42	TTN	Q13557	CAMK2D	T25389	S25383L	25383	Missense	distal	-6	no	41.908	34.607	EPSD	ICGC;COSMIC	37.605	Loss
CAMK_CAMK2_CAMK2D_ST	Q8WZ42	TTN	Q13557	CAMK2D	T25398	E25401G	25401	Missense	distal	3	no	38.862	30.948	EPSD	ICGC;COSMIC	37.605	Loss
CAMK_CAMK2_CAMK2D_ST	Q8WZ42	TTN	Q13557	CAMK2D	T25398	T25400K	25400	Missense	proximal	2	no	38.862	38.202	EPSD	ICGC	37.605	Down-regulation
CAMK_CAMK2_CAMK2D_ST	Q8WZ42	TTN	Q13557	CAMK2D	T25398	T25400M	25400	Missense	proximal	2	no	38.862	39.212	EPSD	ICGC;COSMIC	37.605	Up-regulation
CAMK_CAMK2_CAMK2D_ST	Q8WZ42	TTN	Q13557	CAMK2D	T25398	T25398A	25398	Missense	central	0	yes	38.862	0.000	EPSD	ICGC	37.605	Loss
CAMK_CAMK2_CAMK2D_ST	Q8WZ42	TTN	Q13557	CAMK2D	S25442	D25446Y	25446	Missense	distal	4	no	41.732	42.747	EPSD	ICGC;COSMIC	37.605	Up-regulation
CAMK_CAMK2_CAMK2D_ST	Q8WZ42	TTN	Q13557	CAMK2D	S25442	P25435R	25435	Missense	distal	-7	no	41.732	47.042	EPSD	ICGC;COSMIC	37.605	Up-regulation
CAMK_CAMK2_CAMK2D_ST	Q8WZ42	TTN	Q13557	CAMK2D	S25442	P25435H	25435	Missense	distal	-7	no	41.732	41.793	EPSD	ICGC;COSMIC	37.605	Up-regulation
CAMK_CAMK2_CAMK2D_ST	Q8WZ42	TTN	Q13557	CAMK2D	S25442	F25439S	25439	Missense	distal	-3	no	41.732	40.545	EPSD	ICGC;COSMIC	37.605	Down-regulation
CAMK_CAMK2_CAMK2D_ST	Q8WZ42	TTN	Q13557	CAMK2D	S25442	P25438S	25438	Missense	distal	-4	no	41.732	41.172	EPSD	ICGC;COSMIC	37.605	Down-regulation
CAMK_CAMK2_CAMK2D_ST	Q8WZ42	TTN	Q13557	CAMK2D	S25507	E25501Q	25501	Missense	distal	-6	no	36.196	39.485	EPSD	ICGC;COSMIC	37.605	Gain
CAMK_CAMK2_CAMK2D_ST	Q8WZ42	TTN	Q13557	CAMK2D	S25507	F25504V	25504	Missense	distal	-3	no	36.196	38.798	EPSD	ICGC;COSMIC	37.605	Gain
CAMK_CAMK2_CAMK2D_ST	Q8WZ42	TTN	Q13557	CAMK2D	S25617	F25613V	25613	Missense	distal	-4	no	43.639	48.956	EPSD	ICGC	37.605	Up-regulation
CAMK_CAMK2_CAMK2D_ST	Q8WZ42	TTN	Q13557	CAMK2D	S25617	A25622V	25622	Missense	distal	5	no	43.639	43.427	EPSD	ICGC;COSMIC	37.605	Down-regulation
CAMK_CAMK2_CAMK2D_ST	Q8WZ42	TTN	Q13557	CAMK2D	T25841	S25844Y	25844	Missense	distal	3	no	36.313	39.759	EPSD	ICGC;COSMIC	37.605	Gain
CAMK_CAMK2_CAMK2D_ST	Q8WZ42	TTN	Q13557	CAMK2D	T26133	L26132F	26132	Missense	proximal	-1	no	47.026	45.187	EPSD	ICGC;COSMIC	37.605	Down-regulation
CAMK_CAMK2_CAMK2D_ST	Q8WZ42	TTN	Q13557	CAMK2D	T26133	I26134V	26134	Missense	proximal	1	no	47.026	41.304	EPSD	ICGC;COSMIC	37.605	Down-regulation
CAMK_CAMK2_CAMK2D_ST	Q8WZ42	TTN	Q13557	CAMK2D	T26133	T26133N	26133	Missense	central	0	yes	47.026	0.000	EPSD	ICGC;COSMIC	37.605	Loss
CAMK_CAMK2_CAMK2D_ST	Q8WZ42	TTN	Q13557	CAMK2D	T26133	R26135K	26135	Missense	proximal	2	no	47.026	43.901	EPSD	ICGC	37.605	Down-regulation
CAMK_CAMK2_CAMK2D_ST	Q8WZ42	TTN	Q13557	CAMK2D	T26133	S26127G	26127	Missense	distal	-6	no	47.026	48.307	EPSD	ICGC;COSMIC	37.605	Up-regulation
CAMK_CAMK2_CAMK2D_ST	Q8WZ42	TTN	Q13557	CAMK2D	T26366	N26369D	26369	Missense	distal	3	no	39.278	30.850	EPSD	ICGC;COSMIC	37.605	Loss
CAMK_CAMK2_CAMK2D_ST	Q8WZ42	TTN	Q13557	CAMK2D	T26480	R26487C	26487	Missense	distal	7	no	51.713	53.533	EPSD	ICGC;COSMIC	37.605	Up-regulation
CAMK_CAMK2_CAMK2D_ST	Q8WZ42	TTN	Q13557	CAMK2D	T26480	L26478P	26478	Missense	proximal	-2	no	51.713	52.186	EPSD	ICGC	37.605	Up-regulation
CAMK_CAMK2_CAMK2D_ST	Q8WZ42	TTN	Q13557	CAMK2D	T26480	R26477H	26477	Missense	distal	-3	no	51.713	14.389	EPSD	ICGC;COSMIC	37.605	Loss
CAMK_CAMK2_CAMK2D_ST	Q8WZ42	TTN	Q13557	CAMK2D	T26480	E26483K	26483	Missense	distal	3	no	51.713	45.694	EPSD	ICGC;COSMIC	37.605	Down-regulation
CAMK_CAMK2_CAMK2D_ST	Q8WZ42	TTN	Q13557	CAMK2D	S26557	E26554K	26554	Missense	distal	-3	no	7.524	41.808	EPSD	ICGC;COSMIC	37.605	Gain
CAMK_CAMK2_CAMK2D_ST	Q8WZ42	TTN	Q13557	CAMK2D	T26784	D26778H	26778	Missense	distal	-6	no	41.023	45.454	EPSD	ICGC;COSMIC	37.605	Up-regulation
CAMK_CAMK2_CAMK2D_ST	Q8WZ42	TTN	Q13557	CAMK2D	T26784	Q26786K	26786	Missense	proximal	2	no	41.023	37.145	EPSD	ICGC	37.605	Loss
CAMK_CAMK2_CAMK2D_ST	Q8WZ42	TTN	Q13557	CAMK2D	T26784	G26785V	26785	Missense	proximal	1	no	41.023	41.626	EPSD	ICGC	37.605	Up-regulation
CAMK_CAMK2_CAMK2D_ST	Q8WZ42	TTN	Q13557	CAMK2D	T26784	R26782L	26782	Missense	proximal	-2	no	41.023	40.115	EPSD	ICGC;COSMIC	37.605	Down-regulation
CAMK_CAMK2_CAMK2D_ST	Q8WZ42	TTN	Q13557	CAMK2D	T26784	R26782Q	26782	Missense	proximal	-2	no	41.023	40.504	EPSD	ICGC	37.605	Down-regulation
CAMK_CAMK2_CAMK2D_ST	Q8WZ42	TTN	Q13557	CAMK2D	T26972	K26970Q	26970	Missense	proximal	-2	no	54.033	54.264	EPSD	ICGC	37.605	Up-regulation
CAMK_CAMK2_CAMK2D_ST	Q8WZ42	TTN	Q13557	CAMK2D	T26972	R26968S	26968	Missense	distal	-4	no	54.033	51.787	EPSD	ICGC;COSMIC	37.605	Down-regulation
CAMK_CAMK2_CAMK2D_ST	Q8WZ42	TTN	Q13557	CAMK2D	T26972	E26979K	26979	Missense	distal	7	no	54.033	54.111	EPSD	ICGC;COSMIC	37.605	Up-regulation
CAMK_CAMK2_CAMK2D_ST	Q8WZ42	TTN	Q13557	CAMK2D	T26972	R26975W	26975	Missense	distal	3	no	54.033	41.934	EPSD	ICGC;COSMIC	37.605	Down-regulation
CAMK_CAMK2_CAMK2D_ST	Q8WZ42	TTN	Q13557	CAMK2D	S27012	D27006N	27006	Missense	distal	-6	no	27.446	40.608	EPSD	ICGC	37.605	Gain
CAMK_CAMK2_CAMK2D_ST	Q8WZ42	TTN	Q13557	CAMK2D	S27060	W27057L	27057	Missense	distal	-3	no	20.596	39.797	EPSD	ICGC;COSMIC	37.605	Gain
CAMK_CAMK2_CAMK2D_ST	Q8WZ42	TTN	Q13557	CAMK2D	T27217	E27219Q	27219	Missense	proximal	2	no	48.964	48.525	EPSD	ICGC;COSMIC	37.605	Down-regulation
CAMK_CAMK2_CAMK2D_ST	Q8WZ42	TTN	Q13557	CAMK2D	T27217	V27222M	27222	Missense	distal	5	no	48.964	45.625	EPSD	ICGC	37.605	Down-regulation
CAMK_CAMK2_CAMK2D_ST	Q8WZ42	TTN	Q13557	CAMK2D	T27217	Q27214H	27214	Missense	distal	-3	no	48.964	22.862	EPSD	ICGC;COSMIC	37.605	Loss
CAMK_CAMK2_CAMK2D_ST	Q8WZ42	TTN	Q13557	CAMK2D	T27217	T27212N	27212	Missense	distal	-5	no	48.964	49.227	EPSD	ICGC;COSMIC	37.605	Up-regulation
CAMK_CAMK2_CAMK2D_ST	Q8WZ42	TTN	Q13557	CAMK2D	S27428	P27433T	27433	Missense	distal	5	no	37.983	36.235	EPSD	ICGC	37.605	Loss
CAMK_CAMK2_CAMK2D_ST	Q8WZ42	TTN	Q13557	CAMK2D	S27428	D27424G	27424	Missense	distal	-4	no	37.983	39.770	EPSD	ICGC	37.605	Up-regulation
CAMK_CAMK2_CAMK2D_ST	Q8WZ42	TTN	Q13557	CAMK2D	S27428	G27429E	27429	Missense	proximal	1	no	37.983	36.985	EPSD	ICGC;COSMIC	37.605	Loss
CAMK_CAMK2_CAMK2D_ST	Q8WZ42	TTN	Q13557	CAMK2D	S27428	V27435A	27435	Missense	distal	7	no	37.983	38.037	EPSD	ICGC	37.605	Up-regulation
CAMK_CAMK2_CAMK2D_ST	Q8WZ42	TTN	Q13557	CAMK2D	T27554	K27560Q	27560	Missense	distal	6	no	34.532	37.736	EPSD	ICGC;COSMIC	37.605	Gain
CAMK_CAMK2_CAMK2D_ST	Q8WZ42	TTN	Q13557	CAMK2D	T27562	G27564E	27564	Missense	proximal	2	no	44.653	42.958	EPSD	ICGC	37.605	Down-regulation
CAMK_CAMK2_CAMK2D_ST	Q8WZ42	TTN	Q13557	CAMK2D	T27562	M27559I	27559	Missense	distal	-3	no	44.653	41.914	EPSD	ICGC;COSMIC	37.605	Down-regulation
CAMK_CAMK2_CAMK2D_ST	Q8WZ42	TTN	Q13557	CAMK2D	T27562	M27555I	27555	Missense	distal	-7	no	44.653	45.007	EPSD	ICGC;COSMIC	37.605	Up-regulation
CAMK_CAMK2_CAMK2D_ST	Q8WZ42	TTN	Q13557	CAMK2D	T27562	K27560Q	27560	Missense	proximal	-2	no	44.653	44.884	EPSD	ICGC;COSMIC	37.605	Up-regulation
CAMK_CAMK2_CAMK2D_ST	Q8WZ42	TTN	Q13557	CAMK2D	T27562	V27558A	27558	Missense	distal	-4	no	44.653	43.202	EPSD	ICGC;COSMIC	37.605	Down-regulation
CAMK_CAMK2_CAMK2D_ST	Q8WZ42	TTN	Q13557	CAMK2D	T27659	R27652C	27652	Missense	distal	-7	no	45.960	47.679	EPSD	ICGC;COSMIC	37.605	Up-regulation
CAMK_CAMK2_CAMK2D_ST	Q8WZ42	TTN	Q13557	CAMK2D	T27659	R27652H	27652	Missense	distal	-7	no	45.960	40.711	EPSD	ICGC;COSMIC	37.605	Down-regulation
CAMK_CAMK2_CAMK2D_ST	Q8WZ42	TTN	Q13557	CAMK2D	T27659	G27664E	27664	Missense	distal	5	no	45.960	44.532	EPSD	ICGC;COSMIC	37.605	Down-regulation
CAMK_CAMK2_CAMK2D_ST	Q8WZ42	TTN	Q13557	CAMK2D	T27659	S27662N	27662	Missense	distal	3	no	45.960	44.850	EPSD	ICGC	37.605	Down-regulation
CAMK_CAMK2_CAMK2D_ST	Q8WZ42	TTN	Q13557	CAMK2D	T27660	G27664E	27664	Missense	distal	4	no	48.131	48.397	EPSD	ICGC;COSMIC	37.605	Up-regulation
CAMK_CAMK2_CAMK2D_ST	Q8WZ42	TTN	Q13557	CAMK2D	T27660	Y27667C	27667	Missense	distal	7	no	48.131	47.818	EPSD	ICGC;COSMIC	37.605	Down-regulation
CAMK_CAMK2_CAMK2D_ST	Q8WZ42	TTN	Q13557	CAMK2D	T27660	S27662N	27662	Missense	proximal	2	no	48.131	44.517	EPSD	ICGC	37.605	Down-regulation
CAMK_CAMK2_CAMK2D_ST	Q8WZ42	TTN	Q13557	CAMK2D	S27757	L27759F	27759	Missense	proximal	2	no	39.512	31.867	EPSD	ICGC;COSMIC	37.605	Loss
CAMK_CAMK2_CAMK2D_ST	Q8WZ42	TTN	Q13557	CAMK2D	S27757	I27755T	27755	Missense	proximal	-2	no	39.512	38.533	EPSD	ICGC;COSMIC	37.605	Down-regulation
CAMK_CAMK2_CAMK2D_ST	Q8WZ42	TTN	Q13557	CAMK2D	S27757	I27755V	27755	Missense	proximal	-2	no	39.512	39.275	EPSD	ICGC;COSMIC	37.605	Down-regulation
CAMK_CAMK2_CAMK2D_ST	Q8WZ42	TTN	Q13557	CAMK2D	S27757	L27759S	27759	Missense	proximal	2	no	39.512	38.063	EPSD	ICGC;COSMIC	37.605	Down-regulation
CAMK_CAMK2_CAMK2D_ST	Q8WZ42	TTN	Q13557	CAMK2D	T28046	D28049E	28049	Missense	distal	3	no	25.104	37.689	EPSD	ICGC;COSMIC	37.605	Gain
CAMK_CAMK2_CAMK2D_ST	Q8WZ42	TTN	Q13557	CAMK2D	T28055	V28054I	28054	Missense	proximal	-1	no	43.336	42.772	EPSD	ICGC;COSMIC	37.605	Down-regulation
CAMK_CAMK2_CAMK2D_ST	Q8WZ42	TTN	Q13557	CAMK2D	T28055	R28048H	28048	Missense	distal	-7	no	43.336	38.087	EPSD	ICGC;COSMIC	37.605	Down-regulation
CAMK_CAMK2_CAMK2D_ST	Q8WZ42	TTN	Q13557	CAMK2D	T28055	L28057F	28057	Missense	proximal	2	no	43.336	35.692	EPSD	ICGC	37.605	Loss
CAMK_CAMK2_CAMK2D_ST	Q8WZ42	TTN	Q13557	CAMK2D	T28055	R28048S	28048	Missense	distal	-7	no	43.336	41.278	EPSD	ICGC	37.605	Down-regulation
CAMK_CAMK2_CAMK2D_ST	Q8WZ42	TTN	Q13557	CAMK2D	T28055	R28051T	28051	Missense	distal	-4	no	43.336	43.116	EPSD	ICGC;COSMIC	37.605	Down-regulation
CAMK_CAMK2_CAMK2D_ST	Q8WZ42	TTN	Q13557	CAMK2D	T28055	D28049E	28049	Missense	distal	-6	no	43.336	49.516	EPSD	ICGC;COSMIC	37.605	Up-regulation
CAMK_CAMK2_CAMK2D_ST	Q8WZ42	TTN	Q13557	CAMK2D	T28055	R28048C	28048	Missense	distal	-7	no	43.336	45.055	EPSD	ICGC;COSMIC	37.605	Up-regulation
CAMK_CAMK2_CAMK2D_ST	Q8WZ42	TTN	Q13557	CAMK2D	T28145	S28144F	28144	Missense	proximal	-1	no	41.140	37.868	EPSD	ICGC;COSMIC	37.605	Down-regulation
CAMK_CAMK2_CAMK2D_ST	Q8WZ42	TTN	Q13557	CAMK2D	T28145	G28147R	28147	Missense	proximal	2	no	41.140	38.254	EPSD	ICGC;COSMIC	37.605	Down-regulation
CAMK_CAMK2_CAMK2D_ST	Q8WZ42	TTN	Q13557	CAMK2D	T28145	W28140L	28140	Missense	distal	-5	no	41.140	39.415	EPSD	ICGC;COSMIC	37.605	Down-regulation
CAMK_CAMK2_CAMK2D_ST	Q8WZ42	TTN	Q13557	CAMK2D	T28338	R28337I	28337	Missense	proximal	-1	no	38.158	36.203	EPSD	ICGC;COSMIC	37.605	Loss
CAMK_CAMK2_CAMK2D_ST	Q8WZ42	TTN	Q13557	CAMK2D	T28338	V28342M	28342	Missense	distal	4	no	38.158	40.060	EPSD	ICGC	37.605	Up-regulation
CAMK_CAMK2_CAMK2D_ST	Q8WZ42	TTN	Q13557	CAMK2D	T28338	A28334G	28334	Missense	distal	-4	no	38.158	36.495	EPSD	ICGC;COSMIC	37.605	Loss
CAMK_CAMK2_CAMK2D_ST	Q8WZ42	TTN	Q13557	CAMK2D	T28338	A28334T	28334	Missense	distal	-4	no	38.158	38.574	EPSD	ICGC;COSMIC	37.605	Up-regulation
CAMK_CAMK2_CAMK2D_ST	Q8WZ42	TTN	Q13557	CAMK2D	T28338	K28331T	28331	Missense	distal	-7	no	38.158	33.710	EPSD	ICGC;COSMIC	37.605	Loss
CAMK_CAMK2_CAMK2D_ST	Q8WZ42	TTN	Q13557	CAMK2D	T28338	K28345T	28345	Missense	distal	7	no	38.158	38.608	EPSD	ICGC;COSMIC	37.605	Up-regulation
CAMK_CAMK2_CAMK2D_ST	Q8WZ42	TTN	Q13557	CAMK2D	S28397	R28394C	28394	Missense	distal	-3	no	51.215	21.713	EPSD	ICGC;COSMIC	37.605	Loss
CAMK_CAMK2_CAMK2D_ST	Q8WZ42	TTN	Q13557	CAMK2D	S28397	S28397L	28397	Missense	central	0	yes	51.215	0.000	EPSD	ICGC;COSMIC	37.605	Loss
CAMK_CAMK2_CAMK2D_ST	Q8WZ42	TTN	Q13557	CAMK2D	S28397	R28394S	28394	Missense	distal	-3	no	51.215	35.041	EPSD	ICGC	37.605	Loss
CAMK_CAMK2_CAMK2D_ST	Q8WZ42	TTN	Q13557	CAMK2D	S28450	T28444A	28444	Missense	distal	-6	no	34.399	38.659	EPSD	ICGC;COSMIC	37.605	Gain
CAMK_CAMK2_CAMK2D_ST	Q8WZ42	TTN	Q13557	CAMK2D	S28450	E28446K	28446	Missense	distal	-4	no	34.399	37.654	EPSD	ICGC;COSMIC	37.605	Gain
CAMK_CAMK2_CAMK2D_ST	Q8WZ42	TTN	Q13557	CAMK2D	S28456	R28461T	28461	Missense	distal	5	no	53.062	53.749	EPSD	ICGC;COSMIC	37.605	Up-regulation
CAMK_CAMK2_CAMK2D_ST	Q8WZ42	TTN	Q13557	CAMK2D	S28456	L28452P	28452	Missense	distal	-4	no	53.062	54.625	EPSD	ICGC	37.605	Up-regulation
CAMK_CAMK2_CAMK2D_ST	Q8WZ42	TTN	Q13557	CAMK2D	S28456	V28462A	28462	Missense	distal	6	no	53.062	54.831	EPSD	ICGC;COSMIC	37.605	Up-regulation
CAMK_CAMK2_CAMK2D_ST	Q8WZ42	TTN	Q13557	CAMK2D	T28577	V28578F	28578	Missense	proximal	1	no	34.495	40.880	EPSD	ICGC	37.605	Gain
CAMK_CAMK2_CAMK2D_ST	Q8WZ42	TTN	Q13557	CAMK2D	S28636	R28640I	28640	Missense	distal	4	no	44.404	44.373	EPSD	ICGC;COSMIC	37.605	Down-regulation
CAMK_CAMK2_CAMK2D_ST	Q8WZ42	TTN	Q13557	CAMK2D	S28636	T28629N	28629	Missense	distal	-7	no	44.404	42.066	EPSD	ICGC;COSMIC	37.605	Down-regulation
CAMK_CAMK2_CAMK2D_ST	Q8WZ42	TTN	Q13557	CAMK2D	S28736	S28739C	28739	Missense	distal	3	no	41.916	42.952	EPSD	ICGC	37.605	Up-regulation
CAMK_CAMK2_CAMK2D_ST	Q8WZ42	TTN	Q13557	CAMK2D	S28736	S28739F	28739	Missense	distal	3	no	41.916	36.093	EPSD	ICGC	37.605	Loss
CAMK_CAMK2_CAMK2D_ST	Q8WZ42	TTN	Q13557	CAMK2D	S28736	N28734I	28734	Missense	proximal	-2	no	41.916	41.810	EPSD	ICGC	37.605	Down-regulation
CAMK_CAMK2_CAMK2D_ST	Q8WZ42	TTN	Q13557	CAMK2D	S28736	V28733I	28733	Missense	distal	-3	no	41.916	41.197	EPSD	ICGC;COSMIC	37.605	Down-regulation
CAMK_CAMK2_CAMK2D_ST	Q8WZ42	TTN	Q13557	CAMK2D	S28739	S28739C	28739	Missense	central	0	yes	47.743	0.000	EPSD	ICGC	37.605	Loss
CAMK_CAMK2_CAMK2D_ST	Q8WZ42	TTN	Q13557	CAMK2D	S28739	S28739F	28739	Missense	central	0	yes	47.743	0.000	EPSD	ICGC	37.605	Loss
CAMK_CAMK2_CAMK2D_ST	Q8WZ42	TTN	Q13557	CAMK2D	S28739	N28734I	28734	Missense	distal	-5	no	47.743	46.320	EPSD	ICGC	37.605	Down-regulation
CAMK_CAMK2_CAMK2D_ST	Q8WZ42	TTN	Q13557	CAMK2D	S28739	V28733I	28733	Missense	distal	-6	no	47.743	49.008	EPSD	ICGC;COSMIC	37.605	Up-regulation
CAMK_CAMK2_CAMK2D_ST	Q8WZ42	TTN	Q13557	CAMK2D	S28770	S28767R	28767	Missense	distal	-3	no	21.494	37.667	EPSD	ICGC;COSMIC	37.605	Gain
CAMK_CAMK2_CAMK2D_ST	Q8WZ42	TTN	Q13557	CAMK2D	T29039	G29046D	29046	Missense	distal	7	no	45.289	46.280	EPSD	ICGC;COSMIC	37.605	Up-regulation
CAMK_CAMK2_CAMK2D_ST	Q8WZ42	TTN	Q13557	CAMK2D	T29039	C29033R	29033	Missense	distal	-6	no	45.289	48.160	EPSD	ICGC;COSMIC	37.605	Up-regulation
CAMK_CAMK2_CAMK2D_ST	Q8WZ42	TTN	Q13557	CAMK2D	T29039	G29046S	29046	Missense	distal	7	no	45.289	44.361	EPSD	ICGC;COSMIC	37.605	Down-regulation
CAMK_CAMK2_CAMK2D_ST	Q8WZ42	TTN	Q13557	CAMK2D	T29039	G29046A	29046	Missense	distal	7	no	45.289	45.661	EPSD	ICGC;COSMIC	37.605	Up-regulation
CAMK_CAMK2_CAMK2D_ST	Q8WZ42	TTN	Q13557	CAMK2D	T29039	K29042R	29042	Missense	distal	3	no	45.289	46.605	EPSD	ICGC;COSMIC	37.605	Up-regulation
CAMK_CAMK2_CAMK2D_ST	Q8WZ42	TTN	Q13557	CAMK2D	T29039	G29046C	29046	Missense	distal	7	no	45.289	46.339	EPSD	ICGC;COSMIC	37.605	Up-regulation
CAMK_CAMK2_CAMK2D_ST	Q8WZ42	TTN	Q13557	CAMK2D	T29039	N29045S	29045	Missense	distal	6	no	45.289	44.004	EPSD	ICGC;COSMIC	37.605	Down-regulation
CAMK_CAMK2_CAMK2D_ST	Q8WZ42	TTN	Q13557	CAMK2D	S29421	R29419H	29419	Missense	proximal	-2	no	41.183	40.291	EPSD	ICGC;COSMIC	37.605	Down-regulation
CAMK_CAMK2_CAMK2D_ST	Q8WZ42	TTN	Q13557	CAMK2D	S29421	S29426N	29426	Missense	distal	5	no	41.183	41.680	EPSD	ICGC;COSMIC	37.605	Up-regulation
CAMK_CAMK2_CAMK2D_ST	Q8WZ42	TTN	Q13557	CAMK2D	S29421	A29417S	29417	Missense	distal	-4	no	41.183	39.573	EPSD	ICGC;COSMIC	37.605	Down-regulation
CAMK_CAMK2_CAMK2D_ST	Q8WZ42	TTN	Q13557	CAMK2D	S29421	R29420H	29420	Missense	proximal	-1	no	41.183	36.705	EPSD	ICGC;COSMIC	37.605	Loss
CAMK_CAMK2_CAMK2D_ST	Q8WZ42	TTN	Q13557	CAMK2D	S29421	R29420S	29420	Missense	proximal	-1	no	41.183	40.030	EPSD	ICGC;COSMIC	37.605	Down-regulation
CAMK_CAMK2_CAMK2D_ST	Q8WZ42	TTN	Q13557	CAMK2D	S29421	R29415Q	29415	Missense	distal	-6	no	41.183	44.045	EPSD	ICGC;COSMIC	37.605	Up-regulation
CAMK_CAMK2_CAMK2D_ST	Q8WZ42	TTN	Q13557	CAMK2D	T29539	E29540K	29540	Missense	proximal	1	no	46.173	46.648	EPSD	ICGC;COSMIC	37.605	Up-regulation
CAMK_CAMK2_CAMK2D_ST	Q8WZ42	TTN	Q13557	CAMK2D	T29539	V29536A	29536	Missense	distal	-3	no	46.173	32.601	EPSD	ICGC	37.605	Loss
CAMK_CAMK2_CAMK2D_ST	Q8WZ42	TTN	Q13557	CAMK2D	T29539	R29534C	29534	Missense	distal	-5	no	46.173	46.473	EPSD	ICGC;COSMIC	37.605	Up-regulation
CAMK_CAMK2_CAMK2D_ST	Q8WZ42	TTN	Q13557	CAMK2D	T29539	R29544H	29544	Missense	distal	5	no	46.173	46.976	EPSD	ICGC;COSMIC	37.605	Up-regulation
CAMK_CAMK2_CAMK2D_ST	Q8WZ42	TTN	Q13557	CAMK2D	T29539	E29542K	29542	Missense	distal	3	no	46.173	40.154	EPSD	ICGC;COSMIC	37.605	Down-regulation
CAMK_CAMK2_CAMK2D_ST	Q8WZ42	TTN	Q13557	CAMK2D	T29539	R29534S	29534	Missense	distal	-5	no	46.173	47.123	EPSD	ICGC	37.605	Up-regulation
CAMK_CAMK2_CAMK2D_ST	Q8WZ42	TTN	Q13557	CAMK2D	T29539	V29545A	29545	Missense	distal	6	no	46.173	47.942	EPSD	ICGC;COSMIC	37.605	Up-regulation
CAMK_CAMK2_CAMK2D_ST	Q8WZ42	TTN	Q13557	CAMK2D	T29539	L29535R	29535	Missense	distal	-4	no	46.173	49.422	EPSD	ICGC;COSMIC	37.605	Up-regulation
CAMK_CAMK2_CAMK2D_ST	Q8WZ42	TTN	Q13557	CAMK2D	S29562	A29559V	29559	Missense	distal	-3	no	25.010	38.583	EPSD	ICGC;COSMIC	37.605	Gain
CAMK_CAMK2_CAMK2D_ST	Q8WZ42	TTN	Q13557	CAMK2D	T29593	S29599R	29599	Missense	distal	6	no	46.868	47.909	EPSD	ICGC;COSMIC	37.605	Up-regulation
CAMK_CAMK2_CAMK2D_ST	Q8WZ42	TTN	Q13557	CAMK2D	T29593	P29597T	29597	Missense	distal	4	no	46.868	45.762	EPSD	ICGC	37.605	Down-regulation
CAMK_CAMK2_CAMK2D_ST	Q8WZ42	TTN	Q13557	CAMK2D	T29593	I29594T	29594	Missense	proximal	1	no	46.868	36.669	EPSD	ICGC;COSMIC	37.605	Loss
CAMK_CAMK2_CAMK2D_ST	Q8WZ42	TTN	Q13557	CAMK2D	T29593	D29595G	29595	Missense	proximal	2	no	46.868	41.138	EPSD	ICGC;COSMIC	37.605	Down-regulation
CAMK_CAMK2_CAMK2D_ST	Q8WZ42	TTN	Q13557	CAMK2D	S29599	I29594T	29594	Missense	distal	-5	no	36.469	37.629	EPSD	ICGC;COSMIC	37.605	Gain
CAMK_CAMK2_CAMK2D_ST	Q8WZ42	TTN	Q13557	CAMK2D	S29599	T29593S	29593	Missense	distal	-6	no	36.469	39.441	EPSD	ICGC;COSMIC	37.605	Gain
CAMK_CAMK2_CAMK2D_ST	Q8WZ42	TTN	Q13557	CAMK2D	S29599	D29595G	29595	Missense	distal	-4	no	36.469	38.256	EPSD	ICGC;COSMIC	37.605	Gain
CAMK_CAMK2_CAMK2D_ST	Q8WZ42	TTN	Q13557	CAMK2D	T29626	V29621M	29621	Missense	distal	-5	no	54.274	53.574	EPSD	ICGC;COSMIC	37.605	Down-regulation
CAMK_CAMK2_CAMK2D_ST	Q8WZ42	TTN	Q13557	CAMK2D	T29626	V29621E	29621	Missense	distal	-5	no	54.274	53.782	EPSD	ICGC;COSMIC	37.605	Down-regulation
CAMK_CAMK2_CAMK2D_ST	Q8WZ42	TTN	Q13557	CAMK2D	S29637	D29636Y	29636	Missense	proximal	-1	no	37.671	39.186	EPSD	ICGC;COSMIC	37.605	Up-regulation
CAMK_CAMK2_CAMK2D_ST	Q8WZ42	TTN	Q13557	CAMK2D	S29642	D29636Y	29636	Missense	distal	-6	no	38.980	39.170	EPSD	ICGC;COSMIC	37.605	Up-regulation
CAMK_CAMK2_CAMK2D_ST	Q8WZ42	TTN	Q13557	CAMK2D	S29720	Q29726E	29726	Missense	distal	6	no	45.048	41.296	EPSD	ICGC;COSMIC	37.605	Down-regulation
CAMK_CAMK2_CAMK2D_ST	Q8WZ42	TTN	Q13557	CAMK2D	S29720	K29723E	29723	Missense	distal	3	no	45.048	51.067	EPSD	ICGC;COSMIC	37.605	Up-regulation
CAMK_CAMK2_CAMK2D_ST	Q8WZ42	TTN	Q13557	CAMK2D	S29720	R29724H	29724	Missense	distal	4	no	45.048	43.475	EPSD	ICGC;COSMIC	37.605	Down-regulation
CAMK_CAMK2_CAMK2D_ST	Q8WZ42	TTN	Q13557	CAMK2D	T29725	Q29726E	29726	Missense	proximal	1	no	38.274	37.685	EPSD	ICGC;COSMIC	37.605	Down-regulation
CAMK_CAMK2_CAMK2D_ST	Q8WZ42	TTN	Q13557	CAMK2D	T29725	L29732I	29732	Missense	distal	7	no	38.274	37.892	EPSD	ICGC;COSMIC	37.605	Down-regulation
CAMK_CAMK2_CAMK2D_ST	Q8WZ42	TTN	Q13557	CAMK2D	T29725	K29723E	29723	Missense	proximal	-2	no	38.274	38.037	EPSD	ICGC;COSMIC	37.605	Down-regulation
CAMK_CAMK2_CAMK2D_ST	Q8WZ42	TTN	Q13557	CAMK2D	T29725	R29724H	29724	Missense	proximal	-1	no	38.274	33.796	EPSD	ICGC;COSMIC	37.605	Loss
CAMK_CAMK2_CAMK2D_ST	Q8WZ42	TTN	Q13557	CAMK2D	S29990	I29986N	29986	Missense	distal	-4	no	38.563	35.013	EPSD	ICGC;COSMIC	37.605	Loss
CAMK_CAMK2_CAMK2D_ST	Q8WZ42	TTN	Q13557	CAMK2D	S29990	A29996D	29996	Missense	distal	6	no	38.563	34.790	EPSD	ICGC;COSMIC	37.605	Loss
CAMK_CAMK2_CAMK2D_ST	Q8WZ42	TTN	Q13557	CAMK2D	S29990	D29995N	29995	Missense	distal	5	no	38.563	40.644	EPSD	ICGC;COSMIC	37.605	Up-regulation
CAMK_CAMK2_CAMK2D_ST	Q8WZ42	TTN	Q13557	CAMK2D	S29990	L29983M	29983	Missense	distal	-7	no	38.563	37.636	EPSD	ICGC;COSMIC	37.605	Down-regulation
CAMK_CAMK2_CAMK2D_ST	Q8WZ42	TTN	Q13557	CAMK2D	T30080	S30077R	30077	Missense	distal	-3	no	32.231	48.405	EPSD	ICGC;COSMIC	37.605	Gain
CAMK_CAMK2_CAMK2D_ST	Q8WZ42	TTN	Q13557	CAMK2D	T30080	L30074P	30074	Missense	distal	-6	no	32.231	39.181	EPSD	ICGC;COSMIC	37.605	Gain
CAMK_CAMK2_CAMK2D_ST	Q8WZ42	TTN	Q13557	CAMK2D	T30225	Y30223C	30223	Missense	proximal	-2	no	37.655	37.915	EPSD	ICGC;COSMIC	37.605	Up-regulation
CAMK_CAMK2_CAMK2D_ST	Q8WZ42	TTN	Q13557	CAMK2D	T30320	R30317Q	30317	Missense	distal	-3	no	51.220	39.997	EPSD	ICGC	37.605	Down-regulation
CAMK_CAMK2_CAMK2D_ST	Q8WZ42	TTN	Q13557	CAMK2D	T30320	N30321Y	30321	Missense	proximal	1	no	51.220	47.413	EPSD	ICGC;COSMIC	37.605	Down-regulation
CAMK_CAMK2_CAMK2D_ST	Q8WZ42	TTN	Q13557	CAMK2D	T30320	T30327I	30327	Missense	distal	7	no	51.220	50.625	EPSD	ICGC	37.605	Down-regulation
CAMK_CAMK2_CAMK2D_ST	Q8WZ42	TTN	Q13557	CAMK2D	T30320	I30324K	30324	Missense	distal	4	no	51.220	51.717	EPSD	ICGC;COSMIC	37.605	Up-regulation
CAMK_CAMK2_CAMK2D_ST	Q8WZ42	TTN	Q13557	CAMK2D	T30320	R30317P	30317	Missense	distal	-3	no	51.220	-18.210	EPSD	ICGC;COSMIC	37.605	Loss
CAMK_CAMK2_CAMK2D_ST	Q8WZ42	TTN	Q13557	CAMK2D	T30384	A30387S	30387	Missense	distal	3	no	46.697	40.234	EPSD	ICGC;COSMIC	37.605	Down-regulation
CAMK_CAMK2_CAMK2D_ST	Q8WZ42	TTN	Q13557	CAMK2D	T30384	R30386M	30386	Missense	proximal	2	no	46.697	44.581	EPSD	ICGC;COSMIC	37.605	Down-regulation
CAMK_CAMK2_CAMK2D_ST	Q8WZ42	TTN	Q13557	CAMK2D	T30384	T30382N	30382	Missense	proximal	-2	no	46.697	47.780	EPSD	ICGC	37.605	Up-regulation
CAMK_CAMK2_CAMK2D_ST	Q8WZ42	TTN	Q13557	CAMK2D	T30384	A30387V	30387	Missense	distal	3	no	46.697	25.465	EPSD	ICGC;COSMIC	37.605	Loss
CAMK_CAMK2_CAMK2D_ST	Q8WZ42	TTN	Q13557	CAMK2D	T30384	A30387T	30387	Missense	distal	3	no	46.697	33.570	EPSD	ICGC;COSMIC	37.605	Loss
CAMK_CAMK2_CAMK2D_ST	Q8WZ42	TTN	Q13557	CAMK2D	T30456	V30459A	30459	Missense	distal	3	no	31.598	52.830	EPSD	ICGC;COSMIC	37.605	Gain
CAMK_CAMK2_CAMK2D_ST	Q8WZ42	TTN	Q13557	CAMK2D	T30516	R30509T	30509	Missense	distal	-7	no	39.000	36.141	EPSD	ICGC;COSMIC	37.605	Loss
CAMK_CAMK2_CAMK2D_ST	Q8WZ42	TTN	Q13557	CAMK2D	T30516	L30522H	30522	Missense	distal	6	no	39.000	40.964	EPSD	ICGC;COSMIC	37.605	Up-regulation
CAMK_CAMK2_CAMK2D_ST	Q8WZ42	TTN	Q13557	CAMK2D	T30669	D30666N	30666	Missense	distal	-3	no	22.167	39.151	EPSD	ICGC;COSMIC	37.605	Gain
CAMK_CAMK2_CAMK2D_ST	Q8WZ42	TTN	Q13557	CAMK2D	T30724	T30718N	30718	Missense	distal	-6	no	34.118	46.743	EPSD	ICGC;COSMIC	37.605	Gain
CAMK_CAMK2_CAMK2D_ST	Q8WZ42	TTN	Q13557	CAMK2D	S30812	R30815M	30815	Missense	distal	3	no	45.580	40.091	EPSD	ICGC;COSMIC	37.605	Down-regulation
CAMK_CAMK2_CAMK2D_ST	Q8WZ42	TTN	Q13557	CAMK2D	S30812	P30808H	30808	Missense	distal	-4	no	45.580	46.333	EPSD	ICGC;COSMIC	37.605	Up-regulation
CAMK_CAMK2_CAMK2D_ST	Q8WZ42	TTN	Q13557	CAMK2D	S30812	V30809I	30809	Missense	distal	-3	no	45.580	44.861	EPSD	ICGC;COSMIC	37.605	Down-regulation
CAMK_CAMK2_CAMK2D_ST	Q8WZ42	TTN	Q13557	CAMK2D	T31011	T31007N	31007	Missense	distal	-4	no	38.227	33.323	EPSD	ICGC;COSMIC	37.605	Loss
CAMK_CAMK2_CAMK2D_ST	Q8WZ42	TTN	Q13557	CAMK2D	T31011	R31017Q	31017	Missense	distal	6	no	38.227	40.778	EPSD	ICGC;COSMIC	37.605	Up-regulation
CAMK_CAMK2_CAMK2D_ST	Q8WZ42	TTN	Q13557	CAMK2D	T31020	L31024Q	31024	Missense	distal	4	no	37.935	37.668	EPSD	ICGC;COSMIC	37.605	Down-regulation
CAMK_CAMK2_CAMK2D_ST	Q8WZ42	TTN	Q13557	CAMK2D	T31020	R31017Q	31017	Missense	distal	-3	no	37.935	26.713	EPSD	ICGC;COSMIC	37.605	Loss
CAMK_CAMK2_CAMK2D_ST	Q8WZ42	TTN	Q13557	CAMK2D	T31022	L31024Q	31024	Missense	proximal	2	no	43.814	42.312	EPSD	ICGC;COSMIC	37.605	Down-regulation
CAMK_CAMK2_CAMK2D_ST	Q8WZ42	TTN	Q13557	CAMK2D	T31022	E31029K	31029	Missense	distal	7	no	43.814	43.893	EPSD	ICGC;COSMIC	37.605	Up-regulation
CAMK_CAMK2_CAMK2D_ST	Q8WZ42	TTN	Q13557	CAMK2D	T31022	R31017Q	31017	Missense	distal	-5	no	43.814	43.598	EPSD	ICGC;COSMIC	37.605	Down-regulation
CAMK_CAMK2_CAMK2D_ST	Q8WZ42	TTN	Q13557	CAMK2D	S31105	A31108T	31108	Missense	distal	3	no	43.194	30.066	EPSD	ICGC;COSMIC	37.605	Loss
CAMK_CAMK2_CAMK2D_ST	Q8WZ42	TTN	Q13557	CAMK2D	S31105	R31107S	31107	Missense	proximal	2	no	43.194	44.000	EPSD	ICGC	37.605	Up-regulation
CAMK_CAMK2_CAMK2D_ST	Q8WZ42	TTN	Q13557	CAMK2D	S31105	A31108D	31108	Missense	distal	3	no	43.194	27.193	EPSD	ICGC;COSMIC	37.605	Loss
CAMK_CAMK2_CAMK2D_ST	Q8WZ42	TTN	Q13557	CAMK2D	T31204	W31202R	31202	Missense	proximal	-2	no	47.250	48.435	EPSD	ICGC;COSMIC	37.605	Up-regulation
CAMK_CAMK2_CAMK2D_ST	Q8WZ42	TTN	Q13557	CAMK2D	T31204	D31206H	31206	Missense	proximal	2	no	47.250	35.676	EPSD	ICGC;COSMIC	37.605	Loss
CAMK_CAMK2_CAMK2D_ST	Q8WZ42	TTN	Q13557	CAMK2D	T31204	A31200D	31200	Missense	distal	-4	no	47.250	43.799	EPSD	ICGC;COSMIC	37.605	Down-regulation
CAMK_CAMK2_CAMK2D_ST	Q8WZ42	TTN	Q13557	CAMK2D	T31204	G31211S	31211	Missense	distal	7	no	47.250	46.322	EPSD	ICGC;COSMIC	37.605	Down-regulation
CAMK_CAMK2_CAMK2D_ST	Q8WZ42	TTN	Q13557	CAMK2D	T31204	R31210Q	31210	Missense	distal	6	no	47.250	49.800	EPSD	ICGC;COSMIC	37.605	Up-regulation
CAMK_CAMK2_CAMK2D_ST	Q8WZ42	TTN	Q13557	CAMK2D	T31204	D31206N	31206	Missense	proximal	2	no	47.250	35.824	EPSD	ICGC;COSMIC	37.605	Loss
CAMK_CAMK2_CAMK2D_ST	Q8WZ42	TTN	Q13557	CAMK2D	S31207	D31206N	31206	Missense	proximal	-1	no	36.211	38.197	EPSD	ICGC;COSMIC	37.605	Gain
CAMK_CAMK2_CAMK2D_ST	Q8WZ42	TTN	Q13557	CAMK2D	T31269	L31266I	31266	Missense	distal	-3	no	31.409	40.141	EPSD	ICGC	37.605	Gain
CAMK_CAMK2_CAMK2D_ST	Q8WZ42	TTN	Q13557	CAMK2D	T31313	N31307S	31307	Missense	distal	-6	no	41.906	32.253	EPSD	ICGC;COSMIC	37.605	Loss
CAMK_CAMK2_CAMK2D_ST	Q8WZ42	TTN	Q13557	CAMK2D	T31313	T31313N	31313	Missense	central	0	yes	41.906	0.000	EPSD	ICGC;COSMIC	37.605	Loss
CAMK_CAMK2_CAMK2D_ST	Q8WZ42	TTN	Q13557	CAMK2D	T31313	Y31316C	31316	Missense	distal	3	no	41.906	39.497	EPSD	ICGC;COSMIC	37.605	Down-regulation
CAMK_CAMK2_CAMK2D_ST	Q8WZ42	TTN	Q13557	CAMK2D	S31510	T31516A	31516	Missense	distal	6	no	34.566	38.159	EPSD	ICGC	37.605	Gain
CAMK_CAMK2_CAMK2D_ST	Q8WZ42	TTN	Q13557	CAMK2D	T31516	E31522K	31522	Missense	distal	6	no	45.061	45.608	EPSD	ICGC;COSMIC	37.605	Up-regulation
CAMK_CAMK2_CAMK2D_ST	Q8WZ42	TTN	Q13557	CAMK2D	T31516	R31513C	31513	Missense	distal	-3	no	45.061	15.558	EPSD	ICGC;COSMIC	37.605	Loss
CAMK_CAMK2_CAMK2D_ST	Q8WZ42	TTN	Q13557	CAMK2D	T31516	R31513H	31513	Missense	distal	-3	no	45.061	7.736	EPSD	ICGC;COSMIC;CCLE	37.605	Loss
CAMK_CAMK2_CAMK2D_ST	Q8WZ42	TTN	Q13557	CAMK2D	T31516	T31516A	31516	Missense	central	0	yes	45.061	0.000	EPSD	ICGC	37.605	Loss
CAMK_CAMK2_CAMK2D_ST	Q8WZ42	TTN	Q13557	CAMK2D	S31571	T31572I	31572	Missense	proximal	1	no	28.053	38.253	EPSD	ICGC	37.605	Gain
CAMK_CAMK2_CAMK2D_ST	Q8WZ42	TTN	Q13557	CAMK2D	S31571	A31568V	31568	Missense	distal	-3	no	28.053	41.626	EPSD	ICGC;COSMIC	37.605	Gain
CAMK_CAMK2_CAMK2D_ST	Q8WZ42	TTN	Q13557	CAMK2D	T31764	K31765N	31765	Missense	proximal	1	no	40.983	40.261	EPSD	ICGC	37.605	Down-regulation
CAMK_CAMK2_CAMK2D_ST	Q8WZ42	TTN	Q13557	CAMK2D	T31764	S31767F	31767	Missense	distal	3	no	40.983	35.160	EPSD	ICGC	37.605	Loss
CAMK_CAMK2_CAMK2D_ST	Q8WZ42	TTN	Q13557	CAMK2D	T31764	D31766G	31766	Missense	proximal	2	no	40.983	35.252	EPSD	ICGC;COSMIC	37.605	Loss
CAMK_CAMK2_CAMK2D_ST	Q8WZ42	TTN	Q13557	CAMK2D	T31764	A31771T	31771	Missense	distal	7	no	40.983	41.780	EPSD	ICGC;COSMIC	37.605	Up-regulation
CAMK_CAMK2_CAMK2D_ST	Q8WZ42	TTN	Q13557	CAMK2D	T31764	S31767Y	31767	Missense	distal	3	no	40.983	44.429	EPSD	ICGC;COSMIC	37.605	Up-regulation
CAMK_CAMK2_CAMK2D_ST	Q8WZ42	TTN	Q13557	CAMK2D	S31800	E31805K	31805	Missense	distal	5	no	39.180	39.631	EPSD	ICGC;COSMIC	37.605	Up-regulation
CAMK_CAMK2_CAMK2D_ST	Q8WZ42	TTN	Q13557	CAMK2D	S31800	T31803A	31803	Missense	distal	3	no	39.180	52.307	EPSD	ICGC;COSMIC	37.605	Up-regulation
CAMK_CAMK2_CAMK2D_ST	Q8WZ42	TTN	Q13557	CAMK2D	S31800	I31799M	31799	Missense	proximal	-1	no	39.180	37.578	EPSD	ICGC;COSMIC	37.605	Loss
CAMK_CAMK2_CAMK2D_ST	Q8WZ42	TTN	Q13557	CAMK2D	S31800	R31807P	31807	Missense	distal	7	no	39.180	39.990	EPSD	ICGC;COSMIC	37.605	Up-regulation
CAMK_CAMK2_CAMK2D_ST	Q8WZ42	TTN	Q13557	CAMK2D	S31800	S31800Y	31800	Missense	central	0	yes	39.180	0.000	EPSD	ICGC;COSMIC	37.605	Loss
CAMK_CAMK2_CAMK2D_ST	Q8WZ42	TTN	Q13557	CAMK2D	S31979	V31972A	31972	Missense	distal	-7	no	35.978	37.942	EPSD	ICGC;COSMIC	37.605	Gain
CAMK_CAMK2_CAMK2D_ST	Q8WZ42	TTN	Q13557	CAMK2D	S32008	R32007T	32007	Missense	proximal	-1	no	46.188	45.194	EPSD	ICGC;COSMIC	37.605	Down-regulation
CAMK_CAMK2_CAMK2D_ST	Q8WZ42	TTN	Q13557	CAMK2D	S32008	I32004T	32004	Missense	distal	-4	no	46.188	47.542	EPSD	ICGC;COSMIC	37.605	Up-regulation
CAMK_CAMK2_CAMK2D_ST	Q8WZ42	TTN	Q13557	CAMK2D	S32133	S32130R	32130	Missense	distal	-3	no	34.449	50.623	EPSD	ICGC;COSMIC	37.605	Gain
CAMK_CAMK2_CAMK2D_ST	Q8WZ42	TTN	Q13557	CAMK2D	S32133	P32135L	32135	Missense	proximal	2	no	34.449	38.318	EPSD	ICGC;COSMIC	37.605	Gain
CAMK_CAMK2_CAMK2D_ST	Q8WZ42	TTN	Q13557	CAMK2D	S32162	V32161F	32161	Missense	proximal	-1	no	54.358	51.324	EPSD	ICGC;COSMIC	37.605	Down-regulation
CAMK_CAMK2_CAMK2D_ST	Q8WZ42	TTN	Q13557	CAMK2D	S32162	E32157K	32157	Missense	distal	-5	no	54.358	53.182	EPSD	ICGC;COSMIC	37.605	Down-regulation
CAMK_CAMK2_CAMK2D_ST	Q8WZ42	TTN	Q13557	CAMK2D	S32312	T32308S	32308	Missense	distal	-4	no	46.730	44.705	EPSD	ICGC;COSMIC	37.605	Down-regulation
CAMK_CAMK2_CAMK2D_ST	Q8WZ42	TTN	Q13557	CAMK2D	T32609	R32605C	32605	Missense	distal	-4	no	45.684	43.562	EPSD	ICGC;COSMIC	37.605	Down-regulation
CAMK_CAMK2_CAMK2D_ST	Q8WZ42	TTN	Q13557	CAMK2D	T32609	R32605H	32605	Missense	distal	-4	no	45.684	44.750	EPSD	ICGC;COSMIC	37.605	Down-regulation
CAMK_CAMK2_CAMK2D_ST	Q8WZ42	TTN	Q13557	CAMK2D	T32609	R32606K	32606	Missense	distal	-3	no	45.684	34.276	EPSD	ICGC;COSMIC	37.605	Loss
CAMK_CAMK2_CAMK2D_ST	Q8WZ42	TTN	Q13557	CAMK2D	T32609	L32612I	32612	Missense	distal	3	no	45.684	46.038	EPSD	ICGC	37.605	Up-regulation
CAMK_CAMK2_CAMK2D_ST	Q8WZ42	TTN	Q13557	CAMK2D	T32609	E32614K	32614	Missense	distal	5	no	45.684	46.135	EPSD	ICGC	37.605	Up-regulation
CAMK_CAMK2_CAMK2D_ST	Q8WZ42	TTN	Q13557	CAMK2D	T32609	D32608N	32608	Missense	proximal	-1	no	45.684	47.670	EPSD	ICGC;COSMIC	37.605	Up-regulation
CAMK_CAMK2_CAMK2D_ST	Q8WZ42	TTN	Q13557	CAMK2D	T32609	R32606I	32606	Missense	distal	-3	no	45.684	32.581	EPSD	ICGC;COSMIC	37.605	Loss
CAMK_CAMK2_CAMK2D_ST	Q8WZ42	TTN	Q13557	CAMK2D	T32609	K32602N	32602	Missense	distal	-7	no	45.684	38.898	EPSD	ICGC;COSMIC	37.605	Down-regulation
CAMK_CAMK2_CAMK2D_ST	Q8WZ42	TTN	Q13557	CAMK2D	T32667	N32662I	32662	Missense	distal	-5	no	38.079	36.657	EPSD	ICGC;COSMIC	37.605	Loss
CAMK_CAMK2_CAMK2D_ST	Q8WZ42	TTN	Q13557	CAMK2D	T32798	T32800A	32800	Missense	proximal	2	no	33.415	38.066	EPSD	ICGC;COSMIC	37.605	Gain
CAMK_CAMK2_CAMK2D_ST	Q8WZ42	TTN	Q13557	CAMK2D	S32847	E32844K	32844	Missense	distal	-3	no	22.345	56.628	EPSD	ICGC	37.605	Gain
CAMK_CAMK2_CAMK2D_ST	Q8WZ42	TTN	Q13557	CAMK2D	T32911	R32905H	32905	Missense	distal	-6	no	48.992	46.817	EPSD	ICGC;COSMIC	37.605	Down-regulation
CAMK_CAMK2_CAMK2D_ST	Q8WZ42	TTN	Q13557	CAMK2D	T32911	K32906T	32906	Missense	distal	-5	no	48.992	50.407	EPSD	ICGC	37.605	Up-regulation
CAMK_CAMK2_CAMK2D_ST	Q8WZ42	TTN	Q13557	CAMK2D	T32911	P32904S	32904	Missense	distal	-7	no	48.992	52.243	EPSD	ICGC	37.605	Up-regulation
CAMK_CAMK2_CAMK2D_ST	Q8WZ42	TTN	Q13557	CAMK2D	T32911	R32917C	32917	Missense	distal	6	no	48.992	48.315	EPSD	ICGC;COSMIC	37.605	Down-regulation
CAMK_CAMK2_CAMK2D_ST	Q8WZ42	TTN	Q13557	CAMK2D	T32911	Q32909R	32909	Missense	proximal	-2	no	48.992	49.510	EPSD	ICGC;COSMIC	37.605	Up-regulation
CAMK_CAMK2_CAMK2D_ST	Q8WZ42	TTN	Q13557	CAMK2D	T32998	D33002N	33002	Missense	distal	4	no	46.829	48.454	EPSD	ICGC;COSMIC	37.605	Up-regulation
CAMK_CAMK2_CAMK2D_ST	Q8WZ42	TTN	Q13557	CAMK2D	T32998	R32995H	32995	Missense	distal	-3	no	46.829	9.505	EPSD	ICGC;COSMIC	37.605	Loss
CAMK_CAMK2_CAMK2D_ST	Q8WZ42	TTN	Q13557	CAMK2D	T32998	Y33003H	33003	Missense	distal	5	no	46.829	47.807	EPSD	ICGC;COSMIC	37.605	Up-regulation
CAMK_CAMK2_CAMK2D_ST	Q8WZ42	TTN	Q13557	CAMK2D	T32998	R32995S	32995	Missense	distal	-3	no	46.829	30.655	EPSD	ICGC	37.605	Loss
CAMK_CAMK2_CAMK2D_ST	Q8WZ42	TTN	Q13557	CAMK2D	T32998	D33004E	33004	Missense	distal	6	no	46.829	47.480	EPSD	ICGC	37.605	Up-regulation
CAMK_CAMK2_CAMK2D_ST	Q8WZ42	TTN	Q13557	CAMK2D	T32998	D33002G	33002	Missense	distal	4	no	46.829	48.148	EPSD	ICGC;COSMIC	37.605	Up-regulation
CAMK_CAMK2_CAMK2D_ST	Q8WZ42	TTN	Q13557	CAMK2D	T32998	P33001S	33001	Missense	distal	3	no	46.829	48.101	EPSD	ICGC;COSMIC	37.605	Up-regulation
CAMK_CAMK2_CAMK2D_ST	Q8WZ42	TTN	Q13557	CAMK2D	T32998	R32996Q	32996	Missense	proximal	-2	no	46.829	46.311	EPSD	ICGC;COSMIC	37.605	Down-regulation
CAMK_CAMK2_CAMK2D_ST	Q8WZ42	TTN	Q13557	CAMK2D	T32998	R32997H	32997	Missense	proximal	-1	no	46.829	42.351	EPSD	ICGC;COSMIC	37.605	Down-regulation
CAMK_CAMK2_CAMK2D_ST	Q8WZ42	TTN	Q13557	CAMK2D	T32998	R32995C	32995	Missense	distal	-3	no	46.829	17.327	EPSD	ICGC	37.605	Loss
CAMK_CAMK2_CAMK2D_ST	Q8WZ42	TTN	Q13557	CAMK2D	S33071	P33072Q	33072	Missense	proximal	1	no	46.247	50.945	EPSD	ICGC;COSMIC	37.605	Up-regulation
CAMK_CAMK2_CAMK2D_ST	Q8WZ42	TTN	Q13557	CAMK2D	S33071	V33078M	33078	Missense	distal	7	no	46.247	46.321	EPSD	ICGC;COSMIC	37.605	Up-regulation
CAMK_CAMK2_CAMK2D_ST	Q8WZ42	TTN	Q13557	CAMK2D	S33071	R33068C	33068	Missense	distal	-3	no	46.247	16.745	EPSD	ICGC;COSMIC	37.605	Loss
CAMK_CAMK2_CAMK2D_ST	Q8WZ42	TTN	Q13557	CAMK2D	S33203	R33198Q	33198	Missense	distal	-5	no	48.714	48.498	EPSD	ICGC;COSMIC	37.605	Down-regulation
CAMK_CAMK2_CAMK2D_ST	Q8WZ42	TTN	Q13557	CAMK2D	S33203	M33210I	33210	Missense	distal	7	no	48.714	48.897	EPSD	ICGC;COSMIC	37.605	Up-regulation
CAMK_CAMK2_CAMK2D_ST	Q8WZ42	TTN	Q13557	CAMK2D	S33203	R33200H	33200	Missense	distal	-3	no	48.714	11.389	EPSD	ICGC;COSMIC	37.605	Loss
CAMK_CAMK2_CAMK2D_ST	Q8WZ42	TTN	Q13557	CAMK2D	T33231	E33228K	33228	Missense	distal	-3	no	7.770	42.053	EPSD	ICGC;COSMIC	37.605	Gain
CAMK_CAMK2_CAMK2D_ST	Q8WZ42	TTN	Q13557	CAMK2D	T33241	P33238S	33238	Missense	distal	-3	no	-9.057	44.198	EPSD	ICGC;COSMIC	37.605	Gain
CAMK_CAMK2_CAMK2D_ST	Q8WZ42	TTN	Q13557	CAMK2D	S33245	R33242H	33242	Missense	distal	-3	no	45.143	7.818	EPSD	ICGC;COSMIC	37.605	Loss
CAMK_CAMK2_CAMK2D_ST	Q8WZ42	TTN	Q13557	CAMK2D	S33245	R33244Q	33244	Missense	proximal	-1	no	45.143	42.239	EPSD	ICGC;COSMIC	37.605	Down-regulation
CAMK_CAMK2_CAMK2D_ST	Q8WZ42	TTN	Q13557	CAMK2D	S33245	P33238S	33238	Missense	distal	-7	no	45.143	48.394	EPSD	ICGC;COSMIC	37.605	Up-regulation
CAMK_CAMK2_CAMK2D_ST	Q8WZ42	TTN	Q13557	CAMK2D	S33245	P33243Q	33243	Missense	proximal	-2	no	45.143	45.059	EPSD	ICGC;COSMIC	37.605	Down-regulation
CAMK_CAMK2_CAMK2D_ST	Q8WZ42	TTN	Q13557	CAMK2D	S33247	S33254L	33254	Missense	distal	7	no	43.037	44.922	EPSD	ICGC;COSMIC	37.605	Up-regulation
CAMK_CAMK2_CAMK2D_ST	Q8WZ42	TTN	Q13557	CAMK2D	S33247	R33242H	33242	Missense	distal	-5	no	43.037	44.942	EPSD	ICGC;COSMIC	37.605	Up-regulation
CAMK_CAMK2_CAMK2D_ST	Q8WZ42	TTN	Q13557	CAMK2D	S33247	R33253K	33253	Missense	distal	6	no	43.037	42.384	EPSD	ICGC	37.605	Down-regulation
CAMK_CAMK2_CAMK2D_ST	Q8WZ42	TTN	Q13557	CAMK2D	S33247	R33244Q	33244	Missense	distal	-3	no	43.037	31.815	EPSD	ICGC;COSMIC	37.605	Loss
CAMK_CAMK2_CAMK2D_ST	Q8WZ42	TTN	Q13557	CAMK2D	S33247	P33243Q	33243	Missense	distal	-4	no	43.037	41.727	EPSD	ICGC;COSMIC	37.605	Down-regulation
CAMK_CAMK2_CAMK2D_ST	Q8WZ42	TTN	Q13557	CAMK2D	S33254	S33254L	33254	Missense	central	0	yes	49.818	0.000	EPSD	ICGC;COSMIC	37.605	Loss
CAMK_CAMK2_CAMK2D_ST	Q8WZ42	TTN	Q13557	CAMK2D	S33254	R33253K	33253	Missense	proximal	-1	no	49.818	48.402	EPSD	ICGC	37.605	Down-regulation
CAMK_CAMK2_CAMK2D_ST	Q8WZ42	TTN	Q13557	CAMK2D	S33256	R33263T	33263	Missense	distal	7	no	37.559	39.498	EPSD	ICGC;COSMIC	37.605	Gain
CAMK_CAMK2_CAMK2D_ST	Q8WZ42	TTN	Q13557	CAMK2D	S33256	R33263I	33263	Missense	distal	7	no	37.559	38.903	EPSD	ICGC	37.605	Gain
CAMK_CAMK2_CAMK2D_ST	Q8WZ42	TTN	Q13557	CAMK2D	S33451	T33448K	33448	Missense	distal	-3	no	31.840	42.064	EPSD	ICGC	37.605	Gain
CAMK_CAMK2_CAMK2D_ST	Q8WZ42	TTN	Q13557	CAMK2D	T33484	A33487V	33487	Missense	distal	3	no	38.462	17.230	EPSD	ICGC;COSMIC	37.605	Loss
CAMK_CAMK2_CAMK2D_ST	Q8WZ42	TTN	Q13557	CAMK2D	T33484	T33479N	33479	Missense	distal	-5	no	38.462	38.725	EPSD	ICGC	37.605	Up-regulation
CAMK_CAMK2_CAMK2D_ST	Q8WZ42	TTN	Q13557	CAMK2D	T33484	T33484A	33484	Missense	central	0	yes	38.462	0.000	EPSD	ICGC;COSMIC	37.605	Loss
CAMK_CAMK2_CAMK2D_ST	Q8WZ42	TTN	Q13557	CAMK2D	T33484	L33491I	33491	Missense	distal	7	no	38.462	38.079	EPSD	ICGC;COSMIC	37.605	Down-regulation
CAMK_CAMK2_CAMK2D_ST	Q8WZ42	TTN	Q13557	CAMK2D	T33485	A33487V	33487	Missense	proximal	2	no	47.096	41.221	EPSD	ICGC;COSMIC	37.605	Down-regulation
CAMK_CAMK2_CAMK2D_ST	Q8WZ42	TTN	Q13557	CAMK2D	T33485	T33479N	33479	Missense	distal	-6	no	47.096	59.720	EPSD	ICGC	37.605	Up-regulation
CAMK_CAMK2_CAMK2D_ST	Q8WZ42	TTN	Q13557	CAMK2D	T33485	T33484A	33484	Missense	proximal	-1	no	47.096	45.441	EPSD	ICGC;COSMIC	37.605	Down-regulation
CAMK_CAMK2_CAMK2D_ST	Q8WZ42	TTN	Q13557	CAMK2D	T33485	L33491I	33491	Missense	distal	6	no	47.096	46.982	EPSD	ICGC;COSMIC	37.605	Down-regulation
CAMK_CAMK2_CAMK2D_ST	Q8WZ42	TTN	Q13557	CAMK2D	T33498	R33495W	33495	Missense	distal	-3	no	47.077	6.040	EPSD	ICGC;COSMIC	37.605	Loss
CAMK_CAMK2_CAMK2D_ST	Q8WZ42	TTN	Q13557	CAMK2D	T33498	E33503K	33503	Missense	distal	5	no	47.077	47.528	EPSD	ICGC;COSMIC	37.605	Up-regulation
CAMK_CAMK2_CAMK2D_ST	Q8WZ42	TTN	Q13557	CAMK2D	T33498	A33505E	33505	Missense	distal	7	no	47.077	47.345	EPSD	ICGC	37.605	Up-regulation
CAMK_CAMK2_CAMK2D_ST	Q8WZ42	TTN	Q13557	CAMK2D	T33498	S33496F	33496	Missense	proximal	-2	no	47.077	46.834	EPSD	ICGC;COSMIC	37.605	Down-regulation
CAMK_CAMK2_CAMK2D_ST	Q8WZ42	TTN	Q13557	CAMK2D	T33498	L33491I	33491	Missense	distal	-7	no	47.077	46.503	EPSD	ICGC;COSMIC	37.605	Down-regulation
CAMK_CAMK2_CAMK2D_ST	Q8WZ42	TTN	Q13557	CAMK2D	T33498	R33495Q	33495	Missense	distal	-3	no	47.077	35.854	EPSD	ICGC;COSMIC	37.605	Loss
CAMK_CAMK2_CAMK2D_ST	Q8WZ42	TTN	Q13557	CAMK2D	S33529	R33533H	33533	Missense	distal	4	no	41.362	39.789	EPSD	ICGC;COSMIC	37.605	Down-regulation
CAMK_CAMK2_CAMK2D_ST	Q8WZ42	TTN	Q13557	CAMK2D	S33529	L33522M	33522	Missense	distal	-7	no	41.362	40.435	EPSD	ICGC	37.605	Down-regulation
CAMK_CAMK2_CAMK2D_ST	Q8WZ42	TTN	Q13557	CAMK2D	S33529	R33533C	33533	Missense	distal	4	no	41.362	42.578	EPSD	ICGC	37.605	Up-regulation
CAMK_CAMK2_CAMK2D_ST	Q8WZ42	TTN	Q13557	CAMK2D	S33595	P33591Q	33591	Missense	distal	-4	no	52.125	50.814	EPSD	ICGC;COSMIC	37.605	Down-regulation
CAMK_CAMK2_CAMK2D_ST	Q8WZ42	TTN	Q13557	CAMK2D	S33595	P33598T	33598	Missense	distal	3	no	52.125	46.732	EPSD	ICGC;COSMIC	37.605	Down-regulation
CAMK_CAMK2_CAMK2D_ST	Q8WZ42	TTN	Q13557	CAMK2D	S33595	P33590S	33590	Missense	distal	-5	no	52.125	51.503	EPSD	ICGC	37.605	Down-regulation
CAMK_CAMK2_CAMK2D_ST	Q8WZ42	TTN	Q13557	CAMK2D	S33595	P33590L	33590	Missense	distal	-5	no	52.125	50.764	EPSD	ICGC;COSMIC	37.605	Down-regulation
CAMK_CAMK2_CAMK2D_ST	Q8WZ42	TTN	Q13557	CAMK2D	S33595	S33595F	33595	Missense	central	0	yes	52.125	0.000	EPSD	ICGC;COSMIC	37.605	Loss
CAMK_CAMK2_CAMK2D_ST	Q8WZ42	TTN	Q13557	CAMK2D	S33595	R33592I	33592	Missense	distal	-3	no	52.125	39.021	EPSD	ICGC;COSMIC	37.605	Down-regulation
CAMK_CAMK2_CAMK2D_ST	Q8WZ42	TTN	Q13557	CAMK2D	S33602	S33608F	33608	Missense	distal	6	no	56.021	55.219	EPSD	ICGC;COSMIC	37.605	Down-regulation
CAMK_CAMK2_CAMK2D_ST	Q8WZ42	TTN	Q13557	CAMK2D	S33602	P33598T	33598	Missense	distal	-4	no	56.021	57.487	EPSD	ICGC;COSMIC	37.605	Up-regulation
CAMK_CAMK2_CAMK2D_ST	Q8WZ42	TTN	Q13557	CAMK2D	S33602	S33608C	33608	Missense	distal	6	no	56.021	56.385	EPSD	ICGC;COSMIC	37.605	Up-regulation
CAMK_CAMK2_CAMK2D_ST	Q8WZ42	TTN	Q13557	CAMK2D	S33602	S33608Y	33608	Missense	distal	6	no	56.021	55.689	EPSD	ICGC	37.605	Down-regulation
CAMK_CAMK2_CAMK2D_ST	Q8WZ42	TTN	Q13557	CAMK2D	S33602	S33595F	33595	Missense	distal	-7	no	56.021	53.357	EPSD	ICGC;COSMIC	37.605	Down-regulation
CAMK_CAMK2_CAMK2D_ST	Q8WZ42	TTN	Q13557	CAMK2D	S33614	R33611Q	33611	Missense	distal	-3	no	46.937	35.715	EPSD	ICGC;COSMIC	37.605	Loss
CAMK_CAMK2_CAMK2D_ST	Q8WZ42	TTN	Q13557	CAMK2D	S33614	P33620L	33620	Missense	distal	6	no	46.937	40.594	EPSD	ICGC	37.605	Down-regulation
CAMK_CAMK2_CAMK2D_ST	Q8WZ42	TTN	Q13557	CAMK2D	S33614	S33608F	33608	Missense	distal	-6	no	46.937	46.397	EPSD	ICGC;COSMIC	37.605	Down-regulation
CAMK_CAMK2_CAMK2D_ST	Q8WZ42	TTN	Q13557	CAMK2D	S33614	P33617H	33617	Missense	distal	3	no	46.937	37.006	EPSD	ICGC	37.605	Loss
CAMK_CAMK2_CAMK2D_ST	Q8WZ42	TTN	Q13557	CAMK2D	S33614	S33608C	33608	Missense	distal	-6	no	46.937	47.164	EPSD	ICGC;COSMIC	37.605	Up-regulation
CAMK_CAMK2_CAMK2D_ST	Q8WZ42	TTN	Q13557	CAMK2D	S33614	S33608Y	33608	Missense	distal	-6	no	46.937	43.618	EPSD	ICGC	37.605	Down-regulation
CAMK_CAMK2_CAMK2D_ST	Q8WZ42	TTN	Q13557	CAMK2D	T33626	P33620L	33620	Missense	distal	-6	no	49.680	42.730	EPSD	ICGC	37.605	Down-regulation
CAMK_CAMK2_CAMK2D_ST	Q8WZ42	TTN	Q13557	CAMK2D	T33626	T33626K	33626	Missense	central	0	yes	49.680	0.000	EPSD	ICGC	37.605	Loss
CAMK_CAMK2_CAMK2D_ST	Q8WZ42	TTN	Q13557	CAMK2D	T33626	T33633K	33633	Missense	distal	7	no	49.680	49.230	EPSD	ICGC	37.605	Down-regulation
CAMK_CAMK2_CAMK2D_ST	Q8WZ42	TTN	Q13557	CAMK2D	T33626	T33631K	33631	Missense	distal	5	no	49.680	48.547	EPSD	ICGC	37.605	Down-regulation
CAMK_CAMK2_CAMK2D_ST	Q8WZ42	TTN	Q13557	CAMK2D	T33626	E33627K	33627	Missense	proximal	1	no	49.680	50.154	EPSD	ICGC;COSMIC	37.605	Up-regulation
CAMK_CAMK2_CAMK2D_ST	Q8WZ42	TTN	Q13557	CAMK2D	T33843	Y33849H	33849	Missense	distal	6	no	40.687	42.541	EPSD	ICGC	37.605	Up-regulation
CAMK_CAMK2_CAMK2D_ST	Q8WZ42	TTN	Q13557	CAMK2D	T33843	L33848R	33848	Missense	distal	5	no	40.687	41.996	EPSD	ICGC;COSMIC	37.605	Up-regulation
CAMK_CAMK2_CAMK2D_ST	Q8WZ42	TTN	Q13557	CAMK2D	T33843	S33844Y	33844	Missense	proximal	1	no	40.687	37.106	EPSD	ICGC	37.605	Loss
CAMK_CAMK2_CAMK2D_ST	Q8WZ42	TTN	Q13557	CAMK2D	S34108	S34105L	34105	Missense	distal	-3	no	43.454	37.792	EPSD	ICGC;COSMIC	37.605	Down-regulation
CAMK_CAMK2_CAMK2D_ST	Q8WZ42	TTN	Q13557	CAMK2D	S34108	R34113K	34113	Missense	distal	5	no	43.454	43.009	EPSD	ICGC	37.605	Down-regulation
CAMK_CAMK2_CAMK2D_ST	Q8WZ42	TTN	Q13557	CAMK2D	S34108	S34104Y	34104	Missense	distal	-4	no	43.454	46.009	EPSD	ICGC;COSMIC	37.605	Up-regulation
CAMK_CAMK2_CAMK2D_ST	Q8WZ42	TTN	Q13557	CAMK2D	S34108	R34111H	34111	Missense	distal	3	no	43.454	33.907	EPSD	ICGC;COSMIC	37.605	Loss
CAMK_CAMK2_CAMK2D_ST	Q8WZ42	TTN	Q13557	CAMK2D	S34108	R34111C	34111	Missense	distal	3	no	43.454	46.146	EPSD	ICGC;COSMIC	37.605	Up-regulation
CAMK_CAMK2_CAMK2D_ST	Q8WZ42	TTN	Q13557	CAMK2D	S34108	S34102Y	34102	Missense	distal	-6	no	43.454	40.134	EPSD	ICGC;COSMIC;CCLE	37.605	Down-regulation
CAMK_CAMK2_CAMK2D_ST	Q8WZ42	TTN	Q13557	CAMK2D	S34108	V34115A	34115	Missense	distal	7	no	43.454	43.509	EPSD	ICGC	37.605	Up-regulation
CAMK_CAMK2_CAMK2D_ST	Q8WZ42	TTN	Q13557	CAMK2D	S34108	S34104T	34104	Missense	distal	-4	no	43.454	45.480	EPSD	ICGC	37.605	Up-regulation
CAMK_CAMK2_CAMK2D_ST	Q8WZ42	TTN	Q13557	CAMK2D	S34108	S34104A	34104	Missense	distal	-4	no	43.454	45.064	EPSD	ICGC;COSMIC	37.605	Up-regulation
CAMK_CAMK2_CAMK2D_ST	Q8WZ42	TTN	Q13557	CAMK2D	S34266	L34261V	34261	Missense	distal	-5	no	52.585	54.067	EPSD	ICGC;COSMIC	37.605	Up-regulation
CAMK_CAMK2_CAMK2D_ST	Q8WZ42	TTN	Q13557	CAMK2D	S34266	D34264N	34264	Missense	proximal	-2	no	52.585	53.293	EPSD	ICGC;COSMIC	37.605	Up-regulation
CAMK_CAMK2_CAMK2D_ST	Q8WZ42	TTN	Q13557	CAMK2D	S34266	S34263F	34263	Missense	distal	-3	no	52.585	53.772	EPSD	ICGC;COSMIC	37.605	Up-regulation
CAMK_CAMK2_CAMK2D_ST	Q8WZ42	TTN	Q13557	CAMK2D	S34266	D34268V	34268	Missense	proximal	2	no	52.585	40.279	EPSD	ICGC;COSMIC	37.605	Down-regulation
CAMK_CAMK2_CAMK2D_ST	Q8WZ42	TTN	Q13557	CAMK2D	S34266	D34268N	34268	Missense	proximal	2	no	52.585	41.160	EPSD	ICGC	37.605	Down-regulation
CAMK_CAMK2_CAMK2D_ST	Q14524	SCN5A	Q13557	CAMK2D	S12	G9V	9	Missense	distal	-3	no	16.465	47.039	EPSD	ICGC;COSMIC	37.605	Gain
CAMK_CAMK2_CAMK2D_ST	Q14524	SCN5A	Q13557	CAMK2D	T17	T10N	10	Missense	distal	-7	no	50.514	48.176	EPSD	ICGC;COSMIC	37.605	Down-regulation
CAMK_CAMK2_CAMK2D_ST	Q14524	SCN5A	Q13557	CAMK2D	T17	R18W	18	Missense	proximal	1	no	50.514	44.997	EPSD	ICGC;COSMIC	37.605	Down-regulation
CAMK_CAMK2_CAMK2D_ST	Q14524	SCN5A	Q13557	CAMK2D	T37	K31Q	31	Missense	distal	-6	no	45.792	51.065	EPSD	ICGC;COSMIC	37.605	Up-regulation
CAMK_CAMK2_CAMK2D_ST	Q14524	SCN5A	Q13557	CAMK2D	T37	E30K	30	Missense	distal	-7	no	45.792	52.059	EPSD	ICGC;COSMIC	37.605	Up-regulation
CAMK_CAMK2_CAMK2D_ST	Q14524	SCN5A	Q13557	CAMK2D	S231	K228N	228	Missense	distal	-3	no	40.944	32.652	EPSD	ICGC;COSMIC	37.605	Loss
CAMK_CAMK2_CAMK2D_ST	Q14524	SCN5A	Q13557	CAMK2D	S231	I233T	233	Missense	proximal	2	no	40.944	36.851	EPSD	ICGC	37.605	Loss
CAMK_CAMK2_CAMK2D_ST	Q14524	SCN5A	Q13557	CAMK2D	S231	T229I	229	Missense	proximal	-2	no	40.944	41.922	EPSD	ICGC	37.605	Up-regulation
CAMK_CAMK2_CAMK2D_ST	Q14524	SCN5A	Q13557	CAMK2D	S231	S234L	234	Missense	distal	3	no	40.944	31.053	EPSD	ICGC;COSMIC	37.605	Loss
CAMK_CAMK2_CAMK2D_ST	Q14524	SCN5A	Q13557	CAMK2D	S231	A226T	226	Missense	distal	-5	no	40.944	39.859	EPSD	ICGC;COSMIC	37.605	Down-regulation
CAMK_CAMK2_CAMK2D_ST	Q14524	SCN5A	Q13557	CAMK2D	S231	R225Q	225	Missense	distal	-6	no	40.944	43.806	EPSD	ICGC;COSMIC	37.605	Up-regulation
CAMK_CAMK2_CAMK2D_ST	Q14524	SCN5A	Q13557	CAMK2D	S231	R225W	225	Missense	distal	-6	no	40.944	32.597	EPSD	ICGC;COSMIC;GDSC;CCLE	37.605	Loss
CAMK_CAMK2_CAMK2D_ST	Q14524	SCN5A	Q13557	CAMK2D	S231	K228T	228	Missense	distal	-3	no	40.944	30.720	EPSD	ICGC;COSMIC	37.605	Loss
CAMK_CAMK2_CAMK2D_ST	Q14524	SCN5A	Q13557	CAMK2D	S484	G490E	490	Missense	distal	6	no	45.288	43.616	EPSD	ICGC	37.605	Down-regulation
CAMK_CAMK2_CAMK2D_ST	Q14524	SCN5A	Q13557	CAMK2D	S484	R481W	481	Missense	distal	-3	no	45.288	4.252	EPSD	ICGC;COSMIC	37.605	Loss
CAMK_CAMK2_CAMK2D_ST	Q14524	SCN5A	Q13557	CAMK2D	S484	S484P	484	Missense	central	0	yes	45.288	0.000	EPSD	ICGC	37.605	Loss
CAMK_CAMK2_CAMK2D_ST	Q14524	SCN5A	Q13557	CAMK2D	S484	R481L	481	Missense	distal	-3	no	45.288	23.453	EPSD	ICGC;COSMIC	37.605	Loss
CAMK_CAMK2_CAMK2D_ST	Q14524	SCN5A	Q13557	CAMK2D	S484	G490V	490	Missense	distal	6	no	45.288	44.970	EPSD	ICGC;COSMIC	37.605	Down-regulation
CAMK_CAMK2_CAMK2D_ST	Q14524	SCN5A	Q13557	CAMK2D	S497	K496R	496	Missense	proximal	-1	no	36.751	38.167	EPSD	ICGC	37.605	Gain
CAMK_CAMK2_CAMK2D_ST	Q14524	SCN5A	Q13557	CAMK2D	S516	S510N	510	Missense	distal	-6	no	71.045	80.698	PhosphoSitePlus;EPSD	ICGC	37.605	Up-regulation
CAMK_CAMK2_CAMK2D_ST	Q14524	SCN5A	Q13557	CAMK2D	S516	S510G	510	Missense	distal	-6	no	71.045	72.325	PhosphoSitePlus;EPSD	ICGC;COSMIC	37.605	Up-regulation
CAMK_CAMK2_CAMK2D_ST	Q14524	SCN5A	Q13557	CAMK2D	T594	G599E	599	Missense	distal	5	no	79.320	77.892	EPSD;PhosphoSitePlus	ICGC	37.605	Down-regulation
CAMK_CAMK2_CAMK2D_ST	Q14524	SCN5A	Q13557	CAMK2D	S667	V668I	668	Missense	proximal	1	no	36.570	42.293	EPSD	ICGC;COSMIC	37.605	Gain
CAMK_CAMK2_CAMK2D_ST	Q14524	SCN5A	Q13557	CAMK2D	S667	S664R	664	Missense	distal	-3	no	36.570	52.744	EPSD	ICGC	37.605	Gain
CAMK_CAMK2_CAMK2D_ST	Q14524	SCN5A	Q13557	CAMK2D	T670	S664R	664	Missense	distal	-6	no	36.382	39.480	EPSD	ICGC	37.605	Gain
CAMK_CAMK2_CAMK2D_ST	Q14524	SCN5A	Q13557	CAMK2D	S671	V668I	668	Missense	distal	-3	no	45.789	45.070	EPSD	ICGC;COSMIC	37.605	Down-regulation
CAMK_CAMK2_CAMK2D_ST	Q14524	SCN5A	Q13557	CAMK2D	S671	E675D	675	Missense	distal	4	no	45.789	44.204	EPSD	ICGC;COSMIC	37.605	Down-regulation
CAMK_CAMK2_CAMK2D_ST	Q14524	SCN5A	Q13557	CAMK2D	S671	S664R	664	Missense	distal	-7	no	45.789	47.848	EPSD	ICGC	37.605	Up-regulation
CAMK_CAMK2_CAMK2D_ST	Q14524	SCN5A	Q13557	CAMK2D	S805	R811H	811	Missense	distal	6	no	38.187	38.669	EPSD	ICGC;COSMIC	37.605	Up-regulation
CAMK_CAMK2_CAMK2D_ST	Q14524	SCN5A	Q13557	CAMK2D	S1003	S1010F	1010	Missense	distal	7	no	42.601	43.250	EPSD	ICGC	37.605	Up-regulation
CAMK_CAMK2_CAMK2D_ST	Q14524	SCN5A	Q13557	CAMK2D	S1083	P1089L	1089	Missense	distal	6	no	51.699	45.356	EPSD	ICGC;COSMIC	37.605	Down-regulation
CAMK_CAMK2_CAMK2D_ST	Q14524	SCN5A	Q13557	CAMK2D	S1083	G1084V	1084	Missense	proximal	1	no	51.699	52.302	EPSD	ICGC;COSMIC	37.605	Up-regulation
CAMK_CAMK2_CAMK2D_ST	Q14524	SCN5A	Q13557	CAMK2D	S1083	G1084D	1084	Missense	proximal	1	no	51.699	46.774	EPSD	ICGC;COSMIC	37.605	Down-regulation
CAMK_CAMK2_CAMK2D_ST	Q14524	SCN5A	Q13557	CAMK2D	S1985	D1978N	1978	Missense	distal	-7	no	38.885	38.683	EPSD	ICGC;COSMIC	37.605	Down-regulation
CAMK_CAMK2_CAMK2D_ST	Q14654	KCNJ11	Q13557	CAMK2D	T224	E229K	229	Missense	distal	5	no	73.333	73.784	PhosphoSitePlus	ICGC	37.605	Up-regulation
CAMK_CAMK2_CAMK2D_ST	Q14654	KCNJ11	Q13557	CAMK2D	T224	E227K	227	Missense	distal	3	no	73.333	67.314	PhosphoSitePlus	ICGC;COSMIC	37.605	Down-regulation
CAMK_CAMK2_CAMK2D_ST	Q14654	KCNJ11	Q13557	CAMK2D	T224	R221C	221	Missense	distal	-3	no	73.333	43.831	PhosphoSitePlus	ICGC;COSMIC	37.605	Down-regulation
CAMK_CAMK2_CAMK2D_ST	Q14654	KCNJ11	Q13557	CAMK2D	T224	R221H	221	Missense	distal	-3	no	73.333	36.009	PhosphoSitePlus	ICGC;COSMIC	37.605	Loss
CAMK_CAMK2_CAMK2D_ST	Q14654	KCNJ11	Q13557	CAMK2D	T224	R221L	221	Missense	distal	-3	no	73.333	51.498	PhosphoSitePlus	ICGC;COSMIC	37.605	Down-regulation
CAMK_CAMK2_CAMK2D_ST	Q14654	KCNJ11	Q13557	CAMK2D	T224	T223I	223	Missense	proximal	-1	no	73.333	72.373	PhosphoSitePlus	ICGC;GDSC;CCLE	37.605	Down-regulation
CAMK_CAMK2_CAMK2D_ST	Q14654	KCNJ11	Q13557	CAMK2D	T224	E227D	227	Missense	distal	3	no	73.333	60.749	PhosphoSitePlus	ICGC;COSMIC	37.605	Down-regulation
CAMK_CAMK2_CAMK2D_ST	Q14654	KCNJ11	Q13557	CAMK2D	S372	V373M	373	Missense	proximal	1	no	37.388	42.262	EPSD	ICGC;COSMIC;GDSC	37.605	Gain
CAMK_CAMK2_CAMK2D_ST	Q14654	KCNJ11	Q13557	CAMK2D	S388	S388A	388	Missense	central	0	yes	39.163	0.000	EPSD	ICGC;COSMIC	37.605	Loss
CAMK_CAMK2_CAMK2D_ST	Q14654	KCNJ11	Q13557	CAMK2D	S388	S388F	388	Missense	central	0	yes	39.163	0.000	EPSD	ICGC	37.605	Loss
CAMK_CAMK2_CAMK2D_ST	Q16625	OCLN	Q13557	CAMK2D	S25	H21R	21	Missense	distal	-4	no	46.884	47.818	EPSD	ICGC;COSMIC	37.605	Up-regulation
CAMK_CAMK2_CAMK2D_ST	Q16625	OCLN	Q13557	CAMK2D	S25	P24L	24	Missense	proximal	-1	no	46.884	48.659	EPSD	ICGC	37.605	Up-regulation
CAMK_CAMK2_CAMK2D_ST	O15084	ANKRD28	Q13557	CAMK2D	T360	T360K	360	Missense	central	0	yes	41.180	0.000	EPSD	ICGC;COSMIC	37.605	Loss
CAMK_CAMK2_CAMK2D_ST	O15084	ANKRD28	Q13557	CAMK2D	T360	A366T	366	Missense	distal	6	no	41.180	37.587	EPSD	ICGC;COSMIC	37.605	Loss
CAMK_CAMK2_CAMK2D_ST	O15084	ANKRD28	Q13557	CAMK2D	S1011	T1006N	1006	Missense	distal	-5	no	71.759	72.022	PhosphoSitePlus	ICGC	37.605	Up-regulation
AGC_GRK_GRK_GRK6_ST	P07550	ADRB2	P43250	GRK6	S355	N352H	352	Missense	distal	-3	no	113.178	105.599	PhosphoSitePlus;EPSD	ICGC	74.824	Down-regulation
AGC_GRK_GRK_GRK6_ST	P07550	ADRB2	P43250	GRK6	S356	N352H	352	Missense	distal	-4	no	113.461	115.088	EPSD;PhosphoSitePlus	ICGC	74.824	Up-regulation
AGC_GRK_GRK_GRK6_ST	P07550	ADRB2	P43250	GRK6	S364	S364R	364	Missense	central	0	yes	76.187	0.000	EPSD	ICGC	74.824	Loss
AGC_GRK_GRK_GRK6_ST	P43250	GRK6	P43250	GRK6	S484	G488D	488	Missense	distal	4	no	111.423	111.512	PhosphoSitePlus;EPSD	ICGC;COSMIC	74.824	Up-regulation
AGC_GRK_GRK_GRK6_ST	P43250	GRK6	P43250	GRK6	S484	K487N	487	Missense	distal	3	no	111.423	107.378	PhosphoSitePlus;EPSD	ICGC;COSMIC	74.824	Down-regulation
AGC_GRK_GRK_GRK6_ST	P43250	GRK6	P43250	GRK6	T485	G488D	488	Missense	distal	3	no	110.654	113.042	EPSD;PhosphoSitePlus	ICGC;COSMIC	74.824	Up-regulation
AGC_GRK_GRK_GRK6_ST	P43250	GRK6	P43250	GRK6	T485	K487N	487	Missense	proximal	2	no	110.654	109.395	EPSD;PhosphoSitePlus	ICGC;COSMIC	74.824	Down-regulation
AGC_GRK_GRK_GRK6_ST	Q15722	LTB4R	P43250	GRK6	T308	L305R	305	Missense	distal	-3	no	117.203	131.875	PhosphoSitePlus	ICGC	74.824	Up-regulation
STE_STE20_YSK_STK25_ST	Q9BSQ5	CCM2	O00506	STK25	S251	S245Y	245	Missense	distal	-6	no	1.793	1.860	EPSD	ICGC;COSMIC	1.379	Up-regulation
STE_STE20_YSK_STK25_ST	Q9BSQ5	CCM2	O00506	STK25	S251	L246M	246	Missense	distal	-5	no	1.793	1.654	EPSD	ICGC	1.379	Down-regulation
STE_STE20_YSK_STK25_ST	Q9BUL8	PDCD10	O00506	STK25	S39	L33Q	33	Missense	distal	-6	no	5.877	5.865	EPSD;PhosphoSitePlus	ICGC;COSMIC	1.379	Down-regulation
STE_STE20_YSK_STK25_ST	Q9BUL8	PDCD10	O00506	STK25	T43	A47T	47	Missense	distal	4	no	5.560	5.602	PhosphoSitePlus;EPSD	ICGC	1.379	Up-regulation
Other_WNK_WNK3_ST	Q9H4A3	WNK1	Q9BYP7	WNK3	T72	A70V	70	Missense	proximal	-2	no	4.561	4.183	EPSD	ICGC;COSMIC	2.233	Down-regulation
Other_WNK_WNK3_ST	Q9H4A3	WNK1	Q9BYP7	WNK3	T72	G67E	67	Missense	distal	-5	no	4.561	4.791	EPSD	ICGC	2.233	Up-regulation
Other_WNK_WNK3_ST	Q9H4A3	WNK1	Q9BYP7	WNK3	T72	R66S	66	Missense	distal	-6	no	4.561	4.351	EPSD	ICGC;GDSC;CCLE	2.233	Down-regulation
Other_WNK_WNK3_ST	Q9H4A3	WNK1	Q9BYP7	WNK3	T209	E206D	206	Missense	distal	-3	no	2.846	2.810	EPSD	ICGC;COSMIC	2.233	Down-regulation
Other_WNK_WNK3_ST	Q9H4A3	WNK1	Q9BYP7	WNK3	S597	S596F	596	Missense	proximal	-1	no	3.602	3.591	EPSD	ICGC;COSMIC	2.233	Down-regulation
Other_WNK_WNK3_ST	Q9UHW9	SLC12A6	Q9BYP7	WNK3	S96	T98N	98	Missense	proximal	2	no	6.778	6.876	EPSD;PhosphoSitePlus	ICGC	2.233	Up-regulation
Other_WNK_WNK3_ST	Q9UHW9	SLC12A6	Q9BYP7	WNK3	T991	Q996K	996	Missense	distal	5	no	7.155	7.161	EPSD;PhosphoSitePlus	ICGC	2.233	Up-regulation
TK_InsR_IGF1R_Y	P35568	IRS1	P08069	IGF1R	Y47	E48K	48	Missense	proximal	1	no	3.370	3.494	EPSD	ICGC;COSMIC	3.025	Up-regulation
TK_InsR_IGF1R_Y	P35568	IRS1	P08069	IGF1R	Y431	D437Y	437	Missense	distal	6	no	4.578	4.515	EPSD	ICGC;COSMIC	3.025	Down-regulation
TK_InsR_IGF1R_Y	P35568	IRS1	P08069	IGF1R	Y632	P634S	634	Missense	proximal	2	no	7.153	7.739	EPSD;PhosphoSitePlus	ICGC;COSMIC	3.025	Up-regulation
TK_InsR_IGF1R_Y	P35568	IRS1	P08069	IGF1R	Y632	Y632C	632	Missense	central	0	yes	7.153	0.000	EPSD;PhosphoSitePlus	ICGC;COSMIC	3.025	Loss
TK_InsR_IGF1R_Y	P35568	IRS1	P08069	IGF1R	Y632	K627N	627	Missense	distal	-5	no	7.153	7.054	EPSD;PhosphoSitePlus	ICGC;COSMIC	3.025	Down-regulation
TK_InsR_IGF1R_Y	P35568	IRS1	P08069	IGF1R	Y662	D658E	658	Missense	distal	-4	no	5.753	5.760	EPSD;PhosphoSitePlus	ICGC	3.025	Up-regulation
TK_InsR_IGF1R_Y	P35568	IRS1	P08069	IGF1R	Y662	P667H	667	Missense	distal	5	no	5.753	5.658	EPSD;PhosphoSitePlus	ICGC;COSMIC	3.025	Down-regulation
TK_InsR_IGF1R_Y	P35568	IRS1	P08069	IGF1R	Y732	L725I	725	Missense	distal	-7	no	3.821	3.733	EPSD;PhosphoSitePlus	ICGC	3.025	Down-regulation
TK_InsR_IGF1R_Y	P35568	IRS1	P08069	IGF1R	Y750	G752S	752	Missense	proximal	2	no	2.968	4.602	EPSD	ICGC;COSMIC	3.025	Gain
TK_InsR_IGF1R_Y	P35568	IRS1	P08069	IGF1R	Y750	D748N	748	Missense	proximal	-2	no	2.968	3.074	EPSD	ICGC	3.025	Gain
TK_InsR_IGF1R_Y	P35568	IRS1	P08069	IGF1R	Y941	E939D	939	Missense	proximal	-2	no	5.533	5.531	EPSD;PhosphoSitePlus	ICGC	3.025	Down-regulation
TK_InsR_IGF1R_Y	P35568	IRS1	P08069	IGF1R	Y1001	D1003N	1003	Missense	proximal	2	no	3.560	4.398	EPSD	ICGC;COSMIC	3.025	Up-regulation
TK_InsR_IGF1R_Y	P08069	IGF1R	P08069	IGF1R	Y1165	G1169W	1169	Missense	distal	4	no	5.207	4.837	EPSD;PhosphoSitePlus	ICGC;COSMIC	3.025	Down-regulation
TK_InsR_IGF1R_Y	P08069	IGF1R	P08069	IGF1R	Y1166	G1169W	1169	Missense	distal	3	no	5.167	4.892	EPSD;PhosphoSitePlus	ICGC;COSMIC	3.025	Down-regulation
TK_InsR_IGF1R_Y	O15530	PDPK1	P08069	IGF1R	Y373	S366L	366	Missense	distal	-7	no	4.041	4.731	EPSD;PhosphoSitePlus	ICGC	3.025	Up-regulation
TK_InsR_IGF1R_Y	Q03431	PTH1R	P08069	IGF1R	Y494	R488H	488	Missense	distal	-6	no	4.394	4.364	PhosphoSitePlus	ICGC	3.025	Down-regulation
TK_InsR_IGF1R_Y	Q03431	PTH1R	P08069	IGF1R	Y494	S493N	493	Missense	proximal	-1	no	4.394	4.380	PhosphoSitePlus	ICGC;COSMIC	3.025	Down-regulation
TK_InsR_IGF1R_Y	Q03431	PTH1R	P08069	IGF1R	Y494	M499I	499	Missense	distal	5	no	4.394	4.284	PhosphoSitePlus	ICGC	3.025	Down-regulation
TK_InsR_IGF1R_Y	Q03431	PTH1R	P08069	IGF1R	Y496	S493N	493	Missense	distal	-3	no	3.200	3.004	EPSD	ICGC;COSMIC	3.025	Loss
TK_InsR_IGF1R_Y	Q03431	PTH1R	P08069	IGF1R	Y496	M499I	499	Missense	distal	3	no	3.200	2.616	EPSD	ICGC	3.025	Loss
TK_InsR_IGF1R_Y	P07355	ANXA2	P08069	IGF1R	Y24	T19A	19	Missense	distal	-5	no	3.818	3.854	PhosphoSitePlus	ICGC;COSMIC	3.025	Up-regulation
TK_InsR_IGF1R_Y	P07355	ANXA2	P08069	IGF1R	Y24	S18C	18	Missense	distal	-6	no	3.818	3.951	PhosphoSitePlus	ICGC;COSMIC	3.025	Up-regulation
TK_InsR_IGF1R_Y	P07355	ANXA2	P08069	IGF1R	Y24	Y30C	30	Missense	distal	6	no	3.818	3.851	PhosphoSitePlus	ICGC;COSMIC	3.025	Up-regulation
TK_InsR_IGF1R_Y	P07355	ANXA2	P08069	IGF1R	Y24	P21T	21	Missense	distal	-3	no	3.818	3.633	PhosphoSitePlus	ICGC;COSMIC	3.025	Down-regulation
TK_InsR_IGF1R_Y	P07355	ANXA2	P08069	IGF1R	Y24	S18F	18	Missense	distal	-6	no	3.818	4.001	PhosphoSitePlus	ICGC	3.025	Up-regulation
TK_InsR_IGF1R_Y	P07355	ANXA2	P08069	IGF1R	Y199	Y199C	199	Missense	central	0	yes	3.719	0.000	EPSD	ICGC;COSMIC	3.025	Loss
TK_InsR_IGF1R_Y	P07355	ANXA2	P08069	IGF1R	Y199	R196W	196	Missense	distal	-3	no	3.719	3.336	EPSD	ICGC;COSMIC	3.025	Down-regulation
TK_InsR_IGF1R_Y	P07355	ANXA2	P08069	IGF1R	Y199	R196L	196	Missense	distal	-3	no	3.719	3.203	EPSD	ICGC;COSMIC	3.025	Down-regulation
TK_InsR_IGF1R_Y	P07355	ANXA2	P08069	IGF1R	Y199	R196Q	196	Missense	distal	-3	no	3.719	3.649	EPSD	ICGC;COSMIC	3.025	Down-regulation
TK_InsR_IGF1R_Y	P07355	ANXA2	P08069	IGF1R	Y199	D200Y	200	Missense	proximal	1	no	3.719	3.777	EPSD	ICGC;COSMIC	3.025	Up-regulation
TK_InsR_IGF1R_Y	P07355	ANXA2	P08069	IGF1R	Y199	A201T	201	Missense	proximal	2	no	3.719	3.775	EPSD	ICGC;COSMIC	3.025	Up-regulation
TK_InsR_IGF1R_Y	P07355	ANXA2	P08069	IGF1R	Y199	A195D	195	Missense	distal	-4	no	3.719	3.712	EPSD	ICGC;COSMIC	3.025	Down-regulation
TK_InsR_IGF1R_Y	P07355	ANXA2	P08069	IGF1R	Y232	S236N	236	Missense	distal	4	no	3.225	3.114	EPSD	ICGC;COSMIC	3.025	Down-regulation
TK_InsR_IGF1R_Y	P07355	ANXA2	P08069	IGF1R	Y232	Q226K	226	Missense	distal	-6	no	3.225	3.232	EPSD	ICGC	3.025	Up-regulation
TK_InsR_IGF1R_Y	P07355	ANXA2	P08069	IGF1R	Y232	D230H	230	Missense	proximal	-2	no	3.225	2.949	EPSD	ICGC;COSMIC	3.025	Loss
TK_InsR_IGF1R_Y	P07355	ANXA2	P08069	IGF1R	Y232	P237H	237	Missense	distal	5	no	3.225	3.130	EPSD	ICGC;COSMIC	3.025	Down-regulation
TK_InsR_IGF1R_Y	P07355	ANXA2	P08069	IGF1R	Y232	R231M	231	Missense	proximal	-1	no	3.225	3.256	EPSD	ICGC;COSMIC	3.025	Up-regulation
TK_InsR_IGF1R_Y	P07355	ANXA2	P08069	IGF1R	Y238	S236N	236	Missense	proximal	-2	no	3.332	3.074	EPSD	ICGC;COSMIC	3.025	Down-regulation
TK_InsR_IGF1R_Y	P07355	ANXA2	P08069	IGF1R	Y238	R245S	245	Missense	distal	7	no	3.332	3.277	EPSD	ICGC	3.025	Down-regulation
TK_InsR_IGF1R_Y	P07355	ANXA2	P08069	IGF1R	Y238	P237H	237	Missense	proximal	-1	no	3.332	3.249	EPSD	ICGC;COSMIC	3.025	Down-regulation
TK_InsR_IGF1R_Y	P07355	ANXA2	P08069	IGF1R	Y238	R231M	231	Missense	distal	-7	no	3.332	3.124	EPSD	ICGC;COSMIC	3.025	Down-regulation
TK_InsR_IGF1R_Y	P07355	ANXA2	P08069	IGF1R	Y238	M240T	240	Missense	proximal	2	no	3.332	3.836	EPSD	ICGC;COSMIC	3.025	Up-regulation
TK_InsR_IGF1R_Y	P12004	PCNA	P08069	IGF1R	Y60	S54F	54	Missense	distal	-6	no	4.859	5.043	EPSD;PhosphoSitePlus	ICGC	3.025	Up-regulation
TK_InsR_IGF1R_Y	P12004	PCNA	P08069	IGF1R	Y114	Q108K	108	Missense	distal	-6	no	3.957	3.964	EPSD	ICGC	3.025	Up-regulation
TK_InsR_IGF1R_Y	P12004	PCNA	P08069	IGF1R	Y114	N107K	107	Missense	distal	-7	no	3.957	4.147	EPSD	ICGC	3.025	Up-regulation
TK_InsR_IGF1R_Y	P12004	PCNA	P08069	IGF1R	Y133	S134R	134	Missense	proximal	1	no	3.886	3.555	PhosphoSitePlus;EPSD	ICGC	3.025	Down-regulation
TK_InsR_IGF1R_Y	P12004	PCNA	P08069	IGF1R	Y133	P129S	129	Missense	distal	-4	no	3.886	3.911	PhosphoSitePlus;EPSD	ICGC	3.025	Up-regulation
TK_InsR_IGF1R_Y	P78324	SIRPA	P08069	IGF1R	Y470	D472Y	472	Missense	proximal	2	no	4.343	3.605	EPSD;PhosphoSitePlus	ICGC	3.025	Down-regulation
TK_InsR_IGF1R_Y	P78324	SIRPA	P08069	IGF1R	Y470	A463T	463	Missense	distal	-7	no	4.343	4.216	EPSD;PhosphoSitePlus	ICGC;GDSC	3.025	Down-regulation
TK_InsR_IGF1R_Y	P78324	SIRPA	P08069	IGF1R	Y496	F493L	493	Missense	distal	-3	no	3.937	4.020	PhosphoSitePlus;EPSD	ICGC	3.025	Up-regulation
TK_InsR_IGF1R_Y	P78324	SIRPA	P08069	IGF1R	Y496	A497S	497	Missense	proximal	1	no	3.937	3.823	PhosphoSitePlus;EPSD	ICGC	3.025	Down-regulation
TK_InsR_IGF1R_Y	P78324	SIRPA	P08069	IGF1R	Y496	A497T	497	Missense	proximal	1	no	3.937	3.560	PhosphoSitePlus;EPSD	ICGC;COSMIC	3.025	Down-regulation
TK_InsR_IGF1R_Y	P78324	SIRPA	P08069	IGF1R	Y496	P502L	502	Missense	distal	6	no	3.937	3.926	PhosphoSitePlus;EPSD	ICGC;COSMIC	3.025	Down-regulation
TKL_MLK_MLK_MAP3K10_ST	Q92630	DYRK2	Q02779	MAP3K10	S30	R25L	25	Missense	distal	-5	no	2.138	2.079	EPSD	ICGC	2.080	Loss
TKL_MLK_MLK_MAP3K10_ST	Q92630	DYRK2	Q02779	MAP3K10	S30	P31Q	31	Missense	proximal	1	no	2.138	-0.269	EPSD	ICGC;COSMIC	2.080	Loss
TKL_MLK_MLK_MAP3K10_ST	Q92630	DYRK2	Q02779	MAP3K10	S48	V42L	42	Missense	distal	-6	no	2.449	2.521	EPSD	ICGC	2.080	Up-regulation
TKL_MLK_MLK_MAP3K10_ST	Q92630	DYRK2	Q02779	MAP3K10	S48	S48P	48	Missense	central	0	yes	2.449	0.000	EPSD	ICGC;COSMIC	2.080	Loss
TKL_MLK_MLK_MAP3K10_ST	Q92630	DYRK2	Q02779	MAP3K10	T381	R378L	378	Missense	distal	-3	no	5.704	5.631	PhosphoSitePlus;EPSD	ICGC;COSMIC	2.080	Down-regulation
TKL_MLK_MLK_MAP3K10_ST	Q92630	DYRK2	Q02779	MAP3K10	T381	Y380H	380	Missense	proximal	-1	no	5.704	5.708	PhosphoSitePlus;EPSD	ICGC;COSMIC	2.080	Up-regulation
TKL_MLK_MLK_MAP3K10_ST	Q92630	DYRK2	Q02779	MAP3K10	T381	Q377H	377	Missense	distal	-4	no	5.704	5.725	PhosphoSitePlus;EPSD	ICGC	2.080	Up-regulation
TKL_MLK_MLK_MAP3K10_ST	Q92630	DYRK2	Q02779	MAP3K10	T381	H376P	376	Missense	distal	-5	no	5.704	5.794	PhosphoSitePlus;EPSD	ICGC;COSMIC	2.080	Up-regulation
TKL_MLK_MLK_MAP3K10_ST	Q92630	DYRK2	Q02779	MAP3K10	T381	R386C	386	Missense	distal	5	no	5.704	5.586	PhosphoSitePlus;EPSD	ICGC;COSMIC	2.080	Down-regulation
TKL_MLK_MLK_MAP3K10_ST	Q92630	DYRK2	Q02779	MAP3K10	S385	R378L	378	Missense	distal	-7	no	3.184	3.263	EPSD	ICGC;COSMIC	2.080	Up-regulation
TKL_MLK_MLK_MAP3K10_ST	Q92630	DYRK2	Q02779	MAP3K10	S385	Y380H	380	Missense	distal	-5	no	3.184	3.193	EPSD	ICGC;COSMIC	2.080	Up-regulation
TKL_MLK_MLK_MAP3K10_ST	Q92630	DYRK2	Q02779	MAP3K10	S385	R386C	386	Missense	proximal	1	no	3.184	3.381	EPSD	ICGC;COSMIC	2.080	Up-regulation
TKL_MLK_MLK_MAP3K10_ST	Q92630	DYRK2	Q02779	MAP3K10	S449	V456L	456	Missense	distal	7	no	6.181	6.329	EPSD;PhosphoSitePlus	ICGC	2.080	Up-regulation
TKL_MLK_MLK_MAP3K10_ST	Q92630	DYRK2	Q02779	MAP3K10	S471	S471L	471	Missense	central	0	yes	2.994	0.000	EPSD	ICGC;COSMIC	2.080	Loss
TKL_MLK_MLK_MAP3K10_ST	Q92630	DYRK2	Q02779	MAP3K10	T525	R531Q	531	Missense	distal	6	no	2.710	2.800	EPSD	ICGC;COSMIC	2.080	Up-regulation
TKL_MLK_MLK_MAP3K10_ST	P15923	TCF3	Q02779	MAP3K10	S39	A41T	41	Missense	proximal	2	no	2.468	2.610	EPSD	ICGC;COSMIC	2.080	Up-regulation
TKL_MLK_MLK_MAP3K10_ST	P15923	TCF3	Q02779	MAP3K10	S39	G46A	46	Missense	distal	7	no	2.468	2.304	EPSD	ICGC	2.080	Down-regulation
TKL_MLK_MLK_MAP3K10_ST	P15923	TCF3	Q02779	MAP3K10	S139	P140S	140	Missense	proximal	1	no	2.922	-0.041	EPSD	ICGC;CCLE	2.080	Loss
TKL_MLK_MLK_MAP3K10_ST	P15923	TCF3	Q02779	MAP3K10	S139	G136W	136	Missense	distal	-3	no	2.922	3.254	EPSD	ICGC;COSMIC	2.080	Up-regulation
TKL_MLK_MLK_MAP3K10_ST	P15923	TCF3	Q02779	MAP3K10	S139	K144Q	144	Missense	distal	5	no	2.922	3.019	EPSD	ICGC;COSMIC	2.080	Up-regulation
TKL_MLK_MLK_MAP3K10_ST	P15923	TCF3	Q02779	MAP3K10	T168	A162E	162	Missense	distal	-6	no	2.130	2.239	EPSD	ICGC	2.080	Up-regulation
TKL_MLK_MLK_MAP3K10_ST	P15923	TCF3	Q02779	MAP3K10	T168	Q169K	169	Missense	proximal	1	no	2.130	3.302	EPSD	ICGC	2.080	Up-regulation
TKL_MLK_MLK_MAP3K10_ST	P15923	TCF3	Q02779	MAP3K10	S229	A234V	234	Missense	distal	5	no	1.939	2.145	EPSD	ICGC	2.080	Gain
TKL_MLK_MLK_MAP3K10_ST	P15923	TCF3	Q02779	MAP3K10	S305	G302C	302	Missense	distal	-3	no	2.628	2.778	EPSD	ICGC;COSMIC	2.080	Up-regulation
TKL_MLK_MLK_MAP3K10_ST	P15923	TCF3	Q02779	MAP3K10	S305	G303S	303	Missense	proximal	-2	no	2.628	2.715	EPSD	ICGC;COSMIC;CCLE	2.080	Up-regulation
TKL_MLK_MLK_MAP3K10_ST	P15923	TCF3	Q02779	MAP3K10	T308	G302C	302	Missense	distal	-6	no	3.595	3.718	EPSD	ICGC;COSMIC	2.080	Up-regulation
TKL_MLK_MLK_MAP3K10_ST	P15923	TCF3	Q02779	MAP3K10	T308	A314V	314	Missense	distal	6	no	3.595	3.563	EPSD	ICGC	2.080	Down-regulation
TKL_MLK_MLK_MAP3K10_ST	P15923	TCF3	Q02779	MAP3K10	T308	G303S	303	Missense	distal	-5	no	3.595	3.474	EPSD	ICGC;COSMIC;CCLE	2.080	Down-regulation
TKL_MLK_MLK_MAP3K10_ST	P15923	TCF3	Q02779	MAP3K10	S352	S359C	359	Missense	distal	7	no	5.668	5.889	EPSD;PhosphoSitePlus	ICGC	2.080	Up-regulation
TKL_MLK_MLK_MAP3K10_ST	P15923	TCF3	Q02779	MAP3K10	S352	S359F	359	Missense	distal	7	no	5.668	5.966	EPSD;PhosphoSitePlus	ICGC;COSMIC	2.080	Up-regulation
TKL_MLK_MLK_MAP3K10_ST	P15923	TCF3	Q02779	MAP3K10	T355	S359C	359	Missense	distal	4	no	5.965	5.891	EPSD;PhosphoSitePlus	ICGC	2.080	Down-regulation
TKL_MLK_MLK_MAP3K10_ST	P15923	TCF3	Q02779	MAP3K10	T355	S359F	359	Missense	distal	4	no	5.965	5.817	EPSD;PhosphoSitePlus	ICGC;COSMIC	2.080	Down-regulation
TKL_MLK_MLK_MAP3K10_ST	P15923	TCF3	Q02779	MAP3K10	S359	S359C	359	Missense	central	0	yes	6.457	0.000	PhosphoSitePlus;EPSD	ICGC	2.080	Loss
TKL_MLK_MLK_MAP3K10_ST	P15923	TCF3	Q02779	MAP3K10	S359	S359F	359	Missense	central	0	yes	6.457	0.000	PhosphoSitePlus;EPSD	ICGC;COSMIC	2.080	Loss
TKL_MLK_MLK_MAP3K10_ST	P15923	TCF3	Q02779	MAP3K10	S379	D383Y	383	Missense	distal	4	no	5.985	5.990	EPSD;PhosphoSitePlus	ICGC;COSMIC	2.080	Up-regulation
TKL_MLK_MLK_MAP3K10_ST	P15923	TCF3	Q02779	MAP3K10	S379	L386I	386	Missense	distal	7	no	5.985	5.509	EPSD;PhosphoSitePlus	ICGC;COSMIC	2.080	Down-regulation
AGC_DMPK_GEK_DMPK_ST	P11831	SRF	Q09013	DMPK	T217	S221L	221	Missense	distal	4	no	2.565	2.560	EPSD	ICGC;COSMIC	2.483	Down-regulation
TKL_STKR_STKR2_TGFBR2_ST	P36897	TGFBR1	P37173	TGFBR2	T185	D179Y	179	Missense	distal	-6	no	1.780	1.748	PhosphoSitePlus;EPSD	ICGC;COSMIC	0.983	Down-regulation
TKL_STKR_STKR2_TGFBR2_ST	P36897	TGFBR1	P37173	TGFBR2	T185	T186A	186	Missense	proximal	1	no	1.780	1.813	PhosphoSitePlus;EPSD	ICGC;COSMIC	0.983	Up-regulation
TKL_STKR_STKR2_TGFBR2_ST	P36897	TGFBR1	P37173	TGFBR2	T186	D179Y	179	Missense	distal	-7	no	1.939	1.938	EPSD;PhosphoSitePlus	ICGC;COSMIC	0.983	Down-regulation
TKL_STKR_STKR2_TGFBR2_ST	P36897	TGFBR1	P37173	TGFBR2	T186	T186A	186	Missense	central	0	yes	1.939	0.000	EPSD;PhosphoSitePlus	ICGC;COSMIC	0.983	Loss
TKL_STKR_STKR2_TGFBR2_ST	P36897	TGFBR1	P37173	TGFBR2	S187	T186A	186	Missense	proximal	-1	no	2.011	1.975	EPSD;PhosphoSitePlus	ICGC;COSMIC	0.983	Down-regulation
TKL_STKR_STKR2_TGFBR2_ST	P36897	TGFBR1	P37173	TGFBR2	S189	T186A	186	Missense	distal	-3	no	1.713	1.694	EPSD;PhosphoSitePlus	ICGC;COSMIC	0.983	Down-regulation
TKL_STKR_STKR2_TGFBR2_ST	P36897	TGFBR1	P37173	TGFBR2	S191	T186A	186	Missense	distal	-5	no	1.909	1.879	EPSD;PhosphoSitePlus	ICGC;COSMIC	0.983	Down-regulation
TKL_STKR_STKR2_TGFBR2_ST	O75604	USP2	P37173	TGFBR2	S42	E45Q	45	Missense	distal	3	no	0.957	1.022	EPSD	ICGC;COSMIC	0.983	Gain
TKL_STKR_STKR2_TGFBR2_ST	O75604	USP2	P37173	TGFBR2	S169	S169N	169	Missense	central	0	yes	1.011	0.000	EPSD	ICGC;COSMIC	0.983	Loss
TKL_STKR_STKR2_TGFBR2_ST	O75604	USP2	P37173	TGFBR2	S169	R176C	176	Missense	distal	7	no	1.011	1.005	EPSD	ICGC;COSMIC;CCLE	0.983	Down-regulation
TKL_STKR_STKR2_TGFBR2_ST	O75604	USP2	P37173	TGFBR2	S169	D162Y	162	Missense	distal	-7	no	1.011	1.010	EPSD	ICGC;COSMIC	0.983	Down-regulation
TKL_STKR_STKR2_TGFBR2_ST	O75604	USP2	P37173	TGFBR2	S169	R168H	168	Missense	proximal	-1	no	1.011	1.014	EPSD	ICGC;COSMIC	0.983	Up-regulation
TKL_STKR_STKR2_TGFBR2_ST	O75604	USP2	P37173	TGFBR2	S169	R174Q	174	Missense	distal	5	no	1.011	1.016	EPSD	ICGC	0.983	Up-regulation
TKL_STKR_STKR2_TGFBR2_ST	O75604	USP2	P37173	TGFBR2	S169	A173S	173	Missense	distal	4	no	1.011	0.987	EPSD	ICGC;COSMIC	0.983	Down-regulation
TKL_STKR_STKR2_TGFBR2_ST	O75604	USP2	P37173	TGFBR2	T175	L179I	179	Missense	distal	4	no	1.091	1.060	EPSD	ICGC;COSMIC	0.983	Down-regulation
TKL_STKR_STKR2_TGFBR2_ST	O75604	USP2	P37173	TGFBR2	T175	S169N	169	Missense	distal	-6	no	1.091	1.097	EPSD	ICGC;COSMIC	0.983	Up-regulation
TKL_STKR_STKR2_TGFBR2_ST	O75604	USP2	P37173	TGFBR2	T175	R176C	176	Missense	proximal	1	no	1.091	1.103	EPSD	ICGC;COSMIC;CCLE	0.983	Up-regulation
TKL_STKR_STKR2_TGFBR2_ST	O75604	USP2	P37173	TGFBR2	T175	R168H	168	Missense	distal	-7	no	1.091	1.082	EPSD	ICGC;COSMIC	0.983	Down-regulation
TKL_STKR_STKR2_TGFBR2_ST	O75604	USP2	P37173	TGFBR2	T175	R174Q	174	Missense	proximal	-1	no	1.091	1.105	EPSD	ICGC	0.983	Up-regulation
TKL_STKR_STKR2_TGFBR2_ST	O75604	USP2	P37173	TGFBR2	T175	A173S	173	Missense	proximal	-2	no	1.091	1.116	EPSD	ICGC;COSMIC	0.983	Up-regulation
TKL_STKR_STKR2_TGFBR2_ST	O75604	USP2	P37173	TGFBR2	S207	N201K	201	Missense	distal	-6	no	1.937	1.933	PhosphoSitePlus;EPSD	ICGC;COSMIC	0.983	Down-regulation
TKL_STKR_STKR2_TGFBR2_ST	O75604	USP2	P37173	TGFBR2	S207	Y202N	202	Missense	distal	-5	no	1.937	1.978	PhosphoSitePlus;EPSD	ICGC;COSMIC	0.983	Up-regulation
TKL_STKR_STKR2_TGFBR2_ST	O75604	USP2	P37173	TGFBR2	S225	P226T	226	Missense	proximal	1	no	1.792	1.811	EPSD;PhosphoSitePlus	ICGC	0.983	Up-regulation
TKL_STKR_STKR2_TGFBR2_ST	O75604	USP2	P37173	TGFBR2	S225	E222K	222	Missense	distal	-3	no	1.792	1.691	EPSD;PhosphoSitePlus	ICGC;COSMIC	0.983	Down-regulation
TKL_STKR_STKR2_TGFBR2_ST	P17813	ENG	P37173	TGFBR2	S634	E636A	636	Missense	proximal	2	no	1.209	1.135	EPSD;PhosphoSitePlus	ICGC;COSMIC	0.983	Down-regulation
TKL_STKR_STKR2_TGFBR2_ST	P17813	ENG	P37173	TGFBR2	S634	A631T	631	Missense	distal	-3	no	1.209	1.227	EPSD;PhosphoSitePlus	ICGC	0.983	Up-regulation
TKL_STKR_STKR2_TGFBR2_ST	P17813	ENG	P37173	TGFBR2	S634	A628V	628	Missense	distal	-6	no	1.209	1.231	EPSD;PhosphoSitePlus	ICGC	0.983	Up-regulation
TKL_STKR_STKR2_TGFBR2_ST	P17813	ENG	P37173	TGFBR2	S635	E636A	636	Missense	proximal	1	no	1.059	1.026	PhosphoSitePlus;EPSD	ICGC;COSMIC	0.983	Down-regulation
TKL_STKR_STKR2_TGFBR2_ST	P17813	ENG	P37173	TGFBR2	S635	A631T	631	Missense	distal	-4	no	1.059	1.010	PhosphoSitePlus;EPSD	ICGC	0.983	Down-regulation
TKL_STKR_STKR2_TGFBR2_ST	P17813	ENG	P37173	TGFBR2	S635	A628V	628	Missense	distal	-7	no	1.059	1.057	PhosphoSitePlus;EPSD	ICGC	0.983	Down-regulation
CMGC_CLK_CLK1_ST	P00519	ABL1	P49759	CLK1	S157	R152C	152	Missense	distal	-5	no	58.424	46.121	EPSD	ICGC;COSMIC	52.547	Loss
CMGC_CLK_CLK1_ST	P00519	ABL1	P49759	CLK1	S157	S164L	164	Missense	distal	7	no	58.424	56.309	EPSD	ICGC;CCLE	52.547	Down-regulation
CMGC_CLK_CLK1_ST	P00519	ABL1	P49759	CLK1	S157	R161M	161	Missense	distal	4	no	58.424	59.157	EPSD	ICGC;COSMIC	52.547	Up-regulation
CMGC_CLK_CLK1_ST	P00519	ABL1	P49759	CLK1	S535	P529S	529	Missense	distal	-6	no	41.050	56.545	EPSD	ICGC;COSMIC	52.547	Gain
CMGC_CLK_CLK1_ST	P00519	ABL1	P49759	CLK1	T613	R617C	617	Missense	distal	4	no	57.730	59.806	EPSD	ICGC;COSMIC	52.547	Up-regulation
CMGC_CLK_CLK1_ST	P00519	ABL1	P49759	CLK1	T613	R617H	617	Missense	distal	4	no	57.730	60.249	EPSD	ICGC;COSMIC	52.547	Up-regulation
CMGC_CLK_CLK1_ST	P00519	ABL1	P49759	CLK1	T613	K607N	607	Missense	distal	-6	no	57.730	55.542	EPSD	ICGC;COSMIC	52.547	Down-regulation
CMGC_CLK_CLK1_ST	P00519	ABL1	P49759	CLK1	S620	R617C	617	Missense	distal	-3	no	68.910	42.267	EPSD	ICGC;COSMIC	52.547	Loss
CMGC_CLK_CLK1_ST	P00519	ABL1	P49759	CLK1	S620	R617H	617	Missense	distal	-3	no	68.910	35.996	EPSD	ICGC;COSMIC	52.547	Loss
CMGC_CLK_CLK1_ST	P00519	ABL1	P49759	CLK1	S620	M624I	624	Missense	distal	4	no	68.910	69.947	EPSD	ICGC;COSMIC	52.547	Up-regulation
CMGC_CLK_CLK1_ST	P00519	ABL1	P49759	CLK1	S642	S642G	642	Missense	central	0	yes	70.448	0.000	EPSD	ICGC	52.547	Loss
CMGC_CLK_CLK1_ST	P00519	ABL1	P49759	CLK1	S659	G665V	665	Missense	distal	6	no	53.942	54.927	EPSD	ICGC;COSMIC	52.547	Up-regulation
CMGC_CLK_CLK1_ST	P00519	ABL1	P49759	CLK1	S659	G665W	665	Missense	distal	6	no	53.942	54.643	EPSD	ICGC;COSMIC	52.547	Up-regulation
CMGC_CLK_CLK1_ST	P00519	ABL1	P49759	CLK1	S695	K688N	688	Missense	distal	-7	no	56.336	55.169	EPSD	ICGC;COSMIC	52.547	Down-regulation
CMGC_CLK_CLK1_ST	P00519	ABL1	P49759	CLK1	S695	T692M	692	Missense	distal	-3	no	56.336	38.156	EPSD	ICGC	52.547	Loss
CMGC_CLK_CLK1_ST	P00519	ABL1	P49759	CLK1	S695	G701S	701	Missense	distal	6	no	56.336	58.899	EPSD	ICGC;CCLE	52.547	Up-regulation
CMGC_CLK_CLK1_ST	P00519	ABL1	P49759	CLK1	S709	G706S	706	Missense	distal	-3	no	47.193	70.715	EPSD	ICGC;COSMIC	52.547	Gain
CMGC_CLK_CLK1_ST	P00519	ABL1	P49759	CLK1	S718	R712H	712	Missense	distal	-6	no	60.359	52.502	EPSD	ICGC;COSMIC	52.547	Loss
CMGC_CLK_CLK1_ST	P00519	ABL1	P49759	CLK1	S718	R715H	715	Missense	distal	-3	no	60.359	27.445	EPSD	ICGC;COSMIC	52.547	Loss
CMGC_CLK_CLK1_ST	P00519	ABL1	P49759	CLK1	S718	V722F	722	Missense	distal	4	no	60.359	61.468	EPSD	ICGC	52.547	Up-regulation
CMGC_CLK_CLK1_ST	P00519	ABL1	P49759	CLK1	S718	K711N	711	Missense	distal	-7	no	60.359	59.192	EPSD	ICGC;COSMIC	52.547	Down-regulation
CMGC_CLK_CLK1_ST	P00519	ABL1	P49759	CLK1	S718	R715C	715	Missense	distal	-3	no	60.359	33.716	EPSD	ICGC;CCLE	52.547	Loss
CMGC_CLK_CLK1_ST	P00519	ABL1	P49759	CLK1	T735	D728Y	728	Missense	distal	-7	no	96.105	82.809	PhosphoSitePlus	ICGC	52.547	Down-regulation
CMGC_CLK_CLK1_ST	P00519	ABL1	P49759	CLK1	T735	S742F	742	Missense	distal	7	no	96.105	93.483	PhosphoSitePlus	ICGC;COSMIC	52.547	Down-regulation
CMGC_CLK_CLK1_ST	P00519	ABL1	P49759	CLK1	S968	P961S	961	Missense	distal	-7	no	47.234	53.837	EPSD	ICGC;COSMIC	52.547	Gain
CMGC_CLK_CLK1_ST	P00519	ABL1	P49759	CLK1	S977	P971S	971	Missense	distal	-6	no	49.575	65.071	EPSD	ICGC;COSMIC	52.547	Gain
CMGC_CLK_CLK1_ST	P00519	ABL1	P49759	CLK1	S1011	R1013W	1013	Missense	proximal	2	no	56.202	55.783	EPSD	ICGC;COSMIC	52.547	Down-regulation
CMGC_CLK_CLK1_ST	P00519	ABL1	P49759	CLK1	S1011	R1013L	1013	Missense	proximal	2	no	56.202	55.540	EPSD	ICGC	52.547	Down-regulation
CMGC_CLK_CLK1_ST	P00519	ABL1	P49759	CLK1	S1011	T1008I	1008	Missense	distal	-3	no	56.202	47.969	EPSD	ICGC;COSMIC	52.547	Loss
CMGC_CLK_CLK1_ST	P00519	ABL1	P49759	CLK1	S1011	R1009Q	1009	Missense	proximal	-2	no	56.202	56.317	EPSD	ICGC;COSMIC	52.547	Up-regulation
CMGC_CLK_CLK1_ST	P00519	ABL1	P49759	CLK1	S1011	R1016C	1016	Missense	distal	5	no	56.202	53.480	EPSD	ICGC;COSMIC	52.547	Down-regulation
CMGC_CLK_CLK1_ST	P00519	ABL1	P49759	CLK1	S1106	P1101Q	1101	Missense	distal	-5	no	41.846	53.316	EPSD	ICGC;COSMIC	52.547	Gain
CMGC_CLK_CLK1_ST	Q96I25	RBM17	P49759	CLK1	S48	R44M	44	Missense	distal	-4	no	95.061	94.585	EPSD;PhosphoSitePlus	ICGC;COSMIC	52.547	Down-regulation
CMGC_CLK_CLK1_ST	Q96I25	RBM17	P49759	CLK1	S48	A52S	52	Missense	distal	4	no	95.061	93.435	EPSD;PhosphoSitePlus	ICGC;COSMIC	52.547	Down-regulation
CMGC_CLK_CLK1_ST	Q96I25	RBM17	P49759	CLK1	S48	S42N	42	Missense	distal	-6	no	95.061	92.582	EPSD;PhosphoSitePlus	ICGC	52.547	Down-regulation
CMGC_CLK_CLK1_ST	Q96I25	RBM17	P49759	CLK1	S62	D65Y	65	Missense	distal	3	no	98.929	96.828	EPSD;PhosphoSitePlus	ICGC	52.547	Down-regulation
CMGC_CLK_CLK1_ST	Q96I25	RBM17	P49759	CLK1	S169	A174T	174	Missense	distal	5	no	64.032	61.104	EPSD	ICGC;COSMIC	52.547	Down-regulation
CMGC_CLK_CLK1_ST	Q96I25	RBM17	P49759	CLK1	S169	A174S	174	Missense	distal	5	no	64.032	64.961	EPSD	ICGC	52.547	Up-regulation
CMGC_CLK_CLK1_ST	Q96I25	RBM17	P49759	CLK1	S222	P220L	220	Missense	proximal	-2	no	100.524	92.110	PhosphoSitePlus;EPSD	ICGC	52.547	Down-regulation
CMGC_CLK_CLK1_ST	Q96I25	RBM17	P49759	CLK1	T224	P220L	220	Missense	distal	-4	no	68.289	68.322	EPSD	ICGC	52.547	Up-regulation
CMGC_CLK_CLK1_ST	Q96I25	RBM17	P49759	CLK1	S227	P220L	220	Missense	distal	-7	no	51.161	53.554	EPSD	ICGC	52.547	Gain
CMGC_CLK_CLK1_ST	Q96I25	RBM17	P49759	CLK1	S266	A264T	264	Missense	proximal	-2	no	96.706	91.897	EPSD;PhosphoSitePlus	ICGC	52.547	Down-regulation
CMGC_CLK_CLK1_ST	P18031	PTPN1	P49759	CLK1	S50	R45S	45	Missense	distal	-5	no	105.509	96.128	EPSD;PhosphoSitePlus	ICGC	52.547	Down-regulation
CMGC_CLK_CLK1_ST	P18031	PTPN1	P49759	CLK1	S70	A69T	69	Missense	proximal	-1	no	72.205	72.224	EPSD	ICGC	52.547	Up-regulation
CAMK_CAMKL_BRSK_BRSK2_ST	Q13131	PRKAA1	Q8IWQ3	BRSK2	T183	N189S	189	Missense	distal	6	no	9.362	9.472	PhosphoSitePlus	ICGC;COSMIC;CCLE	3.184	Up-regulation
CAMK_CAMKL_BRSK_BRSK2_ST	Q13131	PRKAA1	Q8IWQ3	BRSK2	T183	T183K	183	Missense	central	0	yes	9.362	0.000	PhosphoSitePlus	ICGC	3.184	Loss
CAMK_CAMKL_BRSK_BRSK2_ST	Q13131	PRKAA1	Q8IWQ3	BRSK2	S502	C503Y	503	Missense	proximal	1	no	3.087	3.280	EPSD	ICGC	3.184	Gain
CAMK_CAMKL_BRSK_BRSK2_ST	Q13131	PRKAA1	Q8IWQ3	BRSK2	S517	S524Y	524	Missense	distal	7	no	3.417	3.393	EPSD	ICGC;COSMIC	3.184	Down-regulation
CAMK_CAMKL_BRSK_BRSK2_ST	P49815	TSC2	Q8IWQ3	BRSK2	S946	A950S	950	Missense	distal	4	no	4.455	4.370	EPSD	ICGC	3.184	Down-regulation
CAMK_CAMKL_BRSK_BRSK2_ST	P49815	TSC2	Q8IWQ3	BRSK2	T993	R988L	988	Missense	distal	-5	no	3.697	3.716	EPSD	ICGC	3.184	Up-regulation
CAMK_CAMKL_BRSK_BRSK2_ST	P49815	TSC2	Q8IWQ3	BRSK2	T993	R988H	988	Missense	distal	-5	no	3.697	3.725	EPSD	ICGC	3.184	Up-regulation
CAMK_CAMKL_BRSK_BRSK2_ST	P49815	TSC2	Q8IWQ3	BRSK2	T993	V986M	986	Missense	distal	-7	no	3.697	4.096	EPSD	ICGC	3.184	Up-regulation
CAMK_CAMKL_BRSK_BRSK2_ST	P49815	TSC2	Q8IWQ3	BRSK2	S997	S1002F	1002	Missense	distal	5	no	4.377	4.398	EPSD	ICGC;COSMIC	3.184	Up-regulation
CAMK_CAMKL_BRSK_BRSK2_ST	P49815	TSC2	Q8IWQ3	BRSK2	S997	S1002Y	1002	Missense	distal	5	no	4.377	4.470	EPSD	ICGC;COSMIC	3.184	Up-regulation
CAMK_CAMKL_BRSK_BRSK2_ST	P49815	TSC2	Q8IWQ3	BRSK2	S1002	S1002F	1002	Missense	central	0	yes	4.017	0.000	EPSD	ICGC;COSMIC	3.184	Loss
CAMK_CAMKL_BRSK_BRSK2_ST	P49815	TSC2	Q8IWQ3	BRSK2	S1002	S1002Y	1002	Missense	central	0	yes	4.017	0.000	EPSD	ICGC;COSMIC	3.184	Loss
CAMK_CAMKL_BRSK_BRSK2_ST	P49815	TSC2	Q8IWQ3	BRSK2	S1338	S1336L	1336	Missense	proximal	-2	no	4.897	4.914	EPSD	ICGC;COSMIC	3.184	Up-regulation
CAMK_CAMKL_BRSK_BRSK2_ST	P49815	TSC2	Q8IWQ3	BRSK2	S1341	S1336L	1336	Missense	distal	-5	no	4.517	4.511	EPSD	ICGC;COSMIC	3.184	Down-regulation
CAMK_CAMKL_BRSK_BRSK2_ST	P49815	TSC2	Q8IWQ3	BRSK2	S1383	S1388L	1388	Missense	distal	5	no	3.458	3.655	EPSD	ICGC;COSMIC	3.184	Up-regulation
CAMK_CAMKL_BRSK_BRSK2_ST	P49815	TSC2	Q8IWQ3	BRSK2	S1387	S1388L	1388	Missense	proximal	1	no	9.939	9.793	PhosphoSitePlus	ICGC;COSMIC	3.184	Down-regulation
Atypical_PIKK_DNAPK_PRKDC_ST	P78527	PRKDC	P78527	PRKDC	T398	K393N	393	Missense	distal	-5	no	11.570	11.449	EPSD	ICGC;COSMIC	8.283	Down-regulation
Atypical_PIKK_DNAPK_PRKDC_ST	P78527	PRKDC	P78527	PRKDC	T398	Q399K	399	Missense	proximal	1	no	11.570	0.365	EPSD	ICGC	8.283	Loss
Atypical_PIKK_DNAPK_PRKDC_ST	P78527	PRKDC	P78527	PRKDC	S505	G512E	512	Missense	distal	7	no	7.580	8.307	EPSD	ICGC;COSMIC	8.283	Gain
Atypical_PIKK_DNAPK_PRKDC_ST	P78527	PRKDC	P78527	PRKDC	S694	Y701F	701	Missense	distal	7	no	11.583	11.336	EPSD	ICGC;COSMIC	8.283	Down-regulation
Atypical_PIKK_DNAPK_PRKDC_ST	P78527	PRKDC	P78527	PRKDC	S882	A885T	885	Missense	distal	3	no	8.862	8.607	EPSD	ICGC;COSMIC	8.283	Down-regulation
Atypical_PIKK_DNAPK_PRKDC_ST	P78527	PRKDC	P78527	PRKDC	S882	M880I	880	Missense	proximal	-2	no	8.862	8.983	EPSD	ICGC;COSMIC	8.283	Up-regulation
Atypical_PIKK_DNAPK_PRKDC_ST	P78527	PRKDC	P78527	PRKDC	S882	W886R	886	Missense	distal	4	no	8.862	8.886	EPSD	ICGC;COSMIC	8.283	Up-regulation
Atypical_PIKK_DNAPK_PRKDC_ST	P78527	PRKDC	P78527	PRKDC	S882	D877Y	877	Missense	distal	-5	no	8.862	8.680	EPSD	ICGC	8.283	Down-regulation
Atypical_PIKK_DNAPK_PRKDC_ST	P78527	PRKDC	P78527	PRKDC	S1058	V1054A	1054	Missense	distal	-4	no	7.972	8.724	EPSD	ICGC;COSMIC	8.283	Gain
Atypical_PIKK_DNAPK_PRKDC_ST	P78527	PRKDC	P78527	PRKDC	T1793	R1787S	1787	Missense	distal	-6	no	8.197	8.700	EPSD	ICGC	8.283	Gain
Atypical_PIKK_DNAPK_PRKDC_ST	P14859	POU2F1	P78527	PRKDC	T21	D27N	27	Missense	distal	6	no	12.609	12.605	EPSD	ICGC;COSMIC	8.283	Down-regulation
Atypical_PIKK_DNAPK_PRKDC_ST	P14859	POU2F1	P78527	PRKDC	T21	D27G	27	Missense	distal	6	no	12.609	12.590	EPSD	ICGC	8.283	Down-regulation
Atypical_PIKK_DNAPK_PRKDC_ST	P14859	POU2F1	P78527	PRKDC	S78	S78L	78	Missense	central	0	yes	9.660	0.000	EPSD;PhosphoSitePlus	ICGC;COSMIC	8.283	Loss
Atypical_PIKK_DNAPK_PRKDC_ST	P14859	POU2F1	P78527	PRKDC	S78	S85I	85	Missense	distal	7	no	9.660	7.266	EPSD;PhosphoSitePlus	ICGC	8.283	Loss
Atypical_PIKK_DNAPK_PRKDC_ST	P14859	POU2F1	P78527	PRKDC	S78	Q71H	71	Missense	distal	-7	no	9.660	9.663	EPSD;PhosphoSitePlus	ICGC;COSMIC	8.283	Up-regulation
Atypical_PIKK_DNAPK_PRKDC_ST	P14859	POU2F1	P78527	PRKDC	S81	S78L	78	Missense	distal	-3	no	15.888	15.826	EPSD;PhosphoSitePlus	ICGC;COSMIC	8.283	Down-regulation
Atypical_PIKK_DNAPK_PRKDC_ST	P14859	POU2F1	P78527	PRKDC	S81	S85I	85	Missense	distal	4	no	15.888	15.815	EPSD;PhosphoSitePlus	ICGC	8.283	Down-regulation
Atypical_PIKK_DNAPK_PRKDC_ST	P14859	POU2F1	P78527	PRKDC	S81	Q86H	86	Missense	distal	5	no	15.888	15.718	EPSD;PhosphoSitePlus	ICGC	8.283	Down-regulation
Atypical_PIKK_DNAPK_PRKDC_ST	P14859	POU2F1	P78527	PRKDC	S85	S78L	78	Missense	distal	-7	no	15.039	14.573	EPSD;PhosphoSitePlus	ICGC;COSMIC	8.283	Down-regulation
Atypical_PIKK_DNAPK_PRKDC_ST	P14859	POU2F1	P78527	PRKDC	S85	S85I	85	Missense	central	0	yes	15.039	0.000	EPSD;PhosphoSitePlus	ICGC	8.283	Loss
Atypical_PIKK_DNAPK_PRKDC_ST	P14859	POU2F1	P78527	PRKDC	S85	Q90H	90	Missense	distal	5	no	15.039	14.870	EPSD;PhosphoSitePlus	ICGC	8.283	Down-regulation
Atypical_PIKK_DNAPK_PRKDC_ST	P14859	POU2F1	P78527	PRKDC	S85	Q86H	86	Missense	proximal	1	no	15.039	4.704	EPSD;PhosphoSitePlus	ICGC	8.283	Loss
Atypical_PIKK_DNAPK_PRKDC_ST	P14859	POU2F1	P78527	PRKDC	S88	S85I	85	Missense	distal	-3	no	14.542	14.035	EPSD;PhosphoSitePlus	ICGC	8.283	Down-regulation
Atypical_PIKK_DNAPK_PRKDC_ST	P14859	POU2F1	P78527	PRKDC	S88	Q90H	90	Missense	proximal	2	no	14.542	14.085	EPSD;PhosphoSitePlus	ICGC	8.283	Down-regulation
Atypical_PIKK_DNAPK_PRKDC_ST	P14859	POU2F1	P78527	PRKDC	S88	Q86H	86	Missense	proximal	-2	no	14.542	14.659	EPSD;PhosphoSitePlus	ICGC	8.283	Up-regulation
Atypical_PIKK_DNAPK_PRKDC_ST	P14859	POU2F1	P78527	PRKDC	S92	S85I	85	Missense	distal	-7	no	9.504	7.948	PhosphoSitePlus;EPSD	ICGC	8.283	Loss
Atypical_PIKK_DNAPK_PRKDC_ST	P14859	POU2F1	P78527	PRKDC	S92	Q90H	90	Missense	proximal	-2	no	9.504	9.622	PhosphoSitePlus;EPSD	ICGC	8.283	Up-regulation
Atypical_PIKK_DNAPK_PRKDC_ST	P14859	POU2F1	P78527	PRKDC	S92	Q86H	86	Missense	distal	-6	no	9.504	9.256	PhosphoSitePlus;EPSD	ICGC	8.283	Down-regulation
Atypical_PIKK_DNAPK_PRKDC_ST	P14859	POU2F1	P78527	PRKDC	S92	P98L	98	Missense	distal	6	no	9.504	9.493	PhosphoSitePlus;EPSD	ICGC	8.283	Down-regulation
Atypical_PIKK_DNAPK_PRKDC_ST	P14859	POU2F1	P78527	PRKDC	T100	P98L	98	Missense	proximal	-2	no	12.846	12.844	EPSD;PhosphoSitePlus	ICGC	8.283	Down-regulation
Atypical_PIKK_DNAPK_PRKDC_ST	P14859	POU2F1	P78527	PRKDC	S141	V137A	137	Missense	distal	-4	no	11.031	11.783	EPSD;PhosphoSitePlus	ICGC;COSMIC	8.283	Up-regulation
Atypical_PIKK_DNAPK_PRKDC_ST	P14859	POU2F1	P78527	PRKDC	S141	H140Q	140	Missense	proximal	-1	no	11.031	11.511	EPSD;PhosphoSitePlus	ICGC;COSMIC	8.283	Up-regulation
Atypical_PIKK_DNAPK_PRKDC_ST	P14859	POU2F1	P78527	PRKDC	S141	S147G	147	Missense	distal	6	no	11.031	11.022	EPSD;PhosphoSitePlus	ICGC	8.283	Down-regulation
Atypical_PIKK_DNAPK_PRKDC_ST	P14859	POU2F1	P78527	PRKDC	S143	V137A	137	Missense	distal	-6	no	13.593	14.349	EPSD;PhosphoSitePlus	ICGC;COSMIC	8.283	Up-regulation
Atypical_PIKK_DNAPK_PRKDC_ST	P14859	POU2F1	P78527	PRKDC	S143	H140Q	140	Missense	distal	-3	no	13.593	13.722	EPSD;PhosphoSitePlus	ICGC;COSMIC	8.283	Up-regulation
Atypical_PIKK_DNAPK_PRKDC_ST	P14859	POU2F1	P78527	PRKDC	S143	S147G	147	Missense	distal	4	no	13.593	13.586	EPSD;PhosphoSitePlus	ICGC	8.283	Down-regulation
Atypical_PIKK_DNAPK_PRKDC_ST	P14859	POU2F1	P78527	PRKDC	S147	H140Q	140	Missense	distal	-7	no	10.002	9.999	EPSD;PhosphoSitePlus	ICGC;COSMIC	8.283	Down-regulation
Atypical_PIKK_DNAPK_PRKDC_ST	P14859	POU2F1	P78527	PRKDC	S147	S147G	147	Missense	central	0	yes	10.002	0.000	EPSD;PhosphoSitePlus	ICGC	8.283	Loss
Atypical_PIKK_DNAPK_PRKDC_ST	P14859	POU2F1	P78527	PRKDC	T162	A155T	155	Missense	distal	-7	no	10.276	10.008	EPSD;PhosphoSitePlus	ICGC;COSMIC	8.283	Down-regulation
Atypical_PIKK_DNAPK_PRKDC_ST	P14859	POU2F1	P78527	PRKDC	T162	A155G	155	Missense	distal	-7	no	10.276	9.785	EPSD;PhosphoSitePlus	ICGC;COSMIC	8.283	Down-regulation
Atypical_PIKK_DNAPK_PRKDC_ST	P14859	POU2F1	P78527	PRKDC	T162	A158D	158	Missense	distal	-4	no	10.276	10.292	EPSD;PhosphoSitePlus	ICGC	8.283	Up-regulation
Atypical_PIKK_DNAPK_PRKDC_ST	P14859	POU2F1	P78527	PRKDC	T226	T226M	226	Missense	central	0	yes	12.076	0.000	EPSD;PhosphoSitePlus	ICGC	8.283	Loss
Atypical_PIKK_DNAPK_PRKDC_ST	P14859	POU2F1	P78527	PRKDC	T226	L228R	228	Missense	proximal	2	no	12.076	11.989	EPSD;PhosphoSitePlus	ICGC	8.283	Down-regulation
Atypical_PIKK_DNAPK_PRKDC_ST	P14859	POU2F1	P78527	PRKDC	T226	Q220P	220	Missense	distal	-6	no	12.076	11.606	EPSD;PhosphoSitePlus	ICGC	8.283	Down-regulation
Atypical_PIKK_DNAPK_PRKDC_ST	P14859	POU2F1	P78527	PRKDC	S232	T226M	226	Missense	distal	-6	no	13.566	13.433	EPSD;PhosphoSitePlus	ICGC	8.283	Down-regulation
Atypical_PIKK_DNAPK_PRKDC_ST	P14859	POU2F1	P78527	PRKDC	S232	Q238H	238	Missense	distal	6	no	13.566	13.556	EPSD;PhosphoSitePlus	ICGC	8.283	Down-regulation
Atypical_PIKK_DNAPK_PRKDC_ST	P14859	POU2F1	P78527	PRKDC	S232	L228R	228	Missense	distal	-4	no	13.566	13.415	EPSD;PhosphoSitePlus	ICGC	8.283	Down-regulation
Atypical_PIKK_DNAPK_PRKDC_ST	P14859	POU2F1	P78527	PRKDC	S232	S239L	239	Missense	distal	7	no	13.566	12.811	EPSD;PhosphoSitePlus	ICGC	8.283	Down-regulation
Atypical_PIKK_DNAPK_PRKDC_ST	P14859	POU2F1	P78527	PRKDC	T270	R273Q	273	Missense	distal	3	no	8.015	8.630	EPSD	ICGC;COSMIC	8.283	Gain
Atypical_PIKK_DNAPK_PRKDC_ST	P14859	POU2F1	P78527	PRKDC	T276	D275Y	275	Missense	proximal	-1	no	8.766	8.354	EPSD	ICGC	8.283	Down-regulation
Atypical_PIKK_DNAPK_PRKDC_ST	P14859	POU2F1	P78527	PRKDC	T276	R273Q	273	Missense	distal	-3	no	8.766	9.291	EPSD	ICGC;COSMIC	8.283	Up-regulation
Atypical_PIKK_DNAPK_PRKDC_ST	P14859	POU2F1	P78527	PRKDC	S322	R328Q	328	Missense	distal	6	no	11.405	11.441	EPSD	ICGC;COSMIC;GDSC;CCLE	8.283	Up-regulation
Atypical_PIKK_DNAPK_PRKDC_ST	P14859	POU2F1	P78527	PRKDC	S322	S322N	322	Missense	central	0	yes	11.405	0.000	EPSD	ICGC;COSMIC	8.283	Loss
Atypical_PIKK_DNAPK_PRKDC_ST	P14859	POU2F1	P78527	PRKDC	S322	R328L	328	Missense	distal	6	no	11.405	11.423	EPSD	ICGC;COSMIC	8.283	Up-regulation
Atypical_PIKK_DNAPK_PRKDC_ST	P14859	POU2F1	P78527	PRKDC	S322	S322I	322	Missense	central	0	yes	11.405	0.000	EPSD	ICGC	8.283	Loss
Atypical_PIKK_DNAPK_PRKDC_ST	P14859	POU2F1	P78527	PRKDC	S322	D320Y	320	Missense	proximal	-2	no	11.405	11.401	EPSD	ICGC	8.283	Down-regulation
Atypical_PIKK_DNAPK_PRKDC_ST	P14859	POU2F1	P78527	PRKDC	S322	G318E	318	Missense	distal	-4	no	11.405	11.809	EPSD	ICGC;COSMIC;GDSC	8.283	Up-regulation
Atypical_PIKK_DNAPK_PRKDC_ST	P14859	POU2F1	P78527	PRKDC	S358	S360L	360	Missense	proximal	2	no	9.180	7.991	EPSD	ICGC;COSMIC;GDSC	8.283	Loss
Atypical_PIKK_DNAPK_PRKDC_ST	P14859	POU2F1	P78527	PRKDC	S358	D352N	352	Missense	distal	-6	no	9.180	9.236	EPSD	ICGC;COSMIC	8.283	Up-regulation
Atypical_PIKK_DNAPK_PRKDC_ST	P14859	POU2F1	P78527	PRKDC	S361	S360L	360	Missense	proximal	-1	no	9.604	9.643	EPSD	ICGC;COSMIC;GDSC	8.283	Up-regulation
Atypical_PIKK_DNAPK_PRKDC_ST	P14859	POU2F1	P78527	PRKDC	S364	A367S	367	Missense	distal	3	no	9.327	9.392	EPSD	ICGC	8.283	Up-regulation
Atypical_PIKK_DNAPK_PRKDC_ST	P14859	POU2F1	P78527	PRKDC	S364	S360L	360	Missense	distal	-4	no	9.327	8.882	EPSD	ICGC;COSMIC;GDSC	8.283	Down-regulation
Atypical_PIKK_DNAPK_PRKDC_ST	P14859	POU2F1	P78527	PRKDC	S370	A367S	367	Missense	distal	-3	no	9.575	9.639	EPSD	ICGC	8.283	Up-regulation
Atypical_PIKK_DNAPK_PRKDC_ST	P35637	FUS	P78527	PRKDC	T7	D5Y	5	Missense	proximal	-2	no	13.626	13.622	EPSD;PhosphoSitePlus	ICGC;COSMIC	8.283	Down-regulation
Atypical_PIKK_DNAPK_PRKDC_ST	P35637	FUS	P78527	PRKDC	T11	D5Y	5	Missense	distal	-6	no	13.935	13.651	EPSD;PhosphoSitePlus	ICGC;COSMIC	8.283	Down-regulation
Atypical_PIKK_DNAPK_PRKDC_ST	P35637	FUS	P78527	PRKDC	T11	P18T	18	Missense	distal	7	no	13.935	13.214	EPSD;PhosphoSitePlus	ICGC;COSMIC	8.283	Down-regulation
Atypical_PIKK_DNAPK_PRKDC_ST	P35637	FUS	P78527	PRKDC	T19	P18T	18	Missense	proximal	-1	no	14.852	14.027	PhosphoSitePlus;EPSD	ICGC;COSMIC	8.283	Down-regulation
Atypical_PIKK_DNAPK_PRKDC_ST	P35637	FUS	P78527	PRKDC	T19	G24D	24	Missense	distal	5	no	14.852	15.042	PhosphoSitePlus;EPSD	ICGC	8.283	Up-regulation
Atypical_PIKK_DNAPK_PRKDC_ST	P35637	FUS	P78527	PRKDC	T19	P21S	21	Missense	proximal	2	no	14.852	15.082	PhosphoSitePlus;EPSD	ICGC;COSMIC	8.283	Up-regulation
Atypical_PIKK_DNAPK_PRKDC_ST	P35637	FUS	P78527	PRKDC	S26	G24D	24	Missense	proximal	-2	no	16.572	16.455	EPSD;PhosphoSitePlus	ICGC	8.283	Down-regulation
Atypical_PIKK_DNAPK_PRKDC_ST	P35637	FUS	P78527	PRKDC	S26	P21S	21	Missense	distal	-5	no	16.572	16.943	EPSD;PhosphoSitePlus	ICGC;COSMIC	8.283	Up-regulation
Atypical_PIKK_DNAPK_PRKDC_ST	P35637	FUS	P78527	PRKDC	S30	Q35H	35	Missense	distal	5	no	12.400	12.231	EPSD;PhosphoSitePlus	ICGC	8.283	Down-regulation
Atypical_PIKK_DNAPK_PRKDC_ST	P35637	FUS	P78527	PRKDC	S30	G24D	24	Missense	distal	-6	no	12.400	12.585	EPSD;PhosphoSitePlus	ICGC	8.283	Up-regulation
Atypical_PIKK_DNAPK_PRKDC_ST	P35637	FUS	P78527	PRKDC	S42	Q35H	35	Missense	distal	-7	no	13.722	13.725	EPSD;PhosphoSitePlus	ICGC	8.283	Up-regulation
Atypical_PIKK_DNAPK_PRKDC_ST	P35637	FUS	P78527	PRKDC	S42	G40C	40	Missense	proximal	-2	no	13.722	13.806	EPSD;PhosphoSitePlus	ICGC	8.283	Up-regulation
Atypical_PIKK_DNAPK_PRKDC_ST	P35637	FUS	P78527	PRKDC	S54	G59C	59	Missense	distal	5	no	11.624	11.540	EPSD;PhosphoSitePlus	ICGC	8.283	Down-regulation
Atypical_PIKK_DNAPK_PRKDC_ST	P35637	FUS	P78527	PRKDC	S61	G59C	59	Missense	proximal	-2	no	13.316	13.400	EPSD;PhosphoSitePlus	ICGC	8.283	Up-regulation
Atypical_PIKK_DNAPK_PRKDC_ST	P35637	FUS	P78527	PRKDC	S84	S86T	86	Missense	proximal	2	no	14.024	13.040	EPSD;PhosphoSitePlus	ICGC;COSMIC	8.283	Down-regulation
Atypical_PIKK_DNAPK_PRKDC_ST	P35637	FUS	P78527	PRKDC	S84	Y81C	81	Missense	distal	-3	no	14.024	13.549	EPSD;PhosphoSitePlus	ICGC;COSMIC	8.283	Down-regulation
Atypical_PIKK_DNAPK_PRKDC_ST	P35637	FUS	P78527	PRKDC	S87	S86T	86	Missense	proximal	-1	no	14.114	13.629	EPSD;PhosphoSitePlus	ICGC;COSMIC	8.283	Down-regulation
Atypical_PIKK_DNAPK_PRKDC_ST	P35637	FUS	P78527	PRKDC	S87	Y81C	81	Missense	distal	-6	no	14.114	13.651	EPSD;PhosphoSitePlus	ICGC;COSMIC	8.283	Down-regulation
Atypical_PIKK_DNAPK_PRKDC_ST	P35637	FUS	P78527	PRKDC	S112	S107N	107	Missense	distal	-5	no	9.169	9.015	EPSD;PhosphoSitePlus	ICGC;COSMIC	8.283	Down-regulation
Atypical_PIKK_DNAPK_PRKDC_ST	P35637	FUS	P78527	PRKDC	S117	S120R	120	Missense	distal	3	no	14.037	13.565	EPSD;PhosphoSitePlus	ICGC;COSMIC	8.283	Down-regulation
Atypical_PIKK_DNAPK_PRKDC_ST	P35637	FUS	P78527	PRKDC	S142	Q140P	140	Missense	proximal	-2	no	10.787	10.935	EPSD;PhosphoSitePlus	ICGC;COSMIC	8.283	Up-regulation
Atypical_PIKK_DNAPK_PRKDC_ST	P12956	XRCC6	P78527	PRKDC	S27	K31E	31	Missense	distal	4	no	10.764	10.776	PhosphoSitePlus;EPSD	ICGC;COSMIC	8.283	Up-regulation
Atypical_PIKK_DNAPK_PRKDC_ST	P12956	XRCC6	P78527	PRKDC	S27	L24I	24	Missense	distal	-3	no	10.764	10.319	PhosphoSitePlus;EPSD	ICGC;COSMIC	8.283	Down-regulation
Atypical_PIKK_DNAPK_PRKDC_ST	P12956	XRCC6	P78527	PRKDC	S33	K31E	31	Missense	proximal	-2	no	10.289	10.199	EPSD;PhosphoSitePlus	ICGC;COSMIC	8.283	Down-regulation
Atypical_PIKK_DNAPK_PRKDC_ST	P12956	XRCC6	P78527	PRKDC	S51	S45A	45	Missense	distal	-6	no	15.081	15.124	EPSD;PhosphoSitePlus	ICGC	8.283	Up-regulation
Atypical_PIKK_DNAPK_PRKDC_ST	P12956	XRCC6	P78527	PRKDC	T58	P59S	59	Missense	proximal	1	no	10.382	6.027	EPSD	ICGC	8.283	Loss
Atypical_PIKK_DNAPK_PRKDC_ST	P12956	XRCC6	P78527	PRKDC	T58	I64T	64	Missense	distal	6	no	10.382	10.413	EPSD	ICGC	8.283	Up-regulation
Atypical_PIKK_DNAPK_PRKDC_ST	P12956	XRCC6	P78527	PRKDC	T170	I166T	166	Missense	distal	-4	no	7.800	8.418	EPSD	ICGC;COSMIC	8.283	Gain
Atypical_PIKK_DNAPK_PRKDC_ST	Q96SD1	DCLRE1C	P78527	PRKDC	S3	F4L	4	Missense	proximal	1	no	7.997	10.313	EPSD	ICGC	8.283	Gain
Atypical_PIKK_DNAPK_PRKDC_ST	Q96SD1	DCLRE1C	P78527	PRKDC	S503	L504V	504	Missense	proximal	1	no	10.546	9.048	PhosphoSitePlus;EPSD	ICGC;COSMIC	8.283	Down-regulation
Atypical_PIKK_DNAPK_PRKDC_ST	Q96SD1	DCLRE1C	P78527	PRKDC	S538	E545Q	545	Missense	distal	7	no	13.949	14.045	EPSD;PhosphoSitePlus	ICGC;COSMIC	8.283	Up-regulation
Atypical_PIKK_DNAPK_PRKDC_ST	Q96SD1	DCLRE1C	P78527	PRKDC	S548	E545Q	545	Missense	distal	-3	no	10.820	10.970	EPSD;PhosphoSitePlus	ICGC;COSMIC	8.283	Up-regulation
Atypical_PIKK_DNAPK_PRKDC_ST	P23508	MCC	P78527	PRKDC	S118	N125Y	125	Missense	distal	7	no	14.462	14.564	EPSD;PhosphoSitePlus	ICGC;COSMIC	8.283	Up-regulation
Atypical_PIKK_DNAPK_PRKDC_ST	P23508	MCC	P78527	PRKDC	S118	E123D	123	Missense	distal	5	no	14.462	14.430	EPSD;PhosphoSitePlus	ICGC;COSMIC	8.283	Down-regulation
Atypical_PIKK_DNAPK_PRKDC_ST	P23508	MCC	P78527	PRKDC	S118	S115L	115	Missense	distal	-3	no	14.462	14.400	EPSD;PhosphoSitePlus	ICGC;COSMIC	8.283	Down-regulation
Atypical_PIKK_DNAPK_PRKDC_ST	P23508	MCC	P78527	PRKDC	S118	E116A	116	Missense	proximal	-2	no	14.462	14.495	EPSD;PhosphoSitePlus	ICGC;COSMIC	8.283	Up-regulation
Atypical_PIKK_DNAPK_PRKDC_ST	P23508	MCC	P78527	PRKDC	S118	H122N	122	Missense	distal	4	no	14.462	14.499	EPSD;PhosphoSitePlus	ICGC	8.283	Up-regulation
Atypical_PIKK_DNAPK_PRKDC_ST	P23508	MCC	P78527	PRKDC	S118	Q119K	119	Missense	proximal	1	no	14.462	3.257	EPSD;PhosphoSitePlus	ICGC	8.283	Loss
Atypical_PIKK_DNAPK_PRKDC_ST	P23508	MCC	P78527	PRKDC	S120	N125Y	125	Missense	distal	5	no	12.008	12.044	PhosphoSitePlus;EPSD	ICGC;COSMIC	8.283	Up-regulation
Atypical_PIKK_DNAPK_PRKDC_ST	P23508	MCC	P78527	PRKDC	S120	E123D	123	Missense	distal	3	no	12.008	11.803	PhosphoSitePlus;EPSD	ICGC;COSMIC	8.283	Down-regulation
Atypical_PIKK_DNAPK_PRKDC_ST	P23508	MCC	P78527	PRKDC	S120	S115L	115	Missense	distal	-5	no	12.008	11.650	PhosphoSitePlus;EPSD	ICGC;COSMIC	8.283	Down-regulation
Atypical_PIKK_DNAPK_PRKDC_ST	P23508	MCC	P78527	PRKDC	S120	E116A	116	Missense	distal	-4	no	12.008	11.975	PhosphoSitePlus;EPSD	ICGC;COSMIC	8.283	Down-regulation
Atypical_PIKK_DNAPK_PRKDC_ST	P23508	MCC	P78527	PRKDC	S120	H122N	122	Missense	proximal	2	no	12.008	11.466	PhosphoSitePlus;EPSD	ICGC	8.283	Down-regulation
Atypical_PIKK_DNAPK_PRKDC_ST	P23508	MCC	P78527	PRKDC	S120	Q119K	119	Missense	proximal	-1	no	12.008	10.627	PhosphoSitePlus;EPSD	ICGC	8.283	Down-regulation
Atypical_PIKK_DNAPK_PRKDC_ST	P23508	MCC	P78527	PRKDC	S120	E126K	126	Missense	distal	6	no	12.008	11.977	PhosphoSitePlus;EPSD	ICGC;COSMIC	8.283	Down-regulation
Atypical_PIKK_DNAPK_PRKDC_ST	P23508	MCC	P78527	PRKDC	S128	R129Q	129	Missense	proximal	1	no	4.557	14.972	EPSD	ICGC;COSMIC	8.283	Gain
Atypical_PIKK_DNAPK_PRKDC_ST	P23508	MCC	P78527	PRKDC	S182	S179R	179	Missense	distal	-3	no	9.659	9.407	EPSD	ICGC	8.283	Down-regulation
Atypical_PIKK_DNAPK_PRKDC_ST	P23508	MCC	P78527	PRKDC	S182	E187D	187	Missense	distal	5	no	9.659	9.627	EPSD	ICGC;COSMIC	8.283	Down-regulation
Atypical_PIKK_DNAPK_PRKDC_ST	P23508	MCC	P78527	PRKDC	S182	D189Y	189	Missense	distal	7	no	9.659	9.095	EPSD	ICGC	8.283	Down-regulation
Atypical_PIKK_DNAPK_PRKDC_ST	P23508	MCC	P78527	PRKDC	S182	G175V	175	Missense	distal	-7	no	9.659	9.228	EPSD	ICGC;COSMIC	8.283	Down-regulation
Atypical_PIKK_DNAPK_PRKDC_ST	P23508	MCC	P78527	PRKDC	S184	K190R	190	Missense	distal	6	no	9.489	9.477	EPSD	ICGC;COSMIC	8.283	Down-regulation
Atypical_PIKK_DNAPK_PRKDC_ST	P23508	MCC	P78527	PRKDC	S184	S179R	179	Missense	distal	-5	no	9.489	9.017	EPSD	ICGC	8.283	Down-regulation
Atypical_PIKK_DNAPK_PRKDC_ST	P23508	MCC	P78527	PRKDC	S184	E187D	187	Missense	distal	3	no	9.489	9.283	EPSD	ICGC;COSMIC	8.283	Down-regulation
Atypical_PIKK_DNAPK_PRKDC_ST	P23508	MCC	P78527	PRKDC	S184	D189Y	189	Missense	distal	5	no	9.489	9.374	EPSD	ICGC	8.283	Down-regulation
Atypical_PIKK_DNAPK_PRKDC_ST	P23508	MCC	P78527	PRKDC	S244	E243D	243	Missense	proximal	-1	no	9.678	9.423	EPSD	ICGC;COSMIC	8.283	Down-regulation
Atypical_PIKK_DNAPK_PRKDC_ST	P23508	MCC	P78527	PRKDC	S244	M248I	248	Missense	distal	4	no	9.678	9.634	EPSD	ICGC;COSMIC	8.283	Down-regulation
Atypical_PIKK_DNAPK_PRKDC_ST	P23508	MCC	P78527	PRKDC	S412	K411R	411	Missense	proximal	-1	no	10.789	10.638	EPSD	ICGC;COSMIC	8.283	Down-regulation
Atypical_PIKK_DNAPK_PRKDC_ST	P23508	MCC	P78527	PRKDC	S485	A479V	479	Missense	distal	-6	no	8.603	7.847	EPSD	ICGC	8.283	Loss
Atypical_PIKK_DNAPK_PRKDC_ST	P23508	MCC	P78527	PRKDC	S485	D488G	488	Missense	distal	3	no	8.603	8.307	EPSD	ICGC;COSMIC	8.283	Down-regulation
Atypical_PIKK_DNAPK_PRKDC_ST	P23508	MCC	P78527	PRKDC	S485	S490L	490	Missense	distal	5	no	8.603	8.527	EPSD	ICGC;COSMIC	8.283	Down-regulation
Atypical_PIKK_DNAPK_PRKDC_ST	P23508	MCC	P78527	PRKDC	S485	P486S	486	Missense	proximal	1	no	8.603	4.248	EPSD	ICGC;COSMIC	8.283	Loss
Atypical_PIKK_DNAPK_PRKDC_ST	P23508	MCC	P78527	PRKDC	T496	Q497K	497	Missense	proximal	1	no	11.741	0.536	EPSD	ICGC;COSMIC	8.283	Loss
Atypical_PIKK_DNAPK_PRKDC_ST	P23508	MCC	P78527	PRKDC	T496	R501Q	501	Missense	distal	5	no	11.741	12.063	EPSD	ICGC;COSMIC	8.283	Up-regulation
Atypical_PIKK_DNAPK_PRKDC_ST	P23508	MCC	P78527	PRKDC	T496	S490L	490	Missense	distal	-6	no	11.741	11.496	EPSD	ICGC;COSMIC	8.283	Down-regulation
Atypical_PIKK_DNAPK_PRKDC_ST	P23508	MCC	P78527	PRKDC	T496	H503N	503	Missense	distal	7	no	11.741	11.159	EPSD	ICGC;COSMIC	8.283	Down-regulation
Atypical_PIKK_DNAPK_PRKDC_ST	P23508	MCC	P78527	PRKDC	S702	P703Q	703	Missense	proximal	1	no	7.474	11.955	EPSD	ICGC;COSMIC	8.283	Gain
Atypical_PIKK_DNAPK_PRKDC_ST	P23508	MCC	P78527	PRKDC	S706	R711K	711	Missense	distal	5	no	8.856	8.935	EPSD	ICGC	8.283	Up-regulation
Atypical_PIKK_DNAPK_PRKDC_ST	P23508	MCC	P78527	PRKDC	S706	P703Q	703	Missense	distal	-3	no	8.856	8.991	EPSD	ICGC;COSMIC	8.283	Up-regulation
Atypical_PIKK_DNAPK_PRKDC_ST	P23508	MCC	P78527	PRKDC	S792	K789N	789	Missense	distal	-3	no	12.834	13.112	EPSD	ICGC;COSMIC	8.283	Up-regulation
Atypical_PIKK_DNAPK_PRKDC_ST	Q14653	IRF3	P78527	PRKDC	S14	L9M	9	Missense	distal	-5	no	12.832	12.721	EPSD	ICGC;COSMIC	8.283	Down-regulation
Atypical_PIKK_DNAPK_PRKDC_ST	Q14653	IRF3	P78527	PRKDC	S123	Q119K	119	Missense	distal	-4	no	8.768	8.367	EPSD	ICGC	8.283	Down-regulation
Atypical_PIKK_DNAPK_PRKDC_ST	Q13426	XRCC4	P78527	PRKDC	S260	S260N	260	Missense	central	0	yes	10.057	0.000	EPSD;PhosphoSitePlus	ICGC;COSMIC	8.283	Loss
Atypical_PIKK_DNAPK_PRKDC_ST	Q14191	WRN	P78527	PRKDC	S319	N314S	314	Missense	distal	-5	no	10.152	10.307	PhosphoSitePlus;EPSD	ICGC;COSMIC	8.283	Up-regulation
Atypical_PIKK_DNAPK_PRKDC_ST	Q14191	WRN	P78527	PRKDC	S319	D322Y	322	Missense	distal	3	no	10.152	9.962	PhosphoSitePlus;EPSD	ICGC;COSMIC	8.283	Down-regulation
Atypical_PIKK_DNAPK_PRKDC_ST	Q14191	WRN	P78527	PRKDC	S409	Q407P	407	Missense	proximal	-2	no	14.826	14.974	EPSD	ICGC	8.283	Up-regulation
Atypical_PIKK_DNAPK_PRKDC_ST	Q14191	WRN	P78527	PRKDC	S440	E445D	445	Missense	distal	5	no	10.299	10.268	EPSD;PhosphoSitePlus	ICGC;COSMIC	8.283	Down-regulation
Atypical_PIKK_DNAPK_PRKDC_ST	Q14191	WRN	P78527	PRKDC	S440	D441Y	441	Missense	proximal	1	no	10.299	12.760	EPSD;PhosphoSitePlus	ICGC	8.283	Up-regulation
Atypical_PIKK_DNAPK_PRKDC_ST	Q14191	WRN	P78527	PRKDC	S462	Y463H	463	Missense	proximal	1	no	9.037	2.697	EPSD	ICGC;COSMIC	8.283	Loss
Atypical_PIKK_DNAPK_PRKDC_ST	Q14191	WRN	P78527	PRKDC	S462	D460N	460	Missense	proximal	-2	no	9.037	9.060	EPSD	ICGC;COSMIC	8.283	Up-regulation
Atypical_PIKK_DNAPK_PRKDC_ST	Q14191	WRN	P78527	PRKDC	S462	T461M	461	Missense	proximal	-1	no	9.037	8.667	EPSD	ICGC;COSMIC	8.283	Down-regulation
Atypical_PIKK_DNAPK_PRKDC_ST	Q14191	WRN	P78527	PRKDC	S462	D460Y	460	Missense	proximal	-2	no	9.037	9.033	EPSD	ICGC;COSMIC	8.283	Down-regulation
Atypical_PIKK_DNAPK_PRKDC_ST	Q14191	WRN	P78527	PRKDC	S462	N459I	459	Missense	distal	-3	no	9.037	8.351	EPSD	ICGC;COSMIC	8.283	Down-regulation
Atypical_PIKK_DNAPK_PRKDC_ST	Q14191	WRN	P78527	PRKDC	S462	E469G	469	Missense	distal	7	no	9.037	8.310	EPSD	ICGC;COSMIC	8.283	Down-regulation
Atypical_PIKK_DNAPK_PRKDC_ST	Q14191	WRN	P78527	PRKDC	S467	E472D	472	Missense	distal	5	no	9.488	9.456	EPSD;PhosphoSitePlus	ICGC;COSMIC	8.283	Down-regulation
Atypical_PIKK_DNAPK_PRKDC_ST	Q14191	WRN	P78527	PRKDC	S467	Y463H	463	Missense	distal	-4	no	9.488	9.610	EPSD;PhosphoSitePlus	ICGC;COSMIC	8.283	Up-regulation
Atypical_PIKK_DNAPK_PRKDC_ST	Q14191	WRN	P78527	PRKDC	S467	D460N	460	Missense	distal	-7	no	9.488	9.338	EPSD;PhosphoSitePlus	ICGC;COSMIC	8.283	Down-regulation
Atypical_PIKK_DNAPK_PRKDC_ST	Q14191	WRN	P78527	PRKDC	S467	T461M	461	Missense	distal	-6	no	9.488	9.355	EPSD;PhosphoSitePlus	ICGC;COSMIC	8.283	Down-regulation
Atypical_PIKK_DNAPK_PRKDC_ST	Q14191	WRN	P78527	PRKDC	S467	D460Y	460	Missense	distal	-7	no	9.488	9.227	EPSD;PhosphoSitePlus	ICGC;COSMIC	8.283	Down-regulation
Atypical_PIKK_DNAPK_PRKDC_ST	Q14191	WRN	P78527	PRKDC	S467	E469G	469	Missense	proximal	2	no	9.488	8.079	EPSD;PhosphoSitePlus	ICGC;COSMIC	8.283	Loss
Atypical_PIKK_DNAPK_PRKDC_ST	Q14191	WRN	P78527	PRKDC	T777	L784P	784	Missense	distal	7	no	10.044	10.671	EPSD	ICGC;COSMIC	8.283	Up-regulation
Atypical_PIKK_DNAPK_PRKDC_ST	Q14191	WRN	P78527	PRKDC	S948	M949V	949	Missense	proximal	1	no	5.064	10.836	EPSD	ICGC;COSMIC	8.283	Gain
Atypical_PIKK_DNAPK_PRKDC_ST	Q14191	WRN	P78527	PRKDC	S1058	L1061I	1061	Missense	distal	3	no	12.557	11.998	EPSD	ICGC;COSMIC	8.283	Down-regulation
Atypical_PIKK_DNAPK_PRKDC_ST	Q14191	WRN	P78527	PRKDC	S1133	V1131L	1131	Missense	proximal	-2	no	11.445	11.357	EPSD	ICGC;COSMIC	8.283	Down-regulation
Atypical_PIKK_DNAPK_PRKDC_ST	P04637	TP53	P78527	PRKDC	S9	E11K	11	Missense	proximal	2	no	12.301	10.325	EPSD;PhosphoSitePlus	ICGC;COSMIC	8.283	Down-regulation
Atypical_PIKK_DNAPK_PRKDC_ST	P04637	TP53	P78527	PRKDC	S15	E11K	11	Missense	distal	-4	no	14.028	13.772	EPSD;PhosphoSitePlus	ICGC;COSMIC	8.283	Down-regulation
Atypical_PIKK_DNAPK_PRKDC_ST	P04637	TP53	P78527	PRKDC	S20	W23C	23	Missense	distal	3	no	8.830	9.078	EPSD;PhosphoSitePlus	ICGC;COSMIC	8.283	Up-regulation
Atypical_PIKK_DNAPK_PRKDC_ST	P04637	TP53	P78527	PRKDC	S33	P34L	34	Missense	proximal	1	no	9.126	9.065	EPSD	ICGC;COSMIC	8.283	Down-regulation
Atypical_PIKK_DNAPK_PRKDC_ST	P04637	TP53	P78527	PRKDC	S33	S33F	33	Missense	central	0	yes	9.126	0.000	EPSD	ICGC;COSMIC	8.283	Loss
Atypical_PIKK_DNAPK_PRKDC_ST	P04637	TP53	P78527	PRKDC	S33	N30I	30	Missense	distal	-3	no	9.126	8.440	EPSD	ICGC	8.283	Down-regulation
Atypical_PIKK_DNAPK_PRKDC_ST	P04637	TP53	P78527	PRKDC	S37	P34L	34	Missense	distal	-3	no	12.605	12.405	PhosphoSitePlus;EPSD	ICGC;COSMIC	8.283	Down-regulation
Atypical_PIKK_DNAPK_PRKDC_ST	P04637	TP53	P78527	PRKDC	S37	S33F	33	Missense	distal	-4	no	12.605	12.089	PhosphoSitePlus;EPSD	ICGC;COSMIC	8.283	Down-regulation
Atypical_PIKK_DNAPK_PRKDC_ST	P04637	TP53	P78527	PRKDC	S37	N30I	30	Missense	distal	-7	no	12.605	11.364	PhosphoSitePlus;EPSD	ICGC	8.283	Down-regulation
Atypical_PIKK_DNAPK_PRKDC_ST	P04637	TP53	P78527	PRKDC	S46	D48G	48	Missense	proximal	2	no	8.858	7.062	EPSD;PhosphoSitePlus	ICGC;COSMIC	8.283	Loss
Atypical_PIKK_DNAPK_PRKDC_ST	P04637	TP53	P78527	PRKDC	S46	Q52K	52	Missense	distal	6	no	8.858	8.833	EPSD;PhosphoSitePlus	ICGC	8.283	Down-regulation
Atypical_PIKK_DNAPK_PRKDC_ST	P04637	TP53	P78527	PRKDC	S99	Q100K	100	Missense	proximal	1	no	10.676	-0.529	EPSD	ICGC;COSMIC	8.283	Loss
Atypical_PIKK_DNAPK_PRKDC_ST	P04637	TP53	P78527	PRKDC	S99	P92T	92	Missense	distal	-7	no	10.676	11.007	EPSD	ICGC;COSMIC	8.283	Up-regulation
Atypical_PIKK_DNAPK_PRKDC_ST	P04637	TP53	P78527	PRKDC	S99	P92H	92	Missense	distal	-7	no	10.676	11.477	EPSD	ICGC;COSMIC	8.283	Up-regulation
Atypical_PIKK_DNAPK_PRKDC_ST	P04637	TP53	P78527	PRKDC	S99	G105A	105	Missense	distal	6	no	10.676	10.686	EPSD	ICGC;COSMIC	8.283	Up-regulation
Atypical_PIKK_DNAPK_PRKDC_ST	P04637	TP53	P78527	PRKDC	T125	C124G	124	Missense	proximal	-1	no	7.932	8.350	EPSD	ICGC;COSMIC	8.283	Gain
Atypical_PIKK_DNAPK_PRKDC_ST	P04637	TP53	P78527	PRKDC	T125	C124Y	124	Missense	proximal	-1	no	7.932	8.951	EPSD	ICGC;COSMIC	8.283	Gain
Atypical_PIKK_DNAPK_PRKDC_ST	P04637	TP53	P78527	PRKDC	S269	V272E	272	Missense	distal	3	no	7.664	8.493	EPSD	ICGC;COSMIC;CCLE	8.283	Gain
Atypical_PIKK_DNAPK_PRKDC_ST	Q9UGP5	POLL	P78527	PRKDC	S167	L166V	166	Missense	proximal	-1	no	8.825	7.885	EPSD	ICGC;COSMIC	8.283	Loss
Atypical_PIKK_DNAPK_PRKDC_ST	Q9UGP5	POLL	P78527	PRKDC	T204	G201V	201	Missense	distal	-3	no	11.288	11.199	PhosphoSitePlus	ICGC;COSMIC;GDSC;CCLE	8.283	Down-regulation
Atypical_PIKK_DNAPK_PRKDC_ST	Q9UGP5	POLL	P78527	PRKDC	T204	S199T	199	Missense	distal	-5	no	11.288	11.047	PhosphoSitePlus	ICGC;COSMIC	8.283	Down-regulation
Atypical_PIKK_DNAPK_PRKDC_ST	Q9UGP5	POLL	P78527	PRKDC	T398	Q404K	404	Missense	distal	6	no	9.494	9.469	EPSD	ICGC;COSMIC	8.283	Down-regulation
Atypical_PIKK_DNAPK_PRKDC_ST	Q9UGP5	POLL	P78527	PRKDC	T398	T398I	398	Missense	central	0	yes	9.494	0.000	EPSD	ICGC;COSMIC	8.283	Loss
Atypical_PIKK_DNAPK_PRKDC_ST	Q9UGP5	POLL	P78527	PRKDC	S526	S526N	526	Missense	central	0	yes	9.461	0.000	EPSD	ICGC;COSMIC	8.283	Loss
Atypical_PIKK_DNAPK_PRKDC_ST	Q9UGP5	POLL	P78527	PRKDC	S526	M525I	525	Missense	proximal	-1	no	9.461	8.949	EPSD	ICGC;COSMIC	8.283	Down-regulation
Atypical_PIKK_DNAPK_PRKDC_ST	P23025	XPA	P78527	PRKDC	S173	S173L	173	Missense	central	0	yes	11.286	0.000	EPSD;PhosphoSitePlus	ICGC;COSMIC	8.283	Loss
Atypical_PIKK_DNAPK_PRKDC_ST	P23025	XPA	P78527	PRKDC	S196	V193I	193	Missense	distal	-3	no	13.509	13.248	PhosphoSitePlus;EPSD	ICGC	8.283	Down-regulation
Atypical_PIKK_DNAPK_PRKDC_ST	P23025	XPA	P78527	PRKDC	S196	E198D	198	Missense	proximal	2	no	13.509	13.896	PhosphoSitePlus;EPSD	ICGC	8.283	Up-regulation
Atypical_PIKK_DNAPK_PRKDC_ST	P17936	IGFBP3	P78527	PRKDC	T7	R3Q	3	Missense	distal	-4	no	7.728	8.426	EPSD	ICGC	8.283	Gain
Atypical_PIKK_DNAPK_PRKDC_ST	P17936	IGFBP3	P78527	PRKDC	T14	L8I	8	Missense	distal	-6	no	8.456	7.474	EPSD	ICGC	8.283	Loss
Atypical_PIKK_DNAPK_PRKDC_ST	P17936	IGFBP3	P78527	PRKDC	T14	L16F	16	Missense	proximal	2	no	8.456	8.543	EPSD	ICGC	8.283	Up-regulation
Atypical_PIKK_DNAPK_PRKDC_ST	Q9H9Q4	NHEJ1	P78527	PRKDC	S55	D50E	50	Missense	distal	-5	no	10.966	11.150	EPSD;PhosphoSitePlus	ICGC	8.283	Up-regulation
Atypical_PIKK_DNAPK_PRKDC_ST	Q9H9Q4	NHEJ1	P78527	PRKDC	S55	Q48H	48	Missense	distal	-7	no	10.966	10.970	EPSD;PhosphoSitePlus	ICGC;COSMIC	8.283	Up-regulation
Atypical_PIKK_DNAPK_PRKDC_ST	Q9H9Q4	NHEJ1	P78527	PRKDC	S132	P138L	138	Missense	distal	6	no	10.403	10.392	EPSD;PhosphoSitePlus	ICGC	8.283	Down-regulation
Atypical_PIKK_DNAPK_PRKDC_ST	Q9H9Q4	NHEJ1	P78527	PRKDC	S132	R137S	137	Missense	distal	5	no	10.403	10.608	EPSD;PhosphoSitePlus	ICGC;COSMIC	8.283	Up-regulation
Atypical_PIKK_DNAPK_PRKDC_ST	Q9H9Q4	NHEJ1	P78527	PRKDC	S132	R137H	137	Missense	distal	5	no	10.403	10.555	EPSD;PhosphoSitePlus	ICGC;COSMIC	8.283	Up-regulation
Atypical_PIKK_DNAPK_PRKDC_ST	Q9H9Q4	NHEJ1	P78527	PRKDC	S132	Q133K	133	Missense	proximal	1	no	10.403	-0.802	EPSD;PhosphoSitePlus	ICGC;COSMIC	8.283	Loss
Atypical_PIKK_DNAPK_PRKDC_ST	Q9H9Q4	NHEJ1	P78527	PRKDC	T223	Q230K	230	Missense	distal	7	no	11.838	10.929	EPSD;PhosphoSitePlus	ICGC	8.283	Down-regulation
Atypical_PIKK_DNAPK_PRKDC_ST	Q9H9Q4	NHEJ1	P78527	PRKDC	S245	H239Y	239	Missense	distal	-6	no	9.742	9.491	EPSD;PhosphoSitePlus	ICGC;COSMIC	8.283	Down-regulation
Atypical_PIKK_DNAPK_PRKDC_ST	Q9H9Q4	NHEJ1	P78527	PRKDC	S245	Q247K	247	Missense	proximal	2	no	9.742	8.322	EPSD;PhosphoSitePlus	ICGC	8.283	Down-regulation
Atypical_PIKK_DNAPK_PRKDC_ST	Q9H9Q4	NHEJ1	P78527	PRKDC	S245	D250N	250	Missense	distal	5	no	9.742	9.592	EPSD;PhosphoSitePlus	ICGC;GDSC;CCLE	8.283	Down-regulation
Atypical_PIKK_DNAPK_PRKDC_ST	Q9H9Q4	NHEJ1	P78527	PRKDC	S251	Q247K	247	Missense	distal	-4	no	11.994	11.593	EPSD;PhosphoSitePlus	ICGC	8.283	Down-regulation
Atypical_PIKK_DNAPK_PRKDC_ST	Q9H9Q4	NHEJ1	P78527	PRKDC	S251	D250N	250	Missense	proximal	-1	no	11.994	11.252	EPSD;PhosphoSitePlus	ICGC;GDSC;CCLE	8.283	Down-regulation
Atypical_PIKK_DNAPK_PRKDC_ST	Q9H9Q4	NHEJ1	P78527	PRKDC	S263	P265T	265	Missense	proximal	2	no	10.763	10.009	EPSD;PhosphoSitePlus	ICGC;COSMIC	8.283	Down-regulation
Atypical_PIKK_DNAPK_PRKDC_ST	Q9H9Q4	NHEJ1	P78527	PRKDC	T266	P265T	265	Missense	proximal	-1	no	10.476	9.651	PhosphoSitePlus;EPSD	ICGC;COSMIC	8.283	Down-regulation
Atypical_PIKK_DNAPK_PRKDC_ST	P07900	HSP90AA1	P78527	PRKDC	T5	E3K	3	Missense	proximal	-2	no	13.034	13.124	EPSD;PhosphoSitePlus	ICGC	8.283	Up-regulation
Atypical_PIKK_DNAPK_PRKDC_ST	P07900	HSP90AA1	P78527	PRKDC	T7	E3K	3	Missense	distal	-4	no	15.903	15.646	PhosphoSitePlus;EPSD	ICGC	8.283	Down-regulation
Atypical_PIKK_DNAPK_PRKDC_ST	P07900	HSP90AA1	P78527	PRKDC	T19	F20L	20	Missense	proximal	1	no	6.837	9.154	EPSD	ICGC	8.283	Gain
Atypical_PIKK_DNAPK_PRKDC_ST	P07900	HSP90AA1	P78527	PRKDC	S164	S165L	165	Missense	proximal	1	no	6.182	10.476	EPSD	ICGC;COSMIC	8.283	Gain
Atypical_PIKK_DNAPK_PRKDC_ST	P07900	HSP90AA1	P78527	PRKDC	S211	V207A	207	Missense	distal	-4	no	7.719	8.471	EPSD	ICGC;COSMIC	8.283	Gain
Atypical_PIKK_DNAPK_PRKDC_ST	P07900	HSP90AA1	P78527	PRKDC	S252	K245E	245	Missense	distal	-7	no	9.472	9.726	EPSD	ICGC;COSMIC	8.283	Up-regulation
Atypical_PIKK_DNAPK_PRKDC_ST	P07900	HSP90AA1	P78527	PRKDC	S453	R456Q	456	Missense	distal	3	no	10.301	10.916	EPSD	ICGC;COSMIC	8.283	Up-regulation
Atypical_PIKK_DNAPK_PRKDC_ST	P07900	HSP90AA1	P78527	PRKDC	S677	H684R	684	Missense	distal	7	no	11.015	9.834	EPSD	ICGC;COSMIC	8.283	Down-regulation
Atypical_PIKK_DNAPK_PRKDC_ST	P13010	XRCC5	P78527	PRKDC	S145	S143C	143	Missense	proximal	-2	no	12.692	12.847	EPSD	ICGC;COSMIC	8.283	Up-regulation
Atypical_PIKK_DNAPK_PRKDC_ST	P13010	XRCC5	P78527	PRKDC	S577	V578I	578	Missense	proximal	1	no	8.799	1.883	EPSD;PhosphoSitePlus	ICGC;COSMIC;CCLE	8.283	Loss
Atypical_PIKK_DNAPK_PRKDC_ST	P13010	XRCC5	P78527	PRKDC	S577	Q571E	571	Missense	distal	-6	no	8.799	8.733	EPSD;PhosphoSitePlus	ICGC;COSMIC	8.283	Down-regulation
Atypical_PIKK_DNAPK_PRKDC_ST	P13010	XRCC5	P78527	PRKDC	S580	S585I	585	Missense	distal	5	no	9.864	9.522	PhosphoSitePlus;EPSD	ICGC	8.283	Down-regulation
Atypical_PIKK_DNAPK_PRKDC_ST	P13010	XRCC5	P78527	PRKDC	S580	V578I	578	Missense	proximal	-2	no	9.864	10.009	PhosphoSitePlus;EPSD	ICGC;COSMIC;CCLE	8.283	Up-regulation
Atypical_PIKK_DNAPK_PRKDC_ST	P13010	XRCC5	P78527	PRKDC	S712	A706S	706	Missense	distal	-6	no	8.864	8.821	EPSD	ICGC	8.283	Down-regulation
Atypical_PIKK_DNAPK_PRKDC_ST	P13010	XRCC5	P78527	PRKDC	S712	V718L	718	Missense	distal	6	no	8.864	8.876	EPSD	ICGC	8.283	Up-regulation
Atypical_PIKK_DNAPK_PRKDC_ST	P13010	XRCC5	P78527	PRKDC	S712	A716S	716	Missense	distal	4	no	8.864	8.845	EPSD	ICGC;COSMIC	8.283	Down-regulation
Atypical_PIKK_DNAPK_PRKDC_ST	P13010	XRCC5	P78527	PRKDC	T715	V718L	718	Missense	distal	3	no	8.413	8.619	EPSD;PhosphoSitePlus	ICGC	8.283	Up-regulation
Atypical_PIKK_DNAPK_PRKDC_ST	P13010	XRCC5	P78527	PRKDC	T715	A716S	716	Missense	proximal	1	no	8.413	4.882	EPSD;PhosphoSitePlus	ICGC;COSMIC	8.283	Loss
Atypical_PIKK_DNAPK_PRKDC_ST	P46527	CDKN1B	P78527	PRKDC	S10	N8K	8	Missense	proximal	-2	no	9.159	9.226	EPSD	ICGC;COSMIC	8.283	Up-regulation
Atypical_PIKK_DNAPK_PRKDC_ST	P46527	CDKN1B	P78527	PRKDC	S12	N8K	8	Missense	distal	-4	no	10.753	10.477	EPSD	ICGC;COSMIC	8.283	Down-regulation
Atypical_PIKK_DNAPK_PRKDC_ST	P46527	CDKN1B	P78527	PRKDC	S106	V109G	109	Missense	distal	3	no	12.199	12.527	EPSD	ICGC;COSMIC	8.283	Up-regulation
Atypical_PIKK_DNAPK_PRKDC_ST	P46527	CDKN1B	P78527	PRKDC	S106	C99W	99	Missense	distal	-7	no	12.199	11.885	EPSD	ICGC;COSMIC	8.283	Down-regulation
Atypical_PIKK_DNAPK_PRKDC_ST	P46527	CDKN1B	P78527	PRKDC	S106	P102T	102	Missense	distal	-4	no	12.199	11.954	EPSD	ICGC;COSMIC	8.283	Down-regulation
Atypical_PIKK_DNAPK_PRKDC_ST	P46527	CDKN1B	P78527	PRKDC	S110	V109G	109	Missense	proximal	-1	no	8.649	9.288	EPSD	ICGC;COSMIC	8.283	Up-regulation
Atypical_PIKK_DNAPK_PRKDC_ST	P46527	CDKN1B	P78527	PRKDC	S140	S138W	138	Missense	proximal	-2	no	14.217	14.445	PhosphoSitePlus	ICGC	8.283	Up-regulation
Atypical_PIKK_DNAPK_PRKDC_ST	P46527	CDKN1B	P78527	PRKDC	S178	V184M	184	Missense	distal	6	no	9.090	9.084	EPSD	ICGC;COSMIC	8.283	Down-regulation
Atypical_PIKK_DNAPK_PRKDC_ST	P46527	CDKN1B	P78527	PRKDC	S178	G182C	182	Missense	distal	4	no	9.090	9.053	EPSD	ICGC	8.283	Down-regulation
Atypical_PIKK_DNAPK_PRKDC_ST	P46527	CDKN1B	P78527	PRKDC	S178	G177V	177	Missense	proximal	-1	no	9.090	8.451	EPSD	ICGC	8.283	Down-regulation
Atypical_PIKK_DNAPK_PRKDC_ST	P46527	CDKN1B	P78527	PRKDC	S178	S178F	178	Missense	central	0	yes	9.090	0.000	EPSD	ICGC;COSMIC	8.283	Loss
Atypical_PIKK_DNAPK_PRKDC_ST	P46527	CDKN1B	P78527	PRKDC	T187	V184M	184	Missense	distal	-3	no	9.114	9.093	EPSD	ICGC;COSMIC	8.283	Down-regulation
Atypical_PIKK_DNAPK_PRKDC_ST	P46527	CDKN1B	P78527	PRKDC	T187	G192V	192	Missense	distal	5	no	9.114	9.074	EPSD	ICGC	8.283	Down-regulation
Atypical_PIKK_DNAPK_PRKDC_ST	P46527	CDKN1B	P78527	PRKDC	T187	G182C	182	Missense	distal	-5	no	9.114	8.958	EPSD	ICGC	8.283	Down-regulation
Atypical_PIKK_DNAPK_PRKDC_ST	P46527	CDKN1B	P78527	PRKDC	T187	P191H	191	Missense	distal	4	no	9.114	9.123	EPSD	ICGC;COSMIC	8.283	Up-regulation
Atypical_PIKK_DNAPK_PRKDC_ST	P19838	NFKB1	P78527	PRKDC	S20	L21F	21	Missense	proximal	1	no	8.943	6.627	PhosphoSitePlus	ICGC	8.283	Loss
Atypical_PIKK_DNAPK_PRKDC_ST	P19838	NFKB1	P78527	PRKDC	S80	S74I	74	Missense	distal	-6	no	8.663	7.436	EPSD	ICGC	8.283	Loss
Atypical_PIKK_DNAPK_PRKDC_ST	P19838	NFKB1	P78527	PRKDC	S80	K78N	78	Missense	proximal	-2	no	8.663	8.595	EPSD	ICGC;COSMIC	8.283	Down-regulation
Atypical_PIKK_DNAPK_PRKDC_ST	P19838	NFKB1	P78527	PRKDC	S80	P82H	82	Missense	proximal	2	no	8.663	8.513	EPSD	ICGC;COSMIC	8.283	Down-regulation
Atypical_PIKK_DNAPK_PRKDC_ST	P19838	NFKB1	P78527	PRKDC	S371	S371L	371	Missense	central	0	yes	8.314	0.000	EPSD	ICGC;COSMIC	8.283	Loss
Atypical_PIKK_DNAPK_PRKDC_ST	P19838	NFKB1	P78527	PRKDC	S371	G377S	377	Missense	distal	6	no	8.314	8.323	EPSD	ICGC;GDSC	8.283	Up-regulation
Atypical_PIKK_DNAPK_PRKDC_ST	P19838	NFKB1	P78527	PRKDC	S371	N369K	369	Missense	proximal	-2	no	8.314	8.382	EPSD	ICGC;COSMIC	8.283	Up-regulation
Atypical_PIKK_DNAPK_PRKDC_ST	P19838	NFKB1	P78527	PRKDC	S371	L366P	366	Missense	distal	-5	no	8.314	8.302	EPSD	ICGC;COSMIC	8.283	Down-regulation
Atypical_PIKK_DNAPK_PRKDC_ST	P19838	NFKB1	P78527	PRKDC	S371	P368S	368	Missense	distal	-3	no	8.314	8.176	EPSD	ICGC;COSMIC	8.283	Loss
Atypical_PIKK_DNAPK_PRKDC_ST	P19838	NFKB1	P78527	PRKDC	T413	G415V	415	Missense	proximal	2	no	8.807	7.924	EPSD	ICGC	8.283	Loss
Atypical_PIKK_DNAPK_PRKDC_ST	P19838	NFKB1	P78527	PRKDC	T413	P412S	412	Missense	proximal	-1	no	8.807	8.467	EPSD	ICGC;COSMIC	8.283	Down-regulation
Atypical_PIKK_DNAPK_PRKDC_ST	P19838	NFKB1	P78527	PRKDC	T413	P412H	412	Missense	proximal	-1	no	8.807	8.778	EPSD	ICGC;COSMIC	8.283	Down-regulation
Atypical_PIKK_DNAPK_PRKDC_ST	P19838	NFKB1	P78527	PRKDC	T413	H420N	420	Missense	distal	7	no	8.807	8.225	EPSD	ICGC;COSMIC	8.283	Loss
Atypical_PIKK_DNAPK_PRKDC_ST	P19838	NFKB1	P78527	PRKDC	T413	T413I	413	Missense	central	0	yes	8.807	0.000	EPSD	ICGC	8.283	Loss
Atypical_PIKK_DNAPK_PRKDC_ST	P19838	NFKB1	P78527	PRKDC	S899	S892F	892	Missense	distal	-7	no	12.719	12.174	EPSD	ICGC;COSMIC	8.283	Down-regulation
Atypical_PIKK_DNAPK_PRKDC_ST	P19838	NFKB1	P78527	PRKDC	S899	Q900E	900	Missense	proximal	1	no	12.719	4.984	EPSD	ICGC;COSMIC	8.283	Loss
Atypical_PIKK_DNAPK_PRKDC_ST	P19838	NFKB1	P78527	PRKDC	S899	S892Y	892	Missense	distal	-7	no	12.719	12.291	EPSD	ICGC;COSMIC	8.283	Down-regulation
Atypical_PIKK_DNAPK_PRKDC_ST	P19838	NFKB1	P78527	PRKDC	S899	S892P	892	Missense	distal	-7	no	12.719	12.069	EPSD	ICGC;COSMIC	8.283	Down-regulation
Atypical_PIKK_DNAPK_PRKDC_ST	P19838	NFKB1	P78527	PRKDC	S899	A901D	901	Missense	proximal	2	no	12.719	13.766	EPSD	ICGC;COSMIC	8.283	Up-regulation
Atypical_PIKK_DNAPK_PRKDC_ST	P19838	NFKB1	P78527	PRKDC	S899	P894L	894	Missense	distal	-5	no	12.719	12.731	EPSD	ICGC	8.283	Up-regulation
Atypical_PIKK_DNAPK_PRKDC_ST	P19838	NFKB1	P78527	PRKDC	S907	Q900E	900	Missense	distal	-7	no	9.433	9.331	EPSD	ICGC;COSMIC	8.283	Down-regulation
Atypical_PIKK_DNAPK_PRKDC_ST	P19838	NFKB1	P78527	PRKDC	S907	A901D	901	Missense	distal	-6	no	9.433	9.279	EPSD	ICGC;COSMIC	8.283	Down-regulation
Atypical_PIKK_DNAPK_PRKDC_ST	P19838	NFKB1	P78527	PRKDC	S907	S907L	907	Missense	central	0	yes	9.433	0.000	EPSD	ICGC;COSMIC	8.283	Loss
Atypical_PIKK_DNAPK_PRKDC_ST	P19838	NFKB1	P78527	PRKDC	S907	Q913H	913	Missense	distal	6	no	9.433	9.423	EPSD	ICGC;COSMIC	8.283	Down-regulation
Atypical_PIKK_DNAPK_PRKDC_ST	P19838	NFKB1	P78527	PRKDC	S907	P908H	908	Missense	proximal	1	no	9.433	3.579	EPSD	ICGC;COSMIC	8.283	Loss
Atypical_PIKK_DNAPK_PRKDC_ST	P19838	NFKB1	P78527	PRKDC	S947	L951V	951	Missense	distal	4	no	9.048	9.019	EPSD	ICGC;COSMIC	8.283	Down-regulation
Atypical_PIKK_DNAPK_PRKDC_ST	P19838	NFKB1	P78527	PRKDC	S947	A946V	946	Missense	proximal	-1	no	9.048	7.737	EPSD	ICGC	8.283	Loss
Atypical_PIKK_DNAPK_PRKDC_ST	P19838	NFKB1	P78527	PRKDC	S947	S944R	944	Missense	distal	-3	no	9.048	8.796	EPSD	ICGC	8.283	Down-regulation
Atypical_PIKK_DNAPK_PRKDC_ST	Q00839	HNRNPU	P78527	PRKDC	S382	K387R	387	Missense	distal	5	no	9.953	9.874	EPSD	ICGC;COSMIC	8.283	Down-regulation
Atypical_PIKK_DNAPK_PRKDC_ST	Q00839	HNRNPU	P78527	PRKDC	S382	K387N	387	Missense	distal	5	no	9.953	10.003	EPSD	ICGC	8.283	Up-regulation
Atypical_PIKK_DNAPK_PRKDC_ST	Q00839	HNRNPU	P78527	PRKDC	S382	E376K	376	Missense	distal	-6	no	9.953	9.743	EPSD	ICGC	8.283	Down-regulation
Atypical_PIKK_DNAPK_PRKDC_ST	Q00839	HNRNPU	P78527	PRKDC	T554	Q557H	557	Missense	distal	3	no	9.919	9.611	EPSD	ICGC;COSMIC	8.283	Down-regulation
Atypical_PIKK_DNAPK_PRKDC_ST	Q00839	HNRNPU	P78527	PRKDC	S817	P815T	815	Missense	proximal	-2	no	13.216	13.261	EPSD	ICGC;COSMIC	8.283	Up-regulation
Atypical_PIKK_DNAPK_PRKDC_ST	Q00839	HNRNPU	P78527	PRKDC	S817	Q822K	822	Missense	distal	5	no	13.216	12.973	EPSD	ICGC	8.283	Down-regulation
Atypical_PIKK_DNAPK_PRKDC_ST	Q00839	HNRNPU	P78527	PRKDC	S817	H819R	819	Missense	proximal	2	no	13.216	12.320	EPSD	ICGC;COSMIC	8.283	Down-regulation
Atypical_PIKK_DNAPK_PRKDC_ST	P15927	RPA2	P78527	PRKDC	S13	A17E	17	Missense	distal	4	no	9.212	9.216	EPSD	ICGC	8.283	Up-regulation
Atypical_PIKK_DNAPK_PRKDC_ST	P15927	RPA2	P78527	PRKDC	T21	A17E	17	Missense	distal	-4	no	13.040	13.073	EPSD;PhosphoSitePlus	ICGC	8.283	Up-regulation
Atypical_PIKK_DNAPK_PRKDC_ST	P15927	RPA2	P78527	PRKDC	S23	A17E	17	Missense	distal	-6	no	12.207	12.203	EPSD;PhosphoSitePlus	ICGC	8.283	Down-regulation
Atypical_PIKK_DNAPK_PRKDC_ST	P15927	RPA2	P78527	PRKDC	T110	D111Y	111	Missense	proximal	1	no	6.336	8.797	EPSD	ICGC;COSMIC	8.283	Gain
Atypical_PIKK_DNAPK_PRKDC_ST	P24928	POLR2A	P78527	PRKDC	S8	S8L	8	Missense	central	0	yes	8.663	0.000	EPSD	ICGC;COSMIC	8.283	Loss
Atypical_PIKK_DNAPK_PRKDC_ST	P24928	POLR2A	P78527	PRKDC	T732	R734W	734	Missense	proximal	2	no	8.341	7.592	EPSD	ICGC	8.283	Loss
Atypical_PIKK_DNAPK_PRKDC_ST	P24928	POLR2A	P78527	PRKDC	T732	T736M	736	Missense	distal	4	no	8.341	8.352	EPSD	ICGC	8.283	Up-regulation
Atypical_PIKK_DNAPK_PRKDC_ST	P24928	POLR2A	P78527	PRKDC	T732	F737C	737	Missense	distal	5	no	8.341	8.186	EPSD	ICGC	8.283	Loss
Atypical_PIKK_DNAPK_PRKDC_ST	P24928	POLR2A	P78527	PRKDC	T1568	G1570D	1570	Missense	proximal	2	no	7.576	9.372	EPSD	ICGC	8.283	Gain
Atypical_PIKK_DNAPK_PRKDC_ST	P24928	POLR2A	P78527	PRKDC	S1574	G1570D	1570	Missense	distal	-4	no	9.448	9.835	EPSD	ICGC	8.283	Up-regulation
Atypical_PIKK_DNAPK_PRKDC_ST	P24928	POLR2A	P78527	PRKDC	S1619	T1625P	1625	Missense	distal	6	no	8.764	8.777	EPSD	ICGC	8.283	Up-regulation
Atypical_PIKK_DNAPK_PRKDC_ST	P24928	POLR2A	P78527	PRKDC	S1621	T1625P	1625	Missense	distal	4	no	9.489	9.504	EPSD;PhosphoSitePlus	ICGC	8.283	Up-regulation
Atypical_PIKK_DNAPK_PRKDC_ST	P24928	POLR2A	P78527	PRKDC	S1626	T1625P	1625	Missense	proximal	-1	no	9.182	10.007	EPSD	ICGC	8.283	Up-regulation
Atypical_PIKK_DNAPK_PRKDC_ST	P24928	POLR2A	P78527	PRKDC	S1647	S1644L	1644	Missense	distal	-3	no	8.446	8.384	EPSD	ICGC	8.283	Down-regulation
Atypical_PIKK_DNAPK_PRKDC_ST	P24928	POLR2A	P78527	PRKDC	S1649	S1644L	1644	Missense	distal	-5	no	10.108	9.749	EPSD	ICGC	8.283	Down-regulation
Atypical_PIKK_DNAPK_PRKDC_ST	P24928	POLR2A	P78527	PRKDC	S1661	S1665P	1665	Missense	distal	4	no	8.465	8.439	EPSD	ICGC	8.283	Down-regulation
Atypical_PIKK_DNAPK_PRKDC_ST	P24928	POLR2A	P78527	PRKDC	S1663	S1665P	1665	Missense	proximal	2	no	9.778	9.547	EPSD	ICGC	8.283	Down-regulation
Atypical_PIKK_DNAPK_PRKDC_ST	P24928	POLR2A	P78527	PRKDC	S1668	S1665P	1665	Missense	distal	-3	no	8.429	8.567	EPSD	ICGC	8.283	Up-regulation
Atypical_PIKK_DNAPK_PRKDC_ST	P24928	POLR2A	P78527	PRKDC	S1670	S1665P	1665	Missense	distal	-5	no	9.950	9.579	EPSD	ICGC	8.283	Down-regulation
Atypical_PIKK_DNAPK_PRKDC_ST	P24928	POLR2A	P78527	PRKDC	S1829	A1835T	1835	Missense	distal	6	no	8.552	8.547	EPSD	ICGC	8.283	Down-regulation
Atypical_PIKK_DNAPK_PRKDC_ST	P24928	POLR2A	P78527	PRKDC	S1831	A1835T	1835	Missense	distal	4	no	9.114	9.053	EPSD	ICGC	8.283	Down-regulation
Atypical_PIKK_DNAPK_PRKDC_ST	P24928	POLR2A	P78527	PRKDC	S1836	A1835T	1835	Missense	proximal	-1	no	9.024	8.129	EPSD	ICGC	8.283	Loss
Atypical_PIKK_DNAPK_PRKDC_ST	P24928	POLR2A	P78527	PRKDC	S1843	S1850C	1850	Missense	distal	7	no	8.811	7.350	EPSD	ICGC	8.283	Loss
Atypical_PIKK_DNAPK_PRKDC_ST	P24928	POLR2A	P78527	PRKDC	S1845	S1850C	1850	Missense	distal	5	no	9.704	9.504	EPSD	ICGC	8.283	Down-regulation
Atypical_PIKK_DNAPK_PRKDC_ST	P24928	POLR2A	P78527	PRKDC	S1847	S1850C	1850	Missense	distal	3	no	8.448	8.087	EPSD	ICGC	8.283	Loss
Atypical_PIKK_DNAPK_PRKDC_ST	P24928	POLR2A	P78527	PRKDC	S1847	T1854P	1854	Missense	distal	7	no	8.448	9.168	EPSD	ICGC	8.283	Up-regulation
Atypical_PIKK_DNAPK_PRKDC_ST	P24928	POLR2A	P78527	PRKDC	S1850	S1850C	1850	Missense	central	0	yes	10.395	0.000	EPSD	ICGC	8.283	Loss
Atypical_PIKK_DNAPK_PRKDC_ST	P24928	POLR2A	P78527	PRKDC	S1850	T1854P	1854	Missense	distal	4	no	10.395	10.411	EPSD	ICGC	8.283	Up-regulation
Atypical_PIKK_DNAPK_PRKDC_ST	P24928	POLR2A	P78527	PRKDC	S1868	S1861L	1861	Missense	distal	-7	no	8.412	7.945	EPSD	ICGC	8.283	Loss
Atypical_PIKK_DNAPK_PRKDC_ST	P24928	POLR2A	P78527	PRKDC	T1894	P1890S	1890	Missense	distal	-4	no	8.292	8.693	EPSD	ICGC	8.283	Up-regulation
Atypical_PIKK_DNAPK_PRKDC_ST	P24928	POLR2A	P78527	PRKDC	S1917	S1920F	1920	Missense	distal	3	no	8.327	8.042	EPSD	ICGC	8.283	Loss
Atypical_PIKK_DNAPK_PRKDC_ST	P24928	POLR2A	P78527	PRKDC	S1917	P1921H	1921	Missense	distal	4	no	8.327	8.337	EPSD	ICGC	8.283	Up-regulation
Atypical_PIKK_DNAPK_PRKDC_ST	P24928	POLR2A	P78527	PRKDC	S1924	S1927I	1927	Missense	distal	3	no	8.669	7.729	EPSD	ICGC	8.283	Loss
Atypical_PIKK_DNAPK_PRKDC_ST	P24928	POLR2A	P78527	PRKDC	S1924	S1920F	1920	Missense	distal	-4	no	8.669	8.154	EPSD	ICGC	8.283	Loss
Atypical_PIKK_DNAPK_PRKDC_ST	P24928	POLR2A	P78527	PRKDC	S1924	P1921H	1921	Missense	distal	-3	no	8.669	8.675	EPSD	ICGC	8.283	Up-regulation
Atypical_PIKK_DNAPK_PRKDC_ST	P24928	POLR2A	P78527	PRKDC	S1931	S1927I	1927	Missense	distal	-4	no	9.179	7.915	EPSD	ICGC	8.283	Loss
Atypical_PIKK_DNAPK_PRKDC_ST	P24928	POLR2A	P78527	PRKDC	S1931	S1938P	1938	Missense	distal	7	no	9.179	9.052	EPSD	ICGC	8.283	Down-regulation
Atypical_PIKK_DNAPK_PRKDC_ST	P24928	POLR2A	P78527	PRKDC	S1948	P1952H	1952	Missense	distal	4	no	8.370	8.379	EPSD	ICGC	8.283	Up-regulation
Atypical_PIKK_DNAPK_PRKDC_ST	P24928	POLR2A	P78527	PRKDC	S1951	P1952H	1952	Missense	proximal	1	no	8.952	3.097	EPSD	ICGC	8.283	Loss
Atypical_PIKK_DNAPK_PRKDC_ST	P24928	POLR2A	P78527	PRKDC	S1955	P1952H	1952	Missense	distal	-3	no	8.902	8.908	EPSD	ICGC	8.283	Up-regulation
Atypical_PIKK_DNAPK_PRKDC_ST	P24928	POLR2A	P78527	PRKDC	S1962	P1963L	1963	Missense	proximal	1	no	8.871	8.810	EPSD	ICGC	8.283	Down-regulation
Atypical_PIKK_DNAPK_PRKDC_ST	P24928	POLR2A	P78527	PRKDC	S1966	P1963L	1963	Missense	distal	-3	no	8.986	8.786	EPSD	ICGC	8.283	Down-regulation
Atypical_PIKK_DNAPK_PRKDC_ST	Q15648	MED1	P78527	PRKDC	S18	L23H	23	Missense	distal	5	no	10.981	11.004	EPSD	ICGC;COSMIC	8.283	Up-regulation
Atypical_PIKK_DNAPK_PRKDC_ST	Q15648	MED1	P78527	PRKDC	T212	P213A	213	Missense	proximal	1	no	9.524	8.700	EPSD	ICGC;COSMIC	8.283	Down-regulation
Atypical_PIKK_DNAPK_PRKDC_ST	Q15648	MED1	P78527	PRKDC	T212	R214K	214	Missense	proximal	2	no	9.524	9.456	EPSD	ICGC;COSMIC	8.283	Down-regulation
Atypical_PIKK_DNAPK_PRKDC_ST	Q15648	MED1	P78527	PRKDC	S387	R386Q	386	Missense	proximal	-1	no	9.550	11.082	EPSD	ICGC	8.283	Up-regulation
Atypical_PIKK_DNAPK_PRKDC_ST	Q15648	MED1	P78527	PRKDC	S387	P383Q	383	Missense	distal	-4	no	9.550	10.054	EPSD	ICGC	8.283	Up-regulation
Atypical_PIKK_DNAPK_PRKDC_ST	Q15648	MED1	P78527	PRKDC	S387	P381S	381	Missense	distal	-6	no	9.550	9.914	EPSD	ICGC	8.283	Up-regulation
Atypical_PIKK_DNAPK_PRKDC_ST	Q15648	MED1	P78527	PRKDC	S599	F595S	595	Missense	distal	-4	no	10.103	10.619	EPSD	ICGC;COSMIC	8.283	Up-regulation
Atypical_PIKK_DNAPK_PRKDC_ST	Q15648	MED1	P78527	PRKDC	S743	P749L	749	Missense	distal	6	no	12.505	12.494	EPSD	ICGC;COSMIC	8.283	Down-regulation
Atypical_PIKK_DNAPK_PRKDC_ST	Q15648	MED1	P78527	PRKDC	S743	P748R	748	Missense	distal	5	no	12.505	12.332	EPSD	ICGC	8.283	Down-regulation
Atypical_PIKK_DNAPK_PRKDC_ST	Q15648	MED1	P78527	PRKDC	T747	P749L	749	Missense	proximal	2	no	10.493	9.535	EPSD	ICGC;COSMIC	8.283	Down-regulation
Atypical_PIKK_DNAPK_PRKDC_ST	Q15648	MED1	P78527	PRKDC	T747	P748R	748	Missense	proximal	1	no	10.493	4.559	EPSD	ICGC	8.283	Loss
Atypical_PIKK_DNAPK_PRKDC_ST	Q15648	MED1	P78527	PRKDC	T751	P749L	749	Missense	proximal	-2	no	9.326	9.324	EPSD	ICGC;COSMIC	8.283	Down-regulation
Atypical_PIKK_DNAPK_PRKDC_ST	Q15648	MED1	P78527	PRKDC	T751	P748R	748	Missense	distal	-3	no	9.326	8.936	EPSD	ICGC	8.283	Down-regulation
Atypical_PIKK_DNAPK_PRKDC_ST	Q15648	MED1	P78527	PRKDC	S816	S823C	823	Missense	distal	7	no	13.784	12.323	EPSD	ICGC;COSMIC	8.283	Down-regulation
Atypical_PIKK_DNAPK_PRKDC_ST	Q15648	MED1	P78527	PRKDC	S872	F865V	865	Missense	distal	-7	no	12.765	12.335	EPSD	ICGC;COSMIC	8.283	Down-regulation
Atypical_PIKK_DNAPK_PRKDC_ST	Q15648	MED1	P78527	PRKDC	S887	D891Y	891	Missense	distal	4	no	12.552	12.562	EPSD	ICGC;COSMIC	8.283	Up-regulation
Atypical_PIKK_DNAPK_PRKDC_ST	Q15648	MED1	P78527	PRKDC	S1000	D1007H	1007	Missense	distal	7	no	8.369	8.285	EPSD	ICGC;COSMIC	8.283	Down-regulation
Atypical_PIKK_DNAPK_PRKDC_ST	Q15648	MED1	P78527	PRKDC	S1049	T1051I	1051	Missense	proximal	2	no	11.137	9.259	EPSD	ICGC;COSMIC	8.283	Down-regulation
Atypical_PIKK_DNAPK_PRKDC_ST	Q15648	MED1	P78527	PRKDC	T1051	T1051I	1051	Missense	central	0	yes	8.611	0.000	EPSD	ICGC;COSMIC	8.283	Loss
Atypical_PIKK_DNAPK_PRKDC_ST	Q15648	MED1	P78527	PRKDC	S1185	S1192F	1192	Missense	distal	7	no	8.517	7.815	EPSD	ICGC;GDSC;CCLE	8.283	Loss
Atypical_PIKK_DNAPK_PRKDC_ST	Q15648	MED1	P78527	PRKDC	S1192	S1192F	1192	Missense	central	0	yes	8.897	0.000	EPSD	ICGC;GDSC;CCLE	8.283	Loss
Atypical_PIKK_DNAPK_PRKDC_ST	Q15648	MED1	P78527	PRKDC	S1207	P1208Q	1208	Missense	proximal	1	no	5.792	10.273	EPSD	ICGC	8.283	Gain
Atypical_PIKK_DNAPK_PRKDC_ST	Q15648	MED1	P78527	PRKDC	S1254	S1251Y	1251	Missense	distal	-3	no	9.536	9.775	EPSD	ICGC	8.283	Up-regulation
Atypical_PIKK_DNAPK_PRKDC_ST	Q15648	MED1	P78527	PRKDC	S1256	S1251Y	1251	Missense	distal	-5	no	12.287	11.941	EPSD	ICGC	8.283	Down-regulation
Atypical_PIKK_DNAPK_PRKDC_ST	Q15648	MED1	P78527	PRKDC	S1283	N1285K	1285	Missense	proximal	2	no	12.970	12.550	EPSD	ICGC	8.283	Down-regulation
Atypical_PIKK_DNAPK_PRKDC_ST	Q15648	MED1	P78527	PRKDC	S1371	T1378N	1378	Missense	distal	7	no	8.518	8.808	EPSD	ICGC	8.283	Up-regulation
Atypical_PIKK_DNAPK_PRKDC_ST	Q15648	MED1	P78527	PRKDC	S1371	G1369R	1369	Missense	proximal	-2	no	8.518	8.573	EPSD	ICGC;COSMIC	8.283	Up-regulation
Atypical_PIKK_DNAPK_PRKDC_ST	Q15648	MED1	P78527	PRKDC	S1417	K1412R	1412	Missense	distal	-5	no	8.472	8.033	EPSD	ICGC;COSMIC	8.283	Loss
Atypical_PIKK_DNAPK_PRKDC_ST	Q15648	MED1	P78527	PRKDC	T1457	E1464K	1464	Missense	distal	7	no	10.753	9.940	PhosphoSitePlus	ICGC	8.283	Down-regulation
Atypical_PIKK_DNAPK_PRKDC_ST	Q15648	MED1	P78527	PRKDC	S1561	D1555E	1555	Missense	distal	-6	no	11.063	11.214	EPSD	ICGC	8.283	Up-regulation
Atypical_PIKK_DNAPK_PRKDC_ST	Q15648	MED1	P78527	PRKDC	S1561	S1561R	1561	Missense	central	0	yes	11.063	0.000	EPSD	ICGC;COSMIC	8.283	Loss
Atypical_PIKK_DNAPK_PRKDC_ST	P07954	FH	P78527	PRKDC	S46	F50I	50	Missense	distal	4	no	12.660	12.613	EPSD	ICGC	8.283	Down-regulation
Atypical_PIKK_DNAPK_PRKDC_ST	P07954	FH	P78527	PRKDC	S46	F50L	50	Missense	distal	4	no	12.660	12.665	EPSD	ICGC	8.283	Up-regulation
Atypical_PIKK_DNAPK_PRKDC_ST	P07954	FH	P78527	PRKDC	T236	R233H	233	Missense	distal	-3	no	10.566	10.962	PhosphoSitePlus	ICGC;COSMIC;CCLE	8.283	Up-regulation
Atypical_PIKK_DNAPK_PRKDC_ST	P07954	FH	P78527	PRKDC	T236	R233C	233	Missense	distal	-3	no	10.566	10.582	PhosphoSitePlus	ICGC;COSMIC	8.283	Up-regulation
Atypical_PIKK_DNAPK_PRKDC_ST	P07954	FH	P78527	PRKDC	T236	R233S	233	Missense	distal	-3	no	10.566	10.818	PhosphoSitePlus	ICGC	8.283	Up-regulation
Atypical_PIKK_DNAPK_PRKDC_ST	O43918	AIRE	P78527	PRKDC	T68	L75P	75	Missense	distal	7	no	14.219	14.846	PhosphoSitePlus;EPSD	ICGC	8.283	Up-regulation
Atypical_PIKK_DNAPK_PRKDC_ST	O43918	AIRE	P78527	PRKDC	S107	R110Q	110	Missense	distal	3	no	12.995	13.610	EPSD	ICGC;GDSC;CCLE	8.283	Up-regulation
Atypical_PIKK_DNAPK_PRKDC_ST	O43918	AIRE	P78527	PRKDC	S107	G112R	112	Missense	distal	5	no	12.995	12.905	EPSD	ICGC	8.283	Down-regulation
Atypical_PIKK_DNAPK_PRKDC_ST	O43918	AIRE	P78527	PRKDC	S107	Q108K	108	Missense	proximal	1	no	12.995	1.790	EPSD	ICGC;COSMIC	8.283	Loss
Atypical_PIKK_DNAPK_PRKDC_ST	O43918	AIRE	P78527	PRKDC	S156	R149W	149	Missense	distal	-7	no	10.677	9.869	EPSD;PhosphoSitePlus	ICGC	8.283	Down-regulation
Atypical_PIKK_DNAPK_PRKDC_ST	O43918	AIRE	P78527	PRKDC	T232	G228R	228	Missense	distal	-4	no	9.296	9.146	EPSD	ICGC	8.283	Down-regulation
Atypical_PIKK_DNAPK_PRKDC_ST	O43918	AIRE	P78527	PRKDC	T232	G228W	228	Missense	distal	-4	no	9.296	8.820	EPSD	ICGC	8.283	Down-regulation
Atypical_PIKK_DNAPK_PRKDC_ST	P31270	HOXA11	P78527	PRKDC	S98	P97A	97	Missense	proximal	-1	no	9.115	9.184	EPSD;PhosphoSitePlus	ICGC;COSMIC;GDSC	8.283	Up-regulation
Atypical_PIKK_DNAPK_PRKDC_ST	P31270	HOXA11	P78527	PRKDC	S98	C93Y	93	Missense	distal	-5	no	9.115	9.227	EPSD;PhosphoSitePlus	ICGC;COSMIC	8.283	Up-regulation
Atypical_PIKK_DNAPK_PRKDC_ST	P31270	HOXA11	P78527	PRKDC	S98	S98R	98	Missense	central	0	yes	9.115	0.000	EPSD;PhosphoSitePlus	ICGC;COSMIC	8.283	Loss
Atypical_PIKK_DNAPK_PRKDC_ST	P31270	HOXA11	P78527	PRKDC	S221	S220R	220	Missense	proximal	-1	no	9.677	8.935	EPSD	ICGC	8.283	Down-regulation
Atypical_PIKK_DNAPK_PRKDC_ST	P31270	HOXA11	P78527	PRKDC	S221	S220N	220	Missense	proximal	-1	no	9.677	9.686	EPSD	ICGC	8.283	Up-regulation
Atypical_PIKK_DNAPK_PRKDC_ST	P31270	HOXA11	P78527	PRKDC	S221	S225F	225	Missense	distal	4	no	9.677	9.652	EPSD	ICGC;COSMIC;CCLE	8.283	Down-regulation
Atypical_PIKK_DNAPK_PRKDC_ST	P31270	HOXA11	P78527	PRKDC	S221	R214G	214	Missense	distal	-7	no	9.677	9.801	EPSD	ICGC;COSMIC	8.283	Up-regulation
Atypical_PIKK_DNAPK_PRKDC_ST	P31270	HOXA11	P78527	PRKDC	S224	S225F	225	Missense	proximal	1	no	6.894	8.871	EPSD	ICGC;COSMIC;CCLE	8.283	Gain
Atypical_PIKK_DNAPK_PRKDC_ST	P11831	SRF	P78527	PRKDC	S16	G19W	19	Missense	distal	3	no	8.328	7.978	EPSD	ICGC	8.283	Loss
Atypical_PIKK_DNAPK_PRKDC_ST	P11831	SRF	P78527	PRKDC	S16	G15V	15	Missense	proximal	-1	no	8.328	7.689	EPSD	ICGC;COSMIC	8.283	Loss
Atypical_PIKK_DNAPK_PRKDC_ST	P11831	SRF	P78527	PRKDC	S21	G19W	19	Missense	proximal	-2	no	8.920	9.077	EPSD	ICGC	8.283	Up-regulation
Atypical_PIKK_DNAPK_PRKDC_ST	P11831	SRF	P78527	PRKDC	S21	G15V	15	Missense	distal	-6	no	8.920	8.503	EPSD	ICGC;COSMIC	8.283	Down-regulation
Atypical_PIKK_DNAPK_PRKDC_ST	P11831	SRF	P78527	PRKDC	S101	G108C	108	Missense	distal	7	no	8.545	7.792	EPSD	ICGC	8.283	Loss
Atypical_PIKK_DNAPK_PRKDC_ST	P11831	SRF	P78527	PRKDC	S101	G97A	97	Missense	distal	-4	no	8.545	8.916	EPSD	ICGC	8.283	Up-regulation
Atypical_PIKK_DNAPK_PRKDC_ST	P11831	SRF	P78527	PRKDC	S101	E104D	104	Missense	distal	3	no	8.545	8.339	EPSD	ICGC;COSMIC	8.283	Down-regulation
Atypical_PIKK_DNAPK_PRKDC_ST	P11831	SRF	P78527	PRKDC	S224	S221L	221	Missense	distal	-3	no	9.633	9.571	EPSD	ICGC;COSMIC	8.283	Down-regulation
Atypical_PIKK_DNAPK_PRKDC_ST	P11831	SRF	P78527	PRKDC	S309	P305Q	305	Missense	distal	-4	no	7.841	8.345	EPSD	ICGC;COSMIC	8.283	Gain
Atypical_PIKK_DNAPK_PRKDC_ST	P11831	SRF	P78527	PRKDC	S311	P305Q	305	Missense	distal	-6	no	8.035	8.504	EPSD	ICGC;COSMIC	8.283	Gain
Atypical_PIKK_DNAPK_PRKDC_ST	P11831	SRF	P78527	PRKDC	S435	S439Y	439	Missense	distal	4	no	13.175	13.182	EPSD;PhosphoSitePlus	ICGC;COSMIC	8.283	Up-regulation
Atypical_PIKK_DNAPK_PRKDC_ST	P11831	SRF	P78527	PRKDC	S435	S435Y	435	Missense	central	0	yes	13.175	0.000	EPSD;PhosphoSitePlus	ICGC;COSMIC	8.283	Loss
Atypical_PIKK_DNAPK_PRKDC_ST	P11831	SRF	P78527	PRKDC	S446	V448F	448	Missense	proximal	2	no	13.011	13.567	PhosphoSitePlus;EPSD	ICGC;COSMIC	8.283	Up-regulation
Atypical_PIKK_DNAPK_PRKDC_ST	P11831	SRF	P78527	PRKDC	S446	S439Y	439	Missense	distal	-7	no	13.011	12.583	PhosphoSitePlus;EPSD	ICGC;COSMIC	8.283	Down-regulation
Atypical_PIKK_DNAPK_PRKDC_ST	P31749	AKT1	P78527	PRKDC	T211	H207N	207	Missense	distal	-4	no	8.453	8.574	EPSD	ICGC;COSMIC	8.283	Up-regulation
Atypical_PIKK_DNAPK_PRKDC_ST	P31749	AKT1	P78527	PRKDC	T312	T305N	305	Missense	distal	-7	no	9.481	9.485	EPSD	ICGC	8.283	Up-regulation
Atypical_PIKK_DNAPK_PRKDC_ST	P31749	AKT1	P78527	PRKDC	S422	K420T	420	Missense	proximal	-2	no	8.605	8.629	EPSD	ICGC	8.283	Up-regulation
Atypical_PIKK_DNAPK_PRKDC_ST	P31749	AKT1	P78527	PRKDC	S457	M458L	458	Missense	proximal	1	no	2.750	10.021	EPSD	ICGC;COSMIC	8.283	Gain
Atypical_PIKK_DNAPK_PRKDC_ST	P31749	AKT1	P78527	PRKDC	S473	Q471K	471	Missense	proximal	-2	no	9.351	9.519	PhosphoSitePlus	ICGC	8.283	Up-regulation
Atypical_PIKK_DNAPK_PRKDC_ST	P31749	AKT1	P78527	PRKDC	S473	S477R	477	Missense	distal	4	no	9.351	9.313	PhosphoSitePlus	ICGC	8.283	Down-regulation
Atypical_PIKK_DNAPK_PRKDC_ST	Q9H4A6	GOLPH3	P78527	PRKDC	T5	R7L	7	Missense	proximal	2	no	9.308	9.395	EPSD	ICGC;COSMIC	8.283	Up-regulation
Atypical_PIKK_DNAPK_PRKDC_ST	Q9H4A6	GOLPH3	P78527	PRKDC	T143	H139L	139	Missense	distal	-4	no	14.782	14.480	EPSD;PhosphoSitePlus	ICGC;COSMIC	8.283	Down-regulation
Atypical_PIKK_DNAPK_PRKDC_ST	Q9H4A6	GOLPH3	P78527	PRKDC	T143	Q144K	144	Missense	proximal	1	no	14.782	3.577	EPSD;PhosphoSitePlus	ICGC;COSMIC	8.283	Loss
Atypical_PIKK_DNAPK_PRKDC_ST	O96017	CHEK2	P78527	PRKDC	S33	G37C	37	Missense	distal	4	no	12.863	12.826	EPSD	ICGC;COSMIC	8.283	Down-regulation
Atypical_PIKK_DNAPK_PRKDC_ST	O96017	CHEK2	P78527	PRKDC	S35	G37C	37	Missense	proximal	2	no	14.547	14.173	EPSD	ICGC;COSMIC	8.283	Down-regulation
Atypical_PIKK_DNAPK_PRKDC_ST	O96017	CHEK2	P78527	PRKDC	S50	M46I	46	Missense	distal	-4	no	15.189	14.650	EPSD	ICGC;COSMIC	8.283	Down-regulation
Atypical_PIKK_DNAPK_PRKDC_ST	O96017	CHEK2	P78527	PRKDC	S50	S49F	49	Missense	proximal	-1	no	15.189	15.453	EPSD	ICGC;COSMIC	8.283	Up-regulation
Atypical_PIKK_DNAPK_PRKDC_ST	O96017	CHEK2	P78527	PRKDC	S50	T45M	45	Missense	distal	-5	no	15.189	14.960	EPSD	ICGC;COSMIC	8.283	Down-regulation
Atypical_PIKK_DNAPK_PRKDC_ST	O96017	CHEK2	P78527	PRKDC	S260	A257S	257	Missense	distal	-3	no	8.348	8.412	EPSD	ICGC;COSMIC	8.283	Up-regulation
Atypical_PIKK_DNAPK_PRKDC_ST	O96017	CHEK2	P78527	PRKDC	S260	A264T	264	Missense	distal	4	no	8.348	8.288	EPSD	ICGC	8.283	Down-regulation
Atypical_PIKK_DNAPK_PRKDC_ST	O96017	CHEK2	P78527	PRKDC	S357	E359K	359	Missense	proximal	2	no	11.047	9.071	EPSD	ICGC;COSMIC	8.283	Down-regulation
Atypical_PIKK_DNAPK_PRKDC_ST	O96017	CHEK2	P78527	PRKDC	S357	L363F	363	Missense	distal	6	no	11.047	11.051	EPSD	ICGC;COSMIC	8.283	Up-regulation
Atypical_PIKK_DNAPK_PRKDC_ST	O96017	CHEK2	P78527	PRKDC	S357	L355R	355	Missense	proximal	-2	no	11.047	11.151	EPSD	ICGC	8.283	Up-regulation
Atypical_PIKK_DNAPK_PRKDC_ST	O96017	CHEK2	P78527	PRKDC	S357	E351D	351	Missense	distal	-6	no	11.047	10.896	EPSD	ICGC;COSMIC	8.283	Down-regulation
Atypical_PIKK_DNAPK_PRKDC_ST	O96017	CHEK2	P78527	PRKDC	S357	L354V	354	Missense	distal	-3	no	11.047	10.862	EPSD	ICGC;COSMIC	8.283	Down-regulation
Atypical_PIKK_DNAPK_PRKDC_ST	O96017	CHEK2	P78527	PRKDC	T383	Y390N	390	Missense	distal	7	no	8.602	8.500	EPSD;PhosphoSitePlus	ICGC;COSMIC	8.283	Down-regulation
Atypical_PIKK_DNAPK_PRKDC_ST	O96017	CHEK2	P78527	PRKDC	T383	E377K	377	Missense	distal	-6	no	8.602	8.392	EPSD;PhosphoSitePlus	ICGC;COSMIC	8.283	Down-regulation
Atypical_PIKK_DNAPK_PRKDC_ST	O96017	CHEK2	P78527	PRKDC	T383	S379F	379	Missense	distal	-4	no	8.602	8.087	EPSD;PhosphoSitePlus	ICGC;COSMIC	8.283	Loss
Atypical_PIKK_DNAPK_PRKDC_ST	O96017	CHEK2	P78527	PRKDC	T383	L380V	380	Missense	distal	-3	no	8.602	8.417	EPSD;PhosphoSitePlus	ICGC;COSMIC	8.283	Down-regulation
Atypical_PIKK_DNAPK_PRKDC_ST	O96017	CHEK2	P78527	PRKDC	T383	G386V	386	Missense	distal	3	no	8.602	8.274	EPSD;PhosphoSitePlus	ICGC;COSMIC	8.283	Loss
Atypical_PIKK_DNAPK_PRKDC_ST	O96017	CHEK2	P78527	PRKDC	T383	T378A	378	Missense	distal	-5	no	8.602	8.707	EPSD;PhosphoSitePlus	ICGC	8.283	Up-regulation
Atypical_PIKK_DNAPK_PRKDC_ST	O96017	CHEK2	P78527	PRKDC	T387	Y390N	390	Missense	distal	3	no	9.198	9.395	EPSD;PhosphoSitePlus	ICGC;COSMIC	8.283	Up-regulation
Atypical_PIKK_DNAPK_PRKDC_ST	O96017	CHEK2	P78527	PRKDC	T387	A392V	392	Missense	distal	5	no	9.198	9.020	EPSD;PhosphoSitePlus	ICGC;COSMIC	8.283	Down-regulation
Atypical_PIKK_DNAPK_PRKDC_ST	O96017	CHEK2	P78527	PRKDC	T387	L380V	380	Missense	distal	-7	no	9.198	8.691	EPSD;PhosphoSitePlus	ICGC;COSMIC	8.283	Down-regulation
Atypical_PIKK_DNAPK_PRKDC_ST	O96017	CHEK2	P78527	PRKDC	T387	G386V	386	Missense	proximal	-1	no	9.198	8.559	EPSD;PhosphoSitePlus	ICGC;COSMIC	8.283	Down-regulation
Atypical_PIKK_DNAPK_PRKDC_ST	O96017	CHEK2	P78527	PRKDC	T387	L391F	391	Missense	distal	4	no	9.198	9.192	EPSD;PhosphoSitePlus	ICGC;COSMIC	8.283	Down-regulation
Atypical_PIKK_DNAPK_PRKDC_ST	O96017	CHEK2	P78527	PRKDC	T432	Q433E	433	Missense	proximal	1	no	9.582	1.847	EPSD	ICGC;COSMIC	8.283	Loss
Atypical_PIKK_DNAPK_PRKDC_ST	O96017	CHEK2	P78527	PRKDC	T432	S428F	428	Missense	distal	-4	no	9.582	9.067	EPSD	ICGC;COSMIC	8.283	Down-regulation
Atypical_PIKK_DNAPK_PRKDC_ST	O96017	CHEK2	P78527	PRKDC	T432	H430Y	430	Missense	proximal	-2	no	9.582	9.538	EPSD	ICGC;COSMIC	8.283	Down-regulation
Atypical_PIKK_DNAPK_PRKDC_ST	P42575	CASP2	P78527	PRKDC	S139	C134F	134	Missense	distal	-5	no	9.692	9.740	PhosphoSitePlus	ICGC	8.283	Up-regulation
Atypical_PIKK_DNAPK_PRKDC_ST	P42575	CASP2	P78527	PRKDC	S164	N167T	167	Missense	distal	3	no	11.019	10.657	EPSD	ICGC	8.283	Down-regulation
Atypical_PIKK_DNAPK_PRKDC_ST	P42575	CASP2	P78527	PRKDC	S340	K335N	335	Missense	distal	-5	no	8.405	8.283	EPSD	ICGC;COSMIC	8.283	Down-regulation
Atypical_PIKK_DNAPK_PRKDC_ST	P42575	CASP2	P78527	PRKDC	S340	E344D	344	Missense	distal	4	no	8.405	8.378	EPSD	ICGC;COSMIC	8.283	Down-regulation
Atypical_PIKK_DNAPK_PRKDC_ST	P42575	CASP2	P78527	PRKDC	S340	P341T	341	Missense	proximal	1	no	8.405	2.340	EPSD	ICGC;COSMIC	8.283	Loss
Atypical_PIKK_DNAPK_PRKDC_ST	Q9BQ15	NABP2	P78527	PRKDC	T117	A120S	120	Missense	distal	3	no	13.888	13.953	EPSD	ICGC	8.283	Up-regulation
Atypical_PIKK_DNAPK_PRKDC_ST	Q9BQ15	NABP2	P78527	PRKDC	S141	S147F	147	Missense	distal	6	no	8.297	8.300	EPSD	ICGC;COSMIC	8.283	Up-regulation
Atypical_PIKK_DNAPK_PRKDC_ST	Q9BQ15	NABP2	P78527	PRKDC	S141	A142S	142	Missense	proximal	1	no	8.297	4.766	EPSD	ICGC;COSMIC	8.283	Loss
Atypical_PIKK_DNAPK_PRKDC_ST	Q9BQ15	NABP2	P78527	PRKDC	S141	S144F	144	Missense	distal	3	no	8.297	8.012	EPSD	ICGC	8.283	Loss
Atypical_PIKK_DNAPK_PRKDC_ST	P49917	LIG4	P78527	PRKDC	S199	Q200P	200	Missense	proximal	1	no	11.243	6.762	EPSD	ICGC;COSMIC	8.283	Loss
Atypical_PIKK_DNAPK_PRKDC_ST	P49917	LIG4	P78527	PRKDC	S199	S205Y	205	Missense	distal	6	no	11.243	11.256	EPSD	ICGC	8.283	Up-regulation
Atypical_PIKK_DNAPK_PRKDC_ST	P49917	LIG4	P78527	PRKDC	T788	E786K	786	Missense	proximal	-2	no	9.154	9.243	EPSD	ICGC	8.283	Up-regulation
Atypical_PIKK_DNAPK_PRKDC_ST	P49917	LIG4	P78527	PRKDC	T788	L795R	795	Missense	distal	7	no	9.154	8.751	EPSD	ICGC;COSMIC	8.283	Down-regulation
Atypical_PIKK_DNAPK_PRKDC_ST	P08670	VIM	P78527	PRKDC	T37	V31A	31	Missense	distal	-6	no	8.227	8.983	EPSD	ICGC	8.283	Gain
Atypical_PIKK_DNAPK_PRKDC_ST	P08670	VIM	P78527	PRKDC	T37	R36S	36	Missense	proximal	-1	no	8.227	8.969	EPSD	ICGC;COSMIC	8.283	Gain
Atypical_PIKK_DNAPK_PRKDC_ST	P08670	VIM	P78527	PRKDC	S56	S55L	55	Missense	proximal	-1	no	9.041	9.079	EPSD;PhosphoSitePlus	ICGC	8.283	Up-regulation
Atypical_PIKK_DNAPK_PRKDC_ST	P08670	VIM	P78527	PRKDC	S56	A54G	54	Missense	proximal	-2	no	9.041	9.123	EPSD;PhosphoSitePlus	ICGC	8.283	Up-regulation
Atypical_PIKK_DNAPK_PRKDC_ST	P08670	VIM	P78527	PRKDC	S56	A62V	62	Missense	distal	6	no	9.041	9.027	EPSD;PhosphoSitePlus	ICGC	8.283	Down-regulation
Atypical_PIKK_DNAPK_PRKDC_ST	P08670	VIM	P78527	PRKDC	T94	E95Q	95	Missense	proximal	1	no	2.179	9.914	EPSD	ICGC;COSMIC	8.283	Gain
Atypical_PIKK_DNAPK_PRKDC_ST	P08670	VIM	P78527	PRKDC	S144	R145L	145	Missense	proximal	1	no	3.273	9.145	EPSD	ICGC;COSMIC	8.283	Gain
Atypical_PIKK_DNAPK_PRKDC_ST	P08670	VIM	P78527	PRKDC	T202	R207G	207	Missense	distal	5	no	9.911	10.000	EPSD	ICGC;COSMIC	8.283	Up-regulation
Atypical_PIKK_DNAPK_PRKDC_ST	P08670	VIM	P78527	PRKDC	S214	V210I	210	Missense	distal	-4	no	10.423	9.985	EPSD	ICGC;COSMIC	8.283	Down-regulation
Atypical_PIKK_DNAPK_PRKDC_ST	P08670	VIM	P78527	PRKDC	S214	R207G	207	Missense	distal	-7	no	10.423	10.546	EPSD	ICGC;COSMIC	8.283	Up-regulation
Atypical_PIKK_DNAPK_PRKDC_ST	P08670	VIM	P78527	PRKDC	S278	R273H	273	Missense	distal	-5	no	8.729	9.181	EPSD	ICGC	8.283	Up-regulation
Atypical_PIKK_DNAPK_PRKDC_ST	P08670	VIM	P78527	PRKDC	S278	R273G	273	Missense	distal	-5	no	8.729	8.899	EPSD	ICGC	8.283	Up-regulation
Atypical_PIKK_DNAPK_PRKDC_ST	P08670	VIM	P78527	PRKDC	S339	R342C	342	Missense	distal	3	no	10.022	10.133	EPSD	ICGC	8.283	Up-regulation
Atypical_PIKK_DNAPK_PRKDC_ST	P08670	VIM	P78527	PRKDC	S339	R342S	342	Missense	distal	3	no	10.022	10.495	EPSD	ICGC;COSMIC	8.283	Up-regulation
Atypical_PIKK_DNAPK_PRKDC_ST	P08670	VIM	P78527	PRKDC	S339	E338D	338	Missense	proximal	-1	no	10.022	9.767	EPSD	ICGC	8.283	Down-regulation
Atypical_PIKK_DNAPK_PRKDC_ST	P08670	VIM	P78527	PRKDC	S430	L428P	428	Missense	proximal	-2	no	11.345	11.347	EPSD;PhosphoSitePlus	ICGC;COSMIC	8.283	Up-regulation
Atypical_PIKK_DNAPK_PRKDC_ST	P08670	VIM	P78527	PRKDC	S459	D463N	463	Missense	distal	4	no	12.148	12.172	PhosphoSitePlus;EPSD	ICGC;COSMIC	8.283	Up-regulation
Atypical_PIKK_DNAPK_PRKDC_ST	P08670	VIM	P78527	PRKDC	S459	S459C	459	Missense	central	0	yes	12.148	0.000	PhosphoSitePlus;EPSD	ICGC;COSMIC	8.283	Loss
Atypical_PIKK_DNAPK_PRKDC_ST	P18887	XRCC1	P78527	PRKDC	S14	S14R	14	Missense	central	0	yes	13.569	0.000	EPSD	ICGC;COSMIC	8.283	Loss
Atypical_PIKK_DNAPK_PRKDC_ST	P18887	XRCC1	P78527	PRKDC	S14	V10L	10	Missense	distal	-4	no	13.569	13.950	EPSD	ICGC;COSMIC	8.283	Up-regulation
Atypical_PIKK_DNAPK_PRKDC_ST	P18887	XRCC1	P78527	PRKDC	S151	R148L	148	Missense	distal	-3	no	9.442	9.632	EPSD	ICGC;COSMIC	8.283	Up-regulation
Atypical_PIKK_DNAPK_PRKDC_ST	P18887	XRCC1	P78527	PRKDC	S162	K164N	164	Missense	proximal	2	no	13.152	13.572	EPSD	ICGC;COSMIC	8.283	Up-regulation
Atypical_PIKK_DNAPK_PRKDC_ST	P18887	XRCC1	P78527	PRKDC	S220	A221S	221	Missense	proximal	1	no	9.152	5.621	EPSD	ICGC;COSMIC	8.283	Loss
Atypical_PIKK_DNAPK_PRKDC_ST	P18887	XRCC1	P78527	PRKDC	S224	A221S	221	Missense	distal	-3	no	8.853	8.917	EPSD	ICGC;COSMIC	8.283	Up-regulation
Atypical_PIKK_DNAPK_PRKDC_ST	P18887	XRCC1	P78527	PRKDC	S226	A221S	221	Missense	distal	-5	no	8.768	8.904	EPSD	ICGC;COSMIC	8.283	Up-regulation
Atypical_PIKK_DNAPK_PRKDC_ST	P18887	XRCC1	P78527	PRKDC	S241	P242S	242	Missense	proximal	1	no	8.463	4.108	EPSD	ICGC	8.283	Loss
Atypical_PIKK_DNAPK_PRKDC_ST	P18887	XRCC1	P78527	PRKDC	S241	G244W	244	Missense	distal	3	no	8.463	8.114	EPSD	ICGC;COSMIC	8.283	Loss
Atypical_PIKK_DNAPK_PRKDC_ST	P18887	XRCC1	P78527	PRKDC	T281	R280H	280	Missense	proximal	-1	no	8.237	9.290	EPSD	ICGC;COSMIC	8.283	Gain
Atypical_PIKK_DNAPK_PRKDC_ST	P18887	XRCC1	P78527	PRKDC	T281	P288S	288	Missense	distal	7	no	8.237	8.364	EPSD	ICGC;COSMIC	8.283	Gain
Atypical_PIKK_DNAPK_PRKDC_ST	P18887	XRCC1	P78527	PRKDC	T281	R280S	280	Missense	proximal	-1	no	8.237	8.979	EPSD	ICGC	8.283	Gain
Atypical_PIKK_DNAPK_PRKDC_ST	P18887	XRCC1	P78527	PRKDC	S371	Y370H	370	Missense	proximal	-1	no	11.590	11.563	PhosphoSitePlus	ICGC;COSMIC	8.283	Down-regulation
Atypical_PIKK_DNAPK_PRKDC_ST	P18887	XRCC1	P78527	PRKDC	S371	Q372K	372	Missense	proximal	1	no	11.590	0.385	PhosphoSitePlus	ICGC	8.283	Loss
Atypical_PIKK_DNAPK_PRKDC_ST	P18887	XRCC1	P78527	PRKDC	S371	T367N	367	Missense	distal	-4	no	11.590	12.213	PhosphoSitePlus	ICGC	8.283	Up-regulation
Atypical_PIKK_DNAPK_PRKDC_ST	P18887	XRCC1	P78527	PRKDC	T440	G444E	444	Missense	distal	4	no	13.840	13.870	EPSD	ICGC;COSMIC	8.283	Up-regulation
Atypical_PIKK_DNAPK_PRKDC_ST	P18887	XRCC1	P78527	PRKDC	T440	A442E	442	Missense	proximal	2	no	13.840	14.500	EPSD	ICGC	8.283	Up-regulation
Atypical_PIKK_DNAPK_PRKDC_ST	P18887	XRCC1	P78527	PRKDC	T440	Q441K	441	Missense	proximal	1	no	13.840	2.635	EPSD	ICGC	8.283	Loss
Atypical_PIKK_DNAPK_PRKDC_ST	P18887	XRCC1	P78527	PRKDC	S447	G444E	444	Missense	distal	-3	no	9.769	10.049	EPSD	ICGC;COSMIC	8.283	Up-regulation
Atypical_PIKK_DNAPK_PRKDC_ST	P18887	XRCC1	P78527	PRKDC	S447	P451T	451	Missense	distal	4	no	9.769	9.753	EPSD	ICGC	8.283	Down-regulation
Atypical_PIKK_DNAPK_PRKDC_ST	P18887	XRCC1	P78527	PRKDC	S447	P451H	451	Missense	distal	4	no	9.769	9.778	EPSD	ICGC	8.283	Up-regulation
Atypical_PIKK_DNAPK_PRKDC_ST	P18887	XRCC1	P78527	PRKDC	S447	A442E	442	Missense	distal	-5	no	9.769	9.924	EPSD	ICGC	8.283	Up-regulation
Atypical_PIKK_DNAPK_PRKDC_ST	P18887	XRCC1	P78527	PRKDC	S447	Q441K	441	Missense	distal	-6	no	9.769	9.494	EPSD	ICGC	8.283	Down-regulation
Atypical_PIKK_DNAPK_PRKDC_ST	P18887	XRCC1	P78527	PRKDC	T453	P451T	451	Missense	proximal	-2	no	11.500	11.546	EPSD	ICGC	8.283	Up-regulation
Atypical_PIKK_DNAPK_PRKDC_ST	P18887	XRCC1	P78527	PRKDC	T453	P451H	451	Missense	proximal	-2	no	11.500	11.471	EPSD	ICGC	8.283	Down-regulation
Atypical_PIKK_DNAPK_PRKDC_ST	Q9NUW8	TDP1	P78527	PRKDC	S15	D16Y	16	Missense	proximal	1	no	5.980	8.441	EPSD	ICGC	8.283	Gain
Atypical_PIKK_DNAPK_PRKDC_ST	Q9NUW8	TDP1	P78527	PRKDC	S18	S18N	18	Missense	central	0	yes	8.473	0.000	EPSD	ICGC;COSMIC	8.283	Loss
Atypical_PIKK_DNAPK_PRKDC_ST	Q9NUW8	TDP1	P78527	PRKDC	S18	D16Y	16	Missense	proximal	-2	no	8.473	8.470	EPSD	ICGC	8.283	Down-regulation
Atypical_PIKK_DNAPK_PRKDC_ST	Q9NUW8	TDP1	P78527	PRKDC	S18	S13F	13	Missense	distal	-5	no	8.473	8.063	EPSD	ICGC;COSMIC;GDSC;CCLE	8.283	Loss
Atypical_PIKK_DNAPK_PRKDC_ST	Q9NUW8	TDP1	P78527	PRKDC	S365	R361H	361	Missense	distal	-4	no	13.129	13.581	EPSD	ICGC	8.283	Up-regulation
Atypical_PIKK_DNAPK_PRKDC_ST	Q9NUW8	TDP1	P78527	PRKDC	S434	V435I	435	Missense	proximal	1	no	9.107	2.192	EPSD	ICGC;COSMIC	8.283	Loss
Atypical_PIKK_DNAPK_PRKDC_ST	Q9NUW8	TDP1	P78527	PRKDC	S434	S427I	427	Missense	distal	-7	no	9.107	7.551	EPSD	ICGC	8.283	Loss
Atypical_PIKK_DNAPK_PRKDC_ST	Q9NUW8	TDP1	P78527	PRKDC	S434	Y441C	441	Missense	distal	7	no	9.107	8.102	EPSD	ICGC;COSMIC	8.283	Loss
Atypical_PIKK_DNAPK_PRKDC_ST	Q9NUW8	TDP1	P78527	PRKDC	S434	S434Y	434	Missense	central	0	yes	9.107	0.000	EPSD	ICGC;COSMIC	8.283	Loss
Atypical_PIKK_DNAPK_PRKDC_ST	Q9NUW8	TDP1	P78527	PRKDC	S563	A561S	561	Missense	proximal	-2	no	13.591	13.601	EPSD	ICGC;COSMIC	8.283	Up-regulation
Atypical_PIKK_DNAPK_PRKDC_ST	Q9NUW8	TDP1	P78527	PRKDC	S563	A568S	568	Missense	distal	5	no	13.591	13.569	EPSD	ICGC	8.283	Down-regulation
Atypical_PIKK_DNAPK_PRKDC_ST	Q9NUW8	TDP1	P78527	PRKDC	S563	A568T	568	Missense	distal	5	no	13.591	13.425	EPSD	ICGC	8.283	Down-regulation
Atypical_PIKK_DNAPK_PRKDC_ST	Q8IZL8	PELP1	P78527	PRKDC	S7	L6M	6	Missense	proximal	-1	no	8.492	7.598	EPSD	ICGC	8.283	Loss
Atypical_PIKK_DNAPK_PRKDC_ST	Q8IZL8	PELP1	P78527	PRKDC	S10	L6M	6	Missense	distal	-4	no	10.189	9.909	EPSD	ICGC	8.283	Down-regulation
Atypical_PIKK_DNAPK_PRKDC_ST	Q8IZL8	PELP1	P78527	PRKDC	S13	P18T	18	Missense	distal	5	no	8.997	8.884	EPSD	ICGC	8.283	Down-regulation
Atypical_PIKK_DNAPK_PRKDC_ST	Q8IZL8	PELP1	P78527	PRKDC	S13	L6M	6	Missense	distal	-7	no	8.997	8.818	EPSD	ICGC	8.283	Down-regulation
Atypical_PIKK_DNAPK_PRKDC_ST	Q8IZL8	PELP1	P78527	PRKDC	S13	G20W	20	Missense	distal	7	no	8.997	7.885	EPSD	ICGC;COSMIC	8.283	Loss
Atypical_PIKK_DNAPK_PRKDC_ST	Q8IZL8	PELP1	P78527	PRKDC	S251	S245F	245	Missense	distal	-6	no	13.258	12.767	EPSD	ICGC	8.283	Down-regulation
Atypical_PIKK_DNAPK_PRKDC_ST	Q8IZL8	PELP1	P78527	PRKDC	T647	P648T	648	Missense	proximal	1	no	9.452	3.388	EPSD	ICGC	8.283	Loss
Atypical_PIKK_DNAPK_PRKDC_ST	Q8IZL8	PELP1	P78527	PRKDC	S991	P993L	993	Missense	proximal	2	no	10.083	9.125	EPSD	ICGC	8.283	Down-regulation
Atypical_PIKK_DNAPK_PRKDC_ST	Q8IZL8	PELP1	P78527	PRKDC	T1022	D1021Y	1021	Missense	proximal	-1	no	8.535	8.123	EPSD	ICGC	8.283	Loss
Atypical_PIKK_DNAPK_PRKDC_ST	Q8IZL8	PELP1	P78527	PRKDC	T1025	D1021Y	1021	Missense	distal	-4	no	8.851	8.644	EPSD	ICGC	8.283	Down-regulation
Atypical_PIKK_DNAPK_PRKDC_ST	P22415	USF1	P78527	PRKDC	S174	I178V	178	Missense	distal	4	no	10.449	10.473	EPSD	ICGC;COSMIC	8.283	Up-regulation
Atypical_PIKK_DNAPK_PRKDC_ST	P55895	RAG2	P78527	PRKDC	S20	G18D	18	Missense	proximal	-2	no	9.161	9.045	EPSD	ICGC;COSMIC	8.283	Down-regulation
Atypical_PIKK_DNAPK_PRKDC_ST	P55895	RAG2	P78527	PRKDC	S20	P17T	17	Missense	distal	-3	no	9.161	8.899	EPSD	ICGC;COSMIC	8.283	Down-regulation
Atypical_PIKK_DNAPK_PRKDC_ST	P55895	RAG2	P78527	PRKDC	S20	Q16H	16	Missense	distal	-4	no	9.161	8.915	EPSD	ICGC;COSMIC	8.283	Down-regulation
Atypical_PIKK_DNAPK_PRKDC_ST	P55895	RAG2	P78527	PRKDC	S365	E370D	370	Missense	distal	5	no	13.045	13.014	PhosphoSitePlus	ICGC;COSMIC	8.283	Down-regulation
Atypical_PIKK_DNAPK_PRKDC_ST	P55895	RAG2	P78527	PRKDC	S365	T369A	369	Missense	distal	4	no	13.045	13.106	PhosphoSitePlus	ICGC;COSMIC	8.283	Up-regulation
Atypical_PIKK_DNAPK_PRKDC_ST	P55072	VCP	P78527	PRKDC	S326	R322W	322	Missense	distal	-4	no	9.446	9.120	EPSD	ICGC;COSMIC	8.283	Down-regulation
Atypical_PIKK_DNAPK_PRKDC_ST	P55072	VCP	P78527	PRKDC	S784	P783T	783	Missense	proximal	-1	no	12.020	11.195	PhosphoSitePlus	ICGC;COSMIC	8.283	Down-regulation
Atypical_PIKK_DNAPK_PRKDC_ST	P52945	PDX1	P78527	PRKDC	T11	E4K	4	Missense	distal	-7	no	13.990	13.736	PhosphoSitePlus	ICGC	8.283	Down-regulation
Atypical_PIKK_DNAPK_PRKDC_ST	P52945	PDX1	P78527	PRKDC	T11	P17Q	17	Missense	distal	6	no	13.990	13.997	PhosphoSitePlus	ICGC;COSMIC	8.283	Up-regulation
Atypical_PIKK_DNAPK_PRKDC_ST	P52945	PDX1	P78527	PRKDC	T11	T11P	11	Missense	central	0	yes	13.990	0.000	PhosphoSitePlus	ICGC	8.283	Loss
Atypical_PIKK_DNAPK_PRKDC_ST	P52945	PDX1	P78527	PRKDC	S273	P279S	279	Missense	distal	6	no	9.610	9.600	EPSD	ICGC	8.283	Down-regulation
Atypical_PIKK_DNAPK_PRKDC_ST	P52945	PDX1	P78527	PRKDC	S273	P276T	276	Missense	distal	3	no	9.610	9.336	EPSD	ICGC;COSMIC	8.283	Down-regulation
Atypical_PIKK_DNAPK_PRKDC_ST	Q8TCS8	PNPT1	P78527	PRKDC	S93	P97H	97	Missense	distal	4	no	10.215	10.224	EPSD	ICGC;COSMIC	8.283	Up-regulation
Atypical_PIKK_DNAPK_PRKDC_ST	Q8TCS8	PNPT1	P78527	PRKDC	S93	P92H	92	Missense	proximal	-1	no	10.215	10.186	EPSD	ICGC;COSMIC	8.283	Down-regulation
Atypical_PIKK_DNAPK_PRKDC_ST	Q8TCS8	PNPT1	P78527	PRKDC	S93	P97L	97	Missense	distal	4	no	10.215	10.221	EPSD	ICGC;COSMIC	8.283	Up-regulation
Atypical_PIKK_DNAPK_PRKDC_ST	Q8TCS8	PNPT1	P78527	PRKDC	S339	Y334C	334	Missense	distal	-5	no	9.342	9.230	EPSD	ICGC;COSMIC	8.283	Down-regulation
Atypical_PIKK_DNAPK_PRKDC_ST	P11387	TOP1	P78527	PRKDC	S10	A14T	14	Missense	distal	4	no	13.022	12.961	PhosphoSitePlus	ICGC;COSMIC	8.283	Down-regulation
Atypical_PIKK_DNAPK_PRKDC_ST	P11387	TOP1	P78527	PRKDC	S10	H5Y	5	Missense	distal	-5	no	13.022	12.695	PhosphoSitePlus	ICGC;CCLE	8.283	Down-regulation
Atypical_PIKK_DNAPK_PRKDC_ST	P11387	TOP1	P78527	PRKDC	S10	R17Q	17	Missense	distal	7	no	13.022	14.293	PhosphoSitePlus	ICGC;COSMIC	8.283	Up-regulation
Atypical_PIKK_DNAPK_PRKDC_ST	P11387	TOP1	P78527	PRKDC	S112	K106E	106	Missense	distal	-6	no	11.151	11.361	EPSD	ICGC;COSMIC	8.283	Up-regulation
Atypical_PIKK_DNAPK_PRKDC_ST	P11387	TOP1	P78527	PRKDC	S112	D118Y	118	Missense	distal	6	no	11.151	11.154	EPSD	ICGC;COSMIC	8.283	Up-regulation
TKL_MLK_LZK_MAP3K12_ST	O14950	MYL12B	Q12852	MAP3K12	T19	T19A	19	Missense	central	0	yes	4.536	0.000	EPSD;PhosphoSitePlus	ICGC;COSMIC	1.313	Loss
TKL_MLK_LZK_MAP3K12_ST	O14950	MYL12B	Q12852	MAP3K12	S20	T19A	19	Missense	proximal	-1	no	4.000	4.009	PhosphoSitePlus;EPSD	ICGC;COSMIC	1.313	Up-regulation
TKL_MLK_LZK_MAP3K12_ST	O14950	MYL12B	Q12852	MAP3K12	T129	M130I	130	Missense	proximal	1	no	1.656	1.669	EPSD	ICGC	1.313	Up-regulation
TKL_MLK_LZK_MAP3K12_ST	O14950	MYL12B	Q12852	MAP3K12	T129	R124I	124	Missense	distal	-5	no	1.656	1.647	EPSD	ICGC;COSMIC	1.313	Down-regulation
TKL_MLK_LZK_MAP3K12_ST	O14950	MYL12B	Q12852	MAP3K12	T129	T129I	129	Missense	central	0	yes	1.656	0.000	EPSD	ICGC;COSMIC	1.313	Loss
AGC_PKN_PKN1_ST	P10636	MAPT	Q16512	PKN1	S64	P59Q	59	Missense	distal	-5	no	61.972	61.767	EPSD	ICGC	59.390	Down-regulation
AGC_PKN_PKN1_ST	P10636	MAPT	Q16512	PKN1	T167	P160L	160	Missense	distal	-7	no	80.887	80.928	EPSD	ICGC;COSMIC	59.390	Up-regulation
AGC_PKN_PKN1_ST	P10636	MAPT	Q16512	PKN1	T167	R164T	164	Missense	distal	-3	no	80.887	72.015	EPSD	ICGC;COSMIC	59.390	Down-regulation
AGC_PKN_PKN1_ST	P10636	MAPT	Q16512	PKN1	T167	A166T	166	Missense	proximal	-1	no	80.887	83.519	EPSD	ICGC	59.390	Up-regulation
AGC_PKN_PKN1_ST	P10636	MAPT	Q16512	PKN1	S171	R164T	164	Missense	distal	-7	no	79.050	79.169	EPSD	ICGC;COSMIC	59.390	Up-regulation
AGC_PKN_PKN1_ST	P10636	MAPT	Q16512	PKN1	S171	A166T	166	Missense	distal	-5	no	79.050	79.024	EPSD	ICGC	59.390	Down-regulation
AGC_PKN_PKN1_ST	P10636	MAPT	Q16512	PKN1	S214	G208C	208	Missense	distal	-6	no	64.058	62.815	EPSD;PhosphoSitePlus	ICGC;COSMIC	59.390	Down-regulation
AGC_PKN_PKN1_ST	P10636	MAPT	Q16512	PKN1	S214	R211S	211	Missense	distal	-3	no	64.058	49.227	EPSD;PhosphoSitePlus	ICGC;COSMIC	59.390	Loss
AGC_PKN_PKN1_ST	P10636	MAPT	Q16512	PKN1	S214	G213E	213	Missense	proximal	-1	no	64.058	66.481	EPSD;PhosphoSitePlus	ICGC;COSMIC	59.390	Up-regulation
AGC_PKN_PKN1_ST	P10636	MAPT	Q16512	PKN1	S369	R364W	364	Missense	distal	-5	no	64.889	64.133	EPSD	ICGC;COSMIC	59.390	Down-regulation
AGC_PKN_PKN1_ST	P10636	MAPT	Q16512	PKN1	S369	P363L	363	Missense	distal	-6	no	64.889	64.406	EPSD	ICGC	59.390	Down-regulation
AGC_PKN_PKN1_ST	P10636	MAPT	Q16512	PKN1	S515	G521R	521	Missense	distal	6	no	68.334	69.055	EPSD	ICGC;COSMIC	59.390	Up-regulation
AGC_PKN_PKN1_ST	P10636	MAPT	Q16512	PKN1	S525	G521R	521	Missense	distal	-4	no	66.199	67.435	EPSD	ICGC;COSMIC	59.390	Up-regulation
AGC_PKN_PKN1_ST	P00533	EGFR	Q16512	PKN1	S1162	A1155T	1155	Missense	distal	-7	no	60.254	60.287	EPSD	ICGC	59.390	Up-regulation
AGC_PKN_PKN1_ST	P00533	EGFR	Q16512	PKN1	S1162	D1168N	1168	Missense	distal	6	no	60.254	61.301	EPSD	ICGC;COSMIC	59.390	Up-regulation
AGC_PKN_PKN1_ST	P00533	EGFR	Q16512	PKN1	S1162	H1156N	1156	Missense	distal	-6	no	60.254	61.605	EPSD	ICGC;COSMIC	59.390	Up-regulation
AGC_PKN_PKN1_ST	P00533	EGFR	Q16512	PKN1	S1162	N1169S	1169	Missense	distal	7	no	60.254	60.762	EPSD	ICGC	59.390	Up-regulation
AGC_PKN_PKN1_ST	P00533	EGFR	Q16512	PKN1	S1162	Q1164R	1164	Missense	proximal	2	no	60.254	61.743	EPSD	ICGC;COSMIC	59.390	Up-regulation
AGC_PKN_PKN1_ST	P00533	EGFR	Q16512	PKN1	S1166	D1168N	1168	Missense	proximal	2	no	58.373	62.398	EPSD	ICGC;COSMIC	59.390	Gain
AGC_PKN_PKN1_ST	P00533	EGFR	Q16512	PKN1	S1166	Q1164R	1164	Missense	proximal	-2	no	58.373	63.729	EPSD	ICGC;COSMIC	59.390	Gain
AGC_PKN_PKN1_ST	Q9UKV0	HDAC9	Q16512	PKN1	S240	S240N	240	Missense	central	0	yes	73.557	0.000	EPSD	ICGC	59.390	Loss
AGC_PKN_PKN1_ST	Q9UKV0	HDAC9	Q16512	PKN1	S611	P613S	613	Missense	proximal	2	no	64.406	64.519	EPSD	ICGC;COSMIC;CCLE	59.390	Up-regulation
AGC_PKN_PKN1_ST	Q9UKV0	HDAC9	Q16512	PKN1	S611	S612F	612	Missense	proximal	1	no	64.406	81.017	EPSD	ICGC;COSMIC	59.390	Up-regulation
AGC_PKN_PKN1_ST	Q9UKV0	HDAC9	Q16512	PKN1	S611	A614T	614	Missense	distal	3	no	64.406	64.893	EPSD	ICGC;COSMIC	59.390	Up-regulation
AGC_PKN_PKN1_ST	Q9UKV0	HDAC9	Q16512	PKN1	S611	R604H	604	Missense	distal	-7	no	64.406	64.477	EPSD	ICGC;COSMIC	59.390	Up-regulation
AGC_PKN_PKN1_ST	Q9UKV0	HDAC9	Q16512	PKN1	S611	T609S	609	Missense	proximal	-2	no	64.406	69.713	EPSD	ICGC	59.390	Up-regulation
AGC_PKN_PKN1_ST	Q9UKV0	HDAC9	Q16512	PKN1	S663	R660Q	660	Missense	distal	-3	no	60.191	50.509	EPSD	ICGC;COSMIC	59.390	Loss
AGC_PKN_PKN1_ST	Q9UKV0	HDAC9	Q16512	PKN1	S663	R667Q	667	Missense	distal	4	no	60.191	58.871	EPSD	ICGC;COSMIC	59.390	Loss
AGC_PKN_PKN1_ST	Q9UKV0	HDAC9	Q16512	PKN1	S663	H657R	657	Missense	distal	-6	no	60.191	60.642	EPSD	ICGC;COSMIC	59.390	Up-regulation
AGC_PKN_PKN1_ST	Q9UKV0	HDAC9	Q16512	PKN1	S663	E670K	670	Missense	distal	7	no	60.191	59.645	EPSD	ICGC;COSMIC	59.390	Down-regulation
AGC_PKN_PKN1_ST	Q9UKV0	HDAC9	Q16512	PKN1	S663	R667L	667	Missense	distal	4	no	60.191	53.586	EPSD	ICGC;COSMIC	59.390	Loss
AGC_PKN_PKN1_ST	Q9UQL6	HDAC5	Q16512	PKN1	S224	S225R	225	Missense	proximal	1	no	54.895	64.908	EPSD	ICGC;COSMIC	59.390	Gain
AGC_PKN_PKN1_ST	O15553	MEFV	Q16512	PKN1	S141	G138R	138	Missense	distal	-3	no	25.710	77.594	EPSD	ICGC;COSMIC	59.390	Gain
AGC_PKN_PKN1_ST	O15553	MEFV	Q16512	PKN1	S179	R176W	176	Missense	distal	-3	no	69.033	27.601	EPSD	ICGC;COSMIC	59.390	Loss
AGC_PKN_PKN1_ST	O15553	MEFV	Q16512	PKN1	S208	R202Q	202	Missense	distal	-6	no	89.788	89.409	PhosphoSitePlus;EPSD	ICGC;COSMIC	59.390	Down-regulation
AGC_PKN_PKN1_ST	O15553	MEFV	Q16512	PKN1	S208	R202W	202	Missense	distal	-6	no	89.788	89.316	PhosphoSitePlus;EPSD	ICGC;COSMIC	59.390	Down-regulation
AGC_PKN_PKN1_ST	O15553	MEFV	Q16512	PKN1	S208	A210T	210	Missense	proximal	2	no	89.788	88.891	PhosphoSitePlus;EPSD	ICGC;COSMIC	59.390	Down-regulation
AGC_PKN_PKN1_ST	O15553	MEFV	Q16512	PKN1	S208	R204C	204	Missense	distal	-4	no	89.788	83.756	PhosphoSitePlus;EPSD	ICGC;COSMIC	59.390	Down-regulation
AGC_PKN_PKN1_ST	P30622	CLIP1	Q16512	PKN1	T27	T25K	25	Missense	proximal	-2	no	60.772	60.354	EPSD	ICGC	59.390	Down-regulation
AGC_PKN_PKN1_ST	P30622	CLIP1	Q16512	PKN1	S180	S186N	186	Missense	distal	6	no	58.830	59.743	EPSD	ICGC;COSMIC	59.390	Gain
AGC_PKN_PKN1_ST	P30622	CLIP1	Q16512	PKN1	S180	E178D	178	Missense	proximal	-2	no	58.830	67.728	EPSD	ICGC;COSMIC	59.390	Gain
AGC_PKN_PKN1_ST	P30622	CLIP1	Q16512	PKN1	S186	S193N	193	Missense	distal	7	no	60.580	60.072	EPSD	ICGC;COSMIC	59.390	Down-regulation
AGC_PKN_PKN1_ST	P30622	CLIP1	Q16512	PKN1	S186	S186N	186	Missense	central	0	yes	60.580	0.000	EPSD	ICGC;COSMIC	59.390	Loss
AGC_PKN_PKN1_ST	P30622	CLIP1	Q16512	PKN1	S312	S314P	314	Missense	proximal	2	no	88.259	88.146	PhosphoSitePlus	ICGC;COSMIC	59.390	Down-regulation
AGC_PKN_PKN1_ST	P30622	CLIP1	Q16512	PKN1	S320	S314P	314	Missense	distal	-6	no	68.123	68.144	EPSD	ICGC;COSMIC	59.390	Up-regulation
AGC_PKN_PKN1_ST	P30622	CLIP1	Q16512	PKN1	S328	L335R	335	Missense	distal	7	no	62.490	62.778	EPSD	ICGC;COSMIC	59.390	Up-regulation
AGC_PKN_PKN1_ST	P30622	CLIP1	Q16512	PKN1	S331	L335R	335	Missense	distal	4	no	62.196	68.801	EPSD	ICGC;COSMIC	59.390	Up-regulation
AGC_PKN_PKN1_ST	P30622	CLIP1	Q16512	PKN1	T1036	T1038I	1038	Missense	proximal	2	no	68.162	69.168	EPSD	ICGC	59.390	Up-regulation
AGC_PKN_PKN1_ST	Q16512	PKN1	Q16512	PKN1	T64	R61W	61	Missense	distal	-3	no	81.694	40.261	EPSD	ICGC;COSMIC	59.390	Loss
AGC_PKN_PKN1_ST	Q16512	PKN1	Q16512	PKN1	S81	R78W	78	Missense	distal	-3	no	72.999	31.567	EPSD	ICGC;COSMIC	59.390	Loss
AGC_PKN_PKN1_ST	Q16512	PKN1	Q16512	PKN1	S81	E74D	74	Missense	distal	-7	no	72.999	72.794	EPSD	ICGC;COSMIC	59.390	Down-regulation
AGC_PKN_PKN1_ST	Q16512	PKN1	Q16512	PKN1	T123	C120F	120	Missense	distal	-3	no	1.086	61.115	EPSD	ICGC	59.390	Gain
AGC_PKN_PKN1_ST	Q16512	PKN1	Q16512	PKN1	S126	C120F	120	Missense	distal	-6	no	68.591	69.942	EPSD	ICGC	59.390	Up-regulation
AGC_PKN_PKN1_ST	Q16512	PKN1	Q16512	PKN1	S126	V128M	128	Missense	proximal	2	no	68.591	69.996	EPSD	ICGC;COSMIC	59.390	Up-regulation
AGC_PKN_PKN1_ST	Q16512	PKN1	Q16512	PKN1	S126	R127C	127	Missense	proximal	1	no	68.591	66.875	EPSD	ICGC;COSMIC	59.390	Down-regulation
AGC_PKN_PKN1_ST	Q16512	PKN1	Q16512	PKN1	S240	A242T	242	Missense	proximal	2	no	62.490	61.593	EPSD	ICGC;COSMIC	59.390	Down-regulation
AGC_PKN_PKN1_ST	Q16512	PKN1	Q16512	PKN1	S240	K243N	243	Missense	distal	3	no	62.490	60.947	EPSD	ICGC	59.390	Down-regulation
AGC_PKN_PKN1_ST	Q16512	PKN1	Q16512	PKN1	S374	S380R	380	Missense	distal	6	no	88.259	88.921	EPSD	ICGC;COSMIC	59.390	Up-regulation
AGC_PKN_PKN1_ST	Q16512	PKN1	Q16512	PKN1	T529	F532V	532	Missense	distal	3	no	67.940	66.951	EPSD	ICGC;COSMIC	59.390	Down-regulation
AGC_PKN_PKN1_ST	Q16512	PKN1	Q16512	PKN1	T529	G530C	530	Missense	proximal	1	no	67.940	65.292	EPSD	ICGC;COSMIC	59.390	Down-regulation
AGC_PKN_PKN1_ST	Q16512	PKN1	Q16512	PKN1	T529	T531I	531	Missense	proximal	2	no	67.940	68.946	EPSD	ICGC;COSMIC	59.390	Up-regulation
AGC_PKN_PKN1_ST	Q16512	PKN1	Q16512	PKN1	T545	R543Q	543	Missense	proximal	-2	no	71.987	66.631	EPSD	ICGC;COSMIC	59.390	Down-regulation
AGC_PKN_PKN1_ST	Q16512	PKN1	Q16512	PKN1	T545	R543W	543	Missense	proximal	-2	no	71.987	59.525	EPSD	ICGC;COSMIC	59.390	Down-regulation
AGC_PKN_PKN1_ST	Q16512	PKN1	Q16512	PKN1	S578	S579F	579	Missense	proximal	1	no	50.930	67.542	EPSD	ICGC;COSMIC	59.390	Gain
AGC_PKN_PKN1_ST	Q16512	PKN1	Q16512	PKN1	T596	S603I	603	Missense	distal	7	no	74.034	73.632	EPSD	ICGC;COSMIC	59.390	Down-regulation
AGC_PKN_PKN1_ST	Q16512	PKN1	Q16512	PKN1	T596	S591L	591	Missense	distal	-5	no	74.034	74.883	EPSD	ICGC;COSMIC	59.390	Up-regulation
AGC_PKN_PKN1_ST	Q16512	PKN1	Q16512	PKN1	T596	P590L	590	Missense	distal	-6	no	74.034	73.550	EPSD	ICGC	59.390	Down-regulation
AGC_PKN_PKN1_ST	Q16512	PKN1	Q16512	PKN1	T774	T778A	778	Missense	distal	4	no	95.095	96.566	PhosphoSitePlus	ICGC;COSMIC	59.390	Up-regulation
AGC_PKN_PKN1_ST	Q16512	PKN1	Q16512	PKN1	T774	P779L	779	Missense	distal	5	no	95.095	95.333	PhosphoSitePlus	ICGC;COSMIC	59.390	Up-regulation
AGC_PKN_PKN1_ST	Q16512	PKN1	Q16512	PKN1	T774	R771Q	771	Missense	distal	-3	no	95.095	85.413	PhosphoSitePlus	ICGC;COSMIC;CCLE	59.390	Down-regulation
AGC_PKN_PKN1_ST	Q16512	PKN1	Q16512	PKN1	T774	E780K	780	Missense	distal	6	no	95.095	95.801	PhosphoSitePlus	ICGC;COSMIC	59.390	Up-regulation
AGC_PKN_PKN1_ST	Q16512	PKN1	Q16512	PKN1	T774	R771W	771	Missense	distal	-3	no	95.095	53.663	PhosphoSitePlus	ICGC	59.390	Loss
AGC_PKN_PKN1_ST	Q16512	PKN1	Q16512	PKN1	T774	P779Q	779	Missense	distal	5	no	95.095	95.122	PhosphoSitePlus	ICGC;COSMIC	59.390	Up-regulation
AGC_PKN_PKN1_ST	Q16512	PKN1	Q16512	PKN1	T899	T894M	894	Missense	distal	-5	no	64.664	64.944	EPSD	ICGC;COSMIC	59.390	Up-regulation
AGC_PKN_PKN1_ST	Q16512	PKN1	Q16512	PKN1	T899	V901I	901	Missense	proximal	2	no	64.664	66.201	EPSD	ICGC;COSMIC	59.390	Up-regulation
AGC_PKN_PKN1_ST	Q16512	PKN1	Q16512	PKN1	T899	P893L	893	Missense	distal	-6	no	64.664	64.180	EPSD	ICGC	59.390	Down-regulation
AGC_PKN_PKN1_ST	Q16512	PKN1	Q16512	PKN1	T899	G897D	897	Missense	proximal	-2	no	64.664	63.983	EPSD	ICGC	59.390	Down-regulation
Atypical_PIKK_SMG1_SMG1_ST	Q92900	UPF1	Q96Q15	SMG1	S10	S9I	9	Missense	proximal	-1	no	2.923	3.336	EPSD	ICGC	1.372	Up-regulation
Atypical_PIKK_SMG1_SMG1_ST	Q92900	UPF1	Q96Q15	SMG1	S42	Q43K	43	Missense	proximal	1	no	2.743	-0.154	EPSD	ICGC;COSMIC	1.372	Loss
Atypical_PIKK_SMG1_SMG1_ST	Q92900	UPF1	Q96Q15	SMG1	S42	P48H	48	Missense	distal	6	no	2.743	2.758	EPSD	ICGC;COSMIC	1.372	Up-regulation
Atypical_PIKK_SMG1_SMG1_ST	Q92900	UPF1	Q96Q15	SMG1	T44	Q43K	43	Missense	proximal	-1	no	3.393	3.661	EPSD	ICGC;COSMIC	1.372	Up-regulation
Atypical_PIKK_SMG1_SMG1_ST	Q92900	UPF1	Q96Q15	SMG1	T44	P48H	48	Missense	distal	4	no	3.393	3.344	EPSD	ICGC;COSMIC	1.372	Down-regulation
Atypical_PIKK_SMG1_SMG1_ST	Q92900	UPF1	Q96Q15	SMG1	S215	K220N	220	Missense	distal	5	no	3.393	3.394	EPSD	ICGC	1.372	Up-regulation
Atypical_PIKK_SMG1_SMG1_ST	Q92900	UPF1	Q96Q15	SMG1	T429	S428L	428	Missense	proximal	-1	no	0.347	1.820	EPSD	ICGC;COSMIC	1.372	Gain
Atypical_PIKK_SMG1_SMG1_ST	Q92900	UPF1	Q96Q15	SMG1	S599	R605L	605	Missense	distal	6	no	1.949	1.919	EPSD	ICGC;COSMIC	1.372	Down-regulation
Atypical_PIKK_SMG1_SMG1_ST	Q92900	UPF1	Q96Q15	SMG1	S692	L695P	695	Missense	distal	3	no	3.881	4.060	EPSD	ICGC;COSMIC	1.372	Up-regulation
Atypical_PIKK_SMG1_SMG1_ST	Q92900	UPF1	Q96Q15	SMG1	S692	G690W	690	Missense	proximal	-2	no	3.881	3.867	EPSD	ICGC	1.372	Down-regulation
Atypical_PIKK_SMG1_SMG1_ST	Q92900	UPF1	Q96Q15	SMG1	S692	A686V	686	Missense	distal	-6	no	3.881	3.891	EPSD	ICGC;COSMIC	1.372	Up-regulation
Atypical_PIKK_SMG1_SMG1_ST	Q92900	UPF1	Q96Q15	SMG1	S1084	L1083I	1083	Missense	proximal	-1	no	6.300	5.239	EPSD;PhosphoSitePlus	ICGC;COSMIC;GDSC	1.372	Down-regulation
Atypical_PIKK_SMG1_SMG1_ST	Q92900	UPF1	Q96Q15	SMG1	S1084	P1086L	1086	Missense	proximal	2	no	6.300	6.315	EPSD;PhosphoSitePlus	ICGC;COSMIC	1.372	Up-regulation
Atypical_PIKK_SMG1_SMG1_ST	Q92900	UPF1	Q96Q15	SMG1	S1089	L1083I	1083	Missense	distal	-6	no	5.994	5.995	EPSD;PhosphoSitePlus	ICGC;COSMIC;GDSC	1.372	Up-regulation
Atypical_PIKK_SMG1_SMG1_ST	Q92900	UPF1	Q96Q15	SMG1	S1089	P1086L	1086	Missense	distal	-3	no	5.994	5.577	EPSD;PhosphoSitePlus	ICGC;COSMIC	1.372	Down-regulation
Atypical_PIKK_SMG1_SMG1_ST	Q92900	UPF1	Q96Q15	SMG1	S1127	V1123G	1123	Missense	distal	-4	no	4.310	4.311	EPSD;PhosphoSitePlus	ICGC	1.372	Up-regulation
Atypical_PIKK_SMG1_SMG1_ST	Q92900	UPF1	Q96Q15	SMG1	S1127	G1122R	1122	Missense	distal	-5	no	4.310	4.302	EPSD;PhosphoSitePlus	ICGC;COSMIC	1.372	Down-regulation
Atypical_PIKK_SMG1_SMG1_ST	P04637	TP53	Q96Q15	SMG1	S15	E11K	11	Missense	distal	-4	no	5.075	5.074	PhosphoSitePlus	ICGC;COSMIC	1.372	Down-regulation
Atypical_PIKK_SMG1_SMG1_ST	P04637	TP53	Q96Q15	SMG1	S33	P34L	34	Missense	proximal	1	no	1.652	1.893	EPSD	ICGC;COSMIC	1.372	Up-regulation
Atypical_PIKK_SMG1_SMG1_ST	P04637	TP53	Q96Q15	SMG1	S33	S33F	33	Missense	central	0	yes	1.652	0.000	EPSD	ICGC;COSMIC	1.372	Loss
Atypical_PIKK_SMG1_SMG1_ST	P04637	TP53	Q96Q15	SMG1	S33	N30I	30	Missense	distal	-3	no	1.652	1.635	EPSD	ICGC	1.372	Down-regulation
Atypical_PIKK_SMG1_SMG1_ST	P04637	TP53	Q96Q15	SMG1	S37	P34L	34	Missense	distal	-3	no	2.919	2.502	EPSD	ICGC;COSMIC	1.372	Down-regulation
Atypical_PIKK_SMG1_SMG1_ST	P04637	TP53	Q96Q15	SMG1	S37	S33F	33	Missense	distal	-4	no	2.919	2.921	EPSD	ICGC;COSMIC	1.372	Up-regulation
Atypical_PIKK_SMG1_SMG1_ST	P04637	TP53	Q96Q15	SMG1	S37	N30I	30	Missense	distal	-7	no	2.919	2.914	EPSD	ICGC	1.372	Down-regulation
Atypical_PIKK_SMG1_SMG1_ST	P04637	TP53	Q96Q15	SMG1	S99	Q100K	100	Missense	proximal	1	no	3.102	0.205	EPSD	ICGC;COSMIC	1.372	Loss
Atypical_PIKK_SMG1_SMG1_ST	P04637	TP53	Q96Q15	SMG1	S99	P92T	92	Missense	distal	-7	no	3.102	3.071	EPSD	ICGC;COSMIC	1.372	Down-regulation
Atypical_PIKK_SMG1_SMG1_ST	P04637	TP53	Q96Q15	SMG1	S99	P92H	92	Missense	distal	-7	no	3.102	3.111	EPSD	ICGC;COSMIC	1.372	Up-regulation
Atypical_PIKK_SMG1_SMG1_ST	P04637	TP53	Q96Q15	SMG1	S99	G105A	105	Missense	distal	6	no	3.102	3.120	EPSD	ICGC;COSMIC	1.372	Up-regulation
STE_STE11_ASK_MAP3K6_ST	P45983	MAPK8	O95382	MAP3K6	T19	R25L	25	Missense	distal	6	no	4.888	4.217	EPSD	ICGC	1.891	Down-regulation
STE_STE11_ASK_MAP3K6_ST	P45983	MAPK8	O95382	MAP3K6	T19	E14D	14	Missense	distal	-5	no	4.888	5.312	EPSD	ICGC	1.891	Up-regulation
STE_STE11_ASK_MAP3K6_ST	P45983	MAPK8	O95382	MAP3K6	T19	R25Q	25	Missense	distal	6	no	4.888	4.803	EPSD	ICGC;COSMIC	1.891	Down-regulation
STE_STE11_ASK_MAP3K6_ST	P45983	MAPK8	O95382	MAP3K6	T19	Y26C	26	Missense	distal	7	no	4.888	2.805	EPSD	ICGC	1.891	Down-regulation
STE_STE11_ASK_MAP3K6_ST	P45983	MAPK8	O95382	MAP3K6	T178	S179I	179	Missense	proximal	1	no	1.978	2.150	EPSD	ICGC	1.891	Up-regulation
STE_STE11_ASK_MAP3K6_ST	P45983	MAPK8	O95382	MAP3K6	T178	G171C	171	Missense	distal	-7	no	1.978	1.923	EPSD	ICGC;COSMIC	1.891	Down-regulation
STE_STE11_ASK_MAP3K6_ST	P45983	MAPK8	O95382	MAP3K6	T178	T183M	183	Missense	distal	5	no	1.978	1.362	EPSD	ICGC;COSMIC	1.891	Loss
STE_STE11_ASK_MAP3K6_ST	P45983	MAPK8	O95382	MAP3K6	T183	R189P	189	Missense	distal	6	no	15.332	14.507	PhosphoSitePlus;EPSD	ICGC;COSMIC	1.891	Down-regulation
STE_STE11_ASK_MAP3K6_ST	P45983	MAPK8	O95382	MAP3K6	T183	S179I	179	Missense	distal	-4	no	15.332	15.233	PhosphoSitePlus;EPSD	ICGC	1.891	Down-regulation
STE_STE11_ASK_MAP3K6_ST	P45983	MAPK8	O95382	MAP3K6	T183	T183M	183	Missense	central	0	yes	15.332	0.000	PhosphoSitePlus;EPSD	ICGC;COSMIC	1.891	Loss
STE_STE11_ASK_MAP3K6_ST	P45983	MAPK8	O95382	MAP3K6	T188	R189P	189	Missense	proximal	1	no	1.928	1.987	EPSD	ICGC;COSMIC	1.891	Up-regulation
STE_STE11_ASK_MAP3K6_ST	P45983	MAPK8	O95382	MAP3K6	T188	T183M	183	Missense	distal	-5	no	1.928	-0.446	EPSD	ICGC;COSMIC	1.891	Loss
STE_STE11_ASK_MAP3K6_ST	O95382	MAP3K6	O95382	MAP3K6	T793	F791C	791	Missense	proximal	-2	no	2.019	2.013	EPSD	ICGC;COSMIC	1.891	Down-regulation
STE_STE11_ASK_MAP3K6_ST	O95382	MAP3K6	O95382	MAP3K6	S938	N937K	937	Missense	proximal	-1	no	2.245	2.230	EPSD	ICGC	1.891	Down-regulation
STE_STE11_ASK_MAP3K6_ST	O95382	MAP3K6	O95382	MAP3K6	S938	Q941K	941	Missense	distal	3	no	2.245	2.244	EPSD	ICGC	1.891	Down-regulation
STE_STE11_ASK_MAP3K6_ST	O95382	MAP3K6	O95382	MAP3K6	S938	P932H	932	Missense	distal	-6	no	2.245	2.233	EPSD	ICGC	1.891	Down-regulation
STE_STE11_ASK_MAP3K6_ST	O95382	MAP3K6	O95382	MAP3K6	T944	N937K	937	Missense	distal	-7	no	3.665	3.602	EPSD	ICGC	1.891	Down-regulation
STE_STE11_ASK_MAP3K6_ST	O95382	MAP3K6	O95382	MAP3K6	T944	Q941K	941	Missense	distal	-3	no	3.665	3.651	EPSD	ICGC	1.891	Down-regulation
CAMK_DAPK_DAPK_DAPK1_ST	P53355	DAPK1	P53355	DAPK1	S57	R53W	53	Missense	distal	-4	no	10.150	10.057	EPSD	ICGC;COSMIC	8.849	Down-regulation
CAMK_DAPK_DAPK_DAPK1_ST	P53355	DAPK1	P53355	DAPK1	S57	R63L	63	Missense	distal	6	no	10.150	10.357	EPSD	ICGC;COSMIC	8.849	Up-regulation
CAMK_DAPK_DAPK_DAPK1_ST	P53355	DAPK1	P53355	DAPK1	S57	R54L	54	Missense	distal	-3	no	10.150	5.063	EPSD	ICGC;COSMIC;GDSC;CCLE	8.849	Loss
CAMK_DAPK_DAPK_DAPK1_ST	P53355	DAPK1	P53355	DAPK1	S308	A301V	301	Missense	distal	-7	no	14.981	14.217	PhosphoSitePlus	ICGC;COSMIC	8.849	Down-regulation
CAMK_DAPK_DAPK_DAPK1_ST	P53355	DAPK1	P53355	DAPK1	S308	S308F	308	Missense	central	0	yes	14.981	0.000	PhosphoSitePlus	ICGC;COSMIC	8.849	Loss
CAMK_DAPK_DAPK_DAPK1_ST	P53355	DAPK1	P53355	DAPK1	S313	R317G	317	Missense	distal	4	no	15.405	15.122	EPSD	ICGC;COSMIC	8.849	Down-regulation
CAMK_DAPK_DAPK_DAPK1_ST	P53355	DAPK1	P53355	DAPK1	S313	S308F	308	Missense	distal	-5	no	15.405	15.281	EPSD	ICGC;COSMIC	8.849	Down-regulation
CAMK_DAPK_DAPK_DAPK1_ST	P53355	DAPK1	P53355	DAPK1	S319	S321L	321	Missense	proximal	2	no	11.303	11.335	EPSD	ICGC;COSMIC	8.849	Up-regulation
CAMK_DAPK_DAPK_DAPK1_ST	P53355	DAPK1	P53355	DAPK1	S319	R317G	317	Missense	proximal	-2	no	11.303	8.402	EPSD	ICGC;COSMIC	8.849	Loss
CAMK_DAPK_DAPK_DAPK1_ST	P53355	DAPK1	P53355	DAPK1	S635	L639R	639	Missense	distal	4	no	11.113	10.518	EPSD	ICGC;COSMIC	8.849	Down-regulation
CAMK_DAPK_DAPK_DAPK1_ST	P53355	DAPK1	P53355	DAPK1	S635	V636F	636	Missense	proximal	1	no	11.113	11.529	EPSD	ICGC;COSMIC	8.849	Up-regulation
CAMK_DAPK_DAPK_DAPK1_ST	P53355	DAPK1	P53355	DAPK1	S762	E766K	766	Missense	distal	4	no	9.106	9.937	EPSD	ICGC;COSMIC	8.849	Up-regulation
CAMK_DAPK_DAPK_DAPK1_ST	P53355	DAPK1	P53355	DAPK1	S762	S757I	757	Missense	distal	-5	no	9.106	8.819	EPSD	ICGC	8.849	Loss
CAMK_DAPK_DAPK_DAPK1_ST	P53355	DAPK1	P53355	DAPK1	S762	V758A	758	Missense	distal	-4	no	9.106	9.135	EPSD	ICGC;COSMIC	8.849	Up-regulation
CAMK_DAPK_DAPK_DAPK1_ST	P53355	DAPK1	P53355	DAPK1	S762	R759K	759	Missense	distal	-3	no	9.106	7.743	EPSD	ICGC	8.849	Loss
CAMK_DAPK_DAPK_DAPK1_ST	P53355	DAPK1	P53355	DAPK1	S1425	G1418C	1418	Missense	distal	-7	no	7.548	8.986	EPSD	ICGC;COSMIC	8.849	Gain
CAMK_DAPK_DAPK_DAPK1_ST	Q96RR4	CAMKK2	P53355	DAPK1	T145	V151I	151	Missense	distal	6	no	9.938	11.626	EPSD	ICGC;CCLE	8.849	Up-regulation
CAMK_DAPK_DAPK_DAPK1_ST	Q96RR4	CAMKK2	P53355	DAPK1	T145	P144S	144	Missense	proximal	-1	no	9.938	10.976	EPSD	ICGC;COSMIC	8.849	Up-regulation
CAMK_DAPK_DAPK_DAPK1_ST	Q96RR4	CAMKK2	P53355	DAPK1	T350	T347S	347	Missense	distal	-3	no	9.990	9.348	EPSD	ICGC;COSMIC	8.849	Down-regulation
CAMK_DAPK_DAPK_DAPK1_ST	Q96RR4	CAMKK2	P53355	DAPK1	T350	F353L	353	Missense	distal	3	no	9.990	9.472	EPSD	ICGC	8.849	Down-regulation
CAMK_DAPK_DAPK_DAPK1_ST	Q96RR4	CAMKK2	P53355	DAPK1	T350	T347N	347	Missense	distal	-3	no	9.990	8.920	EPSD	ICGC	8.849	Down-regulation
CAMK_DAPK_DAPK_DAPK1_ST	Q96RR4	CAMKK2	P53355	DAPK1	T350	A352T	352	Missense	proximal	2	no	9.990	10.283	EPSD	ICGC	8.849	Up-regulation
CAMK_DAPK_DAPK_DAPK1_ST	Q96RR4	CAMKK2	P53355	DAPK1	S509	R508H	508	Missense	proximal	-1	no	9.171	9.290	EPSD	ICGC	8.849	Up-regulation
CAMK_DAPK_DAPK_DAPK1_ST	Q96RR4	CAMKK2	P53355	DAPK1	S511	T518N	518	Missense	distal	7	no	15.718	15.800	PhosphoSitePlus	ICGC	8.849	Up-regulation
CAMK_DAPK_DAPK_DAPK1_ST	Q96RR4	CAMKK2	P53355	DAPK1	S511	R508H	508	Missense	distal	-3	no	15.718	11.088	PhosphoSitePlus	ICGC	8.849	Down-regulation
CAMK_DAPK_DAPK_DAPK1_ST	Q96RR4	CAMKK2	P53355	DAPK1	T518	K520T	520	Missense	proximal	2	no	9.782	9.958	EPSD	ICGC	8.849	Up-regulation
CAMK_DAPK_DAPK_DAPK1_ST	Q96RR4	CAMKK2	P53355	DAPK1	T518	T518N	518	Missense	central	0	yes	9.782	0.000	EPSD	ICGC	8.849	Loss
CAMK_DAPK_DAPK_DAPK1_ST	Q96RR4	CAMKK2	P53355	DAPK1	T522	K520T	520	Missense	proximal	-2	no	9.295	7.574	EPSD	ICGC	8.849	Loss
CAMK_DAPK_DAPK_DAPK1_ST	Q96RR4	CAMKK2	P53355	DAPK1	T522	T518N	518	Missense	distal	-4	no	9.295	9.235	EPSD	ICGC	8.849	Down-regulation
CAMK_DAPK_DAPK_DAPK1_ST	Q00613	HSF1	P53355	DAPK1	T142	L146R	146	Missense	distal	4	no	9.088	8.493	EPSD	ICGC	8.849	Loss
CAMK_DAPK_DAPK_DAPK1_ST	Q00613	HSF1	P53355	DAPK1	S216	P223L	223	Missense	distal	7	no	9.469	10.699	EPSD	ICGC	8.849	Up-regulation
CAMK_DAPK_DAPK_DAPK1_ST	Q00613	HSF1	P53355	DAPK1	S216	M212V	212	Missense	distal	-4	no	9.469	9.214	EPSD	ICGC	8.849	Down-regulation
CAMK_DAPK_DAPK_DAPK1_ST	Q00613	HSF1	P53355	DAPK1	S218	P223L	223	Missense	distal	5	no	10.859	10.151	EPSD	ICGC	8.849	Down-regulation
CAMK_DAPK_DAPK_DAPK1_ST	Q00613	HSF1	P53355	DAPK1	S218	M212V	212	Missense	distal	-6	no	10.859	9.597	EPSD	ICGC	8.849	Down-regulation
CAMK_DAPK_DAPK_DAPK1_ST	Q00613	HSF1	P53355	DAPK1	S230	P223L	223	Missense	distal	-7	no	15.223	15.543	PhosphoSitePlus	ICGC	8.849	Up-regulation
CAMK_DAPK_DAPK_DAPK1_ST	Q00613	HSF1	P53355	DAPK1	S279	A278T	278	Missense	proximal	-1	no	10.183	10.358	EPSD	ICGC	8.849	Up-regulation
CAMK_DAPK_DAPK_DAPK1_ST	Q00613	HSF1	P53355	DAPK1	S438	A437S	437	Missense	proximal	-1	no	10.117	10.880	EPSD	ICGC;COSMIC	8.849	Up-regulation
CAMK_DAPK_DAPK_DAPK1_ST	Q00613	HSF1	P53355	DAPK1	S438	S435N	435	Missense	distal	-3	no	10.117	9.689	EPSD	ICGC;COSMIC	8.849	Down-regulation
CAMK_DAPK_DAPK_DAPK1_ST	P40429	RPL13A	P53355	DAPK1	S67	Y71D	71	Missense	distal	4	no	10.735	10.557	EPSD	ICGC	8.849	Down-regulation
CAMK_DAPK_DAPK_DAPK1_ST	P40429	RPL13A	P53355	DAPK1	S67	P66S	66	Missense	proximal	-1	no	10.735	11.773	EPSD	ICGC;COSMIC	8.849	Up-regulation
CAMK_DAPK_DAPK_DAPK1_ST	P40429	RPL13A	P53355	DAPK1	S77	P76S	76	Missense	proximal	-1	no	16.021	17.059	PhosphoSitePlus	ICGC;COSMIC	8.849	Up-regulation
CAMK_DAPK_DAPK_DAPK1_ST	P40429	RPL13A	P53355	DAPK1	S77	Y71D	71	Missense	distal	-6	no	16.021	16.823	PhosphoSitePlus	ICGC	8.849	Up-regulation
CAMK_DAPK_DAPK_DAPK1_ST	O14950	MYL12B	P53355	DAPK1	S20	T19A	19	Missense	proximal	-1	no	13.300	13.125	PhosphoSitePlus	ICGC;COSMIC	8.849	Down-regulation
CAMK_DAPK_DAPK_DAPK1_ST	O14950	MYL12B	P53355	DAPK1	T135	M130I	130	Missense	distal	-5	no	9.119	8.884	EPSD	ICGC	8.849	Down-regulation
CAMK_DAPK_DAPK_DAPK1_ST	O14950	MYL12B	P53355	DAPK1	T135	T129I	129	Missense	distal	-6	no	9.119	7.403	EPSD	ICGC;COSMIC	8.849	Loss
CAMK_DAPK_DAPK_DAPK1_ST	Q14457	BECN1	P53355	DAPK1	S90	P85Q	85	Missense	distal	-5	no	8.647	8.961	EPSD	ICGC	8.849	Gain
CAMK_DAPK_DAPK_DAPK1_ST	Q14457	BECN1	P53355	DAPK1	T91	P85Q	85	Missense	distal	-6	no	10.617	11.953	EPSD	ICGC	8.849	Up-regulation
CAMK_DAPK_DAPK_DAPK1_ST	Q14457	BECN1	P53355	DAPK1	S96	A103E	103	Missense	distal	7	no	9.141	8.957	EPSD	ICGC	8.849	Down-regulation
CAMK_DAPK_DAPK_DAPK1_ST	Q14457	BECN1	P53355	DAPK1	T98	D105N	105	Missense	distal	7	no	9.650	9.849	EPSD	ICGC	8.849	Up-regulation
CAMK_DAPK_DAPK_DAPK1_ST	Q14457	BECN1	P53355	DAPK1	T98	A103E	103	Missense	distal	5	no	9.650	9.756	EPSD	ICGC	8.849	Up-regulation
CAMK_DAPK_DAPK_DAPK1_ST	Q14457	BECN1	P53355	DAPK1	T119	S113R	113	Missense	distal	-6	no	15.276	15.426	PhosphoSitePlus	ICGC	8.849	Up-regulation
CAMK_DAPK_DAPK_DAPK1_ST	Q14457	BECN1	P53355	DAPK1	T119	L122I	122	Missense	distal	3	no	15.276	15.749	PhosphoSitePlus	ICGC;COSMIC	8.849	Up-regulation
CAMK_DAPK_DAPK_DAPK1_ST	Q14457	BECN1	P53355	DAPK1	S234	Q240K	240	Missense	distal	6	no	8.979	9.690	EPSD	ICGC	8.849	Up-regulation
CAMK_DAPK_DAPK_DAPK1_ST	Q14457	BECN1	P53355	DAPK1	S234	Q230H	230	Missense	distal	-4	no	8.979	9.011	EPSD	ICGC;COSMIC	8.849	Up-regulation
CAMK_DAPK_DAPK_DAPK1_ST	Q14457	BECN1	P53355	DAPK1	S295	P294H	294	Missense	proximal	-1	no	9.020	10.103	EPSD	ICGC	8.849	Up-regulation
CAMK_DAPK_DAPK_DAPK1_ST	Q14457	BECN1	P53355	DAPK1	S295	P297T	297	Missense	proximal	2	no	9.020	8.407	EPSD	ICGC	8.849	Loss
CAMK_DAPK_DAPK_DAPK1_ST	Q14457	BECN1	P53355	DAPK1	S337	G334R	334	Missense	distal	-3	no	9.714	14.361	EPSD	ICGC;COSMIC	8.849	Up-regulation
CAMK_DAPK_DAPK_DAPK1_ST	Q14457	BECN1	P53355	DAPK1	S337	S341F	341	Missense	distal	4	no	9.714	8.840	EPSD	ICGC;COSMIC	8.849	Loss
CAMK_DAPK_DAPK_DAPK1_ST	Q14457	BECN1	P53355	DAPK1	S337	P332S	332	Missense	distal	-5	no	9.714	10.100	EPSD	ICGC	8.849	Up-regulation
CAMK_DAPK_DAPK_DAPK1_ST	Q14457	BECN1	P53355	DAPK1	T417	I415M	415	Missense	proximal	-2	no	8.495	10.589	EPSD	ICGC	8.849	Gain
CAMK_DAPK_DAPK_DAPK1_ST	P04637	TP53	P53355	DAPK1	S46	D48G	48	Missense	proximal	2	no	10.502	10.479	EPSD	ICGC;COSMIC	8.849	Down-regulation
CAMK_DAPK_DAPK_DAPK1_ST	P04637	TP53	P53355	DAPK1	S46	Q52K	52	Missense	distal	6	no	10.502	11.213	EPSD	ICGC	8.849	Up-regulation
CAMK_DAPK_DAPK_DAPK1_ST	P04637	TP53	P53355	DAPK1	S127	C124R	124	Missense	distal	-3	no	5.236	10.064	EPSD	ICGC;COSMIC;GDSC;CCLE	8.849	Gain
CAMK_DAPK_DAPK_DAPK1_ST	P04637	TP53	P53355	DAPK1	S269	A276V	276	Missense	distal	7	no	15.697	15.899	EPSD;PhosphoSitePlus	ICGC;COSMIC	8.849	Up-regulation
CAMK_DAPK_DAPK_DAPK1_ST	P04637	TP53	P53355	DAPK1	S269	V274A	274	Missense	distal	5	no	15.697	15.446	EPSD;PhosphoSitePlus	ICGC;COSMIC	8.849	Down-regulation
CAMK_DAPK_DAPK_DAPK1_ST	P04637	TP53	P53355	DAPK1	S269	V272E	272	Missense	distal	3	no	15.697	14.962	EPSD;PhosphoSitePlus	ICGC;COSMIC;CCLE	8.849	Down-regulation
CAMK_DAPK_DAPK_DAPK1_ST	P04637	TP53	P53355	DAPK1	S269	L265T	265	Missense	distal	-4	no	15.697	15.908	EPSD;PhosphoSitePlus	ICGC	8.849	Up-regulation
CAMK_DAPK_DAPK_DAPK1_ST	P04637	TP53	P53355	DAPK1	S269	N268I	268	Missense	proximal	-1	no	15.697	15.186	EPSD;PhosphoSitePlus	ICGC;COSMIC;GDSC;CCLE	8.849	Down-regulation
CAMK_DAPK_DAPK_DAPK1_ST	P04637	TP53	P53355	DAPK1	S269	E271D	271	Missense	proximal	2	no	15.697	15.404	EPSD;PhosphoSitePlus	ICGC;COSMIC	8.849	Down-regulation
CAMK_DAPK_DAPK_DAPK1_ST	P04637	TP53	P53355	DAPK1	T304	P301T	301	Missense	distal	-3	no	6.984	10.047	EPSD	ICGC;COSMIC	8.849	Gain
CAMK_DAPK_DAPK_DAPK1_ST	P04637	TP53	P53355	DAPK1	S371	T377P	377	Missense	distal	6	no	8.890	8.327	EPSD	ICGC;COSMIC	8.849	Loss
CAMK_DAPK_DAPK_DAPK1_ST	P04637	TP53	P53355	DAPK1	S371	G374C	374	Missense	distal	3	no	8.890	8.812	EPSD	ICGC;COSMIC	8.849	Loss
CAMK_DAPK_DAPK_DAPK1_ST	P04637	TP53	P53355	DAPK1	S376	T377P	377	Missense	proximal	1	no	9.368	9.732	EPSD	ICGC;COSMIC	8.849	Up-regulation
CAMK_DAPK_DAPK_DAPK1_ST	P04637	TP53	P53355	DAPK1	S376	G374C	374	Missense	proximal	-2	no	9.368	8.293	EPSD	ICGC;COSMIC	8.849	Loss
CAMK_DAPK_DAPK_DAPK1_ST	P04637	TP53	P53355	DAPK1	S376	R379S	379	Missense	distal	3	no	9.368	8.333	EPSD	ICGC	8.849	Loss
CAMK_DAPK_DAPK_DAPK1_ST	P04637	TP53	P53355	DAPK1	S376	R379C	379	Missense	distal	3	no	9.368	10.569	EPSD	ICGC;COSMIC	8.849	Up-regulation
CAMK_DAPK_DAPK_DAPK1_ST	Q13526	PIN1	P53355	DAPK1	S71	E76K	76	Missense	distal	5	no	16.503	15.800	PhosphoSitePlus	ICGC	8.849	Down-regulation
CAMK_DAPK_DAPK_DAPK1_ST	Q13526	PIN1	P53355	DAPK1	S71	R69W	69	Missense	proximal	-2	no	16.503	13.851	PhosphoSitePlus	ICGC;COSMIC	8.849	Down-regulation
CAMK_DAPK_DAPK_DAPK1_ST	Q13526	PIN1	P53355	DAPK1	S111	A107T	107	Missense	distal	-4	no	9.084	9.286	EPSD	ICGC;COSMIC	8.849	Up-regulation
CAMK_DAPK_DAPK_DAPK1_ST	Q13526	PIN1	P53355	DAPK1	S111	Q109H	109	Missense	proximal	-2	no	9.084	9.552	EPSD	ICGC	8.849	Up-regulation
CAMK_DAPK_DAPK_DAPK1_ST	Q13526	PIN1	P53355	DAPK1	S114	A107T	107	Missense	distal	-7	no	9.285	8.811	EPSD	ICGC;COSMIC	8.849	Loss
CAMK_DAPK_DAPK_DAPK1_ST	Q13526	PIN1	P53355	DAPK1	S114	Q109H	109	Missense	distal	-5	no	9.285	9.115	EPSD	ICGC	8.849	Down-regulation
CAMK_DAPK_DAPK_DAPK1_ST	Q13526	PIN1	P53355	DAPK1	S147	G144W	144	Missense	distal	-3	no	7.229	9.168	EPSD	ICGC;COSMIC	8.849	Gain
CAMK_DAPK_DAPK_DAPK1_ST	P09493	TPM1	P53355	DAPK1	T108	R101H	101	Missense	distal	-7	no	10.333	12.661	EPSD	ICGC;COSMIC	8.849	Up-regulation
CAMK_DAPK_DAPK_DAPK1_ST	P09493	TPM1	P53355	DAPK1	T201	K198R	198	Missense	distal	-3	no	7.774	9.137	EPSD	ICGC;COSMIC	8.849	Gain
CAMK_DAPK_DAPK_DAPK1_ST	P09493	TPM1	P53355	DAPK1	S283	D280N	280	Missense	distal	-3	no	13.585	14.904	PhosphoSitePlus	ICGC;COSMIC	8.849	Up-regulation
CAMK_DAPK_DAPK_DAPK1_ST	Q13224	GRIN2B	P53355	DAPK1	S770	S770F	770	Missense	central	0	yes	9.388	0.000	EPSD	ICGC;COSMIC	8.849	Loss
CAMK_DAPK_DAPK_DAPK1_ST	Q13224	GRIN2B	P53355	DAPK1	S770	G763C	763	Missense	distal	-7	no	9.388	10.826	EPSD	ICGC	8.849	Up-regulation
CAMK_DAPK_DAPK_DAPK1_ST	Q13224	GRIN2B	P53355	DAPK1	S770	G763V	763	Missense	distal	-7	no	9.388	9.656	EPSD	ICGC;COSMIC	8.849	Up-regulation
CAMK_DAPK_DAPK_DAPK1_ST	Q13224	GRIN2B	P53355	DAPK1	S770	Q775H	775	Missense	distal	5	no	9.388	8.981	EPSD	ICGC;COSMIC	8.849	Down-regulation
CAMK_DAPK_DAPK_DAPK1_ST	Q13224	GRIN2B	P53355	DAPK1	S882	I877N	877	Missense	distal	-5	no	8.702	8.888	EPSD	ICGC;COSMIC	8.849	Gain
CAMK_DAPK_DAPK_DAPK1_ST	Q13224	GRIN2B	P53355	DAPK1	T894	A889T	889	Missense	distal	-5	no	9.847	9.955	EPSD	ICGC;COSMIC	8.849	Up-regulation
CAMK_DAPK_DAPK_DAPK1_ST	Q13224	GRIN2B	P53355	DAPK1	S1303	D1305N	1305	Missense	proximal	2	no	18.959	19.327	PhosphoSitePlus	ICGC;COSMIC	8.849	Up-regulation
CAMK_DAPK_DAPK_DAPK1_ST	Q13224	GRIN2B	P53355	DAPK1	S1303	R1300W	1300	Missense	distal	-3	no	18.959	16.250	PhosphoSitePlus	ICGC;COSMIC	8.849	Down-regulation
CAMK_DAPK_DAPK_DAPK1_ST	Q13224	GRIN2B	P53355	DAPK1	S1303	S1303P	1303	Missense	central	0	yes	18.959	0.000	PhosphoSitePlus	ICGC	8.849	Loss
CAMK_DAPK_DAPK_DAPK1_ST	Q13224	GRIN2B	P53355	DAPK1	S1323	A1316T	1316	Missense	distal	-7	no	10.042	9.568	EPSD	ICGC;COSMIC	8.849	Down-regulation
CAMK_DAPK_DAPK_DAPK1_ST	Q13224	GRIN2B	P53355	DAPK1	S1323	R1320S	1320	Missense	distal	-3	no	10.042	7.512	EPSD	ICGC	8.849	Loss
CAMK_DAPK_DAPK_DAPK1_ST	Q13224	GRIN2B	P53355	DAPK1	S1323	G1328S	1328	Missense	distal	5	no	10.042	9.438	EPSD	ICGC	8.849	Down-regulation
CAMK_DAPK_DAPK_DAPK1_ST	Q13224	GRIN2B	P53355	DAPK1	S1323	R1329Q	1329	Missense	distal	6	no	10.042	10.134	EPSD	ICGC;COSMIC	8.849	Up-regulation
CAMK_DAPK_DAPK_DAPK1_ST	Q13224	GRIN2B	P53355	DAPK1	S1469	H1472N	1472	Missense	distal	3	no	9.651	10.268	EPSD	ICGC	8.849	Up-regulation
CAMK_DAPK_DAPK_DAPK1_ST	Q13224	GRIN2B	P53355	DAPK1	S1469	V1473A	1473	Missense	distal	4	no	9.651	8.367	EPSD	ICGC	8.849	Loss
CAMK_PKD_PRKD1_ST	Q8WUI4	HDAC7	Q15139	PRKD1	S42	R47Q	47	Missense	distal	5	no	5.084	5.061	EPSD	ICGC;COSMIC	4.507	Down-regulation
CAMK_PKD_PRKD1_ST	Q8WUI4	HDAC7	Q15139	PRKD1	S42	R47K	47	Missense	distal	5	no	5.084	5.028	EPSD	ICGC	4.507	Down-regulation
CAMK_PKD_PRKD1_ST	Q8WUI4	HDAC7	Q15139	PRKD1	S42	P45S	45	Missense	distal	3	no	5.084	5.094	EPSD	ICGC;COSMIC	4.507	Up-regulation
CAMK_PKD_PRKD1_ST	Q8WUI4	HDAC7	Q15139	PRKD1	S155	R151H	151	Missense	distal	-4	no	5.885	5.880	EPSD;PhosphoSitePlus	ICGC;COSMIC;CCLE	4.507	Down-regulation
CAMK_PKD_PRKD1_ST	Q8WUI4	HDAC7	Q15139	PRKD1	S155	S155F	155	Missense	central	0	yes	5.885	0.000	EPSD;PhosphoSitePlus	ICGC;COSMIC	4.507	Loss
CAMK_PKD_PRKD1_ST	Q8WUI4	HDAC7	Q15139	PRKD1	S181	P183T	183	Missense	proximal	2	no	8.641	8.615	EPSD	ICGC	4.507	Down-regulation
CAMK_PKD_PRKD1_ST	Q8WUI4	HDAC7	Q15139	PRKD1	S181	K179R	179	Missense	proximal	-2	no	8.641	10.172	EPSD	ICGC;COSMIC	4.507	Up-regulation
CAMK_PKD_PRKD1_ST	Q8WUI4	HDAC7	Q15139	PRKD1	S181	A182V	182	Missense	proximal	1	no	8.641	8.640	EPSD	ICGC;COSMIC	4.507	Down-regulation
CAMK_PKD_PRKD1_ST	Q8WUI4	HDAC7	Q15139	PRKD1	S354	R357L	357	Missense	distal	3	no	4.798	4.783	EPSD	ICGC;COSMIC	4.507	Down-regulation
CAMK_PKD_PRKD1_ST	Q8WUI4	HDAC7	Q15139	PRKD1	S358	R357L	357	Missense	proximal	-1	no	9.781	9.668	EPSD;PhosphoSitePlus	ICGC;COSMIC	4.507	Down-regulation
CAMK_PKD_PRKD1_ST	Q8WUI4	HDAC7	Q15139	PRKD1	S464	R462Q	462	Missense	proximal	-2	no	5.640	3.672	EPSD	ICGC;COSMIC;CCLE	4.507	Loss
CAMK_PKD_PRKD1_ST	Q8WUI4	HDAC7	Q15139	PRKD1	S464	G458R	458	Missense	distal	-6	no	5.640	5.678	EPSD	ICGC	4.507	Up-regulation
CAMK_PKD_PRKD1_ST	Q8WUI4	HDAC7	Q15139	PRKD1	T465	R462Q	462	Missense	distal	-3	no	5.412	1.000	EPSD	ICGC;COSMIC;CCLE	4.507	Loss
CAMK_PKD_PRKD1_ST	Q8WUI4	HDAC7	Q15139	PRKD1	T465	G458R	458	Missense	distal	-7	no	5.412	6.075	EPSD	ICGC	4.507	Up-regulation
CAMK_PKD_PRKD1_ST	Q8WUI4	HDAC7	Q15139	PRKD1	S482	R483Q	483	Missense	proximal	1	no	6.658	6.659	EPSD	ICGC;COSMIC	4.507	Up-regulation
CAMK_PKD_PRKD1_ST	Q8WUI4	HDAC7	Q15139	PRKD1	S486	R483Q	483	Missense	distal	-3	no	10.857	6.444	PhosphoSitePlus;EPSD	ICGC;COSMIC	4.507	Down-regulation
CAMK_PKD_PRKD1_ST	Q8WUI4	HDAC7	Q15139	PRKD1	S903	D906E	906	Missense	distal	3	no	6.132	6.152	EPSD	ICGC;COSMIC	4.507	Up-regulation
CAMK_PKD_PRKD1_ST	P35670	ATP7B	Q15139	PRKD1	S23	S23C	23	Missense	central	0	yes	4.625	0.000	EPSD	ICGC;COSMIC	4.507	Loss
CAMK_PKD_PRKD1_ST	P35670	ATP7B	Q15139	PRKD1	S229	I222V	222	Missense	distal	-7	no	6.288	6.224	EPSD	ICGC	4.507	Down-regulation
CAMK_PKD_PRKD1_ST	P35670	ATP7B	Q15139	PRKD1	S342	R339K	339	Missense	distal	-3	no	7.178	4.507	EPSD	ICGC;COSMIC	4.507	Down-regulation
CAMK_PKD_PRKD1_ST	P35670	ATP7B	Q15139	PRKD1	S342	D337H	337	Missense	distal	-5	no	7.178	7.999	EPSD	ICGC;COSMIC	4.507	Up-regulation
CAMK_PKD_PRKD1_ST	P35222	CTNNB1	Q15139	PRKD1	T332	T332N	332	Missense	central	0	yes	6.119	0.000	EPSD	ICGC;COSMIC	4.507	Loss
CAMK_PKD_PRKD1_ST	Q8WYL5	SSH1	Q15139	PRKD1	T11	S17L	17	Missense	distal	6	no	7.101	7.127	EPSD	ICGC	4.507	Up-regulation
CAMK_PKD_PRKD1_ST	Q8WYL5	SSH1	Q15139	PRKD1	S17	A19V	19	Missense	proximal	2	no	4.625	4.494	EPSD	ICGC;COSMIC	4.507	Loss
CAMK_PKD_PRKD1_ST	Q8WYL5	SSH1	Q15139	PRKD1	S17	S17L	17	Missense	central	0	yes	4.625	0.000	EPSD	ICGC	4.507	Loss
CAMK_PKD_PRKD1_ST	Q8WYL5	SSH1	Q15139	PRKD1	S17	P12A	12	Missense	distal	-5	no	4.625	5.531	EPSD	ICGC;COSMIC	4.507	Up-regulation
CAMK_PKD_PRKD1_ST	Q8WYL5	SSH1	Q15139	PRKD1	S39	V45M	45	Missense	distal	6	no	4.902	4.890	EPSD	ICGC	4.507	Down-regulation
CAMK_PKD_PRKD1_ST	Q8WYL5	SSH1	Q15139	PRKD1	S402	M395T	395	Missense	distal	-7	no	8.076	8.057	EPSD;PhosphoSitePlus	ICGC;COSMIC	4.507	Down-regulation
CAMK_PKD_PRKD1_ST	Q8WYL5	SSH1	Q15139	PRKD1	S402	I405M	405	Missense	distal	3	no	8.076	8.086	EPSD;PhosphoSitePlus	ICGC;COSMIC	4.507	Up-regulation
CAMK_PKD_PRKD1_ST	Q8WYL5	SSH1	Q15139	PRKD1	S402	A408E	408	Missense	distal	6	no	8.076	8.095	EPSD;PhosphoSitePlus	ICGC	4.507	Up-regulation
CAMK_PKD_PRKD1_ST	Q8WYL5	SSH1	Q15139	PRKD1	S402	T403K	403	Missense	proximal	1	no	8.076	8.077	EPSD;PhosphoSitePlus	ICGC	4.507	Up-regulation
CAMK_PKD_PRKD1_ST	Q8WYL5	SSH1	Q15139	PRKD1	S402	A401V	401	Missense	proximal	-1	no	8.076	7.897	EPSD;PhosphoSitePlus	ICGC;COSMIC	4.507	Down-regulation
CAMK_PKD_PRKD1_ST	Q8WYL5	SSH1	Q15139	PRKD1	T430	K424E	424	Missense	distal	-6	no	4.515	4.518	EPSD	ICGC	4.507	Up-regulation
CAMK_PKD_PRKD1_ST	Q8WYL5	SSH1	Q15139	PRKD1	T430	R427L	427	Missense	distal	-3	no	4.515	-0.412	EPSD	ICGC;COSMIC	4.507	Loss
CAMK_PKD_PRKD1_ST	Q8WYL5	SSH1	Q15139	PRKD1	T462	R459C	459	Missense	distal	-3	no	6.368	2.271	EPSD	ICGC;COSMIC	4.507	Loss
CAMK_PKD_PRKD1_ST	Q8WYL5	SSH1	Q15139	PRKD1	T462	D463E	463	Missense	proximal	1	no	6.368	6.369	EPSD	ICGC;COSMIC	4.507	Up-regulation
CAMK_PKD_PRKD1_ST	Q8WYL5	SSH1	Q15139	PRKD1	T462	R459S	459	Missense	distal	-3	no	6.368	1.932	EPSD	ICGC	4.507	Loss
CAMK_PKD_PRKD1_ST	Q8WYL5	SSH1	Q15139	PRKD1	T462	T462K	462	Missense	central	0	yes	6.368	0.000	EPSD	ICGC	4.507	Loss
CAMK_PKD_PRKD1_ST	Q8WYL5	SSH1	Q15139	PRKD1	T462	K456N	456	Missense	distal	-6	no	6.368	6.359	EPSD	ICGC;COSMIC	4.507	Down-regulation
CAMK_PKD_PRKD1_ST	Q8WYL5	SSH1	Q15139	PRKD1	S515	D516H	516	Missense	proximal	1	no	9.595	9.596	EPSD	ICGC;COSMIC	4.507	Up-regulation
CAMK_PKD_PRKD1_ST	Q8WYL5	SSH1	Q15139	PRKD1	S739	S739I	739	Missense	central	0	yes	6.389	0.000	EPSD	ICGC;COSMIC	4.507	Loss
CAMK_PKD_PRKD1_ST	Q8WYL5	SSH1	Q15139	PRKD1	S739	L734I	734	Missense	distal	-5	no	6.389	4.732	EPSD	ICGC	4.507	Down-regulation
CAMK_PKD_PRKD1_ST	Q8WYL5	SSH1	Q15139	PRKD1	S889	E884Q	884	Missense	distal	-5	no	4.497	4.951	EPSD	ICGC;COSMIC	4.507	Gain
CAMK_PKD_PRKD1_ST	Q8WYL5	SSH1	Q15139	PRKD1	S936	S938R	938	Missense	proximal	2	no	5.457	5.469	EPSD	ICGC	4.507	Up-regulation
CAMK_PKD_PRKD1_ST	Q8WYL5	SSH1	Q15139	PRKD1	S936	H942N	942	Missense	distal	6	no	5.457	5.475	EPSD	ICGC	4.507	Up-regulation
CAMK_PKD_PRKD1_ST	Q8WYL5	SSH1	Q15139	PRKD1	S937	H942N	942	Missense	distal	5	no	9.193	9.148	EPSD;PhosphoSitePlus	ICGC	4.507	Down-regulation
CAMK_PKD_PRKD1_ST	Q8WYL5	SSH1	Q15139	PRKD1	S978	H977Y	977	Missense	proximal	-1	no	9.563	9.295	PhosphoSitePlus;EPSD	ICGC	4.507	Down-regulation
CAMK_PKD_PRKD1_ST	Q8WYL5	SSH1	Q15139	PRKD1	S984	T986P	986	Missense	proximal	2	no	5.357	5.383	EPSD	ICGC	4.507	Up-regulation
CAMK_PKD_PRKD1_ST	Q8WYL5	SSH1	Q15139	PRKD1	S984	D991E	991	Missense	distal	7	no	5.357	5.358	EPSD	ICGC;COSMIC	4.507	Up-regulation
CAMK_PKD_PRKD1_ST	Q8WYL5	SSH1	Q15139	PRKD1	S984	T989K	989	Missense	distal	5	no	5.357	5.377	EPSD	ICGC;COSMIC	4.507	Up-regulation
CAMK_PKD_PRKD1_ST	Q8WYL5	SSH1	Q15139	PRKD1	S984	H977Y	977	Missense	distal	-7	no	5.357	4.948	EPSD	ICGC	4.507	Down-regulation
CAMK_PKD_PRKD1_ST	Q92934	BAD	Q15139	PRKD1	S74	R72S	72	Missense	proximal	-2	no	4.622	2.777	EPSD	ICGC	4.507	Loss
CAMK_PKD_PRKD1_ST	Q92934	BAD	Q15139	PRKD1	S74	T80K	80	Missense	distal	6	no	4.622	4.611	EPSD	ICGC	4.507	Down-regulation
CAMK_PKD_PRKD1_ST	Q92934	BAD	Q15139	PRKD1	S74	S74G	74	Missense	central	0	yes	4.622	0.000	EPSD	ICGC;COSMIC	4.507	Loss
CAMK_PKD_PRKD1_ST	Q92934	BAD	Q15139	PRKD1	S75	R72S	72	Missense	distal	-3	no	8.207	3.771	PhosphoSitePlus;EPSD	ICGC	4.507	Loss
CAMK_PKD_PRKD1_ST	Q92934	BAD	Q15139	PRKD1	S75	T80K	80	Missense	distal	5	no	8.207	8.227	PhosphoSitePlus;EPSD	ICGC	4.507	Up-regulation
CAMK_PKD_PRKD1_ST	Q92934	BAD	Q15139	PRKD1	S75	S74G	74	Missense	proximal	-1	no	8.207	7.947	PhosphoSitePlus;EPSD	ICGC;COSMIC	4.507	Down-regulation
CAMK_PKD_PRKD1_ST	Q92934	BAD	Q15139	PRKD1	S97	S99L	99	Missense	proximal	2	no	6.387	6.309	EPSD	ICGC	4.507	Down-regulation
CAMK_PKD_PRKD1_ST	Q92934	BAD	Q15139	PRKD1	S97	R94W	94	Missense	distal	-3	no	6.387	1.014	EPSD	ICGC	4.507	Loss
CAMK_PKD_PRKD1_ST	Q92934	BAD	Q15139	PRKD1	S99	S99L	99	Missense	central	0	yes	7.408	0.000	EPSD;PhosphoSitePlus	ICGC	4.507	Loss
CAMK_PKD_PRKD1_ST	Q92934	BAD	Q15139	PRKD1	S99	R94W	94	Missense	distal	-5	no	7.408	6.571	EPSD;PhosphoSitePlus	ICGC	4.507	Down-regulation
CAMK_PKD_PRKD1_ST	Q92934	BAD	Q15139	PRKD1	S118	R112S	112	Missense	distal	-6	no	7.427	7.422	EPSD;PhosphoSitePlus	ICGC	4.507	Down-regulation
CAMK_PKD_PRKD1_ST	Q92934	BAD	Q15139	PRKD1	S145	R149L	149	Missense	distal	4	no	6.629	6.638	EPSD	ICGC;COSMIC	4.507	Up-regulation
CAMK_PKD_PRKD1_ST	Q92934	BAD	Q15139	PRKD1	S164	S167F	167	Missense	distal	3	no	8.811	8.786	EPSD	ICGC	4.507	Down-regulation
CAMK_PKD_PRKD1_ST	Q96QB1	DLC1	Q15139	PRKD1	S354	A350V	350	Missense	distal	-4	no	5.871	5.862	EPSD	ICGC;COSMIC	4.507	Down-regulation
CAMK_PKD_PRKD1_ST	Q96QB1	DLC1	Q15139	PRKD1	S354	L352M	352	Missense	proximal	-2	no	5.871	6.775	EPSD	ICGC;COSMIC	4.507	Up-regulation
CAMK_PKD_PRKD1_ST	Q96QB1	DLC1	Q15139	PRKD1	S354	S354Y	354	Missense	central	0	yes	5.871	0.000	EPSD	ICGC	4.507	Loss
CAMK_PKD_PRKD1_ST	Q96QB1	DLC1	Q15139	PRKD1	S377	S374R	374	Missense	distal	-3	no	3.161	7.597	EPSD	ICGC	4.507	Gain
CAMK_PKD_PRKD1_ST	Q96QB1	DLC1	Q15139	PRKD1	S378	S374R	374	Missense	distal	-4	no	6.214	6.217	EPSD	ICGC	4.507	Up-regulation
CAMK_PKD_PRKD1_ST	Q96QB1	DLC1	Q15139	PRKD1	S378	P383Q	383	Missense	distal	5	no	6.214	6.257	EPSD	ICGC	4.507	Up-regulation
CAMK_PKD_PRKD1_ST	Q96QB1	DLC1	Q15139	PRKD1	S544	R542S	542	Missense	proximal	-2	no	4.714	2.869	EPSD	ICGC;COSMIC	4.507	Loss
CAMK_PKD_PRKD1_ST	Q96QB1	DLC1	Q15139	PRKD1	S544	R546T	546	Missense	proximal	2	no	4.714	4.635	EPSD	ICGC	4.507	Down-regulation
CAMK_PKD_PRKD1_ST	Q96QB1	DLC1	Q15139	PRKD1	S544	R542W	542	Missense	proximal	-2	no	4.714	1.251	EPSD	ICGC;COSMIC	4.507	Loss
CAMK_PKD_PRKD1_ST	Q96QB1	DLC1	Q15139	PRKD1	S548	R542S	542	Missense	distal	-6	no	6.637	6.631	EPSD	ICGC;COSMIC	4.507	Down-regulation
CAMK_PKD_PRKD1_ST	Q96QB1	DLC1	Q15139	PRKD1	S548	R546T	546	Missense	proximal	-2	no	6.637	4.476	EPSD	ICGC	4.507	Loss
CAMK_PKD_PRKD1_ST	Q96QB1	DLC1	Q15139	PRKD1	S548	R542W	542	Missense	distal	-6	no	6.637	6.603	EPSD	ICGC;COSMIC	4.507	Down-regulation
CAMK_PKD_PRKD1_ST	Q96QB1	DLC1	Q15139	PRKD1	S598	S596R	596	Missense	proximal	-2	no	7.237	9.081	EPSD	ICGC	4.507	Up-regulation
CAMK_PKD_PRKD1_ST	Q96QB1	DLC1	Q15139	PRKD1	S599	S596R	596	Missense	distal	-3	no	2.781	7.217	EPSD	ICGC	4.507	Gain
CAMK_PKD_PRKD1_ST	Q96QB1	DLC1	Q15139	PRKD1	S673	S678N	678	Missense	distal	5	no	9.600	9.539	EPSD	ICGC;COSMIC	4.507	Down-regulation
CAMK_PKD_PRKD1_ST	Q96QB1	DLC1	Q15139	PRKD1	S673	S679L	679	Missense	distal	6	no	9.600	9.627	EPSD	ICGC;COSMIC	4.507	Up-regulation
CAMK_PKD_PRKD1_ST	Q96QB1	DLC1	Q15139	PRKD1	S764	S766N	766	Missense	proximal	2	no	7.333	7.248	EPSD	ICGC;COSMIC	4.507	Down-regulation
CAMK_PKD_PRKD1_ST	Q96QB1	DLC1	Q15139	PRKD1	S766	S766N	766	Missense	central	0	yes	7.348	0.000	EPSD	ICGC;COSMIC	4.507	Loss
CAMK_PKD_PRKD1_ST	Q96QB1	DLC1	Q15139	PRKD1	S856	S859Y	859	Missense	distal	3	no	8.730	8.701	EPSD	ICGC;COSMIC	4.507	Down-regulation
CAMK_PKD_PRKD1_ST	Q96QB1	DLC1	Q15139	PRKD1	S869	L876M	876	Missense	distal	7	no	5.323	5.324	EPSD	ICGC;COSMIC	4.507	Up-regulation
CAMK_PKD_PRKD1_ST	Q96QB1	DLC1	Q15139	PRKD1	S871	L876M	876	Missense	distal	5	no	4.762	4.796	EPSD	ICGC;COSMIC	4.507	Up-regulation
CAMK_PKD_PRKD1_ST	P16220	CREB1	Q15139	PRKD1	S133	D140A	140	Missense	distal	7	no	11.270	11.271	EPSD;PhosphoSitePlus	ICGC;COSMIC	4.507	Up-regulation
CAMK_PKD_PRKD1_ST	P16220	CREB1	Q15139	PRKD1	S143	D140A	140	Missense	distal	-3	no	2.204	4.985	EPSD	ICGC;COSMIC	4.507	Gain
CAMK_PKD_PRKD1_ST	O00429	DNM1L	Q15139	PRKD1	T78	D74N	74	Missense	distal	-4	no	4.914	4.917	EPSD	ICGC	4.507	Up-regulation
CAMK_PKD_PRKD1_ST	O00429	DNM1L	Q15139	PRKD1	T78	D74E	74	Missense	distal	-4	no	4.914	4.921	EPSD	ICGC;COSMIC	4.507	Up-regulation
CAMK_PKD_PRKD1_ST	O00429	DNM1L	Q15139	PRKD1	T79	D74N	74	Missense	distal	-5	no	5.881	6.601	EPSD	ICGC	4.507	Up-regulation
CAMK_PKD_PRKD1_ST	O00429	DNM1L	Q15139	PRKD1	T79	D74E	74	Missense	distal	-5	no	5.881	5.656	EPSD	ICGC;COSMIC	4.507	Down-regulation
CAMK_PKD_PRKD1_ST	O00429	DNM1L	Q15139	PRKD1	S544	A539S	539	Missense	distal	-5	no	4.546	4.221	EPSD	ICGC	4.507	Loss
CAMK_PKD_PRKD1_ST	O00429	DNM1L	Q15139	PRKD1	S544	A541S	541	Missense	distal	-3	no	4.546	3.355	EPSD	ICGC	4.507	Loss
CAMK_PKD_PRKD1_ST	O00429	DNM1L	Q15139	PRKD1	S544	S548F	548	Missense	distal	4	no	4.546	4.570	EPSD	ICGC;COSMIC	4.507	Up-regulation
CAMK_PKD_PRKD1_ST	O00429	DNM1L	Q15139	PRKD1	S544	S548Y	548	Missense	distal	4	no	4.546	4.572	EPSD	ICGC;COSMIC	4.507	Up-regulation
CAMK_PKD_PRKD1_ST	O60602	TLR5	Q15139	PRKD1	S805	Q804H	804	Missense	proximal	-1	no	7.063	7.074	PhosphoSitePlus	ICGC	4.507	Up-regulation
CAMK_PKD_PRKD1_ST	O60602	TLR5	Q15139	PRKD1	S805	S805F	805	Missense	central	0	yes	7.063	0.000	PhosphoSitePlus	ICGC	4.507	Loss
CAMK_PKD_PRKD1_ST	O60602	TLR5	Q15139	PRKD1	S805	M801I	801	Missense	distal	-4	no	7.063	7.058	PhosphoSitePlus	ICGC	4.507	Down-regulation
CAMK_PKD_PRKD1_ST	Q7KZI7	MARK2	Q15139	PRKD1	S29	S32F	32	Missense	distal	3	no	5.003	4.978	EPSD	ICGC;COSMIC	4.507	Down-regulation
CAMK_PKD_PRKD1_ST	Q7KZI7	MARK2	Q15139	PRKD1	T329	K324N	324	Missense	distal	-5	no	3.988	4.787	EPSD	ICGC;COSMIC	4.507	Gain
CAMK_PKD_PRKD1_ST	Q7KZI7	MARK2	Q15139	PRKD1	S400	R397H	397	Missense	distal	-3	no	7.781	3.794	PhosphoSitePlus	ICGC;COSMIC	4.507	Loss
CAMK_PKD_PRKD1_ST	Q7KZI7	MARK2	Q15139	PRKD1	S448	P454S	454	Missense	distal	6	no	8.021	8.001	EPSD	ICGC;COSMIC	4.507	Down-regulation
CAMK_PKD_PRKD1_ST	Q7KZI7	MARK2	Q15139	PRKD1	T466	L461F	461	Missense	distal	-5	no	7.332	4.180	EPSD	ICGC	4.507	Loss
CAMK_PKD_PRKD1_ST	Q7KZI7	MARK2	Q15139	PRKD1	S648	R653L	653	Missense	distal	5	no	6.682	6.605	EPSD	ICGC;COSMIC	4.507	Down-regulation
CAMK_PKD_PRKD1_ST	Q7KZI7	MARK2	Q15139	PRKD1	S648	R653W	653	Missense	distal	5	no	6.682	6.563	EPSD	ICGC;COSMIC	4.507	Down-regulation
CAMK_PKD_PRKD1_ST	Q7KZI7	MARK2	Q15139	PRKD1	S759	L755R	755	Missense	distal	-4	no	4.501	4.511	EPSD	ICGC;COSMIC	4.507	Gain
CAMK_PKD_PRKD1_ST	Q15276	RABEP1	Q15139	PRKD1	S162	G164D	164	Missense	proximal	2	no	11.521	11.547	EPSD	ICGC;COSMIC	4.507	Up-regulation
CAMK_PKD_PRKD1_ST	Q15276	RABEP1	Q15139	PRKD1	S229	C230F	230	Missense	proximal	1	no	6.146	6.145	EPSD	ICGC	4.507	Down-regulation
CAMK_PKD_PRKD1_ST	Q15276	RABEP1	Q15139	PRKD1	S246	L241S	241	Missense	distal	-5	no	6.356	4.093	EPSD	ICGC;COSMIC	4.507	Loss
CAMK_PKD_PRKD1_ST	Q15276	RABEP1	Q15139	PRKD1	S357	N363S	363	Missense	distal	6	no	4.699	4.671	EPSD	ICGC;COSMIC	4.507	Down-regulation
CAMK_PKD_PRKD1_ST	Q15276	RABEP1	Q15139	PRKD1	S357	Q354H	354	Missense	distal	-3	no	4.699	5.125	EPSD	ICGC;COSMIC	4.507	Up-regulation
CAMK_PKD_PRKD1_ST	Q15276	RABEP1	Q15139	PRKD1	S357	A351S	351	Missense	distal	-6	no	4.699	4.695	EPSD	ICGC;COSMIC	4.507	Down-regulation
CAMK_PKD_PRKD1_ST	Q15276	RABEP1	Q15139	PRKD1	S374	G373V	373	Missense	proximal	-1	no	4.566	4.681	EPSD	ICGC	4.507	Up-regulation
CAMK_PKD_PRKD1_ST	Q15276	RABEP1	Q15139	PRKD1	S447	S449Y	449	Missense	proximal	2	no	5.023	4.853	EPSD	ICGC;COSMIC	4.507	Down-regulation
CAMK_PKD_PRKD1_ST	Q15276	RABEP1	Q15139	PRKD1	S447	A445G	445	Missense	proximal	-2	no	5.023	3.282	EPSD	ICGC;COSMIC	4.507	Loss
CAMK_PKD_PRKD1_ST	Q15276	RABEP1	Q15139	PRKD1	S464	S459L	459	Missense	distal	-5	no	2.582	4.845	EPSD	ICGC;COSMIC	4.507	Gain
CAMK_PKD_PRKD1_ST	Q15276	RABEP1	Q15139	PRKD1	S511	G506C	506	Missense	distal	-5	no	4.371	5.077	EPSD	ICGC;COSMIC	4.507	Gain
CAMK_PKD_PRKD1_ST	O75628	REM1	Q15139	PRKD1	S18	R16Q	16	Missense	proximal	-2	no	10.863	8.895	PhosphoSitePlus	ICGC;COSMIC	4.507	Down-regulation
CAMK_PKD_PRKD1_ST	O75628	REM1	Q15139	PRKD1	S18	P20L	20	Missense	proximal	2	no	10.863	10.827	PhosphoSitePlus	ICGC;COSMIC;CCLE	4.507	Down-regulation
CAMK_PKD_PRKD1_ST	O75628	REM1	Q15139	PRKD1	S18	R15W	15	Missense	distal	-3	no	10.863	5.490	PhosphoSitePlus	ICGC;COSMIC;CCLE	4.507	Down-regulation
CAMK_PKD_PRKD1_ST	O75628	REM1	Q15139	PRKD1	T19	R16Q	16	Missense	distal	-3	no	6.291	1.878	EPSD	ICGC;COSMIC	4.507	Loss
CAMK_PKD_PRKD1_ST	O75628	REM1	Q15139	PRKD1	T19	R15W	15	Missense	distal	-4	no	6.291	6.278	EPSD	ICGC;COSMIC;CCLE	4.507	Down-regulation
CAMK_PKD_PRKD1_ST	O75628	REM1	Q15139	PRKD1	T19	R26W	26	Missense	distal	7	no	6.291	6.290	EPSD	ICGC;COSMIC;CCLE	4.507	Down-regulation
CAMK_PKD_PRKD1_ST	O75628	REM1	Q15139	PRKD1	S51	S51Y	51	Missense	central	0	yes	5.252	0.000	EPSD	ICGC;COSMIC	4.507	Loss
CAMK_PKD_PRKD1_ST	O75628	REM1	Q15139	PRKD1	S51	P54H	54	Missense	distal	3	no	5.252	5.262	EPSD	ICGC;COSMIC	4.507	Up-regulation
CAMK_PKD_PRKD1_ST	O75628	REM1	Q15139	PRKD1	S250	R244H	244	Missense	distal	-6	no	10.549	10.536	EPSD	ICGC;COSMIC;CCLE	4.507	Down-regulation
CAMK_PKD_PRKD1_ST	O75628	REM1	Q15139	PRKD1	S250	R247C	247	Missense	distal	-3	no	10.549	6.452	EPSD	ICGC;COSMIC	4.507	Down-regulation
CAMK_PKD_PRKD1_ST	O75628	REM1	Q15139	PRKD1	S250	R244C	244	Missense	distal	-6	no	10.549	10.530	EPSD	ICGC	4.507	Down-regulation
CAMK_PKD_PRKD1_ST	O75628	REM1	Q15139	PRKD1	S289	A284T	284	Missense	distal	-5	no	5.236	4.569	EPSD	ICGC;COSMIC	4.507	Down-regulation
CAMK_PKD_PRKD1_ST	O75628	REM1	Q15139	PRKD1	S291	A284T	284	Missense	distal	-7	no	5.293	5.033	EPSD	ICGC;COSMIC	4.507	Down-regulation
CAMK_PKD_PRKD1_ST	Q9NRA0	SPHK2	Q15139	PRKD1	S421	P426S	426	Missense	distal	5	no	8.102	8.148	PhosphoSitePlus;EPSD	ICGC	4.507	Up-regulation
CAMK_PKD_PRKD1_ST	Q99683	MAP3K5	Q15139	PRKD1	S613	E618D	618	Missense	distal	5	no	6.022	5.961	EPSD	ICGC;COSMIC	4.507	Down-regulation
CAMK_PKD_PRKD1_ST	Q99683	MAP3K5	Q15139	PRKD1	S719	P721H	721	Missense	proximal	2	no	5.470	5.485	EPSD	ICGC	4.507	Up-regulation
CAMK_PKD_PRKD1_ST	Q99683	MAP3K5	Q15139	PRKD1	S719	S716R	716	Missense	distal	-3	no	5.470	9.906	EPSD	ICGC	4.507	Up-regulation
CAMK_PKD_PRKD1_ST	Q99683	MAP3K5	Q15139	PRKD1	S719	S719Y	719	Missense	central	0	yes	5.470	0.000	EPSD	ICGC;COSMIC	4.507	Loss
CAMK_PKD_PRKD1_ST	O96013	PAK4	Q15139	PRKD1	S99	R96C	96	Missense	distal	-3	no	8.722	4.625	PhosphoSitePlus	ICGC;COSMIC	4.507	Down-regulation
CAMK_PKD_PRKD1_ST	O96013	PAK4	Q15139	PRKD1	S99	R101W	101	Missense	proximal	2	no	8.722	8.574	PhosphoSitePlus	ICGC;COSMIC	4.507	Down-regulation
CAMK_PKD_PRKD1_ST	O96013	PAK4	Q15139	PRKD1	S104	R110L	110	Missense	distal	6	no	9.929	9.944	EPSD	ICGC	4.507	Up-regulation
CAMK_PKD_PRKD1_ST	O96013	PAK4	Q15139	PRKD1	S104	R101W	101	Missense	distal	-3	no	9.929	4.556	EPSD	ICGC;COSMIC	4.507	Down-regulation
CAMK_PKD_PRKD1_ST	O96013	PAK4	Q15139	PRKD1	S181	D176G	176	Missense	distal	-5	no	6.506	6.313	EPSD	ICGC;COSMIC	4.507	Down-regulation
CAMK_PKD_PRKD1_ST	O96013	PAK4	Q15139	PRKD1	T213	P209Q	209	Missense	distal	-4	no	4.657	4.659	EPSD	ICGC;COSMIC	4.507	Up-regulation
CAMK_PKD_PRKD1_ST	O96013	PAK4	Q15139	PRKD1	T213	T213M	213	Missense	central	0	yes	4.657	0.000	EPSD	ICGC	4.507	Loss
CAMK_PKD_PRKD1_ST	O96013	PAK4	Q15139	PRKD1	T251	P250L	250	Missense	proximal	-1	no	5.212	5.276	EPSD	ICGC	4.507	Up-regulation
CAMK_PKD_PRKD1_ST	O96013	PAK4	Q15139	PRKD1	S474	V476D	476	Missense	proximal	2	no	11.240	11.200	EPSD	ICGC;COSMIC	4.507	Down-regulation
CAMK_PKD_PRKD1_ST	P27986	PIK3R1	Q15139	PRKD1	S154	R151L	151	Missense	distal	-3	no	9.099	4.171	PhosphoSitePlus	ICGC;COSMIC	4.507	Loss
CAMK_PKD_PRKD1_ST	P27986	PIK3R1	Q15139	PRKD1	S154	R151C	151	Missense	distal	-3	no	9.099	5.002	PhosphoSitePlus	ICGC;COSMIC	4.507	Down-regulation
CAMK_PKD_PRKD1_ST	P27986	PIK3R1	Q15139	PRKD1	S156	R151L	151	Missense	distal	-5	no	3.861	5.741	EPSD	ICGC;COSMIC	4.507	Gain
CAMK_PKD_PRKD1_ST	P27986	PIK3R1	Q15139	PRKD1	S269	F275L	275	Missense	distal	6	no	4.783	4.762	EPSD	ICGC;COSMIC	4.507	Down-regulation
CAMK_PKD_PRKD1_ST	P27986	PIK3R1	Q15139	PRKD1	S280	F275L	275	Missense	distal	-5	no	3.285	6.437	EPSD	ICGC;COSMIC	4.507	Gain
CAMK_PKD_PRKD1_ST	P31749	AKT1	Q15139	PRKD1	T72	T65K	65	Missense	distal	-7	no	4.787	4.976	EPSD	ICGC	4.507	Up-regulation
CAMK_PKD_PRKD1_ST	P31749	AKT1	Q15139	PRKD1	S246	D248H	248	Missense	proximal	2	no	6.314	6.418	EPSD	ICGC;COSMIC	4.507	Up-regulation
CAMK_PKD_PRKD1_ST	P31749	AKT1	Q15139	PRKD1	S246	A250D	250	Missense	distal	4	no	6.314	6.341	EPSD	ICGC	4.507	Up-regulation
CAMK_PKD_PRKD1_ST	P31749	AKT1	Q15139	PRKD1	S246	E242K	242	Missense	distal	-4	no	6.314	6.316	EPSD	ICGC	4.507	Up-regulation
CAMK_PKD_PRKD1_ST	P31749	AKT1	Q15139	PRKD1	S246	V244A	244	Missense	proximal	-2	no	6.314	8.470	EPSD	ICGC	4.507	Up-regulation
CAMK_PKD_PRKD1_ST	P31749	AKT1	Q15139	PRKD1	S246	R249W	249	Missense	distal	3	no	6.314	6.285	EPSD	ICGC;COSMIC	4.507	Down-regulation
CAMK_PKD_PRKD1_ST	P31749	AKT1	Q15139	PRKD1	S246	R251S	251	Missense	distal	5	no	6.314	6.294	EPSD	ICGC;COSMIC	4.507	Down-regulation
CAMK_PKD_PRKD1_ST	P31749	AKT1	Q15139	PRKD1	S422	K420T	420	Missense	proximal	-2	no	5.041	4.411	EPSD	ICGC	4.507	Loss
CAMK_PKD_PRKD1_ST	Q96A00	PPP1R14A	Q15139	PRKD1	S12	R9C	9	Missense	distal	-3	no	5.619	1.522	EPSD	ICGC	4.507	Loss
CAMK_PKD_PRKD1_ST	Q96A00	PPP1R14A	Q15139	PRKD1	S16	R21C	21	Missense	distal	5	no	6.215	6.149	EPSD	ICGC;COSMIC	4.507	Down-regulation
CAMK_PKD_PRKD1_ST	Q96A00	PPP1R14A	Q15139	PRKD1	S16	R9C	9	Missense	distal	-7	no	6.215	5.762	EPSD	ICGC	4.507	Down-regulation
CAMK_PKD_PRKD1_ST	Q96A00	PPP1R14A	Q15139	PRKD1	T38	Q31K	31	Missense	distal	-7	no	6.887	6.902	PhosphoSitePlus	ICGC	4.507	Up-regulation
CAMK_PKD_PRKD1_ST	Q96A00	PPP1R14A	Q15139	PRKD1	T38	H34Y	34	Missense	distal	-4	no	6.887	6.878	PhosphoSitePlus	ICGC;COSMIC	4.507	Down-regulation
CAMK_PKD_PRKD1_ST	Q96A00	PPP1R14A	Q15139	PRKD1	T38	H34Q	34	Missense	distal	-4	no	6.887	6.888	PhosphoSitePlus	ICGC	4.507	Up-regulation
CAMK_PKD_PRKD1_ST	Q96A00	PPP1R14A	Q15139	PRKD1	T38	A35T	35	Missense	distal	-3	no	6.887	6.621	PhosphoSitePlus	ICGC;COSMIC	4.507	Down-regulation
CAMK_PKD_PRKD1_ST	Q14896	MYBPC3	Q15139	PRKD1	S275	R281W	281	Missense	distal	6	no	9.937	9.969	EPSD	ICGC;COSMIC	4.507	Up-regulation
CAMK_PKD_PRKD1_ST	Q14896	MYBPC3	Q15139	PRKD1	S275	G280V	280	Missense	distal	5	no	9.937	10.001	EPSD	ICGC;COSMIC	4.507	Up-regulation
CAMK_PKD_PRKD1_ST	Q14896	MYBPC3	Q15139	PRKD1	S284	R281W	281	Missense	distal	-3	no	6.808	1.435	EPSD	ICGC;COSMIC	4.507	Loss
CAMK_PKD_PRKD1_ST	Q14896	MYBPC3	Q15139	PRKD1	S284	R282Q	282	Missense	proximal	-2	no	6.808	4.840	EPSD	ICGC;COSMIC	4.507	Down-regulation
CAMK_PKD_PRKD1_ST	Q14896	MYBPC3	Q15139	PRKD1	S284	E288A	288	Missense	distal	4	no	6.808	6.793	EPSD	ICGC;COSMIC	4.507	Down-regulation
CAMK_PKD_PRKD1_ST	Q14896	MYBPC3	Q15139	PRKD1	S284	G280V	280	Missense	distal	-4	no	6.808	6.809	EPSD	ICGC;COSMIC	4.507	Up-regulation
CAMK_PKD_PRKD1_ST	Q14896	MYBPC3	Q15139	PRKD1	S304	R302K	302	Missense	proximal	-2	no	10.158	8.627	PhosphoSitePlus	ICGC	4.507	Down-regulation
CAMK_PKD_PRKD1_ST	Q14896	MYBPC3	Q15139	PRKD1	S424	R419L	419	Missense	distal	-5	no	3.092	4.972	EPSD	ICGC;COSMIC	4.507	Gain
CAMK_PKD_PRKD1_ST	Q14896	MYBPC3	Q15139	PRKD1	S830	D824V	824	Missense	distal	-6	no	5.021	5.026	EPSD	ICGC;COSMIC	4.507	Up-regulation
CAMK_PKD_PRKD1_ST	O60331	PIP5K1C	Q15139	PRKD1	S11	P6L	6	Missense	distal	-5	no	3.622	6.467	EPSD	ICGC	4.507	Gain
CAMK_PKD_PRKD1_ST	O60331	PIP5K1C	Q15139	PRKD1	S228	V226M	226	Missense	proximal	-2	no	3.524	5.029	EPSD	ICGC;COSMIC	4.507	Gain
CAMK_PKD_PRKD1_ST	O60331	PIP5K1C	Q15139	PRKD1	S448	S449Y	449	Missense	proximal	1	no	7.969	7.968	PhosphoSitePlus	ICGC	4.507	Down-regulation
CAMK_PKD_PRKD1_ST	O60331	PIP5K1C	Q15139	PRKD1	S448	T442K	442	Missense	distal	-6	no	7.969	7.978	PhosphoSitePlus	ICGC;COSMIC	4.507	Up-regulation
CAMK_PKD_PRKD1_ST	O60331	PIP5K1C	Q15139	PRKD1	S455	S449Y	449	Missense	distal	-6	no	4.692	4.660	EPSD	ICGC	4.507	Down-regulation
CAMK_PKD_PRKD1_ST	O60331	PIP5K1C	Q15139	PRKD1	S455	G458W	458	Missense	distal	3	no	4.692	4.695	EPSD	ICGC;COSMIC	4.507	Up-regulation
CAMK_PKD_PRKD1_ST	O60331	PIP5K1C	Q15139	PRKD1	S455	S455P	455	Missense	central	0	yes	4.692	0.000	EPSD	ICGC;COSMIC	4.507	Loss
CAMK_PKD_PRKD1_ST	O60331	PIP5K1C	Q15139	PRKD1	S496	D502E	502	Missense	distal	6	no	4.536	4.512	EPSD	ICGC	4.507	Down-regulation
CAMK_PKD_PRKD1_ST	O60331	PIP5K1C	Q15139	PRKD1	S496	L500M	500	Missense	distal	4	no	4.536	4.532	EPSD	ICGC	4.507	Down-regulation
CAMK_PKD_PRKD1_ST	O60331	PIP5K1C	Q15139	PRKD1	S496	R495S	495	Missense	proximal	-1	no	4.536	4.455	EPSD	ICGC;COSMIC	4.507	Loss
CAMK_PKD_PRKD1_ST	O60331	PIP5K1C	Q15139	PRKD1	S541	P536H	536	Missense	distal	-5	no	7.574	8.417	EPSD	ICGC	4.507	Up-regulation
CAMK_PKD_PRKD1_ST	O60331	PIP5K1C	Q15139	PRKD1	S541	S544L	544	Missense	distal	3	no	7.574	7.566	EPSD	ICGC;COSMIC	4.507	Down-regulation
CAMK_PKD_PRKD1_ST	O60331	PIP5K1C	Q15139	PRKD1	T553	T553A	553	Missense	central	0	yes	8.040	0.000	EPSD	ICGC	4.507	Loss
CAMK_PKD_PRKD1_ST	O60331	PIP5K1C	Q15139	PRKD1	S555	P562L	562	Missense	distal	7	no	7.198	7.197	EPSD	ICGC	4.507	Down-regulation
CAMK_PKD_PRKD1_ST	O60331	PIP5K1C	Q15139	PRKD1	S555	T553A	553	Missense	proximal	-2	no	7.198	7.805	EPSD	ICGC	4.507	Up-regulation
CAMK_PKD_PRKD1_ST	Q15139	PRKD1	Q15139	PRKD1	S205	R203S	203	Missense	proximal	-2	no	10.262	8.417	EPSD	ICGC;COSMIC	4.507	Down-regulation
CAMK_PKD_PRKD1_ST	Q15139	PRKD1	Q15139	PRKD1	S205	G198S	198	Missense	distal	-7	no	10.262	10.644	EPSD	ICGC;COSMIC	4.507	Up-regulation
CAMK_PKD_PRKD1_ST	Q15139	PRKD1	Q15139	PRKD1	S205	V207F	207	Missense	proximal	2	no	10.262	10.207	EPSD	ICGC;COSMIC	4.507	Down-regulation
CAMK_PKD_PRKD1_ST	Q15139	PRKD1	Q15139	PRKD1	S205	G198C	198	Missense	distal	-7	no	10.262	10.471	EPSD	ICGC;COSMIC	4.507	Up-regulation
CAMK_PKD_PRKD1_ST	Q15139	PRKD1	Q15139	PRKD1	S219	R216H	216	Missense	distal	-3	no	6.546	2.559	EPSD	ICGC	4.507	Loss
CAMK_PKD_PRKD1_ST	Q15139	PRKD1	Q15139	PRKD1	S223	R216H	216	Missense	distal	-7	no	4.978	4.616	EPSD	ICGC	4.507	Down-regulation
CAMK_PKD_PRKD1_ST	Q15139	PRKD1	Q15139	PRKD1	S237	E244V	244	Missense	distal	7	no	7.026	7.025	EPSD	ICGC;COSMIC	4.507	Down-regulation
CAMK_PKD_PRKD1_ST	Q15139	PRKD1	Q15139	PRKD1	S249	G254A	254	Missense	distal	5	no	5.773	5.919	EPSD	ICGC;COSMIC	4.507	Up-regulation
CAMK_PKD_PRKD1_ST	Q15139	PRKD1	Q15139	PRKD1	S249	E244V	244	Missense	distal	-5	no	5.773	7.288	EPSD	ICGC;COSMIC	4.507	Up-regulation
CAMK_PKD_PRKD1_ST	Q15139	PRKD1	Q15139	PRKD1	S249	S247L	247	Missense	proximal	-2	no	5.773	4.509	EPSD	ICGC;COSMIC	4.507	Down-regulation
CAMK_PKD_PRKD1_ST	Q15139	PRKD1	Q15139	PRKD1	S420	R418K	418	Missense	proximal	-2	no	6.150	4.619	EPSD	ICGC;COSMIC	4.507	Down-regulation
CAMK_PKD_PRKD1_ST	Q15139	PRKD1	Q15139	PRKD1	S420	M424T	424	Missense	distal	4	no	6.150	6.162	EPSD	ICGC;COSMIC	4.507	Up-regulation
CAMK_PKD_PRKD1_ST	Q15139	PRKD1	Q15139	PRKD1	S421	R418K	418	Missense	distal	-3	no	6.747	4.075	EPSD	ICGC;COSMIC	4.507	Loss
CAMK_PKD_PRKD1_ST	Q15139	PRKD1	Q15139	PRKD1	S421	M424T	424	Missense	distal	3	no	6.747	6.736	EPSD	ICGC;COSMIC	4.507	Down-regulation
CAMK_PKD_PRKD1_ST	Q15139	PRKD1	Q15139	PRKD1	S742	R740W	740	Missense	proximal	-2	no	5.218	1.755	EPSD;PhosphoSitePlus	ICGC;COSMIC;GDSC;CCLE	4.507	Loss
CAMK_PKD_PRKD1_ST	Q15139	PRKD1	Q15139	PRKD1	S742	R740L	740	Missense	proximal	-2	no	5.218	2.110	EPSD;PhosphoSitePlus	ICGC;COSMIC	4.507	Loss
CAMK_PKD_PRKD1_ST	Q13936	CACNA1C	Q15139	PRKD1	S465	T468I	468	Missense	distal	3	no	6.235	6.236	EPSD	ICGC;COSMIC	4.507	Up-regulation
CAMK_PKD_PRKD1_ST	Q13936	CACNA1C	Q15139	PRKD1	S465	S465I	465	Missense	central	0	yes	6.235	0.000	EPSD	ICGC	4.507	Loss
CAMK_PKD_PRKD1_ST	Q13936	CACNA1C	Q15139	PRKD1	S465	E459K	459	Missense	distal	-6	no	6.235	6.232	EPSD	ICGC;COSMIC	4.507	Down-regulation
CAMK_PKD_PRKD1_ST	Q13936	CACNA1C	Q15139	PRKD1	S863	R858C	858	Missense	distal	-5	no	7.174	6.745	EPSD	ICGC;COSMIC	4.507	Down-regulation
CAMK_PKD_PRKD1_ST	Q13936	CACNA1C	Q15139	PRKD1	S863	G856S	856	Missense	distal	-7	no	7.174	7.556	EPSD	ICGC;COSMIC	4.507	Up-regulation
CAMK_PKD_PRKD1_ST	Q13936	CACNA1C	Q15139	PRKD1	S863	L865I	865	Missense	proximal	2	no	7.174	7.166	EPSD	ICGC;COSMIC	4.507	Down-regulation
CAMK_PKD_PRKD1_ST	Q13936	CACNA1C	Q15139	PRKD1	S863	E869K	869	Missense	distal	6	no	7.174	7.175	EPSD	ICGC;COSMIC	4.507	Up-regulation
CAMK_PKD_PRKD1_ST	Q13936	CACNA1C	Q15139	PRKD1	S863	L862R	862	Missense	proximal	-1	no	7.174	7.287	EPSD	ICGC;COSMIC	4.507	Up-regulation
CAMK_PKD_PRKD1_ST	Q13936	CACNA1C	Q15139	PRKD1	S863	H866N	866	Missense	distal	3	no	7.174	7.162	EPSD	ICGC	4.507	Down-regulation
CAMK_PKD_PRKD1_ST	Q13936	CACNA1C	Q15139	PRKD1	S1692	R1694Q	1694	Missense	proximal	2	no	5.756	5.739	EPSD	ICGC;COSMIC	4.507	Down-regulation
CAMK_PKD_PRKD1_ST	Q13936	CACNA1C	Q15139	PRKD1	S1692	R1694G	1694	Missense	proximal	2	no	5.756	5.588	EPSD	ICGC;COSMIC	4.507	Down-regulation
CAMK_PKD_PRKD1_ST	Q13936	CACNA1C	Q15139	PRKD1	S1692	P1691H	1691	Missense	proximal	-1	no	5.756	5.820	EPSD	ICGC;COSMIC;CCLE	4.507	Up-regulation
CAMK_PKD_PRKD1_ST	Q13936	CACNA1C	Q15139	PRKD1	S1736	V1735I	1735	Missense	proximal	-1	no	5.230	5.236	EPSD	ICGC;COSMIC	4.507	Up-regulation
CAMK_PKD_PRKD1_ST	Q14247	CTTN	Q15139	PRKD1	S113	V115L	115	Missense	proximal	2	no	8.345	8.358	EPSD	ICGC	4.507	Up-regulation
CAMK_PKD_PRKD1_ST	Q14247	CTTN	Q15139	PRKD1	S150	K144N	144	Missense	distal	-6	no	5.979	5.970	EPSD	ICGC	4.507	Down-regulation
CAMK_PKD_PRKD1_ST	Q14247	CTTN	Q15139	PRKD1	S187	G180V	180	Missense	distal	-7	no	5.401	5.363	EPSD	ICGC;COSMIC	4.507	Down-regulation
CAMK_PKD_PRKD1_ST	Q14247	CTTN	Q15139	PRKD1	S187	S187P	187	Missense	central	0	yes	5.401	0.000	EPSD	ICGC	4.507	Loss
CAMK_PKD_PRKD1_ST	Q14247	CTTN	Q15139	PRKD1	S192	G196D	196	Missense	distal	4	no	4.857	4.851	EPSD	ICGC;COSMIC	4.507	Down-regulation
CAMK_PKD_PRKD1_ST	Q14247	CTTN	Q15139	PRKD1	S192	S187P	187	Missense	distal	-5	no	4.857	4.275	EPSD	ICGC	4.507	Loss
CAMK_PKD_PRKD1_ST	Q14247	CTTN	Q15139	PRKD1	S192	G197D	197	Missense	distal	5	no	4.857	4.883	EPSD	ICGC;COSMIC	4.507	Up-regulation
CAMK_PKD_PRKD1_ST	Q14247	CTTN	Q15139	PRKD1	S224	G231R	231	Missense	distal	7	no	5.481	5.482	EPSD	ICGC	4.507	Up-regulation
CAMK_PKD_PRKD1_ST	Q14247	CTTN	Q15139	PRKD1	S282	D288N	288	Missense	distal	6	no	7.855	7.841	EPSD	ICGC;COSMIC	4.507	Down-regulation
CAMK_PKD_PRKD1_ST	Q14247	CTTN	Q15139	PRKD1	S282	A283V	283	Missense	proximal	1	no	7.855	7.854	EPSD	ICGC;COSMIC	4.507	Down-regulation
CAMK_PKD_PRKD1_ST	Q14247	CTTN	Q15139	PRKD1	S282	D288H	288	Missense	distal	6	no	7.855	7.823	EPSD	ICGC;COSMIC	4.507	Down-regulation
CAMK_PKD_PRKD1_ST	Q14247	CTTN	Q15139	PRKD1	S282	V275F	275	Missense	distal	-7	no	7.855	7.895	EPSD	ICGC;COSMIC	4.507	Up-regulation
CAMK_PKD_PRKD1_ST	Q14247	CTTN	Q15139	PRKD1	S282	S282F	282	Missense	central	0	yes	7.855	0.000	EPSD	ICGC	4.507	Loss
CAMK_PKD_PRKD1_ST	Q14247	CTTN	Q15139	PRKD1	S282	E278D	278	Missense	distal	-4	no	7.855	7.848	EPSD	ICGC	4.507	Down-regulation
CAMK_PKD_PRKD1_ST	Q14247	CTTN	Q15139	PRKD1	S348	T347A	347	Missense	proximal	-1	no	4.368	4.516	PhosphoSitePlus;EPSD	ICGC;COSMIC	4.507	Gain
CAMK_PKD_PRKD1_ST	Q14247	CTTN	Q15139	PRKD1	T399	T401M	401	Missense	proximal	2	no	4.593	4.621	EPSD	ICGC;COSMIC	4.507	Up-regulation
CAMK_PKD_PRKD1_ST	Q14247	CTTN	Q15139	PRKD1	T399	T401A	401	Missense	proximal	2	no	4.593	4.701	EPSD	ICGC	4.507	Up-regulation
CAMK_PKD_PRKD1_ST	Q14247	CTTN	Q15139	PRKD1	T399	S405L	405	Missense	distal	6	no	4.593	4.620	EPSD	ICGC;COSMIC;GDSC	4.507	Up-regulation
CAMK_PKD_PRKD1_ST	Q14247	CTTN	Q15139	PRKD1	S417	E412K	412	Missense	distal	-5	no	4.786	4.931	EPSD	ICGC;COSMIC	4.507	Up-regulation
CAMK_PKD_PRKD1_ST	Q14247	CTTN	Q15139	PRKD1	S417	L415P	415	Missense	proximal	-2	no	4.786	5.728	EPSD	ICGC	4.507	Up-regulation
CAMK_PKD_PRKD1_ST	P05412	JUN	Q15139	PRKD1	S73	A72E	72	Missense	proximal	-1	no	6.605	6.464	EPSD	ICGC;COSMIC	4.507	Down-regulation
CAMK_PKD_PRKD1_ST	P05412	JUN	Q15139	PRKD1	S73	K70T	70	Missense	distal	-3	no	6.605	5.765	EPSD	ICGC;COSMIC	4.507	Down-regulation
CAMK_PKD_PRKD1_ST	Q9UBF8	PI4KB	Q15139	PRKD1	S275	S268P	268	Missense	distal	-7	no	4.526	4.413	EPSD	ICGC;COSMIC	4.507	Loss
CAMK_PKD_PRKD1_ST	Q9UBF8	PI4KB	Q15139	PRKD1	S445	T438K	438	Missense	distal	-7	no	7.009	7.197	EPSD	ICGC	4.507	Up-regulation
CAMK_PKD_PRKD1_ST	Q9UBF8	PI4KB	Q15139	PRKD1	S511	A515E	515	Missense	distal	4	no	9.801	9.816	EPSD	ICGC	4.507	Up-regulation
CAMK_PKD_PRKD1_ST	Q9Y3E5	PTRH2	Q15139	PRKD1	S87	A84V	84	Missense	distal	-3	no	5.243	2.294	EPSD;PhosphoSitePlus	ICGC;COSMIC	4.507	Loss
CAMK_PKD_PRKD1_ST	Q9Y3E5	PTRH2	Q15139	PRKD1	S87	A90V	90	Missense	distal	3	no	5.243	5.226	EPSD;PhosphoSitePlus	ICGC;COSMIC;GDSC;CCLE	4.507	Down-regulation
CAMK_PKD_PRKD1_ST	Q9BST9	RTKN	Q15139	PRKD1	T11	S8R	8	Missense	distal	-3	no	3.249	7.685	EPSD	ICGC;COSMIC	4.507	Gain
CAMK_PKD_PRKD1_ST	Q9BST9	RTKN	Q15139	PRKD1	S63	A68T	68	Missense	distal	5	no	6.259	6.181	EPSD	ICGC;COSMIC	4.507	Down-regulation
CAMK_PKD_PRKD1_ST	Q9BST9	RTKN	Q15139	PRKD1	S63	A60T	60	Missense	distal	-3	no	6.259	5.993	EPSD	ICGC;COSMIC	4.507	Down-regulation
CAMK_PKD_PRKD1_ST	Q9BST9	RTKN	Q15139	PRKD1	S63	Q64K	64	Missense	proximal	1	no	6.259	6.258	EPSD	ICGC	4.507	Down-regulation
CAMK_PKD_PRKD1_ST	Q9BST9	RTKN	Q15139	PRKD1	S106	R103L	103	Missense	distal	-3	no	8.272	3.344	EPSD	ICGC;COSMIC	4.507	Loss
CAMK_PKD_PRKD1_ST	Q9BST9	RTKN	Q15139	PRKD1	S106	P105T	105	Missense	proximal	-1	no	8.272	8.254	EPSD	ICGC	4.507	Down-regulation
CAMK_PKD_PRKD1_ST	Q9BST9	RTKN	Q15139	PRKD1	S108	R103L	103	Missense	distal	-5	no	3.363	5.243	EPSD	ICGC;COSMIC	4.507	Gain
CAMK_PKD_PRKD1_ST	Q9BST9	RTKN	Q15139	PRKD1	S225	A231D	231	Missense	distal	6	no	4.593	4.636	EPSD	ICGC;COSMIC	4.507	Up-regulation
CAMK_PKD_PRKD1_ST	Q12809	KCNH2	Q15139	PRKD1	S255	S255L	255	Missense	central	0	yes	6.308	0.000	EPSD	ICGC	4.507	Loss
CAMK_PKD_PRKD1_ST	Q12809	KCNH2	Q15139	PRKD1	S255	D259N	259	Missense	distal	4	no	6.308	6.297	EPSD	ICGC	4.507	Down-regulation
CAMK_PKD_PRKD1_ST	Q12809	KCNH2	Q15139	PRKD1	S283	D287N	287	Missense	distal	4	no	8.866	8.855	EPSD	ICGC;CCLE	4.507	Down-regulation
CAMK_PKD_PRKD1_ST	Q12809	KCNH2	Q15139	PRKD1	S283	D287H	287	Missense	distal	4	no	8.866	8.846	EPSD	ICGC	4.507	Down-regulation
CAMK_PKD_PRKD1_ST	Q12809	KCNH2	Q15139	PRKD1	S284	D287N	287	Missense	distal	3	no	7.574	7.586	PhosphoSitePlus	ICGC;CCLE	4.507	Up-regulation
CAMK_PKD_PRKD1_ST	Q12809	KCNH2	Q15139	PRKD1	S284	D287H	287	Missense	distal	3	no	7.574	7.599	PhosphoSitePlus	ICGC	4.507	Up-regulation
CAMK_PKD_PRKD1_ST	Q12809	KCNH2	Q15139	PRKD1	S304	P297T	297	Missense	distal	-7	no	6.686	6.630	EPSD	ICGC	4.507	Down-regulation
CAMK_PKD_PRKD1_ST	P53367	ARFIP1	Q15139	PRKD1	S28	E26K	26	Missense	proximal	-2	no	6.217	6.998	EPSD	ICGC;COSMIC	4.507	Up-regulation
CAMK_PKD_PRKD1_ST	P53367	ARFIP1	Q15139	PRKD1	S28	S28I	28	Missense	central	0	yes	6.217	0.000	EPSD	ICGC;COSMIC	4.507	Loss
CAMK_PKD_PRKD1_ST	P05549	TFAP2A	Q15139	PRKD1	S187	S185F	185	Missense	proximal	-2	no	6.466	4.912	EPSD	ICGC;COSMIC	4.507	Down-regulation
CAMK_PKD_PRKD1_ST	P05549	TFAP2A	Q15139	PRKD1	S187	S185C	185	Missense	proximal	-2	no	6.466	5.702	EPSD	ICGC;COSMIC	4.507	Down-regulation
CAMK_PKD_PRKD1_ST	Q13671	RIN1	Q15139	PRKD1	S210	Q205H	205	Missense	distal	-5	no	4.763	5.354	EPSD	ICGC;COSMIC	4.507	Up-regulation
CAMK_PKD_PRKD1_ST	Q13671	RIN1	Q15139	PRKD1	S310	P303H	303	Missense	distal	-7	no	5.000	5.030	EPSD	ICGC	4.507	Up-regulation
CAMK_PKD_PRKD1_ST	Q13671	RIN1	Q15139	PRKD1	S310	D315E	315	Missense	distal	5	no	5.000	5.061	EPSD	ICGC	4.507	Up-regulation
CAMK_PKD_PRKD1_ST	Q13671	RIN1	Q15139	PRKD1	S351	S351N	351	Missense	central	0	yes	9.466	0.000	PhosphoSitePlus;EPSD	ICGC;COSMIC	4.507	Loss
CAMK_PKD_PRKD1_ST	Q13671	RIN1	Q15139	PRKD1	T695	L693M	693	Missense	proximal	-2	no	4.902	5.806	EPSD	ICGC;COSMIC	4.507	Up-regulation
CAMK_PKD_PRKD1_ST	Q13671	RIN1	Q15139	PRKD1	T695	V700I	700	Missense	distal	5	no	4.902	4.899	EPSD	ICGC;COSMIC	4.507	Down-regulation
CAMK_PKD_PRKD1_ST	P16144	ITGB4	Q15139	PRKD1	S368	R367C	367	Missense	proximal	-1	no	6.506	6.314	EPSD	ICGC;COSMIC	4.507	Down-regulation
CAMK_PKD_PRKD1_ST	P16144	ITGB4	Q15139	PRKD1	S368	R373L	373	Missense	distal	5	no	6.506	6.429	EPSD	ICGC	4.507	Down-regulation
CAMK_PKD_PRKD1_ST	P16144	ITGB4	Q15139	PRKD1	S397	K392E	392	Missense	distal	-5	no	4.644	4.499	EPSD	ICGC;COSMIC	4.507	Loss
CAMK_PKD_PRKD1_ST	P16144	ITGB4	Q15139	PRKD1	S397	R402Q	402	Missense	distal	5	no	4.644	4.621	EPSD	ICGC	4.507	Down-regulation
CAMK_PKD_PRKD1_ST	P16144	ITGB4	Q15139	PRKD1	S397	R402L	402	Missense	distal	5	no	4.644	4.566	EPSD	ICGC;COSMIC	4.507	Down-regulation
CAMK_PKD_PRKD1_ST	P16144	ITGB4	Q15139	PRKD1	S397	G396W	396	Missense	proximal	-1	no	4.644	4.664	EPSD	ICGC	4.507	Up-regulation
CAMK_PKD_PRKD1_ST	P16144	ITGB4	Q15139	PRKD1	S397	T395N	395	Missense	proximal	-2	no	4.644	3.433	EPSD	ICGC	4.507	Loss
CAMK_PKD_PRKD1_ST	P16144	ITGB4	Q15139	PRKD1	T829	R826L	826	Missense	distal	-3	no	6.419	1.491	EPSD	ICGC	4.507	Loss
CAMK_PKD_PRKD1_ST	P16144	ITGB4	Q15139	PRKD1	T829	R826H	826	Missense	distal	-3	no	6.419	2.432	EPSD	ICGC	4.507	Loss
CAMK_PKD_PRKD1_ST	P16144	ITGB4	Q15139	PRKD1	S893	R892C	892	Missense	proximal	-1	no	7.001	6.809	EPSD	ICGC	4.507	Down-regulation
CAMK_PKD_PRKD1_ST	P16144	ITGB4	Q15139	PRKD1	S1069	V1067A	1067	Missense	proximal	-2	no	2.598	4.754	EPSD	ICGC	4.507	Gain
CAMK_PKD_PRKD1_ST	P16144	ITGB4	Q15139	PRKD1	S1140	H1144N	1144	Missense	distal	4	no	5.892	5.901	EPSD	ICGC;COSMIC	4.507	Up-regulation
CAMK_PKD_PRKD1_ST	P16144	ITGB4	Q15139	PRKD1	S1325	P1320L	1320	Missense	distal	-5	no	5.650	8.496	EPSD	ICGC;COSMIC	4.507	Up-regulation
CAMK_PKD_PRKD1_ST	P16144	ITGB4	Q15139	PRKD1	T1434	S1428L	1428	Missense	distal	-6	no	7.120	7.087	EPSD	ICGC;COSMIC	4.507	Down-regulation
CAMK_PKD_PRKD1_ST	P16144	ITGB4	Q15139	PRKD1	T1721	P1726L	1726	Missense	distal	5	no	5.259	5.248	EPSD	ICGC	4.507	Down-regulation
CAMK_PKD_PRKD1_ST	P16144	ITGB4	Q15139	PRKD1	S1791	T1793A	1793	Missense	proximal	2	no	5.362	5.470	EPSD	ICGC;COSMIC	4.507	Up-regulation
CAMK_PKD_PRKD1_ST	P16144	ITGB4	Q15139	PRKD1	T1797	T1793A	1793	Missense	distal	-4	no	7.128	7.133	EPSD	ICGC;COSMIC	4.507	Up-regulation
CAMK_PKD_PRKD1_ST	P02686	MBP	Q15139	PRKD1	S26	N22K	22	Missense	distal	-4	no	5.290	5.296	EPSD	ICGC;COSMIC	4.507	Up-regulation
CAMK_PKD_PRKD1_ST	P02686	MBP	Q15139	PRKD1	S26	N31K	31	Missense	distal	5	no	5.290	5.315	EPSD	ICGC;COSMIC	4.507	Up-regulation
CAMK_PKD_PRKD1_ST	P02686	MBP	Q15139	PRKD1	S40	G47S	47	Missense	distal	7	no	8.257	8.258	EPSD	ICGC;COSMIC;CCLE	4.507	Up-regulation
CAMK_PKD_PRKD1_ST	P02686	MBP	Q15139	PRKD1	S40	F46L	46	Missense	distal	6	no	8.257	8.236	EPSD	ICGC;COSMIC	4.507	Down-regulation
CAMK_PKD_PRKD1_ST	P02686	MBP	Q15139	PRKD1	S40	G47R	47	Missense	distal	7	no	8.257	8.258	EPSD	ICGC;COSMIC	4.507	Up-regulation
CAMK_PKD_PRKD1_ST	P02686	MBP	Q15139	PRKD1	T154	D156N	156	Missense	proximal	2	no	4.763	4.809	EPSD	ICGC;COSMIC	4.507	Up-regulation
CAMK_PKD_PRKD1_ST	O95863	SNAI1	Q15139	PRKD1	S11	D12Y	12	Missense	proximal	1	no	10.069	10.068	PhosphoSitePlus	ICGC;COSMIC	4.507	Down-regulation
CAMK_PKD_PRKD1_ST	O95863	SNAI1	Q15139	PRKD1	S11	R15L	15	Missense	distal	4	no	10.069	10.077	PhosphoSitePlus	ICGC;COSMIC	4.507	Up-regulation
CAMK_PKD_PRKD1_ST	O95863	SNAI1	Q15139	PRKD1	S119	V118A	118	Missense	proximal	-1	no	4.474	4.653	EPSD	ICGC;COSMIC	4.507	Gain
CAMK_PKD_PRKD1_ST	O95863	SNAI1	Q15139	PRKD1	S119	E124A	124	Missense	distal	5	no	4.474	4.532	EPSD	ICGC;COSMIC	4.507	Gain
CAMK_PKD_PRKD1_ST	O95863	SNAI1	Q15139	PRKD1	T203	F208L	208	Missense	distal	5	no	5.387	5.441	EPSD	ICGC;COSMIC	4.507	Up-regulation
CAMK_PKD_PRKD1_ST	O95863	SNAI1	Q15139	PRKD1	S246	R243W	243	Missense	distal	-3	no	6.585	1.212	EPSD	ICGC;COSMIC	4.507	Loss
CAMK_PKD_PRKD1_ST	P22059	OSBP	Q15139	PRKD1	T129	T129P	129	Missense	central	0	yes	5.434	0.000	EPSD	ICGC	4.507	Loss
CAMK_PKD_PRKD1_ST	P22059	OSBP	Q15139	PRKD1	T174	A179P	179	Missense	distal	5	no	4.552	4.484	EPSD	ICGC	4.507	Loss
CAMK_PKD_PRKD1_ST	P22059	OSBP	Q15139	PRKD1	T174	R169Q	169	Missense	distal	-5	no	4.552	3.838	EPSD	ICGC;COSMIC	4.507	Loss
CAMK_PKD_PRKD1_ST	P22059	OSBP	Q15139	PRKD1	S215	E219K	219	Missense	distal	4	no	7.306	7.305	EPSD	ICGC;COSMIC	4.507	Down-regulation
CAMK_PKD_PRKD1_ST	P22059	OSBP	Q15139	PRKD1	S216	E219K	219	Missense	distal	3	no	4.528	4.527	EPSD	ICGC;COSMIC	4.507	Down-regulation
CAMK_PKD_PRKD1_ST	P22059	OSBP	Q15139	PRKD1	S269	A271S	271	Missense	proximal	2	no	7.581	7.541	EPSD	ICGC;COSMIC	4.507	Down-regulation
CAMK_PKD_PRKD1_ST	P22059	OSBP	Q15139	PRKD1	S269	A262D	262	Missense	distal	-7	no	7.581	7.048	EPSD	ICGC	4.507	Down-regulation
CAMK_PKD_PRKD1_ST	P22059	OSBP	Q15139	PRKD1	T377	T377I	377	Missense	central	0	yes	4.972	0.000	EPSD	ICGC;COSMIC	4.507	Loss
CAMK_PKD_PRKD1_ST	P22059	OSBP	Q15139	PRKD1	S379	T377I	377	Missense	proximal	-2	no	6.164	5.021	EPSD	ICGC;COSMIC	4.507	Down-regulation
CAMK_PKD_PRKD1_ST	P22059	OSBP	Q15139	PRKD1	T628	R621W	621	Missense	distal	-7	no	7.439	6.755	EPSD	ICGC;COSMIC	4.507	Down-regulation
CAMK_PKD_PRKD1_ST	P22059	OSBP	Q15139	PRKD1	T628	V623I	623	Missense	distal	-5	no	7.439	7.316	EPSD	ICGC;COSMIC	4.507	Down-regulation
CAMK_PKD_PRKD1_ST	P50552	VASP	Q15139	PRKD1	S157	V156F	156	Missense	proximal	-1	no	9.857	9.738	PhosphoSitePlus;EPSD	ICGC	4.507	Down-regulation
CAMK_PKD_PRKD1_ST	P50552	VASP	Q15139	PRKD1	S157	I152M	152	Missense	distal	-5	no	9.857	9.887	PhosphoSitePlus;EPSD	ICGC;COSMIC	4.507	Up-regulation
CAMK_PKD_PRKD1_ST	P50552	VASP	Q15139	PRKD1	S157	S157Y	157	Missense	central	0	yes	9.857	0.000	PhosphoSitePlus;EPSD	ICGC;COSMIC	4.507	Loss
CAMK_PKD_PRKD1_ST	P50552	VASP	Q15139	PRKD1	S255	A250T	250	Missense	distal	-5	no	4.550	3.883	EPSD	ICGC	4.507	Loss
CAMK_PKD_PRKD1_ST	P50552	VASP	Q15139	PRKD1	S255	A253G	253	Missense	proximal	-2	no	4.550	2.808	EPSD	ICGC;COSMIC	4.507	Loss
CAMK_PKD_PRKD1_ST	P50552	VASP	Q15139	PRKD1	T278	G281V	281	Missense	distal	3	no	4.499	4.512	EPSD	ICGC;COSMIC	4.507	Gain
CAMK_PKD_PRKD1_ST	P50552	VASP	Q15139	PRKD1	S322	K321N	321	Missense	proximal	-1	no	9.307	9.210	EPSD;PhosphoSitePlus	ICGC	4.507	Down-regulation
CAMK_PKD_PRKD1_ST	P50552	VASP	Q15139	PRKD1	S324	K321N	321	Missense	distal	-3	no	5.019	2.108	EPSD	ICGC	4.507	Loss
CAMK_PKD_PRKD1_ST	O14558	HSPB6	Q15139	PRKD1	S59	P63H	63	Missense	distal	4	no	7.550	7.542	EPSD	ICGC;COSMIC	4.507	Down-regulation
CAMK_PKD_PRKD1_ST	O14558	HSPB6	Q15139	PRKD1	S59	A65T	65	Missense	distal	6	no	7.550	7.581	EPSD	ICGC;COSMIC	4.507	Up-regulation
CAMK_PKD_PRKD1_ST	O14558	HSPB6	Q15139	PRKD1	S59	Y54C	54	Missense	distal	-5	no	7.550	8.349	EPSD	ICGC;COSMIC	4.507	Up-regulation
CAMK_PKD_PRKD1_ST	Q92918	MAP4K1	Q15139	PRKD1	S171	P176T	176	Missense	distal	5	no	12.724	12.714	PhosphoSitePlus	ICGC;GDSC;CCLE	4.507	Down-regulation
CAMK_PKD_PRKD1_ST	Q92918	MAP4K1	Q15139	PRKD1	S320	H322R	322	Missense	proximal	2	no	4.490	4.528	EPSD	ICGC	4.507	Gain
CAMK_PKD_PRKD1_ST	Q92918	MAP4K1	Q15139	PRKD1	S324	H322R	322	Missense	proximal	-2	no	3.988	5.935	EPSD	ICGC	4.507	Gain
CAMK_PKD_PRKD1_ST	Q92918	MAP4K1	Q15139	PRKD1	S325	H322R	322	Missense	distal	-3	no	4.519	8.506	EPSD	ICGC	4.507	Up-regulation
CAMK_PKD_PRKD1_ST	Q92918	MAP4K1	Q15139	PRKD1	S326	H322R	322	Missense	distal	-4	no	6.803	6.808	EPSD	ICGC	4.507	Up-regulation
CAMK_PKD_PRKD1_ST	Q92918	MAP4K1	Q15139	PRKD1	S368	S367N	367	Missense	proximal	-1	no	7.175	7.016	EPSD	ICGC;COSMIC	4.507	Down-regulation
CAMK_PKD_PRKD1_ST	Q92918	MAP4K1	Q15139	PRKD1	S407	P406Q	406	Missense	proximal	-1	no	6.713	6.767	EPSD	ICGC	4.507	Up-regulation
CAMK_PKD_PRKD1_ST	Q92918	MAP4K1	Q15139	PRKD1	S407	G412V	412	Missense	distal	5	no	6.713	6.777	EPSD	ICGC;COSMIC	4.507	Up-regulation
CAMK_PKD_PRKD1_ST	Q92918	MAP4K1	Q15139	PRKD1	S430	R427W	427	Missense	distal	-3	no	8.323	2.951	EPSD	ICGC;COSMIC;GDSC;CCLE	4.507	Loss
CAMK_PKD_PRKD1_ST	Q92918	MAP4K1	Q15139	PRKD1	S454	S447R	447	Missense	distal	-7	no	5.484	5.765	EPSD	ICGC	4.507	Up-regulation
CAMK_PKD_PRKD1_ST	Q92918	MAP4K1	Q15139	PRKD1	S454	S457P	457	Missense	distal	3	no	5.484	5.474	EPSD	ICGC;COSMIC	4.507	Down-regulation
TK_PDGFR_KIT_Y	P10721	KIT	P10721	KIT	Y547	M541L	541	Missense	distal	-6	no	3.906	3.929	EPSD;PhosphoSitePlus	ICGC;COSMIC	1.639	Up-regulation
TK_PDGFR_KIT_Y	P10721	KIT	P10721	KIT	Y553	V560D	560	Missense	distal	7	no	3.485	3.456	PhosphoSitePlus;EPSD	ICGC;COSMIC	1.639	Down-regulation
TK_PDGFR_KIT_Y	P10721	KIT	P10721	KIT	Y553	K558N	558	Missense	distal	5	no	3.485	3.480	PhosphoSitePlus;EPSD	ICGC;COSMIC	1.639	Down-regulation
TK_PDGFR_KIT_Y	P10721	KIT	P10721	KIT	Y568	Y568S	568	Missense	central	0	yes	3.400	0.000	EPSD;PhosphoSitePlus	ICGC;COSMIC	1.639	Loss
TK_PDGFR_KIT_Y	P10721	KIT	P10721	KIT	Y568	T574A	574	Missense	distal	6	no	3.400	3.384	EPSD;PhosphoSitePlus	ICGC;COSMIC	1.639	Down-regulation
TK_PDGFR_KIT_Y	P10721	KIT	P10721	KIT	Y570	Y568S	568	Missense	proximal	-2	no	3.527	3.533	EPSD;PhosphoSitePlus	ICGC;COSMIC	1.639	Up-regulation
TK_PDGFR_KIT_Y	P10721	KIT	P10721	KIT	Y570	T574A	574	Missense	distal	4	no	3.527	3.751	EPSD;PhosphoSitePlus	ICGC;COSMIC	1.639	Up-regulation
TK_PDGFR_KIT_Y	P10721	KIT	P10721	KIT	Y570	P577L	577	Missense	distal	7	no	3.527	3.525	EPSD;PhosphoSitePlus	ICGC;COSMIC	1.639	Down-regulation
TK_PDGFR_KIT_Y	P10721	KIT	P10721	KIT	Y578	Y578S	578	Missense	central	0	yes	1.744	0.000	EPSD	ICGC;COSMIC	1.639	Loss
TK_PDGFR_KIT_Y	P10721	KIT	P10721	KIT	Y578	T574A	574	Missense	distal	-4	no	1.744	1.721	EPSD	ICGC;COSMIC	1.639	Down-regulation
TK_PDGFR_KIT_Y	P10721	KIT	P10721	KIT	Y578	P577L	577	Missense	proximal	-1	no	1.744	1.646	EPSD	ICGC;COSMIC	1.639	Down-regulation
TK_PDGFR_KIT_Y	P10721	KIT	P10721	KIT	Y578	W582L	582	Missense	distal	4	no	1.744	1.829	EPSD	ICGC;COSMIC	1.639	Up-regulation
TK_PDGFR_KIT_Y	P10721	KIT	P10721	KIT	Y703	A701G	701	Missense	proximal	-2	no	3.477	3.475	EPSD;PhosphoSitePlus	ICGC;COSMIC	1.639	Down-regulation
TK_PDGFR_KIT_Y	P10721	KIT	P10721	KIT	Y721	M722I	722	Missense	proximal	1	no	3.319	3.289	EPSD;PhosphoSitePlus	ICGC;COSMIC	1.639	Down-regulation
TK_PDGFR_KIT_Y	P10721	KIT	P10721	KIT	Y823	V825F	825	Missense	proximal	2	no	4.730	4.718	EPSD;PhosphoSitePlus	ICGC	1.639	Down-regulation
TK_PDGFR_KIT_Y	P10721	KIT	P10721	KIT	Y823	D820Y	820	Missense	distal	-3	no	4.730	4.698	EPSD;PhosphoSitePlus	ICGC;COSMIC	1.639	Down-regulation
TK_PDGFR_KIT_Y	Q9GZY6	LAT2	P10721	KIT	Y110	S106P	106	Missense	distal	-4	no	4.234	4.123	PhosphoSitePlus;EPSD	ICGC;COSMIC	1.639	Down-regulation
TK_PDGFR_KIT_Y	Q9GZY6	LAT2	P10721	KIT	Y110	A115S	115	Missense	distal	5	no	4.234	4.197	PhosphoSitePlus;EPSD	ICGC	1.639	Down-regulation
TK_PDGFR_KIT_Y	Q9GZY6	LAT2	P10721	KIT	Y118	A115S	115	Missense	distal	-3	no	3.690	3.740	EPSD;PhosphoSitePlus	ICGC	1.639	Up-regulation
Other_PEK_PKR_EIF2AK2_ST	P19525	EIF2AK2	P19525	EIF2AK2	S83	E78D	78	Missense	distal	-5	no	102.539	104.015	EPSD;PhosphoSitePlus	ICGC	66.906	Up-regulation
Other_PEK_PKR_EIF2AK2_ST	P19525	EIF2AK2	P19525	EIF2AK2	T88	G95A	95	Missense	distal	7	no	116.907	105.642	EPSD;PhosphoSitePlus	ICGC;COSMIC	66.906	Down-regulation
Other_PEK_PKR_EIF2AK2_ST	P19525	EIF2AK2	P19525	EIF2AK2	T89	G95A	95	Missense	distal	6	no	104.941	85.188	EPSD;PhosphoSitePlus	ICGC;COSMIC	66.906	Down-regulation
Other_PEK_PKR_EIF2AK2_ST	P19525	EIF2AK2	P19525	EIF2AK2	T90	G95A	95	Missense	distal	5	no	96.407	93.244	EPSD;PhosphoSitePlus	ICGC;COSMIC	66.906	Down-regulation
Other_PEK_PKR_EIF2AK2_ST	P19525	EIF2AK2	P19525	EIF2AK2	S242	L243S	243	Missense	proximal	1	no	110.237	109.517	PhosphoSitePlus;EPSD	ICGC;COSMIC	66.906	Down-regulation
Other_PEK_PKR_EIF2AK2_ST	P19525	EIF2AK2	P19525	EIF2AK2	T255	R262K	262	Missense	distal	7	no	117.648	111.954	EPSD;PhosphoSitePlus	ICGC;COSMIC	66.906	Down-regulation
Other_PEK_PKR_EIF2AK2_ST	P19525	EIF2AK2	P19525	EIF2AK2	T255	D260E	260	Missense	distal	5	no	117.648	115.547	EPSD;PhosphoSitePlus	ICGC	66.906	Down-regulation
Other_PEK_PKR_EIF2AK2_ST	P19525	EIF2AK2	P19525	EIF2AK2	T255	P250T	250	Missense	distal	-5	no	117.648	116.089	EPSD;PhosphoSitePlus	ICGC	66.906	Down-regulation
Other_PEK_PKR_EIF2AK2_ST	P19525	EIF2AK2	P19525	EIF2AK2	T258	R262K	262	Missense	distal	4	no	106.644	110.549	EPSD;PhosphoSitePlus	ICGC;COSMIC	66.906	Up-regulation
Other_PEK_PKR_EIF2AK2_ST	P19525	EIF2AK2	P19525	EIF2AK2	T258	D260E	260	Missense	proximal	2	no	106.644	106.216	EPSD;PhosphoSitePlus	ICGC	66.906	Down-regulation
Other_PEK_PKR_EIF2AK2_ST	P19525	EIF2AK2	P19525	EIF2AK2	T446	T451N	451	Missense	distal	5	no	93.940	92.702	EPSD;PhosphoSitePlus	ICGC	66.906	Down-regulation
Other_PEK_PKR_EIF2AK2_ST	P19525	EIF2AK2	P19525	EIF2AK2	T451	T451N	451	Missense	central	0	yes	104.200	0.000	EPSD;PhosphoSitePlus	ICGC	66.906	Loss
Other_PEK_PKR_EIF2AK2_ST	P05198	EIF2S1	P19525	EIF2AK2	S110	A116S	116	Missense	distal	6	no	62.753	68.318	EPSD	ICGC	66.906	Gain
Other_PEK_PKR_EIF2AK2_ST	P10636	MAPT	P19525	EIF2AK2	T111	D116E	116	Missense	distal	5	no	71.982	69.882	EPSD	ICGC;COSMIC	66.906	Down-regulation
Other_PEK_PKR_EIF2AK2_ST	P10636	MAPT	P19525	EIF2AK2	T123	D116E	116	Missense	distal	-7	no	83.137	84.260	EPSD	ICGC;COSMIC	66.906	Up-regulation
Other_PEK_PKR_EIF2AK2_ST	P10636	MAPT	P19525	EIF2AK2	T123	E127K	127	Missense	distal	4	no	83.137	83.624	EPSD	ICGC	66.906	Up-regulation
Other_PEK_PKR_EIF2AK2_ST	P06493	CDK1	P19525	EIF2AK2	S46	R50L	50	Missense	distal	4	no	97.058	97.366	EPSD	ICGC;COSMIC	66.906	Up-regulation
Other_PEK_PKR_EIF2AK2_ST	P06493	CDK1	P19525	EIF2AK2	S46	P45S	45	Missense	proximal	-1	no	97.058	96.340	EPSD	ICGC	66.906	Down-regulation
Other_PEK_PKR_EIF2AK2_ST	Q15172	PPP2R5A	P19525	EIF2AK2	S28	D22G	22	Missense	distal	-6	no	90.252	67.754	PhosphoSitePlus	ICGC;COSMIC	66.906	Down-regulation
Other_PEK_PKR_EIF2AK2_ST	Q15172	PPP2R5A	P19525	EIF2AK2	S28	D22H	22	Missense	distal	-6	no	90.252	83.337	PhosphoSitePlus	ICGC	66.906	Down-regulation
Other_PEK_PKR_EIF2AK2_ST	Q15172	PPP2R5A	P19525	EIF2AK2	T281	F288L	288	Missense	distal	7	no	66.472	67.641	EPSD	ICGC;COSMIC	66.906	Gain
Other_PEK_PKR_EIF2AK2_ST	P04637	TP53	P19525	EIF2AK2	S99	Q100K	100	Missense	proximal	1	no	65.275	67.991	EPSD	ICGC;COSMIC	66.906	Gain
Other_PEK_PKR_EIF2AK2_ST	P04637	TP53	P19525	EIF2AK2	S149	P142H	142	Missense	distal	-7	no	69.762	69.298	EPSD	ICGC;COSMIC	66.906	Down-regulation
Other_PEK_PKR_EIF2AK2_ST	P04637	TP53	P19525	EIF2AK2	S149	R156L	156	Missense	distal	7	no	69.762	69.151	EPSD	ICGC;COSMIC	66.906	Down-regulation
Other_PEK_PKR_EIF2AK2_ST	P04637	TP53	P19525	EIF2AK2	S149	L145Q	145	Missense	distal	-4	no	69.762	67.860	EPSD	ICGC;COSMIC	66.906	Down-regulation
Other_PEK_PKR_EIF2AK2_ST	P04637	TP53	P19525	EIF2AK2	S149	P152R	152	Missense	distal	3	no	69.762	68.420	EPSD	ICGC;COSMIC	66.906	Down-regulation
Other_PEK_PKR_EIF2AK2_ST	P04637	TP53	P19525	EIF2AK2	S149	G154S	154	Missense	distal	5	no	69.762	68.380	EPSD	ICGC;COSMIC	66.906	Down-regulation
Other_PEK_PKR_EIF2AK2_ST	P04637	TP53	P19525	EIF2AK2	S149	P151F	151	Missense	proximal	2	no	69.762	69.777	EPSD	ICGC;COSMIC	66.906	Up-regulation
Other_PEK_PKR_EIF2AK2_ST	P04637	TP53	P19525	EIF2AK2	S149	V147G	147	Missense	proximal	-2	no	69.762	65.262	EPSD	ICGC;COSMIC;GDSC;CCLE	66.906	Loss
TK_Eph_EPHA2_Y	P29317	EPHA2	P29317	EPHA2	Y575	V574I	574	Missense	proximal	-1	no	3.036	2.770	EPSD;PhosphoSitePlus	ICGC;COSMIC	1.229	Down-regulation
TK_Eph_EPHA2_Y	P29317	EPHA2	P29317	EPHA2	Y575	Y575C	575	Missense	central	0	yes	3.036	0.000	EPSD;PhosphoSitePlus	ICGC	1.229	Loss
TK_Eph_EPHA2_Y	P29317	EPHA2	P29317	EPHA2	Y588	T587A	587	Missense	proximal	-1	no	2.253	2.058	EPSD;PhosphoSitePlus	ICGC;COSMIC	1.229	Down-regulation
TK_Eph_EPHA2_Y	P29317	EPHA2	P29317	EPHA2	Y588	K586N	586	Missense	proximal	-2	no	2.253	2.247	EPSD;PhosphoSitePlus	ICGC;COSMIC	1.229	Down-regulation
TK_Eph_EPHA2_Y	P29317	EPHA2	P29317	EPHA2	Y588	P591S	591	Missense	distal	3	no	2.253	2.144	EPSD;PhosphoSitePlus	ICGC;COSMIC	1.229	Down-regulation
TK_Eph_EPHA2_Y	P29317	EPHA2	P29317	EPHA2	Y594	T587A	587	Missense	distal	-7	no	3.437	3.324	EPSD;PhosphoSitePlus	ICGC;COSMIC	1.229	Down-regulation
TK_Eph_EPHA2_Y	P29317	EPHA2	P29317	EPHA2	Y594	P597H	597	Missense	distal	3	no	3.437	3.388	EPSD;PhosphoSitePlus	ICGC;COSMIC	1.229	Down-regulation
TK_Eph_EPHA2_Y	P29317	EPHA2	P29317	EPHA2	Y594	P591S	591	Missense	distal	-3	no	3.437	2.990	EPSD;PhosphoSitePlus	ICGC;COSMIC	1.229	Down-regulation
TK_Eph_EPHA2_Y	P29317	EPHA2	P29317	EPHA2	Y628	E626K	626	Missense	proximal	-2	no	2.273	2.231	EPSD;PhosphoSitePlus	ICGC;COSMIC	1.229	Down-regulation
TK_Eph_EPHA2_Y	P29317	EPHA2	P29317	EPHA2	Y628	G630S	630	Missense	proximal	2	no	2.273	2.274	EPSD;PhosphoSitePlus	ICGC;COSMIC	1.229	Up-regulation
TK_Eph_EPHA2_Y	P29317	EPHA2	P29317	EPHA2	Y628	A621E	621	Missense	distal	-7	no	2.273	2.334	EPSD;PhosphoSitePlus	ICGC	1.229	Up-regulation
TK_Eph_EPHA2_Y	P29317	EPHA2	P29317	EPHA2	Y628	Y628F	628	Missense	central	0	yes	2.273	0.000	EPSD;PhosphoSitePlus	ICGC;COSMIC	1.229	Loss
TK_Eph_EPHA2_Y	P29317	EPHA2	P29317	EPHA2	Y694	A699T	699	Missense	distal	5	no	2.212	2.172	EPSD;PhosphoSitePlus	ICGC;COSMIC	1.229	Down-regulation
TK_Eph_EPHA2_Y	P29317	EPHA2	P29317	EPHA2	Y694	T692N	692	Missense	proximal	-2	no	2.212	2.234	EPSD;PhosphoSitePlus	ICGC	1.229	Up-regulation
TK_Eph_EPHA2_Y	P29317	EPHA2	P29317	EPHA2	Y735	D739Y	739	Missense	distal	4	no	3.040	2.984	EPSD;PhosphoSitePlus	ICGC;COSMIC	1.229	Down-regulation
TK_Eph_EPHA2_Y	P29317	EPHA2	P29317	EPHA2	Y735	L730M	730	Missense	distal	-5	no	3.040	3.053	EPSD;PhosphoSitePlus	ICGC;COSMIC	1.229	Up-regulation
TK_Eph_EPHA2_Y	P29317	EPHA2	P29317	EPHA2	Y772	G777C	777	Missense	distal	5	no	2.847	2.821	PhosphoSitePlus;EPSD	ICGC;COSMIC	1.229	Down-regulation
TK_Eph_EPHA2_Y	P29317	EPHA2	P29317	EPHA2	Y772	E765G	765	Missense	distal	-7	no	2.847	2.767	PhosphoSitePlus;EPSD	ICGC	1.229	Down-regulation
TK_Eph_EPHA2_Y	P29317	EPHA2	P29317	EPHA2	Y921	M926K	926	Missense	distal	5	no	2.307	2.290	EPSD;PhosphoSitePlus	ICGC;COSMIC	1.229	Down-regulation
TK_Eph_EPHA2_Y	P29317	EPHA2	P29317	EPHA2	Y960	H954N	954	Missense	distal	-6	no	1.938	1.948	EPSD;PhosphoSitePlus	ICGC	1.229	Up-regulation
TK_Eph_EPHA2_Y	P29317	EPHA2	P29317	EPHA2	Y960	R957C	957	Missense	distal	-3	no	1.938	1.869	EPSD;PhosphoSitePlus	ICGC;COSMIC	1.229	Down-regulation
CAMK_CAMKL_LKB_STK11_ST	P60484	PTEN	Q15831	STK11	T321	D324Y	324	Missense	distal	3	no	21.450	17.019	EPSD	ICGC	16.403	Down-regulation
CAMK_CAMKL_LKB_STK11_ST	P60484	PTEN	Q15831	STK11	T321	D324N	324	Missense	distal	3	no	21.450	16.389	EPSD	ICGC	16.403	Loss
CAMK_CAMKL_LKB_STK11_ST	P60484	PTEN	Q15831	STK11	T350	L345Q	345	Missense	distal	-5	no	16.875	17.717	EPSD	ICGC;COSMIC	16.403	Up-regulation
CAMK_CAMKL_LKB_STK11_ST	P60484	PTEN	Q15831	STK11	T350	L345M	345	Missense	distal	-5	no	16.875	17.685	EPSD	ICGC;COSMIC	16.403	Up-regulation
CAMK_CAMKL_LKB_STK11_ST	P60484	PTEN	Q15831	STK11	T350	L345P	345	Missense	distal	-5	no	16.875	19.417	EPSD	ICGC;COSMIC	16.403	Up-regulation
CAMK_CAMKL_LKB_STK11_ST	P60484	PTEN	Q15831	STK11	T350	P354L	354	Missense	distal	4	no	16.875	17.080	EPSD	ICGC;COSMIC	16.403	Up-regulation
CAMK_CAMKL_LKB_STK11_ST	P60484	PTEN	Q15831	STK11	T363	S360R	360	Missense	distal	-3	no	25.338	25.209	EPSD	ICGC	16.403	Down-regulation
CAMK_CAMKL_LKB_STK11_ST	P60484	PTEN	Q15831	STK11	T382	E388Q	388	Missense	distal	6	no	29.208	26.656	EPSD;PhosphoSitePlus	ICGC;COSMIC	16.403	Down-regulation
CAMK_CAMKL_LKB_STK11_ST	P60484	PTEN	Q15831	STK11	T383	E388Q	388	Missense	distal	5	no	27.101	25.929	EPSD;PhosphoSitePlus	ICGC;COSMIC	16.403	Down-regulation
CAMK_CAMKL_LKB_STK11_ST	Q7RTN6	STRADA	Q15831	STK11	T419	T419A	419	Missense	central	0	yes	30.557	0.000	EPSD;PhosphoSitePlus	ICGC;COSMIC	16.403	Loss
CAMK_CAMKL_LKB_STK11_ST	Q13485	SMAD4	Q15831	STK11	T77	Q75K	75	Missense	proximal	-2	no	32.038	34.815	PhosphoSitePlus	ICGC;COSMIC	16.403	Up-regulation
CAMK_CAMKL_LKB_STK11_ST	Q13485	SMAD4	Q15831	STK11	S171	L172F	172	Missense	proximal	1	no	23.775	23.785	EPSD	ICGC	16.403	Up-regulation
CAMK_CAMKL_LKB_STK11_ST	Q13485	SMAD4	Q15831	STK11	S171	E175Q	175	Missense	distal	4	no	23.775	24.655	EPSD	ICGC;COSMIC	16.403	Up-regulation
CAMK_CAMKL_LKB_STK11_ST	P27448	MARK3	Q15831	STK11	T204	D210Y	210	Missense	distal	6	no	26.250	23.107	EPSD	ICGC;COSMIC	16.403	Down-regulation
CAMK_CAMKL_LKB_STK11_ST	P27448	MARK3	Q15831	STK11	T204	D210N	210	Missense	distal	6	no	26.250	24.256	EPSD	ICGC;COSMIC;GDSC;CCLE	16.403	Down-regulation
CAMK_CAMKL_LKB_STK11_ST	P27448	MARK3	Q15831	STK11	T204	G207C	207	Missense	distal	3	no	26.250	18.602	EPSD	ICGC;COSMIC	16.403	Down-regulation
CAMK_CAMKL_LKB_STK11_ST	P27448	MARK3	Q15831	STK11	T204	G206V	206	Missense	proximal	2	no	26.250	30.569	EPSD	ICGC	16.403	Up-regulation
CAMK_CAMKL_LKB_STK11_ST	P27448	MARK3	Q15831	STK11	T211	D210Y	210	Missense	proximal	-1	no	61.854	62.229	EPSD;PhosphoSitePlus	ICGC;COSMIC	16.403	Up-regulation
CAMK_CAMKL_LKB_STK11_ST	P27448	MARK3	Q15831	STK11	T211	D210N	210	Missense	proximal	-1	no	61.854	61.947	EPSD;PhosphoSitePlus	ICGC;COSMIC;GDSC;CCLE	16.403	Up-regulation
CAMK_CAMKL_LKB_STK11_ST	P27448	MARK3	Q15831	STK11	T211	G207C	207	Missense	distal	-4	no	61.854	61.806	EPSD;PhosphoSitePlus	ICGC;COSMIC	16.403	Down-regulation
CAMK_CAMKL_LKB_STK11_ST	P27448	MARK3	Q15831	STK11	T211	S215I	215	Missense	distal	4	no	61.854	62.205	EPSD;PhosphoSitePlus	ICGC	16.403	Up-regulation
CAMK_CAMKL_LKB_STK11_ST	P27448	MARK3	Q15831	STK11	T211	G206V	206	Missense	distal	-5	no	61.854	60.471	EPSD;PhosphoSitePlus	ICGC	16.403	Down-regulation
CAMK_CAMKL_LKB_STK11_ST	P27448	MARK3	Q15831	STK11	S215	D210Y	210	Missense	distal	-5	no	22.083	20.949	PhosphoSitePlus;EPSD	ICGC;COSMIC	16.403	Down-regulation
CAMK_CAMKL_LKB_STK11_ST	P27448	MARK3	Q15831	STK11	S215	D210N	210	Missense	distal	-5	no	22.083	20.924	PhosphoSitePlus;EPSD	ICGC;COSMIC;GDSC;CCLE	16.403	Down-regulation
CAMK_CAMKL_LKB_STK11_ST	P27448	MARK3	Q15831	STK11	S215	S215I	215	Missense	central	0	yes	22.083	0.000	PhosphoSitePlus;EPSD	ICGC	16.403	Loss
CAMK_CAMKL_LKB_STK11_ST	P27448	MARK3	Q15831	STK11	T497	R504Q	504	Missense	distal	7	no	28.512	28.469	EPSD	ICGC	16.403	Down-regulation
CAMK_CAMKL_LKB_STK11_ST	P27448	MARK3	Q15831	STK11	T497	P493T	493	Missense	distal	-4	no	28.512	28.490	EPSD	ICGC;COSMIC	16.403	Down-regulation
CAMK_CAMKL_LKB_STK11_ST	P27448	MARK3	Q15831	STK11	T514	V509F	509	Missense	distal	-5	no	25.152	25.226	EPSD	ICGC	16.403	Up-regulation
CAMK_CAMKL_LKB_STK11_ST	P27448	MARK3	Q15831	STK11	T515	V509F	509	Missense	distal	-6	no	21.939	21.966	EPSD	ICGC	16.403	Up-regulation
CAMK_CAMKL_LKB_STK11_ST	P27448	MARK3	Q15831	STK11	T574	R573Q	573	Missense	proximal	-1	no	19.679	19.743	EPSD	ICGC;COSMIC	16.403	Up-regulation
CAMK_CAMKL_LKB_STK11_ST	P27448	MARK3	Q15831	STK11	T574	R573L	573	Missense	proximal	-1	no	19.679	19.764	EPSD	ICGC;COSMIC	16.403	Up-regulation
CAMK_CAMKL_LKB_STK11_ST	Q9H093	NUAK2	Q15831	STK11	T208	C210S	210	Missense	proximal	2	no	57.217	52.530	PhosphoSitePlus	ICGC	16.403	Down-regulation
CAMK_CAMKL_LKB_STK11_ST	Q9H093	NUAK2	Q15831	STK11	T519	A516V	516	Missense	distal	-3	no	24.260	24.309	EPSD	ICGC	16.403	Up-regulation
CAMK_CAMKL_LKB_STK11_ST	Q9H093	NUAK2	Q15831	STK11	T519	A517V	517	Missense	proximal	-2	no	24.260	23.323	EPSD	ICGC	16.403	Down-regulation
CAMK_CAMKL_LKB_STK11_ST	Q9H093	NUAK2	Q15831	STK11	T519	L524M	524	Missense	distal	5	no	24.260	24.228	EPSD	ICGC	16.403	Down-regulation
CAMK_CAMKL_LKB_STK11_ST	Q9H093	NUAK2	Q15831	STK11	T519	A516E	516	Missense	distal	-3	no	24.260	24.411	EPSD	ICGC	16.403	Up-regulation
CAMK_CAMKL_LKB_STK11_ST	Q8TDC3	BRSK1	Q15831	STK11	T189	G192C	192	Missense	distal	3	no	58.183	50.535	EPSD;PhosphoSitePlus	ICGC;COSMIC	16.403	Down-regulation
CAMK_CAMKL_LKB_STK11_ST	Q8TDC3	BRSK1	Q15831	STK11	T189	V182M	182	Missense	distal	-7	no	58.183	57.949	EPSD;PhosphoSitePlus	ICGC	16.403	Down-regulation
CAMK_CAMKL_LKB_STK11_ST	Q6UUV9	CRTC1	Q15831	STK11	T163	S170F	170	Missense	distal	7	no	19.884	20.057	EPSD	ICGC;COSMIC	16.403	Up-regulation
CAMK_CAMKL_LKB_STK11_ST	Q15831	STK11	Q15831	STK11	T185	N181I	181	Missense	distal	-4	no	34.196	33.874	EPSD;PhosphoSitePlus	ICGC;COSMIC	16.403	Down-regulation
CAMK_CAMKL_LKB_STK11_ST	Q15831	STK11	Q15831	STK11	T185	N181Y	181	Missense	distal	-4	no	34.196	33.844	EPSD;PhosphoSitePlus	ICGC;COSMIC	16.403	Down-regulation
CAMK_CAMKL_LKB_STK11_ST	Q15831	STK11	Q15831	STK11	T185	G187C	187	Missense	proximal	2	no	34.196	42.431	EPSD;PhosphoSitePlus	ICGC	16.403	Up-regulation
CAMK_CAMKL_LKB_STK11_ST	Q15831	STK11	Q15831	STK11	T189	G187C	187	Missense	proximal	-2	no	36.410	40.959	EPSD;PhosphoSitePlus	ICGC	16.403	Up-regulation
CAMK_CAMKL_LKB_STK11_ST	Q15831	STK11	Q15831	STK11	T363	G370V	370	Missense	distal	7	no	33.775	33.128	EPSD;PhosphoSitePlus	ICGC;COSMIC	16.403	Down-regulation
CAMK_CAMKL_LKB_STK11_ST	Q15831	STK11	Q15831	STK11	T363	F366L	366	Missense	distal	3	no	33.775	25.267	EPSD;PhosphoSitePlus	ICGC;COSMIC	16.403	Down-regulation
CAMK_CAMKL_LKB_STK11_ST	Q15831	STK11	Q15831	STK11	T402	A397G	397	Missense	distal	-5	no	28.705	30.503	EPSD;PhosphoSitePlus	ICGC;COSMIC	16.403	Up-regulation
CAMK_CAMKL_LKB_STK11_ST	Q15831	STK11	Q15831	STK11	S428	R425L	425	Missense	distal	-3	no	18.801	19.002	PhosphoSitePlus;EPSD	ICGC	16.403	Up-regulation
CAMK_CAMKL_LKB_STK11_ST	P57059	SIK1	Q15831	STK11	S186	E193K	193	Missense	distal	7	no	19.794	19.094	EPSD	ICGC	16.403	Down-regulation
CAMK_CAMKL_LKB_STK11_ST	P57059	SIK1	Q15831	STK11	S545	P541S	541	Missense	distal	-4	no	17.198	16.708	EPSD	ICGC;COSMIC	16.403	Down-regulation
CAMK_CAMKL_LKB_STK11_ST	P57059	SIK1	Q15831	STK11	S545	T549I	549	Missense	distal	4	no	17.198	16.937	EPSD	ICGC;COSMIC;GDSC;CCLE	16.403	Down-regulation
CAMK_CAMKL_LKB_STK11_ST	P57059	SIK1	Q15831	STK11	S545	V551G	551	Missense	distal	6	no	17.198	17.764	EPSD	ICGC	16.403	Up-regulation
CAMK_CAMKL_LKB_STK11_ST	P57059	SIK1	Q15831	STK11	S545	A539T	539	Missense	distal	-6	no	17.198	17.138	EPSD	ICGC	16.403	Down-regulation
CAMK_CAMKL_LKB_STK11_ST	O14744	PRMT5	Q15831	STK11	T194	L195F	195	Missense	proximal	1	no	16.757	16.767	EPSD	ICGC;COSMIC	16.403	Up-regulation
CAMK_CAMKL_LKB_STK11_ST	O60285	NUAK1	Q15831	STK11	T211	K205N	205	Missense	distal	-6	no	57.079	57.086	PhosphoSitePlus	ICGC;COSMIC	16.403	Up-regulation
CAMK_CAMKL_LKB_STK11_ST	O60285	NUAK1	Q15831	STK11	S267	G268R	268	Missense	proximal	1	no	20.927	20.918	EPSD	ICGC;COSMIC	16.403	Down-regulation
CAMK_CAMKL_LKB_STK11_ST	O60285	NUAK1	Q15831	STK11	S267	S267R	267	Missense	central	0	yes	20.927	0.000	EPSD	ICGC	16.403	Loss
CAMK_CAMKL_LKB_STK11_ST	O60285	NUAK1	Q15831	STK11	S542	P543R	543	Missense	proximal	1	no	24.505	24.504	EPSD	ICGC;COSMIC	16.403	Down-regulation
CAMK_CAMKL_LKB_STK11_ST	O60285	NUAK1	Q15831	STK11	S542	A539D	539	Missense	distal	-3	no	24.505	24.636	EPSD	ICGC	16.403	Up-regulation
CAMK_CAMKL_LKB_STK11_ST	O60285	NUAK1	Q15831	STK11	T547	P543R	543	Missense	distal	-4	no	18.532	17.923	EPSD	ICGC;COSMIC	16.403	Down-regulation
CAMK_CAMKL_LKB_STK11_ST	O60285	NUAK1	Q15831	STK11	S550	P543R	543	Missense	distal	-7	no	17.108	16.704	EPSD	ICGC;COSMIC	16.403	Down-regulation
CAMK_CAMKL_LKB_STK11_ST	O60285	NUAK1	Q15831	STK11	S550	V556A	556	Missense	distal	6	no	17.108	17.223	EPSD	ICGC	16.403	Up-regulation
CAMK_CAMKL_LKB_STK11_ST	Q13153	PAK1	Q15831	STK11	T22	G27S	27	Missense	distal	5	no	18.264	18.356	EPSD	ICGC;COSMIC	16.403	Up-regulation
CAMK_CAMKL_LKB_STK11_ST	Q13153	PAK1	Q15831	STK11	T22	P16L	16	Missense	distal	-6	no	18.264	18.326	EPSD	ICGC;COSMIC	16.403	Up-regulation
CAMK_CAMKL_LKB_STK11_ST	Q13153	PAK1	Q15831	STK11	T22	T22N	22	Missense	central	0	yes	18.264	0.000	EPSD	ICGC	16.403	Loss
CAMK_CAMKL_LKB_STK11_ST	Q13153	PAK1	Q15831	STK11	T84	G88S	88	Missense	distal	4	no	21.646	22.465	EPSD	ICGC;COSMIC	16.403	Up-regulation
CAMK_CAMKL_LKB_STK11_ST	Q13153	PAK1	Q15831	STK11	T109	T113I	113	Missense	distal	4	no	32.353	32.092	PhosphoSitePlus	ICGC;COSMIC	16.403	Down-regulation
CAMK_CAMKL_LKB_STK11_ST	Q13153	PAK1	Q15831	STK11	T109	I112T	112	Missense	distal	3	no	32.353	32.828	PhosphoSitePlus	ICGC;COSMIC	16.403	Up-regulation
CAMK_CAMKL_LKB_STK11_ST	Q13153	PAK1	Q15831	STK11	T109	I112V	112	Missense	distal	3	no	32.353	28.231	PhosphoSitePlus	ICGC;COSMIC	16.403	Down-regulation
CAMK_CAMKL_LKB_STK11_ST	Q13153	PAK1	Q15831	STK11	S199	R193C	193	Missense	distal	-6	no	18.471	18.421	EPSD	ICGC;COSMIC	16.403	Down-regulation
CAMK_CAMKL_LKB_STK11_ST	Q13153	PAK1	Q15831	STK11	T229	P231T	231	Missense	proximal	2	no	16.065	16.436	EPSD	ICGC	16.403	Gain
CAMK_CAMKL_LKB_STK11_ST	Q13153	PAK1	Q15831	STK11	T236	T239I	239	Missense	distal	3	no	19.750	19.275	EPSD	ICGC;COSMIC	16.403	Down-regulation
CAMK_CAMKL_LKB_STK11_ST	Q13153	PAK1	Q15831	STK11	T236	T230A	230	Missense	distal	-6	no	19.750	19.810	EPSD	ICGC;COSMIC	16.403	Up-regulation
CAMK_CAMKL_LKB_STK11_ST	Q13153	PAK1	Q15831	STK11	T236	P231T	231	Missense	distal	-5	no	19.750	19.835	EPSD	ICGC	16.403	Up-regulation
CAMK_CAMKL_LKB_STK11_ST	Q13153	PAK1	Q15831	STK11	T236	Q242K	242	Missense	distal	6	no	19.750	20.363	EPSD	ICGC	16.403	Up-regulation
CAMK_CAMKL_LKB_STK11_ST	Q13153	PAK1	Q15831	STK11	T239	T239I	239	Missense	central	0	yes	26.121	0.000	EPSD	ICGC;COSMIC	16.403	Loss
CAMK_CAMKL_LKB_STK11_ST	Q13153	PAK1	Q15831	STK11	T239	Q242K	242	Missense	distal	3	no	26.121	27.843	EPSD	ICGC	16.403	Up-regulation
CAMK_CAMKL_LKB_STK11_ST	Q13153	PAK1	Q15831	STK11	S422	T415N	415	Missense	distal	-7	no	30.133	29.343	EPSD	ICGC;COSMIC	16.403	Down-regulation
CAMK_CAMKL_LKB_STK11_ST	Q13153	PAK1	Q15831	STK11	S422	P416L	416	Missense	distal	-6	no	30.133	30.195	EPSD	ICGC	16.403	Up-regulation
CAMK_CAMKL_LKB_STK11_ST	Q14680	MELK	Q15831	STK11	T415	P410S	410	Missense	distal	-5	no	17.982	16.500	EPSD	ICGC;COSMIC	16.403	Down-regulation
CAMK_CAMKL_LKB_STK11_ST	Q13131	PRKAA1	Q15831	STK11	T183	N189S	189	Missense	distal	6	no	58.970	58.034	PhosphoSitePlus	ICGC;COSMIC;CCLE	16.403	Down-regulation
CAMK_CAMKL_LKB_STK11_ST	Q13131	PRKAA1	Q15831	STK11	T183	T183K	183	Missense	central	0	yes	58.970	0.000	PhosphoSitePlus	ICGC	16.403	Loss
CAMK_CAMKL_LKB_STK11_ST	Q13131	PRKAA1	Q15831	STK11	T244	Q246E	246	Missense	proximal	2	no	17.262	21.597	EPSD	ICGC;COSMIC	16.403	Up-regulation
CAMK_CAMKL_LKB_STK11_ST	Q13131	PRKAA1	Q15831	STK11	T244	I241M	241	Missense	distal	-3	no	17.262	17.311	EPSD	ICGC;COSMIC	16.403	Up-regulation
CAMK_CAMKL_LKB_STK11_ST	Q13131	PRKAA1	Q15831	STK11	T244	Y243C	243	Missense	proximal	-1	no	17.262	16.985	EPSD	ICGC;COSMIC	16.403	Down-regulation
CAMK_CAMKL_LKB_STK11_ST	Q13131	PRKAA1	Q15831	STK11	T244	T244A	244	Missense	central	0	yes	17.262	0.000	EPSD	ICGC;COSMIC	16.403	Loss
CAMK_CAMKL_LKB_STK11_ST	Q13131	PRKAA1	Q15831	STK11	T297	E290D	290	Missense	distal	-7	no	16.547	17.325	EPSD	ICGC;COSMIC	16.403	Up-regulation
CAMK_CAMKL_LKB_STK11_ST	Q13131	PRKAA1	Q15831	STK11	T297	M298I	298	Missense	proximal	1	no	16.547	16.549	EPSD	ICGC;COSMIC	16.403	Up-regulation
CAMK_CAMKL_LKB_STK11_ST	Q13131	PRKAA1	Q15831	STK11	T355	L362I	362	Missense	distal	7	no	21.212	22.538	EPSD	ICGC;COSMIC	16.403	Up-regulation
CAMK_CAMKL_LKB_STK11_ST	Q13131	PRKAA1	Q15831	STK11	T355	A354V	354	Missense	proximal	-1	no	21.212	21.025	EPSD	ICGC;COSMIC	16.403	Down-regulation
CAMK_CAMKL_LKB_STK11_ST	Q13131	PRKAA1	Q15831	STK11	T355	S360F	360	Missense	distal	5	no	21.212	19.851	EPSD	ICGC	16.403	Down-regulation
CAMK_CAMKL_LKB_STK11_ST	Q13131	PRKAA1	Q15831	STK11	T355	D350Y	350	Missense	distal	-5	no	21.212	20.078	EPSD	ICGC;COSMIC	16.403	Down-regulation
CAMK_CAMKL_LKB_STK11_ST	Q13131	PRKAA1	Q15831	STK11	S496	S498C	498	Missense	proximal	2	no	38.291	42.978	EPSD	ICGC;COSMIC	16.403	Up-regulation
CAMK_CAMKL_LKB_STK11_ST	Q13131	PRKAA1	Q15831	STK11	S496	R501P	501	Missense	distal	5	no	38.291	38.741	EPSD	ICGC;COSMIC	16.403	Up-regulation
CAMK_CAMKL_LKB_STK11_ST	Q13131	PRKAA1	Q15831	STK11	S496	C503Y	503	Missense	distal	7	no	38.291	38.211	EPSD	ICGC	16.403	Down-regulation
CAMK_CAMKL_LKB_STK11_ST	Q13131	PRKAA1	Q15831	STK11	S496	Y500C	500	Missense	distal	4	no	38.291	38.686	EPSD	ICGC;COSMIC	16.403	Up-regulation
CAMK_CAMKL_LKB_STK11_ST	Q13131	PRKAA1	Q15831	STK11	T526	S530C	530	Missense	distal	4	no	23.758	24.142	EPSD	ICGC;COSMIC	16.403	Up-regulation
CAMK_CAMKL_LKB_STK11_ST	Q13131	PRKAA1	Q15831	STK11	T526	S524Y	524	Missense	proximal	-2	no	23.758	20.248	EPSD	ICGC;COSMIC	16.403	Down-regulation
CAMK_CAMKL_LKB_STK11_ST	Q96L34	MARK4	Q15831	STK11	S210	D213H	213	Missense	distal	3	no	17.604	11.971	EPSD	ICGC;COSMIC	16.403	Loss
CAMK_CAMKL_LKB_STK11_ST	Q96L34	MARK4	Q15831	STK11	S210	S203I	203	Missense	distal	-7	no	17.604	17.611	EPSD	ICGC	16.403	Up-regulation
CAMK_CAMKL_LKB_STK11_ST	Q96L34	MARK4	Q15831	STK11	S210	D213G	213	Missense	distal	3	no	17.604	17.327	EPSD	ICGC;COSMIC	16.403	Down-regulation
CAMK_CAMKL_LKB_STK11_ST	Q96L34	MARK4	Q15831	STK11	T214	D213H	213	Missense	proximal	-1	no	60.238	60.433	PhosphoSitePlus	ICGC;COSMIC	16.403	Up-regulation
CAMK_CAMKL_LKB_STK11_ST	Q96L34	MARK4	Q15831	STK11	T214	P220S	220	Missense	distal	6	no	60.238	58.718	PhosphoSitePlus	ICGC;COSMIC	16.403	Down-regulation
CAMK_CAMKL_LKB_STK11_ST	Q96L34	MARK4	Q15831	STK11	T214	D213G	213	Missense	proximal	-1	no	60.238	60.413	PhosphoSitePlus	ICGC;COSMIC	16.403	Up-regulation
CAMK_CAMKL_LKB_STK11_ST	Q96L34	MARK4	Q15831	STK11	S458	R455W	455	Missense	distal	-3	no	18.884	18.809	EPSD	ICGC;COSMIC	16.403	Down-regulation
CAMK_CAMKL_LKB_STK11_ST	Q96L34	MARK4	Q15831	STK11	S458	R451W	451	Missense	distal	-7	no	18.884	19.241	EPSD	ICGC;COSMIC	16.403	Up-regulation
CAMK_CAMKL_LKB_STK11_ST	Q96L34	MARK4	Q15831	STK11	S458	G454C	454	Missense	distal	-4	no	18.884	18.835	EPSD	ICGC	16.403	Down-regulation
CAMK_CAMKL_LKB_STK11_ST	Q96L34	MARK4	Q15831	STK11	T568	R561L	561	Missense	distal	-7	no	24.452	25.013	EPSD	ICGC;COSMIC	16.403	Up-regulation
CAMK_CAMKL_LKB_STK11_ST	Q96L34	MARK4	Q15831	STK11	T568	R561C	561	Missense	distal	-7	no	24.452	25.324	EPSD	ICGC;COSMIC	16.403	Up-regulation
CAMK_CAMKL_LKB_STK11_ST	Q96L34	MARK4	Q15831	STK11	T568	R575W	575	Missense	distal	7	no	24.452	25.040	EPSD	ICGC	16.403	Up-regulation
CAMK_CAMKL_LKB_STK11_ST	Q96L34	MARK4	Q15831	STK11	T568	T564I	564	Missense	distal	-4	no	24.452	24.178	EPSD	ICGC	16.403	Down-regulation
CAMK_CAMKL_LKB_STK11_ST	Q96L34	MARK4	Q15831	STK11	T568	R575L	575	Missense	distal	7	no	24.452	23.673	EPSD	ICGC;COSMIC	16.403	Down-regulation
CAMK_CAMKL_LKB_STK11_ST	P38936	CDKN1A	Q15831	STK11	T80	R86Q	86	Missense	distal	6	no	18.169	18.293	PhosphoSitePlus	ICGC;COSMIC	16.403	Up-regulation
CAMK_CAMKL_LKB_STK11_ST	Q9Y2K2	SIK3	Q15831	STK11	T30	V34F	34	Missense	distal	4	no	24.342	23.752	EPSD	ICGC	16.403	Down-regulation
CAMK_CAMKL_LKB_STK11_ST	Q9Y2K2	SIK3	Q15831	STK11	T30	V34A	34	Missense	distal	4	no	24.342	24.727	EPSD	ICGC	16.403	Up-regulation
CAMK_CAMKL_LKB_STK11_ST	Q9Y2K2	SIK3	Q15831	STK11	T30	I36M	36	Missense	distal	6	no	24.342	25.228	EPSD	ICGC	16.403	Up-regulation
CAMK_CAMKL_LKB_STK11_ST	Q9Y2K2	SIK3	Q15831	STK11	T30	R24L	24	Missense	distal	-6	no	24.342	24.339	EPSD	ICGC	16.403	Down-regulation
CAMK_CAMKL_LKB_STK11_ST	Q9Y2K2	SIK3	Q15831	STK11	T163	T156I	156	Missense	distal	-7	no	60.537	59.608	EPSD	ICGC	16.403	Down-regulation
CAMK_CAMKL_LKB_STK11_ST	Q9Y2K2	SIK3	Q15831	STK11	T558	R560S	560	Missense	proximal	2	no	12.456	16.851	EPSD	ICGC	16.403	Gain
CAMK_CAMKL_LKB_STK11_ST	Q8IWQ3	BRSK2	Q15831	STK11	T443	S439F	439	Missense	distal	-4	no	34.309	34.611	EPSD	ICGC;COSMIC	16.403	Up-regulation
CAMK_CAMKL_LKB_STK11_ST	Q9P0L2	MARK1	Q15831	STK11	S486	V493I	493	Missense	distal	7	no	19.278	19.591	EPSD	ICGC;COSMIC	16.403	Up-regulation
CAMK_CAMKL_LKB_STK11_ST	Q9P0L2	MARK1	Q15831	STK11	T598	R601H	601	Missense	distal	3	no	16.239	17.369	EPSD	ICGC;COSMIC	16.403	Gain
CAMK_CAMKL_LKB_STK11_ST	Q9P0L2	MARK1	Q15831	STK11	T598	R601P	601	Missense	distal	3	no	16.239	19.202	EPSD	ICGC;COSMIC	16.403	Gain
CAMK_CAMKL_LKB_STK11_ST	Q9P0L2	MARK1	Q15831	STK11	S679	S677L	677	Missense	proximal	-2	no	14.656	18.486	EPSD	ICGC	16.403	Gain
CAMK_CAMKL_LKB_STK11_ST	P04637	TP53	Q15831	STK11	S15	E11K	11	Missense	distal	-4	no	16.759	16.833	EPSD;PhosphoSitePlus	ICGC;COSMIC	16.403	Up-regulation
CAMK_CAMKL_LKB_STK11_ST	P04637	TP53	Q15831	STK11	T155	R156L	156	Missense	proximal	1	no	17.567	17.575	EPSD	ICGC;COSMIC	16.403	Up-regulation
CAMK_CAMKL_LKB_STK11_ST	P04637	TP53	Q15831	STK11	T155	P152R	152	Missense	distal	-3	no	17.567	17.621	EPSD	ICGC;COSMIC	16.403	Up-regulation
CAMK_CAMKL_LKB_STK11_ST	P04637	TP53	Q15831	STK11	T155	G154S	154	Missense	proximal	-1	no	17.567	17.651	EPSD	ICGC;COSMIC	16.403	Up-regulation
CAMK_CAMKL_LKB_STK11_ST	P04637	TP53	Q15831	STK11	T155	V157A	157	Missense	proximal	2	no	17.567	15.171	EPSD	ICGC;COSMIC	16.403	Loss
CAMK_CAMKL_LKB_STK11_ST	P04637	TP53	Q15831	STK11	T155	I162S	162	Missense	distal	7	no	17.567	17.064	EPSD	ICGC;COSMIC	16.403	Down-regulation
CAMK_CAMKL_LKB_STK11_ST	P04637	TP53	Q15831	STK11	T155	P151F	151	Missense	distal	-4	no	17.567	17.379	EPSD	ICGC;COSMIC	16.403	Down-regulation
CAMK_CAMKL_LKB_STK11_ST	P04637	TP53	Q15831	STK11	T155	M160R	160	Missense	distal	5	no	17.567	17.286	EPSD	ICGC;COSMIC	16.403	Down-regulation
CAMK_CAMKL_LKB_STK11_ST	P04637	TP53	Q15831	STK11	T387	F385L	385	Missense	proximal	-2	no	13.208	19.761	EPSD	ICGC;COSMIC	16.403	Gain
CAMK_CAMKL_LKB_STK11_ST	P46937	YAP1	Q15831	STK11	T143	V137F	137	Missense	distal	-6	no	30.334	30.361	EPSD	ICGC;COSMIC	16.403	Up-regulation
CAMK_CAMKL_LKB_STK11_ST	P46937	YAP1	Q15831	STK11	T143	T145N	145	Missense	proximal	2	no	30.334	28.952	EPSD	ICGC	16.403	Down-regulation
CAMK_CAMKL_LKB_STK11_ST	P46937	YAP1	Q15831	STK11	S163	R161L	161	Missense	proximal	-2	no	16.377	21.063	EPSD	ICGC	16.403	Gain
CAMK_CAMKL_LKB_STK11_ST	P46937	YAP1	Q15831	STK11	S350	S350N	350	Missense	central	0	yes	28.145	0.000	EPSD	ICGC;COSMIC	16.403	Loss
CAMK_CAMKL_LKB_STK11_ST	P46937	YAP1	Q15831	STK11	T398	L402P	402	Missense	distal	4	no	22.358	22.154	EPSD	ICGC;COSMIC	16.403	Down-regulation
CAMK_CAMKL_LKB_STK11_ST	P46937	YAP1	Q15831	STK11	T398	R394Q	394	Missense	distal	-4	no	22.358	22.488	EPSD	ICGC;COSMIC	16.403	Up-regulation
CAMK_CAMKL_LKB_STK11_ST	P46937	YAP1	Q15831	STK11	T398	S397I	397	Missense	proximal	-1	no	22.358	21.939	EPSD	ICGC	16.403	Down-regulation
CAMK_CAMKL_LKB_STK11_ST	P46937	YAP1	Q15831	STK11	T398	H392N	392	Missense	distal	-6	no	22.358	22.361	EPSD	ICGC;COSMIC	16.403	Up-regulation
CAMK_CAMKL_LKB_STK11_ST	P46937	YAP1	Q15831	STK11	T398	T398A	398	Missense	central	0	yes	22.358	0.000	EPSD	ICGC;COSMIC	16.403	Loss
CAMK_CAMKL_LKB_STK11_ST	P46937	YAP1	Q15831	STK11	T412	V409F	409	Missense	distal	-3	no	19.292	19.233	EPSD	ICGC	16.403	Down-regulation
CAMK_CAMKL_LKB_STK11_ST	P46937	YAP1	Q15831	STK11	T425	E422K	422	Missense	distal	-3	no	27.793	27.834	EPSD	ICGC;COSMIC	16.403	Up-regulation
CAMK_CAMKL_LKB_STK11_ST	P46937	YAP1	Q15831	STK11	T425	M423I	423	Missense	proximal	-2	no	27.793	25.656	EPSD	ICGC	16.403	Down-regulation
CAMK_CAMKL_LKB_STK11_ST	P46937	YAP1	Q15831	STK11	T425	N430T	430	Missense	distal	5	no	27.793	27.970	EPSD	ICGC;COSMIC	16.403	Up-regulation
CAMK_CAMKL_LKB_STK11_ST	Q9H0K1	SIK2	Q15831	STK11	T458	E461D	461	Missense	distal	3	no	19.538	23.824	EPSD	ICGC	16.403	Up-regulation
CAMK_CAMKL_LKB_STK11_ST	Q9H0K1	SIK2	Q15831	STK11	T458	D453Y	453	Missense	distal	-5	no	19.538	18.404	EPSD	ICGC;COSMIC	16.403	Down-regulation
CAMK_CAMKL_LKB_STK11_ST	Q9H0K1	SIK2	Q15831	STK11	T476	R481I	481	Missense	distal	5	no	20.870	20.706	EPSD	ICGC	16.403	Down-regulation
CAMK_CAMKL_LKB_STK11_ST	Q9H0K1	SIK2	Q15831	STK11	T476	R477L	477	Missense	proximal	1	no	20.870	20.878	EPSD	ICGC	16.403	Up-regulation
CAMK_CAMKL_LKB_STK11_ST	Q7KZI7	MARK2	Q15831	STK11	S212	A216S	216	Missense	distal	4	no	22.455	21.461	EPSD	ICGC	16.403	Down-regulation
CAMK_CAMKL_LKB_STK11_ST	Q7KZI7	MARK2	Q15831	STK11	S759	L755R	755	Missense	distal	-4	no	19.465	19.494	EPSD	ICGC;COSMIC	16.403	Up-regulation
CAMK_CAMKL_LKB_STK11_ST	Q9NRH2	SNRK	Q15831	STK11	T157	G152S	152	Missense	distal	-5	no	27.664	25.924	EPSD	ICGC;COSMIC	16.403	Down-regulation
CAMK_CAMKL_LKB_STK11_ST	Q9NRH2	SNRK	Q15831	STK11	T173	G176A	176	Missense	distal	3	no	41.986	34.780	PhosphoSitePlus	ICGC;COSMIC	16.403	Down-regulation
CAMK_CAMKL_LKB_STK11_ST	Q9NRH2	SNRK	Q15831	STK11	T173	S174I	174	Missense	proximal	1	no	41.986	41.993	PhosphoSitePlus	ICGC;COSMIC	16.403	Up-regulation
CAMK_CAMKL_LKB_STK11_ST	Q9NRH2	SNRK	Q15831	STK11	T247	L250P	250	Missense	distal	3	no	13.475	22.920	EPSD	ICGC;COSMIC	16.403	Gain
CAMK_CAMK2_CAMK2D_ST	P55327	TPD52	Q13557-8	CAMK2D	S115	G112V	112	Missense	distal	-3	no	12.998	43.572	EPSD	ICGC;COSMIC	37.605	Gain
CAMK_CAMK2_CAMK2D_ST	P55327	TPD52	Q13557-8	CAMK2D	S176	S176F	176	Missense	central	0	yes	76.022	0.000	PhosphoSitePlus	ICGC;COSMIC	37.605	Loss
CAMK_CAMKL_MARK_MARK1_ST	P10636	MAPT	Q9P0L2	MARK1	S228	P233H	233	Missense	distal	5	no	0.334	0.338	EPSD	ICGC;COSMIC	0.230	Up-regulation
CAMK_CAMKL_MARK_MARK1_ST	P10636	MAPT	Q9P0L2	MARK1	S228	S232F	232	Missense	distal	4	no	0.334	0.230	EPSD	ICGC	0.230	Down-regulation
CAMK_CAMKL_MARK_MARK1_ST	P10636	MAPT	Q9P0L2	MARK1	S228	D225N	225	Missense	distal	-3	no	0.334	0.329	EPSD	ICGC	0.230	Down-regulation
CAMK_CAMKL_MARK_MARK1_ST	P10636	MAPT	Q9P0L2	MARK1	S228	V224I	224	Missense	distal	-4	no	0.334	0.343	EPSD	ICGC;COSMIC	0.230	Up-regulation
CAMK_CAMKL_MARK_MARK1_ST	P10636	MAPT	Q9P0L2	MARK1	S447	Y441H	441	Missense	distal	-6	no	0.378	0.381	EPSD	ICGC;COSMIC	0.230	Up-regulation
CAMK_CAMKL_MARK_MARK1_ST	P10636	MAPT	Q9P0L2	MARK1	S527	G521R	521	Missense	distal	-6	no	0.291	0.285	EPSD	ICGC;COSMIC	0.230	Down-regulation
CAMK_CAMKL_MARK_MARK1_ST	Q155Q3	DIXDC1	Q9P0L2	MARK1	S185	S186I	186	Missense	proximal	1	no	0.221	0.230	EPSD	ICGC	0.230	Gain
CAMK_CAMKL_MARK_MARK1_ST	Q99689	FEZ1	Q9P0L2	MARK1	S247	F246L	246	Missense	proximal	-1	no	0.229	0.236	EPSD	ICGC;COSMIC	0.230	Gain
CAMK_CAMKL_MARK_MARK1_ST	Q99689	FEZ1	Q9P0L2	MARK1	S316	F315V	315	Missense	proximal	-1	no	0.301	0.294	EPSD	ICGC;COSMIC	0.230	Down-regulation
CAMK_CAMKL_MARK_MARK1_ST	Q99689	FEZ1	Q9P0L2	MARK1	S316	P311H	311	Missense	distal	-5	no	0.301	0.303	EPSD	ICGC	0.230	Up-regulation
AGC_GRK_GRK_GRK7_ST	Q16625	OCLN	Q8WTQ7	GRK7	S3	L6F	6	Missense	distal	3	no	1.539	1.478	EPSD	ICGC	1.098	Down-regulation
Other_ULK_ULK_ULK3_ST	Q6PHR2	ULK3	Q6PHR2	ULK3	S350	L355P	355	Missense	distal	5	no	4.739	4.914	EPSD;PhosphoSitePlus	ICGC;COSMIC	1.534	Up-regulation
CAMK_CAMKL_MARK_MARK2_ST	Q8WUI4	HDAC7	Q7KZI7	MARK2	T104	H106N	106	Missense	proximal	2	no	266.611	290.507	EPSD	ICGC	271.430	Gain
CAMK_CAMKL_MARK_MARK2_ST	Q8WUI4	HDAC7	Q7KZI7	MARK2	T104	P110L	110	Missense	distal	6	no	266.611	281.144	EPSD	ICGC;COSMIC	271.430	Gain
CAMK_CAMKL_MARK_MARK2_ST	Q8WUI4	HDAC7	Q7KZI7	MARK2	T104	A100T	100	Missense	distal	-4	no	266.611	279.497	EPSD	ICGC;COSMIC	271.430	Gain
CAMK_CAMKL_MARK_MARK2_ST	Q8WUI4	HDAC7	Q7KZI7	MARK2	S109	P113L	113	Missense	distal	4	no	159.756	288.335	EPSD	ICGC;COSMIC	271.430	Gain
CAMK_CAMKL_MARK_MARK2_ST	Q8WUI4	HDAC7	Q7KZI7	MARK2	S155	R151H	151	Missense	distal	-4	no	371.176	357.261	PhosphoSitePlus	ICGC;COSMIC;CCLE	271.430	Down-regulation
CAMK_CAMKL_MARK_MARK2_ST	Q8WUI4	HDAC7	Q7KZI7	MARK2	S155	R162P	162	Missense	distal	7	no	371.176	366.402	PhosphoSitePlus	ICGC;COSMIC	271.430	Down-regulation
CAMK_CAMKL_MARK_MARK2_ST	Q8WUI4	HDAC7	Q7KZI7	MARK2	S155	S155F	155	Missense	central	0	yes	371.176	0.000	PhosphoSitePlus	ICGC;COSMIC	271.430	Loss
CAMK_CAMKL_MARK_MARK2_ST	Q8WUI4	HDAC7	Q7KZI7	MARK2	S181	P183T	183	Missense	proximal	2	no	286.861	271.217	EPSD	ICGC	271.430	Loss
CAMK_CAMKL_MARK_MARK2_ST	Q8WUI4	HDAC7	Q7KZI7	MARK2	S181	K179R	179	Missense	proximal	-2	no	286.861	288.288	EPSD	ICGC;COSMIC	271.430	Up-regulation
CAMK_CAMKL_MARK_MARK2_ST	Q8WUI4	HDAC7	Q7KZI7	MARK2	S181	A182V	182	Missense	proximal	1	no	286.861	297.327	EPSD	ICGC;COSMIC	271.430	Up-regulation
CAMK_CAMKL_MARK_MARK2_ST	P56524	HDAC4	Q7KZI7	MARK2	S5	P7Q	7	Missense	proximal	2	no	306.977	284.277	EPSD	ICGC;COSMIC	271.430	Down-regulation
CAMK_CAMKL_MARK_MARK2_ST	P56524	HDAC4	Q7KZI7	MARK2	S5	S5R	5	Missense	central	0	yes	306.977	0.000	EPSD	ICGC	271.430	Loss
CAMK_CAMKL_MARK_MARK2_ST	P56524	HDAC4	Q7KZI7	MARK2	S339	R332Q	332	Missense	distal	-7	no	319.764	319.851	EPSD	ICGC	271.430	Up-regulation
CAMK_CAMKL_MARK_MARK2_ST	Q8TEW0	PARD3	Q7KZI7	MARK2	S144	P137H	137	Missense	distal	-7	no	396.547	396.573	EPSD;PhosphoSitePlus	ICGC;COSMIC	271.430	Up-regulation
CAMK_CAMKL_MARK_MARK2_ST	Q8TEW0	PARD3	Q7KZI7	MARK2	S201	L202V	202	Missense	proximal	1	no	277.002	286.091	EPSD	ICGC	271.430	Up-regulation
CAMK_CAMKL_MARK_MARK2_ST	Q8TEW0	PARD3	Q7KZI7	MARK2	S201	T206A	206	Missense	distal	5	no	277.002	264.892	EPSD	ICGC;COSMIC	271.430	Loss
CAMK_CAMKL_MARK_MARK2_ST	Q8TEW0	PARD3	Q7KZI7	MARK2	S207	L202V	202	Missense	distal	-5	no	268.010	274.914	EPSD	ICGC	271.430	Gain
CAMK_CAMKL_MARK_MARK2_ST	Q8TEW0	PARD3	Q7KZI7	MARK2	S207	T206A	206	Missense	proximal	-1	no	268.010	273.014	EPSD	ICGC;COSMIC	271.430	Gain
CAMK_CAMKL_MARK_MARK2_ST	Q8TEW0	PARD3	Q7KZI7	MARK2	S207	Q212K	212	Missense	distal	5	no	268.010	280.917	EPSD	ICGC	271.430	Gain
CAMK_CAMKL_MARK_MARK2_ST	Q8TEW0	PARD3	Q7KZI7	MARK2	T298	G296S	296	Missense	proximal	-2	no	317.235	319.758	EPSD	ICGC;COSMIC	271.430	Up-regulation
CAMK_CAMKL_MARK_MARK2_ST	Q8TEW0	PARD3	Q7KZI7	MARK2	T298	L299M	299	Missense	proximal	1	no	317.235	316.498	EPSD	ICGC;COSMIC	271.430	Down-regulation
CAMK_CAMKL_MARK_MARK2_ST	Q8TEW0	PARD3	Q7KZI7	MARK2	S396	A397T	397	Missense	proximal	1	no	301.893	300.110	EPSD	ICGC;COSMIC	271.430	Down-regulation
CAMK_CAMKL_MARK_MARK2_ST	Q8TEW0	PARD3	Q7KZI7	MARK2	T446	T446N	446	Missense	central	0	yes	295.550	0.000	EPSD	ICGC	271.430	Loss
CAMK_CAMKL_MARK_MARK2_ST	Q8TEW0	PARD3	Q7KZI7	MARK2	T446	T453N	453	Missense	distal	7	no	295.550	303.245	EPSD	ICGC;COSMIC	271.430	Up-regulation
CAMK_CAMKL_MARK_MARK2_ST	Q8TEW0	PARD3	Q7KZI7	MARK2	T453	T446N	446	Missense	distal	-7	no	281.736	281.699	EPSD	ICGC	271.430	Down-regulation
CAMK_CAMKL_MARK_MARK2_ST	Q8TEW0	PARD3	Q7KZI7	MARK2	T453	T453N	453	Missense	central	0	yes	281.736	0.000	EPSD	ICGC;COSMIC	271.430	Loss
CAMK_CAMKL_MARK_MARK2_ST	Q8TEW0	PARD3	Q7KZI7	MARK2	T468	K465E	465	Missense	distal	-3	no	273.513	160.988	EPSD	ICGC;COSMIC	271.430	Loss
CAMK_CAMKL_MARK_MARK2_ST	Q8TEW0	PARD3	Q7KZI7	MARK2	T468	N461K	461	Missense	distal	-7	no	273.513	273.542	EPSD	ICGC;COSMIC	271.430	Up-regulation
CAMK_CAMKL_MARK_MARK2_ST	Q8TEW0	PARD3	Q7KZI7	MARK2	T468	L464H	464	Missense	distal	-4	no	273.513	265.994	EPSD	ICGC;COSMIC	271.430	Loss
CAMK_CAMKL_MARK_MARK2_ST	Q8TEW0	PARD3	Q7KZI7	MARK2	T468	E469K	469	Missense	proximal	1	no	273.513	268.520	EPSD	ICGC	271.430	Loss
CAMK_CAMKL_MARK_MARK2_ST	Q8TEW0	PARD3	Q7KZI7	MARK2	S596	E590D	590	Missense	distal	-6	no	364.172	365.378	EPSD	ICGC;COSMIC	271.430	Up-regulation
CAMK_CAMKL_MARK_MARK2_ST	Q8TEW0	PARD3	Q7KZI7	MARK2	S596	S598Y	598	Missense	proximal	2	no	364.172	346.757	EPSD	ICGC	271.430	Down-regulation
CAMK_CAMKL_MARK_MARK2_ST	Q8TEW0	PARD3	Q7KZI7	MARK2	S598	S598Y	598	Missense	central	0	yes	286.486	0.000	EPSD	ICGC	271.430	Loss
CAMK_CAMKL_MARK_MARK2_ST	Q8TEW0	PARD3	Q7KZI7	MARK2	S598	S604N	604	Missense	distal	6	no	286.486	293.208	EPSD	ICGC;COSMIC	271.430	Up-regulation
CAMK_CAMKL_MARK_MARK2_ST	Q8TEW0	PARD3	Q7KZI7	MARK2	S604	S598Y	598	Missense	distal	-6	no	274.692	273.947	EPSD	ICGC	271.430	Down-regulation
CAMK_CAMKL_MARK_MARK2_ST	Q8TEW0	PARD3	Q7KZI7	MARK2	S604	S604N	604	Missense	central	0	yes	274.692	0.000	EPSD	ICGC;COSMIC	271.430	Loss
CAMK_CAMKL_MARK_MARK2_ST	Q8TEW0	PARD3	Q7KZI7	MARK2	S667	T661S	661	Missense	distal	-6	no	337.841	337.575	EPSD	ICGC;COSMIC	271.430	Down-regulation
CAMK_CAMKL_MARK_MARK2_ST	Q8TEW0	PARD3	Q7KZI7	MARK2	S715	I714N	714	Missense	proximal	-1	no	266.133	276.583	EPSD	ICGC;COSMIC	271.430	Gain
CAMK_CAMKL_MARK_MARK2_ST	Q8TEW0	PARD3	Q7KZI7	MARK2	S717	I714N	714	Missense	distal	-3	no	204.094	286.104	EPSD	ICGC;COSMIC	271.430	Gain
CAMK_CAMKL_MARK_MARK2_ST	Q8TEW0	PARD3	Q7KZI7	MARK2	S728	G721W	721	Missense	distal	-7	no	310.369	310.427	EPSD	ICGC;COSMIC	271.430	Up-regulation
CAMK_CAMKL_MARK_MARK2_ST	Q8TEW0	PARD3	Q7KZI7	MARK2	S728	G721V	721	Missense	distal	-7	no	310.369	310.305	EPSD	ICGC;COSMIC	271.430	Down-regulation
CAMK_CAMKL_MARK_MARK2_ST	Q8TEW0	PARD3	Q7KZI7	MARK2	S748	G743C	743	Missense	distal	-5	no	307.606	298.761	EPSD	ICGC;COSMIC	271.430	Down-regulation
CAMK_CAMKL_MARK_MARK2_ST	Q8TEW0	PARD3	Q7KZI7	MARK2	S852	K846T	846	Missense	distal	-6	no	338.054	337.249	EPSD	ICGC;COSMIC	271.430	Down-regulation
CAMK_CAMKL_MARK_MARK2_ST	Q8TEW0	PARD3	Q7KZI7	MARK2	S873	P880L	880	Missense	distal	7	no	341.821	345.455	PhosphoSitePlus;EPSD	ICGC;COSMIC	271.430	Up-regulation
CAMK_CAMKL_MARK_MARK2_ST	Q8TEW0	PARD3	Q7KZI7	MARK2	S873	P874S	874	Missense	proximal	1	no	341.821	344.103	PhosphoSitePlus;EPSD	ICGC;COSMIC;GDSC	271.430	Up-regulation
CAMK_CAMKL_MARK_MARK2_ST	Q8TEW0	PARD3	Q7KZI7	MARK2	S875	P880L	880	Missense	distal	5	no	281.356	295.396	EPSD	ICGC;COSMIC	271.430	Up-regulation
CAMK_CAMKL_MARK_MARK2_ST	Q8TEW0	PARD3	Q7KZI7	MARK2	S875	P874S	874	Missense	proximal	-1	no	281.356	292.557	EPSD	ICGC;COSMIC;GDSC	271.430	Up-regulation
CAMK_CAMKL_MARK_MARK2_ST	Q8TEW0	PARD3	Q7KZI7	MARK2	S881	P880L	880	Missense	proximal	-1	no	271.305	291.072	EPSD	ICGC;COSMIC	271.430	Gain
CAMK_CAMKL_MARK_MARK2_ST	Q8TEW0	PARD3	Q7KZI7	MARK2	S887	P880L	880	Missense	distal	-7	no	300.286	300.269	EPSD	ICGC;COSMIC	271.430	Down-regulation
CAMK_CAMKL_MARK_MARK2_ST	Q8TEW0	PARD3	Q7KZI7	MARK2	S1107	P1114L	1114	Missense	distal	7	no	293.283	296.917	EPSD	ICGC;COSMIC	271.430	Up-regulation
CAMK_CAMKL_MARK_MARK2_ST	Q8TEW0	PARD3	Q7KZI7	MARK2	S1116	P1114L	1114	Missense	proximal	-2	no	320.292	323.104	EPSD	ICGC;COSMIC	271.430	Up-regulation
CAMK_CAMKL_MARK_MARK2_ST	Q8TEW0	PARD3	Q7KZI7	MARK2	S1337	P1333T	1333	Missense	distal	-4	no	283.746	272.468	EPSD	ICGC;COSMIC	271.430	Down-regulation
CAMK_CAMKL_MARK_MARK2_ST	Q8TEW0	PARD3	Q7KZI7	MARK2	S1337	L1342I	1342	Missense	distal	5	no	283.746	275.425	EPSD	ICGC	271.430	Down-regulation
CAMK_CAMKL_MARK_MARK2_ST	Q8TEW0	PARD3	Q7KZI7	MARK2	T1347	L1342I	1342	Missense	distal	-5	no	286.323	286.439	EPSD	ICGC	271.430	Up-regulation
CAMK_CAMKL_MARK_MARK2_ST	Q7KZI7	MARK2	Q7KZI7	MARK2	S30	S32F	32	Missense	proximal	2	no	286.074	253.900	EPSD	ICGC;COSMIC	271.430	Loss
CAMK_CAMKL_MARK_MARK2_ST	Q7KZI7	MARK2	Q7KZI7	MARK2	S30	R36Q	36	Missense	distal	6	no	286.074	273.700	EPSD	ICGC	271.430	Down-regulation
CAMK_CAMKL_MARK_MARK2_ST	Q7KZI7	MARK2	Q7KZI7	MARK2	T58	G62C	62	Missense	distal	4	no	331.237	256.876	EPSD	ICGC;COSMIC	271.430	Loss
CAMK_CAMKL_MARK_MARK2_ST	Q7KZI7	MARK2	Q7KZI7	MARK2	T58	G60C	60	Missense	proximal	2	no	331.237	349.013	EPSD	ICGC;COSMIC	271.430	Up-regulation
CAMK_CAMKL_MARK_MARK2_ST	Q7KZI7	MARK2	Q7KZI7	MARK2	S365	L359M	359	Missense	distal	-6	no	277.431	275.351	EPSD	ICGC;COSMIC	271.430	Down-regulation
CAMK_CAMKL_MARK_MARK2_ST	Q7KZI7	MARK2	Q7KZI7	MARK2	S398	R397H	397	Missense	proximal	-1	no	272.534	277.657	EPSD	ICGC;COSMIC	271.430	Up-regulation
CAMK_CAMKL_MARK_MARK2_ST	Q7KZI7	MARK2	Q7KZI7	MARK2	S400	R397H	397	Missense	distal	-3	no	345.504	322.524	PhosphoSitePlus	ICGC;COSMIC	271.430	Down-regulation
CAMK_CAMKL_MARK_MARK2_ST	Q7KZI7	MARK2	Q7KZI7	MARK2	S449	P454S	454	Missense	distal	5	no	303.866	310.395	EPSD	ICGC;COSMIC	271.430	Up-regulation
CAMK_CAMKL_MARK_MARK2_ST	Q7KZI7	MARK2	Q7KZI7	MARK2	S648	R653L	653	Missense	distal	5	no	312.222	318.005	EPSD	ICGC;COSMIC	271.430	Up-regulation
CAMK_CAMKL_MARK_MARK2_ST	Q7KZI7	MARK2	Q7KZI7	MARK2	S648	R653W	653	Missense	distal	5	no	312.222	286.602	EPSD	ICGC;COSMIC	271.430	Down-regulation
CAMK_CAMKL_MARK_MARK2_ST	Q92974	ARHGEF2	Q7KZI7	MARK2	S142	R139S	139	Missense	distal	-3	no	302.986	234.465	EPSD	ICGC	271.430	Loss
CAMK_CAMKL_MARK_MARK2_ST	Q92974	ARHGEF2	Q7KZI7	MARK2	S143	R139S	139	Missense	distal	-4	no	344.445	344.844	EPSD;PhosphoSitePlus	ICGC	271.430	Up-regulation
CAMK_CAMKL_MARK_MARK2_ST	Q92974	ARHGEF2	Q7KZI7	MARK2	S163	R169L	169	Missense	distal	6	no	307.534	315.573	EPSD	ICGC;COSMIC	271.430	Up-regulation
CAMK_CAMKL_MARK_MARK2_ST	Q92974	ARHGEF2	Q7KZI7	MARK2	S172	R169L	169	Missense	distal	-3	no	393.740	359.833	EPSD;PhosphoSitePlus	ICGC;COSMIC	271.430	Down-regulation
CAMK_CAMKL_MARK_MARK2_ST	Q92974	ARHGEF2	Q7KZI7	MARK2	S174	R169L	169	Missense	distal	-5	no	296.599	298.442	EPSD	ICGC;COSMIC	271.430	Up-regulation
CAMK_CAMKL_MARK_MARK2_ST	Q92974	ARHGEF2	Q7KZI7	MARK2	T175	R169L	169	Missense	distal	-6	no	275.823	277.441	EPSD	ICGC;COSMIC	271.430	Up-regulation
CAMK_CAMKL_MARK_MARK2_ST	Q92974	ARHGEF2	Q7KZI7	MARK2	S719	S722C	722	Missense	distal	3	no	272.879	301.077	EPSD	ICGC	271.430	Up-regulation
CAMK_CAMKL_MARK_MARK2_ST	Q92974	ARHGEF2	Q7KZI7	MARK2	S940	E935K	935	Missense	distal	-5	no	324.866	331.023	EPSD	ICGC	271.430	Up-regulation
CAMK_CAMKL_MARK_MARK2_ST	P10636	MAPT	Q7KZI7	MARK2	T17	A15T	15	Missense	proximal	-2	no	321.150	321.701	EPSD	ICGC;COSMIC	271.430	Up-regulation
CAMK_CAMKL_MARK_MARK2_ST	P10636	MAPT	Q7KZI7	MARK2	T17	M11I	11	Missense	distal	-6	no	321.150	322.156	EPSD	ICGC	271.430	Up-regulation
CAMK_CAMKL_MARK_MARK2_ST	P10636	MAPT	Q7KZI7	MARK2	S214	G208C	208	Missense	distal	-6	no	313.338	314.014	EPSD	ICGC;COSMIC	271.430	Up-regulation
CAMK_CAMKL_MARK_MARK2_ST	P10636	MAPT	Q7KZI7	MARK2	S214	R211S	211	Missense	distal	-3	no	313.338	244.817	EPSD	ICGC;COSMIC	271.430	Loss
CAMK_CAMKL_MARK_MARK2_ST	P10636	MAPT	Q7KZI7	MARK2	S214	G213E	213	Missense	proximal	-1	no	313.338	302.692	EPSD	ICGC;COSMIC	271.430	Down-regulation
CAMK_CAMKL_MARK_MARK2_ST	Q9NQT8	KIF13B	Q7KZI7	MARK2	T209	M215I	215	Missense	distal	6	no	283.117	283.916	EPSD	ICGC;COSMIC	271.430	Up-regulation
CAMK_CAMKL_MARK_MARK2_ST	Q9NQT8	KIF13B	Q7KZI7	MARK2	T209	R208C	208	Missense	proximal	-1	no	283.117	290.468	EPSD	ICGC;COSMIC	271.430	Up-regulation
CAMK_CAMKL_MARK_MARK2_ST	Q9NQT8	KIF13B	Q7KZI7	MARK2	S250	G256D	256	Missense	distal	6	no	336.295	330.269	EPSD	ICGC;COSMIC	271.430	Down-regulation
CAMK_CAMKL_MARK_MARK2_ST	Q9NQT8	KIF13B	Q7KZI7	MARK2	T340	T343N	343	Missense	distal	3	no	239.733	278.548	EPSD	ICGC;COSMIC	271.430	Gain
CAMK_CAMKL_MARK_MARK2_ST	Q9NQT8	KIF13B	Q7KZI7	MARK2	T513	Q508E	508	Missense	distal	-5	no	294.785	305.437	EPSD	ICGC;COSMIC	271.430	Up-regulation
CAMK_CAMKL_MARK_MARK2_ST	Q9NQT8	KIF13B	Q7KZI7	MARK2	S1398	G1402C	1402	Missense	distal	4	no	302.139	227.778	EPSD	ICGC;COSMIC	271.430	Loss
CAMK_CAMKL_MARK_MARK2_ST	Q9NQT8	KIF13B	Q7KZI7	MARK2	S1410	R1407W	1407	Missense	distal	-3	no	349.208	201.667	PhosphoSitePlus;EPSD	ICGC	271.430	Loss
CAMK_CAMKL_MARK_MARK2_ST	Q9NQT8	KIF13B	Q7KZI7	MARK2	S1432	P1433L	1433	Missense	proximal	1	no	293.304	300.075	EPSD	ICGC;CCLE	271.430	Up-regulation
CAMK_CAMKL_MARK_MARK2_ST	Q9NQT8	KIF13B	Q7KZI7	MARK2	S1438	P1433L	1433	Missense	distal	-5	no	333.142	343.078	EPSD	ICGC;CCLE	271.430	Up-regulation
CAMK_CAMKL_MARK_MARK2_ST	Q9NQT8	KIF13B	Q7KZI7	MARK2	S1449	P1453H	1453	Missense	distal	4	no	231.984	343.135	EPSD	ICGC	271.430	Gain
CAMK_CAMKL_MARK_MARK2_ST	Q9NQT8	KIF13B	Q7KZI7	MARK2	S1481	S1481P	1481	Missense	central	0	yes	298.714	0.000	EPSD	ICGC	271.430	Loss
CAMK_CAMKL_MARK_MARK2_ST	Q9NQT8	KIF13B	Q7KZI7	MARK2	S1481	V1488M	1488	Missense	distal	7	no	298.714	284.755	EPSD	ICGC	271.430	Down-regulation
CAMK_CAMKL_MARK_MARK2_ST	Q9NQT8	KIF13B	Q7KZI7	MARK2	S1481	A1484T	1484	Missense	distal	3	no	298.714	288.893	EPSD	ICGC;COSMIC	271.430	Down-regulation
CAMK_CAMKL_MARK_MARK2_ST	Q9NQT8	KIF13B	Q7KZI7	MARK2	S1481	Q1486K	1486	Missense	distal	5	no	298.714	311.620	EPSD	ICGC	271.430	Up-regulation
CAMK_CAMKL_MARK_MARK2_ST	Q9NQT8	KIF13B	Q7KZI7	MARK2	S1537	V1544A	1544	Missense	distal	7	no	293.061	275.166	EPSD	ICGC;COSMIC	271.430	Down-regulation
CAMK_CAMKL_MARK_MARK2_ST	Q9NQT8	KIF13B	Q7KZI7	MARK2	S1537	S1537Y	1537	Missense	central	0	yes	293.061	0.000	EPSD	ICGC;COSMIC	271.430	Loss
CAMK_CAMKL_MARK_MARK2_ST	Q9NQT8	KIF13B	Q7KZI7	MARK2	T1779	R1775Q	1775	Missense	distal	-4	no	276.596	266.675	EPSD	ICGC;COSMIC	271.430	Loss
CAMK_CAMKL_MARK_MARK2_ST	Q9NQT8	KIF13B	Q7KZI7	MARK2	T1779	L1781I	1781	Missense	proximal	2	no	276.596	269.531	EPSD	ICGC	271.430	Loss
CAMK_CAMKL_MARK_MARK2_ST	Q9NQT8	KIF13B	Q7KZI7	MARK2	T1779	A1785S	1785	Missense	distal	6	no	276.596	281.118	EPSD	ICGC	271.430	Up-regulation
CAMK_CAMKL_MARK_MARK2_ST	Q9NQT8	KIF13B	Q7KZI7	MARK2	S1797	A1798T	1798	Missense	proximal	1	no	315.929	314.146	EPSD	ICGC;CCLE	271.430	Down-regulation
CAMK_CAMKL_MARK_MARK2_ST	Q9NQT8	KIF13B	Q7KZI7	MARK2	S1797	L1801M	1801	Missense	distal	4	no	315.929	255.479	EPSD	ICGC;COSMIC	271.430	Loss
CAMK_CAMKL_MARK_MARK2_ST	Q9NQT8	KIF13B	Q7KZI7	MARK2	S1797	T1793I	1793	Missense	distal	-4	no	315.929	304.586	EPSD	ICGC	271.430	Down-regulation
CAMK_CAMKL_MARK_MARK2_ST	Q7L804	RAB11FIP2	Q7KZI7	MARK2	S150	N145K	145	Missense	distal	-5	no	287.118	280.678	EPSD	ICGC	271.430	Down-regulation
CAMK_CAMKL_MARK_MARK2_ST	Q7L804	RAB11FIP2	Q7KZI7	MARK2	S162	T160N	160	Missense	proximal	-2	no	292.247	294.831	EPSD	ICGC	271.430	Up-regulation
CAMK_CAMKL_MARK_MARK2_ST	Q7L804	RAB11FIP2	Q7KZI7	MARK2	S227	S234F	234	Missense	distal	7	no	390.699	392.812	PhosphoSitePlus	ICGC;COSMIC	271.430	Up-regulation
CAMK_CAMKL_MARK_MARK2_ST	Q7L804	RAB11FIP2	Q7KZI7	MARK2	S238	E239D	239	Missense	proximal	1	no	280.824	281.330	EPSD	ICGC	271.430	Up-regulation
CAMK_CAMKL_MARK_MARK2_ST	Q7L804	RAB11FIP2	Q7KZI7	MARK2	S238	S234F	234	Missense	distal	-4	no	280.824	275.244	EPSD	ICGC;COSMIC	271.430	Down-regulation
CAMK_CAMKL_MARK_MARK2_ST	Q7L804	RAB11FIP2	Q7KZI7	MARK2	T245	E239D	239	Missense	distal	-6	no	281.416	282.622	EPSD	ICGC	271.430	Up-regulation
CAMK_CAMKL_MARK_MARK2_ST	Q7L804	RAB11FIP2	Q7KZI7	MARK2	T317	P324Q	324	Missense	distal	7	no	284.180	271.705	EPSD	ICGC	271.430	Down-regulation
CAMK_CAMKL_MARK_MARK2_ST	Q7L804	RAB11FIP2	Q7KZI7	MARK2	T317	P324S	324	Missense	distal	7	no	284.180	278.248	EPSD	ICGC	271.430	Down-regulation
CAMK_CAMKL_MARK_MARK2_ST	Q7L804	RAB11FIP2	Q7KZI7	MARK2	S380	N376S	376	Missense	distal	-4	no	300.125	296.848	EPSD	ICGC;COSMIC	271.430	Down-regulation
CAMK_CAMKL_MARK_MARK2_ST	Q7L804	RAB11FIP2	Q7KZI7	MARK2	S382	N376S	376	Missense	distal	-6	no	340.659	339.231	EPSD	ICGC;COSMIC	271.430	Down-regulation
CAMK_CAMKL_MARK_MARK2_ST	Q7L804	RAB11FIP2	Q7KZI7	MARK2	S429	R434K	434	Missense	distal	5	no	289.765	293.272	EPSD	ICGC;COSMIC	271.430	Up-regulation
CAMK_CAMKL_MARK_MARK2_ST	Q99689	FEZ1	Q7KZI7	MARK2	S298	S301N	301	Missense	distal	3	no	280.634	310.536	EPSD	ICGC;COSMIC	271.430	Up-regulation
CAMK_CAMKL_MARK_MARK2_ST	Q99689	FEZ1	Q7KZI7	MARK2	S298	R292Q	292	Missense	distal	-6	no	280.634	280.083	EPSD	ICGC;COSMIC	271.430	Down-regulation
CAMK_CAMKL_MARK_MARK2_ST	Q99689	FEZ1	Q7KZI7	MARK2	S298	G296E	296	Missense	proximal	-2	no	280.634	281.219	EPSD	ICGC;COSMIC	271.430	Up-regulation
CAMK_CAMKL_MARK_MARK2_ST	Q99689	FEZ1	Q7KZI7	MARK2	S298	S298I	298	Missense	central	0	yes	280.634	0.000	EPSD	ICGC;COSMIC	271.430	Loss
CAMK_CAMKL_MARK_MARK2_ST	Q99689	FEZ1	Q7KZI7	MARK2	S298	R292W	292	Missense	distal	-6	no	280.634	278.282	EPSD	ICGC;COSMIC	271.430	Down-regulation
CAMK_CAMKL_MARK_MARK2_ST	Q99689	FEZ1	Q7KZI7	MARK2	S316	F315V	315	Missense	proximal	-1	no	292.063	276.944	EPSD	ICGC;COSMIC	271.430	Down-regulation
CAMK_CAMKL_MARK_MARK2_ST	Q99689	FEZ1	Q7KZI7	MARK2	S316	P311H	311	Missense	distal	-5	no	292.063	299.394	EPSD	ICGC	271.430	Up-regulation
CAMK_CAMKL_MARK_MARK2_ST	Q9H4P4	RNF41	Q7KZI7	MARK2	S254	A260D	260	Missense	distal	6	no	357.404	363.831	PhosphoSitePlus	ICGC	271.430	Up-regulation
CAMK_CAMKL_MARK_MARK2_ST	P78352	DLG4	Q7KZI7	MARK2	S561	V563A	563	Missense	proximal	2	no	344.237	323.082	PhosphoSitePlus	ICGC	271.430	Down-regulation
CAMK_CAMKL_MARK_MARK2_ST	Q9UQB8	BAIAP2	Q7KZI7	MARK2	S4	R5S	5	Missense	proximal	1	no	301.374	299.330	EPSD	ICGC;COSMIC	271.430	Down-regulation
CAMK_CAMKL_MARK_MARK2_ST	Q9UQB8	BAIAP2	Q7KZI7	MARK2	S6	R5S	5	Missense	proximal	-1	no	318.611	320.105	EPSD	ICGC;COSMIC	271.430	Up-regulation
CAMK_CAMKL_MARK_MARK2_ST	Q9UQB8	BAIAP2	Q7KZI7	MARK2	S446	G450W	450	Missense	distal	4	no	285.033	154.616	EPSD	ICGC;COSMIC	271.430	Loss
CAMK_CAMKL_MARK_MARK2_ST	Q9UQB8	BAIAP2	Q7KZI7	MARK2	S454	T455M	455	Missense	proximal	1	no	365.819	368.242	EPSD	ICGC;COSMIC	271.430	Up-regulation
CAMK_CAMKL_MARK_MARK2_ST	Q9UQB8	BAIAP2	Q7KZI7	MARK2	S454	G450W	450	Missense	distal	-4	no	365.819	340.223	EPSD	ICGC;COSMIC	271.430	Down-regulation
CAMK_CAMKL_MARK_MARK2_ST	Q9UQB8	BAIAP2	Q7KZI7	MARK2	S492	P496F	496	Missense	distal	4	no	174.783	271.851	EPSD	ICGC	271.430	Gain
CAMK_CAMKL_MARK_MARK2_ST	Q9UQB8	BAIAP2	Q7KZI7	MARK2	S509	A507V	507	Missense	proximal	-2	no	315.421	316.076	EPSD	ICGC;COSMIC	271.430	Up-regulation
CAMK_CAMKL_MARK_MARK2_ST	Q9UQB8	BAIAP2	Q7KZI7	MARK2	S509	A516S	516	Missense	distal	7	no	315.421	317.449	EPSD	ICGC	271.430	Up-regulation
CAMK_CAMKL_MARK_MARK2_ST	Q9UQB8	BAIAP2	Q7KZI7	MARK2	T523	D527N	527	Missense	distal	4	no	256.919	281.418	EPSD	ICGC;COSMIC	271.430	Gain
CAMK_CAMKL_MARK_MARK2_ST	Q9BXM7	PINK1	Q7KZI7	MARK2	T313	K319N	319	Missense	distal	6	no	355.598	359.903	PhosphoSitePlus	ICGC;COSMIC	271.430	Up-regulation
CAMK_CAMKL_MARK_MARK2_ST	P46939	UTRN	Q7KZI7	MARK2	S10	P11H	11	Missense	proximal	1	no	390.586	392.775	EPSD	ICGC;COSMIC	271.430	Up-regulation
CAMK_CAMKL_MARK_MARK2_ST	P46939	UTRN	Q7KZI7	MARK2	S10	S10R	10	Missense	central	0	yes	390.586	0.000	EPSD	ICGC;COSMIC	271.430	Loss
CAMK_CAMKL_MARK_MARK2_ST	P46939	UTRN	Q7KZI7	MARK2	S10	G5V	5	Missense	distal	-5	no	390.586	397.470	EPSD	ICGC;COSMIC	271.430	Up-regulation
CAMK_CAMKL_MARK_MARK2_ST	P46939	UTRN	Q7KZI7	MARK2	S10	D12G	12	Missense	proximal	2	no	390.586	369.878	EPSD	ICGC;COSMIC	271.430	Down-regulation
CAMK_CAMKL_MARK_MARK2_ST	P46939	UTRN	Q7KZI7	MARK2	S569	R572H	572	Missense	distal	3	no	280.902	258.281	EPSD	ICGC;COSMIC	271.430	Loss
CAMK_CAMKL_MARK_MARK2_ST	P46939	UTRN	Q7KZI7	MARK2	S569	E565K	565	Missense	distal	-4	no	280.902	281.168	EPSD	ICGC;COSMIC	271.430	Up-regulation
CAMK_CAMKL_MARK_MARK2_ST	P46939	UTRN	Q7KZI7	MARK2	S784	W780R	780	Missense	distal	-4	no	255.673	283.111	EPSD	ICGC;COSMIC	271.430	Gain
CAMK_CAMKL_MARK_MARK2_ST	P46939	UTRN	Q7KZI7	MARK2	S1005	K1006T	1006	Missense	proximal	1	no	310.427	314.467	EPSD	ICGC	271.430	Up-regulation
CAMK_CAMKL_MARK_MARK2_ST	P46939	UTRN	Q7KZI7	MARK2	S1005	V1002F	1002	Missense	distal	-3	no	310.427	304.196	EPSD	ICGC	271.430	Down-regulation
CAMK_CAMKL_MARK_MARK2_ST	P46939	UTRN	Q7KZI7	MARK2	S1258	E1254G	1254	Missense	distal	-4	no	361.317	362.108	PhosphoSitePlus	ICGC	271.430	Up-regulation
CAMK_CAMKL_MARK_MARK2_ST	P46939	UTRN	Q7KZI7	MARK2	T1361	T1361I	1361	Missense	central	0	yes	303.654	0.000	EPSD	ICGC;COSMIC	271.430	Loss
CAMK_CAMKL_MARK_MARK2_ST	P46939	UTRN	Q7KZI7	MARK2	T1361	K1358I	1358	Missense	distal	-3	no	303.654	189.728	EPSD	ICGC	271.430	Loss
CAMK_CAMKL_MARK_MARK2_ST	P46939	UTRN	Q7KZI7	MARK2	T1361	R1367M	1367	Missense	distal	6	no	303.654	295.694	EPSD	ICGC;COSMIC	271.430	Down-regulation
CAMK_CAMKL_MARK_MARK2_ST	P46939	UTRN	Q7KZI7	MARK2	T1361	L1364M	1364	Missense	distal	3	no	303.654	284.276	EPSD	ICGC;COSMIC	271.430	Down-regulation
CAMK_CAMKL_MARK_MARK2_ST	P46939	UTRN	Q7KZI7	MARK2	T1361	G1354V	1354	Missense	distal	-7	no	303.654	303.591	EPSD	ICGC;COSMIC	271.430	Down-regulation
CAMK_CAMKL_MARK_MARK2_ST	P46939	UTRN	Q7KZI7	MARK2	S1415	S1415N	1415	Missense	central	0	yes	345.256	0.000	EPSD	ICGC;COSMIC	271.430	Loss
CAMK_CAMKL_MARK_MARK2_ST	P46939	UTRN	Q7KZI7	MARK2	S1486	L1485F	1485	Missense	proximal	-1	no	289.084	279.042	EPSD	ICGC;COSMIC	271.430	Down-regulation
CAMK_CAMKL_MARK_MARK2_ST	P46939	UTRN	Q7KZI7	MARK2	S1695	E1688Q	1688	Missense	distal	-7	no	306.864	306.843	EPSD	ICGC;COSMIC	271.430	Down-regulation
CAMK_CAMKL_MARK_MARK2_ST	P46939	UTRN	Q7KZI7	MARK2	S1695	A1700S	1700	Missense	distal	5	no	306.864	319.723	EPSD	ICGC	271.430	Up-regulation
CAMK_CAMKL_MARK_MARK2_ST	P46939	UTRN	Q7KZI7	MARK2	S1695	E1688K	1688	Missense	distal	-7	no	306.864	306.818	EPSD	ICGC	271.430	Down-regulation
CAMK_CAMKL_MARK_MARK2_ST	P46939	UTRN	Q7KZI7	MARK2	S1795	V1789L	1789	Missense	distal	-6	no	293.587	294.669	EPSD	ICGC;COSMIC	271.430	Up-regulation
CAMK_CAMKL_MARK_MARK2_ST	P46939	UTRN	Q7KZI7	MARK2	T2112	M2107I	2107	Missense	distal	-5	no	309.938	314.845	EPSD	ICGC	271.430	Up-regulation
CAMK_CAMKL_MARK_MARK2_ST	P46939	UTRN	Q7KZI7	MARK2	T2112	N2118T	2118	Missense	distal	6	no	309.938	302.818	EPSD	ICGC;GDSC;CCLE	271.430	Down-regulation
CAMK_CAMKL_MARK_MARK2_ST	P46939	UTRN	Q7KZI7	MARK2	S2211	D2214H	2214	Missense	distal	3	no	324.528	262.980	EPSD	ICGC;COSMIC	271.430	Loss
CAMK_CAMKL_MARK_MARK2_ST	P46939	UTRN	Q7KZI7	MARK2	S2567	M2566I	2566	Missense	proximal	-1	no	286.958	290.814	EPSD	ICGC;COSMIC	271.430	Up-regulation
CAMK_CAMKL_MARK_MARK2_ST	P46939	UTRN	Q7KZI7	MARK2	S2666	E2673D	2673	Missense	distal	7	no	315.156	316.181	EPSD	ICGC	271.430	Up-regulation
CAMK_CAMKL_MARK_MARK2_ST	P46939	UTRN	Q7KZI7	MARK2	S2851	V2858A	2858	Missense	distal	7	no	305.310	287.415	EPSD	ICGC;COSMIC	271.430	Down-regulation
CAMK_CAMKL_MARK_MARK2_ST	P46939	UTRN	Q7KZI7	MARK2	S2851	L2852F	2852	Missense	proximal	1	no	305.310	297.799	EPSD	ICGC;COSMIC	271.430	Down-regulation
CAMK_CAMKL_MARK_MARK2_ST	P46939	UTRN	Q7KZI7	MARK2	S2851	Q2850E	2850	Missense	proximal	-1	no	305.310	315.922	EPSD	ICGC;COSMIC	271.430	Up-regulation
CAMK_CAMKL_MARK_MARK2_ST	Q9UQL6	HDAC5	Q7KZI7	MARK2	S229	S225R	225	Missense	distal	-4	no	274.524	274.125	EPSD	ICGC;COSMIC	271.430	Down-regulation
CAMK_CAMKL_MARK_MARK2_ST	Q6WKZ4	RAB11FIP1	Q7KZI7	MARK2	S184	G185C	185	Missense	proximal	1	no	274.526	278.153	EPSD	ICGC;COSMIC	271.430	Up-regulation
CAMK_CAMKL_MARK_MARK2_ST	Q6WKZ4	RAB11FIP1	Q7KZI7	MARK2	S199	P198L	198	Missense	proximal	-1	no	270.350	290.117	EPSD	ICGC;COSMIC	271.430	Gain
CAMK_CAMKL_MARK_MARK2_ST	Q6WKZ4	RAB11FIP1	Q7KZI7	MARK2	S234	S241F	241	Missense	distal	7	no	361.908	364.021	PhosphoSitePlus	ICGC;COSMIC	271.430	Up-regulation
CAMK_CAMKL_MARK_MARK2_ST	Q6WKZ4	RAB11FIP1	Q7KZI7	MARK2	S315	G321W	321	Missense	distal	6	no	297.961	282.305	EPSD	ICGC;COSMIC	271.430	Down-regulation
CAMK_CAMKL_MARK_MARK2_ST	Q6WKZ4	RAB11FIP1	Q7KZI7	MARK2	S660	A663V	663	Missense	distal	3	no	305.734	337.402	EPSD	ICGC;COSMIC	271.430	Up-regulation
CAMK_CAMKL_MARK_MARK2_ST	Q6WKZ4	RAB11FIP1	Q7KZI7	MARK2	S660	K665E	665	Missense	distal	5	no	305.734	283.732	EPSD	ICGC;COSMIC	271.430	Down-regulation
CAMK_CAMKL_MARK_MARK2_ST	Q6WKZ4	RAB11FIP1	Q7KZI7	MARK2	S685	L687R	687	Missense	proximal	2	no	270.905	283.902	EPSD	ICGC	271.430	Gain
CAMK_CAMKL_MARK_MARK2_ST	Q6WKZ4	RAB11FIP1	Q7KZI7	MARK2	S719	Q724K	724	Missense	distal	5	no	280.407	293.314	EPSD	ICGC	271.430	Up-regulation
CAMK_CAMKL_MARK_MARK2_ST	Q6WKZ4	RAB11FIP1	Q7KZI7	MARK2	S733	L730I	730	Missense	distal	-3	no	275.763	188.095	EPSD	ICGC	271.430	Loss
CAMK_CAMKL_MARK_MARK2_ST	Q6WKZ4	RAB11FIP1	Q7KZI7	MARK2	S939	D940V	940	Missense	proximal	1	no	265.406	276.196	EPSD	ICGC	271.430	Gain
CAMK_CAMKL_MARK_MARK2_ST	Q6WKZ4	RAB11FIP1	Q7KZI7	MARK2	S958	A953V	953	Missense	distal	-5	no	314.151	327.289	EPSD	ICGC	271.430	Up-regulation
CAMK_CAMKL_MARK_MARK2_ST	Q6WKZ4	RAB11FIP1	Q7KZI7	MARK2	S1162	T1169N	1169	Missense	distal	7	no	266.361	274.057	EPSD	ICGC;COSMIC	271.430	Gain
CAMK_CAMKL_MARK_MARK2_ST	Q6WKZ4	RAB11FIP1	Q7KZI7	MARK2	S1162	V1161F	1161	Missense	proximal	-1	no	266.361	281.480	EPSD	ICGC;COSMIC	271.430	Gain
CMGC_CLK_CLK2_ST	O60829	PAGE4	P49760	CLK2	S9	A3P	3	Missense	distal	-6	no	0.008	0.006	EPSD;PhosphoSitePlus	ICGC	0.005	Down-regulation
CMGC_CLK_CLK2_ST	O60829	PAGE4	P49760	CLK2	S79	E83Q	83	Missense	distal	4	no	0.008	0.007	EPSD;PhosphoSitePlus	ICGC	0.005	Down-regulation
CMGC_CLK_CLK2_ST	O60829	PAGE4	P49760	CLK2	T85	E83Q	83	Missense	proximal	-2	no	0.005	0.004	EPSD;PhosphoSitePlus	ICGC	0.005	Loss
CMGC_CLK_CLK2_ST	O60829	PAGE4	P49760	CLK2	T85	P89H	89	Missense	distal	4	no	0.005	0.006	EPSD;PhosphoSitePlus	ICGC;COSMIC	0.005	Up-regulation
AGC_SGK_SGK1_ST	O00213	APBB1	O00141	SGK1	T92	A96E	96	Missense	distal	4	no	9.998	9.881	EPSD	ICGC	9.140	Down-regulation
AGC_SGK_SGK1_ST	O00213	APBB1	O00141	SGK1	T92	R89S	89	Missense	distal	-3	no	9.998	3.092	EPSD	ICGC;COSMIC	9.140	Loss
AGC_SGK_SGK1_ST	Q96PU5	NEDD4L	O00141	SGK1	S256	E262K	262	Missense	distal	6	no	12.531	12.718	EPSD	ICGC;COSMIC	9.140	Up-regulation
AGC_SGK_SGK1_ST	Q96PU5	NEDD4L	O00141	SGK1	S256	E257V	257	Missense	proximal	1	no	12.531	12.626	EPSD	ICGC	9.140	Up-regulation
AGC_SGK_SGK1_ST	Q96PU5	NEDD4L	O00141	SGK1	S256	R250S	250	Missense	distal	-6	no	12.531	12.574	EPSD	ICGC;COSMIC	9.140	Up-regulation
AGC_SGK_SGK1_ST	Q96PU5	NEDD4L	O00141	SGK1	T318	G323W	323	Missense	distal	5	no	12.455	12.415	EPSD	ICGC;COSMIC	9.140	Down-regulation
AGC_SGK_SGK1_ST	Q96PU5	NEDD4L	O00141	SGK1	S335	S328F	328	Missense	distal	-7	no	9.132	10.571	EPSD	ICGC;COSMIC	9.140	Gain
AGC_SGK_SGK1_ST	Q96PU5	NEDD4L	O00141	SGK1	S340	V347D	347	Missense	distal	7	no	16.090	15.861	EPSD	ICGC;COSMIC	9.140	Down-regulation
AGC_SGK_SGK1_ST	Q96PU5	NEDD4L	O00141	SGK1	S342	V347D	347	Missense	distal	5	no	16.913	16.962	PhosphoSitePlus;EPSD	ICGC;COSMIC	9.140	Up-regulation
AGC_SGK_SGK1_ST	Q96PU5	NEDD4L	O00141	SGK1	S342	E349K	349	Missense	distal	7	no	16.913	16.495	PhosphoSitePlus;EPSD	ICGC;COSMIC	9.140	Down-regulation
AGC_SGK_SGK1_ST	Q96PU5	NEDD4L	O00141	SGK1	S365	P359T	359	Missense	distal	-6	no	10.437	10.620	EPSD	ICGC;COSMIC	9.140	Up-regulation
AGC_SGK_SGK1_ST	Q96PU5	NEDD4L	O00141	SGK1	S446	R442Q	442	Missense	distal	-4	no	10.603	10.141	EPSD	ICGC	9.140	Down-regulation
AGC_SGK_SGK1_ST	Q96PU5	NEDD4L	O00141	SGK1	S448	R442Q	442	Missense	distal	-6	no	16.907	16.786	EPSD;PhosphoSitePlus	ICGC	9.140	Down-regulation
AGC_SGK_SGK1_ST	Q96PU5	NEDD4L	O00141	SGK1	T473	A469V	469	Missense	distal	-4	no	9.493	7.958	EPSD	ICGC	9.140	Loss
AGC_SGK_SGK1_ST	P49815	TSC2	O00141	SGK1	S311	S315L	315	Missense	distal	4	no	13.397	13.255	EPSD	ICGC;COSMIC	9.140	Down-regulation
AGC_SGK_SGK1_ST	P49815	TSC2	O00141	SGK1	S311	R308L	308	Missense	distal	-3	no	13.397	8.049	EPSD	ICGC;COSMIC	9.140	Loss
AGC_SGK_SGK1_ST	P49815	TSC2	O00141	SGK1	S311	A306D	306	Missense	distal	-5	no	13.397	10.277	EPSD	ICGC;COSMIC	9.140	Down-regulation
AGC_SGK_SGK1_ST	P49815	TSC2	O00141	SGK1	S540	R537L	537	Missense	distal	-3	no	9.702	4.354	EPSD	ICGC	9.140	Loss
AGC_SGK_SGK1_ST	P49815	TSC2	O00141	SGK1	S932	E929K	929	Missense	distal	-3	no	5.052	9.395	EPSD	ICGC	9.140	Gain
AGC_SGK_SGK1_ST	P49815	TSC2	O00141	SGK1	S939	R934M	934	Missense	distal	-5	no	14.517	7.129	EPSD;PhosphoSitePlus	ICGC;COSMIC	9.140	Loss
AGC_SGK_SGK1_ST	P49815	TSC2	O00141	SGK1	S979	R976Q	976	Missense	distal	-3	no	11.403	0.741	EPSD	ICGC;COSMIC	9.140	Loss
AGC_SGK_SGK1_ST	P49815	TSC2	O00141	SGK1	S979	R978C	978	Missense	proximal	-1	no	11.403	11.283	EPSD	ICGC;COSMIC	9.140	Down-regulation
AGC_SGK_SGK1_ST	P49815	TSC2	O00141	SGK1	S979	E973K	973	Missense	distal	-6	no	11.403	11.698	EPSD	ICGC;COSMIC	9.140	Up-regulation
AGC_SGK_SGK1_ST	P49815	TSC2	O00141	SGK1	S979	R976G	976	Missense	distal	-3	no	11.403	4.847	EPSD	ICGC	9.140	Loss
AGC_SGK_SGK1_ST	P49815	TSC2	O00141	SGK1	S979	V986M	986	Missense	distal	7	no	11.403	11.202	EPSD	ICGC	9.140	Down-regulation
AGC_SGK_SGK1_ST	P49815	TSC2	O00141	SGK1	S981	R976Q	976	Missense	distal	-5	no	15.889	7.738	EPSD;PhosphoSitePlus	ICGC;COSMIC	9.140	Loss
AGC_SGK_SGK1_ST	P49815	TSC2	O00141	SGK1	S981	R978C	978	Missense	distal	-3	no	15.889	7.827	EPSD;PhosphoSitePlus	ICGC;COSMIC	9.140	Loss
AGC_SGK_SGK1_ST	P49815	TSC2	O00141	SGK1	S981	R988L	988	Missense	distal	7	no	15.889	16.179	EPSD;PhosphoSitePlus	ICGC	9.140	Up-regulation
AGC_SGK_SGK1_ST	P49815	TSC2	O00141	SGK1	S981	R988H	988	Missense	distal	7	no	15.889	15.973	EPSD;PhosphoSitePlus	ICGC	9.140	Up-regulation
AGC_SGK_SGK1_ST	P49815	TSC2	O00141	SGK1	S981	R976G	976	Missense	distal	-5	no	15.889	10.528	EPSD;PhosphoSitePlus	ICGC	9.140	Down-regulation
AGC_SGK_SGK1_ST	P49815	TSC2	O00141	SGK1	S981	V986M	986	Missense	distal	5	no	15.889	15.920	EPSD;PhosphoSitePlus	ICGC	9.140	Up-regulation
AGC_SGK_SGK1_ST	P49815	TSC2	O00141	SGK1	S983	R976Q	976	Missense	distal	-7	no	11.799	12.328	EPSD	ICGC;COSMIC	9.140	Up-regulation
AGC_SGK_SGK1_ST	P49815	TSC2	O00141	SGK1	S983	R978C	978	Missense	distal	-5	no	11.799	5.537	EPSD	ICGC;COSMIC	9.140	Loss
AGC_SGK_SGK1_ST	P49815	TSC2	O00141	SGK1	S983	R988L	988	Missense	distal	5	no	11.799	11.770	EPSD	ICGC	9.140	Down-regulation
AGC_SGK_SGK1_ST	P49815	TSC2	O00141	SGK1	S983	R988H	988	Missense	distal	5	no	11.799	11.780	EPSD	ICGC	9.140	Down-regulation
AGC_SGK_SGK1_ST	P49815	TSC2	O00141	SGK1	S983	R976G	976	Missense	distal	-7	no	11.799	12.686	EPSD	ICGC	9.140	Up-regulation
AGC_SGK_SGK1_ST	P49815	TSC2	O00141	SGK1	S983	V986M	986	Missense	distal	3	no	11.799	12.107	EPSD	ICGC	9.140	Up-regulation
AGC_SGK_SGK1_ST	P49815	TSC2	O00141	SGK1	T993	R988L	988	Missense	distal	-5	no	17.102	12.874	EPSD	ICGC	9.140	Down-regulation
AGC_SGK_SGK1_ST	P49815	TSC2	O00141	SGK1	T993	R988H	988	Missense	distal	-5	no	17.102	9.770	EPSD	ICGC	9.140	Down-regulation
AGC_SGK_SGK1_ST	P49815	TSC2	O00141	SGK1	T993	V986M	986	Missense	distal	-7	no	17.102	16.635	EPSD	ICGC	9.140	Down-regulation
AGC_SGK_SGK1_ST	P49815	TSC2	O00141	SGK1	S1007	S1002Y	1002	Missense	distal	-5	no	8.529	9.258	EPSD	ICGC;COSMIC	9.140	Gain
AGC_SGK_SGK1_ST	P49815	TSC2	O00141	SGK1	S1338	S1336L	1336	Missense	proximal	-2	no	13.956	13.844	EPSD	ICGC;COSMIC	9.140	Down-regulation
AGC_SGK_SGK1_ST	P49815	TSC2	O00141	SGK1	S1340	S1336L	1336	Missense	distal	-4	no	12.632	11.912	EPSD	ICGC;COSMIC	9.140	Down-regulation
AGC_SGK_SGK1_ST	O60343	TBC1D4	O00141	SGK1	S133	S133R	133	Missense	central	0	yes	9.772	0.000	EPSD	ICGC;COSMIC	9.140	Loss
AGC_SGK_SGK1_ST	O60343	TBC1D4	O00141	SGK1	S133	A140D	140	Missense	distal	7	no	9.772	9.946	EPSD	ICGC	9.140	Up-regulation
AGC_SGK_SGK1_ST	O60343	TBC1D4	O00141	SGK1	S133	T137S	137	Missense	distal	4	no	9.772	9.828	EPSD	ICGC	9.140	Up-regulation
AGC_SGK_SGK1_ST	O60343	TBC1D4	O00141	SGK1	S304	R299Q	299	Missense	distal	-5	no	13.809	5.658	EPSD	ICGC;COSMIC;CCLE	9.140	Loss
AGC_SGK_SGK1_ST	O60343	TBC1D4	O00141	SGK1	S341	A340T	340	Missense	proximal	-1	no	18.973	18.972	EPSD;PhosphoSitePlus	ICGC;COSMIC	9.140	Down-regulation
AGC_SGK_SGK1_ST	O60343	TBC1D4	O00141	SGK1	S341	Q347E	347	Missense	distal	6	no	18.973	19.010	EPSD;PhosphoSitePlus	ICGC;COSMIC	9.140	Up-regulation
AGC_SGK_SGK1_ST	O60343	TBC1D4	O00141	SGK1	S341	P335S	335	Missense	distal	-6	no	18.973	19.241	EPSD;PhosphoSitePlus	ICGC	9.140	Up-regulation
AGC_SGK_SGK1_ST	O60343	TBC1D4	O00141	SGK1	S341	A340V	340	Missense	proximal	-1	no	18.973	18.787	EPSD;PhosphoSitePlus	ICGC;COSMIC	9.140	Down-regulation
AGC_SGK_SGK1_ST	O60343	TBC1D4	O00141	SGK1	S445	A442V	442	Missense	distal	-3	no	9.160	2.727	EPSD	ICGC	9.140	Loss
AGC_SGK_SGK1_ST	O60343	TBC1D4	O00141	SGK1	S445	Q444K	444	Missense	proximal	-1	no	9.160	9.325	EPSD	ICGC	9.140	Up-regulation
AGC_SGK_SGK1_ST	O60343	TBC1D4	O00141	SGK1	S551	E546K	546	Missense	distal	-5	no	7.135	10.666	EPSD	ICGC	9.140	Gain
AGC_SGK_SGK1_ST	O60343	TBC1D4	O00141	SGK1	T568	N561H	561	Missense	distal	-7	no	14.705	14.900	EPSD;PhosphoSitePlus	ICGC	9.140	Up-regulation
AGC_SGK_SGK1_ST	O60343	TBC1D4	O00141	SGK1	T568	K562R	562	Missense	distal	-6	no	14.705	14.559	EPSD;PhosphoSitePlus	ICGC	9.140	Down-regulation
AGC_SGK_SGK1_ST	O60343	TBC1D4	O00141	SGK1	S588	L586I	586	Missense	proximal	-2	no	17.590	17.249	EPSD;PhosphoSitePlus	ICGC	9.140	Down-regulation
AGC_SGK_SGK1_ST	O60343	TBC1D4	O00141	SGK1	S588	R585Q	585	Missense	distal	-3	no	17.590	6.928	EPSD;PhosphoSitePlus	ICGC	9.140	Loss
AGC_SGK_SGK1_ST	O60343	TBC1D4	O00141	SGK1	S588	R585G	585	Missense	distal	-3	no	17.590	11.034	EPSD;PhosphoSitePlus	ICGC	9.140	Down-regulation
AGC_SGK_SGK1_ST	O60343	TBC1D4	O00141	SGK1	T642	Q635K	635	Missense	distal	-7	no	17.501	16.643	EPSD;PhosphoSitePlus	ICGC	9.140	Down-regulation
AGC_SGK_SGK1_ST	O60343	TBC1D4	O00141	SGK1	T642	P646Q	646	Missense	distal	4	no	17.501	17.607	EPSD;PhosphoSitePlus	ICGC;COSMIC	9.140	Up-regulation
AGC_SGK_SGK1_ST	O60343	TBC1D4	O00141	SGK1	S644	P646Q	646	Missense	proximal	2	no	9.429	9.328	EPSD	ICGC;COSMIC	9.140	Down-regulation
AGC_SGK_SGK1_ST	O60343	TBC1D4	O00141	SGK1	S666	G659W	659	Missense	distal	-7	no	10.493	10.721	EPSD;PhosphoSitePlus	ICGC;COSMIC	9.140	Up-regulation
AGC_SGK_SGK1_ST	O60343	TBC1D4	O00141	SGK1	S666	G659V	659	Missense	distal	-7	no	10.493	10.774	EPSD;PhosphoSitePlus	ICGC;COSMIC	9.140	Up-regulation
AGC_SGK_SGK1_ST	O60343	TBC1D4	O00141	SGK1	T701	P706T	706	Missense	distal	5	no	9.540	9.590	EPSD	ICGC;COSMIC	9.140	Up-regulation
AGC_SGK_SGK1_ST	O60343	TBC1D4	O00141	SGK1	S704	P706T	706	Missense	proximal	2	no	12.441	12.453	EPSD	ICGC;COSMIC	9.140	Up-regulation
AGC_SGK_SGK1_ST	Q9UN36	NDRG2	O00141	SGK1	S328	R329C	329	Missense	proximal	1	no	9.840	9.839	EPSD	ICGC	9.140	Down-regulation
AGC_SGK_SGK1_ST	Q9UN36	NDRG2	O00141	SGK1	T330	R329C	329	Missense	proximal	-1	no	17.630	17.510	EPSD;PhosphoSitePlus	ICGC	9.140	Down-regulation
AGC_SGK_SGK1_ST	Q9UN36	NDRG2	O00141	SGK1	S332	R329C	329	Missense	distal	-3	no	20.303	12.241	EPSD;PhosphoSitePlus	ICGC	9.140	Down-regulation
AGC_SGK_SGK1_ST	Q9UN36	NDRG2	O00141	SGK1	T334	R329C	329	Missense	distal	-5	no	13.398	7.136	EPSD	ICGC	9.140	Loss
AGC_SGK_SGK1_ST	Q9UN36	NDRG2	O00141	SGK1	S346	S346L	346	Missense	central	0	yes	14.496	0.000	EPSD;PhosphoSitePlus	ICGC;COSMIC	9.140	Loss
AGC_SGK_SGK1_ST	Q9UN36	NDRG2	O00141	SGK1	S346	S344C	344	Missense	proximal	-2	no	14.496	14.369	EPSD;PhosphoSitePlus	ICGC	9.140	Down-regulation
AGC_SGK_SGK1_ST	Q9UN36	NDRG2	O00141	SGK1	T348	S346L	346	Missense	proximal	-2	no	19.728	19.616	PhosphoSitePlus;EPSD	ICGC;COSMIC	9.140	Down-regulation
AGC_SGK_SGK1_ST	Q9UN36	NDRG2	O00141	SGK1	T348	S344C	344	Missense	distal	-4	no	19.728	19.236	PhosphoSitePlus;EPSD	ICGC	9.140	Down-regulation
AGC_SGK_SGK1_ST	Q9UN36	NDRG2	O00141	SGK1	S350	S346L	346	Missense	distal	-4	no	16.482	15.762	EPSD	ICGC;COSMIC	9.140	Down-regulation
AGC_SGK_SGK1_ST	Q9UN36	NDRG2	O00141	SGK1	S350	S344C	344	Missense	distal	-6	no	16.482	16.375	EPSD	ICGC	9.140	Down-regulation
AGC_SGK_SGK1_ST	Q9UN36	NDRG2	O00141	SGK1	S352	S346L	346	Missense	distal	-6	no	9.627	9.441	EPSD	ICGC;COSMIC	9.140	Down-regulation
AGC_SGK_SGK1_ST	P16220	CREB1	O00141	SGK1	S133	D140A	140	Missense	distal	7	no	15.615	15.440	PhosphoSitePlus	ICGC;COSMIC	9.140	Down-regulation
AGC_SGK_SGK1_ST	P10636	MAPT	O00141	SGK1	T167	P160L	160	Missense	distal	-7	no	10.219	9.974	EPSD	ICGC;COSMIC	9.140	Down-regulation
AGC_SGK_SGK1_ST	P10636	MAPT	O00141	SGK1	T167	R164T	164	Missense	distal	-3	no	10.219	4.872	EPSD	ICGC;COSMIC	9.140	Loss
AGC_SGK_SGK1_ST	P10636	MAPT	O00141	SGK1	T167	A166T	166	Missense	proximal	-1	no	10.219	10.218	EPSD	ICGC	9.140	Down-regulation
AGC_SGK_SGK1_ST	P10636	MAPT	O00141	SGK1	S171	R164T	164	Missense	distal	-7	no	12.821	13.057	EPSD	ICGC;COSMIC	9.140	Up-regulation
AGC_SGK_SGK1_ST	P10636	MAPT	O00141	SGK1	S171	A166T	166	Missense	distal	-5	no	12.821	12.706	EPSD	ICGC	9.140	Down-regulation
AGC_SGK_SGK1_ST	P10636	MAPT	O00141	SGK1	S214	G208C	208	Missense	distal	-6	no	13.460	13.560	PhosphoSitePlus	ICGC;COSMIC	9.140	Up-regulation
AGC_SGK_SGK1_ST	P10636	MAPT	O00141	SGK1	S214	R211S	211	Missense	distal	-3	no	13.460	6.554	PhosphoSitePlus	ICGC;COSMIC	9.140	Loss
AGC_SGK_SGK1_ST	P10636	MAPT	O00141	SGK1	S214	G213E	213	Missense	proximal	-1	no	13.460	13.527	PhosphoSitePlus	ICGC;COSMIC	9.140	Up-regulation
AGC_SGK_SGK1_ST	P10636	MAPT	O00141	SGK1	S227	V224I	224	Missense	distal	-3	no	8.105	11.281	EPSD	ICGC;COSMIC	9.140	Gain
AGC_SGK_SGK1_ST	P10636	MAPT	O00141	SGK1	S341	T346I	346	Missense	distal	5	no	9.968	9.906	EPSD	ICGC;COSMIC	9.140	Down-regulation
AGC_SGK_SGK1_ST	P10636	MAPT	O00141	SGK1	S341	A337V	337	Missense	distal	-4	no	9.968	8.433	EPSD	ICGC	9.140	Loss
AGC_SGK_SGK1_ST	P10636	MAPT	O00141	SGK1	S341	D345E	345	Missense	distal	4	no	9.968	9.948	EPSD	ICGC;COSMIC	9.140	Down-regulation
AGC_SGK_SGK1_ST	P10636	MAPT	O00141	SGK1	S369	R364W	364	Missense	distal	-5	no	11.179	3.521	EPSD	ICGC;COSMIC	9.140	Loss
AGC_SGK_SGK1_ST	P10636	MAPT	O00141	SGK1	S369	P363L	363	Missense	distal	-6	no	11.179	11.261	EPSD	ICGC	9.140	Up-regulation
AGC_SGK_SGK1_ST	P10636	MAPT	O00141	SGK1	S516	G521R	521	Missense	distal	5	no	12.537	12.577	EPSD	ICGC;COSMIC	9.140	Up-regulation
AGC_SGK_SGK1_ST	P46527	CDKN1B	O00141	SGK1	T157	Q163E	163	Missense	distal	6	no	16.770	16.806	PhosphoSitePlus;EPSD	ICGC;COSMIC	9.140	Up-regulation
AGC_SGK_SGK1_ST	P46527	CDKN1B	O00141	SGK1	T157	S160F	160	Missense	distal	3	no	16.770	15.963	PhosphoSitePlus;EPSD	ICGC;COSMIC	9.140	Down-regulation
AGC_SGK_SGK1_ST	P46527	CDKN1B	O00141	SGK1	T157	T162I	162	Missense	distal	5	no	16.770	16.707	PhosphoSitePlus;EPSD	ICGC;COSMIC	9.140	Down-regulation
AGC_SGK_SGK1_ST	P46527	CDKN1B	O00141	SGK1	T198	G192V	192	Missense	distal	-6	no	12.359	12.125	EPSD;PhosphoSitePlus	ICGC	9.140	Down-regulation
AGC_SGK_SGK1_ST	P46527	CDKN1B	O00141	SGK1	T198	P191H	191	Missense	distal	-7	no	12.359	11.726	EPSD;PhosphoSitePlus	ICGC;COSMIC	9.140	Down-regulation
AGC_SGK_SGK1_ST	O00141	SGK1	O00141	SGK1	S422	F418C	418	Missense	distal	-4	no	7.665	9.349	PhosphoSitePlus	ICGC;COSMIC	9.140	Gain
AGC_SGK_SGK1_ST	Q9Y2V2	CARHSP1	O00141	SGK1	S26	G19W	19	Missense	distal	-7	no	9.859	10.086	EPSD	ICGC;COSMIC	9.140	Up-regulation
AGC_SGK_SGK1_ST	Q9Y2V2	CARHSP1	O00141	SGK1	T50	S52L	52	Missense	proximal	2	no	12.625	12.912	EPSD	ICGC;COSMIC	9.140	Up-regulation
AGC_SGK_SGK1_ST	Q9Y2V2	CARHSP1	O00141	SGK1	T50	P44H	44	Missense	distal	-6	no	12.625	12.770	EPSD	ICGC;COSMIC	9.140	Up-regulation
AGC_SGK_SGK1_ST	Q9Y2V2	CARHSP1	O00141	SGK1	S52	S52L	52	Missense	central	0	yes	16.115	0.000	PhosphoSitePlus	ICGC;COSMIC	9.140	Loss
AGC_SGK_SGK1_ST	Q9Y2V2	CARHSP1	O00141	SGK1	T54	S52L	52	Missense	proximal	-2	no	9.750	9.638	EPSD	ICGC;COSMIC	9.140	Down-regulation
AGC_SGK_SGK1_ST	Q9H4A3	WNK1	O00141	SGK1	S19	K26N	26	Missense	distal	7	no	9.030	9.248	EPSD	ICGC	9.140	Gain
AGC_SGK_SGK1_ST	Q9H4A3	WNK1	O00141	SGK1	T60	R57H	57	Missense	distal	-3	no	16.959	7.341	PhosphoSitePlus	ICGC;COSMIC;GDSC;CCLE	9.140	Loss
AGC_SGK_SGK1_ST	Q9H4A3	WNK1	O00141	SGK1	T60	G67E	67	Missense	distal	7	no	16.959	16.885	PhosphoSitePlus	ICGC	9.140	Down-regulation
AGC_SGK_SGK1_ST	Q9H4A3	WNK1	O00141	SGK1	T60	E53D	53	Missense	distal	-7	no	16.959	16.819	PhosphoSitePlus	ICGC	9.140	Down-regulation
AGC_SGK_SGK1_ST	Q9H4A3	WNK1	O00141	SGK1	T60	R66S	66	Missense	distal	6	no	16.959	17.017	PhosphoSitePlus	ICGC;GDSC;CCLE	9.140	Up-regulation
AGC_SGK_SGK1_ST	Q9H4A3	WNK1	O00141	SGK1	T60	H59N	59	Missense	proximal	-1	no	16.959	16.987	PhosphoSitePlus	ICGC;COSMIC	9.140	Up-regulation
AGC_SGK_SGK1_ST	Q9H4A3	WNK1	O00141	SGK1	T60	R56C	56	Missense	distal	-4	no	16.959	16.773	PhosphoSitePlus	ICGC;COSMIC	9.140	Down-regulation
AGC_SGK_SGK1_ST	Q9H4A3	WNK1	O00141	SGK1	T60	R55G	55	Missense	distal	-5	no	16.959	11.599	PhosphoSitePlus	ICGC;COSMIC	9.140	Down-regulation
AGC_SGK_SGK1_ST	Q9H4A3	WNK1	O00141	SGK1	T60	T60I	60	Missense	central	0	yes	16.959	0.000	PhosphoSitePlus	ICGC;COSMIC	9.140	Loss
AGC_SGK_SGK1_ST	Q9H4A3	WNK1	O00141	SGK1	T71	A70V	70	Missense	proximal	-1	no	11.162	10.976	EPSD	ICGC;COSMIC	9.140	Down-regulation
AGC_SGK_SGK1_ST	Q9H4A3	WNK1	O00141	SGK1	T71	G67E	67	Missense	distal	-4	no	11.162	11.186	EPSD	ICGC	9.140	Up-regulation
AGC_SGK_SGK1_ST	Q9H4A3	WNK1	O00141	SGK1	T71	R66S	66	Missense	distal	-5	no	11.162	5.917	EPSD	ICGC;GDSC;CCLE	9.140	Loss
AGC_SGK_SGK1_ST	Q9H4A3	WNK1	O00141	SGK1	S185	P178L	178	Missense	distal	-7	no	9.265	9.019	EPSD	ICGC	9.140	Loss
AGC_SGK_SGK1_ST	Q9H4A3	WNK1	O00141	SGK1	S185	P179S	179	Missense	distal	-6	no	9.265	9.533	EPSD	ICGC;COSMIC	9.140	Up-regulation
AGC_SGK_SGK1_ST	Q9H4A3	WNK1	O00141	SGK1	S1105	S1105R	1105	Missense	central	0	yes	16.009	0.000	EPSD	ICGC	9.140	Loss
AGC_SGK_SGK1_ST	Q9H4A3	WNK1	O00141	SGK1	S1108	S1105R	1105	Missense	distal	-3	no	10.429	17.335	EPSD	ICGC	9.140	Up-regulation
AGC_SGK_SGK1_ST	Q9H4A3	WNK1	O00141	SGK1	S1110	S1105R	1105	Missense	distal	-5	no	10.760	16.005	EPSD	ICGC	9.140	Up-regulation
AGC_SGK_SGK1_ST	Q9H4A3	WNK1	O00141	SGK1	S1893	T1889A	1889	Missense	distal	-4	no	11.262	11.675	EPSD	ICGC	9.140	Up-regulation
AGC_SGK_SGK1_ST	Q9H4A3	WNK1	O00141	SGK1	S1893	S1899F	1899	Missense	distal	6	no	11.262	10.812	EPSD	ICGC	9.140	Down-regulation
AGC_SGK_SGK1_ST	Q9BUB5	MKNK1	O00141	SGK1	T37	R32W	32	Missense	distal	-5	no	11.035	3.378	EPSD	ICGC	9.140	Loss
AGC_SGK_SGK1_ST	Q9BUB5	MKNK1	O00141	SGK1	S39	R32W	32	Missense	distal	-7	no	8.128	9.242	EPSD	ICGC	9.140	Gain
AGC_SGK_SGK1_ST	O43524	FOXO3	O00141	SGK1	S30	S26C	26	Missense	distal	-4	no	9.790	9.298	EPSD	ICGC;COSMIC	9.140	Down-regulation
AGC_SGK_SGK1_ST	O43524	FOXO3	O00141	SGK1	T32	S26C	26	Missense	distal	-6	no	15.657	15.550	EPSD	ICGC;COSMIC	9.140	Down-regulation
AGC_SGK_SGK1_ST	O43524	FOXO3	O00141	SGK1	S75	G80S	80	Missense	distal	5	no	10.869	10.922	EPSD	ICGC;COSMIC	9.140	Up-regulation
AGC_SGK_SGK1_ST	O43524	FOXO3	O00141	SGK1	S181	P174L	174	Missense	distal	-7	no	9.936	9.691	EPSD	ICGC;COSMIC	9.140	Down-regulation
AGC_SGK_SGK1_ST	O43524	FOXO3	O00141	SGK1	S181	P174T	174	Missense	distal	-7	no	9.936	9.246	EPSD	ICGC;COSMIC	9.140	Down-regulation
AGC_SGK_SGK1_ST	O43524	FOXO3	O00141	SGK1	S181	K176R	176	Missense	distal	-5	no	9.936	14.479	EPSD	ICGC;COSMIC	9.140	Up-regulation
AGC_SGK_SGK1_ST	O43524	FOXO3	O00141	SGK1	S253	R249L	249	Missense	distal	-4	no	17.222	16.807	EPSD	ICGC;COSMIC	9.140	Down-regulation
AGC_SGK_SGK1_ST	O43524	FOXO3	O00141	SGK1	S315	A317T	317	Missense	proximal	2	no	19.864	19.998	PhosphoSitePlus	ICGC;COSMIC	9.140	Up-regulation
AGC_SGK_SGK1_ST	O43524	FOXO3	O00141	SGK1	S318	A317T	317	Missense	proximal	-1	no	10.089	10.088	EPSD	ICGC;COSMIC	9.140	Down-regulation
AGC_SGK_SGK1_ST	O43524	FOXO3	O00141	SGK1	S413	P415L	415	Missense	proximal	2	no	10.023	10.130	EPSD	ICGC;COSMIC;GDSC	9.140	Up-regulation
AGC_SGK_SGK1_ST	O43524	FOXO3	O00141	SGK1	S413	G420S	420	Missense	distal	7	no	10.023	9.638	EPSD	ICGC;COSMIC	9.140	Down-regulation
AGC_SGK_SGK1_ST	O43524	FOXO3	O00141	SGK1	S413	F414L	414	Missense	proximal	1	no	10.023	9.846	EPSD	ICGC	9.140	Down-regulation
AGC_SGK_SGK1_ST	O43524	FOXO3	O00141	SGK1	S421	P415L	415	Missense	distal	-6	no	10.400	10.482	EPSD	ICGC;COSMIC;GDSC	9.140	Up-regulation
AGC_SGK_SGK1_ST	O43524	FOXO3	O00141	SGK1	S421	G424S	424	Missense	distal	3	no	10.400	10.688	EPSD	ICGC;COSMIC	9.140	Up-regulation
AGC_SGK_SGK1_ST	O43524	FOXO3	O00141	SGK1	S421	G420S	420	Missense	proximal	-1	no	10.400	10.601	EPSD	ICGC;COSMIC	9.140	Up-regulation
AGC_SGK_SGK1_ST	O43524	FOXO3	O00141	SGK1	S421	F414L	414	Missense	distal	-7	no	10.400	9.620	EPSD	ICGC	9.140	Down-regulation
AGC_SGK_SGK1_ST	O43524	FOXO3	O00141	SGK1	S551	R548C	548	Missense	distal	-3	no	11.866	3.804	EPSD	ICGC;COSMIC	9.140	Loss
AGC_SGK_SGK1_ST	O43524	FOXO3	O00141	SGK1	S553	R548C	548	Missense	distal	-5	no	13.827	7.565	EPSD	ICGC;COSMIC	9.140	Loss
AGC_SGK_SGK1_ST	P28482	MAPK1	O00141	SGK1	S29	L28I	28	Missense	proximal	-1	no	11.990	11.904	PhosphoSitePlus	ICGC	9.140	Down-regulation
AGC_SGK_SGK1_ST	P28482	MAPK1	O00141	SGK1	S29	R24C	24	Missense	distal	-5	no	11.990	5.728	PhosphoSitePlus	ICGC	9.140	Loss
AGC_SGK_SGK1_ST	P28482	MAPK1	O00141	SGK1	T190	T185K	185	Missense	distal	-5	no	9.577	9.206	EPSD	ICGC	9.140	Down-regulation
AGC_SGK_SGK1_ST	P28482	MAPK1	O00141	SGK1	T190	W192L	192	Missense	proximal	2	no	9.577	9.422	EPSD	ICGC;COSMIC	9.140	Down-regulation
AGC_SGK_SGK1_ST	Q96J92	WNK4	O00141	SGK1	S47	G48E	48	Missense	proximal	1	no	18.127	17.967	EPSD	ICGC;COSMIC	9.140	Down-regulation
AGC_SGK_SGK1_ST	Q96J92	WNK4	O00141	SGK1	S63	S64L	64	Missense	proximal	1	no	12.812	12.870	EPSD	ICGC;COSMIC	9.140	Up-regulation
AGC_SGK_SGK1_ST	Q96J92	WNK4	O00141	SGK1	S63	S63I	63	Missense	central	0	yes	12.812	0.000	EPSD	ICGC;COSMIC	9.140	Loss
AGC_SGK_SGK1_ST	Q96J92	WNK4	O00141	SGK1	S63	S56F	56	Missense	distal	-7	no	12.812	14.251	EPSD	ICGC	9.140	Up-regulation
AGC_SGK_SGK1_ST	Q96J92	WNK4	O00141	SGK1	S63	G68V	68	Missense	distal	5	no	12.812	12.774	EPSD	ICGC;COSMIC	9.140	Down-regulation
AGC_SGK_SGK1_ST	Q96J92	WNK4	O00141	SGK1	S64	S64L	64	Missense	central	0	yes	12.480	0.000	EPSD	ICGC;COSMIC	9.140	Loss
AGC_SGK_SGK1_ST	Q96J92	WNK4	O00141	SGK1	S64	S63I	63	Missense	proximal	-1	no	12.480	12.303	EPSD	ICGC;COSMIC	9.140	Down-regulation
AGC_SGK_SGK1_ST	Q96J92	WNK4	O00141	SGK1	S64	G68V	68	Missense	distal	4	no	12.480	12.406	EPSD	ICGC;COSMIC	9.140	Down-regulation
AGC_SGK_SGK1_ST	Q96J92	WNK4	O00141	SGK1	S331	R329C	329	Missense	proximal	-2	no	9.204	8.979	EPSD	ICGC;COSMIC;CCLE	9.140	Loss
AGC_SGK_SGK1_ST	Q96J92	WNK4	O00141	SGK1	T679	S674Y	674	Missense	distal	-5	no	8.671	9.400	EPSD	ICGC;COSMIC	9.140	Gain
AGC_SGK_SGK1_ST	Q96J92	WNK4	O00141	SGK1	S680	S674Y	674	Missense	distal	-6	no	17.705	17.522	EPSD	ICGC;COSMIC	9.140	Down-regulation
AGC_SGK_SGK1_ST	Q96J92	WNK4	O00141	SGK1	S680	R675Q	675	Missense	distal	-5	no	17.705	9.554	EPSD	ICGC;COSMIC	9.140	Down-regulation
AGC_SGK_SGK1_ST	Q96J92	WNK4	O00141	SGK1	S680	R677Q	677	Missense	distal	-3	no	17.705	7.042	EPSD	ICGC	9.140	Loss
AGC_SGK_SGK1_ST	Q96J92	WNK4	O00141	SGK1	S680	D686N	686	Missense	distal	6	no	17.705	17.791	EPSD	ICGC;COSMIC	9.140	Up-regulation
AGC_SGK_SGK1_ST	Q96J92	WNK4	O00141	SGK1	S680	S680C	680	Missense	central	0	yes	17.705	0.000	EPSD	ICGC;COSMIC	9.140	Loss
AGC_SGK_SGK1_ST	Q96J92	WNK4	O00141	SGK1	S682	R675Q	675	Missense	distal	-7	no	10.977	11.506	EPSD	ICGC;COSMIC	9.140	Up-regulation
AGC_SGK_SGK1_ST	Q96J92	WNK4	O00141	SGK1	S682	R677Q	677	Missense	distal	-5	no	10.977	2.826	EPSD	ICGC	9.140	Loss
AGC_SGK_SGK1_ST	Q96J92	WNK4	O00141	SGK1	S682	D686N	686	Missense	distal	4	no	10.977	11.073	EPSD	ICGC;COSMIC	9.140	Up-regulation
AGC_SGK_SGK1_ST	Q96J92	WNK4	O00141	SGK1	S682	S680C	680	Missense	proximal	-2	no	10.977	10.849	EPSD	ICGC;COSMIC	9.140	Down-regulation
AGC_SGK_SGK1_ST	Q96J92	WNK4	O00141	SGK1	T1034	G1040C	1040	Missense	distal	6	no	11.674	11.847	EPSD	ICGC	9.140	Up-regulation
AGC_SGK_SGK1_ST	Q96J92	WNK4	O00141	SGK1	T1034	S1039C	1039	Missense	distal	5	no	11.674	11.644	EPSD	ICGC;COSMIC	9.140	Down-regulation
AGC_SGK_SGK1_ST	Q96J92	WNK4	O00141	SGK1	S1054	P1047H	1047	Missense	distal	-7	no	9.145	8.513	EPSD	ICGC;COSMIC	9.140	Loss
AGC_SGK_SGK1_ST	Q96J92	WNK4	O00141	SGK1	S1190	R1188H	1188	Missense	proximal	-2	no	19.299	18.862	EPSD;PhosphoSitePlus	ICGC;COSMIC	9.140	Down-regulation
AGC_SGK_SGK1_ST	Q96J92	WNK4	O00141	SGK1	S1190	R1187H	1187	Missense	distal	-3	no	19.299	9.680	EPSD;PhosphoSitePlus	ICGC;COSMIC	9.140	Down-regulation
AGC_SGK_SGK1_ST	Q96J92	WNK4	O00141	SGK1	S1190	S1197F	1197	Missense	distal	7	no	19.299	19.982	EPSD;PhosphoSitePlus	ICGC	9.140	Up-regulation
AGC_SGK_SGK1_ST	Q96J92	WNK4	O00141	SGK1	S1201	R1204H	1204	Missense	distal	3	no	17.787	17.722	PhosphoSitePlus;EPSD	ICGC	9.140	Down-regulation
AGC_SGK_SGK1_ST	Q96J92	WNK4	O00141	SGK1	S1201	S1197F	1197	Missense	distal	-4	no	17.787	15.612	PhosphoSitePlus;EPSD	ICGC	9.140	Down-regulation
AGC_SGK_SGK1_ST	Q96J92	WNK4	O00141	SGK1	S1217	G1211V	1211	Missense	distal	-6	no	12.893	12.659	EPSD;PhosphoSitePlus	ICGC	9.140	Down-regulation
AGC_SGK_SGK1_ST	Q96J92	WNK4	O00141	SGK1	S1217	T1223S	1223	Missense	distal	6	no	12.893	12.957	EPSD;PhosphoSitePlus	ICGC;COSMIC	9.140	Up-regulation
AGC_SGK_SGK1_ST	Q96J92	WNK4	O00141	SGK1	S1217	G1224D	1224	Missense	distal	7	no	12.893	12.775	EPSD;PhosphoSitePlus	ICGC	9.140	Down-regulation
AGC_SGK_SGK1_ST	Q9Y2I7	PIKFYVE	O00141	SGK1	S105	K112T	112	Missense	distal	7	no	12.382	12.583	EPSD	ICGC;COSMIC	9.140	Up-regulation
AGC_SGK_SGK1_ST	Q9Y2I7	PIKFYVE	O00141	SGK1	S105	R102Q	102	Missense	distal	-3	no	12.382	1.719	EPSD	ICGC	9.140	Loss
AGC_SGK_SGK1_ST	Q9Y2I7	PIKFYVE	O00141	SGK1	S223	A221V	221	Missense	proximal	-2	no	12.585	11.767	EPSD	ICGC	9.140	Down-regulation
AGC_SGK_SGK1_ST	Q9Y2I7	PIKFYVE	O00141	SGK1	S291	V292L	292	Missense	proximal	1	no	10.858	10.790	EPSD	ICGC	9.140	Down-regulation
AGC_SGK_SGK1_ST	Q9Y2I7	PIKFYVE	O00141	SGK1	S291	V290L	290	Missense	proximal	-1	no	10.858	10.988	EPSD	ICGC	9.140	Up-regulation
AGC_SGK_SGK1_ST	Q9Y2I7	PIKFYVE	O00141	SGK1	S307	L311M	311	Missense	distal	4	no	19.074	19.034	EPSD	ICGC	9.140	Down-regulation
AGC_SGK_SGK1_ST	Q9Y2I7	PIKFYVE	O00141	SGK1	S307	N310T	310	Missense	distal	3	no	19.074	19.027	EPSD	ICGC;COSMIC	9.140	Down-regulation
AGC_SGK_SGK1_ST	Q9Y2I7	PIKFYVE	O00141	SGK1	S307	R302Q	302	Missense	distal	-5	no	19.074	10.923	EPSD	ICGC;COSMIC	9.140	Down-regulation
AGC_SGK_SGK1_ST	Q9Y2I7	PIKFYVE	O00141	SGK1	T309	L311M	311	Missense	proximal	2	no	13.071	13.095	EPSD	ICGC	9.140	Up-regulation
AGC_SGK_SGK1_ST	Q9Y2I7	PIKFYVE	O00141	SGK1	T309	N310T	310	Missense	proximal	1	no	13.071	13.145	EPSD	ICGC;COSMIC	9.140	Up-regulation
AGC_SGK_SGK1_ST	Q9Y2I7	PIKFYVE	O00141	SGK1	T309	R302Q	302	Missense	distal	-7	no	13.071	13.600	EPSD	ICGC;COSMIC	9.140	Up-regulation
AGC_SGK_SGK1_ST	Q9Y2I7	PIKFYVE	O00141	SGK1	S316	M320I	320	Missense	distal	4	no	9.785	9.723	EPSD	ICGC;COSMIC	9.140	Down-regulation
AGC_SGK_SGK1_ST	Q9Y2I7	PIKFYVE	O00141	SGK1	S316	L311M	311	Missense	distal	-5	no	9.785	6.626	EPSD	ICGC	9.140	Loss
AGC_SGK_SGK1_ST	Q9Y2I7	PIKFYVE	O00141	SGK1	S316	N310T	310	Missense	distal	-6	no	9.785	9.726	EPSD	ICGC;COSMIC	9.140	Down-regulation
AGC_SGK_SGK1_ST	Q9Y2I7	PIKFYVE	O00141	SGK1	S316	G317C	317	Missense	proximal	1	no	9.785	9.608	EPSD	ICGC;COSMIC	9.140	Down-regulation
AGC_SGK_SGK1_ST	Q9Y2I7	PIKFYVE	O00141	SGK1	S318	M320I	320	Missense	proximal	2	no	15.541	15.655	PhosphoSitePlus	ICGC;COSMIC	9.140	Up-regulation
AGC_SGK_SGK1_ST	Q9Y2I7	PIKFYVE	O00141	SGK1	S318	L311M	311	Missense	distal	-7	no	15.541	15.561	PhosphoSitePlus	ICGC	9.140	Up-regulation
AGC_SGK_SGK1_ST	Q9Y2I7	PIKFYVE	O00141	SGK1	S318	G317C	317	Missense	proximal	-1	no	15.541	15.646	PhosphoSitePlus	ICGC;COSMIC	9.140	Up-regulation
AGC_SGK_SGK1_ST	Q9Y2I7	PIKFYVE	O00141	SGK1	T341	R346H	346	Missense	distal	5	no	10.930	10.911	EPSD	ICGC;COSMIC	9.140	Down-regulation
AGC_SGK_SGK1_ST	Q9Y2I7	PIKFYVE	O00141	SGK1	T341	R346C	346	Missense	distal	5	no	10.930	10.913	EPSD	ICGC;COSMIC	9.140	Down-regulation
AGC_SGK_SGK1_ST	Q9Y2I7	PIKFYVE	O00141	SGK1	S501	R497H	497	Missense	distal	-4	no	11.308	10.890	EPSD	ICGC;COSMIC	9.140	Down-regulation
AGC_SGK_SGK1_ST	Q9Y2I7	PIKFYVE	O00141	SGK1	S501	V500I	500	Missense	proximal	-1	no	11.308	11.351	EPSD	ICGC;COSMIC	9.140	Up-regulation
AGC_SGK_SGK1_ST	Q9Y2I7	PIKFYVE	O00141	SGK1	S501	S495I	495	Missense	distal	-6	no	11.308	10.942	EPSD	ICGC;COSMIC	9.140	Down-regulation
AGC_SGK_SGK1_ST	Q9Y2I7	PIKFYVE	O00141	SGK1	S501	D508Y	508	Missense	distal	7	no	11.308	11.436	EPSD	ICGC	9.140	Up-regulation
AGC_SGK_SGK1_ST	Q9Y2I7	PIKFYVE	O00141	SGK1	S501	V500F	500	Missense	proximal	-1	no	11.308	11.219	EPSD	ICGC	9.140	Down-regulation
AGC_SGK_SGK1_ST	Q9Y2I7	PIKFYVE	O00141	SGK1	S845	A850S	850	Missense	distal	5	no	12.828	12.838	EPSD	ICGC;COSMIC	9.140	Up-regulation
AGC_SGK_SGK1_ST	Q9Y2I7	PIKFYVE	O00141	SGK1	S1111	Q1105H	1105	Missense	distal	-6	no	12.503	12.541	EPSD	ICGC	9.140	Up-regulation
AGC_SGK_SGK1_ST	Q9Y2I7	PIKFYVE	O00141	SGK1	S1111	L1107I	1107	Missense	distal	-4	no	12.503	11.888	EPSD	ICGC	9.140	Down-regulation
AGC_SGK_SGK1_ST	Q9Y2I7	PIKFYVE	O00141	SGK1	S1722	R1728H	1728	Missense	distal	6	no	10.516	10.482	EPSD	ICGC;COSMIC	9.140	Down-regulation
AGC_SGK_SGK1_ST	Q9Y2I7	PIKFYVE	O00141	SGK1	S1745	G1749V	1749	Missense	distal	4	no	9.449	9.376	EPSD	ICGC	9.140	Down-regulation
AGC_SGK_SGK1_ST	Q9Y2I7	PIKFYVE	O00141	SGK1	S1745	G1742V	1742	Missense	distal	-3	no	9.449	4.286	EPSD	ICGC	9.140	Loss
AGC_SGK_SGK1_ST	Q9Y2I7	PIKFYVE	O00141	SGK1	S1745	A1751V	1751	Missense	distal	6	no	9.449	9.156	EPSD	ICGC;COSMIC	9.140	Down-regulation
AGC_SGK_SGK1_ST	Q9Y2I7	PIKFYVE	O00141	SGK1	S2004	S2010C	2010	Missense	distal	6	no	13.672	13.601	EPSD	ICGC	9.140	Down-regulation
AGC_SGK_SGK1_ST	Q9Y2I7	PIKFYVE	O00141	SGK1	S2004	S2010F	2010	Missense	distal	6	no	13.672	13.222	EPSD	ICGC	9.140	Down-regulation
AGC_SGK_SGK1_ST	Q6R327	RICTOR	O00141	SGK1	S21	N19S	19	Missense	proximal	-2	no	19.124	19.277	EPSD	ICGC;COSMIC	9.140	Up-regulation
AGC_SGK_SGK1_ST	Q6R327	RICTOR	O00141	SGK1	S35	N37K	37	Missense	proximal	2	no	13.983	13.874	EPSD	ICGC	9.140	Down-regulation
AGC_SGK_SGK1_ST	Q6R327	RICTOR	O00141	SGK1	T268	Q272K	272	Missense	distal	4	no	10.284	10.561	EPSD	ICGC;COSMIC	9.140	Up-regulation
AGC_SGK_SGK1_ST	Q6R327	RICTOR	O00141	SGK1	T268	P266Q	266	Missense	proximal	-2	no	10.284	10.415	EPSD	ICGC;COSMIC	9.140	Up-regulation
AGC_SGK_SGK1_ST	Q6R327	RICTOR	O00141	SGK1	S383	R380C	380	Missense	distal	-3	no	11.689	3.627	EPSD	ICGC;COSMIC	9.140	Loss
AGC_SGK_SGK1_ST	Q6R327	RICTOR	O00141	SGK1	S383	P385T	385	Missense	proximal	2	no	11.689	11.700	EPSD	ICGC	9.140	Up-regulation
AGC_SGK_SGK1_ST	Q6R327	RICTOR	O00141	SGK1	S383	L377F	377	Missense	distal	-6	no	11.689	11.350	EPSD	ICGC	9.140	Down-regulation
AGC_SGK_SGK1_ST	Q6R327	RICTOR	O00141	SGK1	S383	A381V	381	Missense	proximal	-2	no	11.689	10.871	EPSD	ICGC	9.140	Down-regulation
AGC_SGK_SGK1_ST	Q6R327	RICTOR	O00141	SGK1	S703	T701A	701	Missense	proximal	-2	no	11.742	11.910	EPSD	ICGC	9.140	Up-regulation
AGC_SGK_SGK1_ST	Q6R327	RICTOR	O00141	SGK1	S703	L700R	700	Missense	distal	-3	no	11.742	17.091	EPSD	ICGC;COSMIC	9.140	Up-regulation
AGC_SGK_SGK1_ST	Q6R327	RICTOR	O00141	SGK1	S703	R709G	709	Missense	distal	6	no	11.742	11.556	EPSD	ICGC;COSMIC	9.140	Down-regulation
AGC_SGK_SGK1_ST	Q6R327	RICTOR	O00141	SGK1	S810	L809F	809	Missense	proximal	-1	no	12.466	12.247	EPSD	ICGC;COSMIC	9.140	Down-regulation
AGC_SGK_SGK1_ST	Q6R327	RICTOR	O00141	SGK1	S1035	S1031C	1031	Missense	distal	-4	no	12.473	11.980	EPSD	ICGC;COSMIC;GDSC;CCLE	9.140	Down-regulation
AGC_SGK_SGK1_ST	Q6R327	RICTOR	O00141	SGK1	S1121	P1115S	1115	Missense	distal	-6	no	9.482	9.750	EPSD	ICGC	9.140	Up-regulation
AGC_SGK_SGK1_ST	Q6R327	RICTOR	O00141	SGK1	S1138	H1143Y	1143	Missense	distal	5	no	12.757	12.742	EPSD	ICGC	9.140	Down-regulation
AGC_SGK_SGK1_ST	Q6R327	RICTOR	O00141	SGK1	S1162	G1165E	1165	Missense	distal	3	no	10.736	10.718	EPSD	ICGC	9.140	Down-regulation
AGC_SGK_SGK1_ST	Q6R327	RICTOR	O00141	SGK1	S1219	R1216C	1216	Missense	distal	-3	no	14.980	6.918	EPSD	ICGC;COSMIC	9.140	Loss
AGC_SGK_SGK1_ST	Q6R327	RICTOR	O00141	SGK1	S1227	M1232V	1232	Missense	distal	5	no	11.248	11.217	EPSD	ICGC;COSMIC	9.140	Down-regulation
AGC_SGK_SGK1_ST	Q6R327	RICTOR	O00141	SGK1	S1227	S1230T	1230	Missense	distal	3	no	11.248	11.072	EPSD	ICGC	9.140	Down-regulation
AGC_SGK_SGK1_ST	Q6R327	RICTOR	O00141	SGK1	S1353	S1348C	1348	Missense	distal	-5	no	9.383	8.366	EPSD	ICGC;COSMIC	9.140	Loss
AGC_SGK_SGK1_ST	Q6R327	RICTOR	O00141	SGK1	S1353	S1353Y	1353	Missense	central	0	yes	9.383	0.000	EPSD	ICGC	9.140	Loss
AGC_SGK_SGK1_ST	Q6R327	RICTOR	O00141	SGK1	S1378	T1376A	1376	Missense	proximal	-2	no	10.137	10.304	EPSD	ICGC;COSMIC	9.140	Up-regulation
AGC_SGK_SGK1_ST	Q6R327	RICTOR	O00141	SGK1	S1378	S1373F	1373	Missense	distal	-5	no	10.137	7.380	EPSD	ICGC;COSMIC	9.140	Loss
AGC_SGK_SGK1_ST	P45985	MAP2K4	O00141	SGK1	S292	G294E	294	Missense	proximal	2	no	10.208	9.969	EPSD	ICGC;COSMIC	9.140	Down-regulation
AGC_SGK_SGK1_ST	O14920	IKBKB	O00141	SGK1	T23	R20C	20	Missense	distal	-3	no	11.541	3.479	EPSD	ICGC;COSMIC	9.140	Loss
AGC_SGK_SGK1_ST	O14920	IKBKB	O00141	SGK1	T23	N28I	28	Missense	distal	5	no	11.541	11.482	EPSD	ICGC;COSMIC	9.140	Down-regulation
AGC_SGK_SGK1_ST	P42858	HTT	O00141	SGK1	S262	R268W	268	Missense	distal	6	no	13.000	12.738	EPSD	ICGC;COSMIC	9.140	Down-regulation
AGC_SGK_SGK1_ST	P42858	HTT	O00141	SGK1	S262	R268Q	268	Missense	distal	6	no	13.000	12.921	EPSD	ICGC;COSMIC;CCLE	9.140	Down-regulation
AGC_SGK_SGK1_ST	P42858	HTT	O00141	SGK1	S262	S262I	262	Missense	central	0	yes	13.000	0.000	EPSD	ICGC	9.140	Loss
AGC_SGK_SGK1_ST	P42858	HTT	O00141	SGK1	S417	I420V	420	Missense	distal	3	no	10.943	10.807	EPSD	ICGC;COSMIC	9.140	Down-regulation
AGC_SGK_SGK1_ST	P42858	HTT	O00141	SGK1	S417	G412C	412	Missense	distal	-5	no	10.943	10.041	EPSD	ICGC;COSMIC	9.140	Down-regulation
AGC_SGK_SGK1_ST	P42858	HTT	O00141	SGK1	S419	I420V	420	Missense	proximal	1	no	21.602	21.624	PhosphoSitePlus	ICGC;COSMIC	9.140	Up-regulation
AGC_SGK_SGK1_ST	P42858	HTT	O00141	SGK1	S419	G412C	412	Missense	distal	-7	no	21.602	21.127	PhosphoSitePlus	ICGC;COSMIC	9.140	Down-regulation
AGC_SGK_SGK1_ST	P42858	HTT	O00141	SGK1	S621	E615G	615	Missense	distal	-6	no	9.218	9.200	EPSD	ICGC;COSMIC	9.140	Down-regulation
AGC_SGK_SGK1_ST	P42858	HTT	O00141	SGK1	S640	S634G	634	Missense	distal	-6	no	13.413	13.206	EPSD	ICGC;COSMIC	9.140	Down-regulation
AGC_SGK_SGK1_ST	P42858	HTT	O00141	SGK1	S640	P639S	639	Missense	proximal	-1	no	13.413	13.606	EPSD	ICGC;COSMIC	9.140	Up-regulation
AGC_SGK_SGK1_ST	P42858	HTT	O00141	SGK1	S642	P639S	639	Missense	distal	-3	no	4.768	9.959	EPSD	ICGC;COSMIC	9.140	Gain
AGC_SGK_SGK1_ST	P42858	HTT	O00141	SGK1	S689	F692L	692	Missense	distal	3	no	11.950	12.369	EPSD	ICGC	9.140	Up-regulation
AGC_SGK_SGK1_ST	P42858	HTT	O00141	SGK1	S689	A690S	690	Missense	proximal	1	no	11.950	11.994	EPSD	ICGC;COSMIC	9.140	Up-regulation
AGC_SGK_SGK1_ST	P42858	HTT	O00141	SGK1	T898	G893R	893	Missense	distal	-5	no	6.413	11.773	EPSD	ICGC;COSMIC	9.140	Gain
AGC_SGK_SGK1_ST	P42858	HTT	O00141	SGK1	S1111	W1109C	1109	Missense	proximal	-2	no	12.659	13.188	EPSD	ICGC;COSMIC	9.140	Up-regulation
AGC_SGK_SGK1_ST	P42858	HTT	O00141	SGK1	S1111	L1105M	1105	Missense	distal	-6	no	12.659	12.641	EPSD	ICGC;COSMIC	9.140	Down-regulation
AGC_SGK_SGK1_ST	P42858	HTT	O00141	SGK1	S1111	P1117Q	1117	Missense	distal	6	no	12.659	12.724	EPSD	ICGC;COSMIC	9.140	Up-regulation
AGC_SGK_SGK1_ST	P42858	HTT	O00141	SGK1	S1259	T1253M	1253	Missense	distal	-6	no	11.036	10.918	EPSD	ICGC;COSMIC	9.140	Down-regulation
AGC_SGK_SGK1_ST	P42858	HTT	O00141	SGK1	S1259	L1256F	1256	Missense	distal	-3	no	11.036	6.262	EPSD	ICGC	9.140	Loss
AGC_SGK_SGK1_ST	P42858	HTT	O00141	SGK1	S1259	Q1257R	1257	Missense	proximal	-2	no	11.036	11.490	EPSD	ICGC;COSMIC	9.140	Up-regulation
AGC_SGK_SGK1_ST	P42858	HTT	O00141	SGK1	S1349	G1346V	1346	Missense	distal	-3	no	13.169	8.005	EPSD	ICGC	9.140	Loss
AGC_SGK_SGK1_ST	P42858	HTT	O00141	SGK1	S1865	P1858L	1858	Missense	distal	-7	no	10.133	9.888	EPSD	ICGC;COSMIC	9.140	Down-regulation
AGC_SGK_SGK1_ST	P42858	HTT	O00141	SGK1	T2066	S2072I	2072	Missense	distal	6	no	13.982	13.727	EPSD	ICGC	9.140	Down-regulation
AGC_SGK_SGK1_ST	P42858	HTT	O00141	SGK1	T2455	R2461H	2461	Missense	distal	6	no	12.258	12.225	EPSD	ICGC;COSMIC;CCLE	9.140	Down-regulation
AGC_SGK_SGK1_ST	P42858	HTT	O00141	SGK1	S2812	A2818S	2818	Missense	distal	6	no	9.523	9.529	EPSD	ICGC;COSMIC	9.140	Up-regulation
AGC_SGK_SGK1_ST	P42858	HTT	O00141	SGK1	S2812	A2818T	2818	Missense	distal	6	no	9.523	9.464	EPSD	ICGC;COSMIC	9.140	Down-regulation
AGC_SGK_SGK1_ST	P42858	HTT	O00141	SGK1	S2812	D2808N	2808	Missense	distal	-4	no	9.523	9.696	EPSD	ICGC;COSMIC	9.140	Up-regulation
AGC_SGK_SGK1_ST	Q969H0	FBXW7	O00141	SGK1	S18	R20I	20	Missense	proximal	2	no	11.099	11.227	EPSD	ICGC;COSMIC	9.140	Up-regulation
AGC_SGK_SGK1_ST	Q969H0	FBXW7	O00141	SGK1	S18	R12I	12	Missense	distal	-6	no	11.099	10.775	EPSD	ICGC;COSMIC	9.140	Down-regulation
AGC_SGK_SGK1_ST	Q969H0	FBXW7	O00141	SGK1	S18	P23S	23	Missense	distal	5	no	11.099	11.164	EPSD	ICGC;COSMIC	9.140	Up-regulation
AGC_SGK_SGK1_ST	Q969H0	FBXW7	O00141	SGK1	S227	I225M	225	Missense	proximal	-2	no	18.838	18.858	PhosphoSitePlus	ICGC	9.140	Up-regulation
AGC_SGK_SGK1_ST	Q969H0	FBXW7	O00141	SGK1	S227	R223S	223	Missense	distal	-4	no	18.838	19.144	PhosphoSitePlus	ICGC	9.140	Up-regulation
AGC_SGK_SGK1_ST	Q969H0	FBXW7	O00141	SGK1	S227	T226I	226	Missense	proximal	-1	no	18.838	18.697	PhosphoSitePlus	ICGC;GDSC;CCLE	9.140	Down-regulation
AGC_SGK_SGK1_ST	Q969H0	FBXW7	O00141	SGK1	S227	R224Q	224	Missense	distal	-3	no	18.838	8.176	PhosphoSitePlus	ICGC;COSMIC	9.140	Loss
AGC_SGK_SGK1_ST	Q969H0	FBXW7	O00141	SGK1	T692	E693K	693	Missense	proximal	1	no	13.642	13.474	EPSD	ICGC;COSMIC	9.140	Down-regulation
AGC_SGK_SGK1_ST	Q969H0	FBXW7	O00141	SGK1	T692	G687E	687	Missense	distal	-5	no	13.642	10.929	EPSD	ICGC;COSMIC	9.140	Down-regulation
AGC_SGK_SGK1_ST	P25963	NFKBIA	O00141	SGK1	S32	R29S	29	Missense	distal	-3	no	14.940	8.034	PhosphoSitePlus	ICGC	9.140	Loss
AGC_SGK_SGK1_ST	P25963	NFKBIA	O00141	SGK1	S32	D31G	31	Missense	proximal	-1	no	14.940	14.891	PhosphoSitePlus	ICGC;COSMIC	9.140	Down-regulation
AGC_SGK_SGK1_ST	P25963	NFKBIA	O00141	SGK1	S32	K38T	38	Missense	distal	6	no	14.940	14.788	PhosphoSitePlus	ICGC	9.140	Down-regulation
TK_Jak_JAK1_Y	Q9NZQ7	CD274	P23458	JAK1	Y112	M115I	115	Missense	distal	3	no	9.028	9.288	PhosphoSitePlus	ICGC	8.575	Up-regulation
TK_Jak_JAK1_Y	Q9NZQ7	CD274	P23458	JAK1	Y112	G110V	110	Missense	proximal	-2	no	9.028	9.057	PhosphoSitePlus	ICGC;COSMIC	8.575	Up-regulation
TK_Jak_JAK1_Y	Q9NZQ7	CD274	P23458	JAK1	Y112	D108Y	108	Missense	distal	-4	no	9.028	9.033	PhosphoSitePlus	ICGC;COSMIC	8.575	Up-regulation
TK_Jak_JAK1_Y	Q9NZQ7	CD274	P23458	JAK1	Y112	V111A	111	Missense	proximal	-1	no	9.028	10.217	PhosphoSitePlus	ICGC;COSMIC	8.575	Up-regulation
TK_Jak_JAK1_Y	Q9NZQ7	CD274	P23458	JAK1	Y118	M115I	115	Missense	distal	-3	no	9.892	8.122	EPSD	ICGC	8.575	Loss
TK_Jak_JAK1_Y	Q9NZQ7	CD274	P23458	JAK1	Y118	V111A	111	Missense	distal	-7	no	9.892	9.504	EPSD	ICGC;COSMIC	8.575	Down-regulation
TK_Jak_JAK1_Y	Q99683	MAP3K5	P23458	JAK1	Y574	T567I	567	Missense	distal	-7	no	8.938	8.910	EPSD	ICGC;COSMIC	8.575	Down-regulation
TK_Jak_JAK1_Y	Q99683	MAP3K5	P23458	JAK1	Y718	P721H	721	Missense	distal	3	no	13.321	12.805	PhosphoSitePlus	ICGC	8.575	Down-regulation
TK_Jak_JAK1_Y	Q99683	MAP3K5	P23458	JAK1	Y718	S716R	716	Missense	proximal	-2	no	13.321	13.317	PhosphoSitePlus	ICGC	8.575	Down-regulation
TK_Jak_JAK1_Y	Q99683	MAP3K5	P23458	JAK1	Y718	S719Y	719	Missense	proximal	1	no	13.321	13.298	PhosphoSitePlus	ICGC;COSMIC	8.575	Down-regulation
TK_Jak_JAK1_Y	P42224	STAT1	P23458	JAK1	Y701	T704N	704	Missense	distal	3	no	19.205	18.861	PhosphoSitePlus	ICGC;COSMIC	8.575	Down-regulation
TK_Jak_JAK1_Y	P42224	STAT1	P23458	JAK1	Y701	K703E	703	Missense	proximal	2	no	19.205	19.265	PhosphoSitePlus	ICGC	8.575	Up-regulation
Atypical_TAF1_TAF1_ST	Q15545	TAF7	P21675	TAF1	S229	T236N	236	Missense	distal	7	no	3.327	3.313	EPSD	ICGC	2.466	Down-regulation
Atypical_TAF1_TAF1_ST	Q15545	TAF7	P21675	TAF1	T249	E242K	242	Missense	distal	-7	no	2.218	2.972	EPSD	ICGC;COSMIC	2.466	Gain
Atypical_TAF1_TAF1_ST	Q15545	TAF7	P21675	TAF1	S264	D259V	259	Missense	distal	-5	no	7.120	7.082	PhosphoSitePlus	ICGC;COSMIC	2.466	Down-regulation
Atypical_TAF1_TAF1_ST	Q15545	TAF7	P21675	TAF1	S264	Q269L	269	Missense	distal	5	no	7.120	7.285	PhosphoSitePlus	ICGC;COSMIC	2.466	Up-regulation
Atypical_TAF1_TAF1_ST	Q15545	TAF7	P21675	TAF1	S264	H268Q	268	Missense	distal	4	no	7.120	7.179	PhosphoSitePlus	ICGC	2.466	Up-regulation
Atypical_TAF1_TAF1_ST	P04637	TP53	P21675	TAF1	S46	D48G	48	Missense	proximal	2	no	3.420	1.882	EPSD	ICGC;COSMIC	2.466	Loss
Atypical_TAF1_TAF1_ST	P04637	TP53	P21675	TAF1	S46	Q52K	52	Missense	distal	6	no	3.420	3.640	EPSD	ICGC	2.466	Up-regulation
Atypical_TAF1_TAF1_ST	P04637	TP53	P21675	TAF1	T55	D48G	48	Missense	distal	-7	no	6.462	6.447	PhosphoSitePlus	ICGC;COSMIC	2.466	Down-regulation
Atypical_TAF1_TAF1_ST	P04637	TP53	P21675	TAF1	T55	Q52K	52	Missense	distal	-3	no	6.462	6.303	PhosphoSitePlus	ICGC	2.466	Down-regulation
Atypical_TAF1_TAF1_ST	P04637	TP53	P21675	TAF1	T55	E62K	62	Missense	distal	7	no	6.462	6.435	PhosphoSitePlus	ICGC;COSMIC	2.466	Down-regulation
Atypical_TAF1_TAF1_ST	P04637	TP53	P21675	TAF1	S183	C182W	182	Missense	proximal	-1	no	3.336	3.334	EPSD	ICGC;COSMIC	2.466	Down-regulation
Atypical_TAF1_TAF1_ST	P04637	TP53	P21675	TAF1	S183	H178D	178	Missense	distal	-5	no	3.336	3.343	EPSD	ICGC;COSMIC;CCLE	2.466	Up-regulation
Atypical_TAF1_TAF1_ST	P04637	TP53	P21675	TAF1	S183	D184H	184	Missense	proximal	1	no	3.336	2.061	EPSD	ICGC;COSMIC	2.466	Loss
Atypical_TAF1_TAF1_ST	P04637	TP53	P21675	TAF1	S183	A189T	189	Missense	distal	6	no	3.336	2.904	EPSD	ICGC;COSMIC	2.466	Down-regulation
Atypical_TAF1_TAF1_ST	P04637	TP53	P21675	TAF1	S183	P190T	190	Missense	distal	7	no	3.336	3.326	EPSD	ICGC;COSMIC	2.466	Down-regulation
Atypical_TAF1_TAF1_ST	P04637	TP53	P21675	TAF1	S183	A189D	189	Missense	distal	6	no	3.336	4.427	EPSD	ICGC;COSMIC	2.466	Up-regulation
Atypical_TAF1_TAF1_ST	P04637	TP53	P21675	TAF1	S183	E180D	180	Missense	distal	-3	no	3.336	3.910	EPSD	ICGC;COSMIC	2.466	Up-regulation
Atypical_TAF1_TAF1_ST	P04637	TP53	P21675	TAF1	S183	C176G	176	Missense	distal	-7	no	3.336	3.328	EPSD	ICGC;COSMIC	2.466	Down-regulation
Atypical_TAF1_TAF1_ST	P04637	TP53	P21675	TAF1	S313	T312I	312	Missense	proximal	-1	no	3.173	3.180	EPSD	ICGC;COSMIC	2.466	Up-regulation
Atypical_TAF1_TAF1_ST	P04637	TP53	P21675	TAF1	T387	F385L	385	Missense	proximal	-2	no	2.456	2.592	EPSD	ICGC;COSMIC	2.466	Gain
Atypical_TAF1_TAF1_ST	P04637	TP53	P21675	TAF1	S392	F385L	385	Missense	distal	-7	no	2.497	2.677	EPSD	ICGC;COSMIC	2.466	Up-regulation
TK_Abl_ABL1_Y	P37840	SNCA	P00519	ABL1	Y125	P120T	120	Missense	distal	-5	no	11.633	12.174	EPSD;PhosphoSitePlus	ICGC	7.039	Up-regulation
TK_Abl_ABL1_Y	P37840	SNCA	P00519	ABL1	Y136	Q134K	134	Missense	proximal	-2	no	8.117	6.875	EPSD	ICGC;COSMIC	7.039	Loss
TK_Abl_ABL1_Y	P46937	YAP1	P00519	ABL1	Y407	L402P	402	Missense	distal	-5	no	7.992	9.391	PhosphoSitePlus	ICGC;COSMIC	7.039	Up-regulation
TK_Abl_ABL1_Y	P46937	YAP1	P00519	ABL1	Y407	V409F	409	Missense	proximal	2	no	7.992	8.297	PhosphoSitePlus	ICGC	7.039	Up-regulation
TK_Abl_ABL1_Y	Q9UL17	TBX21	P00519	ABL1	Y220	R218C	218	Missense	proximal	-2	no	10.447	10.262	EPSD;PhosphoSitePlus	ICGC;COSMIC	7.039	Down-regulation
TK_Abl_ABL1_Y	Q9UL17	TBX21	P00519	ABL1	Y220	V221F	221	Missense	proximal	1	no	10.447	7.848	EPSD;PhosphoSitePlus	ICGC;COSMIC	7.039	Down-regulation
TK_Abl_ABL1_Y	Q9UL17	TBX21	P00519	ABL1	Y220	M214I	214	Missense	distal	-6	no	10.447	10.539	EPSD;PhosphoSitePlus	ICGC;COSMIC	7.039	Up-regulation
TK_Abl_ABL1_Y	P04040	CAT	P00519	ABL1	Y231	G227V	227	Missense	distal	-4	no	9.490	9.186	PhosphoSitePlus;EPSD	ICGC	7.039	Down-regulation
TK_Abl_ABL1_Y	P04040	CAT	P00519	ABL1	Y231	E228D	228	Missense	distal	-3	no	9.490	8.841	PhosphoSitePlus;EPSD	ICGC	7.039	Down-regulation
TK_Abl_ABL1_Y	P04040	CAT	P00519	ABL1	Y386	Q387H	387	Missense	proximal	1	no	7.047	5.660	EPSD;PhosphoSitePlus	ICGC;COSMIC	7.039	Loss
TK_Abl_ABL1_Y	P04040	CAT	P00519	ABL1	Y386	G390C	390	Missense	distal	4	no	7.047	7.233	EPSD;PhosphoSitePlus	ICGC	7.039	Up-regulation
TK_Abl_ABL1_Y	P04040	CAT	P00519	ABL1	Y386	D389N	389	Missense	distal	3	no	7.047	7.992	EPSD;PhosphoSitePlus	ICGC	7.039	Up-regulation
TK_Abl_ABL1_Y	Q15746	MYLK	P00519	ABL1	Y231	D227E	227	Missense	distal	-4	no	7.896	9.182	EPSD;PhosphoSitePlus	ICGC	7.039	Up-regulation
TK_Abl_ABL1_Y	Q15746	MYLK	P00519	ABL1	Y556	A557T	557	Missense	proximal	1	no	9.861	8.594	EPSD;PhosphoSitePlus	ICGC;COSMIC	7.039	Down-regulation
TK_Abl_ABL1_Y	Q15746	MYLK	P00519	ABL1	Y556	Q552P	552	Missense	distal	-4	no	9.861	10.061	EPSD;PhosphoSitePlus	ICGC;COSMIC	7.039	Up-regulation
TK_Abl_ABL1_Y	Q15746	MYLK	P00519	ABL1	Y611	V615M	615	Missense	distal	4	no	9.079	8.903	EPSD;PhosphoSitePlus	ICGC	7.039	Down-regulation
TK_Abl_ABL1_Y	Q15746	MYLK	P00519	ABL1	Y611	A616T	616	Missense	distal	5	no	9.079	8.688	EPSD;PhosphoSitePlus	ICGC;COSMIC	7.039	Down-regulation
TK_Abl_ABL1_Y	Q15746	MYLK	P00519	ABL1	Y792	N798S	798	Missense	distal	6	no	8.354	8.061	EPSD;PhosphoSitePlus	ICGC;COSMIC	7.039	Down-regulation
TK_Abl_ABL1_Y	Q15746	MYLK	P00519	ABL1	Y792	R799Q	799	Missense	distal	7	no	8.354	8.382	EPSD;PhosphoSitePlus	ICGC	7.039	Up-regulation
TK_Abl_ABL1_Y	Q15746	MYLK	P00519	ABL1	Y792	R799W	799	Missense	distal	7	no	8.354	8.325	EPSD;PhosphoSitePlus	ICGC	7.039	Down-regulation
TK_Abl_ABL1_Y	Q15746	MYLK	P00519	ABL1	Y1449	T1453K	1453	Missense	distal	4	no	7.716	7.521	PhosphoSitePlus;EPSD	ICGC;COSMIC	7.039	Down-regulation
TK_Abl_ABL1_Y	Q15746	MYLK	P00519	ABL1	Y1575	H1577Q	1577	Missense	proximal	2	no	8.886	9.174	EPSD;PhosphoSitePlus	ICGC	7.039	Up-regulation
TK_Abl_ABL1_Y	P00519	ABL1	P00519	ABL1	Y139	G144W	144	Missense	distal	5	no	6.852	7.131	EPSD	ICGC	7.039	Gain
TK_Abl_ABL1_Y	P00519	ABL1	P00519	ABL1	Y185	E189G	189	Missense	distal	4	no	7.607	7.223	EPSD	ICGC;COSMIC	7.039	Down-regulation
TK_Abl_ABL1_Y	P00519	ABL1	P00519	ABL1	Y185	V186I	186	Missense	proximal	1	no	7.607	6.821	EPSD	ICGC;COSMIC	7.039	Loss
TK_Abl_ABL1_Y	P00519	ABL1	P00519	ABL1	Y226	Y232C	232	Missense	distal	6	no	7.319	6.771	EPSD	ICGC;COSMIC	7.039	Loss
TK_Abl_ABL1_Y	P00519	ABL1	P00519	ABL1	Y226	D233N	233	Missense	distal	7	no	7.319	7.346	EPSD	ICGC;COSMIC	7.039	Up-regulation
TK_Abl_ABL1_Y	P00519	ABL1	P00519	ABL1	Y226	D233Y	233	Missense	distal	7	no	7.319	7.293	EPSD	ICGC	7.039	Down-regulation
TK_Abl_ABL1_Y	O15350	TP73	P00519	ABL1	Y99	S104F	104	Missense	distal	5	no	11.076	11.793	PhosphoSitePlus	ICGC;COSMIC	7.039	Up-regulation
TK_Abl_ABL1_Y	O15350	TP73	P00519	ABL1	Y99	S103I	103	Missense	distal	4	no	11.076	11.260	PhosphoSitePlus	ICGC	7.039	Up-regulation
TK_Abl_ABL1_Y	Q03135	CAV1	P00519	ABL1	Y14	V7L	7	Missense	distal	-7	no	13.796	13.309	PhosphoSitePlus	ICGC	7.039	Down-regulation
TK_Abl_ABL1_Y	Q03135	CAV1	P00519	ABL1	Y14	E10D	10	Missense	distal	-4	no	13.796	12.510	PhosphoSitePlus	ICGC	7.039	Down-regulation
TK_Abl_ABL1_Y	Q03135	CAV1	P00519	ABL1	Y14	V16I	16	Missense	proximal	2	no	13.796	14.772	PhosphoSitePlus	ICGC;COSMIC	7.039	Up-regulation
TK_Abl_ABL1_Y	Q03135	CAV1	P00519	ABL1	Y14	R19L	19	Missense	distal	5	no	13.796	14.199	PhosphoSitePlus	ICGC;COSMIC	7.039	Up-regulation
TK_Abl_ABL1_Y	Q03135	CAV1	P00519	ABL1	Y25	R19L	19	Missense	distal	-6	no	7.852	7.609	EPSD	ICGC;COSMIC	7.039	Down-regulation
TK_Abl_ABL1_Y	Q06609	RAD51	P00519	ABL1	Y315	D316N	316	Missense	proximal	1	no	14.055	13.755	PhosphoSitePlus;EPSD	ICGC;COSMIC	7.039	Down-regulation
TK_Abl_ABL1_Y	P55317	FOXA1	P00519	ABL1	Y459	A454T	454	Missense	distal	-5	no	7.548	7.938	EPSD	ICGC;COSMIC	7.039	Up-regulation
TK_Abl_ABL1_Y	P55317	FOXA1	P00519	ABL1	Y459	Q461K	461	Missense	proximal	2	no	7.548	7.048	EPSD	ICGC;COSMIC	7.039	Down-regulation
TK_Abl_ABL1_Y	P55317	FOXA1	P00519	ABL1	Y460	A454T	454	Missense	distal	-6	no	8.009	7.997	EPSD	ICGC;COSMIC	7.039	Down-regulation
TK_Abl_ABL1_Y	P55317	FOXA1	P00519	ABL1	Y460	Q461K	461	Missense	proximal	1	no	8.009	7.705	EPSD	ICGC;COSMIC	7.039	Down-regulation
TK_Abl_ABL1_Y	P55317	FOXA1	P00519	ABL1	Y464	V468F	468	Missense	distal	4	no	11.533	11.253	PhosphoSitePlus;EPSD	ICGC;COSMIC	7.039	Down-regulation
TK_Abl_ABL1_Y	P55317	FOXA1	P00519	ABL1	Y464	Q461K	461	Missense	distal	-3	no	11.533	11.229	PhosphoSitePlus;EPSD	ICGC;COSMIC	7.039	Down-regulation
TK_Abl_ABL1_Y	P03372	ESR1	P00519	ABL1	Y52	V51M	51	Missense	proximal	-1	no	9.828	8.917	PhosphoSitePlus;EPSD	ICGC	7.039	Down-regulation
TK_Abl_ABL1_Y	P03372	ESR1	P00519	ABL1	Y52	D45E	45	Missense	distal	-7	no	9.828	9.555	PhosphoSitePlus;EPSD	ICGC;COSMIC	7.039	Down-regulation
TK_Abl_ABL1_Y	P03372	ESR1	P00519	ABL1	Y52	A50S	50	Missense	proximal	-2	no	9.828	10.479	PhosphoSitePlus;EPSD	ICGC	7.039	Up-regulation
TK_Abl_ABL1_Y	P03372	ESR1	P00519	ABL1	Y219	P222S	222	Missense	distal	3	no	9.788	6.653	EPSD;PhosphoSitePlus	ICGC;COSMIC	7.039	Loss
TK_Abl_ABL1_Y	P03372	ESR1	P00519	ABL1	Y219	T224N	224	Missense	distal	5	no	9.788	9.592	EPSD;PhosphoSitePlus	ICGC;COSMIC	7.039	Down-regulation
TK_Abl_ABL1_Y	P03372	ESR1	P00519	ABL1	Y219	Q226H	226	Missense	distal	7	no	9.788	9.732	EPSD;PhosphoSitePlus	ICGC;COSMIC	7.039	Down-regulation
TK_Abl_ABL1_Y	P03372	ESR1	P00519	ABL1	Y219	M220I	220	Missense	proximal	1	no	9.788	9.095	EPSD;PhosphoSitePlus	ICGC	7.039	Down-regulation
TK_Abl_ABL1_Y	P03372	ESR1	P00519	ABL1	Y328	E330A	330	Missense	proximal	2	no	7.495	8.215	EPSD	ICGC	7.039	Up-regulation
TK_Abl_ABL1_Y	P03372	ESR1	P00519	ABL1	Y328	P324T	324	Missense	distal	-4	no	7.495	6.858	EPSD	ICGC	7.039	Loss
TK_Abl_ABL1_Y	P03372	ESR1	P00519	ABL1	Y328	A322S	322	Missense	distal	-6	no	7.495	7.602	EPSD	ICGC	7.039	Up-regulation
TK_Abl_ABL1_Y	P03372	ESR1	P00519	ABL1	Y328	E330K	330	Missense	proximal	2	no	7.495	7.512	EPSD	ICGC;COSMIC	7.039	Up-regulation
TK_Abl_ABL1_Y	Q13535	ATR	P00519	ABL1	Y291	D286Y	286	Missense	distal	-5	no	7.178	6.498	EPSD;PhosphoSitePlus	ICGC;COSMIC	7.039	Loss
TK_Abl_ABL1_Y	Q13535	ATR	P00519	ABL1	Y291	D286E	286	Missense	distal	-5	no	7.178	7.238	EPSD;PhosphoSitePlus	ICGC	7.039	Up-regulation
TK_Abl_ABL1_Y	Q13535	ATR	P00519	ABL1	Y291	Q287K	287	Missense	distal	-4	no	7.178	5.998	EPSD;PhosphoSitePlus	ICGC	7.039	Loss
TK_Abl_ABL1_Y	P11274	BCR	P00519	ABL1	Y283	Y276H	276	Missense	distal	-7	no	8.285	8.327	EPSD	ICGC;COSMIC	7.039	Up-regulation
TK_Abl_ABL1_Y	P11274	BCR	P00519	ABL1	Y283	G285W	285	Missense	proximal	2	no	8.285	6.861	EPSD	ICGC;COSMIC	7.039	Loss
TK_Abl_ABL1_Y	P11274	BCR	P00519	ABL1	Y360	P355T	355	Missense	distal	-5	no	9.495	10.036	EPSD	ICGC;COSMIC	7.039	Up-regulation
TK_Abl_ABL1_Y	P11274	BCR	P00519	ABL1	Y360	S367G	367	Missense	distal	7	no	9.495	9.481	EPSD	ICGC;COSMIC	7.039	Down-regulation
TK_Abl_ABL1_Y	P11274	BCR	P00519	ABL1	Y360	R364L	364	Missense	distal	4	no	9.495	9.095	EPSD	ICGC;COSMIC	7.039	Down-regulation
TK_Abl_ABL1_Y	P11274	BCR	P00519	ABL1	Y360	R361S	361	Missense	proximal	1	no	9.495	9.786	EPSD	ICGC;COSMIC	7.039	Up-regulation
TK_Abl_ABL1_Y	P11274	BCR	P00519	ABL1	Y455	R448L	448	Missense	distal	-7	no	8.418	8.181	EPSD	ICGC	7.039	Down-regulation
TK_Abl_ABL1_Y	P19174	PLCG1	P00519	ABL1	Y162	R166L	166	Missense	distal	4	no	7.137	6.737	EPSD	ICGC	7.039	Loss
TK_Abl_ABL1_Y	P19174	PLCG1	P00519	ABL1	Y162	R158L	158	Missense	distal	-4	no	7.137	5.904	EPSD	ICGC	7.039	Loss
TK_Abl_ABL1_Y	P19174	PLCG1	P00519	ABL1	Y210	G206E	206	Missense	distal	-4	no	9.726	10.773	EPSD	ICGC	7.039	Up-regulation
TK_Abl_ABL1_Y	P19174	PLCG1	P00519	ABL1	Y210	G206K	206	Missense	distal	-4	no	9.726	8.107	EPSD	ICGC	7.039	Down-regulation
TK_Abl_ABL1_Y	P19174	PLCG1	P00519	ABL1	Y210	G206R	206	Missense	distal	-4	no	9.726	9.529	EPSD	ICGC	7.039	Down-regulation
TK_Abl_ABL1_Y	P19174	PLCG1	P00519	ABL1	Y472	K465N	465	Missense	distal	-7	no	10.069	10.653	EPSD	ICGC	7.039	Up-regulation
TK_Abl_ABL1_Y	P19174	PLCG1	P00519	ABL1	Y771	R778H	778	Missense	distal	7	no	9.737	9.708	EPSD;PhosphoSitePlus	ICGC;COSMIC	7.039	Down-regulation
TK_Abl_ABL1_Y	P19174	PLCG1	P00519	ABL1	Y771	G772E	772	Missense	proximal	1	no	9.737	10.177	EPSD;PhosphoSitePlus	ICGC	7.039	Up-regulation
TK_Abl_ABL1_Y	P19174	PLCG1	P00519	ABL1	Y771	A767V	767	Missense	distal	-4	no	9.737	9.959	EPSD;PhosphoSitePlus	ICGC;COSMIC	7.039	Up-regulation
TK_Abl_ABL1_Y	P19174	PLCG1	P00519	ABL1	Y783	R778H	778	Missense	distal	-5	no	8.857	7.088	EPSD	ICGC;COSMIC	7.039	Down-regulation
TK_Abl_ABL1_Y	P19174	PLCG1	P00519	ABL1	Y977	G971C	971	Missense	distal	-6	no	7.677	7.684	EPSD	ICGC;COSMIC	7.039	Up-regulation
TK_Abl_ABL1_Y	P19174	PLCG1	P00519	ABL1	Y977	P984Q	984	Missense	distal	7	no	7.677	7.711	EPSD	ICGC;COSMIC	7.039	Up-regulation
TK_Abl_ABL1_Y	P19174	PLCG1	P00519	ABL1	Y1003	R1010S	1010	Missense	distal	7	no	7.294	7.280	PhosphoSitePlus;EPSD	ICGC;COSMIC	7.039	Down-regulation
TK_Abl_ABL1_Y	P08581	MET	P00519	ABL1	Y291	M294I	294	Missense	distal	3	no	7.451	6.941	EPSD	ICGC;COSMIC	7.039	Loss
TK_Abl_ABL1_Y	P08581	MET	P00519	ABL1	Y835	I834F	834	Missense	proximal	-1	no	8.252	6.006	EPSD	ICGC;COSMIC	7.039	Loss
TK_Abl_ABL1_Y	P08581	MET	P00519	ABL1	Y835	D832Y	832	Missense	distal	-3	no	8.252	8.279	EPSD	ICGC	7.039	Up-regulation
TK_Abl_ABL1_Y	P08581	MET	P00519	ABL1	Y835	V836I	836	Missense	proximal	1	no	8.252	7.466	EPSD	ICGC;COSMIC	7.039	Down-regulation
TK_Abl_ABL1_Y	P08581	MET	P00519	ABL1	Y1159	P1153L	1153	Missense	distal	-6	no	7.456	7.304	EPSD	ICGC;COSMIC	7.039	Down-regulation
TK_Abl_ABL1_Y	P08581	MET	P00519	ABL1	Y1159	H1162R	1162	Missense	distal	3	no	7.456	6.031	EPSD	ICGC	7.039	Loss
TK_Abl_ABL1_Y	P08581	MET	P00519	ABL1	Y1159	M1160I	1160	Missense	proximal	1	no	7.456	6.764	EPSD	ICGC;COSMIC	7.039	Loss
TK_Abl_ABL1_Y	P08581	MET	P00519	ABL1	Y1159	P1153Q	1153	Missense	distal	-6	no	7.456	7.484	EPSD	ICGC;COSMIC	7.039	Up-regulation
TK_Abl_ABL1_Y	P08581	MET	P00519	ABL1	Y1349	V1352L	1352	Missense	distal	3	no	7.534	6.878	EPSD;PhosphoSitePlus	ICGC;COSMIC	7.039	Loss
TK_Abl_ABL1_Y	P08581	MET	P00519	ABL1	Y1349	H1351Y	1351	Missense	proximal	2	no	7.534	7.298	EPSD;PhosphoSitePlus	ICGC;COSMIC	7.039	Down-regulation
TK_Abl_ABL1_Y	P08581	MET	P00519	ABL1	Y1349	Y1356C	1356	Missense	distal	7	no	7.534	7.503	EPSD;PhosphoSitePlus	ICGC;COSMIC	7.039	Down-regulation
TK_Abl_ABL1_Y	P08581	MET	P00519	ABL1	Y1356	H1351Y	1351	Missense	distal	-5	no	6.978	7.690	PhosphoSitePlus;EPSD	ICGC;COSMIC	7.039	Gain
TK_Abl_ABL1_Y	Q06187	BTK	P00519	ABL1	Y551	K558T	558	Missense	distal	7	no	8.504	8.528	EPSD	ICGC	7.039	Up-regulation
TK_Abl_ABL1_Y	Q6P1J9	CDC73	P00519	ABL1	Y315	G317V	317	Missense	proximal	2	no	7.368	6.957	PhosphoSitePlus;EPSD	ICGC	7.039	Loss
TK_Abl_ABL1_Y	Q6P1J9	CDC73	P00519	ABL1	Y315	Y315C	315	Missense	central	0	yes	7.368	0.000	PhosphoSitePlus;EPSD	ICGC;COSMIC	7.039	Loss
TK_Abl_ABL1_Y	Q6P1J9	CDC73	P00519	ABL1	Y315	H316Y	316	Missense	proximal	1	no	7.368	8.971	PhosphoSitePlus;EPSD	ICGC;COSMIC	7.039	Up-regulation
TK_Abl_ABL1_Y	Q6P1J9	CDC73	P00519	ABL1	Y315	T311S	311	Missense	distal	-4	no	7.368	7.767	PhosphoSitePlus;EPSD	ICGC;COSMIC	7.039	Up-regulation
TK_Abl_ABL1_Y	P00533	EGFR	P00519	ABL1	Y113	N115K	115	Missense	proximal	2	no	7.303	6.784	EPSD	ICGC;COSMIC	7.039	Loss
TK_Abl_ABL1_Y	P00533	EGFR	P00519	ABL1	Y113	Y117C	117	Missense	distal	4	no	7.303	7.411	EPSD	ICGC;COSMIC	7.039	Up-regulation
TK_Abl_ABL1_Y	P00533	EGFR	P00519	ABL1	Y998	S991R	991	Missense	distal	-7	no	7.230	7.198	EPSD	ICGC;COSMIC	7.039	Down-regulation
TK_Abl_ABL1_Y	P00533	EGFR	P00519	ABL1	Y1197	Y1197C	1197	Missense	central	0	yes	9.785	0.000	EPSD;PhosphoSitePlus	ICGC;COSMIC	7.039	Loss
TK_Abl_ABL1_Y	P00533	EGFR	P00519	ABL1	Y1197	L1198I	1198	Missense	proximal	1	no	9.785	10.809	EPSD;PhosphoSitePlus	ICGC;COSMIC	7.039	Up-regulation
TK_Abl_ABL1_Y	P53350	PLK1	P00519	ABL1	Y217	P220A	220	Missense	distal	3	no	9.779	5.676	PhosphoSitePlus;EPSD	ICGC;COSMIC	7.039	Loss
TK_Abl_ABL1_Y	P53350	PLK1	P00519	ABL1	Y217	E221K	221	Missense	distal	4	no	9.779	9.404	PhosphoSitePlus;EPSD	ICGC;COSMIC	7.039	Down-regulation
TK_Abl_ABL1_Y	Q13573	SNW1	P00519	ABL1	Y260	T261K	261	Missense	proximal	1	no	7.051	6.672	EPSD	ICGC	7.039	Loss
TK_Abl_ABL1_Y	Q13573	SNW1	P00519	ABL1	Y260	D265E	265	Missense	distal	5	no	7.051	6.694	EPSD	ICGC	7.039	Loss
TK_Abl_ABL1_Y	Q13573	SNW1	P00519	ABL1	Y260	R267C	267	Missense	distal	7	no	7.051	6.969	EPSD	ICGC;COSMIC	7.039	Loss
TK_Abl_ABL1_Y	Q13573	SNW1	P00519	ABL1	Y292	D295Y	295	Missense	distal	3	no	7.093	7.229	PhosphoSitePlus;EPSD	ICGC;COSMIC	7.039	Up-regulation
TK_Abl_ABL1_Y	P17676	CEBPB	P00519	ABL1	Y78	I73M	73	Missense	distal	-5	no	6.584	7.252	PhosphoSitePlus	ICGC	7.039	Gain
TK_Abl_ABL1_Y	P17676	CEBPB	P00519	ABL1	Y137	P134L	134	Missense	distal	-3	no	8.440	7.674	EPSD	ICGC	7.039	Down-regulation
TK_Abl_ABL1_Y	P17676	CEBPB	P00519	ABL1	Y137	A135T	135	Missense	proximal	-2	no	8.440	8.657	EPSD	ICGC;COSMIC	7.039	Up-regulation
TK_Abl_ABL1_Y	P17676	CEBPB	P00519	ABL1	Y137	L142P	142	Missense	distal	5	no	8.440	7.809	EPSD	ICGC;COSMIC	7.039	Down-regulation
TK_Abl_ABL1_Y	P01112	HRAS	P00519	ABL1	Y137	G138R	138	Missense	proximal	1	no	7.057	6.996	PhosphoSitePlus	ICGC	7.039	Loss
TK_Abl_ABL1_Y	O15151	MDM4	P00519	ABL1	Y99	D100G	100	Missense	proximal	1	no	7.822	6.950	EPSD;PhosphoSitePlus	ICGC;COSMIC	7.039	Loss
TK_Abl_ABL1_Y	P09619	PDGFRB	P00519	ABL1	Y579	S573R	573	Missense	distal	-6	no	7.429	7.500	EPSD	ICGC	7.039	Up-regulation
TK_Abl_ABL1_Y	P09619	PDGFRB	P00519	ABL1	Y579	H577N	577	Missense	proximal	-2	no	7.429	7.631	EPSD	ICGC	7.039	Up-regulation
TK_Abl_ABL1_Y	P09619	PDGFRB	P00519	ABL1	Y579	P584H	584	Missense	distal	5	no	7.429	7.724	EPSD	ICGC;COSMIC	7.039	Up-regulation
TK_Abl_ABL1_Y	P09619	PDGFRB	P00519	ABL1	Y581	H577N	577	Missense	distal	-4	no	8.600	9.566	EPSD	ICGC	7.039	Up-regulation
TK_Abl_ABL1_Y	P09619	PDGFRB	P00519	ABL1	Y581	P584H	584	Missense	distal	3	no	8.600	5.384	EPSD	ICGC;COSMIC	7.039	Loss
TK_Abl_ABL1_Y	P09619	PDGFRB	P00519	ABL1	Y716	P710Q	710	Missense	distal	-6	no	7.053	7.080	EPSD	ICGC	7.039	Up-regulation
TK_Abl_ABL1_Y	P09619	PDGFRB	P00519	ABL1	Y716	A719P	719	Missense	distal	3	no	7.053	11.155	EPSD	ICGC;COSMIC	7.039	Up-regulation
TK_Abl_ABL1_Y	P09619	PDGFRB	P00519	ABL1	Y716	E714K	714	Missense	proximal	-2	no	7.053	6.380	EPSD	ICGC;COSMIC	7.039	Loss
TK_Abl_ABL1_Y	P09619	PDGFRB	P00519	ABL1	Y771	A764E	764	Missense	distal	-7	no	8.867	8.758	EPSD	ICGC	7.039	Down-regulation
TK_Abl_ABL1_Y	P09619	PDGFRB	P00519	ABL1	Y934	H928R	928	Missense	distal	-6	no	8.950	9.122	EPSD;PhosphoSitePlus	ICGC;COSMIC	7.039	Up-regulation
TK_Abl_ABL1_Y	P09619	PDGFRB	P00519	ABL1	Y1021	D1018G	1018	Missense	distal	-3	no	7.377	7.142	EPSD	ICGC;COSMIC	7.039	Down-regulation
TK_Abl_ABL1_Y	P09619	PDGFRB	P00519	ABL1	Y1021	D1020N	1020	Missense	proximal	-1	no	7.377	7.049	EPSD	ICGC;COSMIC;CCLE	7.039	Down-regulation
TK_Abl_ABL1_Y	Q14247	CTTN	P00519	ABL1	Y104	G101V	101	Missense	distal	-3	no	6.946	7.086	EPSD	ICGC;COSMIC	7.039	Gain
TK_Abl_ABL1_Y	Q14247	CTTN	P00519	ABL1	Y154	G160S	160	Missense	distal	6	no	6.827	7.071	EPSD	ICGC;COSMIC	7.039	Gain
TK_Abl_ABL1_Y	Q14247	CTTN	P00519	ABL1	Y178	D177A	177	Missense	proximal	-1	no	6.685	7.115	EPSD	ICGC;COSMIC	7.039	Gain
TK_Abl_ABL1_Y	Q14247	CTTN	P00519	ABL1	Y302	G305V	305	Missense	distal	3	no	4.627	7.273	EPSD	ICGC	7.039	Gain
TK_Abl_ABL1_Y	Q14247	CTTN	P00519	ABL1	Y421	A424V	424	Missense	distal	3	no	5.043	7.225	EPSD	ICGC;COSMIC;GDSC	7.039	Gain
TK_Abl_ABL1_Y	Q14247	CTTN	P00519	ABL1	Y479	P480A	480	Missense	proximal	1	no	5.119	7.203	EPSD	ICGC;COSMIC	7.039	Gain
TK_Abl_ABL1_Y	Q14247	CTTN	P00519	ABL1	Y486	D483N	483	Missense	distal	-3	no	9.676	9.640	PhosphoSitePlus	ICGC;COSMIC	7.039	Down-regulation
TK_Abl_ABL1_Y	Q14247	CTTN	P00519	ABL1	Y486	D487N	487	Missense	proximal	1	no	9.676	9.376	PhosphoSitePlus	ICGC;COSMIC;GDSC	7.039	Down-regulation
TK_Abl_ABL1_Y	Q14247	CTTN	P00519	ABL1	Y486	P480A	480	Missense	distal	-6	no	9.676	9.587	PhosphoSitePlus	ICGC;COSMIC	7.039	Down-regulation
TK_Abl_ABL1_Y	Q14247	CTTN	P00519	ABL1	Y486	D492Y	492	Missense	distal	6	no	9.676	9.690	PhosphoSitePlus	ICGC;COSMIC	7.039	Up-regulation
TK_Abl_ABL1_Y	Q14247	CTTN	P00519	ABL1	Y486	D492H	492	Missense	distal	6	no	9.676	9.837	PhosphoSitePlus	ICGC;COSMIC	7.039	Up-regulation
TK_Abl_ABL1_Y	Q14247	CTTN	P00519	ABL1	Y486	P480S	480	Missense	distal	-6	no	9.676	9.695	PhosphoSitePlus	ICGC;COSMIC	7.039	Up-regulation
TK_Abl_ABL1_Y	Q14247	CTTN	P00519	ABL1	Y486	L493M	493	Missense	distal	7	no	9.676	9.705	PhosphoSitePlus	ICGC;COSMIC	7.039	Up-regulation
TK_Abl_ABL1_Y	Q14247	CTTN	P00519	ABL1	Y538	R531C	531	Missense	distal	-7	no	8.489	8.186	EPSD	ICGC	7.039	Down-regulation
TK_Abl_ABL1_Y	Q14247	CTTN	P00519	ABL1	Y538	G532V	532	Missense	distal	-6	no	8.489	8.549	EPSD	ICGC;COSMIC	7.039	Up-regulation
TK_Abl_ABL1_Y	Q14247	CTTN	P00519	ABL1	Y538	G532W	532	Missense	distal	-6	no	8.489	8.480	EPSD	ICGC;COSMIC	7.039	Down-regulation
TK_Abl_ABL1_Y	Q14247	CTTN	P00519	ABL1	Y538	C534S	534	Missense	distal	-4	no	8.489	9.165	EPSD	ICGC;COSMIC	7.039	Up-regulation
TK_Abl_ABL1_Y	Q14247	CTTN	P00519	ABL1	Y538	G536V	536	Missense	proximal	-2	no	8.489	8.614	EPSD	ICGC	7.039	Up-regulation
TK_Abl_ABL1_Y	Q14247	CTTN	P00519	ABL1	Y538	R531L	531	Missense	distal	-7	no	8.489	8.252	EPSD	ICGC	7.039	Down-regulation
TK_Abl_ABL1_Y	Q14247	CTTN	P00519	ABL1	Y538	R537Q	537	Missense	proximal	-1	no	8.489	9.038	EPSD	ICGC;COSMIC	7.039	Up-regulation
TK_Abl_ABL1_Y	Q14247	CTTN	P00519	ABL1	Y538	G532R	532	Missense	distal	-6	no	8.489	8.707	EPSD	ICGC;COSMIC	7.039	Up-regulation
TK_Abl_ABL1_Y	Q14247	CTTN	P00519	ABL1	Y538	K535N	535	Missense	distal	-3	no	8.489	8.831	EPSD	ICGC;COSMIC	7.039	Up-regulation
TK_Abl_ABL1_Y	Q14247	CTTN	P00519	ABL1	Y538	P542Q	542	Missense	distal	4	no	8.489	7.938	EPSD	ICGC;COSMIC	7.039	Down-regulation
TK_Abl_ABL1_Y	Q9H3D4	TP63	P00519	ABL1	Y149	S154F	154	Missense	distal	5	no	11.962	12.679	EPSD;PhosphoSitePlus	ICGC;COSMIC;GDSC;CCLE	7.039	Up-regulation
TK_Abl_ABL1_Y	Q9H3D4	TP63	P00519	ABL1	Y149	V143I	143	Missense	distal	-6	no	11.962	11.981	EPSD;PhosphoSitePlus	ICGC;COSMIC	7.039	Up-regulation
TK_Abl_ABL1_Y	Q9H3D4	TP63	P00519	ABL1	Y149	T144M	144	Missense	distal	-5	no	11.962	10.544	EPSD;PhosphoSitePlus	ICGC;COSMIC	7.039	Down-regulation
TK_Abl_ABL1_Y	Q9Y6Q9	NCOA3	P00519	ABL1	Y1357	Q1358E	1358	Missense	proximal	1	no	8.959	9.195	PhosphoSitePlus	ICGC;COSMIC	7.039	Up-regulation
TK_Abl_ABL1_Y	P46108	CRK	P00519	ABL1	Y221	T228I	228	Missense	distal	7	no	16.217	16.142	PhosphoSitePlus;EPSD	ICGC;COSMIC	7.039	Down-regulation
TK_Abl_ABL1_Y	P46108	CRK	P00519	ABL1	Y239	Y239F	239	Missense	central	0	yes	10.694	0.000	EPSD;PhosphoSitePlus	ICGC;COSMIC	7.039	Loss
TK_Abl_ABL1_Y	Q14498	RBM39	P00519	ABL1	Y95	P102Q	102	Missense	distal	7	no	8.709	8.742	PhosphoSitePlus;EPSD	ICGC;COSMIC	7.039	Up-regulation
TK_Abl_ABL1_Y	Q14498	RBM39	P00519	ABL1	Y95	P98S	98	Missense	distal	3	no	8.709	5.573	PhosphoSitePlus;EPSD	ICGC	7.039	Loss
TK_Abl_ABL1_Y	Q14498	RBM39	P00519	ABL1	Y99	P102Q	102	Missense	distal	3	no	11.761	8.746	EPSD;PhosphoSitePlus	ICGC;COSMIC	7.039	Down-regulation
TK_Abl_ABL1_Y	Q14498	RBM39	P00519	ABL1	Y99	P98S	98	Missense	proximal	-1	no	11.761	10.171	EPSD;PhosphoSitePlus	ICGC	7.039	Down-regulation
TK_Abl_ABL1_Y	P55211	CASP9	P00519	ABL1	Y397	S392L	392	Missense	distal	-5	no	9.559	7.941	EPSD;PhosphoSitePlus	ICGC;COSMIC	7.039	Down-regulation
TK_Abl_ABL1_Y	P55211	CASP9	P00519	ABL1	Y397	A390D	390	Missense	distal	-7	no	9.559	9.723	EPSD;PhosphoSitePlus	ICGC	7.039	Up-regulation
TK_Abl_ABL1_Y	P50402	EMD	P00519	ABL1	Y19	G24W	24	Missense	distal	5	no	6.841	7.120	EPSD	ICGC;COSMIC	7.039	Gain
TK_Abl_ABL1_Y	P50402	EMD	P00519	ABL1	Y105	E107D	107	Missense	proximal	2	no	7.479	7.672	EPSD	ICGC	7.039	Up-regulation
TK_Abl_ABL1_Y	P50402	EMD	P00519	ABL1	Y105	E109K	109	Missense	distal	4	no	7.479	7.105	EPSD	ICGC;COSMIC	7.039	Down-regulation
TK_Abl_ABL1_Y	P50402	EMD	P00519	ABL1	Y155	M154I	154	Missense	proximal	-1	no	8.230	10.907	EPSD	ICGC;COSMIC	7.039	Up-regulation
TK_Abl_ABL1_Y	P50402	EMD	P00519	ABL1	Y155	G156C	156	Missense	proximal	1	no	8.230	7.397	EPSD	ICGC;COSMIC	7.039	Down-regulation
TK_Abl_ABL1_Y	P50402	EMD	P00519	ABL1	Y167	P169H	169	Missense	proximal	2	no	7.905	7.792	PhosphoSitePlus	ICGC;COSMIC	7.039	Down-regulation
TK_Abl_ABL1_Y	P50402	EMD	P00519	ABL1	Y167	V170F	170	Missense	distal	3	no	7.905	7.916	PhosphoSitePlus	ICGC	7.039	Up-regulation
TK_Abl_ABL1_Y	P50402	EMD	P00519	ABL1	Y167	R174S	174	Missense	distal	7	no	7.905	7.891	PhosphoSitePlus	ICGC;COSMIC	7.039	Down-regulation
TK_Abl_ABL1_Y	P16333	NCK1	P00519	ABL1	Y105	L104F	104	Missense	proximal	-1	no	9.116	8.329	PhosphoSitePlus	ICGC	7.039	Down-regulation
TK_Abl_ABL1_Y	O15162	PLSCR1	P00519	ABL1	Y74	A81V	81	Missense	distal	7	no	9.875	9.908	EPSD;PhosphoSitePlus	ICGC;COSMIC	7.039	Up-regulation
TK_Abl_ABL1_Y	P43351	RAD52	P00519	ABL1	Y104	G101D	101	Missense	distal	-3	no	8.111	8.346	PhosphoSitePlus	ICGC	7.039	Up-regulation
TK_Abl_ABL1_Y	P43351	RAD52	P00519	ABL1	Y205	P198L	198	Missense	distal	-7	no	10.511	10.321	EPSD	ICGC;COSMIC	7.039	Down-regulation
TK_Abl_ABL1_Y	P43351	RAD52	P00519	ABL1	Y205	E201V	201	Missense	distal	-4	no	10.511	9.160	EPSD	ICGC;COSMIC	7.039	Down-regulation
TK_Abl_ABL1_Y	P43351	RAD52	P00519	ABL1	Y205	P198T	198	Missense	distal	-7	no	10.511	10.887	EPSD	ICGC	7.039	Up-regulation
TK_Abl_ABL1_Y	Q9Y6N7	ROBO1	P00519	ABL1	Y1114	K1121M	1121	Missense	distal	7	no	8.926	8.943	PhosphoSitePlus;EPSD	ICGC;COSMIC	7.039	Up-regulation
TK_Abl_ABL1_Y	P46109	CRKL	P00519	ABL1	Y15	S9L	9	Missense	distal	-6	no	7.956	7.785	EPSD	ICGC;COSMIC	7.039	Down-regulation
TK_Abl_ABL1_Y	P46109	CRKL	P00519	ABL1	Y61	E54K	54	Missense	distal	-7	no	8.719	8.961	EPSD	ICGC;COSMIC	7.039	Up-regulation
TK_Abl_ABL1_Y	P46109	CRKL	P00519	ABL1	Y61	N64I	64	Missense	distal	3	no	8.719	8.110	EPSD	ICGC;COSMIC	7.039	Down-regulation
TK_Abl_ABL1_Y	P46109	CRKL	P00519	ABL1	Y105	R104S	104	Missense	proximal	-1	no	7.660	7.882	EPSD	ICGC	7.039	Up-regulation
TK_Abl_ABL1_Y	P46109	CRKL	P00519	ABL1	Y105	P109T	109	Missense	distal	4	no	7.660	7.581	EPSD	ICGC;COSMIC	7.039	Down-regulation
TK_Abl_ABL1_Y	P46109	CRKL	P00519	ABL1	Y132	P135S	135	Missense	distal	3	no	8.338	5.202	EPSD	ICGC;COSMIC	7.039	Loss
TK_Abl_ABL1_Y	P46109	CRKL	P00519	ABL1	Y132	F134S	134	Missense	proximal	2	no	8.338	9.234	EPSD	ICGC;COSMIC	7.039	Up-regulation
TK_Abl_ABL1_Y	P15498	VAV1	P00519	ABL1	Y142	G144D	144	Missense	proximal	2	no	10.363	10.428	EPSD	ICGC;COSMIC	7.039	Up-regulation
TK_Abl_ABL1_Y	P15498	VAV1	P00519	ABL1	Y142	D140N	140	Missense	proximal	-2	no	10.363	10.959	EPSD	ICGC;COSMIC	7.039	Up-regulation
TK_Abl_ABL1_Y	P15498	VAV1	P00519	ABL1	Y142	D138G	138	Missense	distal	-4	no	10.363	10.602	EPSD	ICGC	7.039	Up-regulation
TK_Abl_ABL1_Y	P15498	VAV1	P00519	ABL1	Y160	E167V	167	Missense	distal	7	no	7.926	7.963	EPSD	ICGC	7.039	Up-regulation
TK_Abl_ABL1_Y	P15498	VAV1	P00519	ABL1	Y160	E157D	157	Missense	distal	-3	no	7.926	7.278	EPSD	ICGC;COSMIC	7.039	Down-regulation
TK_Abl_ABL1_Y	P15498	VAV1	P00519	ABL1	Y160	E166A	166	Missense	distal	6	no	7.926	7.988	EPSD	ICGC;COSMIC	7.039	Up-regulation
TK_Abl_ABL1_Y	P15498	VAV1	P00519	ABL1	Y160	E154A	154	Missense	distal	-6	no	7.926	7.754	EPSD	ICGC;COSMIC	7.039	Down-regulation
TK_Abl_ABL1_Y	P15498	VAV1	P00519	ABL1	Y174	E167V	167	Missense	distal	-7	no	10.850	11.226	PhosphoSitePlus;EPSD	ICGC	7.039	Up-regulation
TK_Abl_ABL1_Y	P15498	VAV1	P00519	ABL1	Y174	E169K	169	Missense	distal	-5	no	10.850	11.059	PhosphoSitePlus;EPSD	ICGC	7.039	Up-regulation
TK_Abl_ABL1_Y	P15498	VAV1	P00519	ABL1	Y174	E172D	172	Missense	proximal	-2	no	10.850	10.388	PhosphoSitePlus;EPSD	ICGC	7.039	Down-regulation
TK_Abl_ABL1_Y	P15498	VAV1	P00519	ABL1	Y267	Q268K	268	Missense	proximal	1	no	9.143	8.839	EPSD;PhosphoSitePlus	ICGC;COSMIC	7.039	Down-regulation
TK_Abl_ABL1_Y	Q9UPY6	WASF3	P00519	ABL1	Y151	Y151C	151	Missense	central	0	yes	11.116	0.000	EPSD;PhosphoSitePlus	ICGC;COSMIC	7.039	Loss
TK_Abl_ABL1_Y	Q9UPY6	WASF3	P00519	ABL1	Y151	P154H	154	Missense	distal	3	no	11.116	7.899	EPSD;PhosphoSitePlus	ICGC;COSMIC	7.039	Down-regulation
TK_Abl_ABL1_Y	Q9UPY6	WASF3	P00519	ABL1	Y151	F158S	158	Missense	distal	7	no	11.116	11.185	EPSD;PhosphoSitePlus	ICGC;COSMIC	7.039	Up-regulation
TK_Abl_ABL1_Y	Q9UPY6	WASF3	P00519	ABL1	Y248	V245F	245	Missense	distal	-3	no	11.586	10.249	EPSD;PhosphoSitePlus	ICGC	7.039	Down-regulation
TK_Abl_ABL1_Y	Q9UPY6	WASF3	P00519	ABL1	Y248	V245I	245	Missense	distal	-3	no	11.586	11.674	EPSD;PhosphoSitePlus	ICGC;COSMIC;GDSC;CCLE	7.039	Up-regulation
TK_Abl_ABL1_Y	Q9UPY6	WASF3	P00519	ABL1	Y286	R287W	287	Missense	proximal	1	no	8.322	5.546	EPSD	ICGC	7.039	Loss
TK_Abl_ABL1_Y	Q9UPY6	WASF3	P00519	ABL1	Y286	S292L	292	Missense	distal	6	no	8.322	7.624	EPSD	ICGC;COSMIC	7.039	Down-regulation
TK_Abl_ABL1_Y	Q9UPY6	WASF3	P00519	ABL1	Y337	G342R	342	Missense	distal	5	no	10.219	9.866	PhosphoSitePlus;EPSD	ICGC;COSMIC	7.039	Down-regulation
TK_Abl_ABL1_Y	Q9UPY6	WASF3	P00519	ABL1	Y486	R481H	481	Missense	distal	-5	no	10.888	9.119	EPSD;PhosphoSitePlus	ICGC;COSMIC	7.039	Down-regulation
TK_Abl_ABL1_Y	Q9UPY6	WASF3	P00519	ABL1	Y486	I482V	482	Missense	distal	-4	no	10.888	10.792	EPSD;PhosphoSitePlus	ICGC	7.039	Down-regulation
TK_Abl_ABL1_Y	P17844	DDX5	P00519	ABL1	Y97	A103E	103	Missense	distal	6	no	10.141	10.079	EPSD	ICGC	7.039	Down-regulation
TK_Abl_ABL1_Y	P17844	DDX5	P00519	ABL1	Y97	P90Q	90	Missense	distal	-7	no	10.141	10.533	EPSD	ICGC;COSMIC	7.039	Up-regulation
TK_Abl_ABL1_Y	P17844	DDX5	P00519	ABL1	Y297	I300V	300	Missense	distal	3	no	5.880	7.397	EPSD	ICGC;COSMIC	7.039	Gain
TK_Abl_ABL1_Y	P17844	DDX5	P00519	ABL1	Y518	R516S	516	Missense	proximal	-2	no	6.907	7.675	EPSD	ICGC;COSMIC	7.039	Gain
TK_Abl_ABL1_Y	P17844	DDX5	P00519	ABL1	Y518	L522R	522	Missense	distal	4	no	6.907	7.308	EPSD	ICGC;COSMIC	7.039	Gain
TK_Abl_ABL1_Y	P17844	DDX5	P00519	ABL1	Y535	T541S	541	Missense	distal	6	no	10.897	10.994	EPSD	ICGC;COSMIC	7.039	Up-regulation
TK_Abl_ABL1_Y	P17844	DDX5	P00519	ABL1	Y535	G533A	533	Missense	proximal	-2	no	10.897	10.562	EPSD	ICGC;COSMIC	7.039	Down-regulation
TK_Abl_ABL1_Y	P17844	DDX5	P00519	ABL1	Y593	Y595C	595	Missense	proximal	2	no	16.480	16.565	PhosphoSitePlus	ICGC;COSMIC	7.039	Up-regulation
TK_Abl_ABL1_Y	P17844	DDX5	P00519	ABL1	Y593	G587C	587	Missense	distal	-6	no	16.480	16.488	PhosphoSitePlus	ICGC;COSMIC	7.039	Up-regulation
TK_Abl_ABL1_Y	P17844	DDX5	P00519	ABL1	Y595	Y595C	595	Missense	central	0	yes	8.959	0.000	EPSD	ICGC;COSMIC	7.039	Loss
TK_Abl_ABL1_Y	P17275	JUNB	P00519	ABL1	Y109	Q108H	108	Missense	proximal	-1	no	5.971	7.189	EPSD	ICGC;COSMIC	7.039	Gain
TK_Abl_ABL1_Y	P17275	JUNB	P00519	ABL1	Y173	G171C	171	Missense	proximal	-2	no	12.366	11.730	EPSD;PhosphoSitePlus	ICGC;COSMIC	7.039	Down-regulation
TK_Abl_ABL1_Y	P17275	JUNB	P00519	ABL1	Y173	G168E	168	Missense	distal	-5	no	12.366	12.455	EPSD;PhosphoSitePlus	ICGC;COSMIC	7.039	Up-regulation
TK_Abl_ABL1_Y	P17275	JUNB	P00519	ABL1	Y173	A167T	167	Missense	distal	-6	no	12.366	12.353	EPSD;PhosphoSitePlus	ICGC;COSMIC	7.039	Down-regulation
TK_Abl_ABL1_Y	P17275	JUNB	P00519	ABL1	Y173	P176S	176	Missense	distal	3	no	12.366	9.230	EPSD;PhosphoSitePlus	ICGC	7.039	Down-regulation
TK_Abl_ABL1_Y	P17275	JUNB	P00519	ABL1	Y173	G168R	168	Missense	distal	-5	no	12.366	12.771	EPSD;PhosphoSitePlus	ICGC	7.039	Up-regulation
TK_Abl_ABL1_Y	P17275	JUNB	P00519	ABL1	Y173	E177K	177	Missense	distal	4	no	12.366	11.991	EPSD;PhosphoSitePlus	ICGC	7.039	Down-regulation
TK_Abl_ABL1_Y	P17275	JUNB	P00519	ABL1	Y188	L185I	185	Missense	distal	-3	no	7.733	8.389	PhosphoSitePlus;EPSD	ICGC;COSMIC	7.039	Up-regulation
TK_Abl_ABL1_Y	P17275	JUNB	P00519	ABL1	Y188	S187R	187	Missense	proximal	-1	no	7.733	7.511	PhosphoSitePlus;EPSD	ICGC	7.039	Down-regulation
TK_Abl_ABL1_Y	P17275	JUNB	P00519	ABL1	Y188	A191P	191	Missense	distal	3	no	7.733	11.835	PhosphoSitePlus;EPSD	ICGC;COSMIC	7.039	Up-regulation
TK_Abl_ABL1_Y	O14818	PSMA7	P00519	ABL1	Y153	A160T	160	Missense	distal	7	no	11.538	11.590	PhosphoSitePlus;EPSD	ICGC	7.039	Up-regulation
TK_Abl_ABL1_Y	Q9UPN9	TRIM33	P00519	ABL1	Y1018	P1021L	1021	Missense	distal	3	no	11.528	8.951	EPSD	ICGC;COSMIC	7.039	Down-regulation
TK_Abl_ABL1_Y	Q9UPN9	TRIM33	P00519	ABL1	Y1018	K1013T	1013	Missense	distal	-5	no	11.528	11.901	EPSD	ICGC	7.039	Up-regulation
TK_Abl_ABL1_Y	P46527	CDKN1B	P00519	ABL1	Y88	Y89H	89	Missense	proximal	1	no	9.490	7.888	EPSD;PhosphoSitePlus	ICGC;COSMIC	7.039	Down-regulation
TK_Abl_ABL1_Y	P46527	CDKN1B	P00519	ABL1	Y89	Y89H	89	Missense	central	0	yes	10.249	0.000	PhosphoSitePlus;EPSD	ICGC;COSMIC	7.039	Loss
TK_Abl_ABL1_Y	Q14980	NUMA1	P00519	ABL1	Y827	F831L	831	Missense	distal	4	no	7.904	8.088	EPSD	ICGC	7.039	Up-regulation
TK_Abl_ABL1_Y	P06400	RB1	P00519	ABL1	Y805	G801E	801	Missense	distal	-4	no	10.355	11.403	PhosphoSitePlus	ICGC	7.039	Up-regulation
TK_Abl_ABL1_Y	Q00987	MDM2	P00519	ABL1	Y394	S400C	400	Missense	distal	6	no	10.889	10.043	PhosphoSitePlus;EPSD	ICGC;COSMIC	7.039	Down-regulation
TK_Abl_ABL1_Y	Q00987	MDM2	P00519	ABL1	Y394	E390Q	390	Missense	distal	-4	no	10.889	9.403	PhosphoSitePlus;EPSD	ICGC;COSMIC	7.039	Down-regulation
TK_Abl_ABL1_Y	Q00987	MDM2	P00519	ABL1	Y405	S400C	400	Missense	distal	-5	no	8.088	6.088	EPSD;PhosphoSitePlus	ICGC;COSMIC	7.039	Loss
TK_Abl_ABL1_Y	Q16531	DDB1	P00519	ABL1	Y182	R188G	188	Missense	distal	6	no	10.384	10.277	PhosphoSitePlus;EPSD	ICGC;COSMIC	7.039	Down-regulation
TK_Abl_ABL1_Y	Q16531	DDB1	P00519	ABL1	Y182	R188W	188	Missense	distal	6	no	10.384	9.870	PhosphoSitePlus;EPSD	ICGC;COSMIC	7.039	Down-regulation
TK_Abl_ABL1_Y	Q16531	DDB1	P00519	ABL1	Y182	T177N	177	Missense	distal	-5	no	10.384	9.509	PhosphoSitePlus;EPSD	ICGC;COSMIC	7.039	Down-regulation
TK_Abl_ABL1_Y	Q16531	DDB1	P00519	ABL1	Y718	T714K	714	Missense	distal	-4	no	7.222	6.478	EPSD;PhosphoSitePlus	ICGC	7.039	Loss
TK_Abl_ABL1_Y	Q16531	DDB1	P00519	ABL1	Y828	T827I	827	Missense	proximal	-1	no	6.388	8.305	EPSD	ICGC	7.039	Gain
TK_Abl_ABL1_Y	P17931	LGALS3	P00519	ABL1	Y79	G85S	85	Missense	distal	6	no	9.439	9.683	EPSD;PhosphoSitePlus	ICGC;COSMIC	7.039	Up-regulation
TK_Abl_ABL1_Y	P17931	LGALS3	P00519	ABL1	Y107	Y101S	101	Missense	distal	-6	no	10.453	10.580	EPSD;PhosphoSitePlus	ICGC;COSMIC	7.039	Up-regulation
TK_Abl_ABL1_Y	P17931	LGALS3	P00519	ABL1	Y107	P113T	113	Missense	distal	6	no	10.453	10.384	EPSD;PhosphoSitePlus	ICGC;COSMIC	7.039	Down-regulation
TK_Abl_ABL1_Y	P17931	LGALS3	P00519	ABL1	Y118	G124V	124	Missense	distal	6	no	8.729	9.116	PhosphoSitePlus;EPSD	ICGC	7.039	Up-regulation
TK_Abl_ABL1_Y	P17931	LGALS3	P00519	ABL1	Y118	G125V	125	Missense	distal	7	no	8.729	8.757	PhosphoSitePlus;EPSD	ICGC;COSMIC	7.039	Up-regulation
TK_Abl_ABL1_Y	P17931	LGALS3	P00519	ABL1	Y118	P113T	113	Missense	distal	-5	no	8.729	9.271	PhosphoSitePlus;EPSD	ICGC;COSMIC	7.039	Up-regulation
TK_Abl_ABL1_Y	P35222	CTNNB1	P00519	ABL1	Y489	L491S	491	Missense	proximal	2	no	10.410	11.893	PhosphoSitePlus;EPSD	ICGC	7.039	Up-regulation
TK_Abl_ABL1_Y	P35222	CTNNB1	P00519	ABL1	Y716	R710H	710	Missense	distal	-6	no	7.966	7.794	EPSD	ICGC;COSMIC	7.039	Down-regulation
TK_Abl_ABL1_Y	P43403	ZAP70	P00519	ABL1	Y69	G67S	67	Missense	proximal	-2	no	6.877	7.194	EPSD	ICGC;COSMIC	7.039	Gain
TK_Abl_ABL1_Y	P43403	ZAP70	P00519	ABL1	Y69	E62D	62	Missense	distal	-7	no	6.877	7.149	EPSD	ICGC	7.039	Gain
TK_Abl_ABL1_Y	P43403	ZAP70	P00519	ABL1	Y198	L200M	200	Missense	proximal	2	no	6.376	7.200	EPSD	ICGC;COSMIC	7.039	Gain
TK_Abl_ABL1_Y	P43403	ZAP70	P00519	ABL1	Y221	C222F	222	Missense	proximal	1	no	10.683	9.447	EPSD	ICGC;COSMIC	7.039	Down-regulation
TK_Abl_ABL1_Y	P43403	ZAP70	P00519	ABL1	Y221	E225D	225	Missense	distal	4	no	10.683	10.556	EPSD	ICGC	7.039	Down-regulation
TK_Abl_ABL1_Y	P43403	ZAP70	P00519	ABL1	Y221	A218V	218	Missense	distal	-3	no	10.683	10.169	EPSD	ICGC;GDSC;CCLE	7.039	Down-regulation
TK_Abl_ABL1_Y	P43403	ZAP70	P00519	ABL1	Y221	A218T	218	Missense	distal	-3	no	10.683	10.021	EPSD	ICGC	7.039	Down-regulation
TK_Abl_ABL1_Y	P43403	ZAP70	P00519	ABL1	Y319	K326N	326	Missense	distal	7	no	13.297	13.303	PhosphoSitePlus	ICGC	7.039	Up-regulation
TK_Abl_ABL1_Y	P43403	ZAP70	P00519	ABL1	Y319	P318L	318	Missense	proximal	-1	no	13.297	13.189	PhosphoSitePlus	ICGC;COSMIC	7.039	Down-regulation
TK_Abl_ABL1_Y	P43403	ZAP70	P00519	ABL1	Y597	Q591K	591	Missense	distal	-6	no	9.155	9.000	EPSD	ICGC;COSMIC	7.039	Down-regulation
TK_Abl_ABL1_Y	P43403	ZAP70	P00519	ABL1	Y598	Q591K	591	Missense	distal	-7	no	7.684	7.454	EPSD	ICGC;COSMIC	7.039	Down-regulation
TK_Abl_ABL1_Y	P15391	CD19	P00519	ABL1	Y378	P376T	376	Missense	proximal	-2	no	7.896	7.852	EPSD	ICGC;COSMIC	7.039	Down-regulation
TK_Abl_ABL1_Y	P15391	CD19	P00519	ABL1	Y439	G438C	438	Missense	proximal	-1	no	6.254	8.840	EPSD	ICGC	7.039	Gain
TK_Abl_ABL1_Y	P15391	CD19	P00519	ABL1	Y500	S497Y	497	Missense	distal	-3	no	7.261	7.296	EPSD	ICGC;COSMIC	7.039	Up-regulation
TK_Abl_ABL1_Y	P15391	CD19	P00519	ABL1	Y500	L507M	507	Missense	distal	7	no	7.261	7.290	EPSD	ICGC	7.039	Up-regulation
TK_Abl_ABL1_Y	P15391	CD19	P00519	ABL1	Y500	S499T	499	Missense	proximal	-1	no	7.261	8.284	EPSD	ICGC	7.039	Up-regulation
TK_Abl_ABL1_Y	P15391	CD19	P00519	ABL1	Y500	Q498H	498	Missense	proximal	-2	no	7.261	6.622	EPSD	ICGC	7.039	Loss
TK_Abl_ABL1_Y	P15391	CD19	P00519	ABL1	Y508	R514S	514	Missense	distal	6	no	9.625	9.762	PhosphoSitePlus	ICGC;COSMIC	7.039	Up-regulation
TK_Abl_ABL1_Y	P15391	CD19	P00519	ABL1	Y508	P511L	511	Missense	distal	3	no	9.625	7.048	PhosphoSitePlus	ICGC;COSMIC	7.039	Down-regulation
TK_Abl_ABL1_Y	P15391	CD19	P00519	ABL1	Y508	R514H	514	Missense	distal	6	no	9.625	9.611	PhosphoSitePlus	ICGC;COSMIC	7.039	Down-regulation
TK_Abl_ABL1_Y	P15391	CD19	P00519	ABL1	Y508	R514C	514	Missense	distal	6	no	9.625	8.916	PhosphoSitePlus	ICGC;COSMIC	7.039	Down-regulation
TK_Abl_ABL1_Y	P15391	CD19	P00519	ABL1	Y508	A510S	510	Missense	proximal	2	no	9.625	9.823	PhosphoSitePlus	ICGC	7.039	Up-regulation
TK_Abl_ABL1_Y	P15391	CD19	P00519	ABL1	Y508	L507M	507	Missense	proximal	-1	no	9.625	8.408	PhosphoSitePlus	ICGC	7.039	Down-regulation
TK_Abl_ABL1_Y	P15391	CD19	P00519	ABL1	Y508	A509V	509	Missense	proximal	1	no	9.625	8.608	PhosphoSitePlus	ICGC;COSMIC	7.039	Down-regulation
TK_Abl_ABL1_Y	P15391	CD19	P00519	ABL1	Y531	E525K	525	Missense	distal	-6	no	7.945	7.734	EPSD	ICGC;COSMIC	7.039	Down-regulation
TK_Abl_ABL1_Y	P15391	CD19	P00519	ABL1	Y531	A528T	528	Missense	distal	-3	no	7.945	7.282	EPSD	ICGC;COSMIC	7.039	Down-regulation
TK_Abl_ABL1_Y	Q99638	RAD9A	P00519	ABL1	Y28	R22G	22	Missense	distal	-6	no	7.846	7.628	PhosphoSitePlus	ICGC	7.039	Down-regulation
TK_Abl_ABL1_Y	Q99638	RAD9A	P00519	ABL1	Y28	L29R	29	Missense	proximal	1	no	7.846	9.065	PhosphoSitePlus	ICGC	7.039	Up-regulation
TK_Abl_ABL1_Y	O15269	SPTLC1	P00519	ABL1	Y18	M13T	13	Missense	distal	-5	no	7.111	8.528	EPSD	ICGC;COSMIC	7.039	Up-regulation
TK_Abl_ABL1_Y	O15269	SPTLC1	P00519	ABL1	Y164	A161D	161	Missense	distal	-3	no	8.622	8.202	PhosphoSitePlus	ICGC	7.039	Down-regulation
TK_Abl_ABL1_Y	Q9Y6H1	CHCHD2	P00519	ABL1	Y99	P95T	95	Missense	distal	-4	no	11.718	11.081	PhosphoSitePlus	ICGC	7.039	Down-regulation
TK_Abl_ABL1_Y	Q13043	STK4	P00519	ABL1	Y41	G42V	42	Missense	proximal	1	no	6.841	7.370	EPSD	ICGC;COSMIC	7.039	Gain
TK_Abl_ABL1_Y	Q13043	STK4	P00519	ABL1	Y45	K46N	46	Missense	proximal	1	no	9.345	10.016	EPSD	ICGC;COSMIC	7.039	Up-regulation
TK_Abl_ABL1_Y	Q13043	STK4	P00519	ABL1	Y45	V44I	44	Missense	proximal	-1	no	9.345	11.111	EPSD	ICGC;COSMIC;GDSC;CCLE	7.039	Up-regulation
TK_Abl_ABL1_Y	Q13043	STK4	P00519	ABL1	Y45	E38K	38	Missense	distal	-7	no	9.345	9.586	EPSD	ICGC;COSMIC	7.039	Up-regulation
TK_Abl_ABL1_Y	Q13043	STK4	P00519	ABL1	Y45	G42V	42	Missense	distal	-3	no	9.345	9.484	EPSD	ICGC;COSMIC	7.039	Up-regulation
TK_Abl_ABL1_Y	Q13043	STK4	P00519	ABL1	Y45	V44L	44	Missense	proximal	-1	no	9.345	9.652	EPSD	ICGC	7.039	Up-regulation
TK_Abl_ABL1_Y	O94916	NFAT5	P00519	ABL1	Y143	R138Q	138	Missense	distal	-5	no	7.417	7.410	PhosphoSitePlus	ICGC;COSMIC	7.039	Down-regulation
TK_Abl_ABL1_Y	P07203	GPX1	P00519	ABL1	Y98	L96R	96	Missense	proximal	-2	no	8.133	8.343	PhosphoSitePlus	ICGC;COSMIC	7.039	Up-regulation
TK_Abl_ABL1_Y	Q9H2X6	HIPK2	P00519	ABL1	Y443	P442L	442	Missense	proximal	-1	no	9.217	9.108	EPSD	ICGC;COSMIC	7.039	Down-regulation
TK_Abl_ABL1_Y	Q9H2X6	HIPK2	P00519	ABL1	Y443	R437S	437	Missense	distal	-6	no	9.217	9.145	EPSD	ICGC;COSMIC	7.039	Down-regulation
TK_Abl_ABL1_Y	Q14847	LASP1	P00519	ABL1	Y44	L39P	39	Missense	distal	-5	no	6.347	7.746	EPSD	ICGC	7.039	Gain
TK_Abl_ABL1_Y	Q14847	LASP1	P00519	ABL1	Y171	Q177H	177	Missense	distal	6	no	10.568	9.701	PhosphoSitePlus	ICGC;COSMIC	7.039	Down-regulation
TK_Abl_ABL1_Y	O95433	AHSA1	P00519	ABL1	Y223	E230D	230	Missense	distal	7	no	9.095	9.106	PhosphoSitePlus	ICGC;COSMIC	7.039	Up-regulation
TK_Abl_ABL1_Y	P25490	YY1	P00519	ABL1	Y383	C390F	390	Missense	distal	7	no	8.028	8.027	EPSD	ICGC	7.039	Down-regulation
TK_Abl_ABL1_Y	P42768	WAS	P00519	ABL1	Y102	Y102H	102	Missense	central	0	yes	7.430	0.000	EPSD	ICGC;COSMIC	7.039	Loss
TK_Abl_ABL1_Y	P42768	WAS	P00519	ABL1	Y102	Q99H	99	Missense	distal	-3	no	7.430	6.651	EPSD	ICGC	7.039	Loss
TK_Abl_ABL1_Y	P42768	WAS	P00519	ABL1	Y291	D292Y	292	Missense	proximal	1	no	9.254	8.802	PhosphoSitePlus	ICGC;COSMIC	7.039	Down-regulation
TK_Abl_ABL1_Y	P42768	WAS	P00519	ABL1	Y291	A284S	284	Missense	distal	-7	no	9.254	9.303	PhosphoSitePlus	ICGC	7.039	Up-regulation
TK_Abl_ABL1_Y	P42768	WAS	P00519	ABL1	Y291	I290M	290	Missense	proximal	-1	no	9.254	6.577	PhosphoSitePlus	ICGC;COSMIC	7.039	Loss
TK_Abl_ABL1_Y	P42768	WAS	P00519	ABL1	Y291	E285K	285	Missense	distal	-6	no	9.254	9.043	PhosphoSitePlus	ICGC;COSMIC	7.039	Down-regulation
TK_Abl_ABL1_Y	P11387	TOP1	P00519	ABL1	Y125	V127I	127	Missense	proximal	2	no	8.928	9.903	EPSD	ICGC	7.039	Up-regulation
TK_Abl_ABL1_Y	P11387	TOP1	P00519	ABL1	Y125	D118Y	118	Missense	distal	-7	no	8.928	8.539	EPSD	ICGC;COSMIC	7.039	Down-regulation
TK_Abl_ABL1_Y	P11387	TOP1	P00519	ABL1	Y426	G422V	422	Missense	distal	-4	no	7.303	6.999	EPSD	ICGC	7.039	Loss
TK_Abl_ABL1_Y	P11387	TOP1	P00519	ABL1	Y426	P431T	431	Missense	distal	5	no	7.303	7.071	EPSD	ICGC;COSMIC	7.039	Down-regulation
TK_Abl_ABL1_Y	P11387	TOP1	P00519	ABL1	Y537	N539D	539	Missense	proximal	2	no	7.140	6.797	EPSD	ICGC;COSMIC	7.039	Loss
TK_Abl_ABL1_Y	P11387	TOP1	P00519	ABL1	Y537	S534F	534	Missense	distal	-3	no	7.140	5.717	EPSD	ICGC;COSMIC;CCLE	7.039	Loss
TK_Abl_ABL1_Y	P11387	TOP1	P00519	ABL1	Y538	N539D	539	Missense	proximal	1	no	6.782	7.082	EPSD	ICGC;COSMIC	7.039	Gain
Other_CDC7_CDC7_ST	P19338	NCL	O00311	CDC7	S67	A61S	61	Missense	distal	-6	no	63.404	65.128	EPSD	ICGC;COSMIC	65.097	Gain
Other_CDC7_CDC7_ST	P19338	NCL	O00311	CDC7	T76	P77T	77	Missense	proximal	1	no	81.375	60.154	EPSD;PhosphoSitePlus	ICGC	65.097	Loss
Other_CDC7_CDC7_ST	P19338	NCL	O00311	CDC7	T76	A81E	81	Missense	distal	5	no	81.375	81.300	EPSD;PhosphoSitePlus	ICGC	65.097	Down-regulation
Other_CDC7_CDC7_ST	P19338	NCL	O00311	CDC7	T76	T69K	69	Missense	distal	-7	no	81.375	78.959	EPSD;PhosphoSitePlus	ICGC	65.097	Down-regulation
Other_CDC7_CDC7_ST	P19338	NCL	O00311	CDC7	T92	P85Q	85	Missense	distal	-7	no	65.862	61.869	EPSD	ICGC	65.097	Loss
Other_CDC7_CDC7_ST	P19338	NCL	O00311	CDC7	S206	D205E	205	Missense	proximal	-1	no	77.704	80.441	EPSD	ICGC;COSMIC	65.097	Up-regulation
Other_CDC7_CDC7_ST	P19338	NCL	O00311	CDC7	S206	D200E	200	Missense	distal	-6	no	77.704	79.415	EPSD	ICGC	65.097	Up-regulation
Other_CDC7_CDC7_ST	P19338	NCL	O00311	CDC7	S206	D204E	204	Missense	proximal	-2	no	77.704	77.377	EPSD	ICGC	65.097	Down-regulation
Other_CDC7_CDC7_ST	P19338	NCL	O00311	CDC7	S591	T587A	587	Missense	distal	-4	no	77.786	77.987	EPSD	ICGC;COSMIC	65.097	Up-regulation
Other_CDC7_CDC7_ST	P19338	NCL	O00311	CDC7	S591	D593E	593	Missense	proximal	2	no	77.786	79.036	EPSD	ICGC	65.097	Up-regulation
Other_CDC7_CDC7_ST	P19338	NCL	O00311	CDC7	S591	T584N	584	Missense	distal	-7	no	77.786	76.011	EPSD	ICGC	65.097	Down-regulation
Other_CDC7_CDC7_ST	P55081	MFAP1	O00311	CDC7	S116	E121K	121	Missense	distal	5	no	83.039	83.413	PhosphoSitePlus	ICGC;COSMIC	65.097	Up-regulation
Other_CDC7_CDC7_ST	P55081	MFAP1	O00311	CDC7	S132	R126C	126	Missense	distal	-6	no	66.210	65.493	EPSD	ICGC;COSMIC	65.097	Down-regulation
Other_CDC7_CDC7_ST	P55081	MFAP1	O00311	CDC7	S133	R126C	126	Missense	distal	-7	no	82.583	83.041	EPSD	ICGC;COSMIC	65.097	Up-regulation
Other_CDC7_CDC7_ST	P55081	MFAP1	O00311	CDC7	S179	E182Q	182	Missense	distal	3	no	71.787	71.839	EPSD	ICGC;COSMIC	65.097	Up-regulation
Other_CDC7_CDC7_ST	P55081	MFAP1	O00311	CDC7	S401	A405P	405	Missense	distal	4	no	73.140	71.684	EPSD	ICGC	65.097	Down-regulation
Other_CDC7_CDC7_ST	P55081	MFAP1	O00311	CDC7	S401	S404L	404	Missense	distal	3	no	73.140	72.914	EPSD	ICGC;COSMIC	65.097	Down-regulation
Other_CDC7_CDC7_ST	P55081	MFAP1	O00311	CDC7	S401	S401C	401	Missense	central	0	yes	73.140	0.000	EPSD	ICGC;COSMIC	65.097	Loss
Other_CDC7_CDC7_ST	P49736	MCM2	O00311	CDC7	S4	A11S	11	Missense	distal	7	no	75.939	76.287	EPSD;PhosphoSitePlus	ICGC	65.097	Up-regulation
Other_CDC7_CDC7_ST	P49736	MCM2	O00311	CDC7	S5	A11S	11	Missense	distal	6	no	83.157	83.125	PhosphoSitePlus;EPSD	ICGC	65.097	Down-regulation
Other_CDC7_CDC7_ST	P49736	MCM2	O00311	CDC7	S7	A11S	11	Missense	distal	4	no	78.162	77.373	EPSD;PhosphoSitePlus	ICGC	65.097	Down-regulation
Other_CDC7_CDC7_ST	P49736	MCM2	O00311	CDC7	S26	R33Q	33	Missense	distal	7	no	74.298	72.325	EPSD	ICGC	65.097	Down-regulation
Other_CDC7_CDC7_ST	P49736	MCM2	O00311	CDC7	S27	R33Q	33	Missense	distal	6	no	82.312	82.241	EPSD;PhosphoSitePlus	ICGC	65.097	Down-regulation
Other_CDC7_CDC7_ST	P49736	MCM2	O00311	CDC7	S31	R33Q	33	Missense	proximal	2	no	76.100	76.342	EPSD;PhosphoSitePlus	ICGC	65.097	Up-regulation
Other_CDC7_CDC7_ST	P49736	MCM2	O00311	CDC7	S40	R33Q	33	Missense	distal	-7	no	80.370	76.669	EPSD;PhosphoSitePlus	ICGC	65.097	Down-regulation
Other_CDC7_CDC7_ST	P49736	MCM2	O00311	CDC7	S40	S40P	40	Missense	central	0	yes	80.370	0.000	EPSD;PhosphoSitePlus	ICGC;COSMIC	65.097	Loss
Other_CDC7_CDC7_ST	P49736	MCM2	O00311	CDC7	S41	S40P	40	Missense	proximal	-1	no	87.051	83.942	EPSD;PhosphoSitePlus	ICGC;COSMIC	65.097	Down-regulation
Other_CDC7_CDC7_ST	P49736	MCM2	O00311	CDC7	S53	G58V	58	Missense	distal	5	no	80.927	81.978	EPSD;PhosphoSitePlus	ICGC;COSMIC	65.097	Up-regulation
Other_CDC7_CDC7_ST	P49736	MCM2	O00311	CDC7	S53	D51Y	51	Missense	proximal	-2	no	80.927	83.079	EPSD;PhosphoSitePlus	ICGC;COSMIC	65.097	Up-regulation
Other_CDC7_CDC7_ST	P49736	MCM2	O00311	CDC7	S53	S53F	53	Missense	central	0	yes	80.927	0.000	EPSD;PhosphoSitePlus	ICGC	65.097	Loss
Other_CDC7_CDC7_ST	P49736	MCM2	O00311	CDC7	T59	G58V	58	Missense	proximal	-1	no	65.895	63.394	EPSD	ICGC;COSMIC	65.097	Loss
Other_CDC7_CDC7_ST	P49736	MCM2	O00311	CDC7	T59	L63M	63	Missense	distal	4	no	65.895	65.094	EPSD	ICGC;COSMIC	65.097	Loss
Other_CDC7_CDC7_ST	P49736	MCM2	O00311	CDC7	T59	S53F	53	Missense	distal	-6	no	65.895	67.580	EPSD	ICGC	65.097	Up-regulation
Other_CDC7_CDC7_ST	P49736	MCM2	O00311	CDC7	S108	A107S	107	Missense	proximal	-1	no	77.445	78.570	EPSD;PhosphoSitePlus	ICGC	65.097	Up-regulation
Other_CDC7_CDC7_ST	P49736	MCM2	O00311	CDC7	S108	R115Q	115	Missense	distal	7	no	77.445	75.472	EPSD;PhosphoSitePlus	ICGC;COSMIC	65.097	Down-regulation
Other_CDC7_CDC7_ST	P49736	MCM2	O00311	CDC7	S139	E145D	145	Missense	distal	6	no	81.331	81.375	EPSD;PhosphoSitePlus	ICGC;COSMIC	65.097	Up-regulation
Other_CDC7_CDC7_ST	P49736	MCM2	O00311	CDC7	S139	R132C	132	Missense	distal	-7	no	81.331	81.789	EPSD;PhosphoSitePlus	ICGC;COSMIC;CCLE	65.097	Up-regulation
Other_CDC7_CDC7_ST	P49736	MCM2	O00311	CDC7	S220	D221N	221	Missense	proximal	1	no	79.669	60.621	EPSD;PhosphoSitePlus	ICGC;COSMIC	65.097	Loss
Other_CDC7_CDC7_ST	P49736	MCM2	O00311	CDC7	S220	N213S	213	Missense	distal	-7	no	79.669	78.600	EPSD;PhosphoSitePlus	ICGC	65.097	Down-regulation
Other_CDC7_CDC7_ST	P49736	MCM2	O00311	CDC7	S220	N213Y	213	Missense	distal	-7	no	79.669	89.162	EPSD;PhosphoSitePlus	ICGC;COSMIC	65.097	Up-regulation
Other_CDC7_CDC7_ST	P49736	MCM2	O00311	CDC7	S220	V214F	214	Missense	distal	-6	no	79.669	77.921	EPSD;PhosphoSitePlus	ICGC	65.097	Down-regulation
Other_CDC7_CDC7_ST	P49736	MCM2	O00311	CDC7	S381	R375C	375	Missense	distal	-6	no	73.894	73.177	EPSD	ICGC;COSMIC;GDSC;CCLE	65.097	Down-regulation
Other_CDC7_CDC7_ST	P49736	MCM2	O00311	CDC7	S381	A386V	386	Missense	distal	5	no	73.894	75.451	EPSD	ICGC;COSMIC	65.097	Up-regulation
Other_CDC7_CDC7_ST	P49736	MCM2	O00311	CDC7	S381	R377Q	377	Missense	distal	-4	no	73.894	74.155	EPSD	ICGC;COSMIC	65.097	Up-regulation
Other_CDC7_CDC7_ST	P49736	MCM2	O00311	CDC7	S566	R562Q	562	Missense	distal	-4	no	66.076	66.336	EPSD	ICGC;COSMIC	65.097	Up-regulation
Other_CDC7_CDC7_ST	P49736	MCM2	O00311	CDC7	S566	R562W	562	Missense	distal	-4	no	66.076	67.694	EPSD	ICGC;COSMIC	65.097	Up-regulation
Other_CDC7_CDC7_ST	P49736	MCM2	O00311	CDC7	T598	D594Y	594	Missense	distal	-4	no	63.683	66.258	EPSD	ICGC	65.097	Gain
Other_CDC7_CDC7_ST	P49736	MCM2	O00311	CDC7	S759	P761S	761	Missense	proximal	2	no	70.139	74.053	EPSD	ICGC;COSMIC	65.097	Up-regulation
Other_CDC7_CDC7_ST	P49736	MCM2	O00311	CDC7	S759	S754A	754	Missense	distal	-5	no	70.139	73.208	EPSD	ICGC	65.097	Up-regulation
Other_CDC7_CDC7_ST	P49736	MCM2	O00311	CDC7	S759	T757A	757	Missense	proximal	-2	no	70.139	68.240	EPSD	ICGC	65.097	Down-regulation
Other_CDC7_CDC7_ST	O00311	CDC7	O00311	CDC7	S16	E11D	11	Missense	distal	-5	no	70.888	73.910	EPSD	ICGC	65.097	Up-regulation
Other_CDC7_CDC7_ST	O00311	CDC7	O00311	CDC7	S16	P12S	12	Missense	distal	-4	no	70.888	71.555	EPSD	ICGC;COSMIC	65.097	Up-regulation
Other_CDC7_CDC7_ST	O00311	CDC7	O00311	CDC7	S216	R222M	222	Missense	distal	6	no	83.881	83.845	EPSD;PhosphoSitePlus	ICGC;COSMIC	65.097	Down-regulation
Other_CDC7_CDC7_ST	O00311	CDC7	O00311	CDC7	S239	G233R	233	Missense	distal	-6	no	73.820	70.913	EPSD;PhosphoSitePlus	ICGC;COSMIC	65.097	Down-regulation
Other_CDC7_CDC7_ST	O00311	CDC7	O00311	CDC7	S277	D272E	272	Missense	distal	-5	no	89.579	86.557	EPSD;PhosphoSitePlus	ICGC	65.097	Down-regulation
Other_CDC7_CDC7_ST	O00311	CDC7	O00311	CDC7	S318	R319I	319	Missense	proximal	1	no	73.169	73.730	PhosphoSitePlus;EPSD	ICGC;COSMIC	65.097	Up-regulation
Other_CDC7_CDC7_ST	O00311	CDC7	O00311	CDC7	T356	S361I	361	Missense	distal	5	no	65.358	65.578	EPSD	ICGC	65.097	Up-regulation
Other_CDC7_CDC7_ST	Q9HAW4	CLSPN	O00311	CDC7	S67	T69I	69	Missense	proximal	2	no	86.013	86.396	EPSD;PhosphoSitePlus	ICGC	65.097	Up-regulation
Other_CDC7_CDC7_ST	Q9HAW4	CLSPN	O00311	CDC7	S110	T106A	106	Missense	distal	-4	no	100.627	100.828	EPSD;PhosphoSitePlus	ICGC;COSMIC	65.097	Up-regulation
Other_CDC7_CDC7_ST	Q9HAW4	CLSPN	O00311	CDC7	S110	M115I	115	Missense	distal	5	no	100.627	100.240	EPSD;PhosphoSitePlus	ICGC;COSMIC;CCLE	65.097	Down-regulation
Other_CDC7_CDC7_ST	Q9HAW4	CLSPN	O00311	CDC7	S205	E199K	199	Missense	distal	-6	no	65.611	64.518	EPSD	ICGC;COSMIC	65.097	Loss
Other_CDC7_CDC7_ST	Q9HAW4	CLSPN	O00311	CDC7	S205	V198E	198	Missense	distal	-7	no	65.611	58.755	EPSD	ICGC;COSMIC	65.097	Loss
Other_CDC7_CDC7_ST	Q9HAW4	CLSPN	O00311	CDC7	S235	L233F	233	Missense	proximal	-2	no	66.357	66.107	EPSD	ICGC;COSMIC	65.097	Down-regulation
Other_CDC7_CDC7_ST	Q9HAW4	CLSPN	O00311	CDC7	S265	T271N	271	Missense	distal	6	no	81.373	81.240	EPSD;PhosphoSitePlus	ICGC	65.097	Down-regulation
Other_CDC7_CDC7_ST	Q9HAW4	CLSPN	O00311	CDC7	S425	S425N	425	Missense	central	0	yes	66.555	0.000	EPSD	ICGC;COSMIC	65.097	Loss
Other_CDC7_CDC7_ST	Q9HAW4	CLSPN	O00311	CDC7	S480	P474H	474	Missense	distal	-6	no	69.389	71.371	EPSD	ICGC;COSMIC	65.097	Up-regulation
Other_CDC7_CDC7_ST	Q9HAW4	CLSPN	O00311	CDC7	S480	Q477K	477	Missense	distal	-3	no	69.389	69.498	EPSD	ICGC	65.097	Up-regulation
Other_CDC7_CDC7_ST	Q9HAW4	CLSPN	O00311	CDC7	S704	E705Q	705	Missense	proximal	1	no	79.769	68.474	EPSD;PhosphoSitePlus	ICGC;COSMIC	65.097	Down-regulation
Other_CDC7_CDC7_ST	Q9HAW4	CLSPN	O00311	CDC7	S721	S718Y	718	Missense	distal	-3	no	79.382	79.492	EPSD;PhosphoSitePlus	ICGC	65.097	Up-regulation
Other_CDC7_CDC7_ST	Q9HAW4	CLSPN	O00311	CDC7	S968	Q964H	964	Missense	distal	-4	no	69.915	71.177	EPSD	ICGC;COSMIC	65.097	Up-regulation
Other_CDC7_CDC7_ST	Q9HAW4	CLSPN	O00311	CDC7	S1012	E1014D	1014	Missense	proximal	2	no	66.878	65.629	EPSD	ICGC;COSMIC	65.097	Down-regulation
Other_CDC7_CDC7_ST	Q9HAW4	CLSPN	O00311	CDC7	S1096	D1091E	1091	Missense	distal	-5	no	79.421	76.398	EPSD	ICGC;COSMIC	65.097	Down-regulation
Other_CDC7_CDC7_ST	Q9HAW4	CLSPN	O00311	CDC7	T1161	D1155G	1155	Missense	distal	-6	no	80.216	84.786	EPSD	ICGC	65.097	Up-regulation
Other_CDC7_CDC7_ST	Q8TEA8	DTD1	O00311	CDC7	S205	S205Y	205	Missense	central	0	yes	67.939	0.000	EPSD;PhosphoSitePlus	ICGC;COSMIC	65.097	Loss
Other_CDC7_CDC7_ST	P11388	TOP2A	O00311	CDC7	S800	A801D	801	Missense	proximal	1	no	55.055	73.737	EPSD	ICGC	65.097	Gain
Other_CDC7_CDC7_ST	P11388	TOP2A	O00311	CDC7	S802	A801D	801	Missense	proximal	-1	no	70.984	70.979	EPSD	ICGC	65.097	Down-regulation
Other_CDC7_CDC7_ST	P11388	TOP2A	O00311	CDC7	S1106	E1104K	1104	Missense	proximal	-2	no	69.678	70.414	EPSD	ICGC	65.097	Up-regulation
Other_CDC7_CDC7_ST	P11388	TOP2A	O00311	CDC7	S1106	E1109K	1109	Missense	distal	3	no	69.678	69.423	EPSD	ICGC;COSMIC	65.097	Down-regulation
Other_CDC7_CDC7_ST	P11388	TOP2A	O00311	CDC7	S1297	S1302I	1302	Missense	distal	5	no	73.176	73.395	EPSD	ICGC	65.097	Up-regulation
Other_CDC7_CDC7_ST	P11388	TOP2A	O00311	CDC7	S1303	S1302I	1302	Missense	proximal	-1	no	77.940	76.347	EPSD	ICGC	65.097	Down-regulation
Other_CDC7_CDC7_ST	P11388	TOP2A	O00311	CDC7	S1354	P1355S	1355	Missense	proximal	1	no	67.328	63.017	EPSD	ICGC	65.097	Loss
Other_CDC7_CDC7_ST	P11388	TOP2A	O00311	CDC7	S1354	P1350T	1350	Missense	distal	-4	no	67.328	67.627	EPSD	ICGC;COSMIC	65.097	Up-regulation
Other_CDC7_CDC7_ST	P11388	TOP2A	O00311	CDC7	S1377	V1376M	1376	Missense	proximal	-1	no	66.952	67.997	EPSD	ICGC;COSMIC	65.097	Up-regulation
Other_CDC7_CDC7_ST	P11388	TOP2A	O00311	CDC7	S1391	P1395T	1395	Missense	distal	4	no	69.016	70.812	EPSD	ICGC;COSMIC	65.097	Up-regulation
Other_CDC7_CDC7_ST	P11388	TOP2A	O00311	CDC7	S1391	P1394T	1394	Missense	distal	3	no	69.016	69.120	EPSD	ICGC;COSMIC	65.097	Up-regulation
Other_CDC7_CDC7_ST	P11388	TOP2A	O00311	CDC7	S1391	K1385N	1385	Missense	distal	-6	no	69.016	69.661	EPSD	ICGC;COSMIC	65.097	Up-regulation
Other_CDC7_CDC7_ST	P11388	TOP2A	O00311	CDC7	S1423	A1420E	1420	Missense	distal	-3	no	70.745	70.565	EPSD	ICGC;COSMIC	65.097	Down-regulation
Other_CDC7_CDC7_ST	P11388	TOP2A	O00311	CDC7	S1426	A1420E	1420	Missense	distal	-6	no	65.166	67.967	EPSD	ICGC;COSMIC	65.097	Up-regulation
Other_CDC7_CDC7_ST	P11388	TOP2A	O00311	CDC7	S1471	R1464C	1464	Missense	distal	-7	no	71.859	72.317	EPSD	ICGC;COSMIC	65.097	Up-regulation
Other_CDC7_CDC7_ST	P11388	TOP2A	O00311	CDC7	S1471	S1469P	1469	Missense	proximal	-2	no	71.859	73.076	EPSD	ICGC	65.097	Up-regulation
Other_CDC7_CDC7_ST	P11388	TOP2A	O00311	CDC7	S1471	R1466T	1466	Missense	distal	-5	no	71.859	76.514	EPSD	ICGC;COSMIC	65.097	Up-regulation
Other_CDC7_CDC7_ST	P11388	TOP2A	O00311	CDC7	S1471	D1473Y	1473	Missense	proximal	2	no	71.859	68.597	EPSD	ICGC;COSMIC	65.097	Down-regulation
Other_CDC7_CDC7_ST	P11388	TOP2A	O00311	CDC7	S1474	S1469P	1469	Missense	distal	-5	no	73.997	75.399	EPSD	ICGC	65.097	Up-regulation
Other_CDC7_CDC7_ST	P11388	TOP2A	O00311	CDC7	S1474	D1473Y	1473	Missense	proximal	-1	no	73.997	69.660	EPSD	ICGC;COSMIC	65.097	Down-regulation
Other_CDC7_CDC7_ST	Q9UBU7	DBF4	O00311	CDC7	S61	K66N	66	Missense	distal	5	no	70.711	71.053	EPSD	ICGC	65.097	Up-regulation
Other_CDC7_CDC7_ST	Q9UBU7	DBF4	O00311	CDC7	S61	V58F	58	Missense	distal	-3	no	70.711	70.625	EPSD	ICGC	65.097	Down-regulation
Other_CDC7_CDC7_ST	Q9UBU7	DBF4	O00311	CDC7	S118	A111T	111	Missense	distal	-7	no	66.103	69.732	EPSD	ICGC;COSMIC	65.097	Up-regulation
Other_CDC7_CDC7_ST	Q9UBU7	DBF4	O00311	CDC7	S118	Y112N	112	Missense	distal	-6	no	66.103	62.861	EPSD	ICGC;COSMIC	65.097	Loss
Other_CDC7_CDC7_ST	Q9UBU7	DBF4	O00311	CDC7	T194	G200V	200	Missense	distal	6	no	75.044	74.878	EPSD	ICGC	65.097	Down-regulation
Other_CDC7_CDC7_ST	Q9UBU7	DBF4	O00311	CDC7	S195	G200V	200	Missense	distal	5	no	71.299	72.349	EPSD	ICGC	65.097	Up-regulation
Other_CDC7_CDC7_ST	Q9UBU7	DBF4	O00311	CDC7	S259	T265S	265	Missense	distal	6	no	82.872	82.853	EPSD	ICGC	65.097	Down-regulation
Other_CDC7_CDC7_ST	Q9UBU7	DBF4	O00311	CDC7	S259	D256E	256	Missense	distal	-3	no	82.872	82.769	EPSD	ICGC;COSMIC	65.097	Down-regulation
Other_CDC7_CDC7_ST	Q9UBU7	DBF4	O00311	CDC7	S259	M261I	261	Missense	proximal	2	no	82.872	83.677	EPSD	ICGC	65.097	Up-regulation
Other_CDC7_CDC7_ST	Q9UBU7	DBF4	O00311	CDC7	S259	S260N	260	Missense	proximal	1	no	82.872	67.147	EPSD	ICGC	65.097	Down-regulation
Other_CDC7_CDC7_ST	Q9UBU7	DBF4	O00311	CDC7	T281	T281N	281	Missense	central	0	yes	71.885	0.000	EPSD;PhosphoSitePlus	ICGC;COSMIC	65.097	Loss
Other_CDC7_CDC7_ST	Q9UBU7	DBF4	O00311	CDC7	S312	L310I	310	Missense	proximal	-2	no	82.990	82.489	PhosphoSitePlus;EPSD	ICGC;COSMIC	65.097	Down-regulation
Other_CDC7_CDC7_ST	Q9UBU7	DBF4	O00311	CDC7	S359	V365F	365	Missense	distal	6	no	83.320	83.445	EPSD	ICGC;COSMIC	65.097	Up-regulation
Other_CDC7_CDC7_ST	P06748	NPM1	O00311	CDC7	S125	E131D	131	Missense	distal	6	no	79.518	79.562	EPSD	ICGC;COSMIC	65.097	Up-regulation
Other_CDC7_CDC7_ST	P06748	NPM1	O00311	CDC7	S137	R142W	142	Missense	distal	5	no	78.837	80.026	PhosphoSitePlus;EPSD	ICGC	65.097	Up-regulation
Other_CDC7_CDC7_ST	P06748	NPM1	O00311	CDC7	S137	E131D	131	Missense	distal	-6	no	78.837	77.125	PhosphoSitePlus;EPSD	ICGC;COSMIC	65.097	Down-regulation
Other_CDC7_CDC7_ST	P06748	NPM1	O00311	CDC7	T199	R197G	197	Missense	proximal	-2	no	76.935	77.965	EPSD;PhosphoSitePlus	ICGC;COSMIC	65.097	Up-regulation
Other_CDC7_CDC7_ST	P06748	NPM1	O00311	CDC7	T199	A204T	204	Missense	distal	5	no	76.935	77.247	EPSD;PhosphoSitePlus	ICGC;COSMIC	65.097	Up-regulation
Other_CDC7_CDC7_ST	P06748	NPM1	O00311	CDC7	T199	P200A	200	Missense	proximal	1	no	76.935	57.264	EPSD;PhosphoSitePlus	ICGC	65.097	Loss
Other_CDC7_CDC7_ST	P06748	NPM1	O00311	CDC7	S254	S254I	254	Missense	central	0	yes	75.517	0.000	EPSD	ICGC	65.097	Loss
Other_CDC7_CDC7_ST	O75475	PSIP1	O00311	CDC7	S62	K56R	56	Missense	distal	-6	no	70.397	71.442	EPSD	ICGC;COSMIC	65.097	Up-regulation
Other_CDC7_CDC7_ST	O75475	PSIP1	O00311	CDC7	S62	K56N	56	Missense	distal	-6	no	70.397	71.041	EPSD	ICGC;COSMIC	65.097	Up-regulation
Other_CDC7_CDC7_ST	O75475	PSIP1	O00311	CDC7	S94	Q96H	96	Missense	proximal	2	no	68.045	64.034	EPSD	ICGC;COSMIC	65.097	Loss
Other_CDC7_CDC7_ST	O75475	PSIP1	O00311	CDC7	S206	T212N	212	Missense	distal	6	no	95.630	95.497	PhosphoSitePlus	ICGC	65.097	Down-regulation
Other_CDC7_CDC7_ST	O75475	PSIP1	O00311	CDC7	S206	M199V	199	Missense	distal	-7	no	95.630	97.230	PhosphoSitePlus	ICGC;COSMIC	65.097	Up-regulation
Other_CDC7_CDC7_ST	O75475	PSIP1	O00311	CDC7	S206	Q202H	202	Missense	distal	-4	no	95.630	96.893	PhosphoSitePlus	ICGC;COSMIC	65.097	Up-regulation
Other_CDC7_CDC7_ST	O75475	PSIP1	O00311	CDC7	S208	T212N	212	Missense	distal	4	no	73.348	73.436	EPSD	ICGC	65.097	Up-regulation
Other_CDC7_CDC7_ST	O75475	PSIP1	O00311	CDC7	S208	Q202H	202	Missense	distal	-6	no	73.348	78.070	EPSD	ICGC;COSMIC	65.097	Up-regulation
Other_CDC7_CDC7_ST	O75475	PSIP1	O00311	CDC7	T212	T212N	212	Missense	central	0	yes	68.206	0.000	EPSD	ICGC	65.097	Loss
Other_CDC7_CDC7_ST	O75475	PSIP1	O00311	CDC7	S273	T270S	270	Missense	distal	-3	no	66.154	66.304	EPSD	ICGC;COSMIC	65.097	Up-regulation
Other_CDC7_CDC7_ST	O75475	PSIP1	O00311	CDC7	S275	T270S	270	Missense	distal	-5	no	70.158	64.812	EPSD	ICGC;COSMIC	65.097	Loss
Other_CDC7_CDC7_ST	Q9NS91	RAD18	O00311	CDC7	S99	P104H	104	Missense	distal	5	no	74.952	75.015	EPSD	ICGC;COSMIC	65.097	Up-regulation
Other_CDC7_CDC7_ST	Q9NS91	RAD18	O00311	CDC7	S434	V430A	430	Missense	distal	-4	no	75.630	73.835	PhosphoSitePlus	ICGC	65.097	Down-regulation
CMGC_GSK_GSK3B_ST	Q13131	PRKAA1	P49841	GSK3B	T183	N189S	189	Missense	distal	6	no	7.663	7.670	EPSD	ICGC;COSMIC;CCLE	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	Q13131	PRKAA1	P49841	GSK3B	T183	T183K	183	Missense	central	0	yes	7.663	0.000	EPSD	ICGC	6.007	Loss
CMGC_GSK_GSK3B_ST	Q13131	PRKAA1	P49841	GSK3B	S187	N189S	189	Missense	proximal	2	no	8.391	8.923	EPSD	ICGC;COSMIC;CCLE	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	Q13131	PRKAA1	P49841	GSK3B	S187	T183K	183	Missense	distal	-4	no	8.391	7.862	EPSD	ICGC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	Q13131	PRKAA1	P49841	GSK3B	S356	L362I	362	Missense	distal	6	no	10.303	10.308	EPSD	ICGC;COSMIC	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	Q13131	PRKAA1	P49841	GSK3B	S356	A354V	354	Missense	proximal	-2	no	10.303	10.605	EPSD	ICGC;COSMIC	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	Q13131	PRKAA1	P49841	GSK3B	S356	S360F	360	Missense	distal	4	no	10.303	6.689	EPSD	ICGC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	Q13131	PRKAA1	P49841	GSK3B	S356	D350Y	350	Missense	distal	-6	no	10.303	10.242	EPSD	ICGC;COSMIC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	Q13131	PRKAA1	P49841	GSK3B	T482	E480K	480	Missense	proximal	-2	no	6.344	6.313	EPSD	ICGC;COSMIC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	Q13131	PRKAA1	P49841	GSK3B	T482	D479A	479	Missense	distal	-3	no	6.344	6.319	EPSD	ICGC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	Q13131	PRKAA1	P49841	GSK3B	S486	E480K	480	Missense	distal	-6	no	8.478	8.477	EPSD;PhosphoSitePlus	ICGC;COSMIC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	Q13131	PRKAA1	P49841	GSK3B	S486	D479A	479	Missense	distal	-7	no	8.478	8.498	EPSD;PhosphoSitePlus	ICGC	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	Q13131	PRKAA1	P49841	GSK3B	S520	S524Y	524	Missense	distal	4	no	8.064	4.551	EPSD	ICGC;COSMIC	6.007	Loss
CMGC_GSK_GSK3B_ST	Q13131	PRKAA1	P49841	GSK3B	S523	S530C	530	Missense	distal	7	no	5.848	6.240	EPSD	ICGC;COSMIC	6.007	Gain
CMGC_GSK_GSK3B_ST	Q13131	PRKAA1	P49841	GSK3B	S523	S524Y	524	Missense	proximal	1	no	5.848	6.375	EPSD	ICGC;COSMIC	6.007	Gain
CMGC_GSK_GSK3B_ST	Q13131	PRKAA1	P49841	GSK3B	T526	S530C	530	Missense	distal	4	no	6.927	0.794	EPSD	ICGC;COSMIC	6.007	Loss
CMGC_GSK_GSK3B_ST	Q13131	PRKAA1	P49841	GSK3B	T526	S524Y	524	Missense	proximal	-2	no	6.927	6.608	EPSD	ICGC;COSMIC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	Q13131	PRKAA1	P49841	GSK3B	S527	S530C	530	Missense	distal	3	no	7.544	7.329	EPSD	ICGC;COSMIC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	Q13131	PRKAA1	P49841	GSK3B	S527	S524Y	524	Missense	distal	-3	no	7.544	7.684	EPSD	ICGC;COSMIC	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	Q13131	PRKAA1	P49841	GSK3B	S531	S530C	530	Missense	proximal	-1	no	7.665	7.629	EPSD	ICGC;COSMIC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	Q13131	PRKAA1	P49841	GSK3B	S531	S524Y	524	Missense	distal	-7	no	7.665	7.694	EPSD	ICGC;COSMIC	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	P11388	TOP2A	P49841	GSK3B	S4	P8S	8	Missense	distal	4	no	5.425	8.396	EPSD	ICGC;COSMIC	6.007	Gain
CMGC_GSK_GSK3B_ST	P11388	TOP2A	P49841	GSK3B	S802	A801D	801	Missense	proximal	-1	no	7.426	7.520	EPSD	ICGC	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	P11388	TOP2A	P49841	GSK3B	T950	M943T	943	Missense	distal	-7	no	6.650	6.656	EPSD	ICGC	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	P11388	TOP2A	P49841	GSK3B	S1115	G1122E	1122	Missense	distal	7	no	6.522	6.541	EPSD	ICGC;COSMIC	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	P11388	TOP2A	P49841	GSK3B	S1115	E1109K	1109	Missense	distal	-6	no	6.522	6.521	EPSD	ICGC;COSMIC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	P11388	TOP2A	P49841	GSK3B	S1295	S1302I	1302	Missense	distal	7	no	5.831	6.166	EPSD	ICGC	6.007	Gain
CMGC_GSK_GSK3B_ST	P11388	TOP2A	P49841	GSK3B	S1299	S1302I	1302	Missense	distal	3	no	7.051	6.630	EPSD	ICGC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	P11388	TOP2A	P49841	GSK3B	S1351	P1355S	1355	Missense	distal	4	no	5.422	8.393	EPSD	ICGC	6.007	Gain
CMGC_GSK_GSK3B_ST	P11388	TOP2A	P49841	GSK3B	S1354	P1355S	1355	Missense	proximal	1	no	9.605	5.761	EPSD	ICGC	6.007	Loss
CMGC_GSK_GSK3B_ST	P11388	TOP2A	P49841	GSK3B	S1354	P1350T	1350	Missense	distal	-4	no	9.605	9.833	EPSD	ICGC;COSMIC	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	P11388	TOP2A	P49841	GSK3B	S1361	P1355S	1355	Missense	distal	-6	no	10.106	10.085	PhosphoSitePlus	ICGC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	P11388	TOP2A	P49841	GSK3B	S1387	P1394T	1394	Missense	distal	7	no	6.530	6.534	EPSD	ICGC;COSMIC	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	P11388	TOP2A	P49841	GSK3B	S1387	K1385N	1385	Missense	proximal	-2	no	6.530	6.436	EPSD	ICGC;COSMIC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	P11388	TOP2A	P49841	GSK3B	S1391	P1395T	1395	Missense	distal	4	no	4.607	6.709	EPSD	ICGC;COSMIC	6.007	Gain
CMGC_GSK_GSK3B_ST	P11388	TOP2A	P49841	GSK3B	S1393	P1395T	1395	Missense	proximal	2	no	7.378	7.060	EPSD	ICGC;COSMIC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	P11388	TOP2A	P49841	GSK3B	S1393	P1394T	1394	Missense	proximal	1	no	7.378	4.187	EPSD	ICGC;COSMIC	6.007	Loss
CMGC_GSK_GSK3B_ST	P11388	TOP2A	P49841	GSK3B	T1487	K1492N	1492	Missense	distal	5	no	5.993	6.231	EPSD	ICGC;COSMIC	6.007	Gain
CMGC_GSK_GSK3B_ST	P36956	SREBF1	P49841	GSK3B	T59	S63F	63	Missense	distal	4	no	7.415	3.801	EPSD	ICGC;COSMIC	6.007	Loss
CMGC_GSK_GSK3B_ST	P36956	SREBF1	P49841	GSK3B	T59	G58D	58	Missense	proximal	-1	no	7.415	7.348	EPSD	ICGC;COSMIC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	P36956	SREBF1	P49841	GSK3B	T59	G57R	57	Missense	proximal	-2	no	7.415	7.417	EPSD	ICGC;COSMIC	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	P36956	SREBF1	P49841	GSK3B	T59	A62D	62	Missense	distal	3	no	7.415	7.847	EPSD	ICGC	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	P36956	SREBF1	P49841	GSK3B	S63	S63F	63	Missense	central	0	yes	11.097	0.000	EPSD	ICGC;COSMIC	6.007	Loss
CMGC_GSK_GSK3B_ST	P36956	SREBF1	P49841	GSK3B	S63	G58D	58	Missense	distal	-5	no	11.097	10.903	EPSD	ICGC;COSMIC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	P36956	SREBF1	P49841	GSK3B	S63	G57R	57	Missense	distal	-6	no	11.097	11.024	EPSD	ICGC;COSMIC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	P36956	SREBF1	P49841	GSK3B	S63	A62D	62	Missense	proximal	-1	no	11.097	11.192	EPSD	ICGC	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	P36956	SREBF1	P49841	GSK3B	S63	S68P	68	Missense	distal	5	no	11.097	12.051	EPSD	ICGC;COSMIC	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	P36956	SREBF1	P49841	GSK3B	S117	S112F	112	Missense	distal	-5	no	5.680	6.240	EPSD	ICGC	6.007	Gain
CMGC_GSK_GSK3B_ST	P36956	SREBF1	P49841	GSK3B	S117	A115T	115	Missense	proximal	-2	no	5.680	6.042	EPSD	ICGC;COSMIC	6.007	Gain
CMGC_GSK_GSK3B_ST	P10636	MAPT	P49841	GSK3B	T52	P59Q	59	Missense	distal	7	no	5.925	6.078	EPSD	ICGC	6.007	Gain
CMGC_GSK_GSK3B_ST	P10636	MAPT	P49841	GSK3B	S64	P59Q	59	Missense	distal	-5	no	5.721	6.021	EPSD	ICGC	6.007	Gain
CMGC_GSK_GSK3B_ST	P10636	MAPT	P49841	GSK3B	T111	D116E	116	Missense	distal	5	no	8.413	8.616	EPSD	ICGC;COSMIC	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	P10636	MAPT	P49841	GSK3B	T167	P160L	160	Missense	distal	-7	no	7.072	7.074	EPSD	ICGC;COSMIC	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	P10636	MAPT	P49841	GSK3B	T167	R164T	164	Missense	distal	-3	no	7.072	6.928	EPSD	ICGC;COSMIC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	P10636	MAPT	P49841	GSK3B	T167	A166T	166	Missense	proximal	-1	no	7.072	7.152	EPSD	ICGC	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	P10636	MAPT	P49841	GSK3B	S171	R164T	164	Missense	distal	-7	no	6.238	6.247	EPSD	ICGC;COSMIC	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	P10636	MAPT	P49841	GSK3B	S171	A166T	166	Missense	distal	-5	no	6.238	6.250	EPSD	ICGC	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	P10636	MAPT	P49841	GSK3B	S228	P233H	233	Missense	distal	5	no	11.620	9.993	EPSD	ICGC;COSMIC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	P10636	MAPT	P49841	GSK3B	S228	S232F	232	Missense	distal	4	no	11.620	8.006	EPSD	ICGC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	P10636	MAPT	P49841	GSK3B	S228	D225N	225	Missense	distal	-3	no	11.620	11.479	EPSD	ICGC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	P10636	MAPT	P49841	GSK3B	S228	V224I	224	Missense	distal	-4	no	11.620	10.371	EPSD	ICGC;COSMIC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	P10636	MAPT	P49841	GSK3B	S232	P233H	233	Missense	proximal	1	no	6.264	2.564	EPSD	ICGC;COSMIC	6.007	Loss
CMGC_GSK_GSK3B_ST	P10636	MAPT	P49841	GSK3B	S232	S232F	232	Missense	central	0	yes	6.264	0.000	EPSD	ICGC	6.007	Loss
CMGC_GSK_GSK3B_ST	P10636	MAPT	P49841	GSK3B	S232	D225N	225	Missense	distal	-7	no	6.264	6.268	EPSD	ICGC	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	P10636	MAPT	P49841	GSK3B	S232	P239Q	239	Missense	distal	7	no	6.264	6.418	EPSD	ICGC;COSMIC	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	P10636	MAPT	P49841	GSK3B	S238	P233H	233	Missense	distal	-5	no	7.281	7.604	EPSD	ICGC;COSMIC	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	P10636	MAPT	P49841	GSK3B	S238	S232F	232	Missense	distal	-6	no	7.281	7.227	EPSD	ICGC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	P10636	MAPT	P49841	GSK3B	S238	P239Q	239	Missense	proximal	1	no	7.281	4.013	EPSD	ICGC;COSMIC	6.007	Loss
CMGC_GSK_GSK3B_ST	P10636	MAPT	P49841	GSK3B	S438	Y441H	441	Missense	distal	3	no	6.877	7.271	EPSD	ICGC;COSMIC	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	P10636	MAPT	P49841	GSK3B	S447	Y441H	441	Missense	distal	-6	no	9.392	9.444	EPSD	ICGC;COSMIC	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	P10636	MAPT	P49841	GSK3B	S515	G521R	521	Missense	distal	6	no	7.219	7.217	EPSD	ICGC;COSMIC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	P10636	MAPT	P49841	GSK3B	S516	G521R	521	Missense	distal	5	no	7.391	7.665	EPSD	ICGC;COSMIC	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	P10636	MAPT	P49841	GSK3B	S519	G521R	521	Missense	proximal	2	no	7.994	8.270	EPSD	ICGC;COSMIC	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	P10636	MAPT	P49841	GSK3B	T522	G521R	521	Missense	proximal	-1	no	6.333	6.189	EPSD	ICGC;COSMIC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	P10636	MAPT	P49841	GSK3B	S525	G521R	521	Missense	distal	-4	no	8.083	7.324	EPSD	ICGC;COSMIC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	P10636	MAPT	P49841	GSK3B	S527	G521R	521	Missense	distal	-6	no	7.147	7.073	EPSD	ICGC;COSMIC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	Q8N122	RPTOR	P49841	GSK3B	S696	T699M	699	Missense	distal	3	no	7.052	6.893	EPSD	ICGC;COSMIC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	Q8N122	RPTOR	P49841	GSK3B	T706	T699M	699	Missense	distal	-7	no	7.306	7.300	EPSD	ICGC;COSMIC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	Q8N122	RPTOR	P49841	GSK3B	S855	T853M	853	Missense	proximal	-2	no	7.438	7.080	EPSD	ICGC;COSMIC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	Q8N122	RPTOR	P49841	GSK3B	S859	T853M	853	Missense	distal	-6	no	8.586	8.591	PhosphoSitePlus;EPSD	ICGC;COSMIC	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	Q8N122	RPTOR	P49841	GSK3B	S881	S887N	887	Missense	distal	6	no	7.749	7.742	EPSD	ICGC;COSMIC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	Q8N122	RPTOR	P49841	GSK3B	S882	S887N	887	Missense	distal	5	no	6.772	6.451	EPSD	ICGC;COSMIC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	Q8N122	RPTOR	P49841	GSK3B	T917	A914V	914	Missense	distal	-3	no	6.035	6.181	EPSD	ICGC;COSMIC	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	Q13541	EIF4EBP1	P49841	GSK3B	S6	C7S	7	Missense	proximal	1	no	5.806	6.284	EPSD	ICGC;COSMIC	6.007	Gain
CMGC_GSK_GSK3B_ST	Q13541	EIF4EBP1	P49841	GSK3B	S8	C7S	7	Missense	proximal	-1	no	8.311	8.347	EPSD	ICGC;COSMIC	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	Q13541	EIF4EBP1	P49841	GSK3B	T10	C7S	7	Missense	distal	-3	no	6.930	6.827	EPSD	ICGC;COSMIC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	Q13541	EIF4EBP1	P49841	GSK3B	T37	G40V	40	Missense	distal	3	no	10.541	10.290	EPSD;PhosphoSitePlus	ICGC;COSMIC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	Q13541	EIF4EBP1	P49841	GSK3B	T37	S35I	35	Missense	proximal	-2	no	10.541	10.531	EPSD;PhosphoSitePlus	ICGC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	Q13541	EIF4EBP1	P49841	GSK3B	T37	T41S	41	Missense	distal	4	no	10.541	11.410	EPSD;PhosphoSitePlus	ICGC;COSMIC	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	Q13541	EIF4EBP1	P49841	GSK3B	T41	G40V	40	Missense	proximal	-1	no	6.469	6.511	EPSD	ICGC;COSMIC	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	Q13541	EIF4EBP1	P49841	GSK3B	T41	S35I	35	Missense	distal	-6	no	6.469	6.406	EPSD	ICGC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	Q13541	EIF4EBP1	P49841	GSK3B	T46	G40V	40	Missense	distal	-6	no	7.326	7.243	EPSD;PhosphoSitePlus	ICGC;COSMIC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	Q13541	EIF4EBP1	P49841	GSK3B	T46	T41S	41	Missense	distal	-5	no	7.326	7.037	EPSD;PhosphoSitePlus	ICGC;COSMIC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	Q13541	EIF4EBP1	P49841	GSK3B	S65	P71A	71	Missense	distal	6	no	7.228	7.224	PhosphoSitePlus;EPSD	ICGC;COSMIC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	Q13541	EIF4EBP1	P49841	GSK3B	S65	P71H	71	Missense	distal	6	no	7.228	7.216	PhosphoSitePlus;EPSD	ICGC;COSMIC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	Q13541	EIF4EBP1	P49841	GSK3B	S101	S94I	94	Missense	distal	-7	no	6.885	6.913	EPSD	ICGC	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	Q13541	EIF4EBP1	P49841	GSK3B	S101	R106Q	106	Missense	distal	5	no	6.885	6.546	EPSD	ICGC;COSMIC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	Q13541	EIF4EBP1	P49841	GSK3B	S101	G108C	108	Missense	distal	7	no	6.885	7.257	EPSD	ICGC;COSMIC	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	Q13541	EIF4EBP1	P49841	GSK3B	S101	A107T	107	Missense	distal	6	no	6.885	6.889	EPSD	ICGC;COSMIC	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	Q13541	EIF4EBP1	P49841	GSK3B	S101	D104Y	104	Missense	distal	3	no	6.885	6.368	EPSD	ICGC;COSMIC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	Q13541	EIF4EBP1	P49841	GSK3B	S101	H97Q	97	Missense	distal	-4	no	6.885	7.143	EPSD	ICGC;COSMIC	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	Q13541	EIF4EBP1	P49841	GSK3B	S101	S101C	101	Missense	central	0	yes	6.885	0.000	EPSD	ICGC;COSMIC	6.007	Loss
CMGC_GSK_GSK3B_ST	Q15208	STK38	P49841	GSK3B	S6	T4K	4	Missense	proximal	-2	no	7.729	7.568	PhosphoSitePlus;EPSD	ICGC;COSMIC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	Q15208	STK38	P49841	GSK3B	T7	T4K	4	Missense	distal	-3	no	7.295	7.293	EPSD;PhosphoSitePlus	ICGC;COSMIC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	Q15208	STK38	P49841	GSK3B	S281	R276C	276	Missense	distal	-5	no	7.111	6.933	EPSD	ICGC;COSMIC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	Q15208	STK38	P49841	GSK3B	S281	A279D	279	Missense	proximal	-2	no	7.111	7.430	EPSD	ICGC	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	P50895	BCAM	P49841	GSK3B	S206	N199D	199	Missense	distal	-7	no	6.864	6.861	EPSD	ICGC;COSMIC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	P50895	BCAM	P49841	GSK3B	S296	T302M	302	Missense	distal	6	no	6.134	6.126	EPSD	ICGC;COSMIC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	P50895	BCAM	P49841	GSK3B	S296	G293K	293	Missense	distal	-3	no	6.134	6.162	EPSD	ICGC	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	P50895	BCAM	P49841	GSK3B	S296	P299S	299	Missense	distal	3	no	6.134	6.116	EPSD	ICGC;COSMIC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	P50895	BCAM	P49841	GSK3B	S296	D294N	294	Missense	proximal	-2	no	6.134	5.921	EPSD	ICGC	6.007	Loss
CMGC_GSK_GSK3B_ST	P50895	BCAM	P49841	GSK3B	S541	T539A	539	Missense	proximal	-2	no	9.231	8.869	EPSD	ICGC;COSMIC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	P50895	BCAM	P49841	GSK3B	S541	V540M	540	Missense	proximal	-1	no	9.231	9.132	EPSD	ICGC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	P50895	BCAM	P49841	GSK3B	S596	P589L	589	Missense	distal	-7	no	6.700	6.702	PhosphoSitePlus	ICGC;COSMIC;GDSC	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	Q9UPN3	MACF1	P49841	GSK3B	S280	D275N	275	Missense	distal	-5	no	6.510	5.946	EPSD	ICGC	6.007	Loss
CMGC_GSK_GSK3B_ST	Q9UPN3	MACF1	P49841	GSK3B	S559	S560A	560	Missense	proximal	1	no	6.119	6.232	EPSD	ICGC	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	Q9UPN3	MACF1	P49841	GSK3B	S862	R861H	861	Missense	proximal	-1	no	8.019	8.104	EPSD	ICGC;COSMIC	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	Q9UPN3	MACF1	P49841	GSK3B	S862	P863Q	863	Missense	proximal	1	no	8.019	4.750	EPSD	ICGC	6.007	Loss
CMGC_GSK_GSK3B_ST	Q9UPN3	MACF1	P49841	GSK3B	S1122	Q1121H	1121	Missense	proximal	-1	no	10.429	10.484	EPSD	ICGC;COSMIC	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	Q9UPN3	MACF1	P49841	GSK3B	S1363	G1369V	1369	Missense	distal	6	no	7.336	7.329	EPSD	ICGC;COSMIC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	Q9UPN3	MACF1	P49841	GSK3B	S1363	K1366E	1366	Missense	distal	3	no	7.336	7.443	EPSD	ICGC;COSMIC	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	Q9UPN3	MACF1	P49841	GSK3B	S1367	R1372C	1372	Missense	distal	5	no	8.371	6.815	EPSD	ICGC;COSMIC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	Q9UPN3	MACF1	P49841	GSK3B	S1367	G1369V	1369	Missense	proximal	2	no	8.371	8.360	EPSD	ICGC;COSMIC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	Q9UPN3	MACF1	P49841	GSK3B	S1367	R1372L	1372	Missense	distal	5	no	8.371	7.728	EPSD	ICGC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	Q9UPN3	MACF1	P49841	GSK3B	S1367	R1371L	1371	Missense	distal	4	no	8.371	8.691	EPSD	ICGC	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	Q9UPN3	MACF1	P49841	GSK3B	S1367	K1366E	1366	Missense	proximal	-1	no	8.371	8.304	EPSD	ICGC;COSMIC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	Q9UPN3	MACF1	P49841	GSK3B	S1367	R1371C	1371	Missense	distal	4	no	8.371	5.276	EPSD	ICGC;COSMIC	6.007	Loss
CMGC_GSK_GSK3B_ST	Q9UPN3	MACF1	P49841	GSK3B	S1367	R1372H	1372	Missense	distal	5	no	8.371	7.382	EPSD	ICGC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	Q9UPN3	MACF1	P49841	GSK3B	S1744	M1742V	1742	Missense	proximal	-2	no	5.876	6.174	EPSD	ICGC	6.007	Gain
CMGC_GSK_GSK3B_ST	Q9UPN3	MACF1	P49841	GSK3B	S2006	E2012Q	2012	Missense	distal	6	no	7.218	7.220	EPSD	ICGC	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	Q9UPN3	MACF1	P49841	GSK3B	S2006	S1999F	1999	Missense	distal	-7	no	7.218	7.228	EPSD	ICGC;COSMIC	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	Q9UPN3	MACF1	P49841	GSK3B	T2020	E2022Q	2022	Missense	proximal	2	no	7.853	8.163	EPSD	ICGC;COSMIC	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	Q9UPN3	MACF1	P49841	GSK3B	T2020	K2019T	2019	Missense	proximal	-1	no	7.853	7.723	EPSD	ICGC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	Q9UPN3	MACF1	P49841	GSK3B	T2020	H2015R	2015	Missense	distal	-5	no	7.853	8.384	EPSD	ICGC;COSMIC	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	Q9UPN3	MACF1	P49841	GSK3B	S2078	V2072I	2072	Missense	distal	-6	no	6.192	6.197	EPSD	ICGC;COSMIC	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	Q9UPN3	MACF1	P49841	GSK3B	S2078	S2078Y	2078	Missense	central	0	yes	6.192	0.000	EPSD	ICGC	6.007	Loss
CMGC_GSK_GSK3B_ST	Q9UPN3	MACF1	P49841	GSK3B	S2078	D2076G	2076	Missense	proximal	-2	no	6.192	6.090	EPSD	ICGC;COSMIC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	Q9UPN3	MACF1	P49841	GSK3B	S2078	S2077F	2077	Missense	proximal	-1	no	6.192	6.062	EPSD	ICGC;COSMIC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	Q9UPN3	MACF1	P49841	GSK3B	S2078	P2082T	2082	Missense	distal	4	no	6.192	8.295	EPSD	ICGC;COSMIC	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	Q9UPN3	MACF1	P49841	GSK3B	S2078	P2082H	2082	Missense	distal	4	no	6.192	5.407	EPSD	ICGC;COSMIC	6.007	Loss
CMGC_GSK_GSK3B_ST	Q9UPN3	MACF1	P49841	GSK3B	S2157	P2161S	2161	Missense	distal	4	no	3.225	6.196	EPSD	ICGC;COSMIC	6.007	Gain
CMGC_GSK_GSK3B_ST	Q9UPN3	MACF1	P49841	GSK3B	T2160	H2165Q	2165	Missense	distal	5	no	5.408	6.058	EPSD	ICGC	6.007	Gain
CMGC_GSK_GSK3B_ST	Q9UPN3	MACF1	P49841	GSK3B	S3016	P3022H	3022	Missense	distal	6	no	6.795	6.783	EPSD	ICGC;COSMIC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	Q9UPN3	MACF1	P49841	GSK3B	S3016	S3020G	3020	Missense	distal	4	no	6.795	3.552	EPSD	ICGC;COSMIC	6.007	Loss
CMGC_GSK_GSK3B_ST	Q9UPN3	MACF1	P49841	GSK3B	S3331	E3326K	3326	Missense	distal	-5	no	6.051	5.820	EPSD	ICGC;COSMIC	6.007	Loss
CMGC_GSK_GSK3B_ST	Q9UPN3	MACF1	P49841	GSK3B	S3331	P3338L	3338	Missense	distal	7	no	6.051	6.100	EPSD	ICGC;COSMIC	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	Q9UPN3	MACF1	P49841	GSK3B	T3337	T3341I	3341	Missense	distal	4	no	6.384	3.931	EPSD	ICGC	6.007	Loss
CMGC_GSK_GSK3B_ST	Q9UPN3	MACF1	P49841	GSK3B	T3337	E3344Q	3344	Missense	distal	7	no	6.384	6.435	EPSD	ICGC	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	Q9UPN3	MACF1	P49841	GSK3B	T3337	P3338L	3338	Missense	proximal	1	no	6.384	3.524	EPSD	ICGC;COSMIC	6.007	Loss
CMGC_GSK_GSK3B_ST	Q9UPN3	MACF1	P49841	GSK3B	T3337	F3339L	3339	Missense	proximal	2	no	6.384	6.789	EPSD	ICGC;COSMIC	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	Q9UPN3	MACF1	P49841	GSK3B	S3692	R3694L	3694	Missense	proximal	2	no	6.543	6.585	EPSD	ICGC	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	Q9UPN3	MACF1	P49841	GSK3B	S3692	E3686G	3686	Missense	distal	-6	no	6.543	6.621	EPSD	ICGC;CCLE	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	Q9UPN3	MACF1	P49841	GSK3B	S3914	K3910N	3910	Missense	distal	-4	no	6.900	6.467	EPSD	ICGC;COSMIC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	Q9UPN3	MACF1	P49841	GSK3B	S3914	L3921M	3921	Missense	distal	7	no	6.900	7.283	EPSD	ICGC;COSMIC	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	Q9UPN3	MACF1	P49841	GSK3B	S3914	S3914N	3914	Missense	central	0	yes	6.900	0.000	EPSD	ICGC;COSMIC	6.007	Loss
CMGC_GSK_GSK3B_ST	Q9UPN3	MACF1	P49841	GSK3B	S4168	T4172A	4172	Missense	distal	4	no	6.582	5.039	EPSD	ICGC;COSMIC	6.007	Loss
CMGC_GSK_GSK3B_ST	Q9UPN3	MACF1	P49841	GSK3B	S4168	R4173H	4173	Missense	distal	5	no	6.582	5.592	EPSD	ICGC;COSMIC	6.007	Loss
CMGC_GSK_GSK3B_ST	Q9UPN3	MACF1	P49841	GSK3B	S4415	G4410C	4410	Missense	distal	-5	no	7.201	7.254	EPSD	ICGC;COSMIC	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	Q9UPN3	MACF1	P49841	GSK3B	S4415	S4418R	4418	Missense	distal	3	no	7.201	6.830	EPSD	ICGC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	Q9UPN3	MACF1	P49841	GSK3B	S4496	P4497L	4497	Missense	proximal	1	no	9.264	6.403	EPSD	ICGC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	Q9UPN3	MACF1	P49841	GSK3B	S4496	A4493D	4493	Missense	distal	-3	no	9.264	9.290	EPSD	ICGC;COSMIC	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	Q9UPN3	MACF1	P49841	GSK3B	S4496	D4492N	4492	Missense	distal	-4	no	9.264	8.567	EPSD	ICGC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	Q9UPN3	MACF1	P49841	GSK3B	S4496	V4503A	4503	Missense	distal	7	no	9.264	9.186	EPSD	ICGC;COSMIC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	Q9UPN3	MACF1	P49841	GSK3B	S4521	K4528N	4528	Missense	distal	7	no	5.840	6.032	EPSD	ICGC;COSMIC	6.007	Gain
CMGC_GSK_GSK3B_ST	Q9UPN3	MACF1	P49841	GSK3B	S4946	E4944D	4944	Missense	proximal	-2	no	7.048	7.136	EPSD	ICGC;COSMIC	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	Q9UPN3	MACF1	P49841	GSK3B	S4946	K4951N	4951	Missense	distal	5	no	7.048	7.286	EPSD	ICGC	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	Q9UPN3	MACF1	P49841	GSK3B	S5588	P5593L	5593	Missense	distal	5	no	6.548	5.268	EPSD	ICGC	6.007	Loss
CMGC_GSK_GSK3B_ST	Q9UPN3	MACF1	P49841	GSK3B	S5592	P5593L	5593	Missense	proximal	1	no	8.862	6.001	EPSD	ICGC	6.007	Loss
CMGC_GSK_GSK3B_ST	Q9UPN3	MACF1	P49841	GSK3B	S5912	E5908D	5908	Missense	distal	-4	no	7.689	7.686	EPSD	ICGC;COSMIC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	Q9UPN3	MACF1	P49841	GSK3B	S5912	R5915H	5915	Missense	distal	3	no	7.689	8.031	EPSD	ICGC;COSMIC;CCLE	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	Q9UPN3	MACF1	P49841	GSK3B	S5912	L5910H	5910	Missense	proximal	-2	no	7.689	7.658	EPSD	ICGC;COSMIC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	Q9UPN3	MACF1	P49841	GSK3B	S6032	G6034D	6034	Missense	proximal	2	no	8.387	8.737	EPSD	ICGC	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	Q9UPN3	MACF1	P49841	GSK3B	S6032	P6037L	6037	Missense	distal	5	no	8.387	7.106	EPSD	ICGC;COSMIC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	Q9UPN3	MACF1	P49841	GSK3B	S6032	D6025Y	6025	Missense	distal	-7	no	8.387	8.413	EPSD	ICGC	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	Q9UPN3	MACF1	P49841	GSK3B	S6032	S6038F	6038	Missense	distal	6	no	8.387	8.375	EPSD	ICGC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	Q9UPN3	MACF1	P49841	GSK3B	S6032	D6025N	6025	Missense	distal	-7	no	8.387	8.390	EPSD	ICGC;COSMIC	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	Q9UPN3	MACF1	P49841	GSK3B	S6402	D6405G	6405	Missense	distal	3	no	7.456	7.405	EPSD	ICGC;COSMIC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	Q9UPN3	MACF1	P49841	GSK3B	S6402	S6402I	6402	Missense	central	0	yes	7.456	0.000	EPSD	ICGC	6.007	Loss
CMGC_GSK_GSK3B_ST	Q9UPN3	MACF1	P49841	GSK3B	S6402	S6406C	6406	Missense	distal	4	no	7.456	1.324	EPSD	ICGC;COSMIC	6.007	Loss
CMGC_GSK_GSK3B_ST	Q9UPN3	MACF1	P49841	GSK3B	S6406	K6411N	6411	Missense	distal	5	no	7.020	7.258	EPSD	ICGC;COSMIC	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	Q9UPN3	MACF1	P49841	GSK3B	S6406	D6405G	6405	Missense	proximal	-1	no	7.020	7.087	EPSD	ICGC;COSMIC	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	Q9UPN3	MACF1	P49841	GSK3B	S6406	S6402I	6402	Missense	distal	-4	no	7.020	4.537	EPSD	ICGC	6.007	Loss
CMGC_GSK_GSK3B_ST	Q9UPN3	MACF1	P49841	GSK3B	S6406	S6402T	6402	Missense	distal	-4	no	7.020	6.684	EPSD	ICGC;COSMIC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	Q9UPN3	MACF1	P49841	GSK3B	S6406	S6406C	6406	Missense	central	0	yes	7.020	0.000	EPSD	ICGC;COSMIC	6.007	Loss
CMGC_GSK_GSK3B_ST	Q9UPN3	MACF1	P49841	GSK3B	S6408	K6411N	6411	Missense	distal	3	no	7.106	7.280	EPSD	ICGC;COSMIC	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	Q9UPN3	MACF1	P49841	GSK3B	S6408	D6405G	6405	Missense	distal	-3	no	7.106	7.055	EPSD	ICGC;COSMIC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	Q9UPN3	MACF1	P49841	GSK3B	S6408	S6402I	6402	Missense	distal	-6	no	7.106	7.043	EPSD	ICGC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	Q9UPN3	MACF1	P49841	GSK3B	S6408	S6402T	6402	Missense	distal	-6	no	7.106	7.048	EPSD	ICGC;COSMIC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	Q9UPN3	MACF1	P49841	GSK3B	S6408	S6406C	6406	Missense	proximal	-2	no	7.106	6.794	EPSD	ICGC;COSMIC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	Q9UPN3	MACF1	P49841	GSK3B	S6732	E6730D	6730	Missense	proximal	-2	no	8.072	8.160	EPSD	ICGC;COSMIC	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	Q9UPN3	MACF1	P49841	GSK3B	S6732	R6733Q	6733	Missense	proximal	1	no	8.072	7.124	EPSD	ICGC;COSMIC;CCLE	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	Q9UPN3	MACF1	P49841	GSK3B	S6732	W6738L	6738	Missense	distal	6	no	8.072	8.083	EPSD	ICGC	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	Q9UPN3	MACF1	P49841	GSK3B	S6732	N6731K	6731	Missense	proximal	-1	no	8.072	8.066	EPSD	ICGC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	Q9UPN3	MACF1	P49841	GSK3B	S7209	S7209C	7209	Missense	central	0	yes	6.491	0.000	EPSD	ICGC;COSMIC	6.007	Loss
CMGC_GSK_GSK3B_ST	Q9UPN3	MACF1	P49841	GSK3B	S7209	E7206D	7206	Missense	distal	-3	no	6.491	6.524	EPSD	ICGC;COSMIC	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	Q9UPN3	MACF1	P49841	GSK3B	S7209	G7207D	7207	Missense	proximal	-2	no	6.491	6.593	EPSD	ICGC;COSMIC	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	Q9UPN3	MACF1	P49841	GSK3B	T7213	S7209C	7209	Missense	distal	-4	no	9.462	7.347	EPSD	ICGC;COSMIC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	Q9UPN3	MACF1	P49841	GSK3B	T7213	E7206D	7206	Missense	distal	-7	no	9.462	9.432	EPSD	ICGC;COSMIC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	Q9UPN3	MACF1	P49841	GSK3B	T7213	G7219C	7219	Missense	distal	6	no	9.462	9.452	EPSD	ICGC;COSMIC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	Q9UPN3	MACF1	P49841	GSK3B	T7213	G7207D	7207	Missense	distal	-6	no	9.462	9.420	EPSD	ICGC;COSMIC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	Q9UPN3	MACF1	P49841	GSK3B	S7226	R7233C	7233	Missense	distal	7	no	8.824	8.778	EPSD;PhosphoSitePlus	ICGC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	Q9UPN3	MACF1	P49841	GSK3B	S7226	G7219C	7219	Missense	distal	-7	no	8.824	8.849	EPSD;PhosphoSitePlus	ICGC;COSMIC	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	Q9UPN3	MACF1	P49841	GSK3B	S7226	P7224L	7224	Missense	proximal	-2	no	8.824	8.494	EPSD;PhosphoSitePlus	ICGC;COSMIC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	Q9UPN3	MACF1	P49841	GSK3B	S7226	S7222F	7222	Missense	distal	-4	no	8.824	7.670	EPSD;PhosphoSitePlus	ICGC;COSMIC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	Q9UPN3	MACF1	P49841	GSK3B	S7230	R7233C	7233	Missense	distal	3	no	9.895	10.050	EPSD;PhosphoSitePlus	ICGC	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	Q9UPN3	MACF1	P49841	GSK3B	S7230	S7235I	7235	Missense	distal	5	no	9.895	9.228	EPSD;PhosphoSitePlus	ICGC;COSMIC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	Q9UPN3	MACF1	P49841	GSK3B	S7230	P7224L	7224	Missense	distal	-6	no	9.895	9.873	EPSD;PhosphoSitePlus	ICGC;COSMIC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	Q9UPN3	MACF1	P49841	GSK3B	S7247	M7248L	7248	Missense	proximal	1	no	6.704	7.430	EPSD	ICGC;COSMIC	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	Q9UPN3	MACF1	P49841	GSK3B	S7247	S7251F	7251	Missense	distal	4	no	6.704	3.089	EPSD	ICGC;COSMIC;CCLE	6.007	Loss
CMGC_GSK_GSK3B_ST	Q9UPN3	MACF1	P49841	GSK3B	S7247	S7244T	7244	Missense	distal	-3	no	6.704	6.728	EPSD	ICGC;COSMIC	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	Q9UPN3	MACF1	P49841	GSK3B	S7251	M7248L	7248	Missense	distal	-3	no	7.910	7.948	EPSD	ICGC;COSMIC	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	Q9UPN3	MACF1	P49841	GSK3B	S7251	S7251F	7251	Missense	central	0	yes	7.910	0.000	EPSD	ICGC;COSMIC;CCLE	6.007	Loss
CMGC_GSK_GSK3B_ST	Q9UPN3	MACF1	P49841	GSK3B	S7251	P7255T	7255	Missense	distal	4	no	7.910	10.013	EPSD	ICGC;COSMIC	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	Q9UPN3	MACF1	P49841	GSK3B	S7251	S7244T	7244	Missense	distal	-7	no	7.910	7.937	EPSD	ICGC;COSMIC	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	Q9UPN3	MACF1	P49841	GSK3B	T7254	M7248L	7248	Missense	distal	-6	no	6.672	6.724	EPSD	ICGC;COSMIC	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	Q9UPN3	MACF1	P49841	GSK3B	T7254	S7251F	7251	Missense	distal	-3	no	6.672	6.739	EPSD	ICGC;COSMIC;CCLE	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	Q9UPN3	MACF1	P49841	GSK3B	T7254	P7255T	7255	Missense	proximal	1	no	6.672	3.481	EPSD	ICGC;COSMIC	6.007	Loss
CMGC_GSK_GSK3B_ST	Q9UPN3	MACF1	P49841	GSK3B	S7288	L7283F	7283	Missense	distal	-5	no	6.117	6.568	EPSD	ICGC;COSMIC	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	Q9UPN3	MACF1	P49841	GSK3B	S7310	S7314N	7314	Missense	distal	4	no	8.655	5.045	EPSD;PhosphoSitePlus	ICGC;COSMIC	6.007	Loss
CMGC_GSK_GSK3B_ST	Q9UPN3	MACF1	P49841	GSK3B	S7310	G7317W	7317	Missense	distal	7	no	8.655	9.182	EPSD;PhosphoSitePlus	ICGC	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	Q9UPN3	MACF1	P49841	GSK3B	S7310	S7310I	7310	Missense	central	0	yes	8.655	0.000	EPSD;PhosphoSitePlus	ICGC;COSMIC	6.007	Loss
CMGC_GSK_GSK3B_ST	Q9UPN3	MACF1	P49841	GSK3B	S7314	S7314N	7314	Missense	central	0	yes	10.462	0.000	EPSD;PhosphoSitePlus	ICGC;COSMIC	6.007	Loss
CMGC_GSK_GSK3B_ST	Q9UPN3	MACF1	P49841	GSK3B	S7314	R7319Q	7319	Missense	distal	5	no	10.462	10.124	EPSD;PhosphoSitePlus	ICGC;COSMIC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	Q9UPN3	MACF1	P49841	GSK3B	S7314	G7317W	7317	Missense	distal	3	no	10.462	10.307	EPSD;PhosphoSitePlus	ICGC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	Q9UPN3	MACF1	P49841	GSK3B	S7314	S7310I	7310	Missense	distal	-4	no	10.462	7.979	EPSD;PhosphoSitePlus	ICGC;COSMIC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	Q9UPN3	MACF1	P49841	GSK3B	S7318	S7314N	7314	Missense	distal	-4	no	8.526	7.228	EPSD;PhosphoSitePlus	ICGC;COSMIC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	Q9UPN3	MACF1	P49841	GSK3B	S7318	R7319Q	7319	Missense	proximal	1	no	8.526	7.577	EPSD;PhosphoSitePlus	ICGC;COSMIC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	Q9UPN3	MACF1	P49841	GSK3B	S7318	G7317W	7317	Missense	proximal	-1	no	8.526	8.493	EPSD;PhosphoSitePlus	ICGC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	Q9UPN3	MACF1	P49841	GSK3B	S7322	R7319Q	7319	Missense	distal	-3	no	9.022	8.883	EPSD;PhosphoSitePlus	ICGC;COSMIC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	Q9UPN3	MACF1	P49841	GSK3B	S7322	G7317W	7317	Missense	distal	-5	no	9.022	8.997	EPSD;PhosphoSitePlus	ICGC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	Q9UPN3	MACF1	P49841	GSK3B	S7326	R7319Q	7319	Missense	distal	-7	no	7.358	7.354	EPSD;PhosphoSitePlus	ICGC;COSMIC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	Q9UPN3	MACF1	P49841	GSK3B	S7326	R7328L	7328	Missense	proximal	2	no	7.358	7.399	EPSD;PhosphoSitePlus	ICGC;COSMIC	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	Q9UPN3	MACF1	P49841	GSK3B	S7326	A7332T	7332	Missense	distal	6	no	7.358	7.361	EPSD;PhosphoSitePlus	ICGC	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	Q00653	NFKB2	P49841	GSK3B	S222	Q215E	215	Missense	distal	-7	no	9.574	9.591	EPSD;PhosphoSitePlus	ICGC	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	Q00653	NFKB2	P49841	GSK3B	T429	R428S	428	Missense	proximal	-1	no	8.729	8.866	EPSD	ICGC;COSMIC	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	Q00653	NFKB2	P49841	GSK3B	S711	S715L	715	Missense	distal	4	no	7.797	5.079	PhosphoSitePlus;EPSD	ICGC	6.007	Loss
CMGC_GSK_GSK3B_ST	Q00653	NFKB2	P49841	GSK3B	S713	G719E	719	Missense	distal	6	no	7.328	7.325	EPSD	ICGC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	Q00653	NFKB2	P49841	GSK3B	S713	S715L	715	Missense	proximal	2	no	7.328	7.388	EPSD	ICGC	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	Q00653	NFKB2	P49841	GSK3B	S715	G719E	719	Missense	distal	4	no	5.215	6.438	EPSD	ICGC	6.007	Gain
CMGC_GSK_GSK3B_ST	Q00653	NFKB2	P49841	GSK3B	T732	R725Q	725	Missense	distal	-7	no	6.277	6.274	EPSD	ICGC;COSMIC;GDSC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	Q00653	NFKB2	P49841	GSK3B	T732	G730V	730	Missense	proximal	-2	no	6.277	6.362	EPSD	ICGC	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	Q00653	NFKB2	P49841	GSK3B	T759	P766Q	766	Missense	distal	7	no	6.142	6.295	EPSD	ICGC;COSMIC	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	Q00653	NFKB2	P49841	GSK3B	T759	P766L	766	Missense	distal	7	no	6.142	6.191	EPSD	ICGC;COSMIC	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	Q00653	NFKB2	P49841	GSK3B	S762	P766Q	766	Missense	distal	4	no	6.370	5.778	EPSD	ICGC;COSMIC	6.007	Loss
CMGC_GSK_GSK3B_ST	Q00653	NFKB2	P49841	GSK3B	S762	P766L	766	Missense	distal	4	no	6.370	6.624	EPSD	ICGC;COSMIC	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	Q00653	NFKB2	P49841	GSK3B	S769	P766Q	766	Missense	distal	-3	no	7.028	7.175	EPSD	ICGC;COSMIC	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	Q00653	NFKB2	P49841	GSK3B	S769	P766L	766	Missense	distal	-3	no	7.028	7.154	EPSD	ICGC;COSMIC	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	Q00653	NFKB2	P49841	GSK3B	T806	T806K	806	Missense	central	0	yes	7.451	0.000	EPSD	ICGC;COSMIC	6.007	Loss
CMGC_GSK_GSK3B_ST	Q00653	NFKB2	P49841	GSK3B	T806	R808Q	808	Missense	proximal	2	no	7.451	7.656	EPSD	ICGC	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	Q00653	NFKB2	P49841	GSK3B	T810	T806K	806	Missense	distal	-4	no	6.596	6.067	EPSD	ICGC;COSMIC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	Q00653	NFKB2	P49841	GSK3B	T810	R808Q	808	Missense	proximal	-2	no	6.596	6.667	EPSD	ICGC	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	Q00653	NFKB2	P49841	GSK3B	S812	T806K	806	Missense	distal	-6	no	10.832	10.827	EPSD	ICGC;COSMIC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	Q00653	NFKB2	P49841	GSK3B	S812	R808Q	808	Missense	distal	-4	no	10.832	11.189	EPSD	ICGC	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	Q00653	NFKB2	P49841	GSK3B	S814	R808Q	808	Missense	distal	-6	no	6.181	6.234	EPSD	ICGC	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	P58012	FOXL2	P49841	GSK3B	S33	K36N	36	Missense	distal	3	no	7.625	7.800	PhosphoSitePlus	ICGC;COSMIC	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	P58012	FOXL2	P49841	GSK3B	S211	P214S	214	Missense	distal	3	no	7.140	7.122	EPSD	ICGC;COSMIC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	P58012	FOXL2	P49841	GSK3B	S211	S217Y	217	Missense	distal	6	no	7.140	7.134	EPSD	ICGC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	P58012	FOXL2	P49841	GSK3B	S238	A241T	241	Missense	distal	3	no	7.385	7.689	EPSD	ICGC;COSMIC	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	P58012	FOXL2	P49841	GSK3B	S323	A325D	325	Missense	proximal	2	no	8.251	8.335	EPSD	ICGC;COSMIC	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	P58012	FOXL2	P49841	GSK3B	S323	P319S	319	Missense	distal	-4	no	8.251	8.814	EPSD	ICGC;COSMIC	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	P58012	FOXL2	P49841	GSK3B	S326	A325D	325	Missense	proximal	-1	no	7.202	7.296	EPSD	ICGC;COSMIC	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	P58012	FOXL2	P49841	GSK3B	S326	P319S	319	Missense	distal	-7	no	7.202	7.204	EPSD	ICGC;COSMIC	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	O15294	OGT	P49841	GSK3B	S1004	P1005T	1005	Missense	proximal	1	no	7.036	3.845	EPSD	ICGC;COSMIC;GDSC;CCLE	6.007	Loss
CMGC_GSK_GSK3B_ST	Q14449	GRB14	P49841	GSK3B	S362	P367H	367	Missense	distal	5	no	8.428	6.801	PhosphoSitePlus;EPSD	ICGC;COSMIC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	Q14449	GRB14	P49841	GSK3B	S362	M368I	368	Missense	distal	6	no	8.428	8.433	PhosphoSitePlus;EPSD	ICGC;COSMIC	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	Q14449	GRB14	P49841	GSK3B	S366	P367H	367	Missense	proximal	1	no	9.293	5.592	EPSD;PhosphoSitePlus	ICGC;COSMIC	6.007	Loss
CMGC_GSK_GSK3B_ST	Q14449	GRB14	P49841	GSK3B	S366	M368I	368	Missense	proximal	2	no	9.293	9.924	EPSD;PhosphoSitePlus	ICGC;COSMIC	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	P49768	PSEN1	P49841	GSK3B	S59	V62L	62	Missense	distal	3	no	6.466	6.374	EPSD	ICGC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	P49768	PSEN1	P49841	GSK3B	S59	Q56K	56	Missense	distal	-3	no	6.466	6.460	EPSD	ICGC;COSMIC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	O75122	CLASP2	P49841	GSK3B	S21	D16N	16	Missense	distal	-5	no	6.655	6.091	EPSD	ICGC;COSMIC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	O75122	CLASP2	P49841	GSK3B	S364	S370R	370	Missense	distal	6	no	8.449	8.445	EPSD	ICGC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	O75122	CLASP2	P49841	GSK3B	S368	S370R	370	Missense	proximal	2	no	6.078	6.097	EPSD	ICGC	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	O75122	CLASP2	P49841	GSK3B	S517	R521H	521	Missense	distal	4	no	6.946	6.228	EPSD	ICGC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	O75122	CLASP2	P49841	GSK3B	S517	R521C	521	Missense	distal	4	no	6.946	3.851	EPSD	ICGC	6.007	Loss
CMGC_GSK_GSK3B_ST	O75122	CLASP2	P49841	GSK3B	S525	R521H	521	Missense	distal	-4	no	6.757	6.856	EPSD	ICGC	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	O75122	CLASP2	P49841	GSK3B	S525	R521C	521	Missense	distal	-4	no	6.757	5.829	EPSD	ICGC	6.007	Loss
CMGC_GSK_GSK3B_ST	Q6PGQ7	BORA	P49841	GSK3B	S112	T105I	105	Missense	distal	-7	no	7.110	7.111	EPSD	ICGC	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	Q6PGQ7	BORA	P49841	GSK3B	S112	V108F	108	Missense	distal	-4	no	7.110	7.190	EPSD	ICGC	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	Q6PGQ7	BORA	P49841	GSK3B	S112	D116V	116	Missense	distal	4	no	7.110	7.144	EPSD	ICGC	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	Q6PGQ7	BORA	P49841	GSK3B	S112	D116Y	116	Missense	distal	4	no	7.110	6.021	EPSD	ICGC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	Q6PGQ7	BORA	P49841	GSK3B	S135	T131S	131	Missense	distal	-4	no	6.129	6.465	EPSD	ICGC	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	Q6PGQ7	BORA	P49841	GSK3B	S135	N132Y	132	Missense	distal	-3	no	6.129	6.364	EPSD	ICGC	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	Q6PGQ7	BORA	P49841	GSK3B	S183	S189Y	189	Missense	distal	6	no	6.500	6.494	EPSD	ICGC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	Q6PGQ7	BORA	P49841	GSK3B	S183	E178G	178	Missense	distal	-5	no	6.500	6.535	EPSD	ICGC	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	Q6PGQ7	BORA	P49841	GSK3B	S229	L232F	232	Missense	distal	3	no	6.354	6.443	EPSD	ICGC	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	Q6PGQ7	BORA	P49841	GSK3B	S239	L232F	232	Missense	distal	-7	no	9.646	9.656	EPSD	ICGC	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	Q6PGQ7	BORA	P49841	GSK3B	T243	S250Y	250	Missense	distal	7	no	7.362	7.804	EPSD	ICGC	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	Q6PGQ7	BORA	P49841	GSK3B	T243	G247V	247	Missense	distal	4	no	7.362	8.215	EPSD	ICGC	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	Q6PGQ7	BORA	P49841	GSK3B	S246	S250Y	250	Missense	distal	4	no	6.360	2.847	EPSD	ICGC	6.007	Loss
CMGC_GSK_GSK3B_ST	Q6PGQ7	BORA	P49841	GSK3B	S246	G247V	247	Missense	proximal	1	no	6.360	6.563	EPSD	ICGC	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	Q6PGQ7	BORA	P49841	GSK3B	S246	S252N	252	Missense	distal	6	no	6.360	6.353	EPSD	ICGC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	Q6PGQ7	BORA	P49841	GSK3B	S252	S250Y	250	Missense	proximal	-2	no	7.365	7.045	EPSD	ICGC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	Q6PGQ7	BORA	P49841	GSK3B	S252	G247V	247	Missense	distal	-5	no	7.365	7.478	EPSD	ICGC	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	Q6PGQ7	BORA	P49841	GSK3B	S252	S252N	252	Missense	central	0	yes	7.365	0.000	EPSD	ICGC	6.007	Loss
CMGC_GSK_GSK3B_ST	Q6PGQ7	BORA	P49841	GSK3B	S268	S262R	262	Missense	distal	-6	no	6.184	6.127	EPSD	ICGC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	Q6PGQ7	BORA	P49841	GSK3B	S497	I493T	493	Missense	distal	-4	no	4.297	6.445	EPSD	ICGC	6.007	Gain
CMGC_GSK_GSK3B_ST	O95863	SNAI1	P49841	GSK3B	S82	R78W	78	Missense	distal	-4	no	6.302	5.472	EPSD	ICGC;COSMIC	6.007	Loss
CMGC_GSK_GSK3B_ST	O95863	SNAI1	P49841	GSK3B	S92	L88M	88	Missense	distal	-4	no	6.352	6.643	EPSD	ICGC	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	O95863	SNAI1	P49841	GSK3B	S107	S112F	112	Missense	distal	5	no	11.906	11.239	EPSD;PhosphoSitePlus	ICGC;COSMIC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	O95863	SNAI1	P49841	GSK3B	S111	V118A	118	Missense	distal	7	no	6.721	6.643	EPSD;PhosphoSitePlus	ICGC;COSMIC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	O95863	SNAI1	P49841	GSK3B	S111	S112F	112	Missense	proximal	1	no	6.721	6.334	EPSD;PhosphoSitePlus	ICGC;COSMIC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	O95863	SNAI1	P49841	GSK3B	S115	V118A	118	Missense	distal	3	no	6.986	6.857	EPSD;PhosphoSitePlus	ICGC;COSMIC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	O95863	SNAI1	P49841	GSK3B	S115	S112F	112	Missense	distal	-3	no	6.986	7.053	EPSD;PhosphoSitePlus	ICGC;COSMIC	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	P19793	RXRA	P49841	GSK3B	S17	T23M	23	Missense	distal	6	no	7.134	7.127	EPSD	ICGC;COSMIC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	P19793	RXRA	P49841	GSK3B	S17	D10Y	10	Missense	distal	-7	no	7.134	7.160	EPSD	ICGC	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	P19793	RXRA	P49841	GSK3B	S21	T23M	23	Missense	proximal	2	no	6.940	6.242	EPSD	ICGC;COSMIC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	P19793	RXRA	P49841	GSK3B	S49	G42V	42	Missense	distal	-7	no	9.069	9.092	PhosphoSitePlus;EPSD	ICGC;COSMIC	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	P19793	RXRA	P49841	GSK3B	S260	P258H	258	Missense	proximal	-2	no	6.299	5.937	EPSD	ICGC;COSMIC	6.007	Loss
CMGC_GSK_GSK3B_ST	P05412	JUN	P49841	GSK3B	S63	K70T	70	Missense	distal	7	no	6.218	6.229	EPSD	ICGC;COSMIC	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	P05412	JUN	P49841	GSK3B	S73	A72E	72	Missense	proximal	-1	no	7.671	7.814	EPSD	ICGC;COSMIC	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	P05412	JUN	P49841	GSK3B	S73	K70T	70	Missense	distal	-3	no	7.671	7.672	EPSD	ICGC;COSMIC	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	P05412	JUN	P49841	GSK3B	T91	T93N	93	Missense	proximal	2	no	8.831	8.173	EPSD	ICGC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	P05412	JUN	P49841	GSK3B	T91	L98R	98	Missense	distal	7	no	8.831	9.283	EPSD	ICGC	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	P05412	JUN	P49841	GSK3B	T93	T93N	93	Missense	central	0	yes	6.874	0.000	EPSD	ICGC	6.007	Loss
CMGC_GSK_GSK3B_ST	P05412	JUN	P49841	GSK3B	T93	L98R	98	Missense	distal	5	no	6.874	7.517	EPSD	ICGC	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	P05412	JUN	P49841	GSK3B	T231	A224V	224	Missense	distal	-7	no	7.587	7.585	EPSD	ICGC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	P05412	JUN	P49841	GSK3B	T239	T239K	239	Missense	central	0	yes	10.446	0.000	EPSD;PhosphoSitePlus	ICGC	6.007	Loss
CMGC_GSK_GSK3B_ST	P05412	JUN	P49841	GSK3B	S243	T239K	239	Missense	distal	-4	no	8.558	8.029	PhosphoSitePlus;EPSD	ICGC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	Q9UMX1	SUFU	P49841	GSK3B	T13	A14P	14	Missense	proximal	1	no	4.491	8.223	EPSD	ICGC;COSMIC	6.007	Gain
CMGC_GSK_GSK3B_ST	Q9UMX1	SUFU	P49841	GSK3B	S342	S342N	342	Missense	central	0	yes	7.675	0.000	PhosphoSitePlus	ICGC;COSMIC	6.007	Loss
CMGC_GSK_GSK3B_ST	Q9UMX1	SUFU	P49841	GSK3B	S342	A340S	340	Missense	proximal	-2	no	7.675	8.010	PhosphoSitePlus	ICGC;COSMIC	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	Q9UMX1	SUFU	P49841	GSK3B	S342	A336T	336	Missense	distal	-6	no	7.675	7.607	PhosphoSitePlus	ICGC;COSMIC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	Q9UMX1	SUFU	P49841	GSK3B	S342	R339P	339	Missense	distal	-3	no	7.675	7.390	PhosphoSitePlus	ICGC;COSMIC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	Q9UMX1	SUFU	P49841	GSK3B	S342	L335R	335	Missense	distal	-7	no	7.675	7.694	PhosphoSitePlus	ICGC;COSMIC	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	Q9UMX1	SUFU	P49841	GSK3B	S349	S342N	342	Missense	distal	-7	no	6.655	6.661	EPSD	ICGC;COSMIC	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	O00213	APBB1	P49841	GSK3B	S175	L173P	173	Missense	proximal	-2	no	8.911	9.241	EPSD	ICGC;COSMIC	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	O00213	APBB1	P49841	GSK3B	S175	P176H	176	Missense	proximal	1	no	8.911	5.210	EPSD	ICGC;COSMIC	6.007	Loss
CMGC_GSK_GSK3B_ST	P03372	ESR1	P49841	GSK3B	S102	P99S	99	Missense	distal	-3	no	9.469	9.586	PhosphoSitePlus;EPSD	ICGC	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	P03372	ESR1	P49841	GSK3B	S102	G95W	95	Missense	distal	-7	no	9.469	9.499	PhosphoSitePlus;EPSD	ICGC	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	P03372	ESR1	P49841	GSK3B	S102	S102N	102	Missense	central	0	yes	9.469	0.000	PhosphoSitePlus;EPSD	ICGC;COSMIC	6.007	Loss
CMGC_GSK_GSK3B_ST	P03372	ESR1	P49841	GSK3B	S102	N101S	101	Missense	proximal	-1	no	9.469	9.408	PhosphoSitePlus;EPSD	ICGC;COSMIC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	P03372	ESR1	P49841	GSK3B	S106	P99S	99	Missense	distal	-7	no	9.203	9.204	EPSD;PhosphoSitePlus	ICGC	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	P03372	ESR1	P49841	GSK3B	S106	S102N	102	Missense	distal	-4	no	9.203	7.905	EPSD;PhosphoSitePlus	ICGC;COSMIC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	P03372	ESR1	P49841	GSK3B	S106	N101S	101	Missense	distal	-5	no	9.203	9.495	EPSD;PhosphoSitePlus	ICGC;COSMIC	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	P03372	ESR1	P49841	GSK3B	S106	H112P	112	Missense	distal	6	no	9.203	9.214	EPSD;PhosphoSitePlus	ICGC;COSMIC	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	P03372	ESR1	P49841	GSK3B	S282	A283V	283	Missense	proximal	1	no	5.345	6.087	EPSD	ICGC;COSMIC	6.007	Gain
CMGC_GSK_GSK3B_ST	P03372	ESR1	P49841	GSK3B	S305	K302T	302	Missense	distal	-3	no	6.457	6.459	EPSD	ICGC;COSMIC	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	P03372	ESR1	P49841	GSK3B	S305	R300L	300	Missense	distal	-5	no	6.457	5.869	EPSD	ICGC;COSMIC	6.007	Loss
CMGC_GSK_GSK3B_ST	P03372	ESR1	P49841	GSK3B	S305	R300S	300	Missense	distal	-5	no	6.457	5.760	EPSD	ICGC;COSMIC	6.007	Loss
CMGC_GSK_GSK3B_ST	P03372	ESR1	P49841	GSK3B	S305	R300H	300	Missense	distal	-5	no	6.457	5.927	EPSD	ICGC;COSMIC	6.007	Loss
CMGC_GSK_GSK3B_ST	P03372	ESR1	P49841	GSK3B	T570	S576L	576	Missense	distal	6	no	6.049	6.044	EPSD	ICGC;COSMIC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	O95271	TNKS	P49841	GSK3B	S218	D211N	211	Missense	distal	-7	no	6.668	6.671	EPSD	ICGC;COSMIC	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	O95271	TNKS	P49841	GSK3B	S218	A223S	223	Missense	distal	5	no	6.668	6.742	EPSD	ICGC;COSMIC	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	O95271	TNKS	P49841	GSK3B	T477	A475S	475	Missense	proximal	-2	no	6.547	6.882	EPSD	ICGC;COSMIC	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	O95271	TNKS	P49841	GSK3B	T477	A471S	471	Missense	distal	-6	no	6.547	6.536	EPSD	ICGC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	O95271	TNKS	P49841	GSK3B	T477	P478L	478	Missense	proximal	1	no	6.547	3.686	EPSD	ICGC;COSMIC	6.007	Loss
CMGC_GSK_GSK3B_ST	O95271	TNKS	P49841	GSK3B	S978	C985F	985	Missense	distal	7	no	9.811	9.497	EPSD;PhosphoSitePlus	ICGC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	O95271	TNKS	P49841	GSK3B	T982	C985F	985	Missense	distal	3	no	8.175	8.180	PhosphoSitePlus;EPSD	ICGC	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	Q9NS23	RASSF1	P49841	GSK3B	T43	R36W	36	Missense	distal	-7	no	6.775	6.785	EPSD	ICGC	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	Q9NS23	RASSF1	P49841	GSK3B	T43	N41T	41	Missense	proximal	-2	no	6.775	7.031	EPSD	ICGC	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	O75925	PIAS1	P49841	GSK3B	S483	R479G	479	Missense	distal	-4	no	5.344	6.103	EPSD	ICGC;COSMIC	6.007	Gain
CMGC_GSK_GSK3B_ST	O75925	PIAS1	P49841	GSK3B	S503	R507S	507	Missense	distal	4	no	5.575	8.613	EPSD	ICGC;COSMIC	6.007	Gain
CMGC_GSK_GSK3B_ST	O75925	PIAS1	P49841	GSK3B	S506	A513V	513	Missense	distal	7	no	7.611	7.688	EPSD	ICGC	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	O75925	PIAS1	P49841	GSK3B	S506	A502S	502	Missense	distal	-4	no	7.611	8.771	EPSD	ICGC	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	O75925	PIAS1	P49841	GSK3B	S506	R507S	507	Missense	proximal	1	no	7.611	6.086	EPSD	ICGC;COSMIC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	O75925	PIAS1	P49841	GSK3B	S510	A513V	513	Missense	distal	3	no	6.945	7.074	EPSD	ICGC	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	O75925	PIAS1	P49841	GSK3B	S510	V514L	514	Missense	distal	4	no	6.945	6.617	EPSD	ICGC;COSMIC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	O75925	PIAS1	P49841	GSK3B	S510	R507S	507	Missense	distal	-3	no	6.945	6.777	EPSD	ICGC;COSMIC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	O75925	PIAS1	P49841	GSK3B	S517	I519M	519	Missense	proximal	2	no	6.679	6.047	EPSD	ICGC;COSMIC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	O75925	PIAS1	P49841	GSK3B	S517	A513V	513	Missense	distal	-4	no	6.679	6.605	EPSD	ICGC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	O75925	PIAS1	P49841	GSK3B	S517	V514L	514	Missense	distal	-3	no	6.679	6.521	EPSD	ICGC;COSMIC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	Q8NHW3	MAFA	P49841	GSK3B	S49	S56N	56	Missense	distal	7	no	8.896	9.019	EPSD;PhosphoSitePlus	ICGC;COSMIC	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	Q8NHW3	MAFA	P49841	GSK3B	S49	S52L	52	Missense	distal	3	no	8.896	8.595	EPSD;PhosphoSitePlus	ICGC;COSMIC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	Q8NHW3	MAFA	P49841	GSK3B	T53	S56N	56	Missense	distal	3	no	11.257	11.305	EPSD;PhosphoSitePlus	ICGC;COSMIC	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	Q8NHW3	MAFA	P49841	GSK3B	T53	S52L	52	Missense	proximal	-1	no	11.257	11.182	EPSD;PhosphoSitePlus	ICGC;COSMIC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	Q8NHW3	MAFA	P49841	GSK3B	T57	S56N	56	Missense	proximal	-1	no	9.242	9.304	EPSD;PhosphoSitePlus	ICGC;COSMIC	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	Q8NHW3	MAFA	P49841	GSK3B	T57	S52L	52	Missense	distal	-5	no	9.242	9.351	EPSD;PhosphoSitePlus	ICGC;COSMIC	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	Q8NHW3	MAFA	P49841	GSK3B	S61	S56N	56	Missense	distal	-5	no	9.476	9.184	PhosphoSitePlus;EPSD	ICGC;COSMIC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	Q14596	NBR1	P49841	GSK3B	S123	V120I	120	Missense	distal	-3	no	7.385	7.331	EPSD	ICGC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	Q14596	NBR1	P49841	GSK3B	T277	P281S	281	Missense	distal	4	no	5.072	8.043	EPSD	ICGC;COSMIC	6.007	Gain
CMGC_GSK_GSK3B_ST	Q14596	NBR1	P49841	GSK3B	T581	H579Y	579	Missense	proximal	-2	no	6.430	6.217	EPSD	ICGC;COSMIC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	Q14596	NBR1	P49841	GSK3B	T581	V585L	585	Missense	distal	4	no	6.430	6.103	EPSD	ICGC;COSMIC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	Q14596	NBR1	P49841	GSK3B	T581	P582T	582	Missense	proximal	1	no	6.430	3.239	EPSD	ICGC;COSMIC	6.007	Loss
CMGC_GSK_GSK3B_ST	Q14596	NBR1	P49841	GSK3B	T581	P578S	578	Missense	distal	-3	no	6.430	6.547	EPSD	ICGC;COSMIC	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	Q14596	NBR1	P49841	GSK3B	T586	H579Y	579	Missense	distal	-7	no	10.220	10.230	PhosphoSitePlus	ICGC;COSMIC	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	Q14596	NBR1	P49841	GSK3B	T586	V585L	585	Missense	proximal	-1	no	10.220	10.096	PhosphoSitePlus	ICGC;COSMIC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	Q14596	NBR1	P49841	GSK3B	T586	P582T	582	Missense	distal	-4	no	10.220	10.448	PhosphoSitePlus	ICGC;COSMIC	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	Q14596	NBR1	P49841	GSK3B	S590	V585L	585	Missense	distal	-5	no	6.747	6.276	EPSD	ICGC;COSMIC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	Q14596	NBR1	P49841	GSK3B	S833	P826S	826	Missense	distal	-7	no	9.121	9.122	EPSD	ICGC	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	Q14596	NBR1	P49841	GSK3B	S833	P839Q	839	Missense	distal	6	no	9.121	9.115	EPSD	ICGC;COSMIC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	Q14596	NBR1	P49841	GSK3B	T841	P839Q	839	Missense	proximal	-2	no	6.065	5.764	EPSD	ICGC;COSMIC	6.007	Loss
CMGC_GSK_GSK3B_ST	Q14596	NBR1	P49841	GSK3B	S891	K898N	898	Missense	distal	7	no	6.696	6.889	EPSD	ICGC;COSMIC	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	P12036	NEFH	P49841	GSK3B	T53	S49T	49	Missense	distal	-4	no	6.175	5.840	EPSD	ICGC;COSMIC	6.007	Loss
CMGC_GSK_GSK3B_ST	P12036	NEFH	P49841	GSK3B	T53	T53M	53	Missense	central	0	yes	6.175	0.000	EPSD	ICGC;COSMIC	6.007	Loss
CMGC_GSK_GSK3B_ST	P12036	NEFH	P49841	GSK3B	S57	R64C	64	Missense	distal	7	no	7.937	7.891	EPSD	ICGC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	P12036	NEFH	P49841	GSK3B	S57	R64L	64	Missense	distal	7	no	7.937	7.484	EPSD	ICGC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	P12036	NEFH	P49841	GSK3B	S57	T53M	53	Missense	distal	-4	no	7.937	7.212	EPSD	ICGC;COSMIC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	P12036	NEFH	P49841	GSK3B	S59	R64C	64	Missense	distal	5	no	6.913	5.357	EPSD	ICGC	6.007	Loss
CMGC_GSK_GSK3B_ST	P12036	NEFH	P49841	GSK3B	S59	R64L	64	Missense	distal	5	no	6.913	6.270	EPSD	ICGC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	P12036	NEFH	P49841	GSK3B	S59	T53M	53	Missense	distal	-6	no	6.913	6.918	EPSD	ICGC;COSMIC	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	P12036	NEFH	P49841	GSK3B	S61	R64C	64	Missense	distal	3	no	6.829	6.984	EPSD	ICGC	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	P12036	NEFH	P49841	GSK3B	S61	R64L	64	Missense	distal	3	no	6.829	6.899	EPSD	ICGC	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	P12036	NEFH	P49841	GSK3B	S72	A70T	70	Missense	proximal	-2	no	5.723	6.084	EPSD	ICGC;COSMIC	6.007	Gain
CMGC_GSK_GSK3B_ST	P12036	NEFH	P49841	GSK3B	S503	G496W	496	Missense	distal	-7	no	9.470	9.500	PhosphoSitePlus	ICGC;COSMIC	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	P12036	NEFH	P49841	GSK3B	S518	A524E	524	Missense	distal	6	no	7.766	7.762	EPSD	ICGC;COSMIC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	P12036	NEFH	P49841	GSK3B	S518	K521N	521	Missense	distal	3	no	7.766	7.940	EPSD	ICGC;COSMIC	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	P12036	NEFH	P49841	GSK3B	S518	E523D	523	Missense	distal	5	no	7.766	7.563	EPSD	ICGC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	P12036	NEFH	P49841	GSK3B	S532	P527L	527	Missense	distal	-5	no	7.606	7.871	EPSD	ICGC;COSMIC	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	P12036	NEFH	P49841	GSK3B	S552	P547T	547	Missense	distal	-5	no	7.707	8.153	EPSD	ICGC;COSMIC	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	P12036	NEFH	P49841	GSK3B	S552	P553Q	553	Missense	proximal	1	no	7.707	4.439	EPSD	ICGC;COSMIC	6.007	Loss
CMGC_GSK_GSK3B_ST	P12036	NEFH	P49841	GSK3B	S566	P561L	561	Missense	distal	-5	no	8.311	8.577	EPSD	ICGC;COSMIC;GDSC;CCLE	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	P12036	NEFH	P49841	GSK3B	S566	P562A	562	Missense	distal	-4	no	8.311	7.715	EPSD	ICGC;COSMIC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	P12036	NEFH	P49841	GSK3B	S586	A588V	588	Missense	proximal	2	no	7.938	7.661	EPSD	ICGC;COSMIC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	P12036	NEFH	P49841	GSK3B	S594	P595L	595	Missense	proximal	1	no	6.174	3.313	EPSD	ICGC	6.007	Loss
CMGC_GSK_GSK3B_ST	P12036	NEFH	P49841	GSK3B	S594	A588V	588	Missense	distal	-6	no	6.174	6.096	EPSD	ICGC;COSMIC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	P12036	NEFH	P49841	GSK3B	S600	K603N	603	Missense	distal	3	no	5.884	6.059	EPSD	ICGC	6.007	Gain
CMGC_GSK_GSK3B_ST	P12036	NEFH	P49841	GSK3B	S600	P595L	595	Missense	distal	-5	no	5.884	6.150	EPSD	ICGC	6.007	Gain
CMGC_GSK_GSK3B_ST	P12036	NEFH	P49841	GSK3B	S606	K603N	603	Missense	distal	-3	no	7.430	7.311	EPSD	ICGC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	P12036	NEFH	P49841	GSK3B	S620	P615L	615	Missense	distal	-5	no	6.904	7.169	EPSD	ICGC;COSMIC	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	P12036	NEFH	P49841	GSK3B	S620	S620F	620	Missense	central	0	yes	6.904	0.000	EPSD	ICGC;COSMIC	6.007	Loss
CMGC_GSK_GSK3B_ST	P12036	NEFH	P49841	GSK3B	S640	P641L	641	Missense	proximal	1	no	7.717	4.857	EPSD	ICGC;COSMIC	6.007	Loss
CMGC_GSK_GSK3B_ST	P12036	NEFH	P49841	GSK3B	S640	E645K	645	Missense	distal	5	no	7.717	6.850	EPSD	ICGC;COSMIC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	P12036	NEFH	P49841	GSK3B	S654	E656V	656	Missense	proximal	2	no	6.622	6.440	EPSD	ICGC;COSMIC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	P12036	NEFH	P49841	GSK3B	S660	E656V	656	Missense	distal	-4	no	7.222	6.586	EPSD	ICGC;COSMIC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	P12036	NEFH	P49841	GSK3B	S668	A672E	672	Missense	distal	4	no	6.532	6.923	EPSD	ICGC;COSMIC	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	P12036	NEFH	P49841	GSK3B	S674	A672E	672	Missense	proximal	-2	no	6.934	7.166	EPSD	ICGC;COSMIC	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	P12036	NEFH	P49841	GSK3B	S682	A686E	686	Missense	distal	4	no	5.858	6.249	EPSD	ICGC;COSMIC	6.007	Gain
CMGC_GSK_GSK3B_ST	P12036	NEFH	P49841	GSK3B	S688	A686E	686	Missense	proximal	-2	no	6.665	6.897	EPSD	ICGC;COSMIC	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	P12036	NEFH	P49841	GSK3B	S724	P725Q	725	Missense	proximal	1	no	6.324	3.056	EPSD	ICGC;COSMIC	6.007	Loss
CMGC_GSK_GSK3B_ST	P12036	NEFH	P49841	GSK3B	S730	P725Q	725	Missense	distal	-5	no	7.365	7.664	EPSD	ICGC;COSMIC	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	P12036	NEFH	P49841	GSK3B	S744	E748V	748	Missense	distal	4	no	7.026	6.657	EPSD	ICGC;COSMIC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	P12036	NEFH	P49841	GSK3B	S807	S801Y	801	Missense	distal	-6	no	7.675	7.589	EPSD	ICGC;COSMIC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	O00429	DNM1L	P49841	GSK3B	S40	K38N	38	Missense	proximal	-2	no	8.819	8.725	PhosphoSitePlus;EPSD	ICGC;COSMIC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	O00429	DNM1L	P49841	GSK3B	S44	K38N	38	Missense	distal	-6	no	6.165	6.226	EPSD;PhosphoSitePlus	ICGC;COSMIC	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	O00429	DNM1L	P49841	GSK3B	T189	A196T	196	Missense	distal	7	no	6.090	5.683	EPSD	ICGC;COSMIC	6.007	Loss
CMGC_GSK_GSK3B_ST	O00429	DNM1L	P49841	GSK3B	S544	A539S	539	Missense	distal	-5	no	6.419	6.142	EPSD	ICGC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	O00429	DNM1L	P49841	GSK3B	S544	A541S	541	Missense	distal	-3	no	6.419	6.398	EPSD	ICGC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	O00429	DNM1L	P49841	GSK3B	S544	S548F	548	Missense	distal	4	no	6.419	2.805	EPSD	ICGC;COSMIC	6.007	Loss
CMGC_GSK_GSK3B_ST	O00429	DNM1L	P49841	GSK3B	S544	S548Y	548	Missense	distal	4	no	6.419	2.906	EPSD	ICGC;COSMIC	6.007	Loss
CMGC_GSK_GSK3B_ST	O00429	DNM1L	P49841	GSK3B	S548	A541S	541	Missense	distal	-7	no	10.349	10.327	EPSD	ICGC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	O00429	DNM1L	P49841	GSK3B	S548	S548F	548	Missense	central	0	yes	10.349	0.000	EPSD	ICGC;COSMIC	6.007	Loss
CMGC_GSK_GSK3B_ST	O00429	DNM1L	P49841	GSK3B	S548	A553T	553	Missense	distal	5	no	10.349	10.401	EPSD	ICGC	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	O00429	DNM1L	P49841	GSK3B	S548	A553V	553	Missense	distal	5	no	10.349	9.923	EPSD	ICGC;COSMIC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	O00429	DNM1L	P49841	GSK3B	S548	S548Y	548	Missense	central	0	yes	10.349	0.000	EPSD	ICGC;COSMIC	6.007	Loss
CMGC_GSK_GSK3B_ST	Q92908	GATA6	P49841	GSK3B	S33	A26S	26	Missense	distal	-7	no	6.374	6.351	EPSD	ICGC;COSMIC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	Q92908	GATA6	P49841	GSK3B	S33	P38T	38	Missense	distal	5	no	6.374	5.397	EPSD	ICGC;COSMIC	6.007	Loss
CMGC_GSK_GSK3B_ST	Q92908	GATA6	P49841	GSK3B	S33	P38H	38	Missense	distal	5	no	6.374	4.747	EPSD	ICGC;COSMIC	6.007	Loss
CMGC_GSK_GSK3B_ST	Q92908	GATA6	P49841	GSK3B	T34	P38T	38	Missense	distal	4	no	5.862	7.965	EPSD	ICGC;COSMIC	6.007	Gain
CMGC_GSK_GSK3B_ST	Q92908	GATA6	P49841	GSK3B	S37	P38T	38	Missense	proximal	1	no	10.924	7.733	PhosphoSitePlus	ICGC;COSMIC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	Q92908	GATA6	P49841	GSK3B	S37	P38H	38	Missense	proximal	1	no	10.924	7.224	PhosphoSitePlus	ICGC;COSMIC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	Q92908	GATA6	P49841	GSK3B	S41	S45C	45	Missense	distal	4	no	6.029	-0.103	EPSD	ICGC;COSMIC	6.007	Loss
CMGC_GSK_GSK3B_ST	Q92908	GATA6	P49841	GSK3B	S41	P38T	38	Missense	distal	-3	no	6.029	6.171	EPSD	ICGC;COSMIC	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	Q92908	GATA6	P49841	GSK3B	S41	P38H	38	Missense	distal	-3	no	6.029	6.258	EPSD	ICGC;COSMIC	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	Q92908	GATA6	P49841	GSK3B	T62	A57T	57	Missense	distal	-5	no	8.268	8.280	EPSD	ICGC	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	Q92908	GATA6	P49841	GSK3B	S266	A261E	261	Missense	distal	-5	no	7.513	7.666	EPSD	ICGC;COSMIC	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	Q92908	GATA6	P49841	GSK3B	S266	A261V	261	Missense	distal	-5	no	7.513	7.815	EPSD	ICGC	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	Q92908	GATA6	P49841	GSK3B	S266	A272S	272	Missense	distal	6	no	7.513	7.515	EPSD	ICGC;COSMIC	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	Q92908	GATA6	P49841	GSK3B	S268	A261E	261	Missense	distal	-7	no	8.810	8.820	EPSD	ICGC;COSMIC	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	Q92908	GATA6	P49841	GSK3B	S268	A261V	261	Missense	distal	-7	no	8.810	8.809	EPSD	ICGC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	Q92908	GATA6	P49841	GSK3B	S268	A272S	272	Missense	distal	4	no	8.810	11.221	EPSD	ICGC;COSMIC	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	Q92908	GATA6	P49841	GSK3B	T515	I512T	512	Missense	distal	-3	no	8.408	8.320	EPSD	ICGC;COSMIC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	Q92908	GATA6	P49841	GSK3B	T515	M514I	514	Missense	proximal	-1	no	8.408	8.309	EPSD	ICGC;COSMIC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	Q92908	GATA6	P49841	GSK3B	T515	T517A	517	Missense	proximal	2	no	8.408	8.290	EPSD	ICGC;COSMIC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	Q92908	GATA6	P49841	GSK3B	S523	D525N	525	Missense	proximal	2	no	6.520	5.896	EPSD	ICGC;COSMIC	6.007	Loss
CMGC_GSK_GSK3B_ST	Q92908	GATA6	P49841	GSK3B	S523	T517A	517	Missense	distal	-6	no	6.520	6.589	EPSD	ICGC;COSMIC	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	Q92908	GATA6	P49841	GSK3B	S531	D525N	525	Missense	distal	-6	no	8.241	8.264	EPSD	ICGC;COSMIC	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	Q92908	GATA6	P49841	GSK3B	T537	A541S	541	Missense	distal	4	no	4.890	7.302	EPSD	ICGC;COSMIC	6.007	Gain
CMGC_GSK_GSK3B_ST	P17275	JUNB	P49841	GSK3B	S70	S70A	70	Missense	central	0	yes	8.426	0.000	EPSD	ICGC;COSMIC	6.007	Loss
CMGC_GSK_GSK3B_ST	P17275	JUNB	P49841	GSK3B	S70	G77S	77	Missense	distal	7	no	8.426	8.407	EPSD	ICGC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	P17275	JUNB	P49841	GSK3B	S70	S67T	67	Missense	distal	-3	no	8.426	8.451	EPSD	ICGC	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	P17275	JUNB	P49841	GSK3B	T102	Q108H	108	Missense	distal	6	no	7.614	7.608	EPSD	ICGC;COSMIC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	P17275	JUNB	P49841	GSK3B	S251	D253E	253	Missense	proximal	2	no	9.767	9.587	EPSD;PhosphoSitePlus	ICGC;COSMIC;CCLE	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	P17275	JUNB	P49841	GSK3B	T255	P260L	260	Missense	distal	5	no	12.175	10.895	PhosphoSitePlus;EPSD	ICGC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	P17275	JUNB	P49841	GSK3B	T255	D253E	253	Missense	proximal	-2	no	12.175	12.088	PhosphoSitePlus;EPSD	ICGC;COSMIC;CCLE	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	P17275	JUNB	P49841	GSK3B	S259	Q266R	266	Missense	distal	7	no	8.319	8.667	EPSD	ICGC;COSMIC	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	P17275	JUNB	P49841	GSK3B	S259	P260L	260	Missense	proximal	1	no	8.319	5.458	EPSD	ICGC	6.007	Loss
CMGC_GSK_GSK3B_ST	P17275	JUNB	P49841	GSK3B	S259	D253E	253	Missense	distal	-6	no	8.319	8.282	EPSD	ICGC;COSMIC;CCLE	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	P30304	CDC25A	P49841	GSK3B	S88	S88F	88	Missense	central	0	yes	6.665	0.000	EPSD	ICGC;COSMIC	6.007	Loss
CMGC_GSK_GSK3B_ST	P30304	CDC25A	P49841	GSK3B	S88	D93E	93	Missense	distal	5	no	6.665	6.868	EPSD	ICGC	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	P30304	CDC25A	P49841	GSK3B	S116	P117Q	117	Missense	proximal	1	no	6.284	3.016	EPSD	ICGC	6.007	Loss
CMGC_GSK_GSK3B_ST	P30304	CDC25A	P49841	GSK3B	S122	P117Q	117	Missense	distal	-5	no	5.822	6.121	EPSD	ICGC	6.007	Gain
CMGC_GSK_GSK3B_ST	P30304	CDC25A	P49841	GSK3B	S263	S263F	263	Missense	central	0	yes	6.869	0.000	EPSD	ICGC	6.007	Loss
CMGC_GSK_GSK3B_ST	P30304	CDC25A	P49841	GSK3B	S279	P285H	285	Missense	distal	6	no	6.111	6.099	EPSD	ICGC;COSMIC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	P30304	CDC25A	P49841	GSK3B	S283	P285H	285	Missense	proximal	2	no	10.746	9.977	EPSD	ICGC;COSMIC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	P30304	CDC25A	P49841	GSK3B	S298	T303A	303	Missense	distal	5	no	8.655	8.603	EPSD	ICGC;COSMIC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	P30304	CDC25A	P49841	GSK3B	S317	S317Y	317	Missense	central	0	yes	7.549	0.000	EPSD	ICGC	6.007	Loss
CMGC_GSK_GSK3B_ST	P30304	CDC25A	P49841	GSK3B	S317	S315Y	315	Missense	proximal	-2	no	7.549	7.229	EPSD	ICGC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	P30304	CDC25A	P49841	GSK3B	S317	A319E	319	Missense	proximal	2	no	7.549	7.454	EPSD	ICGC;COSMIC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	P30304	CDC25A	P49841	GSK3B	S317	G324R	324	Missense	distal	7	no	7.549	7.967	EPSD	ICGC	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	P30304	CDC25A	P49841	GSK3B	S321	S317Y	317	Missense	distal	-4	no	7.617	6.817	EPSD	ICGC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	P30304	CDC25A	P49841	GSK3B	S321	S315Y	315	Missense	distal	-6	no	7.617	7.531	EPSD	ICGC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	P30304	CDC25A	P49841	GSK3B	S321	A319E	319	Missense	proximal	-2	no	7.617	7.849	EPSD	ICGC;COSMIC	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	P30304	CDC25A	P49841	GSK3B	S321	G324R	324	Missense	distal	3	no	7.617	7.202	EPSD	ICGC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	P30304	CDC25A	P49841	GSK3B	S505	R506Q	506	Missense	proximal	1	no	6.134	5.185	EPSD	ICGC;COSMIC	6.007	Loss
CMGC_GSK_GSK3B_ST	P30304	CDC25A	P49841	GSK3B	S505	R502C	502	Missense	distal	-3	no	6.134	6.069	EPSD	ICGC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	Q9NRR4	DROSHA	P49841	GSK3B	S217	P216T	216	Missense	proximal	-1	no	6.119	5.987	EPSD	ICGC;COSMIC	6.007	Loss
CMGC_GSK_GSK3B_ST	Q9NRR4	DROSHA	P49841	GSK3B	S221	P216T	216	Missense	distal	-5	no	7.086	7.532	EPSD	ICGC;COSMIC	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	Q9NRR4	DROSHA	P49841	GSK3B	T274	R279S	279	Missense	distal	5	no	8.231	7.914	EPSD	ICGC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	Q9NRR4	DROSHA	P49841	GSK3B	T274	R271Q	271	Missense	distal	-3	no	8.231	8.092	EPSD	ICGC;COSMIC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	Q9NRR4	DROSHA	P49841	GSK3B	S276	R279S	279	Missense	distal	3	no	8.553	8.924	EPSD	ICGC	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	Q9NRR4	DROSHA	P49841	GSK3B	S276	R271Q	271	Missense	distal	-5	no	8.553	7.998	EPSD	ICGC;COSMIC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	Q9NRR4	DROSHA	P49841	GSK3B	S284	R287Q	287	Missense	distal	3	no	6.751	7.085	EPSD	ICGC;COSMIC	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	Q9NRR4	DROSHA	P49841	GSK3B	S284	R279S	279	Missense	distal	-5	no	6.751	6.054	EPSD	ICGC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	Q9NRR4	DROSHA	P49841	GSK3B	S300	S300L	300	Missense	central	0	yes	9.866	0.000	EPSD;PhosphoSitePlus	ICGC;COSMIC	6.007	Loss
CMGC_GSK_GSK3B_ST	Q9NRR4	DROSHA	P49841	GSK3B	S300	N297K	297	Missense	distal	-3	no	9.866	9.984	EPSD;PhosphoSitePlus	ICGC	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	Q9NRR4	DROSHA	P49841	GSK3B	T330	G328V	328	Missense	proximal	-2	no	6.832	6.917	EPSD	ICGC;COSMIC	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	Q9NRR4	DROSHA	P49841	GSK3B	S355	P356Q	356	Missense	proximal	1	no	6.501	3.233	EPSD	ICGC	6.007	Loss
CMGC_GSK_GSK3B_ST	Q9NRR4	DROSHA	P49841	GSK3B	S355	H353N	353	Missense	proximal	-2	no	6.501	6.377	EPSD	ICGC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	Q9NRR4	DROSHA	P49841	GSK3B	S373	S377I	377	Missense	distal	4	no	6.783	3.461	EPSD	ICGC;COSMIC	6.007	Loss
CMGC_GSK_GSK3B_ST	Q9NRR4	DROSHA	P49841	GSK3B	S373	N375I	375	Missense	proximal	2	no	6.783	7.376	EPSD	ICGC;COSMIC	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	Q9NRR4	DROSHA	P49841	GSK3B	S491	S495I	495	Missense	distal	4	no	7.852	4.530	EPSD	ICGC	6.007	Loss
CMGC_GSK_GSK3B_ST	Q9NRR4	DROSHA	P49841	GSK3B	T958	R951C	951	Missense	distal	-7	no	6.513	6.517	EPSD	ICGC;COSMIC	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	Q9NRR4	DROSHA	P49841	GSK3B	S1293	H1294L	1294	Missense	proximal	1	no	5.829	6.668	EPSD	ICGC;COSMIC	6.007	Gain
CMGC_GSK_GSK3B_ST	P15924	DSP	P49841	GSK3B	T59	G60C	60	Missense	proximal	1	no	7.837	6.708	EPSD	ICGC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	P15924	DSP	P49841	GSK3B	S157	A164S	164	Missense	distal	7	no	6.169	5.822	EPSD	ICGC;COSMIC	6.007	Loss
CMGC_GSK_GSK3B_ST	P15924	DSP	P49841	GSK3B	T634	Q631H	631	Missense	distal	-3	no	6.647	6.729	EPSD	ICGC	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	P15924	DSP	P49841	GSK3B	S1303	A1307S	1307	Missense	distal	4	no	3.940	6.351	EPSD	ICGC	6.007	Gain
CMGC_GSK_GSK3B_ST	P15924	DSP	P49841	GSK3B	T1415	R1411S	1411	Missense	distal	-4	no	5.008	6.195	EPSD	ICGC	6.007	Gain
CMGC_GSK_GSK3B_ST	P15924	DSP	P49841	GSK3B	S2024	A2019T	2019	Missense	distal	-5	no	7.352	7.364	EPSD	ICGC;COSMIC	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	P15924	DSP	P49841	GSK3B	S2041	S2041N	2041	Missense	central	0	yes	8.396	0.000	EPSD	ICGC;COSMIC	6.007	Loss
CMGC_GSK_GSK3B_ST	P15924	DSP	P49841	GSK3B	S2549	S2553I	2553	Missense	distal	4	no	6.507	3.185	EPSD	ICGC	6.007	Loss
CMGC_GSK_GSK3B_ST	P15924	DSP	P49841	GSK3B	S2549	L2554F	2554	Missense	distal	5	no	6.507	6.167	EPSD	ICGC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	P15924	DSP	P49841	GSK3B	S2551	S2553I	2553	Missense	proximal	2	no	6.406	6.466	EPSD	ICGC	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	P15924	DSP	P49841	GSK3B	S2551	L2554F	2554	Missense	distal	3	no	6.406	6.495	EPSD	ICGC	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	P15924	DSP	P49841	GSK3B	S2594	K2592E	2592	Missense	proximal	-2	no	6.223	6.255	EPSD	ICGC	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	P15924	DSP	P49841	GSK3B	S2594	S2598R	2598	Missense	distal	4	no	6.223	3.186	EPSD	ICGC	6.007	Loss
CMGC_GSK_GSK3B_ST	P15924	DSP	P49841	GSK3B	S2598	K2592E	2592	Missense	distal	-6	no	6.965	6.966	EPSD	ICGC	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	P15924	DSP	P49841	GSK3B	S2598	S2598R	2598	Missense	central	0	yes	6.965	0.000	EPSD	ICGC	6.007	Loss
CMGC_GSK_GSK3B_ST	P15924	DSP	P49841	GSK3B	T2612	T2612I	2612	Missense	central	0	yes	7.690	0.000	EPSD	ICGC	6.007	Loss
CMGC_GSK_GSK3B_ST	P15924	DSP	P49841	GSK3B	T2612	S2617T	2617	Missense	distal	5	no	7.690	7.667	EPSD	ICGC;COSMIC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	P15924	DSP	P49841	GSK3B	S2617	T2612I	2612	Missense	distal	-5	no	6.490	6.674	EPSD	ICGC	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	P15924	DSP	P49841	GSK3B	S2815	S2815I	2815	Missense	central	0	yes	9.199	0.000	EPSD	ICGC;COSMIC	6.007	Loss
CMGC_GSK_GSK3B_ST	P15924	DSP	P49841	GSK3B	S2815	P2814H	2814	Missense	proximal	-1	no	9.199	9.091	EPSD	ICGC;COSMIC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	P15924	DSP	P49841	GSK3B	S2815	A2822S	2822	Missense	distal	7	no	9.199	8.852	EPSD	ICGC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	P15924	DSP	P49841	GSK3B	S2815	S2809L	2809	Missense	distal	-6	no	9.199	9.198	EPSD	ICGC;COSMIC;GDSC;CCLE	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	P15924	DSP	P49841	GSK3B	S2815	A2822T	2822	Missense	distal	7	no	9.199	8.792	EPSD	ICGC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	P15924	DSP	P49841	GSK3B	S2815	G2812D	2812	Missense	distal	-3	no	9.199	9.249	EPSD	ICGC	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	P15924	DSP	P49841	GSK3B	S2821	S2815I	2815	Missense	distal	-6	no	7.158	7.095	EPSD	ICGC;COSMIC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	P15924	DSP	P49841	GSK3B	S2821	G2828S	2828	Missense	distal	7	no	7.158	7.138	EPSD	ICGC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	P15924	DSP	P49841	GSK3B	S2821	P2814H	2814	Missense	distal	-7	no	7.158	7.178	EPSD	ICGC;COSMIC	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	P15924	DSP	P49841	GSK3B	S2821	A2822S	2822	Missense	proximal	1	no	7.158	7.045	EPSD	ICGC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	P15924	DSP	P49841	GSK3B	S2821	A2822T	2822	Missense	proximal	1	no	7.158	7.699	EPSD	ICGC	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	P15924	DSP	P49841	GSK3B	S2825	G2828S	2828	Missense	distal	3	no	9.505	9.462	EPSD	ICGC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	P15924	DSP	P49841	GSK3B	S2825	S2829F	2829	Missense	distal	4	no	9.505	5.891	EPSD	ICGC	6.007	Loss
CMGC_GSK_GSK3B_ST	P15924	DSP	P49841	GSK3B	S2825	A2822S	2822	Missense	distal	-3	no	9.505	9.485	EPSD	ICGC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	P15924	DSP	P49841	GSK3B	S2825	A2822T	2822	Missense	distal	-3	no	9.505	9.510	EPSD	ICGC	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	P15924	DSP	P49841	GSK3B	S2825	G2832E	2832	Missense	distal	7	no	9.505	9.525	EPSD	ICGC	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	P15924	DSP	P49841	GSK3B	S2827	R2834H	2834	Missense	distal	7	no	7.990	8.178	EPSD	ICGC;COSMIC;GDSC;CCLE	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	P15924	DSP	P49841	GSK3B	S2827	G2828S	2828	Missense	proximal	1	no	7.990	7.340	EPSD	ICGC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	P15924	DSP	P49841	GSK3B	S2827	S2829F	2829	Missense	proximal	2	no	7.990	7.646	EPSD	ICGC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	P15924	DSP	P49841	GSK3B	S2827	R2834L	2834	Missense	distal	7	no	7.990	7.538	EPSD	ICGC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	P15924	DSP	P49841	GSK3B	S2827	A2822S	2822	Missense	distal	-5	no	7.990	7.713	EPSD	ICGC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	P15924	DSP	P49841	GSK3B	S2827	A2822T	2822	Missense	distal	-5	no	7.990	8.002	EPSD	ICGC	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	P15924	DSP	P49841	GSK3B	S2827	G2832E	2832	Missense	distal	5	no	7.990	8.257	EPSD	ICGC	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	P15924	DSP	P49841	GSK3B	S2829	R2834H	2834	Missense	distal	5	no	10.627	9.638	EPSD	ICGC;COSMIC;GDSC;CCLE	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	P15924	DSP	P49841	GSK3B	S2829	G2828S	2828	Missense	proximal	-1	no	10.627	10.620	EPSD	ICGC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	P15924	DSP	P49841	GSK3B	S2829	S2829F	2829	Missense	central	0	yes	10.627	0.000	EPSD	ICGC	6.007	Loss
CMGC_GSK_GSK3B_ST	P15924	DSP	P49841	GSK3B	S2829	R2834L	2834	Missense	distal	5	no	10.627	9.984	EPSD	ICGC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	P15924	DSP	P49841	GSK3B	S2829	A2822S	2822	Missense	distal	-7	no	10.627	10.605	EPSD	ICGC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	P15924	DSP	P49841	GSK3B	S2829	A2822T	2822	Missense	distal	-7	no	10.627	10.632	EPSD	ICGC	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	P15924	DSP	P49841	GSK3B	S2829	G2832E	2832	Missense	distal	3	no	10.627	10.564	EPSD	ICGC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	P15924	DSP	P49841	GSK3B	S2831	R2834H	2834	Missense	distal	3	no	7.617	7.959	EPSD	ICGC;COSMIC;GDSC;CCLE	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	P15924	DSP	P49841	GSK3B	S2831	G2828S	2828	Missense	distal	-3	no	7.617	7.621	EPSD	ICGC	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	P15924	DSP	P49841	GSK3B	S2831	S2829F	2829	Missense	proximal	-2	no	7.617	7.286	EPSD	ICGC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	P15924	DSP	P49841	GSK3B	S2831	S2837Y	2837	Missense	distal	6	no	7.617	7.611	EPSD	ICGC;COSMIC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	P15924	DSP	P49841	GSK3B	S2831	R2834L	2834	Missense	distal	3	no	7.617	7.687	EPSD	ICGC	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	P15924	DSP	P49841	GSK3B	S2831	G2832E	2832	Missense	proximal	1	no	7.617	6.977	EPSD	ICGC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	P15924	DSP	P49841	GSK3B	S2833	R2834H	2834	Missense	proximal	1	no	9.890	8.509	EPSD	ICGC;COSMIC;GDSC;CCLE	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	P15924	DSP	P49841	GSK3B	S2833	G2828S	2828	Missense	distal	-5	no	9.890	9.424	EPSD	ICGC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	P15924	DSP	P49841	GSK3B	S2833	S2829F	2829	Missense	distal	-4	no	9.890	8.736	EPSD	ICGC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	P15924	DSP	P49841	GSK3B	S2833	S2837Y	2837	Missense	distal	4	no	9.890	6.377	EPSD	ICGC;COSMIC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	P15924	DSP	P49841	GSK3B	S2833	R2834L	2834	Missense	proximal	1	no	9.890	9.349	EPSD	ICGC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	P15924	DSP	P49841	GSK3B	S2833	G2832E	2832	Missense	proximal	-1	no	9.890	9.872	EPSD	ICGC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	P15924	DSP	P49841	GSK3B	S2833	G2840R	2840	Missense	distal	7	no	9.890	10.308	EPSD	ICGC	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	P15924	DSP	P49841	GSK3B	S2835	R2842C	2842	Missense	distal	7	no	8.493	8.447	EPSD	ICGC;COSMIC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	P15924	DSP	P49841	GSK3B	S2835	R2834H	2834	Missense	proximal	-1	no	8.493	8.578	EPSD	ICGC;COSMIC;GDSC;CCLE	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	P15924	DSP	P49841	GSK3B	S2835	G2828S	2828	Missense	distal	-7	no	8.493	8.495	EPSD	ICGC	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	P15924	DSP	P49841	GSK3B	S2835	S2829F	2829	Missense	distal	-6	no	8.493	8.439	EPSD	ICGC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	P15924	DSP	P49841	GSK3B	S2835	S2837Y	2837	Missense	proximal	2	no	8.493	8.260	EPSD	ICGC;COSMIC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	P15924	DSP	P49841	GSK3B	S2835	R2834L	2834	Missense	proximal	-1	no	8.493	8.555	EPSD	ICGC	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	P15924	DSP	P49841	GSK3B	S2835	G2832E	2832	Missense	distal	-3	no	8.493	8.510	EPSD	ICGC	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	P15924	DSP	P49841	GSK3B	S2835	G2840R	2840	Missense	distal	5	no	8.493	8.766	EPSD	ICGC	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	P15924	DSP	P49841	GSK3B	S2837	R2842C	2842	Missense	distal	5	no	9.051	7.494	EPSD	ICGC;COSMIC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	P15924	DSP	P49841	GSK3B	S2837	R2834H	2834	Missense	distal	-3	no	9.051	8.994	EPSD	ICGC;COSMIC;GDSC;CCLE	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	P15924	DSP	P49841	GSK3B	S2837	S2837Y	2837	Missense	central	0	yes	9.051	0.000	EPSD	ICGC;COSMIC	6.007	Loss
CMGC_GSK_GSK3B_ST	P15924	DSP	P49841	GSK3B	S2837	S2843N	2843	Missense	distal	6	no	9.051	9.044	EPSD	ICGC;COSMIC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	P15924	DSP	P49841	GSK3B	S2837	R2834L	2834	Missense	distal	-3	no	9.051	8.891	EPSD	ICGC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	P15924	DSP	P49841	GSK3B	S2837	G2832E	2832	Missense	distal	-5	no	9.051	9.016	EPSD	ICGC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	P15924	DSP	P49841	GSK3B	S2837	G2840R	2840	Missense	distal	3	no	9.051	8.636	EPSD	ICGC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	P15924	DSP	P49841	GSK3B	S2839	R2842C	2842	Missense	distal	3	no	7.703	7.858	EPSD	ICGC;COSMIC	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	P15924	DSP	P49841	GSK3B	S2839	R2834H	2834	Missense	distal	-5	no	7.703	7.172	EPSD	ICGC;COSMIC;GDSC;CCLE	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	P15924	DSP	P49841	GSK3B	S2839	S2837Y	2837	Missense	proximal	-2	no	7.703	7.384	EPSD	ICGC;COSMIC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	P15924	DSP	P49841	GSK3B	S2839	S2843N	2843	Missense	distal	4	no	7.703	4.093	EPSD	ICGC;COSMIC	6.007	Loss
CMGC_GSK_GSK3B_ST	P15924	DSP	P49841	GSK3B	S2839	R2834L	2834	Missense	distal	-5	no	7.703	7.114	EPSD	ICGC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	P15924	DSP	P49841	GSK3B	S2839	S2845P	2845	Missense	distal	6	no	7.703	7.705	EPSD	ICGC;COSMIC	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	P15924	DSP	P49841	GSK3B	S2839	G2832E	2832	Missense	distal	-7	no	7.703	7.737	EPSD	ICGC	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	P15924	DSP	P49841	GSK3B	S2839	G2840R	2840	Missense	proximal	1	no	7.703	8.577	EPSD	ICGC	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	P15924	DSP	P49841	GSK3B	S2841	R2842C	2842	Missense	proximal	1	no	9.923	7.920	EPSD	ICGC;COSMIC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	P15924	DSP	P49841	GSK3B	S2841	S2837Y	2837	Missense	distal	-4	no	9.923	9.122	EPSD	ICGC;COSMIC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	P15924	DSP	P49841	GSK3B	S2841	S2843N	2843	Missense	proximal	2	no	9.923	9.391	EPSD	ICGC;COSMIC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	P15924	DSP	P49841	GSK3B	S2841	R2834L	2834	Missense	distal	-7	no	9.923	9.905	EPSD	ICGC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	P15924	DSP	P49841	GSK3B	S2841	S2845P	2845	Missense	distal	4	no	9.923	6.952	EPSD	ICGC;COSMIC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	P15924	DSP	P49841	GSK3B	S2841	G2840R	2840	Missense	proximal	-1	no	9.923	9.779	EPSD	ICGC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	P15924	DSP	P49841	GSK3B	S2841	G2848E	2848	Missense	distal	7	no	9.923	9.942	EPSD	ICGC;COSMIC	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	P15924	DSP	P49841	GSK3B	S2845	R2842C	2842	Missense	distal	-3	no	9.477	9.411	PhosphoSitePlus;EPSD	ICGC;COSMIC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	P15924	DSP	P49841	GSK3B	S2845	S2843N	2843	Missense	proximal	-2	no	9.477	9.248	PhosphoSitePlus;EPSD	ICGC;COSMIC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	P15924	DSP	P49841	GSK3B	S2845	S2845P	2845	Missense	central	0	yes	9.477	0.000	PhosphoSitePlus;EPSD	ICGC;COSMIC	6.007	Loss
CMGC_GSK_GSK3B_ST	P15924	DSP	P49841	GSK3B	S2845	G2840R	2840	Missense	distal	-5	no	9.477	9.708	PhosphoSitePlus;EPSD	ICGC	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	P15924	DSP	P49841	GSK3B	S2845	G2848E	2848	Missense	distal	3	no	9.477	9.413	PhosphoSitePlus;EPSD	ICGC;COSMIC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	P15924	DSP	P49841	GSK3B	S2849	R2842C	2842	Missense	distal	-7	no	6.665	6.669	EPSD;PhosphoSitePlus	ICGC;COSMIC	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	P15924	DSP	P49841	GSK3B	S2849	S2856F	2856	Missense	distal	7	no	6.665	6.743	EPSD;PhosphoSitePlus	ICGC;COSMIC;GDSC;CCLE	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	P15924	DSP	P49841	GSK3B	S2849	S2843N	2843	Missense	distal	-6	no	6.665	6.663	EPSD;PhosphoSitePlus	ICGC;COSMIC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	P15924	DSP	P49841	GSK3B	S2849	S2845P	2845	Missense	distal	-4	no	6.665	6.102	EPSD;PhosphoSitePlus	ICGC;COSMIC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	P15924	DSP	P49841	GSK3B	S2849	G2848E	2848	Missense	proximal	-1	no	6.665	6.647	EPSD;PhosphoSitePlus	ICGC;COSMIC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	P15924	DSP	P49841	GSK3B	T2853	S2856F	2856	Missense	distal	3	no	6.657	6.446	EPSD	ICGC;COSMIC;GDSC;CCLE	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	P15924	DSP	P49841	GSK3B	T2853	G2848E	2848	Missense	distal	-5	no	6.657	6.622	EPSD	ICGC;COSMIC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	P15924	DSP	P49841	GSK3B	T2853	S2859F	2859	Missense	distal	6	no	6.657	6.645	EPSD	ICGC;GDSC;CCLE	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	P15924	DSP	P49841	GSK3B	S2857	S2856F	2856	Missense	proximal	-1	no	7.059	6.929	EPSD	ICGC;COSMIC;GDSC;CCLE	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	P15924	DSP	P49841	GSK3B	S2857	S2859F	2859	Missense	proximal	2	no	7.059	6.714	EPSD	ICGC;GDSC;CCLE	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	P15924	DSP	P49841	GSK3B	S2861	S2856F	2856	Missense	distal	-5	no	8.185	8.744	EPSD	ICGC;COSMIC;GDSC;CCLE	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	P15924	DSP	P49841	GSK3B	S2861	S2859F	2859	Missense	proximal	-2	no	8.185	7.854	EPSD	ICGC;GDSC;CCLE	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	P15924	DSP	P49841	GSK3B	S2863	S2856F	2856	Missense	distal	-7	no	7.467	7.478	EPSD	ICGC;COSMIC;GDSC;CCLE	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	P15924	DSP	P49841	GSK3B	S2863	S2859F	2859	Missense	distal	-4	no	7.467	6.313	EPSD	ICGC;GDSC;CCLE	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	P60484	PTEN	P49841	GSK3B	S362	S360R	360	Missense	proximal	-2	no	9.223	9.108	EPSD;PhosphoSitePlus	ICGC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	P60484	PTEN	P49841	GSK3B	T366	S360R	360	Missense	distal	-6	no	10.540	10.483	PhosphoSitePlus;EPSD	ICGC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	Q07812	BAX	P49841	GSK3B	S87	F93L	93	Missense	distal	6	no	7.032	7.040	EPSD	ICGC;COSMIC	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	Q07812	BAX	P49841	GSK3B	S87	S87F	87	Missense	central	0	yes	7.032	0.000	EPSD	ICGC;COSMIC	6.007	Loss
CMGC_GSK_GSK3B_ST	Q07812	BAX	P49841	GSK3B	S87	P88F	88	Missense	proximal	1	no	7.032	2.801	EPSD	ICGC	6.007	Loss
CMGC_GSK_GSK3B_ST	Q07812	BAX	P49841	GSK3B	S163	L162I	162	Missense	proximal	-1	no	9.392	9.317	PhosphoSitePlus	ICGC;COSMIC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	P33076	CIITA	P49841	GSK3B	T740	P741S	741	Missense	proximal	1	no	7.825	3.980	EPSD	ICGC;COSMIC	6.007	Loss
CMGC_GSK_GSK3B_ST	P33076	CIITA	P49841	GSK3B	T740	A738T	738	Missense	proximal	-2	no	7.825	8.187	EPSD	ICGC	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	P33076	CIITA	P49841	GSK3B	S834	R839H	839	Missense	distal	5	no	6.984	5.994	EPSD	ICGC;COSMIC	6.007	Loss
CMGC_GSK_GSK3B_ST	P33076	CIITA	P49841	GSK3B	S834	R839C	839	Missense	distal	5	no	6.984	5.427	EPSD	ICGC;COSMIC	6.007	Loss
CMGC_GSK_GSK3B_ST	P33076	CIITA	P49841	GSK3B	S834	G831V	831	Missense	distal	-3	no	6.984	7.155	EPSD	ICGC	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	Q14103	HNRNPD	P49841	GSK3B	S43	A41T	41	Missense	proximal	-2	no	5.737	6.099	EPSD	ICGC;COSMIC	6.007	Gain
CMGC_GSK_GSK3B_ST	Q14103	HNRNPD	P49841	GSK3B	S83	A90E	90	Missense	distal	7	no	11.052	10.744	PhosphoSitePlus	ICGC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	Q14103	HNRNPD	P49841	GSK3B	S83	P84T	84	Missense	proximal	1	no	11.052	7.861	PhosphoSitePlus	ICGC;COSMIC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	Q14103	HNRNPD	P49841	GSK3B	S87	A92T	92	Missense	distal	5	no	6.223	6.275	EPSD	ICGC;COSMIC	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	Q14103	HNRNPD	P49841	GSK3B	S87	A92E	92	Missense	distal	5	no	6.223	6.607	EPSD	ICGC;COSMIC	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	Q14103	HNRNPD	P49841	GSK3B	S87	Q93K	93	Missense	distal	6	no	6.223	6.221	EPSD	ICGC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	Q14103	HNRNPD	P49841	GSK3B	S87	A90E	90	Missense	distal	3	no	6.223	6.541	EPSD	ICGC	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	Q14103	HNRNPD	P49841	GSK3B	S87	P84T	84	Missense	distal	-3	no	6.223	6.365	EPSD	ICGC;COSMIC	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	Q14103	HNRNPD	P49841	GSK3B	T91	A92T	92	Missense	proximal	1	no	6.257	6.798	EPSD	ICGC;COSMIC	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	Q14103	HNRNPD	P49841	GSK3B	T91	A92E	92	Missense	proximal	1	no	6.257	6.156	EPSD	ICGC;COSMIC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	Q14103	HNRNPD	P49841	GSK3B	T91	Q93K	93	Missense	proximal	2	no	6.257	5.987	EPSD	ICGC	6.007	Loss
CMGC_GSK_GSK3B_ST	Q14103	HNRNPD	P49841	GSK3B	T91	A90E	90	Missense	proximal	-1	no	6.257	6.400	EPSD	ICGC	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	Q14103	HNRNPD	P49841	GSK3B	T91	P84T	84	Missense	distal	-7	no	6.257	6.286	EPSD	ICGC;COSMIC	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	P23246	SFPQ	P49841	GSK3B	S33	P34S	34	Missense	proximal	1	no	6.095	2.250	EPSD	ICGC;COSMIC	6.007	Loss
CMGC_GSK_GSK3B_ST	P23246	SFPQ	P49841	GSK3B	S33	M38I	38	Missense	distal	5	no	6.095	5.567	EPSD	ICGC;COSMIC	6.007	Loss
CMGC_GSK_GSK3B_ST	P23246	SFPQ	P49841	GSK3B	T355	G359V	359	Missense	distal	4	no	5.205	6.058	EPSD	ICGC	6.007	Gain
CMGC_GSK_GSK3B_ST	P23246	SFPQ	P49841	GSK3B	S379	N377S	377	Missense	proximal	-2	no	8.533	8.761	EPSD	ICGC;COSMIC	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	P23246	SFPQ	P49841	GSK3B	S379	N384T	384	Missense	distal	5	no	8.533	8.831	EPSD	ICGC;COSMIC	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	P23246	SFPQ	P49841	GSK3B	T476	H483N	483	Missense	distal	7	no	6.076	5.573	EPSD	ICGC	6.007	Loss
CMGC_GSK_GSK3B_ST	P23246	SFPQ	P49841	GSK3B	T476	P477T	477	Missense	proximal	1	no	6.076	2.885	EPSD	ICGC;COSMIC	6.007	Loss
CMGC_GSK_GSK3B_ST	P23246	SFPQ	P49841	GSK3B	T687	G692C	692	Missense	distal	5	no	7.106	5.824	PhosphoSitePlus	ICGC	6.007	Loss
CMGC_GSK_GSK3B_ST	Q96KS0	EGLN2	P49841	GSK3B	S70	R77L	77	Missense	distal	7	no	8.517	8.065	EPSD	ICGC;COSMIC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	Q96KS0	EGLN2	P49841	GSK3B	S74	R77L	77	Missense	distal	3	no	8.306	8.377	EPSD	ICGC;COSMIC	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	Q96KS0	EGLN2	P49841	GSK3B	S130	D127G	127	Missense	distal	-3	no	8.108	8.058	EPSD	ICGC;COSMIC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	Q96KS0	EGLN2	P49841	GSK3B	S130	P129S	129	Missense	proximal	-1	no	8.108	8.052	EPSD	ICGC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	Q9UKA4	AKAP11	P49841	GSK3B	S29	Q25R	25	Missense	distal	-4	no	7.135	6.777	EPSD	ICGC;COSMIC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	Q9UKA4	AKAP11	P49841	GSK3B	S130	P131S	131	Missense	proximal	1	no	7.951	4.106	EPSD	ICGC;COSMIC	6.007	Loss
CMGC_GSK_GSK3B_ST	Q9UKA4	AKAP11	P49841	GSK3B	S130	P134Q	134	Missense	distal	4	no	7.951	7.359	EPSD	ICGC;COSMIC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	Q9UKA4	AKAP11	P49841	GSK3B	S267	P262H	262	Missense	distal	-5	no	5.939	6.262	EPSD	ICGC;COSMIC	6.007	Gain
CMGC_GSK_GSK3B_ST	Q9UKA4	AKAP11	P49841	GSK3B	T269	P262H	262	Missense	distal	-7	no	7.843	7.863	EPSD	ICGC;COSMIC	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	Q9UKA4	AKAP11	P49841	GSK3B	S288	R283G	283	Missense	distal	-5	no	8.102	7.871	EPSD	ICGC;COSMIC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	Q9UKA4	AKAP11	P49841	GSK3B	S288	S292N	292	Missense	distal	4	no	8.102	4.492	EPSD	ICGC;COSMIC	6.007	Loss
CMGC_GSK_GSK3B_ST	Q9UKA4	AKAP11	P49841	GSK3B	S288	Q295R	295	Missense	distal	7	no	8.102	8.450	EPSD	ICGC;COSMIC	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	Q9UKA4	AKAP11	P49841	GSK3B	S433	D432Y	432	Missense	proximal	-1	no	7.168	7.088	EPSD	ICGC;COSMIC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	Q9UKA4	AKAP11	P49841	GSK3B	S433	R435H	435	Missense	proximal	2	no	7.168	6.825	EPSD	ICGC;COSMIC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	Q9UKA4	AKAP11	P49841	GSK3B	S440	R435H	435	Missense	distal	-5	no	6.845	6.314	EPSD	ICGC;COSMIC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	Q9UKA4	AKAP11	P49841	GSK3B	S444	S448I	448	Missense	distal	4	no	10.311	6.989	EPSD	ICGC;COSMIC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	Q9UKA4	AKAP11	P49841	GSK3B	S448	S448I	448	Missense	central	0	yes	11.396	0.000	EPSD	ICGC;COSMIC	6.007	Loss
CMGC_GSK_GSK3B_ST	Q9UKA4	AKAP11	P49841	GSK3B	S452	G459V	459	Missense	distal	7	no	7.451	7.856	EPSD	ICGC;COSMIC	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	Q9UKA4	AKAP11	P49841	GSK3B	S452	S456I	456	Missense	distal	4	no	7.451	4.129	EPSD	ICGC	6.007	Loss
CMGC_GSK_GSK3B_ST	Q9UKA4	AKAP11	P49841	GSK3B	S452	S448I	448	Missense	distal	-4	no	7.451	4.968	EPSD	ICGC;COSMIC	6.007	Loss
CMGC_GSK_GSK3B_ST	Q9UKA4	AKAP11	P49841	GSK3B	S456	G459V	459	Missense	distal	3	no	7.411	7.159	EPSD	ICGC;COSMIC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	Q9UKA4	AKAP11	P49841	GSK3B	S456	S456I	456	Missense	central	0	yes	7.411	0.000	EPSD	ICGC	6.007	Loss
CMGC_GSK_GSK3B_ST	Q9UKA4	AKAP11	P49841	GSK3B	S483	T487I	487	Missense	distal	4	no	6.479	4.026	EPSD	ICGC	6.007	Loss
CMGC_GSK_GSK3B_ST	Q9UKA4	AKAP11	P49841	GSK3B	S673	P668H	668	Missense	distal	-5	no	5.835	6.159	EPSD	ICGC;COSMIC	6.007	Gain
CMGC_GSK_GSK3B_ST	Q9UKA4	AKAP11	P49841	GSK3B	S970	E969V	969	Missense	proximal	-1	no	6.628	6.688	EPSD	ICGC	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	Q9UKA4	AKAP11	P49841	GSK3B	S970	E969K	969	Missense	proximal	-1	no	6.628	6.694	EPSD	ICGC	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	Q9UKA4	AKAP11	P49841	GSK3B	S974	E969V	969	Missense	distal	-5	no	7.986	8.135	EPSD	ICGC	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	Q9UKA4	AKAP11	P49841	GSK3B	S974	E969K	969	Missense	distal	-5	no	7.986	7.755	EPSD	ICGC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	Q9UKA4	AKAP11	P49841	GSK3B	S985	P989H	989	Missense	distal	4	no	8.661	7.876	EPSD	ICGC;COSMIC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	Q9UKA4	AKAP11	P49841	GSK3B	S1019	L1020V	1020	Missense	proximal	1	no	6.011	5.880	EPSD	ICGC	6.007	Loss
CMGC_GSK_GSK3B_ST	Q9UKA4	AKAP11	P49841	GSK3B	S1019	E1021D	1021	Missense	proximal	2	no	6.011	6.190	EPSD	ICGC	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	Q9UKA4	AKAP11	P49841	GSK3B	T1100	P1101S	1101	Missense	proximal	1	no	9.354	5.509	EPSD	ICGC	6.007	Loss
CMGC_GSK_GSK3B_ST	Q9UKA4	AKAP11	P49841	GSK3B	S1103	P1101S	1101	Missense	proximal	-2	no	6.647	6.391	EPSD	ICGC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	Q9UKA4	AKAP11	P49841	GSK3B	S1103	R1110Q	1110	Missense	distal	7	no	6.647	6.299	EPSD	ICGC;COSMIC;GDSC;CCLE	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	Q9UKA4	AKAP11	P49841	GSK3B	T1104	P1101S	1101	Missense	distal	-3	no	7.658	7.774	EPSD	ICGC	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	Q9UKA4	AKAP11	P49841	GSK3B	S1109	R1110Q	1110	Missense	proximal	1	no	7.499	6.551	EPSD	ICGC;COSMIC;GDSC;CCLE	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	Q9UKA4	AKAP11	P49841	GSK3B	T1140	S1144P	1144	Missense	distal	4	no	9.758	6.787	EPSD;PhosphoSitePlus	ICGC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	Q9UKA4	AKAP11	P49841	GSK3B	S1144	S1144P	1144	Missense	central	0	yes	6.613	0.000	EPSD	ICGC	6.007	Loss
CMGC_GSK_GSK3B_ST	Q9UKA4	AKAP11	P49841	GSK3B	S1240	N1234I	1234	Missense	distal	-6	no	6.265	6.205	EPSD	ICGC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	Q9UKA4	AKAP11	P49841	GSK3B	S1240	R1239K	1239	Missense	proximal	-1	no	6.265	6.458	EPSD	ICGC;COSMIC	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	Q9UKA4	AKAP11	P49841	GSK3B	S1242	R1239K	1239	Missense	distal	-3	no	6.052	5.907	EPSD	ICGC;COSMIC	6.007	Loss
CMGC_GSK_GSK3B_ST	Q9UKA4	AKAP11	P49841	GSK3B	S1460	S1464I	1464	Missense	distal	4	no	7.045	3.723	EPSD	ICGC	6.007	Loss
CMGC_GSK_GSK3B_ST	Q9UKA4	AKAP11	P49841	GSK3B	S1483	L1489F	1489	Missense	distal	6	no	6.866	6.859	EPSD	ICGC;COSMIC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	Q9UKA4	AKAP11	P49841	GSK3B	S1483	V1478F	1478	Missense	distal	-5	no	6.866	6.847	EPSD	ICGC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	Q9UKA4	AKAP11	P49841	GSK3B	S1611	K1616M	1616	Missense	distal	5	no	7.659	8.079	EPSD	ICGC;COSMIC	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	Q9UKA4	AKAP11	P49841	GSK3B	S1611	A1613S	1613	Missense	proximal	2	no	7.659	7.652	EPSD	ICGC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	Q9UKA4	AKAP11	P49841	GSK3B	S1611	Q1604H	1604	Missense	distal	-7	no	7.659	7.662	EPSD	ICGC	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	Q9UKA4	AKAP11	P49841	GSK3B	S1611	G1610C	1610	Missense	proximal	-1	no	7.659	7.617	EPSD	ICGC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	Q9UKA4	AKAP11	P49841	GSK3B	S1615	K1616M	1616	Missense	proximal	1	no	7.370	7.329	EPSD	ICGC;COSMIC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	Q9UKA4	AKAP11	P49841	GSK3B	S1615	A1613S	1613	Missense	proximal	-2	no	7.370	7.704	EPSD	ICGC	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	Q9UKA4	AKAP11	P49841	GSK3B	S1615	G1610C	1610	Missense	distal	-5	no	7.370	7.423	EPSD	ICGC	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	Q9UKA4	AKAP11	P49841	GSK3B	S1683	G1676W	1676	Missense	distal	-7	no	6.249	6.279	EPSD	ICGC;COSMIC	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	Q9NW38	FANCL	P49841	GSK3B	S77	Q71H	71	Missense	distal	-6	no	8.094	8.064	EPSD	ICGC;COSMIC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	Q9NW38	FANCL	P49841	GSK3B	T178	I184T	184	Missense	distal	6	no	8.636	8.639	PhosphoSitePlus	ICGC;COSMIC	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	P56524	HDAC4	P49841	GSK3B	S210	P217L	217	Missense	distal	7	no	9.356	9.405	EPSD	ICGC	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	P56524	HDAC4	P49841	GSK3B	S215	P217L	217	Missense	proximal	2	no	10.763	10.379	EPSD	ICGC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	P56524	HDAC4	P49841	GSK3B	S628	G623W	623	Missense	distal	-5	no	8.322	8.297	EPSD	ICGC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	Q92993	KAT5	P49841	GSK3B	S86	R87H	87	Missense	proximal	1	no	8.784	7.403	PhosphoSitePlus;EPSD	ICGC;COSMIC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	Q92993	KAT5	P49841	GSK3B	S86	G89D	89	Missense	distal	3	no	8.784	8.835	PhosphoSitePlus;EPSD	ICGC	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	Q92993	KAT5	P49841	GSK3B	S86	G82R	82	Missense	distal	-4	no	8.784	8.025	PhosphoSitePlus;EPSD	ICGC;COSMIC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	Q92993	KAT5	P49841	GSK3B	S90	R87H	87	Missense	distal	-3	no	9.797	9.740	EPSD;PhosphoSitePlus	ICGC;COSMIC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	Q92993	KAT5	P49841	GSK3B	S90	G89D	89	Missense	proximal	-1	no	9.797	9.730	EPSD;PhosphoSitePlus	ICGC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	O95997	PTTG1	P49841	GSK3B	S103	A110G	110	Missense	distal	7	no	7.048	6.720	EPSD	ICGC;COSMIC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	O95997	PTTG1	P49841	GSK3B	S165	S171C	171	Missense	distal	6	no	7.639	7.626	EPSD	ICGC;COSMIC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	O95997	PTTG1	P49841	GSK3B	S171	S171C	171	Missense	central	0	yes	7.768	0.000	EPSD	ICGC;COSMIC	6.007	Loss
CMGC_GSK_GSK3B_ST	O95997	PTTG1	P49841	GSK3B	S171	W174L	174	Missense	distal	3	no	7.768	7.580	EPSD	ICGC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	O95997	PTTG1	P49841	GSK3B	S184	S184N	184	Missense	central	0	yes	6.074	0.000	PhosphoSitePlus;EPSD	ICGC;COSMIC	6.007	Loss
CMGC_GSK_GSK3B_ST	P14618	PKM	P49841	GSK3B	S6	P4T	4	Missense	proximal	-2	no	6.814	6.585	EPSD	ICGC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	P14618	PKM	P49841	GSK3B	S37	D34E	34	Missense	distal	-3	no	9.277	9.244	EPSD	ICGC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	P14618	PKM	P49841	GSK3B	S37	P38T	38	Missense	proximal	1	no	9.277	6.086	EPSD	ICGC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	P14618	PKM	P49841	GSK3B	S406	E410K	410	Missense	distal	4	no	6.023	4.841	EPSD	ICGC;COSMIC	6.007	Loss
CMGC_GSK_GSK3B_ST	P49841	GSK3B	P49841	GSK3B	T7	A11S	11	Missense	distal	4	no	4.452	6.864	EPSD	ICGC;COSMIC	6.007	Gain
CMGC_GSK_GSK3B_ST	P49841	GSK3B	P49841	GSK3B	S9	A11S	11	Missense	proximal	2	no	6.632	6.624	EPSD	ICGC;COSMIC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	P49841	GSK3B	P49841	GSK3B	T43	D49E	49	Missense	distal	6	no	7.636	7.638	EPSD;PhosphoSitePlus	ICGC	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	P49841	GSK3B	P49841	GSK3B	S55	D49E	49	Missense	distal	-6	no	7.192	7.155	EPSD	ICGC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	P49841	GSK3B	P49841	GSK3B	S55	Q52K	52	Missense	distal	-3	no	7.192	7.186	EPSD	ICGC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	P49841	GSK3B	P49841	GSK3B	S55	E53K	53	Missense	proximal	-2	no	7.192	7.161	EPSD	ICGC;COSMIC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	P49841	GSK3B	P49841	GSK3B	S215	S219Y	219	Missense	distal	4	no	7.507	3.994	EPSD	ICGC;COSMIC	6.007	Loss
CMGC_GSK_GSK3B_ST	P49841	GSK3B	P49841	GSK3B	S215	P212T	212	Missense	distal	-3	no	7.507	7.648	EPSD	ICGC	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	P49841	GSK3B	P49841	GSK3B	S219	S219Y	219	Missense	central	0	yes	6.818	0.000	EPSD	ICGC;COSMIC	6.007	Loss
CMGC_GSK_GSK3B_ST	P49841	GSK3B	P49841	GSK3B	S219	P212T	212	Missense	distal	-7	no	6.818	6.847	EPSD	ICGC	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	P49841	GSK3B	P49841	GSK3B	T275	I270V	270	Missense	distal	-5	no	7.582	7.689	EPSD	ICGC;COSMIC	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	P49841	GSK3B	P49841	GSK3B	T275	R278K	278	Missense	distal	3	no	7.582	7.826	EPSD	ICGC	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	P49841	GSK3B	P49841	GSK3B	T275	L273R	273	Missense	proximal	-2	no	7.582	7.541	EPSD	ICGC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	P49841	GSK3B	P49841	GSK3B	T275	L273M	273	Missense	proximal	-2	no	7.582	7.325	EPSD	ICGC;COSMIC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	P49841	GSK3B	P49841	GSK3B	T390	S389P	389	Missense	proximal	-1	no	5.963	6.019	PhosphoSitePlus;EPSD	ICGC;COSMIC	6.007	Gain
CMGC_GSK_GSK3B_ST	Q96R06	SPAG5	P49841	GSK3B	S8	L9F	9	Missense	proximal	1	no	6.916	5.545	EPSD	ICGC;COSMIC	6.007	Loss
CMGC_GSK_GSK3B_ST	Q96R06	SPAG5	P49841	GSK3B	S8	W2L	2	Missense	distal	-6	no	6.916	6.944	EPSD	ICGC;COSMIC	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	Q96R06	SPAG5	P49841	GSK3B	S10	L9F	9	Missense	proximal	-1	no	7.167	7.112	EPSD	ICGC;COSMIC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	Q96R06	SPAG5	P49841	GSK3B	S12	L9F	9	Missense	distal	-3	no	6.787	6.845	EPSD	ICGC;COSMIC	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	Q96R06	SPAG5	P49841	GSK3B	S14	L9F	9	Missense	distal	-5	no	6.677	7.128	EPSD	ICGC;COSMIC	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	Q96R06	SPAG5	P49841	GSK3B	T24	M22T	22	Missense	proximal	-2	no	5.855	6.214	EPSD	ICGC;COSMIC	6.007	Gain
CMGC_GSK_GSK3B_ST	Q96R06	SPAG5	P49841	GSK3B	S48	L53M	53	Missense	distal	5	no	7.090	7.278	EPSD	ICGC	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	Q96R06	SPAG5	P49841	GSK3B	S48	L53P	53	Missense	distal	5	no	7.090	8.371	EPSD	ICGC;COSMIC	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	Q96R06	SPAG5	P49841	GSK3B	S52	L53P	53	Missense	proximal	1	no	4.847	7.708	EPSD	ICGC;COSMIC	6.007	Gain
CMGC_GSK_GSK3B_ST	Q96R06	SPAG5	P49841	GSK3B	S110	I105V	105	Missense	distal	-5	no	6.052	6.159	EPSD	ICGC;COSMIC	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	Q96R06	SPAG5	P49841	GSK3B	S110	P104T	104	Missense	distal	-6	no	6.052	5.973	EPSD	ICGC	6.007	Loss
CMGC_GSK_GSK3B_ST	Q96R06	SPAG5	P49841	GSK3B	T111	I105V	105	Missense	distal	-6	no	10.369	10.364	EPSD;PhosphoSitePlus	ICGC;COSMIC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	Q96R06	SPAG5	P49841	GSK3B	T111	P104T	104	Missense	distal	-7	no	10.369	10.397	EPSD;PhosphoSitePlus	ICGC	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	Q96R06	SPAG5	P49841	GSK3B	S135	D142Y	142	Missense	distal	7	no	5.993	6.381	EPSD	ICGC	6.007	Gain
CMGC_GSK_GSK3B_ST	Q96R06	SPAG5	P49841	GSK3B	S205	E212D	212	Missense	distal	7	no	6.983	6.998	EPSD	ICGC;COSMIC	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	Q96R06	SPAG5	P49841	GSK3B	S205	P198L	198	Missense	distal	-7	no	6.983	6.984	EPSD	ICGC;COSMIC	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	Q96R06	SPAG5	P49841	GSK3B	S205	P209S	209	Missense	distal	4	no	6.983	9.954	EPSD	ICGC;COSMIC	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	Q96R06	SPAG5	P49841	GSK3B	S205	N208K	208	Missense	distal	3	no	6.983	6.808	EPSD	ICGC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	Q96R06	SPAG5	P49841	GSK3B	T377	R370Q	370	Missense	distal	-7	no	6.240	6.237	EPSD	ICGC;COSMIC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	Q96R06	SPAG5	P49841	GSK3B	T377	D371E	371	Missense	distal	-6	no	6.240	6.204	EPSD	ICGC;COSMIC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	Q96R06	SPAG5	P49841	GSK3B	T377	D371N	371	Missense	distal	-6	no	6.240	6.263	EPSD	ICGC	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	Q96R06	SPAG5	P49841	GSK3B	T377	T376N	376	Missense	proximal	-1	no	6.240	6.377	EPSD	ICGC	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	Q96R06	SPAG5	P49841	GSK3B	T377	A372D	372	Missense	distal	-5	no	6.240	6.235	EPSD	ICGC;COSMIC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	Q96R06	SPAG5	P49841	GSK3B	T389	P393Q	393	Missense	distal	4	no	7.234	6.641	EPSD	ICGC;COSMIC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	Q96R06	SPAG5	P49841	GSK3B	S397	S401C	401	Missense	distal	4	no	6.387	0.254	EPSD	ICGC	6.007	Loss
CMGC_GSK_GSK3B_ST	Q96R06	SPAG5	P49841	GSK3B	S397	T398K	398	Missense	proximal	1	no	6.387	6.032	EPSD	ICGC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	Q96R06	SPAG5	P49841	GSK3B	S397	P393Q	393	Missense	distal	-4	no	6.387	6.121	EPSD	ICGC;COSMIC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	Q96R06	SPAG5	P49841	GSK3B	S397	S401F	401	Missense	distal	4	no	6.387	2.773	EPSD	ICGC	6.007	Loss
CMGC_GSK_GSK3B_ST	Q96R06	SPAG5	P49841	GSK3B	S411	E414D	414	Missense	distal	3	no	6.282	6.396	EPSD	ICGC;COSMIC	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	Q96R06	SPAG5	P49841	GSK3B	T466	T473N	473	Missense	distal	7	no	6.440	6.621	EPSD	ICGC	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	Q96R06	SPAG5	P49841	GSK3B	S559	R554K	554	Missense	distal	-5	no	6.077	5.580	EPSD	ICGC;COSMIC	6.007	Loss
CMGC_GSK_GSK3B_ST	Q96R06	SPAG5	P49841	GSK3B	S559	L560I	560	Missense	proximal	1	no	6.077	5.057	EPSD	ICGC	6.007	Loss
CMGC_GSK_GSK3B_ST	Q96R06	SPAG5	P49841	GSK3B	T656	S662Y	662	Missense	distal	6	no	6.589	6.583	EPSD	ICGC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	Q96R06	SPAG5	P49841	GSK3B	T937	S936L	936	Missense	proximal	-1	no	6.516	6.441	EPSD;PhosphoSitePlus	ICGC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	Q96R06	SPAG5	P49841	GSK3B	T937	T937A	937	Missense	central	0	yes	6.516	0.000	EPSD;PhosphoSitePlus	ICGC	6.007	Loss
CMGC_GSK_GSK3B_ST	Q96R06	SPAG5	P49841	GSK3B	T963	P964S	964	Missense	proximal	1	no	6.325	2.480	EPSD	ICGC;COSMIC	6.007	Loss
CMGC_GSK_GSK3B_ST	Q96R06	SPAG5	P49841	GSK3B	T963	E962D	962	Missense	proximal	-1	no	6.325	6.276	EPSD	ICGC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	O60341	KDM1A	P49841	GSK3B	S69	G72V	72	Missense	distal	3	no	6.965	6.713	EPSD	ICGC;COSMIC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	O60341	KDM1A	P49841	GSK3B	T95	P91S	91	Missense	distal	-4	no	8.646	9.209	EPSD	ICGC;COSMIC	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	O60341	KDM1A	P49841	GSK3B	S683	S687I	687	Missense	distal	4	no	8.685	5.363	PhosphoSitePlus	ICGC	6.007	Loss
CMGC_GSK_GSK3B_ST	O60341	KDM1A	P49841	GSK3B	S683	G679R	679	Missense	distal	-4	no	8.685	7.926	PhosphoSitePlus	ICGC;COSMIC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	O60341	KDM1A	P49841	GSK3B	T841	P842Q	842	Missense	proximal	1	no	7.729	4.460	EPSD	ICGC;COSMIC	6.007	Loss
CMGC_GSK_GSK3B_ST	O60341	KDM1A	P49841	GSK3B	T841	V844F	844	Missense	distal	3	no	7.729	7.726	EPSD	ICGC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	O60341	KDM1A	P49841	GSK3B	T841	R838C	838	Missense	distal	-3	no	7.729	7.663	EPSD	ICGC;COSMIC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	Q9Y2X9	ZNF281	P49841	GSK3B	S160	A154D	154	Missense	distal	-6	no	7.051	7.015	EPSD	ICGC;COSMIC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	Q9Y2X9	ZNF281	P49841	GSK3B	S255	D248V	248	Missense	distal	-7	no	8.769	8.788	EPSD	ICGC;COSMIC	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	Q9Y2X9	ZNF281	P49841	GSK3B	S255	L254F	254	Missense	proximal	-1	no	8.769	8.714	EPSD	ICGC;COSMIC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	Q9Y2X9	ZNF281	P49841	GSK3B	S255	G249R	249	Missense	distal	-6	no	8.769	8.696	EPSD	ICGC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	Q9Y2X9	ZNF281	P49841	GSK3B	S255	A252T	252	Missense	distal	-3	no	8.769	8.774	EPSD	ICGC;COSMIC;GDSC	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	Q9Y2X9	ZNF281	P49841	GSK3B	S484	G491R	491	Missense	distal	7	no	6.141	6.559	EPSD	ICGC;COSMIC	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	Q9Y2X9	ZNF281	P49841	GSK3B	S638	V633A	633	Missense	distal	-5	no	7.944	7.642	PhosphoSitePlus	ICGC;COSMIC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	Q9Y2X9	ZNF281	P49841	GSK3B	S837	K840N	840	Missense	distal	3	no	6.375	6.550	EPSD	ICGC;COSMIC	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	Q9Y2X9	ZNF281	P49841	GSK3B	S876	T872K	872	Missense	distal	-4	no	6.694	6.165	EPSD	ICGC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	Q9Y2X9	ZNF281	P49841	GSK3B	S879	T872K	872	Missense	distal	-7	no	7.940	7.935	EPSD	ICGC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	P38936	CDKN1A	P49841	GSK3B	S27	S31R	31	Missense	distal	4	no	8.454	5.417	EPSD	ICGC;COSMIC	6.007	Loss
CMGC_GSK_GSK3B_ST	P38936	CDKN1A	P49841	GSK3B	S27	R32L	32	Missense	distal	5	no	8.454	7.811	EPSD	ICGC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	P38936	CDKN1A	P49841	GSK3B	S27	G23C	23	Missense	distal	-4	no	8.454	6.768	EPSD	ICGC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	P38936	CDKN1A	P49841	GSK3B	S27	E28K	28	Missense	proximal	1	no	8.454	8.742	EPSD	ICGC;COSMIC	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	P38936	CDKN1A	P49841	GSK3B	S130	P131T	131	Missense	proximal	1	no	7.588	4.397	EPSD	ICGC;COSMIC	6.007	Loss
CMGC_GSK_GSK3B_ST	P38936	CDKN1A	P49841	GSK3B	S130	P131Q	131	Missense	proximal	1	no	7.588	4.320	EPSD	ICGC;COSMIC	6.007	Loss
CMGC_GSK_GSK3B_ST	P38936	CDKN1A	P49841	GSK3B	S130	G129W	129	Missense	proximal	-1	no	7.588	7.556	EPSD	ICGC;COSMIC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	Q9BZS1	FOXP3	P49841	GSK3B	S19	S25R	25	Missense	distal	6	no	9.591	9.587	EPSD	ICGC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	Q9BZS1	FOXP3	P49841	GSK3B	S19	P24S	24	Missense	distal	5	no	9.591	8.637	EPSD	ICGC;COSMIC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	Q9BZS1	FOXP3	P49841	GSK3B	S23	S25R	25	Missense	proximal	2	no	6.432	6.451	EPSD	ICGC	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	Q9BZS1	FOXP3	P49841	GSK3B	S23	P24S	24	Missense	proximal	1	no	6.432	2.588	EPSD	ICGC;COSMIC	6.007	Loss
CMGC_GSK_GSK3B_ST	Q9BZS1	FOXP3	P49841	GSK3B	S25	S25R	25	Missense	central	0	yes	6.658	0.000	EPSD	ICGC	6.007	Loss
CMGC_GSK_GSK3B_ST	Q9BZS1	FOXP3	P49841	GSK3B	S25	P24S	24	Missense	proximal	-1	no	6.658	6.602	EPSD	ICGC;COSMIC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	O43602	DCX	P49841	GSK3B	S321	Q314K	314	Missense	distal	-7	no	6.656	6.662	EPSD	ICGC;COSMIC	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	O43602	DCX	P49841	GSK3B	S321	Q314R	314	Missense	distal	-7	no	6.656	6.659	EPSD	ICGC	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	P22670	RFX1	P49841	GSK3B	S60	Q53E	53	Missense	distal	-7	no	6.271	6.288	EPSD	ICGC;COSMIC	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	P22670	RFX1	P49841	GSK3B	S120	A119D	119	Missense	proximal	-1	no	10.017	10.111	EPSD;PhosphoSitePlus	ICGC;COSMIC	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	P22670	RFX1	P49841	GSK3B	S120	S117L	117	Missense	distal	-3	no	10.017	10.026	EPSD;PhosphoSitePlus	ICGC;COSMIC;CCLE	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	P22670	RFX1	P49841	GSK3B	S120	S123C	123	Missense	distal	3	no	10.017	9.801	EPSD;PhosphoSitePlus	ICGC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	P22670	RFX1	P49841	GSK3B	T124	A119D	119	Missense	distal	-5	no	6.700	6.695	PhosphoSitePlus;EPSD	ICGC;COSMIC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	P22670	RFX1	P49841	GSK3B	T124	S123C	123	Missense	proximal	-1	no	6.700	6.664	PhosphoSitePlus;EPSD	ICGC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	P22670	RFX1	P49841	GSK3B	T124	G129D	129	Missense	distal	5	no	6.700	6.764	PhosphoSitePlus;EPSD	ICGC;COSMIC	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	P22670	RFX1	P49841	GSK3B	T128	S123C	123	Missense	distal	-5	no	5.993	6.513	EPSD	ICGC	6.007	Gain
CMGC_GSK_GSK3B_ST	P22670	RFX1	P49841	GSK3B	T128	G129D	129	Missense	proximal	1	no	5.993	6.084	EPSD	ICGC;COSMIC	6.007	Gain
CMGC_GSK_GSK3B_ST	P22670	RFX1	P49841	GSK3B	S159	N165K	165	Missense	distal	6	no	7.671	7.672	EPSD	ICGC	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	P22670	RFX1	P49841	GSK3B	S159	H157N	157	Missense	proximal	-2	no	7.671	7.548	EPSD	ICGC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	P22670	RFX1	P49841	GSK3B	S204	Q208K	208	Missense	distal	4	no	5.883	6.243	EPSD	ICGC;COSMIC	6.007	Gain
CMGC_GSK_GSK3B_ST	P22670	RFX1	P49841	GSK3B	S209	H203L	203	Missense	distal	-6	no	6.371	6.403	EPSD	ICGC;COSMIC	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	P22670	RFX1	P49841	GSK3B	S209	A213D	213	Missense	distal	4	no	6.371	6.359	EPSD	ICGC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	P22670	RFX1	P49841	GSK3B	S209	Q208K	208	Missense	proximal	-1	no	6.371	6.533	EPSD	ICGC;COSMIC	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	P22670	RFX1	P49841	GSK3B	T253	P257R	257	Missense	distal	4	no	6.227	6.160	EPSD	ICGC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	P22670	RFX1	P49841	GSK3B	S453	T448K	448	Missense	distal	-5	no	7.332	7.243	EPSD	ICGC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	P22670	RFX1	P49841	GSK3B	S453	E447K	447	Missense	distal	-6	no	7.332	7.331	EPSD	ICGC;COSMIC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	P22670	RFX1	P49841	GSK3B	S949	A945V	945	Missense	distal	-4	no	6.024	5.950	EPSD	ICGC;COSMIC	6.007	Loss
CMGC_GSK_GSK3B_ST	P22670	RFX1	P49841	GSK3B	S949	P954Q	954	Missense	distal	5	no	6.024	5.047	EPSD	ICGC;COSMIC	6.007	Loss
CMGC_GSK_GSK3B_ST	P08238	HSP90AB1	P49841	GSK3B	S470	R475C	475	Missense	distal	5	no	7.219	5.662	EPSD	ICGC;COSMIC	6.007	Loss
CMGC_GSK_GSK3B_ST	P08238	HSP90AB1	P49841	GSK3B	S470	R475H	475	Missense	distal	5	no	7.219	6.229	EPSD	ICGC;COSMIC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	P08238	HSP90AB1	P49841	GSK3B	S470	M466I	466	Missense	distal	-4	no	7.219	5.796	EPSD	ICGC;COSMIC	6.007	Loss
CMGC_GSK_GSK3B_ST	P08238	HSP90AB1	P49841	GSK3B	S669	S666F	666	Missense	distal	-3	no	6.872	6.939	EPSD	ICGC;COSMIC	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	Q15797	SMAD1	P49841	GSK3B	S11	S8F	8	Missense	distal	-3	no	6.040	6.106	EPSD	ICGC	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	Q15797	SMAD1	P49841	GSK3B	S11	S5R	5	Missense	distal	-6	no	6.040	5.982	EPSD	ICGC	6.007	Loss
CMGC_GSK_GSK3B_ST	Q15797	SMAD1	P49841	GSK3B	S11	L18I	18	Missense	distal	7	no	6.040	6.389	EPSD	ICGC;COSMIC	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	Q15797	SMAD1	P49841	GSK3B	S187	N180H	180	Missense	distal	-7	no	9.456	9.468	EPSD	ICGC;COSMIC	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	Q15797	SMAD1	P49841	GSK3B	S187	P188T	188	Missense	proximal	1	no	9.456	6.265	EPSD	ICGC;COSMIC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	Q15797	SMAD1	P49841	GSK3B	S187	P183S	183	Missense	distal	-4	no	9.456	10.020	EPSD	ICGC	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	Q15797	SMAD1	P49841	GSK3B	S195	T202A	202	Missense	distal	7	no	11.405	11.811	EPSD	ICGC;COSMIC	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	Q15797	SMAD1	P49841	GSK3B	S195	G197W	197	Missense	proximal	2	no	11.405	11.251	EPSD	ICGC;COSMIC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	Q15797	SMAD1	P49841	GSK3B	S195	P188T	188	Missense	distal	-7	no	11.405	11.433	EPSD	ICGC;COSMIC	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	Q15797	SMAD1	P49841	GSK3B	T202	T202A	202	Missense	central	0	yes	9.463	0.000	PhosphoSitePlus	ICGC;COSMIC	6.007	Loss
CMGC_GSK_GSK3B_ST	Q15797	SMAD1	P49841	GSK3B	T202	G197W	197	Missense	distal	-5	no	9.463	9.438	PhosphoSitePlus	ICGC;COSMIC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	Q15797	SMAD1	P49841	GSK3B	S206	T202A	202	Missense	distal	-4	no	10.197	9.372	EPSD	ICGC;COSMIC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	Q15797	SMAD1	P49841	GSK3B	T452	W446L	446	Missense	distal	-6	no	6.307	6.335	EPSD	ICGC;COSMIC	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	Q15797	SMAD1	P49841	GSK3B	T452	W446C	446	Missense	distal	-6	no	6.307	6.325	EPSD	ICGC	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	Q15797	SMAD1	P49841	GSK3B	T452	P457L	457	Missense	distal	5	no	6.307	5.026	EPSD	ICGC;COSMIC	6.007	Loss
CMGC_GSK_GSK3B_ST	Q15797	SMAD1	P49841	GSK3B	S456	P457L	457	Missense	proximal	1	no	7.866	5.006	EPSD	ICGC;COSMIC	6.007	Loss
CMGC_GSK_GSK3B_ST	Q15853	USF2	P49841	GSK3B	S151	G153S	153	Missense	proximal	2	no	6.172	6.431	EPSD	ICGC	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	Q15853	USF2	P49841	GSK3B	S155	G153S	153	Missense	proximal	-2	no	9.261	9.379	EPSD;PhosphoSitePlus	ICGC	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	Q07820	MCL1	P49841	GSK3B	S121	I119V	119	Missense	proximal	-2	no	7.881	7.859	EPSD;PhosphoSitePlus	ICGC;COSMIC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	Q07820	MCL1	P49841	GSK3B	S121	E125D	125	Missense	distal	4	no	7.881	7.478	EPSD;PhosphoSitePlus	ICGC;COSMIC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	Q07820	MCL1	P49841	GSK3B	S150	S155R	155	Missense	distal	5	no	6.613	6.929	EPSD	ICGC;COSMIC	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	Q07820	MCL1	P49841	GSK3B	S150	T156A	156	Missense	distal	6	no	6.613	6.609	EPSD	ICGC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	Q07820	MCL1	P49841	GSK3B	S150	L143V	143	Missense	distal	-7	no	6.613	6.634	EPSD	ICGC	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	Q07820	MCL1	P49841	GSK3B	S155	S155R	155	Missense	central	0	yes	6.717	0.000	EPSD	ICGC;COSMIC	6.007	Loss
CMGC_GSK_GSK3B_ST	Q07820	MCL1	P49841	GSK3B	S155	T156A	156	Missense	proximal	1	no	6.717	6.176	EPSD	ICGC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	Q07820	MCL1	P49841	GSK3B	S155	P161S	161	Missense	distal	6	no	6.717	6.715	EPSD	ICGC;COSMIC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	Q07820	MCL1	P49841	GSK3B	S159	S155R	155	Missense	distal	-4	no	9.113	7.926	PhosphoSitePlus;EPSD	ICGC;COSMIC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	Q07820	MCL1	P49841	GSK3B	S159	T156A	156	Missense	distal	-3	no	9.113	9.109	PhosphoSitePlus;EPSD	ICGC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	Q07820	MCL1	P49841	GSK3B	S159	P161S	161	Missense	proximal	2	no	9.113	8.669	PhosphoSitePlus;EPSD	ICGC;COSMIC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	Q07820	MCL1	P49841	GSK3B	S159	P166Q	166	Missense	distal	7	no	9.113	9.266	PhosphoSitePlus;EPSD	ICGC;COSMIC	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	Q07820	MCL1	P49841	GSK3B	T163	T156A	156	Missense	distal	-7	no	9.133	9.129	EPSD;PhosphoSitePlus	ICGC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	Q07820	MCL1	P49841	GSK3B	T163	P161S	161	Missense	proximal	-2	no	9.133	8.877	EPSD;PhosphoSitePlus	ICGC;COSMIC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	Q07820	MCL1	P49841	GSK3B	T163	P166Q	166	Missense	distal	3	no	9.133	9.078	EPSD;PhosphoSitePlus	ICGC;COSMIC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	Q07820	MCL1	P49841	GSK3B	S202	D195Y	195	Missense	distal	-7	no	8.126	8.151	EPSD	ICGC;COSMIC	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	Q07820	MCL1	P49841	GSK3B	S202	P198A	198	Missense	distal	-4	no	8.126	7.529	EPSD	ICGC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	Q07820	MCL1	P49841	GSK3B	S202	M199K	199	Missense	distal	-3	no	8.126	8.178	EPSD	ICGC	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	Q07820	MCL1	P49841	GSK3B	S202	S206R	206	Missense	distal	4	no	8.126	5.088	EPSD	ICGC	6.007	Loss
CMGC_GSK_GSK3B_ST	Q07820	MCL1	P49841	GSK3B	S202	K197E	197	Missense	distal	-5	no	8.126	8.356	EPSD	ICGC	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	Q07820	MCL1	P49841	GSK3B	S206	M199K	199	Missense	distal	-7	no	7.022	7.023	EPSD	ICGC	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	Q07820	MCL1	P49841	GSK3B	S206	S206R	206	Missense	central	0	yes	7.022	0.000	EPSD	ICGC	6.007	Loss
CMGC_GSK_GSK3B_ST	P24864	CCNE1	P49841	GSK3B	S103	P106H	106	Missense	distal	3	no	7.875	7.829	EPSD	ICGC;COSMIC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	P24864	CCNE1	P49841	GSK3B	S103	V107A	107	Missense	distal	4	no	7.875	7.854	EPSD	ICGC;COSMIC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	P24864	CCNE1	P49841	GSK3B	S387	L394I	394	Missense	distal	7	no	10.298	10.648	EPSD	ICGC	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	P24864	CCNE1	P49841	GSK3B	S391	L394I	394	Missense	distal	3	no	6.714	6.594	EPSD	ICGC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	P24864	CCNE1	P49841	GSK3B	T395	S399I	399	Missense	distal	4	no	9.736	6.414	EPSD;PhosphoSitePlus	ICGC;COSMIC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	P24864	CCNE1	P49841	GSK3B	T395	S399R	399	Missense	distal	4	no	9.736	6.698	EPSD;PhosphoSitePlus	ICGC;COSMIC;GDSC;CCLE	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	P24864	CCNE1	P49841	GSK3B	T395	G400D	400	Missense	distal	5	no	9.736	9.800	EPSD;PhosphoSitePlus	ICGC;COSMIC	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	P24864	CCNE1	P49841	GSK3B	T395	L394I	394	Missense	proximal	-1	no	9.736	9.662	EPSD;PhosphoSitePlus	ICGC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	Q9Y6K9	IKBKG	P49841	GSK3B	S31	D25Y	25	Missense	distal	-6	no	9.414	9.353	PhosphoSitePlus;EPSD	ICGC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	Q9Y6K9	IKBKG	P49841	GSK3B	S31	S31F	31	Missense	central	0	yes	9.414	0.000	PhosphoSitePlus;EPSD	ICGC	6.007	Loss
CMGC_GSK_GSK3B_ST	Q9Y6K9	IKBKG	P49841	GSK3B	S31	G28C	28	Missense	distal	-3	no	9.414	9.522	PhosphoSitePlus;EPSD	ICGC;COSMIC	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	Q9Y6K9	IKBKG	P49841	GSK3B	S31	E29A	29	Missense	proximal	-2	no	9.414	9.182	PhosphoSitePlus;EPSD	ICGC;COSMIC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	Q9BPU6	DPYSL5	P49841	GSK3B	T490	R489L	489	Missense	proximal	-1	no	6.275	6.337	EPSD	ICGC	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	Q9BPU6	DPYSL5	P49841	GSK3B	T490	K483N	483	Missense	distal	-7	no	6.275	6.259	EPSD	ICGC;COSMIC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	Q9BPU6	DPYSL5	P49841	GSK3B	T490	V484F	484	Missense	distal	-6	no	6.275	6.289	EPSD	ICGC;COSMIC	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	Q9BPU6	DPYSL5	P49841	GSK3B	T490	A497S	497	Missense	distal	7	no	6.275	5.927	EPSD	ICGC	6.007	Loss
CMGC_GSK_GSK3B_ST	Q9BPU6	DPYSL5	P49841	GSK3B	T490	G486R	486	Missense	distal	-4	no	6.275	5.516	EPSD	ICGC	6.007	Loss
CMGC_GSK_GSK3B_ST	Q9BPU6	DPYSL5	P49841	GSK3B	T490	P491S	491	Missense	proximal	1	no	6.275	2.430	EPSD	ICGC;COSMIC	6.007	Loss
CMGC_GSK_GSK3B_ST	Q9BPU6	DPYSL5	P49841	GSK3B	T509	T514A	514	Missense	distal	5	no	6.077	6.024	EPSD	ICGC;COSMIC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	Q9BPU6	DPYSL5	P49841	GSK3B	T516	T514A	514	Missense	proximal	-2	no	6.248	5.886	PhosphoSitePlus	ICGC;COSMIC	6.007	Loss
CMGC_GSK_GSK3B_ST	Q9BPU6	DPYSL5	P49841	GSK3B	T516	V519I	519	Missense	distal	3	no	6.248	6.035	PhosphoSitePlus	ICGC;COSMIC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	Q9BPU6	DPYSL5	P49841	GSK3B	T516	R517G	517	Missense	proximal	1	no	6.248	5.374	PhosphoSitePlus	ICGC	6.007	Loss
CMGC_GSK_GSK3B_ST	Q9BPU6	DPYSL5	P49841	GSK3B	T516	G523E	523	Missense	distal	7	no	6.248	6.267	PhosphoSitePlus	ICGC;COSMIC	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	Q9BPU6	DPYSL5	P49841	GSK3B	T516	V519F	519	Missense	distal	3	no	6.248	6.245	PhosphoSitePlus	ICGC;COSMIC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	Q9BPU6	DPYSL5	P49841	GSK3B	T516	R521Q	521	Missense	distal	5	no	6.248	5.909	PhosphoSitePlus	ICGC	6.007	Loss
CMGC_GSK_GSK3B_ST	Q9BPU6	DPYSL5	P49841	GSK3B	S534	E530K	530	Missense	distal	-4	no	7.805	7.537	EPSD	ICGC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	Q9BPU6	DPYSL5	P49841	GSK3B	S534	I540V	540	Missense	distal	6	no	7.805	7.795	EPSD	ICGC;COSMIC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	Q9BPU6	DPYSL5	P49841	GSK3B	S534	S531Y	531	Missense	distal	-3	no	7.805	7.945	EPSD	ICGC;COSMIC	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	Q96F46	IL17RA	P49841	GSK3B	S561	P562Q	562	Missense	proximal	1	no	6.951	3.682	EPSD	ICGC;COSMIC	6.007	Loss
CMGC_GSK_GSK3B_ST	Q96F46	IL17RA	P49841	GSK3B	S561	G564S	564	Missense	distal	3	no	6.951	6.907	EPSD	ICGC;COSMIC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	Q96F46	IL17RA	P49841	GSK3B	S561	L567F	567	Missense	distal	6	no	6.951	6.943	EPSD	ICGC;COSMIC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	Q96F46	IL17RA	P49841	GSK3B	S561	D556E	556	Missense	distal	-5	no	6.951	7.109	EPSD	ICGC;COSMIC	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	Q96F46	IL17RA	P49841	GSK3B	S561	R560W	560	Missense	proximal	-1	no	6.951	7.062	EPSD	ICGC	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	Q96F46	IL17RA	P49841	GSK3B	S708	P704L	704	Missense	distal	-4	no	6.692	5.905	EPSD	ICGC;COSMIC	6.007	Loss
CMGC_GSK_GSK3B_ST	Q96F46	IL17RA	P49841	GSK3B	S708	G707C	707	Missense	proximal	-1	no	6.692	6.649	EPSD	ICGC;COSMIC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	Q96F46	IL17RA	P49841	GSK3B	S731	A735S	735	Missense	distal	4	no	5.946	8.358	EPSD	ICGC	6.007	Gain
CMGC_GSK_GSK3B_ST	Q96F46	IL17RA	P49841	GSK3B	T732	P737A	737	Missense	distal	5	no	7.850	6.821	EPSD	ICGC;COSMIC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	Q96F46	IL17RA	P49841	GSK3B	T732	A735S	735	Missense	distal	3	no	7.850	8.187	EPSD	ICGC	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	Q96F46	IL17RA	P49841	GSK3B	S736	P737A	737	Missense	proximal	1	no	6.973	3.241	EPSD	ICGC;COSMIC	6.007	Loss
CMGC_GSK_GSK3B_ST	Q96F46	IL17RA	P49841	GSK3B	S736	A735S	735	Missense	proximal	-1	no	6.973	7.128	EPSD	ICGC	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	Q96F46	IL17RA	P49841	GSK3B	T780	T780M	780	Missense	central	0	yes	9.209	0.000	PhosphoSitePlus	ICGC;COSMIC	6.007	Loss
CMGC_GSK_GSK3B_ST	Q96F46	IL17RA	P49841	GSK3B	T780	R787W	787	Missense	distal	7	no	9.209	9.318	PhosphoSitePlus	ICGC	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	Q96F46	IL17RA	P49841	GSK3B	S801	S798F	798	Missense	distal	-3	no	7.580	7.647	EPSD	ICGC	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	Q96F46	IL17RA	P49841	GSK3B	S829	P824S	824	Missense	distal	-5	no	7.197	7.354	EPSD	ICGC;COSMIC	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	Q13485	SMAD4	P49841	GSK3B	T9	S5C	5	Missense	distal	-4	no	6.597	4.482	EPSD	ICGC;COSMIC	6.007	Loss
CMGC_GSK_GSK3B_ST	Q13485	SMAD4	P49841	GSK3B	T9	M4L	4	Missense	distal	-5	no	6.597	6.404	EPSD	ICGC;COSMIC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	Q13485	SMAD4	P49841	GSK3B	T9	T11K	11	Missense	proximal	2	no	6.597	6.423	EPSD	ICGC;COSMIC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	Q13485	SMAD4	P49841	GSK3B	S138	Y131S	131	Missense	distal	-7	no	6.678	6.649	EPSD	ICGC;COSMIC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	Q13485	SMAD4	P49841	GSK3B	S138	H132D	132	Missense	distal	-6	no	6.678	6.686	EPSD	ICGC;COSMIC	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	Q13485	SMAD4	P49841	GSK3B	S138	V136A	136	Missense	proximal	-2	no	6.678	6.376	EPSD	ICGC;COSMIC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	Q13485	SMAD4	P49841	GSK3B	S138	R135L	135	Missense	distal	-3	no	6.678	6.518	EPSD	ICGC;COSMIC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	Q13485	SMAD4	P49841	GSK3B	S138	V137L	137	Missense	proximal	-1	no	6.678	6.554	EPSD	ICGC;COSMIC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	Q13485	SMAD4	P49841	GSK3B	S138	Y131C	131	Missense	distal	-7	no	6.678	6.672	EPSD	ICGC;COSMIC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	P01112	HRAS	P49841	GSK3B	T35	R41W	41	Missense	distal	6	no	6.429	6.417	EPSD	ICGC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	P01112	HRAS	P49841	GSK3B	T35	E37D	37	Missense	proximal	2	no	6.429	6.608	EPSD	ICGC;COSMIC	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	P01112	HRAS	P49841	GSK3B	T144	G138R	138	Missense	distal	-6	no	8.137	8.063	EPSD;PhosphoSitePlus	ICGC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	P17661	DES	P49841	GSK3B	S28	P22L	22	Missense	distal	-6	no	8.505	8.483	EPSD;PhosphoSitePlus	ICGC;COSMIC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	P17661	DES	P49841	GSK3B	S28	G27V	27	Missense	proximal	-1	no	8.505	8.547	EPSD;PhosphoSitePlus	ICGC;COSMIC	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	P17661	DES	P49841	GSK3B	S28	P29Q	29	Missense	proximal	1	no	8.505	5.237	EPSD;PhosphoSitePlus	ICGC;COSMIC	6.007	Loss
CMGC_GSK_GSK3B_ST	P17661	DES	P49841	GSK3B	S32	G27V	27	Missense	distal	-5	no	6.826	6.939	PhosphoSitePlus;EPSD	ICGC;COSMIC	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	P17661	DES	P49841	GSK3B	S32	R37L	37	Missense	distal	5	no	6.826	6.183	PhosphoSitePlus;EPSD	ICGC;COSMIC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	P17661	DES	P49841	GSK3B	S32	P29Q	29	Missense	distal	-3	no	6.826	6.972	PhosphoSitePlus;EPSD	ICGC;COSMIC	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	P17661	DES	P49841	GSK3B	S32	P36L	36	Missense	distal	4	no	6.826	7.079	PhosphoSitePlus;EPSD	ICGC;COSMIC	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	P17661	DES	P49841	GSK3B	S42	R37L	37	Missense	distal	-5	no	8.717	8.128	EPSD	ICGC;COSMIC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	P17661	DES	P49841	GSK3B	S42	P36L	36	Missense	distal	-6	no	8.717	8.695	EPSD	ICGC;COSMIC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	P17661	DES	P49841	GSK3B	S46	V53M	53	Missense	distal	7	no	6.402	6.345	EPSD	ICGC;COSMIC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	P17661	DES	P49841	GSK3B	S46	R52H	52	Missense	distal	6	no	6.402	6.397	EPSD	ICGC;COSMIC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	P17661	DES	P49841	GSK3B	T79	G86C	86	Missense	distal	7	no	5.918	6.291	EPSD	ICGC	6.007	Gain
CMGC_GSK_GSK3B_ST	P17661	DES	P49841	GSK3B	S414	R415W	415	Missense	proximal	1	no	5.824	6.041	EPSD	ICGC;GDSC	6.007	Gain
CMGC_GSK_GSK3B_ST	P17661	DES	P49841	GSK3B	S432	P433H	433	Missense	proximal	1	no	7.534	3.834	EPSD	ICGC;COSMIC	6.007	Loss
CMGC_GSK_GSK3B_ST	P17661	DES	P49841	GSK3B	T453	R454W	454	Missense	proximal	1	no	5.968	6.186	EPSD	ICGC;COSMIC	6.007	Gain
CMGC_GSK_GSK3B_ST	P35222	CTNNB1	P49841	GSK3B	S246	L252H	252	Missense	distal	6	no	10.072	10.067	EPSD	ICGC;COSMIC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	P21796	VDAC1	P49841	GSK3B	S241	L242P	242	Missense	proximal	1	no	4.648	7.509	EPSD	ICGC;COSMIC	6.007	Gain
CMGC_GSK_GSK3B_ST	O60346	PHLPP1	P49841	GSK3B	S138	A136T	136	Missense	proximal	-2	no	5.890	6.252	EPSD	ICGC	6.007	Gain
CMGC_GSK_GSK3B_ST	O60346	PHLPP1	P49841	GSK3B	S140	A136T	136	Missense	distal	-4	no	5.458	6.283	EPSD	ICGC	6.007	Gain
CMGC_GSK_GSK3B_ST	O60346	PHLPP1	P49841	GSK3B	S313	V306I	306	Missense	distal	-7	no	9.147	9.153	EPSD	ICGC	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	O60346	PHLPP1	P49841	GSK3B	S336	R338S	338	Missense	proximal	2	no	6.835	6.816	EPSD	ICGC;COSMIC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	O43623	SNAI2	P49841	GSK3B	S54	W59C	59	Missense	distal	5	no	8.846	8.591	EPSD	ICGC;COSMIC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	O43623	SNAI2	P49841	GSK3B	S54	T61N	61	Missense	distal	7	no	8.846	9.028	EPSD	ICGC	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	O43623	SNAI2	P49841	GSK3B	S54	S54R	54	Missense	central	0	yes	8.846	0.000	EPSD	ICGC	6.007	Loss
CMGC_GSK_GSK3B_ST	O43623	SNAI2	P49841	GSK3B	S87	S80F	80	Missense	distal	-7	no	6.504	6.514	EPSD	ICGC;COSMIC	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	O43623	SNAI2	P49841	GSK3B	S87	S81L	81	Missense	distal	-6	no	6.504	6.503	EPSD	ICGC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	O43623	SNAI2	P49841	GSK3B	S92	S95T	95	Missense	distal	3	no	7.260	7.228	EPSD;PhosphoSitePlus	ICGC;COSMIC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	O43623	SNAI2	P49841	GSK3B	S96	S95T	95	Missense	proximal	-1	no	7.461	7.386	EPSD;PhosphoSitePlus	ICGC;COSMIC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	O43623	SNAI2	P49841	GSK3B	S100	S95T	95	Missense	distal	-5	no	7.492	7.781	EPSD;PhosphoSitePlus	ICGC;COSMIC	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	O43623	SNAI2	P49841	GSK3B	S104	E109K	109	Missense	distal	5	no	9.411	8.544	PhosphoSitePlus;EPSD	ICGC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	O43623	SNAI2	P49841	GSK3B	S115	K116R	116	Missense	proximal	1	no	5.409	6.635	EPSD	ICGC	6.007	Gain
CMGC_GSK_GSK3B_ST	O43623	SNAI2	P49841	GSK3B	S247	M253I	253	Missense	distal	6	no	6.713	6.718	EPSD	ICGC;COSMIC	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	P07900	HSP90AA1	P49841	GSK3B	S68	D66Y	66	Missense	proximal	-2	no	6.717	6.413	EPSD	ICGC;COSMIC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	P07900	HSP90AA1	P49841	GSK3B	S68	T65K	65	Missense	distal	-3	no	6.717	6.715	EPSD	ICGC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	P07900	HSP90AA1	P49841	GSK3B	S68	E75V	75	Missense	distal	7	no	6.717	7.103	EPSD	ICGC;COSMIC	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	P07900	HSP90AA1	P49841	GSK3B	S113	A117S	117	Missense	distal	4	no	5.172	7.584	EPSD	ICGC;COSMIC	6.007	Gain
CMGC_GSK_GSK3B_ST	P07900	HSP90AA1	P49841	GSK3B	S673	E668A	668	Missense	distal	-5	no	6.462	6.308	EPSD	ICGC;COSMIC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	P07900	HSP90AA1	P49841	GSK3B	S677	H684R	684	Missense	distal	7	no	6.602	6.414	EPSD	ICGC;COSMIC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	P07900	HSP90AA1	P49841	GSK3B	T704	A710S	710	Missense	distal	6	no	6.072	6.073	EPSD	ICGC;COSMIC	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	P07900	HSP90AA1	P49841	GSK3B	T704	D702G	702	Missense	proximal	-2	no	6.072	5.970	EPSD	ICGC;COSMIC	6.007	Loss
CMGC_GSK_GSK3B_ST	P07900	HSP90AA1	P49841	GSK3B	T704	D701H	701	Missense	distal	-3	no	6.072	6.138	EPSD	ICGC;COSMIC	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	P07900	HSP90AA1	P49841	GSK3B	T704	A705D	705	Missense	proximal	1	no	6.072	6.701	EPSD	ICGC	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	P07900	HSP90AA1	P49841	GSK3B	T704	T708A	708	Missense	distal	4	no	6.072	4.529	EPSD	ICGC	6.007	Loss
CMGC_GSK_GSK3B_ST	P07900	HSP90AA1	P49841	GSK3B	T704	A711V	711	Missense	distal	7	no	6.072	6.149	EPSD	ICGC	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	P07900	HSP90AA1	P49841	GSK3B	S709	A705D	705	Missense	distal	-4	no	5.834	6.393	EPSD	ICGC	6.007	Gain
CMGC_GSK_GSK3B_ST	P07900	HSP90AA1	P49841	GSK3B	T713	P717S	717	Missense	distal	4	no	5.468	8.439	EPSD	ICGC;COSMIC	6.007	Gain
CMGC_GSK_GSK3B_ST	Q9BXF6	RAB11FIP5	P49841	GSK3B	T165	E161K	161	Missense	distal	-4	no	7.251	6.984	EPSD	ICGC;COSMIC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	Q9BXF6	RAB11FIP5	P49841	GSK3B	T165	R159H	159	Missense	distal	-6	no	7.251	7.275	EPSD	ICGC	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	Q9BXF6	RAB11FIP5	P49841	GSK3B	T165	T169M	169	Missense	distal	4	no	7.251	5.885	EPSD	ICGC;COSMIC	6.007	Loss
CMGC_GSK_GSK3B_ST	Q9BXF6	RAB11FIP5	P49841	GSK3B	T165	G160S	160	Missense	distal	-5	no	7.251	6.785	EPSD	ICGC;COSMIC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	Q9BXF6	RAB11FIP5	P49841	GSK3B	T165	R170P	170	Missense	distal	5	no	7.251	7.889	EPSD	ICGC;COSMIC	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	Q9BXF6	RAB11FIP5	P49841	GSK3B	T165	R170S	170	Missense	distal	5	no	7.251	6.935	EPSD	ICGC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	Q9BXF6	RAB11FIP5	P49841	GSK3B	S188	S191R	191	Missense	distal	3	no	6.716	6.346	EPSD;PhosphoSitePlus	ICGC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	Q9BXF6	RAB11FIP5	P49841	GSK3B	S244	R237C	237	Missense	distal	-7	no	6.773	6.777	EPSD	ICGC;COSMIC;CCLE	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	Q9BXF6	RAB11FIP5	P49841	GSK3B	T250	S256N	256	Missense	distal	6	no	6.575	6.569	EPSD	ICGC;COSMIC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	Q9BXF6	RAB11FIP5	P49841	GSK3B	T250	T257N	257	Missense	distal	7	no	6.575	6.757	EPSD	ICGC	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	Q9BXF6	RAB11FIP5	P49841	GSK3B	S256	L258M	258	Missense	proximal	2	no	6.295	5.664	EPSD	ICGC;COSMIC	6.007	Loss
CMGC_GSK_GSK3B_ST	Q9BXF6	RAB11FIP5	P49841	GSK3B	S256	S256N	256	Missense	central	0	yes	6.295	0.000	EPSD	ICGC;COSMIC	6.007	Loss
CMGC_GSK_GSK3B_ST	Q9BXF6	RAB11FIP5	P49841	GSK3B	S256	T257N	257	Missense	proximal	1	no	6.295	3.967	EPSD	ICGC	6.007	Loss
CMGC_GSK_GSK3B_ST	Q9BXF6	RAB11FIP5	P49841	GSK3B	S260	L258M	258	Missense	proximal	-2	no	7.907	7.650	EPSD	ICGC;COSMIC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	Q9BXF6	RAB11FIP5	P49841	GSK3B	S260	S256N	256	Missense	distal	-4	no	7.907	6.610	EPSD	ICGC;COSMIC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	Q9BXF6	RAB11FIP5	P49841	GSK3B	S260	T257N	257	Missense	distal	-3	no	7.907	7.788	EPSD	ICGC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	Q9BXF6	RAB11FIP5	P49841	GSK3B	S260	A266V	266	Missense	distal	6	no	7.907	7.899	EPSD	ICGC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	Q9BXF6	RAB11FIP5	P49841	GSK3B	T276	R281H	281	Missense	distal	5	no	6.143	5.154	PhosphoSitePlus;EPSD	ICGC;COSMIC	6.007	Loss
CMGC_GSK_GSK3B_ST	Q9BXF6	RAB11FIP5	P49841	GSK3B	S278	R281H	281	Missense	distal	3	no	8.421	8.763	EPSD	ICGC;COSMIC	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	Q9BXF6	RAB11FIP5	P49841	GSK3B	S282	R281H	281	Missense	proximal	-1	no	6.182	6.268	EPSD	ICGC;COSMIC	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	Q9BXF6	RAB11FIP5	P49841	GSK3B	S283	R281H	281	Missense	proximal	-2	no	6.743	6.753	EPSD	ICGC;COSMIC	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	Q9BXF6	RAB11FIP5	P49841	GSK3B	S286	S293Y	293	Missense	distal	7	no	5.638	6.080	EPSD	ICGC	6.007	Gain
CMGC_GSK_GSK3B_ST	Q9BXF6	RAB11FIP5	P49841	GSK3B	T305	S307R	307	Missense	proximal	2	no	5.990	6.008	EPSD	ICGC	6.007	Gain
CMGC_GSK_GSK3B_ST	Q9BXF6	RAB11FIP5	P49841	GSK3B	T305	R304M	304	Missense	proximal	-1	no	5.990	6.076	EPSD	ICGC;COSMIC	6.007	Gain
CMGC_GSK_GSK3B_ST	Q9BXF6	RAB11FIP5	P49841	GSK3B	S365	Q369K	369	Missense	distal	4	no	5.916	6.277	EPSD	ICGC;COSMIC	6.007	Gain
CMGC_GSK_GSK3B_ST	Q9BXF6	RAB11FIP5	P49841	GSK3B	S373	Q369K	369	Missense	distal	-4	no	6.129	6.094	EPSD	ICGC;COSMIC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	Q9BXF6	RAB11FIP5	P49841	GSK3B	S391	R392H	392	Missense	proximal	1	no	7.035	5.655	EPSD	ICGC;GDSC;CCLE	6.007	Loss
CMGC_GSK_GSK3B_ST	Q9BXF6	RAB11FIP5	P49841	GSK3B	S473	G471S	471	Missense	proximal	-2	no	5.932	6.049	EPSD	ICGC	6.007	Gain
CMGC_GSK_GSK3B_ST	Q9BXF6	RAB11FIP5	P49841	GSK3B	T519	K516M	516	Missense	distal	-3	no	6.652	6.600	EPSD	ICGC;COSMIC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	Q9BXF6	RAB11FIP5	P49841	GSK3B	S523	K528T	528	Missense	distal	5	no	6.242	6.778	EPSD	ICGC	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	Q9BXF6	RAB11FIP5	P49841	GSK3B	S538	S531T	531	Missense	distal	-7	no	7.258	7.285	EPSD	ICGC;COSMIC	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	Q9BXF6	RAB11FIP5	P49841	GSK3B	S538	R545L	545	Missense	distal	7	no	7.258	6.806	EPSD	ICGC;COSMIC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	Q9BXF6	RAB11FIP5	P49841	GSK3B	S538	P539L	539	Missense	proximal	1	no	7.258	4.398	EPSD	ICGC;COSMIC	6.007	Loss
CMGC_GSK_GSK3B_ST	Q9BXF6	RAB11FIP5	P49841	GSK3B	S641	T643M	643	Missense	proximal	2	no	6.131	5.433	EPSD	ICGC;COSMIC;GDSC;CCLE	6.007	Loss
CMGC_GSK_GSK3B_ST	Q9BXF6	RAB11FIP5	P49841	GSK3B	S641	R636Q	636	Missense	distal	-5	no	6.131	5.576	EPSD	ICGC	6.007	Loss
CMGC_GSK_GSK3B_ST	Q9BXF6	RAB11FIP5	P49841	GSK3B	S641	R636W	636	Missense	distal	-5	no	6.131	5.874	EPSD	ICGC;COSMIC	6.007	Loss
CMGC_GSK_GSK3B_ST	P08047	SP1	P49841	GSK3B	S36	S36L	36	Missense	central	0	yes	6.940	0.000	EPSD	ICGC;COSMIC	6.007	Loss
CMGC_GSK_GSK3B_ST	P08047	SP1	P49841	GSK3B	S36	F35L	35	Missense	proximal	-1	no	6.940	6.995	EPSD	ICGC;COSMIC	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	P08047	SP1	P49841	GSK3B	S41	S36L	36	Missense	distal	-5	no	6.267	6.376	EPSD	ICGC;COSMIC	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	P08047	SP1	P49841	GSK3B	S41	S46C	46	Missense	distal	5	no	6.267	5.027	EPSD	ICGC;COSMIC	6.007	Loss
CMGC_GSK_GSK3B_ST	P08047	SP1	P49841	GSK3B	S41	F35L	35	Missense	distal	-6	no	6.267	6.319	EPSD	ICGC;COSMIC	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	P08047	SP1	P49841	GSK3B	S42	S36L	36	Missense	distal	-6	no	6.374	6.373	EPSD	ICGC;COSMIC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	P08047	SP1	P49841	GSK3B	S42	S46C	46	Missense	distal	4	no	6.374	0.241	EPSD	ICGC;COSMIC	6.007	Loss
CMGC_GSK_GSK3B_ST	P08047	SP1	P49841	GSK3B	S42	F35L	35	Missense	distal	-7	no	6.374	6.364	EPSD	ICGC;COSMIC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	P08047	SP1	P49841	GSK3B	T43	S46C	46	Missense	distal	3	no	6.239	6.023	EPSD	ICGC;COSMIC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	P08047	SP1	P49841	GSK3B	S59	S56A	56	Missense	distal	-3	no	6.846	6.867	EPSD	ICGC;COSMIC	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	P08047	SP1	P49841	GSK3B	S588	Q594E	594	Missense	distal	6	no	7.559	7.557	EPSD	ICGC;COSMIC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	P08047	SP1	P49841	GSK3B	S588	Q592H	592	Missense	distal	4	no	7.559	7.367	EPSD	ICGC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	P08047	SP1	P49841	GSK3B	S588	P589Q	589	Missense	proximal	1	no	7.559	4.291	EPSD	ICGC;COSMIC	6.007	Loss
CMGC_GSK_GSK3B_ST	P08047	SP1	P49841	GSK3B	S735	A738G	738	Missense	distal	3	no	6.564	6.945	EPSD	ICGC;COSMIC	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	P08047	SP1	P49841	GSK3B	T737	A738G	738	Missense	proximal	1	no	6.983	7.521	EPSD	ICGC;COSMIC	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	P08047	SP1	P49841	GSK3B	T739	A738G	738	Missense	proximal	-1	no	7.178	7.340	EPSD	ICGC;COSMIC	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	P08047	SP1	P49841	GSK3B	S741	A738G	738	Missense	distal	-3	no	6.380	6.355	EPSD	ICGC;COSMIC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	P31749	AKT1	P49841	GSK3B	T92	H89R	89	Missense	distal	-3	no	7.359	7.416	EPSD	ICGC	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	P31749	AKT1	P49841	GSK3B	T92	E85K	85	Missense	distal	-7	no	7.359	7.348	EPSD	ICGC;COSMIC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	P31749	AKT1	P49841	GSK3B	T92	R96L	96	Missense	distal	4	no	7.359	7.679	EPSD	ICGC;COSMIC	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	P31749	AKT1	P49841	GSK3B	T312	T305N	305	Missense	distal	-7	no	6.116	6.095	EPSD	ICGC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	P31749	AKT1	P49841	GSK3B	S422	K420T	420	Missense	proximal	-2	no	7.966	8.128	EPSD	ICGC	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	P31749	AKT1	P49841	GSK3B	T450	Q454K	454	Missense	distal	4	no	6.970	7.331	EPSD	ICGC	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	P31749	AKT1	P49841	GSK3B	T450	S457R	457	Missense	distal	7	no	6.970	7.408	EPSD	ICGC	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	P31749	AKT1	P49841	GSK3B	S473	Q471K	471	Missense	proximal	-2	no	6.180	6.091	PhosphoSitePlus;EPSD	ICGC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	P31749	AKT1	P49841	GSK3B	S473	S477R	477	Missense	distal	4	no	6.180	3.142	PhosphoSitePlus;EPSD	ICGC	6.007	Loss
CMGC_GSK_GSK3B_ST	P04637	TP53	P49841	GSK3B	S33	P34L	34	Missense	proximal	1	no	10.252	7.391	EPSD	ICGC;COSMIC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	P04637	TP53	P49841	GSK3B	S33	S33F	33	Missense	central	0	yes	10.252	0.000	EPSD	ICGC;COSMIC	6.007	Loss
CMGC_GSK_GSK3B_ST	P04637	TP53	P49841	GSK3B	S33	N30I	30	Missense	distal	-3	no	10.252	10.460	EPSD	ICGC	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	P04637	TP53	P49841	GSK3B	S46	D48G	48	Missense	proximal	2	no	6.634	6.284	EPSD	ICGC;COSMIC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	P04637	TP53	P49841	GSK3B	S46	Q52K	52	Missense	distal	6	no	6.634	6.632	EPSD	ICGC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	P04637	TP53	P49841	GSK3B	S127	T125R	125	Missense	proximal	-2	no	7.079	6.936	EPSD	ICGC;COSMIC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	P04637	TP53	P49841	GSK3B	S127	F134C	134	Missense	distal	7	no	7.079	7.394	EPSD	ICGC;COSMIC;CCLE	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	P04637	TP53	P49841	GSK3B	S127	C124G	124	Missense	distal	-3	no	7.079	6.972	EPSD	ICGC;COSMIC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	P04637	TP53	P49841	GSK3B	S127	C124R	124	Missense	distal	-3	no	7.079	7.144	EPSD	ICGC;COSMIC;GDSC;CCLE	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	P04637	TP53	P49841	GSK3B	S127	L130H	130	Missense	distal	3	no	7.079	7.351	EPSD	ICGC;COSMIC	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	P04637	TP53	P49841	GSK3B	S127	T125A	125	Missense	proximal	-2	no	7.079	6.717	EPSD	ICGC;COSMIC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	P04637	TP53	P49841	GSK3B	S127	K120N	120	Missense	distal	-7	no	7.079	7.064	EPSD	ICGC;COSMIC;GDSC;CCLE	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	P04637	TP53	P49841	GSK3B	S127	N131Y	131	Missense	distal	4	no	7.079	7.176	EPSD	ICGC;COSMIC	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	P04637	TP53	P49841	GSK3B	S127	K132M	132	Missense	distal	5	no	7.079	7.499	EPSD	ICGC;COSMIC;CCLE	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	P04637	TP53	P49841	GSK3B	S127	M133T	133	Missense	distal	6	no	7.079	7.087	EPSD	ICGC;COSMIC	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	P04637	TP53	P49841	GSK3B	S127	K120R	120	Missense	distal	-7	no	7.079	7.076	EPSD	ICGC;COSMIC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	P04637	TP53	P49841	GSK3B	S127	C124Y	124	Missense	distal	-3	no	7.079	7.116	EPSD	ICGC;COSMIC	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	P04637	TP53	P49841	GSK3B	T150	G154S	154	Missense	distal	4	no	4.205	7.448	EPSD	ICGC;COSMIC	6.007	Gain
CMGC_GSK_GSK3B_ST	P04637	TP53	P49841	GSK3B	T211	F212V	212	Missense	proximal	1	no	5.404	6.644	EPSD	ICGC;COSMIC	6.007	Gain
CMGC_GSK_GSK3B_ST	Q14896	MYBPC3	P49841	GSK3B	S133	A131D	131	Missense	proximal	-2	no	9.246	9.565	EPSD;PhosphoSitePlus	ICGC	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	Q14896	MYBPC3	P49841	GSK3B	S133	G136R	136	Missense	distal	3	no	9.246	8.832	EPSD;PhosphoSitePlus	ICGC;COSMIC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	Q14896	MYBPC3	P49841	GSK3B	T167	R160W	160	Missense	distal	-7	no	7.883	7.892	EPSD	ICGC;COSMIC;GDSC	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	Q14896	MYBPC3	P49841	GSK3B	T167	E165K	165	Missense	proximal	-2	no	7.883	7.851	EPSD	ICGC;COSMIC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	Q14896	MYBPC3	P49841	GSK3B	S171	E165K	165	Missense	distal	-6	no	6.348	6.346	EPSD	ICGC;COSMIC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	Q14896	MYBPC3	P49841	GSK3B	S284	R281W	281	Missense	distal	-3	no	6.574	6.504	EPSD	ICGC;COSMIC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	Q14896	MYBPC3	P49841	GSK3B	S284	R282Q	282	Missense	proximal	-2	no	6.574	6.644	EPSD	ICGC;COSMIC	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	Q14896	MYBPC3	P49841	GSK3B	S284	E288A	288	Missense	distal	4	no	6.574	6.183	EPSD	ICGC;COSMIC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	Q14896	MYBPC3	P49841	GSK3B	S284	G280V	280	Missense	distal	-4	no	6.574	5.768	EPSD	ICGC;COSMIC	6.007	Loss
CMGC_GSK_GSK3B_ST	Q14896	MYBPC3	P49841	GSK3B	S286	R282Q	282	Missense	distal	-4	no	5.663	6.021	EPSD	ICGC;COSMIC	6.007	Gain
CMGC_GSK_GSK3B_ST	Q14896	MYBPC3	P49841	GSK3B	T307	R302K	302	Missense	distal	-5	no	10.058	9.561	EPSD	ICGC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	Q14896	MYBPC3	P49841	GSK3B	S427	A432E	432	Missense	distal	5	no	5.915	6.298	EPSD	ICGC	6.007	Gain
CMGC_GSK_GSK3B_ST	Q14896	MYBPC3	P49841	GSK3B	T607	D610Y	610	Missense	distal	3	no	7.615	7.098	EPSD	ICGC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	Q14896	MYBPC3	P49841	GSK3B	T607	D610E	610	Missense	distal	3	no	7.615	7.500	EPSD	ICGC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	Q14896	MYBPC3	P49841	GSK3B	T607	P608H	608	Missense	proximal	1	no	7.615	3.914	EPSD	ICGC	6.007	Loss
CMGC_GSK_GSK3B_ST	Q14896	MYBPC3	P49841	GSK3B	T607	D605N	605	Missense	proximal	-2	no	7.615	7.402	EPSD	ICGC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	Q14896	MYBPC3	P49841	GSK3B	S1067	P1069T	1069	Missense	proximal	2	no	9.012	8.695	EPSD	ICGC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	Q14896	MYBPC3	P49841	GSK3B	S1067	P1066T	1066	Missense	proximal	-1	no	9.012	8.881	EPSD	ICGC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	Q14896	MYBPC3	P49841	GSK3B	S1067	L1072P	1072	Missense	distal	5	no	9.012	10.293	EPSD	ICGC;COSMIC	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	Q01094	E2F1	P49841	GSK3B	S121	S121F	121	Missense	central	0	yes	6.711	0.000	EPSD	ICGC;COSMIC;CCLE	6.007	Loss
CMGC_GSK_GSK3B_ST	Q01094	E2F1	P49841	GSK3B	S121	P122L	122	Missense	proximal	1	no	6.711	3.850	EPSD	ICGC	6.007	Loss
CMGC_GSK_GSK3B_ST	Q01094	E2F1	P49841	GSK3B	S131	R138H	138	Missense	distal	7	no	6.065	6.253	EPSD	ICGC;COSMIC	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	Q01094	E2F1	P49841	GSK3B	S307	P308T	308	Missense	proximal	1	no	8.116	4.925	EPSD	ICGC	6.007	Loss
CMGC_GSK_GSK3B_ST	Q01094	E2F1	P49841	GSK3B	S307	G305W	305	Missense	proximal	-2	no	8.116	8.324	EPSD	ICGC;COSMIC	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	Q01094	E2F1	P49841	GSK3B	S307	G305V	305	Missense	proximal	-2	no	8.116	8.201	EPSD	ICGC;COSMIC	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	Q01094	E2F1	P49841	GSK3B	T311	P308T	308	Missense	distal	-3	no	7.138	7.280	EPSD	ICGC	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	Q01094	E2F1	P49841	GSK3B	T311	G305W	305	Missense	distal	-6	no	7.138	7.092	EPSD	ICGC;COSMIC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	Q01094	E2F1	P49841	GSK3B	T311	S318A	318	Missense	distal	7	no	7.138	7.486	EPSD	ICGC	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	Q01094	E2F1	P49841	GSK3B	T311	G305V	305	Missense	distal	-6	no	7.138	7.055	EPSD	ICGC;COSMIC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	Q01094	E2F1	P49841	GSK3B	S313	P308T	308	Missense	distal	-5	no	6.819	7.265	EPSD	ICGC	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	Q01094	E2F1	P49841	GSK3B	S313	S318A	318	Missense	distal	5	no	6.819	6.744	EPSD	ICGC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	Q01094	E2F1	P49841	GSK3B	S375	V369M	369	Missense	distal	-6	no	6.762	6.777	EPSD	ICGC	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	Q01094	E2F1	P49841	GSK3B	S403	A408V	408	Missense	distal	5	no	9.524	9.097	EPSD;PhosphoSitePlus	ICGC;COSMIC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	Q01094	E2F1	P49841	GSK3B	S403	E397K	397	Missense	distal	-6	no	9.524	9.523	EPSD;PhosphoSitePlus	ICGC;COSMIC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	Q15746	MYLK	P49841	GSK3B	S18	P21H	21	Missense	distal	3	no	8.033	7.986	EPSD	ICGC;COSMIC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	Q15746	MYLK	P49841	GSK3B	S18	R23T	23	Missense	distal	5	no	8.033	7.694	EPSD	ICGC;COSMIC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	Q15746	MYLK	P49841	GSK3B	S18	P21S	21	Missense	distal	3	no	8.033	8.015	EPSD	ICGC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	Q15746	MYLK	P49841	GSK3B	S305	S299I	299	Missense	distal	-6	no	6.725	6.662	EPSD	ICGC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	Q15746	MYLK	P49841	GSK3B	S305	S312R	312	Missense	distal	7	no	6.725	7.163	EPSD	ICGC	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	Q15746	MYLK	P49841	GSK3B	S328	Q334H	334	Missense	distal	6	no	9.091	9.084	EPSD	ICGC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	Q15746	MYLK	P49841	GSK3B	T335	T341S	341	Missense	distal	6	no	6.367	6.364	EPSD	ICGC;COSMIC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	Q15746	MYLK	P49841	GSK3B	T335	Q334H	334	Missense	proximal	-1	no	6.367	6.422	EPSD	ICGC	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	Q15746	MYLK	P49841	GSK3B	S365	P359Q	359	Missense	distal	-6	no	8.153	8.128	EPSD	ICGC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	Q15746	MYLK	P49841	GSK3B	S365	A358E	358	Missense	distal	-7	no	8.153	8.164	EPSD	ICGC	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	Q15746	MYLK	P49841	GSK3B	S391	G388D	388	Missense	distal	-3	no	6.467	6.518	EPSD	ICGC;COSMIC	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	Q15746	MYLK	P49841	GSK3B	S947	E942Q	942	Missense	distal	-5	no	7.383	7.095	EPSD	ICGC;COSMIC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	Q15746	MYLK	P49841	GSK3B	S947	R954S	954	Missense	distal	7	no	7.383	6.945	EPSD	ICGC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	Q15746	MYLK	P49841	GSK3B	S947	E941K	941	Missense	distal	-6	no	7.383	7.382	EPSD	ICGC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	Q15746	MYLK	P49841	GSK3B	S1093	A1097D	1097	Missense	distal	4	no	6.013	6.001	EPSD	ICGC	6.007	Loss
CMGC_GSK_GSK3B_ST	Q15746	MYLK	P49841	GSK3B	T1230	K1233T	1233	Missense	distal	3	no	7.083	7.177	EPSD	ICGC;COSMIC	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	Q15746	MYLK	P49841	GSK3B	T1230	P1228H	1228	Missense	proximal	-2	no	7.083	6.722	EPSD	ICGC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	Q15746	MYLK	P49841	GSK3B	T1230	P1232T	1232	Missense	proximal	2	no	7.083	6.766	EPSD	ICGC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	Q15746	MYLK	P49841	GSK3B	T1230	T1230K	1230	Missense	central	0	yes	7.083	0.000	EPSD	ICGC	6.007	Loss
CMGC_GSK_GSK3B_ST	Q15746	MYLK	P49841	GSK3B	T1230	M1236V	1236	Missense	distal	6	no	7.083	7.079	EPSD	ICGC;COSMIC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	Q15746	MYLK	P49841	GSK3B	T1337	P1334L	1334	Missense	distal	-3	no	10.713	10.839	EPSD	ICGC	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	Q15746	MYLK	P49841	GSK3B	T1337	P1331T	1331	Missense	distal	-6	no	10.713	10.634	EPSD	ICGC;COSMIC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	Q15746	MYLK	P49841	GSK3B	T1337	G1336D	1336	Missense	proximal	-1	no	10.713	10.646	EPSD	ICGC;COSMIC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	Q15746	MYLK	P49841	GSK3B	S1419	S1416N	1416	Missense	distal	-3	no	6.665	6.571	EPSD	ICGC;COSMIC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	Q15746	MYLK	P49841	GSK3B	T1624	F1622S	1622	Missense	proximal	-2	no	6.305	6.635	EPSD	ICGC	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	Q15746	MYLK	P49841	GSK3B	T1624	F1622V	1622	Missense	proximal	-2	no	6.305	6.603	EPSD	ICGC	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	Q15746	MYLK	P49841	GSK3B	S1659	M1662V	1662	Missense	distal	3	no	8.263	8.246	EPSD	ICGC;COSMIC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	P20393	NR1D1	P49841	GSK3B	S55	P54T	54	Missense	proximal	-1	no	10.392	10.260	PhosphoSitePlus;EPSD	ICGC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	P20393	NR1D1	P49841	GSK3B	S59	R66C	66	Missense	distal	7	no	6.607	6.562	EPSD;PhosphoSitePlus	ICGC;COSMIC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	P20393	NR1D1	P49841	GSK3B	S59	P54T	54	Missense	distal	-5	no	6.607	7.053	EPSD;PhosphoSitePlus	ICGC	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	P20393	NR1D1	P49841	GSK3B	S84	D78N	78	Missense	distal	-6	no	7.876	7.899	EPSD	ICGC;COSMIC	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	P20393	NR1D1	P49841	GSK3B	S84	S87L	87	Missense	distal	3	no	7.876	7.576	EPSD	ICGC;COSMIC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	P20393	NR1D1	P49841	GSK3B	S86	S87L	87	Missense	proximal	1	no	6.187	7.171	EPSD	ICGC;COSMIC	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	P20393	NR1D1	P49841	GSK3B	S87	S87L	87	Missense	central	0	yes	7.104	0.000	EPSD	ICGC;COSMIC	6.007	Loss
CMGC_GSK_GSK3B_ST	P20393	NR1D1	P49841	GSK3B	S278	P283A	283	Missense	distal	5	no	11.121	10.092	EPSD	ICGC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	P20393	NR1D1	P49841	GSK3B	S280	P283A	283	Missense	distal	3	no	7.768	7.413	EPSD	ICGC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	P20393	NR1D1	P49841	GSK3B	S309	S310P	310	Missense	proximal	1	no	3.014	6.859	EPSD	ICGC;COSMIC	6.007	Gain
CMGC_GSK_GSK3B_ST	P20393	NR1D1	P49841	GSK3B	T326	R330S	330	Missense	distal	4	no	5.222	8.260	EPSD	ICGC;COSMIC	6.007	Gain
CMGC_GSK_GSK3B_ST	Q9UKT5	FBXO4	P49841	GSK3B	S8	E5K	5	Missense	distal	-3	no	7.416	7.427	EPSD	ICGC	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	Q9UKT5	FBXO4	P49841	GSK3B	S8	S8R	8	Missense	central	0	yes	7.416	0.000	EPSD	ICGC	6.007	Loss
CMGC_GSK_GSK3B_ST	Q9UKT5	FBXO4	P49841	GSK3B	S8	T10K	10	Missense	proximal	2	no	7.416	7.243	EPSD	ICGC;COSMIC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	Q9UKT5	FBXO4	P49841	GSK3B	S12	E5K	5	Missense	distal	-7	no	8.279	8.268	PhosphoSitePlus	ICGC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	Q9UKT5	FBXO4	P49841	GSK3B	S12	S8R	8	Missense	distal	-4	no	8.279	7.092	PhosphoSitePlus	ICGC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	Q9UKT5	FBXO4	P49841	GSK3B	S12	T10K	10	Missense	proximal	-2	no	8.279	8.117	PhosphoSitePlus	ICGC;COSMIC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	Q9NYF8	BCLAF1	P49841	GSK3B	S15	S19F	19	Missense	distal	4	no	7.933	4.319	EPSD	ICGC;COSMIC	6.007	Loss
CMGC_GSK_GSK3B_ST	Q9NYF8	BCLAF1	P49841	GSK3B	S15	R22G	22	Missense	distal	7	no	7.933	7.515	EPSD	ICGC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	Q9NYF8	BCLAF1	P49841	GSK3B	S19	S19F	19	Missense	central	0	yes	7.212	0.000	EPSD	ICGC;COSMIC	6.007	Loss
CMGC_GSK_GSK3B_ST	Q9NYF8	BCLAF1	P49841	GSK3B	S19	R22G	22	Missense	distal	3	no	7.212	7.627	EPSD	ICGC	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	Q9NYF8	BCLAF1	P49841	GSK3B	S44	R51S	51	Missense	distal	7	no	8.536	8.098	EPSD	ICGC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	Q9NYF8	BCLAF1	P49841	GSK3B	S46	R51S	51	Missense	distal	5	no	6.579	6.263	EPSD	ICGC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	Q9NYF8	BCLAF1	P49841	GSK3B	S48	R51S	51	Missense	distal	3	no	6.141	6.512	EPSD	ICGC	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	Q9NYF8	BCLAF1	P49841	GSK3B	S54	R59H	59	Missense	distal	5	no	6.057	5.068	EPSD	ICGC	6.007	Loss
CMGC_GSK_GSK3B_ST	Q9NYF8	BCLAF1	P49841	GSK3B	S54	R51S	51	Missense	distal	-3	no	6.057	5.889	EPSD	ICGC	6.007	Loss
CMGC_GSK_GSK3B_ST	Q9NYF8	BCLAF1	P49841	GSK3B	S104	R109H	109	Missense	distal	5	no	7.978	6.989	EPSD	ICGC;COSMIC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	Q9NYF8	BCLAF1	P49841	GSK3B	S114	S112Y	112	Missense	proximal	-2	no	7.790	7.470	EPSD	ICGC;COSMIC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	Q9NYF8	BCLAF1	P49841	GSK3B	S114	R109H	109	Missense	distal	-5	no	7.790	7.259	EPSD	ICGC;COSMIC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	Q9NYF8	BCLAF1	P49841	GSK3B	S121	R128H	128	Missense	distal	7	no	7.333	7.521	EPSD	ICGC;COSMIC	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	Q9NYF8	BCLAF1	P49841	GSK3B	S121	R126T	126	Missense	distal	5	no	7.333	6.994	EPSD	ICGC;COSMIC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	Q9NYF8	BCLAF1	P49841	GSK3B	S121	R124I	124	Missense	distal	3	no	7.333	7.284	EPSD	ICGC;GDSC;CCLE	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	Q9NYF8	BCLAF1	P49841	GSK3B	S125	R128H	128	Missense	distal	3	no	8.877	9.219	EPSD	ICGC;COSMIC	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	Q9NYF8	BCLAF1	P49841	GSK3B	S125	R130C	130	Missense	distal	5	no	8.877	7.321	EPSD	ICGC;COSMIC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	Q9NYF8	BCLAF1	P49841	GSK3B	S125	R126T	126	Missense	proximal	1	no	8.877	8.006	EPSD	ICGC;COSMIC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	Q9NYF8	BCLAF1	P49841	GSK3B	S125	R124I	124	Missense	proximal	-1	no	8.877	8.865	EPSD	ICGC;GDSC;CCLE	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	Q9NYF8	BCLAF1	P49841	GSK3B	S138	S135Y	135	Missense	distal	-3	no	10.710	10.850	EPSD	ICGC;COSMIC	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	Q9NYF8	BCLAF1	P49841	GSK3B	S138	S142A	142	Missense	distal	4	no	10.710	8.298	EPSD	ICGC;COSMIC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	Q9NYF8	BCLAF1	P49841	GSK3B	S143	S146T	146	Missense	distal	3	no	6.597	6.565	EPSD	ICGC;COSMIC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	Q9NYF8	BCLAF1	P49841	GSK3B	S143	S146Y	146	Missense	distal	3	no	6.597	6.175	EPSD	ICGC;COSMIC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	Q9NYF8	BCLAF1	P49841	GSK3B	S143	S148F	148	Missense	distal	5	no	6.597	5.930	EPSD	ICGC	6.007	Loss
CMGC_GSK_GSK3B_ST	Q9NYF8	BCLAF1	P49841	GSK3B	S143	S146F	146	Missense	distal	3	no	6.597	6.387	EPSD	ICGC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	Q9NYF8	BCLAF1	P49841	GSK3B	S143	S142A	142	Missense	proximal	-1	no	6.597	6.443	EPSD	ICGC;COSMIC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	Q9NYF8	BCLAF1	P49841	GSK3B	S147	S146T	146	Missense	proximal	-1	no	6.286	6.211	EPSD	ICGC;COSMIC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	Q9NYF8	BCLAF1	P49841	GSK3B	S147	S146Y	146	Missense	proximal	-1	no	6.286	6.146	EPSD	ICGC;COSMIC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	Q9NYF8	BCLAF1	P49841	GSK3B	S147	S148F	148	Missense	proximal	1	no	6.286	5.900	EPSD	ICGC	6.007	Loss
CMGC_GSK_GSK3B_ST	Q9NYF8	BCLAF1	P49841	GSK3B	S147	S146F	146	Missense	proximal	-1	no	6.286	6.155	EPSD	ICGC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	Q9NYF8	BCLAF1	P49841	GSK3B	S147	S142A	142	Missense	distal	-5	no	6.286	6.563	EPSD	ICGC;COSMIC	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	Q9NYF8	BCLAF1	P49841	GSK3B	S148	S146T	146	Missense	proximal	-2	no	7.086	7.113	EPSD	ICGC;COSMIC	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	Q9NYF8	BCLAF1	P49841	GSK3B	S148	S146Y	146	Missense	proximal	-2	no	7.086	6.767	EPSD	ICGC;COSMIC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	Q9NYF8	BCLAF1	P49841	GSK3B	S148	S148F	148	Missense	central	0	yes	7.086	0.000	EPSD	ICGC	6.007	Loss
CMGC_GSK_GSK3B_ST	Q9NYF8	BCLAF1	P49841	GSK3B	S148	S146F	146	Missense	proximal	-2	no	7.086	6.756	EPSD	ICGC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	Q9NYF8	BCLAF1	P49841	GSK3B	S148	S142A	142	Missense	distal	-6	no	7.086	7.097	EPSD	ICGC;COSMIC	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	Q9NYF8	BCLAF1	P49841	GSK3B	S153	S146T	146	Missense	distal	-7	no	7.955	7.981	EPSD	ICGC;COSMIC	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	Q9NYF8	BCLAF1	P49841	GSK3B	S153	S146Y	146	Missense	distal	-7	no	7.955	7.983	EPSD	ICGC;COSMIC	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	Q9NYF8	BCLAF1	P49841	GSK3B	S153	S148F	148	Missense	distal	-5	no	7.955	8.514	EPSD	ICGC	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	Q9NYF8	BCLAF1	P49841	GSK3B	S153	S146F	146	Missense	distal	-7	no	7.955	7.965	EPSD	ICGC	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	Q9NYF8	BCLAF1	P49841	GSK3B	S205	S209C	209	Missense	distal	4	no	6.387	0.254	EPSD	ICGC;COSMIC	6.007	Loss
CMGC_GSK_GSK3B_ST	Q9NYF8	BCLAF1	P49841	GSK3B	S205	K204R	204	Missense	proximal	-1	no	6.387	6.194	EPSD	ICGC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	Q9NYF8	BCLAF1	P49841	GSK3B	S222	P223R	223	Missense	proximal	1	no	6.497	4.177	EPSD	ICGC;COSMIC	6.007	Loss
CMGC_GSK_GSK3B_ST	Q9NYF8	BCLAF1	P49841	GSK3B	S222	D220Y	220	Missense	proximal	-2	no	6.497	6.193	EPSD	ICGC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	Q9NYF8	BCLAF1	P49841	GSK3B	S225	P223R	223	Missense	proximal	-2	no	6.242	5.870	EPSD	ICGC;COSMIC	6.007	Loss
CMGC_GSK_GSK3B_ST	Q9NYF8	BCLAF1	P49841	GSK3B	S225	D220Y	220	Missense	distal	-5	no	6.242	6.622	EPSD	ICGC	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	Q9NYF8	BCLAF1	P49841	GSK3B	S228	P235Q	235	Missense	distal	7	no	7.154	7.308	EPSD	ICGC;COSMIC	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	Q9NYF8	BCLAF1	P49841	GSK3B	S228	P223R	223	Missense	distal	-5	no	7.154	8.008	EPSD	ICGC;COSMIC	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	Q9NYF8	BCLAF1	P49841	GSK3B	S230	P235Q	235	Missense	distal	5	no	8.932	7.956	EPSD	ICGC;COSMIC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	Q9NYF8	BCLAF1	P49841	GSK3B	S230	P223R	223	Missense	distal	-7	no	8.932	8.952	EPSD	ICGC;COSMIC	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	Q9NYF8	BCLAF1	P49841	GSK3B	S239	P235Q	235	Missense	distal	-4	no	6.553	6.287	EPSD	ICGC;COSMIC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	Q9NYF8	BCLAF1	P49841	GSK3B	S239	Q238K	238	Missense	proximal	-1	no	6.553	6.715	EPSD	ICGC;COSMIC	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	Q9NYF8	BCLAF1	P49841	GSK3B	S239	S241Y	241	Missense	proximal	2	no	6.553	6.321	EPSD	ICGC;COSMIC;GDSC;CCLE	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	Q9NYF8	BCLAF1	P49841	GSK3B	S264	S262F	262	Missense	proximal	-2	no	7.837	7.507	EPSD	ICGC;COSMIC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	Q9NYF8	BCLAF1	P49841	GSK3B	S268	S272F	272	Missense	distal	4	no	8.909	5.294	EPSD	ICGC;COSMIC	6.007	Loss
CMGC_GSK_GSK3B_ST	Q9NYF8	BCLAF1	P49841	GSK3B	S268	S262F	262	Missense	distal	-6	no	8.909	8.855	EPSD	ICGC;COSMIC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	Q9NYF8	BCLAF1	P49841	GSK3B	S272	S272F	272	Missense	central	0	yes	7.067	0.000	EPSD	ICGC;COSMIC	6.007	Loss
CMGC_GSK_GSK3B_ST	Q9NYF8	BCLAF1	P49841	GSK3B	S272	G278R	278	Missense	distal	6	no	7.067	7.066	EPSD	ICGC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	Q9NYF8	BCLAF1	P49841	GSK3B	S281	S281Y	281	Missense	central	0	yes	6.424	0.000	EPSD	ICGC;COSMIC	6.007	Loss
CMGC_GSK_GSK3B_ST	Q9NYF8	BCLAF1	P49841	GSK3B	S281	G278R	278	Missense	distal	-3	no	6.424	6.597	EPSD	ICGC	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	Q9NYF8	BCLAF1	P49841	GSK3B	S285	S281Y	281	Missense	distal	-4	no	7.515	6.714	EPSD	ICGC;COSMIC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	Q9NYF8	BCLAF1	P49841	GSK3B	S285	G278R	278	Missense	distal	-7	no	7.515	7.535	EPSD	ICGC	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	Q9NYF8	BCLAF1	P49841	GSK3B	S300	S297L	297	Missense	distal	-3	no	8.714	8.723	EPSD	ICGC	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	Q9NYF8	BCLAF1	P49841	GSK3B	S300	H293Y	293	Missense	distal	-7	no	8.714	8.724	EPSD	ICGC	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	Q9NYF8	BCLAF1	P49841	GSK3B	S714	G709V	709	Missense	distal	-5	no	8.636	8.749	EPSD	ICGC;COSMIC	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	Q9NYF8	BCLAF1	P49841	GSK3B	S749	S752F	752	Missense	distal	3	no	7.933	7.722	EPSD	ICGC;COSMIC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	Q9NYF8	BCLAF1	P49841	GSK3B	S751	S757F	757	Missense	distal	6	no	7.694	7.682	EPSD	ICGC;COSMIC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	Q9NYF8	BCLAF1	P49841	GSK3B	S751	S752F	752	Missense	proximal	1	no	7.694	7.308	EPSD	ICGC;COSMIC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	Q9NYF8	BCLAF1	P49841	GSK3B	S755	S757F	757	Missense	proximal	2	no	7.502	7.158	EPSD	ICGC;COSMIC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	Q9NYF8	BCLAF1	P49841	GSK3B	S755	S752F	752	Missense	distal	-3	no	7.502	7.569	EPSD	ICGC;COSMIC	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	Q9NYF8	BCLAF1	P49841	GSK3B	S757	S757F	757	Missense	central	0	yes	8.512	0.000	EPSD	ICGC;COSMIC	6.007	Loss
CMGC_GSK_GSK3B_ST	Q9NYF8	BCLAF1	P49841	GSK3B	S757	S752F	752	Missense	distal	-5	no	8.512	9.072	EPSD	ICGC;COSMIC	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	Q9NYF8	BCLAF1	P49841	GSK3B	S759	S757F	757	Missense	proximal	-2	no	7.745	7.415	EPSD	ICGC;COSMIC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	Q9NYF8	BCLAF1	P49841	GSK3B	S759	S752F	752	Missense	distal	-7	no	7.745	7.756	EPSD	ICGC;COSMIC	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	Q9NYF8	BCLAF1	P49841	GSK3B	S760	S757F	757	Missense	distal	-3	no	7.612	7.679	EPSD	ICGC;COSMIC	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	O75030	MITF	P49841	GSK3B	S405	L404F	404	Missense	proximal	-1	no	6.770	6.715	EPSD;PhosphoSitePlus	ICGC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	O75030	MITF	P49841	GSK3B	S405	L404P	404	Missense	proximal	-1	no	6.770	6.901	EPSD;PhosphoSitePlus	ICGC;COSMIC	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	O75030	MITF	P49841	GSK3B	S405	R400Q	400	Missense	distal	-5	no	6.770	6.216	EPSD;PhosphoSitePlus	ICGC;COSMIC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	O75030	MITF	P49841	GSK3B	S414	R420W	420	Missense	distal	6	no	7.354	7.343	EPSD	ICGC;COSMIC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	O75030	MITF	P49841	GSK3B	S414	D416N	416	Missense	proximal	2	no	7.354	6.731	EPSD	ICGC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	O75030	MITF	P49841	GSK3B	S491	G494D	494	Missense	distal	3	no	6.724	6.775	EPSD	ICGC;COSMIC	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	O75030	MITF	P49841	GSK3B	S491	D488N	488	Missense	distal	-3	no	6.724	6.583	EPSD	ICGC;COSMIC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	O75030	MITF	P49841	GSK3B	S491	T496N	496	Missense	distal	5	no	6.724	6.426	EPSD	ICGC;COSMIC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	O75030	MITF	P49841	GSK3B	S491	D488G	488	Missense	distal	-3	no	6.724	6.674	EPSD	ICGC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	O75030	MITF	P49841	GSK3B	S491	L490F	490	Missense	proximal	-1	no	6.724	6.668	EPSD	ICGC;COSMIC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	O75030	MITF	P49841	GSK3B	S491	D497G	497	Missense	distal	6	no	6.724	6.728	EPSD	ICGC;COSMIC	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	O75030	MITF	P49841	GSK3B	S504	G506R	506	Missense	proximal	2	no	9.447	9.724	EPSD	ICGC;COSMIC	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	O75030	MITF	P49841	GSK3B	S504	S504C	504	Missense	central	0	yes	9.447	0.000	EPSD	ICGC;COSMIC	6.007	Loss
CMGC_GSK_GSK3B_ST	O75030	MITF	P49841	GSK3B	S504	S504P	504	Missense	central	0	yes	9.447	0.000	EPSD	ICGC	6.007	Loss
CMGC_GSK_GSK3B_ST	O75030	MITF	P49841	GSK3B	S504	D497G	497	Missense	distal	-7	no	9.447	9.442	EPSD	ICGC;COSMIC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	O75030	MITF	P49841	GSK3B	S504	L500F	500	Missense	distal	-4	no	9.447	9.643	EPSD	ICGC;COSMIC	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	O75030	MITF	P49841	GSK3B	S508	G506R	506	Missense	proximal	-2	no	7.924	7.926	EPSD	ICGC;COSMIC	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	O75030	MITF	P49841	GSK3B	S508	S504C	504	Missense	distal	-4	no	7.924	5.810	EPSD	ICGC;COSMIC	6.007	Loss
CMGC_GSK_GSK3B_ST	O75030	MITF	P49841	GSK3B	S508	S504P	504	Missense	distal	-4	no	7.924	7.361	EPSD	ICGC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	O75030	MITF	P49841	GSK3B	S508	R513Q	513	Missense	distal	5	no	7.924	7.585	EPSD	ICGC;COSMIC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	O75030	MITF	P49841	GSK3B	S511	G506R	506	Missense	distal	-5	no	6.054	6.285	EPSD	ICGC;COSMIC	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	O75030	MITF	P49841	GSK3B	S511	S504C	504	Missense	distal	-7	no	6.054	6.077	EPSD	ICGC;COSMIC	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	O75030	MITF	P49841	GSK3B	S511	S504P	504	Missense	distal	-7	no	6.054	6.052	EPSD	ICGC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	O75030	MITF	P49841	GSK3B	S511	R513Q	513	Missense	proximal	2	no	6.054	6.259	EPSD	ICGC;COSMIC	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	O75030	MITF	P49841	GSK3B	S512	G506R	506	Missense	distal	-6	no	9.465	9.392	EPSD	ICGC;COSMIC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	O75030	MITF	P49841	GSK3B	S512	M519T	519	Missense	distal	7	no	9.465	9.038	EPSD	ICGC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	O75030	MITF	P49841	GSK3B	S512	R513Q	513	Missense	proximal	1	no	9.465	8.517	EPSD	ICGC;COSMIC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	O75030	MITF	P49841	GSK3B	S515	M519T	519	Missense	distal	4	no	4.721	6.087	EPSD	ICGC	6.007	Gain
CMGC_GSK_GSK3B_ST	O75030	MITF	P49841	GSK3B	S518	E523K	523	Missense	distal	5	no	6.269	5.402	EPSD	ICGC;COSMIC	6.007	Loss
CMGC_GSK_GSK3B_ST	O75030	MITF	P49841	GSK3B	S518	M519T	519	Missense	proximal	1	no	6.269	6.665	EPSD	ICGC	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	O75030	MITF	P49841	GSK3B	S518	R513Q	513	Missense	distal	-5	no	6.269	5.714	EPSD	ICGC;COSMIC	6.007	Loss
CMGC_GSK_GSK3B_ST	P48436	SOX9	P49841	GSK3B	S19	E13K	13	Missense	distal	-6	no	9.328	9.327	EPSD	ICGC;COSMIC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	P48436	SOX9	P49841	GSK3B	S19	P22T	22	Missense	distal	3	no	9.328	9.277	EPSD	ICGC;COSMIC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	P48436	SOX9	P49841	GSK3B	S23	P22T	22	Missense	proximal	-1	no	9.576	9.444	EPSD	ICGC;COSMIC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	P48436	SOX9	P49841	GSK3B	S33	C35F	35	Missense	proximal	2	no	8.960	9.107	EPSD	ICGC;COSMIC	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	P48436	SOX9	P49841	GSK3B	S37	C35F	35	Missense	proximal	-2	no	8.222	8.203	EPSD	ICGC;COSMIC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	P48436	SOX9	P49841	GSK3B	S211	A209V	209	Missense	proximal	-2	no	8.253	8.555	EPSD	ICGC;COSMIC	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	P48436	SOX9	P49841	GSK3B	S211	G217V	217	Missense	distal	6	no	8.253	8.246	EPSD	ICGC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	P48436	SOX9	P49841	GSK3B	S215	A209V	209	Missense	distal	-6	no	7.687	7.610	EPSD	ICGC;COSMIC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	P48436	SOX9	P49841	GSK3B	S215	G217V	217	Missense	proximal	2	no	7.687	7.677	EPSD	ICGC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	P48436	SOX9	P49841	GSK3B	S219	G217V	217	Missense	proximal	-2	no	6.894	6.979	EPSD	ICGC	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	P48436	SOX9	P49841	GSK3B	S223	G217V	217	Missense	distal	-6	no	8.263	8.180	EPSD	ICGC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	P48436	SOX9	P49841	GSK3B	S488	G485V	485	Missense	distal	-3	no	6.552	6.723	EPSD	ICGC;COSMIC	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	P06401	PGR	P49841	GSK3B	S88	G85V	85	Missense	distal	-3	no	5.920	6.092	EPSD	ICGC	6.007	Gain
CMGC_GSK_GSK3B_ST	P06401	PGR	P49841	GSK3B	S162	S168Y	168	Missense	distal	6	no	11.146	11.140	EPSD	ICGC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	P06401	PGR	P49841	GSK3B	S162	L164I	164	Missense	proximal	2	no	11.146	11.147	EPSD	ICGC	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	P06401	PGR	P49841	GSK3B	S213	A208T	208	Missense	distal	-5	no	6.936	6.947	EPSD	ICGC;COSMIC	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	P06401	PGR	P49841	GSK3B	S213	G207R	207	Missense	distal	-6	no	6.936	6.862	EPSD	ICGC;GDSC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	P06401	PGR	P49841	GSK3B	S273	E271D	271	Missense	proximal	-2	no	6.161	6.248	EPSD	ICGC;COSMIC	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	P06401	PGR	P49841	GSK3B	S273	F275L	275	Missense	proximal	2	no	6.161	6.565	EPSD	ICGC;COSMIC	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	P06401	PGR	P49841	GSK3B	S294	T299M	299	Missense	distal	5	no	9.431	9.315	EPSD	ICGC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	P06401	PGR	P49841	GSK3B	S294	P291L	291	Missense	distal	-3	no	9.431	9.558	EPSD	ICGC;COSMIC	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	P06401	PGR	P49841	GSK3B	S294	A287T	287	Missense	distal	-7	no	9.431	9.436	EPSD	ICGC;GDSC;CCLE	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	P06401	PGR	P49841	GSK3B	S345	R343W	343	Missense	proximal	-2	no	9.402	9.608	EPSD	ICGC;COSMIC	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	P06401	PGR	P49841	GSK3B	S345	P341L	341	Missense	distal	-4	no	9.402	8.616	EPSD	ICGC;COSMIC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	P06401	PGR	P49841	GSK3B	S345	P341T	341	Missense	distal	-4	no	9.402	9.630	EPSD	ICGC;COSMIC	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	P06401	PGR	P49841	GSK3B	S345	P352Q	352	Missense	distal	7	no	9.402	9.556	EPSD	ICGC;COSMIC	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	P06401	PGR	P49841	GSK3B	T351	P352Q	352	Missense	proximal	1	no	7.159	3.891	EPSD	ICGC;COSMIC	6.007	Loss
CMGC_GSK_GSK3B_ST	P06401	PGR	P49841	GSK3B	S554	E560D	560	Missense	distal	6	no	10.722	10.721	EPSD	ICGC;COSMIC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	P06401	PGR	P49841	GSK3B	S554	P555Q	555	Missense	proximal	1	no	10.722	7.454	EPSD	ICGC;COSMIC;GDSC;CCLE	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	Q9NRD5	PICK1	P49841	GSK3B	S411	P405S	405	Missense	distal	-6	no	6.750	6.730	EPSD	ICGC;COSMIC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	O75952	CABYR	P49841	GSK3B	T75	T74M	74	Missense	proximal	-1	no	7.069	7.094	EPSD	ICGC;COSMIC	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	O75952	CABYR	P49841	GSK3B	S142	V137A	137	Missense	distal	-5	no	7.933	7.630	EPSD	ICGC;COSMIC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	O75952	CABYR	P49841	GSK3B	S339	E337D	337	Missense	proximal	-2	no	10.741	10.829	EPSD	ICGC;COSMIC	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	O75952	CABYR	P49841	GSK3B	S343	E337D	337	Missense	distal	-6	no	7.555	7.592	EPSD	ICGC;COSMIC	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	Q01518	CAP1	P49841	GSK3B	S34	R29L	29	Missense	distal	-5	no	9.154	8.566	EPSD	ICGC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	Q01518	CAP1	P49841	GSK3B	S308	T307S	307	Missense	proximal	-1	no	6.186	6.261	EPSD;PhosphoSitePlus	ICGC;COSMIC	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	Q01518	CAP1	P49841	GSK3B	S308	Q306K	306	Missense	proximal	-2	no	6.186	6.096	EPSD;PhosphoSitePlus	ICGC;COSMIC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	Q01518	CAP1	P49841	GSK3B	S310	T307S	307	Missense	distal	-3	no	7.057	7.032	PhosphoSitePlus;EPSD	ICGC;COSMIC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	Q01518	CAP1	P49841	GSK3B	S310	Q306K	306	Missense	distal	-4	no	7.057	7.022	PhosphoSitePlus;EPSD	ICGC;COSMIC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	P04150	NR3C1	P49841	GSK3B	T8	E13Q	13	Missense	distal	5	no	6.709	6.378	EPSD	ICGC;COSMIC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	P04150	NR3C1	P49841	GSK3B	T8	S3F	3	Missense	distal	-5	no	6.709	7.269	EPSD	ICGC	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	P04150	NR3C1	P49841	GSK3B	S45	A49D	49	Missense	distal	4	no	6.427	6.415	EPSD	ICGC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	P04150	NR3C1	P49841	GSK3B	S141	N138K	138	Missense	distal	-3	no	6.393	6.511	EPSD	ICGC	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	P04150	NR3C1	P49841	GSK3B	S226	E221K	221	Missense	distal	-5	no	6.132	5.901	EPSD	ICGC;COSMIC	6.007	Loss
CMGC_GSK_GSK3B_ST	P04150	NR3C1	P49841	GSK3B	S226	E231K	231	Missense	distal	5	no	6.132	5.264	EPSD	ICGC;COSMIC	6.007	Loss
CMGC_GSK_GSK3B_ST	P04150	NR3C1	P49841	GSK3B	S267	S269G	269	Missense	proximal	2	no	6.655	6.397	EPSD	ICGC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	P04150	NR3C1	P49841	GSK3B	S267	S269N	269	Missense	proximal	2	no	6.655	6.124	EPSD	ICGC;COSMIC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	P04150	NR3C1	P49841	GSK3B	S404	T411S	411	Missense	distal	7	no	11.548	11.607	PhosphoSitePlus	ICGC;COSMIC	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	P04150	NR3C1	P49841	GSK3B	S407	T411S	411	Missense	distal	4	no	6.996	7.865	EPSD	ICGC;COSMIC	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	P04150	NR3C1	P49841	GSK3B	S408	T411S	411	Missense	distal	3	no	6.121	6.154	EPSD	ICGC;COSMIC	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	P04150	NR3C1	P49841	GSK3B	S409	T411S	411	Missense	proximal	2	no	6.328	6.201	EPSD	ICGC;COSMIC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	Q9NP62	GCM1	P49841	GSK3B	S182	G185V	185	Missense	distal	3	no	6.817	6.565	EPSD	ICGC;COSMIC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	Q9NP62	GCM1	P49841	GSK3B	S182	A175E	175	Missense	distal	-7	no	6.817	6.827	EPSD	ICGC	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	Q9NP62	GCM1	P49841	GSK3B	S182	A175S	175	Missense	distal	-7	no	6.817	6.795	EPSD	ICGC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	Q00613	HSF1	P49841	GSK3B	S237	P239L	239	Missense	proximal	2	no	6.380	5.996	EPSD	ICGC;CCLE	6.007	Loss
CMGC_GSK_GSK3B_ST	Q00613	HSF1	P49841	GSK3B	S244	P239L	239	Missense	distal	-5	no	9.276	9.542	EPSD	ICGC;CCLE	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	Q00613	HSF1	P49841	GSK3B	S275	A278T	278	Missense	distal	3	no	10.301	10.605	EPSD	ICGC	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	Q00613	HSF1	P49841	GSK3B	S279	A278T	278	Missense	proximal	-1	no	9.764	9.844	EPSD	ICGC	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	Q00613	HSF1	P49841	GSK3B	S419	S421L	421	Missense	proximal	2	no	7.800	7.860	EPSD	ICGC;COSMIC	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	Q00613	HSF1	P49841	GSK3B	S419	S419G	419	Missense	central	0	yes	7.800	0.000	EPSD	ICGC;COSMIC	6.007	Loss
CMGC_GSK_GSK3B_ST	Q00613	HSF1	P49841	GSK3B	S444	A437S	437	Missense	distal	-7	no	8.709	8.687	EPSD	ICGC;COSMIC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	Q9HB09	BCL2L12	P49841	GSK3B	T117	A123S	123	Missense	distal	6	no	12.033	12.034	EPSD	ICGC	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	Q9HB09	BCL2L12	P49841	GSK3B	S121	A123S	123	Missense	proximal	2	no	8.641	8.633	EPSD	ICGC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	Q9HB09	BCL2L12	P49841	GSK3B	S156	R160H	160	Missense	distal	4	no	6.428	5.710	PhosphoSitePlus	ICGC	6.007	Loss
CMGC_GSK_GSK3B_ST	Q9HB09	BCL2L12	P49841	GSK3B	S156	P154L	154	Missense	proximal	-2	no	6.428	6.098	PhosphoSitePlus	ICGC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	Q9HB09	BCL2L12	P49841	GSK3B	T171	P169L	169	Missense	proximal	-2	no	7.344	7.014	EPSD	ICGC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	Q9HB09	BCL2L12	P49841	GSK3B	S243	A247S	247	Missense	distal	4	no	5.509	7.921	EPSD	ICGC;COSMIC	6.007	Gain
CMGC_GSK_GSK3B_ST	O75581	LRP6	P49841	GSK3B	T420	D421E	421	Missense	proximal	1	no	6.201	5.471	EPSD	ICGC	6.007	Loss
CMGC_GSK_GSK3B_ST	O75581	LRP6	P49841	GSK3B	T1001	S997R	997	Missense	distal	-4	no	8.027	6.840	EPSD	ICGC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	O75581	LRP6	P49841	GSK3B	T1001	S1005R	1005	Missense	distal	4	no	8.027	4.989	EPSD	ICGC	6.007	Loss
CMGC_GSK_GSK3B_ST	O75581	LRP6	P49841	GSK3B	T1001	T1001N	1001	Missense	central	0	yes	8.027	0.000	EPSD	ICGC	6.007	Loss
CMGC_GSK_GSK3B_ST	O75581	LRP6	P49841	GSK3B	T1001	V1004A	1004	Missense	distal	3	no	8.027	7.898	EPSD	ICGC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	Q9H0B6	KLC2	P49841	GSK3B	S151	P152T	152	Missense	proximal	1	no	6.767	3.576	EPSD	ICGC;COSMIC	6.007	Loss
CMGC_GSK_GSK3B_ST	Q9H0B6	KLC2	P49841	GSK3B	S175	G182R	182	Missense	distal	7	no	10.231	10.649	EPSD	ICGC;COSMIC	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	Q9H0B6	KLC2	P49841	GSK3B	S175	Q174L	174	Missense	proximal	-1	no	10.231	10.262	EPSD	ICGC;COSMIC	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	Q9H0B6	KLC2	P49841	GSK3B	S175	P178T	178	Missense	distal	3	no	10.231	10.180	EPSD	ICGC;COSMIC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	Q9H0B6	KLC2	P49841	GSK3B	S179	G182R	182	Missense	distal	3	no	7.675	7.260	EPSD	ICGC;COSMIC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	Q9H0B6	KLC2	P49841	GSK3B	S179	Q174L	174	Missense	distal	-5	no	7.675	7.641	EPSD	ICGC;COSMIC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	Q9H0B6	KLC2	P49841	GSK3B	S179	P178T	178	Missense	proximal	-1	no	7.675	7.543	EPSD	ICGC;COSMIC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	Q9H0B6	KLC2	P49841	GSK3B	S445	C441F	441	Missense	distal	-4	no	5.428	6.388	EPSD	ICGC;COSMIC	6.007	Gain
CMGC_GSK_GSK3B_ST	Q9H0B6	KLC2	P49841	GSK3B	T450	A457S	457	Missense	distal	7	no	6.253	5.905	EPSD	ICGC	6.007	Loss
CMGC_GSK_GSK3B_ST	Q9H0B6	KLC2	P49841	GSK3B	S521	P517S	517	Missense	distal	-4	no	5.641	6.205	EPSD	ICGC;COSMIC	6.007	Gain
CMGC_GSK_GSK3B_ST	Q9H0B6	KLC2	P49841	GSK3B	T568	Q570E	570	Missense	proximal	2	no	6.608	6.298	EPSD	ICGC;COSMIC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	Q9H0B6	KLC2	P49841	GSK3B	T568	T568N	568	Missense	central	0	yes	6.608	0.000	EPSD	ICGC;COSMIC	6.007	Loss
CMGC_GSK_GSK3B_ST	Q9H0B6	KLC2	P49841	GSK3B	S602	G597V	597	Missense	distal	-5	no	7.520	7.634	EPSD	ICGC	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	Q9H0B6	KLC2	P49841	GSK3B	S604	G597V	597	Missense	distal	-7	no	7.711	7.734	EPSD	ICGC	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	Q6U7Q0	ZNF322	P49841	GSK3B	T79	Q82K	82	Missense	distal	3	no	6.537	6.448	EPSD	ICGC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	Q6U7Q0	ZNF322	P49841	GSK3B	S391	E389K	389	Missense	proximal	-2	no	10.846	10.815	PhosphoSitePlus	ICGC;COSMIC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	Q6U7Q0	ZNF322	P49841	GSK3B	S391	H394N	394	Missense	distal	3	no	10.846	10.923	PhosphoSitePlus	ICGC;COSMIC	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	Q6U7Q0	ZNF322	P49841	GSK3B	S391	A395E	395	Missense	distal	4	no	10.846	11.237	PhosphoSitePlus	ICGC	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	Q6R327	RICTOR	P49841	GSK3B	T31	N37K	37	Missense	distal	6	no	6.382	6.383	EPSD	ICGC	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	Q6R327	RICTOR	P49841	GSK3B	S265	Q272K	272	Missense	distal	7	no	7.362	7.203	EPSD	ICGC;COSMIC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	Q6R327	RICTOR	P49841	GSK3B	S265	P266Q	266	Missense	proximal	1	no	7.362	4.094	EPSD	ICGC;COSMIC	6.007	Loss
CMGC_GSK_GSK3B_ST	Q6R327	RICTOR	P49841	GSK3B	S704	G711V	711	Missense	distal	7	no	5.908	6.314	EPSD	ICGC	6.007	Gain
CMGC_GSK_GSK3B_ST	Q6R327	RICTOR	P49841	GSK3B	S704	L700R	700	Missense	distal	-4	no	5.908	6.072	EPSD	ICGC;COSMIC	6.007	Gain
CMGC_GSK_GSK3B_ST	Q6R327	RICTOR	P49841	GSK3B	S1026	S1031C	1031	Missense	distal	5	no	6.716	5.477	EPSD	ICGC;COSMIC;GDSC;CCLE	6.007	Loss
CMGC_GSK_GSK3B_ST	Q6R327	RICTOR	P49841	GSK3B	S1031	S1031C	1031	Missense	central	0	yes	8.808	0.000	EPSD	ICGC;COSMIC;GDSC;CCLE	6.007	Loss
CMGC_GSK_GSK3B_ST	Q6R327	RICTOR	P49841	GSK3B	S1122	P1115S	1115	Missense	distal	-7	no	6.052	6.054	EPSD	ICGC	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	Q6R327	RICTOR	P49841	GSK3B	S1144	T1148K	1148	Missense	distal	4	no	6.854	4.520	EPSD	ICGC	6.007	Loss
CMGC_GSK_GSK3B_ST	Q6R327	RICTOR	P49841	GSK3B	S1144	H1143Y	1143	Missense	proximal	-1	no	6.854	6.765	EPSD	ICGC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	Q6R327	RICTOR	P49841	GSK3B	T1148	T1148K	1148	Missense	central	0	yes	7.539	0.000	EPSD	ICGC	6.007	Loss
CMGC_GSK_GSK3B_ST	Q6R327	RICTOR	P49841	GSK3B	T1148	H1143Y	1143	Missense	distal	-5	no	7.539	8.025	EPSD	ICGC	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	Q6R327	RICTOR	P49841	GSK3B	T1152	T1148K	1148	Missense	distal	-4	no	7.207	6.678	EPSD	ICGC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	Q6R327	RICTOR	P49841	GSK3B	S1227	M1232V	1232	Missense	distal	5	no	9.055	8.693	EPSD	ICGC;COSMIC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	Q6R327	RICTOR	P49841	GSK3B	S1227	S1230T	1230	Missense	distal	3	no	9.055	9.022	EPSD	ICGC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	Q6R327	RICTOR	P49841	GSK3B	S1231	M1232V	1232	Missense	proximal	1	no	9.116	9.712	EPSD	ICGC;COSMIC	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	Q6R327	RICTOR	P49841	GSK3B	S1231	S1230T	1230	Missense	proximal	-1	no	9.116	9.041	EPSD	ICGC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	Q6R327	RICTOR	P49841	GSK3B	S1235	M1232V	1232	Missense	distal	-3	no	9.254	9.449	EPSD;PhosphoSitePlus	ICGC;COSMIC	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	Q6R327	RICTOR	P49841	GSK3B	S1235	S1230T	1230	Missense	distal	-5	no	9.254	9.543	EPSD;PhosphoSitePlus	ICGC	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	Q6R327	RICTOR	P49841	GSK3B	T1271	H1276R	1276	Missense	distal	5	no	5.786	6.776	EPSD	ICGC;COSMIC	6.007	Gain
CMGC_GSK_GSK3B_ST	Q6R327	RICTOR	P49841	GSK3B	S1278	H1276R	1276	Missense	proximal	-2	no	6.547	6.537	EPSD	ICGC;COSMIC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	Q6R327	RICTOR	P49841	GSK3B	S1278	Q1273K	1273	Missense	distal	-5	no	6.547	6.604	EPSD	ICGC;COSMIC	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	Q6R327	RICTOR	P49841	GSK3B	S1284	P1290A	1290	Missense	distal	6	no	6.416	6.412	EPSD	ICGC;COSMIC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	Q6R327	RICTOR	P49841	GSK3B	S1320	R1325T	1325	Missense	distal	5	no	8.162	7.823	EPSD	ICGC;COSMIC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	Q6R327	RICTOR	P49841	GSK3B	S1320	R1325K	1325	Missense	distal	5	no	8.162	7.288	EPSD	ICGC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	Q6R327	RICTOR	P49841	GSK3B	S1353	S1348C	1348	Missense	distal	-5	no	5.531	6.050	EPSD	ICGC;COSMIC	6.007	Gain
CMGC_GSK_GSK3B_ST	Q6R327	RICTOR	P49841	GSK3B	T1376	T1376A	1376	Missense	central	0	yes	6.930	0.000	EPSD	ICGC;COSMIC	6.007	Loss
CMGC_GSK_GSK3B_ST	Q6R327	RICTOR	P49841	GSK3B	T1376	S1373F	1373	Missense	distal	-3	no	6.930	6.997	EPSD	ICGC;COSMIC	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	Q6R327	RICTOR	P49841	GSK3B	S1581	S1588N	1588	Missense	distal	7	no	7.230	7.353	EPSD	ICGC	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	Q6R327	RICTOR	P49841	GSK3B	S1581	S1581Y	1581	Missense	central	0	yes	7.230	0.000	EPSD	ICGC;COSMIC	6.007	Loss
CMGC_GSK_GSK3B_ST	Q6R327	RICTOR	P49841	GSK3B	S1585	S1588N	1588	Missense	distal	3	no	6.811	6.859	EPSD	ICGC	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	Q6R327	RICTOR	P49841	GSK3B	S1585	S1581Y	1581	Missense	distal	-4	no	6.811	6.010	EPSD	ICGC;COSMIC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	Q6R327	RICTOR	P49841	GSK3B	S1587	S1588N	1588	Missense	proximal	1	no	6.424	4.749	EPSD	ICGC	6.007	Loss
CMGC_GSK_GSK3B_ST	Q6R327	RICTOR	P49841	GSK3B	S1587	S1581Y	1581	Missense	distal	-6	no	6.424	6.338	EPSD	ICGC;COSMIC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	Q6R327	RICTOR	P49841	GSK3B	S1588	S1588N	1588	Missense	central	0	yes	7.334	0.000	EPSD	ICGC	6.007	Loss
CMGC_GSK_GSK3B_ST	Q6R327	RICTOR	P49841	GSK3B	S1588	S1581Y	1581	Missense	distal	-7	no	7.334	7.362	EPSD	ICGC;COSMIC	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	P01106	MYC	P49841	GSK3B	S67	P72S	72	Missense	distal	5	no	7.689	6.735	EPSD	ICGC;COSMIC;GDSC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	P01106	MYC	P49841	GSK3B	S67	P72A	72	Missense	distal	5	no	7.689	6.660	EPSD	ICGC;COSMIC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	P01106	MYC	P49841	GSK3B	S67	P72L	72	Missense	distal	5	no	7.689	6.408	EPSD	ICGC;COSMIC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	P01106	MYC	P49841	GSK3B	S67	P72T	72	Missense	distal	5	no	7.689	6.712	EPSD	ICGC;COSMIC;GDSC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	P01106	MYC	P49841	GSK3B	S71	P72S	72	Missense	proximal	1	no	8.090	4.245	EPSD	ICGC;COSMIC;GDSC	6.007	Loss
CMGC_GSK_GSK3B_ST	P01106	MYC	P49841	GSK3B	S71	P72A	72	Missense	proximal	1	no	8.090	4.357	EPSD	ICGC;COSMIC	6.007	Loss
CMGC_GSK_GSK3B_ST	P01106	MYC	P49841	GSK3B	S71	P72L	72	Missense	proximal	1	no	8.090	5.229	EPSD	ICGC;COSMIC	6.007	Loss
CMGC_GSK_GSK3B_ST	P01106	MYC	P49841	GSK3B	S71	P72T	72	Missense	proximal	1	no	8.090	4.899	EPSD	ICGC;COSMIC;GDSC	6.007	Loss
CMGC_GSK_GSK3B_ST	P35612	ADD2	P49841	GSK3B	S11	T5M	5	Missense	distal	-6	no	7.707	7.712	EPSD	ICGC;COSMIC;CCLE	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	P35612	ADD2	P49841	GSK3B	S11	P13L	13	Missense	proximal	2	no	7.707	7.323	EPSD	ICGC;COSMIC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	P35612	ADD2	P49841	GSK3B	S11	A10D	10	Missense	proximal	-1	no	7.707	7.802	EPSD	ICGC;COSMIC	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	P35612	ADD2	P49841	GSK3B	S11	A9V	9	Missense	proximal	-2	no	7.707	8.009	EPSD	ICGC;GDSC	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	P35612	ADD2	P49841	GSK3B	S11	G17W	17	Missense	distal	6	no	7.707	7.695	EPSD	ICGC;COSMIC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	P35612	ADD2	P49841	GSK3B	S60	E65Q	65	Missense	distal	5	no	6.927	6.596	EPSD	ICGC;COSMIC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	P35612	ADD2	P49841	GSK3B	S60	M56V	56	Missense	distal	-4	no	6.927	6.753	EPSD	ICGC;COSMIC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	P35612	ADD2	P49841	GSK3B	S60	L58Q	58	Missense	proximal	-2	no	6.927	6.956	EPSD	ICGC;COSMIC	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	P35612	ADD2	P49841	GSK3B	T392	H394P	394	Missense	proximal	2	no	5.381	6.150	EPSD	ICGC;COSMIC	6.007	Gain
CMGC_GSK_GSK3B_ST	P35612	ADD2	P49841	GSK3B	S455	T461M	461	Missense	distal	6	no	6.726	6.719	EPSD	ICGC;COSMIC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	P35612	ADD2	P49841	GSK3B	S455	P458H	458	Missense	distal	3	no	6.726	6.680	EPSD	ICGC;COSMIC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	P35612	ADD2	P49841	GSK3B	S455	S452R	452	Missense	distal	-3	no	6.726	6.895	EPSD	ICGC	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	P35612	ADD2	P49841	GSK3B	S455	T460N	460	Missense	distal	5	no	6.726	6.428	EPSD	ICGC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	P35612	ADD2	P49841	GSK3B	S528	S522R	522	Missense	distal	-6	no	7.100	7.042	EPSD	ICGC;COSMIC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	P35612	ADD2	P49841	GSK3B	S528	R529Q	529	Missense	proximal	1	no	7.100	6.151	EPSD	ICGC;COSMIC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	P35612	ADD2	P49841	GSK3B	S535	G541R	541	Missense	distal	6	no	6.054	6.053	EPSD	ICGC;COSMIC;GDSC;CCLE	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	P35612	ADD2	P49841	GSK3B	S535	R529Q	529	Missense	distal	-6	no	6.054	6.107	EPSD	ICGC;COSMIC	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	P35612	ADD2	P49841	GSK3B	S535	G541E	541	Missense	distal	6	no	6.054	6.052	EPSD	ICGC;COSMIC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	P35612	ADD2	P49841	GSK3B	T545	T552M	552	Missense	distal	7	no	5.820	6.248	EPSD	ICGC;COSMIC	6.007	Gain
CMGC_GSK_GSK3B_ST	P35612	ADD2	P49841	GSK3B	S549	P556H	556	Missense	distal	7	no	5.480	6.169	EPSD	ICGC;COSMIC	6.007	Gain
CMGC_GSK_GSK3B_ST	P35612	ADD2	P49841	GSK3B	S592	P587S	587	Missense	distal	-5	no	10.486	10.642	EPSD	ICGC;COSMIC	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	P35612	ADD2	P49841	GSK3B	S592	P593H	593	Missense	proximal	1	no	10.486	6.785	EPSD	ICGC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	P35612	ADD2	P49841	GSK3B	S596	P593H	593	Missense	distal	-3	no	7.516	7.745	EPSD	ICGC	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	P35612	ADD2	P49841	GSK3B	S600	P593H	593	Missense	distal	-7	no	12.031	12.051	EPSD	ICGC	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	P35612	ADD2	P49841	GSK3B	S604	A609S	609	Missense	distal	5	no	7.723	7.798	EPSD	ICGC;COSMIC	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	P35612	ADD2	P49841	GSK3B	S613	A609S	609	Missense	distal	-4	no	10.662	11.822	PhosphoSitePlus;EPSD	ICGC;COSMIC	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	P35612	ADD2	P49841	GSK3B	S613	P614R	614	Missense	proximal	1	no	10.662	8.342	PhosphoSitePlus;EPSD	ICGC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	P35612	ADD2	P49841	GSK3B	S613	K612E	612	Missense	proximal	-1	no	10.662	10.595	PhosphoSitePlus;EPSD	ICGC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	P35612	ADD2	P49841	GSK3B	S617	P614R	614	Missense	distal	-3	no	9.420	9.706	EPSD	ICGC	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	P35612	ADD2	P49841	GSK3B	S617	K612E	612	Missense	distal	-5	no	9.420	9.651	EPSD	ICGC	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	P35612	ADD2	P49841	GSK3B	S617	S621C	621	Missense	distal	4	no	9.420	3.288	EPSD	ICGC	6.007	Loss
CMGC_GSK_GSK3B_ST	P35612	ADD2	P49841	GSK3B	S667	M669I	669	Missense	proximal	2	no	6.656	7.288	EPSD	ICGC	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	P35612	ADD2	P49841	GSK3B	S667	S663R	663	Missense	distal	-4	no	6.656	5.469	EPSD	ICGC	6.007	Loss
CMGC_GSK_GSK3B_ST	P35612	ADD2	P49841	GSK3B	S667	D674E	674	Missense	distal	7	no	6.656	6.640	EPSD	ICGC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	P35612	ADD2	P49841	GSK3B	T671	M669I	669	Missense	proximal	-2	no	6.090	6.411	EPSD	ICGC	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	P35612	ADD2	P49841	GSK3B	T671	D674E	674	Missense	distal	3	no	6.090	5.976	EPSD	ICGC	6.007	Loss
CMGC_GSK_GSK3B_ST	P35612	ADD2	P49841	GSK3B	S689	G690D	690	Missense	proximal	1	no	8.096	8.187	EPSD	ICGC	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	P35612	ADD2	P49841	GSK3B	S693	P698H	698	Missense	distal	5	no	12.171	10.544	EPSD;PhosphoSitePlus	ICGC;COSMIC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	P35612	ADD2	P49841	GSK3B	S693	G690D	690	Missense	distal	-3	no	12.171	12.221	EPSD;PhosphoSitePlus	ICGC	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	P35612	ADD2	P49841	GSK3B	S697	P698H	698	Missense	proximal	1	no	10.178	6.478	EPSD	ICGC;COSMIC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	P35612	ADD2	P49841	GSK3B	S697	G690D	690	Missense	distal	-7	no	10.178	10.183	EPSD	ICGC	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	Q15691	MAPRE1	P49841	GSK3B	S165	A170T	170	Missense	distal	5	no	6.685	6.737	EPSD	ICGC;COSMIC;GDSC;CCLE	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	P25054	APC	P49841	GSK3B	T35	N30K	30	Missense	distal	-5	no	5.620	6.112	EPSD	ICGC	6.007	Gain
CMGC_GSK_GSK3B_ST	P25054	APC	P49841	GSK3B	S127	T131A	131	Missense	distal	4	no	6.184	4.641	EPSD	ICGC;COSMIC	6.007	Loss
CMGC_GSK_GSK3B_ST	P25054	APC	P49841	GSK3B	S127	V124A	124	Missense	distal	-3	no	6.184	6.037	EPSD	ICGC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	P25054	APC	P49841	GSK3B	S127	G122W	122	Missense	distal	-5	no	6.184	6.159	EPSD	ICGC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	P25054	APC	P49841	GSK3B	S293	S294Y	294	Missense	proximal	1	no	5.674	6.200	EPSD	ICGC;COSMIC	6.007	Gain
CMGC_GSK_GSK3B_ST	P25054	APC	P49841	GSK3B	S331	D326Y	326	Missense	distal	-5	no	5.665	6.045	EPSD	ICGC	6.007	Gain
CMGC_GSK_GSK3B_ST	P25054	APC	P49841	GSK3B	S744	S748I	748	Missense	distal	4	no	10.614	7.293	EPSD	ICGC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	P25054	APC	P49841	GSK3B	S744	P750S	750	Missense	distal	6	no	10.614	10.612	EPSD	ICGC;COSMIC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	P25054	APC	P49841	GSK3B	S747	S748I	748	Missense	proximal	1	no	6.209	6.173	EPSD	ICGC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	P25054	APC	P49841	GSK3B	S747	P750S	750	Missense	distal	3	no	6.209	6.192	EPSD	ICGC;COSMIC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	P25054	APC	P49841	GSK3B	S780	R786C	786	Missense	distal	6	no	7.539	7.531	EPSD	ICGC;COSMIC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	P25054	APC	P49841	GSK3B	T899	S900Y	900	Missense	proximal	1	no	6.638	7.164	EPSD	ICGC;COSMIC	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	P25054	APC	P49841	GSK3B	S906	S900Y	900	Missense	distal	-6	no	6.850	6.763	EPSD	ICGC;COSMIC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	P25054	APC	P49841	GSK3B	S906	T910N	910	Missense	distal	4	no	6.850	4.108	EPSD	ICGC;COSMIC	6.007	Loss
CMGC_GSK_GSK3B_ST	P25054	APC	P49841	GSK3B	S906	S908Y	908	Missense	proximal	2	no	6.850	6.617	EPSD	ICGC;COSMIC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	P25054	APC	P49841	GSK3B	S966	S969I	969	Missense	distal	3	no	8.445	8.025	EPSD	ICGC;COSMIC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	P25054	APC	P49841	GSK3B	S966	S959P	959	Missense	distal	-7	no	8.445	8.444	EPSD	ICGC;COSMIC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	P25054	APC	P49841	GSK3B	S1028	S1028R	1028	Missense	central	0	yes	7.279	0.000	EPSD	ICGC;COSMIC	6.007	Loss
CMGC_GSK_GSK3B_ST	P25054	APC	P49841	GSK3B	S1038	R1040S	1040	Missense	proximal	2	no	7.492	7.473	EPSD	ICGC;COSMIC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	P25054	APC	P49841	GSK3B	S1038	R1040T	1040	Missense	proximal	2	no	7.492	7.600	EPSD	ICGC;COSMIC	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	P25054	APC	P49841	GSK3B	S1038	P1043S	1043	Missense	distal	5	no	7.492	6.538	EPSD	ICGC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	P25054	APC	P49841	GSK3B	S1038	Q1041E	1041	Missense	distal	3	no	7.492	7.510	EPSD	ICGC;COSMIC	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	P25054	APC	P49841	GSK3B	S1100	A1107V	1107	Missense	distal	7	no	9.022	9.100	EPSD	ICGC;COSMIC	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	P25054	APC	P49841	GSK3B	S1100	R1105W	1105	Missense	distal	5	no	9.022	7.721	EPSD	ICGC;COSMIC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	P25054	APC	P49841	GSK3B	T1218	T1218A	1218	Missense	central	0	yes	6.412	0.000	EPSD	ICGC;GDSC;CCLE	6.007	Loss
CMGC_GSK_GSK3B_ST	P25054	APC	P49841	GSK3B	S1219	T1218A	1218	Missense	proximal	-1	no	6.651	6.571	EPSD	ICGC;GDSC;CCLE	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	P25054	APC	P49841	GSK3B	S1272	E1265D	1265	Missense	distal	-7	no	6.638	6.608	EPSD	ICGC;COSMIC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	P25054	APC	P49841	GSK3B	S1272	R1273I	1273	Missense	proximal	1	no	6.638	5.076	EPSD	ICGC	6.007	Loss
CMGC_GSK_GSK3B_ST	P25054	APC	P49841	GSK3B	S1278	R1273I	1273	Missense	distal	-5	no	6.066	5.841	EPSD	ICGC	6.007	Loss
CMGC_GSK_GSK3B_ST	P25054	APC	P49841	GSK3B	S1360	A1366V	1366	Missense	distal	6	no	10.460	10.452	EPSD	ICGC;COSMIC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	P25054	APC	P49841	GSK3B	S1364	A1366V	1366	Missense	proximal	2	no	7.800	7.523	EPSD	ICGC;COSMIC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	P25054	APC	P49841	GSK3B	T1368	A1366V	1366	Missense	proximal	-2	no	7.906	8.208	EPSD	ICGC;COSMIC	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	P25054	APC	P49841	GSK3B	S1371	A1366V	1366	Missense	distal	-5	no	6.484	6.786	EPSD	ICGC;COSMIC	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	P25054	APC	P49841	GSK3B	T1380	P1381T	1381	Missense	proximal	1	no	6.505	3.314	EPSD	ICGC;COSMIC	6.007	Loss
CMGC_GSK_GSK3B_ST	P25054	APC	P49841	GSK3B	T1380	R1386I	1386	Missense	distal	6	no	6.505	6.509	EPSD	ICGC	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	P25054	APC	P49841	GSK3B	S1385	P1381T	1381	Missense	distal	-4	no	6.310	6.538	EPSD	ICGC;COSMIC	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	P25054	APC	P49841	GSK3B	S1385	R1386I	1386	Missense	proximal	1	no	6.310	4.749	EPSD	ICGC	6.007	Loss
CMGC_GSK_GSK3B_ST	P25054	APC	P49841	GSK3B	S1385	T1388A	1388	Missense	distal	3	no	6.310	6.006	EPSD	ICGC;COSMIC	6.007	Loss
CMGC_GSK_GSK3B_ST	P25054	APC	P49841	GSK3B	S1395	R1399S	1399	Missense	distal	4	no	4.887	7.925	EPSD	ICGC;COSMIC	6.007	Gain
CMGC_GSK_GSK3B_ST	P25054	APC	P49841	GSK3B	S1398	A1402T	1402	Missense	distal	4	no	5.949	7.491	EPSD	ICGC;COSMIC	6.007	Gain
CMGC_GSK_GSK3B_ST	P25054	APC	P49841	GSK3B	S1426	S1419N	1419	Missense	distal	-7	no	7.675	7.681	EPSD	ICGC;COSMIC	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	P25054	APC	P49841	GSK3B	S1426	Q1429R	1429	Missense	distal	3	no	7.675	7.342	EPSD	ICGC;COSMIC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	P25054	APC	P49841	GSK3B	S1426	M1431T	1431	Missense	distal	5	no	7.675	7.792	EPSD	ICGC	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	P25054	APC	P49841	GSK3B	T1438	R1435K	1435	Missense	distal	-3	no	8.114	7.969	EPSD	ICGC;COSMIC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	P25054	APC	P49841	GSK3B	T1438	M1431T	1431	Missense	distal	-7	no	8.114	8.120	EPSD	ICGC	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	P25054	APC	P49841	GSK3B	T1633	G1635R	1635	Missense	proximal	2	no	6.346	6.623	EPSD	ICGC;COSMIC	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	P25054	APC	P49841	GSK3B	T1633	G1635W	1635	Missense	proximal	2	no	6.346	6.193	EPSD	ICGC;COSMIC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	P25054	APC	P49841	GSK3B	S1652	T1647A	1647	Missense	distal	-5	no	6.674	6.662	EPSD	ICGC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	P25054	APC	P49841	GSK3B	T1661	P1665S	1665	Missense	distal	4	no	3.347	6.318	EPSD	ICGC;COSMIC	6.007	Gain
CMGC_GSK_GSK3B_ST	P25054	APC	P49841	GSK3B	S1664	P1665S	1665	Missense	proximal	1	no	8.205	4.360	EPSD	ICGC;COSMIC	6.007	Loss
CMGC_GSK_GSK3B_ST	P25054	APC	P49841	GSK3B	S1754	S1756F	1756	Missense	proximal	2	no	6.118	5.773	EPSD	ICGC	6.007	Loss
CMGC_GSK_GSK3B_ST	P25054	APC	P49841	GSK3B	T1847	F1840V	1840	Missense	distal	-7	no	6.378	6.389	EPSD	ICGC;COSMIC	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	P25054	APC	P49841	GSK3B	T1852	R1858L	1858	Missense	distal	6	no	6.569	6.568	EPSD	ICGC;COSMIC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	P25054	APC	P49841	GSK3B	S1857	R1858L	1858	Missense	proximal	1	no	8.480	7.939	EPSD	ICGC;COSMIC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	P25054	APC	P49841	GSK3B	S2054	K2052N	2052	Missense	proximal	-2	no	6.313	6.219	EPSD	ICGC;COSMIC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	P25054	APC	P49841	GSK3B	S2110	I2111T	2111	Missense	proximal	1	no	5.433	6.123	EPSD	ICGC;COSMIC	6.007	Gain
CMGC_GSK_GSK3B_ST	P25054	APC	P49841	GSK3B	S2174	P2170T	2170	Missense	distal	-4	no	6.229	6.457	EPSD	ICGC;COSMIC	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	P25054	APC	P49841	GSK3B	S2240	G2235V	2235	Missense	distal	-5	no	6.762	6.876	EPSD	ICGC;COSMIC	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	P25054	APC	P49841	GSK3B	S2283	V2278L	2278	Missense	distal	-5	no	6.401	5.930	EPSD	ICGC	6.007	Loss
CMGC_GSK_GSK3B_ST	P25054	APC	P49841	GSK3B	S2300	R2305T	2305	Missense	distal	5	no	9.383	9.044	EPSD	ICGC;COSMIC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	P25054	APC	P49841	GSK3B	S2304	R2305T	2305	Missense	proximal	1	no	10.068	9.197	EPSD	ICGC;COSMIC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	P25054	APC	P49841	GSK3B	S2304	R2311I	2311	Missense	distal	7	no	10.068	9.966	EPSD	ICGC;COSMIC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	P25054	APC	P49841	GSK3B	S2307	R2305T	2305	Missense	proximal	-2	no	7.358	7.500	EPSD	ICGC;COSMIC	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	P25054	APC	P49841	GSK3B	S2307	R2311I	2311	Missense	distal	4	no	7.358	7.074	EPSD	ICGC;COSMIC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	P25054	APC	P49841	GSK3B	T2308	R2305T	2305	Missense	distal	-3	no	6.717	6.573	EPSD	ICGC;COSMIC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	P25054	APC	P49841	GSK3B	T2308	R2311I	2311	Missense	distal	3	no	6.717	6.668	EPSD	ICGC;COSMIC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	P25054	APC	P49841	GSK3B	S2328	G2332S	2332	Missense	distal	4	no	2.775	6.018	EPSD	ICGC	6.007	Gain
CMGC_GSK_GSK3B_ST	P25054	APC	P49841	GSK3B	S2337	R2333T	2333	Missense	distal	-4	no	7.677	8.528	EPSD	ICGC;COSMIC	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	P25054	APC	P49841	GSK3B	S2337	P2338H	2338	Missense	proximal	1	no	7.677	3.977	EPSD	ICGC	6.007	Loss
CMGC_GSK_GSK3B_ST	P25054	APC	P49841	GSK3B	S2337	G2332S	2332	Missense	distal	-5	no	7.677	7.211	EPSD	ICGC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	P25054	APC	P49841	GSK3B	S2337	S2330F	2330	Missense	distal	-7	no	7.677	7.687	EPSD	ICGC	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	P25054	APC	P49841	GSK3B	T2348	S2350F	2350	Missense	proximal	2	no	6.595	6.250	EPSD	ICGC;COSMIC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	P25054	APC	P49841	GSK3B	S2350	S2350F	2350	Missense	central	0	yes	7.290	0.000	EPSD	ICGC;COSMIC	6.007	Loss
CMGC_GSK_GSK3B_ST	P25054	APC	P49841	GSK3B	S2350	K2357T	2357	Missense	distal	7	no	7.290	7.300	EPSD	ICGC;COSMIC	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	P25054	APC	P49841	GSK3B	S2425	S2432L	2432	Missense	distal	7	no	7.244	7.230	EPSD	ICGC;COSMIC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	P25054	APC	P49841	GSK3B	S2425	R2431K	2431	Missense	distal	6	no	7.244	7.243	EPSD	ICGC;COSMIC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	P25054	APC	P49841	GSK3B	S2429	S2432L	2432	Missense	distal	3	no	6.304	6.003	EPSD	ICGC;COSMIC	6.007	Loss
CMGC_GSK_GSK3B_ST	P25054	APC	P49841	GSK3B	S2429	R2431K	2431	Missense	proximal	2	no	6.304	6.238	EPSD	ICGC;COSMIC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	P25054	APC	P49841	GSK3B	S2464	S2464C	2464	Missense	central	0	yes	6.799	0.000	EPSD	ICGC;COSMIC	6.007	Loss
CMGC_GSK_GSK3B_ST	P25054	APC	P49841	GSK3B	S2464	R2470I	2470	Missense	distal	6	no	6.799	6.803	EPSD	ICGC	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	P25054	APC	P49841	GSK3B	S2464	S2469F	2469	Missense	distal	5	no	6.799	6.132	EPSD	ICGC;COSMIC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	P25054	APC	P49841	GSK3B	S2464	S2459F	2459	Missense	distal	-5	no	6.799	7.359	EPSD	ICGC	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	P25054	APC	P49841	GSK3B	S2466	S2464C	2464	Missense	proximal	-2	no	7.295	6.983	EPSD	ICGC;COSMIC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	P25054	APC	P49841	GSK3B	S2466	R2470I	2470	Missense	distal	4	no	7.295	7.011	EPSD	ICGC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	P25054	APC	P49841	GSK3B	S2466	S2469F	2469	Missense	distal	3	no	7.295	7.084	EPSD	ICGC;COSMIC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	P25054	APC	P49841	GSK3B	S2466	S2459F	2459	Missense	distal	-7	no	7.295	7.305	EPSD	ICGC	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	P25054	APC	P49841	GSK3B	S2469	S2464C	2464	Missense	distal	-5	no	7.641	8.161	EPSD	ICGC;COSMIC	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	P25054	APC	P49841	GSK3B	S2469	R2470I	2470	Missense	proximal	1	no	7.641	6.080	EPSD	ICGC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	P25054	APC	P49841	GSK3B	S2469	S2469F	2469	Missense	central	0	yes	7.641	0.000	EPSD	ICGC;COSMIC	6.007	Loss
CMGC_GSK_GSK3B_ST	P25054	APC	P49841	GSK3B	S2473	R2470I	2470	Missense	distal	-3	no	10.333	10.278	EPSD	ICGC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	P25054	APC	P49841	GSK3B	S2473	S2469F	2469	Missense	distal	-4	no	10.333	9.179	EPSD	ICGC;COSMIC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	P25054	APC	P49841	GSK3B	S2512	D2519V	2519	Missense	distal	7	no	6.003	6.374	EPSD	ICGC;COSMIC	6.007	Gain
CMGC_GSK_GSK3B_ST	P25054	APC	P49841	GSK3B	S2531	R2525H	2525	Missense	distal	-6	no	6.477	6.500	EPSD	ICGC	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	P25054	APC	P49841	GSK3B	T2563	R2566K	2566	Missense	distal	3	no	7.337	7.582	EPSD	ICGC	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	P25054	APC	P49841	GSK3B	S2621	S2621C	2621	Missense	central	0	yes	9.358	0.000	EPSD	ICGC;COSMIC;GDSC	6.007	Loss
CMGC_GSK_GSK3B_ST	P25054	APC	P49841	GSK3B	S2621	S2625C	2625	Missense	distal	4	no	9.358	3.225	EPSD	ICGC	6.007	Loss
CMGC_GSK_GSK3B_ST	P25054	APC	P49841	GSK3B	S2625	V2630I	2630	Missense	distal	5	no	6.567	6.402	EPSD	ICGC;COSMIC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	P25054	APC	P49841	GSK3B	S2625	S2621C	2621	Missense	distal	-4	no	6.567	4.453	EPSD	ICGC;COSMIC;GDSC	6.007	Loss
CMGC_GSK_GSK3B_ST	P25054	APC	P49841	GSK3B	S2625	S2625C	2625	Missense	central	0	yes	6.567	0.000	EPSD	ICGC	6.007	Loss
CMGC_GSK_GSK3B_ST	P25054	APC	P49841	GSK3B	S2627	V2630I	2630	Missense	distal	3	no	7.373	7.161	EPSD	ICGC;COSMIC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	P25054	APC	P49841	GSK3B	S2627	S2621C	2621	Missense	distal	-6	no	7.373	7.362	EPSD	ICGC;COSMIC;GDSC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	P25054	APC	P49841	GSK3B	S2627	S2625C	2625	Missense	proximal	-2	no	7.373	7.062	EPSD	ICGC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	P25054	APC	P49841	GSK3B	S2627	G2633C	2633	Missense	distal	6	no	7.373	7.363	EPSD	ICGC;COSMIC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	P25054	APC	P49841	GSK3B	T2679	V2682L	2682	Missense	distal	3	no	6.363	6.271	EPSD	ICGC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	P25054	APC	P49841	GSK3B	T2679	G2672E	2672	Missense	distal	-7	no	6.363	6.398	EPSD	ICGC	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	P25054	APC	P49841	GSK3B	S2789	R2791W	2791	Missense	proximal	2	no	8.105	7.675	EPSD	ICGC;COSMIC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	P25054	APC	P49841	GSK3B	S2789	S2793I	2793	Missense	distal	4	no	8.105	4.783	EPSD	ICGC	6.007	Loss
CMGC_GSK_GSK3B_ST	P25054	APC	P49841	GSK3B	S2789	S2794I	2794	Missense	distal	5	no	8.105	7.439	EPSD	ICGC;COSMIC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	P25054	APC	P49841	GSK3B	S2799	S2793I	2793	Missense	distal	-6	no	6.612	6.549	EPSD	ICGC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	P25054	APC	P49841	GSK3B	S2799	S2794I	2794	Missense	distal	-5	no	6.612	7.084	EPSD	ICGC;COSMIC	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	P25054	APC	P49841	GSK3B	S2803	P2808A	2808	Missense	distal	5	no	6.932	5.903	EPSD	ICGC;COSMIC	6.007	Loss
CMGC_GSK_GSK3B_ST	P25054	APC	P49841	GSK3B	S2830	S2837A	2837	Missense	distal	7	no	6.059	6.407	EPSD	ICGC	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	P25054	APC	P49841	GSK3B	S2830	G2836W	2836	Missense	distal	6	no	6.059	6.047	EPSD	ICGC;COSMIC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	P25054	APC	P49841	GSK3B	S2837	S2837A	2837	Missense	central	0	yes	6.032	0.000	EPSD	ICGC	6.007	Loss
CMGC_GSK_GSK3B_ST	P25054	APC	P49841	GSK3B	S2837	G2836W	2836	Missense	proximal	-1	no	6.032	6.000	EPSD	ICGC;COSMIC	6.007	Loss
CMGC_GSK_GSK3B_ST	P25054	APC	P49841	GSK3B	S2837	L2839I	2839	Missense	proximal	2	no	6.032	6.033	EPSD	ICGC;COSMIC	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	Q99626	CDX2	P49841	GSK3B	S12	V18L	18	Missense	distal	6	no	6.474	6.480	EPSD	ICGC;COSMIC	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	Q99626	CDX2	P49841	GSK3B	S17	V18L	18	Missense	proximal	1	no	6.253	6.383	EPSD	ICGC;COSMIC	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	Q99626	CDX2	P49841	GSK3B	S60	P66L	66	Missense	distal	6	no	9.247	9.240	EPSD	ICGC;COSMIC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	Q99626	CDX2	P49841	GSK3B	S283	P284L	284	Missense	proximal	1	no	10.073	7.213	PhosphoSitePlus	ICGC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	Q99626	CDX2	P49841	GSK3B	S283	P284T	284	Missense	proximal	1	no	10.073	6.882	PhosphoSitePlus	ICGC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	Q99626	CDX2	P49841	GSK3B	S287	P293S	293	Missense	distal	6	no	7.105	7.103	EPSD	ICGC;COSMIC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	Q99626	CDX2	P49841	GSK3B	S287	P284L	284	Missense	distal	-3	no	7.105	7.231	EPSD	ICGC	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	Q99626	CDX2	P49841	GSK3B	S287	P284T	284	Missense	distal	-3	no	7.105	7.246	EPSD	ICGC	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	Q99626	CDX2	P49841	GSK3B	S291	P293S	293	Missense	proximal	2	no	7.019	6.575	EPSD	ICGC;COSMIC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	Q99626	CDX2	P49841	GSK3B	S291	P284L	284	Missense	distal	-7	no	7.019	7.020	EPSD	ICGC	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	Q99626	CDX2	P49841	GSK3B	S291	P284T	284	Missense	distal	-7	no	7.019	7.047	EPSD	ICGC	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	Q99626	CDX2	P49841	GSK3B	S295	P293S	293	Missense	proximal	-2	no	7.049	6.792	EPSD	ICGC;COSMIC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	P17812	CTPS1	P49841	GSK3B	S21	G15C	15	Missense	distal	-6	no	6.157	6.130	EPSD	ICGC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	P17812	CTPS1	P49841	GSK3B	S562	D565N	565	Missense	distal	3	no	7.706	7.659	EPSD	ICGC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	P17812	CTPS1	P49841	GSK3B	S571	D565N	565	Missense	distal	-6	no	8.812	8.835	PhosphoSitePlus	ICGC	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	P30291	WEE1	P49841	GSK3B	S45	E40G	40	Missense	distal	-5	no	6.052	6.087	EPSD	ICGC;COSMIC	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	P30291	WEE1	P49841	GSK3B	S123	A130V	130	Missense	distal	7	no	11.485	11.563	EPSD	ICGC;COSMIC	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	P30291	WEE1	P49841	GSK3B	S127	A130V	130	Missense	distal	3	no	6.438	6.567	EPSD	ICGC;COSMIC	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	P30291	WEE1	P49841	GSK3B	S165	P166L	166	Missense	proximal	1	no	8.021	5.161	EPSD	ICGC;COSMIC	6.007	Loss
CMGC_GSK_GSK3B_ST	P30291	WEE1	P49841	GSK3B	T173	P166L	166	Missense	distal	-7	no	7.749	7.751	EPSD	ICGC;COSMIC	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	P30291	WEE1	P49841	GSK3B	T173	T173P	173	Missense	central	0	yes	7.749	0.000	EPSD	ICGC;COSMIC	6.007	Loss
CMGC_GSK_GSK3B_ST	P30291	WEE1	P49841	GSK3B	S293	R294L	294	Missense	proximal	1	no	6.714	6.174	EPSD	ICGC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	P30291	WEE1	P49841	GSK3B	S293	S289T	289	Missense	distal	-4	no	6.714	6.379	EPSD	ICGC;COSMIC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	P30291	WEE1	P49841	GSK3B	S472	H466Y	466	Missense	distal	-6	no	9.090	9.038	EPSD	ICGC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	P30291	WEE1	P49841	GSK3B	S592	E587K	587	Missense	distal	-5	no	6.089	5.858	EPSD	ICGC;COSMIC	6.007	Loss
CMGC_GSK_GSK3B_ST	P30291	WEE1	P49841	GSK3B	S640	R639C	639	Missense	proximal	-1	no	5.932	6.033	EPSD	ICGC;COSMIC	6.007	Gain
CMGC_GSK_GSK3B_ST	Q14195	DPYSL3	P49841	GSK3B	S304	A298V	298	Missense	distal	-6	no	10.736	10.658	EPSD	ICGC;COSMIC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	Q14195	DPYSL3	P49841	GSK3B	S304	V302L	302	Missense	proximal	-2	no	10.736	10.694	EPSD	ICGC;COSMIC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	Q14195	DPYSL3	P49841	GSK3B	S304	P306L	306	Missense	proximal	2	no	10.736	10.351	EPSD	ICGC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	Q14195	DPYSL3	P49841	GSK3B	S304	A300T	300	Missense	distal	-4	no	10.736	11.560	EPSD	ICGC;COSMIC	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	Q14195	DPYSL3	P49841	GSK3B	S304	V302A	302	Missense	proximal	-2	no	10.736	10.434	EPSD	ICGC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	Q14195	DPYSL3	P49841	GSK3B	S308	P314Q	314	Missense	distal	6	no	8.188	8.182	EPSD	ICGC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	Q14195	DPYSL3	P49841	GSK3B	S308	V302L	302	Missense	distal	-6	no	8.188	8.254	EPSD	ICGC;COSMIC	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	Q14195	DPYSL3	P49841	GSK3B	S308	P306L	306	Missense	proximal	-2	no	8.188	7.857	EPSD	ICGC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	Q14195	DPYSL3	P49841	GSK3B	S308	V302A	302	Missense	distal	-6	no	8.188	8.266	EPSD	ICGC	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	Q14195	DPYSL3	P49841	GSK3B	S472	R467L	467	Missense	distal	-5	no	7.743	7.154	EPSD	ICGC;COSMIC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	Q14195	DPYSL3	P49841	GSK3B	S472	R467H	467	Missense	distal	-5	no	7.743	7.212	EPSD	ICGC;COSMIC;GDSC;CCLE	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	Q14195	DPYSL3	P49841	GSK3B	T509	A516E	516	Missense	distal	7	no	9.218	8.909	EPSD;PhosphoSitePlus	ICGC;COSMIC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	Q14195	DPYSL3	P49841	GSK3B	T509	T509N	509	Missense	central	0	yes	9.218	0.000	EPSD;PhosphoSitePlus	ICGC;COSMIC	6.007	Loss
CMGC_GSK_GSK3B_ST	Q14195	DPYSL3	P49841	GSK3B	T509	P502L	502	Missense	distal	-7	no	9.218	9.220	EPSD;PhosphoSitePlus	ICGC;COSMIC	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	Q14195	DPYSL3	P49841	GSK3B	T509	T507I	507	Missense	proximal	-2	no	9.218	9.180	EPSD;PhosphoSitePlus	ICGC;COSMIC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	Q14195	DPYSL3	P49841	GSK3B	T514	R520W	520	Missense	distal	6	no	10.212	10.201	PhosphoSitePlus;EPSD	ICGC;COSMIC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	Q14195	DPYSL3	P49841	GSK3B	T514	A516E	516	Missense	proximal	2	no	10.212	10.117	PhosphoSitePlus;EPSD	ICGC;COSMIC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	Q14195	DPYSL3	P49841	GSK3B	T514	T509N	509	Missense	distal	-5	no	10.212	9.631	PhosphoSitePlus;EPSD	ICGC;COSMIC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	Q14195	DPYSL3	P49841	GSK3B	T514	T507I	507	Missense	distal	-7	no	10.212	10.213	PhosphoSitePlus;EPSD	ICGC;COSMIC	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	Q14195	DPYSL3	P49841	GSK3B	S518	R520W	520	Missense	proximal	2	no	9.273	8.843	EPSD;PhosphoSitePlus	ICGC;COSMIC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	Q14195	DPYSL3	P49841	GSK3B	S518	A516E	516	Missense	proximal	-2	no	9.273	9.505	EPSD;PhosphoSitePlus	ICGC;COSMIC	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	Q14195	DPYSL3	P49841	GSK3B	S518	S522F	522	Missense	distal	4	no	9.273	5.659	EPSD;PhosphoSitePlus	ICGC	6.007	Loss
CMGC_GSK_GSK3B_ST	Q14195	DPYSL3	P49841	GSK3B	S522	R520W	520	Missense	proximal	-2	no	7.516	7.722	EPSD	ICGC;COSMIC	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	Q14195	DPYSL3	P49841	GSK3B	S522	P526L	526	Missense	distal	4	no	7.516	7.769	EPSD	ICGC;COSMIC	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	Q14195	DPYSL3	P49841	GSK3B	S522	A516E	516	Missense	distal	-6	no	7.516	7.443	EPSD	ICGC;COSMIC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	Q14195	DPYSL3	P49841	GSK3B	S522	S522F	522	Missense	central	0	yes	7.516	0.000	EPSD	ICGC	6.007	Loss
CMGC_GSK_GSK3B_ST	Q14195	DPYSL3	P49841	GSK3B	T524	P528T	528	Missense	distal	4	no	5.724	7.827	EPSD	ICGC	6.007	Gain
CMGC_GSK_GSK3B_ST	P54252	ATXN3	P49841	GSK3B	S29	P30S	30	Missense	proximal	1	no	8.285	4.440	EPSD	ICGC	6.007	Loss
CMGC_GSK_GSK3B_ST	Q15910	EZH2	P49841	GSK3B	S76	R81S	81	Missense	distal	5	no	7.147	6.831	EPSD	ICGC;COSMIC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	Q15910	EZH2	P49841	GSK3B	T345	P350S	350	Missense	distal	5	no	8.108	7.154	EPSD	ICGC;COSMIC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	Q15910	EZH2	P49841	GSK3B	T345	R342P	342	Missense	distal	-3	no	8.108	7.822	EPSD	ICGC;COSMIC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	Q15910	EZH2	P49841	GSK3B	T345	R349H	349	Missense	distal	4	no	8.108	7.390	EPSD	ICGC;COSMIC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	Q15910	EZH2	P49841	GSK3B	S363	S362N	362	Missense	proximal	-1	no	8.182	8.244	PhosphoSitePlus;EPSD	ICGC;COSMIC	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	Q15910	EZH2	P49841	GSK3B	S363	R357W	357	Missense	distal	-6	no	8.182	8.210	PhosphoSitePlus;EPSD	ICGC;COSMIC	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	Q15910	EZH2	P49841	GSK3B	S647	C642R	642	Missense	distal	-5	no	5.849	6.027	EPSD	ICGC;COSMIC	6.007	Gain
CMGC_GSK_GSK3B_ST	Q9Y6H5	SNCAIP	P49841	GSK3B	S80	E87K	87	Missense	distal	7	no	6.090	5.982	EPSD	ICGC;COSMIC	6.007	Loss
CMGC_GSK_GSK3B_ST	Q9Y6H5	SNCAIP	P49841	GSK3B	S239	K244N	244	Missense	distal	5	no	7.654	7.892	EPSD	ICGC	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	Q9Y6H5	SNCAIP	P49841	GSK3B	S674	S676L	676	Missense	proximal	2	no	6.055	6.115	EPSD	ICGC;COSMIC	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	Q9Y6H5	SNCAIP	P49841	GSK3B	S674	E677Q	677	Missense	distal	3	no	6.055	6.037	EPSD	ICGC;COSMIC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	Q9Y6H5	SNCAIP	P49841	GSK3B	S676	S676L	676	Missense	central	0	yes	6.253	0.000	EPSD	ICGC;COSMIC	6.007	Loss
CMGC_GSK_GSK3B_ST	Q9Y6H5	SNCAIP	P49841	GSK3B	S676	E677Q	677	Missense	proximal	1	no	6.253	6.818	EPSD	ICGC;COSMIC	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	Q9Y6H5	SNCAIP	P49841	GSK3B	S678	S676L	676	Missense	proximal	-2	no	8.105	8.031	EPSD	ICGC;COSMIC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	Q9Y6H5	SNCAIP	P49841	GSK3B	S678	E677Q	677	Missense	proximal	-1	no	8.105	8.010	EPSD	ICGC;COSMIC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	Q9Y6H5	SNCAIP	P49841	GSK3B	S747	P750L	750	Missense	distal	3	no	8.771	8.453	EPSD	ICGC;COSMIC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	Q9Y6H5	SNCAIP	P49841	GSK3B	S755	P750L	750	Missense	distal	-5	no	5.854	6.119	EPSD	ICGC;COSMIC	6.007	Gain
CMGC_GSK_GSK3B_ST	Q02156	PRKCE	P49841	GSK3B	T228	G222W	222	Missense	distal	-6	no	6.783	6.737	EPSD	ICGC;COSMIC;GDSC;CCLE	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	Q02156	PRKCE	P49841	GSK3B	T228	P229L	229	Missense	proximal	1	no	6.783	3.922	EPSD	ICGC;COSMIC	6.007	Loss
CMGC_GSK_GSK3B_ST	Q02156	PRKCE	P49841	GSK3B	T228	K225N	225	Missense	distal	-3	no	6.783	6.664	EPSD	ICGC;COSMIC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	Q02156	PRKCE	P49841	GSK3B	S234	P229L	229	Missense	distal	-5	no	7.285	7.551	EPSD	ICGC;COSMIC	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	Q02156	PRKCE	P49841	GSK3B	S261	G265E	265	Missense	distal	4	no	5.250	6.472	EPSD	ICGC;COSMIC	6.007	Gain
CMGC_GSK_GSK3B_ST	Q02156	PRKCE	P49841	GSK3B	T309	G307D	307	Missense	proximal	-2	no	6.743	6.845	EPSD	ICGC	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	Q02156	PRKCE	P49841	GSK3B	T309	V302L	302	Missense	distal	-7	no	6.743	6.721	EPSD	ICGC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	Q02156	PRKCE	P49841	GSK3B	T309	N315S	315	Missense	distal	6	no	6.743	6.749	EPSD	ICGC;COSMIC	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	Q02156	PRKCE	P49841	GSK3B	S388	Q385H	385	Missense	distal	-3	no	7.823	7.905	EPSD	ICGC;COSMIC	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	Q02156	PRKCE	P49841	GSK3B	T566	F567L	567	Missense	proximal	1	no	4.728	6.099	EPSD	ICGC	6.007	Gain
CMGC_GSK_GSK3B_ST	Q02156	PRKCE	P49841	GSK3B	T710	E714K	714	Missense	distal	4	no	6.249	5.067	EPSD	ICGC;COSMIC	6.007	Loss
CMGC_GSK_GSK3B_ST	Q02156	PRKCE	P49841	GSK3B	T710	E706G	706	Missense	distal	-4	no	6.249	6.418	EPSD	ICGC	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	P10914	IRF1	P49841	GSK3B	S282	P283Q	283	Missense	proximal	1	no	6.331	3.063	EPSD	ICGC;COSMIC	6.007	Loss
CMGC_GSK_GSK3B_ST	P10914	IRF1	P49841	GSK3B	S282	S282R	282	Missense	central	0	yes	6.331	0.000	EPSD	ICGC	6.007	Loss
CMGC_GSK_GSK3B_ST	P10914	IRF1	P49841	GSK3B	T311	W305L	305	Missense	distal	-6	no	6.650	6.679	EPSD	ICGC;COSMIC	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	P40337	VHL	P49841	GSK3B	S38	E32D	32	Missense	distal	-6	no	6.340	6.377	EPSD	ICGC	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	P40337	VHL	P49841	GSK3B	S38	E41K	41	Missense	distal	3	no	6.340	6.233	EPSD	ICGC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	P40337	VHL	P49841	GSK3B	S38	G34S	34	Missense	distal	-4	no	6.340	6.768	EPSD	ICGC;COSMIC	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	P40337	VHL	P49841	GSK3B	S68	P71R	71	Missense	distal	3	no	7.731	7.342	PhosphoSitePlus	ICGC;COSMIC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	P40337	VHL	P49841	GSK3B	S68	V74G	74	Missense	distal	6	no	7.731	7.737	PhosphoSitePlus	ICGC;COSMIC	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	P40337	VHL	P49841	GSK3B	S68	V62M	62	Missense	distal	-6	no	7.731	7.745	PhosphoSitePlus	ICGC	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	P40337	VHL	P49841	GSK3B	S68	S65L	65	Missense	distal	-3	no	7.731	7.740	PhosphoSitePlus	ICGC;COSMIC	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	P40337	VHL	P49841	GSK3B	S68	S65P	65	Missense	distal	-3	no	7.731	7.614	PhosphoSitePlus	ICGC;COSMIC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	P40337	VHL	P49841	GSK3B	S68	V74A	74	Missense	distal	6	no	7.731	7.739	PhosphoSitePlus	ICGC;COSMIC	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	P40337	VHL	P49841	GSK3B	S80	V74G	74	Missense	distal	-6	no	6.622	6.705	EPSD	ICGC;COSMIC	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	P40337	VHL	P49841	GSK3B	S80	N78I	78	Missense	proximal	-2	no	6.622	6.840	EPSD	ICGC;COSMIC	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	P40337	VHL	P49841	GSK3B	S80	N78S	78	Missense	proximal	-2	no	6.622	6.851	EPSD	ICGC;COSMIC	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	P40337	VHL	P49841	GSK3B	S80	V83F	83	Missense	distal	3	no	6.622	6.619	EPSD	ICGC;COSMIC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	P40337	VHL	P49841	GSK3B	S80	S80N	80	Missense	central	0	yes	6.622	0.000	EPSD	ICGC;COSMIC	6.007	Loss
CMGC_GSK_GSK3B_ST	P40337	VHL	P49841	GSK3B	S80	L85P	85	Missense	distal	5	no	6.622	7.903	EPSD	ICGC;COSMIC	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	P40337	VHL	P49841	GSK3B	S80	P86S	86	Missense	distal	6	no	6.622	6.620	EPSD	ICGC;COSMIC;GDSC;CCLE	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	P40337	VHL	P49841	GSK3B	S80	N78K	78	Missense	proximal	-2	no	6.622	6.716	EPSD	ICGC;COSMIC;CCLE	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	P40337	VHL	P49841	GSK3B	S80	V87L	87	Missense	distal	7	no	6.622	6.182	EPSD	ICGC;COSMIC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	P40337	VHL	P49841	GSK3B	S80	R79P	79	Missense	proximal	-1	no	6.622	6.815	EPSD	ICGC;COSMIC	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	P40337	VHL	P49841	GSK3B	S80	R79H	79	Missense	proximal	-1	no	6.622	6.708	EPSD	ICGC;COSMIC	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	P40337	VHL	P49841	GSK3B	S80	V74A	74	Missense	distal	-6	no	6.622	6.700	EPSD	ICGC;COSMIC	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	P40337	VHL	P49841	GSK3B	T100	L101P	101	Missense	proximal	1	no	4.030	6.890	EPSD	ICGC;COSMIC	6.007	Gain
CMGC_GSK_GSK3B_ST	Q01201	RELB	P49841	GSK3B	S8	S11P	11	Missense	distal	3	no	6.731	6.749	EPSD	ICGC;COSMIC	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	Q01201	RELB	P49841	GSK3B	S8	P13L	13	Missense	distal	5	no	6.731	5.450	EPSD	ICGC	6.007	Loss
CMGC_GSK_GSK3B_ST	Q01201	RELB	P49841	GSK3B	S8	P10Q	10	Missense	proximal	2	no	6.731	6.510	EPSD	ICGC;COSMIC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	Q01201	RELB	P49841	GSK3B	S44	V47F	47	Missense	distal	3	no	9.270	9.267	EPSD	ICGC;COSMIC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	Q04206	RELA	P49841	GSK3B	T71	R73C	73	Missense	proximal	2	no	6.110	5.599	EPSD	ICGC;COSMIC	6.007	Loss
CMGC_GSK_GSK3B_ST	Q04206	RELA	P49841	GSK3B	S319	G320R	320	Missense	proximal	1	no	5.638	6.512	EPSD	ICGC	6.007	Gain
CMGC_GSK_GSK3B_ST	Q04206	RELA	P49841	GSK3B	S468	D470E	470	Missense	proximal	2	no	8.201	8.022	PhosphoSitePlus	ICGC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	Q04206	RELA	P49841	GSK3B	T505	P510S	510	Missense	distal	5	no	6.176	5.222	EPSD	ICGC;COSMIC	6.007	Loss
CMGC_GSK_GSK3B_ST	Q04206	RELA	P49841	GSK3B	T505	T505K	505	Missense	central	0	yes	6.176	0.000	EPSD	ICGC	6.007	Loss
CMGC_GSK_GSK3B_ST	Q04206	RELA	P49841	GSK3B	S543	A538V	538	Missense	distal	-5	no	7.419	7.721	EPSD	ICGC;COSMIC	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	Q04206	RELA	P49841	GSK3B	S543	Q548P	548	Missense	distal	5	no	7.419	8.396	EPSD	ICGC;COSMIC	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	Q04206	RELA	P49841	GSK3B	S547	Q548P	548	Missense	proximal	1	no	7.432	10.700	EPSD	ICGC;COSMIC	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	P30279	CCND2	P49841	GSK3B	T280	P281S	281	Missense	proximal	1	no	9.037	5.192	PhosphoSitePlus	ICGC;COSMIC	6.007	Loss
CMGC_GSK_GSK3B_ST	P30279	CCND2	P49841	GSK3B	T280	V284E	284	Missense	distal	4	no	9.037	9.406	PhosphoSitePlus	ICGC;COSMIC	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	P30279	CCND2	P49841	GSK3B	T280	T280N	280	Missense	central	0	yes	9.037	0.000	PhosphoSitePlus	ICGC;COSMIC	6.007	Loss
CMGC_GSK_GSK3B_ST	P30279	CCND2	P49841	GSK3B	T280	T280I	280	Missense	central	0	yes	9.037	0.000	PhosphoSitePlus	ICGC;COSMIC	6.007	Loss
CMGC_GSK_GSK3B_ST	P30279	CCND2	P49841	GSK3B	T280	P281T	281	Missense	proximal	1	no	9.037	5.846	PhosphoSitePlus	ICGC;COSMIC	6.007	Loss
CMGC_GSK_GSK3B_ST	P30279	CCND2	P49841	GSK3B	T280	P281R	281	Missense	proximal	1	no	9.037	6.717	PhosphoSitePlus	ICGC;COSMIC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	P30279	CCND2	P49841	GSK3B	T280	D276Y	276	Missense	distal	-4	no	9.037	8.837	PhosphoSitePlus	ICGC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	P30279	CCND2	P49841	GSK3B	T280	V284L	284	Missense	distal	4	no	9.037	8.709	PhosphoSitePlus	ICGC;GDSC;CCLE	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	P30279	CCND2	P49841	GSK3B	T280	T280A	280	Missense	central	0	yes	9.037	0.000	PhosphoSitePlus	ICGC;COSMIC	6.007	Loss
CMGC_GSK_GSK3B_ST	Q16555	DPYSL2	P49841	GSK3B	S304	D310G	310	Missense	distal	6	no	10.759	10.763	EPSD	ICGC;COSMIC	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	Q16555	DPYSL2	P49841	GSK3B	S308	D310G	310	Missense	proximal	2	no	8.416	8.066	EPSD	ICGC;COSMIC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	Q16555	DPYSL2	P49841	GSK3B	T509	P515L	515	Missense	distal	6	no	8.948	8.941	PhosphoSitePlus;EPSD	ICGC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	Q16555	DPYSL2	P49841	GSK3B	T514	P515L	515	Missense	proximal	1	no	10.797	7.936	EPSD;PhosphoSitePlus	ICGC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	Q16555	DPYSL2	P49841	GSK3B	S517	P515L	515	Missense	proximal	-2	no	6.318	5.988	EPSD	ICGC	6.007	Loss
CMGC_GSK_GSK3B_ST	Q16555	DPYSL2	P49841	GSK3B	S518	P515L	515	Missense	distal	-3	no	8.398	8.524	EPSD;PhosphoSitePlus	ICGC	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	Q16555	DPYSL2	P49841	GSK3B	S522	P515L	515	Missense	distal	-7	no	7.344	7.346	EPSD	ICGC	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	P17676	CEBPB	P49841	GSK3B	S76	I73M	73	Missense	distal	-3	no	9.406	9.264	EPSD	ICGC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	P17676	CEBPB	P49841	GSK3B	S141	L142P	142	Missense	proximal	1	no	3.632	6.493	EPSD	ICGC;COSMIC	6.007	Gain
CMGC_GSK_GSK3B_ST	P17676	CEBPB	P49841	GSK3B	S221	L224I	224	Missense	distal	3	no	7.110	6.990	EPSD	ICGC;COSMIC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	P17676	CEBPB	P49841	GSK3B	S223	L224I	224	Missense	proximal	1	no	7.190	6.169	PhosphoSitePlus	ICGC;COSMIC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	P17676	CEBPB	P49841	GSK3B	S225	L224I	224	Missense	proximal	-1	no	7.713	7.638	EPSD	ICGC;COSMIC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	P17676	CEBPB	P49841	GSK3B	S227	L224I	224	Missense	distal	-3	no	9.219	9.323	EPSD	ICGC;COSMIC	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	P17676	CEBPB	P49841	GSK3B	S231	L224I	224	Missense	distal	-7	no	12.128	12.155	EPSD	ICGC;COSMIC	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	P17676	CEBPB	P49841	GSK3B	S231	P238H	238	Missense	distal	7	no	12.128	12.817	EPSD	ICGC;COSMIC	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	P17676	CEBPB	P49841	GSK3B	T235	P238H	238	Missense	distal	3	no	7.921	7.875	EPSD	ICGC;COSMIC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	P17676	CEBPB	P49841	GSK3B	S237	P238H	238	Missense	proximal	1	no	6.521	2.820	EPSD	ICGC;COSMIC	6.007	Loss
CMGC_GSK_GSK3B_ST	Q08050	FOXM1	P49841	GSK3B	S35	S41C	41	Missense	distal	6	no	6.762	6.749	EPSD	ICGC;COSMIC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	Q08050	FOXM1	P49841	GSK3B	S331	P335T	335	Missense	distal	4	no	5.277	7.379	EPSD	ICGC	6.007	Gain
CMGC_GSK_GSK3B_ST	Q08050	FOXM1	P49841	GSK3B	S331	P335S	335	Missense	distal	4	no	5.277	8.248	EPSD	ICGC	6.007	Gain
CMGC_GSK_GSK3B_ST	Q08050	FOXM1	P49841	GSK3B	S505	P509T	509	Missense	distal	4	no	4.036	6.138	EPSD	ICGC;COSMIC	6.007	Gain
CMGC_GSK_GSK3B_ST	Q08050	FOXM1	P49841	GSK3B	S506	P509T	509	Missense	distal	3	no	6.083	6.033	EPSD	ICGC;COSMIC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	Q08050	FOXM1	P49841	GSK3B	S508	P509T	509	Missense	proximal	1	no	6.417	3.226	EPSD	ICGC;COSMIC	6.007	Loss
CMGC_GSK_GSK3B_ST	Q08050	FOXM1	P49841	GSK3B	T510	P509T	509	Missense	proximal	-1	no	7.126	6.995	EPSD	ICGC;COSMIC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	Q08050	FOXM1	P49841	GSK3B	T627	G634R	634	Missense	distal	7	no	6.076	6.494	EPSD	ICGC	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	Q08050	FOXM1	P49841	GSK3B	S638	G634R	634	Missense	distal	-4	no	9.401	8.643	EPSD	ICGC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	P24385	CCND1	P49841	GSK3B	T286	D289N	289	Missense	distal	3	no	8.992	8.945	PhosphoSitePlus	ICGC;COSMIC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	P24385	CCND1	P49841	GSK3B	T286	E280D	280	Missense	distal	-6	no	8.992	9.028	PhosphoSitePlus	ICGC	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	P24385	CCND1	P49841	GSK3B	T286	P287A	287	Missense	proximal	1	no	8.992	5.259	PhosphoSitePlus	ICGC;COSMIC;GDSC;CCLE	6.007	Loss
CMGC_GSK_GSK3B_ST	Q07817	BCL2L1	P49841	GSK3B	T47	E44D	44	Missense	distal	-3	no	6.006	6.039	EPSD	ICGC;COSMIC	6.007	Gain
CMGC_GSK_GSK3B_ST	Q07817	BCL2L1	P49841	GSK3B	T115	S122R	122	Missense	distal	7	no	6.249	6.686	EPSD	ICGC	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	Q07817	BCL2L1	P49841	GSK3B	T115	T118K	118	Missense	distal	3	no	6.249	6.155	EPSD	ICGC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	Q07817	BCL2L1	P49841	GSK3B	T115	T109K	109	Missense	distal	-6	no	6.249	6.244	EPSD	ICGC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	P41236	PPP1R2	P49841	GSK3B	S24	Q31K	31	Missense	distal	7	no	6.267	6.108	EPSD	ICGC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	P41236	PPP1R2	P49841	GSK3B	T73	D69G	69	Missense	distal	-4	no	9.410	9.582	PhosphoSitePlus	ICGC	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	P41236	PPP1R2	P49841	GSK3B	T177	E172K	172	Missense	distal	-5	no	6.008	5.777	EPSD	ICGC;COSMIC	6.007	Loss
CMGC_GSK_GSK3B_ST	P41236	PPP1R2	P49841	GSK3B	S192	T185K	185	Missense	distal	-7	no	6.413	6.407	EPSD	ICGC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	Q16236	NFE2L2	P49841	GSK3B	T211	M212I	212	Missense	proximal	1	no	6.279	5.985	EPSD	ICGC;COSMIC	6.007	Loss
CMGC_GSK_GSK3B_ST	Q16236	NFE2L2	P49841	GSK3B	S347	L348I	348	Missense	proximal	1	no	8.774	7.754	PhosphoSitePlus;EPSD	ICGC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	Q16236	NFE2L2	P49841	GSK3B	S351	L348I	348	Missense	distal	-3	no	9.109	9.213	EPSD	ICGC	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	P13807	GYS1	P49841	GSK3B	T6	P2T	2	Missense	distal	-4	no	5.856	6.083	EPSD	ICGC;COSMIC	6.007	Gain
CMGC_GSK_GSK3B_ST	P13807	GYS1	P49841	GSK3B	T204	L208S	208	Missense	distal	4	no	3.307	6.025	EPSD	ICGC	6.007	Gain
CMGC_GSK_GSK3B_ST	P13051	UNG	P49841	GSK3B	S12	L7F	7	Missense	distal	-5	no	7.468	7.919	EPSD	ICGC	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	P13051	UNG	P49841	GSK3B	S14	L7F	7	Missense	distal	-7	no	7.637	7.647	EPSD	ICGC	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	P13051	UNG	P49841	GSK3B	T60	P62H	62	Missense	proximal	2	no	10.640	9.871	EPSD;PhosphoSitePlus	ICGC;COSMIC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	P13051	UNG	P49841	GSK3B	T60	P65L	65	Missense	distal	5	no	10.640	9.360	EPSD;PhosphoSitePlus	ICGC;COSMIC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	P13051	UNG	P49841	GSK3B	S63	P62H	62	Missense	proximal	-1	no	6.113	6.005	EPSD	ICGC;COSMIC	6.007	Loss
CMGC_GSK_GSK3B_ST	P13051	UNG	P49841	GSK3B	S63	P65L	65	Missense	proximal	2	no	6.113	5.728	EPSD	ICGC;COSMIC	6.007	Loss
CMGC_GSK_GSK3B_ST	P13051	UNG	P49841	GSK3B	S64	P62H	62	Missense	proximal	-2	no	8.358	7.996	PhosphoSitePlus;EPSD	ICGC;COSMIC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	P13051	UNG	P49841	GSK3B	S64	P65L	65	Missense	proximal	1	no	8.358	5.498	PhosphoSitePlus;EPSD	ICGC;COSMIC	6.007	Loss
CMGC_GSK_GSK3B_ST	Q14494	NFE2L1	P49841	GSK3B	S379	E383K	383	Missense	distal	4	no	7.123	5.942	PhosphoSitePlus	ICGC;COSMIC	6.007	Loss
CMGC_GSK_GSK3B_ST	Q7KZI7	MARK2	P49841	GSK3B	S26	S32F	32	Missense	distal	6	no	6.609	6.596	EPSD	ICGC;COSMIC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	Q7KZI7	MARK2	P49841	GSK3B	S26	L21F	21	Missense	distal	-5	no	6.609	7.059	EPSD	ICGC;COSMIC	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	Q7KZI7	MARK2	P49841	GSK3B	S212	A216S	216	Missense	distal	4	no	11.034	13.445	PhosphoSitePlus	ICGC	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	Q7KZI7	MARK2	P49841	GSK3B	S456	L461F	461	Missense	distal	5	no	6.831	6.491	EPSD	ICGC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	Q7KZI7	MARK2	P49841	GSK3B	S456	P454S	454	Missense	proximal	-2	no	6.831	6.575	EPSD	ICGC;COSMIC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	Q7KZI7	MARK2	P49841	GSK3B	T467	L461F	461	Missense	distal	-6	no	7.070	7.018	EPSD	ICGC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	O00327	ARNTL	P49841	GSK3B	S17	P18Q	18	Missense	proximal	1	no	10.639	7.371	EPSD;PhosphoSitePlus	ICGC;COSMIC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	O00327	ARNTL	P49841	GSK3B	S17	P20S	20	Missense	distal	3	no	10.639	10.621	EPSD;PhosphoSitePlus	ICGC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	O00327	ARNTL	P49841	GSK3B	S17	D22N	22	Missense	distal	5	no	10.639	10.213	EPSD;PhosphoSitePlus	ICGC;COSMIC;GDSC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	O00327	ARNTL	P49841	GSK3B	T21	P18Q	18	Missense	distal	-3	no	7.717	7.864	PhosphoSitePlus;EPSD	ICGC;COSMIC	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	O00327	ARNTL	P49841	GSK3B	T21	P20S	20	Missense	proximal	-1	no	7.717	7.661	PhosphoSitePlus;EPSD	ICGC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	O00327	ARNTL	P49841	GSK3B	T21	D22N	22	Missense	proximal	1	no	7.717	5.301	PhosphoSitePlus;EPSD	ICGC;COSMIC;GDSC	6.007	Loss
CMGC_GSK_GSK3B_ST	O00327	ARNTL	P49841	GSK3B	S520	T525M	525	Missense	distal	5	no	6.514	6.398	EPSD	ICGC;COSMIC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	O00327	ARNTL	P49841	GSK3B	T527	T525M	525	Missense	proximal	-2	no	8.139	7.781	EPSD	ICGC;COSMIC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	Q13887	KLF5	P49841	GSK3B	S303	P302S	302	Missense	proximal	-1	no	12.612	12.556	PhosphoSitePlus	ICGC;COSMIC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	Q13887	KLF5	P49841	GSK3B	S303	S303A	303	Missense	central	0	yes	12.612	0.000	PhosphoSitePlus	ICGC;COSMIC	6.007	Loss
CMGC_GSK_GSK3B_ST	Q13887	KLF5	P49841	GSK3B	S303	P301T	301	Missense	proximal	-2	no	12.612	12.383	PhosphoSitePlus	ICGC;COSMIC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	Q13887	KLF5	P49841	GSK3B	S303	P309L	309	Missense	distal	6	no	12.612	12.606	PhosphoSitePlus	ICGC;COSMIC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	Q13887	KLF5	P49841	GSK3B	S303	P305R	305	Missense	proximal	2	no	12.612	12.187	PhosphoSitePlus	ICGC;COSMIC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	Q13887	KLF5	P49841	GSK3B	T323	M318R	318	Missense	distal	-5	no	7.049	7.444	EPSD	ICGC;COSMIC	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	O15516	CLOCK	P49841	GSK3B	S427	S427R	427	Missense	central	0	yes	9.116	0.000	PhosphoSitePlus	ICGC	6.007	Loss
CMGC_GSK_GSK3B_ST	O15516	CLOCK	P49841	GSK3B	S427	P428R	428	Missense	proximal	1	no	9.116	6.796	PhosphoSitePlus	ICGC;COSMIC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	O15516	CLOCK	P49841	GSK3B	T429	S427R	427	Missense	proximal	-2	no	7.798	7.682	EPSD	ICGC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	O15516	CLOCK	P49841	GSK3B	T429	P428R	428	Missense	proximal	-1	no	7.798	7.604	EPSD	ICGC;COSMIC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	O15516	CLOCK	P49841	GSK3B	T429	R435L	435	Missense	distal	6	no	7.798	7.797	EPSD	ICGC;COSMIC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	O15516	CLOCK	P49841	GSK3B	S433	S427R	427	Missense	distal	-6	no	7.203	7.146	EPSD	ICGC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	O15516	CLOCK	P49841	GSK3B	S433	P428R	428	Missense	distal	-5	no	7.203	8.057	EPSD	ICGC;COSMIC	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	O15516	CLOCK	P49841	GSK3B	S433	R435L	435	Missense	proximal	2	no	7.203	7.245	EPSD	ICGC;COSMIC	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	O15516	CLOCK	P49841	GSK3B	S437	R435L	435	Missense	proximal	-2	no	7.996	8.038	EPSD	ICGC;COSMIC	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	O15516	CLOCK	P49841	GSK3B	T451	T453N	453	Missense	proximal	2	no	7.186	6.527	EPSD	ICGC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	O15516	CLOCK	P49841	GSK3B	T451	D458Y	458	Missense	distal	7	no	7.186	7.573	EPSD	ICGC	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	O15516	CLOCK	P49841	GSK3B	T451	P456L	456	Missense	distal	5	no	7.186	5.905	EPSD	ICGC;COSMIC	6.007	Loss
CMGC_GSK_GSK3B_ST	O15516	CLOCK	P49841	GSK3B	T457	T459K	459	Missense	proximal	2	no	7.371	7.197	EPSD	ICGC;COSMIC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	O15516	CLOCK	P49841	GSK3B	T457	S460R	460	Missense	distal	3	no	7.371	7.000	EPSD	ICGC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	O15516	CLOCK	P49841	GSK3B	T457	T453N	453	Missense	distal	-4	no	7.371	6.409	EPSD	ICGC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	O15516	CLOCK	P49841	GSK3B	T457	D458Y	458	Missense	proximal	1	no	7.371	7.156	EPSD	ICGC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	O15516	CLOCK	P49841	GSK3B	T457	P456L	456	Missense	proximal	-1	no	7.371	7.239	EPSD	ICGC;COSMIC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	O15516	CLOCK	P49841	GSK3B	S836	P840T	840	Missense	distal	4	no	6.348	8.451	EPSD	ICGC	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	O15516	CLOCK	P49841	GSK3B	S836	H832N	832	Missense	distal	-4	no	6.348	6.139	EPSD	ICGC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	P30281	CCND3	P49841	GSK3B	S259	S259A	259	Missense	central	0	yes	7.159	0.000	EPSD	ICGC;COSMIC	6.007	Loss
CMGC_GSK_GSK3B_ST	P30281	CCND3	P49841	GSK3B	S259	A266E	266	Missense	distal	7	no	7.159	6.850	EPSD	ICGC;COSMIC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	P30281	CCND3	P49841	GSK3B	S259	S262I	262	Missense	distal	3	no	7.159	6.739	EPSD	ICGC;COSMIC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	P30281	CCND3	P49841	GSK3B	S264	S259A	259	Missense	distal	-5	no	6.434	6.712	EPSD	ICGC;COSMIC	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	P30281	CCND3	P49841	GSK3B	S264	A266E	266	Missense	proximal	2	no	6.434	6.339	EPSD	ICGC;COSMIC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	P30281	CCND3	P49841	GSK3B	S264	S262I	262	Missense	proximal	-2	no	6.434	6.424	EPSD	ICGC;COSMIC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	P30281	CCND3	P49841	GSK3B	S279	T283P	283	Missense	distal	4	no	7.717	5.615	EPSD	ICGC;COSMIC	6.007	Loss
CMGC_GSK_GSK3B_ST	P30281	CCND3	P49841	GSK3B	S279	D286A	286	Missense	distal	7	no	7.717	8.011	EPSD	ICGC	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	P30281	CCND3	P49841	GSK3B	S282	T283P	283	Missense	proximal	1	no	4.904	8.095	EPSD	ICGC;COSMIC	6.007	Gain
CMGC_GSK_GSK3B_ST	P30281	CCND3	P49841	GSK3B	T283	A289D	289	Missense	distal	6	no	7.524	7.519	PhosphoSitePlus	ICGC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	P30281	CCND3	P49841	GSK3B	T283	I290K	290	Missense	distal	7	no	7.524	7.119	PhosphoSitePlus	ICGC;COSMIC;CCLE	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	P30281	CCND3	P49841	GSK3B	T283	I290T	290	Missense	distal	7	no	7.524	7.130	PhosphoSitePlus	ICGC;COSMIC;CCLE	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	P30281	CCND3	P49841	GSK3B	T283	T283P	283	Missense	central	0	yes	7.524	0.000	PhosphoSitePlus	ICGC;COSMIC	6.007	Loss
CMGC_GSK_GSK3B_ST	P30281	CCND3	P49841	GSK3B	T283	D286A	286	Missense	distal	3	no	7.524	7.092	PhosphoSitePlus	ICGC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	P53805	RCAN1	P49841	GSK3B	S163	P168T	168	Missense	distal	5	no	12.223	11.246	PhosphoSitePlus	ICGC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	P53805	RCAN1	P49841	GSK3B	S167	P168T	168	Missense	proximal	1	no	6.637	3.446	EPSD	ICGC	6.007	Loss
CMGC_GSK_GSK3B_ST	P53805	RCAN1	P49841	GSK3B	T208	H202R	202	Missense	distal	-6	no	6.191	6.168	EPSD	ICGC;COSMIC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	O15033	AREL1	P49841	GSK3B	T343	S339F	339	Missense	distal	-4	no	8.880	7.726	EPSD	ICGC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	O15033	AREL1	P49841	GSK3B	T343	P350T	350	Missense	distal	7	no	8.880	8.884	EPSD	ICGC	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	O15033	AREL1	P49841	GSK3B	T343	E340K	340	Missense	distal	-3	no	8.880	8.890	EPSD	ICGC;COSMIC	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	O15033	AREL1	P49841	GSK3B	T343	P344S	344	Missense	proximal	1	no	8.880	5.035	EPSD	ICGC	6.007	Loss
CMGC_GSK_GSK3B_ST	P04198	MYCN	P49841	GSK3B	T259	T259N	259	Missense	central	0	yes	6.316	0.000	EPSD	ICGC;COSMIC	6.007	Loss
CMGC_GSK_GSK3B_ST	P04198	MYCN	P49841	GSK3B	S261	T259N	259	Missense	proximal	-2	no	6.766	6.510	EPSD	ICGC;COSMIC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	P04198	MYCN	P49841	GSK3B	S287	R285W	285	Missense	proximal	-2	no	5.933	6.138	EPSD	ICGC;COSMIC	6.007	Gain
CMGC_GSK_GSK3B_ST	P04198	MYCN	P49841	GSK3B	S355	R357C	357	Missense	proximal	2	no	7.011	6.500	EPSD	ICGC;COSMIC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	P04198	MYCN	P49841	GSK3B	S355	P358L	358	Missense	distal	3	no	7.011	6.692	EPSD	ICGC;COSMIC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	P04198	MYCN	P49841	GSK3B	S355	P356A	356	Missense	proximal	1	no	7.011	3.278	EPSD	ICGC;COSMIC;CCLE	6.007	Loss
CMGC_GSK_GSK3B_ST	P04198	MYCN	P49841	GSK3B	S355	S361I	361	Missense	distal	6	no	7.011	7.010	EPSD	ICGC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	P04198	MYCN	P49841	GSK3B	S355	P356S	356	Missense	proximal	1	no	7.011	3.166	EPSD	ICGC	6.007	Loss
CMGC_GSK_GSK3B_ST	P04198	MYCN	P49841	GSK3B	S371	S369I	369	Missense	proximal	-2	no	9.672	9.662	EPSD	ICGC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	P04198	MYCN	P49841	GSK3B	S371	S369R	369	Missense	proximal	-2	no	9.672	9.557	EPSD	ICGC;COSMIC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	P04198	MYCN	P49841	GSK3B	S375	R382H	382	Missense	distal	7	no	5.954	6.142	EPSD	ICGC;COSMIC	6.007	Gain
CMGC_GSK_GSK3B_ST	P98170	XIAP	P49841	GSK3B	S40	N35D	35	Missense	distal	-5	no	5.729	6.294	EPSD	ICGC;COSMIC	6.007	Gain
CMGC_GSK_GSK3B_ST	P98170	XIAP	P49841	GSK3B	T180	A187S	187	Missense	distal	7	no	7.708	7.360	PhosphoSitePlus	ICGC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	P98170	XIAP	P49841	GSK3B	T180	H178R	178	Missense	proximal	-2	no	7.708	7.698	PhosphoSitePlus	ICGC;COSMIC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	P98170	XIAP	P49841	GSK3B	S430	Q423P	423	Missense	distal	-7	no	6.390	6.374	EPSD	ICGC;COSMIC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	P54132	BLM	P49841	GSK3B	S131	A135S	135	Missense	distal	4	no	5.966	8.378	EPSD	ICGC	6.007	Gain
CMGC_GSK_GSK3B_ST	P54132	BLM	P49841	GSK3B	S144	S147Y	147	Missense	distal	3	no	7.561	7.138	EPSD	ICGC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	P54132	BLM	P49841	GSK3B	S304	T298M	298	Missense	distal	-6	no	7.653	7.658	EPSD	ICGC;COSMIC;GDSC	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	P54132	BLM	P49841	GSK3B	S304	S304Y	304	Missense	central	0	yes	7.653	0.000	EPSD	ICGC	6.007	Loss
CMGC_GSK_GSK3B_ST	P54132	BLM	P49841	GSK3B	S434	P438S	438	Missense	distal	4	no	5.255	8.226	EPSD	ICGC;COSMIC	6.007	Gain
CMGC_GSK_GSK3B_ST	P54132	BLM	P49841	GSK3B	S456	N454T	454	Missense	proximal	-2	no	5.998	6.254	EPSD	ICGC	6.007	Gain
CMGC_GSK_GSK3B_ST	P54132	BLM	P49841	GSK3B	S456	S449C	449	Missense	distal	-7	no	5.998	6.021	EPSD	ICGC;COSMIC	6.007	Gain
CMGC_GSK_GSK3B_ST	P54132	BLM	P49841	GSK3B	S601	S601Y	601	Missense	central	0	yes	6.085	0.000	EPSD	ICGC;COSMIC	6.007	Loss
CMGC_GSK_GSK3B_ST	P54132	BLM	P49841	GSK3B	S706	A703V	703	Missense	distal	-3	no	7.890	8.036	EPSD	ICGC;COSMIC	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	P54132	BLM	P49841	GSK3B	S706	V705I	705	Missense	proximal	-1	no	7.890	7.692	EPSD	ICGC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	P54132	BLM	P49841	GSK3B	S706	V705F	705	Missense	proximal	-1	no	7.890	7.711	EPSD	ICGC;COSMIC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	P54132	BLM	P49841	GSK3B	S706	C704F	704	Missense	proximal	-2	no	7.890	7.871	EPSD	ICGC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	P54132	BLM	P49841	GSK3B	S706	T710N	710	Missense	distal	4	no	7.890	5.148	EPSD	ICGC	6.007	Loss
CMGC_GSK_GSK3B_ST	P54132	BLM	P49841	GSK3B	S706	S706Y	706	Missense	central	0	yes	7.890	0.000	EPSD	ICGC	6.007	Loss
CMGC_GSK_GSK3B_ST	P54132	BLM	P49841	GSK3B	S706	P707S	707	Missense	proximal	1	no	7.890	4.045	EPSD	ICGC;COSMIC;GDSC	6.007	Loss
CMGC_GSK_GSK3B_ST	P54132	BLM	P49841	GSK3B	S714	V721L	721	Missense	distal	7	no	11.395	10.955	EPSD	ICGC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	P54132	BLM	P49841	GSK3B	S714	T710N	710	Missense	distal	-4	no	11.395	10.433	EPSD	ICGC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	P54132	BLM	P49841	GSK3B	S714	P707S	707	Missense	distal	-7	no	11.395	11.396	EPSD	ICGC;COSMIC;GDSC	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	P54132	BLM	P49841	GSK3B	S1138	R1144S	1144	Missense	distal	6	no	6.050	6.055	EPSD	ICGC;COSMIC	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	P54132	BLM	P49841	GSK3B	S1138	A1142T	1142	Missense	distal	4	no	6.050	7.593	EPSD	ICGC	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	P54132	BLM	P49841	GSK3B	S1138	R1139L	1139	Missense	proximal	1	no	6.050	5.510	EPSD	ICGC;COSMIC	6.007	Loss
CMGC_GSK_GSK3B_ST	P54132	BLM	P49841	GSK3B	S1138	G1132E	1132	Missense	distal	-6	no	6.050	5.972	EPSD	ICGC	6.007	Loss
CMGC_GSK_GSK3B_ST	P54132	BLM	P49841	GSK3B	S1252	A1250S	1250	Missense	proximal	-2	no	5.804	6.139	EPSD	ICGC	6.007	Gain
CMGC_GSK_GSK3B_ST	P54132	BLM	P49841	GSK3B	S1286	I1279V	1279	Missense	distal	-7	no	6.378	6.372	EPSD	ICGC;COSMIC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	P54132	BLM	P49841	GSK3B	S1290	P1297Q	1297	Missense	distal	7	no	9.665	9.819	EPSD	ICGC;COSMIC	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	P54132	BLM	P49841	GSK3B	S1296	P1297Q	1297	Missense	proximal	1	no	7.903	4.635	EPSD	ICGC;COSMIC	6.007	Loss
CMGC_GSK_GSK3B_ST	P54132	BLM	P49841	GSK3B	S1300	P1297Q	1297	Missense	distal	-3	no	9.897	10.044	EPSD	ICGC;COSMIC	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	P54132	BLM	P49841	GSK3B	S1379	S1375G	1375	Missense	distal	-4	no	6.324	5.896	EPSD	ICGC	6.007	Loss
CMGC_GSK_GSK3B_ST	P54132	BLM	P49841	GSK3B	S1379	G1378V	1378	Missense	proximal	-1	no	6.324	6.366	EPSD	ICGC	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	P54132	BLM	P49841	GSK3B	S1390	G1397E	1397	Missense	distal	7	no	6.067	6.086	EPSD	ICGC	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	E9PAV3	NACA	P49841	GSK3B	S271	L278F	278	Missense	distal	7	no	7.492	7.583	EPSD	ICGC	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	E9PAV3	NACA	P49841	GSK3B	S340	V336E	336	Missense	distal	-4	no	6.490	7.127	EPSD	ICGC;COSMIC	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	E9PAV3	NACA	P49841	GSK3B	S340	T338N	338	Missense	proximal	-2	no	6.490	6.234	EPSD	ICGC;COSMIC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	E9PAV3	NACA	P49841	GSK3B	S340	D342G	342	Missense	proximal	2	no	6.490	6.140	EPSD	ICGC;COSMIC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	E9PAV3	NACA	P49841	GSK3B	S340	D342H	342	Missense	proximal	2	no	6.490	6.073	EPSD	ICGC;COSMIC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	E9PAV3	NACA	P49841	GSK3B	S340	G347V	347	Missense	distal	7	no	6.490	6.896	EPSD	ICGC;COSMIC	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	E9PAV3	NACA	P49841	GSK3B	S506	P512H	512	Missense	distal	6	no	6.061	6.049	EPSD	ICGC;COSMIC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	E9PAV3	NACA	P49841	GSK3B	S506	P507H	507	Missense	proximal	1	no	6.061	2.361	EPSD	ICGC;COSMIC	6.007	Loss
CMGC_GSK_GSK3B_ST	E9PAV3	NACA	P49841	GSK3B	S579	P583T	583	Missense	distal	4	no	6.972	9.074	EPSD	ICGC	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	E9PAV3	NACA	P49841	GSK3B	S579	P583L	583	Missense	distal	4	no	6.972	7.225	EPSD	ICGC	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	E9PAV3	NACA	P49841	GSK3B	S579	P586H	586	Missense	distal	7	no	6.972	7.661	EPSD	ICGC;COSMIC	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	E9PAV3	NACA	P49841	GSK3B	S585	P583T	583	Missense	proximal	-2	no	9.009	8.780	EPSD	ICGC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	E9PAV3	NACA	P49841	GSK3B	S585	L590I	590	Missense	distal	5	no	9.009	8.669	EPSD	ICGC;COSMIC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	E9PAV3	NACA	P49841	GSK3B	S585	P583L	583	Missense	proximal	-2	no	9.009	8.679	EPSD	ICGC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	E9PAV3	NACA	P49841	GSK3B	S585	P586H	586	Missense	proximal	1	no	9.009	5.309	EPSD	ICGC;COSMIC	6.007	Loss
CMGC_GSK_GSK3B_ST	E9PAV3	NACA	P49841	GSK3B	S829	S834L	834	Missense	distal	5	no	8.849	8.523	EPSD	ICGC;COSMIC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	E9PAV3	NACA	P49841	GSK3B	S849	S846Y	846	Missense	distal	-3	no	6.865	7.005	EPSD	ICGC;COSMIC	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	E9PAV3	NACA	P49841	GSK3B	S849	T853M	853	Missense	distal	4	no	6.865	5.499	EPSD	ICGC;COSMIC	6.007	Loss
CMGC_GSK_GSK3B_ST	E9PAV3	NACA	P49841	GSK3B	S849	T852M	852	Missense	distal	3	no	6.865	6.706	EPSD	ICGC;COSMIC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	E9PAV3	NACA	P49841	GSK3B	T853	S860P	860	Missense	distal	7	no	6.255	6.192	EPSD	ICGC;COSMIC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	E9PAV3	NACA	P49841	GSK3B	T853	S846Y	846	Missense	distal	-7	no	6.255	6.284	EPSD	ICGC;COSMIC	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	E9PAV3	NACA	P49841	GSK3B	T853	P858S	858	Missense	distal	5	no	6.255	5.301	EPSD	ICGC;COSMIC	6.007	Loss
CMGC_GSK_GSK3B_ST	E9PAV3	NACA	P49841	GSK3B	T853	T853M	853	Missense	central	0	yes	6.255	0.000	EPSD	ICGC;COSMIC	6.007	Loss
CMGC_GSK_GSK3B_ST	E9PAV3	NACA	P49841	GSK3B	T853	T852M	852	Missense	proximal	-1	no	6.255	6.280	EPSD	ICGC;COSMIC	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	E9PAV3	NACA	P49841	GSK3B	T853	P858L	858	Missense	distal	5	no	6.255	4.975	EPSD	ICGC	6.007	Loss
CMGC_GSK_GSK3B_ST	E9PAV3	NACA	P49841	GSK3B	S855	S860P	860	Missense	distal	5	no	6.310	7.264	EPSD	ICGC;COSMIC	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	E9PAV3	NACA	P49841	GSK3B	S855	P859T	859	Missense	distal	4	no	6.310	8.412	EPSD	ICGC	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	E9PAV3	NACA	P49841	GSK3B	S855	P858S	858	Missense	distal	3	no	6.310	6.292	EPSD	ICGC;COSMIC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	E9PAV3	NACA	P49841	GSK3B	S855	T853M	853	Missense	proximal	-2	no	6.310	5.952	EPSD	ICGC;COSMIC	6.007	Loss
CMGC_GSK_GSK3B_ST	E9PAV3	NACA	P49841	GSK3B	S855	T852M	852	Missense	distal	-3	no	6.310	6.257	EPSD	ICGC;COSMIC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	E9PAV3	NACA	P49841	GSK3B	S855	P858L	858	Missense	distal	3	no	6.310	5.991	EPSD	ICGC	6.007	Loss
CMGC_GSK_GSK3B_ST	E9PAV3	NACA	P49841	GSK3B	T857	S860P	860	Missense	distal	3	no	7.179	7.197	EPSD	ICGC;COSMIC	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	E9PAV3	NACA	P49841	GSK3B	T857	P859T	859	Missense	proximal	2	no	7.179	6.862	EPSD	ICGC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	E9PAV3	NACA	P49841	GSK3B	T857	P858S	858	Missense	proximal	1	no	7.179	3.334	EPSD	ICGC;COSMIC	6.007	Loss
CMGC_GSK_GSK3B_ST	E9PAV3	NACA	P49841	GSK3B	T857	T853M	853	Missense	distal	-4	no	7.179	6.455	EPSD	ICGC;COSMIC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	E9PAV3	NACA	P49841	GSK3B	T857	T852M	852	Missense	distal	-5	no	7.179	7.192	EPSD	ICGC;COSMIC	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	E9PAV3	NACA	P49841	GSK3B	T857	P858L	858	Missense	proximal	1	no	7.179	4.319	EPSD	ICGC	6.007	Loss
CMGC_GSK_GSK3B_ST	E9PAV3	NACA	P49841	GSK3B	S860	S860P	860	Missense	central	0	yes	9.061	0.000	EPSD	ICGC;COSMIC	6.007	Loss
CMGC_GSK_GSK3B_ST	E9PAV3	NACA	P49841	GSK3B	S860	P859T	859	Missense	proximal	-1	no	9.061	8.930	EPSD	ICGC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	E9PAV3	NACA	P49841	GSK3B	S860	P867S	867	Missense	distal	7	no	9.061	9.124	EPSD	ICGC	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	E9PAV3	NACA	P49841	GSK3B	S860	P858S	858	Missense	proximal	-2	no	9.061	8.805	EPSD	ICGC;COSMIC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	E9PAV3	NACA	P49841	GSK3B	S860	T853M	853	Missense	distal	-7	no	9.061	9.055	EPSD	ICGC;COSMIC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	E9PAV3	NACA	P49841	GSK3B	S860	P858L	858	Missense	proximal	-2	no	9.061	8.731	EPSD	ICGC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	E9PAV3	NACA	P49841	GSK3B	T871	P867S	867	Missense	distal	-4	no	5.570	6.134	EPSD	ICGC	6.007	Gain
CMGC_GSK_GSK3B_ST	E9PAV3	NACA	P49841	GSK3B	S874	S868P	868	Missense	distal	-6	no	7.231	7.252	EPSD	ICGC	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	E9PAV3	NACA	P49841	GSK3B	S874	S874P	874	Missense	central	0	yes	7.231	0.000	EPSD	ICGC	6.007	Loss
CMGC_GSK_GSK3B_ST	E9PAV3	NACA	P49841	GSK3B	S874	P867S	867	Missense	distal	-7	no	7.231	7.233	EPSD	ICGC	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	E9PAV3	NACA	P49841	GSK3B	S874	S874F	874	Missense	central	0	yes	7.231	0.000	EPSD	ICGC;COSMIC	6.007	Loss
CMGC_GSK_GSK3B_ST	E9PAV3	NACA	P49841	GSK3B	T879	S874F	874	Missense	distal	-5	no	5.687	6.247	EPSD	ICGC;COSMIC	6.007	Gain
CMGC_GSK_GSK3B_ST	E9PAV3	NACA	P49841	GSK3B	S917	A923E	923	Missense	distal	6	no	7.255	7.251	EPSD	ICGC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	E9PAV3	NACA	P49841	GSK3B	S917	P918H	918	Missense	proximal	1	no	7.255	3.554	EPSD	ICGC;COSMIC	6.007	Loss
CMGC_GSK_GSK3B_ST	E9PAV3	NACA	P49841	GSK3B	S917	S917F	917	Missense	central	0	yes	7.255	0.000	EPSD	ICGC;COSMIC	6.007	Loss
CMGC_GSK_GSK3B_ST	E9PAV3	NACA	P49841	GSK3B	S933	G938W	938	Missense	distal	5	no	7.068	6.041	EPSD	ICGC;COSMIC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	E9PAV3	NACA	P49841	GSK3B	S933	P931L	931	Missense	proximal	-2	no	7.068	6.738	EPSD	ICGC;COSMIC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	E9PAV3	NACA	P49841	GSK3B	S933	P927L	927	Missense	distal	-6	no	7.068	7.046	EPSD	ICGC;COSMIC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	E9PAV3	NACA	P49841	GSK3B	S933	P927S	927	Missense	distal	-6	no	7.068	7.048	EPSD	ICGC;COSMIC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	E9PAV3	NACA	P49841	GSK3B	S935	P942T	942	Missense	distal	7	no	8.003	8.008	EPSD	ICGC;COSMIC	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	E9PAV3	NACA	P49841	GSK3B	S935	G938W	938	Missense	distal	3	no	8.003	7.848	EPSD	ICGC;COSMIC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	E9PAV3	NACA	P49841	GSK3B	S935	P931L	931	Missense	distal	-4	no	8.003	7.217	EPSD	ICGC;COSMIC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	E9PAV3	NACA	P49841	GSK3B	T941	P942T	942	Missense	proximal	1	no	6.638	3.447	EPSD	ICGC;COSMIC	6.007	Loss
CMGC_GSK_GSK3B_ST	E9PAV3	NACA	P49841	GSK3B	T941	G938W	938	Missense	distal	-3	no	6.638	6.741	EPSD	ICGC;COSMIC	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	E9PAV3	NACA	P49841	GSK3B	T946	P942T	942	Missense	distal	-4	no	6.385	6.613	EPSD	ICGC;COSMIC	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	E9PAV3	NACA	P49841	GSK3B	T946	G952E	952	Missense	distal	6	no	6.385	6.383	EPSD	ICGC;COSMIC;CCLE	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	E9PAV3	NACA	P49841	GSK3B	T946	S949F	949	Missense	distal	3	no	6.385	6.174	EPSD	ICGC;COSMIC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	E9PAV3	NACA	P49841	GSK3B	S949	P942T	942	Missense	distal	-7	no	6.462	6.491	EPSD	ICGC;COSMIC	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	E9PAV3	NACA	P49841	GSK3B	S949	G952E	952	Missense	distal	3	no	6.462	6.399	EPSD	ICGC;COSMIC;CCLE	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	E9PAV3	NACA	P49841	GSK3B	S949	S949F	949	Missense	central	0	yes	6.462	0.000	EPSD	ICGC;COSMIC	6.007	Loss
CMGC_GSK_GSK3B_ST	E9PAV3	NACA	P49841	GSK3B	T969	A962S	962	Missense	distal	-7	no	6.079	6.056	EPSD	ICGC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	E9PAV3	NACA	P49841	GSK3B	T987	P986L	986	Missense	proximal	-1	no	6.921	6.790	EPSD	ICGC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	E9PAV3	NACA	P49841	GSK3B	T992	P986L	986	Missense	distal	-6	no	6.254	6.232	EPSD	ICGC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	E9PAV3	NACA	P49841	GSK3B	T992	S995F	995	Missense	distal	3	no	6.254	6.043	EPSD	ICGC;COSMIC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	E9PAV3	NACA	P49841	GSK3B	S995	S995F	995	Missense	central	0	yes	6.854	0.000	EPSD	ICGC;COSMIC	6.007	Loss
CMGC_GSK_GSK3B_ST	E9PAV3	NACA	P49841	GSK3B	T1010	P1016H	1016	Missense	distal	6	no	6.850	6.838	EPSD	ICGC;COSMIC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	E9PAV3	NACA	P49841	GSK3B	T1015	P1016H	1016	Missense	proximal	1	no	6.160	2.459	EPSD	ICGC;COSMIC	6.007	Loss
CMGC_GSK_GSK3B_ST	E9PAV3	NACA	P49841	GSK3B	S1018	P1016H	1016	Missense	proximal	-2	no	10.603	10.241	EPSD	ICGC;COSMIC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	E9PAV3	NACA	P49841	GSK3B	S1022	P1016H	1016	Missense	distal	-6	no	8.912	8.857	EPSD	ICGC;COSMIC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	E9PAV3	NACA	P49841	GSK3B	S1022	P1029L	1029	Missense	distal	7	no	8.912	8.961	EPSD	ICGC	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	E9PAV3	NACA	P49841	GSK3B	S1022	F1028S	1028	Missense	distal	6	no	8.912	8.924	EPSD	ICGC;COSMIC	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	E9PAV3	NACA	P49841	GSK3B	S1042	G1045E	1045	Missense	distal	3	no	10.152	10.089	EPSD	ICGC;COSMIC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	E9PAV3	NACA	P49841	GSK3B	S1042	P1047S	1047	Missense	distal	5	no	10.152	9.198	EPSD	ICGC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	E9PAV3	NACA	P49841	GSK3B	S1042	P1043S	1043	Missense	proximal	1	no	10.152	6.307	EPSD	ICGC;COSMIC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	E9PAV3	NACA	P49841	GSK3B	S1046	G1045E	1045	Missense	proximal	-1	no	8.771	8.753	EPSD	ICGC;COSMIC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	E9PAV3	NACA	P49841	GSK3B	S1046	P1053S	1053	Missense	distal	7	no	8.771	8.835	EPSD	ICGC;CCLE	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	E9PAV3	NACA	P49841	GSK3B	S1046	P1047S	1047	Missense	proximal	1	no	8.771	4.926	EPSD	ICGC	6.007	Loss
CMGC_GSK_GSK3B_ST	E9PAV3	NACA	P49841	GSK3B	S1046	P1043S	1043	Missense	distal	-3	no	8.771	8.888	EPSD	ICGC;COSMIC	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	E9PAV3	NACA	P49841	GSK3B	T1050	G1045E	1045	Missense	distal	-5	no	6.914	6.879	EPSD	ICGC;COSMIC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	E9PAV3	NACA	P49841	GSK3B	T1050	P1053S	1053	Missense	distal	3	no	6.914	6.896	EPSD	ICGC;CCLE	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	E9PAV3	NACA	P49841	GSK3B	T1050	P1047S	1047	Missense	distal	-3	no	6.914	7.031	EPSD	ICGC	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	E9PAV3	NACA	P49841	GSK3B	T1050	P1043S	1043	Missense	distal	-7	no	6.914	6.916	EPSD	ICGC;COSMIC	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	E9PAV3	NACA	P49841	GSK3B	T1059	T1059P	1059	Missense	central	0	yes	7.536	0.000	EPSD	ICGC;COSMIC	6.007	Loss
CMGC_GSK_GSK3B_ST	E9PAV3	NACA	P49841	GSK3B	T1059	L1064P	1064	Missense	distal	5	no	7.536	8.817	EPSD	ICGC;COSMIC	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	E9PAV3	NACA	P49841	GSK3B	T1059	P1060L	1060	Missense	proximal	1	no	7.536	4.676	EPSD	ICGC	6.007	Loss
CMGC_GSK_GSK3B_ST	E9PAV3	NACA	P49841	GSK3B	T1059	P1053S	1053	Missense	distal	-6	no	7.536	7.515	EPSD	ICGC;CCLE	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	E9PAV3	NACA	P49841	GSK3B	T1059	P1065S	1065	Missense	distal	6	no	7.536	7.534	EPSD	ICGC;COSMIC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	E9PAV3	NACA	P49841	GSK3B	T1063	L1064P	1064	Missense	proximal	1	no	3.698	6.559	EPSD	ICGC;COSMIC	6.007	Gain
CMGC_GSK_GSK3B_ST	E9PAV3	NACA	P49841	GSK3B	S1066	P1067R	1067	Missense	proximal	1	no	6.153	3.833	EPSD	ICGC;COSMIC	6.007	Loss
CMGC_GSK_GSK3B_ST	E9PAV3	NACA	P49841	GSK3B	S1066	P1071L	1071	Missense	distal	5	no	6.153	4.873	EPSD	ICGC;COSMIC	6.007	Loss
CMGC_GSK_GSK3B_ST	E9PAV3	NACA	P49841	GSK3B	S1066	T1059P	1059	Missense	distal	-7	no	6.153	6.125	EPSD	ICGC;COSMIC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	E9PAV3	NACA	P49841	GSK3B	S1066	L1064P	1064	Missense	proximal	-2	no	6.153	6.484	EPSD	ICGC;COSMIC	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	E9PAV3	NACA	P49841	GSK3B	S1066	P1060L	1060	Missense	distal	-6	no	6.153	6.131	EPSD	ICGC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	E9PAV3	NACA	P49841	GSK3B	S1066	P1065S	1065	Missense	proximal	-1	no	6.153	6.097	EPSD	ICGC;COSMIC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	E9PAV3	NACA	P49841	GSK3B	T1081	P1088L	1088	Missense	distal	7	no	6.852	6.901	EPSD	ICGC;COSMIC	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	E9PAV3	NACA	P49841	GSK3B	T1081	L1076P	1076	Missense	distal	-5	no	6.852	6.586	EPSD	ICGC;COSMIC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	E9PAV3	NACA	P49841	GSK3B	T1081	A1085V	1085	Missense	distal	4	no	6.852	6.873	EPSD	ICGC;COSMIC	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	E9PAV3	NACA	P49841	GSK3B	T1086	P1090S	1090	Missense	distal	4	no	5.882	8.853	EPSD	ICGC;COSMIC	6.007	Gain
CMGC_GSK_GSK3B_ST	E9PAV3	NACA	P49841	GSK3B	T1086	A1085V	1085	Missense	proximal	-1	no	5.882	6.085	EPSD	ICGC;COSMIC	6.007	Gain
CMGC_GSK_GSK3B_ST	E9PAV3	NACA	P49841	GSK3B	S1089	P1088L	1088	Missense	proximal	-1	no	6.241	6.110	EPSD	ICGC;COSMIC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	E9PAV3	NACA	P49841	GSK3B	S1089	P1094S	1094	Missense	distal	5	no	6.241	5.287	EPSD	ICGC;COSMIC	6.007	Loss
CMGC_GSK_GSK3B_ST	E9PAV3	NACA	P49841	GSK3B	S1089	P1090S	1090	Missense	proximal	1	no	6.241	2.396	EPSD	ICGC;COSMIC	6.007	Loss
CMGC_GSK_GSK3B_ST	E9PAV3	NACA	P49841	GSK3B	S1089	G1093S	1093	Missense	distal	4	no	6.241	9.484	EPSD	ICGC;COSMIC	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	E9PAV3	NACA	P49841	GSK3B	S1089	A1085V	1085	Missense	distal	-4	no	6.241	6.167	EPSD	ICGC;COSMIC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	E9PAV3	NACA	P49841	GSK3B	T1096	S1098P	1098	Missense	proximal	2	no	5.685	6.129	EPSD	ICGC;COSMIC	6.007	Gain
CMGC_GSK_GSK3B_ST	E9PAV3	NACA	P49841	GSK3B	T1109	P1113L	1113	Missense	distal	4	no	6.082	6.335	EPSD	ICGC;COSMIC	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	E9PAV3	NACA	P49841	GSK3B	T1109	P1111L	1111	Missense	proximal	2	no	6.082	5.698	EPSD	ICGC;COSMIC;CCLE	6.007	Loss
CMGC_GSK_GSK3B_ST	E9PAV3	NACA	P49841	GSK3B	T1109	A1108V	1108	Missense	proximal	-1	no	6.082	6.285	EPSD	ICGC;COSMIC	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	E9PAV3	NACA	P49841	GSK3B	T1109	P1106L	1106	Missense	distal	-3	no	6.082	6.208	EPSD	ICGC	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	E9PAV3	NACA	P49841	GSK3B	T1109	M1104T	1104	Missense	distal	-5	no	6.082	6.069	EPSD	ICGC;COSMIC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	E9PAV3	NACA	P49841	GSK3B	T1119	H1122P	1122	Missense	distal	3	no	6.245	6.291	EPSD	ICGC;COSMIC	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	E9PAV3	NACA	P49841	GSK3B	T1119	H1122Q	1122	Missense	distal	3	no	6.245	6.235	EPSD	ICGC;COSMIC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	E9PAV3	NACA	P49841	GSK3B	T1119	P1113L	1113	Missense	distal	-6	no	6.245	6.222	EPSD	ICGC;COSMIC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	E9PAV3	NACA	P49841	GSK3B	T1127	T1128P	1128	Missense	proximal	1	no	3.583	6.774	EPSD	ICGC;COSMIC	6.007	Gain
CMGC_GSK_GSK3B_ST	E9PAV3	NACA	P49841	GSK3B	T1128	H1122P	1122	Missense	distal	-6	no	8.774	8.828	EPSD	ICGC;COSMIC	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	E9PAV3	NACA	P49841	GSK3B	T1128	P1129Q	1129	Missense	proximal	1	no	8.774	5.505	EPSD	ICGC;COSMIC	6.007	Loss
CMGC_GSK_GSK3B_ST	E9PAV3	NACA	P49841	GSK3B	T1128	H1122Q	1122	Missense	distal	-6	no	8.774	8.803	EPSD	ICGC;COSMIC	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	E9PAV3	NACA	P49841	GSK3B	T1128	P1134L	1134	Missense	distal	6	no	8.774	8.767	EPSD	ICGC;COSMIC;CCLE	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	E9PAV3	NACA	P49841	GSK3B	T1128	T1128P	1128	Missense	central	0	yes	8.774	0.000	EPSD	ICGC;COSMIC	6.007	Loss
CMGC_GSK_GSK3B_ST	E9PAV3	NACA	P49841	GSK3B	T1128	A1131V	1131	Missense	distal	3	no	8.774	8.903	EPSD	ICGC;COSMIC	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	E9PAV3	NACA	P49841	GSK3B	T1132	P1129Q	1129	Missense	distal	-3	no	6.326	6.473	EPSD	ICGC;COSMIC	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	E9PAV3	NACA	P49841	GSK3B	T1132	P1134L	1134	Missense	proximal	2	no	6.326	5.942	EPSD	ICGC;COSMIC;CCLE	6.007	Loss
CMGC_GSK_GSK3B_ST	E9PAV3	NACA	P49841	GSK3B	T1132	T1128P	1128	Missense	distal	-4	no	6.326	6.098	EPSD	ICGC;COSMIC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	E9PAV3	NACA	P49841	GSK3B	T1132	A1131V	1131	Missense	proximal	-1	no	6.326	6.529	EPSD	ICGC;COSMIC	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	E9PAV3	NACA	P49841	GSK3B	S1135	L1140P	1140	Missense	distal	5	no	4.911	6.191	EPSD	ICGC;COSMIC	6.007	Gain
CMGC_GSK_GSK3B_ST	E9PAV3	NACA	P49841	GSK3B	T1142	L1140P	1140	Missense	proximal	-2	no	6.386	6.717	EPSD	ICGC;COSMIC	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	E9PAV3	NACA	P49841	GSK3B	T1142	P1145L	1145	Missense	distal	3	no	6.386	6.068	EPSD	ICGC;COSMIC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	E9PAV3	NACA	P49841	GSK3B	T1142	A1148V	1148	Missense	distal	6	no	6.386	6.378	EPSD	ICGC;COSMIC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	E9PAV3	NACA	P49841	GSK3B	T1142	P1149L	1149	Missense	distal	7	no	6.386	6.435	EPSD	ICGC;COSMIC	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	E9PAV3	NACA	P49841	GSK3B	T1142	P1145S	1145	Missense	distal	3	no	6.386	6.368	EPSD	ICGC;COSMIC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	E9PAV3	NACA	P49841	GSK3B	T1151	P1145L	1145	Missense	distal	-6	no	8.872	8.850	EPSD	ICGC;COSMIC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	E9PAV3	NACA	P49841	GSK3B	T1151	S1158F	1158	Missense	distal	7	no	8.872	8.950	EPSD	ICGC	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	E9PAV3	NACA	P49841	GSK3B	T1151	A1148V	1148	Missense	distal	-3	no	8.872	9.019	EPSD	ICGC;COSMIC	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	E9PAV3	NACA	P49841	GSK3B	T1151	P1157L	1157	Missense	distal	6	no	8.872	8.865	EPSD	ICGC;COSMIC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	E9PAV3	NACA	P49841	GSK3B	T1151	P1149L	1149	Missense	proximal	-2	no	8.872	8.542	EPSD	ICGC;COSMIC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	E9PAV3	NACA	P49841	GSK3B	T1151	P1145S	1145	Missense	distal	-6	no	8.872	8.851	EPSD	ICGC;COSMIC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	E9PAV3	NACA	P49841	GSK3B	T1155	S1158F	1158	Missense	distal	3	no	6.403	6.192	EPSD	ICGC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	E9PAV3	NACA	P49841	GSK3B	T1155	A1148V	1148	Missense	distal	-7	no	6.403	6.402	EPSD	ICGC;COSMIC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	E9PAV3	NACA	P49841	GSK3B	T1155	P1157L	1157	Missense	proximal	2	no	6.403	6.019	EPSD	ICGC;COSMIC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	E9PAV3	NACA	P49841	GSK3B	T1155	P1149L	1149	Missense	distal	-6	no	6.403	6.381	EPSD	ICGC;COSMIC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	E9PAV3	NACA	P49841	GSK3B	T1165	G1170R	1170	Missense	distal	5	no	5.940	6.214	EPSD	ICGC	6.007	Gain
CMGC_GSK_GSK3B_ST	E9PAV3	NACA	P49841	GSK3B	T1173	T1174P	1174	Missense	proximal	1	no	3.197	6.388	EPSD	ICGC	6.007	Gain
CMGC_GSK_GSK3B_ST	E9PAV3	NACA	P49841	GSK3B	T1174	P1180L	1180	Missense	distal	6	no	8.864	8.857	EPSD	ICGC;COSMIC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	E9PAV3	NACA	P49841	GSK3B	T1174	G1170R	1170	Missense	distal	-4	no	8.864	8.105	EPSD	ICGC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	E9PAV3	NACA	P49841	GSK3B	T1174	T1174P	1174	Missense	central	0	yes	8.864	0.000	EPSD	ICGC	6.007	Loss
CMGC_GSK_GSK3B_ST	E9PAV3	NACA	P49841	GSK3B	T1174	P1175S	1175	Missense	proximal	1	no	8.864	5.019	EPSD	ICGC;COSMIC	6.007	Loss
CMGC_GSK_GSK3B_ST	E9PAV3	NACA	P49841	GSK3B	T1178	P1180L	1180	Missense	proximal	2	no	6.385	6.001	EPSD	ICGC;COSMIC	6.007	Loss
CMGC_GSK_GSK3B_ST	E9PAV3	NACA	P49841	GSK3B	T1178	T1174P	1174	Missense	distal	-4	no	6.385	6.158	EPSD	ICGC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	E9PAV3	NACA	P49841	GSK3B	T1178	P1182S	1182	Missense	distal	4	no	6.385	9.357	EPSD	ICGC;COSMIC	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	E9PAV3	NACA	P49841	GSK3B	T1178	P1175S	1175	Missense	distal	-3	no	6.385	6.502	EPSD	ICGC;COSMIC	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	E9PAV3	NACA	P49841	GSK3B	S1190	P1191S	1191	Missense	proximal	1	no	7.188	3.344	EPSD	ICGC;COSMIC	6.007	Loss
CMGC_GSK_GSK3B_ST	E9PAV3	NACA	P49841	GSK3B	S1190	P1191L	1191	Missense	proximal	1	no	7.188	4.328	EPSD	ICGC;COSMIC	6.007	Loss
CMGC_GSK_GSK3B_ST	E9PAV3	NACA	P49841	GSK3B	S1190	T1197P	1197	Missense	distal	7	no	7.188	7.184	EPSD	ICGC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	E9PAV3	NACA	P49841	GSK3B	S1190	S1190P	1190	Missense	central	0	yes	7.188	0.000	EPSD	ICGC;COSMIC	6.007	Loss
CMGC_GSK_GSK3B_ST	E9PAV3	NACA	P49841	GSK3B	T1196	T1197P	1197	Missense	proximal	1	no	3.176	6.367	EPSD	ICGC	6.007	Gain
CMGC_GSK_GSK3B_ST	E9PAV3	NACA	P49841	GSK3B	T1197	P1191S	1191	Missense	distal	-6	no	8.865	8.844	EPSD	ICGC;COSMIC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	E9PAV3	NACA	P49841	GSK3B	T1197	P1191L	1191	Missense	distal	-6	no	8.865	8.843	EPSD	ICGC;COSMIC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	E9PAV3	NACA	P49841	GSK3B	T1197	T1197P	1197	Missense	central	0	yes	8.865	0.000	EPSD	ICGC	6.007	Loss
CMGC_GSK_GSK3B_ST	E9PAV3	NACA	P49841	GSK3B	T1197	S1190P	1190	Missense	distal	-7	no	8.865	8.864	EPSD	ICGC;COSMIC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	E9PAV3	NACA	P49841	GSK3B	T1201	T1197P	1197	Missense	distal	-4	no	6.380	6.152	EPSD	ICGC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	E9PAV3	NACA	P49841	GSK3B	S1204	L1209P	1209	Missense	distal	5	no	5.156	6.436	EPSD	ICGC	6.007	Gain
CMGC_GSK_GSK3B_ST	E9PAV3	NACA	P49841	GSK3B	S1213	L1209P	1209	Missense	distal	-4	no	7.192	7.979	EPSD	ICGC	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	E9PAV3	NACA	P49841	GSK3B	S1213	T1220I	1220	Missense	distal	7	no	7.192	7.586	EPSD	ICGC	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	E9PAV3	NACA	P49841	GSK3B	S1213	T1220P	1220	Missense	distal	7	no	7.192	7.188	EPSD	ICGC;COSMIC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	E9PAV3	NACA	P49841	GSK3B	S1213	S1213P	1213	Missense	central	0	yes	7.192	0.000	EPSD	ICGC;COSMIC	6.007	Loss
CMGC_GSK_GSK3B_ST	E9PAV3	NACA	P49841	GSK3B	S1213	P1214S	1214	Missense	proximal	1	no	7.192	3.347	EPSD	ICGC;COSMIC	6.007	Loss
CMGC_GSK_GSK3B_ST	E9PAV3	NACA	P49841	GSK3B	S1213	T1211A	1211	Missense	proximal	-2	no	7.192	6.830	EPSD	ICGC;COSMIC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	E9PAV3	NACA	P49841	GSK3B	T1219	T1220P	1220	Missense	proximal	1	no	3.178	6.369	EPSD	ICGC;COSMIC	6.007	Gain
CMGC_GSK_GSK3B_ST	E9PAV3	NACA	P49841	GSK3B	T1220	T1220I	1220	Missense	central	0	yes	8.880	0.000	EPSD	ICGC	6.007	Loss
CMGC_GSK_GSK3B_ST	E9PAV3	NACA	P49841	GSK3B	T1220	T1220P	1220	Missense	central	0	yes	8.880	0.000	EPSD	ICGC;COSMIC	6.007	Loss
CMGC_GSK_GSK3B_ST	E9PAV3	NACA	P49841	GSK3B	T1220	S1213P	1213	Missense	distal	-7	no	8.880	8.879	EPSD	ICGC;COSMIC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	E9PAV3	NACA	P49841	GSK3B	T1220	P1214S	1214	Missense	distal	-6	no	8.880	8.859	EPSD	ICGC;COSMIC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	E9PAV3	NACA	P49841	GSK3B	T1220	S1227F	1227	Missense	distal	7	no	8.880	8.958	EPSD	ICGC;COSMIC	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	E9PAV3	NACA	P49841	GSK3B	T1224	T1220I	1220	Missense	distal	-4	no	6.380	4.233	EPSD	ICGC	6.007	Loss
CMGC_GSK_GSK3B_ST	E9PAV3	NACA	P49841	GSK3B	T1224	T1220P	1220	Missense	distal	-4	no	6.380	6.152	EPSD	ICGC;COSMIC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	E9PAV3	NACA	P49841	GSK3B	T1224	S1227F	1227	Missense	distal	3	no	6.380	6.169	EPSD	ICGC;COSMIC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	E9PAV3	NACA	P49841	GSK3B	T1234	S1236P	1236	Missense	proximal	2	no	5.716	6.160	EPSD	ICGC;COSMIC;CCLE	6.007	Gain
CMGC_GSK_GSK3B_ST	E9PAV3	NACA	P49841	GSK3B	S1236	P1237S	1237	Missense	proximal	1	no	7.257	3.412	EPSD	ICGC	6.007	Loss
CMGC_GSK_GSK3B_ST	E9PAV3	NACA	P49841	GSK3B	S1236	S1236P	1236	Missense	central	0	yes	7.257	0.000	EPSD	ICGC;COSMIC;CCLE	6.007	Loss
CMGC_GSK_GSK3B_ST	E9PAV3	NACA	P49841	GSK3B	T1243	A1246T	1246	Missense	distal	3	no	8.899	9.204	EPSD	ICGC;COSMIC	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	E9PAV3	NACA	P49841	GSK3B	T1243	P1237S	1237	Missense	distal	-6	no	8.899	8.878	EPSD	ICGC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	E9PAV3	NACA	P49841	GSK3B	T1243	S1236P	1236	Missense	distal	-7	no	8.899	8.898	EPSD	ICGC;COSMIC;CCLE	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	E9PAV3	NACA	P49841	GSK3B	T1243	P1244L	1244	Missense	proximal	1	no	8.899	6.039	EPSD	ICGC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	E9PAV3	NACA	P49841	GSK3B	T1247	A1246T	1246	Missense	proximal	-1	no	6.704	6.784	EPSD	ICGC;COSMIC	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	E9PAV3	NACA	P49841	GSK3B	T1247	P1244L	1244	Missense	distal	-3	no	6.704	6.830	EPSD	ICGC	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	E9PAV3	NACA	P49841	GSK3B	S1250	A1246T	1246	Missense	distal	-4	no	6.698	7.522	EPSD	ICGC;COSMIC	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	E9PAV3	NACA	P49841	GSK3B	S1250	P1244L	1244	Missense	distal	-6	no	6.698	6.676	EPSD	ICGC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	E9PAV3	NACA	P49841	GSK3B	T1257	P1260H	1260	Missense	distal	3	no	6.481	6.435	EPSD	ICGC;COSMIC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	E9PAV3	NACA	P49841	GSK3B	T1265	P1266T	1266	Missense	proximal	1	no	6.791	3.600	EPSD	ICGC;COSMIC	6.007	Loss
CMGC_GSK_GSK3B_ST	E9PAV3	NACA	P49841	GSK3B	T1265	P1260H	1260	Missense	distal	-5	no	6.791	7.114	EPSD	ICGC;COSMIC	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	E9PAV3	NACA	P49841	GSK3B	T1265	P1266L	1266	Missense	proximal	1	no	6.791	3.930	EPSD	ICGC;COSMIC	6.007	Loss
CMGC_GSK_GSK3B_ST	E9PAV3	NACA	P49841	GSK3B	T1265	P1267S	1267	Missense	proximal	2	no	6.791	6.347	EPSD	ICGC;COSMIC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	E9PAV3	NACA	P49841	GSK3B	T1280	A1279P	1279	Missense	proximal	-1	no	5.872	6.082	EPSD	ICGC;COSMIC	6.007	Gain
CMGC_GSK_GSK3B_ST	E9PAV3	NACA	P49841	GSK3B	T1293	P1287L	1287	Missense	distal	-6	no	6.518	6.496	EPSD	ICGC;COSMIC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	E9PAV3	NACA	P49841	GSK3B	T1293	G1299E	1299	Missense	distal	6	no	6.518	6.516	EPSD	ICGC;COSMIC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	E9PAV3	NACA	P49841	GSK3B	S1296	G1299E	1299	Missense	distal	3	no	6.395	6.332	EPSD	ICGC;COSMIC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	E9PAV3	NACA	P49841	GSK3B	S1296	T1303S	1303	Missense	distal	7	no	6.395	6.454	EPSD	ICGC;COSMIC	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	E9PAV3	NACA	P49841	GSK3B	S1304	S1304P	1304	Missense	central	0	yes	6.683	0.000	EPSD	ICGC;COSMIC	6.007	Loss
CMGC_GSK_GSK3B_ST	E9PAV3	NACA	P49841	GSK3B	S1304	P1305H	1305	Missense	proximal	1	no	6.683	2.982	EPSD	ICGC;COSMIC	6.007	Loss
CMGC_GSK_GSK3B_ST	E9PAV3	NACA	P49841	GSK3B	S1304	G1299E	1299	Missense	distal	-5	no	6.683	6.647	EPSD	ICGC;COSMIC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	E9PAV3	NACA	P49841	GSK3B	S1304	T1303S	1303	Missense	proximal	-1	no	6.683	6.758	EPSD	ICGC;COSMIC	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	E9PAV3	NACA	P49841	GSK3B	T1311	P1318T	1318	Missense	distal	7	no	6.691	6.695	EPSD	ICGC;COSMIC	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	E9PAV3	NACA	P49841	GSK3B	T1311	S1304P	1304	Missense	distal	-7	no	6.691	6.689	EPSD	ICGC;COSMIC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	E9PAV3	NACA	P49841	GSK3B	T1311	P1312S	1312	Missense	proximal	1	no	6.691	2.846	EPSD	ICGC;COSMIC	6.007	Loss
CMGC_GSK_GSK3B_ST	E9PAV3	NACA	P49841	GSK3B	T1311	P1305H	1305	Missense	distal	-6	no	6.691	6.636	EPSD	ICGC;COSMIC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	E9PAV3	NACA	P49841	GSK3B	T1316	P1318T	1318	Missense	proximal	2	no	6.283	5.966	EPSD	ICGC;COSMIC	6.007	Loss
CMGC_GSK_GSK3B_ST	E9PAV3	NACA	P49841	GSK3B	T1316	P1312S	1312	Missense	distal	-4	no	6.283	6.847	EPSD	ICGC;COSMIC	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	E9PAV3	NACA	P49841	GSK3B	S1319	G1325A	1325	Missense	distal	6	no	9.848	9.850	EPSD	ICGC;COSMIC	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	E9PAV3	NACA	P49841	GSK3B	S1319	P1318T	1318	Missense	proximal	-1	no	9.848	9.717	EPSD	ICGC;COSMIC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	E9PAV3	NACA	P49841	GSK3B	S1319	P1312S	1312	Missense	distal	-7	no	9.848	9.850	EPSD	ICGC;COSMIC	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	E9PAV3	NACA	P49841	GSK3B	S1319	P1324S	1324	Missense	distal	5	no	9.848	8.894	EPSD	ICGC;COSMIC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	E9PAV3	NACA	P49841	GSK3B	S1323	G1325A	1325	Missense	proximal	2	no	6.219	6.485	EPSD	ICGC;COSMIC	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	E9PAV3	NACA	P49841	GSK3B	S1323	P1318T	1318	Missense	distal	-5	no	6.219	6.665	EPSD	ICGC;COSMIC	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	E9PAV3	NACA	P49841	GSK3B	S1323	P1329L	1329	Missense	distal	6	no	6.219	6.212	EPSD	ICGC;COSMIC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	E9PAV3	NACA	P49841	GSK3B	S1323	P1324S	1324	Missense	proximal	1	no	6.219	2.374	EPSD	ICGC;COSMIC	6.007	Loss
CMGC_GSK_GSK3B_ST	E9PAV3	NACA	P49841	GSK3B	T1334	P1336S	1336	Missense	proximal	2	no	7.433	6.989	EPSD	ICGC;COSMIC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	E9PAV3	NACA	P49841	GSK3B	T1334	P1329L	1329	Missense	distal	-5	no	7.433	7.699	EPSD	ICGC;COSMIC	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	E9PAV3	NACA	P49841	GSK3B	T1334	P1335L	1335	Missense	proximal	1	no	7.433	4.573	EPSD	ICGC;COSMIC	6.007	Loss
CMGC_GSK_GSK3B_ST	E9PAV3	NACA	P49841	GSK3B	T1334	A1337V	1337	Missense	distal	3	no	7.433	7.562	EPSD	ICGC;COSMIC	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	E9PAV3	NACA	P49841	GSK3B	T1334	P1336A	1336	Missense	proximal	2	no	7.433	6.997	EPSD	ICGC;COSMIC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	E9PAV3	NACA	P49841	GSK3B	S1342	P1336S	1336	Missense	distal	-6	no	8.618	8.597	EPSD	ICGC;COSMIC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	E9PAV3	NACA	P49841	GSK3B	S1342	S1342F	1342	Missense	central	0	yes	8.618	0.000	EPSD	ICGC	6.007	Loss
CMGC_GSK_GSK3B_ST	E9PAV3	NACA	P49841	GSK3B	S1342	P1335L	1335	Missense	distal	-7	no	8.618	8.620	EPSD	ICGC;COSMIC	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	E9PAV3	NACA	P49841	GSK3B	S1342	A1337V	1337	Missense	distal	-5	no	8.618	8.920	EPSD	ICGC;COSMIC	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	E9PAV3	NACA	P49841	GSK3B	S1342	P1336A	1336	Missense	distal	-6	no	8.618	8.608	EPSD	ICGC;COSMIC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	E9PAV3	NACA	P49841	GSK3B	S1388	R1391I	1391	Missense	distal	3	no	7.402	7.352	EPSD	ICGC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	E9PAV3	NACA	P49841	GSK3B	S1397	S1404F	1404	Missense	distal	7	no	8.753	8.830	EPSD	ICGC;COSMIC	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	E9PAV3	NACA	P49841	GSK3B	S1397	D1401N	1401	Missense	distal	4	no	8.753	7.566	EPSD	ICGC;COSMIC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	E9PAV3	NACA	P49841	GSK3B	S1397	R1391I	1391	Missense	distal	-6	no	8.753	8.747	EPSD	ICGC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	E9PAV3	NACA	P49841	GSK3B	S1397	P1398L	1398	Missense	proximal	1	no	8.753	5.892	EPSD	ICGC;COSMIC	6.007	Loss
CMGC_GSK_GSK3B_ST	E9PAV3	NACA	P49841	GSK3B	S1404	S1404F	1404	Missense	central	0	yes	8.035	0.000	EPSD	ICGC;COSMIC	6.007	Loss
CMGC_GSK_GSK3B_ST	E9PAV3	NACA	P49841	GSK3B	S1404	D1401N	1401	Missense	distal	-3	no	8.035	7.894	EPSD	ICGC;COSMIC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	E9PAV3	NACA	P49841	GSK3B	S1404	P1398L	1398	Missense	distal	-6	no	8.035	8.012	EPSD	ICGC;COSMIC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	E9PAV3	NACA	P49841	GSK3B	S1411	S1404F	1404	Missense	distal	-7	no	7.716	7.726	EPSD	ICGC;COSMIC	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	E9PAV3	NACA	P49841	GSK3B	T1418	R1422K	1422	Missense	distal	4	no	6.127	5.963	EPSD	ICGC;COSMIC	6.007	Loss
CMGC_GSK_GSK3B_ST	E9PAV3	NACA	P49841	GSK3B	T1434	S1429C	1429	Missense	distal	-5	no	6.725	7.244	EPSD	ICGC;COSMIC	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	E9PAV3	NACA	P49841	GSK3B	T1434	P1435H	1435	Missense	proximal	1	no	6.725	3.024	EPSD	ICGC;COSMIC	6.007	Loss
CMGC_GSK_GSK3B_ST	E9PAV3	NACA	P49841	GSK3B	T1434	A1437E	1437	Missense	distal	3	no	6.725	7.042	EPSD	ICGC	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	E9PAV3	NACA	P49841	GSK3B	T1434	P1436Q	1436	Missense	proximal	2	no	6.725	6.503	EPSD	ICGC;COSMIC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	E9PAV3	NACA	P49841	GSK3B	T1434	P1436T	1436	Missense	proximal	2	no	6.725	6.407	EPSD	ICGC;COSMIC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	E9PAV3	NACA	P49841	GSK3B	S1474	P1473R	1473	Missense	proximal	-1	no	6.876	6.682	EPSD	ICGC;COSMIC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	E9PAV3	NACA	P49841	GSK3B	S1474	L1467I	1467	Missense	distal	-7	no	6.876	6.903	EPSD	ICGC;COSMIC	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	E9PAV3	NACA	P49841	GSK3B	S1474	P1478H	1478	Missense	distal	4	no	6.876	6.091	EPSD	ICGC;COSMIC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	E9PAV3	NACA	P49841	GSK3B	S1512	L1505V	1505	Missense	distal	-7	no	7.157	7.178	EPSD	ICGC;COSMIC	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	E9PAV3	NACA	P49841	GSK3B	S1512	V1516G	1516	Missense	distal	4	no	7.157	6.304	EPSD	ICGC;COSMIC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	E9PAV3	NACA	P49841	GSK3B	S1512	P1517A	1517	Missense	distal	5	no	7.157	6.128	EPSD	ICGC;COSMIC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	E9PAV3	NACA	P49841	GSK3B	S1512	P1513L	1513	Missense	proximal	1	no	7.157	4.296	EPSD	ICGC;COSMIC	6.007	Loss
CMGC_GSK_GSK3B_ST	E9PAV3	NACA	P49841	GSK3B	S1512	P1510H	1510	Missense	proximal	-2	no	7.157	6.795	EPSD	ICGC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	E9PAV3	NACA	P49841	GSK3B	T1519	V1516G	1516	Missense	distal	-3	no	6.113	5.942	EPSD	ICGC;COSMIC	6.007	Loss
CMGC_GSK_GSK3B_ST	E9PAV3	NACA	P49841	GSK3B	T1519	P1517A	1517	Missense	proximal	-2	no	6.113	5.522	EPSD	ICGC;COSMIC	6.007	Loss
CMGC_GSK_GSK3B_ST	E9PAV3	NACA	P49841	GSK3B	T1519	P1513L	1513	Missense	distal	-6	no	6.113	6.091	EPSD	ICGC;COSMIC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	E9PAV3	NACA	P49841	GSK3B	S1557	S1557P	1557	Missense	central	0	yes	8.657	0.000	EPSD	ICGC;COSMIC	6.007	Loss
CMGC_GSK_GSK3B_ST	E9PAV3	NACA	P49841	GSK3B	S1557	K1560N	1560	Missense	distal	3	no	8.657	8.832	EPSD	ICGC;COSMIC	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	E9PAV3	NACA	P49841	GSK3B	S1557	S1557F	1557	Missense	central	0	yes	8.657	0.000	EPSD	ICGC;COSMIC	6.007	Loss
CMGC_GSK_GSK3B_ST	E9PAV3	NACA	P49841	GSK3B	S1557	P1558R	1558	Missense	proximal	1	no	8.657	6.338	EPSD	ICGC;COSMIC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	E9PAV3	NACA	P49841	GSK3B	S1557	M1553V	1553	Missense	distal	-4	no	8.657	8.484	EPSD	ICGC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	E9PAV3	NACA	P49841	GSK3B	T1573	E1569G	1569	Missense	distal	-4	no	5.938	6.107	EPSD	ICGC;COSMIC	6.007	Gain
CMGC_GSK_GSK3B_ST	E9PAV3	NACA	P49841	GSK3B	S1581	P1574S	1574	Missense	distal	-7	no	6.073	6.074	EPSD	ICGC;COSMIC	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	E9PAV3	NACA	P49841	GSK3B	S1581	S1576F	1576	Missense	distal	-5	no	6.073	6.633	EPSD	ICGC;COSMIC	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	E9PAV3	NACA	P49841	GSK3B	S1607	E1612K	1612	Missense	distal	5	no	7.135	6.268	EPSD	ICGC;COSMIC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	E9PAV3	NACA	P49841	GSK3B	S1607	S1609Y	1609	Missense	proximal	2	no	7.135	6.903	EPSD	ICGC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	E9PAV3	NACA	P49841	GSK3B	S1609	E1612K	1612	Missense	distal	3	no	7.811	7.704	EPSD	ICGC;COSMIC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	E9PAV3	NACA	P49841	GSK3B	S1609	S1609Y	1609	Missense	central	0	yes	7.811	0.000	EPSD	ICGC	6.007	Loss
CMGC_GSK_GSK3B_ST	E9PAV3	NACA	P49841	GSK3B	T1615	E1612K	1612	Missense	distal	-3	no	6.387	6.397	EPSD	ICGC;COSMIC	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	E9PAV3	NACA	P49841	GSK3B	T1615	S1609Y	1609	Missense	distal	-6	no	6.387	6.300	EPSD	ICGC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	E9PAV3	NACA	P49841	GSK3B	T1620	G1627A	1627	Missense	distal	7	no	7.542	7.870	EPSD	ICGC	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	E9PAV3	NACA	P49841	GSK3B	S1623	G1627A	1627	Missense	distal	4	no	7.454	8.286	EPSD	ICGC	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	E9PAV3	NACA	P49841	GSK3B	T1630	G1627A	1627	Missense	distal	-3	no	6.927	6.951	EPSD	ICGC	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	E9PAV3	NACA	P49841	GSK3B	T1630	A1632D	1632	Missense	proximal	2	no	6.927	7.011	EPSD	ICGC	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	E9PAV3	NACA	P49841	GSK3B	T1630	P1637L	1637	Missense	distal	7	no	6.927	6.976	EPSD	ICGC	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	E9PAV3	NACA	P49841	GSK3B	T1636	P1640S	1640	Missense	distal	4	no	4.687	7.659	EPSD	ICGC	6.007	Gain
CMGC_GSK_GSK3B_ST	E9PAV3	NACA	P49841	GSK3B	S1639	A1632D	1632	Missense	distal	-7	no	10.191	10.172	EPSD	ICGC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	E9PAV3	NACA	P49841	GSK3B	S1639	P1640S	1640	Missense	proximal	1	no	10.191	6.346	EPSD	ICGC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	E9PAV3	NACA	P49841	GSK3B	S1639	P1637L	1637	Missense	proximal	-2	no	10.191	9.861	EPSD	ICGC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	E9PAV3	NACA	P49841	GSK3B	T1643	L1647I	1647	Missense	distal	4	no	7.640	7.036	EPSD	ICGC;COSMIC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	E9PAV3	NACA	P49841	GSK3B	T1643	P1640S	1640	Missense	distal	-3	no	7.640	7.757	EPSD	ICGC	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	E9PAV3	NACA	P49841	GSK3B	T1643	P1637L	1637	Missense	distal	-6	no	7.640	7.618	EPSD	ICGC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	E9PAV3	NACA	P49841	GSK3B	S1646	L1647I	1647	Missense	proximal	1	no	7.207	6.186	EPSD	ICGC;COSMIC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	E9PAV3	NACA	P49841	GSK3B	S1646	P1640S	1640	Missense	distal	-6	no	7.207	7.186	EPSD	ICGC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	E9PAV3	NACA	P49841	GSK3B	S1646	S1653F	1653	Missense	distal	7	no	7.207	7.285	EPSD	ICGC;COSMIC	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	E9PAV3	NACA	P49841	GSK3B	S1650	S1656F	1656	Missense	distal	6	no	6.568	6.555	EPSD	ICGC;COSMIC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	E9PAV3	NACA	P49841	GSK3B	S1650	L1647I	1647	Missense	distal	-3	no	6.568	6.671	EPSD	ICGC;COSMIC	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	E9PAV3	NACA	P49841	GSK3B	S1650	S1653F	1653	Missense	distal	3	no	6.568	6.357	EPSD	ICGC;COSMIC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	E9PAV3	NACA	P49841	GSK3B	T1652	L1647I	1647	Missense	distal	-5	no	5.671	6.035	EPSD	ICGC;COSMIC	6.007	Gain
CMGC_GSK_GSK3B_ST	E9PAV3	NACA	P49841	GSK3B	S1653	S1656F	1656	Missense	distal	3	no	7.095	6.884	EPSD	ICGC;COSMIC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	E9PAV3	NACA	P49841	GSK3B	S1653	L1647I	1647	Missense	distal	-6	no	7.095	7.033	EPSD	ICGC;COSMIC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	E9PAV3	NACA	P49841	GSK3B	S1653	S1653F	1653	Missense	central	0	yes	7.095	0.000	EPSD	ICGC;COSMIC	6.007	Loss
CMGC_GSK_GSK3B_ST	E9PAV3	NACA	P49841	GSK3B	S1709	S1710Y	1710	Missense	proximal	1	no	5.992	6.518	EPSD	ICGC	6.007	Gain
CMGC_GSK_GSK3B_ST	E9PAV3	NACA	P49841	GSK3B	S1709	I1716V	1716	Missense	distal	7	no	5.992	6.082	EPSD	ICGC;CCLE	6.007	Gain
CMGC_GSK_GSK3B_ST	E9PAV3	NACA	P49841	GSK3B	S1709	P1704L	1704	Missense	distal	-5	no	5.992	6.257	EPSD	ICGC;COSMIC	6.007	Gain
CMGC_GSK_GSK3B_ST	E9PAV3	NACA	P49841	GSK3B	S1799	P1794L	1794	Missense	distal	-5	no	5.903	6.168	EPSD	ICGC;COSMIC	6.007	Gain
CMGC_GSK_GSK3B_ST	E9PAV3	NACA	P49841	GSK3B	S1805	L1800V	1800	Missense	distal	-5	no	7.237	7.708	EPSD	ICGC;COSMIC	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	E9PAV3	NACA	P49841	GSK3B	S1805	S1799Y	1799	Missense	distal	-6	no	7.237	7.151	EPSD	ICGC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	E9PAV3	NACA	P49841	GSK3B	S1805	P1811S	1811	Missense	distal	6	no	7.237	7.235	EPSD	ICGC;COSMIC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	Q92837	FRAT1	P49841	GSK3B	S179	S179P	179	Missense	central	0	yes	6.132	0.000	EPSD	ICGC;COSMIC	6.007	Loss
CMGC_GSK_GSK3B_ST	Q92837	FRAT1	P49841	GSK3B	S188	Q189L	189	Missense	proximal	1	no	6.852	7.260	PhosphoSitePlus	ICGC;COSMIC	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	Q92837	FRAT1	P49841	GSK3B	S188	T194A	194	Missense	distal	6	no	6.852	6.848	PhosphoSitePlus	ICGC;COSMIC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	Q92837	FRAT1	P49841	GSK3B	S249	S252R	252	Missense	distal	3	no	7.700	7.330	EPSD	ICGC;COSMIC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	Q92837	FRAT1	P49841	GSK3B	S249	A255S	255	Missense	distal	6	no	7.700	7.702	EPSD	ICGC	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	Q92837	FRAT1	P49841	GSK3B	S249	R251G	251	Missense	proximal	2	no	7.700	7.424	EPSD	ICGC;COSMIC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	Q92837	FRAT1	P49841	GSK3B	S249	P250T	250	Missense	proximal	1	no	7.700	4.509	EPSD	ICGC;COSMIC	6.007	Loss
CAMK_MAPKAPK_MK2_MAPKAPK3_ST	Q8N5C8	TAB3	Q16644	MAPKAPK3	S82	S83T	83	Missense	proximal	1	no	0.013	0.014	EPSD	ICGC;COSMIC	0.011	Up-regulation
CAMK_MAPKAPK_MK2_MAPKAPK3_ST	Q8N5C8	TAB3	Q16644	MAPKAPK3	S102	L98M	98	Missense	distal	-4	no	0.011	0.010	EPSD	ICGC	0.011	Loss
CAMK_MAPKAPK_MK2_MAPKAPK3_ST	Q8N5C8	TAB3	Q16644	MAPKAPK3	S103	S103G	103	Missense	central	0	yes	0.014	0.000	EPSD	ICGC	0.011	Loss
CAMK_MAPKAPK_MK2_MAPKAPK3_ST	Q8N5C8	TAB3	Q16644	MAPKAPK3	S103	L98M	98	Missense	distal	-5	no	0.014	0.012	EPSD	ICGC	0.011	Down-regulation
CAMK_MAPKAPK_MK2_MAPKAPK3_ST	Q8N5C8	TAB3	Q16644	MAPKAPK3	S385	R382M	382	Missense	distal	-3	no	0.029	0.015	EPSD	ICGC;COSMIC	0.011	Down-regulation
CAMK_MAPKAPK_MK2_MAPKAPK3_ST	Q8N5C8	TAB3	Q16644	MAPKAPK3	S415	P418T	418	Missense	distal	3	no	0.023	0.022	EPSD	ICGC	0.011	Down-regulation
CAMK_MAPKAPK_MK2_MAPKAPK3_ST	Q8N5C8	TAB3	Q16644	MAPKAPK3	S444	P449T	449	Missense	distal	5	no	0.011	0.010	EPSD	ICGC	0.011	Loss
CAMK_MAPKAPK_MK2_MAPKAPK3_ST	Q8N5C8	TAB3	Q16644	MAPKAPK3	S506	R503K	503	Missense	distal	-3	no	0.029	0.015	PhosphoSitePlus	ICGC;COSMIC	0.011	Down-regulation
CAMK_MAPKAPK_MK2_MAPKAPK3_ST	Q8N5C8	TAB3	Q16644	MAPKAPK3	S669	T670K	670	Missense	proximal	1	no	0.021	0.020	EPSD	ICGC;COSMIC	0.011	Down-regulation
CAMK_MAPKAPK_MK2_MAPKAPK3_ST	Q14457	BECN1	Q16644	MAPKAPK3	S90	P85Q	85	Missense	distal	-5	no	0.026	0.025	PhosphoSitePlus	ICGC	0.011	Down-regulation
CAMK_MAPKAPK_MK2_MAPKAPK3_ST	Q14457	BECN1	Q16644	MAPKAPK3	S113	S113R	113	Missense	central	0	yes	0.013	0.000	EPSD	ICGC	0.011	Loss
CAMK_MAPKAPK_MK2_MAPKAPK3_ST	Q14457	BECN1	Q16644	MAPKAPK3	S337	G334R	334	Missense	distal	-3	no	0.006	0.021	EPSD	ICGC;COSMIC	0.011	Gain
TK_Tec_BMX_Y	Q05397	PTK2	P51813	BMX	Y194	A187T	187	Missense	distal	-7	no	5.195	4.998	EPSD;PhosphoSitePlus	ICGC;COSMIC	2.549	Down-regulation
TK_Tec_BMX_Y	Q05397	PTK2	P51813	BMX	Y441	D435N	435	Missense	distal	-6	no	5.381	5.367	EPSD;PhosphoSitePlus	ICGC;COSMIC	2.549	Down-regulation
TK_Tec_BMX_Y	Q05397	PTK2	P51813	BMX	Y441	H437N	437	Missense	distal	-4	no	5.381	5.457	EPSD;PhosphoSitePlus	ICGC	2.549	Up-regulation
TK_Tec_BMX_Y	Q05397	PTK2	P51813	BMX	Y861	P854L	854	Missense	distal	-7	no	4.819	4.918	EPSD;PhosphoSitePlus	ICGC;COSMIC	2.549	Up-regulation
TK_Tec_BMX_Y	Q05397	PTK2	P51813	BMX	Y861	H859Y	859	Missense	proximal	-2	no	4.819	4.321	EPSD;PhosphoSitePlus	ICGC;COSMIC	2.549	Down-regulation
TK_Tec_BMX_Y	Q05397	PTK2	P51813	BMX	Y898	S897Y	897	Missense	proximal	-1	no	4.895	4.911	EPSD;PhosphoSitePlus	ICGC	2.549	Up-regulation
TK_Tec_BMX_Y	Q05397	PTK2	P51813	BMX	Y898	S897N	897	Missense	proximal	-1	no	4.895	4.893	EPSD;PhosphoSitePlus	ICGC;COSMIC	2.549	Down-regulation
TK_Tec_BMX_Y	Q05397	PTK2	P51813	BMX	Y898	S897C	897	Missense	proximal	-1	no	4.895	4.926	EPSD;PhosphoSitePlus	ICGC	2.549	Up-regulation
TK_Tec_BMX_Y	Q07912	TNK2	P51813	BMX	Y284	D282N	282	Missense	proximal	-2	no	2.441	2.856	EPSD	ICGC;COSMIC	2.549	Gain
TK_Tec_BMX_Y	Q07912	TNK2	P51813	BMX	Y859	K852N	852	Missense	distal	-7	no	4.766	4.742	EPSD;PhosphoSitePlus	ICGC;COSMIC	2.549	Down-regulation
TK_Tec_BMX_Y	Q07912	TNK2	P51813	BMX	Y859	E864K	864	Missense	distal	5	no	4.766	4.870	EPSD;PhosphoSitePlus	ICGC;COSMIC	2.549	Up-regulation
TK_Tec_BMX_Y	Q07912	TNK2	P51813	BMX	Y859	S856R	856	Missense	distal	-3	no	4.766	4.752	EPSD;PhosphoSitePlus	ICGC	2.549	Down-regulation
TK_Tec_BMX_Y	Q07912	TNK2	P51813	BMX	Y860	E864K	864	Missense	distal	4	no	4.769	4.553	PhosphoSitePlus;EPSD	ICGC;COSMIC	2.549	Down-regulation
TK_Tec_BMX_Y	Q07912	TNK2	P51813	BMX	Y860	S856R	856	Missense	distal	-4	no	4.769	4.618	PhosphoSitePlus;EPSD	ICGC	2.549	Down-regulation
TK_Tec_BMX_Y	P56945	BCAR1	P51813	BMX	Y12	P19T	19	Missense	distal	7	no	3.444	3.394	PhosphoSitePlus	ICGC;COSMIC	2.549	Down-regulation
TK_Tec_BMX_Y	Q16611	BAK1	P51813	BMX	Y108	F111S	111	Missense	distal	3	no	4.703	5.076	PhosphoSitePlus	ICGC;COSMIC	2.549	Up-regulation
TK_Tec_BMX_Y	P08581	MET	P51813	BMX	Y1234	Y1230H	1230	Missense	distal	-4	no	2.603	3.268	EPSD	ICGC;COSMIC	2.549	Up-regulation
TK_Tec_BMX_Y	P08581	MET	P51813	BMX	Y1234	Y1230C	1230	Missense	distal	-4	no	2.603	2.349	EPSD	ICGC;COSMIC	2.549	Loss
TK_Tec_BMX_Y	P08581	MET	P51813	BMX	Y1234	D1228H	1228	Missense	distal	-6	no	2.603	2.617	EPSD	ICGC;COSMIC	2.549	Up-regulation
TK_Tec_BMX_Y	P08581	MET	P51813	BMX	Y1234	S1236R	1236	Missense	proximal	2	no	2.603	2.655	EPSD	ICGC;COSMIC	2.549	Up-regulation
TK_Tec_BMX_Y	P08581	MET	P51813	BMX	Y1234	H1238L	1238	Missense	distal	4	no	2.603	2.462	EPSD	ICGC;COSMIC	2.549	Loss
TK_Tec_BMX_Y	P08581	MET	P51813	BMX	Y1234	Y1235H	1235	Missense	proximal	1	no	2.603	2.616	EPSD	ICGC;COSMIC	2.549	Up-regulation
TK_Tec_BMX_Y	P08581	MET	P51813	BMX	Y1234	D1228Y	1228	Missense	distal	-6	no	2.603	2.612	EPSD	ICGC	2.549	Up-regulation
TK_Tec_BMX_Y	P08581	MET	P51813	BMX	Y1234	D1228A	1228	Missense	distal	-6	no	2.603	2.526	EPSD	ICGC	2.549	Loss
TK_Tec_BMX_Y	P08581	MET	P51813	BMX	Y1235	Y1230H	1230	Missense	distal	-5	no	4.805	4.840	PhosphoSitePlus	ICGC;COSMIC	2.549	Up-regulation
TK_Tec_BMX_Y	P08581	MET	P51813	BMX	Y1235	Y1230C	1230	Missense	distal	-5	no	4.805	4.652	PhosphoSitePlus	ICGC;COSMIC	2.549	Down-regulation
TK_Tec_BMX_Y	P08581	MET	P51813	BMX	Y1235	D1228H	1228	Missense	distal	-7	no	4.805	4.888	PhosphoSitePlus	ICGC;COSMIC	2.549	Up-regulation
TK_Tec_BMX_Y	P08581	MET	P51813	BMX	Y1235	S1236R	1236	Missense	proximal	1	no	4.805	4.882	PhosphoSitePlus	ICGC;COSMIC	2.549	Up-regulation
TK_Tec_BMX_Y	P08581	MET	P51813	BMX	Y1235	G1242V	1242	Missense	distal	7	no	4.805	4.822	PhosphoSitePlus	ICGC	2.549	Up-regulation
TK_Tec_BMX_Y	P08581	MET	P51813	BMX	Y1235	H1238L	1238	Missense	distal	3	no	4.805	4.923	PhosphoSitePlus	ICGC;COSMIC	2.549	Up-regulation
TK_Tec_BMX_Y	P08581	MET	P51813	BMX	Y1235	Y1235H	1235	Missense	central	0	yes	4.805	0.000	PhosphoSitePlus	ICGC;COSMIC	2.549	Loss
TK_Tec_BMX_Y	P08581	MET	P51813	BMX	Y1235	D1228Y	1228	Missense	distal	-7	no	4.805	4.772	PhosphoSitePlus	ICGC	2.549	Down-regulation
TK_Tec_BMX_Y	P08581	MET	P51813	BMX	Y1235	D1228A	1228	Missense	distal	-7	no	4.805	4.850	PhosphoSitePlus	ICGC	2.549	Up-regulation
Other_PLK_PLK2_PLK2_ST	Q9HC77	CENPJ	Q9NYY3	PLK2	S131	F133L	133	Missense	proximal	2	no	14.944	14.941	EPSD	ICGC;COSMIC	13.807	Down-regulation
Other_PLK_PLK2_PLK2_ST	Q9HC77	CENPJ	Q9NYY3	PLK2	S131	A130V	130	Missense	proximal	-1	no	14.944	14.934	EPSD	ICGC;COSMIC	13.807	Down-regulation
Other_PLK_PLK2_PLK2_ST	Q9HC77	CENPJ	Q9NYY3	PLK2	S131	P127T	127	Missense	distal	-4	no	14.944	15.098	EPSD	ICGC	13.807	Up-regulation
Other_PLK_PLK2_PLK2_ST	Q9HC77	CENPJ	Q9NYY3	PLK2	S131	D128Y	128	Missense	distal	-3	no	14.944	12.159	EPSD	ICGC	13.807	Loss
Other_PLK_PLK2_PLK2_ST	Q9HC77	CENPJ	Q9NYY3	PLK2	S131	E132K	132	Missense	proximal	1	no	14.944	15.400	EPSD	ICGC;COSMIC	13.807	Up-regulation
Other_PLK_PLK2_PLK2_ST	Q9HC77	CENPJ	Q9NYY3	PLK2	S471	P470L	470	Missense	proximal	-1	no	15.349	15.443	EPSD	ICGC	13.807	Up-regulation
Other_PLK_PLK2_PLK2_ST	Q9HC77	CENPJ	Q9NYY3	PLK2	S471	T477M	477	Missense	distal	6	no	15.349	13.050	EPSD	ICGC;COSMIC	13.807	Loss
Other_PLK_PLK2_PLK2_ST	Q9HC77	CENPJ	Q9NYY3	PLK2	S589	Q583E	583	Missense	distal	-6	no	21.223	21.820	PhosphoSitePlus;EPSD	ICGC	13.807	Up-regulation
Other_PLK_PLK2_PLK2_ST	Q9HC77	CENPJ	Q9NYY3	PLK2	T616	P617F	617	Missense	proximal	1	no	12.755	15.609	EPSD	ICGC	13.807	Gain
Other_PLK_PLK2_PLK2_ST	Q9HC77	CENPJ	Q9NYY3	PLK2	S663	Q657K	657	Missense	distal	-6	no	14.657	15.470	EPSD	ICGC	13.807	Up-regulation
Other_PLK_PLK2_PLK2_ST	Q9HC77	CENPJ	Q9NYY3	PLK2	S683	T687I	687	Missense	distal	4	no	14.691	16.397	EPSD	ICGC;COSMIC	13.807	Up-regulation
Other_PLK_PLK2_PLK2_ST	Q9HC77	CENPJ	Q9NYY3	PLK2	S787	S781L	781	Missense	distal	-6	no	15.002	14.457	EPSD	ICGC;COSMIC;CCLE	13.807	Down-regulation
Other_PLK_PLK2_PLK2_ST	Q9HC77	CENPJ	Q9NYY3	PLK2	S787	P780L	780	Missense	distal	-7	no	15.002	15.891	EPSD	ICGC;COSMIC	13.807	Up-regulation
Other_PLK_PLK2_PLK2_ST	O15350	TP73	Q9NYY3	PLK2	S48	G43D	43	Missense	distal	-5	no	17.945	18.630	PhosphoSitePlus	ICGC	13.807	Up-regulation
Other_PLK_PLK2_PLK2_ST	O15350	TP73	Q9NYY3	PLK2	S48	S48I	48	Missense	central	0	yes	17.945	0.000	PhosphoSitePlus	ICGC;COSMIC	13.807	Loss
Other_PLK_PLK2_PLK2_ST	O15350	TP73	Q9NYY3	PLK2	S48	G44R	44	Missense	distal	-4	no	17.945	18.753	PhosphoSitePlus	ICGC;COSMIC;GDSC;CCLE	13.807	Up-regulation
Other_PLK_PLK2_PLK2_ST	O15350	TP73	Q9NYY3	PLK2	S471	S471R	471	Missense	central	0	yes	15.653	0.000	EPSD	ICGC;COSMIC	13.807	Loss
Other_PLK_PLK2_PLK2_ST	O15350	TP73	Q9NYY3	PLK2	S471	S474F	474	Missense	distal	3	no	15.653	14.873	EPSD	ICGC	13.807	Down-regulation
Other_PLK_PLK2_PLK2_ST	P62258	YWHAE	Q9NYY3	PLK2	S59	S64R	64	Missense	distal	5	no	13.765	13.942	EPSD	ICGC	13.807	Gain
Other_PLK_PLK2_PLK2_ST	P62258	YWHAE	Q9NYY3	PLK2	S148	L149V	149	Missense	proximal	1	no	15.332	16.855	EPSD	ICGC	13.807	Up-regulation
Other_PLK_PLK2_PLK2_ST	P62258	YWHAE	Q9NYY3	PLK2	T208	L206R	206	Missense	proximal	-2	no	18.895	18.466	PhosphoSitePlus	ICGC;COSMIC	13.807	Down-regulation
Other_PLK_PLK2_PLK2_ST	P06748	NPM1	Q9NYY3	PLK2	S82	S88F	88	Missense	distal	6	no	16.603	14.034	EPSD	ICGC;COSMIC	13.807	Down-regulation
Other_PLK_PLK2_PLK2_ST	P06748	NPM1	Q9NYY3	PLK2	S106	V99F	99	Missense	distal	-7	no	15.403	16.344	EPSD	ICGC	13.807	Up-regulation
Other_PLK_PLK2_PLK2_ST	P06748	NPM1	Q9NYY3	PLK2	S106	V99L	99	Missense	distal	-7	no	15.403	16.859	EPSD	ICGC;COSMIC	13.807	Up-regulation
Other_PLK_PLK2_PLK2_ST	P06748	NPM1	Q9NYY3	PLK2	S106	L102F	102	Missense	distal	-4	no	15.403	15.800	EPSD	ICGC;COSMIC	13.807	Up-regulation
Other_PLK_PLK2_PLK2_ST	P06748	NPM1	Q9NYY3	PLK2	S106	S112I	112	Missense	distal	6	no	15.403	11.284	EPSD	ICGC	13.807	Loss
Other_PLK_PLK2_PLK2_ST	P06748	NPM1	Q9NYY3	PLK2	S106	V99A	99	Missense	distal	-7	no	15.403	15.722	EPSD	ICGC;COSMIC	13.807	Up-regulation
Other_PLK_PLK2_PLK2_ST	P06748	NPM1	Q9NYY3	PLK2	S195	R197G	197	Missense	proximal	2	no	15.008	14.710	EPSD	ICGC;COSMIC	13.807	Down-regulation
Other_PLK_PLK2_PLK2_ST	P06748	NPM1	Q9NYY3	PLK2	S195	P200A	200	Missense	distal	5	no	15.008	15.199	EPSD	ICGC	13.807	Up-regulation
Other_PLK_PLK2_PLK2_ST	P06748	NPM1	Q9NYY3	PLK2	S260	K263R	263	Missense	distal	3	no	14.641	13.567	EPSD	ICGC;COSMIC	13.807	Loss
Other_PLK_PLK2_PLK2_ST	P06748	NPM1	Q9NYY3	PLK2	S260	S254I	254	Missense	distal	-6	no	14.641	14.088	EPSD	ICGC	13.807	Down-regulation
Other_PLK_PLK2_PLK2_ST	Q969H0	FBXW7	Q9NYY3	PLK2	S25	R20I	20	Missense	distal	-5	no	15.261	14.276	EPSD;PhosphoSitePlus	ICGC;COSMIC	13.807	Down-regulation
Other_PLK_PLK2_PLK2_ST	Q969H0	FBXW7	Q9NYY3	PLK2	S25	P23S	23	Missense	proximal	-2	no	15.261	14.454	EPSD;PhosphoSitePlus	ICGC;COSMIC	13.807	Down-regulation
Other_PLK_PLK2_PLK2_ST	Q969H0	FBXW7	Q9NYY3	PLK2	S176	G175D	175	Missense	proximal	-1	no	20.125	19.991	PhosphoSitePlus;EPSD	ICGC;COSMIC	13.807	Down-regulation
Other_PLK_PLK2_PLK2_ST	Q969H0	FBXW7	Q9NYY3	PLK2	S176	S182F	182	Missense	distal	6	no	20.125	17.556	PhosphoSitePlus;EPSD	ICGC;COSMIC	13.807	Down-regulation
Other_PLK_PLK2_PLK2_ST	Q16143	SNCB	Q9NYY3	PLK2	S118	P123H	123	Missense	distal	5	no	13.950	14.111	PhosphoSitePlus	ICGC;COSMIC	13.807	Up-regulation
Other_PLK_PLK2_PLK2_ST	P53350	PLK1	Q9NYY3	PLK2	S137	E140Q	140	Missense	distal	3	no	23.568	25.674	PhosphoSitePlus	ICGC;COSMIC	13.807	Up-regulation
Other_PLK_PLK2_PLK2_ST	P53350	PLK1	Q9NYY3	PLK2	T366	H373Y	373	Missense	distal	7	no	17.311	15.980	EPSD	ICGC	13.807	Down-regulation
Other_PLK_PLK2_PLK2_ST	P53350	PLK1	Q9NYY3	PLK2	T366	T366K	366	Missense	central	0	yes	17.311	0.000	EPSD	ICGC;COSMIC	13.807	Loss
Other_PLK_PLK2_PLK2_ST	P53350	PLK1	Q9NYY3	PLK2	S578	R584S	584	Missense	distal	6	no	14.998	19.780	EPSD	ICGC;COSMIC	13.807	Up-regulation
Other_PLK_PLK2_PLK2_ST	P53350	PLK1	Q9NYY3	PLK2	S578	R584C	584	Missense	distal	6	no	14.998	17.893	EPSD	ICGC	13.807	Up-regulation
Other_PLK_PLK2_PLK2_ST	P37840	SNCA	Q9NYY3	PLK2	S129	Q134K	134	Missense	distal	5	no	17.753	17.669	PhosphoSitePlus	ICGC;COSMIC	13.807	Down-regulation
TKL_RAF_RAF_ARAF_ST	Q92934	BAD	P10398	ARAF	S75	R72S	72	Missense	distal	-3	no	6.566	5.252	PhosphoSitePlus;EPSD	ICGC	2.916	Down-regulation
TKL_RAF_RAF_ARAF_ST	Q92934	BAD	P10398	ARAF	S75	T80K	80	Missense	distal	5	no	6.566	6.634	PhosphoSitePlus;EPSD	ICGC	2.916	Up-regulation
TKL_RAF_RAF_ARAF_ST	Q92934	BAD	P10398	ARAF	S75	S74G	74	Missense	proximal	-1	no	6.566	6.739	PhosphoSitePlus;EPSD	ICGC;COSMIC	2.916	Up-regulation
TKL_RAF_RAF_ARAF_ST	Q92934	BAD	P10398	ARAF	S99	S99L	99	Missense	central	0	yes	6.419	0.000	EPSD;PhosphoSitePlus	ICGC	2.916	Loss
TKL_RAF_RAF_ARAF_ST	Q92934	BAD	P10398	ARAF	S99	R94W	94	Missense	distal	-5	no	6.419	6.306	EPSD;PhosphoSitePlus	ICGC	2.916	Down-regulation
TKL_RAF_RAF_ARAF_ST	Q92934	BAD	P10398	ARAF	S118	R112S	112	Missense	distal	-6	no	6.098	6.087	EPSD;PhosphoSitePlus	ICGC	2.916	Down-regulation
TKL_RAF_RAF_ARAF_ST	Q15599	SLC9A3R2	P10398	ARAF	S261	A263S	263	Missense	proximal	2	no	3.333	3.399	EPSD	ICGC	2.916	Up-regulation
TKL_RAF_RAF_ARAF_ST	Q02750	MAP2K1	P10398	ARAF	S218	G225C	225	Missense	distal	7	no	6.728	6.703	EPSD;PhosphoSitePlus	ICGC	2.916	Down-regulation
TKL_RAF_RAF_ARAF_ST	Q02750	MAP2K1	P10398	ARAF	S218	L215I	215	Missense	distal	-3	no	6.728	5.444	EPSD;PhosphoSitePlus	ICGC;COSMIC	2.916	Down-regulation
TKL_RAF_RAF_ARAF_ST	Q02750	MAP2K1	P10398	ARAF	S222	G225C	225	Missense	distal	3	no	6.846	6.849	PhosphoSitePlus;EPSD	ICGC	2.916	Up-regulation
TKL_RAF_RAF_ARAF_ST	Q02750	MAP2K1	P10398	ARAF	S222	L215I	215	Missense	distal	-7	no	6.846	6.761	PhosphoSitePlus;EPSD	ICGC;COSMIC	2.916	Down-regulation
CMGC_DYRK_DYRK1_DYRK1B_ST	Q02363	ID2	Q9Y463	DYRK1B	S5	R8S	8	Missense	distal	3	no	0.068	0.067	EPSD	ICGC;COSMIC	0.062	Down-regulation
CMGC_DYRK_DYRK1_DYRK1B_ST	Q02363	ID2	Q9Y463	DYRK1B	S5	R11M	11	Missense	distal	6	no	0.068	0.069	EPSD	ICGC;COSMIC	0.062	Up-regulation
CMGC_DYRK_DYRK1_DYRK1B_ST	Q02363	ID2	Q9Y463	DYRK1B	T27	P28L	28	Missense	proximal	1	no	0.122	0.055	PhosphoSitePlus	ICGC	0.062	Loss
CMGC_DYRK_DYRK1_DYRK1B_ST	Q9Y463	DYRK1B	Q9Y463	DYRK1B	T41	K47N	47	Missense	distal	6	no	0.066	0.067	EPSD	ICGC;COSMIC	0.062	Up-regulation
CMGC_DYRK_DYRK1_DYRK1B_ST	Q9Y463	DYRK1B	Q9Y463	DYRK1B	T41	P44L	44	Missense	distal	3	no	0.066	0.070	EPSD	ICGC;COSMIC	0.062	Up-regulation
CMGC_DYRK_DYRK1_DYRK1B_ST	Q9Y463	DYRK1B	Q9Y463	DYRK1B	T41	P44Q	44	Missense	distal	3	no	0.066	0.064	EPSD	ICGC;COSMIC	0.062	Down-regulation
CMGC_DYRK_DYRK1_DYRK1B_ST	Q9Y463	DYRK1B	Q9Y463	DYRK1B	T41	R38L	38	Missense	distal	-3	no	0.066	0.041	EPSD	ICGC;COSMIC	0.062	Loss
CMGC_DYRK_DYRK1_DYRK1B_ST	Q9Y463	DYRK1B	Q9Y463	DYRK1B	S49	L48F	48	Missense	proximal	-1	no	0.082	0.081	EPSD	ICGC;COSMIC	0.062	Down-regulation
CMGC_DYRK_DYRK1_DYRK1B_ST	Q9Y463	DYRK1B	Q9Y463	DYRK1B	S49	K47N	47	Missense	proximal	-2	no	0.082	0.077	EPSD	ICGC;COSMIC	0.062	Down-regulation
CMGC_DYRK_DYRK1_DYRK1B_ST	Q9Y463	DYRK1B	Q9Y463	DYRK1B	S49	P44L	44	Missense	distal	-5	no	0.082	0.085	EPSD	ICGC;COSMIC	0.062	Up-regulation
CMGC_DYRK_DYRK1_DYRK1B_ST	Q9Y463	DYRK1B	Q9Y463	DYRK1B	S49	P44Q	44	Missense	distal	-5	no	0.082	0.086	EPSD	ICGC;COSMIC	0.062	Up-regulation
CMGC_DYRK_DYRK1_DYRK1B_ST	Q9Y463	DYRK1B	Q9Y463	DYRK1B	S554	P559L	559	Missense	distal	5	no	0.101	0.103	EPSD	ICGC;COSMIC	0.062	Up-regulation
CMGC_DYRK_DYRK1_DYRK1B_ST	P24385	CCND1	Q9Y463	DYRK1B	T286	D289N	289	Missense	distal	3	no	0.074	0.068	EPSD	ICGC;COSMIC	0.062	Down-regulation
CMGC_DYRK_DYRK1_DYRK1B_ST	P24385	CCND1	Q9Y463	DYRK1B	T286	E280D	280	Missense	distal	-6	no	0.074	0.075	EPSD	ICGC	0.062	Up-regulation
CMGC_DYRK_DYRK1_DYRK1B_ST	P24385	CCND1	Q9Y463	DYRK1B	T286	P287A	287	Missense	proximal	1	no	0.074	0.020	EPSD	ICGC;COSMIC;GDSC;CCLE	0.062	Loss
CMGC_DYRK_DYRK1_DYRK1B_ST	P24385	CCND1	Q9Y463	DYRK1B	T288	D289N	289	Missense	proximal	1	no	0.077	0.058	PhosphoSitePlus	ICGC;COSMIC	0.062	Loss
CMGC_DYRK_DYRK1_DYRK1B_ST	P24385	CCND1	Q9Y463	DYRK1B	T288	P287A	287	Missense	proximal	-1	no	0.077	0.079	PhosphoSitePlus	ICGC;COSMIC;GDSC;CCLE	0.062	Up-regulation
CMGC_DYRK_DYRK1_DYRK1B_ST	P38936	CDKN1A	Q9Y463	DYRK1B	T57	D52N	52	Missense	distal	-5	no	0.101	0.104	EPSD	ICGC;COSMIC	0.062	Up-regulation
CMGC_DYRK_DYRK1_DYRK1B_ST	P38936	CDKN1A	Q9Y463	DYRK1B	T57	E56D	56	Missense	proximal	-1	no	0.101	0.098	EPSD	ICGC	0.062	Down-regulation
CMGC_DYRK_DYRK1_DYRK1B_ST	P38936	CDKN1A	Q9Y463	DYRK1B	T57	F51V	51	Missense	distal	-6	no	0.101	0.100	EPSD	ICGC;COSMIC	0.062	Down-regulation
CMGC_DYRK_DYRK1_DYRK1B_ST	P38936	CDKN1A	Q9Y463	DYRK1B	S130	P131T	131	Missense	proximal	1	no	0.073	0.030	EPSD	ICGC;COSMIC	0.062	Loss
CMGC_DYRK_DYRK1_DYRK1B_ST	P38936	CDKN1A	Q9Y463	DYRK1B	S130	P131Q	131	Missense	proximal	1	no	0.073	0.042	EPSD	ICGC;COSMIC	0.062	Loss
CMGC_DYRK_DYRK1_DYRK1B_ST	P38936	CDKN1A	Q9Y463	DYRK1B	S130	G129W	129	Missense	proximal	-1	no	0.073	0.072	EPSD	ICGC;COSMIC	0.062	Down-regulation
CMGC_DYRK_DYRK1_DYRK1B_ST	P20823	HNF1A	Q9Y463	DYRK1B	T74	E73D	73	Missense	proximal	-1	no	0.066	0.064	EPSD	ICGC	0.062	Down-regulation
CMGC_DYRK_DYRK1_DYRK1B_ST	P20823	HNF1A	Q9Y463	DYRK1B	T82	E88D	88	Missense	distal	6	no	0.107	0.108	EPSD	ICGC;COSMIC	0.062	Up-regulation
CMGC_DYRK_DYRK1_DYRK1B_ST	P20823	HNF1A	Q9Y463	DYRK1B	S93	E88D	88	Missense	distal	-5	no	0.078	0.075	EPSD	ICGC;COSMIC	0.062	Down-regulation
CMGC_DYRK_DYRK1_DYRK1B_ST	P20823	HNF1A	Q9Y463	DYRK1B	S249	I242F	242	Missense	distal	-7	no	0.096	0.097	PhosphoSitePlus	ICGC;COSMIC	0.062	Up-regulation
CMGC_DYRK_DYRK1_DYRK1B_ST	P20823	HNF1A	Q9Y463	DYRK1B	S304	P305L	305	Missense	proximal	1	no	0.065	-0.002	EPSD	ICGC	0.062	Loss
CMGC_DYRK_DYRK1_DYRK1B_ST	O75533	SF3B1	Q9Y463	DYRK1B	S129	I127T	127	Missense	proximal	-2	no	0.090	0.094	EPSD	ICGC	0.062	Up-regulation
CMGC_DYRK_DYRK1_DYRK1B_ST	O75533	SF3B1	Q9Y463	DYRK1B	S129	M126I	126	Missense	distal	-3	no	0.090	0.085	EPSD	ICGC;COSMIC	0.062	Down-regulation
CMGC_DYRK_DYRK1_DYRK1B_ST	O75533	SF3B1	Q9Y463	DYRK1B	S129	R132C	132	Missense	distal	3	no	0.090	0.089	EPSD	ICGC;COSMIC	0.062	Down-regulation
CMGC_DYRK_DYRK1_DYRK1B_ST	O75533	SF3B1	Q9Y463	DYRK1B	T207	P212L	212	Missense	distal	5	no	0.086	0.089	EPSD	ICGC;COSMIC	0.062	Up-regulation
CMGC_DYRK_DYRK1_DYRK1B_ST	O75533	SF3B1	Q9Y463	DYRK1B	T261	P262L	262	Missense	proximal	1	no	0.077	0.010	EPSD	ICGC;COSMIC	0.062	Loss
CMGC_DYRK_DYRK1_DYRK1B_ST	O75533	SF3B1	Q9Y463	DYRK1B	T273	D272H	272	Missense	proximal	-1	no	0.063	0.065	EPSD	ICGC;COSMIC	0.062	Up-regulation
CMGC_DYRK_DYRK1_DYRK1B_ST	O75533	SF3B1	Q9Y463	DYRK1B	S344	G347S	347	Missense	distal	3	no	0.071	0.064	EPSD	ICGC;COSMIC	0.062	Down-regulation
CMGC_DYRK_DYRK1_DYRK1B_ST	O75533	SF3B1	Q9Y463	DYRK1B	S344	P342T	342	Missense	proximal	-2	no	0.071	0.070	EPSD	ICGC;COSMIC	0.062	Down-regulation
CMGC_DYRK_DYRK1_DYRK1B_ST	O75533	SF3B1	Q9Y463	DYRK1B	S344	P351T	351	Missense	distal	7	no	0.071	0.070	EPSD	ICGC;COSMIC	0.062	Down-regulation
CMGC_DYRK_DYRK1_DYRK1B_ST	O75533	SF3B1	Q9Y463	DYRK1B	T350	G347S	347	Missense	distal	-3	no	0.054	0.071	EPSD	ICGC;COSMIC	0.062	Gain
CMGC_DYRK_DYRK1_DYRK1B_ST	O75533	SF3B1	Q9Y463	DYRK1B	T354	P351T	351	Missense	distal	-3	no	0.051	0.067	EPSD	ICGC;COSMIC	0.062	Gain
CMGC_DYRK_DYRK1_DYRK1B_ST	O75533	SF3B1	Q9Y463	DYRK1B	T369	H374Q	374	Missense	distal	5	no	0.065	0.062	EPSD	ICGC	0.062	Down-regulation
CMGC_DYRK_DYRK1_DYRK1B_ST	O75533	SF3B1	Q9Y463	DYRK1B	T369	A364D	364	Missense	distal	-5	no	0.065	0.062	EPSD	ICGC	0.062	Down-regulation
CMGC_DYRK_DYRK1_DYRK1B_ST	O75533	SF3B1	Q9Y463	DYRK1B	T369	T369I	369	Missense	central	0	yes	0.065	0.000	EPSD	ICGC	0.062	Loss
CMGC_DYRK_DYRK1_DYRK1B_ST	O75533	SF3B1	Q9Y463	DYRK1B	T434	P427Q	427	Missense	distal	-7	no	0.109	0.108	PhosphoSitePlus	ICGC	0.062	Down-regulation
CMGC_DYRK_DYRK1_DYRK1B_ST	O75533	SF3B1	Q9Y463	DYRK1B	T434	G439C	439	Missense	distal	5	no	0.109	0.101	PhosphoSitePlus	ICGC;COSMIC	0.062	Down-regulation
CMGC_DYRK_DYRK1_DYRK1B_ST	O75533	SF3B1	Q9Y463	DYRK1B	T508	P510Q	510	Missense	proximal	2	no	0.103	0.104	EPSD	ICGC;COSMIC	0.062	Up-regulation
CMGC_DYRK_DYRK1_DYRK1B_ST	O75533	SF3B1	Q9Y463	DYRK1B	S611	A604D	604	Missense	distal	-7	no	0.077	0.076	EPSD	ICGC	0.062	Down-regulation
CMGC_DYRK_DYRK1_DYRK1B_ST	O75533	SF3B1	Q9Y463	DYRK1B	S611	M609I	609	Missense	proximal	-2	no	0.077	0.076	EPSD	ICGC;COSMIC	0.062	Down-regulation
CMGC_DYRK_DYRK1_DYRK1B_ST	O75533	SF3B1	Q9Y463	DYRK1B	T1080	T1077K	1077	Missense	distal	-3	no	0.048	0.066	EPSD	ICGC	0.062	Gain
CMGC_DYRK_DYRK1_DYRK1B_ST	O75533	SF3B1	Q9Y463	DYRK1B	T1170	Y1167H	1167	Missense	distal	-3	no	0.073	0.076	EPSD	ICGC	0.062	Up-regulation
CAMK_MAPKAPK_MNK_MKNK2_ST	P23246	SFPQ	Q9HBH9	MKNK2	S8	R3G	3	Missense	distal	-5	no	26.618	26.830	EPSD;PhosphoSitePlus	ICGC	18.660	Up-regulation
CAMK_MAPKAPK_MNK_MKNK2_ST	P23246	SFPQ	Q9HBH9	MKNK2	S8	R3L	3	Missense	distal	-5	no	26.618	26.457	EPSD;PhosphoSitePlus	ICGC;COSMIC	18.660	Down-regulation
CAMK_MAPKAPK_MNK_MKNK2_ST	P23246	SFPQ	Q9HBH9	MKNK2	S8	G13D	13	Missense	distal	5	no	26.618	23.787	EPSD;PhosphoSitePlus	ICGC;COSMIC	18.660	Down-regulation
CAMK_MAPKAPK_MNK_MKNK2_ST	P23246	SFPQ	Q9HBH9	MKNK2	S33	P34S	34	Missense	proximal	1	no	17.561	20.236	EPSD	ICGC;COSMIC	18.660	Gain
CAMK_MAPKAPK_MNK_MKNK2_ST	P23246	SFPQ	Q9HBH9	MKNK2	S275	L282S	282	Missense	distal	7	no	18.191	18.724	EPSD	ICGC	18.660	Gain
CAMK_MAPKAPK_MNK_MKNK2_ST	P23246	SFPQ	Q9HBH9	MKNK2	S283	S283F	283	Missense	central	0	yes	32.280	0.000	PhosphoSitePlus;EPSD	ICGC;COSMIC	18.660	Loss
CAMK_MAPKAPK_MNK_MKNK2_ST	P23246	SFPQ	Q9HBH9	MKNK2	S283	L282S	282	Missense	proximal	-1	no	32.280	32.682	PhosphoSitePlus;EPSD	ICGC	18.660	Up-regulation
CAMK_MAPKAPK_MNK_MKNK2_ST	P23246	SFPQ	Q9HBH9	MKNK2	S379	N377S	377	Missense	proximal	-2	no	20.561	22.323	EPSD	ICGC;COSMIC	18.660	Up-regulation
CAMK_MAPKAPK_MNK_MKNK2_ST	P23246	SFPQ	Q9HBH9	MKNK2	S379	N384T	384	Missense	distal	5	no	20.561	20.426	EPSD	ICGC;COSMIC	18.660	Down-regulation
CAMK_MAPKAPK_MNK_MKNK2_ST	O43597	SPRY2	Q9HBH9	MKNK2	S97	R104L	104	Missense	distal	7	no	18.667	18.286	EPSD	ICGC;COSMIC	18.660	Loss
CAMK_MAPKAPK_MNK_MKNK2_ST	O43597	SPRY2	Q9HBH9	MKNK2	S112	R119Q	119	Missense	distal	7	no	31.862	31.788	PhosphoSitePlus;EPSD	ICGC;COSMIC	18.660	Down-regulation
CAMK_MAPKAPK_MNK_MKNK2_ST	O43597	SPRY2	Q9HBH9	MKNK2	S112	P106S	106	Missense	distal	-6	no	31.862	31.868	PhosphoSitePlus;EPSD	ICGC;COSMIC	18.660	Up-regulation
CAMK_MAPKAPK_MNK_MKNK2_ST	O43597	SPRY2	Q9HBH9	MKNK2	S120	R119Q	119	Missense	proximal	-1	no	21.544	21.475	EPSD	ICGC;COSMIC	18.660	Down-regulation
CAMK_MAPKAPK_MNK_MKNK2_ST	O43597	SPRY2	Q9HBH9	MKNK2	S120	T122M	122	Missense	proximal	2	no	21.544	21.947	EPSD	ICGC;COSMIC	18.660	Up-regulation
CAMK_MAPKAPK_MNK_MKNK2_ST	O43597	SPRY2	Q9HBH9	MKNK2	S121	R119Q	119	Missense	proximal	-2	no	31.478	30.591	EPSD;PhosphoSitePlus	ICGC;COSMIC	18.660	Down-regulation
CAMK_MAPKAPK_MNK_MKNK2_ST	O43597	SPRY2	Q9HBH9	MKNK2	S121	T122M	122	Missense	proximal	1	no	31.478	29.515	EPSD;PhosphoSitePlus	ICGC;COSMIC	18.660	Down-regulation
CAMK_MAPKAPK_MNK_MKNK2_ST	O43597	SPRY2	Q9HBH9	MKNK2	T122	R119Q	119	Missense	distal	-3	no	21.489	20.872	EPSD	ICGC;COSMIC	18.660	Down-regulation
CAMK_MAPKAPK_MNK_MKNK2_ST	O43597	SPRY2	Q9HBH9	MKNK2	T122	T122M	122	Missense	central	0	yes	21.489	0.000	EPSD	ICGC;COSMIC	18.660	Loss
CAMK_MAPKAPK_MNK_MKNK2_ST	O43597	SPRY2	Q9HBH9	MKNK2	T124	R119Q	119	Missense	distal	-5	no	19.649	19.583	EPSD	ICGC;COSMIC	18.660	Down-regulation
CAMK_MAPKAPK_MNK_MKNK2_ST	O43597	SPRY2	Q9HBH9	MKNK2	T124	T122M	122	Missense	proximal	-2	no	19.649	18.779	EPSD	ICGC;COSMIC	18.660	Down-regulation
CAMK_MAPKAPK_MNK_MKNK2_ST	P06730	EIF4E	Q9HBH9	MKNK2	S209	R214K	214	Missense	distal	5	no	32.281	32.746	PhosphoSitePlus	ICGC;COSMIC	18.660	Up-regulation
CAMK_PIM_PIM3_ST	Q92934	BAD	Q86V86	PIM3	S34	G35D	35	Missense	proximal	1	no	4.013	4.132	EPSD	ICGC;COSMIC	3.716	Up-regulation
CAMK_PIM_PIM3_ST	Q92934	BAD	Q86V86	PIM3	S57	H61N	61	Missense	distal	4	no	4.226	4.455	EPSD	ICGC	3.716	Up-regulation
CAMK_PIM_PIM3_ST	Q92934	BAD	Q86V86	PIM3	S75	R72S	72	Missense	distal	-3	no	9.418	8.195	PhosphoSitePlus	ICGC	3.716	Down-regulation
CAMK_PIM_PIM3_ST	Q92934	BAD	Q86V86	PIM3	S75	T80K	80	Missense	distal	5	no	9.418	9.315	PhosphoSitePlus	ICGC	3.716	Down-regulation
CAMK_PIM_PIM3_ST	Q92934	BAD	Q86V86	PIM3	S75	S74G	74	Missense	proximal	-1	no	9.418	9.617	PhosphoSitePlus	ICGC;COSMIC	3.716	Up-regulation
CAMK_PIM_PIM3_ST	Q92934	BAD	Q86V86	PIM3	S99	S99L	99	Missense	central	0	yes	4.680	0.000	EPSD	ICGC	3.716	Loss
CAMK_PIM_PIM3_ST	Q92934	BAD	Q86V86	PIM3	S99	R94W	94	Missense	distal	-5	no	4.680	3.240	EPSD	ICGC	3.716	Loss
CAMK_PIM_PIM3_ST	Q92934	BAD	Q86V86	PIM3	S145	R149L	149	Missense	distal	4	no	4.030	4.972	EPSD	ICGC;COSMIC	3.716	Up-regulation
CAMK_PIM_PIM3_ST	Q92934	BAD	Q86V86	PIM3	T148	R149L	149	Missense	proximal	1	no	3.864	4.011	EPSD	ICGC;COSMIC	3.716	Up-regulation
CAMK_PIM_PIM3_ST	P35568	IRS1	Q86V86	PIM3	S270	R265H	265	Missense	distal	-5	no	4.559	3.354	EPSD	ICGC	3.716	Loss
CAMK_PIM_PIM3_ST	P35568	IRS1	Q86V86	PIM3	S270	F264L	264	Missense	distal	-6	no	4.559	4.343	EPSD	ICGC	3.716	Down-regulation
CAMK_PIM_PIM3_ST	P35568	IRS1	Q86V86	PIM3	S270	S272P	272	Missense	proximal	2	no	4.559	4.576	EPSD	ICGC	3.716	Up-regulation
CAMK_PIM_PIM3_ST	P35568	IRS1	Q86V86	PIM3	S270	S268I	268	Missense	proximal	-2	no	4.559	4.705	EPSD	ICGC;COSMIC	3.716	Up-regulation
CAMK_PIM_PIM3_ST	P35568	IRS1	Q86V86	PIM3	S272	R265H	265	Missense	distal	-7	no	3.286	3.837	EPSD	ICGC	3.716	Gain
CAMK_PIM_PIM3_ST	P35568	IRS1	Q86V86	PIM3	T305	T300P	300	Missense	distal	-5	no	4.386	3.887	EPSD	ICGC;COSMIC;GDSC	3.716	Down-regulation
CAMK_PIM_PIM3_ST	P35568	IRS1	Q86V86	PIM3	S307	T300P	300	Missense	distal	-7	no	4.171	4.767	EPSD	ICGC;COSMIC;GDSC	3.716	Up-regulation
CAMK_PIM_PIM3_ST	P35568	IRS1	Q86V86	PIM3	S330	G332S	332	Missense	proximal	2	no	4.493	4.376	EPSD	ICGC;COSMIC	3.716	Down-regulation
CAMK_PIM_PIM3_ST	P35568	IRS1	Q86V86	PIM3	T335	G332S	332	Missense	distal	-3	no	4.036	4.492	EPSD	ICGC;COSMIC	3.716	Up-regulation
CAMK_PIM_PIM3_ST	P35568	IRS1	Q86V86	PIM3	S341	S345N	345	Missense	distal	4	no	4.644	4.631	EPSD	ICGC	3.716	Down-regulation
CAMK_PIM_PIM3_ST	P35568	IRS1	Q86V86	PIM3	S348	H355Q	355	Missense	distal	7	no	4.321	4.283	EPSD	ICGC	3.716	Down-regulation
CAMK_PIM_PIM3_ST	P35568	IRS1	Q86V86	PIM3	S348	S345N	345	Missense	distal	-3	no	4.321	3.086	EPSD	ICGC	3.716	Loss
CAMK_PIM_PIM3_ST	P35568	IRS1	Q86V86	PIM3	T397	S402C	402	Missense	distal	5	no	4.342	4.360	EPSD	ICGC;COSMIC	3.716	Up-regulation
CAMK_PIM_PIM3_ST	P35568	IRS1	Q86V86	PIM3	T397	S393T	393	Missense	distal	-4	no	4.342	3.996	EPSD	ICGC;COSMIC	3.716	Down-regulation
CAMK_PIM_PIM3_ST	P35568	IRS1	Q86V86	PIM3	T397	S396G	396	Missense	proximal	-1	no	4.342	4.541	EPSD	ICGC;CCLE	3.716	Up-regulation
CAMK_PIM_PIM3_ST	P35568	IRS1	Q86V86	PIM3	S398	S402C	402	Missense	distal	4	no	4.113	3.898	EPSD	ICGC;COSMIC	3.716	Down-regulation
CAMK_PIM_PIM3_ST	P35568	IRS1	Q86V86	PIM3	S398	S393T	393	Missense	distal	-5	no	4.113	4.343	EPSD	ICGC;COSMIC	3.716	Up-regulation
CAMK_PIM_PIM3_ST	P35568	IRS1	Q86V86	PIM3	S398	S396G	396	Missense	proximal	-2	no	4.113	4.424	EPSD	ICGC;CCLE	3.716	Up-regulation
CAMK_PIM_PIM3_ST	P35568	IRS1	Q86V86	PIM3	T403	S402C	402	Missense	proximal	-1	no	4.250	4.292	EPSD	ICGC;COSMIC	3.716	Up-regulation
CAMK_PIM_PIM3_ST	P35568	IRS1	Q86V86	PIM3	T403	S396G	396	Missense	distal	-7	no	4.250	4.504	EPSD	ICGC;CCLE	3.716	Up-regulation
CAMK_PIM_PIM3_ST	P35568	IRS1	Q86V86	PIM3	T403	R410W	410	Missense	distal	7	no	4.250	3.858	EPSD	ICGC	3.716	Down-regulation
CAMK_PIM_PIM3_ST	P35568	IRS1	Q86V86	PIM3	S415	S412P	412	Missense	distal	-3	no	4.182	2.884	EPSD	ICGC	3.716	Loss
CAMK_PIM_PIM3_ST	P35568	IRS1	Q86V86	PIM3	S415	S421R	421	Missense	distal	6	no	4.182	4.126	EPSD	ICGC	3.716	Down-regulation
CAMK_PIM_PIM3_ST	P35568	IRS1	Q86V86	PIM3	S415	A414D	414	Missense	proximal	-1	no	4.182	4.144	EPSD	ICGC	3.716	Down-regulation
CAMK_PIM_PIM3_ST	P35568	IRS1	Q86V86	PIM3	S415	R411L	411	Missense	distal	-4	no	4.182	5.244	EPSD	ICGC;COSMIC	3.716	Up-regulation
CAMK_PIM_PIM3_ST	P35568	IRS1	Q86V86	PIM3	S415	R410W	410	Missense	distal	-5	no	4.182	2.743	EPSD	ICGC	3.716	Loss
CAMK_PIM_PIM3_ST	P35568	IRS1	Q86V86	PIM3	S433	D437Y	437	Missense	distal	4	no	3.861	3.553	EPSD	ICGC;COSMIC	3.716	Loss
CAMK_PIM_PIM3_ST	P35568	IRS1	Q86V86	PIM3	T525	S531Y	531	Missense	distal	6	no	4.253	4.146	EPSD	ICGC	3.716	Down-regulation
CAMK_PIM_PIM3_ST	P35568	IRS1	Q86V86	PIM3	S527	S531Y	531	Missense	distal	4	no	3.958	3.440	EPSD	ICGC	3.716	Loss
CAMK_PIM_PIM3_ST	P35568	IRS1	Q86V86	PIM3	T579	R572M	572	Missense	distal	-7	no	4.333	4.891	EPSD	ICGC;COSMIC	3.716	Up-regulation
CAMK_PIM_PIM3_ST	P35568	IRS1	Q86V86	PIM3	T579	P578H	578	Missense	proximal	-1	no	4.333	4.335	EPSD	ICGC	3.716	Up-regulation
CAMK_PIM_PIM3_ST	P35568	IRS1	Q86V86	PIM3	T579	A575T	575	Missense	distal	-4	no	4.333	3.906	EPSD	ICGC;COSMIC	3.716	Down-regulation
CAMK_PIM_PIM3_ST	P35568	IRS1	Q86V86	PIM3	S603	R600H	600	Missense	distal	-3	no	4.669	3.180	EPSD	ICGC;COSMIC	3.716	Loss
CAMK_PIM_PIM3_ST	P35568	IRS1	Q86V86	PIM3	S636	Y632C	632	Missense	distal	-4	no	3.533	3.842	EPSD	ICGC;COSMIC	3.716	Gain
CAMK_PIM_PIM3_ST	P35568	IRS1	Q86V86	PIM3	T793	T793A	793	Missense	central	0	yes	4.369	0.000	EPSD	ICGC;COSMIC	3.716	Loss
CAMK_PIM_PIM3_ST	P35568	IRS1	Q86V86	PIM3	T793	Y800C	800	Missense	distal	7	no	4.369	4.359	EPSD	ICGC;COSMIC	3.716	Down-regulation
CAMK_PIM_PIM3_ST	P35568	IRS1	Q86V86	PIM3	T793	R790H	790	Missense	distal	-3	no	4.369	2.880	EPSD	ICGC	3.716	Loss
CAMK_PIM_PIM3_ST	P35568	IRS1	Q86V86	PIM3	S794	T793A	793	Missense	proximal	-1	no	4.487	4.380	EPSD	ICGC;COSMIC	3.716	Down-regulation
CAMK_PIM_PIM3_ST	P35568	IRS1	Q86V86	PIM3	S794	Y800C	800	Missense	distal	6	no	4.487	4.352	EPSD	ICGC;COSMIC	3.716	Down-regulation
CAMK_PIM_PIM3_ST	P35568	IRS1	Q86V86	PIM3	S794	T793S	793	Missense	proximal	-1	no	4.487	4.237	EPSD	ICGC;COSMIC	3.716	Down-regulation
CAMK_PIM_PIM3_ST	P35568	IRS1	Q86V86	PIM3	S794	R790H	790	Missense	distal	-4	no	4.487	4.933	EPSD	ICGC	3.716	Up-regulation
CAMK_PIM_PIM3_ST	P35568	IRS1	Q86V86	PIM3	S795	T793A	793	Missense	proximal	-2	no	4.451	4.392	EPSD	ICGC;COSMIC	3.716	Down-regulation
CAMK_PIM_PIM3_ST	P35568	IRS1	Q86V86	PIM3	S795	Y800C	800	Missense	distal	5	no	4.451	4.376	EPSD	ICGC;COSMIC	3.716	Down-regulation
CAMK_PIM_PIM3_ST	P35568	IRS1	Q86V86	PIM3	S795	T793S	793	Missense	proximal	-2	no	4.451	4.279	EPSD	ICGC;COSMIC	3.716	Down-regulation
CAMK_PIM_PIM3_ST	P35568	IRS1	Q86V86	PIM3	S795	R790H	790	Missense	distal	-5	no	4.451	3.245	EPSD	ICGC	3.716	Loss
CAMK_PIM_PIM3_ST	P35568	IRS1	Q86V86	PIM3	T859	P866T	866	Missense	distal	7	no	4.638	4.673	EPSD	ICGC	3.716	Up-regulation
CAMK_PIM_PIM3_ST	P35568	IRS1	Q86V86	PIM3	T870	K867T	867	Missense	distal	-3	no	4.657	4.767	EPSD	ICGC	3.716	Up-regulation
CAMK_PIM_PIM3_ST	P35568	IRS1	Q86V86	PIM3	T870	R873P	873	Missense	distal	3	no	4.657	5.081	EPSD	ICGC	3.716	Up-regulation
CAMK_PIM_PIM3_ST	P35568	IRS1	Q86V86	PIM3	T870	P866T	866	Missense	distal	-4	no	4.657	4.300	EPSD	ICGC	3.716	Down-regulation
CAMK_PIM_PIM3_ST	P35568	IRS1	Q86V86	PIM3	T870	A874G	874	Missense	distal	4	no	4.657	4.559	EPSD	ICGC;COSMIC	3.716	Down-regulation
CAMK_PIM_PIM3_ST	P35568	IRS1	Q86V86	PIM3	S1101	S1106L	1106	Missense	distal	5	no	8.897	9.050	PhosphoSitePlus	ICGC;COSMIC	3.716	Up-regulation
CAMK_PIM_PIM3_ST	P35568	IRS1	Q86V86	PIM3	S1105	S1106L	1106	Missense	proximal	1	no	4.113	4.350	EPSD	ICGC;COSMIC	3.716	Up-regulation
CAMK_PIM_PIM3_ST	P35568	IRS1	Q86V86	PIM3	S1105	R1112W	1112	Missense	distal	7	no	4.113	3.722	EPSD	ICGC;COSMIC	3.716	Down-regulation
CAMK_PIM_PIM3_ST	P35568	IRS1	Q86V86	PIM3	S1105	R1112G	1112	Missense	distal	7	no	4.113	3.759	EPSD	ICGC;COSMIC	3.716	Down-regulation
TK_Src_SrcB_LCK_Y	P06127	CD5	P06239	LCK	Y465	H461R	461	Missense	distal	-4	no	5.597	5.498	EPSD	ICGC	5.050	Down-regulation
TK_Src_SrcB_LCK_Y	P06127	CD5	P06239	LCK	Y465	A471V	471	Missense	distal	6	no	5.597	5.925	EPSD	ICGC	5.050	Up-regulation
TK_Src_SrcB_LCK_Y	P06127	CD5	P06239	LCK	Y465	Y465F	465	Missense	central	0	yes	5.597	0.000	EPSD	ICGC;COSMIC	5.050	Loss
TK_Src_SrcB_LCK_Y	P06127	CD5	P06239	LCK	Y487	D484N	484	Missense	distal	-3	no	6.371	5.396	EPSD;PhosphoSitePlus	ICGC;COSMIC	5.050	Down-regulation
TK_Src_SrcB_LCK_Y	Q9H204	MED28	P06239	LCK	Y64	D69Y	69	Missense	distal	5	no	6.252	6.332	PhosphoSitePlus	ICGC;COSMIC	5.050	Up-regulation
TK_Src_SrcB_LCK_Y	Q9H204	MED28	P06239	LCK	Y64	S61I	61	Missense	distal	-3	no	6.252	6.115	PhosphoSitePlus	ICGC	5.050	Down-regulation
TK_Src_SrcB_LCK_Y	P16885	PLCG2	P06239	LCK	Y743	M745I	745	Missense	proximal	2	no	5.745	4.491	EPSD	ICGC	5.050	Loss
TK_Src_SrcB_LCK_Y	P16885	PLCG2	P06239	LCK	Y743	R742C	742	Missense	proximal	-1	no	5.745	5.696	EPSD	ICGC;COSMIC	5.050	Down-regulation
TK_Src_SrcB_LCK_Y	P16885	PLCG2	P06239	LCK	Y743	D748Y	748	Missense	distal	5	no	5.745	5.825	EPSD	ICGC;COSMIC	5.050	Up-regulation
TK_Src_SrcB_LCK_Y	P16885	PLCG2	P06239	LCK	Y753	D748Y	748	Missense	distal	-5	no	5.520	4.927	PhosphoSitePlus;EPSD	ICGC;COSMIC	5.050	Loss
TK_Src_SrcB_LCK_Y	P16885	PLCG2	P06239	LCK	Y759	P762H	762	Missense	distal	3	no	5.707	6.501	EPSD;PhosphoSitePlus	ICGC;COSMIC	5.050	Up-regulation
TK_Src_SrcB_LCK_Y	P14784	IL2RB	P06239	LCK	Y384	D391E	391	Missense	distal	7	no	5.471	5.516	EPSD;PhosphoSitePlus	ICGC;COSMIC	5.050	Up-regulation
TK_Src_SrcB_LCK_Y	P14784	IL2RB	P06239	LCK	Y387	D391E	391	Missense	distal	4	no	6.102	6.355	EPSD;PhosphoSitePlus	ICGC;COSMIC	5.050	Up-regulation
TK_Src_SrcB_LCK_Y	P14784	IL2RB	P06239	LCK	Y418	D416N	416	Missense	proximal	-2	no	6.809	6.215	PhosphoSitePlus;EPSD	ICGC;COSMIC;GDSC;CCLE	5.050	Down-regulation
TK_Src_SrcB_LCK_Y	P14784	IL2RB	P06239	LCK	Y536	L531M	531	Missense	distal	-5	no	4.827	5.293	EPSD;PhosphoSitePlus	ICGC;COSMIC	5.050	Gain
TK_Src_SrcB_LCK_Y	P20963	CD247	P06239	LCK	Y83	K88N	88	Missense	distal	5	no	5.558	5.547	EPSD	ICGC;COSMIC	5.050	Down-regulation
TK_Src_SrcB_LCK_Y	P20963	CD247	P06239	LCK	Y83	R90S	90	Missense	distal	7	no	5.558	5.591	EPSD	ICGC	5.050	Up-regulation
TK_Src_SrcB_LCK_Y	P20963	CD247	P06239	LCK	Y111	P106H	106	Missense	distal	-5	no	7.974	7.837	EPSD	ICGC	5.050	Down-regulation
TK_Src_SrcB_LCK_Y	P20963	CD247	P06239	LCK	Y123	M128I	128	Missense	distal	5	no	7.621	7.721	EPSD	ICGC	5.050	Up-regulation
TK_Src_SrcB_LCK_Y	P20963	CD247	P06239	LCK	Y142	T147A	147	Missense	distal	5	no	8.002	7.977	PhosphoSitePlus	ICGC	5.050	Down-regulation
TK_Src_SrcB_LCK_Y	P20963	CD247	P06239	LCK	Y153	T147A	147	Missense	distal	-6	no	7.641	7.901	EPSD	ICGC	5.050	Up-regulation
TK_Src_SrcB_LCK_Y	P20963	CD247	P06239	LCK	Y153	D154Y	154	Missense	proximal	1	no	7.641	6.824	EPSD	ICGC;COSMIC	5.050	Down-regulation
TK_Src_SrcB_LCK_Y	P20963	CD247	P06239	LCK	Y153	L156I	156	Missense	distal	3	no	7.641	7.496	EPSD	ICGC	5.050	Down-regulation
TK_Src_SrcB_LCK_Y	Q9BWW4	SSBP3	P06239	LCK	Y23	L22S	22	Missense	proximal	-1	no	6.465	4.880	EPSD;PhosphoSitePlus	ICGC;COSMIC	5.050	Loss
TK_Src_SrcB_LCK_Y	Q9BWW4	SSBP3	P06239	LCK	Y23	H30Q	30	Missense	distal	7	no	6.465	6.542	EPSD;PhosphoSitePlus	ICGC;COSMIC	5.050	Up-regulation
TK_Src_SrcB_LCK_Y	Q9BWW4	SSBP3	P06239	LCK	Y25	L22S	22	Missense	distal	-3	no	5.842	6.371	PhosphoSitePlus;EPSD	ICGC;COSMIC	5.050	Up-regulation
TK_Src_SrcB_LCK_Y	Q9BWW4	SSBP3	P06239	LCK	Y25	H30Q	30	Missense	distal	5	no	5.842	5.811	PhosphoSitePlus;EPSD	ICGC;COSMIC	5.050	Down-regulation
TK_Src_SrcB_LCK_Y	Q9BWW4	SSBP3	P06239	LCK	Y25	V31I	31	Missense	distal	6	no	5.842	5.785	PhosphoSitePlus;EPSD	ICGC;COSMIC	5.050	Down-regulation
TK_Src_SrcB_LCK_Y	P43403	ZAP70	P06239	LCK	Y69	G67S	67	Missense	proximal	-2	no	6.106	6.188	EPSD;PhosphoSitePlus	ICGC;COSMIC	5.050	Up-regulation
TK_Src_SrcB_LCK_Y	P43403	ZAP70	P06239	LCK	Y69	A70T	70	Missense	proximal	1	no	6.106	6.634	EPSD;PhosphoSitePlus	ICGC;COSMIC	5.050	Up-regulation
TK_Src_SrcB_LCK_Y	P43403	ZAP70	P06239	LCK	Y69	G73S	73	Missense	distal	4	no	6.106	6.460	EPSD;PhosphoSitePlus	ICGC;COSMIC	5.050	Up-regulation
TK_Src_SrcB_LCK_Y	P43403	ZAP70	P06239	LCK	Y69	E62D	62	Missense	distal	-7	no	6.106	5.758	EPSD;PhosphoSitePlus	ICGC	5.050	Down-regulation
TK_Src_SrcB_LCK_Y	P43403	ZAP70	P06239	LCK	Y126	R124C	124	Missense	proximal	-2	no	6.232	4.815	EPSD;PhosphoSitePlus	ICGC;COSMIC	5.050	Loss
TK_Src_SrcB_LCK_Y	P43403	ZAP70	P06239	LCK	Y178	A173S	173	Missense	distal	-5	no	7.005	7.008	EPSD;PhosphoSitePlus	ICGC	5.050	Up-regulation
TK_Src_SrcB_LCK_Y	P43403	ZAP70	P06239	LCK	Y178	G185V	185	Missense	distal	7	no	7.005	6.803	EPSD;PhosphoSitePlus	ICGC	5.050	Down-regulation
TK_Src_SrcB_LCK_Y	P43403	ZAP70	P06239	LCK	Y178	E174K	174	Missense	distal	-4	no	7.005	6.202	EPSD;PhosphoSitePlus	ICGC;COSMIC	5.050	Down-regulation
TK_Src_SrcB_LCK_Y	P43403	ZAP70	P06239	LCK	Y178	G180W	180	Missense	proximal	2	no	7.005	6.120	EPSD;PhosphoSitePlus	ICGC;COSMIC	5.050	Down-regulation
TK_Src_SrcB_LCK_Y	P43403	ZAP70	P06239	LCK	Y315	P318L	318	Missense	distal	3	no	7.852	8.568	PhosphoSitePlus;EPSD	ICGC;COSMIC	5.050	Up-regulation
TK_Src_SrcB_LCK_Y	P43403	ZAP70	P06239	LCK	Y319	K326N	326	Missense	distal	7	no	8.248	8.224	EPSD;PhosphoSitePlus	ICGC	5.050	Down-regulation
TK_Src_SrcB_LCK_Y	P43403	ZAP70	P06239	LCK	Y319	P318L	318	Missense	proximal	-1	no	8.248	9.457	EPSD;PhosphoSitePlus	ICGC;COSMIC	5.050	Up-regulation
TK_Src_SrcB_LCK_Y	P43403	ZAP70	P06239	LCK	Y357	R360L	360	Missense	distal	3	no	4.523	5.571	EPSD	ICGC	5.050	Gain
TK_Src_SrcB_LCK_Y	P43403	ZAP70	P06239	LCK	Y474	H473D	473	Missense	proximal	-1	no	6.933	7.830	EPSD;PhosphoSitePlus	ICGC;COSMIC	5.050	Up-regulation
TK_Src_SrcB_LCK_Y	P43403	ZAP70	P06239	LCK	Y474	R472W	472	Missense	proximal	-2	no	6.933	5.618	EPSD;PhosphoSitePlus	ICGC;COSMIC	5.050	Down-regulation
TK_Src_SrcB_LCK_Y	P43403	ZAP70	P06239	LCK	Y474	L468M	468	Missense	distal	-6	no	6.933	7.166	EPSD;PhosphoSitePlus	ICGC;COSMIC	5.050	Up-regulation
TK_Src_SrcB_LCK_Y	P43403	ZAP70	P06239	LCK	Y569	A570T	570	Missense	proximal	1	no	7.233	7.761	EPSD	ICGC;COSMIC;GDSC;CCLE	5.050	Up-regulation
TK_Src_SrcB_LCK_Y	P06239	LCK	P06239	LCK	Y505	E502D	502	Missense	distal	-3	no	6.755	7.326	PhosphoSitePlus;EPSD	ICGC	5.050	Up-regulation
TK_Src_SrcB_LCK_Y	P15498	VAV1	P06239	LCK	Y142	G144D	144	Missense	proximal	2	no	7.950	8.028	EPSD;PhosphoSitePlus	ICGC;COSMIC	5.050	Up-regulation
TK_Src_SrcB_LCK_Y	P15498	VAV1	P06239	LCK	Y142	D140N	140	Missense	proximal	-2	no	7.950	7.355	EPSD;PhosphoSitePlus	ICGC;COSMIC	5.050	Down-regulation
TK_Src_SrcB_LCK_Y	P15498	VAV1	P06239	LCK	Y142	D138G	138	Missense	distal	-4	no	7.950	7.046	EPSD;PhosphoSitePlus	ICGC	5.050	Down-regulation
TK_Src_SrcB_LCK_Y	P15498	VAV1	P06239	LCK	Y160	E167V	167	Missense	distal	7	no	10.123	9.778	PhosphoSitePlus;EPSD	ICGC	5.050	Down-regulation
TK_Src_SrcB_LCK_Y	P15498	VAV1	P06239	LCK	Y160	E157D	157	Missense	distal	-3	no	10.123	10.695	PhosphoSitePlus;EPSD	ICGC;COSMIC	5.050	Up-regulation
TK_Src_SrcB_LCK_Y	P15498	VAV1	P06239	LCK	Y160	E166A	166	Missense	distal	6	no	10.123	10.642	PhosphoSitePlus;EPSD	ICGC;COSMIC	5.050	Up-regulation
TK_Src_SrcB_LCK_Y	P15498	VAV1	P06239	LCK	Y160	E154A	154	Missense	distal	-6	no	10.123	9.725	PhosphoSitePlus;EPSD	ICGC;COSMIC	5.050	Down-regulation
TK_Src_SrcB_LCK_Y	P15498	VAV1	P06239	LCK	Y174	E167V	167	Missense	distal	-7	no	10.500	10.037	EPSD;PhosphoSitePlus	ICGC	5.050	Down-regulation
TK_Src_SrcB_LCK_Y	P15498	VAV1	P06239	LCK	Y174	E169K	169	Missense	distal	-5	no	10.500	9.840	EPSD;PhosphoSitePlus	ICGC	5.050	Down-regulation
TK_Src_SrcB_LCK_Y	P15498	VAV1	P06239	LCK	Y174	E172D	172	Missense	proximal	-2	no	10.500	10.750	EPSD;PhosphoSitePlus	ICGC	5.050	Up-regulation
TK_Src_SrcB_LCK_Y	P15498	VAV1	P06239	LCK	Y192	C198Y	198	Missense	distal	6	no	5.052	4.326	EPSD	ICGC	5.050	Loss
TK_Src_SrcB_LCK_Y	P15498	VAV1	P06239	LCK	Y192	M185T	185	Missense	distal	-7	no	5.052	4.790	EPSD	ICGC;COSMIC	5.050	Loss
TK_Src_SrcB_LCK_Y	P15498	VAV1	P06239	LCK	Y603	G605W	605	Missense	proximal	2	no	5.374	4.489	EPSD	ICGC;COSMIC	5.050	Loss
TK_Src_SrcB_LCK_Y	P15498	VAV1	P06239	LCK	Y603	K596N	596	Missense	distal	-7	no	5.374	5.420	EPSD	ICGC;CCLE	5.050	Up-regulation
TK_Src_SrcB_LCK_Y	P15498	VAV1	P06239	LCK	Y603	P609S	609	Missense	distal	6	no	5.374	4.937	EPSD	ICGC;COSMIC	5.050	Loss
TK_Src_SrcB_LCK_Y	P15498	VAV1	P06239	LCK	Y791	R790L	790	Missense	proximal	-1	no	3.470	5.136	EPSD	ICGC;COSMIC	5.050	Gain
TK_Src_SrcB_LCK_Y	Q13094	LCP2	P06239	LCK	Y113	P116H	116	Missense	distal	3	no	8.611	9.405	EPSD;PhosphoSitePlus	ICGC	5.050	Up-regulation
TK_Src_SrcB_LCK_Y	Q13094	LCP2	P06239	LCK	Y128	S130F	130	Missense	proximal	2	no	9.064	8.228	EPSD;PhosphoSitePlus	ICGC	5.050	Down-regulation
TK_Src_SrcB_LCK_Y	Q13094	LCP2	P06239	LCK	Y128	G122W	122	Missense	distal	-6	no	9.064	8.616	EPSD;PhosphoSitePlus	ICGC;COSMIC	5.050	Down-regulation
TK_Src_SrcB_LCK_Y	Q13094	LCP2	P06239	LCK	Y145	P147L	147	Missense	proximal	2	no	8.816	7.642	PhosphoSitePlus;EPSD	ICGC;COSMIC	5.050	Down-regulation
TK_Src_SrcB_LCK_Y	Q8N1K5	THEMIS	P06239	LCK	Y540	R544L	544	Missense	distal	4	no	8.032	7.296	EPSD;PhosphoSitePlus	ICGC;COSMIC	5.050	Down-regulation
TK_Src_SrcB_LCK_Y	Q8N1K5	THEMIS	P06239	LCK	Y540	R544Q	544	Missense	distal	4	no	8.032	7.920	EPSD;PhosphoSitePlus	ICGC;COSMIC;GDSC;CCLE	5.050	Down-regulation
TK_Src_SrcB_LCK_Y	Q8N1K5	THEMIS	P06239	LCK	Y540	Y546C	546	Missense	distal	6	no	8.032	8.758	EPSD;PhosphoSitePlus	ICGC;COSMIC	5.050	Up-regulation
TK_Src_SrcB_LCK_Y	Q8N1K5	THEMIS	P06239	LCK	Y541	R544L	544	Missense	distal	3	no	6.248	7.296	PhosphoSitePlus;EPSD	ICGC;COSMIC	5.050	Up-regulation
TK_Src_SrcB_LCK_Y	Q8N1K5	THEMIS	P06239	LCK	Y541	S548T	548	Missense	distal	7	no	6.248	6.066	PhosphoSitePlus;EPSD	ICGC;COSMIC	5.050	Down-regulation
TK_Src_SrcB_LCK_Y	Q8N1K5	THEMIS	P06239	LCK	Y541	R544Q	544	Missense	distal	3	no	6.248	6.267	PhosphoSitePlus;EPSD	ICGC;COSMIC;GDSC;CCLE	5.050	Up-regulation
TK_Src_SrcB_LCK_Y	Q8N1K5	THEMIS	P06239	LCK	Y541	Y546C	546	Missense	distal	5	no	6.248	6.488	PhosphoSitePlus;EPSD	ICGC;COSMIC	5.050	Up-regulation
TK_Src_SrcB_LCK_Y	Q16539	MAPK14	P06239	LCK	Y323	D321N	321	Missense	proximal	-2	no	6.587	5.992	PhosphoSitePlus	ICGC	5.050	Down-regulation
TK_Src_SrcB_LCK_Y	P42229	STAT5A	P06239	LCK	Y171	Q175H	175	Missense	distal	4	no	6.645	6.420	EPSD	ICGC;COSMIC	5.050	Down-regulation
TK_Src_SrcB_LCK_Y	P42229	STAT5A	P06239	LCK	Y668	G661W	661	Missense	distal	-7	no	5.431	5.310	EPSD	ICGC;COSMIC	5.050	Down-regulation
TK_Src_SrcB_LCK_Y	Q13291	SLAMF1	P06239	LCK	Y269	T272A	272	Missense	distal	3	no	5.449	6.254	EPSD	ICGC;COSMIC	5.050	Up-regulation
TK_Src_SrcB_LCK_Y	Q13291	SLAMF1	P06239	LCK	Y281	A282D	282	Missense	proximal	1	no	5.141	6.230	EPSD	ICGC	5.050	Up-regulation
TK_Src_SrcB_LCK_Y	Q13291	SLAMF1	P06239	LCK	Y281	A282V	282	Missense	proximal	1	no	5.141	5.030	EPSD	ICGC;COSMIC	5.050	Loss
TK_Src_SrcB_LCK_Y	Q13291	SLAMF1	P06239	LCK	Y281	S277R	277	Missense	distal	-4	no	5.141	4.745	EPSD	ICGC	5.050	Loss
TK_Src_SrcB_LCK_Y	Q13291	SLAMF1	P06239	LCK	Y307	T311I	311	Missense	distal	4	no	7.153	6.658	PhosphoSitePlus	ICGC	5.050	Down-regulation
TK_Src_SrcB_LCK_Y	Q13291	SLAMF1	P06239	LCK	Y307	P313H	313	Missense	distal	6	no	7.153	6.718	PhosphoSitePlus	ICGC;COSMIC	5.050	Down-regulation
TK_Src_SrcB_LCK_Y	Q13291	SLAMF1	P06239	LCK	Y307	A310S	310	Missense	distal	3	no	7.153	6.830	PhosphoSitePlus	ICGC;COSMIC	5.050	Down-regulation
TK_Src_SrcB_LCK_Y	Q13291	SLAMF1	P06239	LCK	Y307	P302L	302	Missense	distal	-5	no	7.153	6.893	PhosphoSitePlus	ICGC;COSMIC	5.050	Down-regulation
TK_Src_SrcB_LCK_Y	Q13291	SLAMF1	P06239	LCK	Y307	V308I	308	Missense	proximal	1	no	7.153	6.972	PhosphoSitePlus	ICGC	5.050	Down-regulation
TK_Src_SrcB_LCK_Y	Q13291	SLAMF1	P06239	LCK	Y307	V308F	308	Missense	proximal	1	no	7.153	6.982	PhosphoSitePlus	ICGC;COSMIC	5.050	Down-regulation
TK_Src_SrcB_LCK_Y	Q13291	SLAMF1	P06239	LCK	Y327	P333T	333	Missense	distal	6	no	7.182	7.079	EPSD	ICGC;COSMIC	5.050	Down-regulation
TK_Src_SrcB_LCK_Y	Q13291	SLAMF1	P06239	LCK	Y327	P333Q	333	Missense	distal	6	no	7.182	7.272	EPSD	ICGC	5.050	Up-regulation
TK_Src_SrcB_LCK_Y	Q13444	ADAM15	P06239	LCK	Y735	S740L	740	Missense	distal	5	no	6.300	6.495	EPSD	ICGC;COSMIC	5.050	Up-regulation
TK_Src_SrcB_LCK_Y	Q13444	ADAM15	P06239	LCK	Y735	R736S	736	Missense	proximal	1	no	6.300	6.296	EPSD	ICGC;COSMIC	5.050	Down-regulation
TK_Src_SrcB_LCK_Y	P22681	CBL	P06239	LCK	Y141	G136V	136	Missense	distal	-5	no	6.165	6.015	EPSD	ICGC	5.050	Down-regulation
TK_Src_SrcB_LCK_Y	P22681	CBL	P06239	LCK	Y368	Y371H	371	Missense	distal	3	no	3.875	5.418	EPSD	ICGC;COSMIC	5.050	Gain
TK_Src_SrcB_LCK_Y	P22681	CBL	P06239	LCK	Y371	Y371H	371	Missense	central	0	yes	5.315	0.000	EPSD	ICGC;COSMIC	5.050	Loss
TK_Src_SrcB_LCK_Y	P22681	CBL	P06239	LCK	Y371	E366K	366	Missense	distal	-5	no	5.315	4.655	EPSD	ICGC;COSMIC	5.050	Loss
TK_Src_SrcB_LCK_Y	P22681	CBL	P06239	LCK	Y371	Y368C	368	Missense	distal	-3	no	5.315	3.600	EPSD	ICGC;COSMIC	5.050	Loss
TK_Src_SrcB_LCK_Y	P22681	CBL	P06239	LCK	Y455	D459V	459	Missense	distal	4	no	5.839	4.833	EPSD	ICGC;COSMIC	5.050	Loss
TK_Src_SrcB_LCK_Y	P22681	CBL	P06239	LCK	Y700	M701L	701	Missense	proximal	1	no	8.996	8.687	PhosphoSitePlus;EPSD	ICGC;COSMIC	5.050	Down-regulation
TK_Src_SrcB_LCK_Y	P22681	CBL	P06239	LCK	Y700	E696D	696	Missense	distal	-4	no	8.996	8.920	PhosphoSitePlus;EPSD	ICGC;COSMIC	5.050	Down-regulation
TK_Src_SrcB_LCK_Y	P22681	CBL	P06239	LCK	Y700	E693D	693	Missense	distal	-7	no	8.996	8.648	PhosphoSitePlus;EPSD	ICGC;COSMIC	5.050	Down-regulation
TK_Src_SrcB_LCK_Y	P22681	CBL	P06239	LCK	Y731	Y731H	731	Missense	central	0	yes	8.083	0.000	EPSD;PhosphoSitePlus	ICGC;COSMIC	5.050	Loss
TK_Src_SrcB_LCK_Y	P22681	CBL	P06239	LCK	Y774	G773E	773	Missense	proximal	-1	no	8.964	10.818	EPSD;PhosphoSitePlus	ICGC	5.050	Up-regulation
TK_Src_SrcB_LCK_Y	P60484	PTEN	P06239	LCK	Y68	L70P	70	Missense	proximal	2	no	4.757	5.931	EPSD	ICGC;COSMIC	5.050	Gain
TK_Src_SrcB_LCK_Y	P60484	PTEN	P06239	LCK	Y155	V158I	158	Missense	distal	3	no	5.347	5.400	EPSD	ICGC;COSMIC	5.050	Up-regulation
TK_Src_SrcB_LCK_Y	P60484	PTEN	P06239	LCK	Y155	V158G	158	Missense	distal	3	no	5.347	4.512	EPSD	ICGC	5.050	Loss
TK_Src_SrcB_LCK_Y	P60484	PTEN	P06239	LCK	Y155	G156V	156	Missense	proximal	1	no	5.347	5.341	EPSD	ICGC;COSMIC	5.050	Down-regulation
TK_Src_SrcB_LCK_Y	P60484	PTEN	P06239	LCK	Y155	L152R	152	Missense	distal	-3	no	5.347	6.446	EPSD	ICGC;COSMIC	5.050	Up-regulation
TK_Src_SrcB_LCK_Y	P60484	PTEN	P06239	LCK	Y155	F154C	154	Missense	proximal	-1	no	5.347	4.439	EPSD	ICGC;COSMIC	5.050	Loss
TK_Src_SrcB_LCK_Y	P60484	PTEN	P06239	LCK	Y176	Y177C	177	Missense	proximal	1	no	5.532	4.399	EPSD	ICGC;COSMIC	5.050	Loss
TK_Src_SrcB_LCK_Y	P60484	PTEN	P06239	LCK	Y176	Y177S	177	Missense	proximal	1	no	5.532	5.324	EPSD	ICGC;COSMIC	5.050	Down-regulation
TK_Src_SrcB_LCK_Y	P60484	PTEN	P06239	LCK	Y176	Y178S	178	Missense	proximal	2	no	5.532	6.456	EPSD	ICGC;COSMIC	5.050	Up-regulation
TK_Src_SrcB_LCK_Y	P60484	PTEN	P06239	LCK	Y176	V175L	175	Missense	proximal	-1	no	5.532	5.188	EPSD	ICGC;COSMIC	5.050	Down-regulation
TK_Src_SrcB_LCK_Y	P60484	PTEN	P06239	LCK	Y240	P244R	244	Missense	distal	4	no	6.412	6.732	EPSD;PhosphoSitePlus	ICGC;COSMIC	5.050	Up-regulation
TK_Src_SrcB_LCK_Y	P60484	PTEN	P06239	LCK	Y315	D312Y	312	Missense	distal	-3	no	6.389	5.230	PhosphoSitePlus;EPSD	ICGC	5.050	Down-regulation
TK_Src_SrcB_LCK_Y	Q04759	PRKCQ	P06239	LCK	Y90	E88K	88	Missense	proximal	-2	no	7.972	7.402	PhosphoSitePlus	ICGC;COSMIC	5.050	Down-regulation
TK_Src_SrcB_LCK_Y	Q04759	PRKCQ	P06239	LCK	Y90	A93V	93	Missense	distal	3	no	7.972	7.827	PhosphoSitePlus	ICGC;COSMIC	5.050	Down-regulation
TK_Src_SrcB_LCK_Y	P05107	ITGB2	P06239	LCK	Y735	R733W	733	Missense	proximal	-2	no	5.684	4.370	PhosphoSitePlus	ICGC;COSMIC	5.050	Loss
TK_Src_SrcB_LCK_Y	P05107	ITGB2	P06239	LCK	Y735	R737G	737	Missense	proximal	2	no	5.684	5.875	PhosphoSitePlus	ICGC;COSMIC	5.050	Up-regulation
TK_Src_SrcB_LCK_Y	P05107	ITGB2	P06239	LCK	Y735	R736K	736	Missense	proximal	1	no	5.684	5.661	PhosphoSitePlus	ICGC;COSMIC	5.050	Down-regulation
TK_Src_SrcB_LCK_Y	P05107	ITGB2	P06239	LCK	Y735	F738C	738	Missense	distal	3	no	5.684	4.632	PhosphoSitePlus	ICGC;COSMIC	5.050	Loss
TK_Src_SrcB_LCK_Y	P05107	ITGB2	P06239	LCK	Y735	L732F	732	Missense	distal	-3	no	5.684	5.960	PhosphoSitePlus	ICGC	5.050	Up-regulation
TK_Src_SrcB_LCK_Y	P05107	ITGB2	P06239	LCK	Y735	R737C	737	Missense	proximal	2	no	5.684	4.622	PhosphoSitePlus	ICGC;COSMIC;CCLE	5.050	Loss
TK_Src_SrcB_LCK_Y	P05107	ITGB2	P06239	LCK	Y735	R733L	733	Missense	proximal	-2	no	5.684	4.671	PhosphoSitePlus	ICGC;COSMIC	5.050	Loss
TK_Src_SrcB_LCK_Y	P24666	ACP1	P06239	LCK	Y132	I127M	127	Missense	distal	-5	no	6.956	7.990	PhosphoSitePlus;EPSD	ICGC;COSMIC	5.050	Up-regulation
TK_Src_SrcB_LCK_Y	P24666	ACP1	P06239	LCK	Y132	I128F	128	Missense	distal	-4	no	6.956	6.653	PhosphoSitePlus;EPSD	ICGC;COSMIC	5.050	Down-regulation
TK_Src_SrcB_LCK_Y	P24666	ACP1	P06239	LCK	Y132	Y132C	132	Missense	central	0	yes	6.956	0.000	PhosphoSitePlus;EPSD	ICGC;COSMIC	5.050	Loss
TK_Src_SrcB_LCK_Y	P24666	ACP1	P06239	LCK	Y133	I127M	127	Missense	distal	-6	no	5.981	6.888	EPSD;PhosphoSitePlus	ICGC;COSMIC	5.050	Up-regulation
TK_Src_SrcB_LCK_Y	P24666	ACP1	P06239	LCK	Y133	I128F	128	Missense	distal	-5	no	5.981	6.069	EPSD;PhosphoSitePlus	ICGC;COSMIC	5.050	Up-regulation
TK_Src_SrcB_LCK_Y	P24666	ACP1	P06239	LCK	Y133	Y132C	132	Missense	proximal	-1	no	5.981	5.528	EPSD;PhosphoSitePlus	ICGC;COSMIC	5.050	Down-regulation
TK_Src_SrcB_LCK_Y	P03372	ESR1	P06239	LCK	Y537	Y537C	537	Missense	central	0	yes	5.669	0.000	PhosphoSitePlus	ICGC;COSMIC	5.050	Loss
TK_Src_SrcB_LCK_Y	P03372	ESR1	P06239	LCK	Y537	K531M	531	Missense	distal	-6	no	5.669	5.963	PhosphoSitePlus	ICGC;COSMIC	5.050	Up-regulation
TK_Src_SrcB_LCK_Y	P03372	ESR1	P06239	LCK	Y537	P535L	535	Missense	proximal	-2	no	5.669	4.682	PhosphoSitePlus	ICGC;COSMIC	5.050	Loss
TK_Src_SrcB_LCK_Y	P03372	ESR1	P06239	LCK	Y537	K531N	531	Missense	distal	-6	no	5.669	5.823	PhosphoSitePlus	ICGC	5.050	Up-regulation
TK_Src_SrcB_LCK_Y	P03372	ESR1	P06239	LCK	Y537	C530F	530	Missense	distal	-7	no	5.669	6.025	PhosphoSitePlus	ICGC	5.050	Up-regulation
TK_Src_SrcB_LCK_Y	P25963	NFKBIA	P06239	LCK	Y42	E48Q	48	Missense	distal	6	no	8.519	9.343	PhosphoSitePlus	ICGC;COSMIC	5.050	Up-regulation
TK_Src_SrcB_LCK_Y	P25963	NFKBIA	P06239	LCK	Y42	E48D	48	Missense	distal	6	no	8.519	9.157	PhosphoSitePlus	ICGC;COSMIC	5.050	Up-regulation
TK_Src_SrcB_LCK_Y	P25963	NFKBIA	P06239	LCK	Y42	K38T	38	Missense	distal	-4	no	8.519	8.751	PhosphoSitePlus	ICGC	5.050	Up-regulation
TK_Src_SrcB_LCK_Y	O14543	SOCS3	P06239	LCK	Y204	D202E	202	Missense	proximal	-2	no	5.655	5.406	EPSD;PhosphoSitePlus	ICGC;COSMIC	5.050	Down-regulation
TK_Src_SrcB_LCK_Y	Q13283	G3BP1	P06239	LCK	Y56	E60D	60	Missense	distal	4	no	7.436	7.182	PhosphoSitePlus	ICGC	5.050	Down-regulation
TK_Src_SrcB_LCK_Y	Q13283	G3BP1	P06239	LCK	Y56	P51L	51	Missense	distal	-5	no	7.436	7.176	PhosphoSitePlus	ICGC;COSMIC	5.050	Down-regulation
TK_Src_SrcB_LCK_Y	Q13283	G3BP1	P06239	LCK	Y174	S180G	180	Missense	distal	6	no	6.195	6.813	EPSD	ICGC	5.050	Up-regulation
TK_Src_SrcB_LCK_Y	Q13283	G3BP1	P06239	LCK	Y174	V179F	179	Missense	distal	5	no	6.195	6.156	EPSD	ICGC;COSMIC	5.050	Down-regulation
TK_Src_SrcB_LCK_Y	Q08881	ITK	P06239	LCK	Y512	D510A	510	Missense	proximal	-2	no	7.871	6.815	PhosphoSitePlus	ICGC	5.050	Down-regulation
TK_Src_SrcB_LCK_Y	P15311	EZR	P06239	LCK	Y116	I110T	110	Missense	distal	-6	no	5.031	5.867	EPSD	ICGC	5.050	Gain
TK_Src_SrcB_LCK_Y	P15311	EZR	P06239	LCK	Y146	H142Q	142	Missense	distal	-4	no	6.198	6.446	PhosphoSitePlus	ICGC;COSMIC	5.050	Up-regulation
TK_Src_SrcB_LCK_Y	P15311	EZR	P06239	LCK	Y146	H142N	142	Missense	distal	-4	no	6.198	6.484	PhosphoSitePlus	ICGC;COSMIC	5.050	Up-regulation
TK_Src_SrcB_LCK_Y	P15311	EZR	P06239	LCK	Y205	F206L	206	Missense	proximal	1	no	5.003	5.306	EPSD	ICGC	5.050	Gain
TK_Src_SrcB_LCK_Y	P15311	EZR	P06239	LCK	Y354	K357T	357	Missense	distal	3	no	4.572	5.080	EPSD	ICGC;COSMIC	5.050	Gain
TK_Src_SrcB_LCK_Y	P15311	EZR	P06239	LCK	Y424	L421I	421	Missense	distal	-3	no	6.018	6.410	EPSD	ICGC	5.050	Up-regulation
TK_Src_SrcB_LCK_Y	P15311	EZR	P06239	LCK	Y424	A418D	418	Missense	distal	-6	no	6.018	5.920	EPSD	ICGC	5.050	Down-regulation
TK_Src_SrcB_LCK_Y	P15311	EZR	P06239	LCK	Y478	P471L	471	Missense	distal	-7	no	6.042	6.109	EPSD	ICGC;COSMIC;GDSC	5.050	Up-regulation
TK_Src_SrcB_LCK_Y	P15311	EZR	P06239	LCK	Y478	P471Q	471	Missense	distal	-7	no	6.042	6.029	EPSD	ICGC	5.050	Down-regulation
TK_Src_SrcB_LCK_Y	P15311	EZR	P06239	LCK	Y478	P472T	472	Missense	distal	-6	no	6.042	6.113	EPSD	ICGC	5.050	Up-regulation
TK_Src_SrcB_LCK_Y	P42768	WAS	P06239	LCK	Y54	A47S	47	Missense	distal	-7	no	6.238	6.119	EPSD	ICGC	5.050	Down-regulation
TK_Src_SrcB_LCK_Y	P42768	WAS	P06239	LCK	Y291	D292Y	292	Missense	proximal	1	no	9.097	8.280	PhosphoSitePlus	ICGC;COSMIC	5.050	Down-regulation
TK_Src_SrcB_LCK_Y	P42768	WAS	P06239	LCK	Y291	A284S	284	Missense	distal	-7	no	9.097	8.978	PhosphoSitePlus	ICGC	5.050	Down-regulation
TK_Src_SrcB_LCK_Y	P42768	WAS	P06239	LCK	Y291	I290M	290	Missense	proximal	-1	no	9.097	8.215	PhosphoSitePlus	ICGC;COSMIC	5.050	Down-regulation
TK_Src_SrcB_LCK_Y	P42768	WAS	P06239	LCK	Y291	E285K	285	Missense	distal	-6	no	9.097	8.216	PhosphoSitePlus	ICGC;COSMIC	5.050	Down-regulation
TK_Src_SrcB_LCK_Y	Q9UHD2	TBK1	P06239	LCK	Y153	E147K	147	Missense	distal	-6	no	5.423	4.542	EPSD	ICGC;COSMIC	5.050	Loss
TK_Src_SrcB_LCK_Y	Q9UHD2	TBK1	P06239	LCK	Y153	Q150H	150	Missense	distal	-3	no	5.423	4.287	EPSD	ICGC;COSMIC	5.050	Loss
TK_Src_SrcB_LCK_Y	Q9UHD2	TBK1	P06239	LCK	Y153	A160S	160	Missense	distal	7	no	5.423	5.531	EPSD	ICGC	5.050	Up-regulation
TK_Src_SrcB_LCK_Y	Q9UHD2	TBK1	P06239	LCK	Y153	D148H	148	Missense	distal	-5	no	5.423	5.436	EPSD	ICGC;COSMIC	5.050	Up-regulation
TK_Src_SrcB_LCK_Y	Q9UHD2	TBK1	P06239	LCK	Y185	H181Q	181	Missense	distal	-4	no	5.617	5.865	EPSD	ICGC;COSMIC	5.050	Up-regulation
TK_Src_SrcB_LCK_Y	Q9UHD2	TBK1	P06239	LCK	Y394	T389I	389	Missense	distal	-5	no	7.865	7.211	EPSD;PhosphoSitePlus	ICGC;COSMIC	5.050	Down-regulation
TK_Src_SrcB_LCK_Y	Q9UHD2	TBK1	P06239	LCK	Y394	P400S	400	Missense	distal	6	no	7.865	7.428	EPSD;PhosphoSitePlus	ICGC;COSMIC	5.050	Down-regulation
TK_Src_SrcB_LCK_Y	Q9UHD2	TBK1	P06239	LCK	Y394	P400H	400	Missense	distal	6	no	7.865	7.430	EPSD;PhosphoSitePlus	ICGC;COSMIC	5.050	Down-regulation
TK_Src_SrcB_LCK_Y	Q9UN19	DAPP1	P06239	LCK	Y139	V142A	142	Missense	distal	3	no	9.733	9.879	PhosphoSitePlus	ICGC;COSMIC	5.050	Up-regulation
TK_Src_SrcB_LCK_Y	Q9UN19	DAPP1	P06239	LCK	Y139	I138V	138	Missense	proximal	-1	no	9.733	9.348	PhosphoSitePlus	ICGC;COSMIC	5.050	Down-regulation
TK_Src_SrcB_LCK_Y	P12235	SLC25A4	P06239	LCK	Y195	R188K	188	Missense	distal	-7	no	5.926	5.691	PhosphoSitePlus	ICGC;COSMIC	5.050	Down-regulation
TK_Met_MST1R_Y	P08581	MET	Q04912	MST1R	Y1003	P1008S	1008	Missense	distal	5	no	0.001	0.000	EPSD	ICGC;COSMIC	0.001	Loss
TK_Met_MST1R_Y	P08581	MET	Q04912	MST1R	Y1003	R1004Q	1004	Missense	proximal	1	no	0.001	0.000	EPSD	ICGC;COSMIC	0.001	Loss
TK_Met_MST1R_Y	P08581	MET	Q04912	MST1R	Y1093	Y1093N	1093	Missense	central	0	yes	0.001	0.000	EPSD	ICGC;COSMIC	0.001	Loss
TK_Met_MST1R_Y	P08581	MET	Q04912	MST1R	Y1093	T1096S	1096	Missense	distal	3	no	0.001	0.000	EPSD	ICGC;COSMIC	0.001	Loss
TK_Met_MST1R_Y	P08581	MET	Q04912	MST1R	Y1194	M1192I	1192	Missense	proximal	-2	no	0.001	0.002	EPSD	ICGC;COSMIC	0.001	Up-regulation
TK_Met_MST1R_Y	P08581	MET	Q04912	MST1R	Y1235	Y1235H	1235	Missense	central	0	yes	0.003	0.000	EPSD;PhosphoSitePlus	ICGC;COSMIC	0.001	Loss
TK_Met_MST1R_Y	P08581	MET	Q04912	MST1R	Y1356	Y1356C	1356	Missense	central	0	yes	0.002	0.000	PhosphoSitePlus;EPSD	ICGC;COSMIC	0.001	Loss
TK_Ret_RET_Y	P40763	STAT3	Q15300	RET	Y539	N538K	538	Missense	proximal	-1	no	30.476	30.443	EPSD	ICGC;COSMIC	28.094	Down-regulation
TK_Ret_RET_Y	P40763	STAT3	Q15300	RET	Y539	L533F	533	Missense	distal	-6	no	30.476	30.429	EPSD	ICGC;COSMIC	28.094	Down-regulation
TK_Ret_RET_Y	P40763	STAT3	Q15300	RET	Y539	G541W	541	Missense	proximal	2	no	30.476	30.258	EPSD	ICGC;COSMIC	28.094	Down-regulation
TK_Ret_RET_Y	P40763	STAT3	Q15300	RET	Y686	P689T	689	Missense	distal	3	no	28.945	28.382	EPSD	ICGC	28.094	Down-regulation
TK_Ret_RET_Y	P40763	STAT3	Q15300	RET	Y686	S691C	691	Missense	distal	5	no	28.945	28.464	EPSD	ICGC;COSMIC	28.094	Down-regulation
TK_Ret_RET_Y	P40763	STAT3	Q15300	RET	Y686	R688W	688	Missense	proximal	2	no	28.945	28.528	EPSD	ICGC;COSMIC;GDSC;CCLE	28.094	Down-regulation
Other_KIS_UHMK1_ST	P46527	CDKN1B	Q8TAS1	UHMK1	S10	N8K	8	Missense	proximal	-2	no	4.134	3.963	PhosphoSitePlus	ICGC;COSMIC	1.522	Down-regulation
Other_KIS_UHMK1_ST	P46527	CDKN1B	Q8TAS1	UHMK1	S112	V109G	109	Missense	distal	-3	no	1.641	1.615	EPSD	ICGC;COSMIC	1.522	Down-regulation
Other_KIS_UHMK1_ST	P46527	CDKN1B	Q8TAS1	UHMK1	S178	V184M	184	Missense	distal	6	no	1.784	1.797	EPSD	ICGC;COSMIC	1.522	Up-regulation
Other_KIS_UHMK1_ST	P46527	CDKN1B	Q8TAS1	UHMK1	S178	G182C	182	Missense	distal	4	no	1.784	1.921	EPSD	ICGC	1.522	Up-regulation
Other_KIS_UHMK1_ST	P46527	CDKN1B	Q8TAS1	UHMK1	S178	G177V	177	Missense	proximal	-1	no	1.784	1.414	EPSD	ICGC	1.522	Loss
Other_KIS_UHMK1_ST	P46527	CDKN1B	Q8TAS1	UHMK1	S178	S178F	178	Missense	central	0	yes	1.784	0.000	EPSD	ICGC;COSMIC	1.522	Loss
Other_KIS_UHMK1_ST	P16949	STMN1	Q8TAS1	UHMK1	S25	L24F	24	Missense	proximal	-1	no	2.925	2.895	EPSD	ICGC;COSMIC	1.522	Down-regulation
Other_KIS_UHMK1_ST	P16949	STMN1	Q8TAS1	UHMK1	S25	E30K	30	Missense	distal	5	no	2.925	2.989	EPSD	ICGC	1.522	Up-regulation
Other_KIS_UHMK1_ST	P16949	STMN1	Q8TAS1	UHMK1	S25	E30Q	30	Missense	distal	5	no	2.925	2.934	EPSD	ICGC;COSMIC	1.522	Up-regulation
Other_KIS_UHMK1_ST	P16949	STMN1	Q8TAS1	UHMK1	S25	S31P	31	Missense	distal	6	no	2.925	2.968	EPSD	ICGC;COSMIC	1.522	Up-regulation
Other_KIS_UHMK1_ST	P16949	STMN1	Q8TAS1	UHMK1	S38	S31P	31	Missense	distal	-7	no	4.392	4.406	PhosphoSitePlus	ICGC;COSMIC	1.522	Up-regulation
Other_IKK_IKBKE_ST	Q96FA3	PELI1	Q14164	IKBKE	S76	S70C	70	Missense	distal	-6	no	95.218	97.668	EPSD;PhosphoSitePlus	ICGC	71.554	Up-regulation
Other_IKK_IKBKE_ST	Q96FA3	PELI1	Q14164	IKBKE	S76	R83Q	83	Missense	distal	7	no	95.218	96.020	EPSD;PhosphoSitePlus	ICGC;COSMIC	71.554	Up-regulation
Other_IKK_IKBKE_ST	Q96FA3	PELI1	Q14164	IKBKE	S76	Q74K	74	Missense	proximal	-2	no	95.218	84.894	EPSD;PhosphoSitePlus	ICGC;COSMIC	71.554	Down-regulation
Other_IKK_IKBKE_ST	Q96FA3	PELI1	Q14164	IKBKE	S76	N71K	71	Missense	distal	-5	no	95.218	86.419	EPSD;PhosphoSitePlus	ICGC	71.554	Down-regulation
Other_IKK_IKBKE_ST	Q96FA3	PELI1	Q14164	IKBKE	S76	H75Y	75	Missense	proximal	-1	no	95.218	97.587	EPSD;PhosphoSitePlus	ICGC;COSMIC	71.554	Up-regulation
Other_IKK_IKBKE_ST	Q96FA3	PELI1	Q14164	IKBKE	T80	R83Q	83	Missense	distal	3	no	95.218	93.587	PhosphoSitePlus;EPSD	ICGC;COSMIC	71.554	Down-regulation
Other_IKK_IKBKE_ST	Q96FA3	PELI1	Q14164	IKBKE	T80	Q74K	74	Missense	distal	-6	no	95.218	95.265	PhosphoSitePlus;EPSD	ICGC;COSMIC	71.554	Up-regulation
Other_IKK_IKBKE_ST	Q96FA3	PELI1	Q14164	IKBKE	T80	H75Y	75	Missense	distal	-5	no	95.218	95.599	PhosphoSitePlus;EPSD	ICGC;COSMIC	71.554	Up-regulation
Other_IKK_IKBKE_ST	Q96FA3	PELI1	Q14164	IKBKE	S125	T127A	127	Missense	proximal	2	no	73.691	69.756	EPSD	ICGC;COSMIC	71.554	Loss
Other_IKK_IKBKE_ST	Q96FA3	PELI1	Q14164	IKBKE	S129	T127A	127	Missense	proximal	-2	no	79.238	75.912	EPSD	ICGC;COSMIC	71.554	Down-regulation
Other_IKK_IKBKE_ST	Q96FA3	PELI1	Q14164	IKBKE	T288	N287D	287	Missense	proximal	-1	no	97.303	98.508	EPSD;PhosphoSitePlus	ICGC;COSMIC	71.554	Up-regulation
Other_IKK_IKBKE_ST	Q96FA3	PELI1	Q14164	IKBKE	S293	N287D	287	Missense	distal	-6	no	100.743	101.474	EPSD;PhosphoSitePlus	ICGC;COSMIC	71.554	Up-regulation
Other_IKK_IKBKE_ST	O95644	NFATC1	Q14164	IKBKE	S117	S124L	124	Missense	distal	7	no	97.976	98.759	EPSD;PhosphoSitePlus	ICGC;COSMIC	71.554	Up-regulation
Other_IKK_IKBKE_ST	O95644	NFATC1	Q14164	IKBKE	S117	R119H	119	Missense	proximal	2	no	97.976	93.123	EPSD;PhosphoSitePlus	ICGC;COSMIC	71.554	Down-regulation
Other_IKK_IKBKE_ST	O95644	NFATC1	Q14164	IKBKE	S117	E121K	121	Missense	distal	4	no	97.976	104.451	EPSD;PhosphoSitePlus	ICGC;COSMIC	71.554	Up-regulation
Other_IKK_IKBKE_ST	O95644	NFATC1	Q14164	IKBKE	S151	T154M	154	Missense	distal	3	no	95.414	94.577	EPSD;PhosphoSitePlus	ICGC;COSMIC;CCLE	71.554	Down-regulation
Other_IKK_IKBKE_ST	O95644	NFATC1	Q14164	IKBKE	S151	S151P	151	Missense	central	0	yes	95.414	0.000	EPSD;PhosphoSitePlus	ICGC;COSMIC	71.554	Loss
Other_IKK_IKBKE_ST	O95644	NFATC1	Q14164	IKBKE	S151	S158R	158	Missense	distal	7	no	95.414	94.891	EPSD;PhosphoSitePlus	ICGC;COSMIC	71.554	Down-regulation
Other_IKK_IKBKE_ST	O95644	NFATC1	Q14164	IKBKE	S151	S151C	151	Missense	central	0	yes	95.414	0.000	EPSD;PhosphoSitePlus	ICGC;COSMIC	71.554	Loss
Other_IKK_IKBKE_ST	O95644	NFATC1	Q14164	IKBKE	S151	R150L	150	Missense	proximal	-1	no	95.414	89.651	EPSD;PhosphoSitePlus	ICGC	71.554	Down-regulation
Other_IKK_IKBKE_ST	O95644	NFATC1	Q14164	IKBKE	S151	A155S	155	Missense	distal	4	no	95.414	99.324	EPSD;PhosphoSitePlus	ICGC	71.554	Up-regulation
Other_IKK_IKBKE_ST	O95644	NFATC1	Q14164	IKBKE	S151	P152L	152	Missense	proximal	1	no	95.414	98.796	EPSD;PhosphoSitePlus	ICGC;COSMIC	71.554	Up-regulation
Other_IKK_IKBKE_ST	O95644	NFATC1	Q14164	IKBKE	S151	P146S	146	Missense	distal	-5	no	95.414	91.701	EPSD;PhosphoSitePlus	ICGC;COSMIC	71.554	Down-regulation
Other_IKK_IKBKE_ST	O95644	NFATC1	Q14164	IKBKE	S151	V144I	144	Missense	distal	-7	no	95.414	97.977	EPSD;PhosphoSitePlus	ICGC;COSMIC	71.554	Up-regulation
Other_IKK_IKBKE_ST	O95644	NFATC1	Q14164	IKBKE	S151	T156M	156	Missense	distal	5	no	95.414	95.145	EPSD;PhosphoSitePlus	ICGC;COSMIC	71.554	Down-regulation
Other_IKK_IKBKE_ST	O95644	NFATC1	Q14164	IKBKE	S151	R150W	150	Missense	proximal	-1	no	95.414	85.876	EPSD;PhosphoSitePlus	ICGC	71.554	Down-regulation
Other_IKK_IKBKE_ST	O95644	NFATC1	Q14164	IKBKE	S158	T156M	156	Missense	proximal	-2	no	62.506	71.872	EPSD	ICGC;COSMIC	71.554	Gain
Other_IKK_IKBKE_ST	O95644	NFATC1	Q14164	IKBKE	S161	T154M	154	Missense	distal	-7	no	97.923	98.115	EPSD;PhosphoSitePlus	ICGC;COSMIC;CCLE	71.554	Up-regulation
Other_IKK_IKBKE_ST	O95644	NFATC1	Q14164	IKBKE	S161	E163K	163	Missense	proximal	2	no	97.923	96.332	EPSD;PhosphoSitePlus	ICGC;COSMIC	71.554	Down-regulation
Other_IKK_IKBKE_ST	O95644	NFATC1	Q14164	IKBKE	S161	S158R	158	Missense	distal	-3	no	97.923	98.644	EPSD;PhosphoSitePlus	ICGC;COSMIC	71.554	Up-regulation
Other_IKK_IKBKE_ST	O95644	NFATC1	Q14164	IKBKE	S161	A155S	155	Missense	distal	-6	no	97.923	95.944	EPSD;PhosphoSitePlus	ICGC	71.554	Down-regulation
Other_IKK_IKBKE_ST	O95644	NFATC1	Q14164	IKBKE	S161	D167Y	167	Missense	distal	6	no	97.923	94.955	EPSD;PhosphoSitePlus	ICGC;COSMIC	71.554	Down-regulation
Other_IKK_IKBKE_ST	O95644	NFATC1	Q14164	IKBKE	S161	T156M	156	Missense	distal	-5	no	97.923	87.986	EPSD;PhosphoSitePlus	ICGC;COSMIC	71.554	Down-regulation
Other_IKK_IKBKE_ST	O95644	NFATC1	Q14164	IKBKE	S233	G232C	232	Missense	proximal	-1	no	81.204	80.665	EPSD	ICGC;COSMIC	71.554	Down-regulation
Other_IKK_IKBKE_ST	O95644	NFATC1	Q14164	IKBKE	S233	P234L	234	Missense	proximal	1	no	81.204	84.586	EPSD	ICGC;COSMIC	71.554	Up-regulation
Other_IKK_IKBKE_ST	O95644	NFATC1	Q14164	IKBKE	S241	A244T	244	Missense	distal	3	no	79.048	81.664	EPSD	ICGC;COSMIC	71.554	Up-regulation
Other_IKK_IKBKE_ST	O95644	NFATC1	Q14164	IKBKE	S241	V246L	246	Missense	distal	5	no	79.048	79.068	EPSD	ICGC;COSMIC	71.554	Up-regulation
Other_IKK_IKBKE_ST	O95644	NFATC1	Q14164	IKBKE	S241	P242S	242	Missense	proximal	1	no	79.048	75.400	EPSD	ICGC;COSMIC	71.554	Down-regulation
Other_IKK_IKBKE_ST	O95644	NFATC1	Q14164	IKBKE	S241	V246I	246	Missense	distal	5	no	79.048	79.514	EPSD	ICGC;COSMIC	71.554	Up-regulation
Other_IKK_IKBKE_ST	O95644	NFATC1	Q14164	IKBKE	S241	P242L	242	Missense	proximal	1	no	79.048	82.430	EPSD	ICGC;COSMIC	71.554	Up-regulation
Other_IKK_IKBKE_ST	O95644	NFATC1	Q14164	IKBKE	S241	P234L	234	Missense	distal	-7	no	79.048	79.505	EPSD	ICGC;COSMIC	71.554	Up-regulation
Other_IKK_IKBKE_ST	O95644	NFATC1	Q14164	IKBKE	S245	A244T	244	Missense	proximal	-1	no	68.583	71.812	EPSD	ICGC;COSMIC	71.554	Gain
Other_IKK_IKBKE_ST	O95644	NFATC1	Q14164	IKBKE	S245	V246L	246	Missense	proximal	1	no	68.583	76.991	EPSD	ICGC;COSMIC	71.554	Gain
Other_IKK_IKBKE_ST	O95644	NFATC1	Q14164	IKBKE	S269	R273L	273	Missense	distal	4	no	82.411	74.074	EPSD	ICGC;COSMIC	71.554	Down-regulation
Other_IKK_IKBKE_ST	O95644	NFATC1	Q14164	IKBKE	S269	P262L	262	Missense	distal	-7	no	82.411	82.868	EPSD	ICGC;COSMIC	71.554	Up-regulation
Other_IKK_IKBKE_ST	O95644	NFATC1	Q14164	IKBKE	S269	G272V	272	Missense	distal	3	no	82.411	82.271	EPSD	ICGC;COSMIC	71.554	Down-regulation
Other_IKK_IKBKE_ST	O95644	NFATC1	Q14164	IKBKE	S269	P275S	275	Missense	distal	6	no	82.411	83.612	EPSD	ICGC	71.554	Up-regulation
Other_IKK_IKBKE_ST	O95644	NFATC1	Q14164	IKBKE	S269	P276A	276	Missense	distal	7	no	82.411	82.314	EPSD	ICGC;COSMIC	71.554	Down-regulation
Other_IKK_IKBKE_ST	O95644	NFATC1	Q14164	IKBKE	S269	R273Q	273	Missense	distal	4	no	82.411	76.950	EPSD	ICGC	71.554	Down-regulation
Other_IKK_IKBKE_ST	O95644	NFATC1	Q14164	IKBKE	S278	H281D	281	Missense	distal	3	no	70.673	72.634	EPSD	ICGC;COSMIC	71.554	Gain
Other_IKK_IKBKE_ST	O95644	NFATC1	Q14164	IKBKE	S278	P275S	275	Missense	distal	-3	no	70.673	72.340	EPSD	ICGC	71.554	Gain
Other_IKK_IKBKE_ST	O95644	NFATC1	Q14164	IKBKE	S278	H280Y	280	Missense	proximal	2	no	70.673	71.988	EPSD	ICGC;COSMIC	71.554	Gain
Other_IKK_IKBKE_ST	O95644	NFATC1	Q14164	IKBKE	S282	H281D	281	Missense	proximal	-1	no	68.061	71.957	EPSD	ICGC;COSMIC	71.554	Gain
Other_IKK_IKBKE_ST	O95644	NFATC1	Q14164	IKBKE	S324	D322Y	322	Missense	proximal	-2	no	96.624	84.065	PhosphoSitePlus;EPSD	ICGC;COSMIC	71.554	Down-regulation
Other_IKK_IKBKE_ST	O95644	NFATC1	Q14164	IKBKE	S359	P362L	362	Missense	distal	3	no	78.484	77.797	EPSD	ICGC;COSMIC	71.554	Down-regulation
Other_IKK_IKBKE_ST	O95644	NFATC1	Q14164	IKBKE	S359	G354E	354	Missense	distal	-5	no	78.484	82.690	EPSD	ICGC;COSMIC	71.554	Up-regulation
Other_IKK_IKBKE_ST	O95644	NFATC1	Q14164	IKBKE	S359	P361L	361	Missense	proximal	2	no	78.484	76.881	EPSD	ICGC	71.554	Down-regulation
Other_IKK_IKBKE_ST	O95644	NFATC1	Q14164	IKBKE	S359	P363S	363	Missense	distal	4	no	78.484	86.315	EPSD	ICGC	71.554	Up-regulation
Other_IKK_IKBKE_ST	O95644	NFATC1	Q14164	IKBKE	S359	A364G	364	Missense	distal	5	no	78.484	79.395	EPSD	ICGC;COSMIC	71.554	Up-regulation
Other_IKK_IKBKE_ST	O95644	NFATC1	Q14164	IKBKE	S526	E524D	524	Missense	proximal	-2	no	66.965	76.803	EPSD	ICGC;COSMIC	71.554	Gain
Other_IKK_IKBKE_ST	O95644	NFATC1	Q14164	IKBKE	S625	H619Q	619	Missense	distal	-6	no	72.474	70.204	EPSD	ICGC;COSMIC	71.554	Loss
Other_IKK_IKBKE_ST	O95644	NFATC1	Q14164	IKBKE	S625	V630L	630	Missense	distal	5	no	72.474	72.493	EPSD	ICGC;COSMIC	71.554	Up-regulation
Other_IKK_IKBKE_ST	O95644	NFATC1	Q14164	IKBKE	S625	N620I	620	Missense	distal	-5	no	72.474	68.867	EPSD	ICGC;COSMIC	71.554	Loss
Other_IKK_IKBKE_ST	O95644	NFATC1	Q14164	IKBKE	S625	G618C	618	Missense	distal	-7	no	72.474	73.539	EPSD	ICGC;COSMIC	71.554	Up-regulation
Other_IKK_IKBKE_ST	O95644	NFATC1	Q14164	IKBKE	S625	E631G	631	Missense	distal	6	no	72.474	75.007	EPSD	ICGC;COSMIC	71.554	Up-regulation
Other_IKK_IKBKE_ST	O95644	NFATC1	Q14164	IKBKE	S625	I628V	628	Missense	distal	3	no	72.474	73.281	EPSD	ICGC;COSMIC	71.554	Up-regulation
Other_IKK_IKBKE_ST	O95644	NFATC1	Q14164	IKBKE	S675	S670N	670	Missense	distal	-5	no	67.271	74.786	EPSD	ICGC;COSMIC	71.554	Gain
Other_IKK_IKBKE_ST	O95644	NFATC1	Q14164	IKBKE	S887	A890D	890	Missense	distal	3	no	81.472	84.571	EPSD	ICGC;COSMIC	71.554	Up-regulation
Other_IKK_IKBKE_ST	O95644	NFATC1	Q14164	IKBKE	S887	R893Q	893	Missense	distal	6	no	81.472	81.496	EPSD	ICGC	71.554	Up-regulation
Other_IKK_IKBKE_ST	O95644	NFATC1	Q14164	IKBKE	S887	R883C	883	Missense	distal	-4	no	81.472	74.856	EPSD	ICGC	71.554	Down-regulation
Other_IKK_IKBKE_ST	O95644	NFATC1	Q14164	IKBKE	S903	P910L	910	Missense	distal	7	no	72.002	72.013	EPSD	ICGC;COSMIC	71.554	Up-regulation
Other_IKK_IKBKE_ST	P25963	NFKBIA	Q14164	IKBKE	S32	R29S	29	Missense	distal	-3	no	107.210	106.490	EPSD;PhosphoSitePlus	ICGC	71.554	Down-regulation
Other_IKK_IKBKE_ST	P25963	NFKBIA	Q14164	IKBKE	S32	D31G	31	Missense	proximal	-1	no	107.210	103.527	EPSD;PhosphoSitePlus	ICGC;COSMIC	71.554	Down-regulation
Other_IKK_IKBKE_ST	P25963	NFKBIA	Q14164	IKBKE	S32	K38T	38	Missense	distal	6	no	107.210	109.015	EPSD;PhosphoSitePlus	ICGC	71.554	Up-regulation
Other_IKK_IKBKE_ST	P25963	NFKBIA	Q14164	IKBKE	S36	R29S	29	Missense	distal	-7	no	98.765	99.714	PhosphoSitePlus;EPSD	ICGC	71.554	Up-regulation
Other_IKK_IKBKE_ST	P25963	NFKBIA	Q14164	IKBKE	S36	D31G	31	Missense	distal	-5	no	98.765	93.199	PhosphoSitePlus;EPSD	ICGC;COSMIC	71.554	Down-regulation
Other_IKK_IKBKE_ST	P25963	NFKBIA	Q14164	IKBKE	S36	K38T	38	Missense	proximal	2	no	98.765	100.913	PhosphoSitePlus;EPSD	ICGC	71.554	Up-regulation
Other_IKK_IKBKE_ST	Q92985	IRF7	Q14164	IKBKE	S388	G381D	381	Missense	distal	-7	no	77.810	76.739	EPSD	ICGC;COSMIC	71.554	Down-regulation
Other_IKK_IKBKE_ST	Q92985	IRF7	Q14164	IKBKE	S388	C394Y	394	Missense	distal	6	no	77.810	82.172	EPSD	ICGC	71.554	Up-regulation
Other_IKK_IKBKE_ST	Q92985	IRF7	Q14164	IKBKE	S388	G385S	385	Missense	distal	-3	no	77.810	75.704	EPSD	ICGC;COSMIC	71.554	Down-regulation
Other_IKK_IKBKE_ST	Q92985	IRF7	Q14164	IKBKE	S471	S471F	471	Missense	central	0	yes	96.452	0.000	EPSD;PhosphoSitePlus	ICGC;COSMIC	71.554	Loss
Other_IKK_IKBKE_ST	Q92985	IRF7	Q14164	IKBKE	S471	S475N	475	Missense	distal	4	no	96.452	75.216	EPSD;PhosphoSitePlus	ICGC;COSMIC	71.554	Down-regulation
Other_IKK_IKBKE_ST	Q92985	IRF7	Q14164	IKBKE	S471	T465M	465	Missense	distal	-6	no	96.452	95.697	EPSD;PhosphoSitePlus	ICGC	71.554	Down-regulation
Other_IKK_IKBKE_ST	Q92985	IRF7	Q14164	IKBKE	S472	S471F	471	Missense	proximal	-1	no	103.179	100.527	EPSD;PhosphoSitePlus	ICGC;COSMIC	71.554	Down-regulation
Other_IKK_IKBKE_ST	Q92985	IRF7	Q14164	IKBKE	S472	S479R	479	Missense	distal	7	no	103.179	102.656	EPSD;PhosphoSitePlus	ICGC;COSMIC	71.554	Down-regulation
Other_IKK_IKBKE_ST	Q92985	IRF7	Q14164	IKBKE	S472	S475N	475	Missense	distal	3	no	103.179	105.391	EPSD;PhosphoSitePlus	ICGC;COSMIC	71.554	Up-regulation
Other_IKK_IKBKE_ST	Q92985	IRF7	Q14164	IKBKE	S472	T465M	465	Missense	distal	-7	no	103.179	103.371	EPSD;PhosphoSitePlus	ICGC	71.554	Up-regulation
Other_IKK_IKBKE_ST	Q92985	IRF7	Q14164	IKBKE	S477	S471F	471	Missense	distal	-6	no	94.759	95.015	PhosphoSitePlus;EPSD	ICGC;COSMIC	71.554	Up-regulation
Other_IKK_IKBKE_ST	Q92985	IRF7	Q14164	IKBKE	S477	C481R	481	Missense	distal	4	no	94.759	95.223	PhosphoSitePlus;EPSD	ICGC;COSMIC	71.554	Up-regulation
Other_IKK_IKBKE_ST	Q92985	IRF7	Q14164	IKBKE	S477	S479R	479	Missense	proximal	2	no	94.759	93.004	PhosphoSitePlus;EPSD	ICGC;COSMIC	71.554	Down-regulation
Other_IKK_IKBKE_ST	Q92985	IRF7	Q14164	IKBKE	S477	S475N	475	Missense	proximal	-2	no	94.759	90.379	PhosphoSitePlus;EPSD	ICGC;COSMIC	71.554	Down-regulation
Other_IKK_IKBKE_ST	Q92985	IRF7	Q14164	IKBKE	S479	C481R	481	Missense	proximal	2	no	85.941	86.528	EPSD;PhosphoSitePlus	ICGC;COSMIC	71.554	Up-regulation
Other_IKK_IKBKE_ST	Q92985	IRF7	Q14164	IKBKE	S479	S479R	479	Missense	central	0	yes	85.941	0.000	EPSD;PhosphoSitePlus	ICGC;COSMIC	71.554	Loss
Other_IKK_IKBKE_ST	Q92985	IRF7	Q14164	IKBKE	S479	S475N	475	Missense	distal	-4	no	85.941	86.678	EPSD;PhosphoSitePlus	ICGC;COSMIC	71.554	Up-regulation
Other_IKK_IKBKE_ST	Q92985	IRF7	Q14164	IKBKE	S479	A485T	485	Missense	distal	6	no	85.941	87.770	EPSD;PhosphoSitePlus	ICGC;COSMIC	71.554	Up-regulation
Other_IKK_IKBKE_ST	Q12933	TRAF2	Q14164	IKBKE	S102	E101G	101	Missense	proximal	-1	no	76.608	72.453	EPSD	ICGC;COSMIC	71.554	Down-regulation
Other_IKK_IKBKE_ST	Q12933	TRAF2	Q14164	IKBKE	S102	V106F	106	Missense	distal	4	no	76.608	56.900	EPSD	ICGC;COSMIC	71.554	Loss
Other_IKK_IKBKE_ST	Q12933	TRAF2	Q14164	IKBKE	S102	V106I	106	Missense	distal	4	no	76.608	48.856	EPSD	ICGC;COSMIC	71.554	Loss
Other_IKK_IKBKE_ST	O95786	DDX58	Q14164	IKBKE	S484	R488M	488	Missense	distal	4	no	69.153	77.884	EPSD	ICGC	71.554	Gain
Other_IKK_IKBKE_ST	P03372	ESR1	Q14164	IKBKE	S46	V51M	51	Missense	distal	5	no	76.917	78.176	EPSD	ICGC	71.554	Up-regulation
Other_IKK_IKBKE_ST	P03372	ESR1	Q14164	IKBKE	S46	D45E	45	Missense	proximal	-1	no	76.917	77.389	EPSD	ICGC;COSMIC	71.554	Up-regulation
Other_IKK_IKBKE_ST	P03372	ESR1	Q14164	IKBKE	S46	A50S	50	Missense	distal	4	no	76.917	80.826	EPSD	ICGC	71.554	Up-regulation
Other_IKK_IKBKE_ST	P03372	ESR1	Q14164	IKBKE	S104	P99S	99	Missense	distal	-5	no	81.324	77.610	EPSD	ICGC	71.554	Down-regulation
Other_IKK_IKBKE_ST	P03372	ESR1	Q14164	IKBKE	S104	S102N	102	Missense	proximal	-2	no	81.324	76.944	EPSD	ICGC;COSMIC	71.554	Down-regulation
Other_IKK_IKBKE_ST	P03372	ESR1	Q14164	IKBKE	S104	N101S	101	Missense	distal	-3	no	81.324	81.318	EPSD	ICGC;COSMIC	71.554	Down-regulation
Other_IKK_IKBKE_ST	P03372	ESR1	Q14164	IKBKE	S106	H112P	112	Missense	distal	6	no	66.771	72.955	EPSD	ICGC;COSMIC	71.554	Gain
Other_IKK_IKBKE_ST	P03372	ESR1	Q14164	IKBKE	S167	E163Q	163	Missense	distal	-4	no	96.639	93.491	PhosphoSitePlus	ICGC;COSMIC	71.554	Down-regulation
Other_IKK_IKBKE_ST	P03372	ESR1	Q14164	IKBKE	S305	K302T	302	Missense	distal	-3	no	71.296	73.170	EPSD	ICGC;COSMIC	71.554	Gain
Other_IKK_IKBKE_ST	P31749	AKT1	Q14164	IKBKE	T308	T305N	305	Missense	distal	-3	no	94.602	93.261	EPSD;PhosphoSitePlus	ICGC	71.554	Down-regulation
Other_IKK_IKBKE_ST	P31749	AKT1	Q14164	IKBKE	S378	T371K	371	Missense	distal	-7	no	77.927	78.405	EPSD	ICGC	71.554	Up-regulation
Other_IKK_IKBKE_ST	P31749	AKT1	Q14164	IKBKE	S378	T371M	371	Missense	distal	-7	no	77.927	78.119	EPSD	ICGC;COSMIC	71.554	Up-regulation
Other_IKK_IKBKE_ST	P31749	AKT1	Q14164	IKBKE	S473	Q471K	471	Missense	proximal	-2	no	82.406	72.082	PhosphoSitePlus;EPSD	ICGC	71.554	Down-regulation
Other_IKK_IKBKE_ST	P31749	AKT1	Q14164	IKBKE	S473	S477R	477	Missense	distal	4	no	82.406	71.120	PhosphoSitePlus;EPSD	ICGC	71.554	Loss
Other_IKK_IKBKE_ST	O14519	CDK2AP1	Q14164	IKBKE	S28	S28R	28	Missense	central	0	yes	79.825	0.000	EPSD	ICGC	71.554	Loss
Other_IKK_IKBKE_ST	O14519	CDK2AP1	Q14164	IKBKE	S28	S28N	28	Missense	central	0	yes	79.825	0.000	EPSD	ICGC	71.554	Loss
Other_IKK_IKBKE_ST	P98170	XIAP	Q14164	IKBKE	S38	N35D	35	Missense	distal	-3	no	76.505	78.630	EPSD	ICGC;COSMIC	71.554	Up-regulation
Other_IKK_IKBKE_ST	P98170	XIAP	Q14164	IKBKE	S38	V42F	42	Missense	distal	4	no	76.505	56.797	EPSD	ICGC	71.554	Loss
Other_IKK_IKBKE_ST	P98170	XIAP	Q14164	IKBKE	S38	S38C	38	Missense	central	0	yes	76.505	0.000	EPSD	ICGC	71.554	Loss
Other_IKK_IKBKE_ST	P98170	XIAP	Q14164	IKBKE	S40	N35D	35	Missense	distal	-5	no	76.542	75.757	EPSD	ICGC;COSMIC	71.554	Down-regulation
Other_IKK_IKBKE_ST	P98170	XIAP	Q14164	IKBKE	S40	V42F	42	Missense	proximal	2	no	76.542	70.193	EPSD	ICGC	71.554	Loss
Other_IKK_IKBKE_ST	P98170	XIAP	Q14164	IKBKE	S40	S38C	38	Missense	proximal	-2	no	76.542	55.624	EPSD	ICGC	71.554	Loss
Other_IKK_IKBKE_ST	P98170	XIAP	Q14164	IKBKE	S347	N340D	340	Missense	distal	-7	no	77.785	77.358	EPSD	ICGC	71.554	Down-regulation
Other_IKK_IKBKE_ST	P98170	XIAP	Q14164	IKBKE	S430	Q423P	423	Missense	distal	-7	no	98.479	98.347	PhosphoSitePlus	ICGC;COSMIC	71.554	Down-regulation
Other_IKK_IKBKE_ST	P46937	YAP1	Q14164	IKBKE	S103	T110S	110	Missense	distal	7	no	77.490	77.700	EPSD	ICGC;COSMIC	71.554	Up-regulation
Other_IKK_IKBKE_ST	P46937	YAP1	Q14164	IKBKE	S103	P99Q	99	Missense	distal	-4	no	77.490	77.866	EPSD	ICGC;COSMIC	71.554	Up-regulation
Other_IKK_IKBKE_ST	P46937	YAP1	Q14164	IKBKE	S149	T145N	145	Missense	distal	-4	no	78.232	78.040	EPSD	ICGC	71.554	Down-regulation
Other_IKK_IKBKE_ST	P46937	YAP1	Q14164	IKBKE	S164	D169N	169	Missense	distal	5	no	81.450	81.949	EPSD	ICGC;COSMIC	71.554	Up-regulation
Other_IKK_IKBKE_ST	P46937	YAP1	Q14164	IKBKE	S164	S163F	163	Missense	proximal	-1	no	81.450	78.798	EPSD	ICGC;COSMIC	71.554	Down-regulation
Other_IKK_IKBKE_ST	P46937	YAP1	Q14164	IKBKE	S164	V171A	171	Missense	distal	7	no	81.450	81.900	EPSD	ICGC;COSMIC	71.554	Up-regulation
Other_IKK_IKBKE_ST	P46937	YAP1	Q14164	IKBKE	S164	R161L	161	Missense	distal	-3	no	81.450	79.438	EPSD	ICGC	71.554	Down-regulation
Other_IKK_IKBKE_ST	P46937	YAP1	Q14164	IKBKE	S164	S164F	164	Missense	central	0	yes	81.450	0.000	EPSD	ICGC	71.554	Loss
Other_IKK_IKBKE_ST	P46937	YAP1	Q14164	IKBKE	S183	S184F	184	Missense	proximal	1	no	74.528	83.833	EPSD	ICGC;COSMIC	71.554	Up-regulation
Other_IKK_IKBKE_ST	P46937	YAP1	Q14164	IKBKE	S350	S350N	350	Missense	central	0	yes	76.931	0.000	EPSD	ICGC;COSMIC	71.554	Loss
Other_IKK_IKBKE_ST	P46937	YAP1	Q14164	IKBKE	S366	Q372K	372	Missense	distal	6	no	69.936	73.014	EPSD	ICGC;COSMIC	71.554	Gain
Other_IKK_IKBKE_ST	P46937	YAP1	Q14164	IKBKE	S406	L402P	402	Missense	distal	-4	no	75.332	75.571	EPSD	ICGC;COSMIC	71.554	Up-regulation
Other_IKK_IKBKE_ST	P46937	YAP1	Q14164	IKBKE	S406	V409F	409	Missense	distal	3	no	75.332	76.016	EPSD	ICGC	71.554	Up-regulation
Other_IKK_IKBKE_ST	P46937	YAP1	Q14164	IKBKE	S408	V409F	409	Missense	proximal	1	no	63.909	74.591	EPSD	ICGC	71.554	Gain
Other_IKK_IKBKE_ST	P46937	YAP1	Q14164	IKBKE	S419	E422K	422	Missense	distal	3	no	104.296	102.006	PhosphoSitePlus	ICGC;COSMIC	71.554	Down-regulation
Other_IKK_IKBKE_ST	P46937	YAP1	Q14164	IKBKE	S419	M423I	423	Missense	distal	4	no	104.296	75.633	PhosphoSitePlus	ICGC	71.554	Down-regulation
Other_IKK_IKBKE_ST	P46937	YAP1	Q14164	IKBKE	S432	N430T	430	Missense	proximal	-2	no	70.578	71.677	EPSD	ICGC;COSMIC	71.554	Gain
Other_IKK_IKBKE_ST	O00571	DDX3X	Q14164	IKBKE	S114	G117R	117	Missense	distal	3	no	77.913	78.996	EPSD	ICGC	71.554	Up-regulation
Other_IKK_IKBKE_ST	O00571	DDX3X	Q14164	IKBKE	S240	I238M	238	Missense	proximal	-2	no	66.288	78.052	EPSD	ICGC;COSMIC	71.554	Gain
Other_IKK_IKBKE_ST	O00571	DDX3X	Q14164	IKBKE	S269	L272S	272	Missense	distal	3	no	79.021	79.677	EPSD	ICGC;COSMIC	71.554	Up-regulation
Other_IKK_IKBKE_ST	O00571	DDX3X	Q14164	IKBKE	S412	S410F	410	Missense	proximal	-2	no	66.616	75.222	EPSD	ICGC;COSMIC	71.554	Gain
Other_IKK_IKBKE_ST	O00571	DDX3X	Q14164	IKBKE	T438	L443P	443	Missense	distal	5	no	74.598	74.129	EPSD	ICGC	71.554	Down-regulation
Other_IKK_IKBKE_ST	O00571	DDX3X	Q14164	IKBKE	T438	K440N	440	Missense	proximal	2	no	74.598	75.803	EPSD	ICGC;COSMIC	71.554	Up-regulation
Other_IKK_IKBKE_ST	O00571	DDX3X	Q14164	IKBKE	S489	F487L	487	Missense	proximal	-2	no	71.722	69.747	EPSD	ICGC;COSMIC;GDSC;CCLE	71.554	Loss
Other_IKK_IKBKE_ST	O00571	DDX3X	Q14164	IKBKE	S489	L495V	495	Missense	distal	6	no	71.722	73.921	EPSD	ICGC;COSMIC	71.554	Up-regulation
Other_IKK_IKBKE_ST	O00571	DDX3X	Q14164	IKBKE	S489	V496M	496	Missense	distal	7	no	71.722	71.307	EPSD	ICGC;COSMIC	71.554	Loss
Other_IKK_IKBKE_ST	O00571	DDX3X	Q14164	IKBKE	S489	R488S	488	Missense	proximal	-1	no	71.722	68.317	EPSD	ICGC;COSMIC	71.554	Loss
Other_IKK_IKBKE_ST	O00571	DDX3X	Q14164	IKBKE	S492	F487L	487	Missense	distal	-5	no	75.194	64.896	EPSD	ICGC;COSMIC;GDSC;CCLE	71.554	Loss
Other_IKK_IKBKE_ST	O00571	DDX3X	Q14164	IKBKE	S492	L495V	495	Missense	distal	3	no	75.194	76.277	EPSD	ICGC;COSMIC	71.554	Up-regulation
Other_IKK_IKBKE_ST	O00571	DDX3X	Q14164	IKBKE	S492	V496M	496	Missense	distal	4	no	75.194	76.106	EPSD	ICGC;COSMIC	71.554	Up-regulation
Other_IKK_IKBKE_ST	O00571	DDX3X	Q14164	IKBKE	S492	R488S	488	Missense	distal	-4	no	75.194	72.652	EPSD	ICGC;COSMIC	71.554	Down-regulation
Other_IKK_IKBKE_ST	O00571	DDX3X	Q14164	IKBKE	S520	V526G	526	Missense	distal	6	no	83.612	86.652	EPSD	ICGC	71.554	Up-regulation
Other_IKK_IKBKE_ST	O00571	DDX3X	Q14164	IKBKE	S520	Y525C	525	Missense	distal	5	no	83.612	81.138	EPSD	ICGC;COSMIC	71.554	Down-regulation
Other_IKK_IKBKE_ST	O00571	DDX3X	Q14164	IKBKE	S520	H527Y	527	Missense	distal	7	no	83.612	82.511	EPSD	ICGC;COSMIC	71.554	Down-regulation
Other_IKK_IKBKE_ST	O00571	DDX3X	Q14164	IKBKE	S610	G607C	607	Missense	distal	-3	no	72.289	69.498	EPSD	ICGC;COSMIC	71.554	Loss
Other_IKK_IKBKE_ST	O00571	DDX3X	Q14164	IKBKE	S620	G627V	627	Missense	distal	7	no	73.395	72.623	EPSD	ICGC;COSMIC	71.554	Down-regulation
Other_IKK_IKBKE_ST	O00571	DDX3X	Q14164	IKBKE	S630	G627V	627	Missense	distal	-3	no	79.620	77.482	EPSD	ICGC;COSMIC	71.554	Down-regulation
Other_IKK_IKBKE_ST	O00571	DDX3X	Q14164	IKBKE	S630	R632I	632	Missense	proximal	2	no	79.620	71.934	EPSD	ICGC;COSMIC	71.554	Down-regulation
Other_IKK_IKBKE_ST	O00571	DDX3X	Q14164	IKBKE	S631	G627V	627	Missense	distal	-4	no	78.417	78.726	EPSD	ICGC;COSMIC	71.554	Up-regulation
Other_IKK_IKBKE_ST	O00571	DDX3X	Q14164	IKBKE	S631	R632I	632	Missense	proximal	1	no	78.417	84.596	EPSD	ICGC;COSMIC	71.554	Up-regulation
Other_IKK_IKBKE_ST	Q04206	RELA	Q14164	IKBKE	S45	G48S	48	Missense	distal	3	no	73.237	72.670	EPSD	ICGC;COSMIC	71.554	Down-regulation
Other_IKK_IKBKE_ST	Q04206	RELA	Q14164	IKBKE	S45	R41H	41	Missense	distal	-4	no	73.237	67.320	EPSD	ICGC;COSMIC	71.554	Loss
Other_IKK_IKBKE_ST	Q04206	RELA	Q14164	IKBKE	S238	R236Q	236	Missense	proximal	-2	no	56.022	76.560	EPSD	ICGC;COSMIC	71.554	Gain
Other_IKK_IKBKE_ST	Q04206	RELA	Q14164	IKBKE	S311	P317H	317	Missense	distal	6	no	80.995	74.810	EPSD	ICGC;COSMIC	71.554	Down-regulation
Other_IKK_IKBKE_ST	Q04206	RELA	Q14164	IKBKE	S311	S311G	311	Missense	central	0	yes	80.995	0.000	EPSD	ICGC;COSMIC	71.554	Loss
Other_IKK_IKBKE_ST	Q04206	RELA	Q14164	IKBKE	S468	D470E	470	Missense	proximal	2	no	95.113	100.039	EPSD;PhosphoSitePlus	ICGC	71.554	Up-regulation
Other_IKK_IKBKE_ST	Q04206	RELA	Q14164	IKBKE	S536	A538V	538	Missense	proximal	2	no	85.327	89.845	PhosphoSitePlus;EPSD	ICGC;COSMIC	71.554	Up-regulation
Other_IKK_IKBKE_ST	Q14164	IKBKE	Q14164	IKBKE	S172	D166N	166	Missense	distal	-6	no	100.814	100.083	EPSD	ICGC;COSMIC	71.554	Down-regulation
Other_IKK_IKBKE_ST	Q14164	IKBKE	Q14164	IKBKE	S172	E177K	177	Missense	distal	5	no	100.814	102.140	EPSD	ICGC;COSMIC	71.554	Up-regulation
Other_IKK_IKBKE_ST	Q14164	IKBKE	Q14164	IKBKE	S172	Y179C	179	Missense	distal	7	no	100.814	101.401	EPSD	ICGC;COSMIC	71.554	Up-regulation
Other_IKK_IKBKE_ST	Q14164	IKBKE	Q14164	IKBKE	S172	D167Y	167	Missense	distal	-5	no	100.814	95.939	EPSD	ICGC	71.554	Down-regulation
Other_IKK_IKBKE_ST	Q14164	IKBKE	Q14164	IKBKE	T474	R476S	476	Missense	proximal	2	no	75.814	77.569	EPSD	ICGC	71.554	Up-regulation
Other_IKK_IKBKE_ST	Q14164	IKBKE	Q14164	IKBKE	S479	R476S	476	Missense	distal	-3	no	90.469	89.749	EPSD	ICGC	71.554	Down-regulation
Other_IKK_IKBKE_ST	Q14164	IKBKE	Q14164	IKBKE	S519	R525Q	525	Missense	distal	6	no	80.018	80.042	EPSD	ICGC;COSMIC;GDSC;CCLE	71.554	Up-regulation
Other_IKK_IKBKE_ST	Q14164	IKBKE	Q14164	IKBKE	S519	E526D	526	Missense	distal	7	no	80.018	80.350	EPSD	ICGC	71.554	Up-regulation
Other_IKK_IKBKE_ST	Q14164	IKBKE	Q14164	IKBKE	S519	E515D	515	Missense	distal	-4	no	80.018	78.163	EPSD	ICGC;COSMIC	71.554	Down-regulation
Other_IKK_IKBKE_ST	Q14164	IKBKE	Q14164	IKBKE	S522	R525Q	525	Missense	distal	3	no	90.537	88.906	EPSD	ICGC;COSMIC;GDSC;CCLE	71.554	Down-regulation
Other_IKK_IKBKE_ST	Q14164	IKBKE	Q14164	IKBKE	S522	E526D	526	Missense	distal	4	no	90.537	87.225	EPSD	ICGC	71.554	Down-regulation
Other_IKK_IKBKE_ST	Q14164	IKBKE	Q14164	IKBKE	S522	E515D	515	Missense	distal	-7	no	90.537	90.979	EPSD	ICGC;COSMIC	71.554	Up-regulation
Other_IKK_IKBKE_ST	O43524	FOXO3	Q14164	IKBKE	S26	S26C	26	Missense	central	0	yes	72.410	0.000	EPSD	ICGC;COSMIC	71.554	Loss
Other_IKK_IKBKE_ST	O43524	FOXO3	Q14164	IKBKE	S257	K262T	262	Missense	distal	5	no	76.074	75.115	EPSD	ICGC	71.554	Down-regulation
Other_IKK_IKBKE_ST	O43524	FOXO3	Q14164	IKBKE	T313	A317T	317	Missense	distal	4	no	78.900	81.652	EPSD	ICGC;COSMIC	71.554	Up-regulation
Other_IKK_IKBKE_ST	O43524	FOXO3	Q14164	IKBKE	S425	G424S	424	Missense	proximal	-1	no	79.149	82.287	EPSD	ICGC;COSMIC	71.554	Up-regulation
Other_IKK_IKBKE_ST	O43524	FOXO3	Q14164	IKBKE	S425	G420S	420	Missense	distal	-5	no	79.149	77.986	EPSD	ICGC;COSMIC	71.554	Down-regulation
Other_IKK_IKBKE_ST	O43524	FOXO3	Q14164	IKBKE	S425	S429Y	429	Missense	distal	4	no	79.149	67.846	EPSD	ICGC;COSMIC	71.554	Loss
Other_IKK_IKBKE_ST	O43524	FOXO3	Q14164	IKBKE	S429	G424S	424	Missense	distal	-5	no	74.376	73.213	EPSD	ICGC;COSMIC	71.554	Down-regulation
Other_IKK_IKBKE_ST	O43524	FOXO3	Q14164	IKBKE	S429	S429Y	429	Missense	central	0	yes	74.376	0.000	EPSD	ICGC;COSMIC	71.554	Loss
Other_IKK_IKBKE_ST	O43524	FOXO3	Q14164	IKBKE	S432	S429Y	429	Missense	distal	-3	no	74.413	71.990	EPSD	ICGC;COSMIC	71.554	Down-regulation
Other_IKK_IKBKE_ST	O43524	FOXO3	Q14164	IKBKE	S438	N441K	441	Missense	distal	3	no	78.933	76.838	EPSD	ICGC	71.554	Down-regulation
Other_IKK_IKBKE_ST	O43524	FOXO3	Q14164	IKBKE	S438	S442F	442	Missense	distal	4	no	78.933	55.759	EPSD	ICGC;COSMIC	71.554	Loss
Other_IKK_IKBKE_ST	O43524	FOXO3	Q14164	IKBKE	S442	N441K	441	Missense	proximal	-1	no	81.488	78.599	EPSD	ICGC	71.554	Down-regulation
Other_IKK_IKBKE_ST	O43524	FOXO3	Q14164	IKBKE	S442	S442F	442	Missense	central	0	yes	81.488	0.000	EPSD	ICGC;COSMIC	71.554	Loss
Other_IKK_IKBKE_ST	O43524	FOXO3	Q14164	IKBKE	S644	G637V	637	Missense	distal	-7	no	92.654	91.430	PhosphoSitePlus	ICGC	71.554	Down-regulation
Other_IKK_IKBKE_ST	P49840	GSK3A	Q14164	IKBKE	S129	V133M	133	Missense	distal	4	no	80.784	81.696	EPSD	ICGC;COSMIC;GDSC;CCLE	71.554	Up-regulation
Other_IKK_IKBKE_ST	P49840	GSK3A	Q14164	IKBKE	S129	G128D	128	Missense	proximal	-1	no	80.784	84.467	EPSD	ICGC;COSMIC	71.554	Up-regulation
Other_IKK_IKBKE_ST	P49840	GSK3A	Q14164	IKBKE	S129	G131E	131	Missense	proximal	2	no	80.784	82.487	EPSD	ICGC	71.554	Up-regulation
Other_IKK_IKBKE_ST	P49840	GSK3A	Q14164	IKBKE	S401	H400Q	400	Missense	proximal	-1	no	78.685	78.862	EPSD	ICGC;COSMIC	71.554	Up-regulation
Other_IKK_IKBKE_ST	Q9UNN5	FAF1	Q14164	IKBKE	S289	D292N	292	Missense	distal	3	no	72.465	73.323	EPSD	ICGC;COSMIC	71.554	Up-regulation
Other_IKK_IKBKE_ST	Q9UNN5	FAF1	Q14164	IKBKE	S289	D284A	284	Missense	distal	-5	no	72.465	61.587	EPSD	ICGC;COSMIC	71.554	Loss
Other_IKK_IKBKE_ST	Q9UNN5	FAF1	Q14164	IKBKE	S289	D284N	284	Missense	distal	-5	no	72.465	73.250	EPSD	ICGC	71.554	Up-regulation
Other_IKK_IKBKE_ST	Q9UNN5	FAF1	Q14164	IKBKE	S518	Q511K	511	Missense	distal	-7	no	71.549	71.737	EPSD	ICGC	71.554	Gain
Other_IKK_IKBKE_ST	Q9UNN5	FAF1	Q14164	IKBKE	S518	A514D	514	Missense	distal	-4	no	71.549	74.135	EPSD	ICGC	71.554	Gain
CMGC_MAPK_p38_MAPK12_ST	P15172	MYOD1	P53778	MAPK12	S201	R203L	203	Missense	proximal	2	no	132.509	131.920	PhosphoSitePlus;EPSD	ICGC;COSMIC	112.929	Down-regulation
CMGC_MAPK_p38_MAPK12_ST	P15172	MYOD1	P53778	MAPK12	S201	P202Q	202	Missense	proximal	1	no	132.509	-65.499	PhosphoSitePlus;EPSD	ICGC;COSMIC	112.929	Loss
CMGC_MAPK_p38_MAPK12_ST	P15172	MYOD1	P53778	MAPK12	S201	C206R	206	Missense	distal	5	no	132.509	133.318	PhosphoSitePlus;EPSD	ICGC;GDSC;CCLE	112.929	Up-regulation
CMGC_MAPK_p38_MAPK12_ST	Q12959	DLG1	P53778	MAPK12	S89	S90P	90	Missense	proximal	1	no	54.829	125.314	EPSD	ICGC;COSMIC	112.929	Gain
CMGC_MAPK_p38_MAPK12_ST	Q12959	DLG1	P53778	MAPK12	S100	L101I	101	Missense	proximal	1	no	116.422	86.076	EPSD	ICGC;COSMIC	112.929	Loss
CMGC_MAPK_p38_MAPK12_ST	Q12959	DLG1	P53778	MAPK12	S100	S102R	102	Missense	proximal	2	no	116.422	115.731	EPSD	ICGC	112.929	Down-regulation
CMGC_MAPK_p38_MAPK12_ST	Q12959	DLG1	P53778	MAPK12	S102	L101I	101	Missense	proximal	-1	no	120.826	122.248	EPSD	ICGC;COSMIC	112.929	Up-regulation
CMGC_MAPK_p38_MAPK12_ST	Q12959	DLG1	P53778	MAPK12	S102	S102R	102	Missense	central	0	yes	120.826	0.000	EPSD	ICGC	112.929	Loss
CMGC_MAPK_p38_MAPK12_ST	Q12959	DLG1	P53778	MAPK12	S102	R109M	109	Missense	distal	7	no	120.826	120.789	EPSD	ICGC;COSMIC	112.929	Down-regulation
CMGC_MAPK_p38_MAPK12_ST	Q12959	DLG1	P53778	MAPK12	T115	P116T	116	Missense	proximal	1	no	119.323	-11.889	EPSD	ICGC	112.929	Loss
CMGC_MAPK_p38_MAPK12_ST	Q12959	DLG1	P53778	MAPK12	T115	Y110C	110	Missense	distal	-5	no	119.323	119.013	EPSD	ICGC;COSMIC	112.929	Down-regulation
CMGC_MAPK_p38_MAPK12_ST	Q12959	DLG1	P53778	MAPK12	T115	R109M	109	Missense	distal	-6	no	119.323	118.867	EPSD	ICGC;COSMIC	112.929	Down-regulation
CMGC_MAPK_p38_MAPK12_ST	Q12959	DLG1	P53778	MAPK12	S122	P116T	116	Missense	distal	-6	no	120.748	122.245	PhosphoSitePlus;EPSD	ICGC	112.929	Up-regulation
CMGC_MAPK_p38_MAPK12_ST	Q12959	DLG1	P53778	MAPK12	S158	T163K	163	Missense	distal	5	no	133.815	133.954	EPSD;PhosphoSitePlus	ICGC	112.929	Up-regulation
CMGC_MAPK_p38_MAPK12_ST	Q12959	DLG1	P53778	MAPK12	T209	T209K	209	Missense	central	0	yes	136.800	0.000	EPSD;PhosphoSitePlus	ICGC;COSMIC	112.929	Loss
CMGC_MAPK_p38_MAPK12_ST	Q12959	DLG1	P53778	MAPK12	S583	Y585H	585	Missense	proximal	2	no	118.139	117.374	EPSD	ICGC;COSMIC	112.929	Down-regulation
CMGC_MAPK_p38_MAPK12_ST	Q00613	HSF1	P53778	MAPK12	S230	P223L	223	Missense	distal	-7	no	113.821	115.869	EPSD	ICGC	112.929	Up-regulation
CMGC_MAPK_p38_MAPK12_ST	Q00613	HSF1	P53778	MAPK12	S237	P239L	239	Missense	proximal	2	no	117.218	116.321	EPSD	ICGC;CCLE	112.929	Down-regulation
CMGC_MAPK_p38_MAPK12_ST	Q00613	HSF1	P53778	MAPK12	S244	P239L	239	Missense	distal	-5	no	127.884	127.614	EPSD	ICGC;CCLE	112.929	Down-regulation
CMGC_MAPK_p38_MAPK12_ST	Q00613	HSF1	P53778	MAPK12	S275	A278T	278	Missense	distal	3	no	135.072	134.771	EPSD	ICGC	112.929	Down-regulation
CMGC_MAPK_p38_MAPK12_ST	Q00613	HSF1	P53778	MAPK12	S279	A278T	278	Missense	proximal	-1	no	130.024	129.831	EPSD	ICGC	112.929	Down-regulation
CMGC_MAPK_p38_MAPK12_ST	Q00613	HSF1	P53778	MAPK12	S419	S421L	421	Missense	proximal	2	no	129.769	128.489	EPSD	ICGC;COSMIC	112.929	Down-regulation
CMGC_MAPK_p38_MAPK12_ST	Q00613	HSF1	P53778	MAPK12	S419	S419G	419	Missense	central	0	yes	129.769	0.000	EPSD	ICGC;COSMIC	112.929	Loss
CMGC_MAPK_p38_MAPK12_ST	Q00613	HSF1	P53778	MAPK12	S444	A437S	437	Missense	distal	-7	no	122.921	123.065	EPSD	ICGC;COSMIC	112.929	Up-regulation
CMGC_MAPK_p38_MAPK12_ST	P35222	CTNNB1	P53778	MAPK12	S246	L252H	252	Missense	distal	6	no	128.327	128.274	EPSD	ICGC;COSMIC	112.929	Down-regulation
CMGC_MAPK_p38_MAPK12_ST	P35222	CTNNB1	P53778	MAPK12	T258	L252H	252	Missense	distal	-6	no	117.276	116.014	EPSD	ICGC;COSMIC	112.929	Down-regulation
CMGC_MAPK_p38_MAPK12_ST	P10636	MAPT	P53778	MAPK12	T111	D116E	116	Missense	distal	5	no	138.577	136.744	EPSD	ICGC;COSMIC	112.929	Down-regulation
CMGC_MAPK_p38_MAPK12_ST	P10636	MAPT	P53778	MAPK12	S228	P233H	233	Missense	distal	5	no	119.197	118.370	EPSD	ICGC;COSMIC	112.929	Down-regulation
CMGC_MAPK_p38_MAPK12_ST	P10636	MAPT	P53778	MAPK12	S228	S232F	232	Missense	distal	4	no	119.197	117.587	EPSD	ICGC	112.929	Down-regulation
CMGC_MAPK_p38_MAPK12_ST	P10636	MAPT	P53778	MAPK12	S228	D225N	225	Missense	distal	-3	no	119.197	118.724	EPSD	ICGC	112.929	Down-regulation
CMGC_MAPK_p38_MAPK12_ST	P10636	MAPT	P53778	MAPK12	S228	V224I	224	Missense	distal	-4	no	119.197	127.419	EPSD	ICGC;COSMIC	112.929	Up-regulation
CMGC_MAPK_p38_MAPK12_ST	P10636	MAPT	P53778	MAPK12	S232	P233H	233	Missense	proximal	1	no	127.513	-6.302	EPSD	ICGC;COSMIC	112.929	Loss
CMGC_MAPK_p38_MAPK12_ST	P10636	MAPT	P53778	MAPK12	S232	S232F	232	Missense	central	0	yes	127.513	0.000	EPSD	ICGC	112.929	Loss
CMGC_MAPK_p38_MAPK12_ST	P10636	MAPT	P53778	MAPK12	S232	D225N	225	Missense	distal	-7	no	127.513	128.124	EPSD	ICGC	112.929	Up-regulation
CMGC_MAPK_p38_MAPK12_ST	P10636	MAPT	P53778	MAPK12	S232	P239Q	239	Missense	distal	7	no	127.513	126.046	EPSD	ICGC;COSMIC	112.929	Down-regulation
CMGC_MAPK_p38_MAPK12_ST	P10636	MAPT	P53778	MAPK12	S238	P233H	233	Missense	distal	-5	no	124.422	124.261	EPSD	ICGC;COSMIC	112.929	Down-regulation
CMGC_MAPK_p38_MAPK12_ST	P10636	MAPT	P53778	MAPK12	S238	S232F	232	Missense	distal	-6	no	124.422	127.988	EPSD	ICGC	112.929	Up-regulation
CMGC_MAPK_p38_MAPK12_ST	P10636	MAPT	P53778	MAPK12	S238	P239Q	239	Missense	proximal	1	no	124.422	-73.586	EPSD	ICGC;COSMIC	112.929	Loss
CMGC_MAPK_p38_MAPK12_ST	P10636	MAPT	P53778	MAPK12	S428	S427F	427	Missense	proximal	-1	no	140.380	137.021	EPSD	ICGC	112.929	Down-regulation
CMGC_MAPK_p38_MAPK12_ST	P10636	MAPT	P53778	MAPK12	S438	Y441H	441	Missense	distal	3	no	130.470	130.156	EPSD	ICGC;COSMIC	112.929	Down-regulation
CMGC_MAPK_p38_MAPK12_ST	P10636	MAPT	P53778	MAPK12	S516	G521R	521	Missense	distal	5	no	144.771	143.934	EPSD	ICGC;COSMIC	112.929	Down-regulation
CMGC_MAPK_p38_MAPK12_ST	P10636	MAPT	P53778	MAPK12	S519	G521R	521	Missense	proximal	2	no	138.829	138.858	EPSD	ICGC;COSMIC	112.929	Up-regulation
CMGC_MAPK_p38_MAPK12_ST	P10636	MAPT	P53778	MAPK12	T522	G521R	521	Missense	proximal	-1	no	140.094	138.531	EPSD	ICGC;COSMIC	112.929	Down-regulation
CMGC_MAPK_p38_MAPK12_ST	P26045	PTPN3	P53778	MAPK12	S372	S372F	372	Missense	central	0	yes	127.394	0.000	EPSD	ICGC;COSMIC	112.929	Loss
CMGC_MAPK_p38_MAPK12_ST	P26045	PTPN3	P53778	MAPK12	T376	R380L	380	Missense	distal	4	no	131.251	131.396	EPSD	ICGC;COSMIC	112.929	Up-regulation
CMGC_MAPK_p38_MAPK12_ST	P26045	PTPN3	P53778	MAPK12	T376	S372F	372	Missense	distal	-4	no	131.251	120.112	EPSD	ICGC;COSMIC	112.929	Down-regulation
CMGC_MAPK_p38_MAPK12_ST	P26045	PTPN3	P53778	MAPK12	S381	R380L	380	Missense	proximal	-1	no	118.537	118.522	EPSD	ICGC;COSMIC	112.929	Down-regulation
CMGC_MAPK_p38_MAPK12_ST	P26045	PTPN3	P53778	MAPK12	S434	Q437K	437	Missense	distal	3	no	126.560	126.583	EPSD	ICGC;COSMIC	112.929	Up-regulation
CMGC_MAPK_p38_MAPK12_ST	P26045	PTPN3	P53778	MAPK12	S434	N432D	432	Missense	proximal	-2	no	126.560	129.787	EPSD	ICGC;COSMIC	112.929	Up-regulation
CMGC_MAPK_p38_MAPK12_ST	P07900	HSP90AA1	P53778	MAPK12	S63	D66Y	66	Missense	distal	3	no	115.703	115.081	EPSD	ICGC;COSMIC	112.929	Down-regulation
CMGC_MAPK_p38_MAPK12_ST	P07900	HSP90AA1	P53778	MAPK12	S63	T65K	65	Missense	proximal	2	no	115.703	115.922	EPSD	ICGC	112.929	Up-regulation
CMGC_MAPK_p38_MAPK12_ST	P07900	HSP90AA1	P53778	MAPK12	S72	D66Y	66	Missense	distal	-6	no	126.628	126.150	EPSD	ICGC;COSMIC	112.929	Down-regulation
CMGC_MAPK_p38_MAPK12_ST	P07900	HSP90AA1	P53778	MAPK12	S72	I78V	78	Missense	distal	6	no	126.628	125.789	EPSD	ICGC;COSMIC	112.929	Down-regulation
CMGC_MAPK_p38_MAPK12_ST	P07900	HSP90AA1	P53778	MAPK12	S72	T65K	65	Missense	distal	-7	no	126.628	126.137	EPSD	ICGC	112.929	Down-regulation
CMGC_MAPK_p38_MAPK12_ST	P07900	HSP90AA1	P53778	MAPK12	S72	E75V	75	Missense	distal	3	no	126.628	126.459	EPSD	ICGC;COSMIC	112.929	Down-regulation
CMGC_MAPK_p38_MAPK12_ST	P07900	HSP90AA1	P53778	MAPK12	T88	L89P	89	Missense	proximal	1	no	106.536	123.282	EPSD	ICGC;COSMIC	112.929	Gain
CMGC_MAPK_p38_MAPK12_ST	P07900	HSP90AA1	P53778	MAPK12	T94	G97E	97	Missense	distal	3	no	117.452	116.950	EPSD	ICGC;COSMIC	112.929	Down-regulation
CMGC_MAPK_p38_MAPK12_ST	P07900	HSP90AA1	P53778	MAPK12	T94	V92M	92	Missense	proximal	-2	no	117.452	117.512	EPSD	ICGC	112.929	Up-regulation
CMGC_MAPK_p38_MAPK12_ST	P07900	HSP90AA1	P53778	MAPK12	T94	G97R	97	Missense	distal	3	no	117.452	117.113	EPSD	ICGC;COSMIC	112.929	Down-regulation
CMGC_MAPK_p38_MAPK12_ST	P07900	HSP90AA1	P53778	MAPK12	T94	G95R	95	Missense	proximal	1	no	117.452	-51.913	EPSD	ICGC;COSMIC	112.929	Loss
CMGC_MAPK_p38_MAPK12_ST	P07900	HSP90AA1	P53778	MAPK12	T94	M98I	98	Missense	distal	4	no	117.452	118.182	EPSD	ICGC;COSMIC	112.929	Up-regulation
CMGC_MAPK_p38_MAPK12_ST	P07900	HSP90AA1	P53778	MAPK12	T94	L89P	89	Missense	distal	-5	no	117.452	117.723	EPSD	ICGC;COSMIC	112.929	Up-regulation
CMGC_MAPK_p38_MAPK12_ST	P07900	HSP90AA1	P53778	MAPK12	T94	T94N	94	Missense	central	0	yes	117.452	0.000	EPSD	ICGC;COSMIC	112.929	Loss
CMGC_MAPK_p38_MAPK12_ST	P07900	HSP90AA1	P53778	MAPK12	S113	A117S	117	Missense	distal	4	no	116.026	115.804	EPSD	ICGC;COSMIC	112.929	Down-regulation
CMGC_MAPK_p38_MAPK12_ST	P07900	HSP90AA1	P53778	MAPK12	S315	G310R	310	Missense	distal	-5	no	114.144	113.947	EPSD	ICGC;COSMIC	112.929	Down-regulation
CMGC_MAPK_p38_MAPK12_ST	P07900	HSP90AA1	P53778	MAPK12	S315	D322N	322	Missense	distal	7	no	114.144	114.372	EPSD	ICGC;COSMIC	112.929	Up-regulation
CMGC_MAPK_p38_MAPK12_ST	P07900	HSP90AA1	P53778	MAPK12	S315	F312L	312	Missense	distal	-3	no	114.144	114.598	EPSD	ICGC;COSMIC	112.929	Up-regulation
CMGC_MAPK_p38_MAPK12_ST	P07900	HSP90AA1	P53778	MAPK12	S470	R464K	464	Missense	distal	-6	no	114.747	113.052	EPSD	ICGC	112.929	Down-regulation
CMGC_MAPK_p38_MAPK12_ST	P07900	HSP90AA1	P53778	MAPK12	S470	A469T	469	Missense	proximal	-1	no	114.747	114.553	EPSD	ICGC	112.929	Down-regulation
CMGC_MAPK_p38_MAPK12_ST	P07900	HSP90AA1	P53778	MAPK12	S470	L463S	463	Missense	distal	-7	no	114.747	112.439	EPSD	ICGC;COSMIC	112.929	Loss
CMGC_MAPK_p38_MAPK12_ST	P07900	HSP90AA1	P53778	MAPK12	T495	K499N	499	Missense	distal	4	no	117.784	117.895	EPSD	ICGC;COSMIC	112.929	Up-regulation
CMGC_MAPK_p38_MAPK12_ST	P07900	HSP90AA1	P53778	MAPK12	T495	T495K	495	Missense	central	0	yes	117.784	0.000	EPSD	ICGC	112.929	Loss
CMGC_MAPK_p38_MAPK12_ST	P07900	HSP90AA1	P53778	MAPK12	T495	D500N	500	Missense	distal	5	no	117.784	117.216	EPSD	ICGC;COSMIC	112.929	Down-regulation
CMGC_MAPK_p38_MAPK12_ST	P07900	HSP90AA1	P53778	MAPK12	T495	G496C	496	Missense	proximal	1	no	117.784	-56.063	EPSD	ICGC	112.929	Loss
CMGC_MAPK_p38_MAPK12_ST	P07900	HSP90AA1	P53778	MAPK12	T645	E651Q	651	Missense	distal	6	no	114.013	114.198	EPSD	ICGC;COSMIC	112.929	Up-regulation
CMGC_MAPK_p38_MAPK12_ST	P07900	HSP90AA1	P53778	MAPK12	T645	E651V	651	Missense	distal	6	no	114.013	114.153	EPSD	ICGC;COSMIC	112.929	Up-regulation
CMGC_MAPK_p38_MAPK12_ST	P07900	HSP90AA1	P53778	MAPK12	T645	S641C	641	Missense	distal	-4	no	114.013	105.284	EPSD	ICGC;COSMIC	112.929	Loss
CMGC_MAPK_p38_MAPK12_ST	P07900	HSP90AA1	P53778	MAPK12	T645	A650S	650	Missense	distal	5	no	114.013	114.942	EPSD	ICGC	112.929	Up-regulation
CMGC_MAPK_p38_MAPK12_ST	P07900	HSP90AA1	P53778	MAPK12	T645	E644D	644	Missense	proximal	-1	no	114.013	116.923	EPSD	ICGC;COSMIC	112.929	Up-regulation
CMGC_MAPK_p38_MAPK12_ST	P07900	HSP90AA1	P53778	MAPK12	T645	I642M	642	Missense	distal	-3	no	114.013	113.486	EPSD	ICGC;COSMIC	112.929	Down-regulation
CMGC_MAPK_p38_MAPK12_ST	P07900	HSP90AA1	P53778	MAPK12	T645	A650E	650	Missense	distal	5	no	114.013	112.988	EPSD	ICGC	112.929	Down-regulation
CMGC_MAPK_p38_MAPK12_ST	P07900	HSP90AA1	P53778	MAPK12	T645	A652V	652	Missense	distal	7	no	114.013	112.845	EPSD	ICGC	112.929	Loss
CMGC_MAPK_p38_MAPK12_ST	P30281	CCND3	P53778	MAPK12	S264	S259A	259	Missense	distal	-5	no	126.610	126.590	EPSD	ICGC;COSMIC	112.929	Down-regulation
CMGC_MAPK_p38_MAPK12_ST	P30281	CCND3	P53778	MAPK12	S264	A266E	266	Missense	proximal	2	no	126.610	125.594	EPSD	ICGC;COSMIC	112.929	Down-regulation
CMGC_MAPK_p38_MAPK12_ST	P30281	CCND3	P53778	MAPK12	S264	S262I	262	Missense	proximal	-2	no	126.610	126.814	EPSD	ICGC;COSMIC	112.929	Up-regulation
CMGC_MAPK_p38_MAPK12_ST	P30281	CCND3	P53778	MAPK12	S282	T283P	283	Missense	proximal	1	no	-12.053	119.159	EPSD	ICGC;COSMIC	112.929	Gain
CMGC_MAPK_p38_MAPK12_ST	P30281	CCND3	P53778	MAPK12	T283	A289D	289	Missense	distal	6	no	130.221	130.425	PhosphoSitePlus	ICGC	112.929	Up-regulation
CMGC_MAPK_p38_MAPK12_ST	P30281	CCND3	P53778	MAPK12	T283	I290K	290	Missense	distal	7	no	130.221	130.129	PhosphoSitePlus	ICGC;COSMIC;CCLE	112.929	Down-regulation
CMGC_MAPK_p38_MAPK12_ST	P30281	CCND3	P53778	MAPK12	T283	I290T	290	Missense	distal	7	no	130.221	129.538	PhosphoSitePlus	ICGC;COSMIC;CCLE	112.929	Down-regulation
CMGC_MAPK_p38_MAPK12_ST	P30281	CCND3	P53778	MAPK12	T283	T283P	283	Missense	central	0	yes	130.221	0.000	PhosphoSitePlus	ICGC;COSMIC	112.929	Loss
CMGC_MAPK_p38_MAPK12_ST	P30281	CCND3	P53778	MAPK12	T283	D286A	286	Missense	distal	3	no	130.221	129.744	PhosphoSitePlus	ICGC	112.929	Down-regulation
STE_STE7_MEK4_MAP2K4_ST	P45983	MAPK8	P45985	MAP2K4	T21	R25L	25	Missense	distal	4	no	0.006	0.005	EPSD	ICGC	0.006	Loss
STE_STE7_MEK4_MAP2K4_ST	P45983	MAPK8	P45985	MAP2K4	T178	G171C	171	Missense	distal	-7	no	0.005	0.006	EPSD	ICGC;COSMIC	0.006	Gain
STE_STE7_MEK4_MAP2K4_ST	P45983	MAPK8	P45985	MAP2K4	T183	R189P	189	Missense	distal	6	no	0.031	0.032	PhosphoSitePlus;EPSD	ICGC;COSMIC	0.006	Up-regulation
STE_STE7_MEK4_MAP2K4_ST	P45983	MAPK8	P45985	MAP2K4	T183	T183M	183	Missense	central	0	yes	0.031	0.000	PhosphoSitePlus;EPSD	ICGC;COSMIC	0.006	Loss
STE_STE7_MEK4_MAP2K4_ST	P45983	MAPK8	P45985	MAP2K4	T243	P246H	246	Missense	distal	3	no	0.005	0.006	EPSD	ICGC;COSMIC	0.006	Gain
STE_STE7_MEK4_MAP2K4_ST	P45984	MAPK9	P45985	MAP2K4	T183	V186M	186	Missense	distal	3	no	0.031	0.029	EPSD	ICGC	0.006	Down-regulation
STE_STE7_MEK4_MAP2K4_ST	P45984	MAPK9	P45985	MAP2K4	T409	E402K	402	Missense	distal	-7	no	0.007	0.006	EPSD	ICGC;COSMIC	0.006	Down-regulation
STE_STE7_MEK4_MAP2K4_ST	P45984	MAPK9	P45985	MAP2K4	T409	T409K	409	Missense	central	0	yes	0.007	0.000	EPSD	ICGC	0.006	Loss
STE_STE7_MEK4_MAP2K4_ST	P45984	MAPK9	P45985	MAP2K4	S412	D410E	410	Missense	proximal	-2	no	0.009	0.010	EPSD	ICGC	0.006	Up-regulation
STE_STE7_MEK4_MAP2K4_ST	P19793	RXRA	P45985	MAP2K4	T82	S88I	88	Missense	distal	6	no	0.006	0.005	EPSD	ICGC	0.006	Loss
STE_STE7_MEK4_MAP2K4_ST	P19793	RXRA	P45985	MAP2K4	S124	A128T	128	Missense	distal	4	no	0.005	0.006	EPSD	ICGC;COSMIC	0.006	Gain
STE_STE7_MEK4_MAP2K4_ST	P19793	RXRA	P45985	MAP2K4	S124	H122N	122	Missense	proximal	-2	no	0.005	0.006	EPSD	ICGC;COSMIC	0.006	Gain
STE_STE7_MEK4_MAP2K4_ST	P19793	RXRA	P45985	MAP2K4	S151	S151N	151	Missense	central	0	yes	0.006	0.000	EPSD	ICGC;COSMIC	0.006	Loss
AGC_PDK1_PDPK1_ST	Q9HBY8	SGK2	O15530	PDPK1	S64	C58F	58	Missense	distal	-6	no	6.464	6.549	EPSD	ICGC;COSMIC	3.516	Up-regulation
AGC_PDK1_PDPK1_ST	O15530	PDPK1	O15530	PDPK1	S92	S92F	92	Missense	central	0	yes	5.413	0.000	EPSD	ICGC	3.516	Loss
AGC_PDK1_PDPK1_ST	Q16512	PKN1	O15530	PDPK1	S112	P118S	118	Missense	distal	6	no	4.232	4.233	EPSD	ICGC;COSMIC	3.516	Up-regulation
AGC_PDK1_PDPK1_ST	Q16512	PKN1	O15530	PDPK1	T119	C120F	120	Missense	proximal	1	no	0.716	6.540	EPSD	ICGC	3.516	Gain
AGC_PDK1_PDPK1_ST	Q16512	PKN1	O15530	PDPK1	T123	V128M	128	Missense	distal	5	no	3.237	3.670	EPSD	ICGC;COSMIC	3.516	Gain
AGC_PDK1_PDPK1_ST	Q16512	PKN1	O15530	PDPK1	S205	P199L	199	Missense	distal	-6	no	4.302	4.391	EPSD	ICGC;COSMIC	3.516	Up-regulation
AGC_PDK1_PDPK1_ST	Q16512	PKN1	O15530	PDPK1	S205	A210D	210	Missense	distal	5	no	4.302	4.077	EPSD	ICGC	3.516	Down-regulation
AGC_PDK1_PDPK1_ST	Q16512	PKN1	O15530	PDPK1	S205	A210S	210	Missense	distal	5	no	4.302	4.726	EPSD	ICGC	3.516	Up-regulation
AGC_PDK1_PDPK1_ST	Q16512	PKN1	O15530	PDPK1	S205	V211L	211	Missense	distal	6	no	4.302	4.303	EPSD	ICGC	3.516	Up-regulation
AGC_PDK1_PDPK1_ST	Q16512	PKN1	O15530	PDPK1	S301	T302P	302	Missense	proximal	1	no	0.625	3.592	EPSD	ICGC;CCLE	3.516	Gain
AGC_PDK1_PDPK1_ST	Q16512	PKN1	O15530	PDPK1	T353	S356I	356	Missense	distal	3	no	6.038	5.626	EPSD	ICGC;COSMIC	3.516	Down-regulation
AGC_PDK1_PDPK1_ST	Q16512	PKN1	O15530	PDPK1	T353	G349R	349	Missense	distal	-4	no	6.038	6.068	EPSD	ICGC;COSMIC	3.516	Up-regulation
AGC_PDK1_PDPK1_ST	Q16512	PKN1	O15530	PDPK1	T353	G350R	350	Missense	distal	-3	no	6.038	6.778	EPSD	ICGC;COSMIC	3.516	Up-regulation
AGC_PDK1_PDPK1_ST	Q16512	PKN1	O15530	PDPK1	T353	G352E	352	Missense	proximal	-1	no	6.038	5.873	EPSD	ICGC;COSMIC	3.516	Down-regulation
AGC_PDK1_PDPK1_ST	Q16512	PKN1	O15530	PDPK1	S533	F532V	532	Missense	proximal	-1	no	4.154	4.638	EPSD	ICGC;COSMIC	3.516	Up-regulation
AGC_PDK1_PDPK1_ST	Q16512	PKN1	O15530	PDPK1	S533	G530C	530	Missense	distal	-3	no	4.154	4.028	EPSD	ICGC;COSMIC	3.516	Down-regulation
AGC_PDK1_PDPK1_ST	Q16512	PKN1	O15530	PDPK1	S533	T531I	531	Missense	proximal	-2	no	4.154	3.912	EPSD	ICGC;COSMIC	3.516	Down-regulation
AGC_PDK1_PDPK1_ST	Q16512	PKN1	O15530	PDPK1	S537	R543Q	543	Missense	distal	6	no	4.668	4.669	EPSD	ICGC;COSMIC	3.516	Up-regulation
AGC_PDK1_PDPK1_ST	Q16512	PKN1	O15530	PDPK1	S537	F532V	532	Missense	distal	-5	no	4.668	4.433	EPSD	ICGC;COSMIC	3.516	Down-regulation
AGC_PDK1_PDPK1_ST	Q16512	PKN1	O15530	PDPK1	S537	G530C	530	Missense	distal	-7	no	4.668	3.748	EPSD	ICGC;COSMIC	3.516	Down-regulation
AGC_PDK1_PDPK1_ST	Q16512	PKN1	O15530	PDPK1	S537	T531I	531	Missense	distal	-6	no	4.668	4.798	EPSD	ICGC;COSMIC	3.516	Up-regulation
AGC_PDK1_PDPK1_ST	Q16512	PKN1	O15530	PDPK1	S537	R543W	543	Missense	distal	6	no	4.668	4.670	EPSD	ICGC;COSMIC	3.516	Up-regulation
AGC_PDK1_PDPK1_ST	Q16512	PKN1	O15530	PDPK1	S561	T557I	557	Missense	distal	-4	no	4.280	4.443	EPSD	ICGC;COSMIC	3.516	Up-regulation
AGC_PDK1_PDPK1_ST	Q16512	PKN1	O15530	PDPK1	S561	R568W	568	Missense	distal	7	no	4.280	4.098	EPSD	ICGC;COSMIC	3.516	Down-regulation
AGC_PDK1_PDPK1_ST	Q16512	PKN1	O15530	PDPK1	S561	S567L	567	Missense	distal	6	no	4.280	4.281	EPSD	ICGC;COSMIC	3.516	Up-regulation
AGC_PDK1_PDPK1_ST	Q16512	PKN1	O15530	PDPK1	S562	D569G	569	Missense	distal	7	no	4.751	4.672	EPSD	ICGC;COSMIC	3.516	Down-regulation
AGC_PDK1_PDPK1_ST	Q16512	PKN1	O15530	PDPK1	S562	T557I	557	Missense	distal	-5	no	4.751	4.995	EPSD	ICGC;COSMIC	3.516	Up-regulation
AGC_PDK1_PDPK1_ST	Q16512	PKN1	O15530	PDPK1	S562	R568W	568	Missense	distal	6	no	4.751	4.753	EPSD	ICGC;COSMIC	3.516	Up-regulation
AGC_PDK1_PDPK1_ST	Q16512	PKN1	O15530	PDPK1	S562	S567L	567	Missense	distal	5	no	4.751	3.644	EPSD	ICGC;COSMIC	3.516	Down-regulation
AGC_PDK1_PDPK1_ST	Q16512	PKN1	O15530	PDPK1	S566	D569G	569	Missense	distal	3	no	3.532	3.741	EPSD	ICGC;COSMIC	3.516	Up-regulation
AGC_PDK1_PDPK1_ST	Q16512	PKN1	O15530	PDPK1	S566	R568W	568	Missense	proximal	2	no	3.532	3.446	EPSD	ICGC;COSMIC	3.516	Loss
AGC_PDK1_PDPK1_ST	Q16512	PKN1	O15530	PDPK1	S566	S567L	567	Missense	proximal	1	no	3.532	3.908	EPSD	ICGC;COSMIC	3.516	Up-regulation
AGC_PDK1_PDPK1_ST	Q16512	PKN1	O15530	PDPK1	S573	D569G	569	Missense	distal	-4	no	7.194	7.140	EPSD	ICGC;COSMIC	3.516	Down-regulation
AGC_PDK1_PDPK1_ST	Q16512	PKN1	O15530	PDPK1	S573	R568W	568	Missense	distal	-5	no	7.194	7.335	EPSD	ICGC;COSMIC	3.516	Up-regulation
AGC_PDK1_PDPK1_ST	Q16512	PKN1	O15530	PDPK1	S573	S579F	579	Missense	distal	6	no	7.194	7.196	EPSD	ICGC;COSMIC	3.516	Up-regulation
AGC_PDK1_PDPK1_ST	Q16512	PKN1	O15530	PDPK1	S573	S567L	567	Missense	distal	-6	no	7.194	7.285	EPSD	ICGC;COSMIC	3.516	Up-regulation
AGC_PDK1_PDPK1_ST	Q16512	PKN1	O15530	PDPK1	S575	D569G	569	Missense	distal	-6	no	4.264	4.190	EPSD	ICGC;COSMIC	3.516	Down-regulation
AGC_PDK1_PDPK1_ST	Q16512	PKN1	O15530	PDPK1	S575	R568W	568	Missense	distal	-7	no	4.264	3.490	EPSD	ICGC;COSMIC	3.516	Loss
AGC_PDK1_PDPK1_ST	Q16512	PKN1	O15530	PDPK1	S575	S579F	579	Missense	distal	4	no	4.264	2.735	EPSD	ICGC;COSMIC	3.516	Loss
AGC_PDK1_PDPK1_ST	Q16512	PKN1	O15530	PDPK1	S575	Q582H	582	Missense	distal	7	no	4.264	4.437	EPSD	ICGC	3.516	Up-regulation
AGC_PDK1_PDPK1_ST	Q16512	PKN1	O15530	PDPK1	S578	S579F	579	Missense	proximal	1	no	3.056	6.393	EPSD	ICGC;COSMIC	3.516	Gain
AGC_PDK1_PDPK1_ST	Q16512	PKN1	O15530	PDPK1	S579	S579F	579	Missense	central	0	yes	5.212	0.000	EPSD	ICGC;COSMIC	3.516	Loss
AGC_PDK1_PDPK1_ST	Q16512	PKN1	O15530	PDPK1	S579	Q582H	582	Missense	distal	3	no	5.212	5.199	EPSD	ICGC	3.516	Down-regulation
AGC_PDK1_PDPK1_ST	Q16512	PKN1	O15530	PDPK1	T596	S603I	603	Missense	distal	7	no	5.235	4.802	EPSD	ICGC;COSMIC	3.516	Down-regulation
AGC_PDK1_PDPK1_ST	Q16512	PKN1	O15530	PDPK1	T596	S591L	591	Missense	distal	-5	no	5.235	5.519	EPSD	ICGC;COSMIC	3.516	Up-regulation
AGC_PDK1_PDPK1_ST	Q16512	PKN1	O15530	PDPK1	T596	P590L	590	Missense	distal	-6	no	5.235	5.324	EPSD	ICGC	3.516	Up-regulation
AGC_PDK1_PDPK1_ST	Q16512	PKN1	O15530	PDPK1	S773	T778A	778	Missense	distal	5	no	4.118	3.648	PhosphoSitePlus;EPSD	ICGC;COSMIC	3.516	Down-regulation
AGC_PDK1_PDPK1_ST	Q16512	PKN1	O15530	PDPK1	S773	P779L	779	Missense	distal	6	no	4.118	4.119	PhosphoSitePlus;EPSD	ICGC;COSMIC	3.516	Up-regulation
AGC_PDK1_PDPK1_ST	Q16512	PKN1	O15530	PDPK1	S773	R771Q	771	Missense	proximal	-2	no	4.118	4.058	PhosphoSitePlus;EPSD	ICGC;COSMIC;CCLE	3.516	Down-regulation
AGC_PDK1_PDPK1_ST	Q16512	PKN1	O15530	PDPK1	S773	E780K	780	Missense	distal	7	no	4.118	4.077	PhosphoSitePlus;EPSD	ICGC;COSMIC	3.516	Down-regulation
AGC_PDK1_PDPK1_ST	Q16512	PKN1	O15530	PDPK1	S773	R771W	771	Missense	proximal	-2	no	4.118	4.011	PhosphoSitePlus;EPSD	ICGC	3.516	Down-regulation
AGC_PDK1_PDPK1_ST	Q16512	PKN1	O15530	PDPK1	T774	T778A	778	Missense	distal	4	no	10.248	9.759	EPSD;PhosphoSitePlus	ICGC;COSMIC	3.516	Down-regulation
AGC_PDK1_PDPK1_ST	Q16512	PKN1	O15530	PDPK1	T774	P779L	779	Missense	distal	5	no	10.248	9.253	EPSD;PhosphoSitePlus	ICGC;COSMIC	3.516	Down-regulation
AGC_PDK1_PDPK1_ST	Q16512	PKN1	O15530	PDPK1	T774	R771Q	771	Missense	distal	-3	no	10.248	9.513	EPSD;PhosphoSitePlus	ICGC;COSMIC;CCLE	3.516	Down-regulation
AGC_PDK1_PDPK1_ST	Q16512	PKN1	O15530	PDPK1	T774	R771W	771	Missense	distal	-3	no	10.248	9.486	EPSD;PhosphoSitePlus	ICGC	3.516	Down-regulation
AGC_PDK1_PDPK1_ST	Q16512	PKN1	O15530	PDPK1	T774	P779Q	779	Missense	distal	5	no	10.248	9.412	EPSD;PhosphoSitePlus	ICGC;COSMIC	3.516	Down-regulation
AGC_PDK1_PDPK1_ST	Q16512	PKN1	O15530	PDPK1	S791	T790M	790	Missense	proximal	-1	no	4.656	4.698	EPSD	ICGC;COSMIC;CCLE	3.516	Up-regulation
AGC_PDK1_PDPK1_ST	Q16512	PKN1	O15530	PDPK1	S791	V786L	786	Missense	distal	-5	no	4.656	4.807	EPSD	ICGC;COSMIC	3.516	Up-regulation
AGC_PDK1_PDPK1_ST	Q16512	PKN1	O15530	PDPK1	S791	P784L	784	Missense	distal	-7	no	4.656	3.704	EPSD	ICGC	3.516	Down-regulation
AGC_PDK1_PDPK1_ST	Q16512	PKN1	O15530	PDPK1	S916	R919H	919	Missense	distal	3	no	5.868	5.972	EPSD	ICGC;COSMIC	3.516	Up-regulation
AGC_PDK1_PDPK1_ST	Q99814	EPAS1	O15530	PDPK1	S210	N209D	209	Missense	proximal	-1	no	4.585	4.388	EPSD	ICGC;COSMIC	3.516	Down-regulation
AGC_PDK1_PDPK1_ST	Q99814	EPAS1	O15530	PDPK1	S210	P217S	217	Missense	distal	7	no	4.585	4.425	EPSD	ICGC;COSMIC	3.516	Down-regulation
AGC_PDK1_PDPK1_ST	Q99814	EPAS1	O15530	PDPK1	S210	C212F	212	Missense	proximal	2	no	4.585	4.519	EPSD	ICGC	3.516	Down-regulation
AGC_PDK1_PDPK1_ST	Q99814	EPAS1	O15530	PDPK1	T324	T324M	324	Missense	central	0	yes	5.953	0.000	PhosphoSitePlus	ICGC;COSMIC	3.516	Loss
AGC_PDK1_PDPK1_ST	Q99814	EPAS1	O15530	PDPK1	T324	V317M	317	Missense	distal	-7	no	5.953	6.371	PhosphoSitePlus	ICGC;COSMIC	3.516	Up-regulation
AGC_PDK1_PDPK1_ST	Q99814	EPAS1	O15530	PDPK1	S677	R682G	682	Missense	distal	5	no	4.508	4.821	EPSD	ICGC;COSMIC	3.516	Up-regulation
AGC_PDK1_PDPK1_ST	Q99814	EPAS1	O15530	PDPK1	T678	R682G	682	Missense	distal	4	no	4.790	4.179	EPSD	ICGC;COSMIC	3.516	Down-regulation
AGC_PDK1_PDPK1_ST	Q99814	EPAS1	O15530	PDPK1	S696	R690L	690	Missense	distal	-6	no	3.601	3.683	EPSD	ICGC;COSMIC	3.516	Up-regulation
AGC_PDK1_PDPK1_ST	Q99814	EPAS1	O15530	PDPK1	S696	A689S	689	Missense	distal	-7	no	3.601	3.979	EPSD	ICGC	3.516	Up-regulation
AGC_PDK1_PDPK1_ST	Q99814	EPAS1	O15530	PDPK1	S696	G691V	691	Missense	distal	-5	no	3.601	3.745	EPSD	ICGC	3.516	Up-regulation
AGC_PDK1_PDPK1_ST	P31751	AKT2	O15530	PDPK1	T309	T309N	309	Missense	central	0	yes	10.762	0.000	PhosphoSitePlus	ICGC	3.516	Loss
AGC_PDK1_PDPK1_ST	P31751	AKT2	O15530	PDPK1	T451	T449N	449	Missense	proximal	-2	no	5.456	5.378	EPSD	ICGC	3.516	Down-regulation
AGC_PDK1_PDPK1_ST	P05106	ITGB3	O15530	PDPK1	S110	V109G	109	Missense	proximal	-1	no	6.532	6.621	EPSD	ICGC;COSMIC	3.516	Up-regulation
AGC_PDK1_PDPK1_ST	P05106	ITGB3	O15530	PDPK1	S110	P111L	111	Missense	proximal	1	no	6.532	4.113	EPSD	ICGC;COSMIC	3.516	Down-regulation
AGC_PDK1_PDPK1_ST	P05106	ITGB3	O15530	PDPK1	S619	D622N	622	Missense	distal	3	no	4.333	4.376	EPSD	ICGC;COSMIC	3.516	Up-regulation
AGC_PDK1_PDPK1_ST	P05106	ITGB3	O15530	PDPK1	S619	P617L	617	Missense	proximal	-2	no	4.333	4.165	EPSD	ICGC;COSMIC	3.516	Down-regulation
AGC_PDK1_PDPK1_ST	P05106	ITGB3	O15530	PDPK1	S619	G621W	621	Missense	proximal	2	no	4.333	4.288	EPSD	ICGC;COSMIC	3.516	Down-regulation
AGC_PDK1_PDPK1_ST	P05106	ITGB3	O15530	PDPK1	T779	R786L	786	Missense	distal	7	no	4.971	4.694	PhosphoSitePlus	ICGC	3.516	Down-regulation
AGC_PDK1_PDPK1_ST	P05106	ITGB3	O15530	PDPK1	T784	R786L	786	Missense	proximal	2	no	4.331	4.261	EPSD	ICGC	3.516	Down-regulation
AGC_PDK1_PDPK1_ST	P23443	RPS6KB1	O15530	PDPK1	T444	P445T	445	Missense	proximal	1	no	6.492	3.526	EPSD	ICGC;COSMIC	3.516	Down-regulation
AGC_PDK1_PDPK1_ST	P23443	RPS6KB1	O15530	PDPK1	T444	S441N	441	Missense	distal	-3	no	6.492	5.911	EPSD	ICGC;COSMIC	3.516	Down-regulation
AGC_PDK1_PDPK1_ST	P17612	PRKACA	O15530	PDPK1	S54	G56W	56	Missense	proximal	2	no	6.069	6.024	EPSD	ICGC;COSMIC	3.516	Down-regulation
AGC_PDK1_PDPK1_ST	P17612	PRKACA	O15530	PDPK1	S54	S54Y	54	Missense	central	0	yes	6.069	0.000	EPSD	ICGC	3.516	Loss
AGC_PDK1_PDPK1_ST	P17612	PRKACA	O15530	PDPK1	S54	S54F	54	Missense	central	0	yes	6.069	0.000	EPSD	ICGC;COSMIC	3.516	Loss
AGC_PDK1_PDPK1_ST	P17612	PRKACA	O15530	PDPK1	T198	G194D	194	Missense	distal	-4	no	5.939	5.993	PhosphoSitePlus	ICGC;COSMIC	3.516	Up-regulation
AGC_PDK1_PDPK1_ST	P17612	PRKACA	O15530	PDPK1	T198	P203H	203	Missense	distal	5	no	5.939	5.390	PhosphoSitePlus	ICGC;COSMIC	3.516	Down-regulation
AGC_PDK1_PDPK1_ST	P31749	AKT1	O15530	PDPK1	T72	T65K	65	Missense	distal	-7	no	5.536	4.927	EPSD	ICGC	3.516	Down-regulation
AGC_PDK1_PDPK1_ST	P31749	AKT1	O15530	PDPK1	T92	H89R	89	Missense	distal	-3	no	3.431	3.912	EPSD	ICGC	3.516	Gain
AGC_PDK1_PDPK1_ST	P31749	AKT1	O15530	PDPK1	T92	E85K	85	Missense	distal	-7	no	3.431	3.519	EPSD	ICGC;COSMIC	3.516	Gain
AGC_PDK1_PDPK1_ST	P31749	AKT1	O15530	PDPK1	S137	R144H	144	Missense	distal	7	no	3.627	3.692	EPSD	ICGC	3.516	Up-regulation
AGC_PDK1_PDPK1_ST	P31749	AKT1	O15530	PDPK1	T308	T305N	305	Missense	distal	-3	no	10.175	9.634	EPSD;PhosphoSitePlus	ICGC	3.516	Down-regulation
AGC_PDK1_PDPK1_ST	P31749	AKT1	O15530	PDPK1	T450	Q454K	454	Missense	distal	4	no	5.080	4.998	EPSD	ICGC	3.516	Down-regulation
AGC_PDK1_PDPK1_ST	P31749	AKT1	O15530	PDPK1	T450	S457R	457	Missense	distal	7	no	5.080	4.954	EPSD	ICGC	3.516	Down-regulation
AGC_PDK1_PDPK1_ST	P31749	AKT1	O15530	PDPK1	S473	Q471K	471	Missense	proximal	-2	no	5.258	5.229	PhosphoSitePlus;EPSD	ICGC	3.516	Down-regulation
AGC_PDK1_PDPK1_ST	P31749	AKT1	O15530	PDPK1	S473	S477R	477	Missense	distal	4	no	5.258	4.931	PhosphoSitePlus;EPSD	ICGC	3.516	Down-regulation
AGC_PDK1_PDPK1_ST	O60331	PIP5K1C	O15530	PDPK1	T69	A65E	65	Missense	distal	-4	no	4.887	4.913	EPSD	ICGC;COSMIC	3.516	Up-regulation
AGC_PDK1_PDPK1_ST	O60331	PIP5K1C	O15530	PDPK1	T70	A65E	65	Missense	distal	-5	no	3.767	3.791	EPSD	ICGC;COSMIC	3.516	Up-regulation
AGC_PDK1_PDPK1_ST	O60331	PIP5K1C	O15530	PDPK1	S95	P98T	98	Missense	distal	3	no	3.944	3.811	EPSD	ICGC	3.516	Down-regulation
AGC_PDK1_PDPK1_ST	O60331	PIP5K1C	O15530	PDPK1	S424	R427H	427	Missense	distal	3	no	3.581	3.685	EPSD	ICGC	3.516	Up-regulation
AGC_PDK1_PDPK1_ST	O60331	PIP5K1C	O15530	PDPK1	S424	H426N	426	Missense	proximal	2	no	3.581	3.595	EPSD	ICGC	3.516	Up-regulation
AGC_PDK1_PDPK1_ST	O60331	PIP5K1C	O15530	PDPK1	S424	G420R	420	Missense	distal	-4	no	3.581	3.611	EPSD	ICGC;COSMIC	3.516	Up-regulation
AGC_PDK1_PDPK1_ST	O60331	PIP5K1C	O15530	PDPK1	T442	S449Y	449	Missense	distal	7	no	3.610	3.592	EPSD	ICGC	3.516	Down-regulation
AGC_PDK1_PDPK1_ST	O60331	PIP5K1C	O15530	PDPK1	T442	T442K	442	Missense	central	0	yes	3.610	0.000	EPSD	ICGC;COSMIC	3.516	Loss
AGC_PDK1_PDPK1_ST	O60331	PIP5K1C	O15530	PDPK1	S448	S449Y	449	Missense	proximal	1	no	4.948	6.906	PhosphoSitePlus	ICGC	3.516	Up-regulation
AGC_PDK1_PDPK1_ST	O60331	PIP5K1C	O15530	PDPK1	S448	T442K	442	Missense	distal	-6	no	4.948	4.978	PhosphoSitePlus	ICGC;COSMIC	3.516	Up-regulation
AGC_PDK1_PDPK1_ST	O60331	PIP5K1C	O15530	PDPK1	S448	S455P	455	Missense	distal	7	no	4.948	5.109	PhosphoSitePlus	ICGC;COSMIC	3.516	Up-regulation
AGC_PDK1_PDPK1_ST	O60331	PIP5K1C	O15530	PDPK1	T526	T526A	526	Missense	central	0	yes	4.696	0.000	EPSD	ICGC;COSMIC	3.516	Loss
AGC_PDK1_PDPK1_ST	O60331	PIP5K1C	O15530	PDPK1	S539	P536H	536	Missense	distal	-3	no	6.158	5.876	EPSD	ICGC	3.516	Down-regulation
AGC_PDK1_PDPK1_ST	O60331	PIP5K1C	O15530	PDPK1	S539	S544L	544	Missense	distal	5	no	6.158	5.052	EPSD	ICGC;COSMIC	3.516	Down-regulation
AGC_PDK1_PDPK1_ST	O60331	PIP5K1C	O15530	PDPK1	T543	P536H	536	Missense	distal	-7	no	3.666	3.297	EPSD	ICGC	3.516	Loss
AGC_PDK1_PDPK1_ST	O60331	PIP5K1C	O15530	PDPK1	T543	S544L	544	Missense	proximal	1	no	3.666	4.042	EPSD	ICGC;COSMIC	3.516	Up-regulation
AGC_PDK1_PDPK1_ST	O60331	PIP5K1C	O15530	PDPK1	S650	W647L	647	Missense	distal	-3	no	4.892	4.997	EPSD	ICGC;COSMIC	3.516	Up-regulation
AGC_PDK1_PDPK1_ST	O60331	PIP5K1C	O15530	PDPK1	S650	R645M	645	Missense	distal	-5	no	4.892	4.800	EPSD	ICGC;COSMIC	3.516	Down-regulation
AGC_PDK1_PDPK1_ST	O60331	PIP5K1C	O15530	PDPK1	S650	R645G	645	Missense	distal	-5	no	4.892	4.809	EPSD	ICGC;COSMIC;CCLE	3.516	Down-regulation
AGC_PDK1_PDPK1_ST	Q02750	MAP2K1	O15530	PDPK1	S222	G225C	225	Missense	distal	3	no	8.613	8.208	PhosphoSitePlus	ICGC	3.516	Down-regulation
AGC_PDK1_PDPK1_ST	Q02750	MAP2K1	O15530	PDPK1	S222	L215I	215	Missense	distal	-7	no	8.613	8.186	PhosphoSitePlus	ICGC;COSMIC	3.516	Down-regulation
AGC_PDK1_PDPK1_ST	Q02750	MAP2K1	O15530	PDPK1	S231	P232R	232	Missense	proximal	1	no	4.679	0.299	EPSD	ICGC	3.516	Loss
AGC_PDK1_PDPK1_ST	Q02750	MAP2K1	O15530	PDPK1	S231	R234I	234	Missense	distal	3	no	4.679	4.479	EPSD	ICGC	3.516	Down-regulation
AGC_PDK1_PDPK1_ST	Q02750	MAP2K1	O15530	PDPK1	S231	G225C	225	Missense	distal	-6	no	4.679	4.773	EPSD	ICGC	3.516	Up-regulation
AGC_PDK1_PDPK1_ST	Q02750	MAP2K1	O15530	PDPK1	T292	P288H	288	Missense	distal	-4	no	5.026	5.076	EPSD	ICGC;COSMIC	3.516	Up-regulation
AGC_PDK1_PDPK1_ST	Q02750	MAP2K1	O15530	PDPK1	T292	G294W	294	Missense	proximal	2	no	5.026	4.981	EPSD	ICGC;COSMIC	3.516	Down-regulation
AGC_PDK1_PDPK1_ST	Q02750	MAP2K1	O15530	PDPK1	T292	P296H	296	Missense	distal	4	no	5.026	4.533	EPSD	ICGC;COSMIC	3.516	Down-regulation
AGC_PDK1_PDPK1_ST	Q02750	MAP2K1	O15530	PDPK1	S299	G294W	294	Missense	distal	-5	no	3.809	4.033	EPSD	ICGC;COSMIC	3.516	Up-regulation
AGC_PDK1_PDPK1_ST	Q02750	MAP2K1	O15530	PDPK1	S299	P296H	296	Missense	distal	-3	no	3.809	3.527	EPSD	ICGC;COSMIC	3.516	Down-regulation
AGC_PDK1_PDPK1_ST	Q02750	MAP2K1	O15530	PDPK1	T386	S385G	385	Missense	proximal	-1	no	3.786	3.751	EPSD	ICGC	3.516	Down-regulation
AGC_PDK1_PDPK1_ST	Q96BR1	SGK3	O15530	PDPK1	S121	F116L	116	Missense	distal	-5	no	4.864	4.780	EPSD	ICGC	3.516	Down-regulation
AGC_PDK1_PDPK1_ST	Q96BR1	SGK3	O15530	PDPK1	S121	S121G	121	Missense	central	0	yes	4.864	0.000	EPSD	ICGC;COSMIC	3.516	Loss
AGC_PDK1_PDPK1_ST	Q96BR1	SGK3	O15530	PDPK1	T320	A313S	313	Missense	distal	-7	no	11.046	11.425	PhosphoSitePlus	ICGC	3.516	Up-regulation
AGC_PDK1_PDPK1_ST	Q96BR1	SGK3	O15530	PDPK1	T320	I314V	314	Missense	distal	-6	no	11.046	10.975	PhosphoSitePlus	ICGC;COSMIC	3.516	Down-regulation
AGC_PDK1_PDPK1_ST	Q96BR1	SGK3	O15530	PDPK1	T320	T318N	318	Missense	proximal	-2	no	11.046	10.969	PhosphoSitePlus	ICGC;COSMIC	3.516	Down-regulation
AGC_PDK1_PDPK1_ST	Q96BR1	SGK3	O15530	PDPK1	T320	G323V	323	Missense	distal	3	no	11.046	10.777	PhosphoSitePlus	ICGC;COSMIC	3.516	Down-regulation
AGC_PDK1_PDPK1_ST	Q9Y243	AKT3	O15530	PDPK1	T305	A300V	300	Missense	distal	-5	no	10.850	10.929	PhosphoSitePlus	ICGC;COSMIC	3.516	Up-regulation
AGC_PDK1_PDPK1_ST	Q9Y243	AKT3	O15530	PDPK1	T305	T309I	309	Missense	distal	4	no	10.850	9.495	PhosphoSitePlus	ICGC;COSMIC	3.516	Down-regulation
AGC_PDK1_PDPK1_ST	Q9Y243	AKT3	O15530	PDPK1	T447	T445R	445	Missense	proximal	-2	no	4.706	4.644	EPSD	ICGC;COSMIC	3.516	Down-regulation
AGC_PDK1_PDPK1_ST	Q9Y243	AKT3	O15530	PDPK1	S472	S472F	472	Missense	central	0	yes	5.564	0.000	EPSD	ICGC;COSMIC	3.516	Loss
AGC_PDK1_PDPK1_ST	O00141	SGK1	O15530	PDPK1	S74	P79A	79	Missense	distal	5	no	5.262	4.950	EPSD	ICGC;COSMIC	3.516	Down-regulation
AGC_PDK1_PDPK1_ST	O00141	SGK1	O15530	PDPK1	S74	L68V	68	Missense	distal	-6	no	5.262	5.222	EPSD	ICGC;COSMIC;CCLE	3.516	Down-regulation
AGC_PDK1_PDPK1_ST	O00141	SGK1	O15530	PDPK1	S74	P75T	75	Missense	proximal	1	no	5.262	2.295	EPSD	ICGC;COSMIC	3.516	Loss
AGC_PDK1_PDPK1_ST	O00141	SGK1	O15530	PDPK1	S74	A71P	71	Missense	distal	-3	no	5.262	5.560	EPSD	ICGC	3.516	Up-regulation
AGC_PDK1_PDPK1_ST	O00141	SGK1	O15530	PDPK1	S74	A71V	71	Missense	distal	-3	no	5.262	5.489	EPSD	ICGC;COSMIC	3.516	Up-regulation
AGC_PDK1_PDPK1_ST	O00141	SGK1	O15530	PDPK1	S74	A71D	71	Missense	distal	-3	no	5.262	4.919	EPSD	ICGC	3.516	Down-regulation
AGC_PDK1_PDPK1_ST	O00141	SGK1	O15530	PDPK1	S74	P73T	73	Missense	proximal	-1	no	5.262	5.290	EPSD	ICGC	3.516	Up-regulation
AGC_PDK1_PDPK1_ST	O00141	SGK1	O15530	PDPK1	S74	P76Q	76	Missense	proximal	2	no	5.262	5.236	EPSD	ICGC	3.516	Down-regulation
AGC_PDK1_PDPK1_ST	O00141	SGK1	O15530	PDPK1	S74	M69V	69	Missense	distal	-5	no	5.262	5.415	EPSD	ICGC;COSMIC	3.516	Up-regulation
AGC_PDK1_PDPK1_ST	O00141	SGK1	O15530	PDPK1	S74	P73S	73	Missense	proximal	-1	no	5.262	5.282	EPSD	ICGC;COSMIC	3.516	Up-regulation
AGC_PDK1_PDPK1_ST	O00141	SGK1	O15530	PDPK1	S74	P77S	77	Missense	distal	3	no	5.262	5.292	EPSD	ICGC;COSMIC	3.516	Up-regulation
AGC_PDK1_PDPK1_ST	O00141	SGK1	O15530	PDPK1	S74	P79L	79	Missense	distal	5	no	5.262	4.267	EPSD	ICGC;CCLE	3.516	Down-regulation
AGC_PDK1_PDPK1_ST	O00141	SGK1	O15530	PDPK1	S74	E67D	67	Missense	distal	-7	no	5.262	5.351	EPSD	ICGC	3.516	Up-regulation
AGC_PDK1_PDPK1_ST	O00141	SGK1	O15530	PDPK1	S74	S74Y	74	Missense	central	0	yes	5.262	0.000	EPSD	ICGC	3.516	Loss
AGC_PDK1_PDPK1_ST	O00141	SGK1	O15530	PDPK1	S74	M69L	69	Missense	distal	-5	no	5.262	5.566	EPSD	ICGC;COSMIC	3.516	Up-regulation
AGC_PDK1_PDPK1_ST	O00141	SGK1	O15530	PDPK1	S78	P79A	79	Missense	proximal	1	no	4.714	0.170	EPSD	ICGC;COSMIC	3.516	Loss
AGC_PDK1_PDPK1_ST	O00141	SGK1	O15530	PDPK1	S78	P75T	75	Missense	distal	-3	no	4.714	5.001	EPSD	ICGC;COSMIC	3.516	Up-regulation
AGC_PDK1_PDPK1_ST	O00141	SGK1	O15530	PDPK1	S78	A71P	71	Missense	distal	-7	no	4.714	5.118	EPSD	ICGC	3.516	Up-regulation
AGC_PDK1_PDPK1_ST	O00141	SGK1	O15530	PDPK1	S78	A71V	71	Missense	distal	-7	no	4.714	4.702	EPSD	ICGC;COSMIC	3.516	Down-regulation
AGC_PDK1_PDPK1_ST	O00141	SGK1	O15530	PDPK1	S78	A71D	71	Missense	distal	-7	no	4.714	4.508	EPSD	ICGC	3.516	Down-regulation
AGC_PDK1_PDPK1_ST	O00141	SGK1	O15530	PDPK1	S78	P73T	73	Missense	distal	-5	no	4.714	4.758	EPSD	ICGC	3.516	Up-regulation
AGC_PDK1_PDPK1_ST	O00141	SGK1	O15530	PDPK1	S78	P76Q	76	Missense	proximal	-2	no	4.714	4.611	EPSD	ICGC	3.516	Down-regulation
AGC_PDK1_PDPK1_ST	O00141	SGK1	O15530	PDPK1	S78	P73S	73	Missense	distal	-5	no	4.714	4.686	EPSD	ICGC;COSMIC	3.516	Down-regulation
AGC_PDK1_PDPK1_ST	O00141	SGK1	O15530	PDPK1	S78	P77S	77	Missense	proximal	-1	no	4.714	4.734	EPSD	ICGC;COSMIC	3.516	Up-regulation
AGC_PDK1_PDPK1_ST	O00141	SGK1	O15530	PDPK1	S78	P79L	79	Missense	proximal	1	no	4.714	2.295	EPSD	ICGC;CCLE	3.516	Loss
AGC_PDK1_PDPK1_ST	O00141	SGK1	O15530	PDPK1	S78	S74Y	74	Missense	distal	-4	no	4.714	4.779	EPSD	ICGC	3.516	Up-regulation
AGC_PDK1_PDPK1_ST	O00141	SGK1	O15530	PDPK1	T256	H250N	250	Missense	distal	-6	no	9.909	9.885	PhosphoSitePlus	ICGC	3.516	Down-regulation
AGC_PDK1_PDPK1_ST	O00141	SGK1	O15530	PDPK1	T256	T260S	260	Missense	distal	4	no	9.909	9.845	PhosphoSitePlus	ICGC	3.516	Down-regulation
AGC_PDK1_PDPK1_ST	O00141	SGK1	O15530	PDPK1	T256	T254A	254	Missense	proximal	-2	no	9.909	9.830	PhosphoSitePlus	ICGC	3.516	Down-regulation
AGC_PDK1_PDPK1_ST	O00141	SGK1	O15530	PDPK1	S401	D403E	403	Missense	proximal	2	no	3.654	3.669	EPSD	ICGC	3.516	Up-regulation
AGC_PDK1_PDPK1_ST	O00141	SGK1	O15530	PDPK1	S401	G399D	399	Missense	proximal	-2	no	3.654	3.617	EPSD	ICGC;COSMIC	3.516	Down-regulation
AGC_PDK1_PDPK1_ST	O00141	SGK1	O15530	PDPK1	S401	K400E	400	Missense	proximal	-1	no	3.654	3.534	EPSD	ICGC;COSMIC	3.516	Down-regulation
AGC_PDK1_PDPK1_ST	O00141	SGK1	O15530	PDPK1	S422	G420C	420	Missense	proximal	-2	no	4.947	4.848	EPSD	ICGC;COSMIC	3.516	Down-regulation
AGC_PDK1_PDPK1_ST	O00141	SGK1	O15530	PDPK1	S422	F418L	418	Missense	distal	-4	no	4.947	4.853	EPSD	ICGC	3.516	Down-regulation
AGC_PDK1_PDPK1_ST	O00141	SGK1	O15530	PDPK1	S422	E416K	416	Missense	distal	-6	no	4.947	4.929	EPSD	ICGC;COSMIC	3.516	Down-regulation
AGC_PDK1_PDPK1_ST	O00141	SGK1	O15530	PDPK1	S422	A424V	424	Missense	proximal	2	no	4.947	4.977	EPSD	ICGC;COSMIC	3.516	Up-regulation
AGC_PDK1_PDPK1_ST	O00141	SGK1	O15530	PDPK1	S422	F418C	418	Missense	distal	-4	no	4.947	4.859	EPSD	ICGC;COSMIC	3.516	Down-regulation
AGC_PDK1_PDPK1_ST	P36507	MAP2K2	O15530	PDPK1	S226	R231C	231	Missense	distal	5	no	8.691	7.807	PhosphoSitePlus	ICGC;COSMIC	3.516	Down-regulation
AGC_PDK1_PDPK1_ST	P36507	MAP2K2	O15530	PDPK1	S295	P298L	298	Missense	distal	3	no	4.451	4.069	EPSD	ICGC;COSMIC;GDSC	3.516	Down-regulation
AGC_PDK1_PDPK1_ST	P36507	MAP2K2	O15530	PDPK1	S295	P296T	296	Missense	proximal	1	no	4.451	1.484	EPSD	ICGC	3.516	Loss
AGC_PDK1_PDPK1_ST	P36507	MAP2K2	O15530	PDPK1	S295	P291T	291	Missense	distal	-4	no	4.451	4.462	EPSD	ICGC	3.516	Up-regulation
AGC_PDK1_PDPK1_ST	P36507	MAP2K2	O15530	PDPK1	S295	P300L	300	Missense	distal	5	no	4.451	3.457	EPSD	ICGC;COSMIC	3.516	Loss
AGC_PDK1_PDPK1_ST	P36507	MAP2K2	O15530	PDPK1	S295	S293G	293	Missense	proximal	-2	no	4.451	4.361	EPSD	ICGC;COSMIC	3.516	Down-regulation
AGC_PDK1_PDPK1_ST	P36507	MAP2K2	O15530	PDPK1	T394	R397C	397	Missense	distal	3	no	4.121	4.018	EPSD	ICGC;COSMIC	3.516	Down-regulation
AGC_PDK1_PDPK1_ST	Q13153	PAK1	O15530	PDPK1	T167	K162R	162	Missense	distal	-5	no	5.260	5.201	EPSD	ICGC;COSMIC	3.516	Down-regulation
AGC_PDK1_PDPK1_ST	Q13153	PAK1	O15530	PDPK1	S220	T219K	219	Missense	proximal	-1	no	5.995	5.905	EPSD	ICGC;CCLE	3.516	Down-regulation
AGC_PDK1_PDPK1_ST	Q13153	PAK1	O15530	PDPK1	S223	T230A	230	Missense	distal	7	no	3.592	3.366	EPSD	ICGC;COSMIC	3.516	Loss
AGC_PDK1_PDPK1_ST	Q13153	PAK1	O15530	PDPK1	S223	T219K	219	Missense	distal	-4	no	3.592	3.663	EPSD	ICGC;CCLE	3.516	Up-regulation
AGC_PDK1_PDPK1_ST	Q13153	PAK1	O15530	PDPK1	T415	T415N	415	Missense	central	0	yes	3.666	0.000	EPSD	ICGC;COSMIC	3.516	Loss
AGC_PDK1_PDPK1_ST	Q13153	PAK1	O15530	PDPK1	T415	P416L	416	Missense	proximal	1	no	3.666	1.247	EPSD	ICGC	3.516	Loss
AGC_PDK1_PDPK1_ST	Q13153	PAK1	O15530	PDPK1	S422	T415N	415	Missense	distal	-7	no	3.640	3.409	EPSD	ICGC;COSMIC	3.516	Loss
AGC_PDK1_PDPK1_ST	Q13153	PAK1	O15530	PDPK1	S422	P416L	416	Missense	distal	-6	no	3.640	3.729	EPSD	ICGC	3.516	Up-regulation
AGC_PDK1_PDPK1_ST	Q13153	PAK1	O15530	PDPK1	T423	P416L	416	Missense	distal	-7	no	6.335	5.383	PhosphoSitePlus	ICGC	3.516	Down-regulation
AGC_PDK1_PDPK1_ST	Q13153	PAK1	O15530	PDPK1	T481	L475I	475	Missense	distal	-6	no	5.140	5.172	EPSD	ICGC	3.516	Up-regulation
AGC_PDK1_PDPK1_ST	Q13153	PAK1	O15530	PDPK1	T531	P532L	532	Missense	proximal	1	no	4.012	1.592	EPSD	ICGC;COSMIC	3.516	Loss
AGC_PDK1_PDPK1_ST	Q05655	PRKCD	O15530	PDPK1	S302	Q296H	296	Missense	distal	-6	no	4.135	4.133	EPSD	ICGC;COSMIC	3.516	Down-regulation
AGC_PDK1_PDPK1_ST	Q05655	PRKCD	O15530	PDPK1	T451	A450S	450	Missense	proximal	-1	no	4.677	4.823	EPSD	ICGC	3.516	Up-regulation
AGC_PDK1_PDPK1_ST	Q05655	PRKCD	O15530	PDPK1	T451	A455T	455	Missense	distal	4	no	4.677	5.166	EPSD	ICGC	3.516	Up-regulation
AGC_PDK1_PDPK1_ST	Q16513	PKN2	O15530	PDPK1	T124	R130L	130	Missense	distal	6	no	3.979	3.981	EPSD	ICGC	3.516	Up-regulation
AGC_PDK1_PDPK1_ST	Q16513	PKN2	O15530	PDPK1	T124	C131F	131	Missense	distal	7	no	3.979	4.029	EPSD	ICGC	3.516	Up-regulation
AGC_PDK1_PDPK1_ST	Q16513	PKN2	O15530	PDPK1	S360	G358D	358	Missense	proximal	-2	no	5.874	5.837	EPSD	ICGC	3.516	Down-regulation
AGC_PDK1_PDPK1_ST	Q16513	PKN2	O15530	PDPK1	S360	S353T	353	Missense	distal	-7	no	5.874	5.897	EPSD	ICGC	3.516	Up-regulation
AGC_PDK1_PDPK1_ST	Q16513	PKN2	O15530	PDPK1	T533	S535Y	535	Missense	proximal	2	no	5.008	4.923	EPSD	ICGC;COSMIC	3.516	Down-regulation
AGC_PDK1_PDPK1_ST	Q16513	PKN2	O15530	PDPK1	S535	S535Y	535	Missense	central	0	yes	3.966	0.000	EPSD	ICGC;COSMIC	3.516	Loss
AGC_PDK1_PDPK1_ST	Q02156	PRKCE	O15530	PDPK1	T175	H170R	170	Missense	distal	-5	no	4.405	4.412	EPSD	ICGC	3.516	Up-regulation
AGC_PDK1_PDPK1_ST	Q02156	PRKCE	O15530	PDPK1	T309	G307D	307	Missense	proximal	-2	no	4.524	4.487	EPSD	ICGC	3.516	Down-regulation
AGC_PDK1_PDPK1_ST	Q02156	PRKCE	O15530	PDPK1	T309	V302L	302	Missense	distal	-7	no	4.524	3.988	EPSD	ICGC	3.516	Down-regulation
AGC_PDK1_PDPK1_ST	Q02156	PRKCE	O15530	PDPK1	S388	Q385H	385	Missense	distal	-3	no	4.817	5.070	EPSD	ICGC;COSMIC	3.516	Up-regulation
AGC_PDK1_PDPK1_ST	Q02156	PRKCE	O15530	PDPK1	S418	A425V	425	Missense	distal	7	no	4.839	4.923	EPSD	ICGC;COSMIC	3.516	Up-regulation
AGC_PDK1_PDPK1_ST	Q02156	PRKCE	O15530	PDPK1	T566	V562A	562	Missense	distal	-4	no	10.563	10.559	PhosphoSitePlus	ICGC;COSMIC	3.516	Down-regulation
AGC_PDK1_PDPK1_ST	Q02156	PRKCE	O15530	PDPK1	T566	F567L	567	Missense	proximal	1	no	10.563	7.602	PhosphoSitePlus	ICGC	3.516	Down-regulation
AGC_PDK1_PDPK1_ST	Q02156	PRKCE	O15530	PDPK1	T566	G569E	569	Missense	distal	3	no	10.563	10.466	PhosphoSitePlus	ICGC;COSMIC	3.516	Down-regulation
STE_STE11_ASK_MAP3K5_ST	Q9UER7	DAXX	Q99683	MAP3K5	S165	P160T	160	Missense	distal	-5	no	24.658	24.531	EPSD	ICGC;COSMIC	22.468	Down-regulation
STE_STE11_ASK_MAP3K5_ST	Q9UER7	DAXX	Q99683	MAP3K5	S176	R182S	182	Missense	distal	6	no	39.634	37.789	PhosphoSitePlus;EPSD	ICGC;COSMIC	22.468	Down-regulation
STE_STE11_ASK_MAP3K5_ST	Q9UER7	DAXX	Q99683	MAP3K5	S176	G183V	183	Missense	distal	7	no	39.634	39.479	PhosphoSitePlus;EPSD	ICGC;COSMIC	22.468	Down-regulation
STE_STE11_ASK_MAP3K5_ST	Q9UER7	DAXX	Q99683	MAP3K5	S184	R182S	182	Missense	proximal	-2	no	37.891	38.589	EPSD;PhosphoSitePlus	ICGC;COSMIC	22.468	Up-regulation
STE_STE11_ASK_MAP3K5_ST	Q9UER7	DAXX	Q99683	MAP3K5	S184	G183V	183	Missense	proximal	-1	no	37.891	37.907	EPSD;PhosphoSitePlus	ICGC;COSMIC	22.468	Up-regulation
STE_STE11_ASK_MAP3K5_ST	Q9UER7	DAXX	Q99683	MAP3K5	S647	P643T	643	Missense	distal	-4	no	23.166	23.220	EPSD	ICGC;COSMIC	22.468	Up-regulation
STE_STE11_ASK_MAP3K5_ST	Q9UER7	DAXX	Q99683	MAP3K5	T684	T684M	684	Missense	central	0	yes	24.662	0.000	EPSD	ICGC;COSMIC	22.468	Loss
STE_STE11_ASK_MAP3K5_ST	Q9UER7	DAXX	Q99683	MAP3K5	T684	P678L	678	Missense	distal	-6	no	24.662	24.685	EPSD	ICGC	22.468	Up-regulation
STE_STE11_ASK_MAP3K5_ST	P46734	MAP2K3	Q99683	MAP3K5	T117	F121L	121	Missense	distal	4	no	29.389	29.871	EPSD	ICGC;COSMIC	22.468	Up-regulation
STE_STE11_ASK_MAP3K5_ST	P45983	MAPK8	Q99683	MAP3K5	S179	S179I	179	Missense	central	0	yes	29.048	0.000	EPSD	ICGC	22.468	Loss
STE_STE11_ASK_MAP3K5_ST	P45983	MAPK8	Q99683	MAP3K5	S179	T183M	183	Missense	distal	4	no	29.048	27.885	EPSD	ICGC;COSMIC	22.468	Down-regulation
STE_STE11_ASK_MAP3K5_ST	P45983	MAPK8	Q99683	MAP3K5	T183	R189P	189	Missense	distal	6	no	46.269	46.530	PhosphoSitePlus;EPSD	ICGC;COSMIC	22.468	Up-regulation
STE_STE11_ASK_MAP3K5_ST	P45983	MAPK8	Q99683	MAP3K5	T183	S179I	179	Missense	distal	-4	no	46.269	44.278	PhosphoSitePlus;EPSD	ICGC	22.468	Down-regulation
STE_STE11_ASK_MAP3K5_ST	P45983	MAPK8	Q99683	MAP3K5	T183	T183M	183	Missense	central	0	yes	46.269	0.000	PhosphoSitePlus;EPSD	ICGC;COSMIC	22.468	Loss
STE_STE11_ASK_MAP3K5_ST	Q8IUQ4	SIAH1	Q99683	MAP3K5	S19	C16Y	16	Missense	distal	-3	no	21.393	22.586	EPSD	ICGC	22.468	Gain
STE_STE11_ASK_MAP3K5_ST	Q8IUQ4	SIAH1	Q99683	MAP3K5	S19	P23T	23	Missense	distal	4	no	21.393	22.816	EPSD	ICGC	22.468	Gain
STE_STE11_ASK_MAP3K5_ST	P52564	MAP2K6	Q99683	MAP3K5	T211	P218Q	218	Missense	distal	7	no	29.569	29.239	EPSD	ICGC;COSMIC	22.468	Down-regulation
STE_STE11_ASK_MAP3K5_ST	Q16539	MAPK14	Q99683	MAP3K5	T123	D125Y	125	Missense	proximal	2	no	19.732	22.673	EPSD	ICGC	22.468	Gain
STE_STE11_ASK_MAP3K5_ST	Q15691	MAPRE1	Q99683	MAP3K5	S40	E36V	36	Missense	distal	-4	no	37.183	36.779	EPSD;PhosphoSitePlus	ICGC;COSMIC	22.468	Down-regulation
STE_STE11_ASK_MAP3K5_ST	Q15691	MAPRE1	Q99683	MAP3K5	S40	Q37H	37	Missense	distal	-3	no	37.183	37.771	EPSD;PhosphoSitePlus	ICGC	22.468	Up-regulation
STE_STE11_ASK_MAP3K5_ST	Q15691	MAPRE1	Q99683	MAP3K5	S40	L38F	38	Missense	proximal	-2	no	37.183	37.545	EPSD;PhosphoSitePlus	ICGC	22.468	Up-regulation
STE_STE11_ASK_MAP3K5_ST	Q15691	MAPRE1	Q99683	MAP3K5	T206	L203F	203	Missense	distal	-3	no	41.243	42.296	PhosphoSitePlus;EPSD	ICGC	22.468	Up-regulation
STE_STE11_ASK_MAP3K5_ST	P38936	CDKN1A	Q99683	MAP3K5	S160	K163N	163	Missense	distal	3	no	24.134	20.697	EPSD	ICGC	22.468	Loss
TK_VEGFR_KDR_Y	P35968	KDR	P35968	KDR	Y951	V952I	952	Missense	proximal	1	no	75.999	76.186	PhosphoSitePlus;EPSD	ICGC;COSMIC	61.410	Up-regulation
TK_VEGFR_KDR_Y	P35968	KDR	P35968	KDR	Y1054	A1050D	1050	Missense	distal	-4	no	66.935	66.859	EPSD;PhosphoSitePlus	ICGC	61.410	Down-regulation
TK_VEGFR_KDR_Y	P35968	KDR	P35968	KDR	Y1054	A1050V	1050	Missense	distal	-4	no	66.935	66.853	EPSD;PhosphoSitePlus	ICGC;COSMIC	61.410	Down-regulation
TK_VEGFR_KDR_Y	P35968	KDR	P35968	KDR	Y1054	D1052H	1052	Missense	proximal	-2	no	66.935	56.007	EPSD;PhosphoSitePlus	ICGC;COSMIC	61.410	Loss
TK_VEGFR_KDR_Y	P35968	KDR	P35968	KDR	Y1059	D1052H	1052	Missense	distal	-7	no	66.389	68.650	EPSD;PhosphoSitePlus	ICGC;COSMIC	61.410	Up-regulation
TK_VEGFR_KDR_Y	P35968	KDR	P35968	KDR	Y1059	D1064N	1064	Missense	distal	5	no	66.389	68.301	EPSD;PhosphoSitePlus	ICGC	61.410	Up-regulation
TK_VEGFR_KDR_Y	P35968	KDR	P35968	KDR	Y1175	Q1170K	1170	Missense	distal	-5	no	74.229	73.477	EPSD;PhosphoSitePlus	ICGC	61.410	Down-regulation
TK_VEGFR_KDR_Y	P35968	KDR	P35968	KDR	Y1214	A1218G	1218	Missense	distal	4	no	92.464	92.830	EPSD;PhosphoSitePlus	ICGC;COSMIC	61.410	Up-regulation
TK_VEGFR_KDR_Y	P35968	KDR	P35968	KDR	Y1214	S1221N	1221	Missense	distal	7	no	92.464	92.690	EPSD;PhosphoSitePlus	ICGC;COSMIC	61.410	Up-regulation
TK_VEGFR_KDR_Y	P07737	PFN1	P35968	KDR	Y129	E130G	130	Missense	proximal	1	no	78.064	78.232	PhosphoSitePlus	ICGC	61.410	Up-regulation
TK_VEGFR_KDR_Y	P07737	PFN1	P35968	KDR	Y129	M131I	131	Missense	proximal	2	no	78.064	78.132	PhosphoSitePlus	ICGC;COSMIC	61.410	Up-regulation
AGC_GRK_GRK_GRK5_ST	P07550	ADRB2	P34947	GRK5	S261	R259H	259	Missense	proximal	-2	no	2.394	2.393	EPSD	ICGC;COSMIC;GDSC;CCLE	1.854	Down-regulation
AGC_GRK_GRK_GRK5_ST	P07550	ADRB2	P34947	GRK5	S261	K267N	267	Missense	distal	6	no	2.394	2.371	EPSD	ICGC;COSMIC	1.854	Down-regulation
AGC_GRK_GRK_GRK5_ST	P07550	ADRB2	P34947	GRK5	S355	N352H	352	Missense	distal	-3	no	4.350	4.170	EPSD;PhosphoSitePlus	ICGC	1.854	Down-regulation
AGC_GRK_GRK_GRK5_ST	P07550	ADRB2	P34947	GRK5	S356	N352H	352	Missense	distal	-4	no	4.158	4.046	EPSD;PhosphoSitePlus	ICGC	1.854	Down-regulation
AGC_GRK_GRK_GRK5_ST	P07550	ADRB2	P34947	GRK5	T384	P382L	382	Missense	proximal	-2	no	3.672	3.674	EPSD;PhosphoSitePlus	ICGC;COSMIC	1.854	Up-regulation
AGC_GRK_GRK_GRK5_ST	P07550	ADRB2	P34947	GRK5	T384	T384M	384	Missense	central	0	yes	3.672	0.000	EPSD;PhosphoSitePlus	ICGC	1.854	Loss
AGC_GRK_GRK_GRK5_ST	P26038	MSN	P34947	GRK5	S504	D497Y	497	Missense	distal	-7	no	2.004	1.976	EPSD	ICGC	1.854	Down-regulation
AGC_GRK_GRK_GRK5_ST	P26038	MSN	P34947	GRK5	T510	R517C	517	Missense	distal	7	no	2.188	1.917	EPSD	ICGC	1.854	Down-regulation
AGC_GRK_GRK_GRK5_ST	P26038	MSN	P34947	GRK5	T510	R517L	517	Missense	distal	7	no	2.188	2.166	EPSD	ICGC	1.854	Down-regulation
AGC_GRK_GRK_GRK5_ST	P34947	GRK5	P34947	GRK5	S484	V489I	489	Missense	distal	5	no	4.708	4.450	EPSD;PhosphoSitePlus	ICGC;COSMIC	1.854	Down-regulation
AGC_GRK_GRK_GRK5_ST	P34947	GRK5	P34947	GRK5	S484	T485N	485	Missense	proximal	1	no	4.708	4.787	EPSD;PhosphoSitePlus	ICGC;COSMIC	1.854	Up-regulation
AGC_GRK_GRK_GRK5_ST	P34947	GRK5	P34947	GRK5	S484	V477L	477	Missense	distal	-7	no	4.708	4.644	EPSD;PhosphoSitePlus	ICGC	1.854	Down-regulation
AGC_GRK_GRK_GRK5_ST	P34947	GRK5	P34947	GRK5	S484	S484F	484	Missense	central	0	yes	4.708	0.000	EPSD;PhosphoSitePlus	ICGC	1.854	Loss
AGC_GRK_GRK_GRK5_ST	P34947	GRK5	P34947	GRK5	T485	V489I	489	Missense	distal	4	no	4.817	4.821	PhosphoSitePlus;EPSD	ICGC;COSMIC	1.854	Up-regulation
AGC_GRK_GRK_GRK5_ST	P34947	GRK5	P34947	GRK5	T485	T485N	485	Missense	central	0	yes	4.817	0.000	PhosphoSitePlus;EPSD	ICGC;COSMIC	1.854	Loss
AGC_GRK_GRK_GRK5_ST	P34947	GRK5	P34947	GRK5	T485	S484F	484	Missense	proximal	-1	no	4.817	4.861	PhosphoSitePlus;EPSD	ICGC	1.854	Up-regulation
AGC_GRK_GRK_GRK5_ST	P04637	TP53	P34947	GRK5	S9	E11K	11	Missense	proximal	2	no	2.827	2.549	EPSD	ICGC;COSMIC	1.854	Down-regulation
AGC_GRK_GRK_GRK5_ST	P04637	TP53	P34947	GRK5	S33	P34L	34	Missense	proximal	1	no	3.196	3.343	EPSD	ICGC;COSMIC	1.854	Up-regulation
AGC_GRK_GRK_GRK5_ST	P04637	TP53	P34947	GRK5	S33	S33F	33	Missense	central	0	yes	3.196	0.000	EPSD	ICGC;COSMIC	1.854	Loss
AGC_GRK_GRK_GRK5_ST	P04637	TP53	P34947	GRK5	S33	N30I	30	Missense	distal	-3	no	3.196	2.858	EPSD	ICGC	1.854	Down-regulation
AGC_GRK_GRK_GRK5_ST	P04637	TP53	P34947	GRK5	S37	P34L	34	Missense	distal	-3	no	2.381	2.331	EPSD	ICGC;COSMIC	1.854	Down-regulation
AGC_GRK_GRK_GRK5_ST	P04637	TP53	P34947	GRK5	S37	S33F	33	Missense	distal	-4	no	2.381	2.207	EPSD	ICGC;COSMIC	1.854	Down-regulation
AGC_GRK_GRK_GRK5_ST	P04637	TP53	P34947	GRK5	S37	N30I	30	Missense	distal	-7	no	2.381	2.173	EPSD	ICGC	1.854	Down-regulation
AGC_GRK_GRK_GRK5_ST	P04637	TP53	P34947	GRK5	T55	D48G	48	Missense	distal	-7	no	4.317	4.219	PhosphoSitePlus	ICGC;COSMIC	1.854	Down-regulation
AGC_GRK_GRK_GRK5_ST	P04637	TP53	P34947	GRK5	T55	Q52K	52	Missense	distal	-3	no	4.317	4.331	PhosphoSitePlus	ICGC	1.854	Up-regulation
AGC_GRK_GRK_GRK5_ST	P04637	TP53	P34947	GRK5	T55	E62K	62	Missense	distal	7	no	4.317	4.210	PhosphoSitePlus	ICGC;COSMIC	1.854	Down-regulation
AGC_GRK_GRK_GRK5_ST	P04637	TP53	P34947	GRK5	T150	P152R	152	Missense	proximal	2	no	1.750	1.918	EPSD	ICGC;COSMIC	1.854	Gain
AGC_GRK_GRK_GRK5_ST	P04637	TP53	P34947	GRK5	S313	T312I	312	Missense	proximal	-1	no	1.908	1.845	EPSD	ICGC;COSMIC	1.854	Loss
AGC_GRK_GRK_GRK5_ST	O60353	FZD6	P34947	GRK5	S517	R511H	511	Missense	distal	-6	no	2.447	2.477	EPSD	ICGC	1.854	Up-regulation
AGC_GRK_GRK_GRK5_ST	O60353	FZD6	P34947	GRK5	S517	I516L	516	Missense	proximal	-1	no	2.447	2.536	EPSD	ICGC;COSMIC	1.854	Up-regulation
AGC_GRK_GRK_GRK5_ST	P37840	SNCA	P34947	GRK5	S129	Q134K	134	Missense	distal	5	no	1.896	1.792	PhosphoSitePlus	ICGC;COSMIC	1.854	Loss
CMGC_CK2_CSNK2A2_ST	P18887	XRCC1	P19784	CSNK2A2	S421	S421R	421	Missense	central	0	yes	0.001	0.000	EPSD	ICGC	0.001	Loss
CMGC_CK2_CSNK2A2_ST	P35222	CTNNB1	P19784	CSNK2A2	T3	T3N	3	Missense	central	0	yes	0.001	0.000	EPSD	ICGC;COSMIC	0.001	Loss
CMGC_CK2_CSNK2A2_ST	Q9UQE7	SMC3	P19784	CSNK2A2	S13	D16Y	16	Missense	distal	3	no	0.001	0.000	EPSD	ICGC	0.001	Loss
CMGC_CK2_CSNK2A2_ST	Q9UQE7	SMC3	P19784	CSNK2A2	S674	E677G	677	Missense	distal	3	no	0.001	0.000	EPSD	ICGC;COSMIC	0.001	Loss
CMGC_CK2_CSNK2A2_ST	P67870	CSNK2B	P19784	CSNK2A2	S3	S3R	3	Missense	central	0	yes	0.001	0.000	PhosphoSitePlus;EPSD	ICGC;COSMIC	0.001	Loss
CMGC_CK2_CSNK2A2_ST	Q16543	CDC37	P19784	CSNK2A2	S5	S5G	5	Missense	central	0	yes	0.001	0.000	EPSD	ICGC	0.001	Loss
CMGC_CK2_CSNK2A2_ST	Q16543	CDC37	P19784	CSNK2A2	T136	T136M	136	Missense	central	0	yes	0.001	0.000	EPSD	ICGC;COSMIC	0.001	Loss
CMGC_CK2_CSNK2A2_ST	O15350	TP73	P19784	CSNK2A2	T27	D30Y	30	Missense	distal	3	no	0.001	0.000	PhosphoSitePlus	ICGC	0.001	Loss
TKL_STKR_STKR1_ACVRL1_ST	P17813	ENG	P37023	ACVRL1	T640	E636A	636	Missense	distal	-4	no	1.947	1.912	PhosphoSitePlus;EPSD	ICGC;COSMIC	0.461	Down-regulation
TKL_LRRK_LRRK2_ST	Q5S007	LRRK2	Q5S007	LRRK2	T424	N429S	429	Missense	distal	5	no	17.358	16.807	EPSD;PhosphoSitePlus	ICGC;COSMIC	15.080	Down-regulation
TKL_LRRK_LRRK2_ST	Q5S007	LRRK2	Q5S007	LRRK2	T424	A421T	421	Missense	distal	-3	no	17.358	17.221	EPSD;PhosphoSitePlus	ICGC;COSMIC	15.080	Down-regulation
TKL_LRRK_LRRK2_ST	Q5S007	LRRK2	Q5S007	LRRK2	T424	A419V	419	Missense	distal	-5	no	17.358	17.267	EPSD;PhosphoSitePlus	ICGC;COSMIC;GDSC	15.080	Down-regulation
TKL_LRRK_LRRK2_ST	Q5S007	LRRK2	Q5S007	LRRK2	T776	Q769H	769	Missense	distal	-7	no	16.256	16.078	EPSD;PhosphoSitePlus	ICGC	15.080	Down-regulation
TKL_LRRK_LRRK2_ST	Q5S007	LRRK2	Q5S007	LRRK2	T776	G782V	782	Missense	distal	6	no	16.256	16.158	EPSD;PhosphoSitePlus	ICGC;COSMIC	15.080	Down-regulation
TKL_LRRK_LRRK2_ST	Q5S007	LRRK2	Q5S007	LRRK2	T826	G819C	819	Missense	distal	-7	no	15.693	15.379	EPSD;PhosphoSitePlus	ICGC;COSMIC	15.080	Down-regulation
TKL_LRRK_LRRK2_ST	Q5S007	LRRK2	Q5S007	LRRK2	T826	L829I	829	Missense	distal	3	no	15.693	15.692	EPSD;PhosphoSitePlus	ICGC;COSMIC	15.080	Down-regulation
TKL_LRRK_LRRK2_ST	Q5S007	LRRK2	Q5S007	LRRK2	T833	I835V	835	Missense	proximal	2	no	16.763	16.498	EPSD;PhosphoSitePlus	ICGC;COSMIC	15.080	Down-regulation
TKL_LRRK_LRRK2_ST	Q5S007	LRRK2	Q5S007	LRRK2	T833	L829I	829	Missense	distal	-4	no	16.763	16.983	EPSD;PhosphoSitePlus	ICGC;COSMIC	15.080	Up-regulation
TKL_LRRK_LRRK2_ST	Q5S007	LRRK2	Q5S007	LRRK2	T838	I835V	835	Missense	distal	-3	no	17.022	16.972	EPSD;PhosphoSitePlus	ICGC;COSMIC	15.080	Down-regulation
TKL_LRRK_LRRK2_ST	Q5S007	LRRK2	Q5S007	LRRK2	S1124	P1125L	1125	Missense	proximal	1	no	16.883	16.978	EPSD;PhosphoSitePlus	ICGC	15.080	Up-regulation
TKL_LRRK_LRRK2_ST	Q5S007	LRRK2	Q5S007	LRRK2	S1219	R1223K	1223	Missense	distal	4	no	15.640	14.979	EPSD	ICGC;COSMIC	15.080	Loss
TKL_LRRK_LRRK2_ST	Q5S007	LRRK2	Q5S007	LRRK2	S1219	G1213V	1213	Missense	distal	-6	no	15.640	16.200	EPSD	ICGC	15.080	Up-regulation
TKL_LRRK_LRRK2_ST	Q5S007	LRRK2	Q5S007	LRRK2	S1219	L1220F	1220	Missense	proximal	1	no	15.640	15.467	EPSD	ICGC;COSMIC	15.080	Down-regulation
TKL_LRRK_LRRK2_ST	Q5S007	LRRK2	Q5S007	LRRK2	S1219	P1212Q	1212	Missense	distal	-7	no	15.640	15.424	EPSD	ICGC;COSMIC	15.080	Down-regulation
TKL_LRRK_LRRK2_ST	Q5S007	LRRK2	Q5S007	LRRK2	S1253	L1257P	1257	Missense	distal	4	no	15.314	14.040	EPSD;PhosphoSitePlus	ICGC	15.080	Loss
TKL_LRRK_LRRK2_ST	Q5S007	LRRK2	Q5S007	LRRK2	S1253	N1255Y	1255	Missense	proximal	2	no	15.314	14.954	EPSD;PhosphoSitePlus	ICGC;COSMIC	15.080	Loss
TKL_LRRK_LRRK2_ST	Q5S007	LRRK2	Q5S007	LRRK2	S1283	S1276R	1276	Missense	distal	-7	no	15.818	16.503	EPSD;PhosphoSitePlus	ICGC	15.080	Up-regulation
TKL_LRRK_LRRK2_ST	Q5S007	LRRK2	Q5S007	LRRK2	S1283	F1284I	1284	Missense	proximal	1	no	15.818	15.943	EPSD;PhosphoSitePlus	ICGC	15.080	Up-regulation
TKL_LRRK_LRRK2_ST	Q5S007	LRRK2	Q5S007	LRRK2	S1283	L1281P	1281	Missense	proximal	-2	no	15.818	15.863	EPSD;PhosphoSitePlus	ICGC	15.080	Up-regulation
TKL_LRRK_LRRK2_ST	Q5S007	LRRK2	Q5S007	LRRK2	S1283	P1285S	1285	Missense	proximal	2	no	15.818	16.060	EPSD;PhosphoSitePlus	ICGC;CCLE	15.080	Up-regulation
TKL_LRRK_LRRK2_ST	Q5S007	LRRK2	Q5S007	LRRK2	S1292	D1296H	1296	Missense	distal	4	no	17.748	18.436	EPSD;PhosphoSitePlus	ICGC;COSMIC	15.080	Up-regulation
TKL_LRRK_LRRK2_ST	Q5S007	LRRK2	Q5S007	LRRK2	S1292	P1285S	1285	Missense	distal	-7	no	17.748	17.374	EPSD;PhosphoSitePlus	ICGC;CCLE	15.080	Down-regulation
TKL_LRRK_LRRK2_ST	Q5S007	LRRK2	Q5S007	LRRK2	S1292	P1298H	1298	Missense	distal	6	no	17.748	17.573	EPSD;PhosphoSitePlus	ICGC;COSMIC	15.080	Down-regulation
TKL_LRRK_LRRK2_ST	Q5S007	LRRK2	Q5S007	LRRK2	T1343	M1338T	1338	Missense	distal	-5	no	16.822	16.703	EPSD;PhosphoSitePlus	ICGC;COSMIC	15.080	Down-regulation
TKL_LRRK_LRRK2_ST	Q5S007	LRRK2	Q5S007	LRRK2	T1343	G1344W	1344	Missense	proximal	1	no	16.822	16.315	EPSD;PhosphoSitePlus	ICGC	15.080	Down-regulation
TKL_LRRK_LRRK2_ST	Q5S007	LRRK2	Q5S007	LRRK2	T1343	V1340L	1340	Missense	distal	-3	no	16.822	16.880	EPSD;PhosphoSitePlus	ICGC	15.080	Up-regulation
TKL_LRRK_LRRK2_ST	Q5S007	LRRK2	Q5S007	LRRK2	S1345	M1338T	1338	Missense	distal	-7	no	17.472	17.703	EPSD;PhosphoSitePlus	ICGC;COSMIC	15.080	Up-regulation
TKL_LRRK_LRRK2_ST	Q5S007	LRRK2	Q5S007	LRRK2	S1345	G1344W	1344	Missense	proximal	-1	no	17.472	14.854	EPSD;PhosphoSitePlus	ICGC	15.080	Loss
TKL_LRRK_LRRK2_ST	Q5S007	LRRK2	Q5S007	LRRK2	S1345	V1340L	1340	Missense	distal	-5	no	17.472	17.560	EPSD;PhosphoSitePlus	ICGC	15.080	Up-regulation
TKL_LRRK_LRRK2_ST	Q5S007	LRRK2	Q5S007	LRRK2	T1348	G1344W	1344	Missense	distal	-4	no	17.633	15.951	EPSD;PhosphoSitePlus	ICGC	15.080	Down-regulation
TKL_LRRK_LRRK2_ST	Q5S007	LRRK2	Q5S007	LRRK2	T1368	D1361Y	1361	Missense	distal	-7	no	17.975	16.853	EPSD;PhosphoSitePlus	ICGC;COSMIC	15.080	Down-regulation
TKL_LRRK_LRRK2_ST	Q5S007	LRRK2	Q5S007	LRRK2	S1403	R1398H	1398	Missense	distal	-5	no	16.773	16.534	EPSD;PhosphoSitePlus	ICGC;COSMIC	15.080	Down-regulation
TKL_LRRK_LRRK2_ST	Q5S007	LRRK2	Q5S007	LRRK2	S1403	S1403C	1403	Missense	central	0	yes	16.773	0.000	EPSD;PhosphoSitePlus	ICGC	15.080	Loss
TKL_LRRK_LRRK2_ST	Q5S007	LRRK2	Q5S007	LRRK2	S1403	T1410M	1410	Missense	distal	7	no	16.773	16.728	EPSD;PhosphoSitePlus	ICGC	15.080	Down-regulation
TKL_LRRK_LRRK2_ST	Q5S007	LRRK2	Q5S007	LRRK2	S1403	T1404N	1404	Missense	proximal	1	no	16.773	16.840	EPSD;PhosphoSitePlus	ICGC;COSMIC	15.080	Up-regulation
TKL_LRRK_LRRK2_ST	Q5S007	LRRK2	Q5S007	LRRK2	S1403	T1410K	1410	Missense	distal	7	no	16.773	16.720	EPSD;PhosphoSitePlus	ICGC;COSMIC	15.080	Down-regulation
TKL_LRRK_LRRK2_ST	Q5S007	LRRK2	Q5S007	LRRK2	S1403	R1398C	1398	Missense	distal	-5	no	16.773	16.630	EPSD;PhosphoSitePlus	ICGC;COSMIC	15.080	Down-regulation
TKL_LRRK_LRRK2_ST	Q5S007	LRRK2	Q5S007	LRRK2	T1404	R1398H	1398	Missense	distal	-6	no	16.083	14.734	EPSD;PhosphoSitePlus	ICGC;COSMIC	15.080	Loss
TKL_LRRK_LRRK2_ST	Q5S007	LRRK2	Q5S007	LRRK2	T1404	S1403C	1403	Missense	proximal	-1	no	16.083	15.398	EPSD;PhosphoSitePlus	ICGC	15.080	Down-regulation
TKL_LRRK_LRRK2_ST	Q5S007	LRRK2	Q5S007	LRRK2	T1404	T1410M	1410	Missense	distal	6	no	16.083	16.394	EPSD;PhosphoSitePlus	ICGC	15.080	Up-regulation
TKL_LRRK_LRRK2_ST	Q5S007	LRRK2	Q5S007	LRRK2	T1404	T1404N	1404	Missense	central	0	yes	16.083	0.000	EPSD;PhosphoSitePlus	ICGC;COSMIC	15.080	Loss
TKL_LRRK_LRRK2_ST	Q5S007	LRRK2	Q5S007	LRRK2	T1404	T1410K	1410	Missense	distal	6	no	16.083	16.165	EPSD;PhosphoSitePlus	ICGC;COSMIC	15.080	Up-regulation
TKL_LRRK_LRRK2_ST	Q5S007	LRRK2	Q5S007	LRRK2	T1404	R1398C	1398	Missense	distal	-6	no	16.083	16.390	EPSD;PhosphoSitePlus	ICGC;COSMIC	15.080	Up-regulation
TKL_LRRK_LRRK2_ST	Q5S007	LRRK2	Q5S007	LRRK2	T1410	S1403C	1403	Missense	distal	-7	no	17.094	16.862	EPSD;PhosphoSitePlus	ICGC	15.080	Down-regulation
TKL_LRRK_LRRK2_ST	Q5S007	LRRK2	Q5S007	LRRK2	T1410	T1410M	1410	Missense	central	0	yes	17.094	0.000	EPSD;PhosphoSitePlus	ICGC	15.080	Loss
TKL_LRRK_LRRK2_ST	Q5S007	LRRK2	Q5S007	LRRK2	T1410	R1412L	1412	Missense	proximal	2	no	17.094	16.520	EPSD;PhosphoSitePlus	ICGC;COSMIC	15.080	Down-regulation
TKL_LRRK_LRRK2_ST	Q5S007	LRRK2	Q5S007	LRRK2	T1410	T1404N	1404	Missense	distal	-6	no	17.094	18.626	EPSD;PhosphoSitePlus	ICGC;COSMIC	15.080	Up-regulation
TKL_LRRK_LRRK2_ST	Q5S007	LRRK2	Q5S007	LRRK2	T1410	T1410K	1410	Missense	central	0	yes	17.094	0.000	EPSD;PhosphoSitePlus	ICGC;COSMIC	15.080	Loss
TKL_LRRK_LRRK2_ST	Q5S007	LRRK2	Q5S007	LRRK2	S1443	P1446L	1446	Missense	distal	3	no	16.548	16.684	EPSD;PhosphoSitePlus	ICGC;COSMIC;GDSC	15.080	Up-regulation
TKL_LRRK_LRRK2_ST	Q5S007	LRRK2	Q5S007	LRRK2	S1444	P1446L	1446	Missense	proximal	2	no	15.938	16.384	EPSD;PhosphoSitePlus	ICGC;COSMIC;GDSC	15.080	Up-regulation
TKL_LRRK_LRRK2_ST	Q5S007	LRRK2	Q5S007	LRRK2	S1445	P1446L	1446	Missense	proximal	1	no	15.500	15.596	EPSD;PhosphoSitePlus	ICGC;COSMIC;GDSC	15.080	Up-regulation
TKL_LRRK_LRRK2_ST	Q5S007	LRRK2	Q5S007	LRRK2	T1452	E1459K	1459	Missense	distal	7	no	16.299	16.278	EPSD;PhosphoSitePlus	ICGC	15.080	Down-regulation
TKL_LRRK_LRRK2_ST	Q5S007	LRRK2	Q5S007	LRRK2	T1452	D1458Y	1458	Missense	distal	6	no	16.299	16.453	EPSD;PhosphoSitePlus	ICGC	15.080	Up-regulation
TKL_LRRK_LRRK2_ST	Q5S007	LRRK2	Q5S007	LRRK2	T1452	V1456F	1456	Missense	distal	4	no	16.299	15.890	EPSD;PhosphoSitePlus	ICGC	15.080	Down-regulation
TKL_LRRK_LRRK2_ST	Q5S007	LRRK2	Q5S007	LRRK2	T1452	P1446L	1446	Missense	distal	-6	no	16.299	15.663	EPSD;PhosphoSitePlus	ICGC;COSMIC;GDSC	15.080	Down-regulation
TKL_LRRK_LRRK2_ST	Q5S007	LRRK2	Q5S007	LRRK2	S1457	E1459K	1459	Missense	proximal	2	no	16.050	16.788	EPSD;PhosphoSitePlus	ICGC	15.080	Up-regulation
TKL_LRRK_LRRK2_ST	Q5S007	LRRK2	Q5S007	LRRK2	S1457	D1458Y	1458	Missense	proximal	1	no	16.050	16.200	EPSD;PhosphoSitePlus	ICGC	15.080	Up-regulation
TKL_LRRK_LRRK2_ST	Q5S007	LRRK2	Q5S007	LRRK2	S1457	V1456F	1456	Missense	proximal	-1	no	16.050	16.390	EPSD;PhosphoSitePlus	ICGC	15.080	Up-regulation
TKL_LRRK_LRRK2_ST	Q5S007	LRRK2	Q5S007	LRRK2	S1457	R1462L	1462	Missense	distal	5	no	16.050	15.836	EPSD;PhosphoSitePlus	ICGC	15.080	Down-regulation
TKL_LRRK_LRRK2_ST	Q5S007	LRRK2	Q5S007	LRRK2	S1467	R1462L	1462	Missense	distal	-5	no	16.764	16.598	EPSD;PhosphoSitePlus	ICGC	15.080	Down-regulation
TKL_LRRK_LRRK2_ST	Q5S007	LRRK2	Q5S007	LRRK2	S1467	E1472V	1472	Missense	distal	5	no	16.764	17.177	EPSD;PhosphoSitePlus	ICGC	15.080	Up-regulation
TKL_LRRK_LRRK2_ST	Q5S007	LRRK2	Q5S007	LRRK2	T1470	R1477P	1477	Missense	distal	7	no	16.915	16.969	EPSD;PhosphoSitePlus	ICGC;COSMIC	15.080	Up-regulation
TKL_LRRK_LRRK2_ST	Q5S007	LRRK2	Q5S007	LRRK2	T1470	E1472V	1472	Missense	proximal	2	no	16.915	16.930	EPSD;PhosphoSitePlus	ICGC	15.080	Up-regulation
TKL_LRRK_LRRK2_ST	Q5S007	LRRK2	Q5S007	LRRK2	T1491	A1490V	1490	Missense	proximal	-1	no	17.116	15.999	EPSD;PhosphoSitePlus	ICGC;COSMIC	15.080	Down-regulation
TKL_LRRK_LRRK2_ST	Q5S007	LRRK2	Q5S007	LRRK2	T1491	A1490T	1490	Missense	proximal	-1	no	17.116	16.500	EPSD;PhosphoSitePlus	ICGC;COSMIC	15.080	Down-regulation
TKL_LRRK_LRRK2_ST	Q5S007	LRRK2	Q5S007	LRRK2	T1491	A1496V	1496	Missense	distal	5	no	17.116	17.449	EPSD;PhosphoSitePlus	ICGC	15.080	Up-regulation
TKL_LRRK_LRRK2_ST	Q5S007	LRRK2	Q5S007	LRRK2	T1491	D1495G	1495	Missense	distal	4	no	17.116	17.570	EPSD;PhosphoSitePlus	ICGC;COSMIC	15.080	Up-regulation
TKL_LRRK_LRRK2_ST	Q5S007	LRRK2	Q5S007	LRRK2	T1503	A1496V	1496	Missense	distal	-7	no	16.958	17.096	EPSD;PhosphoSitePlus	ICGC	15.080	Up-regulation
TKL_LRRK_LRRK2_ST	Q5S007	LRRK2	Q5S007	LRRK2	T1503	R1501Q	1501	Missense	proximal	-2	no	16.958	16.748	EPSD;PhosphoSitePlus	ICGC;COSMIC	15.080	Down-regulation
TKL_LRRK_LRRK2_ST	Q5S007	LRRK2	Q5S007	LRRK2	S1508	R1501Q	1501	Missense	distal	-7	no	16.245	15.719	EPSD;PhosphoSitePlus	ICGC;COSMIC	15.080	Down-regulation
TKL_LRRK_LRRK2_ST	Q5S007	LRRK2	Q5S007	LRRK2	S1536	K1532T	1532	Missense	distal	-4	no	16.428	15.820	EPSD;PhosphoSitePlus	ICGC	15.080	Down-regulation
TKL_LRRK_LRRK2_ST	Q5S007	LRRK2	Q5S007	LRRK2	S1536	R1538H	1538	Missense	proximal	2	no	16.428	16.016	EPSD;PhosphoSitePlus	ICGC;COSMIC	15.080	Down-regulation
TKL_LRRK_LRRK2_ST	Q5S007	LRRK2	Q5S007	LRRK2	S1536	E1531D	1531	Missense	distal	-5	no	16.428	16.288	EPSD;PhosphoSitePlus	ICGC;COSMIC	15.080	Down-regulation
TKL_LRRK_LRRK2_ST	Q5S007	LRRK2	Q5S007	LRRK2	S1536	R1538C	1538	Missense	proximal	2	no	16.428	15.879	EPSD;PhosphoSitePlus	ICGC;COSMIC;GDSC;CCLE	15.080	Down-regulation
TKL_LRRK_LRRK2_ST	Q5S007	LRRK2	Q5S007	LRRK2	S1536	S1536L	1536	Missense	central	0	yes	16.428	0.000	EPSD;PhosphoSitePlus	ICGC;COSMIC	15.080	Loss
TKL_LRRK_LRRK2_ST	Q5S007	LRRK2	Q5S007	LRRK2	S1536	E1529K	1529	Missense	distal	-7	no	16.428	17.843	EPSD;PhosphoSitePlus	ICGC	15.080	Up-regulation
TKL_LRRK_LRRK2_ST	Q5S007	LRRK2	Q5S007	LRRK2	T1612	K1614E	1614	Missense	proximal	2	no	19.531	18.793	EPSD;PhosphoSitePlus	ICGC	15.080	Down-regulation
TKL_LRRK_LRRK2_ST	Q5S007	LRRK2	Q5S007	LRRK2	T1612	G1617V	1617	Missense	distal	5	no	19.531	20.103	EPSD;PhosphoSitePlus	ICGC;COSMIC	15.080	Up-regulation
TKL_LRRK_LRRK2_ST	Q5S007	LRRK2	Q5S007	LRRK2	T1612	M1607I	1607	Missense	distal	-5	no	19.531	19.491	EPSD;PhosphoSitePlus	ICGC	15.080	Down-regulation
TKL_LRRK_LRRK2_ST	Q5S007	LRRK2	Q5S007	LRRK2	S1647	Y1649S	1649	Missense	proximal	2	no	16.945	17.397	EPSD;PhosphoSitePlus	ICGC;COSMIC	15.080	Up-regulation
TKL_LRRK_LRRK2_ST	Q5S007	LRRK2	Q5S007	LRRK2	S1721	G1722W	1722	Missense	proximal	1	no	15.528	15.021	EPSD	ICGC;COSMIC	15.080	Loss
TKL_LRRK_LRRK2_ST	Q5S007	LRRK2	Q5S007	LRRK2	T1912	F1908C	1908	Missense	distal	-4	no	17.371	16.109	EPSD;PhosphoSitePlus	ICGC;COSMIC	15.080	Down-regulation
TKL_LRRK_LRRK2_ST	Q5S007	LRRK2	Q5S007	LRRK2	S1913	F1908C	1908	Missense	distal	-5	no	19.825	19.848	EPSD;PhosphoSitePlus	ICGC;COSMIC	15.080	Up-regulation
TKL_LRRK_LRRK2_ST	Q5S007	LRRK2	Q5S007	LRRK2	T1967	T1969P	1969	Missense	proximal	2	no	17.155	16.121	EPSD;PhosphoSitePlus	ICGC	15.080	Down-regulation
TKL_LRRK_LRRK2_ST	Q5S007	LRRK2	Q5S007	LRRK2	T1967	S1965N	1965	Missense	proximal	-2	no	17.155	17.176	EPSD;PhosphoSitePlus	ICGC;COSMIC;CCLE	15.080	Up-regulation
TKL_LRRK_LRRK2_ST	Q5S007	LRRK2	Q5S007	LRRK2	T1967	L1970V	1970	Missense	distal	3	no	17.155	17.037	EPSD;PhosphoSitePlus	ICGC;COSMIC	15.080	Down-regulation
TKL_LRRK_LRRK2_ST	Q5S007	LRRK2	Q5S007	LRRK2	T1967	L1970I	1970	Missense	distal	3	no	17.155	17.154	EPSD;PhosphoSitePlus	ICGC;COSMIC	15.080	Down-regulation
TKL_LRRK_LRRK2_ST	Q5S007	LRRK2	Q5S007	LRRK2	T1969	T1969P	1969	Missense	central	0	yes	18.241	0.000	EPSD;PhosphoSitePlus	ICGC	15.080	Loss
TKL_LRRK_LRRK2_ST	Q5S007	LRRK2	Q5S007	LRRK2	T1969	S1965N	1965	Missense	distal	-4	no	18.241	19.096	EPSD;PhosphoSitePlus	ICGC;COSMIC;CCLE	15.080	Up-regulation
TKL_LRRK_LRRK2_ST	Q5S007	LRRK2	Q5S007	LRRK2	T1969	L1970V	1970	Missense	proximal	1	no	18.241	18.015	EPSD;PhosphoSitePlus	ICGC;COSMIC	15.080	Down-regulation
TKL_LRRK_LRRK2_ST	Q5S007	LRRK2	Q5S007	LRRK2	T1969	L1970I	1970	Missense	proximal	1	no	18.241	18.193	EPSD;PhosphoSitePlus	ICGC;COSMIC	15.080	Down-regulation
TKL_LRRK_LRRK2_ST	Q5S007	LRRK2	Q5S007	LRRK2	T2031	F2038V	2038	Missense	distal	7	no	18.012	17.960	PhosphoSitePlus;EPSD	ICGC	15.080	Down-regulation
TKL_LRRK_LRRK2_ST	Q5S007	LRRK2	Q5S007	LRRK2	T2031	C2024Y	2024	Missense	distal	-7	no	18.012	17.590	PhosphoSitePlus;EPSD	ICGC;COSMIC	15.080	Down-regulation
TKL_LRRK_LRRK2_ST	Q5S007	LRRK2	Q5S007	LRRK2	T2031	G2034C	2034	Missense	distal	3	no	18.012	18.050	PhosphoSitePlus;EPSD	ICGC;COSMIC	15.080	Up-regulation
TKL_LRRK_LRRK2_ST	Q5S007	LRRK2	Q5S007	LRRK2	T2031	P2036Q	2036	Missense	distal	5	no	18.012	17.111	PhosphoSitePlus;EPSD	ICGC;COSMIC	15.080	Down-regulation
TKL_LRRK_LRRK2_ST	Q5S007	LRRK2	Q5S007	LRRK2	T2031	G2028W	2028	Missense	distal	-3	no	18.012	18.522	PhosphoSitePlus;EPSD	ICGC;COSMIC	15.080	Up-regulation
TKL_LRRK_LRRK2_ST	Q5S007	LRRK2	Q5S007	LRRK2	S2032	P2036Q	2036	Missense	distal	4	no	14.382	15.833	EPSD;PhosphoSitePlus	ICGC;COSMIC	15.080	Gain
TKL_LRRK_LRRK2_ST	Q5S007	LRRK2	Q5S007	LRRK2	T2035	F2038V	2038	Missense	distal	3	no	16.598	16.449	EPSD;PhosphoSitePlus	ICGC	15.080	Down-regulation
TKL_LRRK_LRRK2_ST	Q5S007	LRRK2	Q5S007	LRRK2	T2035	G2034C	2034	Missense	proximal	-1	no	16.598	14.610	EPSD;PhosphoSitePlus	ICGC;COSMIC	15.080	Loss
TKL_LRRK_LRRK2_ST	Q5S007	LRRK2	Q5S007	LRRK2	T2035	P2036Q	2036	Missense	proximal	1	no	16.598	16.490	EPSD;PhosphoSitePlus	ICGC;COSMIC	15.080	Down-regulation
TKL_LRRK_LRRK2_ST	Q5S007	LRRK2	Q5S007	LRRK2	T2035	G2028W	2028	Missense	distal	-7	no	16.598	15.222	EPSD;PhosphoSitePlus	ICGC;COSMIC	15.080	Down-regulation
TKL_LRRK_LRRK2_ST	Q5S007	LRRK2	Q5S007	LRRK2	S2257	C2250W	2250	Missense	distal	-7	no	17.369	16.306	EPSD;PhosphoSitePlus	ICGC;COSMIC	15.080	Down-regulation
TKL_LRRK_LRRK2_ST	Q5S007	LRRK2	Q5S007	LRRK2	S2257	C2250F	2250	Missense	distal	-7	no	17.369	17.532	EPSD;PhosphoSitePlus	ICGC;COSMIC	15.080	Up-regulation
TKL_LRRK_LRRK2_ST	Q5S007	LRRK2	Q5S007	LRRK2	T2460	S2454W	2454	Missense	distal	-6	no	14.172	16.154	EPSD	ICGC;COSMIC	15.080	Gain
TKL_LRRK_LRRK2_ST	Q5S007	LRRK2	Q5S007	LRRK2	T2483	I2489M	2489	Missense	distal	6	no	19.727	19.578	EPSD;PhosphoSitePlus	ICGC	15.080	Down-regulation
TKL_LRRK_LRRK2_ST	O75061	DNAJC6	Q5S007	LRRK2	S563	R561T	561	Missense	proximal	-2	no	15.673	15.254	EPSD	ICGC	15.080	Down-regulation
TKL_LRRK_LRRK2_ST	O75061	DNAJC6	Q5S007	LRRK2	S563	R561I	561	Missense	proximal	-2	no	15.673	15.556	EPSD	ICGC	15.080	Down-regulation
TKL_LRRK_LRRK2_ST	P04637	TP53	Q5S007	LRRK2	T304	H297Q	297	Missense	distal	-7	no	17.200	17.377	EPSD;PhosphoSitePlus	ICGC	15.080	Up-regulation
TKL_LRRK_LRRK2_ST	P04637	TP53	Q5S007	LRRK2	T304	P301T	301	Missense	distal	-3	no	17.200	16.979	EPSD;PhosphoSitePlus	ICGC;COSMIC	15.080	Down-regulation
TKL_LRRK_LRRK2_ST	P04637	TP53	Q5S007	LRRK2	T377	T377P	377	Missense	central	0	yes	15.470	0.000	PhosphoSitePlus;EPSD	ICGC;COSMIC	15.080	Loss
TKL_LRRK_LRRK2_ST	P04637	TP53	Q5S007	LRRK2	T377	G374C	374	Missense	distal	-3	no	15.470	15.616	PhosphoSitePlus;EPSD	ICGC;COSMIC	15.080	Up-regulation
TKL_LRRK_LRRK2_ST	P04637	TP53	Q5S007	LRRK2	T377	R379S	379	Missense	proximal	2	no	15.470	14.691	PhosphoSitePlus;EPSD	ICGC	15.080	Loss
TKL_LRRK_LRRK2_ST	P04637	TP53	Q5S007	LRRK2	T377	R379C	379	Missense	proximal	2	no	15.470	14.920	PhosphoSitePlus;EPSD	ICGC;COSMIC	15.080	Loss
TKL_LRRK_LRRK2_ST	P62280	RPS11	Q5S007	LRRK2	T28	K32N	32	Missense	distal	4	no	16.306	16.428	EPSD;PhosphoSitePlus	ICGC	15.080	Up-regulation
TKL_LRRK_LRRK2_ST	P62280	RPS11	Q5S007	LRRK2	T28	V23F	23	Missense	distal	-5	no	16.306	16.392	EPSD;PhosphoSitePlus	ICGC	15.080	Up-regulation
TKL_LRRK_LRRK2_ST	P62280	RPS11	Q5S007	LRRK2	T28	P34S	34	Missense	distal	6	no	16.306	16.547	EPSD;PhosphoSitePlus	ICGC	15.080	Up-regulation
TKL_LRRK_LRRK2_ST	P62280	RPS11	Q5S007	LRRK2	T46	E52Q	52	Missense	distal	6	no	18.909	19.399	PhosphoSitePlus;EPSD	ICGC;COSMIC	15.080	Up-regulation
TKL_LRRK_LRRK2_ST	P62280	RPS11	Q5S007	LRRK2	T46	G43C	43	Missense	distal	-3	no	18.909	19.055	PhosphoSitePlus;EPSD	ICGC	15.080	Up-regulation
TKL_LRRK_LRRK2_ST	P62280	RPS11	Q5S007	LRRK2	T54	E52Q	52	Missense	proximal	-2	no	18.314	18.417	EPSD;PhosphoSitePlus	ICGC;COSMIC	15.080	Up-regulation
TKL_LRRK_LRRK2_ST	P62280	RPS11	Q5S007	LRRK2	T78	R71L	71	Missense	distal	-7	no	15.774	14.145	EPSD	ICGC	15.080	Loss
TKL_LRRK_LRRK2_ST	P26038	MSN	Q5S007	LRRK2	T413	L417Q	417	Missense	distal	4	no	14.935	15.112	EPSD	ICGC;COSMIC	15.080	Gain
TKL_LRRK_LRRK2_ST	P26038	MSN	Q5S007	LRRK2	T539	M543I	543	Missense	distal	4	no	15.538	15.787	EPSD	ICGC	15.080	Up-regulation
TKL_LRRK_LRRK2_ST	P10636	MAPT	Q5S007	LRRK2	T111	D116E	116	Missense	distal	5	no	17.258	16.845	EPSD	ICGC;COSMIC	15.080	Down-regulation
TKL_LRRK_LRRK2_ST	P10636	MAPT	Q5S007	LRRK2	S420	S427F	427	Missense	distal	7	no	15.236	15.260	EPSD	ICGC	15.080	Up-regulation
TKL_LRRK_LRRK2_ST	P10636	MAPT	Q5S007	LRRK2	S447	Y441H	441	Missense	distal	-6	no	15.455	13.123	EPSD	ICGC;COSMIC	15.080	Loss
TKL_LRRK_LRRK2_ST	P10636	MAPT	Q5S007	LRRK2	T522	G521R	521	Missense	proximal	-1	no	17.917	18.228	EPSD	ICGC;COSMIC	15.080	Up-regulation
TKL_LRRK_LRRK2_ST	P05067	APP	Q5S007	LRRK2	T381	E385Q	385	Missense	distal	4	no	16.467	16.145	EPSD	ICGC;COSMIC	15.080	Down-regulation
TKL_LRRK_LRRK2_ST	P05067	APP	Q5S007	LRRK2	S441	Q436H	436	Missense	distal	-5	no	16.391	16.128	EPSD	ICGC;COSMIC	15.080	Down-regulation
TKL_LRRK_LRRK2_ST	Q13501	SQSTM1	Q5S007	LRRK2	S88	D93Y	93	Missense	distal	5	no	16.466	16.032	EPSD	ICGC;COSMIC	15.080	Down-regulation
TKL_LRRK_LRRK2_ST	Q13501	SQSTM1	Q5S007	LRRK2	T138	G137A	137	Missense	proximal	-1	no	15.898	15.425	PhosphoSitePlus	ICGC;COSMIC	15.080	Down-regulation
TKL_LRRK_LRRK2_ST	Q13501	SQSTM1	Q5S007	LRRK2	T138	R139L	139	Missense	proximal	1	no	15.898	15.867	PhosphoSitePlus	ICGC	15.080	Down-regulation
TKL_LRRK_LRRK2_ST	Q13501	SQSTM1	Q5S007	LRRK2	T138	T138I	138	Missense	central	0	yes	15.898	0.000	PhosphoSitePlus	ICGC;COSMIC	15.080	Loss
TKL_LRRK_LRRK2_ST	Q13501	SQSTM1	Q5S007	LRRK2	T138	G137E	137	Missense	proximal	-1	no	15.898	14.037	PhosphoSitePlus	ICGC	15.080	Loss
TKL_LRRK_LRRK2_ST	Q13501	SQSTM1	Q5S007	LRRK2	T138	V135A	135	Missense	distal	-3	no	15.898	15.938	PhosphoSitePlus	ICGC;COSMIC	15.080	Up-regulation
TKL_LRRK_LRRK2_ST	Q13501	SQSTM1	Q5S007	LRRK2	T164	K165R	165	Missense	proximal	1	no	17.232	17.168	EPSD	ICGC;COSMIC	15.080	Down-regulation
TKL_LRRK_LRRK2_ST	Q13501	SQSTM1	Q5S007	LRRK2	T164	K157Q	157	Missense	distal	-7	no	17.232	16.204	EPSD	ICGC;COSMIC	15.080	Down-regulation
TKL_LRRK_LRRK2_ST	Q13501	SQSTM1	Q5S007	LRRK2	T164	A167E	167	Missense	distal	3	no	17.232	17.169	EPSD	ICGC	15.080	Down-regulation
TKL_LRRK_LRRK2_ST	Q13501	SQSTM1	Q5S007	LRRK2	T164	K165N	165	Missense	proximal	1	no	17.232	16.944	EPSD	ICGC	15.080	Down-regulation
TKL_LRRK_LRRK2_ST	Q13501	SQSTM1	Q5S007	LRRK2	T221	G219D	219	Missense	proximal	-2	no	15.108	14.766	EPSD	ICGC	15.080	Loss
CAMK_CAMKL_QIK_SIK1_ST	Q9Y618	NCOR2	P57059	SIK1	S67	P74L	74	Missense	distal	7	no	10.104	9.327	EPSD	ICGC;COSMIC	6.412	Down-regulation
CAMK_CAMKL_QIK_SIK1_ST	Q9Y618	NCOR2	P57059	SIK1	S67	Q60K	60	Missense	distal	-7	no	10.104	9.909	EPSD	ICGC	6.412	Down-regulation
CAMK_CAMKL_QIK_SIK1_ST	Q9Y618	NCOR2	P57059	SIK1	S67	P74T	74	Missense	distal	7	no	10.104	10.258	EPSD	ICGC	6.412	Up-regulation
CAMK_CAMKL_QIK_SIK1_ST	Q9Y618	NCOR2	P57059	SIK1	S88	P93L	93	Missense	distal	5	no	7.042	6.922	EPSD	ICGC;COSMIC	6.412	Down-regulation
CAMK_CAMKL_QIK_SIK1_ST	Q9Y618	NCOR2	P57059	SIK1	S88	H83Q	83	Missense	distal	-5	no	7.042	7.565	EPSD	ICGC	6.412	Up-regulation
CAMK_CAMKL_QIK_SIK1_ST	Q9Y618	NCOR2	P57059	SIK1	S98	P93L	93	Missense	distal	-5	no	4.984	7.292	EPSD	ICGC;COSMIC	6.412	Gain
CAMK_CAMKL_QIK_SIK1_ST	Q9Y618	NCOR2	P57059	SIK1	S140	T136N	136	Missense	distal	-4	no	6.096	6.511	EPSD	ICGC	6.412	Gain
CAMK_CAMKL_QIK_SIK1_ST	Q9Y618	NCOR2	P57059	SIK1	S433	R426S	426	Missense	distal	-7	no	7.081	7.091	EPSD	ICGC;COSMIC	6.412	Up-regulation
CAMK_CAMKL_QIK_SIK1_ST	Q9Y618	NCOR2	P57059	SIK1	S433	Q427R	427	Missense	distal	-6	no	7.081	7.121	EPSD	ICGC;COSMIC	6.412	Up-regulation
CAMK_CAMKL_QIK_SIK1_ST	Q9Y618	NCOR2	P57059	SIK1	S1018	S1025P	1025	Missense	distal	7	no	9.929	9.398	EPSD	ICGC	6.412	Down-regulation
CAMK_CAMKL_QIK_SIK1_ST	Q9Y618	NCOR2	P57059	SIK1	S1487	P1493L	1493	Missense	distal	6	no	6.600	6.170	EPSD	ICGC	6.412	Loss
CAMK_CAMKL_QIK_SIK1_ST	Q9Y618	NCOR2	P57059	SIK1	S1547	G1542D	1542	Missense	distal	-5	no	6.156	7.186	EPSD	ICGC;COSMIC	6.412	Gain
CAMK_CAMKL_QIK_SIK1_ST	Q9Y618	NCOR2	P57059	SIK1	S1584	S1585F	1585	Missense	proximal	1	no	6.464	5.929	EPSD	ICGC;COSMIC	6.412	Loss
CAMK_CAMKL_QIK_SIK1_ST	Q9Y618	NCOR2	P57059	SIK1	S1606	P1613T	1613	Missense	distal	7	no	9.032	9.185	EPSD	ICGC	6.412	Up-regulation
CAMK_CAMKL_QIK_SIK1_ST	Q9Y618	NCOR2	P57059	SIK1	S1726	R1719Q	1719	Missense	distal	-7	no	7.332	7.478	EPSD	ICGC	6.412	Up-regulation
CAMK_CAMKL_QIK_SIK1_ST	Q9Y618	NCOR2	P57059	SIK1	S1783	S1782F	1782	Missense	proximal	-1	no	8.658	8.380	EPSD	ICGC;COSMIC	6.412	Down-regulation
CAMK_CAMKL_QIK_SIK1_ST	Q9Y618	NCOR2	P57059	SIK1	S2189	P2196T	2196	Missense	distal	7	no	8.889	9.043	EPSD	ICGC	6.412	Up-regulation
CMGC_MAPK_p38_MAPK14_ST	P49023	PXN	Q16539	MAPK14	S230	S226T	226	Missense	distal	-4	no	10.238	10.515	EPSD	ICGC;COSMIC	5.915	Up-regulation
CMGC_MAPK_p38_MAPK14_ST	P49023	PXN	Q16539	MAPK14	S322	S322L	322	Missense	central	0	yes	10.603	0.000	EPSD	ICGC;COSMIC	5.915	Loss
CMGC_MAPK_p38_MAPK14_ST	P49023	PXN	Q16539	MAPK14	S322	P328L	328	Missense	distal	6	no	10.603	10.464	EPSD	ICGC	5.915	Down-regulation
CMGC_MAPK_p38_MAPK14_ST	Q02078	MEF2A	Q16539	MAPK14	S98	Y105C	105	Missense	distal	7	no	10.930	10.322	EPSD;PhosphoSitePlus	ICGC;COSMIC	5.915	Down-regulation
CMGC_MAPK_p38_MAPK14_ST	Q02078	MEF2A	Q16539	MAPK14	S98	P99S	99	Missense	proximal	1	no	10.930	3.646	EPSD;PhosphoSitePlus	ICGC;COSMIC	5.915	Loss
CMGC_MAPK_p38_MAPK14_ST	Q02078	MEF2A	Q16539	MAPK14	S98	D102E	102	Missense	distal	4	no	10.930	12.599	EPSD;PhosphoSitePlus	ICGC;COSMIC	5.915	Up-regulation
CMGC_MAPK_p38_MAPK14_ST	Q02078	MEF2A	Q16539	MAPK14	S98	D97N	97	Missense	proximal	-1	no	10.930	10.744	EPSD;PhosphoSitePlus	ICGC	5.915	Down-regulation
CMGC_MAPK_p38_MAPK14_ST	Q02078	MEF2A	Q16539	MAPK14	T108	H110Y	110	Missense	proximal	2	no	12.793	12.996	EPSD;PhosphoSitePlus	ICGC;COSMIC	5.915	Up-regulation
CMGC_MAPK_p38_MAPK14_ST	Q02078	MEF2A	Q16539	MAPK14	T108	Y105C	105	Missense	distal	-3	no	12.793	12.005	EPSD;PhosphoSitePlus	ICGC;COSMIC	5.915	Down-regulation
CMGC_MAPK_p38_MAPK14_ST	Q02078	MEF2A	Q16539	MAPK14	T108	V106L	106	Missense	proximal	-2	no	12.793	12.491	EPSD;PhosphoSitePlus	ICGC	5.915	Down-regulation
CMGC_MAPK_p38_MAPK14_ST	Q02078	MEF2A	Q16539	MAPK14	T108	E112D	112	Missense	distal	4	no	12.793	11.124	EPSD;PhosphoSitePlus	ICGC	5.915	Down-regulation
CMGC_MAPK_p38_MAPK14_ST	Q02078	MEF2A	Q16539	MAPK14	T108	D102E	102	Missense	distal	-6	no	12.793	13.372	EPSD;PhosphoSitePlus	ICGC;COSMIC	5.915	Up-regulation
CMGC_MAPK_p38_MAPK14_ST	Q02078	MEF2A	Q16539	MAPK14	S181	D176Y	176	Missense	distal	-5	no	13.783	13.608	EPSD	ICGC	5.915	Down-regulation
CMGC_MAPK_p38_MAPK14_ST	Q02078	MEF2A	Q16539	MAPK14	S192	P196F	196	Missense	distal	4	no	11.537	10.402	PhosphoSitePlus;EPSD	ICGC	5.915	Down-regulation
CMGC_MAPK_p38_MAPK14_ST	Q02078	MEF2A	Q16539	MAPK14	S192	P196L	196	Missense	distal	4	no	11.537	10.898	PhosphoSitePlus;EPSD	ICGC	5.915	Down-regulation
CMGC_MAPK_p38_MAPK14_ST	Q02078	MEF2A	Q16539	MAPK14	S201	M208I	208	Missense	distal	7	no	7.387	6.784	EPSD	ICGC	5.915	Down-regulation
CMGC_MAPK_p38_MAPK14_ST	Q02078	MEF2A	Q16539	MAPK14	S201	P196F	196	Missense	distal	-5	no	7.387	7.724	EPSD	ICGC	5.915	Up-regulation
CMGC_MAPK_p38_MAPK14_ST	Q02078	MEF2A	Q16539	MAPK14	S201	P196L	196	Missense	distal	-5	no	7.387	7.668	EPSD	ICGC	5.915	Up-regulation
CMGC_MAPK_p38_MAPK14_ST	Q02078	MEF2A	Q16539	MAPK14	S223	G226E	226	Missense	distal	3	no	11.196	11.150	EPSD;PhosphoSitePlus	ICGC;COSMIC	5.915	Down-regulation
CMGC_MAPK_p38_MAPK14_ST	Q02078	MEF2A	Q16539	MAPK14	S223	A220S	220	Missense	distal	-3	no	11.196	11.608	EPSD;PhosphoSitePlus	ICGC;COSMIC	5.915	Up-regulation
CMGC_MAPK_p38_MAPK14_ST	Q02078	MEF2A	Q16539	MAPK14	S235	R233K	233	Missense	proximal	-2	no	11.534	10.931	EPSD	ICGC;COSMIC	5.915	Down-regulation
CMGC_MAPK_p38_MAPK14_ST	Q02078	MEF2A	Q16539	MAPK14	S255	M251V	251	Missense	distal	-4	no	10.492	10.743	EPSD	ICGC;COSMIC	5.915	Up-regulation
CMGC_MAPK_p38_MAPK14_ST	Q02078	MEF2A	Q16539	MAPK14	T415	Q422P	422	Missense	distal	7	no	7.415	7.352	EPSD	ICGC;COSMIC	5.915	Down-regulation
CMGC_MAPK_p38_MAPK14_ST	P04150	NR3C1	Q16539	MAPK14	T8	E13Q	13	Missense	distal	5	no	12.176	11.554	EPSD	ICGC;COSMIC	5.915	Down-regulation
CMGC_MAPK_p38_MAPK14_ST	P04150	NR3C1	Q16539	MAPK14	T8	S3F	3	Missense	distal	-5	no	12.176	12.961	EPSD	ICGC	5.915	Up-regulation
CMGC_MAPK_p38_MAPK14_ST	P04150	NR3C1	Q16539	MAPK14	S45	A49D	49	Missense	distal	4	no	10.868	10.004	EPSD	ICGC	5.915	Down-regulation
CMGC_MAPK_p38_MAPK14_ST	P04150	NR3C1	Q16539	MAPK14	S47	A49D	49	Missense	proximal	2	no	7.746	7.524	EPSD	ICGC	5.915	Down-regulation
CMGC_MAPK_p38_MAPK14_ST	P04150	NR3C1	Q16539	MAPK14	T133	N138K	138	Missense	distal	5	no	6.481	6.212	EPSD	ICGC	5.915	Down-regulation
CMGC_MAPK_p38_MAPK14_ST	P04150	NR3C1	Q16539	MAPK14	T133	R131M	131	Missense	proximal	-2	no	6.481	6.358	EPSD	ICGC;COSMIC	5.915	Down-regulation
CMGC_MAPK_p38_MAPK14_ST	P04150	NR3C1	Q16539	MAPK14	S144	N138K	138	Missense	distal	-6	no	6.120	5.958	EPSD	ICGC	5.915	Down-regulation
CMGC_MAPK_p38_MAPK14_ST	P04150	NR3C1	Q16539	MAPK14	S226	E221K	221	Missense	distal	-5	no	9.180	9.514	EPSD;PhosphoSitePlus	ICGC;COSMIC	5.915	Up-regulation
CMGC_MAPK_p38_MAPK14_ST	P04150	NR3C1	Q16539	MAPK14	S226	E231K	231	Missense	distal	5	no	9.180	8.613	EPSD;PhosphoSitePlus	ICGC;COSMIC	5.915	Down-regulation
CMGC_MAPK_p38_MAPK14_ST	P04150	NR3C1	Q16539	MAPK14	S234	L236F	236	Missense	proximal	2	no	6.277	6.100	EPSD	ICGC	5.915	Down-regulation
CMGC_MAPK_p38_MAPK14_ST	P04150	NR3C1	Q16539	MAPK14	S234	E231K	231	Missense	distal	-3	no	6.277	5.885	EPSD	ICGC;COSMIC	5.915	Loss
CMGC_MAPK_p38_MAPK14_ST	P04150	NR3C1	Q16539	MAPK14	S267	S269G	269	Missense	proximal	2	no	10.514	10.286	EPSD	ICGC	5.915	Down-regulation
CMGC_MAPK_p38_MAPK14_ST	P04150	NR3C1	Q16539	MAPK14	S267	S269N	269	Missense	proximal	2	no	10.514	10.258	EPSD	ICGC;COSMIC	5.915	Down-regulation
CMGC_MAPK_p38_MAPK14_ST	P04150	NR3C1	Q16539	MAPK14	S404	T411S	411	Missense	distal	7	no	10.424	10.745	EPSD	ICGC;COSMIC	5.915	Up-regulation
CMGC_MAPK_p38_MAPK14_ST	P04150	NR3C1	Q16539	MAPK14	S407	T411S	411	Missense	distal	4	no	5.663	5.924	EPSD	ICGC;COSMIC	5.915	Gain
CMGC_MAPK_p38_MAPK14_ST	P04150	NR3C1	Q16539	MAPK14	S410	T411S	411	Missense	proximal	1	no	7.787	7.956	EPSD	ICGC;COSMIC	5.915	Up-regulation
CMGC_MAPK_p38_MAPK14_ST	P19634	SLC9A1	Q16539	MAPK14	S11	G6D	6	Missense	distal	-5	no	9.503	9.745	EPSD	ICGC;COSMIC	5.915	Up-regulation
CMGC_MAPK_p38_MAPK14_ST	P19634	SLC9A1	Q16539	MAPK14	S11	I7V	7	Missense	distal	-4	no	9.503	9.658	EPSD	ICGC;COSMIC	5.915	Up-regulation
CMGC_MAPK_p38_MAPK14_ST	P19634	SLC9A1	Q16539	MAPK14	T68	P69Q	69	Missense	proximal	1	no	12.510	5.302	EPSD	ICGC	5.915	Loss
CMGC_MAPK_p38_MAPK14_ST	P19634	SLC9A1	Q16539	MAPK14	T68	S71I	71	Missense	distal	3	no	12.510	12.606	EPSD	ICGC;COSMIC	5.915	Up-regulation
CMGC_MAPK_p38_MAPK14_ST	P19634	SLC9A1	Q16539	MAPK14	S693	H689Q	689	Missense	distal	-4	no	10.047	10.204	EPSD	ICGC	5.915	Up-regulation
CMGC_MAPK_p38_MAPK14_ST	P19634	SLC9A1	Q16539	MAPK14	S693	P687T	687	Missense	distal	-6	no	10.047	10.381	EPSD	ICGC	5.915	Up-regulation
CMGC_MAPK_p38_MAPK14_ST	P19634	SLC9A1	Q16539	MAPK14	S693	R700S	700	Missense	distal	7	no	10.047	10.013	EPSD	ICGC	5.915	Down-regulation
CMGC_MAPK_p38_MAPK14_ST	P19634	SLC9A1	Q16539	MAPK14	S703	G702S	702	Missense	proximal	-1	no	6.509	6.296	EPSD	ICGC;COSMIC	5.915	Down-regulation
CMGC_MAPK_p38_MAPK14_ST	P19634	SLC9A1	Q16539	MAPK14	S703	R700S	700	Missense	distal	-3	no	6.509	5.997	EPSD	ICGC	5.915	Down-regulation
CMGC_MAPK_p38_MAPK14_ST	Q09472	EP300	Q16539	MAPK14	S20	S24L	24	Missense	distal	4	no	10.459	9.380	EPSD	ICGC;COSMIC	5.915	Down-regulation
CMGC_MAPK_p38_MAPK14_ST	Q09472	EP300	Q16539	MAPK14	S24	S24L	24	Missense	central	0	yes	6.820	0.000	EPSD	ICGC;COSMIC	5.915	Loss
CMGC_MAPK_p38_MAPK14_ST	Q09472	EP300	Q16539	MAPK14	S28	S24L	24	Missense	distal	-4	no	5.460	6.060	EPSD	ICGC;COSMIC	5.915	Gain
CMGC_MAPK_p38_MAPK14_ST	Q09472	EP300	Q16539	MAPK14	S89	L93F	93	Missense	distal	4	no	8.000	7.504	EPSD	ICGC	5.915	Down-regulation
CMGC_MAPK_p38_MAPK14_ST	Q09472	EP300	Q16539	MAPK14	S90	L93F	93	Missense	distal	3	no	10.176	10.211	EPSD	ICGC	5.915	Up-regulation
CMGC_MAPK_p38_MAPK14_ST	Q09472	EP300	Q16539	MAPK14	S112	S106C	106	Missense	distal	-6	no	9.094	7.802	EPSD	ICGC;COSMIC	5.915	Down-regulation
CMGC_MAPK_p38_MAPK14_ST	Q09472	EP300	Q16539	MAPK14	S227	Q224H	224	Missense	distal	-3	no	9.886	9.911	EPSD	ICGC	5.915	Up-regulation
CMGC_MAPK_p38_MAPK14_ST	Q09472	EP300	Q16539	MAPK14	S227	G226V	226	Missense	proximal	-1	no	9.886	9.889	EPSD	ICGC	5.915	Up-regulation
CMGC_MAPK_p38_MAPK14_ST	Q09472	EP300	Q16539	MAPK14	S285	P286L	286	Missense	proximal	1	no	11.201	3.150	EPSD	ICGC	5.915	Loss
CMGC_MAPK_p38_MAPK14_ST	Q09472	EP300	Q16539	MAPK14	T317	A320S	320	Missense	distal	3	no	9.145	9.130	EPSD	ICGC;COSMIC	5.915	Down-regulation
CMGC_MAPK_p38_MAPK14_ST	Q09472	EP300	Q16539	MAPK14	S831	R838C	838	Missense	distal	7	no	9.403	8.803	EPSD	ICGC;COSMIC	5.915	Down-regulation
CMGC_MAPK_p38_MAPK14_ST	Q09472	EP300	Q16539	MAPK14	S831	L827R	827	Missense	distal	-4	no	9.403	8.814	EPSD	ICGC	5.915	Down-regulation
CMGC_MAPK_p38_MAPK14_ST	Q09472	EP300	Q16539	MAPK14	S833	R838C	838	Missense	distal	5	no	12.412	11.542	EPSD	ICGC;COSMIC	5.915	Down-regulation
CMGC_MAPK_p38_MAPK14_ST	Q09472	EP300	Q16539	MAPK14	S833	L827R	827	Missense	distal	-6	no	12.412	13.526	EPSD	ICGC	5.915	Up-regulation
CMGC_MAPK_p38_MAPK14_ST	Q09472	EP300	Q16539	MAPK14	T839	R838C	838	Missense	proximal	-1	no	9.838	10.102	EPSD	ICGC;COSMIC	5.915	Up-regulation
CMGC_MAPK_p38_MAPK14_ST	Q09472	EP300	Q16539	MAPK14	T841	R838C	838	Missense	distal	-3	no	11.347	9.151	EPSD	ICGC;COSMIC	5.915	Down-regulation
CMGC_MAPK_p38_MAPK14_ST	Q09472	EP300	Q16539	MAPK14	T845	R838C	838	Missense	distal	-7	no	7.713	7.321	EPSD	ICGC;COSMIC	5.915	Down-regulation
CMGC_MAPK_p38_MAPK14_ST	Q09472	EP300	Q16539	MAPK14	T885	P881S	881	Missense	distal	-4	no	9.555	9.468	EPSD	ICGC;COSMIC	5.915	Down-regulation
CMGC_MAPK_p38_MAPK14_ST	Q09472	EP300	Q16539	MAPK14	T887	P881S	881	Missense	distal	-6	no	9.099	9.706	EPSD	ICGC;COSMIC	5.915	Up-regulation
CMGC_MAPK_p38_MAPK14_ST	Q09472	EP300	Q16539	MAPK14	T938	P934T	934	Missense	distal	-4	no	7.571	7.761	EPSD	ICGC;COSMIC	5.915	Up-regulation
CMGC_MAPK_p38_MAPK14_ST	Q09472	EP300	Q16539	MAPK14	T938	V945L	945	Missense	distal	7	no	7.571	7.273	EPSD	ICGC	5.915	Down-regulation
CMGC_MAPK_p38_MAPK14_ST	Q09472	EP300	Q16539	MAPK14	T938	A944S	944	Missense	distal	6	no	7.571	7.516	EPSD	ICGC;COSMIC	5.915	Down-regulation
CMGC_MAPK_p38_MAPK14_ST	Q09472	EP300	Q16539	MAPK14	T938	P939S	939	Missense	proximal	1	no	7.571	0.288	EPSD	ICGC	5.915	Loss
CMGC_MAPK_p38_MAPK14_ST	Q09472	EP300	Q16539	MAPK14	S1033	P1039S	1039	Missense	distal	6	no	7.714	7.702	EPSD	ICGC;COSMIC	5.915	Down-regulation
CMGC_MAPK_p38_MAPK14_ST	Q09472	EP300	Q16539	MAPK14	S1033	S1033L	1033	Missense	central	0	yes	7.714	0.000	EPSD	ICGC;COSMIC	5.915	Loss
CMGC_MAPK_p38_MAPK14_ST	Q09472	EP300	Q16539	MAPK14	S1033	Q1036K	1036	Missense	distal	3	no	7.714	7.690	EPSD	ICGC;COSMIC	5.915	Down-regulation
CMGC_MAPK_p38_MAPK14_ST	Q09472	EP300	Q16539	MAPK14	S1038	P1039S	1039	Missense	proximal	1	no	10.963	3.679	EPSD	ICGC;COSMIC	5.915	Loss
CMGC_MAPK_p38_MAPK14_ST	Q09472	EP300	Q16539	MAPK14	S1038	S1033L	1033	Missense	distal	-5	no	10.963	11.692	EPSD	ICGC;COSMIC	5.915	Up-regulation
CMGC_MAPK_p38_MAPK14_ST	Q09472	EP300	Q16539	MAPK14	S1038	Q1036K	1036	Missense	proximal	-2	no	10.963	10.687	EPSD	ICGC;COSMIC	5.915	Down-regulation
CMGC_MAPK_p38_MAPK14_ST	Q09472	EP300	Q16539	MAPK14	S1193	R1187H	1187	Missense	distal	-6	no	6.121	5.158	EPSD	ICGC;COSMIC	5.915	Loss
CMGC_MAPK_p38_MAPK14_ST	Q09472	EP300	Q16539	MAPK14	T1724	D1729N	1729	Missense	distal	5	no	7.140	7.348	EPSD	ICGC;COSMIC	5.915	Up-regulation
CMGC_MAPK_p38_MAPK14_ST	Q09472	EP300	Q16539	MAPK14	S1726	D1729N	1729	Missense	distal	3	no	9.245	9.239	EPSD	ICGC;COSMIC	5.915	Down-regulation
CMGC_MAPK_p38_MAPK14_ST	Q09472	EP300	Q16539	MAPK14	S1849	P1850S	1850	Missense	proximal	1	no	9.238	1.954	EPSD	ICGC;COSMIC	5.915	Loss
CMGC_MAPK_p38_MAPK14_ST	Q09472	EP300	Q16539	MAPK14	T1851	P1850S	1850	Missense	proximal	-1	no	9.693	9.600	EPSD	ICGC;COSMIC	5.915	Down-regulation
CMGC_MAPK_p38_MAPK14_ST	Q09472	EP300	Q16539	MAPK14	T1854	P1850S	1850	Missense	distal	-4	no	11.552	11.464	EPSD	ICGC;COSMIC	5.915	Down-regulation
CMGC_MAPK_p38_MAPK14_ST	Q09472	EP300	Q16539	MAPK14	T1857	P1850S	1850	Missense	distal	-7	no	10.922	11.010	EPSD	ICGC;COSMIC	5.915	Up-regulation
CMGC_MAPK_p38_MAPK14_ST	Q09472	EP300	Q16539	MAPK14	T1906	P1910T	1910	Missense	distal	4	no	9.300	9.478	EPSD	ICGC;COSMIC	5.915	Up-regulation
CMGC_MAPK_p38_MAPK14_ST	Q09472	EP300	Q16539	MAPK14	T1909	P1910T	1910	Missense	proximal	1	no	11.278	3.825	EPSD	ICGC;COSMIC	5.915	Loss
CMGC_MAPK_p38_MAPK14_ST	Q09472	EP300	Q16539	MAPK14	T1913	P1910T	1910	Missense	distal	-3	no	5.597	6.043	EPSD	ICGC;COSMIC	5.915	Gain
CMGC_MAPK_p38_MAPK14_ST	Q09472	EP300	Q16539	MAPK14	T1960	M1959I	1959	Missense	proximal	-1	no	7.424	7.278	EPSD	ICGC	5.915	Down-regulation
CMGC_MAPK_p38_MAPK14_ST	Q09472	EP300	Q16539	MAPK14	S2279	M2278I	2278	Missense	proximal	-1	no	10.469	10.323	EPSD	ICGC;COSMIC	5.915	Down-regulation
CMGC_MAPK_p38_MAPK14_ST	Q09472	EP300	Q16539	MAPK14	S2279	P2286T	2286	Missense	distal	7	no	10.469	10.370	EPSD	ICGC;COSMIC	5.915	Down-regulation
CMGC_MAPK_p38_MAPK14_ST	Q09472	EP300	Q16539	MAPK14	S2279	Q2281H	2281	Missense	proximal	2	no	10.469	10.512	EPSD	ICGC;COSMIC	5.915	Up-regulation
CMGC_MAPK_p38_MAPK14_ST	Q09472	EP300	Q16539	MAPK14	S2309	S2302Y	2302	Missense	distal	-7	no	7.151	6.590	EPSD	ICGC	5.915	Down-regulation
CMGC_MAPK_p38_MAPK14_ST	Q09472	EP300	Q16539	MAPK14	S2366	G2362W	2362	Missense	distal	-4	no	11.588	12.230	EPSD	ICGC;COSMIC	5.915	Up-regulation
CMGC_MAPK_p38_MAPK14_ST	Q09472	EP300	Q16539	MAPK14	S2366	P2367Q	2367	Missense	proximal	1	no	11.588	4.380	EPSD	ICGC;COSMIC	5.915	Loss
CMGC_MAPK_p38_MAPK14_ST	Q09472	EP300	Q16539	MAPK14	S2366	N2370T	2370	Missense	distal	4	no	11.588	11.843	EPSD	ICGC	5.915	Up-regulation
CMGC_MAPK_p38_MAPK14_ST	P15336	ATF2	Q16539	MAPK14	S136	E130K	130	Missense	distal	-6	no	8.563	8.149	EPSD	ICGC;COSMIC	5.915	Down-regulation
CMGC_MAPK_p38_MAPK14_ST	P15336	ATF2	Q16539	MAPK14	T320	S321G	321	Missense	proximal	1	no	7.720	7.209	EPSD	ICGC;COSMIC	5.915	Down-regulation
CMGC_MAPK_p38_MAPK14_ST	P15336	ATF2	Q16539	MAPK14	T325	S321G	321	Missense	distal	-4	no	9.210	9.207	EPSD	ICGC;COSMIC	5.915	Down-regulation
CMGC_MAPK_p38_MAPK14_ST	P15336	ATF2	Q16539	MAPK14	S328	S321G	321	Missense	distal	-7	no	11.961	11.894	EPSD	ICGC;COSMIC	5.915	Down-regulation
CMGC_MAPK_p38_MAPK14_ST	P15336	ATF2	Q16539	MAPK14	T333	S340L	340	Missense	distal	7	no	10.979	10.595	EPSD	ICGC;COSMIC	5.915	Down-regulation
CMGC_MAPK_p38_MAPK14_ST	P15336	ATF2	Q16539	MAPK14	T333	Q337H	337	Missense	distal	4	no	10.979	10.790	EPSD	ICGC;COSMIC	5.915	Down-regulation
CMGC_MAPK_p38_MAPK14_ST	P15336	ATF2	Q16539	MAPK14	T336	S340L	340	Missense	distal	4	no	6.363	5.285	EPSD	ICGC;COSMIC	5.915	Loss
CMGC_MAPK_p38_MAPK14_ST	P15336	ATF2	Q16539	MAPK14	T336	Q337H	337	Missense	proximal	1	no	6.363	-0.082	EPSD	ICGC;COSMIC	5.915	Loss
CMGC_MAPK_p38_MAPK14_ST	Q9NRR4	DROSHA	Q16539	MAPK14	S201	S200N	200	Missense	proximal	-1	no	9.068	9.140	EPSD	ICGC	5.915	Up-regulation
CMGC_MAPK_p38_MAPK14_ST	Q9NRR4	DROSHA	Q16539	MAPK14	S201	P194T	194	Missense	distal	-7	no	9.068	9.086	EPSD	ICGC	5.915	Up-regulation
CMGC_MAPK_p38_MAPK14_ST	Q9NRR4	DROSHA	Q16539	MAPK14	S201	R205G	205	Missense	distal	4	no	9.068	9.553	EPSD	ICGC;COSMIC	5.915	Up-regulation
CMGC_MAPK_p38_MAPK14_ST	Q9NRR4	DROSHA	Q16539	MAPK14	S201	F204L	204	Missense	distal	3	no	9.068	9.034	EPSD	ICGC;COSMIC	5.915	Down-regulation
CMGC_MAPK_p38_MAPK14_ST	Q9NRR4	DROSHA	Q16539	MAPK14	S221	P216T	216	Missense	distal	-5	no	11.714	11.707	EPSD;PhosphoSitePlus	ICGC;COSMIC	5.915	Down-regulation
CMGC_MAPK_p38_MAPK14_ST	Q9NRR4	DROSHA	Q16539	MAPK14	T274	R279S	279	Missense	distal	5	no	11.616	11.926	EPSD;PhosphoSitePlus	ICGC	5.915	Up-regulation
CMGC_MAPK_p38_MAPK14_ST	Q9NRR4	DROSHA	Q16539	MAPK14	T274	R271Q	271	Missense	distal	-3	no	11.616	9.837	EPSD;PhosphoSitePlus	ICGC;COSMIC	5.915	Down-regulation
CMGC_MAPK_p38_MAPK14_ST	Q9NRR4	DROSHA	Q16539	MAPK14	S300	S300L	300	Missense	central	0	yes	12.619	0.000	EPSD;PhosphoSitePlus	ICGC;COSMIC	5.915	Loss
CMGC_MAPK_p38_MAPK14_ST	Q9NRR4	DROSHA	Q16539	MAPK14	S300	N297K	297	Missense	distal	-3	no	12.619	12.591	EPSD;PhosphoSitePlus	ICGC	5.915	Down-regulation
CMGC_MAPK_p38_MAPK14_ST	Q9NRR4	DROSHA	Q16539	MAPK14	T330	G328V	328	Missense	proximal	-2	no	11.414	11.276	EPSD	ICGC;COSMIC	5.915	Down-regulation
CMGC_MAPK_p38_MAPK14_ST	Q9NRR4	DROSHA	Q16539	MAPK14	S355	P356Q	356	Missense	proximal	1	no	9.148	1.939	EPSD;PhosphoSitePlus	ICGC	5.915	Loss
CMGC_MAPK_p38_MAPK14_ST	Q9NRR4	DROSHA	Q16539	MAPK14	S355	H353N	353	Missense	proximal	-2	no	9.148	10.239	EPSD;PhosphoSitePlus	ICGC	5.915	Up-regulation
CMGC_MAPK_p38_MAPK14_ST	Q9NRR4	DROSHA	Q16539	MAPK14	T958	R951C	951	Missense	distal	-7	no	6.717	6.325	EPSD	ICGC;COSMIC	5.915	Down-regulation
CMGC_MAPK_p38_MAPK14_ST	P42224	STAT1	Q16539	MAPK14	T489	P491T	491	Missense	proximal	2	no	8.681	8.822	EPSD	ICGC	5.915	Up-regulation
CMGC_MAPK_p38_MAPK14_ST	P42224	STAT1	Q16539	MAPK14	T489	R482M	482	Missense	distal	-7	no	8.681	8.834	EPSD	ICGC;COSMIC	5.915	Up-regulation
CMGC_MAPK_p38_MAPK14_ST	P42224	STAT1	Q16539	MAPK14	S727	D721E	721	Missense	distal	-6	no	12.060	12.639	PhosphoSitePlus	ICGC	5.915	Up-regulation
CMGC_MAPK_p38_MAPK14_ST	P42224	STAT1	Q16539	MAPK14	S727	E733Q	733	Missense	distal	6	no	12.060	11.992	PhosphoSitePlus	ICGC;COSMIC	5.915	Down-regulation
CMGC_MAPK_p38_MAPK14_ST	P42224	STAT1	Q16539	MAPK14	S727	V734L	734	Missense	distal	7	no	12.060	11.762	PhosphoSitePlus	ICGC;COSMIC	5.915	Down-regulation
CMGC_MAPK_p38_MAPK14_ST	P42224	STAT1	Q16539	MAPK14	S735	R736Q	736	Missense	proximal	1	no	5.500	6.227	EPSD	ICGC;COSMIC	5.915	Gain
CMGC_MAPK_p38_MAPK14_ST	Q99958	FOXC2	Q16539	MAPK14	S36	M38I	38	Missense	proximal	2	no	9.686	9.461	EPSD	ICGC	5.915	Down-regulation
CMGC_MAPK_p38_MAPK14_ST	Q99958	FOXC2	Q16539	MAPK14	S36	P37H	37	Missense	proximal	1	no	9.686	-3.967	EPSD	ICGC;COSMIC	5.915	Loss
CMGC_MAPK_p38_MAPK14_ST	Q99958	FOXC2	Q16539	MAPK14	T197	D202G	202	Missense	distal	5	no	13.330	13.619	EPSD	ICGC;COSMIC	5.915	Up-regulation
CMGC_MAPK_p38_MAPK14_ST	Q99958	FOXC2	Q16539	MAPK14	T197	P204S	204	Missense	distal	7	no	13.330	13.552	EPSD	ICGC	5.915	Up-regulation
CMGC_MAPK_p38_MAPK14_ST	Q99958	FOXC2	Q16539	MAPK14	T197	A201T	201	Missense	distal	4	no	13.330	13.374	EPSD	ICGC	5.915	Up-regulation
CMGC_MAPK_p38_MAPK14_ST	Q99958	FOXC2	Q16539	MAPK14	S219	V212A	212	Missense	distal	-7	no	8.063	8.881	EPSD	ICGC;COSMIC	5.915	Up-regulation
CMGC_MAPK_p38_MAPK14_ST	Q99958	FOXC2	Q16539	MAPK14	S232	E234K	234	Missense	proximal	2	no	10.614	10.299	EPSD	ICGC	5.915	Down-regulation
CMGC_MAPK_p38_MAPK14_ST	Q99958	FOXC2	Q16539	MAPK14	S235	S240I	240	Missense	distal	5	no	6.420	5.327	EPSD	ICGC	5.915	Loss
CMGC_MAPK_p38_MAPK14_ST	Q99958	FOXC2	Q16539	MAPK14	S235	E234K	234	Missense	proximal	-1	no	6.420	6.481	EPSD	ICGC	5.915	Up-regulation
CMGC_MAPK_p38_MAPK14_ST	Q99958	FOXC2	Q16539	MAPK14	S240	S240I	240	Missense	central	0	yes	9.958	0.000	EPSD	ICGC	5.915	Loss
CMGC_MAPK_p38_MAPK14_ST	Q99958	FOXC2	Q16539	MAPK14	S240	E234K	234	Missense	distal	-6	no	9.958	9.544	EPSD	ICGC	5.915	Down-regulation
CMGC_MAPK_p38_MAPK14_ST	Q99958	FOXC2	Q16539	MAPK14	S240	A245P	245	Missense	distal	5	no	9.958	10.146	EPSD	ICGC;COSMIC	5.915	Up-regulation
CMGC_MAPK_p38_MAPK14_ST	Q99958	FOXC2	Q16539	MAPK14	S240	A245T	245	Missense	distal	5	no	9.958	10.430	EPSD	ICGC;COSMIC	5.915	Up-regulation
CMGC_MAPK_p38_MAPK14_ST	Q99958	FOXC2	Q16539	MAPK14	T247	S240I	240	Missense	distal	-7	no	13.450	13.030	EPSD	ICGC	5.915	Down-regulation
CMGC_MAPK_p38_MAPK14_ST	Q99958	FOXC2	Q16539	MAPK14	T247	G250S	250	Missense	distal	3	no	13.450	13.409	EPSD	ICGC;COSMIC	5.915	Down-regulation
CMGC_MAPK_p38_MAPK14_ST	Q99958	FOXC2	Q16539	MAPK14	T247	A245P	245	Missense	proximal	-2	no	13.450	14.113	EPSD	ICGC;COSMIC	5.915	Up-regulation
CMGC_MAPK_p38_MAPK14_ST	Q99958	FOXC2	Q16539	MAPK14	T247	A245T	245	Missense	proximal	-2	no	13.450	13.393	EPSD	ICGC;COSMIC	5.915	Down-regulation
CMGC_MAPK_p38_MAPK14_ST	Q99958	FOXC2	Q16539	MAPK14	T247	G250V	250	Missense	distal	3	no	13.450	13.451	EPSD	ICGC;COSMIC	5.915	Up-regulation
CMGC_MAPK_p38_MAPK14_ST	Q99958	FOXC2	Q16539	MAPK14	S251	G250S	250	Missense	proximal	-1	no	11.391	11.178	EPSD	ICGC;COSMIC	5.915	Down-regulation
CMGC_MAPK_p38_MAPK14_ST	Q99958	FOXC2	Q16539	MAPK14	S251	A245P	245	Missense	distal	-6	no	11.391	11.327	EPSD	ICGC;COSMIC	5.915	Down-regulation
CMGC_MAPK_p38_MAPK14_ST	Q99958	FOXC2	Q16539	MAPK14	S251	A245T	245	Missense	distal	-6	no	11.391	11.661	EPSD	ICGC;COSMIC	5.915	Up-regulation
CMGC_MAPK_p38_MAPK14_ST	Q99958	FOXC2	Q16539	MAPK14	S251	G250V	250	Missense	proximal	-1	no	11.391	11.394	EPSD	ICGC;COSMIC	5.915	Up-regulation
CMGC_MAPK_p38_MAPK14_ST	Q99958	FOXC2	Q16539	MAPK14	S281	I275N	275	Missense	distal	-6	no	9.993	10.865	EPSD	ICGC	5.915	Up-regulation
CMGC_MAPK_p38_MAPK14_ST	Q99958	FOXC2	Q16539	MAPK14	S288	G290R	290	Missense	proximal	2	no	14.673	14.756	EPSD	ICGC;COSMIC	5.915	Up-regulation
CMGC_MAPK_p38_MAPK14_ST	Q99958	FOXC2	Q16539	MAPK14	T484	R489H	489	Missense	distal	5	no	10.131	9.436	EPSD	ICGC;COSMIC	5.915	Down-regulation
CMGC_MAPK_p38_MAPK14_ST	P36956	SREBF1	Q16539	MAPK14	S63	S63F	63	Missense	central	0	yes	9.913	0.000	EPSD;PhosphoSitePlus	ICGC;COSMIC	5.915	Loss
CMGC_MAPK_p38_MAPK14_ST	P36956	SREBF1	Q16539	MAPK14	S63	G58D	58	Missense	distal	-5	no	9.913	10.155	EPSD;PhosphoSitePlus	ICGC;COSMIC	5.915	Up-regulation
CMGC_MAPK_p38_MAPK14_ST	P36956	SREBF1	Q16539	MAPK14	S63	G57R	57	Missense	distal	-6	no	9.913	10.288	EPSD;PhosphoSitePlus	ICGC;COSMIC	5.915	Up-regulation
CMGC_MAPK_p38_MAPK14_ST	P36956	SREBF1	Q16539	MAPK14	S63	A62D	62	Missense	proximal	-1	no	9.913	10.110	EPSD;PhosphoSitePlus	ICGC	5.915	Up-regulation
CMGC_MAPK_p38_MAPK14_ST	P36956	SREBF1	Q16539	MAPK14	S63	S68P	68	Missense	distal	5	no	9.913	9.462	EPSD;PhosphoSitePlus	ICGC;COSMIC	5.915	Down-regulation
CMGC_MAPK_p38_MAPK14_ST	P36956	SREBF1	Q16539	MAPK14	T105	P111T	111	Missense	distal	6	no	9.499	9.525	EPSD	ICGC;COSMIC	5.915	Up-regulation
CMGC_MAPK_p38_MAPK14_ST	P36956	SREBF1	Q16539	MAPK14	T105	P99H	99	Missense	distal	-6	no	9.499	9.037	EPSD	ICGC;COSMIC	5.915	Down-regulation
CMGC_MAPK_p38_MAPK14_ST	P36956	SREBF1	Q16539	MAPK14	T105	P111R	111	Missense	distal	6	no	9.499	9.487	EPSD	ICGC	5.915	Down-regulation
CMGC_MAPK_p38_MAPK14_ST	P36956	SREBF1	Q16539	MAPK14	T105	S112F	112	Missense	distal	7	no	9.499	8.629	EPSD	ICGC	5.915	Down-regulation
CMGC_MAPK_p38_MAPK14_ST	P36956	SREBF1	Q16539	MAPK14	S117	P111T	111	Missense	distal	-6	no	9.578	9.912	EPSD	ICGC;COSMIC	5.915	Up-regulation
CMGC_MAPK_p38_MAPK14_ST	P36956	SREBF1	Q16539	MAPK14	S117	P111R	111	Missense	distal	-6	no	9.578	10.078	EPSD	ICGC	5.915	Up-regulation
CMGC_MAPK_p38_MAPK14_ST	P36956	SREBF1	Q16539	MAPK14	S117	S112F	112	Missense	distal	-5	no	9.578	10.363	EPSD	ICGC	5.915	Up-regulation
CMGC_MAPK_p38_MAPK14_ST	P36956	SREBF1	Q16539	MAPK14	S117	P114H	114	Missense	distal	-3	no	9.578	9.100	EPSD	ICGC	5.915	Down-regulation
CMGC_MAPK_p38_MAPK14_ST	P36956	SREBF1	Q16539	MAPK14	S117	P118H	118	Missense	proximal	1	no	9.578	-4.076	EPSD	ICGC;COSMIC	5.915	Loss
CMGC_MAPK_p38_MAPK14_ST	P36956	SREBF1	Q16539	MAPK14	S117	A115T	115	Missense	proximal	-2	no	9.578	9.520	EPSD	ICGC;COSMIC	5.915	Down-regulation
CMGC_MAPK_p38_MAPK14_ST	P36956	SREBF1	Q16539	MAPK14	S117	P120L	120	Missense	distal	3	no	9.578	9.611	EPSD	ICGC;COSMIC	5.915	Up-regulation
CMGC_MAPK_p38_MAPK14_ST	P36956	SREBF1	Q16539	MAPK14	S117	S117F	117	Missense	central	0	yes	9.578	0.000	EPSD	ICGC;COSMIC	5.915	Loss
CMGC_MAPK_p38_MAPK14_ST	P38936	CDKN1A	Q16539	MAPK14	T57	D52N	52	Missense	distal	-5	no	8.710	8.550	EPSD;PhosphoSitePlus	ICGC;COSMIC	5.915	Down-regulation
CMGC_MAPK_p38_MAPK14_ST	P38936	CDKN1A	Q16539	MAPK14	T57	E56D	56	Missense	proximal	-1	no	8.710	9.054	EPSD;PhosphoSitePlus	ICGC	5.915	Up-regulation
CMGC_MAPK_p38_MAPK14_ST	P38936	CDKN1A	Q16539	MAPK14	T57	F51V	51	Missense	distal	-6	no	8.710	9.443	EPSD;PhosphoSitePlus	ICGC;COSMIC	5.915	Up-regulation
CMGC_MAPK_p38_MAPK14_ST	P38936	CDKN1A	Q16539	MAPK14	S130	P131T	131	Missense	proximal	1	no	13.304	5.851	PhosphoSitePlus;EPSD	ICGC;COSMIC	5.915	Loss
CMGC_MAPK_p38_MAPK14_ST	P38936	CDKN1A	Q16539	MAPK14	S130	P131Q	131	Missense	proximal	1	no	13.304	6.096	PhosphoSitePlus;EPSD	ICGC;COSMIC	5.915	Down-regulation
CMGC_MAPK_p38_MAPK14_ST	P38936	CDKN1A	Q16539	MAPK14	S130	G129W	129	Missense	proximal	-1	no	13.304	13.272	PhosphoSitePlus;EPSD	ICGC;COSMIC	5.915	Down-regulation
CMGC_MAPK_p38_MAPK14_ST	P38936	CDKN1A	Q16539	MAPK14	S146	R142Q	142	Missense	distal	-4	no	5.717	6.085	EPSD	ICGC	5.915	Gain
CMGC_MAPK_p38_MAPK14_ST	Q15750	TAB1	Q16539	MAPK14	S339	R333Q	333	Missense	distal	-6	no	6.260	5.590	EPSD	ICGC	5.915	Loss
CMGC_MAPK_p38_MAPK14_ST	Q15750	TAB1	Q16539	MAPK14	S339	A343S	343	Missense	distal	4	no	6.260	6.565	EPSD	ICGC	5.915	Up-regulation
CMGC_MAPK_p38_MAPK14_ST	Q15750	TAB1	Q16539	MAPK14	S339	S339I	339	Missense	central	0	yes	6.260	0.000	EPSD	ICGC;COSMIC	5.915	Loss
CMGC_MAPK_p38_MAPK14_ST	Q15750	TAB1	Q16539	MAPK14	T376	S373I	373	Missense	distal	-3	no	11.469	9.397	EPSD	ICGC	5.915	Down-regulation
CMGC_MAPK_p38_MAPK14_ST	Q15750	TAB1	Q16539	MAPK14	T376	P381S	381	Missense	distal	5	no	11.469	11.920	EPSD	ICGC	5.915	Up-regulation
CMGC_MAPK_p38_MAPK14_ST	Q15750	TAB1	Q16539	MAPK14	T376	S378I	378	Missense	proximal	2	no	11.469	10.990	EPSD	ICGC	5.915	Down-regulation
CMGC_MAPK_p38_MAPK14_ST	Q15750	TAB1	Q16539	MAPK14	T376	Q374H	374	Missense	proximal	-2	no	11.469	10.218	EPSD	ICGC;COSMIC	5.915	Down-regulation
CMGC_MAPK_p38_MAPK14_ST	Q15750	TAB1	Q16539	MAPK14	T376	S378R	378	Missense	proximal	2	no	11.469	11.324	EPSD	ICGC;COSMIC	5.915	Down-regulation
CMGC_MAPK_p38_MAPK14_ST	Q15750	TAB1	Q16539	MAPK14	T376	Q374K	374	Missense	proximal	-2	no	11.469	11.193	EPSD	ICGC;COSMIC	5.915	Down-regulation
CMGC_MAPK_p38_MAPK14_ST	Q15750	TAB1	Q16539	MAPK14	S378	S373I	373	Missense	distal	-5	no	10.594	10.993	EPSD	ICGC	5.915	Up-regulation
CMGC_MAPK_p38_MAPK14_ST	Q15750	TAB1	Q16539	MAPK14	S378	P381S	381	Missense	distal	3	no	10.594	10.554	EPSD	ICGC	5.915	Down-regulation
CMGC_MAPK_p38_MAPK14_ST	Q15750	TAB1	Q16539	MAPK14	S378	S378I	378	Missense	central	0	yes	10.594	0.000	EPSD	ICGC	5.915	Loss
CMGC_MAPK_p38_MAPK14_ST	Q15750	TAB1	Q16539	MAPK14	S378	Q374H	374	Missense	distal	-4	no	10.594	10.436	EPSD	ICGC;COSMIC	5.915	Down-regulation
CMGC_MAPK_p38_MAPK14_ST	Q15750	TAB1	Q16539	MAPK14	S378	S378R	378	Missense	central	0	yes	10.594	0.000	EPSD	ICGC;COSMIC	5.915	Loss
CMGC_MAPK_p38_MAPK14_ST	Q15750	TAB1	Q16539	MAPK14	S378	Q374K	374	Missense	distal	-4	no	10.594	10.141	EPSD	ICGC;COSMIC	5.915	Down-regulation
CMGC_MAPK_p38_MAPK14_ST	Q15750	TAB1	Q16539	MAPK14	T431	L434I	434	Missense	distal	3	no	10.605	10.627	EPSD;PhosphoSitePlus	ICGC;COSMIC	5.915	Up-regulation
CMGC_MAPK_p38_MAPK14_ST	Q15750	TAB1	Q16539	MAPK14	T431	S438R	438	Missense	distal	7	no	10.605	10.639	EPSD;PhosphoSitePlus	ICGC;COSMIC	5.915	Up-regulation
CMGC_MAPK_p38_MAPK14_ST	Q15750	TAB1	Q16539	MAPK14	S438	L434I	434	Missense	distal	-4	no	11.609	11.176	EPSD;PhosphoSitePlus	ICGC;COSMIC	5.915	Down-regulation
CMGC_MAPK_p38_MAPK14_ST	Q15750	TAB1	Q16539	MAPK14	S438	S438R	438	Missense	central	0	yes	11.609	0.000	EPSD;PhosphoSitePlus	ICGC;COSMIC	5.915	Loss
CMGC_MAPK_p38_MAPK14_ST	Q15750	TAB1	Q16539	MAPK14	S453	G459R	459	Missense	distal	6	no	6.000	5.878	EPSD;PhosphoSitePlus	ICGC;CCLE	5.915	Loss
CMGC_MAPK_p38_MAPK14_ST	Q8WYK2	JDP2	Q16539	MAPK14	T143	V141I	141	Missense	proximal	-2	no	6.578	6.837	EPSD	ICGC;COSMIC	5.915	Up-regulation
CMGC_MAPK_p38_MAPK14_ST	Q8WYK2	JDP2	Q16539	MAPK14	T143	K147M	147	Missense	distal	4	no	6.578	6.221	EPSD	ICGC;COSMIC	5.915	Down-regulation
CMGC_MAPK_p38_MAPK14_ST	Q8WYK2	JDP2	Q16539	MAPK14	T148	V141I	141	Missense	distal	-7	no	10.947	11.231	PhosphoSitePlus	ICGC;COSMIC	5.915	Up-regulation
CMGC_MAPK_p38_MAPK14_ST	Q8WYK2	JDP2	Q16539	MAPK14	T148	K147M	147	Missense	proximal	-1	no	10.947	11.097	PhosphoSitePlus	ICGC;COSMIC	5.915	Up-regulation
CMGC_MAPK_p38_MAPK14_ST	Q8WYK2	JDP2	Q16539	MAPK14	S151	K147M	147	Missense	distal	-4	no	6.420	6.565	EPSD	ICGC;COSMIC	5.915	Up-regulation
CMGC_MAPK_p38_MAPK14_ST	P78356	PIP4K2B	Q16539	MAPK14	S2	S3P	3	Missense	proximal	1	no	2.642	9.926	EPSD	ICGC	5.915	Gain
CMGC_MAPK_p38_MAPK14_ST	P78356	PIP4K2B	Q16539	MAPK14	T9	S3P	3	Missense	distal	-6	no	6.080	5.473	EPSD	ICGC	5.915	Loss
CMGC_MAPK_p38_MAPK14_ST	P78356	PIP4K2B	Q16539	MAPK14	T322	L317P	317	Missense	distal	-5	no	10.505	10.223	EPSD	ICGC	5.915	Down-regulation
CMGC_MAPK_p38_MAPK14_ST	P78356	PIP4K2B	Q16539	MAPK14	T322	C318R	318	Missense	distal	-4	no	10.505	10.054	EPSD	ICGC	5.915	Down-regulation
CMGC_MAPK_p38_MAPK14_ST	P78356	PIP4K2B	Q16539	MAPK14	T322	L316P	316	Missense	distal	-6	no	10.505	11.118	EPSD	ICGC	5.915	Up-regulation
CMGC_MAPK_p38_MAPK14_ST	P78356	PIP4K2B	Q16539	MAPK14	T322	N315H	315	Missense	distal	-7	no	10.505	10.252	EPSD	ICGC	5.915	Down-regulation
CMGC_MAPK_p38_MAPK14_ST	P78536	ADAM17	Q16539	MAPK14	S266	A270T	270	Missense	distal	4	no	7.242	7.287	EPSD	ICGC;COSMIC	5.915	Up-regulation
CMGC_MAPK_p38_MAPK14_ST	P78536	ADAM17	Q16539	MAPK14	S266	R263W	263	Missense	distal	-3	no	7.242	4.885	EPSD	ICGC;COSMIC	5.915	Loss
CMGC_MAPK_p38_MAPK14_ST	Q14721	KCNB1	Q16539	MAPK14	S503	G510R	510	Missense	distal	7	no	7.680	7.858	EPSD	ICGC;COSMIC	5.915	Up-regulation
CMGC_MAPK_p38_MAPK14_ST	Q14721	KCNB1	Q16539	MAPK14	S607	S611L	611	Missense	distal	4	no	7.581	6.503	EPSD	ICGC;COSMIC	5.915	Down-regulation
CMGC_MAPK_p38_MAPK14_ST	Q14721	KCNB1	Q16539	MAPK14	S607	S605P	605	Missense	proximal	-2	no	7.581	8.070	EPSD	ICGC	5.915	Up-regulation
CMGC_MAPK_p38_MAPK14_ST	Q14721	KCNB1	Q16539	MAPK14	S607	R603T	603	Missense	distal	-4	no	7.581	7.848	EPSD	ICGC	5.915	Up-regulation
CMGC_MAPK_p38_MAPK14_ST	Q14721	KCNB1	Q16539	MAPK14	S720	L714W	714	Missense	distal	-6	no	11.321	11.117	EPSD	ICGC;COSMIC	5.915	Down-regulation
CMGC_MAPK_p38_MAPK14_ST	Q14721	KCNB1	Q16539	MAPK14	S730	R736W	736	Missense	distal	6	no	6.555	6.291	EPSD	ICGC	5.915	Down-regulation
CMGC_MAPK_p38_MAPK14_ST	Q14721	KCNB1	Q16539	MAPK14	T733	R736W	736	Missense	distal	3	no	10.847	10.931	EPSD	ICGC	5.915	Up-regulation
CMGC_MAPK_p38_MAPK14_ST	Q14721	KCNB1	Q16539	MAPK14	S737	R736W	736	Missense	proximal	-1	no	11.876	12.164	EPSD	ICGC	5.915	Up-regulation
CMGC_MAPK_p38_MAPK14_ST	Q14721	KCNB1	Q16539	MAPK14	S737	I744M	744	Missense	distal	7	no	11.876	12.478	EPSD	ICGC;COSMIC	5.915	Up-regulation
CMGC_MAPK_p38_MAPK14_ST	Q14721	KCNB1	Q16539	MAPK14	S783	P784T	784	Missense	proximal	1	no	12.078	4.624	EPSD	ICGC	5.915	Loss
CMGC_MAPK_p38_MAPK14_ST	Q14721	KCNB1	Q16539	MAPK14	S800	P801H	801	Missense	proximal	1	no	11.299	-2.355	PhosphoSitePlus;EPSD	ICGC	5.915	Loss
CMGC_MAPK_p38_MAPK14_ST	Q14721	KCNB1	Q16539	MAPK14	S800	N795K	795	Missense	distal	-5	no	11.299	10.918	PhosphoSitePlus;EPSD	ICGC;COSMIC	5.915	Down-regulation
CMGC_MAPK_p38_MAPK14_ST	Q14721	KCNB1	Q16539	MAPK14	S805	P801H	801	Missense	distal	-4	no	12.550	12.684	EPSD;PhosphoSitePlus	ICGC	5.915	Up-regulation
CMGC_MAPK_p38_MAPK14_ST	Q14721	KCNB1	Q16539	MAPK14	S805	Q811L	811	Missense	distal	6	no	12.550	12.411	EPSD;PhosphoSitePlus	ICGC;COSMIC	5.915	Down-regulation
CMGC_MAPK_p38_MAPK14_ST	Q14721	KCNB1	Q16539	MAPK14	S805	Q811E	811	Missense	distal	6	no	12.550	12.619	EPSD;PhosphoSitePlus	ICGC;COSMIC	5.915	Up-regulation
CMGC_MAPK_p38_MAPK14_ST	P28324	ELK4	Q16539	MAPK14	S180	K178T	178	Missense	proximal	-2	no	10.005	10.577	EPSD	ICGC;COSMIC	5.915	Up-regulation
CMGC_MAPK_p38_MAPK14_ST	P28324	ELK4	Q16539	MAPK14	S180	K179T	179	Missense	proximal	-1	no	10.005	10.148	EPSD	ICGC	5.915	Up-regulation
CMGC_MAPK_p38_MAPK14_ST	P28324	ELK4	Q16539	MAPK14	T185	K178T	178	Missense	distal	-7	no	9.966	9.800	EPSD	ICGC;COSMIC	5.915	Down-regulation
CMGC_MAPK_p38_MAPK14_ST	P28324	ELK4	Q16539	MAPK14	T185	K179T	179	Missense	distal	-6	no	9.966	10.279	EPSD	ICGC	5.915	Up-regulation
CMGC_MAPK_p38_MAPK14_ST	P28324	ELK4	Q16539	MAPK14	T194	P199S	199	Missense	distal	5	no	8.460	8.911	EPSD	ICGC;COSMIC	5.915	Up-regulation
CMGC_MAPK_p38_MAPK14_ST	P28324	ELK4	Q16539	MAPK14	S215	S209L	209	Missense	distal	-6	no	12.470	11.250	EPSD	ICGC	5.915	Down-regulation
CMGC_MAPK_p38_MAPK14_ST	P28324	ELK4	Q16539	MAPK14	S230	P231Q	231	Missense	proximal	1	no	10.160	2.952	EPSD	ICGC;COSMIC	5.915	Loss
CMGC_MAPK_p38_MAPK14_ST	P28324	ELK4	Q16539	MAPK14	S230	T227A	227	Missense	distal	-3	no	10.160	10.065	EPSD	ICGC;COSMIC	5.915	Down-regulation
CMGC_MAPK_p38_MAPK14_ST	P28324	ELK4	Q16539	MAPK14	S381	P388T	388	Missense	distal	7	no	8.221	8.122	EPSD;PhosphoSitePlus	ICGC	5.915	Down-regulation
CMGC_MAPK_p38_MAPK14_ST	P28324	ELK4	Q16539	MAPK14	S381	P388Q	388	Missense	distal	7	no	8.221	8.283	EPSD;PhosphoSitePlus	ICGC	5.915	Up-regulation
CMGC_MAPK_p38_MAPK14_ST	P28324	ELK4	Q16539	MAPK14	S381	W377L	377	Missense	distal	-4	no	8.221	8.181	EPSD;PhosphoSitePlus	ICGC;COSMIC	5.915	Down-regulation
CMGC_MAPK_p38_MAPK14_ST	P28324	ELK4	Q16539	MAPK14	S381	A384S	384	Missense	distal	3	no	8.221	8.206	EPSD;PhosphoSitePlus	ICGC;COSMIC	5.915	Down-regulation
CMGC_MAPK_p38_MAPK14_ST	P28324	ELK4	Q16539	MAPK14	S387	P388T	388	Missense	proximal	1	no	12.952	5.499	PhosphoSitePlus;EPSD	ICGC	5.915	Loss
CMGC_MAPK_p38_MAPK14_ST	P28324	ELK4	Q16539	MAPK14	S387	P388Q	388	Missense	proximal	1	no	12.952	5.744	PhosphoSitePlus;EPSD	ICGC	5.915	Loss
CMGC_MAPK_p38_MAPK14_ST	P28324	ELK4	Q16539	MAPK14	S387	G393C	393	Missense	distal	6	no	12.952	12.556	PhosphoSitePlus;EPSD	ICGC;COSMIC	5.915	Down-regulation
CMGC_MAPK_p38_MAPK14_ST	P28324	ELK4	Q16539	MAPK14	S387	A384S	384	Missense	distal	-3	no	12.952	13.365	PhosphoSitePlus;EPSD	ICGC;COSMIC	5.915	Up-regulation
CMGC_MAPK_p38_MAPK14_ST	P28324	ELK4	Q16539	MAPK14	T420	P418S	418	Missense	proximal	-2	no	13.640	13.151	EPSD	ICGC	5.915	Down-regulation
CMGC_MAPK_p38_MAPK14_ST	P28324	ELK4	Q16539	MAPK14	T420	G417R	417	Missense	distal	-3	no	13.640	15.090	EPSD	ICGC	5.915	Up-regulation
CMGC_MAPK_p38_MAPK14_ST	P28324	ELK4	Q16539	MAPK14	T420	G422C	422	Missense	proximal	2	no	13.640	13.456	EPSD	ICGC;COSMIC	5.915	Down-regulation
CMGC_MAPK_p38_MAPK14_ST	P28324	ELK4	Q16539	MAPK14	T420	P421T	421	Missense	proximal	1	no	13.640	6.187	EPSD	ICGC;COSMIC	5.915	Down-regulation
CMGC_MAPK_p38_MAPK14_ST	P28324	ELK4	Q16539	MAPK14	T420	P423L	423	Missense	distal	3	no	13.640	13.674	EPSD	ICGC;COSMIC	5.915	Up-regulation
CMGC_MAPK_p38_MAPK14_ST	P28324	ELK4	Q16539	MAPK14	T420	P423Q	423	Missense	distal	3	no	13.640	13.668	EPSD	ICGC;COSMIC	5.915	Up-regulation
CMGC_MAPK_p38_MAPK14_ST	P28324	ELK4	Q16539	MAPK14	T420	T420A	420	Missense	central	0	yes	13.640	0.000	EPSD	ICGC	5.915	Loss
CMGC_MAPK_p38_MAPK14_ST	P28324	ELK4	Q16539	MAPK14	S425	P418S	418	Missense	distal	-7	no	14.401	14.488	EPSD	ICGC	5.915	Up-regulation
CMGC_MAPK_p38_MAPK14_ST	P28324	ELK4	Q16539	MAPK14	S425	G422C	422	Missense	distal	-3	no	14.401	13.656	EPSD	ICGC;COSMIC	5.915	Down-regulation
CMGC_MAPK_p38_MAPK14_ST	P28324	ELK4	Q16539	MAPK14	S425	P421T	421	Missense	distal	-4	no	14.401	14.591	EPSD	ICGC;COSMIC	5.915	Up-regulation
CMGC_MAPK_p38_MAPK14_ST	P28324	ELK4	Q16539	MAPK14	S425	P423L	423	Missense	proximal	-2	no	14.401	13.021	EPSD	ICGC;COSMIC	5.915	Down-regulation
CMGC_MAPK_p38_MAPK14_ST	P28324	ELK4	Q16539	MAPK14	S425	P423Q	423	Missense	proximal	-2	no	14.401	13.386	EPSD	ICGC;COSMIC	5.915	Down-regulation
CMGC_MAPK_p38_MAPK14_ST	P28324	ELK4	Q16539	MAPK14	S425	T420A	420	Missense	distal	-5	no	14.401	14.072	EPSD	ICGC	5.915	Down-regulation
CMGC_MAPK_p38_MAPK14_ST	P04792	HSPB1	Q16539	MAPK14	S65	A67T	67	Missense	proximal	2	no	11.176	11.204	EPSD	ICGC;COSMIC	5.915	Up-regulation
CMGC_MAPK_p38_MAPK14_ST	P04792	HSPB1	Q16539	MAPK14	S158	T164A	164	Missense	distal	6	no	14.484	14.501	EPSD	ICGC;COSMIC	5.915	Up-regulation
CMGC_MAPK_p38_MAPK14_ST	P04792	HSPB1	Q16539	MAPK14	S158	P159H	159	Missense	proximal	1	no	14.484	0.830	EPSD	ICGC;COSMIC;CCLE	5.915	Loss
CMGC_MAPK_p38_MAPK14_ST	P04792	HSPB1	Q16539	MAPK14	S199	D200Y	200	Missense	proximal	1	no	7.301	7.456	EPSD	ICGC;COSMIC	5.915	Up-regulation
CMGC_MAPK_p38_MAPK14_ST	P03372	ESR1	Q16539	MAPK14	S104	P99S	99	Missense	distal	-5	no	7.848	7.400	EPSD	ICGC	5.915	Down-regulation
CMGC_MAPK_p38_MAPK14_ST	P03372	ESR1	Q16539	MAPK14	S104	S102N	102	Missense	proximal	-2	no	7.848	7.162	EPSD	ICGC;COSMIC	5.915	Down-regulation
CMGC_MAPK_p38_MAPK14_ST	P03372	ESR1	Q16539	MAPK14	S104	N101S	101	Missense	distal	-3	no	7.848	8.996	EPSD	ICGC;COSMIC	5.915	Up-regulation
CMGC_MAPK_p38_MAPK14_ST	P03372	ESR1	Q16539	MAPK14	S118	H112P	112	Missense	distal	-6	no	10.058	10.521	PhosphoSitePlus;EPSD	ICGC;COSMIC	5.915	Up-regulation
CMGC_MAPK_p38_MAPK14_ST	P03372	ESR1	Q16539	MAPK14	S118	P114L	114	Missense	distal	-4	no	10.058	10.571	PhosphoSitePlus;EPSD	ICGC;COSMIC	5.915	Up-regulation
CMGC_MAPK_p38_MAPK14_ST	P03372	ESR1	Q16539	MAPK14	S294	R300L	300	Missense	distal	6	no	9.793	9.667	EPSD;PhosphoSitePlus	ICGC;COSMIC	5.915	Down-regulation
CMGC_MAPK_p38_MAPK14_ST	P03372	ESR1	Q16539	MAPK14	S294	R300S	300	Missense	distal	6	no	9.793	9.794	EPSD;PhosphoSitePlus	ICGC;COSMIC	5.915	Up-regulation
CMGC_MAPK_p38_MAPK14_ST	P03372	ESR1	Q16539	MAPK14	S294	R300H	300	Missense	distal	6	no	9.793	9.686	EPSD;PhosphoSitePlus	ICGC;COSMIC	5.915	Down-regulation
CMGC_MAPK_p38_MAPK14_ST	P03372	ESR1	Q16539	MAPK14	S341	S341L	341	Missense	central	0	yes	6.264	0.000	EPSD	ICGC;COSMIC;GDSC;CCLE	5.915	Loss
CMGC_MAPK_p38_MAPK14_ST	P03372	ESR1	Q16539	MAPK14	S341	P336A	336	Missense	distal	-5	no	6.264	5.928	EPSD	ICGC;COSMIC	5.915	Down-regulation
CMGC_MAPK_p38_MAPK14_ST	P03372	ESR1	Q16539	MAPK14	S554	R555L	555	Missense	proximal	1	no	6.644	6.528	EPSD	ICGC	5.915	Down-regulation
CMGC_MAPK_p38_MAPK14_ST	Q9H3D4	TP63	Q16539	MAPK14	S30	E33Q	33	Missense	distal	3	no	6.858	6.930	EPSD	ICGC;COSMIC;GDSC;CCLE	5.915	Up-regulation
CMGC_MAPK_p38_MAPK14_ST	Q9H3D4	TP63	Q16539	MAPK14	S30	T25I	25	Missense	distal	-5	no	6.858	6.817	EPSD	ICGC;COSMIC	5.915	Down-regulation
CMGC_MAPK_p38_MAPK14_ST	Q9H3D4	TP63	Q16539	MAPK14	S30	R37L	37	Missense	distal	7	no	6.858	6.439	EPSD	ICGC;COSMIC	5.915	Down-regulation
CMGC_MAPK_p38_MAPK14_ST	Q9H3D4	TP63	Q16539	MAPK14	S30	W31L	31	Missense	proximal	1	no	6.858	4.777	EPSD	ICGC	5.915	Loss
CMGC_MAPK_p38_MAPK14_ST	Q9H3D4	TP63	Q16539	MAPK14	S30	E24D	24	Missense	distal	-6	no	6.858	6.280	EPSD	ICGC	5.915	Down-regulation
CMGC_MAPK_p38_MAPK14_ST	Q9H3D4	TP63	Q16539	MAPK14	S160	S154F	154	Missense	distal	-6	no	12.600	10.835	EPSD	ICGC;COSMIC;GDSC;CCLE	5.915	Down-regulation
CMGC_MAPK_p38_MAPK14_ST	Q9H3D4	TP63	Q16539	MAPK14	S160	P166S	166	Missense	distal	6	no	12.600	12.588	EPSD	ICGC;COSMIC	5.915	Down-regulation
CMGC_MAPK_p38_MAPK14_ST	Q9H3D4	TP63	Q16539	MAPK14	S160	P161A	161	Missense	proximal	1	no	12.600	6.281	EPSD	ICGC	5.915	Down-regulation
CMGC_MAPK_p38_MAPK14_ST	Q9H3D4	TP63	Q16539	MAPK14	S160	P161Q	161	Missense	proximal	1	no	12.600	5.391	EPSD	ICGC;COSMIC	5.915	Loss
CMGC_MAPK_p38_MAPK14_ST	Q9H3D4	TP63	Q16539	MAPK14	S160	S162L	162	Missense	proximal	2	no	12.600	12.111	EPSD	ICGC;COSMIC;GDSC;CCLE	5.915	Down-regulation
CMGC_MAPK_p38_MAPK14_ST	Q9H3D4	TP63	Q16539	MAPK14	S160	I165T	165	Missense	distal	5	no	12.600	13.526	EPSD	ICGC;COSMIC	5.915	Up-regulation
CMGC_MAPK_p38_MAPK14_ST	Q9H3D4	TP63	Q16539	MAPK14	S160	D157N	157	Missense	distal	-3	no	12.600	12.441	EPSD	ICGC;COSMIC	5.915	Down-regulation
CMGC_MAPK_p38_MAPK14_ST	Q9H3D4	TP63	Q16539	MAPK14	S162	P166S	166	Missense	distal	4	no	9.524	9.964	EPSD	ICGC;COSMIC	5.915	Up-regulation
CMGC_MAPK_p38_MAPK14_ST	Q9H3D4	TP63	Q16539	MAPK14	S162	P161A	161	Missense	proximal	-1	no	9.524	9.492	EPSD	ICGC	5.915	Down-regulation
CMGC_MAPK_p38_MAPK14_ST	Q9H3D4	TP63	Q16539	MAPK14	S162	P161Q	161	Missense	proximal	-1	no	9.524	9.413	EPSD	ICGC;COSMIC	5.915	Down-regulation
CMGC_MAPK_p38_MAPK14_ST	Q9H3D4	TP63	Q16539	MAPK14	S162	S162L	162	Missense	central	0	yes	9.524	0.000	EPSD	ICGC;COSMIC;GDSC;CCLE	5.915	Loss
CMGC_MAPK_p38_MAPK14_ST	Q9H3D4	TP63	Q16539	MAPK14	S162	I165T	165	Missense	distal	3	no	9.524	9.442	EPSD	ICGC;COSMIC	5.915	Down-regulation
CMGC_MAPK_p38_MAPK14_ST	Q9H3D4	TP63	Q16539	MAPK14	S162	D157N	157	Missense	distal	-5	no	9.524	9.365	EPSD	ICGC;COSMIC	5.915	Down-regulation
CMGC_MAPK_p38_MAPK14_ST	Q9H3D4	TP63	Q16539	MAPK14	S395	R393C	393	Missense	proximal	-2	no	13.209	12.274	EPSD	ICGC;COSMIC	5.915	Down-regulation
CMGC_MAPK_p38_MAPK14_ST	Q9H3D4	TP63	Q16539	MAPK14	S395	R393S	393	Missense	proximal	-2	no	13.209	13.409	EPSD	ICGC	5.915	Up-regulation
CMGC_MAPK_p38_MAPK14_ST	Q9H3D4	TP63	Q16539	MAPK14	S395	R393H	393	Missense	proximal	-2	no	13.209	11.631	EPSD	ICGC;COSMIC	5.915	Down-regulation
CMGC_MAPK_p38_MAPK14_ST	Q9H3D4	TP63	Q16539	MAPK14	S395	T388P	388	Missense	distal	-7	no	13.209	13.192	EPSD	ICGC;COSMIC	5.915	Down-regulation
CMGC_MAPK_p38_MAPK14_ST	P29353	SHC1	Q16539	MAPK14	S36	L42P	42	Missense	distal	6	no	11.449	11.588	EPSD	ICGC	5.915	Up-regulation
CMGC_MAPK_p38_MAPK14_ST	P29353	SHC1	Q16539	MAPK14	S36	P37T	37	Missense	proximal	1	no	11.449	3.996	EPSD	ICGC;COSMIC	5.915	Loss
CMGC_MAPK_p38_MAPK14_ST	P29353	SHC1	Q16539	MAPK14	S36	S38Y	38	Missense	proximal	2	no	11.449	11.124	EPSD	ICGC	5.915	Down-regulation
CMGC_MAPK_p38_MAPK14_ST	P29353	SHC1	Q16539	MAPK14	S54	G51R	51	Missense	distal	-3	no	9.645	11.095	PhosphoSitePlus;EPSD	ICGC;COSMIC	5.915	Up-regulation
CMGC_MAPK_p38_MAPK14_ST	P29353	SHC1	Q16539	MAPK14	S54	G51V	51	Missense	distal	-3	no	9.645	8.670	PhosphoSitePlus;EPSD	ICGC;COSMIC	5.915	Down-regulation
CMGC_MAPK_p38_MAPK14_ST	P29353	SHC1	Q16539	MAPK14	S80	R77H	77	Missense	distal	-3	no	6.165	4.411	EPSD	ICGC	5.915	Loss
CMGC_MAPK_p38_MAPK14_ST	P29353	SHC1	Q16539	MAPK14	S80	R77C	77	Missense	distal	-3	no	6.165	3.969	EPSD	ICGC;COSMIC;GDSC;CCLE	5.915	Loss
CMGC_MAPK_p38_MAPK14_ST	P29353	SHC1	Q16539	MAPK14	S80	A87V	87	Missense	distal	7	no	6.165	6.056	EPSD	ICGC;COSMIC	5.915	Down-regulation
CMGC_MAPK_p38_MAPK14_ST	P29353	SHC1	Q16539	MAPK14	S139	P144S	144	Missense	distal	5	no	8.842	9.292	EPSD	ICGC;COSMIC	5.915	Up-regulation
CMGC_MAPK_p38_MAPK14_ST	P29353	SHC1	Q16539	MAPK14	S139	R136S	136	Missense	distal	-3	no	8.842	8.329	EPSD	ICGC	5.915	Down-regulation
CMGC_MAPK_p38_MAPK14_ST	P29353	SHC1	Q16539	MAPK14	S139	H137Q	137	Missense	proximal	-2	no	8.842	10.093	EPSD	ICGC	5.915	Up-regulation
CMGC_MAPK_p38_MAPK14_ST	P29353	SHC1	Q16539	MAPK14	S139	R136L	136	Missense	distal	-3	no	8.842	6.598	EPSD	ICGC;COSMIC	5.915	Down-regulation
CMGC_MAPK_p38_MAPK14_ST	Q86UR1	NOXA1	Q16539	MAPK14	S282	P283Q	283	Missense	proximal	1	no	10.991	3.783	EPSD;PhosphoSitePlus	ICGC;COSMIC	5.915	Loss
CMGC_MAPK_p38_MAPK14_ST	P41212	ETV6	Q16539	MAPK14	T4	C8F	8	Missense	distal	4	no	9.364	8.941	EPSD	ICGC	5.915	Down-regulation
CMGC_MAPK_p38_MAPK14_ST	P41212	ETV6	Q16539	MAPK14	T18	P20S	20	Missense	proximal	2	no	6.916	7.293	EPSD	ICGC;COSMIC	5.915	Up-regulation
CMGC_MAPK_p38_MAPK14_ST	P41212	ETV6	Q16539	MAPK14	T18	P20Q	20	Missense	proximal	2	no	6.916	6.721	EPSD	ICGC;COSMIC	5.915	Down-regulation
CMGC_MAPK_p38_MAPK14_ST	P41212	ETV6	Q16539	MAPK14	T18	P25L	25	Missense	distal	7	no	6.916	6.753	EPSD	ICGC;COSMIC	5.915	Down-regulation
CMGC_MAPK_p38_MAPK14_ST	P41212	ETV6	Q16539	MAPK14	T18	E13K	13	Missense	distal	-5	no	6.916	7.250	EPSD	ICGC	5.915	Up-regulation
CMGC_MAPK_p38_MAPK14_ST	P41212	ETV6	Q16539	MAPK14	T18	P19S	19	Missense	proximal	1	no	6.916	-0.368	EPSD	ICGC;COSMIC	5.915	Loss
CMGC_MAPK_p38_MAPK14_ST	P41212	ETV6	Q16539	MAPK14	T18	S16L	16	Missense	proximal	-2	no	6.916	6.025	EPSD	ICGC;COSMIC	5.915	Down-regulation
CMGC_MAPK_p38_MAPK14_ST	P41212	ETV6	Q16539	MAPK14	S22	P20S	20	Missense	proximal	-2	no	12.051	11.563	EPSD;PhosphoSitePlus	ICGC;COSMIC	5.915	Down-regulation
CMGC_MAPK_p38_MAPK14_ST	P41212	ETV6	Q16539	MAPK14	S22	P20Q	20	Missense	proximal	-2	no	12.051	11.036	EPSD;PhosphoSitePlus	ICGC;COSMIC	5.915	Down-regulation
CMGC_MAPK_p38_MAPK14_ST	P41212	ETV6	Q16539	MAPK14	S22	P25L	25	Missense	distal	3	no	12.051	12.085	EPSD;PhosphoSitePlus	ICGC;COSMIC	5.915	Up-regulation
CMGC_MAPK_p38_MAPK14_ST	P41212	ETV6	Q16539	MAPK14	S22	P19S	19	Missense	distal	-3	no	12.051	12.815	EPSD;PhosphoSitePlus	ICGC;COSMIC	5.915	Up-regulation
CMGC_MAPK_p38_MAPK14_ST	P41212	ETV6	Q16539	MAPK14	S22	A28S	28	Missense	distal	6	no	12.051	11.996	EPSD;PhosphoSitePlus	ICGC;COSMIC	5.915	Down-regulation
CMGC_MAPK_p38_MAPK14_ST	P41212	ETV6	Q16539	MAPK14	S22	S16L	16	Missense	distal	-6	no	12.051	10.831	EPSD;PhosphoSitePlus	ICGC;COSMIC	5.915	Down-regulation
CMGC_MAPK_p38_MAPK14_ST	P41212	ETV6	Q16539	MAPK14	T31	P25L	25	Missense	distal	-6	no	8.234	7.621	EPSD	ICGC;COSMIC	5.915	Down-regulation
CMGC_MAPK_p38_MAPK14_ST	P41212	ETV6	Q16539	MAPK14	T31	A28S	28	Missense	distal	-3	no	8.234	8.646	EPSD	ICGC;COSMIC	5.915	Up-regulation
CMGC_MAPK_p38_MAPK14_ST	P41212	ETV6	Q16539	MAPK14	T31	V37M	37	Missense	distal	6	no	8.234	8.523	EPSD	ICGC;COSMIC	5.915	Up-regulation
CMGC_MAPK_p38_MAPK14_ST	P41212	ETV6	Q16539	MAPK14	S131	H135R	135	Missense	distal	4	no	10.736	11.130	EPSD	ICGC;COSMIC	5.915	Up-regulation
CMGC_MAPK_p38_MAPK14_ST	P41212	ETV6	Q16539	MAPK14	T161	E154D	154	Missense	distal	-7	no	8.711	8.130	EPSD	ICGC;COSMIC	5.915	Down-regulation
CMGC_MAPK_p38_MAPK14_ST	P41212	ETV6	Q16539	MAPK14	T161	D155N	155	Missense	distal	-6	no	8.711	9.037	EPSD	ICGC;GDSC	5.915	Up-regulation
CMGC_MAPK_p38_MAPK14_ST	P41212	ETV6	Q16539	MAPK14	S184	H190R	190	Missense	distal	6	no	12.096	12.204	EPSD	ICGC	5.915	Up-regulation
CMGC_MAPK_p38_MAPK14_ST	P41212	ETV6	Q16539	MAPK14	S184	R191L	191	Missense	distal	7	no	12.096	11.677	EPSD	ICGC;COSMIC	5.915	Down-regulation
CMGC_MAPK_p38_MAPK14_ST	P41212	ETV6	Q16539	MAPK14	S184	R183S	183	Missense	proximal	-1	no	12.096	12.204	EPSD	ICGC	5.915	Up-regulation
CMGC_MAPK_p38_MAPK14_ST	P41212	ETV6	Q16539	MAPK14	S184	R181H	181	Missense	distal	-3	no	12.096	10.343	EPSD	ICGC;GDSC	5.915	Down-regulation
CMGC_MAPK_p38_MAPK14_ST	P41212	ETV6	Q16539	MAPK14	S193	E197K	197	Missense	distal	4	no	12.269	11.803	EPSD	ICGC;COSMIC	5.915	Down-regulation
CMGC_MAPK_p38_MAPK14_ST	P41212	ETV6	Q16539	MAPK14	S193	H190R	190	Missense	distal	-3	no	12.269	14.023	EPSD	ICGC	5.915	Up-regulation
CMGC_MAPK_p38_MAPK14_ST	P41212	ETV6	Q16539	MAPK14	S193	R191L	191	Missense	proximal	-2	no	12.269	11.578	EPSD	ICGC;COSMIC	5.915	Down-regulation
CMGC_MAPK_p38_MAPK14_ST	P41212	ETV6	Q16539	MAPK14	S203	R202W	202	Missense	proximal	-1	no	9.812	10.100	EPSD	ICGC;COSMIC;CCLE	5.915	Up-regulation
CMGC_MAPK_p38_MAPK14_ST	P41212	ETV6	Q16539	MAPK14	S203	R210H	210	Missense	distal	7	no	9.812	9.278	EPSD	ICGC;COSMIC	5.915	Down-regulation
CMGC_MAPK_p38_MAPK14_ST	P41212	ETV6	Q16539	MAPK14	S203	E197K	197	Missense	distal	-6	no	9.812	9.398	EPSD	ICGC;COSMIC	5.915	Down-regulation
CMGC_MAPK_p38_MAPK14_ST	P41212	ETV6	Q16539	MAPK14	S213	E216K	216	Missense	distal	3	no	9.084	9.132	EPSD	ICGC	5.915	Up-regulation
CMGC_MAPK_p38_MAPK14_ST	P41212	ETV6	Q16539	MAPK14	S213	R210H	210	Missense	distal	-3	no	9.084	7.330	EPSD	ICGC;COSMIC	5.915	Down-regulation
CMGC_MAPK_p38_MAPK14_ST	P41212	ETV6	Q16539	MAPK14	S213	Q219H	219	Missense	distal	6	no	9.084	8.965	EPSD	ICGC;COSMIC	5.915	Down-regulation
CMGC_MAPK_p38_MAPK14_ST	P41212	ETV6	Q16539	MAPK14	S238	P239L	239	Missense	proximal	1	no	11.284	3.233	EPSD	ICGC	5.915	Loss
CMGC_MAPK_p38_MAPK14_ST	P41212	ETV6	Q16539	MAPK14	S257	R264C	264	Missense	distal	7	no	13.479	12.879	PhosphoSitePlus;EPSD	ICGC;COSMIC	5.915	Down-regulation
CMGC_MAPK_p38_MAPK14_ST	P41212	ETV6	Q16539	MAPK14	S257	R264H	264	Missense	distal	7	no	13.479	12.945	PhosphoSitePlus;EPSD	ICGC	5.915	Down-regulation
CMGC_MAPK_p38_MAPK14_ST	P41212	ETV6	Q16539	MAPK14	S257	E250D	250	Missense	distal	-7	no	13.479	12.897	PhosphoSitePlus;EPSD	ICGC;COSMIC	5.915	Down-regulation
CMGC_MAPK_p38_MAPK14_ST	P41212	ETV6	Q16539	MAPK14	S271	R264C	264	Missense	distal	-7	no	7.629	7.237	EPSD	ICGC;COSMIC	5.915	Down-regulation
CMGC_MAPK_p38_MAPK14_ST	P41212	ETV6	Q16539	MAPK14	S271	R264H	264	Missense	distal	-7	no	7.629	7.334	EPSD	ICGC	5.915	Down-regulation
CMGC_MAPK_p38_MAPK14_ST	P41212	ETV6	Q16539	MAPK14	S323	E326Q	326	Missense	distal	3	no	9.215	9.288	EPSD	ICGC;COSMIC	5.915	Up-regulation
CMGC_MAPK_p38_MAPK14_ST	P41212	ETV6	Q16539	MAPK14	T422	G429D	429	Missense	distal	7	no	7.739	7.905	EPSD	ICGC;COSMIC	5.915	Up-regulation
CMGC_MAPK_p38_MAPK14_ST	P41212	ETV6	Q16539	MAPK14	T422	R418S	418	Missense	distal	-4	no	7.739	7.728	EPSD	ICGC;COSMIC	5.915	Down-regulation
CMGC_MAPK_p38_MAPK14_ST	P41212	ETV6	Q16539	MAPK14	T422	L415F	415	Missense	distal	-7	no	7.739	7.274	EPSD	ICGC	5.915	Down-regulation
CMGC_MAPK_p38_MAPK14_ST	P41212	ETV6	Q16539	MAPK14	T431	D432H	432	Missense	proximal	1	no	6.316	0.094	EPSD	ICGC;COSMIC	5.915	Loss
CMGC_MAPK_p38_MAPK14_ST	P41212	ETV6	Q16539	MAPK14	T431	E438D	438	Missense	distal	7	no	6.316	6.122	EPSD	ICGC	5.915	Down-regulation
CMGC_MAPK_p38_MAPK14_ST	P41212	ETV6	Q16539	MAPK14	T431	G429D	429	Missense	proximal	-2	no	6.316	5.566	EPSD	ICGC;COSMIC	5.915	Loss
CMGC_MAPK_p38_MAPK14_ST	P19419	ELK1	Q16539	MAPK14	T133	T133K	133	Missense	central	0	yes	8.653	0.000	EPSD	ICGC	5.915	Loss
CMGC_MAPK_p38_MAPK14_ST	P19419	ELK1	Q16539	MAPK14	S304	G299S	299	Missense	distal	-5	no	11.437	11.056	EPSD	ICGC;COSMIC	5.915	Down-regulation
CMGC_MAPK_p38_MAPK14_ST	P19419	ELK1	Q16539	MAPK14	S304	A297G	297	Missense	distal	-7	no	11.437	11.257	EPSD	ICGC	5.915	Down-regulation
CMGC_MAPK_p38_MAPK14_ST	P19419	ELK1	Q16539	MAPK14	S324	S326I	326	Missense	proximal	2	no	11.186	10.707	EPSD	ICGC	5.915	Down-regulation
CMGC_MAPK_p38_MAPK14_ST	P19419	ELK1	Q16539	MAPK14	T353	P348S	348	Missense	distal	-5	no	9.167	8.719	EPSD	ICGC	5.915	Down-regulation
CMGC_MAPK_p38_MAPK14_ST	P19419	ELK1	Q16539	MAPK14	T363	T368K	368	Missense	distal	5	no	10.509	10.071	EPSD	ICGC	5.915	Down-regulation
CMGC_MAPK_p38_MAPK14_ST	P19419	ELK1	Q16539	MAPK14	T363	P364L	364	Missense	proximal	1	no	10.509	2.459	EPSD	ICGC;COSMIC	5.915	Loss
CMGC_MAPK_p38_MAPK14_ST	P19419	ELK1	Q16539	MAPK14	T368	T368K	368	Missense	central	0	yes	6.828	0.000	EPSD	ICGC	5.915	Loss
CMGC_MAPK_p38_MAPK14_ST	P19419	ELK1	Q16539	MAPK14	T368	P364L	364	Missense	distal	-4	no	6.828	7.340	EPSD	ICGC;COSMIC	5.915	Up-regulation
CMGC_MAPK_p38_MAPK14_ST	P19419	ELK1	Q16539	MAPK14	T368	S371L	371	Missense	distal	3	no	6.828	6.902	EPSD	ICGC;COSMIC	5.915	Up-regulation
CMGC_MAPK_p38_MAPK14_ST	P19419	ELK1	Q16539	MAPK14	S383	P390L	390	Missense	distal	7	no	11.683	11.520	EPSD;PhosphoSitePlus	ICGC;COSMIC	5.915	Down-regulation
CMGC_MAPK_p38_MAPK14_ST	P19419	ELK1	Q16539	MAPK14	S383	S380R	380	Missense	distal	-3	no	11.683	12.195	EPSD;PhosphoSitePlus	ICGC	5.915	Up-regulation
CMGC_MAPK_p38_MAPK14_ST	P19419	ELK1	Q16539	MAPK14	S383	H377N	377	Missense	distal	-6	no	11.683	12.329	EPSD;PhosphoSitePlus	ICGC	5.915	Up-regulation
CMGC_MAPK_p38_MAPK14_ST	P19419	ELK1	Q16539	MAPK14	S383	R388H	388	Missense	distal	5	no	11.683	10.988	EPSD;PhosphoSitePlus	ICGC;COSMIC	5.915	Down-regulation
CMGC_MAPK_p38_MAPK14_ST	P19419	ELK1	Q16539	MAPK14	S389	P390L	390	Missense	proximal	1	no	13.211	5.160	PhosphoSitePlus;EPSD	ICGC;COSMIC	5.915	Loss
CMGC_MAPK_p38_MAPK14_ST	P19419	ELK1	Q16539	MAPK14	S389	R388H	388	Missense	proximal	-1	no	13.211	13.366	PhosphoSitePlus;EPSD	ICGC;COSMIC	5.915	Up-regulation
CMGC_MAPK_p38_MAPK14_ST	P21462	FPR1	Q16539	MAPK14	S332	D333N	333	Missense	proximal	1	no	6.497	6.125	EPSD	ICGC;COSMIC	5.915	Down-regulation
CMGC_MAPK_p38_MAPK14_ST	P21462	FPR1	Q16539	MAPK14	S332	S328A	328	Missense	distal	-4	no	6.497	6.537	EPSD	ICGC;COSMIC	5.915	Up-regulation
CMGC_MAPK_p38_MAPK14_ST	P21462	FPR1	Q16539	MAPK14	S332	E326D	326	Missense	distal	-6	no	6.497	5.919	EPSD	ICGC;COSMIC	5.915	Down-regulation
CMGC_MAPK_p38_MAPK14_ST	P21462	FPR1	Q16539	MAPK14	S338	D333N	333	Missense	distal	-5	no	6.555	6.395	EPSD	ICGC;COSMIC	5.915	Down-regulation
CMGC_MAPK_p38_MAPK14_ST	P21462	FPR1	Q16539	MAPK14	S338	S342Y	342	Missense	distal	4	no	6.555	5.508	EPSD	ICGC	5.915	Loss
CMGC_MAPK_p38_MAPK14_ST	P21462	FPR1	Q16539	MAPK14	S342	E346A	346	Missense	distal	4	no	6.506	5.700	PhosphoSitePlus	ICGC;COSMIC	5.915	Loss
CMGC_MAPK_p38_MAPK14_ST	P21462	FPR1	Q16539	MAPK14	S342	Q348H	348	Missense	distal	6	no	6.506	6.387	PhosphoSitePlus	ICGC	5.915	Down-regulation
CMGC_MAPK_p38_MAPK14_ST	P21462	FPR1	Q16539	MAPK14	S342	S342Y	342	Missense	central	0	yes	6.506	0.000	PhosphoSitePlus	ICGC	5.915	Loss
CMGC_MAPK_p38_MAPK14_ST	Q9UBK2	PPARGC1A	Q16539	MAPK14	S208	S208L	208	Missense	central	0	yes	6.703	0.000	EPSD	ICGC;COSMIC;GDSC	5.915	Loss
CMGC_MAPK_p38_MAPK14_ST	Q9UBK2	PPARGC1A	Q16539	MAPK14	S208	P206T	206	Missense	proximal	-2	no	6.703	5.984	EPSD	ICGC;COSMIC	5.915	Down-regulation
CMGC_MAPK_p38_MAPK14_ST	Q9UBK2	PPARGC1A	Q16539	MAPK14	S208	P206R	206	Missense	proximal	-2	no	6.703	6.015	EPSD	ICGC;COSMIC	5.915	Down-regulation
CMGC_MAPK_p38_MAPK14_ST	Q9UBK2	PPARGC1A	Q16539	MAPK14	S208	E209K	209	Missense	proximal	1	no	6.703	5.455	EPSD	ICGC	5.915	Loss
CMGC_MAPK_p38_MAPK14_ST	Q9UBK2	PPARGC1A	Q16539	MAPK14	S208	P206H	206	Missense	proximal	-2	no	6.703	4.437	EPSD	ICGC;COSMIC	5.915	Loss
CMGC_MAPK_p38_MAPK14_ST	Q9UBK2	PPARGC1A	Q16539	MAPK14	S208	K201N	201	Missense	distal	-7	no	6.703	6.396	EPSD	ICGC;COSMIC	5.915	Down-regulation
CMGC_MAPK_p38_MAPK14_ST	Q9UBK2	PPARGC1A	Q16539	MAPK14	T263	P267Q	267	Missense	distal	4	no	10.737	10.255	PhosphoSitePlus;EPSD	ICGC	5.915	Down-regulation
CMGC_MAPK_p38_MAPK14_ST	Q9UBK2	PPARGC1A	Q16539	MAPK14	S266	P267Q	267	Missense	proximal	1	no	12.144	4.935	EPSD;PhosphoSitePlus	ICGC	5.915	Loss
CMGC_MAPK_p38_MAPK14_ST	Q9UBK2	PPARGC1A	Q16539	MAPK14	S266	K271N	271	Missense	distal	5	no	12.144	12.413	EPSD;PhosphoSitePlus	ICGC;COSMIC	5.915	Up-regulation
CMGC_MAPK_p38_MAPK14_ST	Q9UBK2	PPARGC1A	Q16539	MAPK14	S273	P267Q	267	Missense	distal	-6	no	10.394	10.225	EPSD	ICGC	5.915	Down-regulation
CMGC_MAPK_p38_MAPK14_ST	Q9UBK2	PPARGC1A	Q16539	MAPK14	S273	I280T	280	Missense	distal	7	no	10.394	10.806	EPSD	ICGC;COSMIC	5.915	Up-regulation
CMGC_MAPK_p38_MAPK14_ST	Q9UBK2	PPARGC1A	Q16539	MAPK14	S273	K271N	271	Missense	proximal	-2	no	10.394	10.511	EPSD	ICGC;COSMIC	5.915	Up-regulation
CMGC_MAPK_p38_MAPK14_ST	Q9UBK2	PPARGC1A	Q16539	MAPK14	T295	H302N	302	Missense	distal	7	no	10.068	10.269	EPSD	ICGC;COSMIC	5.915	Up-regulation
CMGC_MAPK_p38_MAPK14_ST	Q9UBK2	PPARGC1A	Q16539	MAPK14	T299	K303E	303	Missense	distal	4	no	12.244	12.710	EPSD;PhosphoSitePlus	ICGC;COSMIC	5.915	Up-regulation
CMGC_MAPK_p38_MAPK14_ST	Q9UBK2	PPARGC1A	Q16539	MAPK14	T299	H302N	302	Missense	distal	3	no	12.244	12.191	EPSD;PhosphoSitePlus	ICGC;COSMIC	5.915	Down-regulation
CMGC_MAPK_p38_MAPK14_ST	Q9UBK2	PPARGC1A	Q16539	MAPK14	S313	A312D	312	Missense	proximal	-1	no	10.028	10.225	EPSD	ICGC	5.915	Up-regulation
CMGC_MAPK_p38_MAPK14_ST	Q9UBK2	PPARGC1A	Q16539	MAPK14	S313	L316M	316	Missense	distal	3	no	10.028	9.992	EPSD	ICGC	5.915	Down-regulation
CMGC_MAPK_p38_MAPK14_ST	Q9UBK2	PPARGC1A	Q16539	MAPK14	S552	S556F	556	Missense	distal	4	no	9.770	8.196	EPSD	ICGC	5.915	Down-regulation
CMGC_MAPK_p38_MAPK14_ST	Q9UBK2	PPARGC1A	Q16539	MAPK14	S573	R568C	568	Missense	distal	-5	no	5.478	5.960	EPSD	ICGC;COSMIC	5.915	Gain
CMGC_MAPK_p38_MAPK14_ST	Q9UBK2	PPARGC1A	Q16539	MAPK14	S573	R574Q	574	Missense	proximal	1	no	5.478	6.205	EPSD	ICGC;COSMIC	5.915	Gain
CMGC_MAPK_p38_MAPK14_ST	Q9UBK2	PPARGC1A	Q16539	MAPK14	S581	R580Q	580	Missense	proximal	-1	no	6.410	6.498	EPSD	ICGC;COSMIC	5.915	Up-regulation
CMGC_MAPK_p38_MAPK14_ST	Q9UBK2	PPARGC1A	Q16539	MAPK14	S581	S579F	579	Missense	proximal	-2	no	6.410	5.686	EPSD	ICGC;COSMIC	5.915	Loss
CMGC_MAPK_p38_MAPK14_ST	Q9UBK2	PPARGC1A	Q16539	MAPK14	S581	R574Q	574	Missense	distal	-7	no	6.410	6.316	EPSD	ICGC;COSMIC	5.915	Down-regulation
CMGC_MAPK_p38_MAPK14_ST	Q9UBK2	PPARGC1A	Q16539	MAPK14	S581	S577L	577	Missense	distal	-4	no	6.410	7.009	EPSD	ICGC;COSMIC;GDSC	5.915	Up-regulation
CMGC_MAPK_p38_MAPK14_ST	Q9UBK2	PPARGC1A	Q16539	MAPK14	S581	S588L	588	Missense	distal	7	no	6.410	6.025	EPSD	ICGC	5.915	Down-regulation
CMGC_MAPK_p38_MAPK14_ST	Q9UBK2	PPARGC1A	Q16539	MAPK14	S586	R580Q	580	Missense	distal	-6	no	6.449	5.779	EPSD	ICGC;COSMIC	5.915	Loss
CMGC_MAPK_p38_MAPK14_ST	Q9UBK2	PPARGC1A	Q16539	MAPK14	S586	S579F	579	Missense	distal	-7	no	6.449	5.703	EPSD	ICGC;COSMIC	5.915	Loss
CMGC_MAPK_p38_MAPK14_ST	Q9UBK2	PPARGC1A	Q16539	MAPK14	S586	S588L	588	Missense	proximal	2	no	6.449	5.960	EPSD	ICGC	5.915	Down-regulation
CMGC_MAPK_p38_MAPK14_ST	Q9UBK2	PPARGC1A	Q16539	MAPK14	S590	S588L	588	Missense	proximal	-2	no	12.770	11.879	EPSD	ICGC	5.915	Down-regulation
CMGC_MAPK_p38_MAPK14_ST	Q9UBK2	PPARGC1A	Q16539	MAPK14	S593	S588L	588	Missense	distal	-5	no	7.958	8.688	EPSD	ICGC	5.915	Up-regulation
CMGC_MAPK_p38_MAPK14_ST	Q9UBK2	PPARGC1A	Q16539	MAPK14	S616	R611H	611	Missense	distal	-5	no	9.507	10.050	EPSD	ICGC;COSMIC	5.915	Up-regulation
CMGC_MAPK_p38_MAPK14_ST	Q9UBK2	PPARGC1A	Q16539	MAPK14	S616	T612M	612	Missense	distal	-4	no	9.507	9.301	EPSD	ICGC;COSMIC	5.915	Down-regulation
CMGC_MAPK_p38_MAPK14_ST	Q9UBK2	PPARGC1A	Q16539	MAPK14	S616	P617S	617	Missense	proximal	1	no	9.507	2.223	EPSD	ICGC;COSMIC	5.915	Loss
CMGC_MAPK_p38_MAPK14_ST	Q9UBK2	PPARGC1A	Q16539	MAPK14	S616	N615T	615	Missense	proximal	-1	no	9.507	9.552	EPSD	ICGC;COSMIC	5.915	Up-regulation
CMGC_MAPK_p38_MAPK14_ST	Q9UBK2	PPARGC1A	Q16539	MAPK14	S626	R630C	630	Missense	distal	4	no	8.968	8.534	EPSD	ICGC;COSMIC	5.915	Down-regulation
CMGC_MAPK_p38_MAPK14_ST	Q9UBK2	PPARGC1A	Q16539	MAPK14	S626	R625T	625	Missense	proximal	-1	no	8.968	9.192	EPSD	ICGC;GDSC;CCLE	5.915	Up-regulation
CMGC_MAPK_p38_MAPK14_ST	P49841	GSK3B	Q16539	MAPK14	S9	A11S	11	Missense	proximal	2	no	6.613	6.876	EPSD	ICGC;COSMIC	5.915	Up-regulation
CMGC_MAPK_p38_MAPK14_ST	P49841	GSK3B	Q16539	MAPK14	T43	D49E	49	Missense	distal	6	no	9.712	9.813	EPSD	ICGC	5.915	Up-regulation
CMGC_MAPK_p38_MAPK14_ST	P49841	GSK3B	Q16539	MAPK14	S215	P212T	212	Missense	distal	-3	no	5.850	6.296	EPSD	ICGC	5.915	Gain
CMGC_MAPK_p38_MAPK14_ST	P49841	GSK3B	Q16539	MAPK14	T275	I270V	270	Missense	distal	-5	no	8.466	8.670	EPSD	ICGC;COSMIC	5.915	Up-regulation
CMGC_MAPK_p38_MAPK14_ST	P49841	GSK3B	Q16539	MAPK14	T275	R278K	278	Missense	distal	3	no	8.466	8.482	EPSD	ICGC	5.915	Up-regulation
CMGC_MAPK_p38_MAPK14_ST	P49841	GSK3B	Q16539	MAPK14	T275	L273R	273	Missense	proximal	-2	no	8.466	9.157	EPSD	ICGC	5.915	Up-regulation
CMGC_MAPK_p38_MAPK14_ST	P49841	GSK3B	Q16539	MAPK14	T275	L273M	273	Missense	proximal	-2	no	8.466	9.034	EPSD	ICGC;COSMIC	5.915	Up-regulation
CMGC_MAPK_p38_MAPK14_ST	P49841	GSK3B	Q16539	MAPK14	T324	R319H	319	Missense	distal	-5	no	8.820	9.363	EPSD	ICGC;COSMIC	5.915	Up-regulation
CMGC_MAPK_p38_MAPK14_ST	P49841	GSK3B	Q16539	MAPK14	T324	A327P	327	Missense	distal	3	no	8.820	8.845	EPSD	ICGC;COSMIC	5.915	Up-regulation
CMGC_MAPK_p38_MAPK14_ST	P49841	GSK3B	Q16539	MAPK14	T324	R328L	328	Missense	distal	4	no	8.820	8.458	EPSD	ICGC;COSMIC	5.915	Down-regulation
CMGC_MAPK_p38_MAPK14_ST	P49841	GSK3B	Q16539	MAPK14	T324	P331L	331	Missense	distal	7	no	8.820	8.657	EPSD	ICGC;COSMIC	5.915	Down-regulation
CMGC_MAPK_p38_MAPK14_ST	P49841	GSK3B	Q16539	MAPK14	T324	R328Q	328	Missense	distal	4	no	8.820	8.616	EPSD	ICGC	5.915	Down-regulation
CMGC_MAPK_p38_MAPK14_ST	P49841	GSK3B	Q16539	MAPK14	T324	L321M	321	Missense	distal	-3	no	8.820	9.128	EPSD	ICGC;COSMIC	5.915	Up-regulation
CMGC_MAPK_p38_MAPK14_ST	P49841	GSK3B	Q16539	MAPK14	S389	S389P	389	Missense	central	0	yes	5.959	0.000	EPSD;PhosphoSitePlus	ICGC;COSMIC	5.915	Loss
CMGC_MAPK_p38_MAPK14_ST	P49841	GSK3B	Q16539	MAPK14	S389	R383Q	383	Missense	distal	-6	no	5.959	5.289	EPSD;PhosphoSitePlus	ICGC;COSMIC	5.915	Loss
CMGC_MAPK_p38_MAPK14_ST	P49841	GSK3B	Q16539	MAPK14	T390	S389P	389	Missense	proximal	-1	no	10.297	10.389	PhosphoSitePlus;EPSD	ICGC;COSMIC	5.915	Up-regulation
CMGC_MAPK_p38_MAPK14_ST	P49841	GSK3B	Q16539	MAPK14	T390	A397T	397	Missense	distal	7	no	10.297	9.954	PhosphoSitePlus;EPSD	ICGC;COSMIC	5.915	Down-regulation
CMGC_MAPK_p38_MAPK14_ST	P49841	GSK3B	Q16539	MAPK14	T390	R383Q	383	Missense	distal	-7	no	10.297	10.203	PhosphoSitePlus;EPSD	ICGC;COSMIC	5.915	Down-regulation
CMGC_MAPK_p38_MAPK14_ST	P49841	GSK3B	Q16539	MAPK14	T408	G406R	406	Missense	proximal	-2	no	6.839	7.089	EPSD	ICGC;COSMIC	5.915	Up-regulation
CMGC_MAPK_p38_MAPK14_ST	P49841	GSK3B	Q16539	MAPK14	T408	S415T	415	Missense	distal	7	no	6.839	6.518	EPSD	ICGC;COSMIC	5.915	Down-regulation
CMGC_MAPK_p38_MAPK14_ST	P49841	GSK3B	Q16539	MAPK14	S413	G406R	406	Missense	distal	-7	no	6.983	6.881	EPSD	ICGC;COSMIC	5.915	Down-regulation
CMGC_MAPK_p38_MAPK14_ST	P49841	GSK3B	Q16539	MAPK14	S413	S415T	415	Missense	proximal	2	no	6.983	6.747	EPSD	ICGC;COSMIC	5.915	Down-regulation
CMGC_MAPK_p38_MAPK14_ST	O43526	KCNQ2	Q16539	MAPK14	S45	G51V	51	Missense	distal	6	no	6.123	5.762	EPSD	ICGC	5.915	Loss
CMGC_MAPK_p38_MAPK14_ST	O43526	KCNQ2	Q16539	MAPK14	S45	R50C	50	Missense	distal	5	no	6.123	5.253	EPSD	ICGC	5.915	Loss
CMGC_MAPK_p38_MAPK14_ST	O43526	KCNQ2	Q16539	MAPK14	S45	A47D	47	Missense	proximal	2	no	6.123	5.901	EPSD	ICGC	5.915	Loss
CMGC_MAPK_p38_MAPK14_ST	O43526	KCNQ2	Q16539	MAPK14	S45	A39P	39	Missense	distal	-6	no	6.123	6.059	EPSD	ICGC;COSMIC	5.915	Down-regulation
CMGC_MAPK_p38_MAPK14_ST	O43526	KCNQ2	Q16539	MAPK14	S457	A451T	451	Missense	distal	-6	no	8.506	8.776	EPSD	ICGC;COSMIC	5.915	Up-regulation
CMGC_MAPK_p38_MAPK14_ST	O43526	KCNQ2	Q16539	MAPK14	S485	S485L	485	Missense	central	0	yes	8.297	0.000	EPSD	ICGC;COSMIC	5.915	Loss
CMGC_MAPK_p38_MAPK14_ST	O43526	KCNQ2	Q16539	MAPK14	S855	P852S	852	Missense	distal	-3	no	5.455	6.218	EPSD	ICGC;COSMIC	5.915	Gain
CMGC_MAPK_p38_MAPK14_ST	Q9BUB5	MKNK1	Q16539	MAPK14	T385	K381N	381	Missense	distal	-4	no	8.427	8.573	EPSD	ICGC;COSMIC	5.915	Up-regulation
CMGC_MAPK_p38_MAPK14_ST	Q9Y6Q9	NCOA3	Q16539	MAPK14	T203	D210N	210	Missense	distal	7	no	6.895	6.573	EPSD	ICGC;COSMIC	5.915	Down-regulation
CMGC_MAPK_p38_MAPK14_ST	Q9Y6Q9	NCOA3	Q16539	MAPK14	S214	D210N	210	Missense	distal	-4	no	11.788	11.368	EPSD	ICGC;COSMIC	5.915	Down-regulation
CMGC_MAPK_p38_MAPK14_ST	Q9Y6Q9	NCOA3	Q16539	MAPK14	S465	H468L	468	Missense	distal	3	no	9.402	9.377	EPSD	ICGC;COSMIC	5.915	Down-regulation
CMGC_MAPK_p38_MAPK14_ST	Q9Y6Q9	NCOA3	Q16539	MAPK14	S470	H468L	468	Missense	proximal	-2	no	8.685	9.571	EPSD	ICGC;COSMIC	5.915	Up-regulation
CMGC_MAPK_p38_MAPK14_ST	Q9Y6Q9	NCOA3	Q16539	MAPK14	S505	S498F	498	Missense	distal	-7	no	11.775	11.029	EPSD;PhosphoSitePlus	ICGC;COSMIC	5.915	Down-regulation
CMGC_MAPK_p38_MAPK14_ST	Q9Y6Q9	NCOA3	Q16539	MAPK14	S543	L548W	548	Missense	distal	5	no	13.250	12.993	EPSD;PhosphoSitePlus	ICGC;COSMIC	5.915	Down-regulation
CMGC_MAPK_p38_MAPK14_ST	Q9Y6Q9	NCOA3	Q16539	MAPK14	S551	L548W	548	Missense	distal	-3	no	9.578	9.464	EPSD	ICGC;COSMIC	5.915	Down-regulation
CMGC_MAPK_p38_MAPK14_ST	Q9Y6Q9	NCOA3	Q16539	MAPK14	S569	D576Y	576	Missense	distal	7	no	9.494	9.513	EPSD	ICGC;COSMIC	5.915	Up-regulation
CMGC_MAPK_p38_MAPK14_ST	Q9Y6Q9	NCOA3	Q16539	MAPK14	S635	S635F	635	Missense	central	0	yes	6.837	0.000	EPSD	ICGC	5.915	Loss
CMGC_MAPK_p38_MAPK14_ST	Q9Y6Q9	NCOA3	Q16539	MAPK14	S640	S635F	635	Missense	distal	-5	no	11.405	12.190	EPSD	ICGC	5.915	Up-regulation
CMGC_MAPK_p38_MAPK14_ST	Q9Y6Q9	NCOA3	Q16539	MAPK14	S694	A696T	696	Missense	proximal	2	no	10.428	10.456	EPSD	ICGC	5.915	Up-regulation
CMGC_MAPK_p38_MAPK14_ST	Q9Y6Q9	NCOA3	Q16539	MAPK14	T702	A696T	696	Missense	distal	-6	no	6.084	6.354	EPSD	ICGC	5.915	Up-regulation
CMGC_MAPK_p38_MAPK14_ST	Q9Y6Q9	NCOA3	Q16539	MAPK14	T914	S917T	917	Missense	distal	3	no	10.161	10.174	EPSD	ICGC;COSMIC	5.915	Up-regulation
CMGC_MAPK_p38_MAPK14_ST	Q9Y6Q9	NCOA3	Q16539	MAPK14	T914	V911M	911	Missense	distal	-3	no	10.161	10.650	EPSD	ICGC;COSMIC	5.915	Up-regulation
CMGC_MAPK_p38_MAPK14_ST	Q9Y6Q9	NCOA3	Q16539	MAPK14	S1330	A1324S	1324	Missense	distal	-6	no	12.439	12.982	EPSD	ICGC	5.915	Up-regulation
CMGC_MAPK_p38_MAPK14_ST	P53667	LIMK1	Q16539	MAPK14	T270	L266M	266	Missense	distal	-4	no	6.217	5.689	EPSD	ICGC;COSMIC	5.915	Loss
CMGC_MAPK_p38_MAPK14_ST	P53667	LIMK1	Q16539	MAPK14	S271	L266M	266	Missense	distal	-5	no	12.125	11.548	EPSD	ICGC;COSMIC	5.915	Down-regulation
CMGC_MAPK_p38_MAPK14_ST	P53667	LIMK1	Q16539	MAPK14	S281	S287C	287	Missense	distal	6	no	7.526	7.251	EPSD	ICGC;COSMIC	5.915	Down-regulation
CMGC_MAPK_p38_MAPK14_ST	P53667	LIMK1	Q16539	MAPK14	S287	S287C	287	Missense	central	0	yes	5.939	0.000	EPSD	ICGC;COSMIC	5.915	Loss
CMGC_MAPK_p38_MAPK14_ST	P53667	LIMK1	Q16539	MAPK14	S302	R295Q	295	Missense	distal	-7	no	8.829	8.735	EPSD	ICGC;COSMIC	5.915	Down-regulation
CMGC_MAPK_p38_MAPK14_ST	Q15672	TWIST1	Q16539	MAPK14	S68	Q71R	71	Missense	distal	3	no	13.899	13.858	PhosphoSitePlus	ICGC	5.915	Down-regulation
CMGC_MAPK_p38_MAPK14_ST	Q15672	TWIST1	Q16539	MAPK14	S68	P66L	66	Missense	proximal	-2	no	13.899	12.519	PhosphoSitePlus	ICGC	5.915	Down-regulation
CMGC_MAPK_p38_MAPK14_ST	Q15672	TWIST1	Q16539	MAPK14	S68	G67A	67	Missense	proximal	-1	no	13.899	13.746	PhosphoSitePlus	ICGC	5.915	Down-regulation
CMGC_MAPK_p38_MAPK14_ST	Q15672	TWIST1	Q16539	MAPK14	S99	G92S	92	Missense	distal	-7	no	12.310	12.377	EPSD	ICGC;COSMIC;CCLE	5.915	Up-regulation
CMGC_MAPK_p38_MAPK14_ST	Q15672	TWIST1	Q16539	MAPK14	S99	S93G	93	Missense	distal	-6	no	12.310	11.829	EPSD	ICGC	5.915	Down-regulation
CMGC_MAPK_p38_MAPK14_ST	Q15672	TWIST1	Q16539	MAPK14	S99	S95G	95	Missense	distal	-4	no	12.310	12.308	EPSD	ICGC;COSMIC	5.915	Down-regulation
CMGC_MAPK_p38_MAPK14_ST	P49137	MAPKAPK2	Q16539	MAPK14	T214	T215P	215	Missense	proximal	1	no	2.368	9.822	EPSD	ICGC;COSMIC	5.915	Gain
CMGC_MAPK_p38_MAPK14_ST	P49137	MAPKAPK2	Q16539	MAPK14	T222	S216G	216	Missense	distal	-6	no	13.944	13.463	PhosphoSitePlus;EPSD	ICGC	5.915	Down-regulation
CMGC_MAPK_p38_MAPK14_ST	P49137	MAPKAPK2	Q16539	MAPK14	T222	T215P	215	Missense	distal	-7	no	13.944	13.926	PhosphoSitePlus;EPSD	ICGC;COSMIC	5.915	Down-regulation
CMGC_MAPK_p38_MAPK14_ST	P49137	MAPKAPK2	Q16539	MAPK14	T226	V230E	230	Missense	distal	4	no	9.442	10.682	EPSD	ICGC	5.915	Up-regulation
CMGC_MAPK_p38_MAPK14_ST	P49137	MAPKAPK2	Q16539	MAPK14	T334	P332H	332	Missense	proximal	-2	no	11.967	9.700	EPSD;PhosphoSitePlus	ICGC;COSMIC	5.915	Down-regulation
CMGC_MAPK_p38_MAPK14_ST	P52945	PDX1	Q16539	MAPK14	S66	E69K	69	Missense	distal	3	no	8.436	8.484	PhosphoSitePlus;EPSD	ICGC	5.915	Up-regulation
CMGC_MAPK_p38_MAPK14_ST	P19525	EIF2AK2	Q16539	MAPK14	S83	E78D	78	Missense	distal	-5	no	7.056	7.930	EPSD	ICGC	5.915	Up-regulation
CMGC_MAPK_p38_MAPK14_ST	P19525	EIF2AK2	Q16539	MAPK14	T90	G95A	95	Missense	distal	5	no	6.329	5.945	EPSD	ICGC;COSMIC	5.915	Down-regulation
CMGC_MAPK_p38_MAPK14_ST	P19525	EIF2AK2	Q16539	MAPK14	S181	T185A	185	Missense	distal	4	no	6.762	6.718	EPSD	ICGC;COSMIC	5.915	Down-regulation
CMGC_MAPK_p38_MAPK14_ST	P19525	EIF2AK2	Q16539	MAPK14	T451	T451N	451	Missense	central	0	yes	6.169	0.000	PhosphoSitePlus	ICGC	5.915	Loss
CMGC_MAPK_p38_MAPK14_ST	P19525	EIF2AK2	Q16539	MAPK14	S456	T451N	451	Missense	distal	-5	no	11.951	11.974	EPSD	ICGC	5.915	Up-regulation
CMGC_MAPK_p38_MAPK14_ST	P19525	EIF2AK2	Q16539	MAPK14	S456	Q459K	459	Missense	distal	3	no	11.951	11.926	EPSD	ICGC	5.915	Down-regulation
CMGC_MAPK_p38_MAPK14_ST	O75582	RPS6KA5	Q16539	MAPK14	S212	S212F	212	Missense	central	0	yes	6.531	0.000	EPSD	ICGC	5.915	Loss
CMGC_MAPK_p38_MAPK14_ST	O75582	RPS6KA5	Q16539	MAPK14	T353	N347S	347	Missense	distal	-6	no	6.747	7.170	EPSD	ICGC	5.915	Up-regulation
CMGC_MAPK_p38_MAPK14_ST	O75582	RPS6KA5	Q16539	MAPK14	S376	P380L	380	Missense	distal	4	no	5.976	5.337	EPSD	ICGC	5.915	Loss
CMGC_MAPK_p38_MAPK14_ST	O75582	RPS6KA5	Q16539	MAPK14	S691	P697H	697	Missense	distal	6	no	6.290	6.171	EPSD	ICGC	5.915	Down-regulation
CMGC_MAPK_p38_MAPK14_ST	O75582	RPS6KA5	Q16539	MAPK14	T700	P697H	697	Missense	distal	-3	no	11.163	10.685	EPSD	ICGC	5.915	Down-regulation
CMGC_MAPK_p38_MAPK14_ST	O75582	RPS6KA5	Q16539	MAPK14	T775	T774N	774	Missense	proximal	-1	no	7.480	7.435	EPSD	ICGC;COSMIC	5.915	Down-regulation
CMGC_MAPK_p38_MAPK14_ST	P43403	ZAP70	Q16539	MAPK14	S88	D90A	90	Missense	proximal	2	no	6.932	7.154	EPSD	ICGC;COSMIC	5.915	Up-regulation
CMGC_MAPK_p38_MAPK14_ST	P43403	ZAP70	Q16539	MAPK14	S88	P95L	95	Missense	distal	7	no	6.932	6.769	EPSD	ICGC;COSMIC	5.915	Down-regulation
CMGC_MAPK_p38_MAPK14_ST	P43403	ZAP70	Q16539	MAPK14	S88	R89H	89	Missense	proximal	1	no	6.932	1.213	EPSD	ICGC	5.915	Loss
CMGC_MAPK_p38_MAPK14_ST	P43403	ZAP70	Q16539	MAPK14	S88	C84Y	84	Missense	distal	-4	no	6.932	6.466	EPSD	ICGC;COSMIC	5.915	Down-regulation
CMGC_MAPK_p38_MAPK14_ST	P43403	ZAP70	Q16539	MAPK14	S167	R160Q	160	Missense	distal	-7	no	6.251	6.157	EPSD	ICGC;COSMIC	5.915	Down-regulation
CMGC_MAPK_p38_MAPK14_ST	P43403	ZAP70	Q16539	MAPK14	S167	P162S	162	Missense	distal	-5	no	6.251	5.803	EPSD	ICGC;COSMIC	5.915	Loss
CMGC_MAPK_p38_MAPK14_ST	P43403	ZAP70	Q16539	MAPK14	S167	A173S	173	Missense	distal	6	no	6.251	6.196	EPSD	ICGC	5.915	Down-regulation
CMGC_MAPK_p38_MAPK14_ST	P43403	ZAP70	Q16539	MAPK14	S167	M161I	161	Missense	distal	-6	no	6.251	5.816	EPSD	ICGC;COSMIC	5.915	Loss
CMGC_MAPK_p38_MAPK14_ST	P43403	ZAP70	Q16539	MAPK14	S167	R170L	170	Missense	distal	3	no	6.251	6.297	EPSD	ICGC;COSMIC	5.915	Up-regulation
CMGC_MAPK_p38_MAPK14_ST	P43403	ZAP70	Q16539	MAPK14	S167	E174K	174	Missense	distal	7	no	6.251	5.544	EPSD	ICGC;COSMIC	5.915	Loss
CMGC_MAPK_p38_MAPK14_ST	P43403	ZAP70	Q16539	MAPK14	S258	A259S	259	Missense	proximal	1	no	7.695	6.730	EPSD	ICGC	5.915	Down-regulation
CMGC_MAPK_p38_MAPK14_ST	P43403	ZAP70	Q16539	MAPK14	S258	S257I	257	Missense	proximal	-1	no	7.695	7.673	EPSD	ICGC	5.915	Down-regulation
CMGC_MAPK_p38_MAPK14_ST	P43403	ZAP70	Q16539	MAPK14	T293	T300M	300	Missense	distal	7	no	10.107	10.298	PhosphoSitePlus	ICGC;COSMIC;GDSC;CCLE	5.915	Up-regulation
CMGC_MAPK_p38_MAPK14_ST	P43403	ZAP70	Q16539	MAPK14	S301	T300M	300	Missense	proximal	-1	no	14.258	14.265	EPSD	ICGC;COSMIC;GDSC;CCLE	5.915	Up-regulation
CMGC_MAPK_p38_MAPK14_ST	P43403	ZAP70	Q16539	MAPK14	S301	D303G	303	Missense	proximal	2	no	14.258	14.515	EPSD	ICGC;COSMIC	5.915	Up-regulation
CMGC_MAPK_p38_MAPK14_ST	P43403	ZAP70	Q16539	MAPK14	T312	P318L	318	Missense	distal	6	no	6.237	6.098	EPSD	ICGC;COSMIC	5.915	Down-regulation
CMGC_MAPK_p38_MAPK14_ST	P43403	ZAP70	Q16539	MAPK14	S317	P318L	318	Missense	proximal	1	no	10.927	2.876	EPSD	ICGC;COSMIC	5.915	Loss
CMGC_MAPK_p38_MAPK14_ST	P43403	ZAP70	Q16539	MAPK14	T611	A616T	616	Missense	distal	5	no	5.462	5.935	EPSD	ICGC;COSMIC	5.915	Gain
CMGC_MAPK_p38_MAPK14_ST	P35236	PTPN7	Q16539	MAPK14	T30	Q24K	24	Missense	distal	-6	no	10.964	11.155	EPSD	ICGC;COSMIC	5.915	Up-regulation
CMGC_MAPK_p38_MAPK14_ST	P35236	PTPN7	Q16539	MAPK14	S93	Q88R	88	Missense	distal	-5	no	13.290	13.332	EPSD;PhosphoSitePlus	ICGC;COSMIC	5.915	Up-regulation
CMGC_MAPK_p38_MAPK14_ST	P27816	MAP4	Q16539	MAPK14	T76	T76N	76	Missense	central	0	yes	11.189	0.000	EPSD	ICGC	5.915	Loss
CMGC_MAPK_p38_MAPK14_ST	P27816	MAP4	Q16539	MAPK14	T76	P77L	77	Missense	proximal	1	no	11.189	3.138	EPSD	ICGC;COSMIC	5.915	Loss
CMGC_MAPK_p38_MAPK14_ST	P27816	MAP4	Q16539	MAPK14	S94	S94I	94	Missense	central	0	yes	6.361	0.000	EPSD	ICGC	5.915	Loss
CMGC_MAPK_p38_MAPK14_ST	P27816	MAP4	Q16539	MAPK14	S99	S94I	94	Missense	distal	-5	no	10.831	11.231	EPSD	ICGC	5.915	Up-regulation
CMGC_MAPK_p38_MAPK14_ST	P27816	MAP4	Q16539	MAPK14	S156	D161N	161	Missense	distal	5	no	5.908	6.116	EPSD	ICGC;COSMIC	5.915	Gain
CMGC_MAPK_p38_MAPK14_ST	P27816	MAP4	Q16539	MAPK14	S197	V192A	192	Missense	distal	-5	no	9.261	8.769	EPSD	ICGC;COSMIC	5.915	Down-regulation
CMGC_MAPK_p38_MAPK14_ST	P27816	MAP4	Q16539	MAPK14	S280	L284S	284	Missense	distal	4	no	9.941	11.019	EPSD	ICGC;COSMIC	5.915	Up-regulation
CMGC_MAPK_p38_MAPK14_ST	P27816	MAP4	Q16539	MAPK14	S280	T282A	282	Missense	proximal	2	no	9.941	9.912	EPSD	ICGC;COSMIC	5.915	Down-regulation
CMGC_MAPK_p38_MAPK14_ST	P27816	MAP4	Q16539	MAPK14	S358	S358Y	358	Missense	central	0	yes	9.205	0.000	EPSD	ICGC	5.915	Loss
CMGC_MAPK_p38_MAPK14_ST	P27816	MAP4	Q16539	MAPK14	S384	I386V	386	Missense	proximal	2	no	11.088	11.139	EPSD	ICGC;COSMIC	5.915	Up-regulation
CMGC_MAPK_p38_MAPK14_ST	P27816	MAP4	Q16539	MAPK14	S384	K387Q	387	Missense	distal	3	no	11.088	11.112	EPSD	ICGC	5.915	Up-regulation
CMGC_MAPK_p38_MAPK14_ST	P27816	MAP4	Q16539	MAPK14	S384	E381D	381	Missense	distal	-3	no	11.088	10.882	EPSD	ICGC;COSMIC	5.915	Down-regulation
CMGC_MAPK_p38_MAPK14_ST	P27816	MAP4	Q16539	MAPK14	T521	P524L	524	Missense	distal	3	no	11.676	11.710	EPSD	ICGC;COSMIC	5.915	Up-regulation
CMGC_MAPK_p38_MAPK14_ST	P27816	MAP4	Q16539	MAPK14	T521	P522Q	522	Missense	proximal	1	no	11.676	4.468	EPSD	ICGC	5.915	Loss
CMGC_MAPK_p38_MAPK14_ST	P27816	MAP4	Q16539	MAPK14	T571	V576G	576	Missense	distal	5	no	9.086	9.488	EPSD	ICGC;COSMIC	5.915	Up-regulation
CMGC_MAPK_p38_MAPK14_ST	P27816	MAP4	Q16539	MAPK14	S580	V576G	576	Missense	distal	-4	no	6.546	6.221	EPSD	ICGC;COSMIC	5.915	Down-regulation
CMGC_MAPK_p38_MAPK14_ST	P27816	MAP4	Q16539	MAPK14	S624	V628I	628	Missense	distal	4	no	10.181	10.132	EPSD	ICGC;COSMIC	5.915	Down-regulation
CMGC_MAPK_p38_MAPK14_ST	P27816	MAP4	Q16539	MAPK14	S624	A617S	617	Missense	distal	-7	no	10.181	10.068	EPSD	ICGC	5.915	Down-regulation
CMGC_MAPK_p38_MAPK14_ST	P27816	MAP4	Q16539	MAPK14	S659	P653Q	653	Missense	distal	-6	no	6.485	6.316	EPSD	ICGC	5.915	Down-regulation
CMGC_MAPK_p38_MAPK14_ST	P27816	MAP4	Q16539	MAPK14	S662	A669D	669	Missense	distal	7	no	8.246	8.247	EPSD	ICGC	5.915	Up-regulation
CMGC_MAPK_p38_MAPK14_ST	P27816	MAP4	Q16539	MAPK14	S662	A669V	669	Missense	distal	7	no	8.246	8.138	EPSD	ICGC;COSMIC	5.915	Down-regulation
CMGC_MAPK_p38_MAPK14_ST	P27816	MAP4	Q16539	MAPK14	S666	A669D	669	Missense	distal	3	no	6.032	6.068	EPSD	ICGC	5.915	Up-regulation
CMGC_MAPK_p38_MAPK14_ST	P27816	MAP4	Q16539	MAPK14	S666	A669V	669	Missense	distal	3	no	6.032	6.059	EPSD	ICGC;COSMIC	5.915	Up-regulation
CMGC_MAPK_p38_MAPK14_ST	P27816	MAP4	Q16539	MAPK14	T687	L693I	693	Missense	distal	6	no	9.097	9.013	EPSD	ICGC	5.915	Down-regulation
CMGC_MAPK_p38_MAPK14_ST	P27816	MAP4	Q16539	MAPK14	S696	L693I	693	Missense	distal	-3	no	13.579	13.238	PhosphoSitePlus;EPSD	ICGC	5.915	Down-regulation
CMGC_MAPK_p38_MAPK14_ST	P27816	MAP4	Q16539	MAPK14	S787	R785W	785	Missense	proximal	-2	no	11.725	11.199	EPSD;PhosphoSitePlus	ICGC;COSMIC	5.915	Down-regulation
CMGC_MAPK_p38_MAPK14_ST	P27816	MAP4	Q16539	MAPK14	T901	D905E	905	Missense	distal	4	no	8.464	10.133	EPSD	ICGC	5.915	Up-regulation
CMGC_MAPK_p38_MAPK14_ST	P27816	MAP4	Q16539	MAPK14	T901	P902T	902	Missense	proximal	1	no	8.464	1.010	EPSD	ICGC;COSMIC	5.915	Loss
CMGC_MAPK_p38_MAPK14_ST	P27816	MAP4	Q16539	MAPK14	T901	P902S	902	Missense	proximal	1	no	8.464	1.180	EPSD	ICGC	5.915	Loss
CMGC_MAPK_p38_MAPK14_ST	P27816	MAP4	Q16539	MAPK14	S1145	D1144E	1144	Missense	proximal	-1	no	7.107	6.763	EPSD	ICGC	5.915	Down-regulation
CMGC_MAPK_p38_MAPK14_ST	Q9H211	CDT1	Q16539	MAPK14	S79	P86S	86	Missense	distal	7	no	13.678	13.900	EPSD	ICGC	5.915	Up-regulation
CMGC_MAPK_p38_MAPK14_ST	Q9H211	CDT1	Q16539	MAPK14	S79	S79I	79	Missense	central	0	yes	13.678	0.000	EPSD	ICGC;COSMIC	5.915	Loss
CMGC_MAPK_p38_MAPK14_ST	Q9H211	CDT1	Q16539	MAPK14	T82	P86S	86	Missense	distal	4	no	9.524	9.963	EPSD	ICGC	5.915	Up-regulation
CMGC_MAPK_p38_MAPK14_ST	Q9H211	CDT1	Q16539	MAPK14	T82	S79I	79	Missense	distal	-3	no	9.524	7.452	EPSD	ICGC;COSMIC	5.915	Down-regulation
CMGC_MAPK_p38_MAPK14_ST	Q9H211	CDT1	Q16539	MAPK14	S93	P94T	94	Missense	proximal	1	no	10.051	2.598	EPSD	ICGC	5.915	Loss
CMGC_MAPK_p38_MAPK14_ST	Q9H211	CDT1	Q16539	MAPK14	S93	P86S	86	Missense	distal	-7	no	10.051	10.138	EPSD	ICGC	5.915	Up-regulation
CMGC_MAPK_p38_MAPK14_ST	Q9H211	CDT1	Q16539	MAPK14	S93	Q96K	96	Missense	distal	3	no	10.051	10.027	EPSD	ICGC;COSMIC	5.915	Down-regulation
CMGC_MAPK_p38_MAPK14_ST	Q9H211	CDT1	Q16539	MAPK14	T102	Q96K	96	Missense	distal	-6	no	9.473	9.664	EPSD	ICGC;COSMIC	5.915	Up-regulation
CMGC_MAPK_p38_MAPK14_ST	Q9H211	CDT1	Q16539	MAPK14	T152	A147S	147	Missense	distal	-5	no	11.586	11.474	EPSD	ICGC	5.915	Down-regulation
CMGC_MAPK_p38_MAPK14_ST	Q9H211	CDT1	Q16539	MAPK14	T213	P214L	214	Missense	proximal	1	no	9.181	1.130	EPSD	ICGC	5.915	Loss
CMGC_MAPK_p38_MAPK14_ST	Q9H211	CDT1	Q16539	MAPK14	S318	K311N	311	Missense	distal	-7	no	11.534	11.226	EPSD	ICGC	5.915	Down-regulation
CMGC_MAPK_p38_MAPK14_ST	Q9H211	CDT1	Q16539	MAPK14	S372	R368H	368	Missense	distal	-4	no	11.415	11.625	EPSD	ICGC	5.915	Up-regulation
CMGC_MAPK_p38_MAPK14_ST	Q9H211	CDT1	Q16539	MAPK14	S372	A378S	378	Missense	distal	6	no	11.415	11.360	EPSD	ICGC	5.915	Down-regulation
CMGC_MAPK_p38_MAPK14_ST	Q9H211	CDT1	Q16539	MAPK14	S386	P389H	389	Missense	distal	3	no	6.324	6.383	EPSD	ICGC	5.915	Up-regulation
CMGC_MAPK_p38_MAPK14_ST	Q9H211	CDT1	Q16539	MAPK14	S391	P389H	389	Missense	proximal	-2	no	11.410	9.144	PhosphoSitePlus;EPSD	ICGC	5.915	Down-regulation
CMGC_MAPK_p38_MAPK14_ST	Q9H211	CDT1	Q16539	MAPK14	S391	P395T	395	Missense	distal	4	no	11.410	11.588	PhosphoSitePlus;EPSD	ICGC;COSMIC	5.915	Up-regulation
CMGC_MAPK_p38_MAPK14_ST	Q9H211	CDT1	Q16539	MAPK14	S394	P389H	389	Missense	distal	-5	no	11.973	12.287	EPSD	ICGC	5.915	Up-regulation
CMGC_MAPK_p38_MAPK14_ST	Q9H211	CDT1	Q16539	MAPK14	S394	P395T	395	Missense	proximal	1	no	11.973	4.520	EPSD	ICGC;COSMIC	5.915	Loss
CMGC_MAPK_p38_MAPK14_ST	Q9H211	CDT1	Q16539	MAPK14	T402	T406P	406	Missense	distal	4	no	11.215	11.037	EPSD;PhosphoSitePlus	ICGC;COSMIC	5.915	Down-regulation
CMGC_MAPK_p38_MAPK14_ST	Q9H211	CDT1	Q16539	MAPK14	T402	P395T	395	Missense	distal	-7	no	11.215	11.233	EPSD;PhosphoSitePlus	ICGC;COSMIC	5.915	Up-regulation
CMGC_MAPK_p38_MAPK14_ST	Q9H211	CDT1	Q16539	MAPK14	T402	A405S	405	Missense	distal	3	no	11.215	11.201	EPSD;PhosphoSitePlus	ICGC	5.915	Down-regulation
CMGC_MAPK_p38_MAPK14_ST	Q9H211	CDT1	Q16539	MAPK14	T406	T406P	406	Missense	central	0	yes	11.078	0.000	EPSD;PhosphoSitePlus	ICGC;COSMIC	5.915	Loss
CMGC_MAPK_p38_MAPK14_ST	Q9H211	CDT1	Q16539	MAPK14	T406	A405S	405	Missense	proximal	-1	no	11.078	11.018	EPSD;PhosphoSitePlus	ICGC	5.915	Down-regulation
CMGC_MAPK_p38_MAPK14_ST	Q9H211	CDT1	Q16539	MAPK14	S411	T406P	406	Missense	distal	-5	no	10.413	10.420	EPSD;PhosphoSitePlus	ICGC;COSMIC	5.915	Up-regulation
CMGC_MAPK_p38_MAPK14_ST	Q9H211	CDT1	Q16539	MAPK14	S411	A405S	405	Missense	distal	-6	no	10.413	10.956	EPSD;PhosphoSitePlus	ICGC	5.915	Up-regulation
CMGC_MAPK_p38_MAPK14_ST	Q00613	HSF1	Q16539	MAPK14	S244	P239L	239	Missense	distal	-5	no	16.698	16.980	EPSD	ICGC;CCLE	5.915	Up-regulation
CMGC_MAPK_p38_MAPK14_ST	Q00613	HSF1	Q16539	MAPK14	S275	A278T	278	Missense	distal	3	no	14.111	14.110	EPSD	ICGC	5.915	Down-regulation
CMGC_MAPK_p38_MAPK14_ST	Q00613	HSF1	Q16539	MAPK14	S279	A278T	278	Missense	proximal	-1	no	10.463	10.519	EPSD	ICGC	5.915	Up-regulation
CMGC_MAPK_p38_MAPK14_ST	Q00613	HSF1	Q16539	MAPK14	S419	S421L	421	Missense	proximal	2	no	11.046	10.557	EPSD	ICGC;COSMIC	5.915	Down-regulation
CMGC_MAPK_p38_MAPK14_ST	Q00613	HSF1	Q16539	MAPK14	S419	S419G	419	Missense	central	0	yes	11.046	0.000	EPSD	ICGC;COSMIC	5.915	Loss
CMGC_MAPK_p38_MAPK14_ST	Q00613	HSF1	Q16539	MAPK14	S444	A437S	437	Missense	distal	-7	no	11.173	11.059	EPSD	ICGC;COSMIC	5.915	Down-regulation
CMGC_MAPK_p38_MAPK14_ST	P17844	DDX5	Q16539	MAPK14	T224	I229T	229	Missense	distal	5	no	7.441	8.367	EPSD	ICGC	5.915	Up-regulation
CMGC_MAPK_p38_MAPK14_ST	P17844	DDX5	Q16539	MAPK14	T224	I220V	220	Missense	distal	-4	no	7.441	7.596	EPSD	ICGC;COSMIC	5.915	Up-regulation
CMGC_MAPK_p38_MAPK14_ST	P17844	DDX5	Q16539	MAPK14	T446	V453A	453	Missense	distal	7	no	9.682	9.791	PhosphoSitePlus;EPSD	ICGC;COSMIC;GDSC;CCLE	5.915	Up-regulation
CMGC_MAPK_p38_MAPK14_ST	P17844	DDX5	Q16539	MAPK14	T446	A441T	441	Missense	distal	-5	no	9.682	10.011	PhosphoSitePlus;EPSD	ICGC;COSMIC	5.915	Up-regulation
CMGC_MAPK_p38_MAPK14_ST	P17844	DDX5	Q16539	MAPK14	S519	R516S	516	Missense	distal	-3	no	6.564	6.051	EPSD	ICGC;COSMIC	5.915	Down-regulation
CMGC_MAPK_p38_MAPK14_ST	P17844	DDX5	Q16539	MAPK14	S519	L522R	522	Missense	distal	3	no	6.564	6.517	EPSD	ICGC;COSMIC	5.915	Down-regulation
CMGC_MAPK_p38_MAPK14_ST	Q9UK80	USP21	Q16539	MAPK14	S93	L90M	90	Missense	distal	-3	no	11.055	11.363	EPSD	ICGC;COSMIC	5.915	Up-regulation
CMGC_MAPK_p38_MAPK14_ST	Q9UK80	USP21	Q16539	MAPK14	S116	G117W	117	Missense	proximal	1	no	4.757	6.583	EPSD	ICGC;COSMIC	5.915	Gain
CMGC_MAPK_p38_MAPK14_ST	Q9UK80	USP21	Q16539	MAPK14	S335	N330S	330	Missense	distal	-5	no	10.321	9.858	EPSD	ICGC;COSMIC	5.915	Down-regulation
CMGC_MAPK_p38_MAPK14_ST	Q9UK80	USP21	Q16539	MAPK14	S335	R338L	338	Missense	distal	3	no	10.321	10.368	EPSD	ICGC	5.915	Up-regulation
CMGC_MAPK_p38_MAPK14_ST	Q9UK80	USP21	Q16539	MAPK14	S335	R338C	338	Missense	distal	3	no	10.321	10.378	EPSD	ICGC;COSMIC;GDSC	5.915	Up-regulation
CMGC_MAPK_p38_MAPK14_ST	Q9UK80	USP21	Q16539	MAPK14	S368	K369N	369	Missense	proximal	1	no	5.404	6.608	EPSD	ICGC	5.915	Gain
CMGC_MAPK_p38_MAPK14_ST	Q9UK80	USP21	Q16539	MAPK14	S499	V501I	501	Missense	proximal	2	no	9.842	9.791	EPSD	ICGC;COSMIC	5.915	Down-regulation
CMGC_MAPK_p38_MAPK14_ST	P04637	TP53	Q16539	MAPK14	S15	E11K	11	Missense	distal	-4	no	5.700	5.925	EPSD;PhosphoSitePlus	ICGC;COSMIC	5.915	Gain
CMGC_MAPK_p38_MAPK14_ST	P04637	TP53	Q16539	MAPK14	S33	P34L	34	Missense	proximal	1	no	11.723	3.672	EPSD;PhosphoSitePlus	ICGC;COSMIC	5.915	Loss
CMGC_MAPK_p38_MAPK14_ST	P04637	TP53	Q16539	MAPK14	S33	S33F	33	Missense	central	0	yes	11.723	0.000	EPSD;PhosphoSitePlus	ICGC;COSMIC	5.915	Loss
CMGC_MAPK_p38_MAPK14_ST	P04637	TP53	Q16539	MAPK14	S33	N30I	30	Missense	distal	-3	no	11.723	10.799	EPSD;PhosphoSitePlus	ICGC	5.915	Down-regulation
CMGC_MAPK_p38_MAPK14_ST	P04637	TP53	Q16539	MAPK14	S46	D48G	48	Missense	proximal	2	no	11.214	11.471	PhosphoSitePlus;EPSD	ICGC;COSMIC	5.915	Up-regulation
CMGC_MAPK_p38_MAPK14_ST	P04637	TP53	Q16539	MAPK14	S46	Q52K	52	Missense	distal	6	no	11.214	11.277	PhosphoSitePlus;EPSD	ICGC	5.915	Up-regulation
CMGC_MAPK_p38_MAPK14_ST	P04637	TP53	Q16539	MAPK14	S127	T125R	125	Missense	proximal	-2	no	12.191	12.222	EPSD	ICGC;COSMIC	5.915	Up-regulation
CMGC_MAPK_p38_MAPK14_ST	P04637	TP53	Q16539	MAPK14	S127	F134C	134	Missense	distal	7	no	12.191	12.496	EPSD	ICGC;COSMIC;CCLE	5.915	Up-regulation
CMGC_MAPK_p38_MAPK14_ST	P04637	TP53	Q16539	MAPK14	S127	C124G	124	Missense	distal	-3	no	12.191	12.937	EPSD	ICGC;COSMIC	5.915	Up-regulation
CMGC_MAPK_p38_MAPK14_ST	P04637	TP53	Q16539	MAPK14	S127	C124R	124	Missense	distal	-3	no	12.191	14.387	EPSD	ICGC;COSMIC;GDSC;CCLE	5.915	Up-regulation
CMGC_MAPK_p38_MAPK14_ST	P04637	TP53	Q16539	MAPK14	S127	L130H	130	Missense	distal	3	no	12.191	12.216	EPSD	ICGC;COSMIC	5.915	Up-regulation
CMGC_MAPK_p38_MAPK14_ST	P04637	TP53	Q16539	MAPK14	S127	T125A	125	Missense	proximal	-2	no	12.191	12.248	EPSD	ICGC;COSMIC	5.915	Up-regulation
CMGC_MAPK_p38_MAPK14_ST	P04637	TP53	Q16539	MAPK14	S127	K120N	120	Missense	distal	-7	no	12.191	11.883	EPSD	ICGC;COSMIC;GDSC;CCLE	5.915	Down-regulation
CMGC_MAPK_p38_MAPK14_ST	P04637	TP53	Q16539	MAPK14	S127	N131Y	131	Missense	distal	4	no	12.191	11.661	EPSD	ICGC;COSMIC	5.915	Down-regulation
CMGC_MAPK_p38_MAPK14_ST	P04637	TP53	Q16539	MAPK14	S127	K120M	120	Missense	distal	-7	no	12.191	12.078	EPSD	ICGC;COSMIC	5.915	Down-regulation
CMGC_MAPK_p38_MAPK14_ST	P04637	TP53	Q16539	MAPK14	S127	K132M	132	Missense	distal	5	no	12.191	12.317	EPSD	ICGC;COSMIC;CCLE	5.915	Up-regulation
CMGC_MAPK_p38_MAPK14_ST	P04637	TP53	Q16539	MAPK14	S127	M133T	133	Missense	distal	6	no	12.191	12.180	EPSD	ICGC;COSMIC	5.915	Down-regulation
CMGC_MAPK_p38_MAPK14_ST	P04637	TP53	Q16539	MAPK14	S127	K120R	120	Missense	distal	-7	no	12.191	11.925	EPSD	ICGC;COSMIC	5.915	Down-regulation
CMGC_MAPK_p38_MAPK14_ST	P04637	TP53	Q16539	MAPK14	S127	C124Y	124	Missense	distal	-3	no	12.191	12.980	EPSD	ICGC;COSMIC	5.915	Up-regulation
CMGC_MAPK_p38_MAPK14_ST	P04637	TP53	Q16539	MAPK14	T150	R156L	156	Missense	distal	6	no	7.036	6.909	EPSD	ICGC;COSMIC	5.915	Down-regulation
CMGC_MAPK_p38_MAPK14_ST	P04637	TP53	Q16539	MAPK14	T150	L145Q	145	Missense	distal	-5	no	7.036	6.483	EPSD	ICGC;COSMIC	5.915	Down-regulation
CMGC_MAPK_p38_MAPK14_ST	P04637	TP53	Q16539	MAPK14	T150	P152R	152	Missense	proximal	2	no	7.036	7.267	EPSD	ICGC;COSMIC	5.915	Up-regulation
CMGC_MAPK_p38_MAPK14_ST	P04637	TP53	Q16539	MAPK14	T150	G154S	154	Missense	distal	4	no	7.036	7.268	EPSD	ICGC;COSMIC	5.915	Up-regulation
CMGC_MAPK_p38_MAPK14_ST	P04637	TP53	Q16539	MAPK14	T150	V157A	157	Missense	distal	7	no	7.036	7.145	EPSD	ICGC;COSMIC	5.915	Up-regulation
CMGC_MAPK_p38_MAPK14_ST	P04637	TP53	Q16539	MAPK14	T150	P151F	151	Missense	proximal	1	no	7.036	1.032	EPSD	ICGC;COSMIC	5.915	Loss
CMGC_MAPK_p38_MAPK14_ST	P04637	TP53	Q16539	MAPK14	T150	V147G	147	Missense	distal	-3	no	7.036	8.011	EPSD	ICGC;COSMIC;GDSC;CCLE	5.915	Up-regulation
CMGC_MAPK_p38_MAPK14_ST	P04637	TP53	Q16539	MAPK14	T211	H214D	214	Missense	distal	3	no	6.953	6.906	EPSD	ICGC;COSMIC	5.915	Down-regulation
CMGC_MAPK_p38_MAPK14_ST	P04637	TP53	Q16539	MAPK14	T211	H214Y	214	Missense	distal	3	no	6.953	6.896	EPSD	ICGC;COSMIC	5.915	Down-regulation
CMGC_MAPK_p38_MAPK14_ST	P04637	TP53	Q16539	MAPK14	T211	T211P	211	Missense	central	0	yes	6.953	0.000	EPSD	ICGC;COSMIC	5.915	Loss
CMGC_MAPK_p38_MAPK14_ST	P04637	TP53	Q16539	MAPK14	T211	F212V	212	Missense	proximal	1	no	6.953	3.679	EPSD	ICGC;COSMIC	5.915	Loss
CMGC_MAPK_p38_MAPK14_ST	P04637	TP53	Q16539	MAPK14	T211	D208V	208	Missense	distal	-3	no	6.953	6.029	EPSD	ICGC;COSMIC	5.915	Down-regulation
CMGC_MAPK_p38_MAPK14_ST	P04637	TP53	Q16539	MAPK14	T211	V217G	217	Missense	distal	6	no	6.953	7.315	EPSD	ICGC;COSMIC;CCLE	5.915	Up-regulation
CMGC_MAPK_p38_MAPK14_ST	P04637	TP53	Q16539	MAPK14	T211	S215T	215	Missense	distal	4	no	6.953	6.692	EPSD	ICGC;COSMIC	5.915	Down-regulation
CMGC_MAPK_p38_MAPK14_ST	P04637	TP53	Q16539	MAPK14	S315	T312I	312	Missense	distal	-3	no	10.517	8.763	EPSD	ICGC;COSMIC	5.915	Down-regulation
CMGC_MAPK_p38_MAPK14_ST	P04637	TP53	Q16539	MAPK14	S315	P322T	322	Missense	distal	7	no	10.517	10.418	EPSD	ICGC	5.915	Down-regulation
CMGC_MAPK_p38_MAPK14_ST	P04637	TP53	Q16539	MAPK14	S376	T377P	377	Missense	proximal	1	no	1.402	8.855	EPSD	ICGC;COSMIC	5.915	Gain
CMGC_MAPK_p38_MAPK14_ST	Q9UIG0	BAZ1B	Q16539	MAPK14	S158	G154C	154	Missense	distal	-4	no	10.399	10.863	PhosphoSitePlus	ICGC;COSMIC	5.915	Up-regulation
CMGC_MAPK_p38_MAPK14_ST	Q9UIG0	BAZ1B	Q16539	MAPK14	S158	S161N	161	Missense	distal	3	no	10.399	10.444	PhosphoSitePlus	ICGC;COSMIC	5.915	Up-regulation
CMGC_MAPK_p38_MAPK14_ST	Q9UIG0	BAZ1B	Q16539	MAPK14	S158	N165K	165	Missense	distal	7	no	10.399	10.209	PhosphoSitePlus	ICGC	5.915	Down-regulation
CMGC_MAPK_p38_MAPK14_ST	Q9UIG0	BAZ1B	Q16539	MAPK14	S161	G154C	154	Missense	distal	-7	no	5.976	5.482	EPSD	ICGC;COSMIC	5.915	Loss
CMGC_MAPK_p38_MAPK14_ST	Q9UIG0	BAZ1B	Q16539	MAPK14	S161	S161N	161	Missense	central	0	yes	5.976	0.000	EPSD	ICGC;COSMIC	5.915	Loss
CMGC_MAPK_p38_MAPK14_ST	Q9UIG0	BAZ1B	Q16539	MAPK14	S161	N165K	165	Missense	distal	4	no	5.976	6.527	EPSD	ICGC	5.915	Up-regulation
CMGC_MAPK_p38_MAPK14_ST	Q9UIG0	BAZ1B	Q16539	MAPK14	S197	R193S	193	Missense	distal	-4	no	10.765	10.754	EPSD	ICGC;COSMIC	5.915	Down-regulation
CMGC_MAPK_p38_MAPK14_ST	Q9UIG0	BAZ1B	Q16539	MAPK14	S197	R196T	196	Missense	proximal	-1	no	10.765	10.989	EPSD	ICGC	5.915	Up-regulation
CMGC_MAPK_p38_MAPK14_ST	Q9UIG0	BAZ1B	Q16539	MAPK14	T266	H259N	259	Missense	distal	-7	no	5.926	6.178	EPSD	ICGC	5.915	Up-regulation
CMGC_MAPK_p38_MAPK14_ST	Q9UIG0	BAZ1B	Q16539	MAPK14	T266	P271T	271	Missense	distal	5	no	5.926	6.210	EPSD	ICGC	5.915	Up-regulation
CMGC_MAPK_p38_MAPK14_ST	Q9UIG0	BAZ1B	Q16539	MAPK14	S312	D314E	314	Missense	proximal	2	no	11.224	11.675	EPSD	ICGC	5.915	Up-regulation
CMGC_MAPK_p38_MAPK14_ST	Q9UIG0	BAZ1B	Q16539	MAPK14	S312	P317T	317	Missense	distal	5	no	11.224	11.508	EPSD	ICGC	5.915	Up-regulation
CMGC_MAPK_p38_MAPK14_ST	Q9UIG0	BAZ1B	Q16539	MAPK14	S312	K319N	319	Missense	distal	7	no	11.224	11.414	EPSD	ICGC;COSMIC	5.915	Up-regulation
CMGC_MAPK_p38_MAPK14_ST	Q9UIG0	BAZ1B	Q16539	MAPK14	S349	S349L	349	Missense	central	0	yes	8.838	0.000	EPSD	ICGC;COSMIC	5.915	Loss
CMGC_MAPK_p38_MAPK14_ST	Q9UIG0	BAZ1B	Q16539	MAPK14	S423	P424S	424	Missense	proximal	1	no	9.033	1.749	EPSD	ICGC;COSMIC	5.915	Loss
CMGC_MAPK_p38_MAPK14_ST	Q9UIG0	BAZ1B	Q16539	MAPK14	S423	G419W	419	Missense	distal	-4	no	9.033	9.675	EPSD	ICGC;COSMIC	5.915	Up-regulation
CMGC_MAPK_p38_MAPK14_ST	Q9UIG0	BAZ1B	Q16539	MAPK14	T430	P424S	424	Missense	distal	-6	no	10.147	10.754	EPSD	ICGC;COSMIC	5.915	Up-regulation
CMGC_MAPK_p38_MAPK14_ST	Q9UIG0	BAZ1B	Q16539	MAPK14	S539	M538V	538	Missense	proximal	-1	no	6.099	6.191	EPSD	ICGC	5.915	Up-regulation
CMGC_MAPK_p38_MAPK14_ST	Q9UIG0	BAZ1B	Q16539	MAPK14	S539	K544N	544	Missense	distal	5	no	6.099	6.368	EPSD	ICGC;COSMIC	5.915	Up-regulation
CMGC_MAPK_p38_MAPK14_ST	Q9UIG0	BAZ1B	Q16539	MAPK14	S699	C695F	695	Missense	distal	-4	no	6.660	6.903	EPSD	ICGC;COSMIC	5.915	Up-regulation
CMGC_MAPK_p38_MAPK14_ST	Q9UIG0	BAZ1B	Q16539	MAPK14	T983	T982N	982	Missense	proximal	-1	no	9.006	8.961	EPSD	ICGC	5.915	Down-regulation
CMGC_MAPK_p38_MAPK14_ST	Q9UIG0	BAZ1B	Q16539	MAPK14	T983	A978S	978	Missense	distal	-5	no	9.006	8.894	EPSD	ICGC;COSMIC	5.915	Down-regulation
CMGC_MAPK_p38_MAPK14_ST	Q9UIG0	BAZ1B	Q16539	MAPK14	S1127	T1130N	1130	Missense	distal	3	no	10.837	10.868	EPSD	ICGC	5.915	Up-regulation
CMGC_MAPK_p38_MAPK14_ST	Q9UIG0	BAZ1B	Q16539	MAPK14	S1249	D1253E	1253	Missense	distal	4	no	4.882	6.551	EPSD	ICGC	5.915	Gain
CMGC_MAPK_p38_MAPK14_ST	Q9UIG0	BAZ1B	Q16539	MAPK14	S1337	R1336L	1336	Missense	proximal	-1	no	5.706	6.091	EPSD	ICGC;COSMIC	5.915	Gain
CMGC_MAPK_p38_MAPK14_ST	Q9UIG0	BAZ1B	Q16539	MAPK14	S1342	R1339W	1339	Missense	distal	-3	no	6.584	4.227	EPSD	ICGC;COSMIC	5.915	Loss
CMGC_MAPK_p38_MAPK14_ST	Q9UIG0	BAZ1B	Q16539	MAPK14	S1342	R1336Q	1336	Missense	distal	-6	no	6.584	5.914	EPSD	ICGC;COSMIC	5.915	Loss
CMGC_MAPK_p38_MAPK14_ST	Q9UIG0	BAZ1B	Q16539	MAPK14	S1342	R1336L	1336	Missense	distal	-6	no	6.584	5.470	EPSD	ICGC;COSMIC	5.915	Loss
CMGC_MAPK_p38_MAPK14_ST	Q9UIG0	BAZ1B	Q16539	MAPK14	S1342	E1344K	1344	Missense	proximal	2	no	6.584	6.270	EPSD	ICGC;COSMIC	5.915	Down-regulation
CMGC_MAPK_p38_MAPK14_ST	Q9UIG0	BAZ1B	Q16539	MAPK14	S1342	R1339Q	1339	Missense	distal	-3	no	6.584	4.805	EPSD	ICGC;GDSC	5.915	Loss
CMGC_MAPK_p38_MAPK14_ST	Q9UIG0	BAZ1B	Q16539	MAPK14	S1361	P1363T	1363	Missense	proximal	2	no	6.703	6.844	EPSD	ICGC	5.915	Up-regulation
CMGC_MAPK_p38_MAPK14_ST	Q9UIG0	BAZ1B	Q16539	MAPK14	S1361	R1365G	1365	Missense	distal	4	no	6.703	7.188	EPSD	ICGC;COSMIC	5.915	Up-regulation
CMGC_MAPK_p38_MAPK14_ST	Q15717	ELAVL1	Q16539	MAPK14	S41	V46G	46	Missense	distal	5	no	5.862	6.264	EPSD	ICGC;COSMIC	5.915	Gain
CMGC_MAPK_p38_MAPK14_ST	Q15717	ELAVL1	Q16539	MAPK14	S100	P98L	98	Missense	proximal	-2	no	6.812	5.432	EPSD	ICGC;COSMIC	5.915	Loss
CMGC_MAPK_p38_MAPK14_ST	Q15717	ELAVL1	Q16539	MAPK14	S100	R97H	97	Missense	distal	-3	no	6.812	5.058	EPSD	ICGC	5.915	Loss
CMGC_MAPK_p38_MAPK14_ST	Q15717	ELAVL1	Q16539	MAPK14	S100	Y95C	95	Missense	distal	-5	no	6.812	7.065	EPSD	ICGC	5.915	Up-regulation
CMGC_MAPK_p38_MAPK14_ST	Q15717	ELAVL1	Q16539	MAPK14	T118	G112R	112	Missense	distal	-6	no	8.701	9.075	PhosphoSitePlus	ICGC;COSMIC	5.915	Up-regulation
CMGC_MAPK_p38_MAPK14_ST	Q15717	ELAVL1	Q16539	MAPK14	T118	R115W	115	Missense	distal	-3	no	8.701	6.344	PhosphoSitePlus	ICGC;COSMIC;GDSC;CCLE	5.915	Down-regulation
CMGC_MAPK_p38_MAPK14_ST	Q15717	ELAVL1	Q16539	MAPK14	T118	T116N	116	Missense	proximal	-2	no	8.701	8.246	PhosphoSitePlus	ICGC	5.915	Down-regulation
CMGC_MAPK_p38_MAPK14_ST	Q15717	ELAVL1	Q16539	MAPK14	T118	T118N	118	Missense	central	0	yes	8.701	0.000	PhosphoSitePlus	ICGC	5.915	Loss
CMGC_MAPK_p38_MAPK14_ST	Q15717	ELAVL1	Q16539	MAPK14	T118	G112W	112	Missense	distal	-6	no	8.701	7.757	PhosphoSitePlus	ICGC;COSMIC	5.915	Down-regulation
CMGC_MAPK_p38_MAPK14_ST	Q15717	ELAVL1	Q16539	MAPK14	T118	Q119K	119	Missense	proximal	1	no	8.701	6.901	PhosphoSitePlus	ICGC;COSMIC	5.915	Down-regulation
CMGC_MAPK_p38_MAPK14_ST	Q15717	ELAVL1	Q16539	MAPK14	T118	L113H	113	Missense	distal	-5	no	8.701	8.733	PhosphoSitePlus	ICGC	5.915	Up-regulation
CMGC_MAPK_p38_MAPK14_ST	Q15717	ELAVL1	Q16539	MAPK14	S221	A215V	215	Missense	distal	-6	no	8.107	7.619	EPSD	ICGC;COSMIC	5.915	Down-regulation
CMGC_MAPK_p38_MAPK14_ST	Q15717	ELAVL1	Q16539	MAPK14	S221	S221F	221	Missense	central	0	yes	8.107	0.000	EPSD	ICGC;COSMIC	5.915	Loss
CMGC_MAPK_p38_MAPK14_ST	Q15717	ELAVL1	Q16539	MAPK14	S221	G224C	224	Missense	distal	3	no	8.107	8.150	EPSD	ICGC	5.915	Up-regulation
CMGC_MAPK_p38_MAPK14_ST	Q15717	ELAVL1	Q16539	MAPK14	S221	F218L	218	Missense	distal	-3	no	8.107	9.083	EPSD	ICGC	5.915	Up-regulation
CMGC_MAPK_p38_MAPK14_ST	Q15717	ELAVL1	Q16539	MAPK14	S221	Q216R	216	Missense	distal	-5	no	8.107	8.150	EPSD	ICGC;COSMIC	5.915	Up-regulation
CMGC_MAPK_p38_MAPK14_ST	P31645	SLC6A4	Q16539	MAPK14	S52	S52R	52	Missense	central	0	yes	9.852	0.000	EPSD	ICGC;COSMIC	5.915	Loss
CMGC_MAPK_p38_MAPK14_ST	P31645	SLC6A4	Q16539	MAPK14	S559	S555I	555	Missense	distal	-4	no	5.752	5.919	EPSD	ICGC;GDSC	5.915	Gain
CMGC_MAPK_p38_MAPK14_ST	P31645	SLC6A4	Q16539	MAPK14	S559	P561S	561	Missense	proximal	2	no	5.752	6.129	EPSD	ICGC	5.915	Gain
CMGC_MAPK_p38_MAPK14_ST	P31645	SLC6A4	Q16539	MAPK14	T613	P617Q	617	Missense	distal	4	no	8.840	8.358	EPSD	ICGC	5.915	Down-regulation
CMGC_MAPK_p38_MAPK14_ST	P31645	SLC6A4	Q16539	MAPK14	T616	P617Q	617	Missense	proximal	1	no	11.292	4.084	PhosphoSitePlus	ICGC	5.915	Loss
CMGC_MAPK_p38_MAPK14_ST	Q9NQU5	PAK6	Q16539	MAPK14	T99	L100P	100	Missense	proximal	1	no	4.796	12.846	EPSD	ICGC;COSMIC	5.915	Gain
CMGC_MAPK_p38_MAPK14_ST	Q9NQU5	PAK6	Q16539	MAPK14	S104	R101L	101	Missense	distal	-3	no	12.483	10.240	EPSD	ICGC;COSMIC	5.915	Down-regulation
CMGC_MAPK_p38_MAPK14_ST	Q9NQU5	PAK6	Q16539	MAPK14	S104	L100P	100	Missense	distal	-4	no	12.483	11.971	EPSD	ICGC;COSMIC	5.915	Down-regulation
CMGC_MAPK_p38_MAPK14_ST	Q9NQU5	PAK6	Q16539	MAPK14	S104	L100M	100	Missense	distal	-4	no	12.483	11.955	EPSD	ICGC;COSMIC	5.915	Down-regulation
CMGC_MAPK_p38_MAPK14_ST	Q9NQU5	PAK6	Q16539	MAPK14	S132	D125Y	125	Missense	distal	-7	no	11.251	11.121	EPSD	ICGC;CCLE	5.915	Down-regulation
CMGC_MAPK_p38_MAPK14_ST	Q9NQU5	PAK6	Q16539	MAPK14	S165	E162V	162	Missense	distal	-3	no	8.810	7.680	PhosphoSitePlus	ICGC;COSMIC	5.915	Down-regulation
CMGC_MAPK_p38_MAPK14_ST	Q9NQU5	PAK6	Q16539	MAPK14	S165	P163Q	163	Missense	proximal	-2	no	8.810	7.795	PhosphoSitePlus	ICGC;COSMIC	5.915	Down-regulation
CMGC_MAPK_p38_MAPK14_ST	Q9NQU5	PAK6	Q16539	MAPK14	S165	R167L	167	Missense	proximal	2	no	8.810	8.466	PhosphoSitePlus	ICGC;COSMIC	5.915	Down-regulation
CMGC_MAPK_p38_MAPK14_ST	Q9NQU5	PAK6	Q16539	MAPK14	S202	P209T	209	Missense	distal	7	no	11.366	11.267	EPSD	ICGC;COSMIC	5.915	Down-regulation
CMGC_MAPK_p38_MAPK14_ST	Q9NQU5	PAK6	Q16539	MAPK14	S202	P209S	209	Missense	distal	7	no	11.366	11.588	EPSD	ICGC	5.915	Up-regulation
CMGC_MAPK_p38_MAPK14_ST	Q9NQU5	PAK6	Q16539	MAPK14	S207	P209T	209	Missense	proximal	2	no	9.271	9.413	EPSD	ICGC;COSMIC	5.915	Up-regulation
CMGC_MAPK_p38_MAPK14_ST	Q9NQU5	PAK6	Q16539	MAPK14	S207	P209S	209	Missense	proximal	2	no	9.271	9.648	EPSD	ICGC	5.915	Up-regulation
CMGC_MAPK_p38_MAPK14_ST	Q9NQU5	PAK6	Q16539	MAPK14	S207	R214M	214	Missense	distal	7	no	9.271	9.107	EPSD	ICGC	5.915	Down-regulation
CMGC_MAPK_p38_MAPK14_ST	Q9NQU5	PAK6	Q16539	MAPK14	S246	G243W	243	Missense	distal	-3	no	15.109	14.202	EPSD	ICGC;COSMIC	5.915	Down-regulation
CMGC_MAPK_p38_MAPK14_ST	Q9NQU5	PAK6	Q16539	MAPK14	S246	R252L	252	Missense	distal	6	no	15.109	14.982	EPSD	ICGC;COSMIC	5.915	Down-regulation
CMGC_MAPK_p38_MAPK14_ST	Q9NQU5	PAK6	Q16539	MAPK14	S246	P249T	249	Missense	distal	3	no	15.109	15.083	EPSD	ICGC;COSMIC	5.915	Down-regulation
CMGC_MAPK_p38_MAPK14_ST	Q9NQU5	PAK6	Q16539	MAPK14	S248	G243W	243	Missense	distal	-5	no	11.306	11.889	EPSD	ICGC;COSMIC	5.915	Up-regulation
CMGC_MAPK_p38_MAPK14_ST	Q9NQU5	PAK6	Q16539	MAPK14	S248	R252L	252	Missense	distal	4	no	11.306	10.944	EPSD	ICGC;COSMIC	5.915	Down-regulation
CMGC_MAPK_p38_MAPK14_ST	Q9NQU5	PAK6	Q16539	MAPK14	S248	P249T	249	Missense	proximal	1	no	11.306	3.853	EPSD	ICGC;COSMIC	5.915	Loss
CMGC_MAPK_p38_MAPK14_ST	Q9NQU5	PAK6	Q16539	MAPK14	T317	P314L	314	Missense	distal	-3	no	6.360	5.392	EPSD	ICGC;COSMIC	5.915	Loss
CMGC_MAPK_p38_MAPK14_ST	Q9NQU5	PAK6	Q16539	MAPK14	S319	P314L	314	Missense	distal	-5	no	10.984	11.265	EPSD	ICGC;COSMIC	5.915	Up-regulation
CMGC_MAPK_p38_MAPK14_ST	Q9NQU5	PAK6	Q16539	MAPK14	S328	L333F	333	Missense	distal	5	no	10.654	10.160	EPSD	ICGC;COSMIC	5.915	Down-regulation
CMGC_MAPK_p38_MAPK14_ST	Q9NQU5	PAK6	Q16539	MAPK14	S347	R345L	345	Missense	proximal	-2	no	11.402	10.710	EPSD	ICGC;COSMIC	5.915	Down-regulation
CMGC_MAPK_p38_MAPK14_ST	Q9NQU5	PAK6	Q16539	MAPK14	S351	A357T	357	Missense	distal	6	no	8.820	8.802	EPSD	ICGC;COSMIC;GDSC	5.915	Down-regulation
CMGC_MAPK_p38_MAPK14_ST	Q9NQU5	PAK6	Q16539	MAPK14	S351	R345L	345	Missense	distal	-6	no	8.820	7.706	EPSD	ICGC;COSMIC	5.915	Down-regulation
CMGC_MAPK_p38_MAPK14_ST	Q9NQU5	PAK6	Q16539	MAPK14	S351	G350V	350	Missense	proximal	-1	no	8.820	8.822	EPSD	ICGC;COSMIC	5.915	Up-regulation
CMGC_MAPK_p38_MAPK14_ST	Q9NQU5	PAK6	Q16539	MAPK14	T354	G350V	350	Missense	distal	-4	no	6.255	6.580	EPSD	ICGC;COSMIC	5.915	Up-regulation
CMGC_MAPK_p38_MAPK14_ST	P00533	EGFR	Q16539	MAPK14	S511	V505L	505	Missense	distal	-6	no	8.922	8.733	EPSD	ICGC;COSMIC	5.915	Down-regulation
CMGC_MAPK_p38_MAPK14_ST	P00533	EGFR	Q16539	MAPK14	S511	C510R	510	Missense	proximal	-1	no	8.922	8.659	EPSD	ICGC;COSMIC	5.915	Down-regulation
CMGC_MAPK_p38_MAPK14_ST	P00533	EGFR	Q16539	MAPK14	T693	A698T	698	Missense	distal	5	no	14.877	15.349	EPSD;PhosphoSitePlus	ICGC;COSMIC	5.915	Up-regulation
CMGC_MAPK_p38_MAPK14_ST	P00533	EGFR	Q16539	MAPK14	S925	E922A	922	Missense	distal	-3	no	6.152	6.522	EPSD	ICGC;COSMIC	5.915	Up-regulation
CMGC_MAPK_p38_MAPK14_ST	P00533	EGFR	Q16539	MAPK14	S925	R932L	932	Missense	distal	7	no	6.152	5.733	EPSD	ICGC	5.915	Loss
CMGC_MAPK_p38_MAPK14_ST	P00533	EGFR	Q16539	MAPK14	S925	R932H	932	Missense	distal	7	no	6.152	5.618	EPSD	ICGC;COSMIC	5.915	Loss
CMGC_MAPK_p38_MAPK14_ST	P00533	EGFR	Q16539	MAPK14	S991	R986Q	986	Missense	distal	-5	no	10.756	10.713	EPSD	ICGC;COSMIC	5.915	Down-regulation
CMGC_MAPK_p38_MAPK14_ST	P00533	EGFR	Q16539	MAPK14	S991	S991R	991	Missense	central	0	yes	10.756	0.000	EPSD	ICGC;COSMIC	5.915	Loss
CMGC_MAPK_p38_MAPK14_ST	P00533	EGFR	Q16539	MAPK14	S991	L989I	989	Missense	proximal	-2	no	10.756	11.318	EPSD	ICGC;COSMIC	5.915	Up-regulation
CMGC_MAPK_p38_MAPK14_ST	P00533	EGFR	Q16539	MAPK14	S1130	P1136H	1136	Missense	distal	6	no	6.415	6.295	EPSD	ICGC	5.915	Down-regulation
CMGC_MAPK_p38_MAPK14_ST	P00533	EGFR	Q16539	MAPK14	S1153	A1155T	1155	Missense	proximal	2	no	7.391	7.420	EPSD	ICGC	5.915	Up-regulation
CMGC_MAPK_p38_MAPK14_ST	P00533	EGFR	Q16539	MAPK14	S1153	H1156N	1156	Missense	distal	3	no	7.391	7.338	EPSD	ICGC;COSMIC	5.915	Down-regulation
CMGC_MAPK_p38_MAPK14_ST	P00533	EGFR	Q16539	MAPK14	S1153	S1153I	1153	Missense	central	0	yes	7.391	0.000	EPSD	ICGC;COSMIC	5.915	Loss
CMGC_MAPK_p38_MAPK14_ST	P00533	EGFR	Q16539	MAPK14	S1153	F1151I	1151	Missense	proximal	-2	no	7.391	7.786	EPSD	ICGC	5.915	Up-regulation
CMGC_MAPK_p38_MAPK14_ST	P00533	EGFR	Q16539	MAPK14	S1153	S1153N	1153	Missense	central	0	yes	7.391	0.000	EPSD	ICGC;COSMIC	5.915	Loss
CMGC_MAPK_p38_MAPK14_ST	Q06413	MEF2C	Q16539	MAPK14	S82	E86K	86	Missense	distal	4	no	7.468	7.002	EPSD	ICGC;COSMIC	5.915	Down-regulation
CMGC_MAPK_p38_MAPK14_ST	Q06413	MEF2C	Q16539	MAPK14	S82	V85E	85	Missense	distal	3	no	7.468	7.422	EPSD	ICGC;COSMIC	5.915	Down-regulation
CMGC_MAPK_p38_MAPK14_ST	Q06413	MEF2C	Q16539	MAPK14	S82	H76N	76	Missense	distal	-6	no	7.468	8.114	EPSD	ICGC;COSMIC	5.915	Up-regulation
CMGC_MAPK_p38_MAPK14_ST	Q06413	MEF2C	Q16539	MAPK14	S82	T80K	80	Missense	proximal	-2	no	7.468	6.896	EPSD	ICGC	5.915	Down-regulation
CMGC_MAPK_p38_MAPK14_ST	Q06413	MEF2C	Q16539	MAPK14	S82	D83V	83	Missense	proximal	1	no	7.468	5.621	EPSD	ICGC	5.915	Loss
CMGC_MAPK_p38_MAPK14_ST	Q06413	MEF2C	Q16539	MAPK14	S82	E77V	77	Missense	distal	-5	no	7.468	8.322	EPSD	ICGC;COSMIC	5.915	Up-regulation
CMGC_MAPK_p38_MAPK14_ST	Q06413	MEF2C	Q16539	MAPK14	S98	D105N	105	Missense	distal	7	no	10.232	9.911	EPSD	ICGC;COSMIC	5.915	Down-regulation
CMGC_MAPK_p38_MAPK14_ST	Q06413	MEF2C	Q16539	MAPK14	S98	D104E	104	Missense	distal	6	no	10.232	10.333	EPSD	ICGC;COSMIC	5.915	Up-regulation
CMGC_MAPK_p38_MAPK14_ST	Q06413	MEF2C	Q16539	MAPK14	S110	D105N	105	Missense	distal	-5	no	11.217	11.057	EPSD	ICGC;COSMIC	5.915	Down-regulation
CMGC_MAPK_p38_MAPK14_ST	Q06413	MEF2C	Q16539	MAPK14	S110	G108C	108	Missense	proximal	-2	no	11.217	10.531	EPSD	ICGC;COSMIC	5.915	Down-regulation
CMGC_MAPK_p38_MAPK14_ST	Q06413	MEF2C	Q16539	MAPK14	S110	D104E	104	Missense	distal	-6	no	11.217	11.795	EPSD	ICGC;COSMIC	5.915	Up-regulation
CMGC_MAPK_p38_MAPK14_ST	Q06413	MEF2C	Q16539	MAPK14	S110	Y117H	117	Missense	distal	7	no	11.217	10.675	EPSD	ICGC	5.915	Down-regulation
CMGC_MAPK_p38_MAPK14_ST	Q06413	MEF2C	Q16539	MAPK14	S110	S110I	110	Missense	central	0	yes	11.217	0.000	EPSD	ICGC;COSMIC	5.915	Loss
CMGC_MAPK_p38_MAPK14_ST	Q06413	MEF2C	Q16539	MAPK14	S183	H188R	188	Missense	distal	5	no	8.120	8.815	EPSD	ICGC;COSMIC	5.915	Up-regulation
CMGC_MAPK_p38_MAPK14_ST	Q06413	MEF2C	Q16539	MAPK14	S183	P190L	190	Missense	distal	7	no	8.120	7.957	EPSD	ICGC;COSMIC	5.915	Down-regulation
CMGC_MAPK_p38_MAPK14_ST	Q06413	MEF2C	Q16539	MAPK14	S183	R189Q	189	Missense	distal	6	no	8.120	8.132	EPSD	ICGC;COSMIC	5.915	Up-regulation
CMGC_MAPK_p38_MAPK14_ST	Q06413	MEF2C	Q16539	MAPK14	S183	P190S	190	Missense	distal	7	no	8.120	8.342	EPSD	ICGC;COSMIC	5.915	Up-regulation
CMGC_MAPK_p38_MAPK14_ST	Q06413	MEF2C	Q16539	MAPK14	S183	S183F	183	Missense	central	0	yes	8.120	0.000	EPSD	ICGC;COSMIC	5.915	Loss
CMGC_MAPK_p38_MAPK14_ST	Q06413	MEF2C	Q16539	MAPK14	S222	R220Q	220	Missense	proximal	-2	no	11.367	11.041	EPSD	ICGC;COSMIC	5.915	Down-regulation
CMGC_MAPK_p38_MAPK14_ST	Q06413	MEF2C	Q16539	MAPK14	S222	G215W	215	Missense	distal	-7	no	11.367	10.527	EPSD	ICGC;COSMIC	5.915	Down-regulation
CMGC_MAPK_p38_MAPK14_ST	Q06413	MEF2C	Q16539	MAPK14	S222	P219S	219	Missense	distal	-3	no	11.367	12.131	EPSD	ICGC;COSMIC	5.915	Up-regulation
CMGC_MAPK_p38_MAPK14_ST	Q06413	MEF2C	Q16539	MAPK14	S222	V227A	227	Missense	distal	5	no	11.367	11.386	EPSD	ICGC;COSMIC	5.915	Up-regulation
CMGC_MAPK_p38_MAPK14_ST	Q06413	MEF2C	Q16539	MAPK14	S228	G230S	230	Missense	proximal	2	no	9.897	10.126	EPSD	ICGC;COSMIC	5.915	Up-regulation
CMGC_MAPK_p38_MAPK14_ST	Q06413	MEF2C	Q16539	MAPK14	S228	V227A	227	Missense	proximal	-1	no	9.897	9.741	EPSD	ICGC;COSMIC	5.915	Down-regulation
CMGC_MAPK_p38_MAPK14_ST	Q06413	MEF2C	Q16539	MAPK14	S240	L246V	246	Missense	distal	6	no	10.836	10.722	EPSD	ICGC;COSMIC	5.915	Down-regulation
CMGC_MAPK_p38_MAPK14_ST	Q06413	MEF2C	Q16539	MAPK14	T293	A288S	288	Missense	distal	-5	no	11.739	11.627	EPSD;PhosphoSitePlus	ICGC;COSMIC	5.915	Down-regulation
CMGC_MAPK_p38_MAPK14_ST	Q06413	MEF2C	Q16539	MAPK14	T293	S297F	297	Missense	distal	4	no	11.739	10.164	EPSD;PhosphoSitePlus	ICGC;COSMIC	5.915	Down-regulation
CMGC_MAPK_p38_MAPK14_ST	Q06413	MEF2C	Q16539	MAPK14	T300	S297F	297	Missense	distal	-3	no	9.337	6.630	EPSD;PhosphoSitePlus	ICGC;COSMIC	5.915	Down-regulation
CMGC_MAPK_p38_MAPK14_ST	Q06413	MEF2C	Q16539	MAPK14	S387	L380F	380	Missense	distal	-7	no	5.932	5.466	PhosphoSitePlus;EPSD	ICGC;COSMIC	5.915	Loss
CMGC_MAPK_p38_MAPK14_ST	Q06413	MEF2C	Q16539	MAPK14	S396	P397R	397	Missense	proximal	1	no	11.143	3.207	EPSD	ICGC;COSMIC	5.915	Loss
CMGC_MAPK_p38_MAPK14_ST	Q06413	MEF2C	Q16539	MAPK14	S396	P397T	397	Missense	proximal	1	no	11.143	3.689	EPSD	ICGC;COSMIC	5.915	Loss
CMGC_MAPK_p38_MAPK14_ST	Q06413	MEF2C	Q16539	MAPK14	T404	P397R	397	Missense	distal	-7	no	8.260	8.179	EPSD	ICGC;COSMIC	5.915	Down-regulation
CMGC_MAPK_p38_MAPK14_ST	Q06413	MEF2C	Q16539	MAPK14	T404	T404M	404	Missense	central	0	yes	8.260	0.000	EPSD	ICGC;COSMIC	5.915	Loss
CMGC_MAPK_p38_MAPK14_ST	Q06413	MEF2C	Q16539	MAPK14	T404	T404K	404	Missense	central	0	yes	8.260	0.000	EPSD	ICGC	5.915	Loss
CMGC_MAPK_p38_MAPK14_ST	Q06413	MEF2C	Q16539	MAPK14	T404	P397T	397	Missense	distal	-7	no	8.260	8.278	EPSD	ICGC;COSMIC	5.915	Up-regulation
CMGC_MAPK_p38_MAPK14_ST	Q06413	MEF2C	Q16539	MAPK14	S419	S426R	426	Missense	distal	7	no	14.517	14.551	EPSD	ICGC	5.915	Up-regulation
CMGC_MAPK_p38_MAPK14_ST	P42574	CASP3	Q16539	MAPK14	S150	R147H	147	Missense	distal	-3	no	7.178	5.424	PhosphoSitePlus	ICGC;COSMIC	5.915	Loss
CMGC_MAPK_p38_MAPK14_ST	P42574	CASP3	Q16539	MAPK14	S150	L151I	151	Missense	proximal	1	no	7.178	7.550	PhosphoSitePlus	ICGC	5.915	Up-regulation
CMGC_MAPK_p38_MAPK14_ST	P06702	S100A9	Q16539	MAPK14	T113	G112D	112	Missense	proximal	-1	no	12.598	12.642	PhosphoSitePlus	ICGC;COSMIC	5.915	Up-regulation
CMGC_MAPK_p38_MAPK14_ST	P06702	S100A9	Q16539	MAPK14	T113	G110R	110	Missense	distal	-3	no	12.598	14.048	PhosphoSitePlus	ICGC;COSMIC;CCLE	5.915	Up-regulation
CMGC_MAPK_p38_MAPK14_ST	Q8NHW3	MAFA	Q16539	MAPK14	T53	S56N	56	Missense	distal	3	no	9.989	10.035	EPSD	ICGC;COSMIC	5.915	Up-regulation
CMGC_MAPK_p38_MAPK14_ST	Q8NHW3	MAFA	Q16539	MAPK14	T53	S52L	52	Missense	proximal	-1	no	9.989	10.267	EPSD	ICGC;COSMIC	5.915	Up-regulation
CMGC_MAPK_p38_MAPK14_ST	Q8NHW3	MAFA	Q16539	MAPK14	T57	S56N	56	Missense	proximal	-1	no	9.694	9.766	PhosphoSitePlus;EPSD	ICGC;COSMIC	5.915	Up-regulation
CMGC_MAPK_p38_MAPK14_ST	Q8NHW3	MAFA	Q16539	MAPK14	T57	S52L	52	Missense	distal	-5	no	9.694	10.423	PhosphoSitePlus;EPSD	ICGC;COSMIC	5.915	Up-regulation
CMGC_MAPK_p38_MAPK14_ST	Q8NHW3	MAFA	Q16539	MAPK14	S325	G328R	328	Missense	distal	3	no	6.772	6.758	EPSD	ICGC;COSMIC;GDSC;CCLE	5.915	Down-regulation
CMGC_MAPK_p38_MAPK14_ST	Q14934	NFATC4	Q16539	MAPK14	S73	R77H	77	Missense	distal	4	no	10.251	9.858	EPSD	ICGC;COSMIC	5.915	Down-regulation
CMGC_MAPK_p38_MAPK14_ST	Q14934	NFATC4	Q16539	MAPK14	S73	P74L	74	Missense	proximal	1	no	10.251	2.200	EPSD	ICGC;COSMIC	5.915	Loss
CMGC_MAPK_p38_MAPK14_ST	Q14934	NFATC4	Q16539	MAPK14	S311	P314L	314	Missense	distal	3	no	9.701	9.735	EPSD	ICGC;COSMIC	5.915	Up-regulation
CMGC_MAPK_p38_MAPK14_ST	Q14934	NFATC4	Q16539	MAPK14	S395	P396S	396	Missense	proximal	1	no	11.551	4.267	EPSD	ICGC;COSMIC	5.915	Loss
CMGC_MAPK_p38_MAPK14_ST	Q14934	NFATC4	Q16539	MAPK14	S592	V598F	598	Missense	distal	6	no	12.002	11.886	EPSD	ICGC;COSMIC	5.915	Down-regulation
CMGC_MAPK_p38_MAPK14_ST	Q14934	NFATC4	Q16539	MAPK14	S592	V588A	588	Missense	distal	-4	no	12.002	11.720	EPSD	ICGC;COSMIC	5.915	Down-regulation
CMGC_MAPK_p38_MAPK14_ST	Q14934	NFATC4	Q16539	MAPK14	S716	F715C	715	Missense	proximal	-1	no	11.261	11.174	EPSD	ICGC;COSMIC	5.915	Down-regulation
CMGC_MAPK_p38_MAPK14_ST	Q14934	NFATC4	Q16539	MAPK14	S819	P820S	820	Missense	proximal	1	no	11.591	4.307	EPSD	ICGC;COSMIC	5.915	Loss
CMGC_MAPK_p38_MAPK14_ST	Q9BR76	CORO1B	Q16539	MAPK14	T439	D437G	437	Missense	proximal	-2	no	9.985	10.736	EPSD	ICGC;COSMIC	5.915	Up-regulation
CMGC_MAPK_p38_MAPK14_ST	Q9BR76	CORO1B	Q16539	MAPK14	T439	A445T	445	Missense	distal	6	no	9.985	9.968	EPSD	ICGC;COSMIC	5.915	Down-regulation
CMGC_MAPK_p38_MAPK14_ST	Q9BR76	CORO1B	Q16539	MAPK14	S441	D437G	437	Missense	distal	-4	no	6.942	6.447	EPSD	ICGC;COSMIC	5.915	Down-regulation
CMGC_MAPK_p38_MAPK14_ST	Q9BR76	CORO1B	Q16539	MAPK14	S441	G448R	448	Missense	distal	7	no	6.942	7.120	EPSD	ICGC;COSMIC	5.915	Up-regulation
CMGC_MAPK_p38_MAPK14_ST	Q9BR76	CORO1B	Q16539	MAPK14	S441	A445T	445	Missense	distal	4	no	6.942	6.987	EPSD	ICGC;COSMIC	5.915	Up-regulation
CMGC_MAPK_p38_MAPK14_ST	O43524	FOXO3	Q16539	MAPK14	S7	P10T	10	Missense	distal	3	no	10.158	10.131	PhosphoSitePlus;EPSD	ICGC;COSMIC	5.915	Down-regulation
CMGC_MAPK_p38_MAPK14_ST	O43524	FOXO3	Q16539	MAPK14	S12	P10T	10	Missense	proximal	-2	no	13.512	12.792	EPSD;PhosphoSitePlus	ICGC;COSMIC	5.915	Down-regulation
CMGC_MAPK_p38_MAPK14_ST	O43524	FOXO3	Q16539	MAPK14	T32	S26C	26	Missense	distal	-6	no	7.301	6.008	EPSD	ICGC;COSMIC	5.915	Down-regulation
CMGC_MAPK_p38_MAPK14_ST	O43524	FOXO3	Q16539	MAPK14	S55	D62N	62	Missense	distal	7	no	6.289	5.967	EPSD	ICGC	5.915	Down-regulation
CMGC_MAPK_p38_MAPK14_ST	O43524	FOXO3	Q16539	MAPK14	S284	S286T	286	Missense	proximal	2	no	9.609	9.373	EPSD	ICGC	5.915	Down-regulation
CMGC_MAPK_p38_MAPK14_ST	O43524	FOXO3	Q16539	MAPK14	S284	S286F	286	Missense	proximal	2	no	9.609	8.943	EPSD	ICGC	5.915	Down-regulation
CMGC_MAPK_p38_MAPK14_ST	O43524	FOXO3	Q16539	MAPK14	S325	S330N	330	Missense	distal	5	no	12.190	11.854	EPSD	ICGC;COSMIC	5.915	Down-regulation
CMGC_MAPK_p38_MAPK14_ST	O43524	FOXO3	Q16539	MAPK14	S344	D339N	339	Missense	distal	-5	no	12.103	11.943	EPSD;PhosphoSitePlus	ICGC	5.915	Down-regulation
CMGC_MAPK_p38_MAPK14_ST	O43524	FOXO3	Q16539	MAPK14	S344	D339V	339	Missense	distal	-5	no	12.103	12.083	EPSD;PhosphoSitePlus	ICGC;COSMIC	5.915	Down-regulation
CMGC_MAPK_p38_MAPK14_ST	O43524	FOXO3	Q16539	MAPK14	S402	S399F	399	Missense	distal	-3	no	11.728	9.021	EPSD	ICGC	5.915	Down-regulation
CMGC_MAPK_p38_MAPK14_ST	O43524	FOXO3	Q16539	MAPK14	S425	G424S	424	Missense	proximal	-1	no	11.529	11.316	EPSD;PhosphoSitePlus	ICGC;COSMIC	5.915	Down-regulation
CMGC_MAPK_p38_MAPK14_ST	O43524	FOXO3	Q16539	MAPK14	S425	G420S	420	Missense	distal	-5	no	11.529	11.147	EPSD;PhosphoSitePlus	ICGC;COSMIC	5.915	Down-regulation
CMGC_MAPK_p38_MAPK14_ST	O43524	FOXO3	Q16539	MAPK14	S425	S429Y	429	Missense	distal	4	no	11.529	10.481	EPSD;PhosphoSitePlus	ICGC;COSMIC	5.915	Down-regulation
CMGC_MAPK_p38_MAPK14_ST	O43524	FOXO3	Q16539	MAPK14	S446	N441K	441	Missense	distal	-5	no	7.519	7.139	EPSD	ICGC	5.915	Down-regulation
CMGC_MAPK_p38_MAPK14_ST	O43524	FOXO3	Q16539	MAPK14	S446	S442F	442	Missense	distal	-4	no	7.519	8.224	EPSD	ICGC;COSMIC	5.915	Up-regulation
CMGC_MAPK_p38_MAPK14_ST	O43524	FOXO3	Q16539	MAPK14	S669	S669I	669	Missense	central	0	yes	8.191	0.000	EPSD	ICGC;COSMIC	5.915	Loss
CMGC_MAPK_p38_MAPK14_ST	P42566	EPS15	Q16539	MAPK14	S108	P109S	109	Missense	proximal	1	no	12.236	4.952	EPSD	ICGC	5.915	Loss
CMGC_MAPK_p38_MAPK14_ST	P42566	EPS15	Q16539	MAPK14	S108	D105Y	105	Missense	distal	-3	no	12.236	12.330	EPSD	ICGC;COSMIC	5.915	Up-regulation
CMGC_MAPK_p38_MAPK14_ST	P42566	EPS15	Q16539	MAPK14	S140	L146M	146	Missense	distal	6	no	10.755	10.931	EPSD	ICGC	5.915	Up-regulation
CMGC_MAPK_p38_MAPK14_ST	P42566	EPS15	Q16539	MAPK14	S221	T217M	217	Missense	distal	-4	no	11.326	11.120	EPSD	ICGC;COSMIC	5.915	Down-regulation
CMGC_MAPK_p38_MAPK14_ST	P42566	EPS15	Q16539	MAPK14	S221	W218G	218	Missense	distal	-3	no	11.326	12.233	EPSD	ICGC;COSMIC	5.915	Up-regulation
CMGC_MAPK_p38_MAPK14_ST	P42566	EPS15	Q16539	MAPK14	T304	H301L	301	Missense	distal	-3	no	10.225	9.735	EPSD	ICGC;COSMIC	5.915	Down-regulation
CMGC_MAPK_p38_MAPK14_ST	P42566	EPS15	Q16539	MAPK14	S324	P325H	325	Missense	proximal	1	no	8.909	-4.744	EPSD	ICGC	5.915	Loss
CMGC_MAPK_p38_MAPK14_ST	P42566	EPS15	Q16539	MAPK14	S330	P325H	325	Missense	distal	-5	no	7.637	7.951	EPSD	ICGC	5.915	Up-regulation
CMGC_MAPK_p38_MAPK14_ST	P42566	EPS15	Q16539	MAPK14	S330	K333N	333	Missense	distal	3	no	7.637	7.638	EPSD	ICGC;COSMIC	5.915	Up-regulation
CMGC_MAPK_p38_MAPK14_ST	P42566	EPS15	Q16539	MAPK14	S330	K333R	333	Missense	distal	3	no	7.637	7.621	EPSD	ICGC;COSMIC	5.915	Down-regulation
CMGC_MAPK_p38_MAPK14_ST	P42566	EPS15	Q16539	MAPK14	T337	K333N	333	Missense	distal	-4	no	5.779	5.925	EPSD	ICGC;COSMIC	5.915	Gain
CMGC_MAPK_p38_MAPK14_ST	O60381	HBP1	Q16539	MAPK14	S157	R151C	151	Missense	distal	-6	no	8.293	7.107	EPSD	ICGC;COSMIC;GDSC	5.915	Down-regulation
CMGC_MAPK_p38_MAPK14_ST	O60381	HBP1	Q16539	MAPK14	S157	R151S	151	Missense	distal	-6	no	8.293	8.400	EPSD	ICGC;COSMIC	5.915	Up-regulation
CMGC_MAPK_p38_MAPK14_ST	O60381	HBP1	Q16539	MAPK14	S402	G401C	401	Missense	proximal	-1	no	9.658	9.601	PhosphoSitePlus	ICGC	5.915	Down-regulation
CMGC_MAPK_p38_MAPK14_ST	O60381	HBP1	Q16539	MAPK14	S405	G401C	401	Missense	distal	-4	no	5.663	6.127	EPSD	ICGC	5.915	Gain
CMGC_MAPK_p38_MAPK14_ST	O60381	HBP1	Q16539	MAPK14	S430	R436G	436	Missense	distal	6	no	10.635	10.756	EPSD	ICGC;COSMIC	5.915	Up-regulation
CMGC_MAPK_p38_MAPK14_ST	O60381	HBP1	Q16539	MAPK14	S430	R436I	436	Missense	distal	6	no	10.635	10.425	EPSD	ICGC;COSMIC	5.915	Down-regulation
CMGC_MAPK_p38_MAPK14_ST	Q8IW41	MAPKAPK5	Q16539	MAPK14	S212	Y218C	218	Missense	distal	6	no	11.797	11.504	EPSD	ICGC	5.915	Down-regulation
CMGC_MAPK_p38_MAPK14_ST	Q8IW41	MAPKAPK5	Q16539	MAPK14	S212	G207V	207	Missense	distal	-5	no	11.797	12.019	EPSD	ICGC	5.915	Up-regulation
CMGC_MAPK_p38_MAPK14_ST	Q8IW41	MAPKAPK5	Q16539	MAPK14	T214	Y218C	218	Missense	distal	4	no	9.025	8.921	EPSD	ICGC	5.915	Down-regulation
CMGC_MAPK_p38_MAPK14_ST	Q8IW41	MAPKAPK5	Q16539	MAPK14	T214	G207V	207	Missense	distal	-7	no	9.025	8.388	EPSD	ICGC	5.915	Down-regulation
CMGC_MAPK_p38_MAPK14_ST	Q8IW41	MAPKAPK5	Q16539	MAPK14	T217	Y218C	218	Missense	proximal	1	no	6.492	2.043	EPSD	ICGC	5.915	Loss
CMGC_MAPK_p38_MAPK14_ST	P42677	RPS27	Q16539	MAPK14	S11	P10S	10	Missense	proximal	-1	no	11.304	11.211	EPSD	ICGC;COSMIC	5.915	Down-regulation
CMGC_MAPK_p38_MAPK14_ST	P42677	RPS27	Q16539	MAPK14	S11	L8I	8	Missense	distal	-3	no	11.304	10.963	EPSD	ICGC;COSMIC	5.915	Down-regulation
CMGC_MAPK_p38_MAPK14_ST	P42677	RPS27	Q16539	MAPK14	S27	K22R	22	Missense	distal	-5	no	10.240	10.375	PhosphoSitePlus	ICGC;COSMIC	5.915	Up-regulation
CMGC_MAPK_p38_MAPK14_ST	P42677	RPS27	Q16539	MAPK14	S27	S30Y	30	Missense	distal	3	no	10.240	10.281	PhosphoSitePlus	ICGC;COSMIC	5.915	Up-regulation
CMGC_MAPK_p38_MAPK14_ST	P17302	GJA1	Q16539	MAPK14	S255	A249V	249	Missense	distal	-6	no	9.570	9.082	EPSD	ICGC;COSMIC;GDSC;CCLE	5.915	Down-regulation
CMGC_MAPK_p38_MAPK14_ST	P17302	GJA1	Q16539	MAPK14	S255	L254P	254	Missense	proximal	-1	no	9.570	9.384	EPSD	ICGC	5.915	Down-regulation
CMGC_MAPK_p38_MAPK14_ST	P17302	GJA1	Q16539	MAPK14	S279	G285V	285	Missense	distal	6	no	14.969	14.607	PhosphoSitePlus;EPSD	ICGC;COSMIC	5.915	Down-regulation
CMGC_MAPK_p38_MAPK14_ST	P17302	GJA1	Q16539	MAPK14	S279	P284L	284	Missense	distal	5	no	14.969	14.472	PhosphoSitePlus;EPSD	ICGC	5.915	Down-regulation
CMGC_MAPK_p38_MAPK14_ST	P17302	GJA1	Q16539	MAPK14	S282	P284L	284	Missense	proximal	2	no	13.285	13.172	EPSD;PhosphoSitePlus	ICGC	5.915	Down-regulation
CMGC_MAPK_p38_MAPK14_ST	P17302	GJA1	Q16539	MAPK14	S282	V289L	289	Missense	distal	7	no	13.285	12.986	EPSD;PhosphoSitePlus	ICGC;COSMIC	5.915	Down-regulation
CMGC_MAPK_p38_MAPK14_ST	P17302	GJA1	Q16539	MAPK14	S364	R362Q	362	Missense	proximal	-2	no	6.602	6.275	EPSD	ICGC;COSMIC;GDSC	5.915	Down-regulation
CMGC_MAPK_p38_MAPK14_ST	P17302	GJA1	Q16539	MAPK14	S364	D360E	360	Missense	distal	-4	no	6.602	5.810	EPSD	ICGC;COSMIC	5.915	Loss
CMGC_MAPK_p38_MAPK14_ST	P17302	GJA1	Q16539	MAPK14	S364	R370H	370	Missense	distal	6	no	6.602	6.495	EPSD	ICGC;GDSC;CCLE	5.915	Down-regulation
CMGC_MAPK_p38_MAPK14_ST	P17302	GJA1	Q16539	MAPK14	S368	R362Q	362	Missense	distal	-6	no	7.255	6.585	EPSD	ICGC;COSMIC;GDSC	5.915	Down-regulation
CMGC_MAPK_p38_MAPK14_ST	P17302	GJA1	Q16539	MAPK14	S368	R370H	370	Missense	proximal	2	no	7.255	6.872	EPSD	ICGC;GDSC;CCLE	5.915	Down-regulation
CMGC_MAPK_p38_MAPK14_ST	P17302	GJA1	Q16539	MAPK14	S372	R370H	370	Missense	proximal	-2	no	7.971	6.393	EPSD	ICGC;GDSC;CCLE	5.915	Down-regulation
CMGC_MAPK_p38_MAPK14_ST	O43464	HTRA2	Q16539	MAPK14	S96	E97D	97	Missense	proximal	1	no	7.175	7.503	EPSD	ICGC	5.915	Up-regulation
CMGC_MAPK_p38_MAPK14_ST	O43464	HTRA2	Q16539	MAPK14	T221	V226M	226	Missense	distal	5	no	6.807	6.986	EPSD	ICGC	5.915	Up-regulation
CMGC_MAPK_p38_MAPK14_ST	O43464	HTRA2	Q16539	MAPK14	S400	R404Q	404	Missense	distal	4	no	8.322	8.118	EPSD	ICGC;COSMIC	5.915	Down-regulation
CMGC_MAPK_p38_MAPK14_ST	O43464	HTRA2	Q16539	MAPK14	S400	G399V	399	Missense	proximal	-1	no	8.322	8.325	EPSD	ICGC	5.915	Up-regulation
CMGC_MAPK_p38_MAPK14_ST	Q92993	KAT5	Q16539	MAPK14	T77	T77A	77	Missense	central	0	yes	7.401	0.000	EPSD	ICGC;COSMIC	5.915	Loss
CMGC_MAPK_p38_MAPK14_ST	Q92993	KAT5	Q16539	MAPK14	T77	G82R	82	Missense	distal	5	no	7.401	7.346	EPSD	ICGC;COSMIC	5.915	Down-regulation
CMGC_MAPK_p38_MAPK14_ST	Q92993	KAT5	Q16539	MAPK14	S90	R87H	87	Missense	distal	-3	no	11.728	9.974	EPSD	ICGC;COSMIC	5.915	Down-regulation
CMGC_MAPK_p38_MAPK14_ST	Q92993	KAT5	Q16539	MAPK14	S90	G89D	89	Missense	proximal	-1	no	11.728	11.772	EPSD	ICGC	5.915	Up-regulation
CMGC_MAPK_p38_MAPK14_ST	P41235	HNF4A	Q16539	MAPK14	S167	G174C	174	Missense	distal	7	no	7.662	7.240	PhosphoSitePlus	ICGC	5.915	Down-regulation
CMGC_MAPK_p38_MAPK14_ST	P41235	HNF4A	Q16539	MAPK14	S167	V169I	169	Missense	proximal	2	no	7.662	7.610	PhosphoSitePlus	ICGC;GDSC	5.915	Down-regulation
CMGC_MAPK_p38_MAPK14_ST	P41235	HNF4A	Q16539	MAPK14	S378	M373L	373	Missense	distal	-5	no	11.760	12.337	EPSD	ICGC;COSMIC	5.915	Up-regulation
CMGC_MAPK_p38_MAPK14_ST	P41235	HNF4A	Q16539	MAPK14	S378	G377R	377	Missense	proximal	-1	no	11.760	11.440	EPSD	ICGC;COSMIC	5.915	Down-regulation
CMGC_MAPK_p38_MAPK14_ST	P41235	HNF4A	Q16539	MAPK14	S378	S380R	380	Missense	proximal	2	no	11.760	11.615	EPSD	ICGC;COSMIC	5.915	Down-regulation
CMGC_MAPK_p38_MAPK14_ST	P41235	HNF4A	Q16539	MAPK14	T429	P423S	423	Missense	distal	-6	no	8.288	8.895	EPSD	ICGC;COSMIC	5.915	Up-regulation
CMGC_MAPK_p38_MAPK14_ST	P05787	KRT8	Q16539	MAPK14	S27	R23C	23	Missense	distal	-4	no	5.963	6.414	EPSD	ICGC;COSMIC;GDSC	5.915	Up-regulation
CMGC_MAPK_p38_MAPK14_ST	P05787	KRT8	Q16539	MAPK14	S35	S36W	36	Missense	proximal	1	no	6.190	7.504	EPSD	ICGC	5.915	Up-regulation
CMGC_MAPK_p38_MAPK14_ST	P05787	KRT8	Q16539	MAPK14	S35	S37C	37	Missense	proximal	2	no	6.190	5.777	EPSD	ICGC;COSMIC	5.915	Loss
CMGC_MAPK_p38_MAPK14_ST	P05787	KRT8	Q16539	MAPK14	S37	S36W	36	Missense	proximal	-1	no	7.166	7.346	EPSD	ICGC	5.915	Up-regulation
CMGC_MAPK_p38_MAPK14_ST	P05787	KRT8	Q16539	MAPK14	S37	S37C	37	Missense	central	0	yes	7.166	0.000	EPSD	ICGC;COSMIC	5.915	Loss
CMGC_MAPK_p38_MAPK14_ST	P05787	KRT8	Q16539	MAPK14	S43	S36W	36	Missense	distal	-7	no	6.445	5.537	EPSD	ICGC	5.915	Loss
CMGC_MAPK_p38_MAPK14_ST	P05787	KRT8	Q16539	MAPK14	S43	G48R	48	Missense	distal	5	no	6.445	6.390	EPSD	ICGC;COSMIC	5.915	Down-regulation
CMGC_MAPK_p38_MAPK14_ST	P05787	KRT8	Q16539	MAPK14	S43	S37C	37	Missense	distal	-6	no	6.445	5.153	EPSD	ICGC;COSMIC	5.915	Loss
CMGC_MAPK_p38_MAPK14_ST	P05787	KRT8	Q16539	MAPK14	T305	R301W	301	Missense	distal	-4	no	5.836	6.465	EPSD	ICGC;COSMIC	5.915	Gain
CMGC_MAPK_p38_MAPK14_ST	P05787	KRT8	Q16539	MAPK14	S432	L435I	435	Missense	distal	3	no	8.643	8.665	EPSD	ICGC	5.915	Up-regulation
CMGC_MAPK_p38_MAPK14_ST	P05787	KRT8	Q16539	MAPK14	S451	A447T	447	Missense	distal	-4	no	7.278	7.515	EPSD	ICGC;CCLE	5.915	Up-regulation
CMGC_MAPK_p38_MAPK14_ST	P11362	FGFR1	Q16539	MAPK14	S433	Q426K	426	Missense	distal	-7	no	5.706	6.065	EPSD	ICGC	5.915	Gain
CMGC_MAPK_p38_MAPK14_ST	P11362	FGFR1	Q16539	MAPK14	S433	S434F	434	Missense	proximal	1	no	5.706	6.986	EPSD	ICGC;COSMIC	5.915	Gain
CMGC_MAPK_p38_MAPK14_ST	O15151	MDM4	Q16539	MAPK14	S20	S20F	20	Missense	central	0	yes	7.768	0.000	EPSD	ICGC;COSMIC	5.915	Loss
CMGC_MAPK_p38_MAPK14_ST	O15151	MDM4	Q16539	MAPK14	S96	D100G	100	Missense	distal	4	no	8.556	9.494	EPSD	ICGC;COSMIC	5.915	Up-regulation
CMGC_MAPK_p38_MAPK14_ST	O15151	MDM4	Q16539	MAPK14	T263	G268W	268	Missense	distal	5	no	6.163	5.214	EPSD	ICGC;COSMIC	5.915	Loss
CMGC_MAPK_p38_MAPK14_ST	O15151	MDM4	Q16539	MAPK14	T263	A257D	257	Missense	distal	-6	no	6.163	5.957	EPSD	ICGC;COSMIC	5.915	Down-regulation
CMGC_MAPK_p38_MAPK14_ST	O95644	NFATC1	Q16539	MAPK14	S117	S124L	124	Missense	distal	7	no	13.323	12.938	EPSD	ICGC;COSMIC	5.915	Down-regulation
CMGC_MAPK_p38_MAPK14_ST	O95644	NFATC1	Q16539	MAPK14	S117	R119H	119	Missense	proximal	2	no	13.323	12.940	EPSD	ICGC;COSMIC	5.915	Down-regulation
CMGC_MAPK_p38_MAPK14_ST	O95644	NFATC1	Q16539	MAPK14	S117	E121K	121	Missense	distal	4	no	13.323	12.857	EPSD	ICGC;COSMIC	5.915	Down-regulation
CMGC_MAPK_p38_MAPK14_ST	O95644	NFATC1	Q16539	MAPK14	S151	T154M	154	Missense	distal	3	no	10.719	10.743	EPSD	ICGC;COSMIC;CCLE	5.915	Up-regulation
CMGC_MAPK_p38_MAPK14_ST	O95644	NFATC1	Q16539	MAPK14	S151	S151P	151	Missense	central	0	yes	10.719	0.000	EPSD	ICGC;COSMIC	5.915	Loss
CMGC_MAPK_p38_MAPK14_ST	O95644	NFATC1	Q16539	MAPK14	S151	S158R	158	Missense	distal	7	no	10.719	10.754	EPSD	ICGC;COSMIC	5.915	Up-regulation
CMGC_MAPK_p38_MAPK14_ST	O95644	NFATC1	Q16539	MAPK14	S151	S151C	151	Missense	central	0	yes	10.719	0.000	EPSD	ICGC;COSMIC	5.915	Loss
CMGC_MAPK_p38_MAPK14_ST	O95644	NFATC1	Q16539	MAPK14	S151	R150L	150	Missense	proximal	-1	no	10.719	11.105	EPSD	ICGC	5.915	Up-regulation
CMGC_MAPK_p38_MAPK14_ST	O95644	NFATC1	Q16539	MAPK14	S151	A155S	155	Missense	distal	4	no	10.719	11.025	EPSD	ICGC	5.915	Up-regulation
CMGC_MAPK_p38_MAPK14_ST	O95644	NFATC1	Q16539	MAPK14	S151	P152L	152	Missense	proximal	1	no	10.719	2.669	EPSD	ICGC;COSMIC	5.915	Loss
CMGC_MAPK_p38_MAPK14_ST	O95644	NFATC1	Q16539	MAPK14	S151	P146S	146	Missense	distal	-5	no	10.719	10.271	EPSD	ICGC;COSMIC	5.915	Down-regulation
CMGC_MAPK_p38_MAPK14_ST	O95644	NFATC1	Q16539	MAPK14	S151	V144I	144	Missense	distal	-7	no	10.719	11.003	EPSD	ICGC;COSMIC	5.915	Up-regulation
CMGC_MAPK_p38_MAPK14_ST	O95644	NFATC1	Q16539	MAPK14	S151	T156M	156	Missense	distal	5	no	10.719	10.407	EPSD	ICGC;COSMIC	5.915	Down-regulation
CMGC_MAPK_p38_MAPK14_ST	O95644	NFATC1	Q16539	MAPK14	S151	R150W	150	Missense	proximal	-1	no	10.719	11.007	EPSD	ICGC	5.915	Up-regulation
CMGC_MAPK_p38_MAPK14_ST	O95644	NFATC1	Q16539	MAPK14	T154	T154M	154	Missense	central	0	yes	7.215	0.000	EPSD	ICGC;COSMIC;CCLE	5.915	Loss
CMGC_MAPK_p38_MAPK14_ST	O95644	NFATC1	Q16539	MAPK14	T154	S151P	151	Missense	distal	-3	no	7.215	6.451	EPSD	ICGC;COSMIC	5.915	Down-regulation
CMGC_MAPK_p38_MAPK14_ST	O95644	NFATC1	Q16539	MAPK14	T154	S158R	158	Missense	distal	4	no	7.215	6.498	EPSD	ICGC;COSMIC	5.915	Down-regulation
CMGC_MAPK_p38_MAPK14_ST	O95644	NFATC1	Q16539	MAPK14	T154	S151C	151	Missense	distal	-3	no	7.215	5.532	EPSD	ICGC;COSMIC	5.915	Loss
CMGC_MAPK_p38_MAPK14_ST	O95644	NFATC1	Q16539	MAPK14	T154	R150L	150	Missense	distal	-4	no	7.215	7.804	EPSD	ICGC	5.915	Up-regulation
CMGC_MAPK_p38_MAPK14_ST	O95644	NFATC1	Q16539	MAPK14	T154	A155S	155	Missense	proximal	1	no	7.215	6.249	EPSD	ICGC	5.915	Down-regulation
CMGC_MAPK_p38_MAPK14_ST	O95644	NFATC1	Q16539	MAPK14	T154	P152L	152	Missense	proximal	-2	no	7.215	5.835	EPSD	ICGC;COSMIC	5.915	Loss
CMGC_MAPK_p38_MAPK14_ST	O95644	NFATC1	Q16539	MAPK14	T154	T156M	156	Missense	proximal	2	no	7.215	7.196	EPSD	ICGC;COSMIC	5.915	Down-regulation
CMGC_MAPK_p38_MAPK14_ST	O95644	NFATC1	Q16539	MAPK14	T154	R150W	150	Missense	distal	-4	no	7.215	7.844	EPSD	ICGC	5.915	Up-regulation
CMGC_MAPK_p38_MAPK14_ST	O95644	NFATC1	Q16539	MAPK14	S172	A174T	174	Missense	proximal	2	no	13.182	13.210	PhosphoSitePlus	ICGC;COSMIC	5.915	Up-regulation
CMGC_MAPK_p38_MAPK14_ST	O95644	NFATC1	Q16539	MAPK14	S172	L177M	177	Missense	distal	5	no	13.182	13.651	PhosphoSitePlus	ICGC;COSMIC	5.915	Up-regulation
CMGC_MAPK_p38_MAPK14_ST	O95644	NFATC1	Q16539	MAPK14	S172	L171P	171	Missense	proximal	-1	no	13.182	12.997	PhosphoSitePlus	ICGC	5.915	Down-regulation
CMGC_MAPK_p38_MAPK14_ST	O95644	NFATC1	Q16539	MAPK14	S172	A174V	174	Missense	proximal	2	no	13.182	13.018	PhosphoSitePlus	ICGC	5.915	Down-regulation
CMGC_MAPK_p38_MAPK14_ST	O95644	NFATC1	Q16539	MAPK14	S172	S176N	176	Missense	distal	4	no	13.182	12.665	PhosphoSitePlus	ICGC	5.915	Down-regulation
CMGC_MAPK_p38_MAPK14_ST	O95644	NFATC1	Q16539	MAPK14	S172	D167Y	167	Missense	distal	-5	no	13.182	13.007	PhosphoSitePlus	ICGC;COSMIC	5.915	Down-regulation
CMGC_MAPK_p38_MAPK14_ST	O95644	NFATC1	Q16539	MAPK14	S175	S181N	181	Missense	distal	6	no	6.910	6.889	EPSD	ICGC;COSMIC	5.915	Down-regulation
CMGC_MAPK_p38_MAPK14_ST	O95644	NFATC1	Q16539	MAPK14	S175	A174T	174	Missense	proximal	-1	no	6.910	6.967	EPSD	ICGC;COSMIC	5.915	Up-regulation
CMGC_MAPK_p38_MAPK14_ST	O95644	NFATC1	Q16539	MAPK14	S175	C182R	182	Missense	distal	7	no	6.910	7.509	EPSD	ICGC	5.915	Up-regulation
CMGC_MAPK_p38_MAPK14_ST	O95644	NFATC1	Q16539	MAPK14	S175	L177M	177	Missense	proximal	2	no	6.910	7.145	EPSD	ICGC;COSMIC	5.915	Up-regulation
CMGC_MAPK_p38_MAPK14_ST	O95644	NFATC1	Q16539	MAPK14	S175	L171P	171	Missense	distal	-4	no	6.910	6.398	EPSD	ICGC	5.915	Down-regulation
CMGC_MAPK_p38_MAPK14_ST	O95644	NFATC1	Q16539	MAPK14	S175	A174V	174	Missense	proximal	-1	no	6.910	7.066	EPSD	ICGC	5.915	Up-regulation
CMGC_MAPK_p38_MAPK14_ST	O95644	NFATC1	Q16539	MAPK14	S175	S176N	176	Missense	proximal	1	no	6.910	6.390	EPSD	ICGC	5.915	Down-regulation
CMGC_MAPK_p38_MAPK14_ST	O95644	NFATC1	Q16539	MAPK14	S178	C182R	182	Missense	distal	4	no	5.489	5.923	EPSD	ICGC	5.915	Gain
CMGC_MAPK_p38_MAPK14_ST	O95644	NFATC1	Q16539	MAPK14	S184	S181N	181	Missense	distal	-3	no	6.285	5.138	EPSD	ICGC;COSMIC	5.915	Loss
CMGC_MAPK_p38_MAPK14_ST	O95644	NFATC1	Q16539	MAPK14	S184	E190K	190	Missense	distal	6	no	6.285	6.280	EPSD	ICGC;COSMIC	5.915	Down-regulation
CMGC_MAPK_p38_MAPK14_ST	O95644	NFATC1	Q16539	MAPK14	S184	C182R	182	Missense	proximal	-2	no	6.285	7.221	EPSD	ICGC	5.915	Up-regulation
CMGC_MAPK_p38_MAPK14_ST	O95644	NFATC1	Q16539	MAPK14	S184	L177M	177	Missense	distal	-7	no	6.285	6.550	EPSD	ICGC;COSMIC	5.915	Up-regulation
CMGC_MAPK_p38_MAPK14_ST	O95644	NFATC1	Q16539	MAPK14	S184	E185D	185	Missense	proximal	1	no	6.285	6.613	EPSD	ICGC;COSMIC	5.915	Up-regulation
CMGC_MAPK_p38_MAPK14_ST	O95644	NFATC1	Q16539	MAPK14	S184	S187A	187	Missense	distal	3	no	6.285	6.300	EPSD	ICGC;COSMIC	5.915	Up-regulation
CMGC_MAPK_p38_MAPK14_ST	O95644	NFATC1	Q16539	MAPK14	S211	V210M	210	Missense	proximal	-1	no	10.863	10.771	EPSD	ICGC;COSMIC	5.915	Down-regulation
CMGC_MAPK_p38_MAPK14_ST	O95644	NFATC1	Q16539	MAPK14	S211	V210L	210	Missense	proximal	-1	no	10.863	10.926	EPSD	ICGC;COSMIC	5.915	Up-regulation
CMGC_MAPK_p38_MAPK14_ST	O95644	NFATC1	Q16539	MAPK14	S211	P208S	208	Missense	distal	-3	no	10.863	11.627	EPSD	ICGC	5.915	Up-regulation
CMGC_MAPK_p38_MAPK14_ST	O95644	NFATC1	Q16539	MAPK14	S211	P208L	208	Missense	distal	-3	no	10.863	9.896	EPSD	ICGC;COSMIC	5.915	Down-regulation
CMGC_MAPK_p38_MAPK14_ST	O95644	NFATC1	Q16539	MAPK14	S233	G232C	232	Missense	proximal	-1	no	10.753	10.696	EPSD	ICGC;COSMIC	5.915	Down-regulation
CMGC_MAPK_p38_MAPK14_ST	O95644	NFATC1	Q16539	MAPK14	S233	P234L	234	Missense	proximal	1	no	10.753	2.703	EPSD	ICGC;COSMIC	5.915	Loss
CMGC_MAPK_p38_MAPK14_ST	O95644	NFATC1	Q16539	MAPK14	S237	A244T	244	Missense	distal	7	no	10.127	9.784	EPSD	ICGC;COSMIC	5.915	Down-regulation
CMGC_MAPK_p38_MAPK14_ST	O95644	NFATC1	Q16539	MAPK14	S237	P242S	242	Missense	distal	5	no	10.127	10.577	EPSD	ICGC;COSMIC	5.915	Up-regulation
CMGC_MAPK_p38_MAPK14_ST	O95644	NFATC1	Q16539	MAPK14	S237	G232C	232	Missense	distal	-5	no	10.127	10.447	EPSD	ICGC;COSMIC	5.915	Up-regulation
CMGC_MAPK_p38_MAPK14_ST	O95644	NFATC1	Q16539	MAPK14	S237	P242L	242	Missense	distal	5	no	10.127	9.630	EPSD	ICGC;COSMIC	5.915	Down-regulation
CMGC_MAPK_p38_MAPK14_ST	O95644	NFATC1	Q16539	MAPK14	S237	P234L	234	Missense	distal	-3	no	10.127	9.159	EPSD	ICGC;COSMIC	5.915	Down-regulation
CMGC_MAPK_p38_MAPK14_ST	O95644	NFATC1	Q16539	MAPK14	S239	A244T	244	Missense	distal	5	no	6.025	6.498	EPSD	ICGC;COSMIC	5.915	Up-regulation
CMGC_MAPK_p38_MAPK14_ST	O95644	NFATC1	Q16539	MAPK14	S239	V246L	246	Missense	distal	7	no	6.025	5.727	EPSD	ICGC;COSMIC	5.915	Loss
CMGC_MAPK_p38_MAPK14_ST	O95644	NFATC1	Q16539	MAPK14	S239	P242S	242	Missense	distal	3	no	6.025	5.985	EPSD	ICGC;COSMIC	5.915	Down-regulation
CMGC_MAPK_p38_MAPK14_ST	O95644	NFATC1	Q16539	MAPK14	S239	V246I	246	Missense	distal	7	no	6.025	5.379	EPSD	ICGC;COSMIC	5.915	Loss
CMGC_MAPK_p38_MAPK14_ST	O95644	NFATC1	Q16539	MAPK14	S239	G232C	232	Missense	distal	-7	no	6.025	5.532	EPSD	ICGC;COSMIC	5.915	Loss
CMGC_MAPK_p38_MAPK14_ST	O95644	NFATC1	Q16539	MAPK14	S239	P242L	242	Missense	distal	3	no	6.025	6.059	EPSD	ICGC;COSMIC	5.915	Up-regulation
CMGC_MAPK_p38_MAPK14_ST	O95644	NFATC1	Q16539	MAPK14	S239	P234L	234	Missense	distal	-5	no	6.025	6.307	EPSD	ICGC;COSMIC	5.915	Up-regulation
CMGC_MAPK_p38_MAPK14_ST	O95644	NFATC1	Q16539	MAPK14	S241	A244T	244	Missense	distal	3	no	13.363	13.362	EPSD	ICGC;COSMIC	5.915	Down-regulation
CMGC_MAPK_p38_MAPK14_ST	O95644	NFATC1	Q16539	MAPK14	S241	V246L	246	Missense	distal	5	no	13.363	13.072	EPSD	ICGC;COSMIC	5.915	Down-regulation
CMGC_MAPK_p38_MAPK14_ST	O95644	NFATC1	Q16539	MAPK14	S241	P242S	242	Missense	proximal	1	no	13.363	6.079	EPSD	ICGC;COSMIC	5.915	Down-regulation
CMGC_MAPK_p38_MAPK14_ST	O95644	NFATC1	Q16539	MAPK14	S241	V246I	246	Missense	distal	5	no	13.363	12.927	EPSD	ICGC;COSMIC	5.915	Down-regulation
CMGC_MAPK_p38_MAPK14_ST	O95644	NFATC1	Q16539	MAPK14	S241	P242L	242	Missense	proximal	1	no	13.363	5.312	EPSD	ICGC;COSMIC	5.915	Loss
CMGC_MAPK_p38_MAPK14_ST	O95644	NFATC1	Q16539	MAPK14	S241	P234L	234	Missense	distal	-7	no	13.363	13.169	EPSD	ICGC;COSMIC	5.915	Down-regulation
CMGC_MAPK_p38_MAPK14_ST	O95644	NFATC1	Q16539	MAPK14	S245	V246L	246	Missense	proximal	1	no	4.948	6.176	EPSD	ICGC;COSMIC	5.915	Gain
CMGC_MAPK_p38_MAPK14_ST	O95644	NFATC1	Q16539	MAPK14	S245	V246I	246	Missense	proximal	1	no	4.948	6.548	EPSD	ICGC;COSMIC	5.915	Gain
CMGC_MAPK_p38_MAPK14_ST	O95644	NFATC1	Q16539	MAPK14	S250	A244T	244	Missense	distal	-6	no	6.694	6.964	EPSD	ICGC;COSMIC	5.915	Up-regulation
CMGC_MAPK_p38_MAPK14_ST	O95644	NFATC1	Q16539	MAPK14	S250	V246L	246	Missense	distal	-4	no	6.694	6.972	EPSD	ICGC;COSMIC	5.915	Up-regulation
CMGC_MAPK_p38_MAPK14_ST	O95644	NFATC1	Q16539	MAPK14	S250	E249D	249	Missense	proximal	-1	no	6.694	7.039	EPSD	ICGC;COSMIC	5.915	Up-regulation
CMGC_MAPK_p38_MAPK14_ST	O95644	NFATC1	Q16539	MAPK14	S250	V246I	246	Missense	distal	-4	no	6.694	6.539	EPSD	ICGC;COSMIC	5.915	Down-regulation
CMGC_MAPK_p38_MAPK14_ST	O95644	NFATC1	Q16539	MAPK14	S261	P262L	262	Missense	proximal	1	no	13.340	5.289	EPSD	ICGC;COSMIC	5.915	Loss
CMGC_MAPK_p38_MAPK14_ST	O95644	NFATC1	Q16539	MAPK14	S278	R273L	273	Missense	distal	-5	no	11.081	11.591	EPSD	ICGC;COSMIC	5.915	Up-regulation
CMGC_MAPK_p38_MAPK14_ST	O95644	NFATC1	Q16539	MAPK14	S278	H281D	281	Missense	distal	3	no	11.081	11.033	EPSD	ICGC;COSMIC	5.915	Down-regulation
CMGC_MAPK_p38_MAPK14_ST	O95644	NFATC1	Q16539	MAPK14	S278	G272V	272	Missense	distal	-6	no	11.081	10.531	EPSD	ICGC;COSMIC	5.915	Down-regulation
CMGC_MAPK_p38_MAPK14_ST	O95644	NFATC1	Q16539	MAPK14	S278	P275S	275	Missense	distal	-3	no	11.081	11.845	EPSD	ICGC	5.915	Up-regulation
CMGC_MAPK_p38_MAPK14_ST	O95644	NFATC1	Q16539	MAPK14	S278	P276A	276	Missense	proximal	-2	no	11.081	10.418	EPSD	ICGC;COSMIC	5.915	Down-regulation
CMGC_MAPK_p38_MAPK14_ST	O95644	NFATC1	Q16539	MAPK14	S278	R273Q	273	Missense	distal	-5	no	11.081	11.038	EPSD	ICGC	5.915	Down-regulation
CMGC_MAPK_p38_MAPK14_ST	O95644	NFATC1	Q16539	MAPK14	S278	H280Y	280	Missense	proximal	2	no	11.081	11.284	EPSD	ICGC;COSMIC	5.915	Up-regulation
CMGC_MAPK_p38_MAPK14_ST	O95644	NFATC1	Q16539	MAPK14	S282	H281D	281	Missense	proximal	-1	no	12.738	12.947	EPSD	ICGC;COSMIC	5.915	Up-regulation
CMGC_MAPK_p38_MAPK14_ST	O95644	NFATC1	Q16539	MAPK14	S282	P275S	275	Missense	distal	-7	no	12.738	12.825	EPSD	ICGC	5.915	Up-regulation
CMGC_MAPK_p38_MAPK14_ST	O95644	NFATC1	Q16539	MAPK14	S282	P276A	276	Missense	distal	-6	no	12.738	12.802	EPSD	ICGC;COSMIC	5.915	Up-regulation
CMGC_MAPK_p38_MAPK14_ST	O95644	NFATC1	Q16539	MAPK14	S282	S286P	286	Missense	distal	4	no	12.738	12.298	EPSD	ICGC;COSMIC	5.915	Down-regulation
CMGC_MAPK_p38_MAPK14_ST	O95644	NFATC1	Q16539	MAPK14	S282	H280Y	280	Missense	proximal	-2	no	12.738	14.518	EPSD	ICGC;COSMIC	5.915	Up-regulation
CMGC_MAPK_p38_MAPK14_ST	O95644	NFATC1	Q16539	MAPK14	S282	G289S	289	Missense	distal	7	no	12.738	12.881	EPSD	ICGC;COSMIC	5.915	Up-regulation
CMGC_MAPK_p38_MAPK14_ST	O95644	NFATC1	Q16539	MAPK14	T284	H281D	281	Missense	distal	-3	no	10.203	10.456	EPSD	ICGC;COSMIC	5.915	Up-regulation
CMGC_MAPK_p38_MAPK14_ST	O95644	NFATC1	Q16539	MAPK14	T284	S286P	286	Missense	proximal	2	no	10.203	9.827	EPSD	ICGC;COSMIC	5.915	Down-regulation
CMGC_MAPK_p38_MAPK14_ST	O95644	NFATC1	Q16539	MAPK14	T284	S290F	290	Missense	distal	6	no	10.203	9.846	EPSD	ICGC;COSMIC	5.915	Down-regulation
CMGC_MAPK_p38_MAPK14_ST	O95644	NFATC1	Q16539	MAPK14	T284	H280Y	280	Missense	distal	-4	no	10.203	9.978	EPSD	ICGC;COSMIC	5.915	Down-regulation
CMGC_MAPK_p38_MAPK14_ST	O95644	NFATC1	Q16539	MAPK14	T284	P291T	291	Missense	distal	7	no	10.203	10.104	EPSD	ICGC;COSMIC	5.915	Down-regulation
CMGC_MAPK_p38_MAPK14_ST	O95644	NFATC1	Q16539	MAPK14	T284	G289S	289	Missense	distal	5	no	10.203	10.459	EPSD	ICGC;COSMIC	5.915	Up-regulation
CMGC_MAPK_p38_MAPK14_ST	O95644	NFATC1	Q16539	MAPK14	S286	H281D	281	Missense	distal	-5	no	10.865	10.726	EPSD	ICGC;COSMIC	5.915	Down-regulation
CMGC_MAPK_p38_MAPK14_ST	O95644	NFATC1	Q16539	MAPK14	S286	S286P	286	Missense	central	0	yes	10.865	0.000	EPSD	ICGC;COSMIC	5.915	Loss
CMGC_MAPK_p38_MAPK14_ST	O95644	NFATC1	Q16539	MAPK14	S286	S290F	290	Missense	distal	4	no	10.865	9.290	EPSD	ICGC;COSMIC	5.915	Down-regulation
CMGC_MAPK_p38_MAPK14_ST	O95644	NFATC1	Q16539	MAPK14	S286	H280Y	280	Missense	distal	-6	no	10.865	11.168	EPSD	ICGC;COSMIC	5.915	Up-regulation
CMGC_MAPK_p38_MAPK14_ST	O95644	NFATC1	Q16539	MAPK14	S286	P291T	291	Missense	distal	5	no	10.865	11.149	EPSD	ICGC;COSMIC	5.915	Up-regulation
CMGC_MAPK_p38_MAPK14_ST	O95644	NFATC1	Q16539	MAPK14	S286	G289S	289	Missense	distal	3	no	10.865	10.823	EPSD	ICGC;COSMIC	5.915	Down-regulation
CMGC_MAPK_p38_MAPK14_ST	O95644	NFATC1	Q16539	MAPK14	S290	V295M	295	Missense	distal	5	no	9.130	9.308	EPSD	ICGC	5.915	Up-regulation
CMGC_MAPK_p38_MAPK14_ST	O95644	NFATC1	Q16539	MAPK14	S290	D297Y	297	Missense	distal	7	no	9.130	9.150	EPSD	ICGC;COSMIC	5.915	Up-regulation
CMGC_MAPK_p38_MAPK14_ST	O95644	NFATC1	Q16539	MAPK14	S290	S286P	286	Missense	distal	-4	no	9.130	9.218	EPSD	ICGC;COSMIC	5.915	Up-regulation
CMGC_MAPK_p38_MAPK14_ST	O95644	NFATC1	Q16539	MAPK14	S290	T296I	296	Missense	distal	6	no	9.130	8.882	EPSD	ICGC	5.915	Down-regulation
CMGC_MAPK_p38_MAPK14_ST	O95644	NFATC1	Q16539	MAPK14	S290	S290F	290	Missense	central	0	yes	9.130	0.000	EPSD	ICGC;COSMIC	5.915	Loss
CMGC_MAPK_p38_MAPK14_ST	O95644	NFATC1	Q16539	MAPK14	S290	P291T	291	Missense	proximal	1	no	9.130	1.677	EPSD	ICGC;COSMIC	5.915	Loss
CMGC_MAPK_p38_MAPK14_ST	O95644	NFATC1	Q16539	MAPK14	S290	G289S	289	Missense	proximal	-1	no	9.130	8.917	EPSD	ICGC;COSMIC	5.915	Down-regulation
CMGC_MAPK_p38_MAPK14_ST	O95644	NFATC1	Q16539	MAPK14	S359	P362L	362	Missense	distal	3	no	6.576	6.610	EPSD	ICGC;COSMIC	5.915	Up-regulation
CMGC_MAPK_p38_MAPK14_ST	O95644	NFATC1	Q16539	MAPK14	S359	G354E	354	Missense	distal	-5	no	6.576	5.944	EPSD	ICGC;COSMIC	5.915	Down-regulation
CMGC_MAPK_p38_MAPK14_ST	O95644	NFATC1	Q16539	MAPK14	S359	P361L	361	Missense	proximal	2	no	6.576	6.463	EPSD	ICGC	5.915	Down-regulation
CMGC_MAPK_p38_MAPK14_ST	O95644	NFATC1	Q16539	MAPK14	S359	P363S	363	Missense	distal	4	no	6.576	7.015	EPSD	ICGC	5.915	Up-regulation
CMGC_MAPK_p38_MAPK14_ST	O95644	NFATC1	Q16539	MAPK14	S359	A364G	364	Missense	distal	5	no	6.576	6.959	EPSD	ICGC;COSMIC	5.915	Up-regulation
CMGC_MAPK_p38_MAPK14_ST	O95644	NFATC1	Q16539	MAPK14	S403	A397V	397	Missense	distal	-6	no	12.139	11.651	EPSD	ICGC;COSMIC	5.915	Down-regulation
CMGC_MAPK_p38_MAPK14_ST	O95644	NFATC1	Q16539	MAPK14	S403	P410T	410	Missense	distal	7	no	12.139	12.039	EPSD	ICGC;COSMIC	5.915	Down-regulation
CMGC_MAPK_p38_MAPK14_ST	O95644	NFATC1	Q16539	MAPK14	S403	P404S	404	Missense	proximal	1	no	12.139	4.855	EPSD	ICGC;COSMIC	5.915	Loss
CMGC_MAPK_p38_MAPK14_ST	O95644	NFATC1	Q16539	MAPK14	S403	S409R	409	Missense	distal	6	no	12.139	12.138	EPSD	ICGC;COSMIC	5.915	Down-regulation
CMGC_MAPK_p38_MAPK14_ST	O95644	NFATC1	Q16539	MAPK14	S409	P410T	410	Missense	proximal	1	no	13.393	5.939	EPSD	ICGC;COSMIC	5.915	Down-regulation
CMGC_MAPK_p38_MAPK14_ST	O95644	NFATC1	Q16539	MAPK14	S409	P404S	404	Missense	distal	-5	no	13.393	12.945	EPSD	ICGC;COSMIC	5.915	Down-regulation
CMGC_MAPK_p38_MAPK14_ST	O95644	NFATC1	Q16539	MAPK14	S409	P413S	413	Missense	distal	4	no	13.393	13.832	EPSD	ICGC;COSMIC	5.915	Up-regulation
CMGC_MAPK_p38_MAPK14_ST	O95644	NFATC1	Q16539	MAPK14	S409	S409R	409	Missense	central	0	yes	13.393	0.000	EPSD	ICGC;COSMIC	5.915	Loss
CMGC_MAPK_p38_MAPK14_ST	O95644	NFATC1	Q16539	MAPK14	S670	R667S	667	Missense	distal	-3	no	11.987	11.474	EPSD	ICGC;COSMIC	5.915	Down-regulation
CMGC_MAPK_p38_MAPK14_ST	O95644	NFATC1	Q16539	MAPK14	S670	V674I	674	Missense	distal	4	no	11.987	11.938	EPSD	ICGC;COSMIC	5.915	Down-regulation
CMGC_MAPK_p38_MAPK14_ST	O95644	NFATC1	Q16539	MAPK14	S670	V672F	672	Missense	proximal	2	no	11.987	11.749	EPSD	ICGC;COSMIC	5.915	Down-regulation
CMGC_MAPK_p38_MAPK14_ST	O95644	NFATC1	Q16539	MAPK14	S670	V674F	674	Missense	distal	4	no	11.987	11.152	EPSD	ICGC;COSMIC	5.915	Down-regulation
CMGC_MAPK_p38_MAPK14_ST	O95644	NFATC1	Q16539	MAPK14	S670	S670N	670	Missense	central	0	yes	11.987	0.000	EPSD	ICGC;COSMIC	5.915	Loss
CMGC_MAPK_p38_MAPK14_ST	O95644	NFATC1	Q16539	MAPK14	S887	A890D	890	Missense	distal	3	no	12.395	12.432	EPSD	ICGC;COSMIC	5.915	Up-regulation
CMGC_MAPK_p38_MAPK14_ST	O95644	NFATC1	Q16539	MAPK14	S887	R893Q	893	Missense	distal	6	no	12.395	12.407	EPSD	ICGC	5.915	Up-regulation
CMGC_MAPK_p38_MAPK14_ST	O95644	NFATC1	Q16539	MAPK14	S887	R883C	883	Missense	distal	-4	no	12.395	12.845	EPSD	ICGC	5.915	Up-regulation
CMGC_MAPK_p38_MAPK14_ST	O95644	NFATC1	Q16539	MAPK14	S903	P910L	910	Missense	distal	7	no	10.463	10.300	EPSD	ICGC;COSMIC	5.915	Down-regulation
CMGC_MAPK_p38_MAPK14_ST	Q99626	CDX2	Q16539	MAPK14	S60	P66L	66	Missense	distal	6	no	12.446	12.307	EPSD	ICGC;COSMIC	5.915	Down-regulation
CMGC_MAPK_p38_MAPK14_ST	Q99626	CDX2	Q16539	MAPK14	S283	P284L	284	Missense	proximal	1	no	10.883	2.833	PhosphoSitePlus	ICGC	5.915	Loss
CMGC_MAPK_p38_MAPK14_ST	Q99626	CDX2	Q16539	MAPK14	S283	P284T	284	Missense	proximal	1	no	10.883	3.430	PhosphoSitePlus	ICGC	5.915	Loss
CMGC_MAPK_p38_MAPK14_ST	Q99626	CDX2	Q16539	MAPK14	S286	P293S	293	Missense	distal	7	no	8.061	8.283	EPSD	ICGC;COSMIC	5.915	Up-regulation
CMGC_MAPK_p38_MAPK14_ST	Q99626	CDX2	Q16539	MAPK14	S286	P284L	284	Missense	proximal	-2	no	8.061	6.681	EPSD	ICGC	5.915	Down-regulation
CMGC_MAPK_p38_MAPK14_ST	Q99626	CDX2	Q16539	MAPK14	S286	P284T	284	Missense	proximal	-2	no	8.061	7.341	EPSD	ICGC	5.915	Down-regulation
CMGC_MAPK_p38_MAPK14_ST	Q15075	EEA1	Q16539	MAPK14	T25	T25N	25	Missense	central	0	yes	12.865	0.000	EPSD	ICGC	5.915	Loss
CMGC_MAPK_p38_MAPK14_ST	Q15075	EEA1	Q16539	MAPK14	T241	M237I	237	Missense	distal	-4	no	5.824	5.920	EPSD	ICGC;COSMIC	5.915	Gain
CMGC_MAPK_p38_MAPK14_ST	Q15075	EEA1	Q16539	MAPK14	S354	Q347K	347	Missense	distal	-7	no	7.011	7.370	EPSD	ICGC;COSMIC	5.915	Up-regulation
CMGC_MAPK_p38_MAPK14_ST	Q15075	EEA1	Q16539	MAPK14	S354	L360M	360	Missense	distal	6	no	7.011	7.186	EPSD	ICGC	5.915	Up-regulation
CMGC_MAPK_p38_MAPK14_ST	Q15075	EEA1	Q16539	MAPK14	T621	D614E	614	Missense	distal	-7	no	5.549	6.131	EPSD	ICGC	5.915	Gain
CMGC_MAPK_p38_MAPK14_ST	Q15075	EEA1	Q16539	MAPK14	S1265	R1262W	1262	Missense	distal	-3	no	6.316	3.959	EPSD	ICGC;COSMIC	5.915	Loss
CMGC_MAPK_p38_MAPK14_ST	Q15075	EEA1	Q16539	MAPK14	S1265	T1271M	1271	Missense	distal	6	no	6.316	6.327	EPSD	ICGC;COSMIC	5.915	Up-regulation
CMGC_MAPK_p38_MAPK14_ST	Q15075	EEA1	Q16539	MAPK14	S1386	F1381L	1381	Missense	distal	-5	no	7.073	7.017	EPSD	ICGC;COSMIC	5.915	Down-regulation
CMGC_MAPK_p38_MAPK14_ST	Q15075	EEA1	Q16539	MAPK14	T1392	P1398H	1398	Missense	distal	6	no	13.215	13.095	PhosphoSitePlus	ICGC;COSMIC	5.915	Down-regulation
CMGC_MAPK_p38_MAPK14_ST	Q15075	EEA1	Q16539	MAPK14	T1392	P1398T	1398	Missense	distal	6	no	13.215	13.240	PhosphoSitePlus	ICGC	5.915	Up-regulation
CMGC_MAPK_p38_MAPK14_ST	P13726	F3	Q16539	MAPK14	S120	A121D	121	Missense	proximal	1	no	6.215	5.101	EPSD	ICGC	5.915	Loss
CMGC_MAPK_p38_MAPK14_ST	P13726	F3	Q16539	MAPK14	S120	G113E	113	Missense	distal	-7	no	6.215	6.433	EPSD	ICGC	5.915	Up-regulation
CMGC_MAPK_p38_MAPK14_ST	O75676	RPS6KA4	Q16539	MAPK14	S196	R193W	193	Missense	distal	-3	no	7.170	4.813	PhosphoSitePlus	ICGC;COSMIC	5.915	Loss
CMGC_MAPK_p38_MAPK14_ST	O75676	RPS6KA4	Q16539	MAPK14	S196	G199V	199	Missense	distal	3	no	7.170	7.171	PhosphoSitePlus	ICGC	5.915	Up-regulation
CMGC_MAPK_p38_MAPK14_ST	O75676	RPS6KA4	Q16539	MAPK14	S196	R193Q	193	Missense	distal	-3	no	7.170	5.391	PhosphoSitePlus	ICGC;COSMIC;GDSC;CCLE	5.915	Loss
CMGC_MAPK_p38_MAPK14_ST	O75676	RPS6KA4	Q16539	MAPK14	T336	R337W	337	Missense	proximal	1	no	4.166	6.132	EPSD	ICGC;COSMIC	5.915	Gain
CMGC_MAPK_p38_MAPK14_ST	O75676	RPS6KA4	Q16539	MAPK14	S343	R337W	337	Missense	distal	-6	no	13.382	12.064	EPSD	ICGC;COSMIC	5.915	Down-regulation
CMGC_MAPK_p38_MAPK14_ST	O75676	RPS6KA4	Q16539	MAPK14	S347	R354L	354	Missense	distal	7	no	13.505	13.085	EPSD	ICGC;COSMIC	5.915	Down-regulation
CMGC_MAPK_p38_MAPK14_ST	O75676	RPS6KA4	Q16539	MAPK14	S347	R354Q	354	Missense	distal	7	no	13.505	13.311	EPSD	ICGC;COSMIC	5.915	Down-regulation
CMGC_MAPK_p38_MAPK14_ST	O75676	RPS6KA4	Q16539	MAPK14	S360	R354L	354	Missense	distal	-6	no	7.805	6.692	EPSD	ICGC;COSMIC	5.915	Down-regulation
CMGC_MAPK_p38_MAPK14_ST	O75676	RPS6KA4	Q16539	MAPK14	S360	R354Q	354	Missense	distal	-6	no	7.805	7.135	EPSD	ICGC;COSMIC	5.915	Down-regulation
CMGC_MAPK_p38_MAPK14_ST	O75676	RPS6KA4	Q16539	MAPK14	T542	G544V	544	Missense	proximal	2	no	8.890	8.691	EPSD	ICGC;COSMIC	5.915	Down-regulation
CMGC_MAPK_p38_MAPK14_ST	O75676	RPS6KA4	Q16539	MAPK14	T568	L573P	573	Missense	distal	5	no	11.294	11.791	EPSD	ICGC;COSMIC	5.915	Up-regulation
CMGC_MAPK_p38_MAPK14_ST	O75676	RPS6KA4	Q16539	MAPK14	S672	G670D	670	Missense	proximal	-2	no	6.445	5.694	EPSD	ICGC;COSMIC	5.915	Loss
CMGC_MAPK_p38_MAPK14_ST	O75676	RPS6KA4	Q16539	MAPK14	S682	D689N	689	Missense	distal	7	no	12.080	11.759	EPSD	ICGC;COSMIC	5.915	Down-regulation
CMGC_MAPK_p38_MAPK14_ST	O75676	RPS6KA4	Q16539	MAPK14	T687	D689N	689	Missense	proximal	2	no	10.489	10.719	EPSD	ICGC;COSMIC	5.915	Up-regulation
CMGC_MAPK_p38_MAPK14_ST	P22415	USF1	Q16539	MAPK14	S186	S186Y	186	Missense	central	0	yes	10.311	0.000	EPSD	ICGC;COSMIC	5.915	Loss
CMGC_MAPK_p38_MAPK14_ST	P22415	USF1	Q16539	MAPK14	S186	S186F	186	Missense	central	0	yes	10.311	0.000	EPSD	ICGC	5.915	Loss
CMGC_MAPK_p38_MAPK14_ST	P10275	AR	Q16539	MAPK14	S96	E93K	93	Missense	distal	-3	no	7.133	6.740	EPSD	ICGC	5.915	Down-regulation
CMGC_MAPK_p38_MAPK14_ST	P10275	AR	Q16539	MAPK14	S258	G260V	260	Missense	proximal	2	no	8.031	7.832	EPSD	ICGC;COSMIC	5.915	Down-regulation
CMGC_MAPK_p38_MAPK14_ST	P10275	AR	Q16539	MAPK14	T282	A288T	288	Missense	distal	6	no	10.084	10.066	EPSD	ICGC;COSMIC	5.915	Down-regulation
CMGC_MAPK_p38_MAPK14_ST	P10275	AR	Q16539	MAPK14	T282	R280L	280	Missense	proximal	-2	no	10.084	9.392	EPSD	ICGC	5.915	Down-regulation
CMGC_MAPK_p38_MAPK14_ST	P10275	AR	Q16539	MAPK14	T282	A288D	288	Missense	distal	6	no	10.084	10.008	EPSD	ICGC;COSMIC	5.915	Down-regulation
CMGC_MAPK_p38_MAPK14_ST	P10275	AR	Q16539	MAPK14	S310	T317A	317	Missense	distal	7	no	10.302	10.646	EPSD	ICGC;COSMIC	5.915	Up-regulation
CMGC_MAPK_p38_MAPK14_ST	P10275	AR	Q16539	MAPK14	S310	T303S	303	Missense	distal	-7	no	10.302	10.372	EPSD	ICGC;COSMIC	5.915	Up-regulation
CMGC_MAPK_p38_MAPK14_ST	P10275	AR	Q16539	MAPK14	S310	G314R	314	Missense	distal	4	no	10.302	9.817	EPSD	ICGC	5.915	Down-regulation
CMGC_MAPK_p38_MAPK14_ST	P10275	AR	Q16539	MAPK14	S330	A333S	333	Missense	distal	3	no	6.855	6.841	EPSD	ICGC;COSMIC	5.915	Down-regulation
CMGC_MAPK_p38_MAPK14_ST	P10275	AR	Q16539	MAPK14	S516	Y514H	514	Missense	proximal	-2	no	10.977	9.196	EPSD	ICGC;GDSC;CCLE	5.915	Down-regulation
CMGC_MAPK_p38_MAPK14_ST	P10275	AR	Q16539	MAPK14	S516	S516I	516	Missense	central	0	yes	10.977	0.000	EPSD	ICGC	5.915	Loss
CMGC_MAPK_p38_MAPK14_ST	P10275	AR	Q16539	MAPK14	S516	V509L	509	Missense	distal	-7	no	10.977	11.401	EPSD	ICGC;COSMIC	5.915	Up-regulation
CMGC_MAPK_p38_MAPK14_ST	P06400	RB1	Q16539	MAPK14	T5	A10S	10	Missense	distal	5	no	10.335	10.974	EPSD	ICGC	5.915	Up-regulation
CMGC_MAPK_p38_MAPK14_ST	P06400	RB1	Q16539	MAPK14	T5	A11T	11	Missense	distal	6	no	10.335	10.318	EPSD	ICGC;COSMIC	5.915	Down-regulation
CMGC_MAPK_p38_MAPK14_ST	P06400	RB1	Q16539	MAPK14	S149	L151P	151	Missense	proximal	2	no	6.456	6.568	EPSD	ICGC;COSMIC	5.915	Up-regulation
CMGC_MAPK_p38_MAPK14_ST	P06400	RB1	Q16539	MAPK14	S149	A147V	147	Missense	proximal	-2	no	6.456	6.041	EPSD	ICGC;COSMIC	5.915	Down-regulation
CMGC_MAPK_p38_MAPK14_ST	P06400	RB1	Q16539	MAPK14	S230	D224E	224	Missense	distal	-6	no	10.059	10.637	EPSD	ICGC;COSMIC	5.915	Up-regulation
CMGC_MAPK_p38_MAPK14_ST	P06400	RB1	Q16539	MAPK14	S249	R251L	251	Missense	proximal	2	no	10.723	10.379	EPSD;PhosphoSitePlus	ICGC	5.915	Down-regulation
CMGC_MAPK_p38_MAPK14_ST	P06400	RB1	Q16539	MAPK14	S249	G256C	256	Missense	distal	7	no	10.723	10.301	EPSD;PhosphoSitePlus	ICGC	5.915	Down-regulation
CMGC_MAPK_p38_MAPK14_ST	P06400	RB1	Q16539	MAPK14	T252	R251L	251	Missense	proximal	-1	no	9.952	10.337	PhosphoSitePlus;EPSD	ICGC	5.915	Up-regulation
CMGC_MAPK_p38_MAPK14_ST	P06400	RB1	Q16539	MAPK14	T252	G256C	256	Missense	distal	4	no	9.952	9.032	PhosphoSitePlus;EPSD	ICGC	5.915	Down-regulation
CMGC_MAPK_p38_MAPK14_ST	P06400	RB1	Q16539	MAPK14	S350	L343F	343	Missense	distal	-7	no	7.284	6.819	EPSD	ICGC;COSMIC	5.915	Down-regulation
CMGC_MAPK_p38_MAPK14_ST	P06400	RB1	Q16539	MAPK14	S350	Q354H	354	Missense	distal	4	no	7.284	7.095	EPSD	ICGC;COSMIC	5.915	Down-regulation
CMGC_MAPK_p38_MAPK14_ST	P06400	RB1	Q16539	MAPK14	T353	Q354H	354	Missense	proximal	1	no	7.218	0.772	EPSD	ICGC;COSMIC	5.915	Loss
CMGC_MAPK_p38_MAPK14_ST	P06400	RB1	Q16539	MAPK14	T356	Q354H	354	Missense	proximal	-2	no	12.525	11.274	EPSD	ICGC;COSMIC	5.915	Down-regulation
CMGC_MAPK_p38_MAPK14_ST	P06400	RB1	Q16539	MAPK14	S567	L572I	572	Missense	distal	5	no	7.930	7.785	EPSD;PhosphoSitePlus	ICGC;COSMIC	5.915	Down-regulation
CMGC_MAPK_p38_MAPK14_ST	P06400	RB1	Q16539	MAPK14	S567	D571Y	571	Missense	distal	4	no	7.930	8.053	EPSD;PhosphoSitePlus	ICGC	5.915	Up-regulation
CMGC_MAPK_p38_MAPK14_ST	P06400	RB1	Q16539	MAPK14	S567	W563L	563	Missense	distal	-4	no	7.930	7.890	EPSD;PhosphoSitePlus	ICGC	5.915	Down-regulation
CMGC_MAPK_p38_MAPK14_ST	P06400	RB1	Q16539	MAPK14	S567	A562P	562	Missense	distal	-5	no	7.930	8.266	EPSD;PhosphoSitePlus	ICGC;COSMIC;GDSC;CCLE	5.915	Up-regulation
CMGC_MAPK_p38_MAPK14_ST	P06400	RB1	Q16539	MAPK14	S567	L564F	564	Missense	distal	-3	no	7.930	6.954	EPSD;PhosphoSitePlus	ICGC	5.915	Down-regulation
CMGC_MAPK_p38_MAPK14_ST	P06400	RB1	Q16539	MAPK14	S780	P783L	783	Missense	distal	3	no	7.541	7.575	EPSD	ICGC	5.915	Up-regulation
CMGC_MAPK_p38_MAPK14_ST	P06400	RB1	Q16539	MAPK14	S788	P783L	783	Missense	distal	-5	no	8.319	8.600	EPSD	ICGC	5.915	Up-regulation
CMGC_MAPK_p38_MAPK14_ST	P06400	RB1	Q16539	MAPK14	S795	L797S	797	Missense	proximal	2	no	7.500	7.989	EPSD	ICGC;COSMIC	5.915	Up-regulation
CMGC_MAPK_p38_MAPK14_ST	P06400	RB1	Q16539	MAPK14	S795	G801E	801	Missense	distal	6	no	7.500	7.459	EPSD	ICGC	5.915	Down-regulation
CMGC_MAPK_p38_MAPK14_ST	P06400	RB1	Q16539	MAPK14	S807	G801E	801	Missense	distal	-6	no	12.132	12.443	EPSD	ICGC	5.915	Up-regulation
CMGC_MAPK_p38_MAPK14_ST	P40763	STAT3	Q16539	MAPK14	T12	R13W	13	Missense	proximal	1	no	4.501	6.467	EPSD	ICGC;COSMIC	5.915	Gain
CMGC_MAPK_p38_MAPK14_ST	P40763	STAT3	Q16539	MAPK14	S25	M28V	28	Missense	distal	3	no	7.291	7.296	EPSD	ICGC;COSMIC	5.915	Up-regulation
CMGC_MAPK_p38_MAPK14_ST	P40763	STAT3	Q16539	MAPK14	S25	R31W	31	Missense	distal	6	no	7.291	7.028	EPSD	ICGC;COSMIC	5.915	Down-regulation
CMGC_MAPK_p38_MAPK14_ST	P40763	STAT3	Q16539	MAPK14	S25	Y22H	22	Missense	distal	-3	no	7.291	6.945	EPSD	ICGC;COSMIC	5.915	Down-regulation
CMGC_MAPK_p38_MAPK14_ST	P40763	STAT3	Q16539	MAPK14	T440	L438P	438	Missense	proximal	-2	no	6.042	7.422	EPSD	ICGC;COSMIC	5.915	Up-regulation
CMGC_MAPK_p38_MAPK14_ST	P40763	STAT3	Q16539	MAPK14	T440	E442K	442	Missense	proximal	2	no	6.042	5.728	EPSD	ICGC	5.915	Loss
CMGC_MAPK_p38_MAPK14_ST	P40763	STAT3	Q16539	MAPK14	S691	P689T	689	Missense	proximal	-2	no	7.052	6.332	EPSD	ICGC	5.915	Down-regulation
CMGC_MAPK_p38_MAPK14_ST	P40763	STAT3	Q16539	MAPK14	S691	S691C	691	Missense	central	0	yes	7.052	0.000	EPSD	ICGC;COSMIC	5.915	Loss
CMGC_MAPK_p38_MAPK14_ST	P40763	STAT3	Q16539	MAPK14	S691	R688W	688	Missense	distal	-3	no	7.052	4.695	EPSD	ICGC;COSMIC;GDSC;CCLE	5.915	Loss
CMGC_MAPK_p38_MAPK14_ST	P40763	STAT3	Q16539	MAPK14	T714	T717N	717	Missense	distal	3	no	8.540	8.572	EPSD	ICGC	5.915	Up-regulation
CMGC_MAPK_p38_MAPK14_ST	P40763	STAT3	Q16539	MAPK14	T714	P715L	715	Missense	proximal	1	no	8.540	0.489	EPSD	ICGC	5.915	Loss
CMGC_MAPK_p38_MAPK14_ST	P40763	STAT3	Q16539	MAPK14	T714	P715Q	715	Missense	proximal	1	no	8.540	1.332	EPSD	ICGC;COSMIC	5.915	Loss
CMGC_MAPK_p38_MAPK14_ST	P40763	STAT3	Q16539	MAPK14	S727	L724P	724	Missense	distal	-3	no	13.540	14.507	PhosphoSitePlus	ICGC;COSMIC	5.915	Up-regulation
CMGC_MAPK_p38_MAPK14_ST	P40763	STAT3	Q16539	MAPK14	S727	S727P	727	Missense	central	0	yes	13.540	0.000	PhosphoSitePlus	ICGC	5.915	Loss
CMGC_MAPK_p38_MAPK14_ST	P40763	STAT3	Q16539	MAPK14	S727	L734S	734	Missense	distal	7	no	13.540	13.924	PhosphoSitePlus	ICGC;COSMIC	5.915	Up-regulation
CMGC_MAPK_p38_MAPK14_ST	O43684	BUB3	Q16539	MAPK14	T127	F134L	134	Missense	distal	7	no	12.145	12.630	EPSD	ICGC;COSMIC	5.915	Up-regulation
CMGC_MAPK_p38_MAPK14_ST	O43684	BUB3	Q16539	MAPK14	T127	P128H	128	Missense	proximal	1	no	12.145	-1.509	EPSD	ICGC	5.915	Loss
CMGC_MAPK_p38_MAPK14_ST	O43684	BUB3	Q16539	MAPK14	S211	K218N	218	Missense	distal	7	no	8.745	8.936	PhosphoSitePlus	ICGC	5.915	Up-regulation
CMGC_MAPK_p38_MAPK14_ST	O43684	BUB3	Q16539	MAPK14	S211	L208F	208	Missense	distal	-3	no	8.745	7.769	PhosphoSitePlus	ICGC	5.915	Down-regulation
CMGC_MAPK_p38_MAPK14_ST	P10415	BCL2	Q16539	MAPK14	T56	A60V	60	Missense	distal	4	no	9.545	9.111	PhosphoSitePlus;EPSD	ICGC;COSMIC;GDSC;CCLE	5.915	Down-regulation
CMGC_MAPK_p38_MAPK14_ST	P10415	BCL2	Q16539	MAPK14	T56	H58Q	58	Missense	proximal	2	no	9.545	9.501	PhosphoSitePlus;EPSD	ICGC;COSMIC	5.915	Down-regulation
CMGC_MAPK_p38_MAPK14_ST	P10415	BCL2	Q16539	MAPK14	T56	H58P	58	Missense	proximal	2	no	9.545	9.696	PhosphoSitePlus;EPSD	ICGC	5.915	Up-regulation
CMGC_MAPK_p38_MAPK14_ST	P10415	BCL2	Q16539	MAPK14	T56	P59A	59	Missense	distal	3	no	9.545	9.519	PhosphoSitePlus;EPSD	ICGC;COSMIC;GDSC;CCLE	5.915	Down-regulation
CMGC_MAPK_p38_MAPK14_ST	P10415	BCL2	Q16539	MAPK14	T56	S62F	62	Missense	distal	6	no	9.545	9.188	PhosphoSitePlus;EPSD	ICGC;COSMIC	5.915	Down-regulation
CMGC_MAPK_p38_MAPK14_ST	P10415	BCL2	Q16539	MAPK14	T56	P59S	59	Missense	distal	3	no	9.545	9.505	PhosphoSitePlus;EPSD	ICGC;COSMIC	5.915	Down-regulation
CMGC_MAPK_p38_MAPK14_ST	P10415	BCL2	Q16539	MAPK14	T56	P53S	53	Missense	distal	-3	no	9.545	10.309	PhosphoSitePlus;EPSD	ICGC;COSMIC	5.915	Up-regulation
CMGC_MAPK_p38_MAPK14_ST	P10415	BCL2	Q16539	MAPK14	T56	P59L	59	Missense	distal	3	no	9.545	9.579	PhosphoSitePlus;EPSD	ICGC;COSMIC;GDSC;CCLE	5.915	Up-regulation
CMGC_MAPK_p38_MAPK14_ST	P10415	BCL2	Q16539	MAPK14	T56	Q52R	52	Missense	distal	-4	no	9.545	9.177	PhosphoSitePlus;EPSD	ICGC;COSMIC	5.915	Down-regulation
CMGC_MAPK_p38_MAPK14_ST	P10415	BCL2	Q16539	MAPK14	T56	F49L	49	Missense	distal	-7	no	9.545	10.010	PhosphoSitePlus;EPSD	ICGC;COSMIC	5.915	Up-regulation
CMGC_MAPK_p38_MAPK14_ST	P10415	BCL2	Q16539	MAPK14	T56	A60T	60	Missense	distal	4	no	9.545	9.590	PhosphoSitePlus;EPSD	ICGC;COSMIC	5.915	Up-regulation
CMGC_MAPK_p38_MAPK14_ST	P10415	BCL2	Q16539	MAPK14	T56	T56M	56	Missense	central	0	yes	9.545	0.000	PhosphoSitePlus;EPSD	ICGC	5.915	Loss
CMGC_MAPK_p38_MAPK14_ST	P10415	BCL2	Q16539	MAPK14	T74	A81V	81	Missense	distal	7	no	9.176	9.067	EPSD	ICGC;COSMIC	5.915	Down-regulation
CMGC_MAPK_p38_MAPK14_ST	P10415	BCL2	Q16539	MAPK14	S87	P88Q	88	Missense	proximal	1	no	11.962	4.753	EPSD;PhosphoSitePlus	ICGC;COSMIC	5.915	Loss
CMGC_MAPK_p38_MAPK14_ST	P10415	BCL2	Q16539	MAPK14	S87	L86V	86	Missense	proximal	-1	no	11.962	11.900	EPSD;PhosphoSitePlus	ICGC;COSMIC;GDSC;CCLE	5.915	Down-regulation
CMGC_MAPK_p38_MAPK14_ST	P10415	BCL2	Q16539	MAPK14	S87	S87R	87	Missense	central	0	yes	11.962	0.000	EPSD;PhosphoSitePlus	ICGC;COSMIC	5.915	Loss
CMGC_MAPK_p38_MAPK14_ST	P10415	BCL2	Q16539	MAPK14	S87	A81V	81	Missense	distal	-6	no	11.962	11.474	EPSD;PhosphoSitePlus	ICGC;COSMIC	5.915	Down-regulation
CMGC_MAPK_p38_MAPK14_ST	P30279	CCND2	Q16539	MAPK14	T280	P281S	281	Missense	proximal	1	no	9.625	2.341	PhosphoSitePlus	ICGC;COSMIC	5.915	Loss
CMGC_MAPK_p38_MAPK14_ST	P30279	CCND2	Q16539	MAPK14	T280	V284E	284	Missense	distal	4	no	9.625	10.865	PhosphoSitePlus	ICGC;COSMIC	5.915	Up-regulation
CMGC_MAPK_p38_MAPK14_ST	P30279	CCND2	Q16539	MAPK14	T280	T280N	280	Missense	central	0	yes	9.625	0.000	PhosphoSitePlus	ICGC;COSMIC	5.915	Loss
CMGC_MAPK_p38_MAPK14_ST	P30279	CCND2	Q16539	MAPK14	T280	T280I	280	Missense	central	0	yes	9.625	0.000	PhosphoSitePlus	ICGC;COSMIC	5.915	Loss
CMGC_MAPK_p38_MAPK14_ST	P30279	CCND2	Q16539	MAPK14	T280	P281T	281	Missense	proximal	1	no	9.625	2.172	PhosphoSitePlus	ICGC;COSMIC	5.915	Loss
CMGC_MAPK_p38_MAPK14_ST	P30279	CCND2	Q16539	MAPK14	T280	P281R	281	Missense	proximal	1	no	9.625	1.690	PhosphoSitePlus	ICGC;COSMIC	5.915	Loss
CMGC_MAPK_p38_MAPK14_ST	P30279	CCND2	Q16539	MAPK14	T280	D276Y	276	Missense	distal	-4	no	9.625	9.128	PhosphoSitePlus	ICGC	5.915	Down-regulation
CMGC_MAPK_p38_MAPK14_ST	P30279	CCND2	Q16539	MAPK14	T280	V284L	284	Missense	distal	4	no	9.625	9.286	PhosphoSitePlus	ICGC;GDSC;CCLE	5.915	Down-regulation
CMGC_MAPK_p38_MAPK14_ST	P30279	CCND2	Q16539	MAPK14	T280	T280A	280	Missense	central	0	yes	9.625	0.000	PhosphoSitePlus	ICGC;COSMIC	5.915	Loss
CMGC_MAPK_p38_MAPK14_ST	P55273	CDKN2D	Q16539	MAPK14	S66	S73F	73	Missense	distal	7	no	11.408	10.538	PhosphoSitePlus	ICGC	5.915	Down-regulation
CMGC_MAPK_p38_MAPK14_ST	P55273	CDKN2D	Q16539	MAPK14	S76	V78F	78	Missense	proximal	2	no	7.827	7.589	EPSD	ICGC;COSMIC	5.915	Down-regulation
CMGC_MAPK_p38_MAPK14_ST	P55273	CDKN2D	Q16539	MAPK14	S76	S73F	73	Missense	distal	-3	no	7.827	5.120	EPSD	ICGC	5.915	Loss
CMGC_MAPK_p38_MAPK14_ST	P48436	SOX9	Q16539	MAPK14	S23	P22T	22	Missense	proximal	-1	no	12.129	12.153	EPSD	ICGC;COSMIC	5.915	Up-regulation
CMGC_MAPK_p38_MAPK14_ST	P48436	SOX9	Q16539	MAPK14	S33	C35F	35	Missense	proximal	2	no	11.945	11.692	EPSD	ICGC;COSMIC	5.915	Down-regulation
CMGC_MAPK_p38_MAPK14_ST	P48436	SOX9	Q16539	MAPK14	S211	A209V	209	Missense	proximal	-2	no	11.044	10.629	PhosphoSitePlus	ICGC;COSMIC	5.915	Down-regulation
CMGC_MAPK_p38_MAPK14_ST	P48436	SOX9	Q16539	MAPK14	S211	G217V	217	Missense	distal	6	no	11.044	10.682	PhosphoSitePlus	ICGC	5.915	Down-regulation
CMGC_MAPK_p38_MAPK14_ST	P48436	SOX9	Q16539	MAPK14	S214	A209V	209	Missense	distal	-5	no	7.938	8.430	EPSD	ICGC;COSMIC	5.915	Up-regulation
CMGC_MAPK_p38_MAPK14_ST	P48436	SOX9	Q16539	MAPK14	S214	G217V	217	Missense	distal	3	no	7.938	7.939	EPSD	ICGC	5.915	Up-regulation
CMGC_MAPK_p38_MAPK14_ST	P48436	SOX9	Q16539	MAPK14	S223	G217V	217	Missense	distal	-6	no	10.432	9.883	EPSD	ICGC	5.915	Down-regulation
CMGC_MAPK_p38_MAPK14_ST	P48436	SOX9	Q16539	MAPK14	S414	E409K	409	Missense	distal	-5	no	9.332	9.667	EPSD	ICGC;COSMIC	5.915	Up-regulation
CMGC_MAPK_p38_MAPK14_ST	Q8TE85	GRHL3	Q16539	MAPK14	S105	P102A	102	Missense	distal	-3	no	10.630	10.981	EPSD	ICGC;COSMIC	5.915	Up-regulation
CMGC_MAPK_p38_MAPK14_ST	Q8TE85	GRHL3	Q16539	MAPK14	S105	P102L	102	Missense	distal	-3	no	10.630	9.662	EPSD	ICGC;COSMIC	5.915	Down-regulation
CMGC_MAPK_p38_MAPK14_ST	Q8TE85	GRHL3	Q16539	MAPK14	S215	L212M	212	Missense	distal	-3	no	9.238	9.546	EPSD	ICGC;COSMIC	5.915	Up-regulation
CMGC_MAPK_p38_MAPK14_ST	Q8TE85	GRHL3	Q16539	MAPK14	T454	V457M	457	Missense	distal	3	no	7.761	7.757	PhosphoSitePlus	ICGC;COSMIC	5.915	Down-regulation
CMGC_MAPK_p38_MAPK14_ST	Q8TE85	GRHL3	Q16539	MAPK14	T454	T454M	454	Missense	central	0	yes	7.761	0.000	PhosphoSitePlus	ICGC	5.915	Loss
CMGC_MAPK_p38_MAPK14_ST	Q8TE85	GRHL3	Q16539	MAPK14	T454	R447W	447	Missense	distal	-7	no	7.761	7.022	PhosphoSitePlus	ICGC;COSMIC	5.915	Down-regulation
CMGC_MAPK_p38_MAPK14_ST	Q06330	RBPJ	Q16539	MAPK14	S7	P8L	8	Missense	proximal	1	no	13.829	5.778	EPSD	ICGC;COSMIC	5.915	Loss
CMGC_MAPK_p38_MAPK14_ST	Q06330	RBPJ	Q16539	MAPK14	S7	P12S	12	Missense	distal	5	no	13.829	14.280	EPSD	ICGC;COSMIC	5.915	Up-regulation
CMGC_MAPK_p38_MAPK14_ST	Q06330	RBPJ	Q16539	MAPK14	S18	P12S	12	Missense	distal	-6	no	9.580	10.187	EPSD	ICGC;COSMIC	5.915	Up-regulation
CMGC_MAPK_p38_MAPK14_ST	Q9C026	TRIM9	Q16539	MAPK14	T41	A34T	34	Missense	distal	-7	no	12.387	12.204	EPSD	ICGC;COSMIC	5.915	Down-regulation
CMGC_MAPK_p38_MAPK14_ST	Q9C026	TRIM9	Q16539	MAPK14	T41	Q40K	40	Missense	proximal	-1	no	12.387	12.380	EPSD	ICGC	5.915	Down-regulation
CMGC_MAPK_p38_MAPK14_ST	Q9C026	TRIM9	Q16539	MAPK14	T41	R35S	35	Missense	distal	-6	no	12.387	12.493	EPSD	ICGC	5.915	Up-regulation
CMGC_MAPK_p38_MAPK14_ST	Q9C026	TRIM9	Q16539	MAPK14	S46	R51W	51	Missense	distal	5	no	10.278	9.384	EPSD	ICGC	5.915	Down-regulation
CMGC_MAPK_p38_MAPK14_ST	Q9C026	TRIM9	Q16539	MAPK14	S46	H50N	50	Missense	distal	4	no	10.278	10.871	EPSD	ICGC	5.915	Up-regulation
CMGC_MAPK_p38_MAPK14_ST	Q9C026	TRIM9	Q16539	MAPK14	S46	Q40K	40	Missense	distal	-6	no	10.278	10.469	EPSD	ICGC	5.915	Up-regulation
CMGC_MAPK_p38_MAPK14_ST	Q9C026	TRIM9	Q16539	MAPK14	T406	T411M	411	Missense	distal	5	no	10.274	9.962	EPSD	ICGC;COSMIC	5.915	Down-regulation
CMGC_MAPK_p38_MAPK14_ST	Q9C026	TRIM9	Q16539	MAPK14	T406	P407L	407	Missense	proximal	1	no	10.274	2.224	EPSD	ICGC	5.915	Loss
CMGC_MAPK_p38_MAPK14_ST	Q9C026	TRIM9	Q16539	MAPK14	T406	W400L	400	Missense	distal	-6	no	10.274	10.478	EPSD	ICGC;COSMIC	5.915	Up-regulation
CMGC_MAPK_p38_MAPK14_ST	Q9C026	TRIM9	Q16539	MAPK14	S625	F627L	627	Missense	proximal	2	no	6.011	6.188	EPSD	ICGC;COSMIC	5.915	Up-regulation
CMGC_MAPK_p38_MAPK14_ST	Q9C026	TRIM9	Q16539	MAPK14	S625	S625L	625	Missense	central	0	yes	6.011	0.000	EPSD	ICGC;COSMIC	5.915	Loss
CMGC_MAPK_p38_MAPK14_ST	Q07817	BCL2L1	Q16539	MAPK14	S28	S23I	23	Missense	distal	-5	no	5.582	5.982	EPSD	ICGC	5.915	Gain
CMGC_MAPK_p38_MAPK14_ST	Q07817	BCL2L1	Q16539	MAPK14	S49	E44D	44	Missense	distal	-5	no	5.071	5.945	EPSD	ICGC;COSMIC	5.915	Gain
CMGC_MAPK_p38_MAPK14_ST	Q07817	BCL2L1	Q16539	MAPK14	S62	P63T	63	Missense	proximal	1	no	13.524	6.070	PhosphoSitePlus	ICGC	5.915	Down-regulation
CMGC_MAPK_p38_MAPK14_ST	Q07817	BCL2L1	Q16539	MAPK14	T115	S122R	122	Missense	distal	7	no	10.425	10.460	EPSD	ICGC	5.915	Up-regulation
CMGC_MAPK_p38_MAPK14_ST	Q07817	BCL2L1	Q16539	MAPK14	T115	T118K	118	Missense	distal	3	no	10.425	10.456	EPSD	ICGC	5.915	Up-regulation
CMGC_MAPK_p38_MAPK14_ST	Q07817	BCL2L1	Q16539	MAPK14	T115	T109K	109	Missense	distal	-6	no	10.425	10.113	EPSD	ICGC	5.915	Down-regulation
CMGC_MAPK_p38_MAPK14_ST	Q02156	PRKCE	Q16539	MAPK14	T228	G222W	222	Missense	distal	-6	no	9.657	8.714	EPSD	ICGC;COSMIC;GDSC;CCLE	5.915	Down-regulation
CMGC_MAPK_p38_MAPK14_ST	Q02156	PRKCE	Q16539	MAPK14	T228	P229L	229	Missense	proximal	1	no	9.657	1.606	EPSD	ICGC;COSMIC	5.915	Loss
CMGC_MAPK_p38_MAPK14_ST	Q02156	PRKCE	Q16539	MAPK14	T228	K225N	225	Missense	distal	-3	no	9.657	9.685	EPSD	ICGC;COSMIC	5.915	Up-regulation
CMGC_MAPK_p38_MAPK14_ST	Q02156	PRKCE	Q16539	MAPK14	T309	G307D	307	Missense	proximal	-2	no	8.689	7.938	EPSD	ICGC	5.915	Down-regulation
CMGC_MAPK_p38_MAPK14_ST	Q02156	PRKCE	Q16539	MAPK14	T309	V302L	302	Missense	distal	-7	no	8.689	9.113	EPSD	ICGC	5.915	Up-regulation
CMGC_MAPK_p38_MAPK14_ST	Q02156	PRKCE	Q16539	MAPK14	T309	N315S	315	Missense	distal	6	no	8.689	8.709	EPSD	ICGC;COSMIC	5.915	Up-regulation
CMGC_MAPK_p38_MAPK14_ST	Q02156	PRKCE	Q16539	MAPK14	S380	Q385H	385	Missense	distal	5	no	6.788	6.443	EPSD	ICGC;COSMIC	5.915	Down-regulation
CMGC_MAPK_p38_MAPK14_ST	Q02156	PRKCE	Q16539	MAPK14	S381	Q385H	385	Missense	distal	4	no	12.483	12.295	EPSD	ICGC;COSMIC	5.915	Down-regulation
CMGC_MAPK_p38_MAPK14_ST	Q02156	PRKCE	Q16539	MAPK14	S388	Q385H	385	Missense	distal	-3	no	11.577	11.603	EPSD	ICGC;COSMIC	5.915	Up-regulation
CMGC_MAPK_p38_MAPK14_ST	Q02156	PRKCE	Q16539	MAPK14	S388	E394K	394	Missense	distal	6	no	11.577	11.571	EPSD	ICGC;COSMIC;GDSC	5.915	Down-regulation
CMGC_MAPK_p38_MAPK14_ST	Q02156	PRKCE	Q16539	MAPK14	T566	V562A	562	Missense	distal	-4	no	6.524	6.241	EPSD	ICGC;COSMIC	5.915	Down-regulation
CMGC_MAPK_p38_MAPK14_ST	Q02156	PRKCE	Q16539	MAPK14	T566	F567L	567	Missense	proximal	1	no	6.524	4.477	EPSD	ICGC	5.915	Loss
CMGC_MAPK_p38_MAPK14_ST	Q02156	PRKCE	Q16539	MAPK14	T566	G569E	569	Missense	distal	3	no	6.524	6.478	EPSD	ICGC;COSMIC	5.915	Down-regulation
CMGC_MAPK_p38_MAPK14_ST	P23769	GATA2	Q16539	MAPK14	S73	R78H	78	Missense	distal	5	no	8.380	7.685	EPSD	ICGC	5.915	Down-regulation
CMGC_MAPK_p38_MAPK14_ST	P23769	GATA2	Q16539	MAPK14	S73	S73R	73	Missense	central	0	yes	8.380	0.000	EPSD	ICGC	5.915	Loss
CMGC_MAPK_p38_MAPK14_ST	P23769	GATA2	Q16539	MAPK14	S73	R67W	67	Missense	distal	-6	no	8.380	7.062	EPSD	ICGC;COSMIC	5.915	Down-regulation
CMGC_MAPK_p38_MAPK14_ST	P23769	GATA2	Q16539	MAPK14	S73	P74H	74	Missense	proximal	1	no	8.380	-5.274	EPSD	ICGC;COSMIC	5.915	Loss
CMGC_MAPK_p38_MAPK14_ST	P23769	GATA2	Q16539	MAPK14	S73	R78S	78	Missense	distal	5	no	8.380	8.690	EPSD	ICGC;COSMIC	5.915	Up-regulation
CMGC_MAPK_p38_MAPK14_ST	P23769	GATA2	Q16539	MAPK14	S119	V118M	118	Missense	proximal	-1	no	9.445	9.353	EPSD	ICGC	5.915	Down-regulation
CMGC_MAPK_p38_MAPK14_ST	P23769	GATA2	Q16539	MAPK14	S119	V118A	118	Missense	proximal	-1	no	9.445	9.289	EPSD	ICGC	5.915	Down-regulation
CMGC_MAPK_p38_MAPK14_ST	P23769	GATA2	Q16539	MAPK14	T176	T176M	176	Missense	central	0	yes	6.856	0.000	EPSD	ICGC;COSMIC	5.915	Loss
CMGC_MAPK_p38_MAPK14_ST	P23769	GATA2	Q16539	MAPK14	T176	P175S	175	Missense	proximal	-1	no	6.856	6.764	EPSD	ICGC	5.915	Down-regulation
CMGC_MAPK_p38_MAPK14_ST	P23769	GATA2	Q16539	MAPK14	T176	P183H	183	Missense	distal	7	no	6.856	6.579	EPSD	ICGC;COSMIC	5.915	Down-regulation
CMGC_MAPK_p38_MAPK14_ST	P23769	GATA2	Q16539	MAPK14	S182	T176M	176	Missense	distal	-6	no	10.864	10.277	EPSD	ICGC;COSMIC	5.915	Down-regulation
CMGC_MAPK_p38_MAPK14_ST	P23769	GATA2	Q16539	MAPK14	S182	P175S	175	Missense	distal	-7	no	10.864	10.952	EPSD	ICGC	5.915	Up-regulation
CMGC_MAPK_p38_MAPK14_ST	P23769	GATA2	Q16539	MAPK14	S182	P183H	183	Missense	proximal	1	no	10.864	-2.789	EPSD	ICGC;COSMIC	5.915	Loss
CMGC_MAPK_p38_MAPK14_ST	P23769	GATA2	Q16539	MAPK14	T188	P183H	183	Missense	distal	-5	no	6.852	7.166	EPSD	ICGC;COSMIC	5.915	Up-regulation
CMGC_MAPK_p38_MAPK14_ST	P23769	GATA2	Q16539	MAPK14	T303	R308W	308	Missense	distal	5	no	9.980	9.086	EPSD	ICGC	5.915	Down-regulation
CMGC_MAPK_p38_MAPK14_ST	P23769	GATA2	Q16539	MAPK14	T303	R308P	308	Missense	distal	5	no	9.980	9.839	EPSD	ICGC;COSMIC	5.915	Down-regulation
CMGC_MAPK_p38_MAPK14_ST	P23769	GATA2	Q16539	MAPK14	T303	L305F	305	Missense	proximal	2	no	9.980	9.803	EPSD	ICGC;COSMIC	5.915	Down-regulation
CMGC_MAPK_p38_MAPK14_ST	P23769	GATA2	Q16539	MAPK14	T303	G299W	299	Missense	distal	-4	no	9.980	10.622	EPSD	ICGC;COSMIC	5.915	Up-regulation
CMGC_MAPK_p38_MAPK14_ST	P02511	CRYAB	Q16539	MAPK14	S19	F17L	17	Missense	proximal	-2	no	10.811	10.644	EPSD	ICGC	5.915	Down-regulation
CMGC_MAPK_p38_MAPK14_ST	P02511	CRYAB	Q16539	MAPK14	S45	P39L	39	Missense	distal	-6	no	10.021	9.408	EPSD	ICGC	5.915	Down-regulation
CMGC_MAPK_p38_MAPK14_ST	P02511	CRYAB	Q16539	MAPK14	S45	P39Q	39	Missense	distal	-6	no	10.021	9.851	EPSD	ICGC;COSMIC	5.915	Down-regulation
CMGC_MAPK_p38_MAPK14_ST	P02511	CRYAB	Q16539	MAPK14	S59	T63N	63	Missense	distal	4	no	9.297	9.041	PhosphoSitePlus	ICGC	5.915	Down-regulation
CMGC_MAPK_p38_MAPK14_ST	P02511	CRYAB	Q16539	MAPK14	S85	P86Q	86	Missense	proximal	1	no	9.324	2.116	EPSD	ICGC	5.915	Loss
CMGC_MAPK_p38_MAPK14_ST	P02511	CRYAB	Q16539	MAPK14	T132	L137M	137	Missense	distal	5	no	6.224	6.692	EPSD	ICGC;COSMIC	5.915	Up-regulation
CMGC_MAPK_p38_MAPK14_ST	P02511	CRYAB	Q16539	MAPK14	T132	P130H	130	Missense	proximal	-2	no	6.224	3.957	EPSD	ICGC;COSMIC	5.915	Loss
CMGC_MAPK_p38_MAPK14_ST	Q15910	EZH2	Q16539	MAPK14	T339	R342P	342	Missense	distal	3	no	6.862	6.874	EPSD	ICGC;COSMIC	5.915	Up-regulation
CMGC_MAPK_p38_MAPK14_ST	Q15910	EZH2	Q16539	MAPK14	T345	P350S	350	Missense	distal	5	no	12.244	12.695	EPSD	ICGC;COSMIC	5.915	Up-regulation
CMGC_MAPK_p38_MAPK14_ST	Q15910	EZH2	Q16539	MAPK14	T345	R342P	342	Missense	distal	-3	no	12.244	10.968	EPSD	ICGC;COSMIC	5.915	Down-regulation
CMGC_MAPK_p38_MAPK14_ST	Q15910	EZH2	Q16539	MAPK14	T345	R349H	349	Missense	distal	4	no	12.244	11.851	EPSD	ICGC;COSMIC	5.915	Down-regulation
CMGC_MAPK_p38_MAPK14_ST	Q15910	EZH2	Q16539	MAPK14	T367	S362N	362	Missense	distal	-5	no	12.855	13.319	PhosphoSitePlus	ICGC;COSMIC	5.915	Up-regulation
CMGC_MAPK_p38_MAPK14_ST	Q15910	EZH2	Q16539	MAPK14	T416	P417S	417	Missense	proximal	1	no	10.218	2.934	EPSD	ICGC;COSMIC	5.915	Loss
CMGC_MAPK_p38_MAPK14_ST	P56817	BACE1	Q16539	MAPK14	S59	R57S	57	Missense	proximal	-2	no	6.121	6.320	EPSD	ICGC;COSMIC	5.915	Up-regulation
CMGC_MAPK_p38_MAPK14_ST	P56817	BACE1	Q16539	MAPK14	S59	D65E	65	Missense	distal	6	no	6.121	6.221	EPSD	ICGC	5.915	Up-regulation
CMGC_MAPK_p38_MAPK14_ST	P56817	BACE1	Q16539	MAPK14	S59	V61M	61	Missense	proximal	2	no	6.121	6.294	EPSD	ICGC;COSMIC	5.915	Up-regulation
CMGC_MAPK_p38_MAPK14_ST	P56817	BACE1	Q16539	MAPK14	S59	R57H	57	Missense	proximal	-2	no	6.121	4.543	EPSD	ICGC	5.915	Loss
CMGC_MAPK_p38_MAPK14_ST	P56817	BACE1	Q16539	MAPK14	S83	S83R	83	Missense	central	0	yes	9.038	0.000	PhosphoSitePlus	ICGC	5.915	Loss
CMGC_MAPK_p38_MAPK14_ST	P56817	BACE1	Q16539	MAPK14	S83	Q86E	86	Missense	distal	3	no	9.038	8.966	PhosphoSitePlus	ICGC;COSMIC	5.915	Down-regulation
CMGC_MAPK_p38_MAPK14_ST	P56817	BACE1	Q16539	MAPK14	S83	P85L	85	Missense	proximal	2	no	9.038	8.926	PhosphoSitePlus	ICGC;COSMIC	5.915	Down-regulation
CMGC_MAPK_p38_MAPK14_ST	P56817	BACE1	Q16539	MAPK14	S83	G82C	82	Missense	proximal	-1	no	9.038	8.981	PhosphoSitePlus	ICGC;COSMIC	5.915	Down-regulation
CMGC_MAPK_p38_MAPK14_ST	O15198	SMAD9	Q16539	MAPK14	T136	R132H	132	Missense	distal	-4	no	10.665	10.876	PhosphoSitePlus	ICGC;COSMIC	5.915	Up-regulation
CMGC_MAPK_p38_MAPK14_ST	O15198	SMAD9	Q16539	MAPK14	S458	K451R	451	Missense	distal	-7	no	8.843	8.578	EPSD	ICGC;COSMIC	5.915	Down-regulation
CMGC_MAPK_p38_MAPK14_ST	Q92945	KHSRP	Q16539	MAPK14	T100	T100N	100	Missense	central	0	yes	8.246	0.000	EPSD	ICGC	5.915	Loss
CMGC_MAPK_p38_MAPK14_ST	Q92945	KHSRP	Q16539	MAPK14	T100	N98K	98	Missense	proximal	-2	no	8.246	8.129	EPSD	ICGC	5.915	Down-regulation
CMGC_MAPK_p38_MAPK14_ST	Q92945	KHSRP	Q16539	MAPK14	T143	T146K	146	Missense	distal	3	no	6.478	6.509	EPSD	ICGC	5.915	Up-regulation
CMGC_MAPK_p38_MAPK14_ST	Q92945	KHSRP	Q16539	MAPK14	T143	T143N	143	Missense	central	0	yes	6.478	0.000	EPSD	ICGC	5.915	Loss
CMGC_MAPK_p38_MAPK14_ST	Q92945	KHSRP	Q16539	MAPK14	T143	E148D	148	Missense	distal	5	no	6.478	5.972	EPSD	ICGC	5.915	Down-regulation
CMGC_MAPK_p38_MAPK14_ST	Q92945	KHSRP	Q16539	MAPK14	T143	R150S	150	Missense	distal	7	no	6.478	6.444	EPSD	ICGC;COSMIC	5.915	Down-regulation
CMGC_MAPK_p38_MAPK14_ST	Q92945	KHSRP	Q16539	MAPK14	S181	G175A	175	Missense	distal	-6	no	9.083	9.021	EPSD	ICGC	5.915	Down-regulation
CMGC_MAPK_p38_MAPK14_ST	Q92945	KHSRP	Q16539	MAPK14	S181	P182Q	182	Missense	proximal	1	no	9.083	1.874	EPSD	ICGC;COSMIC	5.915	Loss
CMGC_MAPK_p38_MAPK14_ST	Q92945	KHSRP	Q16539	MAPK14	S480	F475L	475	Missense	distal	-5	no	9.381	9.325	EPSD	ICGC;COSMIC	5.915	Down-regulation
CMGC_MAPK_p38_MAPK14_ST	Q92945	KHSRP	Q16539	MAPK14	S480	R478L	478	Missense	proximal	-2	no	9.381	8.689	EPSD	ICGC;COSMIC	5.915	Down-regulation
CMGC_MAPK_p38_MAPK14_ST	Q92945	KHSRP	Q16539	MAPK14	T692	P698L	698	Missense	distal	6	no	12.764	12.625	PhosphoSitePlus	ICGC;COSMIC	5.915	Down-regulation
CMGC_MAPK_p38_MAPK14_ST	Q92945	KHSRP	Q16539	MAPK14	T692	Q685K	685	Missense	distal	-7	no	12.764	13.124	PhosphoSitePlus	ICGC	5.915	Up-regulation
CMGC_MAPK_p38_MAPK14_ST	P05198	EIF2S1	Q16539	MAPK14	S91	D84Y	84	Missense	distal	-7	no	9.525	9.395	EPSD	ICGC;COSMIC	5.915	Down-regulation
CMGC_MAPK_p38_MAPK14_ST	P05198	EIF2S1	Q16539	MAPK14	T185	R183H	183	Missense	proximal	-2	no	11.316	9.738	EPSD	ICGC;COSMIC	5.915	Down-regulation
CMGC_MAPK_p38_MAPK14_ST	P05198	EIF2S1	Q16539	MAPK14	T185	R182G	182	Missense	distal	-3	no	11.316	9.866	EPSD	ICGC	5.915	Down-regulation
CMGC_MAPK_p38_MAPK14_ST	P05198	EIF2S1	Q16539	MAPK14	T185	A188S	188	Missense	distal	3	no	11.316	11.302	EPSD	ICGC	5.915	Down-regulation
CMGC_MAPK_p38_MAPK14_ST	Q13309	SKP2	Q16539	MAPK14	S64	L70P	70	Missense	distal	6	no	9.493	9.632	PhosphoSitePlus	ICGC;COSMIC	5.915	Up-regulation
CMGC_MAPK_p38_MAPK14_ST	Q13309	SKP2	Q16539	MAPK14	S64	P62Q	62	Missense	proximal	-2	no	9.493	8.478	PhosphoSitePlus	ICGC;COSMIC	5.915	Down-regulation
CMGC_MAPK_p38_MAPK14_ST	Q13309	SKP2	Q16539	MAPK14	S179	F178L	178	Missense	proximal	-1	no	7.705	7.741	EPSD	ICGC;COSMIC	5.915	Up-regulation
CMGC_MAPK_p38_MAPK14_ST	Q13309	SKP2	Q16539	MAPK14	S179	H185R	185	Missense	distal	6	no	7.705	7.812	EPSD	ICGC;COSMIC	5.915	Up-regulation
CMGC_MAPK_p38_MAPK14_ST	Q9H3M7	TXNIP	Q16539	MAPK14	S249	S244L	244	Missense	distal	-5	no	5.457	6.187	EPSD	ICGC;COSMIC	5.915	Gain
CMGC_MAPK_p38_MAPK14_ST	Q9H3M7	TXNIP	Q16539	MAPK14	T306	S311N	311	Missense	distal	5	no	6.507	6.171	EPSD	ICGC	5.915	Down-regulation
CMGC_MAPK_p38_MAPK14_ST	Q9H3M7	TXNIP	Q16539	MAPK14	T306	R305S	305	Missense	proximal	-1	no	6.507	6.615	EPSD	ICGC;COSMIC	5.915	Up-regulation
CMGC_MAPK_p38_MAPK14_ST	Q9H3M7	TXNIP	Q16539	MAPK14	S307	S311N	311	Missense	distal	4	no	8.311	7.794	EPSD	ICGC	5.915	Down-regulation
CMGC_MAPK_p38_MAPK14_ST	Q9H3M7	TXNIP	Q16539	MAPK14	S307	R305S	305	Missense	proximal	-2	no	8.311	8.510	EPSD	ICGC;COSMIC	5.915	Up-regulation
CMGC_MAPK_p38_MAPK14_ST	Q9H3M7	TXNIP	Q16539	MAPK14	S311	S311N	311	Missense	central	0	yes	7.110	0.000	EPSD	ICGC	5.915	Loss
CMGC_MAPK_p38_MAPK14_ST	Q9H3M7	TXNIP	Q16539	MAPK14	S311	R305S	305	Missense	distal	-6	no	7.110	7.216	EPSD	ICGC;COSMIC	5.915	Up-regulation
CMGC_MAPK_p38_MAPK14_ST	Q9H3M7	TXNIP	Q16539	MAPK14	T349	D354Y	354	Missense	distal	5	no	10.803	11.068	EPSD	ICGC	5.915	Up-regulation
CMGC_MAPK_p38_MAPK14_ST	Q9H3M7	TXNIP	Q16539	MAPK14	T349	D354N	354	Missense	distal	5	no	10.803	11.012	EPSD	ICGC;COSMIC	5.915	Up-regulation
CMGC_MAPK_p38_MAPK14_ST	Q9H3M7	TXNIP	Q16539	MAPK14	S361	D354Y	354	Missense	distal	-7	no	10.642	10.513	PhosphoSitePlus	ICGC	5.915	Down-regulation
CMGC_MAPK_p38_MAPK14_ST	Q9H3M7	TXNIP	Q16539	MAPK14	S361	D354N	354	Missense	distal	-7	no	10.642	10.862	PhosphoSitePlus	ICGC;COSMIC	5.915	Up-regulation
CMGC_MAPK_p38_MAPK14_ST	P18850	ATF6	Q16539	MAPK14	S13	G6R	6	Missense	distal	-7	no	10.641	10.539	EPSD	ICGC;COSMIC	5.915	Down-regulation
CMGC_MAPK_p38_MAPK14_ST	P18850	ATF6	Q16539	MAPK14	S16	H21R	21	Missense	distal	5	no	10.902	11.597	EPSD	ICGC;COSMIC	5.915	Up-regulation
CMGC_MAPK_p38_MAPK14_ST	P18850	ATF6	Q16539	MAPK14	S94	L93R	93	Missense	proximal	-1	no	12.383	11.997	EPSD	ICGC;COSMIC	5.915	Down-regulation
CMGC_MAPK_p38_MAPK14_ST	P18850	ATF6	Q16539	MAPK14	S94	S97Y	97	Missense	distal	3	no	12.383	12.424	EPSD	ICGC	5.915	Up-regulation
CMGC_MAPK_p38_MAPK14_ST	P18850	ATF6	Q16539	MAPK14	S97	L93R	93	Missense	distal	-4	no	5.934	5.345	EPSD	ICGC;COSMIC	5.915	Loss
CMGC_MAPK_p38_MAPK14_ST	P18850	ATF6	Q16539	MAPK14	S97	S97Y	97	Missense	central	0	yes	5.934	0.000	EPSD	ICGC	5.915	Loss
CMGC_MAPK_p38_MAPK14_ST	P18850	ATF6	Q16539	MAPK14	S104	S110F	110	Missense	distal	6	no	10.523	10.166	EPSD	ICGC	5.915	Down-regulation
CMGC_MAPK_p38_MAPK14_ST	P18850	ATF6	Q16539	MAPK14	S104	R106Q	106	Missense	proximal	2	no	10.523	10.097	EPSD	ICGC;COSMIC	5.915	Down-regulation
CMGC_MAPK_p38_MAPK14_ST	P18850	ATF6	Q16539	MAPK14	S104	S97Y	97	Missense	distal	-7	no	10.523	9.963	EPSD	ICGC	5.915	Down-regulation
CMGC_MAPK_p38_MAPK14_ST	P18850	ATF6	Q16539	MAPK14	T166	K160N	160	Missense	distal	-6	no	8.902	9.064	PhosphoSitePlus	ICGC	5.915	Up-regulation
CMGC_MAPK_p38_MAPK14_ST	P18850	ATF6	Q16539	MAPK14	S373	R376Q	376	Missense	distal	3	no	10.127	10.168	EPSD	ICGC;COSMIC	5.915	Up-regulation
Other_NAK_BIKE_AAK1_ST	P49757	NUMB	Q2M2I8	AAK1	T102	D104E	104	Missense	proximal	2	no	11.455	11.460	PhosphoSitePlus	ICGC	2.491	Up-regulation
Other_NAK_BIKE_AAK1_ST	P49757	NUMB	Q2M2I8	AAK1	T102	L105F	105	Missense	distal	3	no	11.455	11.517	PhosphoSitePlus	ICGC	2.491	Up-regulation
Other_NAK_BIKE_AAK1_ST	P49757	NUMB	Q2M2I8	AAK1	T243	T250M	250	Missense	distal	7	no	2.906	2.929	EPSD	ICGC;COSMIC	2.491	Up-regulation
Other_NAK_BIKE_AAK1_ST	P49757	NUMB	Q2M2I8	AAK1	T246	T250M	250	Missense	distal	4	no	2.702	2.363	EPSD	ICGC;COSMIC	2.491	Loss
Other_NAK_BIKE_AAK1_ST	P49757	NUMB	Q2M2I8	AAK1	T251	M255I	255	Missense	distal	4	no	3.014	3.370	EPSD	ICGC;COSMIC	2.491	Up-regulation
Other_NAK_BIKE_AAK1_ST	P49757	NUMB	Q2M2I8	AAK1	T251	T250M	250	Missense	proximal	-1	no	3.014	3.045	EPSD	ICGC;COSMIC	2.491	Up-regulation
Other_NAK_BIKE_AAK1_ST	P49757	NUMB	Q2M2I8	AAK1	S284	L283I	283	Missense	proximal	-1	no	3.653	3.656	EPSD	ICGC;COSMIC	2.491	Up-regulation
Other_NAK_BIKE_AAK1_ST	Q96CW1	AP2M1	Q2M2I8	AAK1	T134	K139R	139	Missense	distal	5	no	2.496	2.425	EPSD	ICGC;COSMIC	2.491	Loss
Other_NAK_BIKE_AAK1_ST	Q96CW1	AP2M1	Q2M2I8	AAK1	T134	G137V	137	Missense	distal	3	no	2.496	2.580	EPSD	ICGC	2.491	Up-regulation
Other_NAK_BIKE_AAK1_ST	Q96CW1	AP2M1	Q2M2I8	AAK1	T134	Q136H	136	Missense	proximal	2	no	2.496	2.528	EPSD	ICGC	2.491	Up-regulation
Other_NAK_BIKE_AAK1_ST	Q96CW1	AP2M1	Q2M2I8	AAK1	T134	T134M	134	Missense	central	0	yes	2.496	0.000	EPSD	ICGC;COSMIC;GDSC;CCLE	2.491	Loss
Other_NAK_BIKE_AAK1_ST	Q96CW1	AP2M1	Q2M2I8	AAK1	T156	G160D	160	Missense	distal	4	no	9.991	9.737	PhosphoSitePlus	ICGC;COSMIC	2.491	Down-regulation
Other_NAK_BIKE_AAK1_ST	Q96CW1	AP2M1	Q2M2I8	AAK1	T156	G160V	160	Missense	distal	4	no	9.991	9.338	PhosphoSitePlus	ICGC;COSMIC	2.491	Down-regulation
Other_NAK_BIKE_AAK1_ST	Q96CW1	AP2M1	Q2M2I8	AAK1	T156	S149Y	149	Missense	distal	-7	no	9.991	9.985	PhosphoSitePlus	ICGC;COSMIC	2.491	Down-regulation
Other_NAK_BIKE_AAK1_ST	Q96CW1	AP2M1	Q2M2I8	AAK1	T233	D231Y	231	Missense	proximal	-2	no	3.105	3.103	EPSD	ICGC;COSMIC	2.491	Down-regulation
Other_NAK_BIKE_AAK1_ST	Q96CW1	AP2M1	Q2M2I8	AAK1	T247	D245N	245	Missense	proximal	-2	no	2.562	2.540	EPSD	ICGC;COSMIC	2.491	Down-regulation
TK_Fer_FES_Y	P07332	FES	P07332	FES	Y713	A709V	709	Missense	distal	-4	no	18.369	18.372	EPSD;PhosphoSitePlus	ICGC;COSMIC	7.476	Up-regulation
TK_Fer_FES_Y	P07332	FES	P07332	FES	Y713	S716A	716	Missense	distal	3	no	18.369	18.222	EPSD;PhosphoSitePlus	ICGC;COSMIC	7.476	Down-regulation
TK_Fer_FES_Y	P07332	FES	P07332	FES	Y811	R804Q	804	Missense	distal	-7	no	10.317	10.424	PhosphoSitePlus;EPSD	ICGC;COSMIC	7.476	Up-regulation
TK_Fer_FES_Y	P07332	FES	P07332	FES	Y811	R804W	804	Missense	distal	-7	no	10.317	10.261	PhosphoSitePlus;EPSD	ICGC;COSMIC	7.476	Down-regulation
TK_Fer_FES_Y	P07332	FES	P07332	FES	Y811	T809I	809	Missense	proximal	-2	no	10.317	10.044	PhosphoSitePlus;EPSD	ICGC;COSMIC	7.476	Down-regulation
TK_Fer_FES_Y	P11274	BCR	P07332	FES	Y177	F182L	182	Missense	distal	5	no	15.215	15.173	EPSD	ICGC;COSMIC	7.476	Down-regulation
TK_Fer_FES_Y	P11274	BCR	P07332	FES	Y231	R234H	234	Missense	distal	3	no	7.323	7.822	EPSD	ICGC	7.476	Gain
TK_Fer_FES_Y	P11274	BCR	P07332	FES	Y231	R234L	234	Missense	distal	3	no	7.323	7.726	EPSD	ICGC	7.476	Gain
TK_Fer_FES_Y	P11274	BCR	P07332	FES	Y231	A226V	226	Missense	distal	-5	no	7.323	7.829	EPSD	ICGC;COSMIC	7.476	Gain
TK_Fer_FES_Y	P11274	BCR	P07332	FES	Y231	A226T	226	Missense	distal	-5	no	7.323	7.870	EPSD	ICGC	7.476	Gain
TK_Fer_FES_Y	P11274	BCR	P07332	FES	Y276	Y276H	276	Missense	central	0	yes	14.785	0.000	EPSD	ICGC;COSMIC	7.476	Loss
TK_Fer_FES_Y	P11274	BCR	P07332	FES	Y276	L274M	274	Missense	proximal	-2	no	14.785	15.663	EPSD	ICGC;COSMIC	7.476	Up-regulation
TK_Fer_FES_Y	P11274	BCR	P07332	FES	Y279	Y276H	276	Missense	distal	-3	no	16.933	16.105	EPSD	ICGC;COSMIC	7.476	Down-regulation
TK_Fer_FES_Y	P11274	BCR	P07332	FES	Y279	L274M	274	Missense	distal	-5	no	16.933	16.523	EPSD	ICGC;COSMIC	7.476	Down-regulation
TK_Fer_FES_Y	P11274	BCR	P07332	FES	Y279	G285W	285	Missense	distal	6	no	16.933	17.059	EPSD	ICGC;COSMIC	7.476	Up-regulation
TK_Fer_FES_Y	P11274	BCR	P07332	FES	Y283	Y276H	276	Missense	distal	-7	no	15.668	15.598	EPSD	ICGC;COSMIC	7.476	Down-regulation
TK_Fer_FES_Y	P11274	BCR	P07332	FES	Y283	G285W	285	Missense	proximal	2	no	15.668	15.040	EPSD	ICGC;COSMIC	7.476	Down-regulation
TK_Fer_FES_Y	P11274	BCR	P07332	FES	Y328	G327D	327	Missense	proximal	-1	no	7.098	7.535	EPSD	ICGC;COSMIC	7.476	Gain
TK_Fer_FES_Y	P11274	BCR	P07332	FES	Y328	P330Q	330	Missense	proximal	2	no	7.098	7.531	EPSD	ICGC;COSMIC	7.476	Gain
TK_Fer_FES_Y	P11274	BCR	P07332	FES	Y360	R361S	361	Missense	proximal	1	no	6.715	8.467	EPSD	ICGC;COSMIC	7.476	Gain
Other_IKK_CHUK_ST	Q9Y6Q9	NCOA3	O15111	CHUK	S101	V100A	100	Missense	proximal	-1	no	189.644	188.675	EPSD	ICGC;COSMIC	187.474	Down-regulation
Other_IKK_CHUK_ST	Q9Y6Q9	NCOA3	O15111	CHUK	S101	Q105H	105	Missense	distal	4	no	189.644	183.059	EPSD	ICGC	187.474	Loss
Other_IKK_CHUK_ST	Q9Y6Q9	NCOA3	O15111	CHUK	S101	V100G	100	Missense	proximal	-1	no	189.644	188.747	EPSD	ICGC	187.474	Down-regulation
Other_IKK_CHUK_ST	Q9Y6Q9	NCOA3	O15111	CHUK	S214	D210N	210	Missense	distal	-4	no	199.228	218.887	EPSD	ICGC;COSMIC	187.474	Up-regulation
Other_IKK_CHUK_ST	Q9Y6Q9	NCOA3	O15111	CHUK	S288	D281Y	281	Missense	distal	-7	no	220.740	217.595	EPSD	ICGC;COSMIC	187.474	Down-regulation
Other_IKK_CHUK_ST	Q9Y6Q9	NCOA3	O15111	CHUK	S306	N308S	308	Missense	proximal	2	no	230.226	227.268	EPSD	ICGC;COSMIC	187.474	Down-regulation
Other_IKK_CHUK_ST	Q9Y6Q9	NCOA3	O15111	CHUK	S569	D576Y	576	Missense	distal	7	no	196.837	197.034	EPSD	ICGC;COSMIC	187.474	Up-regulation
Other_IKK_CHUK_ST	Q9Y6Q9	NCOA3	O15111	CHUK	S628	C627F	627	Missense	proximal	-1	no	190.274	189.928	EPSD	ICGC;COSMIC	187.474	Down-regulation
Other_IKK_CHUK_ST	Q9Y6Q9	NCOA3	O15111	CHUK	S628	S635F	635	Missense	distal	7	no	190.274	197.196	EPSD	ICGC	187.474	Up-regulation
Other_IKK_CHUK_ST	Q9Y6Q9	NCOA3	O15111	CHUK	S640	S635F	635	Missense	distal	-5	no	275.702	256.516	EPSD	ICGC	187.474	Down-regulation
Other_IKK_CHUK_ST	Q9Y6Q9	NCOA3	O15111	CHUK	S715	I713V	713	Missense	proximal	-2	no	202.517	201.810	EPSD	ICGC;COSMIC	187.474	Down-regulation
Other_IKK_CHUK_ST	Q9Y6Q9	NCOA3	O15111	CHUK	S715	T714A	714	Missense	proximal	-1	no	202.517	200.404	EPSD	ICGC	187.474	Down-regulation
Other_IKK_CHUK_ST	Q9Y6Q9	NCOA3	O15111	CHUK	S916	S917T	917	Missense	proximal	1	no	194.919	198.539	EPSD	ICGC;COSMIC	187.474	Up-regulation
Other_IKK_CHUK_ST	Q9Y6Q9	NCOA3	O15111	CHUK	S916	V911M	911	Missense	distal	-5	no	194.919	204.772	EPSD	ICGC;COSMIC	187.474	Up-regulation
Other_IKK_CHUK_ST	Q9Y6Q9	NCOA3	O15111	CHUK	S1033	S1033Y	1033	Missense	central	0	yes	230.885	0.000	EPSD	ICGC;COSMIC	187.474	Loss
Other_IKK_CHUK_ST	Q9Y6Q9	NCOA3	O15111	CHUK	S1330	A1324S	1324	Missense	distal	-6	no	194.924	191.793	EPSD	ICGC	187.474	Down-regulation
Other_IKK_CHUK_ST	Q9Y6Q9	NCOA3	O15111	CHUK	S1338	P1342L	1342	Missense	distal	4	no	202.883	203.674	EPSD	ICGC;COSMIC	187.474	Up-regulation
Other_IKK_CHUK_ST	P19838	NFKB1	O15111	CHUK	S74	S74I	74	Missense	central	0	yes	243.762	0.000	EPSD	ICGC	187.474	Loss
Other_IKK_CHUK_ST	P19838	NFKB1	O15111	CHUK	S74	G67C	67	Missense	distal	-7	no	243.762	239.226	EPSD	ICGC	187.474	Down-regulation
Other_IKK_CHUK_ST	P19838	NFKB1	O15111	CHUK	S74	G71C	71	Missense	distal	-3	no	243.762	238.657	EPSD	ICGC;COSMIC	187.474	Down-regulation
Other_IKK_CHUK_ST	P19838	NFKB1	O15111	CHUK	S74	K78N	78	Missense	distal	4	no	243.762	242.440	EPSD	ICGC;COSMIC	187.474	Down-regulation
Other_IKK_CHUK_ST	P19838	NFKB1	O15111	CHUK	S301	T303R	303	Missense	proximal	2	no	190.288	191.594	EPSD	ICGC;COSMIC	187.474	Up-regulation
Other_IKK_CHUK_ST	P19838	NFKB1	O15111	CHUK	S301	P302S	302	Missense	proximal	1	no	190.288	184.886	EPSD	ICGC	187.474	Loss
Other_IKK_CHUK_ST	P19838	NFKB1	O15111	CHUK	S301	P302H	302	Missense	proximal	1	no	190.288	177.698	EPSD	ICGC;COSMIC	187.474	Loss
Other_IKK_CHUK_ST	P19838	NFKB1	O15111	CHUK	S301	R307I	307	Missense	distal	6	no	190.288	188.407	EPSD	ICGC;COSMIC	187.474	Down-regulation
Other_IKK_CHUK_ST	P19838	NFKB1	O15111	CHUK	S373	S371L	371	Missense	proximal	-2	no	212.594	224.135	EPSD	ICGC;COSMIC	187.474	Up-regulation
Other_IKK_CHUK_ST	P19838	NFKB1	O15111	CHUK	S373	G377S	377	Missense	distal	4	no	212.594	220.988	EPSD	ICGC;GDSC	187.474	Up-regulation
Other_IKK_CHUK_ST	P19838	NFKB1	O15111	CHUK	S373	N369K	369	Missense	distal	-4	no	212.594	201.243	EPSD	ICGC;COSMIC	187.474	Down-regulation
Other_IKK_CHUK_ST	P19838	NFKB1	O15111	CHUK	S373	L366P	366	Missense	distal	-7	no	212.594	212.031	EPSD	ICGC;COSMIC	187.474	Down-regulation
Other_IKK_CHUK_ST	P19838	NFKB1	O15111	CHUK	S373	P368S	368	Missense	distal	-5	no	212.594	221.247	EPSD	ICGC;COSMIC	187.474	Up-regulation
Other_IKK_CHUK_ST	P19838	NFKB1	O15111	CHUK	S855	Y862C	862	Missense	distal	7	no	196.495	201.686	EPSD	ICGC;COSMIC	187.474	Up-regulation
Other_IKK_CHUK_ST	P19838	NFKB1	O15111	CHUK	S855	F848L	848	Missense	distal	-7	no	196.495	197.345	EPSD	ICGC;COSMIC	187.474	Up-regulation
Other_IKK_CHUK_ST	P19838	NFKB1	O15111	CHUK	S855	P854S	854	Missense	proximal	-1	no	196.495	197.556	EPSD	ICGC;CCLE	187.474	Up-regulation
Other_IKK_CHUK_ST	P19838	NFKB1	O15111	CHUK	T857	Y862C	862	Missense	distal	5	no	198.004	203.668	EPSD	ICGC;COSMIC	187.474	Up-regulation
Other_IKK_CHUK_ST	P19838	NFKB1	O15111	CHUK	T857	P854S	854	Missense	distal	-3	no	198.004	184.136	EPSD	ICGC;CCLE	187.474	Loss
Other_IKK_CHUK_ST	P19838	NFKB1	O15111	CHUK	S865	Y862C	862	Missense	distal	-3	no	221.584	224.601	EPSD	ICGC;COSMIC	187.474	Up-regulation
Other_IKK_CHUK_ST	P19838	NFKB1	O15111	CHUK	S899	Q900E	900	Missense	proximal	1	no	185.834	196.122	EPSD	ICGC;COSMIC	187.474	Gain
Other_IKK_CHUK_ST	P19838	NFKB1	O15111	CHUK	S899	A901D	901	Missense	proximal	2	no	185.834	188.380	EPSD	ICGC;COSMIC	187.474	Gain
Other_IKK_CHUK_ST	P19838	NFKB1	O15111	CHUK	S903	Q900E	900	Missense	distal	-3	no	199.900	211.675	EPSD	ICGC;COSMIC	187.474	Up-regulation
Other_IKK_CHUK_ST	P19838	NFKB1	O15111	CHUK	S903	A901D	901	Missense	proximal	-2	no	199.900	166.830	EPSD	ICGC;COSMIC	187.474	Loss
Other_IKK_CHUK_ST	P19838	NFKB1	O15111	CHUK	S903	S907L	907	Missense	distal	4	no	199.900	198.761	EPSD	ICGC;COSMIC	187.474	Down-regulation
Other_IKK_CHUK_ST	P19838	NFKB1	O15111	CHUK	S903	P908H	908	Missense	distal	5	no	199.900	200.116	EPSD	ICGC;COSMIC	187.474	Up-regulation
Other_IKK_CHUK_ST	P19838	NFKB1	O15111	CHUK	S923	S921I	921	Missense	proximal	-2	no	239.182	247.475	PhosphoSitePlus;EPSD	ICGC;COSMIC	187.474	Up-regulation
Other_IKK_CHUK_ST	P19838	NFKB1	O15111	CHUK	S923	D926N	926	Missense	distal	3	no	239.182	202.221	PhosphoSitePlus;EPSD	ICGC;COSMIC	187.474	Down-regulation
Other_IKK_CHUK_ST	P19838	NFKB1	O15111	CHUK	S927	R934L	934	Missense	distal	7	no	231.963	221.401	EPSD;PhosphoSitePlus	ICGC	187.474	Down-regulation
Other_IKK_CHUK_ST	P19838	NFKB1	O15111	CHUK	S927	S921I	921	Missense	distal	-6	no	231.963	234.575	EPSD;PhosphoSitePlus	ICGC;COSMIC	187.474	Up-regulation
Other_IKK_CHUK_ST	P19838	NFKB1	O15111	CHUK	S927	R934C	934	Missense	distal	7	no	231.963	230.186	EPSD;PhosphoSitePlus	ICGC;COSMIC	187.474	Down-regulation
Other_IKK_CHUK_ST	P19838	NFKB1	O15111	CHUK	S927	D926N	926	Missense	proximal	-1	no	231.963	229.063	EPSD;PhosphoSitePlus	ICGC;COSMIC	187.474	Down-regulation
Other_IKK_CHUK_ST	P19838	NFKB1	O15111	CHUK	S932	R934L	934	Missense	proximal	2	no	220.499	218.805	EPSD;PhosphoSitePlus	ICGC	187.474	Down-regulation
Other_IKK_CHUK_ST	P19838	NFKB1	O15111	CHUK	S932	R934C	934	Missense	proximal	2	no	220.499	223.182	EPSD;PhosphoSitePlus	ICGC;COSMIC	187.474	Up-regulation
Other_IKK_CHUK_ST	P19838	NFKB1	O15111	CHUK	S932	D926N	926	Missense	distal	-6	no	220.499	225.375	EPSD;PhosphoSitePlus	ICGC;COSMIC	187.474	Up-regulation
Other_IKK_CHUK_ST	P19838	NFKB1	O15111	CHUK	S937	S944R	944	Missense	distal	7	no	181.834	193.532	EPSD	ICGC	187.474	Gain
Other_IKK_CHUK_ST	P19838	NFKB1	O15111	CHUK	S941	R934L	934	Missense	distal	-7	no	219.876	221.795	EPSD	ICGC	187.474	Up-regulation
Other_IKK_CHUK_ST	P19838	NFKB1	O15111	CHUK	S941	A946V	946	Missense	distal	5	no	219.876	223.784	EPSD	ICGC	187.474	Up-regulation
Other_IKK_CHUK_ST	P19838	NFKB1	O15111	CHUK	S941	S944R	944	Missense	distal	3	no	219.876	181.351	EPSD	ICGC	187.474	Loss
Other_IKK_CHUK_ST	P19838	NFKB1	O15111	CHUK	S941	R934C	934	Missense	distal	-7	no	219.876	219.193	EPSD	ICGC;COSMIC	187.474	Down-regulation
Other_IKK_CHUK_ST	P03372	ESR1	O15111	CHUK	S118	H112P	112	Missense	distal	-6	no	231.360	229.639	PhosphoSitePlus	ICGC;COSMIC	187.474	Down-regulation
Other_IKK_CHUK_ST	P03372	ESR1	O15111	CHUK	S118	P114L	114	Missense	distal	-4	no	231.360	203.127	PhosphoSitePlus	ICGC;COSMIC	187.474	Down-regulation
Other_IKK_CHUK_ST	P03372	ESR1	O15111	CHUK	S167	E163Q	163	Missense	distal	-4	no	203.246	209.461	EPSD	ICGC;COSMIC	187.474	Up-regulation
Other_IKK_CHUK_ST	P03372	ESR1	O15111	CHUK	S201	G204C	204	Missense	distal	3	no	213.048	167.841	EPSD	ICGC	187.474	Loss
Other_IKK_CHUK_ST	P03372	ESR1	O15111	CHUK	S201	C205Y	205	Missense	distal	4	no	213.048	215.994	EPSD	ICGC;COSMIC	187.474	Up-regulation
Other_IKK_CHUK_ST	P03372	ESR1	O15111	CHUK	S341	S341L	341	Missense	central	0	yes	209.841	0.000	EPSD	ICGC;COSMIC;GDSC;CCLE	187.474	Loss
Other_IKK_CHUK_ST	P03372	ESR1	O15111	CHUK	S341	P336A	336	Missense	distal	-5	no	209.841	203.234	EPSD	ICGC;COSMIC	187.474	Down-regulation
Other_IKK_CHUK_ST	P03372	ESR1	O15111	CHUK	S573	S576L	576	Missense	distal	3	no	190.752	187.982	EPSD	ICGC;COSMIC	187.474	Down-regulation
Other_IKK_CHUK_ST	P03372	ESR1	O15111	CHUK	S575	S576L	576	Missense	proximal	1	no	204.263	223.737	EPSD	ICGC;COSMIC	187.474	Up-regulation
Other_IKK_CHUK_ST	P03372	ESR1	O15111	CHUK	S578	S576L	576	Missense	proximal	-2	no	220.288	231.829	EPSD	ICGC;COSMIC	187.474	Up-regulation
Other_IKK_CHUK_ST	P25963	NFKBIA	O15111	CHUK	S32	R29S	29	Missense	distal	-3	no	241.183	222.205	EPSD;PhosphoSitePlus	ICGC	187.474	Down-regulation
Other_IKK_CHUK_ST	P25963	NFKBIA	O15111	CHUK	S32	D31G	31	Missense	proximal	-1	no	241.183	237.432	EPSD;PhosphoSitePlus	ICGC;COSMIC	187.474	Down-regulation
Other_IKK_CHUK_ST	P25963	NFKBIA	O15111	CHUK	S32	K38T	38	Missense	distal	6	no	241.183	231.814	EPSD;PhosphoSitePlus	ICGC	187.474	Down-regulation
Other_IKK_CHUK_ST	P25963	NFKBIA	O15111	CHUK	S36	R29S	29	Missense	distal	-7	no	284.901	289.792	PhosphoSitePlus;EPSD	ICGC	187.474	Up-regulation
Other_IKK_CHUK_ST	P25963	NFKBIA	O15111	CHUK	S36	D31G	31	Missense	distal	-5	no	284.901	264.302	PhosphoSitePlus;EPSD	ICGC;COSMIC	187.474	Down-regulation
Other_IKK_CHUK_ST	P25963	NFKBIA	O15111	CHUK	S36	K38T	38	Missense	proximal	2	no	284.901	283.577	PhosphoSitePlus;EPSD	ICGC	187.474	Down-regulation
Other_IKK_CHUK_ST	Q00653	NFKB2	O15111	CHUK	S99	D94N	94	Missense	distal	-5	no	219.724	201.676	EPSD;PhosphoSitePlus	ICGC;COSMIC	187.474	Down-regulation
Other_IKK_CHUK_ST	Q00653	NFKB2	O15111	CHUK	S115	L117M	117	Missense	proximal	2	no	232.404	234.740	EPSD;PhosphoSitePlus	ICGC	187.474	Up-regulation
Other_IKK_CHUK_ST	Q00653	NFKB2	O15111	CHUK	S115	V122I	122	Missense	distal	7	no	232.404	221.559	EPSD;PhosphoSitePlus	ICGC;COSMIC	187.474	Down-regulation
Other_IKK_CHUK_ST	Q00653	NFKB2	O15111	CHUK	S115	A121D	121	Missense	distal	6	no	232.404	232.518	EPSD;PhosphoSitePlus	ICGC;COSMIC	187.474	Up-regulation
Other_IKK_CHUK_ST	Q00653	NFKB2	O15111	CHUK	S123	L117M	117	Missense	distal	-6	no	233.539	238.808	EPSD;PhosphoSitePlus	ICGC	187.474	Up-regulation
Other_IKK_CHUK_ST	Q00653	NFKB2	O15111	CHUK	S123	V122I	122	Missense	proximal	-1	no	233.539	232.396	EPSD;PhosphoSitePlus	ICGC;COSMIC	187.474	Down-regulation
Other_IKK_CHUK_ST	Q00653	NFKB2	O15111	CHUK	S123	A121D	121	Missense	proximal	-2	no	233.539	200.469	EPSD;PhosphoSitePlus	ICGC;COSMIC	187.474	Down-regulation
Other_IKK_CHUK_ST	Q00653	NFKB2	O15111	CHUK	S231	R232L	232	Missense	proximal	1	no	210.317	236.068	EPSD	ICGC;COSMIC	187.474	Up-regulation
Other_IKK_CHUK_ST	Q00653	NFKB2	O15111	CHUK	S239	R232L	232	Missense	distal	-7	no	243.078	244.997	EPSD	ICGC;COSMIC	187.474	Up-regulation
Other_IKK_CHUK_ST	Q00653	NFKB2	O15111	CHUK	S427	R428S	428	Missense	proximal	1	no	194.354	200.630	EPSD	ICGC;COSMIC	187.474	Up-regulation
Other_IKK_CHUK_ST	Q00653	NFKB2	O15111	CHUK	S713	G719E	719	Missense	distal	6	no	185.701	193.187	EPSD	ICGC	187.474	Gain
Other_IKK_CHUK_ST	Q00653	NFKB2	O15111	CHUK	S717	G719E	719	Missense	proximal	2	no	199.018	196.786	EPSD	ICGC	187.474	Down-regulation
Other_IKK_CHUK_ST	Q00653	NFKB2	O15111	CHUK	S717	S715L	715	Missense	proximal	-2	no	199.018	210.559	EPSD	ICGC	187.474	Up-regulation
Other_IKK_CHUK_ST	Q00653	NFKB2	O15111	CHUK	S717	D723N	723	Missense	distal	6	no	199.018	202.936	EPSD	ICGC;COSMIC;GDSC	187.474	Up-regulation
Other_IKK_CHUK_ST	Q00653	NFKB2	O15111	CHUK	S727	D723N	723	Missense	distal	-4	no	173.658	193.317	EPSD	ICGC;COSMIC;GDSC	187.474	Gain
Other_IKK_CHUK_ST	Q00653	NFKB2	O15111	CHUK	S769	P766Q	766	Missense	distal	-3	no	217.882	197.062	EPSD	ICGC;COSMIC	187.474	Down-regulation
Other_IKK_CHUK_ST	Q00653	NFKB2	O15111	CHUK	S769	P766L	766	Missense	distal	-3	no	217.882	207.778	EPSD	ICGC;COSMIC	187.474	Down-regulation
Other_IKK_CHUK_ST	Q00653	NFKB2	O15111	CHUK	S812	T806K	806	Missense	distal	-6	no	194.115	199.868	EPSD	ICGC;COSMIC	187.474	Up-regulation
Other_IKK_CHUK_ST	Q00653	NFKB2	O15111	CHUK	S812	R808Q	808	Missense	distal	-4	no	194.115	199.575	EPSD	ICGC	187.474	Up-regulation
Other_IKK_CHUK_ST	Q00653	NFKB2	O15111	CHUK	S814	R808Q	808	Missense	distal	-6	no	200.595	194.806	EPSD	ICGC	187.474	Down-regulation
Other_IKK_CHUK_ST	Q01201	RELB	O15111	CHUK	S42	V47F	47	Missense	distal	5	no	204.700	207.015	EPSD	ICGC;COSMIC	187.474	Up-regulation
Other_IKK_CHUK_ST	Q01201	RELB	O15111	CHUK	S48	V47F	47	Missense	proximal	-1	no	188.722	188.211	EPSD	ICGC;COSMIC	187.474	Down-regulation
Other_IKK_CHUK_ST	Q676U5	ATG16L1	O15111	CHUK	S278	G284C	284	Missense	distal	6	no	257.874	266.152	PhosphoSitePlus	ICGC;COSMIC	187.474	Up-regulation
Other_IKK_CHUK_ST	Q676U5	ATG16L1	O15111	CHUK	S278	A272V	272	Missense	distal	-6	no	257.874	256.357	PhosphoSitePlus	ICGC;COSMIC	187.474	Down-regulation
Other_IKK_CHUK_ST	Q676U5	ATG16L1	O15111	CHUK	S278	S278F	278	Missense	central	0	yes	257.874	0.000	PhosphoSitePlus	ICGC;COSMIC;GDSC	187.474	Loss
Other_IKK_CHUK_ST	Q676U5	ATG16L1	O15111	CHUK	S287	R286L	286	Missense	proximal	-1	no	186.604	189.154	EPSD	ICGC	187.474	Gain
Other_IKK_CHUK_ST	P35222	CTNNB1	O15111	CHUK	S246	L252H	252	Missense	distal	6	no	216.740	221.989	EPSD	ICGC;COSMIC	187.474	Up-regulation
Other_IKK_CHUK_ST	P35222	CTNNB1	O15111	CHUK	S715	R710H	710	Missense	distal	-5	no	200.492	205.377	EPSD	ICGC;COSMIC	187.474	Up-regulation
Other_IKK_CHUK_ST	Q9C0C7	AMBRA1	O15111	CHUK	S948	M952L	952	Missense	distal	4	no	219.257	222.289	EPSD	ICGC;COSMIC	187.474	Up-regulation
Other_IKK_CHUK_ST	Q9C0C7	AMBRA1	O15111	CHUK	S948	M952V	952	Missense	distal	4	no	219.257	222.150	EPSD	ICGC;COSMIC	187.474	Up-regulation
Other_IKK_CHUK_ST	Q92793	CREBBP	O15111	CHUK	S23	F30V	30	Missense	distal	7	no	243.424	248.734	EPSD	ICGC;COSMIC	187.474	Up-regulation
Other_IKK_CHUK_ST	Q92793	CREBBP	O15111	CHUK	S381	N374K	374	Missense	distal	-7	no	194.254	192.971	EPSD	ICGC	187.474	Down-regulation
Other_IKK_CHUK_ST	Q92793	CREBBP	O15111	CHUK	S750	Q752K	752	Missense	proximal	2	no	208.417	211.103	EPSD	ICGC;COSMIC	187.474	Up-regulation
Other_IKK_CHUK_ST	Q92793	CREBBP	O15111	CHUK	S1043	E1050G	1050	Missense	distal	7	no	184.096	191.818	EPSD	ICGC	187.474	Gain
Other_IKK_CHUK_ST	P42345	MTOR	O15111	CHUK	S31	K30T	30	Missense	proximal	-1	no	196.279	197.056	EPSD	ICGC;COSMIC	187.474	Up-regulation
Other_IKK_CHUK_ST	P42345	MTOR	O15111	CHUK	S581	D578N	578	Missense	distal	-3	no	221.298	219.649	EPSD	ICGC	187.474	Down-regulation
Other_IKK_CHUK_ST	P42345	MTOR	O15111	CHUK	S1145	F1148L	1148	Missense	distal	3	no	165.713	197.202	EPSD	ICGC	187.474	Gain
Other_IKK_CHUK_ST	P42345	MTOR	O15111	CHUK	S1171	S1166R	1166	Missense	distal	-5	no	191.963	175.585	EPSD	ICGC;COSMIC	187.474	Loss
Other_IKK_CHUK_ST	P42345	MTOR	O15111	CHUK	S1171	A1173G	1173	Missense	proximal	2	no	191.963	196.008	EPSD	ICGC;COSMIC	187.474	Up-regulation
Other_IKK_CHUK_ST	P42345	MTOR	O15111	CHUK	S1299	C1303F	1303	Missense	distal	4	no	182.904	189.457	EPSD	ICGC;COSMIC	187.474	Gain
Other_IKK_CHUK_ST	P42345	MTOR	O15111	CHUK	S1299	C1303R	1303	Missense	distal	4	no	182.904	189.590	EPSD	ICGC;COSMIC	187.474	Gain
Other_IKK_CHUK_ST	P42345	MTOR	O15111	CHUK	S1415	P1408T	1408	Missense	distal	-7	no	232.439	233.349	PhosphoSitePlus	ICGC;COSMIC	187.474	Up-regulation
Other_IKK_CHUK_ST	P42345	MTOR	O15111	CHUK	S1982	T1985K	1985	Missense	distal	3	no	195.338	193.809	EPSD	ICGC;COSMIC	187.474	Down-regulation
Other_IKK_CHUK_ST	P42345	MTOR	O15111	CHUK	T2173	L2174I	2174	Missense	proximal	1	no	187.539	179.899	EPSD	ICGC	187.474	Loss
Other_IKK_CHUK_ST	P42345	MTOR	O15111	CHUK	T2173	G2176D	2176	Missense	distal	3	no	187.539	215.279	EPSD	ICGC;COSMIC	187.474	Up-regulation
Other_IKK_CHUK_ST	Q9Y618	NCOR2	O15111	CHUK	T11	W12L	12	Missense	proximal	1	no	175.797	187.636	EPSD	ICGC;COSMIC	187.474	Gain
Other_IKK_CHUK_ST	Q9Y618	NCOR2	O15111	CHUK	S132	R139H	139	Missense	distal	7	no	213.348	209.985	EPSD	ICGC;COSMIC;GDSC;CCLE	187.474	Down-regulation
Other_IKK_CHUK_ST	Q9Y618	NCOR2	O15111	CHUK	S132	P129H	129	Missense	distal	-3	no	213.348	205.768	EPSD	ICGC	187.474	Down-regulation
Other_IKK_CHUK_ST	Q9Y618	NCOR2	O15111	CHUK	S132	T136N	136	Missense	distal	4	no	213.348	215.158	EPSD	ICGC	187.474	Up-regulation
Other_IKK_CHUK_ST	Q9Y618	NCOR2	O15111	CHUK	S140	T136N	136	Missense	distal	-4	no	178.092	198.573	EPSD	ICGC	187.474	Gain
Other_IKK_CHUK_ST	Q9Y618	NCOR2	O15111	CHUK	S1118	S1119L	1119	Missense	proximal	1	no	264.378	283.853	EPSD	ICGC	187.474	Up-regulation
Other_IKK_CHUK_ST	Q9Y618	NCOR2	O15111	CHUK	S2221	E2216D	2216	Missense	distal	-5	no	164.799	190.000	EPSD	ICGC;COSMIC	187.474	Gain
Other_IKK_CHUK_ST	Q04206	RELA	O15111	CHUK	T136	R133C	133	Missense	distal	-3	no	192.720	182.645	EPSD	ICGC	187.474	Loss
Other_IKK_CHUK_ST	Q04206	RELA	O15111	CHUK	S238	A235S	235	Missense	distal	-3	no	190.680	183.420	EPSD	ICGC;COSMIC	187.474	Loss
Other_IKK_CHUK_ST	Q04206	RELA	O15111	CHUK	S238	R236Q	236	Missense	proximal	-2	no	190.680	199.424	EPSD	ICGC;COSMIC	187.474	Up-regulation
Other_IKK_CHUK_ST	Q04206	RELA	O15111	CHUK	S238	E234V	234	Missense	distal	-4	no	190.680	189.673	EPSD	ICGC	187.474	Down-regulation
Other_IKK_CHUK_ST	Q04206	RELA	O15111	CHUK	S240	A235S	235	Missense	distal	-5	no	182.427	197.687	EPSD	ICGC;COSMIC	187.474	Gain
Other_IKK_CHUK_ST	Q04206	RELA	O15111	CHUK	S240	R236Q	236	Missense	distal	-4	no	182.427	187.886	EPSD	ICGC;COSMIC	187.474	Gain
Other_IKK_CHUK_ST	Q04206	RELA	O15111	CHUK	S536	A538V	538	Missense	proximal	2	no	262.961	263.477	PhosphoSitePlus	ICGC;COSMIC	187.474	Up-regulation
Other_IKK_CHUK_ST	Q04206	RELA	O15111	CHUK	S547	Q548P	548	Missense	proximal	1	no	233.040	235.699	EPSD	ICGC;COSMIC	187.474	Up-regulation
Other_IKK_CHUK_ST	Q86VP1	TAX1BP1	O15111	CHUK	S212	K214Q	214	Missense	proximal	2	no	210.011	207.325	EPSD	ICGC	187.474	Down-regulation
Other_IKK_CHUK_ST	Q86VP1	TAX1BP1	O15111	CHUK	S212	G205V	205	Missense	distal	-7	no	210.011	206.871	EPSD	ICGC;COSMIC	187.474	Down-regulation
Other_IKK_CHUK_ST	Q86VP1	TAX1BP1	O15111	CHUK	S254	E251K	251	Missense	distal	-3	no	237.788	244.562	EPSD	ICGC;COSMIC;CCLE	187.474	Up-regulation
Other_IKK_CHUK_ST	Q86VP1	TAX1BP1	O15111	CHUK	S345	S344L	344	Missense	proximal	-1	no	228.914	229.844	EPSD	ICGC;COSMIC	187.474	Up-regulation
Other_IKK_CHUK_ST	Q86VP1	TAX1BP1	O15111	CHUK	S345	L340M	340	Missense	distal	-5	no	228.914	235.523	EPSD	ICGC	187.474	Up-regulation
Other_IKK_CHUK_ST	Q86VP1	TAX1BP1	O15111	CHUK	S499	D495A	495	Missense	distal	-4	no	220.742	220.796	EPSD	ICGC;COSMIC	187.474	Up-regulation
Other_IKK_CHUK_ST	Q86VP1	TAX1BP1	O15111	CHUK	S501	D495A	495	Missense	distal	-6	no	192.712	196.797	EPSD	ICGC;COSMIC	187.474	Up-regulation
Other_IKK_CHUK_ST	Q86VP1	TAX1BP1	O15111	CHUK	S593	A598S	598	Missense	distal	5	no	194.169	193.566	EPSD;PhosphoSitePlus	ICGC	187.474	Down-regulation
Other_IKK_CHUK_ST	Q15717	ELAVL1	O15111	CHUK	S41	S42I	42	Missense	proximal	1	no	178.639	190.473	EPSD	ICGC;COSMIC	187.474	Gain
Other_IKK_CHUK_ST	Q15717	ELAVL1	O15111	CHUK	S42	S42I	42	Missense	central	0	yes	193.084	0.000	EPSD	ICGC;COSMIC	187.474	Loss
Other_IKK_CHUK_ST	Q15717	ELAVL1	O15111	CHUK	S42	V46G	46	Missense	distal	4	no	193.084	185.968	EPSD	ICGC;COSMIC	187.474	Loss
Other_IKK_CHUK_ST	Q15717	ELAVL1	O15111	CHUK	S42	V46I	46	Missense	distal	4	no	193.084	194.488	EPSD	ICGC;COSMIC	187.474	Up-regulation
Other_IKK_CHUK_ST	Q15717	ELAVL1	O15111	CHUK	S242	N239K	239	Missense	distal	-3	no	195.762	204.049	EPSD	ICGC	187.474	Up-regulation
Other_IKK_CHUK_ST	Q15717	ELAVL1	O15111	CHUK	S318	H325N	325	Missense	distal	7	no	233.552	226.065	EPSD	ICGC	187.474	Down-regulation
Other_IKK_CHUK_ST	Q15717	ELAVL1	O15111	CHUK	S318	H325Q	325	Missense	distal	7	no	233.552	224.154	EPSD	ICGC	187.474	Down-regulation
Other_IKK_CHUK_ST	Q15717	ELAVL1	O15111	CHUK	S318	Q316K	316	Missense	proximal	-2	no	233.552	216.536	EPSD	ICGC	187.474	Down-regulation
Other_IKK_CHUK_ST	P24385	CCND1	O15111	CHUK	S197	K194N	194	Missense	distal	-3	no	194.072	185.784	EPSD	ICGC	187.474	Loss
Other_IKK_CHUK_ST	P24385	CCND1	O15111	CHUK	T286	D289N	289	Missense	distal	3	no	205.012	168.051	PhosphoSitePlus	ICGC;COSMIC	187.474	Loss
Other_IKK_CHUK_ST	P24385	CCND1	O15111	CHUK	T286	E280D	280	Missense	distal	-6	no	205.012	201.787	PhosphoSitePlus	ICGC	187.474	Down-regulation
Other_IKK_CHUK_ST	P24385	CCND1	O15111	CHUK	T286	P287A	287	Missense	proximal	1	no	205.012	197.555	PhosphoSitePlus	ICGC;COSMIC;GDSC;CCLE	187.474	Down-regulation
Other_IKK_CHUK_ST	P20749	BCL3	O15111	CHUK	S41	A46S	46	Missense	distal	5	no	220.483	219.880	EPSD	ICGC	187.474	Down-regulation
Other_IKK_CHUK_ST	P20749	BCL3	O15111	CHUK	S448	V445L	445	Missense	distal	-3	no	198.077	182.345	EPSD	ICGC	187.474	Loss
Other_IKK_CHUK_ST	O43524	FOXO3	O15111	CHUK	S12	P10T	10	Missense	proximal	-2	no	185.957	214.000	EPSD	ICGC;COSMIC	187.474	Gain
Other_IKK_CHUK_ST	O43524	FOXO3	O15111	CHUK	S55	D62N	62	Missense	distal	7	no	189.599	185.914	EPSD	ICGC	187.474	Loss
Other_IKK_CHUK_ST	O43524	FOXO3	O15111	CHUK	S75	G80S	80	Missense	distal	5	no	199.097	197.721	EPSD	ICGC;COSMIC	187.474	Down-regulation
Other_IKK_CHUK_ST	O43524	FOXO3	O15111	CHUK	S161	T167I	167	Missense	distal	6	no	192.266	198.804	EPSD	ICGC;COSMIC	187.474	Up-regulation
Other_IKK_CHUK_ST	O43524	FOXO3	O15111	CHUK	S161	T167A	167	Missense	distal	6	no	192.266	196.985	EPSD	ICGC;COSMIC	187.474	Up-regulation
Other_IKK_CHUK_ST	O43524	FOXO3	O15111	CHUK	S161	R168S	168	Missense	distal	7	no	192.266	180.568	EPSD	ICGC;COSMIC	187.474	Loss
Other_IKK_CHUK_ST	O43524	FOXO3	O15111	CHUK	S161	R168H	168	Missense	distal	7	no	192.266	188.902	EPSD	ICGC;COSMIC	187.474	Down-regulation
Other_IKK_CHUK_ST	O43524	FOXO3	O15111	CHUK	S202	G198C	198	Missense	distal	-4	no	209.165	192.203	EPSD	ICGC;COSMIC	187.474	Down-regulation
Other_IKK_CHUK_ST	O43524	FOXO3	O15111	CHUK	S202	D199N	199	Missense	distal	-3	no	209.165	207.516	EPSD	ICGC;COSMIC	187.474	Down-regulation
Other_IKK_CHUK_ST	O43524	FOXO3	O15111	CHUK	S209	R211W	211	Missense	proximal	2	no	185.204	189.359	EPSD	ICGC;COSMIC	187.474	Gain
Other_IKK_CHUK_ST	O43524	FOXO3	O15111	CHUK	S215	R211Q	211	Missense	distal	-4	no	183.173	188.633	EPSD	ICGC;COSMIC	187.474	Gain
Other_IKK_CHUK_ST	O43524	FOXO3	O15111	CHUK	S253	R249L	249	Missense	distal	-4	no	196.328	179.727	EPSD	ICGC;COSMIC	187.474	Loss
Other_IKK_CHUK_ST	O43524	FOXO3	O15111	CHUK	S330	S330N	330	Missense	central	0	yes	198.782	0.000	EPSD	ICGC;COSMIC	187.474	Loss
Other_IKK_CHUK_ST	O43524	FOXO3	O15111	CHUK	S644	G637V	637	Missense	distal	-7	no	217.602	214.462	PhosphoSitePlus	ICGC	187.474	Down-regulation
Other_IKK_CHUK_ST	O43524	FOXO3	O15111	CHUK	S666	S669I	669	Missense	distal	3	no	208.886	170.168	EPSD	ICGC;COSMIC	187.474	Loss
Other_IKK_CHUK_ST	O43524	FOXO3	O15111	CHUK	S667	S669I	669	Missense	proximal	2	no	191.044	192.312	EPSD	ICGC;COSMIC	187.474	Up-regulation
Other_IKK_CHUK_ST	O43524	FOXO3	O15111	CHUK	S669	S669I	669	Missense	central	0	yes	222.725	0.000	EPSD	ICGC;COSMIC	187.474	Loss
Other_IKK_CHUK_ST	Q04864	REL	O15111	CHUK	S386	G379W	379	Missense	distal	-7	no	211.624	207.777	EPSD	ICGC;COSMIC	187.474	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	O75469	NR1I2	P24941	CDK2	S114	D115V	115	Missense	proximal	1	no	9.116	0.448	PhosphoSitePlus;EPSD	ICGC	8.148	Loss
CMGC_CDK_CDK2_CDK2_ST	O75469	NR1I2	P24941	CDK2	S114	R121M	121	Missense	distal	7	no	9.116	9.172	PhosphoSitePlus;EPSD	ICGC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	O75469	NR1I2	P24941	CDK2	S114	A117S	117	Missense	distal	3	no	9.116	9.662	PhosphoSitePlus;EPSD	ICGC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	O75469	NR1I2	P24941	CDK2	S114	M113I	113	Missense	proximal	-1	no	9.116	8.050	PhosphoSitePlus;EPSD	ICGC;COSMIC	8.148	Loss
CMGC_CDK_CDK2_CDK2_ST	O75469	NR1I2	P24941	CDK2	S114	E120D	120	Missense	distal	6	no	9.116	9.104	PhosphoSitePlus;EPSD	ICGC;COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	O75469	NR1I2	P24941	CDK2	S114	I112T	112	Missense	proximal	-2	no	9.116	9.237	PhosphoSitePlus;EPSD	ICGC;COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	O75469	NR1I2	P24941	CDK2	S114	D115E	115	Missense	proximal	1	no	9.116	8.194	PhosphoSitePlus;EPSD	ICGC;COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	O75469	NR1I2	P24941	CDK2	S114	E116K	116	Missense	proximal	2	no	9.116	8.879	PhosphoSitePlus;EPSD	ICGC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	O75469	NR1I2	P24941	CDK2	T133	R132W	132	Missense	proximal	-1	no	8.159	8.713	EPSD;PhosphoSitePlus	ICGC;COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	O75469	NR1I2	P24941	CDK2	T133	R132L	132	Missense	proximal	-1	no	8.159	7.409	EPSD;PhosphoSitePlus	ICGC	8.148	Loss
CMGC_CDK_CDK2_CDK2_ST	O75469	NR1I2	P24941	CDK2	T133	L138Q	138	Missense	distal	5	no	8.159	8.079	EPSD;PhosphoSitePlus	ICGC;COSMIC	8.148	Loss
CMGC_CDK_CDK2_CDK2_ST	O75469	NR1I2	P24941	CDK2	T133	K128T	128	Missense	distal	-5	no	8.159	8.155	EPSD;PhosphoSitePlus	ICGC;COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	O75469	NR1I2	P24941	CDK2	T135	R132W	132	Missense	distal	-3	no	9.815	9.896	EPSD;PhosphoSitePlus	ICGC;COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	O75469	NR1I2	P24941	CDK2	T135	R132L	132	Missense	distal	-3	no	9.815	9.556	EPSD;PhosphoSitePlus	ICGC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	O75469	NR1I2	P24941	CDK2	T135	L138Q	138	Missense	distal	3	no	9.815	10.174	EPSD;PhosphoSitePlus	ICGC;COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	O75469	NR1I2	P24941	CDK2	T135	Q141K	141	Missense	distal	6	no	9.815	9.818	EPSD;PhosphoSitePlus	ICGC;COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	O75469	NR1I2	P24941	CDK2	T135	Q141H	141	Missense	distal	6	no	9.815	9.805	EPSD;PhosphoSitePlus	ICGC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	O75469	NR1I2	P24941	CDK2	T135	K128T	128	Missense	distal	-7	no	9.815	9.860	EPSD;PhosphoSitePlus	ICGC;COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	O75469	NR1I2	P24941	CDK2	S167	R173Q	173	Missense	distal	6	no	12.284	12.305	EPSD;PhosphoSitePlus	ICGC;COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	O75469	NR1I2	P24941	CDK2	S167	L174M	174	Missense	distal	7	no	12.284	12.798	EPSD;PhosphoSitePlus	ICGC;COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	O75469	NR1I2	P24941	CDK2	S167	F162Y	162	Missense	distal	-5	no	12.284	12.236	EPSD;PhosphoSitePlus	ICGC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	O75469	NR1I2	P24941	CDK2	S200	V202A	202	Missense	proximal	2	no	11.536	11.438	EPSD;PhosphoSitePlus	ICGC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	O75469	NR1I2	P24941	CDK2	S200	S200N	200	Missense	central	0	yes	11.536	0.000	EPSD;PhosphoSitePlus	ICGC;COSMIC	8.148	Loss
CMGC_CDK_CDK2_CDK2_ST	O95295	SNAPIN	P24941	CDK2	T14	A12S	12	Missense	proximal	-2	no	13.135	12.468	EPSD	ICGC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	O95295	SNAPIN	P24941	CDK2	T14	S10L	10	Missense	distal	-4	no	13.135	12.723	EPSD	ICGC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	O95295	SNAPIN	P24941	CDK2	S126	S126L	126	Missense	central	0	yes	8.303	0.000	EPSD	ICGC	8.148	Loss
CMGC_CDK_CDK2_CDK2_ST	O95295	SNAPIN	P24941	CDK2	S126	P131H	131	Missense	distal	5	no	8.303	8.381	EPSD	ICGC;COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	O95295	SNAPIN	P24941	CDK2	S133	S126L	126	Missense	distal	-7	no	18.746	18.932	PhosphoSitePlus	ICGC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	O95295	SNAPIN	P24941	CDK2	S133	P131H	131	Missense	proximal	-2	no	18.746	17.736	PhosphoSitePlus	ICGC;COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	O95295	SNAPIN	P24941	CDK2	S133	P134T	134	Missense	proximal	1	no	18.746	8.789	PhosphoSitePlus	ICGC;COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	Q99638	RAD9A	P24941	CDK2	S277	Q273E	273	Missense	distal	-4	no	17.034	17.482	EPSD	ICGC;COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	Q99638	RAD9A	P24941	CDK2	T292	D297Y	297	Missense	distal	5	no	12.997	12.897	EPSD	ICGC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	Q99638	RAD9A	P24941	CDK2	S328	P331S	331	Missense	distal	3	no	14.304	14.338	PhosphoSitePlus	ICGC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	Q99638	RAD9A	P24941	CDK2	S328	P329L	329	Missense	proximal	1	no	14.304	4.483	PhosphoSitePlus	ICGC	8.148	Loss
CMGC_CDK_CDK2_CDK2_ST	Q99638	RAD9A	P24941	CDK2	S336	E342K	342	Missense	distal	6	no	14.003	14.014	EPSD	ICGC;COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	Q99638	RAD9A	P24941	CDK2	S336	P331S	331	Missense	distal	-5	no	14.003	13.958	EPSD	ICGC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	Q99638	RAD9A	P24941	CDK2	S336	P329L	329	Missense	distal	-7	no	14.003	14.008	EPSD	ICGC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	Q99638	RAD9A	P24941	CDK2	T355	P349S	349	Missense	distal	-6	no	14.044	14.043	EPSD	ICGC;COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	Q99638	RAD9A	P24941	CDK2	S375	R374H	374	Missense	proximal	-1	no	14.914	14.463	EPSD	ICGC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	Q99638	RAD9A	P24941	CDK2	S375	P372H	372	Missense	distal	-3	no	14.914	15.060	EPSD	ICGC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	Q99638	RAD9A	P24941	CDK2	S375	Q377K	377	Missense	proximal	2	no	14.914	14.714	EPSD	ICGC;COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	Q99638	RAD9A	P24941	CDK2	S380	R374H	374	Missense	distal	-6	no	13.307	13.308	EPSD	ICGC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	Q99638	RAD9A	P24941	CDK2	S380	Q377K	377	Missense	distal	-3	no	13.307	13.208	EPSD	ICGC;COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	Q8IZL8	PELP1	P24941	CDK2	S29	A26E	26	Missense	distal	-3	no	7.933	8.166	EPSD	ICGC	8.148	Gain
CMGC_CDK_CDK2_CDK2_ST	Q8IZL8	PELP1	P24941	CDK2	S29	S28F	28	Missense	proximal	-1	no	7.933	9.190	EPSD	ICGC;COSMIC	8.148	Gain
CMGC_CDK_CDK2_CDK2_ST	Q8IZL8	PELP1	P24941	CDK2	T647	P648T	648	Missense	proximal	1	no	11.719	1.762	EPSD	ICGC	8.148	Loss
CMGC_CDK_CDK2_CDK2_ST	Q8IZL8	PELP1	P24941	CDK2	S991	P993L	993	Missense	proximal	2	no	16.884	16.777	EPSD;PhosphoSitePlus	ICGC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	Q07820	MCL1	P24941	CDK2	T92	V86L	86	Missense	distal	-6	no	17.383	17.382	PhosphoSitePlus;EPSD	ICGC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	Q07820	MCL1	P24941	CDK2	T92	E85D	85	Missense	distal	-7	no	17.383	17.534	PhosphoSitePlus;EPSD	ICGC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	Q07820	MCL1	P24941	CDK2	T92	A94T	94	Missense	proximal	2	no	17.383	17.181	PhosphoSitePlus;EPSD	ICGC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	Q07820	MCL1	P24941	CDK2	T92	R95S	95	Missense	distal	3	no	17.383	15.699	PhosphoSitePlus;EPSD	ICGC;COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	Q07820	MCL1	P24941	CDK2	T92	T92P	92	Missense	central	0	yes	17.383	0.000	PhosphoSitePlus;EPSD	ICGC;COSMIC	8.148	Loss
CMGC_CDK_CDK2_CDK2_ST	Q07820	MCL1	P24941	CDK2	S121	I119V	119	Missense	proximal	-2	no	15.691	15.195	EPSD;PhosphoSitePlus	ICGC;COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	Q07820	MCL1	P24941	CDK2	S121	E125D	125	Missense	distal	4	no	15.691	15.609	EPSD;PhosphoSitePlus	ICGC;COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	Q07820	MCL1	P24941	CDK2	T163	T156A	156	Missense	distal	-7	no	13.606	13.774	EPSD;PhosphoSitePlus	ICGC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	Q07820	MCL1	P24941	CDK2	T163	P161S	161	Missense	proximal	-2	no	13.606	12.955	EPSD;PhosphoSitePlus	ICGC;COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	Q07820	MCL1	P24941	CDK2	T163	P166Q	166	Missense	distal	3	no	13.606	13.582	EPSD;PhosphoSitePlus	ICGC;COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	Q07820	MCL1	P24941	CDK2	S202	D195Y	195	Missense	distal	-7	no	8.475	8.359	EPSD	ICGC;COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	Q07820	MCL1	P24941	CDK2	S202	P198A	198	Missense	distal	-4	no	8.475	8.416	EPSD	ICGC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	Q07820	MCL1	P24941	CDK2	S202	M199K	199	Missense	distal	-3	no	8.475	8.066	EPSD	ICGC	8.148	Loss
CMGC_CDK_CDK2_CDK2_ST	Q07820	MCL1	P24941	CDK2	S202	S206R	206	Missense	distal	4	no	8.475	8.341	EPSD	ICGC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	Q07820	MCL1	P24941	CDK2	S202	K197E	197	Missense	distal	-5	no	8.475	8.509	EPSD	ICGC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	Q08999	RBL2	P24941	CDK2	S8	P10L	10	Missense	proximal	2	no	11.659	11.553	EPSD	ICGC;COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	Q08999	RBL2	P24941	CDK2	S8	P14L	14	Missense	distal	6	no	11.659	11.661	EPSD	ICGC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	Q08999	RBL2	P24941	CDK2	S40	E39K	39	Missense	proximal	-1	no	15.777	14.892	EPSD	ICGC;COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	Q08999	RBL2	P24941	CDK2	S40	A38S	38	Missense	proximal	-2	no	15.777	15.110	EPSD	ICGC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	Q08999	RBL2	P24941	CDK2	S40	Q46K	46	Missense	distal	6	no	15.777	15.780	EPSD	ICGC;COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	Q08999	RBL2	P24941	CDK2	S40	P36L	36	Missense	distal	-4	no	15.777	15.719	EPSD	ICGC;COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	Q08999	RBL2	P24941	CDK2	T42	E39K	39	Missense	distal	-3	no	16.099	15.884	EPSD	ICGC;COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	Q08999	RBL2	P24941	CDK2	T42	A38S	38	Missense	distal	-4	no	16.099	16.512	EPSD	ICGC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	Q08999	RBL2	P24941	CDK2	T42	Q46K	46	Missense	distal	4	no	16.099	16.440	EPSD	ICGC;COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	Q08999	RBL2	P24941	CDK2	S662	Y667C	667	Missense	distal	5	no	15.758	15.919	EPSD;PhosphoSitePlus	ICGC;COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	Q08999	RBL2	P24941	CDK2	S662	R669S	669	Missense	distal	7	no	15.758	15.117	EPSD;PhosphoSitePlus	ICGC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	Q08999	RBL2	P24941	CDK2	S672	Y667C	667	Missense	distal	-5	no	15.811	15.867	EPSD	ICGC;COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	Q08999	RBL2	P24941	CDK2	S672	S672F	672	Missense	central	0	yes	15.811	0.000	EPSD	ICGC	8.148	Loss
CMGC_CDK_CDK2_CDK2_ST	Q08999	RBL2	P24941	CDK2	S672	R669S	669	Missense	distal	-3	no	15.811	15.717	EPSD	ICGC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	Q08999	RBL2	P24941	CDK2	S672	P674T	674	Missense	proximal	2	no	15.811	15.633	EPSD	ICGC;COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	Q08999	RBL2	P24941	CDK2	S688	D691V	691	Missense	distal	3	no	12.799	15.221	EPSD;PhosphoSitePlus	ICGC;COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	Q08999	RBL2	P24941	CDK2	S688	G693E	693	Missense	distal	5	no	12.799	12.751	EPSD;PhosphoSitePlus	ICGC;COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	Q08999	RBL2	P24941	CDK2	T694	D691V	691	Missense	distal	-3	no	14.813	14.891	EPSD;PhosphoSitePlus	ICGC;COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	Q08999	RBL2	P24941	CDK2	T694	P699T	699	Missense	distal	5	no	14.813	14.788	EPSD;PhosphoSitePlus	ICGC;COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	Q08999	RBL2	P24941	CDK2	T694	R697C	697	Missense	distal	3	no	14.813	8.449	EPSD;PhosphoSitePlus	ICGC;COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	Q08999	RBL2	P24941	CDK2	T694	G693E	693	Missense	proximal	-1	no	14.813	14.550	EPSD;PhosphoSitePlus	ICGC;COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	Q08999	RBL2	P24941	CDK2	S952	S952C	952	Missense	central	0	yes	14.436	0.000	EPSD;PhosphoSitePlus	ICGC;COSMIC	8.148	Loss
CMGC_CDK_CDK2_CDK2_ST	Q08999	RBL2	P24941	CDK2	S952	D945E	945	Missense	distal	-7	no	14.436	14.285	EPSD;PhosphoSitePlus	ICGC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	Q08999	RBL2	P24941	CDK2	S995	M997T	997	Missense	proximal	2	no	9.084	8.695	EPSD	ICGC;COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	Q08999	RBL2	P24941	CDK2	S995	M997V	997	Missense	proximal	2	no	9.084	8.995	EPSD	ICGC;COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	Q08999	RBL2	P24941	CDK2	S1035	A1031G	1031	Missense	distal	-4	no	12.670	12.411	EPSD	ICGC;COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	P10636	MAPT	P24941	CDK2	T111	D116E	116	Missense	distal	5	no	13.764	13.669	EPSD	ICGC;COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	P10636	MAPT	P24941	CDK2	T173	A166T	166	Missense	distal	-7	no	9.577	9.410	EPSD	ICGC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	P10636	MAPT	P24941	CDK2	S228	P233H	233	Missense	distal	5	no	9.983	10.061	EPSD	ICGC;COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	P10636	MAPT	P24941	CDK2	S228	S232F	232	Missense	distal	4	no	9.983	9.787	EPSD	ICGC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	P10636	MAPT	P24941	CDK2	S228	D225N	225	Missense	distal	-3	no	9.983	9.939	EPSD	ICGC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	P10636	MAPT	P24941	CDK2	S228	V224I	224	Missense	distal	-4	no	9.983	9.880	EPSD	ICGC;COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	P10636	MAPT	P24941	CDK2	S232	P233H	233	Missense	proximal	1	no	15.341	8.583	EPSD	ICGC;COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	P10636	MAPT	P24941	CDK2	S232	S232F	232	Missense	central	0	yes	15.341	0.000	EPSD	ICGC	8.148	Loss
CMGC_CDK_CDK2_CDK2_ST	P10636	MAPT	P24941	CDK2	S232	D225N	225	Missense	distal	-7	no	15.341	15.019	EPSD	ICGC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	P10636	MAPT	P24941	CDK2	S232	P239Q	239	Missense	distal	7	no	15.341	15.187	EPSD	ICGC;COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	P10636	MAPT	P24941	CDK2	S238	P233H	233	Missense	distal	-5	no	14.454	14.501	EPSD	ICGC;COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	P10636	MAPT	P24941	CDK2	S238	S232F	232	Missense	distal	-6	no	14.454	14.459	EPSD	ICGC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	P10636	MAPT	P24941	CDK2	S238	P239Q	239	Missense	proximal	1	no	14.454	6.542	EPSD	ICGC;COSMIC	8.148	Loss
CMGC_CDK_CDK2_CDK2_ST	P10636	MAPT	P24941	CDK2	S428	S427F	427	Missense	proximal	-1	no	13.464	14.721	EPSD	ICGC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	P10636	MAPT	P24941	CDK2	S438	Y441H	441	Missense	distal	3	no	13.556	15.324	EPSD	ICGC;COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	P10636	MAPT	P24941	CDK2	S516	G521R	521	Missense	distal	5	no	12.476	12.456	EPSD	ICGC;COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	P10636	MAPT	P24941	CDK2	S519	G521R	521	Missense	proximal	2	no	16.829	16.870	EPSD	ICGC;COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	P10636	MAPT	P24941	CDK2	T522	G521R	521	Missense	proximal	-1	no	12.687	12.209	EPSD	ICGC;COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	Q99728	BARD1	P24941	CDK2	S148	V154A	154	Missense	distal	6	no	13.307	13.305	EPSD;PhosphoSitePlus	ICGC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	Q99728	BARD1	P24941	CDK2	S184	S184Y	184	Missense	central	0	yes	12.220	0.000	EPSD	ICGC	8.148	Loss
CMGC_CDK_CDK2_CDK2_ST	Q99728	BARD1	P24941	CDK2	S186	S184Y	184	Missense	proximal	-2	no	9.780	9.867	EPSD	ICGC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	Q99728	BARD1	P24941	CDK2	S251	I258T	258	Missense	distal	7	no	15.213	14.852	PhosphoSitePlus;EPSD	ICGC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	Q99728	BARD1	P24941	CDK2	S251	S247Y	247	Missense	distal	-4	no	15.213	15.324	PhosphoSitePlus;EPSD	ICGC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	Q99728	BARD1	P24941	CDK2	S288	P281Q	281	Missense	distal	-7	no	14.800	14.757	EPSD;PhosphoSitePlus	ICGC;COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	Q99728	BARD1	P24941	CDK2	S391	S397F	397	Missense	distal	6	no	13.256	13.236	EPSD	ICGC;COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	Q99728	BARD1	P24941	CDK2	T394	S397F	397	Missense	distal	3	no	13.132	13.057	EPSD	ICGC;COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	Q99728	BARD1	P24941	CDK2	S410	V407M	407	Missense	distal	-3	no	9.833	10.058	EPSD	ICGC;COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	Q99728	BARD1	P24941	CDK2	S410	P411H	411	Missense	proximal	1	no	9.833	3.074	EPSD	ICGC;COSMIC	8.148	Loss
CMGC_CDK_CDK2_CDK2_ST	Q99728	BARD1	P24941	CDK2	S496	Q493E	493	Missense	distal	-3	no	13.404	13.521	EPSD	ICGC;COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	Q99728	BARD1	P24941	CDK2	S496	L498I	498	Missense	proximal	2	no	13.404	13.488	EPSD	ICGC;COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	Q99728	BARD1	P24941	CDK2	S555	M560I	560	Missense	distal	5	no	8.657	8.442	EPSD	ICGC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	Q99728	BARD1	P24941	CDK2	S555	S555R	555	Missense	central	0	yes	8.657	0.000	EPSD	ICGC	8.148	Loss
CMGC_CDK_CDK2_CDK2_ST	O43303	CCP110	P24941	CDK2	S45	G40V	40	Missense	distal	-5	no	13.942	13.894	PhosphoSitePlus;EPSD	ICGC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	O43303	CCP110	P24941	CDK2	S170	P171L	171	Missense	proximal	1	no	11.005	1.184	EPSD;PhosphoSitePlus	ICGC;COSMIC	8.148	Loss
CMGC_CDK_CDK2_CDK2_ST	O43303	CCP110	P24941	CDK2	S170	D175Y	175	Missense	distal	5	no	11.005	10.905	EPSD;PhosphoSitePlus	ICGC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	O43303	CCP110	P24941	CDK2	S366	P365H	365	Missense	proximal	-1	no	13.818	13.938	EPSD;PhosphoSitePlus	ICGC;COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	O43303	CCP110	P24941	CDK2	S366	G359C	359	Missense	distal	-7	no	13.818	13.765	EPSD;PhosphoSitePlus	ICGC;COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	O43303	CCP110	P24941	CDK2	S372	M375I	375	Missense	distal	3	no	15.180	14.752	EPSD;PhosphoSitePlus	ICGC;COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	O43303	CCP110	P24941	CDK2	S372	M375V	375	Missense	distal	3	no	15.180	16.028	EPSD;PhosphoSitePlus	ICGC;COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	O43303	CCP110	P24941	CDK2	S372	P365H	365	Missense	distal	-7	no	15.180	15.303	EPSD;PhosphoSitePlus	ICGC;COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	O43303	CCP110	P24941	CDK2	T566	T560M	560	Missense	distal	-6	no	12.381	12.389	EPSD;PhosphoSitePlus	ICGC;COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	O43303	CCP110	P24941	CDK2	S788	F791V	791	Missense	distal	3	no	8.763	9.412	EPSD	ICGC;COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	Q15648	MED1	P24941	CDK2	T212	P213A	213	Missense	proximal	1	no	12.211	-2.192	EPSD	ICGC;COSMIC	8.148	Loss
CMGC_CDK_CDK2_CDK2_ST	Q15648	MED1	P24941	CDK2	T212	R214K	214	Missense	proximal	2	no	12.211	11.911	EPSD	ICGC;COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	Q15648	MED1	P24941	CDK2	S434	L437R	437	Missense	distal	3	no	11.706	13.808	EPSD	ICGC;COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	Q15648	MED1	P24941	CDK2	T522	Q519H	519	Missense	distal	-3	no	14.849	14.937	EPSD	ICGC;COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	Q15648	MED1	P24941	CDK2	S545	K538N	538	Missense	distal	-7	no	10.255	10.221	EPSD	ICGC;COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	Q15648	MED1	P24941	CDK2	S558	M557V	557	Missense	proximal	-1	no	8.350	7.257	EPSD	ICGC	8.148	Loss
CMGC_CDK_CDK2_CDK2_ST	Q15648	MED1	P24941	CDK2	T562	M557V	557	Missense	distal	-5	no	13.317	13.241	EPSD	ICGC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	Q15648	MED1	P24941	CDK2	T562	P568L	568	Missense	distal	6	no	13.317	13.318	EPSD	ICGC;COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	Q15648	MED1	P24941	CDK2	S675	P676S	676	Missense	proximal	1	no	14.437	3.172	EPSD	ICGC;COSMIC	8.148	Loss
CMGC_CDK_CDK2_CDK2_ST	Q15648	MED1	P24941	CDK2	S675	P676L	676	Missense	proximal	1	no	14.437	4.617	EPSD	ICGC;COSMIC	8.148	Loss
CMGC_CDK_CDK2_CDK2_ST	Q15648	MED1	P24941	CDK2	T747	P749L	749	Missense	proximal	2	no	10.825	10.718	EPSD	ICGC;COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	Q15648	MED1	P24941	CDK2	T747	P748R	748	Missense	proximal	1	no	10.825	1.026	EPSD	ICGC	8.148	Loss
CMGC_CDK_CDK2_CDK2_ST	Q15648	MED1	P24941	CDK2	T805	P801Q	801	Missense	distal	-4	no	17.602	17.384	EPSD	ICGC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	Q15648	MED1	P24941	CDK2	T805	I803V	803	Missense	proximal	-2	no	17.602	17.107	EPSD	ICGC;COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	Q15648	MED1	P24941	CDK2	T1051	T1051I	1051	Missense	central	0	yes	11.862	0.000	EPSD	ICGC;COSMIC	8.148	Loss
CMGC_CDK_CDK2_CDK2_ST	Q15648	MED1	P24941	CDK2	T1057	T1051I	1051	Missense	distal	-6	no	10.178	10.180	EPSD	ICGC;COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	Q15648	MED1	P24941	CDK2	T1057	T1064A	1064	Missense	distal	7	no	10.178	10.866	EPSD	ICGC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	Q15648	MED1	P24941	CDK2	S1156	L1163P	1163	Missense	distal	7	no	12.453	12.423	EPSD	ICGC;COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	Q15648	MED1	P24941	CDK2	S1156	H1161N	1161	Missense	distal	5	no	12.453	12.478	EPSD	ICGC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	Q15648	MED1	P24941	CDK2	S1192	S1192F	1192	Missense	central	0	yes	13.648	0.000	EPSD	ICGC;GDSC;CCLE	8.148	Loss
CMGC_CDK_CDK2_CDK2_ST	Q15648	MED1	P24941	CDK2	S1207	P1208Q	1208	Missense	proximal	1	no	17.974	10.063	PhosphoSitePlus;EPSD	ICGC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	Q15648	MED1	P24941	CDK2	T1215	T1215N	1215	Missense	central	0	yes	16.403	0.000	EPSD;PhosphoSitePlus	ICGC;COSMIC	8.148	Loss
CMGC_CDK_CDK2_CDK2_ST	Q15648	MED1	P24941	CDK2	T1215	P1208Q	1208	Missense	distal	-7	no	16.403	16.360	EPSD;PhosphoSitePlus	ICGC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	Q15648	MED1	P24941	CDK2	S1223	P1224L	1224	Missense	proximal	1	no	14.926	5.105	EPSD	ICGC;COSMIC	8.148	Loss
CMGC_CDK_CDK2_CDK2_ST	Q15648	MED1	P24941	CDK2	S1229	H1233R	1233	Missense	distal	4	no	8.322	8.440	EPSD	ICGC;COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	Q15648	MED1	P24941	CDK2	S1229	P1224L	1224	Missense	distal	-5	no	8.322	8.334	EPSD	ICGC;COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	Q15648	MED1	P24941	CDK2	S1229	G1231C	1231	Missense	proximal	2	no	8.322	8.350	EPSD	ICGC;COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	Q15648	MED1	P24941	CDK2	S1294	P1301Q	1301	Missense	distal	7	no	16.915	16.760	EPSD	ICGC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	Q15648	MED1	P24941	CDK2	S1294	S1294C	1294	Missense	central	0	yes	16.915	0.000	EPSD	ICGC;COSMIC	8.148	Loss
CMGC_CDK_CDK2_CDK2_ST	Q15648	MED1	P24941	CDK2	S1379	S1386R	1386	Missense	distal	7	no	9.203	9.845	EPSD	ICGC;COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	Q15648	MED1	P24941	CDK2	S1379	T1378N	1378	Missense	proximal	-1	no	9.203	9.393	EPSD	ICGC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	Q15648	MED1	P24941	CDK2	S1433	S1433P	1433	Missense	central	0	yes	12.510	0.000	EPSD	ICGC	8.148	Loss
CMGC_CDK_CDK2_CDK2_ST	Q15648	MED1	P24941	CDK2	S1433	S1437R	1437	Missense	distal	4	no	12.510	12.376	EPSD	ICGC;COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	Q15648	MED1	P24941	CDK2	S1439	S1433P	1433	Missense	distal	-6	no	9.100	9.101	EPSD	ICGC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	Q15648	MED1	P24941	CDK2	S1439	S1437R	1437	Missense	proximal	-2	no	9.100	8.515	EPSD	ICGC;COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	Q15648	MED1	P24941	CDK2	T1440	S1433P	1433	Missense	distal	-7	no	13.335	13.515	EPSD	ICGC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	Q15648	MED1	P24941	CDK2	T1440	S1437R	1437	Missense	distal	-3	no	13.335	13.428	EPSD	ICGC;COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	Q15648	MED1	P24941	CDK2	T1457	E1464K	1464	Missense	distal	7	no	12.822	12.492	EPSD	ICGC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	Q15648	MED1	P24941	CDK2	S1536	S1539C	1539	Missense	distal	3	no	14.103	9.423	EPSD	ICGC;COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	Q15648	MED1	P24941	CDK2	S1561	D1555E	1555	Missense	distal	-6	no	15.660	15.664	EPSD	ICGC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	Q15648	MED1	P24941	CDK2	S1561	S1561R	1561	Missense	central	0	yes	15.660	0.000	EPSD	ICGC;COSMIC	8.148	Loss
CMGC_CDK_CDK2_CDK2_ST	P62324	BTG1	P24941	CDK2	S159	T158R	158	Missense	proximal	-1	no	16.830	17.664	PhosphoSitePlus	ICGC;COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	P19338	NCL	P24941	CDK2	S67	T69K	69	Missense	proximal	2	no	16.712	16.748	EPSD	ICGC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	P19338	NCL	P24941	CDK2	T76	P77T	77	Missense	proximal	1	no	14.850	4.892	EPSD;PhosphoSitePlus	ICGC	8.148	Loss
CMGC_CDK_CDK2_CDK2_ST	P19338	NCL	P24941	CDK2	T76	A81E	81	Missense	distal	5	no	14.850	14.919	EPSD;PhosphoSitePlus	ICGC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	P19338	NCL	P24941	CDK2	T76	T69K	69	Missense	distal	-7	no	14.850	14.805	EPSD;PhosphoSitePlus	ICGC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	P19338	NCL	P24941	CDK2	T84	P77T	77	Missense	distal	-7	no	16.617	16.614	EPSD	ICGC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	P19338	NCL	P24941	CDK2	T84	A81E	81	Missense	distal	-3	no	16.617	16.850	EPSD	ICGC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	P19338	NCL	P24941	CDK2	T84	P85Q	85	Missense	proximal	1	no	16.617	8.705	EPSD	ICGC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	P19338	NCL	P24941	CDK2	T92	P85Q	85	Missense	distal	-7	no	15.307	15.264	EPSD	ICGC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	P19338	NCL	P24941	CDK2	T99	A103E	103	Missense	distal	4	no	15.448	15.425	EPSD	ICGC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	P19338	NCL	P24941	CDK2	T99	T106K	106	Missense	distal	7	no	15.448	15.465	EPSD	ICGC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	P19338	NCL	P24941	CDK2	T99	A101D	101	Missense	proximal	2	no	15.448	15.420	EPSD	ICGC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	P19338	NCL	P24941	CDK2	T106	A112V	112	Missense	distal	6	no	16.791	16.793	EPSD	ICGC;COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	P19338	NCL	P24941	CDK2	T106	A103E	103	Missense	distal	-3	no	16.791	17.024	EPSD	ICGC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	P19338	NCL	P24941	CDK2	T106	T106K	106	Missense	central	0	yes	16.791	0.000	EPSD	ICGC	8.148	Loss
CMGC_CDK_CDK2_CDK2_ST	P19338	NCL	P24941	CDK2	T106	A101D	101	Missense	distal	-5	no	16.791	16.823	EPSD	ICGC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	P19338	NCL	P24941	CDK2	T113	A112V	112	Missense	proximal	-1	no	14.880	15.107	EPSD	ICGC;COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	P19338	NCL	P24941	CDK2	T113	T106K	106	Missense	distal	-7	no	14.880	14.835	EPSD	ICGC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	P19338	NCL	P24941	CDK2	S145	D150E	150	Missense	distal	5	no	9.344	9.250	EPSD	ICGC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	P19338	NCL	P24941	CDK2	S184	P182L	182	Missense	proximal	-2	no	9.836	9.612	EPSD	ICGC;COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	P19338	NCL	P24941	CDK2	T214	P215L	215	Missense	proximal	1	no	15.166	5.346	EPSD	ICGC;COSMIC	8.148	Loss
CMGC_CDK_CDK2_CDK2_ST	P13639	EEF2	P24941	CDK2	S279	S279R	279	Missense	central	0	yes	13.431	0.000	EPSD	ICGC;COSMIC	8.148	Loss
CMGC_CDK_CDK2_CDK2_ST	P13639	EEF2	P24941	CDK2	S279	G282W	282	Missense	distal	3	no	13.431	12.611	EPSD	ICGC;COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	P13639	EEF2	P24941	CDK2	S325	D320Y	320	Missense	distal	-5	no	9.540	9.507	EPSD	ICGC;COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	P13639	EEF2	P24941	CDK2	T435	I429S	429	Missense	distal	-6	no	17.218	17.215	PhosphoSitePlus;EPSD	ICGC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	P13639	EEF2	P24941	CDK2	T435	M430I	430	Missense	distal	-5	no	17.218	17.150	PhosphoSitePlus;EPSD	ICGC;COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	P13639	EEF2	P24941	CDK2	T435	G437V	437	Missense	proximal	2	no	17.218	17.223	PhosphoSitePlus;EPSD	ICGC;COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	P13639	EEF2	P24941	CDK2	S502	R495L	495	Missense	distal	-7	no	16.016	15.678	EPSD	ICGC;COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	P13639	EEF2	P24941	CDK2	S595	R601Q	601	Missense	distal	6	no	16.187	16.209	EPSD;PhosphoSitePlus	ICGC;COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	P13639	EEF2	P24941	CDK2	S595	H599Q	599	Missense	distal	4	no	16.187	16.486	EPSD;PhosphoSitePlus	ICGC;COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	P13639	EEF2	P24941	CDK2	T779	A786V	786	Missense	distal	7	no	16.791	16.665	EPSD	ICGC;COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	P13639	EEF2	P24941	CDK2	T779	E772K	772	Missense	distal	-7	no	16.791	16.654	EPSD	ICGC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	Q9NYV6	RRN3	P24941	CDK2	T200	S199L	199	Missense	proximal	-1	no	13.090	13.382	EPSD	ICGC;COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	Q9NYV6	RRN3	P24941	CDK2	T200	P201S	201	Missense	proximal	1	no	13.090	1.825	EPSD	ICGC;COSMIC	8.148	Loss
CMGC_CDK_CDK2_CDK2_ST	Q9H211	CDT1	P24941	CDK2	S79	P86S	86	Missense	distal	7	no	12.445	12.293	EPSD	ICGC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	Q9H211	CDT1	P24941	CDK2	S79	S79I	79	Missense	central	0	yes	12.445	0.000	EPSD	ICGC;COSMIC	8.148	Loss
CMGC_CDK_CDK2_CDK2_ST	Q9H211	CDT1	P24941	CDK2	T82	P86S	86	Missense	distal	4	no	13.985	13.999	EPSD	ICGC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	Q9H211	CDT1	P24941	CDK2	T82	S79I	79	Missense	distal	-3	no	13.985	13.910	EPSD	ICGC;COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	Q9H211	CDT1	P24941	CDK2	S93	P94T	94	Missense	proximal	1	no	13.057	3.100	EPSD	ICGC	8.148	Loss
CMGC_CDK_CDK2_CDK2_ST	Q9H211	CDT1	P24941	CDK2	S93	P86S	86	Missense	distal	-7	no	13.057	12.877	EPSD	ICGC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	Q9H211	CDT1	P24941	CDK2	S93	Q96K	96	Missense	distal	3	no	13.057	15.790	EPSD	ICGC;COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	Q9H211	CDT1	P24941	CDK2	T102	Q96K	96	Missense	distal	-6	no	11.500	11.497	EPSD	ICGC;COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	Q9H211	CDT1	P24941	CDK2	T152	A147S	147	Missense	distal	-5	no	11.611	11.541	EPSD	ICGC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	Q9H211	CDT1	P24941	CDK2	T213	P214L	214	Missense	proximal	1	no	13.571	3.750	EPSD	ICGC	8.148	Loss
CMGC_CDK_CDK2_CDK2_ST	Q9H211	CDT1	P24941	CDK2	S318	K311N	311	Missense	distal	-7	no	14.009	13.974	EPSD	ICGC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	Q9H211	CDT1	P24941	CDK2	T329	R330H	330	Missense	proximal	1	no	5.641	8.681	EPSD	ICGC;COSMIC;GDSC	8.148	Gain
CMGC_CDK_CDK2_CDK2_ST	Q9H211	CDT1	P24941	CDK2	S372	R368H	368	Missense	distal	-4	no	14.541	14.180	EPSD	ICGC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	Q9H211	CDT1	P24941	CDK2	S372	A378S	378	Missense	distal	6	no	14.541	14.546	EPSD	ICGC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	Q9H211	CDT1	P24941	CDK2	S391	P389H	389	Missense	proximal	-2	no	13.572	12.562	EPSD	ICGC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	Q9H211	CDT1	P24941	CDK2	S391	P395T	395	Missense	distal	4	no	13.572	13.855	EPSD	ICGC;COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	Q9H211	CDT1	P24941	CDK2	S394	P389H	389	Missense	distal	-5	no	15.927	15.974	EPSD	ICGC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	Q9H211	CDT1	P24941	CDK2	S394	P395T	395	Missense	proximal	1	no	15.927	5.969	EPSD	ICGC;COSMIC	8.148	Loss
CMGC_CDK_CDK2_CDK2_ST	Q9H211	CDT1	P24941	CDK2	T402	T406P	406	Missense	distal	4	no	14.160	13.877	EPSD	ICGC;COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	Q9H211	CDT1	P24941	CDK2	T402	P395T	395	Missense	distal	-7	no	14.160	14.157	EPSD	ICGC;COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	Q9H211	CDT1	P24941	CDK2	T402	A405S	405	Missense	distal	3	no	14.160	14.706	EPSD	ICGC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	Q9H211	CDT1	P24941	CDK2	T406	T406P	406	Missense	central	0	yes	12.369	0.000	EPSD	ICGC;COSMIC	8.148	Loss
CMGC_CDK_CDK2_CDK2_ST	Q9H211	CDT1	P24941	CDK2	T406	A405S	405	Missense	proximal	-1	no	12.369	12.168	EPSD	ICGC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	Q9H211	CDT1	P24941	CDK2	S411	T406P	406	Missense	distal	-5	no	12.954	12.955	EPSD	ICGC;COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	P25205	MCM3	P24941	CDK2	S333	R336Q	336	Missense	distal	3	no	8.718	6.975	EPSD	ICGC	8.148	Loss
CMGC_CDK_CDK2_CDK2_ST	O75179	ANKRD17	P24941	CDK2	S19	V26L	26	Missense	distal	7	no	14.227	13.999	EPSD	ICGC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	O75179	ANKRD17	P24941	CDK2	S19	T12M	12	Missense	distal	-7	no	14.227	14.731	EPSD	ICGC;COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	O75179	ANKRD17	P24941	CDK2	S50	R46H	46	Missense	distal	-4	no	10.411	10.050	EPSD	ICGC;COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	O75179	ANKRD17	P24941	CDK2	S50	M54T	54	Missense	distal	4	no	10.411	11.114	EPSD	ICGC;COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	O75179	ANKRD17	P24941	CDK2	S156	A162T	162	Missense	distal	6	no	8.165	8.177	EPSD	ICGC;COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	O75179	ANKRD17	P24941	CDK2	S156	L155V	155	Missense	proximal	-1	no	8.165	8.301	EPSD	ICGC;COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	O75179	ANKRD17	P24941	CDK2	S156	K152R	152	Missense	distal	-4	no	8.165	8.003	EPSD	ICGC;COSMIC	8.148	Loss
CMGC_CDK_CDK2_CDK2_ST	O75179	ANKRD17	P24941	CDK2	S469	A475D	475	Missense	distal	6	no	17.970	17.959	EPSD	ICGC;COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	O75179	ANKRD17	P24941	CDK2	S469	F467S	467	Missense	proximal	-2	no	17.970	18.432	EPSD	ICGC;COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	O75179	ANKRD17	P24941	CDK2	S792	A790T	790	Missense	proximal	-2	no	8.474	8.424	EPSD	ICGC;COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	O75179	ANKRD17	P24941	CDK2	T1287	H1280N	1280	Missense	distal	-7	no	13.356	13.151	EPSD	ICGC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	O75179	ANKRD17	P24941	CDK2	T1287	E1291D	1291	Missense	distal	4	no	13.356	13.274	EPSD	ICGC;COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	O75179	ANKRD17	P24941	CDK2	T1287	K1283R	1283	Missense	distal	-4	no	13.356	13.194	EPSD	ICGC;COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	O75179	ANKRD17	P24941	CDK2	T1577	Q1582E	1582	Missense	distal	5	no	12.062	12.181	EPSD	ICGC;COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	O75179	ANKRD17	P24941	CDK2	S1639	T1645A	1645	Missense	distal	6	no	11.890	11.878	EPSD	ICGC;COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	O75179	ANKRD17	P24941	CDK2	S1639	R1633H	1633	Missense	distal	-6	no	11.890	11.892	EPSD	ICGC;COSMIC;GDSC;CCLE	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	O75179	ANKRD17	P24941	CDK2	S1639	K1634E	1634	Missense	distal	-5	no	11.890	11.925	EPSD	ICGC;COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	O75179	ANKRD17	P24941	CDK2	S1696	S1700T	1700	Missense	distal	4	no	12.818	13.088	EPSD	ICGC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	O75179	ANKRD17	P24941	CDK2	S1991	S1993Y	1993	Missense	proximal	2	no	12.162	12.153	EPSD	ICGC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	O75179	ANKRD17	P24941	CDK2	S1991	G1987W	1987	Missense	distal	-4	no	12.162	11.479	EPSD	ICGC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	O75179	ANKRD17	P24941	CDK2	T2279	S2275Y	2275	Missense	distal	-4	no	10.431	10.542	EPSD	ICGC;COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	O75179	ANKRD17	P24941	CDK2	S2318	P2311T	2311	Missense	distal	-7	no	10.816	10.813	EPSD	ICGC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	O14757	CHEK1	P24941	CDK2	S286	V283L	283	Missense	distal	-3	no	12.386	12.172	PhosphoSitePlus;EPSD	ICGC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	O14757	CHEK1	P24941	CDK2	S301	S307Y	307	Missense	distal	6	no	16.125	16.116	EPSD;PhosphoSitePlus	ICGC;COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	O14757	CHEK1	P24941	CDK2	S331	L338S	338	Missense	distal	7	no	13.309	13.127	EPSD	ICGC;COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	O14757	CHEK1	P24941	CDK2	T362	G364V	364	Missense	proximal	2	no	11.394	11.399	EPSD	ICGC;COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	Q5JTZ9	AARS2	P24941	CDK2	T670	L677I	677	Missense	distal	7	no	14.019	14.046	EPSD	ICGC;COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	Q5JTZ9	AARS2	P24941	CDK2	T673	L677I	677	Missense	distal	4	no	14.099	13.959	PhosphoSitePlus	ICGC;COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	Q14202	ZMYM3	P24941	CDK2	S8	F10L	10	Missense	proximal	2	no	10.302	9.945	EPSD	ICGC;COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	Q14202	ZMYM3	P24941	CDK2	S51	A46P	46	Missense	distal	-5	no	15.483	15.458	EPSD	ICGC;COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	Q14202	ZMYM3	P24941	CDK2	S51	A56D	56	Missense	distal	5	no	15.483	15.647	EPSD	ICGC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	Q14202	ZMYM3	P24941	CDK2	S51	G49V	49	Missense	proximal	-2	no	15.483	15.576	EPSD	ICGC;COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	Q14202	ZMYM3	P24941	CDK2	S54	A56D	56	Missense	proximal	2	no	8.853	8.825	EPSD	ICGC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	Q14202	ZMYM3	P24941	CDK2	S54	G49V	49	Missense	distal	-5	no	8.853	8.804	EPSD	ICGC;COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	Q14202	ZMYM3	P24941	CDK2	T62	A56D	56	Missense	distal	-6	no	15.713	15.712	EPSD	ICGC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	Q14202	ZMYM3	P24941	CDK2	T62	T62N	62	Missense	central	0	yes	15.713	0.000	EPSD	ICGC	8.148	Loss
CMGC_CDK_CDK2_CDK2_ST	Q14202	ZMYM3	P24941	CDK2	S91	P92S	92	Missense	proximal	1	no	16.805	5.539	EPSD	ICGC	8.148	Loss
CMGC_CDK_CDK2_CDK2_ST	Q14202	ZMYM3	P24941	CDK2	S148	E142D	142	Missense	distal	-6	no	13.911	13.907	EPSD	ICGC;COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	Q14202	ZMYM3	P24941	CDK2	S148	P149L	149	Missense	proximal	1	no	13.911	4.090	EPSD	ICGC;COSMIC	8.148	Loss
CMGC_CDK_CDK2_CDK2_ST	Q14202	ZMYM3	P24941	CDK2	S148	P155T	155	Missense	distal	7	no	13.911	13.607	EPSD	ICGC;COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	Q14202	ZMYM3	P24941	CDK2	S148	A145T	145	Missense	distal	-3	no	13.911	13.930	EPSD	ICGC;COSMIC;CCLE	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	Q14202	ZMYM3	P24941	CDK2	S154	P149L	149	Missense	distal	-5	no	11.857	11.869	EPSD	ICGC;COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	Q14202	ZMYM3	P24941	CDK2	S154	P155T	155	Missense	proximal	1	no	11.857	1.900	EPSD	ICGC;COSMIC	8.148	Loss
CMGC_CDK_CDK2_CDK2_ST	Q14202	ZMYM3	P24941	CDK2	S186	P184S	184	Missense	proximal	-2	no	13.368	12.716	EPSD	ICGC;COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	Q14202	ZMYM3	P24941	CDK2	S186	P184Q	184	Missense	proximal	-2	no	13.368	12.801	EPSD	ICGC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	Q14202	ZMYM3	P24941	CDK2	S186	Q183K	183	Missense	distal	-3	no	13.368	13.269	EPSD	ICGC;COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	Q14202	ZMYM3	P24941	CDK2	S186	P190Q	190	Missense	distal	4	no	13.368	13.429	EPSD	ICGC;COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	Q14202	ZMYM3	P24941	CDK2	S192	P190Q	190	Missense	proximal	-2	no	13.959	13.392	EPSD	ICGC;COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	Q14202	ZMYM3	P24941	CDK2	S214	P219H	219	Missense	distal	5	no	11.689	11.767	EPSD	ICGC;COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	Q14202	ZMYM3	P24941	CDK2	S287	L292I	292	Missense	distal	5	no	12.458	12.511	EPSD	ICGC;COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	Q14202	ZMYM3	P24941	CDK2	S287	R289C	289	Missense	proximal	2	no	12.458	12.445	EPSD	ICGC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	Q14202	ZMYM3	P24941	CDK2	S464	G463E	463	Missense	proximal	-1	no	15.660	15.396	EPSD	ICGC;COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	P15336	ATF2	P24941	CDK2	S136	E130K	130	Missense	distal	-6	no	12.538	12.536	EPSD	ICGC;COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	P15336	ATF2	P24941	CDK2	T325	S321G	321	Missense	distal	-4	no	13.346	12.674	EPSD	ICGC;COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	P15336	ATF2	P24941	CDK2	S328	S321G	321	Missense	distal	-7	no	12.868	13.372	EPSD	ICGC;COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	P15336	ATF2	P24941	CDK2	T333	S340L	340	Missense	distal	7	no	11.689	11.871	EPSD	ICGC;COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	P15336	ATF2	P24941	CDK2	T333	Q337H	337	Missense	distal	4	no	11.689	11.390	EPSD	ICGC;COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	Q9UKM9	RALY	P24941	CDK2	S110	G111C	111	Missense	proximal	1	no	9.479	-2.138	EPSD	ICGC	8.148	Loss
CMGC_CDK_CDK2_CDK2_ST	Q9UKM9	RALY	P24941	CDK2	S135	R133G	133	Missense	proximal	-2	no	14.880	15.374	PhosphoSitePlus	ICGC;COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	Q9UKM9	RALY	P24941	CDK2	S135	R131L	131	Missense	distal	-4	no	14.880	15.065	PhosphoSitePlus	ICGC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	Q9UKM9	RALY	P24941	CDK2	S135	R133L	133	Missense	proximal	-2	no	14.880	15.892	PhosphoSitePlus	ICGC;COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	Q9UKM9	RALY	P24941	CDK2	S135	R133W	133	Missense	proximal	-2	no	14.880	14.381	PhosphoSitePlus	ICGC;COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	Q9UKM9	RALY	P24941	CDK2	S135	R141C	141	Missense	distal	6	no	14.880	14.883	PhosphoSitePlus	ICGC;COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	Q9UKM9	RALY	P24941	CDK2	S264	E265G	265	Missense	proximal	1	no	7.620	9.474	EPSD	ICGC;COSMIC	8.148	Gain
CMGC_CDK_CDK2_CDK2_ST	P78317	RNF4	P24941	CDK2	T26	T20A	20	Missense	distal	-6	no	13.011	13.010	PhosphoSitePlus;EPSD	ICGC;COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	P78317	RNF4	P24941	CDK2	T26	R21L	21	Missense	distal	-5	no	13.011	12.976	PhosphoSitePlus;EPSD	ICGC;COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	P78317	RNF4	P24941	CDK2	T26	A33S	33	Missense	distal	7	no	13.011	12.475	PhosphoSitePlus;EPSD	ICGC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	P78317	RNF4	P24941	CDK2	T112	H111N	111	Missense	proximal	-1	no	14.391	14.199	EPSD;PhosphoSitePlus	ICGC;COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	P38936	CDKN1A	P24941	CDK2	T57	D52N	52	Missense	distal	-5	no	15.802	15.764	EPSD	ICGC;COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	P38936	CDKN1A	P24941	CDK2	T57	E56D	56	Missense	proximal	-1	no	15.802	15.773	EPSD	ICGC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	P38936	CDKN1A	P24941	CDK2	T57	F51V	51	Missense	distal	-6	no	15.802	15.800	EPSD	ICGC;COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	P38936	CDKN1A	P24941	CDK2	T80	R86Q	86	Missense	distal	6	no	9.228	9.250	EPSD	ICGC;COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	P38936	CDKN1A	P24941	CDK2	S130	P131T	131	Missense	proximal	1	no	14.015	4.058	PhosphoSitePlus	ICGC;COSMIC	8.148	Loss
CMGC_CDK_CDK2_CDK2_ST	P38936	CDKN1A	P24941	CDK2	S130	P131Q	131	Missense	proximal	1	no	14.015	6.103	PhosphoSitePlus	ICGC;COSMIC	8.148	Loss
CMGC_CDK_CDK2_CDK2_ST	P38936	CDKN1A	P24941	CDK2	S130	G129W	129	Missense	proximal	-1	no	14.015	14.091	PhosphoSitePlus	ICGC;COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	Q8WYH8	ING5	P24941	CDK2	S57	P58L	58	Missense	proximal	1	no	12.411	2.590	EPSD	ICGC	8.148	Loss
CMGC_CDK_CDK2_CDK2_ST	Q8WYH8	ING5	P24941	CDK2	S118	G125R	125	Missense	distal	7	no	8.876	8.695	EPSD	ICGC;COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	Q8WYH8	ING5	P24941	CDK2	S123	G127V	127	Missense	distal	4	no	8.478	8.825	EPSD	ICGC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	Q8WYH8	ING5	P24941	CDK2	S123	G125R	125	Missense	proximal	2	no	8.478	8.519	EPSD	ICGC;COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	Q8WYH8	ING5	P24941	CDK2	T152	K157N	157	Missense	distal	5	no	16.833	16.990	PhosphoSitePlus	ICGC;COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	Q99607	ELF4	P24941	CDK2	S188	T191N	191	Missense	distal	3	no	12.678	12.230	EPSD	ICGC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	Q99607	ELF4	P24941	CDK2	S641	S641P	641	Missense	central	0	yes	16.080	0.000	EPSD	ICGC	8.148	Loss
CMGC_CDK_CDK2_CDK2_ST	Q99607	ELF4	P24941	CDK2	S641	S636R	636	Missense	distal	-5	no	16.080	16.171	EPSD	ICGC;COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	Q99607	ELF4	P24941	CDK2	T643	S641P	641	Missense	proximal	-2	no	16.397	17.049	PhosphoSitePlus;EPSD	ICGC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	Q99607	ELF4	P24941	CDK2	T643	S636R	636	Missense	distal	-7	no	16.397	16.921	PhosphoSitePlus;EPSD	ICGC;COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	Q99607	ELF4	P24941	CDK2	S648	S641P	641	Missense	distal	-7	no	14.494	14.674	EPSD;PhosphoSitePlus	ICGC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	P50570	DNM2	P24941	CDK2	S116	P119L	119	Missense	distal	3	no	12.816	12.432	EPSD	ICGC;COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	P50570	DNM2	P24941	CDK2	S126	V124L	124	Missense	proximal	-2	no	16.601	17.027	EPSD	ICGC;COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	P50570	DNM2	P24941	CDK2	S126	P119L	119	Missense	distal	-7	no	16.601	16.607	EPSD	ICGC;COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	P50570	DNM2	P24941	CDK2	T404	T404N	404	Missense	central	0	yes	16.089	0.000	EPSD	ICGC;COSMIC	8.148	Loss
CMGC_CDK_CDK2_CDK2_ST	P50570	DNM2	P24941	CDK2	T404	E410K	410	Missense	distal	6	no	16.089	16.101	EPSD	ICGC;COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	P50570	DNM2	P24941	CDK2	T404	R399S	399	Missense	distal	-5	no	16.089	15.998	EPSD	ICGC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	P50570	DNM2	P24941	CDK2	T404	P405L	405	Missense	proximal	1	no	16.089	6.269	EPSD	ICGC;COSMIC;GDSC;CCLE	8.148	Loss
CMGC_CDK_CDK2_CDK2_ST	P50570	DNM2	P24941	CDK2	T404	P405H	405	Missense	proximal	1	no	16.089	9.331	EPSD	ICGC;COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	P50570	DNM2	P24941	CDK2	T404	G401R	401	Missense	distal	-3	no	16.089	16.175	EPSD	ICGC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	P50570	DNM2	P24941	CDK2	T746	T741N	741	Missense	distal	-5	no	11.528	11.548	EPSD	ICGC;COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	P50570	DNM2	P24941	CDK2	S762	S759I	759	Missense	distal	-3	no	8.494	8.419	EPSD	ICGC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	P50570	DNM2	P24941	CDK2	S764	P771Q	771	Missense	distal	7	no	14.419	14.264	PhosphoSitePlus	ICGC;COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	P50570	DNM2	P24941	CDK2	S764	S759I	759	Missense	distal	-5	no	14.419	14.503	PhosphoSitePlus	ICGC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	P50570	DNM2	P24941	CDK2	T766	P771Q	771	Missense	distal	5	no	13.426	13.386	EPSD	ICGC;COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	P50570	DNM2	P24941	CDK2	T766	S759I	759	Missense	distal	-7	no	13.426	13.801	EPSD	ICGC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	Q05209	PTPN12	P24941	CDK2	S19	P20H	20	Missense	proximal	1	no	12.249	5.490	PhosphoSitePlus	ICGC;COSMIC	8.148	Loss
CMGC_CDK_CDK2_CDK2_ST	Q05209	PTPN12	P24941	CDK2	S19	R13S	13	Missense	distal	-6	no	12.249	12.246	PhosphoSitePlus	ICGC;COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	Q05209	PTPN12	P24941	CDK2	T81	Y88F	88	Missense	distal	7	no	12.706	13.138	EPSD	ICGC;COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	Q05209	PTPN12	P24941	CDK2	T81	Q84H	84	Missense	distal	3	no	12.706	13.753	EPSD	ICGC;COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	Q05209	PTPN12	P24941	CDK2	T81	D85G	85	Missense	distal	4	no	12.706	12.651	EPSD	ICGC;COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	Q05209	PTPN12	P24941	CDK2	T81	V75A	75	Missense	distal	-6	no	12.706	12.703	EPSD	ICGC;COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	Q05209	PTPN12	P24941	CDK2	T81	R74L	74	Missense	distal	-7	no	12.706	12.368	EPSD	ICGC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	Q05209	PTPN12	P24941	CDK2	T569	S567T	567	Missense	proximal	-2	no	13.363	13.981	EPSD	ICGC;COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	Q05209	PTPN12	P24941	CDK2	T569	Q575H	575	Missense	distal	6	no	13.363	13.352	EPSD	ICGC;COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	Q05209	PTPN12	P24941	CDK2	S571	S567T	567	Missense	distal	-4	no	14.227	14.039	EPSD	ICGC;COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	Q05209	PTPN12	P24941	CDK2	S571	Q575H	575	Missense	distal	4	no	14.227	13.928	EPSD	ICGC;COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	Q05209	PTPN12	P24941	CDK2	T574	Q575H	575	Missense	proximal	1	no	7.196	8.350	EPSD	ICGC;COSMIC	8.148	Gain
CMGC_CDK_CDK2_CDK2_ST	Q05209	PTPN12	P24941	CDK2	T578	Q575H	575	Missense	distal	-3	no	15.168	15.256	EPSD	ICGC;COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	Q05209	PTPN12	P24941	CDK2	T618	N623H	623	Missense	distal	5	no	8.697	8.672	EPSD	ICGC;COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	Q15788	NCOA1	P24941	CDK2	S16	P23S	23	Missense	distal	7	no	8.173	8.021	EPSD	ICGC;COSMIC	8.148	Loss
CMGC_CDK_CDK2_CDK2_ST	Q15788	NCOA1	P24941	CDK2	S16	P14T	14	Missense	proximal	-2	no	8.173	8.140	EPSD	ICGC;COSMIC;CCLE	8.148	Loss
CMGC_CDK_CDK2_CDK2_ST	Q15788	NCOA1	P24941	CDK2	S22	P23S	23	Missense	proximal	1	no	13.198	1.932	EPSD;PhosphoSitePlus	ICGC;COSMIC	8.148	Loss
CMGC_CDK_CDK2_CDK2_ST	Q15788	NCOA1	P24941	CDK2	S22	A28S	28	Missense	distal	6	no	13.198	13.204	EPSD;PhosphoSitePlus	ICGC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	Q15788	NCOA1	P24941	CDK2	S22	D25Y	25	Missense	distal	3	no	13.198	14.266	EPSD;PhosphoSitePlus	ICGC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	Q15788	NCOA1	P24941	CDK2	S192	M199I	199	Missense	distal	7	no	8.752	8.264	EPSD	ICGC;COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	Q15788	NCOA1	P24941	CDK2	S395	R402P	402	Missense	distal	7	no	15.481	14.991	EPSD;PhosphoSitePlus	ICGC;COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	Q15788	NCOA1	P24941	CDK2	S395	P388H	388	Missense	distal	-7	no	15.481	15.604	EPSD;PhosphoSitePlus	ICGC;COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	Q15788	NCOA1	P24941	CDK2	S395	R402H	402	Missense	distal	7	no	15.481	15.122	EPSD;PhosphoSitePlus	ICGC;COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	Q15788	NCOA1	P24941	CDK2	S517	I512V	512	Missense	distal	-5	no	14.452	14.444	EPSD	ICGC;COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	Q15788	NCOA1	P24941	CDK2	S569	S571I	571	Missense	proximal	2	no	15.094	15.005	EPSD;PhosphoSitePlus	ICGC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	Q15788	NCOA1	P24941	CDK2	S598	D599H	599	Missense	proximal	1	no	6.735	8.220	EPSD	ICGC;COSMIC	8.148	Gain
CMGC_CDK_CDK2_CDK2_ST	Q15788	NCOA1	P24941	CDK2	S603	D599H	599	Missense	distal	-4	no	8.801	7.670	EPSD	ICGC;COSMIC	8.148	Loss
CMGC_CDK_CDK2_CDK2_ST	Q15788	NCOA1	P24941	CDK2	S698	E696D	696	Missense	proximal	-2	no	11.902	12.882	EPSD	ICGC;COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	Q15788	NCOA1	P24941	CDK2	S698	D701Y	701	Missense	distal	3	no	11.902	12.970	EPSD	ICGC;COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	Q15788	NCOA1	P24941	CDK2	T763	E757D	757	Missense	distal	-6	no	12.212	12.208	EPSD	ICGC;COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	Q15788	NCOA1	P24941	CDK2	T789	P788Q	788	Missense	proximal	-1	no	14.593	14.285	EPSD;PhosphoSitePlus	ICGC;COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	Q15788	NCOA1	P24941	CDK2	T979	A978S	978	Missense	proximal	-1	no	12.496	12.295	EPSD;PhosphoSitePlus	ICGC;COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	Q15788	NCOA1	P24941	CDK2	T979	A978T	978	Missense	proximal	-1	no	12.496	12.503	EPSD;PhosphoSitePlus	ICGC;COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	Q15788	NCOA1	P24941	CDK2	S997	L1004F	1004	Missense	distal	7	no	11.843	12.514	EPSD;PhosphoSitePlus	ICGC;COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	Q15788	NCOA1	P24941	CDK2	S997	A1002S	1002	Missense	distal	5	no	11.843	11.732	EPSD;PhosphoSitePlus	ICGC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	Q15788	NCOA1	P24941	CDK2	S997	P998S	998	Missense	proximal	1	no	11.843	0.577	EPSD;PhosphoSitePlus	ICGC	8.148	Loss
CMGC_CDK_CDK2_CDK2_ST	Q15788	NCOA1	P24941	CDK2	S999	L1004F	1004	Missense	distal	5	no	13.074	13.252	EPSD	ICGC;COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	Q15788	NCOA1	P24941	CDK2	S999	S1006I	1006	Missense	distal	7	no	13.074	13.283	EPSD	ICGC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	Q15788	NCOA1	P24941	CDK2	S999	A1002S	1002	Missense	distal	3	no	13.074	13.620	EPSD	ICGC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	Q15788	NCOA1	P24941	CDK2	S999	P998S	998	Missense	proximal	-1	no	13.074	12.603	EPSD	ICGC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	Q15788	NCOA1	P24941	CDK2	S1006	L1004F	1004	Missense	proximal	-2	no	13.477	12.588	EPSD;PhosphoSitePlus	ICGC;COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	Q15788	NCOA1	P24941	CDK2	S1006	G1010C	1010	Missense	distal	4	no	13.477	12.850	EPSD;PhosphoSitePlus	ICGC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	Q15788	NCOA1	P24941	CDK2	S1006	M1011I	1011	Missense	distal	5	no	13.477	13.262	EPSD;PhosphoSitePlus	ICGC;COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	Q15788	NCOA1	P24941	CDK2	S1006	S1006I	1006	Missense	central	0	yes	13.477	0.000	EPSD;PhosphoSitePlus	ICGC	8.148	Loss
CMGC_CDK_CDK2_CDK2_ST	Q15788	NCOA1	P24941	CDK2	S1006	V1012F	1012	Missense	distal	6	no	13.477	13.460	EPSD;PhosphoSitePlus	ICGC;COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	Q15788	NCOA1	P24941	CDK2	S1006	A1002S	1002	Missense	distal	-4	no	13.477	13.890	EPSD;PhosphoSitePlus	ICGC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	Q15788	NCOA1	P24941	CDK2	S1006	G1010V	1010	Missense	distal	4	no	13.477	13.824	EPSD;PhosphoSitePlus	ICGC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	Q15788	NCOA1	P24941	CDK2	S1006	P1007S	1007	Missense	proximal	1	no	13.477	2.211	EPSD;PhosphoSitePlus	ICGC	8.148	Loss
CMGC_CDK_CDK2_CDK2_ST	Q15788	NCOA1	P24941	CDK2	T1026	Q1024E	1024	Missense	proximal	-2	no	13.395	12.847	EPSD;PhosphoSitePlus	ICGC;COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	Q15788	NCOA1	P24941	CDK2	T1026	T1020M	1020	Missense	distal	-6	no	13.395	13.403	EPSD;PhosphoSitePlus	ICGC;COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	Q15788	NCOA1	P24941	CDK2	T1026	P1027L	1027	Missense	proximal	1	no	13.395	3.574	EPSD;PhosphoSitePlus	ICGC	8.148	Loss
CMGC_CDK_CDK2_CDK2_ST	Q15788	NCOA1	P24941	CDK2	T1026	R1029Q	1029	Missense	distal	3	no	13.395	11.652	EPSD;PhosphoSitePlus	ICGC;COSMIC;GDSC;CCLE	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	Q15788	NCOA1	P24941	CDK2	S1033	G1035D	1035	Missense	proximal	2	no	15.362	15.241	EPSD;PhosphoSitePlus	ICGC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	Q15788	NCOA1	P24941	CDK2	S1033	R1029Q	1029	Missense	distal	-4	no	15.362	15.386	EPSD;PhosphoSitePlus	ICGC;COSMIC;GDSC;CCLE	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	Q15788	NCOA1	P24941	CDK2	T1099	P1102T	1102	Missense	distal	3	no	11.778	11.664	EPSD	ICGC;COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	Q15788	NCOA1	P24941	CDK2	T1179	Y1173F	1173	Missense	distal	-6	no	13.578	13.582	EPSD;PhosphoSitePlus	ICGC;COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	Q15788	NCOA1	P24941	CDK2	T1179	S1185C	1185	Missense	distal	6	no	13.578	13.563	EPSD;PhosphoSitePlus	ICGC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	Q15788	NCOA1	P24941	CDK2	T1179	P1186S	1186	Missense	distal	7	no	13.578	13.426	EPSD;PhosphoSitePlus	ICGC;COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	Q15788	NCOA1	P24941	CDK2	T1179	G1174C	1174	Missense	distal	-5	no	13.578	13.579	EPSD;PhosphoSitePlus	ICGC;COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	Q15788	NCOA1	P24941	CDK2	S1185	S1185C	1185	Missense	central	0	yes	14.076	0.000	EPSD;PhosphoSitePlus	ICGC	8.148	Loss
CMGC_CDK_CDK2_CDK2_ST	Q15788	NCOA1	P24941	CDK2	S1185	P1186S	1186	Missense	proximal	1	no	14.076	2.810	EPSD;PhosphoSitePlus	ICGC;COSMIC	8.148	Loss
CMGC_CDK_CDK2_CDK2_ST	Q15788	NCOA1	P24941	CDK2	S1250	P1251S	1251	Missense	proximal	1	no	10.963	-0.303	EPSD;PhosphoSitePlus	ICGC	8.148	Loss
CMGC_CDK_CDK2_CDK2_ST	Q15788	NCOA1	P24941	CDK2	S1250	L1249I	1249	Missense	proximal	-1	no	10.963	11.125	EPSD;PhosphoSitePlus	ICGC;COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	Q15788	NCOA1	P24941	CDK2	T1271	Q1278H	1278	Missense	distal	7	no	10.137	10.423	EPSD;PhosphoSitePlus	ICGC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	Q15788	NCOA1	P24941	CDK2	S1279	Q1278H	1278	Missense	proximal	-1	no	15.314	15.741	EPSD;PhosphoSitePlus	ICGC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	Q15788	NCOA1	P24941	CDK2	T1426	T1421M	1421	Missense	distal	-5	no	12.764	12.872	EPSD;PhosphoSitePlus	ICGC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	P23771	GATA3	P24941	CDK2	S110	G104A	104	Missense	distal	-6	no	11.995	11.991	EPSD	ICGC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	P23771	GATA3	P24941	CDK2	T156	H149P	149	Missense	distal	-7	no	16.652	16.529	PhosphoSitePlus	ICGC;COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	P23771	GATA3	P24941	CDK2	T156	F153S	153	Missense	distal	-3	no	16.652	16.560	PhosphoSitePlus	ICGC;COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	P23771	GATA3	P24941	CDK2	T156	K159N	159	Missense	distal	3	no	16.652	13.382	PhosphoSitePlus	ICGC;COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	P23771	GATA3	P24941	CDK2	S162	K159N	159	Missense	distal	-3	no	12.164	12.226	EPSD	ICGC;COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	P23771	GATA3	P24941	CDK2	S243	P236H	236	Missense	distal	-7	no	12.847	12.970	EPSD	ICGC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	P23771	GATA3	P24941	CDK2	S243	S238I	238	Missense	distal	-5	no	12.847	12.930	EPSD	ICGC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	P23771	GATA3	P24941	CDK2	T271	R275Q	275	Missense	distal	4	no	12.414	12.595	EPSD	ICGC;COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	P23771	GATA3	P24941	CDK2	T271	G278D	278	Missense	distal	7	no	12.414	12.430	EPSD	ICGC;COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	P23771	GATA3	P24941	CDK2	T271	R275W	275	Missense	distal	4	no	12.414	12.054	EPSD	ICGC;COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	P23771	GATA3	P24941	CDK2	T271	G278V	278	Missense	distal	7	no	12.414	12.002	EPSD	ICGC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	P23771	GATA3	P24941	CDK2	T271	G278C	278	Missense	distal	7	no	12.414	12.385	EPSD	ICGC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	P23771	GATA3	P24941	CDK2	T271	G278S	278	Missense	distal	7	no	12.414	11.592	EPSD	ICGC;COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	P23771	GATA3	P24941	CDK2	T271	A268E	268	Missense	distal	-3	no	12.414	12.647	EPSD	ICGC;COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	P23771	GATA3	P24941	CDK2	T271	T271N	271	Missense	central	0	yes	12.414	0.000	EPSD	ICGC;COSMIC	8.148	Loss
CMGC_CDK_CDK2_CDK2_ST	P23771	GATA3	P24941	CDK2	T271	A268T	268	Missense	distal	-3	no	12.414	12.433	EPSD	ICGC;COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	P23771	GATA3	P24941	CDK2	T271	R276Q	276	Missense	distal	5	no	12.414	12.267	EPSD	ICGC;COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	Q15554	TERF2	P24941	CDK2	S53	R59S	59	Missense	distal	6	no	9.258	9.276	EPSD	ICGC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	Q9UGP5	POLL	P24941	CDK2	S167	L166V	166	Missense	proximal	-1	no	13.863	13.999	EPSD;PhosphoSitePlus	ICGC;COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	Q9UGP5	POLL	P24941	CDK2	S177	A182E	182	Missense	distal	5	no	14.528	14.597	PhosphoSitePlus;EPSD	ICGC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	Q9UGP5	POLL	P24941	CDK2	T553	P554T	554	Missense	proximal	1	no	15.305	5.347	EPSD;PhosphoSitePlus	ICGC	8.148	Loss
CMGC_CDK_CDK2_CDK2_ST	Q9UGP5	POLL	P24941	CDK2	T553	P554S	554	Missense	proximal	1	no	15.305	4.039	EPSD;PhosphoSitePlus	ICGC	8.148	Loss
CMGC_CDK_CDK2_CDK2_ST	O94761	RECQL4	P24941	CDK2	S89	Q91K	91	Missense	proximal	2	no	15.429	15.229	EPSD;PhosphoSitePlus	ICGC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	O94761	RECQL4	P24941	CDK2	S89	R96L	96	Missense	distal	7	no	15.429	14.970	EPSD;PhosphoSitePlus	ICGC;COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	O94761	RECQL4	P24941	CDK2	T93	Q91K	91	Missense	proximal	-2	no	17.099	17.151	EPSD	ICGC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	O94761	RECQL4	P24941	CDK2	T93	R96L	96	Missense	distal	3	no	17.099	14.997	EPSD	ICGC;COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	O94761	RECQL4	P24941	CDK2	S251	S257T	257	Missense	distal	6	no	14.684	14.690	PhosphoSitePlus;EPSD	ICGC;COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	O94761	RECQL4	P24941	CDK2	S251	S246T	246	Missense	distal	-5	no	14.684	14.727	PhosphoSitePlus;EPSD	ICGC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	O94761	RECQL4	P24941	CDK2	S251	S251R	251	Missense	central	0	yes	14.684	0.000	PhosphoSitePlus;EPSD	ICGC;COSMIC	8.148	Loss
CMGC_CDK_CDK2_CDK2_ST	Q9NSV4	DIAPH3	P24941	CDK2	S48	Q42K	42	Missense	distal	-6	no	8.475	8.471	EPSD	ICGC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	Q9NSV4	DIAPH3	P24941	CDK2	S48	P41S	41	Missense	distal	-7	no	8.475	8.295	EPSD	ICGC;COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	Q9NSV4	DIAPH3	P24941	CDK2	S48	E55D	55	Missense	distal	7	no	8.475	9.117	EPSD	ICGC;COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	Q9NSV4	DIAPH3	P24941	CDK2	S48	G54W	54	Missense	distal	6	no	8.475	8.462	EPSD	ICGC;COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	Q9NSV4	DIAPH3	P24941	CDK2	S607	P614H	614	Missense	distal	7	no	8.173	8.305	EPSD	ICGC;COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	Q9NSV4	DIAPH3	P24941	CDK2	S624	Q622K	622	Missense	proximal	-2	no	14.198	14.251	EPSD	ICGC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	Q9NSV4	DIAPH3	P24941	CDK2	S624	L619F	619	Missense	distal	-5	no	14.198	14.259	EPSD	ICGC;GDSC;CCLE	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	Q9NSV4	DIAPH3	P24941	CDK2	S1093	P1099H	1099	Missense	distal	6	no	14.173	14.169	EPSD	ICGC;COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	Q9NSV4	DIAPH3	P24941	CDK2	S1093	D1087G	1087	Missense	distal	-6	no	14.173	14.178	EPSD	ICGC;COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	Q9NSV4	DIAPH3	P24941	CDK2	S1093	P1094Q	1094	Missense	proximal	1	no	14.173	6.262	EPSD	ICGC;COSMIC	8.148	Loss
CMGC_CDK_CDK2_CDK2_ST	Q9NSV4	DIAPH3	P24941	CDK2	S1096	P1099H	1099	Missense	distal	3	no	10.135	11.157	EPSD	ICGC;COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	Q9NSV4	DIAPH3	P24941	CDK2	S1096	P1094Q	1094	Missense	proximal	-2	no	10.135	9.568	EPSD	ICGC;COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	Q9NSV4	DIAPH3	P24941	CDK2	T1130	A1133T	1133	Missense	distal	3	no	13.879	14.277	EPSD	ICGC;COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	Q9NSV4	DIAPH3	P24941	CDK2	T1130	N1126K	1126	Missense	distal	-4	no	13.879	13.660	EPSD	ICGC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	P28324	ELK4	P24941	CDK2	S180	K178T	178	Missense	proximal	-2	no	12.829	13.310	EPSD	ICGC;COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	P28324	ELK4	P24941	CDK2	S180	K179T	179	Missense	proximal	-1	no	12.829	12.666	EPSD	ICGC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	P28324	ELK4	P24941	CDK2	T185	K178T	178	Missense	distal	-7	no	12.322	12.367	EPSD	ICGC;COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	P28324	ELK4	P24941	CDK2	T194	P199S	199	Missense	distal	5	no	14.015	13.914	EPSD;PhosphoSitePlus	ICGC;COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	P28324	ELK4	P24941	CDK2	S215	S209L	209	Missense	distal	-6	no	12.434	12.435	EPSD	ICGC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	P28324	ELK4	P24941	CDK2	S230	P231Q	231	Missense	proximal	1	no	12.406	4.494	EPSD	ICGC;COSMIC	8.148	Loss
CMGC_CDK_CDK2_CDK2_ST	P28324	ELK4	P24941	CDK2	S230	T227A	227	Missense	distal	-3	no	12.406	12.387	EPSD	ICGC;COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	P28324	ELK4	P24941	CDK2	S381	P388T	388	Missense	distal	7	no	14.446	14.143	EPSD	ICGC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	P28324	ELK4	P24941	CDK2	S381	P388Q	388	Missense	distal	7	no	14.446	14.292	EPSD	ICGC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	P28324	ELK4	P24941	CDK2	S381	W377L	377	Missense	distal	-4	no	14.446	15.389	EPSD	ICGC;COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	P28324	ELK4	P24941	CDK2	S381	A384S	384	Missense	distal	3	no	14.446	14.992	EPSD	ICGC;COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	P28324	ELK4	P24941	CDK2	S387	P388T	388	Missense	proximal	1	no	15.345	5.388	PhosphoSitePlus;EPSD	ICGC	8.148	Loss
CMGC_CDK_CDK2_CDK2_ST	P28324	ELK4	P24941	CDK2	S387	P388Q	388	Missense	proximal	1	no	15.345	7.434	PhosphoSitePlus;EPSD	ICGC	8.148	Loss
CMGC_CDK_CDK2_CDK2_ST	P28324	ELK4	P24941	CDK2	S387	G393C	393	Missense	distal	6	no	15.345	15.343	PhosphoSitePlus;EPSD	ICGC;COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	P28324	ELK4	P24941	CDK2	S387	A384S	384	Missense	distal	-3	no	15.345	15.499	PhosphoSitePlus;EPSD	ICGC;COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	P28324	ELK4	P24941	CDK2	T420	P418S	418	Missense	proximal	-2	no	13.564	12.912	EPSD	ICGC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	P28324	ELK4	P24941	CDK2	T420	G417R	417	Missense	distal	-3	no	13.564	13.649	EPSD	ICGC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	P28324	ELK4	P24941	CDK2	T420	G422C	422	Missense	proximal	2	no	13.564	13.592	EPSD	ICGC;COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	P28324	ELK4	P24941	CDK2	T420	P421T	421	Missense	proximal	1	no	13.564	3.606	EPSD	ICGC;COSMIC	8.148	Loss
CMGC_CDK_CDK2_CDK2_ST	P28324	ELK4	P24941	CDK2	T420	P423L	423	Missense	distal	3	no	13.564	13.180	EPSD	ICGC;COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	P28324	ELK4	P24941	CDK2	T420	P423Q	423	Missense	distal	3	no	13.564	13.539	EPSD	ICGC;COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	P28324	ELK4	P24941	CDK2	T420	T420A	420	Missense	central	0	yes	13.564	0.000	EPSD	ICGC	8.148	Loss
CMGC_CDK_CDK2_CDK2_ST	P28324	ELK4	P24941	CDK2	S425	P418S	418	Missense	distal	-7	no	16.192	16.012	EPSD	ICGC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	P28324	ELK4	P24941	CDK2	S425	G422C	422	Missense	distal	-3	no	16.192	16.191	EPSD	ICGC;COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	P28324	ELK4	P24941	CDK2	S425	P421T	421	Missense	distal	-4	no	16.192	16.358	EPSD	ICGC;COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	P28324	ELK4	P24941	CDK2	S425	P423L	423	Missense	proximal	-2	no	16.192	15.967	EPSD	ICGC;COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	P28324	ELK4	P24941	CDK2	S425	P423Q	423	Missense	proximal	-2	no	16.192	15.625	EPSD	ICGC;COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	P28324	ELK4	P24941	CDK2	S425	T420A	420	Missense	distal	-5	no	16.192	16.218	EPSD	ICGC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	P03372	ESR1	P24941	CDK2	S104	P99S	99	Missense	distal	-5	no	16.821	16.776	EPSD;PhosphoSitePlus	ICGC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	P03372	ESR1	P24941	CDK2	S104	S102N	102	Missense	proximal	-2	no	16.821	16.129	EPSD;PhosphoSitePlus	ICGC;COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	P03372	ESR1	P24941	CDK2	S104	N101S	101	Missense	distal	-3	no	16.821	16.895	EPSD;PhosphoSitePlus	ICGC;COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	P03372	ESR1	P24941	CDK2	S106	P99S	99	Missense	distal	-7	no	12.768	12.588	EPSD;PhosphoSitePlus	ICGC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	P03372	ESR1	P24941	CDK2	S106	S102N	102	Missense	distal	-4	no	12.768	12.552	EPSD;PhosphoSitePlus	ICGC;COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	P03372	ESR1	P24941	CDK2	S106	N101S	101	Missense	distal	-5	no	12.768	12.705	EPSD;PhosphoSitePlus	ICGC;COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	P03372	ESR1	P24941	CDK2	S106	H112P	112	Missense	distal	6	no	12.768	12.773	EPSD;PhosphoSitePlus	ICGC;COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	P03372	ESR1	P24941	CDK2	S118	H112P	112	Missense	distal	-6	no	12.997	12.994	PhosphoSitePlus;EPSD	ICGC;COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	P03372	ESR1	P24941	CDK2	S118	P114L	114	Missense	distal	-4	no	12.997	12.939	PhosphoSitePlus;EPSD	ICGC;COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	P03372	ESR1	P24941	CDK2	S294	R300L	300	Missense	distal	6	no	12.927	12.945	EPSD;PhosphoSitePlus	ICGC;COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	P03372	ESR1	P24941	CDK2	S294	R300S	300	Missense	distal	6	no	12.927	12.945	EPSD;PhosphoSitePlus	ICGC;COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	P03372	ESR1	P24941	CDK2	S294	R300H	300	Missense	distal	6	no	12.927	12.939	EPSD;PhosphoSitePlus	ICGC;COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	Q12778	FOXO1	P24941	CDK2	S279	A284D	284	Missense	distal	5	no	8.190	8.354	EPSD	ICGC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	Q12778	FOXO1	P24941	CDK2	S279	Q281K	281	Missense	proximal	2	no	8.190	7.990	EPSD	ICGC;COSMIC	8.148	Loss
CMGC_CDK_CDK2_CDK2_ST	Q12778	FOXO1	P24941	CDK2	S287	S293Y	293	Missense	distal	6	no	15.718	15.709	EPSD	ICGC;COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	Q12778	FOXO1	P24941	CDK2	S287	A284D	284	Missense	distal	-3	no	15.718	15.842	EPSD	ICGC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	Q12778	FOXO1	P24941	CDK2	S287	Q281K	281	Missense	distal	-6	no	15.718	15.715	EPSD	ICGC;COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	Q12778	FOXO1	P24941	CDK2	S290	S293Y	293	Missense	distal	3	no	8.968	8.188	EPSD	ICGC;COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	Q12778	FOXO1	P24941	CDK2	S290	A284D	284	Missense	distal	-6	no	8.968	8.967	EPSD	ICGC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	Q12778	FOXO1	P24941	CDK2	S298	S293Y	293	Missense	distal	-5	no	12.278	12.347	EPSD	ICGC;COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	Q12778	FOXO1	P24941	CDK2	S329	E334K	334	Missense	distal	5	no	11.834	11.701	EPSD	ICGC;COSMIC;CCLE	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	Q12778	FOXO1	P24941	CDK2	S329	G326V	326	Missense	distal	-3	no	11.834	11.874	EPSD	ICGC;COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	Q12778	FOXO1	P24941	CDK2	S383	P384T	384	Missense	proximal	1	no	15.642	5.684	EPSD	ICGC	8.148	Loss
CMGC_CDK_CDK2_CDK2_ST	Q12778	FOXO1	P24941	CDK2	S394	Q392K	392	Missense	proximal	-2	no	13.914	13.967	EPSD	ICGC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	Q12778	FOXO1	P24941	CDK2	T402	P403S	403	Missense	proximal	1	no	11.030	-0.236	EPSD	ICGC	8.148	Loss
CMGC_CDK_CDK2_CDK2_ST	Q12778	FOXO1	P24941	CDK2	T402	P409T	409	Missense	distal	7	no	11.030	10.726	EPSD	ICGC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	Q12778	FOXO1	P24941	CDK2	T402	P409Q	409	Missense	distal	7	no	11.030	10.875	EPSD	ICGC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	Q12778	FOXO1	P24941	CDK2	S416	P410Q	410	Missense	distal	-6	no	14.544	14.547	EPSD	ICGC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	Q12778	FOXO1	P24941	CDK2	S416	P409T	409	Missense	distal	-7	no	14.544	14.541	EPSD	ICGC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	Q12778	FOXO1	P24941	CDK2	S416	P409Q	409	Missense	distal	-7	no	14.544	14.501	EPSD	ICGC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	Q12778	FOXO1	P24941	CDK2	S470	D475E	475	Missense	distal	5	no	15.813	15.718	EPSD	ICGC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	Q12778	FOXO1	P24941	CDK2	S470	L465F	465	Missense	distal	-5	no	15.813	15.874	EPSD	ICGC;COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	Q12778	FOXO1	P24941	CDK2	T478	D475E	475	Missense	distal	-3	no	13.501	13.611	EPSD	ICGC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	Q12778	FOXO1	P24941	CDK2	T478	G483V	483	Missense	distal	5	no	13.501	13.342	EPSD	ICGC;COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	Q12778	FOXO1	P24941	CDK2	T649	S651R	651	Missense	proximal	2	no	8.347	8.439	EPSD	ICGC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	Q12778	FOXO1	P24941	CDK2	T649	T649A	649	Missense	central	0	yes	8.347	0.000	EPSD	ICGC	8.148	Loss
CMGC_CDK_CDK2_CDK2_ST	P12268	IMPDH2	P24941	CDK2	S122	L121I	121	Missense	proximal	-1	no	13.332	13.494	PhosphoSitePlus	ICGC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	P12268	IMPDH2	P24941	CDK2	S426	R429K	429	Missense	distal	3	no	7.984	8.973	EPSD	ICGC;COSMIC	8.148	Gain
CMGC_CDK_CDK2_CDK2_ST	O75533	SF3B1	P24941	CDK2	S97	Q100K	100	Missense	distal	3	no	7.086	9.819	EPSD	ICGC	8.148	Gain
CMGC_CDK_CDK2_CDK2_ST	O75533	SF3B1	P24941	CDK2	S129	I128F	128	Missense	proximal	-1	no	18.222	19.025	EPSD	ICGC;COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	O75533	SF3B1	P24941	CDK2	S129	I127T	127	Missense	proximal	-2	no	18.222	18.342	EPSD	ICGC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	O75533	SF3B1	P24941	CDK2	S129	H122N	122	Missense	distal	-7	no	18.222	18.017	EPSD	ICGC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	O75533	SF3B1	P24941	CDK2	S129	T125N	125	Missense	distal	-4	no	18.222	18.194	EPSD	ICGC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	O75533	SF3B1	P24941	CDK2	S129	M126I	126	Missense	distal	-3	no	18.222	17.873	EPSD	ICGC;COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	O75533	SF3B1	P24941	CDK2	S129	R132C	132	Missense	distal	3	no	18.222	11.858	EPSD	ICGC;COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	O75533	SF3B1	P24941	CDK2	T142	G140W	140	Missense	proximal	-2	no	14.904	13.912	EPSD;PhosphoSitePlus	ICGC;COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	O75533	SF3B1	P24941	CDK2	T207	D201N	201	Missense	distal	-6	no	14.375	14.376	EPSD	ICGC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	O75533	SF3B1	P24941	CDK2	T207	P212L	212	Missense	distal	5	no	14.375	14.415	EPSD	ICGC;COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	O75533	SF3B1	P24941	CDK2	T211	P212L	212	Missense	proximal	1	no	15.661	5.840	PhosphoSitePlus;EPSD	ICGC;COSMIC	8.148	Loss
CMGC_CDK_CDK2_CDK2_ST	O75533	SF3B1	P24941	CDK2	T235	R238S	238	Missense	distal	3	no	15.794	14.110	EPSD	ICGC;COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	O75533	SF3B1	P24941	CDK2	T235	T235K	235	Missense	central	0	yes	15.794	0.000	EPSD	ICGC	8.148	Loss
CMGC_CDK_CDK2_CDK2_ST	O75533	SF3B1	P24941	CDK2	T244	R238S	238	Missense	distal	-6	no	12.901	12.898	EPSD;PhosphoSitePlus	ICGC;COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	O75533	SF3B1	P24941	CDK2	T244	A247E	247	Missense	distal	3	no	12.901	14.035	EPSD;PhosphoSitePlus	ICGC;COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	O75533	SF3B1	P24941	CDK2	T248	A247E	247	Missense	proximal	-1	no	14.377	15.432	EPSD;PhosphoSitePlus	ICGC;COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	O75533	SF3B1	P24941	CDK2	T257	P262L	262	Missense	distal	5	no	15.238	15.277	EPSD	ICGC;COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	O75533	SF3B1	P24941	CDK2	S259	P262L	262	Missense	distal	3	no	8.642	8.259	EPSD	ICGC;COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	O75533	SF3B1	P24941	CDK2	T261	P262L	262	Missense	proximal	1	no	14.208	4.387	EPSD	ICGC;COSMIC	8.148	Loss
CMGC_CDK_CDK2_CDK2_ST	O75533	SF3B1	P24941	CDK2	T267	D272H	272	Missense	distal	5	no	15.272	15.176	EPSD	ICGC;COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	O75533	SF3B1	P24941	CDK2	T267	P262L	262	Missense	distal	-5	no	15.272	15.284	EPSD	ICGC;COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	O75533	SF3B1	P24941	CDK2	T273	D272H	272	Missense	proximal	-1	no	16.321	15.685	EPSD	ICGC;COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	O75533	SF3B1	P24941	CDK2	T278	D272H	272	Missense	distal	-6	no	16.046	16.051	EPSD	ICGC;COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	O75533	SF3B1	P24941	CDK2	T278	A284T	284	Missense	distal	6	no	16.046	16.058	EPSD	ICGC;COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	O75533	SF3B1	P24941	CDK2	T296	R289H	289	Missense	distal	-7	no	15.789	15.569	EPSD	ICGC;COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	O75533	SF3B1	P24941	CDK2	S308	R315L	315	Missense	distal	7	no	8.909	8.450	EPSD	ICGC;COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	O75533	SF3B1	P24941	CDK2	T313	R315L	315	Missense	proximal	2	no	17.125	16.859	EPSD;PhosphoSitePlus	ICGC;COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	O75533	SF3B1	P24941	CDK2	T326	A331D	331	Missense	distal	5	no	13.836	14.000	EPSD	ICGC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	O75533	SF3B1	P24941	CDK2	T326	P327L	327	Missense	proximal	1	no	13.836	4.015	EPSD	ICGC;COSMIC;CCLE	8.148	Loss
CMGC_CDK_CDK2_CDK2_ST	O75533	SF3B1	P24941	CDK2	T328	A331D	331	Missense	distal	3	no	11.537	10.235	EPSD	ICGC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	O75533	SF3B1	P24941	CDK2	T328	P327L	327	Missense	proximal	-1	no	11.537	11.357	EPSD	ICGC;COSMIC;CCLE	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	O75533	SF3B1	P24941	CDK2	T341	G347S	347	Missense	distal	6	no	15.136	15.148	EPSD	ICGC;COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	O75533	SF3B1	P24941	CDK2	T341	P342T	342	Missense	proximal	1	no	15.136	5.179	EPSD	ICGC;COSMIC	8.148	Loss
CMGC_CDK_CDK2_CDK2_ST	O75533	SF3B1	P24941	CDK2	S344	G347S	347	Missense	distal	3	no	8.064	8.199	EPSD	ICGC;COSMIC	8.148	Gain
CMGC_CDK_CDK2_CDK2_ST	O75533	SF3B1	P24941	CDK2	T350	G347S	347	Missense	distal	-3	no	11.465	11.457	EPSD	ICGC;COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	O75533	SF3B1	P24941	CDK2	T350	T354N	354	Missense	distal	4	no	11.465	11.162	EPSD	ICGC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	O75533	SF3B1	P24941	CDK2	T350	P351T	351	Missense	proximal	1	no	11.465	1.508	EPSD	ICGC;COSMIC	8.148	Loss
CMGC_CDK_CDK2_CDK2_ST	O75533	SF3B1	P24941	CDK2	T354	G347S	347	Missense	distal	-7	no	19.286	18.782	EPSD;PhosphoSitePlus	ICGC;COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	O75533	SF3B1	P24941	CDK2	T354	T354N	354	Missense	central	0	yes	19.286	0.000	EPSD;PhosphoSitePlus	ICGC	8.148	Loss
CMGC_CDK_CDK2_CDK2_ST	O75533	SF3B1	P24941	CDK2	T354	P351T	351	Missense	distal	-3	no	19.286	19.247	EPSD;PhosphoSitePlus	ICGC;COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	O75533	SF3B1	P24941	CDK2	T358	T354N	354	Missense	distal	-4	no	13.094	13.066	EPSD	ICGC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	O75533	SF3B1	P24941	CDK2	T358	A364D	364	Missense	distal	6	no	13.094	13.083	EPSD	ICGC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	O75533	SF3B1	P24941	CDK2	T358	P351T	351	Missense	distal	-7	no	13.094	13.091	EPSD	ICGC;COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	O75533	SF3B1	P24941	CDK2	T362	A364D	364	Missense	proximal	2	no	15.139	15.111	EPSD	ICGC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	O75533	SF3B1	P24941	CDK2	T362	T369I	369	Missense	distal	7	no	15.139	15.500	EPSD	ICGC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	O75533	SF3B1	P24941	CDK2	T369	H374Q	374	Missense	distal	5	no	11.508	11.390	EPSD	ICGC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	O75533	SF3B1	P24941	CDK2	T369	A364D	364	Missense	distal	-5	no	11.508	11.541	EPSD	ICGC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	O75533	SF3B1	P24941	CDK2	T369	T369I	369	Missense	central	0	yes	11.508	0.000	EPSD	ICGC	8.148	Loss
CMGC_CDK_CDK2_CDK2_ST	O75533	SF3B1	P24941	CDK2	T371	H374Q	374	Missense	distal	3	no	15.690	14.643	EPSD	ICGC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	O75533	SF3B1	P24941	CDK2	T371	A364D	364	Missense	distal	-7	no	15.690	15.767	EPSD	ICGC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	O75533	SF3B1	P24941	CDK2	T371	T369I	369	Missense	proximal	-2	no	15.690	15.569	EPSD	ICGC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	O75533	SF3B1	P24941	CDK2	T379	H374Q	374	Missense	distal	-5	no	15.663	15.617	EPSD	ICGC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	O75533	SF3B1	P24941	CDK2	T426	P427Q	427	Missense	proximal	1	no	17.069	9.157	EPSD;PhosphoSitePlus	ICGC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	O75533	SF3B1	P24941	CDK2	T434	P427Q	427	Missense	distal	-7	no	12.552	12.509	EPSD	ICGC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	O75533	SF3B1	P24941	CDK2	T434	G439C	439	Missense	distal	5	no	12.552	12.659	EPSD	ICGC;COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	O75533	SF3B1	P24941	CDK2	T436	G439C	439	Missense	distal	3	no	14.000	9.455	EPSD	ICGC;COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	O75533	SF3B1	P24941	CDK2	S488	Q492K	492	Missense	distal	4	no	14.281	14.621	EPSD	ICGC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	O75533	SF3B1	P24941	CDK2	S488	E490A	490	Missense	proximal	2	no	14.281	14.209	EPSD	ICGC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	O75533	SF3B1	P24941	CDK2	T508	P510Q	510	Missense	proximal	2	no	13.239	13.298	EPSD	ICGC;COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	O75533	SF3B1	P24941	CDK2	S541	Q534P	534	Missense	distal	-7	no	13.379	13.422	EPSD	ICGC;COSMIC;CCLE	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	O75533	SF3B1	P24941	CDK2	S611	M609I	609	Missense	proximal	-2	no	7.036	8.966	EPSD	ICGC;COSMIC	8.148	Gain
CMGC_CDK_CDK2_CDK2_ST	O75533	SF3B1	P24941	CDK2	T1021	K1025N	1025	Missense	distal	4	no	14.030	13.608	EPSD	ICGC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	O75533	SF3B1	P24941	CDK2	T1170	Y1167H	1167	Missense	distal	-3	no	12.782	12.814	EPSD	ICGC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	P12272	PTHLH	P24941	CDK2	S85	P86L	86	Missense	proximal	1	no	14.581	4.760	EPSD	ICGC	8.148	Loss
CMGC_CDK_CDK2_CDK2_ST	P12272	PTHLH	P24941	CDK2	S85	N81Y	81	Missense	distal	-4	no	14.581	14.908	EPSD	ICGC;COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	P12272	PTHLH	P24941	CDK2	S85	T88K	88	Missense	distal	3	no	14.581	17.402	EPSD	ICGC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	P12272	PTHLH	P24941	CDK2	S85	N90S	90	Missense	distal	5	no	14.581	14.377	EPSD	ICGC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	P12272	PTHLH	P24941	CDK2	S85	N87S	87	Missense	proximal	2	no	14.581	14.718	EPSD	ICGC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	P12272	PTHLH	P24941	CDK2	T121	T121K	121	Missense	central	0	yes	16.482	0.000	PhosphoSitePlus	ICGC;COSMIC	8.148	Loss
CMGC_CDK_CDK2_CDK2_ST	P12272	PTHLH	P24941	CDK2	T121	P118T	118	Missense	distal	-3	no	16.482	16.442	PhosphoSitePlus	ICGC;COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	Q99741	CDC6	P24941	CDK2	S45	V39F	39	Missense	distal	-6	no	15.739	15.742	EPSD	ICGC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	Q99741	CDC6	P24941	CDK2	S45	P46L	46	Missense	proximal	1	no	15.739	5.918	EPSD	ICGC	8.148	Loss
CMGC_CDK_CDK2_CDK2_ST	Q99741	CDC6	P24941	CDK2	T67	L64V	64	Missense	distal	-3	no	11.591	11.805	EPSD	ICGC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	Q99741	CDC6	P24941	CDK2	S74	K80N	80	Missense	distal	6	no	17.009	17.004	EPSD;PhosphoSitePlus	ICGC;COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	Q99741	CDC6	P24941	CDK2	S88	H89R	89	Missense	proximal	1	no	8.365	5.325	EPSD	ICGC	8.148	Loss
CMGC_CDK_CDK2_CDK2_ST	Q99741	CDC6	P24941	CDK2	S415	L414P	414	Missense	proximal	-1	no	8.578	8.758	EPSD	ICGC;COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	Q99741	CDC6	P24941	CDK2	S415	Q408H	408	Missense	distal	-7	no	8.578	8.744	EPSD	ICGC;GDSC;CCLE	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	Q99741	CDC6	P24941	CDK2	S419	L414P	414	Missense	distal	-5	no	14.406	14.394	EPSD	ICGC;COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	P10644	PRKAR1A	P24941	CDK2	S83	P89S	89	Missense	distal	6	no	13.867	13.869	PhosphoSitePlus	ICGC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	P10644	PRKAR1A	P24941	CDK2	T209	A213S	213	Missense	distal	4	no	13.976	13.950	EPSD	ICGC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	P10644	PRKAR1A	P24941	CDK2	T209	V215F	215	Missense	distal	6	no	13.976	13.960	EPSD	ICGC;COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	Q15003	NCAPH	P24941	CDK2	S81	S81I	81	Missense	central	0	yes	13.361	0.000	EPSD	ICGC;COSMIC	8.148	Loss
CMGC_CDK_CDK2_CDK2_ST	Q15003	NCAPH	P24941	CDK2	S87	S81I	81	Missense	distal	-6	no	13.645	13.649	EPSD	ICGC;COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	Q15003	NCAPH	P24941	CDK2	S432	E427D	427	Missense	distal	-5	no	14.715	14.735	EPSD	ICGC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	Q15003	NCAPH	P24941	CDK2	S432	R434L	434	Missense	proximal	2	no	14.715	14.449	EPSD	ICGC;COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	Q15003	NCAPH	P24941	CDK2	S659	A665T	665	Missense	distal	6	no	9.039	9.051	EPSD	ICGC;COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	Q92698	RAD54L	P24941	CDK2	T31	R35L	35	Missense	distal	4	no	16.646	16.879	EPSD;PhosphoSitePlus	ICGC;COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	Q92698	RAD54L	P24941	CDK2	T31	P27H	27	Missense	distal	-4	no	16.646	16.043	EPSD;PhosphoSitePlus	ICGC;COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	Q92698	RAD54L	P24941	CDK2	S49	Q42R	42	Missense	distal	-7	no	16.250	16.637	PhosphoSitePlus;EPSD	ICGC;COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	Q92698	RAD54L	P24941	CDK2	S49	C46F	46	Missense	distal	-3	no	16.250	16.334	PhosphoSitePlus;EPSD	ICGC;COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	Q92698	RAD54L	P24941	CDK2	S49	P50S	50	Missense	proximal	1	no	16.250	4.984	PhosphoSitePlus;EPSD	ICGC	8.148	Loss
CMGC_CDK_CDK2_CDK2_ST	P30304	CDC25A	P24941	CDK2	S18	P25T	25	Missense	distal	7	no	14.800	14.496	EPSD	ICGC;COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	P30304	CDC25A	P24941	CDK2	S88	S88F	88	Missense	central	0	yes	14.456	0.000	EPSD	ICGC;COSMIC	8.148	Loss
CMGC_CDK_CDK2_CDK2_ST	P30304	CDC25A	P24941	CDK2	S88	D93E	93	Missense	distal	5	no	14.456	14.361	EPSD	ICGC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	P30304	CDC25A	P24941	CDK2	S116	P117Q	117	Missense	proximal	1	no	13.761	5.850	EPSD	ICGC	8.148	Loss
CMGC_CDK_CDK2_CDK2_ST	P30304	CDC25A	P24941	CDK2	S261	R255Q	255	Missense	distal	-6	no	12.875	12.876	EPSD	ICGC;COSMIC;GDSC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	P30304	CDC25A	P24941	CDK2	S261	N254K	254	Missense	distal	-7	no	12.875	12.909	EPSD	ICGC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	P30304	CDC25A	P24941	CDK2	S261	S263F	263	Missense	proximal	2	no	12.875	13.059	EPSD	ICGC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	P30304	CDC25A	P24941	CDK2	S279	P285H	285	Missense	distal	6	no	8.255	8.251	EPSD	ICGC;COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	P30304	CDC25A	P24941	CDK2	S283	P285H	285	Missense	proximal	2	no	15.804	15.881	PhosphoSitePlus	ICGC;COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	P30304	CDC25A	P24941	CDK2	S298	T303A	303	Missense	distal	5	no	13.338	13.373	EPSD	ICGC;COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	P30304	CDC25A	P24941	CDK2	S320	A319E	319	Missense	proximal	-1	no	7.357	8.412	EPSD	ICGC;COSMIC	8.148	Gain
CMGC_CDK_CDK2_CDK2_ST	P30304	CDC25A	P24941	CDK2	S321	S317Y	317	Missense	distal	-4	no	13.607	13.718	EPSD	ICGC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	P30304	CDC25A	P24941	CDK2	S321	S315Y	315	Missense	distal	-6	no	13.607	13.608	EPSD	ICGC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	P30304	CDC25A	P24941	CDK2	S321	A319E	319	Missense	proximal	-2	no	13.607	12.476	EPSD	ICGC;COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	P30304	CDC25A	P24941	CDK2	S321	G324R	324	Missense	distal	3	no	13.607	15.427	EPSD	ICGC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	P33981	TTK	P24941	CDK2	S49	V52F	52	Missense	distal	3	no	8.301	7.652	EPSD	ICGC;COSMIC	8.148	Loss
CMGC_CDK_CDK2_CDK2_ST	P33981	TTK	P24941	CDK2	S49	S49A	49	Missense	central	0	yes	8.301	0.000	EPSD	ICGC;COSMIC	8.148	Loss
CMGC_CDK_CDK2_CDK2_ST	P33981	TTK	P24941	CDK2	S80	D81Y	81	Missense	proximal	1	no	8.990	1.735	EPSD	ICGC	8.148	Loss
CMGC_CDK_CDK2_CDK2_ST	P33981	TTK	P24941	CDK2	S80	N75S	75	Missense	distal	-5	no	8.990	8.926	EPSD	ICGC;COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	P33981	TTK	P24941	CDK2	S80	S76G	76	Missense	distal	-4	no	8.990	8.317	EPSD	ICGC;COSMIC;GDSC;CCLE	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	P33981	TTK	P24941	CDK2	S281	D283N	283	Missense	proximal	2	no	8.574	8.506	EPSD	ICGC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	P33981	TTK	P24941	CDK2	S333	K328N	328	Missense	distal	-5	no	12.107	12.123	EPSD	ICGC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	P33981	TTK	P24941	CDK2	S837	G838S	838	Missense	proximal	1	no	8.906	4.953	EPSD	ICGC;COSMIC	8.148	Loss
CMGC_CDK_CDK2_CDK2_ST	Q15813	TBCE	P24941	CDK2	S495	S495I	495	Missense	central	0	yes	16.954	0.000	PhosphoSitePlus	ICGC	8.148	Loss
CMGC_CDK_CDK2_CDK2_ST	Q53GL7	PARP10	P24941	CDK2	S128	A127V	127	Missense	proximal	-1	no	12.307	12.534	EPSD	ICGC;COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	Q53ET0	CRTC2	P24941	CDK2	S86	A82T	82	Missense	distal	-4	no	14.848	15.074	EPSD	ICGC;COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	Q53ET0	CRTC2	P24941	CDK2	S116	P117T	117	Missense	proximal	1	no	14.667	4.710	EPSD	ICGC;COSMIC	8.148	Loss
CMGC_CDK_CDK2_CDK2_ST	Q53ET0	CRTC2	P24941	CDK2	S116	R119H	119	Missense	distal	3	no	14.667	13.970	EPSD	ICGC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	Q53ET0	CRTC2	P24941	CDK2	S128	H124Q	124	Missense	distal	-4	no	15.585	15.970	EPSD	ICGC;COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	Q53ET0	CRTC2	P24941	CDK2	S128	I125V	125	Missense	distal	-3	no	15.585	15.708	EPSD	ICGC;COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	Q53ET0	CRTC2	P24941	CDK2	S128	Y134N	134	Missense	distal	6	no	15.585	15.596	EPSD	ICGC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	Q53ET0	CRTC2	P24941	CDK2	S131	H124Q	124	Missense	distal	-7	no	13.335	13.169	EPSD	ICGC;COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	Q53ET0	CRTC2	P24941	CDK2	S131	I125V	125	Missense	distal	-6	no	13.335	13.334	EPSD	ICGC;COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	Q53ET0	CRTC2	P24941	CDK2	S131	Y134N	134	Missense	distal	3	no	13.335	13.517	EPSD	ICGC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	Q53ET0	CRTC2	P24941	CDK2	S136	Y134N	134	Missense	proximal	-2	no	14.361	13.582	EPSD	ICGC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	Q53ET0	CRTC2	P24941	CDK2	S183	Q185E	185	Missense	proximal	2	no	12.820	12.858	EPSD	ICGC;COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	Q53ET0	CRTC2	P24941	CDK2	S183	G190V	190	Missense	distal	7	no	12.820	12.409	EPSD	ICGC;COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	Q53ET0	CRTC2	P24941	CDK2	S183	S183G	183	Missense	central	0	yes	12.820	0.000	EPSD	ICGC;COSMIC	8.148	Loss
CMGC_CDK_CDK2_CDK2_ST	Q53ET0	CRTC2	P24941	CDK2	S183	S178R	178	Missense	distal	-5	no	12.820	12.912	EPSD	ICGC;COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	Q53ET0	CRTC2	P24941	CDK2	T192	Q185E	185	Missense	distal	-7	no	12.888	13.021	EPSD	ICGC;COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	Q53ET0	CRTC2	P24941	CDK2	T192	G190V	190	Missense	proximal	-2	no	12.888	12.981	EPSD	ICGC;COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	Q53ET0	CRTC2	P24941	CDK2	S336	L334I	334	Missense	proximal	-2	no	12.451	12.521	EPSD	ICGC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	Q53ET0	CRTC2	P24941	CDK2	S336	Y329C	329	Missense	distal	-7	no	12.451	12.596	EPSD	ICGC;COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	Q53ET0	CRTC2	P24941	CDK2	S408	A413T	413	Missense	distal	5	no	12.976	12.940	EPSD	ICGC;COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	Q53ET0	CRTC2	P24941	CDK2	S408	T406N	406	Missense	proximal	-2	no	12.976	11.666	EPSD	ICGC;COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	Q53ET0	CRTC2	P24941	CDK2	T420	A413T	413	Missense	distal	-7	no	13.202	13.035	EPSD	ICGC;COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	Q53ET0	CRTC2	P24941	CDK2	T420	A423G	423	Missense	distal	3	no	13.202	13.613	EPSD	ICGC;COSMIC;GDSC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	Q53ET0	CRTC2	P24941	CDK2	T420	H427N	427	Missense	distal	7	no	13.202	12.977	EPSD	ICGC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	Q53ET0	CRTC2	P24941	CDK2	T420	H426Q	426	Missense	distal	6	no	13.202	13.213	EPSD	ICGC;COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	Q53ET0	CRTC2	P24941	CDK2	S424	A423G	423	Missense	proximal	-1	no	14.789	16.108	EPSD	ICGC;COSMIC;GDSC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	Q53ET0	CRTC2	P24941	CDK2	S424	H427N	427	Missense	distal	3	no	14.789	13.205	EPSD	ICGC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	Q53ET0	CRTC2	P24941	CDK2	S424	H426Q	426	Missense	proximal	2	no	14.789	14.771	EPSD	ICGC;COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	Q53ET0	CRTC2	P24941	CDK2	S433	S436G	436	Missense	distal	3	no	13.266	13.131	PhosphoSitePlus	ICGC;COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	Q53ET0	CRTC2	P24941	CDK2	S433	A439V	439	Missense	distal	6	no	13.266	13.268	PhosphoSitePlus	ICGC;COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	Q53ET0	CRTC2	P24941	CDK2	S433	H427N	427	Missense	distal	-6	no	13.266	13.262	PhosphoSitePlus	ICGC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	Q53ET0	CRTC2	P24941	CDK2	S433	H426Q	426	Missense	distal	-7	no	13.266	13.100	PhosphoSitePlus	ICGC;COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	Q53ET0	CRTC2	P24941	CDK2	S456	F455V	455	Missense	proximal	-1	no	12.882	12.053	EPSD	ICGC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	Q53ET0	CRTC2	P24941	CDK2	S456	P457Q	457	Missense	proximal	1	no	12.882	4.971	EPSD	ICGC	8.148	Loss
CMGC_CDK_CDK2_CDK2_ST	Q53ET0	CRTC2	P24941	CDK2	S456	P452H	452	Missense	distal	-4	no	12.882	12.279	EPSD	ICGC;COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	Q53ET0	CRTC2	P24941	CDK2	S460	I466T	466	Missense	distal	6	no	14.450	14.458	EPSD	ICGC;COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	Q53ET0	CRTC2	P24941	CDK2	S460	F455V	455	Missense	distal	-5	no	14.450	14.409	EPSD	ICGC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	Q53ET0	CRTC2	P24941	CDK2	S460	P457Q	457	Missense	distal	-3	no	14.450	14.508	EPSD	ICGC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	Q53ET0	CRTC2	P24941	CDK2	S490	P487T	487	Missense	distal	-3	no	12.845	12.805	EPSD	ICGC;COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	Q53ET0	CRTC2	P24941	CDK2	T501	P499L	499	Missense	proximal	-2	no	14.544	14.320	EPSD	ICGC;COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	Q53ET0	CRTC2	P24941	CDK2	T501	P499T	499	Missense	proximal	-2	no	14.544	14.510	EPSD	ICGC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	Q53ET0	CRTC2	P24941	CDK2	T501	P508L	508	Missense	distal	7	no	14.544	14.574	EPSD	ICGC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	Q53ET0	CRTC2	P24941	CDK2	S624	G621W	621	Missense	distal	-3	no	13.549	13.716	EPSD	ICGC;COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	Q53ET0	CRTC2	P24941	CDK2	S624	D622E	622	Missense	proximal	-2	no	13.549	12.569	EPSD	ICGC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	Q53ET0	CRTC2	P24941	CDK2	S624	G626C	626	Missense	proximal	2	no	13.549	13.578	EPSD	ICGC;COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	O15350	TP73	P24941	CDK2	S8	A6T	6	Missense	proximal	-2	no	13.666	13.616	EPSD	ICGC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	O15350	TP73	P24941	CDK2	T86	A91T	91	Missense	distal	5	no	17.190	17.154	PhosphoSitePlus	ICGC;COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	O15350	TP73	P24941	CDK2	S145	P146Q	146	Missense	proximal	1	no	14.672	6.760	EPSD	ICGC;COSMIC	8.148	Loss
CMGC_CDK_CDK2_CDK2_ST	O15350	TP73	P24941	CDK2	S145	S145C	145	Missense	central	0	yes	14.672	0.000	EPSD	ICGC;COSMIC	8.148	Loss
CMGC_CDK_CDK2_CDK2_ST	O15350	TP73	P24941	CDK2	S145	T143M	143	Missense	proximal	-2	no	14.672	12.621	EPSD	ICGC;GDSC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	O15350	TP73	P24941	CDK2	T167	P168L	168	Missense	proximal	1	no	13.388	3.567	EPSD	ICGC;COSMIC	8.148	Loss
CMGC_CDK_CDK2_CDK2_ST	O15350	TP73	P24941	CDK2	T167	P160S	160	Missense	distal	-7	no	13.388	13.208	EPSD	ICGC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	O15350	TP73	P24941	CDK2	S333	V337I	337	Missense	distal	4	no	11.658	11.403	EPSD	ICGC;COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	O15350	TP73	P24941	CDK2	S333	K331N	331	Missense	proximal	-2	no	11.658	10.829	EPSD	ICGC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	O15350	TP73	P24941	CDK2	S333	A336S	336	Missense	distal	3	no	11.658	12.204	EPSD	ICGC;COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	O15350	TP73	P24941	CDK2	S412	P413S	413	Missense	proximal	1	no	12.065	0.799	EPSD	ICGC;COSMIC	8.148	Loss
CMGC_CDK_CDK2_CDK2_ST	P31943	HNRNPH1	P24941	CDK2	S104	D106E	106	Missense	proximal	2	no	14.665	14.765	PhosphoSitePlus	ICGC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	P31943	HNRNPH1	P24941	CDK2	S269	M271I	271	Missense	proximal	2	no	9.029	8.795	EPSD	ICGC;COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	P31943	HNRNPH1	P24941	CDK2	S272	M271I	271	Missense	proximal	-1	no	8.746	7.680	EPSD	ICGC;COSMIC	8.148	Loss
CMGC_CDK_CDK2_CDK2_ST	P31943	HNRNPH1	P24941	CDK2	S272	G277W	277	Missense	distal	5	no	8.746	8.893	EPSD	ICGC;COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	P31943	HNRNPH1	P24941	CDK2	S310	P311L	311	Missense	proximal	1	no	14.525	4.704	EPSD	ICGC;COSMIC	8.148	Loss
CMGC_CDK_CDK2_CDK2_ST	P31943	HNRNPH1	P24941	CDK2	S310	Y306D	306	Missense	distal	-4	no	14.525	14.586	EPSD	ICGC;COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	Q99708	RBBP8	P24941	CDK2	S10	S10I	10	Missense	central	0	yes	13.152	0.000	EPSD	ICGC;COSMIC	8.148	Loss
CMGC_CDK_CDK2_CDK2_ST	Q99708	RBBP8	P24941	CDK2	S10	A14S	14	Missense	distal	4	no	13.152	13.126	EPSD	ICGC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	Q99708	RBBP8	P24941	CDK2	S10	S6N	6	Missense	distal	-4	no	13.152	12.936	EPSD	ICGC;COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	Q99708	RBBP8	P24941	CDK2	S163	P164L	164	Missense	proximal	1	no	15.192	5.371	EPSD	ICGC;COSMIC	8.148	Loss
CMGC_CDK_CDK2_CDK2_ST	Q99708	RBBP8	P24941	CDK2	S163	A167S	167	Missense	distal	4	no	15.192	15.165	EPSD	ICGC;COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	Q99708	RBBP8	P24941	CDK2	S163	P161S	161	Missense	proximal	-2	no	15.192	14.540	EPSD	ICGC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	Q99708	RBBP8	P24941	CDK2	S163	P164Q	164	Missense	proximal	1	no	15.192	7.280	EPSD	ICGC;COSMIC	8.148	Loss
CMGC_CDK_CDK2_CDK2_ST	Q99708	RBBP8	P24941	CDK2	S163	V159I	159	Missense	distal	-4	no	15.192	15.089	EPSD	ICGC;COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	Q99708	RBBP8	P24941	CDK2	S233	D226E	226	Missense	distal	-7	no	13.121	12.970	EPSD	ICGC;COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	Q99708	RBBP8	P24941	CDK2	S233	T227I	227	Missense	distal	-6	no	13.121	13.124	EPSD	ICGC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	Q99708	RBBP8	P24941	CDK2	S233	M235I	235	Missense	proximal	2	no	13.121	12.887	EPSD	ICGC;COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	Q99708	RBBP8	P24941	CDK2	S233	S231I	231	Missense	proximal	-2	no	13.121	13.618	EPSD	ICGC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	Q99708	RBBP8	P24941	CDK2	T245	S243I	243	Missense	proximal	-2	no	13.967	14.464	EPSD	ICGC;COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	Q99708	RBBP8	P24941	CDK2	T315	E319D	319	Missense	distal	4	no	15.012	14.930	PhosphoSitePlus;EPSD	ICGC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	Q99708	RBBP8	P24941	CDK2	T315	T315P	315	Missense	central	0	yes	15.012	0.000	PhosphoSitePlus;EPSD	ICGC	8.148	Loss
CMGC_CDK_CDK2_CDK2_ST	Q99708	RBBP8	P24941	CDK2	S454	R447W	447	Missense	distal	-7	no	8.116	8.287	EPSD	ICGC	8.148	Gain
CMGC_CDK_CDK2_CDK2_ST	Q99708	RBBP8	P24941	CDK2	S454	T450S	450	Missense	distal	-4	no	8.116	8.305	EPSD	ICGC;COSMIC	8.148	Gain
CMGC_CDK_CDK2_CDK2_ST	Q99708	RBBP8	P24941	CDK2	S549	S555A	555	Missense	distal	6	no	14.273	14.267	EPSD	ICGC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	Q99708	RBBP8	P24941	CDK2	S549	P550S	550	Missense	proximal	1	no	14.273	3.007	EPSD	ICGC	8.148	Loss
CMGC_CDK_CDK2_CDK2_ST	Q99708	RBBP8	P24941	CDK2	S549	K547E	547	Missense	proximal	-2	no	14.273	13.672	EPSD	ICGC;COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	Q99708	RBBP8	P24941	CDK2	S549	G551W	551	Missense	proximal	2	no	14.273	14.411	EPSD	ICGC;COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	Q99708	RBBP8	P24941	CDK2	S679	K682Q	682	Missense	distal	3	no	10.646	7.914	EPSD	ICGC;COSMIC	8.148	Loss
CMGC_CDK_CDK2_CDK2_ST	Q99708	RBBP8	P24941	CDK2	S679	D674Y	674	Missense	distal	-5	no	10.646	10.613	EPSD	ICGC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	Q99708	RBBP8	P24941	CDK2	S679	G678D	678	Missense	proximal	-1	no	10.646	10.353	EPSD	ICGC;COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	Q99708	RBBP8	P24941	CDK2	S889	S889C	889	Missense	central	0	yes	17.646	0.000	EPSD	ICGC;COSMIC	8.148	Loss
CMGC_CDK_CDK2_CDK2_ST	Q99708	RBBP8	P24941	CDK2	S889	I887V	887	Missense	proximal	-2	no	17.646	17.151	EPSD	ICGC;COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	Q99708	RBBP8	P24941	CDK2	S889	Q882H	882	Missense	distal	-7	no	17.646	17.812	EPSD	ICGC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	Q99708	RBBP8	P24941	CDK2	S889	G892C	892	Missense	distal	3	no	17.646	13.101	EPSD	ICGC;COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	Q99708	RBBP8	P24941	CDK2	S889	S889Y	889	Missense	central	0	yes	17.646	0.000	EPSD	ICGC;COSMIC	8.148	Loss
CMGC_CDK_CDK2_CDK2_ST	Q9NYB0	TERF2IP	P24941	CDK2	S36	P37T	37	Missense	proximal	1	no	16.320	6.363	EPSD	ICGC;COSMIC	8.148	Loss
CMGC_CDK_CDK2_CDK2_ST	Q9NYB0	TERF2IP	P24941	CDK2	S111	A104P	104	Missense	distal	-7	no	9.365	9.200	EPSD	ICGC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	Q9NYB0	TERF2IP	P24941	CDK2	S154	G160C	160	Missense	distal	6	no	14.288	14.286	EPSD	ICGC;COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	Q9NYB0	TERF2IP	P24941	CDK2	S203	V202L	202	Missense	proximal	-1	no	14.838	14.702	PhosphoSitePlus	ICGC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	Q9NYB0	TERF2IP	P24941	CDK2	S203	S205F	205	Missense	proximal	2	no	14.838	15.023	PhosphoSitePlus	ICGC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	Q9NYB0	TERF2IP	P24941	CDK2	S203	Q207K	207	Missense	distal	4	no	14.838	15.179	PhosphoSitePlus	ICGC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	Q9NYB0	TERF2IP	P24941	CDK2	S269	E274G	274	Missense	distal	5	no	14.028	14.075	EPSD	ICGC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	Q9NYB0	TERF2IP	P24941	CDK2	S269	V265L	265	Missense	distal	-4	no	14.028	14.017	EPSD	ICGC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	Q9NYB0	TERF2IP	P24941	CDK2	S269	P271S	271	Missense	proximal	2	no	14.028	14.094	EPSD	ICGC;COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	Q9NYB0	TERF2IP	P24941	CDK2	S269	E274K	274	Missense	distal	5	no	14.028	13.894	EPSD	ICGC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	A1KXE4	FAM168B	P24941	CDK2	S6	G11W	11	Missense	distal	5	no	13.135	13.281	EPSD	ICGC;COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	A1KXE4	FAM168B	P24941	CDK2	S6	P3H	3	Missense	distal	-3	no	13.135	13.281	EPSD	ICGC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	A1KXE4	FAM168B	P24941	CDK2	S38	A45E	45	Missense	distal	7	no	13.468	13.128	EPSD	ICGC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	A1KXE4	FAM168B	P24941	CDK2	S38	S38Y	38	Missense	central	0	yes	13.468	0.000	EPSD	ICGC;COSMIC	8.148	Loss
CMGC_CDK_CDK2_CDK2_ST	A1KXE4	FAM168B	P24941	CDK2	T57	P58T	58	Missense	proximal	1	no	17.826	7.869	PhosphoSitePlus	ICGC	8.148	Loss
CMGC_CDK_CDK2_CDK2_ST	A1KXE4	FAM168B	P24941	CDK2	T57	P58H	58	Missense	proximal	1	no	17.826	11.067	PhosphoSitePlus	ICGC;GDSC;CCLE	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	A1KXE4	FAM168B	P24941	CDK2	T57	P55T	55	Missense	proximal	-2	no	17.826	17.792	PhosphoSitePlus	ICGC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	A1KXE4	FAM168B	P24941	CDK2	T57	Y59F	59	Missense	proximal	2	no	17.826	18.019	PhosphoSitePlus	ICGC;COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	A1KXE4	FAM168B	P24941	CDK2	S64	G68W	68	Missense	distal	4	no	14.588	14.228	EPSD	ICGC;COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	A1KXE4	FAM168B	P24941	CDK2	S64	P58H	58	Missense	distal	-6	no	14.588	14.591	EPSD	ICGC;GDSC;CCLE	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	A1KXE4	FAM168B	P24941	CDK2	S64	Y59F	59	Missense	distal	-5	no	14.588	14.636	EPSD	ICGC;COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	A1KXE4	FAM168B	P24941	CDK2	S76	P77L	77	Missense	proximal	1	no	12.960	3.139	EPSD	ICGC;COSMIC	8.148	Loss
CMGC_CDK_CDK2_CDK2_ST	A1KXE4	FAM168B	P24941	CDK2	S76	P79H	79	Missense	distal	3	no	12.960	13.982	EPSD	ICGC;COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	A1KXE4	FAM168B	P24941	CDK2	S166	A164T	164	Missense	proximal	-2	no	13.474	13.424	EPSD	ICGC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	A1KXE4	FAM168B	P24941	CDK2	T168	A164T	164	Missense	distal	-4	no	13.230	13.455	EPSD	ICGC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	A1KXE4	FAM168B	P24941	CDK2	T185	P192H	192	Missense	distal	7	no	14.540	14.672	EPSD	ICGC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	Q13330	MTA1	P24941	CDK2	S52	S53G	53	Missense	proximal	1	no	4.386	8.340	EPSD	ICGC;COSMIC	8.148	Gain
CMGC_CDK_CDK2_CDK2_ST	Q13330	MTA1	P24941	CDK2	S449	G442R	442	Missense	distal	-7	no	13.678	13.697	EPSD	ICGC;COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	Q13330	MTA1	P24941	CDK2	S522	A519V	519	Missense	distal	-3	no	14.560	14.762	PhosphoSitePlus	ICGC;COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	Q13330	MTA1	P24941	CDK2	T564	V571F	571	Missense	distal	7	no	17.708	18.151	EPSD	ICGC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	Q13330	MTA1	P24941	CDK2	T564	S562I	562	Missense	proximal	-2	no	17.708	18.205	EPSD	ICGC;COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	Q13330	MTA1	P24941	CDK2	T564	A566T	566	Missense	proximal	2	no	17.708	17.506	EPSD	ICGC;COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	Q13330	MTA1	P24941	CDK2	S576	R583H	583	Missense	distal	7	no	13.103	12.745	EPSD	ICGC;CCLE	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	Q13330	MTA1	P24941	CDK2	S576	G581V	581	Missense	distal	5	no	13.103	12.944	EPSD	ICGC;COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	Q13330	MTA1	P24941	CDK2	S576	V571F	571	Missense	distal	-5	no	13.103	13.145	EPSD	ICGC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	Q96E09	FAM122A	P24941	CDK2	S19	S26G	26	Missense	distal	7	no	12.120	12.942	EPSD	ICGC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	Q96E09	FAM122A	P24941	CDK2	S48	A55V	55	Missense	distal	7	no	16.531	16.405	EPSD	ICGC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	Q96E09	FAM122A	P24941	CDK2	S76	S83N	83	Missense	distal	7	no	15.061	15.120	EPSD	ICGC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	Q96E09	FAM122A	P24941	CDK2	S76	H81R	81	Missense	distal	5	no	15.061	15.089	EPSD	ICGC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	Q96E09	FAM122A	P24941	CDK2	S143	T149A	149	Missense	distal	6	no	13.945	13.933	PhosphoSitePlus	ICGC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	Q96E09	FAM122A	P24941	CDK2	S147	G151V	151	Missense	distal	4	no	15.447	15.794	EPSD	ICGC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	Q96E09	FAM122A	P24941	CDK2	S147	T149A	149	Missense	proximal	2	no	15.447	15.650	EPSD	ICGC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	Q96E09	FAM122A	P24941	CDK2	S158	G151V	151	Missense	distal	-7	no	11.724	11.419	EPSD	ICGC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	Q96E09	FAM122A	P24941	CDK2	S173	T179M	179	Missense	distal	6	no	13.644	13.617	EPSD	ICGC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	Q96E09	FAM122A	P24941	CDK2	S173	P176S	176	Missense	distal	3	no	13.644	13.678	EPSD	ICGC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	Q96E09	FAM122A	P24941	CDK2	S177	R181P	181	Missense	distal	4	no	14.333	14.454	EPSD	ICGC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	Q96E09	FAM122A	P24941	CDK2	S177	T179M	179	Missense	proximal	2	no	14.333	14.722	EPSD	ICGC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	Q96E09	FAM122A	P24941	CDK2	S177	P176S	176	Missense	proximal	-1	no	14.333	13.862	EPSD	ICGC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	Q96E09	FAM122A	P24941	CDK2	S177	F182C	182	Missense	distal	5	no	14.333	14.349	EPSD	ICGC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	Q96E09	FAM122A	P24941	CDK2	T180	R181P	181	Missense	proximal	1	no	4.591	14.390	EPSD	ICGC	8.148	Gain
CMGC_CDK_CDK2_CDK2_ST	Q96E09	FAM122A	P24941	CDK2	S189	C193F	193	Missense	distal	4	no	13.770	14.335	EPSD	ICGC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	Q96E09	FAM122A	P24941	CDK2	S189	F182C	182	Missense	distal	-7	no	13.770	13.670	EPSD	ICGC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	Q96E09	FAM122A	P24941	CDK2	S267	A272T	272	Missense	distal	5	no	16.388	16.352	EPSD	ICGC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	Q96E09	FAM122A	P24941	CDK2	S270	A272T	272	Missense	proximal	2	no	14.960	14.758	EPSD	ICGC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	Q96E09	FAM122A	P24941	CDK2	S276	A272T	272	Missense	distal	-4	no	14.278	14.503	EPSD	ICGC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	Q6P1N0	CC2D1A	P24941	CDK2	T120	P122S	122	Missense	proximal	2	no	15.093	15.160	EPSD	ICGC;COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	Q6P1N0	CC2D1A	P24941	CDK2	T120	A117S	117	Missense	distal	-3	no	15.093	15.247	EPSD	ICGC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	Q6P1N0	CC2D1A	P24941	CDK2	T204	T204M	204	Missense	central	0	yes	12.465	0.000	EPSD	ICGC;COSMIC;CCLE	8.148	Loss
CMGC_CDK_CDK2_CDK2_ST	Q6P1N0	CC2D1A	P24941	CDK2	S208	T204M	204	Missense	distal	-4	no	14.363	13.449	PhosphoSitePlus	ICGC;COSMIC;CCLE	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	Q6P1N0	CC2D1A	P24941	CDK2	S239	Q246K	246	Missense	distal	7	no	12.662	12.530	EPSD	ICGC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	Q6P1N0	CC2D1A	P24941	CDK2	S253	Q259K	259	Missense	distal	6	no	14.311	14.313	EPSD	ICGC;COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	Q6P1N0	CC2D1A	P24941	CDK2	S253	Q246K	246	Missense	distal	-7	no	14.311	14.306	EPSD	ICGC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	Q6P1N0	CC2D1A	P24941	CDK2	S324	Q317H	317	Missense	distal	-7	no	13.414	13.580	EPSD	ICGC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	Q6P1N0	CC2D1A	P24941	CDK2	S324	T331S	331	Missense	distal	7	no	13.414	13.566	EPSD	ICGC;COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	Q6P1N0	CC2D1A	P24941	CDK2	S324	S327W	327	Missense	distal	3	no	13.414	12.459	EPSD	ICGC;COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	Q6P1N0	CC2D1A	P24941	CDK2	S324	T331P	331	Missense	distal	7	no	13.414	13.718	EPSD	ICGC;CCLE	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	Q6P1N0	CC2D1A	P24941	CDK2	T331	S327W	327	Missense	distal	-4	no	13.394	12.039	EPSD	ICGC;COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	Q6P1N0	CC2D1A	P24941	CDK2	T331	T331P	331	Missense	central	0	yes	13.394	0.000	EPSD	ICGC;CCLE	8.148	Loss
CMGC_CDK_CDK2_CDK2_ST	Q6P1N0	CC2D1A	P24941	CDK2	T331	T338S	338	Missense	distal	7	no	13.394	13.546	EPSD	ICGC;COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	Q6P1N0	CC2D1A	P24941	CDK2	S455	Q453H	453	Missense	proximal	-2	no	12.604	12.161	EPSD	ICGC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	Q6P1N0	CC2D1A	P24941	CDK2	T669	P671T	671	Missense	proximal	2	no	13.449	13.272	EPSD	ICGC;COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	Q6P1N0	CC2D1A	P24941	CDK2	S674	P671T	671	Missense	distal	-3	no	9.643	9.603	EPSD	ICGC;COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	Q6P1N0	CC2D1A	P24941	CDK2	S707	K711N	711	Missense	distal	4	no	17.429	17.007	EPSD	ICGC;COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	Q6P1N0	CC2D1A	P24941	CDK2	S837	G838W	838	Missense	proximal	1	no	9.405	1.495	EPSD	ICGC;COSMIC	8.148	Loss
CMGC_CDK_CDK2_CDK2_ST	Q53H80	AKIRIN2	P24941	CDK2	S18	P15Q	15	Missense	distal	-3	no	12.101	12.159	EPSD;PhosphoSitePlus	ICGC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	Q53H80	AKIRIN2	P24941	CDK2	S21	P15Q	15	Missense	distal	-6	no	14.977	14.980	PhosphoSitePlus;EPSD	ICGC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	Q53H80	AKIRIN2	P24941	CDK2	S39	P40Q	40	Missense	proximal	1	no	12.353	4.442	EPSD	ICGC;COSMIC	8.148	Loss
CMGC_CDK_CDK2_CDK2_ST	Q53H80	AKIRIN2	P24941	CDK2	S125	A131V	131	Missense	distal	6	no	13.914	13.917	EPSD	ICGC;COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	Q53H80	AKIRIN2	P24941	CDK2	S125	G127W	127	Missense	proximal	2	no	13.914	14.052	EPSD	ICGC;COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	Q53H80	AKIRIN2	P24941	CDK2	S134	E139K	139	Missense	distal	5	no	18.141	18.008	EPSD	ICGC;COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	Q53H80	AKIRIN2	P24941	CDK2	S134	P141T	141	Missense	distal	7	no	18.141	17.837	EPSD	ICGC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	Q53H80	AKIRIN2	P24941	CDK2	S134	A131V	131	Missense	distal	-3	no	18.141	18.342	EPSD	ICGC;COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	Q53H80	AKIRIN2	P24941	CDK2	S134	G127W	127	Missense	distal	-7	no	18.141	18.331	EPSD	ICGC;COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	P54198	HIRA	P24941	CDK2	S437	L438P	438	Missense	proximal	1	no	3.452	13.273	EPSD	ICGC;COSMIC	8.148	Gain
CMGC_CDK_CDK2_CDK2_ST	P54198	HIRA	P24941	CDK2	T508	S515L	515	Missense	distal	7	no	11.841	12.024	EPSD	ICGC;COSMIC;GDSC;CCLE	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	P54198	HIRA	P24941	CDK2	T508	L501I	501	Missense	distal	-7	no	11.841	12.030	EPSD	ICGC;COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	P54198	HIRA	P24941	CDK2	T508	P503Q	503	Missense	distal	-5	no	11.841	11.842	EPSD	ICGC;COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	P54198	HIRA	P24941	CDK2	T544	D537E	537	Missense	distal	-7	no	12.375	12.224	EPSD	ICGC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	P54198	HIRA	P24941	CDK2	T544	M539I	539	Missense	distal	-5	no	12.375	12.307	EPSD	ICGC;COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	P54198	HIRA	P24941	CDK2	T544	P545H	545	Missense	proximal	1	no	12.375	5.617	EPSD	ICGC	8.148	Loss
CMGC_CDK_CDK2_CDK2_ST	P54198	HIRA	P24941	CDK2	S549	P556Q	556	Missense	distal	7	no	16.587	16.432	EPSD	ICGC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	P54198	HIRA	P24941	CDK2	S549	P545H	545	Missense	distal	-4	no	16.587	15.983	EPSD	ICGC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	P54198	HIRA	P24941	CDK2	T555	P556Q	556	Missense	proximal	1	no	17.342	9.431	PhosphoSitePlus	ICGC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	P54198	HIRA	P24941	CDK2	T555	E560K	560	Missense	distal	5	no	17.342	17.209	PhosphoSitePlus	ICGC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	P54198	HIRA	P24941	CDK2	T586	E591K	591	Missense	distal	5	no	15.477	15.344	EPSD	ICGC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	P54198	HIRA	P24941	CDK2	S614	D613E	613	Missense	proximal	-1	no	8.248	8.278	EPSD	ICGC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	P54198	HIRA	P24941	CDK2	S661	P654H	654	Missense	distal	-7	no	12.205	12.328	EPSD	ICGC;COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	P54198	HIRA	P24941	CDK2	S687	R690K	690	Missense	distal	3	no	18.403	19.392	EPSD	ICGC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	P54198	HIRA	P24941	CDK2	S769	R765S	765	Missense	distal	-4	no	11.894	12.491	EPSD	ICGC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	P54198	HIRA	P24941	CDK2	S769	L772F	772	Missense	distal	3	no	11.894	12.236	EPSD	ICGC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	P54198	HIRA	P24941	CDK2	S775	L772F	772	Missense	distal	-3	no	14.723	14.980	EPSD	ICGC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	Q01167	FOXK2	P24941	CDK2	S30	V37M	37	Missense	distal	7	no	15.524	15.811	EPSD	ICGC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	Q01167	FOXK2	P24941	CDK2	S195	S195N	195	Missense	central	0	yes	14.585	0.000	EPSD	ICGC;COSMIC	8.148	Loss
CMGC_CDK_CDK2_CDK2_ST	Q01167	FOXK2	P24941	CDK2	S199	S195N	195	Missense	distal	-4	no	13.080	12.864	EPSD	ICGC;COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	Q01167	FOXK2	P24941	CDK2	S199	A206T	206	Missense	distal	7	no	13.080	12.391	EPSD	ICGC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	Q01167	FOXK2	P24941	CDK2	S213	A206T	206	Missense	distal	-7	no	14.683	14.516	EPSD	ICGC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	Q01167	FOXK2	P24941	CDK2	S252	P253Q	253	Missense	proximal	1	no	14.392	6.481	EPSD	ICGC;COSMIC	8.148	Loss
CMGC_CDK_CDK2_CDK2_ST	Q01167	FOXK2	P24941	CDK2	T360	L362V	362	Missense	proximal	2	no	9.430	9.659	EPSD	ICGC;COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	Q01167	FOXK2	P24941	CDK2	T360	V355M	355	Missense	distal	-5	no	9.430	9.505	EPSD	ICGC;GDSC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	Q01167	FOXK2	P24941	CDK2	T360	L362M	362	Missense	proximal	2	no	9.430	9.747	EPSD	ICGC;COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	Q01167	FOXK2	P24941	CDK2	T360	R353S	353	Missense	distal	-7	no	9.430	8.906	EPSD	ICGC;COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	Q01167	FOXK2	P24941	CDK2	S373	A377T	377	Missense	distal	4	no	14.662	14.905	PhosphoSitePlus;EPSD	ICGC;COSMIC;GDSC;CCLE	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	Q01167	FOXK2	P24941	CDK2	S373	P374H	374	Missense	proximal	1	no	14.662	7.904	PhosphoSitePlus;EPSD	ICGC;COSMIC	8.148	Loss
CMGC_CDK_CDK2_CDK2_ST	Q01167	FOXK2	P24941	CDK2	T389	Q388K	388	Missense	proximal	-1	no	12.721	12.928	EPSD	ICGC;COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	Q01167	FOXK2	P24941	CDK2	S398	P399L	399	Missense	proximal	1	no	15.587	5.766	EPSD	ICGC;COSMIC	8.148	Loss
CMGC_CDK_CDK2_CDK2_ST	Q01167	FOXK2	P24941	CDK2	S398	P404L	404	Missense	distal	6	no	15.587	15.588	EPSD	ICGC;COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	Q01167	FOXK2	P24941	CDK2	S428	P426S	426	Missense	proximal	-2	no	14.799	14.148	EPSD;PhosphoSitePlus	ICGC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	Q01167	FOXK2	P24941	CDK2	T552	I559T	559	Missense	distal	7	no	12.870	12.509	EPSD	ICGC;COSMIC;GDSC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	Q01167	FOXK2	P24941	CDK2	S599	A605S	605	Missense	distal	6	no	15.293	15.299	EPSD	ICGC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	Q01167	FOXK2	P24941	CDK2	T648	V641F	641	Missense	distal	-7	no	15.161	15.513	EPSD	ICGC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	Q01167	FOXK2	P24941	CDK2	T648	L644M	644	Missense	distal	-4	no	15.161	14.471	EPSD	ICGC;COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	P30307	CDC25C	P24941	CDK2	T48	G55S	55	Missense	distal	7	no	13.569	12.747	EPSD	ICGC;COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	P30307	CDC25C	P24941	CDK2	T67	R70C	70	Missense	distal	3	no	15.210	8.846	EPSD	ICGC;COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	P30307	CDC25C	P24941	CDK2	T130	R136H	136	Missense	distal	6	no	10.654	10.665	EPSD	ICGC;COSMIC;GDSC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	P30307	CDC25C	P24941	CDK2	T130	R136S	136	Missense	distal	6	no	10.654	10.671	EPSD	ICGC;COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	P30307	CDC25C	P24941	CDK2	S168	T172A	172	Missense	distal	4	no	16.715	16.472	EPSD	ICGC;COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	P30307	CDC25C	P24941	CDK2	S214	E219D	219	Missense	distal	5	no	13.103	13.198	PhosphoSitePlus	ICGC;COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	Q9Y2K7	KDM2A	P24941	CDK2	S180	E183D	183	Missense	distal	3	no	8.580	6.145	EPSD	ICGC;COSMIC	8.148	Loss
CMGC_CDK_CDK2_CDK2_ST	Q9Y2K7	KDM2A	P24941	CDK2	S394	A397T	397	Missense	distal	3	no	14.691	15.089	EPSD	ICGC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	Q9Y2K7	KDM2A	P24941	CDK2	T550	A557T	557	Missense	distal	7	no	14.987	14.298	PhosphoSitePlus	ICGC;COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	Q9Y2K7	KDM2A	P24941	CDK2	S558	A557T	557	Missense	proximal	-1	no	15.036	15.043	EPSD	ICGC;COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	Q9Y2K7	KDM2A	P24941	CDK2	S558	V561M	561	Missense	distal	3	no	15.036	14.187	EPSD	ICGC;COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	Q9Y2K7	KDM2A	P24941	CDK2	S562	A557T	557	Missense	distal	-5	no	8.245	8.219	EPSD	ICGC;COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	Q9Y2K7	KDM2A	P24941	CDK2	S562	V561M	561	Missense	proximal	-1	no	8.245	9.338	EPSD	ICGC;COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	Q9Y2K7	KDM2A	P24941	CDK2	T713	R706W	706	Missense	distal	-7	no	15.120	15.290	EPSD	ICGC;COSMIC;GDSC;CCLE	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	Q9Y2K7	KDM2A	P24941	CDK2	T713	D709Y	709	Missense	distal	-4	no	15.120	15.058	EPSD	ICGC;COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	Q9Y2K7	KDM2A	P24941	CDK2	S731	R733Q	733	Missense	proximal	2	no	12.131	12.032	EPSD	ICGC;COSMIC;GDSC;CCLE	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	Q9Y2K7	KDM2A	P24941	CDK2	S731	R738L	738	Missense	distal	7	no	12.131	11.672	EPSD	ICGC;COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	Q9Y2K7	KDM2A	P24941	CDK2	S740	R733Q	733	Missense	distal	-7	no	13.188	12.801	EPSD	ICGC;COSMIC;GDSC;CCLE	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	Q9Y2K7	KDM2A	P24941	CDK2	S740	G744V	744	Missense	distal	4	no	13.188	13.534	EPSD	ICGC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	Q9Y2K7	KDM2A	P24941	CDK2	S740	R738L	738	Missense	proximal	-2	no	13.188	14.199	EPSD	ICGC;COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	Q9Y2K7	KDM2A	P24941	CDK2	S781	E777K	777	Missense	distal	-4	no	8.153	7.842	EPSD	ICGC;COSMIC	8.148	Loss
CMGC_CDK_CDK2_CDK2_ST	Q9Y2K7	KDM2A	P24941	CDK2	S781	E788G	788	Missense	distal	7	no	8.153	8.779	EPSD	ICGC;COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	Q9Y2K7	KDM2A	P24941	CDK2	S781	P780L	780	Missense	proximal	-1	no	8.153	7.974	EPSD	ICGC;COSMIC	8.148	Loss
CMGC_CDK_CDK2_CDK2_ST	Q14207	NPAT	P24941	CDK2	S102	A106D	106	Missense	distal	4	no	12.263	12.159	EPSD	ICGC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	Q14207	NPAT	P24941	CDK2	S102	A106T	106	Missense	distal	4	no	12.263	12.506	EPSD	ICGC;COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	Q14207	NPAT	P24941	CDK2	T149	T148S	148	Missense	proximal	-1	no	11.660	11.452	EPSD	ICGC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	Q14207	NPAT	P24941	CDK2	S207	M206L	206	Missense	proximal	-1	no	16.393	15.164	EPSD	ICGC;COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	Q14207	NPAT	P24941	CDK2	S207	R211H	211	Missense	distal	4	no	16.393	16.276	EPSD	ICGC;COSMIC;GDSC;CCLE	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	Q14207	NPAT	P24941	CDK2	S535	L540F	540	Missense	distal	5	no	8.532	8.709	EPSD	ICGC;COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	Q14207	NPAT	P24941	CDK2	S535	S535F	535	Missense	central	0	yes	8.532	0.000	EPSD	ICGC;COSMIC	8.148	Loss
CMGC_CDK_CDK2_CDK2_ST	Q14207	NPAT	P24941	CDK2	T688	E683K	683	Missense	distal	-5	no	13.285	13.250	EPSD	ICGC;COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	Q14207	NPAT	P24941	CDK2	T688	P690Q	690	Missense	proximal	2	no	13.285	13.344	EPSD	ICGC;COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	Q14207	NPAT	P24941	CDK2	T693	P690Q	690	Missense	distal	-3	no	13.038	13.096	EPSD	ICGC;COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	Q14207	NPAT	P24941	CDK2	S700	L701P	701	Missense	proximal	1	no	4.302	14.123	EPSD	ICGC;COSMIC	8.148	Gain
CMGC_CDK_CDK2_CDK2_ST	Q14207	NPAT	P24941	CDK2	S775	P769S	769	Missense	distal	-6	no	13.624	13.623	EPSD;PhosphoSitePlus	ICGC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	Q14207	NPAT	P24941	CDK2	T908	R911K	911	Missense	distal	3	no	12.485	13.474	EPSD	ICGC;COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	Q14207	NPAT	P24941	CDK2	T1270	T1270K	1270	Missense	central	0	yes	16.167	0.000	EPSD;PhosphoSitePlus	ICGC;COSMIC	8.148	Loss
CMGC_CDK_CDK2_CDK2_ST	Q01196	RUNX1	P24941	CDK2	S21	M25V	25	Missense	distal	4	no	16.779	17.427	EPSD	ICGC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	P49450	CENPA	P24941	CDK2	S37	S36F	36	Missense	proximal	-1	no	7.892	9.149	EPSD	ICGC	8.148	Gain
CMGC_CDK_CDK2_CDK2_ST	P48200	IREB2	P24941	CDK2	S157	Q151R	151	Missense	distal	-6	no	18.378	18.377	PhosphoSitePlus	ICGC;COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	P48200	IREB2	P24941	CDK2	S157	K155Q	155	Missense	proximal	-2	no	18.378	18.325	PhosphoSitePlus	ICGC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	P48200	IREB2	P24941	CDK2	S157	V159L	159	Missense	proximal	2	no	18.378	18.148	PhosphoSitePlus	ICGC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	P48200	IREB2	P24941	CDK2	T777	R779L	779	Missense	proximal	2	no	14.247	13.981	EPSD	ICGC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	P48200	IREB2	P24941	CDK2	T777	P778L	778	Missense	proximal	1	no	14.247	4.426	EPSD	ICGC	8.148	Loss
CMGC_CDK_CDK2_CDK2_ST	P30050	RPL12	P24941	CDK2	S38	G33A	33	Missense	distal	-5	no	18.470	18.415	PhosphoSitePlus	ICGC;COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	Q9NYF8	BCLAF1	P24941	CDK2	S44	R51S	51	Missense	distal	7	no	8.178	7.536	EPSD	ICGC	8.148	Loss
CMGC_CDK_CDK2_CDK2_ST	Q9NYF8	BCLAF1	P24941	CDK2	S104	R109H	109	Missense	distal	5	no	16.166	16.138	EPSD	ICGC;COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	Q9NYF8	BCLAF1	P24941	CDK2	S114	S112Y	112	Missense	proximal	-2	no	14.129	14.216	EPSD	ICGC;COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	Q9NYF8	BCLAF1	P24941	CDK2	S127	R128H	128	Missense	proximal	1	no	5.481	8.521	EPSD	ICGC;COSMIC	8.148	Gain
CMGC_CDK_CDK2_CDK2_ST	Q9NYF8	BCLAF1	P24941	CDK2	S138	S135Y	135	Missense	distal	-3	no	16.318	16.338	EPSD	ICGC;COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	Q9NYF8	BCLAF1	P24941	CDK2	S138	S142A	142	Missense	distal	4	no	16.318	16.345	EPSD	ICGC;COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	Q9NYF8	BCLAF1	P24941	CDK2	S148	S146T	146	Missense	proximal	-2	no	14.186	14.804	EPSD	ICGC;COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	Q9NYF8	BCLAF1	P24941	CDK2	S148	S146Y	146	Missense	proximal	-2	no	14.186	14.273	EPSD	ICGC;COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	Q9NYF8	BCLAF1	P24941	CDK2	S148	S148F	148	Missense	central	0	yes	14.186	0.000	EPSD	ICGC	8.148	Loss
CMGC_CDK_CDK2_CDK2_ST	Q9NYF8	BCLAF1	P24941	CDK2	S148	S146F	146	Missense	proximal	-2	no	14.186	13.725	EPSD	ICGC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	Q9NYF8	BCLAF1	P24941	CDK2	S153	S146T	146	Missense	distal	-7	no	12.146	12.323	EPSD	ICGC;COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	Q9NYF8	BCLAF1	P24941	CDK2	S153	S146Y	146	Missense	distal	-7	no	12.146	12.452	EPSD	ICGC;COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	Q9NYF8	BCLAF1	P24941	CDK2	S153	S148F	148	Missense	distal	-5	no	12.146	12.262	EPSD	ICGC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	Q9NYF8	BCLAF1	P24941	CDK2	S153	S146F	146	Missense	distal	-7	no	12.146	12.697	EPSD	ICGC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	Q9NYF8	BCLAF1	P24941	CDK2	S222	P223R	223	Missense	proximal	1	no	14.360	4.562	EPSD	ICGC;COSMIC	8.148	Loss
CMGC_CDK_CDK2_CDK2_ST	Q9NYF8	BCLAF1	P24941	CDK2	S222	D220Y	220	Missense	proximal	-2	no	14.360	13.931	EPSD	ICGC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	Q9NYF8	BCLAF1	P24941	CDK2	S225	P223R	223	Missense	proximal	-2	no	14.937	13.701	EPSD	ICGC;COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	Q9NYF8	BCLAF1	P24941	CDK2	S225	D220Y	220	Missense	distal	-5	no	14.937	14.904	EPSD	ICGC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	Q9NYF8	BCLAF1	P24941	CDK2	S228	P235Q	235	Missense	distal	7	no	12.823	12.668	EPSD	ICGC;COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	Q9NYF8	BCLAF1	P24941	CDK2	S228	P223R	223	Missense	distal	-5	no	12.823	12.870	EPSD	ICGC;COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	Q9NYF8	BCLAF1	P24941	CDK2	S230	P235Q	235	Missense	distal	5	no	11.833	11.793	EPSD	ICGC;COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	Q9NYF8	BCLAF1	P24941	CDK2	S230	P223R	223	Missense	distal	-7	no	11.833	12.177	EPSD	ICGC;COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	Q9NYF8	BCLAF1	P24941	CDK2	T234	P235Q	235	Missense	proximal	1	no	13.445	5.533	EPSD	ICGC;COSMIC	8.148	Loss
CMGC_CDK_CDK2_CDK2_ST	Q9NYF8	BCLAF1	P24941	CDK2	T234	Q238K	238	Missense	distal	4	no	13.445	13.785	EPSD	ICGC;COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	Q9NYF8	BCLAF1	P24941	CDK2	T234	S241Y	241	Missense	distal	7	no	13.445	13.866	EPSD	ICGC;COSMIC;GDSC;CCLE	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	Q9NYF8	BCLAF1	P24941	CDK2	T257	S262F	262	Missense	distal	5	no	11.189	11.507	EPSD	ICGC;COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	Q9NYF8	BCLAF1	P24941	CDK2	S268	S272F	272	Missense	distal	4	no	15.574	15.378	EPSD	ICGC;COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	Q9NYF8	BCLAF1	P24941	CDK2	S268	S262F	262	Missense	distal	-6	no	15.574	15.579	EPSD	ICGC;COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	Q9NYF8	BCLAF1	P24941	CDK2	S285	S281Y	281	Missense	distal	-4	no	14.602	14.713	EPSD	ICGC;COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	Q9NYF8	BCLAF1	P24941	CDK2	S285	G278R	278	Missense	distal	-7	no	14.602	14.621	EPSD	ICGC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	Q9NYF8	BCLAF1	P24941	CDK2	S290	S297L	297	Missense	distal	7	no	13.271	13.453	EPSD	ICGC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	Q9NYF8	BCLAF1	P24941	CDK2	S290	H293Y	293	Missense	distal	3	no	13.271	11.503	EPSD	ICGC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	Q9NYF8	BCLAF1	P24941	CDK2	S300	S297L	297	Missense	distal	-3	no	17.632	17.466	EPSD	ICGC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	Q9NYF8	BCLAF1	P24941	CDK2	S300	H293Y	293	Missense	distal	-7	no	17.632	17.635	EPSD	ICGC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	Q9NYF8	BCLAF1	P24941	CDK2	S385	K391M	391	Missense	distal	6	no	8.344	8.317	EPSD	ICGC;COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	Q9NYF8	BCLAF1	P24941	CDK2	S389	K391M	391	Missense	proximal	2	no	9.361	9.713	EPSD	ICGC;COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	Q9NYF8	BCLAF1	P24941	CDK2	S542	S540F	540	Missense	proximal	-2	no	8.937	8.475	EPSD	ICGC;COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	Q9NYF8	BCLAF1	P24941	CDK2	S542	S540Y	540	Missense	proximal	-2	no	8.937	9.024	EPSD	ICGC;COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	Q9NYF8	BCLAF1	P24941	CDK2	S757	S757F	757	Missense	central	0	yes	14.470	0.000	EPSD	ICGC;COSMIC	8.148	Loss
CMGC_CDK_CDK2_CDK2_ST	Q9NYF8	BCLAF1	P24941	CDK2	S757	S752F	752	Missense	distal	-5	no	14.470	14.587	EPSD	ICGC;COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	Q9NYF8	BCLAF1	P24941	CDK2	S760	S757F	757	Missense	distal	-3	no	13.962	14.053	EPSD	ICGC;COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	Q9UM11	FZR1	P24941	CDK2	T30	L31P	31	Missense	proximal	1	no	4.524	14.345	EPSD	ICGC	8.148	Gain
CMGC_CDK_CDK2_CDK2_ST	Q9UM11	FZR1	P24941	CDK2	T32	L31P	31	Missense	proximal	-1	no	14.341	14.521	EPSD	ICGC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	Q9UM11	FZR1	P24941	CDK2	T32	P37T	37	Missense	distal	5	no	14.341	14.316	EPSD	ICGC;COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	Q9UM11	FZR1	P24941	CDK2	T32	P33H	33	Missense	proximal	1	no	14.341	7.583	EPSD	ICGC;COSMIC	8.148	Loss
CMGC_CDK_CDK2_CDK2_ST	Q9UM11	FZR1	P24941	CDK2	S36	L31P	31	Missense	distal	-5	no	13.707	13.695	EPSD	ICGC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	Q9UM11	FZR1	P24941	CDK2	S36	P37T	37	Missense	proximal	1	no	13.707	3.749	EPSD	ICGC;COSMIC	8.148	Loss
CMGC_CDK_CDK2_CDK2_ST	Q9UM11	FZR1	P24941	CDK2	S36	P33H	33	Missense	distal	-3	no	13.707	13.853	EPSD	ICGC;COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	Q9UM11	FZR1	P24941	CDK2	S40	R47C	47	Missense	distal	7	no	15.649	15.801	PhosphoSitePlus;EPSD	ICGC;COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	Q9UM11	FZR1	P24941	CDK2	S40	P37T	37	Missense	distal	-3	no	15.649	15.610	PhosphoSitePlus;EPSD	ICGC;COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	Q9UM11	FZR1	P24941	CDK2	S40	P33H	33	Missense	distal	-7	no	15.649	15.773	PhosphoSitePlus;EPSD	ICGC;COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	Q9UM11	FZR1	P24941	CDK2	T121	L117V	117	Missense	distal	-4	no	18.297	18.307	EPSD;PhosphoSitePlus	ICGC;COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	Q9UM11	FZR1	P24941	CDK2	T121	K125E	125	Missense	distal	4	no	18.297	17.912	EPSD;PhosphoSitePlus	ICGC;COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	Q9UM11	FZR1	P24941	CDK2	S138	R136L	136	Missense	proximal	-2	no	8.586	9.598	EPSD	ICGC;COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	Q9UM11	FZR1	P24941	CDK2	S138	K135T	135	Missense	distal	-3	no	8.586	8.587	EPSD	ICGC;COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	Q9UM11	FZR1	P24941	CDK2	S163	P164L	164	Missense	proximal	1	no	17.211	7.390	EPSD;PhosphoSitePlus	ICGC	8.148	Loss
CMGC_CDK_CDK2_CDK2_ST	Q9UM11	FZR1	P24941	CDK2	S346	S343P	343	Missense	distal	-3	no	11.717	11.622	EPSD	ICGC;COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	P49459	UBE2A	P24941	CDK2	S120	A127V	127	Missense	distal	7	no	17.215	17.089	PhosphoSitePlus	ICGC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	P49459	UBE2A	P24941	CDK2	S124	A127V	127	Missense	distal	3	no	7.649	8.770	EPSD	ICGC	8.148	Gain
CMGC_CDK_CDK2_CDK2_ST	Q08050	FOXM1	P24941	CDK2	S4	R6C	6	Missense	proximal	2	no	12.345	12.332	EPSD	ICGC;COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	Q08050	FOXM1	P24941	CDK2	S35	S41C	41	Missense	distal	6	no	14.560	14.545	EPSD	ICGC;COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	Q08050	FOXM1	P24941	CDK2	S331	P335T	335	Missense	distal	4	no	15.331	15.613	EPSD	ICGC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	Q08050	FOXM1	P24941	CDK2	S331	P335S	335	Missense	distal	4	no	15.331	15.344	EPSD	ICGC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	Q08050	FOXM1	P24941	CDK2	S340	P335T	335	Missense	distal	-5	no	11.158	11.156	EPSD	ICGC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	Q08050	FOXM1	P24941	CDK2	S340	P345Q	345	Missense	distal	5	no	11.158	11.117	EPSD	ICGC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	Q08050	FOXM1	P24941	CDK2	S340	P335S	335	Missense	distal	-5	no	11.158	11.113	EPSD	ICGC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	Q08050	FOXM1	P24941	CDK2	S508	P509T	509	Missense	proximal	1	no	13.254	3.297	EPSD	ICGC;COSMIC	8.148	Loss
CMGC_CDK_CDK2_CDK2_ST	Q08050	FOXM1	P24941	CDK2	T510	P509T	509	Missense	proximal	-1	no	17.092	16.829	EPSD	ICGC;COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	Q08050	FOXM1	P24941	CDK2	T627	G634R	634	Missense	distal	7	no	13.034	12.853	EPSD	ICGC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	Q08050	FOXM1	P24941	CDK2	S638	G634R	634	Missense	distal	-4	no	15.660	15.735	EPSD	ICGC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	Q9Y2W1	THRAP3	P24941	CDK2	S134	P130S	130	Missense	distal	-4	no	12.306	12.661	EPSD	ICGC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	Q9Y2W1	THRAP3	P24941	CDK2	S136	H142R	142	Missense	distal	6	no	11.087	11.076	EPSD	ICGC;COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	Q9Y2W1	THRAP3	P24941	CDK2	S136	P130S	130	Missense	distal	-6	no	11.087	11.086	EPSD	ICGC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	Q9Y2W1	THRAP3	P24941	CDK2	S243	R245L	245	Missense	proximal	2	no	15.395	15.130	EPSD	ICGC;COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	Q9Y2W1	THRAP3	P24941	CDK2	S243	P249A	249	Missense	distal	6	no	15.395	15.391	EPSD	ICGC;COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	Q9Y2W1	THRAP3	P24941	CDK2	S243	R245Q	245	Missense	proximal	2	no	15.395	15.296	EPSD	ICGC;COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	Q9Y2W1	THRAP3	P24941	CDK2	S248	R245L	245	Missense	distal	-3	no	10.981	10.721	EPSD	ICGC;COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	Q9Y2W1	THRAP3	P24941	CDK2	S248	P249A	249	Missense	proximal	1	no	10.981	-3.423	EPSD	ICGC;COSMIC	8.148	Loss
CMGC_CDK_CDK2_CDK2_ST	Q9Y2W1	THRAP3	P24941	CDK2	S248	R245Q	245	Missense	distal	-3	no	10.981	10.850	EPSD	ICGC;COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	Q9Y2W1	THRAP3	P24941	CDK2	S253	P249A	249	Missense	distal	-4	no	14.178	14.119	EPSD	ICGC;COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	Q9Y2W1	THRAP3	P24941	CDK2	S264	V270M	270	Missense	distal	6	no	10.417	10.399	EPSD	ICGC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	Q9Y2W1	THRAP3	P24941	CDK2	S268	V270M	270	Missense	proximal	2	no	12.706	12.794	EPSD	ICGC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	Q9Y2W1	THRAP3	P24941	CDK2	S268	P273H	273	Missense	distal	5	no	12.706	12.784	EPSD	ICGC;COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	Q9Y2W1	THRAP3	P24941	CDK2	S274	V270M	270	Missense	distal	-4	no	12.230	11.530	EPSD	ICGC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	Q9Y2W1	THRAP3	P24941	CDK2	S274	P276L	276	Missense	proximal	2	no	12.230	12.123	EPSD	ICGC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	Q9Y2W1	THRAP3	P24941	CDK2	S274	P273H	273	Missense	proximal	-1	no	12.230	12.349	EPSD	ICGC;COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	Q9Y2W1	THRAP3	P24941	CDK2	S310	P316T	316	Missense	distal	6	no	16.360	16.367	EPSD	ICGC;COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	Q9Y2W1	THRAP3	P24941	CDK2	S310	P311Q	311	Missense	proximal	1	no	16.360	8.448	EPSD	ICGC;COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	Q9Y2W1	THRAP3	P24941	CDK2	S315	P316T	316	Missense	proximal	1	no	11.071	1.113	EPSD	ICGC;COSMIC	8.148	Loss
CMGC_CDK_CDK2_CDK2_ST	Q9Y2W1	THRAP3	P24941	CDK2	S315	P311Q	311	Missense	distal	-4	no	11.071	10.852	EPSD	ICGC;COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	Q9Y2W1	THRAP3	P24941	CDK2	S320	P316T	316	Missense	distal	-4	no	12.934	13.101	EPSD	ICGC;COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	Q9Y2W1	THRAP3	P24941	CDK2	T367	K363E	363	Missense	distal	-4	no	8.127	8.438	EPSD	ICGC;COSMIC	8.148	Gain
CMGC_CDK_CDK2_CDK2_ST	Q9Y2W1	THRAP3	P24941	CDK2	S408	Y412H	412	Missense	distal	4	no	14.974	14.537	EPSD	ICGC;COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	Q9Y2W1	THRAP3	P24941	CDK2	S408	R404L	404	Missense	distal	-4	no	14.974	15.159	EPSD	ICGC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	Q9Y2W1	THRAP3	P24941	CDK2	S408	P402S	402	Missense	distal	-6	no	14.974	14.973	EPSD	ICGC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	Q9Y2W1	THRAP3	P24941	CDK2	S616	A617P	617	Missense	proximal	1	no	0.057	14.460	EPSD	ICGC;COSMIC	8.148	Gain
CMGC_CDK_CDK2_CDK2_ST	Q9Y2W1	THRAP3	P24941	CDK2	S622	R621C	621	Missense	proximal	-1	no	16.415	15.717	EPSD	ICGC;COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	Q9Y2W1	THRAP3	P24941	CDK2	S622	A617P	617	Missense	distal	-5	no	16.415	16.390	EPSD	ICGC;COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	Q9Y2W1	THRAP3	P24941	CDK2	S672	I675T	675	Missense	distal	3	no	11.734	12.288	EPSD	ICGC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	Q9Y2W1	THRAP3	P24941	CDK2	S682	I675T	675	Missense	distal	-7	no	13.357	13.160	EPSD	ICGC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	Q9Y2W1	THRAP3	P24941	CDK2	S682	S682F	682	Missense	central	0	yes	13.357	0.000	EPSD	ICGC;COSMIC	8.148	Loss
CMGC_CDK_CDK2_CDK2_ST	Q9Y2W1	THRAP3	P24941	CDK2	S698	R700Q	700	Missense	proximal	2	no	12.761	12.661	EPSD	ICGC;COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	Q9Y2W1	THRAP3	P24941	CDK2	S698	S698R	698	Missense	central	0	yes	12.761	0.000	EPSD	ICGC;COSMIC	8.148	Loss
CMGC_CDK_CDK2_CDK2_ST	Q9Y2W1	THRAP3	P24941	CDK2	T799	A792S	792	Missense	distal	-7	no	8.478	8.134	EPSD	ICGC	8.148	Loss
CMGC_CDK_CDK2_CDK2_ST	Q9Y2W1	THRAP3	P24941	CDK2	T799	E804D	804	Missense	distal	5	no	8.478	8.573	EPSD	ICGC;COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	Q9Y2W1	THRAP3	P24941	CDK2	S849	N852K	852	Missense	distal	3	no	5.624	8.895	EPSD	ICGC;COSMIC	8.148	Gain
CMGC_CDK_CDK2_CDK2_ST	Q9Y2W1	THRAP3	P24941	CDK2	T874	Y880C	880	Missense	distal	6	no	13.970	13.964	PhosphoSitePlus	ICGC;COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	Q9Y2W1	THRAP3	P24941	CDK2	S919	R914L	914	Missense	distal	-5	no	13.602	13.567	EPSD	ICGC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	Q9Y2W1	THRAP3	P24941	CDK2	S919	P920H	920	Missense	proximal	1	no	13.602	6.843	EPSD	ICGC;COSMIC	8.148	Loss
CMGC_CDK_CDK2_CDK2_ST	Q9Y2W1	THRAP3	P24941	CDK2	S939	G940E	940	Missense	proximal	1	no	9.791	7.938	EPSD	ICGC	8.148	Loss
CMGC_CDK_CDK2_CDK2_ST	Q9Y2W1	THRAP3	P24941	CDK2	S939	E938K	938	Missense	proximal	-1	no	9.791	8.906	EPSD	ICGC;COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	Q9Y2W1	THRAP3	P24941	CDK2	S939	E942D	942	Missense	distal	3	no	9.791	7.355	EPSD	ICGC	8.148	Loss
CMGC_CDK_CDK2_CDK2_ST	Q9Y2W1	THRAP3	P24941	CDK2	S939	D937N	937	Missense	proximal	-2	no	9.791	8.583	EPSD	ICGC;COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	Q9Y2W1	THRAP3	P24941	CDK2	T941	G940E	940	Missense	proximal	-1	no	10.445	10.182	EPSD	ICGC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	Q9Y2W1	THRAP3	P24941	CDK2	T941	E938K	938	Missense	distal	-3	no	10.445	10.230	EPSD	ICGC;COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	Q9Y2W1	THRAP3	P24941	CDK2	T941	E942D	942	Missense	proximal	1	no	10.445	11.367	EPSD	ICGC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	Q9Y2W1	THRAP3	P24941	CDK2	T941	D937N	937	Missense	distal	-4	no	10.445	10.057	EPSD	ICGC;COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	Q9H425	C1orf198	P24941	CDK2	S17	A10D	10	Missense	distal	-7	no	9.478	9.554	EPSD	ICGC;COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	Q9H425	C1orf198	P24941	CDK2	T211	L210I	210	Missense	proximal	-1	no	14.429	14.591	EPSD	ICGC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	Q9H425	C1orf198	P24941	CDK2	S272	S273G	273	Missense	proximal	1	no	5.070	9.023	EPSD	ICGC;COSMIC	8.148	Gain
CMGC_CDK_CDK2_CDK2_ST	P15927	RPA2	P24941	CDK2	S23	A17E	17	Missense	distal	-6	no	12.634	12.637	EPSD;PhosphoSitePlus	ICGC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	P49736	MCM2	P24941	CDK2	S13	R18P	18	Missense	distal	5	no	13.598	13.491	EPSD;PhosphoSitePlus	ICGC;GDSC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	P49736	MCM2	P24941	CDK2	S13	A11S	11	Missense	proximal	-2	no	13.598	12.930	EPSD;PhosphoSitePlus	ICGC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	P49736	MCM2	P24941	CDK2	S27	R33Q	33	Missense	distal	6	no	15.798	15.820	EPSD;PhosphoSitePlus	ICGC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	P49736	MCM2	P24941	CDK2	T39	S40P	40	Missense	proximal	1	no	2.507	13.773	EPSD	ICGC;COSMIC	8.148	Gain
CMGC_CDK_CDK2_CDK2_ST	P49736	MCM2	P24941	CDK2	S41	S40P	40	Missense	proximal	-1	no	15.832	16.303	PhosphoSitePlus;EPSD	ICGC;COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	P49736	MCM2	P24941	CDK2	S53	G58V	58	Missense	distal	5	no	8.480	8.320	EPSD;PhosphoSitePlus	ICGC;COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	P49736	MCM2	P24941	CDK2	S53	D51Y	51	Missense	proximal	-2	no	8.480	8.050	EPSD;PhosphoSitePlus	ICGC;COSMIC	8.148	Loss
CMGC_CDK_CDK2_CDK2_ST	P49736	MCM2	P24941	CDK2	S53	S53F	53	Missense	central	0	yes	8.480	0.000	EPSD;PhosphoSitePlus	ICGC	8.148	Loss
CMGC_CDK_CDK2_CDK2_ST	P49736	MCM2	P24941	CDK2	S108	A107S	107	Missense	proximal	-1	no	9.985	9.784	EPSD;PhosphoSitePlus	ICGC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	P49736	MCM2	P24941	CDK2	S108	R115Q	115	Missense	distal	7	no	9.985	9.340	EPSD;PhosphoSitePlus	ICGC;COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	P49736	MCM2	P24941	CDK2	S139	E145D	145	Missense	distal	6	no	8.904	8.892	EPSD;PhosphoSitePlus	ICGC;COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	P49736	MCM2	P24941	CDK2	S139	R132C	132	Missense	distal	-7	no	8.904	8.831	EPSD;PhosphoSitePlus	ICGC;COSMIC;CCLE	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	P49736	MCM2	P24941	CDK2	S209	N213S	213	Missense	distal	4	no	9.821	9.854	EPSD	ICGC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	P49736	MCM2	P24941	CDK2	S209	N213Y	213	Missense	distal	4	no	9.821	10.040	EPSD	ICGC;COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	P49736	MCM2	P24941	CDK2	S209	V214F	214	Missense	distal	5	no	9.821	10.072	EPSD	ICGC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	P49736	MCM2	P24941	CDK2	S209	R204L	204	Missense	distal	-5	no	9.821	9.786	EPSD	ICGC;COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	P49736	MCM2	P24941	CDK2	S381	R375C	375	Missense	distal	-6	no	17.631	17.634	EPSD	ICGC;COSMIC;GDSC;CCLE	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	P49736	MCM2	P24941	CDK2	S381	A386V	386	Missense	distal	5	no	17.631	17.588	EPSD	ICGC;COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	P49736	MCM2	P24941	CDK2	S381	R377Q	377	Missense	distal	-4	no	17.631	17.656	EPSD	ICGC;COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	P49736	MCM2	P24941	CDK2	T805	V810A	810	Missense	distal	5	no	9.534	9.577	EPSD	ICGC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	P55273	CDKN2D	P24941	CDK2	S66	S73F	73	Missense	distal	7	no	14.025	14.879	EPSD	ICGC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	P55273	CDKN2D	P24941	CDK2	S76	V78F	78	Missense	proximal	2	no	15.359	15.488	PhosphoSitePlus	ICGC;COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	P55273	CDKN2D	P24941	CDK2	S76	S73F	73	Missense	distal	-3	no	15.359	15.451	PhosphoSitePlus	ICGC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	Q14191	WRN	P24941	CDK2	S179	W175C	175	Missense	distal	-4	no	8.451	8.700	EPSD	ICGC;COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	Q14191	WRN	P24941	CDK2	S179	T174I	174	Missense	distal	-5	no	8.451	8.492	EPSD	ICGC;COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	Q14191	WRN	P24941	CDK2	S453	D460N	460	Missense	distal	7	no	14.048	13.268	EPSD	ICGC;COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	Q14191	WRN	P24941	CDK2	S453	D460Y	460	Missense	distal	7	no	14.048	13.631	EPSD	ICGC;COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	Q14191	WRN	P24941	CDK2	S453	N459I	459	Missense	distal	6	no	14.048	14.044	EPSD	ICGC;COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	Q14191	WRN	P24941	CDK2	T490	S492Y	492	Missense	proximal	2	no	9.946	9.938	EPSD	ICGC;COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	Q14191	WRN	P24941	CDK2	S547	S548I	548	Missense	proximal	1	no	9.595	6.740	EPSD	ICGC;COSMIC	8.148	Loss
CMGC_CDK_CDK2_CDK2_ST	Q14191	WRN	P24941	CDK2	S547	Q553H	553	Missense	distal	6	no	9.595	9.584	EPSD	ICGC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	Q14191	WRN	P24941	CDK2	T629	I631N	631	Missense	proximal	2	no	8.331	8.284	EPSD	ICGC;COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	Q14191	WRN	P24941	CDK2	T629	L628V	628	Missense	proximal	-1	no	8.331	8.467	EPSD	ICGC;COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	Q14191	WRN	P24941	CDK2	T629	I631M	631	Missense	proximal	2	no	8.331	8.565	EPSD	ICGC;COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	Q14191	WRN	P24941	CDK2	T777	L784P	784	Missense	distal	7	no	9.156	9.125	EPSD	ICGC;COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	Q14191	WRN	P24941	CDK2	S1133	V1131L	1131	Missense	proximal	-2	no	16.492	16.917	PhosphoSitePlus	ICGC;COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	Q7Z2Z1	TICRR	P24941	CDK2	S120	R127Q	127	Missense	distal	7	no	18.017	17.373	EPSD	ICGC;COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	Q7Z2Z1	TICRR	P24941	CDK2	S120	P124T	124	Missense	distal	4	no	18.017	18.300	EPSD	ICGC;COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	Q7Z2Z1	TICRR	P24941	CDK2	S292	R287C	287	Missense	distal	-5	no	12.175	12.209	EPSD	ICGC;COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	Q7Z2Z1	TICRR	P24941	CDK2	S292	A297S	297	Missense	distal	5	no	12.175	12.064	EPSD	ICGC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	Q7Z2Z1	TICRR	P24941	CDK2	S441	A437V	437	Missense	distal	-4	no	13.855	13.866	EPSD	ICGC;COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	Q7Z2Z1	TICRR	P24941	CDK2	T486	G483V	483	Missense	distal	-3	no	12.195	12.234	EPSD	ICGC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	Q7Z2Z1	TICRR	P24941	CDK2	S489	T486S	486	Missense	distal	-3	no	19.263	19.398	EPSD	ICGC;COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	Q7Z2Z1	TICRR	P24941	CDK2	S489	G483V	483	Missense	distal	-6	no	19.263	19.262	EPSD	ICGC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	Q7Z2Z1	TICRR	P24941	CDK2	S489	W496L	496	Missense	distal	7	no	19.263	18.404	EPSD	ICGC;COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	Q7Z2Z1	TICRR	P24941	CDK2	T566	K571N	571	Missense	distal	5	no	16.179	16.336	EPSD	ICGC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	Q7Z2Z1	TICRR	P24941	CDK2	S599	P600L	600	Missense	proximal	1	no	15.711	5.890	EPSD	ICGC;GDSC;CCLE	8.148	Loss
CMGC_CDK_CDK2_CDK2_ST	Q7Z2Z1	TICRR	P24941	CDK2	S599	A603S	603	Missense	distal	4	no	15.711	15.685	EPSD	ICGC;COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	Q7Z2Z1	TICRR	P24941	CDK2	S599	G598D	598	Missense	proximal	-1	no	15.711	15.418	EPSD	ICGC;COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	Q7Z2Z1	TICRR	P24941	CDK2	S820	P821L	821	Missense	proximal	1	no	11.353	1.533	EPSD	ICGC	8.148	Loss
CMGC_CDK_CDK2_CDK2_ST	Q7Z2Z1	TICRR	P24941	CDK2	S923	K926N	926	Missense	distal	3	no	14.714	11.444	EPSD	ICGC;COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	Q7Z2Z1	TICRR	P24941	CDK2	S936	G932V	932	Missense	distal	-4	no	10.012	10.282	EPSD	ICGC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	Q7Z2Z1	TICRR	P24941	CDK2	S936	A941S	941	Missense	distal	5	no	10.012	9.901	EPSD	ICGC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	Q7Z2Z1	TICRR	P24941	CDK2	T969	V971L	971	Missense	proximal	2	no	17.379	17.150	EPSD;PhosphoSitePlus	ICGC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	Q7Z2Z1	TICRR	P24941	CDK2	T969	K973E	973	Missense	distal	4	no	17.379	16.994	EPSD;PhosphoSitePlus	ICGC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	Q7Z2Z1	TICRR	P24941	CDK2	S1013	L1019F	1019	Missense	distal	6	no	12.891	12.872	EPSD	ICGC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	Q7Z2Z1	TICRR	P24941	CDK2	S1033	Q1034H	1034	Missense	proximal	1	no	11.049	12.202	EPSD	ICGC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	Q7Z2Z1	TICRR	P24941	CDK2	S1078	P1079H	1079	Missense	proximal	1	no	14.068	7.309	EPSD	ICGC;COSMIC	8.148	Loss
CMGC_CDK_CDK2_CDK2_ST	Q7Z2Z1	TICRR	P24941	CDK2	T1127	P1131L	1131	Missense	distal	4	no	9.261	9.373	EPSD	ICGC;COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	Q7Z2Z1	TICRR	P24941	CDK2	T1130	P1131L	1131	Missense	proximal	1	no	15.757	5.936	EPSD	ICGC;COSMIC	8.148	Loss
CMGC_CDK_CDK2_CDK2_ST	Q7Z2Z1	TICRR	P24941	CDK2	T1134	P1131L	1131	Missense	distal	-3	no	15.645	15.574	EPSD	ICGC;COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	Q7Z2Z1	TICRR	P24941	CDK2	T1250	P1252Q	1252	Missense	proximal	2	no	14.822	14.881	EPSD	ICGC;COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	Q7Z2Z1	TICRR	P24941	CDK2	T1260	T1260M	1260	Missense	central	0	yes	12.789	0.000	EPSD	ICGC	8.148	Loss
CMGC_CDK_CDK2_CDK2_ST	Q7Z2Z1	TICRR	P24941	CDK2	T1291	K1293N	1293	Missense	proximal	2	no	15.267	15.338	EPSD	ICGC;COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	Q7Z2Z1	TICRR	P24941	CDK2	S1303	S1302Y	1302	Missense	proximal	-1	no	15.541	16.451	EPSD	ICGC;COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	Q7Z2Z1	TICRR	P24941	CDK2	T1307	S1302Y	1302	Missense	distal	-5	no	13.313	13.381	EPSD	ICGC;COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	Q7Z2Z1	TICRR	P24941	CDK2	S1323	K1321N	1321	Missense	proximal	-2	no	14.953	14.125	EPSD	ICGC;COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	Q7Z2Z1	TICRR	P24941	CDK2	S1346	V1349I	1349	Missense	distal	3	no	16.971	15.695	EPSD	ICGC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	Q7Z2Z1	TICRR	P24941	CDK2	S1346	S1348G	1348	Missense	proximal	2	no	16.971	17.022	EPSD	ICGC;COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	Q7Z2Z1	TICRR	P24941	CDK2	S1346	A1351T	1351	Missense	distal	5	no	16.971	16.935	EPSD	ICGC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	Q7Z2Z1	TICRR	P24941	CDK2	S1413	D1419N	1419	Missense	distal	6	no	13.924	13.943	EPSD	ICGC;COSMIC;GDSC;CCLE	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	Q7Z2Z1	TICRR	P24941	CDK2	S1430	P1434S	1434	Missense	distal	4	no	13.042	13.055	EPSD	ICGC;COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	Q7Z2Z1	TICRR	P24941	CDK2	S1433	R1438L	1438	Missense	distal	5	no	15.113	15.047	EPSD	ICGC;COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	Q7Z2Z1	TICRR	P24941	CDK2	S1433	P1434S	1434	Missense	proximal	1	no	15.113	3.847	EPSD	ICGC;COSMIC	8.148	Loss
CMGC_CDK_CDK2_CDK2_ST	Q7Z2Z1	TICRR	P24941	CDK2	S1453	I1457V	1457	Missense	distal	4	no	14.539	14.795	EPSD	ICGC;COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	Q7Z2Z1	TICRR	P24941	CDK2	S1509	P1510L	1510	Missense	proximal	1	no	14.053	4.232	EPSD	ICGC	8.148	Loss
CMGC_CDK_CDK2_CDK2_ST	Q7Z2Z1	TICRR	P24941	CDK2	S1517	R1523C	1523	Missense	distal	6	no	14.740	14.743	EPSD	ICGC;COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	Q7Z2Z1	TICRR	P24941	CDK2	S1517	P1510L	1510	Missense	distal	-7	no	14.740	14.746	EPSD	ICGC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	Q7Z2Z1	TICRR	P24941	CDK2	S1623	E1618D	1618	Missense	distal	-5	no	8.531	8.552	EPSD	ICGC;GDSC;CCLE	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	Q7Z2Z1	TICRR	P24941	CDK2	S1623	C1626S	1626	Missense	distal	3	no	8.531	13.211	EPSD	ICGC;GDSC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	Q7Z2Z1	TICRR	P24941	CDK2	T1633	C1626S	1626	Missense	distal	-7	no	14.610	14.159	EPSD	ICGC;GDSC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	Q7Z2Z1	TICRR	P24941	CDK2	S1806	G1805V	1805	Missense	proximal	-1	no	12.714	11.622	EPSD	ICGC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	Q7Z2Z1	TICRR	P24941	CDK2	S1806	K1801N	1801	Missense	distal	-5	no	12.714	12.730	EPSD	ICGC;COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	Q7Z2Z1	TICRR	P24941	CDK2	T1828	C1833F	1833	Missense	distal	5	no	12.561	12.545	EPSD	ICGC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	Q7Z2Z1	TICRR	P24941	CDK2	S1850	A1843V	1843	Missense	distal	-7	no	12.937	12.793	EPSD	ICGC;COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	Q7Z2Z1	TICRR	P24941	CDK2	S1881	R1885C	1885	Missense	distal	4	no	13.327	12.700	EPSD	ICGC;COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	Q7Z2Z1	TICRR	P24941	CDK2	S1881	T1877A	1877	Missense	distal	-4	no	13.327	13.102	EPSD	ICGC;COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	Q9NP87	POLM	P24941	CDK2	S12	S19Y	19	Missense	distal	7	no	13.841	14.262	EPSD	ICGC;COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	Q9NP87	POLM	P24941	CDK2	S12	R5W	5	Missense	distal	-7	no	13.841	14.011	EPSD	ICGC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	Q9NP87	POLM	P24941	CDK2	S12	D16Y	16	Missense	distal	4	no	13.841	14.105	EPSD	ICGC;CCLE	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	Q9NP87	POLM	P24941	CDK2	S12	G11R	11	Missense	proximal	-1	no	13.841	13.363	EPSD	ICGC;COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	Q9NP87	POLM	P24941	CDK2	T21	S19Y	19	Missense	proximal	-2	no	11.040	11.127	EPSD	ICGC;COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	Q9NP87	POLM	P24941	CDK2	T21	D16Y	16	Missense	distal	-5	no	11.040	11.006	EPSD	ICGC;CCLE	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	Q9NP87	POLM	P24941	CDK2	T21	T21K	21	Missense	central	0	yes	11.040	0.000	EPSD	ICGC;COSMIC	8.148	Loss
CMGC_CDK_CDK2_CDK2_ST	Q9NP87	POLM	P24941	CDK2	T95	P92L	92	Missense	distal	-3	no	12.319	12.248	EPSD	ICGC;COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	Q9NP87	POLM	P24941	CDK2	T95	C94R	94	Missense	proximal	-1	no	12.319	13.017	EPSD	ICGC;COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	P33991	MCM4	P24941	CDK2	S32	R38I	38	Missense	distal	6	no	13.864	13.880	EPSD;PhosphoSitePlus	ICGC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	P33991	MCM4	P24941	CDK2	S32	S34C	34	Missense	proximal	2	no	13.864	13.943	EPSD;PhosphoSitePlus	ICGC;COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	P33991	MCM4	P24941	CDK2	S32	R36K	36	Missense	distal	4	no	13.864	14.386	EPSD;PhosphoSitePlus	ICGC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	P33991	MCM4	P24941	CDK2	S61	A64V	64	Missense	distal	3	no	10.740	11.860	EPSD	ICGC;COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	P33991	MCM4	P24941	CDK2	S71	A64V	64	Missense	distal	-7	no	11.911	11.766	EPSD	ICGC;COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	P33991	MCM4	P24941	CDK2	S88	G93C	93	Missense	distal	5	no	11.564	11.671	EPSD	ICGC;COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	P33991	MCM4	P24941	CDK2	T94	G93C	93	Missense	proximal	-1	no	13.486	12.310	EPSD	ICGC;COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	P33991	MCM4	P24941	CDK2	T102	G106V	106	Missense	distal	4	no	13.992	14.339	EPSD	ICGC;COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	P33991	MCM4	P24941	CDK2	T102	P103Q	103	Missense	proximal	1	no	13.992	6.080	EPSD	ICGC;COSMIC	8.148	Loss
CMGC_CDK_CDK2_CDK2_ST	P33991	MCM4	P24941	CDK2	S105	G106V	106	Missense	proximal	1	no	8.680	-0.920	EPSD	ICGC;COSMIC	8.148	Loss
CMGC_CDK_CDK2_CDK2_ST	P33991	MCM4	P24941	CDK2	S105	P103Q	103	Missense	proximal	-2	no	8.680	8.113	EPSD	ICGC;COSMIC	8.148	Loss
CMGC_CDK_CDK2_CDK2_ST	P33991	MCM4	P24941	CDK2	T110	G106V	106	Missense	distal	-4	no	15.856	16.126	PhosphoSitePlus;EPSD	ICGC;COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	P33991	MCM4	P24941	CDK2	T110	R115S	115	Missense	distal	5	no	15.856	15.649	PhosphoSitePlus;EPSD	ICGC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	P33991	MCM4	P24941	CDK2	T110	Q114E	114	Missense	distal	4	no	15.856	15.812	PhosphoSitePlus;EPSD	ICGC;COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	P33991	MCM4	P24941	CDK2	T110	P103Q	103	Missense	distal	-7	no	15.856	15.813	PhosphoSitePlus;EPSD	ICGC;COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	P33991	MCM4	P24941	CDK2	S357	G364V	364	Missense	distal	7	no	12.710	12.299	EPSD	ICGC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	P06401	PGR	P24941	CDK2	S20	G17S	17	Missense	distal	-3	no	13.421	13.413	EPSD	ICGC;COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	P06401	PGR	P24941	CDK2	S20	V14M	14	Missense	distal	-6	no	13.421	13.427	EPSD	ICGC;COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	P06401	PGR	P24941	CDK2	S130	Q126K	126	Missense	distal	-4	no	12.920	13.057	EPSD	ICGC;COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	P06401	PGR	P24941	CDK2	S162	S168Y	168	Missense	distal	6	no	13.200	13.191	EPSD;PhosphoSitePlus	ICGC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	P06401	PGR	P24941	CDK2	S162	L164I	164	Missense	proximal	2	no	13.200	13.284	EPSD;PhosphoSitePlus	ICGC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	P06401	PGR	P24941	CDK2	S190	L189M	189	Missense	proximal	-1	no	14.476	15.705	EPSD;PhosphoSitePlus	ICGC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	P06401	PGR	P24941	CDK2	S190	R193Q	193	Missense	distal	3	no	14.476	12.733	EPSD;PhosphoSitePlus	ICGC;COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	P06401	PGR	P24941	CDK2	S190	K183N	183	Missense	distal	-7	no	14.476	14.442	EPSD;PhosphoSitePlus	ICGC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	P06401	PGR	P24941	CDK2	S213	A208T	208	Missense	distal	-5	no	14.599	14.573	EPSD;PhosphoSitePlus	ICGC;COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	P06401	PGR	P24941	CDK2	S294	T299M	299	Missense	distal	5	no	13.753	14.086	EPSD;PhosphoSitePlus	ICGC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	P06401	PGR	P24941	CDK2	S294	P291L	291	Missense	distal	-3	no	13.753	13.682	EPSD;PhosphoSitePlus	ICGC;COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	P06401	PGR	P24941	CDK2	S294	A287T	287	Missense	distal	-7	no	13.753	13.586	EPSD;PhosphoSitePlus	ICGC;GDSC;CCLE	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	P06401	PGR	P24941	CDK2	S345	R343W	343	Missense	proximal	-2	no	13.491	12.992	EPSD	ICGC;COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	P06401	PGR	P24941	CDK2	S345	P341L	341	Missense	distal	-4	no	13.491	13.433	EPSD	ICGC;COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	P06401	PGR	P24941	CDK2	S345	P341T	341	Missense	distal	-4	no	13.491	13.658	EPSD	ICGC;COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	P06401	PGR	P24941	CDK2	S345	P352Q	352	Missense	distal	7	no	13.491	13.337	EPSD	ICGC;COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	P06401	PGR	P24941	CDK2	T351	P352Q	352	Missense	proximal	1	no	13.300	5.389	EPSD	ICGC;COSMIC	8.148	Loss
CMGC_CDK_CDK2_CDK2_ST	P06401	PGR	P24941	CDK2	S400	S400F	400	Missense	central	0	yes	15.850	0.000	EPSD;PhosphoSitePlus	ICGC;COSMIC	8.148	Loss
CMGC_CDK_CDK2_CDK2_ST	P06401	PGR	P24941	CDK2	S554	E560D	560	Missense	distal	6	no	13.084	13.072	EPSD	ICGC;COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	P06401	PGR	P24941	CDK2	S554	P555Q	555	Missense	proximal	1	no	13.084	5.173	EPSD	ICGC;COSMIC;GDSC;CCLE	8.148	Loss
CMGC_CDK_CDK2_CDK2_ST	O00571	DDX3X	P24941	CDK2	S114	G117R	117	Missense	distal	3	no	10.774	12.593	EPSD	ICGC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	O00571	DDX3X	P24941	CDK2	T323	A322V	322	Missense	proximal	-1	no	15.023	15.250	EPSD	ICGC;COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	O00571	DDX3X	P24941	CDK2	T323	M330K	330	Missense	distal	7	no	15.023	14.192	EPSD	ICGC;COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	O00571	DDX3X	P24941	CDK2	T323	R326C	326	Missense	distal	3	no	15.023	8.659	EPSD	ICGC;COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	O00571	DDX3X	P24941	CDK2	T323	C317F	317	Missense	distal	-6	no	15.023	15.022	EPSD	ICGC;COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	O00571	DDX3X	P24941	CDK2	T323	G325R	325	Missense	proximal	2	no	15.023	15.064	EPSD	ICGC;COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	O00571	DDX3X	P24941	CDK2	T323	D329Y	329	Missense	distal	6	no	15.023	15.031	EPSD	ICGC;COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	O00571	DDX3X	P24941	CDK2	T323	D329V	329	Missense	distal	6	no	15.023	15.037	EPSD	ICGC;COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	O00571	DDX3X	P24941	CDK2	S489	F487L	487	Missense	proximal	-2	no	8.315	9.204	EPSD	ICGC;COSMIC;GDSC;CCLE	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	O00571	DDX3X	P24941	CDK2	S489	L495V	495	Missense	distal	6	no	8.315	8.312	EPSD	ICGC;COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	O00571	DDX3X	P24941	CDK2	S489	V496M	496	Missense	distal	7	no	8.315	8.601	EPSD	ICGC;COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	O00571	DDX3X	P24941	CDK2	S489	R488S	488	Missense	proximal	-1	no	8.315	7.273	EPSD	ICGC;COSMIC	8.148	Loss
CMGC_CDK_CDK2_CDK2_ST	O00571	DDX3X	P24941	CDK2	S492	F487L	487	Missense	distal	-5	no	12.554	12.493	EPSD	ICGC;COSMIC;GDSC;CCLE	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	O00571	DDX3X	P24941	CDK2	S492	L495V	495	Missense	distal	3	no	12.554	13.546	EPSD	ICGC;COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	O00571	DDX3X	P24941	CDK2	S492	V496M	496	Missense	distal	4	no	12.554	11.906	EPSD	ICGC;COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	O00571	DDX3X	P24941	CDK2	S492	R488S	488	Missense	distal	-4	no	12.554	13.151	EPSD	ICGC;COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	O00571	DDX3X	P24941	CDK2	S623	G627V	627	Missense	distal	4	no	8.786	9.133	EPSD	ICGC;COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	Q9BXR0	QTRT1	P24941	CDK2	S139	G133V	133	Missense	distal	-6	no	17.548	17.547	PhosphoSitePlus	ICGC;COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	Q9BXR0	QTRT1	P24941	CDK2	S139	P140L	140	Missense	proximal	1	no	17.548	7.727	PhosphoSitePlus	ICGC	8.148	Loss
CMGC_CDK_CDK2_CDK2_ST	Q9BXR0	QTRT1	P24941	CDK2	S246	T247P	247	Missense	proximal	1	no	6.640	16.597	EPSD	ICGC;CCLE	8.148	Gain
CMGC_CDK_CDK2_CDK2_ST	P18858	LIG1	P24941	CDK2	S91	C87Y	87	Missense	distal	-4	no	13.319	14.536	PhosphoSitePlus;EPSD	ICGC;COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	P18858	LIG1	P24941	CDK2	S91	R94H	94	Missense	distal	3	no	13.319	12.622	PhosphoSitePlus;EPSD	ICGC;COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	P18858	LIG1	P24941	CDK2	S98	R94H	94	Missense	distal	-4	no	13.237	12.876	EPSD	ICGC;COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	P18858	LIG1	P24941	CDK2	T159	T165N	165	Missense	distal	6	no	13.016	13.012	EPSD	ICGC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	P18858	LIG1	P24941	CDK2	T159	T159M	159	Missense	central	0	yes	13.016	0.000	EPSD	ICGC;COSMIC	8.148	Loss
CMGC_CDK_CDK2_CDK2_ST	P18858	LIG1	P24941	CDK2	T233	T227A	227	Missense	distal	-6	no	16.182	16.181	EPSD;PhosphoSitePlus	ICGC;COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	Q96KS0	EGLN2	P24941	CDK2	S74	R77L	77	Missense	distal	3	no	17.052	14.950	EPSD	ICGC;COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	Q96KS0	EGLN2	P24941	CDK2	S130	D127G	127	Missense	distal	-3	no	15.587	15.626	PhosphoSitePlus	ICGC;COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	Q96KS0	EGLN2	P24941	CDK2	S130	P129S	129	Missense	proximal	-1	no	15.587	15.116	PhosphoSitePlus	ICGC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	Q9H2G4	TSPYL2	P24941	CDK2	S20	R13H	13	Missense	distal	-7	no	16.178	15.958	EPSD;PhosphoSitePlus	ICGC;COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	Q9H2G4	TSPYL2	P24941	CDK2	S20	E19D	19	Missense	proximal	-1	no	16.178	16.149	EPSD;PhosphoSitePlus	ICGC;COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	Q9H2G4	TSPYL2	P24941	CDK2	S20	Q22H	22	Missense	proximal	2	no	16.178	16.197	EPSD;PhosphoSitePlus	ICGC;COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	Q9H2G4	TSPYL2	P24941	CDK2	S20	P27L	27	Missense	distal	7	no	16.178	16.209	EPSD;PhosphoSitePlus	ICGC;COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	P15923	TCF3	P24941	CDK2	S102	Y108H	108	Missense	distal	6	no	9.422	9.425	EPSD	ICGC;COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	P15923	TCF3	P24941	CDK2	S102	G103C	103	Missense	proximal	1	no	9.422	-2.195	EPSD	ICGC;COSMIC	8.148	Loss
CMGC_CDK_CDK2_CDK2_ST	P15923	TCF3	P24941	CDK2	T121	Q122H	122	Missense	proximal	1	no	7.426	8.579	EPSD	ICGC;COSMIC	8.148	Gain
CMGC_CDK_CDK2_CDK2_ST	P15923	TCF3	P24941	CDK2	S134	P140S	140	Missense	distal	6	no	13.345	13.346	EPSD	ICGC;CCLE	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	P15923	TCF3	P24941	CDK2	S134	G136W	136	Missense	proximal	2	no	13.345	13.483	EPSD	ICGC;COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	P15923	TCF3	P24941	CDK2	S139	P140S	140	Missense	proximal	1	no	13.086	1.820	EPSD;PhosphoSitePlus	ICGC;CCLE	8.148	Loss
CMGC_CDK_CDK2_CDK2_ST	P15923	TCF3	P24941	CDK2	S139	G136W	136	Missense	distal	-3	no	13.086	13.252	EPSD;PhosphoSitePlus	ICGC;COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	P15923	TCF3	P24941	CDK2	S139	K144Q	144	Missense	distal	5	no	13.086	13.100	EPSD;PhosphoSitePlus	ICGC;COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	P15923	TCF3	P24941	CDK2	T205	A212V	212	Missense	distal	7	no	14.417	14.291	EPSD	ICGC;COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	P15923	TCF3	P24941	CDK2	S229	P231Q	231	Missense	proximal	2	no	14.122	14.181	EPSD	ICGC;COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	P15923	TCF3	P24941	CDK2	S229	P231L	231	Missense	proximal	2	no	14.122	14.015	EPSD	ICGC;COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	P15923	TCF3	P24941	CDK2	S229	P231S	231	Missense	proximal	2	no	14.122	14.189	EPSD	ICGC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	P15923	TCF3	P24941	CDK2	S229	A234V	234	Missense	distal	5	no	14.122	14.079	EPSD	ICGC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	P15923	TCF3	P24941	CDK2	S245	P250L	250	Missense	distal	5	no	13.859	13.899	PhosphoSitePlus;EPSD	ICGC;COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	P15923	TCF3	P24941	CDK2	S245	S245F	245	Missense	central	0	yes	13.859	0.000	PhosphoSitePlus;EPSD	ICGC	8.148	Loss
CMGC_CDK_CDK2_CDK2_ST	P15923	TCF3	P24941	CDK2	S245	L249P	249	Missense	distal	4	no	13.859	13.747	PhosphoSitePlus;EPSD	ICGC;COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	P15923	TCF3	P24941	CDK2	T308	G302C	302	Missense	distal	-6	no	16.249	16.252	EPSD	ICGC;COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	P15923	TCF3	P24941	CDK2	T308	A314V	314	Missense	distal	6	no	16.249	16.252	EPSD	ICGC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	P15923	TCF3	P24941	CDK2	T308	G303S	303	Missense	distal	-5	no	16.249	16.125	EPSD	ICGC;COSMIC;CCLE	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	P15923	TCF3	P24941	CDK2	S352	S359C	359	Missense	distal	7	no	12.332	13.125	EPSD	ICGC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	P15923	TCF3	P24941	CDK2	S352	S359F	359	Missense	distal	7	no	12.332	13.186	EPSD	ICGC;COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	P15923	TCF3	P24941	CDK2	T355	S359C	359	Missense	distal	4	no	12.891	12.130	EPSD	ICGC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	P15923	TCF3	P24941	CDK2	T355	S359F	359	Missense	distal	4	no	12.891	12.695	EPSD	ICGC;COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	P15923	TCF3	P24941	CDK2	S359	S359C	359	Missense	central	0	yes	14.031	0.000	EPSD	ICGC	8.148	Loss
CMGC_CDK_CDK2_CDK2_ST	P15923	TCF3	P24941	CDK2	S359	S359F	359	Missense	central	0	yes	14.031	0.000	EPSD	ICGC;COSMIC	8.148	Loss
CMGC_CDK_CDK2_CDK2_ST	P15923	TCF3	P24941	CDK2	S379	D383Y	383	Missense	distal	4	no	13.318	13.582	EPSD	ICGC;COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	P15923	TCF3	P24941	CDK2	S379	L386I	386	Missense	distal	7	no	13.318	13.344	EPSD	ICGC;COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	P15923	TCF3	P24941	CDK2	S529	A523P	523	Missense	distal	-6	no	13.756	13.758	EPSD	ICGC;COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	P15923	TCF3	P24941	CDK2	S529	D536E	536	Missense	distal	7	no	13.756	13.114	EPSD	ICGC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	O60271	SPAG9	P24941	CDK2	T226	E225D	225	Missense	proximal	-1	no	12.761	12.732	EPSD	ICGC;COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	O60271	SPAG9	P24941	CDK2	S242	R241H	241	Missense	proximal	-1	no	10.039	9.588	EPSD	ICGC;COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	O60271	SPAG9	P24941	CDK2	S251	P254T	254	Missense	distal	3	no	15.066	14.952	EPSD	ICGC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	O60271	SPAG9	P24941	CDK2	S932	D930G	930	Missense	proximal	-2	no	11.399	10.791	EPSD	ICGC;COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	Q05516	ZBTB16	P24941	CDK2	S253	E250K	250	Missense	distal	-3	no	9.906	9.691	EPSD	ICGC;COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	Q05516	ZBTB16	P24941	CDK2	S253	S256N	256	Missense	distal	3	no	9.906	9.310	EPSD	ICGC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	Q05516	ZBTB16	P24941	CDK2	S256	E250K	250	Missense	distal	-6	no	13.701	13.699	EPSD	ICGC;COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	Q05516	ZBTB16	P24941	CDK2	S256	S256N	256	Missense	central	0	yes	13.701	0.000	EPSD	ICGC	8.148	Loss
CMGC_CDK_CDK2_CDK2_ST	Q05516	ZBTB16	P24941	CDK2	T282	P283L	283	Missense	proximal	1	no	17.614	7.794	EPSD;PhosphoSitePlus	ICGC;COSMIC	8.148	Loss
CMGC_CDK_CDK2_CDK2_ST	Q05516	ZBTB16	P24941	CDK2	T282	R285Q	285	Missense	distal	3	no	17.614	15.871	EPSD;PhosphoSitePlus	ICGC;COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	Q05516	ZBTB16	P24941	CDK2	T282	S287N	287	Missense	distal	5	no	17.614	17.818	EPSD;PhosphoSitePlus	ICGC;COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	Q05516	ZBTB16	P24941	CDK2	T282	S287R	287	Missense	distal	5	no	17.614	17.822	EPSD;PhosphoSitePlus	ICGC;COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	Q05516	ZBTB16	P24941	CDK2	T282	P283Q	283	Missense	proximal	1	no	17.614	9.703	EPSD;PhosphoSitePlus	ICGC;COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	Q05516	ZBTB16	P24941	CDK2	T569	T569M	569	Missense	central	0	yes	9.340	0.000	EPSD	ICGC;COSMIC;CCLE	8.148	Loss
CMGC_CDK_CDK2_CDK2_ST	Q05516	ZBTB16	P24941	CDK2	T569	E575D	575	Missense	distal	6	no	9.340	9.327	EPSD	ICGC;COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	Q05516	ZBTB16	P24941	CDK2	T569	S563I	563	Missense	distal	-6	no	9.340	9.343	EPSD	ICGC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	Q05516	ZBTB16	P24941	CDK2	T597	R594W	594	Missense	distal	-3	no	12.433	12.514	EPSD	ICGC;COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	Q05516	ZBTB16	P24941	CDK2	T597	Y593C	593	Missense	distal	-4	no	12.433	11.216	EPSD	ICGC;COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	P29374	ARID4A	P24941	CDK2	S698	A705S	705	Missense	distal	7	no	8.165	7.629	EPSD	ICGC	8.148	Loss
CMGC_CDK_CDK2_CDK2_ST	P29374	ARID4A	P24941	CDK2	S698	C696F	696	Missense	proximal	-2	no	8.165	8.114	EPSD	ICGC	8.148	Loss
CMGC_CDK_CDK2_CDK2_ST	P29374	ARID4A	P24941	CDK2	S698	D694Y	694	Missense	distal	-4	no	8.165	8.104	EPSD	ICGC;COSMIC	8.148	Loss
CMGC_CDK_CDK2_CDK2_ST	P29374	ARID4A	P24941	CDK2	S789	E785Q	785	Missense	distal	-4	no	12.863	12.415	EPSD	ICGC;COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	P29374	ARID4A	P24941	CDK2	S789	K784T	784	Missense	distal	-5	no	12.863	12.859	EPSD	ICGC;COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	P29374	ARID4A	P24941	CDK2	S864	I869K	869	Missense	distal	5	no	20.135	19.988	PhosphoSitePlus;EPSD	ICGC;COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	P29374	ARID4A	P24941	CDK2	S864	I869V	869	Missense	distal	5	no	20.135	20.010	PhosphoSitePlus;EPSD	ICGC;COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	P29374	ARID4A	P24941	CDK2	S864	R857Q	857	Missense	distal	-7	no	20.135	19.749	PhosphoSitePlus;EPSD	ICGC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	P29374	ARID4A	P24941	CDK2	S1007	Q1013K	1013	Missense	distal	6	no	11.761	11.763	EPSD;PhosphoSitePlus	ICGC;COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	P29374	ARID4A	P24941	CDK2	S1007	P1008Q	1008	Missense	proximal	1	no	11.761	3.849	EPSD;PhosphoSitePlus	ICGC;COSMIC	8.148	Loss
CMGC_CDK_CDK2_CDK2_ST	P29374	ARID4A	P24941	CDK2	T1124	S1121R	1121	Missense	distal	-3	no	16.656	16.749	EPSD;PhosphoSitePlus	ICGC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	P29374	ARID4A	P24941	CDK2	T1124	P1125A	1125	Missense	proximal	1	no	16.656	2.252	EPSD;PhosphoSitePlus	ICGC;COSMIC	8.148	Loss
CMGC_CDK_CDK2_CDK2_ST	P29374	ARID4A	P24941	CDK2	S1140	R1143S	1143	Missense	distal	3	no	15.316	13.632	EPSD;PhosphoSitePlus	ICGC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	P29374	ARID4A	P24941	CDK2	S1140	Q1135E	1135	Missense	distal	-5	no	15.316	15.353	EPSD;PhosphoSitePlus	ICGC;COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	P29374	ARID4A	P24941	CDK2	S1140	R1139Q	1139	Missense	proximal	-1	no	15.316	14.438	EPSD;PhosphoSitePlus	ICGC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	P29374	ARID4A	P24941	CDK2	S1145	R1143S	1143	Missense	proximal	-2	no	15.244	15.828	EPSD;PhosphoSitePlus	ICGC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	P29374	ARID4A	P24941	CDK2	S1145	E1152D	1152	Missense	distal	7	no	15.244	15.886	EPSD;PhosphoSitePlus	ICGC;CCLE	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	Q5TZA2	CROCC	P24941	CDK2	S100	R101H	101	Missense	proximal	1	no	6.165	9.205	EPSD	ICGC;COSMIC;GDSC;CCLE	8.148	Gain
CMGC_CDK_CDK2_CDK2_ST	Q5TZA2	CROCC	P24941	CDK2	S100	E103K	103	Missense	distal	3	no	6.165	8.250	EPSD	ICGC	8.148	Gain
CMGC_CDK_CDK2_CDK2_ST	Q5TZA2	CROCC	P24941	CDK2	S488	L487F	487	Missense	proximal	-1	no	8.091	9.056	EPSD	ICGC;COSMIC	8.148	Gain
CMGC_CDK_CDK2_CDK2_ST	Q5TZA2	CROCC	P24941	CDK2	T492	R497W	497	Missense	distal	5	no	12.216	12.382	EPSD	ICGC;COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	Q5TZA2	CROCC	P24941	CDK2	T492	S499F	499	Missense	distal	7	no	12.216	13.069	EPSD	ICGC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	Q5TZA2	CROCC	P24941	CDK2	T492	R498H	498	Missense	distal	6	no	12.216	12.227	EPSD	ICGC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	Q5TZA2	CROCC	P24941	CDK2	T492	L487F	487	Missense	distal	-5	no	12.216	12.276	EPSD	ICGC;COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	Q5TZA2	CROCC	P24941	CDK2	S494	R497W	497	Missense	distal	3	no	15.424	12.784	EPSD	ICGC;COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	Q5TZA2	CROCC	P24941	CDK2	S494	S499F	499	Missense	distal	5	no	15.424	15.742	EPSD	ICGC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	Q5TZA2	CROCC	P24941	CDK2	S494	R498H	498	Missense	distal	4	no	15.424	15.306	EPSD	ICGC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	Q5TZA2	CROCC	P24941	CDK2	S494	S500P	500	Missense	distal	6	no	15.424	15.422	EPSD	ICGC;COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	Q5TZA2	CROCC	P24941	CDK2	S494	L487F	487	Missense	distal	-7	no	15.424	15.790	EPSD	ICGC;COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	Q5TZA2	CROCC	P24941	CDK2	S499	S500P	500	Missense	proximal	1	no	0.705	11.971	EPSD	ICGC;COSMIC	8.148	Gain
CMGC_CDK_CDK2_CDK2_ST	Q5TZA2	CROCC	P24941	CDK2	S500	G504S	504	Missense	distal	4	no	14.610	14.743	EPSD	ICGC;COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	Q5TZA2	CROCC	P24941	CDK2	S500	R497W	497	Missense	distal	-3	no	14.610	14.691	EPSD	ICGC;COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	Q5TZA2	CROCC	P24941	CDK2	S500	S499F	499	Missense	proximal	-1	no	14.610	15.867	EPSD	ICGC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	Q5TZA2	CROCC	P24941	CDK2	S500	R498H	498	Missense	proximal	-2	no	14.610	14.836	EPSD	ICGC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	Q5TZA2	CROCC	P24941	CDK2	S500	S500P	500	Missense	central	0	yes	14.610	0.000	EPSD	ICGC;COSMIC	8.148	Loss
CMGC_CDK_CDK2_CDK2_ST	Q5TZA2	CROCC	P24941	CDK2	S506	P511S	511	Missense	distal	5	no	16.468	16.368	EPSD	ICGC;COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	Q5TZA2	CROCC	P24941	CDK2	S506	G504S	504	Missense	proximal	-2	no	16.468	16.560	EPSD	ICGC;COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	Q5TZA2	CROCC	P24941	CDK2	S506	S499F	499	Missense	distal	-7	no	16.468	17.020	EPSD	ICGC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	Q5TZA2	CROCC	P24941	CDK2	S506	R508S	508	Missense	proximal	2	no	16.468	16.376	EPSD	ICGC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	Q5TZA2	CROCC	P24941	CDK2	S506	S500P	500	Missense	distal	-6	no	16.468	16.469	EPSD	ICGC;COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	Q5TZA2	CROCC	P24941	CDK2	S512	P511S	511	Missense	proximal	-1	no	10.715	10.244	EPSD	ICGC;COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	Q5TZA2	CROCC	P24941	CDK2	S512	R508S	508	Missense	distal	-4	no	10.715	11.312	EPSD	ICGC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	Q5TZA2	CROCC	P24941	CDK2	S516	P511S	511	Missense	distal	-5	no	8.749	8.705	EPSD	ICGC;COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	Q5TZA2	CROCC	P24941	CDK2	S516	T520M	520	Missense	distal	4	no	8.749	8.045	EPSD	ICGC;COSMIC	8.148	Loss
CMGC_CDK_CDK2_CDK2_ST	Q5TZA2	CROCC	P24941	CDK2	S602	R595Q	595	Missense	distal	-7	no	8.174	7.787	EPSD	ICGC;COSMIC	8.148	Loss
CMGC_CDK_CDK2_CDK2_ST	Q5TZA2	CROCC	P24941	CDK2	S602	N598I	598	Missense	distal	-4	no	8.174	7.885	EPSD	ICGC;COSMIC	8.148	Loss
CMGC_CDK_CDK2_CDK2_ST	Q5TZA2	CROCC	P24941	CDK2	S602	S602R	602	Missense	central	0	yes	8.174	0.000	EPSD	ICGC;COSMIC	8.148	Loss
CMGC_CDK_CDK2_CDK2_ST	Q5TZA2	CROCC	P24941	CDK2	S602	E599K	599	Missense	distal	-3	no	8.174	7.958	EPSD	ICGC	8.148	Loss
CMGC_CDK_CDK2_CDK2_ST	Q5TZA2	CROCC	P24941	CDK2	S1451	G1447S	1447	Missense	distal	-4	no	13.889	14.561	EPSD	ICGC;COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	Q5TZA2	CROCC	P24941	CDK2	S1476	P1477L	1477	Missense	proximal	1	no	14.056	4.236	EPSD	ICGC	8.148	Loss
CMGC_CDK_CDK2_CDK2_ST	Q5TZA2	CROCC	P24941	CDK2	S1608	L1609P	1609	Missense	proximal	1	no	3.399	13.220	EPSD	ICGC	8.148	Gain
CMGC_CDK_CDK2_CDK2_ST	Q5TZA2	CROCC	P24941	CDK2	S1849	R1852L	1852	Missense	distal	3	no	8.402	6.300	EPSD	ICGC	8.148	Loss
CMGC_CDK_CDK2_CDK2_ST	Q5TZA2	CROCC	P24941	CDK2	S1849	A1855S	1855	Missense	distal	6	no	8.402	8.407	EPSD	ICGC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	Q5TZA2	CROCC	P24941	CDK2	S1849	R1846L	1846	Missense	distal	-3	no	8.402	8.142	EPSD	ICGC	8.148	Loss
CMGC_CDK_CDK2_CDK2_ST	Q5TZA2	CROCC	P24941	CDK2	T1911	A1913D	1913	Missense	proximal	2	no	8.886	8.858	EPSD	ICGC;COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	Q5TZA2	CROCC	P24941	CDK2	S1939	E1935D	1935	Missense	distal	-4	no	14.696	14.993	EPSD	ICGC;COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	Q5TZA2	CROCC	P24941	CDK2	S2009	A2006V	2006	Missense	distal	-3	no	16.642	16.843	EPSD	ICGC;COSMIC;GDSC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	Q5TZA2	CROCC	P24941	CDK2	S2009	S2009F	2009	Missense	central	0	yes	16.642	0.000	EPSD	ICGC;COSMIC	8.148	Loss
CMGC_CDK_CDK2_CDK2_ST	Q5TZA2	CROCC	P24941	CDK2	S2009	R2002Q	2002	Missense	distal	-7	no	16.642	16.255	EPSD	ICGC;CCLE	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	Q5TZA2	CROCC	P24941	CDK2	S2009	F2008L	2008	Missense	proximal	-1	no	16.642	15.677	EPSD	ICGC;COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	Q5TZA2	CROCC	P24941	CDK2	S2009	S2009Y	2009	Missense	central	0	yes	16.642	0.000	EPSD	ICGC;COSMIC	8.148	Loss
CMGC_CDK_CDK2_CDK2_ST	Q04637	EIF4G1	P24941	CDK2	S15	P19L	19	Missense	distal	4	no	12.202	12.314	EPSD	ICGC;COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	Q04637	EIF4G1	P24941	CDK2	S15	P14S	14	Missense	proximal	-1	no	12.202	11.731	EPSD	ICGC;COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	Q04637	EIF4G1	P24941	CDK2	T43	A38S	38	Missense	distal	-5	no	9.718	9.649	EPSD	ICGC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	Q04637	EIF4G1	P24941	CDK2	T43	S45F	45	Missense	proximal	2	no	9.718	9.902	EPSD	ICGC;COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	Q04637	EIF4G1	P24941	CDK2	T205	P208S	208	Missense	distal	3	no	12.529	12.564	EPSD	ICGC;COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	Q04637	EIF4G1	P24941	CDK2	T205	P208H	208	Missense	distal	3	no	12.529	13.552	EPSD	ICGC;GDSC;CCLE	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	Q04637	EIF4G1	P24941	CDK2	T207	P208S	208	Missense	proximal	1	no	14.540	3.275	EPSD	ICGC;COSMIC	8.148	Loss
CMGC_CDK_CDK2_CDK2_ST	Q04637	EIF4G1	P24941	CDK2	T207	P208H	208	Missense	proximal	1	no	14.540	7.782	EPSD	ICGC;GDSC;CCLE	8.148	Loss
CMGC_CDK_CDK2_CDK2_ST	Q04637	EIF4G1	P24941	CDK2	T223	P224S	224	Missense	proximal	1	no	15.200	3.934	EPSD	ICGC;COSMIC	8.148	Loss
CMGC_CDK_CDK2_CDK2_ST	Q04637	EIF4G1	P24941	CDK2	S314	P310L	310	Missense	distal	-4	no	13.252	13.193	EPSD	ICGC;COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	Q04637	EIF4G1	P24941	CDK2	S314	P310H	310	Missense	distal	-4	no	13.252	12.648	EPSD	ICGC;COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	Q04637	EIF4G1	P24941	CDK2	S416	E420K	420	Missense	distal	4	no	11.231	11.616	EPSD	ICGC;COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	Q04637	EIF4G1	P24941	CDK2	S450	T449I	449	Missense	proximal	-1	no	14.527	14.773	EPSD	ICGC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	Q04637	EIF4G1	P24941	CDK2	T1179	R1184Q	1184	Missense	distal	5	no	15.298	15.152	EPSD	ICGC;COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	Q9ULX3	NOB1	P24941	CDK2	T121	S115L	115	Missense	distal	-6	no	15.041	15.042	PhosphoSitePlus	ICGC;COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	Q9ULX3	NOB1	P24941	CDK2	S201	D204E	204	Missense	distal	3	no	7.494	9.930	EPSD	ICGC;COSMIC	8.148	Gain
CMGC_CDK_CDK2_CDK2_ST	Q9ULX3	NOB1	P24941	CDK2	T210	D204E	204	Missense	distal	-6	no	13.370	13.375	EPSD	ICGC;COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	Q9ULX3	NOB1	P24941	CDK2	T328	A335T	335	Missense	distal	7	no	13.292	12.603	EPSD	ICGC;COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	Q9ULX3	NOB1	P24941	CDK2	T328	R323L	323	Missense	distal	-5	no	13.292	13.257	EPSD	ICGC;COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	Q9ULX3	NOB1	P24941	CDK2	S371	A368S	368	Missense	distal	-3	no	12.557	12.711	EPSD	ICGC;COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	Q9NRH3	TUBG2	P24941	CDK2	S32	E34D	34	Missense	proximal	2	no	11.518	11.419	EPSD	ICGC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	Q9NRH3	TUBG2	P24941	CDK2	S32	S32N	32	Missense	central	0	yes	11.518	0.000	EPSD	ICGC	8.148	Loss
CMGC_CDK_CDK2_CDK2_ST	Q9NRH3	TUBG2	P24941	CDK2	T45	E43K	43	Missense	proximal	-2	no	10.767	11.368	EPSD	ICGC;COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	Q9NRH3	TUBG2	P24941	CDK2	T45	D49Y	49	Missense	distal	4	no	10.767	11.031	EPSD	ICGC;COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	Q9NRH3	TUBG2	P24941	CDK2	T45	R47C	47	Missense	proximal	2	no	10.767	10.754	EPSD	ICGC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	Q9NRH3	TUBG2	P24941	CDK2	T274	G272V	272	Missense	proximal	-2	no	11.231	11.324	EPSD	ICGC;COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	Q9NRH3	TUBG2	P24941	CDK2	T274	D279E	279	Missense	distal	5	no	11.231	11.136	EPSD	ICGC;COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	Q16204	CCDC6	P24941	CDK2	S52	S52A	52	Missense	central	0	yes	13.550	0.000	EPSD	ICGC;COSMIC	8.148	Loss
CMGC_CDK_CDK2_CDK2_ST	Q16204	CCDC6	P24941	CDK2	S244	R246I	246	Missense	proximal	2	no	14.569	14.388	PhosphoSitePlus	ICGC;COSMIC;GDSC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	Q16204	CCDC6	P24941	CDK2	S244	V239I	239	Missense	distal	-5	no	14.569	14.578	PhosphoSitePlus	ICGC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	Q16204	CCDC6	P24941	CDK2	S254	R260C	260	Missense	distal	6	no	13.770	13.773	EPSD	ICGC;COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	Q16204	CCDC6	P24941	CDK2	S254	M258I	258	Missense	distal	4	no	13.770	14.163	EPSD	ICGC;COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	Q16204	CCDC6	P24941	CDK2	S254	P255T	255	Missense	proximal	1	no	13.770	3.813	EPSD	ICGC;COSMIC	8.148	Loss
CMGC_CDK_CDK2_CDK2_ST	Q16204	CCDC6	P24941	CDK2	S352	P358T	358	Missense	distal	6	no	14.177	14.185	EPSD	ICGC;COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	Q16204	CCDC6	P24941	CDK2	S352	P353T	353	Missense	proximal	1	no	14.177	4.220	EPSD	ICGC	8.148	Loss
CMGC_CDK_CDK2_CDK2_ST	Q16204	CCDC6	P24941	CDK2	S352	P347H	347	Missense	distal	-5	no	14.177	14.224	EPSD	ICGC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	Q16204	CCDC6	P24941	CDK2	T357	P358T	358	Missense	proximal	1	no	12.525	2.567	EPSD	ICGC;COSMIC	8.148	Loss
CMGC_CDK_CDK2_CDK2_ST	Q16204	CCDC6	P24941	CDK2	T357	P353T	353	Missense	distal	-4	no	12.525	12.691	EPSD	ICGC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	Q16204	CCDC6	P24941	CDK2	S359	P358T	358	Missense	proximal	-1	no	13.468	13.205	EPSD	ICGC;COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	Q16204	CCDC6	P24941	CDK2	S367	P368H	368	Missense	proximal	1	no	12.166	5.407	EPSD	ICGC;COSMIC	8.148	Loss
CMGC_CDK_CDK2_CDK2_ST	Q16204	CCDC6	P24941	CDK2	S367	G369C	369	Missense	proximal	2	no	12.166	12.194	EPSD	ICGC;COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	Q16204	CCDC6	P24941	CDK2	S374	T376M	376	Missense	proximal	2	no	8.544	8.933	EPSD	ICGC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	Q16204	CCDC6	P24941	CDK2	S374	P368H	368	Missense	distal	-6	no	8.544	8.548	EPSD	ICGC;COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	Q16204	CCDC6	P24941	CDK2	S374	P381Q	381	Missense	distal	7	no	8.544	8.390	EPSD	ICGC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	Q16204	CCDC6	P24941	CDK2	S374	P381L	381	Missense	distal	7	no	8.544	8.575	EPSD	ICGC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	Q16204	CCDC6	P24941	CDK2	S374	G369C	369	Missense	distal	-5	no	8.544	8.546	EPSD	ICGC;COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	Q16204	CCDC6	P24941	CDK2	T380	T376M	376	Missense	distal	-4	no	14.298	13.383	EPSD	ICGC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	Q16204	CCDC6	P24941	CDK2	T380	L385M	385	Missense	distal	5	no	14.298	14.566	EPSD	ICGC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	Q16204	CCDC6	P24941	CDK2	T380	P381Q	381	Missense	proximal	1	no	14.298	6.386	EPSD	ICGC	8.148	Loss
CMGC_CDK_CDK2_CDK2_ST	Q16204	CCDC6	P24941	CDK2	T380	P381L	381	Missense	proximal	1	no	14.298	4.477	EPSD	ICGC	8.148	Loss
CMGC_CDK_CDK2_CDK2_ST	Q16204	CCDC6	P24941	CDK2	T380	P382Q	382	Missense	proximal	2	no	14.298	14.357	EPSD	ICGC;COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	Q16204	CCDC6	P24941	CDK2	S395	P396L	396	Missense	proximal	1	no	13.293	3.472	EPSD	ICGC;COSMIC	8.148	Loss
CMGC_CDK_CDK2_CDK2_ST	Q16204	CCDC6	P24941	CDK2	S413	H407N	407	Missense	distal	-6	no	13.460	13.456	EPSD	ICGC;COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	Q16204	CCDC6	P24941	CDK2	S413	P420L	420	Missense	distal	7	no	13.460	13.490	EPSD	ICGC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	Q16204	CCDC6	P24941	CDK2	S419	P420L	420	Missense	proximal	1	no	16.162	6.341	EPSD	ICGC	8.148	Loss
CMGC_CDK_CDK2_CDK2_ST	Q16204	CCDC6	P24941	CDK2	S419	R425P	425	Missense	distal	6	no	16.162	16.178	EPSD	ICGC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	Q16204	CCDC6	P24941	CDK2	T427	P420L	420	Missense	distal	-7	no	10.712	10.718	EPSD	ICGC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	Q16204	CCDC6	P24941	CDK2	T427	P430L	430	Missense	distal	3	no	10.712	10.329	EPSD	ICGC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	Q16204	CCDC6	P24941	CDK2	T427	R425P	425	Missense	proximal	-2	no	10.712	11.948	EPSD	ICGC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	Q16204	CCDC6	P24941	CDK2	S431	P437T	437	Missense	distal	6	no	14.185	14.193	EPSD	ICGC;COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	Q16204	CCDC6	P24941	CDK2	S431	P430L	430	Missense	proximal	-1	no	14.185	14.005	EPSD	ICGC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	Q16204	CCDC6	P24941	CDK2	S431	R425P	425	Missense	distal	-6	no	14.185	14.183	EPSD	ICGC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	Q16204	CCDC6	P24941	CDK2	T436	P437T	437	Missense	proximal	1	no	13.555	3.598	EPSD	ICGC;COSMIC	8.148	Loss
CMGC_CDK_CDK2_CDK2_ST	Q16204	CCDC6	P24941	CDK2	T436	P443T	443	Missense	distal	7	no	13.555	13.251	EPSD	ICGC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	Q16204	CCDC6	P24941	CDK2	T436	P440T	440	Missense	distal	4	no	13.555	13.838	EPSD	ICGC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	Q16204	CCDC6	P24941	CDK2	T436	P442S	442	Missense	distal	6	no	13.555	13.557	EPSD	ICGC;COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	Q16204	CCDC6	P24941	CDK2	T462	S464L	464	Missense	proximal	2	no	12.911	12.738	EPSD	ICGC;GDSC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	Q16204	CCDC6	P24941	CDK2	T462	P461H	461	Missense	proximal	-1	no	12.911	13.030	EPSD	ICGC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	Q12959	DLG1	P24941	CDK2	S89	S90P	90	Missense	proximal	1	no	3.392	14.658	EPSD	ICGC;COSMIC	8.148	Gain
CMGC_CDK_CDK2_CDK2_ST	Q12959	DLG1	P24941	CDK2	S102	L101I	101	Missense	proximal	-1	no	15.987	16.149	EPSD	ICGC;COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	Q12959	DLG1	P24941	CDK2	S102	S102R	102	Missense	central	0	yes	15.987	0.000	EPSD	ICGC	8.148	Loss
CMGC_CDK_CDK2_CDK2_ST	Q12959	DLG1	P24941	CDK2	S102	R109M	109	Missense	distal	7	no	15.987	16.042	EPSD	ICGC;COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	Q12959	DLG1	P24941	CDK2	T115	P116T	116	Missense	proximal	1	no	14.720	4.763	EPSD	ICGC	8.148	Loss
CMGC_CDK_CDK2_CDK2_ST	Q12959	DLG1	P24941	CDK2	T115	Y110C	110	Missense	distal	-5	no	14.720	14.776	EPSD	ICGC;COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	Q12959	DLG1	P24941	CDK2	T115	R109M	109	Missense	distal	-6	no	14.720	14.725	EPSD	ICGC;COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	Q12959	DLG1	P24941	CDK2	S122	P116T	116	Missense	distal	-6	no	11.137	11.136	EPSD	ICGC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	Q12959	DLG1	P24941	CDK2	S158	T163K	163	Missense	distal	5	no	14.845	14.817	EPSD;PhosphoSitePlus	ICGC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	Q12959	DLG1	P24941	CDK2	S206	T209K	209	Missense	distal	3	no	6.856	9.678	EPSD	ICGC;COSMIC	8.148	Gain
CMGC_CDK_CDK2_CDK2_ST	Q12959	DLG1	P24941	CDK2	T209	T209K	209	Missense	central	0	yes	16.030	0.000	EPSD	ICGC;COSMIC	8.148	Loss
CMGC_CDK_CDK2_CDK2_ST	Q86T82	USP37	P24941	CDK2	S2	I6M	6	Missense	distal	4	no	16.460	16.068	EPSD	ICGC;COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	Q86T82	USP37	P24941	CDK2	T191	T189A	189	Missense	proximal	-2	no	14.525	14.574	EPSD	ICGC;COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	Q86T82	USP37	P24941	CDK2	T295	P296H	296	Missense	proximal	1	no	11.264	4.505	EPSD	ICGC;COSMIC	8.148	Loss
CMGC_CDK_CDK2_CDK2_ST	Q86T82	USP37	P24941	CDK2	T295	L302V	302	Missense	distal	7	no	11.264	11.492	EPSD	ICGC;COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	Q86T82	USP37	P24941	CDK2	S422	R420T	420	Missense	proximal	-2	no	7.697	8.900	EPSD	ICGC;COSMIC	8.148	Gain
CMGC_CDK_CDK2_CDK2_ST	Q86T82	USP37	P24941	CDK2	S628	T627I	627	Missense	proximal	-1	no	13.885	14.131	PhosphoSitePlus	ICGC;COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	Q86T82	USP37	P24941	CDK2	T631	T627I	627	Missense	distal	-4	no	15.733	15.416	EPSD	ICGC;COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	Q86T82	USP37	P24941	CDK2	T631	F638L	638	Missense	distal	7	no	15.733	15.062	EPSD	ICGC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	Q86T82	USP37	P24941	CDK2	T631	T637N	637	Missense	distal	6	no	15.733	15.729	EPSD	ICGC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	Q86T82	USP37	P24941	CDK2	S735	S734R	734	Missense	proximal	-1	no	14.261	15.303	EPSD	ICGC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	Q86T82	USP37	P24941	CDK2	T738	S734R	734	Missense	distal	-4	no	10.268	9.671	EPSD	ICGC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	Q86T82	USP37	P24941	CDK2	T786	P787L	787	Missense	proximal	1	no	14.347	4.526	EPSD	ICGC;COSMIC	8.148	Loss
CMGC_CDK_CDK2_CDK2_ST	Q86T82	USP37	P24941	CDK2	T786	K782N	782	Missense	distal	-4	no	14.347	14.566	EPSD	ICGC;COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	Q86XL3	ANKLE2	P24941	CDK2	S259	T263K	263	Missense	distal	4	no	16.639	16.758	EPSD	ICGC;COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	Q86XL3	ANKLE2	P24941	CDK2	S268	T272K	272	Missense	distal	4	no	15.872	15.991	EPSD	ICGC;COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	Q86XL3	ANKLE2	P24941	CDK2	S268	T263K	263	Missense	distal	-5	no	15.872	15.876	EPSD	ICGC;COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	Q86XL3	ANKLE2	P24941	CDK2	T406	P407S	407	Missense	proximal	1	no	16.988	5.722	EPSD	ICGC	8.148	Loss
CMGC_CDK_CDK2_CDK2_ST	Q86XL3	ANKLE2	P24941	CDK2	T448	D446N	446	Missense	proximal	-2	no	10.206	8.998	EPSD	ICGC;CCLE	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	Q86XL3	ANKLE2	P24941	CDK2	T448	S441L	441	Missense	distal	-7	no	10.206	10.392	EPSD	ICGC;COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	Q86XL3	ANKLE2	P24941	CDK2	S488	W495L	495	Missense	distal	7	no	13.370	12.511	EPSD	ICGC;COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	Q86XL3	ANKLE2	P24941	CDK2	S496	Q499K	499	Missense	distal	3	no	16.120	18.852	EPSD	ICGC;COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	Q86XL3	ANKLE2	P24941	CDK2	S496	P497T	497	Missense	proximal	1	no	16.120	6.162	EPSD	ICGC;COSMIC	8.148	Loss
CMGC_CDK_CDK2_CDK2_ST	Q86XL3	ANKLE2	P24941	CDK2	S496	W495L	495	Missense	proximal	-1	no	16.120	14.816	EPSD	ICGC;COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	Q86XL3	ANKLE2	P24941	CDK2	S512	P516L	516	Missense	distal	4	no	12.853	12.965	EPSD	ICGC;COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	Q86XL3	ANKLE2	P24941	CDK2	S512	Y509H	509	Missense	distal	-3	no	12.853	12.885	EPSD	ICGC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	Q86XL3	ANKLE2	P24941	CDK2	S512	G511D	511	Missense	proximal	-1	no	12.853	12.560	EPSD	ICGC;COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	Q86XL3	ANKLE2	P24941	CDK2	S512	D515E	515	Missense	distal	3	no	12.853	15.289	EPSD	ICGC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	Q86XL3	ANKLE2	P24941	CDK2	T541	A547E	547	Missense	distal	6	no	15.373	15.375	EPSD	ICGC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	Q86XL3	ANKLE2	P24941	CDK2	T541	K537N	537	Missense	distal	-4	no	15.373	15.592	EPSD	ICGC;COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	Q86XL3	ANKLE2	P24941	CDK2	T541	A547T	547	Missense	distal	6	no	15.373	15.385	EPSD	ICGC;COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	Q86XL3	ANKLE2	P24941	CDK2	S556	E559Q	559	Missense	distal	3	no	8.360	7.713	EPSD	ICGC;COSMIC	8.148	Loss
CMGC_CDK_CDK2_CDK2_ST	Q9H3P2	NELFA	P24941	CDK2	S393	T398M	398	Missense	distal	5	no	13.925	14.258	EPSD	ICGC;COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	Q9H3P2	NELFA	P24941	CDK2	S393	T398K	398	Missense	distal	5	no	13.925	13.896	EPSD	ICGC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	Q9H3P2	NELFA	P24941	CDK2	T396	T398M	398	Missense	proximal	2	no	12.911	13.300	EPSD	ICGC;COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	Q9H3P2	NELFA	P24941	CDK2	T396	T398K	398	Missense	proximal	2	no	12.911	12.947	EPSD	ICGC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	Q9H3P2	NELFA	P24941	CDK2	T399	T398M	398	Missense	proximal	-1	no	13.055	14.368	EPSD	ICGC;COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	Q9H3P2	NELFA	P24941	CDK2	T399	T398K	398	Missense	proximal	-1	no	13.055	13.218	EPSD	ICGC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	Q9UKY1	ZHX1	P24941	CDK2	T9	R5Q	5	Missense	distal	-4	no	11.035	11.059	EPSD	ICGC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	Q9UKY1	ZHX1	P24941	CDK2	T9	S3R	3	Missense	distal	-6	no	11.035	11.038	EPSD	ICGC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	Q9UKY1	ZHX1	P24941	CDK2	T36	R42T	42	Missense	distal	6	no	15.400	15.424	EPSD	ICGC;COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	Q9UKY1	ZHX1	P24941	CDK2	T36	N40K	40	Missense	distal	4	no	15.400	15.822	EPSD	ICGC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	Q9UKY1	ZHX1	P24941	CDK2	T36	A43E	43	Missense	distal	7	no	15.400	15.060	EPSD	ICGC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	Q9UKY1	ZHX1	P24941	CDK2	T36	G31C	31	Missense	distal	-5	no	15.400	15.401	EPSD	ICGC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	Q9UKY1	ZHX1	P24941	CDK2	S58	D59G	59	Missense	proximal	1	no	7.841	8.772	EPSD	ICGC;COSMIC	8.148	Gain
CMGC_CDK_CDK2_CDK2_ST	Q9UKY1	ZHX1	P24941	CDK2	T252	V250A	250	Missense	proximal	-2	no	11.121	11.787	EPSD	ICGC;COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	Q9UKY1	ZHX1	P24941	CDK2	T568	P563S	563	Missense	distal	-5	no	16.490	16.446	PhosphoSitePlus	ICGC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	Q9UKY1	ZHX1	P24941	CDK2	S648	G645A	645	Missense	distal	-3	no	11.741	11.579	EPSD	ICGC;COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	Q9UKY1	ZHX1	P24941	CDK2	S653	P656A	656	Missense	distal	3	no	8.774	8.262	EPSD	ICGC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	Q9UKY1	ZHX1	P24941	CDK2	T668	L672M	672	Missense	distal	4	no	12.713	12.180	EPSD	ICGC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	Q9UKY1	ZHX1	P24941	CDK2	T668	P669T	669	Missense	proximal	1	no	12.713	2.756	EPSD	ICGC	8.148	Loss
CMGC_CDK_CDK2_CDK2_ST	Q9UKY1	ZHX1	P24941	CDK2	S686	P687Q	687	Missense	proximal	1	no	15.776	7.864	EPSD	ICGC	8.148	Loss
CMGC_CDK_CDK2_CDK2_ST	Q9UKY1	ZHX1	P24941	CDK2	S774	I776K	776	Missense	proximal	2	no	8.270	8.152	EPSD	ICGC;COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	P08621	SNRNP70	P24941	CDK2	S140	M134I	134	Missense	distal	-6	no	8.898	8.893	EPSD	ICGC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	P08621	SNRNP70	P24941	CDK2	S226	R233T	233	Missense	distal	7	no	15.254	14.460	PhosphoSitePlus	ICGC;COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	P08621	SNRNP70	P24941	CDK2	S226	R233K	233	Missense	distal	7	no	15.254	14.478	PhosphoSitePlus	ICGC;COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	P08621	SNRNP70	P24941	CDK2	S226	G224V	224	Missense	proximal	-2	no	15.254	15.347	PhosphoSitePlus	ICGC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	P08621	SNRNP70	P24941	CDK2	S226	G224S	224	Missense	proximal	-2	no	15.254	15.345	PhosphoSitePlus	ICGC;COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	P08621	SNRNP70	P24941	CDK2	S257	R258Q	258	Missense	proximal	1	no	6.490	8.376	EPSD	ICGC;COSMIC	8.148	Gain
CMGC_CDK_CDK2_CDK2_ST	P08621	SNRNP70	P24941	CDK2	S293	R294P	294	Missense	proximal	1	no	5.469	15.268	EPSD	ICGC	8.148	Gain
CMGC_CDK_CDK2_CDK2_ST	Q14676	MDC1	P24941	CDK2	S108	P109S	109	Missense	proximal	1	no	13.497	2.231	EPSD	ICGC;GDSC;CCLE	8.148	Loss
CMGC_CDK_CDK2_CDK2_ST	Q14676	MDC1	P24941	CDK2	S108	R114C	114	Missense	distal	6	no	13.497	13.499	EPSD	ICGC;COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	Q14676	MDC1	P24941	CDK2	S202	G207D	207	Missense	distal	5	no	13.551	13.598	EPSD	ICGC;COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	Q14676	MDC1	P24941	CDK2	T341	I338M	338	Missense	distal	-3	no	14.347	14.695	EPSD;PhosphoSitePlus	ICGC;COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	Q14676	MDC1	P24941	CDK2	T725	P727L	727	Missense	proximal	2	no	9.897	9.790	EPSD	ICGC;COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	Q14676	MDC1	P24941	CDK2	T770	D769G	769	Missense	proximal	-1	no	7.941	8.234	EPSD	ICGC;COSMIC	8.148	Gain
CMGC_CDK_CDK2_CDK2_ST	Q14676	MDC1	P24941	CDK2	S780	P782L	782	Missense	proximal	2	no	15.760	15.653	EPSD	ICGC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	Q14676	MDC1	P24941	CDK2	S882	P883S	883	Missense	proximal	1	no	14.584	3.318	EPSD	ICGC;COSMIC	8.148	Loss
CMGC_CDK_CDK2_CDK2_ST	Q14676	MDC1	P24941	CDK2	S964	E968K	968	Missense	distal	4	no	12.779	13.164	EPSD	ICGC;COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	Q14676	MDC1	P24941	CDK2	S964	T966K	966	Missense	proximal	2	no	12.779	12.815	EPSD	ICGC;COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	Q14676	MDC1	P24941	CDK2	S964	P969T	969	Missense	distal	5	no	12.779	12.753	EPSD	ICGC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	Q14676	MDC1	P24941	CDK2	T966	E968K	968	Missense	proximal	2	no	10.668	10.430	EPSD	ICGC;COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	Q14676	MDC1	P24941	CDK2	T966	T966K	966	Missense	central	0	yes	10.668	0.000	EPSD	ICGC;COSMIC	8.148	Loss
CMGC_CDK_CDK2_CDK2_ST	Q14676	MDC1	P24941	CDK2	T966	P969T	969	Missense	distal	3	no	10.668	10.553	EPSD	ICGC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	Q14676	MDC1	P24941	CDK2	S990	G987R	987	Missense	distal	-3	no	10.018	10.103	EPSD	ICGC;COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	Q14676	MDC1	P24941	CDK2	S998	Q1003E	1003	Missense	distal	5	no	17.115	17.234	EPSD	ICGC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	Q14676	MDC1	P24941	CDK2	S1068	P1063S	1063	Missense	distal	-5	no	13.716	13.671	EPSD;PhosphoSitePlus	ICGC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	Q14676	MDC1	P24941	CDK2	T1198	S1194Y	1194	Missense	distal	-4	no	12.162	12.273	EPSD	ICGC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	Q14676	MDC1	P24941	CDK2	T1280	S1276P	1276	Missense	distal	-4	no	12.563	12.208	EPSD	ICGC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	Q14676	MDC1	P24941	CDK2	T1343	V1342F	1342	Missense	proximal	-1	no	12.135	12.964	EPSD	ICGC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	Q14676	MDC1	P24941	CDK2	T1526	S1522P	1522	Missense	distal	-4	no	12.329	11.975	EPSD	ICGC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	Q14676	MDC1	P24941	CDK2	T1548	S1542F	1542	Missense	distal	-6	no	13.319	13.324	EPSD	ICGC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	Q14676	MDC1	P24941	CDK2	T1649	P1655R	1655	Missense	distal	6	no	11.947	11.931	EPSD	ICGC;COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	Q14676	MDC1	P24941	CDK2	S1702	Q1708L	1708	Missense	distal	6	no	11.919	11.914	EPSD	ICGC;COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	Q14676	MDC1	P24941	CDK2	S1702	P1709S	1709	Missense	distal	7	no	11.919	11.767	EPSD	ICGC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	Q14676	MDC1	P24941	CDK2	S1711	Q1708L	1708	Missense	distal	-3	no	13.926	13.797	EPSD	ICGC;COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	Q14676	MDC1	P24941	CDK2	S1711	P1709S	1709	Missense	proximal	-2	no	13.926	13.275	EPSD	ICGC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	Q14676	MDC1	P24941	CDK2	S1775	A1774D	1774	Missense	proximal	-1	no	14.242	15.268	EPSD	ICGC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	Q14676	MDC1	P24941	CDK2	S1775	A1769V	1769	Missense	distal	-6	no	14.242	14.245	EPSD	ICGC;COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	Q14676	MDC1	P24941	CDK2	T1781	A1774D	1774	Missense	distal	-7	no	12.270	12.347	EPSD	ICGC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	Q14676	MDC1	P24941	CDK2	T1800	A1794S	1794	Missense	distal	-6	no	11.916	11.917	EPSD	ICGC;COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	Q14676	MDC1	P24941	CDK2	T1800	S1797C	1797	Missense	distal	-3	no	11.916	11.924	EPSD	ICGC;COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	Q14676	MDC1	P24941	CDK2	T1800	S1797L	1797	Missense	distal	-3	no	11.916	11.750	EPSD	ICGC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	Q14676	MDC1	P24941	CDK2	S1820	L1815I	1815	Missense	distal	-5	no	11.067	11.094	EPSD	ICGC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	Q14676	MDC1	P24941	CDK2	S1820	M1818T	1818	Missense	proximal	-2	no	11.067	13.118	EPSD	ICGC;COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	Q8WXE1	ATRIP	P24941	CDK2	T26	R33P	33	Missense	distal	7	no	10.946	10.456	EPSD	ICGC;COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	Q8WXE1	ATRIP	P24941	CDK2	T26	G25S	25	Missense	proximal	-1	no	10.946	9.426	EPSD	ICGC;COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	Q8WXE1	ATRIP	P24941	CDK2	S224	A217S	217	Missense	distal	-7	no	15.669	15.325	PhosphoSitePlus	ICGC;COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	Q8WXE1	ATRIP	P24941	CDK2	S224	A217V	217	Missense	distal	-7	no	15.669	15.524	PhosphoSitePlus	ICGC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	Q8WXE1	ATRIP	P24941	CDK2	S239	K234N	234	Missense	distal	-5	no	12.341	12.357	EPSD	ICGC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	P06748	NPM1	P24941	CDK2	S10	M9I	9	Missense	proximal	-1	no	16.787	15.720	EPSD	ICGC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	P06748	NPM1	P24941	CDK2	S10	D3H	3	Missense	distal	-7	no	16.787	16.669	EPSD	ICGC;COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	P06748	NPM1	P24941	CDK2	S70	Y67D	67	Missense	distal	-3	no	19.803	19.753	PhosphoSitePlus;EPSD	ICGC;COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	P06748	NPM1	P24941	CDK2	S70	E68K	68	Missense	proximal	-2	no	19.803	20.404	PhosphoSitePlus;EPSD	ICGC;COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	P06748	NPM1	P24941	CDK2	S70	M65L	65	Missense	distal	-5	no	19.803	19.707	PhosphoSitePlus;EPSD	ICGC;GDSC;CCLE	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	P06748	NPM1	P24941	CDK2	T95	V99F	99	Missense	distal	4	no	14.238	13.828	EPSD	ICGC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	P06748	NPM1	P24941	CDK2	T95	V99L	99	Missense	distal	4	no	14.238	14.123	EPSD	ICGC;COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	P06748	NPM1	P24941	CDK2	T95	L102F	102	Missense	distal	7	no	14.238	14.909	EPSD	ICGC;COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	P06748	NPM1	P24941	CDK2	T95	G90R	90	Missense	distal	-5	no	14.238	14.205	EPSD	ICGC;COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	P06748	NPM1	P24941	CDK2	T95	S88F	88	Missense	distal	-7	no	14.238	14.789	EPSD	ICGC;COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	P06748	NPM1	P24941	CDK2	T95	V99A	99	Missense	distal	4	no	14.238	14.051	EPSD	ICGC;COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	P06748	NPM1	P24941	CDK2	S106	V99F	99	Missense	distal	-7	no	9.382	9.734	EPSD	ICGC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	P06748	NPM1	P24941	CDK2	S106	V99L	99	Missense	distal	-7	no	9.382	9.368	EPSD	ICGC;COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	P06748	NPM1	P24941	CDK2	S106	L102F	102	Missense	distal	-4	no	9.382	8.833	EPSD	ICGC;COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	P06748	NPM1	P24941	CDK2	S106	S112I	112	Missense	distal	6	no	9.382	9.381	EPSD	ICGC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	P06748	NPM1	P24941	CDK2	S106	V99A	99	Missense	distal	-7	no	9.382	9.527	EPSD	ICGC;COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	P06748	NPM1	P24941	CDK2	S125	E131D	131	Missense	distal	6	no	11.293	11.281	EPSD	ICGC;COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	P06748	NPM1	P24941	CDK2	T199	R197G	197	Missense	proximal	-2	no	16.152	16.646	EPSD;PhosphoSitePlus	ICGC;COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	P06748	NPM1	P24941	CDK2	T199	A204T	204	Missense	distal	5	no	16.152	16.117	EPSD;PhosphoSitePlus	ICGC;COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	P06748	NPM1	P24941	CDK2	T199	P200A	200	Missense	proximal	1	no	16.152	1.749	EPSD;PhosphoSitePlus	ICGC	8.148	Loss
CMGC_CDK_CDK2_CDK2_ST	Q9BZL4	PPP1R12C	P24941	CDK2	T290	L289M	289	Missense	proximal	-1	no	7.367	8.596	EPSD	ICGC	8.148	Gain
CMGC_CDK_CDK2_CDK2_ST	Q9BZL4	PPP1R12C	P24941	CDK2	S399	H402Q	402	Missense	distal	3	no	15.462	14.415	EPSD	ICGC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	Q9BZL4	PPP1R12C	P24941	CDK2	S404	H402Q	402	Missense	proximal	-2	no	11.770	12.213	EPSD	ICGC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	Q9BZL4	PPP1R12C	P24941	CDK2	S407	H402Q	402	Missense	distal	-5	no	15.378	15.331	EPSD	ICGC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	Q9BZL4	PPP1R12C	P24941	CDK2	T472	L468I	468	Missense	distal	-4	no	11.320	11.227	EPSD	ICGC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	Q9BZL4	PPP1R12C	P24941	CDK2	T474	L468I	468	Missense	distal	-6	no	14.682	14.684	EPSD	ICGC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	Q9BZL4	PPP1R12C	P24941	CDK2	T474	R467H	467	Missense	distal	-7	no	14.682	14.462	EPSD	ICGC;COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	Q9BZL4	PPP1R12C	P24941	CDK2	S509	V515I	515	Missense	distal	6	no	18.481	18.482	PhosphoSitePlus	ICGC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	Q9BZL4	PPP1R12C	P24941	CDK2	S509	P510T	510	Missense	proximal	1	no	18.481	8.523	PhosphoSitePlus	ICGC;COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	Q9BZL4	PPP1R12C	P24941	CDK2	S544	K547I	547	Missense	distal	3	no	9.059	5.684	EPSD	ICGC;COSMIC	8.148	Loss
CMGC_CDK_CDK2_CDK2_ST	Q9BZL4	PPP1R12C	P24941	CDK2	S544	R551H	551	Missense	distal	7	no	9.059	8.701	EPSD	ICGC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	Q9BZL4	PPP1R12C	P24941	CDK2	S544	S550F	550	Missense	distal	6	no	9.059	9.040	EPSD	ICGC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	Q14194	CRMP1	P24941	CDK2	S304	V302M	302	Missense	proximal	-2	no	11.035	9.601	EPSD	ICGC;COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	Q14194	CRMP1	P24941	CDK2	S304	A300V	300	Missense	distal	-4	no	11.035	11.046	EPSD	ICGC;COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	Q14194	CRMP1	P24941	CDK2	S304	S308N	308	Missense	distal	4	no	11.035	11.002	EPSD	ICGC;COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	Q14194	CRMP1	P24941	CDK2	S304	A299E	299	Missense	distal	-5	no	11.035	11.048	EPSD	ICGC;COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	Q14194	CRMP1	P24941	CDK2	S304	A299T	299	Missense	distal	-5	no	11.035	11.009	EPSD	ICGC;COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	Q14194	CRMP1	P24941	CDK2	S304	A299V	299	Missense	distal	-5	no	11.035	11.042	EPSD	ICGC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	Q14194	CRMP1	P24941	CDK2	S308	V302M	302	Missense	distal	-6	no	13.825	13.830	EPSD	ICGC;COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	Q14194	CRMP1	P24941	CDK2	S308	S308N	308	Missense	central	0	yes	13.825	0.000	EPSD	ICGC;COSMIC	8.148	Loss
CMGC_CDK_CDK2_CDK2_ST	Q14194	CRMP1	P24941	CDK2	S308	T312N	312	Missense	distal	4	no	13.825	13.522	EPSD	ICGC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	Q14194	CRMP1	P24941	CDK2	S308	D315E	315	Missense	distal	7	no	13.825	13.182	EPSD	ICGC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	Q14194	CRMP1	P24941	CDK2	S522	P528H	528	Missense	distal	6	no	15.211	15.206	EPSD	ICGC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	Q13416	ORC2	P24941	CDK2	T116	S111L	111	Missense	distal	-5	no	15.988	16.044	PhosphoSitePlus;EPSD	ICGC;COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	Q13416	ORC2	P24941	CDK2	T116	P117S	117	Missense	proximal	1	no	15.988	4.722	PhosphoSitePlus;EPSD	ICGC	8.148	Loss
CMGC_CDK_CDK2_CDK2_ST	Q13416	ORC2	P24941	CDK2	S280	R273H	273	Missense	distal	-7	no	14.755	14.535	EPSD	ICGC;COSMIC;CCLE	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	Q13416	ORC2	P24941	CDK2	S280	L287I	287	Missense	distal	7	no	14.755	14.782	EPSD	ICGC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	Q13416	ORC2	P24941	CDK2	S280	L276F	276	Missense	distal	-4	no	14.755	14.206	EPSD	ICGC;COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	Q96II8	LRCH3	P24941	CDK2	S16	A20T	20	Missense	distal	4	no	8.306	8.549	EPSD	ICGC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	Q96II8	LRCH3	P24941	CDK2	S16	G22E	22	Missense	distal	6	no	8.306	8.314	EPSD	ICGC;COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	Q96II8	LRCH3	P24941	CDK2	S16	G17D	17	Missense	proximal	1	no	8.306	7.374	EPSD	ICGC;CCLE	8.148	Loss
CMGC_CDK_CDK2_CDK2_ST	Q96II8	LRCH3	P24941	CDK2	S255	Q254E	254	Missense	proximal	-1	no	12.407	13.500	EPSD	ICGC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	Q96II8	LRCH3	P24941	CDK2	S255	P257H	257	Missense	proximal	2	no	12.407	12.485	EPSD	ICGC;COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	Q96II8	LRCH3	P24941	CDK2	S318	S318C	318	Missense	central	0	yes	10.169	0.000	EPSD	ICGC;COSMIC	8.148	Loss
CMGC_CDK_CDK2_CDK2_ST	Q96II8	LRCH3	P24941	CDK2	S324	S318C	318	Missense	distal	-6	no	10.108	10.114	EPSD	ICGC;COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	Q96II8	LRCH3	P24941	CDK2	S352	R349Q	349	Missense	distal	-3	no	8.581	8.450	EPSD	ICGC;COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	Q96II8	LRCH3	P24941	CDK2	S352	G359C	359	Missense	distal	7	no	8.581	8.552	EPSD	ICGC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	Q96II8	LRCH3	P24941	CDK2	S352	R350T	350	Missense	proximal	-2	no	8.581	9.783	EPSD	ICGC;COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	Q96II8	LRCH3	P24941	CDK2	S628	A627S	627	Missense	proximal	-1	no	11.754	11.553	EPSD	ICGC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	Q12800	TFCP2	P24941	CDK2	T132	Q135K	135	Missense	distal	3	no	5.821	8.553	EPSD	ICGC	8.148	Gain
CMGC_CDK_CDK2_CDK2_ST	Q12800	TFCP2	P24941	CDK2	T258	Y265F	265	Missense	distal	7	no	16.635	17.067	EPSD;PhosphoSitePlus	ICGC;COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	Q12800	TFCP2	P24941	CDK2	S289	V286A	286	Missense	distal	-3	no	12.343	12.142	PhosphoSitePlus;EPSD	ICGC;COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	Q12800	TFCP2	P24941	CDK2	S291	V286A	286	Missense	distal	-5	no	14.952	14.946	EPSD;PhosphoSitePlus	ICGC;COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	Q12800	TFCP2	P24941	CDK2	S291	S297F	297	Missense	distal	6	no	14.952	14.933	EPSD;PhosphoSitePlus	ICGC;COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	Q12800	TFCP2	P24941	CDK2	S309	G304E	304	Missense	distal	-5	no	18.016	17.973	EPSD;PhosphoSitePlus	ICGC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	Q12800	TFCP2	P24941	CDK2	S309	P310S	310	Missense	proximal	1	no	18.016	6.750	EPSD;PhosphoSitePlus	ICGC;COSMIC	8.148	Loss
CMGC_CDK_CDK2_CDK2_ST	Q02535	ID3	P24941	CDK2	S5	P6L	6	Missense	proximal	1	no	12.741	2.921	PhosphoSitePlus	ICGC;COSMIC	8.148	Loss
CMGC_CDK_CDK2_CDK2_ST	Q02535	ID3	P24941	CDK2	S5	P6T	6	Missense	proximal	1	no	12.741	2.784	PhosphoSitePlus	ICGC	8.148	Loss
CMGC_CDK_CDK2_CDK2_ST	P06400	RB1	P24941	CDK2	T5	A10S	10	Missense	distal	5	no	12.968	12.857	EPSD	ICGC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	P06400	RB1	P24941	CDK2	T5	A11T	11	Missense	distal	6	no	12.968	12.980	EPSD	ICGC;COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	P06400	RB1	P24941	CDK2	S230	D224E	224	Missense	distal	-6	no	12.051	12.055	EPSD	ICGC;COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	P06400	RB1	P24941	CDK2	S249	R251L	251	Missense	proximal	2	no	15.721	15.456	EPSD;PhosphoSitePlus	ICGC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	P06400	RB1	P24941	CDK2	S249	G256C	256	Missense	distal	7	no	15.721	15.692	EPSD;PhosphoSitePlus	ICGC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	P06400	RB1	P24941	CDK2	T252	R251L	251	Missense	proximal	-1	no	15.433	14.683	EPSD;PhosphoSitePlus	ICGC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	P06400	RB1	P24941	CDK2	T252	G256C	256	Missense	distal	4	no	15.433	14.806	EPSD;PhosphoSitePlus	ICGC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	P06400	RB1	P24941	CDK2	T356	Q354H	354	Missense	proximal	-2	no	17.127	16.685	PhosphoSitePlus;EPSD	ICGC;COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	P06400	RB1	P24941	CDK2	S567	L572I	572	Missense	distal	5	no	12.510	12.562	EPSD;PhosphoSitePlus	ICGC;COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	P06400	RB1	P24941	CDK2	S567	D571Y	571	Missense	distal	4	no	12.510	12.774	EPSD;PhosphoSitePlus	ICGC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	P06400	RB1	P24941	CDK2	S567	W563L	563	Missense	distal	-4	no	12.510	13.452	EPSD;PhosphoSitePlus	ICGC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	P06400	RB1	P24941	CDK2	S567	A562P	562	Missense	distal	-5	no	12.510	12.485	EPSD;PhosphoSitePlus	ICGC;COSMIC;GDSC;CCLE	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	P06400	RB1	P24941	CDK2	S567	L564F	564	Missense	distal	-3	no	12.510	12.767	EPSD;PhosphoSitePlus	ICGC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	P06400	RB1	P24941	CDK2	S780	P783L	783	Missense	distal	3	no	13.523	13.140	EPSD	ICGC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	P06400	RB1	P24941	CDK2	S788	P783L	783	Missense	distal	-5	no	15.922	15.934	EPSD	ICGC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	P06400	RB1	P24941	CDK2	S795	L797S	797	Missense	proximal	2	no	14.101	14.274	EPSD	ICGC;COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	P06400	RB1	P24941	CDK2	S795	G801E	801	Missense	distal	6	no	14.101	14.109	EPSD	ICGC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	O00267	SUPT5H	P24941	CDK2	S36	E37G	37	Missense	proximal	1	no	8.329	10.183	EPSD	ICGC;COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	O00267	SUPT5H	P24941	CDK2	S36	R30Q	30	Missense	distal	-6	no	8.329	8.330	EPSD	ICGC;COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	O00267	SUPT5H	P24941	CDK2	S36	S36N	36	Missense	central	0	yes	8.329	0.000	EPSD	ICGC;COSMIC	8.148	Loss
CMGC_CDK_CDK2_CDK2_ST	O00267	SUPT5H	P24941	CDK2	S36	P42T	42	Missense	distal	6	no	8.329	8.337	EPSD	ICGC;COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	O00267	SUPT5H	P24941	CDK2	S120	A122S	122	Missense	proximal	2	no	9.341	9.383	EPSD	ICGC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	O00267	SUPT5H	P24941	CDK2	S120	V113F	113	Missense	distal	-7	no	9.341	9.693	EPSD	ICGC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	O00267	SUPT5H	P24941	CDK2	S120	V114F	114	Missense	distal	-6	no	9.341	9.344	EPSD	ICGC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	O00267	SUPT5H	P24941	CDK2	S120	D118Y	118	Missense	proximal	-2	no	9.341	8.912	EPSD	ICGC;COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	O00267	SUPT5H	P24941	CDK2	S391	E394K	394	Missense	distal	3	no	6.446	8.532	EPSD	ICGC	8.148	Gain
CMGC_CDK_CDK2_CDK2_ST	O00267	SUPT5H	P24941	CDK2	S666	A663V	663	Missense	distal	-3	no	13.176	13.377	EPSD;PhosphoSitePlus	ICGC;COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	O00267	SUPT5H	P24941	CDK2	S666	P667L	667	Missense	proximal	1	no	13.176	3.355	EPSD;PhosphoSitePlus	ICGC;COSMIC	8.148	Loss
CMGC_CDK_CDK2_CDK2_ST	O00267	SUPT5H	P24941	CDK2	S671	P667L	667	Missense	distal	-4	no	15.389	15.331	EPSD	ICGC;COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	O00267	SUPT5H	P24941	CDK2	S686	G692C	692	Missense	distal	6	no	14.410	14.407	EPSD	ICGC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	O00267	SUPT5H	P24941	CDK2	S686	G690S	690	Missense	distal	4	no	14.410	14.543	EPSD	ICGC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	O00267	SUPT5H	P24941	CDK2	S686	P687T	687	Missense	proximal	1	no	14.410	4.452	EPSD	ICGC;COSMIC	8.148	Loss
CMGC_CDK_CDK2_CDK2_ST	O00267	SUPT5H	P24941	CDK2	S691	G692C	692	Missense	proximal	1	no	8.160	-3.457	EPSD	ICGC	8.148	Loss
CMGC_CDK_CDK2_CDK2_ST	O00267	SUPT5H	P24941	CDK2	S691	G690S	690	Missense	proximal	-1	no	8.160	6.641	EPSD	ICGC	8.148	Loss
CMGC_CDK_CDK2_CDK2_ST	O00267	SUPT5H	P24941	CDK2	S691	P687T	687	Missense	distal	-4	no	8.160	8.327	EPSD	ICGC;COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	O00267	SUPT5H	P24941	CDK2	S695	G692C	692	Missense	distal	-3	no	8.189	8.188	EPSD	ICGC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	O00267	SUPT5H	P24941	CDK2	S695	G690S	690	Missense	distal	-5	no	8.189	8.065	EPSD	ICGC	8.148	Loss
CMGC_CDK_CDK2_CDK2_ST	O00267	SUPT5H	P24941	CDK2	S730	A727S	727	Missense	distal	-3	no	8.367	8.521	EPSD	ICGC;COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	O00267	SUPT5H	P24941	CDK2	T768	S763A	763	Missense	distal	-5	no	13.954	14.023	EPSD	ICGC;COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	O00267	SUPT5H	P24941	CDK2	T768	M761I	761	Missense	distal	-7	no	13.954	13.647	EPSD	ICGC;GDSC;CCLE	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	O00267	SUPT5H	P24941	CDK2	T775	M777I	777	Missense	proximal	2	no	13.036	12.802	PhosphoSitePlus;EPSD	ICGC;COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	O00267	SUPT5H	P24941	CDK2	T775	G781V	781	Missense	distal	6	no	13.036	13.046	PhosphoSitePlus;EPSD	ICGC;COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	O00267	SUPT5H	P24941	CDK2	S780	M777I	777	Missense	distal	-3	no	11.206	10.857	EPSD	ICGC;COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	O00267	SUPT5H	P24941	CDK2	S780	G781V	781	Missense	proximal	1	no	11.206	1.606	EPSD	ICGC;COSMIC	8.148	Loss
CMGC_CDK_CDK2_CDK2_ST	O00267	SUPT5H	P24941	CDK2	S780	R783Q	783	Missense	distal	3	no	11.206	9.462	EPSD	ICGC;COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	O00267	SUPT5H	P24941	CDK2	T784	M777I	777	Missense	distal	-7	no	13.978	13.672	EPSD	ICGC;COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	O00267	SUPT5H	P24941	CDK2	T784	G781V	781	Missense	distal	-3	no	13.978	14.018	EPSD	ICGC;COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	O00267	SUPT5H	P24941	CDK2	T784	R783Q	783	Missense	proximal	-1	no	13.978	13.100	EPSD	ICGC;COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	O00267	SUPT5H	P24941	CDK2	T791	R798C	798	Missense	distal	7	no	12.170	12.322	EPSD;PhosphoSitePlus	ICGC;COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	O00267	SUPT5H	P24941	CDK2	T791	L793F	793	Missense	proximal	2	no	12.170	12.528	EPSD;PhosphoSitePlus	ICGC;COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	O00267	SUPT5H	P24941	CDK2	T799	T806M	806	Missense	distal	7	no	10.863	11.712	EPSD	ICGC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	O00267	SUPT5H	P24941	CDK2	T799	R798C	798	Missense	proximal	-1	no	10.863	10.165	EPSD	ICGC;COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	O00267	SUPT5H	P24941	CDK2	T799	L793F	793	Missense	distal	-6	no	10.863	10.867	EPSD	ICGC;COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	O00267	SUPT5H	P24941	CDK2	T799	G803D	803	Missense	distal	4	no	10.863	10.918	EPSD	ICGC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	O00267	SUPT5H	P24941	CDK2	S804	T806M	806	Missense	proximal	2	no	7.995	8.384	EPSD	ICGC	8.148	Gain
CMGC_CDK_CDK2_CDK2_ST	O00267	SUPT5H	P24941	CDK2	T806	T806M	806	Missense	central	0	yes	17.093	0.000	EPSD	ICGC	8.148	Loss
CMGC_CDK_CDK2_CDK2_ST	O00267	SUPT5H	P24941	CDK2	T806	G803D	803	Missense	distal	-3	no	17.093	17.054	EPSD	ICGC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	O00267	SUPT5H	P24941	CDK2	T814	T814I	814	Missense	central	0	yes	13.463	0.000	EPSD	ICGC;COSMIC	8.148	Loss
CMGC_CDK_CDK2_CDK2_ST	O00267	SUPT5H	P24941	CDK2	T814	P815F	815	Missense	proximal	1	no	13.463	-1.347	EPSD	ICGC	8.148	Loss
CMGC_CDK_CDK2_CDK2_ST	O00267	SUPT5H	P24941	CDK2	T828	P829L	829	Missense	proximal	1	no	15.154	5.333	EPSD	ICGC	8.148	Loss
CMGC_CDK_CDK2_CDK2_ST	O00267	SUPT5H	P24941	CDK2	T828	P823H	823	Missense	distal	-5	no	15.154	15.201	EPSD	ICGC;COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	O00267	SUPT5H	P24941	CDK2	T854	P857H	857	Missense	distal	3	no	13.972	14.994	EPSD	ICGC;COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	O00267	SUPT5H	P24941	CDK2	T859	P865H	865	Missense	distal	6	no	14.122	14.117	EPSD	ICGC;COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	O00267	SUPT5H	P24941	CDK2	T859	P857H	857	Missense	proximal	-2	no	14.122	13.112	EPSD	ICGC;COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	O00267	SUPT5H	P24941	CDK2	S866	S867P	867	Missense	proximal	1	no	2.448	13.714	EPSD	ICGC;COSMIC	8.148	Gain
CMGC_CDK_CDK2_CDK2_ST	O00267	SUPT5H	P24941	CDK2	S867	S867P	867	Missense	central	0	yes	15.527	0.000	EPSD	ICGC;COSMIC	8.148	Loss
CMGC_CDK_CDK2_CDK2_ST	O00267	SUPT5H	P24941	CDK2	S867	P865H	865	Missense	proximal	-2	no	15.527	14.517	EPSD	ICGC;COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	O00267	SUPT5H	P24941	CDK2	T878	T881M	881	Missense	distal	3	no	11.338	11.213	EPSD	ICGC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	O00267	SUPT5H	P24941	CDK2	T878	G880W	880	Missense	proximal	2	no	11.338	11.477	EPSD	ICGC;COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	O00267	SUPT5H	P24941	CDK2	T878	P876S	876	Missense	proximal	-2	no	11.338	10.687	EPSD	ICGC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	O00267	SUPT5H	P24941	CDK2	T881	T881M	881	Missense	central	0	yes	14.252	0.000	EPSD	ICGC	8.148	Loss
CMGC_CDK_CDK2_CDK2_ST	O00267	SUPT5H	P24941	CDK2	T881	G880W	880	Missense	proximal	-1	no	14.252	14.328	EPSD	ICGC;COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	O00267	SUPT5H	P24941	CDK2	T881	P876S	876	Missense	distal	-5	no	14.252	14.208	EPSD	ICGC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	O00267	SUPT5H	P24941	CDK2	S897	P904A	904	Missense	distal	7	no	12.335	12.720	EPSD	ICGC;COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	O00267	SUPT5H	P24941	CDK2	S897	P898T	898	Missense	proximal	1	no	12.335	2.378	EPSD	ICGC;COSMIC	8.148	Loss
CMGC_CDK_CDK2_CDK2_ST	O00267	SUPT5H	P24941	CDK2	S951	M953V	953	Missense	proximal	2	no	14.085	13.996	EPSD	ICGC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	O00267	SUPT5H	P24941	CDK2	S951	S946G	946	Missense	distal	-5	no	14.085	14.209	EPSD	ICGC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	O00267	SUPT5H	P24941	CDK2	T954	M953V	953	Missense	proximal	-1	no	15.122	14.029	EPSD	ICGC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	O00267	SUPT5H	P24941	CDK2	S959	M953V	953	Missense	distal	-6	no	14.507	14.501	EPSD	ICGC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	O00267	SUPT5H	P24941	CDK2	T967	P968S	968	Missense	proximal	1	no	13.793	2.527	EPSD	ICGC;GDSC;CCLE	8.148	Loss
CMGC_CDK_CDK2_CDK2_ST	O00267	SUPT5H	P24941	CDK2	S970	P968S	968	Missense	proximal	-2	no	8.711	8.059	EPSD	ICGC;GDSC;CCLE	8.148	Loss
CMGC_CDK_CDK2_CDK2_ST	O00267	SUPT5H	P24941	CDK2	T1034	P1035H	1035	Missense	proximal	1	no	15.546	8.787	EPSD	ICGC;COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	O00267	SUPT5H	P24941	CDK2	T1034	P1035T	1035	Missense	proximal	1	no	15.546	5.588	EPSD	ICGC;COSMIC	8.148	Loss
CMGC_CDK_CDK2_CDK2_ST	Q9UQR0	SCML2	P24941	CDK2	T20	Q22K	22	Missense	proximal	2	no	13.411	13.211	EPSD	ICGC;COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	Q9UQR0	SCML2	P24941	CDK2	S256	N249I	249	Missense	distal	-7	no	13.781	14.057	EPSD	ICGC;COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	Q9UQR0	SCML2	P24941	CDK2	S267	S267F	267	Missense	central	0	yes	13.843	0.000	EPSD	ICGC	8.148	Loss
CMGC_CDK_CDK2_CDK2_ST	Q9UQR0	SCML2	P24941	CDK2	S499	R498Q	498	Missense	proximal	-1	no	14.383	13.505	EPSD	ICGC;COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	Q9UQR0	SCML2	P24941	CDK2	S511	P512H	512	Missense	proximal	1	no	13.957	7.198	EPSD;PhosphoSitePlus	ICGC	8.148	Loss
CMGC_CDK_CDK2_CDK2_ST	Q9UQR0	SCML2	P24941	CDK2	S511	L510I	510	Missense	proximal	-1	no	13.957	14.119	EPSD;PhosphoSitePlus	ICGC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	Q9UQR0	SCML2	P24941	CDK2	S511	P512S	512	Missense	proximal	1	no	13.957	2.691	EPSD;PhosphoSitePlus	ICGC	8.148	Loss
CMGC_CDK_CDK2_CDK2_ST	Q9UQR0	SCML2	P24941	CDK2	S583	L585I	585	Missense	proximal	2	no	14.962	15.045	EPSD	ICGC;COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	Q9UQR0	SCML2	P24941	CDK2	S583	G587W	587	Missense	distal	4	no	14.962	14.601	EPSD	ICGC;COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	Q9UQR0	SCML2	P24941	CDK2	S583	G587V	587	Missense	distal	4	no	14.962	15.308	EPSD	ICGC;COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	Q9UQR0	SCML2	P24941	CDK2	S583	D588Y	588	Missense	distal	5	no	14.962	14.861	EPSD	ICGC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	Q9UQR0	SCML2	P24941	CDK2	S590	L585I	585	Missense	distal	-5	no	11.413	11.440	EPSD;PhosphoSitePlus	ICGC;COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	Q9UQR0	SCML2	P24941	CDK2	S590	P595T	595	Missense	distal	5	no	11.413	11.387	EPSD;PhosphoSitePlus	ICGC;COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	Q9UQR0	SCML2	P24941	CDK2	S590	G587W	587	Missense	distal	-3	no	11.413	11.579	EPSD;PhosphoSitePlus	ICGC;COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	Q9UQR0	SCML2	P24941	CDK2	S590	G587V	587	Missense	distal	-3	no	11.413	11.452	EPSD;PhosphoSitePlus	ICGC;COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	Q9UQR0	SCML2	P24941	CDK2	S590	D588Y	588	Missense	proximal	-2	no	11.413	10.983	EPSD;PhosphoSitePlus	ICGC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	Q9UQR0	SCML2	P24941	CDK2	S594	P595T	595	Missense	proximal	1	no	14.045	4.087	EPSD	ICGC;COSMIC	8.148	Loss
CMGC_CDK_CDK2_CDK2_ST	Q9UQR0	SCML2	P24941	CDK2	S594	G587W	587	Missense	distal	-7	no	14.045	14.235	EPSD	ICGC;COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	Q9UQR0	SCML2	P24941	CDK2	S594	G587V	587	Missense	distal	-7	no	14.045	13.740	EPSD	ICGC;COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	Q9UQR0	SCML2	P24941	CDK2	S594	D588Y	588	Missense	distal	-6	no	14.045	14.046	EPSD	ICGC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	P10275	AR	P24941	CDK2	S96	E93K	93	Missense	distal	-3	no	13.938	13.723	PhosphoSitePlus	ICGC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	P10275	AR	P24941	CDK2	S258	G260V	260	Missense	proximal	2	no	13.449	13.454	EPSD	ICGC;COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	P10275	AR	P24941	CDK2	T282	A288T	288	Missense	distal	6	no	10.776	10.788	EPSD	ICGC;COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	P10275	AR	P24941	CDK2	T282	R280L	280	Missense	proximal	-2	no	10.776	11.787	EPSD	ICGC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	P10275	AR	P24941	CDK2	T282	A288D	288	Missense	distal	6	no	10.776	10.765	EPSD	ICGC;COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	P10275	AR	P24941	CDK2	S310	T317A	317	Missense	distal	7	no	17.226	17.915	EPSD	ICGC;COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	P10275	AR	P24941	CDK2	S310	T303S	303	Missense	distal	-7	no	17.226	17.049	EPSD	ICGC;COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	P10275	AR	P24941	CDK2	S516	Y514H	514	Missense	proximal	-2	no	9.037	8.592	EPSD	ICGC;GDSC;CCLE	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	P10275	AR	P24941	CDK2	S516	S516I	516	Missense	central	0	yes	9.037	0.000	EPSD	ICGC	8.148	Loss
CMGC_CDK_CDK2_CDK2_ST	P10275	AR	P24941	CDK2	S516	V509L	509	Missense	distal	-7	no	9.037	9.023	EPSD	ICGC;COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	P10275	AR	P24941	CDK2	S792	C785F	785	Missense	distal	-7	no	8.373	8.473	EPSD	ICGC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	P10275	AR	P24941	CDK2	S792	R789S	789	Missense	distal	-3	no	8.373	8.279	EPSD	ICGC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	O43395	PRPF3	P24941	CDK2	S106	R112L	112	Missense	distal	6	no	8.829	8.847	EPSD	ICGC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	O43395	PRPF3	P24941	CDK2	S106	R112Q	112	Missense	distal	6	no	8.829	8.851	EPSD	ICGC;COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	P50750	CDK9	P24941	CDK2	S90	R94C	94	Missense	distal	4	no	14.155	13.528	PhosphoSitePlus	ICGC;COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	P50750	CDK9	P24941	CDK2	S90	R86L	86	Missense	distal	-4	no	14.155	14.340	PhosphoSitePlus	ICGC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	P50750	CDK9	P24941	CDK2	S90	C95F	95	Missense	distal	5	no	14.155	14.139	PhosphoSitePlus	ICGC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	P50750	CDK9	P24941	CDK2	S90	R94H	94	Missense	distal	4	no	14.155	14.038	PhosphoSitePlus	ICGC;COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	P50750	CDK9	P24941	CDK2	S175	P182S	182	Missense	distal	7	no	8.210	8.058	EPSD	ICGC;COSMIC	8.148	Loss
CMGC_CDK_CDK2_CDK2_ST	P50750	CDK9	P24941	CDK2	S175	F168Y	168	Missense	distal	-7	no	8.210	7.965	EPSD	ICGC	8.148	Loss
CMGC_CDK_CDK2_CDK2_ST	P50750	CDK9	P24941	CDK2	S180	N183K	183	Missense	distal	3	no	6.681	9.951	EPSD	ICGC;COSMIC	8.148	Gain
CMGC_CDK_CDK2_CDK2_ST	P50750	CDK9	P24941	CDK2	S347	Q351H	351	Missense	distal	4	no	8.180	7.881	EPSD	ICGC;COSMIC	8.148	Loss
CMGC_CDK_CDK2_CDK2_ST	P50750	CDK9	P24941	CDK2	S347	Q348H	348	Missense	proximal	1	no	8.180	9.333	EPSD	ICGC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	Q9Y676	MRPS18B	P24941	CDK2	S49	S42Y	42	Missense	distal	-7	no	18.412	18.718	PhosphoSitePlus	ICGC;COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	P46527	CDKN1B	P24941	CDK2	S10	N8K	8	Missense	proximal	-2	no	12.148	12.977	EPSD	ICGC;COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	P46527	CDKN1B	P24941	CDK2	S110	V109G	109	Missense	proximal	-1	no	9.560	10.652	EPSD	ICGC;COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	P46527	CDKN1B	P24941	CDK2	S178	V184M	184	Missense	distal	6	no	15.197	15.179	EPSD	ICGC;COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	P46527	CDKN1B	P24941	CDK2	S178	G182C	182	Missense	distal	4	no	15.197	14.569	EPSD	ICGC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	P46527	CDKN1B	P24941	CDK2	S178	G177V	177	Missense	proximal	-1	no	15.197	14.105	EPSD	ICGC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	P46527	CDKN1B	P24941	CDK2	S178	S178F	178	Missense	central	0	yes	15.197	0.000	EPSD	ICGC;COSMIC	8.148	Loss
CMGC_CDK_CDK2_CDK2_ST	P46527	CDKN1B	P24941	CDK2	T187	V184M	184	Missense	distal	-3	no	16.370	16.595	EPSD;PhosphoSitePlus	ICGC;COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	P46527	CDKN1B	P24941	CDK2	T187	G192V	192	Missense	distal	5	no	16.370	16.210	EPSD;PhosphoSitePlus	ICGC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	P46527	CDKN1B	P24941	CDK2	T187	G182C	182	Missense	distal	-5	no	16.370	16.371	EPSD;PhosphoSitePlus	ICGC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	P46527	CDKN1B	P24941	CDK2	T187	P191H	191	Missense	distal	4	no	16.370	16.132	EPSD;PhosphoSitePlus	ICGC;COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	Q13415	ORC1	P24941	CDK2	T224	P225T	225	Missense	proximal	1	no	11.701	1.744	EPSD	ICGC	8.148	Loss
CMGC_CDK_CDK2_CDK2_ST	Q13415	ORC1	P24941	CDK2	T230	A233D	233	Missense	distal	3	no	15.215	13.913	EPSD	ICGC;COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	Q13415	ORC1	P24941	CDK2	T230	P225T	225	Missense	distal	-5	no	15.215	15.213	EPSD	ICGC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	Q13415	ORC1	P24941	CDK2	S258	C253S	253	Missense	distal	-5	no	15.023	14.898	EPSD;PhosphoSitePlus	ICGC;COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	Q13415	ORC1	P24941	CDK2	S273	E270K	270	Missense	distal	-3	no	16.209	15.994	PhosphoSitePlus;EPSD	ICGC;COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	Q13415	ORC1	P24941	CDK2	S273	K276N	276	Missense	distal	3	no	16.209	12.939	PhosphoSitePlus;EPSD	ICGC;COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	Q13415	ORC1	P24941	CDK2	S273	S278T	278	Missense	distal	5	no	16.209	16.284	PhosphoSitePlus;EPSD	ICGC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	Q13415	ORC1	P24941	CDK2	S287	P293L	293	Missense	distal	6	no	14.037	14.038	EPSD	ICGC;COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	Q13415	ORC1	P24941	CDK2	S287	L283R	283	Missense	distal	-4	no	14.037	13.852	EPSD	ICGC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	Q13415	ORC1	P24941	CDK2	S311	K308N	308	Missense	distal	-3	no	14.749	14.811	EPSD	ICGC;COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	Q13415	ORC1	P24941	CDK2	S311	D307E	307	Missense	distal	-4	no	14.749	14.453	EPSD	ICGC;COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	Q13415	ORC1	P24941	CDK2	S311	I317M	317	Missense	distal	6	no	14.749	14.730	EPSD	ICGC;COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	Q13415	ORC1	P24941	CDK2	S311	T304I	304	Missense	distal	-7	no	14.749	14.946	EPSD	ICGC;COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	Q13415	ORC1	P24941	CDK2	T428	P429A	429	Missense	proximal	1	no	14.917	0.513	EPSD	ICGC;COSMIC	8.148	Loss
CMGC_CDK_CDK2_CDK2_ST	Q13415	ORC1	P24941	CDK2	T428	P430T	430	Missense	proximal	2	no	14.917	14.739	EPSD	ICGC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	Q13415	ORC1	P24941	CDK2	T428	D422G	422	Missense	distal	-6	no	14.917	14.921	EPSD	ICGC;COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	Q13415	ORC1	P24941	CDK2	T428	R433S	433	Missense	distal	5	no	14.917	14.710	EPSD	ICGC;COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	Q13415	ORC1	P24941	CDK2	S610	P611S	611	Missense	proximal	1	no	16.736	5.470	EPSD	ICGC;COSMIC	8.148	Loss
CMGC_CDK_CDK2_CDK2_ST	Q13415	ORC1	P24941	CDK2	S610	R608L	608	Missense	proximal	-2	no	16.736	17.747	EPSD	ICGC;COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	Q13415	ORC1	P24941	CDK2	S610	V616I	616	Missense	distal	6	no	16.736	16.737	EPSD	ICGC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	P54132	BLM	P24941	CDK2	T57	T50S	50	Missense	distal	-7	no	14.943	14.765	EPSD	ICGC;COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	P54132	BLM	P24941	CDK2	S144	S147Y	147	Missense	distal	3	no	15.323	14.543	EPSD	ICGC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	P54132	BLM	P24941	CDK2	S282	V286F	286	Missense	distal	4	no	9.693	9.284	EPSD	ICGC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	P54132	BLM	P24941	CDK2	S304	T298M	298	Missense	distal	-6	no	12.972	12.979	EPSD	ICGC;COSMIC;GDSC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	P54132	BLM	P24941	CDK2	S304	S304Y	304	Missense	central	0	yes	12.972	0.000	EPSD	ICGC	8.148	Loss
CMGC_CDK_CDK2_CDK2_ST	P54132	BLM	P24941	CDK2	S328	V334F	334	Missense	distal	6	no	9.400	9.384	EPSD	ICGC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	P54132	BLM	P24941	CDK2	S328	V334I	334	Missense	distal	6	no	9.400	9.402	EPSD	ICGC;COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	P54132	BLM	P24941	CDK2	S456	N454T	454	Missense	proximal	-2	no	7.453	8.763	EPSD	ICGC	8.148	Gain
CMGC_CDK_CDK2_CDK2_ST	P54132	BLM	P24941	CDK2	T508	W505L	505	Missense	distal	-3	no	11.924	11.584	EPSD	ICGC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	P54132	BLM	P24941	CDK2	S706	A703V	703	Missense	distal	-3	no	14.649	14.850	EPSD	ICGC;COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	P54132	BLM	P24941	CDK2	S706	V705I	705	Missense	proximal	-1	no	14.649	14.675	EPSD	ICGC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	P54132	BLM	P24941	CDK2	S706	V705F	705	Missense	proximal	-1	no	14.649	15.478	EPSD	ICGC;COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	P54132	BLM	P24941	CDK2	S706	C704F	704	Missense	proximal	-2	no	14.649	14.598	EPSD	ICGC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	P54132	BLM	P24941	CDK2	S706	T710N	710	Missense	distal	4	no	14.649	14.346	EPSD	ICGC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	P54132	BLM	P24941	CDK2	S706	S706Y	706	Missense	central	0	yes	14.649	0.000	EPSD	ICGC	8.148	Loss
CMGC_CDK_CDK2_CDK2_ST	P54132	BLM	P24941	CDK2	S706	P707S	707	Missense	proximal	1	no	14.649	3.383	EPSD	ICGC;COSMIC;GDSC	8.148	Loss
CMGC_CDK_CDK2_CDK2_ST	P54132	BLM	P24941	CDK2	S714	V721L	721	Missense	distal	7	no	14.707	14.479	EPSD	ICGC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	P54132	BLM	P24941	CDK2	S714	T710N	710	Missense	distal	-4	no	14.707	14.679	EPSD	ICGC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	P54132	BLM	P24941	CDK2	S714	P707S	707	Missense	distal	-7	no	14.707	14.527	EPSD	ICGC;COSMIC;GDSC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	P54132	BLM	P24941	CDK2	T766	Y764C	764	Missense	proximal	-2	no	16.368	15.871	EPSD	ICGC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	P54132	BLM	P24941	CDK2	T907	Q909H	909	Missense	proximal	2	no	9.347	9.365	EPSD	ICGC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	P54132	BLM	P24941	CDK2	T907	Q909R	909	Missense	proximal	2	no	9.347	9.446	EPSD	ICGC;COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	P54132	BLM	P24941	CDK2	T907	T907M	907	Missense	central	0	yes	9.347	0.000	EPSD	ICGC;COSMIC	8.148	Loss
CMGC_CDK_CDK2_CDK2_ST	P54132	BLM	P24941	CDK2	S1290	P1297Q	1297	Missense	distal	7	no	14.154	13.999	EPSD	ICGC;COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	P54132	BLM	P24941	CDK2	S1296	P1297Q	1297	Missense	proximal	1	no	13.185	5.273	EPSD	ICGC;COSMIC	8.148	Loss
CMGC_CDK_CDK2_CDK2_ST	O00429	DNM1L	P24941	CDK2	S126	K123N	123	Missense	distal	-3	no	13.109	13.171	EPSD	ICGC;COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	O00429	DNM1L	P24941	CDK2	S548	A541S	541	Missense	distal	-7	no	14.167	13.823	EPSD	ICGC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	O00429	DNM1L	P24941	CDK2	S548	S548F	548	Missense	central	0	yes	14.167	0.000	EPSD	ICGC;COSMIC	8.148	Loss
CMGC_CDK_CDK2_CDK2_ST	O00429	DNM1L	P24941	CDK2	S548	A553T	553	Missense	distal	5	no	14.167	14.131	EPSD	ICGC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	O00429	DNM1L	P24941	CDK2	S548	A553V	553	Missense	distal	5	no	14.167	14.124	EPSD	ICGC;COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	O00429	DNM1L	P24941	CDK2	S548	S548Y	548	Missense	central	0	yes	14.167	0.000	EPSD	ICGC;COSMIC	8.148	Loss
CMGC_CDK_CDK2_CDK2_ST	Q8IXM2	C17orf49	P24941	CDK2	S36	A38E	38	Missense	proximal	2	no	12.637	12.709	EPSD	ICGC;COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	Q8IXM2	C17orf49	P24941	CDK2	S36	S36Y	36	Missense	central	0	yes	12.637	0.000	EPSD	ICGC;COSMIC	8.148	Loss
CMGC_CDK_CDK2_CDK2_ST	Q8IXM2	C17orf49	P24941	CDK2	S36	D34G	34	Missense	proximal	-2	no	12.637	12.029	EPSD	ICGC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	Q8IXM2	C17orf49	P24941	CDK2	S110	S110L	110	Missense	central	0	yes	12.905	0.000	EPSD	ICGC;COSMIC	8.148	Loss
CMGC_CDK_CDK2_CDK2_ST	Q8IXM2	C17orf49	P24941	CDK2	S110	A115D	115	Missense	distal	5	no	12.905	13.069	EPSD	ICGC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	Q8IXM2	C17orf49	P24941	CDK2	S110	A114V	114	Missense	distal	4	no	12.905	13.092	EPSD	ICGC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	P28749	RBL1	P24941	CDK2	T332	D325E	325	Missense	distal	-7	no	18.255	18.104	EPSD	ICGC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	P28749	RBL1	P24941	CDK2	T385	A388E	388	Missense	distal	3	no	12.535	13.669	EPSD	ICGC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	P28749	RBL1	P24941	CDK2	S615	P613S	613	Missense	proximal	-2	no	17.319	16.668	EPSD	ICGC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	P28749	RBL1	P24941	CDK2	S615	P613Q	613	Missense	proximal	-2	no	17.319	16.752	EPSD	ICGC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	P28749	RBL1	P24941	CDK2	S615	M614I	614	Missense	proximal	-1	no	17.319	16.253	EPSD	ICGC;COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	P28749	RBL1	P24941	CDK2	S749	E744G	744	Missense	distal	-5	no	13.135	13.177	EPSD	ICGC;COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	P28749	RBL1	P24941	CDK2	S762	N767S	767	Missense	distal	5	no	13.711	13.507	EPSD	ICGC;COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	P28749	RBL1	P24941	CDK2	T915	C918F	918	Missense	distal	3	no	7.835	12.440	EPSD	ICGC;COSMIC	8.148	Gain
CMGC_CDK_CDK2_CDK2_ST	P28749	RBL1	P24941	CDK2	S964	P967Q	967	Missense	distal	3	no	14.832	14.807	EPSD	ICGC;COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	P28749	RBL1	P24941	CDK2	S964	L963I	963	Missense	proximal	-1	no	14.832	14.994	EPSD	ICGC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	P28749	RBL1	P24941	CDK2	S964	P961L	961	Missense	distal	-3	no	14.832	14.761	EPSD	ICGC;COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	P28749	RBL1	P24941	CDK2	S975	S975L	975	Missense	central	0	yes	15.212	0.000	EPSD	ICGC;COSMIC	8.148	Loss
CMGC_CDK_CDK2_CDK2_ST	P28749	RBL1	P24941	CDK2	S975	R977H	977	Missense	proximal	2	no	15.212	15.131	EPSD	ICGC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	P28749	RBL1	P24941	CDK2	S988	G995V	995	Missense	distal	7	no	16.752	16.340	EPSD	ICGC;COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	P28749	RBL1	P24941	CDK2	S988	P989Q	989	Missense	proximal	1	no	16.752	8.840	EPSD	ICGC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	P28749	RBL1	P24941	CDK2	T997	L1002V	1002	Missense	distal	5	no	15.469	15.396	EPSD	ICGC;COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	P28749	RBL1	P24941	CDK2	T997	G995V	995	Missense	proximal	-2	no	15.469	15.562	EPSD	ICGC;COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	P28749	RBL1	P24941	CDK2	T997	A1001D	1001	Missense	distal	4	no	15.469	15.364	EPSD	ICGC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	P28749	RBL1	P24941	CDK2	T997	S1000R	1000	Missense	distal	3	no	15.469	17.153	EPSD	ICGC;COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	P28749	RBL1	P24941	CDK2	S1009	L1002V	1002	Missense	distal	-7	no	17.199	17.213	EPSD	ICGC;COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	P28749	RBL1	P24941	CDK2	S1009	S1009R	1009	Missense	central	0	yes	17.199	0.000	EPSD	ICGC	8.148	Loss
CMGC_CDK_CDK2_CDK2_ST	P28749	RBL1	P24941	CDK2	S1009	K1012E	1012	Missense	distal	3	no	17.199	15.113	EPSD	ICGC;COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	P28749	RBL1	P24941	CDK2	S1041	R1045H	1045	Missense	distal	4	no	16.162	16.044	EPSD	ICGC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	P28749	RBL1	P24941	CDK2	S1041	A1034D	1034	Missense	distal	-7	no	16.162	16.238	EPSD	ICGC;COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	P28749	RBL1	P24941	CDK2	S1041	I1035V	1035	Missense	distal	-6	no	16.162	16.161	EPSD	ICGC;COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	P28749	RBL1	P24941	CDK2	S1041	C1047F	1047	Missense	distal	6	no	16.162	16.157	EPSD	ICGC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	P13051	UNG	P24941	CDK2	S12	L7F	7	Missense	distal	-5	no	13.559	13.619	PhosphoSitePlus;EPSD	ICGC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	P13051	UNG	P24941	CDK2	S14	L7F	7	Missense	distal	-7	no	14.457	14.822	EPSD	ICGC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	P13051	UNG	P24941	CDK2	T60	P62H	62	Missense	proximal	2	no	14.936	15.014	EPSD;PhosphoSitePlus	ICGC;COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	P13051	UNG	P24941	CDK2	T60	P65L	65	Missense	distal	5	no	14.936	14.976	EPSD;PhosphoSitePlus	ICGC;COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	P13051	UNG	P24941	CDK2	S64	P62H	62	Missense	proximal	-2	no	12.611	11.601	EPSD;PhosphoSitePlus	ICGC;COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	P13051	UNG	P24941	CDK2	S64	P65L	65	Missense	proximal	1	no	12.611	2.790	EPSD;PhosphoSitePlus	ICGC;COSMIC	8.148	Loss
CMGC_CDK_CDK2_CDK2_ST	Q92547	TOPBP1	P24941	CDK2	T298	N304K	304	Missense	distal	6	no	13.774	13.779	EPSD	ICGC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	Q92547	TOPBP1	P24941	CDK2	T298	T300N	300	Missense	proximal	2	no	13.774	13.881	EPSD	ICGC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	Q92547	TOPBP1	P24941	CDK2	T298	P299H	299	Missense	proximal	1	no	13.774	7.016	EPSD	ICGC	8.148	Loss
CMGC_CDK_CDK2_CDK2_ST	Q92547	TOPBP1	P24941	CDK2	S301	N304K	304	Missense	distal	3	no	6.666	9.936	EPSD	ICGC	8.148	Gain
CMGC_CDK_CDK2_CDK2_ST	Q92547	TOPBP1	P24941	CDK2	S370	R372K	372	Missense	proximal	2	no	10.388	10.088	EPSD	ICGC;COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	Q92547	TOPBP1	P24941	CDK2	S370	L374I	374	Missense	distal	4	no	10.388	10.247	EPSD	ICGC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	Q92547	TOPBP1	P24941	CDK2	S370	S370C	370	Missense	central	0	yes	10.388	0.000	EPSD	ICGC;COSMIC	8.148	Loss
CMGC_CDK_CDK2_CDK2_ST	Q92547	TOPBP1	P24941	CDK2	S498	S499P	499	Missense	proximal	1	no	3.299	14.565	EPSD	ICGC	8.148	Gain
CMGC_CDK_CDK2_CDK2_ST	Q92547	TOPBP1	P24941	CDK2	T779	R785S	785	Missense	distal	6	no	11.270	11.287	EPSD	ICGC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	Q92547	TOPBP1	P24941	CDK2	S805	Q810K	810	Missense	distal	5	no	14.896	14.882	EPSD	ICGC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	Q92547	TOPBP1	P24941	CDK2	S805	A803T	803	Missense	proximal	-2	no	14.896	14.846	EPSD	ICGC;COSMIC;GDSC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	Q92547	TOPBP1	P24941	CDK2	T822	S817L	817	Missense	distal	-5	no	17.224	17.280	EPSD	ICGC;COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	Q92547	TOPBP1	P24941	CDK2	T822	K829N	829	Missense	distal	7	no	17.224	17.417	EPSD	ICGC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	Q92547	TOPBP1	P24941	CDK2	T848	P849S	849	Missense	proximal	1	no	15.210	3.944	PhosphoSitePlus	ICGC	8.148	Loss
CMGC_CDK_CDK2_CDK2_ST	Q92547	TOPBP1	P24941	CDK2	S853	P849S	849	Missense	distal	-4	no	8.475	8.829	EPSD	ICGC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	Q92547	TOPBP1	P24941	CDK2	S853	S860N	860	Missense	distal	7	no	8.475	8.533	EPSD	ICGC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	Q92547	TOPBP1	P24941	CDK2	T861	V868I	868	Missense	distal	7	no	11.412	11.211	EPSD	ICGC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	Q92547	TOPBP1	P24941	CDK2	T861	S860N	860	Missense	proximal	-1	no	11.412	11.810	EPSD	ICGC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	Q92547	TOPBP1	P24941	CDK2	T861	I867M	867	Missense	distal	6	no	11.412	11.393	EPSD	ICGC;COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	Q92547	TOPBP1	P24941	CDK2	S888	S888R	888	Missense	central	0	yes	12.388	0.000	EPSD	ICGC;COSMIC	8.148	Loss
CMGC_CDK_CDK2_CDK2_ST	Q92547	TOPBP1	P24941	CDK2	S888	A882D	882	Missense	distal	-6	no	12.388	12.387	EPSD	ICGC;COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	Q92547	TOPBP1	P24941	CDK2	S1183	P1188S	1188	Missense	distal	5	no	13.212	13.111	EPSD	ICGC;COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	Q92547	TOPBP1	P24941	CDK2	S1183	Q1186K	1186	Missense	distal	3	no	13.212	15.944	EPSD	ICGC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	Q92547	TOPBP1	P24941	CDK2	T1221	D1225Y	1225	Missense	distal	4	no	17.366	17.630	EPSD	ICGC;COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	Q92547	TOPBP1	P24941	CDK2	T1221	S1216Y	1216	Missense	distal	-5	no	17.366	17.434	EPSD	ICGC;COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	Q92547	TOPBP1	P24941	CDK2	T1221	D1225E	1225	Missense	distal	4	no	17.366	17.447	EPSD	ICGC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	Q92547	TOPBP1	P24941	CDK2	T1221	S1226R	1226	Missense	distal	5	no	17.366	17.573	EPSD	ICGC;COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	Q92547	TOPBP1	P24941	CDK2	T1231	T1231M	1231	Missense	central	0	yes	13.097	0.000	EPSD	ICGC;COSMIC	8.148	Loss
CMGC_CDK_CDK2_CDK2_ST	Q92547	TOPBP1	P24941	CDK2	T1231	D1225Y	1225	Missense	distal	-6	no	13.097	13.099	EPSD	ICGC;COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	Q92547	TOPBP1	P24941	CDK2	T1231	D1225E	1225	Missense	distal	-6	no	13.097	13.101	EPSD	ICGC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	Q92547	TOPBP1	P24941	CDK2	T1231	S1226R	1226	Missense	distal	-5	no	13.097	13.188	EPSD	ICGC;COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	Q92785	DPF2	P24941	CDK2	S142	E145K	145	Missense	distal	3	no	6.552	8.637	EPSD	ICGC;COSMIC	8.148	Gain
CMGC_CDK_CDK2_CDK2_ST	Q92785	DPF2	P24941	CDK2	T176	K178N	178	Missense	proximal	2	no	16.849	16.920	PhosphoSitePlus	ICGC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	Q92785	DPF2	P24941	CDK2	T248	P249H	249	Missense	proximal	1	no	15.200	8.442	EPSD	ICGC;COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	Q92785	DPF2	P24941	CDK2	T310	H303Y	303	Missense	distal	-7	no	12.339	12.342	EPSD	ICGC;COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	Q92785	DPF2	P24941	CDK2	T310	M314I	314	Missense	distal	4	no	12.339	12.732	EPSD	ICGC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	Q9UEY8	ADD3	P24941	CDK2	T12	M18I	18	Missense	distal	6	no	13.195	13.214	EPSD	ICGC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	Q9UEY8	ADD3	P24941	CDK2	T12	S6R	6	Missense	distal	-6	no	13.195	13.198	EPSD	ICGC;COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	Q9UEY8	ADD3	P24941	CDK2	T12	P15S	15	Missense	distal	3	no	13.195	13.229	EPSD	ICGC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	Q9UEY8	ADD3	P24941	CDK2	S42	M41I	41	Missense	proximal	-1	no	14.917	13.850	EPSD	ICGC;COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	Q9UEY8	ADD3	P24941	CDK2	S64	R57Q	57	Missense	distal	-7	no	13.449	13.062	EPSD	ICGC;COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	Q9UEY8	ADD3	P24941	CDK2	S64	Q60K	60	Missense	distal	-4	no	13.449	13.586	EPSD	ICGC;COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	Q9UEY8	ADD3	P24941	CDK2	S108	P109H	109	Missense	proximal	1	no	11.625	4.866	EPSD	ICGC;COSMIC	8.148	Loss
CMGC_CDK_CDK2_CDK2_ST	Q9UEY8	ADD3	P24941	CDK2	S108	S108L	108	Missense	central	0	yes	11.625	0.000	EPSD	ICGC;COSMIC	8.148	Loss
CMGC_CDK_CDK2_CDK2_ST	Q9UEY8	ADD3	P24941	CDK2	S108	G105C	105	Missense	distal	-3	no	11.625	11.624	EPSD	ICGC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	Q9UEY8	ADD3	P24941	CDK2	S108	G114V	114	Missense	distal	6	no	11.625	11.634	EPSD	ICGC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	Q9UEY8	ADD3	P24941	CDK2	T117	I119V	119	Missense	proximal	2	no	13.273	13.418	EPSD	ICGC;COSMIC;GDSC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	Q9UEY8	ADD3	P24941	CDK2	T117	G124C	124	Missense	distal	7	no	13.273	13.244	EPSD	ICGC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	Q9UEY8	ADD3	P24941	CDK2	T117	G114V	114	Missense	distal	-3	no	13.273	13.312	EPSD	ICGC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	Q9UEY8	ADD3	P24941	CDK2	S360	V366F	366	Missense	distal	6	no	11.189	11.173	EPSD	ICGC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	Q9UEY8	ADD3	P24941	CDK2	S360	K363N	363	Missense	distal	3	no	11.189	7.919	EPSD	ICGC;COSMIC	8.148	Loss
CMGC_CDK_CDK2_CDK2_ST	Q9UEY8	ADD3	P24941	CDK2	S423	D417E	417	Missense	distal	-6	no	17.772	17.776	PhosphoSitePlus	ICGC;COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	Q9UEY8	ADD3	P24941	CDK2	S442	V449M	449	Missense	distal	7	no	15.579	15.866	EPSD	ICGC;COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	Q9UEY8	ADD3	P24941	CDK2	S442	N441S	441	Missense	proximal	-1	no	15.579	15.182	EPSD	ICGC;COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	Q9UEY8	ADD3	P24941	CDK2	T481	P488Q	488	Missense	distal	7	no	15.493	15.339	EPSD	ICGC;COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	Q9UEY8	ADD3	P24941	CDK2	S600	S600P	600	Missense	central	0	yes	12.579	0.000	EPSD	ICGC;COSMIC	8.148	Loss
CMGC_CDK_CDK2_CDK2_ST	Q9UEY8	ADD3	P24941	CDK2	S664	K663N	663	Missense	proximal	-1	no	14.352	14.379	EPSD	ICGC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	Q9UEY8	ADD3	P24941	CDK2	T691	R690S	690	Missense	proximal	-1	no	14.131	13.089	EPSD	ICGC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	Q0VD86	INCA1	P24941	CDK2	S191	Q198K	198	Missense	distal	7	no	13.226	13.095	PhosphoSitePlus;EPSD	ICGC;COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	Q0VD86	INCA1	P24941	CDK2	S194	Q198K	198	Missense	distal	4	no	11.992	12.332	EPSD	ICGC;COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	P61978	HNRNPK	P24941	CDK2	S116	T118N	118	Missense	proximal	2	no	14.915	15.022	EPSD	ICGC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	P61978	HNRNPK	P24941	CDK2	S116	E110D	110	Missense	distal	-6	no	14.915	14.911	EPSD	ICGC;COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	P61978	HNRNPK	P24941	CDK2	S116	L123H	123	Missense	distal	7	no	14.915	15.016	EPSD	ICGC;COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	P61978	HNRNPK	P24941	CDK2	S214	I213M	213	Missense	proximal	-1	no	7.356	8.423	EPSD	ICGC	8.148	Gain
CMGC_CDK_CDK2_CDK2_ST	P61978	HNRNPK	P24941	CDK2	S216	D211H	211	Missense	distal	-5	no	19.794	19.783	EPSD;PhosphoSitePlus	ICGC;COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	P61978	HNRNPK	P24941	CDK2	S216	I213M	213	Missense	distal	-3	no	19.794	20.142	EPSD;PhosphoSitePlus	ICGC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	P61978	HNRNPK	P24941	CDK2	S302	A304T	304	Missense	proximal	2	no	8.160	7.958	EPSD	ICGC;COSMIC	8.148	Loss
CMGC_CDK_CDK2_CDK2_ST	P42677	RPS27	P24941	CDK2	S11	P10S	10	Missense	proximal	-1	no	11.693	11.222	EPSD	ICGC;COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	P42677	RPS27	P24941	CDK2	S11	L8I	8	Missense	distal	-3	no	11.693	11.784	EPSD	ICGC;COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	P42677	RPS27	P24941	CDK2	S27	K22R	22	Missense	distal	-5	no	15.410	15.454	PhosphoSitePlus	ICGC;COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	P42677	RPS27	P24941	CDK2	S27	S30Y	30	Missense	distal	3	no	15.410	14.630	PhosphoSitePlus	ICGC;COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	O00311	CDC7	P24941	CDK2	S16	E11D	11	Missense	distal	-5	no	15.438	15.458	EPSD	ICGC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	O00311	CDC7	P24941	CDK2	S16	P12S	12	Missense	distal	-4	no	15.438	15.792	EPSD	ICGC;COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	O00311	CDC7	P24941	CDK2	T472	D469V	469	Missense	distal	-3	no	12.177	12.255	EPSD	ICGC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	O00311	CDC7	P24941	CDK2	T503	V501I	501	Missense	proximal	-2	no	13.262	13.758	EPSD	ICGC;COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	O00311	CDC7	P24941	CDK2	T503	S498A	498	Missense	distal	-5	no	13.262	13.331	EPSD	ICGC;COSMIC;GDSC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	O00311	CDC7	P24941	CDK2	T503	G506V	506	Missense	distal	3	no	13.262	13.971	EPSD	ICGC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	P24941	CDK2	P24941	CDK2	T160	R157W	157	Missense	distal	-3	no	12.187	12.268	PhosphoSitePlus	ICGC;COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	P24941	CDK2	P24941	CDK2	T160	R157L	157	Missense	distal	-3	no	12.187	11.927	PhosphoSitePlus	ICGC;COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	Q14980	NUMA1	P24941	CDK2	S77	P78Q	78	Missense	proximal	1	no	10.824	2.912	EPSD	ICGC	8.148	Loss
CMGC_CDK_CDK2_CDK2_ST	Q14980	NUMA1	P24941	CDK2	S112	T107A	107	Missense	distal	-5	no	11.332	11.358	EPSD	ICGC;COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	Q14980	NUMA1	P24941	CDK2	S169	P165T	165	Missense	distal	-4	no	9.491	9.657	EPSD	ICGC;COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	Q14980	NUMA1	P24941	CDK2	S200	S200Y	200	Missense	central	0	yes	14.758	0.000	EPSD	ICGC	8.148	Loss
CMGC_CDK_CDK2_CDK2_ST	Q14980	NUMA1	P24941	CDK2	S200	G199S	199	Missense	proximal	-1	no	14.758	13.238	EPSD	ICGC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	Q14980	NUMA1	P24941	CDK2	S203	S200Y	200	Missense	distal	-3	no	14.035	14.054	EPSD	ICGC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	Q14980	NUMA1	P24941	CDK2	S203	Q210K	210	Missense	distal	7	no	14.035	13.903	EPSD	ICGC;COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	Q14980	NUMA1	P24941	CDK2	S203	G199S	199	Missense	distal	-4	no	14.035	14.707	EPSD	ICGC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	Q14980	NUMA1	P24941	CDK2	T211	R218Q	218	Missense	distal	7	no	14.360	13.715	EPSD	ICGC;COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	Q14980	NUMA1	P24941	CDK2	T211	Q210K	210	Missense	proximal	-1	no	14.360	14.567	EPSD	ICGC;COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	Q14980	NUMA1	P24941	CDK2	S271	P272T	272	Missense	proximal	1	no	13.707	3.750	EPSD	ICGC;GDSC;CCLE	8.148	Loss
CMGC_CDK_CDK2_CDK2_ST	Q14980	NUMA1	P24941	CDK2	S861	A857T	857	Missense	distal	-4	no	8.445	8.670	EPSD	ICGC;COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	Q15717	ELAVL1	P24941	CDK2	S221	A215V	215	Missense	distal	-6	no	13.732	13.735	EPSD	ICGC;COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	Q15717	ELAVL1	P24941	CDK2	S221	S221F	221	Missense	central	0	yes	13.732	0.000	EPSD	ICGC;COSMIC	8.148	Loss
CMGC_CDK_CDK2_CDK2_ST	Q15717	ELAVL1	P24941	CDK2	S221	G224C	224	Missense	distal	3	no	13.732	9.188	EPSD	ICGC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	Q15717	ELAVL1	P24941	CDK2	S221	F218L	218	Missense	distal	-3	no	13.732	13.475	EPSD	ICGC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	Q15717	ELAVL1	P24941	CDK2	S221	Q216R	216	Missense	distal	-5	no	13.732	13.779	EPSD	ICGC;COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	P24864	CCNE1	P24941	CDK2	S90	S90L	90	Missense	central	0	yes	8.750	0.000	EPSD	ICGC	8.148	Loss
CMGC_CDK_CDK2_CDK2_ST	P24864	CCNE1	P24941	CDK2	S103	P106H	106	Missense	distal	3	no	16.109	17.131	EPSD	ICGC;COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	P24864	CCNE1	P24941	CDK2	S103	V107A	107	Missense	distal	4	no	16.109	15.921	EPSD	ICGC;COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	P24864	CCNE1	P24941	CDK2	S387	L394I	394	Missense	distal	7	no	13.244	13.271	EPSD;PhosphoSitePlus	ICGC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	P24864	CCNE1	P24941	CDK2	T395	S399I	399	Missense	distal	4	no	13.881	13.839	PhosphoSitePlus;EPSD	ICGC;COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	P24864	CCNE1	P24941	CDK2	T395	S399R	399	Missense	distal	4	no	13.881	13.748	PhosphoSitePlus;EPSD	ICGC;COSMIC;GDSC;CCLE	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	P24864	CCNE1	P24941	CDK2	T395	G400D	400	Missense	distal	5	no	13.881	13.928	PhosphoSitePlus;EPSD	ICGC;COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	P24864	CCNE1	P24941	CDK2	T395	L394I	394	Missense	proximal	-1	no	13.881	14.043	PhosphoSitePlus;EPSD	ICGC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	P24864	CCNE1	P24941	CDK2	S399	G406W	406	Missense	distal	7	no	10.890	11.109	EPSD;PhosphoSitePlus	ICGC;COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	P24864	CCNE1	P24941	CDK2	S399	S399I	399	Missense	central	0	yes	10.890	0.000	EPSD;PhosphoSitePlus	ICGC;COSMIC	8.148	Loss
CMGC_CDK_CDK2_CDK2_ST	P24864	CCNE1	P24941	CDK2	S399	S399R	399	Missense	central	0	yes	10.890	0.000	EPSD;PhosphoSitePlus	ICGC;COSMIC;GDSC;CCLE	8.148	Loss
CMGC_CDK_CDK2_CDK2_ST	P24864	CCNE1	P24941	CDK2	S399	G400D	400	Missense	proximal	1	no	10.890	9.958	EPSD;PhosphoSitePlus	ICGC;COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	P24864	CCNE1	P24941	CDK2	S399	L394I	394	Missense	distal	-5	no	10.890	10.917	EPSD;PhosphoSitePlus	ICGC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	Q14103	HNRNPD	P24941	CDK2	S83	A90E	90	Missense	distal	7	no	14.213	13.873	EPSD	ICGC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	Q14103	HNRNPD	P24941	CDK2	S83	P84T	84	Missense	proximal	1	no	14.213	4.256	EPSD	ICGC;COSMIC	8.148	Loss
CMGC_CDK_CDK2_CDK2_ST	P31350	RRM2	P24941	CDK2	S20	Q15R	15	Missense	distal	-5	no	16.245	16.292	EPSD;PhosphoSitePlus	ICGC;COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	P31350	RRM2	P24941	CDK2	T33	G39W	39	Missense	distal	6	no	12.401	12.389	PhosphoSitePlus;EPSD	ICGC;COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	P31350	RRM2	P24941	CDK2	T56	R50S	50	Missense	distal	-6	no	8.630	8.628	EPSD	ICGC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	P31350	RRM2	P24941	CDK2	S377	S382Y	382	Missense	distal	5	no	12.856	13.031	EPSD	ICGC;COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	P31350	RRM2	P24941	CDK2	S377	M375V	375	Missense	proximal	-2	no	12.856	14.291	EPSD	ICGC;COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	P31350	RRM2	P24941	CDK2	S377	E380K	380	Missense	distal	3	no	12.856	14.942	EPSD	ICGC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	P31350	RRM2	P24941	CDK2	S377	T379A	379	Missense	proximal	2	no	12.856	13.058	EPSD	ICGC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	P31350	RRM2	P24941	CDK2	S377	E380D	380	Missense	distal	3	no	12.856	10.420	EPSD	ICGC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	P16949	STMN1	P24941	CDK2	S25	L24F	24	Missense	proximal	-1	no	14.872	15.837	PhosphoSitePlus;EPSD	ICGC;COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	P16949	STMN1	P24941	CDK2	S25	E30K	30	Missense	distal	5	no	14.872	14.739	PhosphoSitePlus;EPSD	ICGC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	P16949	STMN1	P24941	CDK2	S25	E30Q	30	Missense	distal	5	no	14.872	14.753	PhosphoSitePlus;EPSD	ICGC;COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	P16949	STMN1	P24941	CDK2	S25	S31P	31	Missense	distal	6	no	14.872	14.870	PhosphoSitePlus;EPSD	ICGC;COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	P16949	STMN1	P24941	CDK2	S38	S31P	31	Missense	distal	-7	no	17.348	17.528	EPSD;PhosphoSitePlus	ICGC;COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	P12956	XRCC6	P24941	CDK2	S27	K31E	31	Missense	distal	4	no	9.004	8.620	EPSD	ICGC;COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	P12956	XRCC6	P24941	CDK2	S27	L24I	24	Missense	distal	-3	no	9.004	9.095	EPSD	ICGC;COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	P12956	XRCC6	P24941	CDK2	S33	K31E	31	Missense	proximal	-2	no	9.069	8.468	EPSD	ICGC;COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	P12956	XRCC6	P24941	CDK2	T58	P59S	59	Missense	proximal	1	no	10.563	-0.703	EPSD	ICGC	8.148	Loss
CMGC_CDK_CDK2_CDK2_ST	P12956	XRCC6	P24941	CDK2	T58	I64T	64	Missense	distal	6	no	10.563	10.570	EPSD	ICGC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	P12956	XRCC6	P24941	CDK2	T428	Q423K	423	Missense	distal	-5	no	13.162	13.165	EPSD	ICGC;COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	P12956	XRCC6	P24941	CDK2	T455	I452V	452	Missense	distal	-3	no	13.191	13.314	PhosphoSitePlus	ICGC;COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	P12956	XRCC6	P24941	CDK2	T455	G460D	460	Missense	distal	5	no	13.191	13.238	PhosphoSitePlus	ICGC;COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	P12956	XRCC6	P24941	CDK2	S592	L599M	599	Missense	distal	7	no	11.485	12.000	EPSD	ICGC;COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	P52948	NUP98	P24941	CDK2	S231	P232S	232	Missense	proximal	1	no	11.843	0.577	EPSD	ICGC;COSMIC;GDSC;CCLE	8.148	Loss
CMGC_CDK_CDK2_CDK2_ST	P52948	NUP98	P24941	CDK2	S231	T238K	238	Missense	distal	7	no	11.843	11.861	EPSD	ICGC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	P52948	NUP98	P24941	CDK2	S231	T238I	238	Missense	distal	7	no	11.843	12.204	EPSD	ICGC;COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	P52948	NUP98	P24941	CDK2	S839	D845A	845	Missense	distal	6	no	15.080	15.091	EPSD	ICGC;COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	P52948	NUP98	P24941	CDK2	S839	T832I	832	Missense	distal	-7	no	15.080	15.277	EPSD	ICGC;COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	P52948	NUP98	P24941	CDK2	S878	G871C	871	Missense	distal	-7	no	9.661	9.607	EPSD	ICGC;COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	P52948	NUP98	P24941	CDK2	T916	S913R	913	Missense	distal	-3	no	12.024	12.117	EPSD	ICGC;COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	P52948	NUP98	P24941	CDK2	T916	Q914H	914	Missense	proximal	-2	no	12.024	11.581	EPSD	ICGC;COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	P52948	NUP98	P24941	CDK2	T916	S913N	913	Missense	distal	-3	no	12.024	11.949	EPSD	ICGC;COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	P62913	RPL11	P24941	CDK2	S29	R35L	35	Missense	distal	6	no	10.080	10.098	EPSD	ICGC;COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	P62913	RPL11	P24941	CDK2	S29	G27V	27	Missense	proximal	-2	no	10.080	10.173	EPSD	ICGC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	P62913	RPL11	P24941	CDK2	S29	I24V	24	Missense	distal	-5	no	10.080	10.072	EPSD	ICGC;COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	P62913	RPL11	P24941	CDK2	T47	V49E	49	Missense	proximal	2	no	14.735	14.709	PhosphoSitePlus	ICGC;COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	P62913	RPL11	P24941	CDK2	T47	Q46H	46	Missense	proximal	-1	no	14.735	15.162	PhosphoSitePlus	ICGC;GDSC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	P62913	RPL11	P24941	CDK2	T47	L43H	43	Missense	distal	-4	no	14.735	14.189	PhosphoSitePlus	ICGC;COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	Q9C0C2	TNKS1BP1	P24941	CDK2	S14	R18L	18	Missense	distal	4	no	9.834	10.067	EPSD	ICGC;COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	Q9C0C2	TNKS1BP1	P24941	CDK2	T131	A134D	134	Missense	distal	3	no	11.902	10.600	EPSD	ICGC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	Q9C0C2	TNKS1BP1	P24941	CDK2	T131	A137T	137	Missense	distal	6	no	11.902	11.914	EPSD	ICGC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	Q9C0C2	TNKS1BP1	P24941	CDK2	T131	A138S	138	Missense	distal	7	no	11.902	11.365	EPSD	ICGC;COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	Q9C0C2	TNKS1BP1	P24941	CDK2	S178	D180A	180	Missense	proximal	2	no	15.991	16.018	EPSD	ICGC;COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	Q9C0C2	TNKS1BP1	P24941	CDK2	S228	V226L	226	Missense	proximal	-2	no	13.603	14.029	EPSD	ICGC;COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	Q9C0C2	TNKS1BP1	P24941	CDK2	T239	P246S	246	Missense	distal	7	no	12.977	12.825	EPSD	ICGC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	Q9C0C2	TNKS1BP1	P24941	CDK2	T239	S237I	237	Missense	proximal	-2	no	12.977	13.474	EPSD	ICGC;COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	Q9C0C2	TNKS1BP1	P24941	CDK2	S275	P273S	273	Missense	proximal	-2	no	13.397	12.746	EPSD	ICGC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	Q9C0C2	TNKS1BP1	P24941	CDK2	S287	P291L	291	Missense	distal	4	no	14.401	14.513	EPSD	ICGC;COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	Q9C0C2	TNKS1BP1	P24941	CDK2	S287	A292E	292	Missense	distal	5	no	14.401	14.470	EPSD	ICGC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	Q9C0C2	TNKS1BP1	P24941	CDK2	S287	A286V	286	Missense	proximal	-1	no	14.401	14.628	EPSD	ICGC;COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	Q9C0C2	TNKS1BP1	P24941	CDK2	S287	P288L	288	Missense	proximal	1	no	14.401	4.580	EPSD	ICGC	8.148	Loss
CMGC_CDK_CDK2_CDK2_ST	Q9C0C2	TNKS1BP1	P24941	CDK2	S297	A292E	292	Missense	distal	-5	no	8.314	8.326	EPSD	ICGC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	Q9C0C2	TNKS1BP1	P24941	CDK2	S297	G296S	296	Missense	proximal	-1	no	8.314	6.795	EPSD	ICGC	8.148	Loss
CMGC_CDK_CDK2_CDK2_ST	Q9C0C2	TNKS1BP1	P24941	CDK2	S301	G296S	296	Missense	distal	-5	no	14.177	14.053	EPSD	ICGC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	Q9C0C2	TNKS1BP1	P24941	CDK2	S301	H305P	305	Missense	distal	4	no	14.177	14.415	EPSD	ICGC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	Q9C0C2	TNKS1BP1	P24941	CDK2	S311	H305P	305	Missense	distal	-6	no	13.207	13.204	EPSD	ICGC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	Q9C0C2	TNKS1BP1	P24941	CDK2	S329	T322S	322	Missense	distal	-7	no	11.667	11.490	EPSD	ICGC;COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	Q9C0C2	TNKS1BP1	P24941	CDK2	T335	P339R	339	Missense	distal	4	no	12.229	12.108	EPSD	ICGC;COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	Q9C0C2	TNKS1BP1	P24941	CDK2	T351	R349H	349	Missense	proximal	-2	no	12.218	12.444	EPSD	ICGC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	Q9C0C2	TNKS1BP1	P24941	CDK2	S353	R349H	349	Missense	distal	-4	no	13.714	13.353	EPSD	ICGC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	Q9C0C2	TNKS1BP1	P24941	CDK2	S353	G360E	360	Missense	distal	7	no	13.714	13.088	EPSD	ICGC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	Q9C0C2	TNKS1BP1	P24941	CDK2	S369	P370S	370	Missense	proximal	1	no	13.576	2.310	EPSD	ICGC	8.148	Loss
CMGC_CDK_CDK2_CDK2_ST	Q9C0C2	TNKS1BP1	P24941	CDK2	S387	R389Q	389	Missense	proximal	2	no	14.619	14.519	EPSD	ICGC;COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	Q9C0C2	TNKS1BP1	P24941	CDK2	S435	G431V	431	Missense	distal	-4	no	14.171	14.441	EPSD	ICGC;COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	Q9C0C2	TNKS1BP1	P24941	CDK2	S435	G431S	431	Missense	distal	-4	no	14.171	14.844	EPSD	ICGC;COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	Q9C0C2	TNKS1BP1	P24941	CDK2	S435	P436T	436	Missense	proximal	1	no	14.171	4.214	EPSD	ICGC	8.148	Loss
CMGC_CDK_CDK2_CDK2_ST	Q9C0C2	TNKS1BP1	P24941	CDK2	S435	Q438K	438	Missense	distal	3	no	14.171	16.904	EPSD	ICGC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	Q9C0C2	TNKS1BP1	P24941	CDK2	S494	R491W	491	Missense	distal	-3	no	13.077	13.158	EPSD	ICGC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	Q9C0C2	TNKS1BP1	P24941	CDK2	S498	R491W	491	Missense	distal	-7	no	15.064	15.235	EPSD	ICGC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	Q9C0C2	TNKS1BP1	P24941	CDK2	T578	P582R	582	Missense	distal	4	no	12.772	12.652	EPSD	ICGC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	Q9C0C2	TNKS1BP1	P24941	CDK2	S601	E594D	594	Missense	distal	-7	no	14.290	14.441	EPSD	ICGC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	Q9C0C2	TNKS1BP1	P24941	CDK2	S672	E674Q	674	Missense	proximal	2	no	10.728	10.690	EPSD	ICGC;COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	Q9C0C2	TNKS1BP1	P24941	CDK2	S691	G696S	696	Missense	distal	5	no	14.996	14.769	PhosphoSitePlus	ICGC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	Q9C0C2	TNKS1BP1	P24941	CDK2	S691	D686E	686	Missense	distal	-5	no	14.996	14.976	PhosphoSitePlus	ICGC;COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	Q9C0C2	TNKS1BP1	P24941	CDK2	S730	D737E	737	Missense	distal	7	no	8.276	7.634	EPSD	ICGC	8.148	Loss
CMGC_CDK_CDK2_CDK2_ST	Q9C0C2	TNKS1BP1	P24941	CDK2	S730	T735S	735	Missense	distal	5	no	8.276	8.201	EPSD	ICGC;COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	Q9C0C2	TNKS1BP1	P24941	CDK2	S744	D737E	737	Missense	distal	-7	no	15.761	15.610	EPSD	ICGC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	Q9C0C2	TNKS1BP1	P24941	CDK2	S744	S744N	744	Missense	central	0	yes	15.761	0.000	EPSD	ICGC;COSMIC	8.148	Loss
CMGC_CDK_CDK2_CDK2_ST	Q9C0C2	TNKS1BP1	P24941	CDK2	S987	E989K	989	Missense	proximal	2	no	14.426	14.188	EPSD	ICGC;COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	Q9C0C2	TNKS1BP1	P24941	CDK2	S987	P988L	988	Missense	proximal	1	no	14.426	4.605	EPSD	ICGC	8.148	Loss
CMGC_CDK_CDK2_CDK2_ST	Q9C0C2	TNKS1BP1	P24941	CDK2	S987	E989D	989	Missense	proximal	2	no	14.426	14.327	EPSD	ICGC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	Q9C0C2	TNKS1BP1	P24941	CDK2	S1029	F1028L	1028	Missense	proximal	-1	no	14.499	13.534	EPSD	ICGC;COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	Q9C0C2	TNKS1BP1	P24941	CDK2	S1051	S1054R	1054	Missense	distal	3	no	6.980	8.664	EPSD	ICGC	8.148	Gain
CMGC_CDK_CDK2_CDK2_ST	Q9C0C2	TNKS1BP1	P24941	CDK2	S1103	A1100E	1100	Missense	distal	-3	no	14.619	14.852	EPSD	ICGC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	Q9C0C2	TNKS1BP1	P24941	CDK2	S1138	A1135D	1135	Missense	distal	-3	no	16.195	16.319	EPSD	ICGC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	Q9C0C2	TNKS1BP1	P24941	CDK2	S1297	G1299R	1299	Missense	proximal	2	no	13.030	13.072	EPSD	ICGC;COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	Q9C0C2	TNKS1BP1	P24941	CDK2	S1297	A1291T	1291	Missense	distal	-6	no	13.030	13.031	EPSD	ICGC;COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	Q9C0C2	TNKS1BP1	P24941	CDK2	S1297	P1298S	1298	Missense	proximal	1	no	13.030	1.765	EPSD	ICGC;COSMIC	8.148	Loss
CMGC_CDK_CDK2_CDK2_ST	Q9C0C2	TNKS1BP1	P24941	CDK2	S1297	A1294E	1294	Missense	distal	-3	no	13.030	13.263	EPSD	ICGC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	Q9C0C2	TNKS1BP1	P24941	CDK2	S1371	V1370A	1370	Missense	proximal	-1	no	9.296	9.069	EPSD	ICGC;COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	Q9C0C2	TNKS1BP1	P24941	CDK2	S1371	G1377R	1377	Missense	distal	6	no	9.296	9.291	EPSD	ICGC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	Q9C0C2	TNKS1BP1	P24941	CDK2	S1452	S1450P	1450	Missense	proximal	-2	no	7.538	8.189	EPSD	ICGC	8.148	Gain
CMGC_CDK_CDK2_CDK2_ST	Q9C0C2	TNKS1BP1	P24941	CDK2	S1503	P1499T	1499	Missense	distal	-4	no	11.873	12.039	EPSD	ICGC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	Q9C0C2	TNKS1BP1	P24941	CDK2	S1503	L1497R	1497	Missense	distal	-6	no	11.873	11.875	EPSD	ICGC;COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	Q9C0C2	TNKS1BP1	P24941	CDK2	S1602	A1604V	1604	Missense	proximal	2	no	9.221	9.319	EPSD	ICGC;COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	Q9C0C2	TNKS1BP1	P24941	CDK2	S1602	F1607L	1607	Missense	distal	5	no	9.221	9.043	EPSD	ICGC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	Q9C0C2	TNKS1BP1	P24941	CDK2	S1652	A1655D	1655	Missense	distal	3	no	12.454	11.152	EPSD	ICGC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	Q9C0C2	TNKS1BP1	P24941	CDK2	S1652	K1657N	1657	Missense	distal	5	no	12.454	12.611	EPSD	ICGC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	Q14247	CTTN	P24941	CDK2	S47	K42N	42	Missense	distal	-5	no	8.721	8.737	EPSD	ICGC;COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	Q14247	CTTN	P24941	CDK2	S47	T43M	43	Missense	distal	-4	no	8.721	7.806	EPSD	ICGC;COSMIC	8.148	Loss
CMGC_CDK_CDK2_CDK2_ST	Q14247	CTTN	P24941	CDK2	S47	G46V	46	Missense	proximal	-1	no	8.721	7.629	EPSD	ICGC;COSMIC	8.148	Loss
CMGC_CDK_CDK2_CDK2_ST	Q14247	CTTN	P24941	CDK2	S47	G48R	48	Missense	proximal	1	no	8.721	6.234	EPSD	ICGC;COSMIC	8.148	Loss
CMGC_CDK_CDK2_CDK2_ST	Q14247	CTTN	P24941	CDK2	T68	L69P	69	Missense	proximal	1	no	3.440	13.261	EPSD	ICGC	8.148	Gain
CMGC_CDK_CDK2_CDK2_ST	Q14247	CTTN	P24941	CDK2	T76	H82R	82	Missense	distal	6	no	10.372	10.360	EPSD	ICGC;COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	Q14247	CTTN	P24941	CDK2	T76	L69I	69	Missense	distal	-7	no	10.372	10.560	EPSD	ICGC;COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	Q14247	CTTN	P24941	CDK2	T76	L69P	69	Missense	distal	-7	no	10.372	10.366	EPSD	ICGC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	Q14247	CTTN	P24941	CDK2	T401	T401M	401	Missense	central	0	yes	13.290	0.000	EPSD	ICGC;COSMIC	8.148	Loss
CMGC_CDK_CDK2_CDK2_ST	Q14247	CTTN	P24941	CDK2	T401	T401A	401	Missense	central	0	yes	13.290	0.000	EPSD	ICGC	8.148	Loss
CMGC_CDK_CDK2_CDK2_ST	Q14247	CTTN	P24941	CDK2	T401	S405L	405	Missense	distal	4	no	13.290	13.388	EPSD	ICGC;COSMIC;GDSC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	Q14247	CTTN	P24941	CDK2	T401	A407T	407	Missense	distal	6	no	13.290	13.302	EPSD	ICGC;COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	Q14247	CTTN	P24941	CDK2	S405	E412K	412	Missense	distal	7	no	14.637	14.306	PhosphoSitePlus	ICGC;COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	Q14247	CTTN	P24941	CDK2	S405	T401M	401	Missense	distal	-4	no	14.637	13.722	PhosphoSitePlus	ICGC;COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	Q14247	CTTN	P24941	CDK2	S405	T401A	401	Missense	distal	-4	no	14.637	14.411	PhosphoSitePlus	ICGC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	Q14247	CTTN	P24941	CDK2	S405	S405L	405	Missense	central	0	yes	14.637	0.000	PhosphoSitePlus	ICGC;COSMIC;GDSC	8.148	Loss
CMGC_CDK_CDK2_CDK2_ST	Q14247	CTTN	P24941	CDK2	S405	A407T	407	Missense	proximal	2	no	14.637	14.435	PhosphoSitePlus	ICGC;COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	Q14247	CTTN	P24941	CDK2	S418	E412K	412	Missense	distal	-6	no	14.847	14.845	EPSD	ICGC;COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	Q14247	CTTN	P24941	CDK2	S418	L415P	415	Missense	distal	-3	no	14.847	14.918	EPSD	ICGC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	Q14247	CTTN	P24941	CDK2	S418	A424V	424	Missense	distal	6	no	14.847	14.850	EPSD	ICGC;COSMIC;GDSC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	P31749	AKT1	P24941	CDK2	T92	H89R	89	Missense	distal	-3	no	13.919	13.962	EPSD	ICGC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	P31749	AKT1	P24941	CDK2	T92	E85K	85	Missense	distal	-7	no	13.919	13.782	EPSD	ICGC;COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	P31749	AKT1	P24941	CDK2	T92	R96L	96	Missense	distal	4	no	13.919	14.151	EPSD	ICGC;COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	P31749	AKT1	P24941	CDK2	S137	R144H	144	Missense	distal	7	no	8.832	8.474	EPSD	ICGC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	P31749	AKT1	P24941	CDK2	T312	T305N	305	Missense	distal	-7	no	15.064	14.986	EPSD	ICGC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	P31749	AKT1	P24941	CDK2	S422	K420T	420	Missense	proximal	-2	no	15.215	15.696	EPSD	ICGC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	P31749	AKT1	P24941	CDK2	T450	Q454K	454	Missense	distal	4	no	8.766	9.107	EPSD	ICGC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	P31749	AKT1	P24941	CDK2	T450	S457R	457	Missense	distal	7	no	8.766	9.408	EPSD	ICGC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	P82970	HMGN5	P24941	CDK2	T31	A25D	25	Missense	distal	-6	no	15.847	15.846	PhosphoSitePlus	ICGC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	P82970	HMGN5	P24941	CDK2	T31	P29T	29	Missense	proximal	-2	no	15.847	15.813	PhosphoSitePlus	ICGC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	Q9H8Y8	GORASP2	P24941	CDK2	S26	V22L	22	Missense	distal	-4	no	15.767	15.756	EPSD	ICGC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	Q9H8Y8	GORASP2	P24941	CDK2	S26	P27L	27	Missense	proximal	1	no	15.767	5.946	EPSD	ICGC;COSMIC	8.148	Loss
CMGC_CDK_CDK2_CDK2_ST	Q9H8Y8	GORASP2	P24941	CDK2	S26	Q23K	23	Missense	distal	-3	no	15.767	15.668	EPSD	ICGC;COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	Q9H8Y8	GORASP2	P24941	CDK2	S26	S26I	26	Missense	central	0	yes	15.767	0.000	EPSD	ICGC	8.148	Loss
CMGC_CDK_CDK2_CDK2_ST	Q9H8Y8	GORASP2	P24941	CDK2	T204	R205H	205	Missense	proximal	1	no	5.481	8.521	EPSD	ICGC;COSMIC	8.148	Gain
CMGC_CDK_CDK2_CDK2_ST	Q9H8Y8	GORASP2	P24941	CDK2	T222	M219V	219	Missense	distal	-3	no	13.618	13.392	EPSD	ICGC;COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	Q9H8Y8	GORASP2	P24941	CDK2	T222	G221D	221	Missense	proximal	-1	no	13.618	13.325	EPSD	ICGC;COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	Q9H8Y8	GORASP2	P24941	CDK2	T225	M219V	219	Missense	distal	-6	no	17.101	17.095	PhosphoSitePlus	ICGC;COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	Q9H8Y8	GORASP2	P24941	CDK2	T225	G221D	221	Missense	distal	-4	no	17.101	17.946	PhosphoSitePlus	ICGC;COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	Q9H8Y8	GORASP2	P24941	CDK2	S245	P242L	242	Missense	distal	-3	no	13.398	13.327	EPSD	ICGC;COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	Q9H8Y8	GORASP2	P24941	CDK2	T415	T415M	415	Missense	central	0	yes	11.553	0.000	EPSD	ICGC;COSMIC	8.148	Loss
CMGC_CDK_CDK2_CDK2_ST	Q9H8Y8	GORASP2	P24941	CDK2	T433	V440D	440	Missense	distal	7	no	15.225	15.653	EPSD	ICGC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	Q9H8Y8	GORASP2	P24941	CDK2	T433	S432F	432	Missense	proximal	-1	no	15.225	16.482	EPSD	ICGC;COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	Q9H8Y8	GORASP2	P24941	CDK2	T433	E437K	437	Missense	distal	4	no	15.225	15.610	EPSD	ICGC;COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	Q9Y253	POLH	P24941	CDK2	S396	A392T	392	Missense	distal	-4	no	8.442	8.667	EPSD	ICGC;COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	Q9Y253	POLH	P24941	CDK2	S396	I403M	403	Missense	distal	7	no	8.442	8.930	EPSD	ICGC;COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	Q9Y253	POLH	P24941	CDK2	S396	H393Q	393	Missense	distal	-3	no	8.442	8.354	EPSD	ICGC;COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	Q9Y253	POLH	P24941	CDK2	S396	R389S	389	Missense	distal	-7	no	8.442	7.919	EPSD	ICGC;COSMIC	8.148	Loss
CMGC_CDK_CDK2_CDK2_ST	Q9Y253	POLH	P24941	CDK2	S512	P508L	508	Missense	distal	-4	no	16.722	16.664	EPSD	ICGC;COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	Q9Y253	POLH	P24941	CDK2	S551	S558F	558	Missense	distal	7	no	12.897	13.751	EPSD	ICGC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	Q9Y253	POLH	P24941	CDK2	S551	S548L	548	Missense	distal	-3	no	12.897	12.731	EPSD	ICGC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	Q9Y253	POLH	P24941	CDK2	S551	N546K	546	Missense	distal	-5	no	12.897	12.881	EPSD	ICGC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	P25054	APC	P24941	CDK2	S306	R302P	302	Missense	distal	-4	no	8.301	8.544	EPSD	ICGC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	P25054	APC	P24941	CDK2	S306	R302L	302	Missense	distal	-4	no	8.301	8.486	EPSD	ICGC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	P25054	APC	P24941	CDK2	S306	S306I	306	Missense	central	0	yes	8.301	0.000	EPSD	ICGC	8.148	Loss
CMGC_CDK_CDK2_CDK2_ST	P25054	APC	P24941	CDK2	S306	V312L	312	Missense	distal	6	no	8.301	8.304	EPSD	ICGC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	P25054	APC	P24941	CDK2	T324	D326Y	326	Missense	proximal	2	no	10.214	10.275	EPSD	ICGC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	P25054	APC	P24941	CDK2	T324	M321I	321	Missense	distal	-3	no	10.214	9.865	EPSD	ICGC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	P25054	APC	P24941	CDK2	T324	D329Y	329	Missense	distal	5	no	10.214	10.113	EPSD	ICGC;COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	P25054	APC	P24941	CDK2	T324	D328V	328	Missense	distal	4	no	10.214	10.506	EPSD	ICGC;COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	P25054	APC	P24941	CDK2	S744	S748I	748	Missense	distal	4	no	16.598	16.556	EPSD	ICGC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	P25054	APC	P24941	CDK2	S744	P750S	750	Missense	distal	6	no	16.598	16.599	EPSD	ICGC;COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	P25054	APC	P24941	CDK2	S780	R786C	786	Missense	distal	6	no	12.949	12.952	EPSD	ICGC;COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	P25054	APC	P24941	CDK2	S844	R845H	845	Missense	proximal	1	no	5.762	8.802	EPSD	ICGC;COSMIC	8.148	Gain
CMGC_CDK_CDK2_CDK2_ST	P25054	APC	P24941	CDK2	T1023	S1028R	1028	Missense	distal	5	no	11.779	11.986	EPSD	ICGC;COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	P25054	APC	P24941	CDK2	S1042	W1049L	1049	Missense	distal	7	no	14.087	13.228	EPSD	ICGC;COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	P25054	APC	P24941	CDK2	S1042	R1040S	1040	Missense	proximal	-2	no	14.087	14.672	EPSD	ICGC;COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	P25054	APC	P24941	CDK2	S1042	R1040T	1040	Missense	proximal	-2	no	14.087	15.290	EPSD	ICGC;COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	P25054	APC	P24941	CDK2	S1042	P1043S	1043	Missense	proximal	1	no	14.087	2.821	EPSD	ICGC	8.148	Loss
CMGC_CDK_CDK2_CDK2_ST	P25054	APC	P24941	CDK2	S1042	Q1041E	1041	Missense	proximal	-1	no	14.087	15.180	EPSD	ICGC;COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	P25054	APC	P24941	CDK2	T1082	E1080K	1080	Missense	proximal	-2	no	7.885	8.486	EPSD	ICGC;COSMIC	8.148	Gain
CMGC_CDK_CDK2_CDK2_ST	P25054	APC	P24941	CDK2	S1100	A1107V	1107	Missense	distal	7	no	16.142	16.015	EPSD	ICGC;COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	P25054	APC	P24941	CDK2	S1100	R1105W	1105	Missense	distal	5	no	16.142	16.308	EPSD	ICGC;COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	P25054	APC	P24941	CDK2	T1220	T1218A	1218	Missense	proximal	-2	no	11.148	11.198	EPSD	ICGC;GDSC;CCLE	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	P25054	APC	P24941	CDK2	T1267	E1265D	1265	Missense	proximal	-2	no	7.722	8.703	EPSD	ICGC;COSMIC	8.148	Gain
CMGC_CDK_CDK2_CDK2_ST	P25054	APC	P24941	CDK2	S1360	A1366V	1366	Missense	distal	6	no	16.350	16.352	PhosphoSitePlus	ICGC;COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	P25054	APC	P24941	CDK2	T1368	A1366V	1366	Missense	proximal	-2	no	14.571	13.905	EPSD	ICGC;COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	P25054	APC	P24941	CDK2	S1371	A1366V	1366	Missense	distal	-5	no	11.727	11.733	EPSD	ICGC;COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	P25054	APC	P24941	CDK2	T1380	P1381T	1381	Missense	proximal	1	no	13.550	3.593	EPSD	ICGC;COSMIC	8.148	Loss
CMGC_CDK_CDK2_CDK2_ST	P25054	APC	P24941	CDK2	T1380	R1386I	1386	Missense	distal	6	no	13.550	13.566	EPSD	ICGC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	P25054	APC	P24941	CDK2	S1426	S1419N	1419	Missense	distal	-7	no	13.446	13.545	EPSD	ICGC;COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	P25054	APC	P24941	CDK2	S1426	Q1429R	1429	Missense	distal	3	no	13.446	15.190	EPSD	ICGC;COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	P25054	APC	P24941	CDK2	S1426	M1431T	1431	Missense	distal	5	no	13.446	13.113	EPSD	ICGC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	P25054	APC	P24941	CDK2	T1438	R1435K	1435	Missense	distal	-3	no	11.310	11.080	EPSD	ICGC;COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	P25054	APC	P24941	CDK2	T1438	M1431T	1431	Missense	distal	-7	no	11.310	10.806	EPSD	ICGC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	P25054	APC	P24941	CDK2	T1633	G1635R	1635	Missense	proximal	2	no	13.131	13.172	EPSD	ICGC;COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	P25054	APC	P24941	CDK2	T1633	G1635W	1635	Missense	proximal	2	no	13.131	13.269	EPSD	ICGC;COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	P25054	APC	P24941	CDK2	T1647	T1647A	1647	Missense	central	0	yes	12.866	0.000	EPSD	ICGC	8.148	Loss
CMGC_CDK_CDK2_CDK2_ST	P25054	APC	P24941	CDK2	S1664	P1665S	1665	Missense	proximal	1	no	13.896	2.630	EPSD	ICGC;COSMIC	8.148	Loss
CMGC_CDK_CDK2_CDK2_ST	P25054	APC	P24941	CDK2	S1774	G1767C	1767	Missense	distal	-7	no	16.256	16.203	EPSD	ICGC;COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	P25054	APC	P24941	CDK2	S1842	F1840V	1840	Missense	proximal	-2	no	13.113	13.576	EPSD	ICGC;COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	P25054	APC	P24941	CDK2	S1842	R1835S	1835	Missense	distal	-7	no	13.113	12.589	EPSD	ICGC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	P25054	APC	P24941	CDK2	T1847	F1840V	1840	Missense	distal	-7	no	14.877	14.525	EPSD	ICGC;COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	P25054	APC	P24941	CDK2	T1852	R1858L	1858	Missense	distal	6	no	9.471	9.488	EPSD	ICGC;COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	P25054	APC	P24941	CDK2	S2054	K2052N	2052	Missense	proximal	-2	no	8.459	7.630	EPSD	ICGC;COSMIC	8.148	Loss
CMGC_CDK_CDK2_CDK2_ST	P25054	APC	P24941	CDK2	S2064	P2065S	2065	Missense	proximal	1	no	12.880	1.614	EPSD	ICGC;COSMIC	8.148	Loss
CMGC_CDK_CDK2_CDK2_ST	P25054	APC	P24941	CDK2	S2146	G2145R	2145	Missense	proximal	-1	no	16.096	15.618	EPSD	ICGC;COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	P25054	APC	P24941	CDK2	S2146	L2144M	2144	Missense	proximal	-2	no	16.096	14.236	EPSD	ICGC;COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	P25054	APC	P24941	CDK2	T2151	L2144M	2144	Missense	distal	-7	no	12.566	13.062	EPSD	ICGC;COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	P25054	APC	P24941	CDK2	T2151	Q2154P	2154	Missense	distal	3	no	12.566	12.591	EPSD	ICGC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	P25054	APC	P24941	CDK2	S2183	S2183Y	2183	Missense	central	0	yes	8.354	0.000	EPSD	ICGC;COSMIC	8.148	Loss
CMGC_CDK_CDK2_CDK2_ST	P25054	APC	P24941	CDK2	S2183	E2184G	2184	Missense	proximal	1	no	8.354	10.208	EPSD	ICGC;COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	P25054	APC	P24941	CDK2	S2283	V2278L	2278	Missense	distal	-5	no	10.757	10.738	EPSD	ICGC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	P25054	APC	P24941	CDK2	T2308	R2305T	2305	Missense	distal	-3	no	15.857	15.629	EPSD	ICGC;COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	P25054	APC	P24941	CDK2	T2308	R2311I	2311	Missense	distal	3	no	15.857	13.471	EPSD	ICGC;COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	P25054	APC	P24941	CDK2	S2323	Q2322H	2322	Missense	proximal	-1	no	14.191	14.617	EPSD	ICGC;COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	P25054	APC	P24941	CDK2	S2323	S2330F	2330	Missense	distal	7	no	14.191	15.044	EPSD	ICGC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	P25054	APC	P24941	CDK2	S2323	P2324H	2324	Missense	proximal	1	no	14.191	7.432	EPSD	ICGC;COSMIC	8.148	Loss
CMGC_CDK_CDK2_CDK2_ST	P25054	APC	P24941	CDK2	S2330	R2333T	2333	Missense	distal	3	no	11.612	9.779	EPSD	ICGC;COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	P25054	APC	P24941	CDK2	S2330	G2332S	2332	Missense	proximal	2	no	11.612	11.561	EPSD	ICGC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	P25054	APC	P24941	CDK2	S2330	S2330F	2330	Missense	central	0	yes	11.612	0.000	EPSD	ICGC	8.148	Loss
CMGC_CDK_CDK2_CDK2_ST	P25054	APC	P24941	CDK2	S2330	P2324H	2324	Missense	distal	-6	no	11.612	11.615	EPSD	ICGC;COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	P25054	APC	P24941	CDK2	S2337	R2333T	2333	Missense	distal	-4	no	12.341	12.750	EPSD	ICGC;COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	P25054	APC	P24941	CDK2	S2337	P2338H	2338	Missense	proximal	1	no	12.341	5.582	EPSD	ICGC	8.148	Loss
CMGC_CDK_CDK2_CDK2_ST	P25054	APC	P24941	CDK2	S2337	G2332S	2332	Missense	distal	-5	no	12.341	12.217	EPSD	ICGC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	P25054	APC	P24941	CDK2	S2337	S2330F	2330	Missense	distal	-7	no	12.341	12.892	EPSD	ICGC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	P25054	APC	P24941	CDK2	S2350	S2350F	2350	Missense	central	0	yes	13.220	0.000	EPSD	ICGC;COSMIC	8.148	Loss
CMGC_CDK_CDK2_CDK2_ST	P25054	APC	P24941	CDK2	S2350	K2357T	2357	Missense	distal	7	no	13.220	13.202	EPSD	ICGC;COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	P25054	APC	P24941	CDK2	S2368	M2364I	2364	Missense	distal	-4	no	16.725	17.322	EPSD	ICGC;COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	P25054	APC	P24941	CDK2	S2466	S2464C	2464	Missense	proximal	-2	no	11.045	10.635	EPSD	ICGC;COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	P25054	APC	P24941	CDK2	S2466	R2470I	2470	Missense	distal	4	no	11.045	11.137	EPSD	ICGC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	P25054	APC	P24941	CDK2	S2466	S2469F	2469	Missense	distal	3	no	11.045	10.970	EPSD	ICGC;COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	P25054	APC	P24941	CDK2	S2466	S2459F	2459	Missense	distal	-7	no	11.045	11.596	EPSD	ICGC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	P25054	APC	P24941	CDK2	S2473	R2470I	2470	Missense	distal	-3	no	14.466	14.297	EPSD	ICGC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	P25054	APC	P24941	CDK2	S2473	S2469F	2469	Missense	distal	-4	no	14.466	13.504	EPSD	ICGC;COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	P25054	APC	P24941	CDK2	S2512	D2519V	2519	Missense	distal	7	no	12.667	12.239	EPSD	ICGC;COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	P25054	APC	P24941	CDK2	S2512	L2511F	2511	Missense	proximal	-1	no	12.667	13.633	EPSD	ICGC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	P25054	APC	P24941	CDK2	S2512	R2505Q	2505	Missense	distal	-7	no	12.667	12.281	EPSD	ICGC;COSMIC;GDSC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	P25054	APC	P24941	CDK2	S2531	R2525H	2525	Missense	distal	-6	no	9.125	9.126	EPSD	ICGC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	P25054	APC	P24941	CDK2	S2621	S2621C	2621	Missense	central	0	yes	11.510	0.000	EPSD	ICGC;COSMIC;GDSC	8.148	Loss
CMGC_CDK_CDK2_CDK2_ST	P25054	APC	P24941	CDK2	S2621	S2625C	2625	Missense	distal	4	no	11.510	10.750	EPSD	ICGC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	P25054	APC	P24941	CDK2	S2674	G2672E	2672	Missense	proximal	-2	no	10.985	10.612	EPSD	ICGC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	P25054	APC	P24941	CDK2	T2679	V2682L	2682	Missense	distal	3	no	14.248	13.256	EPSD	ICGC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	P25054	APC	P24941	CDK2	T2679	G2672E	2672	Missense	distal	-7	no	14.248	14.013	EPSD	ICGC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	P25054	APC	P24941	CDK2	T2760	S2755T	2755	Missense	distal	-5	no	13.102	13.145	EPSD	ICGC;COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	P25054	APC	P24941	CDK2	S2789	R2791W	2791	Missense	proximal	2	no	17.055	17.152	EPSD	ICGC;COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	P25054	APC	P24941	CDK2	S2789	S2793I	2793	Missense	distal	4	no	17.055	17.013	EPSD	ICGC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	P25054	APC	P24941	CDK2	S2789	S2794I	2794	Missense	distal	5	no	17.055	17.249	EPSD	ICGC;COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	P25054	APC	P24941	CDK2	T2807	P2808A	2808	Missense	proximal	1	no	13.457	-0.946	EPSD	ICGC;COSMIC	8.148	Loss
CMGC_CDK_CDK2_CDK2_ST	P25054	APC	P24941	CDK2	S2830	S2837A	2837	Missense	distal	7	no	15.826	16.363	EPSD	ICGC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	P25054	APC	P24941	CDK2	S2830	G2836W	2836	Missense	distal	6	no	15.826	15.813	EPSD	ICGC;COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	Q99626	CDX2	P24941	CDK2	S60	P66L	66	Missense	distal	6	no	15.238	15.239	EPSD	ICGC;COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	Q99626	CDX2	P24941	CDK2	S283	P284L	284	Missense	proximal	1	no	15.969	6.148	PhosphoSitePlus	ICGC	8.148	Loss
CMGC_CDK_CDK2_CDK2_ST	Q99626	CDX2	P24941	CDK2	S283	P284T	284	Missense	proximal	1	no	15.969	6.012	PhosphoSitePlus	ICGC	8.148	Loss
CMGC_CDK_CDK2_CDK2_ST	Q13118	KLF10	P24941	CDK2	S97	S104A	104	Missense	distal	7	no	13.807	14.343	EPSD	ICGC;COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	Q9C0C9	UBE2O	P24941	CDK2	S322	I328F	328	Missense	distal	6	no	13.907	13.889	EPSD	ICGC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	Q9C0C9	UBE2O	P24941	CDK2	S322	G316W	316	Missense	distal	-6	no	13.907	13.913	EPSD	ICGC;COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	Q9C0C9	UBE2O	P24941	CDK2	S401	R396Q	396	Missense	distal	-5	no	15.375	15.328	EPSD	ICGC;COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	Q9C0C9	UBE2O	P24941	CDK2	S836	T838N	838	Missense	proximal	2	no	13.935	14.042	PhosphoSitePlus	ICGC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	Q9C0C9	UBE2O	P24941	CDK2	S839	T838N	838	Missense	proximal	-1	no	13.018	13.208	EPSD	ICGC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	Q9C0C9	UBE2O	P24941	CDK2	T906	Q912H	912	Missense	distal	6	no	13.623	13.613	EPSD	ICGC;COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	Q9C0C9	UBE2O	P24941	CDK2	S1168	P1171H	1171	Missense	distal	3	no	14.767	15.789	EPSD	ICGC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	Q9C0C9	UBE2O	P24941	CDK2	S1168	P1171T	1171	Missense	distal	3	no	14.767	14.653	EPSD	ICGC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	Q9C0C9	UBE2O	P24941	CDK2	S1168	G1161W	1161	Missense	distal	-7	no	14.767	14.957	EPSD	ICGC;COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	P23258	TUBG1	P24941	CDK2	S80	P81T	81	Missense	proximal	1	no	15.010	5.052	PhosphoSitePlus	ICGC;COSMIC	8.148	Loss
CMGC_CDK_CDK2_CDK2_ST	P23258	TUBG1	P24941	CDK2	S179	D180G	180	Missense	proximal	1	no	7.765	8.697	EPSD	ICGC;COSMIC	8.148	Gain
CMGC_CDK_CDK2_CDK2_ST	P23258	TUBG1	P24941	CDK2	T263	S259L	259	Missense	distal	-4	no	14.674	14.261	EPSD	ICGC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	P23258	TUBG1	P24941	CDK2	T274	L276V	276	Missense	proximal	2	no	11.231	11.460	EPSD	ICGC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	P23258	TUBG1	P24941	CDK2	S364	A359S	359	Missense	distal	-5	no	11.482	11.413	EPSD	ICGC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	Q9ULW0	TPX2	P24941	CDK2	T59	G53W	53	Missense	distal	-6	no	12.983	12.988	EPSD	ICGC;COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	Q9ULW0	TPX2	P24941	CDK2	T59	Q56H	56	Missense	distal	-3	no	12.983	13.071	EPSD	ICGC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	Q9ULW0	TPX2	P24941	CDK2	T59	A64S	64	Missense	distal	5	no	12.983	12.872	EPSD	ICGC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	Q9ULW0	TPX2	P24941	CDK2	T72	V71F	71	Missense	proximal	-1	no	14.194	15.023	PhosphoSitePlus	ICGC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	Q9ULW0	TPX2	P24941	CDK2	T147	R144I	144	Missense	distal	-3	no	11.943	11.774	EPSD	ICGC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	Q9ULW0	TPX2	P24941	CDK2	T147	I151T	151	Missense	distal	4	no	11.943	12.254	EPSD	ICGC;COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	Q9ULW0	TPX2	P24941	CDK2	T147	D152N	152	Missense	distal	5	no	11.943	11.872	EPSD	ICGC;GDSC;CCLE	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	Q9ULW0	TPX2	P24941	CDK2	S186	K182N	182	Missense	distal	-4	no	16.123	16.342	EPSD	ICGC;COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	Q9ULW0	TPX2	P24941	CDK2	S310	P306T	306	Missense	distal	-4	no	8.109	8.275	EPSD	ICGC;COSMIC	8.148	Gain
CMGC_CDK_CDK2_CDK2_ST	Q9ULW0	TPX2	P24941	CDK2	S310	I303F	303	Missense	distal	-7	no	8.109	8.286	EPSD	ICGC;COSMIC	8.148	Gain
CMGC_CDK_CDK2_CDK2_ST	Q9ULW0	TPX2	P24941	CDK2	S310	G312R	312	Missense	proximal	2	no	8.109	8.150	EPSD	ICGC	8.148	Gain
CMGC_CDK_CDK2_CDK2_ST	O14686	KMT2D	P24941	CDK2	S48	P55H	55	Missense	distal	7	no	14.332	14.464	EPSD	ICGC;COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	O14686	KMT2D	P24941	CDK2	T54	P55H	55	Missense	proximal	1	no	9.652	2.893	EPSD	ICGC;COSMIC	8.148	Loss
CMGC_CDK_CDK2_CDK2_ST	O14686	KMT2D	P24941	CDK2	S98	S102R	102	Missense	distal	4	no	13.562	13.429	EPSD	ICGC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	O14686	KMT2D	P24941	CDK2	S98	G100E	100	Missense	proximal	2	no	13.562	13.541	EPSD	ICGC;COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	O14686	KMT2D	P24941	CDK2	S98	R93L	93	Missense	distal	-5	no	13.562	13.527	EPSD	ICGC;COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	O14686	KMT2D	P24941	CDK2	S102	S102R	102	Missense	central	0	yes	13.742	0.000	EPSD	ICGC	8.148	Loss
CMGC_CDK_CDK2_CDK2_ST	O14686	KMT2D	P24941	CDK2	S102	G100E	100	Missense	proximal	-2	no	13.742	13.369	EPSD	ICGC;COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	O14686	KMT2D	P24941	CDK2	T366	S370R	370	Missense	distal	4	no	11.166	11.032	EPSD	ICGC;COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	O14686	KMT2D	P24941	CDK2	T366	T366I	366	Missense	central	0	yes	11.166	0.000	EPSD	ICGC	8.148	Loss
CMGC_CDK_CDK2_CDK2_ST	O14686	KMT2D	P24941	CDK2	T366	S360F	360	Missense	distal	-6	no	11.166	11.171	EPSD	ICGC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	O14686	KMT2D	P24941	CDK2	S373	S370R	370	Missense	distal	-3	no	16.228	16.322	EPSD	ICGC;COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	O14686	KMT2D	P24941	CDK2	S373	T366I	366	Missense	distal	-7	no	16.228	16.425	EPSD	ICGC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	O14686	KMT2D	P24941	CDK2	T380	P381T	381	Missense	proximal	1	no	9.145	-0.812	EPSD	ICGC	8.148	Loss
CMGC_CDK_CDK2_CDK2_ST	O14686	KMT2D	P24941	CDK2	S477	A482S	482	Missense	distal	5	no	11.570	11.459	EPSD	ICGC;COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	O14686	KMT2D	P24941	CDK2	S606	L599V	599	Missense	distal	-7	no	13.374	13.388	EPSD	ICGC;COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	O14686	KMT2D	P24941	CDK2	S615	P621H	621	Missense	distal	6	no	13.518	13.513	EPSD	ICGC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	O14686	KMT2D	P24941	CDK2	S615	L617F	617	Missense	proximal	2	no	13.518	13.875	EPSD	ICGC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	O14686	KMT2D	P24941	CDK2	S618	P621H	621	Missense	distal	3	no	13.691	14.713	EPSD	ICGC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	O14686	KMT2D	P24941	CDK2	S618	L617F	617	Missense	proximal	-1	no	13.691	14.656	EPSD	ICGC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	O14686	KMT2D	P24941	CDK2	S627	P621H	621	Missense	distal	-6	no	12.679	12.683	EPSD	ICGC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	O14686	KMT2D	P24941	CDK2	S645	V650L	650	Missense	distal	5	no	13.230	13.303	EPSD	ICGC;COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	O14686	KMT2D	P24941	CDK2	S645	R652C	652	Missense	distal	7	no	13.230	13.381	EPSD	ICGC;COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	O14686	KMT2D	P24941	CDK2	S654	V650L	650	Missense	distal	-4	no	11.205	11.195	EPSD	ICGC;COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	O14686	KMT2D	P24941	CDK2	S654	S654F	654	Missense	central	0	yes	11.205	0.000	EPSD	ICGC;COSMIC	8.148	Loss
CMGC_CDK_CDK2_CDK2_ST	O14686	KMT2D	P24941	CDK2	S654	R652C	652	Missense	proximal	-2	no	11.205	11.379	EPSD	ICGC;COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	O14686	KMT2D	P24941	CDK2	S663	P664T	664	Missense	proximal	1	no	11.009	1.052	EPSD	ICGC;COSMIC	8.148	Loss
CMGC_CDK_CDK2_CDK2_ST	O14686	KMT2D	P24941	CDK2	S669	P664T	664	Missense	distal	-5	no	12.383	12.381	EPSD	ICGC;COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	O14686	KMT2D	P24941	CDK2	S678	T680M	680	Missense	proximal	2	no	12.374	12.762	EPSD	ICGC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	O14686	KMT2D	P24941	CDK2	S681	T680M	680	Missense	proximal	-1	no	12.996	14.309	EPSD	ICGC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	O14686	KMT2D	P24941	CDK2	S762	E766D	766	Missense	distal	4	no	12.215	12.133	EPSD	ICGC;COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	O14686	KMT2D	P24941	CDK2	S1037	S1043Y	1043	Missense	distal	6	no	10.916	10.906	EPSD	ICGC;COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	O14686	KMT2D	P24941	CDK2	S1037	H1030R	1030	Missense	distal	-7	no	10.916	11.136	EPSD	ICGC;COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	O14686	KMT2D	P24941	CDK2	S1037	P1039H	1039	Missense	proximal	2	no	10.916	10.993	EPSD	ICGC;COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	O14686	KMT2D	P24941	CDK2	S1043	S1043Y	1043	Missense	central	0	yes	10.603	0.000	EPSD	ICGC;COSMIC	8.148	Loss
CMGC_CDK_CDK2_CDK2_ST	O14686	KMT2D	P24941	CDK2	S1043	P1039H	1039	Missense	distal	-4	no	10.603	9.999	EPSD	ICGC;COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	O14686	KMT2D	P24941	CDK2	S1146	A1145D	1145	Missense	proximal	-1	no	8.404	9.430	EPSD	ICGC;COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	O14686	KMT2D	P24941	CDK2	T1164	P1170H	1170	Missense	distal	6	no	13.764	13.759	EPSD	ICGC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	O14686	KMT2D	P24941	CDK2	T1164	Y1169C	1169	Missense	distal	5	no	13.764	13.924	EPSD	ICGC;COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	O14686	KMT2D	P24941	CDK2	S1180	T1175I	1175	Missense	distal	-5	no	16.075	16.115	EPSD	ICGC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	O14686	KMT2D	P24941	CDK2	S1180	Q1178K	1178	Missense	proximal	-2	no	16.075	16.127	EPSD	ICGC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	O14686	KMT2D	P24941	CDK2	T1195	P1194H	1194	Missense	proximal	-1	no	14.225	14.344	EPSD	ICGC;COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	O14686	KMT2D	P24941	CDK2	S1249	T1246M	1246	Missense	distal	-3	no	16.439	16.847	EPSD	ICGC;COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	O14686	KMT2D	P24941	CDK2	S1294	R1297H	1297	Missense	distal	3	no	15.567	14.870	EPSD	ICGC;COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	O14686	KMT2D	P24941	CDK2	S1294	R1299S	1299	Missense	distal	5	no	15.567	15.360	EPSD	ICGC;COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	O14686	KMT2D	P24941	CDK2	S1294	S1298Y	1298	Missense	distal	4	no	15.567	15.753	EPSD	ICGC;COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	O14686	KMT2D	P24941	CDK2	S1298	R1297H	1297	Missense	proximal	-1	no	8.882	8.431	EPSD	ICGC;COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	O14686	KMT2D	P24941	CDK2	S1298	R1299S	1299	Missense	proximal	1	no	8.882	7.414	EPSD	ICGC;COSMIC	8.148	Loss
CMGC_CDK_CDK2_CDK2_ST	O14686	KMT2D	P24941	CDK2	S1298	S1298Y	1298	Missense	central	0	yes	8.882	0.000	EPSD	ICGC;COSMIC	8.148	Loss
CMGC_CDK_CDK2_CDK2_ST	O14686	KMT2D	P24941	CDK2	S1606	M1605I	1605	Missense	proximal	-1	no	16.246	15.179	EPSD	ICGC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	O14686	KMT2D	P24941	CDK2	S1606	L1600M	1600	Missense	distal	-6	no	16.246	16.253	EPSD	ICGC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	O14686	KMT2D	P24941	CDK2	S1606	H1609Q	1609	Missense	distal	3	no	16.246	15.199	EPSD	ICGC;COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	O14686	KMT2D	P24941	CDK2	S1606	R1612C	1612	Missense	distal	6	no	16.246	16.248	EPSD	ICGC;COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	O14686	KMT2D	P24941	CDK2	S1629	E1627D	1627	Missense	proximal	-2	no	7.389	8.369	EPSD	ICGC;COSMIC	8.148	Gain
CMGC_CDK_CDK2_CDK2_ST	O14686	KMT2D	P24941	CDK2	S1671	S1671R	1671	Missense	central	0	yes	15.472	0.000	EPSD	ICGC;COSMIC	8.148	Loss
CMGC_CDK_CDK2_CDK2_ST	O14686	KMT2D	P24941	CDK2	T1803	G1802W	1802	Missense	proximal	-1	no	14.035	14.111	EPSD	ICGC;COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	O14686	KMT2D	P24941	CDK2	S1820	D1824N	1824	Missense	distal	4	no	8.337	8.381	EPSD	ICGC;COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	O14686	KMT2D	P24941	CDK2	S1820	D1825N	1825	Missense	distal	5	no	8.337	8.266	EPSD	ICGC;COSMIC;GDSC;CCLE	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	O14686	KMT2D	P24941	CDK2	S1854	P1855S	1855	Missense	proximal	1	no	15.691	4.425	EPSD	ICGC	8.148	Loss
CMGC_CDK_CDK2_CDK2_ST	O14686	KMT2D	P24941	CDK2	T1919	P1920S	1920	Missense	proximal	1	no	12.736	1.470	EPSD	ICGC	8.148	Loss
CMGC_CDK_CDK2_CDK2_ST	O14686	KMT2D	P24941	CDK2	T1919	P1920Q	1920	Missense	proximal	1	no	12.736	4.825	EPSD	ICGC	8.148	Loss
CMGC_CDK_CDK2_CDK2_ST	O14686	KMT2D	P24941	CDK2	S1939	L1935V	1935	Missense	distal	-4	no	13.700	13.710	EPSD	ICGC;COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	O14686	KMT2D	P24941	CDK2	S1950	D1954H	1954	Missense	distal	4	no	11.653	11.480	EPSD	ICGC;COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	O14686	KMT2D	P24941	CDK2	S1963	P1964S	1964	Missense	proximal	1	no	14.364	3.099	EPSD	ICGC;COSMIC	8.148	Loss
CMGC_CDK_CDK2_CDK2_ST	O14686	KMT2D	P24941	CDK2	S1963	P1969S	1969	Missense	distal	6	no	14.364	14.366	EPSD	ICGC;COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	O14686	KMT2D	P24941	CDK2	S1963	F1962Y	1962	Missense	proximal	-1	no	14.364	14.018	EPSD	ICGC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	O14686	KMT2D	P24941	CDK2	S1963	D1970G	1970	Missense	distal	7	no	14.364	14.348	EPSD	ICGC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	O14686	KMT2D	P24941	CDK2	S1963	R1958H	1958	Missense	distal	-5	no	14.364	14.365	EPSD	ICGC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	O14686	KMT2D	P24941	CDK2	S1963	G1959W	1959	Missense	distal	-4	no	14.364	13.682	EPSD	ICGC;COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	O14686	KMT2D	P24941	CDK2	S1963	G1959V	1959	Missense	distal	-4	no	14.364	14.634	EPSD	ICGC;COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	O14686	KMT2D	P24941	CDK2	S1971	P1964S	1964	Missense	distal	-7	no	14.181	14.001	EPSD	ICGC;COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	O14686	KMT2D	P24941	CDK2	S1971	T1974M	1974	Missense	distal	3	no	14.181	14.056	EPSD	ICGC;COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	O14686	KMT2D	P24941	CDK2	S1971	P1969S	1969	Missense	proximal	-2	no	14.181	13.530	EPSD	ICGC;COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	O14686	KMT2D	P24941	CDK2	S1971	D1970G	1970	Missense	proximal	-1	no	14.181	14.474	EPSD	ICGC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	O14686	KMT2D	P24941	CDK2	S1971	G1975S	1975	Missense	distal	4	no	14.181	14.315	EPSD	ICGC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	O14686	KMT2D	P24941	CDK2	T1986	P1984S	1984	Missense	proximal	-2	no	13.815	13.164	EPSD	ICGC;COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	O14686	KMT2D	P24941	CDK2	S2115	G2114D	2114	Missense	proximal	-1	no	13.355	13.062	EPSD	ICGC;COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	O14686	KMT2D	P24941	CDK2	S2115	A2119T	2119	Missense	distal	4	no	13.355	13.598	EPSD	ICGC;COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	O14686	KMT2D	P24941	CDK2	T2229	E2225G	2225	Missense	distal	-4	no	14.167	13.619	EPSD	ICGC;COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	O14686	KMT2D	P24941	CDK2	T2229	H2227Q	2227	Missense	proximal	-2	no	14.167	14.610	EPSD	ICGC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	O14686	KMT2D	P24941	CDK2	T2229	G2232C	2232	Missense	distal	3	no	14.167	9.623	EPSD	ICGC;COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	O14686	KMT2D	P24941	CDK2	T2233	H2227Q	2227	Missense	distal	-6	no	15.488	15.487	EPSD	ICGC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	O14686	KMT2D	P24941	CDK2	T2233	G2232C	2232	Missense	proximal	-1	no	15.488	14.312	EPSD	ICGC;COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	O14686	KMT2D	P24941	CDK2	T2240	P2243T	2243	Missense	distal	3	no	13.084	12.970	EPSD	ICGC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	O14686	KMT2D	P24941	CDK2	S2260	G2264V	2264	Missense	distal	4	no	14.092	14.439	EPSD	ICGC;COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	O14686	KMT2D	P24941	CDK2	S2296	P2302T	2302	Missense	distal	6	no	12.463	12.471	EPSD	ICGC;COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	O14686	KMT2D	P24941	CDK2	S2309	P2302T	2302	Missense	distal	-7	no	12.848	12.846	EPSD	ICGC;COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	O14686	KMT2D	P24941	CDK2	T2323	K2322E	2322	Missense	proximal	-1	no	14.175	15.060	EPSD	ICGC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	O14686	KMT2D	P24941	CDK2	T2323	T2323K	2323	Missense	central	0	yes	14.175	0.000	EPSD	ICGC	8.148	Loss
CMGC_CDK_CDK2_CDK2_ST	O14686	KMT2D	P24941	CDK2	T2323	A2329T	2329	Missense	distal	6	no	14.175	14.187	EPSD	ICGC;COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	O14686	KMT2D	P24941	CDK2	T2332	R2334L	2334	Missense	proximal	2	no	11.648	11.382	EPSD	ICGC;COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	O14686	KMT2D	P24941	CDK2	T2332	A2329T	2329	Missense	distal	-3	no	11.648	11.667	EPSD	ICGC;COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	O14686	KMT2D	P24941	CDK2	S2342	P2343L	2343	Missense	proximal	1	no	14.397	4.576	EPSD	ICGC;COSMIC	8.148	Loss
CMGC_CDK_CDK2_CDK2_ST	O14686	KMT2D	P24941	CDK2	S2361	A2359V	2359	Missense	proximal	-2	no	15.371	14.705	EPSD	ICGC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	O14686	KMT2D	P24941	CDK2	S2423	P2424L	2424	Missense	proximal	1	no	13.612	3.791	EPSD	ICGC	8.148	Loss
CMGC_CDK_CDK2_CDK2_ST	O14686	KMT2D	P24941	CDK2	S2423	L2430P	2430	Missense	distal	7	no	13.612	13.581	EPSD	ICGC;COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	O14686	KMT2D	P24941	CDK2	S2423	R2428Q	2428	Missense	distal	5	no	13.612	13.465	EPSD	ICGC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	O14686	KMT2D	P24941	CDK2	T2426	P2424L	2424	Missense	proximal	-2	no	11.686	11.462	EPSD	ICGC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	O14686	KMT2D	P24941	CDK2	T2426	L2430P	2430	Missense	distal	4	no	11.686	11.574	EPSD	ICGC;COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	O14686	KMT2D	P24941	CDK2	T2426	R2428Q	2428	Missense	proximal	2	no	11.686	11.586	EPSD	ICGC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	O14686	KMT2D	P24941	CDK2	S2512	V2519F	2519	Missense	distal	7	no	7.795	8.238	EPSD	ICGC;COSMIC	8.148	Gain
CMGC_CDK_CDK2_CDK2_ST	O14686	KMT2D	P24941	CDK2	S2592	P2596T	2596	Missense	distal	4	no	13.596	13.878	EPSD	ICGC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	O14686	KMT2D	P24941	CDK2	S2592	G2585A	2585	Missense	distal	-7	no	13.596	13.436	EPSD	ICGC;COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	O14686	KMT2D	P24941	CDK2	S2592	G2595W	2595	Missense	distal	3	no	13.596	12.775	EPSD	ICGC;COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	O14686	KMT2D	P24941	CDK2	S2608	P2613S	2613	Missense	distal	5	no	14.981	14.880	EPSD	ICGC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	O14686	KMT2D	P24941	CDK2	S2636	T2639N	2639	Missense	distal	3	no	9.649	9.201	EPSD	ICGC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	O14686	KMT2D	P24941	CDK2	S2636	G2631V	2631	Missense	distal	-5	no	9.649	9.600	EPSD	ICGC;COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	O14686	KMT2D	P24941	CDK2	S2640	T2639N	2639	Missense	proximal	-1	no	16.077	16.266	EPSD	ICGC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	O14686	KMT2D	P24941	CDK2	S2726	S2725R	2725	Missense	proximal	-1	no	13.529	14.571	EPSD	ICGC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	O14686	KMT2D	P24941	CDK2	S2852	R2847C	2847	Missense	distal	-5	no	15.356	15.390	EPSD	ICGC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	O14686	KMT2D	P24941	CDK2	S2852	T2859N	2859	Missense	distal	7	no	15.356	15.567	EPSD	ICGC;COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	O14686	KMT2D	P24941	CDK2	S2852	P2853Q	2853	Missense	proximal	1	no	15.356	7.445	EPSD	ICGC	8.148	Loss
CMGC_CDK_CDK2_CDK2_ST	O14686	KMT2D	P24941	CDK2	S2852	Q2848K	2848	Missense	distal	-4	no	15.356	15.494	EPSD	ICGC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	O14686	KMT2D	P24941	CDK2	T2949	P2955A	2955	Missense	distal	6	no	12.037	12.032	EPSD	ICGC;COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	O14686	KMT2D	P24941	CDK2	T2949	S2945N	2945	Missense	distal	-4	no	12.037	11.820	EPSD	ICGC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	O14686	KMT2D	P24941	CDK2	T2959	P2955A	2955	Missense	distal	-4	no	8.464	8.406	EPSD	ICGC;COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	O14686	KMT2D	P24941	CDK2	S3130	P3131L	3131	Missense	proximal	1	no	15.075	5.254	EPSD	ICGC	8.148	Loss
CMGC_CDK_CDK2_CDK2_ST	O14686	KMT2D	P24941	CDK2	T3138	P3131L	3131	Missense	distal	-7	no	12.165	12.170	EPSD	ICGC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	O14686	KMT2D	P24941	CDK2	T3138	A3144V	3144	Missense	distal	6	no	12.165	12.168	EPSD	ICGC;COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	O14686	KMT2D	P24941	CDK2	T3138	A3144S	3144	Missense	distal	6	no	12.165	12.170	EPSD	ICGC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	O14686	KMT2D	P24941	CDK2	S3478	R3482Q	3482	Missense	distal	4	no	8.737	8.918	EPSD	ICGC;COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	O14686	KMT2D	P24941	CDK2	S3478	Q3480H	3480	Missense	proximal	2	no	8.737	8.755	EPSD	ICGC;COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	O14686	KMT2D	P24941	CDK2	S3478	Q3480L	3480	Missense	proximal	2	no	8.737	8.571	EPSD	ICGC;COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	O14686	KMT2D	P24941	CDK2	S3620	R3626W	3626	Missense	distal	6	no	13.898	13.890	EPSD	ICGC;COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	O14686	KMT2D	P24941	CDK2	S3620	Q3623R	3623	Missense	distal	3	no	13.898	15.641	EPSD	ICGC;COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	O14686	KMT2D	P24941	CDK2	S3624	R3626W	3626	Missense	proximal	2	no	12.661	12.758	EPSD	ICGC;COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	O14686	KMT2D	P24941	CDK2	S3624	Q3623R	3623	Missense	proximal	-1	no	12.661	13.539	EPSD	ICGC;COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	O14686	KMT2D	P24941	CDK2	S3837	Q3839K	3839	Missense	proximal	2	no	13.020	12.820	EPSD	ICGC;COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	O14686	KMT2D	P24941	CDK2	S3986	R3982L	3982	Missense	distal	-4	no	12.479	12.664	EPSD	ICGC;COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	O14686	KMT2D	P24941	CDK2	S4011	P4012H	4012	Missense	proximal	1	no	10.269	3.510	EPSD	ICGC;COSMIC	8.148	Loss
CMGC_CDK_CDK2_CDK2_ST	O14686	KMT2D	P24941	CDK2	S4215	P4209Q	4209	Missense	distal	-6	no	12.661	12.664	EPSD	ICGC;COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	O14686	KMT2D	P24941	CDK2	S4215	L4222P	4222	Missense	distal	7	no	12.661	12.630	EPSD	ICGC;COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	O14686	KMT2D	P24941	CDK2	S4325	Q4322K	4322	Missense	distal	-3	no	14.343	14.245	EPSD	ICGC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	O14686	KMT2D	P24941	CDK2	T4343	P4338H	4338	Missense	distal	-5	no	13.746	13.793	EPSD	ICGC;COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	O14686	KMT2D	P24941	CDK2	T4343	Q4347K	4347	Missense	distal	4	no	13.746	14.086	EPSD	ICGC;COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	O14686	KMT2D	P24941	CDK2	T4343	G4348V	4348	Missense	distal	5	no	13.746	13.586	EPSD	ICGC;COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	O14686	KMT2D	P24941	CDK2	S4359	A4363S	4363	Missense	distal	4	no	11.461	11.434	EPSD	ICGC;COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	O14686	KMT2D	P24941	CDK2	T4505	G4504C	4504	Missense	proximal	-1	no	14.516	13.341	EPSD	ICGC;COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	O14686	KMT2D	P24941	CDK2	T4505	E4510K	4510	Missense	distal	5	no	14.516	14.383	EPSD	ICGC;COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	O14686	KMT2D	P24941	CDK2	T4505	P4506T	4506	Missense	proximal	1	no	14.516	4.559	EPSD	ICGC;COSMIC	8.148	Loss
CMGC_CDK_CDK2_CDK2_ST	O14686	KMT2D	P24941	CDK2	T4519	R4524W	4524	Missense	distal	5	no	13.314	13.481	EPSD	ICGC;COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	O14686	KMT2D	P24941	CDK2	T4643	V4639A	4639	Missense	distal	-4	no	13.882	13.871	EPSD	ICGC;COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	O14686	KMT2D	P24941	CDK2	T4682	A4679V	4679	Missense	distal	-3	no	15.577	15.778	EPSD	ICGC;COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	O14686	KMT2D	P24941	CDK2	T4682	D4675E	4675	Missense	distal	-7	no	15.577	15.426	EPSD	ICGC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	O14686	KMT2D	P24941	CDK2	S4710	G4716W	4716	Missense	distal	6	no	13.178	13.165	EPSD	ICGC;COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	O14686	KMT2D	P24941	CDK2	S4710	S4713N	4713	Missense	distal	3	no	13.178	12.581	EPSD	ICGC;COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	O14686	KMT2D	P24941	CDK2	S4738	E4733K	4733	Missense	distal	-5	no	14.964	14.929	EPSD	ICGC;COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	O14686	KMT2D	P24941	CDK2	S4738	I4741V	4741	Missense	distal	3	no	14.964	16.240	EPSD	ICGC;COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	O14686	KMT2D	P24941	CDK2	S4738	P4739S	4739	Missense	proximal	1	no	14.964	3.698	EPSD	ICGC;COSMIC;GDSC;CCLE	8.148	Loss
CMGC_CDK_CDK2_CDK2_ST	O14686	KMT2D	P24941	CDK2	S4822	F4819L	4819	Missense	distal	-3	no	15.361	15.103	EPSD	ICGC;COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	O14686	KMT2D	P24941	CDK2	S4849	P4850T	4850	Missense	proximal	1	no	13.011	3.054	EPSD	ICGC;COSMIC	8.148	Loss
CMGC_CDK_CDK2_CDK2_ST	O14686	KMT2D	P24941	CDK2	S4849	P4850Q	4850	Missense	proximal	1	no	13.011	5.099	EPSD	ICGC;COSMIC	8.148	Loss
CMGC_CDK_CDK2_CDK2_ST	O14686	KMT2D	P24941	CDK2	S4871	D4874H	4874	Missense	distal	3	no	5.333	8.169	EPSD	ICGC	8.148	Gain
CMGC_CDK_CDK2_CDK2_ST	O14686	KMT2D	P24941	CDK2	S4883	S4883R	4883	Missense	central	0	yes	15.576	0.000	EPSD	ICGC	8.148	Loss
CMGC_CDK_CDK2_CDK2_ST	O14686	KMT2D	P24941	CDK2	S4883	P4886L	4886	Missense	distal	3	no	15.576	15.192	EPSD	ICGC;COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	O14686	KMT2D	P24941	CDK2	S4955	A4953D	4953	Missense	proximal	-2	no	13.119	12.968	EPSD	ICGC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	O14686	KMT2D	P24941	CDK2	T5347	H5348N	5348	Missense	proximal	1	no	11.255	-22.598	EPSD	ICGC	8.148	Loss
CMGC_CDK_CDK2_CDK2_ST	O14686	KMT2D	P24941	CDK2	T5374	F5380L	5380	Missense	distal	6	no	15.651	15.670	PhosphoSitePlus	ICGC;COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	O14686	KMT2D	P24941	CDK2	T5374	P5375T	5375	Missense	proximal	1	no	15.651	5.693	PhosphoSitePlus	ICGC	8.148	Loss
CMGC_CDK_CDK2_CDK2_ST	O14686	KMT2D	P24941	CDK2	T5374	N5373K	5373	Missense	proximal	-1	no	15.651	15.624	PhosphoSitePlus	ICGC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	O14686	KMT2D	P24941	CDK2	T5374	Q5379K	5379	Missense	distal	5	no	15.651	15.636	PhosphoSitePlus	ICGC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	O14686	KMT2D	P24941	CDK2	T5374	T5372N	5372	Missense	proximal	-2	no	15.651	14.341	PhosphoSitePlus	ICGC;COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	P29590	PML	P24941	CDK2	S221	A216V	216	Missense	distal	-5	no	8.287	8.293	EPSD	ICGC;COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	P29590	PML	P24941	CDK2	S221	S220C	220	Missense	proximal	-1	no	8.287	8.630	EPSD	ICGC;COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	P29590	PML	P24941	CDK2	S221	S214L	214	Missense	distal	-7	no	8.287	8.472	EPSD	ICGC;COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	P29590	PML	P24941	CDK2	T391	V398L	398	Missense	distal	7	no	9.259	9.031	EPSD	ICGC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	P29590	PML	P24941	CDK2	T391	S388Y	388	Missense	distal	-3	no	9.259	9.278	EPSD	ICGC;COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	P29590	PML	P24941	CDK2	T391	C389R	389	Missense	proximal	-2	no	9.259	9.084	EPSD	ICGC;COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	P29590	PML	P24941	CDK2	T391	S388F	388	Missense	distal	-3	no	9.259	9.350	EPSD	ICGC;COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	P29590	PML	P24941	CDK2	S403	P410A	410	Missense	distal	7	no	15.136	15.521	EPSD	ICGC;COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	P29590	PML	P24941	CDK2	S403	V398L	398	Missense	distal	-5	no	15.136	15.117	EPSD	ICGC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	P29590	PML	P24941	CDK2	S403	A407S	407	Missense	distal	4	no	15.136	15.110	EPSD	ICGC;COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	P29590	PML	P24941	CDK2	S403	A407T	407	Missense	distal	4	no	15.136	15.379	EPSD	ICGC;COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	P29590	PML	P24941	CDK2	T409	P410A	410	Missense	proximal	1	no	12.973	-1.430	EPSD	ICGC;COSMIC	8.148	Loss
CMGC_CDK_CDK2_CDK2_ST	P29590	PML	P24941	CDK2	T409	A407S	407	Missense	proximal	-2	no	12.973	12.306	EPSD	ICGC;COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	P29590	PML	P24941	CDK2	T409	A407T	407	Missense	proximal	-2	no	12.973	12.924	EPSD	ICGC;COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	P29590	PML	P24941	CDK2	S505	Q508H	508	Missense	distal	3	no	11.013	12.060	EPSD	ICGC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	P29590	PML	P24941	CDK2	S505	S505F	505	Missense	central	0	yes	11.013	0.000	EPSD	ICGC	8.148	Loss
CMGC_CDK_CDK2_CDK2_ST	P29590	PML	P24941	CDK2	S518	P525L	525	Missense	distal	7	no	16.502	16.532	PhosphoSitePlus	ICGC;COSMIC;GDSC;CCLE	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	P29590	PML	P24941	CDK2	S527	P525L	525	Missense	proximal	-2	no	15.309	15.085	EPSD	ICGC;COSMIC;GDSC;CCLE	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	P29590	PML	P24941	CDK2	S527	P526L	526	Missense	proximal	-1	no	15.309	15.130	EPSD	ICGC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	P29590	PML	P24941	CDK2	S530	P525L	525	Missense	distal	-5	no	14.428	14.440	EPSD	ICGC;COSMIC;GDSC;CCLE	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	P29590	PML	P24941	CDK2	S530	S535L	535	Missense	distal	5	no	14.428	14.569	EPSD	ICGC;COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	P29590	PML	P24941	CDK2	S530	P526L	526	Missense	distal	-4	no	14.428	14.370	EPSD	ICGC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	P29590	PML	P24941	CDK2	T592	L593P	593	Missense	proximal	1	no	5.613	15.434	EPSD	ICGC	8.148	Gain
CMGC_CDK_CDK2_CDK2_ST	P29590	PML	P24941	CDK2	T867	R861W	861	Missense	distal	-6	no	12.361	12.367	EPSD	ICGC;COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	P29590	PML	P24941	CDK2	T867	P868T	868	Missense	proximal	1	no	12.361	2.404	EPSD	ICGC	8.148	Loss
CMGC_CDK_CDK2_CDK2_ST	P29590	PML	P24941	CDK2	T867	P868S	868	Missense	proximal	1	no	12.361	1.095	EPSD	ICGC	8.148	Loss
CMGC_CDK_CDK2_CDK2_ST	P29590	PML	P24941	CDK2	T867	G873C	873	Missense	distal	6	no	12.361	12.359	EPSD	ICGC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	Q13242	SRSF9	P24941	CDK2	S109	R108T	108	Missense	proximal	-1	no	9.381	8.547	EPSD	ICGC;COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	Q13242	SRSF9	P24941	CDK2	S109	G103W	103	Missense	distal	-6	no	9.381	9.386	EPSD	ICGC;COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	Q05682	CALD1	P24941	CDK2	S248	G247D	247	Missense	proximal	-1	no	8.295	8.002	EPSD	ICGC;COSMIC	8.148	Loss
CMGC_CDK_CDK2_CDK2_ST	Q05682	CALD1	P24941	CDK2	S248	H253N	253	Missense	distal	5	no	8.295	8.320	EPSD	ICGC;COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	Q05682	CALD1	P24941	CDK2	S252	G247D	247	Missense	distal	-5	no	8.892	8.870	EPSD	ICGC;COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	Q05682	CALD1	P24941	CDK2	S252	H253N	253	Missense	proximal	1	no	8.892	-24.961	EPSD	ICGC;COSMIC	8.148	Loss
CMGC_CDK_CDK2_CDK2_ST	P49916	LIG3	P24941	CDK2	S210	A215S	215	Missense	distal	5	no	16.775	16.664	EPSD;PhosphoSitePlus	ICGC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	P49916	LIG3	P24941	CDK2	S210	G206V	206	Missense	distal	-4	no	16.775	17.045	EPSD;PhosphoSitePlus	ICGC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	P49916	LIG3	P24941	CDK2	S210	A215V	215	Missense	distal	5	no	16.775	16.732	EPSD;PhosphoSitePlus	ICGC;COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	P49916	LIG3	P24941	CDK2	S242	S242G	242	Missense	central	0	yes	11.280	0.000	EPSD	ICGC;COSMIC	8.148	Loss
CMGC_CDK_CDK2_CDK2_ST	P49916	LIG3	P24941	CDK2	T244	S242G	242	Missense	proximal	-2	no	14.796	14.705	EPSD	ICGC;COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	P49916	LIG3	P24941	CDK2	S913	A909S	909	Missense	distal	-4	no	17.288	17.701	EPSD;PhosphoSitePlus	ICGC;COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	P49916	LIG3	P24941	CDK2	S913	K920R	920	Missense	distal	7	no	17.288	18.064	EPSD;PhosphoSitePlus	ICGC;COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	P49916	LIG3	P24941	CDK2	S913	P914T	914	Missense	proximal	1	no	17.288	7.331	EPSD;PhosphoSitePlus	ICGC;COSMIC	8.148	Loss
CMGC_CDK_CDK2_CDK2_ST	P49916	LIG3	P24941	CDK2	S913	P914Q	914	Missense	proximal	1	no	17.288	9.376	EPSD;PhosphoSitePlus	ICGC;COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	P49916	LIG3	P24941	CDK2	S913	G918R	918	Missense	distal	5	no	17.288	17.268	EPSD;PhosphoSitePlus	ICGC;COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	P48634	PRRC2A	P24941	CDK2	T132	V139I	139	Missense	distal	7	no	14.276	14.075	EPSD	ICGC;COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	P48634	PRRC2A	P24941	CDK2	T132	P136S	136	Missense	distal	4	no	14.276	14.290	EPSD	ICGC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	P48634	PRRC2A	P24941	CDK2	T132	G138R	138	Missense	distal	6	no	14.276	14.271	EPSD	ICGC;COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	P48634	PRRC2A	P24941	CDK2	S365	R369Q	369	Missense	distal	4	no	8.825	9.006	EPSD	ICGC;COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	P48634	PRRC2A	P24941	CDK2	T610	P614L	614	Missense	distal	4	no	12.989	13.101	EPSD	ICGC;COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	P48634	PRRC2A	P24941	CDK2	T610	E604D	604	Missense	distal	-6	no	12.989	12.985	EPSD	ICGC;COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	P48634	PRRC2A	P24941	CDK2	T782	R780W	780	Missense	proximal	-2	no	13.246	12.747	EPSD	ICGC;COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	P48634	PRRC2A	P24941	CDK2	T799	R804C	804	Missense	distal	5	no	14.750	14.877	EPSD	ICGC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	P48634	PRRC2A	P24941	CDK2	T799	T799A	799	Missense	central	0	yes	14.750	0.000	EPSD	ICGC	8.148	Loss
CMGC_CDK_CDK2_CDK2_ST	P48634	PRRC2A	P24941	CDK2	S808	R804C	804	Missense	distal	-4	no	16.000	15.491	EPSD	ICGC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	P48634	PRRC2A	P24941	CDK2	T825	P826A	826	Missense	proximal	1	no	15.990	1.587	EPSD	ICGC;COSMIC	8.148	Loss
CMGC_CDK_CDK2_CDK2_ST	P48634	PRRC2A	P24941	CDK2	T878	E872K	872	Missense	distal	-6	no	15.249	15.246	EPSD	ICGC;COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	P48634	PRRC2A	P24941	CDK2	T975	P978T	978	Missense	distal	3	no	13.110	12.996	EPSD	ICGC;COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	P48634	PRRC2A	P24941	CDK2	T975	E974Q	974	Missense	proximal	-1	no	13.110	12.018	EPSD	ICGC;COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	P48634	PRRC2A	P24941	CDK2	T997	S1004F	1004	Missense	distal	7	no	12.624	13.477	EPSD	ICGC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	P48634	PRRC2A	P24941	CDK2	T997	N1002D	1002	Missense	distal	5	no	12.624	12.695	EPSD	ICGC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	P48634	PRRC2A	P24941	CDK2	S1004	P1007T	1007	Missense	distal	3	no	15.107	14.993	EPSD	ICGC;COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	P48634	PRRC2A	P24941	CDK2	S1004	S1004F	1004	Missense	central	0	yes	15.107	0.000	EPSD	ICGC	8.148	Loss
CMGC_CDK_CDK2_CDK2_ST	P48634	PRRC2A	P24941	CDK2	S1004	N1002D	1002	Missense	proximal	-2	no	15.107	16.315	EPSD	ICGC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	P48634	PRRC2A	P24941	CDK2	S1004	R1011S	1011	Missense	distal	7	no	15.107	14.465	EPSD	ICGC;COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	P48634	PRRC2A	P24941	CDK2	T1108	R1104W	1104	Missense	distal	-4	no	9.643	8.885	EPSD	ICGC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	P48634	PRRC2A	P24941	CDK2	S1219	P1220S	1220	Missense	proximal	1	no	14.344	3.078	EPSD	ICGC;COSMIC	8.148	Loss
CMGC_CDK_CDK2_CDK2_ST	P48634	PRRC2A	P24941	CDK2	S1219	R1223H	1223	Missense	distal	4	no	14.344	14.226	EPSD	ICGC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	P48634	PRRC2A	P24941	CDK2	S1219	S1219P	1219	Missense	central	0	yes	14.344	0.000	EPSD	ICGC	8.148	Loss
CMGC_CDK_CDK2_CDK2_ST	P48634	PRRC2A	P24941	CDK2	S1306	R1300H	1300	Missense	distal	-6	no	14.241	14.243	EPSD	ICGC;COSMIC;GDSC;CCLE	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	P48634	PRRC2A	P24941	CDK2	S1554	R1561W	1561	Missense	distal	7	no	12.805	13.204	EPSD	ICGC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	P48634	PRRC2A	P24941	CDK2	S1554	G1552R	1552	Missense	proximal	-2	no	12.805	12.311	EPSD	ICGC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	P48634	PRRC2A	P24941	CDK2	S1554	R1548W	1548	Missense	distal	-6	no	12.805	12.811	EPSD	ICGC;COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	P48634	PRRC2A	P24941	CDK2	S1554	P1558S	1558	Missense	distal	4	no	12.805	12.818	EPSD	ICGC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	P48634	PRRC2A	P24941	CDK2	S1671	G1664D	1664	Missense	distal	-7	no	12.291	12.208	EPSD	ICGC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	P48634	PRRC2A	P24941	CDK2	S1691	A1695D	1695	Missense	distal	4	no	10.207	10.102	EPSD	ICGC;COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	P48634	PRRC2A	P24941	CDK2	S1691	R1686M	1686	Missense	distal	-5	no	10.207	10.267	EPSD	ICGC;COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	P48634	PRRC2A	P24941	CDK2	S1691	P1687L	1687	Missense	distal	-4	no	10.207	10.149	EPSD	ICGC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	P48634	PRRC2A	P24941	CDK2	S1691	P1697H	1697	Missense	distal	6	no	10.207	10.202	EPSD	ICGC;COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	P48634	PRRC2A	P24941	CDK2	T1868	R1865C	1865	Missense	distal	-3	no	14.167	14.082	EPSD	ICGC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	P48634	PRRC2A	P24941	CDK2	T1868	P1866H	1866	Missense	proximal	-2	no	14.167	13.157	EPSD	ICGC;COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	P48634	PRRC2A	P24941	CDK2	T2076	R2075W	2075	Missense	proximal	-1	no	15.123	15.678	EPSD	ICGC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	P48634	PRRC2A	P24941	CDK2	T2093	T2093M	2093	Missense	central	0	yes	13.815	0.000	EPSD	ICGC	8.148	Loss
CMGC_CDK_CDK2_CDK2_ST	P48634	PRRC2A	P24941	CDK2	S2098	T2093M	2093	Missense	distal	-5	no	9.042	9.150	EPSD	ICGC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	P48634	PRRC2A	P24941	CDK2	S2098	R2102H	2102	Missense	distal	4	no	9.042	8.925	EPSD	ICGC;GDSC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	P48634	PRRC2A	P24941	CDK2	S2113	V2106I	2106	Missense	distal	-7	no	12.104	12.279	EPSD	ICGC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	P48634	PRRC2A	P24941	CDK2	S2113	Q2110P	2110	Missense	distal	-3	no	12.104	12.046	EPSD	ICGC;COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	P20248	CCNA2	P24941	CDK2	S154	M160I	160	Missense	distal	6	no	12.572	12.591	PhosphoSitePlus	ICGC;COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	P20248	CCNA2	P24941	CDK2	S154	P147T	147	Missense	distal	-7	no	12.572	12.569	PhosphoSitePlus	ICGC;COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	P20248	CCNA2	P24941	CDK2	S375	S371R	371	Missense	distal	-4	no	8.302	7.704	EPSD	ICGC;COSMIC	8.148	Loss
CMGC_CDK_CDK2_CDK2_ST	P20248	CCNA2	P24941	CDK2	S375	T368K	368	Missense	distal	-7	no	8.302	8.257	EPSD	ICGC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	P20248	CCNA2	P24941	CDK2	S375	W372L	372	Missense	distal	-3	no	8.302	7.961	EPSD	ICGC;COSMIC	8.148	Loss
CMGC_CDK_CDK2_CDK2_ST	O95251	KAT7	P24941	CDK2	S57	Q51E	51	Missense	distal	-6	no	15.082	15.081	EPSD	ICGC;COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	O95251	KAT7	P24941	CDK2	S57	R60L	60	Missense	distal	3	no	15.082	12.980	EPSD	ICGC;COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	O95251	KAT7	P24941	CDK2	S57	P58L	58	Missense	proximal	1	no	15.082	5.261	EPSD	ICGC	8.148	Loss
CMGC_CDK_CDK2_CDK2_ST	O95251	KAT7	P24941	CDK2	S57	V59I	59	Missense	proximal	2	no	15.082	14.936	EPSD	ICGC;COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	O95251	KAT7	P24941	CDK2	T85	R79H	79	Missense	distal	-6	no	13.330	13.331	EPSD	ICGC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	O95251	KAT7	P24941	CDK2	T85	P86S	86	Missense	proximal	1	no	13.330	2.064	EPSD	ICGC	8.148	Loss
CMGC_CDK_CDK2_CDK2_ST	O95251	KAT7	P24941	CDK2	T88	R95L	95	Missense	distal	7	no	16.778	16.319	PhosphoSitePlus	ICGC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	O95251	KAT7	P24941	CDK2	T88	P86S	86	Missense	proximal	-2	no	16.778	16.127	PhosphoSitePlus	ICGC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	O95251	KAT7	P24941	CDK2	S124	D122G	122	Missense	proximal	-2	no	21.068	20.460	EPSD	ICGC;COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	O95251	KAT7	P24941	CDK2	S124	T118A	118	Missense	distal	-6	no	21.068	21.067	EPSD	ICGC;GDSC;CCLE	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	O95251	KAT7	P24941	CDK2	T128	D122G	122	Missense	distal	-6	no	14.686	14.690	EPSD	ICGC;COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	O95251	KAT7	P24941	CDK2	T128	A133V	133	Missense	distal	5	no	14.686	14.643	EPSD	ICGC;COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	O95251	KAT7	P24941	CDK2	S144	D141N	141	Missense	distal	-3	no	15.147	15.103	EPSD	ICGC;COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	O95251	KAT7	P24941	CDK2	S144	V147L	147	Missense	distal	3	no	15.147	14.155	EPSD	ICGC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	O95251	KAT7	P24941	CDK2	S144	S148Y	148	Missense	distal	4	no	15.147	15.333	EPSD	ICGC;COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	O95251	KAT7	P24941	CDK2	S148	D141N	141	Missense	distal	-7	no	10.590	10.267	EPSD	ICGC;COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	O95251	KAT7	P24941	CDK2	S148	V147L	147	Missense	proximal	-1	no	10.590	10.453	EPSD	ICGC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	O95251	KAT7	P24941	CDK2	S148	S148Y	148	Missense	central	0	yes	10.590	0.000	EPSD	ICGC;COSMIC	8.148	Loss
CMGC_CDK_CDK2_CDK2_ST	O95251	KAT7	P24941	CDK2	T187	G189D	189	Missense	proximal	2	no	8.322	8.201	EPSD	ICGC;COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	O95251	KAT7	P24941	CDK2	T187	F181C	181	Missense	distal	-6	no	8.322	8.323	EPSD	ICGC;COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	O95251	KAT7	P24941	CDK2	S506	E508D	508	Missense	proximal	2	no	17.327	17.227	EPSD	ICGC;COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	O15014	ZNF609	P24941	CDK2	S8	V13L	13	Missense	distal	5	no	8.358	8.431	EPSD	ICGC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	O15014	ZNF609	P24941	CDK2	S52	S54P	54	Missense	proximal	2	no	8.368	8.302	EPSD	ICGC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	O15014	ZNF609	P24941	CDK2	S52	G53V	53	Missense	proximal	1	no	8.368	-1.231	EPSD	ICGC	8.148	Loss
CMGC_CDK_CDK2_CDK2_ST	O15014	ZNF609	P24941	CDK2	S52	Q47E	47	Missense	distal	-5	no	8.368	8.405	EPSD	ICGC;COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	O15014	ZNF609	P24941	CDK2	T76	K73N	73	Missense	distal	-3	no	12.373	12.434	EPSD	ICGC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	O15014	ZNF609	P24941	CDK2	T103	L108M	108	Missense	distal	5	no	12.980	13.247	EPSD	ICGC;COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	O15014	ZNF609	P24941	CDK2	T103	T106I	106	Missense	distal	3	no	12.980	12.426	EPSD	ICGC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	O15014	ZNF609	P24941	CDK2	T110	L108M	108	Missense	proximal	-2	no	14.818	12.958	EPSD	ICGC;COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	O15014	ZNF609	P24941	CDK2	T110	T106I	106	Missense	distal	-4	no	14.818	14.501	EPSD	ICGC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	O15014	ZNF609	P24941	CDK2	T110	A115T	115	Missense	distal	5	no	14.818	14.783	EPSD	ICGC;COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	O15014	ZNF609	P24941	CDK2	T110	P111Q	111	Missense	proximal	1	no	14.818	6.907	EPSD	ICGC;COSMIC	8.148	Loss
CMGC_CDK_CDK2_CDK2_ST	O15014	ZNF609	P24941	CDK2	S252	M250V	250	Missense	proximal	-2	no	11.772	13.206	EPSD	ICGC;COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	O15014	ZNF609	P24941	CDK2	T256	P261S	261	Missense	distal	5	no	15.112	15.011	EPSD	ICGC;COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	O15014	ZNF609	P24941	CDK2	T256	M250V	250	Missense	distal	-6	no	15.112	15.106	EPSD	ICGC;COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	O15014	ZNF609	P24941	CDK2	T256	I262V	262	Missense	distal	6	no	15.112	15.110	EPSD	ICGC;COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	O15014	ZNF609	P24941	CDK2	S275	N271S	271	Missense	distal	-4	no	12.468	12.684	EPSD	ICGC;COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	O15014	ZNF609	P24941	CDK2	S275	C277F	277	Missense	proximal	2	no	12.468	12.573	EPSD	ICGC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	O15014	ZNF609	P24941	CDK2	S275	V282A	282	Missense	distal	7	no	12.468	12.594	EPSD	ICGC;COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	O15014	ZNF609	P24941	CDK2	S358	D362Y	362	Missense	distal	4	no	12.272	12.537	EPSD	ICGC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	O15014	ZNF609	P24941	CDK2	S358	C356F	356	Missense	proximal	-2	no	12.272	12.221	EPSD	ICGC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	O15014	ZNF609	P24941	CDK2	T381	A387D	387	Missense	distal	6	no	10.192	10.181	EPSD	ICGC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	O15014	ZNF609	P24941	CDK2	S390	A387D	387	Missense	distal	-3	no	8.528	8.651	EPSD	ICGC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	O15014	ZNF609	P24941	CDK2	S390	A389T	389	Missense	proximal	-1	no	8.528	8.535	EPSD	ICGC;COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	O15014	ZNF609	P24941	CDK2	S433	S433I	433	Missense	central	0	yes	13.262	0.000	EPSD	ICGC	8.148	Loss
CMGC_CDK_CDK2_CDK2_ST	O15014	ZNF609	P24941	CDK2	S491	V493I	493	Missense	proximal	2	no	12.135	11.989	EPSD	ICGC;COSMIC;CCLE	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	O15014	ZNF609	P24941	CDK2	S609	S614L	614	Missense	distal	5	no	8.370	8.511	EPSD	ICGC;COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	O15014	ZNF609	P24941	CDK2	S609	M616V	616	Missense	distal	7	no	8.370	8.084	EPSD	ICGC	8.148	Loss
CMGC_CDK_CDK2_CDK2_ST	O15014	ZNF609	P24941	CDK2	T673	A674P	674	Missense	proximal	1	no	-2.179	12.224	EPSD	ICGC;COSMIC	8.148	Gain
CMGC_CDK_CDK2_CDK2_ST	O15014	ZNF609	P24941	CDK2	S680	A674P	674	Missense	distal	-6	no	12.267	12.269	EPSD	ICGC;COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	O15014	ZNF609	P24941	CDK2	S680	P681L	681	Missense	proximal	1	no	12.267	2.446	EPSD	ICGC;COSMIC	8.148	Loss
CMGC_CDK_CDK2_CDK2_ST	O15014	ZNF609	P24941	CDK2	S698	L701F	701	Missense	distal	3	no	14.022	14.364	EPSD	ICGC;COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	O15014	ZNF609	P24941	CDK2	S698	M695I	695	Missense	distal	-3	no	14.022	13.673	EPSD	ICGC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	O15014	ZNF609	P24941	CDK2	S804	T799M	799	Missense	distal	-5	no	13.908	14.016	EPSD	ICGC;COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	O15014	ZNF609	P24941	CDK2	T823	V827L	827	Missense	distal	4	no	16.245	16.130	EPSD	ICGC;COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	O15014	ZNF609	P24941	CDK2	S889	Q885E	885	Missense	distal	-4	no	12.960	13.409	EPSD	ICGC;COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	O15014	ZNF609	P24941	CDK2	S889	E896K	896	Missense	distal	7	no	12.960	12.629	EPSD	ICGC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	O15014	ZNF609	P24941	CDK2	S889	P884L	884	Missense	distal	-5	no	12.960	12.972	EPSD	ICGC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	O15014	ZNF609	P24941	CDK2	S900	E896K	896	Missense	distal	-4	no	12.389	12.078	EPSD	ICGC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	O15014	ZNF609	P24941	CDK2	S907	P913S	913	Missense	distal	6	no	11.560	11.561	EPSD	ICGC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	O15014	ZNF609	P24941	CDK2	S1105	K1100R	1100	Missense	distal	-5	no	8.500	8.544	EPSD	ICGC;COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	O15014	ZNF609	P24941	CDK2	S1267	K1272R	1272	Missense	distal	5	no	13.626	13.787	EPSD	ICGC;COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	O15014	ZNF609	P24941	CDK2	S1285	A1279P	1279	Missense	distal	-6	no	13.880	13.882	EPSD	ICGC;COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	O15014	ZNF609	P24941	CDK2	S1313	H1308Q	1308	Missense	distal	-5	no	13.990	13.943	EPSD	ICGC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	O15014	ZNF609	P24941	CDK2	S1313	S1317N	1317	Missense	distal	4	no	13.990	13.956	EPSD	ICGC;COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	O15014	ZNF609	P24941	CDK2	S1313	S1311I	1311	Missense	proximal	-2	no	13.990	14.487	EPSD	ICGC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	O15014	ZNF609	P24941	CDK2	S1357	P1358S	1358	Missense	proximal	1	no	12.275	1.009	EPSD	ICGC	8.148	Loss
CMGC_CDK_CDK2_CDK2_ST	O15014	ZNF609	P24941	CDK2	S1357	P1358L	1358	Missense	proximal	1	no	12.275	2.454	EPSD	ICGC	8.148	Loss
CMGC_CDK_CDK2_CDK2_ST	P17706	PTPN2	P24941	CDK2	S52	P53Q	53	Missense	proximal	1	no	12.359	4.447	EPSD	ICGC;COSMIC	8.148	Loss
CMGC_CDK_CDK2_CDK2_ST	P17706	PTPN2	P24941	CDK2	S52	Y48H	48	Missense	distal	-4	no	12.359	11.290	EPSD	ICGC;COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	P17706	PTPN2	P24941	CDK2	T261	L258F	258	Missense	distal	-3	no	11.726	11.983	EPSD	ICGC;COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	P17706	PTPN2	P24941	CDK2	T261	T261N	261	Missense	central	0	yes	11.726	0.000	EPSD	ICGC;COSMIC	8.148	Loss
CMGC_CDK_CDK2_CDK2_ST	P17706	PTPN2	P24941	CDK2	S304	M309I	309	Missense	distal	5	no	19.445	19.230	PhosphoSitePlus	ICGC;COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	P17706	PTPN2	P24941	CDK2	S304	M309V	309	Missense	distal	5	no	19.445	19.105	PhosphoSitePlus	ICGC;COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	Q9Y3Z3	SAMHD1	P24941	CDK2	S18	S18R	18	Missense	central	0	yes	13.904	0.000	EPSD	ICGC;COSMIC	8.148	Loss
CMGC_CDK_CDK2_CDK2_ST	Q9Y3Z3	SAMHD1	P24941	CDK2	T21	S18R	18	Missense	distal	-3	no	14.942	15.036	EPSD	ICGC;COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	Q9Y3Z3	SAMHD1	P24941	CDK2	T25	S18R	18	Missense	distal	-7	no	13.338	13.861	EPSD	ICGC;COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	Q9Y3Z3	SAMHD1	P24941	CDK2	T25	D31E	31	Missense	distal	6	no	13.338	13.350	EPSD	ICGC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	Q9Y3Z3	SAMHD1	P24941	CDK2	S33	D31E	31	Missense	proximal	-2	no	14.172	13.191	EPSD	ICGC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	Q9Y3Z3	SAMHD1	P24941	CDK2	T138	R145Q	145	Missense	distal	7	no	15.462	14.818	EPSD	ICGC;COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	Q9Y3Z3	SAMHD1	P24941	CDK2	T138	R143H	143	Missense	distal	5	no	15.462	15.434	EPSD	ICGC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	Q9Y3Z3	SAMHD1	P24941	CDK2	T592	D585Y	585	Missense	distal	-7	no	17.916	17.800	PhosphoSitePlus	ICGC;COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	Q9Y3Z3	SAMHD1	P24941	CDK2	T592	E597K	597	Missense	distal	5	no	17.916	17.783	PhosphoSitePlus	ICGC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	O14497	ARID1A	P24941	CDK2	S90	G95C	95	Missense	distal	5	no	9.220	9.328	EPSD	ICGC;COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	O14497	ARID1A	P24941	CDK2	S90	S90G	90	Missense	central	0	yes	9.220	0.000	EPSD	ICGC;COSMIC	8.148	Loss
CMGC_CDK_CDK2_CDK2_ST	O14497	ARID1A	P24941	CDK2	S233	G237V	237	Missense	distal	4	no	13.642	13.988	EPSD	ICGC;COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	O14497	ARID1A	P24941	CDK2	T238	G237V	237	Missense	proximal	-1	no	12.964	11.872	EPSD	ICGC;COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	O14497	ARID1A	P24941	CDK2	T286	G284V	284	Missense	proximal	-2	no	14.583	14.676	EPSD	ICGC;COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	O14497	ARID1A	P24941	CDK2	S301	Y308H	308	Missense	distal	7	no	15.027	14.889	EPSD	ICGC;COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	O14497	ARID1A	P24941	CDK2	S317	Y316F	316	Missense	proximal	-1	no	8.926	9.273	EPSD	ICGC;COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	O14497	ARID1A	P24941	CDK2	S317	P320L	320	Missense	distal	3	no	8.926	8.543	EPSD	ICGC;COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	O14497	ARID1A	P24941	CDK2	S382	D385Y	385	Missense	distal	3	no	12.096	13.164	EPSD	ICGC;COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	O14497	ARID1A	P24941	CDK2	S682	T685P	685	Missense	distal	3	no	11.289	11.403	EPSD	ICGC;GDSC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	O14497	ARID1A	P24941	CDK2	S682	P687S	687	Missense	distal	5	no	11.289	11.188	EPSD	ICGC;COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	O14497	ARID1A	P24941	CDK2	S696	R693L	693	Missense	distal	-3	no	13.124	12.864	EPSD	ICGC;COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	O14497	ARID1A	P24941	CDK2	S698	A704S	704	Missense	distal	6	no	11.860	11.866	EPSD	ICGC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	O14497	ARID1A	P24941	CDK2	S698	R693L	693	Missense	distal	-5	no	11.860	11.825	EPSD	ICGC;COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	O14497	ARID1A	P24941	CDK2	S702	A704S	704	Missense	proximal	2	no	13.388	13.430	EPSD	ICGC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	O14497	ARID1A	P24941	CDK2	S964	A959E	959	Missense	distal	-5	no	14.072	14.084	EPSD	ICGC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	O14497	ARID1A	P24941	CDK2	S964	M967V	967	Missense	distal	3	no	14.072	14.920	EPSD	ICGC;COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	O14497	ARID1A	P24941	CDK2	S964	P965Q	965	Missense	proximal	1	no	14.072	6.160	EPSD	ICGC;COSMIC	8.148	Loss
CMGC_CDK_CDK2_CDK2_ST	O14497	ARID1A	P24941	CDK2	S1126	K1125T	1125	Missense	proximal	-1	no	10.976	10.813	EPSD	ICGC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	O14497	ARID1A	P24941	CDK2	S1126	K1129N	1129	Missense	distal	3	no	10.976	7.706	EPSD	ICGC;COSMIC	8.148	Loss
CMGC_CDK_CDK2_CDK2_ST	O14497	ARID1A	P24941	CDK2	S1134	K1129N	1129	Missense	distal	-5	no	14.090	14.106	EPSD	ICGC;COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	O14497	ARID1A	P24941	CDK2	S1134	G1139V	1139	Missense	distal	5	no	14.090	13.930	EPSD	ICGC;COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	O14497	ARID1A	P24941	CDK2	S1138	G1139V	1139	Missense	proximal	1	no	8.788	-0.811	EPSD	ICGC;COSMIC	8.148	Loss
CMGC_CDK_CDK2_CDK2_ST	O14497	ARID1A	P24941	CDK2	T1146	G1139V	1139	Missense	distal	-7	no	13.026	12.722	EPSD	ICGC;COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	O14497	ARID1A	P24941	CDK2	T1164	P1165Q	1165	Missense	proximal	1	no	14.470	6.558	EPSD	ICGC;COSMIC	8.148	Loss
CMGC_CDK_CDK2_CDK2_ST	O14497	ARID1A	P24941	CDK2	T1168	P1165Q	1165	Missense	distal	-3	no	13.398	13.456	EPSD	ICGC;COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	O14497	ARID1A	P24941	CDK2	S1171	P1165Q	1165	Missense	distal	-6	no	8.460	8.462	EPSD	ICGC;COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	O14497	ARID1A	P24941	CDK2	S1338	Y1339H	1339	Missense	proximal	1	no	0.522	9.262	EPSD	ICGC	8.148	Gain
CMGC_CDK_CDK2_CDK2_ST	O14497	ARID1A	P24941	CDK2	T1348	P1353L	1353	Missense	distal	5	no	15.419	15.459	EPSD	ICGC;COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	O14497	ARID1A	P24941	CDK2	T1348	S1352G	1352	Missense	distal	4	no	15.419	15.286	EPSD	ICGC;COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	O14497	ARID1A	P24941	CDK2	S1352	T1359I	1359	Missense	distal	7	no	14.485	14.846	EPSD	ICGC;COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	O14497	ARID1A	P24941	CDK2	S1352	P1353L	1353	Missense	proximal	1	no	14.485	4.664	EPSD	ICGC;COSMIC	8.148	Loss
CMGC_CDK_CDK2_CDK2_ST	O14497	ARID1A	P24941	CDK2	S1352	S1352G	1352	Missense	central	0	yes	14.485	0.000	EPSD	ICGC;COSMIC	8.148	Loss
CMGC_CDK_CDK2_CDK2_ST	Q15910	EZH2	P24941	CDK2	T345	P350S	350	Missense	distal	5	no	16.708	16.607	EPSD;PhosphoSitePlus	ICGC;COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	Q15910	EZH2	P24941	CDK2	T345	R342P	342	Missense	distal	-3	no	16.708	16.519	EPSD;PhosphoSitePlus	ICGC;COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	Q15910	EZH2	P24941	CDK2	T345	R349H	349	Missense	distal	4	no	16.708	16.590	EPSD;PhosphoSitePlus	ICGC;COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	Q15910	EZH2	P24941	CDK2	T367	S362N	362	Missense	distal	-5	no	11.019	11.082	EPSD	ICGC;COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	Q15910	EZH2	P24941	CDK2	T416	P417S	417	Missense	proximal	1	no	16.244	4.978	PhosphoSitePlus;EPSD	ICGC;COSMIC	8.148	Loss
CMGC_CDK_CDK2_CDK2_ST	Q7KZ85	SUPT6H	P24941	CDK2	S75	D77Y	77	Missense	proximal	2	no	8.965	9.026	EPSD	ICGC;GDSC;CCLE	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	Q7KZ85	SUPT6H	P24941	CDK2	S75	G72V	72	Missense	distal	-3	no	8.965	9.005	EPSD	ICGC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	Q7KZ85	SUPT6H	P24941	CDK2	T327	T329S	329	Missense	proximal	2	no	14.344	14.588	EPSD	ICGC;COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	Q7KZ85	SUPT6H	P24941	CDK2	T619	K622N	622	Missense	distal	3	no	12.869	9.599	EPSD	ICGC;COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	Q7KZ85	SUPT6H	P24941	CDK2	T835	F839V	839	Missense	distal	4	no	7.973	8.383	EPSD	ICGC;COSMIC	8.148	Gain
CMGC_CDK_CDK2_CDK2_ST	Q7KZ85	SUPT6H	P24941	CDK2	T1523	G1521A	1521	Missense	proximal	-2	no	11.752	12.511	PhosphoSitePlus	ICGC;COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	Q7KZ85	SUPT6H	P24941	CDK2	T1523	R1529S	1529	Missense	distal	6	no	11.752	11.770	PhosphoSitePlus	ICGC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	Q7KZ85	SUPT6H	P24941	CDK2	T1523	P1524L	1524	Missense	proximal	1	no	11.752	1.932	PhosphoSitePlus	ICGC;COSMIC	8.148	Loss
CMGC_CDK_CDK2_CDK2_ST	Q7KZ85	SUPT6H	P24941	CDK2	T1523	T1523P	1523	Missense	central	0	yes	11.752	0.000	PhosphoSitePlus	ICGC;GDSC	8.148	Loss
CMGC_CDK_CDK2_CDK2_ST	Q7KZ85	SUPT6H	P24941	CDK2	T1532	R1529S	1529	Missense	distal	-3	no	13.927	13.834	EPSD	ICGC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	Q7KZ85	SUPT6H	P24941	CDK2	T1532	A1534S	1534	Missense	proximal	2	no	13.927	13.969	EPSD	ICGC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	Q7KZ85	SUPT6H	P24941	CDK2	T1532	I1536V	1536	Missense	distal	4	no	13.927	14.183	EPSD	ICGC;COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	Q7KZ85	SUPT6H	P24941	CDK2	T1539	A1534S	1534	Missense	distal	-5	no	12.370	12.301	EPSD	ICGC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	Q7KZ85	SUPT6H	P24941	CDK2	T1539	I1536V	1536	Missense	distal	-3	no	12.370	12.493	EPSD	ICGC;COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	Q7KZ85	SUPT6H	P24941	CDK2	T1580	A1579V	1579	Missense	proximal	-1	no	12.153	12.380	EPSD	ICGC;COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	Q7KZ85	SUPT6H	P24941	CDK2	S1668	K1665N	1665	Missense	distal	-3	no	8.551	8.613	EPSD	ICGC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	Q7KZ85	SUPT6H	P24941	CDK2	S1668	D1673Y	1673	Missense	distal	5	no	8.551	8.451	EPSD	ICGC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	Q7KZ85	SUPT6H	P24941	CDK2	T1709	M1711V	1711	Missense	proximal	2	no	14.085	13.996	EPSD	ICGC;COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	Q7KZ85	SUPT6H	P24941	CDK2	T1709	A1714S	1714	Missense	distal	5	no	14.085	13.974	EPSD	ICGC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	Q7KZ85	SUPT6H	P24941	CDK2	T1709	D1716Y	1716	Missense	distal	7	no	14.085	13.668	EPSD	ICGC;COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	Q7KZ85	SUPT6H	P24941	CDK2	T1709	D1716N	1716	Missense	distal	7	no	14.085	13.305	EPSD	ICGC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	Q7KZ85	SUPT6H	P24941	CDK2	T1718	D1722N	1722	Missense	distal	4	no	13.489	13.534	EPSD	ICGC;COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	Q7KZ85	SUPT6H	P24941	CDK2	T1718	M1711V	1711	Missense	distal	-7	no	13.489	13.007	EPSD	ICGC;COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	Q7KZ85	SUPT6H	P24941	CDK2	T1718	A1714S	1714	Missense	distal	-4	no	13.489	13.902	EPSD	ICGC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	Q7KZ85	SUPT6H	P24941	CDK2	T1718	D1716Y	1716	Missense	proximal	-2	no	13.489	13.059	EPSD	ICGC;COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	Q7KZ85	SUPT6H	P24941	CDK2	T1718	D1722E	1722	Missense	distal	4	no	13.489	13.571	EPSD	ICGC;COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	Q7KZ85	SUPT6H	P24941	CDK2	T1718	D1716N	1716	Missense	proximal	-2	no	13.489	12.281	EPSD	ICGC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	Q12948	FOXC1	P24941	CDK2	S9	R4S	4	Missense	distal	-5	no	12.591	12.500	EPSD	ICGC;COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	Q12948	FOXC1	P24941	CDK2	T68	A63P	63	Missense	distal	-5	no	16.913	16.888	PhosphoSitePlus	ICGC;COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	Q12948	FOXC1	P24941	CDK2	T68	Q70H	70	Missense	proximal	2	no	16.913	16.932	PhosphoSitePlus	ICGC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	Q12948	FOXC1	P24941	CDK2	T68	K74R	74	Missense	distal	6	no	16.913	16.889	PhosphoSitePlus	ICGC;COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	Q12948	FOXC1	P24941	CDK2	S235	T232M	232	Missense	distal	-3	no	9.052	9.460	EPSD	ICGC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	Q12948	FOXC1	P24941	CDK2	S235	P234L	234	Missense	proximal	-1	no	9.052	8.873	EPSD	ICGC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	Q12948	FOXC1	P24941	CDK2	S241	P234L	234	Missense	distal	-7	no	12.910	12.916	EPSD	ICGC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	Q12948	FOXC1	P24941	CDK2	S259	S262N	262	Missense	distal	3	no	13.897	13.300	EPSD	ICGC;COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	Q12948	FOXC1	P24941	CDK2	S272	S272N	272	Missense	central	0	yes	14.206	0.000	EPSD	ICGC;COSMIC	8.148	Loss
CMGC_CDK_CDK2_CDK2_ST	Q12948	FOXC1	P24941	CDK2	S272	S276C	276	Missense	distal	4	no	14.206	13.446	EPSD	ICGC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	Q12948	FOXC1	P24941	CDK2	S521	S521C	521	Missense	central	0	yes	8.496	0.000	EPSD	ICGC;COSMIC	8.148	Loss
CMGC_CDK_CDK2_CDK2_ST	Q12948	FOXC1	P24941	CDK2	S521	L518F	518	Missense	distal	-3	no	8.496	8.754	EPSD	ICGC;COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	Q12948	FOXC1	P24941	CDK2	S521	G525W	525	Missense	distal	4	no	8.496	8.136	EPSD	ICGC;COSMIC	8.148	Loss
CMGC_CDK_CDK2_CDK2_ST	Q6UB35	MTHFD1L	P24941	CDK2	S62	S59N	59	Missense	distal	-3	no	12.891	12.816	EPSD	ICGC;COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	Q6UB35	MTHFD1L	P24941	CDK2	S271	P274L	274	Missense	distal	3	no	14.231	13.848	EPSD	ICGC;COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	Q6UB35	MTHFD1L	P24941	CDK2	T421	P424S	424	Missense	distal	3	no	11.399	11.433	EPSD	ICGC;COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	Q6UB35	MTHFD1L	P24941	CDK2	T421	A418S	418	Missense	distal	-3	no	11.399	11.553	EPSD	ICGC;COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	Q6UB35	MTHFD1L	P24941	CDK2	T421	A418V	418	Missense	distal	-3	no	11.399	11.600	EPSD	ICGC;COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	Q6UB35	MTHFD1L	P24941	CDK2	T423	P424S	424	Missense	proximal	1	no	11.488	0.222	EPSD	ICGC;COSMIC	8.148	Loss
CMGC_CDK_CDK2_CDK2_ST	Q6UB35	MTHFD1L	P24941	CDK2	T423	A418S	418	Missense	distal	-5	no	11.488	11.418	EPSD	ICGC;COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	Q6UB35	MTHFD1L	P24941	CDK2	T423	A418V	418	Missense	distal	-5	no	11.488	11.494	EPSD	ICGC;COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	Q6UB35	MTHFD1L	P24941	CDK2	S639	G640R	640	Missense	proximal	1	no	9.570	7.084	EPSD	ICGC;COSMIC	8.148	Loss
CMGC_CDK_CDK2_CDK2_ST	Q6UB35	MTHFD1L	P24941	CDK2	S639	G640W	640	Missense	proximal	1	no	9.570	1.660	EPSD	ICGC	8.148	Loss
CMGC_CDK_CDK2_CDK2_ST	Q6UB35	MTHFD1L	P24941	CDK2	S885	A890V	890	Missense	distal	5	no	14.109	14.066	EPSD	ICGC;COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	Q6UB35	MTHFD1L	P24941	CDK2	S885	S885C	885	Missense	central	0	yes	14.109	0.000	EPSD	ICGC;COSMIC	8.148	Loss
CMGC_CDK_CDK2_CDK2_ST	Q6UB35	MTHFD1L	P24941	CDK2	S885	A888T	888	Missense	distal	3	no	14.109	14.507	EPSD	ICGC;COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	Q15047	SETDB1	P24941	CDK2	T144	S142I	142	Missense	proximal	-2	no	11.022	11.519	EPSD	ICGC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	Q15047	SETDB1	P24941	CDK2	S189	Q187H	187	Missense	proximal	-2	no	10.057	9.614	EPSD	ICGC;COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	Q15047	SETDB1	P24941	CDK2	S189	D195N	195	Missense	distal	6	no	10.057	10.076	EPSD	ICGC;COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	Q15047	SETDB1	P24941	CDK2	S189	G196D	196	Missense	distal	7	no	10.057	10.073	EPSD	ICGC;COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	Q15047	SETDB1	P24941	CDK2	T443	G440S	440	Missense	distal	-3	no	9.880	9.872	EPSD	ICGC;COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	Q15047	SETDB1	P24941	CDK2	T443	G440C	440	Missense	distal	-3	no	9.880	9.879	EPSD	ICGC;COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	Q15047	SETDB1	P24941	CDK2	S468	F461L	461	Missense	distal	-7	no	13.337	12.971	EPSD	ICGC;COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	Q15047	SETDB1	P24941	CDK2	S468	L467I	467	Missense	proximal	-1	no	13.337	13.499	EPSD	ICGC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	Q15047	SETDB1	P24941	CDK2	S505	G500V	500	Missense	distal	-5	no	12.742	12.693	EPSD	ICGC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	Q15047	SETDB1	P24941	CDK2	S505	S498C	498	Missense	distal	-7	no	12.742	13.193	EPSD	ICGC;COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	Q15047	SETDB1	P24941	CDK2	S505	S504C	504	Missense	proximal	-1	no	12.742	13.086	EPSD	ICGC;COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	Q15047	SETDB1	P24941	CDK2	S508	N514H	514	Missense	distal	6	no	13.979	13.970	EPSD	ICGC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	Q15047	SETDB1	P24941	CDK2	S508	S504C	504	Missense	distal	-4	no	13.979	12.873	EPSD	ICGC;COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	Q15047	SETDB1	P24941	CDK2	S528	A534V	534	Missense	distal	6	no	12.702	12.704	EPSD	ICGC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	Q15047	SETDB1	P24941	CDK2	T700	I697T	697	Missense	distal	-3	no	14.090	14.030	EPSD	ICGC;COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	Q15047	SETDB1	P24941	CDK2	S906	D907H	907	Missense	proximal	1	no	8.602	10.088	EPSD	ICGC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	Q15047	SETDB1	P24941	CDK2	S906	D913A	913	Missense	distal	7	no	8.602	8.301	EPSD	ICGC;COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	Q15047	SETDB1	P24941	CDK2	S906	E899K	899	Missense	distal	-7	no	8.602	8.465	EPSD	ICGC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	Q15047	SETDB1	P24941	CDK2	T976	E974K	974	Missense	proximal	-2	no	11.996	12.597	EPSD	ICGC;CCLE	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	Q15047	SETDB1	P24941	CDK2	S1066	N1064S	1064	Missense	proximal	-2	no	16.411	17.102	PhosphoSitePlus	ICGC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	Q15047	SETDB1	P24941	CDK2	S1066	K1069N	1069	Missense	distal	3	no	16.411	13.140	PhosphoSitePlus	ICGC;COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	Q15047	SETDB1	P24941	CDK2	S1112	T1114P	1114	Missense	proximal	2	no	8.084	8.261	EPSD	ICGC;COSMIC	8.148	Gain
CMGC_CDK_CDK2_CDK2_ST	Q6PKG0	LARP1	P24941	CDK2	S75	P82H	82	Missense	distal	7	no	16.328	16.459	EPSD	ICGC;COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	Q6PKG0	LARP1	P24941	CDK2	S143	P144Q	144	Missense	proximal	1	no	14.543	6.631	EPSD	ICGC;COSMIC	8.148	Loss
CMGC_CDK_CDK2_CDK2_ST	Q6PKG0	LARP1	P24941	CDK2	S580	R578Q	578	Missense	proximal	-2	no	8.651	9.320	EPSD	ICGC;COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	Q6PKG0	LARP1	P24941	CDK2	S774	S774I	774	Missense	central	0	yes	15.408	0.000	EPSD;PhosphoSitePlus	ICGC	8.148	Loss
CMGC_CDK_CDK2_CDK2_ST	Q8NBZ0	INO80E	P24941	CDK2	T90	A92S	92	Missense	proximal	2	no	13.621	13.663	EPSD	ICGC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	Q8NBZ0	INO80E	P24941	CDK2	T90	K86N	86	Missense	distal	-4	no	13.621	13.840	EPSD	ICGC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	Q8NBZ0	INO80E	P24941	CDK2	S98	A104T	104	Missense	distal	6	no	12.680	12.692	EPSD	ICGC;COSMIC;GDSC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	Q8NBZ0	INO80E	P24941	CDK2	S98	P100L	100	Missense	proximal	2	no	12.680	12.573	EPSD	ICGC;COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	Q8NBZ0	INO80E	P24941	CDK2	S106	A104T	104	Missense	proximal	-2	no	10.328	10.278	EPSD	ICGC;COSMIC;GDSC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	Q8NBZ0	INO80E	P24941	CDK2	S127	G124R	124	Missense	distal	-3	no	12.327	12.412	EPSD	ICGC;COSMIC;GDSC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	Q8NBZ0	INO80E	P24941	CDK2	S127	P126S	126	Missense	proximal	-1	no	12.327	11.856	EPSD	ICGC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	Q8NBZ0	INO80E	P24941	CDK2	S154	R160Q	160	Missense	distal	6	no	14.442	14.464	PhosphoSitePlus	ICGC;COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	Q9UPN3	MACF1	P24941	CDK2	T212	V207L	207	Missense	distal	-5	no	10.890	10.871	EPSD	ICGC;COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	Q9UPN3	MACF1	P24941	CDK2	T212	T208I	208	Missense	distal	-4	no	10.890	10.573	EPSD	ICGC;COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	Q9UPN3	MACF1	P24941	CDK2	S280	D275N	275	Missense	distal	-5	no	15.487	15.448	EPSD	ICGC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	Q9UPN3	MACF1	P24941	CDK2	S647	K645M	645	Missense	proximal	-2	no	8.357	6.787	EPSD	ICGC;COSMIC	8.148	Loss
CMGC_CDK_CDK2_CDK2_ST	Q9UPN3	MACF1	P24941	CDK2	S862	R861H	861	Missense	proximal	-1	no	15.065	14.614	EPSD	ICGC;COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	Q9UPN3	MACF1	P24941	CDK2	S862	P863Q	863	Missense	proximal	1	no	15.065	7.154	EPSD	ICGC	8.148	Loss
CMGC_CDK_CDK2_CDK2_ST	Q9UPN3	MACF1	P24941	CDK2	S898	V905L	905	Missense	distal	7	no	8.562	8.334	EPSD	ICGC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	Q9UPN3	MACF1	P24941	CDK2	S907	V905L	905	Missense	proximal	-2	no	13.460	13.885	EPSD	ICGC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	Q9UPN3	MACF1	P24941	CDK2	S1122	Q1121H	1121	Missense	proximal	-1	no	12.918	13.345	EPSD	ICGC;COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	Q9UPN3	MACF1	P24941	CDK2	S1363	G1369V	1369	Missense	distal	6	no	9.734	9.744	EPSD	ICGC;COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	Q9UPN3	MACF1	P24941	CDK2	S1363	K1366E	1366	Missense	distal	3	no	9.734	7.649	EPSD	ICGC;COSMIC	8.148	Loss
CMGC_CDK_CDK2_CDK2_ST	Q9UPN3	MACF1	P24941	CDK2	S1367	R1372C	1372	Missense	distal	5	no	16.855	16.983	EPSD	ICGC;COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	Q9UPN3	MACF1	P24941	CDK2	S1367	G1369V	1369	Missense	proximal	2	no	16.855	16.860	EPSD	ICGC;COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	Q9UPN3	MACF1	P24941	CDK2	S1367	R1372L	1372	Missense	distal	5	no	16.855	16.789	EPSD	ICGC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	Q9UPN3	MACF1	P24941	CDK2	S1367	R1371L	1371	Missense	distal	4	no	16.855	17.087	EPSD	ICGC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	Q9UPN3	MACF1	P24941	CDK2	S1367	K1366E	1366	Missense	proximal	-1	no	16.855	17.740	EPSD	ICGC;COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	Q9UPN3	MACF1	P24941	CDK2	S1367	R1371C	1371	Missense	distal	4	no	16.855	16.228	EPSD	ICGC;COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	Q9UPN3	MACF1	P24941	CDK2	S1367	R1372H	1372	Missense	distal	5	no	16.855	16.827	EPSD	ICGC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	Q9UPN3	MACF1	P24941	CDK2	S2006	E2012Q	2012	Missense	distal	6	no	13.359	13.367	EPSD	ICGC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	Q9UPN3	MACF1	P24941	CDK2	S2006	S1999F	1999	Missense	distal	-7	no	13.359	13.910	EPSD	ICGC;COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	Q9UPN3	MACF1	P24941	CDK2	T2020	E2022Q	2022	Missense	proximal	2	no	14.723	14.686	EPSD	ICGC;COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	Q9UPN3	MACF1	P24941	CDK2	T2020	K2019T	2019	Missense	proximal	-1	no	14.723	14.560	EPSD	ICGC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	Q9UPN3	MACF1	P24941	CDK2	S2051	E2055G	2055	Missense	distal	4	no	8.576	8.439	EPSD	ICGC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	Q9UPN3	MACF1	P24941	CDK2	T2063	C2062F	2062	Missense	proximal	-1	no	8.202	9.115	EPSD	ICGC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	Q9UPN3	MACF1	P24941	CDK2	T2063	R2059L	2059	Missense	distal	-4	no	8.202	8.387	EPSD	ICGC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	Q9UPN3	MACF1	P24941	CDK2	T2063	R2059W	2059	Missense	distal	-4	no	8.202	7.444	EPSD	ICGC;COSMIC	8.148	Loss
CMGC_CDK_CDK2_CDK2_ST	Q9UPN3	MACF1	P24941	CDK2	T2160	H2165Q	2165	Missense	distal	5	no	18.674	18.556	EPSD	ICGC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	Q9UPN3	MACF1	P24941	CDK2	T2160	P2161S	2161	Missense	proximal	1	no	18.674	7.408	EPSD	ICGC;COSMIC	8.148	Loss
CMGC_CDK_CDK2_CDK2_ST	Q9UPN3	MACF1	P24941	CDK2	T2160	D2154Y	2154	Missense	distal	-6	no	18.674	18.675	EPSD	ICGC;COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	Q9UPN3	MACF1	P24941	CDK2	S2517	G2511C	2511	Missense	distal	-6	no	9.704	9.707	EPSD	ICGC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	Q9UPN3	MACF1	P24941	CDK2	T2586	E2581Q	2581	Missense	distal	-5	no	8.477	8.440	EPSD	ICGC;COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	Q9UPN3	MACF1	P24941	CDK2	T2586	Q2583R	2583	Missense	distal	-3	no	8.477	8.607	EPSD	ICGC;COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	Q9UPN3	MACF1	P24941	CDK2	T2586	V2582F	2582	Missense	distal	-4	no	8.477	7.917	EPSD	ICGC	8.148	Loss
CMGC_CDK_CDK2_CDK2_ST	Q9UPN3	MACF1	P24941	CDK2	S2594	A2601T	2601	Missense	distal	7	no	10.329	9.640	EPSD	ICGC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	Q9UPN3	MACF1	P24941	CDK2	S2594	L2598F	2598	Missense	distal	4	no	10.329	10.034	EPSD	ICGC;COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	Q9UPN3	MACF1	P24941	CDK2	S2647	L2652R	2652	Missense	distal	5	no	9.433	9.499	EPSD	ICGC;COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	Q9UPN3	MACF1	P24941	CDK2	S2647	L2652I	2652	Missense	distal	5	no	9.433	9.486	EPSD	ICGC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	Q9UPN3	MACF1	P24941	CDK2	S2926	H2927D	2927	Missense	proximal	1	no	11.357	9.872	EPSD	ICGC;COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	Q9UPN3	MACF1	P24941	CDK2	S2926	S2926Y	2926	Missense	central	0	yes	11.357	0.000	EPSD	ICGC;COSMIC	8.148	Loss
CMGC_CDK_CDK2_CDK2_ST	Q9UPN3	MACF1	P24941	CDK2	S2926	I2924S	2924	Missense	proximal	-2	no	11.357	10.860	EPSD	ICGC;COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	Q9UPN3	MACF1	P24941	CDK2	S3016	P3022H	3022	Missense	distal	6	no	10.568	10.563	EPSD	ICGC;COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	Q9UPN3	MACF1	P24941	CDK2	S3016	S3020G	3020	Missense	distal	4	no	10.568	10.434	EPSD	ICGC;COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	Q9UPN3	MACF1	P24941	CDK2	S3020	M3025I	3025	Missense	distal	5	no	8.688	8.473	EPSD	ICGC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	Q9UPN3	MACF1	P24941	CDK2	S3020	P3022H	3022	Missense	proximal	2	no	8.688	8.765	EPSD	ICGC;COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	Q9UPN3	MACF1	P24941	CDK2	S3020	S3020G	3020	Missense	central	0	yes	8.688	0.000	EPSD	ICGC;COSMIC	8.148	Loss
CMGC_CDK_CDK2_CDK2_ST	Q9UPN3	MACF1	P24941	CDK2	T3111	F3107L	3107	Missense	distal	-4	no	11.096	11.645	EPSD	ICGC;COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	Q9UPN3	MACF1	P24941	CDK2	T3111	E3115Q	3115	Missense	distal	4	no	11.096	11.140	EPSD	ICGC;COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	Q9UPN3	MACF1	P24941	CDK2	T3111	C3109F	3109	Missense	proximal	-2	no	11.096	11.044	EPSD	ICGC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	Q9UPN3	MACF1	P24941	CDK2	T3111	S3104N	3104	Missense	distal	-7	no	11.096	11.194	EPSD	ICGC;COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	Q9UPN3	MACF1	P24941	CDK2	S3298	Q3293H	3293	Missense	distal	-5	no	15.057	15.104	EPSD	ICGC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	Q9UPN3	MACF1	P24941	CDK2	T3323	E3326K	3326	Missense	distal	3	no	14.177	16.263	EPSD	ICGC;COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	Q9UPN3	MACF1	P24941	CDK2	T3323	E3321Q	3321	Missense	proximal	-2	no	14.177	14.725	EPSD	ICGC;COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	Q9UPN3	MACF1	P24941	CDK2	S3331	E3326K	3326	Missense	distal	-5	no	12.373	12.338	EPSD	ICGC;COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	Q9UPN3	MACF1	P24941	CDK2	S3331	P3338L	3338	Missense	distal	7	no	12.373	12.403	EPSD	ICGC;COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	Q9UPN3	MACF1	P24941	CDK2	T3337	T3341I	3341	Missense	distal	4	no	11.559	11.247	EPSD	ICGC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	Q9UPN3	MACF1	P24941	CDK2	T3337	E3344Q	3344	Missense	distal	7	no	11.559	11.360	EPSD	ICGC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	Q9UPN3	MACF1	P24941	CDK2	T3337	P3338L	3338	Missense	proximal	1	no	11.559	1.738	EPSD	ICGC;COSMIC	8.148	Loss
CMGC_CDK_CDK2_CDK2_ST	Q9UPN3	MACF1	P24941	CDK2	T3337	F3339L	3339	Missense	proximal	2	no	11.559	11.201	EPSD	ICGC;COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	Q9UPN3	MACF1	P24941	CDK2	S3657	L3659F	3659	Missense	proximal	2	no	8.245	8.603	EPSD	ICGC;COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	Q9UPN3	MACF1	P24941	CDK2	S3657	Q3653K	3653	Missense	distal	-4	no	8.245	8.382	EPSD	ICGC;COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	Q9UPN3	MACF1	P24941	CDK2	S3657	A3651D	3651	Missense	distal	-6	no	8.245	8.244	EPSD	ICGC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	Q9UPN3	MACF1	P24941	CDK2	S3657	S3650C	3650	Missense	distal	-7	no	8.245	8.696	EPSD	ICGC;COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	Q9UPN3	MACF1	P24941	CDK2	S3657	L3662V	3662	Missense	distal	5	no	8.245	8.172	EPSD	ICGC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	Q9UPN3	MACF1	P24941	CDK2	S3692	R3694L	3694	Missense	proximal	2	no	13.892	13.626	EPSD	ICGC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	Q9UPN3	MACF1	P24941	CDK2	S3914	K3910N	3910	Missense	distal	-4	no	13.081	13.301	EPSD	ICGC;COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	Q9UPN3	MACF1	P24941	CDK2	S3914	L3921M	3921	Missense	distal	7	no	13.081	13.596	EPSD	ICGC;COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	Q9UPN3	MACF1	P24941	CDK2	S3914	S3914N	3914	Missense	central	0	yes	13.081	0.000	EPSD	ICGC;COSMIC	8.148	Loss
CMGC_CDK_CDK2_CDK2_ST	Q9UPN3	MACF1	P24941	CDK2	T3917	K3910N	3910	Missense	distal	-7	no	8.529	8.495	EPSD	ICGC;COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	Q9UPN3	MACF1	P24941	CDK2	T3917	L3921M	3921	Missense	distal	4	no	8.529	7.996	EPSD	ICGC;COSMIC	8.148	Loss
CMGC_CDK_CDK2_CDK2_ST	Q9UPN3	MACF1	P24941	CDK2	T3917	S3914N	3914	Missense	distal	-3	no	8.529	8.455	EPSD	ICGC;COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	Q9UPN3	MACF1	P24941	CDK2	T3917	R3924W	3924	Missense	distal	7	no	8.529	8.929	EPSD	ICGC;COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	Q9UPN3	MACF1	P24941	CDK2	S4496	P4497L	4497	Missense	proximal	1	no	13.903	4.082	EPSD	ICGC	8.148	Loss
CMGC_CDK_CDK2_CDK2_ST	Q9UPN3	MACF1	P24941	CDK2	S4496	A4493D	4493	Missense	distal	-3	no	13.903	14.026	EPSD	ICGC;COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	Q9UPN3	MACF1	P24941	CDK2	S4496	D4492N	4492	Missense	distal	-4	no	13.903	13.514	EPSD	ICGC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	Q9UPN3	MACF1	P24941	CDK2	S4496	V4503A	4503	Missense	distal	7	no	13.903	14.029	EPSD	ICGC;COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	Q9UPN3	MACF1	P24941	CDK2	S4521	K4528N	4528	Missense	distal	7	no	13.515	13.708	EPSD	ICGC;COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	Q9UPN3	MACF1	P24941	CDK2	S5592	P5593L	5593	Missense	proximal	1	no	13.211	3.390	EPSD	ICGC	8.148	Loss
CMGC_CDK_CDK2_CDK2_ST	Q9UPN3	MACF1	P24941	CDK2	S6032	G6034D	6034	Missense	proximal	2	no	12.843	12.723	EPSD	ICGC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	Q9UPN3	MACF1	P24941	CDK2	S6032	P6037L	6037	Missense	distal	5	no	12.843	12.883	EPSD	ICGC;COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	Q9UPN3	MACF1	P24941	CDK2	S6032	D6025Y	6025	Missense	distal	-7	no	12.843	12.728	EPSD	ICGC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	Q9UPN3	MACF1	P24941	CDK2	S6032	S6038F	6038	Missense	distal	6	no	12.843	12.824	EPSD	ICGC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	Q9UPN3	MACF1	P24941	CDK2	S6032	D6025N	6025	Missense	distal	-7	no	12.843	12.521	EPSD	ICGC;COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	Q9UPN3	MACF1	P24941	CDK2	S6408	K6411N	6411	Missense	distal	3	no	11.155	7.885	EPSD	ICGC;COSMIC	8.148	Loss
CMGC_CDK_CDK2_CDK2_ST	Q9UPN3	MACF1	P24941	CDK2	S6408	D6405G	6405	Missense	distal	-3	no	11.155	11.193	EPSD	ICGC;COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	Q9UPN3	MACF1	P24941	CDK2	S6408	S6402I	6402	Missense	distal	-6	no	11.155	11.158	EPSD	ICGC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	Q9UPN3	MACF1	P24941	CDK2	S6408	S6402T	6402	Missense	distal	-6	no	11.155	11.156	EPSD	ICGC;COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	Q9UPN3	MACF1	P24941	CDK2	S6408	S6406C	6406	Missense	proximal	-2	no	11.155	10.744	EPSD	ICGC;COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	Q9UPN3	MACF1	P24941	CDK2	T6505	Q6508K	6508	Missense	distal	3	no	7.148	9.880	EPSD	ICGC;COSMIC	8.148	Gain
CMGC_CDK_CDK2_CDK2_ST	Q9UPN3	MACF1	P24941	CDK2	T7213	S7209C	7209	Missense	distal	-4	no	15.589	14.483	PhosphoSitePlus	ICGC;COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	Q9UPN3	MACF1	P24941	CDK2	T7213	E7206D	7206	Missense	distal	-7	no	15.589	15.740	PhosphoSitePlus	ICGC;COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	Q9UPN3	MACF1	P24941	CDK2	T7213	G7219C	7219	Missense	distal	6	no	15.589	15.586	PhosphoSitePlus	ICGC;COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	Q9UPN3	MACF1	P24941	CDK2	T7213	G7207D	7207	Missense	distal	-6	no	15.589	15.585	PhosphoSitePlus	ICGC;COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	Q9UPN3	MACF1	P24941	CDK2	S7230	R7233C	7233	Missense	distal	3	no	15.485	9.121	EPSD	ICGC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	Q9UPN3	MACF1	P24941	CDK2	S7230	S7235I	7235	Missense	distal	5	no	15.485	15.679	EPSD	ICGC;COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	Q9UPN3	MACF1	P24941	CDK2	S7251	M7248L	7248	Missense	distal	-3	no	14.261	13.822	EPSD	ICGC;COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	Q9UPN3	MACF1	P24941	CDK2	S7251	S7251F	7251	Missense	central	0	yes	14.261	0.000	EPSD	ICGC;COSMIC;CCLE	8.148	Loss
CMGC_CDK_CDK2_CDK2_ST	Q9UPN3	MACF1	P24941	CDK2	S7251	P7255T	7255	Missense	distal	4	no	14.261	14.544	EPSD	ICGC;COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	Q9UPN3	MACF1	P24941	CDK2	S7251	S7244T	7244	Missense	distal	-7	no	14.261	14.438	EPSD	ICGC;COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	Q9UPN3	MACF1	P24941	CDK2	T7254	M7248L	7248	Missense	distal	-6	no	12.488	12.481	EPSD	ICGC;COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	Q9UPN3	MACF1	P24941	CDK2	T7254	S7251F	7251	Missense	distal	-3	no	12.488	12.580	EPSD	ICGC;COSMIC;CCLE	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	Q9UPN3	MACF1	P24941	CDK2	T7254	P7255T	7255	Missense	proximal	1	no	12.488	2.531	EPSD	ICGC;COSMIC	8.148	Loss
CMGC_CDK_CDK2_CDK2_ST	Q9UPN3	MACF1	P24941	CDK2	T7273	R7280L	7280	Missense	distal	7	no	11.902	11.443	EPSD	ICGC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	Q9UPN3	MACF1	P24941	CDK2	T7273	T7273K	7273	Missense	central	0	yes	11.902	0.000	EPSD	ICGC;COSMIC	8.148	Loss
CMGC_CDK_CDK2_CDK2_ST	Q03252	LMNB2	P24941	CDK2	T23	A19T	19	Missense	distal	-4	no	10.654	10.879	EPSD	ICGC;COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	Q03252	LMNB2	P24941	CDK2	S90	T86A	86	Missense	distal	-4	no	10.082	9.857	EPSD	ICGC;COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	Q03252	LMNB2	P24941	CDK2	S541	G535V	535	Missense	distal	-6	no	15.989	15.988	EPSD	ICGC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	P33993	MCM7	P24941	CDK2	S121	P122T	122	Missense	proximal	1	no	14.179	4.222	PhosphoSitePlus;EPSD	ICGC	8.148	Loss
CMGC_CDK_CDK2_CDK2_ST	P33993	MCM7	P24941	CDK2	S121	Q125K	125	Missense	distal	4	no	14.179	14.520	PhosphoSitePlus;EPSD	ICGC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	P33993	MCM7	P24941	CDK2	S365	Q364K	364	Missense	proximal	-1	no	15.149	15.356	EPSD;PhosphoSitePlus	ICGC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	P33993	MCM7	P24941	CDK2	S365	G360V	360	Missense	distal	-5	no	15.149	15.100	EPSD;PhosphoSitePlus	ICGC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	P33993	MCM7	P24941	CDK2	S365	R367P	367	Missense	proximal	2	no	15.149	14.990	EPSD;PhosphoSitePlus	ICGC;COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	P33993	MCM7	P24941	CDK2	S365	R372W	372	Missense	distal	7	no	15.149	15.548	EPSD;PhosphoSitePlus	ICGC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	P33993	MCM7	P24941	CDK2	S365	G360E	360	Missense	distal	-5	no	15.149	15.106	EPSD;PhosphoSitePlus	ICGC;COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	P33993	MCM7	P24941	CDK2	S410	S409Y	409	Missense	proximal	-1	no	7.708	8.618	EPSD	ICGC;COSMIC	8.148	Gain
CMGC_CDK_CDK2_CDK2_ST	Q9UIF9	BAZ2A	P24941	CDK2	S135	R131Q	131	Missense	distal	-4	no	13.535	13.560	EPSD	ICGC;COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	Q9UIF9	BAZ2A	P24941	CDK2	S135	P136T	136	Missense	proximal	1	no	13.535	3.578	EPSD	ICGC;COSMIC	8.148	Loss
CMGC_CDK_CDK2_CDK2_ST	Q9UIF9	BAZ2A	P24941	CDK2	S367	T360K	360	Missense	distal	-7	no	9.866	9.822	EPSD	ICGC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	Q9UIF9	BAZ2A	P24941	CDK2	S367	T362S	362	Missense	distal	-5	no	9.866	9.823	EPSD	ICGC;COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	Q9UIF9	BAZ2A	P24941	CDK2	S492	V498L	498	Missense	distal	6	no	11.721	11.724	EPSD	ICGC;COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	Q9UIF9	BAZ2A	P24941	CDK2	S496	V498L	498	Missense	proximal	2	no	13.083	12.853	EPSD	ICGC;COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	Q9UIF9	BAZ2A	P24941	CDK2	S496	S500F	500	Missense	distal	4	no	13.083	12.887	EPSD	ICGC;COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	Q9UIF9	BAZ2A	P24941	CDK2	S500	V498L	498	Missense	proximal	-2	no	11.090	11.515	EPSD	ICGC;COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	Q9UIF9	BAZ2A	P24941	CDK2	S500	P506L	506	Missense	distal	6	no	11.090	11.091	EPSD	ICGC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	Q9UIF9	BAZ2A	P24941	CDK2	S500	P506S	506	Missense	distal	6	no	11.090	11.091	EPSD	ICGC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	Q9UIF9	BAZ2A	P24941	CDK2	S500	S500F	500	Missense	central	0	yes	11.090	0.000	EPSD	ICGC;COSMIC	8.148	Loss
CMGC_CDK_CDK2_CDK2_ST	Q9UIF9	BAZ2A	P24941	CDK2	S509	P506L	506	Missense	distal	-3	no	14.470	14.399	PhosphoSitePlus	ICGC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	Q9UIF9	BAZ2A	P24941	CDK2	S509	P506S	506	Missense	distal	-3	no	14.470	14.566	PhosphoSitePlus	ICGC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	Q9UIF9	BAZ2A	P24941	CDK2	T548	V552A	552	Missense	distal	4	no	13.987	13.800	EPSD	ICGC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	Q9UIF9	BAZ2A	P24941	CDK2	T548	V541A	541	Missense	distal	-7	no	13.987	14.132	EPSD	ICGC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	Q9UIF9	BAZ2A	P24941	CDK2	S613	R615P	615	Missense	proximal	2	no	15.705	15.547	EPSD	ICGC;COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	Q9UIF9	BAZ2A	P24941	CDK2	S613	R606C	606	Missense	distal	-7	no	15.705	15.633	EPSD	ICGC;COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	Q9UIF9	BAZ2A	P24941	CDK2	S613	P617T	617	Missense	distal	4	no	15.705	15.988	EPSD	ICGC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	Q9UIF9	BAZ2A	P24941	CDK2	T803	T800N	800	Missense	distal	-3	no	8.115	8.176	EPSD	ICGC	8.148	Gain
CMGC_CDK_CDK2_CDK2_ST	Q9UIF9	BAZ2A	P24941	CDK2	T803	A802D	802	Missense	proximal	-1	no	8.115	9.141	EPSD	ICGC;COSMIC	8.148	Gain
CMGC_CDK_CDK2_CDK2_ST	Q9UIF9	BAZ2A	P24941	CDK2	T803	R810W	810	Missense	distal	7	no	8.115	8.515	EPSD	ICGC	8.148	Gain
CMGC_CDK_CDK2_CDK2_ST	Q9UIF9	BAZ2A	P24941	CDK2	S1350	D1345E	1345	Missense	distal	-5	no	13.583	13.563	EPSD	ICGC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	Q9UIF9	BAZ2A	P24941	CDK2	S1370	F1374I	1374	Missense	distal	4	no	12.068	12.222	EPSD	ICGC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	Q9UIF9	BAZ2A	P24941	CDK2	T1377	F1374I	1374	Missense	distal	-3	no	13.296	13.129	EPSD	ICGC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	Q9UIF9	BAZ2A	P24941	CDK2	S1531	Q1534K	1534	Missense	distal	3	no	8.553	11.286	EPSD	ICGC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	Q9UIF9	BAZ2A	P24941	CDK2	S1531	R1527L	1527	Missense	distal	-4	no	8.553	8.738	EPSD	ICGC;COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	Q9UIF9	BAZ2A	P24941	CDK2	S1531	R1527W	1527	Missense	distal	-4	no	8.553	7.796	EPSD	ICGC;COSMIC	8.148	Loss
CMGC_CDK_CDK2_CDK2_ST	Q9UIF9	BAZ2A	P24941	CDK2	S1770	R1768L	1768	Missense	proximal	-2	no	10.776	11.788	EPSD	ICGC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	Q9UIF9	BAZ2A	P24941	CDK2	S1783	R1789Q	1789	Missense	distal	6	no	17.831	17.853	EPSD	ICGC;COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	Q9UIF9	BAZ2A	P24941	CDK2	S1783	R1787W	1787	Missense	distal	4	no	17.831	17.471	EPSD	ICGC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	P22234	PAICS	P24941	CDK2	S27	D26G	26	Missense	proximal	-1	no	18.378	18.671	PhosphoSitePlus	ICGC;COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	Q6Y7W6	GIGYF2	P24941	CDK2	S26	G21C	21	Missense	distal	-5	no	13.041	13.042	EPSD	ICGC;COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	Q6Y7W6	GIGYF2	P24941	CDK2	S26	S30Y	30	Missense	distal	4	no	13.041	13.227	EPSD	ICGC;COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	Q6Y7W6	GIGYF2	P24941	CDK2	S30	S30Y	30	Missense	central	0	yes	13.058	0.000	PhosphoSitePlus;EPSD	ICGC;COSMIC	8.148	Loss
CMGC_CDK_CDK2_CDK2_ST	Q6Y7W6	GIGYF2	P24941	CDK2	T85	A80T	80	Missense	distal	-5	no	8.581	8.555	EPSD	ICGC;COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	Q6Y7W6	GIGYF2	P24941	CDK2	S158	W161C	161	Missense	distal	3	no	8.312	4.588	EPSD	ICGC;COSMIC	8.148	Loss
CMGC_CDK_CDK2_CDK2_ST	Q9NXR1	NDE1	P24941	CDK2	T215	H219N	219	Missense	distal	4	no	13.557	13.774	EPSD	ICGC;COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	Q9NXR1	NDE1	P24941	CDK2	T286	S291Y	291	Missense	distal	5	no	8.340	8.515	EPSD	ICGC;COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	Q9NXR1	NDE1	P24941	CDK2	S328	G324W	324	Missense	distal	-4	no	9.306	8.623	EPSD	ICGC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	Q9NXR1	NDE1	P24941	CDK2	S328	P334L	334	Missense	distal	6	no	9.306	9.307	EPSD	ICGC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	Q9NXR1	NDE1	P24941	CDK2	S328	S333L	333	Missense	distal	5	no	9.306	9.447	EPSD	ICGC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	Q9NXR1	NDE1	P24941	CDK2	S328	S331L	331	Missense	distal	3	no	9.306	8.889	EPSD	ICGC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	Q9NXR1	NDE1	P24941	CDK2	S333	P334L	334	Missense	proximal	1	no	13.283	3.462	EPSD	ICGC	8.148	Loss
CMGC_CDK_CDK2_CDK2_ST	Q9NXR1	NDE1	P24941	CDK2	S333	Q339H	339	Missense	distal	6	no	13.283	13.273	EPSD	ICGC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	Q9NXR1	NDE1	P24941	CDK2	S333	S337L	337	Missense	distal	4	no	13.283	13.382	EPSD	ICGC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	Q9NXR1	NDE1	P24941	CDK2	S333	S333L	333	Missense	central	0	yes	13.283	0.000	EPSD	ICGC	8.148	Loss
CMGC_CDK_CDK2_CDK2_ST	Q9NXR1	NDE1	P24941	CDK2	S333	S331L	331	Missense	proximal	-2	no	13.283	13.710	EPSD	ICGC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	Q8WUM0	NUP133	P24941	CDK2	S7	A5T	5	Missense	proximal	-2	no	13.860	13.811	EPSD	ICGC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	Q8WUM0	NUP133	P24941	CDK2	T10	A5T	5	Missense	distal	-5	no	11.733	11.707	EPSD	ICGC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	Q8WUM0	NUP133	P24941	CDK2	T28	G24W	24	Missense	distal	-4	no	11.885	11.203	EPSD	ICGC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	P46013	MKI67	P24941	CDK2	S235	W238R	238	Missense	distal	3	no	13.170	15.810	EPSD	ICGC;COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	P46013	MKI67	P24941	CDK2	S308	P309T	309	Missense	proximal	1	no	13.943	3.986	EPSD	ICGC	8.148	Loss
CMGC_CDK_CDK2_CDK2_ST	P46013	MKI67	P24941	CDK2	S308	A302T	302	Missense	distal	-6	no	13.943	13.944	EPSD	ICGC;COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	P46013	MKI67	P24941	CDK2	T328	V323M	323	Missense	distal	-5	no	17.767	17.843	EPSD	ICGC;GDSC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	P46013	MKI67	P24941	CDK2	T328	R321K	321	Missense	distal	-7	no	17.767	17.376	EPSD	ICGC;COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	P46013	MKI67	P24941	CDK2	T347	P342Q	342	Missense	distal	-5	no	9.044	9.045	EPSD	ICGC;COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	P46013	MKI67	P24941	CDK2	T347	Q353R	353	Missense	distal	6	no	9.044	9.022	EPSD	ICGC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	P46013	MKI67	P24941	CDK2	S357	Q353R	353	Missense	distal	-4	no	15.647	15.622	PhosphoSitePlus	ICGC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	P46013	MKI67	P24941	CDK2	T391	R393G	393	Missense	proximal	2	no	16.142	16.101	EPSD	ICGC;COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	P46013	MKI67	P24941	CDK2	T391	R393K	393	Missense	proximal	2	no	16.142	15.842	EPSD	ICGC;COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	P46013	MKI67	P24941	CDK2	T391	D387V	387	Missense	distal	-4	no	16.142	15.567	EPSD	ICGC;COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	P46013	MKI67	P24941	CDK2	T401	P402Q	402	Missense	proximal	1	no	17.455	9.543	EPSD	ICGC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	P46013	MKI67	P24941	CDK2	T401	R400Q	400	Missense	proximal	-1	no	17.455	16.577	EPSD	ICGC;COSMIC;GDSC;CCLE	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	P46013	MKI67	P24941	CDK2	T401	A403V	403	Missense	proximal	2	no	17.455	17.553	EPSD	ICGC;COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	P46013	MKI67	P24941	CDK2	T694	T694K	694	Missense	central	0	yes	15.027	0.000	EPSD	ICGC	8.148	Loss
CMGC_CDK_CDK2_CDK2_ST	P46013	MKI67	P24941	CDK2	T1017	P1012T	1012	Missense	distal	-5	no	14.787	14.786	EPSD	ICGC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	P46013	MKI67	P24941	CDK2	T1017	P1018S	1018	Missense	proximal	1	no	14.787	3.521	EPSD	ICGC;COSMIC	8.148	Loss
CMGC_CDK_CDK2_CDK2_ST	P46013	MKI67	P24941	CDK2	T1019	P1012T	1012	Missense	distal	-7	no	9.528	9.525	EPSD	ICGC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	P46013	MKI67	P24941	CDK2	T1019	P1018S	1018	Missense	proximal	-1	no	9.528	9.056	EPSD	ICGC;COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	P46013	MKI67	P24941	CDK2	S1071	K1069E	1069	Missense	proximal	-2	no	12.202	11.601	EPSD	ICGC;COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	P46013	MKI67	P24941	CDK2	T1120	T1124M	1124	Missense	distal	4	no	9.578	8.874	EPSD	ICGC;COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	P46013	MKI67	P24941	CDK2	T1120	T1125P	1125	Missense	distal	5	no	9.578	9.603	EPSD	ICGC;COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	P46013	MKI67	P24941	CDK2	T1124	T1125P	1125	Missense	proximal	1	no	2.061	12.018	EPSD	ICGC;COSMIC	8.148	Gain
CMGC_CDK_CDK2_CDK2_ST	P46013	MKI67	P24941	CDK2	S1131	T1124M	1124	Missense	distal	-7	no	15.154	15.657	EPSD	ICGC;COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	P46013	MKI67	P24941	CDK2	T1485	T1489P	1489	Missense	distal	4	no	8.583	8.301	EPSD	ICGC;COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	P46013	MKI67	P24941	CDK2	T1747	P1748S	1748	Missense	proximal	1	no	15.182	3.916	EPSD	ICGC;COSMIC	8.148	Loss
CMGC_CDK_CDK2_CDK2_ST	P46013	MKI67	P24941	CDK2	T1869	T1871N	1871	Missense	proximal	2	no	14.825	14.932	EPSD	ICGC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	P46013	MKI67	P24941	CDK2	T1923	L1930F	1930	Missense	distal	7	no	13.948	14.620	EPSD	ICGC;COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	P46013	MKI67	P24941	CDK2	T1943	A1950S	1950	Missense	distal	7	no	13.434	12.897	EPSD	ICGC;COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	P46013	MKI67	P24941	CDK2	T1972	T1977N	1977	Missense	distal	5	no	9.746	9.874	EPSD	ICGC;COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	P46013	MKI67	P24941	CDK2	T1972	T1972M	1972	Missense	central	0	yes	9.746	0.000	EPSD	ICGC;COSMIC	8.148	Loss
CMGC_CDK_CDK2_CDK2_ST	P46013	MKI67	P24941	CDK2	T1972	D1974H	1974	Missense	proximal	2	no	9.746	9.827	EPSD	ICGC;COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	P46013	MKI67	P24941	CDK2	S1983	T1977N	1977	Missense	distal	-6	no	13.963	13.962	EPSD	ICGC;COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	P46013	MKI67	P24941	CDK2	T1991	S1995R	1995	Missense	distal	4	no	14.501	14.367	EPSD	ICGC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	P46013	MKI67	P24941	CDK2	T2065	E2069D	2069	Missense	distal	4	no	13.372	13.290	EPSD	ICGC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	P46013	MKI67	P24941	CDK2	T2352	T2356N	2356	Missense	distal	4	no	16.005	15.703	EPSD	ICGC;COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	P46013	MKI67	P24941	CDK2	T2455	T2460I	2460	Missense	distal	5	no	9.096	9.215	EPSD	ICGC;COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	P46013	MKI67	P24941	CDK2	T2455	T2460A	2460	Missense	distal	5	no	9.096	9.132	EPSD	ICGC;COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	P46013	MKI67	P24941	CDK2	S2466	T2460I	2460	Missense	distal	-6	no	13.789	13.791	EPSD	ICGC;COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	P46013	MKI67	P24941	CDK2	S2466	T2460A	2460	Missense	distal	-6	no	13.789	13.788	EPSD	ICGC;COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	P46013	MKI67	P24941	CDK2	S2528	D2534Y	2534	Missense	distal	6	no	12.355	12.362	EPSD	ICGC;COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	P46013	MKI67	P24941	CDK2	T2540	D2534Y	2534	Missense	distal	-6	no	8.151	8.153	EPSD	ICGC;COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	P46013	MKI67	P24941	CDK2	T2816	E2812D	2812	Missense	distal	-4	no	9.032	9.329	EPSD	ICGC;COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	Q9NS91	RAD18	P24941	CDK2	S99	P104H	104	Missense	distal	5	no	17.114	17.192	PhosphoSitePlus	ICGC;COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	Q9NS91	RAD18	P24941	CDK2	S103	P104H	104	Missense	proximal	1	no	12.281	5.523	EPSD	ICGC;COSMIC	8.148	Loss
CMGC_CDK_CDK2_CDK2_ST	Q9NS91	RAD18	P24941	CDK2	T118	L112F	112	Missense	distal	-6	no	13.363	13.367	EPSD	ICGC;COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	Q9NS91	RAD18	P24941	CDK2	T118	Q124K	124	Missense	distal	6	no	13.363	13.366	EPSD	ICGC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	Q9NS91	RAD18	P24941	CDK2	T118	T118N	118	Missense	central	0	yes	13.363	0.000	EPSD	ICGC	8.148	Loss
CMGC_CDK_CDK2_CDK2_ST	Q9NS91	RAD18	P24941	CDK2	S164	T169N	169	Missense	distal	5	no	14.922	15.051	EPSD	ICGC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	Q9NS91	RAD18	P24941	CDK2	S380	K376E	376	Missense	distal	-4	no	8.840	9.152	EPSD	ICGC;COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	Q9NS91	RAD18	P24941	CDK2	S380	L384Q	384	Missense	distal	4	no	8.840	8.790	EPSD	ICGC;COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	Q9NS91	RAD18	P24941	CDK2	S403	H401Q	401	Missense	proximal	-2	no	10.956	11.399	EPSD	ICGC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	Q9NS91	RAD18	P24941	CDK2	S409	P415T	415	Missense	distal	6	no	17.115	17.123	EPSD	ICGC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	Q9NS91	RAD18	P24941	CDK2	S409	E411D	411	Missense	proximal	2	no	17.115	17.015	EPSD	ICGC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	Q9NS91	RAD18	P24941	CDK2	S471	R476H	476	Missense	distal	5	no	15.137	15.108	EPSD	ICGC;COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	Q9NS91	RAD18	P24941	CDK2	S471	D464N	464	Missense	distal	-7	no	15.137	14.814	EPSD	ICGC;COSMIC;CCLE	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	Q9NS91	RAD18	P24941	CDK2	S471	Q474K	474	Missense	distal	3	no	15.137	17.869	EPSD	ICGC;COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	Q9NS91	RAD18	P24941	CDK2	S471	T478K	478	Missense	distal	7	no	15.137	15.154	EPSD	ICGC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	P26358	DNMT1	P24941	CDK2	S115	V120L	120	Missense	distal	5	no	8.525	8.598	EPSD	ICGC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	P26358	DNMT1	P24941	CDK2	S115	N111K	111	Missense	distal	-4	no	8.525	8.306	EPSD	ICGC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	P26358	DNMT1	P24941	CDK2	S127	V120L	120	Missense	distal	-7	no	14.636	14.622	EPSD	ICGC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	P26358	DNMT1	P24941	CDK2	T137	P138L	138	Missense	proximal	1	no	16.872	7.052	EPSD	ICGC;COSMIC	8.148	Loss
CMGC_CDK_CDK2_CDK2_ST	P26358	DNMT1	P24941	CDK2	T137	P135T	135	Missense	proximal	-2	no	16.872	16.839	EPSD	ICGC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	P26358	DNMT1	P24941	CDK2	T137	R139K	139	Missense	proximal	2	no	16.872	16.573	EPSD	ICGC;COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	P26358	DNMT1	P24941	CDK2	T137	R139S	139	Missense	proximal	2	no	16.872	16.780	EPSD	ICGC;COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	P26358	DNMT1	P24941	CDK2	T137	R136H	136	Missense	proximal	-1	no	16.872	16.421	EPSD	ICGC;COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	P26358	DNMT1	P24941	CDK2	S152	A147T	147	Missense	distal	-5	no	14.567	14.541	EPSD	ICGC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	P26358	DNMT1	P24941	CDK2	S154	A147T	147	Missense	distal	-7	no	13.641	13.474	PhosphoSitePlus	ICGC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	Q2NL82	TSR1	P24941	CDK2	T490	A496T	496	Missense	distal	6	no	15.273	15.285	PhosphoSitePlus	ICGC;COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	Q2NL82	TSR1	P24941	CDK2	T490	A495D	495	Missense	distal	5	no	15.273	15.437	PhosphoSitePlus	ICGC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	Q2NL82	TSR1	P24941	CDK2	S512	K507R	507	Missense	distal	-5	no	12.985	13.030	EPSD	ICGC;COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	Q2NL82	TSR1	P24941	CDK2	S512	T511K	511	Missense	proximal	-1	no	12.985	13.148	EPSD	ICGC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	Q2NL82	TSR1	P24941	CDK2	S626	R622H	622	Missense	distal	-4	no	12.660	12.299	EPSD	ICGC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	P22674	CCNO	P24941	CDK2	S8	A13T	13	Missense	distal	5	no	12.426	12.391	EPSD	ICGC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	P22674	CCNO	P24941	CDK2	S11	A13T	13	Missense	proximal	2	no	9.734	9.532	EPSD	ICGC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	P22674	CCNO	P24941	CDK2	S81	P84S	84	Missense	distal	3	no	16.985	17.019	PhosphoSitePlus	ICGC;COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	Q9P2B4	CTTNBP2NL	P24941	CDK2	S285	H281R	281	Missense	distal	-4	no	13.740	14.101	EPSD	ICGC;COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	Q9P2B4	CTTNBP2NL	P24941	CDK2	T340	G334W	334	Missense	distal	-6	no	10.277	10.282	EPSD	ICGC;COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	Q9P2B4	CTTNBP2NL	P24941	CDK2	T340	P336S	336	Missense	distal	-4	no	10.277	10.631	EPSD	ICGC;COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	Q9P2B4	CTTNBP2NL	P24941	CDK2	S430	S426C	426	Missense	distal	-4	no	13.445	12.339	EPSD	ICGC;COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	Q9P2B4	CTTNBP2NL	P24941	CDK2	S481	Q480R	480	Missense	proximal	-1	no	15.038	15.916	EPSD	ICGC;COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	Q9P2B4	CTTNBP2NL	P24941	CDK2	S488	P489R	489	Missense	proximal	1	no	13.683	3.885	EPSD	ICGC;COSMIC	8.148	Loss
CMGC_CDK_CDK2_CDK2_ST	Q9P2B4	CTTNBP2NL	P24941	CDK2	S488	T490I	490	Missense	proximal	2	no	13.683	13.838	EPSD	ICGC;COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	Q9P2B4	CTTNBP2NL	P24941	CDK2	T590	S594F	594	Missense	distal	4	no	12.047	11.851	EPSD	ICGC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	Q9P2B4	CTTNBP2NL	P24941	CDK2	T590	P593S	593	Missense	distal	3	no	12.047	12.081	EPSD	ICGC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	Q9P2B4	CTTNBP2NL	P24941	CDK2	T590	S592Y	592	Missense	proximal	2	no	12.047	12.038	EPSD	ICGC;COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	Q9P2B4	CTTNBP2NL	P24941	CDK2	S592	S594F	594	Missense	proximal	2	no	13.846	14.031	EPSD	ICGC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	Q9P2B4	CTTNBP2NL	P24941	CDK2	S592	P593S	593	Missense	proximal	1	no	13.846	2.581	EPSD	ICGC	8.148	Loss
CMGC_CDK_CDK2_CDK2_ST	Q9P2B4	CTTNBP2NL	P24941	CDK2	S592	S592Y	592	Missense	central	0	yes	13.846	0.000	EPSD	ICGC;COSMIC	8.148	Loss
CMGC_CDK_CDK2_CDK2_ST	Q9P2B4	CTTNBP2NL	P24941	CDK2	T597	S594F	594	Missense	distal	-3	no	13.582	13.673	EPSD	ICGC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	Q9P2B4	CTTNBP2NL	P24941	CDK2	T597	P593S	593	Missense	distal	-4	no	13.582	13.936	EPSD	ICGC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	Q9P2B4	CTTNBP2NL	P24941	CDK2	T597	S592Y	592	Missense	distal	-5	no	13.582	13.650	EPSD	ICGC;COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	O75616	ERAL1	P24941	CDK2	S53	F52L	52	Missense	proximal	-1	no	8.647	7.682	EPSD	ICGC;COSMIC	8.148	Loss
CMGC_CDK_CDK2_CDK2_ST	O75616	ERAL1	P24941	CDK2	S53	V47I	47	Missense	distal	-6	no	8.647	8.648	EPSD	ICGC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	O75616	ERAL1	P24941	CDK2	T168	Q162H	162	Missense	distal	-6	no	13.521	13.522	EPSD	ICGC;COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	O75616	ERAL1	P24941	CDK2	T168	G175D	175	Missense	distal	7	no	13.521	13.538	EPSD	ICGC;COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	O75616	ERAL1	P24941	CDK2	T168	T161I	161	Missense	distal	-7	no	13.521	13.718	EPSD	ICGC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	O75616	ERAL1	P24941	CDK2	T168	G170V	170	Missense	proximal	2	no	13.521	13.526	EPSD	ICGC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	O75616	ERAL1	P24941	CDK2	S173	G175D	175	Missense	proximal	2	no	17.645	17.525	PhosphoSitePlus	ICGC;COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	O75616	ERAL1	P24941	CDK2	S173	G170V	170	Missense	distal	-3	no	17.645	17.685	PhosphoSitePlus	ICGC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	O75616	ERAL1	P24941	CDK2	S216	L215F	215	Missense	proximal	-1	no	11.150	12.116	EPSD	ICGC;COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	P17096	HMGA1	P24941	CDK2	S36	A40V	40	Missense	distal	4	no	14.045	14.232	PhosphoSitePlus	ICGC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	P17096	HMGA1	P24941	CDK2	T53	G59V	59	Missense	distal	6	no	16.127	16.137	EPSD	ICGC;COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	P17096	HMGA1	P24941	CDK2	T53	E50K	50	Missense	distal	-3	no	16.127	15.912	EPSD	ICGC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	P17096	HMGA1	P24941	CDK2	T53	P48S	48	Missense	distal	-5	no	16.127	16.083	EPSD	ICGC;COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	P17096	HMGA1	P24941	CDK2	T78	K71N	71	Missense	distal	-7	no	15.071	15.037	EPSD	ICGC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	P38398	BRCA1	P24941	CDK2	S72	Q74K	74	Missense	proximal	2	no	8.317	8.117	EPSD	ICGC	8.148	Loss
CMGC_CDK_CDK2_CDK2_ST	P38398	BRCA1	P24941	CDK2	S114	D120G	120	Missense	distal	6	no	14.472	14.476	EPSD	ICGC;COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	P38398	BRCA1	P24941	CDK2	S114	H117N	117	Missense	distal	3	no	14.472	12.887	EPSD	ICGC;COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	P38398	BRCA1	P24941	CDK2	T208	G211K	211	Missense	distal	3	no	11.288	14.096	EPSD	ICGC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	P38398	BRCA1	P24941	CDK2	T208	R213S	213	Missense	distal	5	no	11.288	11.081	EPSD	ICGC;COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	P38398	BRCA1	P24941	CDK2	T208	P209H	209	Missense	proximal	1	no	11.288	4.529	EPSD	ICGC;COSMIC	8.148	Loss
CMGC_CDK_CDK2_CDK2_ST	P38398	BRCA1	P24941	CDK2	T231	D232H	232	Missense	proximal	1	no	6.876	8.361	EPSD	ICGC	8.148	Gain
CMGC_CDK_CDK2_CDK2_ST	P38398	BRCA1	P24941	CDK2	S510	R507T	507	Missense	distal	-3	no	9.362	9.134	EPSD	ICGC;COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	P38398	BRCA1	P24941	CDK2	S632	N635K	635	Missense	distal	3	no	8.616	11.886	EPSD	ICGC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	P38398	BRCA1	P24941	CDK2	S1191	H1197N	1197	Missense	distal	6	no	13.683	13.692	EPSD	ICGC;COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	Q9H1E3	NUCKS1	P24941	CDK2	S40	R42Q	42	Missense	proximal	2	no	13.456	13.356	EPSD	ICGC;COSMIC;CCLE	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	Q9H1E3	NUCKS1	P24941	CDK2	S40	P33L	33	Missense	distal	-7	no	13.456	13.462	EPSD	ICGC;COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	Q9H1E3	NUCKS1	P24941	CDK2	S50	R49Q	49	Missense	proximal	-1	no	8.399	7.521	EPSD	ICGC	8.148	Loss
CMGC_CDK_CDK2_CDK2_ST	Q9H1E3	NUCKS1	P24941	CDK2	S50	S54L	54	Missense	distal	4	no	8.399	8.498	EPSD	ICGC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	Q9H1E3	NUCKS1	P24941	CDK2	S61	D60E	60	Missense	proximal	-1	no	8.120	8.150	EPSD	ICGC	8.148	Gain
CMGC_CDK_CDK2_CDK2_ST	Q9H1E3	NUCKS1	P24941	CDK2	S61	S54L	54	Missense	distal	-7	no	8.120	8.306	EPSD	ICGC	8.148	Gain
CMGC_CDK_CDK2_CDK2_ST	Q9H1E3	NUCKS1	P24941	CDK2	S148	S149T	149	Missense	proximal	1	no	7.108	8.417	EPSD	ICGC;COSMIC	8.148	Gain
CMGC_CDK_CDK2_CDK2_ST	Q9H1E3	NUCKS1	P24941	CDK2	T202	S198A	198	Missense	distal	-4	no	11.962	11.549	EPSD	ICGC;COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	Q9H1E3	NUCKS1	P24941	CDK2	S214	P212T	212	Missense	proximal	-2	no	15.974	15.941	EPSD	ICGC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	Q9H1E3	NUCKS1	P24941	CDK2	S223	S229C	229	Missense	distal	6	no	15.342	15.327	EPSD	ICGC;COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	Q9UQ80	PA2G4	P24941	CDK2	S90	N83S	83	Missense	distal	-7	no	21.060	20.962	EPSD	ICGC;COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	Q9UQ80	PA2G4	P24941	CDK2	T180	F177Y	177	Missense	distal	-3	no	13.872	13.800	EPSD	ICGC;COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	Q9UQ80	PA2G4	P24941	CDK2	S267	E268G	268	Missense	proximal	1	no	6.669	8.522	EPSD	ICGC;COSMIC	8.148	Gain
CMGC_CDK_CDK2_CDK2_ST	Q9H3D4	TP63	P24941	CDK2	S160	S154F	154	Missense	distal	-6	no	12.081	12.086	EPSD	ICGC;COSMIC;GDSC;CCLE	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	Q9H3D4	TP63	P24941	CDK2	S160	P166S	166	Missense	distal	6	no	12.081	12.082	EPSD	ICGC;COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	Q9H3D4	TP63	P24941	CDK2	S160	P161A	161	Missense	proximal	1	no	12.081	-2.322	EPSD	ICGC	8.148	Loss
CMGC_CDK_CDK2_CDK2_ST	Q9H3D4	TP63	P24941	CDK2	S160	P161Q	161	Missense	proximal	1	no	12.081	4.169	EPSD	ICGC;COSMIC	8.148	Loss
CMGC_CDK_CDK2_CDK2_ST	Q9H3D4	TP63	P24941	CDK2	S160	S162L	162	Missense	proximal	2	no	12.081	11.908	EPSD	ICGC;COSMIC;GDSC;CCLE	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	Q9H3D4	TP63	P24941	CDK2	S160	I165T	165	Missense	distal	5	no	12.081	11.963	EPSD	ICGC;COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	Q9H3D4	TP63	P24941	CDK2	S160	D157N	157	Missense	distal	-3	no	12.081	12.037	EPSD	ICGC;COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	Q9H3D4	TP63	P24941	CDK2	S162	P166S	166	Missense	distal	4	no	10.982	10.996	EPSD	ICGC;COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	Q9H3D4	TP63	P24941	CDK2	S162	P161A	161	Missense	proximal	-1	no	10.982	10.712	EPSD	ICGC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	Q9H3D4	TP63	P24941	CDK2	S162	P161Q	161	Missense	proximal	-1	no	10.982	10.675	EPSD	ICGC;COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	Q9H3D4	TP63	P24941	CDK2	S162	S162L	162	Missense	central	0	yes	10.982	0.000	EPSD	ICGC;COSMIC;GDSC;CCLE	8.148	Loss
CMGC_CDK_CDK2_CDK2_ST	Q9H3D4	TP63	P24941	CDK2	S162	I165T	165	Missense	distal	3	no	10.982	11.536	EPSD	ICGC;COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	Q9H3D4	TP63	P24941	CDK2	S162	D157N	157	Missense	distal	-5	no	10.982	10.944	EPSD	ICGC;COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	Q9H3D4	TP63	P24941	CDK2	S395	R393C	393	Missense	proximal	-2	no	10.892	11.066	EPSD	ICGC;COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	Q9H3D4	TP63	P24941	CDK2	S395	R393S	393	Missense	proximal	-2	no	10.892	11.477	EPSD	ICGC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	Q9H3D4	TP63	P24941	CDK2	S395	R393H	393	Missense	proximal	-2	no	10.892	11.118	EPSD	ICGC;COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	Q9H3D4	TP63	P24941	CDK2	S395	T388P	388	Missense	distal	-7	no	10.892	10.895	EPSD	ICGC;COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	O75152	ZC3H11A	P24941	CDK2	S132	R136Q	136	Missense	distal	4	no	13.991	14.172	EPSD	ICGC;COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	O75152	ZC3H11A	P24941	CDK2	S132	V127F	127	Missense	distal	-5	no	13.991	14.032	EPSD	ICGC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	O75152	ZC3H11A	P24941	CDK2	S132	V138F	138	Missense	distal	6	no	13.991	13.974	EPSD	ICGC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	O75152	ZC3H11A	P24941	CDK2	S132	P133T	133	Missense	proximal	1	no	13.991	4.033	EPSD	ICGC	8.148	Loss
CMGC_CDK_CDK2_CDK2_ST	O75152	ZC3H11A	P24941	CDK2	S132	R136W	136	Missense	distal	4	no	13.991	13.631	EPSD	ICGC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	O75152	ZC3H11A	P24941	CDK2	S149	T151K	151	Missense	proximal	2	no	15.255	15.292	EPSD	ICGC;COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	O75152	ZC3H11A	P24941	CDK2	S149	V147F	147	Missense	proximal	-2	no	15.255	14.792	EPSD	ICGC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	O75152	ZC3H11A	P24941	CDK2	S149	P148S	148	Missense	proximal	-1	no	15.255	14.784	EPSD	ICGC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	O75152	ZC3H11A	P24941	CDK2	T179	E172D	172	Missense	distal	-7	no	11.614	11.765	EPSD	ICGC;COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	O75152	ZC3H11A	P24941	CDK2	S495	P496S	496	Missense	proximal	1	no	12.509	1.243	EPSD	ICGC;COSMIC	8.148	Loss
CMGC_CDK_CDK2_CDK2_ST	O75152	ZC3H11A	P24941	CDK2	T502	P496S	496	Missense	distal	-6	no	11.820	11.819	EPSD	ICGC;COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	O75152	ZC3H11A	P24941	CDK2	T502	P503S	503	Missense	proximal	1	no	11.820	0.554	EPSD	ICGC	8.148	Loss
CMGC_CDK_CDK2_CDK2_ST	O75152	ZC3H11A	P24941	CDK2	T515	E519K	519	Missense	distal	4	no	8.760	9.145	EPSD	ICGC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	O75152	ZC3H11A	P24941	CDK2	S663	P664L	664	Missense	proximal	1	no	11.007	1.186	EPSD	ICGC;COSMIC	8.148	Loss
CMGC_CDK_CDK2_CDK2_ST	O75152	ZC3H11A	P24941	CDK2	S663	V658F	658	Missense	distal	-5	no	11.007	11.048	EPSD	ICGC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	O75152	ZC3H11A	P24941	CDK2	S663	P668Q	668	Missense	distal	5	no	11.007	10.967	EPSD	ICGC;COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	Q8IXJ6	SIRT2	P24941	CDK2	S25	A32T	32	Missense	distal	7	no	9.646	8.957	EPSD	ICGC;COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	Q8IXJ6	SIRT2	P24941	CDK2	S193	V196I	196	Missense	distal	3	no	10.259	8.983	EPSD	ICGC;COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	Q8IXJ6	SIRT2	P24941	CDK2	T280	L278F	278	Missense	proximal	-2	no	14.094	13.206	EPSD	ICGC;COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	Q8IXJ6	SIRT2	P24941	CDK2	S368	P375H	375	Missense	distal	7	no	15.904	16.035	PhosphoSitePlus;EPSD	ICGC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	Q8IXJ6	SIRT2	P24941	CDK2	S368	P373T	373	Missense	distal	5	no	15.904	15.878	PhosphoSitePlus;EPSD	ICGC;COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	Q8IXJ6	SIRT2	P24941	CDK2	S368	K370N	370	Missense	proximal	2	no	15.904	15.974	PhosphoSitePlus;EPSD	ICGC;COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	Q8IXJ6	SIRT2	P24941	CDK2	S372	P375H	375	Missense	distal	3	no	14.855	15.877	EPSD	ICGC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	Q8IXJ6	SIRT2	P24941	CDK2	S372	P373T	373	Missense	proximal	1	no	14.855	4.897	EPSD	ICGC;COSMIC	8.148	Loss
CMGC_CDK_CDK2_CDK2_ST	Q8IXJ6	SIRT2	P24941	CDK2	S372	K370N	370	Missense	proximal	-2	no	14.855	14.026	EPSD	ICGC;COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	P55795	HNRNPH2	P24941	CDK2	S104	P102L	102	Missense	proximal	-2	no	14.520	14.296	PhosphoSitePlus	ICGC;COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	P55795	HNRNPH2	P24941	CDK2	S104	P105H	105	Missense	proximal	1	no	14.520	7.762	PhosphoSitePlus	ICGC;COSMIC	8.148	Loss
CMGC_CDK_CDK2_CDK2_ST	P55795	HNRNPH2	P24941	CDK2	S104	P102Q	102	Missense	proximal	-2	no	14.520	13.953	PhosphoSitePlus	ICGC;COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	P55795	HNRNPH2	P24941	CDK2	S272	Y266D	266	Missense	distal	-6	no	8.567	8.566	EPSD	ICGC;COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	P55795	HNRNPH2	P24941	CDK2	S272	G270E	270	Missense	proximal	-2	no	8.567	8.194	EPSD	ICGC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	P55795	HNRNPH2	P24941	CDK2	S310	N307D	307	Missense	distal	-3	no	14.756	14.800	EPSD	ICGC;COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	Q9P270	SLAIN2	P24941	CDK2	S81	R85L	85	Missense	distal	4	no	10.180	10.412	EPSD	ICGC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	Q9P270	SLAIN2	P24941	CDK2	S81	G80E	80	Missense	proximal	-1	no	10.180	9.916	EPSD	ICGC;COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	Q9P270	SLAIN2	P24941	CDK2	S134	P141L	141	Missense	distal	7	no	14.737	14.768	EPSD	ICGC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	Q9P270	SLAIN2	P24941	CDK2	T140	M142I	142	Missense	proximal	2	no	12.481	12.247	EPSD	ICGC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	Q9P270	SLAIN2	P24941	CDK2	T140	P141L	141	Missense	proximal	1	no	12.481	2.660	EPSD	ICGC	8.148	Loss
CMGC_CDK_CDK2_CDK2_ST	Q9P270	SLAIN2	P24941	CDK2	S147	M142I	142	Missense	distal	-5	no	14.293	14.225	EPSD	ICGC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	Q9P270	SLAIN2	P24941	CDK2	S160	V163A	163	Missense	distal	3	no	14.890	13.769	EPSD	ICGC;COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	Q9P270	SLAIN2	P24941	CDK2	S160	S160R	160	Missense	central	0	yes	14.890	0.000	EPSD	ICGC;COSMIC	8.148	Loss
CMGC_CDK_CDK2_CDK2_ST	Q9P270	SLAIN2	P24941	CDK2	S160	S160L	160	Missense	central	0	yes	14.890	0.000	EPSD	ICGC;COSMIC	8.148	Loss
CMGC_CDK_CDK2_CDK2_ST	Q9P270	SLAIN2	P24941	CDK2	S160	P159L	159	Missense	proximal	-1	no	14.890	14.710	EPSD	ICGC;COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	Q9P270	SLAIN2	P24941	CDK2	S214	S209N	209	Missense	distal	-5	no	15.242	15.306	EPSD	ICGC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	Q9P270	SLAIN2	P24941	CDK2	S214	S209I	209	Missense	distal	-5	no	15.242	15.326	EPSD	ICGC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	Q9P270	SLAIN2	P24941	CDK2	S343	P337A	337	Missense	distal	-6	no	14.013	14.011	EPSD	ICGC;COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	Q9P270	SLAIN2	P24941	CDK2	S377	R384C	384	Missense	distal	7	no	15.717	15.869	EPSD	ICGC;COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	Q9P270	SLAIN2	P24941	CDK2	S377	R384H	384	Missense	distal	7	no	15.717	15.359	EPSD	ICGC;COSMIC;GDSC;CCLE	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	Q13309	SKP2	P24941	CDK2	S64	L70P	70	Missense	distal	6	no	15.360	15.359	PhosphoSitePlus	ICGC;COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	Q13309	SKP2	P24941	CDK2	S64	P62Q	62	Missense	proximal	-2	no	15.360	14.793	PhosphoSitePlus	ICGC;COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	Q13309	SKP2	P24941	CDK2	S179	F178L	178	Missense	proximal	-1	no	17.503	16.538	EPSD	ICGC;COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	Q13309	SKP2	P24941	CDK2	S179	H185R	185	Missense	distal	6	no	17.503	17.492	EPSD	ICGC;COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	P04637	TP53	P24941	CDK2	S33	P34L	34	Missense	proximal	1	no	15.549	5.728	EPSD	ICGC;COSMIC	8.148	Loss
CMGC_CDK_CDK2_CDK2_ST	P04637	TP53	P24941	CDK2	S33	S33F	33	Missense	central	0	yes	15.549	0.000	EPSD	ICGC;COSMIC	8.148	Loss
CMGC_CDK_CDK2_CDK2_ST	P04637	TP53	P24941	CDK2	S33	N30I	30	Missense	distal	-3	no	15.549	15.548	EPSD	ICGC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	P04637	TP53	P24941	CDK2	S37	P34L	34	Missense	distal	-3	no	9.176	9.105	EPSD	ICGC;COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	P04637	TP53	P24941	CDK2	S37	S33F	33	Missense	distal	-4	no	9.176	8.214	EPSD	ICGC;COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	P04637	TP53	P24941	CDK2	S37	N30I	30	Missense	distal	-7	no	9.176	9.452	EPSD	ICGC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	P04637	TP53	P24941	CDK2	S46	D48G	48	Missense	proximal	2	no	14.212	14.332	EPSD	ICGC;COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	P04637	TP53	P24941	CDK2	S46	Q52K	52	Missense	distal	6	no	14.212	14.215	EPSD	ICGC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	P04637	TP53	P24941	CDK2	T81	A88D	88	Missense	distal	7	no	14.045	14.347	EPSD	ICGC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	P04637	TP53	P24941	CDK2	T81	P87Q	87	Missense	distal	6	no	14.045	14.051	EPSD	ICGC;COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	P04637	TP53	P24941	CDK2	S127	T125R	125	Missense	proximal	-2	no	15.119	13.917	EPSD	ICGC;COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	P04637	TP53	P24941	CDK2	S127	F134C	134	Missense	distal	7	no	15.119	15.059	EPSD	ICGC;COSMIC;CCLE	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	P04637	TP53	P24941	CDK2	S127	C124G	124	Missense	distal	-3	no	15.119	15.120	EPSD	ICGC;COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	P04637	TP53	P24941	CDK2	S127	C124R	124	Missense	distal	-3	no	15.119	15.205	EPSD	ICGC;COSMIC;GDSC;CCLE	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	P04637	TP53	P24941	CDK2	S127	L130H	130	Missense	distal	3	no	15.119	16.525	EPSD	ICGC;COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	P04637	TP53	P24941	CDK2	S127	T125A	125	Missense	proximal	-2	no	15.119	15.169	EPSD	ICGC;COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	P04637	TP53	P24941	CDK2	S127	K120N	120	Missense	distal	-7	no	15.119	15.085	EPSD	ICGC;COSMIC;GDSC;CCLE	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	P04637	TP53	P24941	CDK2	S127	N131Y	131	Missense	distal	4	no	15.119	15.339	EPSD	ICGC;COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	P04637	TP53	P24941	CDK2	S127	K120M	120	Missense	distal	-7	no	15.119	15.668	EPSD	ICGC;COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	P04637	TP53	P24941	CDK2	S127	K132M	132	Missense	distal	5	no	15.119	15.481	EPSD	ICGC;COSMIC;CCLE	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	P04637	TP53	P24941	CDK2	S127	M133T	133	Missense	distal	6	no	15.119	15.146	EPSD	ICGC;COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	P04637	TP53	P24941	CDK2	S127	K120R	120	Missense	distal	-7	no	15.119	15.510	EPSD	ICGC;COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	P04637	TP53	P24941	CDK2	S127	C124Y	124	Missense	distal	-3	no	15.119	15.131	EPSD	ICGC;COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	P04637	TP53	P24941	CDK2	T150	R156L	156	Missense	distal	6	no	10.420	10.438	EPSD	ICGC;COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	P04637	TP53	P24941	CDK2	T150	L145Q	145	Missense	distal	-5	no	10.420	10.409	EPSD	ICGC;COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	P04637	TP53	P24941	CDK2	T150	P152R	152	Missense	proximal	2	no	10.420	10.579	EPSD	ICGC;COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	P04637	TP53	P24941	CDK2	T150	G154S	154	Missense	distal	4	no	10.420	10.554	EPSD	ICGC;COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	P04637	TP53	P24941	CDK2	T150	V157A	157	Missense	distal	7	no	10.420	10.547	EPSD	ICGC;COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	P04637	TP53	P24941	CDK2	T150	P151F	151	Missense	proximal	1	no	10.420	-4.390	EPSD	ICGC;COSMIC	8.148	Loss
CMGC_CDK_CDK2_CDK2_ST	P04637	TP53	P24941	CDK2	T150	V147G	147	Missense	distal	-3	no	10.420	10.381	EPSD	ICGC;COSMIC;GDSC;CCLE	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	P04637	TP53	P24941	CDK2	S315	T312I	312	Missense	distal	-3	no	14.293	14.352	PhosphoSitePlus	ICGC;COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	P04637	TP53	P24941	CDK2	S315	P322T	322	Missense	distal	7	no	14.293	13.989	PhosphoSitePlus	ICGC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	P04637	TP53	P24941	CDK2	S367	G374C	374	Missense	distal	7	no	8.674	8.645	EPSD	ICGC;COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	P04637	TP53	P24941	CDK2	S376	T377P	377	Missense	proximal	1	no	6.508	16.465	EPSD	ICGC;COSMIC	8.148	Gain
CMGC_CDK_CDK2_CDK2_ST	Q9C0D5	TANC1	P24941	CDK2	S29	P30S	30	Missense	proximal	1	no	12.404	1.138	EPSD	ICGC;COSMIC	8.148	Loss
CMGC_CDK_CDK2_CDK2_ST	Q9C0D5	TANC1	P24941	CDK2	S40	P46L	46	Missense	distal	6	no	13.681	13.683	EPSD	ICGC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	Q9C0D5	TANC1	P24941	CDK2	S85	S85Y	85	Missense	central	0	yes	13.901	0.000	EPSD	ICGC;COSMIC	8.148	Loss
CMGC_CDK_CDK2_CDK2_ST	Q9C0D5	TANC1	P24941	CDK2	S132	P129L	129	Missense	distal	-3	no	12.632	12.561	EPSD	ICGC;COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	Q9C0D5	TANC1	P24941	CDK2	S132	P129A	129	Missense	distal	-3	no	12.632	12.573	EPSD	ICGC;COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	Q9C0D5	TANC1	P24941	CDK2	S174	T178I	178	Missense	distal	4	no	12.827	12.516	EPSD	ICGC;COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	Q9C0D5	TANC1	P24941	CDK2	S185	C192F	192	Missense	distal	7	no	13.043	13.104	EPSD	ICGC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	Q9C0D5	TANC1	P24941	CDK2	S185	T178I	178	Missense	distal	-7	no	13.043	13.240	EPSD	ICGC;COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	Q9C0D5	TANC1	P24941	CDK2	S207	K206T	206	Missense	proximal	-1	no	11.520	11.357	EPSD	ICGC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	Q9C0D5	TANC1	P24941	CDK2	S214	S217Y	217	Missense	distal	3	no	12.466	11.686	EPSD	ICGC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	Q9C0D5	TANC1	P24941	CDK2	S214	S217T	217	Missense	distal	3	no	12.466	12.317	EPSD	ICGC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	Q9C0D5	TANC1	P24941	CDK2	S214	S216T	216	Missense	proximal	2	no	12.466	12.222	EPSD	ICGC;COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	Q9C0D5	TANC1	P24941	CDK2	S240	G241D	241	Missense	proximal	1	no	8.777	7.846	EPSD	ICGC;COSMIC	8.148	Loss
CMGC_CDK_CDK2_CDK2_ST	Q9C0D5	TANC1	P24941	CDK2	S270	E275Q	275	Missense	distal	5	no	13.080	12.961	EPSD	ICGC;COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	Q9C0D5	TANC1	P24941	CDK2	S444	G446V	446	Missense	proximal	2	no	14.217	14.222	EPSD	ICGC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	Q9C0D5	TANC1	P24941	CDK2	S444	S447T	447	Missense	distal	3	no	14.217	14.069	EPSD	ICGC;COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	Q9C0D5	TANC1	P24941	CDK2	S448	G446V	446	Missense	proximal	-2	no	11.399	11.491	EPSD	ICGC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	Q9C0D5	TANC1	P24941	CDK2	S448	S447T	447	Missense	proximal	-1	no	11.399	11.606	EPSD	ICGC;COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	Q9C0D5	TANC1	P24941	CDK2	T461	F460L	460	Missense	proximal	-1	no	14.436	13.471	EPSD	ICGC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	Q9C0D5	TANC1	P24941	CDK2	T461	L463F	463	Missense	proximal	2	no	14.436	14.794	EPSD	ICGC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	Q9C0D5	TANC1	P24941	CDK2	T461	S465L	465	Missense	distal	4	no	14.436	14.535	EPSD	ICGC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	Q9C0D5	TANC1	P24941	CDK2	S465	F460L	460	Missense	distal	-5	no	14.984	14.924	EPSD	ICGC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	Q9C0D5	TANC1	P24941	CDK2	S465	L463F	463	Missense	proximal	-2	no	14.984	14.095	EPSD	ICGC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	Q9C0D5	TANC1	P24941	CDK2	S465	S465L	465	Missense	central	0	yes	14.984	0.000	EPSD	ICGC	8.148	Loss
CMGC_CDK_CDK2_CDK2_ST	Q9C0D5	TANC1	P24941	CDK2	S474	S473F	473	Missense	proximal	-1	no	7.956	9.213	EPSD	ICGC;COSMIC	8.148	Gain
CMGC_CDK_CDK2_CDK2_ST	Q9C0D5	TANC1	P24941	CDK2	T478	S473F	473	Missense	distal	-5	no	14.736	14.852	EPSD	ICGC;COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	Q9C0D5	TANC1	P24941	CDK2	T478	L480I	480	Missense	proximal	2	no	14.736	14.820	EPSD	ICGC;COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	Q9C0D5	TANC1	P24941	CDK2	T910	N907D	907	Missense	distal	-3	no	14.257	14.301	EPSD	ICGC;COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	Q9C0D5	TANC1	P24941	CDK2	T910	S904F	904	Missense	distal	-6	no	14.257	14.262	EPSD	ICGC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	Q9C0D5	TANC1	P24941	CDK2	T1147	A1152S	1152	Missense	distal	5	no	12.183	12.072	EPSD	ICGC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	Q9C0D5	TANC1	P24941	CDK2	T1147	G1145C	1145	Missense	proximal	-2	no	12.183	11.864	EPSD	ICGC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	Q9C0D5	TANC1	P24941	CDK2	T1445	G1449V	1449	Missense	distal	4	no	13.836	14.182	EPSD	ICGC;COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	Q9C0D5	TANC1	P24941	CDK2	T1447	G1449V	1449	Missense	proximal	2	no	13.855	13.860	EPSD	ICGC;COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	Q9C0D5	TANC1	P24941	CDK2	S1503	S1506I	1506	Missense	distal	3	no	13.796	13.094	EPSD	ICGC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	Q9C0D5	TANC1	P24941	CDK2	T1573	T1573A	1573	Missense	central	0	yes	15.927	0.000	EPSD	ICGC;COSMIC	8.148	Loss
CMGC_CDK_CDK2_CDK2_ST	Q9C0D5	TANC1	P24941	CDK2	T1573	R1578I	1578	Missense	distal	5	no	15.927	15.913	EPSD	ICGC;COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	Q9C0D5	TANC1	P24941	CDK2	S1632	R1629G	1629	Missense	distal	-3	no	10.226	10.141	EPSD	ICGC;COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	Q9C0D5	TANC1	P24941	CDK2	S1632	V1636L	1636	Missense	distal	4	no	10.226	10.111	EPSD	ICGC;COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	Q9C0D5	TANC1	P24941	CDK2	S1632	R1629M	1629	Missense	distal	-3	no	10.226	10.406	EPSD	ICGC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	Q9C0D5	TANC1	P24941	CDK2	S1632	A1637D	1637	Missense	distal	5	no	10.226	10.390	EPSD	ICGC;COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	Q9C0D5	TANC1	P24941	CDK2	S1632	V1638L	1638	Missense	distal	6	no	10.226	10.229	EPSD	ICGC;COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	Q9C0D5	TANC1	P24941	CDK2	S1668	S1662G	1662	Missense	distal	-6	no	13.364	13.367	EPSD	ICGC;COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	Q9C0D5	TANC1	P24941	CDK2	T1707	Q1710H	1710	Missense	distal	3	no	7.558	8.605	EPSD	ICGC	8.148	Gain
CMGC_CDK_CDK2_CDK2_ST	Q9C0D5	TANC1	P24941	CDK2	T1721	G1725C	1725	Missense	distal	4	no	10.690	10.062	EPSD	ICGC;COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	Q9C0D5	TANC1	P24941	CDK2	T1721	M1724I	1724	Missense	distal	3	no	10.690	10.262	EPSD	ICGC;COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	Q9C0D5	TANC1	P24941	CDK2	T1721	G1725V	1725	Missense	distal	4	no	10.690	11.036	EPSD	ICGC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	P51649	ALDH5A1	P24941	CDK2	T181	H180Y	180	Missense	proximal	-1	no	19.210	19.529	PhosphoSitePlus	ICGC;COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	P51649	ALDH5A1	P24941	CDK2	T181	P182L	182	Missense	proximal	1	no	19.210	9.389	PhosphoSitePlus	ICGC;COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	Q5JTV8	TOR1AIP1	P24941	CDK2	T20	A23S	23	Missense	distal	3	no	12.521	13.067	EPSD	ICGC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	Q5JTV8	TOR1AIP1	P24941	CDK2	T20	P24A	24	Missense	distal	4	no	12.521	12.560	EPSD	ICGC;COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	Q5JTV8	TOR1AIP1	P24941	CDK2	S143	V145G	145	Missense	proximal	2	no	14.622	14.617	PhosphoSitePlus	ICGC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	Q5JTV8	TOR1AIP1	P24941	CDK2	S143	M146T	146	Missense	distal	3	no	14.622	14.748	PhosphoSitePlus	ICGC;COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	Q5JTV8	TOR1AIP1	P24941	CDK2	S228	S231I	231	Missense	distal	3	no	9.722	9.020	EPSD	ICGC;COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	Q5JTV8	TOR1AIP1	P24941	CDK2	S228	E222K	222	Missense	distal	-6	no	9.722	9.719	EPSD	ICGC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	Q8TAP6	CEP76	P24941	CDK2	T335	A340E	340	Missense	distal	5	no	17.340	17.409	EPSD	ICGC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	Q8TAP6	CEP76	P24941	CDK2	T335	T335N	335	Missense	central	0	yes	17.340	0.000	EPSD	ICGC	8.148	Loss
Atypical_Alpha_eEF2K_EEF2K_ST	O00418	EEF2K	O00418	EEF2K	S48	N53S	53	Missense	distal	5	no	50.003	58.355	EPSD	ICGC;COSMIC	53.998	Gain
Atypical_Alpha_eEF2K_EEF2K_ST	O00418	EEF2K	O00418	EEF2K	S71	P75A	75	Missense	distal	4	no	59.038	58.670	EPSD	ICGC;COSMIC	53.998	Down-regulation
Atypical_Alpha_eEF2K_EEF2K_ST	O00418	EEF2K	O00418	EEF2K	S71	P75L	75	Missense	distal	4	no	59.038	61.839	EPSD	ICGC;COSMIC	53.998	Up-regulation
Atypical_Alpha_eEF2K_EEF2K_ST	O00418	EEF2K	O00418	EEF2K	S71	S71F	71	Missense	central	0	yes	59.038	0.000	EPSD	ICGC;COSMIC	53.998	Loss
Atypical_Alpha_eEF2K_EEF2K_ST	O00418	EEF2K	O00418	EEF2K	S71	S66R	66	Missense	distal	-5	no	59.038	58.894	EPSD	ICGC	53.998	Down-regulation
Atypical_Alpha_eEF2K_EEF2K_ST	O00418	EEF2K	O00418	EEF2K	T348	K347N	347	Missense	proximal	-1	no	105.565	105.461	EPSD;PhosphoSitePlus	ICGC;COSMIC	53.998	Down-regulation
Atypical_Alpha_eEF2K_EEF2K_ST	O00418	EEF2K	O00418	EEF2K	T353	K347N	347	Missense	distal	-6	no	92.253	93.410	EPSD;PhosphoSitePlus	ICGC;COSMIC	53.998	Up-regulation
Atypical_Alpha_eEF2K_EEF2K_ST	O00418	EEF2K	O00418	EEF2K	T353	P360L	360	Missense	distal	7	no	92.253	87.132	EPSD;PhosphoSitePlus	ICGC	53.998	Down-regulation
Atypical_Alpha_eEF2K_EEF2K_ST	O00418	EEF2K	O00418	EEF2K	S366	R369W	369	Missense	distal	3	no	100.807	82.235	EPSD;PhosphoSitePlus	ICGC	53.998	Down-regulation
Atypical_Alpha_eEF2K_EEF2K_ST	O00418	EEF2K	O00418	EEF2K	S366	Q361R	361	Missense	distal	-5	no	100.807	100.596	EPSD;PhosphoSitePlus	ICGC	53.998	Down-regulation
Atypical_Alpha_eEF2K_EEF2K_ST	O00418	EEF2K	O00418	EEF2K	S366	P360L	360	Missense	distal	-6	no	100.807	104.516	EPSD;PhosphoSitePlus	ICGC	53.998	Up-regulation
Atypical_Alpha_eEF2K_EEF2K_ST	O00418	EEF2K	O00418	EEF2K	S441	R448L	448	Missense	distal	7	no	90.329	83.178	EPSD;PhosphoSitePlus	ICGC;COSMIC	53.998	Down-regulation
Atypical_Alpha_eEF2K_EEF2K_ST	O00418	EEF2K	O00418	EEF2K	S441	E436D	436	Missense	distal	-5	no	90.329	89.670	EPSD;PhosphoSitePlus	ICGC;COSMIC	53.998	Down-regulation
Atypical_Alpha_eEF2K_EEF2K_ST	O00418	EEF2K	O00418	EEF2K	S441	S438I	438	Missense	distal	-3	no	90.329	93.964	EPSD;PhosphoSitePlus	ICGC	53.998	Up-regulation
Atypical_Alpha_eEF2K_EEF2K_ST	O00418	EEF2K	O00418	EEF2K	S445	R448L	448	Missense	distal	3	no	106.516	80.524	EPSD;PhosphoSitePlus	ICGC;COSMIC	53.998	Down-regulation
Atypical_Alpha_eEF2K_EEF2K_ST	O00418	EEF2K	O00418	EEF2K	S445	S438I	438	Missense	distal	-7	no	106.516	89.096	EPSD;PhosphoSitePlus	ICGC	53.998	Down-regulation
Atypical_Alpha_eEF2K_EEF2K_ST	O00418	EEF2K	O00418	EEF2K	S464	R466W	466	Missense	proximal	2	no	53.420	55.145	EPSD	ICGC;COSMIC	53.998	Gain
Atypical_Alpha_eEF2K_EEF2K_ST	O00418	EEF2K	O00418	EEF2K	S474	D471Y	471	Missense	distal	-3	no	112.113	113.722	EPSD;PhosphoSitePlus	ICGC	53.998	Up-regulation
AGC_PKG_PRKG1_ST	P50552	VASP	Q13976	PRKG1	S157	A164S	164	Missense	distal	7	no	13.230	13.252	EPSD;PhosphoSitePlus	ICGC	7.092	Up-regulation
AGC_PKG_PRKG1_ST	P50552	VASP	Q13976	PRKG1	S157	V156F	156	Missense	proximal	-1	no	13.230	13.250	EPSD;PhosphoSitePlus	ICGC	7.092	Up-regulation
AGC_PKG_PRKG1_ST	P50552	VASP	Q13976	PRKG1	S157	I152M	152	Missense	distal	-5	no	13.230	13.024	EPSD;PhosphoSitePlus	ICGC;COSMIC	7.092	Down-regulation
AGC_PKG_PRKG1_ST	P50552	VASP	Q13976	PRKG1	S157	S157Y	157	Missense	central	0	yes	13.230	0.000	EPSD;PhosphoSitePlus	ICGC;COSMIC	7.092	Loss
AGC_PKG_PRKG1_ST	P50552	VASP	Q13976	PRKG1	T278	P285H	285	Missense	distal	7	no	9.874	9.932	EPSD;PhosphoSitePlus	ICGC;COSMIC	7.092	Up-regulation
AGC_PKG_PRKG1_ST	P50552	VASP	Q13976	PRKG1	T278	G281V	281	Missense	distal	3	no	9.874	9.939	EPSD;PhosphoSitePlus	ICGC;COSMIC	7.092	Up-regulation
AGC_PKG_PRKG1_ST	P50552	VASP	Q13976	PRKG1	S305	P300Q	300	Missense	distal	-5	no	8.159	8.025	EPSD	ICGC;COSMIC	7.092	Down-regulation
AGC_PKG_PRKG1_ST	P50552	VASP	Q13976	PRKG1	S314	K321N	321	Missense	distal	7	no	7.455	7.400	EPSD	ICGC	7.092	Down-regulation
AGC_PKG_PRKG1_ST	P50552	VASP	Q13976	PRKG1	S322	K321N	321	Missense	proximal	-1	no	11.110	10.983	EPSD	ICGC	7.092	Down-regulation
AGC_PKG_PRKG1_ST	P50552	VASP	Q13976	PRKG1	S323	K321N	321	Missense	proximal	-2	no	8.265	5.321	EPSD	ICGC	7.092	Loss
AGC_PKG_PRKG1_ST	P43694	GATA4	Q13976	PRKG1	S262	R266H	266	Missense	distal	4	no	14.320	14.439	PhosphoSitePlus	ICGC;COSMIC	7.092	Up-regulation
AGC_PKG_PRKG1_ST	P43694	GATA4	Q13976	PRKG1	S262	R266S	266	Missense	distal	4	no	14.320	14.356	PhosphoSitePlus	ICGC;COSMIC	7.092	Up-regulation
AGC_PKG_PRKG1_ST	P61586	RHOA	Q13976	PRKG1	S26	I23R	23	Missense	distal	-3	no	0.827	9.334	EPSD	ICGC;COSMIC	7.092	Gain
AGC_PKG_PRKG1_ST	P61586	RHOA	Q13976	PRKG1	S73	P75R	75	Missense	proximal	2	no	7.618	7.705	EPSD	ICGC;COSMIC	7.092	Up-regulation
AGC_PKG_PRKG1_ST	P61586	RHOA	Q13976	PRKG1	S73	Y74D	74	Missense	proximal	1	no	7.618	7.586	EPSD	ICGC;COSMIC	7.092	Down-regulation
AGC_PKG_PRKG1_ST	P61586	RHOA	Q13976	PRKG1	S73	D76G	76	Missense	distal	3	no	7.618	7.576	EPSD	ICGC;COSMIC	7.092	Down-regulation
AGC_PKG_PRKG1_ST	P61586	RHOA	Q13976	PRKG1	S73	L69R	69	Missense	distal	-4	no	7.618	8.861	EPSD	ICGC;COSMIC	7.092	Up-regulation
AGC_PKG_PRKG1_ST	P61586	RHOA	Q13976	PRKG1	S73	D76V	76	Missense	distal	3	no	7.618	7.640	EPSD	ICGC;COSMIC	7.092	Up-regulation
AGC_PKG_PRKG1_ST	P61586	RHOA	Q13976	PRKG1	S73	D76N	76	Missense	distal	3	no	7.618	7.529	EPSD	ICGC;COSMIC	7.092	Down-regulation
AGC_PKG_PRKG1_ST	P10644	PRKAR1A	Q13976	PRKG1	S101	R96L	96	Missense	distal	-5	no	8.702	9.079	PhosphoSitePlus	ICGC	7.092	Up-regulation
AGC_PKG_PRKG1_ST	P10644	PRKAR1A	Q13976	PRKG1	S307	R306L	306	Missense	proximal	-1	no	9.166	8.864	EPSD	ICGC	7.092	Down-regulation
AGC_PKG_PRKG1_ST	P10644	PRKAR1A	Q13976	PRKG1	S307	A300T	300	Missense	distal	-7	no	9.166	9.112	EPSD	ICGC;COSMIC	7.092	Down-regulation
AGC_PKG_PRKG1_ST	P10644	PRKAR1A	Q13976	PRKG1	T338	M331I	331	Missense	distal	-7	no	7.694	6.572	EPSD	ICGC;COSMIC	7.092	Loss
AGC_PKG_PRKG1_ST	P10644	PRKAR1A	Q13976	PRKG1	T338	G343D	343	Missense	distal	5	no	7.694	7.679	EPSD	ICGC;COSMIC	7.092	Down-regulation
AGC_PKG_PRKG1_ST	P10644	PRKAR1A	Q13976	PRKG1	T338	R335H	335	Missense	distal	-3	no	7.694	1.626	EPSD	ICGC	7.092	Loss
AGC_PKG_PRKG1_ST	P10644	PRKAR1A	Q13976	PRKG1	T338	V340F	340	Missense	proximal	2	no	7.694	7.726	EPSD	ICGC	7.092	Up-regulation
AGC_PKG_PRKG1_ST	P11831	SRF	Q13976	PRKG1	S16	G19W	19	Missense	distal	3	no	9.131	9.221	EPSD	ICGC	7.092	Up-regulation
AGC_PKG_PRKG1_ST	P11831	SRF	Q13976	PRKG1	S16	G15V	15	Missense	proximal	-1	no	9.131	9.080	EPSD	ICGC;COSMIC	7.092	Down-regulation
AGC_PKG_PRKG1_ST	P11831	SRF	Q13976	PRKG1	S103	G108C	108	Missense	distal	5	no	11.758	11.765	EPSD	ICGC	7.092	Up-regulation
AGC_PKG_PRKG1_ST	P11831	SRF	Q13976	PRKG1	S103	G97A	97	Missense	distal	-6	no	11.758	11.932	EPSD	ICGC	7.092	Up-regulation
AGC_PKG_PRKG1_ST	P11831	SRF	Q13976	PRKG1	S103	E104D	104	Missense	proximal	1	no	11.758	11.684	EPSD	ICGC;COSMIC	7.092	Down-regulation
AGC_PKG_PRKG1_ST	P11831	SRF	Q13976	PRKG1	S237	A238S	238	Missense	proximal	1	no	10.171	10.184	EPSD	ICGC	7.092	Up-regulation
AGC_PKG_PRKG1_ST	P21731	TBXA2R	Q13976	PRKG1	S239	M244T	244	Missense	distal	5	no	9.523	9.524	EPSD	ICGC;COSMIC	7.092	Up-regulation
AGC_PKG_PRKG1_ST	P21731	TBXA2R	Q13976	PRKG1	S239	S239Y	239	Missense	central	0	yes	9.523	0.000	EPSD	ICGC	7.092	Loss
AGC_PKG_PRKG1_ST	P21731	TBXA2R	Q13976	PRKG1	S239	R237G	237	Missense	proximal	-2	no	9.523	6.035	EPSD	ICGC;COSMIC	7.092	Loss
AGC_PKG_PRKG1_ST	P21731	TBXA2R	Q13976	PRKG1	S239	R235H	235	Missense	distal	-4	no	9.523	8.767	EPSD	ICGC;COSMIC	7.092	Down-regulation
AGC_PKG_PRKG1_ST	P21731	TBXA2R	Q13976	PRKG1	S239	E242K	242	Missense	distal	3	no	9.523	9.349	EPSD	ICGC;COSMIC	7.092	Down-regulation
AGC_PKG_PRKG1_ST	P21731	TBXA2R	Q13976	PRKG1	S324	L319H	319	Missense	distal	-5	no	11.181	11.007	EPSD	ICGC;COSMIC	7.092	Down-regulation
AGC_PKG_PRKG1_ST	P21731	TBXA2R	Q13976	PRKG1	S324	S331F	331	Missense	distal	7	no	11.181	11.106	EPSD	ICGC	7.092	Down-regulation
AGC_PKG_PRKG1_ST	P21731	TBXA2R	Q13976	PRKG1	S324	P327S	327	Missense	distal	3	no	11.181	10.931	EPSD	ICGC	7.092	Down-regulation
AGC_PKG_PRKG1_ST	P21731	TBXA2R	Q13976	PRKG1	S329	Q333K	333	Missense	distal	4	no	11.239	11.220	EPSD	ICGC	7.092	Down-regulation
AGC_PKG_PRKG1_ST	P21731	TBXA2R	Q13976	PRKG1	S329	S331F	331	Missense	proximal	2	no	11.239	11.162	EPSD	ICGC	7.092	Down-regulation
AGC_PKG_PRKG1_ST	P21731	TBXA2R	Q13976	PRKG1	S329	P327S	327	Missense	proximal	-2	no	11.239	11.590	EPSD	ICGC	7.092	Up-regulation
AGC_PKG_PRKG1_ST	P21731	TBXA2R	Q13976	PRKG1	S329	L332F	332	Missense	distal	3	no	11.239	11.053	EPSD	ICGC;COSMIC	7.092	Down-regulation
AGC_PKG_PRKG1_ST	P21731	TBXA2R	Q13976	PRKG1	S331	T337M	337	Missense	distal	6	no	9.685	9.698	EPSD;PhosphoSitePlus	ICGC;COSMIC	7.092	Up-regulation
AGC_PKG_PRKG1_ST	P21731	TBXA2R	Q13976	PRKG1	S331	Q333K	333	Missense	proximal	2	no	9.685	9.677	EPSD;PhosphoSitePlus	ICGC	7.092	Down-regulation
AGC_PKG_PRKG1_ST	P21731	TBXA2R	Q13976	PRKG1	S331	S331F	331	Missense	central	0	yes	9.685	0.000	EPSD;PhosphoSitePlus	ICGC	7.092	Loss
AGC_PKG_PRKG1_ST	P21731	TBXA2R	Q13976	PRKG1	S331	P327S	327	Missense	distal	-4	no	9.685	10.108	EPSD;PhosphoSitePlus	ICGC	7.092	Up-regulation
AGC_PKG_PRKG1_ST	P21731	TBXA2R	Q13976	PRKG1	S331	L332F	332	Missense	proximal	1	no	9.685	9.938	EPSD;PhosphoSitePlus	ICGC;COSMIC	7.092	Up-regulation
AGC_PKG_PRKG1_ST	P35520	CBS	Q13976	PRKG1	S61	E62K	62	Missense	proximal	1	no	10.262	10.569	EPSD	ICGC	7.092	Up-regulation
AGC_PKG_PRKG1_ST	Q9Y210	TRPC6	Q13976	PRKG1	S13	A18V	18	Missense	distal	5	no	13.571	13.521	EPSD	ICGC;COSMIC	7.092	Down-regulation
AGC_PKG_PRKG1_ST	Q9Y210	TRPC6	Q13976	PRKG1	S13	P15S	15	Missense	proximal	2	no	13.571	13.669	EPSD	ICGC;COSMIC	7.092	Up-regulation
AGC_PKG_PRKG1_ST	Q9Y210	TRPC6	Q13976	PRKG1	S13	R16W	16	Missense	distal	3	no	13.571	13.888	EPSD	ICGC;COSMIC	7.092	Up-regulation
AGC_PKG_PRKG1_ST	Q9Y210	TRPC6	Q13976	PRKG1	S13	G20R	20	Missense	distal	7	no	13.571	13.684	EPSD	ICGC;COSMIC	7.092	Up-regulation
AGC_PKG_PRKG1_ST	Q9Y210	TRPC6	Q13976	PRKG1	S14	A18V	18	Missense	distal	4	no	12.504	12.643	EPSD	ICGC;COSMIC	7.092	Up-regulation
AGC_PKG_PRKG1_ST	Q9Y210	TRPC6	Q13976	PRKG1	S14	P15S	15	Missense	proximal	1	no	12.504	12.766	EPSD	ICGC;COSMIC	7.092	Up-regulation
AGC_PKG_PRKG1_ST	Q9Y210	TRPC6	Q13976	PRKG1	S14	R16W	16	Missense	proximal	2	no	12.504	12.403	EPSD	ICGC;COSMIC	7.092	Down-regulation
AGC_PKG_PRKG1_ST	Q9Y210	TRPC6	Q13976	PRKG1	S14	G20R	20	Missense	distal	6	no	12.504	12.288	EPSD	ICGC;COSMIC	7.092	Down-regulation
AGC_PKG_PRKG1_ST	Q9Y210	TRPC6	Q13976	PRKG1	S28	D35E	35	Missense	distal	7	no	8.754	8.768	EPSD	ICGC;COSMIC	7.092	Up-regulation
AGC_PKG_PRKG1_ST	Q9Y210	TRPC6	Q13976	PRKG1	S28	R24W	24	Missense	distal	-4	no	8.754	7.582	EPSD	ICGC;COSMIC	7.092	Down-regulation
AGC_PKG_PRKG1_ST	Q9Y210	TRPC6	Q13976	PRKG1	T70	G76E	76	Missense	distal	6	no	12.250	12.313	PhosphoSitePlus;EPSD	ICGC	7.092	Up-regulation
AGC_PKG_PRKG1_ST	Q9Y210	TRPC6	Q13976	PRKG1	T70	A65T	65	Missense	distal	-5	no	12.250	12.260	PhosphoSitePlus;EPSD	ICGC;COSMIC	7.092	Up-regulation
AGC_PKG_PRKG1_ST	Q9Y210	TRPC6	Q13976	PRKG1	S94	S96C	96	Missense	proximal	2	no	9.035	8.955	EPSD	ICGC	7.092	Down-regulation
AGC_PKG_PRKG1_ST	Q9Y210	TRPC6	Q13976	PRKG1	S94	S94N	94	Missense	central	0	yes	9.035	0.000	EPSD	ICGC;COSMIC	7.092	Loss
AGC_PKG_PRKG1_ST	Q9Y210	TRPC6	Q13976	PRKG1	S199	S197R	197	Missense	proximal	-2	no	5.087	8.495	EPSD	ICGC;COSMIC	7.092	Gain
AGC_PKG_PRKG1_ST	Q9Y210	TRPC6	Q13976	PRKG1	S322	S322L	322	Missense	central	0	yes	9.394	0.000	EPSD;PhosphoSitePlus	ICGC;COSMIC	7.092	Loss
AGC_PKG_PRKG1_ST	Q9Y210	TRPC6	Q13976	PRKG1	S836	D842N	842	Missense	distal	6	no	8.089	7.999	EPSD	ICGC;COSMIC	7.092	Down-regulation
AGC_PKG_PRKG1_ST	P35367	HRH1	Q13976	PRKG1	T142	S145L	145	Missense	distal	3	no	7.063	7.432	EPSD	ICGC;COSMIC;GDSC;CCLE	7.092	Gain
AGC_PKG_PRKG1_ST	P35367	HRH1	Q13976	PRKG1	S255	E258K	258	Missense	distal	3	no	7.729	7.555	EPSD	ICGC	7.092	Down-regulation
AGC_PKG_PRKG1_ST	P35367	HRH1	Q13976	PRKG1	S255	G252W	252	Missense	distal	-3	no	7.729	4.647	EPSD	ICGC;COSMIC	7.092	Loss
AGC_PKG_PRKG1_ST	P35367	HRH1	Q13976	PRKG1	S277	Q278K	278	Missense	proximal	1	no	8.189	8.224	EPSD	ICGC	7.092	Up-regulation
AGC_PKG_PRKG1_ST	P35367	HRH1	Q13976	PRKG1	S363	T365I	365	Missense	proximal	2	no	10.249	10.154	EPSD	ICGC;COSMIC	7.092	Down-regulation
AGC_PKG_PRKG1_ST	P35367	HRH1	Q13976	PRKG1	S363	A370T	370	Missense	distal	7	no	10.249	10.259	EPSD	ICGC;GDSC;CCLE	7.092	Up-regulation
AGC_PKG_PRKG1_ST	P35367	HRH1	Q13976	PRKG1	S396	S396W	396	Missense	central	0	yes	8.063	0.000	EPSD;PhosphoSitePlus	ICGC;COSMIC	7.092	Loss
AGC_PKG_PRKG1_ST	P35367	HRH1	Q13976	PRKG1	S396	R393S	393	Missense	distal	-3	no	8.063	2.575	EPSD;PhosphoSitePlus	ICGC;COSMIC	7.092	Loss
AGC_PKG_PRKG1_ST	P35367	HRH1	Q13976	PRKG1	S398	S396W	396	Missense	proximal	-2	no	9.845	7.922	PhosphoSitePlus;EPSD	ICGC;COSMIC	7.092	Down-regulation
AGC_PKG_PRKG1_ST	P35367	HRH1	Q13976	PRKG1	S398	R393S	393	Missense	distal	-5	no	9.845	9.985	PhosphoSitePlus;EPSD	ICGC;COSMIC	7.092	Up-regulation
AGC_PKG_PRKG1_ST	Q9NS28	RGS18	Q13976	PRKG1	S49	Q53L	53	Missense	distal	4	no	6.890	7.117	EPSD	ICGC;COSMIC	7.092	Gain
AGC_PKG_PRKG1_ST	Q9NS28	RGS18	Q13976	PRKG1	S64	R62S	62	Missense	proximal	-2	no	8.410	5.002	EPSD	ICGC;COSMIC	7.092	Loss
AGC_PKG_PRKG1_ST	Q9NS28	RGS18	Q13976	PRKG1	S76	T73P	73	Missense	distal	-3	no	6.984	7.247	EPSD	ICGC;COSMIC	7.092	Gain
AGC_PKG_PRKG1_ST	Q9NS28	RGS18	Q13976	PRKG1	S216	R217H	217	Missense	proximal	1	no	13.647	13.311	PhosphoSitePlus	ICGC;COSMIC	7.092	Down-regulation
AGC_PKG_PRKG1_ST	Q9NS28	RGS18	Q13976	PRKG1	S216	T220I	220	Missense	distal	4	no	13.647	13.844	PhosphoSitePlus	ICGC	7.092	Up-regulation
AGC_PKG_PRKG1_ST	Q9NS28	RGS18	Q13976	PRKG1	S218	R217H	217	Missense	proximal	-1	no	12.201	12.053	EPSD	ICGC;COSMIC	7.092	Down-regulation
AGC_PKG_PRKG1_ST	Q9NS28	RGS18	Q13976	PRKG1	S218	T220I	220	Missense	proximal	2	no	12.201	12.106	EPSD	ICGC	7.092	Down-regulation
AGC_PKG_PRKG1_ST	Q9NS28	RGS18	Q13976	PRKG1	T220	R217H	217	Missense	distal	-3	no	8.743	2.676	EPSD	ICGC;COSMIC	7.092	Loss
AGC_PKG_PRKG1_ST	Q9NS28	RGS18	Q13976	PRKG1	T220	T220I	220	Missense	central	0	yes	8.743	0.000	EPSD	ICGC	7.092	Loss
AGC_PKG_PRKG1_ST	Q9Y613	FHOD1	Q13976	PRKG1	S367	P374H	374	Missense	distal	7	no	8.047	8.104	EPSD	ICGC;COSMIC	7.092	Up-regulation
AGC_PKG_PRKG1_ST	Q9Y613	FHOD1	Q13976	PRKG1	T465	T465K	465	Missense	central	0	yes	7.320	0.000	EPSD	ICGC	7.092	Loss
AGC_PKG_PRKG1_ST	Q9Y613	FHOD1	Q13976	PRKG1	T465	A463T	463	Missense	proximal	-2	no	7.320	7.184	EPSD	ICGC;COSMIC	7.092	Down-regulation
AGC_PKG_PRKG1_ST	Q9Y613	FHOD1	Q13976	PRKG1	T465	A469S	469	Missense	distal	4	no	7.320	7.300	EPSD	ICGC;COSMIC	7.092	Down-regulation
AGC_PKG_PRKG1_ST	Q9Y613	FHOD1	Q13976	PRKG1	T690	K683E	683	Missense	distal	-7	no	7.418	6.417	EPSD	ICGC;COSMIC	7.092	Loss
AGC_PKG_PRKG1_ST	Q9Y613	FHOD1	Q13976	PRKG1	T690	P697T	697	Missense	distal	7	no	7.418	7.509	EPSD	ICGC	7.092	Up-regulation
AGC_PKG_PRKG1_ST	Q9Y613	FHOD1	Q13976	PRKG1	T690	T690K	690	Missense	central	0	yes	7.418	0.000	EPSD	ICGC	7.092	Loss
AGC_PKG_PRKG1_ST	Q9Y613	FHOD1	Q13976	PRKG1	T692	P697T	697	Missense	distal	5	no	8.640	8.707	EPSD	ICGC	7.092	Up-regulation
AGC_PKG_PRKG1_ST	Q9Y613	FHOD1	Q13976	PRKG1	T692	T690K	690	Missense	proximal	-2	no	8.640	10.755	EPSD	ICGC	7.092	Up-regulation
AGC_PKG_PRKG1_ST	Q9Y613	FHOD1	Q13976	PRKG1	T693	T690K	690	Missense	distal	-3	no	4.320	7.128	EPSD	ICGC	7.092	Gain
AGC_PKG_PRKG1_ST	Q9Y613	FHOD1	Q13976	PRKG1	S874	S875Y	875	Missense	proximal	1	no	8.367	8.065	EPSD	ICGC;COSMIC	7.092	Down-regulation
AGC_PKG_PRKG1_ST	Q9Y613	FHOD1	Q13976	PRKG1	S874	P872S	872	Missense	proximal	-2	no	8.367	8.718	EPSD	ICGC	7.092	Up-regulation
AGC_PKG_PRKG1_ST	Q9Y613	FHOD1	Q13976	PRKG1	T1016	R1011Q	1011	Missense	distal	-5	no	8.271	8.392	EPSD	ICGC;COSMIC	7.092	Up-regulation
AGC_PKG_PRKG1_ST	Q9Y613	FHOD1	Q13976	PRKG1	T1016	R1011L	1011	Missense	distal	-5	no	8.271	8.647	EPSD	ICGC;COSMIC	7.092	Up-regulation
AGC_PKG_PRKG1_ST	Q9Y613	FHOD1	Q13976	PRKG1	T1016	F1021L	1021	Missense	distal	5	no	8.271	8.202	EPSD	ICGC;COSMIC	7.092	Down-regulation
AGC_PKG_PRKG1_ST	Q9Y613	FHOD1	Q13976	PRKG1	S1131	R1135H	1135	Missense	distal	4	no	11.398	11.517	PhosphoSitePlus	ICGC;COSMIC	7.092	Up-regulation
AGC_PKG_PRKG1_ST	Q9Y613	FHOD1	Q13976	PRKG1	S1131	R1130C	1130	Missense	proximal	-1	no	11.398	11.196	PhosphoSitePlus	ICGC	7.092	Down-regulation
AGC_PKG_PRKG1_ST	Q9Y613	FHOD1	Q13976	PRKG1	S1131	R1130H	1130	Missense	proximal	-1	no	11.398	11.250	PhosphoSitePlus	ICGC;COSMIC;CCLE	7.092	Down-regulation
AGC_PKG_PRKG1_ST	Q9Y613	FHOD1	Q13976	PRKG1	S1137	R1135H	1135	Missense	proximal	-2	no	8.446	4.188	EPSD	ICGC;COSMIC	7.092	Loss
AGC_PKG_PRKG1_ST	Q9Y613	FHOD1	Q13976	PRKG1	S1137	R1130C	1130	Missense	distal	-7	no	8.446	7.018	EPSD	ICGC	7.092	Loss
AGC_PKG_PRKG1_ST	Q9Y613	FHOD1	Q13976	PRKG1	S1137	R1130H	1130	Missense	distal	-7	no	8.446	7.272	EPSD	ICGC;COSMIC;CCLE	7.092	Down-regulation
AGC_PKG_PRKG1_ST	P78347	GTF2I	Q13976	PRKG1	S95	T96A	96	Missense	proximal	1	no	7.447	7.484	EPSD	ICGC;COSMIC	7.092	Up-regulation
AGC_PKG_PRKG1_ST	P78347	GTF2I	Q13976	PRKG1	S95	R101L	101	Missense	distal	6	no	7.447	7.883	EPSD	ICGC;COSMIC	7.092	Up-regulation
AGC_PKG_PRKG1_ST	P78347	GTF2I	Q13976	PRKG1	S95	N100S	100	Missense	distal	5	no	7.447	7.480	EPSD	ICGC;COSMIC	7.092	Up-regulation
AGC_PKG_PRKG1_ST	P78347	GTF2I	Q13976	PRKG1	S103	T96A	96	Missense	distal	-7	no	7.368	7.422	EPSD	ICGC;COSMIC	7.092	Up-regulation
AGC_PKG_PRKG1_ST	P78347	GTF2I	Q13976	PRKG1	S103	I109F	109	Missense	distal	6	no	7.368	7.228	EPSD	ICGC;COSMIC	7.092	Down-regulation
AGC_PKG_PRKG1_ST	P78347	GTF2I	Q13976	PRKG1	S103	R101L	101	Missense	proximal	-2	no	7.368	2.074	EPSD	ICGC;COSMIC	7.092	Loss
AGC_PKG_PRKG1_ST	P78347	GTF2I	Q13976	PRKG1	S103	N100S	100	Missense	distal	-3	no	7.368	8.784	EPSD	ICGC;COSMIC	7.092	Up-regulation
AGC_PKG_PRKG1_ST	P78347	GTF2I	Q13976	PRKG1	S146	S146L	146	Missense	central	0	yes	8.106	0.000	EPSD	ICGC;COSMIC	7.092	Loss
AGC_PKG_PRKG1_ST	P78347	GTF2I	Q13976	PRKG1	S146	K140E	140	Missense	distal	-6	no	8.106	7.626	EPSD	ICGC	7.092	Down-regulation
AGC_PKG_PRKG1_ST	P78347	GTF2I	Q13976	PRKG1	S412	R409C	409	Missense	distal	-3	no	13.979	6.957	EPSD;PhosphoSitePlus	ICGC;COSMIC	7.092	Loss
AGC_PKG_PRKG1_ST	Q96D31	ORAI1	Q13976	PRKG1	S30	S30I	30	Missense	central	0	yes	8.529	0.000	EPSD	ICGC	7.092	Loss
AGC_PKG_PRKG1_ST	Q96D31	ORAI1	Q13976	PRKG1	S30	G37W	37	Missense	distal	7	no	8.529	8.487	EPSD	ICGC	7.092	Down-regulation
AGC_PKG_PRKG1_ST	Q96D31	ORAI1	Q13976	PRKG1	S34	S30I	30	Missense	distal	-4	no	14.447	13.608	PhosphoSitePlus	ICGC	7.092	Down-regulation
AGC_PKG_PRKG1_ST	Q96D31	ORAI1	Q13976	PRKG1	S34	G37W	37	Missense	distal	3	no	14.447	14.537	PhosphoSitePlus	ICGC	7.092	Up-regulation
AGC_PKG_PRKG1_ST	Q14847	LASP1	Q13976	PRKG1	S146	M139I	139	Missense	distal	-7	no	12.899	11.777	PhosphoSitePlus	ICGC;COSMIC	7.092	Down-regulation
AGC_PKG_PRKG1_ST	Q96A00	PPP1R14A	Q13976	PRKG1	S12	R9C	9	Missense	distal	-3	no	10.619	3.597	EPSD	ICGC	7.092	Loss
AGC_PKG_PRKG1_ST	Q96A00	PPP1R14A	Q13976	PRKG1	S16	R21C	21	Missense	distal	5	no	7.869	7.799	EPSD	ICGC;COSMIC	7.092	Down-regulation
AGC_PKG_PRKG1_ST	Q96A00	PPP1R14A	Q13976	PRKG1	S16	R9C	9	Missense	distal	-7	no	7.869	6.441	EPSD	ICGC	7.092	Loss
AGC_PKG_PRKG1_ST	Q684P5	RAP1GAP2	Q13976	PRKG1	S7	G3D	3	Missense	distal	-4	no	11.498	11.070	PhosphoSitePlus	ICGC;COSMIC	7.092	Down-regulation
AGC_PKG_PRKG1_ST	Q684P5	RAP1GAP2	Q13976	PRKG1	S7	G12V	12	Missense	distal	5	no	11.498	11.488	PhosphoSitePlus	ICGC;COSMIC	7.092	Down-regulation
AGC_PKG_PRKG1_ST	Q684P5	RAP1GAP2	Q13976	PRKG1	S7	R4W	4	Missense	distal	-3	no	11.498	3.826	PhosphoSitePlus	ICGC;COSMIC	7.092	Loss
AGC_PKG_PRKG1_ST	Q684P5	RAP1GAP2	Q13976	PRKG1	S9	G3D	3	Missense	distal	-6	no	10.185	9.910	EPSD	ICGC;COSMIC	7.092	Down-regulation
AGC_PKG_PRKG1_ST	Q684P5	RAP1GAP2	Q13976	PRKG1	S9	G12V	12	Missense	distal	3	no	10.185	10.249	EPSD	ICGC;COSMIC	7.092	Up-regulation
AGC_PKG_PRKG1_ST	Q684P5	RAP1GAP2	Q13976	PRKG1	S9	R4W	4	Missense	distal	-5	no	10.185	10.508	EPSD	ICGC;COSMIC	7.092	Up-regulation
AGC_PKG_PRKG1_ST	Q684P5	RAP1GAP2	Q13976	PRKG1	S45	P46H	46	Missense	proximal	1	no	10.367	10.468	EPSD	ICGC;COSMIC	7.092	Up-regulation
AGC_PKG_PRKG1_ST	Q684P5	RAP1GAP2	Q13976	PRKG1	S45	T49M	49	Missense	distal	4	no	10.367	10.385	EPSD	ICGC;COSMIC	7.092	Up-regulation
AGC_PKG_PRKG1_ST	Q684P5	RAP1GAP2	Q13976	PRKG1	S45	D41Y	41	Missense	distal	-4	no	10.367	10.569	EPSD	ICGC	7.092	Up-regulation
AGC_PKG_PRKG1_ST	Q684P5	RAP1GAP2	Q13976	PRKG1	S45	P47L	47	Missense	proximal	2	no	10.367	10.322	EPSD	ICGC;COSMIC	7.092	Down-regulation
AGC_PKG_PRKG1_ST	Q684P5	RAP1GAP2	Q13976	PRKG1	S45	P40Q	40	Missense	distal	-5	no	10.367	10.232	EPSD	ICGC;COSMIC	7.092	Down-regulation
AGC_PKG_PRKG1_ST	Q684P5	RAP1GAP2	Q13976	PRKG1	S57	E58D	58	Missense	proximal	1	no	8.283	8.209	EPSD	ICGC;COSMIC	7.092	Down-regulation
AGC_PKG_PRKG1_ST	Q684P5	RAP1GAP2	Q13976	PRKG1	S505	A500V	500	Missense	distal	-5	no	9.649	9.774	EPSD	ICGC;COSMIC	7.092	Up-regulation
AGC_PKG_PRKG1_ST	Q684P5	RAP1GAP2	Q13976	PRKG1	S505	E509K	509	Missense	distal	4	no	9.649	9.534	EPSD	ICGC;GDSC;CCLE	7.092	Down-regulation
AGC_PKG_PRKG1_ST	Q684P5	RAP1GAP2	Q13976	PRKG1	S505	V503I	503	Missense	proximal	-2	no	9.649	7.602	EPSD	ICGC;COSMIC;CCLE	7.092	Down-regulation
AGC_PKG_PRKG1_ST	Q684P5	RAP1GAP2	Q13976	PRKG1	S507	A500V	500	Missense	distal	-7	no	9.266	8.564	EPSD	ICGC;COSMIC	7.092	Down-regulation
AGC_PKG_PRKG1_ST	Q684P5	RAP1GAP2	Q13976	PRKG1	S507	E509K	509	Missense	proximal	2	no	9.266	9.317	EPSD	ICGC;GDSC;CCLE	7.092	Up-regulation
AGC_PKG_PRKG1_ST	Q684P5	RAP1GAP2	Q13976	PRKG1	S507	V503I	503	Missense	distal	-4	no	9.266	8.957	EPSD	ICGC;COSMIC;CCLE	7.092	Down-regulation
AGC_PKG_PRKG1_ST	Q684P5	RAP1GAP2	Q13976	PRKG1	S556	R557W	557	Missense	proximal	1	no	7.102	6.531	EPSD	ICGC;COSMIC	7.092	Loss
AGC_PKG_PRKG1_ST	Q684P5	RAP1GAP2	Q13976	PRKG1	S556	R563C	563	Missense	distal	7	no	7.102	6.990	EPSD	ICGC;COSMIC	7.092	Loss
AGC_PKG_PRKG1_ST	Q684P5	RAP1GAP2	Q13976	PRKG1	S556	K553N	553	Missense	distal	-3	no	7.102	2.555	EPSD	ICGC	7.092	Loss
AGC_PKG_PRKG1_ST	Q684P5	RAP1GAP2	Q13976	PRKG1	S556	A549V	549	Missense	distal	-7	no	7.102	6.399	EPSD	ICGC	7.092	Loss
AGC_PKG_PRKG1_ST	Q684P5	RAP1GAP2	Q13976	PRKG1	S556	A550T	550	Missense	distal	-6	no	7.102	7.062	EPSD	ICGC	7.092	Loss
AGC_PKG_PRKG1_ST	Q684P5	RAP1GAP2	Q13976	PRKG1	S564	R557W	557	Missense	distal	-7	no	13.411	11.646	EPSD	ICGC;COSMIC	7.092	Down-regulation
AGC_PKG_PRKG1_ST	Q684P5	RAP1GAP2	Q13976	PRKG1	S564	R563C	563	Missense	proximal	-1	no	13.411	13.209	EPSD	ICGC;COSMIC	7.092	Down-regulation
AGC_PKG_PRKG1_ST	Q684P5	RAP1GAP2	Q13976	PRKG1	S564	G565W	565	Missense	proximal	1	no	13.411	13.205	EPSD	ICGC;COSMIC	7.092	Down-regulation
AGC_PKG_PRKG1_ST	Q684P5	RAP1GAP2	Q13976	PRKG1	S564	P568H	568	Missense	distal	4	no	13.411	13.342	EPSD	ICGC;COSMIC	7.092	Down-regulation
AGC_PKG_PRKG1_ST	Q684P5	RAP1GAP2	Q13976	PRKG1	S586	R583Q	583	Missense	distal	-3	no	7.714	3.879	EPSD	ICGC;COSMIC	7.092	Loss
AGC_PKG_PRKG1_ST	Q684P5	RAP1GAP2	Q13976	PRKG1	S586	D579N	579	Missense	distal	-7	no	7.714	8.169	EPSD	ICGC	7.092	Up-regulation
AGC_PKG_PRKG1_ST	Q684P5	RAP1GAP2	Q13976	PRKG1	S586	A582T	582	Missense	distal	-4	no	7.714	7.599	EPSD	ICGC	7.092	Down-regulation
AGC_PKG_PRKG1_ST	Q684P5	RAP1GAP2	Q13976	PRKG1	T702	R699Q	699	Missense	distal	-3	no	7.846	4.011	EPSD	ICGC	7.092	Loss
AGC_PKG_PRKG1_ST	Q684P5	RAP1GAP2	Q13976	PRKG1	T702	S700G	700	Missense	proximal	-2	no	7.846	7.767	EPSD	ICGC	7.092	Down-regulation
AGC_PKG_PRKG1_ST	Q8WZ42	TTN	Q13976	PRKG1	S79	K81T	81	Missense	proximal	2	no	10.417	10.412	EPSD	ICGC;COSMIC	7.092	Down-regulation
AGC_PKG_PRKG1_ST	Q8WZ42	TTN	Q13976	PRKG1	S79	S86F	86	Missense	distal	7	no	10.417	10.342	EPSD	ICGC	7.092	Down-regulation
AGC_PKG_PRKG1_ST	Q8WZ42	TTN	Q13976	PRKG1	S79	G85R	85	Missense	distal	6	no	10.417	10.202	EPSD	ICGC	7.092	Down-regulation
AGC_PKG_PRKG1_ST	Q8WZ42	TTN	Q13976	PRKG1	S79	A73D	73	Missense	distal	-6	no	10.417	9.969	EPSD	ICGC;COSMIC	7.092	Down-regulation
AGC_PKG_PRKG1_ST	Q8WZ42	TTN	Q13976	PRKG1	S112	R109L	109	Missense	distal	-3	no	9.072	1.928	EPSD	ICGC;COSMIC	7.092	Loss
AGC_PKG_PRKG1_ST	Q8WZ42	TTN	Q13976	PRKG1	S112	V115M	115	Missense	distal	3	no	9.072	8.882	EPSD	ICGC;COSMIC;GDSC;CCLE	7.092	Down-regulation
AGC_PKG_PRKG1_ST	Q8WZ42	TTN	Q13976	PRKG1	S209	T206K	206	Missense	distal	-3	no	5.568	8.376	EPSD	ICGC	7.092	Gain
AGC_PKG_PRKG1_ST	Q8WZ42	TTN	Q13976	PRKG1	S263	P266Q	266	Missense	distal	3	no	8.914	8.670	EPSD	ICGC	7.092	Down-regulation
AGC_PKG_PRKG1_ST	Q8WZ42	TTN	Q13976	PRKG1	S263	R264G	264	Missense	proximal	1	no	8.914	8.550	EPSD	ICGC	7.092	Down-regulation
AGC_PKG_PRKG1_ST	Q8WZ42	TTN	Q13976	PRKG1	S265	P266Q	266	Missense	proximal	1	no	8.050	8.323	EPSD	ICGC	7.092	Up-regulation
AGC_PKG_PRKG1_ST	Q8WZ42	TTN	Q13976	PRKG1	S265	R264G	264	Missense	proximal	-1	no	8.050	7.885	EPSD	ICGC	7.092	Down-regulation
AGC_PKG_PRKG1_ST	Q8WZ42	TTN	Q13976	PRKG1	S265	I271T	271	Missense	distal	6	no	8.050	7.758	EPSD	ICGC	7.092	Down-regulation
AGC_PKG_PRKG1_ST	Q8WZ42	TTN	Q13976	PRKG1	T267	P266Q	266	Missense	proximal	-1	no	9.069	9.209	EPSD	ICGC	7.092	Up-regulation
AGC_PKG_PRKG1_ST	Q8WZ42	TTN	Q13976	PRKG1	T267	R264G	264	Missense	distal	-3	no	9.069	4.479	EPSD	ICGC	7.092	Loss
AGC_PKG_PRKG1_ST	Q8WZ42	TTN	Q13976	PRKG1	T267	I271T	271	Missense	distal	4	no	9.069	8.871	EPSD	ICGC	7.092	Down-regulation
AGC_PKG_PRKG1_ST	Q8WZ42	TTN	Q13976	PRKG1	S282	R279W	279	Missense	distal	-3	no	10.144	2.471	EPSD	ICGC;COSMIC;GDSC	7.092	Loss
AGC_PKG_PRKG1_ST	Q8WZ42	TTN	Q13976	PRKG1	S282	I286K	286	Missense	distal	4	no	10.144	9.928	EPSD	ICGC	7.092	Down-regulation
AGC_PKG_PRKG1_ST	Q8WZ42	TTN	Q13976	PRKG1	S289	I286K	286	Missense	distal	-3	no	4.952	11.100	EPSD	ICGC	7.092	Gain
AGC_PKG_PRKG1_ST	Q8WZ42	TTN	Q13976	PRKG1	T300	A298E	298	Missense	proximal	-2	no	8.818	7.273	EPSD	ICGC	7.092	Down-regulation
AGC_PKG_PRKG1_ST	Q8WZ42	TTN	Q13976	PRKG1	T300	H295Q	295	Missense	distal	-5	no	8.818	8.736	EPSD	ICGC;COSMIC	7.092	Down-regulation
AGC_PKG_PRKG1_ST	Q8WZ42	TTN	Q13976	PRKG1	T300	S306F	306	Missense	distal	6	no	8.818	9.009	EPSD	ICGC	7.092	Up-regulation
AGC_PKG_PRKG1_ST	Q8WZ42	TTN	Q13976	PRKG1	T300	P301S	301	Missense	proximal	1	no	8.818	9.080	EPSD	ICGC	7.092	Up-regulation
AGC_PKG_PRKG1_ST	Q8WZ42	TTN	Q13976	PRKG1	T300	S302Y	302	Missense	proximal	2	no	8.818	8.726	EPSD	ICGC;COSMIC	7.092	Down-regulation
AGC_PKG_PRKG1_ST	Q8WZ42	TTN	Q13976	PRKG1	S308	S306F	306	Missense	proximal	-2	no	9.833	9.071	EPSD	ICGC	7.092	Down-regulation
AGC_PKG_PRKG1_ST	Q8WZ42	TTN	Q13976	PRKG1	S308	P301S	301	Missense	distal	-7	no	9.833	10.600	EPSD	ICGC	7.092	Up-regulation
AGC_PKG_PRKG1_ST	Q8WZ42	TTN	Q13976	PRKG1	S308	S302Y	302	Missense	distal	-6	no	9.833	9.469	EPSD	ICGC;COSMIC	7.092	Down-regulation
AGC_PKG_PRKG1_ST	Q8WZ42	TTN	Q13976	PRKG1	S314	S320Y	320	Missense	distal	6	no	8.828	9.022	EPSD	ICGC;COSMIC	7.092	Up-regulation
AGC_PKG_PRKG1_ST	Q8WZ42	TTN	Q13976	PRKG1	T330	R328C	328	Missense	proximal	-2	no	7.819	3.090	EPSD	ICGC;COSMIC	7.092	Loss
AGC_PKG_PRKG1_ST	Q8WZ42	TTN	Q13976	PRKG1	T330	T334I	334	Missense	distal	4	no	7.819	8.017	EPSD	ICGC	7.092	Up-regulation
AGC_PKG_PRKG1_ST	Q8WZ42	TTN	Q13976	PRKG1	S540	T544N	544	Missense	distal	4	no	8.164	8.222	EPSD	ICGC	7.092	Up-regulation
AGC_PKG_PRKG1_ST	Q8WZ42	TTN	Q13976	PRKG1	S540	S540Y	540	Missense	central	0	yes	8.164	0.000	EPSD	ICGC;COSMIC	7.092	Loss
AGC_PKG_PRKG1_ST	Q8WZ42	TTN	Q13976	PRKG1	S742	R740H	740	Missense	proximal	-2	no	7.300	3.042	EPSD	ICGC;COSMIC	7.092	Loss
AGC_PKG_PRKG1_ST	Q8WZ42	TTN	Q13976	PRKG1	S742	A744T	744	Missense	proximal	2	no	7.300	7.292	EPSD	ICGC;COSMIC	7.092	Down-regulation
AGC_PKG_PRKG1_ST	Q8WZ42	TTN	Q13976	PRKG1	S742	R740C	740	Missense	proximal	-2	no	7.300	2.571	EPSD	ICGC;COSMIC;CCLE	7.092	Loss
AGC_PKG_PRKG1_ST	Q8WZ42	TTN	Q13976	PRKG1	S742	R740S	740	Missense	proximal	-2	no	7.300	3.892	EPSD	ICGC;COSMIC	7.092	Loss
AGC_PKG_PRKG1_ST	Q8WZ42	TTN	Q13976	PRKG1	S742	G736E	736	Missense	distal	-6	no	7.300	7.169	EPSD	ICGC;COSMIC;CCLE	7.092	Down-regulation
AGC_PKG_PRKG1_ST	Q8WZ42	TTN	Q13976	PRKG1	S742	A744V	744	Missense	proximal	2	no	7.300	7.215	EPSD	ICGC;COSMIC	7.092	Down-regulation
AGC_PKG_PRKG1_ST	Q8WZ42	TTN	Q13976	PRKG1	S742	S742F	742	Missense	central	0	yes	7.300	0.000	EPSD	ICGC	7.092	Loss
AGC_PKG_PRKG1_ST	Q8WZ42	TTN	Q13976	PRKG1	S755	P750H	750	Missense	distal	-5	no	8.887	8.834	EPSD	ICGC;COSMIC	7.092	Down-regulation
AGC_PKG_PRKG1_ST	Q8WZ42	TTN	Q13976	PRKG1	S755	K762R	762	Missense	distal	7	no	8.887	8.930	EPSD	ICGC	7.092	Up-regulation
AGC_PKG_PRKG1_ST	Q8WZ42	TTN	Q13976	PRKG1	S755	P761S	761	Missense	distal	6	no	8.887	8.652	EPSD	ICGC	7.092	Down-regulation
AGC_PKG_PRKG1_ST	Q8WZ42	TTN	Q13976	PRKG1	T795	K792R	792	Missense	distal	-3	no	7.363	9.721	EPSD	ICGC;COSMIC;GDSC;CCLE	7.092	Up-regulation
AGC_PKG_PRKG1_ST	Q8WZ42	TTN	Q13976	PRKG1	T795	S788L	788	Missense	distal	-7	no	7.363	5.980	EPSD	ICGC;COSMIC	7.092	Loss
AGC_PKG_PRKG1_ST	Q8WZ42	TTN	Q13976	PRKG1	T811	T811I	811	Missense	central	0	yes	7.914	0.000	EPSD	ICGC;COSMIC	7.092	Loss
AGC_PKG_PRKG1_ST	Q8WZ42	TTN	Q13976	PRKG1	T811	R808H	808	Missense	distal	-3	no	7.914	1.846	EPSD	ICGC;COSMIC	7.092	Loss
AGC_PKG_PRKG1_ST	Q8WZ42	TTN	Q13976	PRKG1	T811	A812D	812	Missense	proximal	1	no	7.914	7.592	EPSD	ICGC	7.092	Down-regulation
AGC_PKG_PRKG1_ST	Q8WZ42	TTN	Q13976	PRKG1	T811	S813R	813	Missense	proximal	2	no	7.914	7.902	EPSD	ICGC	7.092	Down-regulation
AGC_PKG_PRKG1_ST	Q8WZ42	TTN	Q13976	PRKG1	T811	P809A	809	Missense	proximal	-2	no	7.914	8.217	EPSD	ICGC;COSMIC	7.092	Up-regulation
AGC_PKG_PRKG1_ST	Q8WZ42	TTN	Q13976	PRKG1	T811	H815Y	815	Missense	distal	4	no	7.914	7.981	EPSD	ICGC	7.092	Up-regulation
AGC_PKG_PRKG1_ST	Q8WZ42	TTN	Q13976	PRKG1	T811	H804Y	804	Missense	distal	-7	no	7.914	7.665	EPSD	ICGC	7.092	Down-regulation
AGC_PKG_PRKG1_ST	Q8WZ42	TTN	Q13976	PRKG1	T811	H815D	815	Missense	distal	4	no	7.914	7.965	EPSD	ICGC;COSMIC	7.092	Up-regulation
AGC_PKG_PRKG1_ST	Q8WZ42	TTN	Q13976	PRKG1	S813	T811I	811	Missense	proximal	-2	no	8.560	6.147	EPSD	ICGC;COSMIC	7.092	Loss
AGC_PKG_PRKG1_ST	Q8WZ42	TTN	Q13976	PRKG1	S813	R808H	808	Missense	distal	-5	no	8.560	8.762	EPSD	ICGC;COSMIC	7.092	Up-regulation
AGC_PKG_PRKG1_ST	Q8WZ42	TTN	Q13976	PRKG1	S813	A812D	812	Missense	proximal	-1	no	8.560	8.405	EPSD	ICGC	7.092	Down-regulation
AGC_PKG_PRKG1_ST	Q8WZ42	TTN	Q13976	PRKG1	S813	S813R	813	Missense	central	0	yes	8.560	0.000	EPSD	ICGC	7.092	Loss
AGC_PKG_PRKG1_ST	Q8WZ42	TTN	Q13976	PRKG1	S813	P809A	809	Missense	distal	-4	no	8.560	8.979	EPSD	ICGC;COSMIC	7.092	Up-regulation
AGC_PKG_PRKG1_ST	Q8WZ42	TTN	Q13976	PRKG1	S813	H815Y	815	Missense	proximal	2	no	8.560	8.522	EPSD	ICGC	7.092	Down-regulation
AGC_PKG_PRKG1_ST	Q8WZ42	TTN	Q13976	PRKG1	S813	H815D	815	Missense	proximal	2	no	8.560	8.527	EPSD	ICGC;COSMIC	7.092	Down-regulation
AGC_PKG_PRKG1_ST	Q8WZ42	TTN	Q13976	PRKG1	S851	T856S	856	Missense	distal	5	no	7.471	7.476	EPSD	ICGC;COSMIC	7.092	Up-regulation
AGC_PKG_PRKG1_ST	Q8WZ42	TTN	Q13976	PRKG1	S1348	V1353A	1353	Missense	distal	5	no	7.863	7.913	EPSD	ICGC	7.092	Up-regulation
AGC_PKG_PRKG1_ST	Q8WZ42	TTN	Q13976	PRKG1	S1411	I1415M	1415	Missense	distal	4	no	12.218	12.038	EPSD	ICGC	7.092	Down-regulation
AGC_PKG_PRKG1_ST	Q8WZ42	TTN	Q13976	PRKG1	S1418	I1415M	1415	Missense	distal	-3	no	4.213	7.416	EPSD	ICGC	7.092	Gain
AGC_PKG_PRKG1_ST	Q8WZ42	TTN	Q13976	PRKG1	S1423	P1424T	1424	Missense	proximal	1	no	9.899	10.110	EPSD	ICGC	7.092	Up-regulation
AGC_PKG_PRKG1_ST	Q8WZ42	TTN	Q13976	PRKG1	S1423	R1421Q	1421	Missense	proximal	-2	no	9.899	6.934	EPSD	ICGC	7.092	Loss
AGC_PKG_PRKG1_ST	Q8WZ42	TTN	Q13976	PRKG1	S1428	P1424T	1424	Missense	distal	-4	no	11.058	11.363	EPSD	ICGC	7.092	Up-regulation
AGC_PKG_PRKG1_ST	Q8WZ42	TTN	Q13976	PRKG1	S1428	R1421Q	1421	Missense	distal	-7	no	11.058	10.382	EPSD	ICGC	7.092	Down-regulation
AGC_PKG_PRKG1_ST	Q8WZ42	TTN	Q13976	PRKG1	S1428	S1433C	1433	Missense	distal	5	no	11.058	11.011	EPSD	ICGC;COSMIC	7.092	Down-regulation
AGC_PKG_PRKG1_ST	Q8WZ42	TTN	Q13976	PRKG1	S1433	S1433C	1433	Missense	central	0	yes	9.496	0.000	EPSD	ICGC;COSMIC	7.092	Loss
AGC_PKG_PRKG1_ST	Q8WZ42	TTN	Q13976	PRKG1	S1433	S1438P	1438	Missense	distal	5	no	9.496	9.424	EPSD	ICGC;COSMIC	7.092	Down-regulation
AGC_PKG_PRKG1_ST	Q8WZ42	TTN	Q13976	PRKG1	S1438	L1443P	1443	Missense	distal	5	no	9.145	9.189	EPSD	ICGC;COSMIC;GDSC	7.092	Up-regulation
AGC_PKG_PRKG1_ST	Q8WZ42	TTN	Q13976	PRKG1	S1438	R1442G	1442	Missense	distal	4	no	9.145	9.292	EPSD	ICGC;COSMIC	7.092	Up-regulation
AGC_PKG_PRKG1_ST	Q8WZ42	TTN	Q13976	PRKG1	S1438	R1441S	1441	Missense	distal	3	no	9.145	9.210	EPSD	ICGC	7.092	Up-regulation
AGC_PKG_PRKG1_ST	Q8WZ42	TTN	Q13976	PRKG1	S1438	S1433C	1433	Missense	distal	-5	no	9.145	9.261	EPSD	ICGC;COSMIC	7.092	Up-regulation
AGC_PKG_PRKG1_ST	Q8WZ42	TTN	Q13976	PRKG1	S1438	S1438P	1438	Missense	central	0	yes	9.145	0.000	EPSD	ICGC;COSMIC	7.092	Loss
AGC_PKG_PRKG1_ST	Q8WZ42	TTN	Q13976	PRKG1	T1710	P1703L	1703	Missense	distal	-7	no	8.254	7.638	EPSD	ICGC;COSMIC	7.092	Down-regulation
AGC_PKG_PRKG1_ST	Q8WZ42	TTN	Q13976	PRKG1	T1710	L1709P	1709	Missense	proximal	-1	no	8.254	8.352	EPSD	ICGC	7.092	Up-regulation
AGC_PKG_PRKG1_ST	Q8WZ42	TTN	Q13976	PRKG1	T1710	K1715T	1715	Missense	distal	5	no	8.254	8.245	EPSD	ICGC;COSMIC	7.092	Down-regulation
AGC_PKG_PRKG1_ST	Q8WZ42	TTN	Q13976	PRKG1	T1710	K1715N	1715	Missense	distal	5	no	8.254	8.217	EPSD	ICGC;COSMIC	7.092	Down-regulation
AGC_PKG_PRKG1_ST	Q8WZ42	TTN	Q13976	PRKG1	S2086	I2080N	2080	Missense	distal	-6	no	6.947	7.301	EPSD	ICGC;COSMIC	7.092	Gain
AGC_PKG_PRKG1_ST	Q8WZ42	TTN	Q13976	PRKG1	T2190	E2187K	2187	Missense	distal	-3	no	2.846	7.429	EPSD	ICGC;COSMIC;GDSC;CCLE	7.092	Gain
AGC_PKG_PRKG1_ST	Q8WZ42	TTN	Q13976	PRKG1	S2441	S2437N	2437	Missense	distal	-4	no	7.430	7.058	EPSD	ICGC;COSMIC	7.092	Loss
AGC_PKG_PRKG1_ST	Q8WZ42	TTN	Q13976	PRKG1	S2441	R2439C	2439	Missense	proximal	-2	no	7.430	2.702	EPSD	ICGC;COSMIC	7.092	Loss
AGC_PKG_PRKG1_ST	Q8WZ42	TTN	Q13976	PRKG1	S2441	Y2443H	2443	Missense	proximal	2	no	7.430	7.469	EPSD	ICGC;COSMIC	7.092	Up-regulation
AGC_PKG_PRKG1_ST	Q8WZ42	TTN	Q13976	PRKG1	S2441	L2434P	2434	Missense	distal	-7	no	7.430	8.046	EPSD	ICGC;COSMIC	7.092	Up-regulation
AGC_PKG_PRKG1_ST	Q8WZ42	TTN	Q13976	PRKG1	S2441	L2434F	2434	Missense	distal	-7	no	7.430	8.169	EPSD	ICGC	7.092	Up-regulation
AGC_PKG_PRKG1_ST	Q8WZ42	TTN	Q13976	PRKG1	T3022	T3022I	3022	Missense	central	0	yes	7.854	0.000	EPSD	ICGC;COSMIC	7.092	Loss
AGC_PKG_PRKG1_ST	Q8WZ42	TTN	Q13976	PRKG1	S3122	M3121L	3121	Missense	proximal	-1	no	7.720	7.530	EPSD	ICGC;COSMIC	7.092	Down-regulation
AGC_PKG_PRKG1_ST	Q8WZ42	TTN	Q13976	PRKG1	S3122	S3118F	3118	Missense	distal	-4	no	7.720	7.274	EPSD	ICGC;COSMIC	7.092	Down-regulation
AGC_PKG_PRKG1_ST	Q8WZ42	TTN	Q13976	PRKG1	S3213	T3219N	3219	Missense	distal	6	no	7.889	7.992	EPSD	ICGC;COSMIC	7.092	Up-regulation
AGC_PKG_PRKG1_ST	Q8WZ42	TTN	Q13976	PRKG1	S3213	Q3212K	3212	Missense	proximal	-1	no	7.889	7.895	EPSD	ICGC;COSMIC	7.092	Up-regulation
AGC_PKG_PRKG1_ST	Q8WZ42	TTN	Q13976	PRKG1	S3213	S3208P	3208	Missense	distal	-5	no	7.889	8.004	EPSD	ICGC	7.092	Up-regulation
AGC_PKG_PRKG1_ST	Q8WZ42	TTN	Q13976	PRKG1	S3213	F3206L	3206	Missense	distal	-7	no	7.889	7.151	EPSD	ICGC;COSMIC	7.092	Down-regulation
AGC_PKG_PRKG1_ST	Q8WZ42	TTN	Q13976	PRKG1	S3228	A3222E	3222	Missense	distal	-6	no	7.664	7.360	EPSD	ICGC	7.092	Down-regulation
AGC_PKG_PRKG1_ST	Q8WZ42	TTN	Q13976	PRKG1	S3369	T3371K	3371	Missense	proximal	2	no	9.084	9.089	EPSD	ICGC	7.092	Up-regulation
AGC_PKG_PRKG1_ST	Q8WZ42	TTN	Q13976	PRKG1	S3918	E3915K	3915	Missense	distal	-3	no	5.727	10.310	EPSD	ICGC;COSMIC	7.092	Gain
AGC_PKG_PRKG1_ST	Q8WZ42	TTN	Q13976	PRKG1	S4010	E4007K	4007	Missense	distal	-3	no	3.624	8.207	EPSD;PhosphoSitePlus	ICGC;COSMIC	7.092	Gain
AGC_PKG_PRKG1_ST	Q8WZ42	TTN	Q13976	PRKG1	S4065	E4072K	4072	Missense	distal	7	no	7.354	7.439	EPSD	ICGC;COSMIC	7.092	Up-regulation
AGC_PKG_PRKG1_ST	Q8WZ42	TTN	Q13976	PRKG1	S4065	D4059G	4059	Missense	distal	-6	no	7.354	7.629	EPSD	ICGC;COSMIC;CCLE	7.092	Up-regulation
AGC_PKG_PRKG1_ST	Q8WZ42	TTN	Q13976	PRKG1	S4065	E4064K	4064	Missense	proximal	-1	no	7.354	7.516	EPSD	ICGC;COSMIC	7.092	Up-regulation
AGC_PKG_PRKG1_ST	Q8WZ42	TTN	Q13976	PRKG1	S4065	K4063E	4063	Missense	proximal	-2	no	7.354	3.832	EPSD	ICGC;COSMIC	7.092	Loss
AGC_PKG_PRKG1_ST	Q8WZ42	TTN	Q13976	PRKG1	S4065	L4061F	4061	Missense	distal	-4	no	7.354	7.681	EPSD	ICGC	7.092	Up-regulation
AGC_PKG_PRKG1_ST	Q8WZ42	TTN	Q13976	PRKG1	S4065	P4071L	4071	Missense	distal	6	no	7.354	7.483	EPSD	ICGC;COSMIC	7.092	Up-regulation
AGC_PKG_PRKG1_ST	Q8WZ42	TTN	Q13976	PRKG1	S4065	D4059N	4059	Missense	distal	-6	no	7.354	7.565	EPSD	ICGC;COSMIC	7.092	Up-regulation
AGC_PKG_PRKG1_ST	Q8WZ42	TTN	Q13976	PRKG1	S4065	P4071S	4071	Missense	distal	6	no	7.354	7.119	EPSD	ICGC;COSMIC	7.092	Down-regulation
AGC_PKG_PRKG1_ST	Q8WZ42	TTN	Q13976	PRKG1	S4065	L4061I	4061	Missense	distal	-4	no	7.354	7.288	EPSD	ICGC	7.092	Down-regulation
AGC_PKG_PRKG1_ST	Q8WZ42	TTN	Q13976	PRKG1	S4185	E4188G	4188	Missense	distal	3	no	8.004	7.977	PhosphoSitePlus;EPSD	ICGC;COSMIC	7.092	Down-regulation
AGC_PKG_PRKG1_ST	Q8WZ42	TTN	Q13976	PRKG1	S4185	I4178F	4178	Missense	distal	-7	no	8.004	8.738	PhosphoSitePlus;EPSD	ICGC;COSMIC	7.092	Up-regulation
AGC_PKG_PRKG1_ST	Q8WZ42	TTN	Q13976	PRKG1	S4185	M4190I	4190	Missense	distal	5	no	8.004	7.910	PhosphoSitePlus;EPSD	ICGC;COSMIC	7.092	Down-regulation
AGC_PKG_PRKG1_ST	Q8WZ42	TTN	Q13976	PRKG1	S4185	T4184K	4184	Missense	proximal	-1	no	8.004	8.048	PhosphoSitePlus;EPSD	ICGC	7.092	Up-regulation
AGC_PKG_PRKG1_ST	Q8WZ42	TTN	Q13976	PRKG1	S4185	A4182D	4182	Missense	distal	-3	no	8.004	4.095	PhosphoSitePlus;EPSD	ICGC;COSMIC	7.092	Loss
AGC_PKG_PRKG1_ST	Q8WZ42	TTN	Q13976	PRKG1	S4185	E4188K	4188	Missense	distal	3	no	8.004	7.831	PhosphoSitePlus;EPSD	ICGC;COSMIC	7.092	Down-regulation
AGC_PKG_PRKG1_ST	Q8WZ42	TTN	Q13976	PRKG1	S4185	S4192F	4192	Missense	distal	7	no	8.004	7.929	PhosphoSitePlus;EPSD	ICGC;COSMIC	7.092	Down-regulation
AGC_PKG_PRKG1_ST	Q8WZ42	TTN	Q13976	PRKG1	S4185	D4191N	4191	Missense	distal	6	no	8.004	7.914	PhosphoSitePlus;EPSD	ICGC;COSMIC;CCLE	7.092	Down-regulation
AGC_PKG_PRKG1_ST	Q8WZ42	TTN	Q13976	PRKG1	S4185	A4182T	4182	Missense	distal	-3	no	8.004	7.417	PhosphoSitePlus;EPSD	ICGC	7.092	Down-regulation
AGC_PKG_PRKG1_ST	Q8WZ42	TTN	Q13976	PRKG1	S4185	Q4187P	4187	Missense	proximal	2	no	8.004	7.924	PhosphoSitePlus;EPSD	ICGC	7.092	Down-regulation
AGC_PKG_PRKG1_ST	Q8WZ42	TTN	Q13976	PRKG1	S4185	S4185R	4185	Missense	central	0	yes	8.004	0.000	PhosphoSitePlus;EPSD	ICGC;COSMIC	7.092	Loss
AGC_PKG_PRKG1_ST	Q8WZ42	TTN	Q13976	PRKG1	S4486	L4487I	4487	Missense	proximal	1	no	9.991	10.018	EPSD	ICGC	7.092	Up-regulation
AGC_PKG_PRKG1_ST	Q8WZ42	TTN	Q13976	PRKG1	S4486	K4485T	4485	Missense	proximal	-1	no	9.991	9.947	EPSD	ICGC;COSMIC	7.092	Down-regulation
AGC_PKG_PRKG1_ST	Q8WZ42	TTN	Q13976	PRKG1	S4486	T4489S	4489	Missense	distal	3	no	9.991	9.999	EPSD	ICGC;COSMIC	7.092	Up-regulation
AGC_PKG_PRKG1_ST	Q8WZ42	TTN	Q13976	PRKG1	S4486	T4488K	4488	Missense	proximal	2	no	9.991	9.996	EPSD	ICGC;COSMIC	7.092	Up-regulation
AGC_PKG_PRKG1_ST	Q8WZ42	TTN	Q13976	PRKG1	S4486	K4485N	4485	Missense	proximal	-1	no	9.991	9.864	EPSD	ICGC;COSMIC	7.092	Down-regulation
AGC_PKG_PRKG1_ST	Q8WZ42	TTN	Q13976	PRKG1	S4486	F4490V	4490	Missense	distal	4	no	9.991	10.022	EPSD	ICGC	7.092	Up-regulation
AGC_PKG_PRKG1_ST	Q8WZ42	TTN	Q13976	PRKG1	S4993	R4991Q	4991	Missense	proximal	-2	no	7.630	4.665	EPSD	ICGC;COSMIC	7.092	Loss
AGC_PKG_PRKG1_ST	Q8WZ42	TTN	Q13976	PRKG1	S4993	V4998I	4998	Missense	distal	5	no	7.630	7.594	EPSD	ICGC;COSMIC	7.092	Down-regulation
AGC_PKG_PRKG1_ST	Q8WZ42	TTN	Q13976	PRKG1	S4993	A4986T	4986	Missense	distal	-7	no	7.630	7.575	EPSD	ICGC;COSMIC	7.092	Down-regulation
AGC_PKG_PRKG1_ST	Q8WZ42	TTN	Q13976	PRKG1	S4993	N4996I	4996	Missense	distal	3	no	7.630	7.834	EPSD	ICGC;COSMIC	7.092	Up-regulation
AGC_PKG_PRKG1_ST	Q8WZ42	TTN	Q13976	PRKG1	S4993	S4993I	4993	Missense	central	0	yes	7.630	0.000	EPSD	ICGC;COSMIC	7.092	Loss
AGC_PKG_PRKG1_ST	Q8WZ42	TTN	Q13976	PRKG1	S4993	N4997S	4997	Missense	distal	4	no	7.630	7.548	EPSD	ICGC;COSMIC	7.092	Down-regulation
AGC_PKG_PRKG1_ST	Q8WZ42	TTN	Q13976	PRKG1	S4993	A4986D	4986	Missense	distal	-7	no	7.630	6.725	EPSD	ICGC;COSMIC	7.092	Loss
AGC_PKG_PRKG1_ST	Q8WZ42	TTN	Q13976	PRKG1	S4993	N4996S	4996	Missense	distal	3	no	7.630	7.514	EPSD	ICGC	7.092	Down-regulation
AGC_PKG_PRKG1_ST	Q8WZ42	TTN	Q13976	PRKG1	S4993	S4993A	4993	Missense	central	0	yes	7.630	0.000	EPSD	ICGC	7.092	Loss
AGC_PKG_PRKG1_ST	Q8WZ42	TTN	Q13976	PRKG1	S4993	S4993R	4993	Missense	central	0	yes	7.630	0.000	EPSD	ICGC	7.092	Loss
AGC_PKG_PRKG1_ST	Q8WZ42	TTN	Q13976	PRKG1	S5072	G5077C	5077	Missense	distal	5	no	9.375	9.381	EPSD	ICGC;COSMIC	7.092	Up-regulation
AGC_PKG_PRKG1_ST	Q8WZ42	TTN	Q13976	PRKG1	S5072	K5078I	5078	Missense	distal	6	no	9.375	9.718	EPSD	ICGC;COSMIC	7.092	Up-regulation
AGC_PKG_PRKG1_ST	Q8WZ42	TTN	Q13976	PRKG1	S5072	S5066F	5066	Missense	distal	-6	no	9.375	9.078	EPSD	ICGC	7.092	Down-regulation
AGC_PKG_PRKG1_ST	Q8WZ42	TTN	Q13976	PRKG1	S5072	W5073L	5073	Missense	proximal	1	no	9.375	9.278	EPSD	ICGC;COSMIC	7.092	Down-regulation
AGC_PKG_PRKG1_ST	Q8WZ42	TTN	Q13976	PRKG1	S5072	G5077D	5077	Missense	distal	5	no	9.375	9.360	EPSD	ICGC	7.092	Down-regulation
AGC_PKG_PRKG1_ST	Q8WZ42	TTN	Q13976	PRKG1	S5072	P5068S	5068	Missense	distal	-4	no	9.375	9.798	EPSD	ICGC;COSMIC	7.092	Up-regulation
AGC_PKG_PRKG1_ST	Q8WZ42	TTN	Q13976	PRKG1	S5072	E5079K	5079	Missense	distal	7	no	9.375	9.459	EPSD	ICGC;COSMIC	7.092	Up-regulation
AGC_PKG_PRKG1_ST	Q8WZ42	TTN	Q13976	PRKG1	S5072	G5065C	5065	Missense	distal	-7	no	9.375	9.096	EPSD	ICGC;COSMIC	7.092	Down-regulation
AGC_PKG_PRKG1_ST	Q8WZ42	TTN	Q13976	PRKG1	S5123	S5120R	5120	Missense	distal	-3	no	6.403	11.892	EPSD	ICGC	7.092	Gain
AGC_PKG_PRKG1_ST	Q8WZ42	TTN	Q13976	PRKG1	S5124	S5120R	5120	Missense	distal	-4	no	6.677	7.147	EPSD	ICGC	7.092	Gain
AGC_PKG_PRKG1_ST	Q8WZ42	TTN	Q13976	PRKG1	S5141	F5135S	5135	Missense	distal	-6	no	8.350	8.647	EPSD	ICGC;COSMIC	7.092	Up-regulation
AGC_PKG_PRKG1_ST	Q8WZ42	TTN	Q13976	PRKG1	S5141	G5147A	5147	Missense	distal	6	no	8.350	8.239	EPSD	ICGC;COSMIC	7.092	Down-regulation
AGC_PKG_PRKG1_ST	Q8WZ42	TTN	Q13976	PRKG1	S5141	V5144I	5144	Missense	distal	3	no	8.350	8.444	EPSD	ICGC;COSMIC	7.092	Up-regulation
AGC_PKG_PRKG1_ST	Q8WZ42	TTN	Q13976	PRKG1	S5141	P5139H	5139	Missense	proximal	-2	no	8.350	7.852	EPSD	ICGC	7.092	Down-regulation
AGC_PKG_PRKG1_ST	Q8WZ42	TTN	Q13976	PRKG1	S5141	P5139S	5139	Missense	proximal	-2	no	8.350	8.701	EPSD	ICGC;COSMIC	7.092	Up-regulation
AGC_PKG_PRKG1_ST	Q8WZ42	TTN	Q13976	PRKG1	S5141	D5143N	5143	Missense	proximal	2	no	8.350	8.373	EPSD	ICGC;COSMIC	7.092	Up-regulation
AGC_PKG_PRKG1_ST	Q8WZ42	TTN	Q13976	PRKG1	S5141	K5142N	5142	Missense	proximal	1	no	8.350	8.100	EPSD	ICGC;COSMIC	7.092	Down-regulation
AGC_PKG_PRKG1_ST	Q8WZ42	TTN	Q13976	PRKG1	S5141	P5146S	5146	Missense	distal	5	no	8.350	8.422	EPSD	ICGC;COSMIC	7.092	Up-regulation
AGC_PKG_PRKG1_ST	Q8WZ42	TTN	Q13976	PRKG1	T5160	G5158R	5158	Missense	proximal	-2	no	4.789	8.276	EPSD	ICGC;COSMIC	7.092	Gain
AGC_PKG_PRKG1_ST	Q8WZ42	TTN	Q13976	PRKG1	T5160	Q5157R	5157	Missense	distal	-3	no	4.789	8.623	EPSD	ICGC;COSMIC	7.092	Gain
AGC_PKG_PRKG1_ST	Q8WZ42	TTN	Q13976	PRKG1	S5271	E5269K	5269	Missense	proximal	-2	no	5.927	9.449	EPSD	ICGC;COSMIC	7.092	Gain
AGC_PKG_PRKG1_ST	Q8WZ42	TTN	Q13976	PRKG1	S5276	S5280C	5280	Missense	distal	4	no	7.352	7.476	EPSD	ICGC;COSMIC	7.092	Up-regulation
AGC_PKG_PRKG1_ST	Q8WZ42	TTN	Q13976	PRKG1	S5276	S5276Y	5276	Missense	central	0	yes	7.352	0.000	EPSD	ICGC;COSMIC	7.092	Loss
AGC_PKG_PRKG1_ST	Q8WZ42	TTN	Q13976	PRKG1	S5276	E5279A	5279	Missense	distal	3	no	7.352	7.188	EPSD	ICGC;COSMIC	7.092	Down-regulation
AGC_PKG_PRKG1_ST	Q8WZ42	TTN	Q13976	PRKG1	S5276	S5280Y	5280	Missense	distal	4	no	7.352	7.502	EPSD	ICGC;COSMIC	7.092	Up-regulation
AGC_PKG_PRKG1_ST	Q8WZ42	TTN	Q13976	PRKG1	S5276	E5269K	5269	Missense	distal	-7	no	7.352	8.353	EPSD	ICGC;COSMIC	7.092	Up-regulation
AGC_PKG_PRKG1_ST	Q8WZ42	TTN	Q13976	PRKG1	S5276	E5279G	5279	Missense	distal	3	no	7.352	7.325	EPSD	ICGC;COSMIC	7.092	Down-regulation
AGC_PKG_PRKG1_ST	Q8WZ42	TTN	Q13976	PRKG1	S5276	T5281N	5281	Missense	distal	5	no	7.352	7.324	EPSD	ICGC;COSMIC	7.092	Down-regulation
AGC_PKG_PRKG1_ST	Q8WZ42	TTN	Q13976	PRKG1	S5276	R5274K	5274	Missense	proximal	-2	no	7.352	5.875	EPSD	ICGC;COSMIC	7.092	Loss
AGC_PKG_PRKG1_ST	Q8WZ42	TTN	Q13976	PRKG1	S5421	E5420D	5420	Missense	proximal	-1	no	7.986	7.943	EPSD	ICGC;COSMIC	7.092	Down-regulation
AGC_PKG_PRKG1_ST	Q8WZ42	TTN	Q13976	PRKG1	S5421	G5427E	5427	Missense	distal	6	no	7.986	8.049	EPSD	ICGC;COSMIC	7.092	Up-regulation
AGC_PKG_PRKG1_ST	Q8WZ42	TTN	Q13976	PRKG1	S5421	G5428A	5428	Missense	distal	7	no	7.986	8.038	EPSD	ICGC;COSMIC	7.092	Up-regulation
AGC_PKG_PRKG1_ST	Q8WZ42	TTN	Q13976	PRKG1	S5421	R5426Q	5426	Missense	distal	5	no	7.986	7.962	EPSD	ICGC;COSMIC	7.092	Down-regulation
AGC_PKG_PRKG1_ST	Q8WZ42	TTN	Q13976	PRKG1	S5421	I5419N	5419	Missense	proximal	-2	no	7.986	9.570	EPSD	ICGC;COSMIC	7.092	Up-regulation
AGC_PKG_PRKG1_ST	Q8WZ42	TTN	Q13976	PRKG1	S5421	T5422S	5422	Missense	proximal	1	no	7.986	8.037	EPSD	ICGC;COSMIC	7.092	Up-regulation
AGC_PKG_PRKG1_ST	Q8WZ42	TTN	Q13976	PRKG1	S5421	S5424F	5424	Missense	distal	3	no	7.986	8.169	EPSD	ICGC	7.092	Up-regulation
AGC_PKG_PRKG1_ST	Q8WZ42	TTN	Q13976	PRKG1	S5421	R5426W	5426	Missense	distal	5	no	7.986	7.886	EPSD	ICGC;COSMIC	7.092	Down-regulation
AGC_PKG_PRKG1_ST	Q8WZ42	TTN	Q13976	PRKG1	S5421	T5422I	5422	Missense	proximal	1	no	7.986	7.572	EPSD	ICGC	7.092	Down-regulation
AGC_PKG_PRKG1_ST	Q8WZ42	TTN	Q13976	PRKG1	S5497	Q5494E	5494	Missense	distal	-3	no	9.293	6.187	EPSD	ICGC;COSMIC	7.092	Loss
AGC_PKG_PRKG1_ST	Q8WZ42	TTN	Q13976	PRKG1	S5497	S5501L	5501	Missense	distal	4	no	9.293	9.544	EPSD	ICGC;COSMIC	7.092	Up-regulation
AGC_PKG_PRKG1_ST	Q8WZ42	TTN	Q13976	PRKG1	S5497	K5503E	5503	Missense	distal	6	no	9.293	9.510	EPSD	ICGC;COSMIC	7.092	Up-regulation
AGC_PKG_PRKG1_ST	Q8WZ42	TTN	Q13976	PRKG1	S5497	V5502L	5502	Missense	distal	5	no	9.293	9.241	EPSD	ICGC;COSMIC	7.092	Down-regulation
AGC_PKG_PRKG1_ST	Q8WZ42	TTN	Q13976	PRKG1	S5497	A5491E	5491	Missense	distal	-6	no	9.293	8.989	EPSD	ICGC;COSMIC	7.092	Down-regulation
AGC_PKG_PRKG1_ST	Q8WZ42	TTN	Q13976	PRKG1	S5497	A5498T	5498	Missense	proximal	1	no	9.293	9.255	EPSD	ICGC;COSMIC	7.092	Down-regulation
AGC_PKG_PRKG1_ST	Q8WZ42	TTN	Q13976	PRKG1	S5497	L5500I	5500	Missense	distal	3	no	9.293	9.244	EPSD	ICGC	7.092	Down-regulation
AGC_PKG_PRKG1_ST	Q8WZ42	TTN	Q13976	PRKG1	S5573	K5570R	5570	Missense	distal	-3	no	6.945	9.303	EPSD	ICGC;COSMIC	7.092	Gain
AGC_PKG_PRKG1_ST	Q8WZ42	TTN	Q13976	PRKG1	S5588	K5590N	5590	Missense	proximal	2	no	8.684	8.648	EPSD	ICGC;COSMIC	7.092	Down-regulation
AGC_PKG_PRKG1_ST	Q8WZ42	TTN	Q13976	PRKG1	S5588	S5587R	5587	Missense	proximal	-1	no	8.684	8.786	EPSD	ICGC;COSMIC	7.092	Up-regulation
AGC_PKG_PRKG1_ST	Q8WZ42	TTN	Q13976	PRKG1	S5588	D5583N	5583	Missense	distal	-5	no	8.684	8.602	EPSD	ICGC;COSMIC	7.092	Down-regulation
AGC_PKG_PRKG1_ST	Q8WZ42	TTN	Q13976	PRKG1	S5588	N5594I	5594	Missense	distal	6	no	8.684	8.873	EPSD	ICGC;COSMIC	7.092	Up-regulation
AGC_PKG_PRKG1_ST	Q8WZ42	TTN	Q13976	PRKG1	S5588	S5588R	5588	Missense	central	0	yes	8.684	0.000	EPSD	ICGC;COSMIC	7.092	Loss
AGC_PKG_PRKG1_ST	Q8WZ42	TTN	Q13976	PRKG1	S5588	V5584I	5584	Missense	distal	-4	no	8.684	8.375	EPSD	ICGC;COSMIC	7.092	Down-regulation
AGC_PKG_PRKG1_ST	Q8WZ42	TTN	Q13976	PRKG1	S5643	E5641K	5641	Missense	proximal	-2	no	4.047	7.569	EPSD	ICGC	7.092	Gain
AGC_PKG_PRKG1_ST	Q8WZ42	TTN	Q13976	PRKG1	S5703	Y5696H	5696	Missense	distal	-7	no	7.038	7.286	EPSD	ICGC;COSMIC	7.092	Gain
AGC_PKG_PRKG1_ST	Q8WZ42	TTN	Q13976	PRKG1	S5795	R5801M	5801	Missense	distal	6	no	10.523	10.649	EPSD	ICGC	7.092	Up-regulation
AGC_PKG_PRKG1_ST	Q8WZ42	TTN	Q13976	PRKG1	S5795	S5795R	5795	Missense	central	0	yes	10.523	0.000	EPSD	ICGC;COSMIC	7.092	Loss
AGC_PKG_PRKG1_ST	Q8WZ42	TTN	Q13976	PRKG1	S5795	R5801S	5801	Missense	distal	6	no	10.523	10.595	EPSD	ICGC;COSMIC	7.092	Up-regulation
AGC_PKG_PRKG1_ST	Q8WZ42	TTN	Q13976	PRKG1	S5795	N5802K	5802	Missense	distal	7	no	10.523	10.578	EPSD	ICGC;COSMIC	7.092	Up-regulation
AGC_PKG_PRKG1_ST	Q8WZ42	TTN	Q13976	PRKG1	S5795	L5798F	5798	Missense	distal	3	no	10.523	10.337	EPSD	ICGC;COSMIC	7.092	Down-regulation
AGC_PKG_PRKG1_ST	Q8WZ42	TTN	Q13976	PRKG1	S5795	P5794L	5794	Missense	proximal	-1	no	10.523	10.426	EPSD	ICGC	7.092	Down-regulation
AGC_PKG_PRKG1_ST	Q8WZ42	TTN	Q13976	PRKG1	S5795	Q5789R	5789	Missense	distal	-6	no	10.523	10.820	EPSD	ICGC	7.092	Up-regulation
AGC_PKG_PRKG1_ST	Q8WZ42	TTN	Q13976	PRKG1	S5805	N5802K	5802	Missense	distal	-3	no	3.516	8.063	EPSD	ICGC;COSMIC	7.092	Gain
AGC_PKG_PRKG1_ST	Q8WZ42	TTN	Q13976	PRKG1	S6076	D6083Y	6083	Missense	distal	7	no	7.774	7.792	EPSD	ICGC;COSMIC	7.092	Up-regulation
AGC_PKG_PRKG1_ST	Q8WZ42	TTN	Q13976	PRKG1	S6076	V6071A	6071	Missense	distal	-5	no	7.774	7.649	EPSD	ICGC;COSMIC	7.092	Down-regulation
AGC_PKG_PRKG1_ST	Q8WZ42	TTN	Q13976	PRKG1	S6076	T6080K	6080	Missense	distal	4	no	7.774	7.756	EPSD	ICGC	7.092	Down-regulation
AGC_PKG_PRKG1_ST	Q8WZ42	TTN	Q13976	PRKG1	S6076	V6071I	6071	Missense	distal	-5	no	7.774	7.876	EPSD	ICGC;COSMIC	7.092	Up-regulation
AGC_PKG_PRKG1_ST	Q8WZ42	TTN	Q13976	PRKG1	S6076	E6081D	6081	Missense	distal	5	no	7.774	7.764	EPSD	ICGC;COSMIC	7.092	Down-regulation
AGC_PKG_PRKG1_ST	Q8WZ42	TTN	Q13976	PRKG1	S6135	S6129P	6129	Missense	distal	-6	no	7.965	7.649	EPSD	ICGC;COSMIC	7.092	Down-regulation
AGC_PKG_PRKG1_ST	Q8WZ42	TTN	Q13976	PRKG1	S6135	M6131I	6131	Missense	distal	-4	no	7.965	7.259	EPSD	ICGC;COSMIC	7.092	Down-regulation
AGC_PKG_PRKG1_ST	Q8WZ42	TTN	Q13976	PRKG1	S6205	E6203K	6203	Missense	proximal	-2	no	4.175	7.697	EPSD	ICGC;COSMIC	7.092	Gain
AGC_PKG_PRKG1_ST	Q8WZ42	TTN	Q13976	PRKG1	T6328	Q6326R	6326	Missense	proximal	-2	no	4.539	7.504	EPSD	ICGC;COSMIC	7.092	Gain
AGC_PKG_PRKG1_ST	Q8WZ42	TTN	Q13976	PRKG1	T6332	C6329R	6329	Missense	distal	-3	no	1.689	8.711	EPSD	ICGC;COSMIC	7.092	Gain
AGC_PKG_PRKG1_ST	Q8WZ42	TTN	Q13976	PRKG1	S6339	S6337R	6337	Missense	proximal	-2	no	4.854	8.262	EPSD	ICGC;COSMIC	7.092	Gain
AGC_PKG_PRKG1_ST	Q8WZ42	TTN	Q13976	PRKG1	S6920	H6922N	6922	Missense	proximal	2	no	9.306	9.296	EPSD	ICGC;COSMIC	7.092	Down-regulation
AGC_PKG_PRKG1_ST	Q8WZ42	TTN	Q13976	PRKG1	S6920	A6913D	6913	Missense	distal	-7	no	9.306	8.402	EPSD	ICGC;COSMIC	7.092	Down-regulation
AGC_PKG_PRKG1_ST	Q8WZ42	TTN	Q13976	PRKG1	S6920	H6922Y	6922	Missense	proximal	2	no	9.306	9.268	EPSD	ICGC;COSMIC	7.092	Down-regulation
AGC_PKG_PRKG1_ST	Q8WZ42	TTN	Q13976	PRKG1	S6920	G6927R	6927	Missense	distal	7	no	9.306	9.418	EPSD	ICGC;COSMIC	7.092	Up-regulation
AGC_PKG_PRKG1_ST	Q8WZ42	TTN	Q13976	PRKG1	S6920	L6919V	6919	Missense	proximal	-1	no	9.306	9.393	EPSD	ICGC;COSMIC	7.092	Up-regulation
AGC_PKG_PRKG1_ST	Q8WZ42	TTN	Q13976	PRKG1	S6920	A6913T	6913	Missense	distal	-7	no	9.306	9.251	EPSD	ICGC	7.092	Down-regulation
AGC_PKG_PRKG1_ST	Q8WZ42	TTN	Q13976	PRKG1	S6920	R6918I	6918	Missense	proximal	-2	no	9.306	3.301	EPSD	ICGC;COSMIC	7.092	Loss
AGC_PKG_PRKG1_ST	Q8WZ42	TTN	Q13976	PRKG1	S7265	L7258R	7258	Missense	distal	-7	no	5.473	7.488	EPSD	ICGC	7.092	Gain
AGC_PKG_PRKG1_ST	Q8WZ42	TTN	Q13976	PRKG1	S7265	G7263R	7263	Missense	proximal	-2	no	5.473	8.960	EPSD	ICGC;COSMIC	7.092	Gain
AGC_PKG_PRKG1_ST	Q8WZ42	TTN	Q13976	PRKG1	S7308	A7303T	7303	Missense	distal	-5	no	8.075	8.085	EPSD	ICGC;COSMIC	7.092	Up-regulation
AGC_PKG_PRKG1_ST	Q8WZ42	TTN	Q13976	PRKG1	S7308	E7307G	7307	Missense	proximal	-1	no	8.075	8.131	EPSD	ICGC;COSMIC	7.092	Up-regulation
AGC_PKG_PRKG1_ST	Q8WZ42	TTN	Q13976	PRKG1	S7308	A7303S	7303	Missense	distal	-5	no	8.075	8.076	EPSD	ICGC;COSMIC	7.092	Up-regulation
AGC_PKG_PRKG1_ST	Q8WZ42	TTN	Q13976	PRKG1	S7308	A7303V	7303	Missense	distal	-5	no	8.075	8.200	EPSD	ICGC;COSMIC	7.092	Up-regulation
AGC_PKG_PRKG1_ST	Q8WZ42	TTN	Q13976	PRKG1	S7308	G7306V	7306	Missense	proximal	-2	no	8.075	7.604	EPSD	ICGC;COSMIC	7.092	Down-regulation
AGC_PKG_PRKG1_ST	Q8WZ42	TTN	Q13976	PRKG1	S7308	I7315T	7315	Missense	distal	7	no	8.075	8.210	EPSD	ICGC;COSMIC	7.092	Up-regulation
AGC_PKG_PRKG1_ST	Q8WZ42	TTN	Q13976	PRKG1	S7330	L7332R	7332	Missense	proximal	2	no	9.896	10.027	EPSD	ICGC	7.092	Up-regulation
AGC_PKG_PRKG1_ST	Q8WZ42	TTN	Q13976	PRKG1	S7330	H7333R	7333	Missense	distal	3	no	9.896	9.741	EPSD	ICGC;COSMIC	7.092	Down-regulation
AGC_PKG_PRKG1_ST	Q8WZ42	TTN	Q13976	PRKG1	S7330	E7334K	7334	Missense	distal	4	no	9.896	9.781	EPSD	ICGC;COSMIC	7.092	Down-regulation
AGC_PKG_PRKG1_ST	Q8WZ42	TTN	Q13976	PRKG1	S7330	R7327Q	7327	Missense	distal	-3	no	9.896	6.061	EPSD	ICGC;COSMIC	7.092	Loss
AGC_PKG_PRKG1_ST	Q8WZ42	TTN	Q13976	PRKG1	S7330	F7326L	7326	Missense	distal	-4	no	9.896	9.570	EPSD	ICGC;COSMIC	7.092	Down-regulation
AGC_PKG_PRKG1_ST	Q8WZ42	TTN	Q13976	PRKG1	S7330	F7326S	7326	Missense	distal	-4	no	9.896	10.343	EPSD	ICGC;COSMIC	7.092	Up-regulation
AGC_PKG_PRKG1_ST	Q8WZ42	TTN	Q13976	PRKG1	S7330	D7329N	7329	Missense	proximal	-1	no	9.896	9.973	EPSD	ICGC	7.092	Up-regulation
AGC_PKG_PRKG1_ST	Q8WZ42	TTN	Q13976	PRKG1	S7330	E7331K	7331	Missense	proximal	1	no	9.896	10.203	EPSD	ICGC;COSMIC	7.092	Up-regulation
AGC_PKG_PRKG1_ST	Q8WZ42	TTN	Q13976	PRKG1	S7330	S7324L	7324	Missense	distal	-6	no	9.896	9.270	EPSD	ICGC;COSMIC	7.092	Down-regulation
AGC_PKG_PRKG1_ST	Q8WZ42	TTN	Q13976	PRKG1	S7335	L7332R	7332	Missense	distal	-3	no	1.804	8.948	EPSD	ICGC	7.092	Gain
AGC_PKG_PRKG1_ST	Q8WZ42	TTN	Q13976	PRKG1	S7485	V7481M	7481	Missense	distal	-4	no	7.912	8.309	EPSD	ICGC;COSMIC	7.092	Up-regulation
AGC_PKG_PRKG1_ST	Q8WZ42	TTN	Q13976	PRKG1	S7485	L7490I	7490	Missense	distal	5	no	7.912	7.927	EPSD	ICGC;COSMIC	7.092	Up-regulation
AGC_PKG_PRKG1_ST	Q8WZ42	TTN	Q13976	PRKG1	S7485	G7492V	7492	Missense	distal	7	no	7.912	7.892	EPSD	ICGC;COSMIC	7.092	Down-regulation
AGC_PKG_PRKG1_ST	Q8WZ42	TTN	Q13976	PRKG1	S7485	G7492E	7492	Missense	distal	7	no	7.912	7.897	EPSD	ICGC	7.092	Down-regulation
AGC_PKG_PRKG1_ST	Q8WZ42	TTN	Q13976	PRKG1	S7485	R7479Q	7479	Missense	distal	-6	no	7.912	7.615	EPSD	ICGC;COSMIC	7.092	Down-regulation
AGC_PKG_PRKG1_ST	Q8WZ42	TTN	Q13976	PRKG1	S7522	I7519T	7519	Missense	distal	-3	no	5.057	8.399	EPSD	ICGC;COSMIC	7.092	Gain
AGC_PKG_PRKG1_ST	Q8WZ42	TTN	Q13976	PRKG1	S7563	T7567N	7567	Missense	distal	4	no	9.410	9.468	EPSD	ICGC	7.092	Up-regulation
AGC_PKG_PRKG1_ST	Q8WZ42	TTN	Q13976	PRKG1	S7563	A7557T	7557	Missense	distal	-6	no	9.410	9.371	EPSD	ICGC;COSMIC	7.092	Down-regulation
AGC_PKG_PRKG1_ST	Q8WZ42	TTN	Q13976	PRKG1	S7563	E7561K	7561	Missense	proximal	-2	no	9.410	12.933	EPSD	ICGC	7.092	Up-regulation
AGC_PKG_PRKG1_ST	Q8WZ42	TTN	Q13976	PRKG1	S7563	D7556N	7556	Missense	distal	-7	no	9.410	9.865	EPSD	ICGC;COSMIC	7.092	Up-regulation
AGC_PKG_PRKG1_ST	Q8WZ42	TTN	Q13976	PRKG1	S7563	M7559I	7559	Missense	distal	-4	no	9.410	8.704	EPSD	ICGC;COSMIC	7.092	Down-regulation
AGC_PKG_PRKG1_ST	Q8WZ42	TTN	Q13976	PRKG1	S7563	E7561A	7561	Missense	proximal	-2	no	9.410	10.955	EPSD	ICGC;COSMIC	7.092	Up-regulation
AGC_PKG_PRKG1_ST	Q8WZ42	TTN	Q13976	PRKG1	S7613	R7610K	7610	Missense	distal	-3	no	8.208	5.850	EPSD	ICGC;COSMIC	7.092	Loss
AGC_PKG_PRKG1_ST	Q8WZ42	TTN	Q13976	PRKG1	S7613	H7618Y	7618	Missense	distal	5	no	8.208	8.177	EPSD	ICGC	7.092	Down-regulation
AGC_PKG_PRKG1_ST	Q8WZ42	TTN	Q13976	PRKG1	S7613	I7620V	7620	Missense	distal	7	no	8.208	8.261	EPSD	ICGC;COSMIC	7.092	Up-regulation
AGC_PKG_PRKG1_ST	Q8WZ42	TTN	Q13976	PRKG1	S7613	R7610T	7610	Missense	distal	-3	no	8.208	3.042	EPSD	ICGC;COSMIC	7.092	Loss
AGC_PKG_PRKG1_ST	Q8WZ42	TTN	Q13976	PRKG1	S7613	G7609R	7609	Missense	distal	-4	no	8.208	8.891	EPSD	ICGC;COSMIC	7.092	Up-regulation
AGC_PKG_PRKG1_ST	Q8WZ42	TTN	Q13976	PRKG1	S7613	F7606L	7606	Missense	distal	-7	no	8.208	7.469	EPSD	ICGC;COSMIC;CCLE	7.092	Down-regulation
AGC_PKG_PRKG1_ST	Q8WZ42	TTN	Q13976	PRKG1	S7637	E7635K	7635	Missense	proximal	-2	no	3.991	7.514	EPSD	ICGC;COSMIC	7.092	Gain
AGC_PKG_PRKG1_ST	Q8WZ42	TTN	Q13976	PRKG1	S7662	H7660R	7660	Missense	proximal	-2	no	3.918	8.175	EPSD	ICGC;COSMIC	7.092	Gain
AGC_PKG_PRKG1_ST	Q8WZ42	TTN	Q13976	PRKG1	S7684	L7681R	7681	Missense	distal	-3	no	2.324	9.469	EPSD	ICGC	7.092	Gain
AGC_PKG_PRKG1_ST	Q8WZ42	TTN	Q13976	PRKG1	S7989	A7992T	7992	Missense	distal	3	no	7.261	7.229	EPSD	ICGC;COSMIC	7.092	Down-regulation
AGC_PKG_PRKG1_ST	Q8WZ42	TTN	Q13976	PRKG1	S7989	P7991T	7991	Missense	proximal	2	no	7.261	7.328	EPSD	ICGC;COSMIC	7.092	Up-regulation
AGC_PKG_PRKG1_ST	Q8WZ42	TTN	Q13976	PRKG1	S7989	Y7993H	7993	Missense	distal	4	no	7.261	7.194	EPSD	ICGC;COSMIC	7.092	Down-regulation
AGC_PKG_PRKG1_ST	Q8WZ42	TTN	Q13976	PRKG1	S7989	R7988Q	7988	Missense	proximal	-1	no	7.261	7.197	EPSD	ICGC;COSMIC	7.092	Down-regulation
AGC_PKG_PRKG1_ST	Q8WZ42	TTN	Q13976	PRKG1	S7989	M7995I	7995	Missense	distal	6	no	7.261	7.540	EPSD	ICGC;COSMIC	7.092	Up-regulation
AGC_PKG_PRKG1_ST	Q8WZ42	TTN	Q13976	PRKG1	S7989	E7983K	7983	Missense	distal	-6	no	7.261	7.742	EPSD	ICGC;COSMIC	7.092	Up-regulation
AGC_PKG_PRKG1_ST	Q8WZ42	TTN	Q13976	PRKG1	S8426	L8425F	8425	Missense	proximal	-1	no	7.434	7.541	EPSD	ICGC;COSMIC	7.092	Up-regulation
AGC_PKG_PRKG1_ST	Q8WZ42	TTN	Q13976	PRKG1	S8426	S8429Y	8429	Missense	distal	3	no	7.434	7.625	EPSD	ICGC;COSMIC	7.092	Up-regulation
AGC_PKG_PRKG1_ST	Q8WZ42	TTN	Q13976	PRKG1	S8426	K8424N	8424	Missense	proximal	-2	no	7.434	4.490	EPSD	ICGC;COSMIC	7.092	Loss
AGC_PKG_PRKG1_ST	Q8WZ42	TTN	Q13976	PRKG1	S8426	D8427E	8427	Missense	proximal	1	no	7.434	7.508	EPSD	ICGC	7.092	Up-regulation
AGC_PKG_PRKG1_ST	Q8WZ42	TTN	Q13976	PRKG1	S8426	S8429C	8429	Missense	distal	3	no	7.434	7.591	EPSD	ICGC;COSMIC	7.092	Up-regulation
AGC_PKG_PRKG1_ST	Q8WZ42	TTN	Q13976	PRKG1	S8426	K8424Q	8424	Missense	proximal	-2	no	7.434	5.946	EPSD	ICGC;COSMIC	7.092	Loss
AGC_PKG_PRKG1_ST	Q8WZ42	TTN	Q13976	PRKG1	S8426	S8429F	8429	Missense	distal	3	no	7.434	7.616	EPSD	ICGC	7.092	Up-regulation
AGC_PKG_PRKG1_ST	Q8WZ42	TTN	Q13976	PRKG1	S8426	S8426I	8426	Missense	central	0	yes	7.434	0.000	EPSD	ICGC;COSMIC	7.092	Loss
AGC_PKG_PRKG1_ST	Q8WZ42	TTN	Q13976	PRKG1	S8740	V8743L	8743	Missense	distal	3	no	7.356	7.498	EPSD	ICGC;COSMIC	7.092	Up-regulation
AGC_PKG_PRKG1_ST	Q8WZ42	TTN	Q13976	PRKG1	S8740	P8744T	8744	Missense	distal	4	no	7.356	7.228	EPSD	ICGC;COSMIC;CCLE	7.092	Down-regulation
AGC_PKG_PRKG1_ST	Q8WZ42	TTN	Q13976	PRKG1	S8740	E8741D	8741	Missense	proximal	1	no	7.356	7.282	EPSD	ICGC;COSMIC	7.092	Down-regulation
AGC_PKG_PRKG1_ST	Q8WZ42	TTN	Q13976	PRKG1	S8740	G8738S	8738	Missense	proximal	-2	no	7.356	7.436	EPSD	ICGC	7.092	Up-regulation
AGC_PKG_PRKG1_ST	Q8WZ42	TTN	Q13976	PRKG1	S8740	S8734N	8734	Missense	distal	-6	no	7.356	7.075	EPSD	ICGC	7.092	Loss
AGC_PKG_PRKG1_ST	Q8WZ42	TTN	Q13976	PRKG1	S9117	G9124R	9124	Missense	distal	7	no	7.162	7.275	EPSD	ICGC;COSMIC	7.092	Up-regulation
AGC_PKG_PRKG1_ST	Q8WZ42	TTN	Q13976	PRKG1	S9117	S9112R	9112	Missense	distal	-5	no	7.162	7.022	EPSD	ICGC	7.092	Loss
AGC_PKG_PRKG1_ST	Q8WZ42	TTN	Q13976	PRKG1	S9117	G9123S	9123	Missense	distal	6	no	7.162	7.019	EPSD	ICGC	7.092	Loss
AGC_PKG_PRKG1_ST	Q8WZ42	TTN	Q13976	PRKG1	S9117	G9123C	9123	Missense	distal	6	no	7.162	7.198	EPSD	ICGC;COSMIC	7.092	Up-regulation
AGC_PKG_PRKG1_ST	Q8WZ42	TTN	Q13976	PRKG1	S9117	G9123D	9123	Missense	distal	6	no	7.162	7.252	EPSD	ICGC;COSMIC	7.092	Up-regulation
AGC_PKG_PRKG1_ST	Q8WZ42	TTN	Q13976	PRKG1	S9117	A9114P	9114	Missense	distal	-3	no	7.162	6.839	EPSD	ICGC;COSMIC	7.092	Loss
AGC_PKG_PRKG1_ST	Q8WZ42	TTN	Q13976	PRKG1	S9117	R9121Q	9121	Missense	distal	4	no	7.162	7.222	EPSD	ICGC;COSMIC	7.092	Up-regulation
AGC_PKG_PRKG1_ST	Q8WZ42	TTN	Q13976	PRKG1	S9117	R9118K	9118	Missense	proximal	1	no	7.162	7.033	EPSD	ICGC;COSMIC	7.092	Loss
AGC_PKG_PRKG1_ST	Q8WZ42	TTN	Q13976	PRKG1	S9117	D9116N	9116	Missense	proximal	-1	no	7.162	7.240	EPSD	ICGC;COSMIC	7.092	Up-regulation
AGC_PKG_PRKG1_ST	Q8WZ42	TTN	Q13976	PRKG1	S9147	G9145R	9145	Missense	proximal	-2	no	5.390	8.877	EPSD	ICGC;COSMIC	7.092	Gain
AGC_PKG_PRKG1_ST	Q8WZ42	TTN	Q13976	PRKG1	S9183	S9177R	9177	Missense	distal	-6	no	11.457	11.754	EPSD	ICGC;COSMIC	7.092	Up-regulation
AGC_PKG_PRKG1_ST	Q8WZ42	TTN	Q13976	PRKG1	S9183	E9187K	9187	Missense	distal	4	no	11.457	11.341	EPSD	ICGC;COSMIC	7.092	Down-regulation
AGC_PKG_PRKG1_ST	Q8WZ42	TTN	Q13976	PRKG1	S9183	T9185A	9185	Missense	proximal	2	no	11.457	11.464	EPSD	ICGC;COSMIC	7.092	Up-regulation
AGC_PKG_PRKG1_ST	Q8WZ42	TTN	Q13976	PRKG1	S9183	R9181T	9181	Missense	proximal	-2	no	11.457	7.865	EPSD	ICGC;COSMIC;CCLE	7.092	Down-regulation
AGC_PKG_PRKG1_ST	Q8WZ42	TTN	Q13976	PRKG1	S9578	L9585R	9585	Missense	distal	7	no	11.799	12.005	EPSD	ICGC;CCLE	7.092	Up-regulation
AGC_PKG_PRKG1_ST	Q8WZ42	TTN	Q13976	PRKG1	S10146	T10148I	10148	Missense	proximal	2	no	7.825	7.730	EPSD	ICGC;COSMIC	7.092	Down-regulation
AGC_PKG_PRKG1_ST	Q8WZ42	TTN	Q13976	PRKG1	S10146	V10141L	10141	Missense	distal	-5	no	7.825	7.938	EPSD	ICGC;COSMIC	7.092	Up-regulation
AGC_PKG_PRKG1_ST	Q8WZ42	TTN	Q13976	PRKG1	S10146	R10147Q	10147	Missense	proximal	1	no	7.825	7.661	EPSD	ICGC;COSMIC	7.092	Down-regulation
AGC_PKG_PRKG1_ST	Q8WZ42	TTN	Q13976	PRKG1	S10146	K10144R	10144	Missense	proximal	-2	no	7.825	9.303	EPSD	ICGC;COSMIC	7.092	Up-regulation
AGC_PKG_PRKG1_ST	Q8WZ42	TTN	Q13976	PRKG1	S10146	Q10151H	10151	Missense	distal	5	no	7.825	7.800	EPSD	ICGC;COSMIC	7.092	Down-regulation
AGC_PKG_PRKG1_ST	Q8WZ42	TTN	Q13976	PRKG1	S10321	S10321A	10321	Missense	central	0	yes	8.406	0.000	EPSD	ICGC	7.092	Loss
AGC_PKG_PRKG1_ST	Q8WZ42	TTN	Q13976	PRKG1	S10321	A10325E	10325	Missense	distal	4	no	8.406	8.506	EPSD	ICGC	7.092	Up-regulation
AGC_PKG_PRKG1_ST	Q8WZ42	TTN	Q13976	PRKG1	S10321	R10318K	10318	Missense	distal	-3	no	8.406	6.048	EPSD	ICGC;COSMIC	7.092	Loss
AGC_PKG_PRKG1_ST	Q8WZ42	TTN	Q13976	PRKG1	S10321	R10318I	10318	Missense	distal	-3	no	8.406	-0.100	EPSD	ICGC;COSMIC	7.092	Loss
AGC_PKG_PRKG1_ST	Q8WZ42	TTN	Q13976	PRKG1	S10633	E10630K	10630	Missense	distal	-3	no	3.741	8.324	EPSD	ICGC	7.092	Gain
AGC_PKG_PRKG1_ST	Q8WZ42	TTN	Q13976	PRKG1	T10658	E10660Q	10660	Missense	proximal	2	no	8.296	8.355	EPSD	ICGC	7.092	Up-regulation
AGC_PKG_PRKG1_ST	Q8WZ42	TTN	Q13976	PRKG1	T10658	T10658N	10658	Missense	central	0	yes	8.296	0.000	EPSD	ICGC	7.092	Loss
AGC_PKG_PRKG1_ST	Q8WZ42	TTN	Q13976	PRKG1	T10658	E10662A	10662	Missense	distal	4	no	8.296	8.196	EPSD	ICGC;COSMIC	7.092	Down-regulation
AGC_PKG_PRKG1_ST	Q8WZ42	TTN	Q13976	PRKG1	T10658	R10655K	10655	Missense	distal	-3	no	8.296	5.938	EPSD	ICGC	7.092	Loss
AGC_PKG_PRKG1_ST	Q8WZ42	TTN	Q13976	PRKG1	T10658	A10663V	10663	Missense	distal	5	no	8.296	8.246	EPSD	ICGC;COSMIC	7.092	Down-regulation
AGC_PKG_PRKG1_ST	Q8WZ42	TTN	Q13976	PRKG1	T10658	S10665L	10665	Missense	distal	7	no	8.296	8.128	EPSD	ICGC;COSMIC	7.092	Down-regulation
AGC_PKG_PRKG1_ST	Q8WZ42	TTN	Q13976	PRKG1	T10658	E10651K	10651	Missense	distal	-7	no	8.296	9.297	EPSD	ICGC;COSMIC	7.092	Up-regulation
AGC_PKG_PRKG1_ST	Q8WZ42	TTN	Q13976	PRKG1	T10658	Y10657D	10657	Missense	proximal	-1	no	8.296	8.226	EPSD	ICGC;COSMIC	7.092	Down-regulation
AGC_PKG_PRKG1_ST	Q8WZ42	TTN	Q13976	PRKG1	T10658	E10652D	10652	Missense	distal	-6	no	8.296	8.152	EPSD	ICGC;COSMIC	7.092	Down-regulation
AGC_PKG_PRKG1_ST	Q8WZ42	TTN	Q13976	PRKG1	T10791	E10788K	10788	Missense	distal	-3	no	2.764	7.347	EPSD	ICGC	7.092	Gain
AGC_PKG_PRKG1_ST	Q8WZ42	TTN	Q13976	PRKG1	S11223	P11227T	11227	Missense	distal	4	no	7.439	7.311	EPSD	ICGC;COSMIC	7.092	Down-regulation
AGC_PKG_PRKG1_ST	Q8WZ42	TTN	Q13976	PRKG1	S11223	K11225N	11225	Missense	proximal	2	no	7.439	7.402	EPSD	ICGC;COSMIC	7.092	Down-regulation
AGC_PKG_PRKG1_ST	Q8WZ42	TTN	Q13976	PRKG1	S11223	E11229K	11229	Missense	distal	6	no	7.439	7.222	EPSD	ICGC;COSMIC	7.092	Down-regulation
AGC_PKG_PRKG1_ST	Q8WZ42	TTN	Q13976	PRKG1	S11223	V11222M	11222	Missense	proximal	-1	no	7.439	7.543	EPSD	ICGC;COSMIC	7.092	Up-regulation
AGC_PKG_PRKG1_ST	Q8WZ42	TTN	Q13976	PRKG1	S11223	E11216G	11216	Missense	distal	-7	no	7.439	7.757	EPSD	ICGC;COSMIC	7.092	Up-regulation
AGC_PKG_PRKG1_ST	Q8WZ42	TTN	Q13976	PRKG1	S11503	P11499T	11499	Missense	distal	-4	no	8.100	8.404	EPSD	ICGC	7.092	Up-regulation
AGC_PKG_PRKG1_ST	Q8WZ42	TTN	Q13976	PRKG1	S11503	E11510D	11510	Missense	distal	7	no	8.100	8.085	EPSD	ICGC	7.092	Down-regulation
AGC_PKG_PRKG1_ST	Q8WZ42	TTN	Q13976	PRKG1	S12009	E12014K	12014	Missense	distal	5	no	7.621	7.683	EPSD	ICGC;COSMIC;CCLE	7.092	Up-regulation
AGC_PKG_PRKG1_ST	Q8WZ42	TTN	Q13976	PRKG1	S12009	E12012A	12012	Missense	distal	3	no	7.621	7.456	EPSD	ICGC;COSMIC	7.092	Down-regulation
AGC_PKG_PRKG1_ST	Q8WZ42	TTN	Q13976	PRKG1	S12009	K12006N	12006	Missense	distal	-3	no	7.621	3.074	EPSD	ICGC;COSMIC	7.092	Loss
AGC_PKG_PRKG1_ST	Q8WZ42	TTN	Q13976	PRKG1	S12009	A12013T	12013	Missense	distal	4	no	7.621	7.623	EPSD	ICGC;COSMIC	7.092	Up-regulation
AGC_PKG_PRKG1_ST	Q8WZ42	TTN	Q13976	PRKG1	S12022	G12021E	12021	Missense	proximal	-1	no	10.899	10.844	EPSD	ICGC;COSMIC	7.092	Down-regulation
AGC_PKG_PRKG1_ST	Q8WZ42	TTN	Q13976	PRKG1	S12022	P12027H	12027	Missense	distal	5	no	10.899	10.944	EPSD	ICGC;COSMIC	7.092	Up-regulation
AGC_PKG_PRKG1_ST	Q8WZ42	TTN	Q13976	PRKG1	S12022	P12027T	12027	Missense	distal	5	no	10.899	10.966	EPSD	ICGC;COSMIC	7.092	Up-regulation
AGC_PKG_PRKG1_ST	Q8WZ42	TTN	Q13976	PRKG1	S12491	K12488N	12488	Missense	distal	-3	no	9.038	4.492	EPSD	ICGC;COSMIC	7.092	Loss
AGC_PKG_PRKG1_ST	Q8WZ42	TTN	Q13976	PRKG1	S12491	R12493W	12493	Missense	proximal	2	no	9.038	8.938	EPSD	ICGC;COSMIC	7.092	Down-regulation
AGC_PKG_PRKG1_ST	Q8WZ42	TTN	Q13976	PRKG1	S12491	R12493Q	12493	Missense	proximal	2	no	9.038	9.032	EPSD	ICGC;COSMIC	7.092	Down-regulation
AGC_PKG_PRKG1_ST	Q8WZ42	TTN	Q13976	PRKG1	S12491	G12498S	12498	Missense	distal	7	no	9.038	9.112	EPSD	ICGC;COSMIC	7.092	Up-regulation
AGC_PKG_PRKG1_ST	Q8WZ42	TTN	Q13976	PRKG1	S12900	S12900L	12900	Missense	central	0	yes	7.652	0.000	EPSD	ICGC;COSMIC	7.092	Loss
AGC_PKG_PRKG1_ST	Q8WZ42	TTN	Q13976	PRKG1	S12900	R12894L	12894	Missense	distal	-6	no	7.652	6.729	EPSD	ICGC;COSMIC	7.092	Loss
AGC_PKG_PRKG1_ST	Q8WZ42	TTN	Q13976	PRKG1	S12900	E12906K	12906	Missense	distal	6	no	7.652	7.435	EPSD	ICGC;COSMIC	7.092	Down-regulation
AGC_PKG_PRKG1_ST	Q8WZ42	TTN	Q13976	PRKG1	S12900	R12894H	12894	Missense	distal	-6	no	7.652	7.128	EPSD	ICGC;COSMIC;CCLE	7.092	Down-regulation
AGC_PKG_PRKG1_ST	Q8WZ42	TTN	Q13976	PRKG1	S12900	Q12893K	12893	Missense	distal	-7	no	7.652	7.863	EPSD	ICGC;COSMIC	7.092	Up-regulation
AGC_PKG_PRKG1_ST	Q8WZ42	TTN	Q13976	PRKG1	S12900	G12907E	12907	Missense	distal	7	no	7.652	7.638	EPSD	ICGC;COSMIC	7.092	Down-regulation
AGC_PKG_PRKG1_ST	Q8WZ42	TTN	Q13976	PRKG1	S12902	S12900L	12900	Missense	proximal	-2	no	8.760	6.874	EPSD	ICGC;COSMIC	7.092	Loss
AGC_PKG_PRKG1_ST	Q8WZ42	TTN	Q13976	PRKG1	S12902	E12906K	12906	Missense	distal	4	no	8.760	8.645	EPSD	ICGC;COSMIC	7.092	Down-regulation
AGC_PKG_PRKG1_ST	Q8WZ42	TTN	Q13976	PRKG1	S12902	G12907E	12907	Missense	distal	5	no	8.760	8.755	EPSD	ICGC;COSMIC	7.092	Down-regulation
AGC_PKG_PRKG1_ST	Q8WZ42	TTN	Q13976	PRKG1	S12911	E12906K	12906	Missense	distal	-5	no	7.122	6.942	EPSD	ICGC;COSMIC	7.092	Loss
AGC_PKG_PRKG1_ST	Q8WZ42	TTN	Q13976	PRKG1	S12911	K12915E	12915	Missense	distal	4	no	7.122	7.238	EPSD	ICGC;COSMIC	7.092	Up-regulation
AGC_PKG_PRKG1_ST	Q8WZ42	TTN	Q13976	PRKG1	S12911	G12907E	12907	Missense	distal	-4	no	7.122	6.840	EPSD	ICGC;COSMIC	7.092	Loss
AGC_PKG_PRKG1_ST	Q8WZ42	TTN	Q13976	PRKG1	S12911	S12911L	12911	Missense	central	0	yes	7.122	0.000	EPSD	ICGC;COSMIC	7.092	Loss
AGC_PKG_PRKG1_ST	Q8WZ42	TTN	Q13976	PRKG1	S12911	I12912T	12912	Missense	proximal	1	no	7.122	7.536	EPSD	ICGC;COSMIC	7.092	Up-regulation
AGC_PKG_PRKG1_ST	Q8WZ42	TTN	Q13976	PRKG1	S12911	D12916N	12916	Missense	distal	5	no	7.122	7.157	EPSD	ICGC;COSMIC	7.092	Up-regulation
AGC_PKG_PRKG1_ST	Q8WZ42	TTN	Q13976	PRKG1	S12911	S12911P	12911	Missense	central	0	yes	7.122	0.000	EPSD	ICGC;COSMIC	7.092	Loss
AGC_PKG_PRKG1_ST	Q8WZ42	TTN	Q13976	PRKG1	S13113	R13117Q	13117	Missense	distal	4	no	7.486	7.546	EPSD	ICGC;COSMIC	7.092	Up-regulation
AGC_PKG_PRKG1_ST	Q8WZ42	TTN	Q13976	PRKG1	S13113	P13120A	13120	Missense	distal	7	no	7.486	7.566	EPSD	ICGC;COSMIC	7.092	Up-regulation
AGC_PKG_PRKG1_ST	Q8WZ42	TTN	Q13976	PRKG1	S13113	P13120Q	13120	Missense	distal	7	no	7.486	7.584	EPSD	ICGC	7.092	Up-regulation
AGC_PKG_PRKG1_ST	Q8WZ42	TTN	Q13976	PRKG1	S13113	A13107D	13107	Missense	distal	-6	no	7.486	7.038	EPSD	ICGC	7.092	Loss
AGC_PKG_PRKG1_ST	Q8WZ42	TTN	Q13976	PRKG1	S13113	P13120T	13120	Missense	distal	7	no	7.486	7.576	EPSD	ICGC;COSMIC	7.092	Up-regulation
AGC_PKG_PRKG1_ST	Q8WZ42	TTN	Q13976	PRKG1	S13113	S13112Y	13112	Missense	proximal	-1	no	7.486	7.394	EPSD	ICGC;COSMIC	7.092	Down-regulation
AGC_PKG_PRKG1_ST	Q8WZ42	TTN	Q13976	PRKG1	S13113	H13115N	13115	Missense	proximal	2	no	7.486	7.476	EPSD	ICGC;COSMIC	7.092	Down-regulation
AGC_PKG_PRKG1_ST	Q8WZ42	TTN	Q13976	PRKG1	S13113	P13120S	13120	Missense	distal	7	no	7.486	7.588	EPSD	ICGC;COSMIC	7.092	Up-regulation
AGC_PKG_PRKG1_ST	Q8WZ42	TTN	Q13976	PRKG1	S13172	P13170R	13170	Missense	proximal	-2	no	3.595	7.354	EPSD	ICGC;COSMIC	7.092	Gain
AGC_PKG_PRKG1_ST	Q8WZ42	TTN	Q13976	PRKG1	T13178	G13174V	13174	Missense	distal	-4	no	7.324	7.007	EPSD	ICGC;COSMIC	7.092	Loss
AGC_PKG_PRKG1_ST	Q8WZ42	TTN	Q13976	PRKG1	T13178	L13181R	13181	Missense	distal	3	no	7.324	6.890	EPSD	ICGC	7.092	Loss
AGC_PKG_PRKG1_ST	Q8WZ42	TTN	Q13976	PRKG1	T13178	G13174E	13174	Missense	distal	-4	no	7.324	7.041	EPSD	ICGC;COSMIC	7.092	Loss
AGC_PKG_PRKG1_ST	Q8WZ42	TTN	Q13976	PRKG1	T13178	R13171L	13171	Missense	distal	-7	no	7.324	5.309	EPSD	ICGC;COSMIC	7.092	Loss
AGC_PKG_PRKG1_ST	Q8WZ42	TTN	Q13976	PRKG1	T13178	V13176L	13176	Missense	proximal	-2	no	7.324	5.988	EPSD	ICGC;COSMIC	7.092	Loss
AGC_PKG_PRKG1_ST	Q8WZ42	TTN	Q13976	PRKG1	T13178	D13183N	13183	Missense	distal	5	no	7.324	7.359	EPSD	ICGC	7.092	Up-regulation
AGC_PKG_PRKG1_ST	Q8WZ42	TTN	Q13976	PRKG1	T13178	S13172L	13172	Missense	distal	-6	no	7.324	6.697	EPSD	ICGC;COSMIC	7.092	Loss
AGC_PKG_PRKG1_ST	Q8WZ42	TTN	Q13976	PRKG1	T13178	G13174R	13174	Missense	distal	-4	no	7.324	8.007	EPSD	ICGC;COSMIC	7.092	Up-regulation
AGC_PKG_PRKG1_ST	Q8WZ42	TTN	Q13976	PRKG1	T13178	T13178A	13178	Missense	central	0	yes	7.324	0.000	EPSD	ICGC;COSMIC	7.092	Loss
AGC_PKG_PRKG1_ST	Q8WZ42	TTN	Q13976	PRKG1	T13178	R13171H	13171	Missense	distal	-7	no	7.324	6.150	EPSD	ICGC;COSMIC	7.092	Loss
AGC_PKG_PRKG1_ST	Q8WZ42	TTN	Q13976	PRKG1	S13380	T13379N	13379	Missense	proximal	-1	no	8.750	8.668	EPSD	ICGC;COSMIC	7.092	Down-regulation
AGC_PKG_PRKG1_ST	Q8WZ42	TTN	Q13976	PRKG1	S13380	R13375G	13375	Missense	distal	-5	no	8.750	8.977	EPSD	ICGC;COSMIC	7.092	Up-regulation
AGC_PKG_PRKG1_ST	Q8WZ42	TTN	Q13976	PRKG1	S13380	E13373K	13373	Missense	distal	-7	no	8.750	9.752	EPSD	ICGC	7.092	Up-regulation
AGC_PKG_PRKG1_ST	Q8WZ42	TTN	Q13976	PRKG1	S13380	R13375K	13375	Missense	distal	-5	no	8.750	8.844	EPSD	ICGC;COSMIC	7.092	Up-regulation
AGC_PKG_PRKG1_ST	Q8WZ42	TTN	Q13976	PRKG1	S13380	S13380Y	13380	Missense	central	0	yes	8.750	0.000	EPSD	ICGC	7.092	Loss
AGC_PKG_PRKG1_ST	Q8WZ42	TTN	Q13976	PRKG1	S14233	Q14230K	14230	Missense	distal	-3	no	6.872	8.349	EPSD	ICGC;COSMIC	7.092	Gain
AGC_PKG_PRKG1_ST	Q8WZ42	TTN	Q13976	PRKG1	S14374	E14378K	14378	Missense	distal	4	no	8.063	7.947	EPSD	ICGC;COSMIC	7.092	Down-regulation
AGC_PKG_PRKG1_ST	Q8WZ42	TTN	Q13976	PRKG1	S14374	I14381M	14381	Missense	distal	7	no	8.063	8.193	EPSD	ICGC	7.092	Up-regulation
AGC_PKG_PRKG1_ST	Q8WZ42	TTN	Q13976	PRKG1	T14402	S14404T	14404	Missense	proximal	2	no	7.281	7.250	EPSD	ICGC;COSMIC	7.092	Down-regulation
AGC_PKG_PRKG1_ST	Q8WZ42	TTN	Q13976	PRKG1	T14402	E14406K	14406	Missense	distal	4	no	7.281	7.166	EPSD	ICGC;COSMIC	7.092	Down-regulation
AGC_PKG_PRKG1_ST	Q8WZ42	TTN	Q13976	PRKG1	S14457	R14454P	14454	Missense	distal	-3	no	7.907	3.006	EPSD	ICGC;COSMIC	7.092	Loss
AGC_PKG_PRKG1_ST	Q8WZ42	TTN	Q13976	PRKG1	S14457	R14454Q	14454	Missense	distal	-3	no	7.907	4.073	EPSD	ICGC;COSMIC	7.092	Loss
AGC_PKG_PRKG1_ST	Q8WZ42	TTN	Q13976	PRKG1	S14457	K14463T	14463	Missense	distal	6	no	7.907	7.959	EPSD	ICGC;COSMIC	7.092	Up-regulation
AGC_PKG_PRKG1_ST	Q8WZ42	TTN	Q13976	PRKG1	S14457	V14450I	14450	Missense	distal	-7	no	7.907	7.390	EPSD	ICGC;COSMIC	7.092	Down-regulation
AGC_PKG_PRKG1_ST	Q8WZ42	TTN	Q13976	PRKG1	S14457	E14455D	14455	Missense	proximal	-2	no	7.907	7.004	EPSD	ICGC;COSMIC;CCLE	7.092	Loss
AGC_PKG_PRKG1_ST	Q8WZ42	TTN	Q13976	PRKG1	S14558	E14552K	14552	Missense	distal	-6	no	8.757	9.237	EPSD	ICGC;COSMIC	7.092	Up-regulation
AGC_PKG_PRKG1_ST	Q8WZ42	TTN	Q13976	PRKG1	S14558	R14556H	14556	Missense	proximal	-2	no	8.757	4.499	EPSD	ICGC;COSMIC	7.092	Loss
AGC_PKG_PRKG1_ST	Q8WZ42	TTN	Q13976	PRKG1	S14558	K14560E	14560	Missense	proximal	2	no	8.757	8.706	EPSD	ICGC;COSMIC	7.092	Down-regulation
AGC_PKG_PRKG1_ST	Q8WZ42	TTN	Q13976	PRKG1	S14558	C14554Y	14554	Missense	distal	-4	no	8.757	8.808	EPSD	ICGC;COSMIC	7.092	Up-regulation
AGC_PKG_PRKG1_ST	Q8WZ42	TTN	Q13976	PRKG1	S14558	S14558F	14558	Missense	central	0	yes	8.757	0.000	EPSD	ICGC	7.092	Loss
AGC_PKG_PRKG1_ST	Q8WZ42	TTN	Q13976	PRKG1	S14558	P14555L	14555	Missense	distal	-3	no	8.757	6.514	EPSD	ICGC;COSMIC	7.092	Loss
AGC_PKG_PRKG1_ST	Q8WZ42	TTN	Q13976	PRKG1	S14558	R14553G	14553	Missense	distal	-5	no	8.757	8.984	EPSD	ICGC;COSMIC	7.092	Up-regulation
AGC_PKG_PRKG1_ST	Q8WZ42	TTN	Q13976	PRKG1	S14558	R14556C	14556	Missense	proximal	-2	no	8.757	4.028	EPSD	ICGC;COSMIC	7.092	Loss
AGC_PKG_PRKG1_ST	Q8WZ42	TTN	Q13976	PRKG1	S14558	D14559G	14559	Missense	proximal	1	no	8.757	8.902	EPSD	ICGC;COSMIC	7.092	Up-regulation
AGC_PKG_PRKG1_ST	Q8WZ42	TTN	Q13976	PRKG1	T14674	V14675A	14675	Missense	proximal	1	no	6.943	7.266	EPSD	ICGC;COSMIC	7.092	Gain
AGC_PKG_PRKG1_ST	Q8WZ42	TTN	Q13976	PRKG1	T14674	P14670S	14670	Missense	distal	-4	no	6.943	7.366	EPSD	ICGC	7.092	Gain
AGC_PKG_PRKG1_ST	Q8WZ42	TTN	Q13976	PRKG1	T14752	K14759N	14759	Missense	distal	7	no	10.107	10.051	EPSD	ICGC;COSMIC	7.092	Down-regulation
AGC_PKG_PRKG1_ST	Q8WZ42	TTN	Q13976	PRKG1	T14752	V14746F	14746	Missense	distal	-6	no	10.107	10.190	EPSD	ICGC;COSMIC	7.092	Up-regulation
AGC_PKG_PRKG1_ST	Q8WZ42	TTN	Q13976	PRKG1	T14752	E14755K	14755	Missense	distal	3	no	10.107	9.933	EPSD	ICGC	7.092	Down-regulation
AGC_PKG_PRKG1_ST	Q8WZ42	TTN	Q13976	PRKG1	T14752	D14753H	14753	Missense	proximal	1	no	10.107	10.280	EPSD	ICGC;COSMIC	7.092	Up-regulation
AGC_PKG_PRKG1_ST	Q8WZ42	TTN	Q13976	PRKG1	T14752	K14759T	14759	Missense	distal	7	no	10.107	10.099	EPSD	ICGC	7.092	Down-regulation
AGC_PKG_PRKG1_ST	Q8WZ42	TTN	Q13976	PRKG1	S14754	E14755K	14755	Missense	proximal	1	no	6.926	7.232	EPSD	ICGC	7.092	Gain
AGC_PKG_PRKG1_ST	Q8WZ42	TTN	Q13976	PRKG1	S14926	V14927G	14927	Missense	proximal	1	no	6.949	7.095	EPSD	ICGC;COSMIC	7.092	Gain
AGC_PKG_PRKG1_ST	Q8WZ42	TTN	Q13976	PRKG1	T14966	G14963R	14963	Missense	distal	-3	no	2.955	7.545	EPSD	ICGC;COSMIC	7.092	Gain
AGC_PKG_PRKG1_ST	Q8WZ42	TTN	Q13976	PRKG1	S15263	E15256K	15256	Missense	distal	-7	no	9.330	10.332	EPSD	ICGC;COSMIC	7.092	Up-regulation
AGC_PKG_PRKG1_ST	Q8WZ42	TTN	Q13976	PRKG1	T15452	R15445C	15445	Missense	distal	-7	no	8.948	7.520	EPSD	ICGC;COSMIC	7.092	Down-regulation
AGC_PKG_PRKG1_ST	Q8WZ42	TTN	Q13976	PRKG1	T15452	M15457I	15457	Missense	distal	5	no	8.948	8.854	EPSD	ICGC;COSMIC	7.092	Down-regulation
AGC_PKG_PRKG1_ST	Q8WZ42	TTN	Q13976	PRKG1	T15452	P15455Q	15455	Missense	distal	3	no	8.948	8.704	EPSD	ICGC;COSMIC	7.092	Down-regulation
AGC_PKG_PRKG1_ST	Q8WZ42	TTN	Q13976	PRKG1	T15452	S15458A	15458	Missense	distal	6	no	8.948	8.980	EPSD	ICGC;COSMIC	7.092	Up-regulation
AGC_PKG_PRKG1_ST	Q8WZ42	TTN	Q13976	PRKG1	T15452	M15457V	15457	Missense	distal	5	no	8.948	8.890	EPSD	ICGC	7.092	Down-regulation
AGC_PKG_PRKG1_ST	Q8WZ42	TTN	Q13976	PRKG1	S15615	P15608T	15608	Missense	distal	-7	no	6.602	7.156	EPSD	ICGC;COSMIC	7.092	Gain
AGC_PKG_PRKG1_ST	Q8WZ42	TTN	Q13976	PRKG1	S15615	I15611T	15611	Missense	distal	-4	no	6.602	7.323	EPSD	ICGC;COSMIC	7.092	Gain
AGC_PKG_PRKG1_ST	Q8WZ42	TTN	Q13976	PRKG1	S15682	N15685K	15685	Missense	distal	3	no	8.818	8.718	EPSD	ICGC;COSMIC	7.092	Down-regulation
AGC_PKG_PRKG1_ST	Q8WZ42	TTN	Q13976	PRKG1	S15682	P15676T	15676	Missense	distal	-6	no	8.818	9.050	EPSD	ICGC	7.092	Up-regulation
AGC_PKG_PRKG1_ST	Q8WZ42	TTN	Q13976	PRKG1	S15682	P15676H	15676	Missense	distal	-6	no	8.818	8.905	EPSD	ICGC;COSMIC	7.092	Up-regulation
AGC_PKG_PRKG1_ST	Q8WZ42	TTN	Q13976	PRKG1	S15682	G15689R	15689	Missense	distal	7	no	8.818	8.930	EPSD	ICGC;COSMIC	7.092	Up-regulation
AGC_PKG_PRKG1_ST	Q8WZ42	TTN	Q13976	PRKG1	S15682	I15683T	15683	Missense	proximal	1	no	8.818	9.232	EPSD	ICGC;COSMIC	7.092	Up-regulation
AGC_PKG_PRKG1_ST	Q8WZ42	TTN	Q13976	PRKG1	S15691	G15689R	15689	Missense	proximal	-2	no	6.549	10.037	EPSD	ICGC;COSMIC	7.092	Gain
AGC_PKG_PRKG1_ST	Q8WZ42	TTN	Q13976	PRKG1	S15744	S15744P	15744	Missense	central	0	yes	10.204	0.000	EPSD	ICGC;COSMIC	7.092	Loss
AGC_PKG_PRKG1_ST	Q8WZ42	TTN	Q13976	PRKG1	S15744	K15742N	15742	Missense	proximal	-2	no	10.204	7.260	EPSD	ICGC;COSMIC	7.092	Down-regulation
AGC_PKG_PRKG1_ST	Q8WZ42	TTN	Q13976	PRKG1	S15744	D15739Y	15739	Missense	distal	-5	no	10.204	10.143	EPSD	ICGC;COSMIC	7.092	Down-regulation
AGC_PKG_PRKG1_ST	Q8WZ42	TTN	Q13976	PRKG1	S15744	T15743A	15743	Missense	proximal	-1	no	10.204	10.199	EPSD	ICGC;COSMIC	7.092	Down-regulation
AGC_PKG_PRKG1_ST	Q8WZ42	TTN	Q13976	PRKG1	S15744	L15746I	15746	Missense	proximal	2	no	10.204	10.219	EPSD	ICGC;COSMIC	7.092	Up-regulation
AGC_PKG_PRKG1_ST	Q8WZ42	TTN	Q13976	PRKG1	S15876	H15874R	15874	Missense	proximal	-2	no	4.598	8.856	EPSD	ICGC	7.092	Gain
AGC_PKG_PRKG1_ST	Q8WZ42	TTN	Q13976	PRKG1	T15989	V15990I	15990	Missense	proximal	1	no	7.699	7.569	EPSD	ICGC;COSMIC	7.092	Down-regulation
AGC_PKG_PRKG1_ST	Q8WZ42	TTN	Q13976	PRKG1	T15989	R15986L	15986	Missense	distal	-3	no	7.699	0.554	EPSD	ICGC;COSMIC	7.092	Loss
AGC_PKG_PRKG1_ST	Q8WZ42	TTN	Q13976	PRKG1	T15989	T15989I	15989	Missense	central	0	yes	7.699	0.000	EPSD	ICGC;COSMIC	7.092	Loss
AGC_PKG_PRKG1_ST	Q8WZ42	TTN	Q13976	PRKG1	S16111	S16108R	16108	Missense	distal	-3	no	4.391	9.880	EPSD	ICGC	7.092	Gain
AGC_PKG_PRKG1_ST	Q8WZ42	TTN	Q13976	PRKG1	S16236	R16233W	16233	Missense	distal	-3	no	10.991	3.318	EPSD	ICGC	7.092	Loss
AGC_PKG_PRKG1_ST	Q8WZ42	TTN	Q13976	PRKG1	S16236	T16229K	16229	Missense	distal	-7	no	10.991	11.370	EPSD	ICGC;COSMIC	7.092	Up-regulation
AGC_PKG_PRKG1_ST	Q8WZ42	TTN	Q13976	PRKG1	S16236	L16240I	16240	Missense	distal	4	no	10.991	10.961	EPSD	ICGC	7.092	Down-regulation
AGC_PKG_PRKG1_ST	Q8WZ42	TTN	Q13976	PRKG1	S16329	R16331Q	16331	Missense	proximal	2	no	7.660	7.653	EPSD	ICGC;COSMIC	7.092	Down-regulation
AGC_PKG_PRKG1_ST	Q8WZ42	TTN	Q13976	PRKG1	S16329	R16327C	16327	Missense	proximal	-2	no	7.660	2.931	EPSD	ICGC;COSMIC	7.092	Loss
AGC_PKG_PRKG1_ST	Q8WZ42	TTN	Q13976	PRKG1	S16329	S16329R	16329	Missense	central	0	yes	7.660	0.000	EPSD	ICGC;COSMIC	7.092	Loss
AGC_PKG_PRKG1_ST	Q8WZ42	TTN	Q13976	PRKG1	S16329	R16331L	16331	Missense	proximal	2	no	7.660	7.529	EPSD	ICGC;COSMIC	7.092	Down-regulation
AGC_PKG_PRKG1_ST	Q8WZ42	TTN	Q13976	PRKG1	S16329	T16323S	16323	Missense	distal	-6	no	7.660	7.743	EPSD	ICGC;COSMIC	7.092	Up-regulation
AGC_PKG_PRKG1_ST	Q8WZ42	TTN	Q13976	PRKG1	S16329	R16327H	16327	Missense	proximal	-2	no	7.660	3.402	EPSD	ICGC;COSMIC	7.092	Loss
AGC_PKG_PRKG1_ST	Q8WZ42	TTN	Q13976	PRKG1	S16329	P16322S	16322	Missense	distal	-7	no	7.660	8.427	EPSD	ICGC;COSMIC	7.092	Up-regulation
AGC_PKG_PRKG1_ST	Q8WZ42	TTN	Q13976	PRKG1	S16329	G16332E	16332	Missense	distal	3	no	7.660	7.687	EPSD	ICGC;COSMIC	7.092	Up-regulation
AGC_PKG_PRKG1_ST	Q8WZ42	TTN	Q13976	PRKG1	S16329	P16322Q	16322	Missense	distal	-7	no	7.660	8.383	EPSD	ICGC;COSMIC	7.092	Up-regulation
AGC_PKG_PRKG1_ST	Q8WZ42	TTN	Q13976	PRKG1	T16334	R16331Q	16331	Missense	distal	-3	no	7.497	3.662	EPSD	ICGC;COSMIC	7.092	Loss
AGC_PKG_PRKG1_ST	Q8WZ42	TTN	Q13976	PRKG1	T16334	R16327C	16327	Missense	distal	-7	no	7.497	6.069	EPSD	ICGC;COSMIC	7.092	Loss
AGC_PKG_PRKG1_ST	Q8WZ42	TTN	Q13976	PRKG1	T16334	S16329R	16329	Missense	distal	-5	no	7.497	7.356	EPSD	ICGC;COSMIC	7.092	Down-regulation
AGC_PKG_PRKG1_ST	Q8WZ42	TTN	Q13976	PRKG1	T16334	A16339E	16339	Missense	distal	5	no	7.497	7.453	EPSD	ICGC;COSMIC	7.092	Down-regulation
AGC_PKG_PRKG1_ST	Q8WZ42	TTN	Q13976	PRKG1	T16334	R16331L	16331	Missense	distal	-3	no	7.497	0.353	EPSD	ICGC;COSMIC	7.092	Loss
AGC_PKG_PRKG1_ST	Q8WZ42	TTN	Q13976	PRKG1	T16334	A16339V	16339	Missense	distal	5	no	7.497	7.447	EPSD	ICGC	7.092	Down-regulation
AGC_PKG_PRKG1_ST	Q8WZ42	TTN	Q13976	PRKG1	T16334	R16327H	16327	Missense	distal	-7	no	7.497	6.324	EPSD	ICGC;COSMIC	7.092	Loss
AGC_PKG_PRKG1_ST	Q8WZ42	TTN	Q13976	PRKG1	T16334	G16332E	16332	Missense	proximal	-2	no	7.497	5.985	EPSD	ICGC;COSMIC	7.092	Loss
AGC_PKG_PRKG1_ST	Q8WZ42	TTN	Q13976	PRKG1	T16334	K16338N	16338	Missense	distal	4	no	7.497	7.573	EPSD	ICGC;COSMIC	7.092	Up-regulation
AGC_PKG_PRKG1_ST	Q8WZ42	TTN	Q13976	PRKG1	S16509	G16507R	16507	Missense	proximal	-2	no	5.064	8.552	EPSD	ICGC;COSMIC	7.092	Gain
AGC_PKG_PRKG1_ST	Q8WZ42	TTN	Q13976	PRKG1	S16646	E16639Q	16639	Missense	distal	-7	no	7.331	8.121	EPSD	ICGC;COSMIC	7.092	Up-regulation
AGC_PKG_PRKG1_ST	Q8WZ42	TTN	Q13976	PRKG1	S16646	V16640A	16640	Missense	distal	-6	no	7.331	7.667	EPSD	ICGC;COSMIC	7.092	Up-regulation
AGC_PKG_PRKG1_ST	Q8WZ42	TTN	Q13976	PRKG1	S16646	K16645T	16645	Missense	proximal	-1	no	7.331	7.286	EPSD	ICGC;COSMIC	7.092	Down-regulation
AGC_PKG_PRKG1_ST	Q8WZ42	TTN	Q13976	PRKG1	S16646	L16650I	16650	Missense	distal	4	no	7.331	7.301	EPSD	ICGC	7.092	Down-regulation
AGC_PKG_PRKG1_ST	Q8WZ42	TTN	Q13976	PRKG1	S16646	T16644R	16644	Missense	proximal	-2	no	7.331	10.923	EPSD	ICGC;COSMIC	7.092	Up-regulation
AGC_PKG_PRKG1_ST	Q8WZ42	TTN	Q13976	PRKG1	S16646	K16653N	16653	Missense	distal	7	no	7.331	7.275	EPSD	ICGC;COSMIC	7.092	Down-regulation
AGC_PKG_PRKG1_ST	Q8WZ42	TTN	Q13976	PRKG1	S16646	I16648V	16648	Missense	proximal	2	no	7.331	7.349	EPSD	ICGC;COSMIC	7.092	Up-regulation
AGC_PKG_PRKG1_ST	Q8WZ42	TTN	Q13976	PRKG1	S16647	V16640A	16640	Missense	distal	-7	no	7.339	8.042	EPSD	ICGC;COSMIC	7.092	Up-regulation
AGC_PKG_PRKG1_ST	Q8WZ42	TTN	Q13976	PRKG1	S16647	K16645T	16645	Missense	proximal	-2	no	7.339	5.224	EPSD	ICGC;COSMIC	7.092	Loss
AGC_PKG_PRKG1_ST	Q8WZ42	TTN	Q13976	PRKG1	S16647	L16650I	16650	Missense	distal	3	no	7.339	7.291	EPSD	ICGC	7.092	Down-regulation
AGC_PKG_PRKG1_ST	Q8WZ42	TTN	Q13976	PRKG1	S16647	T16644R	16644	Missense	distal	-3	no	7.339	12.505	EPSD	ICGC;COSMIC	7.092	Up-regulation
AGC_PKG_PRKG1_ST	Q8WZ42	TTN	Q13976	PRKG1	S16647	K16653N	16653	Missense	distal	6	no	7.339	7.493	EPSD	ICGC;COSMIC	7.092	Up-regulation
AGC_PKG_PRKG1_ST	Q8WZ42	TTN	Q13976	PRKG1	S16647	I16648V	16648	Missense	proximal	1	no	7.339	7.468	EPSD	ICGC;COSMIC	7.092	Up-regulation
AGC_PKG_PRKG1_ST	Q8WZ42	TTN	Q13976	PRKG1	S16817	R16810Q	16810	Missense	distal	-7	no	9.144	8.468	EPSD	ICGC;COSMIC;CCLE	7.092	Down-regulation
AGC_PKG_PRKG1_ST	Q8WZ42	TTN	Q13976	PRKG1	S16817	K16823E	16823	Missense	distal	6	no	9.144	9.361	EPSD	ICGC;COSMIC	7.092	Up-regulation
AGC_PKG_PRKG1_ST	Q8WZ42	TTN	Q13976	PRKG1	S16817	R16810L	16810	Missense	distal	-7	no	9.144	7.129	EPSD	ICGC;COSMIC	7.092	Down-regulation
AGC_PKG_PRKG1_ST	Q8WZ42	TTN	Q13976	PRKG1	S16817	T16819A	16819	Missense	proximal	2	no	9.144	9.151	EPSD	ICGC;COSMIC	7.092	Up-regulation
AGC_PKG_PRKG1_ST	Q8WZ42	TTN	Q13976	PRKG1	S16854	V16847A	16847	Missense	distal	-7	no	8.172	8.874	EPSD	ICGC;COSMIC	7.092	Up-regulation
AGC_PKG_PRKG1_ST	Q8WZ42	TTN	Q13976	PRKG1	S16854	R16852K	16852	Missense	proximal	-2	no	8.172	6.694	EPSD	ICGC;COSMIC	7.092	Loss
AGC_PKG_PRKG1_ST	Q8WZ42	TTN	Q13976	PRKG1	T16931	P16935L	16935	Missense	distal	4	no	7.054	7.154	EPSD	ICGC;COSMIC	7.092	Gain
AGC_PKG_PRKG1_ST	Q8WZ42	TTN	Q13976	PRKG1	T16931	E16925K	16925	Missense	distal	-6	no	7.054	7.535	EPSD	ICGC;COSMIC	7.092	Gain
AGC_PKG_PRKG1_ST	Q8WZ42	TTN	Q13976	PRKG1	T17118	R17114H	17114	Missense	distal	-4	no	8.734	7.978	EPSD	ICGC	7.092	Down-regulation
AGC_PKG_PRKG1_ST	Q8WZ42	TTN	Q13976	PRKG1	T17118	R17114C	17114	Missense	distal	-4	no	8.734	7.774	EPSD	ICGC;COSMIC	7.092	Down-regulation
AGC_PKG_PRKG1_ST	Q8WZ42	TTN	Q13976	PRKG1	T17118	A17125T	17125	Missense	distal	7	no	8.734	8.744	EPSD	ICGC;COSMIC	7.092	Up-regulation
AGC_PKG_PRKG1_ST	Q8WZ42	TTN	Q13976	PRKG1	T17118	Y17121H	17121	Missense	distal	3	no	8.734	8.633	EPSD	ICGC;COSMIC	7.092	Down-regulation
AGC_PKG_PRKG1_ST	Q8WZ42	TTN	Q13976	PRKG1	T17118	R17114S	17114	Missense	distal	-4	no	8.734	8.264	EPSD	ICGC;COSMIC	7.092	Down-regulation
AGC_PKG_PRKG1_ST	Q8WZ42	TTN	Q13976	PRKG1	T17202	E17200K	17200	Missense	proximal	-2	no	4.764	8.287	EPSD	ICGC;COSMIC	7.092	Gain
AGC_PKG_PRKG1_ST	Q8WZ42	TTN	Q13976	PRKG1	T17410	L17407R	17407	Missense	distal	-3	no	1.386	8.530	EPSD	ICGC	7.092	Gain
AGC_PKG_PRKG1_ST	Q8WZ42	TTN	Q13976	PRKG1	S17448	A17455D	17455	Missense	distal	7	no	7.953	7.873	EPSD	ICGC;COSMIC	7.092	Down-regulation
AGC_PKG_PRKG1_ST	Q8WZ42	TTN	Q13976	PRKG1	S17448	R17445I	17445	Missense	distal	-3	no	7.953	-0.553	EPSD	ICGC	7.092	Loss
AGC_PKG_PRKG1_ST	Q8WZ42	TTN	Q13976	PRKG1	S17448	A17455T	17455	Missense	distal	7	no	7.953	7.964	EPSD	ICGC	7.092	Up-regulation
AGC_PKG_PRKG1_ST	Q8WZ42	TTN	Q13976	PRKG1	S17448	E17441K	17441	Missense	distal	-7	no	7.953	8.954	EPSD	ICGC;COSMIC	7.092	Up-regulation
AGC_PKG_PRKG1_ST	Q8WZ42	TTN	Q13976	PRKG1	S17521	V17519I	17519	Missense	proximal	-2	no	7.145	5.099	EPSD	ICGC;COSMIC	7.092	Loss
AGC_PKG_PRKG1_ST	Q8WZ42	TTN	Q13976	PRKG1	S17521	A17528T	17528	Missense	distal	7	no	7.145	7.156	EPSD	ICGC;COSMIC	7.092	Up-regulation
AGC_PKG_PRKG1_ST	Q8WZ42	TTN	Q13976	PRKG1	S17521	S17515N	17515	Missense	distal	-6	no	7.145	6.864	EPSD	ICGC	7.092	Loss
AGC_PKG_PRKG1_ST	Q8WZ42	TTN	Q13976	PRKG1	S17521	S17521Y	17521	Missense	central	0	yes	7.145	0.000	EPSD	ICGC;COSMIC	7.092	Loss
AGC_PKG_PRKG1_ST	Q8WZ42	TTN	Q13976	PRKG1	S17521	L17523I	17523	Missense	proximal	2	no	7.145	7.161	EPSD	ICGC;COSMIC	7.092	Up-regulation
AGC_PKG_PRKG1_ST	Q8WZ42	TTN	Q13976	PRKG1	S17521	L17522I	17522	Missense	proximal	1	no	7.145	7.173	EPSD	ICGC;COSMIC	7.092	Up-regulation
AGC_PKG_PRKG1_ST	Q8WZ42	TTN	Q13976	PRKG1	S17521	E17527K	17527	Missense	distal	6	no	7.145	6.928	EPSD	ICGC	7.092	Loss
AGC_PKG_PRKG1_ST	Q8WZ42	TTN	Q13976	PRKG1	S17521	N17526H	17526	Missense	distal	5	no	7.145	7.152	EPSD	ICGC;COSMIC	7.092	Up-regulation
AGC_PKG_PRKG1_ST	Q8WZ42	TTN	Q13976	PRKG1	S17521	G17518D	17518	Missense	distal	-3	no	7.145	3.248	EPSD	ICGC;COSMIC	7.092	Loss
AGC_PKG_PRKG1_ST	Q8WZ42	TTN	Q13976	PRKG1	T17591	P17592T	17592	Missense	proximal	1	no	8.843	9.055	EPSD	ICGC;COSMIC	7.092	Up-regulation
AGC_PKG_PRKG1_ST	Q8WZ42	TTN	Q13976	PRKG1	T17591	V17593M	17593	Missense	proximal	2	no	8.843	8.911	EPSD	ICGC;COSMIC	7.092	Up-regulation
AGC_PKG_PRKG1_ST	Q8WZ42	TTN	Q13976	PRKG1	T17591	R17587S	17587	Missense	distal	-4	no	8.843	8.374	EPSD	ICGC;COSMIC	7.092	Down-regulation
AGC_PKG_PRKG1_ST	Q8WZ42	TTN	Q13976	PRKG1	T17591	D17586E	17586	Missense	distal	-5	no	8.843	8.802	EPSD	ICGC	7.092	Down-regulation
AGC_PKG_PRKG1_ST	Q8WZ42	TTN	Q13976	PRKG1	T17591	T17594K	17594	Missense	distal	3	no	8.843	8.867	EPSD	ICGC	7.092	Up-regulation
AGC_PKG_PRKG1_ST	Q8WZ42	TTN	Q13976	PRKG1	T17591	R17588K	17588	Missense	distal	-3	no	8.843	6.485	EPSD	ICGC;COSMIC	7.092	Loss
AGC_PKG_PRKG1_ST	Q8WZ42	TTN	Q13976	PRKG1	T17591	W17590C	17590	Missense	proximal	-1	no	8.843	8.899	EPSD	ICGC;COSMIC;CCLE	7.092	Up-regulation
AGC_PKG_PRKG1_ST	Q8WZ42	TTN	Q13976	PRKG1	S17770	G17767S	17767	Missense	distal	-3	no	9.348	8.450	EPSD	ICGC;COSMIC	7.092	Down-regulation
AGC_PKG_PRKG1_ST	Q8WZ42	TTN	Q13976	PRKG1	S17770	T17766N	17766	Missense	distal	-4	no	9.348	9.094	EPSD	ICGC;COSMIC	7.092	Down-regulation
AGC_PKG_PRKG1_ST	Q8WZ42	TTN	Q13976	PRKG1	S17778	D17785Y	17785	Missense	distal	7	no	7.633	7.652	EPSD	ICGC;COSMIC	7.092	Up-regulation
AGC_PKG_PRKG1_ST	Q8WZ42	TTN	Q13976	PRKG1	S17778	K17781E	17781	Missense	distal	3	no	7.633	7.807	EPSD	ICGC;COSMIC	7.092	Up-regulation
AGC_PKG_PRKG1_ST	Q8WZ42	TTN	Q13976	PRKG1	T17970	P17968R	17968	Missense	proximal	-2	no	3.503	7.262	EPSD	ICGC;COSMIC	7.092	Gain
AGC_PKG_PRKG1_ST	Q8WZ42	TTN	Q13976	PRKG1	T17979	R17983L	17983	Missense	distal	4	no	7.685	7.972	EPSD	ICGC;COSMIC	7.092	Up-regulation
AGC_PKG_PRKG1_ST	Q8WZ42	TTN	Q13976	PRKG1	T17979	I17973M	17973	Missense	distal	-6	no	7.685	8.205	EPSD	ICGC;COSMIC	7.092	Up-regulation
AGC_PKG_PRKG1_ST	Q8WZ42	TTN	Q13976	PRKG1	T17979	L17974M	17974	Missense	distal	-5	no	7.685	7.469	EPSD	ICGC;COSMIC	7.092	Down-regulation
AGC_PKG_PRKG1_ST	Q8WZ42	TTN	Q13976	PRKG1	T17979	K17976N	17976	Missense	distal	-3	no	7.685	3.138	EPSD	ICGC;COSMIC	7.092	Loss
AGC_PKG_PRKG1_ST	Q8WZ42	TTN	Q13976	PRKG1	T17979	S17981F	17981	Missense	proximal	2	no	7.685	7.608	EPSD	ICGC	7.092	Down-regulation
AGC_PKG_PRKG1_ST	Q8WZ42	TTN	Q13976	PRKG1	T17979	S17981P	17981	Missense	proximal	2	no	7.685	7.586	EPSD	ICGC;COSMIC	7.092	Down-regulation
AGC_PKG_PRKG1_ST	Q8WZ42	TTN	Q13976	PRKG1	T17988	R17983L	17983	Missense	distal	-5	no	7.822	8.199	EPSD	ICGC;COSMIC	7.092	Up-regulation
AGC_PKG_PRKG1_ST	Q8WZ42	TTN	Q13976	PRKG1	T17988	Y17995C	17995	Missense	distal	7	no	7.822	7.833	EPSD	ICGC;COSMIC	7.092	Up-regulation
AGC_PKG_PRKG1_ST	Q8WZ42	TTN	Q13976	PRKG1	T17988	H17993N	17993	Missense	distal	5	no	7.822	7.815	EPSD	ICGC	7.092	Down-regulation
AGC_PKG_PRKG1_ST	Q8WZ42	TTN	Q13976	PRKG1	T17988	P17994A	17994	Missense	distal	6	no	7.822	7.618	EPSD	ICGC;COSMIC	7.092	Down-regulation
AGC_PKG_PRKG1_ST	Q8WZ42	TTN	Q13976	PRKG1	T17988	V17987G	17987	Missense	proximal	-1	no	7.822	7.873	EPSD	ICGC;COSMIC	7.092	Up-regulation
AGC_PKG_PRKG1_ST	Q8WZ42	TTN	Q13976	PRKG1	T17988	S17981F	17981	Missense	distal	-7	no	7.822	7.177	EPSD	ICGC	7.092	Down-regulation
AGC_PKG_PRKG1_ST	Q8WZ42	TTN	Q13976	PRKG1	T17988	S17981P	17981	Missense	distal	-7	no	7.822	7.055	EPSD	ICGC;COSMIC	7.092	Loss
AGC_PKG_PRKG1_ST	Q8WZ42	TTN	Q13976	PRKG1	S18014	E18010K	18010	Missense	distal	-4	no	6.734	7.394	EPSD	ICGC;COSMIC	7.092	Gain
AGC_PKG_PRKG1_ST	Q8WZ42	TTN	Q13976	PRKG1	S18166	V18159I	18159	Missense	distal	-7	no	8.502	7.985	EPSD	ICGC;COSMIC	7.092	Down-regulation
AGC_PKG_PRKG1_ST	Q8WZ42	TTN	Q13976	PRKG1	S18166	P18173Q	18173	Missense	distal	7	no	8.502	8.600	EPSD	ICGC;COSMIC	7.092	Up-regulation
AGC_PKG_PRKG1_ST	Q8WZ42	TTN	Q13976	PRKG1	S18166	P18173T	18173	Missense	distal	7	no	8.502	8.592	EPSD	ICGC;COSMIC	7.092	Up-regulation
AGC_PKG_PRKG1_ST	Q8WZ42	TTN	Q13976	PRKG1	S18166	P18173S	18173	Missense	distal	7	no	8.502	8.604	EPSD	ICGC;COSMIC	7.092	Up-regulation
AGC_PKG_PRKG1_ST	Q8WZ42	TTN	Q13976	PRKG1	T18505	N18499S	18499	Missense	distal	-6	no	10.443	10.724	EPSD	ICGC;COSMIC	7.092	Up-regulation
AGC_PKG_PRKG1_ST	Q8WZ42	TTN	Q13976	PRKG1	T18505	K18498T	18498	Missense	distal	-7	no	10.443	10.064	EPSD	ICGC	7.092	Down-regulation
AGC_PKG_PRKG1_ST	Q8WZ42	TTN	Q13976	PRKG1	T18505	E18507K	18507	Missense	proximal	2	no	10.443	10.494	EPSD	ICGC;COSMIC	7.092	Up-regulation
AGC_PKG_PRKG1_ST	Q8WZ42	TTN	Q13976	PRKG1	T18577	V18580G	18580	Missense	distal	3	no	10.483	10.419	EPSD	ICGC;COSMIC	7.092	Down-regulation
AGC_PKG_PRKG1_ST	Q8WZ42	TTN	Q13976	PRKG1	T18577	D18576E	18576	Missense	proximal	-1	no	10.483	10.526	EPSD	ICGC;COSMIC	7.092	Up-regulation
AGC_PKG_PRKG1_ST	Q8WZ42	TTN	Q13976	PRKG1	S18920	V18923I	18923	Missense	distal	3	no	7.021	7.115	EPSD	ICGC;COSMIC	7.092	Gain
AGC_PKG_PRKG1_ST	Q8WZ42	TTN	Q13976	PRKG1	S18920	Q18918R	18918	Missense	proximal	-2	no	7.021	9.986	EPSD	ICGC;COSMIC	7.092	Gain
AGC_PKG_PRKG1_ST	Q8WZ42	TTN	Q13976	PRKG1	S18976	Q18972L	18972	Missense	distal	-4	no	7.647	6.799	EPSD	ICGC;COSMIC	7.092	Loss
AGC_PKG_PRKG1_ST	Q8WZ42	TTN	Q13976	PRKG1	S18976	V18978F	18978	Missense	proximal	2	no	7.647	7.679	EPSD	ICGC;COSMIC	7.092	Up-regulation
AGC_PKG_PRKG1_ST	Q8WZ42	TTN	Q13976	PRKG1	T19042	G19040R	19040	Missense	proximal	-2	no	4.954	8.442	EPSD	ICGC;COSMIC	7.092	Gain
AGC_PKG_PRKG1_ST	Q8WZ42	TTN	Q13976	PRKG1	S19081	H19078R	19078	Missense	distal	-3	no	5.904	11.971	EPSD	ICGC;COSMIC	7.092	Gain
AGC_PKG_PRKG1_ST	Q8WZ42	TTN	Q13976	PRKG1	S19189	R19182H	19182	Missense	distal	-7	no	8.058	6.885	EPSD	ICGC;COSMIC	7.092	Loss
AGC_PKG_PRKG1_ST	Q8WZ42	TTN	Q13976	PRKG1	S19189	S19189Y	19189	Missense	central	0	yes	8.058	0.000	EPSD	ICGC;COSMIC	7.092	Loss
AGC_PKG_PRKG1_ST	Q8WZ42	TTN	Q13976	PRKG1	S19189	S19186Y	19186	Missense	distal	-3	no	8.058	7.693	EPSD	ICGC;COSMIC	7.092	Down-regulation
AGC_PKG_PRKG1_ST	Q8WZ42	TTN	Q13976	PRKG1	S19189	F19188I	19188	Missense	proximal	-1	no	8.058	7.951	EPSD	ICGC;COSMIC	7.092	Down-regulation
AGC_PKG_PRKG1_ST	Q8WZ42	TTN	Q13976	PRKG1	S19189	R19195Q	19195	Missense	distal	6	no	8.058	8.129	EPSD	ICGC;COSMIC	7.092	Up-regulation
AGC_PKG_PRKG1_ST	Q8WZ42	TTN	Q13976	PRKG1	S19366	E19363K	19363	Missense	distal	-3	no	4.632	9.215	EPSD	ICGC;COSMIC	7.092	Gain
AGC_PKG_PRKG1_ST	Q8WZ42	TTN	Q13976	PRKG1	S19375	V19372A	19372	Missense	distal	-3	no	6.062	7.164	EPSD	ICGC;COSMIC	7.092	Gain
AGC_PKG_PRKG1_ST	Q8WZ42	TTN	Q13976	PRKG1	S19604	R19597C	19597	Missense	distal	-7	no	8.903	7.476	EPSD	ICGC;COSMIC	7.092	Down-regulation
AGC_PKG_PRKG1_ST	Q8WZ42	TTN	Q13976	PRKG1	S19604	L19607I	19607	Missense	distal	3	no	8.903	8.855	EPSD	ICGC	7.092	Down-regulation
AGC_PKG_PRKG1_ST	Q8WZ42	TTN	Q13976	PRKG1	S19604	T19606K	19606	Missense	proximal	2	no	8.903	8.908	EPSD	ICGC	7.092	Up-regulation
AGC_PKG_PRKG1_ST	Q8WZ42	TTN	Q13976	PRKG1	S19604	N19609K	19609	Missense	distal	5	no	8.903	8.940	EPSD	ICGC;COSMIC	7.092	Up-regulation
AGC_PKG_PRKG1_ST	Q8WZ42	TTN	Q13976	PRKG1	S19604	D19598N	19598	Missense	distal	-6	no	8.903	9.114	EPSD	ICGC;COSMIC	7.092	Up-regulation
AGC_PKG_PRKG1_ST	Q8WZ42	TTN	Q13976	PRKG1	S19604	G19601E	19601	Missense	distal	-3	no	8.903	6.553	EPSD	ICGC;COSMIC	7.092	Loss
AGC_PKG_PRKG1_ST	Q8WZ42	TTN	Q13976	PRKG1	S19673	K19670N	19670	Missense	distal	-3	no	8.573	4.027	EPSD	ICGC;COSMIC	7.092	Loss
AGC_PKG_PRKG1_ST	Q8WZ42	TTN	Q13976	PRKG1	S19673	E19666K	19666	Missense	distal	-7	no	8.573	9.574	EPSD	ICGC;COSMIC	7.092	Up-regulation
AGC_PKG_PRKG1_ST	Q8WZ42	TTN	Q13976	PRKG1	S19673	P19677L	19677	Missense	distal	4	no	8.573	8.673	EPSD	ICGC;COSMIC	7.092	Up-regulation
AGC_PKG_PRKG1_ST	Q8WZ42	TTN	Q13976	PRKG1	S19673	V19679I	19679	Missense	distal	6	no	8.573	8.677	EPSD	ICGC;COSMIC	7.092	Up-regulation
AGC_PKG_PRKG1_ST	Q8WZ42	TTN	Q13976	PRKG1	S19673	K19680T	19680	Missense	distal	7	no	8.573	8.565	EPSD	ICGC;COSMIC	7.092	Down-regulation
AGC_PKG_PRKG1_ST	Q8WZ42	TTN	Q13976	PRKG1	S19673	V19675A	19675	Missense	proximal	2	no	8.573	8.658	EPSD	ICGC;COSMIC	7.092	Up-regulation
AGC_PKG_PRKG1_ST	Q8WZ42	TTN	Q13976	PRKG1	S19673	P19677T	19677	Missense	distal	4	no	8.573	8.445	EPSD	ICGC;COSMIC	7.092	Down-regulation
AGC_PKG_PRKG1_ST	Q8WZ42	TTN	Q13976	PRKG1	S19673	E19678K	19678	Missense	distal	5	no	8.573	8.636	EPSD	ICGC;COSMIC	7.092	Up-regulation
AGC_PKG_PRKG1_ST	Q8WZ42	TTN	Q13976	PRKG1	S19673	V19675I	19675	Missense	proximal	2	no	8.573	8.555	EPSD	ICGC;COSMIC	7.092	Down-regulation
AGC_PKG_PRKG1_ST	Q8WZ42	TTN	Q13976	PRKG1	S19673	T19674I	19674	Missense	proximal	1	no	8.573	8.159	EPSD	ICGC	7.092	Down-regulation
AGC_PKG_PRKG1_ST	Q8WZ42	TTN	Q13976	PRKG1	S19673	A19667V	19667	Missense	distal	-6	no	8.573	8.237	EPSD	ICGC;COSMIC	7.092	Down-regulation
AGC_PKG_PRKG1_ST	Q8WZ42	TTN	Q13976	PRKG1	S19673	S19673L	19673	Missense	central	0	yes	8.573	0.000	EPSD	ICGC	7.092	Loss
AGC_PKG_PRKG1_ST	Q8WZ42	TTN	Q13976	PRKG1	S19683	P19677L	19677	Missense	distal	-6	no	9.216	8.905	EPSD	ICGC;COSMIC	7.092	Down-regulation
AGC_PKG_PRKG1_ST	Q8WZ42	TTN	Q13976	PRKG1	S19683	V19679I	19679	Missense	distal	-4	no	9.216	8.907	EPSD	ICGC;COSMIC	7.092	Down-regulation
AGC_PKG_PRKG1_ST	Q8WZ42	TTN	Q13976	PRKG1	S19683	K19680T	19680	Missense	distal	-3	no	9.216	6.408	EPSD	ICGC;COSMIC	7.092	Loss
AGC_PKG_PRKG1_ST	Q8WZ42	TTN	Q13976	PRKG1	S19683	T19687P	19687	Missense	distal	4	no	9.216	9.343	EPSD	ICGC;COSMIC	7.092	Up-regulation
AGC_PKG_PRKG1_ST	Q8WZ42	TTN	Q13976	PRKG1	S19683	T19682I	19682	Missense	proximal	-1	no	9.216	9.016	EPSD	ICGC;COSMIC	7.092	Down-regulation
AGC_PKG_PRKG1_ST	Q8WZ42	TTN	Q13976	PRKG1	S19683	P19677T	19677	Missense	distal	-6	no	9.216	9.448	EPSD	ICGC;COSMIC	7.092	Up-regulation
AGC_PKG_PRKG1_ST	Q8WZ42	TTN	Q13976	PRKG1	S19683	T19687S	19687	Missense	distal	4	no	9.216	9.192	EPSD	ICGC;COSMIC	7.092	Down-regulation
AGC_PKG_PRKG1_ST	Q8WZ42	TTN	Q13976	PRKG1	S19683	E19678K	19678	Missense	distal	-5	no	9.216	9.035	EPSD	ICGC;COSMIC	7.092	Down-regulation
AGC_PKG_PRKG1_ST	Q8WZ42	TTN	Q13976	PRKG1	S19741	K19739N	19739	Missense	proximal	-2	no	8.112	5.169	EPSD	ICGC;COSMIC	7.092	Loss
AGC_PKG_PRKG1_ST	Q8WZ42	TTN	Q13976	PRKG1	S19741	N19740S	19740	Missense	proximal	-1	no	8.112	8.196	EPSD	ICGC;COSMIC	7.092	Up-regulation
AGC_PKG_PRKG1_ST	Q8WZ42	TTN	Q13976	PRKG1	S19879	L19883V	19883	Missense	distal	4	no	7.818	7.727	EPSD	ICGC;COSMIC	7.092	Down-regulation
AGC_PKG_PRKG1_ST	Q8WZ42	TTN	Q13976	PRKG1	S19879	A19873P	19873	Missense	distal	-6	no	7.818	7.546	EPSD	ICGC;COSMIC	7.092	Down-regulation
AGC_PKG_PRKG1_ST	Q8WZ42	TTN	Q13976	PRKG1	S19879	A19877E	19877	Missense	proximal	-2	no	7.818	6.274	EPSD	ICGC;COSMIC	7.092	Loss
AGC_PKG_PRKG1_ST	Q8WZ42	TTN	Q13976	PRKG1	S19879	V19874A	19874	Missense	distal	-5	no	7.818	7.693	EPSD	ICGC	7.092	Down-regulation
AGC_PKG_PRKG1_ST	Q8WZ42	TTN	Q13976	PRKG1	S19893	D19892N	19892	Missense	proximal	-1	no	12.669	12.747	EPSD	ICGC	7.092	Up-regulation
AGC_PKG_PRKG1_ST	Q8WZ42	TTN	Q13976	PRKG1	S19893	D19892Y	19892	Missense	proximal	-1	no	12.669	12.739	EPSD	ICGC	7.092	Up-regulation
AGC_PKG_PRKG1_ST	Q8WZ42	TTN	Q13976	PRKG1	S20062	E20059K	20059	Missense	distal	-3	no	3.729	8.312	EPSD	ICGC;COSMIC	7.092	Gain
AGC_PKG_PRKG1_ST	Q8WZ42	TTN	Q13976	PRKG1	T20307	S20303C	20303	Missense	distal	-4	no	8.337	7.847	EPSD	ICGC;COSMIC	7.092	Down-regulation
AGC_PKG_PRKG1_ST	Q8WZ42	TTN	Q13976	PRKG1	T20307	L20310F	20310	Missense	distal	3	no	8.337	8.151	EPSD	ICGC;COSMIC	7.092	Down-regulation
AGC_PKG_PRKG1_ST	Q8WZ42	TTN	Q13976	PRKG1	S20366	P20360T	20360	Missense	distal	-6	no	6.925	7.158	EPSD	ICGC;COSMIC	7.092	Gain
AGC_PKG_PRKG1_ST	Q8WZ42	TTN	Q13976	PRKG1	S20501	P20500R	20500	Missense	proximal	-1	no	7.267	7.472	EPSD	ICGC;COSMIC	7.092	Up-regulation
AGC_PKG_PRKG1_ST	Q8WZ42	TTN	Q13976	PRKG1	S20501	K20505N	20505	Missense	distal	4	no	7.267	7.343	EPSD	ICGC;COSMIC	7.092	Up-regulation
AGC_PKG_PRKG1_ST	Q8WZ42	TTN	Q13976	PRKG1	S20559	N20566D	20566	Missense	distal	7	no	9.725	9.682	EPSD	ICGC;COSMIC	7.092	Down-regulation
AGC_PKG_PRKG1_ST	Q8WZ42	TTN	Q13976	PRKG1	S20559	R20556W	20556	Missense	distal	-3	no	9.725	2.053	EPSD	ICGC	7.092	Loss
AGC_PKG_PRKG1_ST	Q8WZ42	TTN	Q13976	PRKG1	S20559	V20552F	20552	Missense	distal	-7	no	9.725	9.942	EPSD	ICGC;COSMIC	7.092	Up-regulation
AGC_PKG_PRKG1_ST	Q8WZ42	TTN	Q13976	PRKG1	S20559	W20562L	20562	Missense	distal	3	no	9.725	9.842	EPSD	ICGC;COSMIC	7.092	Up-regulation
AGC_PKG_PRKG1_ST	Q8WZ42	TTN	Q13976	PRKG1	S20559	R20556L	20556	Missense	distal	-3	no	9.725	2.581	EPSD	ICGC;COSMIC	7.092	Loss
AGC_PKG_PRKG1_ST	Q8WZ42	TTN	Q13976	PRKG1	S20559	N20561S	20561	Missense	proximal	2	no	9.725	9.789	EPSD	ICGC;COSMIC	7.092	Up-regulation
AGC_PKG_PRKG1_ST	Q8WZ42	TTN	Q13976	PRKG1	S20559	S20559F	20559	Missense	central	0	yes	9.725	0.000	EPSD	ICGC;COSMIC	7.092	Loss
AGC_PKG_PRKG1_ST	Q8WZ42	TTN	Q13976	PRKG1	S20759	A20755P	20755	Missense	distal	-4	no	8.049	7.630	EPSD	ICGC;COSMIC	7.092	Down-regulation
AGC_PKG_PRKG1_ST	Q8WZ42	TTN	Q13976	PRKG1	S20759	R20753H	20753	Missense	distal	-6	no	8.049	7.524	EPSD	ICGC;COSMIC	7.092	Down-regulation
AGC_PKG_PRKG1_ST	Q8WZ42	TTN	Q13976	PRKG1	S20759	T20764K	20764	Missense	distal	5	no	8.049	8.058	EPSD	ICGC	7.092	Up-regulation
AGC_PKG_PRKG1_ST	Q8WZ42	TTN	Q13976	PRKG1	S20759	T20762K	20762	Missense	distal	3	no	8.049	8.072	EPSD	ICGC;COSMIC	7.092	Up-regulation
AGC_PKG_PRKG1_ST	Q8WZ42	TTN	Q13976	PRKG1	S20759	R20753C	20753	Missense	distal	-6	no	8.049	7.380	EPSD	ICGC;COSMIC	7.092	Down-regulation
AGC_PKG_PRKG1_ST	Q8WZ42	TTN	Q13976	PRKG1	S20759	T20765A	20765	Missense	distal	6	no	8.049	8.041	EPSD	ICGC;COSMIC	7.092	Down-regulation
AGC_PKG_PRKG1_ST	Q8WZ42	TTN	Q13976	PRKG1	S20761	A20755P	20755	Missense	distal	-6	no	8.369	8.098	EPSD	ICGC;COSMIC	7.092	Down-regulation
AGC_PKG_PRKG1_ST	Q8WZ42	TTN	Q13976	PRKG1	S20761	T20764K	20764	Missense	distal	3	no	8.369	8.393	EPSD	ICGC	7.092	Up-regulation
AGC_PKG_PRKG1_ST	Q8WZ42	TTN	Q13976	PRKG1	S20761	T20762K	20762	Missense	proximal	1	no	8.369	8.466	EPSD	ICGC;COSMIC	7.092	Up-regulation
AGC_PKG_PRKG1_ST	Q8WZ42	TTN	Q13976	PRKG1	S20761	T20765A	20765	Missense	distal	4	no	8.369	8.367	EPSD	ICGC;COSMIC	7.092	Down-regulation
AGC_PKG_PRKG1_ST	Q8WZ42	TTN	Q13976	PRKG1	S20826	K20824T	20824	Missense	proximal	-2	no	7.259	5.144	EPSD	ICGC	7.092	Loss
AGC_PKG_PRKG1_ST	Q8WZ42	TTN	Q13976	PRKG1	S20826	S20821P	20821	Missense	distal	-5	no	7.259	7.373	EPSD	ICGC;COSMIC	7.092	Up-regulation
AGC_PKG_PRKG1_ST	Q8WZ42	TTN	Q13976	PRKG1	S20826	K20832T	20832	Missense	distal	6	no	7.259	7.310	EPSD	ICGC;COSMIC	7.092	Up-regulation
AGC_PKG_PRKG1_ST	Q8WZ42	TTN	Q13976	PRKG1	S20864	Q20857K	20857	Missense	distal	-7	no	7.755	7.966	EPSD	ICGC	7.092	Up-regulation
AGC_PKG_PRKG1_ST	Q8WZ42	TTN	Q13976	PRKG1	S20864	D20871Y	20871	Missense	distal	7	no	7.755	7.774	EPSD	ICGC;COSMIC	7.092	Up-regulation
AGC_PKG_PRKG1_ST	Q8WZ42	TTN	Q13976	PRKG1	S20864	S20864G	20864	Missense	central	0	yes	7.755	0.000	EPSD	ICGC;COSMIC	7.092	Loss
AGC_PKG_PRKG1_ST	Q8WZ42	TTN	Q13976	PRKG1	S20864	S20868P	20868	Missense	distal	4	no	7.755	7.906	EPSD	ICGC;COSMIC	7.092	Up-regulation
AGC_PKG_PRKG1_ST	Q8WZ42	TTN	Q13976	PRKG1	S20864	D20871N	20871	Missense	distal	7	no	7.755	7.798	EPSD	ICGC	7.092	Up-regulation
AGC_PKG_PRKG1_ST	Q8WZ42	TTN	Q13976	PRKG1	S20864	R20858Q	20858	Missense	distal	-6	no	7.755	7.459	EPSD	ICGC;COSMIC	7.092	Down-regulation
AGC_PKG_PRKG1_ST	Q8WZ42	TTN	Q13976	PRKG1	S20864	K20870R	20870	Missense	distal	6	no	7.755	7.694	EPSD	ICGC;COSMIC	7.092	Down-regulation
AGC_PKG_PRKG1_ST	Q8WZ42	TTN	Q13976	PRKG1	T20879	E20877K	20877	Missense	proximal	-2	no	4.566	8.089	EPSD	ICGC;COSMIC	7.092	Gain
AGC_PKG_PRKG1_ST	Q8WZ42	TTN	Q13976	PRKG1	S21045	S21045F	21045	Missense	central	0	yes	9.991	0.000	EPSD	ICGC;COSMIC	7.092	Loss
AGC_PKG_PRKG1_ST	Q8WZ42	TTN	Q13976	PRKG1	S21045	K21042N	21042	Missense	distal	-3	no	9.991	5.445	EPSD	ICGC;COSMIC	7.092	Loss
AGC_PKG_PRKG1_ST	Q8WZ42	TTN	Q13976	PRKG1	S21045	N21048K	21048	Missense	distal	3	no	9.991	9.892	EPSD	ICGC	7.092	Down-regulation
AGC_PKG_PRKG1_ST	Q8WZ42	TTN	Q13976	PRKG1	S21045	S21045Y	21045	Missense	central	0	yes	9.991	0.000	EPSD	ICGC	7.092	Loss
AGC_PKG_PRKG1_ST	Q8WZ42	TTN	Q13976	PRKG1	S21045	V21046E	21046	Missense	proximal	1	no	9.991	10.066	EPSD	ICGC;COSMIC	7.092	Up-regulation
AGC_PKG_PRKG1_ST	Q8WZ42	TTN	Q13976	PRKG1	S21045	D21044N	21044	Missense	proximal	-1	no	9.991	10.069	EPSD	ICGC;COSMIC	7.092	Up-regulation
AGC_PKG_PRKG1_ST	Q8WZ42	TTN	Q13976	PRKG1	S21045	T21052M	21052	Missense	distal	7	no	9.991	9.986	EPSD	ICGC;COSMIC	7.092	Down-regulation
AGC_PKG_PRKG1_ST	Q8WZ42	TTN	Q13976	PRKG1	S21045	D21044Y	21044	Missense	proximal	-1	no	9.991	10.061	EPSD	ICGC;COSMIC	7.092	Up-regulation
AGC_PKG_PRKG1_ST	Q8WZ42	TTN	Q13976	PRKG1	T21061	Q21058R	21058	Missense	distal	-3	no	6.390	10.225	EPSD	ICGC;COSMIC	7.092	Gain
AGC_PKG_PRKG1_ST	Q8WZ42	TTN	Q13976	PRKG1	S21361	S21362P	21362	Missense	proximal	1	no	7.103	6.841	EPSD	ICGC;COSMIC	7.092	Loss
AGC_PKG_PRKG1_ST	Q8WZ42	TTN	Q13976	PRKG1	S21361	S21357L	21357	Missense	distal	-4	no	7.103	6.330	EPSD	ICGC;COSMIC	7.092	Loss
AGC_PKG_PRKG1_ST	Q8WZ42	TTN	Q13976	PRKG1	S21361	T21360K	21360	Missense	proximal	-1	no	7.103	7.147	EPSD	ICGC	7.092	Up-regulation
AGC_PKG_PRKG1_ST	Q8WZ42	TTN	Q13976	PRKG1	S21361	Y21368C	21368	Missense	distal	7	no	7.103	7.113	EPSD	ICGC;COSMIC	7.092	Up-regulation
AGC_PKG_PRKG1_ST	Q8WZ42	TTN	Q13976	PRKG1	S21361	P21359Q	21359	Missense	proximal	-2	no	7.103	7.897	EPSD	ICGC;COSMIC	7.092	Up-regulation
AGC_PKG_PRKG1_ST	Q8WZ42	TTN	Q13976	PRKG1	S21554	T21551K	21551	Missense	distal	-3	no	5.957	8.765	EPSD	ICGC	7.092	Gain
AGC_PKG_PRKG1_ST	Q8WZ42	TTN	Q13976	PRKG1	S21784	N21778K	21778	Missense	distal	-6	no	6.904	7.318	EPSD	ICGC	7.092	Gain
AGC_PKG_PRKG1_ST	Q8WZ42	TTN	Q13976	PRKG1	T21837	E21835G	21835	Missense	proximal	-2	no	5.649	7.161	EPSD	ICGC	7.092	Gain
AGC_PKG_PRKG1_ST	Q8WZ42	TTN	Q13976	PRKG1	S21840	R21834H	21834	Missense	distal	-6	no	10.089	9.564	EPSD	ICGC;COSMIC	7.092	Down-regulation
AGC_PKG_PRKG1_ST	Q8WZ42	TTN	Q13976	PRKG1	S21840	S21842F	21842	Missense	proximal	2	no	10.089	10.012	EPSD	ICGC;COSMIC	7.092	Down-regulation
AGC_PKG_PRKG1_ST	Q8WZ42	TTN	Q13976	PRKG1	S21840	S21842Y	21842	Missense	proximal	2	no	10.089	9.997	EPSD	ICGC	7.092	Down-regulation
AGC_PKG_PRKG1_ST	Q8WZ42	TTN	Q13976	PRKG1	S21840	E21835G	21835	Missense	distal	-5	no	10.089	10.042	EPSD	ICGC	7.092	Down-regulation
AGC_PKG_PRKG1_ST	Q8WZ42	TTN	Q13976	PRKG1	S21840	K21839T	21839	Missense	proximal	-1	no	10.089	10.045	EPSD	ICGC	7.092	Down-regulation
AGC_PKG_PRKG1_ST	Q8WZ42	TTN	Q13976	PRKG1	S21840	R21838Q	21838	Missense	proximal	-2	no	10.089	7.124	EPSD	ICGC;COSMIC	7.092	Down-regulation
AGC_PKG_PRKG1_ST	Q8WZ42	TTN	Q13976	PRKG1	S21840	S21840Y	21840	Missense	central	0	yes	10.089	0.000	EPSD	ICGC;COSMIC	7.092	Loss
AGC_PKG_PRKG1_ST	Q8WZ42	TTN	Q13976	PRKG1	S21840	R21838W	21838	Missense	proximal	-2	no	10.089	4.759	EPSD	ICGC;COSMIC	7.092	Loss
AGC_PKG_PRKG1_ST	Q8WZ42	TTN	Q13976	PRKG1	S21842	S21842F	21842	Missense	central	0	yes	8.314	0.000	EPSD	ICGC;COSMIC	7.092	Loss
AGC_PKG_PRKG1_ST	Q8WZ42	TTN	Q13976	PRKG1	S21842	S21842Y	21842	Missense	central	0	yes	8.314	0.000	EPSD	ICGC	7.092	Loss
AGC_PKG_PRKG1_ST	Q8WZ42	TTN	Q13976	PRKG1	S21842	E21835G	21835	Missense	distal	-7	no	8.314	8.632	EPSD	ICGC	7.092	Up-regulation
AGC_PKG_PRKG1_ST	Q8WZ42	TTN	Q13976	PRKG1	S21842	K21839T	21839	Missense	distal	-3	no	8.314	5.506	EPSD	ICGC	7.092	Loss
AGC_PKG_PRKG1_ST	Q8WZ42	TTN	Q13976	PRKG1	S21842	R21838Q	21838	Missense	distal	-4	no	8.314	7.919	EPSD	ICGC;COSMIC	7.092	Down-regulation
AGC_PKG_PRKG1_ST	Q8WZ42	TTN	Q13976	PRKG1	S21842	S21840Y	21840	Missense	proximal	-2	no	8.314	7.624	EPSD	ICGC;COSMIC	7.092	Down-regulation
AGC_PKG_PRKG1_ST	Q8WZ42	TTN	Q13976	PRKG1	S21842	R21838W	21838	Missense	distal	-4	no	8.314	7.142	EPSD	ICGC;COSMIC	7.092	Down-regulation
AGC_PKG_PRKG1_ST	Q8WZ42	TTN	Q13976	PRKG1	S21935	I21928N	21928	Missense	distal	-7	no	11.333	12.103	EPSD	ICGC;COSMIC	7.092	Up-regulation
AGC_PKG_PRKG1_ST	Q8WZ42	TTN	Q13976	PRKG1	S21935	G21934S	21934	Missense	proximal	-1	no	11.333	11.396	EPSD	ICGC;COSMIC	7.092	Up-regulation
AGC_PKG_PRKG1_ST	Q8WZ42	TTN	Q13976	PRKG1	S21935	T21942P	21942	Missense	distal	7	no	11.333	11.242	EPSD	ICGC;COSMIC	7.092	Down-regulation
AGC_PKG_PRKG1_ST	Q8WZ42	TTN	Q13976	PRKG1	S22060	L22065S	22065	Missense	distal	5	no	7.662	7.778	EPSD	ICGC;COSMIC	7.092	Up-regulation
AGC_PKG_PRKG1_ST	Q8WZ42	TTN	Q13976	PRKG1	S22060	A22067T	22067	Missense	distal	7	no	7.662	7.672	EPSD	ICGC	7.092	Up-regulation
AGC_PKG_PRKG1_ST	Q8WZ42	TTN	Q13976	PRKG1	T22152	L22154S	22154	Missense	proximal	2	no	7.016	7.159	EPSD	ICGC;COSMIC	7.092	Gain
AGC_PKG_PRKG1_ST	Q8WZ42	TTN	Q13976	PRKG1	S22272	M22278I	22278	Missense	distal	6	no	6.981	7.260	EPSD	ICGC	7.092	Gain
AGC_PKG_PRKG1_ST	Q8WZ42	TTN	Q13976	PRKG1	S22275	P22274T	22274	Missense	proximal	-1	no	8.026	8.128	EPSD	ICGC;COSMIC	7.092	Up-regulation
AGC_PKG_PRKG1_ST	Q8WZ42	TTN	Q13976	PRKG1	S22275	L22281P	22281	Missense	distal	6	no	8.026	7.898	EPSD	ICGC;COSMIC	7.092	Down-regulation
AGC_PKG_PRKG1_ST	Q8WZ42	TTN	Q13976	PRKG1	S22275	M22278I	22278	Missense	distal	3	no	8.026	8.310	EPSD	ICGC	7.092	Up-regulation
AGC_PKG_PRKG1_ST	Q8WZ42	TTN	Q13976	PRKG1	S22456	A22463V	22463	Missense	distal	7	no	14.351	14.280	EPSD	ICGC	7.092	Down-regulation
AGC_PKG_PRKG1_ST	Q8WZ42	TTN	Q13976	PRKG1	S22456	T22460N	22460	Missense	distal	4	no	14.351	14.409	EPSD	ICGC	7.092	Up-regulation
AGC_PKG_PRKG1_ST	Q8WZ42	TTN	Q13976	PRKG1	S22456	A22458D	22458	Missense	proximal	2	no	14.351	14.289	EPSD	ICGC	7.092	Down-regulation
AGC_PKG_PRKG1_ST	Q8WZ42	TTN	Q13976	PRKG1	S22456	G22457D	22457	Missense	proximal	1	no	14.351	14.206	EPSD	ICGC;COSMIC	7.092	Down-regulation
AGC_PKG_PRKG1_ST	Q8WZ42	TTN	Q13976	PRKG1	S22456	S22451L	22451	Missense	distal	-5	no	14.351	14.587	EPSD	ICGC;COSMIC	7.092	Up-regulation
AGC_PKG_PRKG1_ST	Q8WZ42	TTN	Q13976	PRKG1	S22456	D22455N	22455	Missense	proximal	-1	no	14.351	14.428	EPSD	ICGC;COSMIC	7.092	Up-regulation
AGC_PKG_PRKG1_ST	Q8WZ42	TTN	Q13976	PRKG1	S22456	R22454M	22454	Missense	proximal	-2	no	14.351	11.088	EPSD	ICGC;COSMIC	7.092	Down-regulation
AGC_PKG_PRKG1_ST	Q8WZ42	TTN	Q13976	PRKG1	S22853	G22846A	22846	Missense	distal	-7	no	9.328	9.686	EPSD	ICGC;COSMIC	7.092	Up-regulation
AGC_PKG_PRKG1_ST	Q8WZ42	TTN	Q13976	PRKG1	S22853	S22853R	22853	Missense	central	0	yes	9.328	0.000	EPSD	ICGC;COSMIC	7.092	Loss
AGC_PKG_PRKG1_ST	Q8WZ42	TTN	Q13976	PRKG1	S22926	R22922T	22922	Missense	distal	-4	no	8.516	7.928	EPSD	ICGC;COSMIC	7.092	Down-regulation
AGC_PKG_PRKG1_ST	Q8WZ42	TTN	Q13976	PRKG1	S22926	R22922I	22922	Missense	distal	-4	no	8.516	7.207	EPSD	ICGC;COSMIC	7.092	Down-regulation
AGC_PKG_PRKG1_ST	Q8WZ42	TTN	Q13976	PRKG1	S22926	K22923N	22923	Missense	distal	-3	no	8.516	3.969	EPSD	ICGC	7.092	Loss
AGC_PKG_PRKG1_ST	Q8WZ42	TTN	Q13976	PRKG1	S22926	T22930P	22930	Missense	distal	4	no	8.516	8.644	EPSD	ICGC;COSMIC	7.092	Up-regulation
AGC_PKG_PRKG1_ST	Q8WZ42	TTN	Q13976	PRKG1	S22926	C22932Y	22932	Missense	distal	6	no	8.516	8.531	EPSD	ICGC;COSMIC	7.092	Up-regulation
AGC_PKG_PRKG1_ST	Q8WZ42	TTN	Q13976	PRKG1	S23063	D23070Y	23070	Missense	distal	7	no	8.370	8.388	EPSD	ICGC;COSMIC	7.092	Up-regulation
AGC_PKG_PRKG1_ST	Q8WZ42	TTN	Q13976	PRKG1	S23063	R23060T	23060	Missense	distal	-3	no	8.370	3.204	EPSD	ICGC;COSMIC	7.092	Loss
AGC_PKG_PRKG1_ST	Q8WZ42	TTN	Q13976	PRKG1	S23063	S23057N	23057	Missense	distal	-6	no	8.370	8.089	EPSD	ICGC;COSMIC	7.092	Down-regulation
AGC_PKG_PRKG1_ST	Q8WZ42	TTN	Q13976	PRKG1	S23063	S23057G	23057	Missense	distal	-6	no	8.370	8.152	EPSD	ICGC;COSMIC	7.092	Down-regulation
AGC_PKG_PRKG1_ST	Q8WZ42	TTN	Q13976	PRKG1	S23063	K23069N	23069	Missense	distal	6	no	8.370	8.524	EPSD	ICGC;COSMIC	7.092	Up-regulation
AGC_PKG_PRKG1_ST	Q8WZ42	TTN	Q13976	PRKG1	S23063	A23068T	23068	Missense	distal	5	no	8.370	8.380	EPSD	ICGC;COSMIC	7.092	Up-regulation
AGC_PKG_PRKG1_ST	Q8WZ42	TTN	Q13976	PRKG1	T23210	E23206D	23206	Missense	distal	-4	no	8.444	8.299	EPSD	ICGC;COSMIC	7.092	Down-regulation
AGC_PKG_PRKG1_ST	Q8WZ42	TTN	Q13976	PRKG1	T23210	R23208W	23208	Missense	proximal	-2	no	8.444	3.114	EPSD	ICGC;COSMIC	7.092	Loss
AGC_PKG_PRKG1_ST	Q8WZ42	TTN	Q13976	PRKG1	T23210	I23217N	23217	Missense	distal	7	no	8.444	8.532	EPSD	ICGC;COSMIC	7.092	Up-regulation
AGC_PKG_PRKG1_ST	Q8WZ42	TTN	Q13976	PRKG1	T23210	R23208Q	23208	Missense	proximal	-2	no	8.444	5.480	EPSD	ICGC;COSMIC	7.092	Loss
AGC_PKG_PRKG1_ST	Q8WZ42	TTN	Q13976	PRKG1	T23226	C23230F	23230	Missense	distal	4	no	7.298	7.303	EPSD	ICGC;COSMIC	7.092	Up-regulation
AGC_PKG_PRKG1_ST	Q8WZ42	TTN	Q13976	PRKG1	T23226	A23220T	23220	Missense	distal	-6	no	7.298	7.259	EPSD	ICGC	7.092	Down-regulation
AGC_PKG_PRKG1_ST	Q8WZ42	TTN	Q13976	PRKG1	T23226	K23228N	23228	Missense	proximal	2	no	7.298	7.262	EPSD	ICGC	7.092	Down-regulation
AGC_PKG_PRKG1_ST	Q8WZ42	TTN	Q13976	PRKG1	S23251	G23249R	23249	Missense	proximal	-2	no	5.848	9.335	EPSD	ICGC;COSMIC	7.092	Gain
AGC_PKG_PRKG1_ST	Q8WZ42	TTN	Q13976	PRKG1	T23252	G23249R	23249	Missense	distal	-3	no	4.115	8.705	EPSD	ICGC;COSMIC	7.092	Gain
AGC_PKG_PRKG1_ST	Q8WZ42	TTN	Q13976	PRKG1	S23311	E23308K	23308	Missense	distal	-3	no	5.858	10.441	EPSD	ICGC;COSMIC	7.092	Gain
AGC_PKG_PRKG1_ST	Q8WZ42	TTN	Q13976	PRKG1	S23354	I23347S	23347	Missense	distal	-7	no	5.912	7.291	EPSD	ICGC	7.092	Gain
AGC_PKG_PRKG1_ST	Q8WZ42	TTN	Q13976	PRKG1	S23381	A23374E	23374	Missense	distal	-7	no	7.465	6.788	EPSD	ICGC	7.092	Loss
AGC_PKG_PRKG1_ST	Q8WZ42	TTN	Q13976	PRKG1	S23381	S23381Y	23381	Missense	central	0	yes	7.465	0.000	EPSD	ICGC;COSMIC	7.092	Loss
AGC_PKG_PRKG1_ST	Q8WZ42	TTN	Q13976	PRKG1	S23381	L23384I	23384	Missense	distal	3	no	7.465	7.416	EPSD	ICGC;COSMIC	7.092	Down-regulation
AGC_PKG_PRKG1_ST	Q8WZ42	TTN	Q13976	PRKG1	S23471	P23467S	23467	Missense	distal	-4	no	7.287	7.710	EPSD	ICGC;COSMIC	7.092	Up-regulation
AGC_PKG_PRKG1_ST	Q8WZ42	TTN	Q13976	PRKG1	S23471	P23468T	23468	Missense	distal	-3	no	7.287	7.023	EPSD	ICGC	7.092	Loss
AGC_PKG_PRKG1_ST	Q8WZ42	TTN	Q13976	PRKG1	S23471	P23474S	23474	Missense	distal	3	no	7.287	7.037	EPSD	ICGC;COSMIC	7.092	Loss
AGC_PKG_PRKG1_ST	Q8WZ42	TTN	Q13976	PRKG1	S23471	R23469Q	23469	Missense	proximal	-2	no	7.287	4.322	EPSD	ICGC;COSMIC	7.092	Loss
AGC_PKG_PRKG1_ST	Q8WZ42	TTN	Q13976	PRKG1	S23553	E23551K	23551	Missense	proximal	-2	no	5.927	9.449	EPSD	ICGC;COSMIC	7.092	Gain
AGC_PKG_PRKG1_ST	Q8WZ42	TTN	Q13976	PRKG1	T23555	E23551K	23551	Missense	distal	-4	no	8.643	9.304	EPSD	ICGC;COSMIC	7.092	Up-regulation
AGC_PKG_PRKG1_ST	Q8WZ42	TTN	Q13976	PRKG1	T23555	L23561I	23561	Missense	distal	6	no	8.643	8.611	EPSD	ICGC	7.092	Down-regulation
AGC_PKG_PRKG1_ST	Q8WZ42	TTN	Q13976	PRKG1	T23555	G23550V	23550	Missense	distal	-5	no	8.643	8.680	EPSD	ICGC;COSMIC;CCLE	7.092	Up-regulation
AGC_PKG_PRKG1_ST	Q8WZ42	TTN	Q13976	PRKG1	T23555	G23550E	23550	Missense	distal	-5	no	8.643	8.690	EPSD	ICGC	7.092	Up-regulation
AGC_PKG_PRKG1_ST	Q8WZ42	TTN	Q13976	PRKG1	T23898	R23896H	23896	Missense	proximal	-2	no	8.004	3.746	EPSD	ICGC;COSMIC	7.092	Loss
AGC_PKG_PRKG1_ST	Q8WZ42	TTN	Q13976	PRKG1	T23898	E23900D	23900	Missense	proximal	2	no	8.004	7.995	EPSD	ICGC	7.092	Down-regulation
AGC_PKG_PRKG1_ST	Q8WZ42	TTN	Q13976	PRKG1	T23898	P23892T	23892	Missense	distal	-6	no	8.004	8.236	EPSD	ICGC;COSMIC	7.092	Up-regulation
AGC_PKG_PRKG1_ST	Q8WZ42	TTN	Q13976	PRKG1	T23898	I23893M	23893	Missense	distal	-5	no	8.004	7.798	EPSD	ICGC;COSMIC	7.092	Down-regulation
AGC_PKG_PRKG1_ST	Q8WZ42	TTN	Q13976	PRKG1	T23898	R23896C	23896	Missense	proximal	-2	no	8.004	3.275	EPSD	ICGC;COSMIC	7.092	Loss
AGC_PKG_PRKG1_ST	Q8WZ42	TTN	Q13976	PRKG1	T23898	P23897L	23897	Missense	proximal	-1	no	8.004	7.906	EPSD	ICGC;COSMIC	7.092	Down-regulation
AGC_PKG_PRKG1_ST	Q8WZ42	TTN	Q13976	PRKG1	T23898	V23901G	23901	Missense	distal	3	no	8.004	7.939	EPSD	ICGC;COSMIC	7.092	Down-regulation
AGC_PKG_PRKG1_ST	Q8WZ42	TTN	Q13976	PRKG1	T23939	Y23933H	23933	Missense	distal	-6	no	7.554	7.690	EPSD	ICGC;COSMIC	7.092	Up-regulation
AGC_PKG_PRKG1_ST	Q8WZ42	TTN	Q13976	PRKG1	T23939	R23932Q	23932	Missense	distal	-7	no	7.554	6.878	EPSD	ICGC;COSMIC	7.092	Loss
AGC_PKG_PRKG1_ST	Q8WZ42	TTN	Q13976	PRKG1	T23939	L23942S	23942	Missense	distal	3	no	7.554	7.186	EPSD	ICGC;COSMIC	7.092	Down-regulation
AGC_PKG_PRKG1_ST	Q8WZ42	TTN	Q13976	PRKG1	T23939	E23943Q	23943	Missense	distal	4	no	7.554	7.458	EPSD	ICGC;COSMIC	7.092	Down-regulation
AGC_PKG_PRKG1_ST	Q8WZ42	TTN	Q13976	PRKG1	T23939	G23936R	23936	Missense	distal	-3	no	7.554	12.145	EPSD	ICGC	7.092	Up-regulation
AGC_PKG_PRKG1_ST	Q8WZ42	TTN	Q13976	PRKG1	T23939	D23934Y	23934	Missense	distal	-5	no	7.554	7.494	EPSD	ICGC;COSMIC	7.092	Down-regulation
AGC_PKG_PRKG1_ST	Q8WZ42	TTN	Q13976	PRKG1	T23939	E23943K	23943	Missense	distal	4	no	7.554	7.439	EPSD	ICGC;COSMIC	7.092	Down-regulation
AGC_PKG_PRKG1_ST	Q8WZ42	TTN	Q13976	PRKG1	T23939	G23936E	23936	Missense	distal	-3	no	7.554	5.204	EPSD	ICGC;COSMIC	7.092	Loss
AGC_PKG_PRKG1_ST	Q8WZ42	TTN	Q13976	PRKG1	S24006	R24000S	24000	Missense	distal	-6	no	9.473	9.176	EPSD	ICGC	7.092	Down-regulation
AGC_PKG_PRKG1_ST	Q8WZ42	TTN	Q13976	PRKG1	S24006	N24013S	24013	Missense	distal	7	no	9.473	9.532	EPSD	ICGC;COSMIC	7.092	Up-regulation
AGC_PKG_PRKG1_ST	Q8WZ42	TTN	Q13976	PRKG1	S24006	R24000C	24000	Missense	distal	-6	no	9.473	8.805	EPSD	ICGC	7.092	Down-regulation
AGC_PKG_PRKG1_ST	Q8WZ42	TTN	Q13976	PRKG1	S24112	A24108V	24108	Missense	distal	-4	no	10.058	9.532	EPSD	ICGC;COSMIC	7.092	Down-regulation
AGC_PKG_PRKG1_ST	Q8WZ42	TTN	Q13976	PRKG1	S24112	N24119S	24119	Missense	distal	7	no	10.058	10.118	EPSD	ICGC;COSMIC	7.092	Up-regulation
AGC_PKG_PRKG1_ST	Q8WZ42	TTN	Q13976	PRKG1	S24112	Q24114K	24114	Missense	proximal	2	no	10.058	10.050	EPSD	ICGC	7.092	Down-regulation
AGC_PKG_PRKG1_ST	Q8WZ42	TTN	Q13976	PRKG1	S24112	S24112F	24112	Missense	central	0	yes	10.058	0.000	EPSD	ICGC	7.092	Loss
AGC_PKG_PRKG1_ST	Q8WZ42	TTN	Q13976	PRKG1	S24112	E24106K	24106	Missense	distal	-6	no	10.058	10.539	EPSD	ICGC;COSMIC	7.092	Up-regulation
AGC_PKG_PRKG1_ST	Q8WZ42	TTN	Q13976	PRKG1	S24112	A24115V	24115	Missense	distal	3	no	10.058	10.260	EPSD	ICGC	7.092	Up-regulation
AGC_PKG_PRKG1_ST	Q8WZ42	TTN	Q13976	PRKG1	S24112	S24112Y	24112	Missense	central	0	yes	10.058	0.000	EPSD	ICGC;COSMIC	7.092	Loss
AGC_PKG_PRKG1_ST	Q8WZ42	TTN	Q13976	PRKG1	S24112	R24109Q	24109	Missense	distal	-3	no	10.058	6.224	EPSD	ICGC;COSMIC	7.092	Loss
AGC_PKG_PRKG1_ST	Q8WZ42	TTN	Q13976	PRKG1	S24167	Q24169K	24169	Missense	proximal	2	no	7.230	7.222	EPSD	ICGC	7.092	Down-regulation
AGC_PKG_PRKG1_ST	Q8WZ42	TTN	Q13976	PRKG1	S24241	T24239A	24239	Missense	proximal	-2	no	8.524	8.660	EPSD	ICGC;COSMIC	7.092	Up-regulation
AGC_PKG_PRKG1_ST	Q8WZ42	TTN	Q13976	PRKG1	S24241	G24236A	24236	Missense	distal	-5	no	8.524	8.436	EPSD	ICGC;COSMIC	7.092	Down-regulation
AGC_PKG_PRKG1_ST	Q8WZ42	TTN	Q13976	PRKG1	S24241	E24243K	24243	Missense	proximal	2	no	8.524	8.575	EPSD	ICGC;COSMIC	7.092	Up-regulation
AGC_PKG_PRKG1_ST	Q8WZ42	TTN	Q13976	PRKG1	S24241	L24247I	24247	Missense	distal	6	no	8.524	8.492	EPSD	ICGC;COSMIC	7.092	Down-regulation
AGC_PKG_PRKG1_ST	Q8WZ42	TTN	Q13976	PRKG1	S24393	E24390K	24390	Missense	distal	-3	no	5.084	9.667	EPSD	ICGC;COSMIC	7.092	Gain
AGC_PKG_PRKG1_ST	Q8WZ42	TTN	Q13976	PRKG1	S24635	A24631T	24631	Missense	distal	-4	no	8.010	7.896	EPSD	ICGC	7.092	Down-regulation
AGC_PKG_PRKG1_ST	Q8WZ42	TTN	Q13976	PRKG1	S24635	S24628F	24628	Missense	distal	-7	no	8.010	7.365	EPSD	ICGC;COSMIC	7.092	Down-regulation
AGC_PKG_PRKG1_ST	Q8WZ42	TTN	Q13976	PRKG1	S24635	K24641T	24641	Missense	distal	6	no	8.010	8.061	EPSD	ICGC;COSMIC	7.092	Up-regulation
AGC_PKG_PRKG1_ST	Q8WZ42	TTN	Q13976	PRKG1	S24664	E24661K	24661	Missense	distal	-3	no	4.788	9.371	EPSD	ICGC;COSMIC;CCLE	7.092	Gain
AGC_PKG_PRKG1_ST	Q8WZ42	TTN	Q13976	PRKG1	T24688	E24684Q	24684	Missense	distal	-4	no	9.393	9.962	EPSD	ICGC;COSMIC	7.092	Up-regulation
AGC_PKG_PRKG1_ST	Q8WZ42	TTN	Q13976	PRKG1	T24688	R24690Q	24690	Missense	proximal	2	no	9.393	9.386	EPSD	ICGC;COSMIC;CCLE	7.092	Down-regulation
AGC_PKG_PRKG1_ST	Q8WZ42	TTN	Q13976	PRKG1	T24688	R24686Q	24686	Missense	proximal	-2	no	9.393	6.428	EPSD	ICGC;COSMIC	7.092	Loss
AGC_PKG_PRKG1_ST	Q8WZ42	TTN	Q13976	PRKG1	T24688	E24687K	24687	Missense	proximal	-1	no	9.393	9.554	EPSD	ICGC;COSMIC	7.092	Up-regulation
AGC_PKG_PRKG1_ST	Q8WZ42	TTN	Q13976	PRKG1	S24689	E24684Q	24684	Missense	distal	-5	no	7.156	7.003	EPSD	ICGC;COSMIC	7.092	Loss
AGC_PKG_PRKG1_ST	Q8WZ42	TTN	Q13976	PRKG1	S24689	R24690Q	24690	Missense	proximal	1	no	7.156	6.992	EPSD	ICGC;COSMIC;CCLE	7.092	Loss
AGC_PKG_PRKG1_ST	Q8WZ42	TTN	Q13976	PRKG1	S24689	R24686Q	24686	Missense	distal	-3	no	7.156	3.322	EPSD	ICGC;COSMIC	7.092	Loss
AGC_PKG_PRKG1_ST	Q8WZ42	TTN	Q13976	PRKG1	S24689	E24687K	24687	Missense	proximal	-2	no	7.156	10.679	EPSD	ICGC;COSMIC	7.092	Up-regulation
AGC_PKG_PRKG1_ST	Q8WZ42	TTN	Q13976	PRKG1	S24689	T24688S	24688	Missense	proximal	-1	no	7.156	7.158	EPSD	ICGC;COSMIC	7.092	Up-regulation
AGC_PKG_PRKG1_ST	Q8WZ42	TTN	Q13976	PRKG1	S24761	K24759R	24759	Missense	proximal	-2	no	7.855	9.332	EPSD	ICGC;COSMIC	7.092	Up-regulation
AGC_PKG_PRKG1_ST	Q8WZ42	TTN	Q13976	PRKG1	S24761	V24764I	24764	Missense	distal	3	no	7.855	7.949	EPSD	ICGC;COSMIC	7.092	Up-regulation
AGC_PKG_PRKG1_ST	Q8WZ42	TTN	Q13976	PRKG1	S24761	T24755A	24755	Missense	distal	-6	no	7.855	7.895	EPSD	ICGC;COSMIC	7.092	Up-regulation
AGC_PKG_PRKG1_ST	Q8WZ42	TTN	Q13976	PRKG1	S24761	A24758V	24758	Missense	distal	-3	no	7.855	6.753	EPSD	ICGC;COSMIC	7.092	Loss
AGC_PKG_PRKG1_ST	Q8WZ42	TTN	Q13976	PRKG1	S24761	R24768S	24768	Missense	distal	7	no	7.855	7.817	EPSD	ICGC;COSMIC	7.092	Down-regulation
AGC_PKG_PRKG1_ST	Q8WZ42	TTN	Q13976	PRKG1	S24761	T24755K	24755	Missense	distal	-6	no	7.855	8.071	EPSD	ICGC	7.092	Up-regulation
AGC_PKG_PRKG1_ST	Q8WZ42	TTN	Q13976	PRKG1	S24761	D24760E	24760	Missense	proximal	-1	no	7.855	7.898	EPSD	ICGC	7.092	Up-regulation
AGC_PKG_PRKG1_ST	Q8WZ42	TTN	Q13976	PRKG1	S24761	A24758T	24758	Missense	distal	-3	no	7.855	7.268	EPSD	ICGC;COSMIC	7.092	Down-regulation
AGC_PKG_PRKG1_ST	Q8WZ42	TTN	Q13976	PRKG1	S24761	S24761C	24761	Missense	central	0	yes	7.855	0.000	EPSD	ICGC;COSMIC	7.092	Loss
AGC_PKG_PRKG1_ST	Q8WZ42	TTN	Q13976	PRKG1	S24761	M24762I	24762	Missense	proximal	1	no	7.855	7.497	EPSD	ICGC;COSMIC	7.092	Down-regulation
AGC_PKG_PRKG1_ST	Q8WZ42	TTN	Q13976	PRKG1	S24761	R24768C	24768	Missense	distal	7	no	7.855	7.743	EPSD	ICGC;COSMIC	7.092	Down-regulation
AGC_PKG_PRKG1_ST	Q8WZ42	TTN	Q13976	PRKG1	S24761	S24761Y	24761	Missense	central	0	yes	7.855	0.000	EPSD	ICGC;COSMIC	7.092	Loss
AGC_PKG_PRKG1_ST	Q8WZ42	TTN	Q13976	PRKG1	S24788	I24781T	24781	Missense	distal	-7	no	7.034	8.199	EPSD	ICGC;COSMIC	7.092	Gain
AGC_PKG_PRKG1_ST	Q8WZ42	TTN	Q13976	PRKG1	S24788	D24786E	24786	Missense	proximal	-2	no	7.034	7.937	EPSD	ICGC;COSMIC	7.092	Gain
AGC_PKG_PRKG1_ST	Q8WZ42	TTN	Q13976	PRKG1	S24788	I24781N	24781	Missense	distal	-7	no	7.034	7.804	EPSD	ICGC;COSMIC	7.092	Gain
AGC_PKG_PRKG1_ST	Q8WZ42	TTN	Q13976	PRKG1	S24788	D24786G	24786	Missense	proximal	-2	no	7.034	9.449	EPSD	ICGC;COSMIC	7.092	Gain
AGC_PKG_PRKG1_ST	Q8WZ42	TTN	Q13976	PRKG1	T24801	R24804H	24804	Missense	distal	3	no	11.912	12.068	EPSD	ICGC;COSMIC	7.092	Up-regulation
AGC_PKG_PRKG1_ST	Q8WZ42	TTN	Q13976	PRKG1	T24801	T24801A	24801	Missense	central	0	yes	11.912	0.000	EPSD	ICGC;COSMIC	7.092	Loss
AGC_PKG_PRKG1_ST	Q8WZ42	TTN	Q13976	PRKG1	T24801	L24805I	24805	Missense	distal	4	no	11.912	11.883	EPSD	ICGC;COSMIC	7.092	Down-regulation
AGC_PKG_PRKG1_ST	Q8WZ42	TTN	Q13976	PRKG1	T24801	R24798H	24798	Missense	distal	-3	no	11.912	5.845	EPSD	ICGC;COSMIC;CCLE	7.092	Loss
AGC_PKG_PRKG1_ST	Q8WZ42	TTN	Q13976	PRKG1	T24801	R24798C	24798	Missense	distal	-3	no	11.912	4.890	EPSD	ICGC;COSMIC;CCLE	7.092	Loss
AGC_PKG_PRKG1_ST	Q8WZ42	TTN	Q13976	PRKG1	T24801	T24808I	24808	Missense	distal	7	no	11.912	11.777	EPSD	ICGC;COSMIC	7.092	Down-regulation
AGC_PKG_PRKG1_ST	Q8WZ42	TTN	Q13976	PRKG1	S25030	S25027R	25027	Missense	distal	-3	no	4.363	9.851	EPSD	ICGC	7.092	Gain
AGC_PKG_PRKG1_ST	Q8WZ42	TTN	Q13976	PRKG1	S25097	V25092L	25092	Missense	distal	-5	no	7.575	7.688	EPSD	ICGC;COSMIC	7.092	Up-regulation
AGC_PKG_PRKG1_ST	Q8WZ42	TTN	Q13976	PRKG1	S25097	V25092E	25092	Missense	distal	-5	no	7.575	7.585	EPSD	ICGC;COSMIC	7.092	Up-regulation
AGC_PKG_PRKG1_ST	Q8WZ42	TTN	Q13976	PRKG1	S25097	K25102E	25102	Missense	distal	5	no	7.575	7.512	EPSD	ICGC;COSMIC	7.092	Down-regulation
AGC_PKG_PRKG1_ST	Q8WZ42	TTN	Q13976	PRKG1	S25097	N25091I	25091	Missense	distal	-6	no	7.575	7.220	EPSD	ICGC	7.092	Down-regulation
AGC_PKG_PRKG1_ST	Q8WZ42	TTN	Q13976	PRKG1	S25097	T25099A	25099	Missense	proximal	2	no	7.575	7.582	EPSD	ICGC;COSMIC	7.092	Up-regulation
AGC_PKG_PRKG1_ST	Q8WZ42	TTN	Q13976	PRKG1	T25374	I25368V	25368	Missense	distal	-6	no	8.716	8.971	EPSD	ICGC;COSMIC	7.092	Up-regulation
AGC_PKG_PRKG1_ST	Q8WZ42	TTN	Q13976	PRKG1	T25437	P25435R	25435	Missense	proximal	-2	no	4.335	8.094	EPSD	ICGC;COSMIC	7.092	Gain
AGC_PKG_PRKG1_ST	Q8WZ42	TTN	Q13976	PRKG1	S25718	T25716K	25716	Missense	proximal	-2	no	6.079	8.194	EPSD	ICGC;COSMIC	7.092	Gain
AGC_PKG_PRKG1_ST	Q8WZ42	TTN	Q13976	PRKG1	S25898	E25895K	25895	Missense	distal	-3	no	4.101	8.684	EPSD	ICGC;COSMIC	7.092	Gain
AGC_PKG_PRKG1_ST	Q8WZ42	TTN	Q13976	PRKG1	S26248	G26250D	26250	Missense	proximal	2	no	7.560	7.544	EPSD	ICGC;COSMIC	7.092	Down-regulation
AGC_PKG_PRKG1_ST	Q8WZ42	TTN	Q13976	PRKG1	S26266	C26272Y	26272	Missense	distal	6	no	7.090	7.105	EPSD	ICGC;COSMIC	7.092	Gain
AGC_PKG_PRKG1_ST	Q8WZ42	TTN	Q13976	PRKG1	S26266	C26272F	26272	Missense	distal	6	no	7.090	7.103	EPSD	ICGC;COSMIC	7.092	Gain
AGC_PKG_PRKG1_ST	Q8WZ42	TTN	Q13976	PRKG1	S26266	E26267K	26267	Missense	proximal	1	no	7.090	7.396	EPSD	ICGC;COSMIC	7.092	Gain
AGC_PKG_PRKG1_ST	Q8WZ42	TTN	Q13976	PRKG1	S26270	E26267K	26267	Missense	distal	-3	no	6.117	10.700	EPSD	ICGC;COSMIC	7.092	Gain
AGC_PKG_PRKG1_ST	Q8WZ42	TTN	Q13976	PRKG1	S26465	H26462R	26462	Missense	distal	-3	no	1.388	7.456	EPSD	ICGC	7.092	Gain
AGC_PKG_PRKG1_ST	Q8WZ42	TTN	Q13976	PRKG1	S26472	L26478P	26478	Missense	distal	6	no	9.482	9.354	EPSD	ICGC	7.092	Down-regulation
AGC_PKG_PRKG1_ST	Q8WZ42	TTN	Q13976	PRKG1	S26472	R26470K	26470	Missense	proximal	-2	no	9.482	8.005	EPSD	ICGC	7.092	Down-regulation
AGC_PKG_PRKG1_ST	Q8WZ42	TTN	Q13976	PRKG1	S26472	R26477H	26477	Missense	distal	5	no	9.482	9.433	EPSD	ICGC;COSMIC	7.092	Down-regulation
AGC_PKG_PRKG1_ST	Q8WZ42	TTN	Q13976	PRKG1	S26472	S26465P	26465	Missense	distal	-7	no	9.482	8.715	EPSD	ICGC	7.092	Down-regulation
AGC_PKG_PRKG1_ST	Q8WZ42	TTN	Q13976	PRKG1	S26472	V26468I	26468	Missense	distal	-4	no	9.482	9.173	EPSD	ICGC	7.092	Down-regulation
AGC_PKG_PRKG1_ST	Q8WZ42	TTN	Q13976	PRKG1	T26480	L26478P	26478	Missense	proximal	-2	no	6.869	8.404	EPSD	ICGC	7.092	Gain
AGC_PKG_PRKG1_ST	Q8WZ42	TTN	Q13976	PRKG1	S26556	E26554K	26554	Missense	proximal	-2	no	4.524	8.047	EPSD	ICGC;COSMIC	7.092	Gain
AGC_PKG_PRKG1_ST	Q8WZ42	TTN	Q13976	PRKG1	S26557	E26554K	26554	Missense	distal	-3	no	5.189	9.772	EPSD	ICGC;COSMIC	7.092	Gain
AGC_PKG_PRKG1_ST	Q8WZ42	TTN	Q13976	PRKG1	S26576	D26579N	26579	Missense	distal	3	no	8.943	8.855	EPSD	ICGC;COSMIC	7.092	Down-regulation
AGC_PKG_PRKG1_ST	Q8WZ42	TTN	Q13976	PRKG1	S26576	G26577S	26577	Missense	proximal	1	no	8.943	9.133	EPSD	ICGC;COSMIC	7.092	Up-regulation
AGC_PKG_PRKG1_ST	Q8WZ42	TTN	Q13976	PRKG1	S26576	M26583L	26583	Missense	distal	7	no	8.943	8.793	EPSD	ICGC;COSMIC	7.092	Down-regulation
AGC_PKG_PRKG1_ST	Q8WZ42	TTN	Q13976	PRKG1	S26576	A26569V	26569	Missense	distal	-7	no	8.943	8.241	EPSD	ICGC	7.092	Down-regulation
AGC_PKG_PRKG1_ST	Q8WZ42	TTN	Q13976	PRKG1	S26576	M26573I	26573	Missense	distal	-3	no	8.943	5.740	EPSD	ICGC	7.092	Loss
AGC_PKG_PRKG1_ST	Q8WZ42	TTN	Q13976	PRKG1	T26784	D26778H	26778	Missense	distal	-6	no	10.269	10.533	EPSD	ICGC;COSMIC	7.092	Up-regulation
AGC_PKG_PRKG1_ST	Q8WZ42	TTN	Q13976	PRKG1	T26784	Q26786K	26786	Missense	proximal	2	no	10.269	10.260	EPSD	ICGC	7.092	Down-regulation
AGC_PKG_PRKG1_ST	Q8WZ42	TTN	Q13976	PRKG1	T26784	G26785V	26785	Missense	proximal	1	no	10.269	10.123	EPSD	ICGC	7.092	Down-regulation
AGC_PKG_PRKG1_ST	Q8WZ42	TTN	Q13976	PRKG1	T26784	R26782L	26782	Missense	proximal	-2	no	10.269	4.975	EPSD	ICGC;COSMIC	7.092	Loss
AGC_PKG_PRKG1_ST	Q8WZ42	TTN	Q13976	PRKG1	T26784	R26782Q	26782	Missense	proximal	-2	no	10.269	7.304	EPSD	ICGC	7.092	Down-regulation
AGC_PKG_PRKG1_ST	Q8WZ42	TTN	Q13976	PRKG1	S26799	R26798Q	26798	Missense	proximal	-1	no	7.502	7.437	EPSD	ICGC;COSMIC	7.092	Down-regulation
AGC_PKG_PRKG1_ST	Q8WZ42	TTN	Q13976	PRKG1	S26799	A26801V	26801	Missense	proximal	2	no	7.502	7.418	EPSD	ICGC;COSMIC	7.092	Down-regulation
AGC_PKG_PRKG1_ST	Q8WZ42	TTN	Q13976	PRKG1	S26799	V26802I	26802	Missense	distal	3	no	7.502	7.596	EPSD	ICGC;COSMIC	7.092	Up-regulation
AGC_PKG_PRKG1_ST	Q8WZ42	TTN	Q13976	PRKG1	S26799	R26798W	26798	Missense	proximal	-1	no	7.502	7.245	EPSD	ICGC;COSMIC	7.092	Down-regulation
AGC_PKG_PRKG1_ST	Q8WZ42	TTN	Q13976	PRKG1	S26799	R26798L	26798	Missense	proximal	-1	no	7.502	7.200	EPSD	ICGC;COSMIC	7.092	Down-regulation
AGC_PKG_PRKG1_ST	Q8WZ42	TTN	Q13976	PRKG1	S26971	K26970Q	26970	Missense	proximal	-1	no	9.189	9.184	EPSD	ICGC	7.092	Down-regulation
AGC_PKG_PRKG1_ST	Q8WZ42	TTN	Q13976	PRKG1	S26971	R26968S	26968	Missense	distal	-3	no	9.189	3.701	EPSD	ICGC;COSMIC	7.092	Loss
AGC_PKG_PRKG1_ST	Q8WZ42	TTN	Q13976	PRKG1	S26971	R26975W	26975	Missense	distal	4	no	9.189	9.407	EPSD	ICGC;COSMIC	7.092	Up-regulation
AGC_PKG_PRKG1_ST	Q8WZ42	TTN	Q13976	PRKG1	S27368	E27366D	27366	Missense	proximal	-2	no	7.477	6.574	EPSD	ICGC;COSMIC	7.092	Loss
AGC_PKG_PRKG1_ST	Q8WZ42	TTN	Q13976	PRKG1	S27368	F27372L	27372	Missense	distal	4	no	7.477	7.600	EPSD	ICGC;COSMIC	7.092	Up-regulation
AGC_PKG_PRKG1_ST	Q8WZ42	TTN	Q13976	PRKG1	S27368	R27365K	27365	Missense	distal	-3	no	7.477	5.119	EPSD	ICGC;COSMIC	7.092	Loss
AGC_PKG_PRKG1_ST	Q8WZ42	TTN	Q13976	PRKG1	S27368	R27373Q	27373	Missense	distal	5	no	7.477	7.453	EPSD	ICGC;COSMIC;CCLE	7.092	Down-regulation
AGC_PKG_PRKG1_ST	Q8WZ42	TTN	Q13976	PRKG1	S27419	D27424G	27424	Missense	distal	5	no	10.535	10.549	EPSD	ICGC	7.092	Up-regulation
AGC_PKG_PRKG1_ST	Q8WZ42	TTN	Q13976	PRKG1	S27419	R27416G	27416	Missense	distal	-3	no	10.535	5.944	EPSD	ICGC	7.092	Loss
AGC_PKG_PRKG1_ST	Q8WZ42	TTN	Q13976	PRKG1	S27419	R27416S	27416	Missense	distal	-3	no	10.535	5.046	EPSD	ICGC;COSMIC	7.092	Loss
AGC_PKG_PRKG1_ST	Q8WZ42	TTN	Q13976	PRKG1	S27540	T27545N	27545	Missense	distal	5	no	7.690	7.661	EPSD	ICGC	7.092	Down-regulation
AGC_PKG_PRKG1_ST	Q8WZ42	TTN	Q13976	PRKG1	S27622	E27619K	27619	Missense	distal	-3	no	3.208	7.791	EPSD	ICGC;COSMIC	7.092	Gain
AGC_PKG_PRKG1_ST	Q8WZ42	TTN	Q13976	PRKG1	S27867	G27868K	27868	Missense	proximal	1	no	7.364	7.599	EPSD	ICGC	7.092	Up-regulation
AGC_PKG_PRKG1_ST	Q8WZ42	TTN	Q13976	PRKG1	S27867	R27864H	27864	Missense	distal	-3	no	7.364	1.297	EPSD	ICGC;COSMIC	7.092	Loss
AGC_PKG_PRKG1_ST	Q8WZ42	TTN	Q13976	PRKG1	S27867	Y27870F	27870	Missense	distal	3	no	7.364	7.356	EPSD	ICGC;COSMIC	7.092	Down-regulation
AGC_PKG_PRKG1_ST	Q8WZ42	TTN	Q13976	PRKG1	S27867	D27863N	27863	Missense	distal	-4	no	7.364	7.633	EPSD	ICGC;COSMIC	7.092	Up-regulation
AGC_PKG_PRKG1_ST	Q8WZ42	TTN	Q13976	PRKG1	S27882	A27877V	27877	Missense	distal	-5	no	7.671	7.796	EPSD	ICGC;COSMIC	7.092	Up-regulation
AGC_PKG_PRKG1_ST	Q8WZ42	TTN	Q13976	PRKG1	S27882	R27886I	27886	Missense	distal	4	no	7.671	7.928	EPSD	ICGC;COSMIC	7.092	Up-regulation
AGC_PKG_PRKG1_ST	Q8WZ42	TTN	Q13976	PRKG1	T28055	V28054I	28054	Missense	proximal	-1	no	7.562	7.475	EPSD	ICGC;COSMIC	7.092	Down-regulation
AGC_PKG_PRKG1_ST	Q8WZ42	TTN	Q13976	PRKG1	T28055	R28048H	28048	Missense	distal	-7	no	7.562	6.389	EPSD	ICGC;COSMIC	7.092	Loss
AGC_PKG_PRKG1_ST	Q8WZ42	TTN	Q13976	PRKG1	T28055	L28057F	28057	Missense	proximal	2	no	7.562	7.628	EPSD	ICGC	7.092	Up-regulation
AGC_PKG_PRKG1_ST	Q8WZ42	TTN	Q13976	PRKG1	T28055	R28048S	28048	Missense	distal	-7	no	7.562	6.930	EPSD	ICGC	7.092	Loss
AGC_PKG_PRKG1_ST	Q8WZ42	TTN	Q13976	PRKG1	T28055	R28051T	28051	Missense	distal	-4	no	7.562	6.974	EPSD	ICGC;COSMIC	7.092	Loss
AGC_PKG_PRKG1_ST	Q8WZ42	TTN	Q13976	PRKG1	T28055	D28049E	28049	Missense	distal	-6	no	7.562	7.706	EPSD	ICGC;COSMIC	7.092	Up-regulation
AGC_PKG_PRKG1_ST	Q8WZ42	TTN	Q13976	PRKG1	T28055	R28048C	28048	Missense	distal	-7	no	7.562	6.134	EPSD	ICGC;COSMIC	7.092	Loss
AGC_PKG_PRKG1_ST	Q8WZ42	TTN	Q13976	PRKG1	T28338	R28337I	28337	Missense	proximal	-1	no	7.446	7.144	EPSD	ICGC;COSMIC	7.092	Down-regulation
AGC_PKG_PRKG1_ST	Q8WZ42	TTN	Q13976	PRKG1	T28338	V28342M	28342	Missense	distal	4	no	7.446	7.328	EPSD	ICGC	7.092	Down-regulation
AGC_PKG_PRKG1_ST	Q8WZ42	TTN	Q13976	PRKG1	T28338	A28334G	28334	Missense	distal	-4	no	7.446	7.237	EPSD	ICGC;COSMIC	7.092	Down-regulation
AGC_PKG_PRKG1_ST	Q8WZ42	TTN	Q13976	PRKG1	T28338	A28334T	28334	Missense	distal	-4	no	7.446	7.332	EPSD	ICGC;COSMIC	7.092	Down-regulation
AGC_PKG_PRKG1_ST	Q8WZ42	TTN	Q13976	PRKG1	T28338	K28331T	28331	Missense	distal	-7	no	7.446	7.067	EPSD	ICGC;COSMIC	7.092	Loss
AGC_PKG_PRKG1_ST	Q8WZ42	TTN	Q13976	PRKG1	T28338	K28345T	28345	Missense	distal	7	no	7.446	7.439	EPSD	ICGC;COSMIC	7.092	Down-regulation
AGC_PKG_PRKG1_ST	Q8WZ42	TTN	Q13976	PRKG1	S28340	R28337I	28337	Missense	distal	-3	no	9.517	1.010	EPSD	ICGC;COSMIC	7.092	Loss
AGC_PKG_PRKG1_ST	Q8WZ42	TTN	Q13976	PRKG1	S28340	V28342M	28342	Missense	proximal	2	no	9.517	9.585	EPSD	ICGC	7.092	Up-regulation
AGC_PKG_PRKG1_ST	Q8WZ42	TTN	Q13976	PRKG1	S28340	A28334G	28334	Missense	distal	-6	no	9.517	9.343	EPSD	ICGC;COSMIC	7.092	Down-regulation
AGC_PKG_PRKG1_ST	Q8WZ42	TTN	Q13976	PRKG1	S28340	A28334T	28334	Missense	distal	-6	no	9.517	9.477	EPSD	ICGC;COSMIC	7.092	Down-regulation
AGC_PKG_PRKG1_ST	Q8WZ42	TTN	Q13976	PRKG1	S28340	K28345T	28345	Missense	distal	5	no	9.517	9.508	EPSD	ICGC;COSMIC	7.092	Down-regulation
AGC_PKG_PRKG1_ST	Q8WZ42	TTN	Q13976	PRKG1	T28435	E28433K	28433	Missense	proximal	-2	no	3.578	7.101	EPSD	ICGC;COSMIC	7.092	Gain
AGC_PKG_PRKG1_ST	Q8WZ42	TTN	Q13976	PRKG1	S28521	P28520T	28520	Missense	proximal	-1	no	7.355	7.457	EPSD	ICGC;COSMIC	7.092	Up-regulation
AGC_PKG_PRKG1_ST	Q8WZ42	TTN	Q13976	PRKG1	S28521	P28518R	28518	Missense	distal	-3	no	7.355	12.257	EPSD	ICGC;COSMIC	7.092	Up-regulation
AGC_PKG_PRKG1_ST	Q8WZ42	TTN	Q13976	PRKG1	S28521	S28521P	28521	Missense	central	0	yes	7.355	0.000	EPSD	ICGC	7.092	Loss
AGC_PKG_PRKG1_ST	Q8WZ42	TTN	Q13976	PRKG1	S28627	E28625K	28625	Missense	proximal	-2	no	8.326	11.849	EPSD	ICGC;COSMIC	7.092	Up-regulation
AGC_PKG_PRKG1_ST	Q8WZ42	TTN	Q13976	PRKG1	S28627	E28622K	28622	Missense	distal	-5	no	8.326	8.146	EPSD	ICGC;COSMIC	7.092	Down-regulation
AGC_PKG_PRKG1_ST	Q8WZ42	TTN	Q13976	PRKG1	S28627	S28627L	28627	Missense	central	0	yes	8.326	0.000	EPSD	ICGC;COSMIC	7.092	Loss
AGC_PKG_PRKG1_ST	Q8WZ42	TTN	Q13976	PRKG1	S28627	E28622D	28622	Missense	distal	-5	no	8.326	8.368	EPSD	ICGC;COSMIC	7.092	Up-regulation
AGC_PKG_PRKG1_ST	Q8WZ42	TTN	Q13976	PRKG1	S28627	T28629N	28629	Missense	proximal	2	no	8.326	8.295	EPSD	ICGC;COSMIC	7.092	Down-regulation
AGC_PKG_PRKG1_ST	Q8WZ42	TTN	Q13976	PRKG1	S28627	R28624W	28624	Missense	distal	-3	no	8.326	0.654	EPSD	ICGC;COSMIC	7.092	Loss
AGC_PKG_PRKG1_ST	Q8WZ42	TTN	Q13976	PRKG1	S28627	T28626I	28626	Missense	proximal	-1	no	8.326	8.127	EPSD	ICGC;COSMIC	7.092	Down-regulation
AGC_PKG_PRKG1_ST	Q8WZ42	TTN	Q13976	PRKG1	S28627	K28623E	28623	Missense	distal	-4	no	8.326	7.666	EPSD	ICGC;COSMIC	7.092	Down-regulation
AGC_PKG_PRKG1_ST	Q8WZ42	TTN	Q13976	PRKG1	S28667	G28665R	28665	Missense	proximal	-2	no	5.472	8.960	EPSD	ICGC;COSMIC	7.092	Gain
AGC_PKG_PRKG1_ST	Q8WZ42	TTN	Q13976	PRKG1	S28763	E28761K	28761	Missense	proximal	-2	no	5.319	8.842	EPSD	ICGC;COSMIC	7.092	Gain
AGC_PKG_PRKG1_ST	Q8WZ42	TTN	Q13976	PRKG1	S28770	S28767R	28767	Missense	distal	-3	no	4.730	10.219	EPSD	ICGC;COSMIC	7.092	Gain
AGC_PKG_PRKG1_ST	Q8WZ42	TTN	Q13976	PRKG1	S29104	A29100E	29100	Missense	distal	-4	no	7.836	7.345	EPSD	ICGC;COSMIC	7.092	Down-regulation
AGC_PKG_PRKG1_ST	Q8WZ42	TTN	Q13976	PRKG1	T29123	K29127N	29127	Missense	distal	4	no	7.408	7.484	EPSD	ICGC;COSMIC	7.092	Up-regulation
AGC_PKG_PRKG1_ST	Q8WZ42	TTN	Q13976	PRKG1	T29123	I29129M	29129	Missense	distal	6	no	7.408	7.129	EPSD	ICGC;COSMIC	7.092	Down-regulation
AGC_PKG_PRKG1_ST	Q8WZ42	TTN	Q13976	PRKG1	T29123	K29120N	29120	Missense	distal	-3	no	7.408	2.861	EPSD	ICGC;COSMIC	7.092	Loss
AGC_PKG_PRKG1_ST	Q8WZ42	TTN	Q13976	PRKG1	T29123	S29122R	29122	Missense	proximal	-1	no	7.408	7.509	EPSD	ICGC	7.092	Up-regulation
AGC_PKG_PRKG1_ST	Q8WZ42	TTN	Q13976	PRKG1	T29123	E29116K	29116	Missense	distal	-7	no	7.408	8.409	EPSD	ICGC;COSMIC	7.092	Up-regulation
AGC_PKG_PRKG1_ST	Q8WZ42	TTN	Q13976	PRKG1	T29123	E29119K	29119	Missense	distal	-4	no	7.408	8.068	EPSD	ICGC;COSMIC	7.092	Up-regulation
AGC_PKG_PRKG1_ST	Q8WZ42	TTN	Q13976	PRKG1	S29135	I29129M	29129	Missense	distal	-6	no	9.287	9.808	EPSD	ICGC;COSMIC	7.092	Up-regulation
AGC_PKG_PRKG1_ST	Q8WZ42	TTN	Q13976	PRKG1	S29135	K29131R	29131	Missense	distal	-4	no	9.287	9.591	EPSD	ICGC;COSMIC	7.092	Up-regulation
AGC_PKG_PRKG1_ST	Q8WZ42	TTN	Q13976	PRKG1	S29135	R29132Q	29132	Missense	distal	-3	no	9.287	5.452	EPSD	ICGC;COSMIC	7.092	Loss
AGC_PKG_PRKG1_ST	Q8WZ42	TTN	Q13976	PRKG1	S29135	P29133S	29133	Missense	proximal	-2	no	9.287	9.638	EPSD	ICGC	7.092	Up-regulation
AGC_PKG_PRKG1_ST	Q8WZ42	TTN	Q13976	PRKG1	T29241	V29236M	29236	Missense	distal	-5	no	7.593	7.490	EPSD	ICGC;COSMIC	7.092	Down-regulation
AGC_PKG_PRKG1_ST	Q8WZ42	TTN	Q13976	PRKG1	T29241	V29236A	29236	Missense	distal	-5	no	7.593	7.469	EPSD	ICGC	7.092	Down-regulation
AGC_PKG_PRKG1_ST	Q8WZ42	TTN	Q13976	PRKG1	T29241	C29235F	29235	Missense	distal	-6	no	7.593	7.668	EPSD	ICGC	7.092	Up-regulation
AGC_PKG_PRKG1_ST	Q8WZ42	TTN	Q13976	PRKG1	S29421	R29419H	29419	Missense	proximal	-2	no	10.167	5.909	EPSD	ICGC;COSMIC	7.092	Loss
AGC_PKG_PRKG1_ST	Q8WZ42	TTN	Q13976	PRKG1	S29421	S29426N	29426	Missense	distal	5	no	10.167	10.133	EPSD	ICGC;COSMIC	7.092	Down-regulation
AGC_PKG_PRKG1_ST	Q8WZ42	TTN	Q13976	PRKG1	S29421	A29417S	29417	Missense	distal	-4	no	10.167	10.171	EPSD	ICGC;COSMIC	7.092	Up-regulation
AGC_PKG_PRKG1_ST	Q8WZ42	TTN	Q13976	PRKG1	S29421	R29420H	29420	Missense	proximal	-1	no	10.167	10.019	EPSD	ICGC;COSMIC	7.092	Down-regulation
AGC_PKG_PRKG1_ST	Q8WZ42	TTN	Q13976	PRKG1	S29421	R29420S	29420	Missense	proximal	-1	no	10.167	10.065	EPSD	ICGC;COSMIC	7.092	Down-regulation
AGC_PKG_PRKG1_ST	Q8WZ42	TTN	Q13976	PRKG1	S29421	R29415Q	29415	Missense	distal	-6	no	10.167	9.870	EPSD	ICGC;COSMIC	7.092	Down-regulation
AGC_PKG_PRKG1_ST	Q8WZ42	TTN	Q13976	PRKG1	S29516	D29517H	29517	Missense	proximal	1	no	8.744	8.918	EPSD	ICGC;COSMIC	7.092	Up-regulation
AGC_PKG_PRKG1_ST	Q8WZ42	TTN	Q13976	PRKG1	S29516	L29509F	29509	Missense	distal	-7	no	8.744	9.482	EPSD	ICGC	7.092	Up-regulation
AGC_PKG_PRKG1_ST	Q8WZ42	TTN	Q13976	PRKG1	S29561	E29558K	29558	Missense	distal	-3	no	3.870	8.453	EPSD	ICGC;COSMIC	7.092	Gain
AGC_PKG_PRKG1_ST	Q8WZ42	TTN	Q13976	PRKG1	S29637	D29636Y	29636	Missense	proximal	-1	no	8.108	8.178	EPSD	ICGC;COSMIC	7.092	Up-regulation
AGC_PKG_PRKG1_ST	Q8WZ42	TTN	Q13976	PRKG1	S29642	D29636Y	29636	Missense	distal	-6	no	10.753	10.882	EPSD	ICGC;COSMIC	7.092	Up-regulation
AGC_PKG_PRKG1_ST	Q8WZ42	TTN	Q13976	PRKG1	S29659	G29654C	29654	Missense	distal	-5	no	8.841	8.871	EPSD	ICGC;COSMIC	7.092	Up-regulation
AGC_PKG_PRKG1_ST	Q8WZ42	TTN	Q13976	PRKG1	S29710	S29710P	29710	Missense	central	0	yes	9.960	0.000	EPSD	ICGC;COSMIC	7.092	Loss
AGC_PKG_PRKG1_ST	Q8WZ42	TTN	Q13976	PRKG1	S29710	R29708H	29708	Missense	proximal	-2	no	9.960	5.702	EPSD	ICGC;COSMIC	7.092	Loss
AGC_PKG_PRKG1_ST	Q8WZ42	TTN	Q13976	PRKG1	S29710	S29710L	29710	Missense	central	0	yes	9.960	0.000	EPSD	ICGC;COSMIC	7.092	Loss
AGC_PKG_PRKG1_ST	Q8WZ42	TTN	Q13976	PRKG1	S29780	H29778R	29778	Missense	proximal	-2	no	3.893	8.150	EPSD	ICGC;COSMIC	7.092	Gain
AGC_PKG_PRKG1_ST	Q8WZ42	TTN	Q13976	PRKG1	S29990	I29986N	29986	Missense	distal	-4	no	7.706	8.173	EPSD	ICGC;COSMIC	7.092	Up-regulation
AGC_PKG_PRKG1_ST	Q8WZ42	TTN	Q13976	PRKG1	S29990	A29996D	29996	Missense	distal	6	no	7.706	7.907	EPSD	ICGC;COSMIC	7.092	Up-regulation
AGC_PKG_PRKG1_ST	Q8WZ42	TTN	Q13976	PRKG1	S29990	D29995N	29995	Missense	distal	5	no	7.706	7.742	EPSD	ICGC;COSMIC	7.092	Up-regulation
AGC_PKG_PRKG1_ST	Q8WZ42	TTN	Q13976	PRKG1	S29990	L29983M	29983	Missense	distal	-7	no	7.706	8.833	EPSD	ICGC;COSMIC	7.092	Up-regulation
AGC_PKG_PRKG1_ST	Q8WZ42	TTN	Q13976	PRKG1	S30022	E30019K	30019	Missense	distal	-3	no	2.556	7.139	EPSD	ICGC;COSMIC	7.092	Gain
AGC_PKG_PRKG1_ST	Q8WZ42	TTN	Q13976	PRKG1	T30046	S30042G	30042	Missense	distal	-4	no	7.771	7.558	EPSD	ICGC;COSMIC	7.092	Down-regulation
AGC_PKG_PRKG1_ST	Q8WZ42	TTN	Q13976	PRKG1	T30046	D30041H	30041	Missense	distal	-5	no	7.771	7.657	EPSD	ICGC;COSMIC	7.092	Down-regulation
AGC_PKG_PRKG1_ST	Q8WZ42	TTN	Q13976	PRKG1	T30046	Y30045H	30045	Missense	proximal	-1	no	7.771	7.816	EPSD	ICGC;COSMIC	7.092	Up-regulation
AGC_PKG_PRKG1_ST	Q8WZ42	TTN	Q13976	PRKG1	T30046	A30052D	30052	Missense	distal	6	no	7.771	7.972	EPSD	ICGC	7.092	Up-regulation
AGC_PKG_PRKG1_ST	Q8WZ42	TTN	Q13976	PRKG1	T30080	S30077R	30077	Missense	distal	-3	no	4.562	10.051	EPSD	ICGC;COSMIC	7.092	Gain
AGC_PKG_PRKG1_ST	Q8WZ42	TTN	Q13976	PRKG1	S30163	N30162H	30162	Missense	proximal	-1	no	7.845	7.882	EPSD	ICGC;COSMIC	7.092	Up-regulation
AGC_PKG_PRKG1_ST	Q8WZ42	TTN	Q13976	PRKG1	S30266	R30263K	30263	Missense	distal	-3	no	8.429	6.071	EPSD	ICGC;COSMIC	7.092	Loss
AGC_PKG_PRKG1_ST	Q8WZ42	TTN	Q13976	PRKG1	S30266	P30265T	30265	Missense	proximal	-1	no	8.429	8.530	EPSD	ICGC;COSMIC	7.092	Up-regulation
AGC_PKG_PRKG1_ST	Q8WZ42	TTN	Q13976	PRKG1	S30266	P30271T	30271	Missense	distal	5	no	8.429	8.496	EPSD	ICGC	7.092	Up-regulation
AGC_PKG_PRKG1_ST	Q8WZ42	TTN	Q13976	PRKG1	S30266	T30268I	30268	Missense	proximal	2	no	8.429	8.333	EPSD	ICGC	7.092	Down-regulation
AGC_PKG_PRKG1_ST	Q8WZ42	TTN	Q13976	PRKG1	T30327	I30324K	30324	Missense	distal	-3	no	3.248	9.396	EPSD	ICGC;COSMIC	7.092	Gain
AGC_PKG_PRKG1_ST	Q8WZ42	TTN	Q13976	PRKG1	S30356	S30353R	30353	Missense	distal	-3	no	3.704	9.192	EPSD	ICGC;COSMIC	7.092	Gain
AGC_PKG_PRKG1_ST	Q8WZ42	TTN	Q13976	PRKG1	S30356	E30354K	30354	Missense	proximal	-2	no	3.704	7.226	EPSD	ICGC;COSMIC	7.092	Gain
AGC_PKG_PRKG1_ST	Q8WZ42	TTN	Q13976	PRKG1	S30454	A30455T	30455	Missense	proximal	1	no	7.944	7.907	EPSD	ICGC;COSMIC	7.092	Down-regulation
AGC_PKG_PRKG1_ST	Q8WZ42	TTN	Q13976	PRKG1	S30454	V30459A	30459	Missense	distal	5	no	7.944	7.994	EPSD	ICGC;COSMIC	7.092	Up-regulation
AGC_PKG_PRKG1_ST	Q8WZ42	TTN	Q13976	PRKG1	S30454	N30448I	30448	Missense	distal	-6	no	7.944	7.590	EPSD	ICGC;COSMIC	7.092	Down-regulation
AGC_PKG_PRKG1_ST	Q8WZ42	TTN	Q13976	PRKG1	S30454	G30451S	30451	Missense	distal	-3	no	7.944	7.046	EPSD	ICGC;COSMIC	7.092	Loss
AGC_PKG_PRKG1_ST	Q8WZ42	TTN	Q13976	PRKG1	S30454	T30456A	30456	Missense	proximal	2	no	7.944	7.952	EPSD	ICGC;COSMIC	7.092	Up-regulation
AGC_PKG_PRKG1_ST	Q8WZ42	TTN	Q13976	PRKG1	T30456	Y30462D	30462	Missense	distal	6	no	7.502	7.541	EPSD	ICGC;COSMIC	7.092	Up-regulation
AGC_PKG_PRKG1_ST	Q8WZ42	TTN	Q13976	PRKG1	T30456	A30455T	30455	Missense	proximal	-1	no	7.502	7.506	EPSD	ICGC;COSMIC	7.092	Up-regulation
AGC_PKG_PRKG1_ST	Q8WZ42	TTN	Q13976	PRKG1	T30456	V30459A	30459	Missense	distal	3	no	7.502	7.300	EPSD	ICGC;COSMIC	7.092	Down-regulation
AGC_PKG_PRKG1_ST	Q8WZ42	TTN	Q13976	PRKG1	T30456	G30451S	30451	Missense	distal	-5	no	7.502	7.415	EPSD	ICGC;COSMIC	7.092	Down-regulation
AGC_PKG_PRKG1_ST	Q8WZ42	TTN	Q13976	PRKG1	T30456	T30456A	30456	Missense	central	0	yes	7.502	0.000	EPSD	ICGC;COSMIC	7.092	Loss
AGC_PKG_PRKG1_ST	Q8WZ42	TTN	Q13976	PRKG1	T30456	D30463Y	30463	Missense	distal	7	no	7.502	7.520	EPSD	ICGC;COSMIC	7.092	Up-regulation
AGC_PKG_PRKG1_ST	Q8WZ42	TTN	Q13976	PRKG1	S30519	R30524S	30524	Missense	distal	5	no	8.015	7.993	EPSD	ICGC;COSMIC	7.092	Down-regulation
AGC_PKG_PRKG1_ST	Q8WZ42	TTN	Q13976	PRKG1	S30519	L30522H	30522	Missense	distal	3	no	8.015	7.737	EPSD	ICGC;COSMIC	7.092	Down-regulation
AGC_PKG_PRKG1_ST	Q8WZ42	TTN	Q13976	PRKG1	T30650	V30654M	30654	Missense	distal	4	no	7.181	7.063	EPSD	ICGC;COSMIC	7.092	Loss
AGC_PKG_PRKG1_ST	Q8WZ42	TTN	Q13976	PRKG1	T30650	T30650N	30650	Missense	central	0	yes	7.181	0.000	EPSD	ICGC	7.092	Loss
AGC_PKG_PRKG1_ST	Q8WZ42	TTN	Q13976	PRKG1	T30650	T30650I	30650	Missense	central	0	yes	7.181	0.000	EPSD	ICGC	7.092	Loss
AGC_PKG_PRKG1_ST	Q8WZ42	TTN	Q13976	PRKG1	T30650	R30648K	30648	Missense	proximal	-2	no	7.181	5.704	EPSD	ICGC;COSMIC	7.092	Loss
AGC_PKG_PRKG1_ST	Q8WZ42	TTN	Q13976	PRKG1	S30920	R30919H	30919	Missense	proximal	-1	no	8.644	8.496	EPSD	ICGC;COSMIC	7.092	Down-regulation
AGC_PKG_PRKG1_ST	Q8WZ42	TTN	Q13976	PRKG1	S30920	R30917Q	30917	Missense	distal	-3	no	8.644	4.809	EPSD	ICGC	7.092	Loss
AGC_PKG_PRKG1_ST	Q8WZ42	TTN	Q13976	PRKG1	S30920	T30916A	30916	Missense	distal	-4	no	8.644	8.758	EPSD	ICGC;COSMIC	7.092	Up-regulation
AGC_PKG_PRKG1_ST	Q8WZ42	TTN	Q13976	PRKG1	S30941	I30936F	30936	Missense	distal	-5	no	7.539	7.418	EPSD	ICGC;COSMIC	7.092	Down-regulation
AGC_PKG_PRKG1_ST	Q8WZ42	TTN	Q13976	PRKG1	S30941	T30934I	30934	Missense	distal	-7	no	7.539	6.374	EPSD	ICGC;COSMIC	7.092	Loss
AGC_PKG_PRKG1_ST	Q8WZ42	TTN	Q13976	PRKG1	S31129	A31124E	31124	Missense	distal	-5	no	9.849	9.984	EPSD	ICGC	7.092	Up-regulation
AGC_PKG_PRKG1_ST	Q8WZ42	TTN	Q13976	PRKG1	S31129	D31125E	31125	Missense	distal	-4	no	9.849	9.995	EPSD	ICGC;COSMIC	7.092	Up-regulation
AGC_PKG_PRKG1_ST	Q8WZ42	TTN	Q13976	PRKG1	S31129	D31133Y	31133	Missense	distal	4	no	9.849	9.865	EPSD	ICGC;COSMIC	7.092	Up-regulation
AGC_PKG_PRKG1_ST	Q8WZ42	TTN	Q13976	PRKG1	S31129	D31133N	31133	Missense	distal	4	no	9.849	9.796	EPSD	ICGC;COSMIC	7.092	Down-regulation
AGC_PKG_PRKG1_ST	Q8WZ42	TTN	Q13976	PRKG1	S31213	D31206H	31206	Missense	distal	-7	no	8.414	8.936	EPSD	ICGC;COSMIC	7.092	Up-regulation
AGC_PKG_PRKG1_ST	Q8WZ42	TTN	Q13976	PRKG1	S31213	G31211S	31211	Missense	proximal	-2	no	8.414	8.494	EPSD	ICGC;COSMIC	7.092	Up-regulation
AGC_PKG_PRKG1_ST	Q8WZ42	TTN	Q13976	PRKG1	S31213	R31210Q	31210	Missense	distal	-3	no	8.414	4.580	EPSD	ICGC;COSMIC	7.092	Loss
AGC_PKG_PRKG1_ST	Q8WZ42	TTN	Q13976	PRKG1	S31213	D31206N	31206	Missense	distal	-7	no	8.414	8.869	EPSD	ICGC;COSMIC	7.092	Up-regulation
AGC_PKG_PRKG1_ST	Q8WZ42	TTN	Q13976	PRKG1	S31213	L31214M	31214	Missense	proximal	1	no	8.414	8.800	EPSD	ICGC	7.092	Up-regulation
AGC_PKG_PRKG1_ST	Q8WZ42	TTN	Q13976	PRKG1	S31456	G31461V	31461	Missense	distal	5	no	7.451	7.440	EPSD	ICGC;COSMIC	7.092	Down-regulation
AGC_PKG_PRKG1_ST	Q8WZ42	TTN	Q13976	PRKG1	S31509	R31513C	31513	Missense	distal	4	no	7.333	7.492	EPSD	ICGC;COSMIC	7.092	Up-regulation
AGC_PKG_PRKG1_ST	Q8WZ42	TTN	Q13976	PRKG1	S31509	R31513H	31513	Missense	distal	4	no	7.333	7.451	EPSD	ICGC;COSMIC;CCLE	7.092	Up-regulation
AGC_PKG_PRKG1_ST	Q8WZ42	TTN	Q13976	PRKG1	S31509	R31504L	31504	Missense	distal	-5	no	7.333	7.709	EPSD	ICGC;COSMIC	7.092	Up-regulation
AGC_PKG_PRKG1_ST	Q8WZ42	TTN	Q13976	PRKG1	S31509	R31504W	31504	Missense	distal	-5	no	7.333	7.656	EPSD	ICGC;COSMIC	7.092	Up-regulation
AGC_PKG_PRKG1_ST	Q8WZ42	TTN	Q13976	PRKG1	S31509	T31516A	31516	Missense	distal	7	no	7.333	7.322	EPSD	ICGC	7.092	Down-regulation
AGC_PKG_PRKG1_ST	Q8WZ42	TTN	Q13976	PRKG1	S31510	R31513C	31513	Missense	distal	3	no	9.289	9.511	EPSD	ICGC;COSMIC	7.092	Up-regulation
AGC_PKG_PRKG1_ST	Q8WZ42	TTN	Q13976	PRKG1	S31510	R31513H	31513	Missense	distal	3	no	9.289	9.444	EPSD	ICGC;COSMIC;CCLE	7.092	Up-regulation
AGC_PKG_PRKG1_ST	Q8WZ42	TTN	Q13976	PRKG1	S31510	R31504L	31504	Missense	distal	-6	no	9.289	8.365	EPSD	ICGC;COSMIC	7.092	Down-regulation
AGC_PKG_PRKG1_ST	Q8WZ42	TTN	Q13976	PRKG1	S31510	R31504W	31504	Missense	distal	-6	no	9.289	8.460	EPSD	ICGC;COSMIC	7.092	Down-regulation
AGC_PKG_PRKG1_ST	Q8WZ42	TTN	Q13976	PRKG1	S31510	T31516A	31516	Missense	distal	6	no	9.289	9.280	EPSD	ICGC	7.092	Down-regulation
AGC_PKG_PRKG1_ST	Q8WZ42	TTN	Q13976	PRKG1	T31516	E31522K	31522	Missense	distal	6	no	7.639	7.422	EPSD	ICGC;COSMIC	7.092	Down-regulation
AGC_PKG_PRKG1_ST	Q8WZ42	TTN	Q13976	PRKG1	T31516	R31513C	31513	Missense	distal	-3	no	7.639	0.617	EPSD	ICGC;COSMIC	7.092	Loss
AGC_PKG_PRKG1_ST	Q8WZ42	TTN	Q13976	PRKG1	T31516	R31513H	31513	Missense	distal	-3	no	7.639	1.572	EPSD	ICGC;COSMIC;CCLE	7.092	Loss
AGC_PKG_PRKG1_ST	Q8WZ42	TTN	Q13976	PRKG1	T31516	T31516A	31516	Missense	central	0	yes	7.639	0.000	EPSD	ICGC	7.092	Loss
AGC_PKG_PRKG1_ST	Q8WZ42	TTN	Q13976	PRKG1	S31870	A31872V	31872	Missense	proximal	2	no	8.970	8.885	EPSD	ICGC;COSMIC	7.092	Down-regulation
AGC_PKG_PRKG1_ST	Q8WZ42	TTN	Q13976	PRKG1	S31870	L31874F	31874	Missense	distal	4	no	8.970	8.847	EPSD	ICGC;COSMIC	7.092	Down-regulation
AGC_PKG_PRKG1_ST	Q8WZ42	TTN	Q13976	PRKG1	S31870	L31864P	31864	Missense	distal	-6	no	8.970	9.280	EPSD	ICGC;COSMIC	7.092	Up-regulation
AGC_PKG_PRKG1_ST	Q8WZ42	TTN	Q13976	PRKG1	T32010	R32007T	32007	Missense	distal	-3	no	8.071	2.906	EPSD	ICGC;COSMIC	7.092	Loss
AGC_PKG_PRKG1_ST	Q8WZ42	TTN	Q13976	PRKG1	T32010	I32004T	32004	Missense	distal	-6	no	8.071	8.623	EPSD	ICGC;COSMIC	7.092	Up-regulation
AGC_PKG_PRKG1_ST	Q8WZ42	TTN	Q13976	PRKG1	S32064	E32071A	32071	Missense	distal	7	no	7.111	7.178	EPSD	ICGC;COSMIC	7.092	Up-regulation
AGC_PKG_PRKG1_ST	Q8WZ42	TTN	Q13976	PRKG1	S32064	L32067V	32067	Missense	distal	3	no	7.111	6.969	EPSD	ICGC;COSMIC	7.092	Loss
AGC_PKG_PRKG1_ST	Q8WZ42	TTN	Q13976	PRKG1	S32064	V32060A	32060	Missense	distal	-4	no	7.111	7.638	EPSD	ICGC;COSMIC	7.092	Up-regulation
AGC_PKG_PRKG1_ST	Q8WZ42	TTN	Q13976	PRKG1	T32104	R32097H	32097	Missense	distal	-7	no	8.183	7.010	EPSD	ICGC;COSMIC	7.092	Loss
AGC_PKG_PRKG1_ST	Q8WZ42	TTN	Q13976	PRKG1	S32133	S32130R	32130	Missense	distal	-3	no	5.248	10.737	EPSD	ICGC;COSMIC	7.092	Gain
AGC_PKG_PRKG1_ST	Q8WZ42	TTN	Q13976	PRKG1	S32162	V32161F	32161	Missense	proximal	-1	no	7.891	7.912	EPSD	ICGC;COSMIC	7.092	Up-regulation
AGC_PKG_PRKG1_ST	Q8WZ42	TTN	Q13976	PRKG1	S32162	E32157K	32157	Missense	distal	-5	no	7.891	7.710	EPSD	ICGC;COSMIC	7.092	Down-regulation
AGC_PKG_PRKG1_ST	Q8WZ42	TTN	Q13976	PRKG1	S32224	E32222K	32222	Missense	proximal	-2	no	4.167	7.689	EPSD	ICGC;COSMIC	7.092	Gain
AGC_PKG_PRKG1_ST	Q8WZ42	TTN	Q13976	PRKG1	S32311	T32308S	32308	Missense	distal	-3	no	8.049	7.726	EPSD	ICGC;COSMIC	7.092	Down-regulation
AGC_PKG_PRKG1_ST	Q8WZ42	TTN	Q13976	PRKG1	S32312	T32308S	32308	Missense	distal	-4	no	13.055	13.174	EPSD	ICGC;COSMIC	7.092	Up-regulation
AGC_PKG_PRKG1_ST	Q8WZ42	TTN	Q13976	PRKG1	T32313	T32308S	32308	Missense	distal	-5	no	9.845	9.836	EPSD	ICGC;COSMIC	7.092	Down-regulation
AGC_PKG_PRKG1_ST	Q8WZ42	TTN	Q13976	PRKG1	S32424	W32431R	32431	Missense	distal	7	no	8.046	8.200	EPSD	ICGC;COSMIC	7.092	Up-regulation
AGC_PKG_PRKG1_ST	Q8WZ42	TTN	Q13976	PRKG1	S32424	S32424L	32424	Missense	central	0	yes	8.046	0.000	EPSD	ICGC;COSMIC	7.092	Loss
AGC_PKG_PRKG1_ST	Q8WZ42	TTN	Q13976	PRKG1	S32424	R32420S	32420	Missense	distal	-4	no	8.046	7.576	EPSD	ICGC;COSMIC	7.092	Down-regulation
AGC_PKG_PRKG1_ST	Q8WZ42	TTN	Q13976	PRKG1	S32424	R32417K	32417	Missense	distal	-7	no	8.046	7.580	EPSD	ICGC;COSMIC	7.092	Down-regulation
AGC_PKG_PRKG1_ST	Q8WZ42	TTN	Q13976	PRKG1	S32424	Q32428E	32428	Missense	distal	4	no	8.046	8.142	EPSD	ICGC;COSMIC	7.092	Up-regulation
AGC_PKG_PRKG1_ST	Q8WZ42	TTN	Q13976	PRKG1	S32424	M32421T	32421	Missense	distal	-3	no	8.046	8.184	EPSD	ICGC;COSMIC	7.092	Up-regulation
AGC_PKG_PRKG1_ST	Q8WZ42	TTN	Q13976	PRKG1	S32440	E32437V	32437	Missense	distal	-3	no	6.290	7.550	EPSD	ICGC;COSMIC	7.092	Gain
AGC_PKG_PRKG1_ST	Q8WZ42	TTN	Q13976	PRKG1	S32491	E32493V	32493	Missense	proximal	2	no	7.500	7.469	EPSD	ICGC;COSMIC	7.092	Down-regulation
AGC_PKG_PRKG1_ST	Q8WZ42	TTN	Q13976	PRKG1	S32491	E32493K	32493	Missense	proximal	2	no	7.500	7.551	EPSD	ICGC;COSMIC	7.092	Up-regulation
AGC_PKG_PRKG1_ST	Q8WZ42	TTN	Q13976	PRKG1	S32491	A32485D	32485	Missense	distal	-6	no	7.500	7.052	EPSD	ICGC	7.092	Loss
AGC_PKG_PRKG1_ST	Q8WZ42	TTN	Q13976	PRKG1	S32491	S32491F	32491	Missense	central	0	yes	7.500	0.000	EPSD	ICGC	7.092	Loss
AGC_PKG_PRKG1_ST	Q8WZ42	TTN	Q13976	PRKG1	T32607	R32605C	32605	Missense	proximal	-2	no	7.297	2.568	EPSD	ICGC;COSMIC	7.092	Loss
AGC_PKG_PRKG1_ST	Q8WZ42	TTN	Q13976	PRKG1	T32607	R32605H	32605	Missense	proximal	-2	no	7.297	3.040	EPSD	ICGC;COSMIC	7.092	Loss
AGC_PKG_PRKG1_ST	Q8WZ42	TTN	Q13976	PRKG1	T32607	R32606K	32606	Missense	proximal	-1	no	7.297	7.238	EPSD	ICGC;COSMIC	7.092	Down-regulation
AGC_PKG_PRKG1_ST	Q8WZ42	TTN	Q13976	PRKG1	T32607	K32601R	32601	Missense	distal	-6	no	7.297	7.462	EPSD	ICGC;COSMIC	7.092	Up-regulation
AGC_PKG_PRKG1_ST	Q8WZ42	TTN	Q13976	PRKG1	T32607	L32612I	32612	Missense	distal	5	no	7.297	7.313	EPSD	ICGC	7.092	Up-regulation
AGC_PKG_PRKG1_ST	Q8WZ42	TTN	Q13976	PRKG1	T32607	E32614K	32614	Missense	distal	7	no	7.297	7.382	EPSD	ICGC	7.092	Up-regulation
AGC_PKG_PRKG1_ST	Q8WZ42	TTN	Q13976	PRKG1	T32607	M32600I	32600	Missense	distal	-7	no	7.297	6.175	EPSD	ICGC	7.092	Loss
AGC_PKG_PRKG1_ST	Q8WZ42	TTN	Q13976	PRKG1	T32607	D32608N	32608	Missense	proximal	1	no	7.297	7.428	EPSD	ICGC;COSMIC	7.092	Up-regulation
AGC_PKG_PRKG1_ST	Q8WZ42	TTN	Q13976	PRKG1	T32607	R32606I	32606	Missense	proximal	-1	no	7.297	6.995	EPSD	ICGC;COSMIC	7.092	Loss
AGC_PKG_PRKG1_ST	Q8WZ42	TTN	Q13976	PRKG1	T32607	K32602N	32602	Missense	distal	-5	no	7.297	7.437	EPSD	ICGC;COSMIC	7.092	Up-regulation
AGC_PKG_PRKG1_ST	Q8WZ42	TTN	Q13976	PRKG1	T32609	R32605C	32605	Missense	distal	-4	no	9.044	8.084	EPSD	ICGC;COSMIC	7.092	Down-regulation
AGC_PKG_PRKG1_ST	Q8WZ42	TTN	Q13976	PRKG1	T32609	R32605H	32605	Missense	distal	-4	no	9.044	8.288	EPSD	ICGC;COSMIC	7.092	Down-regulation
AGC_PKG_PRKG1_ST	Q8WZ42	TTN	Q13976	PRKG1	T32609	R32606K	32606	Missense	distal	-3	no	9.044	6.686	EPSD	ICGC;COSMIC	7.092	Loss
AGC_PKG_PRKG1_ST	Q8WZ42	TTN	Q13976	PRKG1	T32609	L32612I	32612	Missense	distal	3	no	9.044	8.995	EPSD	ICGC	7.092	Down-regulation
AGC_PKG_PRKG1_ST	Q8WZ42	TTN	Q13976	PRKG1	T32609	E32614K	32614	Missense	distal	5	no	9.044	9.107	EPSD	ICGC	7.092	Up-regulation
AGC_PKG_PRKG1_ST	Q8WZ42	TTN	Q13976	PRKG1	T32609	D32608N	32608	Missense	proximal	-1	no	9.044	9.121	EPSD	ICGC;COSMIC	7.092	Up-regulation
AGC_PKG_PRKG1_ST	Q8WZ42	TTN	Q13976	PRKG1	T32609	R32606I	32606	Missense	distal	-3	no	9.044	0.537	EPSD	ICGC;COSMIC	7.092	Loss
AGC_PKG_PRKG1_ST	Q8WZ42	TTN	Q13976	PRKG1	T32609	K32602N	32602	Missense	distal	-7	no	9.044	8.270	EPSD	ICGC;COSMIC	7.092	Down-regulation
AGC_PKG_PRKG1_ST	Q8WZ42	TTN	Q13976	PRKG1	S32803	T32800K	32800	Missense	distal	-3	no	5.828	8.635	EPSD	ICGC	7.092	Gain
AGC_PKG_PRKG1_ST	Q8WZ42	TTN	Q13976	PRKG1	T32911	Q32909R	32909	Missense	proximal	-2	no	4.891	7.856	EPSD	ICGC;COSMIC	7.092	Gain
AGC_PKG_PRKG1_ST	Q8WZ42	TTN	Q13976	PRKG1	T32998	D33002N	33002	Missense	distal	4	no	11.722	11.669	EPSD	ICGC;COSMIC	7.092	Down-regulation
AGC_PKG_PRKG1_ST	Q8WZ42	TTN	Q13976	PRKG1	T32998	R32995H	32995	Missense	distal	-3	no	11.722	5.655	EPSD	ICGC;COSMIC	7.092	Loss
AGC_PKG_PRKG1_ST	Q8WZ42	TTN	Q13976	PRKG1	T32998	Y33003H	33003	Missense	distal	5	no	11.722	11.753	EPSD	ICGC;COSMIC	7.092	Up-regulation
AGC_PKG_PRKG1_ST	Q8WZ42	TTN	Q13976	PRKG1	T32998	R32995S	32995	Missense	distal	-3	no	11.722	6.234	EPSD	ICGC	7.092	Loss
AGC_PKG_PRKG1_ST	Q8WZ42	TTN	Q13976	PRKG1	T32998	D33004E	33004	Missense	distal	6	no	11.722	11.696	EPSD	ICGC	7.092	Down-regulation
AGC_PKG_PRKG1_ST	Q8WZ42	TTN	Q13976	PRKG1	T32998	D33002G	33002	Missense	distal	4	no	11.722	11.699	EPSD	ICGC;COSMIC	7.092	Down-regulation
AGC_PKG_PRKG1_ST	Q8WZ42	TTN	Q13976	PRKG1	T32998	P33001S	33001	Missense	distal	3	no	11.722	11.472	EPSD	ICGC;COSMIC	7.092	Down-regulation
AGC_PKG_PRKG1_ST	Q8WZ42	TTN	Q13976	PRKG1	T32998	R32996Q	32996	Missense	proximal	-2	no	11.722	8.757	EPSD	ICGC;COSMIC	7.092	Down-regulation
AGC_PKG_PRKG1_ST	Q8WZ42	TTN	Q13976	PRKG1	T32998	R32997H	32997	Missense	proximal	-1	no	11.722	11.574	EPSD	ICGC;COSMIC	7.092	Down-regulation
AGC_PKG_PRKG1_ST	Q8WZ42	TTN	Q13976	PRKG1	T32998	R32995C	32995	Missense	distal	-3	no	11.722	4.700	EPSD	ICGC	7.092	Loss
AGC_PKG_PRKG1_ST	Q8WZ42	TTN	Q13976	PRKG1	S33000	D33002N	33002	Missense	proximal	2	no	10.239	10.262	EPSD	ICGC;COSMIC	7.092	Up-regulation
AGC_PKG_PRKG1_ST	Q8WZ42	TTN	Q13976	PRKG1	S33000	R32995H	32995	Missense	distal	-5	no	10.239	10.441	EPSD	ICGC;COSMIC	7.092	Up-regulation
AGC_PKG_PRKG1_ST	Q8WZ42	TTN	Q13976	PRKG1	S33000	Y33003H	33003	Missense	distal	3	no	10.239	10.138	EPSD	ICGC;COSMIC	7.092	Down-regulation
AGC_PKG_PRKG1_ST	Q8WZ42	TTN	Q13976	PRKG1	S33000	R32995S	32995	Missense	distal	-5	no	10.239	10.380	EPSD	ICGC	7.092	Up-regulation
AGC_PKG_PRKG1_ST	Q8WZ42	TTN	Q13976	PRKG1	S33000	D33004E	33004	Missense	distal	4	no	10.239	10.226	EPSD	ICGC	7.092	Down-regulation
AGC_PKG_PRKG1_ST	Q8WZ42	TTN	Q13976	PRKG1	S33000	D33002G	33002	Missense	proximal	2	no	10.239	10.255	EPSD	ICGC;COSMIC	7.092	Up-regulation
AGC_PKG_PRKG1_ST	Q8WZ42	TTN	Q13976	PRKG1	S33000	P33001S	33001	Missense	proximal	1	no	10.239	10.501	EPSD	ICGC;COSMIC	7.092	Up-regulation
AGC_PKG_PRKG1_ST	Q8WZ42	TTN	Q13976	PRKG1	S33000	R32996Q	32996	Missense	distal	-4	no	10.239	9.844	EPSD	ICGC;COSMIC	7.092	Down-regulation
AGC_PKG_PRKG1_ST	Q8WZ42	TTN	Q13976	PRKG1	S33000	R32997H	32997	Missense	distal	-3	no	10.239	4.172	EPSD	ICGC;COSMIC	7.092	Loss
AGC_PKG_PRKG1_ST	Q8WZ42	TTN	Q13976	PRKG1	S33000	R32995C	32995	Missense	distal	-5	no	10.239	10.496	EPSD	ICGC	7.092	Up-regulation
AGC_PKG_PRKG1_ST	Q8WZ42	TTN	Q13976	PRKG1	S33013	I33017V	33017	Missense	distal	4	no	12.058	11.997	EPSD	ICGC	7.092	Down-regulation
AGC_PKG_PRKG1_ST	Q8WZ42	TTN	Q13976	PRKG1	S33013	S33018T	33018	Missense	distal	5	no	12.058	12.053	EPSD	ICGC;COSMIC	7.092	Down-regulation
AGC_PKG_PRKG1_ST	Q8WZ42	TTN	Q13976	PRKG1	S33013	R33008Q	33008	Missense	distal	-5	no	12.058	12.179	EPSD	ICGC;COSMIC	7.092	Up-regulation
AGC_PKG_PRKG1_ST	Q8WZ42	TTN	Q13976	PRKG1	S33013	R33011K	33011	Missense	proximal	-2	no	12.058	10.581	EPSD	ICGC;COSMIC	7.092	Down-regulation
AGC_PKG_PRKG1_ST	Q8WZ42	TTN	Q13976	PRKG1	S33013	R33012C	33012	Missense	proximal	-1	no	12.058	11.856	EPSD	ICGC;COSMIC	7.092	Down-regulation
AGC_PKG_PRKG1_ST	Q8WZ42	TTN	Q13976	PRKG1	S33013	L33014I	33014	Missense	proximal	1	no	12.058	12.086	EPSD	ICGC	7.092	Up-regulation
AGC_PKG_PRKG1_ST	Q8WZ42	TTN	Q13976	PRKG1	S33013	S33013Y	33013	Missense	central	0	yes	12.058	0.000	EPSD	ICGC	7.092	Loss
AGC_PKG_PRKG1_ST	Q8WZ42	TTN	Q13976	PRKG1	S33071	P33072Q	33072	Missense	proximal	1	no	8.448	8.721	EPSD	ICGC;COSMIC	7.092	Up-regulation
AGC_PKG_PRKG1_ST	Q8WZ42	TTN	Q13976	PRKG1	S33071	V33078M	33078	Missense	distal	7	no	8.448	8.525	EPSD	ICGC;COSMIC	7.092	Up-regulation
AGC_PKG_PRKG1_ST	Q8WZ42	TTN	Q13976	PRKG1	S33071	R33068C	33068	Missense	distal	-3	no	8.448	1.426	EPSD	ICGC;COSMIC	7.092	Loss
AGC_PKG_PRKG1_ST	Q8WZ42	TTN	Q13976	PRKG1	S33088	T33089I	33089	Missense	proximal	1	no	7.973	7.559	EPSD	ICGC;COSMIC	7.092	Down-regulation
AGC_PKG_PRKG1_ST	Q8WZ42	TTN	Q13976	PRKG1	S33088	H33091N	33091	Missense	distal	3	no	7.973	7.997	EPSD	ICGC	7.092	Up-regulation
AGC_PKG_PRKG1_ST	Q8WZ42	TTN	Q13976	PRKG1	S33088	D33084E	33084	Missense	distal	-4	no	7.973	8.118	EPSD	ICGC	7.092	Up-regulation
AGC_PKG_PRKG1_ST	Q8WZ42	TTN	Q13976	PRKG1	S33088	D33084H	33084	Missense	distal	-4	no	7.973	8.327	EPSD	ICGC;COSMIC	7.092	Up-regulation
AGC_PKG_PRKG1_ST	Q8WZ42	TTN	Q13976	PRKG1	S33088	F33085L	33085	Missense	distal	-3	no	7.973	7.505	EPSD	ICGC	7.092	Down-regulation
AGC_PKG_PRKG1_ST	Q8WZ42	TTN	Q13976	PRKG1	T33089	T33089I	33089	Missense	central	0	yes	8.762	0.000	EPSD	ICGC;COSMIC	7.092	Loss
AGC_PKG_PRKG1_ST	Q8WZ42	TTN	Q13976	PRKG1	T33089	H33091N	33091	Missense	proximal	2	no	8.762	8.752	EPSD	ICGC	7.092	Down-regulation
AGC_PKG_PRKG1_ST	Q8WZ42	TTN	Q13976	PRKG1	T33089	D33084E	33084	Missense	distal	-5	no	8.762	8.720	EPSD	ICGC	7.092	Down-regulation
AGC_PKG_PRKG1_ST	Q8WZ42	TTN	Q13976	PRKG1	T33089	D33084H	33084	Missense	distal	-5	no	8.762	8.648	EPSD	ICGC;COSMIC	7.092	Down-regulation
AGC_PKG_PRKG1_ST	Q8WZ42	TTN	Q13976	PRKG1	T33089	F33085L	33085	Missense	distal	-4	no	8.762	8.435	EPSD	ICGC	7.092	Down-regulation
AGC_PKG_PRKG1_ST	Q8WZ42	TTN	Q13976	PRKG1	S33099	E33097K	33097	Missense	proximal	-2	no	3.653	7.176	EPSD	ICGC;COSMIC	7.092	Gain
AGC_PKG_PRKG1_ST	Q8WZ42	TTN	Q13976	PRKG1	S33201	R33198Q	33198	Missense	distal	-3	no	14.703	10.868	EPSD	ICGC;COSMIC	7.092	Down-regulation
AGC_PKG_PRKG1_ST	Q8WZ42	TTN	Q13976	PRKG1	S33201	R33200H	33200	Missense	proximal	-1	no	14.703	14.555	EPSD	ICGC;COSMIC	7.092	Down-regulation
AGC_PKG_PRKG1_ST	Q8WZ42	TTN	Q13976	PRKG1	S33203	R33198Q	33198	Missense	distal	-5	no	9.978	10.099	EPSD	ICGC;COSMIC	7.092	Up-regulation
AGC_PKG_PRKG1_ST	Q8WZ42	TTN	Q13976	PRKG1	S33203	M33210I	33210	Missense	distal	7	no	9.978	9.848	EPSD	ICGC;COSMIC	7.092	Down-regulation
AGC_PKG_PRKG1_ST	Q8WZ42	TTN	Q13976	PRKG1	S33203	R33200H	33200	Missense	distal	-3	no	9.978	3.910	EPSD	ICGC;COSMIC	7.092	Loss
AGC_PKG_PRKG1_ST	Q8WZ42	TTN	Q13976	PRKG1	S33235	R33242H	33242	Missense	distal	7	no	7.154	7.071	EPSD	ICGC;COSMIC	7.092	Loss
AGC_PKG_PRKG1_ST	Q8WZ42	TTN	Q13976	PRKG1	S33235	R33233K	33233	Missense	proximal	-2	no	7.154	5.677	EPSD	ICGC	7.092	Loss
AGC_PKG_PRKG1_ST	Q8WZ42	TTN	Q13976	PRKG1	S33235	E33228K	33228	Missense	distal	-7	no	7.154	8.155	EPSD	ICGC;COSMIC	7.092	Up-regulation
AGC_PKG_PRKG1_ST	Q8WZ42	TTN	Q13976	PRKG1	S33235	P33238S	33238	Missense	distal	3	no	7.154	6.904	EPSD	ICGC;COSMIC	7.092	Loss
AGC_PKG_PRKG1_ST	Q8WZ42	TTN	Q13976	PRKG1	T33237	R33242H	33242	Missense	distal	5	no	7.701	7.651	EPSD	ICGC;COSMIC	7.092	Down-regulation
AGC_PKG_PRKG1_ST	Q8WZ42	TTN	Q13976	PRKG1	T33237	R33233K	33233	Missense	distal	-4	no	7.701	7.396	EPSD	ICGC	7.092	Down-regulation
AGC_PKG_PRKG1_ST	Q8WZ42	TTN	Q13976	PRKG1	T33237	R33244Q	33244	Missense	distal	7	no	7.701	7.659	EPSD	ICGC;COSMIC	7.092	Down-regulation
AGC_PKG_PRKG1_ST	Q8WZ42	TTN	Q13976	PRKG1	T33237	P33238S	33238	Missense	proximal	1	no	7.701	7.963	EPSD	ICGC;COSMIC	7.092	Up-regulation
AGC_PKG_PRKG1_ST	Q8WZ42	TTN	Q13976	PRKG1	T33237	P33243Q	33243	Missense	distal	6	no	7.701	7.463	EPSD	ICGC;COSMIC	7.092	Down-regulation
AGC_PKG_PRKG1_ST	Q8WZ42	TTN	Q13976	PRKG1	S33245	R33242H	33242	Missense	distal	-3	no	8.318	2.251	EPSD	ICGC;COSMIC	7.092	Loss
AGC_PKG_PRKG1_ST	Q8WZ42	TTN	Q13976	PRKG1	S33245	R33244Q	33244	Missense	proximal	-1	no	8.318	8.253	EPSD	ICGC;COSMIC	7.092	Down-regulation
AGC_PKG_PRKG1_ST	Q8WZ42	TTN	Q13976	PRKG1	S33245	P33238S	33238	Missense	distal	-7	no	8.318	9.086	EPSD	ICGC;COSMIC	7.092	Up-regulation
AGC_PKG_PRKG1_ST	Q8WZ42	TTN	Q13976	PRKG1	S33245	P33243Q	33243	Missense	proximal	-2	no	8.318	9.112	EPSD	ICGC;COSMIC	7.092	Up-regulation
AGC_PKG_PRKG1_ST	Q8WZ42	TTN	Q13976	PRKG1	S33247	S33254L	33254	Missense	distal	7	no	11.582	11.415	EPSD	ICGC;COSMIC	7.092	Down-regulation
AGC_PKG_PRKG1_ST	Q8WZ42	TTN	Q13976	PRKG1	S33247	R33242H	33242	Missense	distal	-5	no	11.582	11.784	EPSD	ICGC;COSMIC	7.092	Up-regulation
AGC_PKG_PRKG1_ST	Q8WZ42	TTN	Q13976	PRKG1	S33247	R33253K	33253	Missense	distal	6	no	11.582	11.643	EPSD	ICGC	7.092	Up-regulation
AGC_PKG_PRKG1_ST	Q8WZ42	TTN	Q13976	PRKG1	S33247	R33244Q	33244	Missense	distal	-3	no	11.582	7.747	EPSD	ICGC;COSMIC	7.092	Down-regulation
AGC_PKG_PRKG1_ST	Q8WZ42	TTN	Q13976	PRKG1	S33247	P33243Q	33243	Missense	distal	-4	no	11.582	12.080	EPSD	ICGC;COSMIC	7.092	Up-regulation
AGC_PKG_PRKG1_ST	Q8WZ42	TTN	Q13976	PRKG1	S33256	S33254L	33254	Missense	proximal	-2	no	8.196	6.310	EPSD	ICGC;COSMIC	7.092	Loss
AGC_PKG_PRKG1_ST	Q8WZ42	TTN	Q13976	PRKG1	S33256	R33263T	33263	Missense	distal	7	no	8.196	8.146	EPSD	ICGC;COSMIC	7.092	Down-regulation
AGC_PKG_PRKG1_ST	Q8WZ42	TTN	Q13976	PRKG1	S33256	R33263I	33263	Missense	distal	7	no	8.196	8.010	EPSD	ICGC	7.092	Down-regulation
AGC_PKG_PRKG1_ST	Q8WZ42	TTN	Q13976	PRKG1	S33256	R33253K	33253	Missense	distal	-3	no	8.196	5.838	EPSD	ICGC	7.092	Loss
AGC_PKG_PRKG1_ST	Q8WZ42	TTN	Q13976	PRKG1	S33256	A33262V	33262	Missense	distal	6	no	8.196	8.392	EPSD	ICGC	7.092	Up-regulation
AGC_PKG_PRKG1_ST	Q8WZ42	TTN	Q13976	PRKG1	S33443	E33440K	33440	Missense	distal	-3	no	4.260	8.843	EPSD	ICGC;COSMIC	7.092	Gain
AGC_PKG_PRKG1_ST	Q8WZ42	TTN	Q13976	PRKG1	S33451	T33448K	33448	Missense	distal	-3	no	6.490	9.297	EPSD	ICGC	7.092	Gain
AGC_PKG_PRKG1_ST	Q8WZ42	TTN	Q13976	PRKG1	S33453	E33450K	33450	Missense	distal	-3	no	2.890	7.473	EPSD	ICGC;COSMIC	7.092	Gain
AGC_PKG_PRKG1_ST	Q8WZ42	TTN	Q13976	PRKG1	S33496	R33495W	33495	Missense	proximal	-1	no	9.482	9.225	EPSD	ICGC;COSMIC	7.092	Down-regulation
AGC_PKG_PRKG1_ST	Q8WZ42	TTN	Q13976	PRKG1	S33496	E33503K	33503	Missense	distal	7	no	9.482	9.566	EPSD	ICGC;COSMIC	7.092	Up-regulation
AGC_PKG_PRKG1_ST	Q8WZ42	TTN	Q13976	PRKG1	S33496	S33496F	33496	Missense	central	0	yes	9.482	0.000	EPSD	ICGC;COSMIC	7.092	Loss
AGC_PKG_PRKG1_ST	Q8WZ42	TTN	Q13976	PRKG1	S33496	L33491I	33491	Missense	distal	-5	no	9.482	9.472	EPSD	ICGC;COSMIC	7.092	Down-regulation
AGC_PKG_PRKG1_ST	Q8WZ42	TTN	Q13976	PRKG1	S33496	R33495Q	33495	Missense	proximal	-1	no	9.482	9.417	EPSD	ICGC;COSMIC	7.092	Down-regulation
AGC_PKG_PRKG1_ST	Q8WZ42	TTN	Q13976	PRKG1	T33498	R33495W	33495	Missense	distal	-3	no	7.239	-0.434	EPSD	ICGC;COSMIC	7.092	Loss
AGC_PKG_PRKG1_ST	Q8WZ42	TTN	Q13976	PRKG1	T33498	E33503K	33503	Missense	distal	5	no	7.239	7.301	EPSD	ICGC;COSMIC	7.092	Up-regulation
AGC_PKG_PRKG1_ST	Q8WZ42	TTN	Q13976	PRKG1	T33498	A33505E	33505	Missense	distal	7	no	7.239	7.172	EPSD	ICGC	7.092	Down-regulation
AGC_PKG_PRKG1_ST	Q8WZ42	TTN	Q13976	PRKG1	T33498	S33496F	33496	Missense	proximal	-2	no	7.239	6.477	EPSD	ICGC;COSMIC	7.092	Loss
AGC_PKG_PRKG1_ST	Q8WZ42	TTN	Q13976	PRKG1	T33498	L33491I	33491	Missense	distal	-7	no	7.239	7.243	EPSD	ICGC;COSMIC	7.092	Up-regulation
AGC_PKG_PRKG1_ST	Q8WZ42	TTN	Q13976	PRKG1	T33498	R33495Q	33495	Missense	distal	-3	no	7.239	3.404	EPSD	ICGC;COSMIC	7.092	Loss
AGC_PKG_PRKG1_ST	Q8WZ42	TTN	Q13976	PRKG1	S33595	P33591Q	33591	Missense	distal	-4	no	8.417	8.914	EPSD	ICGC;COSMIC	7.092	Up-regulation
AGC_PKG_PRKG1_ST	Q8WZ42	TTN	Q13976	PRKG1	S33595	P33598T	33598	Missense	distal	3	no	8.417	8.159	EPSD	ICGC;COSMIC	7.092	Down-regulation
AGC_PKG_PRKG1_ST	Q8WZ42	TTN	Q13976	PRKG1	S33595	P33590S	33590	Missense	distal	-5	no	8.417	8.302	EPSD	ICGC	7.092	Down-regulation
AGC_PKG_PRKG1_ST	Q8WZ42	TTN	Q13976	PRKG1	S33595	P33590L	33590	Missense	distal	-5	no	8.417	8.538	EPSD	ICGC;COSMIC	7.092	Up-regulation
AGC_PKG_PRKG1_ST	Q8WZ42	TTN	Q13976	PRKG1	S33595	S33595F	33595	Missense	central	0	yes	8.417	0.000	EPSD	ICGC;COSMIC	7.092	Loss
AGC_PKG_PRKG1_ST	Q8WZ42	TTN	Q13976	PRKG1	S33595	R33592I	33592	Missense	distal	-3	no	8.417	-0.090	EPSD	ICGC;COSMIC	7.092	Loss
AGC_PKG_PRKG1_ST	Q8WZ42	TTN	Q13976	PRKG1	S33602	S33608F	33608	Missense	distal	6	no	10.132	10.324	EPSD	ICGC;COSMIC	7.092	Up-regulation
AGC_PKG_PRKG1_ST	Q8WZ42	TTN	Q13976	PRKG1	S33602	P33598T	33598	Missense	distal	-4	no	10.132	10.437	EPSD	ICGC;COSMIC	7.092	Up-regulation
AGC_PKG_PRKG1_ST	Q8WZ42	TTN	Q13976	PRKG1	S33602	S33608C	33608	Missense	distal	6	no	10.132	10.311	EPSD	ICGC;COSMIC	7.092	Up-regulation
AGC_PKG_PRKG1_ST	Q8WZ42	TTN	Q13976	PRKG1	S33602	S33608Y	33608	Missense	distal	6	no	10.132	10.326	EPSD	ICGC	7.092	Up-regulation
AGC_PKG_PRKG1_ST	Q8WZ42	TTN	Q13976	PRKG1	S33602	S33595F	33595	Missense	distal	-7	no	10.132	9.488	EPSD	ICGC;COSMIC	7.092	Down-regulation
AGC_PKG_PRKG1_ST	Q8WZ42	TTN	Q13976	PRKG1	S33614	R33611Q	33611	Missense	distal	-3	no	10.333	6.498	EPSD	ICGC;COSMIC	7.092	Loss
AGC_PKG_PRKG1_ST	Q8WZ42	TTN	Q13976	PRKG1	S33614	P33620L	33620	Missense	distal	6	no	10.333	10.461	EPSD	ICGC	7.092	Up-regulation
AGC_PKG_PRKG1_ST	Q8WZ42	TTN	Q13976	PRKG1	S33614	S33608F	33608	Missense	distal	-6	no	10.333	10.036	EPSD	ICGC;COSMIC	7.092	Down-regulation
AGC_PKG_PRKG1_ST	Q8WZ42	TTN	Q13976	PRKG1	S33614	P33617H	33617	Missense	distal	3	no	10.333	10.173	EPSD	ICGC	7.092	Down-regulation
AGC_PKG_PRKG1_ST	Q8WZ42	TTN	Q13976	PRKG1	S33614	S33608C	33608	Missense	distal	-6	no	10.333	9.961	EPSD	ICGC;COSMIC	7.092	Down-regulation
AGC_PKG_PRKG1_ST	Q8WZ42	TTN	Q13976	PRKG1	S33614	S33608Y	33608	Missense	distal	-6	no	10.333	9.969	EPSD	ICGC	7.092	Down-regulation
AGC_PKG_PRKG1_ST	Q8WZ42	TTN	Q13976	PRKG1	S33624	P33620L	33620	Missense	distal	-4	no	7.698	7.348	EPSD	ICGC	7.092	Down-regulation
AGC_PKG_PRKG1_ST	Q8WZ42	TTN	Q13976	PRKG1	S33624	T33626K	33626	Missense	proximal	2	no	7.698	7.702	EPSD	ICGC	7.092	Up-regulation
AGC_PKG_PRKG1_ST	Q8WZ42	TTN	Q13976	PRKG1	S33624	T33631K	33631	Missense	distal	7	no	7.698	7.705	EPSD	ICGC	7.092	Up-regulation
AGC_PKG_PRKG1_ST	Q8WZ42	TTN	Q13976	PRKG1	S33624	P33617H	33617	Missense	distal	-7	no	7.698	7.924	EPSD	ICGC	7.092	Up-regulation
AGC_PKG_PRKG1_ST	Q8WZ42	TTN	Q13976	PRKG1	S33624	E33627K	33627	Missense	distal	3	no	7.698	7.524	EPSD	ICGC;COSMIC	7.092	Down-regulation
AGC_PKG_PRKG1_ST	Q8WZ42	TTN	Q13976	PRKG1	S33885	Q33890H	33890	Missense	distal	5	no	8.568	8.543	EPSD	ICGC	7.092	Down-regulation
AGC_PKG_PRKG1_ST	Q8WZ42	TTN	Q13976	PRKG1	S33956	Q33957K	33957	Missense	proximal	1	no	7.465	7.500	EPSD	ICGC	7.092	Up-regulation
AGC_PKG_PRKG1_ST	Q8WZ42	TTN	Q13976	PRKG1	S33956	A33958E	33958	Missense	proximal	2	no	7.465	7.412	EPSD	ICGC	7.092	Down-regulation
AGC_PKG_PRKG1_ST	Q8WZ42	TTN	Q13976	PRKG1	S34298	H34305R	34305	Missense	distal	7	no	7.575	7.659	EPSD	ICGC;COSMIC	7.092	Up-regulation
AGC_PKG_PRKG1_ST	Q8WZ42	TTN	Q13976	PRKG1	S34298	Q34301K	34301	Missense	distal	3	no	7.575	7.585	EPSD	ICGC	7.092	Up-regulation
AGC_PKG_PRKG1_ST	Q8WZ42	TTN	Q13976	PRKG1	S34298	Q34301H	34301	Missense	distal	3	no	7.575	7.660	EPSD	ICGC;COSMIC	7.092	Up-regulation
AGC_PKG_PRKG1_ST	Q8WZ42	TTN	Q13976	PRKG1	S34298	H34297N	34297	Missense	proximal	-1	no	7.575	7.538	EPSD	ICGC;COSMIC	7.092	Down-regulation
AGC_PKG_PRKG1_ST	Q05469	LIPE	Q13976	PRKG1	S200	A194S	194	Missense	distal	-6	no	7.726	7.770	EPSD	ICGC;COSMIC	7.092	Up-regulation
AGC_PKG_PRKG1_ST	Q05469	LIPE	Q13976	PRKG1	S200	G205V	205	Missense	distal	5	no	7.726	7.715	EPSD	ICGC	7.092	Down-regulation
AGC_PKG_PRKG1_ST	Q05469	LIPE	Q13976	PRKG1	S565	A558V	558	Missense	distal	-7	no	8.424	7.721	EPSD	ICGC;COSMIC	7.092	Down-regulation
AGC_PKG_PRKG1_ST	Q05469	LIPE	Q13976	PRKG1	S565	R563M	563	Missense	proximal	-2	no	8.424	5.161	EPSD	ICGC;COSMIC	7.092	Loss
AGC_PKG_PRKG1_ST	Q05469	LIPE	Q13976	PRKG1	S607	P600H	600	Missense	distal	-7	no	6.869	7.096	EPSD	ICGC;COSMIC	7.092	Gain
AGC_PKG_PRKG1_ST	Q05469	LIPE	Q13976	PRKG1	S645	R642C	642	Missense	distal	-3	no	10.165	3.143	EPSD	ICGC;COSMIC	7.092	Loss
AGC_PKG_PRKG1_ST	Q05469	LIPE	Q13976	PRKG1	T813	R810W	810	Missense	distal	-3	no	11.780	4.107	EPSD	ICGC;COSMIC	7.092	Loss
AGC_PKG_PRKG1_ST	Q05469	LIPE	Q13976	PRKG1	T813	V809L	809	Missense	distal	-4	no	11.780	11.537	EPSD	ICGC;COSMIC	7.092	Down-regulation
AGC_PKG_PRKG1_ST	Q05469	LIPE	Q13976	PRKG1	S853	R852H	852	Missense	proximal	-1	no	9.831	9.683	PhosphoSitePlus	ICGC;COSMIC	7.092	Down-regulation
AGC_PKG_PRKG1_ST	Q05469	LIPE	Q13976	PRKG1	S855	R852H	852	Missense	distal	-3	no	9.844	3.777	EPSD	ICGC;COSMIC	7.092	Loss
AGC_PKG_PRKG1_ST	P41220	RGS2	Q13976	PRKG1	S46	S53A	53	Missense	distal	7	no	9.681	9.659	PhosphoSitePlus;EPSD	ICGC	7.092	Down-regulation
AGC_PKG_PRKG1_ST	P41220	RGS2	Q13976	PRKG1	S64	K71N	71	Missense	distal	7	no	8.464	8.408	EPSD;PhosphoSitePlus	ICGC	7.092	Down-regulation
AGC_PKG_PRKG1_ST	P41220	RGS2	Q13976	PRKG1	S179	E182D	182	Missense	distal	3	no	9.865	9.879	EPSD	ICGC;COSMIC	7.092	Up-regulation
AGC_PKG_PRKG1_ST	P41220	RGS2	Q13976	PRKG1	S179	T172I	172	Missense	distal	-7	no	9.865	8.700	EPSD	ICGC	7.092	Down-regulation
AGC_PKG_PRKG1_ST	P48995	TRPC1	Q13976	PRKG1	S206	R213C	213	Missense	distal	7	no	8.180	8.068	EPSD;PhosphoSitePlus	ICGC;COSMIC	7.092	Down-regulation
AGC_PKG_PRKG1_ST	P48995	TRPC1	Q13976	PRKG1	S279	A276T	276	Missense	distal	-3	no	8.294	7.707	EPSD	ICGC;COSMIC	7.092	Down-regulation
AGC_PKG_PRKG1_ST	P48995	TRPC1	Q13976	PRKG1	S279	R280H	280	Missense	proximal	1	no	8.294	7.958	EPSD	ICGC;COSMIC	7.092	Down-regulation
AGC_PKG_PRKG1_ST	P48995	TRPC1	Q13976	PRKG1	S279	R277Q	277	Missense	proximal	-2	no	8.294	5.329	EPSD	ICGC;COSMIC	7.092	Loss
AGC_PKG_PRKG1_ST	P48995	TRPC1	Q13976	PRKG1	T347	R344L	344	Missense	distal	-3	no	10.040	2.896	PhosphoSitePlus;EPSD	ICGC;COSMIC	7.092	Loss
AGC_PKG_PRKG1_ST	P48995	TRPC1	Q13976	PRKG1	T347	K350E	350	Missense	distal	3	no	10.040	10.214	PhosphoSitePlus;EPSD	ICGC	7.092	Up-regulation
AGC_PKG_PRKG1_ST	P48995	TRPC1	Q13976	PRKG1	T347	V354A	354	Missense	distal	7	no	10.040	10.112	PhosphoSitePlus;EPSD	ICGC;COSMIC	7.092	Up-regulation
AGC_PKG_PRKG1_ST	P48995	TRPC1	Q13976	PRKG1	T415	Y408C	408	Missense	distal	-7	no	7.467	7.461	EPSD	ICGC;COSMIC	7.092	Down-regulation
AGC_PKG_PRKG1_ST	P48995	TRPC1	Q13976	PRKG1	T415	P418S	418	Missense	distal	3	no	7.467	7.217	EPSD	ICGC;COSMIC	7.092	Down-regulation
AGC_PKG_PRKG1_ST	P48995	TRPC1	Q13976	PRKG1	T415	E410Q	410	Missense	distal	-5	no	7.467	7.313	EPSD	ICGC;COSMIC	7.092	Down-regulation
AGC_PKG_PRKG1_ST	P31645	SLC6A4	Q13976	PRKG1	S44	Q42K	42	Missense	proximal	-2	no	7.975	9.462	EPSD	ICGC;COSMIC	7.092	Up-regulation
AGC_PKG_PRKG1_ST	P31645	SLC6A4	Q13976	PRKG1	S62	T67A	67	Missense	distal	5	no	8.971	8.962	EPSD	ICGC;COSMIC	7.092	Down-regulation
AGC_PKG_PRKG1_ST	Q13976	PRKG1	Q13976	PRKG1	S27	E23K	23	Missense	distal	-4	no	10.846	11.507	EPSD	ICGC	7.092	Up-regulation
AGC_PKG_PRKG1_ST	Q15052	ARHGEF6	Q13976	PRKG1	S144	T142K	142	Missense	proximal	-2	no	4.978	7.093	EPSD	ICGC	7.092	Gain
AGC_PKG_PRKG1_ST	Q15052	ARHGEF6	Q13976	PRKG1	S150	T152N	152	Missense	proximal	2	no	9.345	9.313	EPSD	ICGC	7.092	Down-regulation
AGC_PKG_PRKG1_ST	Q15052	ARHGEF6	Q13976	PRKG1	S150	M155L	155	Missense	distal	5	no	9.345	9.234	EPSD	ICGC;COSMIC	7.092	Down-regulation
AGC_PKG_PRKG1_ST	Q76M96	CCDC80	Q13976	PRKG1	S79	V82M	82	Missense	distal	3	no	15.103	14.913	EPSD	ICGC	7.092	Down-regulation
AGC_PKG_PRKG1_ST	Q76M96	CCDC80	Q13976	PRKG1	S79	V82L	82	Missense	distal	3	no	15.103	15.245	EPSD	ICGC;COSMIC	7.092	Up-regulation
AGC_PKG_PRKG1_ST	Q76M96	CCDC80	Q13976	PRKG1	S79	R84I	84	Missense	distal	5	no	15.103	14.980	EPSD	ICGC;COSMIC	7.092	Down-regulation
AGC_PKG_PRKG1_ST	Q76M96	CCDC80	Q13976	PRKG1	S134	R131H	131	Missense	distal	-3	no	10.300	4.232	EPSD	ICGC;COSMIC	7.092	Loss
AGC_PKG_PRKG1_ST	Q76M96	CCDC80	Q13976	PRKG1	S305	K310N	310	Missense	distal	5	no	8.249	8.212	EPSD	ICGC	7.092	Down-regulation
AGC_PKG_PRKG1_ST	Q76M96	CCDC80	Q13976	PRKG1	S305	P304S	304	Missense	proximal	-1	no	8.249	8.352	EPSD	ICGC	7.092	Up-regulation
AGC_PKG_PRKG1_ST	Q76M96	CCDC80	Q13976	PRKG1	S305	S308N	308	Missense	distal	3	no	8.249	8.364	EPSD	ICGC	7.092	Up-regulation
AGC_PKG_PRKG1_ST	Q76M96	CCDC80	Q13976	PRKG1	T352	A356P	356	Missense	distal	4	no	7.459	7.589	EPSD	ICGC;COSMIC	7.092	Up-regulation
AGC_PKG_PRKG1_ST	Q76M96	CCDC80	Q13976	PRKG1	T352	P354H	354	Missense	proximal	2	no	7.459	7.503	EPSD	ICGC	7.092	Up-regulation
AGC_PKG_PRKG1_ST	Q76M96	CCDC80	Q13976	PRKG1	S366	A368E	368	Missense	proximal	2	no	10.079	10.025	EPSD	ICGC;COSMIC	7.092	Down-regulation
AGC_PKG_PRKG1_ST	Q76M96	CCDC80	Q13976	PRKG1	T370	A368E	368	Missense	proximal	-2	no	9.765	8.221	EPSD	ICGC;COSMIC	7.092	Down-regulation
AGC_PKG_PRKG1_ST	Q76M96	CCDC80	Q13976	PRKG1	T370	R374S	374	Missense	distal	4	no	9.765	9.801	EPSD	ICGC;COSMIC	7.092	Up-regulation
AGC_PKG_PRKG1_ST	Q76M96	CCDC80	Q13976	PRKG1	S409	R407I	407	Missense	proximal	-2	no	12.972	6.967	EPSD;PhosphoSitePlus	ICGC;COSMIC	7.092	Loss
AGC_PKG_PRKG1_ST	Q76M96	CCDC80	Q13976	PRKG1	S434	R432K	432	Missense	proximal	-2	no	13.432	11.954	PhosphoSitePlus;EPSD	ICGC;COSMIC	7.092	Down-regulation
AGC_PKG_PRKG1_ST	Q76M96	CCDC80	Q13976	PRKG1	S572	K575N	575	Missense	distal	3	no	7.760	7.860	EPSD	ICGC;COSMIC	7.092	Up-regulation
AGC_PKG_PRKG1_ST	Q76M96	CCDC80	Q13976	PRKG1	S572	K571T	571	Missense	proximal	-1	no	7.760	7.716	EPSD	ICGC	7.092	Down-regulation
AGC_PKG_PRKG1_ST	Q76M96	CCDC80	Q13976	PRKG1	S611	F604L	604	Missense	distal	-7	no	7.178	6.440	EPSD	ICGC	7.092	Loss
CMGC_MAPK_ERK1_MAPK1_ST	P19634	SLC9A1	P28482	MAPK1	S11	G6D	6	Missense	distal	-5	no	13.032	13.035	EPSD	ICGC;COSMIC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P19634	SLC9A1	P28482	MAPK1	S11	I7V	7	Missense	distal	-4	no	13.032	13.349	EPSD	ICGC;COSMIC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P19634	SLC9A1	P28482	MAPK1	T68	P69Q	69	Missense	proximal	1	no	13.700	5.206	EPSD	ICGC	8.102	Loss
CMGC_MAPK_ERK1_MAPK1_ST	P19634	SLC9A1	P28482	MAPK1	T68	S71I	71	Missense	distal	3	no	13.700	13.758	EPSD	ICGC;COSMIC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P19634	SLC9A1	P28482	MAPK1	S693	H689Q	689	Missense	distal	-4	no	14.394	14.443	EPSD;PhosphoSitePlus	ICGC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P19634	SLC9A1	P28482	MAPK1	S693	P687T	687	Missense	distal	-6	no	14.394	14.344	EPSD;PhosphoSitePlus	ICGC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P19634	SLC9A1	P28482	MAPK1	S693	R700S	700	Missense	distal	7	no	14.394	14.390	EPSD;PhosphoSitePlus	ICGC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P11388	TOP2A	P28482	MAPK1	S4	P8S	8	Missense	distal	4	no	13.568	13.557	EPSD	ICGC;COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P11388	TOP2A	P28482	MAPK1	S387	Q393K	393	Missense	distal	6	no	10.266	10.611	EPSD	ICGC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P11388	TOP2A	P28482	MAPK1	S802	A801D	801	Missense	proximal	-1	no	14.157	14.138	EPSD	ICGC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P11388	TOP2A	P28482	MAPK1	T950	M943T	943	Missense	distal	-7	no	14.257	14.262	EPSD	ICGC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P11388	TOP2A	P28482	MAPK1	S1115	G1122E	1122	Missense	distal	7	no	8.958	8.830	EPSD	ICGC;COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P11388	TOP2A	P28482	MAPK1	S1115	E1109K	1109	Missense	distal	-6	no	8.958	8.932	EPSD	ICGC;COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P11388	TOP2A	P28482	MAPK1	S1162	L1166F	1166	Missense	distal	4	no	16.061	15.993	EPSD	ICGC;COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P11388	TOP2A	P28482	MAPK1	S1162	P1163L	1163	Missense	proximal	1	no	16.061	7.252	EPSD	ICGC	8.102	Loss
CMGC_MAPK_ERK1_MAPK1_ST	P11388	TOP2A	P28482	MAPK1	S1164	L1166F	1166	Missense	proximal	2	no	8.463	8.451	EPSD	ICGC;COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P11388	TOP2A	P28482	MAPK1	S1164	P1163L	1163	Missense	proximal	-1	no	8.463	8.403	EPSD	ICGC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P11388	TOP2A	P28482	MAPK1	S1354	P1355S	1355	Missense	proximal	1	no	14.705	5.310	EPSD;PhosphoSitePlus	ICGC	8.102	Loss
CMGC_MAPK_ERK1_MAPK1_ST	P11388	TOP2A	P28482	MAPK1	S1354	P1350T	1350	Missense	distal	-4	no	14.705	14.392	EPSD;PhosphoSitePlus	ICGC;COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P11388	TOP2A	P28482	MAPK1	S1361	P1355S	1355	Missense	distal	-6	no	15.536	15.510	PhosphoSitePlus;EPSD	ICGC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P11388	TOP2A	P28482	MAPK1	S1393	P1395T	1395	Missense	proximal	2	no	10.974	10.924	EPSD;PhosphoSitePlus	ICGC;COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P11388	TOP2A	P28482	MAPK1	S1393	P1394T	1394	Missense	proximal	1	no	10.974	2.475	EPSD;PhosphoSitePlus	ICGC;COSMIC	8.102	Loss
CMGC_MAPK_ERK1_MAPK1_ST	P11388	TOP2A	P28482	MAPK1	S1471	S1469P	1469	Missense	proximal	-2	no	5.894	8.728	EPSD	ICGC	8.102	Gain
CMGC_MAPK_ERK1_MAPK1_ST	O00562	PITPNM1	P28482	MAPK1	T287	A282V	282	Missense	distal	-5	no	15.406	15.377	EPSD	ICGC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	O00562	PITPNM1	P28482	MAPK1	S300	S300F	300	Missense	central	0	yes	13.181	0.000	EPSD	ICGC	8.102	Loss
CMGC_MAPK_ERK1_MAPK1_ST	O00562	PITPNM1	P28482	MAPK1	S300	D302N	302	Missense	proximal	2	no	13.181	13.121	EPSD	ICGC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	O00562	PITPNM1	P28482	MAPK1	S300	G306W	306	Missense	distal	6	no	13.181	12.228	EPSD	ICGC;COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	O00562	PITPNM1	P28482	MAPK1	S326	E332Q	332	Missense	distal	6	no	13.334	13.013	EPSD	ICGC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	O00562	PITPNM1	P28482	MAPK1	S326	S329R	329	Missense	distal	3	no	13.334	13.310	EPSD	ICGC;COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	O00562	PITPNM1	P28482	MAPK1	S382	S382F	382	Missense	central	0	yes	14.761	0.000	EPSD	ICGC;COSMIC	8.102	Loss
CMGC_MAPK_ERK1_MAPK1_ST	O00562	PITPNM1	P28482	MAPK1	S382	E385D	385	Missense	distal	3	no	14.761	14.856	EPSD	ICGC;COSMIC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	O00562	PITPNM1	P28482	MAPK1	T389	S382F	382	Missense	distal	-7	no	13.607	13.586	EPSD	ICGC;COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	O00562	PITPNM1	P28482	MAPK1	T389	A396E	396	Missense	distal	7	no	13.607	13.366	EPSD	ICGC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	O00562	PITPNM1	P28482	MAPK1	T389	G393A	393	Missense	distal	4	no	13.607	13.562	EPSD	ICGC;COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	O00562	PITPNM1	P28482	MAPK1	T389	P392L	392	Missense	distal	3	no	13.607	13.696	EPSD	ICGC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	O00562	PITPNM1	P28482	MAPK1	T389	E385D	385	Missense	distal	-4	no	13.607	13.621	EPSD	ICGC;COSMIC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	O00562	PITPNM1	P28482	MAPK1	S621	L617V	617	Missense	distal	-4	no	14.648	14.599	EPSD	ICGC;COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	O00562	PITPNM1	P28482	MAPK1	S638	A637D	637	Missense	proximal	-1	no	14.568	14.549	EPSD	ICGC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	O00562	PITPNM1	P28482	MAPK1	S638	R631S	631	Missense	distal	-7	no	14.568	14.569	EPSD	ICGC;COSMIC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P15056	BRAF	P28482	MAPK1	S76	H72Y	72	Missense	distal	-4	no	8.648	8.216	EPSD	ICGC;COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P15056	BRAF	P28482	MAPK1	S151	N148S	148	Missense	distal	-3	no	15.658	15.643	EPSD	ICGC;COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P15056	BRAF	P28482	MAPK1	S151	P152S	152	Missense	proximal	1	no	15.658	6.263	EPSD	ICGC;COSMIC	8.102	Loss
CMGC_MAPK_ERK1_MAPK1_ST	P15056	BRAF	P28482	MAPK1	S151	S147R	147	Missense	distal	-4	no	15.658	15.653	EPSD	ICGC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P15056	BRAF	P28482	MAPK1	S151	P152T	152	Missense	proximal	1	no	15.658	7.160	EPSD	ICGC	8.102	Loss
CMGC_MAPK_ERK1_MAPK1_ST	P15056	BRAF	P28482	MAPK1	S316	S317P	317	Missense	proximal	1	no	5.035	14.430	EPSD	ICGC	8.102	Gain
CMGC_MAPK_ERK1_MAPK1_ST	P15056	BRAF	P28482	MAPK1	S317	S316P	316	Missense	proximal	-1	no	13.415	13.458	EPSD	ICGC;COSMIC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P15056	BRAF	P28482	MAPK1	S317	P321H	321	Missense	distal	4	no	13.415	13.239	EPSD	ICGC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P15056	BRAF	P28482	MAPK1	S317	S317P	317	Missense	central	0	yes	13.415	0.000	EPSD	ICGC	8.102	Loss
CMGC_MAPK_ERK1_MAPK1_ST	P15056	BRAF	P28482	MAPK1	S319	S316P	316	Missense	distal	-3	no	8.527	8.703	EPSD	ICGC;COSMIC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P15056	BRAF	P28482	MAPK1	S319	I326V	326	Missense	distal	7	no	8.527	8.262	EPSD	ICGC;COSMIC;GDSC;CCLE	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P15056	BRAF	P28482	MAPK1	S319	P321H	321	Missense	proximal	2	no	8.527	8.397	EPSD	ICGC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P15056	BRAF	P28482	MAPK1	S319	S317P	317	Missense	proximal	-2	no	8.527	11.361	EPSD	ICGC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P15056	BRAF	P28482	MAPK1	S323	S316P	316	Missense	distal	-7	no	9.556	9.561	EPSD	ICGC;COSMIC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P15056	BRAF	P28482	MAPK1	S323	I326V	326	Missense	distal	3	no	9.556	9.486	EPSD	ICGC;COSMIC;GDSC;CCLE	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P15056	BRAF	P28482	MAPK1	S323	P321H	321	Missense	proximal	-2	no	9.556	6.801	EPSD	ICGC	8.102	Loss
CMGC_MAPK_ERK1_MAPK1_ST	P15056	BRAF	P28482	MAPK1	S323	P328F	328	Missense	distal	5	no	9.556	9.377	EPSD	ICGC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P15056	BRAF	P28482	MAPK1	S323	S317P	317	Missense	distal	-6	no	9.556	9.583	EPSD	ICGC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P15056	BRAF	P28482	MAPK1	S333	I326V	326	Missense	distal	-7	no	15.127	15.140	EPSD	ICGC;COSMIC;GDSC;CCLE	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P15056	BRAF	P28482	MAPK1	S333	P328F	328	Missense	distal	-5	no	15.127	15.289	EPSD	ICGC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P15056	BRAF	P28482	MAPK1	S333	P334L	334	Missense	proximal	1	no	15.127	6.317	EPSD	ICGC;COSMIC	8.102	Loss
CMGC_MAPK_ERK1_MAPK1_ST	P15056	BRAF	P28482	MAPK1	S335	P328F	328	Missense	distal	-7	no	14.911	14.886	EPSD	ICGC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P15056	BRAF	P28482	MAPK1	S335	P334L	334	Missense	proximal	-1	no	14.911	14.851	EPSD	ICGC;COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P15056	BRAF	P28482	MAPK1	T401	A404D	404	Missense	distal	3	no	14.262	14.270	PhosphoSitePlus;EPSD	ICGC;COSMIC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P15056	BRAF	P28482	MAPK1	T401	S394T	394	Missense	distal	-7	no	14.262	14.249	PhosphoSitePlus;EPSD	ICGC;COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P15056	BRAF	P28482	MAPK1	S419	Q423H	423	Missense	distal	4	no	14.619	14.552	EPSD	ICGC;COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P15056	BRAF	P28482	MAPK1	S428	S429Y	429	Missense	proximal	1	no	6.641	9.027	EPSD	ICGC	8.102	Gain
CMGC_MAPK_ERK1_MAPK1_ST	P15056	BRAF	P28482	MAPK1	S675	R671Q	671	Missense	distal	-4	no	15.348	15.244	EPSD	ICGC;COSMIC;GDSC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P15056	BRAF	P28482	MAPK1	S675	D677N	677	Missense	proximal	2	no	15.348	15.287	EPSD	ICGC;COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P15056	BRAF	P28482	MAPK1	S675	R671L	671	Missense	distal	-4	no	15.348	15.133	EPSD	ICGC;COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P15056	BRAF	P28482	MAPK1	S750	S750Y	750	Missense	central	0	yes	14.197	0.000	EPSD	ICGC	8.102	Loss
CMGC_MAPK_ERK1_MAPK1_ST	P15056	BRAF	P28482	MAPK1	S750	Q756K	756	Missense	distal	6	no	14.197	14.542	EPSD	ICGC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P15056	BRAF	P28482	MAPK1	S750	P754T	754	Missense	distal	4	no	14.197	14.074	EPSD	ICGC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P15056	BRAF	P28482	MAPK1	T753	Y760H	760	Missense	distal	7	no	19.816	19.521	EPSD;PhosphoSitePlus	ICGC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P15056	BRAF	P28482	MAPK1	T753	S750Y	750	Missense	distal	-3	no	19.816	19.546	EPSD;PhosphoSitePlus	ICGC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P15056	BRAF	P28482	MAPK1	T753	Q756K	756	Missense	distal	3	no	19.816	19.746	EPSD;PhosphoSitePlus	ICGC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P15056	BRAF	P28482	MAPK1	T753	P754T	754	Missense	proximal	1	no	19.816	11.317	EPSD;PhosphoSitePlus	ICGC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P15056	BRAF	P28482	MAPK1	T753	G759E	759	Missense	distal	6	no	19.816	19.927	EPSD;PhosphoSitePlus	ICGC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P04626	ERBB2	P28482	MAPK1	T701	E695D	695	Missense	distal	-6	no	17.817	17.830	PhosphoSitePlus	ICGC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P04626	ERBB2	P28482	MAPK1	S760	A763T	763	Missense	distal	3	no	14.838	14.821	EPSD	ICGC;COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P36956	SREBF1	P28482	MAPK1	S63	S63F	63	Missense	central	0	yes	17.329	0.000	EPSD	ICGC;COSMIC	8.102	Loss
CMGC_MAPK_ERK1_MAPK1_ST	P36956	SREBF1	P28482	MAPK1	S63	G58D	58	Missense	distal	-5	no	17.329	17.331	EPSD	ICGC;COSMIC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P36956	SREBF1	P28482	MAPK1	S63	G57R	57	Missense	distal	-6	no	17.329	17.380	EPSD	ICGC;COSMIC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P36956	SREBF1	P28482	MAPK1	S63	A62D	62	Missense	proximal	-1	no	17.329	17.311	EPSD	ICGC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P36956	SREBF1	P28482	MAPK1	S63	S68P	68	Missense	distal	5	no	17.329	17.311	EPSD	ICGC;COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P36956	SREBF1	P28482	MAPK1	T105	P111T	111	Missense	distal	6	no	13.491	13.281	EPSD	ICGC;COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P36956	SREBF1	P28482	MAPK1	T105	P99H	99	Missense	distal	-6	no	13.491	13.417	EPSD	ICGC;COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P36956	SREBF1	P28482	MAPK1	T105	P111R	111	Missense	distal	6	no	13.491	13.384	EPSD	ICGC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P36956	SREBF1	P28482	MAPK1	T105	S112F	112	Missense	distal	7	no	13.491	13.839	EPSD	ICGC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P36956	SREBF1	P28482	MAPK1	S117	P111T	111	Missense	distal	-6	no	13.022	12.972	EPSD;PhosphoSitePlus	ICGC;COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P36956	SREBF1	P28482	MAPK1	S117	P111R	111	Missense	distal	-6	no	13.022	13.030	EPSD;PhosphoSitePlus	ICGC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P36956	SREBF1	P28482	MAPK1	S117	S112F	112	Missense	distal	-5	no	13.022	13.110	EPSD;PhosphoSitePlus	ICGC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P36956	SREBF1	P28482	MAPK1	S117	P114H	114	Missense	distal	-3	no	13.022	12.672	EPSD;PhosphoSitePlus	ICGC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P36956	SREBF1	P28482	MAPK1	S117	P118H	118	Missense	proximal	1	no	13.022	5.198	EPSD;PhosphoSitePlus	ICGC;COSMIC	8.102	Loss
CMGC_MAPK_ERK1_MAPK1_ST	P36956	SREBF1	P28482	MAPK1	S117	A115T	115	Missense	proximal	-2	no	13.022	13.469	EPSD;PhosphoSitePlus	ICGC;COSMIC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P36956	SREBF1	P28482	MAPK1	S117	P120L	120	Missense	distal	3	no	13.022	13.111	EPSD;PhosphoSitePlus	ICGC;COSMIC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P36956	SREBF1	P28482	MAPK1	S117	S117F	117	Missense	central	0	yes	13.022	0.000	EPSD;PhosphoSitePlus	ICGC;COSMIC	8.102	Loss
CMGC_MAPK_ERK1_MAPK1_ST	P10636	MAPT	P28482	MAPK1	T111	D116E	116	Missense	distal	5	no	12.736	12.667	EPSD	ICGC;COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P10636	MAPT	P28482	MAPK1	S228	P233H	233	Missense	distal	5	no	14.224	14.097	EPSD	ICGC;COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P10636	MAPT	P28482	MAPK1	S228	S232F	232	Missense	distal	4	no	14.224	14.046	EPSD	ICGC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P10636	MAPT	P28482	MAPK1	S228	D225N	225	Missense	distal	-3	no	14.224	14.192	EPSD	ICGC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P10636	MAPT	P28482	MAPK1	S228	V224I	224	Missense	distal	-4	no	14.224	13.907	EPSD	ICGC;COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P10636	MAPT	P28482	MAPK1	S232	P233H	233	Missense	proximal	1	no	15.028	7.204	EPSD	ICGC;COSMIC	8.102	Loss
CMGC_MAPK_ERK1_MAPK1_ST	P10636	MAPT	P28482	MAPK1	S232	S232F	232	Missense	central	0	yes	15.028	0.000	EPSD	ICGC	8.102	Loss
CMGC_MAPK_ERK1_MAPK1_ST	P10636	MAPT	P28482	MAPK1	S232	D225N	225	Missense	distal	-7	no	15.028	15.029	EPSD	ICGC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P10636	MAPT	P28482	MAPK1	S232	P239Q	239	Missense	distal	7	no	15.028	15.157	EPSD	ICGC;COSMIC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P10636	MAPT	P28482	MAPK1	S238	P233H	233	Missense	distal	-5	no	15.270	15.395	EPSD	ICGC;COSMIC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P10636	MAPT	P28482	MAPK1	S238	S232F	232	Missense	distal	-6	no	15.270	15.186	EPSD	ICGC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P10636	MAPT	P28482	MAPK1	S238	P239Q	239	Missense	proximal	1	no	15.270	6.776	EPSD	ICGC;COSMIC	8.102	Loss
CMGC_MAPK_ERK1_MAPK1_ST	P10636	MAPT	P28482	MAPK1	S428	S427F	427	Missense	proximal	-1	no	15.089	15.042	EPSD	ICGC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P10636	MAPT	P28482	MAPK1	S438	Y441H	441	Missense	distal	3	no	19.115	19.077	EPSD	ICGC;COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P10636	MAPT	P28482	MAPK1	S516	G521R	521	Missense	distal	5	no	15.969	16.020	EPSD	ICGC;COSMIC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P10636	MAPT	P28482	MAPK1	S519	G521R	521	Missense	proximal	2	no	17.679	17.774	EPSD	ICGC;COSMIC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P10636	MAPT	P28482	MAPK1	T522	G521R	521	Missense	proximal	-1	no	17.162	17.197	EPSD	ICGC;COSMIC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q13541	EIF4EBP1	P28482	MAPK1	T10	C7S	7	Missense	distal	-3	no	13.734	14.261	EPSD	ICGC;COSMIC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q13541	EIF4EBP1	P28482	MAPK1	T37	G40V	40	Missense	distal	3	no	13.590	13.564	EPSD;PhosphoSitePlus	ICGC;COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q13541	EIF4EBP1	P28482	MAPK1	T37	S35I	35	Missense	proximal	-2	no	13.590	14.530	EPSD;PhosphoSitePlus	ICGC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q13541	EIF4EBP1	P28482	MAPK1	T37	T41S	41	Missense	distal	4	no	13.590	13.703	EPSD;PhosphoSitePlus	ICGC;COSMIC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q13541	EIF4EBP1	P28482	MAPK1	T46	G40V	40	Missense	distal	-6	no	11.671	11.627	EPSD;PhosphoSitePlus	ICGC;COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q13541	EIF4EBP1	P28482	MAPK1	T46	T41S	41	Missense	distal	-5	no	11.671	11.642	EPSD;PhosphoSitePlus	ICGC;COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q13541	EIF4EBP1	P28482	MAPK1	S65	P71A	71	Missense	distal	6	no	13.530	13.233	PhosphoSitePlus;EPSD	ICGC;COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q13541	EIF4EBP1	P28482	MAPK1	S65	P71H	71	Missense	distal	6	no	13.530	13.224	PhosphoSitePlus;EPSD	ICGC;COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q13541	EIF4EBP1	P28482	MAPK1	T70	P71A	71	Missense	proximal	1	no	14.934	7.304	EPSD;PhosphoSitePlus	ICGC;COSMIC	8.102	Loss
CMGC_MAPK_ERK1_MAPK1_ST	Q13541	EIF4EBP1	P28482	MAPK1	T70	P71H	71	Missense	proximal	1	no	14.934	7.111	EPSD;PhosphoSitePlus	ICGC;COSMIC	8.102	Loss
CMGC_MAPK_ERK1_MAPK1_ST	Q13541	EIF4EBP1	P28482	MAPK1	S96	S94I	94	Missense	proximal	-2	no	8.499	9.439	EPSD	ICGC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q13541	EIF4EBP1	P28482	MAPK1	S96	H97Q	97	Missense	proximal	1	no	8.499	7.830	EPSD	ICGC;COSMIC	8.102	Loss
CMGC_MAPK_ERK1_MAPK1_ST	Q13541	EIF4EBP1	P28482	MAPK1	S96	S101C	101	Missense	distal	5	no	8.499	8.100	EPSD	ICGC;COSMIC	8.102	Loss
CMGC_MAPK_ERK1_MAPK1_ST	Q13541	EIF4EBP1	P28482	MAPK1	S101	S94I	94	Missense	distal	-7	no	15.740	15.712	EPSD	ICGC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q13541	EIF4EBP1	P28482	MAPK1	S101	R106Q	106	Missense	distal	5	no	15.740	15.569	EPSD	ICGC;COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q13541	EIF4EBP1	P28482	MAPK1	S101	G108C	108	Missense	distal	7	no	15.740	16.330	EPSD	ICGC;COSMIC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q13541	EIF4EBP1	P28482	MAPK1	S101	A107T	107	Missense	distal	6	no	15.740	15.826	EPSD	ICGC;COSMIC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q13541	EIF4EBP1	P28482	MAPK1	S101	D104Y	104	Missense	distal	3	no	15.740	15.780	EPSD	ICGC;COSMIC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q13541	EIF4EBP1	P28482	MAPK1	S101	H97Q	97	Missense	distal	-4	no	15.740	15.788	EPSD	ICGC;COSMIC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q13541	EIF4EBP1	P28482	MAPK1	S101	S101C	101	Missense	central	0	yes	15.740	0.000	EPSD	ICGC;COSMIC	8.102	Loss
CMGC_MAPK_ERK1_MAPK1_ST	Q13541	EIF4EBP1	P28482	MAPK1	S112	R106Q	106	Missense	distal	-6	no	8.221	8.198	EPSD	ICGC;COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q13541	EIF4EBP1	P28482	MAPK1	S112	G108C	108	Missense	distal	-4	no	8.221	7.844	EPSD	ICGC;COSMIC	8.102	Loss
CMGC_MAPK_ERK1_MAPK1_ST	Q13541	EIF4EBP1	P28482	MAPK1	S112	E111D	111	Missense	proximal	-1	no	8.221	8.181	EPSD	ICGC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q13541	EIF4EBP1	P28482	MAPK1	S112	A107T	107	Missense	distal	-5	no	8.221	8.199	EPSD	ICGC;COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P49715	CEBPA	P28482	MAPK1	S190	S190P	190	Missense	central	0	yes	9.122	0.000	EPSD	ICGC;COSMIC	8.102	Loss
CMGC_MAPK_ERK1_MAPK1_ST	P49715	CEBPA	P28482	MAPK1	T226	P229H	229	Missense	distal	3	no	12.549	12.638	EPSD	ICGC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P49715	CEBPA	P28482	MAPK1	T230	P229H	229	Missense	proximal	-1	no	14.607	14.565	EPSD	ICGC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P49715	CEBPA	P28482	MAPK1	S234	A240V	240	Missense	distal	6	no	16.247	16.329	EPSD	ICGC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P49715	CEBPA	P28482	MAPK1	S234	P229H	229	Missense	distal	-5	no	16.247	16.372	EPSD	ICGC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q96PH1	NOX5	P28482	MAPK1	S544	T540A	540	Missense	distal	-4	no	9.731	9.751	EPSD	ICGC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P50548	ERF	P28482	MAPK1	T3	A5E	5	Missense	proximal	2	no	12.254	12.316	EPSD	ICGC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P50548	ERF	P28482	MAPK1	T3	K2E	2	Missense	proximal	-1	no	12.254	12.226	EPSD	ICGC;COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P50548	ERF	P28482	MAPK1	S21	A15D	15	Missense	distal	-6	no	16.292	16.355	EPSD	ICGC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P50548	ERF	P28482	MAPK1	S131	P136L	136	Missense	distal	5	no	8.784	8.570	EPSD	ICGC;COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P50548	ERF	P28482	MAPK1	S431	E432K	432	Missense	proximal	1	no	8.731	-1.017	EPSD	ICGC;COSMIC	8.102	Loss
CMGC_MAPK_ERK1_MAPK1_ST	P50548	ERF	P28482	MAPK1	S431	G433V	433	Missense	proximal	2	no	8.731	8.659	EPSD	ICGC;COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P50548	ERF	P28482	MAPK1	T456	A462G	462	Missense	distal	6	no	13.659	13.878	EPSD	ICGC;COSMIC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P49790	NUP153	P28482	MAPK1	T102	P105T	105	Missense	distal	3	no	13.100	13.162	EPSD	ICGC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P49790	NUP153	P28482	MAPK1	T118	T118N	118	Missense	central	0	yes	8.475	0.000	EPSD	ICGC;COSMIC	8.102	Loss
CMGC_MAPK_ERK1_MAPK1_ST	P49790	NUP153	P28482	MAPK1	T118	P123Q	123	Missense	distal	5	no	8.475	8.355	EPSD	ICGC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P49790	NUP153	P28482	MAPK1	S164	L165P	165	Missense	proximal	1	no	2.922	11.732	EPSD	ICGC;COSMIC	8.102	Gain
CMGC_MAPK_ERK1_MAPK1_ST	P49790	NUP153	P28482	MAPK1	S240	P241H	241	Missense	proximal	1	no	13.530	5.707	EPSD	ICGC	8.102	Loss
CMGC_MAPK_ERK1_MAPK1_ST	P49790	NUP153	P28482	MAPK1	T281	P282T	282	Missense	proximal	1	no	13.490	4.991	EPSD	ICGC	8.102	Loss
CMGC_MAPK_ERK1_MAPK1_ST	P49790	NUP153	P28482	MAPK1	T281	A285E	285	Missense	distal	4	no	13.490	13.556	EPSD	ICGC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P49790	NUP153	P28482	MAPK1	S334	N337K	337	Missense	distal	3	no	12.980	12.987	EPSD;PhosphoSitePlus	ICGC;COSMIC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P49790	NUP153	P28482	MAPK1	S334	P329T	329	Missense	distal	-5	no	12.980	13.083	EPSD;PhosphoSitePlus	ICGC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P49790	NUP153	P28482	MAPK1	S334	L340F	340	Missense	distal	6	no	12.980	12.946	EPSD;PhosphoSitePlus	ICGC;COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P49790	NUP153	P28482	MAPK1	S338	N337K	337	Missense	proximal	-1	no	15.032	15.039	EPSD;PhosphoSitePlus	ICGC;COSMIC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P49790	NUP153	P28482	MAPK1	S338	L340F	340	Missense	proximal	2	no	15.032	15.020	EPSD;PhosphoSitePlus	ICGC;COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P49790	NUP153	P28482	MAPK1	T369	P362L	362	Missense	distal	-7	no	16.319	16.307	EPSD;PhosphoSitePlus	ICGC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P49790	NUP153	P28482	MAPK1	T369	Q365K	365	Missense	distal	-4	no	16.319	16.501	EPSD;PhosphoSitePlus	ICGC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P49790	NUP153	P28482	MAPK1	T369	L367I	367	Missense	proximal	-2	no	16.319	16.342	EPSD;PhosphoSitePlus	ICGC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P49790	NUP153	P28482	MAPK1	T369	P372T	372	Missense	distal	3	no	16.319	16.381	EPSD;PhosphoSitePlus	ICGC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P49790	NUP153	P28482	MAPK1	S374	L367I	367	Missense	distal	-7	no	8.568	8.548	EPSD	ICGC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P49790	NUP153	P28482	MAPK1	S374	P372T	372	Missense	proximal	-2	no	8.568	5.869	EPSD	ICGC	8.102	Loss
CMGC_MAPK_ERK1_MAPK1_ST	P49790	NUP153	P28482	MAPK1	T388	P385Q	385	Missense	distal	-3	no	12.686	12.389	EPSD;PhosphoSitePlus	ICGC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P49790	NUP153	P28482	MAPK1	T388	L387M	387	Missense	proximal	-1	no	12.686	12.695	EPSD;PhosphoSitePlus	ICGC;COSMIC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P49790	NUP153	P28482	MAPK1	T388	R394M	394	Missense	distal	6	no	12.686	12.359	EPSD;PhosphoSitePlus	ICGC;COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P49790	NUP153	P28482	MAPK1	S491	S497F	497	Missense	distal	6	no	13.237	12.796	EPSD	ICGC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P49790	NUP153	P28482	MAPK1	S491	E493V	493	Missense	proximal	2	no	13.237	13.251	EPSD	ICGC;COSMIC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P49790	NUP153	P28482	MAPK1	S498	S497F	497	Missense	proximal	-1	no	10.870	10.823	EPSD	ICGC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P49790	NUP153	P28482	MAPK1	S498	E493V	493	Missense	distal	-5	no	10.870	10.940	EPSD	ICGC;COSMIC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P49790	NUP153	P28482	MAPK1	S500	S497F	497	Missense	distal	-3	no	14.210	13.978	EPSD	ICGC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P49790	NUP153	P28482	MAPK1	S500	E493V	493	Missense	distal	-7	no	14.210	14.187	EPSD	ICGC;COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P49790	NUP153	P28482	MAPK1	S516	P523T	523	Missense	distal	7	no	12.515	12.678	PhosphoSitePlus;EPSD	ICGC;COSMIC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P49790	NUP153	P28482	MAPK1	S516	K511N	511	Missense	distal	-5	no	12.515	12.539	PhosphoSitePlus;EPSD	ICGC;COSMIC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P49790	NUP153	P28482	MAPK1	S522	P523T	523	Missense	proximal	1	no	14.700	6.201	EPSD;PhosphoSitePlus	ICGC;COSMIC	8.102	Loss
CMGC_MAPK_ERK1_MAPK1_ST	P49790	NUP153	P28482	MAPK1	S529	P523T	523	Missense	distal	-6	no	14.304	14.254	EPSD;PhosphoSitePlus	ICGC;COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P49790	NUP153	P28482	MAPK1	S529	S534Y	534	Missense	distal	5	no	14.304	14.015	EPSD;PhosphoSitePlus	ICGC;COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P49790	NUP153	P28482	MAPK1	T588	N581D	581	Missense	distal	-7	no	12.606	12.605	EPSD	ICGC;COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P49790	NUP153	P28482	MAPK1	S614	S619L	619	Missense	distal	5	no	14.401	14.169	EPSD	ICGC;COSMIC;GDSC;CCLE	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P49790	NUP153	P28482	MAPK1	S619	S619L	619	Missense	central	0	yes	13.227	0.000	EPSD	ICGC;COSMIC;GDSC;CCLE	8.102	Loss
CMGC_MAPK_ERK1_MAPK1_ST	P49790	NUP153	P28482	MAPK1	S633	P640T	640	Missense	distal	7	no	13.432	13.595	EPSD	ICGC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P49790	NUP153	P28482	MAPK1	T699	T695S	695	Missense	distal	-4	no	16.577	16.806	EPSD	ICGC;COSMIC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P49790	NUP153	P28482	MAPK1	T747	K741T	741	Missense	distal	-6	no	12.493	12.458	EPSD	ICGC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P49790	NUP153	P28482	MAPK1	T747	T747K	747	Missense	central	0	yes	12.493	0.000	EPSD	ICGC	8.102	Loss
CMGC_MAPK_ERK1_MAPK1_ST	P49790	NUP153	P28482	MAPK1	T747	P748Q	748	Missense	proximal	1	no	12.493	3.999	EPSD	ICGC	8.102	Loss
CMGC_MAPK_ERK1_MAPK1_ST	P49790	NUP153	P28482	MAPK1	S902	F903L	903	Missense	proximal	1	no	9.137	6.897	EPSD	ICGC	8.102	Loss
CMGC_MAPK_ERK1_MAPK1_ST	P49790	NUP153	P28482	MAPK1	S902	F903V	903	Missense	proximal	1	no	9.137	6.166	EPSD	ICGC;COSMIC	8.102	Loss
CMGC_MAPK_ERK1_MAPK1_ST	P49790	NUP153	P28482	MAPK1	S902	S901L	901	Missense	proximal	-1	no	9.137	9.121	EPSD	ICGC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P49790	NUP153	P28482	MAPK1	T1032	N1030S	1030	Missense	proximal	-2	no	12.934	12.920	EPSD	ICGC;COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P49790	NUP153	P28482	MAPK1	S1134	Q1140K	1140	Missense	distal	6	no	8.056	8.401	EPSD	ICGC	8.102	Gain
CMGC_MAPK_ERK1_MAPK1_ST	P49790	NUP153	P28482	MAPK1	S1134	N1137H	1137	Missense	distal	3	no	8.056	8.154	EPSD	ICGC	8.102	Gain
CMGC_MAPK_ERK1_MAPK1_ST	Q16690	DUSP5	P28482	MAPK1	T321	S320F	320	Missense	proximal	-1	no	15.882	15.836	EPSD;PhosphoSitePlus	ICGC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q16690	DUSP5	P28482	MAPK1	S346	S346N	346	Missense	central	0	yes	15.013	0.000	EPSD;PhosphoSitePlus	ICGC;COSMIC	8.102	Loss
CMGC_MAPK_ERK1_MAPK1_ST	Q16690	DUSP5	P28482	MAPK1	S376	S374I	374	Missense	proximal	-2	no	15.037	15.977	PhosphoSitePlus;EPSD	ICGC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	O95863	SNAI1	P28482	MAPK1	S11	D12Y	12	Missense	proximal	1	no	6.992	8.679	EPSD	ICGC;COSMIC	8.102	Gain
CMGC_MAPK_ERK1_MAPK1_ST	O95863	SNAI1	P28482	MAPK1	S82	R78W	78	Missense	distal	-4	no	12.900	11.957	EPSD;PhosphoSitePlus	ICGC;COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	O95863	SNAI1	P28482	MAPK1	S82	L88M	88	Missense	distal	6	no	12.900	12.873	EPSD;PhosphoSitePlus	ICGC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	O95863	SNAI1	P28482	MAPK1	S107	S112F	112	Missense	distal	5	no	18.336	18.139	EPSD	ICGC;COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	O95863	SNAI1	P28482	MAPK1	S112	V118A	118	Missense	distal	6	no	10.083	10.001	EPSD	ICGC;COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	O95863	SNAI1	P28482	MAPK1	S112	S112F	112	Missense	central	0	yes	10.083	0.000	EPSD	ICGC;COSMIC	8.102	Loss
CMGC_MAPK_ERK1_MAPK1_ST	P35568	IRS1	P28482	MAPK1	S281	H287N	287	Missense	distal	6	no	8.330	8.540	EPSD	ICGC;COSMIC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P35568	IRS1	P28482	MAPK1	S281	N278T	278	Missense	distal	-3	no	8.330	8.282	EPSD	ICGC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P35568	IRS1	P28482	MAPK1	S295	P293L	293	Missense	proximal	-2	no	9.800	7.883	EPSD	ICGC;COSMIC	8.102	Loss
CMGC_MAPK_ERK1_MAPK1_ST	P35568	IRS1	P28482	MAPK1	S295	P292L	292	Missense	distal	-3	no	9.800	9.416	EPSD	ICGC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P35568	IRS1	P28482	MAPK1	S295	T300P	300	Missense	distal	5	no	9.800	9.855	EPSD	ICGC;COSMIC;GDSC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P35568	IRS1	P28482	MAPK1	S295	V297G	297	Missense	proximal	2	no	9.800	9.872	EPSD	ICGC;COSMIC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P35568	IRS1	P28482	MAPK1	S312	G319R	319	Missense	distal	7	no	12.828	12.763	EPSD	ICGC;COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P35568	IRS1	P28482	MAPK1	S323	G319R	319	Missense	distal	-4	no	10.184	10.444	EPSD	ICGC;COSMIC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P35568	IRS1	P28482	MAPK1	S345	S345N	345	Missense	central	0	yes	14.233	0.000	EPSD	ICGC	8.102	Loss
CMGC_MAPK_ERK1_MAPK1_ST	P35568	IRS1	P28482	MAPK1	S348	H355Q	355	Missense	distal	7	no	17.404	17.300	EPSD	ICGC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P35568	IRS1	P28482	MAPK1	S348	S345N	345	Missense	distal	-3	no	17.404	17.419	EPSD	ICGC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P35568	IRS1	P28482	MAPK1	T354	H355Q	355	Missense	proximal	1	no	8.140	7.470	EPSD	ICGC	8.102	Loss
CMGC_MAPK_ERK1_MAPK1_ST	P35568	IRS1	P28482	MAPK1	S362	H355Q	355	Missense	distal	-7	no	8.870	8.889	EPSD	ICGC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P35568	IRS1	P28482	MAPK1	S362	L369H	369	Missense	distal	7	no	8.870	8.804	EPSD	ICGC;COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P35568	IRS1	P28482	MAPK1	S383	P389T	389	Missense	distal	6	no	15.450	15.240	EPSD	ICGC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P35568	IRS1	P28482	MAPK1	S388	P389T	389	Missense	proximal	1	no	13.356	4.857	EPSD	ICGC	8.102	Loss
CMGC_MAPK_ERK1_MAPK1_ST	P35568	IRS1	P28482	MAPK1	S388	S393T	393	Missense	distal	5	no	13.356	13.282	EPSD	ICGC;COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P35568	IRS1	P28482	MAPK1	S419	S412P	412	Missense	distal	-7	no	12.815	12.820	EPSD	ICGC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P35568	IRS1	P28482	MAPK1	S419	S421R	421	Missense	proximal	2	no	12.815	12.956	EPSD	ICGC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P35568	IRS1	P28482	MAPK1	S419	A414D	414	Missense	distal	-5	no	12.815	12.760	EPSD	ICGC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P35568	IRS1	P28482	MAPK1	S434	D437Y	437	Missense	distal	3	no	13.960	14.000	EPSD	ICGC;COSMIC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P35568	IRS1	P28482	MAPK1	T453	R457H	457	Missense	distal	4	no	13.742	13.600	EPSD	ICGC;COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P35568	IRS1	P28482	MAPK1	T453	A456D	456	Missense	distal	3	no	13.742	13.750	EPSD	ICGC;COSMIC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P35568	IRS1	P28482	MAPK1	T475	P479S	479	Missense	distal	4	no	8.501	8.490	EPSD	ICGC;COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P35568	IRS1	P28482	MAPK1	T495	R493C	493	Missense	proximal	-2	no	15.028	13.080	EPSD	ICGC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P35568	IRS1	P28482	MAPK1	T495	R493H	493	Missense	proximal	-2	no	15.028	14.092	EPSD	ICGC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P35568	IRS1	P28482	MAPK1	S531	S531Y	531	Missense	central	0	yes	13.822	0.000	EPSD	ICGC	8.102	Loss
CMGC_MAPK_ERK1_MAPK1_ST	P35568	IRS1	P28482	MAPK1	S636	P634S	634	Missense	proximal	-2	no	15.895	13.061	PhosphoSitePlus;EPSD	ICGC;COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P35568	IRS1	P28482	MAPK1	S636	Y632C	632	Missense	distal	-4	no	15.895	15.841	PhosphoSitePlus;EPSD	ICGC;COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P35568	IRS1	P28482	MAPK1	S639	P634S	634	Missense	distal	-5	no	8.312	8.386	EPSD;PhosphoSitePlus	ICGC;COSMIC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P35568	IRS1	P28482	MAPK1	S639	Y632C	632	Missense	distal	-7	no	8.312	8.310	EPSD;PhosphoSitePlus	ICGC;COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P35568	IRS1	P28482	MAPK1	S666	P667H	667	Missense	proximal	1	no	10.492	2.668	EPSD	ICGC;COSMIC	8.102	Loss
CMGC_MAPK_ERK1_MAPK1_ST	P35568	IRS1	P28482	MAPK1	S672	G678V	678	Missense	distal	6	no	13.704	13.566	EPSD	ICGC;COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P35568	IRS1	P28482	MAPK1	S672	D674A	674	Missense	proximal	2	no	13.704	13.590	EPSD	ICGC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P35568	IRS1	P28482	MAPK1	S672	P667H	667	Missense	distal	-5	no	13.704	13.829	EPSD	ICGC;COSMIC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P35568	IRS1	P28482	MAPK1	S745	G752S	752	Missense	distal	7	no	12.472	12.403	EPSD	ICGC;COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P35568	IRS1	P28482	MAPK1	S745	P746T	746	Missense	proximal	1	no	12.472	3.973	EPSD	ICGC	8.102	Loss
CMGC_MAPK_ERK1_MAPK1_ST	P35568	IRS1	P28482	MAPK1	S745	P746S	746	Missense	proximal	1	no	12.472	3.077	EPSD	ICGC	8.102	Loss
CMGC_MAPK_ERK1_MAPK1_ST	P35568	IRS1	P28482	MAPK1	S745	D748N	748	Missense	distal	3	no	12.472	12.376	EPSD	ICGC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P35568	IRS1	P28482	MAPK1	S792	T793A	793	Missense	proximal	1	no	7.873	8.742	EPSD	ICGC;COSMIC	8.102	Gain
CMGC_MAPK_ERK1_MAPK1_ST	P35568	IRS1	P28482	MAPK1	S918	C923F	923	Missense	distal	5	no	13.024	13.227	EPSD	ICGC;COSMIC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P35568	IRS1	P28482	MAPK1	S918	S917R	917	Missense	proximal	-1	no	13.024	13.048	EPSD	ICGC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P35568	IRS1	P28482	MAPK1	S918	P924T	924	Missense	distal	6	no	13.024	12.814	EPSD	ICGC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P35568	IRS1	P28482	MAPK1	S918	R922G	922	Missense	distal	4	no	13.024	12.998	EPSD	ICGC;COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P35568	IRS1	P28482	MAPK1	S1005	D1003N	1003	Missense	proximal	-2	no	12.461	12.943	EPSD	ICGC;COSMIC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P35568	IRS1	P28482	MAPK1	S1043	P1044T	1044	Missense	proximal	1	no	12.161	3.663	EPSD	ICGC;COSMIC	8.102	Loss
CMGC_MAPK_ERK1_MAPK1_ST	P35568	IRS1	P28482	MAPK1	S1078	A1071T	1071	Missense	distal	-7	no	12.871	12.857	EPSD	ICGC;GDSC;CCLE	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P35568	IRS1	P28482	MAPK1	T1107	S1106L	1106	Missense	proximal	-1	no	12.379	12.362	EPSD	ICGC;COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P35568	IRS1	P28482	MAPK1	T1107	R1112W	1112	Missense	distal	5	no	12.379	11.850	EPSD	ICGC;COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P35568	IRS1	P28482	MAPK1	T1107	R1112G	1112	Missense	distal	5	no	12.379	12.328	EPSD	ICGC;COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P35568	IRS1	P28482	MAPK1	S1143	D1137N	1137	Missense	distal	-6	no	8.732	8.686	EPSD	ICGC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P35568	IRS1	P28482	MAPK1	S1218	T1219P	1219	Missense	proximal	1	no	5.409	13.908	EPSD	ICGC;COSMIC;GDSC	8.102	Gain
CMGC_MAPK_ERK1_MAPK1_ST	P35568	IRS1	P28482	MAPK1	T1219	R1220H	1220	Missense	proximal	1	no	7.093	8.924	EPSD	ICGC;COSMIC	8.102	Gain
CMGC_MAPK_ERK1_MAPK1_ST	P35568	IRS1	P28482	MAPK1	S1222	R1220H	1220	Missense	proximal	-2	no	8.279	7.343	EPSD	ICGC;COSMIC	8.102	Loss
CMGC_MAPK_ERK1_MAPK1_ST	P35568	IRS1	P28482	MAPK1	S1222	T1219P	1219	Missense	distal	-3	no	8.279	8.489	EPSD	ICGC;COSMIC;GDSC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P35568	IRS1	P28482	MAPK1	S1223	R1220H	1220	Missense	distal	-3	no	8.399	8.069	EPSD	ICGC;COSMIC	8.102	Loss
CMGC_MAPK_ERK1_MAPK1_ST	P35568	IRS1	P28482	MAPK1	S1223	T1219P	1219	Missense	distal	-4	no	8.399	8.712	EPSD	ICGC;COSMIC;GDSC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P35568	IRS1	P28482	MAPK1	S1227	R1220H	1220	Missense	distal	-7	no	9.189	9.177	EPSD	ICGC;COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	O00213	APBB1	P28482	MAPK1	S175	L173P	173	Missense	proximal	-2	no	16.369	18.287	EPSD;PhosphoSitePlus	ICGC;COSMIC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	O00213	APBB1	P28482	MAPK1	S175	P176H	176	Missense	proximal	1	no	16.369	8.546	EPSD;PhosphoSitePlus	ICGC;COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P49023	PXN	P28482	MAPK1	S230	S226T	226	Missense	distal	-4	no	11.912	11.682	EPSD	ICGC;COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P49023	PXN	P28482	MAPK1	S322	S322L	322	Missense	central	0	yes	11.412	0.000	EPSD	ICGC;COSMIC	8.102	Loss
CMGC_MAPK_ERK1_MAPK1_ST	P49023	PXN	P28482	MAPK1	S322	P328L	328	Missense	distal	6	no	11.412	11.005	EPSD	ICGC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P14618	PKM	P28482	MAPK1	T15	Q14E	14	Missense	proximal	-1	no	8.640	8.666	EPSD	ICGC;COSMIC;GDSC;CCLE	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P14618	PKM	P28482	MAPK1	T15	Q14K	14	Missense	proximal	-1	no	8.640	8.694	EPSD	ICGC;COSMIC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P14618	PKM	P28482	MAPK1	S37	D34E	34	Missense	distal	-3	no	14.625	14.574	PhosphoSitePlus	ICGC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P14618	PKM	P28482	MAPK1	S37	P38T	38	Missense	proximal	1	no	14.625	6.126	PhosphoSitePlus	ICGC	8.102	Loss
CMGC_MAPK_ERK1_MAPK1_ST	P14618	PKM	P28482	MAPK1	T41	D34E	34	Missense	distal	-7	no	9.115	9.123	EPSD	ICGC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P14618	PKM	P28482	MAPK1	T41	P38T	38	Missense	distal	-3	no	9.115	8.905	EPSD	ICGC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P14618	PKM	P28482	MAPK1	S182	L183F	183	Missense	proximal	1	no	6.607	8.847	EPSD	ICGC;COSMIC	8.102	Gain
CMGC_MAPK_ERK1_MAPK1_ST	Q09472	EP300	P28482	MAPK1	S12	P8S	8	Missense	distal	-4	no	10.311	10.227	EPSD	ICGC;COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q09472	EP300	P28482	MAPK1	S12	S12P	12	Missense	central	0	yes	10.311	0.000	EPSD	ICGC;COSMIC	8.102	Loss
CMGC_MAPK_ERK1_MAPK1_ST	Q09472	EP300	P28482	MAPK1	S20	S24L	24	Missense	distal	4	no	17.537	17.427	EPSD	ICGC;COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q09472	EP300	P28482	MAPK1	S24	S24L	24	Missense	central	0	yes	9.677	0.000	EPSD	ICGC;COSMIC	8.102	Loss
CMGC_MAPK_ERK1_MAPK1_ST	Q09472	EP300	P28482	MAPK1	S26	S24L	24	Missense	proximal	-2	no	8.548	9.465	EPSD	ICGC;COSMIC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q09472	EP300	P28482	MAPK1	S28	S24L	24	Missense	distal	-4	no	8.492	8.271	EPSD	ICGC;COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q09472	EP300	P28482	MAPK1	S90	L93F	93	Missense	distal	3	no	13.019	13.061	EPSD	ICGC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q09472	EP300	P28482	MAPK1	S112	S106C	106	Missense	distal	-6	no	13.300	13.159	EPSD	ICGC;COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q09472	EP300	P28482	MAPK1	S227	Q224H	224	Missense	distal	-3	no	13.811	13.758	EPSD	ICGC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q09472	EP300	P28482	MAPK1	S227	G226V	226	Missense	proximal	-1	no	13.811	13.839	EPSD	ICGC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q09472	EP300	P28482	MAPK1	S285	P286L	286	Missense	proximal	1	no	13.630	4.820	EPSD	ICGC	8.102	Loss
CMGC_MAPK_ERK1_MAPK1_ST	Q09472	EP300	P28482	MAPK1	T317	A320S	320	Missense	distal	3	no	14.325	14.316	EPSD;PhosphoSitePlus	ICGC;COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q09472	EP300	P28482	MAPK1	S831	R838C	838	Missense	distal	7	no	12.213	12.869	EPSD	ICGC;COSMIC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q09472	EP300	P28482	MAPK1	S831	L827R	827	Missense	distal	-4	no	12.213	12.428	EPSD	ICGC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q09472	EP300	P28482	MAPK1	S833	R838C	838	Missense	distal	5	no	13.457	13.025	EPSD	ICGC;COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q09472	EP300	P28482	MAPK1	S833	L827R	827	Missense	distal	-6	no	13.457	13.557	EPSD	ICGC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q09472	EP300	P28482	MAPK1	T839	R838C	838	Missense	proximal	-1	no	14.395	14.293	EPSD	ICGC;COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q09472	EP300	P28482	MAPK1	T841	R838C	838	Missense	distal	-3	no	15.272	14.588	EPSD	ICGC;COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q09472	EP300	P28482	MAPK1	T845	R838C	838	Missense	distal	-7	no	14.243	14.211	EPSD	ICGC;COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q09472	EP300	P28482	MAPK1	T857	Q853R	853	Missense	distal	-4	no	8.061	8.164	EPSD	ICGC	8.102	Gain
CMGC_MAPK_ERK1_MAPK1_ST	Q09472	EP300	P28482	MAPK1	T885	P881S	881	Missense	distal	-4	no	15.433	15.349	EPSD	ICGC;COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q09472	EP300	P28482	MAPK1	T887	P881S	881	Missense	distal	-6	no	12.313	12.286	EPSD	ICGC;COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q09472	EP300	P28482	MAPK1	T938	P934T	934	Missense	distal	-4	no	15.126	14.813	EPSD;PhosphoSitePlus	ICGC;COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q09472	EP300	P28482	MAPK1	T938	V945L	945	Missense	distal	7	no	15.126	15.132	EPSD;PhosphoSitePlus	ICGC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q09472	EP300	P28482	MAPK1	T938	A944S	944	Missense	distal	6	no	15.126	15.423	EPSD;PhosphoSitePlus	ICGC;COSMIC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q09472	EP300	P28482	MAPK1	T938	P939S	939	Missense	proximal	1	no	15.126	5.731	EPSD;PhosphoSitePlus	ICGC	8.102	Loss
CMGC_MAPK_ERK1_MAPK1_ST	Q09472	EP300	P28482	MAPK1	T1032	S1033L	1033	Missense	proximal	1	no	7.886	8.471	EPSD	ICGC;COSMIC	8.102	Gain
CMGC_MAPK_ERK1_MAPK1_ST	Q09472	EP300	P28482	MAPK1	S1038	P1039S	1039	Missense	proximal	1	no	14.385	4.990	EPSD	ICGC;COSMIC	8.102	Loss
CMGC_MAPK_ERK1_MAPK1_ST	Q09472	EP300	P28482	MAPK1	S1038	S1033L	1033	Missense	distal	-5	no	14.385	14.460	EPSD	ICGC;COSMIC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q09472	EP300	P28482	MAPK1	S1038	Q1036K	1036	Missense	proximal	-2	no	14.385	14.959	EPSD	ICGC;COSMIC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q09472	EP300	P28482	MAPK1	S1726	D1729N	1729	Missense	distal	3	no	15.158	15.063	EPSD	ICGC;COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q09472	EP300	P28482	MAPK1	S1849	P1850S	1850	Missense	proximal	1	no	13.372	3.977	EPSD	ICGC;COSMIC	8.102	Loss
CMGC_MAPK_ERK1_MAPK1_ST	Q09472	EP300	P28482	MAPK1	T1851	P1850S	1850	Missense	proximal	-1	no	12.194	12.150	EPSD	ICGC;COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q09472	EP300	P28482	MAPK1	T1854	P1850S	1850	Missense	distal	-4	no	15.410	15.326	EPSD	ICGC;COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q09472	EP300	P28482	MAPK1	T1857	P1850S	1850	Missense	distal	-7	no	17.476	17.472	EPSD	ICGC;COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q09472	EP300	P28482	MAPK1	T1906	P1910T	1910	Missense	distal	4	no	11.793	11.670	EPSD	ICGC;COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q09472	EP300	P28482	MAPK1	T1909	P1910T	1910	Missense	proximal	1	no	15.192	6.694	EPSD	ICGC;COSMIC	8.102	Loss
CMGC_MAPK_ERK1_MAPK1_ST	Q09472	EP300	P28482	MAPK1	T1913	P1910T	1910	Missense	distal	-3	no	8.774	8.564	EPSD	ICGC;COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q09472	EP300	P28482	MAPK1	T1960	M1959I	1959	Missense	proximal	-1	no	18.000	17.984	EPSD;PhosphoSitePlus	ICGC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q09472	EP300	P28482	MAPK1	S2279	M2278I	2278	Missense	proximal	-1	no	16.736	16.720	EPSD;PhosphoSitePlus	ICGC;COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q09472	EP300	P28482	MAPK1	S2279	P2286T	2286	Missense	distal	7	no	16.736	16.899	EPSD;PhosphoSitePlus	ICGC;COSMIC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q09472	EP300	P28482	MAPK1	S2279	Q2281H	2281	Missense	proximal	2	no	16.736	16.784	EPSD;PhosphoSitePlus	ICGC;COSMIC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q09472	EP300	P28482	MAPK1	S2309	S2302Y	2302	Missense	distal	-7	no	12.769	12.738	EPSD	ICGC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q09472	EP300	P28482	MAPK1	S2366	G2362W	2362	Missense	distal	-4	no	13.450	12.768	EPSD;PhosphoSitePlus	ICGC;COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q09472	EP300	P28482	MAPK1	S2366	P2367Q	2367	Missense	proximal	1	no	13.450	4.957	EPSD;PhosphoSitePlus	ICGC;COSMIC	8.102	Loss
CMGC_MAPK_ERK1_MAPK1_ST	Q09472	EP300	P28482	MAPK1	S2366	N2370T	2370	Missense	distal	4	no	13.450	13.375	EPSD;PhosphoSitePlus	ICGC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P38936	CDKN1A	P28482	MAPK1	T57	D52N	52	Missense	distal	-5	no	13.731	13.687	EPSD;PhosphoSitePlus	ICGC;COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P38936	CDKN1A	P28482	MAPK1	T57	E56D	56	Missense	proximal	-1	no	13.731	13.691	EPSD;PhosphoSitePlus	ICGC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P38936	CDKN1A	P28482	MAPK1	T57	F51V	51	Missense	distal	-6	no	13.731	13.755	EPSD;PhosphoSitePlus	ICGC;COSMIC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P38936	CDKN1A	P28482	MAPK1	S130	P131T	131	Missense	proximal	1	no	14.369	5.870	PhosphoSitePlus;EPSD	ICGC;COSMIC	8.102	Loss
CMGC_MAPK_ERK1_MAPK1_ST	P38936	CDKN1A	P28482	MAPK1	S130	P131Q	131	Missense	proximal	1	no	14.369	5.875	PhosphoSitePlus;EPSD	ICGC;COSMIC	8.102	Loss
CMGC_MAPK_ERK1_MAPK1_ST	P38936	CDKN1A	P28482	MAPK1	S130	G129W	129	Missense	proximal	-1	no	14.369	14.302	PhosphoSitePlus;EPSD	ICGC;COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P38936	CDKN1A	P28482	MAPK1	T145	R140Q	140	Missense	distal	-5	no	8.060	8.137	EPSD	ICGC;COSMIC	8.102	Gain
CMGC_MAPK_ERK1_MAPK1_ST	P07101	TH	P28482	MAPK1	T3	P9Q	9	Missense	distal	6	no	11.473	11.185	EPSD	ICGC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P07101	TH	P28482	MAPK1	T3	Q10R	10	Missense	distal	7	no	11.473	11.357	EPSD	ICGC;COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P07101	TH	P28482	MAPK1	T8	K12R	12	Missense	distal	4	no	13.715	13.704	EPSD	ICGC;COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P07101	TH	P28482	MAPK1	T8	P9Q	9	Missense	proximal	1	no	13.715	5.221	EPSD	ICGC	8.102	Loss
CMGC_MAPK_ERK1_MAPK1_ST	P07101	TH	P28482	MAPK1	T8	Q10R	10	Missense	proximal	2	no	13.715	14.006	EPSD	ICGC;COSMIC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P15336	ATF2	P28482	MAPK1	S136	E130K	130	Missense	distal	-6	no	14.697	14.671	EPSD	ICGC;COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P15336	ATF2	P28482	MAPK1	S314	S321G	321	Missense	distal	7	no	8.196	8.265	EPSD	ICGC;COSMIC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P15336	ATF2	P28482	MAPK1	T320	S321G	321	Missense	proximal	1	no	8.431	7.761	EPSD	ICGC;COSMIC	8.102	Loss
CMGC_MAPK_ERK1_MAPK1_ST	P15336	ATF2	P28482	MAPK1	T325	S321G	321	Missense	distal	-4	no	13.109	12.843	EPSD	ICGC;COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P15336	ATF2	P28482	MAPK1	S328	S321G	321	Missense	distal	-7	no	17.310	17.296	EPSD	ICGC;COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P15336	ATF2	P28482	MAPK1	T333	S340L	340	Missense	distal	7	no	14.496	14.785	EPSD	ICGC;COSMIC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P15336	ATF2	P28482	MAPK1	T333	Q337H	337	Missense	distal	4	no	14.496	14.430	EPSD	ICGC;COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P15336	ATF2	P28482	MAPK1	T336	Q337H	337	Missense	proximal	1	no	7.782	8.452	EPSD	ICGC;COSMIC	8.102	Gain
CMGC_MAPK_ERK1_MAPK1_ST	P23443	RPS6KB1	P28482	MAPK1	S434	S441N	441	Missense	distal	7	no	14.040	14.023	EPSD;PhosphoSitePlus	ICGC;COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P23443	RPS6KB1	P28482	MAPK1	S441	P445T	445	Missense	distal	4	no	15.595	15.471	EPSD	ICGC;COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P23443	RPS6KB1	P28482	MAPK1	S441	S441N	441	Missense	central	0	yes	15.595	0.000	EPSD	ICGC;COSMIC	8.102	Loss
CMGC_MAPK_ERK1_MAPK1_ST	P23443	RPS6KB1	P28482	MAPK1	T444	P445T	445	Missense	proximal	1	no	17.708	9.209	EPSD;PhosphoSitePlus	ICGC;COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P23443	RPS6KB1	P28482	MAPK1	T444	S441N	441	Missense	distal	-3	no	17.708	17.723	EPSD;PhosphoSitePlus	ICGC;COSMIC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P23443	RPS6KB1	P28482	MAPK1	S447	P445T	445	Missense	proximal	-2	no	18.223	15.524	PhosphoSitePlus;EPSD	ICGC;COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P23443	RPS6KB1	P28482	MAPK1	S447	S441N	441	Missense	distal	-6	no	18.223	18.226	PhosphoSitePlus;EPSD	ICGC;COSMIC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P23443	RPS6KB1	P28482	MAPK1	S452	P445T	445	Missense	distal	-7	no	13.550	13.533	EPSD	ICGC;COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q92934	BAD	P28482	MAPK1	S15	P9Q	9	Missense	distal	-6	no	8.480	8.465	EPSD	ICGC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q92934	BAD	P28482	MAPK1	S15	S15Y	15	Missense	central	0	yes	8.480	0.000	EPSD	ICGC	8.102	Loss
CMGC_MAPK_ERK1_MAPK1_ST	Q92934	BAD	P28482	MAPK1	S17	S15Y	15	Missense	proximal	-2	no	8.971	9.688	EPSD	ICGC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q92934	BAD	P28482	MAPK1	S57	H61N	61	Missense	distal	4	no	8.424	8.551	EPSD	ICGC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q92934	BAD	P28482	MAPK1	S75	R72S	72	Missense	distal	-3	no	9.338	9.181	PhosphoSitePlus	ICGC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q92934	BAD	P28482	MAPK1	S75	T80K	80	Missense	distal	5	no	9.338	9.308	PhosphoSitePlus	ICGC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q92934	BAD	P28482	MAPK1	S75	S74G	74	Missense	proximal	-1	no	9.338	9.327	PhosphoSitePlus	ICGC;COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q92934	BAD	P28482	MAPK1	S91	R94W	94	Missense	distal	3	no	15.443	15.593	EPSD	ICGC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q92934	BAD	P28482	MAPK1	S146	R149L	149	Missense	distal	3	no	8.396	8.440	EPSD	ICGC;COSMIC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q92934	BAD	P28482	MAPK1	S153	R149L	149	Missense	distal	-4	no	8.934	8.719	EPSD	ICGC;COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q9GZM8	NDEL1	P28482	MAPK1	S198	S197N	197	Missense	proximal	-1	no	15.698	15.748	EPSD	ICGC;COSMIC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q9GZM8	NDEL1	P28482	MAPK1	S208	M206V	206	Missense	proximal	-2	no	6.492	8.633	EPSD	ICGC;COSMIC	8.102	Gain
CMGC_MAPK_ERK1_MAPK1_ST	Q9GZM8	NDEL1	P28482	MAPK1	T219	P220T	220	Missense	proximal	1	no	15.912	7.413	EPSD;PhosphoSitePlus	ICGC;COSMIC	8.102	Loss
CMGC_MAPK_ERK1_MAPK1_ST	Q9GZM8	NDEL1	P28482	MAPK1	S331	G330C	330	Missense	proximal	-1	no	9.062	8.994	EPSD	ICGC;COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q9GZM8	NDEL1	P28482	MAPK1	S331	G328V	328	Missense	distal	-3	no	9.062	8.943	EPSD	ICGC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q9GZM8	NDEL1	P28482	MAPK1	S331	P338L	338	Missense	distal	7	no	9.062	9.361	EPSD	ICGC;COSMIC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q9GZM8	NDEL1	P28482	MAPK1	S336	G330C	330	Missense	distal	-6	no	12.479	12.355	EPSD	ICGC;COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q9GZM8	NDEL1	P28482	MAPK1	S336	P338L	338	Missense	proximal	2	no	12.479	12.331	EPSD	ICGC;COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q9GZM8	NDEL1	P28482	MAPK1	S344	P338L	338	Missense	distal	-6	no	8.706	8.614	EPSD	ICGC;COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q07343	PDE4B	P28482	MAPK1	S145	L144P	144	Missense	proximal	-1	no	12.524	12.584	EPSD	ICGC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q9H8Y8	GORASP2	P28482	MAPK1	S26	V22L	22	Missense	distal	-4	no	15.241	15.291	EPSD	ICGC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q9H8Y8	GORASP2	P28482	MAPK1	S26	P27L	27	Missense	proximal	1	no	15.241	6.431	EPSD	ICGC;COSMIC	8.102	Loss
CMGC_MAPK_ERK1_MAPK1_ST	Q9H8Y8	GORASP2	P28482	MAPK1	S26	Q23K	23	Missense	distal	-3	no	15.241	15.280	EPSD	ICGC;COSMIC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q9H8Y8	GORASP2	P28482	MAPK1	S26	S26I	26	Missense	central	0	yes	15.241	0.000	EPSD	ICGC	8.102	Loss
CMGC_MAPK_ERK1_MAPK1_ST	Q9H8Y8	GORASP2	P28482	MAPK1	T222	M219V	219	Missense	distal	-3	no	14.584	14.714	PhosphoSitePlus;EPSD	ICGC;COSMIC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q9H8Y8	GORASP2	P28482	MAPK1	T222	G221D	221	Missense	proximal	-1	no	14.584	14.583	PhosphoSitePlus;EPSD	ICGC;COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q9H8Y8	GORASP2	P28482	MAPK1	T225	M219V	219	Missense	distal	-6	no	15.342	15.340	EPSD;PhosphoSitePlus	ICGC;COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q9H8Y8	GORASP2	P28482	MAPK1	T225	G221D	221	Missense	distal	-4	no	15.342	15.678	EPSD;PhosphoSitePlus	ICGC;COSMIC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q9H8Y8	GORASP2	P28482	MAPK1	S245	P242L	242	Missense	distal	-3	no	13.653	13.269	EPSD	ICGC;COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q9H8Y8	GORASP2	P28482	MAPK1	T249	P242L	242	Missense	distal	-7	no	8.553	8.541	EPSD	ICGC;COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q9H8Y8	GORASP2	P28482	MAPK1	T415	T415M	415	Missense	central	0	yes	13.623	0.000	EPSD	ICGC;COSMIC	8.102	Loss
CMGC_MAPK_ERK1_MAPK1_ST	Q9H8Y8	GORASP2	P28482	MAPK1	T418	T415M	415	Missense	distal	-3	no	8.875	8.647	EPSD	ICGC;COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q9H8Y8	GORASP2	P28482	MAPK1	T433	V440D	440	Missense	distal	7	no	15.171	14.884	EPSD	ICGC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q9H8Y8	GORASP2	P28482	MAPK1	T433	S432F	432	Missense	proximal	-1	no	15.171	15.125	EPSD	ICGC;COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q9H8Y8	GORASP2	P28482	MAPK1	T433	E437K	437	Missense	distal	4	no	15.171	15.186	EPSD	ICGC;COSMIC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q9H8Y8	GORASP2	P28482	MAPK1	S436	V440D	440	Missense	distal	4	no	10.147	10.149	EPSD	ICGC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q9H8Y8	GORASP2	P28482	MAPK1	S436	S432F	432	Missense	distal	-4	no	10.147	9.886	EPSD	ICGC;COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q9H8Y8	GORASP2	P28482	MAPK1	S436	E437K	437	Missense	proximal	1	no	10.147	0.399	EPSD	ICGC;COSMIC	8.102	Loss
CMGC_MAPK_ERK1_MAPK1_ST	Q9H8Y8	GORASP2	P28482	MAPK1	S441	V440D	440	Missense	proximal	-1	no	11.560	11.530	EPSD	ICGC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q9H8Y8	GORASP2	P28482	MAPK1	S441	E437K	437	Missense	distal	-4	no	11.560	11.578	EPSD	ICGC;COSMIC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P19793	RXRA	P28482	MAPK1	S21	T23M	23	Missense	proximal	2	no	16.365	16.224	EPSD	ICGC;COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P19793	RXRA	P28482	MAPK1	S49	G42V	42	Missense	distal	-7	no	14.718	14.717	EPSD	ICGC;COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P19793	RXRA	P28482	MAPK1	T82	S88I	88	Missense	distal	6	no	16.735	16.068	EPSD	ICGC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P19793	RXRA	P28482	MAPK1	S225	E221D	221	Missense	distal	-4	no	8.135	8.150	EPSD	ICGC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P19793	RXRA	P28482	MAPK1	S225	S224I	224	Missense	proximal	-1	no	8.135	8.113	EPSD	ICGC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P19793	RXRA	P28482	MAPK1	S260	P258H	258	Missense	proximal	-2	no	17.748	14.993	PhosphoSitePlus	ICGC;COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q9NVD7	PARVA	P28482	MAPK1	S4	V11I	11	Missense	distal	7	no	12.545	12.810	PhosphoSitePlus;EPSD	ICGC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q9NVD7	PARVA	P28482	MAPK1	S4	P5Q	5	Missense	proximal	1	no	12.545	4.051	PhosphoSitePlus;EPSD	ICGC	8.102	Loss
CMGC_MAPK_ERK1_MAPK1_ST	Q9NVD7	PARVA	P28482	MAPK1	S8	S14C	14	Missense	distal	6	no	14.044	13.176	EPSD;PhosphoSitePlus	ICGC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q9NVD7	PARVA	P28482	MAPK1	S8	V11I	11	Missense	distal	3	no	14.044	14.114	EPSD;PhosphoSitePlus	ICGC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q9NVD7	PARVA	P28482	MAPK1	S8	P5Q	5	Missense	distal	-3	no	14.044	13.747	EPSD;PhosphoSitePlus	ICGC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q9NVD7	PARVA	P28482	MAPK1	S14	S14C	14	Missense	central	0	yes	19.362	0.000	EPSD	ICGC	8.102	Loss
CMGC_MAPK_ERK1_MAPK1_ST	Q9NVD7	PARVA	P28482	MAPK1	S14	V11I	11	Missense	distal	-3	no	19.362	19.228	EPSD	ICGC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q9NVD7	PARVA	P28482	MAPK1	T16	S14C	14	Missense	proximal	-2	no	16.129	15.196	EPSD	ICGC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q9NVD7	PARVA	P28482	MAPK1	T16	V11I	11	Missense	distal	-5	no	16.129	16.242	EPSD	ICGC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q9NVD7	PARVA	P28482	MAPK1	S19	S14C	14	Missense	distal	-5	no	19.939	20.143	EPSD	ICGC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q9NVD7	PARVA	P28482	MAPK1	S22	D27Y	27	Missense	distal	5	no	9.420	9.107	EPSD	ICGC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q9NVD7	PARVA	P28482	MAPK1	S28	G35D	35	Missense	distal	7	no	8.562	8.490	EPSD	ICGC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q9NVD7	PARVA	P28482	MAPK1	S28	D27Y	27	Missense	proximal	-1	no	8.562	8.542	EPSD	ICGC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q9NVD7	PARVA	P28482	MAPK1	S62	A56V	56	Missense	distal	-6	no	17.691	17.644	EPSD	ICGC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	O43623	SNAI2	P28482	MAPK1	S54	W59C	59	Missense	distal	5	no	13.694	13.791	EPSD	ICGC;COSMIC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	O43623	SNAI2	P28482	MAPK1	S54	T61N	61	Missense	distal	7	no	13.694	13.524	EPSD	ICGC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	O43623	SNAI2	P28482	MAPK1	S54	S54R	54	Missense	central	0	yes	13.694	0.000	EPSD	ICGC	8.102	Loss
CMGC_MAPK_ERK1_MAPK1_ST	O43623	SNAI2	P28482	MAPK1	S87	S80F	80	Missense	distal	-7	no	18.083	18.062	PhosphoSitePlus;EPSD	ICGC;COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	O43623	SNAI2	P28482	MAPK1	S87	S81L	81	Missense	distal	-6	no	18.083	18.017	PhosphoSitePlus;EPSD	ICGC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	O43623	SNAI2	P28482	MAPK1	S104	E109K	109	Missense	distal	5	no	15.466	15.407	EPSD;PhosphoSitePlus	ICGC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	O43623	SNAI2	P28482	MAPK1	S107	Q114L	114	Missense	distal	7	no	8.000	8.170	EPSD	ICGC;COSMIC	8.102	Gain
CMGC_MAPK_ERK1_MAPK1_ST	O43623	SNAI2	P28482	MAPK1	T234	H235N	235	Missense	proximal	1	no	8.283	-3.616	EPSD	ICGC	8.102	Loss
CMGC_MAPK_ERK1_MAPK1_ST	O43623	SNAI2	P28482	MAPK1	S254	M253I	253	Missense	proximal	-1	no	9.162	9.146	EPSD	ICGC;COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	O43623	SNAI2	P28482	MAPK1	S254	E261V	261	Missense	distal	7	no	9.162	9.504	EPSD	ICGC;COSMIC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P78536	ADAM17	P28482	MAPK1	T631	F634C	634	Missense	distal	3	no	8.065	8.107	EPSD	ICGC;COSMIC	8.102	Gain
CMGC_MAPK_ERK1_MAPK1_ST	P78536	ADAM17	P28482	MAPK1	S791	A789P	789	Missense	proximal	-2	no	6.534	9.681	EPSD	ICGC;COSMIC	8.102	Gain
CMGC_MAPK_ERK1_MAPK1_ST	Q8WX93	PALLD	P28482	MAPK1	S15	S13N	13	Missense	proximal	-2	no	8.108	8.122	EPSD	ICGC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q8WX93	PALLD	P28482	MAPK1	S15	M17I	17	Missense	proximal	2	no	8.108	8.128	EPSD	ICGC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q8WX93	PALLD	P28482	MAPK1	S15	S9N	9	Missense	distal	-6	no	8.108	8.111	EPSD	ICGC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q8WX93	PALLD	P28482	MAPK1	S71	H78N	78	Missense	distal	7	no	13.470	13.230	EPSD	ICGC;COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q8WX93	PALLD	P28482	MAPK1	S125	A123S	123	Missense	proximal	-2	no	12.744	13.057	EPSD	ICGC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q8WX93	PALLD	P28482	MAPK1	T147	K153N	153	Missense	distal	6	no	10.837	10.684	EPSD	ICGC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q8WX93	PALLD	P28482	MAPK1	S166	G162E	162	Missense	distal	-4	no	8.078	8.399	EPSD	ICGC	8.102	Gain
CMGC_MAPK_ERK1_MAPK1_ST	Q8WX93	PALLD	P28482	MAPK1	T635	K631Q	631	Missense	distal	-4	no	13.039	12.858	EPSD	ICGC;COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q8WX93	PALLD	P28482	MAPK1	S641	P648H	648	Missense	distal	7	no	15.205	15.439	EPSD	ICGC;COSMIC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q8WX93	PALLD	P28482	MAPK1	S979	E983D	983	Missense	distal	4	no	13.531	13.461	EPSD	ICGC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q15797	SMAD1	P28482	MAPK1	S11	S8F	8	Missense	distal	-3	no	15.056	14.824	EPSD	ICGC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q15797	SMAD1	P28482	MAPK1	S11	S5R	5	Missense	distal	-6	no	15.056	15.091	EPSD	ICGC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q15797	SMAD1	P28482	MAPK1	S11	L18I	18	Missense	distal	7	no	15.056	15.316	EPSD	ICGC;COSMIC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q15797	SMAD1	P28482	MAPK1	S187	N180H	180	Missense	distal	-7	no	16.983	16.969	EPSD;PhosphoSitePlus	ICGC;COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q15797	SMAD1	P28482	MAPK1	S187	P188T	188	Missense	proximal	1	no	16.983	8.484	EPSD;PhosphoSitePlus	ICGC;COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q15797	SMAD1	P28482	MAPK1	S187	P183S	183	Missense	distal	-4	no	16.983	16.899	EPSD;PhosphoSitePlus	ICGC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q15797	SMAD1	P28482	MAPK1	S195	T202A	202	Missense	distal	7	no	16.646	16.675	PhosphoSitePlus;EPSD	ICGC;COSMIC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q15797	SMAD1	P28482	MAPK1	S195	G197W	197	Missense	proximal	2	no	16.646	16.373	PhosphoSitePlus;EPSD	ICGC;COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q15797	SMAD1	P28482	MAPK1	S195	P188T	188	Missense	distal	-7	no	16.646	16.629	PhosphoSitePlus;EPSD	ICGC;COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q15797	SMAD1	P28482	MAPK1	S206	T202A	202	Missense	distal	-4	no	16.952	16.972	EPSD;PhosphoSitePlus	ICGC;COSMIC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q15797	SMAD1	P28482	MAPK1	T452	W446L	446	Missense	distal	-6	no	8.199	8.319	EPSD	ICGC;COSMIC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q15797	SMAD1	P28482	MAPK1	T452	W446C	446	Missense	distal	-6	no	8.199	8.244	EPSD	ICGC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q15797	SMAD1	P28482	MAPK1	T452	P457L	457	Missense	distal	5	no	8.199	7.985	EPSD	ICGC;COSMIC	8.102	Loss
CMGC_MAPK_ERK1_MAPK1_ST	Q15797	SMAD1	P28482	MAPK1	S456	P457L	457	Missense	proximal	1	no	12.915	4.106	EPSD	ICGC;COSMIC	8.102	Loss
CMGC_MAPK_ERK1_MAPK1_ST	Q15797	SMAD1	P28482	MAPK1	S462	P457L	457	Missense	distal	-5	no	9.883	10.032	EPSD	ICGC;COSMIC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q15797	SMAD1	P28482	MAPK1	S463	P457L	457	Missense	distal	-6	no	9.283	9.191	EPSD	ICGC;COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q13127	REST	P28482	MAPK1	S734	P735S	735	Missense	proximal	1	no	13.489	4.094	EPSD	ICGC;COSMIC	8.102	Loss
CMGC_MAPK_ERK1_MAPK1_ST	Q13127	REST	P28482	MAPK1	S750	I747M	747	Missense	distal	-3	no	13.959	13.962	EPSD	ICGC;COSMIC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q13127	REST	P28482	MAPK1	S750	M753I	753	Missense	distal	3	no	13.959	14.001	EPSD	ICGC;COSMIC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q13127	REST	P28482	MAPK1	S750	Q746K	746	Missense	distal	-4	no	13.959	14.140	EPSD	ICGC;COSMIC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q13127	REST	P28482	MAPK1	S766	K762Q	762	Missense	distal	-4	no	13.930	13.748	EPSD	ICGC;COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q13127	REST	P28482	MAPK1	S782	Q789H	789	Missense	distal	7	no	14.177	14.281	EPSD	ICGC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q13127	REST	P28482	MAPK1	S782	V777F	777	Missense	distal	-5	no	14.177	14.244	EPSD	ICGC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q13127	REST	P28482	MAPK1	S861	D859V	859	Missense	proximal	-2	no	10.701	12.130	PhosphoSitePlus;EPSD	ICGC;COSMIC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q13127	REST	P28482	MAPK1	S861	E858A	858	Missense	distal	-3	no	10.701	10.514	PhosphoSitePlus;EPSD	ICGC;COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q13127	REST	P28482	MAPK1	S864	D859V	859	Missense	distal	-5	no	16.895	16.922	EPSD;PhosphoSitePlus	ICGC;COSMIC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q13127	REST	P28482	MAPK1	S864	E858A	858	Missense	distal	-6	no	16.895	16.845	EPSD;PhosphoSitePlus	ICGC;COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q13127	REST	P28482	MAPK1	S971	P975L	975	Missense	distal	4	no	16.928	16.807	EPSD	ICGC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q13127	REST	P28482	MAPK1	S971	S977L	977	Missense	distal	6	no	16.928	16.521	EPSD	ICGC;COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q04637	EIF4G1	P28482	MAPK1	S15	P19L	19	Missense	distal	4	no	16.266	16.145	EPSD	ICGC;COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q04637	EIF4G1	P28482	MAPK1	S15	P14S	14	Missense	proximal	-1	no	16.266	16.222	EPSD	ICGC;COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q04637	EIF4G1	P28482	MAPK1	T43	A38S	38	Missense	distal	-5	no	12.314	12.264	EPSD	ICGC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q04637	EIF4G1	P28482	MAPK1	T43	S45F	45	Missense	proximal	2	no	12.314	12.183	EPSD	ICGC;COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q04637	EIF4G1	P28482	MAPK1	T205	P208S	208	Missense	distal	3	no	12.516	12.586	EPSD	ICGC;COSMIC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q04637	EIF4G1	P28482	MAPK1	T205	P208H	208	Missense	distal	3	no	12.516	12.605	EPSD	ICGC;GDSC;CCLE	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q04637	EIF4G1	P28482	MAPK1	T207	P208S	208	Missense	proximal	1	no	15.634	6.239	EPSD	ICGC;COSMIC	8.102	Loss
CMGC_MAPK_ERK1_MAPK1_ST	Q04637	EIF4G1	P28482	MAPK1	T207	P208H	208	Missense	proximal	1	no	15.634	7.810	EPSD	ICGC;GDSC;CCLE	8.102	Loss
CMGC_MAPK_ERK1_MAPK1_ST	Q04637	EIF4G1	P28482	MAPK1	T223	P224S	224	Missense	proximal	1	no	11.233	1.838	EPSD	ICGC;COSMIC	8.102	Loss
CMGC_MAPK_ERK1_MAPK1_ST	Q04637	EIF4G1	P28482	MAPK1	S314	P310L	310	Missense	distal	-4	no	13.497	13.192	EPSD	ICGC;COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q04637	EIF4G1	P28482	MAPK1	S314	P310H	310	Missense	distal	-4	no	13.497	13.255	EPSD	ICGC;COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q04637	EIF4G1	P28482	MAPK1	S416	E420K	420	Missense	distal	4	no	13.619	13.633	EPSD	ICGC;COSMIC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q04637	EIF4G1	P28482	MAPK1	S450	T449I	449	Missense	proximal	-1	no	13.151	13.127	EPSD	ICGC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q04637	EIF4G1	P28482	MAPK1	S1092	A1086S	1086	Missense	distal	-6	no	8.122	8.135	EPSD	ICGC;COSMIC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q04637	EIF4G1	P28482	MAPK1	T1179	R1184Q	1184	Missense	distal	5	no	14.265	14.095	EPSD	ICGC;COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q04637	EIF4G1	P28482	MAPK1	S1185	R1184Q	1184	Missense	proximal	-1	no	8.221	8.199	EPSD	ICGC;COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q02224	CENPE	P28482	MAPK1	S130	R128H	128	Missense	proximal	-2	no	8.500	7.563	EPSD	ICGC;COSMIC	8.102	Loss
CMGC_MAPK_ERK1_MAPK1_ST	Q02224	CENPE	P28482	MAPK1	S312	L317F	317	Missense	distal	5	no	9.305	9.339	EPSD	ICGC;COSMIC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q02224	CENPE	P28482	MAPK1	S312	T316K	316	Missense	distal	4	no	9.305	9.405	EPSD	ICGC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q02224	CENPE	P28482	MAPK1	S312	C306F	306	Missense	distal	-6	no	9.305	9.361	EPSD	ICGC;COSMIC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q02224	CENPE	P28482	MAPK1	S2605	E2603K	2603	Missense	proximal	-2	no	14.093	14.053	EPSD;PhosphoSitePlus	ICGC;COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q02224	CENPE	P28482	MAPK1	S2608	E2603K	2603	Missense	distal	-5	no	15.650	15.628	EPSD;PhosphoSitePlus	ICGC;COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q02224	CENPE	P28482	MAPK1	T2622	R2629Q	2629	Missense	distal	7	no	13.092	13.207	EPSD	ICGC;COSMIC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q02224	CENPE	P28482	MAPK1	T2622	K2617E	2617	Missense	distal	-5	no	13.092	13.114	EPSD	ICGC;COSMIC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q02224	CENPE	P28482	MAPK1	T2622	Q2625R	2625	Missense	distal	3	no	13.092	13.070	EPSD	ICGC;COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q02224	CENPE	P28482	MAPK1	T2622	R2629W	2629	Missense	distal	7	no	13.092	14.064	EPSD	ICGC;COSMIC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q02224	CENPE	P28482	MAPK1	S2639	F2645S	2645	Missense	distal	6	no	15.002	15.443	PhosphoSitePlus;EPSD	ICGC;COSMIC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q02224	CENPE	P28482	MAPK1	S2654	P2655T	2655	Missense	proximal	1	no	13.737	5.239	EPSD;PhosphoSitePlus	ICGC	8.102	Loss
CMGC_MAPK_ERK1_MAPK1_ST	Q02224	CENPE	P28482	MAPK1	S2654	R2648G	2648	Missense	distal	-6	no	13.737	13.686	EPSD;PhosphoSitePlus	ICGC;COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P50616	TOB1	P28482	MAPK1	S143	Q137H	137	Missense	distal	-6	no	9.563	9.504	EPSD	ICGC;COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P50616	TOB1	P28482	MAPK1	S143	A136T	136	Missense	distal	-7	no	9.563	9.548	EPSD	ICGC;COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P50616	TOB1	P28482	MAPK1	S152	P153S	153	Missense	proximal	1	no	13.582	4.187	EPSD;PhosphoSitePlus	ICGC;COSMIC	8.102	Loss
CMGC_MAPK_ERK1_MAPK1_ST	P50616	TOB1	P28482	MAPK1	S152	H159N	159	Missense	distal	7	no	13.582	13.342	EPSD;PhosphoSitePlus	ICGC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P50616	TOB1	P28482	MAPK1	S154	P153S	153	Missense	proximal	-1	no	15.193	15.149	PhosphoSitePlus;EPSD	ICGC;COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P50616	TOB1	P28482	MAPK1	S154	H159N	159	Missense	distal	5	no	15.193	15.265	PhosphoSitePlus;EPSD	ICGC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P50616	TOB1	P28482	MAPK1	S164	H159N	159	Missense	distal	-5	no	14.103	14.004	EPSD;PhosphoSitePlus	ICGC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P50616	TOB1	P28482	MAPK1	S205	V201G	201	Missense	distal	-4	no	14.727	14.731	EPSD	ICGC;COSMIC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P50616	TOB1	P28482	MAPK1	S205	R203S	203	Missense	proximal	-2	no	14.727	13.711	EPSD	ICGC;COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P50616	TOB1	P28482	MAPK1	S268	K263N	263	Missense	distal	-5	no	14.102	14.125	EPSD	ICGC;COSMIC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P49815	TSC2	P28482	MAPK1	S540	R537L	537	Missense	distal	-3	no	13.757	13.393	EPSD	ICGC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P49815	TSC2	P28482	MAPK1	S664	G671A	671	Missense	distal	7	no	17.995	18.107	PhosphoSitePlus	ICGC;COSMIC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P49815	TSC2	P28482	MAPK1	S923	E929K	929	Missense	distal	6	no	8.522	8.545	EPSD	ICGC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P49815	TSC2	P28482	MAPK1	T927	R934M	934	Missense	distal	7	no	13.942	14.298	EPSD	ICGC;COSMIC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P49815	TSC2	P28482	MAPK1	S932	E929K	929	Missense	distal	-3	no	9.149	9.071	EPSD	ICGC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P49815	TSC2	P28482	MAPK1	S932	R934M	934	Missense	proximal	2	no	9.149	8.845	EPSD	ICGC;COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P49815	TSC2	P28482	MAPK1	S946	A950S	950	Missense	distal	4	no	8.996	9.090	EPSD	ICGC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P49815	TSC2	P28482	MAPK1	S960	L957F	957	Missense	distal	-3	no	11.546	11.521	EPSD	ICGC;COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P49815	TSC2	P28482	MAPK1	S1002	S1002F	1002	Missense	central	0	yes	8.547	0.000	EPSD	ICGC;COSMIC	8.102	Loss
CMGC_MAPK_ERK1_MAPK1_ST	P49815	TSC2	P28482	MAPK1	S1002	S1002Y	1002	Missense	central	0	yes	8.547	0.000	EPSD	ICGC;COSMIC	8.102	Loss
CMGC_MAPK_ERK1_MAPK1_ST	P49815	TSC2	P28482	MAPK1	S1045	G1048S	1048	Missense	distal	3	no	14.811	14.797	EPSD	ICGC;COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P49815	TSC2	P28482	MAPK1	S1388	S1388L	1388	Missense	central	0	yes	13.389	0.000	EPSD	ICGC;COSMIC	8.102	Loss
CMGC_MAPK_ERK1_MAPK1_ST	P10415	BCL2	P28482	MAPK1	T56	A60V	60	Missense	distal	4	no	14.539	14.533	EPSD;PhosphoSitePlus	ICGC;COSMIC;GDSC;CCLE	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P10415	BCL2	P28482	MAPK1	T56	H58Q	58	Missense	proximal	2	no	14.539	14.490	EPSD;PhosphoSitePlus	ICGC;COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P10415	BCL2	P28482	MAPK1	T56	H58P	58	Missense	proximal	2	no	14.539	14.668	EPSD;PhosphoSitePlus	ICGC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P10415	BCL2	P28482	MAPK1	T56	P59A	59	Missense	distal	3	no	14.539	14.617	EPSD;PhosphoSitePlus	ICGC;COSMIC;GDSC;CCLE	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P10415	BCL2	P28482	MAPK1	T56	S62F	62	Missense	distal	6	no	14.539	14.098	EPSD;PhosphoSitePlus	ICGC;COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P10415	BCL2	P28482	MAPK1	T56	P59S	59	Missense	distal	3	no	14.539	14.608	EPSD;PhosphoSitePlus	ICGC;COSMIC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P10415	BCL2	P28482	MAPK1	T56	P53S	53	Missense	distal	-3	no	14.539	14.362	EPSD;PhosphoSitePlus	ICGC;COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P10415	BCL2	P28482	MAPK1	T56	P59L	59	Missense	distal	3	no	14.539	14.628	EPSD;PhosphoSitePlus	ICGC;COSMIC;GDSC;CCLE	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P10415	BCL2	P28482	MAPK1	T56	Q52R	52	Missense	distal	-4	no	14.539	14.642	EPSD;PhosphoSitePlus	ICGC;COSMIC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P10415	BCL2	P28482	MAPK1	T56	F49L	49	Missense	distal	-7	no	14.539	14.551	EPSD;PhosphoSitePlus	ICGC;COSMIC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P10415	BCL2	P28482	MAPK1	T56	A60T	60	Missense	distal	4	no	14.539	14.519	EPSD;PhosphoSitePlus	ICGC;COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P10415	BCL2	P28482	MAPK1	T56	T56M	56	Missense	central	0	yes	14.539	0.000	EPSD;PhosphoSitePlus	ICGC	8.102	Loss
CMGC_MAPK_ERK1_MAPK1_ST	P10415	BCL2	P28482	MAPK1	T74	A81V	81	Missense	distal	7	no	15.881	15.983	PhosphoSitePlus;EPSD	ICGC;COSMIC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P10415	BCL2	P28482	MAPK1	S87	P88Q	88	Missense	proximal	1	no	14.286	5.792	EPSD;PhosphoSitePlus	ICGC;COSMIC	8.102	Loss
CMGC_MAPK_ERK1_MAPK1_ST	P10415	BCL2	P28482	MAPK1	S87	L86V	86	Missense	proximal	-1	no	14.286	14.320	EPSD;PhosphoSitePlus	ICGC;COSMIC;GDSC;CCLE	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P10415	BCL2	P28482	MAPK1	S87	S87R	87	Missense	central	0	yes	14.286	0.000	EPSD;PhosphoSitePlus	ICGC;COSMIC	8.102	Loss
CMGC_MAPK_ERK1_MAPK1_ST	P10415	BCL2	P28482	MAPK1	S87	A81V	81	Missense	distal	-6	no	14.286	14.238	EPSD;PhosphoSitePlus	ICGC;COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q9NQ66	PLCB1	P28482	MAPK1	T39	I41V	41	Missense	proximal	2	no	15.441	15.558	EPSD	ICGC;COSMIC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q9NQ66	PLCB1	P28482	MAPK1	T39	T45N	45	Missense	distal	6	no	15.441	15.555	EPSD	ICGC;COSMIC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q9NQ66	PLCB1	P28482	MAPK1	T39	D46H	46	Missense	distal	7	no	15.441	15.667	EPSD	ICGC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q9NQ66	PLCB1	P28482	MAPK1	T39	D32E	32	Missense	distal	-7	no	15.441	15.449	EPSD	ICGC;COSMIC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q9NQ66	PLCB1	P28482	MAPK1	S387	M382L	382	Missense	distal	-5	no	8.431	8.428	EPSD	ICGC;COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q9NQ66	PLCB1	P28482	MAPK1	S410	H414Y	414	Missense	distal	4	no	9.459	9.429	EPSD	ICGC;COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q9NQ66	PLCB1	P28482	MAPK1	S410	E412D	412	Missense	proximal	2	no	9.459	9.510	EPSD	ICGC;COSMIC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q9NQ66	PLCB1	P28482	MAPK1	S410	L409I	409	Missense	proximal	-1	no	9.459	9.453	EPSD	ICGC;COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q9NQ66	PLCB1	P28482	MAPK1	S417	Q420R	420	Missense	distal	3	no	16.300	16.278	EPSD	ICGC;COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q9NQ66	PLCB1	P28482	MAPK1	S417	H414Y	414	Missense	distal	-3	no	16.300	16.203	EPSD	ICGC;COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q9NQ66	PLCB1	P28482	MAPK1	S417	E412D	412	Missense	distal	-5	no	16.300	16.345	EPSD	ICGC;COSMIC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q9NQ66	PLCB1	P28482	MAPK1	S454	M456V	456	Missense	proximal	2	no	11.664	11.801	EPSD	ICGC;COSMIC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q9NQ66	PLCB1	P28482	MAPK1	S454	P451S	451	Missense	distal	-3	no	11.664	11.487	EPSD	ICGC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q9NQ66	PLCB1	P28482	MAPK1	S454	S448Y	448	Missense	distal	-6	no	11.664	11.550	EPSD	ICGC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q9NQ66	PLCB1	P28482	MAPK1	S501	P502Q	502	Missense	proximal	1	no	17.571	9.077	EPSD	ICGC;COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q9NQ66	PLCB1	P28482	MAPK1	S582	P583Q	583	Missense	proximal	1	no	13.843	5.349	EPSD	ICGC;COSMIC	8.102	Loss
CMGC_MAPK_ERK1_MAPK1_ST	Q9NQ66	PLCB1	P28482	MAPK1	T871	K873R	873	Missense	proximal	2	no	13.510	13.691	EPSD	ICGC;COSMIC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q9NQ66	PLCB1	P28482	MAPK1	T871	A878V	878	Missense	distal	7	no	13.510	13.612	EPSD	ICGC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q9NQ66	PLCB1	P28482	MAPK1	S982	D984Y	984	Missense	proximal	2	no	16.923	16.743	PhosphoSitePlus	ICGC;COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q9NQ66	PLCB1	P28482	MAPK1	S982	K976R	976	Missense	distal	-6	no	16.923	16.946	PhosphoSitePlus	ICGC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q9NQ66	PLCB1	P28482	MAPK1	T1197	E1201K	1201	Missense	distal	4	no	16.585	16.599	EPSD	ICGC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q9NQ66	PLCB1	P28482	MAPK1	T1197	K1196N	1196	Missense	proximal	-1	no	16.585	16.578	EPSD	ICGC;COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q9NQ66	PLCB1	P28482	MAPK1	T1197	G1191E	1191	Missense	distal	-6	no	16.585	16.639	EPSD	ICGC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q9NQ66	PLCB1	P28482	MAPK1	S1199	E1201K	1201	Missense	proximal	2	no	8.231	8.230	EPSD	ICGC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q9NQ66	PLCB1	P28482	MAPK1	S1199	K1196N	1196	Missense	distal	-3	no	8.231	8.327	EPSD	ICGC;COSMIC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q9NQ66	PLCB1	P28482	MAPK1	S1199	G1205R	1205	Missense	distal	6	no	8.231	8.201	EPSD	ICGC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q9NQ66	PLCB1	P28482	MAPK1	S1200	E1201K	1201	Missense	proximal	1	no	10.684	0.936	EPSD	ICGC	8.102	Loss
CMGC_MAPK_ERK1_MAPK1_ST	Q9NQ66	PLCB1	P28482	MAPK1	S1200	K1196N	1196	Missense	distal	-4	no	10.684	10.652	EPSD	ICGC;COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q9NQ66	PLCB1	P28482	MAPK1	S1200	G1205R	1205	Missense	distal	5	no	10.684	10.735	EPSD	ICGC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P17655	CAPN2	P28482	MAPK1	S50	P49Q	49	Missense	proximal	-1	no	8.446	8.405	PhosphoSitePlus	ICGC;COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P17655	CAPN2	P28482	MAPK1	S67	S68G	68	Missense	proximal	1	no	8.354	7.683	EPSD	ICGC;COSMIC	8.102	Loss
CMGC_MAPK_ERK1_MAPK1_ST	P17655	CAPN2	P28482	MAPK1	S67	L63S	63	Missense	distal	-4	no	8.354	8.574	EPSD	ICGC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P17655	CAPN2	P28482	MAPK1	S277	L281V	281	Missense	distal	4	no	8.508	8.519	EPSD	ICGC;COSMIC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P17655	CAPN2	P28482	MAPK1	S277	G276R	276	Missense	proximal	-1	no	8.508	8.543	EPSD	ICGC;COSMIC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P17655	CAPN2	P28482	MAPK1	S277	R283H	283	Missense	distal	6	no	8.508	8.310	EPSD	ICGC;COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P17655	CAPN2	P28482	MAPK1	T344	R337H	337	Missense	distal	-7	no	12.479	12.468	EPSD	ICGC;COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P17655	CAPN2	P28482	MAPK1	T344	R337L	337	Missense	distal	-7	no	12.479	12.472	EPSD	ICGC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P17655	CAPN2	P28482	MAPK1	T344	S350I	350	Missense	distal	6	no	12.479	11.812	EPSD	ICGC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P17655	CAPN2	P28482	MAPK1	T344	D351N	351	Missense	distal	7	no	12.479	12.466	EPSD	ICGC;COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P17655	CAPN2	P28482	MAPK1	T344	E339D	339	Missense	distal	-5	no	12.479	12.524	EPSD	ICGC;COSMIC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P17655	CAPN2	P28482	MAPK1	T380	C374Y	374	Missense	distal	-6	no	11.058	11.085	EPSD	ICGC;COSMIC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P17655	CAPN2	P28482	MAPK1	T380	P385S	385	Missense	distal	5	no	11.058	11.076	EPSD	ICGC;COSMIC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P17655	CAPN2	P28482	MAPK1	T464	A458T	458	Missense	distal	-6	no	8.285	8.274	EPSD	ICGC;COSMIC;GDSC;CCLE	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P30041	PRDX6	P28482	MAPK1	T177	R174S	174	Missense	distal	-3	no	13.903	13.747	PhosphoSitePlus	ICGC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P30041	PRDX6	P28482	MAPK1	T177	A171S	171	Missense	distal	-6	no	13.903	13.917	PhosphoSitePlus	ICGC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P30041	PRDX6	P28482	MAPK1	T177	D183Y	183	Missense	distal	6	no	13.903	13.330	PhosphoSitePlus	ICGC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q9BY84	DUSP16	P28482	MAPK1	S446	L442I	442	Missense	distal	-4	no	13.637	13.271	PhosphoSitePlus	ICGC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	O75030	MITF	P28482	MAPK1	S414	R420W	420	Missense	distal	6	no	15.800	14.876	EPSD	ICGC;COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	O75030	MITF	P28482	MAPK1	S414	D416N	416	Missense	proximal	2	no	15.800	15.739	EPSD	ICGC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	O75030	MITF	P28482	MAPK1	S491	G494D	494	Missense	distal	3	no	13.748	13.751	EPSD	ICGC;COSMIC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	O75030	MITF	P28482	MAPK1	S491	D488N	488	Missense	distal	-3	no	13.748	13.716	EPSD	ICGC;COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	O75030	MITF	P28482	MAPK1	S491	T496N	496	Missense	distal	5	no	13.748	13.749	EPSD	ICGC;COSMIC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	O75030	MITF	P28482	MAPK1	S491	D488G	488	Missense	distal	-3	no	13.748	13.688	EPSD	ICGC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	O75030	MITF	P28482	MAPK1	S491	L490F	490	Missense	proximal	-1	no	13.748	13.719	EPSD	ICGC;COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	O75030	MITF	P28482	MAPK1	S491	D497G	497	Missense	distal	6	no	13.748	13.716	EPSD	ICGC;COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	O75030	MITF	P28482	MAPK1	S504	G506R	506	Missense	proximal	2	no	14.819	14.914	EPSD	ICGC;COSMIC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	O75030	MITF	P28482	MAPK1	S504	S504C	504	Missense	central	0	yes	14.819	0.000	EPSD	ICGC;COSMIC	8.102	Loss
CMGC_MAPK_ERK1_MAPK1_ST	O75030	MITF	P28482	MAPK1	S504	S504P	504	Missense	central	0	yes	14.819	0.000	EPSD	ICGC	8.102	Loss
CMGC_MAPK_ERK1_MAPK1_ST	O75030	MITF	P28482	MAPK1	S504	D497G	497	Missense	distal	-7	no	14.819	14.804	EPSD	ICGC;COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	O75030	MITF	P28482	MAPK1	S504	L500F	500	Missense	distal	-4	no	14.819	14.779	EPSD	ICGC;COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	O75030	MITF	P28482	MAPK1	S511	G506R	506	Missense	distal	-5	no	9.061	9.041	EPSD	ICGC;COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	O75030	MITF	P28482	MAPK1	S511	S504C	504	Missense	distal	-7	no	9.061	9.028	EPSD	ICGC;COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	O75030	MITF	P28482	MAPK1	S511	S504P	504	Missense	distal	-7	no	9.061	9.065	EPSD	ICGC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	O75030	MITF	P28482	MAPK1	S511	R513Q	513	Missense	proximal	2	no	9.061	8.769	EPSD	ICGC;COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	O75030	MITF	P28482	MAPK1	S512	R513Q	513	Missense	proximal	1	no	7.732	8.893	EPSD	ICGC;COSMIC	8.102	Gain
CMGC_MAPK_ERK1_MAPK1_ST	O75030	MITF	P28482	MAPK1	S515	M519T	519	Missense	distal	4	no	8.809	8.884	EPSD	ICGC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	O75030	MITF	P28482	MAPK1	S515	R513Q	513	Missense	proximal	-2	no	8.809	7.634	EPSD	ICGC;COSMIC	8.102	Loss
CMGC_MAPK_ERK1_MAPK1_ST	O75030	MITF	P28482	MAPK1	S518	M519T	519	Missense	proximal	1	no	2.412	8.616	EPSD	ICGC	8.102	Gain
CMGC_MAPK_ERK1_MAPK1_ST	P03372	ESR1	P28482	MAPK1	S104	P99S	99	Missense	distal	-5	no	13.696	13.770	EPSD;PhosphoSitePlus	ICGC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P03372	ESR1	P28482	MAPK1	S104	S102N	102	Missense	proximal	-2	no	13.696	13.710	EPSD;PhosphoSitePlus	ICGC;COSMIC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P03372	ESR1	P28482	MAPK1	S104	N101S	101	Missense	distal	-3	no	13.696	13.681	EPSD;PhosphoSitePlus	ICGC;COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P03372	ESR1	P28482	MAPK1	S106	P99S	99	Missense	distal	-7	no	13.462	13.458	EPSD;PhosphoSitePlus	ICGC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P03372	ESR1	P28482	MAPK1	S106	S102N	102	Missense	distal	-4	no	13.462	13.503	EPSD;PhosphoSitePlus	ICGC;COSMIC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P03372	ESR1	P28482	MAPK1	S106	N101S	101	Missense	distal	-5	no	13.462	13.510	EPSD;PhosphoSitePlus	ICGC;COSMIC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P03372	ESR1	P28482	MAPK1	S106	H112P	112	Missense	distal	6	no	13.462	13.767	EPSD;PhosphoSitePlus	ICGC;COSMIC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P03372	ESR1	P28482	MAPK1	S118	H112P	112	Missense	distal	-6	no	12.971	13.046	PhosphoSitePlus;EPSD	ICGC;COSMIC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P03372	ESR1	P28482	MAPK1	S118	P114L	114	Missense	distal	-4	no	12.971	12.667	PhosphoSitePlus;EPSD	ICGC;COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P03372	ESR1	P28482	MAPK1	S167	E163Q	163	Missense	distal	-4	no	8.379	8.215	EPSD	ICGC;COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P03372	ESR1	P28482	MAPK1	S294	R300L	300	Missense	distal	6	no	14.197	13.898	EPSD	ICGC;COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P03372	ESR1	P28482	MAPK1	S294	R300S	300	Missense	distal	6	no	14.197	14.304	EPSD	ICGC;COSMIC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P03372	ESR1	P28482	MAPK1	S294	R300H	300	Missense	distal	6	no	14.197	13.999	EPSD	ICGC;COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P03372	ESR1	P28482	MAPK1	S575	S576L	576	Missense	proximal	1	no	7.706	8.291	EPSD	ICGC;COSMIC	8.102	Gain
CMGC_MAPK_ERK1_MAPK1_ST	P03372	ESR1	P28482	MAPK1	S576	S576L	576	Missense	central	0	yes	8.436	0.000	EPSD	ICGC;COSMIC	8.102	Loss
CMGC_MAPK_ERK1_MAPK1_ST	P09874	PARP1	P28482	MAPK1	T327	W333L	333	Missense	distal	6	no	9.732	10.355	EPSD	ICGC;COSMIC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P09874	PARP1	P28482	MAPK1	T335	E341Q	341	Missense	distal	6	no	14.092	13.771	EPSD	ICGC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P09874	PARP1	P28482	MAPK1	T335	R340Q	340	Missense	distal	5	no	14.092	13.922	EPSD	ICGC;COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P09874	PARP1	P28482	MAPK1	T335	W333L	333	Missense	proximal	-2	no	14.092	14.916	EPSD	ICGC;COSMIC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P09874	PARP1	P28482	MAPK1	T368	T368K	368	Missense	central	0	yes	13.208	0.000	EPSD	ICGC	8.102	Loss
CMGC_MAPK_ERK1_MAPK1_ST	P09874	PARP1	P28482	MAPK1	S372	T368K	368	Missense	distal	-4	no	8.983	9.286	PhosphoSitePlus;EPSD	ICGC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P09874	PARP1	P28482	MAPK1	T373	T368K	368	Missense	distal	-5	no	10.488	10.388	EPSD;PhosphoSitePlus	ICGC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P09874	PARP1	P28482	MAPK1	S479	V485L	485	Missense	distal	6	no	14.080	13.888	EPSD	ICGC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P09874	PARP1	P28482	MAPK1	S479	A475T	475	Missense	distal	-4	no	14.080	14.060	EPSD	ICGC;COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P09874	PARP1	P28482	MAPK1	S554	G558D	558	Missense	distal	4	no	8.342	8.294	EPSD	ICGC;COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q07889	SOS1	P28482	MAPK1	S582	R576S	576	Missense	distal	-6	no	9.039	9.005	EPSD	ICGC;COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q07889	SOS1	P28482	MAPK1	S582	N585T	585	Missense	distal	3	no	9.039	9.109	EPSD	ICGC;COSMIC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q07889	SOS1	P28482	MAPK1	S757	E762K	762	Missense	distal	5	no	15.597	15.537	EPSD	ICGC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q07889	SOS1	P28482	MAPK1	S757	P759H	759	Missense	proximal	2	no	15.597	15.467	EPSD	ICGC;COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q07889	SOS1	P28482	MAPK1	S818	E812K	812	Missense	distal	-6	no	14.069	14.043	EPSD	ICGC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q07889	SOS1	P28482	MAPK1	S1064	I1068N	1068	Missense	distal	4	no	8.454	8.583	EPSD	ICGC;COSMIC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q07889	SOS1	P28482	MAPK1	T1088	A1095D	1095	Missense	distal	7	no	14.309	14.124	EPSD	ICGC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q07889	SOS1	P28482	MAPK1	S1132	V1135I	1135	Missense	distal	3	no	10.454	10.524	EPSD;PhosphoSitePlus	ICGC;COSMIC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q07889	SOS1	P28482	MAPK1	S1132	P1130Q	1130	Missense	proximal	-2	no	10.454	7.460	EPSD;PhosphoSitePlus	ICGC	8.102	Loss
CMGC_MAPK_ERK1_MAPK1_ST	Q07889	SOS1	P28482	MAPK1	S1132	T1125N	1125	Missense	distal	-7	no	10.454	10.469	EPSD;PhosphoSitePlus	ICGC;COSMIC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q07889	SOS1	P28482	MAPK1	S1161	P1168T	1168	Missense	distal	7	no	9.015	9.178	EPSD	ICGC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q07889	SOS1	P28482	MAPK1	S1161	P1168R	1168	Missense	distal	7	no	9.015	9.030	EPSD	ICGC;COSMIC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q07889	SOS1	P28482	MAPK1	S1167	I1171S	1171	Missense	distal	4	no	14.128	14.294	EPSD;PhosphoSitePlus	ICGC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q07889	SOS1	P28482	MAPK1	S1167	P1168T	1168	Missense	proximal	1	no	14.128	5.629	EPSD;PhosphoSitePlus	ICGC	8.102	Loss
CMGC_MAPK_ERK1_MAPK1_ST	Q07889	SOS1	P28482	MAPK1	S1167	P1168R	1168	Missense	proximal	1	no	14.128	4.474	EPSD;PhosphoSitePlus	ICGC;COSMIC	8.102	Loss
CMGC_MAPK_ERK1_MAPK1_ST	Q07889	SOS1	P28482	MAPK1	S1178	I1171S	1171	Missense	distal	-7	no	13.573	13.600	EPSD;PhosphoSitePlus	ICGC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q07889	SOS1	P28482	MAPK1	S1193	A1191D	1191	Missense	proximal	-2	no	15.592	15.437	EPSD;PhosphoSitePlus	ICGC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q07889	SOS1	P28482	MAPK1	S1229	H1232N	1232	Missense	distal	3	no	14.269	14.171	EPSD	ICGC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q07889	SOS1	P28482	MAPK1	S1252	P1250T	1250	Missense	proximal	-2	no	17.483	14.784	EPSD	ICGC;COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q07889	SOS1	P28482	MAPK1	S1252	P1258T	1258	Missense	distal	6	no	17.483	17.273	EPSD	ICGC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q07889	SOS1	P28482	MAPK1	S1254	P1250T	1250	Missense	distal	-4	no	14.219	13.906	EPSD	ICGC;COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q07889	SOS1	P28482	MAPK1	S1254	P1258T	1258	Missense	distal	4	no	14.219	14.096	EPSD	ICGC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q07889	SOS1	P28482	MAPK1	T1257	P1250T	1250	Missense	distal	-7	no	15.601	15.584	EPSD	ICGC;COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q07889	SOS1	P28482	MAPK1	T1257	P1258T	1258	Missense	proximal	1	no	15.601	7.102	EPSD	ICGC	8.102	Loss
CMGC_MAPK_ERK1_MAPK1_ST	Q07889	SOS1	P28482	MAPK1	T1263	P1258T	1258	Missense	distal	-5	no	18.139	18.242	EPSD	ICGC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q07889	SOS1	P28482	MAPK1	S1265	P1258T	1258	Missense	distal	-7	no	15.480	15.463	EPSD	ICGC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q13614	MTMR2	P28482	MAPK1	S21	A28D	28	Missense	distal	7	no	8.628	8.443	EPSD	ICGC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q13614	MTMR2	P28482	MAPK1	S21	P14Q	14	Missense	distal	-7	no	8.628	8.631	EPSD	ICGC;COSMIC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q13614	MTMR2	P28482	MAPK1	S21	A28S	28	Missense	distal	7	no	8.628	8.447	EPSD	ICGC;COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q13614	MTMR2	P28482	MAPK1	S29	A28D	28	Missense	proximal	-1	no	8.462	8.444	EPSD	ICGC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q13614	MTMR2	P28482	MAPK1	S29	A28S	28	Missense	proximal	-1	no	8.462	8.456	EPSD	ICGC;COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q96EP5	DAZAP1	P28482	MAPK1	T86	D81N	81	Missense	distal	-5	no	15.831	15.787	EPSD	ICGC;COSMIC;GDSC;CCLE	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q96EP5	DAZAP1	P28482	MAPK1	T86	N79S	79	Missense	distal	-7	no	15.831	15.829	EPSD	ICGC;COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q96EP5	DAZAP1	P28482	MAPK1	T269	P271T	271	Missense	proximal	2	no	13.910	13.859	EPSD;PhosphoSitePlus	ICGC;COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q96EP5	DAZAP1	P28482	MAPK1	T269	S268Y	268	Missense	proximal	-1	no	13.910	13.878	EPSD;PhosphoSitePlus	ICGC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q96EP5	DAZAP1	P28482	MAPK1	T269	S264P	264	Missense	distal	-5	no	13.910	13.836	EPSD;PhosphoSitePlus	ICGC;COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q96EP5	DAZAP1	P28482	MAPK1	T315	A319G	319	Missense	distal	4	no	17.191	17.235	PhosphoSitePlus;EPSD	ICGC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q96EP5	DAZAP1	P28482	MAPK1	T315	A318V	318	Missense	distal	3	no	17.191	17.171	PhosphoSitePlus;EPSD	ICGC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q13322	GRB10	P28482	MAPK1	T23	D29V	29	Missense	distal	6	no	15.860	15.691	EPSD	ICGC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q13322	GRB10	P28482	MAPK1	T23	T23K	23	Missense	central	0	yes	15.860	0.000	EPSD	ICGC	8.102	Loss
CMGC_MAPK_ERK1_MAPK1_ST	Q13322	GRB10	P28482	MAPK1	T23	Q27L	27	Missense	distal	4	no	15.860	15.848	EPSD	ICGC;COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q13322	GRB10	P28482	MAPK1	S150	S150N	150	Missense	central	0	yes	16.768	0.000	PhosphoSitePlus;EPSD	ICGC;COSMIC	8.102	Loss
CMGC_MAPK_ERK1_MAPK1_ST	Q13322	GRB10	P28482	MAPK1	S150	S150R	150	Missense	central	0	yes	16.768	0.000	PhosphoSitePlus;EPSD	ICGC	8.102	Loss
CMGC_MAPK_ERK1_MAPK1_ST	Q13322	GRB10	P28482	MAPK1	T155	S150N	150	Missense	distal	-5	no	12.625	12.576	EPSD	ICGC;COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q13322	GRB10	P28482	MAPK1	T155	S150R	150	Missense	distal	-5	no	12.625	12.598	EPSD	ICGC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q13322	GRB10	P28482	MAPK1	S418	S418I	418	Missense	central	0	yes	16.613	0.000	EPSD	ICGC;COSMIC	8.102	Loss
CMGC_MAPK_ERK1_MAPK1_ST	Q13322	GRB10	P28482	MAPK1	S421	S426I	426	Missense	distal	5	no	8.588	8.271	EPSD	ICGC;COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q13322	GRB10	P28482	MAPK1	S421	S418I	418	Missense	distal	-3	no	8.588	8.324	EPSD	ICGC;COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q13322	GRB10	P28482	MAPK1	T422	S426I	426	Missense	distal	4	no	13.463	13.297	EPSD	ICGC;COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q13322	GRB10	P28482	MAPK1	T422	S418I	418	Missense	distal	-4	no	13.463	12.876	EPSD	ICGC;COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	O95600	KLF8	P28482	MAPK1	S48	A54V	54	Missense	distal	6	no	12.489	12.571	PhosphoSitePlus	ICGC;COSMIC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	O95600	KLF8	P28482	MAPK1	S48	T50I	50	Missense	proximal	2	no	12.489	12.369	PhosphoSitePlus	ICGC;COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	O95600	KLF8	P28482	MAPK1	S342	H348Y	348	Missense	distal	6	no	10.183	9.870	EPSD	ICGC;COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	O95600	KLF8	P28482	MAPK1	S342	R335L	335	Missense	distal	-7	no	10.183	10.176	EPSD	ICGC;COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P84022	SMAD3	P28482	MAPK1	T8	L15V	15	Missense	distal	7	no	15.702	15.697	EPSD	ICGC;COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P84022	SMAD3	P28482	MAPK1	S204	D201N	201	Missense	distal	-3	no	14.774	14.742	EPSD;PhosphoSitePlus	ICGC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P84022	SMAD3	P28482	MAPK1	S208	D201N	201	Missense	distal	-7	no	16.481	16.482	PhosphoSitePlus;EPSD	ICGC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P84022	SMAD3	P28482	MAPK1	S213	L219F	219	Missense	distal	6	no	19.707	19.673	EPSD;PhosphoSitePlus	ICGC;COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P84022	SMAD3	P28482	MAPK1	T412	G415V	415	Missense	distal	3	no	9.466	9.440	EPSD	ICGC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P84022	SMAD3	P28482	MAPK1	T412	L411F	411	Missense	proximal	-1	no	9.466	9.436	EPSD	ICGC;COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P84022	SMAD3	P28482	MAPK1	T412	L411I	411	Missense	proximal	-1	no	9.466	9.460	EPSD	ICGC;COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P84022	SMAD3	P28482	MAPK1	S416	S423T	423	Missense	distal	7	no	12.685	12.838	EPSD	ICGC;COSMIC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P84022	SMAD3	P28482	MAPK1	S416	S422F	422	Missense	distal	6	no	12.685	12.245	EPSD	ICGC;COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P84022	SMAD3	P28482	MAPK1	S416	G415V	415	Missense	proximal	-1	no	12.685	12.714	EPSD	ICGC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P84022	SMAD3	P28482	MAPK1	S416	S423N	423	Missense	distal	7	no	12.685	12.668	EPSD	ICGC;COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P84022	SMAD3	P28482	MAPK1	S416	L411F	411	Missense	distal	-5	no	12.685	12.699	EPSD	ICGC;COSMIC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P84022	SMAD3	P28482	MAPK1	S416	R420S	420	Missense	distal	4	no	12.685	12.708	EPSD	ICGC;COSMIC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P84022	SMAD3	P28482	MAPK1	S416	L411I	411	Missense	distal	-5	no	12.685	12.746	EPSD	ICGC;COSMIC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P84022	SMAD3	P28482	MAPK1	S422	S423T	423	Missense	proximal	1	no	7.996	8.892	EPSD	ICGC;COSMIC	8.102	Gain
CMGC_MAPK_ERK1_MAPK1_ST	Q96I25	RBM17	P28482	MAPK1	S48	R44M	44	Missense	distal	-4	no	8.317	7.941	EPSD	ICGC;COSMIC	8.102	Loss
CMGC_MAPK_ERK1_MAPK1_ST	Q96I25	RBM17	P28482	MAPK1	S48	A52S	52	Missense	distal	4	no	8.317	8.410	EPSD	ICGC;COSMIC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q96I25	RBM17	P28482	MAPK1	S48	S42N	42	Missense	distal	-6	no	8.317	8.321	EPSD	ICGC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q96I25	RBM17	P28482	MAPK1	T71	D65Y	65	Missense	distal	-6	no	14.334	14.170	EPSD;PhosphoSitePlus	ICGC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q96I25	RBM17	P28482	MAPK1	S85	G86W	86	Missense	proximal	1	no	6.375	9.064	EPSD	ICGC	8.102	Gain
CMGC_MAPK_ERK1_MAPK1_ST	Q96I25	RBM17	P28482	MAPK1	T179	S180Y	180	Missense	proximal	1	no	6.578	8.964	EPSD	ICGC;COSMIC	8.102	Gain
CMGC_MAPK_ERK1_MAPK1_ST	Q96I25	RBM17	P28482	MAPK1	S222	P220L	220	Missense	proximal	-2	no	17.979	16.061	PhosphoSitePlus;EPSD	ICGC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P12980	LYL1	P28482	MAPK1	S25	A27V	27	Missense	proximal	2	no	14.308	14.384	EPSD	ICGC;COSMIC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P12980	LYL1	P28482	MAPK1	S36	V42M	42	Missense	distal	6	no	17.074	16.856	PhosphoSitePlus	ICGC;COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P12980	LYL1	P28482	MAPK1	S52	R48Q	48	Missense	distal	-4	no	14.251	14.147	EPSD	ICGC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P12980	LYL1	P28482	MAPK1	S52	G50R	50	Missense	proximal	-2	no	14.251	15.626	EPSD	ICGC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P12980	LYL1	P28482	MAPK1	S52	S52L	52	Missense	central	0	yes	14.251	0.000	EPSD	ICGC	8.102	Loss
CMGC_MAPK_ERK1_MAPK1_ST	P12980	LYL1	P28482	MAPK1	S260	G259S	259	Missense	proximal	-1	no	16.315	16.326	EPSD	ICGC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P51812	RPS6KA3	P28482	MAPK1	S17	A22T	22	Missense	distal	5	no	16.340	16.426	EPSD	ICGC;COSMIC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P51812	RPS6KA3	P28482	MAPK1	S17	W10R	10	Missense	distal	-7	no	16.340	16.390	EPSD	ICGC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P51812	RPS6KA3	P28482	MAPK1	S17	S21I	21	Missense	distal	4	no	16.340	16.173	EPSD	ICGC;COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P51812	RPS6KA3	P28482	MAPK1	S227	T231P	231	Missense	distal	4	no	10.418	10.542	EPSD	ICGC;COSMIC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P51812	RPS6KA3	P28482	MAPK1	S227	Y226N	226	Missense	proximal	-1	no	10.418	10.499	EPSD	ICGC;COSMIC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P51812	RPS6KA3	P28482	MAPK1	T354	T348K	348	Missense	distal	-6	no	8.461	8.495	EPSD	ICGC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P51812	RPS6KA3	P28482	MAPK1	S369	P374H	374	Missense	distal	5	no	15.616	15.489	EPSD	ICGC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P51812	RPS6KA3	P28482	MAPK1	S369	P373Q	373	Missense	distal	4	no	15.616	15.508	EPSD	ICGC;COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P51812	RPS6KA3	P28482	MAPK1	S386	S386C	386	Missense	central	0	yes	8.307	0.000	EPSD	ICGC;COSMIC	8.102	Loss
CMGC_MAPK_ERK1_MAPK1_ST	P51812	RPS6KA3	P28482	MAPK1	S386	T391N	391	Missense	distal	5	no	8.307	8.308	EPSD	ICGC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P51812	RPS6KA3	P28482	MAPK1	T577	A582T	582	Missense	distal	5	no	15.244	15.330	EPSD	ICGC;COSMIC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P51812	RPS6KA3	P28482	MAPK1	T577	M576T	576	Missense	proximal	-1	no	15.244	15.252	EPSD	ICGC;COSMIC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P51812	RPS6KA3	P28482	MAPK1	T625	R632Q	632	Missense	distal	7	no	10.201	10.316	EPSD	ICGC;COSMIC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P51812	RPS6KA3	P28482	MAPK1	T625	E627D	627	Missense	proximal	2	no	10.201	10.252	EPSD	ICGC;COSMIC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P51812	RPS6KA3	P28482	MAPK1	S715	N713S	713	Missense	proximal	-2	no	14.509	14.494	EPSD	ICGC;COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P51812	RPS6KA3	P28482	MAPK1	T725	A727D	727	Missense	proximal	2	no	10.124	10.238	EPSD	ICGC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P08047	SP1	P28482	MAPK1	S59	S56A	56	Missense	distal	-3	no	13.407	13.216	PhosphoSitePlus;EPSD	ICGC;COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P08047	SP1	P28482	MAPK1	T117	S114Y	114	Missense	distal	-3	no	12.701	12.432	EPSD	ICGC;COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P08047	SP1	P28482	MAPK1	T117	T117I	117	Missense	central	0	yes	12.701	0.000	EPSD	ICGC	8.102	Loss
CMGC_MAPK_ERK1_MAPK1_ST	P08047	SP1	P28482	MAPK1	T278	T285M	285	Missense	distal	7	no	12.616	12.823	EPSD	ICGC;COSMIC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P08047	SP1	P28482	MAPK1	T453	T455R	455	Missense	proximal	2	no	12.721	12.885	EPSD;PhosphoSitePlus	ICGC;COSMIC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P08047	SP1	P28482	MAPK1	T453	I451V	451	Missense	proximal	-2	no	12.721	12.743	EPSD;PhosphoSitePlus	ICGC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P08047	SP1	P28482	MAPK1	S588	Q594E	594	Missense	distal	6	no	14.768	15.089	EPSD	ICGC;COSMIC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P08047	SP1	P28482	MAPK1	S588	Q592H	592	Missense	distal	4	no	14.768	14.701	EPSD	ICGC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P08047	SP1	P28482	MAPK1	S588	P589Q	589	Missense	proximal	1	no	14.768	6.274	EPSD	ICGC;COSMIC	8.102	Loss
CMGC_MAPK_ERK1_MAPK1_ST	P08047	SP1	P28482	MAPK1	T739	A738G	738	Missense	proximal	-1	no	13.402	13.385	EPSD;PhosphoSitePlus	ICGC;COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P55211	CASP9	P28482	MAPK1	S87	Q94K	94	Missense	distal	7	no	9.260	9.089	EPSD	ICGC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P55211	CASP9	P28482	MAPK1	S87	D83E	83	Missense	distal	-4	no	9.260	9.245	EPSD	ICGC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P55211	CASP9	P28482	MAPK1	S87	R90Q	90	Missense	distal	3	no	9.260	9.282	EPSD	ICGC;COSMIC;GDSC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P55211	CASP9	P28482	MAPK1	S87	Q82H	82	Missense	distal	-5	no	9.260	9.259	EPSD	ICGC;COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P55211	CASP9	P28482	MAPK1	T107	E114V	114	Missense	distal	7	no	14.563	14.905	EPSD	ICGC;COSMIC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P55211	CASP9	P28482	MAPK1	T107	P113Q	113	Missense	distal	6	no	14.563	14.276	EPSD	ICGC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P55211	CASP9	P28482	MAPK1	T125	L121I	121	Missense	distal	-4	no	15.221	14.855	PhosphoSitePlus	ICGC;COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P55211	CASP9	P28482	MAPK1	S302	S302F	302	Missense	central	0	yes	15.851	0.000	EPSD	ICGC	8.102	Loss
CMGC_MAPK_ERK1_MAPK1_ST	P55211	CASP9	P28482	MAPK1	S307	S302F	302	Missense	distal	-5	no	12.776	12.864	EPSD	ICGC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q16828	DUSP6	P28482	MAPK1	S159	S154L	154	Missense	distal	-5	no	13.542	13.617	PhosphoSitePlus;EPSD	ICGC;COSMIC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q16828	DUSP6	P28482	MAPK1	S159	D152E	152	Missense	distal	-7	no	13.542	13.550	PhosphoSitePlus;EPSD	ICGC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q16828	DUSP6	P28482	MAPK1	S197	P198Q	198	Missense	proximal	1	no	14.950	6.456	EPSD;PhosphoSitePlus	ICGC	8.102	Loss
CMGC_MAPK_ERK1_MAPK1_ST	Q16828	DUSP6	P28482	MAPK1	S205	P198Q	198	Missense	distal	-7	no	8.150	8.153	EPSD	ICGC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q16828	DUSP6	P28482	MAPK1	S351	E344K	344	Missense	distal	-7	no	15.140	15.133	EPSD	ICGC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q16828	DUSP6	P28482	MAPK1	S351	L347M	347	Missense	distal	-4	no	15.140	14.979	EPSD	ICGC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q16828	DUSP6	P28482	MAPK1	S351	D354N	354	Missense	distal	3	no	15.140	15.045	EPSD	ICGC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q16828	DUSP6	P28482	MAPK1	S351	T346M	346	Missense	distal	-5	no	15.140	15.190	EPSD	ICGC;COSMIC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q9Y6W5	WASF2	P28482	MAPK1	T129	P131S	131	Missense	proximal	2	no	12.926	12.898	EPSD	ICGC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q9Y6W5	WASF2	P28482	MAPK1	T137	P131S	131	Missense	distal	-6	no	12.338	12.312	EPSD	ICGC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q9Y6W5	WASF2	P28482	MAPK1	S257	P250S	250	Missense	distal	-7	no	14.282	14.277	EPSD	ICGC;COSMIC;CCLE	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q9Y6W5	WASF2	P28482	MAPK1	S259	N266T	266	Missense	distal	7	no	14.368	14.538	EPSD	ICGC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q9Y6W5	WASF2	P28482	MAPK1	S296	H299R	299	Missense	distal	3	no	16.752	16.709	EPSD;PhosphoSitePlus	ICGC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q9Y6W5	WASF2	P28482	MAPK1	S296	P301T	301	Missense	distal	5	no	16.752	16.696	EPSD;PhosphoSitePlus	ICGC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q9Y6W5	WASF2	P28482	MAPK1	S308	P301T	301	Missense	distal	-7	no	16.283	16.266	PhosphoSitePlus;EPSD	ICGC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q9Y6W5	WASF2	P28482	MAPK1	S308	G311C	311	Missense	distal	3	no	16.283	16.372	PhosphoSitePlus;EPSD	ICGC;COSMIC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q9Y6W5	WASF2	P28482	MAPK1	S343	P348L	348	Missense	distal	5	no	13.807	13.594	EPSD	ICGC;COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q9Y6W5	WASF2	P28482	MAPK1	S343	P337L	337	Missense	distal	-6	no	13.807	13.715	EPSD	ICGC;CCLE	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q9Y6W5	WASF2	P28482	MAPK1	T346	P348L	348	Missense	proximal	2	no	17.201	17.053	EPSD	ICGC;COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q9Y6W5	WASF2	P28482	MAPK1	S351	P348L	348	Missense	distal	-3	no	17.830	17.446	EPSD	ICGC;COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q9Y6W5	WASF2	P28482	MAPK1	S351	H358Q	358	Missense	distal	7	no	17.830	17.726	EPSD	ICGC;COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	O94953	KDM4B	P28482	MAPK1	T185	K183T	183	Missense	proximal	-2	no	8.535	8.255	EPSD	ICGC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	O94953	KDM4B	P28482	MAPK1	T185	F179L	179	Missense	distal	-6	no	8.535	8.553	EPSD	ICGC;COSMIC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	O94953	KDM4B	P28482	MAPK1	T305	K311N	311	Missense	distal	6	no	10.333	10.180	EPSD;PhosphoSitePlus	ICGC;COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	O94953	KDM4B	P28482	MAPK1	T305	D312N	312	Missense	distal	7	no	10.333	10.320	EPSD;PhosphoSitePlus	ICGC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	O94953	KDM4B	P28482	MAPK1	T305	R310W	310	Missense	distal	5	no	10.333	9.804	EPSD;PhosphoSitePlus	ICGC;COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	O94953	KDM4B	P28482	MAPK1	S352	L355P	355	Missense	distal	3	no	15.356	15.267	PhosphoSitePlus;EPSD	ICGC;COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	O94953	KDM4B	P28482	MAPK1	S352	A349E	349	Missense	distal	-3	no	15.356	15.544	PhosphoSitePlus;EPSD	ICGC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	O94953	KDM4B	P28482	MAPK1	S352	P353L	353	Missense	proximal	1	no	15.356	6.547	PhosphoSitePlus;EPSD	ICGC	8.102	Loss
CMGC_MAPK_ERK1_MAPK1_ST	O94953	KDM4B	P28482	MAPK1	S357	L355P	355	Missense	proximal	-2	no	6.701	8.618	EPSD	ICGC;COSMIC	8.102	Gain
CMGC_MAPK_ERK1_MAPK1_ST	O94953	KDM4B	P28482	MAPK1	S566	P573T	573	Missense	distal	7	no	17.766	17.929	EPSD;PhosphoSitePlus	ICGC;COSMIC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	O94953	KDM4B	P28482	MAPK1	S622	K628N	628	Missense	distal	6	no	15.025	14.872	EPSD;PhosphoSitePlus	ICGC;COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	O94953	KDM4B	P28482	MAPK1	S622	R617L	617	Missense	distal	-5	no	15.025	15.126	EPSD;PhosphoSitePlus	ICGC;COSMIC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	O94953	KDM4B	P28482	MAPK1	S622	L624M	624	Missense	proximal	2	no	15.025	14.981	EPSD;PhosphoSitePlus	ICGC;COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	O94953	KDM4B	P28482	MAPK1	T1065	A1068S	1068	Missense	distal	3	no	14.614	14.605	EPSD;PhosphoSitePlus	ICGC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	O94953	KDM4B	P28482	MAPK1	T1065	A1058S	1058	Missense	distal	-7	no	14.614	14.612	EPSD;PhosphoSitePlus	ICGC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q15788	NCOA1	P28482	MAPK1	S16	P23S	23	Missense	distal	7	no	12.301	12.312	EPSD	ICGC;COSMIC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q15788	NCOA1	P28482	MAPK1	S16	P14T	14	Missense	proximal	-2	no	12.301	9.602	EPSD	ICGC;COSMIC;CCLE	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q15788	NCOA1	P28482	MAPK1	S22	P23S	23	Missense	proximal	1	no	15.676	6.281	EPSD	ICGC;COSMIC	8.102	Loss
CMGC_MAPK_ERK1_MAPK1_ST	Q15788	NCOA1	P28482	MAPK1	S22	A28S	28	Missense	distal	6	no	15.676	15.972	EPSD	ICGC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q15788	NCOA1	P28482	MAPK1	S22	D25Y	25	Missense	distal	3	no	15.676	15.717	EPSD	ICGC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q15788	NCOA1	P28482	MAPK1	S395	R402P	402	Missense	distal	7	no	13.004	12.989	EPSD;PhosphoSitePlus	ICGC;COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q15788	NCOA1	P28482	MAPK1	S395	P388H	388	Missense	distal	-7	no	13.004	12.987	EPSD;PhosphoSitePlus	ICGC;COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q15788	NCOA1	P28482	MAPK1	S395	R402H	402	Missense	distal	7	no	13.004	13.223	EPSD;PhosphoSitePlus	ICGC;COSMIC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q15788	NCOA1	P28482	MAPK1	S517	I512V	512	Missense	distal	-5	no	15.224	15.111	EPSD	ICGC;COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q15788	NCOA1	P28482	MAPK1	S569	S571I	571	Missense	proximal	2	no	14.778	14.635	EPSD	ICGC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q15788	NCOA1	P28482	MAPK1	S698	E696D	696	Missense	proximal	-2	no	14.664	13.742	EPSD	ICGC;COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q15788	NCOA1	P28482	MAPK1	S698	D701Y	701	Missense	distal	3	no	14.664	14.705	EPSD	ICGC;COSMIC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q15788	NCOA1	P28482	MAPK1	T763	E757D	757	Missense	distal	-6	no	14.630	14.643	EPSD	ICGC;COSMIC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q15788	NCOA1	P28482	MAPK1	T789	P788Q	788	Missense	proximal	-1	no	14.030	13.989	EPSD	ICGC;COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q15788	NCOA1	P28482	MAPK1	T979	A978S	978	Missense	proximal	-1	no	12.582	12.575	EPSD	ICGC;COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q15788	NCOA1	P28482	MAPK1	T979	A978T	978	Missense	proximal	-1	no	12.582	12.576	EPSD	ICGC;COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q15788	NCOA1	P28482	MAPK1	S997	L1004F	1004	Missense	distal	7	no	15.203	15.262	EPSD	ICGC;COSMIC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q15788	NCOA1	P28482	MAPK1	S997	A1002S	1002	Missense	distal	5	no	15.203	15.363	EPSD	ICGC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q15788	NCOA1	P28482	MAPK1	S997	P998S	998	Missense	proximal	1	no	15.203	5.808	EPSD	ICGC	8.102	Loss
CMGC_MAPK_ERK1_MAPK1_ST	Q15788	NCOA1	P28482	MAPK1	S999	L1004F	1004	Missense	distal	5	no	14.126	14.160	EPSD	ICGC;COSMIC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q15788	NCOA1	P28482	MAPK1	S999	S1006I	1006	Missense	distal	7	no	14.126	14.674	EPSD	ICGC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q15788	NCOA1	P28482	MAPK1	S999	A1002S	1002	Missense	distal	3	no	14.126	14.117	EPSD	ICGC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q15788	NCOA1	P28482	MAPK1	S999	P998S	998	Missense	proximal	-1	no	14.126	14.083	EPSD	ICGC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q15788	NCOA1	P28482	MAPK1	S1006	L1004F	1004	Missense	proximal	-2	no	12.901	12.178	EPSD	ICGC;COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q15788	NCOA1	P28482	MAPK1	S1006	G1010C	1010	Missense	distal	4	no	12.901	12.669	EPSD	ICGC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q15788	NCOA1	P28482	MAPK1	S1006	M1011I	1011	Missense	distal	5	no	12.901	12.789	EPSD	ICGC;COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q15788	NCOA1	P28482	MAPK1	S1006	S1006I	1006	Missense	central	0	yes	12.901	0.000	EPSD	ICGC	8.102	Loss
CMGC_MAPK_ERK1_MAPK1_ST	Q15788	NCOA1	P28482	MAPK1	S1006	V1012F	1012	Missense	distal	6	no	12.901	12.675	EPSD	ICGC;COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q15788	NCOA1	P28482	MAPK1	S1006	A1002S	1002	Missense	distal	-4	no	12.901	13.111	EPSD	ICGC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q15788	NCOA1	P28482	MAPK1	S1006	G1010V	1010	Missense	distal	4	no	12.901	12.851	EPSD	ICGC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q15788	NCOA1	P28482	MAPK1	S1006	P1007S	1007	Missense	proximal	1	no	12.901	3.506	EPSD	ICGC	8.102	Loss
CMGC_MAPK_ERK1_MAPK1_ST	Q15788	NCOA1	P28482	MAPK1	T1026	Q1024E	1024	Missense	proximal	-2	no	14.567	15.181	EPSD	ICGC;COSMIC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q15788	NCOA1	P28482	MAPK1	T1026	T1020M	1020	Missense	distal	-6	no	14.567	14.533	EPSD	ICGC;COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q15788	NCOA1	P28482	MAPK1	T1026	P1027L	1027	Missense	proximal	1	no	14.567	5.757	EPSD	ICGC	8.102	Loss
CMGC_MAPK_ERK1_MAPK1_ST	Q15788	NCOA1	P28482	MAPK1	T1026	R1029Q	1029	Missense	distal	3	no	14.567	14.589	EPSD	ICGC;COSMIC;GDSC;CCLE	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q15788	NCOA1	P28482	MAPK1	S1033	P1027L	1027	Missense	distal	-6	no	13.749	13.657	EPSD	ICGC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q15788	NCOA1	P28482	MAPK1	S1033	G1035D	1035	Missense	proximal	2	no	13.749	13.715	EPSD	ICGC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q15788	NCOA1	P28482	MAPK1	S1033	R1029Q	1029	Missense	distal	-4	no	13.749	13.646	EPSD	ICGC;COSMIC;GDSC;CCLE	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q15788	NCOA1	P28482	MAPK1	T1099	G1093V	1093	Missense	distal	-6	no	11.503	11.460	EPSD	ICGC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q15788	NCOA1	P28482	MAPK1	T1099	P1102T	1102	Missense	distal	3	no	11.503	11.565	EPSD	ICGC;COSMIC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q15788	NCOA1	P28482	MAPK1	T1179	Y1173F	1173	Missense	distal	-6	no	16.029	16.059	PhosphoSitePlus;EPSD	ICGC;COSMIC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q15788	NCOA1	P28482	MAPK1	T1179	S1185C	1185	Missense	distal	6	no	16.029	15.162	PhosphoSitePlus;EPSD	ICGC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q15788	NCOA1	P28482	MAPK1	T1179	P1186S	1186	Missense	distal	7	no	16.029	16.040	PhosphoSitePlus;EPSD	ICGC;COSMIC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q15788	NCOA1	P28482	MAPK1	T1179	G1174C	1174	Missense	distal	-5	no	16.029	16.239	PhosphoSitePlus;EPSD	ICGC;COSMIC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q15788	NCOA1	P28482	MAPK1	S1185	S1185C	1185	Missense	central	0	yes	14.689	0.000	EPSD;PhosphoSitePlus	ICGC	8.102	Loss
CMGC_MAPK_ERK1_MAPK1_ST	Q15788	NCOA1	P28482	MAPK1	S1185	P1186S	1186	Missense	proximal	1	no	14.689	5.294	EPSD;PhosphoSitePlus	ICGC;COSMIC	8.102	Loss
CMGC_MAPK_ERK1_MAPK1_ST	Q15788	NCOA1	P28482	MAPK1	S1250	P1251S	1251	Missense	proximal	1	no	13.971	4.576	EPSD	ICGC	8.102	Loss
CMGC_MAPK_ERK1_MAPK1_ST	Q15788	NCOA1	P28482	MAPK1	S1250	L1249I	1249	Missense	proximal	-1	no	13.971	13.965	EPSD	ICGC;COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q15788	NCOA1	P28482	MAPK1	T1271	Q1278H	1278	Missense	distal	7	no	14.120	14.224	EPSD	ICGC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q15788	NCOA1	P28482	MAPK1	S1279	Q1278H	1278	Missense	proximal	-1	no	14.789	14.787	EPSD	ICGC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q15788	NCOA1	P28482	MAPK1	T1426	T1421M	1421	Missense	distal	-5	no	19.438	19.488	EPSD	ICGC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P13591	NCAM1	P28482	MAPK1	S613	A614S	614	Missense	proximal	1	no	8.222	6.458	EPSD	ICGC	8.102	Loss
CMGC_MAPK_ERK1_MAPK1_ST	P15923	TCF3	P28482	MAPK1	S110	G112W	112	Missense	proximal	2	no	9.107	8.834	EPSD	ICGC;COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P15923	TCF3	P28482	MAPK1	S110	Y108H	108	Missense	proximal	-2	no	9.107	8.470	EPSD	ICGC;COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P15923	TCF3	P28482	MAPK1	S110	G103C	103	Missense	distal	-7	no	9.107	9.089	EPSD	ICGC;COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P15923	TCF3	P28482	MAPK1	S134	G136W	136	Missense	proximal	2	no	14.698	14.425	EPSD	ICGC;COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P15923	TCF3	P28482	MAPK1	S139	P140S	140	Missense	proximal	1	no	18.181	8.786	EPSD	ICGC;CCLE	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P15923	TCF3	P28482	MAPK1	S139	G136W	136	Missense	distal	-3	no	18.181	17.652	EPSD	ICGC;COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P15923	TCF3	P28482	MAPK1	S139	K144Q	144	Missense	distal	5	no	18.181	18.146	EPSD	ICGC;COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P15923	TCF3	P28482	MAPK1	T205	A212V	212	Missense	distal	7	no	13.439	13.541	EPSD	ICGC;COSMIC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P15923	TCF3	P28482	MAPK1	S208	A212V	212	Missense	distal	4	no	9.363	9.357	EPSD	ICGC;COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P15923	TCF3	P28482	MAPK1	S229	P231Q	231	Missense	proximal	2	no	14.399	14.221	EPSD	ICGC;COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P15923	TCF3	P28482	MAPK1	S229	P231L	231	Missense	proximal	2	no	14.399	14.252	EPSD	ICGC;COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P15923	TCF3	P28482	MAPK1	S229	P231S	231	Missense	proximal	2	no	14.399	14.372	EPSD	ICGC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P15923	TCF3	P28482	MAPK1	S229	A234V	234	Missense	distal	5	no	14.399	14.416	EPSD	ICGC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P15923	TCF3	P28482	MAPK1	S245	P250L	250	Missense	distal	5	no	13.753	13.540	EPSD	ICGC;COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P15923	TCF3	P28482	MAPK1	S245	S245F	245	Missense	central	0	yes	13.753	0.000	EPSD	ICGC	8.102	Loss
CMGC_MAPK_ERK1_MAPK1_ST	P15923	TCF3	P28482	MAPK1	S245	L249P	249	Missense	distal	4	no	13.753	13.874	EPSD	ICGC;COSMIC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P15923	TCF3	P28482	MAPK1	T308	G302C	302	Missense	distal	-6	no	13.017	12.893	EPSD	ICGC;COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P15923	TCF3	P28482	MAPK1	T308	A314V	314	Missense	distal	6	no	13.017	13.098	EPSD	ICGC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P15923	TCF3	P28482	MAPK1	T308	G303S	303	Missense	distal	-5	no	13.017	13.023	EPSD	ICGC;COSMIC;CCLE	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P15923	TCF3	P28482	MAPK1	S352	S359C	359	Missense	distal	7	no	12.993	13.652	PhosphoSitePlus;EPSD	ICGC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P15923	TCF3	P28482	MAPK1	S352	S359F	359	Missense	distal	7	no	12.993	13.341	PhosphoSitePlus;EPSD	ICGC;COSMIC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P15923	TCF3	P28482	MAPK1	T355	S359C	359	Missense	distal	4	no	17.332	17.051	EPSD;PhosphoSitePlus	ICGC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P15923	TCF3	P28482	MAPK1	T355	S359F	359	Missense	distal	4	no	17.332	17.155	EPSD;PhosphoSitePlus	ICGC;COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P15923	TCF3	P28482	MAPK1	S359	S359C	359	Missense	central	0	yes	16.175	0.000	EPSD;PhosphoSitePlus	ICGC	8.102	Loss
CMGC_MAPK_ERK1_MAPK1_ST	P15923	TCF3	P28482	MAPK1	S359	S359F	359	Missense	central	0	yes	16.175	0.000	EPSD;PhosphoSitePlus	ICGC;COSMIC	8.102	Loss
CMGC_MAPK_ERK1_MAPK1_ST	P15923	TCF3	P28482	MAPK1	S379	D383Y	383	Missense	distal	4	no	13.460	13.363	EPSD	ICGC;COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P15923	TCF3	P28482	MAPK1	S379	L386I	386	Missense	distal	7	no	13.460	13.720	EPSD	ICGC;COSMIC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P15923	TCF3	P28482	MAPK1	S434	G441C	441	Missense	distal	7	no	7.661	8.252	EPSD	ICGC;COSMIC	8.102	Gain
CMGC_MAPK_ERK1_MAPK1_ST	P15923	TCF3	P28482	MAPK1	S529	A523P	523	Missense	distal	-6	no	15.759	15.798	EPSD	ICGC;COSMIC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P15923	TCF3	P28482	MAPK1	S529	D536E	536	Missense	distal	7	no	15.759	15.703	EPSD	ICGC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q96RK0	CIC	P28482	MAPK1	S12	R17C	17	Missense	distal	5	no	8.480	8.048	EPSD	ICGC;COSMIC	8.102	Loss
CMGC_MAPK_ERK1_MAPK1_ST	Q96RK0	CIC	P28482	MAPK1	S12	S12F	12	Missense	central	0	yes	8.480	0.000	EPSD	ICGC;COSMIC	8.102	Loss
CMGC_MAPK_ERK1_MAPK1_ST	Q96RK0	CIC	P28482	MAPK1	S13	R17C	17	Missense	distal	4	no	8.942	8.683	EPSD	ICGC;COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q96RK0	CIC	P28482	MAPK1	S13	S12F	12	Missense	proximal	-1	no	8.942	8.896	EPSD	ICGC;COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q96RK0	CIC	P28482	MAPK1	S317	V318F	318	Missense	proximal	1	no	6.192	9.163	EPSD	ICGC	8.102	Gain
CMGC_MAPK_ERK1_MAPK1_ST	Q96RK0	CIC	P28482	MAPK1	T393	P400H	400	Missense	distal	7	no	8.549	8.783	EPSD	ICGC;COSMIC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q96RK0	CIC	P28482	MAPK1	T583	G580C	580	Missense	distal	-3	no	16.950	16.435	EPSD	ICGC;COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q96RK0	CIC	P28482	MAPK1	S700	G695C	695	Missense	distal	-5	no	12.565	12.774	EPSD	ICGC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q96RK0	CIC	P28482	MAPK1	S700	R696L	696	Missense	distal	-4	no	12.565	12.350	EPSD	ICGC;COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q96RK0	CIC	P28482	MAPK1	S700	N702Y	702	Missense	proximal	2	no	12.565	12.445	EPSD	ICGC;COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q96RK0	CIC	P28482	MAPK1	T704	N702Y	702	Missense	proximal	-2	no	8.279	8.981	EPSD	ICGC;COSMIC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q96RK0	CIC	P28482	MAPK1	S739	S734L	734	Missense	distal	-5	no	12.857	12.931	EPSD	ICGC;COSMIC;GDSC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q96RK0	CIC	P28482	MAPK1	S894	Q901H	901	Missense	distal	7	no	8.842	8.946	EPSD	ICGC;COSMIC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q96RK0	CIC	P28482	MAPK1	S904	Q901H	901	Missense	distal	-3	no	15.460	15.408	EPSD	ICGC;COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q96RK0	CIC	P28482	MAPK1	S904	V903F	903	Missense	proximal	-1	no	15.460	15.397	EPSD	ICGC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q96RK0	CIC	P28482	MAPK1	S914	Q916H	916	Missense	proximal	2	no	8.312	8.360	EPSD	ICGC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q96RK0	CIC	P28482	MAPK1	S914	G920R	920	Missense	distal	6	no	8.312	8.282	EPSD	ICGC;COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q96RK0	CIC	P28482	MAPK1	S946	G939S	939	Missense	distal	-7	no	15.138	15.152	EPSD	ICGC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q96RK0	CIC	P28482	MAPK1	S946	G939A	939	Missense	distal	-7	no	15.138	15.154	EPSD	ICGC;COSMIC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q96RK0	CIC	P28482	MAPK1	T1145	P1139R	1139	Missense	distal	-6	no	13.675	13.683	EPSD	ICGC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q96RK0	CIC	P28482	MAPK1	S1173	Q1170R	1170	Missense	distal	-3	no	14.359	14.636	EPSD	ICGC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q96RK0	CIC	P28482	MAPK1	S1173	K1179N	1179	Missense	distal	6	no	14.359	14.206	EPSD	ICGC;COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q96RK0	CIC	P28482	MAPK1	S1173	R1171W	1171	Missense	proximal	-2	no	14.359	13.436	EPSD	ICGC;COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q96RK0	CIC	P28482	MAPK1	S1173	P1172A	1172	Missense	proximal	-1	no	14.359	14.322	EPSD	ICGC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q96RK0	CIC	P28482	MAPK1	S1173	P1167H	1167	Missense	distal	-6	no	14.359	14.285	EPSD	ICGC;COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q96RK0	CIC	P28482	MAPK1	S1191	S1186Y	1186	Missense	distal	-5	no	8.179	8.310	EPSD	ICGC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q96RK0	CIC	P28482	MAPK1	T1228	P1233S	1233	Missense	distal	5	no	14.763	14.781	EPSD	ICGC;COSMIC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q96RK0	CIC	P28482	MAPK1	T1228	Q1226K	1226	Missense	proximal	-2	no	14.763	15.337	EPSD	ICGC;COSMIC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q96RK0	CIC	P28482	MAPK1	T1238	W1239C	1239	Missense	proximal	1	no	8.879	2.808	EPSD	ICGC	8.102	Loss
CMGC_MAPK_ERK1_MAPK1_ST	Q96RK0	CIC	P28482	MAPK1	T1238	P1233S	1233	Missense	distal	-5	no	8.879	8.953	EPSD	ICGC;COSMIC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q96RK0	CIC	P28482	MAPK1	T1240	W1239C	1239	Missense	proximal	-1	no	13.602	13.601	EPSD	ICGC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q96RK0	CIC	P28482	MAPK1	T1240	P1233S	1233	Missense	distal	-7	no	13.602	13.598	EPSD	ICGC;COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q96RK0	CIC	P28482	MAPK1	S1246	W1239C	1239	Missense	distal	-7	no	16.144	16.163	EPSD	ICGC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q96RK0	CIC	P28482	MAPK1	T1291	R1286H	1286	Missense	distal	-5	no	17.146	17.223	EPSD	ICGC;COSMIC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q96RK0	CIC	P28482	MAPK1	S1373	P1372L	1372	Missense	proximal	-1	no	13.043	12.983	EPSD	ICGC;COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q96RK0	CIC	P28482	MAPK1	S1382	S1389F	1389	Missense	distal	7	no	14.115	14.462	EPSD	ICGC;COSMIC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q96RK0	CIC	P28482	MAPK1	S1409	R1415C	1415	Missense	distal	6	no	17.236	16.476	PhosphoSitePlus;EPSD	ICGC;COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q96RK0	CIC	P28482	MAPK1	S1595	Q1593P	1593	Missense	proximal	-2	no	16.271	19.265	EPSD	ICGC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q92793	CREBBP	P28482	MAPK1	S23	F30V	30	Missense	distal	7	no	9.036	8.971	EPSD	ICGC;COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q92793	CREBBP	P28482	MAPK1	S27	F30V	30	Missense	distal	3	no	8.129	8.054	EPSD	ICGC;COSMIC	8.102	Loss
CMGC_MAPK_ERK1_MAPK1_ST	Q92793	CREBBP	P28482	MAPK1	S93	N88D	88	Missense	distal	-5	no	13.467	13.512	PhosphoSitePlus	ICGC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q92793	CREBBP	P28482	MAPK1	S121	G126V	126	Missense	distal	5	no	12.427	12.303	EPSD	ICGC;COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q92793	CREBBP	P28482	MAPK1	S121	P122T	122	Missense	proximal	1	no	12.427	3.928	EPSD	ICGC;COSMIC	8.102	Loss
CMGC_MAPK_ERK1_MAPK1_ST	Q92793	CREBBP	P28482	MAPK1	S121	Q125H	125	Missense	distal	4	no	12.427	12.360	EPSD	ICGC;COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q92793	CREBBP	P28482	MAPK1	S121	S116I	116	Missense	distal	-5	no	12.427	12.562	EPSD	ICGC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q92793	CREBBP	P28482	MAPK1	S274	M267I	267	Missense	distal	-7	no	12.117	12.107	EPSD	ICGC;COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q92793	CREBBP	P28482	MAPK1	S281	Q286H	286	Missense	distal	5	no	8.264	8.257	EPSD	ICGC;COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q92793	CREBBP	P28482	MAPK1	S745	Q752K	752	Missense	distal	7	no	16.277	16.107	EPSD	ICGC;COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q92793	CREBBP	P28482	MAPK1	S1019	E1016K	1016	Missense	distal	-3	no	9.150	9.072	EPSD	ICGC;COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P32121	ARRB2	P28482	MAPK1	S360	P354S	354	Missense	distal	-6	no	11.077	11.050	EPSD	ICGC;COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q96RS0	TGS1	P28482	MAPK1	T168	R167S	167	Missense	proximal	-1	no	9.063	9.039	EPSD	ICGC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q96RS0	TGS1	P28482	MAPK1	S298	D303H	303	Missense	distal	5	no	18.074	17.904	PhosphoSitePlus	ICGC;COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q96RS0	TGS1	P28482	MAPK1	S298	N304I	304	Missense	distal	6	no	18.074	17.503	PhosphoSitePlus	ICGC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q96RS0	TGS1	P28482	MAPK1	S438	D439G	439	Missense	proximal	1	no	8.666	7.297	EPSD	ICGC;COSMIC	8.102	Loss
CMGC_MAPK_ERK1_MAPK1_ST	Q96RS0	TGS1	P28482	MAPK1	S438	G444V	444	Missense	distal	6	no	8.666	8.528	EPSD	ICGC;COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q96RS0	TGS1	P28482	MAPK1	S438	E434K	434	Missense	distal	-4	no	8.666	8.684	EPSD	ICGC;COSMIC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q96RS0	TGS1	P28482	MAPK1	S438	S445F	445	Missense	distal	7	no	8.666	9.013	EPSD	ICGC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q96RS0	TGS1	P28482	MAPK1	S578	Q574H	574	Missense	distal	-4	no	8.904	8.855	EPSD	ICGC;COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q96RS0	TGS1	P28482	MAPK1	S753	V760M	760	Missense	distal	7	no	8.145	8.222	EPSD	ICGC;COSMIC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q96RS0	TGS1	P28482	MAPK1	S753	D758Y	758	Missense	distal	5	no	8.145	7.831	EPSD	ICGC	8.102	Loss
CMGC_MAPK_ERK1_MAPK1_ST	Q96RS0	TGS1	P28482	MAPK1	S753	F754C	754	Missense	proximal	1	no	8.145	1.266	EPSD	ICGC	8.102	Loss
CMGC_MAPK_ERK1_MAPK1_ST	Q96RS0	TGS1	P28482	MAPK1	T839	G843C	843	Missense	distal	4	no	9.578	9.345	EPSD	ICGC;COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q01196	RUNX1	P28482	MAPK1	T18	M25V	25	Missense	distal	7	no	11.762	11.685	EPSD	ICGC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q01196	RUNX1	P28482	MAPK1	S21	M25V	25	Missense	distal	4	no	16.738	16.827	EPSD	ICGC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P49795	RGS19	P28482	MAPK1	S24	P20H	20	Missense	distal	-4	no	8.902	8.660	EPSD	ICGC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P49795	RGS19	P28482	MAPK1	S24	S22T	22	Missense	proximal	-2	no	8.902	9.036	EPSD	ICGC;COSMIC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P49795	RGS19	P28482	MAPK1	S24	D27H	27	Missense	distal	3	no	8.902	8.904	EPSD	ICGC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P49795	RGS19	P28482	MAPK1	S24	P21S	21	Missense	distal	-3	no	8.902	8.725	EPSD	ICGC;COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P49795	RGS19	P28482	MAPK1	S25	P20H	20	Missense	distal	-5	no	8.730	8.854	EPSD	ICGC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P49795	RGS19	P28482	MAPK1	S25	S22T	22	Missense	distal	-3	no	8.730	8.697	EPSD	ICGC;COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P49795	RGS19	P28482	MAPK1	S25	D27H	27	Missense	proximal	2	no	8.730	8.616	EPSD	ICGC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P49795	RGS19	P28482	MAPK1	S25	P21S	21	Missense	distal	-4	no	8.730	8.646	EPSD	ICGC;COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P49795	RGS19	P28482	MAPK1	T28	S22T	22	Missense	distal	-6	no	8.654	8.630	EPSD	ICGC;COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P49795	RGS19	P28482	MAPK1	T28	D27H	27	Missense	proximal	-1	no	8.654	8.667	EPSD	ICGC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P49795	RGS19	P28482	MAPK1	T28	P21S	21	Missense	distal	-7	no	8.654	8.650	EPSD	ICGC;COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P49795	RGS19	P28482	MAPK1	S30	R36H	36	Missense	distal	6	no	15.979	15.781	EPSD	ICGC;COSMIC;GDSC;CCLE	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P49795	RGS19	P28482	MAPK1	S30	R36C	36	Missense	distal	6	no	15.979	15.219	EPSD	ICGC;COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P49795	RGS19	P28482	MAPK1	S30	D27H	27	Missense	distal	-3	no	15.979	15.758	EPSD	ICGC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P49795	RGS19	P28482	MAPK1	T78	E83G	83	Missense	distal	5	no	13.115	13.140	EPSD	ICGC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P49795	RGS19	P28482	MAPK1	S80	E83G	83	Missense	distal	3	no	14.355	14.448	EPSD	ICGC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P49795	RGS19	P28482	MAPK1	S97	P98Q	98	Missense	proximal	1	no	11.333	2.840	EPSD	ICGC	8.102	Loss
CMGC_MAPK_ERK1_MAPK1_ST	P49795	RGS19	P28482	MAPK1	S151	P152H	152	Missense	proximal	1	no	15.124	7.300	PhosphoSitePlus	ICGC;COSMIC	8.102	Loss
CMGC_MAPK_ERK1_MAPK1_ST	P49795	RGS19	P28482	MAPK1	S199	R203C	203	Missense	distal	4	no	17.265	17.006	EPSD	ICGC;COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P49795	RGS19	P28482	MAPK1	S199	L205M	205	Missense	distal	6	no	17.265	17.238	EPSD	ICGC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P49795	RGS19	P28482	MAPK1	S199	P194S	194	Missense	distal	-5	no	17.265	17.339	EPSD	ICGC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P49795	RGS19	P28482	MAPK1	T201	R203C	203	Missense	proximal	2	no	9.580	9.207	EPSD	ICGC;COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P49795	RGS19	P28482	MAPK1	T201	Q208H	208	Missense	distal	7	no	9.580	9.684	EPSD	ICGC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P49795	RGS19	P28482	MAPK1	T201	L205M	205	Missense	distal	4	no	9.580	9.502	EPSD	ICGC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P49795	RGS19	P28482	MAPK1	T201	P194S	194	Missense	distal	-7	no	9.580	9.576	EPSD	ICGC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q8NHW3	MAFA	P28482	MAPK1	S49	S56N	56	Missense	distal	7	no	9.940	9.923	EPSD	ICGC;COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q8NHW3	MAFA	P28482	MAPK1	S49	S52L	52	Missense	distal	3	no	9.940	9.960	EPSD	ICGC;COSMIC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q8NHW3	MAFA	P28482	MAPK1	T53	S56N	56	Missense	distal	3	no	12.466	12.388	EPSD	ICGC;COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q8NHW3	MAFA	P28482	MAPK1	T53	S52L	52	Missense	proximal	-1	no	12.466	12.450	EPSD	ICGC;COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q8NHW3	MAFA	P28482	MAPK1	T57	S56N	56	Missense	proximal	-1	no	14.890	14.939	EPSD	ICGC;COSMIC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q8NHW3	MAFA	P28482	MAPK1	T57	S52L	52	Missense	distal	-5	no	14.890	14.965	EPSD	ICGC;COSMIC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q8NHW3	MAFA	P28482	MAPK1	S325	G328R	328	Missense	distal	3	no	9.518	9.480	EPSD	ICGC;COSMIC;GDSC;CCLE	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q9BUB5	MKNK1	P28482	MAPK1	T385	K381N	381	Missense	distal	-4	no	13.507	13.475	EPSD	ICGC;COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q96FF9	CDCA5	P28482	MAPK1	S21	R18S	18	Missense	distal	-3	no	16.770	16.613	EPSD	ICGC;COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q96FF9	CDCA5	P28482	MAPK1	S21	P20T	20	Missense	proximal	-1	no	16.770	16.728	EPSD	ICGC;COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q96FF9	CDCA5	P28482	MAPK1	T48	P49H	49	Missense	proximal	1	no	16.329	8.505	EPSD	ICGC;COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q96FF9	CDCA5	P28482	MAPK1	S75	P71S	71	Missense	distal	-4	no	15.275	15.191	EPSD	ICGC;COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q96FF9	CDCA5	P28482	MAPK1	S75	V70I	70	Missense	distal	-5	no	15.275	15.388	EPSD	ICGC;COSMIC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q96FF9	CDCA5	P28482	MAPK1	S79	S83F	83	Missense	distal	4	no	13.946	13.769	EPSD;PhosphoSitePlus	ICGC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q96FF9	CDCA5	P28482	MAPK1	S83	S83F	83	Missense	central	0	yes	8.129	0.000	EPSD	ICGC	8.102	Loss
CMGC_MAPK_ERK1_MAPK1_ST	Q96FF9	CDCA5	P28482	MAPK1	T111	T105K	105	Missense	distal	-6	no	16.339	16.374	EPSD	ICGC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q96FF9	CDCA5	P28482	MAPK1	T159	R163Q	163	Missense	distal	4	no	11.368	11.294	EPSD	ICGC;COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q96FF9	CDCA5	P28482	MAPK1	T159	R162S	162	Missense	distal	3	no	11.368	11.392	EPSD	ICGC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q96FF9	CDCA5	P28482	MAPK1	S209	I208S	208	Missense	proximal	-1	no	12.164	12.187	PhosphoSitePlus;EPSD	ICGC;COSMIC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q96FF9	CDCA5	P28482	MAPK1	S209	T204N	204	Missense	distal	-5	no	12.164	12.087	PhosphoSitePlus;EPSD	ICGC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q96FF9	CDCA5	P28482	MAPK1	S209	P211Q	211	Missense	proximal	2	no	12.164	11.986	PhosphoSitePlus;EPSD	ICGC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q96FF9	CDCA5	P28482	MAPK1	S209	P211T	211	Missense	proximal	2	no	12.164	12.114	PhosphoSitePlus;EPSD	ICGC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q96FF9	CDCA5	P28482	MAPK1	S209	Q215K	215	Missense	distal	6	no	12.164	12.509	PhosphoSitePlus;EPSD	ICGC;COSMIC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P49137	MAPKAPK2	P28482	MAPK1	T214	T215P	215	Missense	proximal	1	no	4.757	13.255	EPSD	ICGC;COSMIC	8.102	Gain
CMGC_MAPK_ERK1_MAPK1_ST	P49137	MAPKAPK2	P28482	MAPK1	T222	S216G	216	Missense	distal	-6	no	17.205	17.188	EPSD;PhosphoSitePlus	ICGC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P49137	MAPKAPK2	P28482	MAPK1	T222	T215P	215	Missense	distal	-7	no	17.205	17.222	EPSD;PhosphoSitePlus	ICGC;COSMIC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P49137	MAPKAPK2	P28482	MAPK1	T226	V230E	230	Missense	distal	4	no	11.594	11.667	EPSD	ICGC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P49137	MAPKAPK2	P28482	MAPK1	T334	P332H	332	Missense	proximal	-2	no	15.495	12.740	EPSD;PhosphoSitePlus	ICGC;COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P23396	RPS3	P28482	MAPK1	T42	R45S	45	Missense	distal	3	no	15.923	15.947	PhosphoSitePlus	ICGC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P23396	RPS3	P28482	MAPK1	T42	R40Q	40	Missense	proximal	-2	no	15.923	14.748	PhosphoSitePlus	ICGC;COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P23396	RPS3	P28482	MAPK1	T42	G36R	36	Missense	distal	-6	no	15.923	15.975	PhosphoSitePlus	ICGC;COSMIC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q5JQC9	AKAP4	P28482	MAPK1	S364	K359N	359	Missense	distal	-5	no	8.230	8.253	EPSD	ICGC;COSMIC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q5JQC9	AKAP4	P28482	MAPK1	S364	V370A	370	Missense	distal	6	no	8.230	8.148	EPSD	ICGC;COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q5JQC9	AKAP4	P28482	MAPK1	S808	S808R	808	Missense	central	0	yes	8.473	0.000	EPSD	ICGC;COSMIC	8.102	Loss
CMGC_MAPK_ERK1_MAPK1_ST	P17861	XBP1	P28482	MAPK1	T14	A7T	7	Missense	distal	-7	no	15.259	15.244	EPSD	ICGC;COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P17861	XBP1	P28482	MAPK1	T14	P15R	15	Missense	proximal	1	no	15.259	5.604	EPSD	ICGC;COSMIC	8.102	Loss
CMGC_MAPK_ERK1_MAPK1_ST	P17861	XBP1	P28482	MAPK1	T14	L19F	19	Missense	distal	5	no	15.259	15.293	EPSD	ICGC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P17861	XBP1	P28482	MAPK1	S47	Q43E	43	Missense	distal	-4	no	14.397	14.561	EPSD	ICGC;COSMIC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P17861	XBP1	P28482	MAPK1	S47	R44G	44	Missense	distal	-3	no	14.397	14.228	EPSD	ICGC;COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P17861	XBP1	P28482	MAPK1	S68	K72R	72	Missense	distal	4	no	13.013	13.003	PhosphoSitePlus;EPSD	ICGC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P17861	XBP1	P28482	MAPK1	S68	Q62L	62	Missense	distal	-6	no	13.013	12.936	PhosphoSitePlus;EPSD	ICGC;COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P17861	XBP1	P28482	MAPK1	S68	R75M	75	Missense	distal	7	no	13.013	13.369	PhosphoSitePlus;EPSD	ICGC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P17861	XBP1	P28482	MAPK1	S68	S68R	68	Missense	central	0	yes	13.013	0.000	PhosphoSitePlus;EPSD	ICGC	8.102	Loss
CMGC_MAPK_ERK1_MAPK1_ST	P17861	XBP1	P28482	MAPK1	S68	E71K	71	Missense	distal	3	no	13.013	13.019	PhosphoSitePlus;EPSD	ICGC;COSMIC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P17861	XBP1	P28482	MAPK1	S68	L74P	74	Missense	distal	6	no	13.013	13.419	PhosphoSitePlus;EPSD	ICGC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P17861	XBP1	P28482	MAPK1	S68	R61Q	61	Missense	distal	-7	no	13.013	13.021	PhosphoSitePlus;EPSD	ICGC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P17861	XBP1	P28482	MAPK1	S68	E71D	71	Missense	distal	3	no	13.013	13.108	PhosphoSitePlus;EPSD	ICGC;COSMIC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P17861	XBP1	P28482	MAPK1	S181	Q174R	174	Missense	distal	-7	no	15.050	15.042	EPSD;PhosphoSitePlus	ICGC;COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P17861	XBP1	P28482	MAPK1	S181	A178D	178	Missense	distal	-3	no	15.050	15.288	EPSD;PhosphoSitePlus	ICGC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P17861	XBP1	P28482	MAPK1	S181	P182H	182	Missense	proximal	1	no	15.050	7.226	EPSD;PhosphoSitePlus	ICGC	8.102	Loss
CMGC_MAPK_ERK1_MAPK1_ST	P17861	XBP1	P28482	MAPK1	S181	S187F	187	Missense	distal	6	no	15.050	14.609	EPSD;PhosphoSitePlus	ICGC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P17861	XBP1	P28482	MAPK1	S181	A178S	178	Missense	distal	-3	no	15.050	15.240	EPSD;PhosphoSitePlus	ICGC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P17861	XBP1	P28482	MAPK1	S255	H252Y	252	Missense	distal	-3	no	9.637	9.541	EPSD	ICGC;COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q8IZP0	ABI1	P28482	MAPK1	S22	A18E	18	Missense	distal	-4	no	9.403	9.667	EPSD	ICGC;COSMIC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q8IZP0	ABI1	P28482	MAPK1	S183	P176L	176	Missense	distal	-7	no	18.918	18.906	EPSD;PhosphoSitePlus	ICGC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q8IZP0	ABI1	P28482	MAPK1	S410	P411T	411	Missense	proximal	1	no	14.946	6.447	PhosphoSitePlus;EPSD	ICGC;COSMIC	8.102	Loss
CMGC_MAPK_ERK1_MAPK1_ST	P35658	NUP214	P28482	MAPK1	S30	P31R	31	Missense	proximal	1	no	14.354	4.700	EPSD	ICGC	8.102	Loss
CMGC_MAPK_ERK1_MAPK1_ST	P35658	NUP214	P28482	MAPK1	S201	L207P	207	Missense	distal	6	no	13.850	14.257	EPSD	ICGC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P35658	NUP214	P28482	MAPK1	S268	V272L	272	Missense	distal	4	no	14.061	14.050	EPSD	ICGC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P35658	NUP214	P28482	MAPK1	S268	P269Q	269	Missense	proximal	1	no	14.061	5.567	EPSD	ICGC;COSMIC	8.102	Loss
CMGC_MAPK_ERK1_MAPK1_ST	P35658	NUP214	P28482	MAPK1	T437	A443T	443	Missense	distal	6	no	14.442	14.528	EPSD	ICGC;COSMIC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P35658	NUP214	P28482	MAPK1	S462	A468S	468	Missense	distal	6	no	15.877	16.174	EPSD	ICGC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P35658	NUP214	P28482	MAPK1	S462	S457C	457	Missense	distal	-5	no	15.877	16.081	EPSD	ICGC;COSMIC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P35658	NUP214	P28482	MAPK1	T469	G476C	476	Missense	distal	7	no	7.779	8.370	EPSD	ICGC;COSMIC	8.102	Gain
CMGC_MAPK_ERK1_MAPK1_ST	P35658	NUP214	P28482	MAPK1	S483	K490N	490	Missense	distal	7	no	8.551	8.585	EPSD	ICGC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P35658	NUP214	P28482	MAPK1	S483	G476C	476	Missense	distal	-7	no	8.551	8.532	EPSD	ICGC;COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P35658	NUP214	P28482	MAPK1	S501	S508I	508	Missense	distal	7	no	10.542	11.090	EPSD	ICGC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P35658	NUP214	P28482	MAPK1	T519	P515S	515	Missense	distal	-4	no	10.270	10.186	EPSD	ICGC;COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P35658	NUP214	P28482	MAPK1	T533	P532L	532	Missense	proximal	-1	no	13.509	13.450	EPSD	ICGC;GDSC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P35658	NUP214	P28482	MAPK1	S537	P532L	532	Missense	distal	-5	no	13.011	13.160	EPSD	ICGC;GDSC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P35658	NUP214	P28482	MAPK1	S547	S545L	545	Missense	proximal	-2	no	7.922	8.839	EPSD	ICGC;COSMIC;GDSC	8.102	Gain
CMGC_MAPK_ERK1_MAPK1_ST	P35658	NUP214	P28482	MAPK1	T598	A594T	594	Missense	distal	-4	no	14.059	14.039	EPSD	ICGC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P35658	NUP214	P28482	MAPK1	S625	P629L	629	Missense	distal	4	no	9.113	8.993	EPSD	ICGC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P35658	NUP214	P28482	MAPK1	T628	S635I	635	Missense	distal	7	no	13.864	14.412	EPSD	ICGC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P35658	NUP214	P28482	MAPK1	T628	P629L	629	Missense	proximal	1	no	13.864	5.055	EPSD	ICGC	8.102	Loss
CMGC_MAPK_ERK1_MAPK1_ST	P35658	NUP214	P28482	MAPK1	S631	V637A	637	Missense	distal	6	no	8.602	8.520	EPSD	ICGC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P35658	NUP214	P28482	MAPK1	S631	S635I	635	Missense	distal	4	no	8.602	8.436	EPSD	ICGC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P35658	NUP214	P28482	MAPK1	S631	P629L	629	Missense	proximal	-2	no	8.602	6.685	EPSD	ICGC	8.102	Loss
CMGC_MAPK_ERK1_MAPK1_ST	P35658	NUP214	P28482	MAPK1	S636	V637A	637	Missense	proximal	1	no	6.717	8.627	EPSD	ICGC	8.102	Gain
CMGC_MAPK_ERK1_MAPK1_ST	P35658	NUP214	P28482	MAPK1	T1134	A1138T	1138	Missense	distal	4	no	15.121	15.102	EPSD	ICGC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P35658	NUP214	P28482	MAPK1	T1150	Y1145F	1145	Missense	distal	-5	no	13.990	13.947	EPSD	ICGC;COSMIC;GDSC;CCLE	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P35658	NUP214	P28482	MAPK1	T1178	A1180T	1180	Missense	proximal	2	no	9.949	10.029	EPSD	ICGC;COSMIC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P35658	NUP214	P28482	MAPK1	T1178	A1180S	1180	Missense	proximal	2	no	9.949	10.051	EPSD	ICGC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P35658	NUP214	P28482	MAPK1	S1272	G1276E	1276	Missense	distal	4	no	13.561	13.583	EPSD	ICGC;COSMIC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P35658	NUP214	P28482	MAPK1	S1809	G1816D	1816	Missense	distal	7	no	12.938	12.865	PhosphoSitePlus;EPSD	ICGC;COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P35658	NUP214	P28482	MAPK1	S1809	A1803T	1803	Missense	distal	-6	no	12.938	12.927	PhosphoSitePlus;EPSD	ICGC;COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P35658	NUP214	P28482	MAPK1	S1809	P1804H	1804	Missense	distal	-5	no	12.938	13.062	PhosphoSitePlus;EPSD	ICGC;COSMIC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P35658	NUP214	P28482	MAPK1	S1963	G1969V	1969	Missense	distal	6	no	14.348	14.210	EPSD	ICGC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P35658	NUP214	P28482	MAPK1	S1978	G1977V	1977	Missense	proximal	-1	no	13.644	13.672	EPSD	ICGC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P35658	NUP214	P28482	MAPK1	S1978	P1980H	1980	Missense	proximal	2	no	13.644	13.514	EPSD	ICGC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P35658	NUP214	P28482	MAPK1	T1981	G1977V	1977	Missense	distal	-4	no	9.108	9.104	EPSD	ICGC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P35658	NUP214	P28482	MAPK1	T1981	P1980H	1980	Missense	proximal	-1	no	9.108	9.066	EPSD	ICGC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P35658	NUP214	P28482	MAPK1	S1985	P1980H	1980	Missense	distal	-5	no	12.287	12.412	EPSD	ICGC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P35658	NUP214	P28482	MAPK1	S2002	G2008A	2008	Missense	distal	6	no	13.857	13.638	EPSD	ICGC;COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q15672	TWIST1	P28482	MAPK1	S68	Q71R	71	Missense	distal	3	no	16.330	16.308	PhosphoSitePlus	ICGC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q15672	TWIST1	P28482	MAPK1	S68	P66L	66	Missense	proximal	-2	no	16.330	14.413	PhosphoSitePlus	ICGC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q15672	TWIST1	P28482	MAPK1	S68	G67A	67	Missense	proximal	-1	no	16.330	16.347	PhosphoSitePlus	ICGC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q15672	TWIST1	P28482	MAPK1	S99	G92S	92	Missense	distal	-7	no	12.934	12.948	EPSD	ICGC;COSMIC;CCLE	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q15672	TWIST1	P28482	MAPK1	S99	S93G	93	Missense	distal	-6	no	12.934	12.917	EPSD	ICGC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q15672	TWIST1	P28482	MAPK1	S99	S95G	95	Missense	distal	-4	no	12.934	12.668	EPSD	ICGC;COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q15672	TWIST1	P28482	MAPK1	S102	S95G	95	Missense	distal	-7	no	9.723	9.710	EPSD	ICGC;COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q15796	SMAD2	P28482	MAPK1	T8	P9Q	9	Missense	proximal	1	no	15.387	6.893	EPSD	ICGC	8.102	Loss
CMGC_MAPK_ERK1_MAPK1_ST	Q15796	SMAD2	P28482	MAPK1	T8	F7L	7	Missense	proximal	-1	no	15.387	15.416	EPSD	ICGC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q15796	SMAD2	P28482	MAPK1	S21	A22D	22	Missense	proximal	1	no	8.307	7.241	EPSD	ICGC	8.102	Loss
CMGC_MAPK_ERK1_MAPK1_ST	Q15796	SMAD2	P28482	MAPK1	T172	P173Q	173	Missense	proximal	1	no	12.938	4.444	EPSD	ICGC;COSMIC	8.102	Loss
CMGC_MAPK_ERK1_MAPK1_ST	Q15796	SMAD2	P28482	MAPK1	T220	T220K	220	Missense	central	0	yes	12.681	0.000	EPSD;PhosphoSitePlus	ICGC	8.102	Loss
CMGC_MAPK_ERK1_MAPK1_ST	Q15796	SMAD2	P28482	MAPK1	S250	V257F	257	Missense	distal	7	no	16.438	16.503	EPSD;PhosphoSitePlus	ICGC;COSMIC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q15796	SMAD2	P28482	MAPK1	S255	V257F	257	Missense	proximal	2	no	16.866	16.760	PhosphoSitePlus;EPSD	ICGC;COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P01100	FOS	P28482	MAPK1	S32	S26I	26	Missense	distal	-6	no	15.127	15.026	EPSD	ICGC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P01100	FOS	P28482	MAPK1	S133	G127C	127	Missense	distal	-6	no	13.006	12.883	EPSD	ICGC;COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P01100	FOS	P28482	MAPK1	S133	P134Q	134	Missense	proximal	1	no	13.006	4.513	EPSD	ICGC;COSMIC	8.102	Loss
CMGC_MAPK_ERK1_MAPK1_ST	Q14674	ESPL1	P28482	MAPK1	S244	L242F	242	Missense	proximal	-2	no	15.686	14.962	EPSD	ICGC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q14674	ESPL1	P28482	MAPK1	S244	A248T	248	Missense	distal	4	no	15.686	15.666	EPSD	ICGC;COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q14674	ESPL1	P28482	MAPK1	S244	L243I	243	Missense	proximal	-1	no	15.686	15.680	EPSD	ICGC;COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q14674	ESPL1	P28482	MAPK1	S244	R247K	247	Missense	distal	3	no	15.686	15.637	EPSD	ICGC;COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q14674	ESPL1	P28482	MAPK1	S330	L333I	333	Missense	distal	3	no	13.223	13.261	EPSD	ICGC;COSMIC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q14674	ESPL1	P28482	MAPK1	S1153	S1149L	1149	Missense	distal	-4	no	13.426	13.206	EPSD	ICGC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q14674	ESPL1	P28482	MAPK1	T1210	N1207Y	1207	Missense	distal	-3	no	14.034	13.749	EPSD	ICGC;COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q14674	ESPL1	P28482	MAPK1	S1325	R1320H	1320	Missense	distal	-5	no	8.033	8.110	EPSD	ICGC;COSMIC	8.102	Gain
CMGC_MAPK_ERK1_MAPK1_ST	Q14674	ESPL1	P28482	MAPK1	T1346	G1340S	1340	Missense	distal	-6	no	16.955	16.972	EPSD	ICGC;COSMIC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q14674	ESPL1	P28482	MAPK1	S1406	D1403G	1403	Missense	distal	-3	no	8.549	8.489	EPSD	ICGC;COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q14674	ESPL1	P28482	MAPK1	S1406	E1402D	1402	Missense	distal	-4	no	8.549	8.563	EPSD	ICGC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q14674	ESPL1	P28482	MAPK1	S1406	A1409T	1409	Missense	distal	3	no	8.549	8.533	EPSD	ICGC;COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q14674	ESPL1	P28482	MAPK1	S1406	L1411Q	1411	Missense	distal	5	no	8.549	8.642	EPSD	ICGC;COSMIC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q14674	ESPL1	P28482	MAPK1	S1444	S1444N	1444	Missense	central	0	yes	8.363	0.000	EPSD	ICGC;COSMIC	8.102	Loss
CMGC_MAPK_ERK1_MAPK1_ST	Q14674	ESPL1	P28482	MAPK1	S1444	P1442Q	1442	Missense	proximal	-2	no	8.363	5.369	EPSD	ICGC;COSMIC	8.102	Loss
CMGC_MAPK_ERK1_MAPK1_ST	Q14674	ESPL1	P28482	MAPK1	S1545	K1550M	1550	Missense	distal	5	no	12.245	12.144	EPSD	ICGC;COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q14674	ESPL1	P28482	MAPK1	S1545	K1541Q	1541	Missense	distal	-4	no	12.245	12.063	EPSD	ICGC;COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q14674	ESPL1	P28482	MAPK1	S1545	S1539I	1539	Missense	distal	-6	no	12.245	12.144	EPSD	ICGC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q14674	ESPL1	P28482	MAPK1	S1545	S1538F	1538	Missense	distal	-7	no	12.245	12.225	EPSD	ICGC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q14674	ESPL1	P28482	MAPK1	S2118	V2117F	2117	Missense	proximal	-1	no	8.539	8.475	EPSD	ICGC;COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P19878	NCF2	P28482	MAPK1	T233	F237L	237	Missense	distal	4	no	16.494	16.562	PhosphoSitePlus	ICGC;COSMIC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P19878	NCF2	P28482	MAPK1	S332	A325V	325	Missense	distal	-7	no	14.060	14.044	EPSD	ICGC;COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P19878	NCF2	P28482	MAPK1	S406	D412E	412	Missense	distal	6	no	9.989	10.068	EPSD	ICGC;COSMIC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P52945	PDX1	P28482	MAPK1	S66	E69K	69	Missense	distal	3	no	13.590	13.597	PhosphoSitePlus;EPSD	ICGC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P52945	PDX1	P28482	MAPK1	S273	P276T	276	Missense	distal	3	no	9.754	9.816	EPSD	ICGC;COSMIC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P28562	DUSP1	P28482	MAPK1	T141	L147I	147	Missense	distal	6	no	10.564	10.303	EPSD	ICGC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P28562	DUSP1	P28482	MAPK1	T141	P142T	142	Missense	proximal	1	no	10.564	2.065	EPSD	ICGC;COSMIC	8.102	Loss
CMGC_MAPK_ERK1_MAPK1_ST	P28562	DUSP1	P28482	MAPK1	S323	A319E	319	Missense	distal	-4	no	14.078	14.342	PhosphoSitePlus;EPSD	ICGC;COSMIC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P28562	DUSP1	P28482	MAPK1	S323	D330E	330	Missense	distal	7	no	14.078	14.023	PhosphoSitePlus;EPSD	ICGC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P28562	DUSP1	P28482	MAPK1	S359	S352R	352	Missense	distal	-7	no	16.428	16.427	EPSD	ICGC;COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q15648	MED1	P28482	MAPK1	T212	P213A	213	Missense	proximal	1	no	13.734	6.104	EPSD	ICGC;COSMIC	8.102	Loss
CMGC_MAPK_ERK1_MAPK1_ST	Q15648	MED1	P28482	MAPK1	T212	R214K	214	Missense	proximal	2	no	13.734	13.553	EPSD	ICGC;COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q15648	MED1	P28482	MAPK1	S434	L437R	437	Missense	distal	3	no	12.254	12.211	EPSD	ICGC;COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q15648	MED1	P28482	MAPK1	T522	Q519H	519	Missense	distal	-3	no	12.164	12.112	EPSD	ICGC;COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q15648	MED1	P28482	MAPK1	T562	M557V	557	Missense	distal	-5	no	13.604	13.548	EPSD	ICGC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q15648	MED1	P28482	MAPK1	T562	P568L	568	Missense	distal	6	no	13.604	13.198	EPSD	ICGC;COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q15648	MED1	P28482	MAPK1	S675	P676S	676	Missense	proximal	1	no	13.798	4.403	EPSD	ICGC;COSMIC	8.102	Loss
CMGC_MAPK_ERK1_MAPK1_ST	Q15648	MED1	P28482	MAPK1	S675	P676L	676	Missense	proximal	1	no	13.798	4.988	EPSD	ICGC;COSMIC	8.102	Loss
CMGC_MAPK_ERK1_MAPK1_ST	Q15648	MED1	P28482	MAPK1	T747	P749L	749	Missense	proximal	2	no	11.277	11.130	EPSD	ICGC;COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q15648	MED1	P28482	MAPK1	T747	P748R	748	Missense	proximal	1	no	11.277	1.623	EPSD	ICGC	8.102	Loss
CMGC_MAPK_ERK1_MAPK1_ST	Q15648	MED1	P28482	MAPK1	T751	P749L	749	Missense	proximal	-2	no	8.285	6.368	EPSD	ICGC;COSMIC	8.102	Loss
CMGC_MAPK_ERK1_MAPK1_ST	Q15648	MED1	P28482	MAPK1	T751	P748R	748	Missense	distal	-3	no	8.285	8.266	EPSD	ICGC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q15648	MED1	P28482	MAPK1	T805	P801Q	801	Missense	distal	-4	no	14.897	14.704	EPSD	ICGC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q15648	MED1	P28482	MAPK1	T805	I803V	803	Missense	proximal	-2	no	14.897	14.919	EPSD	ICGC;COSMIC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q15648	MED1	P28482	MAPK1	S1045	T1051I	1051	Missense	distal	6	no	10.040	9.583	EPSD	ICGC;COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q15648	MED1	P28482	MAPK1	T1051	T1051I	1051	Missense	central	0	yes	10.652	0.000	EPSD	ICGC;COSMIC	8.102	Loss
CMGC_MAPK_ERK1_MAPK1_ST	Q15648	MED1	P28482	MAPK1	T1057	T1051I	1051	Missense	distal	-6	no	13.270	13.193	EPSD	ICGC;COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q15648	MED1	P28482	MAPK1	T1057	T1064A	1064	Missense	distal	7	no	13.270	13.299	EPSD	ICGC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q15648	MED1	P28482	MAPK1	S1156	L1163P	1163	Missense	distal	7	no	14.765	14.466	EPSD	ICGC;COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q15648	MED1	P28482	MAPK1	S1156	H1161N	1161	Missense	distal	5	no	14.765	14.837	EPSD	ICGC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q15648	MED1	P28482	MAPK1	S1192	S1192F	1192	Missense	central	0	yes	14.426	0.000	EPSD	ICGC;GDSC;CCLE	8.102	Loss
CMGC_MAPK_ERK1_MAPK1_ST	Q15648	MED1	P28482	MAPK1	S1207	P1208Q	1208	Missense	proximal	1	no	13.792	5.298	EPSD	ICGC	8.102	Loss
CMGC_MAPK_ERK1_MAPK1_ST	Q15648	MED1	P28482	MAPK1	T1215	T1215N	1215	Missense	central	0	yes	15.062	0.000	EPSD	ICGC;COSMIC	8.102	Loss
CMGC_MAPK_ERK1_MAPK1_ST	Q15648	MED1	P28482	MAPK1	T1215	P1208Q	1208	Missense	distal	-7	no	15.062	15.065	EPSD	ICGC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q15648	MED1	P28482	MAPK1	S1223	P1224L	1224	Missense	proximal	1	no	13.462	4.653	EPSD	ICGC;COSMIC	8.102	Loss
CMGC_MAPK_ERK1_MAPK1_ST	Q15648	MED1	P28482	MAPK1	S1294	P1301Q	1301	Missense	distal	7	no	14.110	14.240	EPSD	ICGC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q15648	MED1	P28482	MAPK1	S1294	S1294C	1294	Missense	central	0	yes	14.110	0.000	EPSD	ICGC;COSMIC	8.102	Loss
CMGC_MAPK_ERK1_MAPK1_ST	Q15648	MED1	P28482	MAPK1	T1304	S1302P	1302	Missense	proximal	-2	no	5.420	8.254	EPSD	ICGC;COSMIC	8.102	Gain
CMGC_MAPK_ERK1_MAPK1_ST	Q15648	MED1	P28482	MAPK1	S1433	S1433P	1433	Missense	central	0	yes	15.078	0.000	EPSD	ICGC	8.102	Loss
CMGC_MAPK_ERK1_MAPK1_ST	Q15648	MED1	P28482	MAPK1	S1433	S1437R	1437	Missense	distal	4	no	15.078	15.055	EPSD	ICGC;COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q15648	MED1	P28482	MAPK1	T1440	S1433P	1433	Missense	distal	-7	no	12.233	12.237	EPSD	ICGC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q15648	MED1	P28482	MAPK1	T1440	S1437R	1437	Missense	distal	-3	no	12.233	12.390	EPSD	ICGC;COSMIC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q15648	MED1	P28482	MAPK1	T1457	E1464K	1464	Missense	distal	7	no	14.347	14.355	PhosphoSitePlus;EPSD	ICGC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q15648	MED1	P28482	MAPK1	S1532	S1539C	1539	Missense	distal	7	no	9.948	10.607	EPSD	ICGC;COSMIC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q15648	MED1	P28482	MAPK1	S1532	S1525Y	1525	Missense	distal	-7	no	9.948	9.917	EPSD	ICGC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q15648	MED1	P28482	MAPK1	S1536	S1539C	1539	Missense	distal	3	no	15.287	15.391	EPSD	ICGC;COSMIC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q15648	MED1	P28482	MAPK1	S1558	D1555E	1555	Missense	distal	-3	no	8.659	8.607	EPSD	ICGC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q15648	MED1	P28482	MAPK1	S1558	S1561R	1561	Missense	distal	3	no	8.659	8.635	EPSD	ICGC;COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q15648	MED1	P28482	MAPK1	S1561	D1555E	1555	Missense	distal	-6	no	15.612	15.600	EPSD	ICGC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q15648	MED1	P28482	MAPK1	S1561	S1561R	1561	Missense	central	0	yes	15.612	0.000	EPSD	ICGC;COSMIC	8.102	Loss
CMGC_MAPK_ERK1_MAPK1_ST	P19525	EIF2AK2	P28482	MAPK1	T16	F10V	10	Missense	distal	-6	no	12.588	12.612	EPSD	ICGC;COSMIC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P19525	EIF2AK2	P28482	MAPK1	T16	G22E	22	Missense	distal	6	no	12.588	12.699	EPSD	ICGC;COSMIC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P19525	EIF2AK2	P28482	MAPK1	T16	T16A	16	Missense	central	0	yes	12.588	0.000	EPSD	ICGC;COSMIC	8.102	Loss
CMGC_MAPK_ERK1_MAPK1_ST	P19525	EIF2AK2	P28482	MAPK1	T16	V23I	23	Missense	distal	7	no	12.588	12.853	EPSD	ICGC;COSMIC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P19525	EIF2AK2	P28482	MAPK1	T42	H37N	37	Missense	distal	-5	no	8.851	8.752	EPSD	ICGC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P19525	EIF2AK2	P28482	MAPK1	S83	E78D	78	Missense	distal	-5	no	14.665	14.709	EPSD	ICGC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P19525	EIF2AK2	P28482	MAPK1	S456	T451N	451	Missense	distal	-5	no	14.472	14.395	EPSD	ICGC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P19525	EIF2AK2	P28482	MAPK1	S456	Q459K	459	Missense	distal	3	no	14.472	14.401	EPSD	ICGC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P19525	EIF2AK2	P28482	MAPK1	T529	P523T	523	Missense	distal	-6	no	8.525	8.475	EPSD	ICGC;COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P19525	EIF2AK2	P28482	MAPK1	T529	R526Q	526	Missense	distal	-3	no	8.525	8.248	EPSD	ICGC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q92974	ARHGEF2	P28482	MAPK1	S163	R169L	169	Missense	distal	6	no	15.493	15.193	EPSD	ICGC;COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q92974	ARHGEF2	P28482	MAPK1	S932	E935K	935	Missense	distal	3	no	13.424	13.431	EPSD	ICGC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	O94811	TPPP	P28482	MAPK1	T14	D21E	21	Missense	distal	7	no	15.180	15.125	EPSD	ICGC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	O94811	TPPP	P28482	MAPK1	T14	T14K	14	Missense	central	0	yes	15.180	0.000	EPSD	ICGC;COSMIC	8.102	Loss
CMGC_MAPK_ERK1_MAPK1_ST	O94811	TPPP	P28482	MAPK1	S18	D21E	21	Missense	distal	3	no	19.644	19.549	EPSD;PhosphoSitePlus	ICGC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	O94811	TPPP	P28482	MAPK1	S18	T14K	14	Missense	distal	-4	no	19.644	19.947	EPSD;PhosphoSitePlus	ICGC;COSMIC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	O94811	TPPP	P28482	MAPK1	S18	P22L	22	Missense	distal	4	no	19.644	19.524	EPSD;PhosphoSitePlus	ICGC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	O94811	TPPP	P28482	MAPK1	S45	A44T	44	Missense	proximal	-1	no	13.039	13.034	EPSD	ICGC;COSMIC;GDSC;CCLE	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	O94811	TPPP	P28482	MAPK1	S45	A44V	44	Missense	proximal	-1	no	13.039	13.050	EPSD	ICGC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	O94811	TPPP	P28482	MAPK1	S160	V154G	154	Missense	distal	-6	no	12.599	12.643	PhosphoSitePlus;EPSD	ICGC;COSMIC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	O75582	RPS6KA5	P28482	MAPK1	S15	T14N	14	Missense	proximal	-1	no	8.098	8.146	EPSD	ICGC	8.102	Gain
CMGC_MAPK_ERK1_MAPK1_ST	O75582	RPS6KA5	P28482	MAPK1	S15	G9S	9	Missense	distal	-6	no	8.098	8.115	EPSD	ICGC;COSMIC	8.102	Gain
CMGC_MAPK_ERK1_MAPK1_ST	O75582	RPS6KA5	P28482	MAPK1	S628	L629F	629	Missense	proximal	1	no	6.479	8.719	EPSD	ICGC;COSMIC	8.102	Gain
CMGC_MAPK_ERK1_MAPK1_ST	O75582	RPS6KA5	P28482	MAPK1	T700	P697H	697	Missense	distal	-3	no	14.834	14.485	EPSD	ICGC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	O75582	RPS6KA5	P28482	MAPK1	T775	T774N	774	Missense	proximal	-1	no	15.058	15.106	EPSD	ICGC;COSMIC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P29590	PML	P28482	MAPK1	S387	S388Y	388	Missense	proximal	1	no	5.959	8.345	EPSD	ICGC;COSMIC	8.102	Gain
CMGC_MAPK_ERK1_MAPK1_ST	P29590	PML	P28482	MAPK1	S387	S388F	388	Missense	proximal	1	no	5.959	8.784	EPSD	ICGC;COSMIC	8.102	Gain
CMGC_MAPK_ERK1_MAPK1_ST	P29590	PML	P28482	MAPK1	S403	P410A	410	Missense	distal	7	no	12.980	13.172	EPSD	ICGC;COSMIC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P29590	PML	P28482	MAPK1	S403	V398L	398	Missense	distal	-5	no	12.980	13.033	EPSD	ICGC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P29590	PML	P28482	MAPK1	S403	A407S	407	Missense	distal	4	no	12.980	13.073	EPSD	ICGC;COSMIC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P29590	PML	P28482	MAPK1	S403	A407T	407	Missense	distal	4	no	12.980	12.960	EPSD	ICGC;COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P29590	PML	P28482	MAPK1	T409	P410A	410	Missense	proximal	1	no	13.534	5.904	EPSD	ICGC;COSMIC	8.102	Loss
CMGC_MAPK_ERK1_MAPK1_ST	P29590	PML	P28482	MAPK1	T409	A407S	407	Missense	proximal	-2	no	13.534	13.847	EPSD	ICGC;COSMIC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P29590	PML	P28482	MAPK1	T409	A407T	407	Missense	proximal	-2	no	13.534	13.982	EPSD	ICGC;COSMIC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P29590	PML	P28482	MAPK1	S504	S505F	505	Missense	proximal	1	no	6.422	9.248	EPSD	ICGC	8.102	Gain
CMGC_MAPK_ERK1_MAPK1_ST	P29590	PML	P28482	MAPK1	S505	Q508H	508	Missense	distal	3	no	13.675	13.696	EPSD	ICGC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P29590	PML	P28482	MAPK1	S505	S505F	505	Missense	central	0	yes	13.675	0.000	EPSD	ICGC	8.102	Loss
CMGC_MAPK_ERK1_MAPK1_ST	P29590	PML	P28482	MAPK1	S518	P525L	525	Missense	distal	7	no	14.880	15.179	EPSD	ICGC;COSMIC;GDSC;CCLE	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P29590	PML	P28482	MAPK1	S527	P525L	525	Missense	proximal	-2	no	15.991	14.074	EPSD;PhosphoSitePlus	ICGC;COSMIC;GDSC;CCLE	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P29590	PML	P28482	MAPK1	S527	P526L	526	Missense	proximal	-1	no	15.991	15.931	EPSD;PhosphoSitePlus	ICGC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P29590	PML	P28482	MAPK1	S530	P525L	525	Missense	distal	-5	no	16.722	16.871	EPSD;PhosphoSitePlus	ICGC;COSMIC;GDSC;CCLE	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P29590	PML	P28482	MAPK1	S530	S535L	535	Missense	distal	5	no	16.722	16.491	EPSD;PhosphoSitePlus	ICGC;COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P29590	PML	P28482	MAPK1	S530	P526L	526	Missense	distal	-4	no	16.722	16.418	EPSD;PhosphoSitePlus	ICGC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P29590	PML	P28482	MAPK1	S570	S571F	571	Missense	proximal	1	no	5.475	8.301	EPSD	ICGC	8.102	Gain
CMGC_MAPK_ERK1_MAPK1_ST	P29590	PML	P28482	MAPK1	T592	L593P	593	Missense	proximal	1	no	8.676	17.486	EPSD	ICGC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P29590	PML	P28482	MAPK1	T592	Q586H	586	Missense	distal	-6	no	8.676	8.617	EPSD	ICGC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P29590	PML	P28482	MAPK1	T592	S591C	591	Missense	proximal	-1	no	8.676	8.598	EPSD	ICGC;COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P29590	PML	P28482	MAPK1	T592	L596F	596	Missense	distal	4	no	8.676	8.609	EPSD	ICGC;COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P29590	PML	P28482	MAPK1	T867	R861W	861	Missense	distal	-6	no	17.434	17.214	EPSD	ICGC;COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P29590	PML	P28482	MAPK1	T867	P868T	868	Missense	proximal	1	no	17.434	8.935	EPSD	ICGC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P29590	PML	P28482	MAPK1	T867	P868S	868	Missense	proximal	1	no	17.434	8.039	EPSD	ICGC	8.102	Loss
CMGC_MAPK_ERK1_MAPK1_ST	P29590	PML	P28482	MAPK1	T867	G873C	873	Missense	distal	6	no	17.434	16.644	EPSD	ICGC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P29590	PML	P28482	MAPK1	S879	A875E	875	Missense	distal	-4	no	8.027	8.291	EPSD	ICGC	8.102	Gain
CMGC_MAPK_ERK1_MAPK1_ST	Q15700	DLG2	P28482	MAPK1	S328	P329S	329	Missense	proximal	1	no	13.340	3.945	EPSD	ICGC;COSMIC	8.102	Loss
CMGC_MAPK_ERK1_MAPK1_ST	Q9NRA0	SPHK2	P28482	MAPK1	S472	S473T	473	Missense	proximal	1	no	7.257	8.153	EPSD	ICGC	8.102	Gain
CMGC_MAPK_ERK1_MAPK1_ST	Q9NRA0	SPHK2	P28482	MAPK1	S477	S473T	473	Missense	distal	-4	no	16.777	16.547	EPSD	ICGC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q9NRA0	SPHK2	P28482	MAPK1	T614	P612Q	612	Missense	proximal	-2	no	15.533	12.539	EPSD;PhosphoSitePlus	ICGC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P35236	PTPN7	P28482	MAPK1	S93	Q88R	88	Missense	distal	-5	no	17.799	17.721	EPSD;PhosphoSitePlus	ICGC;COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P05412	JUN	P28482	MAPK1	S21	L14F	14	Missense	distal	-7	no	8.115	8.103	EPSD	ICGC;COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P05412	JUN	P28482	MAPK1	S21	N15K	15	Missense	distal	-6	no	8.115	8.123	EPSD	ICGC;COSMIC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P05412	JUN	P28482	MAPK1	S63	K70T	70	Missense	distal	7	no	13.422	13.625	EPSD;PhosphoSitePlus	ICGC;COSMIC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P05412	JUN	P28482	MAPK1	S73	A72E	72	Missense	proximal	-1	no	14.757	14.779	PhosphoSitePlus;EPSD	ICGC;COSMIC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P05412	JUN	P28482	MAPK1	S73	K70T	70	Missense	distal	-3	no	14.757	14.805	PhosphoSitePlus;EPSD	ICGC;COSMIC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P05412	JUN	P28482	MAPK1	T91	T93N	93	Missense	proximal	2	no	13.961	13.936	EPSD	ICGC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P05412	JUN	P28482	MAPK1	T91	L98R	98	Missense	distal	7	no	13.961	13.676	EPSD	ICGC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P05412	JUN	P28482	MAPK1	T93	T93N	93	Missense	central	0	yes	11.641	0.000	EPSD	ICGC	8.102	Loss
CMGC_MAPK_ERK1_MAPK1_ST	P05412	JUN	P28482	MAPK1	T93	L98R	98	Missense	distal	5	no	11.641	11.904	EPSD	ICGC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P05412	JUN	P28482	MAPK1	T239	T239K	239	Missense	central	0	yes	14.415	0.000	EPSD	ICGC	8.102	Loss
CMGC_MAPK_ERK1_MAPK1_ST	P05412	JUN	P28482	MAPK1	S243	T239K	239	Missense	distal	-4	no	15.977	16.280	EPSD	ICGC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P05412	JUN	P28482	MAPK1	T330	Q327L	327	Missense	distal	-3	no	9.565	9.478	EPSD	ICGC;COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P05412	JUN	P28482	MAPK1	T330	T330K	330	Missense	central	0	yes	9.565	0.000	EPSD	ICGC	8.102	Loss
CMGC_MAPK_ERK1_MAPK1_ST	P05412	JUN	P28482	MAPK1	T330	M323I	323	Missense	distal	-7	no	9.565	9.554	EPSD	ICGC;COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q02750	MAP2K1	P28482	MAPK1	S18	A14S	14	Missense	distal	-4	no	8.439	8.649	EPSD	ICGC;COSMIC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q02750	MAP2K1	P28482	MAPK1	S18	G17V	17	Missense	proximal	-1	no	8.439	8.468	EPSD	ICGC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q02750	MAP2K1	P28482	MAPK1	S231	P232R	232	Missense	proximal	1	no	16.182	6.528	EPSD	ICGC	8.102	Loss
CMGC_MAPK_ERK1_MAPK1_ST	Q02750	MAP2K1	P28482	MAPK1	S231	R234I	234	Missense	distal	3	no	16.182	16.264	EPSD	ICGC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q02750	MAP2K1	P28482	MAPK1	S231	G225C	225	Missense	distal	-6	no	16.182	16.059	EPSD	ICGC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q02750	MAP2K1	P28482	MAPK1	T286	P288H	288	Missense	proximal	2	no	12.915	12.785	PhosphoSitePlus;EPSD	ICGC;COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q02750	MAP2K1	P28482	MAPK1	T292	P288H	288	Missense	distal	-4	no	18.747	18.506	EPSD;PhosphoSitePlus	ICGC;COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q02750	MAP2K1	P28482	MAPK1	T292	G294W	294	Missense	proximal	2	no	18.747	18.474	EPSD;PhosphoSitePlus	ICGC;COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q02750	MAP2K1	P28482	MAPK1	T292	P296H	296	Missense	distal	4	no	18.747	18.572	EPSD;PhosphoSitePlus	ICGC;COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q02750	MAP2K1	P28482	MAPK1	S299	G294W	294	Missense	distal	-5	no	9.200	9.456	EPSD	ICGC;COSMIC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q02750	MAP2K1	P28482	MAPK1	S299	P296H	296	Missense	distal	-3	no	9.200	8.851	EPSD	ICGC;COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q02750	MAP2K1	P28482	MAPK1	T386	S385G	385	Missense	proximal	-1	no	18.316	18.305	EPSD;PhosphoSitePlus	ICGC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P32004	L1CAM	P28482	MAPK1	S163	P157L	157	Missense	distal	-6	no	10.716	10.624	EPSD	ICGC;COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q16665	HIF1A	P28482	MAPK1	S15	K10N	10	Missense	distal	-5	no	9.164	9.187	EPSD	ICGC;COSMIC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q16665	HIF1A	P28482	MAPK1	S15	R18Q	18	Missense	distal	3	no	9.164	9.186	EPSD	ICGC;COSMIC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q16665	HIF1A	P28482	MAPK1	S15	R17G	17	Missense	proximal	2	no	9.164	9.069	EPSD	ICGC;COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q16665	HIF1A	P28482	MAPK1	S15	K19Q	19	Missense	distal	4	no	9.164	9.079	EPSD	ICGC;COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q08499	PDE4D	P28482	MAPK1	S14	G15A	15	Missense	proximal	1	no	8.133	10.568	EPSD	ICGC;COSMIC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q08499	PDE4D	P28482	MAPK1	S14	A8V	8	Missense	distal	-6	no	8.133	8.086	EPSD	ICGC;COSMIC	8.102	Loss
CMGC_MAPK_ERK1_MAPK1_ST	Q08499	PDE4D	P28482	MAPK1	S14	A12V	12	Missense	proximal	-2	no	8.133	9.407	EPSD	ICGC;COSMIC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q08499	PDE4D	P28482	MAPK1	S18	G15A	15	Missense	distal	-3	no	9.011	8.832	EPSD	ICGC;COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q08499	PDE4D	P28482	MAPK1	S18	A12V	12	Missense	distal	-6	no	9.011	8.964	EPSD	ICGC;COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q08499	PDE4D	P28482	MAPK1	S18	A24V	24	Missense	distal	6	no	9.011	9.092	EPSD	ICGC;COSMIC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q08499	PDE4D	P28482	MAPK1	S171	I177V	177	Missense	distal	6	no	13.993	14.446	EPSD	ICGC;COSMIC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q08499	PDE4D	P28482	MAPK1	S202	D196E	196	Missense	distal	-6	no	12.862	12.850	EPSD	ICGC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q08499	PDE4D	P28482	MAPK1	S202	N209S	209	Missense	distal	7	no	12.862	12.879	EPSD	ICGC;COSMIC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q08499	PDE4D	P28482	MAPK1	S202	Y199C	199	Missense	distal	-3	no	12.862	12.605	EPSD	ICGC;GDSC;CCLE	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q08499	PDE4D	P28482	MAPK1	T224	D220E	220	Missense	distal	-4	no	16.153	16.138	EPSD	ICGC;COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q08499	PDE4D	P28482	MAPK1	T224	H217N	217	Missense	distal	-7	no	16.153	16.167	EPSD	ICGC;COSMIC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q08499	PDE4D	P28482	MAPK1	S255	Q260K	260	Missense	distal	5	no	14.149	14.183	EPSD	ICGC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q08499	PDE4D	P28482	MAPK1	S255	S252R	252	Missense	distal	-3	no	14.149	14.305	EPSD	ICGC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q08499	PDE4D	P28482	MAPK1	S255	P251H	251	Missense	distal	-4	no	14.149	13.907	EPSD	ICGC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q08499	PDE4D	P28482	MAPK1	S362	Q363E	363	Missense	proximal	1	no	10.937	10.660	EPSD	ICGC;COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q08499	PDE4D	P28482	MAPK1	S362	P360Q	360	Missense	proximal	-2	no	10.937	7.944	EPSD	ICGC;COSMIC	8.102	Loss
CMGC_MAPK_ERK1_MAPK1_ST	Q08499	PDE4D	P28482	MAPK1	S657	R652H	652	Missense	distal	-5	no	12.270	12.348	EPSD	ICGC;COSMIC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q08499	PDE4D	P28482	MAPK1	S657	M654V	654	Missense	distal	-3	no	12.270	12.401	EPSD	ICGC;COSMIC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q08499	PDE4D	P28482	MAPK1	S657	H663N	663	Missense	distal	6	no	12.270	12.480	EPSD	ICGC;COSMIC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q08499	PDE4D	P28482	MAPK1	S715	S715N	715	Missense	central	0	yes	17.970	0.000	EPSD	ICGC	8.102	Loss
CMGC_MAPK_ERK1_MAPK1_ST	Q08499	PDE4D	P28482	MAPK1	S717	S715N	715	Missense	proximal	-2	no	12.429	12.443	EPSD	ICGC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q08499	PDE4D	P28482	MAPK1	S717	P723Q	723	Missense	distal	6	no	12.429	12.142	EPSD	ICGC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q3V6T2	CCDC88A	P28482	MAPK1	S16	S16R	16	Missense	central	0	yes	13.968	0.000	EPSD	ICGC;COSMIC	8.102	Loss
CMGC_MAPK_ERK1_MAPK1_ST	Q3V6T2	CCDC88A	P28482	MAPK1	S16	Q12K	12	Missense	distal	-4	no	13.968	14.150	EPSD	ICGC;COSMIC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q3V6T2	CCDC88A	P28482	MAPK1	S1387	P1388S	1388	Missense	proximal	1	no	11.870	2.475	EPSD	ICGC;COSMIC	8.102	Loss
CMGC_MAPK_ERK1_MAPK1_ST	Q9ULV5	HSF4	P28482	MAPK1	S40	S45C	45	Missense	distal	5	no	15.426	15.026	EPSD	ICGC;COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q9ULV5	HSF4	P28482	MAPK1	S40	L36P	36	Missense	distal	-4	no	15.426	15.730	EPSD	ICGC;COSMIC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q9ULV5	HSF4	P28482	MAPK1	S298	G301V	301	Missense	distal	3	no	16.871	16.845	PhosphoSitePlus	ICGC;COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q9ULV5	HSF4	P28482	MAPK1	S489	G485V	485	Missense	distal	-4	no	16.283	16.279	EPSD	ICGC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q9ULV5	HSF4	P28482	MAPK1	S491	G485V	485	Missense	distal	-6	no	16.331	16.287	EPSD	ICGC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q9Y463	DYRK1B	P28482	MAPK1	S554	P559L	559	Missense	distal	5	no	17.752	17.539	EPSD	ICGC;COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q9Y463	DYRK1B	P28482	MAPK1	S557	P559L	559	Missense	proximal	2	no	16.760	16.612	EPSD	ICGC;COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q8N122	RPTOR	P28482	MAPK1	S8	M5I	5	Missense	distal	-3	no	13.924	13.920	EPSD;PhosphoSitePlus	ICGC;COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q8N122	RPTOR	P28482	MAPK1	S8	G12V	12	Missense	distal	4	no	13.924	13.874	EPSD;PhosphoSitePlus	ICGC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q8N122	RPTOR	P28482	MAPK1	S8	G14R	14	Missense	distal	6	no	13.924	13.894	EPSD;PhosphoSitePlus	ICGC;COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q8N122	RPTOR	P28482	MAPK1	S696	T699M	699	Missense	distal	3	no	14.063	14.086	PhosphoSitePlus;EPSD	ICGC;COSMIC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q8N122	RPTOR	P28482	MAPK1	T699	T699M	699	Missense	central	0	yes	8.654	0.000	EPSD	ICGC;COSMIC	8.102	Loss
CMGC_MAPK_ERK1_MAPK1_ST	Q8N122	RPTOR	P28482	MAPK1	T706	T699M	699	Missense	distal	-7	no	13.957	13.952	EPSD	ICGC;COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q8N122	RPTOR	P28482	MAPK1	S881	S887N	887	Missense	distal	6	no	8.691	8.595	EPSD	ICGC;COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q8N122	RPTOR	P28482	MAPK1	T908	A914V	914	Missense	distal	6	no	8.227	8.308	EPSD	ICGC;COSMIC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q8N122	RPTOR	P28482	MAPK1	T917	A914V	914	Missense	distal	-3	no	11.419	11.479	EPSD	ICGC;COSMIC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q8N122	RPTOR	P28482	MAPK1	S920	A914V	914	Missense	distal	-6	no	8.381	8.334	EPSD	ICGC;COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P49407	ARRB1	P28482	MAPK1	T275	Y272C	272	Missense	distal	-3	no	11.183	10.925	EPSD	ICGC;COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P49407	ARRB1	P28482	MAPK1	T275	A279D	279	Missense	distal	4	no	11.183	11.179	EPSD	ICGC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P49407	ARRB1	P28482	MAPK1	T275	P276L	276	Missense	proximal	1	no	11.183	2.373	EPSD	ICGC	8.102	Loss
CMGC_MAPK_ERK1_MAPK1_ST	P49407	ARRB1	P28482	MAPK1	S412	Q414H	414	Missense	proximal	2	no	17.031	17.080	PhosphoSitePlus	ICGC;COSMIC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q53EZ4	CEP55	P28482	MAPK1	S243	A244P	244	Missense	proximal	1	no	6.352	13.982	EPSD	ICGC;COSMIC	8.102	Gain
CMGC_MAPK_ERK1_MAPK1_ST	Q53EZ4	CEP55	P28482	MAPK1	S396	L397F	397	Missense	proximal	1	no	6.103	8.343	EPSD	ICGC;COSMIC	8.102	Gain
CMGC_MAPK_ERK1_MAPK1_ST	Q53EZ4	CEP55	P28482	MAPK1	S425	S428I	428	Missense	distal	3	no	14.555	14.614	PhosphoSitePlus;EPSD	ICGC;COSMIC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q53EZ4	CEP55	P28482	MAPK1	S428	S428I	428	Missense	central	0	yes	16.148	0.000	EPSD;PhosphoSitePlus	ICGC;COSMIC	8.102	Loss
CMGC_MAPK_ERK1_MAPK1_ST	P31645	SLC6A4	P28482	MAPK1	S52	S52R	52	Missense	central	0	yes	16.017	0.000	EPSD	ICGC;COSMIC	8.102	Loss
CMGC_MAPK_ERK1_MAPK1_ST	P31645	SLC6A4	P28482	MAPK1	S559	S559R	559	Missense	central	0	yes	16.774	0.000	EPSD	ICGC	8.102	Loss
CMGC_MAPK_ERK1_MAPK1_ST	P31645	SLC6A4	P28482	MAPK1	S559	P561L	561	Missense	proximal	2	no	16.774	16.627	EPSD	ICGC;COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P31645	SLC6A4	P28482	MAPK1	S559	S555I	555	Missense	distal	-4	no	16.774	16.187	EPSD	ICGC;GDSC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P31645	SLC6A4	P28482	MAPK1	S559	P561S	561	Missense	proximal	2	no	16.774	16.747	EPSD	ICGC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P31645	SLC6A4	P28482	MAPK1	T603	K605N	605	Missense	proximal	2	no	10.040	10.031	EPSD	ICGC;COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P31645	SLC6A4	P28482	MAPK1	T603	G602E	602	Missense	proximal	-1	no	10.040	10.079	EPSD	ICGC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P31645	SLC6A4	P28482	MAPK1	T613	P617Q	617	Missense	distal	4	no	15.011	14.902	EPSD	ICGC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P31645	SLC6A4	P28482	MAPK1	T616	P617Q	617	Missense	proximal	1	no	18.535	10.042	PhosphoSitePlus	ICGC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P33076	CIITA	P28482	MAPK1	T740	P741S	741	Missense	proximal	1	no	14.428	5.033	EPSD	ICGC;COSMIC	8.102	Loss
CMGC_MAPK_ERK1_MAPK1_ST	P33076	CIITA	P28482	MAPK1	T740	A738T	738	Missense	proximal	-2	no	14.428	14.875	EPSD	ICGC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P33076	CIITA	P28482	MAPK1	S834	R839H	839	Missense	distal	5	no	8.103	7.926	EPSD	ICGC;COSMIC	8.102	Loss
CMGC_MAPK_ERK1_MAPK1_ST	P33076	CIITA	P28482	MAPK1	S834	R839C	839	Missense	distal	5	no	8.103	7.671	EPSD	ICGC;COSMIC	8.102	Loss
CMGC_MAPK_ERK1_MAPK1_ST	P33076	CIITA	P28482	MAPK1	S834	G831V	831	Missense	distal	-3	no	8.103	7.984	EPSD	ICGC	8.102	Loss
CMGC_MAPK_ERK1_MAPK1_ST	P78347	GTF2I	P28482	MAPK1	T24	S17L	17	Missense	distal	-7	no	9.420	9.412	EPSD	ICGC;COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P78347	GTF2I	P28482	MAPK1	S210	A204T	204	Missense	distal	-6	no	15.139	15.129	EPSD	ICGC;COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P78347	GTF2I	P28482	MAPK1	S210	C215S	215	Missense	distal	5	no	15.139	15.539	EPSD	ICGC;COSMIC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P78347	GTF2I	P28482	MAPK1	S210	A204S	204	Missense	distal	-6	no	15.139	15.152	EPSD	ICGC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P78347	GTF2I	P28482	MAPK1	T413	R409C	409	Missense	distal	-4	no	10.176	9.538	EPSD	ICGC;COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q14790	CASP8	P28482	MAPK1	S16	D18Y	18	Missense	proximal	2	no	8.781	8.602	EPSD	ICGC;COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q14790	CASP8	P28482	MAPK1	S16	I10T	10	Missense	distal	-6	no	8.781	8.859	EPSD	ICGC;COSMIC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q14790	CASP8	P28482	MAPK1	S16	G11E	11	Missense	distal	-5	no	8.781	8.739	EPSD	ICGC;COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q14790	CASP8	P28482	MAPK1	S16	L22I	22	Missense	distal	6	no	8.781	8.521	EPSD	ICGC;COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q14790	CASP8	P28482	MAPK1	S16	G11R	11	Missense	distal	-5	no	8.781	8.761	EPSD	ICGC;COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q14790	CASP8	P28482	MAPK1	S16	L22F	22	Missense	distal	6	no	8.781	8.747	EPSD	ICGC;COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q14790	CASP8	P28482	MAPK1	S16	D18V	18	Missense	proximal	2	no	8.781	8.744	EPSD	ICGC;COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q14790	CASP8	P28482	MAPK1	S21	L22F	22	Missense	proximal	1	no	7.025	9.265	EPSD	ICGC;COSMIC	8.102	Gain
CMGC_MAPK_ERK1_MAPK1_ST	Q14790	CASP8	P28482	MAPK1	S60	L62P	62	Missense	proximal	2	no	8.126	8.273	EPSD	ICGC;COSMIC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q14790	CASP8	P28482	MAPK1	S60	S57C	57	Missense	distal	-3	no	8.126	7.599	EPSD	ICGC;COSMIC	8.102	Loss
CMGC_MAPK_ERK1_MAPK1_ST	Q14790	CASP8	P28482	MAPK1	S60	F67L	67	Missense	distal	7	no	8.126	8.067	EPSD	ICGC;COSMIC	8.102	Loss
CMGC_MAPK_ERK1_MAPK1_ST	Q14790	CASP8	P28482	MAPK1	S60	N58S	58	Missense	proximal	-2	no	8.126	8.111	EPSD	ICGC;COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q14790	CASP8	P28482	MAPK1	S60	S60P	60	Missense	central	0	yes	8.126	0.000	EPSD	ICGC;COSMIC	8.102	Loss
CMGC_MAPK_ERK1_MAPK1_ST	Q14790	CASP8	P28482	MAPK1	S60	E64V	64	Missense	distal	4	no	8.126	8.053	EPSD	ICGC;COSMIC	8.102	Loss
CMGC_MAPK_ERK1_MAPK1_ST	P28482	MAPK1	P28482	MAPK1	S29	L28I	28	Missense	proximal	-1	no	8.276	8.270	EPSD	ICGC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P28482	MAPK1	P28482	MAPK1	S29	R24C	24	Missense	distal	-5	no	8.276	8.506	EPSD	ICGC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P28482	MAPK1	P28482	MAPK1	S142	D149Y	149	Missense	distal	7	no	8.024	8.545	EPSD	ICGC	8.102	Gain
CMGC_MAPK_ERK1_MAPK1_ST	P28482	MAPK1	P28482	MAPK1	T185	T181K	181	Missense	distal	-4	no	8.330	8.633	EPSD	ICGC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P28482	MAPK1	P28482	MAPK1	T185	T185K	185	Missense	central	0	yes	8.330	0.000	EPSD	ICGC	8.102	Loss
CMGC_MAPK_ERK1_MAPK1_ST	P28482	MAPK1	P28482	MAPK1	T185	W192L	192	Missense	distal	7	no	8.330	7.644	EPSD	ICGC;COSMIC	8.102	Loss
CMGC_MAPK_ERK1_MAPK1_ST	O43521	BCL2L11	P28482	MAPK1	S59	G62S	62	Missense	distal	3	no	13.276	13.261	EPSD	ICGC;COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	O43521	BCL2L11	P28482	MAPK1	S59	P56L	56	Missense	distal	-3	no	13.276	12.892	EPSD	ICGC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	O43521	BCL2L11	P28482	MAPK1	S59	G52W	52	Missense	distal	-7	no	13.276	13.238	EPSD	ICGC;COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	O43521	BCL2L11	P28482	MAPK1	S69	G62S	62	Missense	distal	-7	no	15.383	15.397	PhosphoSitePlus	ICGC;COSMIC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	O43521	BCL2L11	P28482	MAPK1	S77	R84G	84	Missense	distal	7	no	14.223	14.288	EPSD	ICGC;COSMIC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	O43521	BCL2L11	P28482	MAPK1	S98	G95W	95	Missense	distal	-3	no	8.256	7.727	EPSD	ICGC;COSMIC	8.102	Loss
CMGC_MAPK_ERK1_MAPK1_ST	O43521	BCL2L11	P28482	MAPK1	S98	S92Y	92	Missense	distal	-6	no	8.256	8.142	EPSD	ICGC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	O43521	BCL2L11	P28482	MAPK1	T116	K112T	112	Missense	distal	-4	no	15.649	15.346	EPSD	ICGC;COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	O43521	BCL2L11	P28482	MAPK1	T116	A123T	123	Missense	distal	7	no	15.649	15.620	EPSD	ICGC;COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	O43521	BCL2L11	P28482	MAPK1	S118	K112T	112	Missense	distal	-6	no	14.907	14.873	EPSD	ICGC;COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	O43521	BCL2L11	P28482	MAPK1	S118	A123T	123	Missense	distal	5	no	14.907	14.993	EPSD	ICGC;COSMIC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	O43521	BCL2L11	P28482	MAPK1	S129	A123T	123	Missense	distal	-6	no	9.362	9.351	EPSD	ICGC;COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P35398	RORA	P28482	MAPK1	S49	S51R	51	Missense	proximal	2	no	10.233	10.374	EPSD	ICGC;COSMIC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P35398	RORA	P28482	MAPK1	S49	S51N	51	Missense	proximal	2	no	10.233	10.184	EPSD	ICGC;COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q9ULC4	MCTS1	P28482	MAPK1	S118	I111M	111	Missense	distal	-7	no	13.945	13.955	EPSD	ICGC;COSMIC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q9ULC4	MCTS1	P28482	MAPK1	S118	P114L	114	Missense	distal	-4	no	13.945	13.640	EPSD	ICGC;COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q9ULC4	MCTS1	P28482	MAPK1	S118	P125L	125	Missense	distal	7	no	13.945	14.244	EPSD	ICGC;COSMIC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P42229	STAT5A	P28482	MAPK1	S128	P129T	129	Missense	proximal	1	no	13.396	4.898	EPSD	ICGC;COSMIC	8.102	Loss
CMGC_MAPK_ERK1_MAPK1_ST	P42229	STAT5A	P28482	MAPK1	S780	D773Y	773	Missense	distal	-7	no	19.102	19.070	PhosphoSitePlus	ICGC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P42229	STAT5A	P28482	MAPK1	S788	R790I	790	Missense	proximal	2	no	9.207	8.923	EPSD	ICGC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q15366	PCBP2	P28482	MAPK1	S188	A194S	194	Missense	distal	6	no	8.253	8.549	EPSD	ICGC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q15366	PCBP2	P28482	MAPK1	S189	A194S	194	Missense	distal	5	no	13.186	13.345	EPSD;PhosphoSitePlus	ICGC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q15366	PCBP2	P28482	MAPK1	T213	L218H	218	Missense	distal	5	no	12.889	12.976	EPSD;PhosphoSitePlus	ICGC;COSMIC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q8N9N5	BANP	P28482	MAPK1	S19	D17H	17	Missense	proximal	-2	no	16.260	16.807	EPSD	ICGC;COSMIC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	O00429	DNM1L	P28482	MAPK1	S126	K123N	123	Missense	distal	-3	no	15.951	16.047	EPSD	ICGC;COSMIC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	O00429	DNM1L	P28482	MAPK1	S526	R530I	530	Missense	distal	4	no	8.336	8.192	EPSD	ICGC;COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	O00429	DNM1L	P28482	MAPK1	S548	A541S	541	Missense	distal	-7	no	14.142	14.141	EPSD	ICGC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	O00429	DNM1L	P28482	MAPK1	S548	S548F	548	Missense	central	0	yes	14.142	0.000	EPSD	ICGC;COSMIC	8.102	Loss
CMGC_MAPK_ERK1_MAPK1_ST	O00429	DNM1L	P28482	MAPK1	S548	A553T	553	Missense	distal	5	no	14.142	14.228	EPSD	ICGC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	O00429	DNM1L	P28482	MAPK1	S548	A553V	553	Missense	distal	5	no	14.142	14.160	EPSD	ICGC;COSMIC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	O00429	DNM1L	P28482	MAPK1	S548	S548Y	548	Missense	central	0	yes	14.142	0.000	EPSD	ICGC;COSMIC	8.102	Loss
CMGC_MAPK_ERK1_MAPK1_ST	Q5T447	HECTD3	P28482	MAPK1	S12	S12F	12	Missense	central	0	yes	16.148	0.000	EPSD	ICGC	8.102	Loss
CMGC_MAPK_ERK1_MAPK1_ST	Q5T447	HECTD3	P28482	MAPK1	T157	L161I	161	Missense	distal	4	no	15.947	15.891	PhosphoSitePlus	ICGC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q5T447	HECTD3	P28482	MAPK1	T157	P158R	158	Missense	proximal	1	no	15.947	6.293	PhosphoSitePlus	ICGC;COSMIC	8.102	Loss
CMGC_MAPK_ERK1_MAPK1_ST	Q5T447	HECTD3	P28482	MAPK1	T157	H160P	160	Missense	distal	3	no	15.947	15.859	PhosphoSitePlus	ICGC;COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q5T447	HECTD3	P28482	MAPK1	S389	R395C	395	Missense	distal	6	no	8.200	7.440	EPSD	ICGC;COSMIC	8.102	Loss
CMGC_MAPK_ERK1_MAPK1_ST	P00533	EGFR	P28482	MAPK1	S511	V505L	505	Missense	distal	-6	no	13.698	13.692	EPSD	ICGC;COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P00533	EGFR	P28482	MAPK1	S511	C510R	510	Missense	proximal	-1	no	13.698	13.800	EPSD	ICGC;COSMIC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P00533	EGFR	P28482	MAPK1	T693	A698T	698	Missense	distal	5	no	16.959	17.045	PhosphoSitePlus	ICGC;COSMIC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P00533	EGFR	P28482	MAPK1	S991	R986Q	986	Missense	distal	-5	no	14.909	14.986	EPSD	ICGC;COSMIC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P00533	EGFR	P28482	MAPK1	S991	S991R	991	Missense	central	0	yes	14.909	0.000	EPSD	ICGC;COSMIC	8.102	Loss
CMGC_MAPK_ERK1_MAPK1_ST	P00533	EGFR	P28482	MAPK1	S991	L989I	989	Missense	proximal	-2	no	14.909	14.932	EPSD	ICGC;COSMIC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P00533	EGFR	P28482	MAPK1	S1130	P1136H	1136	Missense	distal	6	no	8.862	8.557	EPSD	ICGC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P00533	EGFR	P28482	MAPK1	T1150	H1156N	1156	Missense	distal	6	no	7.986	8.195	EPSD	ICGC;COSMIC	8.102	Gain
CMGC_MAPK_ERK1_MAPK1_ST	P00533	EGFR	P28482	MAPK1	S1153	A1155T	1155	Missense	proximal	2	no	14.713	14.792	EPSD	ICGC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P00533	EGFR	P28482	MAPK1	S1153	H1156N	1156	Missense	distal	3	no	14.713	14.616	EPSD	ICGC;COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P00533	EGFR	P28482	MAPK1	S1153	S1153I	1153	Missense	central	0	yes	14.713	0.000	EPSD	ICGC;COSMIC	8.102	Loss
CMGC_MAPK_ERK1_MAPK1_ST	P00533	EGFR	P28482	MAPK1	S1153	F1151I	1151	Missense	proximal	-2	no	14.713	15.460	EPSD	ICGC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P00533	EGFR	P28482	MAPK1	S1153	S1153N	1153	Missense	central	0	yes	14.713	0.000	EPSD	ICGC;COSMIC	8.102	Loss
CMGC_MAPK_ERK1_MAPK1_ST	P00533	EGFR	P28482	MAPK1	S1204	Y1197C	1197	Missense	distal	-7	no	9.983	9.981	EPSD	ICGC;COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P00533	EGFR	P28482	MAPK1	S1204	L1198I	1198	Missense	distal	-6	no	9.983	9.947	EPSD	ICGC;COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P00533	EGFR	P28482	MAPK1	S1205	L1198I	1198	Missense	distal	-7	no	8.412	8.392	EPSD	ICGC;COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P14635	CCNB1	P28482	MAPK1	T29	A33S	33	Missense	distal	4	no	8.260	8.353	EPSD	ICGC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P14635	CCNB1	P28482	MAPK1	T29	P31S	31	Missense	proximal	2	no	8.260	8.232	EPSD	ICGC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P14635	CCNB1	P28482	MAPK1	S116	P109L	109	Missense	distal	-7	no	15.847	15.835	EPSD	ICGC;COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P14635	CCNB1	P28482	MAPK1	S116	E118D	118	Missense	proximal	2	no	15.847	15.898	EPSD	ICGC;COSMIC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P14635	CCNB1	P28482	MAPK1	S116	L121F	121	Missense	distal	5	no	15.847	15.881	EPSD	ICGC;COSMIC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P14635	CCNB1	P28482	MAPK1	S126	S128I	128	Missense	proximal	2	no	13.302	13.159	PhosphoSitePlus;EPSD	ICGC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P14635	CCNB1	P28482	MAPK1	S126	A125S	125	Missense	proximal	-1	no	13.302	13.296	PhosphoSitePlus;EPSD	ICGC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P14635	CCNB1	P28482	MAPK1	S126	L121F	121	Missense	distal	-5	no	13.302	13.316	PhosphoSitePlus;EPSD	ICGC;COSMIC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P14635	CCNB1	P28482	MAPK1	S128	S128I	128	Missense	central	0	yes	14.397	0.000	EPSD;PhosphoSitePlus	ICGC	8.102	Loss
CMGC_MAPK_ERK1_MAPK1_ST	P14635	CCNB1	P28482	MAPK1	S128	A125S	125	Missense	distal	-3	no	14.397	14.587	EPSD;PhosphoSitePlus	ICGC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P14635	CCNB1	P28482	MAPK1	S128	L121F	121	Missense	distal	-7	no	14.397	14.385	EPSD;PhosphoSitePlus	ICGC;COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P14635	CCNB1	P28482	MAPK1	T362	P363R	363	Missense	proximal	1	no	11.836	2.182	EPSD	ICGC	8.102	Loss
CMGC_MAPK_ERK1_MAPK1_ST	P14635	CCNB1	P28482	MAPK1	T362	D357Y	357	Missense	distal	-5	no	11.836	11.971	EPSD	ICGC;COSMIC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P14635	CCNB1	P28482	MAPK1	T362	L369M	369	Missense	distal	7	no	11.836	11.907	EPSD	ICGC;COSMIC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q9H9S0	NANOG	P28482	MAPK1	S52	T48M	48	Missense	distal	-4	no	10.829	10.676	PhosphoSitePlus;EPSD	ICGC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q9H9S0	NANOG	P28482	MAPK1	S52	P46S	46	Missense	distal	-6	no	10.829	10.803	PhosphoSitePlus;EPSD	ICGC;COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q9H9S0	NANOG	P28482	MAPK1	S52	P46T	46	Missense	distal	-6	no	10.829	10.779	PhosphoSitePlus;EPSD	ICGC;COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q9H9S0	NANOG	P28482	MAPK1	S52	D59N	59	Missense	distal	7	no	10.829	10.815	PhosphoSitePlus;EPSD	ICGC;COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q9H9S0	NANOG	P28482	MAPK1	S52	P46H	46	Missense	distal	-6	no	10.829	10.754	PhosphoSitePlus;EPSD	ICGC;COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q9H9S0	NANOG	P28482	MAPK1	S65	T70P	70	Missense	distal	5	no	15.041	15.097	EPSD;PhosphoSitePlus	ICGC;COSMIC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q9H9S0	NANOG	P28482	MAPK1	S65	P66H	66	Missense	proximal	1	no	15.041	7.217	EPSD;PhosphoSitePlus	ICGC;COSMIC;CCLE	8.102	Loss
CMGC_MAPK_ERK1_MAPK1_ST	Q9H9S0	NANOG	P28482	MAPK1	S65	D59N	59	Missense	distal	-6	no	15.041	14.995	EPSD;PhosphoSitePlus	ICGC;COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q9H9S0	NANOG	P28482	MAPK1	S69	T70P	70	Missense	proximal	1	no	6.039	14.538	EPSD	ICGC;COSMIC	8.102	Gain
CMGC_MAPK_ERK1_MAPK1_ST	Q9H9S0	NANOG	P28482	MAPK1	S71	T70P	70	Missense	proximal	-1	no	11.627	11.669	EPSD	ICGC;COSMIC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q9H9S0	NANOG	P28482	MAPK1	S71	P66H	66	Missense	distal	-5	no	11.627	11.752	EPSD	ICGC;COSMIC;CCLE	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q9H9S0	NANOG	P28482	MAPK1	S79	K82N	82	Missense	distal	3	no	9.400	9.393	EPSD	ICGC;COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q9H9S0	NANOG	P28482	MAPK1	S79	A80S	80	Missense	proximal	1	no	9.400	7.635	EPSD	ICGC	8.102	Loss
CMGC_MAPK_ERK1_MAPK1_ST	Q9H9S0	NANOG	P28482	MAPK1	S258	E264Q	264	Missense	distal	6	no	17.279	16.958	EPSD	ICGC;COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q9H9S0	NANOG	P28482	MAPK1	T286	D291N	291	Missense	distal	5	no	14.092	13.994	EPSD	ICGC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q9H9S0	NANOG	P28482	MAPK1	T286	T286I	286	Missense	central	0	yes	14.092	0.000	EPSD	ICGC	8.102	Loss
CMGC_MAPK_ERK1_MAPK1_ST	Q9H9S0	NANOG	P28482	MAPK1	T286	R282M	282	Missense	distal	-4	no	14.092	13.716	EPSD	ICGC;COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q8IW41	MAPKAPK5	P28482	MAPK1	S212	Y218C	218	Missense	distal	6	no	14.838	14.589	EPSD	ICGC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q8IW41	MAPKAPK5	P28482	MAPK1	S212	G207V	207	Missense	distal	-5	no	14.838	14.866	EPSD	ICGC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q8IW41	MAPKAPK5	P28482	MAPK1	T214	Y218C	218	Missense	distal	4	no	14.150	14.063	EPSD	ICGC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q8IW41	MAPKAPK5	P28482	MAPK1	T214	G207V	207	Missense	distal	-7	no	14.150	14.149	EPSD	ICGC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q8IW41	MAPKAPK5	P28482	MAPK1	T217	Y218C	218	Missense	proximal	1	no	11.667	5.227	EPSD	ICGC	8.102	Loss
CMGC_MAPK_ERK1_MAPK1_ST	P61978	HNRNPK	P28482	MAPK1	T13	N16S	16	Missense	distal	3	no	9.240	9.318	EPSD	ICGC;COSMIC;CCLE	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P61978	HNRNPK	P28482	MAPK1	S116	T118N	118	Missense	proximal	2	no	16.136	16.110	EPSD	ICGC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P61978	HNRNPK	P28482	MAPK1	S116	E110Q	110	Missense	distal	-6	no	16.136	16.109	EPSD	ICGC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P61978	HNRNPK	P28482	MAPK1	S116	E110D	110	Missense	distal	-6	no	16.136	16.148	EPSD	ICGC;COSMIC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P61978	HNRNPK	P28482	MAPK1	S116	L123H	123	Missense	distal	7	no	16.136	16.070	EPSD	ICGC;COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P61978	HNRNPK	P28482	MAPK1	S188	C185F	185	Missense	distal	-3	no	8.030	8.324	EPSD	ICGC;COSMIC	8.102	Gain
CMGC_MAPK_ERK1_MAPK1_ST	P61978	HNRNPK	P28482	MAPK1	S216	D211H	211	Missense	distal	-5	no	12.959	13.014	EPSD	ICGC;COSMIC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P61978	HNRNPK	P28482	MAPK1	S216	I213M	213	Missense	distal	-3	no	12.959	12.963	EPSD	ICGC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P61978	HNRNPK	P28482	MAPK1	S379	G384D	384	Missense	distal	5	no	10.565	10.609	EPSD	ICGC;COSMIC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P61978	HNRNPK	P28482	MAPK1	S379	G385V	385	Missense	distal	6	no	10.565	10.427	EPSD	ICGC;COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P61978	HNRNPK	P28482	MAPK1	S379	R377S	377	Missense	proximal	-2	no	10.565	9.549	EPSD	ICGC;COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P61978	HNRNPK	P28482	MAPK1	S379	A374E	374	Missense	distal	-5	no	10.565	10.465	EPSD	ICGC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P61978	HNRNPK	P28482	MAPK1	S379	G385R	385	Missense	distal	6	no	10.565	10.535	EPSD	ICGC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P29966	MARCKS	P28482	MAPK1	S27	G33R	33	Missense	distal	6	no	15.041	15.011	EPSD	ICGC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P29966	MARCKS	P28482	MAPK1	S81	E86K	86	Missense	distal	5	no	13.857	13.797	EPSD	ICGC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P29966	MARCKS	P28482	MAPK1	S118	S118L	118	Missense	central	0	yes	16.251	0.000	EPSD	ICGC;COSMIC	8.102	Loss
CMGC_MAPK_ERK1_MAPK1_ST	P29966	MARCKS	P28482	MAPK1	S118	E125G	125	Missense	distal	7	no	16.251	16.379	EPSD	ICGC;COSMIC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P29966	MARCKS	P28482	MAPK1	S135	S132L	132	Missense	distal	-3	no	13.528	13.321	EPSD	ICGC;COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P29966	MARCKS	P28482	MAPK1	S135	S134T	134	Missense	proximal	-1	no	13.528	13.529	EPSD	ICGC;COSMIC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P29966	MARCKS	P28482	MAPK1	T143	P144S	144	Missense	proximal	1	no	11.782	2.387	EPSD	ICGC;COSMIC	8.102	Loss
CMGC_MAPK_ERK1_MAPK1_ST	P29966	MARCKS	P28482	MAPK1	S145	P144S	144	Missense	proximal	-1	no	13.205	13.162	EPSD	ICGC;COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P29966	MARCKS	P28482	MAPK1	T150	P144S	144	Missense	distal	-6	no	12.657	12.631	EPSD	ICGC;COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	O43524	FOXO3	P28482	MAPK1	S7	P10T	10	Missense	distal	3	no	17.200	17.262	EPSD	ICGC;COSMIC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	O43524	FOXO3	P28482	MAPK1	S12	P10T	10	Missense	proximal	-2	no	18.335	15.635	EPSD;PhosphoSitePlus	ICGC;COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	O43524	FOXO3	P28482	MAPK1	S26	S26C	26	Missense	central	0	yes	10.103	0.000	EPSD	ICGC;COSMIC	8.102	Loss
CMGC_MAPK_ERK1_MAPK1_ST	O43524	FOXO3	P28482	MAPK1	S280	A273G	273	Missense	distal	-7	no	9.635	9.619	EPSD	ICGC;COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	O43524	FOXO3	P28482	MAPK1	S280	S286T	286	Missense	distal	6	no	9.635	9.425	EPSD	ICGC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	O43524	FOXO3	P28482	MAPK1	S280	S286F	286	Missense	distal	6	no	9.635	9.194	EPSD	ICGC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	O43524	FOXO3	P28482	MAPK1	S284	S286T	286	Missense	proximal	2	no	15.289	15.266	EPSD	ICGC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	O43524	FOXO3	P28482	MAPK1	S284	S286F	286	Missense	proximal	2	no	15.289	15.157	EPSD	ICGC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	O43524	FOXO3	P28482	MAPK1	S325	S330N	330	Missense	distal	5	no	14.621	14.549	EPSD	ICGC;COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	O43524	FOXO3	P28482	MAPK1	S344	D339N	339	Missense	distal	-5	no	18.067	18.023	EPSD;PhosphoSitePlus	ICGC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	O43524	FOXO3	P28482	MAPK1	S344	D339V	339	Missense	distal	-5	no	18.067	18.093	EPSD;PhosphoSitePlus	ICGC;COSMIC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	O43524	FOXO3	P28482	MAPK1	S402	S399F	399	Missense	distal	-3	no	13.773	13.541	EPSD	ICGC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	O43524	FOXO3	P28482	MAPK1	S425	G424S	424	Missense	proximal	-1	no	14.483	14.494	EPSD;PhosphoSitePlus	ICGC;COSMIC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	O43524	FOXO3	P28482	MAPK1	S425	G420S	420	Missense	distal	-5	no	14.483	14.489	EPSD;PhosphoSitePlus	ICGC;COSMIC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	O43524	FOXO3	P28482	MAPK1	S425	S429Y	429	Missense	distal	4	no	14.483	14.289	EPSD;PhosphoSitePlus	ICGC;COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	O43524	FOXO3	P28482	MAPK1	S428	S429Y	429	Missense	proximal	1	no	5.810	8.196	EPSD	ICGC;COSMIC	8.102	Gain
CMGC_MAPK_ERK1_MAPK1_ST	O43524	FOXO3	P28482	MAPK1	S446	N441K	441	Missense	distal	-5	no	14.355	14.332	EPSD	ICGC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	O43524	FOXO3	P28482	MAPK1	S446	S442F	442	Missense	distal	-4	no	14.355	14.094	EPSD	ICGC;COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	O43524	FOXO3	P28482	MAPK1	S667	S669I	669	Missense	proximal	2	no	10.107	9.964	EPSD	ICGC;COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P24941	CDK2	P28482	MAPK1	T14	V18L	18	Missense	distal	4	no	8.636	8.625	EPSD	ICGC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P24941	CDK2	P28482	MAPK1	T14	A21T	21	Missense	distal	7	no	8.636	8.607	EPSD	ICGC;COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q05209	PTPN12	P28482	MAPK1	S19	P20H	20	Missense	proximal	1	no	15.780	7.956	EPSD	ICGC;COSMIC	8.102	Loss
CMGC_MAPK_ERK1_MAPK1_ST	Q05209	PTPN12	P28482	MAPK1	S19	R13S	13	Missense	distal	-6	no	15.780	15.745	EPSD	ICGC;COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q05209	PTPN12	P28482	MAPK1	T81	Y88F	88	Missense	distal	7	no	13.888	13.718	EPSD	ICGC;COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q05209	PTPN12	P28482	MAPK1	T81	Q84H	84	Missense	distal	3	no	13.888	13.909	EPSD	ICGC;COSMIC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q05209	PTPN12	P28482	MAPK1	T81	D85G	85	Missense	distal	4	no	13.888	13.936	EPSD	ICGC;COSMIC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q05209	PTPN12	P28482	MAPK1	T81	V75A	75	Missense	distal	-6	no	13.888	13.935	EPSD	ICGC;COSMIC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q05209	PTPN12	P28482	MAPK1	T81	R74L	74	Missense	distal	-7	no	13.888	13.881	EPSD	ICGC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q05209	PTPN12	P28482	MAPK1	T569	S567T	567	Missense	proximal	-2	no	11.581	11.716	EPSD	ICGC;COSMIC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q05209	PTPN12	P28482	MAPK1	T569	Q575H	575	Missense	distal	6	no	11.581	11.563	EPSD	ICGC;COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q05209	PTPN12	P28482	MAPK1	S571	S567T	567	Missense	distal	-4	no	13.707	13.477	PhosphoSitePlus	ICGC;COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q05209	PTPN12	P28482	MAPK1	S571	Q575H	575	Missense	distal	4	no	13.707	13.640	PhosphoSitePlus	ICGC;COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q05209	PTPN12	P28482	MAPK1	T578	Q575H	575	Missense	distal	-3	no	13.878	13.825	EPSD	ICGC;COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q96Q27	ASB2	P28482	MAPK1	S28	E27K	27	Missense	proximal	-1	no	9.722	9.750	EPSD	ICGC;COSMIC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q96Q27	ASB2	P28482	MAPK1	S29	E27K	27	Missense	proximal	-2	no	14.784	14.744	EPSD	ICGC;COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q07820	MCL1	P28482	MAPK1	T92	V86L	86	Missense	distal	-6	no	13.543	13.538	EPSD	ICGC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q07820	MCL1	P28482	MAPK1	T92	E85D	85	Missense	distal	-7	no	13.543	13.536	EPSD	ICGC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q07820	MCL1	P28482	MAPK1	T92	A94T	94	Missense	proximal	2	no	13.543	13.623	EPSD	ICGC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q07820	MCL1	P28482	MAPK1	T92	R95S	95	Missense	distal	3	no	13.543	13.567	EPSD	ICGC;COSMIC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q07820	MCL1	P28482	MAPK1	T92	T92P	92	Missense	central	0	yes	13.543	0.000	EPSD	ICGC;COSMIC	8.102	Loss
CMGC_MAPK_ERK1_MAPK1_ST	Q07820	MCL1	P28482	MAPK1	S121	I119V	119	Missense	proximal	-2	no	14.752	14.774	EPSD	ICGC;COSMIC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q07820	MCL1	P28482	MAPK1	S121	E125D	125	Missense	distal	4	no	14.752	14.682	EPSD	ICGC;COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q07820	MCL1	P28482	MAPK1	T163	T156A	156	Missense	distal	-7	no	17.184	17.199	PhosphoSitePlus	ICGC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q07820	MCL1	P28482	MAPK1	T163	P161S	161	Missense	proximal	-2	no	17.184	14.350	PhosphoSitePlus	ICGC;COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q07820	MCL1	P28482	MAPK1	T163	P166Q	166	Missense	distal	3	no	17.184	17.252	PhosphoSitePlus	ICGC;COSMIC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P68400	CSNK2A1	P28482	MAPK1	T13	H18Q	18	Missense	distal	5	no	8.190	8.196	EPSD	ICGC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P68400	CSNK2A1	P28482	MAPK1	T17	H18Q	18	Missense	proximal	1	no	9.899	9.229	EPSD	ICGC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P68400	CSNK2A1	P28482	MAPK1	T344	T344M	344	Missense	central	0	yes	15.195	0.000	EPSD	ICGC;COSMIC	8.102	Loss
CMGC_MAPK_ERK1_MAPK1_ST	P68400	CSNK2A1	P28482	MAPK1	T344	A349T	349	Missense	distal	5	no	15.195	15.281	EPSD	ICGC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P68400	CSNK2A1	P28482	MAPK1	T360	P366H	366	Missense	distal	6	no	15.211	14.905	EPSD;PhosphoSitePlus	ICGC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P68400	CSNK2A1	P28482	MAPK1	T360	I355M	355	Missense	distal	-5	no	15.211	15.154	EPSD;PhosphoSitePlus	ICGC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P68400	CSNK2A1	P28482	MAPK1	S362	P366H	366	Missense	distal	4	no	14.277	14.102	PhosphoSitePlus;EPSD	ICGC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P68400	CSNK2A1	P28482	MAPK1	S362	I355M	355	Missense	distal	-7	no	14.277	14.287	PhosphoSitePlus;EPSD	ICGC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P68400	CSNK2A1	P28482	MAPK1	S370	P366H	366	Missense	distal	-4	no	16.132	15.891	EPSD	ICGC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q08493	PDE4C	P28482	MAPK1	S100	R105Q	105	Missense	distal	5	no	13.736	13.566	EPSD	ICGC;COSMIC;GDSC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q08493	PDE4C	P28482	MAPK1	S100	A94D	94	Missense	distal	-6	no	13.736	13.798	EPSD	ICGC;COSMIC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q08493	PDE4C	P28482	MAPK1	S100	R93M	93	Missense	distal	-7	no	13.736	13.720	EPSD	ICGC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q08493	PDE4C	P28482	MAPK1	S100	D96Y	96	Missense	distal	-4	no	13.736	13.078	EPSD	ICGC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q08493	PDE4C	P28482	MAPK1	S100	Q98H	98	Missense	proximal	-2	no	13.736	13.975	EPSD	ICGC;COSMIC;GDSC;CCLE	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q08493	PDE4C	P28482	MAPK1	S131	S136F	136	Missense	distal	5	no	14.514	14.317	EPSD	ICGC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q96LC9	BMF	P28482	MAPK1	S74	S77F	77	Missense	distal	3	no	15.634	15.696	PhosphoSitePlus;EPSD	ICGC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q96LC9	BMF	P28482	MAPK1	S77	S77F	77	Missense	central	0	yes	18.767	0.000	EPSD;PhosphoSitePlus	ICGC	8.102	Loss
CMGC_MAPK_ERK1_MAPK1_ST	Q96LC9	BMF	P28482	MAPK1	S109	P105L	105	Missense	distal	-4	no	9.393	9.088	EPSD	ICGC;COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q15746	MYLK	P28482	MAPK1	S16	P21H	21	Missense	distal	5	no	8.118	7.991	EPSD	ICGC;COSMIC	8.102	Loss
CMGC_MAPK_ERK1_MAPK1_ST	Q15746	MYLK	P28482	MAPK1	S16	R23T	23	Missense	distal	7	no	8.118	8.266	EPSD	ICGC;COSMIC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q15746	MYLK	P28482	MAPK1	S16	P21S	21	Missense	distal	5	no	8.118	8.136	EPSD	ICGC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q15746	MYLK	P28482	MAPK1	S299	S299I	299	Missense	central	0	yes	12.013	0.000	EPSD	ICGC	8.102	Loss
CMGC_MAPK_ERK1_MAPK1_ST	Q15746	MYLK	P28482	MAPK1	S299	A292S	292	Missense	distal	-7	no	12.013	12.011	EPSD	ICGC;COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q15746	MYLK	P28482	MAPK1	S305	S299I	299	Missense	distal	-6	no	13.986	13.884	EPSD	ICGC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q15746	MYLK	P28482	MAPK1	S305	S312R	312	Missense	distal	7	no	13.986	13.989	EPSD	ICGC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q15746	MYLK	P28482	MAPK1	S328	Q334H	334	Missense	distal	6	no	14.314	14.296	EPSD	ICGC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q15746	MYLK	P28482	MAPK1	T335	T341S	341	Missense	distal	6	no	14.658	14.868	EPSD	ICGC;COSMIC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q15746	MYLK	P28482	MAPK1	T335	Q334H	334	Missense	proximal	-1	no	14.658	14.656	EPSD	ICGC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q15746	MYLK	P28482	MAPK1	S365	P359Q	359	Missense	distal	-6	no	15.138	15.123	EPSD	ICGC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q15746	MYLK	P28482	MAPK1	S365	A358E	358	Missense	distal	-7	no	15.138	15.146	EPSD	ICGC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q15746	MYLK	P28482	MAPK1	S515	P514S	514	Missense	proximal	-1	no	9.945	9.902	EPSD	ICGC;COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q15746	MYLK	P28482	MAPK1	S947	E942Q	942	Missense	distal	-5	no	14.753	14.853	EPSD	ICGC;COSMIC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q15746	MYLK	P28482	MAPK1	S947	R954S	954	Missense	distal	7	no	14.753	14.750	EPSD	ICGC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q15746	MYLK	P28482	MAPK1	S947	E941K	941	Missense	distal	-6	no	14.753	14.727	EPSD	ICGC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q15746	MYLK	P28482	MAPK1	T978	D980E	980	Missense	proximal	2	no	16.073	16.021	EPSD	ICGC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q15746	MYLK	P28482	MAPK1	T1230	K1233T	1233	Missense	distal	3	no	14.393	14.457	EPSD	ICGC;COSMIC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q15746	MYLK	P28482	MAPK1	T1230	P1228H	1228	Missense	proximal	-2	no	14.393	11.638	EPSD	ICGC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q15746	MYLK	P28482	MAPK1	T1230	P1232T	1232	Missense	proximal	2	no	14.393	14.343	EPSD	ICGC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q15746	MYLK	P28482	MAPK1	T1230	T1230K	1230	Missense	central	0	yes	14.393	0.000	EPSD	ICGC	8.102	Loss
CMGC_MAPK_ERK1_MAPK1_ST	Q15746	MYLK	P28482	MAPK1	T1230	M1236V	1236	Missense	distal	6	no	14.393	14.612	EPSD	ICGC;COSMIC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q15746	MYLK	P28482	MAPK1	T1337	P1334L	1334	Missense	distal	-3	no	11.797	11.414	EPSD	ICGC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q15746	MYLK	P28482	MAPK1	T1337	P1331T	1331	Missense	distal	-6	no	11.797	11.748	EPSD	ICGC;COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q15746	MYLK	P28482	MAPK1	T1337	G1336D	1336	Missense	proximal	-1	no	11.797	11.796	EPSD	ICGC;COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q15746	MYLK	P28482	MAPK1	T1624	F1622S	1622	Missense	proximal	-2	no	12.422	12.229	EPSD	ICGC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q15746	MYLK	P28482	MAPK1	T1624	F1622V	1622	Missense	proximal	-2	no	12.422	13.190	EPSD	ICGC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q15746	MYLK	P28482	MAPK1	S1659	M1662V	1662	Missense	distal	3	no	12.634	12.606	EPSD	ICGC;COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	O75581	LRP6	P28482	MAPK1	S646	A640V	640	Missense	distal	-6	no	8.517	8.470	EPSD	ICGC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	O75581	LRP6	P28482	MAPK1	S646	A640E	640	Missense	distal	-6	no	8.517	8.567	EPSD	ICGC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q8IX03	WWC1	P28482	MAPK1	S270	S268I	268	Missense	proximal	-2	no	7.552	8.492	EPSD	ICGC;COSMIC	8.102	Gain
CMGC_MAPK_ERK1_MAPK1_ST	Q8IX03	WWC1	P28482	MAPK1	S358	R355C	355	Missense	distal	-3	no	15.100	14.417	EPSD	ICGC;COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q8IX03	WWC1	P28482	MAPK1	S358	K352R	352	Missense	distal	-6	no	15.100	15.123	EPSD	ICGC;COSMIC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q8IX03	WWC1	P28482	MAPK1	S438	L442I	442	Missense	distal	4	no	14.144	14.087	EPSD	ICGC;COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q8IX03	WWC1	P28482	MAPK1	S441	L442I	442	Missense	proximal	1	no	9.221	8.212	EPSD	ICGC;COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q8IX03	WWC1	P28482	MAPK1	T527	T527I	527	Missense	central	0	yes	15.324	0.000	EPSD	ICGC;COSMIC	8.102	Loss
CMGC_MAPK_ERK1_MAPK1_ST	Q8IX03	WWC1	P28482	MAPK1	T527	A520S	520	Missense	distal	-7	no	15.324	15.323	EPSD	ICGC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q8IX03	WWC1	P28482	MAPK1	S535	P536Q	536	Missense	proximal	1	no	13.626	5.133	EPSD	ICGC;COSMIC	8.102	Loss
CMGC_MAPK_ERK1_MAPK1_ST	Q8IX03	WWC1	P28482	MAPK1	S535	S539P	539	Missense	distal	4	no	13.626	13.637	EPSD	ICGC;COSMIC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q8IX03	WWC1	P28482	MAPK1	S535	S542T	542	Missense	distal	7	no	13.626	13.779	EPSD	ICGC;COSMIC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q8IX03	WWC1	P28482	MAPK1	S535	S535F	535	Missense	central	0	yes	13.626	0.000	EPSD	ICGC	8.102	Loss
CMGC_MAPK_ERK1_MAPK1_ST	Q8IX03	WWC1	P28482	MAPK1	S535	S541F	541	Missense	distal	6	no	13.626	13.186	EPSD	ICGC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q8IX03	WWC1	P28482	MAPK1	S542	P536Q	536	Missense	distal	-6	no	15.040	15.024	EPSD;PhosphoSitePlus	ICGC;COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q8IX03	WWC1	P28482	MAPK1	S542	S539P	539	Missense	distal	-3	no	15.040	15.216	EPSD;PhosphoSitePlus	ICGC;COSMIC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q8IX03	WWC1	P28482	MAPK1	S542	S535F	535	Missense	distal	-7	no	15.040	15.020	EPSD;PhosphoSitePlus	ICGC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q8IX03	WWC1	P28482	MAPK1	S542	S541F	541	Missense	proximal	-1	no	15.040	14.993	EPSD;PhosphoSitePlus	ICGC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q8IX03	WWC1	P28482	MAPK1	S548	L555V	555	Missense	distal	7	no	17.430	17.425	PhosphoSitePlus;EPSD	ICGC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q8IX03	WWC1	P28482	MAPK1	S548	P554L	554	Missense	distal	6	no	17.430	17.024	PhosphoSitePlus;EPSD	ICGC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q8IX03	WWC1	P28482	MAPK1	S548	S542T	542	Missense	distal	-6	no	17.430	17.407	PhosphoSitePlus;EPSD	ICGC;COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q8IX03	WWC1	P28482	MAPK1	S548	S541F	541	Missense	distal	-7	no	17.430	17.410	PhosphoSitePlus;EPSD	ICGC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q8IX03	WWC1	P28482	MAPK1	S876	M879R	879	Missense	distal	3	no	13.752	13.713	EPSD	ICGC;COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q8IX03	WWC1	P28482	MAPK1	T912	R908W	908	Missense	distal	-4	no	12.850	11.907	EPSD	ICGC;COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q8IX03	WWC1	P28482	MAPK1	T912	V910L	910	Missense	proximal	-2	no	12.850	12.805	EPSD	ICGC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P01106	MYC	P28482	MAPK1	S71	P72S	72	Missense	proximal	1	no	14.405	5.010	EPSD	ICGC;COSMIC;GDSC	8.102	Loss
CMGC_MAPK_ERK1_MAPK1_ST	P01106	MYC	P28482	MAPK1	S71	P72A	72	Missense	proximal	1	no	14.405	6.774	EPSD	ICGC;COSMIC	8.102	Loss
CMGC_MAPK_ERK1_MAPK1_ST	P01106	MYC	P28482	MAPK1	S71	P72L	72	Missense	proximal	1	no	14.405	5.595	EPSD	ICGC;COSMIC	8.102	Loss
CMGC_MAPK_ERK1_MAPK1_ST	P01106	MYC	P28482	MAPK1	S71	P72T	72	Missense	proximal	1	no	14.405	5.906	EPSD	ICGC;COSMIC;GDSC	8.102	Loss
CMGC_MAPK_ERK1_MAPK1_ST	P01106	MYC	P28482	MAPK1	T78	P72S	72	Missense	distal	-6	no	15.642	15.616	EPSD	ICGC;COSMIC;GDSC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P01106	MYC	P28482	MAPK1	T78	P72A	72	Missense	distal	-6	no	15.642	15.602	EPSD	ICGC;COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P01106	MYC	P28482	MAPK1	T78	P72L	72	Missense	distal	-6	no	15.642	15.550	EPSD	ICGC;COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P01106	MYC	P28482	MAPK1	T78	P72T	72	Missense	distal	-6	no	15.642	15.592	EPSD	ICGC;COSMIC;GDSC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P14784	IL2RB	P28482	MAPK1	T282	P285H	285	Missense	distal	3	no	10.709	10.798	EPSD	ICGC;COSMIC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P14784	IL2RB	P28482	MAPK1	S431	L429F	429	Missense	proximal	-2	no	13.075	12.351	EPSD	ICGC;COSMIC;CCLE	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P14784	IL2RB	P28482	MAPK1	S431	D426E	426	Missense	distal	-5	no	13.075	13.030	EPSD	ICGC;COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P14784	IL2RB	P28482	MAPK1	S458	R465G	465	Missense	distal	7	no	8.389	8.454	EPSD	ICGC;COSMIC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P14784	IL2RB	P28482	MAPK1	S458	R465I	465	Missense	distal	7	no	8.389	8.933	EPSD	ICGC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P14784	IL2RB	P28482	MAPK1	S458	V463I	463	Missense	distal	5	no	8.389	8.214	EPSD	ICGC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P14784	IL2RB	P28482	MAPK1	T476	P471T	471	Missense	distal	-5	no	15.778	15.881	PhosphoSitePlus	ICGC;COSMIC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P14784	IL2RB	P28482	MAPK1	T476	P471L	471	Missense	distal	-5	no	15.778	15.927	PhosphoSitePlus	ICGC;COSMIC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P14784	IL2RB	P28482	MAPK1	T476	L472M	472	Missense	distal	-4	no	15.778	15.617	PhosphoSitePlus	ICGC;COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P14784	IL2RB	P28482	MAPK1	T533	L531M	531	Missense	proximal	-2	no	8.864	6.767	EPSD	ICGC;COSMIC	8.102	Loss
CMGC_MAPK_ERK1_MAPK1_ST	P14784	IL2RB	P28482	MAPK1	S538	Q545E	545	Missense	distal	7	no	8.211	8.033	EPSD	ICGC;COSMIC	8.102	Loss
CMGC_MAPK_ERK1_MAPK1_ST	P14784	IL2RB	P28482	MAPK1	S538	L531M	531	Missense	distal	-7	no	8.211	8.202	EPSD	ICGC;COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P49841	GSK3B	P28482	MAPK1	T7	A11S	11	Missense	distal	4	no	8.162	8.255	EPSD	ICGC;COSMIC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P49841	GSK3B	P28482	MAPK1	T43	D49E	49	Missense	distal	6	no	15.197	15.276	PhosphoSitePlus	ICGC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P49841	GSK3B	P28482	MAPK1	S215	S219Y	219	Missense	distal	4	no	8.103	7.909	EPSD	ICGC;COSMIC	8.102	Loss
CMGC_MAPK_ERK1_MAPK1_ST	P49841	GSK3B	P28482	MAPK1	S215	P212T	212	Missense	distal	-3	no	8.103	7.894	EPSD	ICGC	8.102	Loss
CMGC_MAPK_ERK1_MAPK1_ST	P49841	GSK3B	P28482	MAPK1	T275	I270V	270	Missense	distal	-5	no	14.438	14.325	EPSD	ICGC;COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P49841	GSK3B	P28482	MAPK1	T275	R278K	278	Missense	distal	3	no	14.438	14.390	EPSD	ICGC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P49841	GSK3B	P28482	MAPK1	T275	L273R	273	Missense	proximal	-2	no	14.438	14.537	EPSD	ICGC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P49841	GSK3B	P28482	MAPK1	T275	L273M	273	Missense	proximal	-2	no	14.438	12.341	EPSD	ICGC;COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P49841	GSK3B	P28482	MAPK1	T324	R319H	319	Missense	distal	-5	no	14.097	14.175	EPSD	ICGC;COSMIC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P49841	GSK3B	P28482	MAPK1	T324	A327P	327	Missense	distal	3	no	14.097	14.019	EPSD	ICGC;COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P49841	GSK3B	P28482	MAPK1	T324	R328L	328	Missense	distal	4	no	14.097	14.010	EPSD	ICGC;COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P49841	GSK3B	P28482	MAPK1	T324	P331L	331	Missense	distal	7	no	14.097	14.397	EPSD	ICGC;COSMIC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P49841	GSK3B	P28482	MAPK1	T324	R328Q	328	Missense	distal	4	no	14.097	14.023	EPSD	ICGC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P49841	GSK3B	P28482	MAPK1	T324	L321M	321	Missense	distal	-3	no	14.097	14.044	EPSD	ICGC;COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P49841	GSK3B	P28482	MAPK1	T390	S389P	389	Missense	proximal	-1	no	10.997	11.041	EPSD	ICGC;COSMIC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P49841	GSK3B	P28482	MAPK1	T390	A397T	397	Missense	distal	7	no	10.997	10.968	EPSD	ICGC;COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P49841	GSK3B	P28482	MAPK1	T390	R383Q	383	Missense	distal	-7	no	10.997	11.005	EPSD	ICGC;COSMIC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P49841	GSK3B	P28482	MAPK1	S413	G406R	406	Missense	distal	-7	no	8.752	8.765	EPSD	ICGC;COSMIC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P49841	GSK3B	P28482	MAPK1	S413	S415T	415	Missense	proximal	2	no	8.752	8.729	EPSD	ICGC;COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P06239	LCK	P28482	MAPK1	S42	G41C	41	Missense	proximal	-1	no	9.303	9.236	EPSD	ICGC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P06239	LCK	P28482	MAPK1	S281	S281N	281	Missense	central	0	yes	14.176	0.000	EPSD	ICGC;COSMIC	8.102	Loss
CMGC_MAPK_ERK1_MAPK1_ST	P06239	LCK	P28482	MAPK1	S281	S281I	281	Missense	central	0	yes	14.176	0.000	EPSD	ICGC	8.102	Loss
CMGC_MAPK_ERK1_MAPK1_ST	P42702	LIFR	P28482	MAPK1	S534	Q527K	527	Missense	distal	-7	no	16.663	16.658	EPSD	ICGC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P42702	LIFR	P28482	MAPK1	T904	N906D	906	Missense	proximal	2	no	15.958	16.018	EPSD	ICGC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P42702	LIFR	P28482	MAPK1	S927	E931G	931	Missense	distal	4	no	14.180	14.157	EPSD	ICGC;COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P42702	LIFR	P28482	MAPK1	S927	R932C	932	Missense	distal	5	no	14.180	13.748	EPSD	ICGC;COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P42702	LIFR	P28482	MAPK1	S927	E924K	924	Missense	distal	-3	no	14.180	14.102	EPSD	ICGC;COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P42702	LIFR	P28482	MAPK1	S927	V929A	929	Missense	proximal	2	no	14.180	14.104	EPSD	ICGC;COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P42702	LIFR	P28482	MAPK1	S1041	P1042Q	1042	Missense	proximal	1	no	15.138	6.644	EPSD	ICGC;COSMIC	8.102	Loss
CMGC_MAPK_ERK1_MAPK1_ST	P42702	LIFR	P28482	MAPK1	S1044	P1042Q	1042	Missense	proximal	-2	no	18.089	15.095	PhosphoSitePlus	ICGC;COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P42702	LIFR	P28482	MAPK1	S1047	P1042Q	1042	Missense	distal	-5	no	8.706	8.831	EPSD	ICGC;COSMIC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P42702	LIFR	P28482	MAPK1	S1056	P1060L	1060	Missense	distal	4	no	10.056	9.936	EPSD	ICGC;COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P42702	LIFR	P28482	MAPK1	S1059	P1060L	1060	Missense	proximal	1	no	13.739	4.929	EPSD	ICGC;COSMIC	8.102	Loss
CMGC_MAPK_ERK1_MAPK1_ST	P42702	LIFR	P28482	MAPK1	S1062	Q1067K	1067	Missense	distal	5	no	8.299	8.334	EPSD	ICGC;COSMIC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P42702	LIFR	P28482	MAPK1	S1062	P1060L	1060	Missense	proximal	-2	no	8.299	6.381	EPSD	ICGC;COSMIC	8.102	Loss
CMGC_MAPK_ERK1_MAPK1_ST	P42702	LIFR	P28482	MAPK1	S1077	P1071H	1071	Missense	distal	-6	no	15.325	15.251	EPSD	ICGC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P42702	LIFR	P28482	MAPK1	S1077	G1084R	1084	Missense	distal	7	no	15.325	15.260	EPSD	ICGC;COSMIC;GDSC;CCLE	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P42702	LIFR	P28482	MAPK1	S1086	G1084R	1084	Missense	proximal	-2	no	7.713	9.088	EPSD	ICGC;COSMIC;GDSC;CCLE	8.102	Gain
CMGC_MAPK_ERK1_MAPK1_ST	Q14247	CTTN	P28482	MAPK1	T24	D25Y	25	Missense	proximal	1	no	7.069	8.756	EPSD	ICGC	8.102	Gain
CMGC_MAPK_ERK1_MAPK1_ST	Q14247	CTTN	P28482	MAPK1	T68	L69P	69	Missense	proximal	1	no	3.636	12.446	EPSD	ICGC	8.102	Gain
CMGC_MAPK_ERK1_MAPK1_ST	Q14247	CTTN	P28482	MAPK1	T401	T401M	401	Missense	central	0	yes	11.749	0.000	EPSD	ICGC;COSMIC	8.102	Loss
CMGC_MAPK_ERK1_MAPK1_ST	Q14247	CTTN	P28482	MAPK1	T401	T401A	401	Missense	central	0	yes	11.749	0.000	EPSD	ICGC	8.102	Loss
CMGC_MAPK_ERK1_MAPK1_ST	Q14247	CTTN	P28482	MAPK1	T401	S405L	405	Missense	distal	4	no	11.749	11.640	EPSD	ICGC;COSMIC;GDSC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q14247	CTTN	P28482	MAPK1	T401	A407T	407	Missense	distal	6	no	11.749	11.836	EPSD	ICGC;COSMIC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q14247	CTTN	P28482	MAPK1	S405	E412K	412	Missense	distal	7	no	15.769	15.777	PhosphoSitePlus;EPSD	ICGC;COSMIC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q14247	CTTN	P28482	MAPK1	S405	T401M	401	Missense	distal	-4	no	15.769	15.617	PhosphoSitePlus;EPSD	ICGC;COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q14247	CTTN	P28482	MAPK1	S405	T401A	401	Missense	distal	-4	no	15.769	15.789	PhosphoSitePlus;EPSD	ICGC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q14247	CTTN	P28482	MAPK1	S405	S405L	405	Missense	central	0	yes	15.769	0.000	PhosphoSitePlus;EPSD	ICGC;COSMIC;GDSC	8.102	Loss
CMGC_MAPK_ERK1_MAPK1_ST	Q14247	CTTN	P28482	MAPK1	S405	A407T	407	Missense	proximal	2	no	15.769	15.848	PhosphoSitePlus;EPSD	ICGC;COSMIC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q14247	CTTN	P28482	MAPK1	S418	E412K	412	Missense	distal	-6	no	16.346	16.320	EPSD;PhosphoSitePlus	ICGC;COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q14247	CTTN	P28482	MAPK1	S418	L415P	415	Missense	distal	-3	no	16.346	16.730	EPSD;PhosphoSitePlus	ICGC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q14247	CTTN	P28482	MAPK1	S418	A424V	424	Missense	distal	6	no	16.346	16.428	EPSD;PhosphoSitePlus	ICGC;COSMIC;GDSC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q14247	CTTN	P28482	MAPK1	S426	A424V	424	Missense	proximal	-2	no	8.657	9.931	EPSD	ICGC;COSMIC;GDSC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q00059	TFAM	P28482	MAPK1	S34	R40M	40	Missense	distal	6	no	9.769	9.443	EPSD	ICGC;COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q00059	TFAM	P28482	MAPK1	T77	A75E	75	Missense	proximal	-2	no	7.423	8.190	EPSD	ICGC;COSMIC	8.102	Gain
CMGC_MAPK_ERK1_MAPK1_ST	P00558	PGK1	P28482	MAPK1	S203	A200V	200	Missense	distal	-3	no	14.700	14.760	PhosphoSitePlus	ICGC;COSMIC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P00558	PGK1	P28482	MAPK1	S203	A198T	198	Missense	distal	-5	no	14.700	14.678	PhosphoSitePlus	ICGC;COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P46527	CDKN1B	P28482	MAPK1	S10	N8K	8	Missense	proximal	-2	no	14.720	15.120	PhosphoSitePlus;EPSD	ICGC;COSMIC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P46527	CDKN1B	P28482	MAPK1	S178	V184M	184	Missense	distal	6	no	16.020	15.801	EPSD;PhosphoSitePlus	ICGC;COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P46527	CDKN1B	P28482	MAPK1	S178	G182C	182	Missense	distal	4	no	16.020	15.787	EPSD;PhosphoSitePlus	ICGC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P46527	CDKN1B	P28482	MAPK1	S178	G177V	177	Missense	proximal	-1	no	16.020	16.048	EPSD;PhosphoSitePlus	ICGC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P46527	CDKN1B	P28482	MAPK1	S178	S178F	178	Missense	central	0	yes	16.020	0.000	EPSD;PhosphoSitePlus	ICGC;COSMIC	8.102	Loss
CMGC_MAPK_ERK1_MAPK1_ST	P46527	CDKN1B	P28482	MAPK1	T187	V184M	184	Missense	distal	-3	no	15.791	15.661	EPSD;PhosphoSitePlus	ICGC;COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P46527	CDKN1B	P28482	MAPK1	T187	G192V	192	Missense	distal	5	no	15.791	15.668	EPSD;PhosphoSitePlus	ICGC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P46527	CDKN1B	P28482	MAPK1	T187	G182C	182	Missense	distal	-5	no	15.791	16.001	EPSD;PhosphoSitePlus	ICGC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P46527	CDKN1B	P28482	MAPK1	T187	P191H	191	Missense	distal	4	no	15.791	15.616	EPSD;PhosphoSitePlus	ICGC;COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P11308	ERG	P28482	MAPK1	S222	A228S	228	Missense	distal	6	no	13.432	13.729	EPSD;PhosphoSitePlus	ICGC;COSMIC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P22736	NR4A1	P28482	MAPK1	T10	P15L	15	Missense	distal	5	no	14.133	13.920	EPSD	ICGC;COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P22736	NR4A1	P28482	MAPK1	S14	P15L	15	Missense	proximal	1	no	15.054	6.244	EPSD	ICGC;COSMIC	8.102	Loss
CMGC_MAPK_ERK1_MAPK1_ST	P22736	NR4A1	P28482	MAPK1	S95	S89F	89	Missense	distal	-6	no	12.717	12.633	EPSD	ICGC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P22736	NR4A1	P28482	MAPK1	S140	S137W	137	Missense	distal	-3	no	13.969	13.428	EPSD	ICGC;COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P22736	NR4A1	P28482	MAPK1	T143	S137W	137	Missense	distal	-6	no	18.045	17.859	EPSD	ICGC;COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P22736	NR4A1	P28482	MAPK1	S152	P153H	153	Missense	proximal	1	no	14.120	6.296	EPSD	ICGC;COSMIC	8.102	Loss
CMGC_MAPK_ERK1_MAPK1_ST	P22736	NR4A1	P28482	MAPK1	S360	P357S	357	Missense	distal	-3	no	13.556	13.379	EPSD	ICGC;COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P22736	NR4A1	P28482	MAPK1	S360	L364R	364	Missense	distal	4	no	13.556	13.643	EPSD	ICGC;COSMIC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P22736	NR4A1	P28482	MAPK1	S360	D358N	358	Missense	proximal	-2	no	13.556	14.037	EPSD	ICGC;COSMIC;CCLE	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P22736	NR4A1	P28482	MAPK1	S431	D436Y	436	Missense	distal	5	no	13.905	13.592	PhosphoSitePlus	ICGC;COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P27708	CAD	P28482	MAPK1	T456	H458Q	458	Missense	proximal	2	no	15.215	15.166	PhosphoSitePlus	ICGC;COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P27708	CAD	P28482	MAPK1	T456	V460A	460	Missense	distal	4	no	15.215	15.221	PhosphoSitePlus	ICGC;COSMIC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P27708	CAD	P28482	MAPK1	T475	G477A	477	Missense	proximal	2	no	8.391	8.243	EPSD	ICGC;COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P27708	CAD	P28482	MAPK1	T475	R468L	468	Missense	distal	-7	no	8.391	8.384	EPSD	ICGC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P27708	CAD	P28482	MAPK1	T475	G471C	471	Missense	distal	-4	no	8.391	8.013	EPSD	ICGC	8.102	Loss
CMGC_MAPK_ERK1_MAPK1_ST	P27708	CAD	P28482	MAPK1	T504	G498V	498	Missense	distal	-6	no	14.739	14.696	EPSD	ICGC;COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P27708	CAD	P28482	MAPK1	T504	R500Q	500	Missense	distal	-4	no	14.739	14.636	EPSD	ICGC;COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P27708	CAD	P28482	MAPK1	T504	R500W	500	Missense	distal	-4	no	14.739	13.796	EPSD	ICGC;COSMIC;GDSC;CCLE	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q00613	HSF1	P28482	MAPK1	S241	P239L	239	Missense	proximal	-2	no	8.721	6.803	EPSD	ICGC;CCLE	8.102	Loss
CMGC_MAPK_ERK1_MAPK1_ST	Q00613	HSF1	P28482	MAPK1	S244	P239L	239	Missense	distal	-5	no	13.950	14.099	EPSD	ICGC;CCLE	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q00613	HSF1	P28482	MAPK1	S275	A278T	278	Missense	distal	3	no	17.140	17.123	EPSD	ICGC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q00613	HSF1	P28482	MAPK1	S279	A278T	278	Missense	proximal	-1	no	12.370	12.365	EPSD	ICGC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q00613	HSF1	P28482	MAPK1	S419	S421L	421	Missense	proximal	2	no	14.430	14.310	EPSD	ICGC;COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q00613	HSF1	P28482	MAPK1	S419	S419G	419	Missense	central	0	yes	14.430	0.000	EPSD	ICGC;COSMIC	8.102	Loss
CMGC_MAPK_ERK1_MAPK1_ST	Q00613	HSF1	P28482	MAPK1	S444	A437S	437	Missense	distal	-7	no	16.077	16.075	EPSD	ICGC;COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q969H0	FBXW7	P28482	MAPK1	S25	R20I	20	Missense	distal	-5	no	11.030	11.191	EPSD	ICGC;COSMIC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q969H0	FBXW7	P28482	MAPK1	S25	P23S	23	Missense	proximal	-2	no	11.030	8.196	EPSD	ICGC;COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q969H0	FBXW7	P28482	MAPK1	S26	R20I	20	Missense	distal	-6	no	8.758	8.622	EPSD	ICGC;COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q969H0	FBXW7	P28482	MAPK1	S26	P23S	23	Missense	distal	-3	no	8.758	8.581	EPSD	ICGC;COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q969H0	FBXW7	P28482	MAPK1	T205	L212R	212	Missense	distal	7	no	12.937	12.652	PhosphoSitePlus	ICGC;COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q969H0	FBXW7	P28482	MAPK1	T205	P201T	201	Missense	distal	-4	no	12.937	12.624	PhosphoSitePlus	ICGC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q969H0	FBXW7	P28482	MAPK1	T205	P206T	206	Missense	proximal	1	no	12.937	4.438	PhosphoSitePlus	ICGC	8.102	Loss
CMGC_MAPK_ERK1_MAPK1_ST	Q969H0	FBXW7	P28482	MAPK1	T205	T205K	205	Missense	central	0	yes	12.937	0.000	PhosphoSitePlus	ICGC	8.102	Loss
CMGC_MAPK_ERK1_MAPK1_ST	Q969H0	FBXW7	P28482	MAPK1	T205	V200L	200	Missense	distal	-5	no	12.937	12.990	PhosphoSitePlus	ICGC;COSMIC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q969H0	FBXW7	P28482	MAPK1	T205	G198W	198	Missense	distal	-7	no	12.937	12.899	PhosphoSitePlus	ICGC;COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q969H0	FBXW7	P28482	MAPK1	S372	G368R	368	Missense	distal	-4	no	14.301	14.562	EPSD	ICGC;COSMIC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q969H0	FBXW7	P28482	MAPK1	S372	V375L	375	Missense	distal	3	no	14.301	14.333	EPSD	ICGC;COSMIC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q969H0	FBXW7	P28482	MAPK1	S688	G687E	687	Missense	proximal	-1	no	8.071	8.111	EPSD	ICGC;COSMIC	8.102	Gain
CMGC_MAPK_ERK1_MAPK1_ST	Q15750	TAB1	P28482	MAPK1	S16	P15Q	15	Missense	proximal	-1	no	10.112	10.071	EPSD	ICGC;COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q15750	TAB1	P28482	MAPK1	T376	S373I	373	Missense	distal	-3	no	11.228	10.964	EPSD	ICGC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q15750	TAB1	P28482	MAPK1	T376	P381S	381	Missense	distal	5	no	11.228	11.246	EPSD	ICGC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q15750	TAB1	P28482	MAPK1	T376	S378I	378	Missense	proximal	2	no	11.228	11.085	EPSD	ICGC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q15750	TAB1	P28482	MAPK1	T376	Q374H	374	Missense	proximal	-2	no	11.228	11.467	EPSD	ICGC;COSMIC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q15750	TAB1	P28482	MAPK1	T376	S378R	378	Missense	proximal	2	no	11.228	11.370	EPSD	ICGC;COSMIC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q15750	TAB1	P28482	MAPK1	T376	Q374K	374	Missense	proximal	-2	no	11.228	11.803	EPSD	ICGC;COSMIC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q15750	TAB1	P28482	MAPK1	S378	S373I	373	Missense	distal	-5	no	13.001	13.136	EPSD	ICGC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q15750	TAB1	P28482	MAPK1	S378	P381S	381	Missense	distal	3	no	13.001	13.070	EPSD	ICGC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q15750	TAB1	P28482	MAPK1	S378	S378I	378	Missense	central	0	yes	13.001	0.000	EPSD	ICGC	8.102	Loss
CMGC_MAPK_ERK1_MAPK1_ST	Q15750	TAB1	P28482	MAPK1	S378	Q374H	374	Missense	distal	-4	no	13.001	12.952	EPSD	ICGC;COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q15750	TAB1	P28482	MAPK1	S378	S378R	378	Missense	central	0	yes	13.001	0.000	EPSD	ICGC;COSMIC	8.102	Loss
CMGC_MAPK_ERK1_MAPK1_ST	Q15750	TAB1	P28482	MAPK1	S378	Q374K	374	Missense	distal	-4	no	13.001	13.183	EPSD	ICGC;COSMIC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q15750	TAB1	P28482	MAPK1	T431	L434I	434	Missense	distal	3	no	12.012	12.050	EPSD	ICGC;COSMIC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q15750	TAB1	P28482	MAPK1	T431	S438R	438	Missense	distal	7	no	12.012	12.016	EPSD	ICGC;COSMIC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q15750	TAB1	P28482	MAPK1	S438	L434I	434	Missense	distal	-4	no	13.407	13.041	PhosphoSitePlus	ICGC;COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q15750	TAB1	P28482	MAPK1	S438	S438R	438	Missense	central	0	yes	13.407	0.000	PhosphoSitePlus	ICGC;COSMIC	8.102	Loss
CMGC_MAPK_ERK1_MAPK1_ST	Q15750	TAB1	P28482	MAPK1	S492	Y488S	488	Missense	distal	-4	no	8.195	8.784	EPSD	ICGC;COSMIC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q15750	TAB1	P28482	MAPK1	S492	E486D	486	Missense	distal	-6	no	8.195	8.207	EPSD	ICGC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q15750	TAB1	P28482	MAPK1	S492	R489S	489	Missense	distal	-3	no	8.195	8.038	EPSD	ICGC;COSMIC	8.102	Loss
CMGC_MAPK_ERK1_MAPK1_ST	Q9Y6K1	DNMT3A	P28482	MAPK1	S15	E21K	21	Missense	distal	6	no	8.539	8.563	EPSD	ICGC;COSMIC;GDSC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q9Y6K1	DNMT3A	P28482	MAPK1	S15	D11E	11	Missense	distal	-4	no	8.539	8.525	EPSD	ICGC;COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q9Y6K1	DNMT3A	P28482	MAPK1	T65	S62R	62	Missense	distal	-3	no	13.845	14.002	EPSD	ICGC;COSMIC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q9Y6K1	DNMT3A	P28482	MAPK1	T65	P58H	58	Missense	distal	-7	no	13.845	13.829	EPSD	ICGC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q9Y6K1	DNMT3A	P28482	MAPK1	S105	S105R	105	Missense	central	0	yes	14.989	0.000	EPSD	ICGC;COSMIC	8.102	Loss
CMGC_MAPK_ERK1_MAPK1_ST	Q9Y6K1	DNMT3A	P28482	MAPK1	S105	G109W	109	Missense	distal	4	no	14.989	14.732	EPSD	ICGC;COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q9Y6K1	DNMT3A	P28482	MAPK1	S105	E102K	102	Missense	distal	-3	no	14.989	14.911	EPSD	ICGC;COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q9Y6K1	DNMT3A	P28482	MAPK1	T138	A131E	131	Missense	distal	-7	no	12.941	12.949	EPSD	ICGC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q9Y6K1	DNMT3A	P28482	MAPK1	S255	D252A	252	Missense	distal	-3	no	17.002	16.764	PhosphoSitePlus	ICGC;COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q9Y6K1	DNMT3A	P28482	MAPK1	T261	D268G	268	Missense	distal	7	no	13.031	13.103	EPSD	ICGC;COSMIC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q9UBN7	HDAC6	P28482	MAPK1	S16	R12S	12	Missense	distal	-4	no	8.614	8.620	EPSD	ICGC;COSMIC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q9UBN7	HDAC6	P28482	MAPK1	S16	Q13H	13	Missense	distal	-3	no	8.614	8.561	EPSD	ICGC;COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q9UBN7	HDAC6	P28482	MAPK1	S22	V29A	29	Missense	distal	7	no	18.704	18.602	EPSD	ICGC;COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q9UBN7	HDAC6	P28482	MAPK1	T1041	P1046S	1046	Missense	distal	5	no	11.481	11.499	EPSD	ICGC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q9UBN7	HDAC6	P28482	MAPK1	T1041	P1046L	1046	Missense	distal	5	no	11.481	11.268	EPSD	ICGC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P33981	TTK	P28482	MAPK1	S80	D81Y	81	Missense	proximal	1	no	9.018	10.705	EPSD	ICGC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P33981	TTK	P28482	MAPK1	S80	N75S	75	Missense	distal	-5	no	9.018	9.066	EPSD	ICGC;COSMIC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P33981	TTK	P28482	MAPK1	S80	S76G	76	Missense	distal	-4	no	9.018	8.752	EPSD	ICGC;COSMIC;GDSC;CCLE	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P33981	TTK	P28482	MAPK1	S214	A211S	211	Missense	distal	-3	no	8.447	8.638	EPSD	ICGC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P33981	TTK	P28482	MAPK1	S214	A211D	211	Missense	distal	-3	no	8.447	8.686	EPSD	ICGC;COSMIC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P33981	TTK	P28482	MAPK1	S258	L259F	259	Missense	proximal	1	no	7.239	9.480	EPSD	ICGC;COSMIC	8.102	Gain
CMGC_MAPK_ERK1_MAPK1_ST	P33981	TTK	P28482	MAPK1	S281	D283N	283	Missense	proximal	2	no	15.075	15.015	EPSD	ICGC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P33981	TTK	P28482	MAPK1	S844	G838S	838	Missense	distal	-6	no	9.015	9.032	EPSD	ICGC;COSMIC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q86UR1	NOXA1	P28482	MAPK1	S282	P283Q	283	Missense	proximal	1	no	15.873	7.380	PhosphoSitePlus	ICGC;COSMIC	8.102	Loss
CMGC_MAPK_ERK1_MAPK1_ST	P47712	PLA2G4A	P28482	MAPK1	T41	D40G	40	Missense	proximal	-1	no	16.542	16.544	EPSD	ICGC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P47712	PLA2G4A	P28482	MAPK1	T41	A34S	34	Missense	distal	-7	no	16.542	16.541	EPSD	ICGC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P47712	PLA2G4A	P28482	MAPK1	T53	R57K	57	Missense	distal	4	no	15.064	15.074	EPSD	ICGC;COSMIC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P47712	PLA2G4A	P28482	MAPK1	S56	R57K	57	Missense	proximal	1	no	8.269	-0.596	EPSD	ICGC;COSMIC	8.102	Loss
CMGC_MAPK_ERK1_MAPK1_ST	P47712	PLA2G4A	P28482	MAPK1	T500	S501Y	501	Missense	proximal	1	no	6.174	8.561	EPSD	ICGC;COSMIC	8.102	Gain
CMGC_MAPK_ERK1_MAPK1_ST	P47712	PLA2G4A	P28482	MAPK1	S505	L498F	498	Missense	distal	-7	no	15.768	15.756	PhosphoSitePlus	ICGC;COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P47712	PLA2G4A	P28482	MAPK1	S505	S501Y	501	Missense	distal	-4	no	15.768	15.179	PhosphoSitePlus	ICGC;COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P47712	PLA2G4A	P28482	MAPK1	S505	L498V	498	Missense	distal	-7	no	15.768	15.761	PhosphoSitePlus	ICGC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P47712	PLA2G4A	P28482	MAPK1	S505	L507F	507	Missense	proximal	2	no	15.768	15.756	PhosphoSitePlus	ICGC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P47712	PLA2G4A	P28482	MAPK1	S508	S501Y	501	Missense	distal	-7	no	8.279	8.248	EPSD	ICGC;COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P47712	PLA2G4A	P28482	MAPK1	S508	L507F	507	Missense	proximal	-1	no	8.279	8.250	EPSD	ICGC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P47712	PLA2G4A	P28482	MAPK1	S508	D514Y	514	Missense	distal	6	no	8.279	7.706	EPSD	ICGC	8.102	Loss
CMGC_MAPK_ERK1_MAPK1_ST	P47712	PLA2G4A	P28482	MAPK1	S515	D517N	517	Missense	proximal	2	no	8.506	8.446	EPSD	ICGC;COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P47712	PLA2G4A	P28482	MAPK1	S515	D518N	518	Missense	distal	3	no	8.506	8.411	EPSD	ICGC;COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P47712	PLA2G4A	P28482	MAPK1	S515	D514Y	514	Missense	proximal	-1	no	8.506	8.487	EPSD	ICGC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q12931	TRAP1	P28482	MAPK1	T40	R47Q	47	Missense	distal	7	no	8.206	8.321	EPSD	ICGC;COSMIC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q12931	TRAP1	P28482	MAPK1	T40	T40I	40	Missense	central	0	yes	8.206	0.000	EPSD	ICGC	8.102	Loss
CMGC_MAPK_ERK1_MAPK1_ST	Q12931	TRAP1	P28482	MAPK1	S282	T275K	275	Missense	distal	-7	no	9.403	9.419	EPSD	ICGC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q12931	TRAP1	P28482	MAPK1	S511	K518T	518	Missense	distal	7	no	12.223	12.427	PhosphoSitePlus	ICGC;COSMIC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P19419	ELK1	P28482	MAPK1	T133	T133K	133	Missense	central	0	yes	14.506	0.000	EPSD	ICGC	8.102	Loss
CMGC_MAPK_ERK1_MAPK1_ST	P19419	ELK1	P28482	MAPK1	S304	G299S	299	Missense	distal	-5	no	13.262	13.268	EPSD	ICGC;COSMIC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P19419	ELK1	P28482	MAPK1	S304	A297G	297	Missense	distal	-7	no	13.262	13.246	EPSD	ICGC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P19419	ELK1	P28482	MAPK1	S324	S326I	326	Missense	proximal	2	no	16.645	16.502	EPSD	ICGC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P19419	ELK1	P28482	MAPK1	T353	P348S	348	Missense	distal	-5	no	12.838	12.912	EPSD	ICGC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P19419	ELK1	P28482	MAPK1	T363	T368K	368	Missense	distal	5	no	15.013	14.983	EPSD	ICGC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P19419	ELK1	P28482	MAPK1	T363	P364L	364	Missense	proximal	1	no	15.013	6.203	EPSD	ICGC;COSMIC	8.102	Loss
CMGC_MAPK_ERK1_MAPK1_ST	P19419	ELK1	P28482	MAPK1	T368	T368K	368	Missense	central	0	yes	15.156	0.000	EPSD	ICGC	8.102	Loss
CMGC_MAPK_ERK1_MAPK1_ST	P19419	ELK1	P28482	MAPK1	T368	P364L	364	Missense	distal	-4	no	15.156	14.851	EPSD	ICGC;COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P19419	ELK1	P28482	MAPK1	T368	S371L	371	Missense	distal	3	no	15.156	15.176	EPSD	ICGC;COSMIC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P19419	ELK1	P28482	MAPK1	S383	P390L	390	Missense	distal	7	no	13.857	14.156	PhosphoSitePlus	ICGC;COSMIC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P19419	ELK1	P28482	MAPK1	S383	S380R	380	Missense	distal	-3	no	13.857	14.014	PhosphoSitePlus	ICGC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P19419	ELK1	P28482	MAPK1	S383	H377N	377	Missense	distal	-6	no	13.857	13.909	PhosphoSitePlus	ICGC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P19419	ELK1	P28482	MAPK1	S383	R388H	388	Missense	distal	5	no	13.857	13.681	PhosphoSitePlus	ICGC;COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P19419	ELK1	P28482	MAPK1	S389	P390L	390	Missense	proximal	1	no	13.963	5.154	EPSD	ICGC;COSMIC	8.102	Loss
CMGC_MAPK_ERK1_MAPK1_ST	P19419	ELK1	P28482	MAPK1	S389	R388H	388	Missense	proximal	-1	no	13.963	13.940	EPSD	ICGC;COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q92908	GATA6	P28482	MAPK1	T34	P38T	38	Missense	distal	4	no	15.730	15.606	EPSD	ICGC;COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q92908	GATA6	P28482	MAPK1	T34	P38H	38	Missense	distal	4	no	15.730	15.555	EPSD	ICGC;COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q92908	GATA6	P28482	MAPK1	S37	P38T	38	Missense	proximal	1	no	17.103	8.605	EPSD	ICGC;COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q92908	GATA6	P28482	MAPK1	S37	P38H	38	Missense	proximal	1	no	17.103	9.280	EPSD	ICGC;COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q92908	GATA6	P28482	MAPK1	T62	A57T	57	Missense	distal	-5	no	9.735	9.713	EPSD	ICGC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q92908	GATA6	P28482	MAPK1	S266	A261E	261	Missense	distal	-5	no	16.370	16.271	PhosphoSitePlus	ICGC;COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q92908	GATA6	P28482	MAPK1	S266	A261V	261	Missense	distal	-5	no	16.370	16.342	PhosphoSitePlus	ICGC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q92908	GATA6	P28482	MAPK1	S266	A272S	272	Missense	distal	6	no	16.370	16.667	PhosphoSitePlus	ICGC;COSMIC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q92908	GATA6	P28482	MAPK1	S268	A261E	261	Missense	distal	-7	no	12.702	12.710	EPSD	ICGC;COSMIC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q92908	GATA6	P28482	MAPK1	S268	A261V	261	Missense	distal	-7	no	12.702	12.686	EPSD	ICGC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q92908	GATA6	P28482	MAPK1	S268	A272S	272	Missense	distal	4	no	12.702	12.796	EPSD	ICGC;COSMIC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q92908	GATA6	P28482	MAPK1	S377	G375D	375	Missense	proximal	-2	no	9.558	9.451	EPSD	ICGC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q92908	GATA6	P28482	MAPK1	S436	R438W	438	Missense	proximal	2	no	8.986	8.617	EPSD	ICGC;COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q92908	GATA6	P28482	MAPK1	S437	R438W	438	Missense	proximal	1	no	6.145	8.423	EPSD	ICGC;COSMIC	8.102	Gain
CMGC_MAPK_ERK1_MAPK1_ST	Q92908	GATA6	P28482	MAPK1	T515	I512T	512	Missense	distal	-3	no	15.246	15.478	EPSD	ICGC;COSMIC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q92908	GATA6	P28482	MAPK1	T515	M514I	514	Missense	proximal	-1	no	15.246	15.230	EPSD	ICGC;COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q92908	GATA6	P28482	MAPK1	T515	T517A	517	Missense	proximal	2	no	15.246	15.167	EPSD	ICGC;COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q92908	GATA6	P28482	MAPK1	S531	D525N	525	Missense	distal	-6	no	13.901	13.855	EPSD	ICGC;COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q92908	GATA6	P28482	MAPK1	T534	A541S	541	Missense	distal	7	no	9.999	9.817	EPSD	ICGC;COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P04637	TP53	P28482	MAPK1	S15	E11K	11	Missense	distal	-4	no	12.725	12.743	PhosphoSitePlus;EPSD	ICGC;COSMIC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P04637	TP53	P28482	MAPK1	T18	E11K	11	Missense	distal	-7	no	9.122	9.116	EPSD	ICGC;COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P04637	TP53	P28482	MAPK1	T18	W23C	23	Missense	distal	5	no	9.122	9.219	EPSD	ICGC;COSMIC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P04637	TP53	P28482	MAPK1	S33	P34L	34	Missense	proximal	1	no	13.820	5.010	EPSD	ICGC;COSMIC	8.102	Loss
CMGC_MAPK_ERK1_MAPK1_ST	P04637	TP53	P28482	MAPK1	S33	S33F	33	Missense	central	0	yes	13.820	0.000	EPSD	ICGC;COSMIC	8.102	Loss
CMGC_MAPK_ERK1_MAPK1_ST	P04637	TP53	P28482	MAPK1	S33	N30I	30	Missense	distal	-3	no	13.820	13.540	EPSD	ICGC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P04637	TP53	P28482	MAPK1	S46	D48G	48	Missense	proximal	2	no	11.716	11.750	EPSD	ICGC;COSMIC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P04637	TP53	P28482	MAPK1	S46	Q52K	52	Missense	distal	6	no	11.716	12.060	EPSD	ICGC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P04637	TP53	P28482	MAPK1	T81	A88D	88	Missense	distal	7	no	14.705	14.520	EPSD	ICGC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P04637	TP53	P28482	MAPK1	T81	P87Q	87	Missense	distal	6	no	14.705	14.418	EPSD	ICGC;COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P04637	TP53	P28482	MAPK1	S127	T125R	125	Missense	proximal	-2	no	14.148	15.029	EPSD	ICGC;COSMIC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P04637	TP53	P28482	MAPK1	S127	F134C	134	Missense	distal	7	no	14.148	14.459	EPSD	ICGC;COSMIC;CCLE	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P04637	TP53	P28482	MAPK1	S127	C124G	124	Missense	distal	-3	no	14.148	14.663	EPSD	ICGC;COSMIC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P04637	TP53	P28482	MAPK1	S127	C124R	124	Missense	distal	-3	no	14.148	14.832	EPSD	ICGC;COSMIC;GDSC;CCLE	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P04637	TP53	P28482	MAPK1	S127	L130H	130	Missense	distal	3	no	14.148	14.147	EPSD	ICGC;COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P04637	TP53	P28482	MAPK1	S127	T125A	125	Missense	proximal	-2	no	14.148	13.700	EPSD	ICGC;COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P04637	TP53	P28482	MAPK1	S127	N131Y	131	Missense	distal	4	no	14.148	13.991	EPSD	ICGC;COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P04637	TP53	P28482	MAPK1	S127	K120M	120	Missense	distal	-7	no	14.148	14.128	EPSD	ICGC;COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P04637	TP53	P28482	MAPK1	S127	K132M	132	Missense	distal	5	no	14.148	14.047	EPSD	ICGC;COSMIC;CCLE	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P04637	TP53	P28482	MAPK1	S127	M133T	133	Missense	distal	6	no	14.148	14.371	EPSD	ICGC;COSMIC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P04637	TP53	P28482	MAPK1	S127	K120R	120	Missense	distal	-7	no	14.148	14.145	EPSD	ICGC;COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P04637	TP53	P28482	MAPK1	S127	C124Y	124	Missense	distal	-3	no	14.148	14.405	EPSD	ICGC;COSMIC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P04637	TP53	P28482	MAPK1	T150	R156L	156	Missense	distal	6	no	11.263	10.964	EPSD	ICGC;COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P04637	TP53	P28482	MAPK1	T150	L145Q	145	Missense	distal	-5	no	11.263	11.239	EPSD	ICGC;COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P04637	TP53	P28482	MAPK1	T150	P152R	152	Missense	proximal	2	no	11.263	11.377	EPSD	ICGC;COSMIC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P04637	TP53	P28482	MAPK1	T150	G154S	154	Missense	distal	4	no	11.263	11.312	EPSD	ICGC;COSMIC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P04637	TP53	P28482	MAPK1	T150	V157A	157	Missense	distal	7	no	11.263	11.162	EPSD	ICGC;COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P04637	TP53	P28482	MAPK1	T150	P151F	151	Missense	proximal	1	no	11.263	4.694	EPSD	ICGC;COSMIC	8.102	Loss
CMGC_MAPK_ERK1_MAPK1_ST	P04637	TP53	P28482	MAPK1	T150	V147G	147	Missense	distal	-3	no	11.263	11.382	EPSD	ICGC;COSMIC;GDSC;CCLE	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P04637	TP53	P28482	MAPK1	S315	T312I	312	Missense	distal	-3	no	13.607	13.375	EPSD	ICGC;COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P04637	TP53	P28482	MAPK1	S315	P322T	322	Missense	distal	7	no	13.607	13.770	EPSD	ICGC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P04637	TP53	P28482	MAPK1	S376	T377P	377	Missense	proximal	1	no	8.969	17.468	EPSD	ICGC;COSMIC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P04637	TP53	P28482	MAPK1	S376	G374C	374	Missense	proximal	-2	no	8.969	8.397	EPSD	ICGC;COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P04637	TP53	P28482	MAPK1	S376	R379S	379	Missense	distal	3	no	8.969	8.992	EPSD	ICGC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P04637	TP53	P28482	MAPK1	S376	R379C	379	Missense	distal	3	no	8.969	9.096	EPSD	ICGC;COSMIC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P04637	TP53	P28482	MAPK1	T387	F385L	385	Missense	proximal	-2	no	7.379	8.103	EPSD	ICGC;COSMIC	8.102	Gain
CMGC_MAPK_ERK1_MAPK1_ST	P04637	TP53	P28482	MAPK1	S392	F385L	385	Missense	distal	-7	no	8.624	8.636	EPSD	ICGC;COSMIC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q14686	NCOA6	P28482	MAPK1	T416	S412C	412	Missense	distal	-4	no	14.203	13.559	EPSD	ICGC;COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q14686	NCOA6	P28482	MAPK1	T416	S412T	412	Missense	distal	-4	no	14.203	13.973	EPSD	ICGC;COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q14686	NCOA6	P28482	MAPK1	S667	S673L	673	Missense	distal	6	no	9.041	8.634	EPSD	ICGC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q14686	NCOA6	P28482	MAPK1	S673	M677V	677	Missense	distal	4	no	13.034	13.123	EPSD	ICGC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q14686	NCOA6	P28482	MAPK1	S673	S673L	673	Missense	central	0	yes	13.034	0.000	EPSD	ICGC	8.102	Loss
CMGC_MAPK_ERK1_MAPK1_ST	Q14686	NCOA6	P28482	MAPK1	T678	M677V	677	Missense	proximal	-1	no	15.371	15.396	EPSD	ICGC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q14686	NCOA6	P28482	MAPK1	T678	S673L	673	Missense	distal	-5	no	15.371	15.446	EPSD	ICGC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q14686	NCOA6	P28482	MAPK1	T678	K681N	681	Missense	distal	3	no	15.371	15.365	EPSD	ICGC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q14686	NCOA6	P28482	MAPK1	S884	L882I	882	Missense	proximal	-2	no	14.794	14.817	PhosphoSitePlus	ICGC;COSMIC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q14686	NCOA6	P28482	MAPK1	S884	T883K	883	Missense	proximal	-1	no	14.794	14.849	PhosphoSitePlus	ICGC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q14686	NCOA6	P28482	MAPK1	T932	R936C	936	Missense	distal	4	no	14.252	13.993	EPSD	ICGC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q14686	NCOA6	P28482	MAPK1	T932	T932P	932	Missense	central	0	yes	14.252	0.000	EPSD	ICGC;COSMIC	8.102	Loss
CMGC_MAPK_ERK1_MAPK1_ST	Q14686	NCOA6	P28482	MAPK1	S1091	P1085H	1085	Missense	distal	-6	no	16.186	16.111	EPSD	ICGC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q14686	NCOA6	P28482	MAPK1	T1211	P1217T	1217	Missense	distal	6	no	15.809	15.599	EPSD	ICGC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q14686	NCOA6	P28482	MAPK1	S1216	P1217T	1217	Missense	proximal	1	no	14.689	6.190	EPSD	ICGC	8.102	Loss
CMGC_MAPK_ERK1_MAPK1_ST	Q14686	NCOA6	P28482	MAPK1	T1224	R1228H	1228	Missense	distal	4	no	16.939	16.797	EPSD	ICGC;COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q14686	NCOA6	P28482	MAPK1	T1224	R1228S	1228	Missense	distal	4	no	16.939	16.962	EPSD	ICGC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q14686	NCOA6	P28482	MAPK1	T1224	P1217T	1217	Missense	distal	-7	no	16.939	16.922	EPSD	ICGC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q14686	NCOA6	P28482	MAPK1	S1240	E1233D	1233	Missense	distal	-7	no	15.213	15.205	EPSD	ICGC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q14686	NCOA6	P28482	MAPK1	S1325	R1331T	1331	Missense	distal	6	no	14.502	14.399	EPSD	ICGC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q14686	NCOA6	P28482	MAPK1	S1325	R1331G	1331	Missense	distal	6	no	14.502	14.532	EPSD	ICGC;COSMIC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q14686	NCOA6	P28482	MAPK1	S1325	T1321K	1321	Missense	distal	-4	no	14.502	14.805	EPSD	ICGC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q14686	NCOA6	P28482	MAPK1	S1325	A1320E	1320	Missense	distal	-5	no	14.502	14.402	EPSD	ICGC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q14686	NCOA6	P28482	MAPK1	S1325	R1323W	1323	Missense	proximal	-2	no	14.502	13.579	EPSD	ICGC;COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q14686	NCOA6	P28482	MAPK1	T1341	P1344T	1344	Missense	distal	3	no	14.975	15.036	EPSD	ICGC;COSMIC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q14686	NCOA6	P28482	MAPK1	T1341	S1336Y	1336	Missense	distal	-5	no	14.975	15.106	EPSD	ICGC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q14686	NCOA6	P28482	MAPK1	S1343	P1344T	1344	Missense	proximal	1	no	14.459	5.960	EPSD	ICGC;COSMIC	8.102	Loss
CMGC_MAPK_ERK1_MAPK1_ST	Q14686	NCOA6	P28482	MAPK1	S1343	S1336Y	1336	Missense	distal	-7	no	14.459	14.427	EPSD	ICGC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q14686	NCOA6	P28482	MAPK1	S1377	P1371L	1371	Missense	distal	-6	no	12.040	11.948	EPSD	ICGC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q14686	NCOA6	P28482	MAPK1	S1377	R1372T	1372	Missense	distal	-5	no	12.040	12.095	EPSD	ICGC;COSMIC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q14686	NCOA6	P28482	MAPK1	T1379	R1372T	1372	Missense	distal	-7	no	12.352	12.341	EPSD	ICGC;COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q14686	NCOA6	P28482	MAPK1	S1481	S1481Y	1481	Missense	central	0	yes	15.799	0.000	EPSD	ICGC;COSMIC	8.102	Loss
CMGC_MAPK_ERK1_MAPK1_ST	Q14686	NCOA6	P28482	MAPK1	T1516	L1510I	1510	Missense	distal	-6	no	12.348	12.313	EPSD	ICGC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q14686	NCOA6	P28482	MAPK1	S1721	P1724A	1724	Missense	distal	3	no	12.747	12.825	EPSD	ICGC;COSMIC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q14686	NCOA6	P28482	MAPK1	T1739	P1746S	1746	Missense	distal	7	no	14.570	14.581	EPSD	ICGC;COSMIC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q14686	NCOA6	P28482	MAPK1	S1745	P1746S	1746	Missense	proximal	1	no	14.267	4.872	EPSD	ICGC;COSMIC	8.102	Loss
CMGC_MAPK_ERK1_MAPK1_ST	Q14686	NCOA6	P28482	MAPK1	S1745	S1751Y	1751	Missense	distal	6	no	14.267	13.648	EPSD	ICGC;COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q14686	NCOA6	P28482	MAPK1	S1751	P1746S	1746	Missense	distal	-5	no	13.564	13.638	EPSD	ICGC;COSMIC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q14686	NCOA6	P28482	MAPK1	S1751	S1751Y	1751	Missense	central	0	yes	13.564	0.000	EPSD	ICGC;COSMIC	8.102	Loss
CMGC_MAPK_ERK1_MAPK1_ST	Q14686	NCOA6	P28482	MAPK1	S1756	Q1761K	1761	Missense	distal	5	no	8.234	8.269	EPSD	ICGC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q14686	NCOA6	P28482	MAPK1	S1756	S1751Y	1751	Missense	distal	-5	no	8.234	8.366	EPSD	ICGC;COSMIC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q14686	NCOA6	P28482	MAPK1	S1794	P1795L	1795	Missense	proximal	1	no	12.374	3.564	EPSD	ICGC;COSMIC	8.102	Loss
CMGC_MAPK_ERK1_MAPK1_ST	Q14686	NCOA6	P28482	MAPK1	S1794	T1790A	1790	Missense	distal	-4	no	12.374	12.394	EPSD	ICGC;COSMIC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q14686	NCOA6	P28482	MAPK1	S1794	L1796I	1796	Missense	proximal	2	no	12.374	12.351	EPSD	ICGC;COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q14686	NCOA6	P28482	MAPK1	S1794	T1791K	1791	Missense	distal	-3	no	12.374	12.326	EPSD	ICGC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q14686	NCOA6	P28482	MAPK1	S1794	L1796F	1796	Missense	proximal	2	no	12.374	12.362	EPSD	ICGC;COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q14686	NCOA6	P28482	MAPK1	S1794	N1799S	1799	Missense	distal	5	no	12.374	12.447	EPSD	ICGC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q14686	NCOA6	P28482	MAPK1	S1800	P1795L	1795	Missense	distal	-5	no	12.806	12.955	EPSD	ICGC;COSMIC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q14686	NCOA6	P28482	MAPK1	S1800	L1796I	1796	Missense	distal	-4	no	12.806	12.439	EPSD	ICGC;COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q14686	NCOA6	P28482	MAPK1	S1800	L1796F	1796	Missense	distal	-4	no	12.806	12.765	EPSD	ICGC;COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q14686	NCOA6	P28482	MAPK1	S1800	S1803Y	1803	Missense	distal	3	no	12.806	12.864	EPSD	ICGC;COSMIC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q14686	NCOA6	P28482	MAPK1	S1800	N1799S	1799	Missense	proximal	-1	no	12.806	12.757	EPSD	ICGC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q14686	NCOA6	P28482	MAPK1	S1809	S1803Y	1803	Missense	distal	-6	no	14.569	14.455	EPSD	ICGC;COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q14686	NCOA6	P28482	MAPK1	T1878	T1885S	1885	Missense	distal	7	no	13.582	13.430	EPSD	ICGC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q14686	NCOA6	P28482	MAPK1	T1878	T1880K	1880	Missense	proximal	2	no	13.582	13.565	EPSD	ICGC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q14686	NCOA6	P28482	MAPK1	T1878	S1871Y	1871	Missense	distal	-7	no	13.582	13.551	EPSD	ICGC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q14686	NCOA6	P28482	MAPK1	T1880	T1885S	1885	Missense	distal	5	no	12.985	13.059	EPSD	ICGC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q14686	NCOA6	P28482	MAPK1	T1880	T1880K	1880	Missense	central	0	yes	12.985	0.000	EPSD	ICGC	8.102	Loss
CMGC_MAPK_ERK1_MAPK1_ST	Q14686	NCOA6	P28482	MAPK1	S1892	T1890P	1890	Missense	proximal	-2	no	14.453	17.152	EPSD	ICGC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q14686	NCOA6	P28482	MAPK1	S1892	P1896L	1896	Missense	distal	4	no	14.453	14.332	EPSD	ICGC;COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q14686	NCOA6	P28482	MAPK1	S1892	T1885S	1885	Missense	distal	-7	no	14.453	14.466	EPSD	ICGC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q14686	NCOA6	P28482	MAPK1	T1898	P1896L	1896	Missense	proximal	-2	no	9.197	7.280	EPSD	ICGC;COSMIC	8.102	Loss
CMGC_MAPK_ERK1_MAPK1_ST	Q14686	NCOA6	P28482	MAPK1	S2053	A2054V	2054	Missense	proximal	1	no	9.859	7.949	EPSD	ICGC;COSMIC	8.102	Loss
CMGC_MAPK_ERK1_MAPK1_ST	Q9UQC2	GAB2	P28482	MAPK1	T319	P320S	320	Missense	proximal	1	no	16.038	6.643	EPSD	ICGC;COSMIC	8.102	Loss
CMGC_MAPK_ERK1_MAPK1_ST	Q9UQC2	GAB2	P28482	MAPK1	S322	P320S	320	Missense	proximal	-2	no	11.436	8.602	EPSD	ICGC;COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P10828	THRB	P28482	MAPK1	T2	T2P	2	Missense	central	0	yes	12.046	0.000	EPSD	ICGC;COSMIC	8.102	Loss
CMGC_MAPK_ERK1_MAPK1_ST	P10828	THRB	P28482	MAPK1	S55	Q53K	53	Missense	proximal	-2	no	14.655	15.229	EPSD	ICGC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P10828	THRB	P28482	MAPK1	S55	H57N	57	Missense	proximal	2	no	14.655	14.709	EPSD	ICGC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P10828	THRB	P28482	MAPK1	S55	T48K	48	Missense	distal	-7	no	14.655	14.670	EPSD	ICGC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P10828	THRB	P28482	MAPK1	S55	T61N	61	Missense	distal	6	no	14.655	14.769	EPSD	ICGC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P10828	THRB	P28482	MAPK1	S55	E52K	52	Missense	distal	-3	no	14.655	14.577	EPSD	ICGC;COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P10828	THRB	P28482	MAPK1	S55	T48M	48	Missense	distal	-7	no	14.655	14.651	EPSD	ICGC;COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P10828	THRB	P28482	MAPK1	S142	P141A	141	Missense	proximal	-1	no	8.459	8.422	PhosphoSitePlus	ICGC;COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P10828	THRB	P28482	MAPK1	S142	Y143C	143	Missense	proximal	1	no	8.459	2.020	PhosphoSitePlus	ICGC;COSMIC	8.102	Loss
CMGC_MAPK_ERK1_MAPK1_ST	P14921	ETS1	P28482	MAPK1	S26	P25L	25	Missense	proximal	-1	no	15.770	15.711	EPSD	ICGC;COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P14921	ETS1	P28482	MAPK1	S26	E22D	22	Missense	distal	-4	no	15.770	15.785	EPSD	ICGC;COSMIC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P14921	ETS1	P28482	MAPK1	S26	D28N	28	Missense	proximal	2	no	15.770	15.710	EPSD	ICGC;COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P14921	ETS1	P28482	MAPK1	S26	D20N	20	Missense	distal	-6	no	15.770	15.725	EPSD	ICGC;COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P14921	ETS1	P28482	MAPK1	S282	P281Q	281	Missense	proximal	-1	no	8.112	8.071	EPSD	ICGC	8.102	Loss
CMGC_MAPK_ERK1_MAPK1_ST	P14921	ETS1	P28482	MAPK1	S285	P281Q	281	Missense	distal	-4	no	8.754	8.561	EPSD	ICGC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q9NRF2	SH2B1	P28482	MAPK1	S25	R27W	27	Missense	proximal	2	no	13.882	13.513	EPSD	ICGC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q9NRF2	SH2B1	P28482	MAPK1	S25	P22L	22	Missense	distal	-3	no	13.882	13.498	EPSD	ICGC;COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q9NRF2	SH2B1	P28482	MAPK1	S88	S88L	88	Missense	central	0	yes	13.850	0.000	EPSD	ICGC	8.102	Loss
CMGC_MAPK_ERK1_MAPK1_ST	Q9NRF2	SH2B1	P28482	MAPK1	S88	P89A	89	Missense	proximal	1	no	13.850	6.220	EPSD	ICGC;COSMIC	8.102	Loss
CMGC_MAPK_ERK1_MAPK1_ST	Q9NRF2	SH2B1	P28482	MAPK1	S88	R82L	82	Missense	distal	-6	no	13.850	13.750	EPSD	ICGC;COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q9NRF2	SH2B1	P28482	MAPK1	S96	P89A	89	Missense	distal	-7	no	15.960	15.958	PhosphoSitePlus	ICGC;COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q9NRF2	SH2B1	P28482	MAPK1	S96	A99G	99	Missense	distal	3	no	15.960	15.966	PhosphoSitePlus	ICGC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q9NRF2	SH2B1	P28482	MAPK1	S102	A99G	99	Missense	distal	-3	no	13.059	13.238	EPSD	ICGC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q9NRF2	SH2B1	P28482	MAPK1	S219	S215G	215	Missense	distal	-4	no	12.112	11.846	EPSD	ICGC;COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q9NRF2	SH2B1	P28482	MAPK1	S324	T331I	331	Missense	distal	7	no	7.920	8.316	EPSD	ICGC;COSMIC	8.102	Gain
CMGC_MAPK_ERK1_MAPK1_ST	Q9NRF2	SH2B1	P28482	MAPK1	S376	A382S	382	Missense	distal	6	no	10.657	10.954	EPSD	ICGC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q9NRF2	SH2B1	P28482	MAPK1	S384	A382S	382	Missense	proximal	-2	no	12.580	12.892	EPSD	ICGC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P53355	DAPK1	P28482	MAPK1	T180	E187K	187	Missense	distal	7	no	11.610	11.617	EPSD	ICGC;COSMIC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P53355	DAPK1	P28482	MAPK1	T180	F183C	183	Missense	distal	3	no	11.610	11.651	EPSD	ICGC;COSMIC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P53355	DAPK1	P28482	MAPK1	S321	S321L	321	Missense	central	0	yes	8.189	0.000	EPSD	ICGC;COSMIC	8.102	Loss
CMGC_MAPK_ERK1_MAPK1_ST	P53355	DAPK1	P28482	MAPK1	S321	R317G	317	Missense	distal	-4	no	8.189	7.929	EPSD	ICGC;COSMIC	8.102	Loss
CMGC_MAPK_ERK1_MAPK1_ST	P53355	DAPK1	P28482	MAPK1	S333	D338N	338	Missense	distal	5	no	8.356	8.258	EPSD	ICGC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P53355	DAPK1	P28482	MAPK1	S333	S333R	333	Missense	central	0	yes	8.356	0.000	EPSD	ICGC	8.102	Loss
CMGC_MAPK_ERK1_MAPK1_ST	P53355	DAPK1	P28482	MAPK1	S342	S342F	342	Missense	central	0	yes	9.126	0.000	EPSD	ICGC;COSMIC	8.102	Loss
CMGC_MAPK_ERK1_MAPK1_ST	P53355	DAPK1	P28482	MAPK1	S342	V344L	344	Missense	proximal	2	no	9.126	9.032	EPSD	ICGC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P53355	DAPK1	P28482	MAPK1	S342	I348V	348	Missense	distal	6	no	9.126	9.578	EPSD	ICGC;COSMIC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P53355	DAPK1	P28482	MAPK1	S342	K346N	346	Missense	distal	4	no	9.126	9.101	EPSD	ICGC;COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P53355	DAPK1	P28482	MAPK1	S342	D338N	338	Missense	distal	-4	no	9.126	9.098	EPSD	ICGC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P53355	DAPK1	P28482	MAPK1	S342	A347V	347	Missense	distal	5	no	9.126	9.143	EPSD	ICGC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P53355	DAPK1	P28482	MAPK1	T612	L616P	616	Missense	distal	4	no	13.055	13.176	EPSD	ICGC;COSMIC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P53355	DAPK1	P28482	MAPK1	T612	N619Y	619	Missense	distal	7	no	13.055	13.590	EPSD	ICGC;COSMIC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P53355	DAPK1	P28482	MAPK1	T612	R611L	611	Missense	proximal	-1	no	13.055	13.015	EPSD	ICGC;COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P53355	DAPK1	P28482	MAPK1	T612	T612M	612	Missense	central	0	yes	13.055	0.000	EPSD	ICGC;COSMIC	8.102	Loss
CMGC_MAPK_ERK1_MAPK1_ST	P53355	DAPK1	P28482	MAPK1	S734	L736M	736	Missense	proximal	2	no	19.425	19.381	PhosphoSitePlus	ICGC;COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P53355	DAPK1	P28482	MAPK1	S734	S738F	738	Missense	distal	4	no	19.425	19.247	PhosphoSitePlus	ICGC;GDSC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P53355	DAPK1	P28482	MAPK1	T1053	R1055L	1055	Missense	proximal	2	no	13.831	13.570	EPSD	ICGC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P53355	DAPK1	P28482	MAPK1	T1053	G1046W	1046	Missense	distal	-7	no	13.831	13.794	EPSD	ICGC;COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P53355	DAPK1	P28482	MAPK1	T1053	R1055Q	1055	Missense	proximal	2	no	13.831	13.540	EPSD	ICGC;COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P41182	BCL6	P28482	MAPK1	S3	D6E	6	Missense	distal	3	no	11.451	11.355	EPSD	ICGC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P41182	BCL6	P28482	MAPK1	S250	H255Q	255	Missense	distal	5	no	15.929	15.936	EPSD	ICGC;COSMIC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P41182	BCL6	P28482	MAPK1	S250	S250F	250	Missense	central	0	yes	15.929	0.000	EPSD	ICGC	8.102	Loss
CMGC_MAPK_ERK1_MAPK1_ST	P41182	BCL6	P28482	MAPK1	S260	T264K	264	Missense	distal	4	no	15.090	15.190	EPSD	ICGC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P41182	BCL6	P28482	MAPK1	S330	R325W	325	Missense	distal	-5	no	14.464	14.740	EPSD	ICGC;COSMIC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P41182	BCL6	P28482	MAPK1	S330	Q332K	332	Missense	proximal	2	no	14.464	14.575	EPSD	ICGC;COSMIC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P41182	BCL6	P28482	MAPK1	S333	Q332K	332	Missense	proximal	-1	no	17.066	17.120	PhosphoSitePlus;EPSD	ICGC;COSMIC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P41182	BCL6	P28482	MAPK1	S333	D338E	338	Missense	distal	5	no	17.066	16.997	PhosphoSitePlus;EPSD	ICGC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P41182	BCL6	P28482	MAPK1	S343	D338E	338	Missense	distal	-5	no	17.275	17.230	EPSD;PhosphoSitePlus	ICGC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P41182	BCL6	P28482	MAPK1	S366	A372T	372	Missense	distal	6	no	13.294	13.380	EPSD	ICGC;COSMIC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P41182	BCL6	P28482	MAPK1	S427	E421K	421	Missense	distal	-6	no	13.658	13.632	EPSD	ICGC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P41182	BCL6	P28482	MAPK1	S457	M454I	454	Missense	distal	-3	no	13.867	13.863	EPSD	ICGC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P41182	BCL6	P28482	MAPK1	S457	P458H	458	Missense	proximal	1	no	13.867	6.043	EPSD	ICGC	8.102	Loss
CMGC_MAPK_ERK1_MAPK1_ST	P41182	BCL6	P28482	MAPK1	S457	R459C	459	Missense	proximal	2	no	13.867	13.494	EPSD	ICGC;COSMIC;GDSC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P41182	BCL6	P28482	MAPK1	S466	R459C	459	Missense	distal	-7	no	11.972	11.940	EPSD	ICGC;COSMIC;GDSC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P41182	BCL6	P28482	MAPK1	S466	P473L	473	Missense	distal	7	no	11.972	12.271	EPSD	ICGC;COSMIC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q13164	MAPK7	P28482	MAPK1	T209	S210P	210	Missense	proximal	1	no	7.098	16.493	EPSD	ICGC	8.102	Gain
CMGC_MAPK_ERK1_MAPK1_ST	Q13164	MAPK7	P28482	MAPK1	S210	S210P	210	Missense	central	0	yes	10.837	0.000	EPSD	ICGC	8.102	Loss
CMGC_MAPK_ERK1_MAPK1_ST	Q13164	MAPK7	P28482	MAPK1	S210	A212T	212	Missense	proximal	2	no	10.837	10.916	EPSD	ICGC;COSMIC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q13164	MAPK7	P28482	MAPK1	T594	P589S	589	Missense	distal	-5	no	14.134	14.208	EPSD	ICGC;COSMIC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q13164	MAPK7	P28482	MAPK1	T594	P595S	595	Missense	proximal	1	no	14.134	4.739	EPSD	ICGC;COSMIC	8.102	Loss
CMGC_MAPK_ERK1_MAPK1_ST	Q13164	MAPK7	P28482	MAPK1	T733	A739S	739	Missense	distal	6	no	12.957	13.253	PhosphoSitePlus	ICGC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q13164	MAPK7	P28482	MAPK1	S774	A771S	771	Missense	distal	-3	no	8.011	8.202	EPSD	ICGC	8.102	Gain
CMGC_MAPK_ERK1_MAPK1_ST	Q13164	MAPK7	P28482	MAPK1	S803	S803Y	803	Missense	central	0	yes	16.120	0.000	EPSD	ICGC;COSMIC	8.102	Loss
CMGC_MAPK_ERK1_MAPK1_ST	Q9H9Z2	LIN28A	P28482	MAPK1	T189	P182L	182	Missense	distal	-7	no	12.220	12.208	EPSD	ICGC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q9H9Z2	LIN28A	P28482	MAPK1	T189	F191Y	191	Missense	proximal	2	no	12.220	12.184	EPSD	ICGC;COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q9H9Z2	LIN28A	P28482	MAPK1	T189	P182H	182	Missense	distal	-7	no	12.220	12.204	EPSD	ICGC;COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q9H9Z2	LIN28A	P28482	MAPK1	S200	H199N	199	Missense	proximal	-1	no	16.120	16.168	PhosphoSitePlus	ICGC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q12772	SREBF2	P28482	MAPK1	S101	S103L	103	Missense	proximal	2	no	13.077	12.957	EPSD	ICGC;COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q12772	SREBF2	P28482	MAPK1	S106	S103L	103	Missense	distal	-3	no	13.276	13.068	EPSD	ICGC;COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q12772	SREBF2	P28482	MAPK1	T124	L131I	131	Missense	distal	7	no	15.491	15.751	EPSD	ICGC;COSMIC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q12772	SREBF2	P28482	MAPK1	T128	L131I	131	Missense	distal	3	no	13.670	13.708	EPSD	ICGC;COSMIC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q12772	SREBF2	P28482	MAPK1	S455	G454R	454	Missense	proximal	-1	no	18.586	18.621	PhosphoSitePlus;EPSD	ICGC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q12772	SREBF2	P28482	MAPK1	S469	P471L	471	Missense	proximal	2	no	17.557	17.410	EPSD	ICGC;COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q12772	SREBF2	P28482	MAPK1	S469	V472L	472	Missense	distal	3	no	17.557	17.590	EPSD	ICGC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q12772	SREBF2	P28482	MAPK1	S846	S846C	846	Missense	central	0	yes	9.487	0.000	EPSD	ICGC;COSMIC	8.102	Loss
CMGC_MAPK_ERK1_MAPK1_ST	Q12772	SREBF2	P28482	MAPK1	S846	D849N	849	Missense	distal	3	no	9.487	9.391	EPSD	ICGC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q12772	SREBF2	P28482	MAPK1	S846	V851M	851	Missense	distal	5	no	9.487	9.425	EPSD	ICGC;COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q12772	SREBF2	P28482	MAPK1	S846	H845R	845	Missense	proximal	-1	no	9.487	9.510	EPSD	ICGC;COSMIC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q12772	SREBF2	P28482	MAPK1	S855	R860S	860	Missense	distal	5	no	14.412	14.380	EPSD	ICGC;COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q12772	SREBF2	P28482	MAPK1	S855	D849N	849	Missense	distal	-6	no	14.412	14.366	EPSD	ICGC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q12772	SREBF2	P28482	MAPK1	S855	V851M	851	Missense	distal	-4	no	14.412	14.300	EPSD	ICGC;COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q12772	SREBF2	P28482	MAPK1	S855	M854L	854	Missense	proximal	-1	no	14.412	14.402	EPSD	ICGC;CCLE	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q12772	SREBF2	P28482	MAPK1	S855	S859F	859	Missense	distal	4	no	14.412	14.234	EPSD	ICGC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q12772	SREBF2	P28482	MAPK1	S859	R860S	860	Missense	proximal	1	no	8.112	8.372	EPSD	ICGC;COSMIC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q12772	SREBF2	P28482	MAPK1	S859	M854L	854	Missense	distal	-5	no	8.112	8.109	EPSD	ICGC;CCLE	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q12772	SREBF2	P28482	MAPK1	S859	S859F	859	Missense	central	0	yes	8.112	0.000	EPSD	ICGC	8.102	Loss
CMGC_MAPK_ERK1_MAPK1_ST	Q12772	SREBF2	P28482	MAPK1	S914	S914G	914	Missense	central	0	yes	11.735	0.000	EPSD	ICGC;COSMIC	8.102	Loss
CMGC_MAPK_ERK1_MAPK1_ST	Q12772	SREBF2	P28482	MAPK1	S1046	R1040C	1040	Missense	distal	-6	no	13.616	13.441	EPSD	ICGC;COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q12772	SREBF2	P28482	MAPK1	S1046	H1051L	1051	Missense	distal	5	no	13.616	13.529	EPSD	ICGC;COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P06401	PGR	P28482	MAPK1	S20	G17S	17	Missense	distal	-3	no	16.972	16.984	EPSD	ICGC;COSMIC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P06401	PGR	P28482	MAPK1	S20	V14M	14	Missense	distal	-6	no	16.972	16.974	EPSD	ICGC;COSMIC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P06401	PGR	P28482	MAPK1	S130	Q126K	126	Missense	distal	-4	no	13.049	13.231	EPSD	ICGC;COSMIC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P06401	PGR	P28482	MAPK1	S162	S168Y	168	Missense	distal	6	no	18.703	18.084	EPSD	ICGC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P06401	PGR	P28482	MAPK1	S162	L164I	164	Missense	proximal	2	no	18.703	18.679	EPSD	ICGC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P06401	PGR	P28482	MAPK1	S190	L189M	189	Missense	proximal	-1	no	13.636	13.646	EPSD	ICGC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P06401	PGR	P28482	MAPK1	S190	R193Q	193	Missense	distal	3	no	13.636	13.658	EPSD	ICGC;COSMIC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P06401	PGR	P28482	MAPK1	S213	A208T	208	Missense	distal	-5	no	15.143	15.121	EPSD	ICGC;COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P06401	PGR	P28482	MAPK1	S213	G207R	207	Missense	distal	-6	no	15.143	15.194	EPSD	ICGC;GDSC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P06401	PGR	P28482	MAPK1	S294	T299M	299	Missense	distal	5	no	14.860	14.729	PhosphoSitePlus	ICGC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P06401	PGR	P28482	MAPK1	S294	P291L	291	Missense	distal	-3	no	14.860	14.476	PhosphoSitePlus	ICGC;COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P06401	PGR	P28482	MAPK1	S294	A287T	287	Missense	distal	-7	no	14.860	14.845	PhosphoSitePlus	ICGC;GDSC;CCLE	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P06401	PGR	P28482	MAPK1	S344	R343W	343	Missense	proximal	-1	no	9.114	9.013	EPSD	ICGC;COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P06401	PGR	P28482	MAPK1	S344	P341L	341	Missense	distal	-3	no	9.114	8.730	EPSD	ICGC;COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P06401	PGR	P28482	MAPK1	S344	P341T	341	Missense	distal	-3	no	9.114	8.905	EPSD	ICGC;COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P06401	PGR	P28482	MAPK1	S345	R343W	343	Missense	proximal	-2	no	15.210	14.287	EPSD	ICGC;COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P06401	PGR	P28482	MAPK1	S345	P341L	341	Missense	distal	-4	no	15.210	14.906	EPSD	ICGC;COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P06401	PGR	P28482	MAPK1	S345	P341T	341	Missense	distal	-4	no	15.210	14.897	EPSD	ICGC;COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P06401	PGR	P28482	MAPK1	S345	P352Q	352	Missense	distal	7	no	15.210	15.340	EPSD	ICGC;COSMIC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P06401	PGR	P28482	MAPK1	T351	P352Q	352	Missense	proximal	1	no	13.423	4.929	EPSD	ICGC;COSMIC	8.102	Loss
CMGC_MAPK_ERK1_MAPK1_ST	P06401	PGR	P28482	MAPK1	S400	S400F	400	Missense	central	0	yes	13.209	0.000	EPSD	ICGC;COSMIC	8.102	Loss
CMGC_MAPK_ERK1_MAPK1_ST	P06401	PGR	P28482	MAPK1	S549	P555Q	555	Missense	distal	6	no	10.684	10.396	EPSD	ICGC;COSMIC;GDSC;CCLE	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P06401	PGR	P28482	MAPK1	S554	E560D	560	Missense	distal	6	no	12.386	12.306	EPSD	ICGC;COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P06401	PGR	P28482	MAPK1	S554	P555Q	555	Missense	proximal	1	no	12.386	3.892	EPSD	ICGC;COSMIC;GDSC;CCLE	8.102	Loss
CMGC_MAPK_ERK1_MAPK1_ST	P46695	IER3	P28482	MAPK1	T18	T23I	23	Missense	distal	5	no	15.252	15.009	PhosphoSitePlus	ICGC;COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P46695	IER3	P28482	MAPK1	T37	S31F	31	Missense	distal	-6	no	9.288	9.204	EPSD	ICGC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P46695	IER3	P28482	MAPK1	T123	S126F	126	Missense	distal	3	no	14.252	14.314	EPSD	ICGC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P46695	IER3	P28482	MAPK1	S126	S126F	126	Missense	central	0	yes	10.888	0.000	EPSD	ICGC	8.102	Loss
CMGC_MAPK_ERK1_MAPK1_ST	Q15596	NCOA2	P28482	MAPK1	S29	P30T	30	Missense	proximal	1	no	14.576	6.077	EPSD	ICGC	8.102	Loss
CMGC_MAPK_ERK1_MAPK1_ST	Q15596	NCOA2	P28482	MAPK1	T197	S195R	195	Missense	proximal	-2	no	7.353	8.369	EPSD	ICGC;COSMIC	8.102	Gain
CMGC_MAPK_ERK1_MAPK1_ST	Q15596	NCOA2	P28482	MAPK1	S267	R273C	273	Missense	distal	6	no	8.540	7.780	EPSD	ICGC;COSMIC	8.102	Loss
CMGC_MAPK_ERK1_MAPK1_ST	Q15596	NCOA2	P28482	MAPK1	S267	T271N	271	Missense	distal	4	no	8.540	8.616	EPSD	ICGC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q15596	NCOA2	P28482	MAPK1	S267	P262Q	262	Missense	distal	-5	no	8.540	8.665	EPSD	ICGC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q15596	NCOA2	P28482	MAPK1	S269	R273C	273	Missense	distal	4	no	9.425	9.166	EPSD	ICGC;COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q15596	NCOA2	P28482	MAPK1	S269	T271N	271	Missense	proximal	2	no	9.425	9.399	EPSD	ICGC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q15596	NCOA2	P28482	MAPK1	S269	P262Q	262	Missense	distal	-7	no	9.425	9.428	EPSD	ICGC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q15596	NCOA2	P28482	MAPK1	S269	D275N	275	Missense	distal	6	no	9.425	9.374	EPSD	ICGC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q15596	NCOA2	P28482	MAPK1	S402	P403T	403	Missense	proximal	1	no	13.635	5.137	EPSD	ICGC	8.102	Loss
CMGC_MAPK_ERK1_MAPK1_ST	Q15596	NCOA2	P28482	MAPK1	S402	L395M	395	Missense	distal	-7	no	13.635	13.626	EPSD	ICGC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q15596	NCOA2	P28482	MAPK1	S402	A407P	407	Missense	distal	5	no	13.635	13.777	EPSD	ICGC;COSMIC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q15596	NCOA2	P28482	MAPK1	S402	P403H	403	Missense	proximal	1	no	13.635	5.812	EPSD	ICGC;COSMIC	8.102	Loss
CMGC_MAPK_ERK1_MAPK1_ST	Q15596	NCOA2	P28482	MAPK1	T457	A455E	455	Missense	proximal	-2	no	12.271	13.038	EPSD	ICGC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q15596	NCOA2	P28482	MAPK1	S469	L465I	465	Missense	distal	-4	no	12.831	12.464	EPSD	ICGC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q15596	NCOA2	P28482	MAPK1	S487	P488L	488	Missense	proximal	1	no	11.426	2.616	EPSD	ICGC;COSMIC	8.102	Loss
CMGC_MAPK_ERK1_MAPK1_ST	Q15596	NCOA2	P28482	MAPK1	S487	H490N	490	Missense	distal	3	no	11.426	11.328	EPSD	ICGC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q15596	NCOA2	P28482	MAPK1	S493	S499N	499	Missense	distal	6	no	15.547	15.451	EPSD	ICGC;COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q15596	NCOA2	P28482	MAPK1	S493	P488L	488	Missense	distal	-5	no	15.547	15.696	EPSD	ICGC;COSMIC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q15596	NCOA2	P28482	MAPK1	S493	H490N	490	Missense	distal	-3	no	15.547	15.735	EPSD	ICGC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q15596	NCOA2	P28482	MAPK1	S499	S499N	499	Missense	central	0	yes	12.253	0.000	EPSD	ICGC;COSMIC	8.102	Loss
CMGC_MAPK_ERK1_MAPK1_ST	Q15596	NCOA2	P28482	MAPK1	S554	L552S	552	Missense	proximal	-2	no	14.431	13.514	EPSD	ICGC;COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q15596	NCOA2	P28482	MAPK1	S554	S551L	551	Missense	distal	-3	no	14.431	14.224	EPSD	ICGC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q15596	NCOA2	P28482	MAPK1	S699	A704T	704	Missense	distal	5	no	11.988	12.074	EPSD	ICGC;COSMIC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q15596	NCOA2	P28482	MAPK1	S736	A743T	743	Missense	distal	7	no	16.880	16.851	PhosphoSitePlus	ICGC;COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q15596	NCOA2	P28482	MAPK1	S736	A743E	743	Missense	distal	7	no	16.880	16.640	PhosphoSitePlus	ICGC;COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q15596	NCOA2	P28482	MAPK1	T763	D756Y	756	Missense	distal	-7	no	14.681	14.648	EPSD	ICGC;COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q15596	NCOA2	P28482	MAPK1	T854	K860I	860	Missense	distal	6	no	17.168	16.444	EPSD	ICGC;COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q15596	NCOA2	P28482	MAPK1	S895	I891T	891	Missense	distal	-4	no	17.270	17.627	EPSD	ICGC;COSMIC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q15596	NCOA2	P28482	MAPK1	S895	L889H	889	Missense	distal	-6	no	17.270	17.287	EPSD	ICGC;COSMIC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q15596	NCOA2	P28482	MAPK1	S895	D890N	890	Missense	distal	-5	no	17.270	17.226	EPSD	ICGC;COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q15596	NCOA2	P28482	MAPK1	S1059	P1066Q	1066	Missense	distal	7	no	11.342	11.472	EPSD	ICGC;COSMIC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q15596	NCOA2	P28482	MAPK1	S1072	P1068A	1068	Missense	distal	-4	no	14.422	14.129	EPSD	ICGC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q15596	NCOA2	P28482	MAPK1	S1072	S1072F	1072	Missense	central	0	yes	14.422	0.000	EPSD	ICGC;COSMIC	8.102	Loss
CMGC_MAPK_ERK1_MAPK1_ST	Q15596	NCOA2	P28482	MAPK1	S1072	P1066Q	1066	Missense	distal	-6	no	14.422	14.407	EPSD	ICGC;COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q15596	NCOA2	P28482	MAPK1	T1273	S1275N	1275	Missense	proximal	2	no	12.258	12.210	EPSD	ICGC;COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q15596	NCOA2	P28482	MAPK1	T1273	A1278D	1278	Missense	distal	5	no	12.258	12.443	EPSD	ICGC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q15596	NCOA2	P28482	MAPK1	T1273	L1270F	1270	Missense	distal	-3	no	12.258	12.233	EPSD	ICGC;COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P17676	CEBPB	P28482	MAPK1	S76	I73M	73	Missense	distal	-3	no	11.892	11.896	EPSD	ICGC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P17676	CEBPB	P28482	MAPK1	S141	L142P	142	Missense	proximal	1	no	5.042	13.852	EPSD	ICGC;COSMIC	8.102	Gain
CMGC_MAPK_ERK1_MAPK1_ST	P17676	CEBPB	P28482	MAPK1	S231	L224I	224	Missense	distal	-7	no	14.407	14.387	EPSD	ICGC;COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P17676	CEBPB	P28482	MAPK1	S231	P238H	238	Missense	distal	7	no	14.407	14.640	EPSD	ICGC;COSMIC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P17676	CEBPB	P28482	MAPK1	T235	P238H	238	Missense	distal	3	no	17.180	17.268	PhosphoSitePlus	ICGC;COSMIC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P17676	CEBPB	P28482	MAPK1	S237	P238H	238	Missense	proximal	1	no	13.166	5.342	EPSD	ICGC;COSMIC	8.102	Loss
CMGC_MAPK_ERK1_MAPK1_ST	P05198	EIF2S1	P28482	MAPK1	S26	V19L	19	Missense	distal	-7	no	9.629	9.636	EPSD	ICGC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P05198	EIF2S1	P28482	MAPK1	S26	A32S	32	Missense	distal	6	no	9.629	9.926	EPSD	ICGC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P05198	EIF2S1	P28482	MAPK1	S35	A32S	32	Missense	distal	-3	no	8.704	8.894	EPSD	ICGC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P05198	EIF2S1	P28482	MAPK1	S91	D84Y	84	Missense	distal	-7	no	17.128	17.096	EPSD	ICGC;COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P05198	EIF2S1	P28482	MAPK1	T185	R183H	183	Missense	proximal	-2	no	12.946	12.010	EPSD	ICGC;COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P05198	EIF2S1	P28482	MAPK1	T185	R182G	182	Missense	distal	-3	no	12.946	12.777	EPSD	ICGC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P05198	EIF2S1	P28482	MAPK1	T185	A188S	188	Missense	distal	3	no	12.946	12.937	EPSD	ICGC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	O60504	SORBS3	P28482	MAPK1	S28	L22H	22	Missense	distal	-6	no	8.365	8.383	EPSD	ICGC;COSMIC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	O60504	SORBS3	P28482	MAPK1	T64	G62V	62	Missense	proximal	-2	no	11.635	12.956	EPSD	ICGC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	O60504	SORBS3	P28482	MAPK1	T64	P65L	65	Missense	proximal	1	no	11.635	2.825	EPSD	ICGC	8.102	Loss
CMGC_MAPK_ERK1_MAPK1_ST	O60504	SORBS3	P28482	MAPK1	S97	Q98H	98	Missense	proximal	1	no	7.880	8.550	EPSD	ICGC	8.102	Gain
CMGC_MAPK_ERK1_MAPK1_ST	O60504	SORBS3	P28482	MAPK1	T191	S197I	197	Missense	distal	6	no	8.558	7.891	EPSD	ICGC	8.102	Loss
CMGC_MAPK_ERK1_MAPK1_ST	O60504	SORBS3	P28482	MAPK1	T191	P189S	189	Missense	proximal	-2	no	8.558	5.724	EPSD	ICGC;COSMIC	8.102	Loss
CMGC_MAPK_ERK1_MAPK1_ST	O60504	SORBS3	P28482	MAPK1	T191	R196C	196	Missense	distal	5	no	8.558	8.126	EPSD	ICGC;COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	O60504	SORBS3	P28482	MAPK1	S299	S299P	299	Missense	central	0	yes	14.575	0.000	EPSD	ICGC;COSMIC	8.102	Loss
CMGC_MAPK_ERK1_MAPK1_ST	O60504	SORBS3	P28482	MAPK1	S303	S299P	299	Missense	distal	-4	no	15.032	15.115	EPSD	ICGC;COSMIC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	O60504	SORBS3	P28482	MAPK1	S337	L338P	338	Missense	proximal	1	no	3.522	12.332	EPSD	ICGC;COSMIC	8.102	Gain
CMGC_MAPK_ERK1_MAPK1_ST	O60504	SORBS3	P28482	MAPK1	S339	S339I	339	Missense	central	0	yes	13.401	0.000	EPSD	ICGC	8.102	Loss
CMGC_MAPK_ERK1_MAPK1_ST	O60504	SORBS3	P28482	MAPK1	S339	L338P	338	Missense	proximal	-1	no	13.401	13.461	EPSD	ICGC;COSMIC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	O60504	SORBS3	P28482	MAPK1	S348	R354M	354	Missense	distal	6	no	12.996	12.670	EPSD	ICGC;COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	O60504	SORBS3	P28482	MAPK1	S373	S373R	373	Missense	central	0	yes	13.044	0.000	EPSD	ICGC	8.102	Loss
CMGC_MAPK_ERK1_MAPK1_ST	O60504	SORBS3	P28482	MAPK1	S373	G372V	372	Missense	proximal	-1	no	13.044	13.072	EPSD	ICGC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	O60504	SORBS3	P28482	MAPK1	S373	G371R	371	Missense	proximal	-2	no	13.044	14.419	EPSD	ICGC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	O60504	SORBS3	P28482	MAPK1	S508	G503V	503	Missense	distal	-5	no	9.493	9.522	EPSD	ICGC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	O60504	SORBS3	P28482	MAPK1	S508	S513P	513	Missense	distal	5	no	9.493	9.475	EPSD	ICGC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	O60504	SORBS3	P28482	MAPK1	S508	Q502K	502	Missense	distal	-6	no	9.493	9.494	EPSD	ICGC;COSMIC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	O60504	SORBS3	P28482	MAPK1	S530	D523N	523	Missense	distal	-7	no	16.487	16.488	EPSD	ICGC;COSMIC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	O60504	SORBS3	P28482	MAPK1	S530	R532H	532	Missense	proximal	2	no	16.487	16.244	EPSD	ICGC;COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	O60504	SORBS3	P28482	MAPK1	S530	R532S	532	Missense	proximal	2	no	16.487	16.346	EPSD	ICGC;COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	O60504	SORBS3	P28482	MAPK1	T534	R541L	541	Missense	distal	7	no	8.101	8.386	EPSD	ICGC	8.102	Gain
CMGC_MAPK_ERK1_MAPK1_ST	O60504	SORBS3	P28482	MAPK1	S544	S545P	545	Missense	proximal	1	no	2.028	11.423	EPSD	ICGC	8.102	Gain
CMGC_MAPK_ERK1_MAPK1_ST	O60504	SORBS3	P28482	MAPK1	S545	S547L	547	Missense	proximal	2	no	16.974	16.854	EPSD	ICGC;COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	O60504	SORBS3	P28482	MAPK1	S545	S545P	545	Missense	central	0	yes	16.974	0.000	EPSD	ICGC	8.102	Loss
CMGC_MAPK_ERK1_MAPK1_ST	O60504	SORBS3	P28482	MAPK1	S545	R541L	541	Missense	distal	-4	no	16.974	16.759	EPSD	ICGC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	O60504	SORBS3	P28482	MAPK1	S547	S545P	545	Missense	proximal	-2	no	6.733	9.567	EPSD	ICGC	8.102	Gain
CMGC_MAPK_ERK1_MAPK1_ST	O60504	SORBS3	P28482	MAPK1	S551	S547L	547	Missense	distal	-4	no	15.122	14.901	EPSD	ICGC;COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	O60504	SORBS3	P28482	MAPK1	S551	I556T	556	Missense	distal	5	no	15.122	15.365	EPSD	ICGC;COSMIC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	O60504	SORBS3	P28482	MAPK1	S551	S545P	545	Missense	distal	-6	no	15.122	15.148	EPSD	ICGC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	O60504	SORBS3	P28482	MAPK1	S563	I556T	556	Missense	distal	-7	no	12.854	12.869	EPSD	ICGC;COSMIC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	O60504	SORBS3	P28482	MAPK1	T585	G584A	584	Missense	proximal	-1	no	14.541	14.559	EPSD	ICGC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q13480	GAB1	P28482	MAPK1	S244	Y242H	242	Missense	proximal	-2	no	13.472	12.834	EPSD	ICGC;COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q13480	GAB1	P28482	MAPK1	S264	L270S	270	Missense	distal	6	no	8.666	9.072	EPSD	ICGC;GDSC;CCLE	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q13480	GAB1	P28482	MAPK1	S274	S277I	277	Missense	distal	3	no	13.799	13.858	EPSD	ICGC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q13480	GAB1	P28482	MAPK1	S274	L270S	270	Missense	distal	-4	no	13.799	14.020	EPSD	ICGC;GDSC;CCLE	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q13480	GAB1	P28482	MAPK1	S277	S277I	277	Missense	central	0	yes	8.815	0.000	EPSD	ICGC	8.102	Loss
CMGC_MAPK_ERK1_MAPK1_ST	Q13480	GAB1	P28482	MAPK1	S277	L270S	270	Missense	distal	-7	no	8.815	8.822	EPSD	ICGC;GDSC;CCLE	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q13480	GAB1	P28482	MAPK1	T289	S295I	295	Missense	distal	6	no	16.048	15.381	EPSD	ICGC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q13480	GAB1	P28482	MAPK1	T289	G292W	292	Missense	distal	3	no	16.048	16.160	EPSD	ICGC;COSMIC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q13480	GAB1	P28482	MAPK1	T312	P311L	311	Missense	proximal	-1	no	17.126	17.066	EPSD	ICGC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q13480	GAB1	P28482	MAPK1	S381	G379W	379	Missense	proximal	-2	no	15.553	16.005	EPSD	ICGC;COSMIC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q13480	GAB1	P28482	MAPK1	S381	P376T	376	Missense	distal	-5	no	15.553	15.655	EPSD	ICGC;COSMIC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q13480	GAB1	P28482	MAPK1	S419	L420P	420	Missense	proximal	1	no	4.895	13.705	EPSD	ICGC	8.102	Gain
CMGC_MAPK_ERK1_MAPK1_ST	Q13480	GAB1	P28482	MAPK1	S437	V438F	438	Missense	proximal	1	no	5.358	8.329	EPSD	ICGC	8.102	Gain
CMGC_MAPK_ERK1_MAPK1_ST	Q13480	GAB1	P28482	MAPK1	S454	V448I	448	Missense	distal	-6	no	16.090	16.049	EPSD	ICGC;COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q13480	GAB1	P28482	MAPK1	S454	M450I	450	Missense	distal	-4	no	16.090	15.885	EPSD	ICGC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q13480	GAB1	P28482	MAPK1	T476	D481Y	481	Missense	distal	5	no	15.592	15.278	PhosphoSitePlus	ICGC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q13480	GAB1	P28482	MAPK1	T476	G478R	478	Missense	proximal	2	no	15.592	15.686	PhosphoSitePlus	ICGC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q13480	GAB1	P28482	MAPK1	T476	M475I	475	Missense	proximal	-1	no	15.592	15.576	PhosphoSitePlus	ICGC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q13480	GAB1	P28482	MAPK1	S500	R498M	498	Missense	proximal	-2	no	15.471	13.275	EPSD	ICGC;COSMIC;GDSC;CCLE	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q13480	GAB1	P28482	MAPK1	T503	R498M	498	Missense	distal	-5	no	16.804	16.909	EPSD	ICGC;COSMIC;GDSC;CCLE	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q13480	GAB1	P28482	MAPK1	T638	G635C	635	Missense	distal	-3	no	14.698	14.184	EPSD	ICGC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P10275	AR	P28482	MAPK1	T18	A22S	22	Missense	distal	4	no	8.910	9.003	EPSD	ICGC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P10275	AR	P28482	MAPK1	T18	P12T	12	Missense	distal	-6	no	8.910	8.860	EPSD	ICGC;COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P10275	AR	P28482	MAPK1	S96	E93K	93	Missense	distal	-3	no	11.382	11.304	EPSD	ICGC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P10275	AR	P28482	MAPK1	S258	G260V	260	Missense	proximal	2	no	13.952	13.880	EPSD	ICGC;COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P10275	AR	P28482	MAPK1	T282	A288T	288	Missense	distal	6	no	13.218	13.305	EPSD	ICGC;COSMIC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P10275	AR	P28482	MAPK1	T282	R280L	280	Missense	proximal	-2	no	13.218	13.120	EPSD	ICGC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P10275	AR	P28482	MAPK1	T282	A288D	288	Missense	distal	6	no	13.218	13.469	EPSD	ICGC;COSMIC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P10275	AR	P28482	MAPK1	S310	T317A	317	Missense	distal	7	no	12.629	12.658	EPSD	ICGC;COSMIC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P10275	AR	P28482	MAPK1	S310	T303S	303	Missense	distal	-7	no	12.629	12.641	EPSD	ICGC;COSMIC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P10275	AR	P28482	MAPK1	S310	G314R	314	Missense	distal	4	no	12.629	12.655	EPSD	ICGC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P10275	AR	P28482	MAPK1	S516	Y514H	514	Missense	proximal	-2	no	13.880	13.242	PhosphoSitePlus	ICGC;GDSC;CCLE	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P10275	AR	P28482	MAPK1	S516	S516I	516	Missense	central	0	yes	13.880	0.000	PhosphoSitePlus	ICGC	8.102	Loss
CMGC_MAPK_ERK1_MAPK1_ST	P10275	AR	P28482	MAPK1	S516	V509L	509	Missense	distal	-7	no	13.880	13.886	PhosphoSitePlus	ICGC;COSMIC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q14934	NFATC4	P28482	MAPK1	S73	R77H	77	Missense	distal	4	no	13.328	13.186	EPSD	ICGC;COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q14934	NFATC4	P28482	MAPK1	S73	P74L	74	Missense	proximal	1	no	13.328	4.518	EPSD	ICGC;COSMIC	8.102	Loss
CMGC_MAPK_ERK1_MAPK1_ST	Q14934	NFATC4	P28482	MAPK1	S311	P314L	314	Missense	distal	3	no	15.778	15.867	EPSD	ICGC;COSMIC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q14934	NFATC4	P28482	MAPK1	S395	P396S	396	Missense	proximal	1	no	13.217	3.822	EPSD	ICGC;COSMIC	8.102	Loss
CMGC_MAPK_ERK1_MAPK1_ST	Q14934	NFATC4	P28482	MAPK1	S592	V598F	598	Missense	distal	6	no	13.576	13.350	EPSD	ICGC;COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q14934	NFATC4	P28482	MAPK1	S592	V588A	588	Missense	distal	-4	no	13.576	13.637	EPSD	ICGC;COSMIC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q14934	NFATC4	P28482	MAPK1	S716	F715C	715	Missense	proximal	-1	no	13.971	13.939	EPSD	ICGC;COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q14934	NFATC4	P28482	MAPK1	S819	P820S	820	Missense	proximal	1	no	17.762	8.367	EPSD	ICGC;COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q13285	NR5A1	P28482	MAPK1	S203	A202V	202	Missense	proximal	-1	no	15.435	15.446	PhosphoSitePlus	ICGC;COSMIC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q13285	NR5A1	P28482	MAPK1	S203	P207H	207	Missense	distal	4	no	15.435	15.260	PhosphoSitePlus	ICGC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P02686	MBP	P28482	MAPK1	S16	N22K	22	Missense	distal	6	no	8.015	8.168	EPSD	ICGC;COSMIC	8.102	Gain
CMGC_MAPK_ERK1_MAPK1_ST	P02686	MBP	P28482	MAPK1	S26	N22K	22	Missense	distal	-4	no	8.090	8.121	EPSD	ICGC;COSMIC	8.102	Gain
CMGC_MAPK_ERK1_MAPK1_ST	Q9UPT5	EXOC7	P28482	MAPK1	S82	C83Y	83	Missense	proximal	1	no	1.775	8.215	EPSD	ICGC;COSMIC	8.102	Gain
CMGC_MAPK_ERK1_MAPK1_ST	Q9UPT5	EXOC7	P28482	MAPK1	S130	S130R	130	Missense	central	0	yes	14.439	0.000	EPSD	ICGC	8.102	Loss
CMGC_MAPK_ERK1_MAPK1_ST	Q9UPT5	EXOC7	P28482	MAPK1	S250	P248S	248	Missense	proximal	-2	no	17.902	15.068	PhosphoSitePlus	ICGC	8.102	Down-regulation
CMGC_GSK_GSK3B_ST	P49841	GSK3B	P49841-2	GSK3B	T7	A11S	11	Missense	distal	4	no	4.452	6.864	EPSD	ICGC;COSMIC	6.007	Gain
CMGC_GSK_GSK3B_ST	P49841	GSK3B	P49841-2	GSK3B	S9	A11S	11	Missense	proximal	2	no	6.632	6.624	EPSD	ICGC;COSMIC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	P49841	GSK3B	P49841-2	GSK3B	T43	D49E	49	Missense	distal	6	no	7.636	7.638	EPSD	ICGC	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	P49841	GSK3B	P49841-2	GSK3B	S55	D49E	49	Missense	distal	-6	no	7.192	7.155	EPSD	ICGC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	P49841	GSK3B	P49841-2	GSK3B	S55	Q52K	52	Missense	distal	-3	no	7.192	7.186	EPSD	ICGC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	P49841	GSK3B	P49841-2	GSK3B	S55	E53K	53	Missense	proximal	-2	no	7.192	7.161	EPSD	ICGC;COSMIC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	P49841	GSK3B	P49841-2	GSK3B	S215	S219Y	219	Missense	distal	4	no	7.507	3.994	EPSD	ICGC;COSMIC	6.007	Loss
CMGC_GSK_GSK3B_ST	P49841	GSK3B	P49841-2	GSK3B	S215	P212T	212	Missense	distal	-3	no	7.507	7.648	EPSD	ICGC	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	P49841	GSK3B	P49841-2	GSK3B	S219	S219Y	219	Missense	central	0	yes	6.818	0.000	EPSD	ICGC;COSMIC	6.007	Loss
CMGC_GSK_GSK3B_ST	P49841	GSK3B	P49841-2	GSK3B	S219	P212T	212	Missense	distal	-7	no	6.818	6.847	EPSD	ICGC	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	P49841	GSK3B	P49841-2	GSK3B	T275	I270V	270	Missense	distal	-5	no	7.582	7.689	EPSD	ICGC;COSMIC	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	P49841	GSK3B	P49841-2	GSK3B	T275	R278K	278	Missense	distal	3	no	7.582	7.826	EPSD	ICGC	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	P49841	GSK3B	P49841-2	GSK3B	T275	L273R	273	Missense	proximal	-2	no	7.582	7.541	EPSD	ICGC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	P49841	GSK3B	P49841-2	GSK3B	T275	L273M	273	Missense	proximal	-2	no	7.582	7.325	EPSD	ICGC;COSMIC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	P49841	GSK3B	P49841-2	GSK3B	T390	S389P	389	Missense	proximal	-1	no	5.963	6.019	EPSD	ICGC;COSMIC	6.007	Gain
CMGC_GSK_GSK3A_ST	P10636	MAPT	P49840	GSK3A	T101	P98S	98	Missense	distal	-3	no	73.952	73.313	EPSD	ICGC	72.838	Down-regulation
CMGC_GSK_GSK3A_ST	P10636	MAPT	P49840	GSK3A	T102	P98S	98	Missense	distal	-4	no	76.454	80.040	EPSD	ICGC	72.838	Up-regulation
CMGC_GSK_GSK3A_ST	P10636	MAPT	P49840	GSK3A	T111	D116E	116	Missense	distal	5	no	74.941	76.398	EPSD	ICGC;COSMIC	72.838	Up-regulation
CMGC_GSK_GSK3A_ST	P10636	MAPT	P49840	GSK3A	S171	R164T	164	Missense	distal	-7	no	81.434	83.189	EPSD	ICGC;COSMIC	72.838	Up-regulation
CMGC_GSK_GSK3A_ST	P10636	MAPT	P49840	GSK3A	S171	A166T	166	Missense	distal	-5	no	81.434	80.705	EPSD	ICGC	72.838	Down-regulation
CMGC_GSK_GSK3A_ST	P10636	MAPT	P49840	GSK3A	S227	P233H	233	Missense	distal	6	no	77.653	79.989	EPSD	ICGC;COSMIC	72.838	Up-regulation
CMGC_GSK_GSK3A_ST	P10636	MAPT	P49840	GSK3A	S227	S232F	232	Missense	distal	5	no	77.653	80.163	EPSD	ICGC	72.838	Up-regulation
CMGC_GSK_GSK3A_ST	P10636	MAPT	P49840	GSK3A	S227	D225N	225	Missense	proximal	-2	no	77.653	77.654	EPSD	ICGC	72.838	Up-regulation
CMGC_GSK_GSK3A_ST	P10636	MAPT	P49840	GSK3A	S227	V224I	224	Missense	distal	-3	no	77.653	75.304	EPSD	ICGC;COSMIC	72.838	Down-regulation
CMGC_GSK_GSK3A_ST	P10636	MAPT	P49840	GSK3A	S228	P233H	233	Missense	distal	5	no	92.623	80.983	EPSD	ICGC;COSMIC	72.838	Down-regulation
CMGC_GSK_GSK3A_ST	P10636	MAPT	P49840	GSK3A	S228	S232F	232	Missense	distal	4	no	92.623	70.332	EPSD	ICGC	72.838	Loss
CMGC_GSK_GSK3A_ST	P10636	MAPT	P49840	GSK3A	S228	D225N	225	Missense	distal	-3	no	92.623	92.409	EPSD	ICGC	72.838	Down-regulation
CMGC_GSK_GSK3A_ST	P10636	MAPT	P49840	GSK3A	S228	V224I	224	Missense	distal	-4	no	92.623	92.615	EPSD	ICGC;COSMIC	72.838	Down-regulation
CMGC_GSK_GSK3A_ST	P10636	MAPT	P49840	GSK3A	S232	P233H	233	Missense	proximal	1	no	85.793	59.379	EPSD	ICGC;COSMIC	72.838	Loss
CMGC_GSK_GSK3A_ST	P10636	MAPT	P49840	GSK3A	S232	S232F	232	Missense	central	0	yes	85.793	0.000	EPSD	ICGC	72.838	Loss
CMGC_GSK_GSK3A_ST	P10636	MAPT	P49840	GSK3A	S232	D225N	225	Missense	distal	-7	no	85.793	87.493	EPSD	ICGC	72.838	Up-regulation
CMGC_GSK_GSK3A_ST	P10636	MAPT	P49840	GSK3A	S232	P239Q	239	Missense	distal	7	no	85.793	85.420	EPSD	ICGC;COSMIC	72.838	Down-regulation
CMGC_GSK_GSK3A_ST	P10636	MAPT	P49840	GSK3A	S341	T346I	346	Missense	distal	5	no	79.730	68.298	EPSD	ICGC;COSMIC	72.838	Loss
CMGC_GSK_GSK3A_ST	P10636	MAPT	P49840	GSK3A	S341	A337V	337	Missense	distal	-4	no	79.730	78.900	EPSD	ICGC	72.838	Down-regulation
CMGC_GSK_GSK3A_ST	P10636	MAPT	P49840	GSK3A	S341	D345E	345	Missense	distal	4	no	79.730	80.113	EPSD	ICGC;COSMIC	72.838	Up-regulation
CMGC_GSK_GSK3A_ST	P10636	MAPT	P49840	GSK3A	S355	A349T	349	Missense	distal	-6	no	75.547	74.965	EPSD	ICGC;COSMIC	72.838	Down-regulation
CMGC_GSK_GSK3A_ST	P10636	MAPT	P49840	GSK3A	S437	Y441H	441	Missense	distal	4	no	72.985	50.572	EPSD	ICGC;COSMIC	72.838	Loss
CMGC_GSK_GSK3A_ST	P10636	MAPT	P49840	GSK3A	S438	Y441H	441	Missense	distal	3	no	99.970	100.372	EPSD	ICGC;COSMIC	72.838	Up-regulation
CMGC_GSK_GSK3A_ST	P10636	MAPT	P49840	GSK3A	S447	Y441H	441	Missense	distal	-6	no	81.913	82.110	EPSD	ICGC;COSMIC	72.838	Up-regulation
CMGC_GSK_GSK3A_ST	P10636	MAPT	P49840	GSK3A	S515	G521R	521	Missense	distal	6	no	88.526	90.885	EPSD	ICGC;COSMIC	72.838	Up-regulation
CMGC_GSK_GSK3A_ST	P10636	MAPT	P49840	GSK3A	S516	G521R	521	Missense	distal	5	no	94.559	95.005	EPSD	ICGC;COSMIC	72.838	Up-regulation
CMGC_GSK_GSK3A_ST	P10636	MAPT	P49840	GSK3A	S519	G521R	521	Missense	proximal	2	no	91.776	93.411	EPSD	ICGC;COSMIC	72.838	Up-regulation
CMGC_GSK_GSK3A_ST	P10636	MAPT	P49840	GSK3A	T522	G521R	521	Missense	proximal	-1	no	90.876	90.602	EPSD	ICGC;COSMIC	72.838	Down-regulation
CMGC_GSK_GSK3A_ST	P10636	MAPT	P49840	GSK3A	S525	G521R	521	Missense	distal	-4	no	84.428	85.897	EPSD	ICGC;COSMIC	72.838	Up-regulation
CMGC_GSK_GSK3A_ST	P10636	MAPT	P49840	GSK3A	S527	G521R	521	Missense	distal	-6	no	90.290	90.448	EPSD	ICGC;COSMIC	72.838	Up-regulation
CMGC_GSK_GSK3A_ST	Q14449	GRB14	P49840	GSK3A	S362	P367H	367	Missense	distal	5	no	81.324	69.684	PhosphoSitePlus;EPSD	ICGC;COSMIC	72.838	Loss
CMGC_GSK_GSK3A_ST	Q14449	GRB14	P49840	GSK3A	S362	M368I	368	Missense	distal	6	no	81.324	80.294	PhosphoSitePlus;EPSD	ICGC;COSMIC	72.838	Down-regulation
CMGC_GSK_GSK3A_ST	Q14449	GRB14	P49840	GSK3A	S366	P367H	367	Missense	proximal	1	no	87.312	60.899	EPSD;PhosphoSitePlus	ICGC;COSMIC	72.838	Loss
CMGC_GSK_GSK3A_ST	Q14449	GRB14	P49840	GSK3A	S366	M368I	368	Missense	proximal	2	no	87.312	84.759	EPSD;PhosphoSitePlus	ICGC;COSMIC	72.838	Down-regulation
CMGC_GSK_GSK3A_ST	Q8NHW3	MAFA	P49840	GSK3A	T53	S56N	56	Missense	distal	3	no	92.645	95.329	EPSD;PhosphoSitePlus	ICGC;COSMIC	72.838	Up-regulation
CMGC_GSK_GSK3A_ST	Q8NHW3	MAFA	P49840	GSK3A	T53	S52L	52	Missense	proximal	-1	no	92.645	92.388	EPSD;PhosphoSitePlus	ICGC;COSMIC	72.838	Down-regulation
CMGC_GSK_GSK3A_ST	Q8NHW3	MAFA	P49840	GSK3A	T57	S56N	56	Missense	proximal	-1	no	75.822	75.233	EPSD;PhosphoSitePlus	ICGC;COSMIC	72.838	Down-regulation
CMGC_GSK_GSK3A_ST	Q8NHW3	MAFA	P49840	GSK3A	T57	S52L	52	Missense	distal	-5	no	75.822	74.172	EPSD;PhosphoSitePlus	ICGC;COSMIC	72.838	Down-regulation
CMGC_GSK_GSK3A_ST	Q8NHW3	MAFA	P49840	GSK3A	S61	S56N	56	Missense	distal	-5	no	79.102	78.459	PhosphoSitePlus;EPSD	ICGC;COSMIC	72.838	Down-regulation
CMGC_GSK_GSK3A_ST	Q14596	NBR1	P49840	GSK3A	S123	V120I	120	Missense	distal	-3	no	86.314	83.966	EPSD	ICGC	72.838	Down-regulation
CMGC_GSK_GSK3A_ST	Q14596	NBR1	P49840	GSK3A	S276	P281S	281	Missense	distal	5	no	81.543	75.986	EPSD	ICGC;COSMIC	72.838	Down-regulation
CMGC_GSK_GSK3A_ST	Q14596	NBR1	P49840	GSK3A	S340	P344L	344	Missense	distal	4	no	77.016	77.592	EPSD	ICGC	72.838	Up-regulation
CMGC_GSK_GSK3A_ST	Q14596	NBR1	P49840	GSK3A	S340	Q339K	339	Missense	proximal	-1	no	77.016	75.182	EPSD	ICGC;COSMIC	72.838	Down-regulation
CMGC_GSK_GSK3A_ST	Q14596	NBR1	P49840	GSK3A	T586	H579Y	579	Missense	distal	-7	no	83.710	83.293	PhosphoSitePlus	ICGC;COSMIC	72.838	Down-regulation
CMGC_GSK_GSK3A_ST	Q14596	NBR1	P49840	GSK3A	T586	V585L	585	Missense	proximal	-1	no	83.710	83.220	PhosphoSitePlus	ICGC;COSMIC	72.838	Down-regulation
CMGC_GSK_GSK3A_ST	Q14596	NBR1	P49840	GSK3A	T586	P582T	582	Missense	distal	-4	no	83.710	88.105	PhosphoSitePlus	ICGC;COSMIC	72.838	Up-regulation
CMGC_GSK_GSK3A_ST	Q14596	NBR1	P49840	GSK3A	S833	P826S	826	Missense	distal	-7	no	80.995	80.840	EPSD	ICGC	72.838	Down-regulation
CMGC_GSK_GSK3A_ST	Q14596	NBR1	P49840	GSK3A	S833	P839Q	839	Missense	distal	6	no	80.995	82.905	EPSD	ICGC;COSMIC	72.838	Up-regulation
CMGC_GSK_GSK3A_ST	P20749	BCL3	P49840	GSK3A	S41	A46S	46	Missense	distal	5	no	76.510	77.430	EPSD	ICGC	72.838	Up-regulation
CMGC_GSK_GSK3A_ST	P20749	BCL3	P49840	GSK3A	S197	A200V	200	Missense	distal	3	no	82.065	81.300	EPSD	ICGC;COSMIC	72.838	Down-regulation
CMGC_GSK_GSK3A_ST	P20749	BCL3	P49840	GSK3A	T363	R364Q	364	Missense	proximal	1	no	81.408	79.384	EPSD	ICGC;COSMIC	72.838	Down-regulation
CMGC_GSK_GSK3A_ST	P20749	BCL3	P49840	GSK3A	T363	D356Y	356	Missense	distal	-7	no	81.408	83.569	EPSD	ICGC	72.838	Up-regulation
CMGC_GSK_GSK3A_ST	P20749	BCL3	P49840	GSK3A	S367	D372G	372	Missense	distal	5	no	83.205	84.484	EPSD	ICGC;COSMIC	72.838	Up-regulation
CMGC_GSK_GSK3A_ST	P20749	BCL3	P49840	GSK3A	S367	R364Q	364	Missense	distal	-3	no	83.205	82.856	EPSD	ICGC;COSMIC	72.838	Down-regulation
CMGC_GSK_GSK3A_ST	P20749	BCL3	P49840	GSK3A	S367	P371S	371	Missense	distal	4	no	83.205	89.191	EPSD	ICGC	72.838	Up-regulation
CMGC_GSK_GSK3A_ST	P20749	BCL3	P49840	GSK3A	S369	D372G	372	Missense	distal	3	no	75.204	72.727	EPSD	ICGC;COSMIC	72.838	Loss
CMGC_GSK_GSK3A_ST	P20749	BCL3	P49840	GSK3A	S369	R364Q	364	Missense	distal	-5	no	75.204	77.554	EPSD	ICGC;COSMIC	72.838	Up-regulation
CMGC_GSK_GSK3A_ST	P20749	BCL3	P49840	GSK3A	S369	P371S	371	Missense	proximal	2	no	75.204	74.516	EPSD	ICGC	72.838	Down-regulation
CMGC_GSK_GSK3A_ST	P20749	BCL3	P49840	GSK3A	S374	D372G	372	Missense	proximal	-2	no	88.220	88.367	EPSD	ICGC;COSMIC	72.838	Up-regulation
CMGC_GSK_GSK3A_ST	P20749	BCL3	P49840	GSK3A	S374	A379T	379	Missense	distal	5	no	88.220	89.816	EPSD	ICGC	72.838	Up-regulation
CMGC_GSK_GSK3A_ST	P20749	BCL3	P49840	GSK3A	S374	P371S	371	Missense	distal	-3	no	88.220	87.580	EPSD	ICGC	72.838	Down-regulation
CMGC_GSK_GSK3A_ST	P20749	BCL3	P49840	GSK3A	S378	D372G	372	Missense	distal	-6	no	85.952	84.931	EPSD	ICGC;COSMIC	72.838	Down-regulation
CMGC_GSK_GSK3A_ST	P20749	BCL3	P49840	GSK3A	S378	A379T	379	Missense	proximal	1	no	85.952	84.967	EPSD	ICGC	72.838	Down-regulation
CMGC_GSK_GSK3A_ST	P20749	BCL3	P49840	GSK3A	S378	P371S	371	Missense	distal	-7	no	85.952	85.796	EPSD	ICGC	72.838	Down-regulation
CMGC_GSK_GSK3A_ST	P20749	BCL3	P49840	GSK3A	S378	P383R	383	Missense	distal	5	no	85.952	80.807	EPSD	ICGC	72.838	Down-regulation
CMGC_GSK_GSK3A_ST	P20749	BCL3	P49840	GSK3A	S382	A379T	379	Missense	distal	-3	no	92.236	93.063	EPSD	ICGC	72.838	Up-regulation
CMGC_GSK_GSK3A_ST	P20749	BCL3	P49840	GSK3A	S382	P383R	383	Missense	proximal	1	no	92.236	83.583	EPSD	ICGC	72.838	Down-regulation
CMGC_GSK_GSK3A_ST	P20749	BCL3	P49840	GSK3A	S382	L389H	389	Missense	distal	7	no	92.236	92.795	EPSD	ICGC	72.838	Up-regulation
CMGC_GSK_GSK3A_ST	P20749	BCL3	P49840	GSK3A	S386	L389H	389	Missense	distal	3	no	68.110	74.934	EPSD	ICGC	72.838	Gain
CMGC_GSK_GSK3A_ST	P20749	BCL3	P49840	GSK3A	S402	P403T	403	Missense	proximal	1	no	97.336	82.684	PhosphoSitePlus;EPSD	ICGC;COSMIC	72.838	Down-regulation
CMGC_GSK_GSK3A_ST	P20749	BCL3	P49840	GSK3A	S402	P399Q	399	Missense	distal	-3	no	97.336	96.094	PhosphoSitePlus;EPSD	ICGC;COSMIC	72.838	Down-regulation
CMGC_GSK_GSK3A_ST	P20749	BCL3	P49840	GSK3A	S406	P403T	403	Missense	distal	-3	no	104.218	104.731	EPSD;PhosphoSitePlus	ICGC;COSMIC	72.838	Up-regulation
CMGC_GSK_GSK3A_ST	P20749	BCL3	P49840	GSK3A	S406	P411S	411	Missense	distal	5	no	104.218	98.661	EPSD;PhosphoSitePlus	ICGC;COSMIC	72.838	Down-regulation
CMGC_GSK_GSK3A_ST	P20749	BCL3	P49840	GSK3A	S406	P399Q	399	Missense	distal	-7	no	104.218	103.369	EPSD;PhosphoSitePlus	ICGC;COSMIC	72.838	Down-regulation
CMGC_GSK_GSK3A_ST	P49840	GSK3A	P49840	GSK3A	S41	G45D	45	Missense	distal	4	no	65.581	78.777	EPSD	ICGC	72.838	Gain
CMGC_GSK_GSK3A_ST	P49840	GSK3A	P49840	GSK3A	S65	G70S	70	Missense	distal	5	no	75.355	75.389	EPSD	ICGC;COSMIC	72.838	Up-regulation
CMGC_GSK_GSK3A_ST	P49840	GSK3A	P49840	GSK3A	S65	G66W	66	Missense	proximal	1	no	75.355	13.136	EPSD	ICGC	72.838	Loss
CMGC_GSK_GSK3A_ST	P49840	GSK3A	P49840	GSK3A	S65	S63L	63	Missense	proximal	-2	no	75.355	74.640	EPSD	ICGC	72.838	Down-regulation
CMGC_GSK_GSK3A_ST	P49840	GSK3A	P49840	GSK3A	S97	D96E	96	Missense	proximal	-1	no	77.022	78.711	EPSD	ICGC;COSMIC	72.838	Up-regulation
CMGC_GSK_GSK3A_ST	P49840	GSK3A	P49840	GSK3A	S97	R95G	95	Missense	proximal	-2	no	77.022	75.920	EPSD	ICGC;COSMIC	72.838	Down-regulation
CMGC_GSK_GSK3A_ST	P49840	GSK3A	P49840	GSK3A	S97	G98R	98	Missense	proximal	1	no	77.022	78.845	EPSD	ICGC	72.838	Up-regulation
CMGC_GSK_GSK3A_ST	P49840	GSK3A	P49840	GSK3A	S97	V103A	103	Missense	distal	6	no	77.022	78.640	EPSD	ICGC;COSMIC	72.838	Up-regulation
CMGC_GSK_GSK3A_ST	P49840	GSK3A	P49840	GSK3A	S282	R286Q	286	Missense	distal	4	no	74.809	70.190	EPSD	ICGC;COSMIC	72.838	Loss
CMGC_GSK_GSK3A_ST	P22415	USF1	P49840	GSK3A	S186	S186Y	186	Missense	central	0	yes	92.592	0.000	PhosphoSitePlus;EPSD	ICGC;COSMIC	72.838	Loss
CMGC_GSK_GSK3A_ST	P22415	USF1	P49840	GSK3A	S186	S186F	186	Missense	central	0	yes	92.592	0.000	PhosphoSitePlus;EPSD	ICGC	72.838	Loss
CMGC_GSK_GSK3A_ST	Q96F46	IL17RA	P49840	GSK3A	T732	P737A	737	Missense	distal	5	no	80.376	73.900	EPSD	ICGC;COSMIC	72.838	Down-regulation
CMGC_GSK_GSK3A_ST	Q96F46	IL17RA	P49840	GSK3A	T732	A735S	735	Missense	distal	3	no	80.376	79.733	EPSD	ICGC	72.838	Down-regulation
CMGC_GSK_GSK3A_ST	Q96F46	IL17RA	P49840	GSK3A	S736	P737A	737	Missense	proximal	1	no	74.091	60.424	EPSD	ICGC;COSMIC	72.838	Loss
CMGC_GSK_GSK3A_ST	Q96F46	IL17RA	P49840	GSK3A	S736	A735S	735	Missense	proximal	-1	no	74.091	73.318	EPSD	ICGC	72.838	Down-regulation
CMGC_GSK_GSK3A_ST	Q96F46	IL17RA	P49840	GSK3A	T780	T780M	780	Missense	central	0	yes	90.191	0.000	PhosphoSitePlus	ICGC;COSMIC	72.838	Loss
CMGC_GSK_GSK3A_ST	Q96F46	IL17RA	P49840	GSK3A	T780	R787W	787	Missense	distal	7	no	90.191	90.189	PhosphoSitePlus	ICGC	72.838	Down-regulation
CMGC_GSK_GSK3A_ST	Q96F46	IL17RA	P49840	GSK3A	S801	S798F	798	Missense	distal	-3	no	81.014	79.785	EPSD	ICGC	72.838	Down-regulation
CMGC_GSK_GSK3A_ST	Q96F46	IL17RA	P49840	GSK3A	S829	P824S	824	Missense	distal	-5	no	79.854	79.941	EPSD	ICGC;COSMIC	72.838	Up-regulation
CMGC_GSK_GSK3A_ST	P17661	DES	P49840	GSK3A	S28	P22L	22	Missense	distal	-6	no	88.351	88.477	EPSD;PhosphoSitePlus	ICGC;COSMIC	72.838	Up-regulation
CMGC_GSK_GSK3A_ST	P17661	DES	P49840	GSK3A	S28	G27V	27	Missense	proximal	-1	no	88.351	88.608	EPSD;PhosphoSitePlus	ICGC;COSMIC	72.838	Up-regulation
CMGC_GSK_GSK3A_ST	P17661	DES	P49840	GSK3A	S28	P29Q	29	Missense	proximal	1	no	88.351	77.674	EPSD;PhosphoSitePlus	ICGC;COSMIC	72.838	Down-regulation
CMGC_GSK_GSK3A_ST	P17661	DES	P49840	GSK3A	S32	G27V	27	Missense	distal	-5	no	86.250	85.650	PhosphoSitePlus;EPSD	ICGC;COSMIC	72.838	Down-regulation
CMGC_GSK_GSK3A_ST	P17661	DES	P49840	GSK3A	S32	R37L	37	Missense	distal	5	no	86.250	82.221	PhosphoSitePlus;EPSD	ICGC;COSMIC	72.838	Down-regulation
CMGC_GSK_GSK3A_ST	P17661	DES	P49840	GSK3A	S32	P29Q	29	Missense	distal	-3	no	86.250	85.008	PhosphoSitePlus;EPSD	ICGC;COSMIC	72.838	Down-regulation
CMGC_GSK_GSK3A_ST	P17661	DES	P49840	GSK3A	S32	P36L	36	Missense	distal	4	no	86.250	86.826	PhosphoSitePlus;EPSD	ICGC;COSMIC	72.838	Up-regulation
CMGC_GSK_GSK3A_ST	P17661	DES	P49840	GSK3A	S46	V53M	53	Missense	distal	7	no	72.830	73.070	EPSD	ICGC;COSMIC	72.838	Gain
CMGC_GSK_GSK3A_ST	P17661	DES	P49840	GSK3A	S46	R52H	52	Missense	distal	6	no	72.830	74.310	EPSD	ICGC;COSMIC	72.838	Gain
CMGC_GSK_GSK3A_ST	P35222	CTNNB1	P49840	GSK3A	S246	L252H	252	Missense	distal	6	no	78.466	83.683	EPSD	ICGC;COSMIC	72.838	Up-regulation
CMGC_GSK_GSK3A_ST	P35222	CTNNB1	P49840	GSK3A	T547	R542C	542	Missense	distal	-5	no	77.744	77.061	EPSD	ICGC;COSMIC	72.838	Down-regulation
CMGC_GSK_GSK3A_ST	Q9Y6Q9	NCOA3	P49840	GSK3A	S230	C226W	226	Missense	distal	-4	no	61.451	76.550	EPSD	ICGC;COSMIC	72.838	Gain
CMGC_GSK_GSK3A_ST	Q9Y6Q9	NCOA3	P49840	GSK3A	S284	D281Y	281	Missense	distal	-3	no	78.673	80.162	EPSD	ICGC;COSMIC	72.838	Up-regulation
CMGC_GSK_GSK3A_ST	Q9Y6Q9	NCOA3	P49840	GSK3A	S413	M411T	411	Missense	proximal	-2	no	73.868	74.332	EPSD	ICGC;COSMIC	72.838	Up-regulation
CMGC_GSK_GSK3A_ST	Q9Y6Q9	NCOA3	P49840	GSK3A	S413	G418V	418	Missense	distal	5	no	73.868	71.369	EPSD	ICGC	72.838	Loss
CMGC_GSK_GSK3A_ST	Q9Y6Q9	NCOA3	P49840	GSK3A	T425	S423N	423	Missense	proximal	-2	no	81.714	80.829	EPSD	ICGC;COSMIC	72.838	Down-regulation
CMGC_GSK_GSK3A_ST	Q9Y6Q9	NCOA3	P49840	GSK3A	T425	G418V	418	Missense	distal	-7	no	81.714	81.604	EPSD	ICGC	72.838	Down-regulation
CMGC_GSK_GSK3A_ST	Q9Y6Q9	NCOA3	P49840	GSK3A	T425	G426V	426	Missense	proximal	1	no	81.714	68.700	EPSD	ICGC	72.838	Loss
CMGC_GSK_GSK3A_ST	Q9Y6Q9	NCOA3	P49840	GSK3A	T425	A431T	431	Missense	distal	6	no	81.714	84.440	EPSD	ICGC;COSMIC	72.838	Up-regulation
CMGC_GSK_GSK3A_ST	Q9Y6Q9	NCOA3	P49840	GSK3A	S429	S423N	423	Missense	distal	-6	no	77.632	78.220	EPSD	ICGC;COSMIC	72.838	Up-regulation
CMGC_GSK_GSK3A_ST	Q9Y6Q9	NCOA3	P49840	GSK3A	S429	G426V	426	Missense	distal	-3	no	77.632	78.182	EPSD	ICGC	72.838	Up-regulation
CMGC_GSK_GSK3A_ST	Q9Y6Q9	NCOA3	P49840	GSK3A	S429	A431T	431	Missense	proximal	2	no	77.632	79.307	EPSD	ICGC;COSMIC	72.838	Up-regulation
CMGC_GSK_GSK3A_ST	Q9Y6Q9	NCOA3	P49840	GSK3A	S464	H468L	468	Missense	distal	4	no	53.174	75.802	EPSD	ICGC;COSMIC	72.838	Gain
CMGC_GSK_GSK3A_ST	Q9Y6Q9	NCOA3	P49840	GSK3A	S465	H468L	468	Missense	distal	3	no	78.023	71.198	EPSD	ICGC;COSMIC	72.838	Loss
CMGC_GSK_GSK3A_ST	Q9Y6Q9	NCOA3	P49840	GSK3A	S470	H468L	468	Missense	proximal	-2	no	88.413	87.798	EPSD	ICGC;COSMIC	72.838	Down-regulation
CMGC_GSK_GSK3A_ST	Q9Y6Q9	NCOA3	P49840	GSK3A	S505	S498F	498	Missense	distal	-7	no	80.489	77.410	EPSD;PhosphoSitePlus	ICGC;COSMIC	72.838	Down-regulation
CMGC_GSK_GSK3A_ST	Q9Y6Q9	NCOA3	P49840	GSK3A	S543	L548W	548	Missense	distal	5	no	82.446	61.413	EPSD	ICGC;COSMIC	72.838	Loss
CMGC_GSK_GSK3A_ST	Q9Y6Q9	NCOA3	P49840	GSK3A	S636	S635F	635	Missense	proximal	-1	no	85.951	83.600	EPSD	ICGC	72.838	Down-regulation
CMGC_GSK_GSK3A_ST	Q9Y6Q9	NCOA3	P49840	GSK3A	S640	S635F	635	Missense	distal	-5	no	93.688	88.321	EPSD	ICGC	72.838	Down-regulation
CMGC_GSK_GSK3A_ST	Q9Y6Q9	NCOA3	P49840	GSK3A	S694	A696T	696	Missense	proximal	2	no	83.545	85.220	EPSD	ICGC	72.838	Up-regulation
CMGC_GSK_GSK3A_ST	Q9Y6Q9	NCOA3	P49840	GSK3A	S767	G761V	761	Missense	distal	-6	no	80.745	81.549	EPSD	ICGC;COSMIC	72.838	Up-regulation
CMGC_GSK_GSK3A_ST	Q9Y6Q9	NCOA3	P49840	GSK3A	T912	S917T	917	Missense	distal	5	no	72.944	73.621	EPSD	ICGC;COSMIC	72.838	Up-regulation
CMGC_GSK_GSK3A_ST	Q9Y6Q9	NCOA3	P49840	GSK3A	T912	V911M	911	Missense	proximal	-1	no	72.944	72.776	EPSD	ICGC;COSMIC	72.838	Loss
CMGC_GSK_GSK3A_ST	Q9Y6Q9	NCOA3	P49840	GSK3A	S1330	A1324S	1324	Missense	distal	-6	no	83.229	82.520	EPSD	ICGC	72.838	Down-regulation
CMGC_GSK_GSK3A_ST	P31749	AKT1	P49840	GSK3A	T312	T305N	305	Missense	distal	-7	no	84.746	84.181	EPSD;PhosphoSitePlus	ICGC	72.838	Down-regulation
CMGC_GSK_GSK3A_ST	P31749	AKT1	P49840	GSK3A	S422	K420T	420	Missense	proximal	-2	no	74.281	72.987	EPSD	ICGC	72.838	Down-regulation
CMGC_GSK_GSK3A_ST	P31749	AKT1	P49840	GSK3A	T450	Q454K	454	Missense	distal	4	no	64.090	75.488	EPSD	ICGC	72.838	Gain
CMGC_GSK_GSK3A_ST	Q16584	MAP3K11	P49840	GSK3A	S35	A42D	42	Missense	distal	7	no	84.846	83.296	EPSD	ICGC	72.838	Down-regulation
CMGC_GSK_GSK3A_ST	Q16584	MAP3K11	P49840	GSK3A	S35	P36H	36	Missense	proximal	1	no	84.846	58.432	EPSD	ICGC	72.838	Loss
CMGC_GSK_GSK3A_ST	Q16584	MAP3K11	P49840	GSK3A	S507	R501H	501	Missense	distal	-6	no	83.004	82.779	EPSD	ICGC;COSMIC	72.838	Down-regulation
CMGC_GSK_GSK3A_ST	Q16584	MAP3K11	P49840	GSK3A	S507	P508T	508	Missense	proximal	1	no	83.004	68.352	EPSD	ICGC;COSMIC	72.838	Loss
CMGC_GSK_GSK3A_ST	Q16584	MAP3K11	P49840	GSK3A	S507	L510I	510	Missense	distal	3	no	83.004	84.831	EPSD	ICGC	72.838	Up-regulation
CMGC_GSK_GSK3A_ST	Q16584	MAP3K11	P49840	GSK3A	S548	A543E	543	Missense	distal	-5	no	74.857	73.661	EPSD	ICGC;COSMIC	72.838	Down-regulation
CMGC_GSK_GSK3A_ST	Q16584	MAP3K11	P49840	GSK3A	S674	P675L	675	Missense	proximal	1	no	89.853	75.801	EPSD	ICGC;COSMIC	72.838	Down-regulation
CMGC_GSK_GSK3A_ST	Q16584	MAP3K11	P49840	GSK3A	S674	R671C	671	Missense	distal	-3	no	89.853	89.219	EPSD	ICGC;COSMIC	72.838	Down-regulation
CMGC_GSK_GSK3A_ST	Q16584	MAP3K11	P49840	GSK3A	T677	P675L	675	Missense	proximal	-2	no	82.147	81.280	EPSD	ICGC;COSMIC	72.838	Down-regulation
CMGC_GSK_GSK3A_ST	Q16584	MAP3K11	P49840	GSK3A	T677	R671C	671	Missense	distal	-6	no	82.147	82.355	EPSD	ICGC;COSMIC	72.838	Up-regulation
CMGC_GSK_GSK3A_ST	Q16584	MAP3K11	P49840	GSK3A	T680	P675L	675	Missense	distal	-5	no	93.279	91.716	EPSD	ICGC;COSMIC	72.838	Down-regulation
CMGC_GSK_GSK3A_ST	Q16584	MAP3K11	P49840	GSK3A	S705	L712Q	712	Missense	distal	7	no	79.758	80.349	EPSD	ICGC;COSMIC	72.838	Up-regulation
CMGC_GSK_GSK3A_ST	Q16584	MAP3K11	P49840	GSK3A	T708	L712Q	712	Missense	distal	4	no	82.975	74.370	EPSD	ICGC;COSMIC	72.838	Down-regulation
CMGC_GSK_GSK3A_ST	Q16584	MAP3K11	P49840	GSK3A	T745	T752A	752	Missense	distal	7	no	79.217	78.828	EPSD	ICGC	72.838	Down-regulation
CMGC_GSK_GSK3A_ST	Q16584	MAP3K11	P49840	GSK3A	T745	G751S	751	Missense	distal	6	no	79.217	80.170	EPSD	ICGC	72.838	Up-regulation
CMGC_GSK_GSK3A_ST	Q16584	MAP3K11	P49840	GSK3A	S746	T752A	752	Missense	distal	6	no	83.571	80.844	EPSD	ICGC	72.838	Down-regulation
CMGC_GSK_GSK3A_ST	Q16584	MAP3K11	P49840	GSK3A	S746	G751S	751	Missense	distal	5	no	83.571	83.604	EPSD	ICGC	72.838	Up-regulation
CMGC_GSK_GSK3A_ST	Q16584	MAP3K11	P49840	GSK3A	S748	T752A	752	Missense	distal	4	no	82.960	80.374	EPSD	ICGC	72.838	Down-regulation
CMGC_GSK_GSK3A_ST	Q16584	MAP3K11	P49840	GSK3A	S748	G751S	751	Missense	distal	3	no	82.960	83.567	EPSD	ICGC	72.838	Up-regulation
CMGC_GSK_GSK3A_ST	Q16584	MAP3K11	P49840	GSK3A	T752	T752A	752	Missense	central	0	yes	83.041	0.000	EPSD	ICGC	72.838	Loss
CMGC_GSK_GSK3A_ST	Q16584	MAP3K11	P49840	GSK3A	T752	G751S	751	Missense	proximal	-1	no	83.041	83.066	EPSD	ICGC	72.838	Up-regulation
CMGC_GSK_GSK3A_ST	Q16584	MAP3K11	P49840	GSK3A	T755	T752A	752	Missense	distal	-3	no	84.778	83.951	EPSD	ICGC	72.838	Down-regulation
CMGC_GSK_GSK3A_ST	Q16584	MAP3K11	P49840	GSK3A	T755	G751S	751	Missense	distal	-4	no	84.778	89.615	EPSD	ICGC	72.838	Up-regulation
CMGC_GSK_GSK3A_ST	Q16584	MAP3K11	P49840	GSK3A	S783	G785R	785	Missense	proximal	2	no	80.056	81.691	EPSD	ICGC	72.838	Up-regulation
CMGC_GSK_GSK3A_ST	Q16584	MAP3K11	P49840	GSK3A	S789	G785R	785	Missense	distal	-4	no	103.622	105.091	PhosphoSitePlus;EPSD	ICGC	72.838	Up-regulation
CMGC_GSK_GSK3A_ST	Q16584	MAP3K11	P49840	GSK3A	S789	P796T	796	Missense	distal	7	no	103.622	103.868	PhosphoSitePlus;EPSD	ICGC;COSMIC	72.838	Up-regulation
CMGC_GSK_GSK3A_ST	Q16584	MAP3K11	P49840	GSK3A	S793	P796T	796	Missense	distal	3	no	89.990	90.680	EPSD;PhosphoSitePlus	ICGC;COSMIC	72.838	Up-regulation
CMGC_GSK_GSK3A_ST	Q16584	MAP3K11	P49840	GSK3A	S793	R799S	799	Missense	distal	6	no	89.990	88.584	EPSD;PhosphoSitePlus	ICGC;COSMIC	72.838	Down-regulation
CMGC_GSK_GSK3A_ST	O75030	MITF	P49840	GSK3A	S55	R60C	60	Missense	distal	5	no	75.212	61.518	EPSD	ICGC;COSMIC	72.838	Loss
CMGC_GSK_GSK3A_ST	O75030	MITF	P49840	GSK3A	S405	L404F	404	Missense	proximal	-1	no	82.930	80.836	EPSD	ICGC	72.838	Down-regulation
CMGC_GSK_GSK3A_ST	O75030	MITF	P49840	GSK3A	S405	L404P	404	Missense	proximal	-1	no	82.930	84.085	EPSD	ICGC;COSMIC	72.838	Up-regulation
CMGC_GSK_GSK3A_ST	O75030	MITF	P49840	GSK3A	S405	R400Q	400	Missense	distal	-5	no	82.930	85.279	EPSD	ICGC;COSMIC	72.838	Up-regulation
CMGC_GSK_GSK3A_ST	O75030	MITF	P49840	GSK3A	S491	G494D	494	Missense	distal	3	no	78.972	81.450	EPSD	ICGC;COSMIC	72.838	Up-regulation
CMGC_GSK_GSK3A_ST	O75030	MITF	P49840	GSK3A	S491	D488N	488	Missense	distal	-3	no	78.972	78.759	EPSD	ICGC;COSMIC	72.838	Down-regulation
CMGC_GSK_GSK3A_ST	O75030	MITF	P49840	GSK3A	S491	T496N	496	Missense	distal	5	no	78.972	56.528	EPSD	ICGC;COSMIC	72.838	Loss
CMGC_GSK_GSK3A_ST	O75030	MITF	P49840	GSK3A	S491	D488G	488	Missense	distal	-3	no	78.972	79.182	EPSD	ICGC	72.838	Up-regulation
CMGC_GSK_GSK3A_ST	O75030	MITF	P49840	GSK3A	S491	L490F	490	Missense	proximal	-1	no	78.972	76.879	EPSD	ICGC;COSMIC	72.838	Down-regulation
CMGC_GSK_GSK3A_ST	O75030	MITF	P49840	GSK3A	S491	D497G	497	Missense	distal	6	no	78.972	78.257	EPSD	ICGC;COSMIC	72.838	Down-regulation
CMGC_GSK_GSK3A_ST	O75030	MITF	P49840	GSK3A	S504	G506R	506	Missense	proximal	2	no	80.561	82.196	EPSD	ICGC;COSMIC	72.838	Up-regulation
CMGC_GSK_GSK3A_ST	O75030	MITF	P49840	GSK3A	S504	S504C	504	Missense	central	0	yes	80.561	0.000	EPSD	ICGC;COSMIC	72.838	Loss
CMGC_GSK_GSK3A_ST	O75030	MITF	P49840	GSK3A	S504	S504P	504	Missense	central	0	yes	80.561	0.000	EPSD	ICGC	72.838	Loss
CMGC_GSK_GSK3A_ST	O75030	MITF	P49840	GSK3A	S504	D497G	497	Missense	distal	-7	no	80.561	82.172	EPSD	ICGC;COSMIC	72.838	Up-regulation
CMGC_GSK_GSK3A_ST	O75030	MITF	P49840	GSK3A	S504	L500F	500	Missense	distal	-4	no	80.561	79.077	EPSD	ICGC;COSMIC	72.838	Down-regulation
CMGC_GSK_GSK3A_ST	O75030	MITF	P49840	GSK3A	S508	G506R	506	Missense	proximal	-2	no	81.179	82.282	EPSD	ICGC;COSMIC	72.838	Up-regulation
CMGC_GSK_GSK3A_ST	O75030	MITF	P49840	GSK3A	S508	S504C	504	Missense	distal	-4	no	81.179	57.101	EPSD	ICGC;COSMIC	72.838	Loss
CMGC_GSK_GSK3A_ST	O75030	MITF	P49840	GSK3A	S508	S504P	504	Missense	distal	-4	no	81.179	77.592	EPSD	ICGC	72.838	Down-regulation
CMGC_GSK_GSK3A_ST	O75030	MITF	P49840	GSK3A	S508	R513Q	513	Missense	distal	5	no	81.179	75.924	EPSD	ICGC;COSMIC	72.838	Down-regulation
CMGC_GSK_GSK3A_ST	P24864	CCNE1	P49840	GSK3A	S103	P106H	106	Missense	distal	3	no	79.511	82.476	EPSD	ICGC;COSMIC	72.838	Up-regulation
CMGC_GSK_GSK3A_ST	P24864	CCNE1	P49840	GSK3A	S103	V107A	107	Missense	distal	4	no	79.511	82.005	EPSD	ICGC;COSMIC	72.838	Up-regulation
CMGC_GSK_GSK3A_ST	P24864	CCNE1	P49840	GSK3A	S387	L394I	394	Missense	distal	7	no	74.609	75.126	EPSD	ICGC	72.838	Up-regulation
CMGC_GSK_GSK3A_ST	P24864	CCNE1	P49840	GSK3A	S391	L394I	394	Missense	distal	3	no	89.096	90.923	EPSD	ICGC	72.838	Up-regulation
CMGC_GSK_GSK3A_ST	P24864	CCNE1	P49840	GSK3A	T395	S399I	399	Missense	distal	4	no	86.429	82.355	PhosphoSitePlus	ICGC;COSMIC	72.838	Down-regulation
CMGC_GSK_GSK3A_ST	P24864	CCNE1	P49840	GSK3A	T395	S399R	399	Missense	distal	4	no	86.429	77.033	PhosphoSitePlus	ICGC;COSMIC;GDSC;CCLE	72.838	Down-regulation
CMGC_GSK_GSK3A_ST	P24864	CCNE1	P49840	GSK3A	T395	G400D	400	Missense	distal	5	no	86.429	85.150	PhosphoSitePlus	ICGC;COSMIC	72.838	Down-regulation
CMGC_GSK_GSK3A_ST	P24864	CCNE1	P49840	GSK3A	T395	L394I	394	Missense	proximal	-1	no	86.429	85.471	PhosphoSitePlus	ICGC	72.838	Down-regulation
CMGC_GSK_GSK3A_ST	Q6R327	RICTOR	P49840	GSK3A	S265	Q272K	272	Missense	distal	7	no	76.825	77.480	EPSD	ICGC;COSMIC	72.838	Up-regulation
CMGC_GSK_GSK3A_ST	Q6R327	RICTOR	P49840	GSK3A	S265	P266Q	266	Missense	proximal	1	no	76.825	66.149	EPSD	ICGC;COSMIC	72.838	Loss
CMGC_GSK_GSK3A_ST	Q6R327	RICTOR	P49840	GSK3A	S1030	S1031C	1031	Missense	proximal	1	no	85.491	74.142	EPSD	ICGC;COSMIC;GDSC;CCLE	72.838	Down-regulation
CMGC_GSK_GSK3A_ST	Q6R327	RICTOR	P49840	GSK3A	S1031	S1031C	1031	Missense	central	0	yes	85.403	0.000	EPSD	ICGC;COSMIC;GDSC;CCLE	72.838	Loss
CMGC_GSK_GSK3A_ST	Q6R327	RICTOR	P49840	GSK3A	S1035	S1031C	1031	Missense	distal	-4	no	73.166	49.088	EPSD	ICGC;COSMIC;GDSC;CCLE	72.838	Loss
CMGC_GSK_GSK3A_ST	Q6R327	RICTOR	P49840	GSK3A	S1121	P1115S	1115	Missense	distal	-6	no	73.112	73.058	EPSD	ICGC	72.838	Down-regulation
CMGC_GSK_GSK3A_ST	Q6R327	RICTOR	P49840	GSK3A	T1148	T1148K	1148	Missense	central	0	yes	83.010	0.000	EPSD	ICGC	72.838	Loss
CMGC_GSK_GSK3A_ST	Q6R327	RICTOR	P49840	GSK3A	T1148	H1143Y	1143	Missense	distal	-5	no	83.010	83.318	EPSD	ICGC	72.838	Up-regulation
CMGC_GSK_GSK3A_ST	Q6R327	RICTOR	P49840	GSK3A	T1198	V1204I	1204	Missense	distal	6	no	72.028	73.945	EPSD	ICGC;COSMIC	72.838	Gain
CMGC_GSK_GSK3A_ST	Q6R327	RICTOR	P49840	GSK3A	S1217	R1216C	1216	Missense	proximal	-1	no	73.728	73.061	EPSD	ICGC;COSMIC	72.838	Down-regulation
CMGC_GSK_GSK3A_ST	Q6R327	RICTOR	P49840	GSK3A	S1219	R1216C	1216	Missense	distal	-3	no	82.371	81.737	EPSD	ICGC;COSMIC	72.838	Down-regulation
CMGC_GSK_GSK3A_ST	Q6R327	RICTOR	P49840	GSK3A	T1222	R1216C	1216	Missense	distal	-6	no	75.301	75.509	EPSD	ICGC;COSMIC	72.838	Up-regulation
CMGC_GSK_GSK3A_ST	Q6R327	RICTOR	P49840	GSK3A	T1226	M1232V	1232	Missense	distal	6	no	75.950	73.004	EPSD	ICGC;COSMIC	72.838	Down-regulation
CMGC_GSK_GSK3A_ST	Q6R327	RICTOR	P49840	GSK3A	T1226	S1230T	1230	Missense	distal	4	no	75.950	75.450	EPSD	ICGC	72.838	Down-regulation
CMGC_GSK_GSK3A_ST	Q6R327	RICTOR	P49840	GSK3A	S1230	M1232V	1232	Missense	proximal	2	no	77.524	76.258	EPSD	ICGC;COSMIC	72.838	Down-regulation
CMGC_GSK_GSK3A_ST	Q6R327	RICTOR	P49840	GSK3A	S1233	M1232V	1232	Missense	proximal	-1	no	84.187	84.355	EPSD	ICGC;COSMIC	72.838	Up-regulation
CMGC_GSK_GSK3A_ST	Q6R327	RICTOR	P49840	GSK3A	S1233	S1230T	1230	Missense	distal	-3	no	84.187	85.339	EPSD	ICGC	72.838	Up-regulation
CMGC_GSK_GSK3A_ST	Q6R327	RICTOR	P49840	GSK3A	S1235	M1232V	1232	Missense	distal	-3	no	93.197	93.245	EPSD	ICGC;COSMIC	72.838	Up-regulation
CMGC_GSK_GSK3A_ST	Q6R327	RICTOR	P49840	GSK3A	S1235	S1230T	1230	Missense	distal	-5	no	93.197	92.870	EPSD	ICGC	72.838	Down-regulation
CMGC_GSK_GSK3A_ST	Q6R327	RICTOR	P49840	GSK3A	S1237	M1232V	1232	Missense	distal	-5	no	73.549	75.061	EPSD	ICGC;COSMIC	72.838	Up-regulation
CMGC_GSK_GSK3A_ST	Q6R327	RICTOR	P49840	GSK3A	S1237	S1230T	1230	Missense	distal	-7	no	73.549	74.397	EPSD	ICGC	72.838	Up-regulation
CMGC_GSK_GSK3A_ST	Q6R327	RICTOR	P49840	GSK3A	T1271	H1276R	1276	Missense	distal	5	no	73.872	80.367	EPSD	ICGC;COSMIC	72.838	Up-regulation
CMGC_GSK_GSK3A_ST	Q6R327	RICTOR	P49840	GSK3A	T1271	Q1273K	1273	Missense	proximal	2	no	73.872	75.792	EPSD	ICGC;COSMIC	72.838	Up-regulation
CMGC_GSK_GSK3A_ST	Q6R327	RICTOR	P49840	GSK3A	S1280	H1276R	1276	Missense	distal	-4	no	75.233	72.268	EPSD	ICGC;COSMIC	72.838	Loss
CMGC_GSK_GSK3A_ST	Q6R327	RICTOR	P49840	GSK3A	S1280	Q1273K	1273	Missense	distal	-7	no	75.233	76.592	EPSD	ICGC;COSMIC	72.838	Up-regulation
CMGC_GSK_GSK3A_ST	Q6R327	RICTOR	P49840	GSK3A	S1286	P1290A	1290	Missense	distal	4	no	83.909	86.809	EPSD	ICGC;COSMIC	72.838	Up-regulation
CMGC_GSK_GSK3A_ST	Q6R327	RICTOR	P49840	GSK3A	S1292	L1296P	1296	Missense	distal	4	no	74.101	73.525	EPSD	ICGC;COSMIC	72.838	Down-regulation
CMGC_GSK_GSK3A_ST	Q6R327	RICTOR	P49840	GSK3A	S1292	P1290A	1290	Missense	proximal	-2	no	74.101	73.648	EPSD	ICGC;COSMIC	72.838	Down-regulation
CMGC_GSK_GSK3A_ST	Q6R327	RICTOR	P49840	GSK3A	T1295	L1296P	1296	Missense	proximal	1	no	63.572	77.624	EPSD	ICGC;COSMIC	72.838	Gain
CMGC_GSK_GSK3A_ST	Q6R327	RICTOR	P49840	GSK3A	S1320	R1325T	1325	Missense	distal	5	no	91.495	91.759	EPSD	ICGC;COSMIC	72.838	Up-regulation
CMGC_GSK_GSK3A_ST	Q6R327	RICTOR	P49840	GSK3A	S1320	R1325K	1325	Missense	distal	5	no	91.495	87.151	EPSD	ICGC	72.838	Down-regulation
CMGC_GSK_GSK3A_ST	Q6R327	RICTOR	P49840	GSK3A	S1323	R1325T	1325	Missense	proximal	2	no	77.631	78.839	EPSD	ICGC;COSMIC	72.838	Up-regulation
CMGC_GSK_GSK3A_ST	Q6R327	RICTOR	P49840	GSK3A	S1323	R1325K	1325	Missense	proximal	2	no	77.631	78.952	EPSD	ICGC	72.838	Up-regulation
CMGC_GSK_GSK3A_ST	Q6R327	RICTOR	P49840	GSK3A	S1353	S1348C	1348	Missense	distal	-5	no	76.756	74.399	EPSD	ICGC;COSMIC	72.838	Down-regulation
CMGC_GSK_GSK3A_ST	Q6R327	RICTOR	P49840	GSK3A	S1353	S1353Y	1353	Missense	central	0	yes	76.756	0.000	EPSD	ICGC	72.838	Loss
CMGC_GSK_GSK3A_ST	Q6R327	RICTOR	P49840	GSK3A	S1373	T1376A	1376	Missense	distal	3	no	83.132	81.752	EPSD	ICGC;COSMIC	72.838	Down-regulation
CMGC_GSK_GSK3A_ST	Q6R327	RICTOR	P49840	GSK3A	S1373	S1373F	1373	Missense	central	0	yes	83.132	0.000	EPSD	ICGC;COSMIC	72.838	Loss
CMGC_GSK_GSK3A_ST	Q6R327	RICTOR	P49840	GSK3A	S1581	S1588N	1588	Missense	distal	7	no	74.501	73.852	EPSD	ICGC	72.838	Down-regulation
CMGC_GSK_GSK3A_ST	Q6R327	RICTOR	P49840	GSK3A	S1581	S1581Y	1581	Missense	central	0	yes	74.501	0.000	EPSD	ICGC;COSMIC	72.838	Loss
CMGC_GSK_GSK3A_ST	Q6R327	RICTOR	P49840	GSK3A	T1589	S1588N	1588	Missense	proximal	-1	no	73.203	72.615	EPSD	ICGC	72.838	Loss
CMGC_GSK_GSK3A_ST	P01106	MYC	P49840	GSK3A	S67	P72S	72	Missense	distal	5	no	91.781	86.224	EPSD	ICGC;COSMIC;GDSC	72.838	Down-regulation
CMGC_GSK_GSK3A_ST	P01106	MYC	P49840	GSK3A	S67	P72A	72	Missense	distal	5	no	91.781	85.305	EPSD	ICGC;COSMIC	72.838	Down-regulation
CMGC_GSK_GSK3A_ST	P01106	MYC	P49840	GSK3A	S67	P72L	72	Missense	distal	5	no	91.781	82.608	EPSD	ICGC;COSMIC	72.838	Down-regulation
CMGC_GSK_GSK3A_ST	P01106	MYC	P49840	GSK3A	S67	P72T	72	Missense	distal	5	no	91.781	86.901	EPSD	ICGC;COSMIC;GDSC	72.838	Down-regulation
CMGC_GSK_GSK3A_ST	P01106	MYC	P49840	GSK3A	S71	P72S	72	Missense	proximal	1	no	88.696	73.004	EPSD	ICGC;COSMIC;GDSC	72.838	Down-regulation
CMGC_GSK_GSK3A_ST	P01106	MYC	P49840	GSK3A	S71	P72A	72	Missense	proximal	1	no	88.696	75.029	EPSD	ICGC;COSMIC	72.838	Down-regulation
CMGC_GSK_GSK3A_ST	P01106	MYC	P49840	GSK3A	S71	P72L	72	Missense	proximal	1	no	88.696	74.645	EPSD	ICGC;COSMIC	72.838	Down-regulation
CMGC_GSK_GSK3A_ST	P01106	MYC	P49840	GSK3A	S71	P72T	72	Missense	proximal	1	no	88.696	74.045	EPSD	ICGC;COSMIC;GDSC	72.838	Down-regulation
CMGC_GSK_GSK3A_ST	P01106	MYC	P49840	GSK3A	T78	P72S	72	Missense	distal	-6	no	75.225	75.171	EPSD	ICGC;COSMIC;GDSC	72.838	Down-regulation
CMGC_GSK_GSK3A_ST	P01106	MYC	P49840	GSK3A	T78	P72A	72	Missense	distal	-6	no	75.225	75.881	EPSD	ICGC;COSMIC	72.838	Up-regulation
CMGC_GSK_GSK3A_ST	P01106	MYC	P49840	GSK3A	T78	P72L	72	Missense	distal	-6	no	75.225	75.351	EPSD	ICGC;COSMIC	72.838	Up-regulation
CMGC_GSK_GSK3A_ST	P01106	MYC	P49840	GSK3A	T78	P72T	72	Missense	distal	-6	no	75.225	75.298	EPSD	ICGC;COSMIC;GDSC	72.838	Up-regulation
CMGC_GSK_GSK3A_ST	P01106	MYC	P49840	GSK3A	S373	Q380K	380	Missense	distal	7	no	75.713	76.368	EPSD	ICGC;COSMIC	72.838	Up-regulation
CMGC_GSK_GSK3A_ST	P17812	CTPS1	P49840	GSK3A	S311	F310L	310	Missense	proximal	-1	no	77.066	79.159	EPSD	ICGC;COSMIC	72.838	Up-regulation
CMGC_GSK_GSK3A_ST	P17812	CTPS1	P49840	GSK3A	T459	K460N	460	Missense	proximal	1	no	73.104	19.573	EPSD	ICGC;CCLE	72.838	Loss
CMGC_GSK_GSK3A_ST	P17812	CTPS1	P49840	GSK3A	T459	Q458K	458	Missense	proximal	-1	no	73.104	71.271	EPSD	ICGC;COSMIC	72.838	Loss
CMGC_GSK_GSK3A_ST	P17812	CTPS1	P49840	GSK3A	T459	Q458H	458	Missense	proximal	-1	no	73.104	72.379	EPSD	ICGC;COSMIC	72.838	Loss
CMGC_GSK_GSK3A_ST	P17812	CTPS1	P49840	GSK3A	T459	Q458R	458	Missense	proximal	-1	no	73.104	71.931	EPSD	ICGC;COSMIC	72.838	Loss
CMGC_GSK_GSK3A_ST	P17812	CTPS1	P49840	GSK3A	S562	D565N	565	Missense	distal	3	no	85.728	86.541	EPSD	ICGC	72.838	Up-regulation
CMGC_GSK_GSK3A_ST	P17812	CTPS1	P49840	GSK3A	S571	D565N	565	Missense	distal	-6	no	81.787	81.125	PhosphoSitePlus	ICGC	72.838	Down-regulation
CMGC_GSK_GSK3A_ST	Q13563	PKD2	P49840	GSK3A	S74	P77S	77	Missense	distal	3	no	83.979	82.646	EPSD	ICGC	72.838	Down-regulation
CMGC_GSK_GSK3A_ST	Q13563	PKD2	P49840	GSK3A	S76	P77S	77	Missense	proximal	1	no	88.748	73.056	PhosphoSitePlus	ICGC	72.838	Down-regulation
CMGC_GSK_GSK3A_ST	Q13563	PKD2	P49840	GSK3A	S151	E158K	158	Missense	distal	7	no	78.088	78.234	EPSD	ICGC;COSMIC	72.838	Up-regulation
CMGC_GSK_GSK3A_ST	Q13563	PKD2	P49840	GSK3A	T260	V262M	262	Missense	proximal	2	no	77.689	78.956	EPSD	ICGC;COSMIC	72.838	Up-regulation
CMGC_GSK_GSK3A_ST	Q13563	PKD2	P49840	GSK3A	S263	V262M	262	Missense	proximal	-1	no	73.973	73.805	EPSD	ICGC;COSMIC	72.838	Down-regulation
CMGC_GSK_GSK3A_ST	Q13563	PKD2	P49840	GSK3A	S794	H793Y	793	Missense	proximal	-1	no	73.531	74.701	EPSD	ICGC;COSMIC	72.838	Up-regulation
CMGC_GSK_GSK3A_ST	Q13563	PKD2	P49840	GSK3A	S802	S804I	804	Missense	proximal	2	no	73.096	70.728	EPSD	ICGC	72.838	Loss
CMGC_GSK_GSK3A_ST	Q13563	PKD2	P49840	GSK3A	S804	S804I	804	Missense	central	0	yes	75.424	0.000	EPSD	ICGC	72.838	Loss
CMGC_GSK_GSK3A_ST	Q13563	PKD2	P49840	GSK3A	S808	S804I	804	Missense	distal	-4	no	78.504	72.720	EPSD	ICGC	72.838	Loss
CMGC_GSK_GSK3A_ST	Q07817	BCL2L1	P49840	GSK3A	S62	P63T	63	Missense	proximal	1	no	89.682	75.031	PhosphoSitePlus	ICGC	72.838	Down-regulation
CMGC_GSK_GSK3A_ST	O15084	ANKRD28	P49840	GSK3A	T528	P529L	529	Missense	proximal	1	no	78.477	64.425	EPSD	ICGC;COSMIC	72.838	Loss
CMGC_GSK_GSK3A_ST	O15084	ANKRD28	P49840	GSK3A	T528	L530I	530	Missense	proximal	2	no	78.477	76.130	EPSD	ICGC	72.838	Down-regulation
CMGC_GSK_GSK3A_ST	O15084	ANKRD28	P49840	GSK3A	S537	L530I	530	Missense	distal	-7	no	74.958	75.837	EPSD	ICGC	72.838	Up-regulation
CMGC_GSK_GSK3A_ST	O15084	ANKRD28	P49840	GSK3A	S1007	T1006N	1006	Missense	proximal	-1	no	83.117	80.847	PhosphoSitePlus	ICGC	72.838	Down-regulation
CMGC_GSK_GSK3A_ST	P13051	UNG	P49840	GSK3A	T60	P62H	62	Missense	proximal	2	no	98.672	97.349	EPSD;PhosphoSitePlus	ICGC;COSMIC	72.838	Down-regulation
CMGC_GSK_GSK3A_ST	P13051	UNG	P49840	GSK3A	T60	P65L	65	Missense	distal	5	no	98.672	89.498	EPSD;PhosphoSitePlus	ICGC;COSMIC	72.838	Down-regulation
CMGC_GSK_GSK3A_ST	P13051	UNG	P49840	GSK3A	S63	P62H	62	Missense	proximal	-1	no	82.301	81.554	EPSD	ICGC;COSMIC	72.838	Down-regulation
CMGC_GSK_GSK3A_ST	P13051	UNG	P49840	GSK3A	S63	P65L	65	Missense	proximal	2	no	82.301	81.592	EPSD	ICGC;COSMIC	72.838	Down-regulation
CMGC_GSK_GSK3A_ST	P13051	UNG	P49840	GSK3A	S64	P62H	62	Missense	proximal	-2	no	94.217	93.964	PhosphoSitePlus;EPSD	ICGC;COSMIC	72.838	Down-regulation
CMGC_GSK_GSK3A_ST	P13051	UNG	P49840	GSK3A	S64	P65L	65	Missense	proximal	1	no	94.217	80.165	PhosphoSitePlus;EPSD	ICGC;COSMIC	72.838	Down-regulation
CMGC_GSK_GSK3A_ST	Q9Y4H4	GPSM3	P49840	GSK3A	S74	E79K	79	Missense	distal	5	no	75.614	71.537	EPSD	ICGC;COSMIC	72.838	Loss
CMGC_GSK_GSK3A_ST	Q9Y4H4	GPSM3	P49840	GSK3A	S74	R75H	75	Missense	proximal	1	no	75.614	57.853	EPSD	ICGC	72.838	Loss
CMGC_GSK_GSK3A_ST	Q9Y4H4	GPSM3	P49840	GSK3A	T86	E79K	79	Missense	distal	-7	no	73.753	74.341	EPSD	ICGC;COSMIC	72.838	Up-regulation
CMGC_GSK_GSK3A_ST	Q9Y4H4	GPSM3	P49840	GSK3A	T86	T83N	83	Missense	distal	-3	no	73.753	71.758	EPSD	ICGC;COSMIC	72.838	Loss
CMGC_GSK_GSK3A_ST	Q16555	DPYSL2	P49840	GSK3A	S304	D310G	310	Missense	distal	6	no	92.097	91.382	EPSD	ICGC;COSMIC	72.838	Down-regulation
CMGC_GSK_GSK3A_ST	Q16555	DPYSL2	P49840	GSK3A	S308	D310G	310	Missense	proximal	2	no	79.042	80.907	EPSD	ICGC;COSMIC	72.838	Up-regulation
CMGC_GSK_GSK3A_ST	Q16555	DPYSL2	P49840	GSK3A	T509	P515L	515	Missense	distal	6	no	92.986	90.106	EPSD	ICGC	72.838	Down-regulation
CMGC_GSK_GSK3A_ST	Q16555	DPYSL2	P49840	GSK3A	T514	P515L	515	Missense	proximal	1	no	86.186	72.134	EPSD	ICGC	72.838	Loss
CMGC_GSK_GSK3A_ST	Q16555	DPYSL2	P49840	GSK3A	S517	P515L	515	Missense	proximal	-2	no	75.267	74.400	EPSD	ICGC	72.838	Down-regulation
CMGC_GSK_GSK3A_ST	Q16555	DPYSL2	P49840	GSK3A	S518	P515L	515	Missense	distal	-3	no	88.263	86.519	PhosphoSitePlus	ICGC	72.838	Down-regulation
CMGC_GSK_GSK3A_ST	Q16555	DPYSL2	P49840	GSK3A	T521	P515L	515	Missense	distal	-6	no	74.940	75.067	EPSD	ICGC	72.838	Up-regulation
Atypical_PDHK_PDHK_PDK2_ST	P29803	PDHA2	Q15119	PDK2	S128	S128Y	128	Missense	central	0	yes	1.535	0.000	EPSD	ICGC	1.129	Loss
Atypical_PDHK_PDHK_PDK2_ST	P29803	PDHA2	Q15119	PDK2	S128	R125L	125	Missense	distal	-3	no	1.535	1.544	EPSD	ICGC;COSMIC	1.129	Up-regulation
Atypical_PDHK_PDHK_PDK2_ST	P29803	PDHA2	Q15119	PDK2	S150	M151I	151	Missense	proximal	1	no	2.111	1.320	EPSD	ICGC;COSMIC;GDSC;CCLE	1.129	Down-regulation
Atypical_PDHK_PDHK_PDK2_ST	P29803	PDHA2	Q15119	PDK2	S150	S150L	150	Missense	central	0	yes	2.111	0.000	EPSD	ICGC	1.129	Loss
Atypical_PDHK_PDHK_PDK2_ST	P29803	PDHA2	Q15119	PDK2	T284	R286C	286	Missense	proximal	2	no	1.160	1.163	EPSD	ICGC;COSMIC	1.129	Up-regulation
Atypical_PDHK_PDHK_PDK2_ST	P29803	PDHA2	Q15119	PDK2	T284	P277R	277	Missense	distal	-7	no	1.160	1.129	EPSD	ICGC;COSMIC	1.129	Down-regulation
Atypical_PDHK_PDHK_PDK2_ST	P29803	PDHA2	Q15119	PDK2	T284	R286S	286	Missense	proximal	2	no	1.160	1.179	EPSD	ICGC;COSMIC	1.129	Up-regulation
Atypical_PDHK_PDHK_PDK2_ST	P29803	PDHA2	Q15119	PDK2	S291	R286C	286	Missense	distal	-5	no	4.883	4.884	EPSD;PhosphoSitePlus	ICGC;COSMIC	1.129	Up-regulation
Atypical_PDHK_PDHK_PDK2_ST	P29803	PDHA2	Q15119	PDK2	S291	R286S	286	Missense	distal	-5	no	4.883	4.877	EPSD;PhosphoSitePlus	ICGC;COSMIC	1.129	Down-regulation
CAMK_TSSK_TSSK4_ST	P16220	CREB1	Q6SA08	TSSK4	S133	D140A	140	Missense	distal	7	no	8.812	8.850	PhosphoSitePlus	ICGC;COSMIC	1.711	Up-regulation
CAMK_TSSK_TSSK4_ST	P16220	CREB1	Q6SA08	TSSK4	S143	D140A	140	Missense	distal	-3	no	2.735	2.731	EPSD	ICGC;COSMIC	1.711	Down-regulation
TK_Met_MET_Y	P09874	PARP1	P08581	MET	Y176	S177N	177	Missense	proximal	1	no	30.180	29.720	EPSD	ICGC;COSMIC	27.257	Down-regulation
TK_Met_MET_Y	P09874	PARP1	P08581	MET	Y176	Q180H	180	Missense	distal	4	no	30.180	29.475	EPSD	ICGC;COSMIC	27.257	Down-regulation
TK_Met_MET_Y	P09874	PARP1	P08581	MET	Y309	T316I	316	Missense	distal	7	no	30.165	29.770	EPSD	ICGC;COSMIC	27.257	Down-regulation
TK_Met_MET_Y	P09874	PARP1	P08581	MET	Y737	H742N	742	Missense	distal	5	no	27.512	28.453	EPSD	ICGC	27.257	Up-regulation
TK_Met_MET_Y	P09874	PARP1	P08581	MET	Y907	N906S	906	Missense	proximal	-1	no	35.103	36.398	PhosphoSitePlus	ICGC;COSMIC	27.257	Up-regulation
TK_Met_MET_Y	P09874	PARP1	P08581	MET	Y907	D914E	914	Missense	distal	7	no	35.103	35.056	PhosphoSitePlus	ICGC	27.257	Down-regulation
TK_Met_MET_Y	P08581	MET	P08581	MET	Y1003	D1002N	1002	Missense	proximal	-1	no	28.602	27.561	EPSD	ICGC;COSMIC	27.257	Down-regulation
TK_Met_MET_Y	P08581	MET	P08581	MET	Y1003	P1008S	1008	Missense	distal	5	no	28.602	28.814	EPSD	ICGC;COSMIC	27.257	Up-regulation
TK_Met_MET_Y	P08581	MET	P08581	MET	Y1003	D1002G	1002	Missense	proximal	-1	no	28.602	25.357	EPSD	ICGC;COSMIC	27.257	Loss
TK_Met_MET_Y	P08581	MET	P08581	MET	Y1003	R1004Q	1004	Missense	proximal	1	no	28.602	29.323	EPSD	ICGC;COSMIC	27.257	Up-regulation
TK_Met_MET_Y	P08581	MET	P08581	MET	Y1003	V996I	996	Missense	distal	-7	no	28.602	28.317	EPSD	ICGC;COSMIC	27.257	Down-regulation
TK_Met_MET_Y	P08581	MET	P08581	MET	Y1230	Y1230H	1230	Missense	central	0	yes	30.919	0.000	EPSD;PhosphoSitePlus	ICGC;COSMIC	27.257	Loss
TK_Met_MET_Y	P08581	MET	P08581	MET	Y1230	Y1230C	1230	Missense	central	0	yes	30.919	0.000	EPSD;PhosphoSitePlus	ICGC;COSMIC	27.257	Loss
TK_Met_MET_Y	P08581	MET	P08581	MET	Y1230	D1228H	1228	Missense	proximal	-2	no	30.919	24.699	EPSD;PhosphoSitePlus	ICGC;COSMIC	27.257	Loss
TK_Met_MET_Y	P08581	MET	P08581	MET	Y1230	S1236R	1236	Missense	distal	6	no	30.919	28.476	EPSD;PhosphoSitePlus	ICGC;COSMIC	27.257	Down-regulation
TK_Met_MET_Y	P08581	MET	P08581	MET	Y1230	Y1235H	1235	Missense	distal	5	no	30.919	32.085	EPSD;PhosphoSitePlus	ICGC;COSMIC	27.257	Up-regulation
TK_Met_MET_Y	P08581	MET	P08581	MET	Y1230	D1228Y	1228	Missense	proximal	-2	no	30.919	22.540	EPSD;PhosphoSitePlus	ICGC	27.257	Loss
TK_Met_MET_Y	P08581	MET	P08581	MET	Y1230	D1228A	1228	Missense	proximal	-2	no	30.919	29.942	EPSD;PhosphoSitePlus	ICGC	27.257	Down-regulation
TK_Met_MET_Y	P08581	MET	P08581	MET	Y1234	Y1230H	1230	Missense	distal	-4	no	47.625	48.381	EPSD;PhosphoSitePlus	ICGC;COSMIC	27.257	Up-regulation
TK_Met_MET_Y	P08581	MET	P08581	MET	Y1234	Y1230C	1230	Missense	distal	-4	no	47.625	47.011	EPSD;PhosphoSitePlus	ICGC;COSMIC	27.257	Down-regulation
TK_Met_MET_Y	P08581	MET	P08581	MET	Y1234	D1228H	1228	Missense	distal	-6	no	47.625	47.900	EPSD;PhosphoSitePlus	ICGC;COSMIC	27.257	Up-regulation
TK_Met_MET_Y	P08581	MET	P08581	MET	Y1234	S1236R	1236	Missense	proximal	2	no	47.625	46.237	EPSD;PhosphoSitePlus	ICGC;COSMIC	27.257	Down-regulation
TK_Met_MET_Y	P08581	MET	P08581	MET	Y1234	H1238L	1238	Missense	distal	4	no	47.625	43.485	EPSD;PhosphoSitePlus	ICGC;COSMIC	27.257	Down-regulation
TK_Met_MET_Y	P08581	MET	P08581	MET	Y1234	Y1235H	1235	Missense	proximal	1	no	47.625	47.901	EPSD;PhosphoSitePlus	ICGC;COSMIC	27.257	Up-regulation
TK_Met_MET_Y	P08581	MET	P08581	MET	Y1234	D1228Y	1228	Missense	distal	-6	no	47.625	48.062	EPSD;PhosphoSitePlus	ICGC	27.257	Up-regulation
TK_Met_MET_Y	P08581	MET	P08581	MET	Y1234	D1228A	1228	Missense	distal	-6	no	47.625	47.679	EPSD;PhosphoSitePlus	ICGC	27.257	Up-regulation
TK_Met_MET_Y	P08581	MET	P08581	MET	Y1235	Y1230H	1230	Missense	distal	-5	no	51.951	52.354	EPSD;PhosphoSitePlus	ICGC;COSMIC	27.257	Up-regulation
TK_Met_MET_Y	P08581	MET	P08581	MET	Y1235	Y1230C	1230	Missense	distal	-5	no	51.951	51.657	EPSD;PhosphoSitePlus	ICGC;COSMIC	27.257	Down-regulation
TK_Met_MET_Y	P08581	MET	P08581	MET	Y1235	D1228H	1228	Missense	distal	-7	no	51.951	50.553	EPSD;PhosphoSitePlus	ICGC;COSMIC	27.257	Down-regulation
TK_Met_MET_Y	P08581	MET	P08581	MET	Y1235	S1236R	1236	Missense	proximal	1	no	51.951	50.199	EPSD;PhosphoSitePlus	ICGC;COSMIC	27.257	Down-regulation
TK_Met_MET_Y	P08581	MET	P08581	MET	Y1235	G1242V	1242	Missense	distal	7	no	51.951	51.910	EPSD;PhosphoSitePlus	ICGC	27.257	Down-regulation
TK_Met_MET_Y	P08581	MET	P08581	MET	Y1235	H1238L	1238	Missense	distal	3	no	51.951	52.823	EPSD;PhosphoSitePlus	ICGC;COSMIC	27.257	Up-regulation
TK_Met_MET_Y	P08581	MET	P08581	MET	Y1235	Y1235H	1235	Missense	central	0	yes	51.951	0.000	EPSD;PhosphoSitePlus	ICGC;COSMIC	27.257	Loss
TK_Met_MET_Y	P08581	MET	P08581	MET	Y1235	D1228Y	1228	Missense	distal	-7	no	51.951	50.214	EPSD;PhosphoSitePlus	ICGC	27.257	Down-regulation
TK_Met_MET_Y	P08581	MET	P08581	MET	Y1235	D1228A	1228	Missense	distal	-7	no	51.951	51.372	EPSD;PhosphoSitePlus	ICGC	27.257	Down-regulation
TK_Met_MET_Y	P08581	MET	P08581	MET	Y1313	L1312V	1312	Missense	proximal	-1	no	31.893	33.125	EPSD	ICGC;COSMIC	27.257	Up-regulation
TK_Met_MET_Y	P08581	MET	P08581	MET	Y1313	E1314G	1314	Missense	proximal	1	no	31.893	28.964	EPSD	ICGC;COSMIC	27.257	Down-regulation
TK_Met_MET_Y	P08581	MET	P08581	MET	Y1313	P1311L	1311	Missense	proximal	-2	no	31.893	22.872	EPSD	ICGC;COSMIC	27.257	Loss
TK_Met_MET_Y	P08581	MET	P08581	MET	Y1349	V1352L	1352	Missense	distal	3	no	45.667	40.983	EPSD;PhosphoSitePlus	ICGC;COSMIC	27.257	Down-regulation
TK_Met_MET_Y	P08581	MET	P08581	MET	Y1349	H1351Y	1351	Missense	proximal	2	no	45.667	45.248	EPSD;PhosphoSitePlus	ICGC;COSMIC	27.257	Down-regulation
TK_Met_MET_Y	P08581	MET	P08581	MET	Y1349	Y1356C	1356	Missense	distal	7	no	45.667	45.606	EPSD;PhosphoSitePlus	ICGC;COSMIC	27.257	Down-regulation
TK_Met_MET_Y	P08581	MET	P08581	MET	Y1356	V1352L	1352	Missense	distal	-4	no	49.989	47.527	PhosphoSitePlus;EPSD	ICGC;COSMIC	27.257	Down-regulation
TK_Met_MET_Y	P08581	MET	P08581	MET	Y1356	H1351Y	1351	Missense	distal	-5	no	49.989	49.586	PhosphoSitePlus;EPSD	ICGC;COSMIC	27.257	Down-regulation
TK_Met_MET_Y	P08581	MET	P08581	MET	Y1356	Y1356C	1356	Missense	central	0	yes	49.989	0.000	PhosphoSitePlus;EPSD	ICGC;COSMIC	27.257	Loss
TK_Met_MET_Y	P35568	IRS1	P08581	MET	Y431	D437Y	437	Missense	distal	6	no	45.192	42.872	EPSD	ICGC;COSMIC	27.257	Down-regulation
TK_Met_MET_Y	P35568	IRS1	P08581	MET	Y551	A557D	557	Missense	distal	6	no	40.727	42.033	EPSD	ICGC	27.257	Up-regulation
TK_Met_MET_Y	P35568	IRS1	P08581	MET	Y632	P634S	634	Missense	proximal	2	no	46.790	46.663	EPSD	ICGC;COSMIC	27.257	Down-regulation
TK_Met_MET_Y	P35568	IRS1	P08581	MET	Y632	Y632C	632	Missense	central	0	yes	46.790	0.000	EPSD	ICGC;COSMIC	27.257	Loss
TK_Met_MET_Y	P35568	IRS1	P08581	MET	Y632	K627N	627	Missense	distal	-5	no	46.790	46.779	EPSD	ICGC;COSMIC	27.257	Down-regulation
TK_Met_MET_Y	P35568	IRS1	P08581	MET	Y662	D658E	658	Missense	distal	-4	no	62.811	62.101	EPSD	ICGC	27.257	Down-regulation
TK_Met_MET_Y	P35568	IRS1	P08581	MET	Y662	P667H	667	Missense	distal	5	no	62.811	60.323	EPSD	ICGC;COSMIC	27.257	Down-regulation
TK_Met_MET_Y	P35568	IRS1	P08581	MET	Y695	K697Q	697	Missense	proximal	2	no	33.992	33.685	EPSD	ICGC;COSMIC	27.257	Down-regulation
TK_Met_MET_Y	P35568	IRS1	P08581	MET	Y695	S691F	691	Missense	distal	-4	no	33.992	27.421	EPSD	ICGC	27.257	Down-regulation
TK_Met_MET_Y	P35568	IRS1	P08581	MET	Y732	L725I	725	Missense	distal	-7	no	36.487	36.928	EPSD	ICGC	27.257	Up-regulation
TK_Met_MET_Y	P35568	IRS1	P08581	MET	Y750	G752S	752	Missense	proximal	2	no	54.834	56.589	EPSD	ICGC;COSMIC	27.257	Up-regulation
TK_Met_MET_Y	P35568	IRS1	P08581	MET	Y750	P746T	746	Missense	distal	-4	no	54.834	53.936	EPSD	ICGC	27.257	Down-regulation
TK_Met_MET_Y	P35568	IRS1	P08581	MET	Y750	P746S	746	Missense	distal	-4	no	54.834	56.088	EPSD	ICGC	27.257	Up-regulation
TK_Met_MET_Y	P35568	IRS1	P08581	MET	Y750	D748N	748	Missense	proximal	-2	no	54.834	48.811	EPSD	ICGC	27.257	Down-regulation
TK_Met_MET_Y	P35568	IRS1	P08581	MET	Y751	G752S	752	Missense	proximal	1	no	26.975	29.599	EPSD	ICGC;COSMIC	27.257	Gain
TK_Met_MET_Y	P35568	IRS1	P08581	MET	Y751	P746S	746	Missense	distal	-5	no	26.975	27.990	EPSD	ICGC	27.257	Gain
TK_Met_MET_Y	P35568	IRS1	P08581	MET	Y941	E939D	939	Missense	proximal	-2	no	35.701	35.511	EPSD	ICGC	27.257	Down-regulation
TK_Met_MET_Y	P35568	IRS1	P08581	MET	Y1001	D1003N	1003	Missense	proximal	2	no	48.998	48.900	EPSD	ICGC;COSMIC	27.257	Down-regulation
TK_Met_MET_Y	Q05397	PTK2	P08581	MET	Y5	D7G	7	Missense	proximal	2	no	33.030	31.846	EPSD;PhosphoSitePlus	ICGC;COSMIC	27.257	Down-regulation
TK_Met_MET_Y	Q05397	PTK2	P08581	MET	Y5	L6V	6	Missense	proximal	1	no	33.030	34.938	EPSD;PhosphoSitePlus	ICGC;COSMIC	27.257	Up-regulation
TK_Met_MET_Y	Q05397	PTK2	P08581	MET	Y194	A187T	187	Missense	distal	-7	no	37.254	36.855	EPSD;PhosphoSitePlus	ICGC;COSMIC	27.257	Down-regulation
TK_Met_MET_Y	Q05397	PTK2	P08581	MET	Y720	P723Q	723	Missense	distal	3	no	38.240	25.258	EPSD	ICGC	27.257	Loss
TK_Met_MET_Y	Q05397	PTK2	P08581	MET	Y720	E727K	727	Missense	distal	7	no	38.240	38.133	EPSD	ICGC;COSMIC	27.257	Down-regulation
TK_Met_MET_Y	Q05397	PTK2	P08581	MET	Y898	S897Y	897	Missense	proximal	-1	no	44.742	41.792	EPSD	ICGC	27.257	Down-regulation
TK_Met_MET_Y	Q05397	PTK2	P08581	MET	Y898	S897N	897	Missense	proximal	-1	no	44.742	43.447	EPSD	ICGC;COSMIC	27.257	Down-regulation
TK_Met_MET_Y	Q05397	PTK2	P08581	MET	Y898	S897C	897	Missense	proximal	-1	no	44.742	41.184	EPSD	ICGC	27.257	Down-regulation
CMGC_DYRK_DYRK1_DYRK1A_ST	P10636	MAPT	Q13627	DYRK1A	S64	P59Q	59	Missense	distal	-5	no	41.642	40.966	EPSD	ICGC	34.163	Down-regulation
CMGC_DYRK_DYRK1_DYRK1A_ST	P10636	MAPT	Q13627	DYRK1A	T111	D116E	116	Missense	distal	5	no	49.672	51.551	EPSD	ICGC;COSMIC	34.163	Up-regulation
CMGC_DYRK_DYRK1_DYRK1A_ST	P10636	MAPT	Q13627	DYRK1A	T167	P160L	160	Missense	distal	-7	no	34.037	35.039	EPSD	ICGC;COSMIC	34.163	Gain
CMGC_DYRK_DYRK1_DYRK1A_ST	P10636	MAPT	Q13627	DYRK1A	S171	R164T	164	Missense	distal	-7	no	40.913	40.719	EPSD	ICGC;COSMIC	34.163	Down-regulation
CMGC_DYRK_DYRK1_DYRK1A_ST	P10636	MAPT	Q13627	DYRK1A	S171	A166T	166	Missense	distal	-5	no	40.913	40.905	EPSD	ICGC	34.163	Down-regulation
CMGC_DYRK_DYRK1_DYRK1A_ST	P10636	MAPT	Q13627	DYRK1A	T173	A166T	166	Missense	distal	-7	no	40.645	40.046	EPSD	ICGC	34.163	Down-regulation
CMGC_DYRK_DYRK1_DYRK1A_ST	P10636	MAPT	Q13627	DYRK1A	S214	G208C	208	Missense	distal	-6	no	45.770	44.953	EPSD	ICGC;COSMIC	34.163	Down-regulation
CMGC_DYRK_DYRK1_DYRK1A_ST	P10636	MAPT	Q13627	DYRK1A	S214	R211S	211	Missense	distal	-3	no	45.770	37.180	EPSD	ICGC;COSMIC	34.163	Down-regulation
CMGC_DYRK_DYRK1_DYRK1A_ST	P10636	MAPT	Q13627	DYRK1A	S214	G213E	213	Missense	proximal	-1	no	45.770	45.263	EPSD	ICGC;COSMIC	34.163	Down-regulation
CMGC_DYRK_DYRK1_DYRK1A_ST	P10636	MAPT	Q13627	DYRK1A	S228	P233H	233	Missense	distal	5	no	47.818	43.660	EPSD	ICGC;COSMIC	34.163	Down-regulation
CMGC_DYRK_DYRK1_DYRK1A_ST	P10636	MAPT	Q13627	DYRK1A	S228	S232F	232	Missense	distal	4	no	47.818	50.469	EPSD	ICGC	34.163	Up-regulation
CMGC_DYRK_DYRK1_DYRK1A_ST	P10636	MAPT	Q13627	DYRK1A	S228	D225N	225	Missense	distal	-3	no	47.818	36.620	EPSD	ICGC	34.163	Down-regulation
CMGC_DYRK_DYRK1_DYRK1A_ST	P10636	MAPT	Q13627	DYRK1A	S228	V224I	224	Missense	distal	-4	no	47.818	47.807	EPSD	ICGC;COSMIC	34.163	Down-regulation
CMGC_DYRK_DYRK1_DYRK1A_ST	P10636	MAPT	Q13627	DYRK1A	S235	P233H	233	Missense	proximal	-2	no	46.531	33.899	EPSD	ICGC;COSMIC	34.163	Loss
CMGC_DYRK_DYRK1_DYRK1A_ST	P10636	MAPT	Q13627	DYRK1A	S235	S232F	232	Missense	distal	-3	no	46.531	27.359	EPSD	ICGC	34.163	Loss
CMGC_DYRK_DYRK1_DYRK1A_ST	P10636	MAPT	Q13627	DYRK1A	S235	P239Q	239	Missense	distal	4	no	46.531	47.833	EPSD	ICGC;COSMIC	34.163	Up-regulation
CMGC_DYRK_DYRK1_DYRK1A_ST	P10636	MAPT	Q13627	DYRK1A	S238	P233H	233	Missense	distal	-5	no	39.382	38.508	EPSD	ICGC;COSMIC	34.163	Down-regulation
CMGC_DYRK_DYRK1_DYRK1A_ST	P10636	MAPT	Q13627	DYRK1A	S238	S232F	232	Missense	distal	-6	no	39.382	37.873	EPSD	ICGC	34.163	Down-regulation
CMGC_DYRK_DYRK1_DYRK1A_ST	P10636	MAPT	Q13627	DYRK1A	S238	P239Q	239	Missense	proximal	1	no	39.382	26.718	EPSD	ICGC;COSMIC	34.163	Loss
CMGC_DYRK_DYRK1_DYRK1A_ST	P10636	MAPT	Q13627	DYRK1A	S428	S427F	427	Missense	proximal	-1	no	43.557	45.545	EPSD	ICGC	34.163	Up-regulation
CMGC_DYRK_DYRK1_DYRK1A_ST	P10636	MAPT	Q13627	DYRK1A	S438	Y441H	441	Missense	distal	3	no	58.880	58.861	EPSD	ICGC;COSMIC	34.163	Down-regulation
CMGC_DYRK_DYRK1_DYRK1A_ST	P10636	MAPT	Q13627	DYRK1A	S516	G521R	521	Missense	distal	5	no	52.447	52.794	EPSD	ICGC;COSMIC	34.163	Up-regulation
CMGC_DYRK_DYRK1_DYRK1A_ST	P10636	MAPT	Q13627	DYRK1A	S519	G521R	521	Missense	proximal	2	no	55.503	55.544	EPSD	ICGC;COSMIC	34.163	Up-regulation
CMGC_DYRK_DYRK1_DYRK1A_ST	P10636	MAPT	Q13627	DYRK1A	T522	G521R	521	Missense	proximal	-1	no	56.470	55.546	EPSD	ICGC;COSMIC	34.163	Down-regulation
CMGC_DYRK_DYRK1_DYRK1A_ST	P49418	AMPH	Q13627	DYRK1A	T34	F39L	39	Missense	distal	5	no	36.276	39.515	EPSD	ICGC;COSMIC	34.163	Up-regulation
CMGC_DYRK_DYRK1_DYRK1A_ST	P49418	AMPH	Q13627	DYRK1A	T34	A31T	31	Missense	distal	-3	no	36.276	33.083	EPSD	ICGC;COSMIC	34.163	Loss
CMGC_DYRK_DYRK1_DYRK1A_ST	P49418	AMPH	Q13627	DYRK1A	T34	E40D	40	Missense	distal	6	no	36.276	36.400	EPSD	ICGC;COSMIC	34.163	Up-regulation
CMGC_DYRK_DYRK1_DYRK1A_ST	P49418	AMPH	Q13627	DYRK1A	T34	E33K	33	Missense	proximal	-1	no	36.276	37.150	EPSD	ICGC;COSMIC	34.163	Up-regulation
CMGC_DYRK_DYRK1_DYRK1A_ST	P49418	AMPH	Q13627	DYRK1A	T34	K27N	27	Missense	distal	-7	no	36.276	37.304	EPSD	ICGC;COSMIC	34.163	Up-regulation
CMGC_DYRK_DYRK1_DYRK1A_ST	P49418	AMPH	Q13627	DYRK1A	T260	T260I	260	Missense	central	0	yes	38.916	0.000	EPSD	ICGC	34.163	Loss
CMGC_DYRK_DYRK1_DYRK1A_ST	P49418	AMPH	Q13627	DYRK1A	T260	R256C	256	Missense	distal	-4	no	38.916	38.890	EPSD	ICGC;COSMIC	34.163	Down-regulation
CMGC_DYRK_DYRK1_DYRK1A_ST	P49418	AMPH	Q13627	DYRK1A	T260	G253C	253	Missense	distal	-7	no	38.916	39.877	EPSD	ICGC;COSMIC	34.163	Up-regulation
CMGC_DYRK_DYRK1_DYRK1A_ST	P49418	AMPH	Q13627	DYRK1A	T260	R256P	256	Missense	distal	-4	no	38.916	38.901	EPSD	ICGC;COSMIC	34.163	Down-regulation
CMGC_DYRK_DYRK1_DYRK1A_ST	P49418	AMPH	Q13627	DYRK1A	T260	P254H	254	Missense	distal	-6	no	38.916	38.716	EPSD	ICGC;COSMIC	34.163	Down-regulation
CMGC_DYRK_DYRK1_DYRK1A_ST	P49418	AMPH	Q13627	DYRK1A	S262	T260I	260	Missense	proximal	-2	no	45.398	41.638	EPSD	ICGC	34.163	Down-regulation
CMGC_DYRK_DYRK1_DYRK1A_ST	P49418	AMPH	Q13627	DYRK1A	S262	P269H	269	Missense	distal	7	no	45.398	46.946	EPSD	ICGC;GDSC;CCLE	34.163	Up-regulation
CMGC_DYRK_DYRK1_DYRK1A_ST	P49418	AMPH	Q13627	DYRK1A	S262	R256C	256	Missense	distal	-6	no	45.398	44.490	EPSD	ICGC;COSMIC	34.163	Down-regulation
CMGC_DYRK_DYRK1_DYRK1A_ST	P49418	AMPH	Q13627	DYRK1A	S262	R256P	256	Missense	distal	-6	no	45.398	44.981	EPSD	ICGC;COSMIC	34.163	Down-regulation
CMGC_DYRK_DYRK1_DYRK1A_ST	P49418	AMPH	Q13627	DYRK1A	S272	P269H	269	Missense	distal	-3	no	34.885	30.915	EPSD	ICGC;GDSC;CCLE	34.163	Loss
CMGC_DYRK_DYRK1_DYRK1A_ST	P49418	AMPH	Q13627	DYRK1A	S272	P271Q	271	Missense	proximal	-1	no	34.885	34.884	EPSD	ICGC;COSMIC	34.163	Down-regulation
CMGC_DYRK_DYRK1_DYRK1A_ST	P49418	AMPH	Q13627	DYRK1A	S285	P288S	288	Missense	distal	3	no	36.285	36.807	EPSD	ICGC;COSMIC	34.163	Up-regulation
CMGC_DYRK_DYRK1_DYRK1A_ST	P49418	AMPH	Q13627	DYRK1A	S285	A289E	289	Missense	distal	4	no	36.285	36.908	EPSD	ICGC	34.163	Up-regulation
CMGC_DYRK_DYRK1_DYRK1A_ST	P49418	AMPH	Q13627	DYRK1A	S293	P288S	288	Missense	distal	-5	no	65.700	64.945	EPSD;PhosphoSitePlus	ICGC;COSMIC	34.163	Down-regulation
CMGC_DYRK_DYRK1_DYRK1A_ST	P49418	AMPH	Q13627	DYRK1A	S293	A289E	289	Missense	distal	-4	no	65.700	65.684	EPSD;PhosphoSitePlus	ICGC	34.163	Down-regulation
CMGC_DYRK_DYRK1_DYRK1A_ST	P49418	AMPH	Q13627	DYRK1A	S295	P288S	288	Missense	distal	-7	no	53.995	53.932	EPSD;PhosphoSitePlus	ICGC;COSMIC	34.163	Down-regulation
CMGC_DYRK_DYRK1_DYRK1A_ST	P49418	AMPH	Q13627	DYRK1A	S295	P301T	301	Missense	distal	6	no	53.995	53.992	EPSD;PhosphoSitePlus	ICGC	34.163	Down-regulation
CMGC_DYRK_DYRK1_DYRK1A_ST	P49418	AMPH	Q13627	DYRK1A	S295	A289E	289	Missense	distal	-6	no	53.995	53.865	EPSD;PhosphoSitePlus	ICGC	34.163	Down-regulation
CMGC_DYRK_DYRK1_DYRK1A_ST	P49418	AMPH	Q13627	DYRK1A	T310	K313N	313	Missense	distal	3	no	53.226	53.138	PhosphoSitePlus;EPSD	ICGC;COSMIC	34.163	Down-regulation
CMGC_DYRK_DYRK1_DYRK1A_ST	P49418	AMPH	Q13627	DYRK1A	T312	E318D	318	Missense	distal	6	no	51.793	51.917	EPSD;PhosphoSitePlus	ICGC;COSMIC	34.163	Up-regulation
CMGC_DYRK_DYRK1_DYRK1A_ST	P49418	AMPH	Q13627	DYRK1A	T312	K313N	313	Missense	proximal	1	no	51.793	-0.689	EPSD;PhosphoSitePlus	ICGC;COSMIC	34.163	Loss
CMGC_DYRK_DYRK1_DYRK1A_ST	P49418	AMPH	Q13627	DYRK1A	T336	T335K	335	Missense	proximal	-1	no	33.209	34.618	EPSD	ICGC	34.163	Gain
CMGC_DYRK_DYRK1_DYRK1A_ST	P49418	AMPH	Q13627	DYRK1A	T336	P343H	343	Missense	distal	7	no	33.209	34.757	EPSD	ICGC;COSMIC	34.163	Gain
CMGC_DYRK_DYRK1_DYRK1A_ST	P49418	AMPH	Q13627	DYRK1A	T445	D451E	451	Missense	distal	6	no	45.689	45.564	EPSD	ICGC	34.163	Down-regulation
CMGC_DYRK_DYRK1_DYRK1A_ST	P49418	AMPH	Q13627	DYRK1A	T445	E439K	439	Missense	distal	-6	no	45.689	45.151	EPSD	ICGC	34.163	Down-regulation
CMGC_DYRK_DYRK1_DYRK1A_ST	P49418	AMPH	Q13627	DYRK1A	T445	L441M	441	Missense	distal	-4	no	45.689	45.665	EPSD	ICGC	34.163	Down-regulation
CMGC_DYRK_DYRK1_DYRK1A_ST	P49418	AMPH	Q13627	DYRK1A	T498	E495D	495	Missense	distal	-3	no	35.201	38.184	EPSD	ICGC;COSMIC	34.163	Up-regulation
CMGC_DYRK_DYRK1_DYRK1A_ST	P49418	AMPH	Q13627	DYRK1A	T498	K496E	496	Missense	proximal	-2	no	35.201	35.446	EPSD	ICGC	34.163	Up-regulation
CMGC_DYRK_DYRK1_DYRK1A_ST	P53805	RCAN1	Q13627	DYRK1A	S167	P168T	168	Missense	proximal	1	no	60.157	37.780	EPSD;PhosphoSitePlus	ICGC	34.163	Down-regulation
CMGC_DYRK_DYRK1_DYRK1A_ST	P24928	POLR2A	Q13627	DYRK1A	T549	R546C	546	Missense	distal	-3	no	45.971	22.466	EPSD	ICGC;COSMIC	34.163	Loss
CMGC_DYRK_DYRK1_DYRK1A_ST	P24928	POLR2A	Q13627	DYRK1A	T857	T850K	850	Missense	distal	-7	no	36.096	36.245	EPSD	ICGC	34.163	Up-regulation
CMGC_DYRK_DYRK1_DYRK1A_ST	P24928	POLR2A	Q13627	DYRK1A	T857	R862W	862	Missense	distal	5	no	36.096	32.294	EPSD	ICGC	34.163	Loss
CMGC_DYRK_DYRK1_DYRK1A_ST	P24928	POLR2A	Q13627	DYRK1A	T857	R862L	862	Missense	distal	5	no	36.096	33.576	EPSD	ICGC	34.163	Loss
CMGC_DYRK_DYRK1_DYRK1A_ST	P24928	POLR2A	Q13627	DYRK1A	T857	Y859N	859	Missense	proximal	2	no	36.096	35.578	EPSD	ICGC	34.163	Down-regulation
CMGC_DYRK_DYRK1_DYRK1A_ST	P24928	POLR2A	Q13627	DYRK1A	T857	T850A	850	Missense	distal	-7	no	36.096	36.695	EPSD	ICGC	34.163	Up-regulation
CMGC_DYRK_DYRK1_DYRK1A_ST	P24928	POLR2A	Q13627	DYRK1A	S1030	A1033S	1033	Missense	distal	3	no	42.977	43.168	EPSD	ICGC	34.163	Up-regulation
CMGC_DYRK_DYRK1_DYRK1A_ST	P24928	POLR2A	Q13627	DYRK1A	S1348	V1355I	1355	Missense	distal	7	no	34.381	34.333	EPSD	ICGC	34.163	Down-regulation
CMGC_DYRK_DYRK1_DYRK1A_ST	P24928	POLR2A	Q13627	DYRK1A	S1348	P1354T	1354	Missense	distal	6	no	34.381	34.379	EPSD	ICGC	34.163	Down-regulation
CMGC_DYRK_DYRK1_DYRK1A_ST	P24928	POLR2A	Q13627	DYRK1A	S1348	D1353Y	1353	Missense	distal	5	no	34.381	30.101	EPSD	ICGC	34.163	Loss
CMGC_DYRK_DYRK1_DYRK1A_ST	P24928	POLR2A	Q13627	DYRK1A	T1424	G1425V	1425	Missense	proximal	1	no	42.528	47.357	EPSD	ICGC	34.163	Up-regulation
CMGC_DYRK_DYRK1_DYRK1A_ST	P24928	POLR2A	Q13627	DYRK1A	S1532	G1529D	1529	Missense	distal	-3	no	38.458	32.297	EPSD	ICGC	34.163	Loss
CMGC_DYRK_DYRK1_DYRK1A_ST	P24928	POLR2A	Q13627	DYRK1A	S1571	W1565C	1565	Missense	distal	-6	no	38.122	37.854	EPSD	ICGC	34.163	Down-regulation
CMGC_DYRK_DYRK1_DYRK1A_ST	P24928	POLR2A	Q13627	DYRK1A	S1571	G1570D	1570	Missense	proximal	-1	no	38.122	38.541	EPSD	ICGC	34.163	Up-regulation
CMGC_DYRK_DYRK1_DYRK1A_ST	P24928	POLR2A	Q13627	DYRK1A	S1574	G1570D	1570	Missense	distal	-4	no	45.919	45.941	EPSD	ICGC	34.163	Up-regulation
CMGC_DYRK_DYRK1_DYRK1A_ST	P24928	POLR2A	Q13627	DYRK1A	S1619	T1625P	1625	Missense	distal	6	no	51.765	51.768	EPSD;PhosphoSitePlus	ICGC	34.163	Up-regulation
CMGC_DYRK_DYRK1_DYRK1A_ST	P24928	POLR2A	Q13627	DYRK1A	S1626	T1625P	1625	Missense	proximal	-1	no	35.541	36.190	EPSD	ICGC	34.163	Up-regulation
CMGC_DYRK_DYRK1_DYRK1A_ST	P24928	POLR2A	Q13627	DYRK1A	S1647	S1644L	1644	Missense	distal	-3	no	36.177	31.412	EPSD	ICGC	34.163	Loss
CMGC_DYRK_DYRK1_DYRK1A_ST	P24928	POLR2A	Q13627	DYRK1A	S1661	S1665P	1665	Missense	distal	4	no	38.237	38.040	EPSD	ICGC	34.163	Down-regulation
CMGC_DYRK_DYRK1_DYRK1A_ST	P24928	POLR2A	Q13627	DYRK1A	S1668	S1665P	1665	Missense	distal	-3	no	37.504	34.732	EPSD	ICGC	34.163	Down-regulation
CMGC_DYRK_DYRK1_DYRK1A_ST	P24928	POLR2A	Q13627	DYRK1A	S1829	A1835T	1835	Missense	distal	6	no	42.632	42.587	EPSD	ICGC	34.163	Down-regulation
CMGC_DYRK_DYRK1_DYRK1A_ST	P24928	POLR2A	Q13627	DYRK1A	S1833	A1835T	1835	Missense	proximal	2	no	42.254	41.693	EPSD	ICGC	34.163	Down-regulation
CMGC_DYRK_DYRK1_DYRK1A_ST	P24928	POLR2A	Q13627	DYRK1A	S1836	A1835T	1835	Missense	proximal	-1	no	42.200	41.498	EPSD	ICGC	34.163	Down-regulation
CMGC_DYRK_DYRK1_DYRK1A_ST	P24928	POLR2A	Q13627	DYRK1A	T1840	A1835T	1835	Missense	distal	-5	no	42.348	42.340	EPSD	ICGC	34.163	Down-regulation
CMGC_DYRK_DYRK1_DYRK1A_ST	P24928	POLR2A	Q13627	DYRK1A	S1843	S1850C	1850	Missense	distal	7	no	33.594	36.350	EPSD	ICGC	34.163	Gain
CMGC_DYRK_DYRK1_DYRK1A_ST	P24928	POLR2A	Q13627	DYRK1A	S1847	S1850C	1850	Missense	distal	3	no	40.415	40.034	EPSD	ICGC	34.163	Down-regulation
CMGC_DYRK_DYRK1_DYRK1A_ST	P24928	POLR2A	Q13627	DYRK1A	S1847	T1854P	1854	Missense	distal	7	no	40.415	39.744	EPSD	ICGC	34.163	Down-regulation
CMGC_DYRK_DYRK1_DYRK1A_ST	P24928	POLR2A	Q13627	DYRK1A	S1850	S1850C	1850	Missense	central	0	yes	44.410	0.000	EPSD	ICGC	34.163	Loss
CMGC_DYRK_DYRK1_DYRK1A_ST	P24928	POLR2A	Q13627	DYRK1A	S1850	T1854P	1854	Missense	distal	4	no	44.410	43.538	EPSD	ICGC	34.163	Down-regulation
CMGC_DYRK_DYRK1_DYRK1A_ST	P24928	POLR2A	Q13627	DYRK1A	T1854	S1861L	1861	Missense	distal	7	no	40.096	42.251	EPSD	ICGC	34.163	Up-regulation
CMGC_DYRK_DYRK1_DYRK1A_ST	P24928	POLR2A	Q13627	DYRK1A	T1854	S1850C	1850	Missense	distal	-4	no	40.096	40.084	EPSD	ICGC	34.163	Down-regulation
CMGC_DYRK_DYRK1_DYRK1A_ST	P24928	POLR2A	Q13627	DYRK1A	T1854	T1854P	1854	Missense	central	0	yes	40.096	0.000	EPSD	ICGC	34.163	Loss
CMGC_DYRK_DYRK1_DYRK1A_ST	P24928	POLR2A	Q13627	DYRK1A	S1857	T1854P	1854	Missense	distal	-3	no	32.277	38.525	EPSD	ICGC	34.163	Gain
CMGC_DYRK_DYRK1_DYRK1A_ST	P24928	POLR2A	Q13627	DYRK1A	S1861	S1861L	1861	Missense	central	0	yes	37.943	0.000	EPSD	ICGC	34.163	Loss
CMGC_DYRK_DYRK1_DYRK1A_ST	P24928	POLR2A	Q13627	DYRK1A	S1861	T1854P	1854	Missense	distal	-7	no	37.943	38.226	EPSD	ICGC	34.163	Up-regulation
CMGC_DYRK_DYRK1_DYRK1A_ST	P24928	POLR2A	Q13627	DYRK1A	S1864	S1861L	1861	Missense	distal	-3	no	45.115	40.350	EPSD	ICGC	34.163	Down-regulation
CMGC_DYRK_DYRK1_DYRK1A_ST	P24928	POLR2A	Q13627	DYRK1A	S1868	S1861L	1861	Missense	distal	-7	no	42.674	43.739	EPSD	ICGC	34.163	Up-regulation
CMGC_DYRK_DYRK1_DYRK1A_ST	P24928	POLR2A	Q13627	DYRK1A	T1885	P1890S	1890	Missense	distal	5	no	43.317	43.378	EPSD	ICGC	34.163	Up-regulation
CMGC_DYRK_DYRK1_DYRK1A_ST	P24928	POLR2A	Q13627	DYRK1A	S1889	P1890S	1890	Missense	proximal	1	no	43.194	21.241	EPSD	ICGC	34.163	Loss
CMGC_DYRK_DYRK1_DYRK1A_ST	P24928	POLR2A	Q13627	DYRK1A	S1892	P1890S	1890	Missense	proximal	-2	no	39.918	34.982	EPSD	ICGC	34.163	Down-regulation
CMGC_DYRK_DYRK1_DYRK1A_ST	P24928	POLR2A	Q13627	DYRK1A	S1896	P1890S	1890	Missense	distal	-6	no	37.561	38.265	EPSD	ICGC	34.163	Up-regulation
CMGC_DYRK_DYRK1_DYRK1A_ST	P24928	POLR2A	Q13627	DYRK1A	S1913	S1920F	1920	Missense	distal	7	no	40.178	43.575	EPSD	ICGC	34.163	Up-regulation
CMGC_DYRK_DYRK1_DYRK1A_ST	P24928	POLR2A	Q13627	DYRK1A	S1917	S1920F	1920	Missense	distal	3	no	40.222	39.665	EPSD	ICGC	34.163	Down-regulation
CMGC_DYRK_DYRK1_DYRK1A_ST	P24928	POLR2A	Q13627	DYRK1A	S1917	P1921H	1921	Missense	distal	4	no	40.222	40.343	EPSD	ICGC	34.163	Up-regulation
CMGC_DYRK_DYRK1_DYRK1A_ST	P24928	POLR2A	Q13627	DYRK1A	S1920	S1927I	1927	Missense	distal	7	no	37.826	40.119	EPSD	ICGC	34.163	Up-regulation
CMGC_DYRK_DYRK1_DYRK1A_ST	P24928	POLR2A	Q13627	DYRK1A	S1920	S1920F	1920	Missense	central	0	yes	37.826	0.000	EPSD	ICGC	34.163	Loss
CMGC_DYRK_DYRK1_DYRK1A_ST	P24928	POLR2A	Q13627	DYRK1A	S1920	P1921H	1921	Missense	proximal	1	no	37.826	-9.417	EPSD	ICGC	34.163	Loss
CMGC_DYRK_DYRK1_DYRK1A_ST	P24928	POLR2A	Q13627	DYRK1A	S1924	S1927I	1927	Missense	distal	3	no	34.769	34.311	EPSD	ICGC	34.163	Down-regulation
CMGC_DYRK_DYRK1_DYRK1A_ST	P24928	POLR2A	Q13627	DYRK1A	S1924	S1920F	1920	Missense	distal	-4	no	34.769	34.745	EPSD	ICGC	34.163	Down-regulation
CMGC_DYRK_DYRK1_DYRK1A_ST	P24928	POLR2A	Q13627	DYRK1A	S1924	P1921H	1921	Missense	distal	-3	no	34.769	30.799	EPSD	ICGC	34.163	Loss
CMGC_DYRK_DYRK1_DYRK1A_ST	P24928	POLR2A	Q13627	DYRK1A	S1927	S1927I	1927	Missense	central	0	yes	41.494	0.000	EPSD	ICGC	34.163	Loss
CMGC_DYRK_DYRK1_DYRK1A_ST	P24928	POLR2A	Q13627	DYRK1A	S1927	S1920F	1920	Missense	distal	-7	no	41.494	42.597	EPSD	ICGC	34.163	Up-regulation
CMGC_DYRK_DYRK1_DYRK1A_ST	P24928	POLR2A	Q13627	DYRK1A	S1927	P1921H	1921	Missense	distal	-6	no	41.494	41.295	EPSD	ICGC	34.163	Down-regulation
CMGC_DYRK_DYRK1_DYRK1A_ST	P24928	POLR2A	Q13627	DYRK1A	S1931	S1927I	1927	Missense	distal	-4	no	36.460	36.416	EPSD	ICGC	34.163	Down-regulation
CMGC_DYRK_DYRK1_DYRK1A_ST	P24928	POLR2A	Q13627	DYRK1A	S1931	S1938P	1938	Missense	distal	7	no	36.460	36.956	EPSD	ICGC	34.163	Up-regulation
CMGC_DYRK_DYRK1_DYRK1A_ST	P24928	POLR2A	Q13627	DYRK1A	S1934	S1927I	1927	Missense	distal	-7	no	42.628	44.116	EPSD	ICGC	34.163	Up-regulation
CMGC_DYRK_DYRK1_DYRK1A_ST	P24928	POLR2A	Q13627	DYRK1A	S1934	S1938P	1938	Missense	distal	4	no	42.628	42.431	EPSD	ICGC	34.163	Down-regulation
CMGC_DYRK_DYRK1_DYRK1A_ST	P24928	POLR2A	Q13627	DYRK1A	T1939	S1938P	1938	Missense	proximal	-1	no	39.329	39.509	EPSD	ICGC	34.163	Up-regulation
CMGC_DYRK_DYRK1_DYRK1A_ST	P24928	POLR2A	Q13627	DYRK1A	S1941	S1938P	1938	Missense	distal	-3	no	36.377	33.605	EPSD	ICGC	34.163	Loss
CMGC_DYRK_DYRK1_DYRK1A_ST	P24928	POLR2A	Q13627	DYRK1A	S1944	S1938P	1938	Missense	distal	-6	no	50.754	50.051	EPSD	ICGC	34.163	Down-regulation
CMGC_DYRK_DYRK1_DYRK1A_ST	P24928	POLR2A	Q13627	DYRK1A	S1948	P1952H	1952	Missense	distal	4	no	34.639	34.759	EPSD	ICGC	34.163	Up-regulation
CMGC_DYRK_DYRK1_DYRK1A_ST	P24928	POLR2A	Q13627	DYRK1A	S1951	P1952H	1952	Missense	proximal	1	no	46.557	-0.686	EPSD	ICGC	34.163	Loss
CMGC_DYRK_DYRK1_DYRK1A_ST	P24928	POLR2A	Q13627	DYRK1A	S1962	P1963L	1963	Missense	proximal	1	no	35.682	-6.648	EPSD	ICGC	34.163	Loss
CMGC_DYRK_DYRK1_DYRK1A_ST	Q13627	DYRK1A	Q13627	DYRK1A	S14	A18V	18	Missense	distal	4	no	40.592	42.568	EPSD	ICGC;COSMIC	34.163	Up-regulation
CMGC_DYRK_DYRK1_DYRK1A_ST	Q13627	DYRK1A	Q13627	DYRK1A	S97	L100F	100	Missense	distal	3	no	68.448	68.405	EPSD	ICGC;COSMIC	34.163	Down-regulation
CMGC_DYRK_DYRK1_DYRK1A_ST	Q13627	DYRK1A	Q13627	DYRK1A	S127	S128I	128	Missense	proximal	1	no	32.198	43.981	EPSD	ICGC	34.163	Gain
CMGC_DYRK_DYRK1_DYRK1A_ST	Q13627	DYRK1A	Q13627	DYRK1A	S496	A498T	498	Missense	proximal	2	no	39.455	38.894	EPSD	ICGC;COSMIC	34.163	Down-regulation
CMGC_DYRK_DYRK1_DYRK1A_ST	Q13627	DYRK1A	Q13627	DYRK1A	S529	R528L	528	Missense	proximal	-1	no	52.145	52.901	PhosphoSitePlus	ICGC;COSMIC	34.163	Up-regulation
CMGC_DYRK_DYRK1_DYRK1A_ST	Q13627	DYRK1A	Q13627	DYRK1A	S758	A761V	761	Missense	distal	3	no	37.400	36.998	EPSD	ICGC;COSMIC	34.163	Down-regulation
CMGC_DYRK_DYRK1_DYRK1A_ST	O95644	NFATC1	Q13627	DYRK1A	S117	S124L	124	Missense	distal	7	no	35.943	38.097	EPSD	ICGC;COSMIC	34.163	Up-regulation
CMGC_DYRK_DYRK1_DYRK1A_ST	O95644	NFATC1	Q13627	DYRK1A	S117	R119H	119	Missense	proximal	2	no	35.943	34.821	EPSD	ICGC;COSMIC	34.163	Down-regulation
CMGC_DYRK_DYRK1_DYRK1A_ST	O95644	NFATC1	Q13627	DYRK1A	S117	E121K	121	Missense	distal	4	no	35.943	35.585	EPSD	ICGC;COSMIC	34.163	Down-regulation
CMGC_DYRK_DYRK1_DYRK1A_ST	O95644	NFATC1	Q13627	DYRK1A	S151	T154M	154	Missense	distal	3	no	38.669	38.835	EPSD	ICGC;COSMIC;CCLE	34.163	Up-regulation
CMGC_DYRK_DYRK1_DYRK1A_ST	O95644	NFATC1	Q13627	DYRK1A	S151	S151P	151	Missense	central	0	yes	38.669	0.000	EPSD	ICGC;COSMIC	34.163	Loss
CMGC_DYRK_DYRK1_DYRK1A_ST	O95644	NFATC1	Q13627	DYRK1A	S151	S158R	158	Missense	distal	7	no	38.669	37.690	EPSD	ICGC;COSMIC	34.163	Down-regulation
CMGC_DYRK_DYRK1_DYRK1A_ST	O95644	NFATC1	Q13627	DYRK1A	S151	S151C	151	Missense	central	0	yes	38.669	0.000	EPSD	ICGC;COSMIC	34.163	Loss
CMGC_DYRK_DYRK1_DYRK1A_ST	O95644	NFATC1	Q13627	DYRK1A	S151	R150L	150	Missense	proximal	-1	no	38.669	39.424	EPSD	ICGC	34.163	Up-regulation
CMGC_DYRK_DYRK1_DYRK1A_ST	O95644	NFATC1	Q13627	DYRK1A	S151	A155S	155	Missense	distal	4	no	38.669	38.209	EPSD	ICGC	34.163	Down-regulation
CMGC_DYRK_DYRK1_DYRK1A_ST	O95644	NFATC1	Q13627	DYRK1A	S151	P152L	152	Missense	proximal	1	no	38.669	-3.662	EPSD	ICGC;COSMIC	34.163	Loss
CMGC_DYRK_DYRK1_DYRK1A_ST	O95644	NFATC1	Q13627	DYRK1A	S151	P146S	146	Missense	distal	-5	no	38.669	37.915	EPSD	ICGC;COSMIC	34.163	Down-regulation
CMGC_DYRK_DYRK1_DYRK1A_ST	O95644	NFATC1	Q13627	DYRK1A	S151	V144I	144	Missense	distal	-7	no	38.669	38.963	EPSD	ICGC;COSMIC	34.163	Up-regulation
CMGC_DYRK_DYRK1_DYRK1A_ST	O95644	NFATC1	Q13627	DYRK1A	S151	T156M	156	Missense	distal	5	no	38.669	31.963	EPSD	ICGC;COSMIC	34.163	Loss
CMGC_DYRK_DYRK1_DYRK1A_ST	O95644	NFATC1	Q13627	DYRK1A	S151	R150W	150	Missense	proximal	-1	no	38.669	39.826	EPSD	ICGC	34.163	Up-regulation
CMGC_DYRK_DYRK1_DYRK1A_ST	O95644	NFATC1	Q13627	DYRK1A	S211	V210M	210	Missense	proximal	-1	no	33.800	34.599	EPSD	ICGC;COSMIC	34.163	Gain
CMGC_DYRK_DYRK1_DYRK1A_ST	O95644	NFATC1	Q13627	DYRK1A	S211	P208S	208	Missense	distal	-3	no	33.800	36.572	EPSD	ICGC	34.163	Gain
CMGC_DYRK_DYRK1_DYRK1A_ST	O95644	NFATC1	Q13627	DYRK1A	S237	A244T	244	Missense	distal	7	no	54.613	53.619	EPSD	ICGC;COSMIC	34.163	Down-regulation
CMGC_DYRK_DYRK1_DYRK1A_ST	O95644	NFATC1	Q13627	DYRK1A	S237	P242S	242	Missense	distal	5	no	54.613	54.675	EPSD	ICGC;COSMIC	34.163	Up-regulation
CMGC_DYRK_DYRK1_DYRK1A_ST	O95644	NFATC1	Q13627	DYRK1A	S237	G232C	232	Missense	distal	-5	no	54.613	53.467	EPSD	ICGC;COSMIC	34.163	Down-regulation
CMGC_DYRK_DYRK1_DYRK1A_ST	O95644	NFATC1	Q13627	DYRK1A	S237	P242L	242	Missense	distal	5	no	54.613	53.728	EPSD	ICGC;COSMIC	34.163	Down-regulation
CMGC_DYRK_DYRK1_DYRK1A_ST	O95644	NFATC1	Q13627	DYRK1A	S237	P234L	234	Missense	distal	-3	no	54.613	52.620	EPSD	ICGC;COSMIC	34.163	Down-regulation
CMGC_DYRK_DYRK1_DYRK1A_ST	O95644	NFATC1	Q13627	DYRK1A	S241	V246L	246	Missense	distal	5	no	31.597	34.304	EPSD	ICGC;COSMIC	34.163	Gain
CMGC_DYRK_DYRK1_DYRK1A_ST	O95644	NFATC1	Q13627	DYRK1A	S245	A244T	244	Missense	proximal	-1	no	35.442	34.740	EPSD	ICGC;COSMIC	34.163	Down-regulation
CMGC_DYRK_DYRK1_DYRK1A_ST	O95644	NFATC1	Q13627	DYRK1A	S245	V246L	246	Missense	proximal	1	no	35.442	2.881	EPSD	ICGC;COSMIC	34.163	Loss
CMGC_DYRK_DYRK1_DYRK1A_ST	O95644	NFATC1	Q13627	DYRK1A	S245	E249D	249	Missense	distal	4	no	35.442	35.700	EPSD	ICGC;COSMIC	34.163	Up-regulation
CMGC_DYRK_DYRK1_DYRK1A_ST	O95644	NFATC1	Q13627	DYRK1A	S245	P242S	242	Missense	distal	-3	no	35.442	38.215	EPSD	ICGC;COSMIC	34.163	Up-regulation
CMGC_DYRK_DYRK1_DYRK1A_ST	O95644	NFATC1	Q13627	DYRK1A	S245	V246I	246	Missense	proximal	1	no	35.442	35.042	EPSD	ICGC;COSMIC	34.163	Down-regulation
CMGC_DYRK_DYRK1_DYRK1A_ST	O95644	NFATC1	Q13627	DYRK1A	S245	P242L	242	Missense	distal	-3	no	35.442	33.449	EPSD	ICGC;COSMIC	34.163	Loss
CMGC_DYRK_DYRK1_DYRK1A_ST	O95644	NFATC1	Q13627	DYRK1A	S261	P262L	262	Missense	proximal	1	no	56.111	13.780	PhosphoSitePlus;EPSD	ICGC;COSMIC	34.163	Loss
CMGC_DYRK_DYRK1_DYRK1A_ST	O95644	NFATC1	Q13627	DYRK1A	S278	R273L	273	Missense	distal	-5	no	55.224	53.312	EPSD;PhosphoSitePlus	ICGC;COSMIC	34.163	Down-regulation
CMGC_DYRK_DYRK1_DYRK1A_ST	O95644	NFATC1	Q13627	DYRK1A	S278	H281D	281	Missense	distal	3	no	55.224	55.171	EPSD;PhosphoSitePlus	ICGC;COSMIC	34.163	Down-regulation
CMGC_DYRK_DYRK1_DYRK1A_ST	O95644	NFATC1	Q13627	DYRK1A	S278	G272V	272	Missense	distal	-6	no	55.224	54.044	EPSD;PhosphoSitePlus	ICGC;COSMIC	34.163	Down-regulation
CMGC_DYRK_DYRK1_DYRK1A_ST	O95644	NFATC1	Q13627	DYRK1A	S278	P275S	275	Missense	distal	-3	no	55.224	57.996	EPSD;PhosphoSitePlus	ICGC	34.163	Up-regulation
CMGC_DYRK_DYRK1_DYRK1A_ST	O95644	NFATC1	Q13627	DYRK1A	S278	P276A	276	Missense	proximal	-2	no	55.224	51.333	EPSD;PhosphoSitePlus	ICGC;COSMIC	34.163	Down-regulation
CMGC_DYRK_DYRK1_DYRK1A_ST	O95644	NFATC1	Q13627	DYRK1A	S278	R273Q	273	Missense	distal	-5	no	55.224	54.072	EPSD;PhosphoSitePlus	ICGC	34.163	Down-regulation
CMGC_DYRK_DYRK1_DYRK1A_ST	O95644	NFATC1	Q13627	DYRK1A	S278	H280Y	280	Missense	proximal	2	no	55.224	55.282	EPSD;PhosphoSitePlus	ICGC;COSMIC	34.163	Up-regulation
CMGC_DYRK_DYRK1_DYRK1A_ST	O95644	NFATC1	Q13627	DYRK1A	S282	H280Y	280	Missense	proximal	-2	no	28.391	34.524	EPSD	ICGC;COSMIC	34.163	Gain
CMGC_DYRK_DYRK1_DYRK1A_ST	O95644	NFATC1	Q13627	DYRK1A	T284	H281D	281	Missense	distal	-3	no	41.433	41.409	EPSD	ICGC;COSMIC	34.163	Down-regulation
CMGC_DYRK_DYRK1_DYRK1A_ST	O95644	NFATC1	Q13627	DYRK1A	T284	S286P	286	Missense	proximal	2	no	41.433	41.533	EPSD	ICGC;COSMIC	34.163	Up-regulation
CMGC_DYRK_DYRK1_DYRK1A_ST	O95644	NFATC1	Q13627	DYRK1A	T284	S290F	290	Missense	distal	6	no	41.433	41.509	EPSD	ICGC;COSMIC	34.163	Up-regulation
CMGC_DYRK_DYRK1_DYRK1A_ST	O95644	NFATC1	Q13627	DYRK1A	T284	H280Y	280	Missense	distal	-4	no	41.433	41.405	EPSD	ICGC;COSMIC	34.163	Down-regulation
CMGC_DYRK_DYRK1_DYRK1A_ST	O95644	NFATC1	Q13627	DYRK1A	T284	P291T	291	Missense	distal	7	no	41.433	42.104	EPSD	ICGC;COSMIC	34.163	Up-regulation
CMGC_DYRK_DYRK1_DYRK1A_ST	O95644	NFATC1	Q13627	DYRK1A	T284	G289S	289	Missense	distal	5	no	41.433	40.206	EPSD	ICGC;COSMIC	34.163	Down-regulation
CMGC_DYRK_DYRK1_DYRK1A_ST	O95644	NFATC1	Q13627	DYRK1A	S286	H281D	281	Missense	distal	-5	no	38.820	38.452	EPSD	ICGC;COSMIC	34.163	Down-regulation
CMGC_DYRK_DYRK1_DYRK1A_ST	O95644	NFATC1	Q13627	DYRK1A	S286	S286P	286	Missense	central	0	yes	38.820	0.000	EPSD	ICGC;COSMIC	34.163	Loss
CMGC_DYRK_DYRK1_DYRK1A_ST	O95644	NFATC1	Q13627	DYRK1A	S286	S290F	290	Missense	distal	4	no	38.820	41.472	EPSD	ICGC;COSMIC	34.163	Up-regulation
CMGC_DYRK_DYRK1_DYRK1A_ST	O95644	NFATC1	Q13627	DYRK1A	S286	H280Y	280	Missense	distal	-6	no	38.820	38.816	EPSD	ICGC;COSMIC	34.163	Down-regulation
CMGC_DYRK_DYRK1_DYRK1A_ST	O95644	NFATC1	Q13627	DYRK1A	S286	P291T	291	Missense	distal	5	no	38.820	40.366	EPSD	ICGC;COSMIC	34.163	Up-regulation
CMGC_DYRK_DYRK1_DYRK1A_ST	O95644	NFATC1	Q13627	DYRK1A	S286	G289S	289	Missense	distal	3	no	38.820	39.081	EPSD	ICGC;COSMIC	34.163	Up-regulation
CMGC_DYRK_DYRK1_DYRK1A_ST	O95644	NFATC1	Q13627	DYRK1A	S373	A367V	367	Missense	distal	-6	no	38.427	36.888	EPSD	ICGC;COSMIC	34.163	Down-regulation
CMGC_DYRK_DYRK1_DYRK1A_ST	O95644	NFATC1	Q13627	DYRK1A	S373	G380D	380	Missense	distal	7	no	38.427	40.126	EPSD	ICGC;COSMIC	34.163	Up-regulation
CMGC_DYRK_DYRK1_DYRK1A_ST	O95644	NFATC1	Q13627	DYRK1A	S403	A397V	397	Missense	distal	-6	no	53.664	52.125	EPSD;PhosphoSitePlus	ICGC;COSMIC	34.163	Down-regulation
CMGC_DYRK_DYRK1_DYRK1A_ST	O95644	NFATC1	Q13627	DYRK1A	S403	P410T	410	Missense	distal	7	no	53.664	54.336	EPSD;PhosphoSitePlus	ICGC;COSMIC	34.163	Up-regulation
CMGC_DYRK_DYRK1_DYRK1A_ST	O95644	NFATC1	Q13627	DYRK1A	S403	P404S	404	Missense	proximal	1	no	53.664	31.711	EPSD;PhosphoSitePlus	ICGC;COSMIC	34.163	Loss
CMGC_DYRK_DYRK1_DYRK1A_ST	O95644	NFATC1	Q13627	DYRK1A	S403	S409R	409	Missense	distal	6	no	53.664	53.603	EPSD;PhosphoSitePlus	ICGC;COSMIC	34.163	Down-regulation
CMGC_DYRK_DYRK1_DYRK1A_ST	O95644	NFATC1	Q13627	DYRK1A	S409	P410T	410	Missense	proximal	1	no	52.496	30.119	EPSD;PhosphoSitePlus	ICGC;COSMIC	34.163	Loss
CMGC_DYRK_DYRK1_DYRK1A_ST	O95644	NFATC1	Q13627	DYRK1A	S409	P404S	404	Missense	distal	-5	no	52.496	51.742	EPSD;PhosphoSitePlus	ICGC;COSMIC	34.163	Down-regulation
CMGC_DYRK_DYRK1_DYRK1A_ST	O95644	NFATC1	Q13627	DYRK1A	S409	P413S	413	Missense	distal	4	no	52.496	52.693	EPSD;PhosphoSitePlus	ICGC;COSMIC	34.163	Up-regulation
CMGC_DYRK_DYRK1_DYRK1A_ST	O95644	NFATC1	Q13627	DYRK1A	S409	S409R	409	Missense	central	0	yes	52.496	0.000	EPSD;PhosphoSitePlus	ICGC;COSMIC	34.163	Loss
CMGC_DYRK_DYRK1_DYRK1A_ST	O95644	NFATC1	Q13627	DYRK1A	S670	R667S	667	Missense	distal	-3	no	38.408	29.818	EPSD	ICGC;COSMIC	34.163	Loss
CMGC_DYRK_DYRK1_DYRK1A_ST	O95644	NFATC1	Q13627	DYRK1A	S670	V674I	674	Missense	distal	4	no	38.408	38.844	EPSD	ICGC;COSMIC	34.163	Up-regulation
CMGC_DYRK_DYRK1_DYRK1A_ST	O95644	NFATC1	Q13627	DYRK1A	S670	V672F	672	Missense	proximal	2	no	38.408	37.891	EPSD	ICGC;COSMIC	34.163	Down-regulation
CMGC_DYRK_DYRK1_DYRK1A_ST	O95644	NFATC1	Q13627	DYRK1A	S670	V674F	674	Missense	distal	4	no	38.408	38.623	EPSD	ICGC;COSMIC	34.163	Up-regulation
CMGC_DYRK_DYRK1_DYRK1A_ST	O95644	NFATC1	Q13627	DYRK1A	S670	S670N	670	Missense	central	0	yes	38.408	0.000	EPSD	ICGC;COSMIC	34.163	Loss
CMGC_DYRK_DYRK1_DYRK1A_ST	O95644	NFATC1	Q13627	DYRK1A	S887	A890D	890	Missense	distal	3	no	43.310	43.010	EPSD	ICGC;COSMIC	34.163	Down-regulation
CMGC_DYRK_DYRK1_DYRK1A_ST	O95644	NFATC1	Q13627	DYRK1A	S887	R893Q	893	Missense	distal	6	no	43.310	43.317	EPSD	ICGC	34.163	Up-regulation
CMGC_DYRK_DYRK1_DYRK1A_ST	O95644	NFATC1	Q13627	DYRK1A	S887	R883C	883	Missense	distal	-4	no	43.310	43.284	EPSD	ICGC	34.163	Down-regulation
CMGC_DYRK_DYRK1_DYRK1A_ST	O95644	NFATC1	Q13627	DYRK1A	S903	P910L	910	Missense	distal	7	no	34.217	35.876	EPSD	ICGC;COSMIC	34.163	Up-regulation
CMGC_DYRK_DYRK1_DYRK1A_ST	O95644	NFATC1	Q13627	DYRK1A	T912	P917A	917	Missense	distal	5	no	37.004	36.687	EPSD	ICGC	34.163	Down-regulation
CMGC_DYRK_DYRK1_DYRK1A_ST	O95644	NFATC1	Q13627	DYRK1A	T912	P910L	910	Missense	proximal	-2	no	37.004	23.276	EPSD	ICGC;COSMIC	34.163	Loss
CMGC_DYRK_DYRK1_DYRK1A_ST	O75533	SF3B1	Q13627	DYRK1A	S194	Q191K	191	Missense	distal	-3	no	29.331	35.238	EPSD	ICGC	34.163	Gain
CMGC_DYRK_DYRK1_DYRK1A_ST	O75533	SF3B1	Q13627	DYRK1A	T207	D201N	201	Missense	distal	-6	no	45.861	45.516	EPSD	ICGC	34.163	Down-regulation
CMGC_DYRK_DYRK1_DYRK1A_ST	O75533	SF3B1	Q13627	DYRK1A	T207	P212L	212	Missense	distal	5	no	45.861	44.976	EPSD	ICGC;COSMIC	34.163	Down-regulation
CMGC_DYRK_DYRK1_DYRK1A_ST	O75533	SF3B1	Q13627	DYRK1A	T211	P212L	212	Missense	proximal	1	no	36.767	-5.564	EPSD	ICGC;COSMIC	34.163	Loss
CMGC_DYRK_DYRK1_DYRK1A_ST	O75533	SF3B1	Q13627	DYRK1A	T244	R238S	238	Missense	distal	-6	no	35.354	35.640	EPSD	ICGC;COSMIC	34.163	Up-regulation
CMGC_DYRK_DYRK1_DYRK1A_ST	O75533	SF3B1	Q13627	DYRK1A	T244	A247E	247	Missense	distal	3	no	35.354	35.236	EPSD	ICGC;COSMIC	34.163	Down-regulation
CMGC_DYRK_DYRK1_DYRK1A_ST	O75533	SF3B1	Q13627	DYRK1A	T261	P262L	262	Missense	proximal	1	no	45.422	3.091	EPSD	ICGC;COSMIC	34.163	Loss
CMGC_DYRK_DYRK1_DYRK1A_ST	O75533	SF3B1	Q13627	DYRK1A	T267	D272H	272	Missense	distal	5	no	47.765	43.908	EPSD	ICGC;COSMIC	34.163	Down-regulation
CMGC_DYRK_DYRK1_DYRK1A_ST	O75533	SF3B1	Q13627	DYRK1A	T267	P262L	262	Missense	distal	-5	no	47.765	46.328	EPSD	ICGC;COSMIC	34.163	Down-regulation
CMGC_DYRK_DYRK1_DYRK1A_ST	O75533	SF3B1	Q13627	DYRK1A	T273	D272H	272	Missense	proximal	-1	no	54.664	53.977	PhosphoSitePlus;EPSD	ICGC;COSMIC	34.163	Down-regulation
CMGC_DYRK_DYRK1_DYRK1A_ST	O75533	SF3B1	Q13627	DYRK1A	T278	D272H	272	Missense	distal	-6	no	35.001	34.866	EPSD	ICGC;COSMIC	34.163	Down-regulation
CMGC_DYRK_DYRK1_DYRK1A_ST	O75533	SF3B1	Q13627	DYRK1A	T278	A284T	284	Missense	distal	6	no	35.001	34.956	EPSD	ICGC;COSMIC	34.163	Down-regulation
CMGC_DYRK_DYRK1_DYRK1A_ST	O75533	SF3B1	Q13627	DYRK1A	T296	R289H	289	Missense	distal	-7	no	39.539	39.738	EPSD	ICGC;COSMIC	34.163	Up-regulation
CMGC_DYRK_DYRK1_DYRK1A_ST	O75533	SF3B1	Q13627	DYRK1A	T313	R315L	315	Missense	proximal	2	no	37.729	36.828	EPSD	ICGC;COSMIC	34.163	Down-regulation
CMGC_DYRK_DYRK1_DYRK1A_ST	O75533	SF3B1	Q13627	DYRK1A	S322	R315L	315	Missense	distal	-7	no	35.765	36.856	EPSD	ICGC;COSMIC	34.163	Up-regulation
CMGC_DYRK_DYRK1_DYRK1A_ST	O75533	SF3B1	Q13627	DYRK1A	S322	P327L	327	Missense	distal	5	no	35.765	34.880	EPSD	ICGC;COSMIC;CCLE	34.163	Down-regulation
CMGC_DYRK_DYRK1_DYRK1A_ST	O75533	SF3B1	Q13627	DYRK1A	T326	A331D	331	Missense	distal	5	no	45.726	45.742	EPSD	ICGC	34.163	Up-regulation
CMGC_DYRK_DYRK1_DYRK1A_ST	O75533	SF3B1	Q13627	DYRK1A	T326	P327L	327	Missense	proximal	1	no	45.726	3.395	EPSD	ICGC;COSMIC;CCLE	34.163	Loss
CMGC_DYRK_DYRK1_DYRK1A_ST	O75533	SF3B1	Q13627	DYRK1A	S344	G347S	347	Missense	distal	3	no	40.717	40.978	EPSD	ICGC;COSMIC	34.163	Up-regulation
CMGC_DYRK_DYRK1_DYRK1A_ST	O75533	SF3B1	Q13627	DYRK1A	S344	P342T	342	Missense	proximal	-2	no	40.717	35.481	EPSD	ICGC;COSMIC	34.163	Down-regulation
CMGC_DYRK_DYRK1_DYRK1A_ST	O75533	SF3B1	Q13627	DYRK1A	S344	P351T	351	Missense	distal	7	no	40.717	41.389	EPSD	ICGC;COSMIC	34.163	Up-regulation
CMGC_DYRK_DYRK1_DYRK1A_ST	O75533	SF3B1	Q13627	DYRK1A	T350	G347S	347	Missense	distal	-3	no	42.910	43.514	EPSD	ICGC;COSMIC	34.163	Up-regulation
CMGC_DYRK_DYRK1_DYRK1A_ST	O75533	SF3B1	Q13627	DYRK1A	T350	T354N	354	Missense	distal	4	no	42.910	43.241	EPSD	ICGC	34.163	Up-regulation
CMGC_DYRK_DYRK1_DYRK1A_ST	O75533	SF3B1	Q13627	DYRK1A	T350	P351T	351	Missense	proximal	1	no	42.910	20.532	EPSD	ICGC;COSMIC	34.163	Loss
CMGC_DYRK_DYRK1_DYRK1A_ST	O75533	SF3B1	Q13627	DYRK1A	T354	G347S	347	Missense	distal	-7	no	42.439	42.501	EPSD	ICGC;COSMIC	34.163	Up-regulation
CMGC_DYRK_DYRK1_DYRK1A_ST	O75533	SF3B1	Q13627	DYRK1A	T354	T354N	354	Missense	central	0	yes	42.439	0.000	EPSD	ICGC	34.163	Loss
CMGC_DYRK_DYRK1_DYRK1A_ST	O75533	SF3B1	Q13627	DYRK1A	T354	P351T	351	Missense	distal	-3	no	42.439	36.191	EPSD	ICGC;COSMIC	34.163	Down-regulation
CMGC_DYRK_DYRK1_DYRK1A_ST	O75533	SF3B1	Q13627	DYRK1A	T358	T354N	354	Missense	distal	-4	no	39.400	39.395	EPSD	ICGC	34.163	Down-regulation
CMGC_DYRK_DYRK1_DYRK1A_ST	O75533	SF3B1	Q13627	DYRK1A	T358	A364D	364	Missense	distal	6	no	39.400	39.447	EPSD	ICGC	34.163	Up-regulation
CMGC_DYRK_DYRK1_DYRK1A_ST	O75533	SF3B1	Q13627	DYRK1A	T358	P351T	351	Missense	distal	-7	no	39.400	39.116	EPSD	ICGC;COSMIC	34.163	Down-regulation
CMGC_DYRK_DYRK1_DYRK1A_ST	O75533	SF3B1	Q13627	DYRK1A	S400	M407V	407	Missense	distal	7	no	54.946	54.632	EPSD	ICGC;COSMIC	34.163	Down-regulation
CMGC_DYRK_DYRK1_DYRK1A_ST	O75533	SF3B1	Q13627	DYRK1A	T434	P427Q	427	Missense	distal	-7	no	53.430	53.843	EPSD;PhosphoSitePlus	ICGC	34.163	Up-regulation
CMGC_DYRK_DYRK1_DYRK1A_ST	O75533	SF3B1	Q13627	DYRK1A	T434	G439C	439	Missense	distal	5	no	53.430	47.479	EPSD;PhosphoSitePlus	ICGC;COSMIC	34.163	Down-regulation
CMGC_DYRK_DYRK1_DYRK1A_ST	O75533	SF3B1	Q13627	DYRK1A	S488	Q492K	492	Missense	distal	4	no	39.998	39.619	EPSD	ICGC	34.163	Down-regulation
CMGC_DYRK_DYRK1_DYRK1A_ST	O75533	SF3B1	Q13627	DYRK1A	S488	E490A	490	Missense	proximal	2	no	39.998	40.101	EPSD	ICGC	34.163	Up-regulation
CMGC_DYRK_DYRK1_DYRK1A_ST	O75533	SF3B1	Q13627	DYRK1A	S541	Q534P	534	Missense	distal	-7	no	36.901	36.488	EPSD	ICGC;COSMIC;CCLE	34.163	Down-regulation
CMGC_DYRK_DYRK1_DYRK1A_ST	O75533	SF3B1	Q13627	DYRK1A	T1021	K1025N	1025	Missense	distal	4	no	39.564	39.844	EPSD	ICGC	34.163	Up-regulation
CMGC_DYRK_DYRK1_DYRK1A_ST	O75533	SF3B1	Q13627	DYRK1A	T1080	T1077K	1077	Missense	distal	-3	no	34.821	44.584	EPSD	ICGC	34.163	Up-regulation
CMGC_DYRK_DYRK1_DYRK1A_ST	O75533	SF3B1	Q13627	DYRK1A	T1170	Y1167H	1167	Missense	distal	-3	no	32.943	35.598	EPSD	ICGC	34.163	Gain
CMGC_DYRK_DYRK1_DYRK1A_ST	O75533	SF3B1	Q13627	DYRK1A	S1271	N1270S	1270	Missense	proximal	-1	no	43.021	42.162	EPSD	ICGC;COSMIC;CCLE	34.163	Down-regulation
CMGC_DYRK_DYRK1_DYRK1A_ST	Q96S94	CCNL2	Q13627	DYRK1A	S25	A19D	19	Missense	distal	-6	no	41.427	40.676	EPSD	ICGC	34.163	Down-regulation
CMGC_DYRK_DYRK1_DYRK1A_ST	Q96S94	CCNL2	Q13627	DYRK1A	S25	G26V	26	Missense	proximal	1	no	41.427	46.257	EPSD	ICGC;COSMIC	34.163	Up-regulation
CMGC_DYRK_DYRK1_DYRK1A_ST	Q96S94	CCNL2	Q13627	DYRK1A	S25	A19T	19	Missense	distal	-6	no	41.427	41.089	EPSD	ICGC;COSMIC	34.163	Down-regulation
CMGC_DYRK_DYRK1_DYRK1A_ST	Q96S94	CCNL2	Q13627	DYRK1A	S32	D39Y	39	Missense	distal	7	no	43.486	44.389	EPSD	ICGC;COSMIC	34.163	Up-regulation
CMGC_DYRK_DYRK1_DYRK1A_ST	Q96S94	CCNL2	Q13627	DYRK1A	S32	G26V	26	Missense	distal	-6	no	43.486	42.307	EPSD	ICGC;COSMIC	34.163	Down-regulation
CMGC_DYRK_DYRK1_DYRK1A_ST	Q96S94	CCNL2	Q13627	DYRK1A	S345	P349L	349	Missense	distal	4	no	41.351	43.398	EPSD	ICGC;COSMIC	34.163	Up-regulation
CMGC_DYRK_DYRK1_DYRK1A_ST	Q96S94	CCNL2	Q13627	DYRK1A	S351	P349L	349	Missense	proximal	-2	no	37.489	23.761	EPSD	ICGC;COSMIC	34.163	Loss
CMGC_DYRK_DYRK1_DYRK1A_ST	Q96S94	CCNL2	Q13627	DYRK1A	T355	P349L	349	Missense	distal	-6	no	36.870	36.928	EPSD	ICGC;COSMIC	34.163	Up-regulation
CMGC_DYRK_DYRK1_DYRK1A_ST	Q96S94	CCNL2	Q13627	DYRK1A	S427	R434H	434	Missense	distal	7	no	57.911	60.934	EPSD	ICGC;COSMIC;CCLE	34.163	Up-regulation
CMGC_DYRK_DYRK1_DYRK1A_ST	Q52LA3	LIN52	Q13627	DYRK1A	S28	W32C	32	Missense	distal	4	no	53.810	52.994	PhosphoSitePlus	ICGC	34.163	Down-regulation
CMGC_DYRK_DYRK1_DYRK1A_ST	Q52LA3	LIN52	Q13627	DYRK1A	S53	S48N	48	Missense	distal	-5	no	46.625	45.253	EPSD	ICGC;COSMIC	34.163	Down-regulation
CMGC_DYRK_DYRK1_DYRK1A_ST	O43597	SPRY2	Q13627	DYRK1A	T75	H79Q	79	Missense	distal	4	no	54.771	55.953	PhosphoSitePlus	ICGC	34.163	Up-regulation
CMGC_DYRK_DYRK1_DYRK1A_ST	P04637	TP53	Q13627	DYRK1A	S15	E11K	11	Missense	distal	-4	no	53.550	53.537	PhosphoSitePlus	ICGC;COSMIC	34.163	Down-regulation
CMGC_DYRK_DYRK1_DYRK1A_ST	P04637	TP53	Q13627	DYRK1A	S33	P34L	34	Missense	proximal	1	no	34.790	-7.541	EPSD	ICGC;COSMIC	34.163	Loss
CMGC_DYRK_DYRK1_DYRK1A_ST	P04637	TP53	Q13627	DYRK1A	S33	S33F	33	Missense	central	0	yes	34.790	0.000	EPSD	ICGC;COSMIC	34.163	Loss
CMGC_DYRK_DYRK1_DYRK1A_ST	P04637	TP53	Q13627	DYRK1A	S33	N30I	30	Missense	distal	-3	no	34.790	50.182	EPSD	ICGC	34.163	Up-regulation
CMGC_DYRK_DYRK1_DYRK1A_ST	P04637	TP53	Q13627	DYRK1A	T81	A88D	88	Missense	distal	7	no	42.596	42.665	EPSD	ICGC	34.163	Up-regulation
CMGC_DYRK_DYRK1_DYRK1A_ST	P04637	TP53	Q13627	DYRK1A	T81	P87Q	87	Missense	distal	6	no	42.596	42.551	EPSD	ICGC;COSMIC	34.163	Down-regulation
CMGC_DYRK_DYRK1_DYRK1A_ST	P04637	TP53	Q13627	DYRK1A	S99	Q100K	100	Missense	proximal	1	no	36.467	35.535	EPSD	ICGC;COSMIC	34.163	Down-regulation
CMGC_DYRK_DYRK1_DYRK1A_ST	P04637	TP53	Q13627	DYRK1A	S99	P92T	92	Missense	distal	-7	no	36.467	36.183	EPSD	ICGC;COSMIC	34.163	Down-regulation
CMGC_DYRK_DYRK1_DYRK1A_ST	P04637	TP53	Q13627	DYRK1A	S99	P92H	92	Missense	distal	-7	no	36.467	36.577	EPSD	ICGC;COSMIC	34.163	Up-regulation
CMGC_DYRK_DYRK1_DYRK1A_ST	P04637	TP53	Q13627	DYRK1A	S99	G105A	105	Missense	distal	6	no	36.467	36.566	EPSD	ICGC;COSMIC	34.163	Up-regulation
CMGC_DYRK_DYRK1_DYRK1A_ST	P04637	TP53	Q13627	DYRK1A	S127	T125R	125	Missense	proximal	-2	no	37.482	41.508	EPSD	ICGC;COSMIC	34.163	Up-regulation
CMGC_DYRK_DYRK1_DYRK1A_ST	P04637	TP53	Q13627	DYRK1A	S127	F134C	134	Missense	distal	7	no	37.482	36.841	EPSD	ICGC;COSMIC;CCLE	34.163	Down-regulation
CMGC_DYRK_DYRK1_DYRK1A_ST	P04637	TP53	Q13627	DYRK1A	S127	C124G	124	Missense	distal	-3	no	37.482	51.793	EPSD	ICGC;COSMIC	34.163	Up-regulation
CMGC_DYRK_DYRK1_DYRK1A_ST	P04637	TP53	Q13627	DYRK1A	S127	C124R	124	Missense	distal	-3	no	37.482	60.987	EPSD	ICGC;COSMIC;GDSC;CCLE	34.163	Up-regulation
CMGC_DYRK_DYRK1_DYRK1A_ST	P04637	TP53	Q13627	DYRK1A	S127	L130H	130	Missense	distal	3	no	37.482	37.559	EPSD	ICGC;COSMIC	34.163	Up-regulation
CMGC_DYRK_DYRK1_DYRK1A_ST	P04637	TP53	Q13627	DYRK1A	S127	T125A	125	Missense	proximal	-2	no	37.482	38.829	EPSD	ICGC;COSMIC	34.163	Up-regulation
CMGC_DYRK_DYRK1_DYRK1A_ST	P04637	TP53	Q13627	DYRK1A	S127	K120N	120	Missense	distal	-7	no	37.482	38.511	EPSD	ICGC;COSMIC;GDSC;CCLE	34.163	Up-regulation
CMGC_DYRK_DYRK1_DYRK1A_ST	P04637	TP53	Q13627	DYRK1A	S127	N131Y	131	Missense	distal	4	no	37.482	38.113	EPSD	ICGC;COSMIC	34.163	Up-regulation
CMGC_DYRK_DYRK1_DYRK1A_ST	P04637	TP53	Q13627	DYRK1A	S127	K120M	120	Missense	distal	-7	no	37.482	38.859	EPSD	ICGC;COSMIC	34.163	Up-regulation
CMGC_DYRK_DYRK1_DYRK1A_ST	P04637	TP53	Q13627	DYRK1A	S127	K132M	132	Missense	distal	5	no	37.482	30.730	EPSD	ICGC;COSMIC;CCLE	34.163	Loss
CMGC_DYRK_DYRK1_DYRK1A_ST	P04637	TP53	Q13627	DYRK1A	S127	M133T	133	Missense	distal	6	no	37.482	37.317	EPSD	ICGC;COSMIC	34.163	Down-regulation
CMGC_DYRK_DYRK1_DYRK1A_ST	P04637	TP53	Q13627	DYRK1A	S127	K120R	120	Missense	distal	-7	no	37.482	37.528	EPSD	ICGC;COSMIC	34.163	Up-regulation
CMGC_DYRK_DYRK1_DYRK1A_ST	P04637	TP53	Q13627	DYRK1A	S127	C124Y	124	Missense	distal	-3	no	37.482	43.000	EPSD	ICGC;COSMIC	34.163	Up-regulation
CMGC_DYRK_DYRK1_DYRK1A_ST	P04637	TP53	Q13627	DYRK1A	T304	H297Q	297	Missense	distal	-7	no	36.536	36.839	EPSD	ICGC	34.163	Up-regulation
CMGC_DYRK_DYRK1_DYRK1A_ST	P04637	TP53	Q13627	DYRK1A	T304	P301T	301	Missense	distal	-3	no	36.536	30.288	EPSD	ICGC;COSMIC	34.163	Loss
CMGC_DYRK_DYRK1_DYRK1A_ST	P04637	TP53	Q13627	DYRK1A	S315	T312I	312	Missense	distal	-3	no	40.613	47.061	EPSD	ICGC;COSMIC	34.163	Up-regulation
CMGC_DYRK_DYRK1_DYRK1A_ST	P04637	TP53	Q13627	DYRK1A	S315	P322T	322	Missense	distal	7	no	40.613	41.285	EPSD	ICGC	34.163	Up-regulation
CMGC_DYRK_DYRK1_DYRK1A_ST	P04637	TP53	Q13627	DYRK1A	S376	T377P	377	Missense	proximal	1	no	24.393	46.771	EPSD	ICGC;COSMIC	34.163	Gain
CMGC_DYRK_DYRK1_DYRK1A_ST	P24385	CCND1	Q13627	DYRK1A	T286	D289N	289	Missense	distal	3	no	45.823	45.904	PhosphoSitePlus	ICGC;COSMIC	34.163	Up-regulation
CMGC_DYRK_DYRK1_DYRK1A_ST	P24385	CCND1	Q13627	DYRK1A	T286	E280D	280	Missense	distal	-6	no	45.823	45.202	PhosphoSitePlus	ICGC	34.163	Down-regulation
CMGC_DYRK_DYRK1_DYRK1A_ST	P24385	CCND1	Q13627	DYRK1A	T286	P287A	287	Missense	proximal	1	no	45.823	15.678	PhosphoSitePlus	ICGC;COSMIC;GDSC;CCLE	34.163	Loss
CMGC_DYRK_DYRK1_DYRK1A_ST	Q12778	FOXO1	Q13627	DYRK1A	S287	S293Y	293	Missense	distal	6	no	36.170	36.286	EPSD	ICGC;COSMIC	34.163	Up-regulation
CMGC_DYRK_DYRK1_DYRK1A_ST	Q12778	FOXO1	Q13627	DYRK1A	S287	A284D	284	Missense	distal	-3	no	36.170	35.231	EPSD	ICGC	34.163	Down-regulation
CMGC_DYRK_DYRK1_DYRK1A_ST	Q12778	FOXO1	Q13627	DYRK1A	S287	Q281K	281	Missense	distal	-6	no	36.170	36.337	EPSD	ICGC;COSMIC	34.163	Up-regulation
CMGC_DYRK_DYRK1_DYRK1A_ST	Q12778	FOXO1	Q13627	DYRK1A	S293	S293Y	293	Missense	central	0	yes	35.996	0.000	EPSD	ICGC;COSMIC	34.163	Loss
CMGC_DYRK_DYRK1_DYRK1A_ST	Q12778	FOXO1	Q13627	DYRK1A	S298	S293Y	293	Missense	distal	-5	no	42.421	42.072	EPSD	ICGC;COSMIC	34.163	Down-regulation
CMGC_DYRK_DYRK1_DYRK1A_ST	Q12778	FOXO1	Q13627	DYRK1A	S325	G326V	326	Missense	proximal	1	no	32.960	37.789	EPSD	ICGC;COSMIC	34.163	Gain
CMGC_DYRK_DYRK1_DYRK1A_ST	Q12778	FOXO1	Q13627	DYRK1A	S329	E334K	334	Missense	distal	5	no	54.730	54.744	PhosphoSitePlus	ICGC;COSMIC;CCLE	34.163	Up-regulation
CMGC_DYRK_DYRK1_DYRK1A_ST	Q12778	FOXO1	Q13627	DYRK1A	S329	G326V	326	Missense	distal	-3	no	54.730	54.653	PhosphoSitePlus	ICGC;COSMIC	34.163	Down-regulation
CMGC_DYRK_DYRK1_DYRK1A_ST	Q12778	FOXO1	Q13627	DYRK1A	T333	E334K	334	Missense	proximal	1	no	29.960	35.371	EPSD	ICGC;COSMIC;CCLE	34.163	Gain
CMGC_DYRK_DYRK1_DYRK1A_ST	Q12778	FOXO1	Q13627	DYRK1A	S470	D475E	475	Missense	distal	5	no	37.884	39.763	EPSD	ICGC	34.163	Up-regulation
CMGC_DYRK_DYRK1_DYRK1A_ST	Q12778	FOXO1	Q13627	DYRK1A	S470	L465F	465	Missense	distal	-5	no	37.884	37.320	EPSD	ICGC;COSMIC	34.163	Down-regulation
CMGC_DYRK_DYRK1_DYRK1A_ST	O76039	CDKL5	Q13627	DYRK1A	S308	L302R	302	Missense	distal	-6	no	54.170	54.530	PhosphoSitePlus	ICGC	34.163	Up-regulation
CMGC_DYRK_DYRK1_DYRK1A_ST	O76039	CDKL5	Q13627	DYRK1A	S308	D304G	304	Missense	distal	-4	no	54.170	54.149	PhosphoSitePlus	ICGC;COSMIC	34.163	Down-regulation
CMGC_DYRK_DYRK1_DYRK1A_ST	O76039	CDKL5	Q13627	DYRK1A	S308	R313I	313	Missense	distal	5	no	54.170	48.570	PhosphoSitePlus	ICGC;COSMIC	34.163	Down-regulation
CMGC_DYRK_DYRK1_DYRK1A_ST	O76039	CDKL5	Q13627	DYRK1A	S392	P390H	390	Missense	proximal	-2	no	37.637	25.005	EPSD	ICGC;COSMIC	34.163	Loss
CMGC_DYRK_DYRK1_DYRK1A_ST	O76039	CDKL5	Q13627	DYRK1A	S479	P474L	474	Missense	distal	-5	no	41.618	40.182	EPSD	ICGC;COSMIC	34.163	Down-regulation
CMGC_DYRK_DYRK1_DYRK1A_ST	O76039	CDKL5	Q13627	DYRK1A	S479	P480L	480	Missense	proximal	1	no	41.618	-0.713	EPSD	ICGC	34.163	Loss
CMGC_DYRK_DYRK1_DYRK1A_ST	O76039	CDKL5	Q13627	DYRK1A	S603	S604P	604	Missense	proximal	1	no	15.543	37.496	EPSD	ICGC;COSMIC	34.163	Gain
CMGC_DYRK_DYRK1_DYRK1A_ST	O76039	CDKL5	Q13627	DYRK1A	S681	H676N	676	Missense	distal	-5	no	38.784	37.532	EPSD	ICGC;COSMIC	34.163	Down-regulation
CMGC_DYRK_DYRK1_DYRK1A_ST	O76039	CDKL5	Q13627	DYRK1A	S714	G713C	713	Missense	proximal	-1	no	36.380	37.248	EPSD	ICGC;COSMIC	34.163	Up-regulation
CMGC_DYRK_DYRK1_DYRK1A_ST	O76039	CDKL5	Q13627	DYRK1A	S720	G713C	713	Missense	distal	-7	no	52.932	53.893	EPSD	ICGC;COSMIC	34.163	Up-regulation
CMGC_DYRK_DYRK1_DYRK1A_ST	O76039	CDKL5	Q13627	DYRK1A	S761	W759L	759	Missense	proximal	-2	no	34.273	34.318	EPSD	ICGC;COSMIC	34.163	Up-regulation
CMGC_DYRK_DYRK1_DYRK1A_ST	O76039	CDKL5	Q13627	DYRK1A	S761	P758Q	758	Missense	distal	-3	no	34.273	31.883	EPSD	ICGC;COSMIC	34.163	Loss
CMGC_DYRK_DYRK1_DYRK1A_ST	O76039	CDKL5	Q13627	DYRK1A	T813	H809Y	809	Missense	distal	-4	no	36.353	36.326	EPSD	ICGC	34.163	Down-regulation
CMGC_DYRK_DYRK1_DYRK1A_ST	P37840	SNCA	Q13627	DYRK1A	T81	E83D	83	Missense	proximal	2	no	38.024	37.301	EPSD	ICGC;COSMIC	34.163	Down-regulation
CMGC_DYRK_DYRK1_DYRK1A_ST	P37840	SNCA	Q13627	DYRK1A	S87	E83D	83	Missense	distal	-4	no	53.617	53.626	PhosphoSitePlus	ICGC;COSMIC	34.163	Up-regulation
CMGC_DYRK_DYRK1_DYRK1A_ST	Q05193	DNM1	Q13627	DYRK1A	S116	G114V	114	Missense	proximal	-2	no	32.587	34.694	EPSD	ICGC	34.163	Gain
CMGC_DYRK_DYRK1_DYRK1A_ST	Q05193	DNM1	Q13627	DYRK1A	S126	H128R	128	Missense	proximal	2	no	38.404	39.525	EPSD	ICGC;COSMIC	34.163	Up-regulation
CMGC_DYRK_DYRK1_DYRK1A_ST	Q05193	DNM1	Q13627	DYRK1A	S126	P127Q	127	Missense	proximal	1	no	38.404	25.740	EPSD	ICGC;COSMIC	34.163	Loss
CMGC_DYRK_DYRK1_DYRK1A_ST	Q05193	DNM1	Q13627	DYRK1A	S774	A770T	770	Missense	distal	-4	no	40.955	40.958	EPSD	ICGC;COSMIC	34.163	Up-regulation
CMGC_DYRK_DYRK1_DYRK1A_ST	Q05193	DNM1	Q13627	DYRK1A	S774	A770D	770	Missense	distal	-4	no	40.955	40.949	EPSD	ICGC	34.163	Down-regulation
CMGC_DYRK_DYRK1_DYRK1A_ST	Q05193	DNM1	Q13627	DYRK1A	S774	G771E	771	Missense	distal	-3	no	40.955	31.812	EPSD	ICGC	34.163	Loss
CMGC_DYRK_DYRK1_DYRK1A_ST	Q05193	DNM1	Q13627	DYRK1A	S778	G771E	771	Missense	distal	-7	no	59.567	59.317	EPSD	ICGC	34.163	Down-regulation
CMGC_DYRK_DYRK1_DYRK1A_ST	Q05193	DNM1	Q13627	DYRK1A	S822	G827S	827	Missense	distal	5	no	39.170	37.943	EPSD	ICGC	34.163	Down-regulation
CMGC_DYRK_DYRK1_DYRK1A_ST	Q05193	DNM1	Q13627	DYRK1A	S822	V815M	815	Missense	distal	-7	no	39.170	39.281	EPSD	ICGC	34.163	Up-regulation
CMGC_DYRK_DYRK1_DYRK1A_ST	Q05193	DNM1	Q13627	DYRK1A	S822	S822P	822	Missense	central	0	yes	39.170	0.000	EPSD	ICGC;COSMIC	34.163	Loss
CMGC_DYRK_DYRK1_DYRK1A_ST	Q05193	DNM1	Q13627	DYRK1A	S851	S847L	847	Missense	distal	-4	no	40.410	40.406	EPSD	ICGC;COSMIC	34.163	Down-regulation
CMGC_DYRK_DYRK1_DYRK1A_ST	Q05193	DNM1	Q13627	DYRK1A	S851	E856Q	856	Missense	distal	5	no	40.410	41.459	EPSD	ICGC;COSMIC	34.163	Up-regulation
CMGC_DYRK_DYRK1_DYRK1A_ST	Q05193	DNM1	Q13627	DYRK1A	S851	G848C	848	Missense	distal	-3	no	40.410	26.100	EPSD	ICGC	34.163	Loss
CMGC_DYRK_DYRK1_DYRK1A_ST	Q05193	DNM1	Q13627	DYRK1A	S851	R854S	854	Missense	distal	3	no	40.410	40.689	EPSD	ICGC;COSMIC	34.163	Up-regulation
CMGC_DYRK_DYRK1_DYRK1A_ST	Q05193	DNM1	Q13627	DYRK1A	S857	E856Q	856	Missense	proximal	-1	no	64.607	64.720	PhosphoSitePlus	ICGC;COSMIC	34.163	Up-regulation
CMGC_DYRK_DYRK1_DYRK1A_ST	Q05193	DNM1	Q13627	DYRK1A	S857	P861H	861	Missense	distal	4	no	64.607	64.727	PhosphoSitePlus	ICGC;COSMIC	34.163	Up-regulation
CMGC_DYRK_DYRK1_DYRK1A_ST	Q05193	DNM1	Q13627	DYRK1A	S857	R854S	854	Missense	distal	-3	no	64.607	56.017	PhosphoSitePlus	ICGC;COSMIC	34.163	Down-regulation
CMGC_DYRK_DYRK1_DYRK1A_ST	Q05193	DNM1	Q13627	DYRK1A	S857	D863N	863	Missense	distal	6	no	64.607	64.526	PhosphoSitePlus	ICGC;COSMIC	34.163	Down-regulation
CMGC_DYRK_HIPK_HIPK1_ST	O60829	PAGE4	Q86Z02	HIPK1	T51	G50E	50	Missense	proximal	-1	no	8.683	8.812	PhosphoSitePlus	ICGC	1.785	Up-regulation
CMGC_DYRK_HIPK_HIPK1_ST	O60829	PAGE4	Q86Z02	HIPK1	S73	D80Y	80	Missense	distal	7	no	1.967	2.011	EPSD	ICGC	1.785	Up-regulation
CMGC_DYRK_HIPK_HIPK1_ST	O60829	PAGE4	Q86Z02	HIPK1	T85	E83Q	83	Missense	proximal	-2	no	3.862	3.551	EPSD	ICGC	1.785	Down-regulation
CMGC_DYRK_HIPK_HIPK1_ST	O60829	PAGE4	Q86Z02	HIPK1	T85	D80Y	80	Missense	distal	-5	no	3.862	3.964	EPSD	ICGC	1.785	Up-regulation
CMGC_DYRK_HIPK_HIPK1_ST	O60829	PAGE4	Q86Z02	HIPK1	T85	P89H	89	Missense	distal	4	no	3.862	3.723	EPSD	ICGC;COSMIC	1.785	Down-regulation
CMGC_DYRK_HIPK_HIPK1_ST	O60829	PAGE4	Q86Z02	HIPK1	T85	P86T	86	Missense	proximal	1	no	3.862	0.466	EPSD	ICGC;COSMIC	1.785	Loss
CMGC_DYRK_HIPK_HIPK1_ST	O60829	PAGE4	Q86Z02	HIPK1	T85	P86Q	86	Missense	proximal	1	no	3.862	0.598	EPSD	ICGC;COSMIC	1.785	Loss
CMGC_DYRK_HIPK_HIPK1_ST	P51608	MECP2	Q86Z02	HIPK1	S80	R85C	85	Missense	distal	5	no	8.533	8.382	EPSD;PhosphoSitePlus	ICGC;COSMIC;CCLE	1.785	Down-regulation
CMGC_DYRK_HIPK_HIPK1_ST	P51608	MECP2	Q86Z02	HIPK1	S80	R85H	85	Missense	distal	5	no	8.533	8.393	EPSD;PhosphoSitePlus	ICGC;COSMIC	1.785	Down-regulation
CMGC_DYRK_HIPK_HIPK1_ST	P51608	MECP2	Q86Z02	HIPK1	S80	A73V	73	Missense	distal	-7	no	8.533	8.515	EPSD;PhosphoSitePlus	ICGC;COSMIC	1.785	Down-regulation
CMGC_DYRK_HIPK_HIPK1_ST	P51608	MECP2	Q86Z02	HIPK1	S80	P75T	75	Missense	distal	-5	no	8.533	8.776	EPSD;PhosphoSitePlus	ICGC	1.785	Up-regulation
CMGC_DYRK_HIPK_HIPK1_ST	P51608	MECP2	Q86Z02	HIPK1	S80	E76K	76	Missense	distal	-4	no	8.533	8.396	EPSD;PhosphoSitePlus	ICGC;COSMIC	1.785	Down-regulation
CMGC_DYRK_HIPK_HIPK1_ST	P51608	MECP2	Q86Z02	HIPK1	S80	S78A	78	Missense	proximal	-2	no	8.533	8.173	EPSD;PhosphoSitePlus	ICGC;COSMIC	1.785	Down-regulation
CMGC_DYRK_HIPK_HIPK1_ST	P51608	MECP2	Q86Z02	HIPK1	S80	R84W	84	Missense	distal	4	no	8.533	8.494	EPSD;PhosphoSitePlus	ICGC;COSMIC	1.785	Down-regulation
CMGC_DYRK_HIPK_HIPK1_ST	P51608	MECP2	Q86Z02	HIPK1	S164	T158K	158	Missense	distal	-6	no	1.708	1.829	EPSD	ICGC	1.785	Gain
CMGC_DYRK_HIPK_HIPK1_ST	P51608	MECP2	Q86Z02	HIPK1	S178	P176S	176	Missense	proximal	-2	no	4.226	4.593	EPSD	ICGC;COSMIC	1.785	Up-regulation
CMGC_DYRK_HIPK_HIPK1_ST	P51608	MECP2	Q86Z02	HIPK1	S216	P217S	217	Missense	proximal	1	no	7.998	4.681	PhosphoSitePlus;EPSD	ICGC;COSMIC	1.785	Down-regulation
CMGC_DYRK_HIPK_HIPK1_ST	P51608	MECP2	Q86Z02	HIPK1	S229	E235K	235	Missense	distal	6	no	3.042	3.131	EPSD	ICGC;COSMIC	1.785	Up-regulation
CMGC_DYRK_HIPK_HIPK1_ST	P51608	MECP2	Q86Z02	HIPK1	S229	G236R	236	Missense	distal	7	no	3.042	3.075	EPSD	ICGC	1.785	Up-regulation
CMGC_DYRK_HIPK_HIPK1_ST	P51608	MECP2	Q86Z02	HIPK1	S229	M224I	224	Missense	distal	-5	no	3.042	2.962	EPSD	ICGC;COSMIC	1.785	Down-regulation
CMGC_DYRK_HIPK_HIPK1_ST	P51608	MECP2	Q86Z02	HIPK1	S350	R354C	354	Missense	distal	4	no	2.272	2.208	EPSD	ICGC;COSMIC;CCLE	1.785	Down-regulation
CMGC_DYRK_HIPK_HIPK1_ST	P51608	MECP2	Q86Z02	HIPK1	S350	S350R	350	Missense	central	0	yes	2.272	0.000	EPSD	ICGC;COSMIC	1.785	Loss
CMGC_DYRK_HIPK_HIPK1_ST	P51608	MECP2	Q86Z02	HIPK1	S350	S356R	356	Missense	distal	6	no	2.272	2.321	EPSD	ICGC	1.785	Up-regulation
CMGC_DYRK_HIPK_HIPK1_ST	P51608	MECP2	Q86Z02	HIPK1	S350	S346N	346	Missense	distal	-4	no	2.272	2.169	EPSD	ICGC	1.785	Down-regulation
CMGC_DYRK_HIPK_HIPK1_ST	P51608	MECP2	Q86Z02	HIPK1	S359	S360L	360	Missense	proximal	1	no	1.812	1.755	EPSD	ICGC;COSMIC	1.785	Loss
CMGC_DYRK_HIPK_HIPK1_ST	P51608	MECP2	Q86Z02	HIPK1	S359	R354C	354	Missense	distal	-5	no	1.812	1.730	EPSD	ICGC;COSMIC;CCLE	1.785	Loss
CMGC_DYRK_HIPK_HIPK1_ST	P51608	MECP2	Q86Z02	HIPK1	S359	P361L	361	Missense	proximal	2	no	1.812	1.272	EPSD	ICGC	1.785	Loss
CMGC_DYRK_HIPK_HIPK1_ST	P51608	MECP2	Q86Z02	HIPK1	S359	S356R	356	Missense	distal	-3	no	1.812	1.811	EPSD	ICGC	1.785	Down-regulation
CMGC_DYRK_HIPK_HIPK1_ST	P51608	MECP2	Q86Z02	HIPK1	S359	P362S	362	Missense	distal	3	no	1.812	1.834	EPSD	ICGC;COSMIC	1.785	Up-regulation
CMGC_DYRK_HIPK_HIPK1_ST	P51608	MECP2	Q86Z02	HIPK1	S359	K363N	363	Missense	distal	4	no	1.812	1.827	EPSD	ICGC	1.785	Up-regulation
CMGC_DYRK_HIPK_HIPK1_ST	P51608	MECP2	Q86Z02	HIPK1	S360	S360L	360	Missense	central	0	yes	3.301	0.000	EPSD	ICGC;COSMIC	1.785	Loss
CMGC_DYRK_HIPK_HIPK1_ST	P51608	MECP2	Q86Z02	HIPK1	S360	R354C	354	Missense	distal	-6	no	3.301	3.272	EPSD	ICGC;COSMIC;CCLE	1.785	Down-regulation
CMGC_DYRK_HIPK_HIPK1_ST	P51608	MECP2	Q86Z02	HIPK1	S360	P361L	361	Missense	proximal	1	no	3.301	-0.072	EPSD	ICGC	1.785	Loss
CMGC_DYRK_HIPK_HIPK1_ST	P51608	MECP2	Q86Z02	HIPK1	S360	S356R	356	Missense	distal	-4	no	3.301	3.175	EPSD	ICGC	1.785	Down-regulation
CMGC_DYRK_HIPK_HIPK1_ST	P51608	MECP2	Q86Z02	HIPK1	S360	P362S	362	Missense	proximal	2	no	3.301	2.819	EPSD	ICGC;COSMIC	1.785	Down-regulation
CMGC_DYRK_HIPK_HIPK1_ST	P51608	MECP2	Q86Z02	HIPK1	S360	K363N	363	Missense	distal	3	no	3.301	3.244	EPSD	ICGC	1.785	Down-regulation
CMGC_DYRK_HIPK_HIPK1_ST	P51608	MECP2	Q86Z02	HIPK1	S401	Q406H	406	Missense	distal	5	no	3.090	3.209	EPSD	ICGC;COSMIC	1.785	Up-regulation
CMGC_DYRK_HIPK_HIPK1_ST	P51608	MECP2	Q86Z02	HIPK1	S411	E415Q	415	Missense	distal	4	no	2.343	2.181	EPSD	ICGC;COSMIC	1.785	Down-regulation
CMGC_DYRK_HIPK_HIPK1_ST	P51608	MECP2	Q86Z02	HIPK1	S411	V412I	412	Missense	proximal	1	no	2.343	2.701	EPSD	ICGC;COSMIC	1.785	Up-regulation
CMGC_DYRK_HIPK_HIPK1_ST	P51608	MECP2	Q86Z02	HIPK1	S411	K417M	417	Missense	distal	6	no	2.343	2.219	EPSD	ICGC;COSMIC	1.785	Down-regulation
CMGC_DYRK_HIPK_HIPK1_ST	P51608	MECP2	Q86Z02	HIPK1	S411	Q406H	406	Missense	distal	-5	no	2.343	2.352	EPSD	ICGC;COSMIC	1.785	Up-regulation
CMGC_DYRK_HIPK_HIPK1_ST	P51608	MECP2	Q86Z02	HIPK1	S411	M418I	418	Missense	distal	7	no	2.343	2.360	EPSD	ICGC;COSMIC	1.785	Up-regulation
CMGC_DYRK_HIPK_HIPK1_ST	P51608	MECP2	Q86Z02	HIPK1	T479	E483K	483	Missense	distal	4	no	3.273	3.190	EPSD	ICGC;COSMIC	1.785	Down-regulation
CMGC_DYRK_HIPK_HIPK1_ST	P51608	MECP2	Q86Z02	HIPK1	T479	R478Q	478	Missense	proximal	-1	no	3.273	3.221	EPSD	ICGC;COSMIC	1.785	Down-regulation
CMGC_DYRK_HIPK_HIPK1_ST	P51608	MECP2	Q86Z02	HIPK1	T479	T479M	479	Missense	central	0	yes	3.273	0.000	EPSD	ICGC;COSMIC	1.785	Loss
Other_NEK_NEK11_NEK11_ST	P30304	CDC25A	Q8NG66	NEK11	S82	S88F	88	Missense	distal	6	no	9.075	9.000	EPSD;PhosphoSitePlus	ICGC;COSMIC	2.788	Down-regulation
Other_NEK_NEK11_NEK11_ST	P30304	CDC25A	Q8NG66	NEK11	S88	S88F	88	Missense	central	0	yes	8.782	0.000	PhosphoSitePlus;EPSD	ICGC;COSMIC	2.788	Loss
Other_NEK_NEK11_NEK11_ST	P30304	CDC25A	Q8NG66	NEK11	S88	D93E	93	Missense	distal	5	no	8.782	8.859	PhosphoSitePlus;EPSD	ICGC	2.788	Up-regulation
Other_NEK_NEK11_NEK11_ST	P30304	CDC25A	Q8NG66	NEK11	S263	S263F	263	Missense	central	0	yes	3.708	0.000	EPSD	ICGC	2.788	Loss
Other_NEK_NEK11_NEK11_ST	P30304	CDC25A	Q8NG66	NEK11	S320	S317Y	317	Missense	distal	-3	no	3.121	3.038	EPSD	ICGC	2.788	Down-regulation
Other_NEK_NEK11_NEK11_ST	P30304	CDC25A	Q8NG66	NEK11	S320	S315Y	315	Missense	distal	-5	no	3.121	3.156	EPSD	ICGC	2.788	Up-regulation
Other_NEK_NEK11_NEK11_ST	P30304	CDC25A	Q8NG66	NEK11	S320	A319E	319	Missense	proximal	-1	no	3.121	3.913	EPSD	ICGC;COSMIC	2.788	Up-regulation
Other_NEK_NEK11_NEK11_ST	P30304	CDC25A	Q8NG66	NEK11	S320	G324R	324	Missense	distal	4	no	3.121	2.550	EPSD	ICGC	2.788	Loss
Other_NEK_NEK11_NEK11_ST	P30304	CDC25A	Q8NG66	NEK11	S342	H348Y	348	Missense	distal	6	no	4.210	4.200	EPSD	ICGC	2.788	Down-regulation
Other_NEK_NEK11_NEK11_ST	P54132	BLM	Q8NG66	NEK11	S17	K24T	24	Missense	distal	7	no	3.432	3.418	EPSD	ICGC	2.788	Down-regulation
Other_NEK_NEK11_NEK11_ST	P54132	BLM	Q8NG66	NEK11	S17	L13I	13	Missense	distal	-4	no	3.432	3.418	EPSD	ICGC;COSMIC	2.788	Down-regulation
Other_NEK_NEK11_NEK11_ST	P54132	BLM	Q8NG66	NEK11	S28	K24T	24	Missense	distal	-4	no	3.082	3.134	EPSD	ICGC	2.788	Up-regulation
Other_NEK_NEK11_NEK11_ST	P54132	BLM	Q8NG66	NEK11	S28	P30R	30	Missense	proximal	2	no	3.082	3.000	EPSD	ICGC;COSMIC	2.788	Down-regulation
Other_NEK_NEK11_NEK11_ST	P54132	BLM	Q8NG66	NEK11	S48	T50S	50	Missense	proximal	2	no	3.483	3.302	EPSD	ICGC;COSMIC	2.788	Down-regulation
Other_NEK_NEK11_NEK11_ST	P54132	BLM	Q8NG66	NEK11	S144	S147Y	147	Missense	distal	3	no	3.260	3.285	EPSD	ICGC	2.788	Up-regulation
Other_NEK_NEK11_NEK11_ST	P54132	BLM	Q8NG66	NEK11	S168	D161Y	161	Missense	distal	-7	no	3.481	3.419	EPSD	ICGC	2.788	Down-regulation
Other_NEK_NEK11_NEK11_ST	P54132	BLM	Q8NG66	NEK11	S338	S336I	336	Missense	proximal	-2	no	8.770	8.751	PhosphoSitePlus	ICGC	2.788	Down-regulation
Other_NEK_NEK11_NEK11_ST	P54132	BLM	Q8NG66	NEK11	S338	V334F	334	Missense	distal	-4	no	8.770	8.741	PhosphoSitePlus	ICGC	2.788	Down-regulation
Other_NEK_NEK11_NEK11_ST	P54132	BLM	Q8NG66	NEK11	S338	V334I	334	Missense	distal	-4	no	8.770	8.402	PhosphoSitePlus	ICGC;COSMIC	2.788	Down-regulation
Other_NEK_NEK11_NEK11_ST	P54132	BLM	Q8NG66	NEK11	S349	M348I	348	Missense	proximal	-1	no	3.252	3.020	EPSD	ICGC;COSMIC;GDSC	2.788	Down-regulation
Other_NEK_NEK11_NEK11_ST	P54132	BLM	Q8NG66	NEK11	S349	E346K	346	Missense	distal	-3	no	3.252	3.186	EPSD	ICGC;COSMIC	2.788	Down-regulation
Other_NEK_NEK11_NEK11_ST	P54132	BLM	Q8NG66	NEK11	S358	Q365L	365	Missense	distal	7	no	3.870	3.949	EPSD	ICGC;COSMIC	2.788	Up-regulation
Other_NEK_NEK11_NEK11_ST	P54132	BLM	Q8NG66	NEK11	S434	P438S	438	Missense	distal	4	no	2.917	2.189	EPSD	ICGC;COSMIC	2.788	Loss
Other_NEK_NEK11_NEK11_ST	P54132	BLM	Q8NG66	NEK11	S443	S449C	449	Missense	distal	6	no	4.037	3.975	EPSD	ICGC;COSMIC	2.788	Down-regulation
Other_NEK_NEK11_NEK11_ST	P54132	BLM	Q8NG66	NEK11	S443	M450I	450	Missense	distal	7	no	4.037	4.000	EPSD	ICGC;COSMIC	2.788	Down-regulation
Other_NEK_NEK11_NEK11_ST	P54132	BLM	Q8NG66	NEK11	S443	P438S	438	Missense	distal	-5	no	4.037	3.998	EPSD	ICGC;COSMIC	2.788	Down-regulation
Other_NEK_NEK11_NEK11_ST	P54132	BLM	Q8NG66	NEK11	T528	T526P	526	Missense	proximal	-2	no	3.192	3.170	EPSD	ICGC;COSMIC	2.788	Down-regulation
Other_NEK_NEK11_NEK11_ST	P54132	BLM	Q8NG66	NEK11	T528	V530E	530	Missense	proximal	2	no	3.192	3.475	EPSD	ICGC	2.788	Up-regulation
Other_NEK_NEK11_NEK11_ST	P54132	BLM	Q8NG66	NEK11	S580	S579Y	579	Missense	proximal	-1	no	3.086	2.902	EPSD	ICGC;COSMIC	2.788	Down-regulation
Other_NEK_NEK11_NEK11_ST	P54132	BLM	Q8NG66	NEK11	S580	S580F	580	Missense	central	0	yes	3.086	0.000	EPSD	ICGC;COSMIC	2.788	Loss
Other_NEK_NEK11_NEK11_ST	P54132	BLM	Q8NG66	NEK11	S601	S601Y	601	Missense	central	0	yes	2.848	0.000	EPSD	ICGC;COSMIC	2.788	Loss
Other_NEK_NEK11_NEK11_ST	P54132	BLM	Q8NG66	NEK11	S646	R643H	643	Missense	distal	-3	no	3.176	3.174	EPSD	ICGC;COSMIC;GDSC	2.788	Down-regulation
Other_NEK_NEK11_NEK11_ST	P54132	BLM	Q8NG66	NEK11	S646	Q645K	645	Missense	proximal	-1	no	3.176	3.135	EPSD	ICGC;COSMIC	2.788	Down-regulation
Other_NEK_NEK11_NEK11_ST	P54132	BLM	Q8NG66	NEK11	S646	R643L	643	Missense	distal	-3	no	3.176	3.172	EPSD	ICGC;COSMIC	2.788	Down-regulation
Other_NEK_NEK11_NEK11_ST	P54132	BLM	Q8NG66	NEK11	S646	S648N	648	Missense	proximal	2	no	3.176	3.368	EPSD	ICGC	2.788	Up-regulation
Other_NEK_NEK11_NEK11_ST	P54132	BLM	Q8NG66	NEK11	S1135	R1139L	1139	Missense	distal	4	no	1.847	3.084	EPSD	ICGC;COSMIC	2.788	Gain
Other_NEK_NEK11_NEK11_ST	P54132	BLM	Q8NG66	NEK11	S1138	R1144S	1144	Missense	distal	6	no	3.400	3.464	EPSD	ICGC;COSMIC	2.788	Up-regulation
Other_NEK_NEK11_NEK11_ST	P54132	BLM	Q8NG66	NEK11	S1138	A1142T	1142	Missense	distal	4	no	3.400	2.932	EPSD	ICGC	2.788	Down-regulation
Other_NEK_NEK11_NEK11_ST	P54132	BLM	Q8NG66	NEK11	S1138	R1139L	1139	Missense	proximal	1	no	3.400	3.412	EPSD	ICGC;COSMIC	2.788	Up-regulation
Other_NEK_NEK11_NEK11_ST	P54132	BLM	Q8NG66	NEK11	S1138	G1132E	1132	Missense	distal	-6	no	3.400	3.615	EPSD	ICGC	2.788	Up-regulation
Other_NEK_NEK11_NEK11_ST	P54132	BLM	Q8NG66	NEK11	S1280	I1279V	1279	Missense	proximal	-1	no	2.855	2.760	EPSD	ICGC;COSMIC	2.788	Loss
Other_NEK_NEK11_NEK11_ST	P54132	BLM	Q8NG66	NEK11	S1290	P1297Q	1297	Missense	distal	7	no	2.965	2.923	EPSD	ICGC;COSMIC	2.788	Down-regulation
Other_NEK_NEK11_NEK11_ST	P54132	BLM	Q8NG66	NEK11	S1295	P1297Q	1297	Missense	proximal	2	no	3.026	2.990	EPSD	ICGC;COSMIC	2.788	Down-regulation
TK_Jak_JAK2_Y	P62993	GRB2	O60674	JAK2	Y7	D14E	14	Missense	distal	7	no	6.767	6.785	EPSD;PhosphoSitePlus	ICGC	5.995	Up-regulation
TK_Jak_JAK2_Y	P62993	GRB2	O60674	JAK2	Y52	P57T	57	Missense	distal	5	no	9.250	9.014	EPSD;PhosphoSitePlus	ICGC	5.995	Down-regulation
TK_Jak_JAK2_Y	Q13153	PAK1	O60674	JAK2	Y142	T136K	136	Missense	distal	-6	no	5.826	6.221	EPSD	ICGC	5.995	Gain
TK_Jak_JAK2_Y	Q13153	PAK1	O60674	JAK2	Y285	V284M	284	Missense	proximal	-1	no	9.010	10.282	PhosphoSitePlus;EPSD	ICGC;COSMIC	5.995	Up-regulation
TK_Jak_JAK2_Y	O14744	PRMT5	O60674	JAK2	Y297	P294T	294	Missense	distal	-3	no	9.120	7.339	EPSD;PhosphoSitePlus	ICGC	5.995	Down-regulation
TK_Jak_JAK2_Y	Q9UGK3	STAP2	O60674	JAK2	Y250	E248G	248	Missense	proximal	-2	no	11.373	9.129	PhosphoSitePlus;EPSD	ICGC;COSMIC	5.995	Down-regulation
TK_Jak_JAK2_Y	Q9UGK3	STAP2	O60674	JAK2	Y250	Y256F	256	Missense	distal	6	no	11.373	11.416	PhosphoSitePlus;EPSD	ICGC	5.995	Up-regulation
TK_Jak_JAK2_Y	Q9UGK3	STAP2	O60674	JAK2	Y250	K252N	252	Missense	proximal	2	no	11.373	8.928	PhosphoSitePlus;EPSD	ICGC;COSMIC	5.995	Down-regulation
TK_Jak_JAK2_Y	Q9UGK3	STAP2	O60674	JAK2	Y250	L245M	245	Missense	distal	-5	no	11.373	11.312	PhosphoSitePlus;EPSD	ICGC	5.995	Down-regulation
TK_Jak_JAK2_Y	Q9UGK3	STAP2	O60674	JAK2	Y310	N309T	309	Missense	proximal	-1	no	9.636	9.282	EPSD;PhosphoSitePlus	ICGC;COSMIC	5.995	Down-regulation
TK_Jak_JAK2_Y	O60674	JAK2	O60674	JAK2	Y119	R115I	115	Missense	distal	-4	no	13.126	12.744	EPSD;PhosphoSitePlus	ICGC;COSMIC	5.995	Down-regulation
TK_Jak_JAK2_Y	O60674	JAK2	O60674	JAK2	Y201	S203Y	203	Missense	proximal	2	no	6.956	4.973	EPSD	ICGC;COSMIC	5.995	Loss
TK_Jak_JAK2_Y	O60674	JAK2	O60674	JAK2	Y221	T225I	225	Missense	distal	4	no	11.172	11.303	EPSD	ICGC	5.995	Up-regulation
TK_Jak_JAK2_Y	O60674	JAK2	O60674	JAK2	Y382	D378Y	378	Missense	distal	-4	no	6.018	5.913	EPSD	ICGC	5.995	Loss
TK_Jak_JAK2_Y	O60674	JAK2	O60674	JAK2	Y570	G571S	571	Missense	proximal	1	no	9.653	9.484	EPSD;PhosphoSitePlus	ICGC;COSMIC	5.995	Down-regulation
TK_Jak_JAK2_Y	O60674	JAK2	O60674	JAK2	Y868	D873N	873	Missense	distal	5	no	8.754	8.565	EPSD	ICGC;COSMIC	5.995	Down-regulation
TK_Jak_JAK2_Y	O60674	JAK2	O60674	JAK2	Y868	V863M	863	Missense	distal	-5	no	8.754	8.731	EPSD	ICGC;COSMIC	5.995	Down-regulation
TK_Jak_JAK2_Y	O60674	JAK2	O60674	JAK2	Y1007	P1013A	1013	Missense	distal	6	no	9.986	10.077	EPSD	ICGC;COSMIC	5.995	Up-regulation
TK_Jak_JAK2_Y	O60674	JAK2	O60674	JAK2	Y1008	P1013A	1013	Missense	distal	5	no	8.850	6.324	EPSD	ICGC;COSMIC	5.995	Down-regulation
TK_Jak_JAK2_Y	Q15910	EZH2	O60674	JAK2	Y641	Y641F	641	Missense	central	0	yes	9.471	0.000	PhosphoSitePlus	ICGC;COSMIC	5.995	Loss
TK_Jak_JAK2_Y	Q15910	EZH2	O60674	JAK2	Y641	Y641H	641	Missense	central	0	yes	9.471	0.000	PhosphoSitePlus	ICGC;COSMIC	5.995	Loss
TK_Jak_JAK2_Y	Q15910	EZH2	O60674	JAK2	Y641	I638M	638	Missense	distal	-3	no	9.471	9.552	PhosphoSitePlus	ICGC;COSMIC	5.995	Up-regulation
TK_Jak_JAK2_Y	Q15910	EZH2	O60674	JAK2	Y641	Y641N	641	Missense	central	0	yes	9.471	0.000	PhosphoSitePlus	ICGC;COSMIC	5.995	Loss
TK_Jak_JAK2_Y	Q15910	EZH2	O60674	JAK2	Y641	Y641S	641	Missense	central	0	yes	9.471	0.000	PhosphoSitePlus	ICGC;COSMIC	5.995	Loss
TK_Jak_JAK2_Y	Q15910	EZH2	O60674	JAK2	Y641	Y641C	641	Missense	central	0	yes	9.471	0.000	PhosphoSitePlus	ICGC;COSMIC;CCLE	5.995	Loss
TK_Jak_JAK2_Y	Q15910	EZH2	O60674	JAK2	Y641	F637I	637	Missense	distal	-4	no	9.471	9.555	PhosphoSitePlus	ICGC	5.995	Up-regulation
TK_Jak_JAK2_Y	Q15910	EZH2	O60674	JAK2	Y641	F637L	637	Missense	distal	-4	no	9.471	9.546	PhosphoSitePlus	ICGC	5.995	Up-regulation
TK_Jak_JAK2_Y	Q15910	EZH2	O60674	JAK2	Y641	C642R	642	Missense	proximal	1	no	9.471	9.864	PhosphoSitePlus	ICGC;COSMIC	5.995	Up-regulation
TK_Jak_JAK2_Y	P41597	CCR2	O60674	JAK2	Y139	V143F	143	Missense	distal	4	no	9.206	8.617	PhosphoSitePlus	ICGC	5.995	Down-regulation
TK_Jak_JAK2_Y	P28482	MAPK1	O60674	JAK2	Y187	T181K	181	Missense	distal	-6	no	12.522	12.917	PhosphoSitePlus	ICGC	5.995	Up-regulation
TK_Jak_JAK2_Y	P28482	MAPK1	O60674	JAK2	Y187	T185K	185	Missense	proximal	-2	no	12.522	12.726	PhosphoSitePlus	ICGC	5.995	Up-regulation
TK_Jak_JAK2_Y	P28482	MAPK1	O60674	JAK2	Y187	W192L	192	Missense	distal	5	no	12.522	11.282	PhosphoSitePlus	ICGC;COSMIC	5.995	Down-regulation
TK_Jak_JAK2_Y	O14543	SOCS3	O60674	JAK2	Y204	D202E	202	Missense	proximal	-2	no	6.124	4.659	EPSD;PhosphoSitePlus	ICGC;COSMIC	5.995	Loss
TK_Jak_JAK2_Y	P40763	STAT3	O60674	JAK2	Y705	A702T	702	Missense	distal	-3	no	10.032	7.480	PhosphoSitePlus	ICGC;COSMIC	5.995	Down-regulation
TK_Jak_JAK2_Y	Q15118	PDK1	O60674	JAK2	Y49	F52L	52	Missense	distal	3	no	7.161	9.185	EPSD	ICGC;COSMIC	5.995	Up-regulation
TK_Jak_JAK2_Y	Q15118	PDK1	O60674	JAK2	Y49	G44C	44	Missense	distal	-5	no	7.161	7.250	EPSD	ICGC;COSMIC	5.995	Up-regulation
TK_Jak_JAK2_Y	Q15118	PDK1	O60674	JAK2	Y243	C240F	240	Missense	distal	-3	no	9.334	8.677	PhosphoSitePlus	ICGC;COSMIC	5.995	Down-regulation
TK_Jak_JAK2_Y	Q15118	PDK1	O60674	JAK2	Y243	R238C	238	Missense	distal	-5	no	9.334	9.435	PhosphoSitePlus	ICGC	5.995	Up-regulation
TK_Jak_JAK2_Y	Q15118	PDK1	O60674	JAK2	Y243	P248H	248	Missense	distal	5	no	9.334	10.099	PhosphoSitePlus	ICGC;COSMIC	5.995	Up-regulation
TK_Jak_JAK2_Y	Q15118	PDK1	O60674	JAK2	Y403	W408L	408	Missense	distal	5	no	6.722	5.482	EPSD	ICGC;COSMIC	5.995	Loss
TK_Jak_JAK2_Y	P27361	MAPK3	O60674	JAK2	Y204	T198I	198	Missense	distal	-6	no	13.438	13.022	PhosphoSitePlus	ICGC;COSMIC	5.995	Down-regulation
TK_Jak_JAK2_Y	Q9UQC2	GAB2	O60674	JAK2	Y48	Y49H	49	Missense	proximal	1	no	6.170	6.334	EPSD	ICGC;COSMIC	5.995	Up-regulation
TK_Jak_JAK2_Y	Q99683	MAP3K5	O60674	JAK2	Y718	P721H	721	Missense	distal	3	no	10.831	9.269	PhosphoSitePlus	ICGC	5.995	Down-regulation
TK_Jak_JAK2_Y	Q99683	MAP3K5	O60674	JAK2	Y718	S716R	716	Missense	proximal	-2	no	10.831	10.642	PhosphoSitePlus	ICGC	5.995	Down-regulation
TK_Jak_JAK2_Y	Q99683	MAP3K5	O60674	JAK2	Y718	S719Y	719	Missense	proximal	1	no	10.831	10.780	PhosphoSitePlus	ICGC;COSMIC	5.995	Down-regulation
TK_Jak_JAK2_Y	P42224	STAT1	O60674	JAK2	Y68	L73F	73	Missense	distal	5	no	5.598	6.437	EPSD	ICGC;COSMIC	5.995	Gain
TK_Jak_JAK2_Y	P42224	STAT1	O60674	JAK2	Y170	D168G	168	Missense	proximal	-2	no	6.275	2.566	EPSD	ICGC;COSMIC	5.995	Loss
TK_Jak_JAK2_Y	P42224	STAT1	O60674	JAK2	Y170	E169K	169	Missense	proximal	-1	no	6.275	5.112	EPSD	ICGC;COSMIC	5.995	Loss
TK_Jak_JAK2_Y	P42224	STAT1	O60674	JAK2	Y170	D168N	168	Missense	proximal	-2	no	6.275	4.324	EPSD	ICGC	5.995	Loss
TK_Jak_JAK2_Y	P42224	STAT1	O60674	JAK2	Y170	E164K	164	Missense	distal	-6	no	6.275	6.130	EPSD	ICGC	5.995	Down-regulation
TK_Jak_JAK2_Y	P42224	STAT1	O60674	JAK2	Y701	T704N	704	Missense	distal	3	no	8.804	6.651	PhosphoSitePlus	ICGC;COSMIC	5.995	Down-regulation
TK_Jak_JAK2_Y	P42224	STAT1	O60674	JAK2	Y701	K703E	703	Missense	proximal	2	no	8.804	6.193	PhosphoSitePlus	ICGC	5.995	Down-regulation
TK_Jak_JAK2_Y	Q92888	ARHGEF1	O60674	JAK2	Y738	W731G	731	Missense	distal	-7	no	9.080	8.977	PhosphoSitePlus	ICGC;COSMIC	5.995	Down-regulation
CMGC_CDK_CDK4_CDK4_ST	Q8IZL8	PELP1	P11802	CDK4	T49	S42Y	42	Missense	distal	-7	no	2.657	2.061	EPSD	ICGC	2.642	Loss
CMGC_CDK_CDK4_CDK4_ST	Q8IZL8	PELP1	P11802	CDK4	T647	P648T	648	Missense	proximal	1	no	9.108	2.581	EPSD	ICGC	2.642	Loss
CMGC_CDK_CDK4_CDK4_ST	Q8IZL8	PELP1	P11802	CDK4	S991	P993L	993	Missense	proximal	2	no	9.416	9.347	EPSD	ICGC	2.642	Down-regulation
CMGC_CDK_CDK4_CDK4_ST	P06400	RB1	P11802	CDK4	T5	A10S	10	Missense	distal	5	no	7.270	7.255	EPSD	ICGC	2.642	Down-regulation
CMGC_CDK_CDK4_CDK4_ST	P06400	RB1	P11802	CDK4	T5	A11T	11	Missense	distal	6	no	7.270	7.225	EPSD	ICGC;COSMIC	2.642	Down-regulation
CMGC_CDK_CDK4_CDK4_ST	P06400	RB1	P11802	CDK4	S230	D224E	224	Missense	distal	-6	no	7.809	7.685	EPSD	ICGC;COSMIC	2.642	Down-regulation
CMGC_CDK_CDK4_CDK4_ST	P06400	RB1	P11802	CDK4	S249	R251L	251	Missense	proximal	2	no	8.504	8.398	EPSD	ICGC	2.642	Down-regulation
CMGC_CDK_CDK4_CDK4_ST	P06400	RB1	P11802	CDK4	S249	G256C	256	Missense	distal	7	no	8.504	8.513	EPSD	ICGC	2.642	Up-regulation
CMGC_CDK_CDK4_CDK4_ST	P06400	RB1	P11802	CDK4	T252	R251L	251	Missense	proximal	-1	no	8.096	8.237	EPSD;PhosphoSitePlus	ICGC	2.642	Up-regulation
CMGC_CDK_CDK4_CDK4_ST	P06400	RB1	P11802	CDK4	T252	G256C	256	Missense	distal	4	no	8.096	7.923	EPSD;PhosphoSitePlus	ICGC	2.642	Down-regulation
CMGC_CDK_CDK4_CDK4_ST	P06400	RB1	P11802	CDK4	T356	Q354H	354	Missense	proximal	-2	no	7.068	7.092	EPSD;PhosphoSitePlus	ICGC;COSMIC	2.642	Up-regulation
CMGC_CDK_CDK4_CDK4_ST	P06400	RB1	P11802	CDK4	S567	L572I	572	Missense	distal	5	no	8.961	8.965	EPSD	ICGC;COSMIC	2.642	Up-regulation
CMGC_CDK_CDK4_CDK4_ST	P06400	RB1	P11802	CDK4	S567	D571Y	571	Missense	distal	4	no	8.961	8.877	EPSD	ICGC	2.642	Down-regulation
CMGC_CDK_CDK4_CDK4_ST	P06400	RB1	P11802	CDK4	S567	A562P	562	Missense	distal	-5	no	8.961	8.860	EPSD	ICGC;COSMIC;GDSC;CCLE	2.642	Down-regulation
CMGC_CDK_CDK4_CDK4_ST	P06400	RB1	P11802	CDK4	S567	L564F	564	Missense	distal	-3	no	8.961	8.925	EPSD	ICGC	2.642	Down-regulation
CMGC_CDK_CDK4_CDK4_ST	P06400	RB1	P11802	CDK4	S780	P783L	783	Missense	distal	3	no	8.334	7.435	PhosphoSitePlus;EPSD	ICGC	2.642	Down-regulation
CMGC_CDK_CDK4_CDK4_ST	P06400	RB1	P11802	CDK4	S788	P783L	783	Missense	distal	-5	no	9.839	9.824	EPSD;PhosphoSitePlus	ICGC	2.642	Down-regulation
CMGC_CDK_CDK4_CDK4_ST	P06400	RB1	P11802	CDK4	S795	L797S	797	Missense	proximal	2	no	8.275	8.502	EPSD;PhosphoSitePlus	ICGC;COSMIC	2.642	Up-regulation
CMGC_CDK_CDK4_CDK4_ST	P06400	RB1	P11802	CDK4	S795	G801E	801	Missense	distal	6	no	8.275	8.441	EPSD;PhosphoSitePlus	ICGC	2.642	Up-regulation
CMGC_CDK_CDK4_CDK4_ST	P06400	RB1	P11802	CDK4	S807	G801E	801	Missense	distal	-6	no	8.321	7.983	EPSD;PhosphoSitePlus	ICGC	2.642	Down-regulation
CMGC_CDK_CDK4_CDK4_ST	Q08999	RBL2	P11802	CDK4	S8	P10L	10	Missense	proximal	2	no	7.843	7.775	EPSD	ICGC;COSMIC	2.642	Down-regulation
CMGC_CDK_CDK4_CDK4_ST	Q08999	RBL2	P11802	CDK4	S8	P14L	14	Missense	distal	6	no	7.843	7.821	EPSD	ICGC	2.642	Down-regulation
CMGC_CDK_CDK4_CDK4_ST	Q08999	RBL2	P11802	CDK4	S40	E39K	39	Missense	proximal	-1	no	8.516	8.425	EPSD	ICGC;COSMIC	2.642	Down-regulation
CMGC_CDK_CDK4_CDK4_ST	Q08999	RBL2	P11802	CDK4	S40	A38S	38	Missense	proximal	-2	no	8.516	8.610	EPSD	ICGC	2.642	Up-regulation
CMGC_CDK_CDK4_CDK4_ST	Q08999	RBL2	P11802	CDK4	S40	Q46K	46	Missense	distal	6	no	8.516	8.584	EPSD	ICGC;COSMIC	2.642	Up-regulation
CMGC_CDK_CDK4_CDK4_ST	Q08999	RBL2	P11802	CDK4	S40	P36L	36	Missense	distal	-4	no	8.516	8.517	EPSD	ICGC;COSMIC	2.642	Up-regulation
CMGC_CDK_CDK4_CDK4_ST	Q08999	RBL2	P11802	CDK4	T42	E39K	39	Missense	distal	-3	no	6.730	6.700	EPSD	ICGC;COSMIC	2.642	Down-regulation
CMGC_CDK_CDK4_CDK4_ST	Q08999	RBL2	P11802	CDK4	T42	A38S	38	Missense	distal	-4	no	6.730	6.729	EPSD	ICGC	2.642	Down-regulation
CMGC_CDK_CDK4_CDK4_ST	Q08999	RBL2	P11802	CDK4	T42	Q46K	46	Missense	distal	4	no	6.730	6.608	EPSD	ICGC;COSMIC	2.642	Down-regulation
CMGC_CDK_CDK4_CDK4_ST	Q08999	RBL2	P11802	CDK4	T42	P36L	36	Missense	distal	-6	no	6.730	6.882	EPSD	ICGC;COSMIC	2.642	Up-regulation
CMGC_CDK_CDK4_CDK4_ST	Q08999	RBL2	P11802	CDK4	S662	Y667C	667	Missense	distal	5	no	7.975	7.983	EPSD	ICGC;COSMIC	2.642	Up-regulation
CMGC_CDK_CDK4_CDK4_ST	Q08999	RBL2	P11802	CDK4	S662	R669S	669	Missense	distal	7	no	7.975	7.990	EPSD	ICGC	2.642	Up-regulation
CMGC_CDK_CDK4_CDK4_ST	Q08999	RBL2	P11802	CDK4	S671	Y667C	667	Missense	distal	-4	no	2.809	2.810	EPSD	ICGC;COSMIC	2.642	Up-regulation
CMGC_CDK_CDK4_CDK4_ST	Q08999	RBL2	P11802	CDK4	S671	S672F	672	Missense	proximal	1	no	2.809	3.332	EPSD	ICGC	2.642	Up-regulation
CMGC_CDK_CDK4_CDK4_ST	Q08999	RBL2	P11802	CDK4	S671	R669S	669	Missense	proximal	-2	no	2.809	2.925	EPSD	ICGC	2.642	Up-regulation
CMGC_CDK_CDK4_CDK4_ST	Q08999	RBL2	P11802	CDK4	S671	P674T	674	Missense	distal	3	no	2.809	2.016	EPSD	ICGC;COSMIC	2.642	Loss
CMGC_CDK_CDK4_CDK4_ST	Q08999	RBL2	P11802	CDK4	S672	Y667C	667	Missense	distal	-5	no	7.567	7.530	EPSD;PhosphoSitePlus	ICGC;COSMIC	2.642	Down-regulation
CMGC_CDK_CDK4_CDK4_ST	Q08999	RBL2	P11802	CDK4	S672	S672F	672	Missense	central	0	yes	7.567	0.000	EPSD;PhosphoSitePlus	ICGC	2.642	Loss
CMGC_CDK_CDK4_CDK4_ST	Q08999	RBL2	P11802	CDK4	S672	R669S	669	Missense	distal	-3	no	7.567	7.462	EPSD;PhosphoSitePlus	ICGC	2.642	Down-regulation
CMGC_CDK_CDK4_CDK4_ST	Q08999	RBL2	P11802	CDK4	S672	P674T	674	Missense	proximal	2	no	7.567	7.537	EPSD;PhosphoSitePlus	ICGC;COSMIC	2.642	Down-regulation
CMGC_CDK_CDK4_CDK4_ST	Q08999	RBL2	P11802	CDK4	S688	D691V	691	Missense	distal	3	no	7.073	7.135	EPSD	ICGC;COSMIC	2.642	Up-regulation
CMGC_CDK_CDK4_CDK4_ST	Q08999	RBL2	P11802	CDK4	S688	G693E	693	Missense	distal	5	no	7.073	7.052	EPSD	ICGC;COSMIC	2.642	Down-regulation
CMGC_CDK_CDK4_CDK4_ST	Q08999	RBL2	P11802	CDK4	T694	D691V	691	Missense	distal	-3	no	6.552	6.551	EPSD	ICGC;COSMIC	2.642	Down-regulation
CMGC_CDK_CDK4_CDK4_ST	Q08999	RBL2	P11802	CDK4	T694	P699T	699	Missense	distal	5	no	6.552	6.587	EPSD	ICGC;COSMIC	2.642	Up-regulation
CMGC_CDK_CDK4_CDK4_ST	Q08999	RBL2	P11802	CDK4	T694	R697C	697	Missense	distal	3	no	6.552	6.111	EPSD	ICGC;COSMIC	2.642	Down-regulation
CMGC_CDK_CDK4_CDK4_ST	Q08999	RBL2	P11802	CDK4	T694	G693E	693	Missense	proximal	-1	no	6.552	6.225	EPSD	ICGC;COSMIC	2.642	Down-regulation
CMGC_CDK_CDK4_CDK4_ST	Q08999	RBL2	P11802	CDK4	S952	S952C	952	Missense	central	0	yes	8.031	0.000	EPSD	ICGC;COSMIC	2.642	Loss
CMGC_CDK_CDK4_CDK4_ST	Q08999	RBL2	P11802	CDK4	S952	D945E	945	Missense	distal	-7	no	8.031	8.261	EPSD	ICGC	2.642	Up-regulation
CMGC_CDK_CDK4_CDK4_ST	Q08999	RBL2	P11802	CDK4	S1035	A1031G	1031	Missense	distal	-4	no	8.592	8.593	EPSD;PhosphoSitePlus	ICGC;COSMIC	2.642	Up-regulation
CMGC_CDK_CDK4_CDK4_ST	Q08050	FOXM1	P11802	CDK4	S4	R6C	6	Missense	proximal	2	no	8.427	8.253	EPSD;PhosphoSitePlus	ICGC;COSMIC	2.642	Down-regulation
CMGC_CDK_CDK4_CDK4_ST	Q08050	FOXM1	P11802	CDK4	S35	S41C	41	Missense	distal	6	no	8.292	8.075	EPSD;PhosphoSitePlus	ICGC;COSMIC	2.642	Down-regulation
CMGC_CDK_CDK4_CDK4_ST	Q08050	FOXM1	P11802	CDK4	S331	P335T	335	Missense	distal	4	no	8.282	8.303	EPSD	ICGC	2.642	Up-regulation
CMGC_CDK_CDK4_CDK4_ST	Q08050	FOXM1	P11802	CDK4	S331	P335S	335	Missense	distal	4	no	8.282	8.076	EPSD	ICGC	2.642	Down-regulation
CMGC_CDK_CDK4_CDK4_ST	Q08050	FOXM1	P11802	CDK4	S508	P509T	509	Missense	proximal	1	no	9.538	3.012	EPSD;PhosphoSitePlus	ICGC;COSMIC	2.642	Down-regulation
CMGC_CDK_CDK4_CDK4_ST	Q08050	FOXM1	P11802	CDK4	T510	P509T	509	Missense	proximal	-1	no	8.407	8.368	PhosphoSitePlus;EPSD	ICGC;COSMIC	2.642	Down-regulation
CMGC_CDK_CDK4_CDK4_ST	Q08050	FOXM1	P11802	CDK4	T627	G634R	634	Missense	distal	7	no	7.652	7.672	EPSD;PhosphoSitePlus	ICGC	2.642	Up-regulation
CMGC_CDK_CDK4_CDK4_ST	Q08050	FOXM1	P11802	CDK4	S638	G634R	634	Missense	distal	-4	no	7.518	7.517	EPSD	ICGC	2.642	Down-regulation
CMGC_CDK_CDK4_CDK4_ST	P30304	CDC25A	P11802	CDK4	S18	P25T	25	Missense	distal	7	no	8.502	8.495	EPSD	ICGC;COSMIC	2.642	Down-regulation
CMGC_CDK_CDK4_CDK4_ST	P30304	CDC25A	P11802	CDK4	S88	S88F	88	Missense	central	0	yes	7.444	0.000	EPSD	ICGC;COSMIC	2.642	Loss
CMGC_CDK_CDK4_CDK4_ST	P30304	CDC25A	P11802	CDK4	S88	D93E	93	Missense	distal	5	no	7.444	7.433	EPSD	ICGC	2.642	Down-regulation
CMGC_CDK_CDK4_CDK4_ST	P30304	CDC25A	P11802	CDK4	S116	P117Q	117	Missense	proximal	1	no	8.452	1.283	EPSD	ICGC	2.642	Loss
CMGC_CDK_CDK4_CDK4_ST	P30304	CDC25A	P11802	CDK4	S261	R255Q	255	Missense	distal	-6	no	8.023	8.029	EPSD	ICGC;COSMIC;GDSC	2.642	Up-regulation
CMGC_CDK_CDK4_CDK4_ST	P30304	CDC25A	P11802	CDK4	S261	N254K	254	Missense	distal	-7	no	8.023	8.063	EPSD	ICGC	2.642	Up-regulation
CMGC_CDK_CDK4_CDK4_ST	P30304	CDC25A	P11802	CDK4	S261	S263F	263	Missense	proximal	2	no	8.023	7.723	EPSD	ICGC	2.642	Down-regulation
CMGC_CDK_CDK4_CDK4_ST	P30304	CDC25A	P11802	CDK4	S283	P285H	285	Missense	proximal	2	no	7.257	7.167	EPSD	ICGC;COSMIC	2.642	Down-regulation
CMGC_CDK_CDK4_CDK4_ST	P30304	CDC25A	P11802	CDK4	S298	T303A	303	Missense	distal	5	no	7.647	7.640	EPSD	ICGC;COSMIC	2.642	Down-regulation
CMGC_CDK_CDK4_CDK4_ST	P30304	CDC25A	P11802	CDK4	S321	S317Y	317	Missense	distal	-4	no	6.140	6.141	EPSD	ICGC	2.642	Up-regulation
CMGC_CDK_CDK4_CDK4_ST	P30304	CDC25A	P11802	CDK4	S321	S315Y	315	Missense	distal	-6	no	6.140	6.435	EPSD	ICGC	2.642	Up-regulation
CMGC_CDK_CDK4_CDK4_ST	P30304	CDC25A	P11802	CDK4	S321	A319E	319	Missense	proximal	-2	no	6.140	6.081	EPSD	ICGC;COSMIC	2.642	Down-regulation
CMGC_CDK_CDK4_CDK4_ST	P30304	CDC25A	P11802	CDK4	S321	G324R	324	Missense	distal	3	no	6.140	6.701	EPSD	ICGC	2.642	Up-regulation
CMGC_CDK_CDK4_CDK4_ST	Q12778	FOXO1	P11802	CDK4	T231	M238T	238	Missense	distal	7	no	2.670	2.677	EPSD	ICGC;COSMIC	2.642	Up-regulation
CMGC_CDK_CDK4_CDK4_ST	Q12778	FOXO1	P11802	CDK4	T231	S234N	234	Missense	distal	3	no	2.670	2.223	EPSD	ICGC;COSMIC	2.642	Loss
CMGC_CDK_CDK4_CDK4_ST	Q12778	FOXO1	P11802	CDK4	S279	A284D	284	Missense	distal	5	no	3.246	3.269	EPSD	ICGC	2.642	Up-regulation
CMGC_CDK_CDK4_CDK4_ST	Q12778	FOXO1	P11802	CDK4	S279	Q281K	281	Missense	proximal	2	no	3.246	3.371	EPSD	ICGC;COSMIC	2.642	Up-regulation
CMGC_CDK_CDK4_CDK4_ST	Q12778	FOXO1	P11802	CDK4	S287	S293Y	293	Missense	distal	6	no	6.464	6.295	EPSD	ICGC;COSMIC	2.642	Down-regulation
CMGC_CDK_CDK4_CDK4_ST	Q12778	FOXO1	P11802	CDK4	S287	A284D	284	Missense	distal	-3	no	6.464	6.577	EPSD	ICGC	2.642	Up-regulation
CMGC_CDK_CDK4_CDK4_ST	Q12778	FOXO1	P11802	CDK4	S287	Q281K	281	Missense	distal	-6	no	6.464	6.420	EPSD	ICGC;COSMIC	2.642	Down-regulation
CMGC_CDK_CDK4_CDK4_ST	Q12778	FOXO1	P11802	CDK4	S298	S293Y	293	Missense	distal	-5	no	7.696	7.575	EPSD	ICGC;COSMIC	2.642	Down-regulation
CMGC_CDK_CDK4_CDK4_ST	Q12778	FOXO1	P11802	CDK4	S303	N309S	309	Missense	distal	6	no	2.543	2.682	EPSD	ICGC;COSMIC	2.642	Gain
CMGC_CDK_CDK4_CDK4_ST	Q12778	FOXO1	P11802	CDK4	T312	N309S	309	Missense	distal	-3	no	2.680	2.579	EPSD	ICGC;COSMIC	2.642	Loss
CMGC_CDK_CDK4_CDK4_ST	Q12778	FOXO1	P11802	CDK4	S329	E334K	334	Missense	distal	5	no	8.621	8.614	EPSD	ICGC;COSMIC;CCLE	2.642	Down-regulation
CMGC_CDK_CDK4_CDK4_ST	Q12778	FOXO1	P11802	CDK4	S329	G326V	326	Missense	distal	-3	no	8.621	8.574	EPSD	ICGC;COSMIC	2.642	Down-regulation
CMGC_CDK_CDK4_CDK4_ST	Q12778	FOXO1	P11802	CDK4	S383	P384T	384	Missense	proximal	1	no	7.429	0.903	EPSD	ICGC	2.642	Loss
CMGC_CDK_CDK4_CDK4_ST	Q12778	FOXO1	P11802	CDK4	S394	Q392K	392	Missense	proximal	-2	no	5.987	6.063	EPSD	ICGC	2.642	Up-regulation
CMGC_CDK_CDK4_CDK4_ST	Q12778	FOXO1	P11802	CDK4	T402	P403S	403	Missense	proximal	1	no	6.520	0.333	EPSD	ICGC	2.642	Loss
CMGC_CDK_CDK4_CDK4_ST	Q12778	FOXO1	P11802	CDK4	T402	P409T	409	Missense	distal	7	no	6.520	6.513	EPSD	ICGC	2.642	Down-regulation
CMGC_CDK_CDK4_CDK4_ST	Q12778	FOXO1	P11802	CDK4	T402	P409Q	409	Missense	distal	7	no	6.520	6.509	EPSD	ICGC	2.642	Down-regulation
CMGC_CDK_CDK4_CDK4_ST	Q12778	FOXO1	P11802	CDK4	S416	P410Q	410	Missense	distal	-6	no	7.267	7.333	EPSD	ICGC	2.642	Up-regulation
CMGC_CDK_CDK4_CDK4_ST	Q12778	FOXO1	P11802	CDK4	S416	P409T	409	Missense	distal	-7	no	7.267	7.057	EPSD	ICGC	2.642	Down-regulation
CMGC_CDK_CDK4_CDK4_ST	Q12778	FOXO1	P11802	CDK4	S416	P409Q	409	Missense	distal	-7	no	7.267	6.921	EPSD	ICGC	2.642	Down-regulation
CMGC_CDK_CDK4_CDK4_ST	Q12778	FOXO1	P11802	CDK4	S468	D475E	475	Missense	distal	7	no	3.023	3.033	EPSD	ICGC	2.642	Up-regulation
CMGC_CDK_CDK4_CDK4_ST	Q12778	FOXO1	P11802	CDK4	S468	L465F	465	Missense	distal	-3	no	3.023	2.988	EPSD	ICGC;COSMIC	2.642	Down-regulation
CMGC_CDK_CDK4_CDK4_ST	Q12778	FOXO1	P11802	CDK4	S470	D475E	475	Missense	distal	5	no	8.382	8.371	EPSD	ICGC	2.642	Down-regulation
CMGC_CDK_CDK4_CDK4_ST	Q12778	FOXO1	P11802	CDK4	S470	L465F	465	Missense	distal	-5	no	8.382	8.368	EPSD	ICGC;COSMIC	2.642	Down-regulation
CMGC_CDK_CDK4_CDK4_ST	Q12778	FOXO1	P11802	CDK4	T478	D475E	475	Missense	distal	-3	no	6.760	6.696	EPSD	ICGC	2.642	Down-regulation
CMGC_CDK_CDK4_CDK4_ST	Q12778	FOXO1	P11802	CDK4	T478	G483V	483	Missense	distal	5	no	6.760	6.754	EPSD	ICGC;COSMIC	2.642	Down-regulation
CMGC_CDK_CDK4_CDK4_ST	P84022	SMAD3	P11802	CDK4	S204	D201N	201	Missense	distal	-3	no	7.126	7.050	EPSD;PhosphoSitePlus	ICGC	2.642	Down-regulation
CMGC_CDK_CDK4_CDK4_ST	P84022	SMAD3	P11802	CDK4	S208	D201N	201	Missense	distal	-7	no	7.256	7.402	PhosphoSitePlus;EPSD	ICGC	2.642	Up-regulation
CMGC_CDK_CDK4_CDK4_ST	P84022	SMAD3	P11802	CDK4	S213	L219F	219	Missense	distal	6	no	7.568	7.523	EPSD;PhosphoSitePlus	ICGC;COSMIC	2.642	Down-regulation
CMGC_CDK_CDK4_CDK4_ST	P84022	SMAD3	P11802	CDK4	S416	S423T	423	Missense	distal	7	no	8.706	8.690	EPSD	ICGC;COSMIC	2.642	Down-regulation
CMGC_CDK_CDK4_CDK4_ST	P84022	SMAD3	P11802	CDK4	S416	S422F	422	Missense	distal	6	no	8.706	8.481	EPSD	ICGC;COSMIC	2.642	Down-regulation
CMGC_CDK_CDK4_CDK4_ST	P84022	SMAD3	P11802	CDK4	S416	G415V	415	Missense	proximal	-1	no	8.706	8.503	EPSD	ICGC	2.642	Down-regulation
CMGC_CDK_CDK4_CDK4_ST	P84022	SMAD3	P11802	CDK4	S416	S423N	423	Missense	distal	7	no	8.706	8.691	EPSD	ICGC;COSMIC	2.642	Down-regulation
CMGC_CDK_CDK4_CDK4_ST	P84022	SMAD3	P11802	CDK4	S416	L411F	411	Missense	distal	-5	no	8.706	8.692	EPSD	ICGC;COSMIC	2.642	Down-regulation
CMGC_CDK_CDK4_CDK4_ST	P84022	SMAD3	P11802	CDK4	S416	R420S	420	Missense	distal	4	no	8.706	8.475	EPSD	ICGC;COSMIC	2.642	Down-regulation
CMGC_CDK_CDK4_CDK4_ST	P84022	SMAD3	P11802	CDK4	S416	L411I	411	Missense	distal	-5	no	8.706	8.721	EPSD	ICGC;COSMIC	2.642	Up-regulation
CMGC_CDK_CDK4_CDK4_ST	P26358	DNMT1	P11802	CDK4	S127	V120L	120	Missense	distal	-7	no	7.446	7.468	PhosphoSitePlus;EPSD	ICGC	2.642	Up-regulation
CMGC_CDK_CDK4_CDK4_ST	P26358	DNMT1	P11802	CDK4	T137	P138L	138	Missense	proximal	1	no	7.575	-0.005	EPSD	ICGC;COSMIC	2.642	Loss
CMGC_CDK_CDK4_CDK4_ST	P26358	DNMT1	P11802	CDK4	T137	P135T	135	Missense	proximal	-2	no	7.575	7.153	EPSD	ICGC	2.642	Down-regulation
CMGC_CDK_CDK4_CDK4_ST	P26358	DNMT1	P11802	CDK4	T137	R139K	139	Missense	proximal	2	no	7.575	7.591	EPSD	ICGC;COSMIC	2.642	Up-regulation
CMGC_CDK_CDK4_CDK4_ST	P26358	DNMT1	P11802	CDK4	T137	R139S	139	Missense	proximal	2	no	7.575	7.696	EPSD	ICGC;COSMIC	2.642	Up-regulation
CMGC_CDK_CDK4_CDK4_ST	P26358	DNMT1	P11802	CDK4	T137	R136H	136	Missense	proximal	-1	no	7.575	7.724	EPSD	ICGC;COSMIC	2.642	Up-regulation
CMGC_CDK_CDK4_CDK4_ST	P26358	DNMT1	P11802	CDK4	S152	A147T	147	Missense	distal	-5	no	8.760	8.711	EPSD	ICGC	2.642	Down-regulation
CMGC_CDK_CDK4_CDK4_ST	P26358	DNMT1	P11802	CDK4	S154	A147T	147	Missense	distal	-7	no	7.264	7.070	EPSD	ICGC	2.642	Down-regulation
CMGC_CDK_CDK4_CDK4_ST	Q14814	MEF2D	P11802	CDK4	S98	P101T	101	Missense	distal	3	no	8.576	7.782	PhosphoSitePlus;EPSD	ICGC	2.642	Down-regulation
CMGC_CDK_CDK4_CDK4_ST	Q14814	MEF2D	P11802	CDK4	S98	P101L	101	Missense	distal	3	no	8.576	7.677	PhosphoSitePlus;EPSD	ICGC;GDSC;CCLE	2.642	Down-regulation
CMGC_CDK_CDK4_CDK4_ST	Q14814	MEF2D	P11802	CDK4	S110	S110G	110	Missense	central	0	yes	7.937	0.000	EPSD;PhosphoSitePlus	ICGC	2.642	Loss
CMGC_CDK_CDK4_CDK4_ST	Q14814	MEF2D	P11802	CDK4	S219	S212R	212	Missense	distal	-7	no	6.601	6.113	EPSD	ICGC	2.642	Down-regulation
CMGC_CDK_CDK4_CDK4_ST	P38398	BRCA1	P11802	CDK4	S114	D120G	120	Missense	distal	6	no	6.552	6.450	EPSD	ICGC;COSMIC	2.642	Down-regulation
CMGC_CDK_CDK4_CDK4_ST	P38398	BRCA1	P11802	CDK4	S114	H117N	117	Missense	distal	3	no	6.552	6.713	EPSD	ICGC;COSMIC	2.642	Up-regulation
CMGC_CDK_CDK4_CDK4_ST	P38398	BRCA1	P11802	CDK4	T208	G211K	211	Missense	distal	3	no	5.791	6.361	EPSD	ICGC	2.642	Up-regulation
CMGC_CDK_CDK4_CDK4_ST	P38398	BRCA1	P11802	CDK4	T208	R213S	213	Missense	distal	5	no	5.791	5.768	EPSD	ICGC;COSMIC	2.642	Down-regulation
CMGC_CDK_CDK4_CDK4_ST	P38398	BRCA1	P11802	CDK4	T208	P209H	209	Missense	proximal	1	no	5.791	-0.792	EPSD	ICGC;COSMIC	2.642	Loss
CMGC_CDK_CDK4_CDK4_ST	P38398	BRCA1	P11802	CDK4	S510	R507T	507	Missense	distal	-3	no	3.301	3.296	EPSD	ICGC;COSMIC	2.642	Down-regulation
CMGC_CDK_CDK4_CDK4_ST	P38398	BRCA1	P11802	CDK4	S632	N635K	635	Missense	distal	3	no	7.444	7.659	PhosphoSitePlus	ICGC	2.642	Up-regulation
CMGC_CDK_CDK4_CDK4_ST	P38398	BRCA1	P11802	CDK4	S645	Q640P	640	Missense	distal	-5	no	2.758	2.734	EPSD	ICGC;COSMIC	2.642	Down-regulation
CMGC_CDK_CDK4_CDK4_ST	P38398	BRCA1	P11802	CDK4	S868	S868C	868	Missense	central	0	yes	2.727	0.000	EPSD	ICGC;COSMIC	2.642	Loss
CMGC_CDK_CDK4_CDK4_ST	P38398	BRCA1	P11802	CDK4	T1163	S1164F	1164	Missense	proximal	1	no	2.150	2.672	EPSD	ICGC;COSMIC	2.642	Gain
CMGC_CDK_CDK4_CDK4_ST	P38398	BRCA1	P11802	CDK4	S1191	H1197N	1197	Missense	distal	6	no	8.595	8.641	EPSD	ICGC;COSMIC	2.642	Up-regulation
CMGC_CDK_CDK4_CDK4_ST	Q96KS0	EGLN2	P11802	CDK4	S74	R77L	77	Missense	distal	3	no	7.682	7.330	EPSD	ICGC;COSMIC	2.642	Down-regulation
CMGC_CDK_CDK4_CDK4_ST	Q96KS0	EGLN2	P11802	CDK4	S130	D127G	127	Missense	distal	-3	no	6.672	6.718	PhosphoSitePlus	ICGC;COSMIC	2.642	Up-regulation
CMGC_CDK_CDK4_CDK4_ST	Q96KS0	EGLN2	P11802	CDK4	S130	P129S	129	Missense	proximal	-1	no	6.672	6.424	PhosphoSitePlus	ICGC	2.642	Down-regulation
CMGC_CDK_CDK4_CDK4_ST	P15923	TCF3	P11802	CDK4	S55	P54S	54	Missense	proximal	-1	no	2.813	2.566	EPSD	ICGC	2.642	Loss
CMGC_CDK_CDK4_CDK4_ST	P15923	TCF3	P11802	CDK4	S134	P140S	140	Missense	distal	6	no	9.027	9.184	EPSD	ICGC;CCLE	2.642	Up-regulation
CMGC_CDK_CDK4_CDK4_ST	P15923	TCF3	P11802	CDK4	S134	G136W	136	Missense	proximal	2	no	9.027	9.165	EPSD	ICGC;COSMIC	2.642	Up-regulation
CMGC_CDK_CDK4_CDK4_ST	P15923	TCF3	P11802	CDK4	S139	P140S	140	Missense	proximal	1	no	8.524	2.336	EPSD;PhosphoSitePlus	ICGC;CCLE	2.642	Loss
CMGC_CDK_CDK4_CDK4_ST	P15923	TCF3	P11802	CDK4	S139	G136W	136	Missense	distal	-3	no	8.524	8.474	EPSD;PhosphoSitePlus	ICGC;COSMIC	2.642	Down-regulation
CMGC_CDK_CDK4_CDK4_ST	P15923	TCF3	P11802	CDK4	S139	K144Q	144	Missense	distal	5	no	8.524	8.535	EPSD;PhosphoSitePlus	ICGC;COSMIC	2.642	Up-regulation
CMGC_CDK_CDK4_CDK4_ST	P15923	TCF3	P11802	CDK4	S141	P140S	140	Missense	proximal	-1	no	4.069	3.821	EPSD	ICGC;CCLE	2.642	Down-regulation
CMGC_CDK_CDK4_CDK4_ST	P15923	TCF3	P11802	CDK4	S141	G136W	136	Missense	distal	-5	no	4.069	4.145	EPSD	ICGC;COSMIC	2.642	Up-regulation
CMGC_CDK_CDK4_CDK4_ST	P15923	TCF3	P11802	CDK4	S141	K144Q	144	Missense	distal	3	no	4.069	3.712	EPSD	ICGC;COSMIC	2.642	Down-regulation
CMGC_CDK_CDK4_CDK4_ST	P15923	TCF3	P11802	CDK4	T146	P140S	140	Missense	distal	-6	no	2.853	2.643	EPSD	ICGC;CCLE	2.642	Down-regulation
CMGC_CDK_CDK4_CDK4_ST	P15923	TCF3	P11802	CDK4	T146	K144Q	144	Missense	proximal	-2	no	2.853	2.776	EPSD	ICGC;COSMIC	2.642	Down-regulation
CMGC_CDK_CDK4_CDK4_ST	P15923	TCF3	P11802	CDK4	S154	R159Q	159	Missense	distal	5	no	5.149	5.157	EPSD	ICGC;COSMIC	2.642	Up-regulation
CMGC_CDK_CDK4_CDK4_ST	P15923	TCF3	P11802	CDK4	T205	A212V	212	Missense	distal	7	no	7.694	7.679	EPSD	ICGC;COSMIC	2.642	Down-regulation
CMGC_CDK_CDK4_CDK4_ST	P15923	TCF3	P11802	CDK4	S208	A212V	212	Missense	distal	4	no	2.490	2.787	EPSD	ICGC;COSMIC	2.642	Gain
CMGC_CDK_CDK4_CDK4_ST	P15923	TCF3	P11802	CDK4	S229	P231Q	231	Missense	proximal	2	no	8.112	8.041	EPSD	ICGC;COSMIC	2.642	Down-regulation
CMGC_CDK_CDK4_CDK4_ST	P15923	TCF3	P11802	CDK4	S229	P231L	231	Missense	proximal	2	no	8.112	8.043	EPSD	ICGC;COSMIC	2.642	Down-regulation
CMGC_CDK_CDK4_CDK4_ST	P15923	TCF3	P11802	CDK4	S229	P231S	231	Missense	proximal	2	no	8.112	8.271	EPSD	ICGC	2.642	Up-regulation
CMGC_CDK_CDK4_CDK4_ST	P15923	TCF3	P11802	CDK4	S229	A234V	234	Missense	distal	5	no	8.112	8.139	EPSD	ICGC	2.642	Up-regulation
CMGC_CDK_CDK4_CDK4_ST	P15923	TCF3	P11802	CDK4	S244	P250L	250	Missense	distal	6	no	3.540	3.518	EPSD	ICGC;COSMIC	2.642	Down-regulation
CMGC_CDK_CDK4_CDK4_ST	P15923	TCF3	P11802	CDK4	S244	S245F	245	Missense	proximal	1	no	3.540	4.062	EPSD	ICGC	2.642	Up-regulation
CMGC_CDK_CDK4_CDK4_ST	P15923	TCF3	P11802	CDK4	S244	L249P	249	Missense	distal	5	no	3.540	3.489	EPSD	ICGC;COSMIC	2.642	Down-regulation
CMGC_CDK_CDK4_CDK4_ST	P15923	TCF3	P11802	CDK4	S245	P250L	250	Missense	distal	5	no	9.863	9.914	PhosphoSitePlus;EPSD	ICGC;COSMIC	2.642	Up-regulation
CMGC_CDK_CDK4_CDK4_ST	P15923	TCF3	P11802	CDK4	S245	S245F	245	Missense	central	0	yes	9.863	0.000	PhosphoSitePlus;EPSD	ICGC	2.642	Loss
CMGC_CDK_CDK4_CDK4_ST	P15923	TCF3	P11802	CDK4	S245	L249P	249	Missense	distal	4	no	9.863	9.703	PhosphoSitePlus;EPSD	ICGC;COSMIC	2.642	Down-regulation
CMGC_CDK_CDK4_CDK4_ST	P15923	TCF3	P11802	CDK4	S253	P250L	250	Missense	distal	-3	no	4.675	4.932	EPSD	ICGC;COSMIC	2.642	Up-regulation
CMGC_CDK_CDK4_CDK4_ST	P15923	TCF3	P11802	CDK4	S253	L249P	249	Missense	distal	-4	no	4.675	4.673	EPSD	ICGC;COSMIC	2.642	Down-regulation
CMGC_CDK_CDK4_CDK4_ST	P15923	TCF3	P11802	CDK4	S306	G303S	303	Missense	distal	-3	no	2.964	2.741	EPSD	ICGC;COSMIC;CCLE	2.642	Down-regulation
CMGC_CDK_CDK4_CDK4_ST	P15923	TCF3	P11802	CDK4	T308	G302C	302	Missense	distal	-6	no	7.602	7.431	EPSD	ICGC;COSMIC	2.642	Down-regulation
CMGC_CDK_CDK4_CDK4_ST	P15923	TCF3	P11802	CDK4	T308	A314V	314	Missense	distal	6	no	7.602	7.482	EPSD	ICGC	2.642	Down-regulation
CMGC_CDK_CDK4_CDK4_ST	P15923	TCF3	P11802	CDK4	T308	G303S	303	Missense	distal	-5	no	7.602	7.830	EPSD	ICGC;COSMIC;CCLE	2.642	Up-regulation
CMGC_CDK_CDK4_CDK4_ST	P15923	TCF3	P11802	CDK4	S312	A314V	314	Missense	proximal	2	no	3.102	2.925	EPSD	ICGC	2.642	Down-regulation
CMGC_CDK_CDK4_CDK4_ST	P15923	TCF3	P11802	CDK4	S352	S359C	359	Missense	distal	7	no	8.901	8.876	EPSD	ICGC	2.642	Down-regulation
CMGC_CDK_CDK4_CDK4_ST	P15923	TCF3	P11802	CDK4	S352	S359F	359	Missense	distal	7	no	8.901	8.876	EPSD	ICGC;COSMIC	2.642	Down-regulation
CMGC_CDK_CDK4_CDK4_ST	P15923	TCF3	P11802	CDK4	T355	S359C	359	Missense	distal	4	no	7.412	7.807	EPSD	ICGC	2.642	Up-regulation
CMGC_CDK_CDK4_CDK4_ST	P15923	TCF3	P11802	CDK4	T355	S359F	359	Missense	distal	4	no	7.412	7.810	EPSD	ICGC;COSMIC	2.642	Up-regulation
CMGC_CDK_CDK4_CDK4_ST	P15923	TCF3	P11802	CDK4	S359	S359C	359	Missense	central	0	yes	8.056	0.000	EPSD	ICGC	2.642	Loss
CMGC_CDK_CDK4_CDK4_ST	P15923	TCF3	P11802	CDK4	S359	S359F	359	Missense	central	0	yes	8.056	0.000	EPSD	ICGC;COSMIC	2.642	Loss
CMGC_CDK_CDK4_CDK4_ST	P15923	TCF3	P11802	CDK4	S379	D383Y	383	Missense	distal	4	no	8.806	8.722	EPSD	ICGC;COSMIC	2.642	Down-regulation
CMGC_CDK_CDK4_CDK4_ST	P15923	TCF3	P11802	CDK4	S379	L386I	386	Missense	distal	7	no	8.806	8.805	EPSD	ICGC;COSMIC	2.642	Down-regulation
CMGC_CDK_CDK4_CDK4_ST	P15923	TCF3	P11802	CDK4	S391	L386I	386	Missense	distal	-5	no	2.909	2.924	EPSD	ICGC;COSMIC	2.642	Up-regulation
CMGC_CDK_CDK4_CDK4_ST	P15923	TCF3	P11802	CDK4	T508	E505K	505	Missense	distal	-3	no	2.885	2.855	EPSD	ICGC;COSMIC	2.642	Down-regulation
CMGC_CDK_CDK4_CDK4_ST	P15923	TCF3	P11802	CDK4	T508	E515K	515	Missense	distal	7	no	2.885	2.887	EPSD	ICGC	2.642	Up-regulation
CMGC_CDK_CDK4_CDK4_ST	P15923	TCF3	P11802	CDK4	T508	A511V	511	Missense	distal	3	no	2.885	2.461	EPSD	ICGC;COSMIC	2.642	Loss
CMGC_CDK_CDK4_CDK4_ST	P15923	TCF3	P11802	CDK4	S529	A523P	523	Missense	distal	-6	no	8.297	8.407	EPSD	ICGC;COSMIC	2.642	Up-regulation
CMGC_CDK_CDK4_CDK4_ST	P15923	TCF3	P11802	CDK4	S529	D536E	536	Missense	distal	7	no	8.297	8.307	EPSD	ICGC	2.642	Up-regulation
CMGC_CDK_CDK4_CDK4_ST	Q9BQA1	WDR77	P11802	CDK4	S142	G137S	137	Missense	distal	-5	no	3.521	3.749	EPSD	ICGC;COSMIC	2.642	Up-regulation
CMGC_CDK_CDK4_CDK4_ST	Q9BQA1	WDR77	P11802	CDK4	S176	V173F	173	Missense	distal	-3	no	7.834	7.805	EPSD	ICGC	2.642	Down-regulation
CMGC_CDK_CDK4_CDK4_ST	Q9BQA1	WDR77	P11802	CDK4	S264	V262I	262	Missense	proximal	-2	no	9.198	9.192	PhosphoSitePlus;EPSD	ICGC	2.642	Down-regulation
CMGC_CDK_CDK4_CDK4_ST	P55072	VCP	P11802	CDK4	S101	I102S	102	Missense	proximal	1	no	1.449	2.785	EPSD	ICGC	2.642	Gain
CMGC_CDK_CDK4_CDK4_ST	P55072	VCP	P11802	CDK4	S171	S171R	171	Missense	central	0	yes	7.349	0.000	EPSD	ICGC	2.642	Loss
CMGC_CDK_CDK4_CDK4_ST	P55072	VCP	P11802	CDK4	S171	D169Y	169	Missense	proximal	-2	no	7.349	7.399	EPSD	ICGC	2.642	Up-regulation
CMGC_CDK_CDK4_CDK4_ST	P55072	VCP	P11802	CDK4	S664	P665T	665	Missense	proximal	1	no	6.758	0.231	PhosphoSitePlus;EPSD	ICGC;COSMIC	2.642	Loss
CMGC_CDK_CDK4_CDK4_ST	P55072	VCP	P11802	CDK4	S683	K677E	677	Missense	distal	-6	no	3.141	3.119	EPSD	ICGC;COSMIC	2.642	Down-regulation
CMGC_CDK_CDK4_CDK4_ST	Q92830	KAT2A	P11802	CDK4	T9	P16L	16	Missense	distal	7	no	7.199	7.182	EPSD	ICGC	2.642	Down-regulation
CMGC_CDK_CDK4_CDK4_ST	Q92830	KAT2A	P11802	CDK4	T9	A11G	11	Missense	proximal	2	no	7.199	6.863	EPSD	ICGC	2.642	Down-regulation
CMGC_CDK_CDK4_CDK4_ST	Q92830	KAT2A	P11802	CDK4	S33	A31T	31	Missense	proximal	-2	no	7.601	7.579	EPSD	ICGC;COSMIC	2.642	Down-regulation
CMGC_CDK_CDK4_CDK4_ST	Q92830	KAT2A	P11802	CDK4	S82	Q85K	85	Missense	distal	3	no	2.356	2.713	EPSD	ICGC	2.642	Gain
CMGC_CDK_CDK4_CDK4_ST	Q92830	KAT2A	P11802	CDK4	T272	P273S	273	Missense	proximal	1	no	7.909	1.722	EPSD;PhosphoSitePlus	ICGC;COSMIC	2.642	Loss
CMGC_CDK_CDK4_CDK4_ST	Q92830	KAT2A	P11802	CDK4	T272	R277L	277	Missense	distal	5	no	7.909	7.923	EPSD;PhosphoSitePlus	ICGC;COSMIC	2.642	Up-regulation
CMGC_CDK_CDK4_CDK4_ST	Q92830	KAT2A	P11802	CDK4	S415	S415R	415	Missense	central	0	yes	3.333	0.000	EPSD	ICGC	2.642	Loss
CMGC_CDK_CDK4_CDK4_ST	Q92830	KAT2A	P11802	CDK4	S415	G413V	413	Missense	proximal	-2	no	3.333	3.303	EPSD	ICGC;COSMIC	2.642	Down-regulation
CMGC_CDK_CDK4_CDK4_ST	P46527	CDKN1B	P11802	CDK4	S10	N8K	8	Missense	proximal	-2	no	7.994	8.023	EPSD	ICGC;COSMIC	2.642	Up-regulation
CMGC_CDK_CDK4_CDK4_ST	P46527	CDKN1B	P11802	CDK4	S178	V184M	184	Missense	distal	6	no	7.626	7.637	EPSD	ICGC;COSMIC	2.642	Up-regulation
CMGC_CDK_CDK4_CDK4_ST	P46527	CDKN1B	P11802	CDK4	S178	G182C	182	Missense	distal	4	no	7.626	7.453	EPSD	ICGC	2.642	Down-regulation
CMGC_CDK_CDK4_CDK4_ST	P46527	CDKN1B	P11802	CDK4	S178	G177V	177	Missense	proximal	-1	no	7.626	7.424	EPSD	ICGC	2.642	Down-regulation
CMGC_CDK_CDK4_CDK4_ST	P46527	CDKN1B	P11802	CDK4	S178	S178F	178	Missense	central	0	yes	7.626	0.000	EPSD	ICGC;COSMIC	2.642	Loss
CMGC_CDK_CDK4_CDK4_ST	P46527	CDKN1B	P11802	CDK4	T187	V184M	184	Missense	distal	-3	no	6.369	6.351	EPSD	ICGC;COSMIC	2.642	Down-regulation
CMGC_CDK_CDK4_CDK4_ST	P46527	CDKN1B	P11802	CDK4	T187	G192V	192	Missense	distal	5	no	6.369	6.363	EPSD	ICGC	2.642	Down-regulation
CMGC_CDK_CDK4_CDK4_ST	P46527	CDKN1B	P11802	CDK4	T187	G182C	182	Missense	distal	-5	no	6.369	6.438	EPSD	ICGC	2.642	Up-regulation
CMGC_CDK_CDK4_CDK4_ST	P46527	CDKN1B	P11802	CDK4	T187	P191H	191	Missense	distal	4	no	6.369	6.512	EPSD	ICGC;COSMIC	2.642	Up-regulation
CMGC_CDK_CDK4_CDK4_ST	P21333	FLNA	P11802	CDK4	S204	P211H	211	Missense	distal	7	no	2.917	2.904	EPSD	ICGC	2.642	Down-regulation
CMGC_CDK_CDK4_CDK4_ST	P21333	FLNA	P11802	CDK4	S468	P464L	464	Missense	distal	-4	no	8.346	8.347	EPSD	ICGC	2.642	Up-regulation
CMGC_CDK_CDK4_CDK4_ST	P21333	FLNA	P11802	CDK4	S468	G475C	475	Missense	distal	7	no	8.346	8.355	EPSD	ICGC;COSMIC	2.642	Up-regulation
CMGC_CDK_CDK4_CDK4_ST	P21333	FLNA	P11802	CDK4	S512	G511V	511	Missense	proximal	-1	no	2.809	2.606	EPSD	ICGC	2.642	Loss
CMGC_CDK_CDK4_CDK4_ST	P21333	FLNA	P11802	CDK4	S512	T518N	518	Missense	distal	6	no	2.809	2.791	EPSD	ICGC;COSMIC	2.642	Down-regulation
CMGC_CDK_CDK4_CDK4_ST	P21333	FLNA	P11802	CDK4	S512	V505M	505	Missense	distal	-7	no	2.809	2.886	EPSD	ICGC	2.642	Up-regulation
CMGC_CDK_CDK4_CDK4_ST	P21333	FLNA	P11802	CDK4	S564	G571A	571	Missense	distal	7	no	7.395	7.420	EPSD	ICGC;COSMIC	2.642	Up-regulation
CMGC_CDK_CDK4_CDK4_ST	P21333	FLNA	P11802	CDK4	S657	E652K	652	Missense	distal	-5	no	7.746	7.733	EPSD	ICGC;COSMIC	2.642	Down-regulation
CMGC_CDK_CDK4_CDK4_ST	P21333	FLNA	P11802	CDK4	S657	R655S	655	Missense	proximal	-2	no	7.746	7.861	EPSD	ICGC;COSMIC	2.642	Up-regulation
CMGC_CDK_CDK4_CDK4_ST	P21333	FLNA	P11802	CDK4	S757	N762D	762	Missense	distal	5	no	8.237	8.251	EPSD	ICGC;COSMIC	2.642	Up-regulation
CMGC_CDK_CDK4_CDK4_ST	P21333	FLNA	P11802	CDK4	T857	R863Q	863	Missense	distal	6	no	6.955	6.908	EPSD	ICGC;COSMIC	2.642	Down-regulation
CMGC_CDK_CDK4_CDK4_ST	P21333	FLNA	P11802	CDK4	T857	P861T	861	Missense	distal	4	no	6.955	6.976	EPSD	ICGC;COSMIC	2.642	Up-regulation
CMGC_CDK_CDK4_CDK4_ST	P21333	FLNA	P11802	CDK4	T857	T859N	859	Missense	proximal	2	no	6.955	6.960	EPSD	ICGC;COSMIC	2.642	Up-regulation
CMGC_CDK_CDK4_CDK4_ST	P21333	FLNA	P11802	CDK4	S860	R863Q	863	Missense	distal	3	no	8.518	8.169	EPSD	ICGC;COSMIC	2.642	Down-regulation
CMGC_CDK_CDK4_CDK4_ST	P21333	FLNA	P11802	CDK4	S860	P861T	861	Missense	proximal	1	no	8.518	1.991	EPSD	ICGC;COSMIC	2.642	Loss
CMGC_CDK_CDK4_CDK4_ST	P21333	FLNA	P11802	CDK4	S860	T859N	859	Missense	proximal	-1	no	8.518	8.509	EPSD	ICGC;COSMIC	2.642	Down-regulation
CMGC_CDK_CDK4_CDK4_ST	P21333	FLNA	P11802	CDK4	T938	Y933F	933	Missense	distal	-5	no	6.102	6.057	EPSD	ICGC	2.642	Down-regulation
CMGC_CDK_CDK4_CDK4_ST	P21333	FLNA	P11802	CDK4	T938	Q941K	941	Missense	distal	3	no	6.102	6.460	EPSD	ICGC;COSMIC	2.642	Up-regulation
CMGC_CDK_CDK4_CDK4_ST	P21333	FLNA	P11802	CDK4	T938	N931K	931	Missense	distal	-7	no	6.102	6.142	EPSD	ICGC	2.642	Up-regulation
CMGC_CDK_CDK4_CDK4_ST	P21333	FLNA	P11802	CDK4	S959	P955H	955	Missense	distal	-4	no	8.279	8.280	EPSD	ICGC;COSMIC	2.642	Up-regulation
CMGC_CDK_CDK4_CDK4_ST	P21333	FLNA	P11802	CDK4	S959	G953V	953	Missense	distal	-6	no	8.279	8.087	EPSD	ICGC;COSMIC	2.642	Down-regulation
CMGC_CDK_CDK4_CDK4_ST	P21333	FLNA	P11802	CDK4	S1055	P1056H	1056	Missense	proximal	1	no	9.441	2.858	EPSD	ICGC;COSMIC	2.642	Down-regulation
CMGC_CDK_CDK4_CDK4_ST	P21333	FLNA	P11802	CDK4	S1055	V1052M	1052	Missense	distal	-3	no	9.441	9.423	EPSD	ICGC;COSMIC;GDSC;CCLE	2.642	Down-regulation
CMGC_CDK_CDK4_CDK4_ST	P21333	FLNA	P11802	CDK4	S1055	G1049S	1049	Missense	distal	-6	no	9.441	8.894	EPSD	ICGC;COSMIC	2.642	Down-regulation
CMGC_CDK_CDK4_CDK4_ST	P21333	FLNA	P11802	CDK4	T1322	P1323T	1323	Missense	proximal	1	no	6.321	-0.205	EPSD	ICGC;COSMIC	2.642	Loss
CMGC_CDK_CDK4_CDK4_ST	P21333	FLNA	P11802	CDK4	S1343	V1349M	1349	Missense	distal	6	no	7.959	7.971	EPSD	ICGC;COSMIC	2.642	Up-regulation
CMGC_CDK_CDK4_CDK4_ST	P21333	FLNA	P11802	CDK4	S1436	G1430S	1430	Missense	distal	-6	no	8.728	8.181	EPSD	ICGC;COSMIC	2.642	Down-regulation
CMGC_CDK_CDK4_CDK4_ST	P21333	FLNA	P11802	CDK4	S1459	R1464S	1464	Missense	distal	5	no	7.700	7.678	EPSD;PhosphoSitePlus	ICGC	2.642	Down-regulation
CMGC_CDK_CDK4_CDK4_ST	P21333	FLNA	P11802	CDK4	S1533	P1531T	1531	Missense	proximal	-2	no	8.319	7.898	EPSD	ICGC	2.642	Down-regulation
CMGC_CDK_CDK4_CDK4_ST	P21333	FLNA	P11802	CDK4	S1630	G1623V	1623	Missense	distal	-7	no	8.722	8.934	EPSD	ICGC;COSMIC	2.642	Up-regulation
CMGC_CDK_CDK4_CDK4_ST	P21333	FLNA	P11802	CDK4	S1630	R1633S	1633	Missense	distal	3	no	8.722	8.964	EPSD	ICGC	2.642	Up-regulation
CMGC_CDK_CDK4_CDK4_ST	P21333	FLNA	P11802	CDK4	S1946	R1951C	1951	Missense	distal	5	no	8.552	8.568	EPSD	ICGC;COSMIC	2.642	Up-regulation
CMGC_CDK_CDK4_CDK4_ST	P21333	FLNA	P11802	CDK4	S1961	R1959H	1959	Missense	proximal	-2	no	2.732	2.697	EPSD	ICGC;COSMIC	2.642	Down-regulation
CMGC_CDK_CDK4_CDK4_ST	P21333	FLNA	P11802	CDK4	S2033	S2032R	2032	Missense	proximal	-1	no	10.465	10.610	EPSD	ICGC;COSMIC	2.642	Up-regulation
CMGC_CDK_CDK4_CDK4_ST	P21333	FLNA	P11802	CDK4	S2319	P2320L	2320	Missense	proximal	1	no	8.717	1.137	EPSD	ICGC;COSMIC	2.642	Loss
CMGC_CDK_CDK4_CDK4_ST	P21333	FLNA	P11802	CDK4	S2327	P2320L	2320	Missense	distal	-7	no	6.517	6.037	EPSD	ICGC;COSMIC	2.642	Down-regulation
CMGC_CDK_CDK4_CDK4_ST	P21333	FLNA	P11802	CDK4	S2414	P2415L	2415	Missense	proximal	1	no	10.927	3.348	EPSD	ICGC	2.642	Down-regulation
CMGC_CDK_CDK4_CDK4_ST	P21333	FLNA	P11802	CDK4	T2599	T2599N	2599	Missense	central	0	yes	7.664	0.000	EPSD	ICGC;COSMIC	2.642	Loss
CMGC_CDK_CDK4_CDK4_ST	P21333	FLNA	P11802	CDK4	S2640	P2638T	2638	Missense	proximal	-2	no	8.982	8.560	EPSD	ICGC;COSMIC	2.642	Down-regulation
CMGC_CDK_CDK4_CDK4_ST	P04179	SOD2	P11802	CDK4	S106	G109D	109	Missense	distal	3	no	7.812	7.801	PhosphoSitePlus	ICGC;COSMIC	2.642	Down-regulation
CMGC_CDK_CDK4_CDK4_ST	O15151	MDM4	P11802	CDK4	S20	S20F	20	Missense	central	0	yes	8.538	0.000	EPSD	ICGC;COSMIC	2.642	Loss
CMGC_CDK_CDK4_CDK4_ST	O15151	MDM4	P11802	CDK4	S96	D100G	100	Missense	distal	4	no	7.900	8.075	EPSD	ICGC;COSMIC	2.642	Up-regulation
CMGC_CDK_CDK4_CDK4_ST	Q13761	RUNX3	P11802	CDK4	S71	E65Q	65	Missense	distal	-6	no	7.041	7.107	EPSD	ICGC;COSMIC	2.642	Up-regulation
CMGC_CDK_CDK4_CDK4_ST	Q13761	RUNX3	P11802	CDK4	T231	S237R	237	Missense	distal	6	no	6.894	6.783	EPSD	ICGC;COSMIC	2.642	Down-regulation
CMGC_CDK_CDK4_CDK4_ST	Q13761	RUNX3	P11802	CDK4	S243	S237R	237	Missense	distal	-6	no	3.015	3.286	EPSD	ICGC;COSMIC	2.642	Up-regulation
CMGC_CDK_CDK4_CDK4_ST	Q92879	CELF1	P11802	CDK4	S178	V183G	183	Missense	distal	5	no	2.636	2.642	EPSD	ICGC;COSMIC	2.642	Gain
CMGC_CDK_CDK4_CDK4_ST	Q92879	CELF1	P11802	CDK4	S179	Q172K	172	Missense	distal	-7	no	6.729	6.847	EPSD	ICGC	2.642	Up-regulation
CMGC_CDK_CDK4_CDK4_ST	Q92879	CELF1	P11802	CDK4	S179	V183G	183	Missense	distal	4	no	6.729	6.908	EPSD	ICGC;COSMIC	2.642	Up-regulation
CMGC_CDK_CDK4_CDK4_ST	Q92879	CELF1	P11802	CDK4	S179	V183L	183	Missense	distal	4	no	6.729	6.707	EPSD	ICGC	2.642	Down-regulation
CMGC_CDK_CDK4_CDK4_ST	Q92879	CELF1	P11802	CDK4	S179	A186V	186	Missense	distal	7	no	6.729	6.714	EPSD	ICGC;COSMIC	2.642	Down-regulation
CMGC_CDK_CDK4_CDK4_ST	Q92879	CELF1	P11802	CDK4	S241	S248R	248	Missense	distal	7	no	3.150	3.135	EPSD	ICGC	2.642	Down-regulation
CMGC_CDK_CDK4_CDK4_ST	Q92879	CELF1	P11802	CDK4	S241	L244I	244	Missense	distal	3	no	3.150	2.926	EPSD	ICGC	2.642	Down-regulation
CMGC_CDK_CDK4_CDK4_ST	Q92879	CELF1	P11802	CDK4	S297	S299L	299	Missense	proximal	2	no	3.097	2.870	EPSD	ICGC;COSMIC	2.642	Down-regulation
CMGC_CDK_CDK4_CDK4_ST	Q92879	CELF1	P11802	CDK4	S299	S299L	299	Missense	central	0	yes	2.705	0.000	EPSD	ICGC;COSMIC	2.642	Loss
CMGC_CDK_CDK4_CDK4_ST	Q92879	CELF1	P11802	CDK4	S300	S299L	299	Missense	proximal	-1	no	6.987	7.272	EPSD	ICGC;COSMIC	2.642	Up-regulation
CMGC_CDK_CDK4_CDK4_ST	Q92879	CELF1	P11802	CDK4	S302	S299L	299	Missense	distal	-3	no	4.128	4.311	PhosphoSitePlus	ICGC;COSMIC	2.642	Up-regulation
CMGC_CDK_CDK4_CDK4_ST	P04637	TP53	P11802	CDK4	S33	P34L	34	Missense	proximal	1	no	7.064	-0.515	EPSD	ICGC;COSMIC	2.642	Loss
CMGC_CDK_CDK4_CDK4_ST	P04637	TP53	P11802	CDK4	S33	S33F	33	Missense	central	0	yes	7.064	0.000	EPSD	ICGC;COSMIC	2.642	Loss
CMGC_CDK_CDK4_CDK4_ST	P04637	TP53	P11802	CDK4	S33	N30I	30	Missense	distal	-3	no	7.064	7.150	EPSD	ICGC	2.642	Up-regulation
CMGC_CDK_CDK4_CDK4_ST	P04637	TP53	P11802	CDK4	S46	D48G	48	Missense	proximal	2	no	6.809	6.651	EPSD	ICGC;COSMIC	2.642	Down-regulation
CMGC_CDK_CDK4_CDK4_ST	P04637	TP53	P11802	CDK4	S46	Q52K	52	Missense	distal	6	no	6.809	6.877	EPSD	ICGC	2.642	Up-regulation
CMGC_CDK_CDK4_CDK4_ST	P04637	TP53	P11802	CDK4	T81	A88D	88	Missense	distal	7	no	8.060	8.045	EPSD	ICGC	2.642	Down-regulation
CMGC_CDK_CDK4_CDK4_ST	P04637	TP53	P11802	CDK4	T81	P87Q	87	Missense	distal	6	no	8.060	8.059	EPSD	ICGC;COSMIC	2.642	Down-regulation
CMGC_CDK_CDK4_CDK4_ST	P04637	TP53	P11802	CDK4	S99	Q100K	100	Missense	proximal	1	no	2.211	2.752	EPSD	ICGC;COSMIC	2.642	Gain
CMGC_CDK_CDK4_CDK4_ST	P04637	TP53	P11802	CDK4	S127	T125R	125	Missense	proximal	-2	no	7.138	7.139	EPSD	ICGC;COSMIC	2.642	Up-regulation
CMGC_CDK_CDK4_CDK4_ST	P04637	TP53	P11802	CDK4	S127	C124G	124	Missense	distal	-3	no	7.138	7.187	EPSD	ICGC;COSMIC	2.642	Up-regulation
CMGC_CDK_CDK4_CDK4_ST	P04637	TP53	P11802	CDK4	S127	C124R	124	Missense	distal	-3	no	7.138	7.069	EPSD	ICGC;COSMIC;GDSC;CCLE	2.642	Down-regulation
CMGC_CDK_CDK4_CDK4_ST	P04637	TP53	P11802	CDK4	S127	L130H	130	Missense	distal	3	no	7.138	7.124	EPSD	ICGC;COSMIC	2.642	Down-regulation
CMGC_CDK_CDK4_CDK4_ST	P04637	TP53	P11802	CDK4	S127	T125A	125	Missense	proximal	-2	no	7.138	7.160	EPSD	ICGC;COSMIC	2.642	Up-regulation
CMGC_CDK_CDK4_CDK4_ST	P04637	TP53	P11802	CDK4	S127	K120N	120	Missense	distal	-7	no	7.138	7.099	EPSD	ICGC;COSMIC;GDSC;CCLE	2.642	Down-regulation
CMGC_CDK_CDK4_CDK4_ST	P04637	TP53	P11802	CDK4	S127	N131Y	131	Missense	distal	4	no	7.138	7.220	EPSD	ICGC;COSMIC	2.642	Up-regulation
CMGC_CDK_CDK4_CDK4_ST	P04637	TP53	P11802	CDK4	S127	K120M	120	Missense	distal	-7	no	7.138	6.942	EPSD	ICGC;COSMIC	2.642	Down-regulation
CMGC_CDK_CDK4_CDK4_ST	P04637	TP53	P11802	CDK4	S127	K132M	132	Missense	distal	5	no	7.138	7.152	EPSD	ICGC;COSMIC;CCLE	2.642	Up-regulation
CMGC_CDK_CDK4_CDK4_ST	P04637	TP53	P11802	CDK4	S127	M133T	133	Missense	distal	6	no	7.138	7.203	EPSD	ICGC;COSMIC	2.642	Up-regulation
CMGC_CDK_CDK4_CDK4_ST	P04637	TP53	P11802	CDK4	S127	K120R	120	Missense	distal	-7	no	7.138	7.079	EPSD	ICGC;COSMIC	2.642	Down-regulation
CMGC_CDK_CDK4_CDK4_ST	P04637	TP53	P11802	CDK4	S127	C124Y	124	Missense	distal	-3	no	7.138	7.099	EPSD	ICGC;COSMIC	2.642	Down-regulation
CMGC_CDK_CDK4_CDK4_ST	P04637	TP53	P11802	CDK4	T150	R156L	156	Missense	distal	6	no	7.199	7.131	EPSD	ICGC;COSMIC	2.642	Down-regulation
CMGC_CDK_CDK4_CDK4_ST	P04637	TP53	P11802	CDK4	T150	L145Q	145	Missense	distal	-5	no	7.199	7.238	EPSD	ICGC;COSMIC	2.642	Up-regulation
CMGC_CDK_CDK4_CDK4_ST	P04637	TP53	P11802	CDK4	T150	P152R	152	Missense	proximal	2	no	7.199	7.236	EPSD	ICGC;COSMIC	2.642	Up-regulation
CMGC_CDK_CDK4_CDK4_ST	P04637	TP53	P11802	CDK4	T150	G154S	154	Missense	distal	4	no	7.199	6.631	EPSD	ICGC;COSMIC	2.642	Down-regulation
CMGC_CDK_CDK4_CDK4_ST	P04637	TP53	P11802	CDK4	T150	V157A	157	Missense	distal	7	no	7.199	7.214	EPSD	ICGC;COSMIC	2.642	Up-regulation
CMGC_CDK_CDK4_CDK4_ST	P04637	TP53	P11802	CDK4	T150	P151F	151	Missense	proximal	1	no	7.199	1.534	EPSD	ICGC;COSMIC	2.642	Loss
CMGC_CDK_CDK4_CDK4_ST	P04637	TP53	P11802	CDK4	T150	V147G	147	Missense	distal	-3	no	7.199	7.246	EPSD	ICGC;COSMIC;GDSC;CCLE	2.642	Up-regulation
CMGC_CDK_CDK4_CDK4_ST	P04637	TP53	P11802	CDK4	S315	T312I	312	Missense	distal	-3	no	8.449	8.537	EPSD	ICGC;COSMIC	2.642	Up-regulation
CMGC_CDK_CDK4_CDK4_ST	P04637	TP53	P11802	CDK4	S315	P322T	322	Missense	distal	7	no	8.449	8.442	EPSD	ICGC	2.642	Down-regulation
CMGC_CDK_CDK4_CDK4_ST	P04637	TP53	P11802	CDK4	S376	T377P	377	Missense	proximal	1	no	1.534	8.060	EPSD	ICGC;COSMIC	2.642	Gain
CMGC_CDK_CDK4_CDK4_ST	P28749	RBL1	P11802	CDK4	T332	D325E	325	Missense	distal	-7	no	7.964	8.194	EPSD	ICGC	2.642	Up-regulation
CMGC_CDK_CDK4_CDK4_ST	P28749	RBL1	P11802	CDK4	T385	A388E	388	Missense	distal	3	no	6.496	6.304	EPSD	ICGC	2.642	Down-regulation
CMGC_CDK_CDK4_CDK4_ST	P28749	RBL1	P11802	CDK4	S615	P613S	613	Missense	proximal	-2	no	7.431	7.126	EPSD	ICGC	2.642	Down-regulation
CMGC_CDK_CDK4_CDK4_ST	P28749	RBL1	P11802	CDK4	S615	P613Q	613	Missense	proximal	-2	no	7.431	6.951	EPSD	ICGC	2.642	Down-regulation
CMGC_CDK_CDK4_CDK4_ST	P28749	RBL1	P11802	CDK4	S615	M614I	614	Missense	proximal	-1	no	7.431	7.457	EPSD	ICGC;COSMIC	2.642	Up-regulation
CMGC_CDK_CDK4_CDK4_ST	P28749	RBL1	P11802	CDK4	S749	E744G	744	Missense	distal	-5	no	7.445	7.296	EPSD	ICGC;COSMIC	2.642	Down-regulation
CMGC_CDK_CDK4_CDK4_ST	P28749	RBL1	P11802	CDK4	S762	N767S	767	Missense	distal	5	no	6.469	6.445	EPSD	ICGC;COSMIC	2.642	Down-regulation
CMGC_CDK_CDK4_CDK4_ST	P28749	RBL1	P11802	CDK4	T915	C918F	918	Missense	distal	3	no	6.714	6.805	EPSD	ICGC;COSMIC	2.642	Up-regulation
CMGC_CDK_CDK4_CDK4_ST	P28749	RBL1	P11802	CDK4	T915	P922T	922	Missense	distal	7	no	6.714	6.707	EPSD	ICGC	2.642	Down-regulation
CMGC_CDK_CDK4_CDK4_ST	P28749	RBL1	P11802	CDK4	S964	P967Q	967	Missense	distal	3	no	8.450	7.555	PhosphoSitePlus;EPSD	ICGC;COSMIC	2.642	Down-regulation
CMGC_CDK_CDK4_CDK4_ST	P28749	RBL1	P11802	CDK4	S964	L963I	963	Missense	proximal	-1	no	8.450	8.477	PhosphoSitePlus;EPSD	ICGC	2.642	Up-regulation
CMGC_CDK_CDK4_CDK4_ST	P28749	RBL1	P11802	CDK4	S964	P961L	961	Missense	distal	-3	no	8.450	8.707	PhosphoSitePlus;EPSD	ICGC;COSMIC	2.642	Up-regulation
CMGC_CDK_CDK4_CDK4_ST	P28749	RBL1	P11802	CDK4	S975	S975L	975	Missense	central	0	yes	7.914	0.000	EPSD;PhosphoSitePlus	ICGC;COSMIC	2.642	Loss
CMGC_CDK_CDK4_CDK4_ST	P28749	RBL1	P11802	CDK4	S975	R977H	977	Missense	proximal	2	no	7.914	7.787	EPSD;PhosphoSitePlus	ICGC	2.642	Down-regulation
CMGC_CDK_CDK4_CDK4_ST	P28749	RBL1	P11802	CDK4	S988	G995V	995	Missense	distal	7	no	5.437	5.446	EPSD	ICGC;COSMIC	2.642	Up-regulation
CMGC_CDK_CDK4_CDK4_ST	P28749	RBL1	P11802	CDK4	S988	P989Q	989	Missense	proximal	1	no	5.437	-1.732	EPSD	ICGC	2.642	Loss
CMGC_CDK_CDK4_CDK4_ST	P28749	RBL1	P11802	CDK4	S994	G995V	995	Missense	proximal	1	no	3.474	1.947	EPSD	ICGC;COSMIC	2.642	Loss
CMGC_CDK_CDK4_CDK4_ST	P28749	RBL1	P11802	CDK4	S994	P989Q	989	Missense	distal	-5	no	3.474	3.499	EPSD	ICGC	2.642	Up-regulation
CMGC_CDK_CDK4_CDK4_ST	P28749	RBL1	P11802	CDK4	S994	A1001D	1001	Missense	distal	7	no	3.474	3.459	EPSD	ICGC	2.642	Down-regulation
CMGC_CDK_CDK4_CDK4_ST	P28749	RBL1	P11802	CDK4	S994	S1000R	1000	Missense	distal	6	no	3.474	3.363	EPSD	ICGC;COSMIC	2.642	Down-regulation
CMGC_CDK_CDK4_CDK4_ST	P28749	RBL1	P11802	CDK4	T997	L1002V	1002	Missense	distal	5	no	6.149	6.153	EPSD	ICGC;COSMIC	2.642	Up-regulation
CMGC_CDK_CDK4_CDK4_ST	P28749	RBL1	P11802	CDK4	T997	G995V	995	Missense	proximal	-2	no	6.149	6.118	EPSD	ICGC;COSMIC	2.642	Down-regulation
CMGC_CDK_CDK4_CDK4_ST	P28749	RBL1	P11802	CDK4	T997	A1001D	1001	Missense	distal	4	no	6.149	6.449	EPSD	ICGC	2.642	Up-regulation
CMGC_CDK_CDK4_CDK4_ST	P28749	RBL1	P11802	CDK4	T997	S1000R	1000	Missense	distal	3	no	6.149	5.907	EPSD	ICGC;COSMIC	2.642	Down-regulation
CMGC_CDK_CDK4_CDK4_ST	P28749	RBL1	P11802	CDK4	S1009	L1002V	1002	Missense	distal	-7	no	7.843	7.821	EPSD	ICGC;COSMIC	2.642	Down-regulation
CMGC_CDK_CDK4_CDK4_ST	P28749	RBL1	P11802	CDK4	S1009	S1009R	1009	Missense	central	0	yes	7.843	0.000	EPSD	ICGC	2.642	Loss
CMGC_CDK_CDK4_CDK4_ST	P28749	RBL1	P11802	CDK4	S1009	K1012E	1012	Missense	distal	3	no	7.843	7.555	EPSD	ICGC;COSMIC	2.642	Down-regulation
CMGC_CDK_CDK4_CDK4_ST	P28749	RBL1	P11802	CDK4	S1041	R1045H	1045	Missense	distal	4	no	8.778	8.897	EPSD	ICGC	2.642	Up-regulation
CMGC_CDK_CDK4_CDK4_ST	P28749	RBL1	P11802	CDK4	S1041	A1034D	1034	Missense	distal	-7	no	8.778	8.380	EPSD	ICGC;COSMIC	2.642	Down-regulation
CMGC_CDK_CDK4_CDK4_ST	P28749	RBL1	P11802	CDK4	S1041	I1035V	1035	Missense	distal	-6	no	8.778	8.766	EPSD	ICGC;COSMIC	2.642	Down-regulation
CMGC_CDK_CDK4_CDK4_ST	P28749	RBL1	P11802	CDK4	S1041	C1047F	1047	Missense	distal	6	no	8.778	8.771	EPSD	ICGC	2.642	Down-regulation
CMGC_CDK_CDK4_CDK4_ST	O43791	SPOP	P11802	CDK4	S6	P7T	7	Missense	proximal	1	no	8.610	2.083	PhosphoSitePlus	ICGC	2.642	Loss
CMGC_CDK_CDK4_CDK4_ST	O43791	SPOP	P11802	CDK4	S6	P10S	10	Missense	distal	4	no	8.610	8.403	PhosphoSitePlus	ICGC;COSMIC	2.642	Down-regulation
CMGC_CDK_CDK4_CDK4_ST	O43791	SPOP	P11802	CDK4	S6	P8S	8	Missense	proximal	2	no	8.610	8.768	PhosphoSitePlus	ICGC;COSMIC	2.642	Up-regulation
STE_STE11_MEKK2_MAP3K3_ST	P08151	GLI1	Q99759	MAP3K3	S69	C62Y	62	Missense	distal	-7	no	12.155	11.543	EPSD	ICGC	11.002	Down-regulation
STE_STE11_MEKK2_MAP3K3_ST	P53805	RCAN1	Q99759	MAP3K3	S163	P168T	168	Missense	distal	5	no	28.012	26.906	PhosphoSitePlus;EPSD	ICGC	11.002	Down-regulation
STE_STE11_MEKK2_MAP3K3_ST	P53805	RCAN1	Q99759	MAP3K3	S167	P168T	168	Missense	proximal	1	no	29.082	28.342	EPSD;PhosphoSitePlus	ICGC	11.002	Down-regulation
TKL_STKR_STKR1_TGFBR1_ST	Q03167	TGFBR3	P36897	TGFBR1	S651	S651C	651	Missense	central	0	yes	14.135	0.000	EPSD	ICGC;COSMIC	13.873	Loss
TKL_STKR_STKR1_TGFBR1_ST	Q15796	SMAD2	P36897	TGFBR1	S47	K53N	53	Missense	distal	6	no	13.996	15.047	EPSD	ICGC;COSMIC	13.873	Up-regulation
TKL_STKR_STKR1_TGFBR1_ST	Q15796	SMAD2	P36897	TGFBR1	S110	R109S	109	Missense	proximal	-1	no	13.969	11.966	EPSD	ICGC;COSMIC	13.873	Loss
TKL_STKR_STKR1_TGFBR1_ST	Q15796	SMAD2	P36897	TGFBR1	S110	V117I	117	Missense	distal	7	no	13.969	13.124	EPSD	ICGC	13.873	Loss
TKL_STKR_STKR1_TGFBR1_ST	Q15796	SMAD2	P36897	TGFBR1	S110	S110Y	110	Missense	central	0	yes	13.969	0.000	EPSD	ICGC	13.873	Loss
TKL_STKR_STKR1_TGFBR1_ST	Q15796	SMAD2	P36897	TGFBR1	S110	R109M	109	Missense	proximal	-1	no	13.969	13.606	EPSD	ICGC;COSMIC	13.873	Loss
TKL_STKR_STKR1_TGFBR1_ST	Q15796	SMAD2	P36897	TGFBR1	S110	S105Y	105	Missense	distal	-5	no	13.969	13.946	EPSD	ICGC;COSMIC	13.873	Down-regulation
TKL_STKR_STKR1_TGFBR1_ST	Q15796	SMAD2	P36897	TGFBR1	S110	S103I	103	Missense	distal	-7	no	13.969	10.237	EPSD	ICGC	13.873	Loss
TKL_STKR_STKR1_TGFBR1_ST	Q15796	SMAD2	P36897	TGFBR1	S118	V117I	117	Missense	proximal	-1	no	16.204	17.175	EPSD	ICGC	13.873	Up-regulation
TKL_STKR_STKR1_TGFBR1_ST	Q15796	SMAD2	P36897	TGFBR1	S118	P124Q	124	Missense	distal	6	no	16.204	15.483	EPSD	ICGC	13.873	Down-regulation
TKL_STKR_STKR1_TGFBR1_ST	Q15796	SMAD2	P36897	TGFBR1	S118	H119N	119	Missense	proximal	1	no	16.204	16.231	EPSD	ICGC;COSMIC	13.873	Up-regulation
TKL_STKR_STKR1_TGFBR1_ST	Q15796	SMAD2	P36897	TGFBR1	S118	P124T	124	Missense	distal	6	no	16.204	14.118	EPSD	ICGC	13.873	Down-regulation
TKL_STKR_STKR1_TGFBR1_ST	Q15796	SMAD2	P36897	TGFBR1	T220	T220K	220	Missense	central	0	yes	13.948	0.000	EPSD	ICGC	13.873	Loss
TKL_STKR_STKR1_TGFBR1_ST	Q15796	SMAD2	P36897	TGFBR1	S250	V257F	257	Missense	distal	7	no	15.150	14.579	EPSD	ICGC;COSMIC	13.873	Down-regulation
TKL_STKR_STKR1_TGFBR1_ST	Q15796	SMAD2	P36897	TGFBR1	S260	V257F	257	Missense	distal	-3	no	14.690	14.398	EPSD	ICGC;COSMIC	13.873	Down-regulation
TKL_STKR_STKR1_TGFBR1_ST	P68104	EEF1A1	P36897	TGFBR1	S175	Y177F	177	Missense	proximal	2	no	14.008	13.963	EPSD	ICGC;COSMIC	13.873	Down-regulation
TKL_STKR_STKR1_TGFBR1_ST	P68104	EEF1A1	P36897	TGFBR1	S175	V171A	171	Missense	distal	-4	no	14.008	13.825	EPSD	ICGC;COSMIC	13.873	Loss
TKL_STKR_STKR1_TGFBR1_ST	P68104	EEF1A1	P36897	TGFBR1	S300	L299F	299	Missense	proximal	-1	no	29.072	28.603	PhosphoSitePlus	ICGC;COSMIC	13.873	Down-regulation
TKL_STKR_STKR1_TGFBR1_ST	P68104	EEF1A1	P36897	TGFBR1	S354	A355T	355	Missense	proximal	1	no	15.279	15.150	EPSD	ICGC;COSMIC	13.873	Down-regulation
TKL_STKR_STKR1_TGFBR1_ST	P68104	EEF1A1	P36897	TGFBR1	S354	L347M	347	Missense	distal	-7	no	15.279	15.542	EPSD	ICGC;COSMIC	13.873	Up-regulation
TKL_STKR_STKR1_TGFBR1_ST	Q9H3D4	TP63	P36897	TGFBR1	S68	P65S	65	Missense	distal	-3	no	13.136	14.372	PhosphoSitePlus	ICGC;COSMIC	13.873	Gain
TKL_STKR_STKR1_TGFBR1_ST	Q9H3D4	TP63	P36897	TGFBR1	S160	S154F	154	Missense	distal	-6	no	29.350	30.348	EPSD	ICGC;COSMIC;GDSC;CCLE	13.873	Up-regulation
TKL_STKR_STKR1_TGFBR1_ST	Q9H3D4	TP63	P36897	TGFBR1	S160	P166S	166	Missense	distal	6	no	29.350	29.288	EPSD	ICGC;COSMIC	13.873	Down-regulation
TKL_STKR_STKR1_TGFBR1_ST	Q9H3D4	TP63	P36897	TGFBR1	S160	P161A	161	Missense	proximal	1	no	29.350	29.417	EPSD	ICGC	13.873	Up-regulation
TKL_STKR_STKR1_TGFBR1_ST	Q9H3D4	TP63	P36897	TGFBR1	S160	P161Q	161	Missense	proximal	1	no	29.350	29.231	EPSD	ICGC;COSMIC	13.873	Down-regulation
TKL_STKR_STKR1_TGFBR1_ST	Q9H3D4	TP63	P36897	TGFBR1	S160	S162L	162	Missense	proximal	2	no	29.350	29.107	EPSD	ICGC;COSMIC;GDSC;CCLE	13.873	Down-regulation
TKL_STKR_STKR1_TGFBR1_ST	Q9H3D4	TP63	P36897	TGFBR1	S160	I165T	165	Missense	distal	5	no	29.350	28.024	EPSD	ICGC;COSMIC	13.873	Down-regulation
TKL_STKR_STKR1_TGFBR1_ST	Q9H3D4	TP63	P36897	TGFBR1	S160	D157N	157	Missense	distal	-3	no	29.350	28.970	EPSD	ICGC;COSMIC	13.873	Down-regulation
TKL_STKR_STKR1_TGFBR1_ST	Q9H3D4	TP63	P36897	TGFBR1	S162	P166S	166	Missense	distal	4	no	28.456	28.434	EPSD	ICGC;COSMIC	13.873	Down-regulation
TKL_STKR_STKR1_TGFBR1_ST	Q9H3D4	TP63	P36897	TGFBR1	S162	P161A	161	Missense	proximal	-1	no	28.456	28.386	EPSD	ICGC	13.873	Down-regulation
TKL_STKR_STKR1_TGFBR1_ST	Q9H3D4	TP63	P36897	TGFBR1	S162	P161Q	161	Missense	proximal	-1	no	28.456	27.681	EPSD	ICGC;COSMIC	13.873	Down-regulation
TKL_STKR_STKR1_TGFBR1_ST	Q9H3D4	TP63	P36897	TGFBR1	S162	S162L	162	Missense	central	0	yes	28.456	0.000	EPSD	ICGC;COSMIC;GDSC;CCLE	13.873	Loss
TKL_STKR_STKR1_TGFBR1_ST	Q9H3D4	TP63	P36897	TGFBR1	S162	I165T	165	Missense	distal	3	no	28.456	26.217	EPSD	ICGC;COSMIC	13.873	Down-regulation
TKL_STKR_STKR1_TGFBR1_ST	Q9H3D4	TP63	P36897	TGFBR1	S162	D157N	157	Missense	distal	-5	no	28.456	28.531	EPSD	ICGC;COSMIC	13.873	Up-regulation
TKL_STKR_STKR1_TGFBR1_ST	Q9H3D4	TP63	P36897	TGFBR1	S358	V364F	364	Missense	distal	6	no	13.095	14.614	EPSD	ICGC	13.873	Gain
TKL_STKR_STKR1_TGFBR1_ST	Q9H3D4	TP63	P36897	TGFBR1	S367	T374A	374	Missense	distal	7	no	15.787	16.174	EPSD	ICGC;COSMIC	13.873	Up-regulation
TKL_STKR_STKR1_TGFBR1_ST	Q9H3D4	TP63	P36897	TGFBR1	S367	V364F	364	Missense	distal	-3	no	15.787	15.494	EPSD	ICGC	13.873	Down-regulation
TKL_STKR_STKR1_TGFBR1_ST	Q9H3D4	TP63	P36897	TGFBR1	S367	R360G	360	Missense	distal	-7	no	15.787	16.237	EPSD	ICGC;COSMIC	13.873	Up-regulation
TKL_STKR_STKR1_TGFBR1_ST	P17813	ENG	P36897	TGFBR1	S619	R618S	618	Missense	proximal	-1	no	15.554	13.551	EPSD	ICGC;COSMIC	13.873	Loss
TKL_STKR_STKR1_TGFBR1_ST	Q96FW1	OTUB1	P36897	TGFBR1	S18	A25V	25	Missense	distal	7	no	29.011	28.442	PhosphoSitePlus	ICGC	13.873	Down-regulation
TKL_STKR_STKR1_TGFBR1_ST	Q96FW1	OTUB1	P36897	TGFBR1	S18	A25S	25	Missense	distal	7	no	29.011	29.697	PhosphoSitePlus	ICGC;COSMIC	13.873	Up-regulation
CAMK_MAPKAPK_MK5_MAPKAPK5_ST	O60229	KALRN	Q8IW41	MAPKAPK5	S86	V89M	89	Missense	distal	3	no	29.183	29.348	EPSD	ICGC;COSMIC	23.028	Up-regulation
CAMK_MAPKAPK_MK5_MAPKAPK5_ST	O60229	KALRN	Q8IW41	MAPKAPK5	S86	V84M	84	Missense	proximal	-2	no	29.183	29.152	EPSD	ICGC	23.028	Down-regulation
CAMK_MAPKAPK_MK5_MAPKAPK5_ST	O60229	KALRN	Q8IW41	MAPKAPK5	S86	G93C	93	Missense	distal	7	no	29.183	28.905	EPSD	ICGC;COSMIC	23.028	Down-regulation
CAMK_MAPKAPK_MK5_MAPKAPK5_ST	O60229	KALRN	Q8IW41	MAPKAPK5	S103	G102C	102	Missense	proximal	-1	no	12.737	24.354	EPSD	ICGC;COSMIC	23.028	Gain
CAMK_MAPKAPK_MK5_MAPKAPK5_ST	O60229	KALRN	Q8IW41	MAPKAPK5	S487	S491Y	491	Missense	distal	4	no	48.952	49.057	PhosphoSitePlus	ICGC;COSMIC	23.028	Up-regulation
CAMK_MAPKAPK_MK5_MAPKAPK5_ST	O60229	KALRN	Q8IW41	MAPKAPK5	S487	S493P	493	Missense	distal	6	no	48.952	49.074	PhosphoSitePlus	ICGC;COSMIC	23.028	Up-regulation
CAMK_MAPKAPK_MK5_MAPKAPK5_ST	O60229	KALRN	Q8IW41	MAPKAPK5	S1488	D1485G	1485	Missense	distal	-3	no	23.284	13.608	EPSD	ICGC	23.028	Loss
CAMK_MAPKAPK_MK5_MAPKAPK5_ST	O60229	KALRN	Q8IW41	MAPKAPK5	S1488	L1489W	1489	Missense	proximal	1	no	23.284	23.329	EPSD	ICGC;COSMIC	23.028	Up-regulation
CAMK_MAPKAPK_MK5_MAPKAPK5_ST	O60229	KALRN	Q8IW41	MAPKAPK5	S1713	R1712P	1712	Missense	proximal	-1	no	22.878	26.492	EPSD	ICGC;COSMIC	23.028	Gain
CAMK_MAPKAPK_MK5_MAPKAPK5_ST	O60229	KALRN	Q8IW41	MAPKAPK5	S1713	V1715M	1715	Missense	proximal	2	no	22.878	26.402	EPSD	ICGC;COSMIC;GDSC	23.028	Gain
CAMK_MAPKAPK_MK5_MAPKAPK5_ST	P04637	TP53	Q8IW41	MAPKAPK5	S15	E11K	11	Missense	distal	-4	no	28.717	28.592	EPSD	ICGC;COSMIC	23.028	Down-regulation
CAMK_MAPKAPK_MK5_MAPKAPK5_ST	P04637	TP53	Q8IW41	MAPKAPK5	S33	N30I	30	Missense	distal	-3	no	19.092	23.372	EPSD	ICGC	23.028	Gain
CAMK_MAPKAPK_MK5_MAPKAPK5_ST	P04637	TP53	Q8IW41	MAPKAPK5	S37	P34L	34	Missense	distal	-3	no	42.124	37.850	PhosphoSitePlus	ICGC;COSMIC	23.028	Down-regulation
CAMK_MAPKAPK_MK5_MAPKAPK5_ST	P04637	TP53	Q8IW41	MAPKAPK5	S37	S33F	33	Missense	distal	-4	no	42.124	41.645	PhosphoSitePlus	ICGC;COSMIC	23.028	Down-regulation
CAMK_MAPKAPK_MK5_MAPKAPK5_ST	P04637	TP53	Q8IW41	MAPKAPK5	S37	N30I	30	Missense	distal	-7	no	42.124	41.371	PhosphoSitePlus	ICGC	23.028	Down-regulation
CAMK_MAPKAPK_MK5_MAPKAPK5_ST	P04637	TP53	Q8IW41	MAPKAPK5	S46	D48G	48	Missense	proximal	2	no	26.832	27.647	EPSD	ICGC;COSMIC	23.028	Up-regulation
CAMK_MAPKAPK_MK5_MAPKAPK5_ST	P04637	TP53	Q8IW41	MAPKAPK5	S46	Q52K	52	Missense	distal	6	no	26.832	26.731	EPSD	ICGC	23.028	Down-regulation
CAMK_MAPKAPK_MK5_MAPKAPK5_ST	P04637	TP53	Q8IW41	MAPKAPK5	S127	C124R	124	Missense	distal	-3	no	22.875	35.025	EPSD	ICGC;COSMIC;GDSC;CCLE	23.028	Gain
CAMK_MAPKAPK_MK5_MAPKAPK5_ST	P04637	TP53	Q8IW41	MAPKAPK5	S127	T125A	125	Missense	proximal	-2	no	22.875	23.111	EPSD	ICGC;COSMIC	23.028	Gain
CAMK_MAPKAPK_MK5_MAPKAPK5_ST	P04637	TP53	Q8IW41	MAPKAPK5	S127	K120N	120	Missense	distal	-7	no	22.875	23.295	EPSD	ICGC;COSMIC;GDSC;CCLE	23.028	Gain
CAMK_MAPKAPK_MK5_MAPKAPK5_ST	P04637	TP53	Q8IW41	MAPKAPK5	S127	K120M	120	Missense	distal	-7	no	22.875	23.456	EPSD	ICGC;COSMIC	23.028	Gain
CAMK_MAPKAPK_MK5_MAPKAPK5_ST	P04637	TP53	Q8IW41	MAPKAPK5	S183	E180D	180	Missense	distal	-3	no	20.709	25.523	EPSD	ICGC;COSMIC	23.028	Gain
CAMK_MAPKAPK_MK5_MAPKAPK5_ST	P04637	TP53	Q8IW41	MAPKAPK5	S371	T377P	377	Missense	distal	6	no	24.928	24.975	EPSD	ICGC;COSMIC	23.028	Up-regulation
CAMK_MAPKAPK_MK5_MAPKAPK5_ST	P04637	TP53	Q8IW41	MAPKAPK5	S371	G374C	374	Missense	distal	3	no	24.928	25.138	EPSD	ICGC;COSMIC	23.028	Up-regulation
CAMK_MAPKAPK_MK5_MAPKAPK5_ST	P07101	TH	Q8IW41	MAPKAPK5	S19	E20Q	20	Missense	proximal	1	no	38.309	38.332	PhosphoSitePlus;EPSD	ICGC;COSMIC	23.028	Up-regulation
CAMK_MAPKAPK_MK5_MAPKAPK5_ST	P07101	TH	Q8IW41	MAPKAPK5	S19	K12R	12	Missense	distal	-7	no	38.309	38.115	PhosphoSitePlus;EPSD	ICGC;COSMIC	23.028	Down-regulation
CAMK_DAPK_DAPK_DAPK2_ST	Q9UIK4	DAPK2	Q9UIK4	DAPK2	T275	R271W	271	Missense	distal	-4	no	3.511	3.150	EPSD	ICGC	1.958	Down-regulation
CAMK_DAPK_DAPK_DAPK2_ST	Q9UIK4	DAPK2	Q9UIK4	DAPK2	T275	L274I	274	Missense	proximal	-1	no	3.511	3.454	EPSD	ICGC	1.958	Down-regulation
CAMK_DAPK_DAPK_DAPK2_ST	Q9UIK4	DAPK2	Q9UIK4	DAPK2	S318	R313G	313	Missense	distal	-5	no	5.663	4.412	PhosphoSitePlus	ICGC;COSMIC	1.958	Down-regulation
CAMK_DAPK_DAPK_DAPK2_ST	Q9UIK4	DAPK2	Q9UIK4	DAPK2	S320	R313G	313	Missense	distal	-7	no	2.303	2.460	EPSD	ICGC;COSMIC	1.958	Up-regulation
CAMK_DAPK_DAPK_DAPK2_ST	Q8N122	RPTOR	Q9UIK4	DAPK2	T700	T699M	699	Missense	proximal	-1	no	2.705	2.690	EPSD	ICGC;COSMIC	1.958	Down-regulation
CAMK_DAPK_DAPK_DAPK2_ST	Q8N122	RPTOR	Q9UIK4	DAPK2	S854	T853M	853	Missense	proximal	-1	no	2.343	2.328	EPSD	ICGC;COSMIC	1.958	Down-regulation
CAMK_DAPK_DAPK_DAPK2_ST	Q8N122	RPTOR	Q9UIK4	DAPK2	T857	T853M	853	Missense	distal	-4	no	2.033	1.983	EPSD	ICGC;COSMIC	1.958	Down-regulation
AGC_PKC_PKCh_PRKCH_ST	P05107	ITGB2	P24723	PRKCH	T118	R121L	121	Missense	distal	3	no	24.636	25.319	EPSD	ICGC;COSMIC	22.099	Up-regulation
AGC_PKC_PKCh_PRKCH_ST	P05107	ITGB2	P24723	PRKCH	S745	F738C	738	Missense	distal	-7	no	37.899	35.407	PhosphoSitePlus;EPSD	ICGC;COSMIC	22.099	Down-regulation
AGC_PKC_PKCh_PRKCH_ST	P05107	ITGB2	P24723	PRKCH	S745	P752L	752	Missense	distal	7	no	37.899	39.375	PhosphoSitePlus;EPSD	ICGC	22.099	Up-regulation
AGC_PKC_PKCh_PRKCH_ST	P05107	ITGB2	P24723	PRKCH	T758	T758N	758	Missense	central	0	yes	30.507	0.000	EPSD;PhosphoSitePlus	ICGC;COSMIC	22.099	Loss
AGC_PKC_PKCh_PRKCH_ST	P05107	ITGB2	P24723	PRKCH	T758	P752L	752	Missense	distal	-6	no	30.507	28.873	EPSD;PhosphoSitePlus	ICGC	22.099	Down-regulation
AGC_PKC_PKCh_PRKCH_ST	Q06124	PTPN11	P24723	PRKCH	S28	G27S	27	Missense	proximal	-1	no	23.957	24.245	EPSD	ICGC;COSMIC	22.099	Up-regulation
AGC_PKC_PKCh_PRKCH_ST	Q06124	PTPN11	P24723	PRKCH	S28	A31S	31	Missense	distal	3	no	23.957	24.191	EPSD	ICGC	22.099	Up-regulation
AGC_PKC_PKCh_PRKCH_ST	Q06124	PTPN11	P24723	PRKCH	S28	G27C	27	Missense	proximal	-1	no	23.957	23.756	EPSD	ICGC	22.099	Down-regulation
AGC_PKC_PKCh_PRKCH_ST	Q06124	PTPN11	P24723	PRKCH	S140	P144H	144	Missense	distal	4	no	25.170	24.598	EPSD	ICGC;COSMIC	22.099	Down-regulation
AGC_PKC_PKCh_PRKCH_ST	Q06124	PTPN11	P24723	PRKCH	S140	E139D	139	Missense	proximal	-1	no	25.170	24.266	EPSD	ICGC;COSMIC	22.099	Down-regulation
AGC_PKC_PKCh_PRKCH_ST	Q06124	PTPN11	P24723	PRKCH	S160	G158W	158	Missense	proximal	-2	no	23.396	22.953	EPSD	ICGC	22.099	Down-regulation
AGC_PKC_PKCh_PRKCH_ST	Q06124	PTPN11	P24723	PRKCH	S160	D155Y	155	Missense	distal	-5	no	23.396	25.209	EPSD	ICGC;COSMIC	22.099	Up-regulation
AGC_PKC_PKCh_PRKCH_ST	Q06124	PTPN11	P24723	PRKCH	S189	F187Y	187	Missense	proximal	-2	no	20.667	23.678	EPSD	ICGC;COSMIC	22.099	Gain
AGC_PKC_PKCh_PRKCH_ST	P49841	GSK3B	P24723	PRKCH	T7	A11S	11	Missense	distal	4	no	18.296	22.143	EPSD	ICGC;COSMIC	22.099	Gain
AGC_PKC_PKCh_PRKCH_ST	P49841	GSK3B	P24723	PRKCH	T8	A11S	11	Missense	distal	3	no	24.307	24.541	EPSD	ICGC;COSMIC	22.099	Up-regulation
AGC_PKC_PKCh_PRKCH_ST	P49841	GSK3B	P24723	PRKCH	S9	A11S	11	Missense	proximal	2	no	43.547	41.490	PhosphoSitePlus	ICGC;COSMIC	22.099	Down-regulation
AGC_PKC_PKCh_PRKCH_ST	P49841	GSK3B	P24723	PRKCH	S29	D33E	33	Missense	distal	4	no	21.727	22.699	EPSD	ICGC	22.099	Gain
AGC_PKC_PKCh_PRKCH_ST	P49841	GSK3B	P24723	PRKCH	S55	D49E	49	Missense	distal	-6	no	23.298	27.405	EPSD	ICGC	22.099	Up-regulation
AGC_PKC_PKCh_PRKCH_ST	P49841	GSK3B	P24723	PRKCH	S55	Q52K	52	Missense	distal	-3	no	23.298	23.351	EPSD	ICGC	22.099	Up-regulation
AGC_PKC_PKCh_PRKCH_ST	P49841	GSK3B	P24723	PRKCH	S55	E53K	53	Missense	proximal	-2	no	23.298	20.189	EPSD	ICGC;COSMIC	22.099	Loss
AGC_PKC_PKCh_PRKCH_ST	P49841	GSK3B	P24723	PRKCH	S215	S219Y	219	Missense	distal	4	no	24.060	23.332	EPSD	ICGC;COSMIC	22.099	Down-regulation
AGC_PKC_PKCh_PRKCH_ST	P49841	GSK3B	P24723	PRKCH	S215	P212T	212	Missense	distal	-3	no	24.060	23.971	EPSD	ICGC	22.099	Down-regulation
AGC_PKC_PKCh_PRKCH_ST	P49841	GSK3B	P24723	PRKCH	T275	L273R	273	Missense	proximal	-2	no	18.927	25.321	EPSD	ICGC	22.099	Gain
AGC_PKC_PKCh_PRKCH_ST	P49841	GSK3B	P24723	PRKCH	T395	S389P	389	Missense	distal	-6	no	20.676	24.358	EPSD	ICGC;COSMIC	22.099	Gain
AGC_PKC_PKCh_PRKCH_ST	P24723	PRKCH	P24723	PRKCH	S28	R30L	30	Missense	proximal	2	no	40.511	39.344	PhosphoSitePlus;EPSD	ICGC	22.099	Down-regulation
AGC_PKC_PKCh_PRKCH_ST	P24723	PRKCH	P24723	PRKCH	S28	L29M	29	Missense	proximal	1	no	40.511	34.012	PhosphoSitePlus;EPSD	ICGC;COSMIC	22.099	Down-regulation
AGC_PKC_PKCh_PRKCH_ST	P24723	PRKCH	P24723	PRKCH	S32	R30L	30	Missense	proximal	-2	no	42.756	36.362	EPSD;PhosphoSitePlus	ICGC	22.099	Down-regulation
AGC_PKC_PKCh_PRKCH_ST	P24723	PRKCH	P24723	PRKCH	S32	Q39L	39	Missense	distal	7	no	42.756	43.689	EPSD;PhosphoSitePlus	ICGC;COSMIC	22.099	Up-regulation
AGC_PKC_PKCh_PRKCH_ST	P24723	PRKCH	P24723	PRKCH	S32	L29M	29	Missense	distal	-3	no	42.756	42.812	EPSD;PhosphoSitePlus	ICGC;COSMIC	22.099	Up-regulation
AGC_PKC_PKCh_PRKCH_ST	P24723	PRKCH	P24723	PRKCH	T513	C506F	506	Missense	distal	-7	no	23.664	26.155	EPSD	ICGC	22.099	Up-regulation
AGC_PKC_PKCh_PRKCH_ST	P24723	PRKCH	P24723	PRKCH	T513	F514L	514	Missense	proximal	1	no	23.664	20.182	EPSD	ICGC	22.099	Loss
AGC_PKC_PKCh_PRKCH_ST	Q15139	PRKD1	P24723	PRKCH	S223	R216H	216	Missense	distal	-7	no	23.139	23.897	EPSD	ICGC	22.099	Up-regulation
AGC_PKC_PKCh_PRKCH_ST	Q15139	PRKD1	P24723	PRKCH	S379	D386E	386	Missense	distal	7	no	23.225	18.883	EPSD	ICGC	22.099	Loss
AGC_PKC_PKCh_PRKCH_ST	Q15139	PRKD1	P24723	PRKCH	S379	D386N	386	Missense	distal	7	no	23.225	21.885	EPSD	ICGC;COSMIC	22.099	Loss
AGC_PKC_PKCh_PRKCH_ST	Q15139	PRKD1	P24723	PRKCH	T422	R418K	418	Missense	distal	-4	no	23.621	24.216	EPSD	ICGC;COSMIC	22.099	Up-regulation
AGC_PKC_PKCh_PRKCH_ST	Q15139	PRKD1	P24723	PRKCH	T422	M424T	424	Missense	proximal	2	no	23.621	24.630	EPSD	ICGC;COSMIC	22.099	Up-regulation
AGC_PKC_PKCh_PRKCH_ST	Q15139	PRKD1	P24723	PRKCH	S738	R740W	740	Missense	proximal	2	no	42.688	41.065	PhosphoSitePlus;EPSD	ICGC;COSMIC;GDSC;CCLE	22.099	Down-regulation
AGC_PKC_PKCh_PRKCH_ST	Q15139	PRKD1	P24723	PRKCH	S738	R740L	740	Missense	proximal	2	no	42.688	41.521	PhosphoSitePlus;EPSD	ICGC;COSMIC	22.099	Down-regulation
AGC_PKC_PKCh_PRKCH_ST	Q15139	PRKD1	P24723	PRKCH	S742	R740W	740	Missense	proximal	-2	no	43.278	37.049	EPSD;PhosphoSitePlus	ICGC;COSMIC;GDSC;CCLE	22.099	Down-regulation
AGC_PKC_PKCh_PRKCH_ST	Q15139	PRKD1	P24723	PRKCH	S742	R740L	740	Missense	proximal	-2	no	43.278	36.884	EPSD;PhosphoSitePlus	ICGC;COSMIC	22.099	Down-regulation
AGC_PKC_PKCh_PRKCH_ST	Q9BZL6	PRKD2	P24723	PRKCH	T276	T276K	276	Missense	central	0	yes	22.532	0.000	EPSD	ICGC	22.099	Loss
AGC_PKC_PKCh_PRKCH_ST	Q9BZL6	PRKD2	P24723	PRKCH	S529	A528E	528	Missense	proximal	-1	no	24.008	24.506	EPSD	ICGC	22.099	Up-regulation
AGC_PKC_PKCh_PRKCH_ST	P09211	GSTP1	P24723	PRKCH	T5	P10Q	10	Missense	distal	5	no	23.409	22.332	EPSD	ICGC;COSMIC	22.099	Down-regulation
AGC_PKC_PKCh_PRKCH_ST	P09211	GSTP1	P24723	PRKCH	T5	R12L	12	Missense	distal	7	no	23.409	24.733	EPSD	ICGC;COSMIC	22.099	Up-regulation
AGC_PKC_PKCh_PRKCH_ST	P09211	GSTP1	P24723	PRKCH	S43	S43A	43	Missense	central	0	yes	41.730	0.000	EPSD;PhosphoSitePlus	ICGC;COSMIC	22.099	Loss
AGC_PKC_PKCh_PRKCH_ST	P09211	GSTP1	P24723	PRKCH	S185	A179S	179	Missense	distal	-6	no	39.461	37.020	PhosphoSitePlus;EPSD	ICGC;COSMIC	22.099	Down-regulation
AGC_PKC_PKCh_PRKCH_ST	P09211	GSTP1	P24723	PRKCH	S185	G182W	182	Missense	distal	-3	no	39.461	39.544	PhosphoSitePlus;EPSD	ICGC;COSMIC	22.099	Up-regulation
AGC_PKC_PKCh_PRKCH_ST	P49840	GSK3A	P24723	PRKCH	S52	G45D	45	Missense	distal	-7	no	25.404	24.442	EPSD	ICGC	22.099	Down-regulation
AGC_PKC_PKCh_PRKCH_ST	P49840	GSK3A	P24723	PRKCH	S97	D96E	96	Missense	proximal	-1	no	24.257	25.161	EPSD	ICGC;COSMIC	22.099	Up-regulation
AGC_PKC_PKCh_PRKCH_ST	P49840	GSK3A	P24723	PRKCH	S97	R95G	95	Missense	proximal	-2	no	24.257	18.471	EPSD	ICGC;COSMIC	22.099	Loss
AGC_PKC_PKCh_PRKCH_ST	P49840	GSK3A	P24723	PRKCH	S97	G98R	98	Missense	proximal	1	no	24.257	21.782	EPSD	ICGC	22.099	Loss
AGC_PKC_PKCh_PRKCH_ST	P49840	GSK3A	P24723	PRKCH	S97	V103A	103	Missense	distal	6	no	24.257	23.498	EPSD	ICGC;COSMIC	22.099	Down-regulation
AGC_PKC_PKCh_PRKCH_ST	P49840	GSK3A	P24723	PRKCH	S129	V133M	133	Missense	distal	4	no	21.849	25.875	EPSD	ICGC;COSMIC;GDSC;CCLE	22.099	Gain
AGC_PKC_PKCh_PRKCH_ST	P49840	GSK3A	P24723	PRKCH	S129	G131E	131	Missense	proximal	2	no	21.849	22.531	EPSD	ICGC	22.099	Gain
AGC_PKC_PKCh_PRKCH_ST	P49840	GSK3A	P24723	PRKCH	S401	H400Q	400	Missense	proximal	-1	no	24.798	24.725	EPSD	ICGC;COSMIC	22.099	Down-regulation
Other_PLK_PLK1_PLK1_ST	Q14203	DCTN1	P53350	PLK1	S23	P26F	26	Missense	distal	3	no	11.515	11.554	EPSD	ICGC	10.919	Up-regulation
Other_PLK_PLK1_PLK1_ST	Q14203	DCTN1	P53350	PLK1	S23	R25Q	25	Missense	proximal	2	no	11.515	11.840	EPSD	ICGC;COSMIC	10.919	Up-regulation
Other_PLK_PLK1_PLK1_ST	Q14203	DCTN1	P53350	PLK1	S111	K115E	115	Missense	distal	4	no	11.527	11.900	EPSD	ICGC	10.919	Up-regulation
Other_PLK_PLK1_PLK1_ST	Q14203	DCTN1	P53350	PLK1	S111	S111Y	111	Missense	central	0	yes	11.527	0.000	EPSD	ICGC	10.919	Loss
Other_PLK_PLK1_PLK1_ST	Q14203	DCTN1	P53350	PLK1	T158	A156D	156	Missense	proximal	-2	no	9.873	12.444	EPSD	ICGC;COSMIC	10.919	Gain
Other_PLK_PLK1_PLK1_ST	Q14203	DCTN1	P53350	PLK1	S179	P186Q	186	Missense	distal	7	no	14.194	14.198	PhosphoSitePlus	ICGC	10.919	Up-regulation
Other_PLK_PLK1_PLK1_ST	Q14203	DCTN1	P53350	PLK1	S179	P183S	183	Missense	distal	4	no	14.194	14.516	PhosphoSitePlus	ICGC;COSMIC	10.919	Up-regulation
Other_PLK_PLK1_PLK1_ST	Q14203	DCTN1	P53350	PLK1	S541	A540T	540	Missense	proximal	-1	no	11.150	10.870	EPSD	ICGC;COSMIC	10.919	Loss
Other_PLK_PLK1_PLK1_ST	Q14203	DCTN1	P53350	PLK1	T1158	S1153I	1153	Missense	distal	-5	no	11.016	11.384	EPSD	ICGC;COSMIC	10.919	Up-regulation
Other_PLK_PLK1_PLK1_ST	O60563	CCNT1	P53350	PLK1	S22	S24Y	24	Missense	proximal	2	no	12.291	11.924	EPSD	ICGC	10.919	Down-regulation
Other_PLK_PLK1_PLK1_ST	O60563	CCNT1	P53350	PLK1	S22	P23Q	23	Missense	proximal	1	no	12.291	11.984	EPSD	ICGC	10.919	Down-regulation
Other_PLK_PLK1_PLK1_ST	O60563	CCNT1	P53350	PLK1	T278	Q281K	281	Missense	distal	3	no	11.485	11.387	EPSD	ICGC	10.919	Down-regulation
Other_PLK_PLK1_PLK1_ST	O60563	CCNT1	P53350	PLK1	T278	T282K	282	Missense	distal	4	no	11.485	11.293	EPSD	ICGC	10.919	Down-regulation
Other_PLK_PLK1_PLK1_ST	O60563	CCNT1	P53350	PLK1	T278	T274K	274	Missense	distal	-4	no	11.485	11.455	EPSD	ICGC	10.919	Down-regulation
Other_PLK_PLK1_PLK1_ST	O60563	CCNT1	P53350	PLK1	T282	I287V	287	Missense	distal	5	no	11.337	10.868	EPSD	ICGC;COSMIC	10.919	Loss
Other_PLK_PLK1_PLK1_ST	O60563	CCNT1	P53350	PLK1	T282	Q281K	281	Missense	proximal	-1	no	11.337	11.095	EPSD	ICGC	10.919	Down-regulation
Other_PLK_PLK1_PLK1_ST	O60563	CCNT1	P53350	PLK1	T282	T282K	282	Missense	central	0	yes	11.337	0.000	EPSD	ICGC	10.919	Loss
Other_PLK_PLK1_PLK1_ST	O60563	CCNT1	P53350	PLK1	S499	T501S	501	Missense	proximal	2	no	12.128	12.769	EPSD	ICGC;COSMIC	10.919	Up-regulation
Other_PLK_PLK1_PLK1_ST	O60563	CCNT1	P53350	PLK1	S499	V496I	496	Missense	distal	-3	no	12.128	12.404	EPSD	ICGC;COSMIC	10.919	Up-regulation
Other_PLK_PLK1_PLK1_ST	O60563	CCNT1	P53350	PLK1	S560	S566F	566	Missense	distal	6	no	12.630	12.054	EPSD	ICGC	10.919	Down-regulation
Other_PLK_PLK1_PLK1_ST	O60563	CCNT1	P53350	PLK1	S564	S566F	566	Missense	proximal	2	no	13.753	13.202	PhosphoSitePlus	ICGC	10.919	Down-regulation
Other_PLK_PLK1_PLK1_ST	O60563	CCNT1	P53350	PLK1	S577	A583D	583	Missense	distal	6	no	11.112	11.100	EPSD	ICGC	10.919	Down-regulation
Other_PLK_PLK1_PLK1_ST	O60563	CCNT1	P53350	PLK1	S577	G575V	575	Missense	proximal	-2	no	11.112	11.821	EPSD	ICGC;COSMIC	10.919	Up-regulation
Other_PLK_PLK1_PLK1_ST	O60563	CCNT1	P53350	PLK1	S577	R572H	572	Missense	distal	-5	no	11.112	10.309	EPSD	ICGC;COSMIC;GDSC	10.919	Loss
Other_PLK_PLK1_PLK1_ST	O60563	CCNT1	P53350	PLK1	T580	A583D	583	Missense	distal	3	no	11.250	11.672	EPSD	ICGC	10.919	Up-regulation
Other_PLK_PLK1_PLK1_ST	O60563	CCNT1	P53350	PLK1	T580	G575V	575	Missense	distal	-5	no	11.250	11.063	EPSD	ICGC;COSMIC	10.919	Down-regulation
Other_PLK_PLK1_PLK1_ST	Q9Y2I6	NINL	P53350	PLK1	S87	R81S	81	Missense	distal	-6	no	14.014	14.462	EPSD;PhosphoSitePlus	ICGC	10.919	Up-regulation
Other_PLK_PLK1_PLK1_ST	Q9Y2I6	NINL	P53350	PLK1	S87	D84N	84	Missense	distal	-3	no	14.014	13.914	EPSD;PhosphoSitePlus	ICGC;COSMIC	10.919	Down-regulation
Other_PLK_PLK1_PLK1_ST	Q9Y2I6	NINL	P53350	PLK1	S87	R81C	81	Missense	distal	-6	no	14.014	13.259	EPSD;PhosphoSitePlus	ICGC;COSMIC	10.919	Down-regulation
Other_PLK_PLK1_PLK1_ST	Q9Y2I6	NINL	P53350	PLK1	S88	R81S	81	Missense	distal	-7	no	12.809	13.306	PhosphoSitePlus;EPSD	ICGC	10.919	Up-regulation
Other_PLK_PLK1_PLK1_ST	Q9Y2I6	NINL	P53350	PLK1	S88	D84N	84	Missense	distal	-4	no	12.809	12.868	PhosphoSitePlus;EPSD	ICGC;COSMIC	10.919	Up-regulation
Other_PLK_PLK1_PLK1_ST	Q9Y2I6	NINL	P53350	PLK1	S88	R81C	81	Missense	distal	-7	no	12.809	12.688	PhosphoSitePlus;EPSD	ICGC;COSMIC	10.919	Down-regulation
Other_PLK_PLK1_PLK1_ST	Q9Y2I6	NINL	P53350	PLK1	S448	R444W	444	Missense	distal	-4	no	11.419	11.834	EPSD	ICGC;COSMIC	10.919	Up-regulation
Other_PLK_PLK1_PLK1_ST	Q9Y2I6	NINL	P53350	PLK1	S585	R578W	578	Missense	distal	-7	no	10.512	11.098	EPSD	ICGC;COSMIC	10.919	Gain
Other_PLK_PLK1_PLK1_ST	Q9Y2I6	NINL	P53350	PLK1	S585	P586L	586	Missense	proximal	1	no	10.512	11.358	EPSD	ICGC	10.919	Gain
Other_PLK_PLK1_PLK1_ST	Q9Y2I6	NINL	P53350	PLK1	S606	P602T	602	Missense	distal	-4	no	12.804	12.563	EPSD	ICGC	10.919	Down-regulation
Other_PLK_PLK1_PLK1_ST	Q9Y2I6	NINL	P53350	PLK1	S606	S606L	606	Missense	central	0	yes	12.804	0.000	EPSD	ICGC	10.919	Loss
Other_PLK_PLK1_PLK1_ST	Q9Y2I6	NINL	P53350	PLK1	S606	A603S	603	Missense	distal	-3	no	12.804	12.281	EPSD	ICGC;COSMIC	10.919	Down-regulation
Other_PLK_PLK1_PLK1_ST	Q9Y2I6	NINL	P53350	PLK1	S606	G604C	604	Missense	proximal	-2	no	12.804	11.074	EPSD	ICGC;COSMIC	10.919	Down-regulation
Other_PLK_PLK1_PLK1_ST	Q9Y2I6	NINL	P53350	PLK1	S686	E681D	681	Missense	distal	-5	no	12.596	12.938	EPSD;PhosphoSitePlus	ICGC;COSMIC	10.919	Up-regulation
Other_PLK_PLK1_PLK1_ST	Q9Y2I6	NINL	P53350	PLK1	T758	R754S	754	Missense	distal	-4	no	10.692	11.259	EPSD	ICGC;COSMIC	10.919	Gain
Other_PLK_PLK1_PLK1_ST	Q9Y2I6	NINL	P53350	PLK1	T1094	H1087R	1087	Missense	distal	-7	no	11.828	11.449	EPSD	ICGC;COSMIC	10.919	Down-regulation
Other_PLK_PLK1_PLK1_ST	Q9Y2I6	NINL	P53350	PLK1	S1267	S1267G	1267	Missense	central	0	yes	13.812	0.000	EPSD	ICGC;COSMIC	10.919	Loss
Other_PLK_PLK1_PLK1_ST	Q9Y2I6	NINL	P53350	PLK1	S1267	A1273D	1273	Missense	distal	6	no	13.812	13.800	EPSD	ICGC	10.919	Down-regulation
Other_PLK_PLK1_PLK1_ST	P60484	PTEN	P53350	PLK1	S338	L345Q	345	Missense	distal	7	no	10.952	10.985	EPSD	ICGC;COSMIC	10.919	Up-regulation
Other_PLK_PLK1_PLK1_ST	P60484	PTEN	P53350	PLK1	S338	L345M	345	Missense	distal	7	no	10.952	11.022	EPSD	ICGC;COSMIC	10.919	Up-regulation
Other_PLK_PLK1_PLK1_ST	P60484	PTEN	P53350	PLK1	S338	L345P	345	Missense	distal	7	no	10.952	10.981	EPSD	ICGC;COSMIC	10.919	Up-regulation
Other_PLK_PLK1_PLK1_ST	P60484	PTEN	P53350	PLK1	S338	D331N	331	Missense	distal	-7	no	10.952	11.092	EPSD	ICGC;COSMIC	10.919	Up-regulation
Other_PLK_PLK1_PLK1_ST	P60484	PTEN	P53350	PLK1	S338	R335G	335	Missense	distal	-3	no	10.952	10.893	EPSD	ICGC;COSMIC	10.919	Loss
Other_PLK_PLK1_PLK1_ST	P60484	PTEN	P53350	PLK1	S362	S360R	360	Missense	proximal	-2	no	11.719	11.494	EPSD	ICGC	10.919	Down-regulation
Other_PLK_PLK1_PLK1_ST	P60484	PTEN	P53350	PLK1	T382	E388Q	388	Missense	distal	6	no	12.112	11.972	EPSD;PhosphoSitePlus	ICGC;COSMIC	10.919	Down-regulation
Other_PLK_PLK1_PLK1_ST	P60484	PTEN	P53350	PLK1	T383	E388Q	388	Missense	distal	5	no	14.176	14.017	EPSD;PhosphoSitePlus	ICGC;COSMIC	10.919	Down-regulation
Other_PLK_PLK1_PLK1_ST	P30305	CDC25B	P53350	PLK1	S50	R45W	45	Missense	distal	-5	no	13.331	13.099	EPSD;PhosphoSitePlus	ICGC;COSMIC	10.919	Down-regulation
Other_PLK_PLK1_PLK1_ST	P30305	CDC25B	P53350	PLK1	T127	E129D	129	Missense	proximal	2	no	13.080	13.671	PhosphoSitePlus;EPSD	ICGC	10.919	Up-regulation
Other_PLK_PLK1_PLK1_ST	P30305	CDC25B	P53350	PLK1	T127	D120Y	120	Missense	distal	-7	no	13.080	12.818	PhosphoSitePlus;EPSD	ICGC	10.919	Down-regulation
Other_PLK_PLK1_PLK1_ST	P30305	CDC25B	P53350	PLK1	T167	Q170H	170	Missense	distal	3	no	12.471	12.407	EPSD;PhosphoSitePlus	ICGC;COSMIC	10.919	Down-regulation
Other_PLK_PLK1_PLK1_ST	P30305	CDC25B	P53350	PLK1	S387	E382G	382	Missense	distal	-5	no	10.550	11.046	EPSD	ICGC;COSMIC	10.919	Gain
Other_PLK_PLK1_PLK1_ST	P30305	CDC25B	P53350	PLK1	S397	A399T	399	Missense	proximal	2	no	13.968	13.567	EPSD;PhosphoSitePlus	ICGC;COSMIC	10.919	Down-regulation
Other_PLK_PLK1_PLK1_ST	P30305	CDC25B	P53350	PLK1	S397	A399G	399	Missense	proximal	2	no	13.968	12.628	EPSD;PhosphoSitePlus	ICGC;COSMIC	10.919	Down-regulation
Other_PLK_PLK1_PLK1_ST	P30305	CDC25B	P53350	PLK1	T419	L424F	424	Missense	distal	5	no	10.570	11.011	EPSD	ICGC;COSMIC	10.919	Gain
Other_PLK_PLK1_PLK1_ST	P30305	CDC25B	P53350	PLK1	S465	E464Q	464	Missense	proximal	-1	no	12.264	11.935	EPSD;PhosphoSitePlus	ICGC;COSMIC	10.919	Down-regulation
Other_PLK_PLK1_PLK1_ST	P30305	CDC25B	P53350	PLK1	S470	E464Q	464	Missense	distal	-6	no	11.498	11.379	EPSD	ICGC;COSMIC	10.919	Down-regulation
Other_PLK_PLK1_PLK1_ST	P30305	CDC25B	P53350	PLK1	S563	S563C	563	Missense	central	0	yes	11.189	0.000	EPSD	ICGC;COSMIC	10.919	Loss
Other_PLK_PLK1_PLK1_ST	P30305	CDC25B	P53350	PLK1	S563	W564L	564	Missense	proximal	1	no	11.189	11.617	EPSD	ICGC;COSMIC	10.919	Up-regulation
Other_PLK_PLK1_PLK1_ST	P33981	TTK	P53350	PLK1	S49	V52F	52	Missense	distal	3	no	11.653	11.561	EPSD	ICGC;COSMIC	10.919	Down-regulation
Other_PLK_PLK1_PLK1_ST	P33981	TTK	P53350	PLK1	S49	S49A	49	Missense	central	0	yes	11.653	0.000	EPSD	ICGC;COSMIC	10.919	Loss
Other_PLK_PLK1_PLK1_ST	P33981	TTK	P53350	PLK1	S291	P294H	294	Missense	distal	3	no	14.312	14.298	EPSD;PhosphoSitePlus	ICGC;COSMIC	10.919	Down-regulation
Other_PLK_PLK1_PLK1_ST	P33981	TTK	P53350	PLK1	S353	I354V	354	Missense	proximal	1	no	11.291	11.099	EPSD	ICGC;COSMIC	10.919	Down-regulation
Other_PLK_PLK1_PLK1_ST	P33981	TTK	P53350	PLK1	S404	P400H	400	Missense	distal	-4	no	12.414	12.270	EPSD	ICGC;COSMIC	10.919	Down-regulation
Other_PLK_PLK1_PLK1_ST	P33981	TTK	P53350	PLK1	T831	G838S	838	Missense	distal	7	no	12.235	12.236	EPSD	ICGC;COSMIC	10.919	Up-regulation
Other_PLK_PLK1_PLK1_ST	P33981	TTK	P53350	PLK1	S845	G838S	838	Missense	distal	-7	no	13.316	14.012	EPSD	ICGC;COSMIC	10.919	Up-regulation
Other_PLK_PLK1_PLK1_ST	Q96BK5	PINX1	P53350	PLK1	S110	K106N	106	Missense	distal	-4	no	12.373	12.631	EPSD;PhosphoSitePlus	ICGC;COSMIC	10.919	Up-regulation
Other_PLK_PLK1_PLK1_ST	Q96BK5	PINX1	P53350	PLK1	S110	S110G	110	Missense	central	0	yes	12.373	0.000	EPSD;PhosphoSitePlus	ICGC	10.919	Loss
Other_PLK_PLK1_PLK1_ST	Q96BK5	PINX1	P53350	PLK1	S117	S110G	110	Missense	distal	-7	no	12.300	11.603	EPSD;PhosphoSitePlus	ICGC	10.919	Down-regulation
Other_PLK_PLK1_PLK1_ST	Q96BK5	PINX1	P53350	PLK1	S161	T155N	155	Missense	distal	-6	no	14.209	14.115	EPSD	ICGC	10.919	Down-regulation
Other_PLK_PLK1_PLK1_ST	Q96BK5	PINX1	P53350	PLK1	S226	T220A	220	Missense	distal	-6	no	11.711	11.779	PhosphoSitePlus;EPSD	ICGC;COSMIC	10.919	Up-regulation
Other_PLK_PLK1_PLK1_ST	Q9H1A4	ANAPC1	P53350	PLK1	S212	M210V	210	Missense	proximal	-2	no	11.649	12.145	EPSD	ICGC;COSMIC	10.919	Up-regulation
Other_PLK_PLK1_PLK1_ST	Q9H1A4	ANAPC1	P53350	PLK1	S298	T302A	302	Missense	distal	4	no	11.651	11.645	EPSD	ICGC;COSMIC	10.919	Down-regulation
Other_PLK_PLK1_PLK1_ST	Q9H1A4	ANAPC1	P53350	PLK1	S323	S327N	327	Missense	distal	4	no	12.107	11.871	EPSD	ICGC;COSMIC	10.919	Down-regulation
Other_PLK_PLK1_PLK1_ST	Q9H1A4	ANAPC1	P53350	PLK1	S339	R340S	340	Missense	proximal	1	no	10.163	11.327	EPSD	ICGC;COSMIC	10.919	Gain
Other_PLK_PLK1_PLK1_ST	Q9H1A4	ANAPC1	P53350	PLK1	S377	P378S	378	Missense	proximal	1	no	13.023	11.901	EPSD;PhosphoSitePlus	ICGC	10.919	Down-regulation
Other_PLK_PLK1_PLK1_ST	Q9H1A4	ANAPC1	P53350	PLK1	S386	P387Q	387	Missense	proximal	1	no	11.140	10.833	EPSD	ICGC;COSMIC	10.919	Loss
Other_PLK_PLK1_PLK1_ST	Q9H1A4	ANAPC1	P53350	PLK1	T520	P517T	517	Missense	distal	-3	no	10.514	11.308	PhosphoSitePlus;EPSD	ICGC;COSMIC	10.919	Gain
Other_PLK_PLK1_PLK1_ST	Q9H1A4	ANAPC1	P53350	PLK1	T524	P517T	517	Missense	distal	-7	no	11.557	11.759	EPSD	ICGC;COSMIC	10.919	Up-regulation
Other_PLK_PLK1_PLK1_ST	Q9H1A4	ANAPC1	P53350	PLK1	T524	R527Q	527	Missense	distal	3	no	11.557	11.753	EPSD	ICGC;COSMIC	10.919	Up-regulation
Other_PLK_PLK1_PLK1_ST	Q9H1A4	ANAPC1	P53350	PLK1	T530	R527Q	527	Missense	distal	-3	no	12.042	11.367	EPSD;PhosphoSitePlus	ICGC;COSMIC	10.919	Down-regulation
Other_PLK_PLK1_PLK1_ST	Q9H1A4	ANAPC1	P53350	PLK1	S1058	F1062L	1062	Missense	distal	4	no	11.200	11.401	EPSD	ICGC;COSMIC	10.919	Up-regulation
Other_PLK_PLK1_PLK1_ST	Q99661	KIF2C	P53350	PLK1	T33	L36F	36	Missense	distal	3	no	10.995	11.202	EPSD	ICGC	10.919	Up-regulation
Other_PLK_PLK1_PLK1_ST	Q99661	KIF2C	P53350	PLK1	S519	A522T	522	Missense	distal	3	no	12.443	12.482	EPSD	ICGC	10.919	Up-regulation
Other_PLK_PLK1_PLK1_ST	Q99661	KIF2C	P53350	PLK1	S519	A522V	522	Missense	distal	3	no	12.443	12.770	EPSD	ICGC	10.919	Up-regulation
Other_PLK_PLK1_PLK1_ST	Q99661	KIF2C	P53350	PLK1	S519	A522S	522	Missense	distal	3	no	12.443	12.619	EPSD	ICGC	10.919	Up-regulation
Other_PLK_PLK1_PLK1_ST	Q99661	KIF2C	P53350	PLK1	S519	G513A	513	Missense	distal	-6	no	12.443	12.953	EPSD	ICGC	10.919	Up-regulation
Other_PLK_PLK1_PLK1_ST	Q99661	KIF2C	P53350	PLK1	S621	E623Q	623	Missense	proximal	2	no	11.674	11.863	EPSD;PhosphoSitePlus	ICGC	10.919	Up-regulation
Other_PLK_PLK1_PLK1_ST	Q99661	KIF2C	P53350	PLK1	S633	E636G	636	Missense	distal	3	no	13.762	13.585	PhosphoSitePlus;EPSD	ICGC	10.919	Down-regulation
Other_PLK_PLK1_PLK1_ST	Q99661	KIF2C	P53350	PLK1	S633	E636D	636	Missense	distal	3	no	13.762	13.828	PhosphoSitePlus;EPSD	ICGC	10.919	Up-regulation
Other_PLK_PLK1_PLK1_ST	Q99661	KIF2C	P53350	PLK1	T639	E636G	636	Missense	distal	-3	no	11.385	12.327	EPSD	ICGC	10.919	Up-regulation
Other_PLK_PLK1_PLK1_ST	Q99661	KIF2C	P53350	PLK1	T639	E643K	643	Missense	distal	4	no	11.385	11.011	EPSD	ICGC	10.919	Down-regulation
Other_PLK_PLK1_PLK1_ST	Q99661	KIF2C	P53350	PLK1	T639	E636D	636	Missense	distal	-3	no	11.385	11.844	EPSD	ICGC	10.919	Up-regulation
Other_PLK_PLK1_PLK1_ST	P35568	IRS1	P53350	PLK1	S99	F93L	93	Missense	distal	-6	no	11.482	11.665	EPSD	ICGC;COSMIC	10.919	Up-regulation
Other_PLK_PLK1_PLK1_ST	P35568	IRS1	P53350	PLK1	S99	A96S	96	Missense	distal	-3	no	11.482	10.959	EPSD	ICGC	10.919	Down-regulation
Other_PLK_PLK1_PLK1_ST	P35568	IRS1	P53350	PLK1	S99	A101S	101	Missense	proximal	2	no	11.482	11.721	EPSD	ICGC;COSMIC	10.919	Up-regulation
Other_PLK_PLK1_PLK1_ST	P35568	IRS1	P53350	PLK1	S330	G332S	332	Missense	proximal	2	no	10.743	12.323	EPSD	ICGC;COSMIC	10.919	Gain
Other_PLK_PLK1_PLK1_ST	P35568	IRS1	P53350	PLK1	S345	S345N	345	Missense	central	0	yes	12.466	0.000	EPSD	ICGC	10.919	Loss
Other_PLK_PLK1_PLK1_ST	P35568	IRS1	P53350	PLK1	S372	L369H	369	Missense	distal	-3	no	14.136	13.522	EPSD	ICGC;COSMIC	10.919	Down-regulation
Other_PLK_PLK1_PLK1_ST	P35568	IRS1	P53350	PLK1	S396	P389T	389	Missense	distal	-7	no	10.775	10.977	EPSD	ICGC	10.919	Gain
Other_PLK_PLK1_PLK1_ST	P35568	IRS1	P53350	PLK1	S396	S393T	393	Missense	distal	-3	no	10.775	11.152	EPSD	ICGC;COSMIC	10.919	Gain
Other_PLK_PLK1_PLK1_ST	P35568	IRS1	P53350	PLK1	S398	S402C	402	Missense	distal	4	no	11.301	10.774	EPSD	ICGC;COSMIC	10.919	Loss
Other_PLK_PLK1_PLK1_ST	P35568	IRS1	P53350	PLK1	S398	S393T	393	Missense	distal	-5	no	11.301	11.516	EPSD	ICGC;COSMIC	10.919	Up-regulation
Other_PLK_PLK1_PLK1_ST	P35568	IRS1	P53350	PLK1	S398	S396G	396	Missense	proximal	-2	no	11.301	10.631	EPSD	ICGC;CCLE	10.919	Loss
Other_PLK_PLK1_PLK1_ST	P35568	IRS1	P53350	PLK1	S415	S412P	412	Missense	distal	-3	no	11.677	11.259	EPSD	ICGC	10.919	Down-regulation
Other_PLK_PLK1_PLK1_ST	P35568	IRS1	P53350	PLK1	S415	S421R	421	Missense	distal	6	no	11.677	11.370	EPSD	ICGC	10.919	Down-regulation
Other_PLK_PLK1_PLK1_ST	P35568	IRS1	P53350	PLK1	S415	A414D	414	Missense	proximal	-1	no	11.677	12.937	EPSD	ICGC	10.919	Up-regulation
Other_PLK_PLK1_PLK1_ST	P35568	IRS1	P53350	PLK1	S415	R411L	411	Missense	distal	-4	no	11.677	12.050	EPSD	ICGC;COSMIC	10.919	Up-regulation
Other_PLK_PLK1_PLK1_ST	P35568	IRS1	P53350	PLK1	S415	R410W	410	Missense	distal	-5	no	11.677	11.445	EPSD	ICGC	10.919	Down-regulation
Other_PLK_PLK1_PLK1_ST	P35568	IRS1	P53350	PLK1	S449	A456D	456	Missense	distal	7	no	11.095	11.043	EPSD	ICGC;COSMIC	10.919	Down-regulation
Other_PLK_PLK1_PLK1_ST	P35568	IRS1	P53350	PLK1	S463	R457H	457	Missense	distal	-6	no	10.684	11.143	EPSD	ICGC;COSMIC	10.919	Gain
Other_PLK_PLK1_PLK1_ST	P35568	IRS1	P53350	PLK1	T552	A557D	557	Missense	distal	5	no	11.154	10.737	EPSD	ICGC	10.919	Loss
Other_PLK_PLK1_PLK1_ST	P35568	IRS1	P53350	PLK1	T605	R600H	600	Missense	distal	-5	no	11.317	10.514	EPSD	ICGC;COSMIC	10.919	Loss
Other_PLK_PLK1_PLK1_ST	P35568	IRS1	P53350	PLK1	S741	P746T	746	Missense	distal	5	no	11.207	10.214	EPSD	ICGC	10.919	Loss
Other_PLK_PLK1_PLK1_ST	P35568	IRS1	P53350	PLK1	S741	P746S	746	Missense	distal	5	no	11.207	10.819	EPSD	ICGC	10.919	Loss
Other_PLK_PLK1_PLK1_ST	P35568	IRS1	P53350	PLK1	S741	D748N	748	Missense	distal	7	no	11.207	11.288	EPSD	ICGC	10.919	Up-regulation
Other_PLK_PLK1_PLK1_ST	P35568	IRS1	P53350	PLK1	S869	R873P	873	Missense	distal	4	no	10.767	11.390	EPSD	ICGC	10.919	Gain
Other_PLK_PLK1_PLK1_ST	P35568	IRS1	P53350	PLK1	S869	P866T	866	Missense	distal	-3	no	10.767	11.561	EPSD	ICGC	10.919	Gain
Other_PLK_PLK1_PLK1_ST	P35568	IRS1	P53350	PLK1	S1038	P1044T	1044	Missense	distal	6	no	10.994	11.126	EPSD	ICGC;COSMIC	10.919	Up-regulation
Other_PLK_PLK1_PLK1_ST	P35568	IRS1	P53350	PLK1	T1045	P1044T	1044	Missense	proximal	-1	no	10.889	11.316	EPSD	ICGC;COSMIC	10.919	Gain
Other_PLK_PLK1_PLK1_ST	P35568	IRS1	P53350	PLK1	S1078	A1071T	1071	Missense	distal	-7	no	11.775	12.120	EPSD	ICGC;GDSC;CCLE	10.919	Up-regulation
Other_PLK_PLK1_PLK1_ST	P35568	IRS1	P53350	PLK1	S1132	D1137N	1137	Missense	distal	5	no	11.149	10.396	EPSD	ICGC	10.919	Loss
Other_PLK_PLK1_PLK1_ST	P35568	IRS1	P53350	PLK1	S1227	R1220H	1220	Missense	distal	-7	no	11.646	12.026	EPSD	ICGC;COSMIC	10.919	Up-regulation
Other_PLK_PLK1_PLK1_ST	P35568	IRS1	P53350	PLK1	S1231	Q1235H	1235	Missense	distal	4	no	14.335	14.229	EPSD	ICGC;COSMIC	10.919	Down-regulation
Other_PLK_PLK1_PLK1_ST	Q49MG5	MAP9	P53350	PLK1	S41	R40M	40	Missense	proximal	-1	no	10.736	11.744	EPSD	ICGC	10.919	Gain
Other_PLK_PLK1_PLK1_ST	Q49MG5	MAP9	P53350	PLK1	S41	S42C	42	Missense	proximal	1	no	10.736	10.971	EPSD	ICGC;COSMIC	10.919	Gain
Other_PLK_PLK1_PLK1_ST	Q49MG5	MAP9	P53350	PLK1	S154	K147E	147	Missense	distal	-7	no	10.858	11.162	EPSD	ICGC;COSMIC	10.919	Gain
Other_PLK_PLK1_PLK1_ST	Q49MG5	MAP9	P53350	PLK1	S165	D167Y	167	Missense	proximal	2	no	11.318	10.951	EPSD	ICGC;COSMIC	10.919	Down-regulation
Other_PLK_PLK1_PLK1_ST	Q49MG5	MAP9	P53350	PLK1	S165	N164K	164	Missense	proximal	-1	no	11.318	10.883	EPSD	ICGC	10.919	Loss
Other_PLK_PLK1_PLK1_ST	Q49MG5	MAP9	P53350	PLK1	S238	L243I	243	Missense	distal	5	no	12.706	13.350	EPSD	ICGC;COSMIC	10.919	Up-regulation
Other_PLK_PLK1_PLK1_ST	Q49MG5	MAP9	P53350	PLK1	S242	L248I	248	Missense	distal	6	no	10.949	10.911	EPSD	ICGC;COSMIC	10.919	Loss
Other_PLK_PLK1_PLK1_ST	Q49MG5	MAP9	P53350	PLK1	S242	L243I	243	Missense	proximal	1	no	10.949	10.741	EPSD	ICGC;COSMIC	10.919	Loss
Other_PLK_PLK1_PLK1_ST	Q49MG5	MAP9	P53350	PLK1	S255	S257P	257	Missense	proximal	2	no	11.924	10.448	EPSD	ICGC	10.919	Loss
Other_PLK_PLK1_PLK1_ST	Q49MG5	MAP9	P53350	PLK1	S255	Q250K	250	Missense	distal	-5	no	11.924	12.126	EPSD	ICGC	10.919	Up-regulation
Other_PLK_PLK1_PLK1_ST	Q49MG5	MAP9	P53350	PLK1	S255	L248I	248	Missense	distal	-7	no	11.924	11.767	EPSD	ICGC;COSMIC	10.919	Down-regulation
Other_PLK_PLK1_PLK1_ST	Q49MG5	MAP9	P53350	PLK1	S255	E261D	261	Missense	distal	6	no	11.924	12.074	EPSD	ICGC;COSMIC	10.919	Up-regulation
Other_PLK_PLK1_PLK1_ST	Q49MG5	MAP9	P53350	PLK1	S289	T296I	296	Missense	distal	7	no	13.258	13.305	PhosphoSitePlus	ICGC	10.919	Up-regulation
Other_PLK_PLK1_PLK1_ST	Q49MG5	MAP9	P53350	PLK1	S336	S336Y	336	Missense	central	0	yes	11.933	0.000	EPSD	ICGC	10.919	Loss
Other_PLK_PLK1_PLK1_ST	Q49MG5	MAP9	P53350	PLK1	S336	S334F	334	Missense	proximal	-2	no	11.933	10.375	EPSD	ICGC;COSMIC	10.919	Loss
Other_PLK_PLK1_PLK1_ST	Q49MG5	MAP9	P53350	PLK1	S338	S336Y	336	Missense	proximal	-2	no	10.115	11.226	EPSD	ICGC	10.919	Gain
Other_PLK_PLK1_PLK1_ST	Q49MG5	MAP9	P53350	PLK1	T364	N360H	360	Missense	distal	-4	no	11.677	11.547	EPSD	ICGC	10.919	Down-regulation
Other_PLK_PLK1_PLK1_ST	Q49MG5	MAP9	P53350	PLK1	S396	S397F	397	Missense	proximal	1	no	8.741	11.789	EPSD	ICGC	10.919	Gain
Other_PLK_PLK1_PLK1_ST	Q49MG5	MAP9	P53350	PLK1	S625	R618Q	618	Missense	distal	-7	no	12.527	12.927	EPSD	ICGC;COSMIC	10.919	Up-regulation
Other_PLK_PLK1_PLK1_ST	Q49MG5	MAP9	P53350	PLK1	S625	E630D	630	Missense	distal	5	no	12.527	12.968	EPSD	ICGC;COSMIC	10.919	Up-regulation
Other_PLK_PLK1_PLK1_ST	Q49MG5	MAP9	P53350	PLK1	S625	L632I	632	Missense	distal	7	no	12.527	12.561	EPSD	ICGC	10.919	Up-regulation
Other_PLK_PLK1_PLK1_ST	Q49MG5	MAP9	P53350	PLK1	S625	K621N	621	Missense	distal	-4	no	12.527	12.785	EPSD	ICGC	10.919	Up-regulation
Other_PLK_PLK1_PLK1_ST	O95613	PCNT	P53350	PLK1	S49	A48V	48	Missense	proximal	-1	no	13.249	12.759	EPSD	ICGC;COSMIC	10.919	Down-regulation
Other_PLK_PLK1_PLK1_ST	O95613	PCNT	P53350	PLK1	S49	S44L	44	Missense	distal	-5	no	13.249	13.913	EPSD	ICGC	10.919	Up-regulation
Other_PLK_PLK1_PLK1_ST	O95613	PCNT	P53350	PLK1	S54	A48V	48	Missense	distal	-6	no	11.950	11.711	EPSD	ICGC;COSMIC	10.919	Down-regulation
Other_PLK_PLK1_PLK1_ST	O95613	PCNT	P53350	PLK1	S61	G67V	67	Missense	distal	6	no	10.676	10.988	EPSD	ICGC	10.919	Gain
Other_PLK_PLK1_PLK1_ST	O95613	PCNT	P53350	PLK1	T78	T73A	73	Missense	distal	-5	no	12.201	12.270	EPSD	ICGC;COSMIC	10.919	Up-regulation
Other_PLK_PLK1_PLK1_ST	O95613	PCNT	P53350	PLK1	T78	D80H	80	Missense	proximal	2	no	12.201	12.177	EPSD	ICGC;COSMIC	10.919	Down-regulation
Other_PLK_PLK1_PLK1_ST	O95613	PCNT	P53350	PLK1	T78	A82S	82	Missense	distal	4	no	12.201	12.399	EPSD	ICGC;COSMIC	10.919	Up-regulation
Other_PLK_PLK1_PLK1_ST	O95613	PCNT	P53350	PLK1	T78	G81E	81	Missense	distal	3	no	12.201	12.377	EPSD	ICGC	10.919	Up-regulation
Other_PLK_PLK1_PLK1_ST	O95613	PCNT	P53350	PLK1	T186	T191P	191	Missense	distal	5	no	10.077	11.069	EPSD	ICGC;COSMIC;CCLE	10.919	Gain
Other_PLK_PLK1_PLK1_ST	O95613	PCNT	P53350	PLK1	T191	R195H	195	Missense	distal	4	no	11.769	12.193	EPSD	ICGC;COSMIC	10.919	Up-regulation
Other_PLK_PLK1_PLK1_ST	O95613	PCNT	P53350	PLK1	T191	T191P	191	Missense	central	0	yes	11.769	0.000	EPSD	ICGC;COSMIC;CCLE	10.919	Loss
Other_PLK_PLK1_PLK1_ST	O95613	PCNT	P53350	PLK1	T539	T539I	539	Missense	central	0	yes	13.475	0.000	EPSD	ICGC;COSMIC	10.919	Loss
Other_PLK_PLK1_PLK1_ST	O95613	PCNT	P53350	PLK1	T539	Q542H	542	Missense	distal	3	no	13.475	13.410	EPSD	ICGC	10.919	Down-regulation
Other_PLK_PLK1_PLK1_ST	O95613	PCNT	P53350	PLK1	T539	R544M	544	Missense	distal	5	no	13.475	13.227	EPSD	ICGC	10.919	Down-regulation
Other_PLK_PLK1_PLK1_ST	O95613	PCNT	P53350	PLK1	T829	H835N	835	Missense	distal	6	no	11.371	11.945	EPSD	ICGC;COSMIC	10.919	Up-regulation
Other_PLK_PLK1_PLK1_ST	O95613	PCNT	P53350	PLK1	T1221	D1219Y	1219	Missense	proximal	-2	no	14.108	12.566	PhosphoSitePlus;EPSD	ICGC	10.919	Down-regulation
Other_PLK_PLK1_PLK1_ST	O95613	PCNT	P53350	PLK1	S1296	T1302I	1302	Missense	distal	6	no	12.290	12.015	EPSD	ICGC	10.919	Down-regulation
Other_PLK_PLK1_PLK1_ST	O95613	PCNT	P53350	PLK1	S1296	S1296G	1296	Missense	central	0	yes	12.290	0.000	EPSD	ICGC;COSMIC	10.919	Loss
Other_PLK_PLK1_PLK1_ST	O95613	PCNT	P53350	PLK1	T1702	T1702M	1702	Missense	central	0	yes	10.980	0.000	EPSD	ICGC;COSMIC	10.919	Loss
Other_PLK_PLK1_PLK1_ST	O95613	PCNT	P53350	PLK1	T2085	R2079H	2079	Missense	distal	-6	no	13.562	14.022	EPSD	ICGC;COSMIC	10.919	Up-regulation
Other_PLK_PLK1_PLK1_ST	O95613	PCNT	P53350	PLK1	T2085	A2091V	2091	Missense	distal	6	no	13.562	13.387	EPSD	ICGC;COSMIC	10.919	Down-regulation
Other_PLK_PLK1_PLK1_ST	O95613	PCNT	P53350	PLK1	S2114	E2119K	2119	Missense	distal	5	no	13.884	13.895	EPSD	ICGC;COSMIC	10.919	Up-regulation
Other_PLK_PLK1_PLK1_ST	O95613	PCNT	P53350	PLK1	S2114	D2112G	2112	Missense	proximal	-2	no	13.884	10.562	EPSD	ICGC;COSMIC	10.919	Loss
Other_PLK_PLK1_PLK1_ST	O95613	PCNT	P53350	PLK1	S2183	M2188R	2188	Missense	distal	5	no	12.264	12.512	EPSD	ICGC;COSMIC	10.919	Up-regulation
Other_PLK_PLK1_PLK1_ST	O95613	PCNT	P53350	PLK1	S2189	P2193L	2193	Missense	distal	4	no	12.182	11.892	EPSD	ICGC;COSMIC;GDSC;CCLE	10.919	Down-regulation
Other_PLK_PLK1_PLK1_ST	O95613	PCNT	P53350	PLK1	S2189	M2188R	2188	Missense	proximal	-1	no	12.182	11.174	EPSD	ICGC;COSMIC	10.919	Down-regulation
Other_PLK_PLK1_PLK1_ST	O95613	PCNT	P53350	PLK1	S2222	P2215L	2215	Missense	distal	-7	no	13.347	13.253	EPSD	ICGC;COSMIC	10.919	Down-regulation
Other_PLK_PLK1_PLK1_ST	O95613	PCNT	P53350	PLK1	S2222	S2222F	2222	Missense	central	0	yes	13.347	0.000	EPSD	ICGC;COSMIC	10.919	Loss
Other_PLK_PLK1_PLK1_ST	O95613	PCNT	P53350	PLK1	S2222	S2223F	2223	Missense	proximal	1	no	13.347	16.395	EPSD	ICGC	10.919	Up-regulation
Other_PLK_PLK1_PLK1_ST	O95613	PCNT	P53350	PLK1	S2372	S2372F	2372	Missense	central	0	yes	11.707	0.000	EPSD	ICGC;COSMIC	10.919	Loss
Other_PLK_PLK1_PLK1_ST	O95613	PCNT	P53350	PLK1	S2372	P2377L	2377	Missense	distal	5	no	11.707	10.973	EPSD	ICGC;COSMIC	10.919	Down-regulation
Other_PLK_PLK1_PLK1_ST	O95613	PCNT	P53350	PLK1	S2372	S2372Y	2372	Missense	central	0	yes	11.707	0.000	EPSD	ICGC;COSMIC	10.919	Loss
Other_PLK_PLK1_PLK1_ST	O95613	PCNT	P53350	PLK1	S2433	G2436V	2436	Missense	distal	3	no	11.190	11.339	EPSD	ICGC;COSMIC	10.919	Up-regulation
Other_PLK_PLK1_PLK1_ST	O95613	PCNT	P53350	PLK1	S2433	T2439M	2439	Missense	distal	6	no	11.190	10.659	EPSD	ICGC;COSMIC	10.919	Loss
Other_PLK_PLK1_PLK1_ST	O95613	PCNT	P53350	PLK1	S2486	L2487V	2487	Missense	proximal	1	no	13.516	13.117	EPSD	ICGC;GDSC	10.919	Down-regulation
Other_PLK_PLK1_PLK1_ST	O95613	PCNT	P53350	PLK1	S2515	Q2522K	2522	Missense	distal	7	no	12.487	12.507	EPSD	ICGC;COSMIC	10.919	Up-regulation
Other_PLK_PLK1_PLK1_ST	O95613	PCNT	P53350	PLK1	T2604	V2606G	2606	Missense	proximal	2	no	11.589	9.804	EPSD	ICGC	10.919	Loss
Other_PLK_PLK1_PLK1_ST	O95613	PCNT	P53350	PLK1	T2604	A2601T	2601	Missense	distal	-3	no	11.589	11.443	EPSD	ICGC;COSMIC	10.919	Down-regulation
Other_PLK_PLK1_PLK1_ST	O95613	PCNT	P53350	PLK1	S2860	R2855Q	2855	Missense	distal	-5	no	11.426	10.687	EPSD	ICGC;GDSC;CCLE	10.919	Loss
Other_PLK_PLK1_PLK1_ST	O95613	PCNT	P53350	PLK1	S2900	A2904V	2904	Missense	distal	4	no	11.419	11.156	EPSD	ICGC;COSMIC	10.919	Down-regulation
Other_PLK_PLK1_PLK1_ST	O95613	PCNT	P53350	PLK1	S2900	A2903T	2903	Missense	distal	3	no	11.419	11.458	EPSD	ICGC;COSMIC	10.919	Up-regulation
Other_PLK_PLK1_PLK1_ST	O95613	PCNT	P53350	PLK1	S3070	S3070I	3070	Missense	central	0	yes	11.391	0.000	EPSD	ICGC	10.919	Loss
Other_PLK_PLK1_PLK1_ST	O95613	PCNT	P53350	PLK1	S3070	E3077Q	3077	Missense	distal	7	no	11.391	11.444	EPSD	ICGC;COSMIC;CCLE	10.919	Up-regulation
Other_PLK_PLK1_PLK1_ST	O95613	PCNT	P53350	PLK1	S3070	T3063S	3063	Missense	distal	-7	no	11.391	11.400	EPSD	ICGC	10.919	Up-regulation
Other_PLK_PLK1_PLK1_ST	O95613	PCNT	P53350	PLK1	S3074	S3070I	3070	Missense	distal	-4	no	11.095	11.129	EPSD	ICGC	10.919	Up-regulation
Other_PLK_PLK1_PLK1_ST	O95613	PCNT	P53350	PLK1	S3074	E3077Q	3077	Missense	distal	3	no	11.095	10.987	EPSD	ICGC;COSMIC;CCLE	10.919	Down-regulation
Other_PLK_PLK1_PLK1_ST	O95613	PCNT	P53350	PLK1	S3292	D3298Y	3298	Missense	distal	6	no	12.598	11.800	EPSD	ICGC;CCLE	10.919	Down-regulation
Other_PLK_PLK1_PLK1_ST	O95613	PCNT	P53350	PLK1	S3296	D3298Y	3298	Missense	proximal	2	no	12.449	12.083	EPSD	ICGC;CCLE	10.919	Down-regulation
Other_PLK_PLK1_PLK1_ST	O95613	PCNT	P53350	PLK1	S3302	E3305D	3305	Missense	distal	3	no	13.950	14.016	EPSD	ICGC	10.919	Up-regulation
Other_PLK_PLK1_PLK1_ST	O95613	PCNT	P53350	PLK1	S3302	D3298Y	3298	Missense	distal	-4	no	13.950	13.458	EPSD	ICGC;CCLE	10.919	Down-regulation
Other_PLK_PLK1_PLK1_ST	O95613	PCNT	P53350	PLK1	S3302	H3309N	3309	Missense	distal	7	no	13.950	14.020	EPSD	ICGC;COSMIC	10.919	Up-regulation
Other_PLK_PLK1_PLK1_ST	O95613	PCNT	P53350	PLK1	S3324	V3320L	3320	Missense	distal	-4	no	11.678	11.585	EPSD	ICGC	10.919	Down-regulation
Other_PLK_PLK1_PLK1_ST	P30307	CDC25C	P53350	PLK1	S38	L33P	33	Missense	distal	-5	no	12.316	11.915	EPSD	ICGC;COSMIC	10.919	Down-regulation
Other_PLK_PLK1_PLK1_ST	P30307	CDC25C	P53350	PLK1	S61	G55S	55	Missense	distal	-6	no	12.984	13.530	EPSD	ICGC;COSMIC	10.919	Up-regulation
Other_PLK_PLK1_PLK1_ST	P30307	CDC25C	P53350	PLK1	S61	A58E	58	Missense	distal	-3	no	12.984	12.293	EPSD	ICGC	10.919	Down-regulation
Other_PLK_PLK1_PLK1_ST	P30307	CDC25C	P53350	PLK1	S75	R70C	70	Missense	distal	-5	no	12.138	11.472	PhosphoSitePlus;EPSD	ICGC;COSMIC	10.919	Down-regulation
Other_PLK_PLK1_PLK1_ST	P30307	CDC25C	P53350	PLK1	S75	S79G	79	Missense	distal	4	no	12.138	12.052	PhosphoSitePlus;EPSD	ICGC;COSMIC	10.919	Down-regulation
Other_PLK_PLK1_PLK1_ST	P30307	CDC25C	P53350	PLK1	S168	T172A	172	Missense	distal	4	no	11.257	11.251	EPSD	ICGC;COSMIC	10.919	Down-regulation
Other_PLK_PLK1_PLK1_ST	P30307	CDC25C	P53350	PLK1	S277	G280W	280	Missense	distal	3	no	12.100	11.745	EPSD	ICGC;COSMIC	10.919	Down-regulation
Other_PLK_PLK1_PLK1_ST	P30307	CDC25C	P53350	PLK1	S451	G456V	456	Missense	distal	5	no	11.295	10.941	EPSD	ICGC;COSMIC	10.919	Down-regulation
Other_PLK_PLK1_PLK1_ST	O43663	PRC1	P53350	PLK1	S70	R64S	64	Missense	distal	-6	no	11.396	11.844	EPSD	ICGC;COSMIC	10.919	Up-regulation
Other_PLK_PLK1_PLK1_ST	O43663	PRC1	P53350	PLK1	T491	R486C	486	Missense	distal	-5	no	11.839	11.174	EPSD	ICGC;COSMIC	10.919	Down-regulation
Other_PLK_PLK1_PLK1_ST	O43663	PRC1	P53350	PLK1	T491	N489K	489	Missense	proximal	-2	no	11.839	9.810	EPSD	ICGC	10.919	Loss
Other_PLK_PLK1_PLK1_ST	O43663	PRC1	P53350	PLK1	S500	R503Q	503	Missense	distal	3	no	11.291	11.486	EPSD	ICGC;COSMIC	10.919	Up-regulation
Other_PLK_PLK1_PLK1_ST	O43663	PRC1	P53350	PLK1	S501	R503Q	503	Missense	proximal	2	no	11.409	11.734	EPSD	ICGC;COSMIC	10.919	Up-regulation
Other_PLK_PLK1_PLK1_ST	O43663	PRC1	P53350	PLK1	S513	Y511C	511	Missense	proximal	-2	no	11.022	7.512	EPSD	ICGC;COSMIC	10.919	Loss
Other_PLK_PLK1_PLK1_ST	O43663	PRC1	P53350	PLK1	S513	R517Q	517	Missense	distal	4	no	11.022	11.552	EPSD	ICGC;COSMIC;GDSC;CCLE	10.919	Up-regulation
Other_PLK_PLK1_PLK1_ST	O43663	PRC1	P53350	PLK1	S513	P520L	520	Missense	distal	7	no	11.022	10.993	EPSD	ICGC	10.919	Down-regulation
Other_PLK_PLK1_PLK1_ST	O43663	PRC1	P53350	PLK1	S513	P514L	514	Missense	proximal	1	no	11.022	11.868	EPSD	ICGC	10.919	Up-regulation
Other_PLK_PLK1_PLK1_ST	O43663	PRC1	P53350	PLK1	S554	G553S	553	Missense	proximal	-1	no	11.834	13.632	EPSD	ICGC;COSMIC	10.919	Up-regulation
Other_PLK_PLK1_PLK1_ST	O43663	PRC1	P53350	PLK1	S554	N548K	548	Missense	distal	-6	no	11.834	11.576	EPSD	ICGC	10.919	Down-regulation
Other_PLK_PLK1_PLK1_ST	O43663	PRC1	P53350	PLK1	S554	P561L	561	Missense	distal	7	no	11.834	11.805	EPSD	ICGC;COSMIC	10.919	Down-regulation
Other_PLK_PLK1_PLK1_ST	O43663	PRC1	P53350	PLK1	S587	D590E	590	Missense	distal	3	no	14.025	13.960	EPSD	ICGC;COSMIC	10.919	Down-regulation
Other_PLK_PLK1_PLK1_ST	O43663	PRC1	P53350	PLK1	S587	A583V	583	Missense	distal	-4	no	14.025	13.885	EPSD	ICGC	10.919	Down-regulation
Other_PLK_PLK1_PLK1_ST	O43663	PRC1	P53350	PLK1	S601	R598Q	598	Missense	distal	-3	no	14.240	13.565	EPSD	ICGC;COSMIC	10.919	Down-regulation
Other_PLK_PLK1_PLK1_ST	O43663	PRC1	P53350	PLK1	S601	L600I	600	Missense	proximal	-1	no	14.240	14.716	EPSD	ICGC	10.919	Up-regulation
Other_PLK_PLK1_PLK1_ST	O43663	PRC1	P53350	PLK1	T616	N617K	617	Missense	proximal	1	no	12.726	12.226	PhosphoSitePlus;EPSD	ICGC	10.919	Down-regulation
Other_PLK_PLK1_PLK1_ST	Q7L2Z9	CENPQ	P53350	PLK1	S50	S51F	51	Missense	proximal	1	no	8.947	11.996	EPSD	ICGC;COSMIC	10.919	Gain
Other_PLK_PLK1_PLK1_ST	Q7L2Z9	CENPQ	P53350	PLK1	T135	V137L	137	Missense	proximal	2	no	11.453	11.320	EPSD;PhosphoSitePlus	ICGC	10.919	Down-regulation
Other_PLK_PLK1_PLK1_ST	Q7L2Z9	CENPQ	P53350	PLK1	T135	L134V	134	Missense	proximal	-1	no	11.453	10.955	EPSD;PhosphoSitePlus	ICGC;COSMIC	10.919	Down-regulation
Other_PLK_PLK1_PLK1_ST	Q7L2Z9	CENPQ	P53350	PLK1	S138	V137L	137	Missense	proximal	-1	no	12.249	12.746	EPSD;PhosphoSitePlus	ICGC	10.919	Up-regulation
Other_PLK_PLK1_PLK1_ST	Q7L2Z9	CENPQ	P53350	PLK1	S138	L134V	134	Missense	distal	-4	no	12.249	12.342	EPSD;PhosphoSitePlus	ICGC;COSMIC	10.919	Up-regulation
Other_PLK_PLK1_PLK1_ST	Q7L2Z9	CENPQ	P53350	PLK1	S248	N247D	247	Missense	proximal	-1	no	10.306	11.239	EPSD;PhosphoSitePlus	ICGC;COSMIC	10.919	Gain
Other_PLK_PLK1_PLK1_ST	Q7L2Z9	CENPQ	P53350	PLK1	S249	M254I	254	Missense	distal	5	no	14.494	14.695	EPSD;PhosphoSitePlus	ICGC;COSMIC	10.919	Up-regulation
Other_PLK_PLK1_PLK1_ST	Q7L2Z9	CENPQ	P53350	PLK1	S249	L242F	242	Missense	distal	-7	no	14.494	14.342	EPSD;PhosphoSitePlus	ICGC;COSMIC	10.919	Down-regulation
Other_PLK_PLK1_PLK1_ST	Q7L2Z9	CENPQ	P53350	PLK1	S249	N247D	247	Missense	proximal	-2	no	14.494	15.737	EPSD;PhosphoSitePlus	ICGC;COSMIC	10.919	Up-regulation
Other_PLK_PLK1_PLK1_ST	Q7L2Z9	CENPQ	P53350	PLK1	S253	M254I	254	Missense	proximal	1	no	12.568	11.603	EPSD;PhosphoSitePlus	ICGC;COSMIC	10.919	Down-regulation
Other_PLK_PLK1_PLK1_ST	Q7L2Z9	CENPQ	P53350	PLK1	S253	E259K	259	Missense	distal	6	no	12.568	12.499	EPSD;PhosphoSitePlus	ICGC;COSMIC	10.919	Down-regulation
Other_PLK_PLK1_PLK1_ST	Q7L2Z9	CENPQ	P53350	PLK1	S253	N247D	247	Missense	distal	-6	no	12.568	12.681	EPSD;PhosphoSitePlus	ICGC;COSMIC	10.919	Up-regulation
Other_PLK_PLK1_PLK1_ST	Q7L2Z9	CENPQ	P53350	PLK1	S255	M254I	254	Missense	proximal	-1	no	11.102	11.048	PhosphoSitePlus;EPSD	ICGC;COSMIC	10.919	Down-regulation
Other_PLK_PLK1_PLK1_ST	Q7L2Z9	CENPQ	P53350	PLK1	S255	A261S	261	Missense	distal	6	no	11.102	10.819	PhosphoSitePlus;EPSD	ICGC	10.919	Loss
Other_PLK_PLK1_PLK1_ST	Q7L2Z9	CENPQ	P53350	PLK1	S255	E259K	259	Missense	distal	4	no	11.102	10.729	PhosphoSitePlus;EPSD	ICGC;COSMIC	10.919	Loss
Other_PLK_PLK1_PLK1_ST	Q7L2Z9	CENPQ	P53350	PLK1	T256	M254I	254	Missense	proximal	-2	no	14.680	14.573	EPSD;PhosphoSitePlus	ICGC;COSMIC	10.919	Down-regulation
Other_PLK_PLK1_PLK1_ST	Q7L2Z9	CENPQ	P53350	PLK1	T256	A261S	261	Missense	distal	5	no	14.680	14.114	EPSD;PhosphoSitePlus	ICGC	10.919	Down-regulation
Other_PLK_PLK1_PLK1_ST	Q7L2Z9	CENPQ	P53350	PLK1	T256	Y262N	262	Missense	distal	6	no	14.680	15.259	EPSD;PhosphoSitePlus	ICGC	10.919	Up-regulation
Other_PLK_PLK1_PLK1_ST	Q7L2Z9	CENPQ	P53350	PLK1	T256	E259K	259	Missense	distal	3	no	14.680	14.474	EPSD;PhosphoSitePlus	ICGC;COSMIC	10.919	Down-regulation
Other_PLK_PLK1_PLK1_ST	Q8IZD2	KMT2E	P53350	PLK1	S15	T11I	11	Missense	distal	-4	no	10.832	11.228	EPSD	ICGC;COSMIC	10.919	Gain
Other_PLK_PLK1_PLK1_ST	Q8IZD2	KMT2E	P53350	PLK1	S265	G268V	268	Missense	distal	3	no	12.689	12.837	EPSD	ICGC;COSMIC	10.919	Up-regulation
Other_PLK_PLK1_PLK1_ST	Q8IZD2	KMT2E	P53350	PLK1	S265	S265A	265	Missense	central	0	yes	12.689	0.000	EPSD	ICGC;COSMIC	10.919	Loss
Other_PLK_PLK1_PLK1_ST	Q8IZD2	KMT2E	P53350	PLK1	S265	P264H	264	Missense	proximal	-1	no	12.689	13.923	EPSD	ICGC;COSMIC	10.919	Up-regulation
Other_PLK_PLK1_PLK1_ST	Q8IZD2	KMT2E	P53350	PLK1	S499	G492E	492	Missense	distal	-7	no	12.233	12.869	EPSD	ICGC;COSMIC	10.919	Up-regulation
Other_PLK_PLK1_PLK1_ST	Q8IZD2	KMT2E	P53350	PLK1	T510	D512Y	512	Missense	proximal	2	no	11.744	11.378	EPSD	ICGC	10.919	Down-regulation
Other_PLK_PLK1_PLK1_ST	Q8IZD2	KMT2E	P53350	PLK1	S653	N646S	646	Missense	distal	-7	no	10.743	10.953	EPSD	ICGC;COSMIC	10.919	Gain
Other_PLK_PLK1_PLK1_ST	Q8IZD2	KMT2E	P53350	PLK1	S829	A823S	823	Missense	distal	-6	no	11.883	11.918	EPSD	ICGC	10.919	Up-regulation
Other_PLK_PLK1_PLK1_ST	Q8IZD2	KMT2E	P53350	PLK1	S885	S882L	882	Missense	distal	-3	no	12.506	13.280	EPSD	ICGC;COSMIC	10.919	Up-regulation
Other_PLK_PLK1_PLK1_ST	Q8IZD2	KMT2E	P53350	PLK1	S909	P908T	908	Missense	proximal	-1	no	15.640	16.066	EPSD	ICGC;COSMIC	10.919	Up-regulation
Other_PLK_PLK1_PLK1_ST	Q8IZD2	KMT2E	P53350	PLK1	S909	P914L	914	Missense	distal	5	no	15.640	14.906	EPSD	ICGC;COSMIC	10.919	Down-regulation
Other_PLK_PLK1_PLK1_ST	Q8IZD2	KMT2E	P53350	PLK1	S909	M906L	906	Missense	distal	-3	no	15.640	16.162	EPSD	ICGC;COSMIC	10.919	Up-regulation
Other_PLK_PLK1_PLK1_ST	Q8IZD2	KMT2E	P53350	PLK1	S966	R963L	963	Missense	distal	-3	no	11.434	11.376	EPSD	ICGC	10.919	Down-regulation
Other_PLK_PLK1_PLK1_ST	Q8IZD2	KMT2E	P53350	PLK1	T1062	R1060W	1060	Missense	proximal	-2	no	11.152	4.493	EPSD	ICGC;COSMIC	10.919	Loss
Other_PLK_PLK1_PLK1_ST	Q8IZD2	KMT2E	P53350	PLK1	T1062	S1065F	1065	Missense	distal	3	no	11.152	11.211	EPSD	ICGC;COSMIC	10.919	Up-regulation
Other_PLK_PLK1_PLK1_ST	Q8IZD2	KMT2E	P53350	PLK1	S1066	R1060W	1060	Missense	distal	-6	no	11.645	11.188	EPSD	ICGC;COSMIC	10.919	Down-regulation
Other_PLK_PLK1_PLK1_ST	Q8IZD2	KMT2E	P53350	PLK1	S1066	S1065F	1065	Missense	proximal	-1	no	11.645	11.106	EPSD	ICGC;COSMIC	10.919	Down-regulation
Other_PLK_PLK1_PLK1_ST	Q8IZD2	KMT2E	P53350	PLK1	T1088	T1088A	1088	Missense	central	0	yes	11.129	0.000	EPSD	ICGC;COSMIC	10.919	Loss
Other_PLK_PLK1_PLK1_ST	Q8IZD2	KMT2E	P53350	PLK1	S1297	S1298F	1298	Missense	proximal	1	no	8.872	11.920	EPSD	ICGC	10.919	Gain
Other_PLK_PLK1_PLK1_ST	Q9Y6D9	MAD1L1	P53350	PLK1	T8	G5R	5	Missense	distal	-3	no	12.736	12.795	EPSD	ICGC	10.919	Up-regulation
Other_PLK_PLK1_PLK1_ST	Q9Y6D9	MAD1L1	P53350	PLK1	S266	E271D	271	Missense	distal	5	no	10.848	11.289	EPSD	ICGC;COSMIC	10.919	Gain
Other_PLK_PLK1_PLK1_ST	Q9Y6D9	MAD1L1	P53350	PLK1	S420	E426Q	426	Missense	distal	6	no	13.823	13.683	EPSD	ICGC;COSMIC	10.919	Down-regulation
Other_PLK_PLK1_PLK1_ST	Q9Y6D9	MAD1L1	P53350	PLK1	S428	E426Q	426	Missense	proximal	-2	no	13.971	11.312	EPSD	ICGC;COSMIC	10.919	Down-regulation
Other_PLK_PLK1_PLK1_ST	Q9Y6D9	MAD1L1	P53350	PLK1	S562	R558Q	558	Missense	distal	-4	no	10.942	11.230	EPSD	ICGC;COSMIC	10.919	Up-regulation
Other_PLK_PLK1_PLK1_ST	Q99708	RBBP8	P53350	PLK1	S17	S10I	10	Missense	distal	-7	no	12.525	12.063	EPSD	ICGC;COSMIC	10.919	Down-regulation
Other_PLK_PLK1_PLK1_ST	Q99708	RBBP8	P53350	PLK1	S17	A14S	14	Missense	distal	-3	no	12.525	12.003	EPSD	ICGC	10.919	Down-regulation
Other_PLK_PLK1_PLK1_ST	Q99708	RBBP8	P53350	PLK1	S163	P164L	164	Missense	proximal	1	no	10.099	10.945	EPSD	ICGC;COSMIC	10.919	Gain
Other_PLK_PLK1_PLK1_ST	Q99708	RBBP8	P53350	PLK1	S231	D226E	226	Missense	distal	-5	no	12.346	12.005	EPSD	ICGC;COSMIC	10.919	Down-regulation
Other_PLK_PLK1_PLK1_ST	Q99708	RBBP8	P53350	PLK1	S231	T227I	227	Missense	distal	-4	no	12.346	12.742	EPSD	ICGC	10.919	Up-regulation
Other_PLK_PLK1_PLK1_ST	Q99708	RBBP8	P53350	PLK1	S231	M235I	235	Missense	distal	4	no	12.346	12.104	EPSD	ICGC;COSMIC	10.919	Down-regulation
Other_PLK_PLK1_PLK1_ST	Q99708	RBBP8	P53350	PLK1	S231	S231I	231	Missense	central	0	yes	12.346	0.000	EPSD	ICGC	10.919	Loss
Other_PLK_PLK1_PLK1_ST	Q99708	RBBP8	P53350	PLK1	S305	S298Y	298	Missense	distal	-7	no	14.092	13.480	EPSD	ICGC	10.919	Down-regulation
Other_PLK_PLK1_PLK1_ST	Q99708	RBBP8	P53350	PLK1	S311	T315P	315	Missense	distal	4	no	11.283	11.154	EPSD	ICGC	10.919	Down-regulation
Other_PLK_PLK1_PLK1_ST	Q99708	RBBP8	P53350	PLK1	S349	K355E	355	Missense	distal	6	no	11.566	11.635	EPSD	ICGC;COSMIC	10.919	Up-regulation
Other_PLK_PLK1_PLK1_ST	Q99708	RBBP8	P53350	PLK1	S454	R447W	447	Missense	distal	-7	no	10.691	11.277	EPSD	ICGC	10.919	Gain
Other_PLK_PLK1_PLK1_ST	Q99708	RBBP8	P53350	PLK1	S454	T450S	450	Missense	distal	-4	no	10.691	11.053	EPSD	ICGC;COSMIC	10.919	Gain
Other_PLK_PLK1_PLK1_ST	Q99708	RBBP8	P53350	PLK1	S549	K547E	547	Missense	proximal	-2	no	9.530	12.407	EPSD	ICGC;COSMIC	10.919	Gain
Other_PLK_PLK1_PLK1_ST	Q99708	RBBP8	P53350	PLK1	S549	G551W	551	Missense	proximal	2	no	9.530	11.129	EPSD	ICGC;COSMIC	10.919	Gain
Other_PLK_PLK1_PLK1_ST	Q99708	RBBP8	P53350	PLK1	S679	G678D	678	Missense	proximal	-1	no	10.362	12.952	EPSD	ICGC;COSMIC	10.919	Gain
Other_PLK_PLK1_PLK1_ST	Q15022	SUZ12	P53350	PLK1	S384	L377I	377	Missense	distal	-7	no	12.886	12.729	EPSD	ICGC;COSMIC	10.919	Down-regulation
Other_PLK_PLK1_PLK1_ST	Q15022	SUZ12	P53350	PLK1	S384	N389T	389	Missense	distal	5	no	12.886	12.885	EPSD	ICGC;COSMIC	10.919	Down-regulation
Other_PLK_PLK1_PLK1_ST	Q15022	SUZ12	P53350	PLK1	S384	E383G	383	Missense	proximal	-1	no	12.886	11.092	EPSD	ICGC;COSMIC	10.919	Down-regulation
Other_PLK_PLK1_PLK1_ST	Q15022	SUZ12	P53350	PLK1	S384	H386N	386	Missense	proximal	2	no	12.886	13.125	EPSD	ICGC;COSMIC	10.919	Up-regulation
Other_PLK_PLK1_PLK1_ST	Q15022	SUZ12	P53350	PLK1	S604	E602D	602	Missense	proximal	-2	no	11.616	12.010	EPSD	ICGC	10.919	Up-regulation
Other_PLK_PLK1_PLK1_ST	Q15022	SUZ12	P53350	PLK1	S726	Q733H	733	Missense	distal	7	no	13.282	13.238	EPSD	ICGC;COSMIC	10.919	Down-regulation
Other_PLK_PLK1_PLK1_ST	Q9BVS4	RIOK2	P53350	PLK1	S36	A39D	39	Missense	distal	3	no	10.680	11.101	EPSD	ICGC	10.919	Gain
Other_PLK_PLK1_PLK1_ST	Q9BVS4	RIOK2	P53350	PLK1	S131	H125Q	125	Missense	distal	-6	no	11.981	11.969	EPSD	ICGC;COSMIC	10.919	Down-regulation
Other_PLK_PLK1_PLK1_ST	Q9BVS4	RIOK2	P53350	PLK1	S131	S131P	131	Missense	central	0	yes	11.981	0.000	EPSD	ICGC;COSMIC	10.919	Loss
Other_PLK_PLK1_PLK1_ST	Q9BVS4	RIOK2	P53350	PLK1	S335	T328K	328	Missense	distal	-7	no	14.806	14.450	PhosphoSitePlus;EPSD	ICGC	10.919	Down-regulation
Other_PLK_PLK1_PLK1_ST	Q9BVS4	RIOK2	P53350	PLK1	S380	D387N	387	Missense	distal	7	no	14.193	14.275	EPSD;PhosphoSitePlus	ICGC;COSMIC	10.919	Up-regulation
Other_PLK_PLK1_PLK1_ST	Q9BVS4	RIOK2	P53350	PLK1	S380	A386V	386	Missense	distal	6	no	14.193	14.018	EPSD;PhosphoSitePlus	ICGC;COSMIC	10.919	Down-regulation
Other_PLK_PLK1_PLK1_ST	Q9BVS4	RIOK2	P53350	PLK1	S385	A386V	386	Missense	proximal	1	no	9.967	11.405	EPSD	ICGC;COSMIC	10.919	Gain
Other_PLK_PLK1_PLK1_ST	Q9BVS4	RIOK2	P53350	PLK1	S457	F462S	462	Missense	distal	5	no	12.037	11.943	EPSD	ICGC;COSMIC	10.919	Down-regulation
Other_PLK_PLK1_PLK1_ST	Q9BVS4	RIOK2	P53350	PLK1	S457	R463K	463	Missense	distal	6	no	12.037	12.397	EPSD	ICGC;COSMIC	10.919	Up-regulation
Other_PLK_PLK1_PLK1_ST	Q9BVS4	RIOK2	P53350	PLK1	S457	E461K	461	Missense	distal	4	no	12.037	11.663	EPSD	ICGC	10.919	Down-regulation
Other_PLK_PLK1_PLK1_ST	Q9BVS4	RIOK2	P53350	PLK1	S483	T485A	485	Missense	proximal	2	no	10.787	11.187	EPSD	ICGC;COSMIC	10.919	Gain
Other_PLK_PLK1_PLK1_ST	Q9BVS4	RIOK2	P53350	PLK1	S548	S543T	543	Missense	distal	-5	no	12.055	12.270	EPSD;PhosphoSitePlus	ICGC	10.919	Up-regulation
Other_PLK_PLK1_PLK1_ST	Q9BVS4	RIOK2	P53350	PLK1	S548	W550C	550	Missense	proximal	2	no	12.055	11.064	EPSD;PhosphoSitePlus	ICGC;COSMIC	10.919	Down-regulation
Other_PLK_PLK1_PLK1_ST	Q14676	MDC1	P53350	PLK1	S23	R25M	25	Missense	proximal	2	no	10.593	11.319	EPSD	ICGC	10.919	Gain
Other_PLK_PLK1_PLK1_ST	Q14676	MDC1	P53350	PLK1	S136	R142L	142	Missense	distal	6	no	10.680	11.027	EPSD	ICGC;COSMIC	10.919	Gain
Other_PLK_PLK1_PLK1_ST	Q14676	MDC1	P53350	PLK1	S292	D298N	298	Missense	distal	6	no	10.929	10.709	EPSD	ICGC;COSMIC	10.919	Loss
Other_PLK_PLK1_PLK1_ST	Q14676	MDC1	P53350	PLK1	S299	D298N	298	Missense	proximal	-1	no	11.763	10.830	EPSD	ICGC;COSMIC	10.919	Loss
Other_PLK_PLK1_PLK1_ST	Q14676	MDC1	P53350	PLK1	S372	E371K	371	Missense	proximal	-1	no	11.301	10.730	EPSD	ICGC;COSMIC	10.919	Loss
Other_PLK_PLK1_PLK1_ST	Q14676	MDC1	P53350	PLK1	S372	H368N	368	Missense	distal	-4	no	11.301	11.432	EPSD	ICGC;COSMIC	10.919	Up-regulation
Other_PLK_PLK1_PLK1_ST	Q14676	MDC1	P53350	PLK1	T378	E371K	371	Missense	distal	-7	no	13.390	13.086	EPSD	ICGC;COSMIC	10.919	Down-regulation
Other_PLK_PLK1_PLK1_ST	Q14676	MDC1	P53350	PLK1	T548	G547W	547	Missense	proximal	-1	no	11.319	10.890	EPSD	ICGC;COSMIC	10.919	Loss
Other_PLK_PLK1_PLK1_ST	Q14676	MDC1	P53350	PLK1	S763	D769G	769	Missense	distal	6	no	11.461	10.985	EPSD	ICGC;COSMIC	10.919	Down-regulation
Other_PLK_PLK1_PLK1_ST	Q14676	MDC1	P53350	PLK1	S1195	S1194Y	1194	Missense	proximal	-1	no	11.095	11.431	EPSD	ICGC	10.919	Up-regulation
Other_PLK_PLK1_PLK1_ST	Q14676	MDC1	P53350	PLK1	S1277	S1276P	1276	Missense	proximal	-1	no	11.426	10.252	EPSD	ICGC	10.919	Loss
Other_PLK_PLK1_PLK1_ST	Q14676	MDC1	P53350	PLK1	S1294	R1292Q	1292	Missense	proximal	-2	no	12.009	11.833	EPSD	ICGC;COSMIC	10.919	Down-regulation
Other_PLK_PLK1_PLK1_ST	Q14676	MDC1	P53350	PLK1	S1335	V1342F	1342	Missense	distal	7	no	12.729	12.751	EPSD	ICGC	10.919	Up-regulation
Other_PLK_PLK1_PLK1_ST	Q14676	MDC1	P53350	PLK1	T1366	T1366I	1366	Missense	central	0	yes	11.738	0.000	EPSD	ICGC	10.919	Loss
Other_PLK_PLK1_PLK1_ST	Q14676	MDC1	P53350	PLK1	S1522	S1522P	1522	Missense	central	0	yes	11.593	0.000	EPSD	ICGC	10.919	Loss
Other_PLK_PLK1_PLK1_ST	Q14676	MDC1	P53350	PLK1	S1523	S1522P	1522	Missense	proximal	-1	no	11.802	10.628	EPSD	ICGC	10.919	Loss
Other_PLK_PLK1_PLK1_ST	Q14676	MDC1	P53350	PLK1	T1541	S1542F	1542	Missense	proximal	1	no	8.487	11.536	EPSD	ICGC	10.919	Gain
Other_PLK_PLK1_PLK1_ST	Q14676	MDC1	P53350	PLK1	S1658	P1655R	1655	Missense	distal	-3	no	10.824	12.074	EPSD	ICGC;COSMIC	10.919	Gain
Other_PLK_PLK1_PLK1_ST	Q14676	MDC1	P53350	PLK1	T1768	A1769V	1769	Missense	proximal	1	no	9.645	11.083	EPSD	ICGC;COSMIC	10.919	Gain
Other_PLK_PLK1_PLK1_ST	Q14676	MDC1	P53350	PLK1	S1924	S1924Y	1924	Missense	central	0	yes	12.058	0.000	EPSD	ICGC	10.919	Loss
Other_PLK_PLK1_PLK1_ST	O00139	KIF2A	P53350	PLK1	S135	Q131K	131	Missense	distal	-4	no	11.374	11.260	EPSD	ICGC;COSMIC	10.919	Down-regulation
Other_PLK_PLK1_PLK1_ST	P30260	CDC27	P53350	PLK1	T200	S194C	194	Missense	distal	-6	no	10.943	9.740	EPSD	ICGC;COSMIC	10.919	Loss
Other_PLK_PLK1_PLK1_ST	P30260	CDC27	P53350	PLK1	T200	T205I	205	Missense	distal	5	no	10.943	11.845	EPSD	ICGC;COSMIC	10.919	Up-regulation
Other_PLK_PLK1_PLK1_ST	P30260	CDC27	P53350	PLK1	T200	V201I	201	Missense	proximal	1	no	10.943	11.134	EPSD	ICGC;COSMIC	10.919	Up-regulation
Other_PLK_PLK1_PLK1_ST	P30260	CDC27	P53350	PLK1	T205	T205I	205	Missense	central	0	yes	12.506	0.000	EPSD;PhosphoSitePlus	ICGC;COSMIC	10.919	Loss
Other_PLK_PLK1_PLK1_ST	P30260	CDC27	P53350	PLK1	T205	D208Y	208	Missense	distal	3	no	12.506	12.080	EPSD;PhosphoSitePlus	ICGC;COSMIC	10.919	Down-regulation
Other_PLK_PLK1_PLK1_ST	P30260	CDC27	P53350	PLK1	T205	V201I	201	Missense	distal	-4	no	12.506	12.640	EPSD;PhosphoSitePlus	ICGC;COSMIC	10.919	Up-regulation
Other_PLK_PLK1_PLK1_ST	P30260	CDC27	P53350	PLK1	S225	S231P	231	Missense	distal	6	no	11.754	11.898	EPSD	ICGC;COSMIC	10.919	Up-regulation
Other_PLK_PLK1_PLK1_ST	P30260	CDC27	P53350	PLK1	S225	S230Y	230	Missense	distal	5	no	11.754	11.597	EPSD	ICGC;COSMIC	10.919	Down-regulation
Other_PLK_PLK1_PLK1_ST	P30260	CDC27	P53350	PLK1	S231	I235T	235	Missense	distal	4	no	13.803	14.802	EPSD	ICGC;COSMIC	10.919	Up-regulation
Other_PLK_PLK1_PLK1_ST	P30260	CDC27	P53350	PLK1	S231	Y234S	234	Missense	distal	3	no	13.803	13.983	EPSD	ICGC;COSMIC	10.919	Up-regulation
Other_PLK_PLK1_PLK1_ST	P30260	CDC27	P53350	PLK1	S231	S231P	231	Missense	central	0	yes	13.803	0.000	EPSD	ICGC;COSMIC	10.919	Loss
Other_PLK_PLK1_PLK1_ST	P30260	CDC27	P53350	PLK1	S231	S230Y	230	Missense	proximal	-1	no	13.803	14.139	EPSD	ICGC;COSMIC	10.919	Up-regulation
Other_PLK_PLK1_PLK1_ST	P30260	CDC27	P53350	PLK1	S237	I235T	235	Missense	proximal	-2	no	12.206	12.231	EPSD	ICGC;COSMIC	10.919	Up-regulation
Other_PLK_PLK1_PLK1_ST	P30260	CDC27	P53350	PLK1	S237	Y234S	234	Missense	distal	-3	no	12.206	11.737	EPSD	ICGC;COSMIC	10.919	Down-regulation
Other_PLK_PLK1_PLK1_ST	P30260	CDC27	P53350	PLK1	S237	S231P	231	Missense	distal	-6	no	12.206	11.583	EPSD	ICGC;COSMIC	10.919	Down-regulation
Other_PLK_PLK1_PLK1_ST	P30260	CDC27	P53350	PLK1	S237	P242S	242	Missense	distal	5	no	12.206	11.819	EPSD	ICGC;COSMIC	10.919	Down-regulation
Other_PLK_PLK1_PLK1_ST	P30260	CDC27	P53350	PLK1	S237	S230Y	230	Missense	distal	-7	no	12.206	11.594	EPSD	ICGC;COSMIC	10.919	Down-regulation
Other_PLK_PLK1_PLK1_ST	P30260	CDC27	P53350	PLK1	S241	I235T	235	Missense	distal	-6	no	11.820	11.648	EPSD	ICGC;COSMIC	10.919	Down-regulation
Other_PLK_PLK1_PLK1_ST	P30260	CDC27	P53350	PLK1	S241	Y234S	234	Missense	distal	-7	no	11.820	12.432	EPSD	ICGC;COSMIC	10.919	Up-regulation
Other_PLK_PLK1_PLK1_ST	P30260	CDC27	P53350	PLK1	S241	P242S	242	Missense	proximal	1	no	11.820	10.698	EPSD	ICGC;COSMIC	10.919	Loss
Other_PLK_PLK1_PLK1_ST	P30260	CDC27	P53350	PLK1	S276	A274D	274	Missense	proximal	-2	no	8.964	11.536	EPSD	ICGC;COSMIC	10.919	Gain
Other_PLK_PLK1_PLK1_ST	P30260	CDC27	P53350	PLK1	T343	I345V	345	Missense	proximal	2	no	11.831	11.613	EPSD	ICGC;COSMIC	10.919	Down-regulation
Other_PLK_PLK1_PLK1_ST	P30260	CDC27	P53350	PLK1	T343	S336R	336	Missense	distal	-7	no	11.831	11.334	EPSD	ICGC;COSMIC	10.919	Down-regulation
Other_PLK_PLK1_PLK1_ST	P30260	CDC27	P53350	PLK1	T343	N338K	338	Missense	distal	-5	no	11.831	12.029	EPSD	ICGC;COSMIC	10.919	Up-regulation
Other_PLK_PLK1_PLK1_ST	P30260	CDC27	P53350	PLK1	T343	L346I	346	Missense	distal	3	no	11.831	12.006	EPSD	ICGC;COSMIC	10.919	Up-regulation
Other_PLK_PLK1_PLK1_ST	P30260	CDC27	P53350	PLK1	T343	L346F	346	Missense	distal	3	no	11.831	12.037	EPSD	ICGC;COSMIC	10.919	Up-regulation
Other_PLK_PLK1_PLK1_ST	P30260	CDC27	P53350	PLK1	T343	Q348K	348	Missense	distal	5	no	11.831	12.001	EPSD	ICGC;COSMIC	10.919	Up-regulation
Other_PLK_PLK1_PLK1_ST	P30260	CDC27	P53350	PLK1	T343	N338S	338	Missense	distal	-5	no	11.831	11.883	EPSD	ICGC;COSMIC	10.919	Up-regulation
Other_PLK_PLK1_PLK1_ST	P30260	CDC27	P53350	PLK1	T349	T356I	356	Missense	distal	7	no	10.889	10.936	EPSD	ICGC;COSMIC	10.919	Gain
Other_PLK_PLK1_PLK1_ST	P30260	CDC27	P53350	PLK1	T349	T356A	356	Missense	distal	7	no	10.889	10.929	EPSD	ICGC;COSMIC	10.919	Gain
Other_PLK_PLK1_PLK1_ST	P30260	CDC27	P53350	PLK1	S386	S384N	384	Missense	proximal	-2	no	9.695	11.105	EPSD	ICGC;COSMIC	10.919	Gain
Other_PLK_PLK1_PLK1_ST	P30260	CDC27	P53350	PLK1	S393	T389N	389	Missense	distal	-4	no	10.865	11.092	EPSD	ICGC;COSMIC	10.919	Gain
Other_PLK_PLK1_PLK1_ST	P30260	CDC27	P53350	PLK1	S393	K395Q	395	Missense	proximal	2	no	10.865	11.223	EPSD	ICGC;COSMIC	10.919	Gain
Other_PLK_PLK1_PLK1_ST	P30260	CDC27	P53350	PLK1	S426	S426G	426	Missense	central	0	yes	12.969	0.000	EPSD;PhosphoSitePlus	ICGC;COSMIC	10.919	Loss
Other_PLK_PLK1_PLK1_ST	P30260	CDC27	P53350	PLK1	S426	N424D	424	Missense	proximal	-2	no	12.969	14.212	EPSD;PhosphoSitePlus	ICGC;COSMIC	10.919	Up-regulation
Other_PLK_PLK1_PLK1_ST	P30260	CDC27	P53350	PLK1	S426	I429V	429	Missense	distal	3	no	12.969	13.092	EPSD;PhosphoSitePlus	ICGC;COSMIC	10.919	Up-regulation
Other_PLK_PLK1_PLK1_ST	P30260	CDC27	P53350	PLK1	S426	I429M	429	Missense	distal	3	no	12.969	12.651	EPSD;PhosphoSitePlus	ICGC;COSMIC	10.919	Down-regulation
Other_PLK_PLK1_PLK1_ST	P30260	CDC27	P53350	PLK1	S426	N424S	424	Missense	proximal	-2	no	12.969	11.560	EPSD;PhosphoSitePlus	ICGC;COSMIC	10.919	Down-regulation
Other_PLK_PLK1_PLK1_ST	P30260	CDC27	P53350	PLK1	S426	Q420P	420	Missense	distal	-6	no	12.969	12.346	EPSD;PhosphoSitePlus	ICGC;COSMIC	10.919	Down-regulation
Other_PLK_PLK1_PLK1_ST	P30260	CDC27	P53350	PLK1	S426	S426N	426	Missense	central	0	yes	12.969	0.000	EPSD;PhosphoSitePlus	ICGC	10.919	Loss
Other_PLK_PLK1_PLK1_ST	P30260	CDC27	P53350	PLK1	T430	S435F	435	Missense	distal	5	no	13.602	13.696	EPSD;PhosphoSitePlus	ICGC;COSMIC	10.919	Up-regulation
Other_PLK_PLK1_PLK1_ST	P30260	CDC27	P53350	PLK1	T430	S426G	426	Missense	distal	-4	no	13.602	12.948	EPSD;PhosphoSitePlus	ICGC;COSMIC	10.919	Down-regulation
Other_PLK_PLK1_PLK1_ST	P30260	CDC27	P53350	PLK1	T430	N424D	424	Missense	distal	-6	no	13.602	13.715	EPSD;PhosphoSitePlus	ICGC;COSMIC	10.919	Up-regulation
Other_PLK_PLK1_PLK1_ST	P30260	CDC27	P53350	PLK1	T430	I429V	429	Missense	proximal	-1	no	13.602	12.628	EPSD;PhosphoSitePlus	ICGC;COSMIC	10.919	Down-regulation
Other_PLK_PLK1_PLK1_ST	P30260	CDC27	P53350	PLK1	T430	I429M	429	Missense	proximal	-1	no	13.602	13.657	EPSD;PhosphoSitePlus	ICGC;COSMIC	10.919	Up-regulation
Other_PLK_PLK1_PLK1_ST	P30260	CDC27	P53350	PLK1	T430	N424S	424	Missense	distal	-6	no	13.602	13.799	EPSD;PhosphoSitePlus	ICGC;COSMIC	10.919	Up-regulation
Other_PLK_PLK1_PLK1_ST	P30260	CDC27	P53350	PLK1	T430	I436V	436	Missense	distal	6	no	13.602	13.708	EPSD;PhosphoSitePlus	ICGC;COSMIC	10.919	Up-regulation
Other_PLK_PLK1_PLK1_ST	P30260	CDC27	P53350	PLK1	T430	S434Y	434	Missense	distal	4	no	13.602	13.359	EPSD;PhosphoSitePlus	ICGC;COSMIC	10.919	Down-regulation
Other_PLK_PLK1_PLK1_ST	P30260	CDC27	P53350	PLK1	T430	S426N	426	Missense	distal	-4	no	13.602	13.467	EPSD;PhosphoSitePlus	ICGC	10.919	Down-regulation
Other_PLK_PLK1_PLK1_ST	P30260	CDC27	P53350	PLK1	S434	S435F	435	Missense	proximal	1	no	9.797	12.845	EPSD;PhosphoSitePlus	ICGC;COSMIC	10.919	Gain
Other_PLK_PLK1_PLK1_ST	P30260	CDC27	P53350	PLK1	S435	S435F	435	Missense	central	0	yes	16.993	0.000	EPSD;PhosphoSitePlus	ICGC;COSMIC	10.919	Loss
Other_PLK_PLK1_PLK1_ST	P30260	CDC27	P53350	PLK1	S435	G440E	440	Missense	distal	5	no	16.993	16.518	EPSD;PhosphoSitePlus	ICGC;COSMIC	10.919	Down-regulation
Other_PLK_PLK1_PLK1_ST	P30260	CDC27	P53350	PLK1	S435	K441E	441	Missense	distal	6	no	16.993	17.062	EPSD;PhosphoSitePlus	ICGC	10.919	Up-regulation
Other_PLK_PLK1_PLK1_ST	P30260	CDC27	P53350	PLK1	S435	I429V	429	Missense	distal	-6	no	16.993	16.649	EPSD;PhosphoSitePlus	ICGC;COSMIC	10.919	Down-regulation
Other_PLK_PLK1_PLK1_ST	P30260	CDC27	P53350	PLK1	S435	I429M	429	Missense	distal	-6	no	16.993	16.806	EPSD;PhosphoSitePlus	ICGC;COSMIC	10.919	Down-regulation
Other_PLK_PLK1_PLK1_ST	P30260	CDC27	P53350	PLK1	S435	I436V	436	Missense	proximal	1	no	16.993	16.802	EPSD;PhosphoSitePlus	ICGC;COSMIC	10.919	Down-regulation
Other_PLK_PLK1_PLK1_ST	P30260	CDC27	P53350	PLK1	S435	S434Y	434	Missense	proximal	-1	no	16.993	17.328	EPSD;PhosphoSitePlus	ICGC;COSMIC	10.919	Up-regulation
Other_PLK_PLK1_PLK1_ST	Q6PGQ7	BORA	P53350	PLK1	S233	L232F	232	Missense	proximal	-1	no	13.521	13.441	EPSD	ICGC	10.919	Down-regulation
Other_PLK_PLK1_PLK1_ST	Q6PGQ7	BORA	P53350	PLK1	S252	S250Y	250	Missense	proximal	-2	no	11.263	12.374	EPSD	ICGC	10.919	Up-regulation
Other_PLK_PLK1_PLK1_ST	Q6PGQ7	BORA	P53350	PLK1	S252	G247V	247	Missense	distal	-5	no	11.263	11.076	EPSD	ICGC	10.919	Down-regulation
Other_PLK_PLK1_PLK1_ST	Q6PGQ7	BORA	P53350	PLK1	S252	S252N	252	Missense	central	0	yes	11.263	0.000	EPSD	ICGC	10.919	Loss
Other_PLK_PLK1_PLK1_ST	Q6PGQ7	BORA	P53350	PLK1	T501	M495I	495	Missense	distal	-6	no	12.470	12.658	EPSD;PhosphoSitePlus	ICGC	10.919	Up-regulation
Other_PLK_PLK1_PLK1_ST	Q96CV9	OPTN	P53350	PLK1	T20	S15I	15	Missense	distal	-5	no	13.940	14.308	EPSD	ICGC;COSMIC	10.919	Up-regulation
Other_PLK_PLK1_PLK1_ST	Q96CV9	OPTN	P53350	PLK1	T20	E18K	18	Missense	proximal	-2	no	13.940	11.063	EPSD	ICGC;COSMIC	10.919	Down-regulation
Other_PLK_PLK1_PLK1_ST	Q96CV9	OPTN	P53350	PLK1	T20	S17I	17	Missense	distal	-3	no	13.940	14.339	EPSD	ICGC	10.919	Up-regulation
Other_PLK_PLK1_PLK1_ST	Q96CV9	OPTN	P53350	PLK1	T20	G21R	21	Missense	proximal	1	no	13.940	11.839	EPSD	ICGC;COSMIC	10.919	Down-regulation
Other_PLK_PLK1_PLK1_ST	Q96CV9	OPTN	P53350	PLK1	S171	E175K	175	Missense	distal	4	no	13.110	12.737	EPSD	ICGC	10.919	Down-regulation
Other_PLK_PLK1_PLK1_ST	Q96CV9	OPTN	P53350	PLK1	S177	E175K	175	Missense	proximal	-2	no	17.537	14.659	PhosphoSitePlus	ICGC	10.919	Down-regulation
Other_PLK_PLK1_PLK1_ST	Q96CV9	OPTN	P53350	PLK1	S216	R215S	215	Missense	proximal	-1	no	9.997	10.933	EPSD	ICGC;COSMIC;GDSC;CCLE	10.919	Gain
Other_PLK_PLK1_PLK1_ST	Q96CV9	OPTN	P53350	PLK1	S234	E229D	229	Missense	distal	-5	no	11.744	12.086	EPSD	ICGC	10.919	Up-regulation
Other_PLK_PLK1_PLK1_ST	Q96CV9	OPTN	P53350	PLK1	S272	N270I	270	Missense	proximal	-2	no	11.062	9.088	EPSD	ICGC;COSMIC	10.919	Loss
Other_PLK_PLK1_PLK1_ST	Q96CV9	OPTN	P53350	PLK1	S272	R271L	271	Missense	proximal	-1	no	11.062	11.539	EPSD	ICGC;COSMIC	10.919	Up-regulation
Other_PLK_PLK1_PLK1_ST	Q96CV9	OPTN	P53350	PLK1	S513	R511S	511	Missense	proximal	-2	no	11.791	12.017	EPSD	ICGC;COSMIC	10.919	Up-regulation
Other_PLK_PLK1_PLK1_ST	Q96CV9	OPTN	P53350	PLK1	S513	R520C	520	Missense	distal	7	no	11.791	11.844	EPSD	ICGC	10.919	Up-regulation
Other_PLK_PLK1_PLK1_ST	Q96CV9	OPTN	P53350	PLK1	S528	A523V	523	Missense	distal	-5	no	12.087	12.014	EPSD	ICGC;COSMIC	10.919	Down-regulation
Other_PLK_PLK1_PLK1_ST	Q96CV9	OPTN	P53350	PLK1	S528	G522V	522	Missense	distal	-6	no	12.087	12.358	EPSD	ICGC	10.919	Up-regulation
Other_PLK_PLK1_PLK1_ST	Q96CV9	OPTN	P53350	PLK1	S528	D529Y	529	Missense	proximal	1	no	12.087	11.890	EPSD	ICGC;COSMIC	10.919	Down-regulation
Other_PLK_PLK1_PLK1_ST	Q96CV9	OPTN	P53350	PLK1	S528	L534I	534	Missense	distal	6	no	12.087	12.049	EPSD	ICGC;COSMIC	10.919	Down-regulation
Other_PLK_PLK1_PLK1_ST	Q9HAW4	CLSPN	P53350	PLK1	S65	T69I	69	Missense	distal	4	no	11.089	10.090	EPSD	ICGC	10.919	Loss
Other_PLK_PLK1_PLK1_ST	Q9HAW4	CLSPN	P53350	PLK1	T72	T69I	69	Missense	distal	-3	no	11.782	11.804	EPSD	ICGC	10.919	Up-regulation
Other_PLK_PLK1_PLK1_ST	Q9HAW4	CLSPN	P53350	PLK1	T106	T106A	106	Missense	central	0	yes	11.758	0.000	EPSD	ICGC;COSMIC	10.919	Loss
Other_PLK_PLK1_PLK1_ST	Q9HAW4	CLSPN	P53350	PLK1	S113	T106A	106	Missense	distal	-7	no	13.398	13.053	EPSD	ICGC;COSMIC	10.919	Down-regulation
Other_PLK_PLK1_PLK1_ST	Q9HAW4	CLSPN	P53350	PLK1	S113	M115I	115	Missense	proximal	2	no	13.398	13.822	EPSD	ICGC;COSMIC;CCLE	10.919	Up-regulation
Other_PLK_PLK1_PLK1_ST	Q9HAW4	CLSPN	P53350	PLK1	S205	V198E	198	Missense	distal	-7	no	10.852	11.088	EPSD	ICGC;COSMIC	10.919	Gain
Other_PLK_PLK1_PLK1_ST	Q9HAW4	CLSPN	P53350	PLK1	S232	L233F	233	Missense	proximal	1	no	11.930	13.011	EPSD	ICGC;COSMIC	10.919	Up-regulation
Other_PLK_PLK1_PLK1_ST	Q9HAW4	CLSPN	P53350	PLK1	S426	S425N	425	Missense	proximal	-1	no	15.174	15.034	EPSD	ICGC;COSMIC	10.919	Down-regulation
Other_PLK_PLK1_PLK1_ST	Q9HAW4	CLSPN	P53350	PLK1	S516	L510I	510	Missense	distal	-6	no	14.014	14.417	EPSD	ICGC	10.919	Up-regulation
Other_PLK_PLK1_PLK1_ST	Q9HAW4	CLSPN	P53350	PLK1	S718	S718Y	718	Missense	central	0	yes	11.339	0.000	EPSD	ICGC	10.919	Loss
Other_PLK_PLK1_PLK1_ST	Q9HAW4	CLSPN	P53350	PLK1	S720	S718Y	718	Missense	proximal	-2	no	10.018	11.128	EPSD	ICGC	10.919	Gain
Other_PLK_PLK1_PLK1_ST	Q9HAW4	CLSPN	P53350	PLK1	T724	S718Y	718	Missense	distal	-6	no	10.943	10.090	EPSD	ICGC	10.919	Loss
Other_PLK_PLK1_PLK1_ST	Q9HAW4	CLSPN	P53350	PLK1	S762	S764L	764	Missense	proximal	2	no	13.073	13.144	EPSD	ICGC;COSMIC	10.919	Up-regulation
Other_PLK_PLK1_PLK1_ST	Q9HAW4	CLSPN	P53350	PLK1	S762	S762L	762	Missense	central	0	yes	13.073	0.000	EPSD	ICGC;COSMIC	10.919	Loss
Other_PLK_PLK1_PLK1_ST	Q9HAW4	CLSPN	P53350	PLK1	S771	S764L	764	Missense	distal	-7	no	13.109	12.804	EPSD	ICGC;COSMIC	10.919	Down-regulation
Other_PLK_PLK1_PLK1_ST	Q9HAW4	CLSPN	P53350	PLK1	S771	H772N	772	Missense	proximal	1	no	13.109	13.616	EPSD	ICGC	10.919	Up-regulation
Other_PLK_PLK1_PLK1_ST	Q9HAW4	CLSPN	P53350	PLK1	S771	S775F	775	Missense	distal	4	no	13.109	12.295	EPSD	ICGC;COSMIC	10.919	Down-regulation
Other_PLK_PLK1_PLK1_ST	Q9HAW4	CLSPN	P53350	PLK1	S839	A845P	845	Missense	distal	6	no	12.769	12.630	EPSD	ICGC;COSMIC	10.919	Down-regulation
Other_PLK_PLK1_PLK1_ST	Q9HAW4	CLSPN	P53350	PLK1	S954	S954I	954	Missense	central	0	yes	11.723	0.000	EPSD	ICGC	10.919	Loss
Other_PLK_PLK1_PLK1_ST	Q9HAW4	CLSPN	P53350	PLK1	S969	Q964H	964	Missense	distal	-5	no	13.432	13.369	EPSD	ICGC;COSMIC	10.919	Down-regulation
Other_PLK_PLK1_PLK1_ST	Q9HAW4	CLSPN	P53350	PLK1	S1018	E1014D	1014	Missense	distal	-4	no	12.314	12.130	EPSD	ICGC;COSMIC	10.919	Down-regulation
Other_PLK_PLK1_PLK1_ST	Q9HAW4	CLSPN	P53350	PLK1	S1020	E1014D	1014	Missense	distal	-6	no	11.043	10.840	EPSD	ICGC;COSMIC	10.919	Loss
Other_PLK_PLK1_PLK1_ST	Q13526	PIN1	P53350	PLK1	S65	R69W	69	Missense	distal	4	no	11.635	12.174	PhosphoSitePlus	ICGC;COSMIC	10.919	Up-regulation
Other_PLK_PLK1_PLK1_ST	Q13526	PIN1	P53350	PLK1	S138	G144W	144	Missense	distal	6	no	12.530	12.448	EPSD	ICGC;COSMIC	10.919	Down-regulation
Other_PLK_PLK1_PLK1_ST	Q13526	PIN1	P53350	PLK1	S138	G144E	144	Missense	distal	6	no	12.530	12.856	EPSD	ICGC;COSMIC	10.919	Up-regulation
Other_PLK_PLK1_PLK1_ST	Q13526	PIN1	P53350	PLK1	S138	G144V	144	Missense	distal	6	no	12.530	12.842	EPSD	ICGC;COSMIC	10.919	Up-regulation
Other_PLK_PLK1_PLK1_ST	Q13526	PIN1	P53350	PLK1	S147	G144W	144	Missense	distal	-3	no	11.576	10.854	EPSD	ICGC;COSMIC	10.919	Loss
Other_PLK_PLK1_PLK1_ST	Q13526	PIN1	P53350	PLK1	S147	G144E	144	Missense	distal	-3	no	11.576	10.634	EPSD	ICGC;COSMIC	10.919	Loss
Other_PLK_PLK1_PLK1_ST	Q13526	PIN1	P53350	PLK1	S147	G144V	144	Missense	distal	-3	no	11.576	10.927	EPSD	ICGC;COSMIC	10.919	Down-regulation
Other_PLK_PLK1_PLK1_ST	Q14674	ESPL1	P53350	PLK1	S325	A318S	318	Missense	distal	-7	no	13.012	13.365	EPSD	ICGC	10.919	Up-regulation
Other_PLK_PLK1_PLK1_ST	Q14674	ESPL1	P53350	PLK1	S810	S816P	816	Missense	distal	6	no	14.086	14.231	EPSD	ICGC;COSMIC;GDSC	10.919	Up-regulation
Other_PLK_PLK1_PLK1_ST	Q14674	ESPL1	P53350	PLK1	S810	K807E	807	Missense	distal	-3	no	14.086	13.546	EPSD	ICGC;COSMIC	10.919	Down-regulation
Other_PLK_PLK1_PLK1_ST	Q14674	ESPL1	P53350	PLK1	T1111	E1107Q	1107	Missense	distal	-4	no	11.985	11.716	EPSD	ICGC;COSMIC	10.919	Down-regulation
Other_PLK_PLK1_PLK1_ST	Q14674	ESPL1	P53350	PLK1	T1111	A1113S	1113	Missense	proximal	2	no	11.985	12.225	EPSD	ICGC	10.919	Up-regulation
Other_PLK_PLK1_PLK1_ST	Q14674	ESPL1	P53350	PLK1	T1111	E1115K	1115	Missense	distal	4	no	11.985	11.611	EPSD	ICGC	10.919	Down-regulation
Other_PLK_PLK1_PLK1_ST	Q14674	ESPL1	P53350	PLK1	S1122	E1115K	1115	Missense	distal	-7	no	10.922	10.618	EPSD	ICGC	10.919	Loss
Other_PLK_PLK1_PLK1_ST	Q14674	ESPL1	P53350	PLK1	S1399	D1403G	1403	Missense	distal	4	no	15.258	15.169	PhosphoSitePlus;EPSD	ICGC;COSMIC	10.919	Down-regulation
Other_PLK_PLK1_PLK1_ST	Q14674	ESPL1	P53350	PLK1	S1399	E1402D	1402	Missense	distal	3	no	15.258	15.323	PhosphoSitePlus;EPSD	ICGC	10.919	Up-regulation
Other_PLK_PLK1_PLK1_ST	Q14674	ESPL1	P53350	PLK1	S1513	G1510R	1510	Missense	distal	-3	no	12.865	12.924	EPSD	ICGC;COSMIC	10.919	Up-regulation
Other_PLK_PLK1_PLK1_ST	Q14674	ESPL1	P53350	PLK1	S1539	K1541Q	1541	Missense	proximal	2	no	10.998	11.356	EPSD	ICGC;COSMIC	10.919	Up-regulation
Other_PLK_PLK1_PLK1_ST	Q14674	ESPL1	P53350	PLK1	S1539	R1535S	1535	Missense	distal	-4	no	10.998	11.564	EPSD	ICGC	10.919	Up-regulation
Other_PLK_PLK1_PLK1_ST	Q14674	ESPL1	P53350	PLK1	S1539	S1539I	1539	Missense	central	0	yes	10.998	0.000	EPSD	ICGC	10.919	Loss
Other_PLK_PLK1_PLK1_ST	Q14674	ESPL1	P53350	PLK1	S1539	D1537Y	1537	Missense	proximal	-2	no	10.998	9.456	EPSD	ICGC	10.919	Loss
Other_PLK_PLK1_PLK1_ST	Q14674	ESPL1	P53350	PLK1	S1539	S1538F	1538	Missense	proximal	-1	no	10.998	10.459	EPSD	ICGC	10.919	Loss
Other_PLK_PLK1_PLK1_ST	Q9UJX3	ANAPC7	P53350	PLK1	S64	L70F	70	Missense	distal	6	no	10.971	10.355	EPSD;PhosphoSitePlus	ICGC;COSMIC	10.919	Loss
Other_PLK_PLK1_PLK1_ST	Q9UJX3	ANAPC7	P53350	PLK1	S64	F71V	71	Missense	distal	7	no	10.971	10.949	EPSD;PhosphoSitePlus	ICGC;COSMIC	10.919	Down-regulation
Other_PLK_PLK1_PLK1_ST	Q9UJX3	ANAPC7	P53350	PLK1	S64	P68H	68	Missense	distal	4	no	10.971	10.772	EPSD;PhosphoSitePlus	ICGC;COSMIC	10.919	Loss
Other_PLK_PLK1_PLK1_ST	Q9UJX3	ANAPC7	P53350	PLK1	S64	N66K	66	Missense	proximal	2	no	10.971	9.996	EPSD;PhosphoSitePlus	ICGC;COSMIC	10.919	Loss
Other_PLK_PLK1_PLK1_ST	Q9UJX3	ANAPC7	P53350	PLK1	S64	N67I	67	Missense	distal	3	no	10.971	10.955	EPSD;PhosphoSitePlus	ICGC;COSMIC	10.919	Down-regulation
Other_PLK_PLK1_PLK1_ST	Q9UJX3	ANAPC7	P53350	PLK1	S111	A109E	109	Missense	proximal	-2	no	9.197	11.375	EPSD	ICGC;COSMIC	10.919	Gain
Other_PLK_PLK1_PLK1_ST	Q9UJX3	ANAPC7	P53350	PLK1	S557	E556K	556	Missense	proximal	-1	no	12.170	11.599	EPSD	ICGC;COSMIC	10.919	Down-regulation
Other_PLK_PLK1_PLK1_ST	P47736	RAP1GAP	P53350	PLK1	S477	P481S	481	Missense	distal	4	no	11.280	11.601	EPSD	ICGC;COSMIC	10.919	Up-regulation
Other_PLK_PLK1_PLK1_ST	P47736	RAP1GAP	P53350	PLK1	T522	P516S	516	Missense	distal	-6	no	10.414	11.038	EPSD	ICGC;COSMIC	10.919	Gain
Other_PLK_PLK1_PLK1_ST	P47736	RAP1GAP	P53350	PLK1	S537	E535D	535	Missense	proximal	-2	no	12.170	12.564	EPSD	ICGC;COSMIC	10.919	Up-regulation
Other_PLK_PLK1_PLK1_ST	P47736	RAP1GAP	P53350	PLK1	S538	E535D	535	Missense	distal	-3	no	11.098	11.557	EPSD	ICGC;COSMIC	10.919	Up-regulation
Other_PLK_PLK1_PLK1_ST	Q15208	STK38	P53350	PLK1	S252	Y246H	246	Missense	distal	-6	no	12.466	13.331	EPSD	ICGC	10.919	Up-regulation
Other_PLK_PLK1_PLK1_ST	Q15208	STK38	P53350	PLK1	T258	Q260H	260	Missense	proximal	2	no	11.535	11.913	EPSD	ICGC;COSMIC	10.919	Up-regulation
Other_PLK_PLK1_PLK1_ST	Q15208	STK38	P53350	PLK1	T258	N261K	261	Missense	distal	3	no	11.535	11.463	EPSD	ICGC;COSMIC	10.919	Down-regulation
Other_PLK_PLK1_PLK1_ST	Q15208	STK38	P53350	PLK1	S281	A279D	279	Missense	proximal	-2	no	8.676	11.247	EPSD	ICGC	10.919	Gain
Other_PLK_PLK1_PLK1_ST	Q15208	STK38	P53350	PLK1	T407	D406H	406	Missense	proximal	-1	no	12.002	11.270	PhosphoSitePlus;EPSD	ICGC	10.919	Down-regulation
Other_PLK_PLK1_PLK1_ST	Q15208	STK38	P53350	PLK1	T407	F410L	410	Missense	distal	3	no	12.002	11.795	PhosphoSitePlus;EPSD	ICGC	10.919	Down-regulation
Other_PLK_PLK1_PLK1_ST	Q15208	STK38	P53350	PLK1	T407	E412D	412	Missense	distal	5	no	12.002	12.443	PhosphoSitePlus;EPSD	ICGC	10.919	Up-regulation
Other_PLK_PLK1_PLK1_ST	O75170	PPP6R2	P53350	PLK1	T261	V266I	266	Missense	distal	5	no	11.267	11.736	EPSD	ICGC;COSMIC;GDSC	10.919	Up-regulation
Other_PLK_PLK1_PLK1_ST	O75170	PPP6R2	P53350	PLK1	T261	R260W	260	Missense	proximal	-1	no	11.267	9.977	EPSD	ICGC;COSMIC	10.919	Loss
Other_PLK_PLK1_PLK1_ST	O75170	PPP6R2	P53350	PLK1	S289	D288N	288	Missense	proximal	-1	no	12.308	11.375	EPSD;PhosphoSitePlus	ICGC;COSMIC	10.919	Down-regulation
Other_PLK_PLK1_PLK1_ST	O75170	PPP6R2	P53350	PLK1	S289	E284D	284	Missense	distal	-5	no	12.308	12.649	EPSD;PhosphoSitePlus	ICGC	10.919	Up-regulation
Other_PLK_PLK1_PLK1_ST	O75170	PPP6R2	P53350	PLK1	S427	E429Q	429	Missense	proximal	2	no	11.505	11.694	EPSD	ICGC;COSMIC	10.919	Up-regulation
Other_PLK_PLK1_PLK1_ST	O75170	PPP6R2	P53350	PLK1	S822	A819S	819	Missense	distal	-3	no	11.006	10.483	EPSD	ICGC;COSMIC	10.919	Loss
Other_PLK_PLK1_PLK1_ST	O75170	PPP6R2	P53350	PLK1	S823	A819S	819	Missense	distal	-4	no	11.551	11.512	EPSD	ICGC;COSMIC	10.919	Down-regulation
Other_PLK_PLK1_PLK1_ST	O15392	BIRC5	P53350	PLK1	T21	K23N	23	Missense	proximal	2	no	10.551	11.526	EPSD;PhosphoSitePlus	ICGC;COSMIC;GDSC;CCLE	10.919	Gain
Other_PLK_PLK1_PLK1_ST	O14920	IKBKB	P53350	PLK1	S550	Q548L	548	Missense	proximal	-2	no	11.849	11.302	EPSD	ICGC;COSMIC	10.919	Down-regulation
Other_PLK_PLK1_PLK1_ST	O14920	IKBKB	P53350	PLK1	S550	G557A	557	Missense	distal	7	no	11.849	11.875	EPSD	ICGC;COSMIC	10.919	Up-regulation
Other_PLK_PLK1_PLK1_ST	P11388	TOP2A	P53350	PLK1	T282	D277E	277	Missense	distal	-5	no	12.520	12.178	EPSD	ICGC	10.919	Down-regulation
Other_PLK_PLK1_PLK1_ST	P11388	TOP2A	P53350	PLK1	T808	A801D	801	Missense	distal	-7	no	11.534	11.538	EPSD	ICGC	10.919	Up-regulation
Other_PLK_PLK1_PLK1_ST	P11388	TOP2A	P53350	PLK1	T825	D832V	832	Missense	distal	7	no	11.513	11.587	EPSD	ICGC	10.919	Up-regulation
Other_PLK_PLK1_PLK1_ST	P11388	TOP2A	P53350	PLK1	T825	H824Y	824	Missense	proximal	-1	no	11.513	11.788	EPSD	ICGC	10.919	Up-regulation
Other_PLK_PLK1_PLK1_ST	P11388	TOP2A	P53350	PLK1	T825	T825M	825	Missense	central	0	yes	11.513	0.000	EPSD	ICGC;COSMIC	10.919	Loss
Other_PLK_PLK1_PLK1_ST	P11388	TOP2A	P53350	PLK1	S1106	E1104K	1104	Missense	proximal	-2	no	14.821	11.944	EPSD	ICGC	10.919	Down-regulation
Other_PLK_PLK1_PLK1_ST	P11388	TOP2A	P53350	PLK1	S1106	E1109K	1109	Missense	distal	3	no	14.821	14.615	EPSD	ICGC;COSMIC	10.919	Down-regulation
Other_PLK_PLK1_PLK1_ST	P11388	TOP2A	P53350	PLK1	S1115	G1122E	1122	Missense	distal	7	no	13.258	13.237	EPSD	ICGC;COSMIC	10.919	Down-regulation
Other_PLK_PLK1_PLK1_ST	P11388	TOP2A	P53350	PLK1	S1115	E1109K	1109	Missense	distal	-6	no	13.258	12.685	EPSD	ICGC;COSMIC	10.919	Down-regulation
Other_PLK_PLK1_PLK1_ST	P11388	TOP2A	P53350	PLK1	S1117	P1123Q	1123	Missense	distal	6	no	12.973	12.810	EPSD	ICGC	10.919	Down-regulation
Other_PLK_PLK1_PLK1_ST	P11388	TOP2A	P53350	PLK1	S1117	G1122E	1122	Missense	distal	5	no	12.973	12.498	EPSD	ICGC;COSMIC	10.919	Down-regulation
Other_PLK_PLK1_PLK1_ST	P11388	TOP2A	P53350	PLK1	T1124	G1122E	1122	Missense	proximal	-2	no	8.456	11.384	EPSD	ICGC;COSMIC	10.919	Gain
Other_PLK_PLK1_PLK1_ST	P11388	TOP2A	P53350	PLK1	S1303	S1302I	1302	Missense	proximal	-1	no	11.790	11.807	EPSD	ICGC	10.919	Up-regulation
Other_PLK_PLK1_PLK1_ST	P11388	TOP2A	P53350	PLK1	S1306	P1311T	1311	Missense	distal	5	no	11.267	10.275	EPSD	ICGC	10.919	Loss
Other_PLK_PLK1_PLK1_ST	P11388	TOP2A	P53350	PLK1	S1306	S1302I	1302	Missense	distal	-4	no	11.267	11.301	EPSD	ICGC	10.919	Up-regulation
Other_PLK_PLK1_PLK1_ST	P11388	TOP2A	P53350	PLK1	T1343	P1350T	1350	Missense	distal	7	no	11.725	11.683	PhosphoSitePlus;EPSD	ICGC;COSMIC	10.919	Down-regulation
Other_PLK_PLK1_PLK1_ST	P11388	TOP2A	P53350	PLK1	S1354	P1355S	1355	Missense	proximal	1	no	12.687	11.565	EPSD	ICGC	10.919	Down-regulation
Other_PLK_PLK1_PLK1_ST	P11388	TOP2A	P53350	PLK1	S1354	P1350T	1350	Missense	distal	-4	no	12.687	12.447	EPSD	ICGC;COSMIC	10.919	Down-regulation
Other_PLK_PLK1_PLK1_ST	P11388	TOP2A	P53350	PLK1	T1403	E1404K	1404	Missense	proximal	1	no	11.487	11.037	EPSD	ICGC;COSMIC	10.919	Down-regulation
Other_PLK_PLK1_PLK1_ST	P11388	TOP2A	P53350	PLK1	T1403	P1408T	1408	Missense	distal	5	no	11.487	10.495	EPSD	ICGC	10.919	Loss
Other_PLK_PLK1_PLK1_ST	P11388	TOP2A	P53350	PLK1	T1406	P1408T	1408	Missense	proximal	2	no	10.630	11.466	EPSD	ICGC	10.919	Gain
Other_PLK_PLK1_PLK1_ST	P11388	TOP2A	P53350	PLK1	S1423	A1420E	1420	Missense	distal	-3	no	11.535	10.843	EPSD	ICGC;COSMIC	10.919	Loss
Other_PLK_PLK1_PLK1_ST	P11388	TOP2A	P53350	PLK1	S1469	R1464C	1464	Missense	distal	-5	no	10.934	10.268	EPSD	ICGC;COSMIC	10.919	Loss
Other_PLK_PLK1_PLK1_ST	P11388	TOP2A	P53350	PLK1	S1469	S1469P	1469	Missense	central	0	yes	10.934	0.000	EPSD	ICGC	10.919	Loss
Other_PLK_PLK1_PLK1_ST	P11388	TOP2A	P53350	PLK1	S1469	R1466T	1466	Missense	distal	-3	no	10.934	10.478	EPSD	ICGC;COSMIC	10.919	Loss
Other_PLK_PLK1_PLK1_ST	P11388	TOP2A	P53350	PLK1	S1469	D1473Y	1473	Missense	distal	4	no	10.934	10.688	EPSD	ICGC;COSMIC	10.919	Loss
Other_PLK_PLK1_PLK1_ST	P11388	TOP2A	P53350	PLK1	S1476	S1469P	1469	Missense	distal	-7	no	11.082	10.871	EPSD	ICGC	10.919	Loss
Other_PLK_PLK1_PLK1_ST	P11388	TOP2A	P53350	PLK1	S1476	D1473Y	1473	Missense	distal	-3	no	11.082	11.261	EPSD	ICGC;COSMIC	10.919	Up-regulation
Other_PLK_PLK1_PLK1_ST	P11388	TOP2A	P53350	PLK1	S1512	V1513I	1513	Missense	proximal	1	no	11.979	12.170	EPSD	ICGC	10.919	Up-regulation
Other_PLK_PLK1_PLK1_ST	P11388	TOP2A	P53350	PLK1	S1512	R1514G	1514	Missense	proximal	2	no	11.979	11.126	EPSD	ICGC;COSMIC	10.919	Down-regulation
Other_PLK_PLK1_PLK1_ST	Q9UBW7	ZMYM2	P53350	PLK1	S53	V54L	54	Missense	proximal	1	no	12.847	13.246	EPSD	ICGC;COSMIC	10.919	Up-regulation
Other_PLK_PLK1_PLK1_ST	Q9UBW7	ZMYM2	P53350	PLK1	S159	T157A	157	Missense	proximal	-2	no	13.793	14.412	EPSD	ICGC	10.919	Up-regulation
Other_PLK_PLK1_PLK1_ST	Q9UBW7	ZMYM2	P53350	PLK1	S159	S163I	163	Missense	distal	4	no	13.793	12.602	EPSD	ICGC	10.919	Down-regulation
Other_PLK_PLK1_PLK1_ST	Q9UBW7	ZMYM2	P53350	PLK1	S303	P299S	299	Missense	distal	-4	no	13.989	14.111	PhosphoSitePlus;EPSD	ICGC	10.919	Up-regulation
Other_PLK_PLK1_PLK1_ST	Q9UBW7	ZMYM2	P53350	PLK1	S305	P299S	299	Missense	distal	-6	no	10.895	11.518	EPSD;PhosphoSitePlus	ICGC	10.919	Gain
Other_PLK_PLK1_PLK1_ST	Q9UBW7	ZMYM2	P53350	PLK1	S439	R435H	435	Missense	distal	-4	no	11.028	11.330	EPSD	ICGC;COSMIC	10.919	Up-regulation
Other_PLK_PLK1_PLK1_ST	Q9UBW7	ZMYM2	P53350	PLK1	S522	V515F	515	Missense	distal	-7	no	12.281	12.121	EPSD	ICGC;COSMIC	10.919	Down-regulation
Other_PLK_PLK1_PLK1_ST	Q9UBW7	ZMYM2	P53350	PLK1	S591	N590D	590	Missense	proximal	-1	no	11.161	12.094	EPSD	ICGC;COSMIC	10.919	Up-regulation
Other_PLK_PLK1_PLK1_ST	Q9UBW7	ZMYM2	P53350	PLK1	S697	F703L	703	Missense	distal	6	no	10.600	11.216	EPSD	ICGC	10.919	Gain
Other_PLK_PLK1_PLK1_ST	Q9UBW7	ZMYM2	P53350	PLK1	S1056	A1050S	1050	Missense	distal	-6	no	12.321	12.357	EPSD	ICGC	10.919	Up-regulation
Other_PLK_PLK1_PLK1_ST	Q8NHV4	NEDD1	P53350	PLK1	T100	G96S	96	Missense	distal	-4	no	12.667	13.321	EPSD	ICGC;COSMIC	10.919	Up-regulation
Other_PLK_PLK1_PLK1_ST	Q8NHV4	NEDD1	P53350	PLK1	S171	R166Q	166	Missense	distal	-5	no	11.265	10.525	EPSD	ICGC	10.919	Loss
Other_PLK_PLK1_PLK1_ST	Q8NHV4	NEDD1	P53350	PLK1	S171	Y170H	170	Missense	proximal	-1	no	11.265	10.990	EPSD	ICGC;COSMIC	10.919	Down-regulation
Other_PLK_PLK1_PLK1_ST	Q8NHV4	NEDD1	P53350	PLK1	S176	Y170H	170	Missense	distal	-6	no	10.061	10.925	EPSD	ICGC;COSMIC	10.919	Gain
Other_PLK_PLK1_PLK1_ST	Q8NHV4	NEDD1	P53350	PLK1	T286	H290Y	290	Missense	distal	4	no	12.204	12.482	EPSD	ICGC;COSMIC	10.919	Up-regulation
Other_PLK_PLK1_PLK1_ST	Q8NHV4	NEDD1	P53350	PLK1	T286	K291E	291	Missense	distal	5	no	12.204	12.193	EPSD	ICGC;COSMIC	10.919	Down-regulation
Other_PLK_PLK1_PLK1_ST	Q8NHV4	NEDD1	P53350	PLK1	S325	R324L	324	Missense	proximal	-1	no	12.356	12.833	EPSD	ICGC;COSMIC	10.919	Up-regulation
Other_PLK_PLK1_PLK1_ST	Q8NHV4	NEDD1	P53350	PLK1	S325	R324Q	324	Missense	proximal	-1	no	12.356	12.960	EPSD	ICGC;COSMIC;CCLE	10.919	Up-regulation
Other_PLK_PLK1_PLK1_ST	Q8NHV4	NEDD1	P53350	PLK1	T382	T380R	380	Missense	proximal	-2	no	13.757	14.069	EPSD;PhosphoSitePlus	ICGC;COSMIC	10.919	Up-regulation
Other_PLK_PLK1_PLK1_ST	Q8NHV4	NEDD1	P53350	PLK1	T382	R376Q	376	Missense	distal	-6	no	13.757	14.204	EPSD;PhosphoSitePlus	ICGC;COSMIC	10.919	Up-regulation
Other_PLK_PLK1_PLK1_ST	Q8NHV4	NEDD1	P53350	PLK1	T382	E386K	386	Missense	distal	4	no	13.757	13.383	EPSD;PhosphoSitePlus	ICGC;COSMIC	10.919	Down-regulation
Other_PLK_PLK1_PLK1_ST	Q8NHV4	NEDD1	P53350	PLK1	S396	D400N	400	Missense	distal	4	no	11.101	10.862	EPSD	ICGC;COSMIC	10.919	Loss
Other_PLK_PLK1_PLK1_ST	Q8NHV4	NEDD1	P53350	PLK1	S396	N392K	392	Missense	distal	-4	no	11.101	10.843	EPSD	ICGC;COSMIC	10.919	Loss
Other_PLK_PLK1_PLK1_ST	Q8NHV4	NEDD1	P53350	PLK1	S396	D399Y	399	Missense	distal	3	no	11.101	10.675	EPSD	ICGC	10.919	Loss
Other_PLK_PLK1_PLK1_ST	Q8NHV4	NEDD1	P53350	PLK1	S396	G390E	390	Missense	distal	-6	no	11.101	11.766	EPSD	ICGC;COSMIC	10.919	Up-regulation
Other_PLK_PLK1_PLK1_ST	Q8NHV4	NEDD1	P53350	PLK1	S396	G402V	402	Missense	distal	6	no	11.101	11.413	EPSD	ICGC;COSMIC	10.919	Up-regulation
Other_PLK_PLK1_PLK1_ST	Q8NHV4	NEDD1	P53350	PLK1	S396	N392H	392	Missense	distal	-4	no	11.101	10.971	EPSD	ICGC;COSMIC	10.919	Down-regulation
Other_PLK_PLK1_PLK1_ST	Q8NHV4	NEDD1	P53350	PLK1	S396	G390V	390	Missense	distal	-6	no	11.101	11.373	EPSD	ICGC	10.919	Up-regulation
Other_PLK_PLK1_PLK1_ST	Q8NHV4	NEDD1	P53350	PLK1	S397	G390E	390	Missense	distal	-7	no	10.501	11.136	EPSD;PhosphoSitePlus	ICGC;COSMIC	10.919	Gain
Other_PLK_PLK1_PLK1_ST	Q8NHV4	NEDD1	P53350	PLK1	S426	S423I	423	Missense	distal	-3	no	13.421	13.820	EPSD;PhosphoSitePlus	ICGC	10.919	Up-regulation
Other_PLK_PLK1_PLK1_ST	Q8NHV4	NEDD1	P53350	PLK1	S496	G489R	489	Missense	distal	-7	no	12.656	12.856	EPSD	ICGC;COSMIC	10.919	Up-regulation
Other_PLK_PLK1_PLK1_ST	Q8NHV4	NEDD1	P53350	PLK1	S496	F497L	497	Missense	proximal	1	no	12.656	11.576	EPSD	ICGC;COSMIC	10.919	Down-regulation
Other_PLK_PLK1_PLK1_ST	Q8NHV4	NEDD1	P53350	PLK1	S506	A508T	508	Missense	proximal	2	no	11.704	11.303	EPSD	ICGC;COSMIC;GDSC	10.919	Down-regulation
Other_PLK_PLK1_PLK1_ST	Q8NHV4	NEDD1	P53350	PLK1	S506	E509A	509	Missense	distal	3	no	11.704	11.348	EPSD	ICGC;COSMIC	10.919	Down-regulation
Other_PLK_PLK1_PLK1_ST	Q8NHV4	NEDD1	P53350	PLK1	S525	S525A	525	Missense	central	0	yes	10.929	0.000	EPSD	ICGC;COSMIC	10.919	Loss
Other_PLK_PLK1_PLK1_ST	Q8NHV4	NEDD1	P53350	PLK1	S525	K530N	530	Missense	distal	5	no	10.929	10.606	EPSD	ICGC	10.919	Loss
Other_PLK_PLK1_PLK1_ST	Q8NHV4	NEDD1	P53350	PLK1	S525	K527T	527	Missense	proximal	2	no	10.929	11.049	EPSD	ICGC;COSMIC	10.919	Up-regulation
Other_PLK_PLK1_PLK1_ST	Q8NHV4	NEDD1	P53350	PLK1	S525	S525Y	525	Missense	central	0	yes	10.929	0.000	EPSD	ICGC;COSMIC	10.919	Loss
Other_PLK_PLK1_PLK1_ST	Q8NHV4	NEDD1	P53350	PLK1	S525	E532D	532	Missense	distal	7	no	10.929	10.925	EPSD	ICGC;COSMIC	10.919	Down-regulation
Other_PLK_PLK1_PLK1_ST	Q8NHV4	NEDD1	P53350	PLK1	S558	S557F	557	Missense	proximal	-1	no	11.286	10.747	EPSD	ICGC;COSMIC	10.919	Loss
Other_PLK_PLK1_PLK1_ST	Q8NHV4	NEDD1	P53350	PLK1	S558	A561S	561	Missense	distal	3	no	11.286	11.462	EPSD	ICGC	10.919	Up-regulation
Other_PLK_PLK1_PLK1_ST	Q8NHV4	NEDD1	P53350	PLK1	S558	P553Q	553	Missense	distal	-5	no	11.286	10.969	EPSD	ICGC;COSMIC	10.919	Down-regulation
Other_PLK_PLK1_PLK1_ST	Q8NHV4	NEDD1	P53350	PLK1	S558	G562V	562	Missense	distal	4	no	11.286	10.910	EPSD	ICGC;COSMIC	10.919	Loss
Other_PLK_PLK1_PLK1_ST	Q8NHV4	NEDD1	P53350	PLK1	S558	S557Y	557	Missense	proximal	-1	no	11.286	11.622	EPSD	ICGC;COSMIC	10.919	Up-regulation
Other_PLK_PLK1_PLK1_ST	Q8NHV4	NEDD1	P53350	PLK1	S566	G562V	562	Missense	distal	-4	no	10.563	11.116	EPSD	ICGC;COSMIC	10.919	Gain
Other_PLK_PLK1_PLK1_ST	Q8NHV4	NEDD1	P53350	PLK1	S574	S568L	568	Missense	distal	-6	no	11.859	11.525	EPSD	ICGC;COSMIC	10.919	Down-regulation
Other_PLK_PLK1_PLK1_ST	Q8NHV4	NEDD1	P53350	PLK1	S574	R579W	579	Missense	distal	5	no	11.859	11.601	EPSD	ICGC;COSMIC	10.919	Down-regulation
Other_PLK_PLK1_PLK1_ST	Q8NHV4	NEDD1	P53350	PLK1	S637	L632F	632	Missense	distal	-5	no	12.013	11.088	PhosphoSitePlus;EPSD	ICGC	10.919	Down-regulation
Other_PLK_PLK1_PLK1_ST	Q8NHV4	NEDD1	P53350	PLK1	S637	R635T	635	Missense	proximal	-2	no	12.013	11.700	PhosphoSitePlus;EPSD	ICGC;COSMIC	10.919	Down-regulation
Other_PLK_PLK1_PLK1_ST	Q8NHV4	NEDD1	P53350	PLK1	S637	E634G	634	Missense	distal	-3	no	12.013	12.954	PhosphoSitePlus;EPSD	ICGC	10.919	Up-regulation
Other_PLK_PLK1_PLK1_ST	Q13042	CDC16	P53350	PLK1	S112	D110E	110	Missense	proximal	-2	no	12.015	11.621	PhosphoSitePlus	ICGC	10.919	Down-regulation
Other_PLK_PLK1_PLK1_ST	Q13042	CDC16	P53350	PLK1	S118	M123I	123	Missense	distal	5	no	11.095	11.296	EPSD	ICGC	10.919	Up-regulation
Other_PLK_PLK1_PLK1_ST	Q13042	CDC16	P53350	PLK1	S124	M123I	123	Missense	proximal	-1	no	11.071	11.016	EPSD	ICGC	10.919	Down-regulation
Other_PLK_PLK1_PLK1_ST	Q13042	CDC16	P53350	PLK1	S124	K129T	129	Missense	distal	5	no	11.071	10.747	EPSD	ICGC	10.919	Loss
Other_PLK_PLK1_PLK1_ST	Q13042	CDC16	P53350	PLK1	S324	R320G	320	Missense	distal	-4	no	11.458	11.370	EPSD	ICGC;COSMIC	10.919	Down-regulation
Other_PLK_PLK1_PLK1_ST	Q13042	CDC16	P53350	PLK1	S595	S595F	595	Missense	central	0	yes	11.491	0.000	EPSD	ICGC;COSMIC	10.919	Loss
Other_PLK_PLK1_PLK1_ST	Q13042	CDC16	P53350	PLK1	T599	S595F	595	Missense	distal	-4	no	17.407	17.088	EPSD	ICGC;COSMIC	10.919	Down-regulation
Other_PLK_PLK1_PLK1_ST	Q13042	CDC16	P53350	PLK1	S607	M610L	610	Missense	distal	3	no	14.099	14.241	EPSD	ICGC;COSMIC	10.919	Up-regulation
Other_PLK_PLK1_PLK1_ST	Q13042	CDC16	P53350	PLK1	S614	M610L	610	Missense	distal	-4	no	14.760	14.843	EPSD	ICGC;COSMIC	10.919	Up-regulation
Other_PLK_PLK1_PLK1_ST	Q13042	CDC16	P53350	PLK1	S614	D617Y	617	Missense	distal	3	no	14.760	14.334	EPSD	ICGC;COSMIC	10.919	Down-regulation
Other_PLK_PLK1_PLK1_ST	Q13042	CDC16	P53350	PLK1	S616	M610L	610	Missense	distal	-6	no	11.096	10.880	EPSD	ICGC;COSMIC	10.919	Loss
Other_PLK_PLK1_PLK1_ST	Q13042	CDC16	P53350	PLK1	S616	D617Y	617	Missense	proximal	1	no	11.096	10.899	EPSD	ICGC;COSMIC	10.919	Loss
Other_PLK_PLK1_PLK1_ST	Q13042	CDC16	P53350	PLK1	S619	D617Y	617	Missense	proximal	-2	no	11.703	10.161	EPSD	ICGC;COSMIC	10.919	Loss
Other_PLK_PLK1_PLK1_ST	P18031	PTPN1	P53350	PLK1	S13	S15N	15	Missense	proximal	2	no	11.426	11.640	EPSD	ICGC	10.919	Up-regulation
Other_PLK_PLK1_PLK1_ST	P18031	PTPN1	P53350	PLK1	S50	R45S	45	Missense	distal	-5	no	15.413	14.729	EPSD	ICGC	10.919	Down-regulation
Other_PLK_PLK1_PLK1_ST	Q8N4N8	KIF2B	P53350	PLK1	T125	N123T	123	Missense	proximal	-2	no	11.675	9.727	PhosphoSitePlus;EPSD	ICGC;COSMIC	10.919	Loss
Other_PLK_PLK1_PLK1_ST	Q8N4N8	KIF2B	P53350	PLK1	T125	I119T	119	Missense	distal	-6	no	11.675	11.503	PhosphoSitePlus;EPSD	ICGC;COSMIC	10.919	Down-regulation
Other_PLK_PLK1_PLK1_ST	Q8N4N8	KIF2B	P53350	PLK1	S444	M439I	439	Missense	distal	-5	no	10.813	11.118	EPSD	ICGC;COSMIC	10.919	Gain
Other_PLK_PLK1_PLK1_ST	Q8N4N8	KIF2B	P53350	PLK1	S444	G450E	450	Missense	distal	6	no	10.813	11.139	EPSD	ICGC	10.919	Gain
Other_PLK_PLK1_PLK1_ST	Q8N4N8	KIF2B	P53350	PLK1	S474	E470K	470	Missense	distal	-4	no	12.257	11.874	EPSD	ICGC;COSMIC	10.919	Down-regulation
Other_PLK_PLK1_PLK1_ST	Q8N4N8	KIF2B	P53350	PLK1	S474	K473N	473	Missense	proximal	-1	no	12.257	12.691	EPSD	ICGC;COSMIC	10.919	Up-regulation
Other_PLK_PLK1_PLK1_ST	Q8N4N8	KIF2B	P53350	PLK1	S575	G570E	570	Missense	distal	-5	no	11.721	11.224	EPSD	ICGC;COSMIC	10.919	Down-regulation
Other_PLK_PLK1_PLK1_ST	Q8N4N8	KIF2B	P53350	PLK1	S575	S575F	575	Missense	central	0	yes	11.721	0.000	EPSD	ICGC	10.919	Loss
Other_PLK_PLK1_PLK1_ST	Q8N4N8	KIF2B	P53350	PLK1	T610	L604P	604	Missense	distal	-6	no	11.387	11.098	EPSD	ICGC;COSMIC	10.919	Down-regulation
Other_PLK_PLK1_PLK1_ST	Q8N4N8	KIF2B	P53350	PLK1	T610	G615E	615	Missense	distal	5	no	11.387	10.912	EPSD	ICGC	10.919	Loss
Other_PLK_PLK1_PLK1_ST	Q8N4N8	KIF2B	P53350	PLK1	T610	I611L	611	Missense	proximal	1	no	11.387	11.595	EPSD	ICGC	10.919	Up-regulation
Other_PLK_PLK1_PLK1_ST	Q8N4N8	KIF2B	P53350	PLK1	T610	G606E	606	Missense	distal	-4	no	11.387	12.031	EPSD	ICGC	10.919	Up-regulation
Other_PLK_PLK1_PLK1_ST	Q8N4N8	KIF2B	P53350	PLK1	S617	G615E	615	Missense	proximal	-2	no	9.592	12.520	EPSD	ICGC	10.919	Gain
Other_PLK_PLK1_PLK1_ST	P0DMV8	HSPA1A	P53350	PLK1	S544	M549T	549	Missense	distal	5	no	11.463	10.762	EPSD	ICGC;COSMIC	10.919	Loss
Other_PLK_PLK1_PLK1_ST	Q9Y5T5	USP16	P53350	PLK1	S16	P12Q	12	Missense	distal	-4	no	13.082	12.926	EPSD	ICGC;COSMIC	10.919	Down-regulation
Other_PLK_PLK1_PLK1_ST	Q9Y5T5	USP16	P53350	PLK1	S17	C24S	24	Missense	distal	7	no	14.836	14.767	EPSD	ICGC	10.919	Down-regulation
Other_PLK_PLK1_PLK1_ST	Q9Y5T5	USP16	P53350	PLK1	S17	P12Q	12	Missense	distal	-5	no	14.836	14.518	EPSD	ICGC;COSMIC	10.919	Down-regulation
Other_PLK_PLK1_PLK1_ST	Q9Y5T5	USP16	P53350	PLK1	T19	P12Q	12	Missense	distal	-7	no	10.916	11.030	EPSD	ICGC;COSMIC	10.919	Gain
Other_PLK_PLK1_PLK1_ST	O14641	DVL2	P53350	PLK1	T39	T39N	39	Missense	central	0	yes	12.315	0.000	EPSD	ICGC	10.919	Loss
Other_PLK_PLK1_PLK1_ST	O14641	DVL2	P53350	PLK1	T39	R37S	37	Missense	proximal	-2	no	12.315	12.541	EPSD	ICGC	10.919	Up-regulation
Other_PLK_PLK1_PLK1_ST	O14641	DVL2	P53350	PLK1	T39	V46F	46	Missense	distal	7	no	12.315	12.336	EPSD	ICGC	10.919	Up-regulation
Other_PLK_PLK1_PLK1_ST	O14641	DVL2	P53350	PLK1	T39	R37H	37	Missense	proximal	-2	no	12.315	12.006	EPSD	ICGC;COSMIC	10.919	Down-regulation
Other_PLK_PLK1_PLK1_ST	O14641	DVL2	P53350	PLK1	S135	P134L	134	Missense	proximal	-1	no	10.338	11.052	EPSD	ICGC;COSMIC	10.919	Gain
Other_PLK_PLK1_PLK1_ST	O14641	DVL2	P53350	PLK1	T250	V256I	256	Missense	distal	6	no	12.068	11.961	EPSD	ICGC;COSMIC	10.919	Down-regulation
Other_PLK_PLK1_PLK1_ST	O14641	DVL2	P53350	PLK1	S252	V256I	256	Missense	distal	4	no	13.628	12.898	EPSD	ICGC;COSMIC	10.919	Down-regulation
Other_PLK_PLK1_PLK1_ST	O14641	DVL2	P53350	PLK1	S298	G292R	292	Missense	distal	-6	no	11.590	11.689	EPSD	ICGC	10.919	Up-regulation
Other_PLK_PLK1_PLK1_ST	O14641	DVL2	P53350	PLK1	S398	P394Q	394	Missense	distal	-4	no	11.555	11.399	EPSD	ICGC	10.919	Down-regulation
Other_PLK_PLK1_PLK1_ST	O14641	DVL2	P53350	PLK1	S398	M399V	399	Missense	proximal	1	no	11.555	10.399	EPSD	ICGC	10.919	Loss
Other_PLK_PLK1_PLK1_ST	O14641	DVL2	P53350	PLK1	S480	R473Q	473	Missense	distal	-7	no	10.672	11.073	EPSD	ICGC;COSMIC	10.919	Gain
Other_PLK_PLK1_PLK1_ST	O14641	DVL2	P53350	PLK1	S480	A479D	479	Missense	proximal	-1	no	10.672	11.932	EPSD	ICGC	10.919	Gain
Other_PLK_PLK1_PLK1_ST	O14641	DVL2	P53350	PLK1	S620	G619D	619	Missense	proximal	-1	no	8.851	11.441	EPSD	ICGC;COSMIC	10.919	Gain
Other_PLK_PLK1_PLK1_ST	O14641	DVL2	P53350	PLK1	S638	P645R	645	Missense	distal	7	no	12.252	12.241	EPSD	ICGC;COSMIC	10.919	Down-regulation
Other_PLK_PLK1_PLK1_ST	O14641	DVL2	P53350	PLK1	T715	G708S	708	Missense	distal	-7	no	10.244	10.940	EPSD	ICGC	10.919	Gain
Other_PLK_PLK1_PLK1_ST	Q3KR16	PLEKHG6	P53350	PLK1	S204	V203L	203	Missense	proximal	-1	no	10.444	10.941	EPSD	ICGC	10.919	Gain
Other_PLK_PLK1_PLK1_ST	Q3KR16	PLEKHG6	P53350	PLK1	S204	V203M	203	Missense	proximal	-1	no	10.444	11.472	EPSD	ICGC;COSMIC	10.919	Gain
Other_PLK_PLK1_PLK1_ST	Q3KR16	PLEKHG6	P53350	PLK1	T574	D577N	577	Missense	distal	3	no	15.143	14.943	PhosphoSitePlus	ICGC;COSMIC	10.919	Down-regulation
Other_PLK_PLK1_PLK1_ST	Q3KR16	PLEKHG6	P53350	PLK1	S697	A701T	701	Missense	distal	4	no	11.074	11.081	EPSD	ICGC;COSMIC	10.919	Up-regulation
Other_PLK_PLK1_PLK1_ST	Q3KR16	PLEKHG6	P53350	PLK1	S697	D702G	702	Missense	distal	5	no	11.074	11.108	EPSD	ICGC	10.919	Up-regulation
Other_PLK_PLK1_PLK1_ST	Q3KR16	PLEKHG6	P53350	PLK1	S697	A704T	704	Missense	distal	7	no	11.074	11.034	EPSD	ICGC;COSMIC	10.919	Down-regulation
Other_PLK_PLK1_PLK1_ST	Q3KR16	PLEKHG6	P53350	PLK1	S697	A701P	701	Missense	distal	4	no	11.074	10.951	EPSD	ICGC;COSMIC	10.919	Down-regulation
Other_PLK_PLK1_PLK1_ST	Q9H2D6	TRIOBP	P53350	PLK1	S245	Q242H	242	Missense	distal	-3	no	11.639	11.642	EPSD	ICGC;COSMIC	10.919	Up-regulation
Other_PLK_PLK1_PLK1_ST	Q9H2D6	TRIOBP	P53350	PLK1	S294	S294F	294	Missense	central	0	yes	11.684	0.000	EPSD	ICGC	10.919	Loss
Other_PLK_PLK1_PLK1_ST	Q9H2D6	TRIOBP	P53350	PLK1	S300	S294F	294	Missense	distal	-6	no	11.192	10.675	EPSD	ICGC	10.919	Loss
Other_PLK_PLK1_PLK1_ST	Q9H2D6	TRIOBP	P53350	PLK1	S304	S310F	310	Missense	distal	6	no	12.189	11.613	EPSD	ICGC;COSMIC	10.919	Down-regulation
Other_PLK_PLK1_PLK1_ST	Q9H2D6	TRIOBP	P53350	PLK1	S324	A322V	322	Missense	proximal	-2	no	11.428	11.387	EPSD	ICGC	10.919	Down-regulation
Other_PLK_PLK1_PLK1_ST	Q9H2D6	TRIOBP	P53350	PLK1	S638	R631W	631	Missense	distal	-7	no	10.671	11.257	EPSD	ICGC;COSMIC	10.919	Gain
Other_PLK_PLK1_PLK1_ST	Q9H2D6	TRIOBP	P53350	PLK1	T714	T715I	715	Missense	proximal	1	no	9.856	11.023	EPSD	ICGC;COSMIC	10.919	Gain
Other_PLK_PLK1_PLK1_ST	Q9H2D6	TRIOBP	P53350	PLK1	S856	N863K	863	Missense	distal	7	no	14.205	14.201	EPSD	ICGC;COSMIC	10.919	Down-regulation
Other_PLK_PLK1_PLK1_ST	Q9H2D6	TRIOBP	P53350	PLK1	S1124	Q1128H	1128	Missense	distal	4	no	11.761	11.655	EPSD	ICGC;COSMIC	10.919	Down-regulation
Other_PLK_PLK1_PLK1_ST	Q9H2D6	TRIOBP	P53350	PLK1	S1133	Q1128H	1128	Missense	distal	-5	no	11.981	11.918	EPSD	ICGC;COSMIC	10.919	Down-regulation
Other_PLK_PLK1_PLK1_ST	Q9H2D6	TRIOBP	P53350	PLK1	S1691	G1685V	1685	Missense	distal	-6	no	10.857	11.129	EPSD	ICGC	10.919	Gain
Other_PLK_PLK1_PLK1_ST	Q9H2D6	TRIOBP	P53350	PLK1	T1843	C1842F	1842	Missense	proximal	-1	no	9.824	11.145	EPSD	ICGC	10.919	Gain
Other_PLK_PLK1_PLK1_ST	Q9H2D6	TRIOBP	P53350	PLK1	S1900	A1905T	1905	Missense	distal	5	no	12.527	11.355	EPSD	ICGC;COSMIC	10.919	Down-regulation
Other_PLK_PLK1_PLK1_ST	Q9H2D6	TRIOBP	P53350	PLK1	S1900	D1899Y	1899	Missense	proximal	-1	no	12.527	12.070	EPSD	ICGC	10.919	Down-regulation
Other_PLK_PLK1_PLK1_ST	Q9H2D6	TRIOBP	P53350	PLK1	S1900	A1905S	1905	Missense	distal	5	no	12.527	11.960	EPSD	ICGC;COSMIC	10.919	Down-regulation
Other_PLK_PLK1_PLK1_ST	Q9H2D6	TRIOBP	P53350	PLK1	S1949	L1948V	1948	Missense	proximal	-1	no	11.977	11.479	EPSD	ICGC	10.919	Down-regulation
Other_PLK_PLK1_PLK1_ST	Q9H2D6	TRIOBP	P53350	PLK1	S2175	S2175C	2175	Missense	central	0	yes	12.179	0.000	EPSD	ICGC;COSMIC	10.919	Loss
Other_PLK_PLK1_PLK1_ST	Q9H2D6	TRIOBP	P53350	PLK1	S2175	R2172Q	2172	Missense	distal	-3	no	12.179	11.505	EPSD	ICGC;COSMIC;GDSC	10.919	Down-regulation
Other_PLK_PLK1_PLK1_ST	Q9H2D6	TRIOBP	P53350	PLK1	T2229	H2228D	2228	Missense	proximal	-1	no	11.598	12.330	EPSD	ICGC	10.919	Up-regulation
Other_PLK_PLK1_PLK1_ST	Q9H2D6	TRIOBP	P53350	PLK1	T2229	R2231H	2231	Missense	proximal	2	no	11.598	12.300	EPSD	ICGC;GDSC;CCLE	10.919	Up-regulation
Other_PLK_PLK1_PLK1_ST	Q9H2D6	TRIOBP	P53350	PLK1	S2329	V2324I	2324	Missense	distal	-5	no	12.366	12.523	EPSD	ICGC;COSMIC	10.919	Up-regulation
Other_PLK_PLK1_PLK1_ST	Q9H2D6	TRIOBP	P53350	PLK1	S2329	L2328V	2328	Missense	proximal	-1	no	12.366	11.869	EPSD	ICGC;COSMIC	10.919	Down-regulation
Other_PLK_PLK1_PLK1_ST	Q00987	MDM2	P53350	PLK1	S188	S190C	190	Missense	proximal	2	no	12.705	11.732	EPSD	ICGC;COSMIC	10.919	Down-regulation
Other_PLK_PLK1_PLK1_ST	Q00987	MDM2	P53350	PLK1	S190	S190C	190	Missense	central	0	yes	12.206	0.000	EPSD	ICGC;COSMIC	10.919	Loss
Other_PLK_PLK1_PLK1_ST	Q00987	MDM2	P53350	PLK1	S192	L199F	199	Missense	distal	7	no	13.025	13.096	EPSD	ICGC	10.919	Up-regulation
Other_PLK_PLK1_PLK1_ST	Q00987	MDM2	P53350	PLK1	S192	S190C	190	Missense	proximal	-2	no	13.025	10.625	EPSD	ICGC;COSMIC	10.919	Loss
Other_PLK_PLK1_PLK1_ST	Q00987	MDM2	P53350	PLK1	S196	L199F	199	Missense	distal	3	no	13.657	13.864	EPSD	ICGC	10.919	Up-regulation
Other_PLK_PLK1_PLK1_ST	Q00987	MDM2	P53350	PLK1	S196	S190C	190	Missense	distal	-6	no	13.657	12.454	EPSD	ICGC;COSMIC	10.919	Down-regulation
Other_PLK_PLK1_PLK1_ST	Q00987	MDM2	P53350	PLK1	S260	E267K	267	Missense	distal	7	no	14.954	15.027	PhosphoSitePlus	ICGC;COSMIC	10.919	Up-regulation
Other_PLK_PLK1_PLK1_ST	Q00987	MDM2	P53350	PLK1	S290	E285D	285	Missense	distal	-5	no	12.326	12.668	EPSD	ICGC;COSMIC	10.919	Up-regulation
Other_PLK_PLK1_PLK1_ST	Q00987	MDM2	P53350	PLK1	S342	I341V	341	Missense	proximal	-1	no	11.992	11.018	EPSD	ICGC;COSMIC	10.919	Down-regulation
Other_PLK_PLK1_PLK1_ST	Q00987	MDM2	P53350	PLK1	S388	E390Q	390	Missense	proximal	2	no	10.949	11.138	EPSD	ICGC;COSMIC	10.919	Up-regulation
Other_PLK_PLK1_PLK1_ST	Q00987	MDM2	P53350	PLK1	S425	V426F	426	Missense	proximal	1	no	11.011	12.491	EPSD	ICGC	10.919	Up-regulation
Other_PLK_PLK1_PLK1_ST	Q00987	MDM2	P53350	PLK1	S429	V426F	426	Missense	distal	-3	no	12.323	11.570	EPSD	ICGC	10.919	Down-regulation
Other_PLK_PLK1_PLK1_ST	Q00839	HNRNPU	P53350	PLK1	S26	L20I	20	Missense	distal	-6	no	10.607	11.011	EPSD	ICGC;COSMIC	10.919	Gain
Other_PLK_PLK1_PLK1_ST	Q00839	HNRNPU	P53350	PLK1	T286	D285E	285	Missense	proximal	-1	no	13.810	13.013	EPSD	ICGC;COSMIC	10.919	Down-regulation
Other_PLK_PLK1_PLK1_ST	Q00839	HNRNPU	P53350	PLK1	T286	T286I	286	Missense	central	0	yes	13.810	0.000	EPSD	ICGC;COSMIC	10.919	Loss
Other_PLK_PLK1_PLK1_ST	Q00839	HNRNPU	P53350	PLK1	T286	F283L	283	Missense	distal	-3	no	13.810	15.213	EPSD	ICGC;GDSC;CCLE	10.919	Up-regulation
Other_PLK_PLK1_PLK1_ST	Q00839	HNRNPU	P53350	PLK1	T474	Q477K	477	Missense	distal	3	no	13.648	13.550	EPSD	ICGC	10.919	Down-regulation
Other_PLK_PLK1_PLK1_ST	Q00839	HNRNPU	P53350	PLK1	T474	P480T	480	Missense	distal	6	no	13.648	13.780	EPSD	ICGC	10.919	Up-regulation
Other_PLK_PLK1_PLK1_ST	Q00839	HNRNPU	P53350	PLK1	T474	P480L	480	Missense	distal	6	no	13.648	13.544	EPSD	ICGC	10.919	Down-regulation
Other_PLK_PLK1_PLK1_ST	Q00839	HNRNPU	P53350	PLK1	T474	P480H	480	Missense	distal	6	no	13.648	12.981	EPSD	ICGC;COSMIC	10.919	Down-regulation
Other_PLK_PLK1_PLK1_ST	Q9NS56	TOPORS	P53350	PLK1	S65	A61V	61	Missense	distal	-4	no	11.259	11.119	EPSD	ICGC;COSMIC	10.919	Down-regulation
Other_PLK_PLK1_PLK1_ST	Q9NS56	TOPORS	P53350	PLK1	S191	E187Q	187	Missense	distal	-4	no	12.463	12.194	EPSD	ICGC;COSMIC	10.919	Down-regulation
Other_PLK_PLK1_PLK1_ST	P35222	CTNNB1	P53350	PLK1	S250	L252H	252	Missense	proximal	2	no	11.759	11.663	EPSD	ICGC;COSMIC	10.919	Down-regulation
Other_PLK_PLK1_PLK1_ST	O94901	SUN1	P53350	PLK1	S75	V81A	81	Missense	distal	6	no	12.337	12.513	EPSD	ICGC	10.919	Up-regulation
Other_PLK_PLK1_PLK1_ST	O94901	SUN1	P53350	PLK1	S108	R109M	109	Missense	proximal	1	no	8.322	12.210	EPSD	ICGC	10.919	Gain
Other_PLK_PLK1_PLK1_ST	O94901	SUN1	P53350	PLK1	S123	H118Y	118	Missense	distal	-5	no	10.959	11.176	EPSD	ICGC;COSMIC	10.919	Up-regulation
Other_PLK_PLK1_PLK1_ST	O94901	SUN1	P53350	PLK1	S123	G120V	120	Missense	distal	-3	no	10.959	10.310	EPSD	ICGC;COSMIC	10.919	Loss
Other_PLK_PLK1_PLK1_ST	O94901	SUN1	P53350	PLK1	S138	R141H	141	Missense	distal	3	no	14.201	14.333	PhosphoSitePlus	ICGC;COSMIC	10.919	Up-regulation
Other_PLK_PLK1_PLK1_ST	O94901	SUN1	P53350	PLK1	S138	V134L	134	Missense	distal	-4	no	14.201	14.108	PhosphoSitePlus	ICGC	10.919	Down-regulation
Other_PLK_PLK1_PLK1_ST	O94901	SUN1	P53350	PLK1	S138	D136G	136	Missense	proximal	-2	no	14.201	10.879	PhosphoSitePlus	ICGC;COSMIC	10.919	Loss
Other_PLK_PLK1_PLK1_ST	O94901	SUN1	P53350	PLK1	T199	P202L	202	Missense	distal	3	no	11.150	10.982	EPSD	ICGC	10.919	Down-regulation
Other_PLK_PLK1_PLK1_ST	P06748	NPM1	P53350	PLK1	S4	M9I	9	Missense	distal	5	no	11.886	12.087	PhosphoSitePlus	ICGC	10.919	Up-regulation
Other_PLK_PLK1_PLK1_ST	P06748	NPM1	P53350	PLK1	S4	D3H	3	Missense	proximal	-1	no	11.886	11.154	PhosphoSitePlus	ICGC;COSMIC	10.919	Down-regulation
Other_PLK_PLK1_PLK1_ST	P06748	NPM1	P53350	PLK1	S10	M9I	9	Missense	proximal	-1	no	11.004	10.950	EPSD	ICGC	10.919	Down-regulation
Other_PLK_PLK1_PLK1_ST	P06748	NPM1	P53350	PLK1	S10	D3H	3	Missense	distal	-7	no	11.004	11.237	EPSD	ICGC;COSMIC	10.919	Up-regulation
Other_PLK_PLK1_PLK1_ST	P06748	NPM1	P53350	PLK1	S43	L42S	42	Missense	proximal	-1	no	10.805	11.265	EPSD	ICGC;COSMIC	10.919	Gain
Other_PLK_PLK1_PLK1_ST	P06748	NPM1	P53350	PLK1	S70	Y67D	67	Missense	distal	-3	no	11.260	11.081	EPSD	ICGC;COSMIC	10.919	Down-regulation
Other_PLK_PLK1_PLK1_ST	P06748	NPM1	P53350	PLK1	S70	E68K	68	Missense	proximal	-2	no	11.260	8.383	EPSD	ICGC;COSMIC	10.919	Loss
Other_PLK_PLK1_PLK1_ST	P06748	NPM1	P53350	PLK1	S70	M65L	65	Missense	distal	-5	no	11.260	11.860	EPSD	ICGC;GDSC;CCLE	10.919	Up-regulation
Other_PLK_PLK1_PLK1_ST	Q13158	FADD	P53350	PLK1	S18	V11L	11	Missense	distal	-7	no	11.156	11.148	EPSD	ICGC	10.919	Down-regulation
Other_PLK_PLK1_PLK1_ST	Q13158	FADD	P53350	PLK1	S18	S14I	14	Missense	distal	-4	no	11.156	11.190	EPSD	ICGC;COSMIC	10.919	Up-regulation
Other_PLK_PLK1_PLK1_ST	Q13158	FADD	P53350	PLK1	S47	F46L	46	Missense	proximal	-1	no	10.899	10.978	EPSD	ICGC;GDSC;CCLE	10.919	Gain
Other_PLK_PLK1_PLK1_ST	Q13158	FADD	P53350	PLK1	S69	R71L	71	Missense	proximal	2	no	11.094	11.894	EPSD	ICGC;COSMIC	10.919	Up-regulation
Other_PLK_PLK1_PLK1_ST	Q13158	FADD	P53350	PLK1	S69	R72L	72	Missense	distal	3	no	11.094	11.072	EPSD	ICGC;COSMIC	10.919	Down-regulation
Other_PLK_PLK1_PLK1_ST	Q13158	FADD	P53350	PLK1	S190	R184H	184	Missense	distal	-6	no	11.755	12.214	EPSD	ICGC	10.919	Up-regulation
Other_PLK_PLK1_PLK1_ST	Q13158	FADD	P53350	PLK1	S190	Q187H	187	Missense	distal	-3	no	11.755	11.758	EPSD	ICGC;COSMIC	10.919	Up-regulation
Other_PLK_PLK1_PLK1_ST	Q13158	FADD	P53350	PLK1	S190	S197T	197	Missense	distal	7	no	11.755	11.740	EPSD	ICGC	10.919	Down-regulation
Other_PLK_PLK1_PLK1_ST	Q13158	FADD	P53350	PLK1	S194	Q187H	187	Missense	distal	-7	no	13.059	13.038	PhosphoSitePlus	ICGC;COSMIC	10.919	Down-regulation
Other_PLK_PLK1_PLK1_ST	Q13158	FADD	P53350	PLK1	S194	S197T	197	Missense	distal	3	no	13.059	12.921	PhosphoSitePlus	ICGC	10.919	Down-regulation
Other_PLK_PLK1_PLK1_ST	Q13158	FADD	P53350	PLK1	S194	N199T	199	Missense	distal	5	no	13.059	13.057	PhosphoSitePlus	ICGC;COSMIC	10.919	Down-regulation
Other_PLK_PLK1_PLK1_ST	Q13158	FADD	P53350	PLK1	S197	T204A	204	Missense	distal	7	no	11.761	11.801	EPSD	ICGC;COSMIC	10.919	Up-regulation
Other_PLK_PLK1_PLK1_ST	Q13158	FADD	P53350	PLK1	S197	N199T	199	Missense	proximal	2	no	11.761	10.907	EPSD	ICGC;COSMIC	10.919	Loss
Other_PLK_PLK1_PLK1_ST	Q13158	FADD	P53350	PLK1	S203	T204A	204	Missense	proximal	1	no	12.239	11.776	EPSD	ICGC;COSMIC	10.919	Down-regulation
Other_PLK_PLK1_PLK1_ST	Q13158	FADD	P53350	PLK1	S203	S197T	197	Missense	distal	-6	no	12.239	12.136	EPSD	ICGC	10.919	Down-regulation
Other_PLK_PLK1_PLK1_ST	Q13158	FADD	P53350	PLK1	S203	N199T	199	Missense	distal	-4	no	12.239	12.011	EPSD	ICGC;COSMIC	10.919	Down-regulation
Other_PLK_PLK1_PLK1_ST	P38398	BRCA1	P53350	PLK1	S114	D120G	120	Missense	distal	6	no	12.949	12.474	EPSD	ICGC;COSMIC	10.919	Down-regulation
Other_PLK_PLK1_PLK1_ST	P38398	BRCA1	P53350	PLK1	S114	H117N	117	Missense	distal	3	no	12.949	12.988	EPSD	ICGC;COSMIC	10.919	Up-regulation
Other_PLK_PLK1_PLK1_ST	P38398	BRCA1	P53350	PLK1	S123	D120G	120	Missense	distal	-3	no	14.179	14.662	EPSD	ICGC;COSMIC	10.919	Up-regulation
Other_PLK_PLK1_PLK1_ST	P38398	BRCA1	P53350	PLK1	S123	H117N	117	Missense	distal	-6	no	14.179	13.971	EPSD	ICGC;COSMIC	10.919	Down-regulation
Other_PLK_PLK1_PLK1_ST	P38398	BRCA1	P53350	PLK1	S187	T190N	190	Missense	distal	3	no	11.737	11.920	EPSD	ICGC	10.919	Up-regulation
Other_PLK_PLK1_PLK1_ST	P38398	BRCA1	P53350	PLK1	T190	T195N	195	Missense	distal	5	no	11.651	11.652	EPSD	ICGC	10.919	Up-regulation
Other_PLK_PLK1_PLK1_ST	P38398	BRCA1	P53350	PLK1	T190	T190N	190	Missense	central	0	yes	11.651	0.000	EPSD	ICGC	10.919	Loss
Other_PLK_PLK1_PLK1_ST	P38398	BRCA1	P53350	PLK1	T208	G211K	211	Missense	distal	3	no	11.967	11.937	EPSD	ICGC	10.919	Down-regulation
Other_PLK_PLK1_PLK1_ST	P38398	BRCA1	P53350	PLK1	T208	R213S	213	Missense	distal	5	no	11.967	11.622	EPSD	ICGC;COSMIC	10.919	Down-regulation
Other_PLK_PLK1_PLK1_ST	P38398	BRCA1	P53350	PLK1	T208	P209H	209	Missense	proximal	1	no	11.967	11.078	EPSD	ICGC;COSMIC	10.919	Down-regulation
Other_PLK_PLK1_PLK1_ST	P38398	BRCA1	P53350	PLK1	S603	N609I	609	Missense	distal	6	no	12.032	11.982	EPSD	ICGC	10.919	Down-regulation
Other_PLK_PLK1_PLK1_ST	P38398	BRCA1	P53350	PLK1	S868	S868C	868	Missense	central	0	yes	12.088	0.000	EPSD	ICGC;COSMIC	10.919	Loss
Other_PLK_PLK1_PLK1_ST	P38398	BRCA1	P53350	PLK1	T1163	S1164F	1164	Missense	proximal	1	no	8.473	11.521	EPSD	ICGC;COSMIC	10.919	Gain
Other_PLK_PLK1_PLK1_ST	P38398	BRCA1	P53350	PLK1	S1164	E1167D	1167	Missense	distal	3	no	13.392	13.458	PhosphoSitePlus	ICGC;COSMIC	10.919	Up-regulation
Other_PLK_PLK1_PLK1_ST	P38398	BRCA1	P53350	PLK1	S1164	S1164F	1164	Missense	central	0	yes	13.392	0.000	PhosphoSitePlus	ICGC;COSMIC	10.919	Loss
Other_PLK_PLK1_PLK1_ST	P38398	BRCA1	P53350	PLK1	S1164	K1160N	1160	Missense	distal	-4	no	13.392	13.650	PhosphoSitePlus	ICGC;COSMIC	10.919	Up-regulation
Other_PLK_PLK1_PLK1_ST	P38398	BRCA1	P53350	PLK1	S1174	E1167D	1167	Missense	distal	-7	no	13.313	13.023	EPSD	ICGC;COSMIC	10.919	Down-regulation
Other_PLK_PLK1_PLK1_ST	P51587	BRCA2	P53350	PLK1	S158	R155K	155	Missense	distal	-3	no	12.741	12.280	EPSD	ICGC;COSMIC	10.919	Down-regulation
Other_PLK_PLK1_PLK1_ST	P51587	BRCA2	P53350	PLK1	S193	S197F	197	Missense	distal	4	no	15.882	15.068	EPSD;PhosphoSitePlus	ICGC;COSMIC	10.919	Down-regulation
Other_PLK_PLK1_PLK1_ST	P51587	BRCA2	P53350	PLK1	T203	S205I	205	Missense	proximal	2	no	12.549	12.970	EPSD;PhosphoSitePlus	ICGC	10.919	Up-regulation
Other_PLK_PLK1_PLK1_ST	P51587	BRCA2	P53350	PLK1	T203	S197F	197	Missense	distal	-6	no	12.549	12.031	EPSD;PhosphoSitePlus	ICGC;COSMIC	10.919	Down-regulation
Other_PLK_PLK1_PLK1_ST	P51587	BRCA2	P53350	PLK1	S273	G267E	267	Missense	distal	-6	no	11.890	12.555	EPSD	ICGC;COSMIC	10.919	Up-regulation
Other_PLK_PLK1_PLK1_ST	P51587	BRCA2	P53350	PLK1	S273	C279F	279	Missense	distal	6	no	11.890	12.246	EPSD	ICGC	10.919	Up-regulation
Other_PLK_PLK1_PLK1_ST	P51587	BRCA2	P53350	PLK1	S497	Q499H	499	Missense	proximal	2	no	11.358	11.736	EPSD	ICGC;COSMIC	10.919	Up-regulation
Other_PLK_PLK1_PLK1_ST	P51587	BRCA2	P53350	PLK1	S652	T656S	656	Missense	distal	4	no	12.192	12.385	EPSD	ICGC;COSMIC	10.919	Up-regulation
Other_PLK_PLK1_PLK1_ST	P51587	BRCA2	P53350	PLK1	T768	I770N	770	Missense	proximal	2	no	14.092	13.884	EPSD	ICGC;COSMIC	10.919	Down-regulation
Other_PLK_PLK1_PLK1_ST	P51587	BRCA2	P53350	PLK1	T768	N765H	765	Missense	distal	-3	no	14.092	14.062	EPSD	ICGC;COSMIC	10.919	Down-regulation
Other_PLK_PLK1_PLK1_ST	P51587	BRCA2	P53350	PLK1	S791	K793N	793	Missense	proximal	2	no	10.105	11.080	EPSD	ICGC	10.919	Gain
Other_PLK_PLK1_PLK1_ST	P51587	BRCA2	P53350	PLK1	T933	T939S	939	Missense	distal	6	no	11.018	10.742	EPSD	ICGC;COSMIC	10.919	Loss
Other_PLK_PLK1_PLK1_ST	P51587	BRCA2	P53350	PLK1	S976	D974G	974	Missense	proximal	-2	no	11.705	8.383	EPSD	ICGC;COSMIC	10.919	Loss
Other_PLK_PLK1_PLK1_ST	P51587	BRCA2	P53350	PLK1	T1141	S1134I	1134	Missense	distal	-7	no	11.419	10.957	EPSD	ICGC	10.919	Down-regulation
Other_PLK_PLK1_PLK1_ST	P51587	BRCA2	P53350	PLK1	T1141	N1147K	1147	Missense	distal	6	no	11.419	11.421	EPSD	ICGC;COSMIC	10.919	Up-regulation
Other_PLK_PLK1_PLK1_ST	P51587	BRCA2	P53350	PLK1	S1770	V1775A	1775	Missense	distal	5	no	11.341	12.079	EPSD	ICGC;COSMIC	10.919	Up-regulation
Other_PLK_PLK1_PLK1_ST	P51587	BRCA2	P53350	PLK1	S1786	D1781Y	1781	Missense	distal	-5	no	16.155	16.010	EPSD	ICGC	10.919	Down-regulation
Other_PLK_PLK1_PLK1_ST	P51587	BRCA2	P53350	PLK1	S2072	G2078V	2078	Missense	distal	6	no	12.906	13.218	EPSD	ICGC;COSMIC	10.919	Up-regulation
Other_PLK_PLK1_PLK1_ST	P51587	BRCA2	P53350	PLK1	S2072	S2072F	2072	Missense	central	0	yes	12.906	0.000	EPSD	ICGC;COSMIC	10.919	Loss
Other_PLK_PLK1_PLK1_ST	P51587	BRCA2	P53350	PLK1	T2681	R2678K	2678	Missense	distal	-3	no	11.492	11.031	EPSD	ICGC;COSMIC	10.919	Down-regulation
Other_PLK_PLK1_PLK1_ST	P51587	BRCA2	P53350	PLK1	T2681	E2677Q	2677	Missense	distal	-4	no	11.492	11.223	EPSD	ICGC;COSMIC	10.919	Down-regulation
Other_PLK_PLK1_PLK1_ST	P51587	BRCA2	P53350	PLK1	S2695	A2698E	2698	Missense	distal	3	no	10.982	11.338	EPSD	ICGC;COSMIC	10.919	Up-regulation
Other_PLK_PLK1_PLK1_ST	P51587	BRCA2	P53350	PLK1	S2695	A2698S	2698	Missense	distal	3	no	10.982	11.158	EPSD	ICGC	10.919	Up-regulation
Other_PLK_PLK1_PLK1_ST	P51587	BRCA2	P53350	PLK1	S2697	A2698E	2698	Missense	proximal	1	no	11.231	11.792	EPSD	ICGC;COSMIC	10.919	Up-regulation
Other_PLK_PLK1_PLK1_ST	P51587	BRCA2	P53350	PLK1	S2697	A2698S	2698	Missense	proximal	1	no	11.231	11.101	EPSD	ICGC	10.919	Down-regulation
Other_PLK_PLK1_PLK1_ST	P51587	BRCA2	P53350	PLK1	S2701	A2698E	2698	Missense	distal	-3	no	12.697	12.006	EPSD	ICGC;COSMIC	10.919	Down-regulation
Other_PLK_PLK1_PLK1_ST	P51587	BRCA2	P53350	PLK1	S2701	A2698S	2698	Missense	distal	-3	no	12.697	12.175	EPSD	ICGC	10.919	Down-regulation
Other_PLK_PLK1_PLK1_ST	P51587	BRCA2	P53350	PLK1	S2998	S2993L	2993	Missense	distal	-5	no	10.493	11.157	EPSD	ICGC;COSMIC	10.919	Gain
Other_PLK_PLK1_PLK1_ST	Q9UBB4	ATXN10	P53350	PLK1	S77	S76C	76	Missense	proximal	-1	no	12.314	10.453	EPSD;PhosphoSitePlus	ICGC	10.919	Loss
Other_PLK_PLK1_PLK1_ST	Q9UBB4	ATXN10	P53350	PLK1	S364	V357M	357	Missense	distal	-7	no	12.850	12.717	EPSD	ICGC;COSMIC	10.919	Down-regulation
Other_PLK_PLK1_PLK1_ST	Q9H0H5	RACGAP1	P53350	PLK1	S112	M108V	108	Missense	distal	-4	no	12.534	12.710	EPSD	ICGC;COSMIC	10.919	Up-regulation
Other_PLK_PLK1_PLK1_ST	Q9H0H5	RACGAP1	P53350	PLK1	S149	S151F	151	Missense	proximal	2	no	12.161	11.610	EPSD	ICGC	10.919	Down-regulation
Other_PLK_PLK1_PLK1_ST	Q9H0H5	RACGAP1	P53350	PLK1	S157	E163G	163	Missense	distal	6	no	16.092	15.766	EPSD;PhosphoSitePlus	ICGC;COSMIC	10.919	Down-regulation
Other_PLK_PLK1_PLK1_ST	Q9H0H5	RACGAP1	P53350	PLK1	S157	D159E	159	Missense	proximal	2	no	16.092	15.501	EPSD;PhosphoSitePlus	ICGC	10.919	Down-regulation
Other_PLK_PLK1_PLK1_ST	Q9H0H5	RACGAP1	P53350	PLK1	S157	S151F	151	Missense	distal	-6	no	16.092	15.574	EPSD;PhosphoSitePlus	ICGC	10.919	Down-regulation
Other_PLK_PLK1_PLK1_ST	Q9H0H5	RACGAP1	P53350	PLK1	S164	E163G	163	Missense	proximal	-1	no	15.296	13.502	EPSD;PhosphoSitePlus	ICGC;COSMIC	10.919	Down-regulation
Other_PLK_PLK1_PLK1_ST	Q9H0H5	RACGAP1	P53350	PLK1	S164	D159E	159	Missense	distal	-5	no	15.296	14.954	EPSD;PhosphoSitePlus	ICGC	10.919	Down-regulation
Other_PLK_PLK1_PLK1_ST	Q9H0H5	RACGAP1	P53350	PLK1	S170	K176R	176	Missense	distal	6	no	17.385	17.026	PhosphoSitePlus;EPSD	ICGC	10.919	Down-regulation
Other_PLK_PLK1_PLK1_ST	Q9H0H5	RACGAP1	P53350	PLK1	S170	E163G	163	Missense	distal	-7	no	17.385	16.750	PhosphoSitePlus;EPSD	ICGC;COSMIC	10.919	Down-regulation
Other_PLK_PLK1_PLK1_ST	Q9H0H5	RACGAP1	P53350	PLK1	S214	G211W	211	Missense	distal	-3	no	11.094	10.371	EPSD;PhosphoSitePlus	ICGC;COSMIC	10.919	Loss
Other_PLK_PLK1_PLK1_ST	Q9H0H5	RACGAP1	P53350	PLK1	S234	E231K	231	Missense	distal	-3	no	10.474	11.014	EPSD	ICGC;COSMIC	10.919	Gain
Other_PLK_PLK1_PLK1_ST	Q9H0H5	RACGAP1	P53350	PLK1	S259	T260N	260	Missense	proximal	1	no	12.148	12.296	EPSD	ICGC	10.919	Up-regulation
Other_PLK_PLK1_PLK1_ST	Q9H0H5	RACGAP1	P53350	PLK1	S259	L261M	261	Missense	proximal	2	no	12.148	12.074	EPSD	ICGC	10.919	Down-regulation
Other_PLK_PLK1_PLK1_ST	Q9H0H5	RACGAP1	P53350	PLK1	T260	T260N	260	Missense	central	0	yes	13.596	0.000	EPSD;PhosphoSitePlus	ICGC	10.919	Loss
Other_PLK_PLK1_PLK1_ST	Q9H0H5	RACGAP1	P53350	PLK1	T260	L261M	261	Missense	proximal	1	no	13.596	14.353	EPSD;PhosphoSitePlus	ICGC	10.919	Up-regulation
Other_PLK_PLK1_PLK1_ST	Q9H0H5	RACGAP1	P53350	PLK1	S559	A561T	561	Missense	proximal	2	no	11.296	10.895	EPSD	ICGC;COSMIC	10.919	Loss
Other_PLK_PLK1_PLK1_ST	Q9H0H5	RACGAP1	P53350	PLK1	S559	L553I	553	Missense	distal	-6	no	11.296	11.699	EPSD	ICGC;COSMIC	10.919	Up-regulation
Other_PLK_PLK1_PLK1_ST	Q9H0H5	RACGAP1	P53350	PLK1	S559	L553Q	553	Missense	distal	-6	no	11.296	11.630	EPSD	ICGC;COSMIC	10.919	Up-regulation
Other_PLK_PLK1_PLK1_ST	Q9H0H5	RACGAP1	P53350	PLK1	S573	P568S	568	Missense	distal	-5	no	11.287	11.024	EPSD	ICGC;COSMIC	10.919	Down-regulation
Other_PLK_PLK1_PLK1_ST	Q9H0H5	RACGAP1	P53350	PLK1	S593	R597T	597	Missense	distal	4	no	11.836	12.588	EPSD	ICGC;COSMIC	10.919	Up-regulation
Other_PLK_PLK1_PLK1_ST	Q9H0H5	RACGAP1	P53350	PLK1	T606	S613I	613	Missense	distal	7	no	11.098	11.130	EPSD	ICGC;COSMIC	10.919	Up-regulation
Other_PLK_PLK1_PLK1_ST	Q9H0H5	RACGAP1	P53350	PLK1	S613	S613I	613	Missense	central	0	yes	11.889	0.000	EPSD	ICGC;COSMIC	10.919	Loss
Other_PLK_PLK1_PLK1_ST	O95251	KAT7	P53350	PLK1	S18	D13Y	13	Missense	distal	-5	no	14.690	14.545	EPSD	ICGC	10.919	Down-regulation
Other_PLK_PLK1_PLK1_ST	O95251	KAT7	P53350	PLK1	S18	G14V	14	Missense	distal	-4	no	14.690	15.244	EPSD	ICGC	10.919	Up-regulation
Other_PLK_PLK1_PLK1_ST	O95251	KAT7	P53350	PLK1	S21	G14V	14	Missense	distal	-7	no	12.134	12.534	EPSD	ICGC	10.919	Up-regulation
Other_PLK_PLK1_PLK1_ST	O95251	KAT7	P53350	PLK1	S52	Q51E	51	Missense	proximal	-1	no	13.226	13.554	EPSD	ICGC;COSMIC	10.919	Up-regulation
Other_PLK_PLK1_PLK1_ST	O95251	KAT7	P53350	PLK1	S52	P58L	58	Missense	distal	6	no	13.226	13.121	EPSD	ICGC	10.919	Down-regulation
Other_PLK_PLK1_PLK1_ST	O95251	KAT7	P53350	PLK1	S52	V59I	59	Missense	distal	7	no	13.226	13.210	EPSD	ICGC;COSMIC	10.919	Down-regulation
Other_PLK_PLK1_PLK1_ST	O95251	KAT7	P53350	PLK1	S53	Q51E	51	Missense	proximal	-2	no	9.809	12.468	EPSD	ICGC;COSMIC	10.919	Gain
Other_PLK_PLK1_PLK1_ST	O95251	KAT7	P53350	PLK1	S57	Q51E	51	Missense	distal	-6	no	13.232	13.351	PhosphoSitePlus	ICGC;COSMIC	10.919	Up-regulation
Other_PLK_PLK1_PLK1_ST	O95251	KAT7	P53350	PLK1	S57	R60L	60	Missense	distal	3	no	13.232	13.209	PhosphoSitePlus	ICGC;COSMIC	10.919	Down-regulation
Other_PLK_PLK1_PLK1_ST	O95251	KAT7	P53350	PLK1	S57	P58L	58	Missense	proximal	1	no	13.232	14.077	PhosphoSitePlus	ICGC	10.919	Up-regulation
Other_PLK_PLK1_PLK1_ST	O95251	KAT7	P53350	PLK1	S57	V59I	59	Missense	proximal	2	no	13.232	13.449	PhosphoSitePlus	ICGC;COSMIC	10.919	Up-regulation
Other_PLK_PLK1_PLK1_ST	O95251	KAT7	P53350	PLK1	S111	E114A	114	Missense	distal	3	no	11.300	10.944	EPSD	ICGC	10.919	Down-regulation
Other_PLK_PLK1_PLK1_ST	O95251	KAT7	P53350	PLK1	S111	T118A	118	Missense	distal	7	no	11.300	11.340	EPSD	ICGC;GDSC;CCLE	10.919	Up-regulation
Other_PLK_PLK1_PLK1_ST	O95251	KAT7	P53350	PLK1	S111	R113S	113	Missense	proximal	2	no	11.300	12.028	EPSD	ICGC;COSMIC	10.919	Up-regulation
Other_PLK_PLK1_PLK1_ST	O95251	KAT7	P53350	PLK1	S124	D122G	122	Missense	proximal	-2	no	12.875	9.553	EPSD	ICGC;COSMIC	10.919	Loss
Other_PLK_PLK1_PLK1_ST	O95251	KAT7	P53350	PLK1	S124	T118A	118	Missense	distal	-6	no	12.875	12.943	EPSD	ICGC;GDSC;CCLE	10.919	Up-regulation
Other_PLK_PLK1_PLK1_ST	O95251	KAT7	P53350	PLK1	S144	D141N	141	Missense	distal	-3	no	11.413	11.313	EPSD	ICGC;COSMIC	10.919	Down-regulation
Other_PLK_PLK1_PLK1_ST	O95251	KAT7	P53350	PLK1	S144	V147L	147	Missense	distal	3	no	11.413	11.115	EPSD	ICGC	10.919	Down-regulation
Other_PLK_PLK1_PLK1_ST	O95251	KAT7	P53350	PLK1	S144	S148Y	148	Missense	distal	4	no	11.413	11.170	EPSD	ICGC;COSMIC	10.919	Down-regulation
Other_PLK_PLK1_PLK1_ST	O95251	KAT7	P53350	PLK1	S148	D141N	141	Missense	distal	-7	no	10.821	10.962	EPSD	ICGC;COSMIC	10.919	Gain
Other_PLK_PLK1_PLK1_ST	O95251	KAT7	P53350	PLK1	S148	V147L	147	Missense	proximal	-1	no	10.821	11.318	EPSD	ICGC	10.919	Gain
Other_PLK_PLK1_PLK1_ST	O95251	KAT7	P53350	PLK1	S152	V147L	147	Missense	distal	-5	no	12.663	13.116	EPSD	ICGC	10.919	Up-regulation
Other_PLK_PLK1_PLK1_ST	O95251	KAT7	P53350	PLK1	S152	S158A	158	Missense	distal	6	no	12.663	12.946	EPSD	ICGC	10.919	Up-regulation
Other_PLK_PLK1_PLK1_ST	O95251	KAT7	P53350	PLK1	S152	S148Y	148	Missense	distal	-4	no	12.663	11.976	EPSD	ICGC;COSMIC	10.919	Down-regulation
Other_PLK_PLK1_PLK1_ST	O95251	KAT7	P53350	PLK1	S158	S158A	158	Missense	central	0	yes	17.801	0.000	EPSD	ICGC	10.919	Loss
Other_PLK_PLK1_PLK1_ST	O95251	KAT7	P53350	PLK1	S205	G198E	198	Missense	distal	-7	no	10.742	11.377	EPSD	ICGC	10.919	Gain
Other_PLK_PLK1_PLK1_ST	Q13127	REST	P53350	PLK1	S85	G92R	92	Missense	distal	7	no	13.632	13.649	EPSD	ICGC	10.919	Up-regulation
Other_PLK_PLK1_PLK1_ST	Q13127	REST	P53350	PLK1	S96	G92R	92	Missense	distal	-4	no	11.172	11.259	EPSD	ICGC	10.919	Up-regulation
Other_PLK_PLK1_PLK1_ST	Q13127	REST	P53350	PLK1	S201	E208K	208	Missense	distal	7	no	13.019	13.092	EPSD	ICGC;COSMIC	10.919	Up-regulation
Other_PLK_PLK1_PLK1_ST	Q13127	REST	P53350	PLK1	S204	E208K	208	Missense	distal	4	no	13.943	13.570	EPSD	ICGC;COSMIC	10.919	Down-regulation
Other_PLK_PLK1_PLK1_ST	Q13127	REST	P53350	PLK1	S555	P559Q	559	Missense	distal	4	no	11.914	11.821	EPSD	ICGC;COSMIC	10.919	Down-regulation
Other_PLK_PLK1_PLK1_ST	Q13127	REST	P53350	PLK1	S782	Q789H	789	Missense	distal	7	no	11.384	11.340	EPSD	ICGC	10.919	Down-regulation
Other_PLK_PLK1_PLK1_ST	Q13127	REST	P53350	PLK1	S782	V777F	777	Missense	distal	-5	no	11.384	10.912	EPSD	ICGC	10.919	Loss
Other_PLK_PLK1_PLK1_ST	Q13127	REST	P53350	PLK1	S861	E858A	858	Missense	distal	-3	no	10.609	11.300	EPSD	ICGC;COSMIC	10.919	Gain
Other_PLK_PLK1_PLK1_ST	Q13127	REST	P53350	PLK1	S942	V944F	944	Missense	proximal	2	no	14.159	13.404	EPSD	ICGC	10.919	Down-regulation
Other_PLK_PLK1_PLK1_ST	Q13127	REST	P53350	PLK1	S1024	D1021Y	1021	Missense	distal	-3	no	12.526	12.705	EPSD	ICGC	10.919	Up-regulation
Other_PLK_PLK1_PLK1_ST	Q13127	REST	P53350	PLK1	S1030	A1035S	1035	Missense	distal	5	no	12.929	12.362	PhosphoSitePlus	ICGC	10.919	Down-regulation
Other_PLK_PLK1_PLK1_ST	P30622	CLIP1	P53350	PLK1	T139	P141S	141	Missense	proximal	2	no	10.244	11.721	EPSD	ICGC	10.919	Gain
Other_PLK_PLK1_PLK1_ST	P30622	CLIP1	P53350	PLK1	S147	S143F	143	Missense	distal	-4	no	11.257	10.939	EPSD	ICGC;COSMIC	10.919	Down-regulation
Other_PLK_PLK1_PLK1_ST	P30622	CLIP1	P53350	PLK1	S147	A142T	142	Missense	distal	-5	no	11.257	11.188	EPSD	ICGC;COSMIC	10.919	Down-regulation
Other_PLK_PLK1_PLK1_ST	P30622	CLIP1	P53350	PLK1	S147	A154D	154	Missense	distal	7	no	11.257	11.205	EPSD	ICGC	10.919	Down-regulation
Other_PLK_PLK1_PLK1_ST	P30622	CLIP1	P53350	PLK1	S147	T153K	153	Missense	distal	6	no	11.257	11.034	EPSD	ICGC	10.919	Down-regulation
Other_PLK_PLK1_PLK1_ST	P30622	CLIP1	P53350	PLK1	S147	P141S	141	Missense	distal	-6	no	11.257	11.880	EPSD	ICGC	10.919	Up-regulation
Other_PLK_PLK1_PLK1_ST	P30622	CLIP1	P53350	PLK1	S147	S147L	147	Missense	central	0	yes	11.257	0.000	EPSD	ICGC;COSMIC	10.919	Loss
Other_PLK_PLK1_PLK1_ST	P30622	CLIP1	P53350	PLK1	S155	A154D	154	Missense	proximal	-1	no	10.660	11.920	EPSD	ICGC	10.919	Gain
Other_PLK_PLK1_PLK1_ST	P30622	CLIP1	P53350	PLK1	S180	E178D	178	Missense	proximal	-2	no	10.736	11.130	EPSD	ICGC;COSMIC	10.919	Gain
Other_PLK_PLK1_PLK1_ST	P30622	CLIP1	P53350	PLK1	S195	S193N	193	Missense	proximal	-2	no	10.423	11.832	EPSD;PhosphoSitePlus	ICGC;COSMIC	10.919	Gain
Other_PLK_PLK1_PLK1_ST	P30622	CLIP1	P53350	PLK1	S200	K207N	207	Missense	distal	7	no	14.269	14.274	EPSD	ICGC;COSMIC	10.919	Up-regulation
Other_PLK_PLK1_PLK1_ST	P30622	CLIP1	P53350	PLK1	S200	S193N	193	Missense	distal	-7	no	14.269	14.059	EPSD	ICGC;COSMIC	10.919	Down-regulation
Other_PLK_PLK1_PLK1_ST	P30622	CLIP1	P53350	PLK1	S312	S314P	314	Missense	proximal	2	no	11.365	9.889	EPSD;PhosphoSitePlus	ICGC;COSMIC	10.919	Loss
Other_PLK_PLK1_PLK1_ST	P30622	CLIP1	P53350	PLK1	S383	G386A	386	Missense	distal	3	no	11.438	11.259	EPSD	ICGC;COSMIC	10.919	Down-regulation
Other_PLK_PLK1_PLK1_ST	P30622	CLIP1	P53350	PLK1	S383	V385M	385	Missense	proximal	2	no	11.438	11.232	EPSD	ICGC;COSMIC	10.919	Down-regulation
Other_PLK_PLK1_PLK1_ST	P30622	CLIP1	P53350	PLK1	S553	E557K	557	Missense	distal	4	no	13.493	13.120	EPSD	ICGC;COSMIC	10.919	Down-regulation
Other_PLK_PLK1_PLK1_ST	P30622	CLIP1	P53350	PLK1	S989	T983S	983	Missense	distal	-6	no	11.026	11.129	EPSD	ICGC;COSMIC	10.919	Up-regulation
Other_PLK_PLK1_PLK1_ST	P30622	CLIP1	P53350	PLK1	S1066	A1061D	1061	Missense	distal	-5	no	11.272	11.232	EPSD	ICGC;COSMIC	10.919	Down-regulation
Other_PLK_PLK1_PLK1_ST	Q76N32	CEP68	P53350	PLK1	S126	E129K	129	Missense	distal	3	no	11.067	10.860	EPSD	ICGC;COSMIC	10.919	Loss
Other_PLK_PLK1_PLK1_ST	Q76N32	CEP68	P53350	PLK1	S260	R266C	266	Missense	distal	6	no	12.703	12.077	EPSD	ICGC	10.919	Down-regulation
Other_PLK_PLK1_PLK1_ST	Q76N32	CEP68	P53350	PLK1	S332	G333W	333	Missense	proximal	1	no	10.729	11.331	PhosphoSitePlus	ICGC;COSMIC	10.919	Gain
Other_PLK_PLK1_PLK1_ST	Q76N32	CEP68	P53350	PLK1	S338	G333W	333	Missense	distal	-5	no	13.169	13.222	EPSD	ICGC;COSMIC	10.919	Up-regulation
Other_PLK_PLK1_PLK1_ST	Q76N32	CEP68	P53350	PLK1	S354	T351I	351	Missense	distal	-3	no	11.324	11.347	EPSD	ICGC;COSMIC	10.919	Up-regulation
Other_PLK_PLK1_PLK1_ST	Q76N32	CEP68	P53350	PLK1	S354	C357S	357	Missense	distal	3	no	11.324	11.388	EPSD	ICGC;COSMIC	10.919	Up-regulation
Other_PLK_PLK1_PLK1_ST	Q76N32	CEP68	P53350	PLK1	S354	N356K	356	Missense	proximal	2	no	11.324	10.349	EPSD	ICGC;COSMIC	10.919	Loss
Other_PLK_PLK1_PLK1_ST	Q76N32	CEP68	P53350	PLK1	S478	S478I	478	Missense	central	0	yes	13.046	0.000	EPSD	ICGC	10.919	Loss
Other_PLK_PLK1_PLK1_ST	Q76N32	CEP68	P53350	PLK1	S478	S472L	472	Missense	distal	-6	no	13.046	12.712	EPSD	ICGC;COSMIC	10.919	Down-regulation
Other_PLK_PLK1_PLK1_ST	Q76N32	CEP68	P53350	PLK1	S577	G581W	581	Missense	distal	4	no	11.352	11.032	EPSD	ICGC;COSMIC	10.919	Down-regulation
Other_PLK_PLK1_PLK1_ST	Q76N32	CEP68	P53350	PLK1	S577	S577N	577	Missense	central	0	yes	11.352	0.000	EPSD	ICGC;COSMIC	10.919	Loss
Other_PLK_PLK1_PLK1_ST	Q76N32	CEP68	P53350	PLK1	S577	G572C	572	Missense	distal	-5	no	11.352	10.972	EPSD	ICGC	10.919	Down-regulation
Other_PLK_PLK1_PLK1_ST	P42898	MTHFR	P53350	PLK1	S18	S23L	23	Missense	distal	5	no	11.711	11.364	EPSD	ICGC;COSMIC	10.919	Down-regulation
Other_PLK_PLK1_PLK1_ST	P42898	MTHFR	P53350	PLK1	S21	S23L	23	Missense	proximal	2	no	11.166	11.237	EPSD	ICGC;COSMIC	10.919	Up-regulation
Other_PLK_PLK1_PLK1_ST	P42898	MTHFR	P53350	PLK1	S26	S23L	23	Missense	distal	-3	no	12.009	12.783	EPSD	ICGC;COSMIC	10.919	Up-regulation
Other_PLK_PLK1_PLK1_ST	P42898	MTHFR	P53350	PLK1	S465	E470A	470	Missense	distal	5	no	13.975	14.834	EPSD	ICGC;COSMIC	10.919	Up-regulation
Other_PLK_PLK1_PLK1_ST	Q15435	PPP1R7	P53350	PLK1	S24	D29N	29	Missense	distal	5	no	12.419	11.666	EPSD;PhosphoSitePlus	ICGC;COSMIC	10.919	Down-regulation
Other_PLK_PLK1_PLK1_ST	Q15435	PPP1R7	P53350	PLK1	S27	D29N	29	Missense	proximal	2	no	12.421	12.635	EPSD;PhosphoSitePlus	ICGC;COSMIC	10.919	Up-regulation
Other_PLK_PLK1_PLK1_ST	Q15435	PPP1R7	P53350	PLK1	S44	A41S	41	Missense	distal	-3	no	12.279	11.756	PhosphoSitePlus;EPSD	ICGC	10.919	Down-regulation
Other_PLK_PLK1_PLK1_ST	Q15435	PPP1R7	P53350	PLK1	S44	S47I	47	Missense	distal	3	no	12.279	12.308	PhosphoSitePlus;EPSD	ICGC	10.919	Up-regulation
Other_PLK_PLK1_PLK1_ST	Q15435	PPP1R7	P53350	PLK1	S47	A41S	41	Missense	distal	-6	no	13.541	13.577	EPSD;PhosphoSitePlus	ICGC	10.919	Up-regulation
Other_PLK_PLK1_PLK1_ST	Q15435	PPP1R7	P53350	PLK1	S47	S47I	47	Missense	central	0	yes	13.541	0.000	EPSD;PhosphoSitePlus	ICGC	10.919	Loss
Other_PLK_PLK1_PLK1_ST	Q15435	PPP1R7	P53350	PLK1	S47	R54Q	54	Missense	distal	7	no	13.541	13.556	EPSD;PhosphoSitePlus	ICGC;COSMIC	10.919	Up-regulation
Other_PLK_PLK1_PLK1_ST	Q15468	STIL	P53350	PLK1	S395	G396D	396	Missense	proximal	1	no	13.721	13.718	EPSD	ICGC;COSMIC	10.919	Down-regulation
Other_PLK_PLK1_PLK1_ST	Q15468	STIL	P53350	PLK1	S395	H393Q	393	Missense	proximal	-2	no	13.721	13.854	EPSD	ICGC	10.919	Up-regulation
Other_PLK_PLK1_PLK1_ST	Q15468	STIL	P53350	PLK1	S395	P389Q	389	Missense	distal	-6	no	13.721	14.344	EPSD	ICGC	10.919	Up-regulation
Other_PLK_PLK1_PLK1_ST	Q15468	STIL	P53350	PLK1	S403	G396D	396	Missense	distal	-7	no	11.467	11.813	EPSD	ICGC;COSMIC	10.919	Up-regulation
Other_PLK_PLK1_PLK1_ST	Q15468	STIL	P53350	PLK1	S403	P406T	406	Missense	distal	3	no	11.467	11.308	EPSD	ICGC	10.919	Down-regulation
Other_PLK_PLK1_PLK1_ST	Q15468	STIL	P53350	PLK1	S403	P410L	410	Missense	distal	7	no	11.467	11.438	EPSD	ICGC	10.919	Down-regulation
Other_PLK_PLK1_PLK1_ST	Q15468	STIL	P53350	PLK1	S811	T818N	818	Missense	distal	7	no	12.160	12.230	EPSD	ICGC	10.919	Up-regulation
Other_PLK_PLK1_PLK1_ST	Q15468	STIL	P53350	PLK1	S811	D810E	810	Missense	proximal	-1	no	12.160	11.363	EPSD	ICGC;COSMIC	10.919	Down-regulation
Other_PLK_PLK1_PLK1_ST	Q9UJX5	ANAPC4	P53350	PLK1	T256	K254N	254	Missense	proximal	-2	no	9.245	11.274	EPSD	ICGC	10.919	Gain
Other_PLK_PLK1_PLK1_ST	Q9UJX5	ANAPC4	P53350	PLK1	S285	M281I	281	Missense	distal	-4	no	11.078	11.388	EPSD	ICGC	10.919	Up-regulation
Other_PLK_PLK1_PLK1_ST	Q9UJX5	ANAPC4	P53350	PLK1	S343	L347S	347	Missense	distal	4	no	10.387	10.999	EPSD	ICGC;COSMIC	10.919	Gain
Other_PLK_PLK1_PLK1_ST	Q9UJX5	ANAPC4	P53350	PLK1	S779	E774V	774	Missense	distal	-5	no	12.823	13.132	PhosphoSitePlus	ICGC	10.919	Up-regulation
Other_PLK_PLK1_PLK1_ST	Q92574	TSC1	P53350	PLK1	S115	Q109K	109	Missense	distal	-6	no	11.424	10.969	EPSD	ICGC	10.919	Down-regulation
Other_PLK_PLK1_PLK1_ST	Q92574	TSC1	P53350	PLK1	T267	P266A	266	Missense	proximal	-1	no	10.670	11.376	EPSD	ICGC;COSMIC	10.919	Gain
Other_PLK_PLK1_PLK1_ST	Q92574	TSC1	P53350	PLK1	S270	G274A	274	Missense	distal	4	no	12.078	11.965	EPSD	ICGC;COSMIC	10.919	Down-regulation
Other_PLK_PLK1_PLK1_ST	Q92574	TSC1	P53350	PLK1	S270	P266A	266	Missense	distal	-4	no	12.078	12.240	EPSD	ICGC;COSMIC	10.919	Up-regulation
Other_PLK_PLK1_PLK1_ST	Q92574	TSC1	P53350	PLK1	S278	G274A	274	Missense	distal	-4	no	10.318	11.011	EPSD	ICGC;COSMIC	10.919	Gain
Other_PLK_PLK1_PLK1_ST	Q92574	TSC1	P53350	PLK1	T293	S289L	289	Missense	distal	-4	no	11.905	11.712	EPSD	ICGC;COSMIC	10.919	Down-regulation
Other_PLK_PLK1_PLK1_ST	Q92574	TSC1	P53350	PLK1	T293	D299E	299	Missense	distal	6	no	11.905	11.756	EPSD	ICGC	10.919	Down-regulation
Other_PLK_PLK1_PLK1_ST	Q92574	TSC1	P53350	PLK1	T293	T293N	293	Missense	central	0	yes	11.905	0.000	EPSD	ICGC	10.919	Loss
Other_PLK_PLK1_PLK1_ST	Q92574	TSC1	P53350	PLK1	T293	H287N	287	Missense	distal	-6	no	11.905	11.697	EPSD	ICGC	10.919	Down-regulation
Other_PLK_PLK1_PLK1_ST	Q92574	TSC1	P53350	PLK1	S331	R336W	336	Missense	distal	5	no	11.231	10.973	EPSD	ICGC;COSMIC	10.919	Down-regulation
Other_PLK_PLK1_PLK1_ST	Q92574	TSC1	P53350	PLK1	S331	Q325K	325	Missense	distal	-6	no	11.231	10.777	EPSD	ICGC;COSMIC	10.919	Loss
Other_PLK_PLK1_PLK1_ST	Q92574	TSC1	P53350	PLK1	T335	R336W	336	Missense	proximal	1	no	9.188	11.891	EPSD	ICGC;COSMIC	10.919	Gain
Other_PLK_PLK1_PLK1_ST	Q92574	TSC1	P53350	PLK1	S374	A381S	381	Missense	distal	7	no	11.007	10.982	EPSD	ICGC;COSMIC	10.919	Down-regulation
Other_PLK_PLK1_PLK1_ST	Q92574	TSC1	P53350	PLK1	S487	E493Q	493	Missense	distal	6	no	11.981	11.841	EPSD	ICGC;COSMIC	10.919	Down-regulation
Other_PLK_PLK1_PLK1_ST	Q92574	TSC1	P53350	PLK1	S487	A492E	492	Missense	distal	5	no	11.981	11.123	EPSD	ICGC	10.919	Down-regulation
Other_PLK_PLK1_PLK1_ST	Q92574	TSC1	P53350	PLK1	S487	R484I	484	Missense	distal	-3	no	11.981	11.549	EPSD	ICGC;COSMIC	10.919	Down-regulation
Other_PLK_PLK1_PLK1_ST	Q92574	TSC1	P53350	PLK1	T490	E493Q	493	Missense	distal	3	no	11.290	11.182	EPSD	ICGC;COSMIC	10.919	Down-regulation
Other_PLK_PLK1_PLK1_ST	Q92574	TSC1	P53350	PLK1	T490	A492E	492	Missense	proximal	2	no	11.290	10.938	EPSD	ICGC	10.919	Down-regulation
Other_PLK_PLK1_PLK1_ST	Q92574	TSC1	P53350	PLK1	T490	R484I	484	Missense	distal	-6	no	11.290	11.807	EPSD	ICGC;COSMIC	10.919	Up-regulation
Other_PLK_PLK1_PLK1_ST	Q92574	TSC1	P53350	PLK1	T490	E495G	495	Missense	distal	5	no	11.290	11.765	EPSD	ICGC;COSMIC	10.919	Up-regulation
Other_PLK_PLK1_PLK1_ST	Q92574	TSC1	P53350	PLK1	S511	R517Q	517	Missense	distal	6	no	11.428	11.716	EPSD	ICGC;COSMIC	10.919	Up-regulation
Other_PLK_PLK1_PLK1_ST	Q92574	TSC1	P53350	PLK1	S579	P583H	583	Missense	distal	4	no	13.965	13.766	EPSD;PhosphoSitePlus	ICGC;COSMIC	10.919	Down-regulation
Other_PLK_PLK1_PLK1_ST	Q92574	TSC1	P53350	PLK1	S579	Q573H	573	Missense	distal	-6	no	13.965	13.977	EPSD;PhosphoSitePlus	ICGC;COSMIC	10.919	Up-regulation
Other_PLK_PLK1_PLK1_ST	Q92574	TSC1	P53350	PLK1	S1025	S1030C	1030	Missense	distal	5	no	10.841	10.970	EPSD	ICGC	10.919	Gain
Other_PLK_PLK1_PLK1_ST	Q92574	TSC1	P53350	PLK1	S1030	S1030C	1030	Missense	central	0	yes	13.134	0.000	EPSD	ICGC	10.919	Loss
Other_PLK_PLK1_PLK1_ST	Q92574	TSC1	P53350	PLK1	S1046	P1048T	1048	Missense	proximal	2	no	10.316	11.152	EPSD	ICGC;COSMIC	10.919	Gain
Other_PLK_PLK1_PLK1_ST	Q92574	TSC1	P53350	PLK1	S1086	G1089C	1089	Missense	distal	3	no	11.172	11.105	EPSD	ICGC;COSMIC	10.919	Down-regulation
Other_PLK_PLK1_PLK1_ST	Q92574	TSC1	P53350	PLK1	S1100	R1097H	1097	Missense	distal	-3	no	12.001	11.329	EPSD	ICGC;COSMIC	10.919	Down-regulation
Other_PLK_PLK1_PLK1_ST	Q92574	TSC1	P53350	PLK1	S1100	E1101K	1101	Missense	proximal	1	no	12.001	11.550	EPSD	ICGC;COSMIC	10.919	Down-regulation
Other_PLK_PLK1_PLK1_ST	O60566	BUB1B	P53350	PLK1	T40	R33S	33	Missense	distal	-7	no	10.689	11.186	EPSD	ICGC	10.919	Gain
Other_PLK_PLK1_PLK1_ST	O60566	BUB1B	P53350	PLK1	T54	R60Q	60	Missense	distal	6	no	11.353	11.641	EPSD	ICGC;COSMIC	10.919	Up-regulation
Other_PLK_PLK1_PLK1_ST	O60566	BUB1B	P53350	PLK1	T54	Q57H	57	Missense	distal	3	no	11.353	11.288	EPSD	ICGC	10.919	Down-regulation
Other_PLK_PLK1_PLK1_ST	O60566	BUB1B	P53350	PLK1	T54	N52K	52	Missense	proximal	-2	no	11.353	9.324	EPSD	ICGC;COSMIC	10.919	Loss
Other_PLK_PLK1_PLK1_ST	O60566	BUB1B	P53350	PLK1	S270	M266I	266	Missense	distal	-4	no	11.658	11.968	EPSD	ICGC	10.919	Up-regulation
Other_PLK_PLK1_PLK1_ST	O60566	BUB1B	P53350	PLK1	T471	G465C	465	Missense	distal	-6	no	12.126	11.469	EPSD	ICGC	10.919	Down-regulation
Other_PLK_PLK1_PLK1_ST	O60566	BUB1B	P53350	PLK1	T471	G465S	465	Missense	distal	-6	no	12.126	12.672	EPSD	ICGC	10.919	Up-regulation
Other_PLK_PLK1_PLK1_ST	O60566	BUB1B	P53350	PLK1	T471	D466Y	466	Missense	distal	-5	no	12.126	11.980	EPSD	ICGC	10.919	Down-regulation
Other_PLK_PLK1_PLK1_ST	O60566	BUB1B	P53350	PLK1	T471	G465D	465	Missense	distal	-6	no	12.126	12.589	EPSD	ICGC;COSMIC	10.919	Up-regulation
Other_PLK_PLK1_PLK1_ST	O60566	BUB1B	P53350	PLK1	T471	E469K	469	Missense	proximal	-2	no	12.126	9.249	EPSD	ICGC;COSMIC	10.919	Loss
Other_PLK_PLK1_PLK1_ST	O60566	BUB1B	P53350	PLK1	T792	E790D	790	Missense	proximal	-2	no	11.538	11.932	EPSD;PhosphoSitePlus	ICGC	10.919	Up-regulation
Other_PLK_PLK1_PLK1_ST	Q14790	CASP8	P53350	PLK1	S16	D18Y	18	Missense	proximal	2	no	12.066	11.700	EPSD	ICGC;COSMIC	10.919	Down-regulation
Other_PLK_PLK1_PLK1_ST	Q14790	CASP8	P53350	PLK1	S16	I10T	10	Missense	distal	-6	no	12.066	11.894	EPSD	ICGC;COSMIC	10.919	Down-regulation
Other_PLK_PLK1_PLK1_ST	Q14790	CASP8	P53350	PLK1	S16	G11E	11	Missense	distal	-5	no	12.066	11.570	EPSD	ICGC;COSMIC	10.919	Down-regulation
Other_PLK_PLK1_PLK1_ST	Q14790	CASP8	P53350	PLK1	S16	L22I	22	Missense	distal	6	no	12.066	12.028	EPSD	ICGC;COSMIC	10.919	Down-regulation
Other_PLK_PLK1_PLK1_ST	Q14790	CASP8	P53350	PLK1	S16	G11R	11	Missense	distal	-5	no	12.066	12.351	EPSD	ICGC;COSMIC	10.919	Up-regulation
Other_PLK_PLK1_PLK1_ST	Q14790	CASP8	P53350	PLK1	S16	L22F	22	Missense	distal	6	no	12.066	11.450	EPSD	ICGC;COSMIC	10.919	Down-regulation
Other_PLK_PLK1_PLK1_ST	Q14790	CASP8	P53350	PLK1	S16	D18V	18	Missense	proximal	2	no	12.066	12.271	EPSD	ICGC;COSMIC	10.919	Up-regulation
Other_PLK_PLK1_PLK1_ST	Q14790	CASP8	P53350	PLK1	S26	F24I	24	Missense	proximal	-2	no	11.439	12.433	EPSD	ICGC	10.919	Up-regulation
Other_PLK_PLK1_PLK1_ST	Q14790	CASP8	P53350	PLK1	S26	F24L	24	Missense	proximal	-2	no	11.439	12.049	EPSD	ICGC;COSMIC	10.919	Up-regulation
Other_PLK_PLK1_PLK1_ST	Q14790	CASP8	P53350	PLK1	S26	L22I	22	Missense	distal	-4	no	11.439	11.667	EPSD	ICGC;COSMIC	10.919	Up-regulation
Other_PLK_PLK1_PLK1_ST	Q14790	CASP8	P53350	PLK1	S26	L22F	22	Missense	distal	-4	no	11.439	11.315	EPSD	ICGC;COSMIC	10.919	Down-regulation
Other_PLK_PLK1_PLK1_ST	Q14790	CASP8	P53350	PLK1	S26	Y29D	29	Missense	distal	3	no	11.439	11.865	EPSD	ICGC;COSMIC	10.919	Up-regulation
Other_PLK_PLK1_PLK1_ST	Q14790	CASP8	P53350	PLK1	S26	D28G	28	Missense	proximal	2	no	11.439	9.860	EPSD	ICGC;COSMIC	10.919	Loss
Other_PLK_PLK1_PLK1_ST	Q14790	CASP8	P53350	PLK1	S26	L25P	25	Missense	proximal	-1	no	11.439	10.725	EPSD	ICGC;COSMIC	10.919	Loss
Other_PLK_PLK1_PLK1_ST	Q14790	CASP8	P53350	PLK1	S26	P31L	31	Missense	distal	5	no	11.439	10.706	EPSD	ICGC;COSMIC	10.919	Loss
Other_PLK_PLK1_PLK1_ST	Q14790	CASP8	P53350	PLK1	S26	L27M	27	Missense	proximal	1	no	11.439	12.196	EPSD	ICGC;COSMIC	10.919	Up-regulation
Other_PLK_PLK1_PLK1_ST	Q14790	CASP8	P53350	PLK1	S60	L62P	62	Missense	proximal	2	no	11.832	10.284	EPSD	ICGC;COSMIC	10.919	Loss
Other_PLK_PLK1_PLK1_ST	Q14790	CASP8	P53350	PLK1	S60	S57C	57	Missense	distal	-3	no	11.832	11.868	EPSD	ICGC;COSMIC	10.919	Up-regulation
Other_PLK_PLK1_PLK1_ST	Q14790	CASP8	P53350	PLK1	S60	F67L	67	Missense	distal	7	no	11.832	11.761	EPSD	ICGC;COSMIC	10.919	Down-regulation
Other_PLK_PLK1_PLK1_ST	Q14790	CASP8	P53350	PLK1	S60	N58S	58	Missense	proximal	-2	no	11.832	10.423	EPSD	ICGC;COSMIC	10.919	Loss
Other_PLK_PLK1_PLK1_ST	Q14790	CASP8	P53350	PLK1	S60	S60P	60	Missense	central	0	yes	11.832	0.000	EPSD	ICGC;COSMIC	10.919	Loss
Other_PLK_PLK1_PLK1_ST	Q14790	CASP8	P53350	PLK1	S60	E64V	64	Missense	distal	4	no	11.832	11.382	EPSD	ICGC;COSMIC	10.919	Down-regulation
Other_PLK_PLK1_PLK1_ST	Q14790	CASP8	P53350	PLK1	S113	S115L	115	Missense	proximal	2	no	11.119	11.191	EPSD	ICGC;COSMIC	10.919	Up-regulation
Other_PLK_PLK1_PLK1_ST	Q14790	CASP8	P53350	PLK1	S113	S109L	109	Missense	distal	-4	no	11.119	10.926	EPSD	ICGC;COSMIC;CCLE	10.919	Down-regulation
Other_PLK_PLK1_PLK1_ST	Q14790	CASP8	P53350	PLK1	S113	R118G	118	Missense	distal	5	no	11.119	10.957	EPSD	ICGC;COSMIC	10.919	Down-regulation
Other_PLK_PLK1_PLK1_ST	Q14790	CASP8	P53350	PLK1	S113	Y106D	106	Missense	distal	-7	no	11.119	11.381	EPSD	ICGC;COSMIC	10.919	Up-regulation
Other_PLK_PLK1_PLK1_ST	Q14790	CASP8	P53350	PLK1	S113	I108N	108	Missense	distal	-5	no	11.119	10.698	EPSD	ICGC;COSMIC	10.919	Loss
Other_PLK_PLK1_PLK1_ST	Q14790	CASP8	P53350	PLK1	S113	V112A	112	Missense	proximal	-1	no	11.119	11.609	EPSD	ICGC;CCLE	10.919	Up-regulation
Other_PLK_PLK1_PLK1_ST	Q14790	CASP8	P53350	PLK1	S113	S113R	113	Missense	central	0	yes	11.119	0.000	EPSD	ICGC;COSMIC	10.919	Loss
Other_PLK_PLK1_PLK1_ST	Q14790	CASP8	P53350	PLK1	S113	R118K	118	Missense	distal	5	no	11.119	10.494	EPSD	ICGC;COSMIC	10.919	Loss
Other_PLK_PLK1_PLK1_ST	Q6IBW4	NCAPH2	P53350	PLK1	T138	V142F	142	Missense	distal	4	no	12.911	12.559	EPSD	ICGC;COSMIC	10.919	Down-regulation
Other_PLK_PLK1_PLK1_ST	Q6IBW4	NCAPH2	P53350	PLK1	T183	V185I	185	Missense	proximal	2	no	10.764	10.982	EPSD	ICGC;COSMIC	10.919	Gain
Other_PLK_PLK1_PLK1_ST	Q6IBW4	NCAPH2	P53350	PLK1	S325	L326F	326	Missense	proximal	1	no	10.472	11.553	EPSD	ICGC;COSMIC	10.919	Gain
Other_PLK_PLK1_PLK1_ST	Q6IBW4	NCAPH2	P53350	PLK1	S464	V461M	461	Missense	distal	-3	no	10.805	10.933	EPSD	ICGC;COSMIC	10.919	Gain
Other_PLK_PLK1_PLK1_ST	Q6IBW4	NCAPH2	P53350	PLK1	T501	R494H	494	Missense	distal	-7	no	10.716	11.095	EPSD	ICGC;COSMIC	10.919	Gain
Other_PLK_PLK1_PLK1_ST	Q6IBW4	NCAPH2	P53350	PLK1	T501	W498R	498	Missense	distal	-3	no	10.716	11.497	EPSD	ICGC;COSMIC	10.919	Gain
Other_PLK_PLK1_PLK1_ST	Q6IBW4	NCAPH2	P53350	PLK1	T579	T586M	586	Missense	distal	7	no	12.589	12.672	EPSD	ICGC;COSMIC;CCLE	10.919	Up-regulation
Other_PLK_PLK1_PLK1_ST	Q6IBW4	NCAPH2	P53350	PLK1	T579	G572W	572	Missense	distal	-7	no	12.589	13.374	EPSD	ICGC	10.919	Up-regulation
Other_PLK_PLK1_PLK1_ST	P14635	CCNB1	P53350	PLK1	S35	P37H	37	Missense	proximal	2	no	9.858	11.309	EPSD	ICGC;COSMIC	10.919	Gain
Other_PLK_PLK1_PLK1_ST	P14635	CCNB1	P53350	PLK1	S126	S128I	128	Missense	proximal	2	no	11.063	11.484	EPSD;PhosphoSitePlus	ICGC	10.919	Up-regulation
Other_PLK_PLK1_PLK1_ST	P14635	CCNB1	P53350	PLK1	S126	A125S	125	Missense	proximal	-1	no	11.063	11.530	EPSD;PhosphoSitePlus	ICGC	10.919	Up-regulation
Other_PLK_PLK1_PLK1_ST	P14635	CCNB1	P53350	PLK1	S126	L121F	121	Missense	distal	-5	no	11.063	10.138	EPSD;PhosphoSitePlus	ICGC;COSMIC	10.919	Loss
Other_PLK_PLK1_PLK1_ST	P14635	CCNB1	P53350	PLK1	S128	S128I	128	Missense	central	0	yes	12.040	0.000	EPSD;PhosphoSitePlus	ICGC	10.919	Loss
Other_PLK_PLK1_PLK1_ST	P14635	CCNB1	P53350	PLK1	S128	A125S	125	Missense	distal	-3	no	12.040	11.518	EPSD;PhosphoSitePlus	ICGC	10.919	Down-regulation
Other_PLK_PLK1_PLK1_ST	P14635	CCNB1	P53350	PLK1	S128	L121F	121	Missense	distal	-7	no	12.040	11.888	EPSD;PhosphoSitePlus	ICGC;COSMIC	10.919	Down-regulation
Other_PLK_PLK1_PLK1_ST	P14635	CCNB1	P53350	PLK1	S133	S128I	128	Missense	distal	-5	no	12.250	12.618	PhosphoSitePlus;EPSD	ICGC	10.919	Up-regulation
Other_PLK_PLK1_PLK1_ST	P14635	CCNB1	P53350	PLK1	S370	P363R	363	Missense	distal	-7	no	13.928	13.642	EPSD	ICGC	10.919	Down-regulation
Other_PLK_PLK1_PLK1_ST	P14635	CCNB1	P53350	PLK1	S370	L369M	369	Missense	proximal	-1	no	13.928	14.459	EPSD	ICGC;COSMIC	10.919	Up-regulation
Other_PLK_PLK1_PLK1_ST	P14635	CCNB1	P53350	PLK1	S413	T414I	414	Missense	proximal	1	no	11.332	12.499	EPSD	ICGC;COSMIC	10.919	Up-regulation
Other_PLK_PLK1_PLK1_ST	Q08050	FOXM1	P53350	PLK1	S306	T299M	299	Missense	distal	-7	no	11.603	11.182	EPSD	ICGC;COSMIC	10.919	Down-regulation
Other_PLK_PLK1_PLK1_ST	Q08050	FOXM1	P53350	PLK1	S306	W308L	308	Missense	proximal	2	no	11.603	11.656	EPSD	ICGC;COSMIC	10.919	Up-regulation
Other_PLK_PLK1_PLK1_ST	Q08050	FOXM1	P53350	PLK1	T354	I355M	355	Missense	proximal	1	no	11.477	12.442	EPSD	ICGC;COSMIC	10.919	Up-regulation
Other_PLK_PLK1_PLK1_ST	Q08050	FOXM1	P53350	PLK1	T354	I355T	355	Missense	proximal	1	no	11.477	10.310	EPSD	ICGC;COSMIC	10.919	Loss
Other_PLK_PLK1_PLK1_ST	Q08050	FOXM1	P53350	PLK1	T354	L359I	359	Missense	distal	5	no	11.477	12.121	EPSD	ICGC;COSMIC	10.919	Up-regulation
Other_PLK_PLK1_PLK1_ST	Q08050	FOXM1	P53350	PLK1	T354	N352K	352	Missense	proximal	-2	no	11.477	9.448	EPSD	ICGC	10.919	Loss
Other_PLK_PLK1_PLK1_ST	Q08050	FOXM1	P53350	PLK1	T354	R351L	351	Missense	distal	-3	no	11.477	11.419	EPSD	ICGC;COSMIC	10.919	Down-regulation
Other_PLK_PLK1_PLK1_ST	Q08050	FOXM1	P53350	PLK1	T354	R350C	350	Missense	distal	-4	no	11.477	11.231	EPSD	ICGC;COSMIC	10.919	Down-regulation
Other_PLK_PLK1_PLK1_ST	Q08050	FOXM1	P53350	PLK1	T354	L361M	361	Missense	distal	7	no	11.477	11.547	EPSD	ICGC;COSMIC	10.919	Up-regulation
Other_PLK_PLK1_PLK1_ST	Q08050	FOXM1	P53350	PLK1	S376	R373W	373	Missense	distal	-3	no	12.742	11.960	EPSD	ICGC;COSMIC	10.919	Down-regulation
Other_PLK_PLK1_PLK1_ST	Q08050	FOXM1	P53350	PLK1	S376	Q382K	382	Missense	distal	6	no	12.742	12.813	EPSD	ICGC	10.919	Up-regulation
Other_PLK_PLK1_PLK1_ST	Q08050	FOXM1	P53350	PLK1	S506	P509T	509	Missense	distal	3	no	11.361	11.203	EPSD	ICGC;COSMIC	10.919	Down-regulation
Other_PLK_PLK1_PLK1_ST	Q08050	FOXM1	P53350	PLK1	S638	G634R	634	Missense	distal	-4	no	11.396	11.484	EPSD	ICGC	10.919	Up-regulation
Other_PLK_PLK1_PLK1_ST	Q02750	MAP2K1	P53350	PLK1	S218	G225C	225	Missense	distal	7	no	13.962	14.031	EPSD;PhosphoSitePlus	ICGC	10.919	Up-regulation
Other_PLK_PLK1_PLK1_ST	Q02750	MAP2K1	P53350	PLK1	S218	L215I	215	Missense	distal	-3	no	13.962	13.587	EPSD;PhosphoSitePlus	ICGC;COSMIC	10.919	Down-regulation
Other_PLK_PLK1_PLK1_ST	Q02750	MAP2K1	P53350	PLK1	S222	G225C	225	Missense	distal	3	no	14.742	14.675	PhosphoSitePlus;EPSD	ICGC	10.919	Down-regulation
Other_PLK_PLK1_PLK1_ST	Q02750	MAP2K1	P53350	PLK1	S222	L215I	215	Missense	distal	-7	no	14.742	14.585	PhosphoSitePlus;EPSD	ICGC;COSMIC	10.919	Down-regulation
Other_PLK_PLK1_PLK1_ST	Q99741	CDC6	P53350	PLK1	T37	A32S	32	Missense	distal	-5	no	12.301	12.017	PhosphoSitePlus	ICGC	10.919	Down-regulation
Other_PLK_PLK1_PLK1_ST	Q99741	CDC6	P53350	PLK1	T37	V39F	39	Missense	proximal	2	no	12.301	11.545	PhosphoSitePlus	ICGC	10.919	Down-regulation
Other_PLK_PLK1_PLK1_ST	Q9Y266	NUDC	P53350	PLK1	S231	E225A	225	Missense	distal	-6	no	11.497	11.342	EPSD	ICGC;COSMIC	10.919	Down-regulation
Other_PLK_PLK1_PLK1_ST	Q9Y266	NUDC	P53350	PLK1	S231	V228A	228	Missense	distal	-3	no	11.497	11.896	EPSD	ICGC;COSMIC	10.919	Up-regulation
Other_PLK_PLK1_PLK1_ST	Q9Y266	NUDC	P53350	PLK1	S232	V228A	228	Missense	distal	-4	no	10.915	11.055	EPSD	ICGC;COSMIC	10.919	Gain
Other_PLK_PLK1_PLK1_ST	Q9Y266	NUDC	P53350	PLK1	S285	Y292F	292	Missense	distal	7	no	11.476	11.490	EPSD	ICGC;COSMIC	10.919	Up-regulation
Other_PLK_PLK1_PLK1_ST	Q9Y2T1	AXIN2	P53350	PLK1	S16	R18C	18	Missense	proximal	2	no	11.048	10.803	EPSD	ICGC;COSMIC	10.919	Loss
Other_PLK_PLK1_PLK1_ST	Q9Y2T1	AXIN2	P53350	PLK1	S16	R23Q	23	Missense	distal	7	no	11.048	11.063	EPSD	ICGC;COSMIC	10.919	Up-regulation
Other_PLK_PLK1_PLK1_ST	Q9Y2T1	AXIN2	P53350	PLK1	S311	A306V	306	Missense	distal	-5	no	16.971	16.899	PhosphoSitePlus	ICGC;COSMIC	10.919	Down-regulation
Other_PLK_PLK1_PLK1_ST	Q9Y2T1	AXIN2	P53350	PLK1	S311	A306E	306	Missense	distal	-5	no	16.971	16.590	PhosphoSitePlus	ICGC	10.919	Down-regulation
Other_PLK_PLK1_PLK1_ST	Q9Y2T1	AXIN2	P53350	PLK1	S461	R465S	465	Missense	distal	4	no	10.878	11.822	EPSD	ICGC;COSMIC	10.919	Gain
Other_PLK_PLK1_PLK1_ST	Q9Y2T1	AXIN2	P53350	PLK1	S461	P462L	462	Missense	proximal	1	no	10.878	11.723	EPSD	ICGC;COSMIC	10.919	Gain
Other_PLK_PLK1_PLK1_ST	Q9Y2T1	AXIN2	P53350	PLK1	S461	R465C	465	Missense	distal	4	no	10.878	11.296	EPSD	ICGC;COSMIC	10.919	Gain
Other_PLK_PLK1_PLK1_ST	Q99640	PKMYT1	P53350	PLK1	S469	P476T	476	Missense	distal	7	no	13.246	13.204	EPSD	ICGC;COSMIC	10.919	Down-regulation
Other_PLK_PLK1_PLK1_ST	O60216	RAD21	P53350	PLK1	S40	V41L	41	Missense	proximal	1	no	12.100	12.499	EPSD	ICGC;COSMIC	10.919	Up-regulation
Other_PLK_PLK1_PLK1_ST	O60216	RAD21	P53350	PLK1	S40	E34Q	34	Missense	distal	-6	no	12.100	11.980	EPSD	ICGC;COSMIC	10.919	Down-regulation
Other_PLK_PLK1_PLK1_ST	O60216	RAD21	P53350	PLK1	S43	V41L	41	Missense	proximal	-2	no	10.970	9.982	EPSD	ICGC;COSMIC	10.919	Loss
Other_PLK_PLK1_PLK1_ST	O60216	RAD21	P53350	PLK1	S46	V41L	41	Missense	distal	-5	no	10.822	11.275	EPSD	ICGC;COSMIC	10.919	Gain
Other_PLK_PLK1_PLK1_ST	O60216	RAD21	P53350	PLK1	S134	Q131K	131	Missense	distal	-3	no	11.727	11.941	EPSD	ICGC;COSMIC	10.919	Up-regulation
Other_PLK_PLK1_PLK1_ST	O60216	RAD21	P53350	PLK1	S138	T144A	144	Missense	distal	6	no	11.704	11.711	EPSD	ICGC;COSMIC	10.919	Up-regulation
Other_PLK_PLK1_PLK1_ST	O60216	RAD21	P53350	PLK1	S138	E142Q	142	Missense	distal	4	no	11.704	11.300	EPSD	ICGC;COSMIC	10.919	Down-regulation
Other_PLK_PLK1_PLK1_ST	O60216	RAD21	P53350	PLK1	S138	Q131K	131	Missense	distal	-7	no	11.704	11.436	EPSD	ICGC;COSMIC	10.919	Down-regulation
Other_PLK_PLK1_PLK1_ST	O60216	RAD21	P53350	PLK1	T144	T144A	144	Missense	central	0	yes	15.810	0.000	EPSD	ICGC;COSMIC	10.919	Loss
Other_PLK_PLK1_PLK1_ST	O60216	RAD21	P53350	PLK1	T144	E142Q	142	Missense	proximal	-2	no	15.810	13.151	EPSD	ICGC;COSMIC	10.919	Down-regulation
Other_PLK_PLK1_PLK1_ST	O60216	RAD21	P53350	PLK1	S153	D159Y	159	Missense	distal	6	no	14.190	13.391	EPSD	ICGC	10.919	Down-regulation
Other_PLK_PLK1_PLK1_ST	O60216	RAD21	P53350	PLK1	S153	I154F	154	Missense	proximal	1	no	14.190	15.479	EPSD	ICGC	10.919	Up-regulation
Other_PLK_PLK1_PLK1_ST	O60216	RAD21	P53350	PLK1	S280	M287L	287	Missense	distal	7	no	10.971	10.900	EPSD	ICGC;COSMIC	10.919	Loss
Other_PLK_PLK1_PLK1_ST	O60216	RAD21	P53350	PLK1	S280	V284F	284	Missense	distal	4	no	10.971	10.619	EPSD	ICGC;COSMIC	10.919	Loss
Other_PLK_PLK1_PLK1_ST	O60216	RAD21	P53350	PLK1	S280	D279N	279	Missense	proximal	-1	no	10.971	10.038	EPSD	ICGC	10.919	Loss
Other_PLK_PLK1_PLK1_ST	O60216	RAD21	P53350	PLK1	T312	I311V	311	Missense	proximal	-1	no	11.659	10.685	EPSD	ICGC;COSMIC	10.919	Loss
Other_PLK_PLK1_PLK1_ST	O60216	RAD21	P53350	PLK1	T312	V313F	313	Missense	proximal	1	no	11.659	13.139	EPSD	ICGC;COSMIC	10.919	Up-regulation
Other_PLK_PLK1_PLK1_ST	O60216	RAD21	P53350	PLK1	S328	K335M	335	Missense	distal	7	no	12.730	12.748	EPSD	ICGC;COSMIC	10.919	Up-regulation
Other_PLK_PLK1_PLK1_ST	O60216	RAD21	P53350	PLK1	S328	S334R	334	Missense	distal	6	no	12.730	12.423	EPSD	ICGC	10.919	Down-regulation
Other_PLK_PLK1_PLK1_ST	O60216	RAD21	P53350	PLK1	S342	K335M	335	Missense	distal	-7	no	11.135	11.070	EPSD	ICGC;COSMIC	10.919	Down-regulation
Other_PLK_PLK1_PLK1_ST	O43379	WDR62	P53350	PLK1	S20	V25I	25	Missense	distal	5	no	11.263	11.732	EPSD	ICGC;COSMIC	10.919	Up-regulation
Other_PLK_PLK1_PLK1_ST	O43379	WDR62	P53350	PLK1	T55	A51T	51	Missense	distal	-4	no	12.675	12.273	EPSD	ICGC	10.919	Down-regulation
Other_PLK_PLK1_PLK1_ST	O43379	WDR62	P53350	PLK1	S513	G514V	514	Missense	proximal	1	no	13.057	13.687	EPSD	ICGC;COSMIC	10.919	Up-regulation
Other_PLK_PLK1_PLK1_ST	O43379	WDR62	P53350	PLK1	S513	H519N	519	Missense	distal	6	no	13.057	13.630	EPSD	ICGC;COSMIC	10.919	Up-regulation
Other_PLK_PLK1_PLK1_ST	O43379	WDR62	P53350	PLK1	S684	A689T	689	Missense	distal	5	no	11.175	10.004	EPSD	ICGC;COSMIC	10.919	Loss
Other_PLK_PLK1_PLK1_ST	O43379	WDR62	P53350	PLK1	T781	E788Q	788	Missense	distal	7	no	11.155	11.208	EPSD	ICGC;COSMIC	10.919	Up-regulation
Other_PLK_PLK1_PLK1_ST	O43379	WDR62	P53350	PLK1	S791	G795E	795	Missense	distal	4	no	13.599	13.673	EPSD	ICGC;COSMIC	10.919	Up-regulation
Other_PLK_PLK1_PLK1_ST	O43379	WDR62	P53350	PLK1	S791	E788Q	788	Missense	distal	-3	no	13.599	13.925	EPSD	ICGC;COSMIC	10.919	Up-regulation
Other_PLK_PLK1_PLK1_ST	O43379	WDR62	P53350	PLK1	S791	S793I	793	Missense	proximal	2	no	13.599	14.020	EPSD	ICGC	10.919	Up-regulation
Other_PLK_PLK1_PLK1_ST	O43379	WDR62	P53350	PLK1	T798	E799K	799	Missense	proximal	1	no	12.704	12.254	EPSD	ICGC;COSMIC	10.919	Down-regulation
Other_PLK_PLK1_PLK1_ST	O43379	WDR62	P53350	PLK1	T798	G795E	795	Missense	distal	-3	no	12.704	11.763	EPSD	ICGC;COSMIC	10.919	Down-regulation
Other_PLK_PLK1_PLK1_ST	O43379	WDR62	P53350	PLK1	T798	S793I	793	Missense	distal	-5	no	12.704	13.072	EPSD	ICGC	10.919	Up-regulation
Other_PLK_PLK1_PLK1_ST	O43379	WDR62	P53350	PLK1	S897	S893N	893	Missense	distal	-4	no	14.056	13.921	PhosphoSitePlus	ICGC;COSMIC	10.919	Down-regulation
Other_PLK_PLK1_PLK1_ST	O43379	WDR62	P53350	PLK1	S987	S980Y	980	Missense	distal	-7	no	12.627	12.015	EPSD	ICGC;COSMIC	10.919	Down-regulation
Other_PLK_PLK1_PLK1_ST	O43379	WDR62	P53350	PLK1	S987	P988Q	988	Missense	proximal	1	no	12.627	12.320	EPSD	ICGC;COSMIC	10.919	Down-regulation
Other_PLK_PLK1_PLK1_ST	O43379	WDR62	P53350	PLK1	S992	P988Q	988	Missense	distal	-4	no	11.431	11.274	EPSD	ICGC;COSMIC	10.919	Down-regulation
Other_PLK_PLK1_PLK1_ST	O43379	WDR62	P53350	PLK1	S1044	P1046L	1046	Missense	proximal	2	no	9.486	11.033	EPSD	ICGC;COSMIC	10.919	Gain
Other_PLK_PLK1_PLK1_ST	O43379	WDR62	P53350	PLK1	S1144	P1145T	1145	Missense	proximal	1	no	12.165	11.636	EPSD	ICGC;COSMIC	10.919	Down-regulation
Other_PLK_PLK1_PLK1_ST	O43379	WDR62	P53350	PLK1	S1144	S1144F	1144	Missense	central	0	yes	12.165	0.000	EPSD	ICGC;COSMIC	10.919	Loss
Other_PLK_PLK1_PLK1_ST	O43379	WDR62	P53350	PLK1	T1159	A1152S	1152	Missense	distal	-7	no	14.045	14.398	EPSD	ICGC;COSMIC	10.919	Up-regulation
Other_PLK_PLK1_PLK1_ST	O43379	WDR62	P53350	PLK1	T1159	R1164H	1164	Missense	distal	5	no	14.045	13.394	EPSD	ICGC;COSMIC	10.919	Down-regulation
Other_PLK_PLK1_PLK1_ST	O43379	WDR62	P53350	PLK1	T1159	W1163C	1163	Missense	distal	4	no	14.045	13.923	EPSD	ICGC	10.919	Down-regulation
Other_PLK_PLK1_PLK1_ST	O43379	WDR62	P53350	PLK1	S1226	R1225H	1225	Missense	proximal	-1	no	10.908	11.905	EPSD	ICGC;COSMIC	10.919	Gain
Other_PLK_PLK1_PLK1_ST	O43379	WDR62	P53350	PLK1	S1226	R1220H	1220	Missense	distal	-6	no	10.908	11.367	EPSD	ICGC;COSMIC	10.919	Gain
Other_PLK_PLK1_PLK1_ST	O43379	WDR62	P53350	PLK1	T1239	R1245S	1245	Missense	distal	6	no	10.639	10.946	EPSD	ICGC;COSMIC	10.919	Gain
Other_PLK_PLK1_PLK1_ST	O43379	WDR62	P53350	PLK1	S1373	T1371N	1371	Missense	proximal	-2	no	9.214	11.162	EPSD	ICGC	10.919	Gain
Other_PLK_PLK1_PLK1_ST	O43379	WDR62	P53350	PLK1	S1410	R1411M	1411	Missense	proximal	1	no	9.150	13.039	EPSD	ICGC;COSMIC	10.919	Gain
Other_PLK_PLK1_PLK1_ST	Q92994	BRF1	P53350	PLK1	S541	R544Q	544	Missense	distal	3	no	12.393	12.589	EPSD	ICGC;COSMIC;GDSC;CCLE	10.919	Up-regulation
Other_PLK_PLK1_PLK1_ST	P25490	YY1	P53350	PLK1	S118	D117E	117	Missense	proximal	-1	no	12.737	11.940	EPSD	ICGC	10.919	Down-regulation
Other_PLK_PLK1_PLK1_ST	P25490	YY1	P53350	PLK1	S118	G114C	114	Missense	distal	-4	no	12.737	12.578	EPSD	ICGC	10.919	Down-regulation
Other_PLK_PLK1_PLK1_ST	P25490	YY1	P53350	PLK1	S118	R122L	122	Missense	distal	4	no	12.737	13.069	EPSD	ICGC	10.919	Up-regulation
Other_PLK_PLK1_PLK1_ST	P25490	YY1	P53350	PLK1	S118	V113L	113	Missense	distal	-5	no	12.737	13.190	EPSD	ICGC;COSMIC	10.919	Up-regulation
Other_PLK_PLK1_PLK1_ST	P25490	YY1	P53350	PLK1	S247	N246S	246	Missense	proximal	-1	no	12.020	12.161	EPSD	ICGC	10.919	Up-regulation
Other_PLK_PLK1_PLK1_ST	P25490	YY1	P53350	PLK1	S247	P248H	248	Missense	proximal	1	no	12.020	11.131	EPSD	ICGC;COSMIC	10.919	Down-regulation
Other_PLK_PLK1_PLK1_ST	P25490	YY1	P53350	PLK1	S252	N246S	246	Missense	distal	-6	no	12.049	12.246	EPSD	ICGC	10.919	Up-regulation
Other_PLK_PLK1_PLK1_ST	P25490	YY1	P53350	PLK1	S252	P248H	248	Missense	distal	-4	no	12.049	11.906	EPSD	ICGC;COSMIC	10.919	Down-regulation
Other_PLK_PLK1_PLK1_ST	O96017	CHEK2	P53350	PLK1	S50	M46I	46	Missense	distal	-4	no	10.693	11.003	EPSD	ICGC;COSMIC	10.919	Gain
Other_PLK_PLK1_PLK1_ST	O96017	CHEK2	P53350	PLK1	S164	N166S	166	Missense	proximal	2	no	11.977	11.763	EPSD;PhosphoSitePlus	ICGC;COSMIC	10.919	Down-regulation
Other_PLK_PLK1_PLK1_ST	O96017	CHEK2	P53350	PLK1	S164	A158V	158	Missense	distal	-6	no	11.977	11.738	EPSD;PhosphoSitePlus	ICGC;COSMIC	10.919	Down-regulation
Other_PLK_PLK1_PLK1_ST	O96017	CHEK2	P53350	PLK1	S164	T168N	168	Missense	distal	4	no	11.977	11.933	EPSD;PhosphoSitePlus	ICGC	10.919	Down-regulation
Other_PLK_PLK1_PLK1_ST	O96017	CHEK2	P53350	PLK1	S164	H163Q	163	Missense	proximal	-1	no	11.977	11.584	EPSD;PhosphoSitePlus	ICGC	10.919	Down-regulation
Other_PLK_PLK1_PLK1_ST	O96017	CHEK2	P53350	PLK1	S164	I157T	157	Missense	distal	-7	no	11.977	12.430	EPSD;PhosphoSitePlus	ICGC;COSMIC	10.919	Up-regulation
Other_PLK_PLK1_PLK1_ST	O96017	CHEK2	P53350	PLK1	S164	D162N	162	Missense	proximal	-2	no	11.977	10.734	EPSD;PhosphoSitePlus	ICGC	10.919	Loss
Other_PLK_PLK1_PLK1_ST	O96017	CHEK2	P53350	PLK1	S164	E161D	161	Missense	distal	-3	no	11.977	12.436	EPSD;PhosphoSitePlus	ICGC	10.919	Up-regulation
Other_PLK_PLK1_PLK1_ST	O96017	CHEK2	P53350	PLK1	S194	R195K	195	Missense	proximal	1	no	10.796	12.201	EPSD	ICGC;COSMIC	10.919	Gain
Other_PLK_PLK1_PLK1_ST	O96017	CHEK2	P53350	PLK1	T205	D203E	203	Missense	proximal	-2	no	12.210	11.816	EPSD;PhosphoSitePlus	ICGC;COSMIC	10.919	Down-regulation
Other_PLK_PLK1_PLK1_ST	O96017	CHEK2	P53350	PLK1	T205	D207H	207	Missense	proximal	2	no	12.210	12.186	EPSD;PhosphoSitePlus	ICGC;COSMIC	10.919	Down-regulation
Other_PLK_PLK1_PLK1_ST	O96017	CHEK2	P53350	PLK1	S210	D203E	203	Missense	distal	-7	no	13.565	13.855	EPSD;PhosphoSitePlus	ICGC;COSMIC	10.919	Up-regulation
Other_PLK_PLK1_PLK1_ST	O96017	CHEK2	P53350	PLK1	S210	D207H	207	Missense	distal	-3	no	13.565	13.435	EPSD;PhosphoSitePlus	ICGC;COSMIC	10.919	Down-regulation
Other_PLK_PLK1_PLK1_ST	O96017	CHEK2	P53350	PLK1	S357	E359K	359	Missense	proximal	2	no	12.026	11.857	EPSD	ICGC;COSMIC	10.919	Down-regulation
Other_PLK_PLK1_PLK1_ST	O96017	CHEK2	P53350	PLK1	S357	L363F	363	Missense	distal	6	no	12.026	11.410	EPSD	ICGC;COSMIC	10.919	Down-regulation
Other_PLK_PLK1_PLK1_ST	O96017	CHEK2	P53350	PLK1	S357	L355R	355	Missense	proximal	-2	no	12.026	12.748	EPSD	ICGC	10.919	Up-regulation
Other_PLK_PLK1_PLK1_ST	O96017	CHEK2	P53350	PLK1	S357	E351D	351	Missense	distal	-6	no	12.026	11.823	EPSD	ICGC;COSMIC	10.919	Down-regulation
Other_PLK_PLK1_PLK1_ST	O96017	CHEK2	P53350	PLK1	S357	L354V	354	Missense	distal	-3	no	12.026	11.376	EPSD	ICGC;COSMIC	10.919	Down-regulation
Other_PLK_PLK1_PLK1_ST	O96017	CHEK2	P53350	PLK1	S379	E377K	377	Missense	proximal	-2	no	11.848	8.970	EPSD	ICGC;COSMIC	10.919	Loss
Other_PLK_PLK1_PLK1_ST	O96017	CHEK2	P53350	PLK1	S379	S379F	379	Missense	central	0	yes	11.848	0.000	EPSD	ICGC;COSMIC	10.919	Loss
Other_PLK_PLK1_PLK1_ST	O96017	CHEK2	P53350	PLK1	S379	K373N	373	Missense	distal	-6	no	11.848	12.106	EPSD	ICGC;COSMIC	10.919	Up-regulation
Other_PLK_PLK1_PLK1_ST	O96017	CHEK2	P53350	PLK1	S379	S372F	372	Missense	distal	-7	no	11.848	11.390	EPSD	ICGC;COSMIC	10.919	Down-regulation
Other_PLK_PLK1_PLK1_ST	O96017	CHEK2	P53350	PLK1	S379	K373E	373	Missense	distal	-6	no	11.848	12.421	EPSD	ICGC;COSMIC;CCLE	10.919	Up-regulation
Other_PLK_PLK1_PLK1_ST	O96017	CHEK2	P53350	PLK1	S379	L380V	380	Missense	proximal	1	no	11.848	11.448	EPSD	ICGC;COSMIC	10.919	Down-regulation
Other_PLK_PLK1_PLK1_ST	O96017	CHEK2	P53350	PLK1	S379	G386V	386	Missense	distal	7	no	11.848	11.897	EPSD	ICGC;COSMIC	10.919	Up-regulation
Other_PLK_PLK1_PLK1_ST	O96017	CHEK2	P53350	PLK1	S379	I374M	374	Missense	distal	-5	no	11.848	11.543	EPSD	ICGC	10.919	Down-regulation
Other_PLK_PLK1_PLK1_ST	O96017	CHEK2	P53350	PLK1	S379	T378A	378	Missense	proximal	-1	no	11.848	12.128	EPSD	ICGC	10.919	Up-regulation
Other_PLK_PLK1_PLK1_ST	O96017	CHEK2	P53350	PLK1	S435	Q433E	433	Missense	proximal	-2	no	8.427	11.086	EPSD	ICGC;COSMIC	10.919	Gain
Other_PLK_PLK1_PLK1_ST	O96017	CHEK2	P53350	PLK1	S456	E450K	450	Missense	distal	-6	no	11.045	10.471	EPSD	ICGC;COSMIC	10.919	Loss
Other_PLK_PLK1_PLK1_ST	O96017	CHEK2	P53350	PLK1	S456	P449T	449	Missense	distal	-7	no	11.045	11.247	EPSD	ICGC	10.919	Up-regulation
Other_PLK_PLK1_PLK1_ST	O96017	CHEK2	P53350	PLK1	S505	A507V	507	Missense	proximal	2	no	11.983	12.427	EPSD	ICGC	10.919	Up-regulation
Other_PLK_PLK1_PLK1_ST	O96017	CHEK2	P53350	PLK1	S505	P509S	509	Missense	distal	4	no	11.983	12.305	EPSD	ICGC;COSMIC	10.919	Up-regulation
Other_PLK_PLK1_PLK1_ST	O60285	NUAK1	P53350	PLK1	S455	S455N	455	Missense	central	0	yes	11.278	0.000	EPSD	ICGC;COSMIC	10.919	Loss
Other_PLK_PLK1_PLK1_ST	O60285	NUAK1	P53350	PLK1	S455	E449Q	449	Missense	distal	-6	no	11.278	11.159	EPSD	ICGC;COSMIC	10.919	Down-regulation
Other_PLK_PLK1_PLK1_ST	O60285	NUAK1	P53350	PLK1	S480	R484C	484	Missense	distal	4	no	10.835	11.253	PhosphoSitePlus;EPSD	ICGC;COSMIC	10.919	Gain
Other_PLK_PLK1_PLK1_ST	O60285	NUAK1	P53350	PLK1	S480	R484H	484	Missense	distal	4	no	10.835	11.258	PhosphoSitePlus;EPSD	ICGC;COSMIC	10.919	Gain
Other_PLK_PLK1_PLK1_ST	O60285	NUAK1	P53350	PLK1	S481	R484C	484	Missense	distal	3	no	13.272	13.331	EPSD	ICGC;COSMIC	10.919	Up-regulation
Other_PLK_PLK1_PLK1_ST	O60285	NUAK1	P53350	PLK1	S481	R484H	484	Missense	distal	3	no	13.272	13.403	EPSD	ICGC;COSMIC	10.919	Up-regulation
Other_PLK_PLK1_PLK1_ST	O60285	NUAK1	P53350	PLK1	S516	K522N	522	Missense	distal	6	no	11.243	11.241	EPSD	ICGC;COSMIC	10.919	Down-regulation
Other_PLK_PLK1_PLK1_ST	O60285	NUAK1	P53350	PLK1	S516	S514Y	514	Missense	proximal	-2	no	11.243	12.353	EPSD	ICGC;COSMIC	10.919	Up-regulation
Other_PLK_PLK1_PLK1_ST	O60285	NUAK1	P53350	PLK1	S550	P543R	543	Missense	distal	-7	no	15.347	15.060	EPSD	ICGC;COSMIC	10.919	Down-regulation
Other_PLK_PLK1_PLK1_ST	O60285	NUAK1	P53350	PLK1	S550	V556A	556	Missense	distal	6	no	15.347	15.522	EPSD	ICGC	10.919	Up-regulation
Other_PLK_PLK1_PLK1_ST	O60285	NUAK1	P53350	PLK1	S570	R563Q	563	Missense	distal	-7	no	11.095	11.495	EPSD	ICGC	10.919	Up-regulation
Other_PLK_PLK1_PLK1_ST	O60285	NUAK1	P53350	PLK1	S636	D634E	634	Missense	proximal	-2	no	17.165	16.771	EPSD	ICGC	10.919	Down-regulation
Other_PLK_PLK1_PLK1_ST	O60285	NUAK1	P53350	PLK1	S636	L632M	632	Missense	distal	-4	no	17.165	17.082	EPSD	ICGC;COSMIC	10.919	Down-regulation
Other_PLK_PLK1_PLK1_ST	O60285	NUAK1	P53350	PLK1	S638	L632M	632	Missense	distal	-6	no	10.721	10.937	EPSD	ICGC;COSMIC	10.919	Gain
Other_PLK_PLK1_PLK1_ST	Q12888	TP53BP1	P53350	PLK1	S25	D24V	24	Missense	proximal	-1	no	14.174	12.425	EPSD	ICGC;COSMIC	10.919	Down-regulation
Other_PLK_PLK1_PLK1_ST	Q12888	TP53BP1	P53350	PLK1	S96	A90S	90	Missense	distal	-6	no	12.375	12.410	EPSD	ICGC;COSMIC	10.919	Up-regulation
Other_PLK_PLK1_PLK1_ST	Q12888	TP53BP1	P53350	PLK1	S96	S95Y	95	Missense	proximal	-1	no	12.375	12.710	EPSD	ICGC	10.919	Up-regulation
Other_PLK_PLK1_PLK1_ST	Q12888	TP53BP1	P53350	PLK1	S96	N97K	97	Missense	proximal	1	no	12.375	11.875	EPSD	ICGC	10.919	Down-regulation
Other_PLK_PLK1_PLK1_ST	Q12888	TP53BP1	P53350	PLK1	S96	D91E	91	Missense	distal	-5	no	12.375	12.033	EPSD	ICGC	10.919	Down-regulation
Other_PLK_PLK1_PLK1_ST	Q12888	TP53BP1	P53350	PLK1	S96	P92T	92	Missense	distal	-4	no	12.375	12.134	EPSD	ICGC	10.919	Down-regulation
Other_PLK_PLK1_PLK1_ST	Q12888	TP53BP1	P53350	PLK1	S176	E183K	183	Missense	distal	7	no	11.814	11.887	EPSD	ICGC	10.919	Up-regulation
Other_PLK_PLK1_PLK1_ST	Q12888	TP53BP1	P53350	PLK1	S176	L173M	173	Missense	distal	-3	no	11.814	11.292	EPSD	ICGC	10.919	Down-regulation
Other_PLK_PLK1_PLK1_ST	Q12888	TP53BP1	P53350	PLK1	S176	Q179H	179	Missense	distal	3	no	11.814	11.749	EPSD	ICGC	10.919	Down-regulation
Other_PLK_PLK1_PLK1_ST	Q12888	TP53BP1	P53350	PLK1	S178	E183K	183	Missense	distal	5	no	11.206	11.217	EPSD	ICGC	10.919	Up-regulation
Other_PLK_PLK1_PLK1_ST	Q12888	TP53BP1	P53350	PLK1	S178	L173M	173	Missense	distal	-5	no	11.206	10.606	EPSD	ICGC	10.919	Loss
Other_PLK_PLK1_PLK1_ST	Q12888	TP53BP1	P53350	PLK1	S178	Q179H	179	Missense	proximal	1	no	11.206	10.624	EPSD	ICGC	10.919	Loss
Other_PLK_PLK1_PLK1_ST	Q12888	TP53BP1	P53350	PLK1	S208	Y204D	204	Missense	distal	-4	no	10.432	10.925	EPSD	ICGC;COSMIC	10.919	Gain
Other_PLK_PLK1_PLK1_ST	Q12888	TP53BP1	P53350	PLK1	S232	S233N	233	Missense	proximal	1	no	11.168	11.908	EPSD	ICGC	10.919	Up-regulation
Other_PLK_PLK1_PLK1_ST	Q12888	TP53BP1	P53350	PLK1	S232	Q231L	231	Missense	proximal	-1	no	11.168	11.041	EPSD	ICGC;COSMIC	10.919	Down-regulation
Other_PLK_PLK1_PLK1_ST	Q12888	TP53BP1	P53350	PLK1	T337	A336D	336	Missense	proximal	-1	no	10.339	11.598	EPSD	ICGC	10.919	Gain
Other_PLK_PLK1_PLK1_ST	Q12888	TP53BP1	P53350	PLK1	T337	P335S	335	Missense	proximal	-2	no	10.339	10.923	EPSD	ICGC;COSMIC	10.919	Gain
Other_PLK_PLK1_PLK1_ST	Q12888	TP53BP1	P53350	PLK1	S354	R348K	348	Missense	distal	-6	no	11.812	11.805	EPSD	ICGC;COSMIC	10.919	Down-regulation
Other_PLK_PLK1_PLK1_ST	Q12888	TP53BP1	P53350	PLK1	S354	D353E	353	Missense	proximal	-1	no	11.812	11.016	EPSD	ICGC;COSMIC	10.919	Down-regulation
Other_PLK_PLK1_PLK1_ST	Q12888	TP53BP1	P53350	PLK1	S354	S359Y	359	Missense	distal	5	no	11.812	11.655	EPSD	ICGC;COSMIC	10.919	Down-regulation
Other_PLK_PLK1_PLK1_ST	Q12888	TP53BP1	P53350	PLK1	S359	D353E	353	Missense	distal	-6	no	10.866	11.069	EPSD	ICGC;COSMIC	10.919	Gain
Other_PLK_PLK1_PLK1_ST	Q12888	TP53BP1	P53350	PLK1	S360	D353E	353	Missense	distal	-7	no	14.922	15.211	EPSD	ICGC;COSMIC	10.919	Up-regulation
Other_PLK_PLK1_PLK1_ST	Q12888	TP53BP1	P53350	PLK1	S360	S359Y	359	Missense	proximal	-1	no	14.922	15.258	EPSD	ICGC;COSMIC	10.919	Up-regulation
Other_PLK_PLK1_PLK1_ST	Q12888	TP53BP1	P53350	PLK1	S366	S359Y	359	Missense	distal	-7	no	11.285	10.673	EPSD	ICGC;COSMIC	10.919	Loss
Other_PLK_PLK1_PLK1_ST	Q12888	TP53BP1	P53350	PLK1	S395	T394S	394	Missense	proximal	-1	no	13.544	14.291	EPSD	ICGC;COSMIC	10.919	Up-regulation
Other_PLK_PLK1_PLK1_ST	Q12888	TP53BP1	P53350	PLK1	S484	T486K	486	Missense	proximal	2	no	11.231	11.110	EPSD	ICGC	10.919	Down-regulation
Other_PLK_PLK1_PLK1_ST	Q12888	TP53BP1	P53350	PLK1	S484	S483L	483	Missense	proximal	-1	no	11.231	10.771	EPSD	ICGC;COSMIC	10.919	Loss
Other_PLK_PLK1_PLK1_ST	Q12888	TP53BP1	P53350	PLK1	T486	S483L	483	Missense	distal	-3	no	10.252	11.026	EPSD	ICGC;COSMIC	10.919	Gain
Other_PLK_PLK1_PLK1_ST	Q12888	TP53BP1	P53350	PLK1	S523	P526Q	526	Missense	distal	3	no	12.026	12.076	EPSD	ICGC;COSMIC	10.919	Up-regulation
Other_PLK_PLK1_PLK1_ST	Q12888	TP53BP1	P53350	PLK1	S523	M528I	528	Missense	distal	5	no	12.026	12.227	EPSD	ICGC;COSMIC	10.919	Up-regulation
Other_PLK_PLK1_PLK1_ST	Q12888	TP53BP1	P53350	PLK1	S523	S523N	523	Missense	central	0	yes	12.026	0.000	EPSD	ICGC	10.919	Loss
Other_PLK_PLK1_PLK1_ST	Q12888	TP53BP1	P53350	PLK1	S523	K527N	527	Missense	distal	4	no	12.026	12.175	EPSD	ICGC;COSMIC	10.919	Up-regulation
Other_PLK_PLK1_PLK1_ST	Q12888	TP53BP1	P53350	PLK1	S530	P526Q	526	Missense	distal	-4	no	11.108	10.952	EPSD	ICGC;COSMIC	10.919	Down-regulation
Other_PLK_PLK1_PLK1_ST	Q12888	TP53BP1	P53350	PLK1	S530	M528I	528	Missense	proximal	-2	no	11.108	11.000	EPSD	ICGC;COSMIC	10.919	Down-regulation
Other_PLK_PLK1_PLK1_ST	Q12888	TP53BP1	P53350	PLK1	S530	S523N	523	Missense	distal	-7	no	11.108	10.898	EPSD	ICGC	10.919	Loss
Other_PLK_PLK1_PLK1_ST	Q12888	TP53BP1	P53350	PLK1	S530	K527N	527	Missense	distal	-3	no	11.108	10.927	EPSD	ICGC;COSMIC	10.919	Down-regulation
Other_PLK_PLK1_PLK1_ST	Q12888	TP53BP1	P53350	PLK1	T543	P550H	550	Missense	distal	7	no	12.733	12.692	EPSD	ICGC;COSMIC	10.919	Down-regulation
Other_PLK_PLK1_PLK1_ST	Q12888	TP53BP1	P53350	PLK1	T543	T548M	548	Missense	distal	5	no	12.733	13.435	EPSD	ICGC;COSMIC	10.919	Up-regulation
Other_PLK_PLK1_PLK1_ST	Q12888	TP53BP1	P53350	PLK1	T543	N542I	542	Missense	proximal	-1	no	12.733	12.890	EPSD	ICGC;COSMIC	10.919	Up-regulation
Other_PLK_PLK1_PLK1_ST	Q12888	TP53BP1	P53350	PLK1	T543	E546D	546	Missense	distal	3	no	12.733	12.799	EPSD	ICGC;COSMIC	10.919	Up-regulation
Other_PLK_PLK1_PLK1_ST	Q12888	TP53BP1	P53350	PLK1	T543	D539E	539	Missense	distal	-4	no	12.733	12.917	EPSD	ICGC;COSMIC	10.919	Up-regulation
Other_PLK_PLK1_PLK1_ST	Q12888	TP53BP1	P53350	PLK1	T543	P550S	550	Missense	distal	7	no	12.733	12.706	EPSD	ICGC;COSMIC	10.919	Down-regulation
Other_PLK_PLK1_PLK1_ST	Q12888	TP53BP1	P53350	PLK1	T543	E549K	549	Missense	distal	6	no	12.733	12.664	EPSD	ICGC;COSMIC	10.919	Down-regulation
Other_PLK_PLK1_PLK1_ST	Q12888	TP53BP1	P53350	PLK1	T543	E541K	541	Missense	proximal	-2	no	12.733	9.856	EPSD	ICGC	10.919	Loss
Other_PLK_PLK1_PLK1_ST	Q12888	TP53BP1	P53350	PLK1	S552	P550H	550	Missense	proximal	-2	no	12.408	12.458	EPSD	ICGC;COSMIC	10.919	Up-regulation
Other_PLK_PLK1_PLK1_ST	Q12888	TP53BP1	P53350	PLK1	S552	T548M	548	Missense	distal	-4	no	12.408	12.494	EPSD	ICGC;COSMIC	10.919	Up-regulation
Other_PLK_PLK1_PLK1_ST	Q12888	TP53BP1	P53350	PLK1	S552	M551L	551	Missense	proximal	-1	no	12.408	11.877	EPSD	ICGC;COSMIC	10.919	Down-regulation
Other_PLK_PLK1_PLK1_ST	Q12888	TP53BP1	P53350	PLK1	S552	E546D	546	Missense	distal	-6	no	12.408	12.206	EPSD	ICGC;COSMIC	10.919	Down-regulation
Other_PLK_PLK1_PLK1_ST	Q12888	TP53BP1	P53350	PLK1	S552	P550S	550	Missense	proximal	-2	no	12.408	12.993	EPSD	ICGC;COSMIC	10.919	Up-regulation
Other_PLK_PLK1_PLK1_ST	Q12888	TP53BP1	P53350	PLK1	S552	E549K	549	Missense	distal	-3	no	12.408	12.949	EPSD	ICGC;COSMIC	10.919	Up-regulation
Other_PLK_PLK1_PLK1_ST	Q12888	TP53BP1	P53350	PLK1	S552	L555V	555	Missense	distal	3	no	12.408	12.707	EPSD	ICGC;COSMIC	10.919	Up-regulation
Other_PLK_PLK1_PLK1_ST	Q12888	TP53BP1	P53350	PLK1	S566	P561R	561	Missense	distal	-5	no	12.265	12.686	EPSD	ICGC;COSMIC	10.919	Up-regulation
Other_PLK_PLK1_PLK1_ST	Q12888	TP53BP1	P53350	PLK1	S566	Q573H	573	Missense	distal	7	no	12.265	12.220	EPSD	ICGC;COSMIC	10.919	Down-regulation
Other_PLK_PLK1_PLK1_ST	Q12888	TP53BP1	P53350	PLK1	S580	Q573H	573	Missense	distal	-7	no	11.140	11.120	EPSD	ICGC;COSMIC	10.919	Down-regulation
Other_PLK_PLK1_PLK1_ST	Q12888	TP53BP1	P53350	PLK1	S580	G575C	575	Missense	distal	-5	no	11.140	10.760	EPSD	ICGC;COSMIC	10.919	Loss
Other_PLK_PLK1_PLK1_ST	Q12888	TP53BP1	P53350	PLK1	S580	D583Y	583	Missense	distal	3	no	11.140	10.714	EPSD	ICGC	10.919	Loss
Other_PLK_PLK1_PLK1_ST	Q12888	TP53BP1	P53350	PLK1	T591	D592Y	592	Missense	proximal	1	no	13.497	13.300	EPSD	ICGC;COSMIC	10.919	Down-regulation
Other_PLK_PLK1_PLK1_ST	Q12888	TP53BP1	P53350	PLK1	T591	D589H	589	Missense	proximal	-2	no	13.497	10.310	EPSD	ICGC;COSMIC	10.919	Loss
Other_PLK_PLK1_PLK1_ST	Q12888	TP53BP1	P53350	PLK1	T591	R594G	594	Missense	distal	3	no	13.497	13.624	EPSD	ICGC;COSMIC	10.919	Up-regulation
Other_PLK_PLK1_PLK1_ST	Q12888	TP53BP1	P53350	PLK1	T591	D596Y	596	Missense	distal	5	no	13.497	13.190	EPSD	ICGC;COSMIC	10.919	Down-regulation
Other_PLK_PLK1_PLK1_ST	Q12888	TP53BP1	P53350	PLK1	S598	D592Y	592	Missense	distal	-6	no	11.367	10.597	EPSD	ICGC;COSMIC	10.919	Loss
Other_PLK_PLK1_PLK1_ST	Q12888	TP53BP1	P53350	PLK1	S598	R594G	594	Missense	distal	-4	no	11.367	11.279	EPSD	ICGC;COSMIC	10.919	Down-regulation
Other_PLK_PLK1_PLK1_ST	Q12888	TP53BP1	P53350	PLK1	S598	D596Y	596	Missense	proximal	-2	no	11.367	9.825	EPSD	ICGC;COSMIC	10.919	Loss
Other_PLK_PLK1_PLK1_ST	Q12888	TP53BP1	P53350	PLK1	S640	S635F	635	Missense	distal	-5	no	11.666	11.405	EPSD	ICGC;COSMIC	10.919	Down-regulation
Other_PLK_PLK1_PLK1_ST	Q12888	TP53BP1	P53350	PLK1	S640	R634Q	634	Missense	distal	-6	no	11.666	12.114	EPSD	ICGC;COSMIC	10.919	Up-regulation
Other_PLK_PLK1_PLK1_ST	Q12888	TP53BP1	P53350	PLK1	S692	P688S	688	Missense	distal	-4	no	10.909	11.031	EPSD	ICGC;COSMIC	10.919	Gain
Other_PLK_PLK1_PLK1_ST	Q12888	TP53BP1	P53350	PLK1	T750	S755I	755	Missense	distal	5	no	12.274	12.572	EPSD	ICGC;COSMIC	10.919	Up-regulation
Other_PLK_PLK1_PLK1_ST	Q12888	TP53BP1	P53350	PLK1	T750	S755R	755	Missense	distal	5	no	12.274	12.619	EPSD	ICGC	10.919	Up-regulation
Other_PLK_PLK1_PLK1_ST	Q12888	TP53BP1	P53350	PLK1	T750	S754F	754	Missense	distal	4	no	12.274	11.460	EPSD	ICGC;COSMIC	10.919	Down-regulation
Other_PLK_PLK1_PLK1_ST	Q12888	TP53BP1	P53350	PLK1	S754	S755I	755	Missense	proximal	1	no	12.441	14.200	EPSD	ICGC;COSMIC	10.919	Up-regulation
Other_PLK_PLK1_PLK1_ST	Q12888	TP53BP1	P53350	PLK1	S754	S755R	755	Missense	proximal	1	no	12.441	11.277	EPSD	ICGC	10.919	Down-regulation
Other_PLK_PLK1_PLK1_ST	Q12888	TP53BP1	P53350	PLK1	S754	S754F	754	Missense	central	0	yes	12.441	0.000	EPSD	ICGC;COSMIC	10.919	Loss
Other_PLK_PLK1_PLK1_ST	Q12888	TP53BP1	P53350	PLK1	S755	S755I	755	Missense	central	0	yes	12.752	0.000	EPSD	ICGC;COSMIC	10.919	Loss
Other_PLK_PLK1_PLK1_ST	Q12888	TP53BP1	P53350	PLK1	S755	S755R	755	Missense	central	0	yes	12.752	0.000	EPSD	ICGC	10.919	Loss
Other_PLK_PLK1_PLK1_ST	Q12888	TP53BP1	P53350	PLK1	S755	S754F	754	Missense	proximal	-1	no	12.752	12.213	EPSD	ICGC;COSMIC	10.919	Down-regulation
Other_PLK_PLK1_PLK1_ST	Q12888	TP53BP1	P53350	PLK1	S765	P764L	764	Missense	proximal	-1	no	10.672	11.386	EPSD	ICGC;COSMIC	10.919	Gain
Other_PLK_PLK1_PLK1_ST	Q12888	TP53BP1	P53350	PLK1	S809	L816R	816	Missense	distal	7	no	13.717	13.734	EPSD	ICGC;COSMIC	10.919	Up-regulation
Other_PLK_PLK1_PLK1_ST	Q12888	TP53BP1	P53350	PLK1	S809	T804S	804	Missense	distal	-5	no	13.717	13.502	EPSD	ICGC	10.919	Down-regulation
Other_PLK_PLK1_PLK1_ST	Q12888	TP53BP1	P53350	PLK1	S809	E806G	806	Missense	distal	-3	no	13.717	14.658	EPSD	ICGC;COSMIC	10.919	Up-regulation
Other_PLK_PLK1_PLK1_ST	Q12888	TP53BP1	P53350	PLK1	S809	D815Y	815	Missense	distal	6	no	13.717	12.918	EPSD	ICGC;COSMIC	10.919	Down-regulation
Other_PLK_PLK1_PLK1_ST	Q12888	TP53BP1	P53350	PLK1	S830	S831L	831	Missense	proximal	1	no	9.031	10.998	EPSD	ICGC;COSMIC	10.919	Gain
Other_PLK_PLK1_PLK1_ST	Q12888	TP53BP1	P53350	PLK1	S862	T855I	855	Missense	distal	-7	no	12.644	12.190	EPSD	ICGC;COSMIC	10.919	Down-regulation
Other_PLK_PLK1_PLK1_ST	Q12888	TP53BP1	P53350	PLK1	S894	S888C	888	Missense	distal	-6	no	11.579	10.376	EPSD	ICGC;COSMIC	10.919	Loss
Other_PLK_PLK1_PLK1_ST	Q12888	TP53BP1	P53350	PLK1	S1002	E1000Q	1000	Missense	proximal	-2	no	13.048	10.388	EPSD	ICGC;GDSC	10.919	Loss
Other_PLK_PLK1_PLK1_ST	Q12888	TP53BP1	P53350	PLK1	S1002	A998V	998	Missense	distal	-4	no	13.048	12.908	EPSD	ICGC;COSMIC	10.919	Down-regulation
Other_PLK_PLK1_PLK1_ST	Q12888	TP53BP1	P53350	PLK1	S1002	L1007P	1007	Missense	distal	5	no	13.048	13.781	EPSD	ICGC	10.919	Up-regulation
Other_PLK_PLK1_PLK1_ST	Q12888	TP53BP1	P53350	PLK1	S1002	E1008K	1008	Missense	distal	6	no	13.048	12.979	EPSD	ICGC	10.919	Down-regulation
Other_PLK_PLK1_PLK1_ST	Q12888	TP53BP1	P53350	PLK1	T1082	E1075Q	1075	Missense	distal	-7	no	11.631	11.596	EPSD	ICGC;COSMIC	10.919	Down-regulation
Other_PLK_PLK1_PLK1_ST	Q12888	TP53BP1	P53350	PLK1	T1082	D1080E	1080	Missense	proximal	-2	no	11.631	11.238	EPSD	ICGC	10.919	Down-regulation
Other_PLK_PLK1_PLK1_ST	Q12888	TP53BP1	P53350	PLK1	T1082	Q1085K	1085	Missense	distal	3	no	11.631	11.533	EPSD	ICGC	10.919	Down-regulation
Other_PLK_PLK1_PLK1_ST	Q12888	TP53BP1	P53350	PLK1	T1082	G1079C	1079	Missense	distal	-3	no	11.631	10.895	EPSD	ICGC;COSMIC	10.919	Loss
Other_PLK_PLK1_PLK1_ST	Q12888	TP53BP1	P53350	PLK1	S1094	I1093F	1093	Missense	proximal	-1	no	12.290	11.734	EPSD	ICGC;COSMIC	10.919	Down-regulation
Other_PLK_PLK1_PLK1_ST	Q12888	TP53BP1	P53350	PLK1	S1094	S1101Y	1101	Missense	distal	7	no	12.290	12.346	EPSD	ICGC;COSMIC	10.919	Up-regulation
Other_PLK_PLK1_PLK1_ST	Q12888	TP53BP1	P53350	PLK1	S1160	E1165K	1165	Missense	distal	5	no	12.940	12.951	EPSD	ICGC;COSMIC	10.919	Up-regulation
Other_PLK_PLK1_PLK1_ST	Q12888	TP53BP1	P53350	PLK1	S1160	L1161F	1161	Missense	proximal	1	no	12.940	14.021	EPSD	ICGC;COSMIC	10.919	Up-regulation
Other_PLK_PLK1_PLK1_ST	Q12888	TP53BP1	P53350	PLK1	S1160	M1157R	1157	Missense	distal	-3	no	12.940	13.520	EPSD	ICGC;COSMIC	10.919	Up-regulation
Other_PLK_PLK1_PLK1_ST	Q12888	TP53BP1	P53350	PLK1	S1160	G1153V	1153	Missense	distal	-7	no	12.940	13.339	EPSD	ICGC;COSMIC	10.919	Up-regulation
Other_PLK_PLK1_PLK1_ST	Q12888	TP53BP1	P53350	PLK1	T1195	N1188S	1188	Missense	distal	-7	no	11.765	11.975	EPSD	ICGC;COSMIC	10.919	Up-regulation
Other_PLK_PLK1_PLK1_ST	Q12888	TP53BP1	P53350	PLK1	T1195	A1194T	1194	Missense	proximal	-1	no	11.765	11.485	EPSD	ICGC;COSMIC	10.919	Down-regulation
Other_PLK_PLK1_PLK1_ST	Q12888	TP53BP1	P53350	PLK1	T1195	S1202R	1202	Missense	distal	7	no	11.765	11.781	EPSD	ICGC	10.919	Up-regulation
Other_PLK_PLK1_PLK1_ST	Q12888	TP53BP1	P53350	PLK1	T1214	G1211W	1211	Missense	distal	-3	no	11.666	10.943	EPSD	ICGC;COSMIC	10.919	Down-regulation
Other_PLK_PLK1_PLK1_ST	Q12888	TP53BP1	P53350	PLK1	T1214	A1209V	1209	Missense	distal	-5	no	11.666	11.593	EPSD	ICGC;COSMIC	10.919	Down-regulation
Other_PLK_PLK1_PLK1_ST	Q12888	TP53BP1	P53350	PLK1	T1273	R1267I	1267	Missense	distal	-6	no	11.876	12.392	EPSD	ICGC;COSMIC	10.919	Up-regulation
Other_PLK_PLK1_PLK1_ST	Q12888	TP53BP1	P53350	PLK1	T1273	E1266K	1266	Missense	distal	-7	no	11.876	11.572	EPSD	ICGC;COSMIC	10.919	Down-regulation
Other_PLK_PLK1_PLK1_ST	Q12888	TP53BP1	P53350	PLK1	S1288	C1283R	1283	Missense	distal	-5	no	14.100	14.765	EPSD	ICGC;COSMIC	10.919	Up-regulation
Other_PLK_PLK1_PLK1_ST	Q12888	TP53BP1	P53350	PLK1	S1303	S1306F	1306	Missense	distal	3	no	11.475	11.534	EPSD	ICGC;COSMIC	10.919	Up-regulation
Other_PLK_PLK1_PLK1_ST	Q12888	TP53BP1	P53350	PLK1	S1303	S1310P	1310	Missense	distal	7	no	11.475	11.502	EPSD	ICGC;COSMIC	10.919	Up-regulation
Other_PLK_PLK1_PLK1_ST	Q12888	TP53BP1	P53350	PLK1	S1303	D1301A	1301	Missense	proximal	-2	no	11.475	8.903	EPSD	ICGC;COSMIC	10.919	Loss
Other_PLK_PLK1_PLK1_ST	Q12888	TP53BP1	P53350	PLK1	S1304	D1301A	1301	Missense	distal	-3	no	10.721	10.953	EPSD	ICGC;COSMIC	10.919	Gain
Other_PLK_PLK1_PLK1_ST	Q12888	TP53BP1	P53350	PLK1	S1311	S1306F	1306	Missense	distal	-5	no	12.940	12.679	EPSD	ICGC;COSMIC	10.919	Down-regulation
Other_PLK_PLK1_PLK1_ST	Q12888	TP53BP1	P53350	PLK1	S1311	S1310P	1310	Missense	proximal	-1	no	12.940	11.766	EPSD	ICGC;COSMIC	10.919	Down-regulation
Other_PLK_PLK1_PLK1_ST	Q12888	TP53BP1	P53350	PLK1	S1311	G1318R	1318	Missense	distal	7	no	12.940	12.957	EPSD	ICGC;COSMIC	10.919	Up-regulation
Other_PLK_PLK1_PLK1_ST	Q12888	TP53BP1	P53350	PLK1	S1317	L1321F	1321	Missense	distal	4	no	11.305	11.104	EPSD	ICGC;COSMIC	10.919	Down-regulation
Other_PLK_PLK1_PLK1_ST	Q12888	TP53BP1	P53350	PLK1	S1317	S1310P	1310	Missense	distal	-7	no	11.305	11.095	EPSD	ICGC;COSMIC	10.919	Down-regulation
Other_PLK_PLK1_PLK1_ST	Q12888	TP53BP1	P53350	PLK1	S1317	L1321I	1321	Missense	distal	4	no	11.305	10.726	EPSD	ICGC;COSMIC	10.919	Loss
Other_PLK_PLK1_PLK1_ST	Q12888	TP53BP1	P53350	PLK1	S1317	G1318R	1318	Missense	proximal	1	no	11.305	9.204	EPSD	ICGC;COSMIC	10.919	Loss
Other_PLK_PLK1_PLK1_ST	Q12888	TP53BP1	P53350	PLK1	S1426	S1430P	1430	Missense	distal	4	no	13.355	13.033	EPSD	ICGC;COSMIC	10.919	Down-regulation
Other_PLK_PLK1_PLK1_ST	Q12888	TP53BP1	P53350	PLK1	S1426	D1424E	1424	Missense	proximal	-2	no	13.355	12.961	EPSD	ICGC	10.919	Down-regulation
Other_PLK_PLK1_PLK1_ST	Q12888	TP53BP1	P53350	PLK1	S1426	D1432N	1432	Missense	distal	6	no	13.355	13.135	EPSD	ICGC;COSMIC	10.919	Down-regulation
Other_PLK_PLK1_PLK1_ST	Q12888	TP53BP1	P53350	PLK1	S1435	S1430P	1430	Missense	distal	-5	no	14.652	14.914	EPSD	ICGC;COSMIC	10.919	Up-regulation
Other_PLK_PLK1_PLK1_ST	Q12888	TP53BP1	P53350	PLK1	S1435	R1438S	1438	Missense	distal	3	no	14.652	14.776	EPSD	ICGC;COSMIC	10.919	Up-regulation
Other_PLK_PLK1_PLK1_ST	Q12888	TP53BP1	P53350	PLK1	S1435	P1441T	1441	Missense	distal	6	no	14.652	14.784	EPSD	ICGC	10.919	Up-regulation
Other_PLK_PLK1_PLK1_ST	Q12888	TP53BP1	P53350	PLK1	S1435	D1432N	1432	Missense	distal	-3	no	14.652	14.551	EPSD	ICGC;COSMIC	10.919	Down-regulation
Other_PLK_PLK1_PLK1_ST	Q12888	TP53BP1	P53350	PLK1	S1462	G1455D	1455	Missense	distal	-7	no	12.059	12.405	EPSD	ICGC;COSMIC	10.919	Up-regulation
Other_PLK_PLK1_PLK1_ST	Q12888	TP53BP1	P53350	PLK1	S1462	R1458C	1458	Missense	distal	-4	no	12.059	11.813	EPSD	ICGC;COSMIC	10.919	Down-regulation
Other_PLK_PLK1_PLK1_ST	Q12888	TP53BP1	P53350	PLK1	S1462	P1466S	1466	Missense	distal	4	no	12.059	12.381	EPSD	ICGC;COSMIC	10.919	Up-regulation
Other_PLK_PLK1_PLK1_ST	Q12888	TP53BP1	P53350	PLK1	S1462	R1459H	1459	Missense	distal	-3	no	12.059	11.387	EPSD	ICGC;COSMIC	10.919	Down-regulation
Other_PLK_PLK1_PLK1_ST	Q12888	TP53BP1	P53350	PLK1	T1545	A1546D	1546	Missense	proximal	1	no	10.604	11.409	EPSD	ICGC	10.919	Gain
Other_PLK_PLK1_PLK1_ST	Q12888	TP53BP1	P53350	PLK1	T1545	V1544M	1544	Missense	proximal	-1	no	10.604	11.633	EPSD	ICGC;COSMIC	10.919	Gain
Other_PLK_PLK1_PLK1_ST	Q12888	TP53BP1	P53350	PLK1	S1571	E1573Q	1573	Missense	proximal	2	no	13.488	13.677	EPSD	ICGC;COSMIC	10.919	Up-regulation
Other_PLK_PLK1_PLK1_ST	Q12888	TP53BP1	P53350	PLK1	S1571	Q1577K	1577	Missense	distal	6	no	13.488	13.560	EPSD	ICGC	10.919	Up-regulation
Other_PLK_PLK1_PLK1_ST	Q12888	TP53BP1	P53350	PLK1	S1571	R1578G	1578	Missense	distal	7	no	13.488	13.471	EPSD	ICGC	10.919	Down-regulation
Other_PLK_PLK1_PLK1_ST	Q12888	TP53BP1	P53350	PLK1	S1571	R1578I	1578	Missense	distal	7	no	13.488	13.505	EPSD	ICGC;COSMIC	10.919	Up-regulation
Other_PLK_PLK1_PLK1_ST	Q12888	TP53BP1	P53350	PLK1	S1618	I1617S	1617	Missense	proximal	-1	no	12.606	12.589	PhosphoSitePlus	ICGC;COSMIC	10.919	Down-regulation
Other_PLK_PLK1_PLK1_ST	Q12888	TP53BP1	P53350	PLK1	S1618	K1613E	1613	Missense	distal	-5	no	12.606	12.362	PhosphoSitePlus	ICGC	10.919	Down-regulation
Other_PLK_PLK1_PLK1_ST	Q12888	TP53BP1	P53350	PLK1	S1618	L1611V	1611	Missense	distal	-7	no	12.606	12.614	PhosphoSitePlus	ICGC;COSMIC	10.919	Up-regulation
Other_PLK_PLK1_PLK1_ST	Q12888	TP53BP1	P53350	PLK1	S1618	A1614G	1614	Missense	distal	-4	no	12.606	11.912	PhosphoSitePlus	ICGC;COSMIC	10.919	Down-regulation
Other_PLK_PLK1_PLK1_ST	Q12888	TP53BP1	P53350	PLK1	S1631	P1636S	1636	Missense	distal	5	no	11.235	10.848	EPSD	ICGC;COSMIC	10.919	Loss
Other_PLK_PLK1_PLK1_ST	Q12888	TP53BP1	P53350	PLK1	S1631	R1627L	1627	Missense	distal	-4	no	11.235	11.608	EPSD	ICGC;COSMIC	10.919	Up-regulation
Other_PLK_PLK1_PLK1_ST	Q12888	TP53BP1	P53350	PLK1	S1646	S1644N	1644	Missense	proximal	-2	no	9.645	11.055	EPSD	ICGC;COSMIC	10.919	Gain
Other_PLK_PLK1_PLK1_ST	Q12888	TP53BP1	P53350	PLK1	S1656	V1663I	1663	Missense	distal	7	no	11.479	11.463	EPSD	ICGC;COSMIC	10.919	Down-regulation
Other_PLK_PLK1_PLK1_ST	Q12888	TP53BP1	P53350	PLK1	S1656	P1657L	1657	Missense	proximal	1	no	11.479	12.325	EPSD	ICGC;COSMIC	10.919	Up-regulation
Other_PLK_PLK1_PLK1_ST	Q12888	TP53BP1	P53350	PLK1	T1709	P1702S	1702	Missense	distal	-7	no	11.663	11.874	EPSD	ICGC;COSMIC	10.919	Up-regulation
Other_PLK_PLK1_PLK1_ST	Q12888	TP53BP1	P53350	PLK1	S1759	E1760D	1760	Missense	proximal	1	no	10.752	10.996	EPSD	ICGC;COSMIC	10.919	Gain
Other_PLK_PLK1_PLK1_ST	Q12888	TP53BP1	P53350	PLK1	S1929	S1929L	1929	Missense	central	0	yes	11.665	0.000	EPSD	ICGC	10.919	Loss
Other_PLK_PLK1_PLK1_ST	Q12888	TP53BP1	P53350	PLK1	S1929	T1922M	1922	Missense	distal	-7	no	11.665	11.244	EPSD	ICGC;COSMIC	10.919	Down-regulation
Other_PLK_PLK1_PLK1_ST	P08670	VIM	P53350	PLK1	S29	P24L	24	Missense	distal	-5	no	12.166	12.568	EPSD	ICGC;COSMIC	10.919	Up-regulation
Other_PLK_PLK1_PLK1_ST	P08670	VIM	P53350	PLK1	S29	V31A	31	Missense	proximal	2	no	12.166	11.723	EPSD	ICGC	10.919	Down-regulation
Other_PLK_PLK1_PLK1_ST	P08670	VIM	P53350	PLK1	S29	R36S	36	Missense	distal	7	no	12.166	12.150	EPSD	ICGC;COSMIC	10.919	Down-regulation
Other_PLK_PLK1_PLK1_ST	P08670	VIM	P53350	PLK1	S87	A91S	91	Missense	distal	4	no	14.167	14.366	EPSD	ICGC;COSMIC	10.919	Up-regulation
Other_PLK_PLK1_PLK1_ST	P08670	VIM	P53350	PLK1	T202	R207G	207	Missense	distal	5	no	11.627	11.466	EPSD	ICGC;COSMIC	10.919	Down-regulation
Other_PLK_PLK1_PLK1_ST	P08670	VIM	P53350	PLK1	S226	E229D	229	Missense	distal	3	no	10.880	10.946	EPSD	ICGC;COSMIC	10.919	Gain
Other_PLK_PLK1_PLK1_ST	P08670	VIM	P53350	PLK1	S293	E286K	286	Missense	distal	-7	no	11.059	10.755	EPSD	ICGC	10.919	Loss
Other_PLK_PLK1_PLK1_ST	P08670	VIM	P53350	PLK1	S299	A302V	302	Missense	distal	3	no	13.360	13.688	EPSD	ICGC;COSMIC	10.919	Up-regulation
Other_PLK_PLK1_PLK1_ST	P08670	VIM	P53350	PLK1	S325	S325Y	325	Missense	central	0	yes	11.748	0.000	EPSD	ICGC;COSMIC	10.919	Loss
Other_PLK_PLK1_PLK1_ST	P08670	VIM	P53350	PLK1	S325	D331E	331	Missense	distal	6	no	11.748	11.598	EPSD	ICGC;COSMIC	10.919	Down-regulation
Other_PLK_PLK1_PLK1_ST	P08670	VIM	P53350	PLK1	S325	V323L	323	Missense	proximal	-2	no	11.748	10.760	EPSD	ICGC;COSMIC	10.919	Loss
Other_PLK_PLK1_PLK1_ST	P08670	VIM	P53350	PLK1	S430	L428P	428	Missense	proximal	-2	no	10.922	11.285	EPSD	ICGC;COSMIC	10.919	Up-regulation
Other_PLK_PLK1_PLK1_ST	P08670	VIM	P53350	PLK1	T446	V447F	447	Missense	proximal	1	no	9.827	11.307	EPSD	ICGC	10.919	Gain
Other_PLK_PLK1_PLK1_ST	P08670	VIM	P53350	PLK1	S459	D463N	463	Missense	distal	4	no	11.973	11.734	EPSD	ICGC;COSMIC	10.919	Down-regulation
Other_PLK_PLK1_PLK1_ST	P08670	VIM	P53350	PLK1	S459	S459C	459	Missense	central	0	yes	11.973	0.000	EPSD	ICGC;COSMIC	10.919	Loss
Other_PLK_PLK1_PLK1_ST	O95425	SVIL	P53350	PLK1	S66	E60D	60	Missense	distal	-6	no	13.619	13.416	EPSD	ICGC;COSMIC	10.919	Down-regulation
Other_PLK_PLK1_PLK1_ST	O95425	SVIL	P53350	PLK1	S80	G84D	84	Missense	distal	4	no	10.831	10.920	EPSD	ICGC;COSMIC	10.919	Gain
Other_PLK_PLK1_PLK1_ST	O95425	SVIL	P53350	PLK1	S86	G84D	84	Missense	proximal	-2	no	10.509	13.831	EPSD	ICGC;COSMIC	10.919	Gain
Other_PLK_PLK1_PLK1_ST	O95425	SVIL	P53350	PLK1	S193	G192S	192	Missense	proximal	-1	no	9.758	11.555	EPSD	ICGC;COSMIC	10.919	Gain
Other_PLK_PLK1_PLK1_ST	O95425	SVIL	P53350	PLK1	S238	R244L	244	Missense	distal	6	no	15.559	15.906	PhosphoSitePlus	ICGC;COSMIC	10.919	Up-regulation
Other_PLK_PLK1_PLK1_ST	O95425	SVIL	P53350	PLK1	S238	R235I	235	Missense	distal	-3	no	15.559	15.127	PhosphoSitePlus	ICGC	10.919	Down-regulation
Other_PLK_PLK1_PLK1_ST	O95425	SVIL	P53350	PLK1	S261	R260Q	260	Missense	proximal	-1	no	12.185	12.789	EPSD	ICGC;COSMIC	10.919	Up-regulation
Other_PLK_PLK1_PLK1_ST	O95425	SVIL	P53350	PLK1	S315	R317G	317	Missense	proximal	2	no	13.327	12.474	EPSD	ICGC	10.919	Down-regulation
Other_PLK_PLK1_PLK1_ST	O95425	SVIL	P53350	PLK1	S341	A335V	335	Missense	distal	-6	no	13.673	13.434	EPSD	ICGC;COSMIC	10.919	Down-regulation
Other_PLK_PLK1_PLK1_ST	O95425	SVIL	P53350	PLK1	S341	A348D	348	Missense	distal	7	no	13.673	13.622	EPSD	ICGC	10.919	Down-regulation
Other_PLK_PLK1_PLK1_ST	O95425	SVIL	P53350	PLK1	S341	A335E	335	Missense	distal	-6	no	13.673	13.828	EPSD	ICGC	10.919	Up-regulation
Other_PLK_PLK1_PLK1_ST	O95425	SVIL	P53350	PLK1	S472	P471T	471	Missense	proximal	-1	no	10.610	11.037	EPSD	ICGC	10.919	Gain
Other_PLK_PLK1_PLK1_ST	O95425	SVIL	P53350	PLK1	S538	R544C	544	Missense	distal	6	no	11.156	10.530	EPSD	ICGC;COSMIC	10.919	Loss
Other_PLK_PLK1_PLK1_ST	O95425	SVIL	P53350	PLK1	S538	R544S	544	Missense	distal	6	no	11.156	11.463	EPSD	ICGC	10.919	Up-regulation
Other_PLK_PLK1_PLK1_ST	O95425	SVIL	P53350	PLK1	S538	R541C	541	Missense	distal	3	no	11.156	11.215	EPSD	ICGC;COSMIC	10.919	Up-regulation
Other_PLK_PLK1_PLK1_ST	O95425	SVIL	P53350	PLK1	S549	R544C	544	Missense	distal	-5	no	11.073	10.407	EPSD	ICGC;COSMIC	10.919	Loss
Other_PLK_PLK1_PLK1_ST	O95425	SVIL	P53350	PLK1	S549	R544S	544	Missense	distal	-5	no	11.073	10.389	EPSD	ICGC	10.919	Loss
Other_PLK_PLK1_PLK1_ST	O95425	SVIL	P53350	PLK1	S644	R641S	641	Missense	distal	-3	no	11.462	10.631	EPSD	ICGC	10.919	Loss
Other_PLK_PLK1_PLK1_ST	O95425	SVIL	P53350	PLK1	S644	P639L	639	Missense	distal	-5	no	11.462	11.864	EPSD	ICGC	10.919	Up-regulation
Other_PLK_PLK1_PLK1_ST	O95425	SVIL	P53350	PLK1	S644	S644F	644	Missense	central	0	yes	11.462	0.000	EPSD	ICGC;COSMIC	10.919	Loss
Other_PLK_PLK1_PLK1_ST	O95425	SVIL	P53350	PLK1	S734	P738T	738	Missense	distal	4	no	14.484	14.614	EPSD	ICGC;COSMIC	10.919	Up-regulation
Other_PLK_PLK1_PLK1_ST	O95425	SVIL	P53350	PLK1	S734	R733M	733	Missense	proximal	-1	no	14.484	15.493	EPSD	ICGC	10.919	Up-regulation
Other_PLK_PLK1_PLK1_ST	O95425	SVIL	P53350	PLK1	S734	D732G	732	Missense	proximal	-2	no	14.484	11.163	EPSD	ICGC	10.919	Down-regulation
Other_PLK_PLK1_PLK1_ST	O95425	SVIL	P53350	PLK1	S734	S734Y	734	Missense	central	0	yes	14.484	0.000	EPSD	ICGC	10.919	Loss
Other_PLK_PLK1_PLK1_ST	O95425	SVIL	P53350	PLK1	T736	S734Y	734	Missense	proximal	-2	no	9.952	11.063	EPSD	ICGC	10.919	Gain
Other_PLK_PLK1_PLK1_ST	O95425	SVIL	P53350	PLK1	S811	S811Y	811	Missense	central	0	yes	13.877	0.000	EPSD	ICGC	10.919	Loss
Other_PLK_PLK1_PLK1_ST	O95425	SVIL	P53350	PLK1	S811	E817K	817	Missense	distal	6	no	13.877	13.808	EPSD	ICGC;COSMIC	10.919	Down-regulation
Other_PLK_PLK1_PLK1_ST	O95425	SVIL	P53350	PLK1	S811	P808H	808	Missense	distal	-3	no	13.877	14.455	EPSD	ICGC	10.919	Up-regulation
Other_PLK_PLK1_PLK1_ST	O95425	SVIL	P53350	PLK1	T852	R849H	849	Missense	distal	-3	no	11.402	10.730	EPSD	ICGC;COSMIC	10.919	Loss
Other_PLK_PLK1_PLK1_ST	O95425	SVIL	P53350	PLK1	T852	N847D	847	Missense	distal	-5	no	11.402	11.698	EPSD	ICGC	10.919	Up-regulation
Other_PLK_PLK1_PLK1_ST	O95425	SVIL	P53350	PLK1	S905	D908N	908	Missense	distal	3	no	11.090	10.890	EPSD	ICGC	10.919	Loss
Other_PLK_PLK1_PLK1_ST	O95425	SVIL	P53350	PLK1	S938	G937C	937	Missense	proximal	-1	no	11.444	11.381	EPSD	ICGC	10.919	Down-regulation
Other_PLK_PLK1_PLK1_ST	O95425	SVIL	P53350	PLK1	S968	S975Y	975	Missense	distal	7	no	14.941	14.996	EPSD	ICGC	10.919	Up-regulation
Other_PLK_PLK1_PLK1_ST	O95425	SVIL	P53350	PLK1	T1230	P1231L	1231	Missense	proximal	1	no	11.758	12.604	EPSD	ICGC;COSMIC	10.919	Up-regulation
Other_PLK_PLK1_PLK1_ST	O95425	SVIL	P53350	PLK1	T1230	A1228V	1228	Missense	proximal	-2	no	11.758	11.718	EPSD	ICGC	10.919	Down-regulation
Other_PLK_PLK1_PLK1_ST	O95425	SVIL	P53350	PLK1	S1314	R1313S	1313	Missense	proximal	-1	no	10.894	11.830	EPSD	ICGC	10.919	Gain
Other_PLK_PLK1_PLK1_ST	O95425	SVIL	P53350	PLK1	T1379	L1374R	1374	Missense	distal	-5	no	12.068	12.088	EPSD	ICGC;COSMIC	10.919	Up-regulation
Other_PLK_PLK1_PLK1_ST	O95425	SVIL	P53350	PLK1	T1379	Q1381H	1381	Missense	proximal	2	no	12.068	12.445	EPSD	ICGC;COSMIC	10.919	Up-regulation
Other_PLK_PLK1_PLK1_ST	O95425	SVIL	P53350	PLK1	S1911	R1907G	1907	Missense	distal	-4	no	11.912	11.824	EPSD	ICGC;COSMIC	10.919	Down-regulation
Other_PLK_PLK1_PLK1_ST	O95425	SVIL	P53350	PLK1	S1911	V1917I	1917	Missense	distal	6	no	11.912	11.806	EPSD	ICGC	10.919	Down-regulation
Other_PLK_PLK1_PLK1_ST	Q9UJX2	CDC23	P53350	PLK1	S21	A17E	17	Missense	distal	-4	no	11.022	10.972	EPSD	ICGC;COSMIC	10.919	Down-regulation
Other_PLK_PLK1_PLK1_ST	Q9UJX2	CDC23	P53350	PLK1	S21	N23K	23	Missense	proximal	2	no	11.022	10.047	EPSD	ICGC;COSMIC	10.919	Loss
Other_PLK_PLK1_PLK1_ST	Q9UJX2	CDC23	P53350	PLK1	S27	R30L	30	Missense	distal	3	no	14.419	14.397	EPSD	ICGC;COSMIC	10.919	Down-regulation
Other_PLK_PLK1_PLK1_ST	Q9UJX2	CDC23	P53350	PLK1	S27	N23K	23	Missense	distal	-4	no	14.419	14.161	EPSD	ICGC;COSMIC	10.919	Down-regulation
Other_PLK_PLK1_PLK1_ST	Q9UJX2	CDC23	P53350	PLK1	T134	P140S	140	Missense	distal	6	no	12.873	12.728	EPSD	ICGC	10.919	Down-regulation
Other_PLK_PLK1_PLK1_ST	Q9UJX2	CDC23	P53350	PLK1	T565	E566K	566	Missense	proximal	1	no	11.542	11.091	EPSD;PhosphoSitePlus	ICGC;COSMIC;GDSC;CCLE	10.919	Down-regulation
Other_PLK_PLK1_PLK1_ST	Q9UJX2	CDC23	P53350	PLK1	T565	E566A	566	Missense	proximal	1	no	11.542	10.981	EPSD;PhosphoSitePlus	ICGC;COSMIC	10.919	Down-regulation
Other_PLK_PLK1_PLK1_ST	P30291	WEE1	P53350	PLK1	S45	E40G	40	Missense	distal	-5	no	10.641	11.138	EPSD	ICGC;COSMIC	10.919	Gain
Other_PLK_PLK1_PLK1_ST	P30291	WEE1	P53350	PLK1	S123	A130V	130	Missense	distal	7	no	13.184	13.207	EPSD	ICGC;COSMIC	10.919	Up-regulation
Other_PLK_PLK1_PLK1_ST	P30291	WEE1	P53350	PLK1	S137	A130V	130	Missense	distal	-7	no	11.875	11.932	EPSD	ICGC;COSMIC	10.919	Up-regulation
Other_PLK_PLK1_PLK1_ST	P30291	WEE1	P53350	PLK1	S204	D202Y	202	Missense	proximal	-2	no	12.170	10.628	EPSD	ICGC;COSMIC	10.919	Loss
Other_PLK_PLK1_PLK1_ST	P30291	WEE1	P53350	PLK1	S204	G210C	210	Missense	distal	6	no	12.170	11.441	EPSD	ICGC;COSMIC	10.919	Down-regulation
Other_PLK_PLK1_PLK1_ST	P30291	WEE1	P53350	PLK1	S242	P240Q	240	Missense	proximal	-2	no	11.613	11.796	EPSD	ICGC;COSMIC	10.919	Up-regulation
Other_PLK_PLK1_PLK1_ST	P30291	WEE1	P53350	PLK1	S289	R294L	294	Missense	distal	5	no	12.095	11.405	EPSD	ICGC	10.919	Down-regulation
Other_PLK_PLK1_PLK1_ST	P30291	WEE1	P53350	PLK1	S293	R294L	294	Missense	proximal	1	no	8.832	11.964	EPSD	ICGC	10.919	Gain
Other_PLK_PLK1_PLK1_ST	P30291	WEE1	P53350	PLK1	S640	R639C	639	Missense	proximal	-1	no	13.160	12.236	EPSD	ICGC;COSMIC	10.919	Down-regulation
Other_PLK_PLK1_PLK1_ST	P30291	WEE1	P53350	PLK1	S640	S642I	642	Missense	proximal	2	no	13.160	13.581	EPSD	ICGC;COSMIC	10.919	Up-regulation
Other_PLK_PLK1_PLK1_ST	O60341	KDM1A	P53350	PLK1	S126	N129K	129	Missense	distal	3	no	16.215	16.143	PhosphoSitePlus	ICGC;COSMIC	10.919	Down-regulation
Other_PLK_PLK1_PLK1_ST	O60341	KDM1A	P53350	PLK1	S131	N129K	129	Missense	proximal	-2	no	10.958	8.930	EPSD	ICGC;COSMIC	10.919	Loss
Other_PLK_PLK1_PLK1_ST	O60341	KDM1A	P53350	PLK1	S172	G173R	173	Missense	proximal	1	no	12.204	10.103	EPSD	ICGC	10.919	Loss
Other_PLK_PLK1_PLK1_ST	O60341	KDM1A	P53350	PLK1	S172	S172L	172	Missense	central	0	yes	12.204	0.000	EPSD	ICGC;COSMIC	10.919	Loss
Other_PLK_PLK1_PLK1_ST	Q9Y2Z0	SUGT1	P53350	PLK1	S71	K69N	69	Missense	proximal	-2	no	10.402	12.431	EPSD	ICGC;COSMIC	10.919	Gain
Other_PLK_PLK1_PLK1_ST	Q9Y2Z0	SUGT1	P53350	PLK1	S331	E334D	334	Missense	distal	3	no	14.665	14.731	PhosphoSitePlus	ICGC;COSMIC	10.919	Up-regulation
Other_PLK_PLK1_PLK1_ST	Q9Y2Z0	SUGT1	P53350	PLK1	S331	N329K	329	Missense	proximal	-2	no	14.665	12.636	PhosphoSitePlus	ICGC;COSMIC	10.919	Down-regulation
Other_PLK_PLK1_PLK1_ST	O15350	TP73	P53350	PLK1	T27	S20I	20	Missense	distal	-7	no	13.888	13.426	PhosphoSitePlus	ICGC	10.919	Down-regulation
Other_PLK_PLK1_PLK1_ST	O15350	TP73	P53350	PLK1	T27	D30Y	30	Missense	distal	3	no	13.888	13.462	PhosphoSitePlus	ICGC	10.919	Down-regulation
Other_PLK_PLK1_PLK1_ST	O15350	TP73	P53350	PLK1	S47	S48I	48	Missense	proximal	1	no	10.228	11.987	EPSD	ICGC;COSMIC	10.919	Gain
Other_PLK_PLK1_PLK1_ST	O15350	TP73	P53350	PLK1	S48	G43D	43	Missense	distal	-5	no	14.479	14.324	EPSD	ICGC	10.919	Down-regulation
Other_PLK_PLK1_PLK1_ST	O15350	TP73	P53350	PLK1	S48	S48I	48	Missense	central	0	yes	14.479	0.000	EPSD	ICGC;COSMIC	10.919	Loss
Other_PLK_PLK1_PLK1_ST	O15350	TP73	P53350	PLK1	S48	G44R	44	Missense	distal	-4	no	14.479	14.566	EPSD	ICGC;COSMIC;GDSC;CCLE	10.919	Up-regulation
Other_PLK_PLK1_PLK1_ST	O15350	TP73	P53350	PLK1	T167	P168L	168	Missense	proximal	1	no	11.790	12.636	EPSD	ICGC;COSMIC	10.919	Up-regulation
Other_PLK_PLK1_PLK1_ST	O15350	TP73	P53350	PLK1	T167	P160S	160	Missense	distal	-7	no	11.790	12.001	EPSD	ICGC	10.919	Up-regulation
Other_PLK_PLK1_PLK1_ST	O15350	TP73	P53350	PLK1	S235	V230A	230	Missense	distal	-5	no	11.099	11.171	EPSD	ICGC;COSMIC	10.919	Up-regulation
Other_PLK_PLK1_PLK1_ST	O15350	TP73	P53350	PLK1	S235	S235R	235	Missense	central	0	yes	11.099	0.000	EPSD	ICGC;COSMIC	10.919	Loss
Other_PLK_PLK1_PLK1_ST	O15350	TP73	P53350	PLK1	S235	G232S	232	Missense	distal	-3	no	11.099	10.326	EPSD	ICGC;COSMIC	10.919	Loss
Other_PLK_PLK1_PLK1_ST	O15350	TP73	P53350	PLK1	S235	P242L	242	Missense	distal	7	no	11.099	11.070	EPSD	ICGC;COSMIC	10.919	Down-regulation
Other_PLK_PLK1_PLK1_ST	Q9Y265	RUVBL1	P53350	PLK1	S19	R14S	14	Missense	distal	-5	no	11.064	10.380	EPSD	ICGC	10.919	Loss
Other_PLK_PLK1_PLK1_ST	Q9Y265	RUVBL1	P53350	PLK1	S19	L24M	24	Missense	distal	5	no	11.064	11.507	EPSD	ICGC	10.919	Up-regulation
Other_PLK_PLK1_PLK1_ST	Q9Y265	RUVBL1	P53350	PLK1	S29	L24M	24	Missense	distal	-5	no	13.246	12.646	EPSD	ICGC	10.919	Down-regulation
Other_PLK_PLK1_PLK1_ST	Q9Y265	RUVBL1	P53350	PLK1	S29	D27E	27	Missense	proximal	-2	no	13.246	12.852	EPSD	ICGC	10.919	Down-regulation
Other_PLK_PLK1_PLK1_ST	Q9Y265	RUVBL1	P53350	PLK1	T239	L243F	243	Missense	distal	4	no	16.439	16.237	PhosphoSitePlus	ICGC;COSMIC	10.919	Down-regulation
Other_PLK_PLK1_PLK1_ST	Q00613	HSF1	P53350	PLK1	S216	P223L	223	Missense	distal	7	no	12.468	12.439	PhosphoSitePlus	ICGC	10.919	Down-regulation
Other_PLK_PLK1_PLK1_ST	Q00613	HSF1	P53350	PLK1	S216	M212V	212	Missense	distal	-4	no	12.468	12.643	PhosphoSitePlus	ICGC	10.919	Up-regulation
Other_PLK_PLK1_PLK1_ST	Q00613	HSF1	P53350	PLK1	S221	P223L	223	Missense	proximal	2	no	11.236	12.784	EPSD	ICGC	10.919	Up-regulation
Other_PLK_PLK1_PLK1_ST	P36507	MAP2K2	P53350	PLK1	T17	A19T	19	Missense	proximal	2	no	10.988	10.587	EPSD	ICGC;COSMIC	10.919	Loss
Other_PLK_PLK1_PLK1_ST	P36507	MAP2K2	P53350	PLK1	S226	R231C	231	Missense	distal	5	no	14.657	14.441	PhosphoSitePlus;EPSD	ICGC;COSMIC	10.919	Down-regulation
Other_PLK_PLK1_PLK1_ST	P30626	SRI	P53350	PLK1	S87	M90V	90	Missense	distal	3	no	12.711	13.152	EPSD	ICGC	10.919	Up-regulation
Other_PLK_PLK1_PLK1_ST	P30626	SRI	P53350	PLK1	S149	T155S	155	Missense	distal	6	no	11.805	11.530	EPSD	ICGC;COSMIC	10.919	Down-regulation
Other_PLK_PLK1_PLK1_ST	Q07817	BCL2L1	P53350	PLK1	S62	P63T	63	Missense	proximal	1	no	12.434	11.905	PhosphoSitePlus	ICGC	10.919	Down-regulation
Other_PLK_PLK1_PLK1_ST	P54274	TERF1	P53350	PLK1	T24	D22N	22	Missense	proximal	-2	no	11.790	10.547	EPSD	ICGC;COSMIC	10.919	Loss
Other_PLK_PLK1_PLK1_ST	P54274	TERF1	P53350	PLK1	T24	E26K	26	Missense	proximal	2	no	11.790	11.621	EPSD	ICGC	10.919	Down-regulation
Other_PLK_PLK1_PLK1_ST	P54274	TERF1	P53350	PLK1	T24	G18N	18	Missense	distal	-6	no	11.790	12.139	EPSD	ICGC	10.919	Up-regulation
Other_PLK_PLK1_PLK1_ST	P54274	TERF1	P53350	PLK1	T24	D17N	17	Missense	distal	-7	no	11.790	11.930	EPSD	ICGC;GDSC;CCLE	10.919	Up-regulation
Other_PLK_PLK1_PLK1_ST	P54274	TERF1	P53350	PLK1	T254	A260V	260	Missense	distal	6	no	14.874	14.699	EPSD	ICGC;COSMIC	10.919	Down-regulation
Other_PLK_PLK1_PLK1_ST	P54274	TERF1	P53350	PLK1	T311	L315V	315	Missense	distal	4	no	11.638	11.789	EPSD	ICGC	10.919	Up-regulation
Other_PLK_PLK1_PLK1_ST	P54274	TERF1	P53350	PLK1	T311	L315F	315	Missense	distal	4	no	11.638	11.437	EPSD	ICGC	10.919	Down-regulation
Other_PLK_PLK1_PLK1_ST	Q2NKX8	ERCC6L	P53350	PLK1	T797	Q800K	800	Missense	distal	3	no	11.540	11.442	EPSD	ICGC;COSMIC	10.919	Down-regulation
Other_PLK_PLK1_PLK1_ST	Q2NKX8	ERCC6L	P53350	PLK1	S835	S828F	828	Missense	distal	-7	no	12.949	12.491	EPSD	ICGC	10.919	Down-regulation
Other_PLK_PLK1_PLK1_ST	Q2NKX8	ERCC6L	P53350	PLK1	S980	E976D	976	Missense	distal	-4	no	12.651	12.467	EPSD	ICGC;COSMIC;GDSC;CCLE	10.919	Down-regulation
Other_PLK_PLK1_PLK1_ST	Q2NKX8	ERCC6L	P53350	PLK1	S1049	F1046L	1046	Missense	distal	-3	no	9.965	11.369	EPSD	ICGC;COSMIC	10.919	Gain
Other_PLK_PLK1_PLK1_ST	Q2NKX8	ERCC6L	P53350	PLK1	T1063	P1070Q	1070	Missense	distal	7	no	10.926	10.930	PhosphoSitePlus	ICGC;COSMIC	10.919	Up-regulation
Other_PLK_PLK1_PLK1_ST	Q2NKX8	ERCC6L	P53350	PLK1	S1069	F1074Y	1074	Missense	distal	5	no	11.480	11.229	EPSD	ICGC;COSMIC	10.919	Down-regulation
Other_PLK_PLK1_PLK1_ST	Q2NKX8	ERCC6L	P53350	PLK1	S1069	R1073W	1073	Missense	distal	4	no	11.480	12.019	EPSD	ICGC;COSMIC	10.919	Up-regulation
Other_PLK_PLK1_PLK1_ST	Q2NKX8	ERCC6L	P53350	PLK1	S1069	G1072A	1072	Missense	distal	3	no	11.480	11.301	EPSD	ICGC;COSMIC	10.919	Down-regulation
Other_PLK_PLK1_PLK1_ST	Q2NKX8	ERCC6L	P53350	PLK1	S1069	P1070Q	1070	Missense	proximal	1	no	11.480	11.173	EPSD	ICGC;COSMIC	10.919	Down-regulation
Other_PLK_PLK1_PLK1_ST	Q2NKX8	ERCC6L	P53350	PLK1	S1077	F1074Y	1074	Missense	distal	-3	no	11.362	12.460	EPSD	ICGC;COSMIC	10.919	Up-regulation
Other_PLK_PLK1_PLK1_ST	Q2NKX8	ERCC6L	P53350	PLK1	S1077	R1073W	1073	Missense	distal	-4	no	11.362	11.776	EPSD	ICGC;COSMIC	10.919	Up-regulation
Other_PLK_PLK1_PLK1_ST	Q2NKX8	ERCC6L	P53350	PLK1	S1077	G1072A	1072	Missense	distal	-5	no	11.362	11.246	EPSD	ICGC;COSMIC	10.919	Down-regulation
Other_PLK_PLK1_PLK1_ST	Q2NKX8	ERCC6L	P53350	PLK1	S1077	P1070Q	1070	Missense	distal	-7	no	11.362	11.475	EPSD	ICGC;COSMIC	10.919	Up-regulation
Other_PLK_PLK1_PLK1_ST	Q2NKX8	ERCC6L	P53350	PLK1	S1082	M1087I	1087	Missense	distal	5	no	10.800	11.001	EPSD	ICGC;COSMIC	10.919	Gain
Other_PLK_PLK1_PLK1_ST	Q2NKX8	ERCC6L	P53350	PLK1	S1086	K1085T	1085	Missense	proximal	-1	no	12.621	12.449	EPSD	ICGC;COSMIC	10.919	Down-regulation
Other_PLK_PLK1_PLK1_ST	Q2NKX8	ERCC6L	P53350	PLK1	S1086	R1090I	1090	Missense	distal	4	no	12.621	12.375	EPSD	ICGC;COSMIC	10.919	Down-regulation
Other_PLK_PLK1_PLK1_ST	Q2NKX8	ERCC6L	P53350	PLK1	S1086	M1087I	1087	Missense	proximal	1	no	12.621	11.657	EPSD	ICGC;COSMIC	10.919	Down-regulation
Other_PLK_PLK1_PLK1_ST	Q2NKX8	ERCC6L	P53350	PLK1	S1117	L1114R	1114	Missense	distal	-3	no	11.840	11.898	EPSD	ICGC;COSMIC	10.919	Up-regulation
Other_PLK_PLK1_PLK1_ST	Q2NKX8	ERCC6L	P53350	PLK1	S1118	L1114R	1114	Missense	distal	-4	no	13.732	13.359	EPSD	ICGC;COSMIC	10.919	Down-regulation
Other_PLK_PLK1_PLK1_ST	Q2NKX8	ERCC6L	P53350	PLK1	S1134	P1127T	1127	Missense	distal	-7	no	11.020	11.221	EPSD	ICGC	10.919	Up-regulation
Other_PLK_PLK1_PLK1_ST	Q2NKX8	ERCC6L	P53350	PLK1	S1139	P1146S	1146	Missense	distal	7	no	11.843	11.816	EPSD	ICGC	10.919	Down-regulation
Other_PLK_PLK1_PLK1_ST	Q2NKX8	ERCC6L	P53350	PLK1	T1150	G1148R	1148	Missense	proximal	-2	no	10.758	11.202	EPSD	ICGC;COSMIC	10.919	Gain
Other_PLK_PLK1_PLK1_ST	Q99708	RBBP8	P53350	PLK1	T693	V699F	699	Missense	distal	6	no	11.614	10.931	PhosphoSitePlus	ICGC	10.919	Down-regulation
Other_PLK_PLK1_PLK1_ST	Q99708	RBBP8	P53350	PLK1	T693	T698I	698	Missense	distal	5	no	11.614	12.517	PhosphoSitePlus	ICGC	10.919	Up-regulation
Other_PLK_PLK1_PLK1_ST	Q99708	RBBP8	P53350	PLK1	T693	S696N	696	Missense	distal	3	no	11.614	11.660	PhosphoSitePlus	ICGC;COSMIC	10.919	Up-regulation
Other_PLK_PLK1_PLK1_ST	Q06609	RAD51	P53350	PLK1	S317	D316N	316	Missense	proximal	-1	no	12.576	11.643	EPSD	ICGC;COSMIC	10.919	Down-regulation
Other_PLK_PLK1_PLK1_ST	P46937	YAP1	P53350	PLK1	S94	P99Q	99	Missense	distal	5	no	11.592	10.754	EPSD	ICGC;COSMIC	10.919	Loss
Other_PLK_PLK1_PLK1_ST	P46937	YAP1	P53350	PLK1	S131	Q133L	133	Missense	proximal	2	no	11.213	11.687	EPSD	ICGC;COSMIC	10.919	Up-regulation
Other_PLK_PLK1_PLK1_ST	P46937	YAP1	P53350	PLK1	S131	V137F	137	Missense	distal	6	no	11.213	10.529	EPSD	ICGC;COSMIC	10.919	Loss
Other_PLK_PLK1_PLK1_ST	P46937	YAP1	P53350	PLK1	S131	L134F	134	Missense	distal	3	no	11.213	11.419	EPSD	ICGC;COSMIC	10.919	Up-regulation
Other_PLK_PLK1_PLK1_ST	P46937	YAP1	P53350	PLK1	S131	H126R	126	Missense	distal	-5	no	11.213	12.016	EPSD	ICGC;COSMIC	10.919	Up-regulation
Other_PLK_PLK1_PLK1_ST	P46937	YAP1	P53350	PLK1	S163	S164F	164	Missense	proximal	1	no	9.017	12.065	EPSD	ICGC	10.919	Gain
Other_PLK_PLK1_PLK1_ST	P46937	YAP1	P53350	PLK1	S164	D169N	169	Missense	distal	5	no	12.625	11.872	EPSD	ICGC;COSMIC	10.919	Down-regulation
Other_PLK_PLK1_PLK1_ST	P46937	YAP1	P53350	PLK1	S164	S163F	163	Missense	proximal	-1	no	12.625	12.086	EPSD	ICGC;COSMIC	10.919	Down-regulation
Other_PLK_PLK1_PLK1_ST	P46937	YAP1	P53350	PLK1	S164	V171A	171	Missense	distal	7	no	12.625	12.602	EPSD	ICGC;COSMIC	10.919	Down-regulation
Other_PLK_PLK1_PLK1_ST	P46937	YAP1	P53350	PLK1	S164	R161L	161	Missense	distal	-3	no	12.625	12.567	EPSD	ICGC	10.919	Down-regulation
Other_PLK_PLK1_PLK1_ST	P46937	YAP1	P53350	PLK1	S164	S164F	164	Missense	central	0	yes	12.625	0.000	EPSD	ICGC	10.919	Loss
Other_PLK_PLK1_PLK1_ST	P46937	YAP1	P53350	PLK1	S184	S184F	184	Missense	central	0	yes	11.085	0.000	EPSD	ICGC;COSMIC	10.919	Loss
Other_PLK_PLK1_PLK1_ST	P46937	YAP1	P53350	PLK1	S336	R331W	331	Missense	distal	-5	no	12.334	12.101	EPSD	ICGC;COSMIC	10.919	Down-regulation
Other_PLK_PLK1_PLK1_ST	P46937	YAP1	P53350	PLK1	S367	Q372R	372	Missense	distal	5	no	10.144	10.940	EPSD	ICGC;COSMIC	10.919	Gain
Other_PLK_PLK1_PLK1_ST	P46937	YAP1	P53350	PLK1	S367	G369W	369	Missense	proximal	2	no	10.144	11.743	EPSD	ICGC;COSMIC	10.919	Gain
Other_PLK_PLK1_PLK1_ST	P46937	YAP1	P53350	PLK1	S393	R394Q	394	Missense	proximal	1	no	11.794	13.773	EPSD	ICGC;COSMIC	10.919	Up-regulation
Other_PLK_PLK1_PLK1_ST	P46937	YAP1	P53350	PLK1	S393	S397I	397	Missense	distal	4	no	11.794	10.603	EPSD	ICGC	10.919	Loss
Other_PLK_PLK1_PLK1_ST	P46937	YAP1	P53350	PLK1	S393	H392N	392	Missense	proximal	-1	no	11.794	11.593	EPSD	ICGC;COSMIC	10.919	Down-regulation
Other_PLK_PLK1_PLK1_ST	P46937	YAP1	P53350	PLK1	S393	T398A	398	Missense	distal	5	no	11.794	12.966	EPSD	ICGC;COSMIC	10.919	Up-regulation
Other_PLK_PLK1_PLK1_ST	P46937	YAP1	P53350	PLK1	S397	L402P	402	Missense	distal	5	no	13.138	13.871	EPSD	ICGC;COSMIC	10.919	Up-regulation
Other_PLK_PLK1_PLK1_ST	P46937	YAP1	P53350	PLK1	S397	R394Q	394	Missense	distal	-3	no	13.138	12.463	EPSD	ICGC;COSMIC	10.919	Down-regulation
Other_PLK_PLK1_PLK1_ST	P46937	YAP1	P53350	PLK1	S397	S397I	397	Missense	central	0	yes	13.138	0.000	EPSD	ICGC	10.919	Loss
Other_PLK_PLK1_PLK1_ST	P46937	YAP1	P53350	PLK1	S397	H392N	392	Missense	distal	-5	no	13.138	13.204	EPSD	ICGC;COSMIC	10.919	Up-regulation
Other_PLK_PLK1_PLK1_ST	P46937	YAP1	P53350	PLK1	S397	T398A	398	Missense	proximal	1	no	13.138	12.675	EPSD	ICGC;COSMIC	10.919	Down-regulation
Other_PLK_PLK1_PLK1_ST	P46937	YAP1	P53350	PLK1	S400	R394Q	394	Missense	distal	-6	no	10.616	11.063	EPSD	ICGC;COSMIC	10.919	Gain
Other_PLK_PLK1_PLK1_ST	P46937	YAP1	P53350	PLK1	S400	S397I	397	Missense	distal	-3	no	10.616	11.015	EPSD	ICGC	10.919	Gain
Other_PLK_PLK1_PLK1_ST	P46937	YAP1	P53350	PLK1	S400	T398A	398	Missense	proximal	-2	no	10.616	11.235	EPSD	ICGC;COSMIC	10.919	Gain
Other_PLK_PLK1_PLK1_ST	P46937	YAP1	P53350	PLK1	S403	L402P	402	Missense	proximal	-1	no	13.822	13.107	EPSD	ICGC;COSMIC	10.919	Down-regulation
Other_PLK_PLK1_PLK1_ST	P46937	YAP1	P53350	PLK1	S403	V409F	409	Missense	distal	6	no	13.822	13.138	EPSD	ICGC	10.919	Down-regulation
Other_PLK_PLK1_PLK1_ST	P46937	YAP1	P53350	PLK1	S403	S397I	397	Missense	distal	-6	no	13.822	13.890	EPSD	ICGC	10.919	Up-regulation
Other_PLK_PLK1_PLK1_ST	P46937	YAP1	P53350	PLK1	S403	T398A	398	Missense	distal	-5	no	13.822	13.891	EPSD	ICGC;COSMIC	10.919	Up-regulation
Other_PLK_PLK1_PLK1_ST	P46937	YAP1	P53350	PLK1	S499	T493A	493	Missense	distal	-6	no	11.760	11.827	EPSD	ICGC;COSMIC	10.919	Up-regulation
Other_PLK_PLK1_PLK1_ST	Q8IWB6	TEX14	P53350	PLK1	S1385	S1384T	1384	Missense	proximal	-1	no	14.815	14.067	EPSD	ICGC	10.919	Down-regulation
Other_PLK_PLK1_PLK1_ST	Q96T23	RSF1	P53350	PLK1	S218	S223F	223	Missense	distal	5	no	13.636	13.730	EPSD	ICGC;COSMIC	10.919	Up-regulation
Other_PLK_PLK1_PLK1_ST	Q96T23	RSF1	P53350	PLK1	S218	S223P	223	Missense	distal	5	no	13.636	14.023	EPSD	ICGC;COSMIC	10.919	Up-regulation
Other_PLK_PLK1_PLK1_ST	Q96T23	RSF1	P53350	PLK1	S227	S223F	223	Missense	distal	-4	no	11.257	10.939	EPSD	ICGC;COSMIC	10.919	Down-regulation
Other_PLK_PLK1_PLK1_ST	Q96T23	RSF1	P53350	PLK1	S227	S223P	223	Missense	distal	-4	no	11.257	11.135	EPSD	ICGC;COSMIC	10.919	Down-regulation
Other_PLK_PLK1_PLK1_ST	Q8TD19	NEK9	P53350	PLK1	S29	P32T	32	Missense	distal	3	no	11.670	11.512	EPSD	ICGC	10.919	Down-regulation
Other_PLK_PLK1_PLK1_ST	Q8TD19	NEK9	P53350	PLK1	S29	G31E	31	Missense	proximal	2	no	11.670	12.659	EPSD	ICGC	10.919	Up-regulation
Other_PLK_PLK1_PLK1_ST	Q8TD19	NEK9	P53350	PLK1	T67	L68Q	68	Missense	proximal	1	no	11.239	10.086	EPSD	ICGC;COSMIC	10.919	Loss
Other_PLK_PLK1_PLK1_ST	Q8TD19	NEK9	P53350	PLK1	T67	R70H	70	Missense	distal	3	no	11.239	11.370	EPSD	ICGC	10.919	Up-regulation
Other_PLK_PLK1_PLK1_ST	Q8TD19	NEK9	P53350	PLK1	T67	L68P	68	Missense	proximal	1	no	11.239	10.393	EPSD	ICGC;COSMIC	10.919	Loss
Other_PLK_PLK1_PLK1_ST	Q8TD19	NEK9	P53350	PLK1	S76	R70H	70	Missense	distal	-6	no	12.438	12.897	EPSD	ICGC	10.919	Up-regulation
Other_PLK_PLK1_PLK1_ST	Q8TD19	NEK9	P53350	PLK1	S206	A208D	208	Missense	proximal	2	no	13.924	14.163	EPSD	ICGC;COSMIC	10.919	Up-regulation
Other_PLK_PLK1_PLK1_ST	Q8TD19	NEK9	P53350	PLK1	T210	A208D	208	Missense	proximal	-2	no	9.815	12.387	PhosphoSitePlus	ICGC;COSMIC	10.919	Gain
Other_PLK_PLK1_PLK1_ST	Q8TD19	NEK9	P53350	PLK1	T250	R249M	249	Missense	proximal	-1	no	10.711	11.719	EPSD	ICGC;COSMIC	10.919	Gain
Other_PLK_PLK1_PLK1_ST	Q8TD19	NEK9	P53350	PLK1	S966	K959N	959	Missense	distal	-7	no	12.166	12.321	EPSD	ICGC	10.919	Up-regulation
Other_PLK_PLK1_PLK1_ST	Q13416	ORC2	P53350	PLK1	S96	Q98H	98	Missense	proximal	2	no	11.345	11.723	EPSD	ICGC;COSMIC	10.919	Up-regulation
Other_PLK_PLK1_PLK1_ST	Q13416	ORC2	P53350	PLK1	S96	R100I	100	Missense	distal	4	no	11.345	11.098	EPSD	ICGC;COSMIC	10.919	Down-regulation
Other_PLK_PLK1_PLK1_ST	Q13416	ORC2	P53350	PLK1	S124	P117S	117	Missense	distal	-7	no	12.397	12.607	EPSD	ICGC	10.919	Up-regulation
Other_PLK_PLK1_PLK1_ST	Q13416	ORC2	P53350	PLK1	T132	V135G	135	Missense	distal	3	no	12.926	12.777	EPSD	ICGC	10.919	Down-regulation
Other_PLK_PLK1_PLK1_ST	Q13416	ORC2	P53350	PLK1	T132	T132M	132	Missense	central	0	yes	12.926	0.000	EPSD	ICGC	10.919	Loss
Other_PLK_PLK1_PLK1_ST	Q13416	ORC2	P53350	PLK1	S156	D154G	154	Missense	proximal	-2	no	13.391	10.069	EPSD	ICGC;COSMIC	10.919	Loss
Other_PLK_PLK1_PLK1_ST	Q13416	ORC2	P53350	PLK1	S156	D154E	154	Missense	proximal	-2	no	13.391	12.997	EPSD	ICGC	10.919	Down-regulation
Other_PLK_PLK1_PLK1_ST	Q13416	ORC2	P53350	PLK1	S156	P163T	163	Missense	distal	7	no	13.391	13.349	EPSD	ICGC	10.919	Down-regulation
Other_PLK_PLK1_PLK1_ST	Q13416	ORC2	P53350	PLK1	S156	A162S	162	Missense	distal	6	no	13.391	13.107	EPSD	ICGC	10.919	Down-regulation
Other_PLK_PLK1_PLK1_ST	Q13416	ORC2	P53350	PLK1	S156	D154Y	154	Missense	proximal	-2	no	13.391	11.849	EPSD	ICGC;COSMIC	10.919	Down-regulation
Other_PLK_PLK1_PLK1_ST	Q13416	ORC2	P53350	PLK1	S177	D178E	178	Missense	proximal	1	no	11.229	10.985	EPSD	ICGC	10.919	Down-regulation
Other_PLK_PLK1_PLK1_ST	Q13416	ORC2	P53350	PLK1	S177	S181G	181	Missense	distal	4	no	11.229	11.144	EPSD	ICGC	10.919	Down-regulation
Other_PLK_PLK1_PLK1_ST	Q13416	ORC2	P53350	PLK1	S179	D178E	178	Missense	proximal	-1	no	11.399	10.602	EPSD	ICGC	10.919	Loss
Other_PLK_PLK1_PLK1_ST	Q13416	ORC2	P53350	PLK1	S179	S181G	181	Missense	proximal	2	no	11.399	9.818	EPSD	ICGC	10.919	Loss
Other_PLK_PLK1_PLK1_ST	Q13416	ORC2	P53350	PLK1	S188	S188L	188	Missense	central	0	yes	12.626	0.000	PhosphoSitePlus	ICGC;COSMIC	10.919	Loss
Other_PLK_PLK1_PLK1_ST	Q13416	ORC2	P53350	PLK1	S188	S181G	181	Missense	distal	-7	no	12.626	11.930	PhosphoSitePlus	ICGC	10.919	Down-regulation
Other_PLK_PLK1_PLK1_ST	Q13416	ORC2	P53350	PLK1	T202	N203D	203	Missense	proximal	1	no	11.605	11.800	EPSD	ICGC	10.919	Up-regulation
Other_PLK_PLK1_PLK1_ST	Q13416	ORC2	P53350	PLK1	T258	R257S	257	Missense	proximal	-1	no	10.417	11.354	EPSD	ICGC;COSMIC	10.919	Gain
Other_PLK_PLK1_PLK1_ST	Q13416	ORC2	P53350	PLK1	S282	L287I	287	Missense	distal	5	no	10.314	10.958	EPSD	ICGC	10.919	Gain
CMGC_CDK_CDK8_CDK19_ST	P46531	NOTCH1	Q9BWU1	CDK19	S1941	L1948M	1948	Missense	distal	7	no	3.600	3.582	EPSD	ICGC;COSMIC	1.856	Down-regulation
CMGC_CDK_CDK8_CDK19_ST	P46531	NOTCH1	Q9BWU1	CDK19	T1997	G1995V	1995	Missense	proximal	-2	no	1.759	1.860	EPSD	ICGC;COSMIC	1.856	Gain
CMGC_CDK_CDK8_CDK19_ST	P46531	NOTCH1	Q9BWU1	CDK19	T2090	R2087L	2087	Missense	distal	-3	no	1.816	2.033	EPSD	ICGC;COSMIC	1.856	Gain
CMGC_CDK_CDK8_CDK19_ST	P46531	NOTCH1	Q9BWU1	CDK19	T2132	H2125Q	2125	Missense	distal	-7	no	2.184	2.166	EPSD	ICGC;GDSC;CCLE	1.856	Down-regulation
CMGC_CDK_CDK8_CDK19_ST	P46531	NOTCH1	Q9BWU1	CDK19	T2132	G2126R	2126	Missense	distal	-6	no	2.184	2.172	EPSD	ICGC	1.856	Down-regulation
CMGC_CDK_CDK8_CDK19_ST	P46531	NOTCH1	Q9BWU1	CDK19	T2132	G2130W	2130	Missense	proximal	-2	no	2.184	2.165	EPSD	ICGC;COSMIC	1.856	Down-regulation
CMGC_CDK_CDK8_CDK19_ST	P46531	NOTCH1	Q9BWU1	CDK19	T2132	P2138Q	2138	Missense	distal	6	no	2.184	2.337	EPSD	ICGC;COSMIC	1.856	Up-regulation
CMGC_CDK_CDK8_CDK19_ST	O00303	EIF3F	Q9BWU1	CDK19	T119	D125V	125	Missense	distal	6	no	8.414	8.081	EPSD;PhosphoSitePlus	ICGC;COSMIC	1.856	Down-regulation
CMGC_CDK_CDK8_CDK19_ST	O00303	EIF3F	Q9BWU1	CDK19	T119	D125G	125	Missense	distal	6	no	8.414	8.388	EPSD;PhosphoSitePlus	ICGC	1.856	Down-regulation
CMGC_CDK_CDK8_CDK19_ST	O00303	EIF3F	Q9BWU1	CDK19	T119	L121F	121	Missense	proximal	2	no	8.414	8.431	EPSD;PhosphoSitePlus	ICGC;COSMIC	1.856	Up-regulation
CMGC_CDK_CDK8_CDK19_ST	O00303	EIF3F	Q9BWU1	CDK19	T119	A113T	113	Missense	distal	-6	no	8.414	7.948	EPSD;PhosphoSitePlus	ICGC;COSMIC	1.856	Down-regulation
CMGC_CDK_CDK8_CDK19_ST	Q13153	PAK1	Q9BWU1	CDK19	T109	T113I	113	Missense	distal	4	no	4.084	4.119	EPSD	ICGC;COSMIC	1.856	Up-regulation
CMGC_CDK_CDK8_CDK19_ST	Q13153	PAK1	Q9BWU1	CDK19	T109	I112T	112	Missense	distal	3	no	4.084	4.054	EPSD	ICGC;COSMIC	1.856	Down-regulation
CMGC_CDK_CDK8_CDK19_ST	Q13153	PAK1	Q9BWU1	CDK19	T109	I112V	112	Missense	distal	3	no	4.084	4.075	EPSD	ICGC;COSMIC	1.856	Down-regulation
CMGC_CDK_CDK8_CDK19_ST	Q13153	PAK1	Q9BWU1	CDK19	S155	K162R	162	Missense	distal	7	no	3.249	3.152	EPSD	ICGC;COSMIC	1.856	Down-regulation
CMGC_CDK_CDK8_CDK19_ST	Q13153	PAK1	Q9BWU1	CDK19	S223	T230A	230	Missense	distal	7	no	1.964	1.768	EPSD	ICGC;COSMIC	1.856	Loss
CMGC_CDK_CDK8_CDK19_ST	Q13153	PAK1	Q9BWU1	CDK19	S223	T219K	219	Missense	distal	-4	no	1.964	2.153	EPSD	ICGC;CCLE	1.856	Up-regulation
CMGC_CDK_CDK8_CDK19_ST	Q13153	PAK1	Q9BWU1	CDK19	T230	T230A	230	Missense	central	0	yes	2.461	0.000	EPSD	ICGC;COSMIC	1.856	Loss
CMGC_CDK_CDK8_CDK19_ST	Q13153	PAK1	Q9BWU1	CDK19	T230	P231T	231	Missense	proximal	1	no	2.461	2.539	EPSD	ICGC	1.856	Up-regulation
CMGC_CDK_CDK8_CDK19_ST	Q13153	PAK1	Q9BWU1	CDK19	T239	T239I	239	Missense	central	0	yes	2.761	0.000	EPSD	ICGC;COSMIC	1.856	Loss
CMGC_CDK_CDK8_CDK19_ST	Q13153	PAK1	Q9BWU1	CDK19	T239	Q242K	242	Missense	distal	3	no	2.761	2.784	EPSD	ICGC	1.856	Up-regulation
CMGC_CDK_CDK8_CDK19_ST	Q13153	PAK1	Q9BWU1	CDK19	S529	P532L	532	Missense	distal	3	no	1.969	2.209	EPSD	ICGC;COSMIC	1.856	Up-regulation
CMGC_CDK_CDK5_CDK5_ST	O60331	PIP5K1C	Q00535	CDK5	S453	S449Y	449	Missense	distal	-4	no	20.931	19.950	PhosphoSitePlus;EPSD	ICGC	8.808	Down-regulation
CMGC_CDK_CDK5_CDK5_ST	O60331	PIP5K1C	Q00535	CDK5	S453	G458W	458	Missense	distal	5	no	20.931	20.921	PhosphoSitePlus;EPSD	ICGC;COSMIC	8.808	Down-regulation
CMGC_CDK_CDK5_CDK5_ST	O60331	PIP5K1C	Q00535	CDK5	S453	S455P	455	Missense	proximal	2	no	20.931	20.949	PhosphoSitePlus;EPSD	ICGC;COSMIC	8.808	Up-regulation
CMGC_CDK_CDK5_CDK5_ST	O60331	PIP5K1C	Q00535	CDK5	S539	P536H	536	Missense	distal	-3	no	17.824	17.802	EPSD	ICGC	8.808	Down-regulation
CMGC_CDK_CDK5_CDK5_ST	O60331	PIP5K1C	Q00535	CDK5	S539	S544L	544	Missense	distal	5	no	17.824	17.639	EPSD	ICGC;COSMIC	8.808	Down-regulation
CMGC_CDK_CDK5_CDK5_ST	O60331	PIP5K1C	Q00535	CDK5	S650	W647L	647	Missense	distal	-3	no	19.519	19.502	EPSD;PhosphoSitePlus	ICGC;COSMIC	8.808	Down-regulation
CMGC_CDK_CDK5_CDK5_ST	O60331	PIP5K1C	Q00535	CDK5	S650	R645M	645	Missense	distal	-5	no	19.519	19.156	EPSD;PhosphoSitePlus	ICGC;COSMIC	8.808	Down-regulation
CMGC_CDK_CDK5_CDK5_ST	O60331	PIP5K1C	Q00535	CDK5	S650	R645G	645	Missense	distal	-5	no	19.519	19.267	EPSD;PhosphoSitePlus	ICGC;COSMIC;CCLE	8.808	Down-regulation
CMGC_CDK_CDK5_CDK5_ST	Q07820	MCL1	Q00535	CDK5	T92	V86L	86	Missense	distal	-6	no	18.506	18.429	PhosphoSitePlus	ICGC	8.808	Down-regulation
CMGC_CDK_CDK5_CDK5_ST	Q07820	MCL1	Q00535	CDK5	T92	E85D	85	Missense	distal	-7	no	18.506	18.508	PhosphoSitePlus	ICGC	8.808	Up-regulation
CMGC_CDK_CDK5_CDK5_ST	Q07820	MCL1	Q00535	CDK5	T92	A94T	94	Missense	proximal	2	no	18.506	18.625	PhosphoSitePlus	ICGC	8.808	Up-regulation
CMGC_CDK_CDK5_CDK5_ST	Q07820	MCL1	Q00535	CDK5	T92	R95S	95	Missense	distal	3	no	18.506	17.088	PhosphoSitePlus	ICGC;COSMIC	8.808	Down-regulation
CMGC_CDK_CDK5_CDK5_ST	Q07820	MCL1	Q00535	CDK5	T92	T92P	92	Missense	central	0	yes	18.506	0.000	PhosphoSitePlus	ICGC;COSMIC	8.808	Loss
CMGC_CDK_CDK5_CDK5_ST	Q07820	MCL1	Q00535	CDK5	S121	I119V	119	Missense	proximal	-2	no	17.010	17.151	EPSD	ICGC;COSMIC	8.808	Up-regulation
CMGC_CDK_CDK5_CDK5_ST	Q07820	MCL1	Q00535	CDK5	S121	E125D	125	Missense	distal	4	no	17.010	17.002	EPSD	ICGC;COSMIC	8.808	Down-regulation
CMGC_CDK_CDK5_CDK5_ST	Q07820	MCL1	Q00535	CDK5	T163	T156A	156	Missense	distal	-7	no	18.116	18.077	EPSD	ICGC	8.808	Down-regulation
CMGC_CDK_CDK5_CDK5_ST	Q07820	MCL1	Q00535	CDK5	T163	P161S	161	Missense	proximal	-2	no	18.116	18.017	EPSD	ICGC;COSMIC	8.808	Down-regulation
CMGC_CDK_CDK5_CDK5_ST	Q07820	MCL1	Q00535	CDK5	T163	P166Q	166	Missense	distal	3	no	18.116	17.712	EPSD	ICGC;COSMIC	8.808	Down-regulation
CMGC_CDK_CDK5_CDK5_ST	Q07820	MCL1	Q00535	CDK5	T205	S206R	206	Missense	proximal	1	no	6.853	9.807	EPSD	ICGC	8.808	Gain
CMGC_CDK_CDK5_CDK5_ST	Q07820	MCL1	Q00535	CDK5	S206	M199K	199	Missense	distal	-7	no	9.433	9.523	EPSD	ICGC	8.808	Up-regulation
CMGC_CDK_CDK5_CDK5_ST	Q07820	MCL1	Q00535	CDK5	S206	S206R	206	Missense	central	0	yes	9.433	0.000	EPSD	ICGC	8.808	Loss
CMGC_CDK_CDK5_CDK5_ST	Q07820	MCL1	Q00535	CDK5	S247	M250I	250	Missense	distal	3	no	8.430	8.950	EPSD	ICGC;COSMIC	8.808	Gain
CMGC_CDK_CDK5_CDK5_ST	P49023	PXN	Q00535	CDK5	S230	S226T	226	Missense	distal	-4	no	17.745	17.243	EPSD	ICGC;COSMIC	8.808	Down-regulation
CMGC_CDK_CDK5_CDK5_ST	P49023	PXN	Q00535	CDK5	S322	S322L	322	Missense	central	0	yes	17.843	0.000	EPSD	ICGC;COSMIC	8.808	Loss
CMGC_CDK_CDK5_CDK5_ST	P49023	PXN	Q00535	CDK5	S322	P328L	328	Missense	distal	6	no	17.843	17.829	EPSD	ICGC	8.808	Down-regulation
CMGC_CDK_CDK5_CDK5_ST	P10636	MAPT	Q00535	CDK5	T111	D116E	116	Missense	distal	5	no	15.796	15.817	EPSD	ICGC;COSMIC	8.808	Up-regulation
CMGC_CDK_CDK5_CDK5_ST	P10636	MAPT	Q00535	CDK5	S228	P233H	233	Missense	distal	5	no	17.027	16.999	EPSD	ICGC;COSMIC	8.808	Down-regulation
CMGC_CDK_CDK5_CDK5_ST	P10636	MAPT	Q00535	CDK5	S228	S232F	232	Missense	distal	4	no	17.027	16.915	EPSD	ICGC	8.808	Down-regulation
CMGC_CDK_CDK5_CDK5_ST	P10636	MAPT	Q00535	CDK5	S228	D225N	225	Missense	distal	-3	no	17.027	17.050	EPSD	ICGC	8.808	Up-regulation
CMGC_CDK_CDK5_CDK5_ST	P10636	MAPT	Q00535	CDK5	S228	V224I	224	Missense	distal	-4	no	17.027	16.894	EPSD	ICGC;COSMIC	8.808	Down-regulation
CMGC_CDK_CDK5_CDK5_ST	P10636	MAPT	Q00535	CDK5	S232	P233H	233	Missense	proximal	1	no	18.084	-0.428	EPSD	ICGC;COSMIC	8.808	Loss
CMGC_CDK_CDK5_CDK5_ST	P10636	MAPT	Q00535	CDK5	S232	S232F	232	Missense	central	0	yes	18.084	0.000	EPSD	ICGC	8.808	Loss
CMGC_CDK_CDK5_CDK5_ST	P10636	MAPT	Q00535	CDK5	S232	D225N	225	Missense	distal	-7	no	18.084	18.102	EPSD	ICGC	8.808	Up-regulation
CMGC_CDK_CDK5_CDK5_ST	P10636	MAPT	Q00535	CDK5	S232	P239Q	239	Missense	distal	7	no	18.084	18.080	EPSD	ICGC;COSMIC	8.808	Down-regulation
CMGC_CDK_CDK5_CDK5_ST	P10636	MAPT	Q00535	CDK5	S238	P233H	233	Missense	distal	-5	no	18.116	18.047	EPSD	ICGC;COSMIC	8.808	Down-regulation
CMGC_CDK_CDK5_CDK5_ST	P10636	MAPT	Q00535	CDK5	S238	S232F	232	Missense	distal	-6	no	18.116	17.943	EPSD	ICGC	8.808	Down-regulation
CMGC_CDK_CDK5_CDK5_ST	P10636	MAPT	Q00535	CDK5	S238	P239Q	239	Missense	proximal	1	no	18.116	9.141	EPSD	ICGC;COSMIC	8.808	Down-regulation
CMGC_CDK_CDK5_CDK5_ST	P10636	MAPT	Q00535	CDK5	S428	S427F	427	Missense	proximal	-1	no	17.304	17.295	EPSD	ICGC	8.808	Down-regulation
CMGC_CDK_CDK5_CDK5_ST	P10636	MAPT	Q00535	CDK5	S438	Y441H	441	Missense	distal	3	no	17.434	18.602	EPSD	ICGC;COSMIC	8.808	Up-regulation
CMGC_CDK_CDK5_CDK5_ST	P10636	MAPT	Q00535	CDK5	S447	Y441H	441	Missense	distal	-6	no	9.502	9.576	EPSD	ICGC;COSMIC	8.808	Up-regulation
CMGC_CDK_CDK5_CDK5_ST	P10636	MAPT	Q00535	CDK5	S516	G521R	521	Missense	distal	5	no	17.498	17.664	EPSD	ICGC;COSMIC	8.808	Up-regulation
CMGC_CDK_CDK5_CDK5_ST	P10636	MAPT	Q00535	CDK5	S519	G521R	521	Missense	proximal	2	no	17.944	18.116	EPSD	ICGC;COSMIC	8.808	Up-regulation
CMGC_CDK_CDK5_CDK5_ST	P10636	MAPT	Q00535	CDK5	T522	G521R	521	Missense	proximal	-1	no	16.384	16.389	EPSD	ICGC;COSMIC	8.808	Up-regulation
CMGC_CDK_CDK5_CDK5_ST	P10636	MAPT	Q00535	CDK5	S525	G521R	521	Missense	distal	-4	no	9.794	10.173	EPSD	ICGC;COSMIC	8.808	Up-regulation
CMGC_CDK_CDK5_CDK5_ST	P42858	HTT	Q00535	CDK5	S263	R268W	268	Missense	distal	5	no	17.729	17.552	EPSD	ICGC;COSMIC	8.808	Down-regulation
CMGC_CDK_CDK5_CDK5_ST	P42858	HTT	Q00535	CDK5	S263	R268Q	268	Missense	distal	5	no	17.729	17.604	EPSD	ICGC;COSMIC;CCLE	8.808	Down-regulation
CMGC_CDK_CDK5_CDK5_ST	P42858	HTT	Q00535	CDK5	S263	S262I	262	Missense	proximal	-1	no	17.729	17.725	EPSD	ICGC	8.808	Down-regulation
CMGC_CDK_CDK5_CDK5_ST	P42858	HTT	Q00535	CDK5	S432	C431F	431	Missense	proximal	-1	no	16.584	16.582	EPSD;PhosphoSitePlus	ICGC;COSMIC	8.808	Down-regulation
CMGC_CDK_CDK5_CDK5_ST	P42858	HTT	Q00535	CDK5	T486	D493G	493	Missense	distal	7	no	17.017	17.016	EPSD	ICGC;COSMIC	8.808	Down-regulation
CMGC_CDK_CDK5_CDK5_ST	P42858	HTT	Q00535	CDK5	S643	P639S	639	Missense	distal	-4	no	9.018	9.364	EPSD	ICGC;COSMIC	8.808	Up-regulation
CMGC_CDK_CDK5_CDK5_ST	P42858	HTT	Q00535	CDK5	S781	V787M	787	Missense	distal	6	no	9.806	9.792	EPSD	ICGC;COSMIC;GDSC	8.808	Down-regulation
CMGC_CDK_CDK5_CDK5_ST	P42858	HTT	Q00535	CDK5	S1179	R1183Q	1183	Missense	distal	4	no	19.777	19.731	EPSD;PhosphoSitePlus	ICGC;COSMIC	8.808	Down-regulation
CMGC_CDK_CDK5_CDK5_ST	P42858	HTT	Q00535	CDK5	S1199	S1199I	1199	Missense	central	0	yes	20.034	0.000	PhosphoSitePlus;EPSD	ICGC	8.808	Loss
CMGC_CDK_CDK5_CDK5_ST	P42858	HTT	Q00535	CDK5	S1199	P1197L	1197	Missense	proximal	-2	no	20.034	19.619	PhosphoSitePlus;EPSD	ICGC;COSMIC	8.808	Down-regulation
CMGC_CDK_CDK5_CDK5_ST	P42858	HTT	Q00535	CDK5	S1259	Q1257R	1257	Missense	proximal	-2	no	8.680	8.817	EPSD	ICGC;COSMIC	8.808	Gain
CMGC_CDK_CDK5_CDK5_ST	P42858	HTT	Q00535	CDK5	S1870	E1876A	1876	Missense	distal	6	no	17.377	17.375	EPSD	ICGC	8.808	Down-regulation
CMGC_CDK_CDK5_CDK5_ST	P42858	HTT	Q00535	CDK5	S2072	S2074Y	2074	Missense	proximal	2	no	17.999	17.848	EPSD	ICGC;COSMIC	8.808	Down-regulation
CMGC_CDK_CDK5_CDK5_ST	P42858	HTT	Q00535	CDK5	S2072	S2072I	2072	Missense	central	0	yes	17.999	0.000	EPSD	ICGC	8.808	Loss
CMGC_CDK_CDK5_CDK5_ST	P42858	HTT	Q00535	CDK5	S2074	S2074Y	2074	Missense	central	0	yes	18.577	0.000	EPSD	ICGC;COSMIC	8.808	Loss
CMGC_CDK_CDK5_CDK5_ST	P42858	HTT	Q00535	CDK5	S2074	S2072I	2072	Missense	proximal	-2	no	18.577	18.354	EPSD	ICGC	8.808	Down-regulation
CMGC_CDK_CDK5_CDK5_ST	P42858	HTT	Q00535	CDK5	S2094	V2088L	2088	Missense	distal	-6	no	19.112	19.034	EPSD	ICGC;COSMIC	8.808	Down-regulation
CMGC_CDK_CDK5_CDK5_ST	P42858	HTT	Q00535	CDK5	S2094	V2101F	2101	Missense	distal	7	no	19.112	19.097	EPSD	ICGC;COSMIC	8.808	Down-regulation
CMGC_CDK_CDK5_CDK5_ST	P42858	HTT	Q00535	CDK5	S2328	Q2325H	2325	Missense	distal	-3	no	18.870	18.864	EPSD	ICGC;COSMIC	8.808	Down-regulation
CMGC_CDK_CDK5_CDK5_ST	P42858	HTT	Q00535	CDK5	S2421	W2420R	2420	Missense	proximal	-1	no	18.344	18.348	EPSD	ICGC;COSMIC	8.808	Up-regulation
CMGC_CDK_CDK5_CDK5_ST	P42858	HTT	Q00535	CDK5	S2651	P2656T	2656	Missense	distal	5	no	18.695	18.707	EPSD	ICGC;COSMIC	8.808	Up-regulation
CMGC_CDK_CDK5_CDK5_ST	P42858	HTT	Q00535	CDK5	S2655	P2656T	2656	Missense	proximal	1	no	18.601	8.114	EPSD	ICGC;COSMIC	8.808	Loss
CMGC_CDK_CDK5_CDK5_ST	P42858	HTT	Q00535	CDK5	S2659	R2663Q	2663	Missense	distal	4	no	10.320	10.274	EPSD	ICGC;COSMIC	8.808	Down-regulation
CMGC_CDK_CDK5_CDK5_ST	P42858	HTT	Q00535	CDK5	S2659	P2656T	2656	Missense	distal	-3	no	10.320	10.313	EPSD	ICGC;COSMIC	8.808	Down-regulation
CMGC_CDK_CDK5_CDK5_ST	P42858	HTT	Q00535	CDK5	S2812	A2818S	2818	Missense	distal	6	no	10.851	10.863	EPSD	ICGC;COSMIC	8.808	Up-regulation
CMGC_CDK_CDK5_CDK5_ST	P42858	HTT	Q00535	CDK5	S2812	A2818T	2818	Missense	distal	6	no	10.851	10.864	EPSD	ICGC;COSMIC	8.808	Up-regulation
CMGC_CDK_CDK5_CDK5_ST	P42858	HTT	Q00535	CDK5	S2812	D2808N	2808	Missense	distal	-4	no	10.851	11.015	EPSD	ICGC;COSMIC	8.808	Up-regulation
CMGC_CDK_CDK5_CDK5_ST	P42858	HTT	Q00535	CDK5	S2934	T2938S	2938	Missense	distal	4	no	19.397	19.400	EPSD	ICGC	8.808	Up-regulation
CMGC_CDK_CDK5_CDK5_ST	P04150	NR3C1	Q00535	CDK5	T8	E13Q	13	Missense	distal	5	no	20.388	20.439	EPSD	ICGC;COSMIC	8.808	Up-regulation
CMGC_CDK_CDK5_CDK5_ST	P04150	NR3C1	Q00535	CDK5	T8	S3F	3	Missense	distal	-5	no	20.388	20.058	EPSD	ICGC	8.808	Down-regulation
CMGC_CDK_CDK5_CDK5_ST	P04150	NR3C1	Q00535	CDK5	S45	A49D	49	Missense	distal	4	no	16.971	16.972	EPSD	ICGC	8.808	Up-regulation
CMGC_CDK_CDK5_CDK5_ST	P04150	NR3C1	Q00535	CDK5	S52	R59L	59	Missense	distal	7	no	8.918	8.904	EPSD	ICGC;COSMIC	8.808	Down-regulation
CMGC_CDK_CDK5_CDK5_ST	P04150	NR3C1	Q00535	CDK5	S52	A49D	49	Missense	distal	-3	no	8.918	8.925	EPSD	ICGC	8.808	Up-regulation
CMGC_CDK_CDK5_CDK5_ST	P04150	NR3C1	Q00535	CDK5	S54	L61P	61	Missense	distal	7	no	9.403	9.415	EPSD	ICGC;COSMIC	8.808	Up-regulation
CMGC_CDK_CDK5_CDK5_ST	P04150	NR3C1	Q00535	CDK5	S54	R59L	59	Missense	distal	5	no	9.403	9.155	EPSD	ICGC;COSMIC	8.808	Down-regulation
CMGC_CDK_CDK5_CDK5_ST	P04150	NR3C1	Q00535	CDK5	S54	A49D	49	Missense	distal	-5	no	9.403	9.419	EPSD	ICGC	8.808	Up-regulation
CMGC_CDK_CDK5_CDK5_ST	P04150	NR3C1	Q00535	CDK5	S226	E221K	221	Missense	distal	-5	no	16.746	17.036	EPSD;PhosphoSitePlus	ICGC;COSMIC	8.808	Up-regulation
CMGC_CDK_CDK5_CDK5_ST	P04150	NR3C1	Q00535	CDK5	S226	E231K	231	Missense	distal	5	no	16.746	16.997	EPSD;PhosphoSitePlus	ICGC;COSMIC	8.808	Up-regulation
CMGC_CDK_CDK5_CDK5_ST	P04150	NR3C1	Q00535	CDK5	S267	S269G	269	Missense	proximal	2	no	17.611	17.537	EPSD	ICGC	8.808	Down-regulation
CMGC_CDK_CDK5_CDK5_ST	P04150	NR3C1	Q00535	CDK5	S267	S269N	269	Missense	proximal	2	no	17.611	17.565	EPSD	ICGC;COSMIC	8.808	Down-regulation
CMGC_CDK_CDK5_CDK5_ST	P04150	NR3C1	Q00535	CDK5	S269	S269G	269	Missense	central	0	yes	9.230	0.000	EPSD	ICGC	8.808	Loss
CMGC_CDK_CDK5_CDK5_ST	P04150	NR3C1	Q00535	CDK5	S269	S269N	269	Missense	central	0	yes	9.230	0.000	EPSD	ICGC;COSMIC	8.808	Loss
CMGC_CDK_CDK5_CDK5_ST	P04150	NR3C1	Q00535	CDK5	S404	T411S	411	Missense	distal	7	no	18.779	18.781	EPSD	ICGC;COSMIC	8.808	Up-regulation
CMGC_CDK_CDK5_CDK5_ST	P04150	NR3C1	Q00535	CDK5	S410	T411S	411	Missense	proximal	1	no	9.188	7.775	EPSD	ICGC;COSMIC	8.808	Loss
CMGC_CDK_CDK5_CDK5_ST	P04150	NR3C1	Q00535	CDK5	S508	Q502H	502	Missense	distal	-6	no	9.043	9.036	EPSD	ICGC;COSMIC	8.808	Down-regulation
CMGC_CDK_CDK5_CDK5_ST	P04150	NR3C1	Q00535	CDK5	S508	P515T	515	Missense	distal	7	no	9.043	9.042	EPSD	ICGC	8.808	Down-regulation
CMGC_CDK_CDK5_CDK5_ST	P04150	NR3C1	Q00535	CDK5	S508	E510D	510	Missense	proximal	2	no	9.043	9.039	EPSD	ICGC	8.808	Down-regulation
CMGC_CDK_CDK5_CDK5_ST	Q8NEB9	PIK3C3	Q00535	CDK5	S448	L450F	450	Missense	proximal	2	no	17.073	17.011	EPSD	ICGC	8.808	Down-regulation
CMGC_CDK_CDK5_CDK5_ST	Q8NEB9	PIK3C3	Q00535	CDK5	S455	L450F	450	Missense	distal	-5	no	18.397	18.287	EPSD	ICGC	8.808	Down-regulation
CMGC_CDK_CDK5_CDK5_ST	Q8NEB9	PIK3C3	Q00535	CDK5	S455	P457H	457	Missense	proximal	2	no	18.397	18.364	EPSD	ICGC;COSMIC	8.808	Down-regulation
CMGC_CDK_CDK5_CDK5_ST	Q8NEB9	PIK3C3	Q00535	CDK5	S455	P457T	457	Missense	proximal	2	no	18.397	18.404	EPSD	ICGC;COSMIC	8.808	Up-regulation
CMGC_CDK_CDK5_CDK5_ST	P56817	BACE1	Q00535	CDK5	S83	S83R	83	Missense	central	0	yes	17.349	0.000	EPSD	ICGC	8.808	Loss
CMGC_CDK_CDK5_CDK5_ST	P56817	BACE1	Q00535	CDK5	S83	Q86E	86	Missense	distal	3	no	17.349	17.185	EPSD	ICGC;COSMIC	8.808	Down-regulation
CMGC_CDK_CDK5_CDK5_ST	P56817	BACE1	Q00535	CDK5	S83	P85L	85	Missense	proximal	2	no	17.349	17.183	EPSD	ICGC;COSMIC	8.808	Down-regulation
CMGC_CDK_CDK5_CDK5_ST	P56817	BACE1	Q00535	CDK5	S83	G82C	82	Missense	proximal	-1	no	17.349	17.347	EPSD	ICGC;COSMIC	8.808	Down-regulation
CMGC_CDK_CDK5_CDK5_ST	P05067	APP	Q00535	CDK5	T381	E385Q	385	Missense	distal	4	no	16.419	16.443	EPSD	ICGC;COSMIC	8.808	Up-regulation
CMGC_CDK_CDK5_CDK5_ST	P49418	AMPH	Q00535	CDK5	T260	T260I	260	Missense	central	0	yes	17.115	0.000	EPSD	ICGC	8.808	Loss
CMGC_CDK_CDK5_CDK5_ST	P49418	AMPH	Q00535	CDK5	T260	R256C	256	Missense	distal	-4	no	17.115	16.553	EPSD	ICGC;COSMIC	8.808	Down-regulation
CMGC_CDK_CDK5_CDK5_ST	P49418	AMPH	Q00535	CDK5	T260	G253C	253	Missense	distal	-7	no	17.115	17.095	EPSD	ICGC;COSMIC	8.808	Down-regulation
CMGC_CDK_CDK5_CDK5_ST	P49418	AMPH	Q00535	CDK5	T260	R256P	256	Missense	distal	-4	no	17.115	17.231	EPSD	ICGC;COSMIC	8.808	Up-regulation
CMGC_CDK_CDK5_CDK5_ST	P49418	AMPH	Q00535	CDK5	T260	P254H	254	Missense	distal	-6	no	17.115	17.095	EPSD	ICGC;COSMIC	8.808	Down-regulation
CMGC_CDK_CDK5_CDK5_ST	P49418	AMPH	Q00535	CDK5	S262	T260I	260	Missense	proximal	-2	no	17.302	17.120	EPSD	ICGC	8.808	Down-regulation
CMGC_CDK_CDK5_CDK5_ST	P49418	AMPH	Q00535	CDK5	S262	P269H	269	Missense	distal	7	no	17.302	17.298	EPSD	ICGC;GDSC;CCLE	8.808	Down-regulation
CMGC_CDK_CDK5_CDK5_ST	P49418	AMPH	Q00535	CDK5	S262	R256C	256	Missense	distal	-6	no	17.302	17.150	EPSD	ICGC;COSMIC	8.808	Down-regulation
CMGC_CDK_CDK5_CDK5_ST	P49418	AMPH	Q00535	CDK5	S262	R256P	256	Missense	distal	-6	no	17.302	17.256	EPSD	ICGC;COSMIC	8.808	Down-regulation
CMGC_CDK_CDK5_CDK5_ST	P49418	AMPH	Q00535	CDK5	S268	P269H	269	Missense	proximal	1	no	17.965	-0.547	EPSD	ICGC;GDSC;CCLE	8.808	Loss
CMGC_CDK_CDK5_CDK5_ST	P49418	AMPH	Q00535	CDK5	S268	P271Q	271	Missense	distal	3	no	17.965	17.560	EPSD	ICGC;COSMIC	8.808	Down-regulation
CMGC_CDK_CDK5_CDK5_ST	P49418	AMPH	Q00535	CDK5	S272	P269H	269	Missense	distal	-3	no	18.353	18.330	EPSD;PhosphoSitePlus	ICGC;GDSC;CCLE	8.808	Down-regulation
CMGC_CDK_CDK5_CDK5_ST	P49418	AMPH	Q00535	CDK5	S272	P271Q	271	Missense	proximal	-1	no	18.353	18.352	EPSD;PhosphoSitePlus	ICGC;COSMIC	8.808	Down-regulation
CMGC_CDK_CDK5_CDK5_ST	P49418	AMPH	Q00535	CDK5	S276	P269H	269	Missense	distal	-7	no	18.246	18.219	EPSD;PhosphoSitePlus	ICGC;GDSC;CCLE	8.808	Down-regulation
CMGC_CDK_CDK5_CDK5_ST	P49418	AMPH	Q00535	CDK5	S276	P271Q	271	Missense	distal	-5	no	18.246	18.188	EPSD;PhosphoSitePlus	ICGC;COSMIC	8.808	Down-regulation
CMGC_CDK_CDK5_CDK5_ST	P49418	AMPH	Q00535	CDK5	S285	P288S	288	Missense	distal	3	no	17.350	17.331	PhosphoSitePlus;EPSD	ICGC;COSMIC	8.808	Down-regulation
CMGC_CDK_CDK5_CDK5_ST	P49418	AMPH	Q00535	CDK5	S285	A289E	289	Missense	distal	4	no	17.350	17.360	PhosphoSitePlus;EPSD	ICGC	8.808	Up-regulation
CMGC_CDK_CDK5_CDK5_ST	P49418	AMPH	Q00535	CDK5	S293	P288S	288	Missense	distal	-5	no	16.929	16.951	EPSD	ICGC;COSMIC	8.808	Up-regulation
CMGC_CDK_CDK5_CDK5_ST	P49418	AMPH	Q00535	CDK5	S293	A289E	289	Missense	distal	-4	no	16.929	17.203	EPSD	ICGC	8.808	Up-regulation
CMGC_CDK_CDK5_CDK5_ST	P49418	AMPH	Q00535	CDK5	S295	P288S	288	Missense	distal	-7	no	10.870	10.875	EPSD	ICGC;COSMIC	8.808	Up-regulation
CMGC_CDK_CDK5_CDK5_ST	P49418	AMPH	Q00535	CDK5	S295	P301T	301	Missense	distal	6	no	10.870	10.871	EPSD	ICGC	8.808	Up-regulation
CMGC_CDK_CDK5_CDK5_ST	P49418	AMPH	Q00535	CDK5	S295	A289E	289	Missense	distal	-6	no	10.870	10.897	EPSD	ICGC	8.808	Up-regulation
CMGC_CDK_CDK5_CDK5_ST	P49418	AMPH	Q00535	CDK5	T310	K313N	313	Missense	distal	3	no	18.925	16.992	EPSD	ICGC;COSMIC	8.808	Down-regulation
CMGC_CDK_CDK5_CDK5_ST	P49418	AMPH	Q00535	CDK5	T336	E331K	331	Missense	distal	-5	no	15.867	16.157	EPSD	ICGC;COSMIC	8.808	Up-regulation
CMGC_CDK_CDK5_CDK5_ST	P49418	AMPH	Q00535	CDK5	T336	P330T	330	Missense	distal	-6	no	15.867	15.878	EPSD	ICGC;COSMIC	8.808	Up-regulation
CMGC_CDK_CDK5_CDK5_ST	P49418	AMPH	Q00535	CDK5	T336	T335K	335	Missense	proximal	-1	no	15.867	15.870	EPSD	ICGC	8.808	Up-regulation
CMGC_CDK_CDK5_CDK5_ST	P49418	AMPH	Q00535	CDK5	T336	V342F	342	Missense	distal	6	no	15.867	15.850	EPSD	ICGC	8.808	Down-regulation
CMGC_CDK_CDK5_CDK5_ST	P49418	AMPH	Q00535	CDK5	T336	P330S	330	Missense	distal	-6	no	15.867	15.906	EPSD	ICGC	8.808	Up-regulation
CMGC_CDK_CDK5_CDK5_ST	P49418	AMPH	Q00535	CDK5	T336	P330A	330	Missense	distal	-6	no	15.867	15.792	EPSD	ICGC;COSMIC	8.808	Down-regulation
CMGC_CDK_CDK5_CDK5_ST	P49418	AMPH	Q00535	CDK5	T336	P343H	343	Missense	distal	7	no	15.867	15.863	EPSD	ICGC;COSMIC	8.808	Down-regulation
CMGC_CDK_CDK5_CDK5_ST	P49418	AMPH	Q00535	CDK5	T445	D451E	451	Missense	distal	6	no	16.941	16.942	EPSD	ICGC	8.808	Up-regulation
CMGC_CDK_CDK5_CDK5_ST	P49418	AMPH	Q00535	CDK5	T445	E439K	439	Missense	distal	-6	no	16.941	17.070	EPSD	ICGC	8.808	Up-regulation
CMGC_CDK_CDK5_CDK5_ST	P49418	AMPH	Q00535	CDK5	T445	L441M	441	Missense	distal	-4	no	16.941	16.690	EPSD	ICGC	8.808	Down-regulation
CMGC_CDK_CDK5_CDK5_ST	Q15078	CDK5R1	Q00535	CDK5	S8	R12L	12	Missense	distal	4	no	18.241	18.141	PhosphoSitePlus;EPSD	ICGC;COSMIC	8.808	Down-regulation
CMGC_CDK_CDK5_CDK5_ST	Q15078	CDK5R1	Q00535	CDK5	T138	T138M	138	Missense	central	0	yes	19.097	0.000	EPSD;PhosphoSitePlus	ICGC;COSMIC;GDSC;CCLE	8.808	Loss
CMGC_CDK_CDK5_CDK5_ST	Q15078	CDK5R1	Q00535	CDK5	T138	S135F	135	Missense	distal	-3	no	19.097	19.019	EPSD;PhosphoSitePlus	ICGC	8.808	Down-regulation
CMGC_CDK_CDK5_CDK5_ST	Q15078	CDK5R1	Q00535	CDK5	T138	R141L	141	Missense	distal	3	no	19.097	16.627	EPSD;PhosphoSitePlus	ICGC;COSMIC	8.808	Down-regulation
CMGC_CDK_CDK5_CDK5_ST	Q96QB1	DLC1	Q00535	CDK5	S306	H302N	302	Missense	distal	-4	no	19.469	19.637	EPSD	ICGC;COSMIC	8.808	Up-regulation
CMGC_CDK_CDK5_CDK5_ST	Q96QB1	DLC1	Q00535	CDK5	S378	S374R	374	Missense	distal	-4	no	18.836	18.375	EPSD	ICGC	8.808	Down-regulation
CMGC_CDK_CDK5_CDK5_ST	Q96QB1	DLC1	Q00535	CDK5	S378	P383Q	383	Missense	distal	5	no	18.836	18.787	EPSD	ICGC	8.808	Down-regulation
CMGC_CDK_CDK5_CDK5_ST	Q96QB1	DLC1	Q00535	CDK5	T382	P383Q	383	Missense	proximal	1	no	18.246	9.270	EPSD	ICGC	8.808	Down-regulation
CMGC_CDK_CDK5_CDK5_ST	Q96QB1	DLC1	Q00535	CDK5	T382	R387L	387	Missense	distal	5	no	18.246	17.998	EPSD	ICGC;COSMIC	8.808	Down-regulation
CMGC_CDK_CDK5_CDK5_ST	Q96QB1	DLC1	Q00535	CDK5	T384	P383Q	383	Missense	proximal	-1	no	10.132	10.131	EPSD	ICGC	8.808	Down-regulation
CMGC_CDK_CDK5_CDK5_ST	Q96QB1	DLC1	Q00535	CDK5	T384	R387L	387	Missense	distal	3	no	10.132	7.662	EPSD	ICGC;COSMIC	8.808	Loss
CMGC_CDK_CDK5_CDK5_ST	Q96QB1	DLC1	Q00535	CDK5	S577	S577R	577	Missense	central	0	yes	18.155	0.000	EPSD	ICGC;COSMIC	8.808	Loss
CMGC_CDK_CDK5_CDK5_ST	Q96QB1	DLC1	Q00535	CDK5	S859	S859Y	859	Missense	central	0	yes	17.929	0.000	EPSD;PhosphoSitePlus	ICGC;COSMIC	8.808	Loss
CMGC_CDK_CDK5_CDK5_ST	Q96QB1	DLC1	Q00535	CDK5	S874	L876M	876	Missense	proximal	2	no	9.351	9.326	EPSD	ICGC;COSMIC	8.808	Down-regulation
CMGC_CDK_CDK5_CDK5_ST	Q96QB1	DLC1	Q00535	CDK5	S874	D880Y	880	Missense	distal	6	no	9.351	9.348	EPSD	ICGC;COSMIC	8.808	Down-regulation
CMGC_CDK_CDK5_CDK5_ST	Q96QB1	DLC1	Q00535	CDK5	S941	P947T	947	Missense	distal	6	no	17.171	17.172	EPSD	ICGC;COSMIC	8.808	Up-regulation
CMGC_CDK_CDK5_CDK5_ST	Q96QB1	DLC1	Q00535	CDK5	S946	P947T	947	Missense	proximal	1	no	18.082	7.594	EPSD;PhosphoSitePlus	ICGC;COSMIC	8.808	Loss
CMGC_CDK_CDK5_CDK5_ST	Q96QB1	DLC1	Q00535	CDK5	S995	R994I	994	Missense	proximal	-1	no	9.504	9.501	EPSD	ICGC	8.808	Down-regulation
CMGC_CDK_CDK5_CDK5_ST	Q96QB1	DLC1	Q00535	CDK5	S1516	R1512Q	1512	Missense	distal	-4	no	9.023	9.013	EPSD	ICGC;COSMIC;GDSC;CCLE	8.808	Down-regulation
CMGC_CDK_CDK5_CDK5_ST	P30086	PEBP1	Q00535	CDK5	T42	N48D	48	Missense	distal	6	no	16.427	16.421	PhosphoSitePlus	ICGC;COSMIC	8.808	Down-regulation
CMGC_CDK_CDK5_CDK5_ST	P30086	PEBP1	Q00535	CDK5	T42	L37M	37	Missense	distal	-5	no	16.427	16.364	PhosphoSitePlus	ICGC;COSMIC	8.808	Down-regulation
CMGC_CDK_CDK5_CDK5_ST	P30086	PEBP1	Q00535	CDK5	T44	N48D	48	Missense	distal	4	no	10.246	10.216	EPSD	ICGC;COSMIC	8.808	Down-regulation
CMGC_CDK_CDK5_CDK5_ST	P30086	PEBP1	Q00535	CDK5	T44	L37M	37	Missense	distal	-7	no	10.246	10.230	EPSD	ICGC;COSMIC	8.808	Down-regulation
CMGC_CDK_CDK5_CDK5_ST	Q3V6T2	CCDC88A	Q00535	CDK5	S16	S16R	16	Missense	central	0	yes	18.744	0.000	EPSD	ICGC;COSMIC	8.808	Loss
CMGC_CDK_CDK5_CDK5_ST	Q3V6T2	CCDC88A	Q00535	CDK5	S16	Q12K	12	Missense	distal	-4	no	18.744	19.091	EPSD	ICGC;COSMIC	8.808	Up-regulation
CMGC_CDK_CDK5_CDK5_ST	Q3V6T2	CCDC88A	Q00535	CDK5	S245	L249P	249	Missense	distal	4	no	9.460	9.541	EPSD	ICGC	8.808	Up-regulation
CMGC_CDK_CDK5_CDK5_ST	Q3V6T2	CCDC88A	Q00535	CDK5	S245	L249M	249	Missense	distal	4	no	9.460	9.448	EPSD	ICGC;COSMIC	8.808	Down-regulation
CMGC_CDK_CDK5_CDK5_ST	Q3V6T2	CCDC88A	Q00535	CDK5	S245	S250W	250	Missense	distal	5	no	9.460	9.346	EPSD	ICGC;COSMIC	8.808	Down-regulation
CMGC_CDK_CDK5_CDK5_ST	Q3V6T2	CCDC88A	Q00535	CDK5	S775	L782I	782	Missense	distal	7	no	10.461	10.467	EPSD	ICGC	8.808	Up-regulation
CMGC_CDK_CDK5_CDK5_ST	Q3V6T2	CCDC88A	Q00535	CDK5	S1034	T1037S	1037	Missense	distal	3	no	9.591	9.035	EPSD	ICGC	8.808	Down-regulation
CMGC_CDK_CDK5_CDK5_ST	Q3V6T2	CCDC88A	Q00535	CDK5	S1387	P1388S	1388	Missense	proximal	1	no	17.968	6.067	EPSD	ICGC;COSMIC	8.808	Loss
CMGC_CDK_CDK5_CDK5_ST	Q3V6T2	CCDC88A	Q00535	CDK5	S1790	S1790Y	1790	Missense	central	0	yes	8.818	0.000	EPSD	ICGC;COSMIC	8.808	Loss
CMGC_CDK_CDK5_CDK5_ST	P14416	DRD2	Q00535	CDK5	S19	F22L	22	Missense	distal	3	no	9.063	9.189	EPSD	ICGC;COSMIC	8.808	Up-regulation
CMGC_CDK_CDK5_CDK5_ST	P14416	DRD2	Q00535	CDK5	S296	S301N	301	Missense	distal	5	no	17.780	17.716	EPSD	ICGC;COSMIC	8.808	Down-regulation
CMGC_CDK_CDK5_CDK5_ST	P14416	DRD2	Q00535	CDK5	S296	P297L	297	Missense	proximal	1	no	17.780	5.830	EPSD	ICGC;COSMIC	8.808	Loss
CMGC_CDK_CDK5_CDK5_ST	P14416	DRD2	Q00535	CDK5	S296	P299Q	299	Missense	distal	3	no	17.780	17.375	EPSD	ICGC	8.808	Down-regulation
CMGC_CDK_CDK5_CDK5_ST	P14416	DRD2	Q00535	CDK5	S296	P300T	300	Missense	distal	4	no	17.780	17.779	EPSD	ICGC	8.808	Down-regulation
CMGC_CDK_CDK5_CDK5_ST	P14416	DRD2	Q00535	CDK5	S296	P290L	290	Missense	distal	-6	no	17.780	17.697	EPSD	ICGC;COSMIC	8.808	Down-regulation
CMGC_CDK_CDK5_CDK5_ST	P14416	DRD2	Q00535	CDK5	S321	K327N	327	Missense	distal	6	no	20.081	20.067	PhosphoSitePlus	ICGC;COSMIC	8.808	Down-regulation
CMGC_CDK_CDK5_CDK5_ST	P14416	DRD2	Q00535	CDK5	S321	D320N	320	Missense	proximal	-1	no	20.081	20.083	PhosphoSitePlus	ICGC;COSMIC	8.808	Up-regulation
CMGC_CDK_CDK5_CDK5_ST	P14416	DRD2	Q00535	CDK5	S321	K324N	324	Missense	distal	3	no	20.081	18.148	PhosphoSitePlus	ICGC;COSMIC	8.808	Down-regulation
CMGC_CDK_CDK5_CDK5_ST	Q13136	PPFIA1	Q00535	CDK5	S26	G20E	20	Missense	distal	-6	no	18.306	18.313	EPSD	ICGC;COSMIC	8.808	Up-regulation
CMGC_CDK_CDK5_CDK5_ST	Q13136	PPFIA1	Q00535	CDK5	S26	Q29H	29	Missense	distal	3	no	18.306	19.090	EPSD	ICGC;COSMIC	8.808	Up-regulation
CMGC_CDK_CDK5_CDK5_ST	Q13136	PPFIA1	Q00535	CDK5	S26	D33Y	33	Missense	distal	7	no	18.306	18.302	EPSD	ICGC	8.808	Down-regulation
CMGC_CDK_CDK5_CDK5_ST	Q13136	PPFIA1	Q00535	CDK5	S28	Q29H	29	Missense	proximal	1	no	9.567	0.030	EPSD	ICGC;COSMIC	8.808	Loss
CMGC_CDK_CDK5_CDK5_ST	Q13136	PPFIA1	Q00535	CDK5	S28	D33Y	33	Missense	distal	5	no	9.567	9.522	EPSD	ICGC	8.808	Down-regulation
CMGC_CDK_CDK5_CDK5_ST	Q13136	PPFIA1	Q00535	CDK5	S150	Q147K	147	Missense	distal	-3	no	18.030	18.076	EPSD	ICGC;COSMIC	8.808	Up-regulation
CMGC_CDK_CDK5_CDK5_ST	Q13136	PPFIA1	Q00535	CDK5	T230	E228A	228	Missense	proximal	-2	no	17.080	17.144	EPSD	ICGC;COSMIC	8.808	Up-regulation
CMGC_CDK_CDK5_CDK5_ST	Q13136	PPFIA1	Q00535	CDK5	S618	D624N	624	Missense	distal	6	no	18.198	18.204	EPSD	ICGC	8.808	Up-regulation
CMGC_CDK_CDK5_CDK5_ST	Q13136	PPFIA1	Q00535	CDK5	S618	S618L	618	Missense	central	0	yes	18.198	0.000	EPSD	ICGC;COSMIC;GDSC;CCLE	8.808	Loss
CMGC_CDK_CDK5_CDK5_ST	Q13136	PPFIA1	Q00535	CDK5	S693	A690S	690	Missense	distal	-3	no	18.047	18.094	EPSD	ICGC;COSMIC	8.808	Up-regulation
CMGC_CDK_CDK5_CDK5_ST	Q13136	PPFIA1	Q00535	CDK5	S693	A686S	686	Missense	distal	-7	no	18.047	18.101	EPSD	ICGC	8.808	Up-regulation
CMGC_CDK_CDK5_CDK5_ST	Q13136	PPFIA1	Q00535	CDK5	S693	R699L	699	Missense	distal	6	no	18.047	18.025	EPSD	ICGC;COSMIC	8.808	Down-regulation
CMGC_CDK_CDK5_CDK5_ST	Q13136	PPFIA1	Q00535	CDK5	S693	G698K	698	Missense	distal	5	no	18.047	18.289	EPSD	ICGC	8.808	Up-regulation
CMGC_CDK_CDK5_CDK5_ST	Q13136	PPFIA1	Q00535	CDK5	S693	G698W	698	Missense	distal	5	no	18.047	18.037	EPSD	ICGC;COSMIC	8.808	Down-regulation
CMGC_CDK_CDK5_CDK5_ST	Q13136	PPFIA1	Q00535	CDK5	S700	G698K	698	Missense	proximal	-2	no	8.750	9.186	EPSD	ICGC	8.808	Gain
CMGC_CDK_CDK5_CDK5_ST	Q13136	PPFIA1	Q00535	CDK5	T701	S708I	708	Missense	distal	7	no	19.303	19.297	PhosphoSitePlus	ICGC;COSMIC	8.808	Down-regulation
CMGC_CDK_CDK5_CDK5_ST	Q13136	PPFIA1	Q00535	CDK5	T701	R699L	699	Missense	proximal	-2	no	19.303	18.943	PhosphoSitePlus	ICGC;COSMIC	8.808	Down-regulation
CMGC_CDK_CDK5_CDK5_ST	Q13136	PPFIA1	Q00535	CDK5	T701	G698K	698	Missense	distal	-3	no	19.303	19.378	PhosphoSitePlus	ICGC	8.808	Up-regulation
CMGC_CDK_CDK5_CDK5_ST	Q13136	PPFIA1	Q00535	CDK5	T701	G698W	698	Missense	distal	-3	no	19.303	19.305	PhosphoSitePlus	ICGC;COSMIC	8.808	Up-regulation
CMGC_CDK_CDK5_CDK5_ST	Q13136	PPFIA1	Q00535	CDK5	S708	S708I	708	Missense	central	0	yes	19.095	0.000	EPSD	ICGC;COSMIC	8.808	Loss
CMGC_CDK_CDK5_CDK5_ST	Q13136	PPFIA1	Q00535	CDK5	S708	P709L	709	Missense	proximal	1	no	19.095	7.145	EPSD	ICGC	8.808	Loss
CMGC_CDK_CDK5_CDK5_ST	Q13136	PPFIA1	Q00535	CDK5	S741	P742T	742	Missense	proximal	1	no	18.294	7.807	EPSD	ICGC;COSMIC	8.808	Loss
CMGC_CDK_CDK5_CDK5_ST	Q13136	PPFIA1	Q00535	CDK5	S741	P742Q	742	Missense	proximal	1	no	18.294	9.318	EPSD	ICGC;COSMIC	8.808	Down-regulation
CMGC_CDK_CDK5_CDK5_ST	Q13136	PPFIA1	Q00535	CDK5	S745	P742T	742	Missense	distal	-3	no	18.291	18.284	EPSD	ICGC;COSMIC	8.808	Down-regulation
CMGC_CDK_CDK5_CDK5_ST	Q13136	PPFIA1	Q00535	CDK5	S745	P742Q	742	Missense	distal	-3	no	18.291	18.274	EPSD	ICGC;COSMIC	8.808	Down-regulation
CMGC_CDK_CDK5_CDK5_ST	Q13136	PPFIA1	Q00535	CDK5	S745	R750L	750	Missense	distal	5	no	18.291	18.043	EPSD	ICGC;COSMIC	8.808	Down-regulation
CMGC_CDK_CDK5_CDK5_ST	Q13136	PPFIA1	Q00535	CDK5	S745	R750Q	750	Missense	distal	5	no	18.291	18.166	EPSD	ICGC;COSMIC	8.808	Down-regulation
CMGC_CDK_CDK5_CDK5_ST	Q13136	PPFIA1	Q00535	CDK5	S782	P780S	780	Missense	proximal	-2	no	8.874	8.775	EPSD	ICGC;COSMIC	8.808	Loss
CMGC_CDK_CDK5_CDK5_ST	Q13136	PPFIA1	Q00535	CDK5	S787	L794F	794	Missense	distal	7	no	9.029	9.024	EPSD	ICGC;COSMIC	8.808	Down-regulation
CMGC_CDK_CDK5_CDK5_ST	Q13136	PPFIA1	Q00535	CDK5	S787	P780S	780	Missense	distal	-7	no	9.029	9.034	EPSD	ICGC;COSMIC	8.808	Up-regulation
CMGC_CDK_CDK5_CDK5_ST	Q13136	PPFIA1	Q00535	CDK5	S787	D792H	792	Missense	distal	5	no	9.029	9.122	EPSD	ICGC;COSMIC	8.808	Up-regulation
CMGC_CDK_CDK5_CDK5_ST	Q13136	PPFIA1	Q00535	CDK5	S790	L794F	794	Missense	distal	4	no	9.059	9.030	EPSD	ICGC;COSMIC	8.808	Down-regulation
CMGC_CDK_CDK5_CDK5_ST	Q13136	PPFIA1	Q00535	CDK5	S790	D792H	792	Missense	proximal	2	no	9.059	9.150	EPSD	ICGC;COSMIC	8.808	Up-regulation
CMGC_CDK_CDK5_CDK5_ST	Q13136	PPFIA1	Q00535	CDK5	S946	E940K	940	Missense	distal	-6	no	17.076	17.206	EPSD	ICGC	8.808	Up-regulation
CMGC_CDK_CDK5_CDK5_ST	Q13136	PPFIA1	Q00535	CDK5	S1139	W1140R	1140	Missense	proximal	1	no	0.295	10.154	EPSD	ICGC;COSMIC	8.808	Gain
CMGC_CDK_CDK5_CDK5_ST	Q13136	PPFIA1	Q00535	CDK5	S1172	M1175V	1175	Missense	distal	3	no	17.444	18.413	EPSD	ICGC	8.808	Up-regulation
CMGC_CDK_CDK5_CDK5_ST	Q13136	PPFIA1	Q00535	CDK5	S1172	M1175L	1175	Missense	distal	3	no	17.444	17.334	EPSD	ICGC	8.808	Down-regulation
CMGC_CDK_CDK5_CDK5_ST	Q13136	PPFIA1	Q00535	CDK5	S1172	S1172F	1172	Missense	central	0	yes	17.444	0.000	EPSD	ICGC	8.808	Loss
CMGC_CDK_CDK5_CDK5_ST	Q8IWU2	LMTK2	Q00535	CDK5	T90	E86D	86	Missense	distal	-4	no	16.399	16.351	EPSD	ICGC;COSMIC;CCLE	8.808	Down-regulation
CMGC_CDK_CDK5_CDK5_ST	Q8IWU2	LMTK2	Q00535	CDK5	S439	A443S	443	Missense	distal	4	no	8.810	8.872	EPSD	ICGC;COSMIC	8.808	Up-regulation
CMGC_CDK_CDK5_CDK5_ST	Q8IWU2	LMTK2	Q00535	CDK5	S439	N440H	440	Missense	proximal	1	no	8.810	-0.464	EPSD	ICGC	8.808	Loss
CMGC_CDK_CDK5_CDK5_ST	Q8IWU2	LMTK2	Q00535	CDK5	S630	N634D	634	Missense	distal	4	no	18.284	18.254	EPSD	ICGC;COSMIC	8.808	Down-regulation
CMGC_CDK_CDK5_CDK5_ST	Q8IWU2	LMTK2	Q00535	CDK5	S630	P631T	631	Missense	proximal	1	no	18.284	7.796	EPSD	ICGC;COSMIC	8.808	Loss
CMGC_CDK_CDK5_CDK5_ST	Q8IWU2	LMTK2	Q00535	CDK5	S810	P811S	811	Missense	proximal	1	no	18.413	6.512	EPSD	ICGC	8.808	Loss
CMGC_CDK_CDK5_CDK5_ST	Q8IWU2	LMTK2	Q00535	CDK5	S810	L807F	807	Missense	distal	-3	no	18.413	18.391	EPSD	ICGC	8.808	Down-regulation
CMGC_CDK_CDK5_CDK5_ST	Q8IWU2	LMTK2	Q00535	CDK5	S886	P887H	887	Missense	proximal	1	no	17.602	-0.910	EPSD	ICGC;COSMIC	8.808	Loss
CMGC_CDK_CDK5_CDK5_ST	Q8IWU2	LMTK2	Q00535	CDK5	T996	A989T	989	Missense	distal	-7	no	16.692	16.731	EPSD	ICGC;COSMIC	8.808	Up-regulation
CMGC_CDK_CDK5_CDK5_ST	Q8IWU2	LMTK2	Q00535	CDK5	T1088	G1081V	1081	Missense	distal	-7	no	17.139	17.173	EPSD	ICGC	8.808	Up-regulation
CMGC_CDK_CDK5_CDK5_ST	Q8IWU2	LMTK2	Q00535	CDK5	S1124	E1119D	1119	Missense	distal	-5	no	17.619	17.628	EPSD	ICGC	8.808	Up-regulation
CMGC_CDK_CDK5_CDK5_ST	Q8IWU2	LMTK2	Q00535	CDK5	S1124	S1117F	1117	Missense	distal	-7	no	17.619	17.535	EPSD	ICGC;COSMIC	8.808	Down-regulation
CMGC_CDK_CDK5_CDK5_ST	Q8IWU2	LMTK2	Q00535	CDK5	S1323	P1319S	1319	Missense	distal	-4	no	8.852	9.198	EPSD	ICGC	8.808	Up-regulation
CMGC_CDK_CDK5_CDK5_ST	Q8IWU2	LMTK2	Q00535	CDK5	S1397	G1390V	1390	Missense	distal	-7	no	17.537	17.571	EPSD	ICGC	8.808	Up-regulation
CMGC_CDK_CDK5_CDK5_ST	Q8IWU2	LMTK2	Q00535	CDK5	S1469	H1464L	1464	Missense	distal	-5	no	9.433	9.306	EPSD	ICGC;COSMIC	8.808	Down-regulation
CMGC_CDK_CDK5_CDK5_ST	Q8IWU2	LMTK2	Q00535	CDK5	S1469	S1474C	1474	Missense	distal	5	no	9.433	9.240	EPSD	ICGC;COSMIC	8.808	Down-regulation
CMGC_CDK_CDK5_CDK5_ST	Q8IWU2	LMTK2	Q00535	CDK5	S1469	R1470Q	1470	Missense	proximal	1	no	9.433	9.405	EPSD	ICGC;COSMIC;GDSC	8.808	Down-regulation
CMGC_CDK_CDK5_CDK5_ST	Q8IWU2	LMTK2	Q00535	CDK5	S1469	A1466V	1466	Missense	distal	-3	no	9.433	9.472	EPSD	ICGC;COSMIC	8.808	Up-regulation
CMGC_CDK_CDK5_CDK5_ST	P47989	XDH	Q00535	CDK5	S192	H187N	187	Missense	distal	-5	no	17.464	17.465	EPSD	ICGC	8.808	Up-regulation
CMGC_CDK_CDK5_CDK5_ST	P47989	XDH	Q00535	CDK5	S194	H187N	187	Missense	distal	-7	no	9.323	9.328	EPSD	ICGC	8.808	Up-regulation
CMGC_CDK_CDK5_CDK5_ST	P47989	XDH	Q00535	CDK5	S194	E200G	200	Missense	distal	6	no	9.323	9.322	EPSD	ICGC	8.808	Down-regulation
CMGC_CDK_CDK5_CDK5_ST	P47989	XDH	Q00535	CDK5	T202	E200G	200	Missense	proximal	-2	no	16.353	16.330	EPSD	ICGC	8.808	Down-regulation
CMGC_CDK_CDK5_CDK5_ST	P47989	XDH	Q00535	CDK5	T202	P203L	203	Missense	proximal	1	no	16.353	4.403	EPSD	ICGC	8.808	Loss
CMGC_CDK_CDK5_CDK5_ST	P47989	XDH	Q00535	CDK5	T222	T222N	222	Missense	central	0	yes	18.965	0.000	PhosphoSitePlus	ICGC	8.808	Loss
CMGC_CDK_CDK5_CDK5_ST	P47989	XDH	Q00535	CDK5	T222	R228G	228	Missense	distal	6	no	18.965	18.948	PhosphoSitePlus	ICGC;COSMIC	8.808	Down-regulation
CMGC_CDK_CDK5_CDK5_ST	P47989	XDH	Q00535	CDK5	S356	D360N	360	Missense	distal	4	no	17.577	17.608	EPSD	ICGC	8.808	Up-regulation
CMGC_CDK_CDK5_CDK5_ST	P47989	XDH	Q00535	CDK5	S399	I403T	403	Missense	distal	4	no	17.108	17.149	EPSD	ICGC;COSMIC	8.808	Up-regulation
CMGC_CDK_CDK5_CDK5_ST	P47989	XDH	Q00535	CDK5	S399	P400L	400	Missense	proximal	1	no	17.108	5.158	EPSD	ICGC	8.808	Loss
CMGC_CDK_CDK5_CDK5_ST	P47989	XDH	Q00535	CDK5	T804	G801R	801	Missense	distal	-3	no	8.916	8.972	EPSD	ICGC;COSMIC	8.808	Up-regulation
CMGC_CDK_CDK5_CDK5_ST	P47989	XDH	Q00535	CDK5	S1299	P1303L	1303	Missense	distal	4	no	17.607	17.525	EPSD	ICGC;COSMIC	8.808	Down-regulation
CMGC_CDK_CDK5_CDK5_ST	P47989	XDH	Q00535	CDK5	S1299	P1300T	1300	Missense	proximal	1	no	17.607	7.120	EPSD	ICGC	8.808	Loss
CMGC_CDK_CDK5_CDK5_ST	P47989	XDH	Q00535	CDK5	S1299	F1295C	1295	Missense	distal	-4	no	17.607	17.744	EPSD	ICGC	8.808	Up-regulation
CMGC_CDK_CDK5_CDK5_ST	P47989	XDH	Q00535	CDK5	S1299	F1295L	1295	Missense	distal	-4	no	17.607	17.948	EPSD	ICGC;COSMIC	8.808	Up-regulation
CMGC_CDK_CDK5_CDK5_ST	Q12778	FOXO1	Q00535	CDK5	S287	S293Y	293	Missense	distal	6	no	17.004	16.989	EPSD	ICGC;COSMIC	8.808	Down-regulation
CMGC_CDK_CDK5_CDK5_ST	Q12778	FOXO1	Q00535	CDK5	S287	A284D	284	Missense	distal	-3	no	17.004	17.010	EPSD	ICGC	8.808	Up-regulation
CMGC_CDK_CDK5_CDK5_ST	Q12778	FOXO1	Q00535	CDK5	S287	Q281K	281	Missense	distal	-6	no	17.004	17.097	EPSD	ICGC;COSMIC	8.808	Up-regulation
CMGC_CDK_CDK5_CDK5_ST	Q12778	FOXO1	Q00535	CDK5	S298	S293Y	293	Missense	distal	-5	no	18.003	17.753	EPSD	ICGC;COSMIC	8.808	Down-regulation
CMGC_CDK_CDK5_CDK5_ST	Q12778	FOXO1	Q00535	CDK5	S329	E334K	334	Missense	distal	5	no	17.354	17.605	EPSD	ICGC;COSMIC;CCLE	8.808	Up-regulation
CMGC_CDK_CDK5_CDK5_ST	Q12778	FOXO1	Q00535	CDK5	S329	G326V	326	Missense	distal	-3	no	17.354	17.386	EPSD	ICGC;COSMIC	8.808	Up-regulation
CMGC_CDK_CDK5_CDK5_ST	Q12778	FOXO1	Q00535	CDK5	S351	M346T	346	Missense	distal	-5	no	8.602	8.860	EPSD	ICGC;COSMIC	8.808	Gain
CMGC_CDK_CDK5_CDK5_ST	Q12778	FOXO1	Q00535	CDK5	S383	P384T	384	Missense	proximal	1	no	17.450	6.963	EPSD	ICGC	8.808	Loss
CMGC_CDK_CDK5_CDK5_ST	Q12778	FOXO1	Q00535	CDK5	S394	Q392K	392	Missense	proximal	-2	no	18.794	18.957	EPSD	ICGC	8.808	Up-regulation
CMGC_CDK_CDK5_CDK5_ST	Q12778	FOXO1	Q00535	CDK5	T402	P403S	403	Missense	proximal	1	no	16.071	4.170	EPSD	ICGC	8.808	Loss
CMGC_CDK_CDK5_CDK5_ST	Q12778	FOXO1	Q00535	CDK5	T402	P409T	409	Missense	distal	7	no	16.071	16.069	EPSD	ICGC	8.808	Down-regulation
CMGC_CDK_CDK5_CDK5_ST	Q12778	FOXO1	Q00535	CDK5	T402	P409Q	409	Missense	distal	7	no	16.071	16.067	EPSD	ICGC	8.808	Down-regulation
CMGC_CDK_CDK5_CDK5_ST	Q12778	FOXO1	Q00535	CDK5	S416	P410Q	410	Missense	distal	-6	no	17.205	17.193	EPSD	ICGC	8.808	Down-regulation
CMGC_CDK_CDK5_CDK5_ST	Q12778	FOXO1	Q00535	CDK5	S416	P409T	409	Missense	distal	-7	no	17.205	17.195	EPSD	ICGC	8.808	Down-regulation
CMGC_CDK_CDK5_CDK5_ST	Q12778	FOXO1	Q00535	CDK5	S416	P409Q	409	Missense	distal	-7	no	17.205	17.189	EPSD	ICGC	8.808	Down-regulation
CMGC_CDK_CDK5_CDK5_ST	Q12778	FOXO1	Q00535	CDK5	S470	D475E	475	Missense	distal	5	no	17.499	17.519	EPSD	ICGC	8.808	Up-regulation
CMGC_CDK_CDK5_CDK5_ST	Q12778	FOXO1	Q00535	CDK5	S470	L465F	465	Missense	distal	-5	no	17.499	17.389	EPSD	ICGC;COSMIC	8.808	Down-regulation
CMGC_CDK_CDK5_CDK5_ST	Q12778	FOXO1	Q00535	CDK5	T478	D475E	475	Missense	distal	-3	no	17.043	17.045	EPSD	ICGC	8.808	Up-regulation
CMGC_CDK_CDK5_CDK5_ST	Q12778	FOXO1	Q00535	CDK5	T478	G483V	483	Missense	distal	5	no	17.043	17.109	EPSD	ICGC;COSMIC	8.808	Up-regulation
CMGC_CDK_CDK5_CDK5_ST	Q12778	FOXO1	Q00535	CDK5	T648	S651R	651	Missense	distal	3	no	8.674	10.092	EPSD	ICGC	8.808	Gain
CMGC_CDK_CDK5_CDK5_ST	Q13794	PMAIP1	Q00535	CDK5	S13	R16L	16	Missense	distal	3	no	21.053	18.583	PhosphoSitePlus	ICGC;COSMIC	8.808	Down-regulation
CMGC_CDK_CDK5_CDK5_ST	Q13794	PMAIP1	Q00535	CDK5	S13	P14L	14	Missense	proximal	1	no	21.053	9.103	PhosphoSitePlus	ICGC	8.808	Down-regulation
CMGC_CDK_CDK5_CDK5_ST	Q13794	PMAIP1	Q00535	CDK5	S13	R7L	7	Missense	distal	-6	no	21.053	20.924	PhosphoSitePlus	ICGC;COSMIC	8.808	Down-regulation
CMGC_CDK_CDK5_CDK5_ST	Q16643	DBN1	Q00535	CDK5	S73	P78T	78	Missense	distal	5	no	9.549	9.561	EPSD	ICGC;COSMIC	8.808	Up-regulation
CMGC_CDK_CDK5_CDK5_ST	Q16643	DBN1	Q00535	CDK5	S142	L140H	140	Missense	proximal	-2	no	16.195	16.294	PhosphoSitePlus;EPSD	ICGC;COSMIC	8.808	Up-regulation
CMGC_CDK_CDK5_CDK5_ST	Q16643	DBN1	Q00535	CDK5	S142	R139Q	139	Missense	distal	-3	no	16.195	16.169	PhosphoSitePlus;EPSD	ICGC	8.808	Down-regulation
CMGC_CDK_CDK5_CDK5_ST	Q16643	DBN1	Q00535	CDK5	T267	H268N	268	Missense	proximal	1	no	-0.420	8.854	EPSD	ICGC;COSMIC	8.808	Gain
CMGC_CDK_CDK5_CDK5_ST	Q16643	DBN1	Q00535	CDK5	S312	S312L	312	Missense	central	0	yes	16.665	0.000	EPSD	ICGC;COSMIC	8.808	Loss
CMGC_CDK_CDK5_CDK5_ST	Q16643	DBN1	Q00535	CDK5	S312	A305V	305	Missense	distal	-7	no	16.665	16.701	EPSD	ICGC;COSMIC	8.808	Up-regulation
CMGC_CDK_CDK5_CDK5_ST	Q16643	DBN1	Q00535	CDK5	S416	P411S	411	Missense	distal	-5	no	17.888	17.910	EPSD	ICGC;COSMIC	8.808	Up-regulation
CMGC_CDK_CDK5_CDK5_ST	Q16643	DBN1	Q00535	CDK5	T497	A495T	495	Missense	proximal	-2	no	17.058	17.296	EPSD	ICGC;COSMIC	8.808	Up-regulation
CMGC_CDK_CDK5_CDK5_ST	O43526	KCNQ2	Q00535	CDK5	S446	A451T	451	Missense	distal	5	no	18.229	18.363	PhosphoSitePlus	ICGC;COSMIC	8.808	Up-regulation
CMGC_CDK_CDK5_CDK5_ST	O43526	KCNQ2	Q00535	CDK5	S457	A451T	451	Missense	distal	-6	no	17.610	17.696	EPSD	ICGC;COSMIC	8.808	Up-regulation
CMGC_CDK_CDK5_CDK5_ST	Q9UM11	FZR1	Q00535	CDK5	T30	L31P	31	Missense	proximal	1	no	5.667	17.616	EPSD	ICGC	8.808	Gain
CMGC_CDK_CDK5_CDK5_ST	Q9UM11	FZR1	Q00535	CDK5	T32	L31P	31	Missense	proximal	-1	no	17.556	17.561	EPSD	ICGC	8.808	Up-regulation
CMGC_CDK_CDK5_CDK5_ST	Q9UM11	FZR1	Q00535	CDK5	T32	P37T	37	Missense	distal	5	no	17.556	17.568	EPSD	ICGC;COSMIC	8.808	Up-regulation
CMGC_CDK_CDK5_CDK5_ST	Q9UM11	FZR1	Q00535	CDK5	T32	P33H	33	Missense	proximal	1	no	17.556	-0.956	EPSD	ICGC;COSMIC	8.808	Loss
CMGC_CDK_CDK5_CDK5_ST	Q9UM11	FZR1	Q00535	CDK5	S36	L31P	31	Missense	distal	-5	no	17.598	17.795	EPSD	ICGC	8.808	Up-regulation
CMGC_CDK_CDK5_CDK5_ST	Q9UM11	FZR1	Q00535	CDK5	S36	P37T	37	Missense	proximal	1	no	17.598	7.110	EPSD	ICGC;COSMIC	8.808	Loss
CMGC_CDK_CDK5_CDK5_ST	Q9UM11	FZR1	Q00535	CDK5	S36	P33H	33	Missense	distal	-3	no	17.598	17.575	EPSD	ICGC;COSMIC	8.808	Down-regulation
CMGC_CDK_CDK5_CDK5_ST	Q9UM11	FZR1	Q00535	CDK5	S40	R47C	47	Missense	distal	7	no	19.875	19.858	PhosphoSitePlus;EPSD	ICGC;COSMIC	8.808	Down-regulation
CMGC_CDK_CDK5_CDK5_ST	Q9UM11	FZR1	Q00535	CDK5	S40	P37T	37	Missense	distal	-3	no	19.875	19.867	PhosphoSitePlus;EPSD	ICGC;COSMIC	8.808	Down-regulation
CMGC_CDK_CDK5_CDK5_ST	Q9UM11	FZR1	Q00535	CDK5	S40	P33H	33	Missense	distal	-7	no	19.875	19.848	PhosphoSitePlus;EPSD	ICGC;COSMIC	8.808	Down-regulation
CMGC_CDK_CDK5_CDK5_ST	Q9UM11	FZR1	Q00535	CDK5	T121	L117V	117	Missense	distal	-4	no	19.277	19.614	EPSD;PhosphoSitePlus	ICGC;COSMIC	8.808	Up-regulation
CMGC_CDK_CDK5_CDK5_ST	Q9UM11	FZR1	Q00535	CDK5	T121	K125E	125	Missense	distal	4	no	19.277	19.160	EPSD;PhosphoSitePlus	ICGC;COSMIC	8.808	Down-regulation
CMGC_CDK_CDK5_CDK5_ST	Q9UM11	FZR1	Q00535	CDK5	S138	R136L	136	Missense	proximal	-2	no	16.712	16.351	EPSD	ICGC;COSMIC	8.808	Down-regulation
CMGC_CDK_CDK5_CDK5_ST	Q9UM11	FZR1	Q00535	CDK5	S138	K135T	135	Missense	distal	-3	no	16.712	16.675	EPSD	ICGC;COSMIC	8.808	Down-regulation
CMGC_CDK_CDK5_CDK5_ST	Q9UM11	FZR1	Q00535	CDK5	S163	P164L	164	Missense	proximal	1	no	19.932	7.983	EPSD;PhosphoSitePlus	ICGC	8.808	Loss
CMGC_CDK_CDK5_CDK5_ST	Q9UM11	FZR1	Q00535	CDK5	S346	S343P	343	Missense	distal	-3	no	17.764	17.770	EPSD	ICGC;COSMIC	8.808	Up-regulation
CMGC_CDK_CDK5_CDK5_ST	P12931	SRC	Q00535	CDK5	S6	K7N	7	Missense	proximal	1	no	1.896	10.836	EPSD	ICGC	8.808	Gain
CMGC_CDK_CDK5_CDK5_ST	P12931	SRC	Q00535	CDK5	S12	K7N	7	Missense	distal	-5	no	12.092	11.885	EPSD	ICGC	8.808	Down-regulation
CMGC_CDK_CDK5_CDK5_ST	P12931	SRC	Q00535	CDK5	S12	R14L	14	Missense	proximal	2	no	12.092	11.845	EPSD	ICGC;COSMIC	8.808	Down-regulation
CMGC_CDK_CDK5_CDK5_ST	P12931	SRC	Q00535	CDK5	S12	Q13K	13	Missense	proximal	1	no	12.092	2.890	EPSD	ICGC;COSMIC	8.808	Loss
CMGC_CDK_CDK5_CDK5_ST	P12931	SRC	Q00535	CDK5	T37	S43L	43	Missense	distal	6	no	18.064	18.049	EPSD	ICGC;COSMIC	8.808	Down-regulation
CMGC_CDK_CDK5_CDK5_ST	P12931	SRC	Q00535	CDK5	T37	F32S	32	Missense	distal	-5	no	18.064	18.394	EPSD	ICGC;CCLE	8.808	Up-regulation
CMGC_CDK_CDK5_CDK5_ST	P12931	SRC	Q00535	CDK5	S75	V73I	73	Missense	proximal	-2	no	19.464	19.323	PhosphoSitePlus	ICGC;COSMIC	8.808	Down-regulation
CMGC_CDK_CDK5_CDK5_ST	P12931	SRC	Q00535	CDK5	T218	S219P	219	Missense	proximal	1	no	5.377	17.278	EPSD	ICGC	8.808	Gain
CMGC_CDK_CDK5_CDK5_ST	P12931	SRC	Q00535	CDK5	S306	K301N	301	Missense	distal	-5	no	18.794	18.587	EPSD	ICGC	8.808	Down-regulation
CMGC_CDK_CDK5_CDK5_ST	P15927	RPA2	Q00535	CDK5	T21	A17E	17	Missense	distal	-4	no	8.809	9.083	EPSD	ICGC	8.808	Up-regulation
CMGC_CDK_CDK5_CDK5_ST	P15927	RPA2	Q00535	CDK5	S23	A17E	17	Missense	distal	-6	no	18.395	18.422	EPSD;PhosphoSitePlus	ICGC	8.808	Up-regulation
CMGC_CDK_CDK5_CDK5_ST	O14939	PLD2	Q00535	CDK5	S134	R137L	137	Missense	distal	3	no	18.193	15.723	PhosphoSitePlus	ICGC	8.808	Down-regulation
CMGC_CDK_CDK5_CDK5_ST	O14939	PLD2	Q00535	CDK5	S134	A130T	130	Missense	distal	-4	no	18.193	18.593	PhosphoSitePlus	ICGC	8.808	Up-regulation
CMGC_CDK_CDK5_CDK5_ST	O14939	PLD2	Q00535	CDK5	S484	P489L	489	Missense	distal	5	no	10.070	9.897	EPSD	ICGC;COSMIC	8.808	Down-regulation
CMGC_CDK_CDK5_CDK5_ST	O14939	PLD2	Q00535	CDK5	S484	P489S	489	Missense	distal	5	no	10.070	10.082	EPSD	ICGC;COSMIC;GDSC;CCLE	8.808	Up-regulation
CMGC_CDK_CDK5_CDK5_ST	O14939	PLD2	Q00535	CDK5	T488	P489L	489	Missense	proximal	1	no	18.659	6.709	EPSD	ICGC;COSMIC	8.808	Loss
CMGC_CDK_CDK5_CDK5_ST	O14939	PLD2	Q00535	CDK5	T488	P489S	489	Missense	proximal	1	no	18.659	6.758	EPSD	ICGC;COSMIC;GDSC;CCLE	8.808	Loss
CMGC_CDK_CDK5_CDK5_ST	O14939	PLD2	Q00535	CDK5	S493	P489L	489	Missense	distal	-4	no	19.277	18.804	EPSD	ICGC;COSMIC	8.808	Down-regulation
CMGC_CDK_CDK5_CDK5_ST	O14939	PLD2	Q00535	CDK5	S493	P489S	489	Missense	distal	-4	no	19.277	19.623	EPSD	ICGC;COSMIC;GDSC;CCLE	8.808	Up-regulation
CMGC_CDK_CDK5_CDK5_ST	O14939	PLD2	Q00535	CDK5	T496	P489L	489	Missense	distal	-7	no	16.454	16.402	EPSD	ICGC;COSMIC	8.808	Down-regulation
CMGC_CDK_CDK5_CDK5_ST	O14939	PLD2	Q00535	CDK5	T496	P489S	489	Missense	distal	-7	no	16.454	16.458	EPSD	ICGC;COSMIC;GDSC;CCLE	8.808	Up-regulation
CMGC_CDK_CDK5_CDK5_ST	O14939	PLD2	Q00535	CDK5	T575	Y580H	580	Missense	distal	5	no	16.231	16.368	EPSD	ICGC;COSMIC	8.808	Up-regulation
CMGC_CDK_CDK5_CDK5_ST	O14939	PLD2	Q00535	CDK5	T575	T577I	577	Missense	proximal	2	no	16.231	16.136	EPSD	ICGC;COSMIC	8.808	Down-regulation
CMGC_CDK_CDK5_CDK5_ST	O14939	PLD2	Q00535	CDK5	T575	P576S	576	Missense	proximal	1	no	16.231	4.330	EPSD	ICGC;COSMIC	8.808	Loss
CMGC_CDK_CDK5_CDK5_ST	O14939	PLD2	Q00535	CDK5	S888	S894C	894	Missense	distal	6	no	17.217	17.200	EPSD	ICGC	8.808	Down-regulation
CMGC_CDK_CDK5_CDK5_ST	Q05397	PTK2	Q00535	CDK5	T13	D7G	7	Missense	distal	-6	no	18.075	18.077	EPSD	ICGC;COSMIC	8.808	Up-regulation
CMGC_CDK_CDK5_CDK5_ST	Q05397	PTK2	Q00535	CDK5	T13	L6V	6	Missense	distal	-7	no	18.075	18.113	EPSD	ICGC;COSMIC	8.808	Up-regulation
CMGC_CDK_CDK5_CDK5_ST	Q05397	PTK2	Q00535	CDK5	T13	S17Y	17	Missense	distal	4	no	18.075	17.990	EPSD	ICGC;COSMIC	8.808	Down-regulation
CMGC_CDK_CDK5_CDK5_ST	Q05397	PTK2	Q00535	CDK5	S17	S17Y	17	Missense	central	0	yes	9.267	0.000	EPSD	ICGC;COSMIC	8.808	Loss
CMGC_CDK_CDK5_CDK5_ST	Q05397	PTK2	Q00535	CDK5	S29	R28S	28	Missense	proximal	-1	no	17.967	17.968	EPSD	ICGC	8.808	Up-regulation
CMGC_CDK_CDK5_CDK5_ST	Q05397	PTK2	Q00535	CDK5	S29	R28C	28	Missense	proximal	-1	no	17.967	17.961	EPSD	ICGC;COSMIC	8.808	Down-regulation
CMGC_CDK_CDK5_CDK5_ST	Q05397	PTK2	Q00535	CDK5	S248	R252I	252	Missense	distal	4	no	15.944	15.884	EPSD	ICGC;COSMIC	8.808	Down-regulation
CMGC_CDK_CDK5_CDK5_ST	Q05397	PTK2	Q00535	CDK5	S248	Y251H	251	Missense	distal	3	no	15.944	17.112	EPSD	ICGC	8.808	Up-regulation
CMGC_CDK_CDK5_CDK5_ST	Q05397	PTK2	Q00535	CDK5	S443	L449F	449	Missense	distal	6	no	16.344	16.339	EPSD	ICGC	8.808	Down-regulation
CMGC_CDK_CDK5_CDK5_ST	Q05397	PTK2	Q00535	CDK5	S443	H437N	437	Missense	distal	-6	no	16.344	16.345	EPSD	ICGC	8.808	Up-regulation
CMGC_CDK_CDK5_CDK5_ST	Q05397	PTK2	Q00535	CDK5	S716	P723Q	723	Missense	distal	7	no	8.899	8.895	EPSD	ICGC	8.808	Down-regulation
CMGC_CDK_CDK5_CDK5_ST	Q05397	PTK2	Q00535	CDK5	S722	P723Q	723	Missense	proximal	1	no	17.684	8.708	EPSD	ICGC	8.808	Loss
CMGC_CDK_CDK5_CDK5_ST	Q05397	PTK2	Q00535	CDK5	S722	E727K	727	Missense	distal	5	no	17.684	17.935	EPSD	ICGC;COSMIC	8.808	Up-regulation
CMGC_CDK_CDK5_CDK5_ST	Q05397	PTK2	Q00535	CDK5	S732	E727K	727	Missense	distal	-5	no	17.875	18.165	EPSD	ICGC;COSMIC	8.808	Up-regulation
CMGC_CDK_CDK5_CDK5_ST	Q05397	PTK2	Q00535	CDK5	S840	L839I	839	Missense	proximal	-1	no	8.909	8.912	EPSD	ICGC	8.808	Up-regulation
CMGC_CDK_CDK5_CDK5_ST	Q05397	PTK2	Q00535	CDK5	S893	S897Y	897	Missense	distal	4	no	16.233	16.148	EPSD	ICGC	8.808	Down-regulation
CMGC_CDK_CDK5_CDK5_ST	Q05397	PTK2	Q00535	CDK5	S893	S897N	897	Missense	distal	4	no	16.233	16.203	EPSD	ICGC;COSMIC	8.808	Down-regulation
CMGC_CDK_CDK5_CDK5_ST	Q05397	PTK2	Q00535	CDK5	S893	S897C	897	Missense	distal	4	no	16.233	16.142	EPSD	ICGC	8.808	Down-regulation
CMGC_CDK_CDK5_CDK5_ST	P10275	AR	Q00535	CDK5	S96	E93K	93	Missense	distal	-3	no	17.005	17.078	EPSD	ICGC	8.808	Up-regulation
CMGC_CDK_CDK5_CDK5_ST	P10275	AR	Q00535	CDK5	S258	G260V	260	Missense	proximal	2	no	15.761	15.822	EPSD	ICGC;COSMIC	8.808	Up-regulation
CMGC_CDK_CDK5_CDK5_ST	P10275	AR	Q00535	CDK5	T282	A288T	288	Missense	distal	6	no	17.057	17.070	EPSD	ICGC;COSMIC	8.808	Up-regulation
CMGC_CDK_CDK5_CDK5_ST	P10275	AR	Q00535	CDK5	T282	R280L	280	Missense	proximal	-2	no	17.057	16.697	EPSD	ICGC	8.808	Down-regulation
CMGC_CDK_CDK5_CDK5_ST	P10275	AR	Q00535	CDK5	T282	A288D	288	Missense	distal	6	no	17.057	17.059	EPSD	ICGC;COSMIC	8.808	Up-regulation
CMGC_CDK_CDK5_CDK5_ST	P10275	AR	Q00535	CDK5	S298	A299V	299	Missense	proximal	1	no	8.738	8.854	EPSD	ICGC	8.808	Gain
CMGC_CDK_CDK5_CDK5_ST	P10275	AR	Q00535	CDK5	S310	T317A	317	Missense	distal	7	no	19.095	19.086	PhosphoSitePlus;EPSD	ICGC;COSMIC	8.808	Down-regulation
CMGC_CDK_CDK5_CDK5_ST	P10275	AR	Q00535	CDK5	S310	T303S	303	Missense	distal	-7	no	19.095	19.109	PhosphoSitePlus;EPSD	ICGC;COSMIC	8.808	Up-regulation
CMGC_CDK_CDK5_CDK5_ST	P10275	AR	Q00535	CDK5	S310	G314R	314	Missense	distal	4	no	19.095	19.163	PhosphoSitePlus;EPSD	ICGC	8.808	Up-regulation
CMGC_CDK_CDK5_CDK5_ST	P10275	AR	Q00535	CDK5	S516	Y514H	514	Missense	proximal	-2	no	17.169	17.381	EPSD	ICGC;GDSC;CCLE	8.808	Up-regulation
CMGC_CDK_CDK5_CDK5_ST	P10275	AR	Q00535	CDK5	S516	S516I	516	Missense	central	0	yes	17.169	0.000	EPSD	ICGC	8.808	Loss
CMGC_CDK_CDK5_CDK5_ST	P10275	AR	Q00535	CDK5	S516	V509L	509	Missense	distal	-7	no	17.169	17.131	EPSD	ICGC;COSMIC	8.808	Down-regulation
CMGC_CDK_CDK5_CDK5_ST	O94811	TPPP	Q00535	CDK5	T14	T14K	14	Missense	central	0	yes	20.417	0.000	EPSD;PhosphoSitePlus	ICGC;COSMIC	8.808	Loss
CMGC_CDK_CDK5_CDK5_ST	O94811	TPPP	Q00535	CDK5	S18	D21E	21	Missense	distal	3	no	19.174	19.239	EPSD;PhosphoSitePlus	ICGC	8.808	Up-regulation
CMGC_CDK_CDK5_CDK5_ST	O94811	TPPP	Q00535	CDK5	S18	T14K	14	Missense	distal	-4	no	19.174	19.551	EPSD;PhosphoSitePlus	ICGC;COSMIC	8.808	Up-regulation
CMGC_CDK_CDK5_CDK5_ST	O94811	TPPP	Q00535	CDK5	S18	P22L	22	Missense	distal	4	no	19.174	19.092	EPSD;PhosphoSitePlus	ICGC	8.808	Down-regulation
CMGC_CDK_CDK5_CDK5_ST	O94811	TPPP	Q00535	CDK5	S45	A44T	44	Missense	proximal	-1	no	15.499	15.503	EPSD	ICGC;COSMIC;GDSC;CCLE	8.808	Up-regulation
CMGC_CDK_CDK5_CDK5_ST	O94811	TPPP	Q00535	CDK5	S45	A44V	44	Missense	proximal	-1	no	15.499	15.502	EPSD	ICGC	8.808	Up-regulation
CMGC_CDK_CDK5_CDK5_ST	O94811	TPPP	Q00535	CDK5	S160	V154G	154	Missense	distal	-6	no	18.510	18.460	PhosphoSitePlus;EPSD	ICGC;COSMIC	8.808	Down-regulation
CMGC_CDK_CDK5_CDK5_ST	Q9Y210	TRPC6	Q00535	CDK5	S4	Q3H	3	Missense	proximal	-1	no	16.867	16.866	EPSD	ICGC;COSMIC	8.808	Down-regulation
CMGC_CDK_CDK5_CDK5_ST	Q9Y210	TRPC6	Q00535	CDK5	S13	A18V	18	Missense	distal	5	no	9.389	9.486	EPSD	ICGC;COSMIC	8.808	Up-regulation
CMGC_CDK_CDK5_CDK5_ST	Q9Y210	TRPC6	Q00535	CDK5	S13	P15S	15	Missense	proximal	2	no	9.389	9.372	EPSD	ICGC;COSMIC	8.808	Down-regulation
CMGC_CDK_CDK5_CDK5_ST	Q9Y210	TRPC6	Q00535	CDK5	S13	R16W	16	Missense	distal	3	no	9.389	7.699	EPSD	ICGC;COSMIC	8.808	Loss
CMGC_CDK_CDK5_CDK5_ST	Q9Y210	TRPC6	Q00535	CDK5	S13	G20R	20	Missense	distal	7	no	9.389	9.401	EPSD	ICGC;COSMIC	8.808	Up-regulation
CMGC_CDK_CDK5_CDK5_ST	Q9Y210	TRPC6	Q00535	CDK5	S14	A18V	18	Missense	distal	4	no	19.579	19.622	PhosphoSitePlus	ICGC;COSMIC	8.808	Up-regulation
CMGC_CDK_CDK5_CDK5_ST	Q9Y210	TRPC6	Q00535	CDK5	S14	P15S	15	Missense	proximal	1	no	19.579	7.678	PhosphoSitePlus	ICGC;COSMIC	8.808	Loss
CMGC_CDK_CDK5_CDK5_ST	Q9Y210	TRPC6	Q00535	CDK5	S14	R16W	16	Missense	proximal	2	no	19.579	19.387	PhosphoSitePlus	ICGC;COSMIC	8.808	Down-regulation
CMGC_CDK_CDK5_CDK5_ST	Q9Y210	TRPC6	Q00535	CDK5	S14	G20R	20	Missense	distal	6	no	19.579	19.596	PhosphoSitePlus	ICGC;COSMIC	8.808	Up-regulation
CMGC_CDK_CDK5_CDK5_ST	Q9Y210	TRPC6	Q00535	CDK5	S195	S197R	197	Missense	proximal	2	no	17.799	17.898	EPSD	ICGC;COSMIC	8.808	Up-regulation
CMGC_CDK_CDK5_CDK5_ST	Q9Y210	TRPC6	Q00535	CDK5	S195	S199F	199	Missense	distal	4	no	17.799	17.687	EPSD	ICGC	8.808	Down-regulation
CMGC_CDK_CDK5_CDK5_ST	Q9Y210	TRPC6	Q00535	CDK5	S270	N275D	275	Missense	distal	5	no	11.090	11.021	EPSD	ICGC;COSMIC	8.808	Down-regulation
CMGC_CDK_CDK5_CDK5_ST	Q9Y210	TRPC6	Q00535	CDK5	S270	S270Y	270	Missense	central	0	yes	11.090	0.000	EPSD	ICGC;COSMIC	8.808	Loss
CMGC_CDK_CDK5_CDK5_ST	Q9Y210	TRPC6	Q00535	CDK5	S272	N275D	275	Missense	distal	3	no	9.508	9.089	EPSD	ICGC;COSMIC	8.808	Down-regulation
CMGC_CDK_CDK5_CDK5_ST	Q9Y210	TRPC6	Q00535	CDK5	S272	S270Y	270	Missense	proximal	-2	no	9.508	9.079	EPSD	ICGC;COSMIC	8.808	Down-regulation
CMGC_CDK_CDK5_CDK5_ST	Q9Y210	TRPC6	Q00535	CDK5	S282	N275D	275	Missense	distal	-7	no	17.661	17.643	EPSD	ICGC;COSMIC	8.808	Down-regulation
CMGC_CDK_CDK5_CDK5_ST	Q9Y210	TRPC6	Q00535	CDK5	S282	A284D	284	Missense	proximal	2	no	17.661	17.649	EPSD	ICGC;COSMIC	8.808	Down-regulation
CMGC_CDK_CDK5_CDK5_ST	Q9Y210	TRPC6	Q00535	CDK5	S282	S289Y	289	Missense	distal	7	no	17.661	17.648	EPSD	ICGC	8.808	Down-regulation
CMGC_CDK_CDK5_CDK5_ST	Q9Y210	TRPC6	Q00535	CDK5	S769	Y775C	775	Missense	distal	6	no	17.871	17.869	EPSD	ICGC;COSMIC	8.808	Down-regulation
CMGC_CDK_CDK5_CDK5_ST	Q9Y210	TRPC6	Q00535	CDK5	S769	P770L	770	Missense	proximal	1	no	17.871	5.922	EPSD	ICGC	8.808	Loss
CMGC_CDK_CDK5_CDK5_ST	Q9Y210	TRPC6	Q00535	CDK5	S769	P770Q	770	Missense	proximal	1	no	17.871	8.895	EPSD	ICGC;COSMIC	8.808	Down-regulation
CMGC_CDK_CDK5_CDK5_ST	Q9Y210	TRPC6	Q00535	CDK5	S903	T906K	906	Missense	distal	3	no	8.427	9.609	EPSD	ICGC	8.808	Gain
CMGC_CDK_CDK5_CDK5_ST	Q9NXR1	NDE1	Q00535	CDK5	T215	H219N	219	Missense	distal	4	no	17.185	17.178	EPSD	ICGC;COSMIC	8.808	Down-regulation
CMGC_CDK_CDK5_CDK5_ST	Q9NXR1	NDE1	Q00535	CDK5	S333	P334L	334	Missense	proximal	1	no	17.849	5.899	EPSD	ICGC	8.808	Loss
CMGC_CDK_CDK5_CDK5_ST	Q9NXR1	NDE1	Q00535	CDK5	S333	S337L	337	Missense	distal	4	no	17.849	17.766	EPSD	ICGC	8.808	Down-regulation
CMGC_CDK_CDK5_CDK5_ST	Q9NXR1	NDE1	Q00535	CDK5	S333	S333L	333	Missense	central	0	yes	17.849	0.000	EPSD	ICGC	8.808	Loss
CMGC_CDK_CDK5_CDK5_ST	Q9NXR1	NDE1	Q00535	CDK5	S333	S331L	331	Missense	proximal	-2	no	17.849	17.533	EPSD	ICGC	8.808	Down-regulation
CMGC_CDK_CDK5_CDK5_ST	P04637	TP53	Q00535	CDK5	S15	E11K	11	Missense	distal	-4	no	11.612	12.114	EPSD;PhosphoSitePlus	ICGC;COSMIC	8.808	Up-regulation
CMGC_CDK_CDK5_CDK5_ST	P04637	TP53	Q00535	CDK5	S33	P34L	34	Missense	proximal	1	no	17.666	5.716	EPSD;PhosphoSitePlus	ICGC;COSMIC	8.808	Loss
CMGC_CDK_CDK5_CDK5_ST	P04637	TP53	Q00535	CDK5	S33	S33F	33	Missense	central	0	yes	17.666	0.000	EPSD;PhosphoSitePlus	ICGC;COSMIC	8.808	Loss
CMGC_CDK_CDK5_CDK5_ST	P04637	TP53	Q00535	CDK5	S33	N30I	30	Missense	distal	-3	no	17.666	17.660	EPSD;PhosphoSitePlus	ICGC	8.808	Down-regulation
CMGC_CDK_CDK5_CDK5_ST	P04637	TP53	Q00535	CDK5	S46	D48G	48	Missense	proximal	2	no	17.016	17.048	PhosphoSitePlus;EPSD	ICGC;COSMIC	8.808	Up-regulation
CMGC_CDK_CDK5_CDK5_ST	P04637	TP53	Q00535	CDK5	S46	Q52K	52	Missense	distal	6	no	17.016	17.028	PhosphoSitePlus;EPSD	ICGC	8.808	Up-regulation
CMGC_CDK_CDK5_CDK5_ST	P04637	TP53	Q00535	CDK5	T81	A88D	88	Missense	distal	7	no	16.829	16.830	EPSD	ICGC	8.808	Up-regulation
CMGC_CDK_CDK5_CDK5_ST	P04637	TP53	Q00535	CDK5	T81	P87Q	87	Missense	distal	6	no	16.829	16.826	EPSD	ICGC;COSMIC	8.808	Down-regulation
CMGC_CDK_CDK5_CDK5_ST	P04637	TP53	Q00535	CDK5	S99	Q100K	100	Missense	proximal	1	no	10.461	1.259	EPSD	ICGC;COSMIC	8.808	Loss
CMGC_CDK_CDK5_CDK5_ST	P04637	TP53	Q00535	CDK5	S99	P92T	92	Missense	distal	-7	no	10.461	10.451	EPSD	ICGC;COSMIC	8.808	Down-regulation
CMGC_CDK_CDK5_CDK5_ST	P04637	TP53	Q00535	CDK5	S99	P92H	92	Missense	distal	-7	no	10.461	10.434	EPSD	ICGC;COSMIC	8.808	Down-regulation
CMGC_CDK_CDK5_CDK5_ST	P04637	TP53	Q00535	CDK5	S99	G105A	105	Missense	distal	6	no	10.461	10.459	EPSD	ICGC;COSMIC	8.808	Down-regulation
CMGC_CDK_CDK5_CDK5_ST	P04637	TP53	Q00535	CDK5	S127	T125R	125	Missense	proximal	-2	no	16.799	16.884	EPSD	ICGC;COSMIC	8.808	Up-regulation
CMGC_CDK_CDK5_CDK5_ST	P04637	TP53	Q00535	CDK5	S127	F134C	134	Missense	distal	7	no	16.799	16.802	EPSD	ICGC;COSMIC;CCLE	8.808	Up-regulation
CMGC_CDK_CDK5_CDK5_ST	P04637	TP53	Q00535	CDK5	S127	C124G	124	Missense	distal	-3	no	16.799	16.822	EPSD	ICGC;COSMIC	8.808	Up-regulation
CMGC_CDK_CDK5_CDK5_ST	P04637	TP53	Q00535	CDK5	S127	C124R	124	Missense	distal	-3	no	16.799	16.877	EPSD	ICGC;COSMIC;GDSC;CCLE	8.808	Up-regulation
CMGC_CDK_CDK5_CDK5_ST	P04637	TP53	Q00535	CDK5	S127	L130H	130	Missense	distal	3	no	16.799	18.250	EPSD	ICGC;COSMIC	8.808	Up-regulation
CMGC_CDK_CDK5_CDK5_ST	P04637	TP53	Q00535	CDK5	S127	T125A	125	Missense	proximal	-2	no	16.799	16.561	EPSD	ICGC;COSMIC	8.808	Down-regulation
CMGC_CDK_CDK5_CDK5_ST	P04637	TP53	Q00535	CDK5	S127	K120N	120	Missense	distal	-7	no	16.799	16.756	EPSD	ICGC;COSMIC;GDSC;CCLE	8.808	Down-regulation
CMGC_CDK_CDK5_CDK5_ST	P04637	TP53	Q00535	CDK5	S127	N131Y	131	Missense	distal	4	no	16.799	16.745	EPSD	ICGC;COSMIC	8.808	Down-regulation
CMGC_CDK_CDK5_CDK5_ST	P04637	TP53	Q00535	CDK5	S127	K120M	120	Missense	distal	-7	no	16.799	16.710	EPSD	ICGC;COSMIC	8.808	Down-regulation
CMGC_CDK_CDK5_CDK5_ST	P04637	TP53	Q00535	CDK5	S127	K132M	132	Missense	distal	5	no	16.799	16.457	EPSD	ICGC;COSMIC;CCLE	8.808	Down-regulation
CMGC_CDK_CDK5_CDK5_ST	P04637	TP53	Q00535	CDK5	S127	M133T	133	Missense	distal	6	no	16.799	16.816	EPSD	ICGC;COSMIC	8.808	Up-regulation
CMGC_CDK_CDK5_CDK5_ST	P04637	TP53	Q00535	CDK5	S127	K120R	120	Missense	distal	-7	no	16.799	16.782	EPSD	ICGC;COSMIC	8.808	Down-regulation
CMGC_CDK_CDK5_CDK5_ST	P04637	TP53	Q00535	CDK5	S127	C124Y	124	Missense	distal	-3	no	16.799	16.806	EPSD	ICGC;COSMIC	8.808	Up-regulation
CMGC_CDK_CDK5_CDK5_ST	P04637	TP53	Q00535	CDK5	S149	P152R	152	Missense	distal	3	no	7.463	8.861	EPSD	ICGC;COSMIC	8.808	Gain
CMGC_CDK_CDK5_CDK5_ST	P04637	TP53	Q00535	CDK5	T150	R156L	156	Missense	distal	6	no	16.442	16.420	EPSD	ICGC;COSMIC	8.808	Down-regulation
CMGC_CDK_CDK5_CDK5_ST	P04637	TP53	Q00535	CDK5	T150	L145Q	145	Missense	distal	-5	no	16.442	16.581	EPSD	ICGC;COSMIC	8.808	Up-regulation
CMGC_CDK_CDK5_CDK5_ST	P04637	TP53	Q00535	CDK5	T150	P152R	152	Missense	proximal	2	no	16.442	16.524	EPSD	ICGC;COSMIC	8.808	Up-regulation
CMGC_CDK_CDK5_CDK5_ST	P04637	TP53	Q00535	CDK5	T150	G154S	154	Missense	distal	4	no	16.442	16.493	EPSD	ICGC;COSMIC	8.808	Up-regulation
CMGC_CDK_CDK5_CDK5_ST	P04637	TP53	Q00535	CDK5	T150	V157A	157	Missense	distal	7	no	16.442	16.435	EPSD	ICGC;COSMIC	8.808	Down-regulation
CMGC_CDK_CDK5_CDK5_ST	P04637	TP53	Q00535	CDK5	T150	P151F	151	Missense	proximal	1	no	16.442	-5.538	EPSD	ICGC;COSMIC	8.808	Loss
CMGC_CDK_CDK5_CDK5_ST	P04637	TP53	Q00535	CDK5	T150	V147G	147	Missense	distal	-3	no	16.442	16.410	EPSD	ICGC;COSMIC;GDSC;CCLE	8.808	Down-regulation
CMGC_CDK_CDK5_CDK5_ST	P04637	TP53	Q00535	CDK5	T155	R156L	156	Missense	proximal	1	no	10.259	7.257	EPSD	ICGC;COSMIC	8.808	Loss
CMGC_CDK_CDK5_CDK5_ST	P04637	TP53	Q00535	CDK5	T155	P152R	152	Missense	distal	-3	no	10.259	10.268	EPSD	ICGC;COSMIC	8.808	Up-regulation
CMGC_CDK_CDK5_CDK5_ST	P04637	TP53	Q00535	CDK5	T155	G154S	154	Missense	proximal	-1	no	10.259	10.264	EPSD	ICGC;COSMIC	8.808	Up-regulation
CMGC_CDK_CDK5_CDK5_ST	P04637	TP53	Q00535	CDK5	T155	V157A	157	Missense	proximal	2	no	10.259	10.178	EPSD	ICGC;COSMIC	8.808	Down-regulation
CMGC_CDK_CDK5_CDK5_ST	P04637	TP53	Q00535	CDK5	T155	I162S	162	Missense	distal	7	no	10.259	10.266	EPSD	ICGC;COSMIC	8.808	Up-regulation
CMGC_CDK_CDK5_CDK5_ST	P04637	TP53	Q00535	CDK5	T155	P151F	151	Missense	distal	-4	no	10.259	9.444	EPSD	ICGC;COSMIC	8.808	Down-regulation
CMGC_CDK_CDK5_CDK5_ST	P04637	TP53	Q00535	CDK5	T155	M160R	160	Missense	distal	5	no	10.259	10.526	EPSD	ICGC;COSMIC	8.808	Up-regulation
CMGC_CDK_CDK5_CDK5_ST	P04637	TP53	Q00535	CDK5	S315	T312I	312	Missense	distal	-3	no	18.385	18.362	EPSD	ICGC;COSMIC	8.808	Down-regulation
CMGC_CDK_CDK5_CDK5_ST	P04637	TP53	Q00535	CDK5	S315	P322T	322	Missense	distal	7	no	18.385	18.383	EPSD	ICGC	8.808	Down-regulation
CMGC_CDK_CDK5_CDK5_ST	P04637	TP53	Q00535	CDK5	S376	T377P	377	Missense	proximal	1	no	10.348	20.835	EPSD	ICGC;COSMIC	8.808	Up-regulation
CMGC_CDK_CDK5_CDK5_ST	P04637	TP53	Q00535	CDK5	S376	G374C	374	Missense	proximal	-2	no	10.348	10.241	EPSD	ICGC;COSMIC	8.808	Down-regulation
CMGC_CDK_CDK5_CDK5_ST	P04637	TP53	Q00535	CDK5	S376	R379S	379	Missense	distal	3	no	10.348	8.930	EPSD	ICGC	8.808	Down-regulation
CMGC_CDK_CDK5_CDK5_ST	P04637	TP53	Q00535	CDK5	S376	R379C	379	Missense	distal	3	no	10.348	8.052	EPSD	ICGC;COSMIC	8.808	Loss
CMGC_CDK_CDK5_CDK5_ST	P04637	TP53	Q00535	CDK5	S378	F385L	385	Missense	distal	7	no	11.670	11.676	EPSD	ICGC;COSMIC	8.808	Up-regulation
CMGC_CDK_CDK5_CDK5_ST	P04637	TP53	Q00535	CDK5	S378	G374C	374	Missense	distal	-4	no	11.670	11.487	EPSD	ICGC;COSMIC	8.808	Down-regulation
CMGC_CDK_CDK5_CDK5_ST	P04637	TP53	Q00535	CDK5	S378	R379S	379	Missense	proximal	1	no	11.670	8.716	EPSD	ICGC	8.808	Loss
CMGC_CDK_CDK5_CDK5_ST	P04637	TP53	Q00535	CDK5	S378	R379C	379	Missense	proximal	1	no	11.670	-0.056	EPSD	ICGC;COSMIC	8.808	Loss
CMGC_CDK_CDK5_CDK5_ST	Q99490	AGAP2	Q00535	CDK5	S140	R141P	141	Missense	proximal	1	no	9.318	18.265	EPSD	ICGC	8.808	Up-regulation
CMGC_CDK_CDK5_CDK5_ST	Q99490	AGAP2	Q00535	CDK5	S140	S147C	147	Missense	distal	7	no	9.318	9.303	EPSD	ICGC;COSMIC	8.808	Down-regulation
CMGC_CDK_CDK5_CDK5_ST	Q99490	AGAP2	Q00535	CDK5	S147	R141P	141	Missense	distal	-6	no	17.302	17.257	EPSD	ICGC	8.808	Down-regulation
CMGC_CDK_CDK5_CDK5_ST	Q99490	AGAP2	Q00535	CDK5	S147	S147C	147	Missense	central	0	yes	17.302	0.000	EPSD	ICGC;COSMIC	8.808	Loss
CMGC_CDK_CDK5_CDK5_ST	Q99490	AGAP2	Q00535	CDK5	S267	R269W	269	Missense	proximal	2	no	20.291	20.100	EPSD	ICGC;COSMIC	8.808	Down-regulation
CMGC_CDK_CDK5_CDK5_ST	Q99490	AGAP2	Q00535	CDK5	S267	R269L	269	Missense	proximal	2	no	20.291	20.044	EPSD	ICGC;COSMIC	8.808	Down-regulation
CMGC_CDK_CDK5_CDK5_ST	Q99490	AGAP2	Q00535	CDK5	T812	S818R	818	Missense	distal	6	no	16.822	16.829	EPSD	ICGC	8.808	Up-regulation
CMGC_CDK_CDK5_CDK5_ST	Q99490	AGAP2	Q00535	CDK5	S818	S818R	818	Missense	central	0	yes	17.622	0.000	EPSD	ICGC	8.808	Loss
CMGC_CDK_CDK5_CDK5_ST	O15516	CLOCK	Q00535	CDK5	S427	S427R	427	Missense	central	0	yes	17.450	0.000	EPSD	ICGC	8.808	Loss
CMGC_CDK_CDK5_CDK5_ST	O15516	CLOCK	Q00535	CDK5	S427	P428R	428	Missense	proximal	1	no	17.450	8.503	EPSD	ICGC;COSMIC	8.808	Loss
CMGC_CDK_CDK5_CDK5_ST	O15516	CLOCK	Q00535	CDK5	T429	S427R	427	Missense	proximal	-2	no	16.361	16.405	EPSD	ICGC	8.808	Up-regulation
CMGC_CDK_CDK5_CDK5_ST	O15516	CLOCK	Q00535	CDK5	T429	P428R	428	Missense	proximal	-1	no	16.361	16.362	EPSD	ICGC;COSMIC	8.808	Up-regulation
CMGC_CDK_CDK5_CDK5_ST	O15516	CLOCK	Q00535	CDK5	T429	R435L	435	Missense	distal	6	no	16.361	16.339	EPSD	ICGC;COSMIC	8.808	Down-regulation
CMGC_CDK_CDK5_CDK5_ST	O15516	CLOCK	Q00535	CDK5	S437	R435L	435	Missense	proximal	-2	no	9.628	9.267	EPSD	ICGC;COSMIC	8.808	Down-regulation
CMGC_CDK_CDK5_CDK5_ST	O15516	CLOCK	Q00535	CDK5	S450	T453N	453	Missense	distal	3	no	8.859	8.108	EPSD	ICGC	8.808	Loss
CMGC_CDK_CDK5_CDK5_ST	O15516	CLOCK	Q00535	CDK5	S450	P456L	456	Missense	distal	6	no	8.859	8.845	EPSD	ICGC;COSMIC	8.808	Down-regulation
CMGC_CDK_CDK5_CDK5_ST	O15516	CLOCK	Q00535	CDK5	T451	T453N	453	Missense	proximal	2	no	19.355	19.284	PhosphoSitePlus;EPSD	ICGC	8.808	Down-regulation
CMGC_CDK_CDK5_CDK5_ST	O15516	CLOCK	Q00535	CDK5	T451	D458Y	458	Missense	distal	7	no	19.355	19.350	PhosphoSitePlus;EPSD	ICGC	8.808	Down-regulation
CMGC_CDK_CDK5_CDK5_ST	O15516	CLOCK	Q00535	CDK5	T451	P456L	456	Missense	distal	5	no	19.355	19.182	PhosphoSitePlus;EPSD	ICGC;COSMIC	8.808	Down-regulation
CMGC_CDK_CDK5_CDK5_ST	O15516	CLOCK	Q00535	CDK5	T461	P463T	463	Missense	proximal	2	no	18.112	18.119	EPSD;PhosphoSitePlus	ICGC;COSMIC	8.808	Up-regulation
CMGC_CDK_CDK5_CDK5_ST	O15516	CLOCK	Q00535	CDK5	T461	T459K	459	Missense	proximal	-2	no	18.112	18.223	EPSD;PhosphoSitePlus	ICGC;COSMIC	8.808	Up-regulation
CMGC_CDK_CDK5_CDK5_ST	O15516	CLOCK	Q00535	CDK5	T461	P468T	468	Missense	distal	7	no	18.112	18.111	EPSD;PhosphoSitePlus	ICGC;COSMIC	8.808	Down-regulation
CMGC_CDK_CDK5_CDK5_ST	O15516	CLOCK	Q00535	CDK5	T461	H466L	466	Missense	distal	5	no	18.112	17.968	EPSD;PhosphoSitePlus	ICGC;COSMIC	8.808	Down-regulation
CMGC_CDK_CDK5_CDK5_ST	O15516	CLOCK	Q00535	CDK5	T461	D458Y	458	Missense	distal	-3	no	18.112	18.096	EPSD;PhosphoSitePlus	ICGC	8.808	Down-regulation
CMGC_CDK_CDK5_CDK5_ST	O15516	CLOCK	Q00535	CDK5	T461	P456L	456	Missense	distal	-5	no	18.112	17.915	EPSD;PhosphoSitePlus	ICGC;COSMIC	8.808	Down-regulation
CMGC_CDK_CDK5_CDK5_ST	Q14194	CRMP1	Q00535	CDK5	S304	V302M	302	Missense	proximal	-2	no	17.133	16.741	EPSD	ICGC;COSMIC	8.808	Down-regulation
CMGC_CDK_CDK5_CDK5_ST	Q14194	CRMP1	Q00535	CDK5	S304	A300V	300	Missense	distal	-4	no	17.133	17.552	EPSD	ICGC;COSMIC	8.808	Up-regulation
CMGC_CDK_CDK5_CDK5_ST	Q14194	CRMP1	Q00535	CDK5	S304	S308N	308	Missense	distal	4	no	17.133	17.102	EPSD	ICGC;COSMIC	8.808	Down-regulation
CMGC_CDK_CDK5_CDK5_ST	Q14194	CRMP1	Q00535	CDK5	S304	A299E	299	Missense	distal	-5	no	17.133	17.140	EPSD	ICGC;COSMIC	8.808	Up-regulation
CMGC_CDK_CDK5_CDK5_ST	Q14194	CRMP1	Q00535	CDK5	S304	A299T	299	Missense	distal	-5	no	17.133	17.289	EPSD	ICGC;COSMIC	8.808	Up-regulation
CMGC_CDK_CDK5_CDK5_ST	Q14194	CRMP1	Q00535	CDK5	S304	A299V	299	Missense	distal	-5	no	17.133	17.258	EPSD	ICGC	8.808	Up-regulation
CMGC_CDK_CDK5_CDK5_ST	Q14194	CRMP1	Q00535	CDK5	S308	V302M	302	Missense	distal	-6	no	18.518	18.414	EPSD	ICGC;COSMIC	8.808	Down-regulation
CMGC_CDK_CDK5_CDK5_ST	Q14194	CRMP1	Q00535	CDK5	S308	S308N	308	Missense	central	0	yes	18.518	0.000	EPSD	ICGC;COSMIC	8.808	Loss
CMGC_CDK_CDK5_CDK5_ST	Q14194	CRMP1	Q00535	CDK5	S308	T312N	312	Missense	distal	4	no	18.518	18.490	EPSD	ICGC	8.808	Down-regulation
CMGC_CDK_CDK5_CDK5_ST	Q14194	CRMP1	Q00535	CDK5	S522	P528H	528	Missense	distal	6	no	20.485	20.482	EPSD;PhosphoSitePlus	ICGC	8.808	Down-regulation
CMGC_CDK_CDK5_CDK5_ST	P35612	ADD2	Q00535	CDK5	S11	T5M	5	Missense	distal	-6	no	19.042	18.921	EPSD	ICGC;COSMIC;CCLE	8.808	Down-regulation
CMGC_CDK_CDK5_CDK5_ST	P35612	ADD2	Q00535	CDK5	S11	P13L	13	Missense	proximal	2	no	19.042	18.877	EPSD	ICGC;COSMIC	8.808	Down-regulation
CMGC_CDK_CDK5_CDK5_ST	P35612	ADD2	Q00535	CDK5	S11	A10D	10	Missense	proximal	-1	no	19.042	19.043	EPSD	ICGC;COSMIC	8.808	Up-regulation
CMGC_CDK_CDK5_CDK5_ST	P35612	ADD2	Q00535	CDK5	S11	A9V	9	Missense	proximal	-2	no	19.042	19.238	EPSD	ICGC;GDSC	8.808	Up-regulation
CMGC_CDK_CDK5_CDK5_ST	P35612	ADD2	Q00535	CDK5	S60	E65Q	65	Missense	distal	5	no	15.928	15.979	EPSD	ICGC;COSMIC	8.808	Up-regulation
CMGC_CDK_CDK5_CDK5_ST	P35612	ADD2	Q00535	CDK5	S60	R53H	53	Missense	distal	-7	no	15.928	15.897	EPSD	ICGC;COSMIC	8.808	Down-regulation
CMGC_CDK_CDK5_CDK5_ST	P35612	ADD2	Q00535	CDK5	S60	E66K	66	Missense	distal	6	no	15.928	15.947	EPSD	ICGC	8.808	Up-regulation
CMGC_CDK_CDK5_CDK5_ST	P35612	ADD2	Q00535	CDK5	S60	M56V	56	Missense	distal	-4	no	15.928	16.516	EPSD	ICGC;COSMIC	8.808	Up-regulation
CMGC_CDK_CDK5_CDK5_ST	P35612	ADD2	Q00535	CDK5	S60	L58Q	58	Missense	proximal	-2	no	15.928	16.152	EPSD	ICGC;COSMIC	8.808	Up-regulation
CMGC_CDK_CDK5_CDK5_ST	P35612	ADD2	Q00535	CDK5	T436	R432C	432	Missense	distal	-4	no	17.896	17.333	EPSD	ICGC;COSMIC	8.808	Down-regulation
CMGC_CDK_CDK5_CDK5_ST	P35612	ADD2	Q00535	CDK5	T436	R442Q	442	Missense	distal	6	no	17.896	17.885	EPSD	ICGC;COSMIC	8.808	Down-regulation
CMGC_CDK_CDK5_CDK5_ST	P35612	ADD2	Q00535	CDK5	T436	E429D	429	Missense	distal	-7	no	17.896	17.898	EPSD	ICGC;COSMIC	8.808	Up-regulation
CMGC_CDK_CDK5_CDK5_ST	P35612	ADD2	Q00535	CDK5	S455	T461M	461	Missense	distal	6	no	17.512	17.495	EPSD	ICGC;COSMIC	8.808	Down-regulation
CMGC_CDK_CDK5_CDK5_ST	P35612	ADD2	Q00535	CDK5	S455	P458H	458	Missense	distal	3	no	17.512	17.891	EPSD	ICGC;COSMIC	8.808	Up-regulation
CMGC_CDK_CDK5_CDK5_ST	P35612	ADD2	Q00535	CDK5	S455	S452R	452	Missense	distal	-3	no	17.512	17.527	EPSD	ICGC	8.808	Up-regulation
CMGC_CDK_CDK5_CDK5_ST	P35612	ADD2	Q00535	CDK5	S455	T460N	460	Missense	distal	5	no	17.512	17.449	EPSD	ICGC	8.808	Down-regulation
CMGC_CDK_CDK5_CDK5_ST	P35612	ADD2	Q00535	CDK5	S530	R529Q	529	Missense	proximal	-1	no	17.904	17.902	EPSD	ICGC;COSMIC	8.808	Down-regulation
CMGC_CDK_CDK5_CDK5_ST	P35612	ADD2	Q00535	CDK5	S592	P587S	587	Missense	distal	-5	no	19.175	19.198	EPSD	ICGC;COSMIC	8.808	Up-regulation
CMGC_CDK_CDK5_CDK5_ST	P35612	ADD2	Q00535	CDK5	S592	P593H	593	Missense	proximal	1	no	19.175	0.663	EPSD	ICGC	8.808	Loss
CMGC_CDK_CDK5_CDK5_ST	P35612	ADD2	Q00535	CDK5	S600	P593H	593	Missense	distal	-7	no	17.846	17.820	EPSD	ICGC	8.808	Down-regulation
CMGC_CDK_CDK5_CDK5_ST	P35612	ADD2	Q00535	CDK5	S604	A609S	609	Missense	distal	5	no	19.529	19.663	EPSD;PhosphoSitePlus	ICGC;COSMIC	8.808	Up-regulation
CMGC_CDK_CDK5_CDK5_ST	P35612	ADD2	Q00535	CDK5	S613	A609S	609	Missense	distal	-4	no	17.339	18.241	EPSD	ICGC;COSMIC	8.808	Up-regulation
CMGC_CDK_CDK5_CDK5_ST	P35612	ADD2	Q00535	CDK5	S613	P614R	614	Missense	proximal	1	no	17.339	8.392	EPSD	ICGC	8.808	Loss
CMGC_CDK_CDK5_CDK5_ST	P35612	ADD2	Q00535	CDK5	S613	K612E	612	Missense	proximal	-1	no	17.339	17.334	EPSD	ICGC	8.808	Down-regulation
CMGC_CDK_CDK5_CDK5_ST	P35612	ADD2	Q00535	CDK5	S617	P614R	614	Missense	distal	-3	no	19.900	19.909	EPSD;PhosphoSitePlus	ICGC	8.808	Up-regulation
CMGC_CDK_CDK5_CDK5_ST	P35612	ADD2	Q00535	CDK5	S617	K612E	612	Missense	distal	-5	no	19.900	19.610	EPSD;PhosphoSitePlus	ICGC	8.808	Down-regulation
CMGC_CDK_CDK5_CDK5_ST	P35612	ADD2	Q00535	CDK5	S617	S621C	621	Missense	distal	4	no	19.900	19.809	EPSD;PhosphoSitePlus	ICGC	8.808	Down-regulation
CMGC_CDK_CDK5_CDK5_ST	P35612	ADD2	Q00535	CDK5	S667	M669I	669	Missense	proximal	2	no	9.069	9.173	EPSD	ICGC	8.808	Up-regulation
CMGC_CDK_CDK5_CDK5_ST	P35612	ADD2	Q00535	CDK5	S667	S663R	663	Missense	distal	-4	no	9.069	8.608	EPSD	ICGC	8.808	Loss
CMGC_CDK_CDK5_CDK5_ST	P35612	ADD2	Q00535	CDK5	S693	P698H	698	Missense	distal	5	no	18.849	18.821	EPSD	ICGC;COSMIC	8.808	Down-regulation
CMGC_CDK_CDK5_CDK5_ST	P35612	ADD2	Q00535	CDK5	S697	P698H	698	Missense	proximal	1	no	19.283	0.771	EPSD	ICGC;COSMIC	8.808	Loss
CMGC_CDK_CDK5_CDK5_ST	P35612	ADD2	Q00535	CDK5	S697	G690D	690	Missense	distal	-7	no	19.283	19.291	EPSD	ICGC	8.808	Up-regulation
CMGC_CDK_CDK5_CDK5_ST	P35612	ADD2	Q00535	CDK5	S701	P698H	698	Missense	distal	-3	no	19.958	19.936	PhosphoSitePlus;EPSD	ICGC;COSMIC	8.808	Down-regulation
CMGC_CDK_CDK5_CDK5_ST	P35612	ADD2	Q00535	CDK5	T711	S718I	718	Missense	distal	7	no	17.101	17.095	EPSD	ICGC;CCLE	8.808	Down-regulation
CMGC_CDK_CDK5_CDK5_ST	O00429	DNM1L	Q00535	CDK5	S126	K123N	123	Missense	distal	-3	no	17.427	17.375	EPSD	ICGC;COSMIC	8.808	Down-regulation
CMGC_CDK_CDK5_CDK5_ST	O00429	DNM1L	Q00535	CDK5	S200	A196T	196	Missense	distal	-4	no	8.522	8.921	EPSD	ICGC;COSMIC	8.808	Gain
CMGC_CDK_CDK5_CDK5_ST	O00429	DNM1L	Q00535	CDK5	S529	R530I	530	Missense	proximal	1	no	11.576	3.437	EPSD	ICGC;COSMIC	8.808	Loss
CMGC_CDK_CDK5_CDK5_ST	O00429	DNM1L	Q00535	CDK5	S548	A541S	541	Missense	distal	-7	no	17.721	17.775	EPSD	ICGC	8.808	Up-regulation
CMGC_CDK_CDK5_CDK5_ST	O00429	DNM1L	Q00535	CDK5	S548	S548F	548	Missense	central	0	yes	17.721	0.000	EPSD	ICGC;COSMIC	8.808	Loss
CMGC_CDK_CDK5_CDK5_ST	O00429	DNM1L	Q00535	CDK5	S548	A553T	553	Missense	distal	5	no	17.721	17.855	EPSD	ICGC	8.808	Up-regulation
CMGC_CDK_CDK5_CDK5_ST	O00429	DNM1L	Q00535	CDK5	S548	A553V	553	Missense	distal	5	no	17.721	17.818	EPSD	ICGC;COSMIC	8.808	Up-regulation
CMGC_CDK_CDK5_CDK5_ST	O00429	DNM1L	Q00535	CDK5	S548	S548Y	548	Missense	central	0	yes	17.721	0.000	EPSD	ICGC;COSMIC	8.808	Loss
CMGC_CDK_CDK5_CDK5_ST	Q8IV63	VRK3	Q00535	CDK5	S59	S54T	54	Missense	distal	-5	no	20.284	20.258	EPSD	ICGC	8.808	Down-regulation
CMGC_CDK_CDK5_CDK5_ST	Q8IV63	VRK3	Q00535	CDK5	S59	S54F	54	Missense	distal	-5	no	20.284	19.954	EPSD	ICGC	8.808	Down-regulation
CMGC_CDK_CDK5_CDK5_ST	Q8IV63	VRK3	Q00535	CDK5	S71	R73Q	73	Missense	proximal	2	no	17.408	17.268	EPSD	ICGC;COSMIC	8.808	Down-regulation
CMGC_CDK_CDK5_CDK5_ST	Q8IV63	VRK3	Q00535	CDK5	S100	R94Q	94	Missense	distal	-6	no	9.393	9.336	EPSD	ICGC;COSMIC	8.808	Down-regulation
CMGC_CDK_CDK5_CDK5_ST	Q8IV63	VRK3	Q00535	CDK5	S100	R94L	94	Missense	distal	-6	no	9.393	9.264	EPSD	ICGC;COSMIC	8.808	Down-regulation
CMGC_CDK_CDK5_CDK5_ST	Q16665	HIF1A	Q00535	CDK5	S14	K10N	10	Missense	distal	-4	no	9.177	8.789	EPSD	ICGC;COSMIC	8.808	Loss
CMGC_CDK_CDK5_CDK5_ST	Q16665	HIF1A	Q00535	CDK5	S14	R18Q	18	Missense	distal	4	no	9.177	9.131	EPSD	ICGC;COSMIC	8.808	Down-regulation
CMGC_CDK_CDK5_CDK5_ST	Q16665	HIF1A	Q00535	CDK5	S14	R17G	17	Missense	distal	3	no	9.177	7.795	EPSD	ICGC;COSMIC	8.808	Loss
CMGC_CDK_CDK5_CDK5_ST	Q16665	HIF1A	Q00535	CDK5	S14	K19Q	19	Missense	distal	5	no	9.177	8.977	EPSD	ICGC;COSMIC	8.808	Down-regulation
CMGC_CDK_CDK5_CDK5_ST	Q15717	ELAVL1	Q00535	CDK5	S146	V139M	139	Missense	distal	-7	no	8.850	8.796	EPSD	ICGC;COSMIC	8.808	Loss
CMGC_CDK_CDK5_CDK5_ST	Q15717	ELAVL1	Q00535	CDK5	S146	A150V	150	Missense	distal	4	no	8.850	8.893	EPSD	ICGC;COSMIC	8.808	Up-regulation
CMGC_CDK_CDK5_CDK5_ST	Q15717	ELAVL1	Q00535	CDK5	S146	F151S	151	Missense	distal	5	no	8.850	9.090	EPSD	ICGC;COSMIC	8.808	Up-regulation
CMGC_CDK_CDK5_CDK5_ST	Q15717	ELAVL1	Q00535	CDK5	S146	G148V	148	Missense	proximal	2	no	8.850	8.911	EPSD	ICGC;COSMIC	8.808	Up-regulation
CMGC_CDK_CDK5_CDK5_ST	Q15717	ELAVL1	Q00535	CDK5	S221	A215V	215	Missense	distal	-6	no	17.779	17.849	EPSD	ICGC;COSMIC	8.808	Up-regulation
CMGC_CDK_CDK5_CDK5_ST	Q15717	ELAVL1	Q00535	CDK5	S221	S221F	221	Missense	central	0	yes	17.779	0.000	EPSD	ICGC;COSMIC	8.808	Loss
CMGC_CDK_CDK5_CDK5_ST	Q15717	ELAVL1	Q00535	CDK5	S221	G224C	224	Missense	distal	3	no	17.779	16.865	EPSD	ICGC	8.808	Down-regulation
CMGC_CDK_CDK5_CDK5_ST	Q15717	ELAVL1	Q00535	CDK5	S221	F218L	218	Missense	distal	-3	no	17.779	17.801	EPSD	ICGC	8.808	Up-regulation
CMGC_CDK_CDK5_CDK5_ST	Q15717	ELAVL1	Q00535	CDK5	S221	Q216R	216	Missense	distal	-5	no	17.779	17.940	EPSD	ICGC;COSMIC	8.808	Up-regulation
CMGC_CDK_CDK5_CDK5_ST	Q02750	MAP2K1	Q00535	CDK5	S231	P232R	232	Missense	proximal	1	no	19.243	10.296	EPSD	ICGC	8.808	Down-regulation
CMGC_CDK_CDK5_CDK5_ST	Q02750	MAP2K1	Q00535	CDK5	S231	R234I	234	Missense	distal	3	no	19.243	17.403	EPSD	ICGC	8.808	Down-regulation
CMGC_CDK_CDK5_CDK5_ST	Q02750	MAP2K1	Q00535	CDK5	S231	G225C	225	Missense	distal	-6	no	19.243	19.192	EPSD	ICGC	8.808	Down-regulation
CMGC_CDK_CDK5_CDK5_ST	Q02750	MAP2K1	Q00535	CDK5	T286	P288H	288	Missense	proximal	2	no	18.401	18.368	EPSD	ICGC;COSMIC	8.808	Down-regulation
CMGC_CDK_CDK5_CDK5_ST	Q02750	MAP2K1	Q00535	CDK5	T292	P288H	288	Missense	distal	-4	no	19.368	19.033	PhosphoSitePlus	ICGC;COSMIC	8.808	Down-regulation
CMGC_CDK_CDK5_CDK5_ST	Q02750	MAP2K1	Q00535	CDK5	T292	G294W	294	Missense	proximal	2	no	19.368	19.349	PhosphoSitePlus	ICGC;COSMIC	8.808	Down-regulation
CMGC_CDK_CDK5_CDK5_ST	Q02750	MAP2K1	Q00535	CDK5	T292	P296H	296	Missense	distal	4	no	19.368	19.347	PhosphoSitePlus	ICGC;COSMIC	8.808	Down-regulation
CMGC_CDK_CDK5_CDK5_ST	Q02750	MAP2K1	Q00535	CDK5	T386	S385G	385	Missense	proximal	-1	no	18.515	18.510	EPSD	ICGC	8.808	Down-regulation
CMGC_CDK_CDK5_CDK5_ST	Q14814	MEF2D	Q00535	CDK5	S78	N73I	73	Missense	distal	-5	no	8.836	8.795	EPSD	ICGC;COSMIC	8.808	Loss
CMGC_CDK_CDK5_CDK5_ST	Q14814	MEF2D	Q00535	CDK5	S78	T80S	80	Missense	proximal	2	no	8.836	8.811	EPSD	ICGC;COSMIC	8.808	Down-regulation
CMGC_CDK_CDK5_CDK5_ST	Q14814	MEF2D	Q00535	CDK5	S78	E71Q	71	Missense	distal	-7	no	8.836	8.861	EPSD	ICGC;COSMIC	8.808	Up-regulation
CMGC_CDK_CDK5_CDK5_ST	Q14814	MEF2D	Q00535	CDK5	S78	Y72C	72	Missense	distal	-6	no	8.836	8.823	EPSD	ICGC;COSMIC	8.808	Down-regulation
CMGC_CDK_CDK5_CDK5_ST	Q14814	MEF2D	Q00535	CDK5	S98	P101T	101	Missense	distal	3	no	16.728	17.264	EPSD	ICGC	8.808	Up-regulation
CMGC_CDK_CDK5_CDK5_ST	Q14814	MEF2D	Q00535	CDK5	S98	P101L	101	Missense	distal	3	no	16.728	15.656	EPSD	ICGC;GDSC;CCLE	8.808	Down-regulation
CMGC_CDK_CDK5_CDK5_ST	Q14814	MEF2D	Q00535	CDK5	S110	S110G	110	Missense	central	0	yes	16.893	0.000	EPSD	ICGC	8.808	Loss
CMGC_CDK_CDK5_CDK5_ST	Q96KR7	PHACTR3	Q00535	CDK5	S156	S149C	149	Missense	distal	-7	no	17.190	17.118	EPSD	ICGC;COSMIC	8.808	Down-regulation
CMGC_CDK_CDK5_CDK5_ST	Q96KR7	PHACTR3	Q00535	CDK5	S156	E150K	150	Missense	distal	-6	no	17.190	17.320	EPSD	ICGC;COSMIC	8.808	Up-regulation
CMGC_CDK_CDK5_CDK5_ST	P01106	MYC	Q00535	CDK5	T8	N9K	9	Missense	proximal	1	no	8.962	0.023	EPSD	ICGC;COSMIC	8.808	Loss
CMGC_CDK_CDK5_CDK5_ST	P01106	MYC	Q00535	CDK5	S71	P72S	72	Missense	proximal	1	no	17.722	5.821	EPSD	ICGC;COSMIC;GDSC	8.808	Loss
CMGC_CDK_CDK5_CDK5_ST	P01106	MYC	Q00535	CDK5	S71	P72A	72	Missense	proximal	1	no	17.722	6.695	EPSD	ICGC;COSMIC	8.808	Loss
CMGC_CDK_CDK5_CDK5_ST	P01106	MYC	Q00535	CDK5	S71	P72L	72	Missense	proximal	1	no	17.722	5.772	EPSD	ICGC;COSMIC	8.808	Loss
CMGC_CDK_CDK5_CDK5_ST	P01106	MYC	Q00535	CDK5	S71	P72T	72	Missense	proximal	1	no	17.722	7.234	EPSD	ICGC;COSMIC;GDSC	8.808	Loss
CMGC_CDK_CDK5_CDK5_ST	P01106	MYC	Q00535	CDK5	T78	P72S	72	Missense	distal	-6	no	16.878	16.917	EPSD	ICGC;COSMIC;GDSC	8.808	Up-regulation
CMGC_CDK_CDK5_CDK5_ST	P01106	MYC	Q00535	CDK5	T78	P72A	72	Missense	distal	-6	no	16.878	16.803	EPSD	ICGC;COSMIC	8.808	Down-regulation
CMGC_CDK_CDK5_CDK5_ST	P01106	MYC	Q00535	CDK5	T78	P72L	72	Missense	distal	-6	no	16.878	16.795	EPSD	ICGC;COSMIC	8.808	Down-regulation
CMGC_CDK_CDK5_CDK5_ST	P01106	MYC	Q00535	CDK5	T78	P72T	72	Missense	distal	-6	no	16.878	16.889	EPSD	ICGC;COSMIC;GDSC	8.808	Up-regulation
CMGC_CDK_CDK5_CDK5_ST	Q14195	DPYSL3	Q00535	CDK5	S265	A260E	260	Missense	distal	-5	no	10.617	10.624	EPSD	ICGC;COSMIC	8.808	Up-regulation
CMGC_CDK_CDK5_CDK5_ST	Q14195	DPYSL3	Q00535	CDK5	S265	K270N	270	Missense	distal	5	no	10.617	10.415	EPSD	ICGC;COSMIC	8.808	Down-regulation
CMGC_CDK_CDK5_CDK5_ST	Q14195	DPYSL3	Q00535	CDK5	S265	K270E	270	Missense	distal	5	no	10.617	10.366	EPSD	ICGC;COSMIC	8.808	Down-regulation
CMGC_CDK_CDK5_CDK5_ST	Q14195	DPYSL3	Q00535	CDK5	S304	A298V	298	Missense	distal	-6	no	17.160	17.230	EPSD	ICGC;COSMIC	8.808	Up-regulation
CMGC_CDK_CDK5_CDK5_ST	Q14195	DPYSL3	Q00535	CDK5	S304	V302L	302	Missense	proximal	-2	no	17.160	16.927	EPSD	ICGC;COSMIC	8.808	Down-regulation
CMGC_CDK_CDK5_CDK5_ST	Q14195	DPYSL3	Q00535	CDK5	S304	P306L	306	Missense	proximal	2	no	17.160	16.995	EPSD	ICGC	8.808	Down-regulation
CMGC_CDK_CDK5_CDK5_ST	Q14195	DPYSL3	Q00535	CDK5	S304	A300T	300	Missense	distal	-4	no	17.160	17.560	EPSD	ICGC;COSMIC	8.808	Up-regulation
CMGC_CDK_CDK5_CDK5_ST	Q14195	DPYSL3	Q00535	CDK5	S304	V302A	302	Missense	proximal	-2	no	17.160	16.964	EPSD	ICGC	8.808	Down-regulation
CMGC_CDK_CDK5_CDK5_ST	Q14195	DPYSL3	Q00535	CDK5	S308	P314Q	314	Missense	distal	6	no	18.614	18.611	EPSD	ICGC	8.808	Down-regulation
CMGC_CDK_CDK5_CDK5_ST	Q14195	DPYSL3	Q00535	CDK5	S308	V302L	302	Missense	distal	-6	no	18.614	18.537	EPSD	ICGC;COSMIC	8.808	Down-regulation
CMGC_CDK_CDK5_CDK5_ST	Q14195	DPYSL3	Q00535	CDK5	S308	P306L	306	Missense	proximal	-2	no	18.614	18.200	EPSD	ICGC	8.808	Down-regulation
CMGC_CDK_CDK5_CDK5_ST	Q14195	DPYSL3	Q00535	CDK5	S308	V302A	302	Missense	distal	-6	no	18.614	18.545	EPSD	ICGC	8.808	Down-regulation
CMGC_CDK_CDK5_CDK5_ST	Q14195	DPYSL3	Q00535	CDK5	S472	R467L	467	Missense	distal	-5	no	17.452	17.152	EPSD	ICGC;COSMIC	8.808	Down-regulation
CMGC_CDK_CDK5_CDK5_ST	Q14195	DPYSL3	Q00535	CDK5	S472	R467H	467	Missense	distal	-5	no	17.452	17.280	EPSD	ICGC;COSMIC;GDSC;CCLE	8.808	Down-regulation
CMGC_CDK_CDK5_CDK5_ST	Q14195	DPYSL3	Q00535	CDK5	T509	A516E	516	Missense	distal	7	no	17.034	17.035	EPSD	ICGC;COSMIC	8.808	Up-regulation
CMGC_CDK_CDK5_CDK5_ST	Q14195	DPYSL3	Q00535	CDK5	T509	T509N	509	Missense	central	0	yes	17.034	0.000	EPSD	ICGC;COSMIC	8.808	Loss
CMGC_CDK_CDK5_CDK5_ST	Q14195	DPYSL3	Q00535	CDK5	T509	P502L	502	Missense	distal	-7	no	17.034	16.982	EPSD	ICGC;COSMIC	8.808	Down-regulation
CMGC_CDK_CDK5_CDK5_ST	Q14195	DPYSL3	Q00535	CDK5	T509	T507I	507	Missense	proximal	-2	no	17.034	16.852	EPSD	ICGC;COSMIC	8.808	Down-regulation
CMGC_CDK_CDK5_CDK5_ST	Q14195	DPYSL3	Q00535	CDK5	T514	R520W	520	Missense	distal	6	no	17.300	17.283	EPSD	ICGC;COSMIC	8.808	Down-regulation
CMGC_CDK_CDK5_CDK5_ST	Q14195	DPYSL3	Q00535	CDK5	T514	A516E	516	Missense	proximal	2	no	17.300	17.292	EPSD	ICGC;COSMIC	8.808	Down-regulation
CMGC_CDK_CDK5_CDK5_ST	Q14195	DPYSL3	Q00535	CDK5	T514	T509N	509	Missense	distal	-5	no	17.300	17.234	EPSD	ICGC;COSMIC	8.808	Down-regulation
CMGC_CDK_CDK5_CDK5_ST	Q14195	DPYSL3	Q00535	CDK5	T514	T507I	507	Missense	distal	-7	no	17.300	17.281	EPSD	ICGC;COSMIC	8.808	Down-regulation
CMGC_CDK_CDK5_CDK5_ST	Q14195	DPYSL3	Q00535	CDK5	S522	R520W	520	Missense	proximal	-2	no	20.102	19.729	PhosphoSitePlus	ICGC;COSMIC	8.808	Down-regulation
CMGC_CDK_CDK5_CDK5_ST	Q14195	DPYSL3	Q00535	CDK5	S522	P526L	526	Missense	distal	4	no	20.102	20.020	PhosphoSitePlus	ICGC;COSMIC	8.808	Down-regulation
CMGC_CDK_CDK5_CDK5_ST	Q14195	DPYSL3	Q00535	CDK5	S522	A516E	516	Missense	distal	-6	no	20.102	20.129	PhosphoSitePlus	ICGC;COSMIC	8.808	Up-regulation
CMGC_CDK_CDK5_CDK5_ST	Q14195	DPYSL3	Q00535	CDK5	S522	P528T	528	Missense	distal	6	no	20.102	20.103	PhosphoSitePlus	ICGC	8.808	Up-regulation
CMGC_CDK_CDK5_CDK5_ST	Q14195	DPYSL3	Q00535	CDK5	S522	S522F	522	Missense	central	0	yes	20.102	0.000	PhosphoSitePlus	ICGC	8.808	Loss
CMGC_CDK_CDK5_CDK5_ST	Q14195	DPYSL3	Q00535	CDK5	S564	R563H	563	Missense	proximal	-1	no	9.910	9.908	EPSD	ICGC	8.808	Down-regulation
CMGC_CDK_CDK5_CDK5_ST	Q14195	DPYSL3	Q00535	CDK5	S564	R563L	563	Missense	proximal	-1	no	9.910	9.905	EPSD	ICGC;COSMIC	8.808	Down-regulation
CMGC_CDK_CDK5_CDK5_ST	Q14195	DPYSL3	Q00535	CDK5	S564	G562S	562	Missense	proximal	-2	no	9.910	10.276	EPSD	ICGC;COSMIC	8.808	Up-regulation
CMGC_CDK_CDK5_CDK5_ST	Q14195	DPYSL3	Q00535	CDK5	S564	I566M	566	Missense	proximal	2	no	9.910	9.807	EPSD	ICGC;COSMIC	8.808	Down-regulation
CMGC_CDK_CDK5_CDK5_ST	Q14195	DPYSL3	Q00535	CDK5	S564	A558V	558	Missense	distal	-6	no	9.910	9.980	EPSD	ICGC;COSMIC	8.808	Up-regulation
CMGC_CDK_CDK5_CDK5_ST	P09874	PARP1	Q00535	CDK5	S179	S177N	177	Missense	proximal	-2	no	10.289	10.175	EPSD	ICGC;COSMIC	8.808	Down-regulation
CMGC_CDK_CDK5_CDK5_ST	P09874	PARP1	Q00535	CDK5	S179	Q180H	180	Missense	proximal	1	no	10.289	0.753	EPSD	ICGC;COSMIC	8.808	Loss
CMGC_CDK_CDK5_CDK5_ST	P09874	PARP1	Q00535	CDK5	T327	W333L	333	Missense	distal	6	no	18.538	18.533	EPSD	ICGC;COSMIC	8.808	Down-regulation
CMGC_CDK_CDK5_CDK5_ST	P09874	PARP1	Q00535	CDK5	T335	E341Q	341	Missense	distal	6	no	17.237	17.243	EPSD	ICGC	8.808	Up-regulation
CMGC_CDK_CDK5_CDK5_ST	P09874	PARP1	Q00535	CDK5	T335	R340Q	340	Missense	distal	5	no	17.237	17.112	EPSD	ICGC;COSMIC	8.808	Down-regulation
CMGC_CDK_CDK5_CDK5_ST	P09874	PARP1	Q00535	CDK5	T335	W333L	333	Missense	proximal	-2	no	17.237	17.250	EPSD	ICGC;COSMIC	8.808	Up-regulation
CMGC_CDK_CDK5_CDK5_ST	P09874	PARP1	Q00535	CDK5	T368	T368K	368	Missense	central	0	yes	17.579	0.000	EPSD	ICGC	8.808	Loss
CMGC_CDK_CDK5_CDK5_ST	P09874	PARP1	Q00535	CDK5	S391	P389T	389	Missense	proximal	-2	no	10.337	10.197	EPSD	ICGC	8.808	Down-regulation
CMGC_CDK_CDK5_CDK5_ST	P09874	PARP1	Q00535	CDK5	S431	I430V	430	Missense	proximal	-1	no	9.235	9.236	EPSD	ICGC	8.808	Up-regulation
CMGC_CDK_CDK5_CDK5_ST	P09874	PARP1	Q00535	CDK5	S431	K434E	434	Missense	distal	3	no	9.235	6.948	EPSD	ICGC	8.808	Loss
CMGC_CDK_CDK5_CDK5_ST	P09874	PARP1	Q00535	CDK5	S431	A426S	426	Missense	distal	-5	no	9.235	9.416	EPSD	ICGC;COSMIC	8.808	Up-regulation
CMGC_CDK_CDK5_CDK5_ST	P09874	PARP1	Q00535	CDK5	S479	V485L	485	Missense	distal	6	no	17.232	17.221	EPSD	ICGC	8.808	Down-regulation
CMGC_CDK_CDK5_CDK5_ST	P09874	PARP1	Q00535	CDK5	S479	A475T	475	Missense	distal	-4	no	17.232	17.632	EPSD	ICGC;COSMIC	8.808	Up-regulation
CMGC_CDK_CDK5_CDK5_ST	P09874	PARP1	Q00535	CDK5	S721	E715Q	715	Missense	distal	-6	no	8.778	8.814	EPSD	ICGC;COSMIC	8.808	Gain
CMGC_CDK_CDK5_CDK5_ST	P09874	PARP1	Q00535	CDK5	S724	S725R	725	Missense	proximal	1	no	6.073	9.027	EPSD	ICGC;COSMIC	8.808	Gain
CMGC_CDK_CDK5_CDK5_ST	Q16555	DPYSL2	Q00535	CDK5	S304	D310G	310	Missense	distal	6	no	16.977	16.978	EPSD	ICGC;COSMIC	8.808	Up-regulation
CMGC_CDK_CDK5_CDK5_ST	Q16555	DPYSL2	Q00535	CDK5	S308	D310G	310	Missense	proximal	2	no	18.358	18.390	EPSD	ICGC;COSMIC	8.808	Up-regulation
CMGC_CDK_CDK5_CDK5_ST	Q16555	DPYSL2	Q00535	CDK5	T509	P515L	515	Missense	distal	6	no	17.252	17.238	EPSD	ICGC	8.808	Down-regulation
CMGC_CDK_CDK5_CDK5_ST	Q16555	DPYSL2	Q00535	CDK5	T514	P515L	515	Missense	proximal	1	no	17.700	5.750	EPSD	ICGC	8.808	Loss
CMGC_CDK_CDK5_CDK5_ST	Q16555	DPYSL2	Q00535	CDK5	S522	P515L	515	Missense	distal	-7	no	20.593	20.541	PhosphoSitePlus	ICGC	8.808	Down-regulation
CMGC_CDK_CDK5_CDK5_ST	P27695	APEX1	Q00535	CDK5	S54	P48H	48	Missense	distal	-6	no	17.662	17.642	EPSD	ICGC;COSMIC	8.808	Down-regulation
CMGC_CDK_CDK5_CDK5_ST	P27695	APEX1	Q00535	CDK5	S54	K58N	58	Missense	distal	4	no	17.662	17.567	EPSD	ICGC;COSMIC	8.808	Down-regulation
CMGC_CDK_CDK5_CDK5_ST	P27695	APEX1	Q00535	CDK5	T233	F240V	240	Missense	distal	7	no	17.263	17.277	PhosphoSitePlus	ICGC	8.808	Up-regulation
CMGC_CDK_CDK5_CDK5_ST	P27695	APEX1	Q00535	CDK5	T233	K228Q	228	Missense	distal	-5	no	17.263	17.067	PhosphoSitePlus	ICGC	8.808	Down-regulation
CMGC_CDK_CDK5_CDK5_ST	P27695	APEX1	Q00535	CDK5	T260	F266Y	266	Missense	distal	6	no	17.060	17.066	EPSD	ICGC;COSMIC	8.808	Up-regulation
CMGC_CDK_CDK5_CDK5_ST	P27695	APEX1	Q00535	CDK5	T260	F266L	266	Missense	distal	6	no	17.060	17.066	EPSD	ICGC;COSMIC	8.808	Up-regulation
CMGC_CDK_CDK5_CDK5_ST	P06400	RB1	Q00535	CDK5	T5	A10S	10	Missense	distal	5	no	19.240	19.375	EPSD	ICGC	8.808	Up-regulation
CMGC_CDK_CDK5_CDK5_ST	P06400	RB1	Q00535	CDK5	T5	A11T	11	Missense	distal	6	no	19.240	19.253	EPSD	ICGC;COSMIC	8.808	Up-regulation
CMGC_CDK_CDK5_CDK5_ST	P06400	RB1	Q00535	CDK5	S230	D224E	224	Missense	distal	-6	no	15.282	15.292	EPSD	ICGC;COSMIC	8.808	Up-regulation
CMGC_CDK_CDK5_CDK5_ST	P06400	RB1	Q00535	CDK5	S249	R251L	251	Missense	proximal	2	no	19.717	19.470	EPSD	ICGC	8.808	Down-regulation
CMGC_CDK_CDK5_CDK5_ST	P06400	RB1	Q00535	CDK5	S249	G256C	256	Missense	distal	7	no	19.717	19.712	EPSD	ICGC	8.808	Down-regulation
CMGC_CDK_CDK5_CDK5_ST	P06400	RB1	Q00535	CDK5	T252	R251L	251	Missense	proximal	-1	no	18.798	18.792	EPSD	ICGC	8.808	Down-regulation
CMGC_CDK_CDK5_CDK5_ST	P06400	RB1	Q00535	CDK5	T252	G256C	256	Missense	distal	4	no	18.798	18.757	EPSD	ICGC	8.808	Down-regulation
CMGC_CDK_CDK5_CDK5_ST	P06400	RB1	Q00535	CDK5	T356	Q354H	354	Missense	proximal	-2	no	18.896	18.771	EPSD	ICGC;COSMIC	8.808	Down-regulation
CMGC_CDK_CDK5_CDK5_ST	P06400	RB1	Q00535	CDK5	S567	L572I	572	Missense	distal	5	no	16.330	16.425	EPSD	ICGC;COSMIC	8.808	Up-regulation
CMGC_CDK_CDK5_CDK5_ST	P06400	RB1	Q00535	CDK5	S567	D571Y	571	Missense	distal	4	no	16.330	16.305	EPSD	ICGC	8.808	Down-regulation
CMGC_CDK_CDK5_CDK5_ST	P06400	RB1	Q00535	CDK5	S567	W563L	563	Missense	distal	-4	no	16.330	16.320	EPSD	ICGC	8.808	Down-regulation
CMGC_CDK_CDK5_CDK5_ST	P06400	RB1	Q00535	CDK5	S567	A562P	562	Missense	distal	-5	no	16.330	16.489	EPSD	ICGC;COSMIC;GDSC;CCLE	8.808	Up-regulation
CMGC_CDK_CDK5_CDK5_ST	P06400	RB1	Q00535	CDK5	S567	L564F	564	Missense	distal	-3	no	16.330	16.308	EPSD	ICGC	8.808	Down-regulation
CMGC_CDK_CDK5_CDK5_ST	P06400	RB1	Q00535	CDK5	S780	P783L	783	Missense	distal	3	no	18.526	17.455	EPSD	ICGC	8.808	Down-regulation
CMGC_CDK_CDK5_CDK5_ST	P06400	RB1	Q00535	CDK5	S788	P783L	783	Missense	distal	-5	no	19.412	19.215	EPSD	ICGC	8.808	Down-regulation
CMGC_CDK_CDK5_CDK5_ST	P06400	RB1	Q00535	CDK5	S795	L797S	797	Missense	proximal	2	no	19.344	19.492	PhosphoSitePlus;EPSD	ICGC;COSMIC	8.808	Up-regulation
CMGC_CDK_CDK5_CDK5_ST	P06400	RB1	Q00535	CDK5	S807	G801E	801	Missense	distal	-6	no	19.364	19.372	EPSD;PhosphoSitePlus	ICGC	8.808	Up-regulation
CMGC_CDK_CDK5_CDK5_ST	P06400	RB1	Q00535	CDK5	S866	K873E	873	Missense	distal	7	no	9.352	9.336	EPSD	ICGC;COSMIC	8.808	Down-regulation
CMGC_CDK_CDK5_CDK5_ST	P06400	RB1	Q00535	CDK5	S866	P871Q	871	Missense	distal	5	no	9.352	9.302	EPSD	ICGC;COSMIC	8.808	Down-regulation
CMGC_CDK_CDK5_CDK5_ST	Q16236	NFE2L2	Q00535	CDK5	S215	M212I	212	Missense	distal	-3	no	17.627	17.668	EPSD	ICGC;COSMIC	8.808	Up-regulation
CMGC_CDK_CDK5_CDK5_ST	Q16236	NFE2L2	Q00535	CDK5	S351	L348I	348	Missense	distal	-3	no	18.757	18.788	EPSD	ICGC	8.808	Up-regulation
CMGC_CDK_CDK5_CDK5_ST	P35968	KDR	Q00535	CDK5	S229	E235K	235	Missense	distal	6	no	18.514	18.533	PhosphoSitePlus	ICGC;COSMIC	8.808	Up-regulation
CMGC_CDK_CDK5_CDK5_ST	P35968	KDR	Q00535	CDK5	S229	L236I	236	Missense	distal	7	no	18.514	18.520	PhosphoSitePlus	ICGC;COSMIC	8.808	Up-regulation
CMGC_CDK_CDK5_CDK5_ST	P35968	KDR	Q00535	CDK5	S229	H232Q	232	Missense	distal	3	no	18.514	17.731	PhosphoSitePlus	ICGC;COSMIC	8.808	Down-regulation
CMGC_CDK_CDK5_CDK5_ST	P35968	KDR	Q00535	CDK5	S229	L228P	228	Missense	proximal	-1	no	18.514	18.519	PhosphoSitePlus	ICGC;COSMIC	8.808	Up-regulation
CMGC_CDK_CDK5_CDK5_ST	P35968	KDR	Q00535	CDK5	S229	S229N	229	Missense	central	0	yes	18.514	0.000	PhosphoSitePlus	ICGC;COSMIC	8.808	Loss
CMGC_CDK_CDK5_CDK5_ST	P35968	KDR	Q00535	CDK5	S1231	Q1225K	1225	Missense	distal	-6	no	10.206	10.300	EPSD	ICGC;COSMIC	8.808	Up-regulation
CMGC_CDK_CDK5_CDK5_ST	P35968	KDR	Q00535	CDK5	S1231	L1224M	1224	Missense	distal	-7	no	10.206	10.190	EPSD	ICGC	8.808	Down-regulation
CMGC_CDK_CDK5_CDK5_ST	P35968	KDR	Q00535	CDK5	S1231	K1230N	1230	Missense	proximal	-1	no	10.206	10.202	EPSD	ICGC;COSMIC	8.808	Down-regulation
CMGC_CDK_CDK5_CDK5_ST	P35968	KDR	Q00535	CDK5	S1279	P1280L	1280	Missense	proximal	1	no	16.619	4.669	EPSD	ICGC;COSMIC	8.808	Loss
CMGC_CDK_CDK5_CDK5_ST	P35968	KDR	Q00535	CDK5	S1279	D1274E	1274	Missense	distal	-5	no	16.619	16.609	EPSD	ICGC	8.808	Down-regulation
CMGC_CDK_CDK5_CDK5_ST	P35222	CTNNB1	Q00535	CDK5	S246	L252H	252	Missense	distal	6	no	17.989	18.000	PhosphoSitePlus;EPSD	ICGC;COSMIC	8.808	Up-regulation
CMGC_CDK_CDK5_CDK5_ST	P35222	CTNNB1	Q00535	CDK5	T289	I296M	296	Missense	distal	7	no	9.190	9.182	EPSD	ICGC;COSMIC	8.808	Down-regulation
CMGC_CDK_CDK5_CDK5_ST	P35222	CTNNB1	Q00535	CDK5	T289	L294H	294	Missense	distal	5	no	9.190	9.334	EPSD	ICGC;COSMIC	8.808	Up-regulation
CMGC_CDK_CDK5_CDK5_ST	P35222	CTNNB1	Q00535	CDK5	T547	R542C	542	Missense	distal	-5	no	10.356	10.002	EPSD	ICGC;COSMIC	8.808	Down-regulation
CMGC_CDK_CDK5_CDK5_ST	Q9UKV5	AMFR	Q00535	CDK5	S516	P517H	517	Missense	proximal	1	no	17.792	-0.720	PhosphoSitePlus	ICGC	8.808	Loss
CMGC_CDK_CDK5_CDK5_ST	Q9UKV5	AMFR	Q00535	CDK5	S516	P517T	517	Missense	proximal	1	no	17.792	7.305	PhosphoSitePlus	ICGC;COSMIC	8.808	Loss
CMGC_CDK_CDK5_CDK5_ST	Q9UKV5	AMFR	Q00535	CDK5	S516	I510F	510	Missense	distal	-6	no	17.792	17.691	PhosphoSitePlus	ICGC;COSMIC	8.808	Down-regulation
CMGC_CDK_CDK5_CDK5_ST	Q9UKV5	AMFR	Q00535	CDK5	S542	T548M	548	Missense	distal	6	no	17.031	17.014	EPSD	ICGC;COSMIC	8.808	Down-regulation
CMGC_CDK_CDK5_CDK5_ST	Q9UKV5	AMFR	Q00535	CDK5	S542	P538Q	538	Missense	distal	-4	no	17.031	16.906	EPSD	ICGC	8.808	Down-regulation
CMGC_CDK_CDK5_CDK5_ST	Q9UKV5	AMFR	Q00535	CDK5	T623	L624P	624	Missense	proximal	1	no	7.773	19.723	EPSD	ICGC;COSMIC	8.808	Gain
CMGC_CDK_CDK5_CDK5_ST	P40763	STAT3	Q00535	CDK5	T714	T717N	717	Missense	distal	3	no	17.499	16.748	EPSD	ICGC	8.808	Down-regulation
CMGC_CDK_CDK5_CDK5_ST	P40763	STAT3	Q00535	CDK5	T714	P715L	715	Missense	proximal	1	no	17.499	5.549	EPSD	ICGC	8.808	Loss
CMGC_CDK_CDK5_CDK5_ST	P40763	STAT3	Q00535	CDK5	T714	P715Q	715	Missense	proximal	1	no	17.499	8.523	EPSD	ICGC;COSMIC	8.808	Loss
CMGC_CDK_CDK5_CDK5_ST	P40763	STAT3	Q00535	CDK5	S727	L724P	724	Missense	distal	-3	no	19.471	19.532	PhosphoSitePlus	ICGC;COSMIC	8.808	Up-regulation
CMGC_CDK_CDK5_CDK5_ST	P40763	STAT3	Q00535	CDK5	S727	S727P	727	Missense	central	0	yes	19.471	0.000	PhosphoSitePlus	ICGC	8.808	Loss
CMGC_CDK_CDK5_CDK5_ST	P40763	STAT3	Q00535	CDK5	S727	L734S	734	Missense	distal	7	no	19.471	19.483	PhosphoSitePlus	ICGC;COSMIC	8.808	Up-regulation
CMGC_CDK_CDK5_CDK5_ST	Q05193	DNM1	Q00535	CDK5	S116	T111S	111	Missense	distal	-5	no	17.961	17.987	EPSD	ICGC;COSMIC;GDSC	8.808	Up-regulation
CMGC_CDK_CDK5_CDK5_ST	Q05193	DNM1	Q00535	CDK5	S116	V118L	118	Missense	proximal	2	no	17.961	17.827	EPSD	ICGC;COSMIC	8.808	Down-regulation
CMGC_CDK_CDK5_CDK5_ST	Q05193	DNM1	Q00535	CDK5	S116	G114V	114	Missense	proximal	-2	no	17.961	18.244	EPSD	ICGC	8.808	Up-regulation
CMGC_CDK_CDK5_CDK5_ST	Q05193	DNM1	Q00535	CDK5	S126	H128R	128	Missense	proximal	2	no	18.047	18.162	EPSD	ICGC;COSMIC	8.808	Up-regulation
CMGC_CDK_CDK5_CDK5_ST	Q05193	DNM1	Q00535	CDK5	S126	P127Q	127	Missense	proximal	1	no	18.047	9.071	EPSD	ICGC;COSMIC	8.808	Down-regulation
CMGC_CDK_CDK5_CDK5_ST	Q05193	DNM1	Q00535	CDK5	T404	G401W	401	Missense	distal	-3	no	16.122	16.124	EPSD	ICGC;COSMIC	8.808	Up-regulation
CMGC_CDK_CDK5_CDK5_ST	Q05193	DNM1	Q00535	CDK5	S774	A770T	770	Missense	distal	-4	no	17.473	17.873	EPSD	ICGC;COSMIC	8.808	Up-regulation
CMGC_CDK_CDK5_CDK5_ST	Q05193	DNM1	Q00535	CDK5	S774	A770D	770	Missense	distal	-4	no	17.473	17.699	EPSD	ICGC	8.808	Up-regulation
CMGC_CDK_CDK5_CDK5_ST	Q05193	DNM1	Q00535	CDK5	S774	G771E	771	Missense	distal	-3	no	17.473	17.476	EPSD	ICGC	8.808	Up-regulation
CMGC_CDK_CDK5_CDK5_ST	Q05193	DNM1	Q00535	CDK5	S778	G771E	771	Missense	distal	-7	no	18.092	18.098	EPSD	ICGC	8.808	Up-regulation
CMGC_CDK_CDK5_CDK5_ST	Q05193	DNM1	Q00535	CDK5	S822	G827S	827	Missense	distal	5	no	17.194	17.298	EPSD	ICGC	8.808	Up-regulation
CMGC_CDK_CDK5_CDK5_ST	Q05193	DNM1	Q00535	CDK5	S822	V815M	815	Missense	distal	-7	no	17.194	17.140	EPSD	ICGC	8.808	Down-regulation
CMGC_CDK_CDK5_CDK5_ST	Q05193	DNM1	Q00535	CDK5	S822	S822P	822	Missense	central	0	yes	17.194	0.000	EPSD	ICGC;COSMIC	8.808	Loss
CMGC_CDK_CDK5_CDK5_ST	Q05193	DNM1	Q00535	CDK5	S834	G827S	827	Missense	distal	-7	no	9.105	9.157	EPSD	ICGC	8.808	Up-regulation
CMGC_CDK_CDK5_CDK5_ST	Q05193	DNM1	Q00535	CDK5	S851	S847L	847	Missense	distal	-4	no	20.799	19.979	EPSD	ICGC;COSMIC	8.808	Down-regulation
CMGC_CDK_CDK5_CDK5_ST	Q05193	DNM1	Q00535	CDK5	S851	E856Q	856	Missense	distal	5	no	20.799	20.850	EPSD	ICGC;COSMIC	8.808	Up-regulation
CMGC_CDK_CDK5_CDK5_ST	Q05193	DNM1	Q00535	CDK5	S851	G848C	848	Missense	distal	-3	no	20.799	20.776	EPSD	ICGC	8.808	Down-regulation
CMGC_CDK_CDK5_CDK5_ST	Q05193	DNM1	Q00535	CDK5	S851	R854S	854	Missense	distal	3	no	20.799	19.380	EPSD	ICGC;COSMIC	8.808	Down-regulation
CMGC_CDK_CDK5_CDK5_ST	Q05193	DNM1	Q00535	CDK5	S853	S847L	847	Missense	distal	-6	no	8.972	8.850	EPSD	ICGC;COSMIC	8.808	Down-regulation
CMGC_CDK_CDK5_CDK5_ST	Q05193	DNM1	Q00535	CDK5	S853	E856Q	856	Missense	distal	3	no	8.972	9.136	EPSD	ICGC;COSMIC	8.808	Up-regulation
CMGC_CDK_CDK5_CDK5_ST	Q05193	DNM1	Q00535	CDK5	S853	G848C	848	Missense	distal	-5	no	8.972	8.870	EPSD	ICGC	8.808	Down-regulation
CMGC_CDK_CDK5_CDK5_ST	Q05193	DNM1	Q00535	CDK5	S853	R854S	854	Missense	proximal	1	no	8.972	6.018	EPSD	ICGC;COSMIC	8.808	Loss
CMGC_CDK_CDK5_CDK5_ST	Q05193	DNM1	Q00535	CDK5	S857	E856Q	856	Missense	proximal	-1	no	19.199	19.200	EPSD	ICGC;COSMIC	8.808	Up-regulation
CMGC_CDK_CDK5_CDK5_ST	Q05193	DNM1	Q00535	CDK5	S857	P861H	861	Missense	distal	4	no	19.199	19.178	EPSD	ICGC;COSMIC	8.808	Down-regulation
CMGC_CDK_CDK5_CDK5_ST	Q05193	DNM1	Q00535	CDK5	S857	R854S	854	Missense	distal	-3	no	19.199	19.184	EPSD	ICGC;COSMIC	8.808	Down-regulation
CMGC_CDK_CDK5_CDK5_ST	Q05193	DNM1	Q00535	CDK5	S857	D863N	863	Missense	distal	6	no	19.199	19.204	EPSD	ICGC;COSMIC	8.808	Up-regulation
CMGC_CDK_CDK5_CDK5_ST	Q96C19	EFHD2	Q00535	CDK5	S11	E5D	5	Missense	distal	-6	no	8.894	8.884	EPSD	ICGC;COSMIC	8.808	Down-regulation
CMGC_CDK_CDK5_CDK5_ST	Q96C19	EFHD2	Q00535	CDK5	S11	R12Q	12	Missense	proximal	1	no	8.894	8.865	EPSD	ICGC;COSMIC	8.808	Down-regulation
CMGC_CDK_CDK5_CDK5_ST	Q02078	MEF2A	Q00535	CDK5	S98	Y105C	105	Missense	distal	7	no	16.877	16.876	EPSD	ICGC;COSMIC	8.808	Down-regulation
CMGC_CDK_CDK5_CDK5_ST	Q02078	MEF2A	Q00535	CDK5	S98	P99S	99	Missense	proximal	1	no	16.877	4.976	EPSD	ICGC;COSMIC	8.808	Loss
CMGC_CDK_CDK5_CDK5_ST	Q02078	MEF2A	Q00535	CDK5	S98	D102E	102	Missense	distal	4	no	16.877	16.885	EPSD	ICGC;COSMIC	8.808	Up-regulation
CMGC_CDK_CDK5_CDK5_ST	Q02078	MEF2A	Q00535	CDK5	S98	D97N	97	Missense	proximal	-1	no	16.877	16.879	EPSD	ICGC	8.808	Up-regulation
CMGC_CDK_CDK5_CDK5_ST	Q02078	MEF2A	Q00535	CDK5	T108	H110Y	110	Missense	proximal	2	no	17.738	17.603	EPSD	ICGC;COSMIC	8.808	Down-regulation
CMGC_CDK_CDK5_CDK5_ST	Q02078	MEF2A	Q00535	CDK5	T108	Y105C	105	Missense	distal	-3	no	17.738	17.732	EPSD	ICGC;COSMIC	8.808	Down-regulation
CMGC_CDK_CDK5_CDK5_ST	Q02078	MEF2A	Q00535	CDK5	T108	V106L	106	Missense	proximal	-2	no	17.738	17.504	EPSD	ICGC	8.808	Down-regulation
CMGC_CDK_CDK5_CDK5_ST	Q02078	MEF2A	Q00535	CDK5	T108	E112D	112	Missense	distal	4	no	17.738	17.730	EPSD	ICGC	8.808	Down-regulation
CMGC_CDK_CDK5_CDK5_ST	Q02078	MEF2A	Q00535	CDK5	T108	D102E	102	Missense	distal	-6	no	17.738	17.748	EPSD	ICGC;COSMIC	8.808	Up-regulation
CMGC_CDK_CDK5_CDK5_ST	Q02078	MEF2A	Q00535	CDK5	S181	D176Y	176	Missense	distal	-5	no	17.456	17.372	EPSD	ICGC	8.808	Down-regulation
CMGC_CDK_CDK5_CDK5_ST	Q02078	MEF2A	Q00535	CDK5	S192	P196F	196	Missense	distal	4	no	17.180	17.070	EPSD	ICGC	8.808	Down-regulation
CMGC_CDK_CDK5_CDK5_ST	Q02078	MEF2A	Q00535	CDK5	S192	P196L	196	Missense	distal	4	no	17.180	17.099	EPSD	ICGC	8.808	Down-regulation
CMGC_CDK_CDK5_CDK5_ST	Q02078	MEF2A	Q00535	CDK5	S223	G226E	226	Missense	distal	3	no	17.690	17.105	EPSD	ICGC;COSMIC	8.808	Down-regulation
CMGC_CDK_CDK5_CDK5_ST	Q02078	MEF2A	Q00535	CDK5	S223	A220S	220	Missense	distal	-3	no	17.690	17.737	EPSD	ICGC;COSMIC	8.808	Up-regulation
CMGC_CDK_CDK5_CDK5_ST	Q02078	MEF2A	Q00535	CDK5	S235	R233K	233	Missense	proximal	-2	no	17.057	17.083	EPSD	ICGC;COSMIC	8.808	Up-regulation
CMGC_CDK_CDK5_CDK5_ST	Q02078	MEF2A	Q00535	CDK5	S255	M251V	251	Missense	distal	-4	no	17.774	18.361	EPSD	ICGC;COSMIC	8.808	Up-regulation
CMGC_CDK_CDK5_CDK5_ST	Q02078	MEF2A	Q00535	CDK5	T415	Q422P	422	Missense	distal	7	no	17.087	17.091	EPSD	ICGC;COSMIC	8.808	Up-regulation
CMGC_CDK_CDK5_CDK5_ST	Q02078	MEF2A	Q00535	CDK5	T415	Q421P	421	Missense	distal	6	no	17.087	17.090	EPSD	ICGC;COSMIC	8.808	Up-regulation
CMGC_CDK_CDK5_CDK5_ST	P41236	PPP1R2	Q00535	CDK5	S28	Q31K	31	Missense	distal	3	no	7.930	10.053	EPSD	ICGC	8.808	Gain
CMGC_CDK_CDK5_CDK5_ST	P41236	PPP1R2	Q00535	CDK5	T73	D69G	69	Missense	distal	-4	no	17.425	17.260	PhosphoSitePlus	ICGC	8.808	Down-regulation
CMGC_CDK_CDK5_CDK5_ST	P41236	PPP1R2	Q00535	CDK5	S188	T185K	185	Missense	distal	-3	no	9.014	9.050	EPSD	ICGC	8.808	Up-regulation
CMGC_CDK_CDK5_CDK5_ST	P41236	PPP1R2	Q00535	CDK5	S192	T185K	185	Missense	distal	-7	no	8.896	8.927	EPSD	ICGC	8.808	Up-regulation
CMGC_CDK_CDK5_CDK5_ST	O43464	HTRA2	Q00535	CDK5	S41	G42R	42	Missense	proximal	1	no	-3.585	8.884	EPSD	ICGC	8.808	Gain
CMGC_CDK_CDK5_CDK5_ST	O43464	HTRA2	Q00535	CDK5	T101	R104H	104	Missense	distal	3	no	10.050	9.031	EPSD	ICGC	8.808	Down-regulation
CMGC_CDK_CDK5_CDK5_ST	O43464	HTRA2	Q00535	CDK5	T101	E97D	97	Missense	distal	-4	no	10.050	10.002	EPSD	ICGC	8.808	Down-regulation
CMGC_CDK_CDK5_CDK5_ST	O43464	HTRA2	Q00535	CDK5	S400	R404Q	404	Missense	distal	4	no	18.346	18.299	PhosphoSitePlus	ICGC;COSMIC	8.808	Down-regulation
CMGC_CDK_CDK5_CDK5_ST	O43464	HTRA2	Q00535	CDK5	S400	G399V	399	Missense	proximal	-1	no	18.346	18.348	PhosphoSitePlus	ICGC	8.808	Up-regulation
CMGC_CDK_CDK5_CDK5_ST	P29474	NOS3	Q00535	CDK5	T33	P34S	34	Missense	proximal	1	no	17.026	5.125	EPSD	ICGC;COSMIC	8.808	Loss
CMGC_CDK_CDK5_CDK5_ST	P29474	NOS3	Q00535	CDK5	T33	T33I	33	Missense	central	0	yes	17.026	0.000	EPSD	ICGC	8.808	Loss
CMGC_CDK_CDK5_CDK5_ST	P29474	NOS3	Q00535	CDK5	S53	P47S	47	Missense	distal	-6	no	17.923	17.962	EPSD	ICGC	8.808	Up-regulation
CMGC_CDK_CDK5_CDK5_ST	P29474	NOS3	Q00535	CDK5	S114	K108I	108	Missense	distal	-6	no	17.821	17.706	PhosphoSitePlus	ICGC;COSMIC	8.808	Down-regulation
CMGC_CDK_CDK5_CDK5_ST	P29474	NOS3	Q00535	CDK5	S114	Q110L	110	Missense	distal	-4	no	17.821	17.473	PhosphoSitePlus	ICGC;COSMIC	8.808	Down-regulation
CMGC_CDK_CDK5_CDK5_ST	P29474	NOS3	Q00535	CDK5	S470	E463K	463	Missense	distal	-7	no	15.797	15.859	EPSD	ICGC;COSMIC	8.808	Up-regulation
CMGC_CDK_CDK5_CDK5_ST	P29474	NOS3	Q00535	CDK5	S470	S470F	470	Missense	central	0	yes	15.797	0.000	EPSD	ICGC	8.808	Loss
CMGC_CDK_CDK5_CDK5_ST	P29474	NOS3	Q00535	CDK5	S600	M593I	593	Missense	distal	-7	no	17.366	17.405	EPSD	ICGC	8.808	Up-regulation
CMGC_CDK_CDK5_CDK5_ST	P29474	NOS3	Q00535	CDK5	S600	R602L	602	Missense	proximal	2	no	17.366	17.119	EPSD	ICGC	8.808	Down-regulation
CMGC_CDK_CDK5_CDK5_ST	P29474	NOS3	Q00535	CDK5	S600	S594Y	594	Missense	distal	-6	no	17.366	17.233	EPSD	ICGC;COSMIC	8.808	Down-regulation
CMGC_CDK_CDK5_CDK5_ST	P29474	NOS3	Q00535	CDK5	S600	R602Q	602	Missense	proximal	2	no	17.366	17.227	EPSD	ICGC;COSMIC;CCLE	8.808	Down-regulation
CMGC_CDK_CDK5_CDK5_ST	P29474	NOS3	Q00535	CDK5	S725	R732H	732	Missense	distal	7	no	20.256	20.249	EPSD	ICGC;COSMIC	8.808	Down-regulation
CMGC_CDK_CDK5_CDK5_ST	P29474	NOS3	Q00535	CDK5	S725	R732C	732	Missense	distal	7	no	20.256	20.240	EPSD	ICGC;COSMIC	8.808	Down-regulation
CMGC_CDK_CDK5_CDK5_ST	P29474	NOS3	Q00535	CDK5	S725	A719S	719	Missense	distal	-6	no	20.256	20.370	EPSD	ICGC	8.808	Up-regulation
CMGC_CDK_CDK5_CDK5_ST	P29474	NOS3	Q00535	CDK5	S725	R728Q	728	Missense	distal	3	no	20.256	18.453	EPSD	ICGC	8.808	Down-regulation
CMGC_CDK_CDK5_CDK5_ST	P29474	NOS3	Q00535	CDK5	S725	P726L	726	Missense	proximal	1	no	20.256	8.306	EPSD	ICGC	8.808	Loss
CMGC_CDK_CDK5_CDK5_ST	P29474	NOS3	Q00535	CDK5	S725	R728W	728	Missense	distal	3	no	20.256	18.566	EPSD	ICGC;COSMIC	8.808	Down-regulation
CMGC_CDK_CDK5_CDK5_ST	P29474	NOS3	Q00535	CDK5	S836	V829I	829	Missense	distal	-7	no	18.240	18.224	EPSD	ICGC;COSMIC	8.808	Down-regulation
CMGC_CDK_CDK5_CDK5_ST	P29474	NOS3	Q00535	CDK5	S870	S867F	867	Missense	distal	-3	no	16.752	16.675	EPSD	ICGC	8.808	Down-regulation
CMGC_CDK_CDK5_CDK5_ST	P29474	NOS3	Q00535	CDK5	S981	G986R	986	Missense	distal	5	no	10.918	11.085	EPSD	ICGC;COSMIC	8.808	Up-regulation
CMGC_CDK_CDK5_CDK5_ST	P29474	NOS3	Q00535	CDK5	S981	P988H	988	Missense	distal	7	no	10.918	10.914	EPSD	ICGC;COSMIC	8.808	Down-regulation
CMGC_CDK_CDK5_CDK5_ST	P29474	NOS3	Q00535	CDK5	S1202	D1199H	1199	Missense	distal	-3	no	17.278	17.301	EPSD	ICGC	8.808	Up-regulation
CMGC_CDK_CDK5_CDK5_ST	P26358	DNMT1	Q00535	CDK5	S127	V120L	120	Missense	distal	-7	no	18.776	18.738	EPSD	ICGC	8.808	Down-regulation
CMGC_CDK_CDK5_CDK5_ST	P26358	DNMT1	Q00535	CDK5	T137	P138L	138	Missense	proximal	1	no	19.519	7.570	EPSD	ICGC;COSMIC	8.808	Loss
CMGC_CDK_CDK5_CDK5_ST	P26358	DNMT1	Q00535	CDK5	T137	P135T	135	Missense	proximal	-2	no	19.519	19.380	EPSD	ICGC	8.808	Down-regulation
CMGC_CDK_CDK5_CDK5_ST	P26358	DNMT1	Q00535	CDK5	T137	R139K	139	Missense	proximal	2	no	19.519	19.568	EPSD	ICGC;COSMIC	8.808	Up-regulation
CMGC_CDK_CDK5_CDK5_ST	P26358	DNMT1	Q00535	CDK5	T137	R139S	139	Missense	proximal	2	no	19.519	19.420	EPSD	ICGC;COSMIC	8.808	Down-regulation
CMGC_CDK_CDK5_CDK5_ST	P26358	DNMT1	Q00535	CDK5	T137	R136H	136	Missense	proximal	-1	no	19.519	19.517	EPSD	ICGC;COSMIC	8.808	Down-regulation
CMGC_CDK_CDK5_CDK5_ST	P26358	DNMT1	Q00535	CDK5	S152	A147T	147	Missense	distal	-5	no	18.160	18.316	EPSD	ICGC	8.808	Up-regulation
CMGC_CDK_CDK5_CDK5_ST	P26358	DNMT1	Q00535	CDK5	S154	A147T	147	Missense	distal	-7	no	17.369	17.408	PhosphoSitePlus	ICGC	8.808	Up-regulation
CMGC_CDK_CDK5_CDK5_ST	Q13315	ATM	Q00535	CDK5	S89	V82L	82	Missense	distal	-7	no	11.716	11.678	EPSD	ICGC	8.808	Down-regulation
CMGC_CDK_CDK5_CDK5_ST	Q13315	ATM	Q00535	CDK5	S89	Q91H	91	Missense	proximal	2	no	11.716	11.741	EPSD	ICGC;COSMIC	8.808	Up-regulation
CMGC_CDK_CDK5_CDK5_ST	Q13315	ATM	Q00535	CDK5	T297	Q298K	298	Missense	proximal	1	no	10.053	0.851	EPSD	ICGC;COSMIC	8.808	Loss
CMGC_CDK_CDK5_CDK5_ST	Q13315	ATM	Q00535	CDK5	T373	S378R	378	Missense	distal	5	no	9.053	9.116	EPSD	ICGC;COSMIC	8.808	Up-regulation
CMGC_CDK_CDK5_CDK5_ST	Q13315	ATM	Q00535	CDK5	T373	S367F	367	Missense	distal	-6	no	9.053	8.880	EPSD	ICGC;COSMIC	8.808	Down-regulation
CMGC_CDK_CDK5_CDK5_ST	Q13315	ATM	Q00535	CDK5	S794	N796T	796	Missense	proximal	2	no	19.473	19.544	PhosphoSitePlus	ICGC;COSMIC	8.808	Up-regulation
CMGC_CDK_CDK5_CDK5_ST	Q13315	ATM	Q00535	CDK5	S1105	R1106S	1106	Missense	proximal	1	no	9.089	6.135	EPSD	ICGC	8.808	Loss
CMGC_CDK_CDK5_CDK5_ST	Q13315	ATM	Q00535	CDK5	S1770	L1764Q	1764	Missense	distal	-6	no	11.116	11.187	EPSD	ICGC;COSMIC	8.808	Up-regulation
CMGC_CDK_CDK5_CDK5_ST	Q13315	ATM	Q00535	CDK5	S1881	Q1879K	1879	Missense	proximal	-2	no	8.720	8.883	EPSD	ICGC;COSMIC	8.808	Gain
CMGC_CDK_CDK5_CDK5_ST	Q13315	ATM	Q00535	CDK5	T1885	Q1879K	1879	Missense	distal	-6	no	17.580	17.674	EPSD	ICGC;COSMIC	8.808	Up-regulation
CMGC_CDK_CDK5_CDK5_ST	Q13315	ATM	Q00535	CDK5	S1981	S1988I	1988	Missense	distal	7	no	9.165	9.159	EPSD	ICGC;COSMIC	8.808	Down-regulation
CMGC_CDK_CDK5_CDK5_ST	Q13315	ATM	Q00535	CDK5	S1981	E1979V	1979	Missense	proximal	-2	no	9.165	9.426	EPSD	ICGC	8.808	Up-regulation
CMGC_CDK_CDK5_CDK5_ST	Q13315	ATM	Q00535	CDK5	T2031	L2033V	2033	Missense	proximal	2	no	9.258	9.392	EPSD	ICGC;COSMIC	8.808	Up-regulation
CMGC_CDK_CDK5_CDK5_ST	Q13315	ATM	Q00535	CDK5	T2031	P2029L	2029	Missense	proximal	-2	no	9.258	8.843	EPSD	ICGC	8.808	Down-regulation
CMGC_CDK_CDK5_CDK5_ST	Q13315	ATM	Q00535	CDK5	T2031	K2025N	2025	Missense	distal	-6	no	9.258	9.157	EPSD	ICGC	8.808	Down-regulation
CMGC_CDK_CDK5_CDK5_ST	Q13315	ATM	Q00535	CDK5	S2592	D2597N	2597	Missense	distal	5	no	8.806	8.875	EPSD	ICGC;COSMIC	8.808	Gain
CMGC_CDK_CDK5_CDK5_ST	Q9UQL6	HDAC5	Q00535	CDK5	S224	S225R	225	Missense	proximal	1	no	5.873	8.827	EPSD	ICGC;COSMIC	8.808	Gain
CMGC_CDK_CDK5_CDK5_ST	Q9UQL6	HDAC5	Q00535	CDK5	S225	S225R	225	Missense	central	0	yes	16.755	0.000	EPSD	ICGC;COSMIC	8.808	Loss
CMGC_CDK_CDK5_CDK5_ST	Q5S007	LRRK2	Q00535	CDK5	T213	A211V	211	Missense	proximal	-2	no	9.203	9.399	EPSD	ICGC;COSMIC	8.808	Up-regulation
CMGC_CDK_CDK5_CDK5_ST	Q5S007	LRRK2	Q00535	CDK5	S926	C925Y	925	Missense	proximal	-1	no	15.919	15.920	EPSD	ICGC;COSMIC;GDSC	8.808	Up-regulation
CMGC_CDK_CDK5_CDK5_ST	Q5S007	LRRK2	Q00535	CDK5	S926	V921L	921	Missense	distal	-5	no	15.919	15.756	EPSD	ICGC	8.808	Down-regulation
CMGC_CDK_CDK5_CDK5_ST	Q5S007	LRRK2	Q00535	CDK5	S926	R931S	931	Missense	distal	5	no	15.919	15.856	EPSD	ICGC;COSMIC	8.808	Down-regulation
CMGC_CDK_CDK5_CDK5_ST	Q5S007	LRRK2	Q00535	CDK5	S1124	P1125L	1125	Missense	proximal	1	no	19.561	7.612	EPSD	ICGC	8.808	Loss
CMGC_CDK_CDK5_CDK5_ST	Q5S007	LRRK2	Q00535	CDK5	S1445	P1446L	1446	Missense	proximal	1	no	17.728	5.778	EPSD	ICGC;COSMIC;GDSC	8.808	Loss
CMGC_CDK_CDK5_CDK5_ST	Q5S007	LRRK2	Q00535	CDK5	S1457	E1459K	1459	Missense	proximal	2	no	9.176	9.426	EPSD	ICGC	8.808	Up-regulation
CMGC_CDK_CDK5_CDK5_ST	Q5S007	LRRK2	Q00535	CDK5	S1457	D1458Y	1458	Missense	proximal	1	no	9.176	-0.094	EPSD	ICGC	8.808	Loss
CMGC_CDK_CDK5_CDK5_ST	Q5S007	LRRK2	Q00535	CDK5	S1457	V1456F	1456	Missense	proximal	-1	no	9.176	9.170	EPSD	ICGC	8.808	Down-regulation
CMGC_CDK_CDK5_CDK5_ST	Q5S007	LRRK2	Q00535	CDK5	S1457	R1462L	1462	Missense	distal	5	no	9.176	8.928	EPSD	ICGC	8.808	Down-regulation
CMGC_CDK_CDK5_CDK5_ST	Q5S007	LRRK2	Q00535	CDK5	S1627	S1627L	1627	Missense	central	0	yes	9.543	0.000	PhosphoSitePlus	ICGC;COSMIC	8.808	Loss
CMGC_CDK_CDK5_CDK5_ST	Q5S007	LRRK2	Q00535	CDK5	S1627	G1624V	1624	Missense	distal	-3	no	9.543	9.575	PhosphoSitePlus	ICGC	8.808	Up-regulation
CMGC_CDK_CDK5_CDK5_ST	Q5S007	LRRK2	Q00535	CDK5	S1627	R1628C	1628	Missense	proximal	1	no	9.543	-2.184	PhosphoSitePlus	ICGC;COSMIC	8.808	Loss
CMGC_CDK_CDK5_CDK5_ST	Q5S007	LRRK2	Q00535	CDK5	S1627	D1630Y	1630	Missense	distal	3	no	9.543	9.388	PhosphoSitePlus	ICGC;COSMIC	8.808	Down-regulation
CMGC_CDK_CDK5_CDK5_ST	Q5S007	LRRK2	Q00535	CDK5	T1967	L1970V	1970	Missense	distal	3	no	8.235	9.314	EPSD	ICGC;COSMIC	8.808	Gain
CMGC_CDK_CDK5_CDK5_ST	Q5S007	LRRK2	Q00535	CDK5	T1967	L1970I	1970	Missense	distal	3	no	8.235	8.865	EPSD	ICGC;COSMIC	8.808	Gain
CMGC_CDK_CDK5_CDK5_ST	Q5S007	LRRK2	Q00535	CDK5	T2035	F2038V	2038	Missense	distal	3	no	16.072	17.277	EPSD	ICGC	8.808	Up-regulation
CMGC_CDK_CDK5_CDK5_ST	Q5S007	LRRK2	Q00535	CDK5	T2035	G2034C	2034	Missense	proximal	-1	no	16.072	16.070	EPSD	ICGC;COSMIC	8.808	Down-regulation
CMGC_CDK_CDK5_CDK5_ST	Q5S007	LRRK2	Q00535	CDK5	T2035	P2036Q	2036	Missense	proximal	1	no	16.072	7.096	EPSD	ICGC;COSMIC	8.808	Loss
CMGC_CDK_CDK5_CDK5_ST	Q5S007	LRRK2	Q00535	CDK5	T2035	G2028W	2028	Missense	distal	-7	no	16.072	16.074	EPSD	ICGC;COSMIC	8.808	Up-regulation
CMGC_CDK_CDK5_CDK5_ST	O15169	AXIN1	Q00535	CDK5	T60	G54A	54	Missense	distal	-6	no	18.864	18.844	EPSD	ICGC;COSMIC	8.808	Down-regulation
CMGC_CDK_CDK5_CDK5_ST	O15169	AXIN1	Q00535	CDK5	T60	G54S	54	Missense	distal	-6	no	18.864	18.958	EPSD	ICGC;COSMIC	8.808	Up-regulation
CMGC_CDK_CDK5_CDK5_ST	O15169	AXIN1	Q00535	CDK5	S77	T79A	79	Missense	proximal	2	no	17.831	17.712	EPSD	ICGC	8.808	Down-regulation
CMGC_CDK_CDK5_CDK5_ST	O15169	AXIN1	Q00535	CDK5	S77	T79I	79	Missense	proximal	2	no	17.831	17.736	EPSD	ICGC;COSMIC	8.808	Down-regulation
CMGC_CDK_CDK5_CDK5_ST	O15169	AXIN1	Q00535	CDK5	T79	T79A	79	Missense	central	0	yes	16.806	0.000	EPSD	ICGC	8.808	Loss
CMGC_CDK_CDK5_CDK5_ST	O15169	AXIN1	Q00535	CDK5	T79	T79I	79	Missense	central	0	yes	16.806	0.000	EPSD	ICGC;COSMIC	8.808	Loss
CMGC_CDK_CDK5_CDK5_ST	O15169	AXIN1	Q00535	CDK5	S217	P218L	218	Missense	proximal	1	no	18.166	6.217	EPSD	ICGC	8.808	Loss
CMGC_CDK_CDK5_CDK5_ST	O15169	AXIN1	Q00535	CDK5	S282	S283N	283	Missense	proximal	1	no	7.815	10.478	EPSD	ICGC;COSMIC	8.808	Gain
CMGC_CDK_CDK5_CDK5_ST	O15169	AXIN1	Q00535	CDK5	S283	Y286H	286	Missense	distal	3	no	8.857	10.024	EPSD	ICGC;COSMIC	8.808	Up-regulation
CMGC_CDK_CDK5_CDK5_ST	O15169	AXIN1	Q00535	CDK5	S283	S283N	283	Missense	central	0	yes	8.857	0.000	EPSD	ICGC;COSMIC	8.808	Loss
CMGC_CDK_CDK5_CDK5_ST	O15169	AXIN1	Q00535	CDK5	S283	V280I	280	Missense	distal	-3	no	8.857	8.842	EPSD	ICGC;COSMIC	8.808	Down-regulation
CMGC_CDK_CDK5_CDK5_ST	O15169	AXIN1	Q00535	CDK5	S283	P278L	278	Missense	distal	-5	no	8.857	8.659	EPSD	ICGC;COSMIC;GDSC	8.808	Loss
CMGC_CDK_CDK5_CDK5_ST	O15169	AXIN1	Q00535	CDK5	T481	R484S	484	Missense	distal	3	no	19.083	17.665	PhosphoSitePlus	ICGC	8.808	Down-regulation
CMGC_CDK_CDK5_CDK5_ST	O15169	AXIN1	Q00535	CDK5	T481	H474Q	474	Missense	distal	-7	no	19.083	19.094	PhosphoSitePlus	ICGC	8.808	Up-regulation
CMGC_CDK_CDK5_CDK5_ST	O15169	AXIN1	Q00535	CDK5	T481	G483S	483	Missense	proximal	2	no	19.083	19.156	PhosphoSitePlus	ICGC;COSMIC	8.808	Up-regulation
CMGC_CDK_CDK5_CDK5_ST	O15169	AXIN1	Q00535	CDK5	S486	R484S	484	Missense	proximal	-2	no	18.917	18.873	EPSD	ICGC	8.808	Down-regulation
CMGC_CDK_CDK5_CDK5_ST	O15169	AXIN1	Q00535	CDK5	S486	H491N	491	Missense	distal	5	no	18.917	18.893	EPSD	ICGC	8.808	Down-regulation
CMGC_CDK_CDK5_CDK5_ST	O15169	AXIN1	Q00535	CDK5	S486	R492C	492	Missense	distal	6	no	18.917	18.894	EPSD	ICGC;COSMIC;CCLE	8.808	Down-regulation
CMGC_CDK_CDK5_CDK5_ST	O15169	AXIN1	Q00535	CDK5	S486	G483S	483	Missense	distal	-3	no	18.917	18.958	EPSD	ICGC;COSMIC	8.808	Up-regulation
CMGC_CDK_CDK5_CDK5_ST	O15169	AXIN1	Q00535	CDK5	S493	H491N	491	Missense	proximal	-2	no	17.697	17.801	EPSD	ICGC	8.808	Up-regulation
CMGC_CDK_CDK5_CDK5_ST	O15169	AXIN1	Q00535	CDK5	S493	R492C	492	Missense	proximal	-1	no	17.697	17.691	EPSD	ICGC;COSMIC;CCLE	8.808	Down-regulation
CMGC_CDK_CDK5_CDK5_ST	O15169	AXIN1	Q00535	CDK5	S493	P494Q	494	Missense	proximal	1	no	17.697	8.721	EPSD	ICGC	8.808	Loss
CMGC_CDK_CDK5_CDK5_ST	O15169	AXIN1	Q00535	CDK5	S542	V539I	539	Missense	distal	-3	no	8.891	8.875	EPSD	ICGC;COSMIC	8.808	Down-regulation
CMGC_CDK_CDK5_CDK5_ST	O15169	AXIN1	Q00535	CDK5	S542	H538Q	538	Missense	distal	-4	no	8.891	9.100	EPSD	ICGC	8.808	Up-regulation
CMGC_CDK_CDK5_CDK5_ST	O15169	AXIN1	Q00535	CDK5	S542	T543A	543	Missense	proximal	1	no	8.891	8.351	EPSD	ICGC;COSMIC	8.808	Loss
CMGC_CDK_CDK5_CDK5_ST	O15169	AXIN1	Q00535	CDK5	S644	H651Q	651	Missense	distal	7	no	9.494	9.495	EPSD	ICGC;COSMIC	8.808	Up-regulation
CMGC_CDK_CDK5_CDK5_ST	O15169	AXIN1	Q00535	CDK5	S644	R647C	647	Missense	distal	3	no	9.494	7.198	EPSD	ICGC;COSMIC	8.808	Loss
CMGC_CDK_CDK5_CDK5_ST	P49768	PSEN1	Q00535	CDK5	S51	E48D	48	Missense	distal	-3	no	9.934	9.932	EPSD	ICGC;COSMIC	8.808	Down-regulation
CMGC_CDK_CDK5_CDK5_ST	P49768	PSEN1	Q00535	CDK5	S51	Q56K	56	Missense	distal	5	no	9.934	10.134	EPSD	ICGC;COSMIC	8.808	Up-regulation
CMGC_CDK_CDK5_CDK5_ST	P02545	LMNA	Q00535	CDK5	T10	G13E	13	Missense	distal	3	no	9.537	8.952	EPSD	ICGC	8.808	Down-regulation
CMGC_CDK_CDK5_CDK5_ST	P02545	LMNA	Q00535	CDK5	T19	S22L	22	Missense	distal	3	no	18.613	17.561	EPSD	ICGC	8.808	Down-regulation
CMGC_CDK_CDK5_CDK5_ST	P02545	LMNA	Q00535	CDK5	T19	G13E	13	Missense	distal	-6	no	18.613	18.620	EPSD	ICGC	8.808	Up-regulation
CMGC_CDK_CDK5_CDK5_ST	P02545	LMNA	Q00535	CDK5	S22	S22L	22	Missense	central	0	yes	21.002	0.000	EPSD	ICGC	8.808	Loss
CMGC_CDK_CDK5_CDK5_ST	P02545	LMNA	Q00535	CDK5	S22	T27I	27	Missense	distal	5	no	21.002	20.913	EPSD	ICGC;COSMIC	8.808	Down-regulation
CMGC_CDK_CDK5_CDK5_ST	P02545	LMNA	Q00535	CDK5	T24	S22L	22	Missense	proximal	-2	no	10.054	9.738	EPSD	ICGC	8.808	Down-regulation
CMGC_CDK_CDK5_CDK5_ST	P02545	LMNA	Q00535	CDK5	T24	E31K	31	Missense	distal	7	no	10.054	10.070	EPSD	ICGC;COSMIC	8.808	Up-regulation
CMGC_CDK_CDK5_CDK5_ST	P02545	LMNA	Q00535	CDK5	T24	T27I	27	Missense	distal	3	no	10.054	9.076	EPSD	ICGC;COSMIC	8.808	Down-regulation
CMGC_CDK_CDK5_CDK5_ST	P02545	LMNA	Q00535	CDK5	S71	E65K	65	Missense	distal	-6	no	8.851	8.980	EPSD	ICGC	8.808	Up-regulation
CMGC_CDK_CDK5_CDK5_ST	P02545	LMNA	Q00535	CDK5	S507	G503S	503	Missense	distal	-4	no	17.593	18.435	EPSD	ICGC;COSMIC	8.808	Up-regulation
CMGC_CDK_CDK5_CDK5_ST	Q9Y490	TLN1	Q00535	CDK5	T354	I348M	348	Missense	distal	-6	no	9.636	9.560	EPSD	ICGC;COSMIC	8.808	Down-regulation
CMGC_CDK_CDK5_CDK5_ST	Q9Y490	TLN1	Q00535	CDK5	T354	A361P	361	Missense	distal	7	no	9.636	9.646	EPSD	ICGC;COSMIC	8.808	Up-regulation
CMGC_CDK_CDK5_CDK5_ST	Q9Y490	TLN1	Q00535	CDK5	S362	L368M	368	Missense	distal	6	no	17.595	17.593	EPSD	ICGC;COSMIC	8.808	Down-regulation
CMGC_CDK_CDK5_CDK5_ST	Q9Y490	TLN1	Q00535	CDK5	S362	A361P	361	Missense	proximal	-1	no	17.595	17.599	EPSD	ICGC;COSMIC	8.808	Up-regulation
CMGC_CDK_CDK5_CDK5_ST	Q9Y490	TLN1	Q00535	CDK5	S973	Q976K	976	Missense	distal	3	no	8.050	10.172	EPSD	ICGC;COSMIC	8.808	Gain
CMGC_CDK_CDK5_CDK5_ST	Q9Y490	TLN1	Q00535	CDK5	S979	P977H	977	Missense	proximal	-2	no	17.479	17.163	EPSD	ICGC	8.808	Down-regulation
CMGC_CDK_CDK5_CDK5_ST	Q9Y490	TLN1	Q00535	CDK5	S979	A975T	975	Missense	distal	-4	no	17.479	17.879	EPSD	ICGC;COSMIC	8.808	Up-regulation
CMGC_CDK_CDK5_CDK5_ST	Q9Y490	TLN1	Q00535	CDK5	S979	Q976K	976	Missense	distal	-3	no	17.479	17.525	EPSD	ICGC;COSMIC	8.808	Up-regulation
CMGC_CDK_CDK5_CDK5_ST	Q9Y490	TLN1	Q00535	CDK5	S979	A982T	982	Missense	distal	3	no	17.479	18.260	EPSD	ICGC;COSMIC;GDSC;CCLE	8.808	Up-regulation
CMGC_CDK_CDK5_CDK5_ST	Q9Y490	TLN1	Q00535	CDK5	S1021	A1017V	1017	Missense	distal	-4	no	8.867	9.286	EPSD	ICGC	8.808	Up-regulation
CMGC_CDK_CDK5_CDK5_ST	Q9Y490	TLN1	Q00535	CDK5	S1231	S1227L	1227	Missense	distal	-4	no	9.006	8.187	EPSD	ICGC;COSMIC	8.808	Loss
CMGC_CDK_CDK5_CDK5_ST	Q9Y490	TLN1	Q00535	CDK5	S1231	G1233V	1233	Missense	proximal	2	no	9.006	9.066	EPSD	ICGC;COSMIC	8.808	Up-regulation
CMGC_CDK_CDK5_CDK5_ST	Q9Y490	TLN1	Q00535	CDK5	S1260	A1259D	1259	Missense	proximal	-1	no	9.702	9.703	EPSD	ICGC;COSMIC	8.808	Up-regulation
CMGC_CDK_CDK5_CDK5_ST	Q9Y490	TLN1	Q00535	CDK5	S1260	R1261W	1261	Missense	proximal	1	no	9.702	-0.156	EPSD	ICGC;CCLE	8.808	Loss
CMGC_CDK_CDK5_CDK5_ST	Q9Y490	TLN1	Q00535	CDK5	T1263	A1259D	1259	Missense	distal	-4	no	16.873	17.098	EPSD	ICGC;COSMIC	8.808	Up-regulation
CMGC_CDK_CDK5_CDK5_ST	Q9Y490	TLN1	Q00535	CDK5	T1263	R1261W	1261	Missense	proximal	-2	no	16.873	16.500	EPSD	ICGC;CCLE	8.808	Down-regulation
CMGC_CDK_CDK5_CDK5_ST	Q9Y490	TLN1	Q00535	CDK5	S1303	S1309Y	1309	Missense	distal	6	no	10.387	10.372	EPSD	ICGC;COSMIC	8.808	Down-regulation
CMGC_CDK_CDK5_CDK5_ST	Q9Y490	TLN1	Q00535	CDK5	T1517	R1515H	1515	Missense	proximal	-2	no	9.320	9.058	EPSD	ICGC	8.808	Down-regulation
CMGC_CDK_CDK5_CDK5_ST	Q9Y490	TLN1	Q00535	CDK5	T1517	A1514D	1514	Missense	distal	-3	no	9.320	9.326	EPSD	ICGC;COSMIC	8.808	Up-regulation
CMGC_CDK_CDK5_CDK5_ST	Q9Y490	TLN1	Q00535	CDK5	T1517	P1519H	1519	Missense	proximal	2	no	9.320	9.286	EPSD	ICGC	8.808	Down-regulation
CMGC_CDK_CDK5_CDK5_ST	Q9Y490	TLN1	Q00535	CDK5	S1589	I1588V	1588	Missense	proximal	-1	no	18.737	18.738	EPSD	ICGC;COSMIC	8.808	Up-regulation
CMGC_CDK_CDK5_CDK5_ST	Q9Y490	TLN1	Q00535	CDK5	S1637	S1631L	1631	Missense	distal	-6	no	9.394	9.272	EPSD	ICGC	8.808	Down-regulation
CMGC_CDK_CDK5_CDK5_ST	Q9Y490	TLN1	Q00535	CDK5	S1694	A1688S	1688	Missense	distal	-6	no	9.218	9.332	EPSD	ICGC;COSMIC	8.808	Up-regulation
CMGC_CDK_CDK5_CDK5_ST	Q9Y490	TLN1	Q00535	CDK5	S1694	A1697D	1697	Missense	distal	3	no	9.218	8.828	EPSD	ICGC	8.808	Down-regulation
CMGC_CDK_CDK5_CDK5_ST	Q9Y490	TLN1	Q00535	CDK5	S1875	E1880Q	1880	Missense	distal	5	no	8.840	8.891	EPSD	ICGC;COSMIC	8.808	Up-regulation
CMGC_CDK_CDK5_CDK5_ST	Q9Y490	TLN1	Q00535	CDK5	S1878	E1880Q	1880	Missense	proximal	2	no	18.329	18.391	EPSD	ICGC;COSMIC	8.808	Up-regulation
CMGC_CDK_CDK5_CDK5_ST	Q9Y490	TLN1	Q00535	CDK5	S1878	P1884R	1884	Missense	distal	6	no	18.329	18.337	EPSD	ICGC;COSMIC	8.808	Up-regulation
CMGC_CDK_CDK5_CDK5_ST	Q9Y490	TLN1	Q00535	CDK5	S2162	C2161S	2161	Missense	proximal	-1	no	17.127	17.134	EPSD	ICGC;COSMIC	8.808	Up-regulation
CMGC_CDK_CDK5_CDK5_ST	Q9Y490	TLN1	Q00535	CDK5	S2162	T2169I	2169	Missense	distal	7	no	17.127	17.122	EPSD	ICGC	8.808	Down-regulation
CMGC_CDK_CDK5_CDK5_ST	Q9Y490	TLN1	Q00535	CDK5	T2171	T2169I	2169	Missense	proximal	-2	no	16.394	16.212	EPSD	ICGC	8.808	Down-regulation
CMGC_CDK_CDK5_CDK5_ST	O94916	NFAT5	Q00535	CDK5	S17	L15P	15	Missense	proximal	-2	no	18.675	19.090	EPSD	ICGC;COSMIC	8.808	Up-regulation
CMGC_CDK_CDK5_CDK5_ST	O94916	NFAT5	Q00535	CDK5	S134	R138Q	138	Missense	distal	4	no	9.087	9.040	EPSD	ICGC;COSMIC	8.808	Down-regulation
CMGC_CDK_CDK5_CDK5_ST	O94916	NFAT5	Q00535	CDK5	T135	R138Q	138	Missense	distal	3	no	19.268	17.465	PhosphoSitePlus	ICGC;COSMIC	8.808	Down-regulation
CMGC_CDK_CDK5_CDK5_ST	O94916	NFAT5	Q00535	CDK5	S145	R138Q	138	Missense	distal	-7	no	17.438	17.418	EPSD	ICGC;COSMIC	8.808	Down-regulation
CMGC_CDK_CDK5_CDK5_ST	O94916	NFAT5	Q00535	CDK5	T608	I602V	602	Missense	distal	-6	no	17.221	17.248	EPSD	ICGC;COSMIC	8.808	Up-regulation
CMGC_CDK_CDK5_CDK5_ST	O94916	NFAT5	Q00535	CDK5	S744	Q747L	747	Missense	distal	3	no	16.411	15.744	EPSD	ICGC	8.808	Down-regulation
CMGC_CDK_CDK5_CDK5_ST	Q15833	STXBP2	Q00535	CDK5	S16	G17R	17	Missense	proximal	1	no	-2.268	10.200	EPSD	ICGC;COSMIC	8.808	Gain
CMGC_CDK_CDK5_CDK5_ST	Q15833	STXBP2	Q00535	CDK5	S21	I14F	14	Missense	distal	-7	no	9.356	9.306	EPSD	ICGC;COSMIC	8.808	Down-regulation
CMGC_CDK_CDK5_CDK5_ST	Q15833	STXBP2	Q00535	CDK5	S21	V22F	22	Missense	proximal	1	no	9.356	-1.713	EPSD	ICGC	8.808	Loss
CMGC_CDK_CDK5_CDK5_ST	Q15833	STXBP2	Q00535	CDK5	S21	G17R	17	Missense	distal	-4	no	9.356	9.736	EPSD	ICGC;COSMIC	8.808	Up-regulation
CMGC_CDK_CDK5_CDK5_ST	Q15833	STXBP2	Q00535	CDK5	S78	E81K	81	Missense	distal	3	no	16.781	19.067	EPSD	ICGC;COSMIC	8.808	Up-regulation
CMGC_CDK_CDK5_CDK5_ST	Q15833	STXBP2	Q00535	CDK5	S508	A514S	514	Missense	distal	6	no	8.814	8.826	EPSD	ICGC;COSMIC	8.808	Up-regulation
CMGC_CDK_CDK5_CDK5_ST	P08670	VIM	Q00535	CDK5	S22	P24L	24	Missense	proximal	2	no	9.998	9.833	EPSD	ICGC;COSMIC	8.808	Down-regulation
CMGC_CDK_CDK5_CDK5_ST	P08670	VIM	Q00535	CDK5	S22	P18T	18	Missense	distal	-4	no	9.998	9.842	EPSD	ICGC;COSMIC	8.808	Down-regulation
CMGC_CDK_CDK5_CDK5_ST	P08670	VIM	Q00535	CDK5	S56	S55L	55	Missense	proximal	-1	no	16.965	16.959	PhosphoSitePlus	ICGC	8.808	Down-regulation
CMGC_CDK_CDK5_CDK5_ST	P08670	VIM	Q00535	CDK5	S56	A54G	54	Missense	proximal	-2	no	16.965	16.878	PhosphoSitePlus	ICGC	8.808	Down-regulation
CMGC_CDK_CDK5_CDK5_ST	P08670	VIM	Q00535	CDK5	S56	A62V	62	Missense	distal	6	no	16.965	16.974	PhosphoSitePlus	ICGC	8.808	Up-regulation
CMGC_CDK_CDK5_CDK5_ST	P08670	VIM	Q00535	CDK5	T94	E95Q	95	Missense	proximal	1	no	-4.021	9.214	EPSD	ICGC;COSMIC	8.808	Gain
CMGC_CDK_CDK5_CDK5_ST	P08670	VIM	Q00535	CDK5	T101	E95Q	95	Missense	distal	-6	no	9.368	9.404	EPSD	ICGC;COSMIC	8.808	Up-regulation
CMGC_CDK_CDK5_CDK5_ST	P08670	VIM	Q00535	CDK5	T101	V105M	105	Missense	distal	4	no	9.368	9.292	EPSD	ICGC;GDSC	8.808	Down-regulation
CMGC_CDK_CDK5_CDK5_ST	P08670	VIM	Q00535	CDK5	T449	D451Y	451	Missense	proximal	2	no	9.448	9.403	EPSD	ICGC;COSMIC	8.808	Down-regulation
CMGC_CDK_CDK5_CDK5_ST	P08670	VIM	Q00535	CDK5	T449	R450G	450	Missense	proximal	1	no	9.448	-3.020	EPSD	ICGC;COSMIC	8.808	Loss
CMGC_CDK_CDK5_CDK5_ST	P08670	VIM	Q00535	CDK5	T449	V447F	447	Missense	proximal	-2	no	9.448	8.972	EPSD	ICGC	8.808	Down-regulation
CMGC_CDK_CDK5_CDK5_ST	P08670	VIM	Q00535	CDK5	S459	D463N	463	Missense	distal	4	no	9.622	9.652	EPSD	ICGC;COSMIC	8.808	Up-regulation
CMGC_CDK_CDK5_CDK5_ST	P08670	VIM	Q00535	CDK5	S459	S459C	459	Missense	central	0	yes	9.622	0.000	EPSD	ICGC;COSMIC	8.808	Loss
CAMK_CAMK1_PNCK_ST	P08238	HSP90AB1	Q6P2M8	PNCK	S58	D52Y	52	Missense	distal	-6	no	2.362	2.414	EPSD	ICGC	1.882	Up-regulation
CAMK_CAMK1_PNCK_ST	P08238	HSP90AB1	Q6P2M8	PNCK	S58	R55L	55	Missense	distal	-3	no	2.362	2.485	EPSD	ICGC	1.882	Up-regulation
CAMK_CAMK1_PNCK_ST	P08238	HSP90AB1	Q6P2M8	PNCK	T89	M93I	93	Missense	distal	4	no	7.022	7.104	PhosphoSitePlus	ICGC;COSMIC	1.882	Up-regulation
CAMK_CAMK1_PNCK_ST	P08238	HSP90AB1	Q6P2M8	PNCK	T94	M93I	93	Missense	proximal	-1	no	2.016	1.959	EPSD	ICGC;COSMIC	1.882	Down-regulation
CAMK_CAMK1_PNCK_ST	P08238	HSP90AB1	Q6P2M8	PNCK	S124	M125V	125	Missense	proximal	1	no	2.320	2.308	EPSD	ICGC	1.882	Down-regulation
CAMK_CAMK1_PNCK_ST	P08238	HSP90AB1	Q6P2M8	PNCK	S124	Q118L	118	Missense	distal	-6	no	2.320	2.649	EPSD	ICGC	1.882	Up-regulation
CAMK_CAMK1_PNCK_ST	P08238	HSP90AB1	Q6P2M8	PNCK	S255	D252Y	252	Missense	distal	-3	no	2.222	2.001	EPSD	ICGC	1.882	Down-regulation
CAMK_CAMK1_PNCK_ST	P08238	HSP90AB1	Q6P2M8	PNCK	S255	G262S	262	Missense	distal	7	no	2.222	2.032	EPSD	ICGC;COSMIC	1.882	Down-regulation
CAMK_CAMK1_PNCK_ST	P08238	HSP90AB1	Q6P2M8	PNCK	S261	G262S	262	Missense	proximal	1	no	2.394	2.343	EPSD	ICGC;COSMIC	1.882	Down-regulation
CAMK_CAMK1_PNCK_ST	P08238	HSP90AB1	Q6P2M8	PNCK	S365	V360L	360	Missense	distal	-5	no	1.942	2.278	EPSD	ICGC	1.882	Up-regulation
CAMK_CAMK1_PNCK_ST	P08238	HSP90AB1	Q6P2M8	PNCK	S365	L369F	369	Missense	distal	4	no	1.942	1.662	EPSD	ICGC	1.882	Loss
CAMK_CAMK1_PNCK_ST	P08238	HSP90AB1	Q6P2M8	PNCK	S365	R359L	359	Missense	distal	-6	no	1.942	2.289	EPSD	ICGC	1.882	Up-regulation
CAMK_CAMK1_PNCK_ST	P08238	HSP90AB1	Q6P2M8	PNCK	S365	P371T	371	Missense	distal	6	no	1.942	1.831	EPSD	ICGC;COSMIC	1.882	Loss
CAMK_CAMK1_PNCK_ST	P08238	HSP90AB1	Q6P2M8	PNCK	S365	R358H	358	Missense	distal	-7	no	1.942	1.970	EPSD	ICGC;COSMIC	1.882	Up-regulation
CAMK_CAMK1_PNCK_ST	P08238	HSP90AB1	Q6P2M8	PNCK	S383	V381F	381	Missense	proximal	-2	no	6.825	6.735	EPSD	ICGC;COSMIC	1.882	Down-regulation
CAMK_CAMK1_PNCK_ST	P08238	HSP90AB1	Q6P2M8	PNCK	S383	I390M	390	Missense	distal	7	no	6.825	6.429	EPSD	ICGC;COSMIC	1.882	Down-regulation
CAMK_CAMK1_PNCK_ST	P08238	HSP90AB1	Q6P2M8	PNCK	S383	S383Y	383	Missense	central	0	yes	6.825	0.000	EPSD	ICGC;GDSC;CCLE	1.882	Loss
CAMK_CAMK1_PNCK_ST	P08238	HSP90AB1	Q6P2M8	PNCK	S398	I400V	400	Missense	proximal	2	no	2.677	2.452	EPSD	ICGC;COSMIC	1.882	Down-regulation
CAMK_CAMK1_PNCK_ST	P08238	HSP90AB1	Q6P2M8	PNCK	S398	R405C	405	Missense	distal	7	no	2.677	2.961	EPSD	ICGC	1.882	Up-regulation
CAMK_CAMK1_PNCK_ST	P08238	HSP90AB1	Q6P2M8	PNCK	S434	K428T	428	Missense	distal	-6	no	1.911	2.265	EPSD	ICGC	1.882	Up-regulation
CAMK_CAMK1_PNCK_ST	P08238	HSP90AB1	Q6P2M8	PNCK	S482	R475C	475	Missense	distal	-7	no	2.678	2.717	EPSD	ICGC;COSMIC	1.882	Up-regulation
CAMK_CAMK1_PNCK_ST	P08238	HSP90AB1	Q6P2M8	PNCK	S482	R475H	475	Missense	distal	-7	no	2.678	2.706	EPSD	ICGC;COSMIC	1.882	Up-regulation
CAMK_CAMK1_PNCK_ST	P08238	HSP90AB1	Q6P2M8	PNCK	S482	I486V	486	Missense	distal	4	no	2.678	2.409	EPSD	ICGC;COSMIC	1.882	Down-regulation
CAMK_CAMK1_PNCK_ST	P08238	HSP90AB1	Q6P2M8	PNCK	S482	G488V	488	Missense	distal	6	no	2.678	2.761	EPSD	ICGC;COSMIC	1.882	Up-regulation
CAMK_CAMK1_PNCK_ST	P07900	HSP90AA1	Q6P2M8	PNCK	S63	D66Y	66	Missense	distal	3	no	2.429	2.343	EPSD	ICGC;COSMIC	1.882	Down-regulation
CAMK_CAMK1_PNCK_ST	P07900	HSP90AA1	Q6P2M8	PNCK	S63	T65K	65	Missense	proximal	2	no	2.429	2.756	EPSD	ICGC	1.882	Up-regulation
CAMK_CAMK1_PNCK_ST	P07900	HSP90AA1	Q6P2M8	PNCK	S72	D66Y	66	Missense	distal	-6	no	2.146	2.199	EPSD	ICGC;COSMIC	1.882	Up-regulation
CAMK_CAMK1_PNCK_ST	P07900	HSP90AA1	Q6P2M8	PNCK	S72	I78V	78	Missense	distal	6	no	2.146	2.018	EPSD	ICGC;COSMIC	1.882	Down-regulation
CAMK_CAMK1_PNCK_ST	P07900	HSP90AA1	Q6P2M8	PNCK	S72	T65K	65	Missense	distal	-7	no	2.146	2.029	EPSD	ICGC	1.882	Down-regulation
CAMK_CAMK1_PNCK_ST	P07900	HSP90AA1	Q6P2M8	PNCK	S72	E75V	75	Missense	distal	3	no	2.146	2.647	EPSD	ICGC;COSMIC	1.882	Up-regulation
CAMK_CAMK1_PNCK_ST	P07900	HSP90AA1	Q6P2M8	PNCK	T94	G97E	97	Missense	distal	3	no	6.592	6.415	EPSD	ICGC;COSMIC	1.882	Down-regulation
CAMK_CAMK1_PNCK_ST	P07900	HSP90AA1	Q6P2M8	PNCK	T94	V92M	92	Missense	proximal	-2	no	6.592	6.488	EPSD	ICGC	1.882	Down-regulation
CAMK_CAMK1_PNCK_ST	P07900	HSP90AA1	Q6P2M8	PNCK	T94	G97R	97	Missense	distal	3	no	6.592	6.613	EPSD	ICGC;COSMIC	1.882	Up-regulation
CAMK_CAMK1_PNCK_ST	P07900	HSP90AA1	Q6P2M8	PNCK	T94	G95R	95	Missense	proximal	1	no	6.592	6.614	EPSD	ICGC;COSMIC	1.882	Up-regulation
CAMK_CAMK1_PNCK_ST	P07900	HSP90AA1	Q6P2M8	PNCK	T94	M98I	98	Missense	distal	4	no	6.592	6.674	EPSD	ICGC;COSMIC	1.882	Up-regulation
CAMK_CAMK1_PNCK_ST	P07900	HSP90AA1	Q6P2M8	PNCK	T94	L89P	89	Missense	distal	-5	no	6.592	6.364	EPSD	ICGC;COSMIC	1.882	Down-regulation
CAMK_CAMK1_PNCK_ST	P07900	HSP90AA1	Q6P2M8	PNCK	T94	T94N	94	Missense	central	0	yes	6.592	0.000	EPSD	ICGC;COSMIC	1.882	Loss
CAMK_CAMK1_PNCK_ST	P07900	HSP90AA1	Q6P2M8	PNCK	T99	G97E	97	Missense	proximal	-2	no	2.113	2.077	EPSD	ICGC;COSMIC	1.882	Down-regulation
CAMK_CAMK1_PNCK_ST	P07900	HSP90AA1	Q6P2M8	PNCK	T99	V92M	92	Missense	distal	-7	no	2.113	2.102	EPSD	ICGC	1.882	Down-regulation
CAMK_CAMK1_PNCK_ST	P07900	HSP90AA1	Q6P2M8	PNCK	T99	G97R	97	Missense	proximal	-2	no	2.113	2.074	EPSD	ICGC;COSMIC	1.882	Down-regulation
CAMK_CAMK1_PNCK_ST	P07900	HSP90AA1	Q6P2M8	PNCK	T99	G95R	95	Missense	distal	-4	no	2.113	2.024	EPSD	ICGC;COSMIC	1.882	Down-regulation
CAMK_CAMK1_PNCK_ST	P07900	HSP90AA1	Q6P2M8	PNCK	T99	M98I	98	Missense	proximal	-1	no	2.113	2.057	EPSD	ICGC;COSMIC	1.882	Down-regulation
CAMK_CAMK1_PNCK_ST	P07900	HSP90AA1	Q6P2M8	PNCK	T99	T94N	94	Missense	distal	-5	no	2.113	1.816	EPSD	ICGC;COSMIC	1.882	Loss
CAMK_CAMK1_PNCK_ST	P07900	HSP90AA1	Q6P2M8	PNCK	S129	S129F	129	Missense	central	0	yes	2.362	0.000	EPSD	ICGC;COSMIC	1.882	Loss
CAMK_CAMK1_PNCK_ST	P07900	HSP90AA1	Q6P2M8	PNCK	S129	G132R	132	Missense	distal	3	no	2.362	2.383	EPSD	ICGC;COSMIC	1.882	Up-regulation
CAMK_CAMK1_PNCK_ST	P07900	HSP90AA1	Q6P2M8	PNCK	S129	M130I	130	Missense	proximal	1	no	2.362	2.503	EPSD	ICGC;COSMIC	1.882	Up-regulation
CAMK_CAMK1_PNCK_ST	P07900	HSP90AA1	Q6P2M8	PNCK	S391	D390N	390	Missense	proximal	-1	no	7.125	6.883	PhosphoSitePlus;EPSD	ICGC;COSMIC	1.882	Down-regulation
CAMK_CAMK1_PNCK_ST	P07900	HSP90AA1	Q6P2M8	PNCK	S391	S391L	391	Missense	central	0	yes	7.125	0.000	PhosphoSitePlus;EPSD	ICGC;COSMIC	1.882	Loss
CAMK_CAMK1_PNCK_ST	P07900	HSP90AA1	Q6P2M8	PNCK	S391	G387W	387	Missense	distal	-4	no	7.125	6.875	PhosphoSitePlus;EPSD	ICGC;COSMIC	1.882	Down-regulation
CAMK_CAMK1_PNCK_ST	P07900	HSP90AA1	Q6P2M8	PNCK	S406	K410E	410	Missense	distal	4	no	2.418	2.271	EPSD	ICGC;COSMIC	1.882	Down-regulation
CAMK_CAMK1_PNCK_ST	P07900	HSP90AA1	Q6P2M8	PNCK	S406	Q405K	405	Missense	proximal	-1	no	2.418	2.120	EPSD	ICGC	1.882	Down-regulation
CAMK_CAMK1_PNCK_ST	P07900	HSP90AA1	Q6P2M8	PNCK	S406	S399T	399	Missense	distal	-7	no	2.418	2.476	EPSD	ICGC;COSMIC	1.882	Up-regulation
CAMK_CAMK1_PNCK_ST	P07900	HSP90AA1	Q6P2M8	PNCK	T498	D500N	500	Missense	proximal	2	no	1.636	1.897	EPSD	ICGC;COSMIC	1.882	Gain
CAMK_CAMK1_PNCK_ST	P07900	HSP90AA1	Q6P2M8	PNCK	S589	E584K	584	Missense	distal	-5	no	2.057	2.327	EPSD	ICGC;COSMIC	1.882	Up-regulation
CAMK_CAMK1_PNCK_ST	P07900	HSP90AA1	Q6P2M8	PNCK	S589	S595F	595	Missense	distal	6	no	2.057	2.255	EPSD	ICGC;COSMIC	1.882	Up-regulation
CAMK_CAMK1_PNCK_ST	P07900	HSP90AA1	Q6P2M8	PNCK	S595	V600I	600	Missense	distal	5	no	1.767	2.298	EPSD	ICGC;COSMIC	1.882	Gain
CAMK_CAMK1_PNCK_ST	P07900	HSP90AA1	Q6P2M8	PNCK	S602	I599V	599	Missense	distal	-3	no	1.253	1.947	EPSD	ICGC;COSMIC	1.882	Gain
CAMK_CAMK1_PNCK_ST	P07900	HSP90AA1	Q6P2M8	PNCK	T624	T624K	624	Missense	central	0	yes	7.043	0.000	EPSD;PhosphoSitePlus	ICGC	1.882	Loss
CAMK_CAMK1_PNCK_ST	P07900	HSP90AA1	Q6P2M8	PNCK	T624	A630E	630	Missense	distal	6	no	7.043	6.859	EPSD;PhosphoSitePlus	ICGC	1.882	Down-regulation
CAMK_CAMK1_PNCK_ST	P07900	HSP90AA1	Q6P2M8	PNCK	T624	M628V	628	Missense	distal	4	no	7.043	6.855	EPSD;PhosphoSitePlus	ICGC;COSMIC	1.882	Down-regulation
CAMK_CAMK1_PNCK_ST	P07900	HSP90AA1	Q6P2M8	PNCK	T708	A705D	705	Missense	distal	-3	no	1.283	2.026	EPSD	ICGC	1.882	Gain
CAMK_CAMK1_PNCK_ST	O43432	EIF4G3	Q6P2M8	PNCK	S351	L349Q	349	Missense	proximal	-2	no	2.106	1.948	EPSD	ICGC;COSMIC	1.882	Down-regulation
CAMK_CAMK1_PNCK_ST	O43432	EIF4G3	Q6P2M8	PNCK	S352	L349Q	349	Missense	distal	-3	no	2.762	2.457	EPSD	ICGC;COSMIC	1.882	Down-regulation
CAMK_PKD_PRKD2_ST	P50552	VASP	Q9BZL6	PRKD2	S157	A164S	164	Missense	distal	7	no	3.561	3.544	EPSD;PhosphoSitePlus	ICGC	1.791	Down-regulation
CAMK_PKD_PRKD2_ST	P50552	VASP	Q9BZL6	PRKD2	S157	V156F	156	Missense	proximal	-1	no	3.561	3.442	EPSD;PhosphoSitePlus	ICGC	1.791	Down-regulation
CAMK_PKD_PRKD2_ST	P50552	VASP	Q9BZL6	PRKD2	S157	I152M	152	Missense	distal	-5	no	3.561	3.251	EPSD;PhosphoSitePlus	ICGC;COSMIC	1.791	Down-regulation
CAMK_PKD_PRKD2_ST	P50552	VASP	Q9BZL6	PRKD2	S157	S157Y	157	Missense	central	0	yes	3.561	0.000	EPSD;PhosphoSitePlus	ICGC;COSMIC	1.791	Loss
CAMK_PKD_PRKD2_ST	P50552	VASP	Q9BZL6	PRKD2	S322	K321N	321	Missense	proximal	-1	no	3.733	3.693	EPSD;PhosphoSitePlus	ICGC	1.791	Down-regulation
CAMK_PKD_PRKD2_ST	P50552	VASP	Q9BZL6	PRKD2	S323	K321N	321	Missense	proximal	-2	no	1.795	1.748	EPSD	ICGC	1.791	Loss
CAMK_PKD_PRKD2_ST	P50552	VASP	Q9BZL6	PRKD2	S339	C334F	334	Missense	distal	-5	no	1.797	1.704	EPSD	ICGC	1.791	Loss
CAMK_PKD_PRKD2_ST	Q8WYL5	SSH1	Q9BZL6	PRKD2	S400	M395T	395	Missense	distal	-5	no	1.957	1.876	EPSD	ICGC;COSMIC	1.791	Down-regulation
CAMK_PKD_PRKD2_ST	Q8WYL5	SSH1	Q9BZL6	PRKD2	S400	I405M	405	Missense	distal	5	no	1.957	1.958	EPSD	ICGC;COSMIC	1.791	Up-regulation
CAMK_PKD_PRKD2_ST	Q8WYL5	SSH1	Q9BZL6	PRKD2	S400	T403K	403	Missense	distal	3	no	1.957	1.935	EPSD	ICGC	1.791	Down-regulation
CAMK_PKD_PRKD2_ST	Q8WYL5	SSH1	Q9BZL6	PRKD2	S400	A401V	401	Missense	proximal	1	no	1.957	1.904	EPSD	ICGC;COSMIC	1.791	Down-regulation
CAMK_PKD_PRKD2_ST	Q8WYL5	SSH1	Q9BZL6	PRKD2	S402	M395T	395	Missense	distal	-7	no	1.829	1.836	EPSD	ICGC;COSMIC	1.791	Up-regulation
CAMK_PKD_PRKD2_ST	Q8WYL5	SSH1	Q9BZL6	PRKD2	S402	I405M	405	Missense	distal	3	no	1.829	1.821	EPSD	ICGC;COSMIC	1.791	Down-regulation
CAMK_PKD_PRKD2_ST	Q8WYL5	SSH1	Q9BZL6	PRKD2	S402	A408E	408	Missense	distal	6	no	1.829	1.812	EPSD	ICGC	1.791	Down-regulation
CAMK_PKD_PRKD2_ST	Q8WYL5	SSH1	Q9BZL6	PRKD2	S402	T403K	403	Missense	proximal	1	no	1.829	1.801	EPSD	ICGC	1.791	Down-regulation
CAMK_PKD_PRKD2_ST	Q8WYL5	SSH1	Q9BZL6	PRKD2	S402	A401V	401	Missense	proximal	-1	no	1.829	1.839	EPSD	ICGC;COSMIC	1.791	Up-regulation
CAMK_PKD_PRKD2_ST	Q8WYL5	SSH1	Q9BZL6	PRKD2	S428	K424E	424	Missense	distal	-4	no	2.263	2.273	EPSD	ICGC	1.791	Up-regulation
CAMK_PKD_PRKD2_ST	Q8WYL5	SSH1	Q9BZL6	PRKD2	S428	R427L	427	Missense	proximal	-1	no	2.263	2.444	EPSD	ICGC;COSMIC	1.791	Up-regulation
CAMK_PKD_PRKD2_ST	Q8WYL5	SSH1	Q9BZL6	PRKD2	T462	R459C	459	Missense	distal	-3	no	2.221	1.373	EPSD	ICGC;COSMIC	1.791	Loss
CAMK_PKD_PRKD2_ST	Q8WYL5	SSH1	Q9BZL6	PRKD2	T462	D463E	463	Missense	proximal	1	no	2.221	2.219	EPSD	ICGC;COSMIC	1.791	Down-regulation
CAMK_PKD_PRKD2_ST	Q8WYL5	SSH1	Q9BZL6	PRKD2	T462	R459S	459	Missense	distal	-3	no	2.221	1.239	EPSD	ICGC	1.791	Loss
CAMK_PKD_PRKD2_ST	Q8WYL5	SSH1	Q9BZL6	PRKD2	T462	T462K	462	Missense	central	0	yes	2.221	0.000	EPSD	ICGC	1.791	Loss
CAMK_PKD_PRKD2_ST	Q8WYL5	SSH1	Q9BZL6	PRKD2	T462	K456N	456	Missense	distal	-6	no	2.221	2.231	EPSD	ICGC;COSMIC	1.791	Up-regulation
CAMK_PKD_PRKD2_ST	Q8WYL5	SSH1	Q9BZL6	PRKD2	S465	T462K	462	Missense	distal	-3	no	1.665	1.825	EPSD	ICGC	1.791	Gain
CAMK_PKD_PRKD2_ST	Q8WYL5	SSH1	Q9BZL6	PRKD2	S515	D516H	516	Missense	proximal	1	no	2.479	2.524	EPSD	ICGC;COSMIC	1.791	Up-regulation
CAMK_PKD_PRKD2_ST	Q8WYL5	SSH1	Q9BZL6	PRKD2	S528	L532V	532	Missense	distal	4	no	1.895	1.886	EPSD	ICGC;COSMIC	1.791	Down-regulation
CAMK_PKD_PRKD2_ST	Q8WYL5	SSH1	Q9BZL6	PRKD2	S528	H531Y	531	Missense	distal	3	no	1.895	1.899	EPSD	ICGC	1.791	Up-regulation
CAMK_PKD_PRKD2_ST	Q8WYL5	SSH1	Q9BZL6	PRKD2	S583	T590M	590	Missense	distal	7	no	2.440	2.439	EPSD	ICGC;COSMIC	1.791	Down-regulation
CAMK_PKD_PRKD2_ST	Q8WYL5	SSH1	Q9BZL6	PRKD2	S744	S739I	739	Missense	distal	-5	no	1.443	1.816	EPSD	ICGC;COSMIC	1.791	Gain
CAMK_PKD_PRKD2_ST	Q8WYL5	SSH1	Q9BZL6	PRKD2	S883	G878V	878	Missense	distal	-5	no	1.790	2.058	EPSD	ICGC;COSMIC	1.791	Gain
CAMK_PKD_PRKD2_ST	Q8WYL5	SSH1	Q9BZL6	PRKD2	S883	Q876K	876	Missense	distal	-7	no	1.790	1.826	EPSD	ICGC;COSMIC	1.791	Gain
CAMK_PKD_PRKD2_ST	Q8WYL5	SSH1	Q9BZL6	PRKD2	S883	A886T	886	Missense	distal	3	no	1.790	1.809	EPSD	ICGC;COSMIC	1.791	Gain
CAMK_PKD_PRKD2_ST	Q8WYL5	SSH1	Q9BZL6	PRKD2	S883	E884Q	884	Missense	proximal	1	no	1.790	1.880	EPSD	ICGC;COSMIC	1.791	Gain
CAMK_PKD_PRKD2_ST	Q8WYL5	SSH1	Q9BZL6	PRKD2	S937	S938R	938	Missense	proximal	1	no	4.154	3.770	EPSD;PhosphoSitePlus	ICGC	1.791	Down-regulation
CAMK_PKD_PRKD2_ST	Q8WYL5	SSH1	Q9BZL6	PRKD2	S937	H942N	942	Missense	distal	5	no	4.154	4.168	EPSD;PhosphoSitePlus	ICGC	1.791	Up-regulation
CAMK_PKD_PRKD2_ST	Q8WYL5	SSH1	Q9BZL6	PRKD2	S978	H977Y	977	Missense	proximal	-1	no	4.006	3.968	PhosphoSitePlus;EPSD	ICGC	1.791	Down-regulation
CAMK_PKD_PRKD2_ST	Q8WYL5	SSH1	Q9BZL6	PRKD2	S984	T986P	986	Missense	proximal	2	no	1.911	1.904	EPSD	ICGC	1.791	Down-regulation
CAMK_PKD_PRKD2_ST	Q8WYL5	SSH1	Q9BZL6	PRKD2	S984	D991E	991	Missense	distal	7	no	1.911	1.891	EPSD	ICGC;COSMIC	1.791	Down-regulation
CAMK_PKD_PRKD2_ST	Q8WYL5	SSH1	Q9BZL6	PRKD2	S984	T989K	989	Missense	distal	5	no	1.911	1.922	EPSD	ICGC;COSMIC	1.791	Up-regulation
CAMK_PKD_PRKD2_ST	Q8WYL5	SSH1	Q9BZL6	PRKD2	S984	H977Y	977	Missense	distal	-7	no	1.911	1.901	EPSD	ICGC	1.791	Down-regulation
CAMK_PKD_PRKD2_ST	Q8WYL5	SSH1	Q9BZL6	PRKD2	T989	T986P	986	Missense	distal	-3	no	1.881	1.627	EPSD	ICGC	1.791	Loss
CAMK_PKD_PRKD2_ST	Q8WYL5	SSH1	Q9BZL6	PRKD2	T989	D991E	991	Missense	proximal	2	no	1.881	1.877	EPSD	ICGC;COSMIC	1.791	Down-regulation
CAMK_PKD_PRKD2_ST	Q8WYL5	SSH1	Q9BZL6	PRKD2	T989	T989K	989	Missense	central	0	yes	1.881	0.000	EPSD	ICGC;COSMIC	1.791	Loss
CAMK_PKD_PRKD2_ST	Q13563	PKD2	Q9BZL6	PRKD2	S80	P77S	77	Missense	distal	-3	no	2.104	2.168	EPSD	ICGC	1.791	Up-regulation
CAMK_PKD_PRKD2_ST	Q13563	PKD2	Q9BZL6	PRKD2	S122	R123K	123	Missense	proximal	1	no	1.875	2.048	EPSD	ICGC;COSMIC	1.791	Up-regulation
CAMK_PKD_PRKD2_ST	Q13563	PKD2	Q9BZL6	PRKD2	S122	A127S	127	Missense	distal	5	no	1.875	1.883	EPSD	ICGC	1.791	Up-regulation
CAMK_PKD_PRKD2_ST	Q13563	PKD2	Q9BZL6	PRKD2	S801	S804I	804	Missense	distal	3	no	3.671	3.693	PhosphoSitePlus	ICGC	1.791	Up-regulation
CAMK_PKD_PRKD2_ST	Q7KZI7	MARK2	Q9BZL6	PRKD2	S29	S32F	32	Missense	distal	3	no	1.756	1.807	EPSD	ICGC;COSMIC	1.791	Gain
CAMK_PKD_PRKD2_ST	Q7KZI7	MARK2	Q9BZL6	PRKD2	S366	L359M	359	Missense	distal	-7	no	2.095	2.175	EPSD	ICGC;COSMIC	1.791	Up-regulation
CAMK_PKD_PRKD2_ST	Q7KZI7	MARK2	Q9BZL6	PRKD2	S400	R397H	397	Missense	distal	-3	no	3.643	2.490	PhosphoSitePlus	ICGC;COSMIC	1.791	Down-regulation
CAMK_PKD_PRKD2_ST	Q7KZI7	MARK2	Q9BZL6	PRKD2	S448	P454S	454	Missense	distal	6	no	2.138	2.291	EPSD	ICGC;COSMIC	1.791	Up-regulation
CAMK_PKD_PRKD2_ST	Q7KZI7	MARK2	Q9BZL6	PRKD2	S456	P454S	454	Missense	proximal	-2	no	1.770	1.856	EPSD	ICGC;COSMIC	1.791	Gain
CAMK_PKD_PRKD2_ST	Q7KZI7	MARK2	Q9BZL6	PRKD2	T466	L461F	461	Missense	distal	-5	no	2.131	1.540	EPSD	ICGC	1.791	Loss
CAMK_PKD_PRKD2_ST	Q7KZI7	MARK2	Q9BZL6	PRKD2	S648	R653L	653	Missense	distal	5	no	1.913	1.941	EPSD	ICGC;COSMIC	1.791	Up-regulation
CAMK_PKD_PRKD2_ST	Q7KZI7	MARK2	Q9BZL6	PRKD2	S648	R653W	653	Missense	distal	5	no	1.913	1.934	EPSD	ICGC;COSMIC	1.791	Up-regulation
CAMK_PKD_PRKD2_ST	Q9UBF8	PI4KB	Q9BZL6	PRKD2	S511	A515E	515	Missense	distal	4	no	2.376	2.477	EPSD	ICGC	1.791	Up-regulation
CAMK_PKD_PRKD2_ST	Q9BZL6	PRKD2	Q9BZL6	PRKD2	S206	G210V	210	Missense	distal	4	no	1.819	1.628	EPSD	ICGC;COSMIC	1.791	Loss
CAMK_PKD_PRKD2_ST	Q9BZL6	PRKD2	Q9BZL6	PRKD2	S529	A528E	528	Missense	proximal	-1	no	2.224	2.137	EPSD	ICGC	1.791	Down-regulation
CAMK_PKD_PRKD2_ST	P16144	ITGB4	Q9BZL6	PRKD2	S139	D144N	144	Missense	distal	5	no	2.381	2.399	EPSD	ICGC	1.791	Up-regulation
CAMK_PKD_PRKD2_ST	P16144	ITGB4	Q9BZL6	PRKD2	S139	S141F	141	Missense	proximal	2	no	2.381	2.359	EPSD	ICGC;COSMIC	1.791	Down-regulation
CAMK_PKD_PRKD2_ST	P16144	ITGB4	Q9BZL6	PRKD2	S139	F138S	138	Missense	proximal	-1	no	2.381	2.532	EPSD	ICGC;COSMIC	1.791	Up-regulation
CAMK_PKD_PRKD2_ST	P16144	ITGB4	Q9BZL6	PRKD2	T210	E215D	215	Missense	distal	5	no	1.994	1.973	EPSD	ICGC;COSMIC	1.791	Down-regulation
CAMK_PKD_PRKD2_ST	P16144	ITGB4	Q9BZL6	PRKD2	T210	R217W	217	Missense	distal	7	no	1.994	2.010	EPSD	ICGC	1.791	Up-regulation
CAMK_PKD_PRKD2_ST	P16144	ITGB4	Q9BZL6	PRKD2	S368	R367C	367	Missense	proximal	-1	no	2.612	2.663	EPSD	ICGC;COSMIC	1.791	Up-regulation
CAMK_PKD_PRKD2_ST	P16144	ITGB4	Q9BZL6	PRKD2	S368	R373L	373	Missense	distal	5	no	2.612	2.639	EPSD	ICGC	1.791	Up-regulation
CAMK_PKD_PRKD2_ST	P16144	ITGB4	Q9BZL6	PRKD2	T829	R826L	826	Missense	distal	-3	no	2.144	0.776	EPSD	ICGC	1.791	Loss
CAMK_PKD_PRKD2_ST	P16144	ITGB4	Q9BZL6	PRKD2	T829	R826H	826	Missense	distal	-3	no	2.144	0.991	EPSD	ICGC	1.791	Loss
CAMK_PKD_PRKD2_ST	P16144	ITGB4	Q9BZL6	PRKD2	T982	G975S	975	Missense	distal	-7	no	1.935	2.036	EPSD	ICGC	1.791	Up-regulation
CAMK_PKD_PRKD2_ST	P16144	ITGB4	Q9BZL6	PRKD2	S1000	E995G	995	Missense	distal	-5	no	1.571	1.804	EPSD	ICGC;COSMIC;GDSC	1.791	Gain
CAMK_PKD_PRKD2_ST	P16144	ITGB4	Q9BZL6	PRKD2	S1069	R1074H	1074	Missense	distal	5	no	1.956	1.973	EPSD	ICGC;COSMIC	1.791	Up-regulation
CAMK_PKD_PRKD2_ST	P16144	ITGB4	Q9BZL6	PRKD2	S1069	V1067A	1067	Missense	proximal	-2	no	1.956	2.009	EPSD	ICGC	1.791	Up-regulation
CAMK_PKD_PRKD2_ST	P16144	ITGB4	Q9BZL6	PRKD2	S1069	G1073V	1073	Missense	distal	4	no	1.956	1.765	EPSD	ICGC	1.791	Loss
CAMK_PKD_PRKD2_ST	P16144	ITGB4	Q9BZL6	PRKD2	S1069	R1074C	1074	Missense	distal	5	no	1.956	1.987	EPSD	ICGC;GDSC;CCLE	1.791	Up-regulation
CAMK_PKD_PRKD2_ST	P16144	ITGB4	Q9BZL6	PRKD2	S1069	L1070I	1070	Missense	proximal	1	no	1.956	1.933	EPSD	ICGC;COSMIC	1.791	Down-regulation
CAMK_PKD_PRKD2_ST	P16144	ITGB4	Q9BZL6	PRKD2	S1084	S1084N	1084	Missense	central	0	yes	2.192	0.000	EPSD	ICGC;COSMIC	1.791	Loss
CAMK_PKD_PRKD2_ST	P16144	ITGB4	Q9BZL6	PRKD2	S1084	V1081F	1081	Missense	distal	-3	no	2.192	2.136	EPSD	ICGC	1.791	Down-regulation
CAMK_PKD_PRKD2_ST	P16144	ITGB4	Q9BZL6	PRKD2	S1084	A1090S	1090	Missense	distal	6	no	2.192	2.286	EPSD	ICGC	1.791	Up-regulation
CAMK_PKD_PRKD2_ST	P16144	ITGB4	Q9BZL6	PRKD2	S1084	R1078C	1078	Missense	distal	-6	no	2.192	2.183	EPSD	ICGC;COSMIC	1.791	Down-regulation
CAMK_PKD_PRKD2_ST	P16144	ITGB4	Q9BZL6	PRKD2	S1118	P1121S	1121	Missense	distal	3	no	2.001	1.977	EPSD	ICGC	1.791	Down-regulation
CAMK_PKD_PRKD2_ST	P16144	ITGB4	Q9BZL6	PRKD2	S1119	P1121S	1121	Missense	proximal	2	no	1.925	1.939	EPSD	ICGC	1.791	Up-regulation
CAMK_PKD_PRKD2_ST	P16144	ITGB4	Q9BZL6	PRKD2	S1325	P1320L	1320	Missense	distal	-5	no	1.790	2.579	EPSD	ICGC;COSMIC	1.791	Gain
CAMK_PKD_PRKD2_ST	P16144	ITGB4	Q9BZL6	PRKD2	S1345	S1350I	1350	Missense	distal	5	no	1.897	1.884	EPSD	ICGC	1.791	Down-regulation
CAMK_PKD_PRKD2_ST	P16144	ITGB4	Q9BZL6	PRKD2	S1428	S1428L	1428	Missense	central	0	yes	1.888	0.000	EPSD	ICGC;COSMIC	1.791	Loss
CAMK_PKD_PRKD2_ST	P16144	ITGB4	Q9BZL6	PRKD2	T1434	S1428L	1428	Missense	distal	-6	no	2.194	2.222	EPSD	ICGC;COSMIC	1.791	Up-regulation
CAMK_PKD_PRKD2_ST	P16144	ITGB4	Q9BZL6	PRKD2	T1721	P1726L	1726	Missense	distal	5	no	2.114	2.110	EPSD	ICGC	1.791	Down-regulation
CAMK_PKD_PRKD2_ST	P16144	ITGB4	Q9BZL6	PRKD2	S1791	T1793A	1793	Missense	proximal	2	no	1.912	1.916	EPSD	ICGC;COSMIC	1.791	Up-regulation
CAMK_PKD_PRKD2_ST	P16144	ITGB4	Q9BZL6	PRKD2	T1797	T1793A	1793	Missense	distal	-4	no	2.609	2.603	EPSD	ICGC;COSMIC	1.791	Down-regulation
CAMK_PKD_PRKD2_ST	Q13671	RIN1	Q9BZL6	PRKD2	S255	S250Y	250	Missense	distal	-5	no	2.005	2.024	EPSD	ICGC;COSMIC	1.791	Up-regulation
CAMK_PKD_PRKD2_ST	Q13671	RIN1	Q9BZL6	PRKD2	S255	P259T	259	Missense	distal	4	no	2.005	1.843	EPSD	ICGC;COSMIC	1.791	Down-regulation
CAMK_PKD_PRKD2_ST	Q13671	RIN1	Q9BZL6	PRKD2	S255	A261V	261	Missense	distal	6	no	2.005	1.944	EPSD	ICGC	1.791	Down-regulation
CAMK_PKD_PRKD2_ST	Q13671	RIN1	Q9BZL6	PRKD2	S337	P338T	338	Missense	proximal	1	no	1.969	2.154	EPSD	ICGC;COSMIC	1.791	Up-regulation
CAMK_PKD_PRKD2_ST	Q13671	RIN1	Q9BZL6	PRKD2	S351	A352T	352	Missense	proximal	1	no	2.587	2.507	EPSD	ICGC;COSMIC	1.791	Down-regulation
CAMK_PKD_PRKD2_ST	Q13671	RIN1	Q9BZL6	PRKD2	S351	S351N	351	Missense	central	0	yes	2.587	0.000	EPSD	ICGC;COSMIC	1.791	Loss
CAMK_PKD_PRKD2_ST	Q99828	CIB1	Q9BZL6	PRKD2	S78	D84Y	84	Missense	distal	6	no	3.471	3.450	PhosphoSitePlus	ICGC	1.791	Down-regulation
CAMK_CAMK2_CAMK2B_ST	Q13131	PRKAA1	Q13554	CAMK2B	S486	E480K	480	Missense	distal	-6	no	137.013	137.625	EPSD	ICGC;COSMIC	127.946	Up-regulation
CAMK_CAMK2_CAMK2B_ST	Q13131	PRKAA1	Q13554	CAMK2B	S486	D479A	479	Missense	distal	-7	no	137.013	137.525	EPSD	ICGC	127.946	Up-regulation
CAMK_CAMK2_CAMK2B_ST	Q13131	PRKAA1	Q13554	CAMK2B	S496	S498C	498	Missense	proximal	2	no	151.709	149.563	EPSD	ICGC;COSMIC	127.946	Down-regulation
CAMK_CAMK2_CAMK2B_ST	Q13131	PRKAA1	Q13554	CAMK2B	S496	R501P	501	Missense	distal	5	no	151.709	152.077	EPSD	ICGC;COSMIC	127.946	Up-regulation
CAMK_CAMK2_CAMK2B_ST	Q13131	PRKAA1	Q13554	CAMK2B	S496	C503Y	503	Missense	distal	7	no	151.709	150.466	EPSD	ICGC	127.946	Down-regulation
CAMK_CAMK2_CAMK2B_ST	Q13131	PRKAA1	Q13554	CAMK2B	S496	Y500C	500	Missense	distal	4	no	151.709	150.385	EPSD	ICGC;COSMIC	127.946	Down-regulation
CAMK_CAMK2_CAMK2B_ST	Q13131	PRKAA1	Q13554	CAMK2B	S508	C503Y	503	Missense	distal	-5	no	123.371	134.142	EPSD	ICGC	127.946	Gain
CAMK_CAMK2_CAMK2B_ST	Q13555	CAMK2G	Q13554	CAMK2B	S36	A41T	41	Missense	distal	5	no	138.642	137.419	EPSD	ICGC;COSMIC;GDSC;CCLE	127.946	Down-regulation
CAMK_CAMK2_CAMK2B_ST	Q13555	CAMK2G	Q13554	CAMK2B	T254	P257T	257	Missense	distal	3	no	144.247	145.871	EPSD	ICGC	127.946	Up-regulation
CAMK_CAMK2_CAMK2B_ST	Q13555	CAMK2G	Q13554	CAMK2B	T254	Q251K	251	Missense	distal	-3	no	144.247	156.300	EPSD	ICGC;COSMIC	127.946	Up-regulation
CAMK_CAMK2_CAMK2B_ST	Q13555	CAMK2G	Q13554	CAMK2B	S280	T277M	277	Missense	distal	-3	no	132.658	131.520	EPSD	ICGC;COSMIC	127.946	Down-regulation
CAMK_CAMK2_CAMK2B_ST	Q13555	CAMK2G	Q13554	CAMK2B	T307	F314C	314	Missense	distal	7	no	160.341	160.283	EPSD	ICGC	127.946	Down-regulation
CAMK_CAMK2_CAMK2B_ST	Q13555	CAMK2G	Q13554	CAMK2B	S315	F314C	314	Missense	proximal	-1	no	158.111	153.235	EPSD	ICGC	127.946	Down-regulation
CAMK_CAMK2_CAMK2B_ST	Q13555	CAMK2G	Q13554	CAMK2B	S319	F314C	314	Missense	distal	-5	no	148.629	141.572	EPSD	ICGC	127.946	Down-regulation
CAMK_CAMK2_CAMK2B_ST	Q13555	CAMK2G	Q13554	CAMK2B	S335	H339R	339	Missense	distal	4	no	176.809	177.377	EPSD	ICGC;COSMIC	127.946	Up-regulation
CAMK_CAMK2_CAMK2B_ST	Q13555	CAMK2G	Q13554	CAMK2B	S335	K333E	333	Missense	proximal	-2	no	176.809	176.429	EPSD	ICGC	127.946	Down-regulation
CAMK_CAMK2_CAMK2B_ST	Q13555	CAMK2G	Q13554	CAMK2B	S337	H339R	339	Missense	proximal	2	no	154.684	157.623	EPSD	ICGC;COSMIC	127.946	Up-regulation
CAMK_CAMK2_CAMK2B_ST	Q13555	CAMK2G	Q13554	CAMK2B	S337	K333E	333	Missense	distal	-4	no	154.684	149.741	EPSD	ICGC	127.946	Down-regulation
CAMK_CAMK2_CAMK2B_ST	P16949	STMN1	Q13554	CAMK2B	S63	S63F	63	Missense	central	0	yes	130.393	0.000	EPSD	ICGC;COSMIC	127.946	Loss
CAMK_CAMK2_CAMK2B_ST	P16949	STMN1	Q13554	CAMK2B	T102	A97E	97	Missense	distal	-5	no	165.852	159.432	EPSD	ICGC	127.946	Down-regulation
CAMK_CAMK2_CAMK2B_ST	P16949	STMN1	Q13554	CAMK2B	T102	H103N	103	Missense	proximal	1	no	165.852	156.789	EPSD	ICGC	127.946	Down-regulation
STE_STE20_PAKB_PAK5_ST	P15976	GATA1	Q9P286	PAK5	S107	P105T	105	Missense	proximal	-2	no	4.412	4.279	EPSD	ICGC;COSMIC	3.202	Down-regulation
STE_STE20_PAKB_PAK5_ST	P15976	GATA1	Q9P286	PAK5	S161	S155L	155	Missense	distal	-6	no	7.382	7.614	PhosphoSitePlus;EPSD	ICGC;COSMIC	3.202	Up-regulation
STE_STE20_PAKB_PAK5_ST	P15976	GATA1	Q9P286	PAK5	S161	G165S	165	Missense	distal	4	no	7.382	7.191	PhosphoSitePlus;EPSD	ICGC;COSMIC	3.202	Down-regulation
STE_STE20_PAKB_PAK5_ST	P15976	GATA1	Q9P286	PAK5	S161	P159H	159	Missense	proximal	-2	no	7.382	7.312	PhosphoSitePlus;EPSD	ICGC;COSMIC	3.202	Down-regulation
STE_STE20_PAKB_PAK5_ST	P15976	GATA1	Q9P286	PAK5	S161	V158F	158	Missense	distal	-3	no	7.382	7.383	PhosphoSitePlus;EPSD	ICGC;COSMIC	3.202	Up-regulation
STE_STE20_PAKB_PAK5_ST	P15976	GATA1	Q9P286	PAK5	S161	G164V	164	Missense	distal	3	no	7.382	7.337	PhosphoSitePlus;EPSD	ICGC;COSMIC	3.202	Down-regulation
STE_STE20_PAKB_PAK5_ST	P15976	GATA1	Q9P286	PAK5	S161	P166T	166	Missense	distal	5	no	7.382	7.367	PhosphoSitePlus;EPSD	ICGC;COSMIC	3.202	Down-regulation
STE_STE20_PAKB_PAK5_ST	P15976	GATA1	Q9P286	PAK5	S187	L194F	194	Missense	distal	7	no	7.306	7.581	EPSD;PhosphoSitePlus	ICGC	3.202	Up-regulation
STE_STE20_PAKB_PAK5_ST	P15976	GATA1	Q9P286	PAK5	T304	R298Q	298	Missense	distal	-6	no	3.260	3.477	EPSD	ICGC;COSMIC	3.202	Up-regulation
STE_STE20_PAKB_PAK5_ST	P15976	GATA1	Q9P286	PAK5	T304	Q303K	303	Missense	proximal	-1	no	3.260	3.383	EPSD	ICGC;COSMIC	3.202	Up-regulation
STE_STE20_PAKB_PAK5_ST	P15976	GATA1	Q9P286	PAK5	T304	R307S	307	Missense	distal	3	no	3.260	3.302	EPSD	ICGC;COSMIC	3.202	Up-regulation
STE_STE20_PAKB_PAK5_ST	P15976	GATA1	Q9P286	PAK5	T304	R298L	298	Missense	distal	-6	no	3.260	3.264	EPSD	ICGC;COSMIC	3.202	Up-regulation
STE_STE20_PAKB_PAK5_ST	P15923	TCF3	Q9P286	PAK5	S39	A41T	41	Missense	proximal	2	no	8.243	8.237	PhosphoSitePlus	ICGC;COSMIC	3.202	Down-regulation
STE_STE20_PAKB_PAK5_ST	P15923	TCF3	Q9P286	PAK5	S39	G46A	46	Missense	distal	7	no	8.243	8.194	PhosphoSitePlus	ICGC	3.202	Down-regulation
STE_STE20_PAKB_PAK5_ST	P15923	TCF3	Q9P286	PAK5	S55	P54S	54	Missense	proximal	-1	no	4.552	5.067	EPSD	ICGC	3.202	Up-regulation
STE_STE20_PAKB_PAK5_ST	P15923	TCF3	Q9P286	PAK5	S110	G112W	112	Missense	proximal	2	no	4.236	4.225	EPSD	ICGC;COSMIC	3.202	Down-regulation
STE_STE20_PAKB_PAK5_ST	P15923	TCF3	Q9P286	PAK5	S110	Y108H	108	Missense	proximal	-2	no	4.236	4.279	EPSD	ICGC;COSMIC	3.202	Up-regulation
STE_STE20_PAKB_PAK5_ST	P15923	TCF3	Q9P286	PAK5	S110	G103C	103	Missense	distal	-7	no	4.236	4.390	EPSD	ICGC;COSMIC	3.202	Up-regulation
STE_STE20_PAKB_PAK5_ST	P15923	TCF3	Q9P286	PAK5	S157	R159Q	159	Missense	proximal	2	no	3.421	3.465	EPSD	ICGC;COSMIC	3.202	Up-regulation
STE_STE20_PAKB_PAK5_ST	P15923	TCF3	Q9P286	PAK5	S157	A162E	162	Missense	distal	5	no	3.421	3.428	EPSD	ICGC	3.202	Up-regulation
STE_STE20_PAKB_PAK5_ST	P15923	TCF3	Q9P286	PAK5	S306	G302C	302	Missense	distal	-4	no	4.206	4.096	EPSD	ICGC;COSMIC	3.202	Down-regulation
STE_STE20_PAKB_PAK5_ST	P15923	TCF3	Q9P286	PAK5	S306	G303S	303	Missense	distal	-3	no	4.206	4.208	EPSD	ICGC;COSMIC;CCLE	3.202	Up-regulation
STE_STE20_PAKB_PAK5_ST	P15923	TCF3	Q9P286	PAK5	S352	S359C	359	Missense	distal	7	no	3.389	3.710	EPSD	ICGC	3.202	Up-regulation
STE_STE20_PAKB_PAK5_ST	P15923	TCF3	Q9P286	PAK5	S352	S359F	359	Missense	distal	7	no	3.389	3.918	EPSD	ICGC;COSMIC	3.202	Up-regulation
STE_STE20_PAKB_PAK5_ST	P15923	TCF3	Q9P286	PAK5	T508	E515K	515	Missense	distal	7	no	3.168	3.271	EPSD	ICGC	3.202	Gain
CAMK_CASK_CASK_ST	O14936	CASK	O14936	CASK	S51	T49K	49	Missense	proximal	-2	no	3.339	3.355	EPSD	ICGC	2.569	Up-regulation
CAMK_CASK_CASK_ST	O14936	CASK	O14936	CASK	S51	G53V	53	Missense	proximal	2	no	3.339	3.350	EPSD	ICGC;COSMIC	2.569	Up-regulation
CAMK_CASK_CASK_ST	O14936	CASK	O14936	CASK	S51	T56I	56	Missense	distal	5	no	3.339	3.279	EPSD	ICGC;COSMIC	2.569	Down-regulation
CAMK_CASK_CASK_ST	O14936	CASK	O14936	CASK	S151	V147G	147	Missense	distal	-4	no	7.373	7.376	PhosphoSitePlus;EPSD	ICGC	2.569	Up-regulation
CAMK_CASK_CASK_ST	O14936	CASK	O14936	CASK	S313	A310G	310	Missense	distal	-3	no	2.590	2.532	EPSD	ICGC	2.569	Loss
CAMK_CASK_CASK_ST	O14936	CASK	O14936	CASK	S394	T392K	392	Missense	proximal	-2	no	2.904	2.921	EPSD	ICGC	2.569	Up-regulation
CAMK_CASK_CASK_ST	O14936	CASK	O14936	CASK	S394	P396Q	396	Missense	proximal	2	no	2.904	2.957	EPSD	ICGC;COSMIC	2.569	Up-regulation
CAMK_CASK_CASK_ST	O14936	CASK	O14936	CASK	S394	R399G	399	Missense	distal	5	no	2.904	2.928	EPSD	ICGC;COSMIC	2.569	Up-regulation
CAMK_CASK_CASK_ST	O14936	CASK	O14936	CASK	S395	T392K	392	Missense	distal	-3	no	2.118	3.664	EPSD	ICGC	2.569	Gain
CAMK_CASK_CASK_ST	O14936	CASK	O14936	CASK	S562	R560W	560	Missense	proximal	-2	no	3.665	3.645	EPSD	ICGC;COSMIC	2.569	Down-regulation
CAMK_CASK_CASK_ST	O14936	CASK	O14936	CASK	S562	G561W	561	Missense	proximal	-1	no	3.665	3.668	EPSD	ICGC;COSMIC	2.569	Up-regulation
CAMK_CASK_CASK_ST	O14936	CASK	O14936	CASK	S562	R560L	560	Missense	proximal	-2	no	3.665	3.652	EPSD	ICGC;COSMIC	2.569	Down-regulation
CAMK_CASK_CASK_ST	O14936	CASK	O14936	CASK	S562	R557M	557	Missense	distal	-5	no	3.665	3.733	EPSD	ICGC;COSMIC	2.569	Up-regulation
CAMK_CASK_CASK_ST	O14936	CASK	O14936	CASK	S596	G593C	593	Missense	distal	-3	no	2.754	2.844	EPSD	ICGC;COSMIC	2.569	Up-regulation
TK_FGFR_FGFR3_Y	P51812	RPS6KA3	P22607	FGFR3	Y226	Y226N	226	Missense	central	0	yes	0.000	0.000	EPSD	ICGC;COSMIC	0.000	Loss
TK_FGFR_FGFR3_Y	P51812	RPS6KA3	P22607	FGFR3	Y422	Y422C	422	Missense	central	0	yes	0.000	0.000	EPSD	ICGC;COSMIC	0.000	Loss
TK_FGFR_FGFR3_Y	P51812	RPS6KA3	P22607	FGFR3	Y529	Y529C	529	Missense	central	0	yes	0.000	0.000	PhosphoSitePlus;EPSD	ICGC;COSMIC	0.000	Loss
TK_FGFR_FGFR3_Y	P60484	PTEN	P22607	FGFR3	Y27	Y27N	27	Missense	central	0	yes	0.000	0.000	EPSD	ICGC;COSMIC	0.000	Loss
TK_FGFR_FGFR3_Y	P60484	PTEN	P22607	FGFR3	Y46	Y46D	46	Missense	central	0	yes	0.000	0.000	EPSD	ICGC;COSMIC	0.000	Loss
TK_FGFR_FGFR3_Y	P60484	PTEN	P22607	FGFR3	Y68	Y68N	68	Missense	central	0	yes	0.000	0.000	EPSD	ICGC;COSMIC	0.000	Loss
TK_FGFR_FGFR3_Y	P60484	PTEN	P22607	FGFR3	Y68	Y68H	68	Missense	central	0	yes	0.000	0.000	EPSD	ICGC;COSMIC;GDSC;CCLE	0.000	Loss
TK_FGFR_FGFR3_Y	P60484	PTEN	P22607	FGFR3	Y138	Y138D	138	Missense	central	0	yes	0.000	0.000	EPSD	ICGC;COSMIC	0.000	Loss
TK_FGFR_FGFR3_Y	P60484	PTEN	P22607	FGFR3	Y138	Y138S	138	Missense	central	0	yes	0.000	0.000	EPSD	ICGC;COSMIC	0.000	Loss
TK_FGFR_FGFR3_Y	P60484	PTEN	P22607	FGFR3	Y138	Y138C	138	Missense	central	0	yes	0.000	0.000	EPSD	ICGC;COSMIC;GDSC;CCLE	0.000	Loss
TK_FGFR_FGFR3_Y	P60484	PTEN	P22607	FGFR3	Y177	Y177C	177	Missense	central	0	yes	0.000	0.000	EPSD	ICGC;COSMIC	0.000	Loss
TK_FGFR_FGFR3_Y	P60484	PTEN	P22607	FGFR3	Y177	Y177S	177	Missense	central	0	yes	0.000	0.000	EPSD	ICGC;COSMIC	0.000	Loss
TK_FGFR_FGFR3_Y	P60484	PTEN	P22607	FGFR3	Y178	Y178S	178	Missense	central	0	yes	0.000	0.000	EPSD	ICGC;COSMIC	0.000	Loss
STE_STE7_MEK3_MAP2K6_ST	P52564	MAP2K6	P52564	MAP2K6	S35	D32V	32	Missense	distal	-3	no	2.336	2.095	EPSD	ICGC;COSMIC	1.858	Down-regulation
STE_STE7_MEK3_MAP2K6_ST	P52564	MAP2K6	P52564	MAP2K6	S35	D32Y	32	Missense	distal	-3	no	2.336	2.233	EPSD	ICGC	1.858	Down-regulation
STE_STE7_MEK3_MAP2K6_ST	Q16539	MAPK14	P52564	MAP2K6	T7	P6A	6	Missense	proximal	-1	no	3.567	3.603	EPSD	ICGC;GDSC	1.858	Up-regulation
STE_STE7_MEK3_MAP2K6_ST	Q16539	MAPK14	P52564	MAP2K6	T123	D125Y	125	Missense	proximal	2	no	-0.778	2.481	EPSD	ICGC	1.858	Gain
STE_STE7_MEK3_MAP2K6_ST	Q9NQU5	PAK6	P52564	MAP2K6	T326	L333F	333	Missense	distal	7	no	3.364	3.371	EPSD	ICGC;COSMIC	1.858	Up-regulation
TK_Csk_MATK_Y	P78324	SIRPA	P42679	MATK	Y453	T451M	451	Missense	proximal	-2	no	5.088	5.082	PhosphoSitePlus;EPSD	ICGC;COSMIC;GDSC;CCLE	1.382	Down-regulation
TK_Csk_MATK_Y	P78324	SIRPA	P42679	MATK	Y453	S459I	459	Missense	distal	6	no	5.088	5.091	PhosphoSitePlus;EPSD	ICGC;COSMIC	1.382	Up-regulation
TK_Csk_MATK_Y	P78324	SIRPA	P42679	MATK	Y453	T458S	458	Missense	distal	5	no	5.088	5.069	PhosphoSitePlus;EPSD	ICGC;COSMIC	1.382	Down-regulation
TK_Csk_MATK_Y	P78324	SIRPA	P42679	MATK	Y453	S455N	455	Missense	proximal	2	no	5.088	4.996	PhosphoSitePlus;EPSD	ICGC	1.382	Down-regulation
TK_Csk_MATK_Y	P07948	LYN	P42679	MATK	Y508	A503D	503	Missense	distal	-5	no	4.938	4.952	PhosphoSitePlus	ICGC;COSMIC	1.382	Up-regulation
CK1_VRK_VRK2_ST	P38432	COIL	Q86Y07	VRK2	T169	N166S	166	Missense	distal	-3	no	48.054	48.984	EPSD	ICGC;COSMIC	34.967	Up-regulation
CK1_VRK_VRK2_ST	P38432	COIL	Q86Y07	VRK2	T169	R164I	164	Missense	distal	-5	no	48.054	46.799	EPSD	ICGC;COSMIC;GDSC;CCLE	34.967	Down-regulation
CK1_VRK_VRK2_ST	P38432	COIL	Q86Y07	VRK2	T172	E178K	178	Missense	distal	6	no	38.608	46.698	EPSD	ICGC;COSMIC	34.967	Up-regulation
CK1_VRK_VRK2_ST	P38432	COIL	Q86Y07	VRK2	T172	N177K	177	Missense	distal	5	no	38.608	36.785	EPSD	ICGC	34.967	Down-regulation
CK1_VRK_VRK2_ST	P38432	COIL	Q86Y07	VRK2	T172	N166S	166	Missense	distal	-6	no	38.608	38.876	EPSD	ICGC;COSMIC	34.967	Up-regulation
CK1_VRK_VRK2_ST	P38432	COIL	Q86Y07	VRK2	T172	E179A	179	Missense	distal	7	no	38.608	38.855	EPSD	ICGC	34.967	Up-regulation
CK1_VRK_VRK2_ST	P38432	COIL	Q86Y07	VRK2	S184	E178K	178	Missense	distal	-6	no	100.519	100.586	PhosphoSitePlus	ICGC;COSMIC	34.967	Up-regulation
CK1_VRK_VRK2_ST	P38432	COIL	Q86Y07	VRK2	S184	N177K	177	Missense	distal	-7	no	100.519	96.072	PhosphoSitePlus	ICGC	34.967	Down-regulation
CK1_VRK_VRK2_ST	P38432	COIL	Q86Y07	VRK2	S184	A180D	180	Missense	distal	-4	no	100.519	100.877	PhosphoSitePlus	ICGC	34.967	Up-regulation
CK1_VRK_VRK2_ST	P38432	COIL	Q86Y07	VRK2	S184	E179A	179	Missense	distal	-5	no	100.519	102.094	PhosphoSitePlus	ICGC	34.967	Up-regulation
CK1_VRK_VRK2_ST	P38432	COIL	Q86Y07	VRK2	S184	K181E	181	Missense	distal	-3	no	100.519	103.832	PhosphoSitePlus	ICGC;COSMIC	34.967	Up-regulation
CK1_VRK_VRK2_ST	P38432	COIL	Q86Y07	VRK2	S217	D210E	210	Missense	distal	-7	no	36.934	37.985	EPSD	ICGC;COSMIC	34.967	Up-regulation
CK1_VRK_VRK2_ST	P38432	COIL	Q86Y07	VRK2	S235	V236I	236	Missense	proximal	1	no	34.699	36.167	EPSD	ICGC;COSMIC	34.967	Gain
CK1_VRK_VRK2_ST	P38432	COIL	Q86Y07	VRK2	S237	V236I	236	Missense	proximal	-1	no	35.455	35.857	EPSD	ICGC;COSMIC	34.967	Up-regulation
CK1_VRK_VRK2_ST	Q96EV8	DTNBP1	Q86Y07	VRK2	S53	S53R	53	Missense	central	0	yes	44.147	0.000	EPSD	ICGC	34.967	Loss
CK1_VRK_VRK2_ST	Q96EV8	DTNBP1	Q86Y07	VRK2	S53	G48E	48	Missense	distal	-5	no	44.147	39.872	EPSD	ICGC	34.967	Down-regulation
CK1_VRK_VRK2_ST	Q96EV8	DTNBP1	Q86Y07	VRK2	S124	N130K	130	Missense	distal	6	no	31.330	42.286	EPSD	ICGC	34.967	Gain
AGC_DMPK_ROCK_ROCK1_ST	Q14160	SCRIB	Q13464	ROCK1	S372	L370R	370	Missense	proximal	-2	no	28.675	42.266	EPSD	ICGC	31.796	Gain
AGC_DMPK_ROCK_ROCK1_ST	Q14160	SCRIB	Q13464	ROCK1	T475	R468Q	468	Missense	distal	-7	no	48.836	48.753	EPSD	ICGC;COSMIC	31.796	Down-regulation
AGC_DMPK_ROCK_ROCK1_ST	Q14160	SCRIB	Q13464	ROCK1	T475	R473Q	473	Missense	proximal	-2	no	48.836	35.666	EPSD	ICGC;COSMIC	31.796	Down-regulation
AGC_DMPK_ROCK_ROCK1_ST	Q14160	SCRIB	Q13464	ROCK1	T607	I603N	603	Missense	distal	-4	no	46.730	46.936	EPSD	ICGC;COSMIC	31.796	Up-regulation
AGC_DMPK_ROCK_ROCK1_ST	Q14160	SCRIB	Q13464	ROCK1	T883	G879V	879	Missense	distal	-4	no	32.465	31.627	EPSD	ICGC;COSMIC	31.796	Loss
AGC_DMPK_ROCK_ROCK1_ST	Q14160	SCRIB	Q13464	ROCK1	T1130	E1132K	1132	Missense	proximal	2	no	32.335	36.005	EPSD	ICGC	31.796	Up-regulation
AGC_DMPK_ROCK_ROCK1_ST	Q14160	SCRIB	Q13464	ROCK1	S1378	P1374F	1374	Missense	distal	-4	no	39.728	39.079	EPSD;PhosphoSitePlus	ICGC	31.796	Down-regulation
AGC_DMPK_ROCK_ROCK1_ST	Q14160	SCRIB	Q13464	ROCK1	S1508	R1502G	1502	Missense	distal	-6	no	38.412	37.346	PhosphoSitePlus;EPSD	ICGC	31.796	Down-regulation
AGC_DMPK_ROCK_ROCK1_ST	Q14160	SCRIB	Q13464	ROCK1	S1566	P1562A	1562	Missense	distal	-4	no	30.755	31.978	EPSD	ICGC;COSMIC	31.796	Gain
AGC_DMPK_ROCK_ROCK1_ST	P35241	RDX	Q13464	ROCK1	T66	Q67K	67	Missense	proximal	1	no	36.036	35.602	EPSD	ICGC;COSMIC	31.796	Down-regulation
AGC_DMPK_ROCK_ROCK1_ST	P35241	RDX	Q13464	ROCK1	T66	K64N	64	Missense	proximal	-2	no	36.036	33.498	EPSD	ICGC;COSMIC	31.796	Down-regulation
AGC_DMPK_ROCK_ROCK1_ST	P35241	RDX	Q13464	ROCK1	T564	A557E	557	Missense	distal	-7	no	33.014	33.035	PhosphoSitePlus	ICGC	31.796	Up-regulation
AGC_DMPK_ROCK_ROCK1_ST	P61587	RND3	Q13464	ROCK1	S7	S14Y	14	Missense	distal	7	no	40.635	40.462	EPSD;PhosphoSitePlus	ICGC	31.796	Down-regulation
AGC_DMPK_ROCK_ROCK1_ST	P61587	RND3	Q13464	ROCK1	S7	Q8K	8	Missense	proximal	1	no	40.635	40.201	EPSD;PhosphoSitePlus	ICGC	31.796	Down-regulation
AGC_DMPK_ROCK_ROCK1_ST	P61587	RND3	Q13464	ROCK1	S7	E3K	3	Missense	distal	-4	no	40.635	44.302	EPSD;PhosphoSitePlus	ICGC;COSMIC	31.796	Up-regulation
AGC_DMPK_ROCK_ROCK1_ST	P61587	RND3	Q13464	ROCK1	S7	L10M	10	Missense	distal	3	no	40.635	40.757	EPSD;PhosphoSitePlus	ICGC;COSMIC	31.796	Up-regulation
AGC_DMPK_ROCK_ROCK1_ST	P61587	RND3	Q13464	ROCK1	S11	Q8K	8	Missense	distal	-3	no	30.668	31.840	EPSD;PhosphoSitePlus	ICGC	31.796	Gain
AGC_DMPK_ROCK_ROCK1_ST	P61587	RND3	Q13464	ROCK1	S11	L10M	10	Missense	proximal	-1	no	30.668	32.380	EPSD;PhosphoSitePlus	ICGC;COSMIC	31.796	Gain
AGC_DMPK_ROCK_ROCK1_ST	P19634	SLC9A1	Q13464	ROCK1	S648	R647Q	647	Missense	proximal	-1	no	35.012	32.795	EPSD	ICGC;COSMIC;CCLE	31.796	Down-regulation
AGC_DMPK_ROCK_ROCK1_ST	P19634	SLC9A1	Q13464	ROCK1	S648	Y649H	649	Missense	proximal	1	no	35.012	34.733	EPSD	ICGC;COSMIC	31.796	Down-regulation
AGC_DMPK_ROCK_ROCK1_ST	P19634	SLC9A1	Q13464	ROCK1	T653	R647Q	647	Missense	distal	-6	no	43.592	39.666	PhosphoSitePlus	ICGC;COSMIC;CCLE	31.796	Down-regulation
AGC_DMPK_ROCK_ROCK1_ST	P19634	SLC9A1	Q13464	ROCK1	T653	Y649H	649	Missense	distal	-4	no	43.592	43.447	PhosphoSitePlus	ICGC;COSMIC	31.796	Down-regulation
AGC_DMPK_ROCK_ROCK1_ST	P19634	SLC9A1	Q13464	ROCK1	T685	T685K	685	Missense	central	0	yes	32.153	0.000	EPSD	ICGC;COSMIC	31.796	Loss
AGC_DMPK_ROCK_ROCK1_ST	P19634	SLC9A1	Q13464	ROCK1	T685	H689Q	689	Missense	distal	4	no	32.153	31.302	EPSD	ICGC	31.796	Loss
AGC_DMPK_ROCK_ROCK1_ST	P19634	SLC9A1	Q13464	ROCK1	T685	P687T	687	Missense	proximal	2	no	32.153	33.871	EPSD	ICGC	31.796	Up-regulation
AGC_DMPK_ROCK_ROCK1_ST	Q9NRY4	ARHGAP35	Q13464	ROCK1	S443	L440R	440	Missense	distal	-3	no	21.577	33.049	EPSD	ICGC	31.796	Gain
AGC_DMPK_ROCK_ROCK1_ST	Q9NRY4	ARHGAP35	Q13464	ROCK1	T709	D708N	708	Missense	proximal	-1	no	30.413	31.852	EPSD	ICGC;COSMIC	31.796	Gain
AGC_DMPK_ROCK_ROCK1_ST	Q9NRY4	ARHGAP35	Q13464	ROCK1	S1010	D1008Y	1008	Missense	proximal	-2	no	30.057	37.746	EPSD	ICGC	31.796	Gain
AGC_DMPK_ROCK_ROCK1_ST	Q9NRY4	ARHGAP35	Q13464	ROCK1	S1150	S1153I	1153	Missense	distal	3	no	41.805	41.728	EPSD;PhosphoSitePlus	ICGC	31.796	Down-regulation
AGC_DMPK_ROCK_ROCK1_ST	Q9NRY4	ARHGAP35	Q13464	ROCK1	S1150	R1147C	1147	Missense	distal	-3	no	41.805	16.521	EPSD;PhosphoSitePlus	ICGC	31.796	Loss
AGC_DMPK_ROCK_ROCK1_ST	Q9NRY4	ARHGAP35	Q13464	ROCK1	S1170	R1167W	1167	Missense	distal	-3	no	40.317	31.155	EPSD	ICGC;COSMIC	31.796	Loss
AGC_DMPK_ROCK_ROCK1_ST	Q9NRY4	ARHGAP35	Q13464	ROCK1	S1170	R1172W	1172	Missense	proximal	2	no	40.317	38.429	EPSD	ICGC;COSMIC;GDSC;CCLE	31.796	Down-regulation
AGC_DMPK_ROCK_ROCK1_ST	Q9NRY4	ARHGAP35	Q13464	ROCK1	S1170	V1177M	1177	Missense	distal	7	no	40.317	40.225	EPSD	ICGC;COSMIC	31.796	Down-regulation
AGC_DMPK_ROCK_ROCK1_ST	Q9NRY4	ARHGAP35	Q13464	ROCK1	T1173	R1167W	1167	Missense	distal	-6	no	33.235	29.908	PhosphoSitePlus;EPSD	ICGC;COSMIC	31.796	Loss
AGC_DMPK_ROCK_ROCK1_ST	Q9NRY4	ARHGAP35	Q13464	ROCK1	T1173	R1172W	1172	Missense	proximal	-1	no	33.235	31.282	PhosphoSitePlus;EPSD	ICGC;COSMIC;GDSC;CCLE	31.796	Loss
AGC_DMPK_ROCK_ROCK1_ST	Q9NRY4	ARHGAP35	Q13464	ROCK1	T1173	V1177M	1177	Missense	distal	4	no	33.235	34.288	PhosphoSitePlus;EPSD	ICGC;COSMIC	31.796	Up-regulation
AGC_DMPK_ROCK_ROCK1_ST	Q9NRY4	ARHGAP35	Q13464	ROCK1	S1174	R1167W	1167	Missense	distal	-7	no	37.594	37.349	EPSD;PhosphoSitePlus	ICGC;COSMIC	31.796	Down-regulation
AGC_DMPK_ROCK_ROCK1_ST	Q9NRY4	ARHGAP35	Q13464	ROCK1	S1174	R1172W	1172	Missense	proximal	-2	no	37.594	36.508	EPSD;PhosphoSitePlus	ICGC;COSMIC;GDSC;CCLE	31.796	Down-regulation
AGC_DMPK_ROCK_ROCK1_ST	Q9NRY4	ARHGAP35	Q13464	ROCK1	S1174	D1181Y	1181	Missense	distal	7	no	37.594	37.534	EPSD;PhosphoSitePlus	ICGC;COSMIC	31.796	Down-regulation
AGC_DMPK_ROCK_ROCK1_ST	Q9NRY4	ARHGAP35	Q13464	ROCK1	S1174	V1177M	1177	Missense	distal	3	no	37.594	37.600	EPSD;PhosphoSitePlus	ICGC;COSMIC	31.796	Up-regulation
AGC_DMPK_ROCK_ROCK1_ST	Q9NRY4	ARHGAP35	Q13464	ROCK1	S1176	R1172W	1172	Missense	distal	-4	no	32.634	28.348	EPSD	ICGC;COSMIC;GDSC;CCLE	31.796	Loss
AGC_DMPK_ROCK_ROCK1_ST	Q9NRY4	ARHGAP35	Q13464	ROCK1	S1176	D1181Y	1181	Missense	distal	5	no	32.634	32.401	EPSD	ICGC;COSMIC	31.796	Down-regulation
AGC_DMPK_ROCK_ROCK1_ST	Q9NRY4	ARHGAP35	Q13464	ROCK1	S1176	V1177M	1177	Missense	proximal	1	no	32.634	32.541	EPSD	ICGC;COSMIC	31.796	Down-regulation
AGC_DMPK_ROCK_ROCK1_ST	Q9NRY4	ARHGAP35	Q13464	ROCK1	T1226	R1223S	1223	Missense	distal	-3	no	58.138	47.550	EPSD;PhosphoSitePlus	ICGC;COSMIC	31.796	Down-regulation
AGC_DMPK_ROCK_ROCK1_ST	Q9NRY4	ARHGAP35	Q13464	ROCK1	S1236	W1242L	1242	Missense	distal	6	no	40.710	40.333	EPSD;PhosphoSitePlus	ICGC;COSMIC	31.796	Down-regulation
AGC_DMPK_ROCK_ROCK1_ST	Q9NRY4	ARHGAP35	Q13464	ROCK1	S1290	R1284Q	1284	Missense	distal	-6	no	34.442	30.517	EPSD	ICGC;COSMIC	31.796	Loss
AGC_DMPK_ROCK_ROCK1_ST	Q9NRY4	ARHGAP35	Q13464	ROCK1	S1290	R1284L	1284	Missense	distal	-6	no	34.442	28.548	EPSD	ICGC;COSMIC	31.796	Loss
AGC_DMPK_ROCK_ROCK1_ST	Q9Y613	FHOD1	Q13464	ROCK1	S367	P374H	374	Missense	distal	7	no	38.259	37.410	EPSD	ICGC;COSMIC	31.796	Down-regulation
AGC_DMPK_ROCK_ROCK1_ST	Q9Y613	FHOD1	Q13464	ROCK1	T692	T690K	690	Missense	proximal	-2	no	30.371	35.894	EPSD	ICGC	31.796	Gain
AGC_DMPK_ROCK_ROCK1_ST	Q9Y613	FHOD1	Q13464	ROCK1	T693	T690K	690	Missense	distal	-3	no	30.722	34.541	EPSD	ICGC	31.796	Gain
AGC_DMPK_ROCK_ROCK1_ST	Q9Y613	FHOD1	Q13464	ROCK1	T1010	R1011Q	1011	Missense	proximal	1	no	32.912	33.411	EPSD	ICGC;COSMIC	31.796	Up-regulation
AGC_DMPK_ROCK_ROCK1_ST	Q9Y613	FHOD1	Q13464	ROCK1	T1010	R1007S	1007	Missense	distal	-3	no	32.912	22.323	EPSD	ICGC	31.796	Loss
AGC_DMPK_ROCK_ROCK1_ST	Q9Y613	FHOD1	Q13464	ROCK1	T1010	R1011L	1011	Missense	proximal	1	no	32.912	34.296	EPSD	ICGC;COSMIC	31.796	Up-regulation
AGC_DMPK_ROCK_ROCK1_ST	Q9Y613	FHOD1	Q13464	ROCK1	T1010	R1005S	1005	Missense	distal	-5	no	32.912	30.639	EPSD	ICGC;COSMIC	31.796	Loss
AGC_DMPK_ROCK_ROCK1_ST	Q9Y613	FHOD1	Q13464	ROCK1	T1010	E1006K	1006	Missense	distal	-4	no	32.912	36.579	EPSD	ICGC;COSMIC	31.796	Up-regulation
AGC_DMPK_ROCK_ROCK1_ST	Q9Y613	FHOD1	Q13464	ROCK1	T1016	R1011Q	1011	Missense	distal	-5	no	34.517	33.044	EPSD	ICGC;COSMIC	31.796	Down-regulation
AGC_DMPK_ROCK_ROCK1_ST	Q9Y613	FHOD1	Q13464	ROCK1	T1016	R1011L	1011	Missense	distal	-5	no	34.517	31.593	EPSD	ICGC;COSMIC	31.796	Loss
AGC_DMPK_ROCK_ROCK1_ST	Q9Y613	FHOD1	Q13464	ROCK1	T1016	F1021L	1021	Missense	distal	5	no	34.517	34.531	EPSD	ICGC;COSMIC	31.796	Up-regulation
AGC_DMPK_ROCK_ROCK1_ST	Q9Y613	FHOD1	Q13464	ROCK1	S1052	D1048E	1048	Missense	distal	-4	no	37.714	36.548	EPSD	ICGC;CCLE	31.796	Down-regulation
AGC_DMPK_ROCK_ROCK1_ST	Q9Y613	FHOD1	Q13464	ROCK1	S1055	D1048E	1048	Missense	distal	-7	no	34.981	35.005	EPSD	ICGC;CCLE	31.796	Up-regulation
AGC_DMPK_ROCK_ROCK1_ST	Q9Y613	FHOD1	Q13464	ROCK1	S1131	R1135H	1135	Missense	distal	4	no	37.343	36.755	EPSD;PhosphoSitePlus	ICGC;COSMIC	31.796	Down-regulation
AGC_DMPK_ROCK_ROCK1_ST	Q9Y613	FHOD1	Q13464	ROCK1	S1131	R1130C	1130	Missense	proximal	-1	no	37.343	33.062	EPSD;PhosphoSitePlus	ICGC	31.796	Down-regulation
AGC_DMPK_ROCK_ROCK1_ST	Q9Y613	FHOD1	Q13464	ROCK1	S1131	R1130H	1130	Missense	proximal	-1	no	37.343	34.774	EPSD;PhosphoSitePlus	ICGC;COSMIC;CCLE	31.796	Down-regulation
AGC_DMPK_ROCK_ROCK1_ST	Q9Y613	FHOD1	Q13464	ROCK1	S1137	R1135H	1135	Missense	proximal	-2	no	44.904	33.769	PhosphoSitePlus;EPSD	ICGC;COSMIC	31.796	Down-regulation
AGC_DMPK_ROCK_ROCK1_ST	Q9Y613	FHOD1	Q13464	ROCK1	S1137	R1130C	1130	Missense	distal	-7	no	44.904	44.651	PhosphoSitePlus;EPSD	ICGC	31.796	Down-regulation
AGC_DMPK_ROCK_ROCK1_ST	Q9Y613	FHOD1	Q13464	ROCK1	S1137	R1130H	1130	Missense	distal	-7	no	44.904	44.742	PhosphoSitePlus;EPSD	ICGC;COSMIC;CCLE	31.796	Down-regulation
AGC_DMPK_ROCK_ROCK1_ST	Q9Y613	FHOD1	Q13464	ROCK1	T1141	R1135H	1135	Missense	distal	-6	no	50.072	46.553	EPSD;PhosphoSitePlus	ICGC;COSMIC	31.796	Down-regulation
AGC_DMPK_ROCK_ROCK1_ST	Q8N264	ARHGAP24	Q13464	ROCK1	T97	L104V	104	Missense	distal	7	no	39.339	39.921	EPSD	ICGC;COSMIC	31.796	Up-regulation
AGC_DMPK_ROCK_ROCK1_ST	Q8N264	ARHGAP24	Q13464	ROCK1	T97	Y103C	103	Missense	distal	6	no	39.339	39.158	EPSD	ICGC;COSMIC;GDSC;CCLE	31.796	Down-regulation
AGC_DMPK_ROCK_ROCK1_ST	Q8N264	ARHGAP24	Q13464	ROCK1	T97	N99K	99	Missense	proximal	2	no	39.339	41.335	EPSD	ICGC;COSMIC	31.796	Up-regulation
AGC_DMPK_ROCK_ROCK1_ST	Q8N264	ARHGAP24	Q13464	ROCK1	S102	N99K	99	Missense	distal	-3	no	28.843	34.412	EPSD	ICGC;COSMIC	31.796	Gain
AGC_DMPK_ROCK_ROCK1_ST	Q8N264	ARHGAP24	Q13464	ROCK1	S108	L104V	104	Missense	distal	-4	no	34.488	34.618	EPSD	ICGC;COSMIC	31.796	Up-regulation
AGC_DMPK_ROCK_ROCK1_ST	Q8N264	ARHGAP24	Q13464	ROCK1	S108	Y103C	103	Missense	distal	-5	no	34.488	30.181	EPSD	ICGC;COSMIC;GDSC;CCLE	31.796	Loss
AGC_DMPK_ROCK_ROCK1_ST	Q8N264	ARHGAP24	Q13464	ROCK1	S381	K378R	378	Missense	distal	-3	no	29.667	33.378	EPSD	ICGC;COSMIC	31.796	Gain
AGC_DMPK_ROCK_ROCK1_ST	Q8N264	ARHGAP24	Q13464	ROCK1	S391	A394V	394	Missense	distal	3	no	35.961	35.962	PhosphoSitePlus;EPSD	ICGC	31.796	Up-regulation
AGC_DMPK_ROCK_ROCK1_ST	Q8N264	ARHGAP24	Q13464	ROCK1	S391	A394D	394	Missense	distal	3	no	35.961	35.910	PhosphoSitePlus;EPSD	ICGC	31.796	Down-regulation
AGC_DMPK_ROCK_ROCK1_ST	Q8N264	ARHGAP24	Q13464	ROCK1	S402	V407A	407	Missense	distal	5	no	34.490	33.946	EPSD;PhosphoSitePlus	ICGC	31.796	Down-regulation
AGC_DMPK_ROCK_ROCK1_ST	Q8N264	ARHGAP24	Q13464	ROCK1	S413	V407A	407	Missense	distal	-6	no	30.082	32.113	EPSD;PhosphoSitePlus	ICGC	31.796	Gain
AGC_DMPK_ROCK_ROCK1_ST	Q8N264	ARHGAP24	Q13464	ROCK1	S437	S439R	439	Missense	proximal	2	no	33.437	34.303	EPSD;PhosphoSitePlus	ICGC;COSMIC	31.796	Up-regulation
AGC_DMPK_ROCK_ROCK1_ST	Q8N264	ARHGAP24	Q13464	ROCK1	S437	G436R	436	Missense	proximal	-1	no	33.437	33.996	EPSD;PhosphoSitePlus	ICGC;COSMIC	31.796	Up-regulation
AGC_DMPK_ROCK_ROCK1_ST	Q8N264	ARHGAP24	Q13464	ROCK1	S437	G431W	431	Missense	distal	-6	no	33.437	31.177	EPSD;PhosphoSitePlus	ICGC	31.796	Loss
AGC_DMPK_ROCK_ROCK1_ST	Q8N264	ARHGAP24	Q13464	ROCK1	T452	P453H	453	Missense	proximal	1	no	33.342	32.966	EPSD;PhosphoSitePlus	ICGC;COSMIC	31.796	Down-regulation
AGC_DMPK_ROCK_ROCK1_ST	Q8N264	ARHGAP24	Q13464	ROCK1	T452	N454S	454	Missense	proximal	2	no	33.342	34.146	EPSD;PhosphoSitePlus	ICGC;COSMIC	31.796	Up-regulation
AGC_DMPK_ROCK_ROCK1_ST	Q8N264	ARHGAP24	Q13464	ROCK1	S462	R461G	461	Missense	proximal	-1	no	38.776	38.218	EPSD	ICGC	31.796	Down-regulation
AGC_DMPK_ROCK_ROCK1_ST	Q8N264	ARHGAP24	Q13464	ROCK1	S463	R461G	461	Missense	proximal	-2	no	38.548	28.792	EPSD	ICGC	31.796	Loss
AGC_DMPK_ROCK_ROCK1_ST	Q8N264	ARHGAP24	Q13464	ROCK1	S464	R461G	461	Missense	distal	-3	no	40.351	30.160	EPSD	ICGC	31.796	Loss
AGC_DMPK_ROCK_ROCK1_ST	Q8N264	ARHGAP24	Q13464	ROCK1	S530	N527K	527	Missense	distal	-3	no	36.043	41.613	EPSD	ICGC	31.796	Up-regulation
AGC_DMPK_ROCK_ROCK1_ST	Q8N264	ARHGAP24	Q13464	ROCK1	T624	R622H	622	Missense	proximal	-2	no	38.769	27.633	EPSD	ICGC	31.796	Loss
AGC_DMPK_ROCK_ROCK1_ST	Q8N264	ARHGAP24	Q13464	ROCK1	S625	R622H	622	Missense	distal	-3	no	38.369	23.759	EPSD	ICGC	31.796	Loss
AGC_DMPK_ROCK_ROCK1_ST	Q8N264	ARHGAP24	Q13464	ROCK1	S627	R622H	622	Missense	distal	-5	no	35.021	33.793	EPSD	ICGC	31.796	Down-regulation
AGC_DMPK_ROCK_ROCK1_ST	P15311	EZR	Q13464	ROCK1	S66	L59M	59	Missense	distal	-7	no	37.158	37.131	EPSD	ICGC	31.796	Down-regulation
AGC_DMPK_ROCK_ROCK1_ST	P15311	EZR	Q13464	ROCK1	S66	A67V	67	Missense	proximal	1	no	37.158	37.514	EPSD	ICGC	31.796	Up-regulation
AGC_DMPK_ROCK_ROCK1_ST	P15311	EZR	Q13464	ROCK1	S66	V65G	65	Missense	proximal	-1	no	37.158	39.576	EPSD	ICGC;COSMIC	31.796	Up-regulation
AGC_DMPK_ROCK_ROCK1_ST	P15311	EZR	Q13464	ROCK1	T332	E334K	334	Missense	proximal	2	no	33.836	37.506	EPSD	ICGC;COSMIC	31.796	Up-regulation
AGC_DMPK_ROCK_ROCK1_ST	P15311	EZR	Q13464	ROCK1	S366	Q368K	368	Missense	proximal	2	no	37.457	38.939	EPSD	ICGC;COSMIC	31.796	Up-regulation
AGC_DMPK_ROCK_ROCK1_ST	P15311	EZR	Q13464	ROCK1	S366	A361E	361	Missense	distal	-5	no	37.457	36.614	EPSD	ICGC	31.796	Down-regulation
AGC_DMPK_ROCK_ROCK1_ST	P15311	EZR	Q13464	ROCK1	T567	T567M	567	Missense	central	0	yes	33.323	0.000	PhosphoSitePlus	ICGC;COSMIC	31.796	Loss
AGC_DMPK_ROCK_ROCK1_ST	P15311	EZR	Q13464	ROCK1	T567	Q573K	573	Missense	distal	6	no	33.323	32.613	PhosphoSitePlus	ICGC	31.796	Down-regulation
AGC_DMPK_ROCK_ROCK1_ST	P15311	EZR	Q13464	ROCK1	T576	R579H	579	Missense	distal	3	no	32.964	32.868	EPSD	ICGC;COSMIC	31.796	Down-regulation
AGC_DMPK_ROCK_ROCK1_ST	P15311	EZR	Q13464	ROCK1	T576	N575K	575	Missense	proximal	-1	no	32.964	35.334	EPSD	ICGC	31.796	Up-regulation
AGC_DMPK_ROCK_ROCK1_ST	P15311	EZR	Q13464	ROCK1	T576	Q573K	573	Missense	distal	-3	no	32.964	34.137	EPSD	ICGC	31.796	Up-regulation
AGC_DMPK_ROCK_ROCK1_ST	P14136	GFAP	Q13464	ROCK1	T7	R12C	12	Missense	distal	5	no	30.838	31.810	EPSD;PhosphoSitePlus	ICGC	31.796	Gain
AGC_DMPK_ROCK_ROCK1_ST	P14136	GFAP	Q13464	ROCK1	S13	R12C	12	Missense	proximal	-1	no	41.059	36.778	EPSD;PhosphoSitePlus	ICGC	31.796	Down-regulation
AGC_DMPK_ROCK_ROCK1_ST	P14136	GFAP	Q13464	ROCK1	S16	R12C	12	Missense	distal	-4	no	33.905	28.735	EPSD	ICGC	31.796	Loss
AGC_DMPK_ROCK_ROCK1_ST	P14136	GFAP	Q13464	ROCK1	S38	R36H	36	Missense	proximal	-2	no	39.789	28.654	PhosphoSitePlus;EPSD	ICGC;COSMIC	31.796	Loss
AGC_DMPK_ROCK_ROCK1_ST	P14136	GFAP	Q13464	ROCK1	S38	P33T	33	Missense	distal	-5	no	39.789	41.342	PhosphoSitePlus;EPSD	ICGC	31.796	Up-regulation
AGC_DMPK_ROCK_ROCK1_ST	P60484	PTEN	Q13464	ROCK1	S179	Y177C	177	Missense	proximal	-2	no	43.618	15.338	EPSD	ICGC;COSMIC	31.796	Loss
AGC_DMPK_ROCK_ROCK1_ST	P60484	PTEN	Q13464	ROCK1	S179	Y177S	177	Missense	proximal	-2	no	43.618	35.195	EPSD	ICGC;COSMIC	31.796	Down-regulation
AGC_DMPK_ROCK_ROCK1_ST	P60484	PTEN	Q13464	ROCK1	S179	Y178S	178	Missense	proximal	-1	no	43.618	45.232	EPSD	ICGC;COSMIC	31.796	Up-regulation
AGC_DMPK_ROCK_ROCK1_ST	P60484	PTEN	Q13464	ROCK1	S179	V175L	175	Missense	distal	-4	no	43.618	43.487	EPSD	ICGC;COSMIC	31.796	Down-regulation
AGC_DMPK_ROCK_ROCK1_ST	P60484	PTEN	Q13464	ROCK1	S179	H185D	185	Missense	distal	6	no	43.618	43.949	EPSD	ICGC;COSMIC	31.796	Up-regulation
AGC_DMPK_ROCK_ROCK1_ST	P60484	PTEN	Q13464	ROCK1	S227	S226A	226	Missense	proximal	-1	no	33.700	32.070	EPSD	ICGC;COSMIC	31.796	Down-regulation
AGC_DMPK_ROCK_ROCK1_ST	P60484	PTEN	Q13464	ROCK1	S229	S226A	226	Missense	distal	-3	no	35.730	32.254	PhosphoSitePlus;EPSD	ICGC;COSMIC	31.796	Down-regulation
AGC_DMPK_ROCK_ROCK1_ST	P60484	PTEN	Q13464	ROCK1	T232	S226A	226	Missense	distal	-6	no	37.654	37.391	EPSD;PhosphoSitePlus	ICGC;COSMIC	31.796	Down-regulation
AGC_DMPK_ROCK_ROCK1_ST	P60484	PTEN	Q13464	ROCK1	S338	L345Q	345	Missense	distal	7	no	42.148	41.830	EPSD	ICGC;COSMIC	31.796	Down-regulation
AGC_DMPK_ROCK_ROCK1_ST	P60484	PTEN	Q13464	ROCK1	S338	L345M	345	Missense	distal	7	no	42.148	42.638	EPSD	ICGC;COSMIC	31.796	Up-regulation
AGC_DMPK_ROCK_ROCK1_ST	P60484	PTEN	Q13464	ROCK1	S338	L345P	345	Missense	distal	7	no	42.148	42.594	EPSD	ICGC;COSMIC	31.796	Up-regulation
AGC_DMPK_ROCK_ROCK1_ST	P60484	PTEN	Q13464	ROCK1	S338	D331N	331	Missense	distal	-7	no	42.148	42.115	EPSD	ICGC;COSMIC	31.796	Down-regulation
AGC_DMPK_ROCK_ROCK1_ST	P60484	PTEN	Q13464	ROCK1	S338	R335G	335	Missense	distal	-3	no	42.148	31.958	EPSD	ICGC;COSMIC	31.796	Down-regulation
AGC_DMPK_ROCK_ROCK1_ST	P60484	PTEN	Q13464	ROCK1	T363	S360R	360	Missense	distal	-3	no	21.736	32.325	EPSD	ICGC	31.796	Gain
AGC_DMPK_ROCK_ROCK1_ST	P17661	DES	Q13464	ROCK1	S12	R16H	16	Missense	distal	4	no	38.150	37.562	EPSD;PhosphoSitePlus	ICGC;COSMIC	31.796	Down-regulation
AGC_DMPK_ROCK_ROCK1_ST	P17661	DES	Q13464	ROCK1	S13	R16H	16	Missense	distal	3	no	32.838	32.742	EPSD	ICGC;COSMIC	31.796	Down-regulation
AGC_DMPK_ROCK_ROCK1_ST	P17661	DES	Q13464	ROCK1	S13	G20W	20	Missense	distal	7	no	32.838	33.016	EPSD	ICGC;COSMIC	31.796	Up-regulation
AGC_DMPK_ROCK_ROCK1_ST	P17661	DES	Q13464	ROCK1	T17	P22L	22	Missense	distal	5	no	38.877	39.110	PhosphoSitePlus;EPSD	ICGC;COSMIC	31.796	Up-regulation
AGC_DMPK_ROCK_ROCK1_ST	P17661	DES	Q13464	ROCK1	T17	R16H	16	Missense	proximal	-1	no	38.877	36.309	PhosphoSitePlus;EPSD	ICGC;COSMIC	31.796	Down-regulation
AGC_DMPK_ROCK_ROCK1_ST	P17661	DES	Q13464	ROCK1	T17	G20W	20	Missense	distal	3	no	38.877	38.754	PhosphoSitePlus;EPSD	ICGC;COSMIC	31.796	Down-regulation
AGC_DMPK_ROCK_ROCK1_ST	P17661	DES	Q13464	ROCK1	S57	R58L	58	Missense	proximal	1	no	30.458	31.842	EPSD	ICGC;COSMIC	31.796	Gain
AGC_DMPK_ROCK_ROCK1_ST	P17661	DES	Q13464	ROCK1	T59	V53M	53	Missense	distal	-6	no	28.415	32.248	EPSD	ICGC;COSMIC	31.796	Gain
AGC_DMPK_ROCK_ROCK1_ST	P17661	DES	Q13464	ROCK1	S60	V53M	53	Missense	distal	-7	no	45.968	45.992	EPSD;PhosphoSitePlus	ICGC;COSMIC	31.796	Up-regulation
AGC_DMPK_ROCK_ROCK1_ST	P17661	DES	Q13464	ROCK1	S60	T59M	59	Missense	proximal	-1	no	45.968	45.505	EPSD;PhosphoSitePlus	ICGC;COSMIC	31.796	Down-regulation
AGC_DMPK_ROCK_ROCK1_ST	P17661	DES	Q13464	ROCK1	S60	R58C	58	Missense	proximal	-2	no	45.968	13.109	EPSD;PhosphoSitePlus	ICGC;COSMIC	31.796	Loss
AGC_DMPK_ROCK_ROCK1_ST	P17661	DES	Q13464	ROCK1	S60	R58L	58	Missense	proximal	-2	no	45.968	32.377	EPSD;PhosphoSitePlus	ICGC;COSMIC	31.796	Down-regulation
AGC_DMPK_ROCK_ROCK1_ST	P17661	DES	Q13464	ROCK1	S81	G86C	86	Missense	distal	5	no	34.041	34.608	EPSD	ICGC	31.796	Up-regulation
AGC_DMPK_ROCK_ROCK1_ST	P17661	DES	Q13464	ROCK1	S438	S432T	432	Missense	distal	-6	no	32.643	33.410	EPSD	ICGC	31.796	Up-regulation
AGC_DMPK_ROCK_ROCK1_ST	P17661	DES	Q13464	ROCK1	S438	P433H	433	Missense	distal	-5	no	32.643	35.362	EPSD	ICGC;COSMIC	31.796	Up-regulation
AGC_DMPK_ROCK_ROCK1_ST	Q14CB8	ARHGAP19	Q13464	ROCK1	S422	S420L	420	Missense	proximal	-2	no	36.767	36.177	PhosphoSitePlus	ICGC;COSMIC	31.796	Down-regulation
AGC_DMPK_ROCK_ROCK1_ST	Q14CB8	ARHGAP19	Q13464	ROCK1	S422	R419H	419	Missense	distal	-3	no	36.767	22.156	PhosphoSitePlus	ICGC;COSMIC	31.796	Loss
AGC_DMPK_ROCK_ROCK1_ST	Q14CB8	ARHGAP19	Q13464	ROCK1	S422	R429W	429	Missense	distal	7	no	36.767	38.305	PhosphoSitePlus	ICGC;COSMIC	31.796	Up-regulation
AGC_DMPK_ROCK_ROCK1_ST	Q14CB8	ARHGAP19	Q13464	ROCK1	S424	S420L	420	Missense	distal	-4	no	34.748	33.937	EPSD	ICGC;COSMIC	31.796	Down-regulation
AGC_DMPK_ROCK_ROCK1_ST	Q14CB8	ARHGAP19	Q13464	ROCK1	S424	R419H	419	Missense	distal	-5	no	34.748	33.520	EPSD	ICGC;COSMIC	31.796	Down-regulation
AGC_DMPK_ROCK_ROCK1_ST	Q14CB8	ARHGAP19	Q13464	ROCK1	S424	R429W	429	Missense	distal	5	no	34.748	35.648	EPSD	ICGC;COSMIC	31.796	Up-regulation
AGC_DMPK_ROCK_ROCK1_ST	O14950	MYL12B	Q13464	ROCK1	T19	T19A	19	Missense	central	0	yes	51.827	0.000	EPSD;PhosphoSitePlus	ICGC;COSMIC	31.796	Loss
AGC_DMPK_ROCK_ROCK1_ST	O14950	MYL12B	Q13464	ROCK1	S20	T19A	19	Missense	proximal	-1	no	40.125	39.073	PhosphoSitePlus;EPSD	ICGC;COSMIC	31.796	Down-regulation
AGC_DMPK_ROCK_ROCK1_ST	Q16555	DPYSL2	Q13464	ROCK1	S30	D28Y	28	Missense	proximal	-2	no	30.398	38.088	EPSD	ICGC;COSMIC	31.796	Gain
AGC_DMPK_ROCK_ROCK1_ST	Q16555	DPYSL2	Q13464	ROCK1	S363	R361W	361	Missense	proximal	-2	no	35.420	34.335	EPSD	ICGC;COSMIC	31.796	Down-regulation
AGC_DMPK_ROCK_ROCK1_ST	O14744	PRMT5	Q13464	ROCK1	S15	G11V	11	Missense	distal	-4	no	39.096	38.258	EPSD	ICGC	31.796	Down-regulation
AGC_DMPK_ROCK_ROCK1_ST	O14744	PRMT5	Q13464	ROCK1	S16	G11V	11	Missense	distal	-5	no	37.015	34.400	EPSD	ICGC	31.796	Down-regulation
AGC_DMPK_ROCK_ROCK1_ST	P24844	MYL9	Q13464	ROCK1	T10	R17L	17	Missense	distal	7	no	31.749	33.072	EPSD	ICGC;COSMIC	31.796	Gain
AGC_DMPK_ROCK_ROCK1_ST	P24844	MYL9	Q13464	ROCK1	T11	R17L	17	Missense	distal	6	no	31.345	32.446	EPSD	ICGC;COSMIC	31.796	Gain
AGC_DMPK_ROCK_ROCK1_ST	P24844	MYL9	Q13464	ROCK1	T19	R17L	17	Missense	proximal	-2	no	51.361	37.771	PhosphoSitePlus;EPSD	ICGC;COSMIC	31.796	Down-regulation
AGC_DMPK_ROCK_ROCK1_ST	P24844	MYL9	Q13464	ROCK1	T19	R14W	14	Missense	distal	-5	no	51.361	49.079	PhosphoSitePlus;EPSD	ICGC;COSMIC	31.796	Down-regulation
AGC_DMPK_ROCK_ROCK1_ST	P24844	MYL9	Q13464	ROCK1	S20	R17L	17	Missense	distal	-3	no	39.387	27.915	EPSD;PhosphoSitePlus	ICGC;COSMIC	31.796	Loss
AGC_DMPK_ROCK_ROCK1_ST	P24844	MYL9	Q13464	ROCK1	S20	R14W	14	Missense	distal	-6	no	39.387	36.060	EPSD;PhosphoSitePlus	ICGC;COSMIC	31.796	Down-regulation
AGC_DMPK_ROCK_ROCK1_ST	P07737	PFN1	Q13464	ROCK1	S30	W32R	32	Missense	proximal	2	no	33.777	35.665	EPSD	ICGC;COSMIC	31.796	Up-regulation
AGC_DMPK_ROCK_ROCK1_ST	P35611	ADD1	Q13464	ROCK1	S59	A66S	66	Missense	distal	7	no	34.118	34.275	EPSD	ICGC	31.796	Up-regulation
AGC_DMPK_ROCK_ROCK1_ST	P35611	ADD1	Q13464	ROCK1	S59	M52I	52	Missense	distal	-7	no	34.118	34.181	EPSD	ICGC	31.796	Up-regulation
AGC_DMPK_ROCK_ROCK1_ST	P35611	ADD1	Q13464	ROCK1	S59	V58A	58	Missense	proximal	-1	no	34.118	34.724	EPSD	ICGC;COSMIC	31.796	Up-regulation
AGC_DMPK_ROCK_ROCK1_ST	P35611	ADD1	Q13464	ROCK1	S59	M60K	60	Missense	proximal	1	no	34.118	33.110	EPSD	ICGC;COSMIC	31.796	Down-regulation
AGC_DMPK_ROCK_ROCK1_ST	P35611	ADD1	Q13464	ROCK1	S133	S133F	133	Missense	central	0	yes	40.124	0.000	EPSD	ICGC	31.796	Loss
AGC_DMPK_ROCK_ROCK1_ST	P35611	ADD1	Q13464	ROCK1	T445	R452W	452	Missense	distal	7	no	31.740	33.278	PhosphoSitePlus;EPSD	ICGC	31.796	Gain
AGC_DMPK_ROCK_ROCK1_ST	P35611	ADD1	Q13464	ROCK1	T445	G451C	451	Missense	distal	6	no	31.740	31.864	PhosphoSitePlus;EPSD	ICGC;COSMIC	31.796	Gain
AGC_DMPK_ROCK_ROCK1_ST	P35611	ADD1	Q13464	ROCK1	T445	N449S	449	Missense	distal	4	no	31.740	32.370	PhosphoSitePlus;EPSD	ICGC	31.796	Gain
AGC_DMPK_ROCK_ROCK1_ST	P35611	ADD1	Q13464	ROCK1	T480	D476N	476	Missense	distal	-4	no	36.112	36.474	EPSD;PhosphoSitePlus	ICGC;COSMIC	31.796	Up-regulation
AGC_DMPK_ROCK_ROCK1_ST	P35611	ADD1	Q13464	ROCK1	T482	D476N	476	Missense	distal	-6	no	30.551	31.965	EPSD	ICGC;COSMIC	31.796	Gain
AGC_DMPK_ROCK_ROCK1_ST	P35611	ADD1	Q13464	ROCK1	S483	D476N	476	Missense	distal	-7	no	36.513	36.480	EPSD	ICGC;COSMIC	31.796	Down-regulation
AGC_DMPK_ROCK_ROCK1_ST	P35611	ADD1	Q13464	ROCK1	S726	R723C	723	Missense	distal	-3	no	34.478	9.193	EPSD	ICGC;COSMIC	31.796	Loss
AGC_DMPK_ROCK_ROCK1_ST	P35611	ADD1	Q13464	ROCK1	S726	P725L	725	Missense	proximal	-1	no	34.478	33.744	EPSD	ICGC;COSMIC	31.796	Down-regulation
AGC_DMPK_ROCK_ROCK1_ST	P26038	MSN	Q13464	ROCK1	S56	Q50K	50	Missense	distal	-6	no	29.460	32.465	EPSD	ICGC;COSMIC	31.796	Gain
AGC_DMPK_ROCK_ROCK1_ST	P26038	MSN	Q13464	ROCK1	S74	R81H	81	Missense	distal	7	no	33.231	34.151	EPSD	ICGC;COSMIC	31.796	Up-regulation
AGC_DMPK_ROCK_ROCK1_ST	P26038	MSN	Q13464	ROCK1	S74	K79N	79	Missense	distal	5	no	33.231	33.963	EPSD	ICGC;COSMIC	31.796	Up-regulation
AGC_DMPK_ROCK_ROCK1_ST	P26038	MSN	Q13464	ROCK1	S504	D497Y	497	Missense	distal	-7	no	36.774	36.776	EPSD	ICGC	31.796	Up-regulation
AGC_DMPK_ROCK_ROCK1_ST	P26038	MSN	Q13464	ROCK1	T510	R517C	517	Missense	distal	7	no	30.773	32.151	EPSD	ICGC	31.796	Gain
AGC_DMPK_ROCK_ROCK1_ST	P26038	MSN	Q13464	ROCK1	T510	R517L	517	Missense	distal	7	no	30.773	32.095	EPSD	ICGC	31.796	Gain
AGC_DMPK_ROCK_ROCK1_ST	P26038	MSN	Q13464	ROCK1	T558	D554N	554	Missense	distal	-4	no	34.154	34.515	PhosphoSitePlus	ICGC;COSMIC	31.796	Up-regulation
AGC_DMPK_ROCK_ROCK1_ST	P26038	MSN	Q13464	ROCK1	T558	T558I	558	Missense	central	0	yes	34.154	0.000	PhosphoSitePlus	ICGC;COSMIC	31.796	Loss
AGC_DMPK_ROCK_ROCK1_ST	O60237	PPP1R12B	Q13464	ROCK1	S51	V54F	54	Missense	distal	3	no	41.048	40.958	EPSD	ICGC	31.796	Down-regulation
AGC_DMPK_ROCK_ROCK1_ST	O60237	PPP1R12B	Q13464	ROCK1	S472	G465C	465	Missense	distal	-7	no	36.366	36.277	EPSD	ICGC	31.796	Down-regulation
AGC_DMPK_ROCK_ROCK1_ST	O60237	PPP1R12B	Q13464	ROCK1	S472	R476Q	476	Missense	distal	4	no	36.366	34.927	EPSD	ICGC;COSMIC;CCLE	31.796	Down-regulation
AGC_DMPK_ROCK_ROCK1_ST	O60237	PPP1R12B	Q13464	ROCK1	S473	R476Q	476	Missense	distal	3	no	32.914	32.731	EPSD	ICGC;COSMIC;CCLE	31.796	Down-regulation
AGC_DMPK_ROCK_ROCK1_ST	O60237	PPP1R12B	Q13464	ROCK1	S618	S618F	618	Missense	central	0	yes	37.825	0.000	EPSD	ICGC	31.796	Loss
AGC_DMPK_ROCK_ROCK1_ST	O60237	PPP1R12B	Q13464	ROCK1	S618	R624L	624	Missense	distal	6	no	37.825	38.927	EPSD	ICGC;COSMIC;GDSC;CCLE	31.796	Up-regulation
AGC_DMPK_ROCK_ROCK1_ST	O60237	PPP1R12B	Q13464	ROCK1	S618	R617S	617	Missense	proximal	-1	no	37.825	37.085	EPSD	ICGC;COSMIC	31.796	Down-regulation
AGC_DMPK_ROCK_ROCK1_ST	O60237	PPP1R12B	Q13464	ROCK1	S618	K615E	615	Missense	distal	-3	no	37.825	29.381	EPSD	ICGC;COSMIC	31.796	Loss
AGC_DMPK_ROCK_ROCK1_ST	O60237	PPP1R12B	Q13464	ROCK1	T621	S618F	618	Missense	distal	-3	no	33.128	28.210	EPSD	ICGC	31.796	Loss
AGC_DMPK_ROCK_ROCK1_ST	O60237	PPP1R12B	Q13464	ROCK1	T621	E626D	626	Missense	distal	5	no	33.128	33.274	EPSD	ICGC;COSMIC	31.796	Up-regulation
AGC_DMPK_ROCK_ROCK1_ST	O60237	PPP1R12B	Q13464	ROCK1	T621	R624L	624	Missense	distal	3	no	33.128	32.832	EPSD	ICGC;COSMIC;GDSC;CCLE	31.796	Down-regulation
AGC_DMPK_ROCK_ROCK1_ST	O60237	PPP1R12B	Q13464	ROCK1	T621	R617S	617	Missense	distal	-4	no	33.128	30.181	EPSD	ICGC;COSMIC	31.796	Loss
AGC_DMPK_ROCK_ROCK1_ST	O60237	PPP1R12B	Q13464	ROCK1	T621	K615E	615	Missense	distal	-6	no	33.128	26.693	EPSD	ICGC;COSMIC	31.796	Loss
AGC_DMPK_ROCK_ROCK1_ST	O60237	PPP1R12B	Q13464	ROCK1	T642	R635C	635	Missense	distal	-7	no	35.241	34.987	EPSD	ICGC;COSMIC	31.796	Down-regulation
AGC_DMPK_ROCK_ROCK1_ST	O60237	PPP1R12B	Q13464	ROCK1	S839	R836M	836	Missense	distal	-3	no	34.284	26.770	EPSD	ICGC;COSMIC	31.796	Loss
AGC_DMPK_ROCK_ROCK1_ST	O60237	PPP1R12B	Q13464	ROCK1	S839	L834V	834	Missense	distal	-5	no	34.284	32.564	EPSD	ICGC	31.796	Down-regulation
AGC_DMPK_ROCK_ROCK1_ST	O60237	PPP1R12B	Q13464	ROCK1	S839	S835Y	835	Missense	distal	-4	no	34.284	34.395	EPSD	ICGC;COSMIC	31.796	Up-regulation
AGC_DMPK_ROCK_ROCK1_ST	O60237	PPP1R12B	Q13464	ROCK1	S855	R853L	853	Missense	proximal	-2	no	33.364	19.774	EPSD	ICGC	31.796	Loss
AGC_DMPK_ROCK_ROCK1_ST	O60237	PPP1R12B	Q13464	ROCK1	S855	R859L	859	Missense	distal	4	no	33.364	31.354	EPSD	ICGC	31.796	Loss
AGC_DMPK_ROCK_ROCK1_ST	O60237	PPP1R12B	Q13464	ROCK1	T869	R863Q	863	Missense	distal	-6	no	40.474	36.549	EPSD	ICGC;COSMIC;GDSC	31.796	Down-regulation
AGC_DMPK_ROCK_ROCK1_ST	O60237	PPP1R12B	Q13464	ROCK1	T869	T869I	869	Missense	central	0	yes	40.474	0.000	EPSD	ICGC	31.796	Loss
AGC_DMPK_ROCK_ROCK1_ST	O60237	PPP1R12B	Q13464	ROCK1	S947	E943D	943	Missense	distal	-4	no	34.156	35.322	EPSD	ICGC	31.796	Up-regulation
AGC_DMPK_ROCK_ROCK1_ST	O60237	PPP1R12B	Q13464	ROCK1	S947	M946I	946	Missense	proximal	-1	no	34.156	32.620	EPSD	ICGC	31.796	Down-regulation
AGC_DMPK_ROCK_ROCK1_ST	O43293	DAPK3	Q13464	ROCK1	S50	R48L	48	Missense	proximal	-2	no	48.189	34.598	EPSD	ICGC;COSMIC	31.796	Down-regulation
AGC_DMPK_ROCK_ROCK1_ST	O43293	DAPK3	Q13464	ROCK1	S50	R47S	47	Missense	distal	-3	no	48.189	37.600	EPSD	ICGC	31.796	Down-regulation
AGC_DMPK_ROCK_ROCK1_ST	O43293	DAPK3	Q13464	ROCK1	T265	R262Q	262	Missense	distal	-3	no	43.501	38.618	PhosphoSitePlus;EPSD	ICGC;COSMIC	31.796	Down-regulation
AGC_DMPK_ROCK_ROCK1_ST	O43293	DAPK3	Q13464	ROCK1	T265	S269R	269	Missense	distal	4	no	43.501	44.219	PhosphoSitePlus;EPSD	ICGC	31.796	Up-regulation
AGC_DMPK_ROCK_ROCK1_ST	O43293	DAPK3	Q13464	ROCK1	T265	P260L	260	Missense	distal	-5	no	43.501	44.524	PhosphoSitePlus;EPSD	ICGC	31.796	Up-regulation
AGC_DMPK_ROCK_ROCK1_ST	O43293	DAPK3	Q13464	ROCK1	S312	H310Y	310	Missense	proximal	-2	no	26.136	32.694	EPSD	ICGC	31.796	Gain
AGC_DMPK_ROCK_ROCK1_ST	P08670	VIM	Q13464	ROCK1	S25	P24L	24	Missense	proximal	-1	no	34.195	33.461	EPSD	ICGC;COSMIC	31.796	Down-regulation
AGC_DMPK_ROCK_ROCK1_ST	P08670	VIM	Q13464	ROCK1	S25	P18T	18	Missense	distal	-7	no	34.195	34.328	EPSD	ICGC;COSMIC	31.796	Up-regulation
AGC_DMPK_ROCK_ROCK1_ST	P08670	VIM	Q13464	ROCK1	S25	V31A	31	Missense	distal	6	no	34.195	33.920	EPSD	ICGC	31.796	Down-regulation
AGC_DMPK_ROCK_ROCK1_ST	P08670	VIM	Q13464	ROCK1	T32	V31A	31	Missense	proximal	-1	no	37.377	37.984	EPSD	ICGC	31.796	Up-regulation
AGC_DMPK_ROCK_ROCK1_ST	P08670	VIM	Q13464	ROCK1	T32	R36S	36	Missense	distal	4	no	37.377	36.660	EPSD	ICGC;COSMIC	31.796	Down-regulation
AGC_DMPK_ROCK_ROCK1_ST	P08670	VIM	Q13464	ROCK1	S39	R45H	45	Missense	distal	6	no	31.411	32.354	EPSD	ICGC	31.796	Gain
AGC_DMPK_ROCK_ROCK1_ST	P08670	VIM	Q13464	ROCK1	S47	R45H	45	Missense	proximal	-2	no	38.945	27.810	EPSD	ICGC	31.796	Loss
AGC_DMPK_ROCK_ROCK1_ST	P08670	VIM	Q13464	ROCK1	S47	A54G	54	Missense	distal	7	no	38.945	38.913	EPSD	ICGC	31.796	Down-regulation
AGC_DMPK_ROCK_ROCK1_ST	P08670	VIM	Q13464	ROCK1	S55	A54G	54	Missense	proximal	-1	no	30.076	31.887	EPSD	ICGC	31.796	Gain
AGC_DMPK_ROCK_ROCK1_ST	P08670	VIM	Q13464	ROCK1	S56	A54G	54	Missense	proximal	-2	no	27.687	34.858	EPSD	ICGC	31.796	Gain
AGC_DMPK_ROCK_ROCK1_ST	P08670	VIM	Q13464	ROCK1	S278	R273H	273	Missense	distal	-5	no	40.007	38.780	EPSD	ICGC	31.796	Down-regulation
AGC_DMPK_ROCK_ROCK1_ST	P08670	VIM	Q13464	ROCK1	S278	R273G	273	Missense	distal	-5	no	40.007	37.978	EPSD	ICGC	31.796	Down-regulation
AGC_DMPK_ROCK_ROCK1_ST	P08670	VIM	Q13464	ROCK1	S325	S325Y	325	Missense	central	0	yes	33.460	0.000	EPSD	ICGC;COSMIC	31.796	Loss
AGC_DMPK_ROCK_ROCK1_ST	P08670	VIM	Q13464	ROCK1	S325	D331E	331	Missense	distal	6	no	33.460	33.279	EPSD	ICGC;COSMIC	31.796	Down-regulation
AGC_DMPK_ROCK_ROCK1_ST	P08670	VIM	Q13464	ROCK1	S325	V323L	323	Missense	proximal	-2	no	33.460	36.234	EPSD	ICGC;COSMIC	31.796	Up-regulation
AGC_DMPK_ROCK_ROCK1_ST	Q05397	PTK2	Q13464	ROCK1	S517	L511F	511	Missense	distal	-6	no	36.405	35.473	EPSD	ICGC;COSMIC	31.796	Down-regulation
AGC_DMPK_ROCK_ROCK1_ST	Q05397	PTK2	Q13464	ROCK1	S695	R690S	690	Missense	distal	-5	no	36.717	34.444	EPSD	ICGC	31.796	Down-regulation
AGC_DMPK_ROCK_ROCK1_ST	Q05397	PTK2	Q13464	ROCK1	S722	P723Q	723	Missense	proximal	1	no	36.463	36.026	EPSD	ICGC	31.796	Down-regulation
AGC_DMPK_ROCK_ROCK1_ST	Q05397	PTK2	Q13464	ROCK1	S722	E727K	727	Missense	distal	5	no	36.463	35.759	EPSD	ICGC;COSMIC	31.796	Down-regulation
AGC_DMPK_ROCK_ROCK1_ST	Q05397	PTK2	Q13464	ROCK1	S726	P723Q	723	Missense	distal	-3	no	23.296	36.182	EPSD	ICGC	31.796	Gain
AGC_DMPK_ROCK_ROCK1_ST	Q05397	PTK2	Q13464	ROCK1	S732	E727K	727	Missense	distal	-5	no	33.230	35.336	PhosphoSitePlus	ICGC;COSMIC	31.796	Up-regulation
AGC_DMPK_ROCK_ROCK1_ST	Q05397	PTK2	Q13464	ROCK1	S840	L839I	839	Missense	proximal	-1	no	32.355	32.531	EPSD	ICGC	31.796	Up-regulation
AGC_DMPK_ROCK_ROCK1_ST	P48436	SOX9	Q13464	ROCK1	S64	D59E	59	Missense	distal	-5	no	32.369	32.413	EPSD	ICGC;COSMIC	31.796	Up-regulation
AGC_DMPK_ROCK_ROCK1_ST	P48436	SOX9	Q13464	ROCK1	S64	F69C	69	Missense	distal	5	no	32.369	32.107	EPSD	ICGC;COSMIC	31.796	Down-regulation
AGC_DMPK_ROCK_ROCK1_ST	P48436	SOX9	Q13464	ROCK1	S181	E188V	188	Missense	distal	7	no	49.170	49.883	PhosphoSitePlus	ICGC	31.796	Up-regulation
AGC_DMPK_ROCK_ROCK1_ST	P48436	SOX9	Q13464	ROCK1	S181	E188K	188	Missense	distal	7	no	49.170	48.605	PhosphoSitePlus	ICGC	31.796	Down-regulation
AGC_DMPK_ROCK_ROCK1_ST	O14974	PPP1R12A	Q13464	ROCK1	T443	W436L	436	Missense	distal	-7	no	37.502	37.566	EPSD	ICGC;COSMIC	31.796	Up-regulation
AGC_DMPK_ROCK_ROCK1_ST	O14974	PPP1R12A	Q13464	ROCK1	S541	N540Y	540	Missense	proximal	-1	no	33.717	33.672	EPSD	ICGC;COSMIC	31.796	Down-regulation
AGC_DMPK_ROCK_ROCK1_ST	O14974	PPP1R12A	Q13464	ROCK1	S541	S542L	542	Missense	proximal	1	no	33.717	33.968	EPSD	ICGC;COSMIC	31.796	Up-regulation
AGC_DMPK_ROCK_ROCK1_ST	O14974	PPP1R12A	Q13464	ROCK1	S541	L537F	537	Missense	distal	-4	no	33.717	32.502	EPSD	ICGC	31.796	Down-regulation
AGC_DMPK_ROCK_ROCK1_ST	O14974	PPP1R12A	Q13464	ROCK1	S542	N540Y	540	Missense	proximal	-2	no	29.064	34.775	EPSD	ICGC;COSMIC	31.796	Gain
AGC_DMPK_ROCK_ROCK1_ST	O14974	PPP1R12A	Q13464	ROCK1	T593	S591R	591	Missense	proximal	-2	no	27.531	40.531	EPSD	ICGC	31.796	Gain
AGC_DMPK_ROCK_ROCK1_ST	O14974	PPP1R12A	Q13464	ROCK1	S668	R666H	666	Missense	proximal	-2	no	39.953	28.817	EPSD	ICGC;COSMIC	31.796	Loss
AGC_DMPK_ROCK_ROCK1_ST	O14974	PPP1R12A	Q13464	ROCK1	S668	R666C	666	Missense	proximal	-2	no	39.953	7.095	EPSD	ICGC	31.796	Loss
AGC_DMPK_ROCK_ROCK1_ST	O14974	PPP1R12A	Q13464	ROCK1	S852	R850K	850	Missense	proximal	-2	no	43.319	35.568	EPSD;PhosphoSitePlus	ICGC	31.796	Down-regulation
AGC_DMPK_ROCK_ROCK1_ST	O14974	PPP1R12A	Q13464	ROCK1	S852	R845Q	845	Missense	distal	-7	no	43.319	43.236	EPSD;PhosphoSitePlus	ICGC	31.796	Down-regulation
AGC_DMPK_ROCK_ROCK1_ST	O14974	PPP1R12A	Q13464	ROCK1	T853	R850K	850	Missense	distal	-3	no	54.394	50.683	PhosphoSitePlus;EPSD	ICGC	31.796	Down-regulation
AGC_DMPK_ROCK_ROCK1_ST	O14974	PPP1R12A	Q13464	ROCK1	T892	S896L	896	Missense	distal	4	no	40.198	38.905	EPSD	ICGC	31.796	Down-regulation
AGC_DMPK_ROCK_ROCK1_ST	O14974	PPP1R12A	Q13464	ROCK1	S903	S896L	896	Missense	distal	-7	no	33.551	33.564	EPSD	ICGC	31.796	Up-regulation
AGC_DMPK_ROCK_ROCK1_ST	O14974	PPP1R12A	Q13464	ROCK1	S903	R907H	907	Missense	distal	4	no	33.551	32.963	EPSD	ICGC;COSMIC	31.796	Down-regulation
AGC_DMPK_ROCK_ROCK1_ST	O14974	PPP1R12A	Q13464	ROCK1	S903	G909R	909	Missense	distal	6	no	33.551	32.477	EPSD	ICGC;COSMIC	31.796	Down-regulation
AGC_DMPK_ROCK_ROCK1_ST	Q9UPT6	MAPK8IP3	Q13464	ROCK1	T169	E170Q	170	Missense	proximal	1	no	32.946	32.534	EPSD	ICGC;COSMIC	31.796	Down-regulation
AGC_DMPK_ROCK_ROCK1_ST	Q9UPT6	MAPK8IP3	Q13464	ROCK1	T275	T275M	275	Missense	central	0	yes	35.212	0.000	EPSD	ICGC;COSMIC	31.796	Loss
AGC_DMPK_ROCK_ROCK1_ST	Q9UPT6	MAPK8IP3	Q13464	ROCK1	T277	T275M	275	Missense	proximal	-2	no	27.522	33.032	EPSD	ICGC;COSMIC	31.796	Gain
AGC_DMPK_ROCK_ROCK1_ST	Q9UPT6	MAPK8IP3	Q13464	ROCK1	S314	A308S	308	Missense	distal	-6	no	41.971	42.233	PhosphoSitePlus;EPSD	ICGC	31.796	Up-regulation
AGC_DMPK_ROCK_ROCK1_ST	Q9UPT6	MAPK8IP3	Q13464	ROCK1	S314	D313Y	313	Missense	proximal	-1	no	41.971	43.364	PhosphoSitePlus;EPSD	ICGC;COSMIC	31.796	Up-regulation
AGC_DMPK_ROCK_ROCK1_ST	Q9UPT6	MAPK8IP3	Q13464	ROCK1	S364	R358S	358	Missense	distal	-6	no	37.309	34.701	EPSD;PhosphoSitePlus	ICGC;COSMIC	31.796	Down-regulation
AGC_DMPK_ROCK_ROCK1_ST	Q9UPT6	MAPK8IP3	Q13464	ROCK1	S365	R358S	358	Missense	distal	-7	no	34.517	34.323	EPSD;PhosphoSitePlus	ICGC;COSMIC	31.796	Down-regulation
AGC_DMPK_ROCK_ROCK1_ST	Q9UPT6	MAPK8IP3	Q13464	ROCK1	T552	R550Q	550	Missense	proximal	-2	no	38.740	25.570	EPSD	ICGC;COSMIC	31.796	Loss
AGC_DMPK_ROCK_ROCK1_ST	Q9UPT6	MAPK8IP3	Q13464	ROCK1	T552	E547D	547	Missense	distal	-5	no	38.740	38.695	EPSD	ICGC;COSMIC	31.796	Down-regulation
AGC_DMPK_ROCK_ROCK1_ST	Q9UPT6	MAPK8IP3	Q13464	ROCK1	S1191	G1195W	1195	Missense	distal	4	no	33.950	32.930	EPSD	ICGC;COSMIC	31.796	Down-regulation
AGC_PKG_PRKG2_ST	P29474	NOS3	Q13237	PRKG2	S114	K108I	108	Missense	distal	-6	no	57.772	55.793	EPSD	ICGC;COSMIC	42.682	Down-regulation
AGC_PKG_PRKG2_ST	P29474	NOS3	Q13237	PRKG2	S114	P120S	120	Missense	distal	6	no	57.772	57.055	EPSD	ICGC	42.682	Down-regulation
AGC_PKG_PRKG2_ST	P29474	NOS3	Q13237	PRKG2	S114	Q110L	110	Missense	distal	-4	no	57.772	57.080	EPSD	ICGC;COSMIC	42.682	Down-regulation
AGC_PKG_PRKG2_ST	P29474	NOS3	Q13237	PRKG2	T495	A500S	500	Missense	distal	5	no	68.880	68.823	PhosphoSitePlus;EPSD	ICGC	42.682	Down-regulation
AGC_PKG_PRKG2_ST	P29474	NOS3	Q13237	PRKG2	T495	A502S	502	Missense	distal	7	no	68.880	69.844	PhosphoSitePlus;EPSD	ICGC	42.682	Up-regulation
AGC_PKG_PRKG2_ST	P29474	NOS3	Q13237	PRKG2	T495	K493N	493	Missense	proximal	-2	no	68.880	59.800	PhosphoSitePlus;EPSD	ICGC;COSMIC	42.682	Down-regulation
AGC_PKG_PRKG2_ST	P29474	NOS3	Q13237	PRKG2	S615	S617P	617	Missense	proximal	2	no	44.807	44.943	EPSD	ICGC;COSMIC	42.682	Up-regulation
AGC_PKG_PRKG2_ST	P29474	NOS3	Q13237	PRKG2	S615	S608I	608	Missense	distal	-7	no	44.807	47.322	EPSD	ICGC	42.682	Up-regulation
AGC_PKG_PRKG2_ST	P29474	NOS3	Q13237	PRKG2	S615	P621T	621	Missense	distal	6	no	44.807	44.438	EPSD	ICGC;COSMIC	42.682	Down-regulation
AGC_PKG_PRKG2_ST	P29474	NOS3	Q13237	PRKG2	S633	R627W	627	Missense	distal	-6	no	74.934	73.894	EPSD;PhosphoSitePlus	ICGC;COSMIC	42.682	Down-regulation
AGC_PKG_PRKG2_ST	P29474	NOS3	Q13237	PRKG2	S633	R628W	628	Missense	distal	-5	no	74.934	74.958	EPSD;PhosphoSitePlus	ICGC;COSMIC	42.682	Up-regulation
AGC_PKG_PRKG2_ST	P29474	NOS3	Q13237	PRKG2	S1177	Q1184H	1184	Missense	distal	7	no	74.260	73.693	EPSD;PhosphoSitePlus	ICGC;COSMIC	42.682	Down-regulation
AGC_PKG_PRKG2_ST	P29474	NOS3	Q13237	PRKG2	S1177	Q1176E	1176	Missense	proximal	-1	no	74.260	74.432	EPSD;PhosphoSitePlus	ICGC;COSMIC	42.682	Up-regulation
AGC_PKG_PRKG2_ST	P09619	PDGFRB	Q13237	PRKG2	S643	S638T	638	Missense	distal	-5	no	63.535	63.544	EPSD	ICGC;COSMIC	42.682	Up-regulation
AGC_PKG_PRKG2_ST	P09619	PDGFRB	Q13237	PRKG2	S643	Q646K	646	Missense	distal	3	no	63.535	63.960	EPSD	ICGC;COSMIC	42.682	Up-regulation
AGC_PKG_PRKG2_ST	P09619	PDGFRB	Q13237	PRKG2	S705	P710Q	710	Missense	distal	5	no	53.834	53.832	EPSD	ICGC	42.682	Down-regulation
AGC_PKG_PRKG2_ST	P09619	PDGFRB	Q13237	PRKG2	S705	Q702K	702	Missense	distal	-3	no	53.834	58.629	EPSD	ICGC	42.682	Up-regulation
AGC_PKG_PRKG2_ST	P09619	PDGFRB	Q13237	PRKG2	S712	P710Q	710	Missense	proximal	-2	no	37.989	52.035	PhosphoSitePlus	ICGC	42.682	Gain
AGC_PKG_PRKG2_ST	P09619	PDGFRB	Q13237	PRKG2	S930	H928R	928	Missense	proximal	-2	no	30.296	45.535	EPSD	ICGC;COSMIC	42.682	Gain
AGC_PKG_PRKG2_ST	Q14847	LASP1	Q13237	PRKG2	S146	M139I	139	Missense	distal	-7	no	70.509	71.664	PhosphoSitePlus	ICGC;COSMIC	42.682	Up-regulation
AGC_PKG_PRKG2_ST	P08581	MET	Q13237	PRKG2	S758	G764R	764	Missense	distal	6	no	44.324	43.965	EPSD	ICGC;COSMIC	42.682	Down-regulation
AGC_PKG_PRKG2_ST	P08581	MET	Q13237	PRKG2	S758	G756V	756	Missense	proximal	-2	no	44.324	20.473	EPSD	ICGC	42.682	Loss
AGC_PKG_PRKG2_ST	P08581	MET	Q13237	PRKG2	S985	R987G	987	Missense	proximal	2	no	69.823	70.075	PhosphoSitePlus	ICGC;COSMIC	42.682	Up-regulation
AGC_PKG_PRKG2_ST	P08581	MET	Q13237	PRKG2	S985	L983H	983	Missense	proximal	-2	no	69.823	66.662	PhosphoSitePlus	ICGC;COSMIC	42.682	Down-regulation
AGC_PKG_PRKG2_ST	P08581	MET	Q13237	PRKG2	S985	H979Y	979	Missense	distal	-6	no	69.823	72.421	PhosphoSitePlus	ICGC;COSMIC	42.682	Up-regulation
AGC_PKG_PRKG2_ST	P08581	MET	Q13237	PRKG2	S985	R982M	982	Missense	distal	-3	no	69.823	36.891	PhosphoSitePlus	ICGC;COSMIC	42.682	Loss
AGC_PKG_PRKG2_ST	P08581	MET	Q13237	PRKG2	S988	M995I	995	Missense	distal	7	no	47.275	47.364	EPSD	ICGC;COSMIC	42.682	Up-regulation
AGC_PKG_PRKG2_ST	P08581	MET	Q13237	PRKG2	S988	R987G	987	Missense	proximal	-1	no	47.275	47.639	EPSD	ICGC;COSMIC	42.682	Up-regulation
AGC_PKG_PRKG2_ST	P08581	MET	Q13237	PRKG2	S988	L983H	983	Missense	distal	-5	no	47.275	47.280	EPSD	ICGC;COSMIC	42.682	Up-regulation
AGC_PKG_PRKG2_ST	P08581	MET	Q13237	PRKG2	S988	E994K	994	Missense	distal	6	no	47.275	46.791	EPSD	ICGC;COSMIC	42.682	Down-regulation
AGC_PKG_PRKG2_ST	P08581	MET	Q13237	PRKG2	S988	R982M	982	Missense	distal	-6	no	47.275	46.344	EPSD	ICGC;COSMIC	42.682	Down-regulation
AGC_PKG_PRKG2_ST	P08581	MET	Q13237	PRKG2	S990	M995I	995	Missense	distal	5	no	44.688	44.663	EPSD	ICGC;COSMIC	42.682	Down-regulation
AGC_PKG_PRKG2_ST	P08581	MET	Q13237	PRKG2	S990	R987G	987	Missense	distal	-3	no	44.688	25.705	EPSD	ICGC;COSMIC	42.682	Loss
AGC_PKG_PRKG2_ST	P08581	MET	Q13237	PRKG2	S990	L983H	983	Missense	distal	-7	no	44.688	45.336	EPSD	ICGC;COSMIC	42.682	Up-regulation
AGC_PKG_PRKG2_ST	P08581	MET	Q13237	PRKG2	S990	E994K	994	Missense	distal	4	no	44.688	43.818	EPSD	ICGC;COSMIC	42.682	Down-regulation
AGC_PKG_PRKG2_ST	P08581	MET	Q13237	PRKG2	S990	V996I	996	Missense	distal	6	no	44.688	45.048	EPSD	ICGC;COSMIC	42.682	Up-regulation
AGC_PKG_PRKG2_ST	P08581	MET	Q13237	PRKG2	S1016	P1013S	1013	Missense	distal	-3	no	39.369	46.717	EPSD	ICGC;COSMIC	42.682	Gain
AGC_PKG_PRKG2_ST	P08581	MET	Q13237	PRKG2	S1020	V1024L	1024	Missense	distal	4	no	50.309	47.058	EPSD	ICGC;COSMIC	42.682	Down-regulation
AGC_PKG_PRKG2_ST	P08581	MET	Q13237	PRKG2	S1020	Q1025L	1025	Missense	distal	5	no	50.309	50.028	EPSD	ICGC;COSMIC	42.682	Down-regulation
AGC_PKG_PRKG2_ST	P08581	MET	Q13237	PRKG2	S1020	N1014S	1014	Missense	distal	-6	no	50.309	52.641	EPSD	ICGC;COSMIC	42.682	Up-regulation
AGC_PKG_PRKG2_ST	P08581	MET	Q13237	PRKG2	S1020	P1013S	1013	Missense	distal	-7	no	50.309	49.996	EPSD	ICGC;COSMIC	42.682	Down-regulation
AGC_PKG_PRKG2_ST	P08581	MET	Q13237	PRKG2	S1338	A1339V	1339	Missense	proximal	1	no	57.530	58.363	EPSD	ICGC;COSMIC	42.682	Up-regulation
AGC_PKG_PRKG2_ST	P08581	MET	Q13237	PRKG2	S1338	R1336W	1336	Missense	proximal	-2	no	57.530	24.181	EPSD	ICGC;COSMIC	42.682	Loss
TK_Fer_FER_Y	P15311	EZR	P16591	FER	Y146	H142Q	142	Missense	distal	-4	no	0.177	0.175	EPSD;PhosphoSitePlus	ICGC;COSMIC	0.101	Down-regulation
TK_Fer_FER_Y	P15311	EZR	P16591	FER	Y146	H142N	142	Missense	distal	-4	no	0.177	0.170	EPSD;PhosphoSitePlus	ICGC;COSMIC	0.101	Down-regulation
TK_Fer_FER_Y	P15311	EZR	P16591	FER	Y354	A361E	361	Missense	distal	7	no	0.173	0.179	EPSD;PhosphoSitePlus	ICGC	0.101	Up-regulation
TK_Fer_FER_Y	P15311	EZR	P16591	FER	Y424	L421I	421	Missense	distal	-3	no	0.099	0.102	EPSD	ICGC	0.101	Gain
TK_Fer_FER_Y	P15311	EZR	P16591	FER	Y478	P471L	471	Missense	distal	-7	no	0.203	0.191	PhosphoSitePlus;EPSD	ICGC;COSMIC;GDSC	0.101	Down-regulation
TK_Fer_FER_Y	P08581	MET	P16591	FER	Y1194	F1200I	1200	Missense	distal	6	no	0.090	0.108	EPSD	ICGC;COSMIC	0.101	Gain
TK_Fer_FER_Y	P08581	MET	P16591	FER	Y1235	Y1230H	1230	Missense	distal	-5	no	0.102	0.116	EPSD	ICGC;COSMIC	0.101	Up-regulation
TK_Fer_FER_Y	P08581	MET	P16591	FER	Y1235	Y1230C	1230	Missense	distal	-5	no	0.102	0.122	EPSD	ICGC;COSMIC	0.101	Up-regulation
TK_Fer_FER_Y	P08581	MET	P16591	FER	Y1235	D1228H	1228	Missense	distal	-7	no	0.102	0.094	EPSD	ICGC;COSMIC	0.101	Loss
TK_Fer_FER_Y	P08581	MET	P16591	FER	Y1235	S1236R	1236	Missense	proximal	1	no	0.102	0.072	EPSD	ICGC;COSMIC	0.101	Loss
TK_Fer_FER_Y	P08581	MET	P16591	FER	Y1235	G1242V	1242	Missense	distal	7	no	0.102	0.105	EPSD	ICGC	0.101	Up-regulation
TK_Fer_FER_Y	P08581	MET	P16591	FER	Y1235	H1238L	1238	Missense	distal	3	no	0.102	0.104	EPSD	ICGC;COSMIC	0.101	Up-regulation
TK_Fer_FER_Y	P08581	MET	P16591	FER	Y1235	Y1235H	1235	Missense	central	0	yes	0.102	0.000	EPSD	ICGC;COSMIC	0.101	Loss
TK_Fer_FER_Y	P08581	MET	P16591	FER	Y1235	D1228Y	1228	Missense	distal	-7	no	0.102	0.091	EPSD	ICGC	0.101	Loss
TK_Fer_FER_Y	P08581	MET	P16591	FER	Y1235	D1228A	1228	Missense	distal	-7	no	0.102	0.099	EPSD	ICGC	0.101	Loss
TK_Fer_FER_Y	P08581	MET	P16591	FER	Y1349	V1352L	1352	Missense	distal	3	no	0.204	0.205	PhosphoSitePlus	ICGC;COSMIC	0.101	Up-regulation
TK_Fer_FER_Y	P08581	MET	P16591	FER	Y1349	H1351Y	1351	Missense	proximal	2	no	0.204	0.209	PhosphoSitePlus	ICGC;COSMIC	0.101	Up-regulation
TK_Fer_FER_Y	P08581	MET	P16591	FER	Y1349	Y1356C	1356	Missense	distal	7	no	0.204	0.193	PhosphoSitePlus	ICGC;COSMIC	0.101	Down-regulation
TK_Fer_FER_Y	P10275	AR	P16591	FER	Y225	P218S	218	Missense	distal	-7	no	0.181	0.182	PhosphoSitePlus	ICGC	0.101	Up-regulation
TK_Fer_FER_Y	P10275	AR	P16591	FER	Y225	P218L	218	Missense	distal	-7	no	0.181	0.169	PhosphoSitePlus	ICGC	0.101	Down-regulation
TK_Fer_FER_Y	P10275	AR	P16591	FER	Y552	P556S	556	Missense	distal	4	no	0.088	0.102	EPSD	ICGC;COSMIC	0.101	Gain
TK_Fer_FER_Y	P40763	STAT3	P16591	FER	Y674	V667L	667	Missense	distal	-7	no	0.132	0.133	EPSD	ICGC	0.101	Up-regulation
TK_Fer_FER_Y	P40763	STAT3	P16591	FER	Y674	S668F	668	Missense	distal	-6	no	0.132	0.127	EPSD	ICGC	0.101	Down-regulation
TK_Fer_FER_Y	P40763	STAT3	P16591	FER	Y705	A702T	702	Missense	distal	-3	no	0.182	0.187	PhosphoSitePlus	ICGC;COSMIC	0.101	Up-regulation
TK_Fer_FER_Y	P16591	FER	P16591	FER	Y229	S234I	234	Missense	distal	5	no	0.133	0.130	EPSD	ICGC	0.101	Down-regulation
TK_Fer_FER_Y	P16591	FER	P16591	FER	Y615	E608K	608	Missense	distal	-7	no	0.186	0.184	EPSD;PhosphoSitePlus	ICGC;COSMIC	0.101	Down-regulation
TK_Fer_FER_Y	P16591	FER	P16591	FER	Y714	D710Y	710	Missense	distal	-4	no	0.205	0.188	PhosphoSitePlus;EPSD	ICGC	0.101	Down-regulation
TK_Fer_FER_Y	P14923	JUP	P16591	FER	Y550	T546I	546	Missense	distal	-4	no	0.211	0.195	PhosphoSitePlus	ICGC	0.101	Down-regulation
TK_Fer_FER_Y	P14923	JUP	P16591	FER	Y550	Q547H	547	Missense	distal	-3	no	0.211	0.202	PhosphoSitePlus	ICGC	0.101	Down-regulation
CMGC_CDK_CDK9_CDK9_ST	O00267	SUPT5H	P50750	CDK9	S108	V113F	113	Missense	distal	5	no	2.024	1.974	EPSD	ICGC	1.932	Down-regulation
CMGC_CDK_CDK9_CDK9_ST	O00267	SUPT5H	P50750	CDK9	S108	V114F	114	Missense	distal	6	no	2.024	1.924	EPSD	ICGC	1.932	Loss
CMGC_CDK_CDK9_CDK9_ST	O00267	SUPT5H	P50750	CDK9	T166	D164N	164	Missense	proximal	-2	no	2.234	2.567	EPSD	ICGC;COSMIC	1.932	Up-regulation
CMGC_CDK_CDK9_CDK9_ST	O00267	SUPT5H	P50750	CDK9	T655	R652H	652	Missense	distal	-3	no	2.325	2.329	EPSD	ICGC;COSMIC	1.932	Up-regulation
CMGC_CDK_CDK9_CDK9_ST	O00267	SUPT5H	P50750	CDK9	T655	G648V	648	Missense	distal	-7	no	2.325	2.326	EPSD	ICGC	1.932	Up-regulation
CMGC_CDK_CDK9_CDK9_ST	O00267	SUPT5H	P50750	CDK9	S666	A663V	663	Missense	distal	-3	no	6.182	6.174	EPSD;PhosphoSitePlus	ICGC;COSMIC	1.932	Down-regulation
CMGC_CDK_CDK9_CDK9_ST	O00267	SUPT5H	P50750	CDK9	S666	P667L	667	Missense	proximal	1	no	6.182	0.584	EPSD;PhosphoSitePlus	ICGC;COSMIC	1.932	Loss
CMGC_CDK_CDK9_CDK9_ST	O00267	SUPT5H	P50750	CDK9	S671	P667L	667	Missense	distal	-4	no	5.138	5.004	EPSD	ICGC;COSMIC	1.932	Down-regulation
CMGC_CDK_CDK9_CDK9_ST	O00267	SUPT5H	P50750	CDK9	S686	G692C	692	Missense	distal	6	no	4.609	4.448	EPSD	ICGC	1.932	Down-regulation
CMGC_CDK_CDK9_CDK9_ST	O00267	SUPT5H	P50750	CDK9	S686	G690S	690	Missense	distal	4	no	4.609	4.708	EPSD	ICGC	1.932	Up-regulation
CMGC_CDK_CDK9_CDK9_ST	O00267	SUPT5H	P50750	CDK9	S686	P687T	687	Missense	proximal	1	no	4.609	0.590	EPSD	ICGC;COSMIC	1.932	Loss
CMGC_CDK_CDK9_CDK9_ST	O00267	SUPT5H	P50750	CDK9	T768	S763A	763	Missense	distal	-5	no	5.825	5.407	EPSD;PhosphoSitePlus	ICGC;COSMIC	1.932	Down-regulation
CMGC_CDK_CDK9_CDK9_ST	O00267	SUPT5H	P50750	CDK9	T768	M761I	761	Missense	distal	-7	no	5.825	5.834	EPSD;PhosphoSitePlus	ICGC;GDSC;CCLE	1.932	Up-regulation
CMGC_CDK_CDK9_CDK9_ST	O00267	SUPT5H	P50750	CDK9	T775	M777I	777	Missense	proximal	2	no	5.410	5.433	EPSD;PhosphoSitePlus	ICGC;COSMIC	1.932	Up-regulation
CMGC_CDK_CDK9_CDK9_ST	O00267	SUPT5H	P50750	CDK9	T775	G781V	781	Missense	distal	6	no	5.410	5.366	EPSD;PhosphoSitePlus	ICGC;COSMIC	1.932	Down-regulation
CMGC_CDK_CDK9_CDK9_ST	O00267	SUPT5H	P50750	CDK9	T784	M777I	777	Missense	distal	-7	no	5.620	5.629	EPSD;PhosphoSitePlus	ICGC;COSMIC	1.932	Up-regulation
CMGC_CDK_CDK9_CDK9_ST	O00267	SUPT5H	P50750	CDK9	T784	G781V	781	Missense	distal	-3	no	5.620	5.618	EPSD;PhosphoSitePlus	ICGC;COSMIC	1.932	Down-regulation
CMGC_CDK_CDK9_CDK9_ST	O00267	SUPT5H	P50750	CDK9	T784	R783Q	783	Missense	proximal	-1	no	5.620	5.638	EPSD;PhosphoSitePlus	ICGC;COSMIC	1.932	Up-regulation
CMGC_CDK_CDK9_CDK9_ST	O00267	SUPT5H	P50750	CDK9	T791	R798C	798	Missense	distal	7	no	6.618	6.723	EPSD;PhosphoSitePlus	ICGC;COSMIC	1.932	Up-regulation
CMGC_CDK_CDK9_CDK9_ST	O00267	SUPT5H	P50750	CDK9	T799	T806M	806	Missense	distal	7	no	4.553	4.600	EPSD;PhosphoSitePlus	ICGC	1.932	Up-regulation
CMGC_CDK_CDK9_CDK9_ST	O00267	SUPT5H	P50750	CDK9	T799	R798C	798	Missense	proximal	-1	no	4.553	4.528	EPSD;PhosphoSitePlus	ICGC;COSMIC	1.932	Down-regulation
CMGC_CDK_CDK9_CDK9_ST	O00267	SUPT5H	P50750	CDK9	T799	L793F	793	Missense	distal	-6	no	4.553	4.572	EPSD;PhosphoSitePlus	ICGC;COSMIC	1.932	Up-regulation
CMGC_CDK_CDK9_CDK9_ST	O00267	SUPT5H	P50750	CDK9	T799	G803D	803	Missense	distal	4	no	4.553	4.506	EPSD;PhosphoSitePlus	ICGC	1.932	Down-regulation
CMGC_CDK_CDK9_CDK9_ST	O00267	SUPT5H	P50750	CDK9	T806	T806M	806	Missense	central	0	yes	5.999	0.000	EPSD;PhosphoSitePlus	ICGC	1.932	Loss
CMGC_CDK_CDK9_CDK9_ST	O00267	SUPT5H	P50750	CDK9	T806	G803D	803	Missense	distal	-3	no	5.999	6.001	EPSD;PhosphoSitePlus	ICGC	1.932	Up-regulation
CMGC_CDK_CDK9_CDK9_ST	O00267	SUPT5H	P50750	CDK9	S812	T814I	814	Missense	proximal	2	no	2.029	2.095	EPSD	ICGC;COSMIC	1.932	Up-regulation
CMGC_CDK_CDK9_CDK9_ST	O00267	SUPT5H	P50750	CDK9	S812	T806M	806	Missense	distal	-6	no	2.029	1.921	EPSD	ICGC	1.932	Loss
CMGC_CDK_CDK9_CDK9_ST	O00267	SUPT5H	P50750	CDK9	S812	P815F	815	Missense	distal	3	no	2.029	1.691	EPSD	ICGC	1.932	Loss
CMGC_CDK_CDK9_CDK9_ST	O00267	SUPT5H	P50750	CDK9	T814	T814I	814	Missense	central	0	yes	6.210	0.000	PhosphoSitePlus;EPSD	ICGC;COSMIC	1.932	Loss
CMGC_CDK_CDK9_CDK9_ST	O00267	SUPT5H	P50750	CDK9	T814	P815F	815	Missense	proximal	1	no	6.210	1.173	PhosphoSitePlus;EPSD	ICGC	1.932	Loss
CMGC_CDK_CDK9_CDK9_ST	O00267	SUPT5H	P50750	CDK9	T828	P829L	829	Missense	proximal	1	no	4.793	-0.805	EPSD	ICGC	1.932	Loss
CMGC_CDK_CDK9_CDK9_ST	O00267	SUPT5H	P50750	CDK9	T828	P823H	823	Missense	distal	-5	no	4.793	4.518	EPSD	ICGC;COSMIC	1.932	Down-regulation
CMGC_CDK_CDK9_CDK9_ST	O00267	SUPT5H	P50750	CDK9	T854	P857H	857	Missense	distal	3	no	6.761	6.513	EPSD	ICGC;COSMIC	1.932	Down-regulation
CMGC_CDK_CDK9_CDK9_ST	O00267	SUPT5H	P50750	CDK9	T859	P865H	865	Missense	distal	6	no	5.525	5.048	EPSD	ICGC;COSMIC	1.932	Down-regulation
CMGC_CDK_CDK9_CDK9_ST	O00267	SUPT5H	P50750	CDK9	T859	P857H	857	Missense	proximal	-2	no	5.525	4.897	EPSD	ICGC;COSMIC	1.932	Down-regulation
CMGC_CDK_CDK9_CDK9_ST	O00267	SUPT5H	P50750	CDK9	S866	S867P	867	Missense	proximal	1	no	1.725	5.459	EPSD	ICGC;COSMIC	1.932	Gain
CMGC_CDK_CDK9_CDK9_ST	O00267	SUPT5H	P50750	CDK9	S867	S867P	867	Missense	central	0	yes	5.181	0.000	EPSD	ICGC;COSMIC	1.932	Loss
CMGC_CDK_CDK9_CDK9_ST	O00267	SUPT5H	P50750	CDK9	S867	P865H	865	Missense	proximal	-2	no	5.181	4.553	EPSD	ICGC;COSMIC	1.932	Down-regulation
CMGC_CDK_CDK9_CDK9_ST	O00267	SUPT5H	P50750	CDK9	T878	T881M	881	Missense	distal	3	no	4.472	4.421	EPSD	ICGC	1.932	Down-regulation
CMGC_CDK_CDK9_CDK9_ST	O00267	SUPT5H	P50750	CDK9	T878	G880W	880	Missense	proximal	2	no	4.472	4.496	EPSD	ICGC;COSMIC	1.932	Up-regulation
CMGC_CDK_CDK9_CDK9_ST	O00267	SUPT5H	P50750	CDK9	T878	P876S	876	Missense	proximal	-2	no	4.472	4.233	EPSD	ICGC	1.932	Down-regulation
CMGC_CDK_CDK9_CDK9_ST	O00267	SUPT5H	P50750	CDK9	T881	T881M	881	Missense	central	0	yes	4.187	0.000	EPSD	ICGC	1.932	Loss
CMGC_CDK_CDK9_CDK9_ST	O00267	SUPT5H	P50750	CDK9	T881	G880W	880	Missense	proximal	-1	no	4.187	4.171	EPSD	ICGC;COSMIC	1.932	Down-regulation
CMGC_CDK_CDK9_CDK9_ST	O00267	SUPT5H	P50750	CDK9	T881	P876S	876	Missense	distal	-5	no	4.187	4.273	EPSD	ICGC	1.932	Up-regulation
CMGC_CDK_CDK9_CDK9_ST	O00267	SUPT5H	P50750	CDK9	S897	P904A	904	Missense	distal	7	no	4.658	4.919	EPSD	ICGC;COSMIC	1.932	Up-regulation
CMGC_CDK_CDK9_CDK9_ST	O00267	SUPT5H	P50750	CDK9	S897	P898T	898	Missense	proximal	1	no	4.658	0.639	EPSD	ICGC;COSMIC	1.932	Loss
CMGC_CDK_CDK9_CDK9_ST	O00267	SUPT5H	P50750	CDK9	S951	M953V	953	Missense	proximal	2	no	5.788	5.795	EPSD	ICGC	1.932	Up-regulation
CMGC_CDK_CDK9_CDK9_ST	O00267	SUPT5H	P50750	CDK9	S951	S946G	946	Missense	distal	-5	no	5.788	5.425	EPSD	ICGC	1.932	Down-regulation
CMGC_CDK_CDK9_CDK9_ST	O00267	SUPT5H	P50750	CDK9	T954	M953V	953	Missense	proximal	-1	no	5.814	5.802	EPSD	ICGC	1.932	Down-regulation
CMGC_CDK_CDK9_CDK9_ST	O00267	SUPT5H	P50750	CDK9	S959	M953V	953	Missense	distal	-6	no	5.389	5.372	EPSD	ICGC	1.932	Down-regulation
CMGC_CDK_CDK9_CDK9_ST	O00267	SUPT5H	P50750	CDK9	T967	P968S	968	Missense	proximal	1	no	5.577	1.843	EPSD	ICGC;GDSC;CCLE	1.932	Loss
CMGC_CDK_CDK9_CDK9_ST	O00267	SUPT5H	P50750	CDK9	T1034	P1035H	1035	Missense	proximal	1	no	5.754	1.180	EPSD	ICGC;COSMIC	1.932	Loss
CMGC_CDK_CDK9_CDK9_ST	O00267	SUPT5H	P50750	CDK9	T1034	P1035T	1035	Missense	proximal	1	no	5.754	1.735	EPSD	ICGC;COSMIC	1.932	Loss
CMGC_CDK_CDK9_CDK9_ST	Q15797	SMAD1	P50750	CDK9	T10	S8F	8	Missense	proximal	-2	no	2.283	1.764	EPSD	ICGC	1.932	Loss
CMGC_CDK_CDK9_CDK9_ST	Q15797	SMAD1	P50750	CDK9	T10	S5R	5	Missense	distal	-5	no	2.283	1.954	EPSD	ICGC	1.932	Down-regulation
CMGC_CDK_CDK9_CDK9_ST	Q15797	SMAD1	P50750	CDK9	S11	S8F	8	Missense	distal	-3	no	4.480	4.571	EPSD	ICGC	1.932	Up-regulation
CMGC_CDK_CDK9_CDK9_ST	Q15797	SMAD1	P50750	CDK9	S11	S5R	5	Missense	distal	-6	no	4.480	4.192	EPSD	ICGC	1.932	Down-regulation
CMGC_CDK_CDK9_CDK9_ST	Q15797	SMAD1	P50750	CDK9	S11	L18I	18	Missense	distal	7	no	4.480	4.467	EPSD	ICGC;COSMIC	1.932	Down-regulation
CMGC_CDK_CDK9_CDK9_ST	Q15797	SMAD1	P50750	CDK9	S187	N180H	180	Missense	distal	-7	no	5.904	5.927	EPSD;PhosphoSitePlus	ICGC;COSMIC	1.932	Up-regulation
CMGC_CDK_CDK9_CDK9_ST	Q15797	SMAD1	P50750	CDK9	S187	P188T	188	Missense	proximal	1	no	5.904	1.885	EPSD;PhosphoSitePlus	ICGC;COSMIC	1.932	Loss
CMGC_CDK_CDK9_CDK9_ST	Q15797	SMAD1	P50750	CDK9	S187	P183S	183	Missense	distal	-4	no	5.904	5.924	EPSD;PhosphoSitePlus	ICGC	1.932	Up-regulation
CMGC_CDK_CDK9_CDK9_ST	Q15797	SMAD1	P50750	CDK9	S195	T202A	202	Missense	distal	7	no	7.020	7.125	PhosphoSitePlus;EPSD	ICGC;COSMIC	1.932	Up-regulation
CMGC_CDK_CDK9_CDK9_ST	Q15797	SMAD1	P50750	CDK9	S195	G197W	197	Missense	proximal	2	no	7.020	7.045	PhosphoSitePlus;EPSD	ICGC;COSMIC	1.932	Up-regulation
CMGC_CDK_CDK9_CDK9_ST	Q15797	SMAD1	P50750	CDK9	S195	P188T	188	Missense	distal	-7	no	7.020	7.060	PhosphoSitePlus;EPSD	ICGC;COSMIC	1.932	Up-regulation
CMGC_CDK_CDK9_CDK9_ST	Q15797	SMAD1	P50750	CDK9	S206	T202A	202	Missense	distal	-4	no	6.575	6.525	EPSD;PhosphoSitePlus	ICGC;COSMIC	1.932	Down-regulation
CMGC_CDK_CDK9_CDK9_ST	Q15797	SMAD1	P50750	CDK9	S315	R319W	319	Missense	distal	4	no	2.576	2.540	EPSD	ICGC;COSMIC	1.932	Down-regulation
CMGC_CDK_CDK9_CDK9_ST	Q15797	SMAD1	P50750	CDK9	S315	G312W	312	Missense	distal	-3	no	2.576	2.585	EPSD	ICGC	1.932	Up-regulation
CMGC_CDK_CDK9_CDK9_ST	Q15797	SMAD1	P50750	CDK9	S456	P457L	457	Missense	proximal	1	no	5.636	0.037	EPSD	ICGC;COSMIC	1.932	Loss
CMGC_CDK_CDK9_CDK9_ST	Q15797	SMAD1	P50750	CDK9	S462	P457L	457	Missense	distal	-5	no	2.834	2.454	EPSD	ICGC;COSMIC	1.932	Down-regulation
CMGC_CDK_CDK9_CDK9_ST	P50750	CDK9	P50750	CDK9	S90	R94C	94	Missense	distal	4	no	3.904	3.863	EPSD	ICGC;COSMIC	1.932	Down-regulation
CMGC_CDK_CDK9_CDK9_ST	P50750	CDK9	P50750	CDK9	S90	R86L	86	Missense	distal	-4	no	3.904	3.865	EPSD	ICGC	1.932	Down-regulation
CMGC_CDK_CDK9_CDK9_ST	P50750	CDK9	P50750	CDK9	S90	C95F	95	Missense	distal	5	no	3.904	3.907	EPSD	ICGC	1.932	Up-regulation
CMGC_CDK_CDK9_CDK9_ST	P50750	CDK9	P50750	CDK9	S90	R94H	94	Missense	distal	4	no	3.904	3.895	EPSD	ICGC;COSMIC	1.932	Down-regulation
CMGC_CDK_CDK9_CDK9_ST	P50750	CDK9	P50750	CDK9	T186	P182S	182	Missense	distal	-4	no	2.467	2.488	PhosphoSitePlus;EPSD	ICGC;COSMIC	1.932	Up-regulation
CMGC_CDK_CDK9_CDK9_ST	P50750	CDK9	P50750	CDK9	T186	N183K	183	Missense	distal	-3	no	2.467	2.484	PhosphoSitePlus;EPSD	ICGC;COSMIC	1.932	Up-regulation
CMGC_CDK_CDK9_CDK9_ST	P50750	CDK9	P50750	CDK9	T186	R184H	184	Missense	proximal	-2	no	2.467	2.396	PhosphoSitePlus;EPSD	ICGC	1.932	Down-regulation
CMGC_CDK_CDK9_CDK9_ST	P50750	CDK9	P50750	CDK9	S347	Q351H	351	Missense	distal	4	no	3.411	3.350	EPSD;PhosphoSitePlus	ICGC;COSMIC	1.932	Down-regulation
CMGC_CDK_CDK9_CDK9_ST	P50750	CDK9	P50750	CDK9	S347	Q348H	348	Missense	proximal	1	no	3.411	2.392	EPSD;PhosphoSitePlus	ICGC	1.932	Down-regulation
CMGC_CDK_CDK9_CDK9_ST	P50750	CDK9	P50750	CDK9	T350	N355S	355	Missense	distal	5	no	3.328	3.548	EPSD	ICGC	1.932	Up-regulation
CMGC_CDK_CDK9_CDK9_ST	P50750	CDK9	P50750	CDK9	T350	Q351H	351	Missense	proximal	1	no	3.328	2.309	EPSD	ICGC;COSMIC	1.932	Down-regulation
CMGC_CDK_CDK9_CDK9_ST	P50750	CDK9	P50750	CDK9	T350	Q348H	348	Missense	proximal	-2	no	3.328	3.050	EPSD	ICGC	1.932	Down-regulation
CMGC_CDK_CDK9_CDK9_ST	P50750	CDK9	P50750	CDK9	S353	N355S	355	Missense	proximal	2	no	2.921	2.816	EPSD;PhosphoSitePlus	ICGC	1.932	Down-regulation
CMGC_CDK_CDK9_CDK9_ST	P50750	CDK9	P50750	CDK9	S353	Q351H	351	Missense	proximal	-2	no	2.921	2.643	EPSD;PhosphoSitePlus	ICGC;COSMIC	1.932	Down-regulation
CMGC_CDK_CDK9_CDK9_ST	P50750	CDK9	P50750	CDK9	S353	Q348H	348	Missense	distal	-5	no	2.921	2.729	EPSD;PhosphoSitePlus	ICGC	1.932	Down-regulation
CMGC_CDK_CDK9_CDK9_ST	P50750	CDK9	P50750	CDK9	T354	N355S	355	Missense	proximal	1	no	3.986	3.306	EPSD;PhosphoSitePlus	ICGC	1.932	Down-regulation
CMGC_CDK_CDK9_CDK9_ST	P50750	CDK9	P50750	CDK9	T354	Q351H	351	Missense	distal	-3	no	3.986	4.014	EPSD;PhosphoSitePlus	ICGC;COSMIC	1.932	Up-regulation
CMGC_CDK_CDK9_CDK9_ST	P50750	CDK9	P50750	CDK9	T354	Q348H	348	Missense	distal	-6	no	3.986	3.776	EPSD;PhosphoSitePlus	ICGC	1.932	Down-regulation
CMGC_CDK_CDK9_CDK9_ST	P50750	CDK9	P50750	CDK9	S357	N355S	355	Missense	proximal	-2	no	2.355	2.481	EPSD	ICGC	1.932	Up-regulation
CMGC_CDK_CDK9_CDK9_ST	P50750	CDK9	P50750	CDK9	S357	Q351H	351	Missense	distal	-6	no	2.355	2.144	EPSD	ICGC;COSMIC	1.932	Down-regulation
CMGC_CDK_CDK9_CDK9_ST	P50750	CDK9	P50750	CDK9	T362	N355S	355	Missense	distal	-7	no	2.325	2.299	EPSD;PhosphoSitePlus	ICGC	1.932	Down-regulation
CMGC_CDK_CDK9_CDK9_ST	P84022	SMAD3	P50750	CDK9	T8	L15V	15	Missense	distal	7	no	5.649	5.631	EPSD	ICGC;COSMIC	1.932	Down-regulation
CMGC_CDK_CDK9_CDK9_ST	P84022	SMAD3	P50750	CDK9	S204	D201N	201	Missense	distal	-3	no	5.359	5.317	EPSD	ICGC	1.932	Down-regulation
CMGC_CDK_CDK9_CDK9_ST	P84022	SMAD3	P50750	CDK9	S208	D201N	201	Missense	distal	-7	no	6.205	6.175	PhosphoSitePlus;EPSD	ICGC	1.932	Down-regulation
CMGC_CDK_CDK9_CDK9_ST	P84022	SMAD3	P50750	CDK9	S213	L219F	219	Missense	distal	6	no	5.861	5.842	EPSD;PhosphoSitePlus	ICGC;COSMIC	1.932	Down-regulation
CMGC_CDK_CDK9_CDK9_ST	P84022	SMAD3	P50750	CDK9	S275	L273P	273	Missense	proximal	-2	no	1.690	2.479	EPSD	ICGC;COSMIC	1.932	Gain
CMGC_CDK_CDK9_CDK9_ST	P84022	SMAD3	P50750	CDK9	T412	G415V	415	Missense	distal	3	no	2.233	2.232	EPSD	ICGC	1.932	Down-regulation
CMGC_CDK_CDK9_CDK9_ST	P84022	SMAD3	P50750	CDK9	T412	L411F	411	Missense	proximal	-1	no	2.233	2.228	EPSD	ICGC;COSMIC	1.932	Down-regulation
CMGC_CDK_CDK9_CDK9_ST	P84022	SMAD3	P50750	CDK9	T412	L411I	411	Missense	proximal	-1	no	2.233	2.238	EPSD	ICGC;COSMIC	1.932	Up-regulation
CMGC_CDK_CDK9_CDK9_ST	P84022	SMAD3	P50750	CDK9	S416	S423T	423	Missense	distal	7	no	5.181	5.375	EPSD	ICGC;COSMIC	1.932	Up-regulation
CMGC_CDK_CDK9_CDK9_ST	P84022	SMAD3	P50750	CDK9	S416	S422F	422	Missense	distal	6	no	5.181	4.526	EPSD	ICGC;COSMIC	1.932	Down-regulation
CMGC_CDK_CDK9_CDK9_ST	P84022	SMAD3	P50750	CDK9	S416	G415V	415	Missense	proximal	-1	no	5.181	5.173	EPSD	ICGC	1.932	Down-regulation
CMGC_CDK_CDK9_CDK9_ST	P84022	SMAD3	P50750	CDK9	S416	S423N	423	Missense	distal	7	no	5.181	5.322	EPSD	ICGC;COSMIC	1.932	Up-regulation
CMGC_CDK_CDK9_CDK9_ST	P84022	SMAD3	P50750	CDK9	S416	L411F	411	Missense	distal	-5	no	5.181	5.168	EPSD	ICGC;COSMIC	1.932	Down-regulation
CMGC_CDK_CDK9_CDK9_ST	P84022	SMAD3	P50750	CDK9	S416	R420S	420	Missense	distal	4	no	5.181	5.295	EPSD	ICGC;COSMIC	1.932	Up-regulation
CMGC_CDK_CDK9_CDK9_ST	P84022	SMAD3	P50750	CDK9	S416	L411I	411	Missense	distal	-5	no	5.181	5.224	EPSD	ICGC;COSMIC	1.932	Up-regulation
CMGC_CDK_CDK9_CDK9_ST	P84022	SMAD3	P50750	CDK9	S422	S423T	423	Missense	proximal	1	no	2.348	2.063	EPSD	ICGC;COSMIC	1.932	Down-regulation
CMGC_CDK_CDK9_CDK9_ST	P84022	SMAD3	P50750	CDK9	S422	S422F	422	Missense	central	0	yes	2.348	0.000	EPSD	ICGC;COSMIC	1.932	Loss
CMGC_CDK_CDK9_CDK9_ST	P84022	SMAD3	P50750	CDK9	S422	S423N	423	Missense	proximal	1	no	2.348	3.028	EPSD	ICGC;COSMIC	1.932	Up-regulation
CMGC_CDK_CDK9_CDK9_ST	P84022	SMAD3	P50750	CDK9	S422	R420S	420	Missense	proximal	-2	no	2.348	2.665	EPSD	ICGC;COSMIC	1.932	Up-regulation
CMGC_CDK_CDK9_CDK9_ST	P24928	POLR2A	P50750	CDK9	S217	E223A	223	Missense	distal	6	no	5.452	5.360	EPSD	ICGC	1.932	Down-regulation
CMGC_CDK_CDK9_CDK9_ST	P24928	POLR2A	P50750	CDK9	T368	S362L	362	Missense	distal	-6	no	6.146	5.689	EPSD	ICGC	1.932	Down-regulation
CMGC_CDK_CDK9_CDK9_ST	P24928	POLR2A	P50750	CDK9	S530	M535T	535	Missense	distal	5	no	2.911	2.977	EPSD	ICGC;COSMIC	1.932	Up-regulation
CMGC_CDK_CDK9_CDK9_ST	P24928	POLR2A	P50750	CDK9	S777	V784F	784	Missense	distal	7	no	2.471	2.516	EPSD	ICGC	1.932	Up-regulation
CMGC_CDK_CDK9_CDK9_ST	P24928	POLR2A	P50750	CDK9	S777	G776A	776	Missense	proximal	-1	no	2.471	2.462	EPSD	ICGC	1.932	Down-regulation
CMGC_CDK_CDK9_CDK9_ST	P24928	POLR2A	P50750	CDK9	S1030	A1033S	1033	Missense	distal	3	no	1.749	2.016	EPSD	ICGC	1.932	Gain
CMGC_CDK_CDK9_CDK9_ST	P24928	POLR2A	P50750	CDK9	T1525	G1529D	1529	Missense	distal	4	no	5.379	5.332	PhosphoSitePlus	ICGC	1.932	Down-regulation
CMGC_CDK_CDK9_CDK9_ST	P24928	POLR2A	P50750	CDK9	S1532	G1529D	1529	Missense	distal	-3	no	5.269	5.270	EPSD	ICGC	1.932	Up-regulation
CMGC_CDK_CDK9_CDK9_ST	P24928	POLR2A	P50750	CDK9	T1568	W1565C	1565	Missense	distal	-3	no	5.440	5.441	EPSD	ICGC	1.932	Up-regulation
CMGC_CDK_CDK9_CDK9_ST	P24928	POLR2A	P50750	CDK9	T1568	G1570D	1570	Missense	proximal	2	no	5.440	5.450	EPSD	ICGC	1.932	Up-regulation
CMGC_CDK_CDK9_CDK9_ST	P24928	POLR2A	P50750	CDK9	S1571	W1565C	1565	Missense	distal	-6	no	5.570	5.557	EPSD	ICGC	1.932	Down-regulation
CMGC_CDK_CDK9_CDK9_ST	P24928	POLR2A	P50750	CDK9	S1571	G1570D	1570	Missense	proximal	-1	no	5.570	5.557	EPSD	ICGC	1.932	Down-regulation
CMGC_CDK_CDK9_CDK9_ST	P24928	POLR2A	P50750	CDK9	S1574	G1570D	1570	Missense	distal	-4	no	6.846	6.814	EPSD	ICGC	1.932	Down-regulation
CMGC_CDK_CDK9_CDK9_ST	P24928	POLR2A	P50750	CDK9	T1618	T1625P	1625	Missense	distal	7	no	2.563	2.406	EPSD;PhosphoSitePlus	ICGC	1.932	Down-regulation
CMGC_CDK_CDK9_CDK9_ST	P24928	POLR2A	P50750	CDK9	S1619	T1625P	1625	Missense	distal	6	no	4.556	4.888	EPSD;PhosphoSitePlus	ICGC	1.932	Up-regulation
CMGC_CDK_CDK9_CDK9_ST	P24928	POLR2A	P50750	CDK9	S1626	T1625P	1625	Missense	proximal	-1	no	4.234	4.246	EPSD	ICGC	1.932	Up-regulation
CMGC_CDK_CDK9_CDK9_ST	P24928	POLR2A	P50750	CDK9	S1647	S1644L	1644	Missense	distal	-3	no	4.281	4.371	EPSD	ICGC	1.932	Up-regulation
CMGC_CDK_CDK9_CDK9_ST	P24928	POLR2A	P50750	CDK9	S1661	S1665P	1665	Missense	distal	4	no	4.306	4.212	EPSD	ICGC	1.932	Down-regulation
CMGC_CDK_CDK9_CDK9_ST	P24928	POLR2A	P50750	CDK9	S1668	S1665P	1665	Missense	distal	-3	no	4.267	4.271	EPSD	ICGC	1.932	Up-regulation
CMGC_CDK_CDK9_CDK9_ST	P24928	POLR2A	P50750	CDK9	S1828	A1835T	1835	Missense	distal	7	no	2.157	2.052	EPSD	ICGC	1.932	Down-regulation
CMGC_CDK_CDK9_CDK9_ST	P24928	POLR2A	P50750	CDK9	S1829	A1835T	1835	Missense	distal	6	no	4.669	4.855	EPSD	ICGC	1.932	Up-regulation
CMGC_CDK_CDK9_CDK9_ST	P24928	POLR2A	P50750	CDK9	S1833	A1835T	1835	Missense	proximal	2	no	5.181	5.106	EPSD	ICGC	1.932	Down-regulation
CMGC_CDK_CDK9_CDK9_ST	P24928	POLR2A	P50750	CDK9	S1836	A1835T	1835	Missense	proximal	-1	no	4.664	4.687	EPSD	ICGC	1.932	Up-regulation
CMGC_CDK_CDK9_CDK9_ST	P24928	POLR2A	P50750	CDK9	T1840	A1835T	1835	Missense	distal	-5	no	4.259	4.391	EPSD	ICGC	1.932	Up-regulation
CMGC_CDK_CDK9_CDK9_ST	P24928	POLR2A	P50750	CDK9	S1843	S1850C	1850	Missense	distal	7	no	4.591	4.925	EPSD	ICGC	1.932	Up-regulation
CMGC_CDK_CDK9_CDK9_ST	P24928	POLR2A	P50750	CDK9	S1847	S1850C	1850	Missense	distal	3	no	4.003	3.699	EPSD	ICGC	1.932	Down-regulation
CMGC_CDK_CDK9_CDK9_ST	P24928	POLR2A	P50750	CDK9	S1847	T1854P	1854	Missense	distal	7	no	4.003	3.847	EPSD	ICGC	1.932	Down-regulation
CMGC_CDK_CDK9_CDK9_ST	P24928	POLR2A	P50750	CDK9	S1849	S1850C	1850	Missense	proximal	1	no	2.265	0.956	EPSD	ICGC	1.932	Loss
CMGC_CDK_CDK9_CDK9_ST	P24928	POLR2A	P50750	CDK9	S1849	T1854P	1854	Missense	distal	5	no	2.265	2.424	EPSD	ICGC	1.932	Up-regulation
CMGC_CDK_CDK9_CDK9_ST	P24928	POLR2A	P50750	CDK9	S1850	S1850C	1850	Missense	central	0	yes	4.655	0.000	EPSD	ICGC	1.932	Loss
CMGC_CDK_CDK9_CDK9_ST	P24928	POLR2A	P50750	CDK9	S1850	T1854P	1854	Missense	distal	4	no	4.655	4.653	EPSD	ICGC	1.932	Down-regulation
CMGC_CDK_CDK9_CDK9_ST	P24928	POLR2A	P50750	CDK9	T1854	S1861L	1861	Missense	distal	7	no	4.083	4.384	EPSD	ICGC	1.932	Up-regulation
CMGC_CDK_CDK9_CDK9_ST	P24928	POLR2A	P50750	CDK9	T1854	S1850C	1850	Missense	distal	-4	no	4.083	3.917	EPSD	ICGC	1.932	Down-regulation
CMGC_CDK_CDK9_CDK9_ST	P24928	POLR2A	P50750	CDK9	T1854	T1854P	1854	Missense	central	0	yes	4.083	0.000	EPSD	ICGC	1.932	Loss
CMGC_CDK_CDK9_CDK9_ST	P24928	POLR2A	P50750	CDK9	T1856	S1861L	1861	Missense	distal	5	no	2.320	1.875	EPSD	ICGC	1.932	Loss
CMGC_CDK_CDK9_CDK9_ST	P24928	POLR2A	P50750	CDK9	T1856	S1850C	1850	Missense	distal	-6	no	2.320	1.877	EPSD	ICGC	1.932	Loss
CMGC_CDK_CDK9_CDK9_ST	P24928	POLR2A	P50750	CDK9	T1856	T1854P	1854	Missense	proximal	-2	no	2.320	2.812	EPSD	ICGC	1.932	Up-regulation
CMGC_CDK_CDK9_CDK9_ST	P24928	POLR2A	P50750	CDK9	S1857	S1861L	1861	Missense	distal	4	no	4.315	4.180	EPSD	ICGC	1.932	Down-regulation
CMGC_CDK_CDK9_CDK9_ST	P24928	POLR2A	P50750	CDK9	S1857	S1850C	1850	Missense	distal	-7	no	4.315	4.379	EPSD	ICGC	1.932	Up-regulation
CMGC_CDK_CDK9_CDK9_ST	P24928	POLR2A	P50750	CDK9	S1857	T1854P	1854	Missense	distal	-3	no	4.315	4.265	EPSD	ICGC	1.932	Down-regulation
CMGC_CDK_CDK9_CDK9_ST	P24928	POLR2A	P50750	CDK9	S1861	S1861L	1861	Missense	central	0	yes	3.999	0.000	EPSD	ICGC	1.932	Loss
CMGC_CDK_CDK9_CDK9_ST	P24928	POLR2A	P50750	CDK9	S1861	T1854P	1854	Missense	distal	-7	no	3.999	3.960	EPSD	ICGC	1.932	Down-regulation
CMGC_CDK_CDK9_CDK9_ST	P24928	POLR2A	P50750	CDK9	T1863	S1861L	1861	Missense	proximal	-2	no	2.535	1.985	EPSD	ICGC	1.932	Down-regulation
CMGC_CDK_CDK9_CDK9_ST	P24928	POLR2A	P50750	CDK9	S1864	S1861L	1861	Missense	distal	-3	no	4.218	4.308	EPSD	ICGC	1.932	Up-regulation
CMGC_CDK_CDK9_CDK9_ST	P24928	POLR2A	P50750	CDK9	S1868	S1861L	1861	Missense	distal	-7	no	3.736	3.798	EPSD	ICGC	1.932	Up-regulation
CMGC_CDK_CDK9_CDK9_ST	P24928	POLR2A	P50750	CDK9	T1884	P1890S	1890	Missense	distal	6	no	2.285	2.316	EPSD	ICGC	1.932	Up-regulation
CMGC_CDK_CDK9_CDK9_ST	P24928	POLR2A	P50750	CDK9	T1885	P1890S	1890	Missense	distal	5	no	4.655	4.775	EPSD	ICGC	1.932	Up-regulation
CMGC_CDK_CDK9_CDK9_ST	P24928	POLR2A	P50750	CDK9	S1889	P1890S	1890	Missense	proximal	1	no	3.452	-0.282	EPSD	ICGC	1.932	Loss
CMGC_CDK_CDK9_CDK9_ST	P24928	POLR2A	P50750	CDK9	S1892	P1890S	1890	Missense	proximal	-2	no	4.537	4.299	EPSD	ICGC	1.932	Down-regulation
CMGC_CDK_CDK9_CDK9_ST	P24928	POLR2A	P50750	CDK9	S1896	P1890S	1890	Missense	distal	-6	no	3.763	3.631	EPSD	ICGC	1.932	Down-regulation
CMGC_CDK_CDK9_CDK9_ST	P24928	POLR2A	P50750	CDK9	S1913	S1920F	1920	Missense	distal	7	no	4.458	4.786	EPSD	ICGC	1.932	Up-regulation
CMGC_CDK_CDK9_CDK9_ST	P24928	POLR2A	P50750	CDK9	T1915	S1920F	1920	Missense	distal	5	no	2.055	1.578	EPSD	ICGC	1.932	Loss
CMGC_CDK_CDK9_CDK9_ST	P24928	POLR2A	P50750	CDK9	T1915	P1921H	1921	Missense	distal	6	no	2.055	1.578	EPSD	ICGC	1.932	Loss
CMGC_CDK_CDK9_CDK9_ST	P24928	POLR2A	P50750	CDK9	S1917	S1920F	1920	Missense	distal	3	no	4.197	3.894	EPSD	ICGC	1.932	Down-regulation
CMGC_CDK_CDK9_CDK9_ST	P24928	POLR2A	P50750	CDK9	S1917	P1921H	1921	Missense	distal	4	no	4.197	4.166	EPSD	ICGC	1.932	Down-regulation
CMGC_CDK_CDK9_CDK9_ST	P24928	POLR2A	P50750	CDK9	T1919	S1920F	1920	Missense	proximal	1	no	2.788	1.486	EPSD	ICGC	1.932	Loss
CMGC_CDK_CDK9_CDK9_ST	P24928	POLR2A	P50750	CDK9	T1919	P1921H	1921	Missense	proximal	2	no	2.788	2.906	EPSD	ICGC	1.932	Up-regulation
CMGC_CDK_CDK9_CDK9_ST	P24928	POLR2A	P50750	CDK9	S1920	S1927I	1927	Missense	distal	7	no	4.157	4.445	EPSD	ICGC	1.932	Up-regulation
CMGC_CDK_CDK9_CDK9_ST	P24928	POLR2A	P50750	CDK9	S1920	S1920F	1920	Missense	central	0	yes	4.157	0.000	EPSD	ICGC	1.932	Loss
CMGC_CDK_CDK9_CDK9_ST	P24928	POLR2A	P50750	CDK9	S1920	P1921H	1921	Missense	proximal	1	no	4.157	-0.418	EPSD	ICGC	1.932	Loss
CMGC_CDK_CDK9_CDK9_ST	P24928	POLR2A	P50750	CDK9	S1924	S1927I	1927	Missense	distal	3	no	3.881	3.614	EPSD	ICGC	1.932	Down-regulation
CMGC_CDK_CDK9_CDK9_ST	P24928	POLR2A	P50750	CDK9	S1924	S1920F	1920	Missense	distal	-4	no	3.881	3.716	EPSD	ICGC	1.932	Down-regulation
CMGC_CDK_CDK9_CDK9_ST	P24928	POLR2A	P50750	CDK9	S1924	P1921H	1921	Missense	distal	-3	no	3.881	3.946	EPSD	ICGC	1.932	Up-regulation
CMGC_CDK_CDK9_CDK9_ST	P24928	POLR2A	P50750	CDK9	T1926	S1927I	1927	Missense	proximal	1	no	2.763	1.349	EPSD	ICGC	1.932	Loss
CMGC_CDK_CDK9_CDK9_ST	P24928	POLR2A	P50750	CDK9	T1926	S1920F	1920	Missense	distal	-6	no	2.763	2.325	EPSD	ICGC	1.932	Down-regulation
CMGC_CDK_CDK9_CDK9_ST	P24928	POLR2A	P50750	CDK9	T1926	P1921H	1921	Missense	distal	-5	no	2.763	2.488	EPSD	ICGC	1.932	Down-regulation
CMGC_CDK_CDK9_CDK9_ST	P24928	POLR2A	P50750	CDK9	S1927	S1927I	1927	Missense	central	0	yes	4.481	0.000	EPSD	ICGC	1.932	Loss
CMGC_CDK_CDK9_CDK9_ST	P24928	POLR2A	P50750	CDK9	S1927	S1920F	1920	Missense	distal	-7	no	4.481	4.543	EPSD	ICGC	1.932	Up-regulation
CMGC_CDK_CDK9_CDK9_ST	P24928	POLR2A	P50750	CDK9	S1927	P1921H	1921	Missense	distal	-6	no	4.481	4.018	EPSD	ICGC	1.932	Down-regulation
CMGC_CDK_CDK9_CDK9_ST	P24928	POLR2A	P50750	CDK9	T1929	S1927I	1927	Missense	proximal	-2	no	2.071	1.588	EPSD	ICGC	1.932	Loss
CMGC_CDK_CDK9_CDK9_ST	P24928	POLR2A	P50750	CDK9	S1931	S1927I	1927	Missense	distal	-4	no	4.637	4.494	EPSD	ICGC	1.932	Down-regulation
CMGC_CDK_CDK9_CDK9_ST	P24928	POLR2A	P50750	CDK9	S1931	S1938P	1938	Missense	distal	7	no	4.637	4.675	EPSD	ICGC	1.932	Up-regulation
CMGC_CDK_CDK9_CDK9_ST	P24928	POLR2A	P50750	CDK9	S1934	S1927I	1927	Missense	distal	-7	no	4.273	4.330	EPSD	ICGC	1.932	Up-regulation
CMGC_CDK_CDK9_CDK9_ST	P24928	POLR2A	P50750	CDK9	S1934	S1938P	1938	Missense	distal	4	no	4.273	4.180	EPSD	ICGC	1.932	Down-regulation
CMGC_CDK_CDK9_CDK9_ST	P24928	POLR2A	P50750	CDK9	S1941	S1938P	1938	Missense	distal	-3	no	4.343	4.348	EPSD	ICGC	1.932	Up-regulation
CMGC_CDK_CDK9_CDK9_ST	P24928	POLR2A	P50750	CDK9	T1943	S1938P	1938	Missense	distal	-5	no	3.014	2.929	EPSD	ICGC	1.932	Down-regulation
CMGC_CDK_CDK9_CDK9_ST	P24928	POLR2A	P50750	CDK9	S1944	S1938P	1938	Missense	distal	-6	no	5.921	6.052	EPSD	ICGC	1.932	Up-regulation
CMGC_CDK_CDK9_CDK9_ST	P24928	POLR2A	P50750	CDK9	S1948	P1952H	1952	Missense	distal	4	no	5.389	5.359	EPSD	ICGC	1.932	Down-regulation
CMGC_CDK_CDK9_CDK9_ST	P24928	POLR2A	P50750	CDK9	T1950	P1952H	1952	Missense	proximal	2	no	3.732	3.850	EPSD	ICGC	1.932	Up-regulation
CMGC_CDK_CDK9_CDK9_ST	P24928	POLR2A	P50750	CDK9	S1951	P1952H	1952	Missense	proximal	1	no	6.457	1.882	EPSD	ICGC	1.932	Loss
CMGC_CDK_CDK9_CDK9_ST	P24928	POLR2A	P50750	CDK9	T1953	P1952H	1952	Missense	proximal	-1	no	3.266	3.243	EPSD	ICGC	1.932	Down-regulation
CMGC_CDK_CDK9_CDK9_ST	P24928	POLR2A	P50750	CDK9	T1957	P1963L	1963	Missense	distal	6	no	3.835	3.229	EPSD	ICGC	1.932	Down-regulation
CMGC_CDK_CDK9_CDK9_ST	P24928	POLR2A	P50750	CDK9	T1957	P1952H	1952	Missense	distal	-5	no	3.835	3.560	EPSD	ICGC	1.932	Down-regulation
CMGC_CDK_CDK9_CDK9_ST	P24928	POLR2A	P50750	CDK9	S1958	P1963L	1963	Missense	distal	5	no	6.241	5.916	EPSD	ICGC	1.932	Down-regulation
CMGC_CDK_CDK9_CDK9_ST	P24928	POLR2A	P50750	CDK9	S1958	P1952H	1952	Missense	distal	-6	no	6.241	5.779	EPSD	ICGC	1.932	Down-regulation
CMGC_CDK_CDK9_CDK9_ST	P24928	POLR2A	P50750	CDK9	S1962	P1963L	1963	Missense	proximal	1	no	4.945	-0.653	EPSD	ICGC	1.932	Loss
CMGC_CDK_CDK9_CDK9_ST	Q6PGQ7	BORA	P50750	CDK9	T52	P53A	53	Missense	proximal	1	no	4.733	-0.432	EPSD	ICGC	1.932	Loss
CMGC_CDK_CDK9_CDK9_ST	Q6PGQ7	BORA	P50750	CDK9	T52	G54E	54	Missense	proximal	2	no	4.733	4.692	EPSD	ICGC	1.932	Down-regulation
CMGC_CDK_CDK9_CDK9_ST	Q6PGQ7	BORA	P50750	CDK9	S112	T105I	105	Missense	distal	-7	no	3.786	3.809	EPSD	ICGC	1.932	Up-regulation
CMGC_CDK_CDK9_CDK9_ST	Q6PGQ7	BORA	P50750	CDK9	S112	V108F	108	Missense	distal	-4	no	3.786	3.767	EPSD	ICGC	1.932	Down-regulation
CMGC_CDK_CDK9_CDK9_ST	Q6PGQ7	BORA	P50750	CDK9	S112	D116V	116	Missense	distal	4	no	3.786	3.791	EPSD	ICGC	1.932	Up-regulation
CMGC_CDK_CDK9_CDK9_ST	Q6PGQ7	BORA	P50750	CDK9	S112	D116Y	116	Missense	distal	4	no	3.786	3.796	EPSD	ICGC	1.932	Up-regulation
CMGC_CDK_CDK9_CDK9_ST	Q6PGQ7	BORA	P50750	CDK9	T131	N132Y	132	Missense	proximal	1	no	1.966	0.507	EPSD	ICGC	1.932	Loss
CMGC_CDK_CDK9_CDK9_ST	Q6PGQ7	BORA	P50750	CDK9	S137	T131S	131	Missense	distal	-6	no	5.032	5.266	EPSD	ICGC	1.932	Up-regulation
CMGC_CDK_CDK9_CDK9_ST	Q6PGQ7	BORA	P50750	CDK9	S137	N132Y	132	Missense	distal	-5	no	5.032	4.861	EPSD	ICGC	1.932	Down-regulation
CMGC_CDK_CDK9_CDK9_ST	Q6PGQ7	BORA	P50750	CDK9	S183	S189Y	189	Missense	distal	6	no	4.367	3.817	EPSD	ICGC	1.932	Down-regulation
CMGC_CDK_CDK9_CDK9_ST	Q6PGQ7	BORA	P50750	CDK9	S183	E178G	178	Missense	distal	-5	no	4.367	4.353	EPSD	ICGC	1.932	Down-regulation
CMGC_CDK_CDK9_CDK9_ST	Q6PGQ7	BORA	P50750	CDK9	S233	L232F	232	Missense	proximal	-1	no	4.635	4.630	EPSD	ICGC	1.932	Down-regulation
CMGC_CDK_CDK9_CDK9_ST	Q6PGQ7	BORA	P50750	CDK9	S239	L232F	232	Missense	distal	-7	no	5.729	5.730	EPSD	ICGC	1.932	Up-regulation
CMGC_CDK_CDK9_CDK9_ST	Q6PGQ7	BORA	P50750	CDK9	T243	S250Y	250	Missense	distal	7	no	3.924	4.213	EPSD	ICGC	1.932	Up-regulation
CMGC_CDK_CDK9_CDK9_ST	Q6PGQ7	BORA	P50750	CDK9	T243	G247V	247	Missense	distal	4	no	3.924	3.882	EPSD	ICGC	1.932	Down-regulation
CMGC_CDK_CDK9_CDK9_ST	Q6PGQ7	BORA	P50750	CDK9	S252	S250Y	250	Missense	proximal	-2	no	5.464	5.053	EPSD	ICGC	1.932	Down-regulation
CMGC_CDK_CDK9_CDK9_ST	Q6PGQ7	BORA	P50750	CDK9	S252	G247V	247	Missense	distal	-5	no	5.464	5.402	EPSD	ICGC	1.932	Down-regulation
CMGC_CDK_CDK9_CDK9_ST	Q6PGQ7	BORA	P50750	CDK9	S252	S252N	252	Missense	central	0	yes	5.464	0.000	EPSD	ICGC	1.932	Loss
CMGC_CDK_CDK9_CDK9_ST	Q6PGQ7	BORA	P50750	CDK9	S268	S262R	262	Missense	distal	-6	no	5.318	5.031	EPSD	ICGC	1.932	Down-regulation
CMGC_CDK_CDK9_CDK9_ST	Q6PGQ7	BORA	P50750	CDK9	S325	P326Q	326	Missense	proximal	1	no	5.008	1.453	PhosphoSitePlus	ICGC	1.932	Loss
CMGC_CDK_CDK9_CDK9_ST	Q6PGQ7	BORA	P50750	CDK9	S325	P332T	332	Missense	distal	7	no	5.008	5.165	PhosphoSitePlus	ICGC	1.932	Up-regulation
CMGC_CDK_CDK9_CDK9_ST	Q6PGQ7	BORA	P50750	CDK9	S331	P326Q	326	Missense	distal	-5	no	5.706	5.623	EPSD	ICGC	1.932	Down-regulation
CMGC_CDK_CDK9_CDK9_ST	Q6PGQ7	BORA	P50750	CDK9	S331	P332T	332	Missense	proximal	1	no	5.706	1.687	EPSD	ICGC	1.932	Loss
CMGC_CDK_CDK9_CDK9_ST	Q9H0D6	XRN2	P50750	CDK9	T670	T670P	670	Missense	central	0	yes	4.198	0.000	EPSD	ICGC	1.932	Loss
CMGC_CDK_CDK9_CDK9_ST	Q9H0D6	XRN2	P50750	CDK9	S790	P797S	797	Missense	distal	7	no	2.214	2.176	EPSD	ICGC	1.932	Down-regulation
CMGC_CDK_CDK9_CDK9_ST	P10275	AR	P50750	CDK9	S96	E93K	93	Missense	distal	-3	no	4.065	4.059	EPSD	ICGC	1.932	Down-regulation
CMGC_CDK_CDK9_CDK9_ST	P10275	AR	P50750	CDK9	S258	G260V	260	Missense	proximal	2	no	4.086	4.076	EPSD	ICGC;COSMIC	1.932	Down-regulation
CMGC_CDK_CDK9_CDK9_ST	P10275	AR	P50750	CDK9	T282	A288T	288	Missense	distal	6	no	4.856	5.041	EPSD	ICGC;COSMIC	1.932	Up-regulation
CMGC_CDK_CDK9_CDK9_ST	P10275	AR	P50750	CDK9	T282	R280L	280	Missense	proximal	-2	no	4.856	4.623	EPSD	ICGC	1.932	Down-regulation
CMGC_CDK_CDK9_CDK9_ST	P10275	AR	P50750	CDK9	T282	A288D	288	Missense	distal	6	no	4.856	4.803	EPSD	ICGC;COSMIC	1.932	Down-regulation
CMGC_CDK_CDK9_CDK9_ST	P10275	AR	P50750	CDK9	S310	T317A	317	Missense	distal	7	no	4.651	4.756	EPSD	ICGC;COSMIC	1.932	Up-regulation
CMGC_CDK_CDK9_CDK9_ST	P10275	AR	P50750	CDK9	S310	T303S	303	Missense	distal	-7	no	4.651	4.616	EPSD	ICGC;COSMIC	1.932	Down-regulation
CMGC_CDK_CDK9_CDK9_ST	P10275	AR	P50750	CDK9	S310	G314R	314	Missense	distal	4	no	4.651	4.635	EPSD	ICGC	1.932	Down-regulation
CMGC_CDK_CDK9_CDK9_ST	P10275	AR	P50750	CDK9	S516	Y514H	514	Missense	proximal	-2	no	5.379	5.402	EPSD	ICGC;GDSC;CCLE	1.932	Up-regulation
CMGC_CDK_CDK9_CDK9_ST	P10275	AR	P50750	CDK9	S516	S516I	516	Missense	central	0	yes	5.379	0.000	EPSD	ICGC	1.932	Loss
CMGC_CDK_CDK9_CDK9_ST	P10275	AR	P50750	CDK9	S516	V509L	509	Missense	distal	-7	no	5.379	5.389	EPSD	ICGC;COSMIC	1.932	Up-regulation
CMGC_CDK_CDK9_CDK9_ST	Q15596	NCOA2	P50750	CDK9	S29	P30T	30	Missense	proximal	1	no	6.112	2.093	EPSD	ICGC	1.932	Down-regulation
CMGC_CDK_CDK9_CDK9_ST	Q15596	NCOA2	P50750	CDK9	S195	H196N	196	Missense	proximal	1	no	0.594	2.114	EPSD	ICGC	1.932	Gain
CMGC_CDK_CDK9_CDK9_ST	Q15596	NCOA2	P50750	CDK9	S400	P403T	403	Missense	distal	3	no	2.325	2.110	EPSD	ICGC	1.932	Down-regulation
CMGC_CDK_CDK9_CDK9_ST	Q15596	NCOA2	P50750	CDK9	S400	L395M	395	Missense	distal	-5	no	2.325	2.434	EPSD	ICGC	1.932	Up-regulation
CMGC_CDK_CDK9_CDK9_ST	Q15596	NCOA2	P50750	CDK9	S400	A407P	407	Missense	distal	7	no	2.325	2.063	EPSD	ICGC;COSMIC	1.932	Down-regulation
CMGC_CDK_CDK9_CDK9_ST	Q15596	NCOA2	P50750	CDK9	S400	P403H	403	Missense	distal	3	no	2.325	2.077	EPSD	ICGC;COSMIC	1.932	Down-regulation
CMGC_CDK_CDK9_CDK9_ST	Q15596	NCOA2	P50750	CDK9	S402	P403T	403	Missense	proximal	1	no	4.947	0.928	EPSD	ICGC	1.932	Loss
CMGC_CDK_CDK9_CDK9_ST	Q15596	NCOA2	P50750	CDK9	S402	L395M	395	Missense	distal	-7	no	4.947	4.933	EPSD	ICGC	1.932	Down-regulation
CMGC_CDK_CDK9_CDK9_ST	Q15596	NCOA2	P50750	CDK9	S402	A407P	407	Missense	distal	5	no	4.947	5.225	EPSD	ICGC;COSMIC	1.932	Up-regulation
CMGC_CDK_CDK9_CDK9_ST	Q15596	NCOA2	P50750	CDK9	S402	P403H	403	Missense	proximal	1	no	4.947	0.372	EPSD	ICGC;COSMIC	1.932	Loss
CMGC_CDK_CDK9_CDK9_ST	Q15596	NCOA2	P50750	CDK9	S421	D416E	416	Missense	distal	-5	no	2.627	2.723	EPSD	ICGC	1.932	Up-regulation
CMGC_CDK_CDK9_CDK9_ST	Q15596	NCOA2	P50750	CDK9	S421	L419I	419	Missense	proximal	-2	no	2.627	2.694	EPSD	ICGC;COSMIC	1.932	Up-regulation
CMGC_CDK_CDK9_CDK9_ST	Q15596	NCOA2	P50750	CDK9	T457	A455E	455	Missense	proximal	-2	no	5.049	5.180	EPSD	ICGC	1.932	Up-regulation
CMGC_CDK_CDK9_CDK9_ST	Q15596	NCOA2	P50750	CDK9	S469	L465I	465	Missense	distal	-4	no	5.622	5.634	EPSD;PhosphoSitePlus	ICGC	1.932	Up-regulation
CMGC_CDK_CDK9_CDK9_ST	Q15596	NCOA2	P50750	CDK9	S487	P488L	488	Missense	proximal	1	no	5.333	-0.265	EPSD;PhosphoSitePlus	ICGC;COSMIC	1.932	Loss
CMGC_CDK_CDK9_CDK9_ST	Q15596	NCOA2	P50750	CDK9	S487	H490N	490	Missense	distal	3	no	5.333	5.418	EPSD;PhosphoSitePlus	ICGC	1.932	Up-regulation
CMGC_CDK_CDK9_CDK9_ST	Q15596	NCOA2	P50750	CDK9	S493	S499N	499	Missense	distal	6	no	5.367	5.118	PhosphoSitePlus;EPSD	ICGC;COSMIC	1.932	Down-regulation
CMGC_CDK_CDK9_CDK9_ST	Q15596	NCOA2	P50750	CDK9	S493	P488L	488	Missense	distal	-5	no	5.367	4.988	PhosphoSitePlus;EPSD	ICGC;COSMIC	1.932	Down-regulation
CMGC_CDK_CDK9_CDK9_ST	Q15596	NCOA2	P50750	CDK9	S493	H490N	490	Missense	distal	-3	no	5.367	5.338	PhosphoSitePlus;EPSD	ICGC	1.932	Down-regulation
CMGC_CDK_CDK9_CDK9_ST	Q15596	NCOA2	P50750	CDK9	S499	S499N	499	Missense	central	0	yes	5.856	0.000	EPSD;PhosphoSitePlus	ICGC;COSMIC	1.932	Loss
CMGC_CDK_CDK9_CDK9_ST	Q15596	NCOA2	P50750	CDK9	S554	L552S	552	Missense	proximal	-2	no	3.599	4.150	EPSD	ICGC;COSMIC	1.932	Up-regulation
CMGC_CDK_CDK9_CDK9_ST	Q15596	NCOA2	P50750	CDK9	S554	S551L	551	Missense	distal	-3	no	3.599	3.689	EPSD	ICGC	1.932	Up-regulation
CMGC_CDK_CDK9_CDK9_ST	Q15596	NCOA2	P50750	CDK9	S699	A704T	704	Missense	distal	5	no	4.239	4.359	EPSD	ICGC;COSMIC	1.932	Up-regulation
CMGC_CDK_CDK9_CDK9_ST	Q15596	NCOA2	P50750	CDK9	S720	L715P	715	Missense	distal	-5	no	1.924	2.303	EPSD	ICGC;COSMIC	1.932	Gain
CMGC_CDK_CDK9_CDK9_ST	Q15596	NCOA2	P50750	CDK9	S721	G725V	725	Missense	distal	4	no	2.132	2.090	EPSD	ICGC;COSMIC	1.932	Down-regulation
CMGC_CDK_CDK9_CDK9_ST	Q15596	NCOA2	P50750	CDK9	S721	S716R	716	Missense	distal	-5	no	2.132	1.803	EPSD	ICGC	1.932	Loss
CMGC_CDK_CDK9_CDK9_ST	Q15596	NCOA2	P50750	CDK9	S721	L715P	715	Missense	distal	-6	no	2.132	2.722	EPSD	ICGC;COSMIC	1.932	Up-regulation
CMGC_CDK_CDK9_CDK9_ST	Q15596	NCOA2	P50750	CDK9	S736	A743T	743	Missense	distal	7	no	5.598	5.494	EPSD	ICGC;COSMIC	1.932	Down-regulation
CMGC_CDK_CDK9_CDK9_ST	Q15596	NCOA2	P50750	CDK9	S736	A743E	743	Missense	distal	7	no	5.598	5.530	EPSD	ICGC;COSMIC	1.932	Down-regulation
CMGC_CDK_CDK9_CDK9_ST	Q15596	NCOA2	P50750	CDK9	T763	D756Y	756	Missense	distal	-7	no	4.624	4.623	EPSD	ICGC;COSMIC	1.932	Down-regulation
CMGC_CDK_CDK9_CDK9_ST	Q15596	NCOA2	P50750	CDK9	S777	T779A	779	Missense	proximal	2	no	1.996	2.071	EPSD	ICGC;COSMIC	1.932	Up-regulation
CMGC_CDK_CDK9_CDK9_ST	Q15596	NCOA2	P50750	CDK9	T854	K860I	860	Missense	distal	6	no	6.136	5.942	EPSD	ICGC;COSMIC	1.932	Down-regulation
CMGC_CDK_CDK9_CDK9_ST	Q15596	NCOA2	P50750	CDK9	S868	T869N	869	Missense	proximal	1	no	1.282	2.248	EPSD	ICGC	1.932	Gain
CMGC_CDK_CDK9_CDK9_ST	Q15596	NCOA2	P50750	CDK9	S895	I891T	891	Missense	distal	-4	no	5.047	5.095	EPSD	ICGC;COSMIC	1.932	Up-regulation
CMGC_CDK_CDK9_CDK9_ST	Q15596	NCOA2	P50750	CDK9	S895	L889H	889	Missense	distal	-6	no	5.047	5.174	EPSD	ICGC;COSMIC	1.932	Up-regulation
CMGC_CDK_CDK9_CDK9_ST	Q15596	NCOA2	P50750	CDK9	S895	D890N	890	Missense	distal	-5	no	5.047	5.262	EPSD	ICGC;COSMIC	1.932	Up-regulation
CMGC_CDK_CDK9_CDK9_ST	Q15596	NCOA2	P50750	CDK9	S1059	P1066Q	1066	Missense	distal	7	no	5.295	5.390	EPSD	ICGC;COSMIC	1.932	Up-regulation
CMGC_CDK_CDK9_CDK9_ST	Q15596	NCOA2	P50750	CDK9	S1072	P1068A	1068	Missense	distal	-4	no	5.249	5.124	EPSD	ICGC	1.932	Down-regulation
CMGC_CDK_CDK9_CDK9_ST	Q15596	NCOA2	P50750	CDK9	S1072	S1072F	1072	Missense	central	0	yes	5.249	0.000	EPSD	ICGC;COSMIC	1.932	Loss
CMGC_CDK_CDK9_CDK9_ST	Q15596	NCOA2	P50750	CDK9	S1072	P1066Q	1066	Missense	distal	-6	no	5.249	4.997	EPSD	ICGC;COSMIC	1.932	Down-regulation
CMGC_CDK_CDK9_CDK9_ST	Q15596	NCOA2	P50750	CDK9	S1211	Q1204K	1204	Missense	distal	-7	no	2.248	2.261	EPSD	ICGC	1.932	Up-regulation
CMGC_CDK_CDK9_CDK9_ST	Q15596	NCOA2	P50750	CDK9	T1273	S1275N	1275	Missense	proximal	2	no	4.922	5.027	EPSD	ICGC;COSMIC	1.932	Up-regulation
CMGC_CDK_CDK9_CDK9_ST	Q15596	NCOA2	P50750	CDK9	T1273	A1278D	1278	Missense	distal	5	no	4.922	4.877	EPSD	ICGC	1.932	Down-regulation
CMGC_CDK_CDK9_CDK9_ST	Q15596	NCOA2	P50750	CDK9	T1273	L1270F	1270	Missense	distal	-3	no	4.922	4.923	EPSD	ICGC;COSMIC	1.932	Up-regulation
CMGC_CDK_CDK9_CDK9_ST	P06400	RB1	P50750	CDK9	T5	A10S	10	Missense	distal	5	no	4.174	4.572	EPSD	ICGC	1.932	Up-regulation
CMGC_CDK_CDK9_CDK9_ST	P06400	RB1	P50750	CDK9	T5	A11T	11	Missense	distal	6	no	4.174	4.359	EPSD	ICGC;COSMIC	1.932	Up-regulation
CMGC_CDK_CDK9_CDK9_ST	P06400	RB1	P50750	CDK9	S230	D224E	224	Missense	distal	-6	no	3.314	3.413	EPSD	ICGC;COSMIC	1.932	Up-regulation
CMGC_CDK_CDK9_CDK9_ST	P06400	RB1	P50750	CDK9	S249	R251L	251	Missense	proximal	2	no	5.182	5.242	EPSD	ICGC	1.932	Up-regulation
CMGC_CDK_CDK9_CDK9_ST	P06400	RB1	P50750	CDK9	S249	G256C	256	Missense	distal	7	no	5.182	5.246	EPSD	ICGC	1.932	Up-regulation
CMGC_CDK_CDK9_CDK9_ST	P06400	RB1	P50750	CDK9	T252	R251L	251	Missense	proximal	-1	no	5.473	5.453	EPSD	ICGC	1.932	Down-regulation
CMGC_CDK_CDK9_CDK9_ST	P06400	RB1	P50750	CDK9	T252	G256C	256	Missense	distal	4	no	5.473	5.416	EPSD	ICGC	1.932	Down-regulation
CMGC_CDK_CDK9_CDK9_ST	P06400	RB1	P50750	CDK9	T356	Q354H	354	Missense	proximal	-2	no	4.712	4.434	EPSD	ICGC;COSMIC	1.932	Down-regulation
CMGC_CDK_CDK9_CDK9_ST	P06400	RB1	P50750	CDK9	S567	L572I	572	Missense	distal	5	no	4.316	4.343	EPSD	ICGC;COSMIC	1.932	Up-regulation
CMGC_CDK_CDK9_CDK9_ST	P06400	RB1	P50750	CDK9	S567	D571Y	571	Missense	distal	4	no	4.316	4.325	EPSD	ICGC	1.932	Up-regulation
CMGC_CDK_CDK9_CDK9_ST	P06400	RB1	P50750	CDK9	S567	W563L	563	Missense	distal	-4	no	4.316	4.324	EPSD	ICGC	1.932	Up-regulation
CMGC_CDK_CDK9_CDK9_ST	P06400	RB1	P50750	CDK9	S567	A562P	562	Missense	distal	-5	no	4.316	4.648	EPSD	ICGC;COSMIC;GDSC;CCLE	1.932	Up-regulation
CMGC_CDK_CDK9_CDK9_ST	P06400	RB1	P50750	CDK9	S567	L564F	564	Missense	distal	-3	no	4.316	4.318	EPSD	ICGC	1.932	Up-regulation
CMGC_CDK_CDK9_CDK9_ST	P06400	RB1	P50750	CDK9	S780	P783L	783	Missense	distal	3	no	5.296	4.950	EPSD	ICGC	1.932	Down-regulation
CMGC_CDK_CDK9_CDK9_ST	P06400	RB1	P50750	CDK9	S788	P783L	783	Missense	distal	-5	no	5.074	4.695	EPSD	ICGC	1.932	Down-regulation
CMGC_CDK_CDK9_CDK9_ST	P06400	RB1	P50750	CDK9	S794	L797S	797	Missense	distal	3	no	2.098	2.409	EPSD	ICGC;COSMIC	1.932	Up-regulation
CMGC_CDK_CDK9_CDK9_ST	P06400	RB1	P50750	CDK9	S794	G801E	801	Missense	distal	7	no	2.098	2.058	EPSD	ICGC	1.932	Down-regulation
CMGC_CDK_CDK9_CDK9_ST	P06400	RB1	P50750	CDK9	S795	L797S	797	Missense	proximal	2	no	5.687	5.484	PhosphoSitePlus;EPSD	ICGC;COSMIC	1.932	Down-regulation
CMGC_CDK_CDK9_CDK9_ST	P06400	RB1	P50750	CDK9	S795	G801E	801	Missense	distal	6	no	5.687	5.739	PhosphoSitePlus;EPSD	ICGC	1.932	Up-regulation
CMGC_CDK_CDK9_CDK9_ST	P06400	RB1	P50750	CDK9	S807	G801E	801	Missense	distal	-6	no	4.492	4.567	EPSD;PhosphoSitePlus	ICGC	1.932	Up-regulation
CMGC_CDK_CDK9_CDK9_ST	P06400	RB1	P50750	CDK9	S866	K873E	873	Missense	distal	7	no	2.057	2.075	EPSD	ICGC;COSMIC	1.932	Up-regulation
CMGC_CDK_CDK9_CDK9_ST	P06400	RB1	P50750	CDK9	S866	P871Q	871	Missense	distal	5	no	2.057	2.018	EPSD	ICGC;COSMIC	1.932	Down-regulation
CMGC_CDK_CDK9_CDK9_ST	P06400	RB1	P50750	CDK9	T905	R910Q	910	Missense	distal	5	no	2.236	2.412	EPSD	ICGC	1.932	Up-regulation
CMGC_CDK_CDK9_CDK9_ST	P04637	TP53	P50750	CDK9	S15	E11K	11	Missense	distal	-4	no	1.964	1.979	EPSD	ICGC;COSMIC	1.932	Up-regulation
CMGC_CDK_CDK9_CDK9_ST	P04637	TP53	P50750	CDK9	S33	P34L	34	Missense	proximal	1	no	5.662	0.064	EPSD;PhosphoSitePlus	ICGC;COSMIC	1.932	Loss
CMGC_CDK_CDK9_CDK9_ST	P04637	TP53	P50750	CDK9	S33	S33F	33	Missense	central	0	yes	5.662	0.000	EPSD;PhosphoSitePlus	ICGC;COSMIC	1.932	Loss
CMGC_CDK_CDK9_CDK9_ST	P04637	TP53	P50750	CDK9	S33	N30I	30	Missense	distal	-3	no	5.662	5.703	EPSD;PhosphoSitePlus	ICGC	1.932	Up-regulation
CMGC_CDK_CDK9_CDK9_ST	P04637	TP53	P50750	CDK9	S46	D48G	48	Missense	proximal	2	no	4.557	4.547	EPSD	ICGC;COSMIC	1.932	Down-regulation
CMGC_CDK_CDK9_CDK9_ST	P04637	TP53	P50750	CDK9	S46	Q52K	52	Missense	distal	6	no	4.557	4.370	EPSD	ICGC	1.932	Down-regulation
CMGC_CDK_CDK9_CDK9_ST	P04637	TP53	P50750	CDK9	T81	A88D	88	Missense	distal	7	no	4.981	4.982	EPSD	ICGC	1.932	Up-regulation
CMGC_CDK_CDK9_CDK9_ST	P04637	TP53	P50750	CDK9	T81	P87Q	87	Missense	distal	6	no	4.981	4.798	EPSD	ICGC;COSMIC	1.932	Down-regulation
CMGC_CDK_CDK9_CDK9_ST	P04637	TP53	P50750	CDK9	S127	T125R	125	Missense	proximal	-2	no	4.849	4.785	EPSD	ICGC;COSMIC	1.932	Down-regulation
CMGC_CDK_CDK9_CDK9_ST	P04637	TP53	P50750	CDK9	S127	F134C	134	Missense	distal	7	no	4.849	4.855	EPSD	ICGC;COSMIC;CCLE	1.932	Up-regulation
CMGC_CDK_CDK9_CDK9_ST	P04637	TP53	P50750	CDK9	S127	C124G	124	Missense	distal	-3	no	4.849	4.839	EPSD	ICGC;COSMIC	1.932	Down-regulation
CMGC_CDK_CDK9_CDK9_ST	P04637	TP53	P50750	CDK9	S127	C124R	124	Missense	distal	-3	no	4.849	4.824	EPSD	ICGC;COSMIC;GDSC;CCLE	1.932	Down-regulation
CMGC_CDK_CDK9_CDK9_ST	P04637	TP53	P50750	CDK9	S127	L130H	130	Missense	distal	3	no	4.849	4.947	EPSD	ICGC;COSMIC	1.932	Up-regulation
CMGC_CDK_CDK9_CDK9_ST	P04637	TP53	P50750	CDK9	S127	T125A	125	Missense	proximal	-2	no	4.849	4.641	EPSD	ICGC;COSMIC	1.932	Down-regulation
CMGC_CDK_CDK9_CDK9_ST	P04637	TP53	P50750	CDK9	S127	K120N	120	Missense	distal	-7	no	4.849	4.838	EPSD	ICGC;COSMIC;GDSC;CCLE	1.932	Down-regulation
CMGC_CDK_CDK9_CDK9_ST	P04637	TP53	P50750	CDK9	S127	N131Y	131	Missense	distal	4	no	4.849	4.797	EPSD	ICGC;COSMIC	1.932	Down-regulation
CMGC_CDK_CDK9_CDK9_ST	P04637	TP53	P50750	CDK9	S127	K120M	120	Missense	distal	-7	no	4.849	4.860	EPSD	ICGC;COSMIC	1.932	Up-regulation
CMGC_CDK_CDK9_CDK9_ST	P04637	TP53	P50750	CDK9	S127	K132M	132	Missense	distal	5	no	4.849	4.806	EPSD	ICGC;COSMIC;CCLE	1.932	Down-regulation
CMGC_CDK_CDK9_CDK9_ST	P04637	TP53	P50750	CDK9	S127	M133T	133	Missense	distal	6	no	4.849	4.995	EPSD	ICGC;COSMIC	1.932	Up-regulation
CMGC_CDK_CDK9_CDK9_ST	P04637	TP53	P50750	CDK9	S127	K120R	120	Missense	distal	-7	no	4.849	4.853	EPSD	ICGC;COSMIC	1.932	Up-regulation
CMGC_CDK_CDK9_CDK9_ST	P04637	TP53	P50750	CDK9	S127	C124Y	124	Missense	distal	-3	no	4.849	4.839	EPSD	ICGC;COSMIC	1.932	Down-regulation
CMGC_CDK_CDK9_CDK9_ST	P04637	TP53	P50750	CDK9	T150	R156L	156	Missense	distal	6	no	5.274	5.096	EPSD	ICGC;COSMIC	1.932	Down-regulation
CMGC_CDK_CDK9_CDK9_ST	P04637	TP53	P50750	CDK9	T150	L145Q	145	Missense	distal	-5	no	5.274	5.570	EPSD	ICGC;COSMIC	1.932	Up-regulation
CMGC_CDK_CDK9_CDK9_ST	P04637	TP53	P50750	CDK9	T150	P152R	152	Missense	proximal	2	no	5.274	5.380	EPSD	ICGC;COSMIC	1.932	Up-regulation
CMGC_CDK_CDK9_CDK9_ST	P04637	TP53	P50750	CDK9	T150	G154S	154	Missense	distal	4	no	5.274	5.372	EPSD	ICGC;COSMIC	1.932	Up-regulation
CMGC_CDK_CDK9_CDK9_ST	P04637	TP53	P50750	CDK9	T150	V157A	157	Missense	distal	7	no	5.274	5.289	EPSD	ICGC;COSMIC	1.932	Up-regulation
CMGC_CDK_CDK9_CDK9_ST	P04637	TP53	P50750	CDK9	T150	P151F	151	Missense	proximal	1	no	5.274	0.238	EPSD	ICGC;COSMIC	1.932	Loss
CMGC_CDK_CDK9_CDK9_ST	P04637	TP53	P50750	CDK9	T150	V147G	147	Missense	distal	-3	no	5.274	5.276	EPSD	ICGC;COSMIC;GDSC;CCLE	1.932	Up-regulation
CMGC_CDK_CDK9_CDK9_ST	P04637	TP53	P50750	CDK9	T312	T312I	312	Missense	central	0	yes	2.262	0.000	EPSD	ICGC;COSMIC	1.932	Loss
CMGC_CDK_CDK9_CDK9_ST	P04637	TP53	P50750	CDK9	S313	T312I	312	Missense	proximal	-1	no	2.130	2.110	EPSD	ICGC;COSMIC	1.932	Down-regulation
CMGC_CDK_CDK9_CDK9_ST	P04637	TP53	P50750	CDK9	S315	T312I	312	Missense	distal	-3	no	5.402	5.429	EPSD;PhosphoSitePlus	ICGC;COSMIC	1.932	Up-regulation
CMGC_CDK_CDK9_CDK9_ST	P04637	TP53	P50750	CDK9	S315	P322T	322	Missense	distal	7	no	5.402	5.559	EPSD;PhosphoSitePlus	ICGC	1.932	Up-regulation
CMGC_CDK_CDK9_CDK9_ST	P04637	TP53	P50750	CDK9	S371	T377P	377	Missense	distal	6	no	1.624	1.957	EPSD	ICGC;COSMIC	1.932	Gain
CMGC_CDK_CDK9_CDK9_ST	P04637	TP53	P50750	CDK9	S376	T377P	377	Missense	proximal	1	no	1.885	5.904	EPSD	ICGC;COSMIC	1.932	Gain
CMGC_CDK_CDK9_CDK9_ST	P04637	TP53	P50750	CDK9	S376	R379S	379	Missense	distal	3	no	1.885	2.090	EPSD	ICGC	1.932	Gain
CMGC_CDK_CDK9_CDK9_ST	P04637	TP53	P50750	CDK9	T377	T377P	377	Missense	central	0	yes	2.722	0.000	EPSD	ICGC;COSMIC	1.932	Loss
CMGC_CDK_CDK9_CDK9_ST	P04637	TP53	P50750	CDK9	T377	G374C	374	Missense	distal	-3	no	2.722	2.732	EPSD	ICGC;COSMIC	1.932	Up-regulation
CMGC_CDK_CDK9_CDK9_ST	P04637	TP53	P50750	CDK9	T377	R379S	379	Missense	proximal	2	no	2.722	2.579	EPSD	ICGC	1.932	Down-regulation
CMGC_CDK_CDK9_CDK9_ST	P04637	TP53	P50750	CDK9	T377	R379C	379	Missense	proximal	2	no	2.722	2.786	EPSD	ICGC;COSMIC	1.932	Up-regulation
CMGC_CDK_CDK9_CDK9_ST	P04637	TP53	P50750	CDK9	S378	T377P	377	Missense	proximal	-1	no	2.329	2.341	EPSD	ICGC;COSMIC	1.932	Up-regulation
CMGC_CDK_CDK9_CDK9_ST	P04637	TP53	P50750	CDK9	S378	F385L	385	Missense	distal	7	no	2.329	2.302	EPSD	ICGC;COSMIC	1.932	Down-regulation
CMGC_CDK_CDK9_CDK9_ST	P04637	TP53	P50750	CDK9	S378	G374C	374	Missense	distal	-4	no	2.329	2.281	EPSD	ICGC;COSMIC	1.932	Down-regulation
CMGC_CDK_CDK9_CDK9_ST	P04637	TP53	P50750	CDK9	S378	R379S	379	Missense	proximal	1	no	2.329	2.771	EPSD	ICGC	1.932	Up-regulation
CMGC_CDK_CDK9_CDK9_ST	P04637	TP53	P50750	CDK9	S378	R379C	379	Missense	proximal	1	no	2.329	1.463	EPSD	ICGC;COSMIC	1.932	Loss
CAMK_CAMKL_MELK_MELK_ST	Q14680	MELK	Q14680	MELK	S363	G370V	370	Missense	distal	7	no	137.432	157.582	EPSD	ICGC	155.919	Gain
CAMK_CAMKL_MELK_MELK_ST	Q14680	MELK	Q14680	MELK	S405	P410S	410	Missense	distal	5	no	228.928	238.593	EPSD;PhosphoSitePlus	ICGC;COSMIC	155.919	Up-regulation
CAMK_CAMKL_MELK_MELK_ST	Q14680	MELK	Q14680	MELK	S407	P410S	410	Missense	distal	3	no	217.069	221.018	EPSD;PhosphoSitePlus	ICGC;COSMIC	155.919	Up-regulation
CAMK_CAMKL_MELK_MELK_ST	Q14680	MELK	Q14680	MELK	T409	P410S	410	Missense	proximal	1	no	228.999	225.591	EPSD;PhosphoSitePlus	ICGC;COSMIC	155.919	Down-regulation
CAMK_CAMKL_MELK_MELK_ST	P30305	CDC25B	Q14680	MELK	S67	S67R	67	Missense	central	0	yes	156.366	0.000	EPSD	ICGC	155.919	Loss
CAMK_CAMKL_MELK_MELK_ST	P30305	CDC25B	Q14680	MELK	T69	S67R	67	Missense	proximal	-2	no	172.298	173.548	EPSD	ICGC	155.919	Up-regulation
CAMK_CAMKL_MELK_MELK_ST	P30305	CDC25B	Q14680	MELK	S91	T86M	86	Missense	distal	-5	no	158.041	143.854	EPSD	ICGC;COSMIC	155.919	Loss
CAMK_CAMKL_MELK_MELK_ST	P30305	CDC25B	Q14680	MELK	S169	Q170H	170	Missense	proximal	1	no	213.004	211.271	PhosphoSitePlus;EPSD	ICGC;COSMIC	155.919	Down-regulation
CAMK_CAMKL_MELK_MELK_ST	P30305	CDC25B	Q14680	MELK	S323	M324R	324	Missense	proximal	1	no	225.877	225.225	EPSD;PhosphoSitePlus	ICGC;COSMIC	155.919	Down-regulation
CAMK_CAMKL_MELK_MELK_ST	P30305	CDC25B	Q14680	MELK	S323	R320C	320	Missense	distal	-3	no	225.877	241.607	EPSD;PhosphoSitePlus	ICGC	155.919	Up-regulation
CAMK_CAMKL_MELK_MELK_ST	P30305	CDC25B	Q14680	MELK	S470	E464Q	464	Missense	distal	-6	no	156.622	161.246	EPSD	ICGC;COSMIC	155.919	Up-regulation
CAMK_CAMKL_MELK_MELK_ST	P30305	CDC25B	Q14680	MELK	S563	S563C	563	Missense	central	0	yes	165.448	0.000	EPSD	ICGC;COSMIC	155.919	Loss
CAMK_CAMKL_MELK_MELK_ST	P30305	CDC25B	Q14680	MELK	S563	W564L	564	Missense	proximal	1	no	165.448	163.210	EPSD	ICGC;COSMIC	155.919	Down-regulation
CAMK_CAMKL_MELK_MELK_ST	P23588	EIF4B	Q14680	MELK	S57	S52L	52	Missense	distal	-5	no	170.173	169.004	EPSD	ICGC	155.919	Down-regulation
CAMK_CAMKL_MELK_MELK_ST	P23588	EIF4B	Q14680	MELK	S71	I68V	68	Missense	distal	-3	no	161.869	211.526	EPSD	ICGC;COSMIC	155.919	Up-regulation
CAMK_CAMKL_MELK_MELK_ST	P23588	EIF4B	Q14680	MELK	S276	R279Q	279	Missense	distal	3	no	161.934	167.151	EPSD	ICGC;COSMIC	155.919	Up-regulation
CAMK_CAMKL_MELK_MELK_ST	P23588	EIF4B	Q14680	MELK	S311	D307N	307	Missense	distal	-4	no	165.366	164.680	EPSD	ICGC;COSMIC	155.919	Down-regulation
CAMK_CAMKL_MELK_MELK_ST	P23588	EIF4B	Q14680	MELK	S406	R399Q	399	Missense	distal	-7	no	239.515	234.391	PhosphoSitePlus;EPSD	ICGC;COSMIC	155.919	Down-regulation
CAMK_CAMKL_MELK_MELK_ST	P23588	EIF4B	Q14680	MELK	S406	S406Y	406	Missense	central	0	yes	239.515	0.000	PhosphoSitePlus;EPSD	ICGC	155.919	Loss
STE_STE7_MEK1_MAP2K1_ST	Q13148	TARDBP	Q02750	MAP2K1	S254	S258C	258	Missense	distal	4	no	69.759	70.682	EPSD	ICGC	68.590	Up-regulation
STE_STE7_MEK1_MAP2K1_ST	Q13148	TARDBP	Q02750	MAP2K1	S254	G252C	252	Missense	proximal	-2	no	69.759	70.595	EPSD	ICGC	68.590	Up-regulation
STE_STE7_MEK1_MAP2K1_ST	Q13148	TARDBP	Q02750	MAP2K1	S254	A260V	260	Missense	distal	6	no	69.759	71.962	EPSD	ICGC	68.590	Up-regulation
STE_STE7_MEK1_MAP2K1_ST	P28482	MAPK1	Q02750	MAP2K1	T185	T181K	181	Missense	distal	-4	no	151.746	145.629	PhosphoSitePlus;EPSD	ICGC	68.590	Down-regulation
STE_STE7_MEK1_MAP2K1_ST	P28482	MAPK1	Q02750	MAP2K1	T185	T185K	185	Missense	central	0	yes	151.746	0.000	PhosphoSitePlus;EPSD	ICGC	68.590	Loss
STE_STE7_MEK1_MAP2K1_ST	P28482	MAPK1	Q02750	MAP2K1	T185	W192L	192	Missense	distal	7	no	151.746	152.287	PhosphoSitePlus;EPSD	ICGC;COSMIC	68.590	Up-regulation
STE_STE7_MEK1_MAP2K1_ST	P28482	MAPK1	Q02750	MAP2K1	T190	T185K	185	Missense	distal	-5	no	118.072	117.381	EPSD	ICGC	68.590	Down-regulation
STE_STE7_MEK1_MAP2K1_ST	P28482	MAPK1	Q02750	MAP2K1	T190	W192L	192	Missense	proximal	2	no	118.072	117.146	EPSD	ICGC;COSMIC	68.590	Down-regulation
STE_STE7_MEK1_MAP2K1_ST	P27361	MAPK3	Q02750	MAP2K1	T202	T198I	198	Missense	distal	-4	no	153.714	152.874	EPSD;PhosphoSitePlus	ICGC;COSMIC	68.590	Down-regulation
STE_STE7_MEK1_MAP2K1_ST	P17542	TAL1	Q02750	MAP2K1	S122	A125T	125	Missense	distal	3	no	155.948	156.828	PhosphoSitePlus	ICGC	68.590	Up-regulation
STE_STE7_MEK1_MAP2K1_ST	P49841	GSK3B	Q02750	MAP2K1	T395	S389P	389	Missense	distal	-6	no	73.336	73.497	EPSD	ICGC;COSMIC	68.590	Up-regulation
STE_STE7_MEK1_MAP2K1_ST	P49841	GSK3B	Q02750	MAP2K1	T395	A397T	397	Missense	proximal	2	no	73.336	72.667	EPSD	ICGC;COSMIC	68.590	Down-regulation
STE_STE7_MEK1_MAP2K1_ST	P49841	GSK3B	Q02750	MAP2K1	T395	S398L	398	Missense	distal	3	no	73.336	71.748	EPSD	ICGC;COSMIC	68.590	Down-regulation
STE_STE7_MEK1_MAP2K1_ST	P49841	GSK3B	Q02750	MAP2K1	T402	G406R	406	Missense	distal	4	no	77.413	79.641	EPSD	ICGC;COSMIC	68.590	Up-regulation
STE_STE7_MEK1_MAP2K1_ST	P49841	GSK3B	Q02750	MAP2K1	T402	A397T	397	Missense	distal	-5	no	77.413	77.261	EPSD	ICGC;COSMIC	68.590	Down-regulation
STE_STE7_MEK1_MAP2K1_ST	P49841	GSK3B	Q02750	MAP2K1	T402	S398L	398	Missense	distal	-4	no	77.413	67.734	EPSD	ICGC;COSMIC	68.590	Loss
STE_STE7_MEK1_MAP2K1_ST	P49841	GSK3B	Q02750	MAP2K1	T420	S415T	415	Missense	distal	-5	no	69.454	69.754	EPSD	ICGC;COSMIC	68.590	Up-regulation
STE_STE7_MEK1_MAP2K1_ST	P05787	KRT8	Q02750	MAP2K1	S36	S37C	37	Missense	proximal	1	no	67.114	70.299	EPSD	ICGC;COSMIC	68.590	Gain
STE_STE7_MEK1_MAP2K1_ST	P05787	KRT8	Q02750	MAP2K1	S37	S36W	36	Missense	proximal	-1	no	69.115	64.707	EPSD	ICGC	68.590	Loss
STE_STE7_MEK1_MAP2K1_ST	P05787	KRT8	Q02750	MAP2K1	S37	S37C	37	Missense	central	0	yes	69.115	0.000	EPSD	ICGC;COSMIC	68.590	Loss
STE_STE7_MEK1_MAP2K1_ST	Q00613	HSF1	Q02750	MAP2K1	S237	P239L	239	Missense	proximal	2	no	81.356	82.896	EPSD	ICGC;CCLE	68.590	Up-regulation
STE_STE7_MEK1_MAP2K1_ST	Q00613	HSF1	Q02750	MAP2K1	S444	A437S	437	Missense	distal	-7	no	66.039	69.467	EPSD	ICGC;COSMIC	68.590	Gain
STE_STE7_MEK1_MAP2K1_ST	Q00613	HSF1	Q02750	MAP2K1	S529	A523V	523	Missense	distal	-6	no	85.046	84.878	EPSD	ICGC;COSMIC	68.590	Down-regulation
AGC_GRK_GRK_GRK4_ST	P32298	GRK4	P32298	GRK4	S10	V7A	7	Missense	distal	-3	no	15.694	15.503	EPSD;PhosphoSitePlus	ICGC	10.085	Down-regulation
AGC_GRK_GRK_GRK4_ST	P32298	GRK4	P32298	GRK4	S139	A142V	142	Missense	distal	3	no	17.260	17.330	EPSD;PhosphoSitePlus	ICGC;COSMIC	10.085	Up-regulation
AGC_GRK_GRK_GRK4_ST	P32298	GRK4	P32298	GRK4	S244	K241E	241	Missense	distal	-3	no	17.613	17.500	EPSD;PhosphoSitePlus	ICGC;COSMIC	10.085	Down-regulation
AGC_GRK_GRK_GRK4_ST	P32298	GRK4	P32298	GRK4	T426	K431N	431	Missense	distal	5	no	17.615	17.863	EPSD;PhosphoSitePlus	ICGC;COSMIC	10.085	Up-regulation
AGC_GRK_GRK_GRK4_ST	P32298	GRK4	P32298	GRK4	S430	K431N	431	Missense	proximal	1	no	17.962	16.025	EPSD;PhosphoSitePlus	ICGC;COSMIC	10.085	Down-regulation
AGC_GRK_GRK_GRK4_ST	P32298	GRK4	P32298	GRK4	S485	I481M	481	Missense	distal	-4	no	19.229	19.136	EPSD;PhosphoSitePlus	ICGC;COSMIC	10.085	Down-regulation
AGC_GRK_GRK_GRK4_ST	P32298	GRK4	P32298	GRK4	S485	V486A	486	Missense	proximal	1	no	19.229	18.302	EPSD;PhosphoSitePlus	ICGC;COSMIC	10.085	Down-regulation
AGC_GRK_GRK_GRK4_ST	P30411	BDKRB2	P32298	GRK4	S366	G368V	368	Missense	proximal	2	no	17.238	16.863	PhosphoSitePlus;EPSD	ICGC	10.085	Down-regulation
AGC_GRK_GRK_GRK4_ST	P30411	BDKRB2	P32298	GRK4	S366	I361F	361	Missense	distal	-5	no	17.238	17.425	PhosphoSitePlus;EPSD	ICGC;COSMIC	10.085	Up-regulation
AGC_GRK_GRK_GRK4_ST	P30411	BDKRB2	P32298	GRK4	S366	M367I	367	Missense	proximal	1	no	17.238	17.398	PhosphoSitePlus;EPSD	ICGC;COSMIC	10.085	Up-regulation
AGC_GRK_GRK_GRK4_ST	P30411	BDKRB2	P32298	GRK4	S373	R378L	378	Missense	distal	5	no	15.602	15.690	EPSD;PhosphoSitePlus	ICGC;COSMIC	10.085	Up-regulation
AGC_GRK_GRK_GRK4_ST	P30411	BDKRB2	P32298	GRK4	S373	G368V	368	Missense	distal	-5	no	15.602	15.239	EPSD;PhosphoSitePlus	ICGC	10.085	Down-regulation
AGC_GRK_GRK_GRK4_ST	P30411	BDKRB2	P32298	GRK4	S373	V376L	376	Missense	distal	3	no	15.602	15.506	EPSD;PhosphoSitePlus	ICGC	10.085	Down-regulation
AGC_GRK_GRK_GRK4_ST	P30411	BDKRB2	P32298	GRK4	S373	M367I	367	Missense	distal	-6	no	15.602	16.162	EPSD;PhosphoSitePlus	ICGC;COSMIC	10.085	Up-regulation
AGC_GRK_GRK_GRK4_ST	P30411	BDKRB2	P32298	GRK4	S373	R378H	378	Missense	distal	5	no	15.602	15.794	EPSD;PhosphoSitePlus	ICGC;COSMIC	10.085	Up-regulation
AGC_GRK_GRK_GRK4_ST	P30411	BDKRB2	P32298	GRK4	S375	R378L	378	Missense	distal	3	no	14.245	14.343	EPSD;PhosphoSitePlus	ICGC;COSMIC	10.085	Up-regulation
AGC_GRK_GRK_GRK4_ST	P30411	BDKRB2	P32298	GRK4	S375	G368V	368	Missense	distal	-7	no	14.245	14.498	EPSD;PhosphoSitePlus	ICGC	10.085	Up-regulation
AGC_GRK_GRK_GRK4_ST	P30411	BDKRB2	P32298	GRK4	S375	V376L	376	Missense	proximal	1	no	14.245	14.063	EPSD;PhosphoSitePlus	ICGC	10.085	Down-regulation
AGC_GRK_GRK_GRK4_ST	P30411	BDKRB2	P32298	GRK4	S375	R378H	378	Missense	distal	3	no	14.245	14.052	EPSD;PhosphoSitePlus	ICGC;COSMIC	10.085	Down-regulation
AGC_GRK_GRK_GRK4_ST	P30411	BDKRB2	P32298	GRK4	S375	K382T	382	Missense	distal	7	no	14.245	14.186	EPSD;PhosphoSitePlus	ICGC	10.085	Down-regulation
CAMK_CAMKL_QIK_SIK2_ST	P27986	PIK3R1	Q9H0K1	SIK2	S43	S36G	36	Missense	distal	-7	no	1.583	1.504	EPSD	ICGC;COSMIC	1.318	Down-regulation
CAMK_CAMKL_QIK_SIK2_ST	P27986	PIK3R1	Q9H0K1	SIK2	S43	S43R	43	Missense	central	0	yes	1.583	0.000	EPSD	ICGC;COSMIC	1.318	Loss
CAMK_CAMKL_QIK_SIK2_ST	P27986	PIK3R1	Q9H0K1	SIK2	S147	R151L	151	Missense	distal	4	no	1.232	1.472	EPSD	ICGC;COSMIC	1.318	Gain
CAMK_CAMKL_QIK_SIK2_ST	P27986	PIK3R1	Q9H0K1	SIK2	S154	R151L	151	Missense	distal	-3	no	2.370	2.325	PhosphoSitePlus;EPSD	ICGC;COSMIC	1.318	Down-regulation
CAMK_CAMKL_QIK_SIK2_ST	P27986	PIK3R1	Q9H0K1	SIK2	S154	R151C	151	Missense	distal	-3	no	2.370	2.277	PhosphoSitePlus;EPSD	ICGC;COSMIC	1.318	Down-regulation
CAMK_CAMKL_QIK_SIK2_ST	P27986	PIK3R1	Q9H0K1	SIK2	S156	R151L	151	Missense	distal	-5	no	1.570	1.638	EPSD	ICGC;COSMIC	1.318	Up-regulation
CAMK_CAMKL_QIK_SIK2_ST	P27986	PIK3R1	Q9H0K1	SIK2	S156	R151C	151	Missense	distal	-5	no	1.570	1.510	EPSD	ICGC;COSMIC	1.318	Down-regulation
CAMK_CAMKL_QIK_SIK2_ST	P27986	PIK3R1	Q9H0K1	SIK2	S208	E212D	212	Missense	distal	4	no	1.448	1.323	EPSD	ICGC;COSMIC	1.318	Down-regulation
CAMK_CAMKL_QIK_SIK2_ST	P27986	PIK3R1	Q9H0K1	SIK2	S280	F275L	275	Missense	distal	-5	no	1.300	1.428	EPSD	ICGC;COSMIC	1.318	Gain
CAMK_CAMKL_QIK_SIK2_ST	Q9H0K1	SIK2	Q9H0K1	SIK2	S342	R336C	336	Missense	distal	-6	no	1.460	1.525	EPSD	ICGC;COSMIC	1.318	Up-regulation
CAMK_CAMKL_QIK_SIK2_ST	Q9H0K1	SIK2	Q9H0K1	SIK2	S342	R336L	336	Missense	distal	-6	no	1.460	1.522	EPSD	ICGC	1.318	Up-regulation
CAMK_CAMKL_QIK_SIK2_ST	Q9H0K1	SIK2	Q9H0K1	SIK2	S342	V346L	346	Missense	distal	4	no	1.460	1.551	EPSD	ICGC	1.318	Up-regulation
CAMK_CAMKL_QIK_SIK2_ST	Q9H0K1	SIK2	Q9H0K1	SIK2	S343	R336C	336	Missense	distal	-7	no	2.296	2.254	EPSD;PhosphoSitePlus	ICGC;COSMIC	1.318	Down-regulation
CAMK_CAMKL_QIK_SIK2_ST	Q9H0K1	SIK2	Q9H0K1	SIK2	S343	R336L	336	Missense	distal	-7	no	2.296	2.271	EPSD;PhosphoSitePlus	ICGC	1.318	Down-regulation
CAMK_CAMKL_QIK_SIK2_ST	Q9H0K1	SIK2	Q9H0K1	SIK2	S343	V346L	346	Missense	distal	3	no	2.296	2.290	EPSD;PhosphoSitePlus	ICGC	1.318	Down-regulation
CAMK_CAMKL_QIK_SIK2_ST	Q9H0K1	SIK2	Q9H0K1	SIK2	S358	R353C	353	Missense	distal	-5	no	2.172	2.112	EPSD;PhosphoSitePlus	ICGC	1.318	Down-regulation
CAMK_CAMKL_QIK_SIK2_ST	Q9H0K1	SIK2	Q9H0K1	SIK2	S445	S445I	445	Missense	central	0	yes	1.318	0.000	EPSD	ICGC	1.318	Loss
CAMK_CAMKL_QIK_SIK2_ST	Q9H0K1	SIK2	Q9H0K1	SIK2	S451	S445I	445	Missense	distal	-6	no	1.283	1.366	EPSD	ICGC	1.318	Gain
CAMK_CAMKL_QIK_SIK2_ST	Q9H0K1	SIK2	Q9H0K1	SIK2	S486	R481I	481	Missense	distal	-5	no	1.429	1.410	EPSD	ICGC	1.318	Down-regulation
CAMK_CAMKL_QIK_SIK2_ST	Q9H0K1	SIK2	Q9H0K1	SIK2	S512	M519I	519	Missense	distal	7	no	1.363	1.383	EPSD	ICGC;COSMIC	1.318	Up-regulation
CAMK_CAMKL_QIK_SIK2_ST	Q9H0K1	SIK2	Q9H0K1	SIK2	S512	S515C	515	Missense	distal	3	no	1.363	1.263	EPSD	ICGC	1.318	Loss
CAMK_CAMKL_QIK_SIK2_ST	Q9H0K1	SIK2	Q9H0K1	SIK2	S545	T549A	549	Missense	distal	4	no	1.465	1.585	EPSD	ICGC;COSMIC	1.318	Up-regulation
CAMK_CAMKL_QIK_SIK2_ST	Q9H0K1	SIK2	Q9H0K1	SIK2	S545	P551S	551	Missense	distal	6	no	1.465	1.402	EPSD	ICGC;COSMIC	1.318	Down-regulation
CAMK_CAMKL_QIK_SIK2_ST	Q9H0K1	SIK2	Q9H0K1	SIK2	S545	R547H	547	Missense	proximal	2	no	1.465	1.457	EPSD	ICGC;COSMIC;CCLE	1.318	Down-regulation
CAMK_CAMKL_QIK_SIK2_ST	Q15078	CDK5R1	Q9H0K1	SIK2	S8	R12L	12	Missense	distal	4	no	1.277	1.517	EPSD	ICGC;COSMIC	1.318	Gain
CAMK_CAMKL_QIK_SIK2_ST	Q15078	CDK5R1	Q9H0K1	SIK2	S263	L262P	262	Missense	proximal	-1	no	1.333	1.309	EPSD	ICGC;COSMIC	1.318	Loss
CAMK_CAMKL_QIK_SIK2_ST	Q15078	CDK5R1	Q9H0K1	SIK2	S263	W258L	258	Missense	distal	-5	no	1.333	1.415	EPSD	ICGC;COSMIC	1.318	Up-regulation
CAMK_CAMKL_QIK_SIK2_ST	Q15078	CDK5R1	Q9H0K1	SIK2	S263	L267R	267	Missense	distal	4	no	1.333	1.094	EPSD	ICGC;COSMIC	1.318	Loss
CAMK_CAMKL_QIK_SIK2_ST	Q15078	CDK5R1	Q9H0K1	SIK2	S263	S269I	269	Missense	distal	6	no	1.333	1.249	EPSD	ICGC;COSMIC	1.318	Loss
CAMK_CAMKL_QIK_SIK2_ST	Q9BV73	CEP250	Q9H0K1	SIK2	S45	K43N	43	Missense	proximal	-2	no	1.457	1.421	EPSD	ICGC	1.318	Down-regulation
CAMK_CAMKL_QIK_SIK2_ST	Q9BV73	CEP250	Q9H0K1	SIK2	S331	A334S	334	Missense	distal	3	no	1.454	1.424	EPSD	ICGC	1.318	Down-regulation
CAMK_CAMKL_QIK_SIK2_ST	Q9BV73	CEP250	Q9H0K1	SIK2	S460	E466D	466	Missense	distal	6	no	1.330	1.273	EPSD	ICGC;COSMIC	1.318	Loss
CAMK_CAMKL_QIK_SIK2_ST	Q9BV73	CEP250	Q9H0K1	SIK2	S462	E466D	466	Missense	distal	4	no	1.338	1.212	EPSD	ICGC;COSMIC	1.318	Loss
CAMK_CAMKL_QIK_SIK2_ST	Q9BV73	CEP250	Q9H0K1	SIK2	S576	A569V	569	Missense	distal	-7	no	1.774	1.753	EPSD	ICGC;COSMIC;GDSC	1.318	Down-regulation
CAMK_CAMKL_QIK_SIK2_ST	Q9BV73	CEP250	Q9H0K1	SIK2	S576	A573S	573	Missense	distal	-3	no	1.774	1.758	EPSD	ICGC	1.318	Down-regulation
CAMK_CAMKL_QIK_SIK2_ST	Q9BV73	CEP250	Q9H0K1	SIK2	S583	E590K	590	Missense	distal	7	no	1.382	1.347	EPSD	ICGC;COSMIC	1.318	Down-regulation
CAMK_CAMKL_QIK_SIK2_ST	Q9BV73	CEP250	Q9H0K1	SIK2	S1295	Q1291H	1291	Missense	distal	-4	no	1.387	1.384	EPSD	ICGC	1.318	Down-regulation
CAMK_CAMKL_QIK_SIK2_ST	Q9BV73	CEP250	Q9H0K1	SIK2	S1372	E1379Q	1379	Missense	distal	7	no	1.347	1.316	EPSD	ICGC	1.318	Loss
CAMK_CAMKL_QIK_SIK2_ST	Q9BV73	CEP250	Q9H0K1	SIK2	S1386	R1385Q	1385	Missense	proximal	-1	no	1.304	1.344	EPSD	ICGC	1.318	Gain
CAMK_CAMKL_QIK_SIK2_ST	Q9BV73	CEP250	Q9H0K1	SIK2	S1386	R1385W	1385	Missense	proximal	-1	no	1.304	1.321	EPSD	ICGC	1.318	Gain
CAMK_CAMKL_QIK_SIK2_ST	Q9BV73	CEP250	Q9H0K1	SIK2	S2095	Q2100H	2100	Missense	distal	5	no	1.453	1.527	EPSD	ICGC;COSMIC	1.318	Up-regulation
CAMK_CAMKL_QIK_SIK2_ST	Q9UQL6	HDAC5	Q9H0K1	SIK2	S224	S225R	225	Missense	proximal	1	no	1.577	1.576	EPSD	ICGC;COSMIC	1.318	Down-regulation
CMGC_CDK_CDK4_CDK6_ST	P06400	RB1	Q00534	CDK6	T5	A10S	10	Missense	distal	5	no	85.813	86.080	EPSD	ICGC	54.510	Up-regulation
CMGC_CDK_CDK4_CDK6_ST	P06400	RB1	Q00534	CDK6	T5	A11T	11	Missense	distal	6	no	85.813	85.862	EPSD	ICGC;COSMIC	54.510	Up-regulation
CMGC_CDK_CDK4_CDK6_ST	P06400	RB1	Q00534	CDK6	T9	A10S	10	Missense	proximal	1	no	7.463	58.459	EPSD	ICGC	54.510	Gain
CMGC_CDK_CDK4_CDK6_ST	P06400	RB1	Q00534	CDK6	S230	D224E	224	Missense	distal	-6	no	84.487	84.401	EPSD	ICGC;COSMIC	54.510	Down-regulation
CMGC_CDK_CDK4_CDK6_ST	P06400	RB1	Q00534	CDK6	S249	R251L	251	Missense	proximal	2	no	86.151	86.157	EPSD	ICGC	54.510	Up-regulation
CMGC_CDK_CDK4_CDK6_ST	P06400	RB1	Q00534	CDK6	S249	G256C	256	Missense	distal	7	no	86.151	86.200	EPSD	ICGC	54.510	Up-regulation
CMGC_CDK_CDK4_CDK6_ST	P06400	RB1	Q00534	CDK6	T252	R251L	251	Missense	proximal	-1	no	83.890	83.885	EPSD	ICGC	54.510	Down-regulation
CMGC_CDK_CDK4_CDK6_ST	P06400	RB1	Q00534	CDK6	T252	G256C	256	Missense	distal	4	no	83.890	83.856	EPSD	ICGC	54.510	Down-regulation
CMGC_CDK_CDK4_CDK6_ST	P06400	RB1	Q00534	CDK6	S260	A261S	261	Missense	proximal	1	no	5.412	56.408	EPSD	ICGC;COSMIC	54.510	Gain
CMGC_CDK_CDK4_CDK6_ST	P06400	RB1	Q00534	CDK6	T356	Q354H	354	Missense	proximal	-2	no	83.463	83.486	EPSD	ICGC;COSMIC	54.510	Up-regulation
CMGC_CDK_CDK4_CDK6_ST	P06400	RB1	Q00534	CDK6	S567	L572I	572	Missense	distal	5	no	83.870	83.995	EPSD	ICGC;COSMIC	54.510	Up-regulation
CMGC_CDK_CDK4_CDK6_ST	P06400	RB1	Q00534	CDK6	S567	D571Y	571	Missense	distal	4	no	83.870	83.825	EPSD	ICGC	54.510	Down-regulation
CMGC_CDK_CDK4_CDK6_ST	P06400	RB1	Q00534	CDK6	S567	W563L	563	Missense	distal	-4	no	83.870	83.790	EPSD	ICGC	54.510	Down-regulation
CMGC_CDK_CDK4_CDK6_ST	P06400	RB1	Q00534	CDK6	S567	A562P	562	Missense	distal	-5	no	83.870	83.702	EPSD	ICGC;COSMIC;GDSC;CCLE	54.510	Down-regulation
CMGC_CDK_CDK4_CDK6_ST	P06400	RB1	Q00534	CDK6	S567	L564F	564	Missense	distal	-3	no	83.870	83.861	EPSD	ICGC	54.510	Down-regulation
CMGC_CDK_CDK4_CDK6_ST	P06400	RB1	Q00534	CDK6	S780	P783L	783	Missense	distal	3	no	87.105	84.929	PhosphoSitePlus;EPSD	ICGC	54.510	Down-regulation
CMGC_CDK_CDK4_CDK6_ST	P06400	RB1	Q00534	CDK6	S788	P783L	783	Missense	distal	-5	no	88.702	88.950	EPSD;PhosphoSitePlus	ICGC	54.510	Up-regulation
CMGC_CDK_CDK4_CDK6_ST	P06400	RB1	Q00534	CDK6	S794	L797S	797	Missense	distal	3	no	54.322	56.831	EPSD	ICGC;COSMIC	54.510	Gain
CMGC_CDK_CDK4_CDK6_ST	P06400	RB1	Q00534	CDK6	S795	L797S	797	Missense	proximal	2	no	86.408	86.325	EPSD;PhosphoSitePlus	ICGC;COSMIC	54.510	Down-regulation
CMGC_CDK_CDK4_CDK6_ST	P06400	RB1	Q00534	CDK6	S795	G801E	801	Missense	distal	6	no	86.408	86.424	EPSD;PhosphoSitePlus	ICGC	54.510	Up-regulation
CMGC_CDK_CDK4_CDK6_ST	P06400	RB1	Q00534	CDK6	S807	G801E	801	Missense	distal	-6	no	90.350	90.284	EPSD;PhosphoSitePlus	ICGC	54.510	Down-regulation
CMGC_CDK_CDK4_CDK6_ST	P06400	RB1	Q00534	CDK6	T841	S838L	838	Missense	distal	-3	no	57.504	57.656	EPSD	ICGC;COSMIC	54.510	Up-regulation
CMGC_CDK_CDK4_CDK6_ST	Q08999	RBL2	Q00534	CDK6	S8	P10L	10	Missense	proximal	2	no	85.035	85.124	EPSD	ICGC;COSMIC	54.510	Up-regulation
CMGC_CDK_CDK4_CDK6_ST	Q08999	RBL2	Q00534	CDK6	S8	P14L	14	Missense	distal	6	no	85.035	84.967	EPSD	ICGC	54.510	Down-regulation
CMGC_CDK_CDK4_CDK6_ST	Q08999	RBL2	Q00534	CDK6	S40	E39K	39	Missense	proximal	-1	no	86.652	86.665	EPSD	ICGC;COSMIC	54.510	Up-regulation
CMGC_CDK_CDK4_CDK6_ST	Q08999	RBL2	Q00534	CDK6	S40	A38S	38	Missense	proximal	-2	no	86.652	86.518	EPSD	ICGC	54.510	Down-regulation
CMGC_CDK_CDK4_CDK6_ST	Q08999	RBL2	Q00534	CDK6	S40	Q46K	46	Missense	distal	6	no	86.652	86.676	EPSD	ICGC;COSMIC	54.510	Up-regulation
CMGC_CDK_CDK4_CDK6_ST	Q08999	RBL2	Q00534	CDK6	S40	P36L	36	Missense	distal	-4	no	86.652	85.584	EPSD	ICGC;COSMIC	54.510	Down-regulation
CMGC_CDK_CDK4_CDK6_ST	Q08999	RBL2	Q00534	CDK6	T42	E39K	39	Missense	distal	-3	no	84.864	84.849	EPSD	ICGC;COSMIC	54.510	Down-regulation
CMGC_CDK_CDK4_CDK6_ST	Q08999	RBL2	Q00534	CDK6	T42	A38S	38	Missense	distal	-4	no	84.864	85.177	EPSD	ICGC	54.510	Up-regulation
CMGC_CDK_CDK4_CDK6_ST	Q08999	RBL2	Q00534	CDK6	T42	Q46K	46	Missense	distal	4	no	84.864	84.777	EPSD	ICGC;COSMIC	54.510	Down-regulation
CMGC_CDK_CDK4_CDK6_ST	Q08999	RBL2	Q00534	CDK6	T42	P36L	36	Missense	distal	-6	no	84.864	85.094	EPSD	ICGC;COSMIC	54.510	Up-regulation
CMGC_CDK_CDK4_CDK6_ST	Q08999	RBL2	Q00534	CDK6	T661	Y667C	667	Missense	distal	6	no	54.740	54.754	EPSD	ICGC;COSMIC	54.510	Up-regulation
CMGC_CDK_CDK4_CDK6_ST	Q08999	RBL2	Q00534	CDK6	S662	Y667C	667	Missense	distal	5	no	83.908	83.916	EPSD	ICGC;COSMIC	54.510	Up-regulation
CMGC_CDK_CDK4_CDK6_ST	Q08999	RBL2	Q00534	CDK6	S662	R669S	669	Missense	distal	7	no	83.908	84.325	EPSD	ICGC	54.510	Up-regulation
CMGC_CDK_CDK4_CDK6_ST	Q08999	RBL2	Q00534	CDK6	S671	Y667C	667	Missense	distal	-4	no	57.064	57.172	EPSD	ICGC;COSMIC	54.510	Up-regulation
CMGC_CDK_CDK4_CDK6_ST	Q08999	RBL2	Q00534	CDK6	S671	S672F	672	Missense	proximal	1	no	57.064	-3.306	EPSD	ICGC	54.510	Loss
CMGC_CDK_CDK4_CDK6_ST	Q08999	RBL2	Q00534	CDK6	S671	R669S	669	Missense	proximal	-2	no	57.064	56.895	EPSD	ICGC	54.510	Down-regulation
CMGC_CDK_CDK4_CDK6_ST	Q08999	RBL2	Q00534	CDK6	S671	P674T	674	Missense	distal	3	no	57.064	56.171	EPSD	ICGC;COSMIC	54.510	Down-regulation
CMGC_CDK_CDK4_CDK6_ST	Q08999	RBL2	Q00534	CDK6	S672	Y667C	667	Missense	distal	-5	no	87.984	87.942	EPSD;PhosphoSitePlus	ICGC;COSMIC	54.510	Down-regulation
CMGC_CDK_CDK4_CDK6_ST	Q08999	RBL2	Q00534	CDK6	S672	S672F	672	Missense	central	0	yes	87.984	0.000	EPSD;PhosphoSitePlus	ICGC	54.510	Loss
CMGC_CDK_CDK4_CDK6_ST	Q08999	RBL2	Q00534	CDK6	S672	R669S	669	Missense	distal	-3	no	87.984	87.848	EPSD;PhosphoSitePlus	ICGC	54.510	Down-regulation
CMGC_CDK_CDK4_CDK6_ST	Q08999	RBL2	Q00534	CDK6	S672	P674T	674	Missense	proximal	2	no	87.984	88.001	EPSD;PhosphoSitePlus	ICGC;COSMIC	54.510	Up-regulation
CMGC_CDK_CDK4_CDK6_ST	Q08999	RBL2	Q00534	CDK6	S688	D691V	691	Missense	distal	3	no	84.753	85.806	EPSD	ICGC;COSMIC	54.510	Up-regulation
CMGC_CDK_CDK4_CDK6_ST	Q08999	RBL2	Q00534	CDK6	S688	G693E	693	Missense	distal	5	no	84.753	84.833	EPSD	ICGC;COSMIC	54.510	Up-regulation
CMGC_CDK_CDK4_CDK6_ST	Q08999	RBL2	Q00534	CDK6	T694	D691V	691	Missense	distal	-3	no	84.290	84.187	EPSD	ICGC;COSMIC	54.510	Down-regulation
CMGC_CDK_CDK4_CDK6_ST	Q08999	RBL2	Q00534	CDK6	T694	P699T	699	Missense	distal	5	no	84.290	84.086	EPSD	ICGC;COSMIC	54.510	Down-regulation
CMGC_CDK_CDK4_CDK6_ST	Q08999	RBL2	Q00534	CDK6	T694	R697C	697	Missense	distal	3	no	84.290	84.580	EPSD	ICGC;COSMIC	54.510	Up-regulation
CMGC_CDK_CDK4_CDK6_ST	Q08999	RBL2	Q00534	CDK6	T694	G693E	693	Missense	proximal	-1	no	84.290	84.308	EPSD	ICGC;COSMIC	54.510	Up-regulation
CMGC_CDK_CDK4_CDK6_ST	Q08999	RBL2	Q00534	CDK6	S952	S952C	952	Missense	central	0	yes	84.898	0.000	EPSD	ICGC;COSMIC	54.510	Loss
CMGC_CDK_CDK4_CDK6_ST	Q08999	RBL2	Q00534	CDK6	S952	D945E	945	Missense	distal	-7	no	84.898	85.382	EPSD	ICGC	54.510	Up-regulation
CMGC_CDK_CDK4_CDK6_ST	Q08999	RBL2	Q00534	CDK6	S1035	A1031G	1031	Missense	distal	-4	no	86.166	86.125	EPSD;PhosphoSitePlus	ICGC;COSMIC	54.510	Down-regulation
CMGC_CDK_CDK4_CDK6_ST	Q08050	FOXM1	Q00534	CDK6	T3	R6C	6	Missense	distal	3	no	54.355	54.645	EPSD	ICGC;COSMIC	54.510	Gain
CMGC_CDK_CDK4_CDK6_ST	Q08050	FOXM1	Q00534	CDK6	S4	R6C	6	Missense	proximal	2	no	83.217	83.206	EPSD	ICGC;COSMIC	54.510	Down-regulation
CMGC_CDK_CDK4_CDK6_ST	Q08050	FOXM1	Q00534	CDK6	S35	S41C	41	Missense	distal	6	no	86.767	86.729	EPSD	ICGC;COSMIC	54.510	Down-regulation
CMGC_CDK_CDK4_CDK6_ST	Q08050	FOXM1	Q00534	CDK6	S191	R198C	198	Missense	distal	7	no	54.784	54.835	EPSD	ICGC;COSMIC	54.510	Up-regulation
CMGC_CDK_CDK4_CDK6_ST	Q08050	FOXM1	Q00534	CDK6	S331	P335T	335	Missense	distal	4	no	83.521	83.593	EPSD	ICGC	54.510	Up-regulation
CMGC_CDK_CDK4_CDK6_ST	Q08050	FOXM1	Q00534	CDK6	S331	P335S	335	Missense	distal	4	no	83.521	83.605	EPSD	ICGC	54.510	Up-regulation
CMGC_CDK_CDK4_CDK6_ST	Q08050	FOXM1	Q00534	CDK6	S505	P509T	509	Missense	distal	4	no	57.402	57.473	EPSD	ICGC;COSMIC	54.510	Up-regulation
CMGC_CDK_CDK4_CDK6_ST	Q08050	FOXM1	Q00534	CDK6	S508	P509T	509	Missense	proximal	1	no	88.172	19.565	EPSD;PhosphoSitePlus	ICGC;COSMIC	54.510	Loss
CMGC_CDK_CDK4_CDK6_ST	Q08050	FOXM1	Q00534	CDK6	T510	P509T	509	Missense	proximal	-1	no	86.373	86.340	PhosphoSitePlus;EPSD	ICGC;COSMIC	54.510	Down-regulation
CMGC_CDK_CDK4_CDK6_ST	Q08050	FOXM1	Q00534	CDK6	T627	G634R	634	Missense	distal	7	no	88.014	88.013	EPSD;PhosphoSitePlus	ICGC	54.510	Down-regulation
CMGC_CDK_CDK4_CDK6_ST	Q08050	FOXM1	Q00534	CDK6	S638	G634R	634	Missense	distal	-4	no	84.644	84.524	EPSD	ICGC	54.510	Down-regulation
CMGC_CDK_CDK4_CDK6_ST	P38936	CDKN1A	Q00534	CDK6	T57	D52N	52	Missense	distal	-5	no	84.771	84.669	EPSD	ICGC;COSMIC	54.510	Down-regulation
CMGC_CDK_CDK4_CDK6_ST	P38936	CDKN1A	Q00534	CDK6	T57	E56D	56	Missense	proximal	-1	no	84.771	84.739	EPSD	ICGC	54.510	Down-regulation
CMGC_CDK_CDK4_CDK6_ST	P38936	CDKN1A	Q00534	CDK6	T57	F51V	51	Missense	distal	-6	no	84.771	84.705	EPSD	ICGC;COSMIC	54.510	Down-regulation
CMGC_CDK_CDK4_CDK6_ST	P38936	CDKN1A	Q00534	CDK6	S130	P131T	131	Missense	proximal	1	no	85.601	16.994	PhosphoSitePlus	ICGC;COSMIC	54.510	Loss
CMGC_CDK_CDK4_CDK6_ST	P38936	CDKN1A	Q00534	CDK6	S130	P131Q	131	Missense	proximal	1	no	85.601	3.309	PhosphoSitePlus	ICGC;COSMIC	54.510	Loss
CMGC_CDK_CDK4_CDK6_ST	P38936	CDKN1A	Q00534	CDK6	S130	G129W	129	Missense	proximal	-1	no	85.601	85.617	PhosphoSitePlus	ICGC;COSMIC	54.510	Up-regulation
CMGC_CDK_CDK4_CDK6_ST	P38936	CDKN1A	Q00534	CDK6	T145	R143L	143	Missense	proximal	-2	no	54.973	54.991	EPSD	ICGC	54.510	Up-regulation
CMGC_CDK_CDK4_CDK6_ST	P38936	CDKN1A	Q00534	CDK6	T145	R142Q	142	Missense	distal	-3	no	54.973	54.966	EPSD	ICGC	54.510	Down-regulation
CMGC_CDK_CDK4_CDK6_ST	P38936	CDKN1A	Q00534	CDK6	T145	R140Q	140	Missense	distal	-5	no	54.973	54.927	EPSD	ICGC;COSMIC	54.510	Down-regulation
CMGC_CDK_CDK4_CDK6_ST	Q01196	RUNX1	Q00534	CDK6	S21	M25V	25	Missense	distal	4	no	84.268	84.234	EPSD	ICGC	54.510	Down-regulation
CMGC_CDK_CDK4_CDK6_ST	Q01196	RUNX1	Q00534	CDK6	S361	P359L	359	Missense	proximal	-2	no	54.276	54.517	EPSD	ICGC;COSMIC	54.510	Gain
CMGC_CDK_CDK4_CDK6_ST	Q96KS0	EGLN2	Q00534	CDK6	S74	R77L	77	Missense	distal	3	no	84.198	84.137	EPSD	ICGC;COSMIC	54.510	Down-regulation
CMGC_CDK_CDK4_CDK6_ST	Q96KS0	EGLN2	Q00534	CDK6	S130	D127G	127	Missense	distal	-3	no	85.564	85.550	PhosphoSitePlus	ICGC;COSMIC	54.510	Down-regulation
CMGC_CDK_CDK4_CDK6_ST	Q96KS0	EGLN2	Q00534	CDK6	S130	P129S	129	Missense	proximal	-1	no	85.564	85.553	PhosphoSitePlus	ICGC	54.510	Down-regulation
CMGC_CDK_CDK4_CDK6_ST	Q96KS0	EGLN2	Q00534	CDK6	S155	G149C	149	Missense	distal	-6	no	57.175	57.138	EPSD	ICGC	54.510	Down-regulation
CMGC_CDK_CDK4_CDK6_ST	Q96KS0	EGLN2	Q00534	CDK6	S155	G157V	157	Missense	proximal	2	no	57.175	57.130	EPSD	ICGC	54.510	Down-regulation
CMGC_CDK_CDK4_CDK6_ST	P14618	PKM	Q00534	CDK6	S37	D34E	34	Missense	distal	-3	no	85.695	85.607	PhosphoSitePlus	ICGC	54.510	Down-regulation
CMGC_CDK_CDK4_CDK6_ST	P14618	PKM	Q00534	CDK6	S37	P38T	38	Missense	proximal	1	no	85.695	17.087	PhosphoSitePlus	ICGC	54.510	Loss
CMGC_CDK_CDK4_CDK6_ST	P14618	PKM	Q00534	CDK6	T405	E410K	410	Missense	distal	5	no	56.058	56.062	EPSD	ICGC;COSMIC	54.510	Up-regulation
CMGC_CDK_CDK4_CDK6_ST	P21333	FLNA	Q00534	CDK6	S468	P464L	464	Missense	distal	-4	no	84.390	83.322	EPSD	ICGC	54.510	Down-regulation
CMGC_CDK_CDK4_CDK6_ST	P21333	FLNA	Q00534	CDK6	S468	G475C	475	Missense	distal	7	no	84.390	84.440	EPSD	ICGC;COSMIC	54.510	Up-regulation
CMGC_CDK_CDK4_CDK6_ST	P21333	FLNA	Q00534	CDK6	S564	G571A	571	Missense	distal	7	no	84.560	84.644	EPSD	ICGC;COSMIC	54.510	Up-regulation
CMGC_CDK_CDK4_CDK6_ST	P21333	FLNA	Q00534	CDK6	S657	E652K	652	Missense	distal	-5	no	81.950	81.916	EPSD	ICGC;COSMIC	54.510	Down-regulation
CMGC_CDK_CDK4_CDK6_ST	P21333	FLNA	Q00534	CDK6	S657	R655S	655	Missense	proximal	-2	no	81.950	81.781	EPSD	ICGC;COSMIC	54.510	Down-regulation
CMGC_CDK_CDK4_CDK6_ST	P21333	FLNA	Q00534	CDK6	S757	N762D	762	Missense	distal	5	no	84.185	84.066	EPSD	ICGC;COSMIC	54.510	Down-regulation
CMGC_CDK_CDK4_CDK6_ST	P21333	FLNA	Q00534	CDK6	T857	R863Q	863	Missense	distal	6	no	87.210	87.218	EPSD	ICGC;COSMIC	54.510	Up-regulation
CMGC_CDK_CDK4_CDK6_ST	P21333	FLNA	Q00534	CDK6	T857	P861T	861	Missense	distal	4	no	87.210	87.281	EPSD	ICGC;COSMIC	54.510	Up-regulation
CMGC_CDK_CDK4_CDK6_ST	P21333	FLNA	Q00534	CDK6	T857	T859N	859	Missense	proximal	2	no	87.210	87.263	EPSD	ICGC;COSMIC	54.510	Up-regulation
CMGC_CDK_CDK4_CDK6_ST	P21333	FLNA	Q00534	CDK6	S860	R863Q	863	Missense	distal	3	no	83.018	82.961	EPSD	ICGC;COSMIC	54.510	Down-regulation
CMGC_CDK_CDK4_CDK6_ST	P21333	FLNA	Q00534	CDK6	S860	P861T	861	Missense	proximal	1	no	83.018	14.411	EPSD	ICGC;COSMIC	54.510	Loss
CMGC_CDK_CDK4_CDK6_ST	P21333	FLNA	Q00534	CDK6	S860	T859N	859	Missense	proximal	-1	no	83.018	82.976	EPSD	ICGC;COSMIC	54.510	Down-regulation
CMGC_CDK_CDK4_CDK6_ST	P21333	FLNA	Q00534	CDK6	T938	Y933F	933	Missense	distal	-5	no	83.439	83.427	EPSD	ICGC	54.510	Down-regulation
CMGC_CDK_CDK4_CDK6_ST	P21333	FLNA	Q00534	CDK6	T938	Q941K	941	Missense	distal	3	no	83.439	84.672	EPSD	ICGC;COSMIC	54.510	Up-regulation
CMGC_CDK_CDK4_CDK6_ST	P21333	FLNA	Q00534	CDK6	T938	N931K	931	Missense	distal	-7	no	83.439	83.705	EPSD	ICGC	54.510	Up-regulation
CMGC_CDK_CDK4_CDK6_ST	P21333	FLNA	Q00534	CDK6	S959	P955H	955	Missense	distal	-4	no	86.374	85.350	EPSD	ICGC;COSMIC	54.510	Down-regulation
CMGC_CDK_CDK4_CDK6_ST	P21333	FLNA	Q00534	CDK6	S959	G953V	953	Missense	distal	-6	no	86.374	86.286	EPSD	ICGC;COSMIC	54.510	Down-regulation
CMGC_CDK_CDK4_CDK6_ST	P21333	FLNA	Q00534	CDK6	S1055	P1056H	1056	Missense	proximal	1	no	86.895	-6.231	EPSD	ICGC;COSMIC	54.510	Loss
CMGC_CDK_CDK4_CDK6_ST	P21333	FLNA	Q00534	CDK6	S1055	V1052M	1052	Missense	distal	-3	no	86.895	86.922	EPSD	ICGC;COSMIC;GDSC;CCLE	54.510	Up-regulation
CMGC_CDK_CDK4_CDK6_ST	P21333	FLNA	Q00534	CDK6	S1055	G1049S	1049	Missense	distal	-6	no	86.895	86.669	EPSD	ICGC;COSMIC	54.510	Down-regulation
CMGC_CDK_CDK4_CDK6_ST	P21333	FLNA	Q00534	CDK6	T1255	A1252V	1252	Missense	distal	-3	no	55.305	55.280	EPSD	ICGC;COSMIC;GDSC;CCLE	54.510	Down-regulation
CMGC_CDK_CDK4_CDK6_ST	P21333	FLNA	Q00534	CDK6	T1322	P1323T	1323	Missense	proximal	1	no	84.151	15.544	EPSD	ICGC;COSMIC	54.510	Loss
CMGC_CDK_CDK4_CDK6_ST	P21333	FLNA	Q00534	CDK6	S1343	V1349M	1349	Missense	distal	6	no	84.864	84.852	EPSD	ICGC;COSMIC	54.510	Down-regulation
CMGC_CDK_CDK4_CDK6_ST	P21333	FLNA	Q00534	CDK6	S1436	G1430S	1430	Missense	distal	-6	no	85.444	85.219	EPSD	ICGC;COSMIC	54.510	Down-regulation
CMGC_CDK_CDK4_CDK6_ST	P21333	FLNA	Q00534	CDK6	S1459	R1464S	1464	Missense	distal	5	no	84.005	84.336	EPSD;PhosphoSitePlus	ICGC	54.510	Up-regulation
CMGC_CDK_CDK4_CDK6_ST	P21333	FLNA	Q00534	CDK6	T1475	Q1472K	1472	Missense	distal	-3	no	54.962	54.911	EPSD	ICGC	54.510	Down-regulation
CMGC_CDK_CDK4_CDK6_ST	P21333	FLNA	Q00534	CDK6	T1475	P1482Q	1482	Missense	distal	7	no	54.962	54.711	EPSD	ICGC;COSMIC	54.510	Down-regulation
CMGC_CDK_CDK4_CDK6_ST	P21333	FLNA	Q00534	CDK6	S1533	P1531T	1531	Missense	proximal	-2	no	85.451	85.555	EPSD	ICGC	54.510	Up-regulation
CMGC_CDK_CDK4_CDK6_ST	P21333	FLNA	Q00534	CDK6	S1630	G1623V	1623	Missense	distal	-7	no	83.760	84.125	EPSD	ICGC;COSMIC	54.510	Up-regulation
CMGC_CDK_CDK4_CDK6_ST	P21333	FLNA	Q00534	CDK6	S1630	R1633S	1633	Missense	distal	3	no	83.760	86.209	EPSD	ICGC	54.510	Up-regulation
CMGC_CDK_CDK4_CDK6_ST	P21333	FLNA	Q00534	CDK6	S1923	Y1924S	1924	Missense	proximal	1	no	2.953	56.325	EPSD	ICGC;COSMIC	54.510	Gain
CMGC_CDK_CDK4_CDK6_ST	P21333	FLNA	Q00534	CDK6	S1946	R1951C	1951	Missense	distal	5	no	83.946	83.959	EPSD	ICGC;COSMIC	54.510	Up-regulation
CMGC_CDK_CDK4_CDK6_ST	P21333	FLNA	Q00534	CDK6	S2032	S2032R	2032	Missense	central	0	yes	54.592	0.000	EPSD	ICGC;COSMIC	54.510	Loss
CMGC_CDK_CDK4_CDK6_ST	P21333	FLNA	Q00534	CDK6	S2033	S2032R	2032	Missense	proximal	-1	no	85.700	85.622	EPSD	ICGC;COSMIC	54.510	Down-regulation
CMGC_CDK_CDK4_CDK6_ST	P21333	FLNA	Q00534	CDK6	S2319	P2320L	2320	Missense	proximal	1	no	85.345	-11.663	EPSD	ICGC;COSMIC	54.510	Loss
CMGC_CDK_CDK4_CDK6_ST	P21333	FLNA	Q00534	CDK6	S2327	P2320L	2320	Missense	distal	-7	no	84.700	83.554	EPSD	ICGC;COSMIC	54.510	Down-regulation
CMGC_CDK_CDK4_CDK6_ST	P21333	FLNA	Q00534	CDK6	S2370	A2366S	2366	Missense	distal	-4	no	81.913	82.226	EPSD	ICGC;COSMIC	54.510	Up-regulation
CMGC_CDK_CDK4_CDK6_ST	P21333	FLNA	Q00534	CDK6	S2414	P2415L	2415	Missense	proximal	1	no	83.173	-13.834	EPSD	ICGC	54.510	Loss
CMGC_CDK_CDK4_CDK6_ST	P21333	FLNA	Q00534	CDK6	T2599	T2599N	2599	Missense	central	0	yes	83.572	0.000	EPSD	ICGC;COSMIC	54.510	Loss
CMGC_CDK_CDK4_CDK6_ST	P21333	FLNA	Q00534	CDK6	S2640	P2638T	2638	Missense	proximal	-2	no	82.692	82.795	EPSD	ICGC;COSMIC	54.510	Up-regulation
CMGC_CDK_CDK4_CDK6_ST	P46527	CDKN1B	Q00534	CDK6	S10	N8K	8	Missense	proximal	-2	no	83.673	83.636	PhosphoSitePlus;EPSD	ICGC;COSMIC	54.510	Down-regulation
CMGC_CDK_CDK4_CDK6_ST	P46527	CDKN1B	Q00534	CDK6	S178	V184M	184	Missense	distal	6	no	83.718	83.705	EPSD	ICGC;COSMIC	54.510	Down-regulation
CMGC_CDK_CDK4_CDK6_ST	P46527	CDKN1B	Q00534	CDK6	S178	G182C	182	Missense	distal	4	no	83.718	83.684	EPSD	ICGC	54.510	Down-regulation
CMGC_CDK_CDK4_CDK6_ST	P46527	CDKN1B	Q00534	CDK6	S178	G177V	177	Missense	proximal	-1	no	83.718	83.754	EPSD	ICGC	54.510	Up-regulation
CMGC_CDK_CDK4_CDK6_ST	P46527	CDKN1B	Q00534	CDK6	S178	S178F	178	Missense	central	0	yes	83.718	0.000	EPSD	ICGC;COSMIC	54.510	Loss
CMGC_CDK_CDK4_CDK6_ST	P46527	CDKN1B	Q00534	CDK6	T187	V184M	184	Missense	distal	-3	no	84.707	84.734	EPSD;PhosphoSitePlus	ICGC;COSMIC	54.510	Up-regulation
CMGC_CDK_CDK4_CDK6_ST	P46527	CDKN1B	Q00534	CDK6	T187	G192V	192	Missense	distal	5	no	84.707	84.824	EPSD;PhosphoSitePlus	ICGC	54.510	Up-regulation
CMGC_CDK_CDK4_CDK6_ST	P46527	CDKN1B	Q00534	CDK6	T187	G182C	182	Missense	distal	-5	no	84.707	84.651	EPSD;PhosphoSitePlus	ICGC	54.510	Down-regulation
CMGC_CDK_CDK4_CDK6_ST	P46527	CDKN1B	Q00534	CDK6	T187	P191H	191	Missense	distal	4	no	84.707	84.934	EPSD;PhosphoSitePlus	ICGC;COSMIC	54.510	Up-regulation
CMGC_CDK_CDK4_CDK6_ST	Q92879	CELF1	Q00534	CDK6	S129	Q133K	133	Missense	distal	4	no	55.007	54.919	EPSD	ICGC	54.510	Down-regulation
CMGC_CDK_CDK4_CDK6_ST	Q92879	CELF1	Q00534	CDK6	S129	I124V	124	Missense	distal	-5	no	55.007	54.944	EPSD	ICGC;COSMIC	54.510	Down-regulation
CMGC_CDK_CDK4_CDK6_ST	Q92879	CELF1	Q00534	CDK6	S129	R125Q	125	Missense	distal	-4	no	55.007	55.075	EPSD	ICGC;COSMIC	54.510	Up-regulation
CMGC_CDK_CDK4_CDK6_ST	Q92879	CELF1	Q00534	CDK6	S129	F128L	128	Missense	proximal	-1	no	55.007	54.997	EPSD	ICGC;COSMIC	54.510	Down-regulation
CMGC_CDK_CDK4_CDK6_ST	Q92879	CELF1	Q00534	CDK6	S179	Q172K	172	Missense	distal	-7	no	83.022	83.399	EPSD	ICGC	54.510	Up-regulation
CMGC_CDK_CDK4_CDK6_ST	Q92879	CELF1	Q00534	CDK6	S179	V183G	183	Missense	distal	4	no	83.022	83.107	EPSD	ICGC;COSMIC	54.510	Up-regulation
CMGC_CDK_CDK4_CDK6_ST	Q92879	CELF1	Q00534	CDK6	S179	V183L	183	Missense	distal	4	no	83.022	83.092	EPSD	ICGC	54.510	Up-regulation
CMGC_CDK_CDK4_CDK6_ST	Q92879	CELF1	Q00534	CDK6	S179	A186V	186	Missense	distal	7	no	83.022	83.097	EPSD	ICGC;COSMIC	54.510	Up-regulation
CMGC_CDK_CDK4_CDK6_ST	Q92879	CELF1	Q00534	CDK6	T295	S288G	288	Missense	distal	-7	no	55.475	54.656	EPSD	ICGC	54.510	Down-regulation
CMGC_CDK_CDK4_CDK6_ST	Q92879	CELF1	Q00534	CDK6	T295	S299L	299	Missense	distal	4	no	55.475	55.617	EPSD	ICGC;COSMIC	54.510	Up-regulation
CMGC_CDK_CDK4_CDK6_ST	Q92879	CELF1	Q00534	CDK6	S296	S299L	299	Missense	distal	3	no	58.889	56.380	EPSD	ICGC;COSMIC	54.510	Down-regulation
CMGC_CDK_CDK4_CDK6_ST	Q92879	CELF1	Q00534	CDK6	S299	S299L	299	Missense	central	0	yes	57.914	0.000	EPSD	ICGC;COSMIC	54.510	Loss
CMGC_CDK_CDK4_CDK6_ST	Q92879	CELF1	Q00534	CDK6	S300	S299L	299	Missense	proximal	-1	no	86.266	86.183	EPSD	ICGC;COSMIC	54.510	Down-regulation
CMGC_CDK_CDK4_CDK6_ST	Q92879	CELF1	Q00534	CDK6	S302	S299L	299	Missense	distal	-3	no	59.225	59.377	PhosphoSitePlus	ICGC;COSMIC	54.510	Up-regulation
CMGC_CDK_CDK4_CDK6_ST	Q92879	CELF1	Q00534	CDK6	S303	S299L	299	Missense	distal	-4	no	57.817	57.327	EPSD	ICGC;COSMIC	54.510	Down-regulation
CMGC_CDK_CDK4_CDK6_ST	Q92879	CELF1	Q00534	CDK6	S304	S299L	299	Missense	distal	-5	no	55.227	55.432	EPSD	ICGC;COSMIC	54.510	Up-regulation
CMGC_CDK_CDK4_CDK6_ST	Q92879	CELF1	Q00534	CDK6	S305	S299L	299	Missense	distal	-6	no	56.830	57.059	EPSD	ICGC;COSMIC	54.510	Up-regulation
CMGC_CDK_CDK4_CDK6_ST	P06748	NPM1	Q00534	CDK6	S10	D3H	3	Missense	distal	-7	no	80.890	81.063	EPSD	ICGC;COSMIC	54.510	Up-regulation
CMGC_CDK_CDK4_CDK6_ST	P06748	NPM1	Q00534	CDK6	S70	Y67D	67	Missense	distal	-3	no	85.210	85.250	EPSD	ICGC;COSMIC	54.510	Up-regulation
CMGC_CDK_CDK4_CDK6_ST	P06748	NPM1	Q00534	CDK6	S70	E68K	68	Missense	proximal	-2	no	85.210	85.190	EPSD	ICGC;COSMIC	54.510	Down-regulation
CMGC_CDK_CDK4_CDK6_ST	P06748	NPM1	Q00534	CDK6	S70	M65L	65	Missense	distal	-5	no	85.210	85.289	EPSD	ICGC;GDSC;CCLE	54.510	Up-regulation
CMGC_CDK_CDK4_CDK6_ST	P06748	NPM1	Q00534	CDK6	T95	V99F	99	Missense	distal	4	no	84.970	85.046	EPSD	ICGC	54.510	Up-regulation
CMGC_CDK_CDK4_CDK6_ST	P06748	NPM1	Q00534	CDK6	T95	V99L	99	Missense	distal	4	no	84.970	85.040	EPSD	ICGC;COSMIC	54.510	Up-regulation
CMGC_CDK_CDK4_CDK6_ST	P06748	NPM1	Q00534	CDK6	T95	L102F	102	Missense	distal	7	no	84.970	85.028	EPSD	ICGC;COSMIC	54.510	Up-regulation
CMGC_CDK_CDK4_CDK6_ST	P06748	NPM1	Q00534	CDK6	T95	G90R	90	Missense	distal	-5	no	84.970	84.958	EPSD	ICGC;COSMIC	54.510	Down-regulation
CMGC_CDK_CDK4_CDK6_ST	P06748	NPM1	Q00534	CDK6	T95	S88F	88	Missense	distal	-7	no	84.970	84.203	EPSD	ICGC;COSMIC	54.510	Down-regulation
CMGC_CDK_CDK4_CDK6_ST	P06748	NPM1	Q00534	CDK6	T95	V99A	99	Missense	distal	4	no	84.970	85.003	EPSD	ICGC;COSMIC	54.510	Up-regulation
CMGC_CDK_CDK4_CDK6_ST	P06748	NPM1	Q00534	CDK6	T199	R197G	197	Missense	proximal	-2	no	86.828	86.846	PhosphoSitePlus	ICGC;COSMIC	54.510	Up-regulation
CMGC_CDK_CDK4_CDK6_ST	P06748	NPM1	Q00534	CDK6	T199	A204T	204	Missense	distal	5	no	86.828	86.957	PhosphoSitePlus	ICGC;COSMIC	54.510	Up-regulation
CMGC_CDK_CDK4_CDK6_ST	P06748	NPM1	Q00534	CDK6	T199	P200A	200	Missense	proximal	1	no	86.828	6.193	PhosphoSitePlus	ICGC	54.510	Loss
CMGC_CDK_CDK4_CDK6_ST	P06748	NPM1	Q00534	CDK6	S242	D246Y	246	Missense	distal	4	no	56.489	56.444	EPSD	ICGC	54.510	Down-regulation
CMGC_CDK_CDK8_CDK8_ST	Q15797	SMAD1	P49336	CDK8	S187	N180H	180	Missense	distal	-7	no	51.000	50.980	EPSD;PhosphoSitePlus	ICGC;COSMIC	26.151	Down-regulation
CMGC_CDK_CDK8_CDK8_ST	Q15797	SMAD1	P49336	CDK8	S187	P188T	188	Missense	proximal	1	no	51.000	40.415	EPSD;PhosphoSitePlus	ICGC;COSMIC	26.151	Down-regulation
CMGC_CDK_CDK8_CDK8_ST	Q15797	SMAD1	P49336	CDK8	S187	P183S	183	Missense	distal	-4	no	51.000	50.755	EPSD;PhosphoSitePlus	ICGC	26.151	Down-regulation
CMGC_CDK_CDK8_CDK8_ST	Q15797	SMAD1	P49336	CDK8	S195	T202A	202	Missense	distal	7	no	50.921	50.626	PhosphoSitePlus;EPSD	ICGC;COSMIC	26.151	Down-regulation
CMGC_CDK_CDK8_CDK8_ST	Q15797	SMAD1	P49336	CDK8	S195	G197W	197	Missense	proximal	2	no	50.921	49.637	PhosphoSitePlus;EPSD	ICGC;COSMIC	26.151	Down-regulation
CMGC_CDK_CDK8_CDK8_ST	Q15797	SMAD1	P49336	CDK8	S195	P188T	188	Missense	distal	-7	no	50.921	50.948	PhosphoSitePlus;EPSD	ICGC;COSMIC	26.151	Up-regulation
CMGC_CDK_CDK8_CDK8_ST	Q15797	SMAD1	P49336	CDK8	S206	T202A	202	Missense	distal	-4	no	50.529	49.285	EPSD;PhosphoSitePlus	ICGC;COSMIC	26.151	Down-regulation
CMGC_CDK_CDK8_CDK8_ST	Q15797	SMAD1	P49336	CDK8	S321	R319W	319	Missense	proximal	-2	no	27.550	20.672	EPSD	ICGC;COSMIC	26.151	Loss
CMGC_CDK_CDK8_CDK8_ST	Q15797	SMAD1	P49336	CDK8	S321	R328W	328	Missense	distal	7	no	27.550	27.308	EPSD	ICGC;COSMIC	26.151	Down-regulation
CMGC_CDK_CDK8_CDK8_ST	Q15797	SMAD1	P49336	CDK8	S456	P457L	457	Missense	proximal	1	no	28.337	2.483	EPSD	ICGC;COSMIC	26.151	Loss
CMGC_CDK_CDK8_CDK8_ST	P46531	NOTCH1	P49336	CDK8	T535	C537S	537	Missense	proximal	2	no	31.052	30.615	EPSD	ICGC;COSMIC	26.151	Down-regulation
CMGC_CDK_CDK8_CDK8_ST	P46531	NOTCH1	P49336	CDK8	T1861	P1862S	1862	Missense	proximal	1	no	28.750	14.523	EPSD	ICGC	26.151	Loss
CMGC_CDK_CDK8_CDK8_ST	P46531	NOTCH1	P49336	CDK8	T1861	P1862Q	1862	Missense	proximal	1	no	28.750	0.581	EPSD	ICGC;COSMIC	26.151	Loss
CMGC_CDK_CDK8_CDK8_ST	P46531	NOTCH1	P49336	CDK8	S1941	L1948M	1948	Missense	distal	7	no	27.022	27.844	EPSD	ICGC;COSMIC	26.151	Up-regulation
CMGC_CDK_CDK8_CDK8_ST	P46531	NOTCH1	P49336	CDK8	S2136	G2130W	2130	Missense	distal	-6	no	39.195	39.158	EPSD	ICGC;COSMIC	26.151	Down-regulation
CMGC_CDK_CDK8_CDK8_ST	P46531	NOTCH1	P49336	CDK8	S2136	P2138Q	2138	Missense	proximal	2	no	39.195	41.327	EPSD	ICGC;COSMIC	26.151	Up-regulation
CMGC_CDK_CDK8_CDK8_ST	P46531	NOTCH1	P49336	CDK8	S2141	P2138Q	2138	Missense	distal	-3	no	32.184	31.969	EPSD	ICGC;COSMIC	26.151	Down-regulation
CMGC_CDK_CDK8_CDK8_ST	P46531	NOTCH1	P49336	CDK8	S2162	G2165V	2165	Missense	distal	3	no	27.147	28.387	EPSD	ICGC;COSMIC	26.151	Up-regulation
CMGC_CDK_CDK8_CDK8_ST	P46531	NOTCH1	P49336	CDK8	S2163	G2165V	2165	Missense	proximal	2	no	41.287	39.019	EPSD	ICGC;COSMIC	26.151	Down-regulation
CMGC_CDK_CDK8_CDK8_ST	P46531	NOTCH1	P49336	CDK8	S2215	P2216T	2216	Missense	proximal	1	no	40.600	30.015	EPSD	ICGC	26.151	Down-regulation
CMGC_CDK_CDK8_CDK8_ST	P46531	NOTCH1	P49336	CDK8	S2215	L2218R	2218	Missense	distal	3	no	40.600	43.059	EPSD	ICGC	26.151	Up-regulation
CMGC_CDK_CDK8_CDK8_ST	P46531	NOTCH1	P49336	CDK8	S2221	P2216T	2216	Missense	distal	-5	no	37.631	37.617	EPSD	ICGC	26.151	Down-regulation
CMGC_CDK_CDK8_CDK8_ST	P46531	NOTCH1	P49336	CDK8	S2221	L2218R	2218	Missense	distal	-3	no	37.631	38.050	EPSD	ICGC	26.151	Up-regulation
CMGC_CDK_CDK8_CDK8_ST	P46531	NOTCH1	P49336	CDK8	S2513	P2512L	2512	Missense	proximal	-1	no	42.769	42.564	PhosphoSitePlus;EPSD	ICGC;COSMIC	26.151	Down-regulation
CMGC_CDK_CDK8_CDK8_ST	P46531	NOTCH1	P49336	CDK8	S2513	S2516F	2516	Missense	distal	3	no	42.769	40.416	PhosphoSitePlus;EPSD	ICGC	26.151	Down-regulation
CMGC_CDK_CDK8_CDK8_ST	P46531	NOTCH1	P49336	CDK8	S2513	P2512T	2512	Missense	proximal	-1	no	42.769	42.736	PhosphoSitePlus;EPSD	ICGC;COSMIC	26.151	Down-regulation
CMGC_CDK_CDK8_CDK8_ST	P46531	NOTCH1	P49336	CDK8	S2516	P2512L	2512	Missense	distal	-4	no	48.751	44.864	EPSD;PhosphoSitePlus	ICGC;COSMIC	26.151	Down-regulation
CMGC_CDK_CDK8_CDK8_ST	P46531	NOTCH1	P49336	CDK8	S2516	S2516F	2516	Missense	central	0	yes	48.751	0.000	EPSD;PhosphoSitePlus	ICGC	26.151	Loss
CMGC_CDK_CDK8_CDK8_ST	P46531	NOTCH1	P49336	CDK8	S2516	P2512T	2512	Missense	distal	-4	no	48.751	48.750	EPSD;PhosphoSitePlus	ICGC;COSMIC	26.151	Down-regulation
CMGC_CDK_CDK8_CDK8_ST	P46531	NOTCH1	P49336	CDK8	S2524	P2525Q	2525	Missense	proximal	1	no	35.106	6.937	EPSD	ICGC;COSMIC	26.151	Loss
CMGC_CDK_CDK8_CDK8_ST	P84022	SMAD3	P49336	CDK8	S204	D201N	201	Missense	distal	-3	no	32.440	32.491	EPSD	ICGC	26.151	Up-regulation
CMGC_CDK_CDK8_CDK8_ST	P84022	SMAD3	P49336	CDK8	S208	D201N	201	Missense	distal	-7	no	50.292	50.298	PhosphoSitePlus;EPSD	ICGC	26.151	Up-regulation
CMGC_CDK_CDK8_CDK8_ST	P84022	SMAD3	P49336	CDK8	S213	L219F	219	Missense	distal	6	no	51.172	51.009	EPSD;PhosphoSitePlus	ICGC;COSMIC	26.151	Down-regulation
CMGC_CDK_CDK8_CDK8_ST	P84022	SMAD3	P49336	CDK8	S416	S423T	423	Missense	distal	7	no	27.595	27.889	EPSD	ICGC;COSMIC	26.151	Up-regulation
CMGC_CDK_CDK8_CDK8_ST	P84022	SMAD3	P49336	CDK8	S416	S422F	422	Missense	distal	6	no	27.595	28.313	EPSD	ICGC;COSMIC	26.151	Up-regulation
CMGC_CDK_CDK8_CDK8_ST	P84022	SMAD3	P49336	CDK8	S416	G415V	415	Missense	proximal	-1	no	27.595	28.009	EPSD	ICGC	26.151	Up-regulation
CMGC_CDK_CDK8_CDK8_ST	P84022	SMAD3	P49336	CDK8	S416	S423N	423	Missense	distal	7	no	27.595	27.467	EPSD	ICGC;COSMIC	26.151	Down-regulation
CMGC_CDK_CDK8_CDK8_ST	P84022	SMAD3	P49336	CDK8	S416	L411F	411	Missense	distal	-5	no	27.595	27.862	EPSD	ICGC;COSMIC	26.151	Up-regulation
CMGC_CDK_CDK8_CDK8_ST	P84022	SMAD3	P49336	CDK8	S416	R420S	420	Missense	distal	4	no	27.595	27.592	EPSD	ICGC;COSMIC	26.151	Down-regulation
CMGC_CDK_CDK8_CDK8_ST	P84022	SMAD3	P49336	CDK8	S416	L411I	411	Missense	distal	-5	no	27.595	27.662	EPSD	ICGC;COSMIC	26.151	Up-regulation
CMGC_CDK_CDK8_CDK8_ST	Q01094	E2F1	P49336	CDK8	S121	S121F	121	Missense	central	0	yes	29.253	0.000	EPSD	ICGC;COSMIC;CCLE	26.151	Loss
CMGC_CDK_CDK8_CDK8_ST	Q01094	E2F1	P49336	CDK8	S121	P122L	122	Missense	proximal	1	no	29.253	3.400	EPSD	ICGC	26.151	Loss
CMGC_CDK_CDK8_CDK8_ST	Q01094	E2F1	P49336	CDK8	S307	P308T	308	Missense	proximal	1	no	31.092	20.508	EPSD	ICGC	26.151	Loss
CMGC_CDK_CDK8_CDK8_ST	Q01094	E2F1	P49336	CDK8	S307	G305W	305	Missense	proximal	-2	no	31.092	35.893	EPSD	ICGC;COSMIC	26.151	Up-regulation
CMGC_CDK_CDK8_CDK8_ST	Q01094	E2F1	P49336	CDK8	S307	G305V	305	Missense	proximal	-2	no	31.092	34.381	EPSD	ICGC;COSMIC	26.151	Up-regulation
CMGC_CDK_CDK8_CDK8_ST	Q01094	E2F1	P49336	CDK8	S375	V369M	369	Missense	distal	-6	no	49.538	49.564	PhosphoSitePlus	ICGC	26.151	Up-regulation
CMGC_CDK_CDK8_CDK8_ST	Q01094	E2F1	P49336	CDK8	S403	A408V	408	Missense	distal	5	no	31.917	30.178	EPSD	ICGC;COSMIC	26.151	Down-regulation
CMGC_CDK_CDK8_CDK8_ST	Q01094	E2F1	P49336	CDK8	S403	E397K	397	Missense	distal	-6	no	31.917	31.881	EPSD	ICGC;COSMIC	26.151	Down-regulation
CMGC_CDK_CDK8_CDK8_ST	P51946	CCNH	P49336	CDK8	S5	T12N	12	Missense	distal	7	no	34.219	33.797	PhosphoSitePlus;EPSD	ICGC	26.151	Down-regulation
CMGC_CDK_CDK8_CDK8_ST	P51946	CCNH	P49336	CDK8	S5	H3Q	3	Missense	proximal	-2	no	34.219	21.684	PhosphoSitePlus;EPSD	ICGC	26.151	Loss
CMGC_CDK_CDK8_CDK8_ST	P51946	CCNH	P49336	CDK8	S5	H3N	3	Missense	proximal	-2	no	34.219	31.149	PhosphoSitePlus;EPSD	ICGC	26.151	Down-regulation
CMGC_CDK_CDK8_CDK8_ST	P51946	CCNH	P49336	CDK8	S132	R130W	130	Missense	proximal	-2	no	31.091	24.213	EPSD	ICGC	26.151	Loss
TK_Fak_PTK2_Y	Q9H9S0	NANOG	Q05397	PTK2	Y35	Y35H	35	Missense	central	0	yes	0.000	0.000	PhosphoSitePlus;EPSD	ICGC;COSMIC	0.000	Loss
TK_Fak_PTK2_Y	Q05397	PTK2	Q05397	PTK2	Y251	Y251H	251	Missense	central	0	yes	0.000	0.000	EPSD	ICGC	0.000	Loss
TK_Fak_PTK2_Y	P12814	ACTN1	Q05397	PTK2	Y193	Y193C	193	Missense	central	0	yes	0.000	0.000	EPSD	ICGC;COSMIC	0.000	Loss
TK_Fak_PTK2_Y	Q9Y2X7	GIT1	Q05397	PTK2	Y246	Y246C	246	Missense	central	0	yes	0.000	0.000	EPSD	ICGC;COSMIC	0.000	Loss
AGC_RSK_RSKp90_RPS6KA1_ST	O95071	UBR5	Q15418	RPS6KA1	S115	R122K	122	Missense	distal	7	no	1.788	1.639	EPSD	ICGC;COSMIC	1.787	Loss
AGC_RSK_RSKp90_RPS6KA1_ST	O95071	UBR5	Q15418	RPS6KA1	S115	T119N	119	Missense	distal	4	no	1.788	1.759	EPSD	ICGC	1.787	Loss
AGC_RSK_RSKp90_RPS6KA1_ST	O95071	UBR5	Q15418	RPS6KA1	S115	G116V	116	Missense	proximal	1	no	1.788	1.858	EPSD	ICGC;COSMIC	1.787	Up-regulation
AGC_RSK_RSKp90_RPS6KA1_ST	O95071	UBR5	Q15418	RPS6KA1	S305	R303H	303	Missense	proximal	-2	no	2.894	2.981	EPSD	ICGC;COSMIC	1.787	Up-regulation
AGC_RSK_RSKp90_RPS6KA1_ST	O95071	UBR5	Q15418	RPS6KA1	S305	R303S	303	Missense	proximal	-2	no	2.894	2.960	EPSD	ICGC	1.787	Up-regulation
AGC_RSK_RSKp90_RPS6KA1_ST	O95071	UBR5	Q15418	RPS6KA1	S305	E306A	306	Missense	proximal	1	no	2.894	2.966	EPSD	ICGC;COSMIC	1.787	Up-regulation
AGC_RSK_RSKp90_RPS6KA1_ST	O95071	UBR5	Q15418	RPS6KA1	S636	E643K	643	Missense	distal	7	no	1.931	1.862	EPSD	ICGC;COSMIC	1.787	Down-regulation
AGC_RSK_RSKp90_RPS6KA1_ST	O95071	UBR5	Q15418	RPS6KA1	T1115	G1113W	1113	Missense	proximal	-2	no	1.869	1.808	EPSD	ICGC;COSMIC	1.787	Down-regulation
AGC_RSK_RSKp90_RPS6KA1_ST	O95071	UBR5	Q15418	RPS6KA1	T1115	M1114V	1114	Missense	proximal	-1	no	1.869	1.930	EPSD	ICGC;COSMIC	1.787	Up-regulation
AGC_RSK_RSKp90_RPS6KA1_ST	O95071	UBR5	Q15418	RPS6KA1	S1119	G1113W	1113	Missense	distal	-6	no	2.058	1.483	EPSD	ICGC;COSMIC	1.787	Loss
AGC_RSK_RSKp90_RPS6KA1_ST	O95071	UBR5	Q15418	RPS6KA1	S1119	M1114V	1114	Missense	distal	-5	no	2.058	2.214	EPSD	ICGC;COSMIC	1.787	Up-regulation
AGC_RSK_RSKp90_RPS6KA1_ST	O95071	UBR5	Q15418	RPS6KA1	T1306	T1306K	1306	Missense	central	0	yes	2.726	0.000	EPSD	ICGC	1.787	Loss
AGC_RSK_RSKp90_RPS6KA1_ST	O95071	UBR5	Q15418	RPS6KA1	T1404	G1403C	1403	Missense	proximal	-1	no	3.233	3.183	EPSD	ICGC;COSMIC	1.787	Down-regulation
AGC_RSK_RSKp90_RPS6KA1_ST	O95071	UBR5	Q15418	RPS6KA1	T1404	Q1410K	1410	Missense	distal	6	no	3.233	3.187	EPSD	ICGC;COSMIC	1.787	Down-regulation
AGC_RSK_RSKp90_RPS6KA1_ST	O95071	UBR5	Q15418	RPS6KA1	S1549	Q1544K	1544	Missense	distal	-5	no	3.013	3.081	EPSD	ICGC;COSMIC	1.787	Up-regulation
AGC_RSK_RSKp90_RPS6KA1_ST	O95071	UBR5	Q15418	RPS6KA1	S1776	A1781V	1781	Missense	distal	5	no	1.896	1.980	EPSD	ICGC;COSMIC	1.787	Up-regulation
AGC_RSK_RSKp90_RPS6KA1_ST	O95071	UBR5	Q15418	RPS6KA1	S2241	R2246W	2246	Missense	distal	5	no	2.102	1.916	EPSD	ICGC;COSMIC;GDSC;CCLE	1.787	Down-regulation
AGC_RSK_RSKp90_RPS6KA1_ST	O95071	UBR5	Q15418	RPS6KA1	S2356	R2360L	2360	Missense	distal	4	no	1.849	1.897	EPSD	ICGC;COSMIC	1.787	Up-regulation
AGC_RSK_RSKp90_RPS6KA1_ST	O95071	UBR5	Q15418	RPS6KA1	S2424	L2429I	2429	Missense	distal	5	no	1.932	1.998	EPSD	ICGC	1.787	Up-regulation
AGC_RSK_RSKp90_RPS6KA1_ST	O95071	UBR5	Q15418	RPS6KA1	S2470	D2468E	2468	Missense	proximal	-2	no	2.581	2.557	EPSD	ICGC	1.787	Down-regulation
AGC_RSK_RSKp90_RPS6KA1_ST	O95071	UBR5	Q15418	RPS6KA1	S2470	V2473L	2473	Missense	distal	3	no	2.581	2.665	EPSD	ICGC;COSMIC	1.787	Up-regulation
AGC_RSK_RSKp90_RPS6KA1_ST	Q13164	MAPK7	Q15418	RPS6KA1	S486	R492K	492	Missense	distal	6	no	2.773	2.675	EPSD	ICGC	1.787	Down-regulation
AGC_RSK_RSKp90_RPS6KA1_ST	Q13164	MAPK7	Q15418	RPS6KA1	S496	A501D	501	Missense	distal	5	no	1.849	1.737	PhosphoSitePlus	ICGC;COSMIC	1.787	Loss
AGC_RSK_RSKp90_RPS6KA1_ST	Q13164	MAPK7	Q15418	RPS6KA1	S496	R492K	492	Missense	distal	-4	no	1.849	1.822	PhosphoSitePlus	ICGC	1.787	Down-regulation
AGC_RSK_RSKp90_RPS6KA1_ST	Q13164	MAPK7	Q15418	RPS6KA1	S720	D724Y	724	Missense	distal	4	no	2.079	2.087	EPSD	ICGC	1.787	Up-regulation
AGC_RSK_RSKp90_RPS6KA1_ST	Q13164	MAPK7	Q15418	RPS6KA1	S720	Q721L	721	Missense	proximal	1	no	2.079	2.084	EPSD	ICGC;COSMIC	1.787	Up-regulation
AGC_RSK_RSKp90_RPS6KA1_ST	Q13164	MAPK7	Q15418	RPS6KA1	S720	L717I	717	Missense	distal	-3	no	2.079	1.868	EPSD	ICGC;COSMIC	1.787	Down-regulation
AGC_RSK_RSKp90_RPS6KA1_ST	O60343	TBC1D4	Q15418	RPS6KA1	S44	G42V	42	Missense	proximal	-2	no	2.694	2.662	EPSD	ICGC	1.787	Down-regulation
AGC_RSK_RSKp90_RPS6KA1_ST	O60343	TBC1D4	Q15418	RPS6KA1	S292	T290N	290	Missense	proximal	-2	no	1.869	1.871	EPSD	ICGC;COSMIC	1.787	Up-regulation
AGC_RSK_RSKp90_RPS6KA1_ST	O60343	TBC1D4	Q15418	RPS6KA1	S292	A288S	288	Missense	distal	-4	no	1.869	1.762	EPSD	ICGC;COSMIC	1.787	Loss
AGC_RSK_RSKp90_RPS6KA1_ST	O60343	TBC1D4	Q15418	RPS6KA1	S292	R299Q	299	Missense	distal	7	no	1.869	1.828	EPSD	ICGC;COSMIC;CCLE	1.787	Down-regulation
AGC_RSK_RSKp90_RPS6KA1_ST	O60343	TBC1D4	Q15418	RPS6KA1	T568	N561H	561	Missense	distal	-7	no	1.990	1.994	EPSD;PhosphoSitePlus	ICGC	1.787	Up-regulation
AGC_RSK_RSKp90_RPS6KA1_ST	O60343	TBC1D4	Q15418	RPS6KA1	T568	K562R	562	Missense	distal	-6	no	1.990	1.095	EPSD;PhosphoSitePlus	ICGC	1.787	Loss
AGC_RSK_RSKp90_RPS6KA1_ST	O60343	TBC1D4	Q15418	RPS6KA1	S591	R585G	585	Missense	distal	-6	no	0.897	1.805	EPSD	ICGC	1.787	Gain
AGC_RSK_RSKp90_RPS6KA1_ST	O60343	TBC1D4	Q15418	RPS6KA1	S631	P634L	634	Missense	distal	3	no	2.054	2.119	EPSD	ICGC	1.787	Up-regulation
AGC_RSK_RSKp90_RPS6KA1_ST	O60343	TBC1D4	Q15418	RPS6KA1	S631	Q635K	635	Missense	distal	4	no	2.054	2.082	EPSD	ICGC	1.787	Up-regulation
AGC_RSK_RSKp90_RPS6KA1_ST	O60343	TBC1D4	Q15418	RPS6KA1	S631	S633Y	633	Missense	proximal	2	no	2.054	2.093	EPSD	ICGC;COSMIC	1.787	Up-regulation
AGC_RSK_RSKp90_RPS6KA1_ST	O60343	TBC1D4	Q15418	RPS6KA1	S631	E629K	629	Missense	proximal	-2	no	2.054	2.089	EPSD	ICGC;COSMIC	1.787	Up-regulation
AGC_RSK_RSKp90_RPS6KA1_ST	O60343	TBC1D4	Q15418	RPS6KA1	S702	P706T	706	Missense	distal	4	no	1.790	1.793	EPSD	ICGC;COSMIC	1.787	Up-regulation
AGC_RSK_RSKp90_RPS6KA1_ST	Q92934	BAD	Q15418	RPS6KA1	S34	G35D	35	Missense	proximal	1	no	1.868	1.971	EPSD	ICGC;COSMIC	1.787	Up-regulation
AGC_RSK_RSKp90_RPS6KA1_ST	Q92934	BAD	Q15418	RPS6KA1	S75	R72S	72	Missense	distal	-3	no	3.978	3.574	PhosphoSitePlus	ICGC	1.787	Down-regulation
AGC_RSK_RSKp90_RPS6KA1_ST	Q92934	BAD	Q15418	RPS6KA1	S75	T80K	80	Missense	distal	5	no	3.978	3.877	PhosphoSitePlus	ICGC	1.787	Down-regulation
AGC_RSK_RSKp90_RPS6KA1_ST	Q92934	BAD	Q15418	RPS6KA1	S75	S74G	74	Missense	proximal	-1	no	3.978	4.026	PhosphoSitePlus	ICGC;COSMIC	1.787	Up-regulation
AGC_RSK_RSKp90_RPS6KA1_ST	P19634	SLC9A1	Q15418	RPS6KA1	T42	S49N	49	Missense	distal	7	no	2.718	2.808	EPSD	ICGC	1.787	Up-regulation
AGC_RSK_RSKp90_RPS6KA1_ST	Q8IX03	WWC1	Q15418	RPS6KA1	S141	W135L	135	Missense	distal	-6	no	1.420	1.825	EPSD	ICGC;COSMIC	1.787	Gain
AGC_RSK_RSKp90_RPS6KA1_ST	Q8IX03	WWC1	Q15418	RPS6KA1	S241	A243T	243	Missense	proximal	2	no	1.550	1.841	EPSD	ICGC;COSMIC	1.787	Gain
AGC_RSK_RSKp90_RPS6KA1_ST	Q8IX03	WWC1	Q15418	RPS6KA1	S262	L266V	266	Missense	distal	4	no	1.847	1.759	EPSD	ICGC;COSMIC	1.787	Loss
AGC_RSK_RSKp90_RPS6KA1_ST	Q8IX03	WWC1	Q15418	RPS6KA1	S262	S255Y	255	Missense	distal	-7	no	1.847	1.813	EPSD	ICGC;COSMIC	1.787	Down-regulation
AGC_RSK_RSKp90_RPS6KA1_ST	Q8IX03	WWC1	Q15418	RPS6KA1	S262	S268I	268	Missense	distal	6	no	1.847	1.794	EPSD	ICGC;COSMIC	1.787	Down-regulation
AGC_RSK_RSKp90_RPS6KA1_ST	Q8IX03	WWC1	Q15418	RPS6KA1	S530	P536Q	536	Missense	distal	6	no	2.098	2.110	EPSD	ICGC;COSMIC	1.787	Up-regulation
AGC_RSK_RSKp90_RPS6KA1_ST	Q8IX03	WWC1	Q15418	RPS6KA1	S530	T527I	527	Missense	distal	-3	no	2.098	2.423	EPSD	ICGC;COSMIC	1.787	Up-regulation
AGC_RSK_RSKp90_RPS6KA1_ST	Q8IX03	WWC1	Q15418	RPS6KA1	S530	S535F	535	Missense	distal	5	no	2.098	2.096	EPSD	ICGC	1.787	Down-regulation
AGC_RSK_RSKp90_RPS6KA1_ST	Q8IX03	WWC1	Q15418	RPS6KA1	T532	P536Q	536	Missense	distal	4	no	1.791	1.772	EPSD	ICGC;COSMIC	1.787	Loss
AGC_RSK_RSKp90_RPS6KA1_ST	Q8IX03	WWC1	Q15418	RPS6KA1	T532	S539P	539	Missense	distal	7	no	1.791	1.894	EPSD	ICGC;COSMIC	1.787	Up-regulation
AGC_RSK_RSKp90_RPS6KA1_ST	Q8IX03	WWC1	Q15418	RPS6KA1	T532	T527I	527	Missense	distal	-5	no	1.791	1.593	EPSD	ICGC;COSMIC	1.787	Loss
AGC_RSK_RSKp90_RPS6KA1_ST	Q8IX03	WWC1	Q15418	RPS6KA1	T532	S535F	535	Missense	distal	3	no	1.791	1.850	EPSD	ICGC	1.787	Up-regulation
AGC_RSK_RSKp90_RPS6KA1_ST	Q8IX03	WWC1	Q15418	RPS6KA1	S548	S542T	542	Missense	distal	-6	no	1.096	1.793	EPSD	ICGC;COSMIC	1.787	Gain
AGC_RSK_RSKp90_RPS6KA1_ST	Q8IX03	WWC1	Q15418	RPS6KA1	S644	R640I	640	Missense	distal	-4	no	2.148	2.022	EPSD	ICGC	1.787	Down-regulation
AGC_RSK_RSKp90_RPS6KA1_ST	Q8IX03	WWC1	Q15418	RPS6KA1	S644	S637T	637	Missense	distal	-7	no	2.148	2.137	EPSD	ICGC	1.787	Down-regulation
AGC_RSK_RSKp90_RPS6KA1_ST	Q8IX03	WWC1	Q15418	RPS6KA1	S974	S975L	975	Missense	proximal	1	no	1.905	1.999	EPSD	ICGC;COSMIC	1.787	Up-regulation
AGC_RSK_RSKp90_RPS6KA1_ST	Q8IX03	WWC1	Q15418	RPS6KA1	S974	R980H	980	Missense	distal	6	no	1.905	1.926	EPSD	ICGC;COSMIC	1.787	Up-regulation
AGC_RSK_RSKp90_RPS6KA1_ST	Q8IX03	WWC1	Q15418	RPS6KA1	S974	P973L	973	Missense	proximal	-1	no	1.905	1.711	EPSD	ICGC;COSMIC	1.787	Loss
AGC_RSK_RSKp90_RPS6KA1_ST	Q8IX03	WWC1	Q15418	RPS6KA1	S974	R980C	980	Missense	distal	6	no	1.905	1.727	EPSD	ICGC;COSMIC	1.787	Loss
AGC_RSK_RSKp90_RPS6KA1_ST	Q8IX03	WWC1	Q15418	RPS6KA1	S974	S981C	981	Missense	distal	7	no	1.905	2.102	EPSD	ICGC;COSMIC	1.787	Up-regulation
AGC_RSK_RSKp90_RPS6KA1_ST	Q8IX03	WWC1	Q15418	RPS6KA1	S974	P973S	973	Missense	proximal	-1	no	1.905	1.922	EPSD	ICGC;COSMIC	1.787	Up-regulation
AGC_RSK_RSKp90_RPS6KA1_ST	Q8IX03	WWC1	Q15418	RPS6KA1	S981	S975L	975	Missense	distal	-6	no	1.697	2.196	EPSD	ICGC;COSMIC	1.787	Gain
AGC_RSK_RSKp90_RPS6KA1_ST	Q8IX03	WWC1	Q15418	RPS6KA1	S981	R983C	983	Missense	proximal	2	no	1.697	1.806	EPSD	ICGC;COSMIC	1.787	Gain
AGC_RSK_RSKp90_RPS6KA1_ST	Q8IX03	WWC1	Q15418	RPS6KA1	S981	R980H	980	Missense	proximal	-1	no	1.697	1.843	EPSD	ICGC;COSMIC	1.787	Gain
AGC_RSK_RSKp90_RPS6KA1_ST	Q8IX03	WWC1	Q15418	RPS6KA1	S981	R980C	980	Missense	proximal	-1	no	1.697	1.960	EPSD	ICGC;COSMIC	1.787	Gain
AGC_RSK_RSKp90_RPS6KA1_ST	Q8IX03	WWC1	Q15418	RPS6KA1	T1006	W1001L	1001	Missense	distal	-5	no	2.170	2.191	EPSD	ICGC	1.787	Up-regulation
AGC_RSK_RSKp90_RPS6KA1_ST	Q8IX03	WWC1	Q15418	RPS6KA1	T1006	E1008K	1008	Missense	proximal	2	no	2.170	2.040	EPSD	ICGC;COSMIC	1.787	Down-regulation
AGC_RSK_RSKp90_RPS6KA1_ST	Q8N122	RPTOR	Q15418	RPS6KA1	T126	D128Y	128	Missense	proximal	2	no	2.082	2.106	EPSD	ICGC;COSMIC	1.787	Up-regulation
AGC_RSK_RSKp90_RPS6KA1_ST	Q8N122	RPTOR	Q15418	RPS6KA1	T126	P125T	125	Missense	proximal	-1	no	2.082	2.037	EPSD	ICGC;COSMIC	1.787	Down-regulation
AGC_RSK_RSKp90_RPS6KA1_ST	Q8N122	RPTOR	Q15418	RPS6KA1	S696	T699M	699	Missense	distal	3	no	2.534	2.428	EPSD	ICGC;COSMIC	1.787	Down-regulation
AGC_RSK_RSKp90_RPS6KA1_ST	Q8N122	RPTOR	Q15418	RPS6KA1	S854	T853M	853	Missense	proximal	-1	no	2.647	2.622	EPSD	ICGC;COSMIC	1.787	Down-regulation
AGC_RSK_RSKp90_RPS6KA1_ST	P16220	CREB1	Q15418	RPS6KA1	S133	D140A	140	Missense	distal	7	no	5.441	5.316	PhosphoSitePlus	ICGC;COSMIC	1.787	Down-regulation
AGC_RSK_RSKp90_RPS6KA1_ST	Q2M1Z3	ARHGAP31	Q15418	RPS6KA1	S272	R265L	265	Missense	distal	-7	no	1.805	1.762	EPSD	ICGC	1.787	Loss
AGC_RSK_RSKp90_RPS6KA1_ST	Q2M1Z3	ARHGAP31	Q15418	RPS6KA1	S272	N271K	271	Missense	proximal	-1	no	1.805	1.801	EPSD	ICGC;COSMIC	1.787	Down-regulation
AGC_RSK_RSKp90_RPS6KA1_ST	Q2M1Z3	ARHGAP31	Q15418	RPS6KA1	S272	S272R	272	Missense	central	0	yes	1.805	0.000	EPSD	ICGC;COSMIC	1.787	Loss
AGC_RSK_RSKp90_RPS6KA1_ST	Q2M1Z3	ARHGAP31	Q15418	RPS6KA1	S272	V277D	277	Missense	distal	5	no	1.805	1.609	EPSD	ICGC;COSMIC	1.787	Loss
AGC_RSK_RSKp90_RPS6KA1_ST	Q2M1Z3	ARHGAP31	Q15418	RPS6KA1	S382	G386S	386	Missense	distal	4	no	2.612	2.574	EPSD	ICGC;COSMIC	1.787	Down-regulation
AGC_RSK_RSKp90_RPS6KA1_ST	Q2M1Z3	ARHGAP31	Q15418	RPS6KA1	S382	H381N	381	Missense	proximal	-1	no	2.612	2.670	EPSD	ICGC;COSMIC	1.787	Up-regulation
AGC_RSK_RSKp90_RPS6KA1_ST	Q2M1Z3	ARHGAP31	Q15418	RPS6KA1	S593	P590Q	590	Missense	distal	-3	no	2.003	2.095	EPSD	ICGC;COSMIC	1.787	Up-regulation
AGC_RSK_RSKp90_RPS6KA1_ST	Q2M1Z3	ARHGAP31	Q15418	RPS6KA1	S629	P630T	630	Missense	proximal	1	no	2.075	2.103	EPSD	ICGC	1.787	Up-regulation
AGC_RSK_RSKp90_RPS6KA1_ST	Q2M1Z3	ARHGAP31	Q15418	RPS6KA1	S629	A632T	632	Missense	distal	3	no	2.075	2.154	EPSD	ICGC;COSMIC	1.787	Up-regulation
AGC_RSK_RSKp90_RPS6KA1_ST	Q2M1Z3	ARHGAP31	Q15418	RPS6KA1	S629	S623P	623	Missense	distal	-6	no	2.075	2.415	EPSD	ICGC	1.787	Up-regulation
AGC_RSK_RSKp90_RPS6KA1_ST	Q2M1Z3	ARHGAP31	Q15418	RPS6KA1	S680	T679A	679	Missense	proximal	-1	no	1.981	1.796	EPSD	ICGC;COSMIC	1.787	Down-regulation
AGC_RSK_RSKp90_RPS6KA1_ST	Q2M1Z3	ARHGAP31	Q15418	RPS6KA1	S696	I694F	694	Missense	proximal	-2	no	1.894	1.901	EPSD	ICGC	1.787	Up-regulation
AGC_RSK_RSKp90_RPS6KA1_ST	Q2M1Z3	ARHGAP31	Q15418	RPS6KA1	S696	G700W	700	Missense	distal	4	no	1.894	1.869	EPSD	ICGC;COSMIC	1.787	Down-regulation
AGC_RSK_RSKp90_RPS6KA1_ST	Q2M1Z3	ARHGAP31	Q15418	RPS6KA1	S957	R950C	950	Missense	distal	-7	no	1.879	1.799	EPSD	ICGC;COSMIC	1.787	Down-regulation
AGC_RSK_RSKp90_RPS6KA1_ST	Q2M1Z3	ARHGAP31	Q15418	RPS6KA1	S957	R950L	950	Missense	distal	-7	no	1.879	1.836	EPSD	ICGC	1.787	Down-regulation
AGC_RSK_RSKp90_RPS6KA1_ST	Q2M1Z3	ARHGAP31	Q15418	RPS6KA1	S957	D956N	956	Missense	proximal	-1	no	1.879	1.890	EPSD	ICGC;COSMIC	1.787	Up-regulation
AGC_RSK_RSKp90_RPS6KA1_ST	Q2M1Z3	ARHGAP31	Q15418	RPS6KA1	S957	P959L	959	Missense	proximal	2	no	1.879	1.696	EPSD	ICGC	1.787	Loss
AGC_RSK_RSKp90_RPS6KA1_ST	Q2M1Z3	ARHGAP31	Q15418	RPS6KA1	S972	S974N	974	Missense	proximal	2	no	2.080	1.957	EPSD	ICGC;COSMIC	1.787	Down-regulation
AGC_RSK_RSKp90_RPS6KA1_ST	Q2M1Z3	ARHGAP31	Q15418	RPS6KA1	S1036	A1041E	1041	Missense	distal	5	no	1.987	1.950	EPSD	ICGC;COSMIC	1.787	Down-regulation
AGC_RSK_RSKp90_RPS6KA1_ST	Q2M1Z3	ARHGAP31	Q15418	RPS6KA1	S1054	G1061C	1061	Missense	distal	7	no	3.090	3.120	EPSD	ICGC	1.787	Up-regulation
AGC_RSK_RSKp90_RPS6KA1_ST	Q2M1Z3	ARHGAP31	Q15418	RPS6KA1	S1054	G1060V	1060	Missense	distal	6	no	3.090	2.931	EPSD	ICGC	1.787	Down-regulation
AGC_RSK_RSKp90_RPS6KA1_ST	Q2M1Z3	ARHGAP31	Q15418	RPS6KA1	S1384	S1378G	1378	Missense	distal	-6	no	1.771	2.439	EPSD	ICGC;COSMIC;GDSC	1.787	Gain
AGC_RSK_RSKp90_RPS6KA1_ST	Q2M1Z3	ARHGAP31	Q15418	RPS6KA1	T1396	V1398D	1398	Missense	proximal	2	no	3.378	3.278	EPSD	ICGC	1.787	Down-regulation
AGC_RSK_RSKp90_RPS6KA1_ST	P49841	GSK3B	Q15418	RPS6KA1	T59	E53K	53	Missense	distal	-6	no	1.676	2.150	EPSD	ICGC;COSMIC	1.787	Gain
AGC_RSK_RSKp90_RPS6KA1_ST	P49841	GSK3B	Q15418	RPS6KA1	T324	R319H	319	Missense	distal	-5	no	2.230	2.318	EPSD	ICGC;COSMIC	1.787	Up-regulation
AGC_RSK_RSKp90_RPS6KA1_ST	P49841	GSK3B	Q15418	RPS6KA1	T324	A327P	327	Missense	distal	3	no	2.230	2.252	EPSD	ICGC;COSMIC	1.787	Up-regulation
AGC_RSK_RSKp90_RPS6KA1_ST	P49841	GSK3B	Q15418	RPS6KA1	T324	R328L	328	Missense	distal	4	no	2.230	2.278	EPSD	ICGC;COSMIC	1.787	Up-regulation
AGC_RSK_RSKp90_RPS6KA1_ST	P49841	GSK3B	Q15418	RPS6KA1	T324	P331L	331	Missense	distal	7	no	2.230	2.135	EPSD	ICGC;COSMIC	1.787	Down-regulation
AGC_RSK_RSKp90_RPS6KA1_ST	P49841	GSK3B	Q15418	RPS6KA1	T324	R328Q	328	Missense	distal	4	no	2.230	2.235	EPSD	ICGC	1.787	Up-regulation
AGC_RSK_RSKp90_RPS6KA1_ST	P49841	GSK3B	Q15418	RPS6KA1	T324	L321M	321	Missense	distal	-3	no	2.230	1.933	EPSD	ICGC;COSMIC	1.787	Down-regulation
AGC_RSK_RSKp90_RPS6KA1_ST	P49841	GSK3B	Q15418	RPS6KA1	T390	S389P	389	Missense	proximal	-1	no	1.859	1.842	EPSD	ICGC;COSMIC	1.787	Down-regulation
AGC_RSK_RSKp90_RPS6KA1_ST	P49841	GSK3B	Q15418	RPS6KA1	T390	A397T	397	Missense	distal	7	no	1.859	1.863	EPSD	ICGC;COSMIC	1.787	Up-regulation
AGC_RSK_RSKp90_RPS6KA1_ST	P49841	GSK3B	Q15418	RPS6KA1	T390	R383Q	383	Missense	distal	-7	no	1.859	1.808	EPSD	ICGC;COSMIC	1.787	Down-regulation
AGC_RSK_RSKp90_RPS6KA1_ST	P30305	CDC25B	Q15418	RPS6KA1	S67	S67R	67	Missense	central	0	yes	2.025	0.000	EPSD	ICGC	1.787	Loss
AGC_RSK_RSKp90_RPS6KA1_ST	P30305	CDC25B	Q15418	RPS6KA1	S91	T86M	86	Missense	distal	-5	no	2.641	2.481	EPSD	ICGC;COSMIC	1.787	Down-regulation
AGC_RSK_RSKp90_RPS6KA1_ST	P30305	CDC25B	Q15418	RPS6KA1	S229	S229R	229	Missense	central	0	yes	3.059	0.000	EPSD	ICGC;COSMIC	1.787	Loss
AGC_RSK_RSKp90_RPS6KA1_ST	P30305	CDC25B	Q15418	RPS6KA1	S229	S230T	230	Missense	proximal	1	no	3.059	3.133	EPSD	ICGC;COSMIC	1.787	Up-regulation
AGC_RSK_RSKp90_RPS6KA1_ST	P30305	CDC25B	Q15418	RPS6KA1	S229	P232T	232	Missense	distal	3	no	3.059	3.115	EPSD	ICGC;COSMIC	1.787	Up-regulation
AGC_RSK_RSKp90_RPS6KA1_ST	P30305	CDC25B	Q15418	RPS6KA1	S313	V310I	310	Missense	distal	-3	no	2.414	2.859	EPSD	ICGC;COSMIC	1.787	Up-regulation
AGC_RSK_RSKp90_RPS6KA1_ST	P30305	CDC25B	Q15418	RPS6KA1	S313	R320C	320	Missense	distal	7	no	2.414	2.503	EPSD	ICGC	1.787	Up-regulation
AGC_RSK_RSKp90_RPS6KA1_ST	P30307	CDC25C	Q15418	RPS6KA1	S38	L33P	33	Missense	distal	-5	no	3.201	3.197	EPSD	ICGC;COSMIC	1.787	Down-regulation
AGC_RSK_RSKp90_RPS6KA1_ST	P30307	CDC25C	Q15418	RPS6KA1	S216	E219D	219	Missense	distal	3	no	2.845	2.853	EPSD	ICGC;COSMIC	1.787	Up-regulation
AGC_RSK_RSKp90_RPS6KA1_ST	P49815	TSC2	Q15418	RPS6KA1	S311	S315L	315	Missense	distal	4	no	1.873	1.924	EPSD	ICGC;COSMIC	1.787	Up-regulation
AGC_RSK_RSKp90_RPS6KA1_ST	P49815	TSC2	Q15418	RPS6KA1	S311	R308L	308	Missense	distal	-3	no	1.873	1.957	EPSD	ICGC;COSMIC	1.787	Up-regulation
AGC_RSK_RSKp90_RPS6KA1_ST	P49815	TSC2	Q15418	RPS6KA1	S311	A306D	306	Missense	distal	-5	no	1.873	2.088	EPSD	ICGC;COSMIC	1.787	Up-regulation
AGC_RSK_RSKp90_RPS6KA1_ST	P49815	TSC2	Q15418	RPS6KA1	S609	Y602H	602	Missense	distal	-7	no	1.958	1.981	EPSD	ICGC;COSMIC;GDSC;CCLE	1.787	Up-regulation
AGC_RSK_RSKp90_RPS6KA1_ST	P49815	TSC2	Q15418	RPS6KA1	S609	A607T	607	Missense	proximal	-2	no	1.958	2.025	EPSD	ICGC;COSMIC;GDSC	1.787	Up-regulation
AGC_RSK_RSKp90_RPS6KA1_ST	P49815	TSC2	Q15418	RPS6KA1	T927	E929K	929	Missense	proximal	2	no	1.808	1.678	EPSD	ICGC	1.787	Loss
AGC_RSK_RSKp90_RPS6KA1_ST	P49815	TSC2	Q15418	RPS6KA1	T927	R934M	934	Missense	distal	7	no	1.808	1.702	EPSD	ICGC;COSMIC	1.787	Loss
AGC_RSK_RSKp90_RPS6KA1_ST	P49815	TSC2	Q15418	RPS6KA1	S979	E973K	973	Missense	distal	-6	no	1.433	1.908	EPSD	ICGC;COSMIC	1.787	Gain
AGC_RSK_RSKp90_RPS6KA1_ST	P49815	TSC2	Q15418	RPS6KA1	S981	R976G	976	Missense	distal	-5	no	1.618	1.822	EPSD	ICGC	1.787	Gain
AGC_RSK_RSKp90_RPS6KA1_ST	P49815	TSC2	Q15418	RPS6KA1	S999	S1002F	1002	Missense	distal	3	no	1.893	1.952	EPSD	ICGC;COSMIC	1.787	Up-regulation
AGC_RSK_RSKp90_RPS6KA1_ST	P49815	TSC2	Q15418	RPS6KA1	S999	S1002Y	1002	Missense	distal	3	no	1.893	1.905	EPSD	ICGC;COSMIC	1.787	Up-regulation
AGC_RSK_RSKp90_RPS6KA1_ST	P49815	TSC2	Q15418	RPS6KA1	S1337	S1336L	1336	Missense	proximal	-1	no	2.255	2.044	EPSD	ICGC;COSMIC	1.787	Down-regulation
AGC_RSK_RSKp90_RPS6KA1_ST	O00418	EEF2K	Q15418	RPS6KA1	S18	H23R	23	Missense	distal	5	no	1.602	1.949	EPSD	ICGC;COSMIC	1.787	Gain
AGC_RSK_RSKp90_RPS6KA1_ST	O00418	EEF2K	Q15418	RPS6KA1	S71	P75A	75	Missense	distal	4	no	1.969	1.955	EPSD	ICGC;COSMIC	1.787	Down-regulation
AGC_RSK_RSKp90_RPS6KA1_ST	O00418	EEF2K	Q15418	RPS6KA1	S71	P75L	75	Missense	distal	4	no	1.969	1.993	EPSD	ICGC;COSMIC	1.787	Up-regulation
AGC_RSK_RSKp90_RPS6KA1_ST	O00418	EEF2K	Q15418	RPS6KA1	S71	S71F	71	Missense	central	0	yes	1.969	0.000	EPSD	ICGC;COSMIC	1.787	Loss
AGC_RSK_RSKp90_RPS6KA1_ST	O00418	EEF2K	Q15418	RPS6KA1	S71	S66R	66	Missense	distal	-5	no	1.969	1.944	EPSD	ICGC	1.787	Down-regulation
AGC_RSK_RSKp90_RPS6KA1_ST	O00418	EEF2K	Q15418	RPS6KA1	S241	R247H	247	Missense	distal	6	no	1.778	1.799	EPSD	ICGC;COSMIC	1.787	Gain
AGC_RSK_RSKp90_RPS6KA1_ST	O00418	EEF2K	Q15418	RPS6KA1	S241	D248N	248	Missense	distal	7	no	1.778	1.790	EPSD	ICGC	1.787	Gain
AGC_RSK_RSKp90_RPS6KA1_ST	O00418	EEF2K	Q15418	RPS6KA1	S241	Y236C	236	Missense	distal	-5	no	1.778	1.923	EPSD	ICGC;COSMIC	1.787	Gain
AGC_RSK_RSKp90_RPS6KA1_ST	O00418	EEF2K	Q15418	RPS6KA1	S241	S243Y	243	Missense	proximal	2	no	1.778	1.817	EPSD	ICGC;COSMIC	1.787	Gain
AGC_RSK_RSKp90_RPS6KA1_ST	O00418	EEF2K	Q15418	RPS6KA1	T340	K347N	347	Missense	distal	7	no	1.985	2.116	EPSD	ICGC;COSMIC	1.787	Up-regulation
AGC_RSK_RSKp90_RPS6KA1_ST	O00418	EEF2K	Q15418	RPS6KA1	S359	Q361R	361	Missense	proximal	2	no	2.297	2.531	EPSD	ICGC	1.787	Up-regulation
AGC_RSK_RSKp90_RPS6KA1_ST	O00418	EEF2K	Q15418	RPS6KA1	S359	P360L	360	Missense	proximal	1	no	2.297	2.345	EPSD	ICGC	1.787	Up-regulation
AGC_RSK_RSKp90_RPS6KA1_ST	O00418	EEF2K	Q15418	RPS6KA1	T364	R369W	369	Missense	distal	5	no	2.078	1.892	EPSD	ICGC	1.787	Down-regulation
AGC_RSK_RSKp90_RPS6KA1_ST	O00418	EEF2K	Q15418	RPS6KA1	T364	Q361R	361	Missense	distal	-3	no	2.078	2.488	EPSD	ICGC	1.787	Up-regulation
AGC_RSK_RSKp90_RPS6KA1_ST	O00418	EEF2K	Q15418	RPS6KA1	T364	P360L	360	Missense	distal	-4	no	2.078	2.147	EPSD	ICGC	1.787	Up-regulation
AGC_RSK_RSKp90_RPS6KA1_ST	O00418	EEF2K	Q15418	RPS6KA1	S478	D471Y	471	Missense	distal	-7	no	1.938	1.903	EPSD	ICGC	1.787	Down-regulation
AGC_RSK_RSKp90_RPS6KA1_ST	P03372	ESR1	Q15418	RPS6KA1	S46	V51M	51	Missense	distal	5	no	1.897	1.787	EPSD	ICGC	1.787	Down-regulation
AGC_RSK_RSKp90_RPS6KA1_ST	P03372	ESR1	Q15418	RPS6KA1	S46	D45E	45	Missense	proximal	-1	no	1.897	1.850	EPSD	ICGC;COSMIC	1.787	Down-regulation
AGC_RSK_RSKp90_RPS6KA1_ST	P03372	ESR1	Q15418	RPS6KA1	S46	A50S	50	Missense	distal	4	no	1.897	1.885	EPSD	ICGC	1.787	Down-regulation
AGC_RSK_RSKp90_RPS6KA1_ST	P03372	ESR1	Q15418	RPS6KA1	S47	V51M	51	Missense	distal	4	no	2.612	2.657	EPSD	ICGC	1.787	Up-regulation
AGC_RSK_RSKp90_RPS6KA1_ST	P03372	ESR1	Q15418	RPS6KA1	S47	D45E	45	Missense	proximal	-2	no	2.612	2.587	EPSD	ICGC;COSMIC	1.787	Down-regulation
AGC_RSK_RSKp90_RPS6KA1_ST	P03372	ESR1	Q15418	RPS6KA1	S47	A50S	50	Missense	distal	3	no	2.612	2.570	EPSD	ICGC	1.787	Down-regulation
AGC_RSK_RSKp90_RPS6KA1_ST	P03372	ESR1	Q15418	RPS6KA1	S329	E330A	330	Missense	proximal	1	no	2.028	2.100	EPSD	ICGC	1.787	Up-regulation
AGC_RSK_RSKp90_RPS6KA1_ST	P03372	ESR1	Q15418	RPS6KA1	S329	P324T	324	Missense	distal	-5	no	2.028	2.093	EPSD	ICGC	1.787	Up-regulation
AGC_RSK_RSKp90_RPS6KA1_ST	P03372	ESR1	Q15418	RPS6KA1	S329	A322S	322	Missense	distal	-7	no	2.028	2.033	EPSD	ICGC	1.787	Up-regulation
AGC_RSK_RSKp90_RPS6KA1_ST	P03372	ESR1	Q15418	RPS6KA1	S329	E330K	330	Missense	proximal	1	no	2.028	2.071	EPSD	ICGC;COSMIC	1.787	Up-regulation
AGC_RSK_RSKp90_RPS6KA1_ST	P03372	ESR1	Q15418	RPS6KA1	S329	P336A	336	Missense	distal	7	no	2.028	1.878	EPSD	ICGC;COSMIC	1.787	Down-regulation
AGC_RSK_RSKp90_RPS6KA1_ST	P03372	ESR1	Q15418	RPS6KA1	T485	V478L	478	Missense	distal	-7	no	1.859	1.881	EPSD	ICGC;COSMIC	1.787	Up-regulation
AGC_RSK_RSKp90_RPS6KA1_ST	O14745	SLC9A3R1	Q15418	RPS6KA1	T156	R151L	151	Missense	distal	-5	no	1.780	1.943	PhosphoSitePlus	ICGC	1.787	Gain
AGC_RSK_RSKp90_RPS6KA1_ST	P62753	RPS6	Q15418	RPS6KA1	S82	G80W	80	Missense	proximal	-2	no	2.557	2.496	EPSD	ICGC;COSMIC	1.787	Down-regulation
AGC_RSK_RSKp90_RPS6KA1_ST	P62753	RPS6	Q15418	RPS6KA1	S107	L106M	106	Missense	proximal	-1	no	2.242	2.368	EPSD	ICGC;COSMIC	1.787	Up-regulation
AGC_RSK_RSKp90_RPS6KA1_ST	O75030	MITF	Q15418	RPS6KA1	S409	L404F	404	Missense	distal	-5	no	2.392	2.379	PhosphoSitePlus	ICGC	1.787	Down-regulation
AGC_RSK_RSKp90_RPS6KA1_ST	O75030	MITF	Q15418	RPS6KA1	S409	D416N	416	Missense	distal	7	no	2.392	2.404	PhosphoSitePlus	ICGC	1.787	Up-regulation
AGC_RSK_RSKp90_RPS6KA1_ST	O75030	MITF	Q15418	RPS6KA1	S409	L404P	404	Missense	distal	-5	no	2.392	2.387	PhosphoSitePlus	ICGC;COSMIC	1.787	Down-regulation
AGC_RSK_RSKp90_RPS6KA1_ST	O75030	MITF	Q15418	RPS6KA1	T410	L404F	404	Missense	distal	-6	no	2.101	1.731	EPSD	ICGC	1.787	Loss
AGC_RSK_RSKp90_RPS6KA1_ST	O75030	MITF	Q15418	RPS6KA1	T410	D416N	416	Missense	distal	6	no	2.101	2.212	EPSD	ICGC	1.787	Up-regulation
AGC_RSK_RSKp90_RPS6KA1_ST	O75030	MITF	Q15418	RPS6KA1	T410	L404P	404	Missense	distal	-6	no	2.101	1.942	EPSD	ICGC;COSMIC	1.787	Down-regulation
AGC_RSK_RSKp90_RPS6KA1_ST	O75030	MITF	Q15418	RPS6KA1	T489	D483G	483	Missense	distal	-6	no	1.512	2.066	EPSD	ICGC	1.787	Gain
AGC_RSK_RSKp90_RPS6KA1_ST	O75030	MITF	Q15418	RPS6KA1	S502	G506R	506	Missense	distal	4	no	1.928	1.891	EPSD	ICGC;COSMIC	1.787	Down-regulation
AGC_RSK_RSKp90_RPS6KA1_ST	O75030	MITF	Q15418	RPS6KA1	S502	S504C	504	Missense	proximal	2	no	1.928	2.189	EPSD	ICGC;COSMIC	1.787	Up-regulation
AGC_RSK_RSKp90_RPS6KA1_ST	O75030	MITF	Q15418	RPS6KA1	S502	T496N	496	Missense	distal	-6	no	1.928	1.335	EPSD	ICGC;COSMIC	1.787	Loss
AGC_RSK_RSKp90_RPS6KA1_ST	O75030	MITF	Q15418	RPS6KA1	S502	S504P	504	Missense	proximal	2	no	1.928	2.106	EPSD	ICGC	1.787	Up-regulation
AGC_RSK_RSKp90_RPS6KA1_ST	O75030	MITF	Q15418	RPS6KA1	S502	D497G	497	Missense	distal	-5	no	1.928	1.871	EPSD	ICGC;COSMIC	1.787	Down-regulation
AGC_RSK_RSKp90_RPS6KA1_ST	O75030	MITF	Q15418	RPS6KA1	S502	L500F	500	Missense	proximal	-2	no	1.928	1.935	EPSD	ICGC;COSMIC	1.787	Up-regulation
AGC_RSK_RSKp90_RPS6KA1_ST	P21333	FLNA	Q15418	RPS6KA1	S72	R76W	76	Missense	distal	4	no	2.202	2.213	EPSD	ICGC;COSMIC	1.787	Up-regulation
AGC_RSK_RSKp90_RPS6KA1_ST	P21333	FLNA	Q15418	RPS6KA1	S72	G74R	74	Missense	proximal	2	no	2.202	2.197	EPSD	ICGC;COSMIC	1.787	Down-regulation
AGC_RSK_RSKp90_RPS6KA1_ST	P21333	FLNA	Q15418	RPS6KA1	S72	S72R	72	Missense	central	0	yes	2.202	0.000	EPSD	ICGC;COSMIC	1.787	Loss
AGC_RSK_RSKp90_RPS6KA1_ST	P21333	FLNA	Q15418	RPS6KA1	S72	D73Y	73	Missense	proximal	1	no	2.202	2.258	EPSD	ICGC;COSMIC	1.787	Up-regulation
AGC_RSK_RSKp90_RPS6KA1_ST	P21333	FLNA	Q15418	RPS6KA1	S481	R484L	484	Missense	distal	3	no	1.649	1.822	EPSD	ICGC;COSMIC	1.787	Gain
AGC_RSK_RSKp90_RPS6KA1_ST	P21333	FLNA	Q15418	RPS6KA1	T685	E683K	683	Missense	proximal	-2	no	1.908	1.942	EPSD	ICGC	1.787	Up-regulation
AGC_RSK_RSKp90_RPS6KA1_ST	P21333	FLNA	Q15418	RPS6KA1	T950	P955H	955	Missense	distal	5	no	1.969	1.826	EPSD	ICGC;COSMIC	1.787	Down-regulation
AGC_RSK_RSKp90_RPS6KA1_ST	P21333	FLNA	Q15418	RPS6KA1	T950	G953V	953	Missense	distal	3	no	1.969	1.962	EPSD	ICGC;COSMIC	1.787	Down-regulation
AGC_RSK_RSKp90_RPS6KA1_ST	P21333	FLNA	Q15418	RPS6KA1	T1427	G1430S	1430	Missense	distal	3	no	2.803	2.751	EPSD	ICGC;COSMIC	1.787	Down-regulation
AGC_RSK_RSKp90_RPS6KA1_ST	P21333	FLNA	Q15418	RPS6KA1	T1558	P1565T	1565	Missense	distal	7	no	2.077	1.932	EPSD	ICGC	1.787	Down-regulation
AGC_RSK_RSKp90_RPS6KA1_ST	P21333	FLNA	Q15418	RPS6KA1	S1630	G1623V	1623	Missense	distal	-7	no	1.891	1.900	EPSD	ICGC;COSMIC	1.787	Up-regulation
AGC_RSK_RSKp90_RPS6KA1_ST	P21333	FLNA	Q15418	RPS6KA1	S1630	R1633S	1633	Missense	distal	3	no	1.891	1.935	EPSD	ICGC	1.787	Up-regulation
AGC_RSK_RSKp90_RPS6KA1_ST	P21333	FLNA	Q15418	RPS6KA1	S1991	T1984M	1984	Missense	distal	-7	no	2.402	2.413	EPSD	ICGC;COSMIC	1.787	Up-regulation
AGC_RSK_RSKp90_RPS6KA1_ST	P21333	FLNA	Q15418	RPS6KA1	S1991	R1993Q	1993	Missense	proximal	2	no	2.402	2.167	EPSD	ICGC;COSMIC	1.787	Down-regulation
AGC_RSK_RSKp90_RPS6KA1_ST	P21333	FLNA	Q15418	RPS6KA1	S2260	A2266V	2266	Missense	distal	6	no	2.156	2.082	EPSD	ICGC	1.787	Down-regulation
AGC_RSK_RSKp90_RPS6KA1_ST	P21333	FLNA	Q15418	RPS6KA1	S2414	P2415L	2415	Missense	proximal	1	no	2.574	2.622	EPSD	ICGC	1.787	Up-regulation
AGC_RSK_RSKp90_RPS6KA1_ST	P78371	CCT2	Q15418	RPS6KA1	S28	A32S	32	Missense	distal	4	no	2.187	2.175	EPSD	ICGC	1.787	Down-regulation
AGC_RSK_RSKp90_RPS6KA1_ST	P78371	CCT2	Q15418	RPS6KA1	S28	A24S	24	Missense	distal	-4	no	2.187	2.080	EPSD	ICGC;COSMIC	1.787	Down-regulation
AGC_RSK_RSKp90_RPS6KA1_ST	P78371	CCT2	Q15418	RPS6KA1	S28	A24D	24	Missense	distal	-4	no	2.187	2.048	EPSD	ICGC;COSMIC	1.787	Down-regulation
AGC_RSK_RSKp90_RPS6KA1_ST	P78371	CCT2	Q15418	RPS6KA1	S60	D66H	66	Missense	distal	6	no	2.289	2.330	EPSD	ICGC;COSMIC	1.787	Up-regulation
AGC_RSK_RSKp90_RPS6KA1_ST	P78371	CCT2	Q15418	RPS6KA1	S60	R57L	57	Missense	distal	-3	no	2.289	2.372	EPSD	ICGC	1.787	Up-regulation
AGC_RSK_RSKp90_RPS6KA1_ST	P78371	CCT2	Q15418	RPS6KA1	S60	D58Y	58	Missense	proximal	-2	no	2.289	2.284	EPSD	ICGC;COSMIC	1.787	Down-regulation
AGC_RSK_RSKp90_RPS6KA1_ST	P78371	CCT2	Q15418	RPS6KA1	S60	V63I	63	Missense	distal	3	no	2.289	2.302	EPSD	ICGC;COSMIC	1.787	Up-regulation
AGC_RSK_RSKp90_RPS6KA1_ST	P78371	CCT2	Q15418	RPS6KA1	T406	G411V	411	Missense	distal	5	no	1.580	1.943	EPSD	ICGC	1.787	Gain
AGC_RSK_RSKp90_RPS6KA1_ST	Q53EL6	PDCD4	Q15418	RPS6KA1	S48	A47S	47	Missense	proximal	-1	no	1.659	1.905	EPSD	ICGC	1.787	Gain
AGC_RSK_RSKp90_RPS6KA1_ST	Q53EL6	PDCD4	Q15418	RPS6KA1	S71	S76L	76	Missense	distal	5	no	1.924	1.914	EPSD	ICGC;COSMIC	1.787	Down-regulation
AGC_RSK_RSKp90_RPS6KA1_ST	Q53EL6	PDCD4	Q15418	RPS6KA1	S71	R69L	69	Missense	proximal	-2	no	1.924	1.993	EPSD	ICGC	1.787	Up-regulation
AGC_RSK_RSKp90_RPS6KA1_ST	Q53EL6	PDCD4	Q15418	RPS6KA1	S71	G72V	72	Missense	proximal	1	no	1.924	1.993	EPSD	ICGC	1.787	Up-regulation
AGC_RSK_RSKp90_RPS6KA1_ST	Q53EL6	PDCD4	Q15418	RPS6KA1	S94	G88E	88	Missense	distal	-6	no	3.119	2.631	EPSD	ICGC	1.787	Down-regulation
AGC_RSK_RSKp90_RPS6KA1_ST	Q53EL6	PDCD4	Q15418	RPS6KA1	T234	C227F	227	Missense	distal	-7	no	1.853	1.889	EPSD	ICGC	1.787	Up-regulation
AGC_RSK_RSKp90_RPS6KA1_ST	Q53EL6	PDCD4	Q15418	RPS6KA1	S313	W315C	315	Missense	proximal	2	no	2.077	2.246	EPSD	ICGC;COSMIC	1.787	Up-regulation
AGC_RSK_RSKp90_RPS6KA1_ST	Q53EL6	PDCD4	Q15418	RPS6KA1	S313	G318V	318	Missense	distal	5	no	2.077	2.440	EPSD	ICGC;COSMIC	1.787	Up-regulation
AGC_RSK_RSKp90_RPS6KA1_ST	Q53EL6	PDCD4	Q15418	RPS6KA1	S393	S393C	393	Missense	central	0	yes	1.799	0.000	EPSD	ICGC;COSMIC	1.787	Loss
AGC_RSK_RSKp90_RPS6KA1_ST	Q07889	SOS1	Q15418	RPS6KA1	S403	R406Q	406	Missense	distal	3	no	2.640	2.704	EPSD	ICGC;COSMIC	1.787	Up-regulation
AGC_RSK_RSKp90_RPS6KA1_ST	Q07889	SOS1	Q15418	RPS6KA1	S1134	V1135I	1135	Missense	proximal	1	no	2.053	2.173	PhosphoSitePlus;EPSD	ICGC;COSMIC	1.787	Up-regulation
AGC_RSK_RSKp90_RPS6KA1_ST	Q07889	SOS1	Q15418	RPS6KA1	S1134	P1130Q	1130	Missense	distal	-4	no	2.053	1.903	PhosphoSitePlus;EPSD	ICGC	1.787	Down-regulation
AGC_RSK_RSKp90_RPS6KA1_ST	Q07889	SOS1	Q15418	RPS6KA1	S1139	V1135I	1135	Missense	distal	-4	no	2.117	2.212	EPSD	ICGC;COSMIC	1.787	Up-regulation
AGC_RSK_RSKp90_RPS6KA1_ST	Q07889	SOS1	Q15418	RPS6KA1	T1141	V1135I	1135	Missense	distal	-6	no	1.546	1.994	EPSD	ICGC;COSMIC	1.787	Gain
AGC_RSK_RSKp90_RPS6KA1_ST	Q07889	SOS1	Q15418	RPS6KA1	S1166	I1171S	1171	Missense	distal	5	no	1.813	1.755	EPSD	ICGC	1.787	Loss
AGC_RSK_RSKp90_RPS6KA1_ST	Q07889	SOS1	Q15418	RPS6KA1	S1166	P1168T	1168	Missense	proximal	2	no	1.813	1.732	EPSD	ICGC	1.787	Loss
AGC_RSK_RSKp90_RPS6KA1_ST	Q07889	SOS1	Q15418	RPS6KA1	S1166	P1168R	1168	Missense	proximal	2	no	1.813	1.786	EPSD	ICGC;COSMIC	1.787	Loss
AGC_RSK_RSKp90_RPS6KA1_ST	O14727	APAF1	Q15418	RPS6KA1	S238	L239F	239	Missense	proximal	1	no	1.795	1.763	EPSD	ICGC	1.787	Loss
AGC_RSK_RSKp90_RPS6KA1_ST	O14727	APAF1	Q15418	RPS6KA1	S238	L242F	242	Missense	distal	4	no	1.795	1.772	EPSD	ICGC;COSMIC	1.787	Loss
AGC_RSK_RSKp90_RPS6KA1_ST	O14727	APAF1	Q15418	RPS6KA1	S268	K267N	267	Missense	proximal	-1	no	2.874	2.878	EPSD;PhosphoSitePlus	ICGC	1.787	Up-regulation
AGC_RSK_RSKp90_RPS6KA1_ST	O14727	APAF1	Q15418	RPS6KA1	S432	R434C	434	Missense	proximal	2	no	2.396	2.506	EPSD	ICGC;COSMIC	1.787	Up-regulation
AGC_RSK_RSKp90_RPS6KA1_ST	O14727	APAF1	Q15418	RPS6KA1	S432	S432L	432	Missense	central	0	yes	2.396	0.000	EPSD	ICGC	1.787	Loss
AGC_RSK_RSKp90_RPS6KA1_ST	P53355	DAPK1	Q15418	RPS6KA1	S326	S321L	321	Missense	distal	-5	no	2.159	2.298	EPSD	ICGC;COSMIC	1.787	Up-regulation
AGC_RSK_RSKp90_RPS6KA1_ST	P53355	DAPK1	Q15418	RPS6KA1	S326	S333R	333	Missense	distal	7	no	2.159	2.267	EPSD	ICGC	1.787	Up-regulation
AGC_RSK_RSKp90_RPS6KA1_ST	P53355	DAPK1	Q15418	RPS6KA1	S696	F693I	693	Missense	distal	-3	no	1.724	1.995	EPSD	ICGC;COSMIC	1.787	Gain
AGC_RSK_RSKp90_RPS6KA1_ST	P53355	DAPK1	Q15418	RPS6KA1	S1115	R1114C	1114	Missense	proximal	-1	no	2.472	2.734	EPSD	ICGC;COSMIC	1.787	Up-regulation
AGC_RSK_RSKp90_RPS6KA1_ST	P53355	DAPK1	Q15418	RPS6KA1	S1115	D1110N	1110	Missense	distal	-5	no	2.472	2.495	EPSD	ICGC;COSMIC	1.787	Up-regulation
AGC_RSK_RSKp90_RPS6KA1_ST	P53355	DAPK1	Q15418	RPS6KA1	S1115	E1122K	1122	Missense	distal	7	no	2.472	2.402	EPSD	ICGC;COSMIC	1.787	Down-regulation
AGC_RSK_RSKp90_RPS6KA1_ST	P53355	DAPK1	Q15418	RPS6KA1	S1115	A1117D	1117	Missense	proximal	2	no	2.472	2.680	EPSD	ICGC;COSMIC	1.787	Up-regulation
AGC_RSK_RSKp90_RPS6KA1_ST	P53355	DAPK1	Q15418	RPS6KA1	S1115	W1116C	1116	Missense	proximal	1	no	2.472	2.411	EPSD	ICGC;COSMIC	1.787	Down-regulation
AGC_RSK_RSKp90_RPS6KA1_ST	P53355	DAPK1	Q15418	RPS6KA1	S1115	A1117T	1117	Missense	proximal	2	no	2.472	2.763	EPSD	ICGC;COSMIC	1.787	Up-regulation
AGC_RSK_RSKp90_RPS6KA1_ST	Q9UBP6	METTL1	Q15418	RPS6KA1	S177	T179N	179	Missense	proximal	2	no	2.614	2.393	EPSD	ICGC;COSMIC	1.787	Down-regulation
AGC_RSK_RSKp90_RPS6KA1_ST	Q92882	OSTF1	Q15418	RPS6KA1	T195	R199L	199	Missense	distal	4	no	1.937	1.985	EPSD	ICGC;COSMIC	1.787	Up-regulation
AGC_RSK_RSKp90_RPS6KA1_ST	Q92882	OSTF1	Q15418	RPS6KA1	T195	L188V	188	Missense	distal	-7	no	1.937	1.914	EPSD	ICGC;COSMIC	1.787	Down-regulation
AGC_RSK_RSKp90_RPS6KA1_ST	Q92882	OSTF1	Q15418	RPS6KA1	T195	Q193H	193	Missense	proximal	-2	no	1.937	1.949	EPSD	ICGC;COSMIC	1.787	Up-regulation
AGC_RSK_RSKp90_RPS6KA1_ST	P30304	CDC25A	Q15418	RPS6KA1	S107	S107Y	107	Missense	central	0	yes	1.987	0.000	EPSD	ICGC	1.787	Loss
AGC_RSK_RSKp90_RPS6KA1_ST	P30304	CDC25A	Q15418	RPS6KA1	S279	P285H	285	Missense	distal	6	no	1.935	2.020	EPSD	ICGC;COSMIC	1.787	Up-regulation
AGC_RSK_RSKp90_RPS6KA1_ST	P30304	CDC25A	Q15418	RPS6KA1	S317	A319E	319	Missense	proximal	2	no	1.461	1.796	EPSD	ICGC;COSMIC	1.787	Gain
AGC_RSK_RSKp90_RPS6KA1_ST	P30304	CDC25A	Q15418	RPS6KA1	S320	S317Y	317	Missense	distal	-3	no	1.986	1.893	EPSD	ICGC	1.787	Down-regulation
AGC_RSK_RSKp90_RPS6KA1_ST	P30304	CDC25A	Q15418	RPS6KA1	S320	S315Y	315	Missense	distal	-5	no	1.986	2.104	EPSD	ICGC	1.787	Up-regulation
AGC_RSK_RSKp90_RPS6KA1_ST	P30304	CDC25A	Q15418	RPS6KA1	S320	A319E	319	Missense	proximal	-1	no	1.986	2.114	EPSD	ICGC;COSMIC	1.787	Up-regulation
AGC_RSK_RSKp90_RPS6KA1_ST	P30304	CDC25A	Q15418	RPS6KA1	S320	G324R	324	Missense	distal	4	no	1.986	1.950	EPSD	ICGC	1.787	Down-regulation
AGC_RSK_RSKp90_RPS6KA1_ST	P60983	GMFB	Q15418	RPS6KA1	T27	R24L	24	Missense	distal	-3	no	2.127	2.211	PhosphoSitePlus	ICGC	1.787	Up-regulation
AGC_RSK_RSKp90_RPS6KA1_ST	P60983	GMFB	Q15418	RPS6KA1	T27	R22H	22	Missense	distal	-5	no	2.127	2.215	PhosphoSitePlus	ICGC;COSMIC	1.787	Up-regulation
AGC_RSK_RSKp90_RPS6KA1_ST	P60983	GMFB	Q15418	RPS6KA1	S72	D79N	79	Missense	distal	7	no	2.492	2.505	EPSD	ICGC;COSMIC	1.787	Up-regulation
AGC_RSK_RSKp90_RPS6KA1_ST	P60983	GMFB	Q15418	RPS6KA1	S72	Q76E	76	Missense	distal	4	no	2.492	2.501	EPSD	ICGC	1.787	Up-regulation
AGC_RSK_RSKp90_RPS6KA1_ST	P60983	GMFB	Q15418	RPS6KA1	S72	P66H	66	Missense	distal	-6	no	2.492	2.714	EPSD	ICGC;COSMIC	1.787	Up-regulation
AGC_RSK_RSKp90_RPS6KA1_ST	P49427	CDC34	Q15418	RPS6KA1	T186	T186A	186	Missense	central	0	yes	2.010	0.000	EPSD	ICGC;COSMIC	1.787	Loss
AGC_RSK_RSKp90_RPS6KA1_ST	P29317	EPHA2	Q15418	RPS6KA1	S570	V574I	574	Missense	distal	4	no	2.741	2.801	EPSD	ICGC;COSMIC	1.787	Up-regulation
AGC_RSK_RSKp90_RPS6KA1_ST	P29317	EPHA2	Q15418	RPS6KA1	S570	A567V	567	Missense	distal	-3	no	2.741	2.175	EPSD	ICGC;COSMIC	1.787	Down-regulation
AGC_RSK_RSKp90_RPS6KA1_ST	P29317	EPHA2	Q15418	RPS6KA1	S570	Y575C	575	Missense	distal	5	no	2.741	2.686	EPSD	ICGC	1.787	Down-regulation
AGC_RSK_RSKp90_RPS6KA1_ST	P29317	EPHA2	Q15418	RPS6KA1	S636	G630S	630	Missense	distal	-6	no	2.293	1.625	EPSD	ICGC;COSMIC	1.787	Loss
AGC_RSK_RSKp90_RPS6KA1_ST	P29317	EPHA2	Q15418	RPS6KA1	T773	G777C	777	Missense	distal	4	no	2.288	2.266	EPSD	ICGC;COSMIC	1.787	Down-regulation
AGC_RSK_RSKp90_RPS6KA1_ST	P29317	EPHA2	Q15418	RPS6KA1	S790	A785T	785	Missense	distal	-5	no	1.825	2.003	EPSD	ICGC;GDSC;CCLE	1.787	Up-regulation
AGC_RSK_RSKp90_RPS6KA1_ST	P29317	EPHA2	Q15418	RPS6KA1	S790	P786Q	786	Missense	distal	-4	no	1.825	1.675	EPSD	ICGC;COSMIC	1.787	Loss
AGC_RSK_RSKp90_RPS6KA1_ST	P29317	EPHA2	Q15418	RPS6KA1	S869	I870M	870	Missense	proximal	1	no	3.076	3.016	EPSD	ICGC;COSMIC	1.787	Down-regulation
AGC_RSK_RSKp90_RPS6KA1_ST	P29317	EPHA2	Q15418	RPS6KA1	S901	R894Q	894	Missense	distal	-7	no	1.961	1.910	EPSD	ICGC;COSMIC	1.787	Down-regulation
AGC_RSK_RSKp90_RPS6KA1_ST	P29317	EPHA2	Q15418	RPS6KA1	S901	R907C	907	Missense	distal	6	no	1.961	1.783	EPSD	ICGC;GDSC	1.787	Loss
AGC_RSK_RSKp90_RPS6KA1_ST	P29317	EPHA2	Q15418	RPS6KA1	S901	P905S	905	Missense	distal	4	no	1.961	1.935	EPSD	ICGC	1.787	Down-regulation
AGC_RSK_RSKp90_RPS6KA1_ST	P23588	EIF4B	Q15418	RPS6KA1	S183	R188C	188	Missense	distal	5	no	2.232	2.031	EPSD	ICGC;COSMIC	1.787	Down-regulation
AGC_RSK_RSKp90_RPS6KA1_ST	P23588	EIF4B	Q15418	RPS6KA1	S183	R188H	188	Missense	distal	5	no	2.232	1.885	EPSD	ICGC;COSMIC	1.787	Down-regulation
AGC_RSK_RSKp90_RPS6KA1_ST	P23588	EIF4B	Q15418	RPS6KA1	S183	R186Q	186	Missense	distal	3	no	2.232	2.296	EPSD	ICGC;COSMIC	1.787	Up-regulation
AGC_RSK_RSKp90_RPS6KA1_ST	P16144	ITGB4	Q15418	RPS6KA1	T25	S19G	19	Missense	distal	-6	no	1.639	2.307	EPSD	ICGC;COSMIC	1.787	Gain
AGC_RSK_RSKp90_RPS6KA1_ST	P16144	ITGB4	Q15418	RPS6KA1	T168	D166N	166	Missense	proximal	-2	no	1.859	1.884	EPSD	ICGC	1.787	Up-regulation
AGC_RSK_RSKp90_RPS6KA1_ST	P16144	ITGB4	Q15418	RPS6KA1	T168	L163I	163	Missense	distal	-5	no	1.859	1.722	EPSD	ICGC;COSMIC	1.787	Loss
AGC_RSK_RSKp90_RPS6KA1_ST	P16144	ITGB4	Q15418	RPS6KA1	S368	R367C	367	Missense	proximal	-1	no	1.660	1.923	EPSD	ICGC;COSMIC	1.787	Gain
AGC_RSK_RSKp90_RPS6KA1_ST	P16144	ITGB4	Q15418	RPS6KA1	S1118	P1121S	1121	Missense	distal	3	no	2.522	2.458	EPSD	ICGC	1.787	Down-regulation
AGC_RSK_RSKp90_RPS6KA1_ST	P16144	ITGB4	Q15418	RPS6KA1	S1119	P1121S	1121	Missense	proximal	2	no	3.006	2.828	EPSD	ICGC	1.787	Down-regulation
AGC_RSK_RSKp90_RPS6KA1_ST	Q9HC62	SENP2	Q15418	RPS6KA1	S168	G164V	164	Missense	distal	-4	no	2.257	2.157	EPSD	ICGC	1.787	Down-regulation
AGC_RSK_RSKp90_RPS6KA1_ST	P01100	FOS	Q15418	RPS6KA1	S122	G127C	127	Missense	distal	5	no	1.778	2.016	EPSD	ICGC;COSMIC	1.787	Gain
AGC_RSK_RSKp90_RPS6KA1_ST	P01100	FOS	Q15418	RPS6KA1	S281	R287H	287	Missense	distal	6	no	1.813	1.834	EPSD	ICGC;COSMIC	1.787	Up-regulation
AGC_RSK_RSKp90_RPS6KA1_ST	Q96RK0	CIC	Q15418	RPS6KA1	T328	A330S	330	Missense	proximal	2	no	1.900	2.094	EPSD	ICGC	1.787	Up-regulation
AGC_RSK_RSKp90_RPS6KA1_ST	Q96RK0	CIC	Q15418	RPS6KA1	T328	S325I	325	Missense	distal	-3	no	1.900	2.178	EPSD	ICGC	1.787	Up-regulation
AGC_RSK_RSKp90_RPS6KA1_ST	Q96RK0	CIC	Q15418	RPS6KA1	T328	T322I	322	Missense	distal	-6	no	1.900	1.464	EPSD	ICGC	1.787	Loss
AGC_RSK_RSKp90_RPS6KA1_ST	Q96RK0	CIC	Q15418	RPS6KA1	T328	S333N	333	Missense	distal	5	no	1.900	1.808	EPSD	ICGC	1.787	Down-regulation
AGC_RSK_RSKp90_RPS6KA1_ST	Q96RK0	CIC	Q15418	RPS6KA1	S333	A330S	330	Missense	distal	-3	no	2.187	1.789	EPSD	ICGC	1.787	Down-regulation
AGC_RSK_RSKp90_RPS6KA1_ST	Q96RK0	CIC	Q15418	RPS6KA1	S333	R340Q	340	Missense	distal	7	no	2.187	2.145	EPSD	ICGC;COSMIC	1.787	Down-regulation
AGC_RSK_RSKp90_RPS6KA1_ST	Q96RK0	CIC	Q15418	RPS6KA1	S333	S333N	333	Missense	central	0	yes	2.187	0.000	EPSD	ICGC	1.787	Loss
AGC_RSK_RSKp90_RPS6KA1_ST	Q96RK0	CIC	Q15418	RPS6KA1	S333	C336R	336	Missense	distal	3	no	2.187	2.098	EPSD	ICGC	1.787	Down-regulation
AGC_RSK_RSKp90_RPS6KA1_ST	Q96RK0	CIC	Q15418	RPS6KA1	T421	P417R	417	Missense	distal	-4	no	1.933	1.879	EPSD	ICGC	1.787	Down-regulation
AGC_RSK_RSKp90_RPS6KA1_ST	Q96RK0	CIC	Q15418	RPS6KA1	T421	R428L	428	Missense	distal	7	no	1.933	1.834	EPSD	ICGC	1.787	Down-regulation
AGC_RSK_RSKp90_RPS6KA1_ST	Q96RK0	CIC	Q15418	RPS6KA1	T421	R415Q	415	Missense	distal	-6	no	1.933	2.318	EPSD	ICGC;COSMIC	1.787	Up-regulation
AGC_RSK_RSKp90_RPS6KA1_ST	Q96RK0	CIC	Q15418	RPS6KA1	T421	A423S	423	Missense	proximal	2	no	1.933	2.127	EPSD	ICGC	1.787	Up-regulation
AGC_RSK_RSKp90_RPS6KA1_ST	Q96RK0	CIC	Q15418	RPS6KA1	T421	S426P	426	Missense	distal	5	no	1.933	1.936	EPSD	ICGC;COSMIC	1.787	Up-regulation
AGC_RSK_RSKp90_RPS6KA1_ST	Q96RK0	CIC	Q15418	RPS6KA1	T421	R425C	425	Missense	distal	4	no	1.933	1.948	EPSD	ICGC	1.787	Up-regulation
AGC_RSK_RSKp90_RPS6KA1_ST	Q96RK0	CIC	Q15418	RPS6KA1	T421	Q427H	427	Missense	distal	6	no	1.933	2.006	EPSD	ICGC;COSMIC	1.787	Up-regulation
AGC_RSK_RSKp90_RPS6KA1_ST	Q96RK0	CIC	Q15418	RPS6KA1	S424	A423S	423	Missense	proximal	-1	no	1.660	1.907	EPSD	ICGC	1.787	Gain
AGC_RSK_RSKp90_RPS6KA1_ST	Q96RK0	CIC	Q15418	RPS6KA1	S424	S426P	426	Missense	proximal	2	no	1.660	1.839	EPSD	ICGC;COSMIC	1.787	Gain
AGC_RSK_RSKp90_RPS6KA1_ST	Q96RK0	CIC	Q15418	RPS6KA1	S431	R428L	428	Missense	distal	-3	no	2.264	2.348	EPSD	ICGC	1.787	Up-regulation
AGC_RSK_RSKp90_RPS6KA1_ST	Q96RK0	CIC	Q15418	RPS6KA1	S431	A429S	429	Missense	proximal	-2	no	2.264	2.289	EPSD	ICGC	1.787	Up-regulation
AGC_RSK_RSKp90_RPS6KA1_ST	Q96RK0	CIC	Q15418	RPS6KA1	S431	D433Y	433	Missense	proximal	2	no	2.264	2.288	EPSD	ICGC	1.787	Up-regulation
AGC_RSK_RSKp90_RPS6KA1_ST	Q96RK0	CIC	Q15418	RPS6KA1	S431	S431I	431	Missense	central	0	yes	2.264	0.000	EPSD	ICGC	1.787	Loss
AGC_RSK_RSKp90_RPS6KA1_ST	Q96RK0	CIC	Q15418	RPS6KA1	S431	S426P	426	Missense	distal	-5	no	2.264	2.398	EPSD	ICGC;COSMIC	1.787	Up-regulation
AGC_RSK_RSKp90_RPS6KA1_ST	Q96RK0	CIC	Q15418	RPS6KA1	S431	R425C	425	Missense	distal	-6	no	2.264	2.741	EPSD	ICGC	1.787	Up-regulation
AGC_RSK_RSKp90_RPS6KA1_ST	Q96RK0	CIC	Q15418	RPS6KA1	S431	Q427H	427	Missense	distal	-4	no	2.264	2.218	EPSD	ICGC;COSMIC	1.787	Down-regulation
AGC_RSK_RSKp90_RPS6KA1_ST	Q96RK0	CIC	Q15418	RPS6KA1	S431	S431N	431	Missense	central	0	yes	2.264	0.000	EPSD	ICGC;COSMIC	1.787	Loss
AGC_RSK_RSKp90_RPS6KA1_ST	Q96RK0	CIC	Q15418	RPS6KA1	S431	T435M	435	Missense	distal	4	no	2.264	2.243	EPSD	ICGC;COSMIC	1.787	Down-regulation
AGC_RSK_RSKp90_RPS6KA1_ST	Q96RK0	CIC	Q15418	RPS6KA1	S479	E485D	485	Missense	distal	6	no	2.030	1.859	EPSD	ICGC;COSMIC	1.787	Down-regulation
AGC_RSK_RSKp90_RPS6KA1_ST	Q96RK0	CIC	Q15418	RPS6KA1	S479	G477W	477	Missense	proximal	-2	no	2.030	1.969	EPSD	ICGC;COSMIC	1.787	Down-regulation
AGC_RSK_RSKp90_RPS6KA1_ST	Q96RK0	CIC	Q15418	RPS6KA1	S479	D483G	483	Missense	distal	4	no	2.030	2.075	EPSD	ICGC;COSMIC	1.787	Up-regulation
AGC_RSK_RSKp90_RPS6KA1_ST	Q96RK0	CIC	Q15418	RPS6KA1	T567	A568V	568	Missense	proximal	1	no	1.902	1.767	EPSD	ICGC;COSMIC	1.787	Loss
AGC_RSK_RSKp90_RPS6KA1_ST	Q96RK0	CIC	Q15418	RPS6KA1	T567	S562Y	562	Missense	distal	-5	no	1.902	2.020	EPSD	ICGC	1.787	Up-regulation
AGC_RSK_RSKp90_RPS6KA1_ST	Q96RK0	CIC	Q15418	RPS6KA1	S585	G580C	580	Missense	distal	-5	no	2.007	2.090	EPSD	ICGC;COSMIC	1.787	Up-regulation
AGC_RSK_RSKp90_RPS6KA1_ST	Q96RK0	CIC	Q15418	RPS6KA1	S894	Q901H	901	Missense	distal	7	no	2.127	1.983	EPSD	ICGC;COSMIC	1.787	Down-regulation
AGC_RSK_RSKp90_RPS6KA1_ST	Q96RK0	CIC	Q15418	RPS6KA1	S1163	V1165L	1165	Missense	proximal	2	no	2.471	2.352	EPSD	ICGC	1.787	Down-regulation
AGC_RSK_RSKp90_RPS6KA1_ST	Q96RK0	CIC	Q15418	RPS6KA1	S1163	Q1170R	1170	Missense	distal	7	no	2.471	2.512	EPSD	ICGC	1.787	Up-regulation
AGC_RSK_RSKp90_RPS6KA1_ST	Q96RK0	CIC	Q15418	RPS6KA1	S1163	P1167H	1167	Missense	distal	4	no	2.471	2.487	EPSD	ICGC;COSMIC	1.787	Up-regulation
AGC_RSK_RSKp90_RPS6KA1_ST	Q96RK0	CIC	Q15418	RPS6KA1	T1217	V1213I	1213	Missense	distal	-4	no	1.925	2.020	EPSD	ICGC	1.787	Up-regulation
AGC_RSK_RSKp90_RPS6KA1_ST	Q96RK0	CIC	Q15418	RPS6KA1	S1246	W1239C	1239	Missense	distal	-7	no	2.501	2.494	EPSD	ICGC	1.787	Down-regulation
AGC_RSK_RSKp90_RPS6KA1_ST	P25963	NFKBIA	Q15418	RPS6KA1	S32	D31G	31	Missense	proximal	-1	no	1.718	1.837	PhosphoSitePlus	ICGC;COSMIC	1.787	Gain
TK_PDGFR_PDGFRA_Y	P16234	PDGFRA	P16234	PDGFRA	Y572	P567L	567	Missense	distal	-5	no	13.678	14.171	EPSD;PhosphoSitePlus	ICGC;COSMIC	8.840	Up-regulation
TK_PDGFR_PDGFRA_Y	P16234	PDGFRA	P16234	PDGFRA	Y572	D576G	576	Missense	distal	4	no	13.678	13.690	EPSD;PhosphoSitePlus	ICGC;COSMIC	8.840	Up-regulation
TK_PDGFR_PDGFRA_Y	P16234	PDGFRA	P16234	PDGFRA	Y574	P567L	567	Missense	distal	-7	no	13.819	14.084	EPSD;PhosphoSitePlus	ICGC;COSMIC	8.840	Up-regulation
TK_PDGFR_PDGFRA_Y	P16234	PDGFRA	P16234	PDGFRA	Y574	D576G	576	Missense	proximal	2	no	13.819	15.007	EPSD;PhosphoSitePlus	ICGC;COSMIC	8.840	Up-regulation
TK_PDGFR_PDGFRA_Y	P16234	PDGFRA	P16234	PDGFRA	Y720	E726K	726	Missense	distal	6	no	14.620	14.278	EPSD	ICGC	8.840	Down-regulation
TK_PDGFR_PDGFRA_Y	P16234	PDGFRA	P16234	PDGFRA	Y731	E726K	726	Missense	distal	-5	no	14.394	15.187	EPSD	ICGC	8.840	Up-regulation
TK_PDGFR_PDGFRA_Y	P16234	PDGFRA	P16234	PDGFRA	Y742	M745I	745	Missense	distal	3	no	23.643	24.064	EPSD	ICGC;COSMIC	8.840	Up-regulation
TK_PDGFR_PDGFRA_Y	P16234	PDGFRA	P16234	PDGFRA	Y742	T739I	739	Missense	distal	-3	no	23.643	23.665	EPSD	ICGC;COSMIC	8.840	Up-regulation
TK_PDGFR_PDGFRA_Y	P16234	PDGFRA	P16234	PDGFRA	Y754	L761F	761	Missense	distal	7	no	20.901	21.008	EPSD	ICGC;COSMIC	8.840	Up-regulation
TK_PDGFR_PDGFRA_Y	P16234	PDGFRA	P16234	PDGFRA	Y754	D756N	756	Missense	proximal	2	no	20.901	21.462	EPSD	ICGC;COSMIC;CCLE	8.840	Up-regulation
TK_PDGFR_PDGFRA_Y	P16234	PDGFRA	P16234	PDGFRA	Y754	S755F	755	Missense	proximal	1	no	20.901	21.369	EPSD	ICGC;COSMIC	8.840	Up-regulation
TK_PDGFR_PDGFRA_Y	P16234	PDGFRA	P16234	PDGFRA	Y762	L761F	761	Missense	proximal	-1	no	14.790	14.750	EPSD	ICGC;COSMIC	8.840	Down-regulation
TK_PDGFR_PDGFRA_Y	P16234	PDGFRA	P16234	PDGFRA	Y762	D756N	756	Missense	distal	-6	no	14.790	15.405	EPSD	ICGC;COSMIC;CCLE	8.840	Up-regulation
TK_PDGFR_PDGFRA_Y	P16234	PDGFRA	P16234	PDGFRA	Y762	Y762H	762	Missense	central	0	yes	14.790	0.000	EPSD	ICGC;COSMIC	8.840	Loss
TK_PDGFR_PDGFRA_Y	P16234	PDGFRA	P16234	PDGFRA	Y762	S755F	755	Missense	distal	-7	no	14.790	13.242	EPSD	ICGC;COSMIC	8.840	Down-regulation
TK_PDGFR_PDGFRA_Y	P16234	PDGFRA	P16234	PDGFRA	Y768	L761F	761	Missense	distal	-7	no	14.461	13.275	EPSD	ICGC;COSMIC	8.840	Down-regulation
TK_PDGFR_PDGFRA_Y	P16234	PDGFRA	P16234	PDGFRA	Y768	Y762H	762	Missense	distal	-6	no	14.461	12.716	EPSD	ICGC;COSMIC	8.840	Down-regulation
TK_PDGFR_PDGFRA_Y	P16234	PDGFRA	P16234	PDGFRA	Y849	M844I	844	Missense	distal	-5	no	9.824	8.939	EPSD	ICGC;COSMIC	8.840	Down-regulation
TK_PDGFR_PDGFRA_Y	P16234	PDGFRA	P16234	PDGFRA	Y849	D842G	842	Missense	distal	-7	no	9.824	9.951	EPSD	ICGC	8.840	Up-regulation
TK_PDGFR_PDGFRA_Y	P16234	PDGFRA	P16234	PDGFRA	Y849	N848K	848	Missense	proximal	-1	no	9.824	9.839	EPSD	ICGC;COSMIC	8.840	Up-regulation
TK_PDGFR_PDGFRA_Y	P16234	PDGFRA	P16234	PDGFRA	Y849	Y849S	849	Missense	central	0	yes	9.824	0.000	EPSD	ICGC;COSMIC	8.840	Loss
TK_PDGFR_PDGFRA_Y	P16234	PDGFRA	P16234	PDGFRA	Y988	G990C	990	Missense	proximal	2	no	24.666	25.524	EPSD;PhosphoSitePlus	ICGC	8.840	Up-regulation
TK_PDGFR_PDGFRA_Y	P16234	PDGFRA	P16234	PDGFRA	Y1018	R1011I	1011	Missense	distal	-7	no	20.400	19.436	PhosphoSitePlus;EPSD	ICGC;COSMIC	8.840	Down-regulation
TK_PDGFR_PDGFRA_Y	P16234	PDGFRA	P16234	PDGFRA	Y1018	L1012P	1012	Missense	distal	-6	no	20.400	20.864	PhosphoSitePlus;EPSD	ICGC;COSMIC	8.840	Up-regulation
TK_PDGFR_PDGFRA_Y	Q9P219	CCDC88C	P16234	PDGFRA	Y1395	Y1395C	1395	Missense	central	0	yes	9.006	0.000	EPSD	ICGC;COSMIC	8.840	Loss
TK_PDGFR_PDGFRA_Y	Q9P219	CCDC88C	P16234	PDGFRA	Y1395	P1397H	1397	Missense	proximal	2	no	9.006	8.126	EPSD	ICGC;COSMIC	8.840	Loss
TK_PDGFR_PDGFRA_Y	P12931	SRC	P16234	PDGFRA	Y419	G424C	424	Missense	distal	5	no	18.156	16.849	PhosphoSitePlus	ICGC;COSMIC	8.840	Down-regulation
TK_PDGFR_PDGFRA_Y	P12931	SRC	P16234	PDGFRA	Y419	R422W	422	Missense	distal	3	no	18.156	17.456	PhosphoSitePlus	ICGC	8.840	Down-regulation
AGC_GRK_BARK_GRK2_ST	P35241	RDX	P25098	GRK2	T564	A557E	557	Missense	distal	-7	no	167.189	168.616	PhosphoSitePlus	ICGC	128.034	Up-regulation
AGC_GRK_BARK_GRK2_ST	P41143	OPRD1	P25098	GRK2	S344	E350K	350	Missense	distal	6	no	141.487	137.653	EPSD	ICGC;COSMIC	128.034	Down-regulation
AGC_GRK_BARK_GRK2_ST	P41143	OPRD1	P25098	GRK2	S344	S346N	346	Missense	proximal	2	no	141.487	142.158	EPSD	ICGC	128.034	Up-regulation
AGC_GRK_BARK_GRK2_ST	P41143	OPRD1	P25098	GRK2	S344	R349H	349	Missense	distal	5	no	141.487	140.797	EPSD	ICGC	128.034	Down-regulation
AGC_GRK_BARK_GRK2_ST	P41143	OPRD1	P25098	GRK2	S344	A348S	348	Missense	distal	4	no	141.487	144.714	EPSD	ICGC	128.034	Up-regulation
AGC_GRK_BARK_GRK2_ST	P41143	OPRD1	P25098	GRK2	S344	D341A	341	Missense	distal	-3	no	141.487	125.232	EPSD	ICGC	128.034	Loss
AGC_GRK_BARK_GRK2_ST	P41143	OPRD1	P25098	GRK2	T358	A359T	359	Missense	proximal	1	no	155.406	157.538	EPSD	ICGC	128.034	Up-regulation
AGC_GRK_BARK_GRK2_ST	P41143	OPRD1	P25098	GRK2	T358	P362L	362	Missense	distal	4	no	155.406	144.592	EPSD	ICGC;COSMIC	128.034	Down-regulation
AGC_GRK_BARK_GRK2_ST	P41143	OPRD1	P25098	GRK2	T358	G365S	365	Missense	distal	7	no	155.406	155.343	EPSD	ICGC	128.034	Down-regulation
AGC_GRK_BARK_GRK2_ST	P41143	OPRD1	P25098	GRK2	T361	G368S	368	Missense	distal	7	no	152.449	152.387	EPSD	ICGC;COSMIC	128.034	Down-regulation
AGC_GRK_BARK_GRK2_ST	P41143	OPRD1	P25098	GRK2	T361	A359T	359	Missense	proximal	-2	no	152.449	159.624	EPSD	ICGC	128.034	Up-regulation
AGC_GRK_BARK_GRK2_ST	P41143	OPRD1	P25098	GRK2	T361	P362L	362	Missense	proximal	1	no	152.449	154.497	EPSD	ICGC;COSMIC	128.034	Up-regulation
AGC_GRK_BARK_GRK2_ST	P41143	OPRD1	P25098	GRK2	T361	G365S	365	Missense	distal	4	no	152.449	155.823	EPSD	ICGC	128.034	Up-regulation
AGC_GRK_BARK_GRK2_ST	P41143	OPRD1	P25098	GRK2	S363	G368S	368	Missense	distal	5	no	149.684	150.183	PhosphoSitePlus	ICGC;COSMIC	128.034	Up-regulation
AGC_GRK_BARK_GRK2_ST	P41143	OPRD1	P25098	GRK2	S363	A359T	359	Missense	distal	-4	no	149.684	165.997	PhosphoSitePlus	ICGC	128.034	Up-regulation
AGC_GRK_BARK_GRK2_ST	P41143	OPRD1	P25098	GRK2	S363	P362L	362	Missense	proximal	-1	no	149.684	136.028	PhosphoSitePlus	ICGC;COSMIC	128.034	Down-regulation
AGC_GRK_BARK_GRK2_ST	P41143	OPRD1	P25098	GRK2	S363	G365S	365	Missense	proximal	2	no	149.684	147.359	PhosphoSitePlus	ICGC	128.034	Down-regulation
AGC_GRK_BARK_GRK2_ST	P15311	EZR	P25098	GRK2	T332	E334K	334	Missense	proximal	2	no	146.185	141.493	EPSD	ICGC;COSMIC	128.034	Down-regulation
AGC_GRK_BARK_GRK2_ST	P15311	EZR	P25098	GRK2	S366	A361E	361	Missense	distal	-5	no	126.864	135.287	EPSD	ICGC	128.034	Gain
AGC_GRK_BARK_GRK2_ST	P15311	EZR	P25098	GRK2	S539	T533M	533	Missense	distal	-6	no	126.245	133.401	EPSD	ICGC	128.034	Gain
AGC_GRK_BARK_GRK2_ST	P15311	EZR	P25098	GRK2	T548	E544Q	544	Missense	distal	-4	no	143.837	138.605	EPSD	ICGC	128.034	Down-regulation
AGC_GRK_BARK_GRK2_ST	P15311	EZR	P25098	GRK2	T567	T567M	567	Missense	central	0	yes	162.201	0.000	PhosphoSitePlus	ICGC;COSMIC	128.034	Loss
AGC_GRK_BARK_GRK2_ST	P15311	EZR	P25098	GRK2	T567	Q573K	573	Missense	distal	6	no	162.201	159.709	PhosphoSitePlus	ICGC	128.034	Down-regulation
AGC_GRK_BARK_GRK2_ST	P15311	EZR	P25098	GRK2	T576	R579H	579	Missense	distal	3	no	131.411	130.640	EPSD	ICGC;COSMIC	128.034	Down-regulation
AGC_GRK_BARK_GRK2_ST	P15311	EZR	P25098	GRK2	T576	N575K	575	Missense	proximal	-1	no	131.411	118.676	EPSD	ICGC	128.034	Loss
AGC_GRK_BARK_GRK2_ST	P15311	EZR	P25098	GRK2	T576	Q573K	573	Missense	distal	-3	no	131.411	119.935	EPSD	ICGC	128.034	Loss
AGC_GRK_BARK_GRK2_ST	P07550	ADRB2	P25098	GRK2	S355	N352H	352	Missense	distal	-3	no	139.357	130.151	EPSD;PhosphoSitePlus	ICGC	128.034	Down-regulation
AGC_GRK_BARK_GRK2_ST	P07550	ADRB2	P25098	GRK2	S356	N352H	352	Missense	distal	-4	no	164.244	150.926	EPSD;PhosphoSitePlus	ICGC	128.034	Down-regulation
AGC_GRK_BARK_GRK2_ST	P07550	ADRB2	P25098	GRK2	T384	P382L	382	Missense	proximal	-2	no	151.353	147.323	EPSD;PhosphoSitePlus	ICGC;COSMIC	128.034	Down-regulation
AGC_GRK_BARK_GRK2_ST	P07550	ADRB2	P25098	GRK2	T384	T384M	384	Missense	central	0	yes	151.353	0.000	EPSD;PhosphoSitePlus	ICGC	128.034	Loss
AGC_GRK_BARK_GRK2_ST	P07550	ADRB2	P25098	GRK2	T393	D400Y	400	Missense	distal	7	no	129.526	130.173	EPSD	ICGC	128.034	Up-regulation
AGC_GRK_BARK_GRK2_ST	P07550	ADRB2	P25098	GRK2	S396	D400Y	400	Missense	distal	4	no	164.934	161.113	PhosphoSitePlus;EPSD	ICGC	128.034	Down-regulation
AGC_GRK_BARK_GRK2_ST	P07550	ADRB2	P25098	GRK2	S401	N405I	405	Missense	distal	4	no	165.208	163.128	EPSD;PhosphoSitePlus	ICGC	128.034	Down-regulation
AGC_GRK_BARK_GRK2_ST	P07550	ADRB2	P25098	GRK2	S401	D400Y	400	Missense	proximal	-1	no	165.208	163.235	EPSD;PhosphoSitePlus	ICGC	128.034	Down-regulation
AGC_GRK_BARK_GRK2_ST	P07550	ADRB2	P25098	GRK2	S407	N405I	405	Missense	proximal	-2	no	147.963	133.169	EPSD;PhosphoSitePlus	ICGC	128.034	Down-regulation
AGC_GRK_BARK_GRK2_ST	P07550	ADRB2	P25098	GRK2	S407	D400Y	400	Missense	distal	-7	no	147.963	150.728	EPSD;PhosphoSitePlus	ICGC	128.034	Up-regulation
AGC_GRK_BARK_GRK2_ST	P07550	ADRB2	P25098	GRK2	T408	N405I	405	Missense	distal	-3	no	132.393	104.689	EPSD	ICGC	128.034	Loss
AGC_GRK_BARK_GRK2_ST	P07550	ADRB2	P25098	GRK2	S411	N405I	405	Missense	distal	-6	no	154.701	145.932	EPSD;PhosphoSitePlus	ICGC	128.034	Down-regulation
AGC_GRK_BARK_GRK2_ST	Q14940	SLC9A5	P25098	GRK2	S321	A318T	318	Missense	distal	-3	no	115.185	131.644	EPSD	ICGC	128.034	Gain
AGC_GRK_BARK_GRK2_ST	Q14940	SLC9A5	P25098	GRK2	T681	N677D	677	Missense	distal	-4	no	123.011	134.865	EPSD	ICGC;COSMIC	128.034	Gain
AGC_GRK_BARK_GRK2_ST	Q14940	SLC9A5	P25098	GRK2	S702	V696L	696	Missense	distal	-6	no	134.734	126.322	EPSD;PhosphoSitePlus	ICGC	128.034	Loss
AGC_GRK_BARK_GRK2_ST	Q14940	SLC9A5	P25098	GRK2	S702	E707D	707	Missense	distal	5	no	134.734	134.006	EPSD;PhosphoSitePlus	ICGC	128.034	Down-regulation
AGC_GRK_BARK_GRK2_ST	Q14940	SLC9A5	P25098	GRK2	S709	E707D	707	Missense	proximal	-2	no	157.087	160.293	EPSD;PhosphoSitePlus	ICGC	128.034	Up-regulation
AGC_GRK_BARK_GRK2_ST	Q14940	SLC9A5	P25098	GRK2	S711	E707D	707	Missense	distal	-4	no	155.358	165.099	EPSD;PhosphoSitePlus	ICGC	128.034	Up-regulation
AGC_GRK_BARK_GRK2_ST	Q14940	SLC9A5	P25098	GRK2	S712	E707D	707	Missense	distal	-5	no	154.074	153.149	PhosphoSitePlus;EPSD	ICGC	128.034	Down-regulation
AGC_GRK_BARK_GRK2_ST	Q14940	SLC9A5	P25098	GRK2	T714	E707D	707	Missense	distal	-7	no	178.110	176.415	EPSD;PhosphoSitePlus	ICGC	128.034	Down-regulation
AGC_GRK_BARK_GRK2_ST	Q14940	SLC9A5	P25098	GRK2	S741	P746L	746	Missense	distal	5	no	142.504	138.930	EPSD	ICGC;COSMIC	128.034	Down-regulation
AGC_GRK_BARK_GRK2_ST	Q14940	SLC9A5	P25098	GRK2	S741	L742P	742	Missense	proximal	1	no	142.504	140.456	EPSD	ICGC;COSMIC	128.034	Down-regulation
AGC_GRK_BARK_GRK2_ST	Q14940	SLC9A5	P25098	GRK2	S741	G736V	736	Missense	distal	-5	no	142.504	139.470	EPSD	ICGC	128.034	Down-regulation
AGC_GRK_BARK_GRK2_ST	Q14940	SLC9A5	P25098	GRK2	S741	E743K	743	Missense	proximal	2	no	142.504	137.812	EPSD	ICGC	128.034	Down-regulation
AGC_GRK_BARK_GRK2_ST	P08172	CHRM2	P25098	GRK2	S232	A226G	226	Missense	distal	-6	no	135.315	134.343	EPSD;PhosphoSitePlus	ICGC	128.034	Down-regulation
AGC_GRK_BARK_GRK2_ST	P08172	CHRM2	P25098	GRK2	S232	S234I	234	Missense	proximal	2	no	135.315	126.251	EPSD;PhosphoSitePlus	ICGC	128.034	Loss
AGC_GRK_BARK_GRK2_ST	P08172	CHRM2	P25098	GRK2	S232	V231I	231	Missense	proximal	-1	no	135.315	122.596	EPSD;PhosphoSitePlus	ICGC;COSMIC	128.034	Loss
AGC_GRK_BARK_GRK2_ST	P08172	CHRM2	P25098	GRK2	S232	V225F	225	Missense	distal	-7	no	135.315	133.113	EPSD;PhosphoSitePlus	ICGC	128.034	Down-regulation
AGC_GRK_BARK_GRK2_ST	P08172	CHRM2	P25098	GRK2	S232	Q228E	228	Missense	distal	-4	no	135.315	140.547	EPSD;PhosphoSitePlus	ICGC;COSMIC	128.034	Up-regulation
AGC_GRK_BARK_GRK2_ST	P08172	CHRM2	P25098	GRK2	S234	S234I	234	Missense	central	0	yes	135.010	0.000	EPSD;PhosphoSitePlus	ICGC	128.034	Loss
AGC_GRK_BARK_GRK2_ST	P08172	CHRM2	P25098	GRK2	S234	V231I	231	Missense	distal	-3	no	135.010	119.272	EPSD;PhosphoSitePlus	ICGC;COSMIC	128.034	Loss
AGC_GRK_BARK_GRK2_ST	P08172	CHRM2	P25098	GRK2	S234	Q228E	228	Missense	distal	-6	no	135.010	133.819	EPSD;PhosphoSitePlus	ICGC;COSMIC	128.034	Down-regulation
AGC_GRK_BARK_GRK2_ST	P08172	CHRM2	P25098	GRK2	S250	D253G	253	Missense	distal	3	no	154.968	155.747	EPSD;PhosphoSitePlus	ICGC;COSMIC	128.034	Up-regulation
AGC_GRK_BARK_GRK2_ST	P08172	CHRM2	P25098	GRK2	S250	M248K	248	Missense	proximal	-2	no	154.968	159.487	EPSD;PhosphoSitePlus	ICGC;COSMIC	128.034	Up-regulation
AGC_GRK_BARK_GRK2_ST	P08172	CHRM2	P25098	GRK2	S251	D253G	253	Missense	proximal	2	no	143.627	143.497	EPSD;PhosphoSitePlus	ICGC;COSMIC	128.034	Down-regulation
AGC_GRK_BARK_GRK2_ST	P08172	CHRM2	P25098	GRK2	S251	M248K	248	Missense	distal	-3	no	143.627	127.315	EPSD;PhosphoSitePlus	ICGC;COSMIC	128.034	Loss
AGC_GRK_BARK_GRK2_ST	P08172	CHRM2	P25098	GRK2	T271	C274G	274	Missense	distal	3	no	142.748	140.301	EPSD;PhosphoSitePlus	ICGC;COSMIC	128.034	Down-regulation
AGC_GRK_BARK_GRK2_ST	P08172	CHRM2	P25098	GRK2	T271	N273H	273	Missense	proximal	2	no	142.748	139.340	EPSD;PhosphoSitePlus	ICGC;COSMIC	128.034	Down-regulation
AGC_GRK_BARK_GRK2_ST	P08172	CHRM2	P25098	GRK2	T271	A265T	265	Missense	distal	-6	no	142.748	143.753	EPSD;PhosphoSitePlus	ICGC;COSMIC	128.034	Up-regulation
AGC_GRK_BARK_GRK2_ST	P08172	CHRM2	P25098	GRK2	T271	P269S	269	Missense	proximal	-2	no	142.748	146.914	EPSD;PhosphoSitePlus	ICGC;COSMIC;CCLE	128.034	Up-regulation
AGC_GRK_BARK_GRK2_ST	P08172	CHRM2	P25098	GRK2	T271	R267S	267	Missense	distal	-4	no	142.748	151.137	EPSD;PhosphoSitePlus	ICGC	128.034	Up-regulation
AGC_GRK_BARK_GRK2_ST	P08172	CHRM2	P25098	GRK2	T271	R267K	267	Missense	distal	-4	no	142.748	144.683	EPSD;PhosphoSitePlus	ICGC;COSMIC	128.034	Up-regulation
AGC_GRK_BARK_GRK2_ST	P08172	CHRM2	P25098	GRK2	T271	R267N	267	Missense	distal	-4	no	142.748	147.661	EPSD;PhosphoSitePlus	ICGC	128.034	Up-regulation
AGC_GRK_BARK_GRK2_ST	P08172	CHRM2	P25098	GRK2	T271	P266T	266	Missense	distal	-5	no	142.748	153.443	EPSD;PhosphoSitePlus	ICGC;COSMIC	128.034	Up-regulation
AGC_GRK_BARK_GRK2_ST	P08172	CHRM2	P25098	GRK2	S282	V289F	289	Missense	distal	7	no	152.972	153.095	EPSD;PhosphoSitePlus	ICGC;COSMIC	128.034	Up-regulation
AGC_GRK_BARK_GRK2_ST	P08172	CHRM2	P25098	GRK2	S282	E281K	281	Missense	proximal	-1	no	152.972	141.544	EPSD;PhosphoSitePlus	ICGC;COSMIC	128.034	Down-regulation
AGC_GRK_BARK_GRK2_ST	P08172	CHRM2	P25098	GRK2	S282	S283F	283	Missense	proximal	1	no	152.972	144.089	EPSD;PhosphoSitePlus	ICGC;COSMIC	128.034	Down-regulation
AGC_GRK_BARK_GRK2_ST	P08172	CHRM2	P25098	GRK2	S282	S282C	282	Missense	central	0	yes	152.972	0.000	EPSD;PhosphoSitePlus	ICGC;COSMIC	128.034	Loss
AGC_GRK_BARK_GRK2_ST	P08172	CHRM2	P25098	GRK2	S282	S286P	286	Missense	distal	4	no	152.972	149.957	EPSD;PhosphoSitePlus	ICGC	128.034	Down-regulation
AGC_GRK_BARK_GRK2_ST	P08172	CHRM2	P25098	GRK2	S282	E279D	279	Missense	distal	-3	no	152.972	149.766	EPSD;PhosphoSitePlus	ICGC;COSMIC	128.034	Down-regulation
AGC_GRK_BARK_GRK2_ST	P08172	CHRM2	P25098	GRK2	S283	V289F	289	Missense	distal	6	no	138.399	133.853	EPSD;PhosphoSitePlus	ICGC;COSMIC	128.034	Down-regulation
AGC_GRK_BARK_GRK2_ST	P08172	CHRM2	P25098	GRK2	S283	E281K	281	Missense	proximal	-2	no	138.399	132.890	EPSD;PhosphoSitePlus	ICGC;COSMIC	128.034	Down-regulation
AGC_GRK_BARK_GRK2_ST	P08172	CHRM2	P25098	GRK2	S283	S283F	283	Missense	central	0	yes	138.399	0.000	EPSD;PhosphoSitePlus	ICGC;COSMIC	128.034	Loss
AGC_GRK_BARK_GRK2_ST	P08172	CHRM2	P25098	GRK2	S283	S282C	282	Missense	proximal	-1	no	138.399	134.536	EPSD;PhosphoSitePlus	ICGC;COSMIC	128.034	Down-regulation
AGC_GRK_BARK_GRK2_ST	P08172	CHRM2	P25098	GRK2	S283	S286P	286	Missense	distal	3	no	138.399	141.397	EPSD;PhosphoSitePlus	ICGC	128.034	Up-regulation
AGC_GRK_BARK_GRK2_ST	P08172	CHRM2	P25098	GRK2	S283	E279D	279	Missense	distal	-4	no	138.399	148.140	EPSD;PhosphoSitePlus	ICGC;COSMIC	128.034	Up-regulation
AGC_GRK_BARK_GRK2_ST	P08172	CHRM2	P25098	GRK2	S286	V289F	289	Missense	distal	3	no	149.588	142.191	EPSD;PhosphoSitePlus	ICGC;COSMIC	128.034	Down-regulation
AGC_GRK_BARK_GRK2_ST	P08172	CHRM2	P25098	GRK2	S286	E281K	281	Missense	distal	-5	no	149.588	145.260	EPSD;PhosphoSitePlus	ICGC;COSMIC	128.034	Down-regulation
AGC_GRK_BARK_GRK2_ST	P08172	CHRM2	P25098	GRK2	S286	S283F	283	Missense	distal	-3	no	149.588	127.966	EPSD;PhosphoSitePlus	ICGC;COSMIC	128.034	Loss
AGC_GRK_BARK_GRK2_ST	P08172	CHRM2	P25098	GRK2	S286	S282C	282	Missense	distal	-4	no	149.588	145.443	EPSD;PhosphoSitePlus	ICGC;COSMIC	128.034	Down-regulation
AGC_GRK_BARK_GRK2_ST	P08172	CHRM2	P25098	GRK2	S286	S286P	286	Missense	central	0	yes	149.588	0.000	EPSD;PhosphoSitePlus	ICGC	128.034	Loss
AGC_GRK_BARK_GRK2_ST	P08172	CHRM2	P25098	GRK2	S286	E279D	279	Missense	distal	-7	no	149.588	147.893	EPSD;PhosphoSitePlus	ICGC;COSMIC	128.034	Down-regulation
AGC_GRK_BARK_GRK2_ST	P08172	CHRM2	P25098	GRK2	T287	V289F	289	Missense	proximal	2	no	162.650	157.343	EPSD;PhosphoSitePlus	ICGC;COSMIC	128.034	Down-regulation
AGC_GRK_BARK_GRK2_ST	P08172	CHRM2	P25098	GRK2	T287	E281K	281	Missense	distal	-6	no	162.650	157.951	EPSD;PhosphoSitePlus	ICGC;COSMIC	128.034	Down-regulation
AGC_GRK_BARK_GRK2_ST	P08172	CHRM2	P25098	GRK2	T287	S283F	283	Missense	distal	-4	no	162.650	154.872	EPSD;PhosphoSitePlus	ICGC;COSMIC	128.034	Down-regulation
AGC_GRK_BARK_GRK2_ST	P08172	CHRM2	P25098	GRK2	T287	S282C	282	Missense	distal	-5	no	162.650	159.998	EPSD;PhosphoSitePlus	ICGC;COSMIC	128.034	Down-regulation
AGC_GRK_BARK_GRK2_ST	P08172	CHRM2	P25098	GRK2	T287	S286P	286	Missense	proximal	-1	no	162.650	166.587	EPSD;PhosphoSitePlus	ICGC	128.034	Up-regulation
AGC_GRK_BARK_GRK2_ST	P08172	CHRM2	P25098	GRK2	S288	V289F	289	Missense	proximal	1	no	156.673	153.283	EPSD;PhosphoSitePlus	ICGC;COSMIC	128.034	Down-regulation
AGC_GRK_BARK_GRK2_ST	P08172	CHRM2	P25098	GRK2	S288	E281K	281	Missense	distal	-7	no	156.673	157.062	EPSD;PhosphoSitePlus	ICGC;COSMIC	128.034	Up-regulation
AGC_GRK_BARK_GRK2_ST	P08172	CHRM2	P25098	GRK2	S288	S283F	283	Missense	distal	-5	no	156.673	145.322	EPSD;PhosphoSitePlus	ICGC;COSMIC	128.034	Down-regulation
AGC_GRK_BARK_GRK2_ST	P08172	CHRM2	P25098	GRK2	S288	S282C	282	Missense	distal	-6	no	156.673	151.924	EPSD;PhosphoSitePlus	ICGC;COSMIC	128.034	Down-regulation
AGC_GRK_BARK_GRK2_ST	P08172	CHRM2	P25098	GRK2	S288	S286P	286	Missense	proximal	-2	no	156.673	152.507	EPSD;PhosphoSitePlus	ICGC	128.034	Down-regulation
AGC_GRK_BARK_GRK2_ST	P08172	CHRM2	P25098	GRK2	S290	V289F	289	Missense	proximal	-1	no	145.638	138.224	EPSD;PhosphoSitePlus	ICGC;COSMIC	128.034	Down-regulation
AGC_GRK_BARK_GRK2_ST	P08172	CHRM2	P25098	GRK2	S290	R297K	297	Missense	distal	7	no	145.638	145.460	EPSD;PhosphoSitePlus	ICGC	128.034	Down-regulation
AGC_GRK_BARK_GRK2_ST	P08172	CHRM2	P25098	GRK2	S290	S283F	283	Missense	distal	-7	no	145.638	145.076	EPSD;PhosphoSitePlus	ICGC;COSMIC	128.034	Down-regulation
AGC_GRK_BARK_GRK2_ST	P08172	CHRM2	P25098	GRK2	S290	S286P	286	Missense	distal	-4	no	145.638	136.053	EPSD;PhosphoSitePlus	ICGC	128.034	Down-regulation
AGC_GRK_BARK_GRK2_ST	P08172	CHRM2	P25098	GRK2	S294	V289F	289	Missense	distal	-5	no	138.400	127.870	EPSD;PhosphoSitePlus	ICGC;COSMIC	128.034	Loss
AGC_GRK_BARK_GRK2_ST	P08172	CHRM2	P25098	GRK2	S294	R297K	297	Missense	distal	3	no	138.400	135.334	EPSD;PhosphoSitePlus	ICGC	128.034	Down-regulation
AGC_GRK_BARK_GRK2_ST	P08172	CHRM2	P25098	GRK2	T302	T302P	302	Missense	central	0	yes	163.423	0.000	EPSD;PhosphoSitePlus	ICGC;CCLE	128.034	Loss
AGC_GRK_BARK_GRK2_ST	P08172	CHRM2	P25098	GRK2	T302	T307S	307	Missense	distal	5	no	163.423	166.581	EPSD;PhosphoSitePlus	ICGC;COSMIC	128.034	Up-regulation
AGC_GRK_BARK_GRK2_ST	P08172	CHRM2	P25098	GRK2	T302	D304N	304	Missense	proximal	2	no	163.423	161.638	EPSD;PhosphoSitePlus	ICGC;COSMIC	128.034	Down-regulation
AGC_GRK_BARK_GRK2_ST	P08172	CHRM2	P25098	GRK2	T302	R297K	297	Missense	distal	-5	no	163.423	160.640	EPSD;PhosphoSitePlus	ICGC	128.034	Down-regulation
AGC_GRK_BARK_GRK2_ST	P08172	CHRM2	P25098	GRK2	T302	E305K	305	Missense	distal	3	no	163.423	158.623	EPSD;PhosphoSitePlus	ICGC;COSMIC	128.034	Down-regulation
AGC_GRK_BARK_GRK2_ST	P08172	CHRM2	P25098	GRK2	T307	T302P	302	Missense	distal	-5	no	163.633	152.938	EPSD;PhosphoSitePlus	ICGC;CCLE	128.034	Down-regulation
AGC_GRK_BARK_GRK2_ST	P08172	CHRM2	P25098	GRK2	T307	L312Q	312	Missense	distal	5	no	163.633	168.412	EPSD;PhosphoSitePlus	ICGC;COSMIC	128.034	Up-regulation
AGC_GRK_BARK_GRK2_ST	P08172	CHRM2	P25098	GRK2	T307	D304N	304	Missense	distal	-3	no	163.633	160.356	EPSD;PhosphoSitePlus	ICGC;COSMIC	128.034	Down-regulation
AGC_GRK_BARK_GRK2_ST	P08172	CHRM2	P25098	GRK2	T307	S311F	311	Missense	distal	4	no	163.633	154.646	EPSD;PhosphoSitePlus	ICGC;COSMIC	128.034	Down-regulation
AGC_GRK_BARK_GRK2_ST	P08172	CHRM2	P25098	GRK2	T307	T302S	302	Missense	distal	-5	no	163.633	158.244	EPSD;PhosphoSitePlus	ICGC	128.034	Down-regulation
AGC_GRK_BARK_GRK2_ST	P08172	CHRM2	P25098	GRK2	T307	E305K	305	Missense	proximal	-2	no	163.633	158.124	EPSD;PhosphoSitePlus	ICGC;COSMIC	128.034	Down-regulation
AGC_GRK_BARK_GRK2_ST	P08172	CHRM2	P25098	GRK2	S309	T302P	302	Missense	distal	-7	no	154.235	153.685	EPSD;PhosphoSitePlus	ICGC;CCLE	128.034	Down-regulation
AGC_GRK_BARK_GRK2_ST	P08172	CHRM2	P25098	GRK2	S309	L312Q	312	Missense	distal	3	no	154.235	151.447	EPSD;PhosphoSitePlus	ICGC;COSMIC	128.034	Down-regulation
AGC_GRK_BARK_GRK2_ST	P08172	CHRM2	P25098	GRK2	S309	T307S	307	Missense	proximal	-2	no	154.235	158.684	EPSD;PhosphoSitePlus	ICGC;COSMIC	128.034	Up-regulation
AGC_GRK_BARK_GRK2_ST	P08172	CHRM2	P25098	GRK2	S309	D304N	304	Missense	distal	-5	no	154.235	148.353	EPSD;PhosphoSitePlus	ICGC;COSMIC	128.034	Down-regulation
AGC_GRK_BARK_GRK2_ST	P08172	CHRM2	P25098	GRK2	S309	S311F	311	Missense	proximal	2	no	154.235	152.742	EPSD;PhosphoSitePlus	ICGC;COSMIC	128.034	Down-regulation
AGC_GRK_BARK_GRK2_ST	P08172	CHRM2	P25098	GRK2	S309	T302S	302	Missense	distal	-7	no	154.235	150.380	EPSD;PhosphoSitePlus	ICGC	128.034	Down-regulation
AGC_GRK_BARK_GRK2_ST	P08172	CHRM2	P25098	GRK2	S309	E305K	305	Missense	distal	-4	no	154.235	149.143	EPSD;PhosphoSitePlus	ICGC;COSMIC	128.034	Down-regulation
AGC_GRK_BARK_GRK2_ST	P08172	CHRM2	P25098	GRK2	T310	L312Q	312	Missense	proximal	2	no	146.879	154.247	EPSD;PhosphoSitePlus	ICGC;COSMIC	128.034	Up-regulation
AGC_GRK_BARK_GRK2_ST	P08172	CHRM2	P25098	GRK2	T310	T307S	307	Missense	distal	-3	no	146.879	133.051	EPSD;PhosphoSitePlus	ICGC;COSMIC	128.034	Down-regulation
AGC_GRK_BARK_GRK2_ST	P08172	CHRM2	P25098	GRK2	T310	D304N	304	Missense	distal	-6	no	146.879	145.562	EPSD;PhosphoSitePlus	ICGC;COSMIC	128.034	Down-regulation
AGC_GRK_BARK_GRK2_ST	P08172	CHRM2	P25098	GRK2	T310	S311F	311	Missense	proximal	1	no	146.879	137.996	EPSD;PhosphoSitePlus	ICGC;COSMIC	128.034	Down-regulation
AGC_GRK_BARK_GRK2_ST	P08172	CHRM2	P25098	GRK2	T310	E305K	305	Missense	distal	-5	no	146.879	142.551	EPSD;PhosphoSitePlus	ICGC;COSMIC	128.034	Down-regulation
AGC_GRK_BARK_GRK2_ST	P08172	CHRM2	P25098	GRK2	S311	E318V	318	Missense	distal	7	no	143.703	143.790	PhosphoSitePlus;EPSD	ICGC	128.034	Up-regulation
AGC_GRK_BARK_GRK2_ST	P08172	CHRM2	P25098	GRK2	S311	L312Q	312	Missense	proximal	1	no	143.703	146.932	PhosphoSitePlus;EPSD	ICGC;COSMIC	128.034	Up-regulation
AGC_GRK_BARK_GRK2_ST	P08172	CHRM2	P25098	GRK2	S311	T307S	307	Missense	distal	-4	no	143.703	144.097	PhosphoSitePlus;EPSD	ICGC;COSMIC	128.034	Up-regulation
AGC_GRK_BARK_GRK2_ST	P08172	CHRM2	P25098	GRK2	S311	D304N	304	Missense	distal	-7	no	143.703	144.962	PhosphoSitePlus;EPSD	ICGC;COSMIC	128.034	Up-regulation
AGC_GRK_BARK_GRK2_ST	P08172	CHRM2	P25098	GRK2	S311	S311F	311	Missense	central	0	yes	143.703	0.000	PhosphoSitePlus;EPSD	ICGC;COSMIC	128.034	Loss
AGC_GRK_BARK_GRK2_ST	P08172	CHRM2	P25098	GRK2	S311	E305K	305	Missense	distal	-6	no	143.703	139.005	PhosphoSitePlus;EPSD	ICGC;COSMIC	128.034	Down-regulation
AGC_GRK_BARK_GRK2_ST	P35372	OPRM1	P25098	GRK2	S365	N359D	359	Missense	distal	-6	no	127.521	128.839	EPSD	ICGC;COSMIC	128.034	Gain
AGC_GRK_BARK_GRK2_ST	P35372	OPRM1	P25098	GRK2	T372	R373T	373	Missense	proximal	1	no	146.811	139.224	EPSD	ICGC;COSMIC	128.034	Down-regulation
AGC_GRK_BARK_GRK2_ST	P35372	OPRM1	P25098	GRK2	T372	R369C	369	Missense	distal	-3	no	146.811	142.708	EPSD	ICGC;COSMIC	128.034	Down-regulation
AGC_GRK_BARK_GRK2_ST	P35372	OPRM1	P25098	GRK2	T372	R367Q	367	Missense	distal	-5	no	146.811	142.452	EPSD	ICGC;COSMIC	128.034	Down-regulation
AGC_GRK_BARK_GRK2_ST	P35372	OPRM1	P25098	GRK2	T372	R369H	369	Missense	distal	-3	no	146.811	142.206	EPSD	ICGC;COSMIC	128.034	Down-regulation
AGC_GRK_BARK_GRK2_ST	P35372	OPRM1	P25098	GRK2	T372	R367L	367	Missense	distal	-5	no	146.811	132.714	EPSD	ICGC;COSMIC;CCLE	128.034	Down-regulation
AGC_GRK_BARK_GRK2_ST	P35372	OPRM1	P25098	GRK2	T372	R369S	369	Missense	distal	-3	no	146.811	141.065	EPSD	ICGC;COSMIC	128.034	Down-regulation
AGC_GRK_BARK_GRK2_ST	P35372	OPRM1	P25098	GRK2	T372	N371H	371	Missense	proximal	-1	no	146.811	146.677	EPSD	ICGC;COSMIC	128.034	Down-regulation
AGC_GRK_BARK_GRK2_ST	P35372	OPRM1	P25098	GRK2	T372	T372I	372	Missense	central	0	yes	146.811	0.000	EPSD	ICGC;COSMIC	128.034	Loss
AGC_GRK_BARK_GRK2_ST	P35372	OPRM1	P25098	GRK2	T372	R369L	369	Missense	distal	-3	no	146.811	138.761	EPSD	ICGC;COSMIC	128.034	Down-regulation
AGC_GRK_BARK_GRK2_ST	P35372	OPRM1	P25098	GRK2	T372	T378M	378	Missense	distal	6	no	146.811	147.040	EPSD	ICGC;COSMIC	128.034	Up-regulation
AGC_GRK_BARK_GRK2_ST	P35372	OPRM1	P25098	GRK2	T372	H375N	375	Missense	distal	3	no	146.811	144.560	EPSD	ICGC	128.034	Down-regulation
AGC_GRK_BARK_GRK2_ST	P35372	OPRM1	P25098	GRK2	S377	R373T	373	Missense	distal	-4	no	170.730	178.724	PhosphoSitePlus	ICGC;COSMIC	128.034	Up-regulation
AGC_GRK_BARK_GRK2_ST	P35372	OPRM1	P25098	GRK2	S377	N371H	371	Missense	distal	-6	no	170.730	164.525	PhosphoSitePlus	ICGC;COSMIC	128.034	Down-regulation
AGC_GRK_BARK_GRK2_ST	P35372	OPRM1	P25098	GRK2	S377	T372I	372	Missense	distal	-5	no	170.730	156.043	PhosphoSitePlus	ICGC;COSMIC	128.034	Down-regulation
AGC_GRK_BARK_GRK2_ST	P35372	OPRM1	P25098	GRK2	S377	T378M	378	Missense	proximal	1	no	170.730	174.828	PhosphoSitePlus	ICGC;COSMIC	128.034	Up-regulation
AGC_GRK_BARK_GRK2_ST	P35372	OPRM1	P25098	GRK2	S377	H375N	375	Missense	proximal	-2	no	170.730	177.347	PhosphoSitePlus	ICGC	128.034	Up-regulation
AGC_GRK_BARK_GRK2_ST	P35372	OPRM1	P25098	GRK2	T378	R373T	373	Missense	distal	-5	no	163.760	164.381	EPSD	ICGC;COSMIC	128.034	Up-regulation
AGC_GRK_BARK_GRK2_ST	P35372	OPRM1	P25098	GRK2	T378	N371H	371	Missense	distal	-7	no	163.760	157.365	EPSD	ICGC;COSMIC	128.034	Down-regulation
AGC_GRK_BARK_GRK2_ST	P35372	OPRM1	P25098	GRK2	T378	T372I	372	Missense	distal	-6	no	163.760	158.574	EPSD	ICGC;COSMIC	128.034	Down-regulation
AGC_GRK_BARK_GRK2_ST	P35372	OPRM1	P25098	GRK2	T378	T378M	378	Missense	central	0	yes	163.760	0.000	EPSD	ICGC;COSMIC	128.034	Loss
AGC_GRK_BARK_GRK2_ST	P35372	OPRM1	P25098	GRK2	T378	T385S	385	Missense	distal	7	no	163.760	163.949	EPSD	ICGC;COSMIC	128.034	Up-regulation
AGC_GRK_BARK_GRK2_ST	P35372	OPRM1	P25098	GRK2	T378	H375N	375	Missense	distal	-3	no	163.760	172.966	EPSD	ICGC	128.034	Up-regulation
AGC_GRK_BARK_GRK2_ST	P35372	OPRM1	P25098	GRK2	T396	L399R	399	Missense	distal	3	no	158.879	160.827	EPSD	ICGC	128.034	Up-regulation
AGC_GRK_BARK_GRK2_ST	P35372	OPRM1	P25098	GRK2	T396	L392I	392	Missense	distal	-4	no	158.879	142.244	EPSD	ICGC;COSMIC	128.034	Down-regulation
AGC_GRK_BARK_GRK2_ST	P35367	HRH1	P25098	GRK2	S277	Q278K	278	Missense	proximal	1	no	132.643	121.122	EPSD	ICGC	128.034	Loss
AGC_GRK_BARK_GRK2_ST	P35367	HRH1	P25098	GRK2	S396	S396W	396	Missense	central	0	yes	137.287	0.000	EPSD	ICGC;COSMIC	128.034	Loss
AGC_GRK_BARK_GRK2_ST	P35367	HRH1	P25098	GRK2	S396	R393S	393	Missense	distal	-3	no	137.287	131.541	EPSD	ICGC;COSMIC	128.034	Down-regulation
AGC_GRK_BARK_GRK2_ST	P35367	HRH1	P25098	GRK2	S398	S396W	396	Missense	proximal	-2	no	138.286	118.166	PhosphoSitePlus	ICGC;COSMIC	128.034	Loss
AGC_GRK_BARK_GRK2_ST	P35367	HRH1	P25098	GRK2	S398	R393S	393	Missense	distal	-5	no	138.286	133.518	PhosphoSitePlus	ICGC;COSMIC	128.034	Down-regulation
AGC_GRK_BARK_GRK2_ST	P21731	TBXA2R	P25098	GRK2	S239	M244T	244	Missense	distal	5	no	141.033	140.914	PhosphoSitePlus;EPSD	ICGC;COSMIC	128.034	Down-regulation
AGC_GRK_BARK_GRK2_ST	P21731	TBXA2R	P25098	GRK2	S239	S239Y	239	Missense	central	0	yes	141.033	0.000	PhosphoSitePlus;EPSD	ICGC	128.034	Loss
AGC_GRK_BARK_GRK2_ST	P21731	TBXA2R	P25098	GRK2	S239	R237G	237	Missense	proximal	-2	no	141.033	133.871	PhosphoSitePlus;EPSD	ICGC;COSMIC	128.034	Down-regulation
AGC_GRK_BARK_GRK2_ST	P21731	TBXA2R	P25098	GRK2	S239	R235H	235	Missense	distal	-4	no	141.033	132.629	PhosphoSitePlus;EPSD	ICGC;COSMIC	128.034	Down-regulation
AGC_GRK_BARK_GRK2_ST	P21731	TBXA2R	P25098	GRK2	S239	E242K	242	Missense	distal	3	no	141.033	136.233	PhosphoSitePlus;EPSD	ICGC;COSMIC	128.034	Down-regulation
AGC_GRK_BARK_GRK2_ST	P21731	TBXA2R	P25098	GRK2	S324	L319H	319	Missense	distal	-5	no	131.962	134.553	EPSD	ICGC;COSMIC	128.034	Up-regulation
AGC_GRK_BARK_GRK2_ST	P21731	TBXA2R	P25098	GRK2	S324	S331F	331	Missense	distal	7	no	131.962	132.125	EPSD	ICGC	128.034	Up-regulation
AGC_GRK_BARK_GRK2_ST	P21731	TBXA2R	P25098	GRK2	S324	P327S	327	Missense	distal	3	no	131.962	128.964	EPSD	ICGC	128.034	Down-regulation
AGC_GRK_BARK_GRK2_ST	P21731	TBXA2R	P25098	GRK2	S329	Q333K	333	Missense	distal	4	no	136.048	129.186	EPSD	ICGC	128.034	Down-regulation
AGC_GRK_BARK_GRK2_ST	P21731	TBXA2R	P25098	GRK2	S329	S331F	331	Missense	proximal	2	no	136.048	134.555	EPSD	ICGC	128.034	Down-regulation
AGC_GRK_BARK_GRK2_ST	P21731	TBXA2R	P25098	GRK2	S329	P327S	327	Missense	proximal	-2	no	136.048	140.214	EPSD	ICGC	128.034	Up-regulation
AGC_GRK_BARK_GRK2_ST	P21731	TBXA2R	P25098	GRK2	S329	L332F	332	Missense	distal	3	no	136.048	131.763	EPSD	ICGC;COSMIC	128.034	Down-regulation
AGC_GRK_BARK_GRK2_ST	P21731	TBXA2R	P25098	GRK2	S331	T337M	337	Missense	distal	6	no	159.561	159.790	EPSD	ICGC;COSMIC	128.034	Up-regulation
AGC_GRK_BARK_GRK2_ST	P21731	TBXA2R	P25098	GRK2	S331	Q333K	333	Missense	proximal	2	no	159.561	157.124	EPSD	ICGC	128.034	Down-regulation
AGC_GRK_BARK_GRK2_ST	P21731	TBXA2R	P25098	GRK2	S331	S331F	331	Missense	central	0	yes	159.561	0.000	EPSD	ICGC	128.034	Loss
AGC_GRK_BARK_GRK2_ST	P21731	TBXA2R	P25098	GRK2	S331	P327S	327	Missense	distal	-4	no	159.561	169.146	EPSD	ICGC	128.034	Up-regulation
AGC_GRK_BARK_GRK2_ST	P21731	TBXA2R	P25098	GRK2	S331	L332F	332	Missense	proximal	1	no	159.561	155.790	EPSD	ICGC;COSMIC	128.034	Down-regulation
AGC_GRK_BARK_GRK2_ST	O95398	RAPGEF3	P25098	GRK2	S150	H147Y	147	Missense	distal	-3	no	133.869	132.298	EPSD	ICGC	128.034	Down-regulation
AGC_GRK_BARK_GRK2_ST	O95398	RAPGEF3	P25098	GRK2	S370	G374S	374	Missense	distal	4	no	138.681	142.055	EPSD	ICGC;COSMIC	128.034	Up-regulation
AGC_GRK_BARK_GRK2_ST	O95398	RAPGEF3	P25098	GRK2	S370	L366M	366	Missense	distal	-4	no	138.681	132.600	EPSD	ICGC	128.034	Down-regulation
AGC_GRK_BARK_GRK2_ST	O95398	RAPGEF3	P25098	GRK2	T380	R385W	385	Missense	distal	5	no	128.646	122.873	EPSD	ICGC	128.034	Loss
AGC_GRK_BARK_GRK2_ST	O95398	RAPGEF3	P25098	GRK2	T380	G374S	374	Missense	distal	-6	no	128.646	131.552	EPSD	ICGC;COSMIC	128.034	Up-regulation
AGC_GRK_BARK_GRK2_ST	O95398	RAPGEF3	P25098	GRK2	T380	G382D	382	Missense	proximal	2	no	128.646	128.776	EPSD	ICGC;COSMIC;GDSC;CCLE	128.034	Up-regulation
AGC_GRK_BARK_GRK2_ST	O95398	RAPGEF3	P25098	GRK2	T380	R385L	385	Missense	distal	5	no	128.646	124.973	EPSD	ICGC;COSMIC	128.034	Loss
AGC_GRK_BARK_GRK2_ST	P09497	CLTB	P25098	GRK2	T190	Q197K	197	Missense	distal	7	no	137.183	137.351	EPSD	ICGC	128.034	Up-regulation
AGC_GRK_BARK_GRK2_ST	P09497	CLTB	P25098	GRK2	S205	C199G	199	Missense	distal	-6	no	173.206	175.050	PhosphoSitePlus	ICGC;COSMIC	128.034	Up-regulation
AGC_GRK_BARK_GRK2_ST	Q16539	MAPK14	P25098	GRK2	T123	D125Y	125	Missense	proximal	2	no	134.208	133.331	PhosphoSitePlus	ICGC	128.034	Down-regulation
AGC_GRK_BARK_GRK2_ST	Q16539	MAPK14	P25098	GRK2	S326	D321N	321	Missense	distal	-5	no	133.019	127.137	EPSD	ICGC	128.034	Loss
AGC_GRK_BARK_GRK2_ST	P26038	MSN	P25098	GRK2	S90	L93F	93	Missense	distal	3	no	131.598	127.313	EPSD	ICGC;COSMIC	128.034	Loss
AGC_GRK_BARK_GRK2_ST	P26038	MSN	P25098	GRK2	S90	D88N	88	Missense	proximal	-2	no	131.598	126.507	EPSD	ICGC	128.034	Loss
AGC_GRK_BARK_GRK2_ST	P26038	MSN	P25098	GRK2	S90	D88A	88	Missense	proximal	-2	no	131.598	116.064	EPSD	ICGC;COSMIC	128.034	Loss
AGC_GRK_BARK_GRK2_ST	P26038	MSN	P25098	GRK2	S384	R379W	379	Missense	distal	-5	no	139.602	128.268	EPSD	ICGC;COSMIC	128.034	Down-regulation
AGC_GRK_BARK_GRK2_ST	P26038	MSN	P25098	GRK2	S384	Q383H	383	Missense	proximal	-1	no	139.602	143.895	EPSD	ICGC;COSMIC	128.034	Up-regulation
AGC_GRK_BARK_GRK2_ST	P26038	MSN	P25098	GRK2	S384	R379Q	379	Missense	distal	-5	no	139.602	135.243	EPSD	ICGC;COSMIC	128.034	Down-regulation
AGC_GRK_BARK_GRK2_ST	P26038	MSN	P25098	GRK2	S384	K388R	388	Missense	distal	4	no	139.602	146.578	EPSD	ICGC;COSMIC	128.034	Up-regulation
AGC_GRK_BARK_GRK2_ST	P26038	MSN	P25098	GRK2	S384	E385K	385	Missense	proximal	1	no	139.602	122.102	EPSD	ICGC;COSMIC;GDSC;CCLE	128.034	Loss
AGC_GRK_BARK_GRK2_ST	P26038	MSN	P25098	GRK2	T413	L417Q	417	Missense	distal	4	no	124.677	139.457	EPSD	ICGC;COSMIC	128.034	Gain
AGC_GRK_BARK_GRK2_ST	P26038	MSN	P25098	GRK2	T510	R517C	517	Missense	distal	7	no	128.394	128.266	EPSD	ICGC	128.034	Down-regulation
AGC_GRK_BARK_GRK2_ST	P26038	MSN	P25098	GRK2	T510	R517L	517	Missense	distal	7	no	128.394	129.079	EPSD	ICGC	128.034	Up-regulation
AGC_GRK_BARK_GRK2_ST	P26038	MSN	P25098	GRK2	T558	D554N	554	Missense	distal	-4	no	164.331	152.477	PhosphoSitePlus	ICGC;COSMIC	128.034	Down-regulation
AGC_GRK_BARK_GRK2_ST	P26038	MSN	P25098	GRK2	T558	T558I	558	Missense	central	0	yes	164.331	0.000	PhosphoSitePlus	ICGC;COSMIC	128.034	Loss
AGC_GRK_BARK_GRK2_ST	P26038	MSN	P25098	GRK2	T567	F574L	574	Missense	distal	7	no	144.054	144.548	EPSD	ICGC;COSMIC	128.034	Up-regulation
AGC_GRK_BARK_GRK2_ST	P26038	MSN	P25098	GRK2	T567	Q569E	569	Missense	proximal	2	no	144.054	146.310	EPSD	ICGC	128.034	Up-regulation
AGC_GRK_BARK_GRK2_ST	P26038	MSN	P25098	GRK2	S576	F574L	574	Missense	proximal	-2	no	157.522	170.601	EPSD	ICGC;COSMIC	128.034	Up-regulation
AGC_GRK_BARK_GRK2_ST	P26038	MSN	P25098	GRK2	S576	Q569E	569	Missense	distal	-7	no	157.522	160.591	EPSD	ICGC	128.034	Up-regulation
AGC_GRK_BARK_GRK2_ST	Q9Y2W7	KCNIP3	P25098	GRK2	S95	S95F	95	Missense	central	0	yes	135.418	0.000	PhosphoSitePlus	ICGC	128.034	Loss
AGC_GRK_BARK_GRK2_ST	Q9Y2W7	KCNIP3	P25098	GRK2	S95	L96H	96	Missense	proximal	1	no	135.418	143.678	PhosphoSitePlus	ICGC;COSMIC	128.034	Up-regulation
AGC_GRK_BARK_GRK2_ST	Q96A54	ADIPOR1	P25098	GRK2	S7	G12E	12	Missense	distal	5	no	146.400	148.577	EPSD;PhosphoSitePlus	ICGC;COSMIC	128.034	Up-regulation
AGC_GRK_BARK_GRK2_ST	Q96A54	ADIPOR1	P25098	GRK2	S7	S7Y	7	Missense	central	0	yes	146.400	0.000	EPSD;PhosphoSitePlus	ICGC;COSMIC	128.034	Loss
AGC_GRK_BARK_GRK2_ST	Q96A54	ADIPOR1	P25098	GRK2	S7	G14R	14	Missense	distal	7	no	146.400	146.310	EPSD;PhosphoSitePlus	ICGC;COSMIC	128.034	Down-regulation
AGC_GRK_BARK_GRK2_ST	Q96A54	ADIPOR1	P25098	GRK2	T53	P46L	46	Missense	distal	-7	no	143.691	143.907	EPSD;PhosphoSitePlus	ICGC;COSMIC	128.034	Up-regulation
AGC_GRK_BARK_GRK2_ST	Q96A54	ADIPOR1	P25098	GRK2	T53	P55T	55	Missense	proximal	2	no	143.691	140.653	EPSD;PhosphoSitePlus	ICGC;COSMIC	128.034	Down-regulation
AGC_GRK_BARK_GRK2_ST	Q15796	SMAD2	P25098	GRK2	T197	S199C	199	Missense	proximal	2	no	143.095	143.115	PhosphoSitePlus	ICGC;COSMIC	128.034	Up-regulation
AGC_GRK_BARK_GRK2_ST	Q15796	SMAD2	P25098	GRK2	T197	P191Q	191	Missense	distal	-6	no	143.095	152.594	PhosphoSitePlus	ICGC;COSMIC	128.034	Up-regulation
AGC_GRK_BARK_GRK2_ST	P08069	IGF1R	P25098	GRK2	T207	C205Y	205	Missense	proximal	-2	no	125.318	141.379	EPSD	ICGC;COSMIC	128.034	Gain
AGC_GRK_BARK_GRK2_ST	P08069	IGF1R	P25098	GRK2	S609	L602F	602	Missense	distal	-7	no	129.653	125.570	EPSD	ICGC	128.034	Loss
AGC_GRK_BARK_GRK2_ST	P08069	IGF1R	P25098	GRK2	S609	S612F	612	Missense	distal	3	no	129.653	127.809	EPSD	ICGC;COSMIC	128.034	Loss
AGC_GRK_BARK_GRK2_ST	P08069	IGF1R	P25098	GRK2	S1193	V1200I	1200	Missense	distal	7	no	132.846	133.052	EPSD	ICGC;COSMIC	128.034	Up-regulation
AGC_GRK_BARK_GRK2_ST	P08069	IGF1R	P25098	GRK2	S1364	S1364L	1364	Missense	central	0	yes	145.142	0.000	EPSD	ICGC;COSMIC	128.034	Loss
AGC_GRK_BARK_GRK2_ST	P08069	IGF1R	P25098	GRK2	S1365	S1364L	1364	Missense	proximal	-1	no	138.645	128.926	EPSD	ICGC;COSMIC	128.034	Down-regulation
AGC_GRK_BARK_GRK2_ST	P08069	IGF1R	P25098	GRK2	T1366	S1364L	1364	Missense	proximal	-2	no	136.759	128.563	EPSD	ICGC;COSMIC	128.034	Down-regulation
AGC_GRK_BARK_GRK2_ST	O60353	FZD6	P25098	GRK2	S643	A646V	646	Missense	distal	3	no	123.061	129.931	EPSD	ICGC;COSMIC;GDSC;CCLE	128.034	Gain
AGC_GRK_BARK_GRK2_ST	O60353	FZD6	P25098	GRK2	S645	A646V	646	Missense	proximal	1	no	141.936	146.574	EPSD	ICGC;COSMIC;GDSC;CCLE	128.034	Up-regulation
AGC_GRK_BARK_GRK2_ST	O60353	FZD6	P25098	GRK2	S645	V642L	642	Missense	distal	-3	no	141.936	141.251	EPSD	ICGC	128.034	Down-regulation
AGC_GRK_BARK_GRK2_ST	O60353	FZD6	P25098	GRK2	S645	E649Q	649	Missense	distal	4	no	141.936	143.691	EPSD	ICGC;COSMIC	128.034	Up-regulation
AGC_GRK_BARK_GRK2_ST	O60353	FZD6	P25098	GRK2	S648	A646V	646	Missense	proximal	-2	no	131.612	135.768	PhosphoSitePlus	ICGC;COSMIC;GDSC;CCLE	128.034	Up-regulation
AGC_GRK_BARK_GRK2_ST	O60353	FZD6	P25098	GRK2	S648	V642L	642	Missense	distal	-6	no	131.612	123.199	PhosphoSitePlus	ICGC	128.034	Loss
AGC_GRK_BARK_GRK2_ST	O60353	FZD6	P25098	GRK2	S648	E649Q	649	Missense	proximal	1	no	131.612	125.632	PhosphoSitePlus	ICGC;COSMIC	128.034	Loss
AGC_GRK_BARK_GRK2_ST	O60353	FZD6	P25098	GRK2	S673	S666I	666	Missense	distal	-7	no	152.074	157.012	EPSD	ICGC	128.034	Up-regulation
AGC_GRK_BARK_GRK2_ST	O60353	FZD6	P25098	GRK2	S673	L669F	669	Missense	distal	-4	no	152.074	150.255	EPSD	ICGC;COSMIC	128.034	Down-regulation
AGC_GRK_BARK_GRK2_ST	O60353	FZD6	P25098	GRK2	S673	S678I	678	Missense	distal	5	no	152.074	147.561	EPSD	ICGC;COSMIC	128.034	Down-regulation
AGC_GRK_BARK_GRK2_ST	O60353	FZD6	P25098	GRK2	S675	L669F	669	Missense	distal	-6	no	132.040	119.123	EPSD	ICGC;COSMIC	128.034	Loss
AGC_GRK_BARK_GRK2_ST	O60353	FZD6	P25098	GRK2	S675	S678I	678	Missense	distal	3	no	132.040	129.359	EPSD	ICGC;COSMIC	128.034	Down-regulation
AGC_GRK_BARK_GRK2_ST	O60353	FZD6	P25098	GRK2	S678	S678I	678	Missense	central	0	yes	170.997	0.000	EPSD	ICGC;COSMIC	128.034	Loss
AGC_GRK_BARK_GRK2_ST	O60353	FZD6	P25098	GRK2	S679	S678I	678	Missense	proximal	-1	no	161.961	146.643	EPSD	ICGC;COSMIC	128.034	Down-regulation
AGC_GRK_BARK_GRK2_ST	O60353	FZD6	P25098	GRK2	T684	S678I	678	Missense	distal	-6	no	132.339	126.223	EPSD	ICGC;COSMIC	128.034	Loss
AGC_GRK_BARK_GRK2_ST	O60353	FZD6	P25098	GRK2	T684	H689N	689	Missense	distal	5	no	132.339	130.177	EPSD	ICGC;COSMIC	128.034	Down-regulation
AGC_GRK_BARK_GRK2_ST	P37840	SNCA	P25098	GRK2	S129	Q134K	134	Missense	distal	5	no	184.693	182.793	PhosphoSitePlus	ICGC;COSMIC	128.034	Down-regulation
STE_STE11_MEKK2_MAP3K2_ST	P35222	CTNNB1	Q9Y2U5	MAP3K2	S250	L252H	252	Missense	proximal	2	no	2.008	2.200	EPSD	ICGC;COSMIC	2.079	Gain
STE_STE7_MEK1_MAP2K2_ST	P27361	MAPK3	P36507	MAP2K2	T202	T198I	198	Missense	distal	-4	no	11.021	10.986	PhosphoSitePlus;EPSD	ICGC;COSMIC	1.900	Down-regulation
STE_STE7_MEK1_MAP2K2_ST	P05787	KRT8	P36507	MAP2K2	S71	A65T	65	Missense	distal	-6	no	2.947	2.954	EPSD	ICGC	1.900	Up-regulation
STE_STE7_MEK1_MAP2K2_ST	P05787	KRT8	P36507	MAP2K2	T187	R186C	186	Missense	proximal	-1	no	2.105	2.436	EPSD	ICGC;COSMIC	1.900	Up-regulation
STE_STE7_MEK1_MAP2K2_ST	P05787	KRT8	P36507	MAP2K2	T187	E190K	190	Missense	distal	3	no	2.105	2.000	EPSD	ICGC	1.900	Down-regulation
STE_STE7_MEK1_MAP2K2_ST	P05787	KRT8	P36507	MAP2K2	S308	R301W	301	Missense	distal	-7	no	2.602	2.615	EPSD	ICGC;COSMIC	1.900	Up-regulation
STE_STE7_MEK1_MAP2K2_ST	P05787	KRT8	P36507	MAP2K2	S450	A447T	447	Missense	distal	-3	no	1.967	1.976	EPSD	ICGC;CCLE	1.900	Up-regulation
TK_Jak_JAK3_Y	O14939	PLD2	P52333	JAK3	Y296	K292E	292	Missense	distal	-4	no	96.737	96.494	EPSD	ICGC	65.077	Down-regulation
TK_Jak_JAK3_Y	O14939	PLD2	P52333	JAK3	Y296	A299S	299	Missense	distal	3	no	96.737	96.616	EPSD	ICGC;COSMIC	65.077	Down-regulation
TK_Jak_JAK3_Y	O14939	PLD2	P52333	JAK3	Y415	G414D	414	Missense	proximal	-1	no	105.166	104.147	PhosphoSitePlus	ICGC;COSMIC	65.077	Down-regulation
TK_Jak_JAK3_Y	O95644	NFATC1	P52333	JAK3	Y165	E163K	163	Missense	proximal	-2	no	69.614	69.727	EPSD	ICGC;COSMIC	65.077	Up-regulation
TK_Jak_JAK3_Y	O95644	NFATC1	P52333	JAK3	Y165	S158R	158	Missense	distal	-7	no	69.614	61.451	EPSD	ICGC;COSMIC	65.077	Loss
TK_Jak_JAK3_Y	O95644	NFATC1	P52333	JAK3	Y165	L171P	171	Missense	distal	6	no	69.614	69.461	EPSD	ICGC	65.077	Down-regulation
TK_Jak_JAK3_Y	O95644	NFATC1	P52333	JAK3	Y165	D167Y	167	Missense	proximal	2	no	69.614	68.856	EPSD	ICGC;COSMIC	65.077	Down-regulation
TK_Jak_JAK3_Y	O95644	NFATC1	P52333	JAK3	Y268	R273L	273	Missense	distal	5	no	81.913	81.952	EPSD	ICGC;COSMIC	65.077	Up-regulation
TK_Jak_JAK3_Y	O95644	NFATC1	P52333	JAK3	Y268	P262L	262	Missense	distal	-6	no	81.913	81.474	EPSD	ICGC;COSMIC	65.077	Down-regulation
TK_Jak_JAK3_Y	O95644	NFATC1	P52333	JAK3	Y268	G272V	272	Missense	distal	4	no	81.913	74.012	EPSD	ICGC;COSMIC	65.077	Down-regulation
TK_Jak_JAK3_Y	O95644	NFATC1	P52333	JAK3	Y268	P275S	275	Missense	distal	7	no	81.913	82.919	EPSD	ICGC	65.077	Up-regulation
TK_Jak_JAK3_Y	O95644	NFATC1	P52333	JAK3	Y268	R273Q	273	Missense	distal	5	no	81.913	81.941	EPSD	ICGC	65.077	Up-regulation
TK_Jak_JAK3_Y	O95644	NFATC1	P52333	JAK3	Y371	A367V	367	Missense	distal	-4	no	91.322	92.190	PhosphoSitePlus	ICGC;COSMIC	65.077	Up-regulation
TK_Jak_JAK3_Y	O95644	NFATC1	P52333	JAK3	Y371	A364G	364	Missense	distal	-7	no	91.322	75.283	PhosphoSitePlus	ICGC;COSMIC	65.077	Down-regulation
TK_Jak_JAK3_Y	P52333	JAK3	P52333	JAK3	Y506	M511I	511	Missense	distal	5	no	88.067	89.137	EPSD	ICGC;COSMIC;GDSC;CCLE	65.077	Up-regulation
TK_Jak_JAK3_Y	P52333	JAK3	P52333	JAK3	Y506	Q505K	505	Missense	proximal	-1	no	88.067	81.752	EPSD	ICGC;COSMIC	65.077	Down-regulation
TK_Jak_JAK3_Y	P52333	JAK3	P52333	JAK3	Y506	Q501K	501	Missense	distal	-5	no	88.067	86.212	EPSD	ICGC	65.077	Down-regulation
TK_Jak_JAK3_Y	P52333	JAK3	P52333	JAK3	Y785	P791L	791	Missense	distal	6	no	111.759	111.911	PhosphoSitePlus;EPSD	ICGC	65.077	Up-regulation
TK_Jak_JAK3_Y	P52333	JAK3	P52333	JAK3	Y904	R899Q	899	Missense	distal	-5	no	108.604	107.725	EPSD;PhosphoSitePlus	ICGC	65.077	Down-regulation
TK_Jak_JAK3_Y	P52333	JAK3	P52333	JAK3	Y939	S942F	942	Missense	distal	3	no	106.715	100.115	EPSD;PhosphoSitePlus	ICGC;COSMIC	65.077	Down-regulation
TK_Jak_JAK3_Y	P52333	JAK3	P52333	JAK3	Y939	R943H	943	Missense	distal	4	no	106.715	94.317	EPSD;PhosphoSitePlus	ICGC;COSMIC	65.077	Down-regulation
TK_Jak_JAK3_Y	P23458	JAK1	P52333	JAK3	Y993	L994F	994	Missense	proximal	1	no	113.858	109.722	EPSD	ICGC;COSMIC	65.077	Down-regulation
TK_Jak_JAK3_Y	P23458	JAK1	P52333	JAK3	Y993	M991I	991	Missense	proximal	-2	no	113.858	113.469	EPSD	ICGC;COSMIC	65.077	Down-regulation
TK_Jak_JAK3_Y	P23458	JAK1	P52333	JAK3	Y1034	R1041Q	1041	Missense	distal	7	no	121.690	121.789	PhosphoSitePlus;EPSD	ICGC;COSMIC	65.077	Up-regulation
TK_Jak_JAK3_Y	P23458	JAK1	P52333	JAK3	Y1034	V1037I	1037	Missense	distal	3	no	121.690	118.960	PhosphoSitePlus;EPSD	ICGC;COSMIC	65.077	Down-regulation
TK_Jak_JAK3_Y	P23458	JAK1	P52333	JAK3	Y1034	D1031E	1031	Missense	distal	-3	no	121.690	122.228	PhosphoSitePlus;EPSD	ICGC;COSMIC	65.077	Up-regulation
TK_Jak_JAK3_Y	P23458	JAK1	P52333	JAK3	Y1034	Y1034N	1034	Missense	central	0	yes	121.690	0.000	PhosphoSitePlus;EPSD	ICGC;COSMIC	65.077	Loss
TK_Jak_JAK3_Y	P23458	JAK1	P52333	JAK3	Y1035	R1041Q	1041	Missense	distal	6	no	109.428	109.852	EPSD;PhosphoSitePlus	ICGC;COSMIC	65.077	Up-regulation
TK_Jak_JAK3_Y	P23458	JAK1	P52333	JAK3	Y1035	V1037I	1037	Missense	proximal	2	no	109.428	108.761	EPSD;PhosphoSitePlus	ICGC;COSMIC	65.077	Down-regulation
TK_Jak_JAK3_Y	P23458	JAK1	P52333	JAK3	Y1035	D1031E	1031	Missense	distal	-4	no	109.428	109.840	EPSD;PhosphoSitePlus	ICGC;COSMIC	65.077	Up-regulation
TK_Jak_JAK3_Y	P23458	JAK1	P52333	JAK3	Y1035	Y1034N	1034	Missense	proximal	-1	no	109.428	113.342	EPSD;PhosphoSitePlus	ICGC;COSMIC	65.077	Up-regulation
TK_Jak_JAK3_Y	P35222	CTNNB1	P52333	JAK3	Y331	T332N	332	Missense	proximal	1	no	69.894	66.564	EPSD	ICGC;COSMIC	65.077	Down-regulation
TK_Jak_JAK3_Y	Q15717	ELAVL1	P52333	JAK3	Y63	S60R	60	Missense	distal	-3	no	110.612	107.054	PhosphoSitePlus;EPSD	ICGC;COSMIC	65.077	Down-regulation
TK_Jak_JAK3_Y	Q15717	ELAVL1	P52333	JAK3	Y63	N67H	67	Missense	distal	4	no	110.612	93.133	PhosphoSitePlus;EPSD	ICGC;COSMIC	65.077	Down-regulation
TK_Jak_JAK3_Y	Q15717	ELAVL1	P52333	JAK3	Y68	N67H	67	Missense	proximal	-1	no	99.871	92.716	EPSD;PhosphoSitePlus	ICGC;COSMIC	65.077	Down-regulation
TK_Jak_JAK3_Y	Q15717	ELAVL1	P52333	JAK3	Y200	V193M	193	Missense	distal	-7	no	104.116	91.433	EPSD;PhosphoSitePlus	ICGC;CCLE	65.077	Down-regulation
TK_Jak_JAK3_Y	P42224	STAT1	P52333	JAK3	Y701	T704N	704	Missense	distal	3	no	110.959	107.348	PhosphoSitePlus	ICGC;COSMIC	65.077	Down-regulation
TK_Jak_JAK3_Y	P42224	STAT1	P52333	JAK3	Y701	K703E	703	Missense	proximal	2	no	110.959	111.195	PhosphoSitePlus	ICGC	65.077	Up-regulation
TK_Tec_ITK_Y	Q06187	BTK	Q08881	ITK	Y223	M228I	228	Missense	distal	5	no	18.601	18.234	PhosphoSitePlus	ICGC;COSMIC	9.294	Down-regulation
TK_Tec_ITK_Y	Q06187	BTK	Q08881	ITK	Y223	A221D	221	Missense	proximal	-2	no	18.601	16.159	PhosphoSitePlus	ICGC	9.294	Down-regulation
TK_Tec_ITK_Y	Q06187	BTK	Q08881	ITK	Y223	M228T	228	Missense	distal	5	no	18.601	18.558	PhosphoSitePlus	ICGC;COSMIC	9.294	Down-regulation
TK_Tec_ITK_Y	Q06187	BTK	Q08881	ITK	Y225	M228I	228	Missense	distal	3	no	12.025	12.091	EPSD	ICGC;COSMIC	9.294	Up-regulation
TK_Tec_ITK_Y	Q06187	BTK	Q08881	ITK	Y225	A221D	221	Missense	distal	-4	no	12.025	11.391	EPSD	ICGC	9.294	Down-regulation
TK_Tec_ITK_Y	Q06187	BTK	Q08881	ITK	Y225	M228T	228	Missense	distal	3	no	12.025	12.092	EPSD	ICGC;COSMIC	9.294	Up-regulation
TK_Tec_ITK_Y	Q9H4E7	DEF6	Q08881	ITK	Y210	E208K	208	Missense	proximal	-2	no	16.327	15.651	EPSD;PhosphoSitePlus	ICGC;COSMIC	9.294	Down-regulation
TK_Tec_ITK_Y	Q9H4E7	DEF6	Q08881	ITK	Y222	G227W	227	Missense	distal	5	no	19.489	19.801	PhosphoSitePlus;EPSD	ICGC;COSMIC	9.294	Up-regulation
TK_Tec_ITK_Y	P19174	PLCG1	Q08881	ITK	Y93	R100Q	100	Missense	distal	7	no	12.748	12.687	EPSD	ICGC;COSMIC	9.294	Down-regulation
TK_Tec_ITK_Y	P19174	PLCG1	Q08881	ITK	Y775	R778H	778	Missense	distal	3	no	10.668	10.491	EPSD	ICGC;COSMIC	9.294	Down-regulation
TK_Tec_ITK_Y	P19174	PLCG1	Q08881	ITK	Y775	G772E	772	Missense	distal	-3	no	10.668	10.048	EPSD	ICGC	9.294	Down-regulation
TK_Tec_ITK_Y	P19174	PLCG1	Q08881	ITK	Y783	R778H	778	Missense	distal	-5	no	19.117	18.024	PhosphoSitePlus	ICGC;COSMIC	9.294	Down-regulation
TK_Tec_ITK_Y	P19174	PLCG1	Q08881	ITK	Y991	E989Q	989	Missense	proximal	-2	no	9.580	10.989	EPSD	ICGC	9.294	Up-regulation
TK_Tec_ITK_Y	P19174	PLCG1	Q08881	ITK	Y991	P984Q	984	Missense	distal	-7	no	9.580	9.690	EPSD	ICGC;COSMIC	9.294	Up-regulation
TK_Tec_ITK_Y	P51813	BMX	Q08881	ITK	Y216	K221N	221	Missense	distal	5	no	20.962	21.891	PhosphoSitePlus	ICGC;COSMIC	9.294	Up-regulation
TK_Tec_ITK_Y	P51813	BMX	Q08881	ITK	Y216	S212R	212	Missense	distal	-4	no	20.962	20.922	PhosphoSitePlus	ICGC;COSMIC	9.294	Down-regulation
TK_Tec_ITK_Y	Q8TDQ0	HAVCR2	Q08881	ITK	Y265	V271I	271	Missense	distal	6	no	20.501	20.297	PhosphoSitePlus	ICGC;COSMIC	9.294	Down-regulation
TK_Tec_ITK_Y	Q8TDQ0	HAVCR2	Q08881	ITK	Y265	Y265H	265	Missense	central	0	yes	20.501	0.000	PhosphoSitePlus	ICGC	9.294	Loss
TK_Tec_ITK_Y	Q13094	LCP2	Q08881	ITK	Y145	P147L	147	Missense	proximal	2	no	12.142	11.763	EPSD	ICGC;COSMIC	9.294	Down-regulation
TK_Tec_ITK_Y	Q13094	LCP2	Q08881	ITK	Y173	S179P	179	Missense	distal	6	no	18.517	17.960	PhosphoSitePlus	ICGC;COSMIC	9.294	Down-regulation
TK_Tec_ITK_Y	Q13094	LCP2	Q08881	ITK	Y173	P167L	167	Missense	distal	-6	no	18.517	18.058	PhosphoSitePlus	ICGC;COSMIC	9.294	Down-regulation
TK_Tec_ITK_Y	Q13094	LCP2	Q08881	ITK	Y173	D175N	175	Missense	proximal	2	no	18.517	18.501	PhosphoSitePlus	ICGC;COSMIC	9.294	Down-regulation
TK_Tec_ITK_Y	Q13094	LCP2	Q08881	ITK	Y380	G384D	384	Missense	distal	4	no	12.813	12.952	EPSD	ICGC;COSMIC	9.294	Up-regulation
TK_Tec_ITK_Y	Q13094	LCP2	Q08881	ITK	Y423	S425Y	425	Missense	proximal	2	no	16.033	15.930	EPSD	ICGC;COSMIC	9.294	Down-regulation
TK_Tec_ITK_Y	Q13094	LCP2	Q08881	ITK	Y423	R429L	429	Missense	distal	6	no	16.033	16.065	EPSD	ICGC;COSMIC	9.294	Up-regulation
TK_Tec_ITK_Y	Q13094	LCP2	Q08881	ITK	Y423	V424I	424	Missense	proximal	1	no	16.033	16.371	EPSD	ICGC	9.294	Up-regulation
TK_Tec_ITK_Y	Q13094	LCP2	Q08881	ITK	Y426	V424I	424	Missense	proximal	-2	no	8.730	9.331	EPSD	ICGC	9.294	Gain
TK_Csk_CSK_Y	P06239	LCK	P41240	CSK	Y505	E502D	502	Missense	distal	-3	no	101.250	97.694	PhosphoSitePlus	ICGC	33.668	Down-regulation
TK_Csk_CSK_Y	P12931	SRC	P41240	CSK	Y419	G424C	424	Missense	distal	5	no	34.876	34.354	EPSD;PhosphoSitePlus	ICGC;COSMIC	33.668	Down-regulation
TK_Csk_CSK_Y	P12931	SRC	P41240	CSK	Y419	R422W	422	Missense	distal	3	no	34.876	35.174	EPSD;PhosphoSitePlus	ICGC	33.668	Up-regulation
TK_Csk_CSK_Y	P12931	SRC	P41240	CSK	Y530	E534K	534	Missense	distal	4	no	115.622	112.141	PhosphoSitePlus;EPSD	ICGC;COSMIC	33.668	Down-regulation
TK_Csk_CSK_Y	P12931	SRC	P41240	CSK	Y530	E527K	527	Missense	distal	-3	no	115.622	97.073	PhosphoSitePlus;EPSD	ICGC;COSMIC;CCLE	33.668	Down-regulation
TK_Csk_CSK_Y	P07947	YES1	P41240	CSK	Y32	G33A	33	Missense	proximal	1	no	41.419	49.177	EPSD	ICGC;COSMIC	33.668	Up-regulation
TK_Csk_CSK_Y	P07947	YES1	P41240	CSK	Y537	Q536K	536	Missense	proximal	-1	no	109.039	95.844	PhosphoSitePlus	ICGC	33.668	Down-regulation
TK_Csk_CSK_Y	P08631	HCK	P41240	CSK	Y522	Q524K	524	Missense	proximal	2	no	100.465	95.268	EPSD	ICGC;COSMIC	33.668	Down-regulation
TK_Csk_CSK_Y	P08575	PTPRC	P41240	CSK	Y544	Y544C	544	Missense	central	0	yes	44.342	0.000	EPSD	ICGC	33.668	Loss
TK_Csk_CSK_Y	P06241	FYN	P41240	CSK	Y39	P40L	40	Missense	proximal	1	no	56.255	48.508	EPSD	ICGC;COSMIC	33.668	Down-regulation
TK_Csk_CSK_Y	P06241	FYN	P41240	CSK	Y39	P36T	36	Missense	distal	-3	no	56.255	47.631	EPSD	ICGC;COSMIC	33.668	Down-regulation
CMGC_MAPK_ERK5_MAPK7_ST	Q13164	MAPK7	Q13164	MAPK7	T28	K35N	35	Missense	distal	7	no	108.435	107.484	EPSD;PhosphoSitePlus	ICGC	81.800	Down-regulation
CMGC_MAPK_ERK5_MAPK7_ST	Q13164	MAPK7	Q13164	MAPK7	T28	A34S	34	Missense	distal	6	no	108.435	107.714	EPSD;PhosphoSitePlus	ICGC	81.800	Down-regulation
CMGC_MAPK_ERK5_MAPK7_ST	Q13164	MAPK7	Q13164	MAPK7	S210	S210P	210	Missense	central	0	yes	91.311	0.000	EPSD	ICGC	81.800	Loss
CMGC_MAPK_ERK5_MAPK7_ST	Q13164	MAPK7	Q13164	MAPK7	S210	A212T	212	Missense	proximal	2	no	91.311	88.051	EPSD	ICGC;COSMIC	81.800	Down-regulation
CMGC_MAPK_ERK5_MAPK7_ST	Q13164	MAPK7	Q13164	MAPK7	S472	A477D	477	Missense	distal	5	no	93.483	95.752	EPSD	ICGC;COSMIC	81.800	Up-regulation
CMGC_MAPK_ERK5_MAPK7_ST	Q13164	MAPK7	Q13164	MAPK7	S496	A501D	501	Missense	distal	5	no	102.817	105.086	EPSD;PhosphoSitePlus	ICGC;COSMIC	81.800	Up-regulation
CMGC_MAPK_ERK5_MAPK7_ST	Q13164	MAPK7	Q13164	MAPK7	S496	R492K	492	Missense	distal	-4	no	102.817	104.799	EPSD;PhosphoSitePlus	ICGC	81.800	Up-regulation
CMGC_MAPK_ERK5_MAPK7_ST	Q13164	MAPK7	Q13164	MAPK7	S731	D724Y	724	Missense	distal	-7	no	100.755	98.233	PhosphoSitePlus;EPSD	ICGC	81.800	Down-regulation
CMGC_MAPK_ERK5_MAPK7_ST	Q13164	MAPK7	Q13164	MAPK7	T733	A739S	739	Missense	distal	6	no	111.960	111.238	EPSD;PhosphoSitePlus	ICGC	81.800	Down-regulation
CMGC_MAPK_ERK5_MAPK7_ST	Q13164	MAPK7	Q13164	MAPK7	S770	A771S	771	Missense	proximal	1	no	112.602	89.128	EPSD;PhosphoSitePlus	ICGC	81.800	Down-regulation
CMGC_MAPK_ERK5_MAPK7_ST	Q13164	MAPK7	Q13164	MAPK7	S772	A771S	771	Missense	proximal	-1	no	107.012	107.555	EPSD;PhosphoSitePlus	ICGC	81.800	Up-regulation
CMGC_MAPK_ERK5_MAPK7_ST	Q13164	MAPK7	Q13164	MAPK7	S774	A771S	771	Missense	distal	-3	no	119.380	118.741	EPSD;PhosphoSitePlus	ICGC	81.800	Down-regulation
CMGC_MAPK_ERK5_MAPK7_ST	Q13164	MAPK7	Q13164	MAPK7	S776	A771S	771	Missense	distal	-5	no	106.005	104.807	EPSD	ICGC	81.800	Down-regulation
CMGC_MAPK_ERK5_MAPK7_ST	P01100	FOS	Q13164	MAPK7	S32	S26I	26	Missense	distal	-6	no	113.035	109.754	PhosphoSitePlus;EPSD	ICGC	81.800	Down-regulation
CMGC_MAPK_ERK5_MAPK7_ST	P01100	FOS	Q13164	MAPK7	S102	S102P	102	Missense	central	0	yes	91.462	0.000	EPSD	ICGC;COSMIC	81.800	Loss
CMGC_MAPK_ERK5_MAPK7_ST	P01100	FOS	Q13164	MAPK7	S102	A105S	105	Missense	distal	3	no	91.462	92.225	EPSD	ICGC	81.800	Up-regulation
CMGC_MAPK_ERK5_MAPK7_ST	P01100	FOS	Q13164	MAPK7	S102	P95T	95	Missense	distal	-7	no	91.462	92.280	EPSD	ICGC	81.800	Up-regulation
CMGC_MAPK_ERK5_MAPK7_ST	Q02078	MEF2A	Q13164	MAPK7	S98	Y105C	105	Missense	distal	7	no	86.031	83.450	EPSD	ICGC;COSMIC	81.800	Down-regulation
CMGC_MAPK_ERK5_MAPK7_ST	Q02078	MEF2A	Q13164	MAPK7	S98	P99S	99	Missense	proximal	1	no	86.031	57.933	EPSD	ICGC;COSMIC	81.800	Loss
CMGC_MAPK_ERK5_MAPK7_ST	Q02078	MEF2A	Q13164	MAPK7	S98	D102E	102	Missense	distal	4	no	86.031	81.840	EPSD	ICGC;COSMIC	81.800	Down-regulation
CMGC_MAPK_ERK5_MAPK7_ST	Q02078	MEF2A	Q13164	MAPK7	S98	D97N	97	Missense	proximal	-1	no	86.031	85.755	EPSD	ICGC	81.800	Down-regulation
CMGC_MAPK_ERK5_MAPK7_ST	Q02078	MEF2A	Q13164	MAPK7	S192	P196F	196	Missense	distal	4	no	94.229	76.179	EPSD	ICGC	81.800	Loss
CMGC_MAPK_ERK5_MAPK7_ST	Q02078	MEF2A	Q13164	MAPK7	S192	P196L	196	Missense	distal	4	no	94.229	93.179	EPSD	ICGC	81.800	Down-regulation
CMGC_MAPK_ERK5_MAPK7_ST	Q02078	MEF2A	Q13164	MAPK7	S289	K282N	282	Missense	distal	-7	no	88.758	88.591	EPSD	ICGC;COSMIC	81.800	Down-regulation
CMGC_MAPK_ERK5_MAPK7_ST	Q02078	MEF2A	Q13164	MAPK7	S417	Q422P	422	Missense	distal	5	no	83.999	82.027	EPSD	ICGC;COSMIC	81.800	Down-regulation
CMGC_MAPK_ERK5_MAPK7_ST	Q02078	MEF2A	Q13164	MAPK7	S417	Q421P	421	Missense	distal	4	no	83.999	87.163	EPSD	ICGC;COSMIC	81.800	Up-regulation
CMGC_MAPK_ERK5_MAPK7_ST	Q12959	DLG1	Q13164	MAPK7	S70	E74K	74	Missense	distal	4	no	85.119	101.113	EPSD	ICGC;COSMIC	81.800	Up-regulation
CMGC_MAPK_ERK5_MAPK7_ST	Q12959	DLG1	Q13164	MAPK7	S86	L87I	87	Missense	proximal	1	no	89.177	55.119	EPSD	ICGC	81.800	Loss
CMGC_MAPK_ERK5_MAPK7_ST	Q12959	DLG1	Q13164	MAPK7	S86	S90P	90	Missense	distal	4	no	89.177	85.522	EPSD	ICGC;COSMIC	81.800	Down-regulation
CMGC_MAPK_ERK5_MAPK7_ST	Q12959	DLG1	Q13164	MAPK7	S100	L101I	101	Missense	proximal	1	no	93.013	58.955	EPSD	ICGC;COSMIC	81.800	Loss
CMGC_MAPK_ERK5_MAPK7_ST	Q12959	DLG1	Q13164	MAPK7	S100	S102R	102	Missense	proximal	2	no	93.013	86.843	EPSD	ICGC	81.800	Down-regulation
CMGC_MAPK_ERK5_MAPK7_ST	Q12959	DLG1	Q13164	MAPK7	S102	L101I	101	Missense	proximal	-1	no	90.047	90.414	EPSD	ICGC;COSMIC	81.800	Up-regulation
CMGC_MAPK_ERK5_MAPK7_ST	Q12959	DLG1	Q13164	MAPK7	S102	S102R	102	Missense	central	0	yes	90.047	0.000	EPSD	ICGC	81.800	Loss
CMGC_MAPK_ERK5_MAPK7_ST	Q12959	DLG1	Q13164	MAPK7	S102	R109M	109	Missense	distal	7	no	90.047	91.318	EPSD	ICGC;COSMIC	81.800	Up-regulation
CMGC_MAPK_ERK5_MAPK7_ST	Q12959	DLG1	Q13164	MAPK7	S122	P116T	116	Missense	distal	-6	no	94.597	94.290	EPSD	ICGC	81.800	Down-regulation
CMGC_MAPK_ERK5_MAPK7_ST	Q12959	DLG1	Q13164	MAPK7	S158	T163K	163	Missense	distal	5	no	107.598	108.281	PhosphoSitePlus	ICGC	81.800	Up-regulation
CMGC_MAPK_ERK5_MAPK7_ST	Q12959	DLG1	Q13164	MAPK7	S579	Y585H	585	Missense	distal	6	no	88.990	92.196	EPSD	ICGC;COSMIC	81.800	Up-regulation
CMGC_MAPK_ERK5_MAPK7_ST	Q13163	MAP2K5	Q13164	MAPK7	S129	P128T	128	Missense	proximal	-1	no	105.888	106.102	EPSD;PhosphoSitePlus	ICGC;COSMIC	81.800	Up-regulation
CMGC_MAPK_ERK5_MAPK7_ST	Q13163	MAP2K5	Q13164	MAPK7	S129	A135S	135	Missense	distal	6	no	105.888	105.166	EPSD;PhosphoSitePlus	ICGC	81.800	Down-regulation
CMGC_MAPK_ERK5_MAPK7_ST	Q13163	MAP2K5	Q13164	MAPK7	S137	S142I	142	Missense	distal	5	no	110.596	109.549	EPSD;PhosphoSitePlus	ICGC;COSMIC	81.800	Down-regulation
CMGC_MAPK_ERK5_MAPK7_ST	Q13163	MAP2K5	Q13164	MAPK7	S137	A135S	135	Missense	proximal	-2	no	110.596	111.396	EPSD;PhosphoSitePlus	ICGC	81.800	Up-regulation
CMGC_MAPK_ERK5_MAPK7_ST	Q13163	MAP2K5	Q13164	MAPK7	S142	S142I	142	Missense	central	0	yes	107.084	0.000	PhosphoSitePlus;EPSD	ICGC;COSMIC	81.800	Loss
CMGC_MAPK_ERK5_MAPK7_ST	Q13163	MAP2K5	Q13164	MAPK7	S142	A135S	135	Missense	distal	-7	no	107.084	106.822	PhosphoSitePlus;EPSD	ICGC	81.800	Down-regulation
CMGC_MAPK_ERK5_MAPK7_ST	Q13163	MAP2K5	Q13164	MAPK7	S144	S142I	142	Missense	proximal	-2	no	86.749	82.680	EPSD	ICGC;COSMIC	81.800	Down-regulation
CMGC_MAPK_ERK5_MAPK7_ST	Q13163	MAP2K5	Q13164	MAPK7	S144	A150V	150	Missense	distal	6	no	86.749	84.283	EPSD	ICGC;COSMIC	81.800	Down-regulation
CMGC_MAPK_ERK5_MAPK7_ST	Q13163	MAP2K5	Q13164	MAPK7	S149	S142I	142	Missense	distal	-7	no	106.873	106.515	EPSD;PhosphoSitePlus	ICGC;COSMIC	81.800	Down-regulation
CMGC_MAPK_ERK5_MAPK7_ST	Q13163	MAP2K5	Q13164	MAPK7	S149	A150V	150	Missense	proximal	1	no	106.873	29.460	EPSD;PhosphoSitePlus	ICGC;COSMIC	81.800	Loss
CMGC_MAPK_ERK5_MAPK7_ST	Q06413	MEF2C	Q13164	MAPK7	S59	T60N	60	Missense	proximal	1	no	36.523	89.984	EPSD	ICGC	81.800	Gain
CMGC_MAPK_ERK5_MAPK7_ST	Q06413	MEF2C	Q13164	MAPK7	T80	E86K	86	Missense	distal	6	no	89.534	87.939	EPSD	ICGC;COSMIC	81.800	Down-regulation
CMGC_MAPK_ERK5_MAPK7_ST	Q06413	MEF2C	Q13164	MAPK7	T80	V85E	85	Missense	distal	5	no	89.534	91.995	EPSD	ICGC;COSMIC	81.800	Up-regulation
CMGC_MAPK_ERK5_MAPK7_ST	Q06413	MEF2C	Q13164	MAPK7	T80	H76N	76	Missense	distal	-4	no	89.534	90.299	EPSD	ICGC;COSMIC	81.800	Up-regulation
CMGC_MAPK_ERK5_MAPK7_ST	Q06413	MEF2C	Q13164	MAPK7	T80	T80K	80	Missense	central	0	yes	89.534	0.000	EPSD	ICGC	81.800	Loss
CMGC_MAPK_ERK5_MAPK7_ST	Q06413	MEF2C	Q13164	MAPK7	T80	D83V	83	Missense	distal	3	no	89.534	87.650	EPSD	ICGC	81.800	Down-regulation
CMGC_MAPK_ERK5_MAPK7_ST	Q06413	MEF2C	Q13164	MAPK7	T80	E77V	77	Missense	distal	-3	no	89.534	83.815	EPSD	ICGC;COSMIC	81.800	Down-regulation
CMGC_MAPK_ERK5_MAPK7_ST	Q06413	MEF2C	Q13164	MAPK7	S82	E86K	86	Missense	distal	4	no	71.665	87.659	EPSD	ICGC;COSMIC	81.800	Gain
CMGC_MAPK_ERK5_MAPK7_ST	Q06413	MEF2C	Q13164	MAPK7	S98	D105N	105	Missense	distal	7	no	96.927	95.539	EPSD	ICGC;COSMIC	81.800	Down-regulation
CMGC_MAPK_ERK5_MAPK7_ST	Q06413	MEF2C	Q13164	MAPK7	S98	D104E	104	Missense	distal	6	no	96.927	96.205	EPSD	ICGC;COSMIC	81.800	Down-regulation
CMGC_MAPK_ERK5_MAPK7_ST	Q06413	MEF2C	Q13164	MAPK7	S110	D105N	105	Missense	distal	-5	no	95.125	90.137	EPSD	ICGC;COSMIC	81.800	Down-regulation
CMGC_MAPK_ERK5_MAPK7_ST	Q06413	MEF2C	Q13164	MAPK7	S110	G108C	108	Missense	proximal	-2	no	95.125	88.890	EPSD	ICGC;COSMIC	81.800	Down-regulation
CMGC_MAPK_ERK5_MAPK7_ST	Q06413	MEF2C	Q13164	MAPK7	S110	D104E	104	Missense	distal	-6	no	95.125	97.983	EPSD	ICGC;COSMIC	81.800	Up-regulation
CMGC_MAPK_ERK5_MAPK7_ST	Q06413	MEF2C	Q13164	MAPK7	S110	Y117H	117	Missense	distal	7	no	95.125	95.634	EPSD	ICGC	81.800	Up-regulation
CMGC_MAPK_ERK5_MAPK7_ST	Q06413	MEF2C	Q13164	MAPK7	S110	S110I	110	Missense	central	0	yes	95.125	0.000	EPSD	ICGC;COSMIC	81.800	Loss
CMGC_MAPK_ERK5_MAPK7_ST	Q06413	MEF2C	Q13164	MAPK7	S228	G230S	230	Missense	proximal	2	no	82.715	86.674	EPSD	ICGC;COSMIC	81.800	Up-regulation
CMGC_MAPK_ERK5_MAPK7_ST	Q06413	MEF2C	Q13164	MAPK7	S228	V227A	227	Missense	proximal	-1	no	82.715	81.637	EPSD	ICGC;COSMIC	81.800	Loss
CMGC_MAPK_ERK5_MAPK7_ST	Q06413	MEF2C	Q13164	MAPK7	T293	A288S	288	Missense	distal	-5	no	94.140	92.943	EPSD	ICGC;COSMIC	81.800	Down-regulation
CMGC_MAPK_ERK5_MAPK7_ST	Q06413	MEF2C	Q13164	MAPK7	T293	S297F	297	Missense	distal	4	no	94.140	72.435	EPSD	ICGC;COSMIC	81.800	Loss
CMGC_MAPK_ERK5_MAPK7_ST	Q06413	MEF2C	Q13164	MAPK7	T300	S297F	297	Missense	distal	-3	no	92.300	91.891	EPSD	ICGC;COSMIC	81.800	Down-regulation
CMGC_MAPK_ERK5_MAPK7_ST	Q06413	MEF2C	Q13164	MAPK7	S387	L380F	380	Missense	distal	-7	no	104.408	103.281	PhosphoSitePlus	ICGC;COSMIC	81.800	Down-regulation
CMGC_MAPK_ERK5_MAPK7_ST	Q06413	MEF2C	Q13164	MAPK7	S396	P397R	397	Missense	proximal	1	no	83.625	19.545	EPSD	ICGC;COSMIC	81.800	Loss
CMGC_MAPK_ERK5_MAPK7_ST	Q06413	MEF2C	Q13164	MAPK7	S396	P397T	397	Missense	proximal	1	no	83.625	19.444	EPSD	ICGC;COSMIC	81.800	Loss
CMGC_MAPK_ERK5_MAPK7_ST	Q06413	MEF2C	Q13164	MAPK7	T404	P397R	397	Missense	distal	-7	no	82.621	81.961	EPSD	ICGC;COSMIC	81.800	Down-regulation
CMGC_MAPK_ERK5_MAPK7_ST	Q06413	MEF2C	Q13164	MAPK7	T404	T404M	404	Missense	central	0	yes	82.621	0.000	EPSD	ICGC;COSMIC	81.800	Loss
CMGC_MAPK_ERK5_MAPK7_ST	Q06413	MEF2C	Q13164	MAPK7	T404	T404K	404	Missense	central	0	yes	82.621	0.000	EPSD	ICGC	81.800	Loss
CMGC_MAPK_ERK5_MAPK7_ST	Q06413	MEF2C	Q13164	MAPK7	T404	P397T	397	Missense	distal	-7	no	82.621	83.439	EPSD	ICGC;COSMIC	81.800	Up-regulation
CMGC_MAPK_ERK5_MAPK7_ST	Q06413	MEF2C	Q13164	MAPK7	S419	S426R	426	Missense	distal	7	no	111.494	109.057	EPSD	ICGC	81.800	Down-regulation
CMGC_MAPK_ERK5_MAPK7_ST	P29590	PML	Q13164	MAPK7	S399	V398L	398	Missense	proximal	-1	no	84.948	84.475	EPSD	ICGC	81.800	Down-regulation
CMGC_MAPK_ERK5_MAPK7_ST	P29590	PML	Q13164	MAPK7	S403	P410A	410	Missense	distal	7	no	108.190	108.633	EPSD;PhosphoSitePlus	ICGC;COSMIC	81.800	Up-regulation
CMGC_MAPK_ERK5_MAPK7_ST	P29590	PML	Q13164	MAPK7	S403	V398L	398	Missense	distal	-5	no	108.190	109.320	EPSD;PhosphoSitePlus	ICGC	81.800	Up-regulation
CMGC_MAPK_ERK5_MAPK7_ST	P29590	PML	Q13164	MAPK7	S403	A407S	407	Missense	distal	4	no	108.190	113.717	EPSD;PhosphoSitePlus	ICGC;COSMIC	81.800	Up-regulation
CMGC_MAPK_ERK5_MAPK7_ST	P29590	PML	Q13164	MAPK7	S403	A407T	407	Missense	distal	4	no	108.190	90.363	EPSD;PhosphoSitePlus	ICGC;COSMIC	81.800	Down-regulation
CMGC_MAPK_ERK5_MAPK7_ST	P29590	PML	Q13164	MAPK7	T409	P410A	410	Missense	proximal	1	no	107.565	102.941	PhosphoSitePlus;EPSD	ICGC;COSMIC	81.800	Down-regulation
CMGC_MAPK_ERK5_MAPK7_ST	P29590	PML	Q13164	MAPK7	T409	A407S	407	Missense	proximal	-2	no	107.565	108.364	PhosphoSitePlus;EPSD	ICGC;COSMIC	81.800	Up-regulation
CMGC_MAPK_ERK5_MAPK7_ST	P29590	PML	Q13164	MAPK7	T409	A407T	407	Missense	proximal	-2	no	107.565	105.974	PhosphoSitePlus;EPSD	ICGC;COSMIC	81.800	Down-regulation
CMGC_MAPK_ERK5_MAPK7_ST	P29590	PML	Q13164	MAPK7	S505	Q508H	508	Missense	distal	3	no	92.499	92.341	EPSD	ICGC	81.800	Down-regulation
CMGC_MAPK_ERK5_MAPK7_ST	P29590	PML	Q13164	MAPK7	S505	S505F	505	Missense	central	0	yes	92.499	0.000	EPSD	ICGC	81.800	Loss
CMGC_MAPK_ERK5_MAPK7_ST	P29590	PML	Q13164	MAPK7	S514	Q508H	508	Missense	distal	-6	no	82.293	83.524	EPSD	ICGC	81.800	Up-regulation
CMGC_MAPK_ERK5_MAPK7_ST	P29590	PML	Q13164	MAPK7	S518	P525L	525	Missense	distal	7	no	91.672	91.080	EPSD	ICGC;COSMIC;GDSC;CCLE	81.800	Down-regulation
CMGC_MAPK_ERK5_MAPK7_ST	P29590	PML	Q13164	MAPK7	S527	P525L	525	Missense	proximal	-2	no	92.006	89.261	EPSD	ICGC;COSMIC;GDSC;CCLE	81.800	Down-regulation
CMGC_MAPK_ERK5_MAPK7_ST	P29590	PML	Q13164	MAPK7	S527	P526L	526	Missense	proximal	-1	no	92.006	92.249	EPSD	ICGC	81.800	Up-regulation
CMGC_MAPK_ERK5_MAPK7_ST	P29590	PML	Q13164	MAPK7	S530	P525L	525	Missense	distal	-5	no	93.594	94.895	EPSD	ICGC;COSMIC;GDSC;CCLE	81.800	Up-regulation
CMGC_MAPK_ERK5_MAPK7_ST	P29590	PML	Q13164	MAPK7	S530	S535L	535	Missense	distal	5	no	93.594	91.475	EPSD	ICGC;COSMIC	81.800	Down-regulation
CMGC_MAPK_ERK5_MAPK7_ST	P29590	PML	Q13164	MAPK7	S530	P526L	526	Missense	distal	-4	no	93.594	96.271	EPSD	ICGC	81.800	Up-regulation
CMGC_MAPK_ERK5_MAPK7_ST	P29590	PML	Q13164	MAPK7	S542	A549V	549	Missense	distal	7	no	83.652	82.066	EPSD	ICGC;COSMIC	81.800	Down-regulation
CMGC_MAPK_ERK5_MAPK7_ST	P29590	PML	Q13164	MAPK7	S542	S535L	535	Missense	distal	-7	no	83.652	84.118	EPSD	ICGC;COSMIC	81.800	Up-regulation
CMGC_MAPK_ERK5_MAPK7_ST	P29590	PML	Q13164	MAPK7	S578	S579I	579	Missense	proximal	1	no	96.073	71.655	EPSD	ICGC;COSMIC	81.800	Loss
CMGC_MAPK_ERK5_MAPK7_ST	P29590	PML	Q13164	MAPK7	S578	S571F	571	Missense	distal	-7	no	96.073	95.413	EPSD	ICGC	81.800	Down-regulation
CMGC_MAPK_ERK5_MAPK7_ST	P29590	PML	Q13164	MAPK7	S579	Q586H	586	Missense	distal	7	no	86.463	86.713	EPSD	ICGC	81.800	Up-regulation
CMGC_MAPK_ERK5_MAPK7_ST	P29590	PML	Q13164	MAPK7	S579	S579I	579	Missense	central	0	yes	86.463	0.000	EPSD	ICGC;COSMIC	81.800	Loss
CMGC_MAPK_ERK5_MAPK7_ST	P29590	PML	Q13164	MAPK7	S580	Q586H	586	Missense	distal	6	no	87.629	85.103	EPSD	ICGC	81.800	Down-regulation
CMGC_MAPK_ERK5_MAPK7_ST	P29590	PML	Q13164	MAPK7	S580	S579I	579	Missense	proximal	-1	no	87.629	88.058	EPSD	ICGC;COSMIC	81.800	Up-regulation
CMGC_MAPK_ERK5_MAPK7_ST	P29590	PML	Q13164	MAPK7	T592	L593P	593	Missense	proximal	1	no	85.995	104.452	EPSD	ICGC	81.800	Up-regulation
CMGC_MAPK_ERK5_MAPK7_ST	P29590	PML	Q13164	MAPK7	T592	Q586H	586	Missense	distal	-6	no	85.995	87.225	EPSD	ICGC	81.800	Up-regulation
CMGC_MAPK_ERK5_MAPK7_ST	P29590	PML	Q13164	MAPK7	T592	S591C	591	Missense	proximal	-1	no	85.995	86.864	EPSD	ICGC;COSMIC	81.800	Up-regulation
CMGC_MAPK_ERK5_MAPK7_ST	P29590	PML	Q13164	MAPK7	T592	L596F	596	Missense	distal	4	no	85.995	68.995	EPSD	ICGC;COSMIC	81.800	Loss
CMGC_MAPK_ERK5_MAPK7_ST	O00141	SGK1	Q13164	MAPK7	S74	P79A	79	Missense	distal	5	no	91.525	91.603	EPSD	ICGC;COSMIC	81.800	Up-regulation
CMGC_MAPK_ERK5_MAPK7_ST	O00141	SGK1	Q13164	MAPK7	S74	L68V	68	Missense	distal	-6	no	91.525	86.960	EPSD	ICGC;COSMIC;CCLE	81.800	Down-regulation
CMGC_MAPK_ERK5_MAPK7_ST	O00141	SGK1	Q13164	MAPK7	S74	P75T	75	Missense	proximal	1	no	91.525	27.345	EPSD	ICGC;COSMIC	81.800	Loss
CMGC_MAPK_ERK5_MAPK7_ST	O00141	SGK1	Q13164	MAPK7	S74	A71P	71	Missense	distal	-3	no	91.525	93.538	EPSD	ICGC	81.800	Up-regulation
CMGC_MAPK_ERK5_MAPK7_ST	O00141	SGK1	Q13164	MAPK7	S74	A71V	71	Missense	distal	-3	no	91.525	86.074	EPSD	ICGC;COSMIC	81.800	Down-regulation
CMGC_MAPK_ERK5_MAPK7_ST	O00141	SGK1	Q13164	MAPK7	S74	A71D	71	Missense	distal	-3	no	91.525	92.172	EPSD	ICGC	81.800	Up-regulation
CMGC_MAPK_ERK5_MAPK7_ST	O00141	SGK1	Q13164	MAPK7	S74	P73T	73	Missense	proximal	-1	no	91.525	91.740	EPSD	ICGC	81.800	Up-regulation
CMGC_MAPK_ERK5_MAPK7_ST	O00141	SGK1	Q13164	MAPK7	S74	P76Q	76	Missense	proximal	2	no	91.525	97.840	EPSD	ICGC	81.800	Up-regulation
CMGC_MAPK_ERK5_MAPK7_ST	O00141	SGK1	Q13164	MAPK7	S74	M69V	69	Missense	distal	-5	no	91.525	90.973	EPSD	ICGC;COSMIC	81.800	Down-regulation
CMGC_MAPK_ERK5_MAPK7_ST	O00141	SGK1	Q13164	MAPK7	S74	P73S	73	Missense	proximal	-1	no	91.525	91.706	EPSD	ICGC;COSMIC	81.800	Up-regulation
CMGC_MAPK_ERK5_MAPK7_ST	O00141	SGK1	Q13164	MAPK7	S74	P77S	77	Missense	distal	3	no	91.525	91.085	EPSD	ICGC;COSMIC	81.800	Down-regulation
CMGC_MAPK_ERK5_MAPK7_ST	O00141	SGK1	Q13164	MAPK7	S74	P79L	79	Missense	distal	5	no	91.525	90.299	EPSD	ICGC;CCLE	81.800	Down-regulation
CMGC_MAPK_ERK5_MAPK7_ST	O00141	SGK1	Q13164	MAPK7	S74	E67D	67	Missense	distal	-7	no	91.525	90.787	EPSD	ICGC	81.800	Down-regulation
CMGC_MAPK_ERK5_MAPK7_ST	O00141	SGK1	Q13164	MAPK7	S74	S74Y	74	Missense	central	0	yes	91.525	0.000	EPSD	ICGC	81.800	Loss
CMGC_MAPK_ERK5_MAPK7_ST	O00141	SGK1	Q13164	MAPK7	S74	M69L	69	Missense	distal	-5	no	91.525	92.102	EPSD	ICGC;COSMIC	81.800	Up-regulation
CMGC_MAPK_ERK5_MAPK7_ST	O00141	SGK1	Q13164	MAPK7	S78	P79A	79	Missense	proximal	1	no	107.871	103.247	PhosphoSitePlus	ICGC;COSMIC	81.800	Down-regulation
CMGC_MAPK_ERK5_MAPK7_ST	O00141	SGK1	Q13164	MAPK7	S78	P75T	75	Missense	distal	-3	no	107.871	104.650	PhosphoSitePlus	ICGC;COSMIC	81.800	Down-regulation
CMGC_MAPK_ERK5_MAPK7_ST	O00141	SGK1	Q13164	MAPK7	S78	A71P	71	Missense	distal	-7	no	107.871	107.454	PhosphoSitePlus	ICGC	81.800	Down-regulation
CMGC_MAPK_ERK5_MAPK7_ST	O00141	SGK1	Q13164	MAPK7	S78	A71V	71	Missense	distal	-7	no	107.871	107.021	PhosphoSitePlus	ICGC;COSMIC	81.800	Down-regulation
CMGC_MAPK_ERK5_MAPK7_ST	O00141	SGK1	Q13164	MAPK7	S78	A71D	71	Missense	distal	-7	no	107.871	108.460	PhosphoSitePlus	ICGC	81.800	Up-regulation
CMGC_MAPK_ERK5_MAPK7_ST	O00141	SGK1	Q13164	MAPK7	S78	P73T	73	Missense	distal	-5	no	107.871	108.580	PhosphoSitePlus	ICGC	81.800	Up-regulation
CMGC_MAPK_ERK5_MAPK7_ST	O00141	SGK1	Q13164	MAPK7	S78	P76Q	76	Missense	proximal	-2	no	107.871	108.243	PhosphoSitePlus	ICGC	81.800	Up-regulation
CMGC_MAPK_ERK5_MAPK7_ST	O00141	SGK1	Q13164	MAPK7	S78	P73S	73	Missense	distal	-5	no	107.871	108.273	PhosphoSitePlus	ICGC;COSMIC	81.800	Up-regulation
CMGC_MAPK_ERK5_MAPK7_ST	O00141	SGK1	Q13164	MAPK7	S78	P77S	77	Missense	proximal	-1	no	107.871	108.052	PhosphoSitePlus	ICGC;COSMIC	81.800	Up-regulation
CMGC_MAPK_ERK5_MAPK7_ST	O00141	SGK1	Q13164	MAPK7	S78	P79L	79	Missense	proximal	1	no	107.871	89.414	PhosphoSitePlus	ICGC;CCLE	81.800	Down-regulation
CMGC_MAPK_ERK5_MAPK7_ST	O00141	SGK1	Q13164	MAPK7	S78	S74Y	74	Missense	distal	-4	no	107.871	107.424	PhosphoSitePlus	ICGC	81.800	Down-regulation
CMGC_MAPK_ERK5_MAPK7_ST	O00141	SGK1	Q13164	MAPK7	S377	R383Q	383	Missense	distal	6	no	85.464	91.468	EPSD	ICGC;COSMIC	81.800	Up-regulation
CMGC_MAPK_ERK5_MAPK7_ST	O00141	SGK1	Q13164	MAPK7	S377	N380I	380	Missense	distal	3	no	85.464	87.400	EPSD	ICGC;COSMIC	81.800	Up-regulation
CMGC_MAPK_ERK5_MAPK7_ST	O00141	SGK1	Q13164	MAPK7	S377	P379T	379	Missense	proximal	2	no	85.464	85.290	EPSD	ICGC;COSMIC	81.800	Down-regulation
CMGC_MAPK_ERK5_MAPK7_ST	P14921	ETS1	Q13164	MAPK7	S26	P25L	25	Missense	proximal	-1	no	95.703	95.946	EPSD	ICGC;COSMIC	81.800	Up-regulation
CMGC_MAPK_ERK5_MAPK7_ST	P14921	ETS1	Q13164	MAPK7	S26	E22D	22	Missense	distal	-4	no	95.703	97.441	EPSD	ICGC;COSMIC	81.800	Up-regulation
CMGC_MAPK_ERK5_MAPK7_ST	P14921	ETS1	Q13164	MAPK7	S26	D28N	28	Missense	proximal	2	no	95.703	93.095	EPSD	ICGC;COSMIC	81.800	Down-regulation
CMGC_MAPK_ERK5_MAPK7_ST	P14921	ETS1	Q13164	MAPK7	S26	D20N	20	Missense	distal	-6	no	95.703	102.675	EPSD	ICGC;COSMIC	81.800	Up-regulation
CMGC_DYRK_HIPK_HIPK2_ST	Q9P1Z0	ZBTB4	Q9H2X6	HIPK2	S90	S95F	95	Missense	distal	5	no	101.860	101.991	EPSD	ICGC	98.777	Up-regulation
CMGC_DYRK_HIPK_HIPK2_ST	Q9P1Z0	ZBTB4	Q9H2X6	HIPK2	S91	S95F	95	Missense	distal	4	no	100.976	94.899	EPSD	ICGC	98.777	Loss
CMGC_DYRK_HIPK_HIPK2_ST	Q9P1Z0	ZBTB4	Q9H2X6	HIPK2	S92	S95F	95	Missense	distal	3	no	101.620	100.871	EPSD	ICGC	98.777	Down-regulation
CMGC_DYRK_HIPK_HIPK2_ST	Q9P1Z0	ZBTB4	Q9H2X6	HIPK2	S93	S95F	95	Missense	proximal	2	no	99.614	96.723	EPSD	ICGC	98.777	Loss
CMGC_DYRK_HIPK_HIPK2_ST	Q9P1Z0	ZBTB4	Q9H2X6	HIPK2	S104	S103C	103	Missense	proximal	-1	no	103.114	99.717	EPSD	ICGC	98.777	Down-regulation
CMGC_DYRK_HIPK_HIPK2_ST	Q9P1Z0	ZBTB4	Q9H2X6	HIPK2	S535	P542T	542	Missense	distal	7	no	103.313	103.314	EPSD	ICGC	98.777	Up-regulation
CMGC_DYRK_HIPK_HIPK2_ST	Q9P1Z0	ZBTB4	Q9H2X6	HIPK2	S541	P542T	542	Missense	proximal	1	no	112.412	-38.923	EPSD	ICGC	98.777	Loss
CMGC_DYRK_HIPK_HIPK2_ST	Q9P1Z0	ZBTB4	Q9H2X6	HIPK2	S629	S636R	636	Missense	distal	7	no	114.140	113.535	EPSD	ICGC	98.777	Down-regulation
CMGC_DYRK_HIPK_HIPK2_ST	Q9P1Z0	ZBTB4	Q9H2X6	HIPK2	S636	S636R	636	Missense	central	0	yes	102.742	0.000	EPSD	ICGC	98.777	Loss
CMGC_DYRK_HIPK_HIPK2_ST	Q9P1Z0	ZBTB4	Q9H2X6	HIPK2	T710	E714K	714	Missense	distal	4	no	114.402	114.880	EPSD	ICGC	98.777	Up-regulation
CMGC_DYRK_HIPK_HIPK2_ST	Q9P1Z0	ZBTB4	Q9H2X6	HIPK2	T710	R704W	704	Missense	distal	-6	no	114.402	113.942	EPSD	ICGC	98.777	Down-regulation
CMGC_DYRK_HIPK_HIPK2_ST	Q9P1Z0	ZBTB4	Q9H2X6	HIPK2	T710	A712V	712	Missense	proximal	2	no	114.402	112.810	EPSD	ICGC;COSMIC;GDSC	98.777	Down-regulation
CMGC_DYRK_HIPK_HIPK2_ST	Q9P1Z0	ZBTB4	Q9H2X6	HIPK2	T795	G793W	793	Missense	proximal	-2	no	114.414	113.263	EPSD;PhosphoSitePlus	ICGC;COSMIC	98.777	Down-regulation
CMGC_DYRK_HIPK_HIPK2_ST	Q9P1Z0	ZBTB4	Q9H2X6	HIPK2	T797	G793W	793	Missense	distal	-4	no	115.078	114.604	PhosphoSitePlus;EPSD	ICGC;COSMIC	98.777	Down-regulation
CMGC_DYRK_HIPK_HIPK2_ST	Q01196	RUNX1	Q9H2X6	HIPK2	S21	M25V	25	Missense	distal	4	no	108.003	105.967	EPSD	ICGC	98.777	Down-regulation
CMGC_DYRK_HIPK_HIPK2_ST	P57682	KLF3	Q9H2X6	HIPK2	T40	E44K	44	Missense	distal	4	no	114.736	115.213	EPSD	ICGC;COSMIC	98.777	Up-regulation
CMGC_DYRK_HIPK_HIPK2_ST	P57682	KLF3	Q9H2X6	HIPK2	T49	E44K	44	Missense	distal	-5	no	117.825	115.983	EPSD	ICGC;COSMIC	98.777	Down-regulation
CMGC_DYRK_HIPK_HIPK2_ST	P57682	KLF3	Q9H2X6	HIPK2	S71	A75D	75	Missense	distal	4	no	114.441	112.592	EPSD;PhosphoSitePlus	ICGC;COSMIC	98.777	Down-regulation
CMGC_DYRK_HIPK_HIPK2_ST	P57682	KLF3	Q9H2X6	HIPK2	S78	A75D	75	Missense	distal	-3	no	118.243	118.256	PhosphoSitePlus;EPSD	ICGC;COSMIC	98.777	Up-regulation
CMGC_DYRK_HIPK_HIPK2_ST	P57682	KLF3	Q9H2X6	HIPK2	S108	P110T	110	Missense	proximal	2	no	116.929	116.351	EPSD;PhosphoSitePlus	ICGC;COSMIC	98.777	Down-regulation
CMGC_DYRK_HIPK_HIPK2_ST	P57682	KLF3	Q9H2X6	HIPK2	S111	P110T	110	Missense	proximal	-1	no	116.718	115.238	EPSD;PhosphoSitePlus	ICGC;COSMIC	98.777	Down-regulation
CMGC_DYRK_HIPK_HIPK2_ST	P57682	KLF3	Q9H2X6	HIPK2	S216	P217H	217	Missense	proximal	1	no	117.302	5.248	EPSD;PhosphoSitePlus	ICGC;COSMIC	98.777	Loss
CMGC_DYRK_HIPK_HIPK2_ST	P57682	KLF3	Q9H2X6	HIPK2	S216	P212A	212	Missense	distal	-4	no	117.302	117.202	EPSD;PhosphoSitePlus	ICGC	98.777	Down-regulation
CMGC_DYRK_HIPK_HIPK2_ST	P57682	KLF3	Q9H2X6	HIPK2	S224	P217H	217	Missense	distal	-7	no	114.033	110.808	EPSD;PhosphoSitePlus	ICGC;COSMIC	98.777	Down-regulation
CMGC_DYRK_HIPK_HIPK2_ST	P57682	KLF3	Q9H2X6	HIPK2	S250	R257W	257	Missense	distal	7	no	119.124	118.666	EPSD;PhosphoSitePlus	ICGC;COSMIC	98.777	Down-regulation
CMGC_DYRK_HIPK_HIPK2_ST	P57682	KLF3	Q9H2X6	HIPK2	S250	P245T	245	Missense	distal	-5	no	119.124	110.852	EPSD;PhosphoSitePlus	ICGC;COSMIC	98.777	Down-regulation
CMGC_DYRK_HIPK_HIPK2_ST	Q04724	TLE1	Q9H2X6	HIPK2	S258	P260L	260	Missense	proximal	2	no	101.653	100.104	EPSD	ICGC;COSMIC	98.777	Down-regulation
CMGC_DYRK_HIPK_HIPK2_ST	Q04724	TLE1	Q9H2X6	HIPK2	S258	P260T	260	Missense	proximal	2	no	101.653	101.075	EPSD	ICGC;COSMIC	98.777	Down-regulation
CMGC_DYRK_HIPK_HIPK2_ST	Q04724	TLE1	Q9H2X6	HIPK2	S258	S258F	258	Missense	central	0	yes	101.653	0.000	EPSD	ICGC;COSMIC	98.777	Loss
CMGC_DYRK_HIPK_HIPK2_ST	Q04724	TLE1	Q9H2X6	HIPK2	S258	E255A	255	Missense	distal	-3	no	101.653	101.945	EPSD	ICGC;COSMIC	98.777	Up-regulation
CMGC_DYRK_HIPK_HIPK2_ST	Q04724	TLE1	Q9H2X6	HIPK2	S259	P260L	260	Missense	proximal	1	no	103.835	-16.450	EPSD	ICGC;COSMIC	98.777	Loss
CMGC_DYRK_HIPK_HIPK2_ST	Q04724	TLE1	Q9H2X6	HIPK2	S259	H266P	266	Missense	distal	7	no	103.835	104.496	EPSD	ICGC	98.777	Up-regulation
CMGC_DYRK_HIPK_HIPK2_ST	Q04724	TLE1	Q9H2X6	HIPK2	S259	P260T	260	Missense	proximal	1	no	103.835	-47.500	EPSD	ICGC;COSMIC	98.777	Loss
CMGC_DYRK_HIPK_HIPK2_ST	Q04724	TLE1	Q9H2X6	HIPK2	S259	S258F	258	Missense	proximal	-1	no	103.835	101.573	EPSD	ICGC;COSMIC	98.777	Down-regulation
CMGC_DYRK_HIPK_HIPK2_ST	Q04724	TLE1	Q9H2X6	HIPK2	S259	E255A	255	Missense	distal	-4	no	103.835	103.837	EPSD	ICGC;COSMIC	98.777	Up-regulation
CMGC_DYRK_HIPK_HIPK2_ST	Q04724	TLE1	Q9H2X6	HIPK2	S263	P260L	260	Missense	distal	-3	no	107.281	107.500	EPSD	ICGC;COSMIC	98.777	Up-regulation
CMGC_DYRK_HIPK_HIPK2_ST	Q04724	TLE1	Q9H2X6	HIPK2	S263	H266P	266	Missense	distal	3	no	107.281	107.847	EPSD	ICGC	98.777	Up-regulation
CMGC_DYRK_HIPK_HIPK2_ST	Q04724	TLE1	Q9H2X6	HIPK2	S263	P260T	260	Missense	distal	-3	no	107.281	107.558	EPSD	ICGC;COSMIC	98.777	Up-regulation
CMGC_DYRK_HIPK_HIPK2_ST	Q04724	TLE1	Q9H2X6	HIPK2	S263	S258F	258	Missense	distal	-5	no	107.281	105.964	EPSD	ICGC;COSMIC	98.777	Down-regulation
CMGC_DYRK_HIPK_HIPK2_ST	Q04724	TLE1	Q9H2X6	HIPK2	S267	P260L	260	Missense	distal	-7	no	102.743	101.657	EPSD	ICGC;COSMIC	98.777	Down-regulation
CMGC_DYRK_HIPK_HIPK2_ST	Q04724	TLE1	Q9H2X6	HIPK2	S267	H266P	266	Missense	proximal	-1	no	102.743	105.245	EPSD	ICGC	98.777	Up-regulation
CMGC_DYRK_HIPK_HIPK2_ST	Q04724	TLE1	Q9H2X6	HIPK2	S267	P260T	260	Missense	distal	-7	no	102.743	101.436	EPSD	ICGC;COSMIC	98.777	Down-regulation
CMGC_DYRK_HIPK_HIPK2_ST	Q04724	TLE1	Q9H2X6	HIPK2	T312	K316N	316	Missense	distal	4	no	106.388	103.258	EPSD	ICGC;COSMIC	98.777	Down-regulation
CMGC_DYRK_HIPK_HIPK2_ST	Q04724	TLE1	Q9H2X6	HIPK2	T319	S324T	324	Missense	distal	5	no	111.778	111.908	EPSD	ICGC;COSMIC	98.777	Up-regulation
CMGC_DYRK_HIPK_HIPK2_ST	Q04724	TLE1	Q9H2X6	HIPK2	T319	K316N	316	Missense	distal	-3	no	111.778	112.148	EPSD	ICGC;COSMIC	98.777	Up-regulation
CMGC_DYRK_HIPK_HIPK2_ST	Q04724	TLE1	Q9H2X6	HIPK2	T321	S324T	324	Missense	distal	3	no	112.012	111.237	EPSD	ICGC;COSMIC	98.777	Down-regulation
CMGC_DYRK_HIPK_HIPK2_ST	Q04724	TLE1	Q9H2X6	HIPK2	T321	K316N	316	Missense	distal	-5	no	112.012	108.183	EPSD	ICGC;COSMIC	98.777	Down-regulation
CMGC_DYRK_HIPK_HIPK2_ST	Q04724	TLE1	Q9H2X6	HIPK2	T321	T328K	328	Missense	distal	7	no	112.012	111.926	EPSD	ICGC;COSMIC	98.777	Down-regulation
CMGC_DYRK_HIPK_HIPK2_ST	Q04724	TLE1	Q9H2X6	HIPK2	T328	S324T	324	Missense	distal	-4	no	118.841	118.844	EPSD	ICGC;COSMIC	98.777	Up-regulation
CMGC_DYRK_HIPK_HIPK2_ST	Q04724	TLE1	Q9H2X6	HIPK2	T328	P329Q	329	Missense	proximal	1	no	118.841	66.746	EPSD	ICGC;COSMIC	98.777	Loss
CMGC_DYRK_HIPK_HIPK2_ST	Q04724	TLE1	Q9H2X6	HIPK2	T328	T328K	328	Missense	central	0	yes	118.841	0.000	EPSD	ICGC;COSMIC	98.777	Loss
CMGC_DYRK_HIPK_HIPK2_ST	Q04724	TLE1	Q9H2X6	HIPK2	T334	R338L	338	Missense	distal	4	no	116.873	116.347	EPSD	ICGC	98.777	Down-regulation
CMGC_DYRK_HIPK_HIPK2_ST	Q04724	TLE1	Q9H2X6	HIPK2	T334	P329Q	329	Missense	distal	-5	no	116.873	114.498	EPSD	ICGC;COSMIC	98.777	Down-regulation
CMGC_DYRK_HIPK_HIPK2_ST	Q04724	TLE1	Q9H2X6	HIPK2	T334	T328K	328	Missense	distal	-6	no	116.873	117.230	EPSD	ICGC;COSMIC	98.777	Up-regulation
CMGC_DYRK_HIPK_HIPK2_ST	Q04724	TLE1	Q9H2X6	HIPK2	S416	D422G	422	Missense	distal	6	no	106.834	106.778	EPSD	ICGC;COSMIC	98.777	Down-regulation
CMGC_DYRK_HIPK_HIPK2_ST	Q04724	TLE1	Q9H2X6	HIPK2	S416	Y413N	413	Missense	distal	-3	no	106.834	106.483	EPSD	ICGC;COSMIC	98.777	Down-regulation
CMGC_DYRK_HIPK_HIPK2_ST	Q04724	TLE1	Q9H2X6	HIPK2	S416	R415C	415	Missense	proximal	-1	no	106.834	104.965	EPSD	ICGC;COSMIC	98.777	Down-regulation
CMGC_DYRK_HIPK_HIPK2_ST	P17096	HMGA1	Q9H2X6	HIPK2	T21	T21N	21	Missense	central	0	yes	100.181	0.000	EPSD	ICGC;COSMIC	98.777	Loss
CMGC_DYRK_HIPK_HIPK2_ST	P17096	HMGA1	Q9H2X6	HIPK2	S36	A40V	40	Missense	distal	4	no	115.973	112.990	EPSD;PhosphoSitePlus	ICGC	98.777	Down-regulation
CMGC_DYRK_HIPK_HIPK2_ST	P17096	HMGA1	Q9H2X6	HIPK2	T53	G59V	59	Missense	distal	6	no	118.348	118.243	EPSD;PhosphoSitePlus	ICGC;COSMIC	98.777	Down-regulation
CMGC_DYRK_HIPK_HIPK2_ST	P17096	HMGA1	Q9H2X6	HIPK2	T53	P48S	48	Missense	distal	-5	no	118.348	114.085	EPSD;PhosphoSitePlus	ICGC;COSMIC	98.777	Down-regulation
CMGC_DYRK_HIPK_HIPK2_ST	P17096	HMGA1	Q9H2X6	HIPK2	T72	K71N	71	Missense	proximal	-1	no	106.663	105.837	EPSD	ICGC	98.777	Down-regulation
CMGC_DYRK_HIPK_HIPK2_ST	P17096	HMGA1	Q9H2X6	HIPK2	T78	K71N	71	Missense	distal	-7	no	121.586	120.478	PhosphoSitePlus;EPSD	ICGC	98.777	Down-regulation
CMGC_DYRK_HIPK_HIPK2_ST	P46531	NOTCH1	Q9H2X6	HIPK2	T518	Q513K	513	Missense	distal	-5	no	99.739	99.174	EPSD	ICGC	98.777	Down-regulation
CMGC_DYRK_HIPK_HIPK2_ST	P46531	NOTCH1	Q9H2X6	HIPK2	T1861	P1862S	1862	Missense	proximal	1	no	100.189	82.908	EPSD	ICGC	98.777	Loss
CMGC_DYRK_HIPK_HIPK2_ST	P46531	NOTCH1	Q9H2X6	HIPK2	T1861	P1862Q	1862	Missense	proximal	1	no	100.189	48.093	EPSD	ICGC;COSMIC	98.777	Loss
CMGC_DYRK_HIPK_HIPK2_ST	P46531	NOTCH1	Q9H2X6	HIPK2	T1997	G1995V	1995	Missense	proximal	-2	no	100.798	100.270	EPSD	ICGC;COSMIC	98.777	Down-regulation
CMGC_DYRK_HIPK_HIPK2_ST	P46531	NOTCH1	Q9H2X6	HIPK2	T1997	L2001M	2001	Missense	distal	4	no	100.798	100.983	EPSD	ICGC	98.777	Up-regulation
CMGC_DYRK_HIPK_HIPK2_ST	P46531	NOTCH1	Q9H2X6	HIPK2	T1997	T1996K	1996	Missense	proximal	-1	no	100.798	102.373	EPSD	ICGC	98.777	Up-regulation
CMGC_DYRK_HIPK_HIPK2_ST	P46531	NOTCH1	Q9H2X6	HIPK2	S2121	H2125Q	2125	Missense	distal	4	no	94.401	101.803	EPSD	ICGC;GDSC;CCLE	98.777	Gain
CMGC_DYRK_HIPK_HIPK2_ST	P46531	NOTCH1	Q9H2X6	HIPK2	T2132	H2125Q	2125	Missense	distal	-7	no	95.986	99.453	EPSD	ICGC;GDSC;CCLE	98.777	Gain
CMGC_DYRK_HIPK_HIPK2_ST	P46531	NOTCH1	Q9H2X6	HIPK2	S2136	G2130W	2130	Missense	distal	-6	no	104.087	103.605	EPSD	ICGC;COSMIC	98.777	Down-regulation
CMGC_DYRK_HIPK_HIPK2_ST	P46531	NOTCH1	Q9H2X6	HIPK2	S2136	P2138Q	2138	Missense	proximal	2	no	104.087	103.820	EPSD	ICGC;COSMIC	98.777	Down-regulation
CMGC_DYRK_HIPK_HIPK2_ST	P46531	NOTCH1	Q9H2X6	HIPK2	S2141	P2138Q	2138	Missense	distal	-3	no	104.746	104.332	EPSD	ICGC;COSMIC	98.777	Down-regulation
CMGC_DYRK_HIPK_HIPK2_ST	P46531	NOTCH1	Q9H2X6	HIPK2	S2221	P2216T	2216	Missense	distal	-5	no	105.935	97.663	EPSD	ICGC	98.777	Loss
CMGC_DYRK_HIPK_HIPK2_ST	P46531	NOTCH1	Q9H2X6	HIPK2	S2221	L2218R	2218	Missense	distal	-3	no	105.935	105.867	EPSD	ICGC	98.777	Down-regulation
CMGC_DYRK_HIPK_HIPK2_ST	P46531	NOTCH1	Q9H2X6	HIPK2	T2511	P2512L	2512	Missense	proximal	1	no	124.756	4.471	PhosphoSitePlus	ICGC;COSMIC	98.777	Loss
CMGC_DYRK_HIPK_HIPK2_ST	P46531	NOTCH1	Q9H2X6	HIPK2	T2511	S2516F	2516	Missense	distal	5	no	124.756	124.887	PhosphoSitePlus	ICGC	98.777	Up-regulation
CMGC_DYRK_HIPK_HIPK2_ST	P46531	NOTCH1	Q9H2X6	HIPK2	T2511	P2512T	2512	Missense	proximal	1	no	124.756	-26.579	PhosphoSitePlus	ICGC;COSMIC	98.777	Loss
CMGC_DYRK_HIPK_HIPK2_ST	P46531	NOTCH1	Q9H2X6	HIPK2	S2513	P2512L	2512	Missense	proximal	-1	no	119.291	117.901	EPSD	ICGC;COSMIC	98.777	Down-regulation
CMGC_DYRK_HIPK_HIPK2_ST	P46531	NOTCH1	Q9H2X6	HIPK2	S2513	S2516F	2516	Missense	distal	3	no	119.291	118.543	EPSD	ICGC	98.777	Down-regulation
CMGC_DYRK_HIPK_HIPK2_ST	P46531	NOTCH1	Q9H2X6	HIPK2	S2513	P2512T	2512	Missense	proximal	-1	no	119.291	117.811	EPSD	ICGC;COSMIC	98.777	Down-regulation
CMGC_DYRK_HIPK_HIPK2_ST	P46531	NOTCH1	Q9H2X6	HIPK2	S2523	S2516F	2516	Missense	distal	-7	no	102.633	100.691	EPSD	ICGC	98.777	Down-regulation
CMGC_DYRK_HIPK_HIPK2_ST	P46531	NOTCH1	Q9H2X6	HIPK2	S2523	P2525Q	2525	Missense	proximal	2	no	102.633	102.366	EPSD	ICGC;COSMIC	98.777	Down-regulation
CMGC_DYRK_HIPK_HIPK2_ST	P46531	NOTCH1	Q9H2X6	HIPK2	S2524	P2525Q	2525	Missense	proximal	1	no	104.924	52.828	EPSD	ICGC;COSMIC	98.777	Loss
CMGC_DYRK_HIPK_HIPK2_ST	P56545	CTBP2	Q9H2X6	HIPK2	S106	G105A	105	Missense	proximal	-1	no	100.528	100.084	EPSD	ICGC;COSMIC	98.777	Down-regulation
CMGC_DYRK_HIPK_HIPK2_ST	P56545	CTBP2	Q9H2X6	HIPK2	S106	R103L	103	Missense	distal	-3	no	100.528	100.597	EPSD	ICGC;COSMIC	98.777	Up-regulation
CMGC_DYRK_HIPK_HIPK2_ST	P56545	CTBP2	Q9H2X6	HIPK2	S106	V100A	100	Missense	distal	-6	no	100.528	100.765	EPSD	ICGC;COSMIC	98.777	Up-regulation
CMGC_DYRK_HIPK_HIPK2_ST	P56545	CTBP2	Q9H2X6	HIPK2	S106	N110K	110	Missense	distal	4	no	100.528	103.657	EPSD	ICGC;COSMIC	98.777	Up-regulation
CMGC_DYRK_HIPK_HIPK2_ST	P56545	CTBP2	Q9H2X6	HIPK2	S106	S106R	106	Missense	central	0	yes	100.528	0.000	EPSD	ICGC;COSMIC	98.777	Loss
CMGC_DYRK_HIPK_HIPK2_ST	P56545	CTBP2	Q9H2X6	HIPK2	S428	A426G	426	Missense	proximal	-2	no	116.763	116.934	PhosphoSitePlus	ICGC;COSMIC	98.777	Up-regulation
CMGC_DYRK_HIPK_HIPK2_ST	P56545	CTBP2	Q9H2X6	HIPK2	S428	K434I	434	Missense	distal	6	no	116.763	116.672	PhosphoSitePlus	ICGC;COSMIC	98.777	Down-regulation
CMGC_DYRK_HIPK_HIPK2_ST	P56545	CTBP2	Q9H2X6	HIPK2	S428	P423T	423	Missense	distal	-5	no	116.763	108.491	PhosphoSitePlus	ICGC;COSMIC	98.777	Down-regulation
CMGC_DYRK_HIPK_HIPK2_ST	P56545	CTBP2	Q9H2X6	HIPK2	S428	T433S	433	Missense	distal	5	no	116.763	116.633	PhosphoSitePlus	ICGC;COSMIC	98.777	Down-regulation
CMGC_DYRK_HIPK_HIPK2_ST	P29590	PML	Q9H2X6	HIPK2	S388	C389R	389	Missense	proximal	1	no	-17.059	98.923	EPSD	ICGC;COSMIC	98.777	Gain
CMGC_DYRK_HIPK_HIPK2_ST	P29590	PML	Q9H2X6	HIPK2	S403	P410A	410	Missense	distal	7	no	106.259	106.168	EPSD	ICGC;COSMIC	98.777	Down-regulation
CMGC_DYRK_HIPK_HIPK2_ST	P29590	PML	Q9H2X6	HIPK2	S403	V398L	398	Missense	distal	-5	no	106.259	105.133	EPSD	ICGC	98.777	Down-regulation
CMGC_DYRK_HIPK_HIPK2_ST	P29590	PML	Q9H2X6	HIPK2	S403	A407S	407	Missense	distal	4	no	106.259	107.260	EPSD	ICGC;COSMIC	98.777	Up-regulation
CMGC_DYRK_HIPK_HIPK2_ST	P29590	PML	Q9H2X6	HIPK2	S403	A407T	407	Missense	distal	4	no	106.259	105.502	EPSD	ICGC;COSMIC	98.777	Down-regulation
CMGC_DYRK_HIPK_HIPK2_ST	P29590	PML	Q9H2X6	HIPK2	T409	P410A	410	Missense	proximal	1	no	115.765	-12.759	EPSD	ICGC;COSMIC	98.777	Loss
CMGC_DYRK_HIPK_HIPK2_ST	P29590	PML	Q9H2X6	HIPK2	T409	A407S	407	Missense	proximal	-2	no	115.765	115.908	EPSD	ICGC;COSMIC	98.777	Up-regulation
CMGC_DYRK_HIPK_HIPK2_ST	P29590	PML	Q9H2X6	HIPK2	T409	A407T	407	Missense	proximal	-2	no	115.765	115.546	EPSD	ICGC;COSMIC	98.777	Down-regulation
CMGC_DYRK_HIPK_HIPK2_ST	P29590	PML	Q9H2X6	HIPK2	S505	Q508H	508	Missense	distal	3	no	102.426	101.294	EPSD	ICGC	98.777	Down-regulation
CMGC_DYRK_HIPK_HIPK2_ST	P29590	PML	Q9H2X6	HIPK2	S505	S505F	505	Missense	central	0	yes	102.426	0.000	EPSD	ICGC	98.777	Loss
CMGC_DYRK_HIPK_HIPK2_ST	P29590	PML	Q9H2X6	HIPK2	S518	P525L	525	Missense	distal	7	no	111.531	111.353	EPSD	ICGC;COSMIC;GDSC;CCLE	98.777	Down-regulation
CMGC_DYRK_HIPK_HIPK2_ST	P29590	PML	Q9H2X6	HIPK2	S530	P525L	525	Missense	distal	-5	no	109.869	102.446	EPSD	ICGC;COSMIC;GDSC;CCLE	98.777	Down-regulation
CMGC_DYRK_HIPK_HIPK2_ST	P29590	PML	Q9H2X6	HIPK2	S530	S535L	535	Missense	distal	5	no	109.869	109.982	EPSD	ICGC;COSMIC	98.777	Up-regulation
CMGC_DYRK_HIPK_HIPK2_ST	P29590	PML	Q9H2X6	HIPK2	S530	P526L	526	Missense	distal	-4	no	109.869	109.732	EPSD	ICGC	98.777	Down-regulation
CMGC_DYRK_HIPK_HIPK2_ST	P29590	PML	Q9H2X6	HIPK2	S560	R555C	555	Missense	distal	-5	no	104.125	90.475	EPSD	ICGC;COSMIC	98.777	Loss
CMGC_DYRK_HIPK_HIPK2_ST	P29590	PML	Q9H2X6	HIPK2	S560	V556F	556	Missense	distal	-4	no	104.125	104.180	EPSD	ICGC;COSMIC	98.777	Up-regulation
CMGC_DYRK_HIPK_HIPK2_ST	P29590	PML	Q9H2X6	HIPK2	S560	R555H	555	Missense	distal	-5	no	104.125	93.289	EPSD	ICGC;COSMIC	98.777	Loss
CMGC_DYRK_HIPK_HIPK2_ST	P29590	PML	Q9H2X6	HIPK2	S561	R555C	555	Missense	distal	-6	no	104.036	103.611	EPSD	ICGC;COSMIC	98.777	Down-regulation
CMGC_DYRK_HIPK_HIPK2_ST	P29590	PML	Q9H2X6	HIPK2	S561	V556F	556	Missense	distal	-5	no	104.036	104.754	EPSD	ICGC;COSMIC	98.777	Up-regulation
CMGC_DYRK_HIPK_HIPK2_ST	P29590	PML	Q9H2X6	HIPK2	S561	R555H	555	Missense	distal	-6	no	104.036	103.739	EPSD	ICGC;COSMIC	98.777	Down-regulation
CMGC_DYRK_HIPK_HIPK2_ST	P29590	PML	Q9H2X6	HIPK2	T592	L593P	593	Missense	proximal	1	no	-16.362	103.923	EPSD	ICGC	98.777	Gain
CMGC_DYRK_HIPK_HIPK2_ST	P51608	MECP2	Q9H2X6	HIPK2	S49	A50G	50	Missense	proximal	1	no	-11.544	105.847	EPSD	ICGC;COSMIC	98.777	Gain
CMGC_DYRK_HIPK_HIPK2_ST	P51608	MECP2	Q9H2X6	HIPK2	S68	A73V	73	Missense	distal	5	no	104.164	104.262	EPSD	ICGC;COSMIC	98.777	Up-regulation
CMGC_DYRK_HIPK_HIPK2_ST	P51608	MECP2	Q9H2X6	HIPK2	S68	P75T	75	Missense	distal	7	no	104.164	104.166	EPSD	ICGC	98.777	Up-regulation
CMGC_DYRK_HIPK_HIPK2_ST	P51608	MECP2	Q9H2X6	HIPK2	S80	R85C	85	Missense	distal	5	no	119.763	119.947	EPSD;PhosphoSitePlus	ICGC;COSMIC;CCLE	98.777	Up-regulation
CMGC_DYRK_HIPK_HIPK2_ST	P51608	MECP2	Q9H2X6	HIPK2	S80	R85H	85	Missense	distal	5	no	119.763	119.855	EPSD;PhosphoSitePlus	ICGC;COSMIC	98.777	Up-regulation
CMGC_DYRK_HIPK_HIPK2_ST	P51608	MECP2	Q9H2X6	HIPK2	S80	A73V	73	Missense	distal	-7	no	119.763	118.754	EPSD;PhosphoSitePlus	ICGC;COSMIC	98.777	Down-regulation
CMGC_DYRK_HIPK_HIPK2_ST	P51608	MECP2	Q9H2X6	HIPK2	S80	P75T	75	Missense	distal	-5	no	119.763	111.491	EPSD;PhosphoSitePlus	ICGC	98.777	Down-regulation
CMGC_DYRK_HIPK_HIPK2_ST	P51608	MECP2	Q9H2X6	HIPK2	S80	E76K	76	Missense	distal	-4	no	119.763	119.839	EPSD;PhosphoSitePlus	ICGC;COSMIC	98.777	Up-regulation
CMGC_DYRK_HIPK_HIPK2_ST	P51608	MECP2	Q9H2X6	HIPK2	S80	S78A	78	Missense	proximal	-2	no	119.763	119.620	EPSD;PhosphoSitePlus	ICGC;COSMIC	98.777	Down-regulation
CMGC_DYRK_HIPK_HIPK2_ST	P51608	MECP2	Q9H2X6	HIPK2	S80	R84W	84	Missense	distal	4	no	119.763	110.901	EPSD;PhosphoSitePlus	ICGC;COSMIC	98.777	Down-regulation
CMGC_DYRK_HIPK_HIPK2_ST	P51608	MECP2	Q9H2X6	HIPK2	S164	R167H	167	Missense	distal	3	no	106.321	105.833	EPSD	ICGC;COSMIC	98.777	Down-regulation
CMGC_DYRK_HIPK_HIPK2_ST	P51608	MECP2	Q9H2X6	HIPK2	S164	T158M	158	Missense	distal	-6	no	106.321	106.302	EPSD	ICGC;COSMIC;CCLE	98.777	Down-regulation
CMGC_DYRK_HIPK_HIPK2_ST	P51608	MECP2	Q9H2X6	HIPK2	S164	T158K	158	Missense	distal	-6	no	106.321	106.678	EPSD	ICGC	98.777	Up-regulation
CMGC_DYRK_HIPK_HIPK2_ST	P51608	MECP2	Q9H2X6	HIPK2	S178	P176S	176	Missense	proximal	-2	no	113.419	113.494	EPSD	ICGC;COSMIC	98.777	Up-regulation
CMGC_DYRK_HIPK_HIPK2_ST	P51608	MECP2	Q9H2X6	HIPK2	T184	R190S	190	Missense	distal	6	no	104.632	105.073	EPSD	ICGC	98.777	Up-regulation
CMGC_DYRK_HIPK_HIPK2_ST	P51608	MECP2	Q9H2X6	HIPK2	T184	P191L	191	Missense	distal	7	no	104.632	104.454	EPSD	ICGC;COSMIC	98.777	Down-regulation
CMGC_DYRK_HIPK_HIPK2_ST	P51608	MECP2	Q9H2X6	HIPK2	S204	A202V	202	Missense	proximal	-2	no	100.574	100.216	EPSD	ICGC	98.777	Down-regulation
CMGC_DYRK_HIPK_HIPK2_ST	P51608	MECP2	Q9H2X6	HIPK2	S204	Q208H	208	Missense	distal	4	no	100.574	93.172	EPSD	ICGC;COSMIC	98.777	Loss
CMGC_DYRK_HIPK_HIPK2_ST	P51608	MECP2	Q9H2X6	HIPK2	S216	P217S	217	Missense	proximal	1	no	117.624	100.344	PhosphoSitePlus;EPSD	ICGC;COSMIC	98.777	Down-regulation
CMGC_DYRK_HIPK_HIPK2_ST	P51608	MECP2	Q9H2X6	HIPK2	T228	E235K	235	Missense	distal	7	no	99.577	99.391	EPSD	ICGC;COSMIC	98.777	Down-regulation
CMGC_DYRK_HIPK_HIPK2_ST	P51608	MECP2	Q9H2X6	HIPK2	T228	M224I	224	Missense	distal	-4	no	99.577	99.755	EPSD	ICGC;COSMIC	98.777	Up-regulation
CMGC_DYRK_HIPK_HIPK2_ST	P51608	MECP2	Q9H2X6	HIPK2	S229	E235K	235	Missense	distal	6	no	105.967	105.596	EPSD	ICGC;COSMIC	98.777	Down-regulation
CMGC_DYRK_HIPK_HIPK2_ST	P51608	MECP2	Q9H2X6	HIPK2	S229	G236R	236	Missense	distal	7	no	105.967	105.789	EPSD	ICGC	98.777	Down-regulation
CMGC_DYRK_HIPK_HIPK2_ST	P51608	MECP2	Q9H2X6	HIPK2	S229	M224I	224	Missense	distal	-5	no	105.967	111.355	EPSD	ICGC;COSMIC	98.777	Up-regulation
CMGC_DYRK_HIPK_HIPK2_ST	P51608	MECP2	Q9H2X6	HIPK2	S291	E298D	298	Missense	distal	7	no	99.251	98.927	EPSD	ICGC;COSMIC	98.777	Down-regulation
CMGC_DYRK_HIPK_HIPK2_ST	P51608	MECP2	Q9H2X6	HIPK2	S332	S326C	326	Missense	distal	-6	no	99.281	98.705	EPSD	ICGC	98.777	Loss
CMGC_DYRK_HIPK_HIPK2_ST	P51608	MECP2	Q9H2X6	HIPK2	S332	T327N	327	Missense	distal	-5	no	99.281	100.783	EPSD	ICGC;COSMIC	98.777	Up-regulation
CMGC_DYRK_HIPK_HIPK2_ST	P51608	MECP2	Q9H2X6	HIPK2	S332	G333R	333	Missense	proximal	1	no	99.281	97.877	EPSD	ICGC	98.777	Loss
CMGC_DYRK_HIPK_HIPK2_ST	P51608	MECP2	Q9H2X6	HIPK2	S332	L328F	328	Missense	distal	-4	no	99.281	99.090	EPSD	ICGC	98.777	Down-regulation
CMGC_DYRK_HIPK_HIPK2_ST	P51608	MECP2	Q9H2X6	HIPK2	S332	L328I	328	Missense	distal	-4	no	99.281	99.189	EPSD	ICGC	98.777	Down-regulation
CMGC_DYRK_HIPK_HIPK2_ST	P51608	MECP2	Q9H2X6	HIPK2	S350	R354C	354	Missense	distal	4	no	107.752	100.139	EPSD	ICGC;COSMIC;CCLE	98.777	Down-regulation
CMGC_DYRK_HIPK_HIPK2_ST	P51608	MECP2	Q9H2X6	HIPK2	S350	S350R	350	Missense	central	0	yes	107.752	0.000	EPSD	ICGC;COSMIC	98.777	Loss
CMGC_DYRK_HIPK_HIPK2_ST	P51608	MECP2	Q9H2X6	HIPK2	S350	S356R	356	Missense	distal	6	no	107.752	107.311	EPSD	ICGC	98.777	Down-regulation
CMGC_DYRK_HIPK_HIPK2_ST	P51608	MECP2	Q9H2X6	HIPK2	S350	S346N	346	Missense	distal	-4	no	107.752	107.717	EPSD	ICGC	98.777	Down-regulation
CMGC_DYRK_HIPK_HIPK2_ST	P51608	MECP2	Q9H2X6	HIPK2	S360	S360L	360	Missense	central	0	yes	109.308	0.000	EPSD	ICGC;COSMIC	98.777	Loss
CMGC_DYRK_HIPK_HIPK2_ST	P51608	MECP2	Q9H2X6	HIPK2	S360	R354C	354	Missense	distal	-6	no	109.308	108.883	EPSD	ICGC;COSMIC;CCLE	98.777	Down-regulation
CMGC_DYRK_HIPK_HIPK2_ST	P51608	MECP2	Q9H2X6	HIPK2	S360	P361L	361	Missense	proximal	1	no	109.308	-10.977	EPSD	ICGC	98.777	Loss
CMGC_DYRK_HIPK_HIPK2_ST	P51608	MECP2	Q9H2X6	HIPK2	S360	S356R	356	Missense	distal	-4	no	109.308	109.183	EPSD	ICGC	98.777	Down-regulation
CMGC_DYRK_HIPK_HIPK2_ST	P51608	MECP2	Q9H2X6	HIPK2	S360	P362S	362	Missense	proximal	2	no	109.308	109.273	EPSD	ICGC;COSMIC	98.777	Down-regulation
CMGC_DYRK_HIPK_HIPK2_ST	P51608	MECP2	Q9H2X6	HIPK2	S360	K363N	363	Missense	distal	3	no	109.308	109.221	EPSD	ICGC	98.777	Down-regulation
CMGC_DYRK_HIPK_HIPK2_ST	P51608	MECP2	Q9H2X6	HIPK2	S401	Q406H	406	Missense	distal	5	no	105.338	105.615	EPSD	ICGC;COSMIC	98.777	Up-regulation
CMGC_DYRK_HIPK_HIPK2_ST	P51608	MECP2	Q9H2X6	HIPK2	S410	E415Q	415	Missense	distal	5	no	101.580	101.556	EPSD	ICGC;COSMIC	98.777	Down-regulation
CMGC_DYRK_HIPK_HIPK2_ST	P51608	MECP2	Q9H2X6	HIPK2	S410	V412I	412	Missense	proximal	2	no	101.580	101.830	EPSD	ICGC;COSMIC	98.777	Up-regulation
CMGC_DYRK_HIPK_HIPK2_ST	P51608	MECP2	Q9H2X6	HIPK2	S410	K417M	417	Missense	distal	7	no	101.580	101.260	EPSD	ICGC;COSMIC	98.777	Down-regulation
CMGC_DYRK_HIPK_HIPK2_ST	P51608	MECP2	Q9H2X6	HIPK2	S410	Q406H	406	Missense	distal	-4	no	101.580	101.197	EPSD	ICGC;COSMIC	98.777	Down-regulation
CMGC_DYRK_HIPK_HIPK2_ST	P04637	TP53	Q9H2X6	HIPK2	S33	P34L	34	Missense	proximal	1	no	103.633	-16.652	EPSD	ICGC;COSMIC	98.777	Loss
CMGC_DYRK_HIPK_HIPK2_ST	P04637	TP53	Q9H2X6	HIPK2	S33	S33F	33	Missense	central	0	yes	103.633	0.000	EPSD	ICGC;COSMIC	98.777	Loss
CMGC_DYRK_HIPK_HIPK2_ST	P04637	TP53	Q9H2X6	HIPK2	S33	N30I	30	Missense	distal	-3	no	103.633	103.509	EPSD	ICGC	98.777	Down-regulation
CMGC_DYRK_HIPK_HIPK2_ST	P04637	TP53	Q9H2X6	HIPK2	S46	D48G	48	Missense	proximal	2	no	116.500	116.892	PhosphoSitePlus	ICGC;COSMIC	98.777	Up-regulation
CMGC_DYRK_HIPK_HIPK2_ST	P04637	TP53	Q9H2X6	HIPK2	S46	Q52K	52	Missense	distal	6	no	116.500	116.398	PhosphoSitePlus	ICGC	98.777	Down-regulation
CMGC_DYRK_HIPK_HIPK2_ST	P04637	TP53	Q9H2X6	HIPK2	T150	R156L	156	Missense	distal	6	no	104.776	104.933	EPSD	ICGC;COSMIC	98.777	Up-regulation
CMGC_DYRK_HIPK_HIPK2_ST	P04637	TP53	Q9H2X6	HIPK2	T150	L145Q	145	Missense	distal	-5	no	104.776	109.825	EPSD	ICGC;COSMIC	98.777	Up-regulation
CMGC_DYRK_HIPK_HIPK2_ST	P04637	TP53	Q9H2X6	HIPK2	T150	P152R	152	Missense	proximal	2	no	104.776	102.249	EPSD	ICGC;COSMIC	98.777	Down-regulation
CMGC_DYRK_HIPK_HIPK2_ST	P04637	TP53	Q9H2X6	HIPK2	T150	G154S	154	Missense	distal	4	no	104.776	104.703	EPSD	ICGC;COSMIC	98.777	Down-regulation
CMGC_DYRK_HIPK_HIPK2_ST	P04637	TP53	Q9H2X6	HIPK2	T150	V157A	157	Missense	distal	7	no	104.776	105.104	EPSD	ICGC;COSMIC	98.777	Up-regulation
CMGC_DYRK_HIPK_HIPK2_ST	P04637	TP53	Q9H2X6	HIPK2	T150	P151F	151	Missense	proximal	1	no	104.776	47.423	EPSD	ICGC;COSMIC	98.777	Loss
CMGC_DYRK_HIPK_HIPK2_ST	P04637	TP53	Q9H2X6	HIPK2	T150	V147G	147	Missense	distal	-3	no	104.776	104.423	EPSD	ICGC;COSMIC;GDSC;CCLE	98.777	Down-regulation
CMGC_DYRK_HIPK_HIPK2_ST	P04637	TP53	Q9H2X6	HIPK2	S313	T312I	312	Missense	proximal	-1	no	98.044	98.848	EPSD	ICGC;COSMIC	98.777	Gain
CMGC_DYRK_HIPK_HIPK2_ST	P04637	TP53	Q9H2X6	HIPK2	S314	T312I	312	Missense	proximal	-2	no	99.315	99.526	EPSD	ICGC;COSMIC	98.777	Up-regulation
CMGC_DYRK_HIPK_HIPK2_ST	P04637	TP53	Q9H2X6	HIPK2	S315	T312I	312	Missense	distal	-3	no	106.507	106.220	EPSD	ICGC;COSMIC	98.777	Down-regulation
CMGC_DYRK_HIPK_HIPK2_ST	P04637	TP53	Q9H2X6	HIPK2	S315	P322T	322	Missense	distal	7	no	106.507	106.508	EPSD	ICGC	98.777	Up-regulation
CMGC_DYRK_HIPK_HIPK2_ST	P04637	TP53	Q9H2X6	HIPK2	S376	T377P	377	Missense	proximal	1	no	-47.768	103.567	EPSD	ICGC;COSMIC	98.777	Gain
CMGC_DYRK_HIPK_HIPK2_ST	O15297	PPM1D	Q9H2X6	HIPK2	S54	G61A	61	Missense	distal	7	no	107.743	108.039	EPSD	ICGC	98.777	Up-regulation
CMGC_DYRK_HIPK_HIPK2_ST	O15297	PPM1D	Q9H2X6	HIPK2	S54	L58F	58	Missense	distal	4	no	107.743	103.798	EPSD	ICGC;COSMIC	98.777	Down-regulation
CMGC_DYRK_HIPK_HIPK2_ST	O15297	PPM1D	Q9H2X6	HIPK2	S64	G61A	61	Missense	distal	-3	no	104.842	104.972	EPSD	ICGC	98.777	Up-regulation
CMGC_DYRK_HIPK_HIPK2_ST	O15297	PPM1D	Q9H2X6	HIPK2	S64	S64L	64	Missense	central	0	yes	104.842	0.000	EPSD	ICGC;COSMIC	98.777	Loss
CMGC_DYRK_HIPK_HIPK2_ST	O15297	PPM1D	Q9H2X6	HIPK2	S64	L58F	58	Missense	distal	-6	no	104.842	104.785	EPSD	ICGC;COSMIC	98.777	Down-regulation
CMGC_DYRK_HIPK_HIPK2_ST	O15297	PPM1D	Q9H2X6	HIPK2	S85	C92R	92	Missense	distal	7	no	118.760	119.082	PhosphoSitePlus	ICGC;COSMIC	98.777	Up-regulation
CMGC_DYRK_HIPK_HIPK2_ST	O15297	PPM1D	Q9H2X6	HIPK2	S85	P88S	88	Missense	distal	3	no	118.760	119.072	PhosphoSitePlus	ICGC;COSMIC	98.777	Up-regulation
CMGC_DYRK_HIPK_HIPK2_ST	O15297	PPM1D	Q9H2X6	HIPK2	S85	P80L	80	Missense	distal	-5	no	118.760	111.336	PhosphoSitePlus	ICGC;COSMIC	98.777	Down-regulation
CMGC_DYRK_HIPK_HIPK2_ST	O15297	PPM1D	Q9H2X6	HIPK2	T517	L513V	513	Missense	distal	-4	no	102.327	102.081	EPSD	ICGC;COSMIC	98.777	Down-regulation
CMGC_DYRK_HIPK_HIPK2_ST	O15297	PPM1D	Q9H2X6	HIPK2	T529	E527A	527	Missense	proximal	-2	no	112.788	112.710	EPSD	ICGC;COSMIC	98.777	Down-regulation
CMGC_DYRK_HIPK_HIPK2_ST	O15297	PPM1D	Q9H2X6	HIPK2	T529	R536S	536	Missense	distal	7	no	112.788	113.393	EPSD	ICGC	98.777	Up-regulation
CMGC_DYRK_HIPK_HIPK2_ST	O15297	PPM1D	Q9H2X6	HIPK2	T529	R536K	536	Missense	distal	7	no	112.788	113.269	EPSD	ICGC	98.777	Up-regulation
CMGC_DYRK_HIPK_HIPK2_ST	O15297	PPM1D	Q9H2X6	HIPK2	S559	G554C	554	Missense	distal	-5	no	104.541	95.444	EPSD	ICGC;COSMIC	98.777	Loss
CMGC_DYRK_HIPK_HIPK2_ST	Q96EB6	SIRT1	Q9H2X6	HIPK2	S14	A18G	18	Missense	distal	4	no	110.738	111.812	EPSD	ICGC	98.777	Up-regulation
CMGC_DYRK_HIPK_HIPK2_ST	Q96EB6	SIRT1	Q9H2X6	HIPK2	S14	S16P	16	Missense	proximal	2	no	110.738	110.774	EPSD	ICGC	98.777	Up-regulation
CMGC_DYRK_HIPK_HIPK2_ST	Q96EB6	SIRT1	Q9H2X6	HIPK2	S26	S27P	27	Missense	proximal	1	no	89.477	106.757	EPSD	ICGC	98.777	Gain
CMGC_DYRK_HIPK_HIPK2_ST	Q96EB6	SIRT1	Q9H2X6	HIPK2	S27	S27F	27	Missense	central	0	yes	111.719	0.000	EPSD;PhosphoSitePlus	ICGC;COSMIC	98.777	Loss
CMGC_DYRK_HIPK_HIPK2_ST	Q96EB6	SIRT1	Q9H2X6	HIPK2	S27	P28S	28	Missense	proximal	1	no	111.719	94.439	EPSD;PhosphoSitePlus	ICGC;COSMIC	98.777	Loss
CMGC_DYRK_HIPK_HIPK2_ST	Q96EB6	SIRT1	Q9H2X6	HIPK2	S27	S27P	27	Missense	central	0	yes	111.719	0.000	EPSD;PhosphoSitePlus	ICGC	98.777	Loss
CMGC_DYRK_HIPK_HIPK2_ST	Q96EB6	SIRT1	Q9H2X6	HIPK2	S47	G53W	53	Missense	distal	6	no	111.144	110.294	EPSD	ICGC	98.777	Down-regulation
CMGC_DYRK_HIPK_HIPK2_ST	Q96EB6	SIRT1	Q9H2X6	HIPK2	S47	R46C	46	Missense	proximal	-1	no	111.144	109.275	EPSD	ICGC;COSMIC	98.777	Down-regulation
CMGC_DYRK_HIPK_HIPK2_ST	Q96EB6	SIRT1	Q9H2X6	HIPK2	S47	R46H	46	Missense	proximal	-1	no	111.144	109.854	EPSD	ICGC;COSMIC	98.777	Down-regulation
CMGC_DYRK_HIPK_HIPK2_ST	Q96EB6	SIRT1	Q9H2X6	HIPK2	S47	P51L	51	Missense	distal	4	no	111.144	110.144	EPSD	ICGC;COSMIC	98.777	Down-regulation
CMGC_DYRK_HIPK_HIPK2_ST	Q96EB6	SIRT1	Q9H2X6	HIPK2	S47	R46S	46	Missense	proximal	-1	no	111.144	112.672	EPSD	ICGC;COSMIC	98.777	Up-regulation
CMGC_DYRK_HIPK_HIPK2_ST	Q9H2X6	HIPK2	Q9H2X6	HIPK2	S16	V14A	14	Missense	proximal	-2	no	98.446	98.804	EPSD	ICGC	98.777	Gain
CMGC_DYRK_HIPK_HIPK2_ST	Q9H2X6	HIPK2	Q9H2X6	HIPK2	S294	N291K	291	Missense	distal	-3	no	105.124	104.755	EPSD	ICGC;COSMIC	98.777	Down-regulation
CMGC_DYRK_HIPK_HIPK2_ST	Q9H2X6	HIPK2	Q9H2X6	HIPK2	S294	P297T	297	Missense	distal	3	no	105.124	104.660	EPSD	ICGC	98.777	Down-regulation
CMGC_DYRK_HIPK_HIPK2_ST	Q9H2X6	HIPK2	Q9H2X6	HIPK2	S294	P297H	297	Missense	distal	3	no	105.124	104.558	EPSD	ICGC	98.777	Down-regulation
CMGC_DYRK_HIPK_HIPK2_ST	Q9H2X6	HIPK2	Q9H2X6	HIPK2	S294	K289E	289	Missense	distal	-5	no	105.124	106.966	EPSD	ICGC;COSMIC	98.777	Up-regulation
CMGC_DYRK_HIPK_HIPK2_ST	Q9H2X6	HIPK2	Q9H2X6	HIPK2	S441	P442L	442	Missense	proximal	1	no	106.073	-14.212	EPSD	ICGC;COSMIC	98.777	Loss
CMGC_DYRK_HIPK_HIPK2_ST	Q9H2X6	HIPK2	Q9H2X6	HIPK2	S441	R437S	437	Missense	distal	-4	no	106.073	106.199	EPSD	ICGC;COSMIC	98.777	Up-regulation
CMGC_DYRK_HIPK_HIPK2_ST	Q9H2X6	HIPK2	Q9H2X6	HIPK2	T566	T570M	570	Missense	distal	4	no	101.793	101.602	EPSD	ICGC;COSMIC	98.777	Down-regulation
CMGC_DYRK_HIPK_HIPK2_ST	Q9H2X6	HIPK2	Q9H2X6	HIPK2	T566	T560K	560	Missense	distal	-6	no	101.793	102.150	EPSD	ICGC	98.777	Up-regulation
CMGC_DYRK_HIPK_HIPK2_ST	Q9H2X6	HIPK2	Q9H2X6	HIPK2	T566	T570A	570	Missense	distal	4	no	101.793	102.550	EPSD	ICGC;COSMIC	98.777	Up-regulation
CMGC_DYRK_HIPK_HIPK2_ST	Q9H2X6	HIPK2	Q9H2X6	HIPK2	S668	A667D	667	Missense	proximal	-1	no	102.145	102.255	EPSD	ICGC;COSMIC	98.777	Up-regulation
CMGC_DYRK_HIPK_HIPK2_ST	Q9H2X6	HIPK2	Q9H2X6	HIPK2	S668	A667S	667	Missense	proximal	-1	no	102.145	103.219	EPSD	ICGC;COSMIC	98.777	Up-regulation
CMGC_DYRK_HIPK_HIPK2_ST	Q9H2X6	HIPK2	Q9H2X6	HIPK2	T838	R841H	841	Missense	distal	3	no	99.480	98.992	EPSD	ICGC;COSMIC	98.777	Down-regulation
CMGC_DYRK_HIPK_HIPK2_ST	Q9H2X6	HIPK2	Q9H2X6	HIPK2	T838	P839T	839	Missense	proximal	1	no	99.480	-51.856	EPSD	ICGC	98.777	Loss
CMGC_DYRK_HIPK_HIPK2_ST	Q9H2X6	HIPK2	Q9H2X6	HIPK2	T838	M844I	844	Missense	distal	6	no	99.480	99.689	EPSD	ICGC;COSMIC	98.777	Up-regulation
CMGC_DYRK_HIPK_HIPK2_ST	Q9H2X6	HIPK2	Q9H2X6	HIPK2	T880	S882G	882	Missense	proximal	2	no	121.162	120.194	PhosphoSitePlus;EPSD	ICGC;COSMIC	98.777	Down-regulation
CMGC_DYRK_HIPK_HIPK2_ST	Q9H2X6	HIPK2	Q9H2X6	HIPK2	T880	P878T	878	Missense	proximal	-2	no	121.162	120.875	PhosphoSitePlus;EPSD	ICGC	98.777	Down-regulation
CMGC_DYRK_HIPK_HIPK2_ST	Q9H2X6	HIPK2	Q9H2X6	HIPK2	T880	P878S	878	Missense	proximal	-2	no	121.162	121.237	PhosphoSitePlus;EPSD	ICGC	98.777	Up-regulation
CMGC_DYRK_HIPK_HIPK2_ST	Q9H2X6	HIPK2	Q9H2X6	HIPK2	T880	V887A	887	Missense	distal	7	no	121.162	121.489	PhosphoSitePlus;EPSD	ICGC	98.777	Up-regulation
CMGC_DYRK_HIPK_HIPK2_ST	Q9H2X6	HIPK2	Q9H2X6	HIPK2	S882	S882G	882	Missense	central	0	yes	118.885	0.000	EPSD;PhosphoSitePlus	ICGC;COSMIC	98.777	Loss
CMGC_DYRK_HIPK_HIPK2_ST	Q9H2X6	HIPK2	Q9H2X6	HIPK2	S882	P878T	878	Missense	distal	-4	no	118.885	118.754	EPSD;PhosphoSitePlus	ICGC	98.777	Down-regulation
CMGC_DYRK_HIPK_HIPK2_ST	Q9H2X6	HIPK2	Q9H2X6	HIPK2	S882	P878S	878	Missense	distal	-4	no	118.885	118.751	EPSD;PhosphoSitePlus	ICGC	98.777	Down-regulation
CMGC_DYRK_HIPK_HIPK2_ST	Q9H2X6	HIPK2	Q9H2X6	HIPK2	S882	V887A	887	Missense	distal	5	no	118.885	118.787	EPSD;PhosphoSitePlus	ICGC	98.777	Down-regulation
CMGC_DYRK_HIPK_HIPK2_ST	Q9H2X6	HIPK2	Q9H2X6	HIPK2	S934	R941C	941	Missense	distal	7	no	105.408	105.087	EPSD	ICGC;GDSC	98.777	Down-regulation
CMGC_DYRK_HIPK_HIPK2_ST	Q9H2X6	HIPK2	Q9H2X6	HIPK2	S934	N932Y	932	Missense	proximal	-2	no	105.408	105.173	EPSD	ICGC;COSMIC	98.777	Down-regulation
CMGC_DYRK_HIPK_HIPK2_ST	Q9H2X6	HIPK2	Q9H2X6	HIPK2	S1014	G1011S	1011	Missense	distal	-3	no	103.648	103.560	EPSD	ICGC;COSMIC	98.777	Down-regulation
CMGC_DYRK_HIPK_HIPK2_ST	Q9H2X6	HIPK2	Q9H2X6	HIPK2	S1014	T1009N	1009	Missense	distal	-5	no	103.648	105.149	EPSD	ICGC	98.777	Up-regulation
CMGC_DYRK_HIPK_HIPK2_ST	Q9H2X6	HIPK2	Q9H2X6	HIPK2	S1018	G1011S	1011	Missense	distal	-7	no	103.681	103.353	EPSD	ICGC;COSMIC	98.777	Down-regulation
CMGC_DYRK_HIPK_HIPK2_ST	Q9H2X6	HIPK2	Q9H2X6	HIPK2	T1114	V1121G	1121	Missense	distal	7	no	99.866	99.897	EPSD	ICGC;COSMIC	98.777	Up-regulation
CMGC_DYRK_HIPK_HIPK2_ST	Q9H2X6	HIPK2	Q9H2X6	HIPK2	T1114	P1108L	1108	Missense	distal	-6	no	99.866	99.731	EPSD	ICGC;COSMIC	98.777	Down-regulation
CMGC_DYRK_HIPK_HIPK2_ST	Q9H2X6	HIPK2	Q9H2X6	HIPK2	T1114	G1112C	1112	Missense	proximal	-2	no	99.866	98.818	EPSD	ICGC;COSMIC	98.777	Down-regulation
CMGC_DYRK_HIPK_HIPK2_ST	P46527	CDKN1B	Q9H2X6	HIPK2	S10	N8K	8	Missense	proximal	-2	no	103.610	103.881	PhosphoSitePlus	ICGC;COSMIC	98.777	Up-regulation
CMGC_DYRK_HIPK_HIPK2_ST	P46527	CDKN1B	Q9H2X6	HIPK2	S110	V109G	109	Missense	proximal	-1	no	108.233	109.076	EPSD	ICGC;COSMIC	98.777	Up-regulation
CMGC_DYRK_HIPK_HIPK2_ST	P46527	CDKN1B	Q9H2X6	HIPK2	S112	V109G	109	Missense	distal	-3	no	103.876	103.523	EPSD	ICGC;COSMIC	98.777	Down-regulation
CMGC_DYRK_HIPK_HIPK2_ST	P46527	CDKN1B	Q9H2X6	HIPK2	T142	S138W	138	Missense	distal	-4	no	108.563	108.007	EPSD	ICGC	98.777	Down-regulation
CMGC_DYRK_HIPK_HIPK2_ST	P46527	CDKN1B	Q9H2X6	HIPK2	S178	V184M	184	Missense	distal	6	no	99.666	99.640	EPSD	ICGC;COSMIC	98.777	Down-regulation
CMGC_DYRK_HIPK_HIPK2_ST	P46527	CDKN1B	Q9H2X6	HIPK2	S178	G182C	182	Missense	distal	4	no	99.666	90.374	EPSD	ICGC	98.777	Loss
CMGC_DYRK_HIPK_HIPK2_ST	P46527	CDKN1B	Q9H2X6	HIPK2	S178	G177V	177	Missense	proximal	-1	no	99.666	98.823	EPSD	ICGC	98.777	Down-regulation
CMGC_DYRK_HIPK_HIPK2_ST	P46527	CDKN1B	Q9H2X6	HIPK2	S178	S178F	178	Missense	central	0	yes	99.666	0.000	EPSD	ICGC;COSMIC	98.777	Loss
CMGC_DYRK_HIPK_HIPK2_ST	O00257	CBX4	Q9H2X6	HIPK2	S291	A298S	298	Missense	distal	7	no	111.295	111.426	EPSD	ICGC	98.777	Up-regulation
CMGC_DYRK_HIPK_HIPK2_ST	O00257	CBX4	Q9H2X6	HIPK2	S291	R297W	297	Missense	distal	6	no	111.295	110.657	EPSD	ICGC	98.777	Down-regulation
CMGC_DYRK_HIPK_HIPK2_ST	O00257	CBX4	Q9H2X6	HIPK2	S291	S291P	291	Missense	central	0	yes	111.295	0.000	EPSD	ICGC;COSMIC	98.777	Loss
CMGC_DYRK_HIPK_HIPK2_ST	O00257	CBX4	Q9H2X6	HIPK2	S333	E329D	329	Missense	distal	-4	no	103.909	103.894	EPSD	ICGC	98.777	Down-regulation
CMGC_DYRK_HIPK_HIPK2_ST	O00257	CBX4	Q9H2X6	HIPK2	S345	K352N	352	Missense	distal	7	no	104.813	104.711	EPSD	ICGC;COSMIC	98.777	Down-regulation
CMGC_DYRK_HIPK_HIPK2_ST	O00257	CBX4	Q9H2X6	HIPK2	S345	G344C	344	Missense	proximal	-1	no	104.813	102.046	EPSD	ICGC;COSMIC	98.777	Down-regulation
CMGC_DYRK_HIPK_HIPK2_ST	O00257	CBX4	Q9H2X6	HIPK2	S349	K352N	352	Missense	distal	3	no	110.746	110.659	EPSD	ICGC;COSMIC	98.777	Down-regulation
CMGC_DYRK_HIPK_HIPK2_ST	O00257	CBX4	Q9H2X6	HIPK2	S349	G344C	344	Missense	distal	-5	no	110.746	101.649	EPSD	ICGC;COSMIC	98.777	Down-regulation
CMGC_DYRK_HIPK_HIPK2_ST	O00257	CBX4	Q9H2X6	HIPK2	T435	T435N	435	Missense	central	0	yes	102.901	0.000	EPSD	ICGC	98.777	Loss
CMGC_DYRK_HIPK_HIPK2_ST	O00257	CBX4	Q9H2X6	HIPK2	T435	I433T	433	Missense	proximal	-2	no	102.901	102.691	EPSD	ICGC;COSMIC	98.777	Down-regulation
CMGC_DYRK_HIPK_HIPK2_ST	O00257	CBX4	Q9H2X6	HIPK2	T435	S442I	442	Missense	distal	7	no	102.901	102.589	EPSD	ICGC;COSMIC	98.777	Down-regulation
CMGC_DYRK_HIPK_HIPK2_ST	O00257	CBX4	Q9H2X6	HIPK2	S442	T435N	435	Missense	distal	-7	no	109.811	110.665	EPSD	ICGC	98.777	Up-regulation
CMGC_DYRK_HIPK_HIPK2_ST	O00257	CBX4	Q9H2X6	HIPK2	S442	S442I	442	Missense	central	0	yes	109.811	0.000	EPSD	ICGC;COSMIC	98.777	Loss
CMGC_DYRK_HIPK_HIPK2_ST	O00257	CBX4	Q9H2X6	HIPK2	T480	P487L	487	Missense	distal	7	no	99.429	99.251	EPSD	ICGC	98.777	Down-regulation
CMGC_DYRK_HIPK_HIPK2_ST	O00257	CBX4	Q9H2X6	HIPK2	T480	T480M	480	Missense	central	0	yes	99.429	0.000	EPSD	ICGC;COSMIC	98.777	Loss
CMGC_DYRK_HIPK_HIPK2_ST	O00257	CBX4	Q9H2X6	HIPK2	T497	E496Q	496	Missense	proximal	-1	no	120.888	120.594	PhosphoSitePlus	ICGC;COSMIC	98.777	Down-regulation
CMGC_DYRK_HIPK_HIPK2_ST	O43255	SIAH2	Q9H2X6	HIPK2	T254	T254N	254	Missense	central	0	yes	100.699	0.000	EPSD	ICGC;COSMIC	98.777	Loss
CMGC_DYRK_HIPK_HIPK2_ST	Q9H3D4	TP63	Q9H2X6	HIPK2	S160	S154F	154	Missense	distal	-6	no	104.093	103.894	EPSD	ICGC;COSMIC;GDSC;CCLE	98.777	Down-regulation
CMGC_DYRK_HIPK_HIPK2_ST	Q9H3D4	TP63	Q9H2X6	HIPK2	S160	P166S	166	Missense	distal	6	no	104.093	104.004	EPSD	ICGC;COSMIC	98.777	Down-regulation
CMGC_DYRK_HIPK_HIPK2_ST	Q9H3D4	TP63	Q9H2X6	HIPK2	S160	P161A	161	Missense	proximal	1	no	104.093	-24.431	EPSD	ICGC	98.777	Loss
CMGC_DYRK_HIPK_HIPK2_ST	Q9H3D4	TP63	Q9H2X6	HIPK2	S160	P161Q	161	Missense	proximal	1	no	104.093	51.997	EPSD	ICGC;COSMIC	98.777	Loss
CMGC_DYRK_HIPK_HIPK2_ST	Q9H3D4	TP63	Q9H2X6	HIPK2	S160	S162L	162	Missense	proximal	2	no	104.093	102.579	EPSD	ICGC;COSMIC;GDSC;CCLE	98.777	Down-regulation
CMGC_DYRK_HIPK_HIPK2_ST	Q9H3D4	TP63	Q9H2X6	HIPK2	S160	I165T	165	Missense	distal	5	no	104.093	104.186	EPSD	ICGC;COSMIC	98.777	Up-regulation
CMGC_DYRK_HIPK_HIPK2_ST	Q9H3D4	TP63	Q9H2X6	HIPK2	S160	D157N	157	Missense	distal	-3	no	104.093	104.157	EPSD	ICGC;COSMIC	98.777	Up-regulation
CMGC_DYRK_HIPK_HIPK2_ST	Q9H3D4	TP63	Q9H2X6	HIPK2	S162	P166S	166	Missense	distal	4	no	117.768	118.900	EPSD	ICGC;COSMIC	98.777	Up-regulation
CMGC_DYRK_HIPK_HIPK2_ST	Q9H3D4	TP63	Q9H2X6	HIPK2	S162	P161A	161	Missense	proximal	-1	no	117.768	117.010	EPSD	ICGC	98.777	Down-regulation
CMGC_DYRK_HIPK_HIPK2_ST	Q9H3D4	TP63	Q9H2X6	HIPK2	S162	P161Q	161	Missense	proximal	-1	no	117.768	117.595	EPSD	ICGC;COSMIC	98.777	Down-regulation
CMGC_DYRK_HIPK_HIPK2_ST	Q9H3D4	TP63	Q9H2X6	HIPK2	S162	S162L	162	Missense	central	0	yes	117.768	0.000	EPSD	ICGC;COSMIC;GDSC;CCLE	98.777	Loss
CMGC_DYRK_HIPK_HIPK2_ST	Q9H3D4	TP63	Q9H2X6	HIPK2	S162	I165T	165	Missense	distal	3	no	117.768	117.316	EPSD	ICGC;COSMIC	98.777	Down-regulation
CMGC_DYRK_HIPK_HIPK2_ST	Q9H3D4	TP63	Q9H2X6	HIPK2	S162	D157N	157	Missense	distal	-5	no	117.768	114.172	EPSD	ICGC;COSMIC	98.777	Down-regulation
CMGC_DYRK_HIPK_HIPK2_ST	Q9H3D4	TP63	Q9H2X6	HIPK2	S395	R393C	393	Missense	proximal	-2	no	106.730	106.031	EPSD	ICGC;COSMIC	98.777	Down-regulation
CMGC_DYRK_HIPK_HIPK2_ST	Q9H3D4	TP63	Q9H2X6	HIPK2	S395	R393S	393	Missense	proximal	-2	no	106.730	107.052	EPSD	ICGC	98.777	Up-regulation
CMGC_DYRK_HIPK_HIPK2_ST	Q9H3D4	TP63	Q9H2X6	HIPK2	S395	R393H	393	Missense	proximal	-2	no	106.730	106.323	EPSD	ICGC;COSMIC	98.777	Down-regulation
CMGC_DYRK_HIPK_HIPK2_ST	Q9H3D4	TP63	Q9H2X6	HIPK2	S395	T388P	388	Missense	distal	-7	no	106.730	108.037	EPSD	ICGC;COSMIC	98.777	Up-regulation
CMGC_DYRK_HIPK_HIPK2_ST	P17676	CEBPB	Q9H2X6	HIPK2	S76	I73M	73	Missense	distal	-3	no	104.351	104.443	EPSD	ICGC	98.777	Up-regulation
CMGC_DYRK_HIPK_HIPK2_ST	P17676	CEBPB	Q9H2X6	HIPK2	S141	L142P	142	Missense	proximal	1	no	-19.664	100.621	EPSD	ICGC;COSMIC	98.777	Gain
CMGC_DYRK_HIPK_HIPK2_ST	P17676	CEBPB	Q9H2X6	HIPK2	S218	L224I	224	Missense	distal	6	no	102.207	102.341	EPSD	ICGC;COSMIC	98.777	Up-regulation
CMGC_DYRK_HIPK_HIPK2_ST	P17676	CEBPB	Q9H2X6	HIPK2	S221	L224I	224	Missense	distal	3	no	102.331	102.542	EPSD	ICGC;COSMIC	98.777	Up-regulation
CMGC_DYRK_HIPK_HIPK2_ST	P17676	CEBPB	Q9H2X6	HIPK2	S229	L224I	224	Missense	distal	-5	no	95.256	99.623	EPSD	ICGC;COSMIC	98.777	Gain
CMGC_DYRK_HIPK_HIPK2_ST	P17676	CEBPB	Q9H2X6	HIPK2	S230	L224I	224	Missense	distal	-6	no	101.352	101.487	EPSD	ICGC;COSMIC	98.777	Up-regulation
CMGC_DYRK_HIPK_HIPK2_ST	P17676	CEBPB	Q9H2X6	HIPK2	S231	L224I	224	Missense	distal	-7	no	105.286	105.478	EPSD	ICGC;COSMIC	98.777	Up-regulation
CMGC_DYRK_HIPK_HIPK2_ST	P17676	CEBPB	Q9H2X6	HIPK2	S231	P238H	238	Missense	distal	7	no	105.286	104.625	EPSD	ICGC;COSMIC	98.777	Down-regulation
CMGC_DYRK_HIPK_HIPK2_ST	P17676	CEBPB	Q9H2X6	HIPK2	T235	P238H	238	Missense	distal	3	no	117.638	117.072	PhosphoSitePlus	ICGC;COSMIC	98.777	Down-regulation
CMGC_DYRK_HIPK_HIPK2_ST	P17676	CEBPB	Q9H2X6	HIPK2	S237	P238H	238	Missense	proximal	1	no	107.804	-4.250	EPSD	ICGC;COSMIC	98.777	Loss
Atypical_PIKK_FRAP_MTOR_ST	Q8N122	RPTOR	P42345	MTOR	S696	T699M	699	Missense	distal	3	no	11.129	9.156	EPSD	ICGC;COSMIC	6.822	Down-regulation
Atypical_PIKK_FRAP_MTOR_ST	Q8N122	RPTOR	P42345	MTOR	S704	T699M	699	Missense	distal	-5	no	10.835	10.823	EPSD	ICGC;COSMIC	6.822	Down-regulation
Atypical_PIKK_FRAP_MTOR_ST	Q8N122	RPTOR	P42345	MTOR	T706	T699M	699	Missense	distal	-7	no	8.436	7.797	EPSD	ICGC;COSMIC	6.822	Down-regulation
Atypical_PIKK_FRAP_MTOR_ST	Q8N122	RPTOR	P42345	MTOR	S882	S887N	887	Missense	distal	5	no	7.315	8.797	EPSD	ICGC;COSMIC	6.822	Up-regulation
Atypical_PIKK_FRAP_MTOR_ST	Q13541	EIF4EBP1	P42345	MTOR	S35	G40V	40	Missense	distal	5	no	9.948	10.407	EPSD	ICGC;COSMIC	6.822	Up-regulation
Atypical_PIKK_FRAP_MTOR_ST	Q13541	EIF4EBP1	P42345	MTOR	S35	S35I	35	Missense	central	0	yes	9.948	0.000	EPSD	ICGC	6.822	Loss
Atypical_PIKK_FRAP_MTOR_ST	Q13541	EIF4EBP1	P42345	MTOR	S35	T41S	41	Missense	distal	6	no	9.948	10.862	EPSD	ICGC;COSMIC	6.822	Up-regulation
Atypical_PIKK_FRAP_MTOR_ST	Q13541	EIF4EBP1	P42345	MTOR	T36	G40V	40	Missense	distal	4	no	8.463	8.674	EPSD	ICGC;COSMIC	6.822	Up-regulation
Atypical_PIKK_FRAP_MTOR_ST	Q13541	EIF4EBP1	P42345	MTOR	T36	S35I	35	Missense	proximal	-1	no	8.463	8.227	EPSD	ICGC	6.822	Down-regulation
Atypical_PIKK_FRAP_MTOR_ST	Q13541	EIF4EBP1	P42345	MTOR	T36	T41S	41	Missense	distal	5	no	8.463	8.860	EPSD	ICGC;COSMIC	6.822	Up-regulation
Atypical_PIKK_FRAP_MTOR_ST	Q13541	EIF4EBP1	P42345	MTOR	T37	G40V	40	Missense	distal	3	no	14.304	12.281	EPSD;PhosphoSitePlus	ICGC;COSMIC	6.822	Down-regulation
Atypical_PIKK_FRAP_MTOR_ST	Q13541	EIF4EBP1	P42345	MTOR	T37	S35I	35	Missense	proximal	-2	no	14.304	13.865	EPSD;PhosphoSitePlus	ICGC	6.822	Down-regulation
Atypical_PIKK_FRAP_MTOR_ST	Q13541	EIF4EBP1	P42345	MTOR	T37	T41S	41	Missense	distal	4	no	14.304	14.237	EPSD;PhosphoSitePlus	ICGC;COSMIC	6.822	Down-regulation
Atypical_PIKK_FRAP_MTOR_ST	Q13541	EIF4EBP1	P42345	MTOR	T41	G40V	40	Missense	proximal	-1	no	8.048	7.977	EPSD;PhosphoSitePlus	ICGC;COSMIC	6.822	Down-regulation
Atypical_PIKK_FRAP_MTOR_ST	Q13541	EIF4EBP1	P42345	MTOR	T41	S35I	35	Missense	distal	-6	no	8.048	7.489	EPSD;PhosphoSitePlus	ICGC	6.822	Down-regulation
Atypical_PIKK_FRAP_MTOR_ST	Q13541	EIF4EBP1	P42345	MTOR	S44	G40V	40	Missense	distal	-4	no	8.010	7.894	EPSD;PhosphoSitePlus	ICGC;COSMIC	6.822	Down-regulation
Atypical_PIKK_FRAP_MTOR_ST	Q13541	EIF4EBP1	P42345	MTOR	S44	T41S	41	Missense	distal	-3	no	8.010	8.449	EPSD;PhosphoSitePlus	ICGC;COSMIC	6.822	Up-regulation
Atypical_PIKK_FRAP_MTOR_ST	Q13541	EIF4EBP1	P42345	MTOR	T45	G40V	40	Missense	distal	-5	no	6.892	6.762	EPSD	ICGC;COSMIC	6.822	Loss
Atypical_PIKK_FRAP_MTOR_ST	Q13541	EIF4EBP1	P42345	MTOR	T45	T41S	41	Missense	distal	-4	no	6.892	7.394	EPSD	ICGC;COSMIC	6.822	Up-regulation
Atypical_PIKK_FRAP_MTOR_ST	Q13541	EIF4EBP1	P42345	MTOR	T46	G40V	40	Missense	distal	-6	no	12.968	12.224	EPSD;PhosphoSitePlus	ICGC;COSMIC	6.822	Down-regulation
Atypical_PIKK_FRAP_MTOR_ST	Q13541	EIF4EBP1	P42345	MTOR	T46	T41S	41	Missense	distal	-5	no	12.968	12.962	EPSD;PhosphoSitePlus	ICGC;COSMIC	6.822	Down-regulation
Atypical_PIKK_FRAP_MTOR_ST	Q13541	EIF4EBP1	P42345	MTOR	S65	P71A	71	Missense	distal	6	no	9.149	8.528	PhosphoSitePlus;EPSD	ICGC;COSMIC	6.822	Down-regulation
Atypical_PIKK_FRAP_MTOR_ST	Q13541	EIF4EBP1	P42345	MTOR	S65	P71H	71	Missense	distal	6	no	9.149	7.673	PhosphoSitePlus;EPSD	ICGC;COSMIC	6.822	Down-regulation
Atypical_PIKK_FRAP_MTOR_ST	Q13541	EIF4EBP1	P42345	MTOR	T70	P71A	71	Missense	proximal	1	no	9.629	0.745	EPSD;PhosphoSitePlus	ICGC;COSMIC	6.822	Loss
Atypical_PIKK_FRAP_MTOR_ST	Q13541	EIF4EBP1	P42345	MTOR	T70	P71H	71	Missense	proximal	1	no	9.629	-17.562	EPSD;PhosphoSitePlus	ICGC;COSMIC	6.822	Loss
Atypical_PIKK_FRAP_MTOR_ST	Q13541	EIF4EBP1	P42345	MTOR	S101	S94I	94	Missense	distal	-7	no	15.851	14.845	EPSD	ICGC	6.822	Down-regulation
Atypical_PIKK_FRAP_MTOR_ST	Q13541	EIF4EBP1	P42345	MTOR	S101	R106Q	106	Missense	distal	5	no	15.851	15.044	EPSD	ICGC;COSMIC	6.822	Down-regulation
Atypical_PIKK_FRAP_MTOR_ST	Q13541	EIF4EBP1	P42345	MTOR	S101	G108C	108	Missense	distal	7	no	15.851	16.689	EPSD	ICGC;COSMIC	6.822	Up-regulation
Atypical_PIKK_FRAP_MTOR_ST	Q13541	EIF4EBP1	P42345	MTOR	S101	A107T	107	Missense	distal	6	no	15.851	15.588	EPSD	ICGC;COSMIC	6.822	Down-regulation
Atypical_PIKK_FRAP_MTOR_ST	Q13541	EIF4EBP1	P42345	MTOR	S101	D104Y	104	Missense	distal	3	no	15.851	15.385	EPSD	ICGC;COSMIC	6.822	Down-regulation
Atypical_PIKK_FRAP_MTOR_ST	Q13541	EIF4EBP1	P42345	MTOR	S101	H97Q	97	Missense	distal	-4	no	15.851	16.547	EPSD	ICGC;COSMIC	6.822	Up-regulation
Atypical_PIKK_FRAP_MTOR_ST	Q13541	EIF4EBP1	P42345	MTOR	S101	S101C	101	Missense	central	0	yes	15.851	0.000	EPSD	ICGC;COSMIC	6.822	Loss
Atypical_PIKK_FRAP_MTOR_ST	O75179	ANKRD17	P42345	MTOR	S19	V26L	26	Missense	distal	7	no	13.560	14.024	EPSD	ICGC	6.822	Up-regulation
Atypical_PIKK_FRAP_MTOR_ST	O75179	ANKRD17	P42345	MTOR	S19	T12M	12	Missense	distal	-7	no	13.560	12.921	EPSD	ICGC;COSMIC	6.822	Down-regulation
Atypical_PIKK_FRAP_MTOR_ST	O75179	ANKRD17	P42345	MTOR	S47	R46H	46	Missense	proximal	-1	no	10.021	10.062	EPSD	ICGC;COSMIC	6.822	Up-regulation
Atypical_PIKK_FRAP_MTOR_ST	O75179	ANKRD17	P42345	MTOR	S47	M54T	54	Missense	distal	7	no	10.021	8.935	EPSD	ICGC;COSMIC	6.822	Down-regulation
Atypical_PIKK_FRAP_MTOR_ST	O75179	ANKRD17	P42345	MTOR	S49	R46H	46	Missense	distal	-3	no	7.964	7.217	EPSD	ICGC;COSMIC	6.822	Down-regulation
Atypical_PIKK_FRAP_MTOR_ST	O75179	ANKRD17	P42345	MTOR	S49	M54T	54	Missense	distal	5	no	7.964	7.701	EPSD	ICGC;COSMIC	6.822	Down-regulation
Atypical_PIKK_FRAP_MTOR_ST	O75179	ANKRD17	P42345	MTOR	S50	R46H	46	Missense	distal	-4	no	12.246	11.053	EPSD	ICGC;COSMIC	6.822	Down-regulation
Atypical_PIKK_FRAP_MTOR_ST	O75179	ANKRD17	P42345	MTOR	S50	M54T	54	Missense	distal	4	no	12.246	12.460	EPSD	ICGC;COSMIC	6.822	Up-regulation
Atypical_PIKK_FRAP_MTOR_ST	O75179	ANKRD17	P42345	MTOR	S113	E120K	120	Missense	distal	7	no	6.776	6.873	EPSD	ICGC	6.822	Gain
Atypical_PIKK_FRAP_MTOR_ST	O75179	ANKRD17	P42345	MTOR	S469	A475D	475	Missense	distal	6	no	9.636	10.003	EPSD	ICGC;COSMIC	6.822	Up-regulation
Atypical_PIKK_FRAP_MTOR_ST	O75179	ANKRD17	P42345	MTOR	S469	F467S	467	Missense	proximal	-2	no	9.636	9.457	EPSD	ICGC;COSMIC	6.822	Down-regulation
Atypical_PIKK_FRAP_MTOR_ST	O75179	ANKRD17	P42345	MTOR	S1607	S1603F	1603	Missense	distal	-4	no	7.673	7.698	EPSD	ICGC;GDSC;CCLE	6.822	Up-regulation
Atypical_PIKK_FRAP_MTOR_ST	O75179	ANKRD17	P42345	MTOR	S1672	A1671D	1671	Missense	proximal	-1	no	7.344	7.288	EPSD	ICGC	6.822	Down-regulation
Atypical_PIKK_FRAP_MTOR_ST	O75179	ANKRD17	P42345	MTOR	S1672	G1669D	1669	Missense	distal	-3	no	7.344	7.097	EPSD	ICGC;COSMIC;GDSC;CCLE	6.822	Down-regulation
Atypical_PIKK_FRAP_MTOR_ST	O75179	ANKRD17	P42345	MTOR	S1672	L1675S	1675	Missense	distal	3	no	7.344	9.612	EPSD	ICGC;COSMIC	6.822	Up-regulation
Atypical_PIKK_FRAP_MTOR_ST	O75179	ANKRD17	P42345	MTOR	S1696	S1700T	1700	Missense	distal	4	no	9.119	9.186	EPSD	ICGC	6.822	Up-regulation
Atypical_PIKK_FRAP_MTOR_ST	O75179	ANKRD17	P42345	MTOR	T2279	S2275Y	2275	Missense	distal	-4	no	12.302	11.672	EPSD	ICGC;COSMIC	6.822	Down-regulation
Atypical_PIKK_FRAP_MTOR_ST	Q9HB90	RRAGC	P42345	MTOR	T10	G17D	17	Missense	distal	7	no	8.086	8.263	EPSD	ICGC	6.822	Up-regulation
Atypical_PIKK_FRAP_MTOR_ST	Q9HB90	RRAGC	P42345	MTOR	T10	T10K	10	Missense	central	0	yes	8.086	0.000	EPSD	ICGC	6.822	Loss
Atypical_PIKK_FRAP_MTOR_ST	Q9HB90	RRAGC	P42345	MTOR	T10	L3V	3	Missense	distal	-7	no	8.086	7.927	EPSD	ICGC	6.822	Down-regulation
Atypical_PIKK_FRAP_MTOR_ST	Q9HB90	RRAGC	P42345	MTOR	S15	G17D	17	Missense	proximal	2	no	7.982	8.018	EPSD	ICGC	6.822	Up-regulation
Atypical_PIKK_FRAP_MTOR_ST	Q9HB90	RRAGC	P42345	MTOR	S15	T10K	10	Missense	distal	-5	no	7.982	7.961	EPSD	ICGC	6.822	Down-regulation
Atypical_PIKK_FRAP_MTOR_ST	Q9HB90	RRAGC	P42345	MTOR	S86	T90N	90	Missense	distal	4	no	9.375	8.834	EPSD	ICGC;COSMIC	6.822	Down-regulation
Atypical_PIKK_FRAP_MTOR_ST	Q9HB90	RRAGC	P42345	MTOR	S86	V80G	80	Missense	distal	-6	no	9.375	10.119	EPSD	ICGC;COSMIC	6.822	Up-regulation
Atypical_PIKK_FRAP_MTOR_ST	Q9HB90	RRAGC	P42345	MTOR	S86	V80A	80	Missense	distal	-6	no	9.375	9.659	EPSD	ICGC;COSMIC	6.822	Up-regulation
Atypical_PIKK_FRAP_MTOR_ST	Q9HB90	RRAGC	P42345	MTOR	S95	N97K	97	Missense	proximal	2	no	5.677	7.012	EPSD	ICGC	6.822	Gain
Atypical_PIKK_FRAP_MTOR_ST	Q9HB90	RRAGC	P42345	MTOR	S382	L386V	386	Missense	distal	4	no	7.160	7.488	EPSD	ICGC;COSMIC	6.822	Up-regulation
Atypical_PIKK_FRAP_MTOR_ST	Q9HB90	RRAGC	P42345	MTOR	S382	H379N	379	Missense	distal	-3	no	7.160	8.111	EPSD	ICGC	6.822	Up-regulation
Atypical_PIKK_FRAP_MTOR_ST	Q9HB90	RRAGC	P42345	MTOR	T394	N397K	397	Missense	distal	3	no	8.997	8.162	EPSD;PhosphoSitePlus	ICGC	6.822	Down-regulation
Atypical_PIKK_FRAP_MTOR_ST	O00418	EEF2K	P42345	MTOR	S18	H23R	23	Missense	distal	5	no	13.463	13.158	EPSD	ICGC;COSMIC	6.822	Down-regulation
Atypical_PIKK_FRAP_MTOR_ST	O00418	EEF2K	P42345	MTOR	S18	A21S	21	Missense	distal	3	no	13.463	12.408	EPSD	ICGC;COSMIC	6.822	Down-regulation
Atypical_PIKK_FRAP_MTOR_ST	O00418	EEF2K	P42345	MTOR	S31	D32N	32	Missense	proximal	1	no	7.324	8.670	EPSD	ICGC;COSMIC	6.822	Up-regulation
Atypical_PIKK_FRAP_MTOR_ST	O00418	EEF2K	P42345	MTOR	S31	G29W	29	Missense	proximal	-2	no	7.324	6.168	EPSD	ICGC	6.822	Loss
Atypical_PIKK_FRAP_MTOR_ST	O00418	EEF2K	P42345	MTOR	S31	E34D	34	Missense	distal	3	no	7.324	6.397	EPSD	ICGC;COSMIC	6.822	Loss
Atypical_PIKK_FRAP_MTOR_ST	O00418	EEF2K	P42345	MTOR	S71	P75A	75	Missense	distal	4	no	8.697	8.479	EPSD	ICGC;COSMIC	6.822	Down-regulation
Atypical_PIKK_FRAP_MTOR_ST	O00418	EEF2K	P42345	MTOR	S71	P75L	75	Missense	distal	4	no	8.697	8.313	EPSD	ICGC;COSMIC	6.822	Down-regulation
Atypical_PIKK_FRAP_MTOR_ST	O00418	EEF2K	P42345	MTOR	S71	S71F	71	Missense	central	0	yes	8.697	0.000	EPSD	ICGC;COSMIC	6.822	Loss
Atypical_PIKK_FRAP_MTOR_ST	O00418	EEF2K	P42345	MTOR	S71	S66R	66	Missense	distal	-5	no	8.697	8.839	EPSD	ICGC	6.822	Up-regulation
Atypical_PIKK_FRAP_MTOR_ST	O00418	EEF2K	P42345	MTOR	S72	P75A	75	Missense	distal	3	no	9.703	10.772	PhosphoSitePlus;EPSD	ICGC;COSMIC	6.822	Up-regulation
Atypical_PIKK_FRAP_MTOR_ST	O00418	EEF2K	P42345	MTOR	S72	P75L	75	Missense	distal	3	no	9.703	7.449	PhosphoSitePlus;EPSD	ICGC;COSMIC	6.822	Down-regulation
Atypical_PIKK_FRAP_MTOR_ST	O00418	EEF2K	P42345	MTOR	S72	S71F	71	Missense	proximal	-1	no	9.703	9.519	PhosphoSitePlus;EPSD	ICGC;COSMIC	6.822	Down-regulation
Atypical_PIKK_FRAP_MTOR_ST	O00418	EEF2K	P42345	MTOR	S72	F79L	79	Missense	distal	7	no	9.703	10.100	PhosphoSitePlus;EPSD	ICGC	6.822	Up-regulation
Atypical_PIKK_FRAP_MTOR_ST	O00418	EEF2K	P42345	MTOR	S72	S66R	66	Missense	distal	-6	no	9.703	9.810	PhosphoSitePlus;EPSD	ICGC	6.822	Up-regulation
Atypical_PIKK_FRAP_MTOR_ST	O00418	EEF2K	P42345	MTOR	S74	P75A	75	Missense	proximal	1	no	12.409	3.526	EPSD;PhosphoSitePlus	ICGC;COSMIC	6.822	Loss
Atypical_PIKK_FRAP_MTOR_ST	O00418	EEF2K	P42345	MTOR	S74	P75L	75	Missense	proximal	1	no	12.409	6.440	EPSD;PhosphoSitePlus	ICGC;COSMIC	6.822	Loss
Atypical_PIKK_FRAP_MTOR_ST	O00418	EEF2K	P42345	MTOR	S74	S71F	71	Missense	distal	-3	no	12.409	12.480	EPSD;PhosphoSitePlus	ICGC;COSMIC	6.822	Up-regulation
Atypical_PIKK_FRAP_MTOR_ST	O00418	EEF2K	P42345	MTOR	S74	F79L	79	Missense	distal	5	no	12.409	13.309	EPSD;PhosphoSitePlus	ICGC	6.822	Up-regulation
Atypical_PIKK_FRAP_MTOR_ST	O00418	EEF2K	P42345	MTOR	S470	D471Y	471	Missense	proximal	1	no	3.412	7.602	EPSD	ICGC	6.822	Gain
Atypical_PIKK_FRAP_MTOR_ST	O00418	EEF2K	P42345	MTOR	S627	D633Y	633	Missense	distal	6	no	10.759	9.610	EPSD	ICGC;COSMIC	6.822	Down-regulation
Atypical_PIKK_FRAP_MTOR_ST	O00418	EEF2K	P42345	MTOR	S627	D633N	633	Missense	distal	6	no	10.759	9.809	EPSD	ICGC;COSMIC	6.822	Down-regulation
Atypical_PIKK_FRAP_MTOR_ST	O00418	EEF2K	P42345	MTOR	S627	Q632H	632	Missense	distal	5	no	10.759	11.871	EPSD	ICGC;COSMIC	6.822	Up-regulation
Atypical_PIKK_FRAP_MTOR_ST	O00418	EEF2K	P42345	MTOR	S627	D629Y	629	Missense	proximal	2	no	10.759	9.165	EPSD	ICGC;COSMIC	6.822	Down-regulation
Atypical_PIKK_FRAP_MTOR_ST	Q9UQ35	SRRM2	P42345	MTOR	T9	R11W	11	Missense	proximal	2	no	6.600	7.492	EPSD	ICGC;COSMIC	6.822	Gain
Atypical_PIKK_FRAP_MTOR_ST	Q9UQ35	SRRM2	P42345	MTOR	T9	R11L	11	Missense	proximal	2	no	6.600	8.118	EPSD	ICGC;COSMIC	6.822	Gain
Atypical_PIKK_FRAP_MTOR_ST	Q9UQ35	SRRM2	P42345	MTOR	T111	V118F	118	Missense	distal	7	no	7.502	7.570	EPSD	ICGC	6.822	Up-regulation
Atypical_PIKK_FRAP_MTOR_ST	Q9UQ35	SRRM2	P42345	MTOR	T111	G107S	107	Missense	distal	-4	no	7.502	8.069	EPSD	ICGC;COSMIC	6.822	Up-regulation
Atypical_PIKK_FRAP_MTOR_ST	Q9UQ35	SRRM2	P42345	MTOR	S172	P170S	170	Missense	proximal	-2	no	8.383	8.027	EPSD	ICGC	6.822	Down-regulation
Atypical_PIKK_FRAP_MTOR_ST	Q9UQ35	SRRM2	P42345	MTOR	S172	P165S	165	Missense	distal	-7	no	8.383	8.820	EPSD	ICGC	6.822	Up-regulation
Atypical_PIKK_FRAP_MTOR_ST	Q9UQ35	SRRM2	P42345	MTOR	S172	P168L	168	Missense	distal	-4	no	8.383	8.197	EPSD	ICGC;COSMIC	6.822	Down-regulation
Atypical_PIKK_FRAP_MTOR_ST	Q9UQ35	SRRM2	P42345	MTOR	S204	E208D	208	Missense	distal	4	no	8.276	8.438	EPSD	ICGC;COSMIC	6.822	Up-regulation
Atypical_PIKK_FRAP_MTOR_ST	Q9UQ35	SRRM2	P42345	MTOR	S231	R227H	227	Missense	distal	-4	no	9.139	7.945	EPSD	ICGC;COSMIC	6.822	Down-regulation
Atypical_PIKK_FRAP_MTOR_ST	Q9UQ35	SRRM2	P42345	MTOR	S231	R230M	230	Missense	proximal	-1	no	9.139	9.197	EPSD	ICGC;GDSC	6.822	Up-regulation
Atypical_PIKK_FRAP_MTOR_ST	Q9UQ35	SRRM2	P42345	MTOR	S231	R227L	227	Missense	distal	-4	no	9.139	8.709	EPSD	ICGC;COSMIC	6.822	Down-regulation
Atypical_PIKK_FRAP_MTOR_ST	Q9UQ35	SRRM2	P42345	MTOR	T252	R247W	247	Missense	distal	-5	no	10.245	10.303	EPSD	ICGC;COSMIC	6.822	Up-regulation
Atypical_PIKK_FRAP_MTOR_ST	Q9UQ35	SRRM2	P42345	MTOR	T252	T251K	251	Missense	proximal	-1	no	10.245	10.179	EPSD	ICGC;COSMIC	6.822	Down-regulation
Atypical_PIKK_FRAP_MTOR_ST	Q9UQ35	SRRM2	P42345	MTOR	S271	R278L	278	Missense	distal	7	no	7.939	8.124	EPSD	ICGC	6.822	Up-regulation
Atypical_PIKK_FRAP_MTOR_ST	Q9UQ35	SRRM2	P42345	MTOR	S295	P298T	298	Missense	distal	3	no	11.978	11.585	EPSD	ICGC;COSMIC	6.822	Down-regulation
Atypical_PIKK_FRAP_MTOR_ST	Q9UQ35	SRRM2	P42345	MTOR	S297	P298T	298	Missense	proximal	1	no	9.264	2.993	EPSD	ICGC;COSMIC	6.822	Loss
Atypical_PIKK_FRAP_MTOR_ST	Q9UQ35	SRRM2	P42345	MTOR	S297	R303L	303	Missense	distal	6	no	9.264	9.897	EPSD	ICGC	6.822	Up-regulation
Atypical_PIKK_FRAP_MTOR_ST	Q9UQ35	SRRM2	P42345	MTOR	S323	P324Q	324	Missense	proximal	1	no	15.265	6.651	EPSD	ICGC;COSMIC	6.822	Loss
Atypical_PIKK_FRAP_MTOR_ST	Q9UQ35	SRRM2	P42345	MTOR	S351	P354L	354	Missense	distal	3	no	12.023	9.769	EPSD	ICGC;COSMIC	6.822	Down-regulation
Atypical_PIKK_FRAP_MTOR_ST	Q9UQ35	SRRM2	P42345	MTOR	S353	P354L	354	Missense	proximal	1	no	10.140	4.170	EPSD	ICGC;COSMIC	6.822	Loss
Atypical_PIKK_FRAP_MTOR_ST	Q9UQ35	SRRM2	P42345	MTOR	T367	A365S	365	Missense	proximal	-2	no	9.152	8.591	EPSD	ICGC	6.822	Down-regulation
Atypical_PIKK_FRAP_MTOR_ST	Q9UQ35	SRRM2	P42345	MTOR	T367	A371S	371	Missense	distal	4	no	9.152	9.626	EPSD	ICGC	6.822	Up-regulation
Atypical_PIKK_FRAP_MTOR_ST	Q9UQ35	SRRM2	P42345	MTOR	T367	P366L	366	Missense	proximal	-1	no	9.152	9.018	EPSD	ICGC	6.822	Down-regulation
Atypical_PIKK_FRAP_MTOR_ST	Q9UQ35	SRRM2	P42345	MTOR	T367	P366T	366	Missense	proximal	-1	no	9.152	9.166	EPSD	ICGC	6.822	Up-regulation
Atypical_PIKK_FRAP_MTOR_ST	Q9UQ35	SRRM2	P42345	MTOR	S398	R401Q	401	Missense	distal	3	no	8.860	7.594	EPSD	ICGC;COSMIC	6.822	Down-regulation
Atypical_PIKK_FRAP_MTOR_ST	Q9UQ35	SRRM2	P42345	MTOR	S398	P394Q	394	Missense	distal	-4	no	8.860	8.606	EPSD	ICGC;COSMIC	6.822	Down-regulation
Atypical_PIKK_FRAP_MTOR_ST	Q9UQ35	SRRM2	P42345	MTOR	S398	P399S	399	Missense	proximal	1	no	8.860	0.336	EPSD	ICGC	6.822	Loss
Atypical_PIKK_FRAP_MTOR_ST	Q9UQ35	SRRM2	P42345	MTOR	S437	P438S	438	Missense	proximal	1	no	9.383	0.860	EPSD	ICGC	6.822	Loss
Atypical_PIKK_FRAP_MTOR_ST	Q9UQ35	SRRM2	P42345	MTOR	S437	R432Q	432	Missense	distal	-5	no	9.383	9.298	EPSD	ICGC;COSMIC	6.822	Down-regulation
Atypical_PIKK_FRAP_MTOR_ST	Q9UQ35	SRRM2	P42345	MTOR	T476	S478F	478	Missense	proximal	2	no	8.522	6.787	EPSD	ICGC	6.822	Loss
Atypical_PIKK_FRAP_MTOR_ST	Q9UQ35	SRRM2	P42345	MTOR	T476	T476P	476	Missense	central	0	yes	8.522	0.000	EPSD	ICGC;COSMIC	6.822	Loss
Atypical_PIKK_FRAP_MTOR_ST	Q9UQ35	SRRM2	P42345	MTOR	S486	A488S	488	Missense	proximal	2	no	9.657	10.421	EPSD	ICGC;COSMIC	6.822	Up-regulation
Atypical_PIKK_FRAP_MTOR_ST	Q9UQ35	SRRM2	P42345	MTOR	S486	G493W	493	Missense	distal	7	no	9.657	9.679	EPSD	ICGC;COSMIC	6.822	Up-regulation
Atypical_PIKK_FRAP_MTOR_ST	Q9UQ35	SRRM2	P42345	MTOR	T499	G493W	493	Missense	distal	-6	no	6.550	6.908	EPSD	ICGC;COSMIC	6.822	Gain
Atypical_PIKK_FRAP_MTOR_ST	Q9UQ35	SRRM2	P42345	MTOR	S534	R533C	533	Missense	proximal	-1	no	7.694	7.867	EPSD	ICGC;COSMIC	6.822	Up-regulation
Atypical_PIKK_FRAP_MTOR_ST	Q9UQ35	SRRM2	P42345	MTOR	S534	P537F	537	Missense	distal	3	no	7.694	8.113	EPSD	ICGC	6.822	Up-regulation
Atypical_PIKK_FRAP_MTOR_ST	Q9UQ35	SRRM2	P42345	MTOR	S534	R535S	535	Missense	proximal	1	no	7.694	9.004	EPSD	ICGC;COSMIC	6.822	Up-regulation
Atypical_PIKK_FRAP_MTOR_ST	Q9UQ35	SRRM2	P42345	MTOR	S536	S543C	543	Missense	distal	7	no	6.767	7.990	EPSD	ICGC;COSMIC	6.822	Gain
Atypical_PIKK_FRAP_MTOR_ST	Q9UQ35	SRRM2	P42345	MTOR	S536	W542L	542	Missense	distal	6	no	6.767	6.869	EPSD	ICGC	6.822	Gain
Atypical_PIKK_FRAP_MTOR_ST	Q9UQ35	SRRM2	P42345	MTOR	S536	R535S	535	Missense	proximal	-1	no	6.767	6.929	EPSD	ICGC;COSMIC	6.822	Gain
Atypical_PIKK_FRAP_MTOR_ST	Q9UQ35	SRRM2	P42345	MTOR	S543	S543C	543	Missense	central	0	yes	6.935	0.000	EPSD	ICGC;COSMIC	6.822	Loss
Atypical_PIKK_FRAP_MTOR_ST	Q9UQ35	SRRM2	P42345	MTOR	S543	W542L	542	Missense	proximal	-1	no	6.935	6.822	EPSD	ICGC	6.822	Down-regulation
Atypical_PIKK_FRAP_MTOR_ST	Q9UQ35	SRRM2	P42345	MTOR	S543	P537F	537	Missense	distal	-6	no	6.935	6.439	EPSD	ICGC	6.822	Loss
Atypical_PIKK_FRAP_MTOR_ST	Q9UQ35	SRRM2	P42345	MTOR	S566	G571V	571	Missense	distal	5	no	11.868	12.328	EPSD	ICGC	6.822	Up-regulation
Atypical_PIKK_FRAP_MTOR_ST	Q9UQ35	SRRM2	P42345	MTOR	S566	S564F	564	Missense	proximal	-2	no	11.868	12.047	EPSD	ICGC	6.822	Up-regulation
Atypical_PIKK_FRAP_MTOR_ST	Q9UQ35	SRRM2	P42345	MTOR	S566	S566P	566	Missense	central	0	yes	11.868	0.000	EPSD	ICGC;COSMIC	6.822	Loss
Atypical_PIKK_FRAP_MTOR_ST	Q9UQ35	SRRM2	P42345	MTOR	T577	S584F	584	Missense	distal	7	no	7.518	8.098	EPSD	ICGC;COSMIC	6.822	Up-regulation
Atypical_PIKK_FRAP_MTOR_ST	Q9UQ35	SRRM2	P42345	MTOR	T577	G571V	571	Missense	distal	-6	no	7.518	6.774	EPSD	ICGC	6.822	Loss
Atypical_PIKK_FRAP_MTOR_ST	Q9UQ35	SRRM2	P42345	MTOR	T577	R574L	574	Missense	distal	-3	no	7.518	7.587	EPSD	ICGC	6.822	Up-regulation
Atypical_PIKK_FRAP_MTOR_ST	Q9UQ35	SRRM2	P42345	MTOR	T588	S584F	584	Missense	distal	-4	no	8.675	8.700	EPSD	ICGC;COSMIC	6.822	Up-regulation
Atypical_PIKK_FRAP_MTOR_ST	Q9UQ35	SRRM2	P42345	MTOR	T588	R585C	585	Missense	distal	-3	no	8.675	7.963	EPSD	ICGC;COSMIC	6.822	Down-regulation
Atypical_PIKK_FRAP_MTOR_ST	Q9UQ35	SRRM2	P42345	MTOR	T588	R593I	593	Missense	distal	5	no	8.675	8.186	EPSD	ICGC	6.822	Down-regulation
Atypical_PIKK_FRAP_MTOR_ST	Q9UQ35	SRRM2	P42345	MTOR	T598	R593I	593	Missense	distal	-5	no	11.114	11.038	EPSD	ICGC	6.822	Down-regulation
Atypical_PIKK_FRAP_MTOR_ST	Q9UQ35	SRRM2	P42345	MTOR	T598	R601M	601	Missense	distal	3	no	11.114	9.014	EPSD	ICGC	6.822	Down-regulation
Atypical_PIKK_FRAP_MTOR_ST	Q9UQ35	SRRM2	P42345	MTOR	T608	R601M	601	Missense	distal	-7	no	9.975	10.147	EPSD	ICGC	6.822	Up-regulation
Atypical_PIKK_FRAP_MTOR_ST	Q9UQ35	SRRM2	P42345	MTOR	T608	R614S	614	Missense	distal	6	no	9.975	11.798	EPSD	ICGC	6.822	Up-regulation
Atypical_PIKK_FRAP_MTOR_ST	Q9UQ35	SRRM2	P42345	MTOR	T619	A621P	621	Missense	proximal	2	no	8.869	10.127	EPSD	ICGC;COSMIC	6.822	Up-regulation
Atypical_PIKK_FRAP_MTOR_ST	Q9UQ35	SRRM2	P42345	MTOR	T619	R623L	623	Missense	distal	4	no	8.869	8.802	EPSD	ICGC;COSMIC	6.822	Down-regulation
Atypical_PIKK_FRAP_MTOR_ST	Q9UQ35	SRRM2	P42345	MTOR	T619	R614S	614	Missense	distal	-5	no	8.869	8.727	EPSD	ICGC	6.822	Down-regulation
Atypical_PIKK_FRAP_MTOR_ST	Q9UQ35	SRRM2	P42345	MTOR	S629	R633C	633	Missense	distal	4	no	10.965	10.752	EPSD	ICGC;COSMIC	6.822	Down-regulation
Atypical_PIKK_FRAP_MTOR_ST	Q9UQ35	SRRM2	P42345	MTOR	S629	R623L	623	Missense	distal	-6	no	10.965	10.104	EPSD	ICGC;COSMIC	6.822	Down-regulation
Atypical_PIKK_FRAP_MTOR_ST	Q9UQ35	SRRM2	P42345	MTOR	S639	R633C	633	Missense	distal	-6	no	15.180	15.307	EPSD	ICGC;COSMIC	6.822	Up-regulation
Atypical_PIKK_FRAP_MTOR_ST	Q9UQ35	SRRM2	P42345	MTOR	S639	S639L	639	Missense	central	0	yes	15.180	0.000	EPSD	ICGC;COSMIC	6.822	Loss
Atypical_PIKK_FRAP_MTOR_ST	Q9UQ35	SRRM2	P42345	MTOR	T662	G667C	667	Missense	distal	5	no	7.283	7.397	EPSD	ICGC;COSMIC	6.822	Up-regulation
Atypical_PIKK_FRAP_MTOR_ST	Q9UQ35	SRRM2	P42345	MTOR	T662	S669A	669	Missense	distal	7	no	7.283	6.858	EPSD	ICGC;COSMIC	6.822	Down-regulation
Atypical_PIKK_FRAP_MTOR_ST	Q9UQ35	SRRM2	P42345	MTOR	T673	A675G	675	Missense	proximal	2	no	6.771	7.356	EPSD	ICGC;COSMIC	6.822	Gain
Atypical_PIKK_FRAP_MTOR_ST	Q9UQ35	SRRM2	P42345	MTOR	T673	G667C	667	Missense	distal	-6	no	6.771	6.884	EPSD	ICGC;COSMIC	6.822	Gain
Atypical_PIKK_FRAP_MTOR_ST	Q9UQ35	SRRM2	P42345	MTOR	S727	S728L	728	Missense	proximal	1	no	10.594	13.148	EPSD	ICGC	6.822	Up-regulation
Atypical_PIKK_FRAP_MTOR_ST	Q9UQ35	SRRM2	P42345	MTOR	S727	S734F	734	Missense	distal	7	no	10.594	11.174	EPSD	ICGC	6.822	Up-regulation
Atypical_PIKK_FRAP_MTOR_ST	Q9UQ35	SRRM2	P42345	MTOR	S761	R766L	766	Missense	distal	5	no	9.676	10.171	EPSD	ICGC;COSMIC	6.822	Up-regulation
Atypical_PIKK_FRAP_MTOR_ST	Q9UQ35	SRRM2	P42345	MTOR	S764	R766L	766	Missense	proximal	2	no	10.278	11.795	EPSD	ICGC;COSMIC	6.822	Up-regulation
Atypical_PIKK_FRAP_MTOR_ST	Q9UQ35	SRRM2	P42345	MTOR	S778	C785F	785	Missense	distal	7	no	7.398	6.755	EPSD	ICGC;GDSC;CCLE	6.822	Loss
Atypical_PIKK_FRAP_MTOR_ST	Q9UQ35	SRRM2	P42345	MTOR	S778	R772C	772	Missense	distal	-6	no	7.398	7.525	EPSD	ICGC;COSMIC	6.822	Up-regulation
Atypical_PIKK_FRAP_MTOR_ST	Q9UQ35	SRRM2	P42345	MTOR	S783	C785F	785	Missense	proximal	2	no	10.880	10.692	EPSD	ICGC;GDSC;CCLE	6.822	Down-regulation
Atypical_PIKK_FRAP_MTOR_ST	Q9UQ35	SRRM2	P42345	MTOR	T792	S797G	797	Missense	distal	5	no	8.079	8.741	EPSD	ICGC;COSMIC	6.822	Up-regulation
Atypical_PIKK_FRAP_MTOR_ST	Q9UQ35	SRRM2	P42345	MTOR	T792	C785F	785	Missense	distal	-7	no	8.079	9.707	EPSD	ICGC;GDSC;CCLE	6.822	Up-regulation
Atypical_PIKK_FRAP_MTOR_ST	Q9UQ35	SRRM2	P42345	MTOR	T792	R798C	798	Missense	distal	6	no	8.079	8.206	EPSD	ICGC	6.822	Up-regulation
Atypical_PIKK_FRAP_MTOR_ST	Q9UQ35	SRRM2	P42345	MTOR	T810	S817C	817	Missense	distal	7	no	6.549	7.772	EPSD	ICGC;COSMIC;GDSC;CCLE	6.822	Gain
Atypical_PIKK_FRAP_MTOR_ST	Q9UQ35	SRRM2	P42345	MTOR	S820	S827Y	827	Missense	distal	7	no	11.057	10.658	EPSD	ICGC;COSMIC	6.822	Down-regulation
Atypical_PIKK_FRAP_MTOR_ST	Q9UQ35	SRRM2	P42345	MTOR	S820	S817C	817	Missense	distal	-3	no	11.057	10.691	EPSD	ICGC;COSMIC;GDSC;CCLE	6.822	Down-regulation
Atypical_PIKK_FRAP_MTOR_ST	Q9UQ35	SRRM2	P42345	MTOR	T866	S864C	864	Missense	proximal	-2	no	7.535	7.685	EPSD	ICGC;COSMIC	6.822	Up-regulation
Atypical_PIKK_FRAP_MTOR_ST	Q9UQ35	SRRM2	P42345	MTOR	T885	R884M	884	Missense	proximal	-1	no	11.329	11.388	EPSD	ICGC;COSMIC	6.822	Up-regulation
Atypical_PIKK_FRAP_MTOR_ST	Q9UQ35	SRRM2	P42345	MTOR	S895	P897L	897	Missense	proximal	2	no	7.644	6.955	EPSD	ICGC;COSMIC	6.822	Down-regulation
Atypical_PIKK_FRAP_MTOR_ST	Q9UQ35	SRRM2	P42345	MTOR	T903	P897L	897	Missense	distal	-6	no	9.614	8.839	EPSD	ICGC;COSMIC	6.822	Down-regulation
Atypical_PIKK_FRAP_MTOR_ST	Q9UQ35	SRRM2	P42345	MTOR	T903	S908N	908	Missense	distal	5	no	9.614	11.095	EPSD	ICGC;COSMIC	6.822	Up-regulation
Atypical_PIKK_FRAP_MTOR_ST	Q9UQ35	SRRM2	P42345	MTOR	S908	S908N	908	Missense	central	0	yes	8.321	0.000	EPSD	ICGC;COSMIC	6.822	Loss
Atypical_PIKK_FRAP_MTOR_ST	Q9UQ35	SRRM2	P42345	MTOR	S935	V941L	941	Missense	distal	6	no	11.289	10.058	EPSD	ICGC	6.822	Down-regulation
Atypical_PIKK_FRAP_MTOR_ST	Q9UQ35	SRRM2	P42345	MTOR	S935	R940G	940	Missense	distal	5	no	11.289	10.959	EPSD	ICGC;COSMIC	6.822	Down-regulation
Atypical_PIKK_FRAP_MTOR_ST	Q9UQ35	SRRM2	P42345	MTOR	S937	V941L	941	Missense	distal	4	no	9.099	8.771	EPSD	ICGC	6.822	Down-regulation
Atypical_PIKK_FRAP_MTOR_ST	Q9UQ35	SRRM2	P42345	MTOR	S937	R940G	940	Missense	distal	3	no	9.099	10.446	EPSD	ICGC;COSMIC	6.822	Up-regulation
Atypical_PIKK_FRAP_MTOR_ST	Q9UQ35	SRRM2	P42345	MTOR	S954	R949Q	949	Missense	distal	-5	no	10.223	10.138	EPSD	ICGC	6.822	Down-regulation
Atypical_PIKK_FRAP_MTOR_ST	Q9UQ35	SRRM2	P42345	MTOR	S954	S950I	950	Missense	distal	-4	no	10.223	9.297	EPSD	ICGC	6.822	Down-regulation
Atypical_PIKK_FRAP_MTOR_ST	Q9UQ35	SRRM2	P42345	MTOR	S954	R951I	951	Missense	distal	-3	no	10.223	10.312	EPSD	ICGC	6.822	Up-regulation
Atypical_PIKK_FRAP_MTOR_ST	Q9UQ35	SRRM2	P42345	MTOR	S974	G971V	971	Missense	distal	-3	no	14.879	14.643	EPSD	ICGC	6.822	Down-regulation
Atypical_PIKK_FRAP_MTOR_ST	Q9UQ35	SRRM2	P42345	MTOR	T1003	P1005L	1005	Missense	proximal	2	no	7.281	6.591	EPSD	ICGC;COSMIC	6.822	Loss
Atypical_PIKK_FRAP_MTOR_ST	Q9UQ35	SRRM2	P42345	MTOR	S1073	D1066V	1066	Missense	distal	-7	no	9.445	8.472	EPSD	ICGC;COSMIC	6.822	Down-regulation
Atypical_PIKK_FRAP_MTOR_ST	Q9UQ35	SRRM2	P42345	MTOR	S1093	K1095M	1095	Missense	proximal	2	no	10.087	8.719	EPSD	ICGC;COSMIC	6.822	Down-regulation
Atypical_PIKK_FRAP_MTOR_ST	Q9UQ35	SRRM2	P42345	MTOR	S1093	R1098W	1098	Missense	distal	5	no	10.087	9.104	EPSD	ICGC;COSMIC;GDSC;CCLE	6.822	Down-regulation
Atypical_PIKK_FRAP_MTOR_ST	Q9UQ35	SRRM2	P42345	MTOR	S1093	Q1087H	1087	Missense	distal	-6	no	10.087	9.544	EPSD	ICGC;COSMIC	6.822	Down-regulation
Atypical_PIKK_FRAP_MTOR_ST	Q9UQ35	SRRM2	P42345	MTOR	S1103	R1098W	1098	Missense	distal	-5	no	8.453	8.510	EPSD	ICGC;COSMIC;GDSC;CCLE	6.822	Up-regulation
Atypical_PIKK_FRAP_MTOR_ST	Q9UQ35	SRRM2	P42345	MTOR	S1103	V1105F	1105	Missense	proximal	2	no	8.453	6.734	EPSD	ICGC;COSMIC	6.822	Loss
Atypical_PIKK_FRAP_MTOR_ST	Q9UQ35	SRRM2	P42345	MTOR	S1144	P1146S	1146	Missense	proximal	2	no	9.835	9.341	EPSD	ICGC;COSMIC	6.822	Down-regulation
Atypical_PIKK_FRAP_MTOR_ST	Q9UQ35	SRRM2	P42345	MTOR	S1144	V1148M	1148	Missense	distal	4	no	9.835	10.001	EPSD	ICGC;COSMIC	6.822	Up-regulation
Atypical_PIKK_FRAP_MTOR_ST	Q9UQ35	SRRM2	P42345	MTOR	S1179	D1175E	1175	Missense	distal	-4	no	7.467	6.317	EPSD	ICGC	6.822	Loss
Atypical_PIKK_FRAP_MTOR_ST	Q9UQ35	SRRM2	P42345	MTOR	S1311	S1318F	1318	Missense	distal	7	no	8.166	8.746	EPSD	ICGC;COSMIC	6.822	Up-regulation
Atypical_PIKK_FRAP_MTOR_ST	Q9UQ35	SRRM2	P42345	MTOR	S1311	S1304F	1304	Missense	distal	-7	no	8.166	7.941	EPSD	ICGC	6.822	Down-regulation
Atypical_PIKK_FRAP_MTOR_ST	Q9UQ35	SRRM2	P42345	MTOR	S1311	L1317M	1317	Missense	distal	6	no	8.166	7.971	EPSD	ICGC	6.822	Down-regulation
Atypical_PIKK_FRAP_MTOR_ST	Q9UQ35	SRRM2	P42345	MTOR	S1311	G1306S	1306	Missense	distal	-5	no	8.166	8.098	EPSD	ICGC	6.822	Down-regulation
Atypical_PIKK_FRAP_MTOR_ST	Q9UQ35	SRRM2	P42345	MTOR	S1318	S1318F	1318	Missense	central	0	yes	7.678	0.000	EPSD;PhosphoSitePlus	ICGC;COSMIC	6.822	Loss
Atypical_PIKK_FRAP_MTOR_ST	Q9UQ35	SRRM2	P42345	MTOR	S1318	L1317M	1317	Missense	proximal	-1	no	7.678	7.777	EPSD;PhosphoSitePlus	ICGC	6.822	Up-regulation
Atypical_PIKK_FRAP_MTOR_ST	Q9UQ35	SRRM2	P42345	MTOR	S1320	S1318F	1318	Missense	proximal	-2	no	13.108	13.286	EPSD	ICGC;COSMIC	6.822	Up-regulation
Atypical_PIKK_FRAP_MTOR_ST	Q9UQ35	SRRM2	P42345	MTOR	S1320	L1317M	1317	Missense	distal	-3	no	13.108	11.840	EPSD	ICGC	6.822	Down-regulation
Atypical_PIKK_FRAP_MTOR_ST	Q9UQ35	SRRM2	P42345	MTOR	S1387	S1382I	1382	Missense	distal	-5	no	9.596	9.661	EPSD	ICGC	6.822	Up-regulation
Atypical_PIKK_FRAP_MTOR_ST	Q9UQ35	SRRM2	P42345	MTOR	S1444	S1443C	1443	Missense	proximal	-1	no	12.094	12.105	EPSD	ICGC;COSMIC	6.822	Up-regulation
Atypical_PIKK_FRAP_MTOR_ST	Q9UQ35	SRRM2	P42345	MTOR	S1444	G1450V	1450	Missense	distal	6	no	12.094	12.205	EPSD	ICGC	6.822	Up-regulation
Atypical_PIKK_FRAP_MTOR_ST	Q9UQ35	SRRM2	P42345	MTOR	T1453	S1455L	1455	Missense	proximal	2	no	11.406	11.211	EPSD	ICGC;COSMIC	6.822	Down-regulation
Atypical_PIKK_FRAP_MTOR_ST	Q9UQ35	SRRM2	P42345	MTOR	T1453	G1450V	1450	Missense	distal	-3	no	11.406	11.170	EPSD	ICGC	6.822	Down-regulation
Atypical_PIKK_FRAP_MTOR_ST	Q9UQ35	SRRM2	P42345	MTOR	T1453	S1460A	1460	Missense	distal	7	no	11.406	10.981	EPSD	ICGC	6.822	Down-regulation
Atypical_PIKK_FRAP_MTOR_ST	Q9UQ35	SRRM2	P42345	MTOR	S1463	P1470H	1470	Missense	distal	7	no	7.571	8.185	EPSD	ICGC;COSMIC	6.822	Up-regulation
Atypical_PIKK_FRAP_MTOR_ST	Q9UQ35	SRRM2	P42345	MTOR	S1463	G1461V	1461	Missense	proximal	-2	no	7.571	6.923	EPSD	ICGC;COSMIC	6.822	Down-regulation
Atypical_PIKK_FRAP_MTOR_ST	Q9UQ35	SRRM2	P42345	MTOR	S1463	S1460A	1460	Missense	distal	-3	no	7.571	7.077	EPSD	ICGC	6.822	Down-regulation
Atypical_PIKK_FRAP_MTOR_ST	Q9UQ35	SRRM2	P42345	MTOR	S1463	D1468A	1468	Missense	distal	5	no	7.571	7.964	EPSD	ICGC;COSMIC	6.822	Up-regulation
Atypical_PIKK_FRAP_MTOR_ST	Q9UQ35	SRRM2	P42345	MTOR	T1472	S1474A	1474	Missense	proximal	2	no	11.668	10.905	EPSD	ICGC;COSMIC	6.822	Down-regulation
Atypical_PIKK_FRAP_MTOR_ST	Q9UQ35	SRRM2	P42345	MTOR	T1472	E1479K	1479	Missense	distal	7	no	11.668	11.765	EPSD	ICGC	6.822	Up-regulation
Atypical_PIKK_FRAP_MTOR_ST	Q9UQ35	SRRM2	P42345	MTOR	T1472	P1470H	1470	Missense	proximal	-2	no	11.668	10.954	EPSD	ICGC;COSMIC	6.822	Down-regulation
Atypical_PIKK_FRAP_MTOR_ST	Q9UQ35	SRRM2	P42345	MTOR	T1472	D1468A	1468	Missense	distal	-4	no	11.668	9.676	EPSD	ICGC;COSMIC	6.822	Down-regulation
Atypical_PIKK_FRAP_MTOR_ST	Q9UQ35	SRRM2	P42345	MTOR	S1483	E1479K	1479	Missense	distal	-4	no	7.968	7.670	EPSD	ICGC	6.822	Down-regulation
Atypical_PIKK_FRAP_MTOR_ST	Q9UQ35	SRRM2	P42345	MTOR	S1483	A1488S	1488	Missense	distal	5	no	7.968	7.540	EPSD	ICGC	6.822	Down-regulation
Atypical_PIKK_FRAP_MTOR_ST	Q9UQ35	SRRM2	P42345	MTOR	T1492	A1488S	1488	Missense	distal	-4	no	7.770	8.733	EPSD	ICGC	6.822	Up-regulation
Atypical_PIKK_FRAP_MTOR_ST	Q9UQ35	SRRM2	P42345	MTOR	T1511	G1518R	1518	Missense	distal	7	no	8.008	8.416	EPSD	ICGC;COSMIC	6.822	Up-regulation
Atypical_PIKK_FRAP_MTOR_ST	Q9UQ35	SRRM2	P42345	MTOR	T1511	S1517I	1517	Missense	distal	6	no	8.008	7.144	EPSD	ICGC;COSMIC	6.822	Down-regulation
Atypical_PIKK_FRAP_MTOR_ST	Q9UQ35	SRRM2	P42345	MTOR	T1531	R1538L	1538	Missense	distal	7	no	13.389	13.573	EPSD	ICGC	6.822	Up-regulation
Atypical_PIKK_FRAP_MTOR_ST	Q9UQ35	SRRM2	P42345	MTOR	T1531	R1530Q	1530	Missense	proximal	-1	no	13.389	13.408	EPSD	ICGC;COSMIC	6.822	Up-regulation
Atypical_PIKK_FRAP_MTOR_ST	Q9UQ35	SRRM2	P42345	MTOR	S1552	A1551S	1551	Missense	proximal	-1	no	8.000	8.006	EPSD	ICGC	6.822	Up-regulation
Atypical_PIKK_FRAP_MTOR_ST	Q9UQ35	SRRM2	P42345	MTOR	T1571	R1570I	1570	Missense	proximal	-1	no	9.712	9.638	EPSD	ICGC	6.822	Down-regulation
Atypical_PIKK_FRAP_MTOR_ST	Q9UQ35	SRRM2	P42345	MTOR	S1592	R1594L	1594	Missense	proximal	2	no	8.450	9.968	EPSD	ICGC;COSMIC	6.822	Up-regulation
Atypical_PIKK_FRAP_MTOR_ST	Q9UQ35	SRRM2	P42345	MTOR	S1621	P1624H	1624	Missense	distal	3	no	8.173	8.077	EPSD	ICGC;COSMIC	6.822	Down-regulation
Atypical_PIKK_FRAP_MTOR_ST	Q9UQ35	SRRM2	P42345	MTOR	S1621	A1626S	1626	Missense	distal	5	no	8.173	7.745	EPSD	ICGC;COSMIC	6.822	Down-regulation
Atypical_PIKK_FRAP_MTOR_ST	Q9UQ35	SRRM2	P42345	MTOR	S1648	S1653I	1653	Missense	distal	5	no	14.914	15.417	EPSD	ICGC	6.822	Up-regulation
Atypical_PIKK_FRAP_MTOR_ST	Q9UQ35	SRRM2	P42345	MTOR	S1648	E1650K	1650	Missense	proximal	2	no	14.914	14.009	EPSD	ICGC;COSMIC	6.822	Down-regulation
Atypical_PIKK_FRAP_MTOR_ST	Q9UQ35	SRRM2	P42345	MTOR	S1652	S1653I	1653	Missense	proximal	1	no	3.909	7.375	EPSD	ICGC	6.822	Gain
Atypical_PIKK_FRAP_MTOR_ST	Q9UQ35	SRRM2	P42345	MTOR	S1654	E1656K	1656	Missense	proximal	2	no	9.153	8.248	EPSD	ICGC;COSMIC	6.822	Down-regulation
Atypical_PIKK_FRAP_MTOR_ST	Q9UQ35	SRRM2	P42345	MTOR	S1654	S1653I	1653	Missense	proximal	-1	no	9.153	8.917	EPSD	ICGC	6.822	Down-regulation
Atypical_PIKK_FRAP_MTOR_ST	Q9UQ35	SRRM2	P42345	MTOR	S1654	E1650K	1650	Missense	distal	-4	no	9.153	8.855	EPSD	ICGC;COSMIC	6.822	Down-regulation
Atypical_PIKK_FRAP_MTOR_ST	Q9UQ35	SRRM2	P42345	MTOR	S1658	E1656K	1656	Missense	proximal	-2	no	11.333	11.372	EPSD	ICGC;COSMIC	6.822	Up-regulation
Atypical_PIKK_FRAP_MTOR_ST	Q9UQ35	SRRM2	P42345	MTOR	S1658	S1653I	1653	Missense	distal	-5	no	11.333	11.398	EPSD	ICGC	6.822	Up-regulation
Atypical_PIKK_FRAP_MTOR_ST	Q9UQ35	SRRM2	P42345	MTOR	S1675	G1671V	1671	Missense	distal	-4	no	7.276	7.160	EPSD	ICGC;COSMIC	6.822	Down-regulation
Atypical_PIKK_FRAP_MTOR_ST	Q9UQ35	SRRM2	P42345	MTOR	S1675	R1669S	1669	Missense	distal	-6	no	7.276	7.169	EPSD	ICGC;COSMIC	6.822	Down-regulation
Atypical_PIKK_FRAP_MTOR_ST	Q9UQ35	SRRM2	P42345	MTOR	T1684	R1689C	1689	Missense	distal	5	no	8.317	8.102	EPSD	ICGC;COSMIC	6.822	Down-regulation
Atypical_PIKK_FRAP_MTOR_ST	Q9UQ35	SRRM2	P42345	MTOR	S1694	P1695Q	1695	Missense	proximal	1	no	11.187	2.573	EPSD	ICGC;COSMIC	6.822	Loss
Atypical_PIKK_FRAP_MTOR_ST	Q9UQ35	SRRM2	P42345	MTOR	S1694	R1689C	1689	Missense	distal	-5	no	11.187	11.311	EPSD	ICGC;COSMIC	6.822	Up-regulation
Atypical_PIKK_FRAP_MTOR_ST	Q9UQ35	SRRM2	P42345	MTOR	S1713	R1717C	1717	Missense	distal	4	no	8.910	8.697	EPSD	ICGC;COSMIC	6.822	Down-regulation
Atypical_PIKK_FRAP_MTOR_ST	Q9UQ35	SRRM2	P42345	MTOR	S1713	S1707R	1707	Missense	distal	-6	no	8.910	9.018	EPSD	ICGC;COSMIC	6.822	Up-regulation
Atypical_PIKK_FRAP_MTOR_ST	Q9UQ35	SRRM2	P42345	MTOR	S1713	R1708H	1708	Missense	distal	-5	no	8.910	8.915	EPSD	ICGC;COSMIC	6.822	Up-regulation
Atypical_PIKK_FRAP_MTOR_ST	Q9UQ35	SRRM2	P42345	MTOR	T1720	R1717C	1717	Missense	distal	-3	no	7.016	6.304	EPSD	ICGC;COSMIC	6.822	Loss
Atypical_PIKK_FRAP_MTOR_ST	Q9UQ35	SRRM2	P42345	MTOR	S1727	P1733L	1733	Missense	distal	6	no	10.374	9.214	EPSD	ICGC;COSMIC	6.822	Down-regulation
Atypical_PIKK_FRAP_MTOR_ST	Q9UQ35	SRRM2	P42345	MTOR	S1732	P1733L	1733	Missense	proximal	1	no	10.028	4.059	EPSD	ICGC;COSMIC	6.822	Loss
Atypical_PIKK_FRAP_MTOR_ST	Q9UQ35	SRRM2	P42345	MTOR	S1762	R1768C	1768	Missense	distal	6	no	10.436	10.563	EPSD	ICGC;COSMIC	6.822	Up-regulation
Atypical_PIKK_FRAP_MTOR_ST	Q9UQ35	SRRM2	P42345	MTOR	S1762	R1768H	1768	Missense	distal	6	no	10.436	10.752	EPSD	ICGC	6.822	Up-regulation
Atypical_PIKK_FRAP_MTOR_ST	Q9UQ35	SRRM2	P42345	MTOR	S1762	P1765S	1765	Missense	distal	3	no	10.436	10.450	EPSD	ICGC;COSMIC	6.822	Up-regulation
Atypical_PIKK_FRAP_MTOR_ST	Q9UQ35	SRRM2	P42345	MTOR	S1764	R1768C	1768	Missense	distal	4	no	10.855	10.642	EPSD	ICGC;COSMIC	6.822	Down-regulation
Atypical_PIKK_FRAP_MTOR_ST	Q9UQ35	SRRM2	P42345	MTOR	S1764	R1768H	1768	Missense	distal	4	no	10.855	10.596	EPSD	ICGC	6.822	Down-regulation
Atypical_PIKK_FRAP_MTOR_ST	Q9UQ35	SRRM2	P42345	MTOR	S1764	P1765S	1765	Missense	proximal	1	no	10.855	2.331	EPSD	ICGC;COSMIC	6.822	Loss
Atypical_PIKK_FRAP_MTOR_ST	Q9UQ35	SRRM2	P42345	MTOR	S1824	A1826V	1826	Missense	proximal	2	no	8.458	9.206	EPSD	ICGC	6.822	Up-regulation
Atypical_PIKK_FRAP_MTOR_ST	Q9UQ35	SRRM2	P42345	MTOR	S1824	R1823S	1823	Missense	proximal	-1	no	8.458	8.620	EPSD	ICGC	6.822	Up-regulation
Atypical_PIKK_FRAP_MTOR_ST	Q9UQ35	SRRM2	P42345	MTOR	S1824	S1831F	1831	Missense	distal	7	no	8.458	9.039	EPSD	ICGC	6.822	Up-regulation
Atypical_PIKK_FRAP_MTOR_ST	Q9UQ35	SRRM2	P42345	MTOR	S1824	G1819V	1819	Missense	distal	-5	no	8.458	8.329	EPSD	ICGC;COSMIC	6.822	Down-regulation
Atypical_PIKK_FRAP_MTOR_ST	Q9UQ35	SRRM2	P42345	MTOR	T1844	R1837H	1837	Missense	distal	-7	no	10.177	9.828	EPSD	ICGC;COSMIC	6.822	Down-regulation
Atypical_PIKK_FRAP_MTOR_ST	Q9UQ35	SRRM2	P42345	MTOR	T1844	R1851H	1851	Missense	distal	7	no	10.177	10.020	EPSD	ICGC;COSMIC	6.822	Down-regulation
Atypical_PIKK_FRAP_MTOR_ST	Q9UQ35	SRRM2	P42345	MTOR	T1844	R1843W	1843	Missense	proximal	-1	no	10.177	10.250	EPSD	ICGC	6.822	Up-regulation
Atypical_PIKK_FRAP_MTOR_ST	Q9UQ35	SRRM2	P42345	MTOR	S1857	T1856I	1856	Missense	proximal	-1	no	8.858	8.675	EPSD	ICGC;COSMIC	6.822	Down-regulation
Atypical_PIKK_FRAP_MTOR_ST	Q9UQ35	SRRM2	P42345	MTOR	S1857	R1851H	1851	Missense	distal	-6	no	8.858	8.051	EPSD	ICGC;COSMIC	6.822	Down-regulation
Atypical_PIKK_FRAP_MTOR_ST	Q9UQ35	SRRM2	P42345	MTOR	S1857	R1863L	1863	Missense	distal	6	no	8.858	9.490	EPSD	ICGC	6.822	Up-regulation
Atypical_PIKK_FRAP_MTOR_ST	Q9UQ35	SRRM2	P42345	MTOR	S1864	R1865I	1865	Missense	proximal	1	no	4.133	8.908	EPSD	ICGC	6.822	Gain
Atypical_PIKK_FRAP_MTOR_ST	Q9UQ35	SRRM2	P42345	MTOR	S1869	R1875Q	1875	Missense	distal	6	no	6.552	6.936	EPSD	ICGC;COSMIC	6.822	Gain
Atypical_PIKK_FRAP_MTOR_ST	Q9UQ35	SRRM2	P42345	MTOR	S1893	R1899Q	1899	Missense	distal	6	no	11.074	11.458	EPSD	ICGC;GDSC;CCLE	6.822	Up-regulation
Atypical_PIKK_FRAP_MTOR_ST	Q9UQ35	SRRM2	P42345	MTOR	S1916	R1910T	1910	Missense	distal	-6	no	9.550	9.384	EPSD	ICGC;COSMIC	6.822	Down-regulation
Atypical_PIKK_FRAP_MTOR_ST	Q9UQ35	SRRM2	P42345	MTOR	S1916	S1916P	1916	Missense	central	0	yes	9.550	0.000	EPSD	ICGC;COSMIC	6.822	Loss
Atypical_PIKK_FRAP_MTOR_ST	Q9UQ35	SRRM2	P42345	MTOR	S1916	S1916Y	1916	Missense	central	0	yes	9.550	0.000	EPSD	ICGC;COSMIC	6.822	Loss
Atypical_PIKK_FRAP_MTOR_ST	Q9UQ35	SRRM2	P42345	MTOR	S1916	S1913A	1913	Missense	distal	-3	no	9.550	9.056	EPSD	ICGC	6.822	Down-regulation
Atypical_PIKK_FRAP_MTOR_ST	Q9UQ35	SRRM2	P42345	MTOR	T1927	R1932H	1932	Missense	distal	5	no	9.658	9.963	EPSD	ICGC;COSMIC;GDSC;CCLE	6.822	Up-regulation
Atypical_PIKK_FRAP_MTOR_ST	Q9UQ35	SRRM2	P42345	MTOR	T1927	R1932S	1932	Missense	distal	5	no	9.658	8.665	EPSD	ICGC;COSMIC	6.822	Down-regulation
Atypical_PIKK_FRAP_MTOR_ST	Q9UQ35	SRRM2	P42345	MTOR	T1939	T1939M	1939	Missense	central	0	yes	10.018	0.000	EPSD	ICGC;COSMIC	6.822	Loss
Atypical_PIKK_FRAP_MTOR_ST	Q9UQ35	SRRM2	P42345	MTOR	T1939	R1932H	1932	Missense	distal	-7	no	10.018	9.669	EPSD	ICGC;COSMIC;GDSC;CCLE	6.822	Down-regulation
Atypical_PIKK_FRAP_MTOR_ST	Q9UQ35	SRRM2	P42345	MTOR	T1939	R1932S	1932	Missense	distal	-7	no	10.018	10.777	EPSD	ICGC;COSMIC	6.822	Up-regulation
Atypical_PIKK_FRAP_MTOR_ST	Q9UQ35	SRRM2	P42345	MTOR	T1950	T1950P	1950	Missense	central	0	yes	11.438	0.000	EPSD	ICGC;COSMIC	6.822	Loss
Atypical_PIKK_FRAP_MTOR_ST	Q9UQ35	SRRM2	P42345	MTOR	T1950	R1947C	1947	Missense	distal	-3	no	11.438	10.726	EPSD	ICGC;COSMIC	6.822	Down-regulation
Atypical_PIKK_FRAP_MTOR_ST	Q9UQ35	SRRM2	P42345	MTOR	T1950	P1951L	1951	Missense	proximal	1	no	11.438	5.469	EPSD	ICGC	6.822	Loss
Atypical_PIKK_FRAP_MTOR_ST	Q9UQ35	SRRM2	P42345	MTOR	S1975	R1979C	1979	Missense	distal	4	no	9.092	8.879	EPSD	ICGC;COSMIC	6.822	Down-regulation
Atypical_PIKK_FRAP_MTOR_ST	Q9UQ35	SRRM2	P42345	MTOR	S1999	R1997C	1997	Missense	proximal	-2	no	9.503	9.781	EPSD	ICGC;COSMIC	6.822	Up-regulation
Atypical_PIKK_FRAP_MTOR_ST	Q9UQ35	SRRM2	P42345	MTOR	S1999	S1996P	1996	Missense	distal	-3	no	9.503	9.071	EPSD	ICGC;COSMIC	6.822	Down-regulation
Atypical_PIKK_FRAP_MTOR_ST	Q9UQ35	SRRM2	P42345	MTOR	S1999	S2006Y	2006	Missense	distal	7	no	9.503	9.105	EPSD	ICGC;COSMIC	6.822	Down-regulation
Atypical_PIKK_FRAP_MTOR_ST	Q9UQ35	SRRM2	P42345	MTOR	S2011	S2006Y	2006	Missense	distal	-5	no	9.536	10.029	EPSD	ICGC;COSMIC	6.822	Up-regulation
Atypical_PIKK_FRAP_MTOR_ST	Q9UQ35	SRRM2	P42345	MTOR	S2011	R2016C	2016	Missense	distal	5	no	9.536	9.320	EPSD	ICGC	6.822	Down-regulation
Atypical_PIKK_FRAP_MTOR_ST	Q9UQ35	SRRM2	P42345	MTOR	T2022	S2020F	2020	Missense	proximal	-2	no	8.270	8.448	EPSD	ICGC;COSMIC	6.822	Up-regulation
Atypical_PIKK_FRAP_MTOR_ST	Q9UQ35	SRRM2	P42345	MTOR	T2022	R2027W	2027	Missense	distal	5	no	8.270	7.287	EPSD	ICGC	6.822	Down-regulation
Atypical_PIKK_FRAP_MTOR_ST	Q9UQ35	SRRM2	P42345	MTOR	T2022	A2025S	2025	Missense	distal	3	no	8.270	7.215	EPSD	ICGC;COSMIC	6.822	Down-regulation
Atypical_PIKK_FRAP_MTOR_ST	Q9UQ35	SRRM2	P42345	MTOR	T2022	R2016C	2016	Missense	distal	-6	no	8.270	8.397	EPSD	ICGC	6.822	Up-regulation
Atypical_PIKK_FRAP_MTOR_ST	Q9UQ35	SRRM2	P42345	MTOR	T2034	R2041H	2041	Missense	distal	7	no	8.206	8.049	EPSD	ICGC;COSMIC	6.822	Down-regulation
Atypical_PIKK_FRAP_MTOR_ST	Q9UQ35	SRRM2	P42345	MTOR	T2034	R2027W	2027	Missense	distal	-7	no	8.206	8.667	EPSD	ICGC	6.822	Up-regulation
Atypical_PIKK_FRAP_MTOR_ST	Q9UQ35	SRRM2	P42345	MTOR	T2034	T2034M	2034	Missense	central	0	yes	8.206	0.000	EPSD	ICGC;COSMIC	6.822	Loss
Atypical_PIKK_FRAP_MTOR_ST	Q9UQ35	SRRM2	P42345	MTOR	T2034	S2032Y	2032	Missense	proximal	-2	no	8.206	7.664	EPSD	ICGC	6.822	Down-regulation
Atypical_PIKK_FRAP_MTOR_ST	Q9UQ35	SRRM2	P42345	MTOR	S2042	R2043L	2043	Missense	proximal	1	no	3.584	7.448	EPSD	ICGC;COSMIC	6.822	Gain
Atypical_PIKK_FRAP_MTOR_ST	Q9UQ35	SRRM2	P42345	MTOR	S2046	R2045H	2045	Missense	proximal	-1	no	10.758	10.799	EPSD	ICGC	6.822	Up-regulation
Atypical_PIKK_FRAP_MTOR_ST	Q9UQ35	SRRM2	P42345	MTOR	S2046	R2041H	2041	Missense	distal	-5	no	10.758	10.762	EPSD	ICGC;COSMIC	6.822	Up-regulation
Atypical_PIKK_FRAP_MTOR_ST	Q9UQ35	SRRM2	P42345	MTOR	S2046	R2043L	2043	Missense	distal	-3	no	10.758	10.827	EPSD	ICGC;COSMIC	6.822	Up-regulation
Atypical_PIKK_FRAP_MTOR_ST	Q9UQ35	SRRM2	P42345	MTOR	T2058	A2062T	2062	Missense	distal	4	no	11.832	12.374	EPSD	ICGC	6.822	Up-regulation
Atypical_PIKK_FRAP_MTOR_ST	Q9UQ35	SRRM2	P42345	MTOR	T2058	P2059T	2059	Missense	proximal	1	no	11.832	5.560	EPSD	ICGC;COSMIC	6.822	Loss
Atypical_PIKK_FRAP_MTOR_ST	Q9UQ35	SRRM2	P42345	MTOR	T2092	D2086V	2086	Missense	distal	-6	no	10.428	9.702	EPSD	ICGC;COSMIC	6.822	Down-regulation
Atypical_PIKK_FRAP_MTOR_ST	Q9UQ35	SRRM2	P42345	MTOR	T2092	A2095G	2095	Missense	distal	3	no	10.428	10.441	EPSD	ICGC;COSMIC	6.822	Up-regulation
Atypical_PIKK_FRAP_MTOR_ST	Q9UQ35	SRRM2	P42345	MTOR	T2092	R2087L	2087	Missense	distal	-5	no	10.428	10.263	EPSD	ICGC;COSMIC	6.822	Down-regulation
Atypical_PIKK_FRAP_MTOR_ST	Q9UQ35	SRRM2	P42345	MTOR	T2144	Q2150H	2150	Missense	distal	6	no	6.875	6.807	EPSD	ICGC	6.822	Loss
Atypical_PIKK_FRAP_MTOR_ST	Q9UQ35	SRRM2	P42345	MTOR	S2147	Q2150H	2150	Missense	distal	3	no	8.217	9.653	EPSD	ICGC	6.822	Up-regulation
Atypical_PIKK_FRAP_MTOR_ST	Q9UQ35	SRRM2	P42345	MTOR	S2147	G2154S	2154	Missense	distal	7	no	8.217	7.832	EPSD	ICGC;COSMIC	6.822	Down-regulation
Atypical_PIKK_FRAP_MTOR_ST	Q9UQ35	SRRM2	P42345	MTOR	S2171	D2166H	2166	Missense	distal	-5	no	8.742	8.933	EPSD	ICGC;COSMIC	6.822	Up-regulation
Atypical_PIKK_FRAP_MTOR_ST	Q9UQ35	SRRM2	P42345	MTOR	S2171	T2170I	2170	Missense	proximal	-1	no	8.742	8.560	EPSD	ICGC;COSMIC	6.822	Down-regulation
Atypical_PIKK_FRAP_MTOR_ST	Q9UQ35	SRRM2	P42345	MTOR	T2316	A2320S	2320	Missense	distal	4	no	9.459	9.933	EPSD	ICGC	6.822	Up-regulation
Atypical_PIKK_FRAP_MTOR_ST	Q9UQ35	SRRM2	P42345	MTOR	T2329	A2332S	2332	Missense	distal	3	no	7.653	6.598	EPSD	ICGC	6.822	Loss
Atypical_PIKK_FRAP_MTOR_ST	Q9UQ35	SRRM2	P42345	MTOR	T2329	A2332T	2332	Missense	distal	3	no	7.653	6.191	EPSD	ICGC;COSMIC	6.822	Loss
Atypical_PIKK_FRAP_MTOR_ST	Q9UQ35	SRRM2	P42345	MTOR	S2382	A2389S	2389	Missense	distal	7	no	7.948	8.374	EPSD	ICGC	6.822	Up-regulation
Atypical_PIKK_FRAP_MTOR_ST	Q9UQ35	SRRM2	P42345	MTOR	S2398	R2392H	2392	Missense	distal	-6	no	9.346	8.539	EPSD	ICGC;COSMIC;CCLE	6.822	Down-regulation
Atypical_PIKK_FRAP_MTOR_ST	Q9UQ35	SRRM2	P42345	MTOR	S2398	P2400S	2400	Missense	proximal	2	no	9.346	8.852	EPSD	ICGC	6.822	Down-regulation
Atypical_PIKK_FRAP_MTOR_ST	Q9UQ35	SRRM2	P42345	MTOR	S2426	T2420A	2420	Missense	distal	-6	no	9.327	9.048	EPSD	ICGC;COSMIC	6.822	Down-regulation
Atypical_PIKK_FRAP_MTOR_ST	Q9UQ35	SRRM2	P42345	MTOR	S2426	Q2433R	2433	Missense	distal	7	no	9.327	9.726	EPSD	ICGC;COSMIC	6.822	Up-regulation
Atypical_PIKK_FRAP_MTOR_ST	Q9UQ35	SRRM2	P42345	MTOR	S2426	P2427T	2427	Missense	proximal	1	no	9.327	3.055	EPSD	ICGC;COSMIC	6.822	Loss
Atypical_PIKK_FRAP_MTOR_ST	Q9UQ35	SRRM2	P42345	MTOR	S2426	R2430I	2430	Missense	distal	4	no	9.327	9.464	EPSD	ICGC	6.822	Up-regulation
Atypical_PIKK_FRAP_MTOR_ST	Q9UQ35	SRRM2	P42345	MTOR	S2426	M2419I	2419	Missense	distal	-7	no	9.327	8.909	EPSD	ICGC;COSMIC	6.822	Down-regulation
Atypical_PIKK_FRAP_MTOR_ST	Q9UQ35	SRRM2	P42345	MTOR	S2426	T2420I	2420	Missense	distal	-6	no	9.327	8.826	EPSD	ICGC;COSMIC	6.822	Down-regulation
Atypical_PIKK_FRAP_MTOR_ST	Q9UQ35	SRRM2	P42345	MTOR	S2429	R2430I	2430	Missense	proximal	1	no	2.877	7.652	EPSD	ICGC	6.822	Gain
Atypical_PIKK_FRAP_MTOR_ST	Q9UQ35	SRRM2	P42345	MTOR	S2449	P2447A	2447	Missense	proximal	-2	no	12.169	12.375	EPSD	ICGC	6.822	Up-regulation
Atypical_PIKK_FRAP_MTOR_ST	Q9UQ35	SRRM2	P42345	MTOR	S2449	R2448S	2448	Missense	proximal	-1	no	12.169	12.331	EPSD	ICGC	6.822	Up-regulation
Atypical_PIKK_FRAP_MTOR_ST	Q9UQ35	SRRM2	P42345	MTOR	S2545	S2538L	2538	Missense	distal	-7	no	7.702	7.133	EPSD	ICGC	6.822	Down-regulation
Atypical_PIKK_FRAP_MTOR_ST	Q9UQ35	SRRM2	P42345	MTOR	S2545	S2552F	2552	Missense	distal	7	no	7.702	8.283	EPSD	ICGC;COSMIC	6.822	Up-regulation
Atypical_PIKK_FRAP_MTOR_ST	Q9UQ35	SRRM2	P42345	MTOR	S2581	V2579F	2579	Missense	proximal	-2	no	10.090	10.186	EPSD	ICGC	6.822	Up-regulation
Atypical_PIKK_FRAP_MTOR_ST	Q9UQ35	SRRM2	P42345	MTOR	S2581	P2586A	2586	Missense	distal	5	no	10.090	10.404	EPSD	ICGC	6.822	Up-regulation
Atypical_PIKK_FRAP_MTOR_ST	Q9UQ35	SRRM2	P42345	MTOR	S2581	P2584S	2584	Missense	distal	3	no	10.090	10.104	EPSD	ICGC	6.822	Up-regulation
Atypical_PIKK_FRAP_MTOR_ST	Q9UQ35	SRRM2	P42345	MTOR	S2581	P2582H	2582	Missense	proximal	1	no	10.090	-17.101	EPSD	ICGC;COSMIC	6.822	Loss
Atypical_PIKK_FRAP_MTOR_ST	Q9UQ35	SRRM2	P42345	MTOR	S2581	P2586Q	2586	Missense	distal	5	no	10.090	10.161	EPSD	ICGC;COSMIC	6.822	Up-regulation
Atypical_PIKK_FRAP_MTOR_ST	Q9UQ35	SRRM2	P42345	MTOR	S2581	P2580H	2580	Missense	proximal	-1	no	10.090	10.037	EPSD	ICGC;COSMIC	6.822	Down-regulation
Atypical_PIKK_FRAP_MTOR_ST	Q9UQ35	SRRM2	P42345	MTOR	S2581	A2585S	2585	Missense	distal	4	no	10.090	10.564	EPSD	ICGC;COSMIC	6.822	Up-regulation
Atypical_PIKK_FRAP_MTOR_ST	Q9UQ35	SRRM2	P42345	MTOR	T2583	V2579F	2579	Missense	distal	-4	no	8.259	8.966	EPSD	ICGC	6.822	Up-regulation
Atypical_PIKK_FRAP_MTOR_ST	Q9UQ35	SRRM2	P42345	MTOR	T2583	A2589S	2589	Missense	distal	6	no	8.259	8.909	EPSD	ICGC	6.822	Up-regulation
Atypical_PIKK_FRAP_MTOR_ST	Q9UQ35	SRRM2	P42345	MTOR	T2583	P2586A	2586	Missense	distal	3	no	8.259	9.328	EPSD	ICGC	6.822	Up-regulation
Atypical_PIKK_FRAP_MTOR_ST	Q9UQ35	SRRM2	P42345	MTOR	T2583	P2584S	2584	Missense	proximal	1	no	8.259	-0.265	EPSD	ICGC	6.822	Loss
Atypical_PIKK_FRAP_MTOR_ST	Q9UQ35	SRRM2	P42345	MTOR	T2583	P2582H	2582	Missense	proximal	-1	no	8.259	8.206	EPSD	ICGC;COSMIC	6.822	Down-regulation
Atypical_PIKK_FRAP_MTOR_ST	Q9UQ35	SRRM2	P42345	MTOR	T2583	P2586Q	2586	Missense	distal	3	no	8.259	6.727	EPSD	ICGC;COSMIC	6.822	Loss
Atypical_PIKK_FRAP_MTOR_ST	Q9UQ35	SRRM2	P42345	MTOR	T2583	P2580H	2580	Missense	distal	-3	no	8.259	8.290	EPSD	ICGC;COSMIC	6.822	Up-regulation
Atypical_PIKK_FRAP_MTOR_ST	Q9UQ35	SRRM2	P42345	MTOR	T2583	A2585S	2585	Missense	proximal	2	no	8.259	9.022	EPSD	ICGC;COSMIC	6.822	Up-regulation
Atypical_PIKK_FRAP_MTOR_ST	Q9UQ35	SRRM2	P42345	MTOR	T2599	R2606C	2606	Missense	distal	7	no	6.422	6.852	EPSD	ICGC;COSMIC	6.822	Gain
Atypical_PIKK_FRAP_MTOR_ST	Q9UQ35	SRRM2	P42345	MTOR	S2650	K2653N	2653	Missense	distal	3	no	10.432	11.267	EPSD	ICGC;COSMIC	6.822	Up-regulation
Atypical_PIKK_FRAP_MTOR_ST	Q9UQ35	SRRM2	P42345	MTOR	S2690	R2689W	2689	Missense	proximal	-1	no	7.804	7.877	EPSD	ICGC;COSMIC	6.822	Up-regulation
Atypical_PIKK_FRAP_MTOR_ST	Q9UQ35	SRRM2	P42345	MTOR	S2690	E2697G	2697	Missense	distal	7	no	7.804	8.639	EPSD	ICGC;COSMIC	6.822	Up-regulation
Atypical_PIKK_FRAP_MTOR_ST	Q9UQ35	SRRM2	P42345	MTOR	S2694	R2689W	2689	Missense	distal	-5	no	10.965	11.022	EPSD	ICGC;COSMIC	6.822	Up-regulation
Atypical_PIKK_FRAP_MTOR_ST	Q9UQ35	SRRM2	P42345	MTOR	S2694	R2699L	2699	Missense	distal	5	no	10.965	11.459	EPSD	ICGC	6.822	Up-regulation
Atypical_PIKK_FRAP_MTOR_ST	Q9UQ35	SRRM2	P42345	MTOR	S2694	E2697G	2697	Missense	distal	3	no	10.965	11.780	EPSD	ICGC;COSMIC	6.822	Up-regulation
Atypical_PIKK_FRAP_MTOR_ST	Q9UQ35	SRRM2	P42345	MTOR	S2702	D2709Y	2709	Missense	distal	7	no	7.488	6.527	EPSD	ICGC	6.822	Loss
Atypical_PIKK_FRAP_MTOR_ST	Q9UQ35	SRRM2	P42345	MTOR	S2702	R2699L	2699	Missense	distal	-3	no	7.488	7.557	EPSD	ICGC	6.822	Up-regulation
Atypical_PIKK_FRAP_MTOR_ST	Q9UQ35	SRRM2	P42345	MTOR	S2702	R2708W	2708	Missense	distal	6	no	7.488	8.019	EPSD	ICGC	6.822	Up-regulation
Atypical_PIKK_FRAP_MTOR_ST	Q9UQ35	SRRM2	P42345	MTOR	S2702	E2697G	2697	Missense	distal	-5	no	7.488	7.862	EPSD	ICGC;COSMIC	6.822	Up-regulation
Atypical_PIKK_FRAP_MTOR_ST	Q9UQ35	SRRM2	P42345	MTOR	S2706	D2709Y	2709	Missense	distal	3	no	7.986	7.520	EPSD	ICGC	6.822	Down-regulation
Atypical_PIKK_FRAP_MTOR_ST	Q9UQ35	SRRM2	P42345	MTOR	S2706	R2699L	2699	Missense	distal	-7	no	7.986	8.175	EPSD	ICGC	6.822	Up-regulation
Atypical_PIKK_FRAP_MTOR_ST	Q9UQ35	SRRM2	P42345	MTOR	S2706	R2708W	2708	Missense	proximal	2	no	7.986	8.877	EPSD	ICGC	6.822	Up-regulation
Atypical_PIKK_FRAP_MTOR_ST	Q9UQ35	SRRM2	P42345	MTOR	S2712	R2717W	2717	Missense	distal	5	no	7.479	6.496	EPSD	ICGC;COSMIC	6.822	Loss
Atypical_PIKK_FRAP_MTOR_ST	Q9UQ35	SRRM2	P42345	MTOR	S2712	D2709Y	2709	Missense	distal	-3	no	7.479	7.593	EPSD	ICGC	6.822	Up-regulation
Atypical_PIKK_FRAP_MTOR_ST	Q9UQ35	SRRM2	P42345	MTOR	S2712	R2708W	2708	Missense	distal	-4	no	7.479	7.589	EPSD	ICGC	6.822	Up-regulation
Atypical_PIKK_FRAP_MTOR_ST	Q9UQ35	SRRM2	P42345	MTOR	T2738	R2742W	2742	Missense	distal	4	no	14.945	15.107	EPSD	ICGC;COSMIC	6.822	Up-regulation
Atypical_PIKK_FRAP_MTOR_ST	Q9UQ35	SRRM2	P42345	MTOR	S2740	R2742W	2742	Missense	proximal	2	no	15.970	16.862	EPSD	ICGC;COSMIC	6.822	Up-regulation
Atypical_PIKK_FRAP_MTOR_ST	Q9UQ35	SRRM2	P42345	MTOR	S2748	R2750S	2750	Missense	proximal	2	no	5.337	7.049	EPSD	ICGC	6.822	Gain
Atypical_PIKK_FRAP_MTOR_ST	Q9UQ35	SRRM2	P42345	MTOR	S2749	R2750S	2750	Missense	proximal	1	no	6.315	7.624	EPSD	ICGC	6.822	Gain
Atypical_PIKK_FRAP_MTOR_ST	Q9UQ35	SRRM2	P42345	MTOR	S2751	R2750S	2750	Missense	proximal	-1	no	13.770	13.932	EPSD	ICGC	6.822	Up-regulation
Atypical_PIKK_FRAP_MTOR_ST	P42345	MTOR	P42345	MTOR	T314	A321V	321	Missense	distal	7	no	9.077	10.015	EPSD	ICGC	6.822	Up-regulation
Atypical_PIKK_FRAP_MTOR_ST	P42345	MTOR	P42345	MTOR	S1166	S1166R	1166	Missense	central	0	yes	8.242	0.000	EPSD	ICGC;COSMIC	6.822	Loss
Atypical_PIKK_FRAP_MTOR_ST	P42345	MTOR	P42345	MTOR	S1166	A1173G	1173	Missense	distal	7	no	8.242	9.052	EPSD	ICGC;COSMIC	6.822	Up-regulation
Atypical_PIKK_FRAP_MTOR_ST	P42345	MTOR	P42345	MTOR	S1166	V1160G	1160	Missense	distal	-6	no	8.242	8.986	EPSD	ICGC;COSMIC	6.822	Up-regulation
Atypical_PIKK_FRAP_MTOR_ST	P42345	MTOR	P42345	MTOR	S1179	A1173G	1173	Missense	distal	-6	no	6.669	7.128	EPSD	ICGC;COSMIC	6.822	Gain
Atypical_PIKK_FRAP_MTOR_ST	P42345	MTOR	P42345	MTOR	S1297	C1303F	1303	Missense	distal	6	no	8.086	9.206	EPSD	ICGC;COSMIC	6.822	Up-regulation
Atypical_PIKK_FRAP_MTOR_ST	P42345	MTOR	P42345	MTOR	S1297	W1304R	1304	Missense	distal	7	no	8.086	8.472	EPSD	ICGC;COSMIC;GDSC;CCLE	6.822	Up-regulation
Atypical_PIKK_FRAP_MTOR_ST	P42345	MTOR	P42345	MTOR	S1297	R1301L	1301	Missense	distal	4	no	8.086	8.019	EPSD	ICGC;COSMIC	6.822	Down-regulation
Atypical_PIKK_FRAP_MTOR_ST	P42345	MTOR	P42345	MTOR	S1297	R1301H	1301	Missense	distal	4	no	8.086	7.827	EPSD	ICGC;COSMIC	6.822	Down-regulation
Atypical_PIKK_FRAP_MTOR_ST	P42345	MTOR	P42345	MTOR	S1297	C1303R	1303	Missense	distal	6	no	8.086	7.959	EPSD	ICGC;COSMIC	6.822	Down-regulation
Atypical_PIKK_FRAP_MTOR_ST	P42345	MTOR	P42345	MTOR	S1843	N1848K	1848	Missense	distal	5	no	7.462	5.652	EPSD	ICGC	6.822	Loss
Atypical_PIKK_FRAP_MTOR_ST	P42345	MTOR	P42345	MTOR	T1948	P1951H	1951	Missense	distal	3	no	10.116	10.020	EPSD	ICGC	6.822	Down-regulation
Atypical_PIKK_FRAP_MTOR_ST	P42345	MTOR	P42345	MTOR	S2221	S2215T	2215	Missense	distal	-6	no	8.517	8.459	EPSD	ICGC;COSMIC	6.822	Down-regulation
Atypical_PIKK_FRAP_MTOR_ST	P42345	MTOR	P42345	MTOR	S2221	Q2223L	2223	Missense	proximal	2	no	8.517	10.047	EPSD	ICGC;COSMIC	6.822	Up-regulation
Atypical_PIKK_FRAP_MTOR_ST	P42345	MTOR	P42345	MTOR	S2448	R2445S	2445	Missense	distal	-3	no	6.949	6.603	EPSD	ICGC;COSMIC	6.822	Loss
Atypical_PIKK_FRAP_MTOR_ST	P42345	MTOR	P42345	MTOR	S2454	E2456K	2456	Missense	proximal	2	no	7.693	6.788	PhosphoSitePlus;EPSD	ICGC;COSMIC	6.822	Loss
Atypical_PIKK_FRAP_MTOR_ST	P42345	MTOR	P42345	MTOR	T2474	E2477Q	2477	Missense	distal	3	no	7.756	5.958	EPSD;PhosphoSitePlus	ICGC;COSMIC	6.822	Loss
Atypical_PIKK_FRAP_MTOR_ST	P42345	MTOR	P42345	MTOR	T2474	A2467D	2467	Missense	distal	-7	no	7.756	8.841	EPSD;PhosphoSitePlus	ICGC	6.822	Up-regulation
Atypical_PIKK_FRAP_MTOR_ST	P42345	MTOR	P42345	MTOR	S2478	E2477Q	2477	Missense	proximal	-1	no	7.854	7.743	EPSD;PhosphoSitePlus	ICGC;COSMIC	6.822	Down-regulation
Atypical_PIKK_FRAP_MTOR_ST	P42345	MTOR	P42345	MTOR	S2478	D2485E	2485	Missense	distal	7	no	7.854	6.842	EPSD;PhosphoSitePlus	ICGC	6.822	Down-regulation
Atypical_PIKK_FRAP_MTOR_ST	P42345	MTOR	P42345	MTOR	S2481	E2477Q	2477	Missense	distal	-4	no	8.388	8.126	EPSD;PhosphoSitePlus	ICGC;COSMIC	6.822	Down-regulation
Atypical_PIKK_FRAP_MTOR_ST	P42345	MTOR	P42345	MTOR	S2481	D2485E	2485	Missense	distal	4	no	8.388	8.226	EPSD;PhosphoSitePlus	ICGC	6.822	Down-regulation
Atypical_PIKK_FRAP_MTOR_ST	P42345	MTOR	P42345	MTOR	S2481	L2487V	2487	Missense	distal	6	no	8.388	9.618	EPSD;PhosphoSitePlus	ICGC	6.822	Up-regulation
Atypical_PIKK_FRAP_MTOR_ST	P42345	MTOR	P42345	MTOR	S2481	G2486S	2486	Missense	distal	5	no	8.388	7.725	EPSD;PhosphoSitePlus	ICGC;COSMIC	6.822	Down-regulation
Atypical_PIKK_FRAP_MTOR_ST	P55199	ELL	P42345	MTOR	S47	L50Q	50	Missense	distal	3	no	6.281	7.004	EPSD	ICGC;COSMIC	6.822	Gain
Atypical_PIKK_FRAP_MTOR_ST	P55199	ELL	P42345	MTOR	S47	A43D	43	Missense	distal	-4	no	6.281	8.273	EPSD	ICGC;COSMIC	6.822	Gain
Atypical_PIKK_FRAP_MTOR_ST	P55199	ELL	P42345	MTOR	T368	P367H	367	Missense	proximal	-1	no	10.560	10.507	EPSD	ICGC	6.822	Down-regulation
Atypical_PIKK_FRAP_MTOR_ST	P55199	ELL	P42345	MTOR	T368	P367S	367	Missense	proximal	-1	no	10.560	10.628	EPSD	ICGC;COSMIC	6.822	Up-regulation
Atypical_PIKK_FRAP_MTOR_ST	P55199	ELL	P42345	MTOR	S442	K449R	449	Missense	distal	7	no	8.058	9.204	EPSD	ICGC;COSMIC	6.822	Up-regulation
Atypical_PIKK_FRAP_MTOR_ST	O75385	ULK1	P42345	MTOR	S287	P293L	293	Missense	distal	6	no	8.168	7.009	EPSD	ICGC	6.822	Down-regulation
Atypical_PIKK_FRAP_MTOR_ST	O75385	ULK1	P42345	MTOR	S287	P289T	289	Missense	proximal	2	no	8.168	7.615	EPSD	ICGC;COSMIC	6.822	Down-regulation
Atypical_PIKK_FRAP_MTOR_ST	O75385	ULK1	P42345	MTOR	S307	G301V	301	Missense	distal	-6	no	7.409	6.665	EPSD	ICGC	6.822	Loss
Atypical_PIKK_FRAP_MTOR_ST	O75385	ULK1	P42345	MTOR	S314	P315T	315	Missense	proximal	1	no	10.170	3.898	EPSD	ICGC;COSMIC	6.822	Loss
Atypical_PIKK_FRAP_MTOR_ST	O75385	ULK1	P42345	MTOR	S405	G399C	399	Missense	distal	-6	no	7.192	7.305	EPSD	ICGC;COSMIC	6.822	Up-regulation
Atypical_PIKK_FRAP_MTOR_ST	O75385	ULK1	P42345	MTOR	S405	P404S	404	Missense	proximal	-1	no	7.192	7.261	EPSD	ICGC;COSMIC;GDSC;CCLE	6.822	Up-regulation
Atypical_PIKK_FRAP_MTOR_ST	O75385	ULK1	P42345	MTOR	S405	P402Q	402	Missense	distal	-3	no	7.192	7.362	EPSD	ICGC;COSMIC	6.822	Up-regulation
Atypical_PIKK_FRAP_MTOR_ST	O75385	ULK1	P42345	MTOR	S405	P412H	412	Missense	distal	7	no	7.192	7.807	EPSD	ICGC;COSMIC	6.822	Up-regulation
Atypical_PIKK_FRAP_MTOR_ST	O75385	ULK1	P42345	MTOR	S409	P414L	414	Missense	distal	5	no	6.979	8.352	EPSD	ICGC	6.822	Up-regulation
Atypical_PIKK_FRAP_MTOR_ST	O75385	ULK1	P42345	MTOR	S409	P404S	404	Missense	distal	-5	no	6.979	6.931	EPSD	ICGC;COSMIC;GDSC;CCLE	6.822	Down-regulation
Atypical_PIKK_FRAP_MTOR_ST	O75385	ULK1	P42345	MTOR	S409	P402Q	402	Missense	distal	-7	no	6.979	6.580	EPSD	ICGC;COSMIC	6.822	Loss
Atypical_PIKK_FRAP_MTOR_ST	O75385	ULK1	P42345	MTOR	S409	P412H	412	Missense	distal	3	no	6.979	6.884	EPSD	ICGC;COSMIC	6.822	Down-regulation
Atypical_PIKK_FRAP_MTOR_ST	O75385	ULK1	P42345	MTOR	S409	G416C	416	Missense	distal	7	no	6.979	7.817	EPSD	ICGC;COSMIC	6.822	Up-regulation
Atypical_PIKK_FRAP_MTOR_ST	O75385	ULK1	P42345	MTOR	S410	P414L	414	Missense	distal	4	no	7.123	6.739	EPSD	ICGC	6.822	Loss
Atypical_PIKK_FRAP_MTOR_ST	O75385	ULK1	P42345	MTOR	S410	P404S	404	Missense	distal	-6	no	7.123	7.102	EPSD	ICGC;COSMIC;GDSC;CCLE	6.822	Down-regulation
Atypical_PIKK_FRAP_MTOR_ST	O75385	ULK1	P42345	MTOR	S410	P412H	412	Missense	proximal	2	no	7.123	4.538	EPSD	ICGC;COSMIC	6.822	Loss
Atypical_PIKK_FRAP_MTOR_ST	O75385	ULK1	P42345	MTOR	S410	G416C	416	Missense	distal	6	no	7.123	5.497	EPSD	ICGC;COSMIC	6.822	Loss
Atypical_PIKK_FRAP_MTOR_ST	O75385	ULK1	P42345	MTOR	S411	P414L	414	Missense	distal	3	no	9.285	7.031	EPSD	ICGC	6.822	Down-regulation
Atypical_PIKK_FRAP_MTOR_ST	O75385	ULK1	P42345	MTOR	S411	P404S	404	Missense	distal	-7	no	9.285	9.722	EPSD	ICGC;COSMIC;GDSC;CCLE	6.822	Up-regulation
Atypical_PIKK_FRAP_MTOR_ST	O75385	ULK1	P42345	MTOR	S411	P412H	412	Missense	proximal	1	no	9.285	-17.906	EPSD	ICGC;COSMIC	6.822	Loss
Atypical_PIKK_FRAP_MTOR_ST	O75385	ULK1	P42345	MTOR	S411	G416C	416	Missense	distal	5	no	9.285	9.400	EPSD	ICGC;COSMIC	6.822	Up-regulation
Atypical_PIKK_FRAP_MTOR_ST	O75385	ULK1	P42345	MTOR	S413	P414L	414	Missense	proximal	1	no	12.999	7.029	EPSD	ICGC	6.822	Down-regulation
Atypical_PIKK_FRAP_MTOR_ST	O75385	ULK1	P42345	MTOR	S413	P412H	412	Missense	proximal	-1	no	12.999	12.946	EPSD	ICGC;COSMIC	6.822	Down-regulation
Atypical_PIKK_FRAP_MTOR_ST	O75385	ULK1	P42345	MTOR	S413	G416C	416	Missense	distal	3	no	12.999	9.164	EPSD	ICGC;COSMIC	6.822	Down-regulation
Atypical_PIKK_FRAP_MTOR_ST	O75385	ULK1	P42345	MTOR	S450	T452I	452	Missense	proximal	2	no	8.493	8.505	EPSD	ICGC;COSMIC	6.822	Up-regulation
Atypical_PIKK_FRAP_MTOR_ST	O75385	ULK1	P42345	MTOR	S479	E485V	485	Missense	distal	6	no	10.447	10.319	EPSD	ICGC;COSMIC	6.822	Down-regulation
Atypical_PIKK_FRAP_MTOR_ST	O75385	ULK1	P42345	MTOR	T503	V508G	508	Missense	distal	5	no	8.319	7.859	EPSD	ICGC;COSMIC	6.822	Down-regulation
Atypical_PIKK_FRAP_MTOR_ST	O75385	ULK1	P42345	MTOR	T503	P501H	501	Missense	proximal	-2	no	8.319	7.604	EPSD	ICGC;COSMIC	6.822	Down-regulation
Atypical_PIKK_FRAP_MTOR_ST	O75385	ULK1	P42345	MTOR	S505	V508G	508	Missense	distal	3	no	5.594	7.618	EPSD	ICGC;COSMIC	6.822	Gain
Atypical_PIKK_FRAP_MTOR_ST	O75385	ULK1	P42345	MTOR	T510	V508G	508	Missense	proximal	-2	no	8.039	8.686	EPSD	ICGC;COSMIC	6.822	Up-regulation
Atypical_PIKK_FRAP_MTOR_ST	O75385	ULK1	P42345	MTOR	T520	E527D	527	Missense	distal	7	no	10.741	11.752	EPSD	ICGC	6.822	Up-regulation
Atypical_PIKK_FRAP_MTOR_ST	O75385	ULK1	P42345	MTOR	T520	T520M	520	Missense	central	0	yes	10.741	0.000	EPSD	ICGC	6.822	Loss
Atypical_PIKK_FRAP_MTOR_ST	O75385	ULK1	P42345	MTOR	T520	G519W	519	Missense	proximal	-1	no	10.741	10.658	EPSD	ICGC;COSMIC	6.822	Down-regulation
Atypical_PIKK_FRAP_MTOR_ST	O75385	ULK1	P42345	MTOR	S522	E527D	527	Missense	distal	5	no	12.786	13.204	EPSD	ICGC	6.822	Up-regulation
Atypical_PIKK_FRAP_MTOR_ST	O75385	ULK1	P42345	MTOR	S522	T520M	520	Missense	proximal	-2	no	12.786	12.198	EPSD	ICGC	6.822	Down-regulation
Atypical_PIKK_FRAP_MTOR_ST	O75385	ULK1	P42345	MTOR	S522	G519W	519	Missense	distal	-3	no	12.786	12.545	EPSD	ICGC;COSMIC	6.822	Down-regulation
Atypical_PIKK_FRAP_MTOR_ST	O75385	ULK1	P42345	MTOR	S544	G551V	551	Missense	distal	7	no	7.935	8.063	EPSD	ICGC	6.822	Up-regulation
Atypical_PIKK_FRAP_MTOR_ST	O75385	ULK1	P42345	MTOR	S583	P589H	589	Missense	distal	6	no	9.447	7.971	EPSD	ICGC;COSMIC	6.822	Down-regulation
Atypical_PIKK_FRAP_MTOR_ST	O75385	ULK1	P42345	MTOR	S583	P584L	584	Missense	proximal	1	no	9.447	3.478	EPSD	ICGC;COSMIC	6.822	Loss
Atypical_PIKK_FRAP_MTOR_ST	O75385	ULK1	P42345	MTOR	S583	L578M	578	Missense	distal	-5	no	9.447	9.465	EPSD	ICGC;COSMIC	6.822	Up-regulation
Atypical_PIKK_FRAP_MTOR_ST	O75385	ULK1	P42345	MTOR	S583	P577H	577	Missense	distal	-6	no	9.447	8.727	EPSD	ICGC;COSMIC	6.822	Down-regulation
Atypical_PIKK_FRAP_MTOR_ST	O75385	ULK1	P42345	MTOR	S623	S630Y	630	Missense	distal	7	no	10.840	10.441	EPSD	ICGC;COSMIC	6.822	Down-regulation
Atypical_PIKK_FRAP_MTOR_ST	O75385	ULK1	P42345	MTOR	S623	P624H	624	Missense	proximal	1	no	10.840	-16.351	EPSD	ICGC;COSMIC	6.822	Loss
Atypical_PIKK_FRAP_MTOR_ST	O75385	ULK1	P42345	MTOR	T636	S630Y	630	Missense	distal	-6	no	14.602	13.732	EPSD	ICGC;COSMIC	6.822	Down-regulation
Atypical_PIKK_FRAP_MTOR_ST	O75385	ULK1	P42345	MTOR	T654	R657L	657	Missense	distal	3	no	9.678	7.689	EPSD	ICGC	6.822	Down-regulation
Atypical_PIKK_FRAP_MTOR_ST	O75385	ULK1	P42345	MTOR	S748	G744E	744	Missense	distal	-4	no	14.773	15.219	EPSD	ICGC;COSMIC	6.822	Up-regulation
Atypical_PIKK_FRAP_MTOR_ST	O75385	ULK1	P42345	MTOR	S748	V753F	753	Missense	distal	5	no	14.773	14.237	EPSD	ICGC	6.822	Down-regulation
Atypical_PIKK_FRAP_MTOR_ST	O75385	ULK1	P42345	MTOR	S748	P751L	751	Missense	distal	3	no	14.773	12.518	EPSD	ICGC;COSMIC	6.822	Down-regulation
Atypical_PIKK_FRAP_MTOR_ST	O75385	ULK1	P42345	MTOR	S748	R742L	742	Missense	distal	-6	no	14.773	13.911	EPSD	ICGC;COSMIC	6.822	Down-regulation
Atypical_PIKK_FRAP_MTOR_ST	O75385	ULK1	P42345	MTOR	S748	R742C	742	Missense	distal	-6	no	14.773	14.899	EPSD	ICGC;COSMIC	6.822	Up-regulation
Atypical_PIKK_FRAP_MTOR_ST	O75385	ULK1	P42345	MTOR	S750	G744E	744	Missense	distal	-6	no	9.069	8.863	EPSD	ICGC;COSMIC	6.822	Down-regulation
Atypical_PIKK_FRAP_MTOR_ST	O75385	ULK1	P42345	MTOR	S750	V753F	753	Missense	distal	3	no	9.069	10.430	EPSD	ICGC	6.822	Up-regulation
Atypical_PIKK_FRAP_MTOR_ST	O75385	ULK1	P42345	MTOR	S750	P751L	751	Missense	proximal	1	no	9.069	3.100	EPSD	ICGC;COSMIC	6.822	Loss
Atypical_PIKK_FRAP_MTOR_ST	O75385	ULK1	P42345	MTOR	S758	P759L	759	Missense	proximal	1	no	11.865	5.896	PhosphoSitePlus;EPSD	ICGC	6.822	Loss
Atypical_PIKK_FRAP_MTOR_ST	O75385	ULK1	P42345	MTOR	S758	P759F	759	Missense	proximal	1	no	11.865	5.344	PhosphoSitePlus;EPSD	ICGC	6.822	Loss
Atypical_PIKK_FRAP_MTOR_ST	O75385	ULK1	P42345	MTOR	S758	P759S	759	Missense	proximal	1	no	11.865	3.341	PhosphoSitePlus;EPSD	ICGC;COSMIC	6.822	Loss
Atypical_PIKK_FRAP_MTOR_ST	O75385	ULK1	P42345	MTOR	S758	V753F	753	Missense	distal	-5	no	11.865	11.934	PhosphoSitePlus;EPSD	ICGC	6.822	Up-regulation
Atypical_PIKK_FRAP_MTOR_ST	O75385	ULK1	P42345	MTOR	S758	P751L	751	Missense	distal	-7	no	11.865	11.732	PhosphoSitePlus;EPSD	ICGC;COSMIC	6.822	Down-regulation
Atypical_PIKK_FRAP_MTOR_ST	O75385	ULK1	P42345	MTOR	S758	P765S	765	Missense	distal	7	no	11.865	11.844	PhosphoSitePlus;EPSD	ICGC	6.822	Down-regulation
Atypical_PIKK_FRAP_MTOR_ST	Q9H8M2	BRD9	P42345	MTOR	S588	A592V	592	Missense	distal	4	no	19.616	19.778	PhosphoSitePlus	ICGC;COSMIC;CCLE	6.822	Up-regulation
Atypical_PIKK_FRAP_MTOR_ST	Q9H8M2	BRD9	P42345	MTOR	S588	A595D	595	Missense	distal	7	no	19.616	20.604	PhosphoSitePlus	ICGC	6.822	Up-regulation
Atypical_PIKK_FRAP_MTOR_ST	Q9H8M2	BRD9	P42345	MTOR	S594	A592V	592	Missense	proximal	-2	no	9.543	9.064	EPSD	ICGC;COSMIC;CCLE	6.822	Down-regulation
Atypical_PIKK_FRAP_MTOR_ST	Q9H8M2	BRD9	P42345	MTOR	S594	A595D	595	Missense	proximal	1	no	9.543	9.406	EPSD	ICGC	6.822	Down-regulation
Atypical_PIKK_FRAP_MTOR_ST	Q9H8M2	BRD9	P42345	MTOR	T597	A592V	592	Missense	distal	-5	no	7.148	7.059	EPSD	ICGC;COSMIC;CCLE	6.822	Down-regulation
Atypical_PIKK_FRAP_MTOR_ST	Q9H8M2	BRD9	P42345	MTOR	T597	A595D	595	Missense	proximal	-2	no	7.148	6.263	EPSD	ICGC	6.822	Loss
Atypical_PIKK_FRAP_MTOR_ST	P23443	RPS6KB1	P42345	MTOR	S434	S441N	441	Missense	distal	7	no	11.217	11.816	EPSD;PhosphoSitePlus	ICGC;COSMIC	6.822	Up-regulation
Atypical_PIKK_FRAP_MTOR_ST	P23443	RPS6KB1	P42345	MTOR	S441	P445T	445	Missense	distal	4	no	9.365	9.689	EPSD	ICGC;COSMIC	6.822	Up-regulation
Atypical_PIKK_FRAP_MTOR_ST	P23443	RPS6KB1	P42345	MTOR	S441	S441N	441	Missense	central	0	yes	9.365	0.000	EPSD	ICGC;COSMIC	6.822	Loss
Atypical_PIKK_FRAP_MTOR_ST	P23443	RPS6KB1	P42345	MTOR	T444	P445T	445	Missense	proximal	1	no	9.326	3.054	EPSD	ICGC;COSMIC	6.822	Loss
Atypical_PIKK_FRAP_MTOR_ST	P23443	RPS6KB1	P42345	MTOR	T444	S441N	441	Missense	distal	-3	no	9.326	9.876	EPSD	ICGC;COSMIC	6.822	Up-regulation
Atypical_PIKK_FRAP_MTOR_ST	P23443	RPS6KB1	P42345	MTOR	S447	P445T	445	Missense	proximal	-2	no	9.793	9.501	EPSD	ICGC;COSMIC	6.822	Down-regulation
Atypical_PIKK_FRAP_MTOR_ST	P23443	RPS6KB1	P42345	MTOR	S447	S441N	441	Missense	distal	-6	no	9.793	9.106	EPSD	ICGC;COSMIC	6.822	Down-regulation
Atypical_PIKK_FRAP_MTOR_ST	P23443	RPS6KB1	P42345	MTOR	S452	P445T	445	Missense	distal	-7	no	7.565	8.053	EPSD	ICGC;COSMIC	6.822	Up-regulation
Atypical_PIKK_FRAP_MTOR_ST	P03372	ESR1	P42345	MTOR	S104	P99S	99	Missense	distal	-5	no	9.917	9.869	EPSD;PhosphoSitePlus	ICGC	6.822	Down-regulation
Atypical_PIKK_FRAP_MTOR_ST	P03372	ESR1	P42345	MTOR	S104	S102N	102	Missense	proximal	-2	no	9.917	9.326	EPSD;PhosphoSitePlus	ICGC;COSMIC	6.822	Down-regulation
Atypical_PIKK_FRAP_MTOR_ST	P03372	ESR1	P42345	MTOR	S104	N101S	101	Missense	distal	-3	no	9.917	9.368	EPSD;PhosphoSitePlus	ICGC;COSMIC	6.822	Down-regulation
Atypical_PIKK_FRAP_MTOR_ST	P03372	ESR1	P42345	MTOR	S106	P99S	99	Missense	distal	-7	no	8.413	8.850	PhosphoSitePlus;EPSD	ICGC	6.822	Up-regulation
Atypical_PIKK_FRAP_MTOR_ST	P03372	ESR1	P42345	MTOR	S106	S102N	102	Missense	distal	-4	no	8.413	7.281	PhosphoSitePlus;EPSD	ICGC;COSMIC	6.822	Down-regulation
Atypical_PIKK_FRAP_MTOR_ST	P03372	ESR1	P42345	MTOR	S106	N101S	101	Missense	distal	-5	no	8.413	8.502	PhosphoSitePlus;EPSD	ICGC;COSMIC	6.822	Up-regulation
Atypical_PIKK_FRAP_MTOR_ST	P03372	ESR1	P42345	MTOR	S106	H112P	112	Missense	distal	6	no	8.413	9.889	PhosphoSitePlus;EPSD	ICGC;COSMIC	6.822	Up-regulation
Atypical_PIKK_FRAP_MTOR_ST	P03372	ESR1	P42345	MTOR	S341	S341L	341	Missense	central	0	yes	10.280	0.000	EPSD	ICGC;COSMIC;GDSC;CCLE	6.822	Loss
Atypical_PIKK_FRAP_MTOR_ST	P03372	ESR1	P42345	MTOR	S341	P336A	336	Missense	distal	-5	no	10.280	10.259	EPSD	ICGC;COSMIC	6.822	Down-regulation
Atypical_PIKK_FRAP_MTOR_ST	P03372	ESR1	P42345	MTOR	S559	R555L	555	Missense	distal	-4	no	8.025	7.596	EPSD	ICGC	6.822	Down-regulation
Atypical_PIKK_FRAP_MTOR_ST	Q9P2Y5	UVRAG	P42345	MTOR	T518	S525L	525	Missense	distal	7	no	10.015	10.993	EPSD	ICGC;COSMIC	6.822	Up-regulation
Atypical_PIKK_FRAP_MTOR_ST	Q9P2Y5	UVRAG	P42345	MTOR	T518	P520H	520	Missense	proximal	2	no	10.015	7.430	EPSD	ICGC;COSMIC	6.822	Down-regulation
Atypical_PIKK_FRAP_MTOR_ST	Q9P2Y5	UVRAG	P42345	MTOR	S696	R694C	694	Missense	proximal	-2	no	9.716	9.993	EPSD	ICGC;COSMIC	6.822	Up-regulation
Atypical_PIKK_FRAP_MTOR_ST	Q9P2Y5	UVRAG	P42345	MTOR	S696	R692L	692	Missense	distal	-4	no	9.716	9.286	EPSD	ICGC;COSMIC	6.822	Down-regulation
Atypical_PIKK_FRAP_MTOR_ST	P19484	TFEB	P42345	MTOR	T50	V57I	57	Missense	distal	7	no	8.817	8.679	EPSD	ICGC;COSMIC	6.822	Down-regulation
Atypical_PIKK_FRAP_MTOR_ST	P19484	TFEB	P42345	MTOR	T55	Q60H	60	Missense	distal	5	no	6.065	7.177	EPSD	ICGC	6.822	Gain
Atypical_PIKK_FRAP_MTOR_ST	P19484	TFEB	P42345	MTOR	S109	P115Q	115	Missense	distal	6	no	8.510	7.102	EPSD	ICGC;COSMIC	6.822	Down-regulation
Atypical_PIKK_FRAP_MTOR_ST	P19484	TFEB	P42345	MTOR	S114	A121D	121	Missense	distal	7	no	8.733	9.721	EPSD	ICGC;COSMIC	6.822	Up-regulation
Atypical_PIKK_FRAP_MTOR_ST	P19484	TFEB	P42345	MTOR	S114	P115Q	115	Missense	proximal	1	no	8.733	0.119	EPSD	ICGC;COSMIC	6.822	Loss
Atypical_PIKK_FRAP_MTOR_ST	P19484	TFEB	P42345	MTOR	S122	A121D	121	Missense	proximal	-1	no	9.332	9.276	PhosphoSitePlus;EPSD	ICGC;COSMIC	6.822	Down-regulation
Atypical_PIKK_FRAP_MTOR_ST	P19484	TFEB	P42345	MTOR	S122	P115Q	115	Missense	distal	-7	no	9.332	8.932	PhosphoSitePlus;EPSD	ICGC;COSMIC	6.822	Down-regulation
Atypical_PIKK_FRAP_MTOR_ST	P19484	TFEB	P42345	MTOR	S122	H129N	129	Missense	distal	7	no	9.332	9.295	PhosphoSitePlus;EPSD	ICGC	6.822	Down-regulation
Atypical_PIKK_FRAP_MTOR_ST	P19484	TFEB	P42345	MTOR	S211	S211F	211	Missense	central	0	yes	8.216	0.000	EPSD;PhosphoSitePlus	ICGC;COSMIC	6.822	Loss
Atypical_PIKK_FRAP_MTOR_ST	P19484	TFEB	P42345	MTOR	S211	S210F	210	Missense	proximal	-1	no	8.216	8.032	EPSD;PhosphoSitePlus	ICGC;COSMIC	6.822	Down-regulation
Atypical_PIKK_FRAP_MTOR_ST	P19484	TFEB	P42345	MTOR	S211	D215E	215	Missense	distal	4	no	8.216	8.055	EPSD;PhosphoSitePlus	ICGC	6.822	Down-regulation
Atypical_PIKK_FRAP_MTOR_ST	P19484	TFEB	P42345	MTOR	S211	T208A	208	Missense	distal	-3	no	8.216	8.162	EPSD;PhosphoSitePlus	ICGC;COSMIC	6.822	Down-regulation
Atypical_PIKK_FRAP_MTOR_ST	P19484	TFEB	P42345	MTOR	S462	R464H	464	Missense	proximal	2	no	10.081	9.703	EPSD	ICGC;COSMIC	6.822	Down-regulation
Atypical_PIKK_FRAP_MTOR_ST	P19484	TFEB	P42345	MTOR	S462	S463R	463	Missense	proximal	1	no	10.081	8.771	EPSD	ICGC	6.822	Down-regulation
Atypical_PIKK_FRAP_MTOR_ST	P19484	TFEB	P42345	MTOR	S462	R464P	464	Missense	proximal	2	no	10.081	12.288	EPSD	ICGC;COSMIC	6.822	Up-regulation
Atypical_PIKK_FRAP_MTOR_ST	P19484	TFEB	P42345	MTOR	S462	R465L	465	Missense	distal	3	no	10.081	8.092	EPSD	ICGC;COSMIC	6.822	Down-regulation
Atypical_PIKK_FRAP_MTOR_ST	P19484	TFEB	P42345	MTOR	S463	R464P	464	Missense	proximal	1	no	5.699	15.532	EPSD	ICGC;COSMIC	6.822	Gain
Atypical_PIKK_FRAP_MTOR_ST	P19484	TFEB	P42345	MTOR	S463	R465L	465	Missense	proximal	2	no	5.699	7.216	EPSD	ICGC;COSMIC	6.822	Gain
Atypical_PIKK_FRAP_MTOR_ST	P19484	TFEB	P42345	MTOR	S467	R464H	464	Missense	distal	-3	no	10.630	9.883	EPSD	ICGC;COSMIC	6.822	Down-regulation
Atypical_PIKK_FRAP_MTOR_ST	P19484	TFEB	P42345	MTOR	S467	S463R	463	Missense	distal	-4	no	10.630	10.745	EPSD	ICGC	6.822	Up-regulation
Atypical_PIKK_FRAP_MTOR_ST	P19484	TFEB	P42345	MTOR	S467	E472D	472	Missense	distal	5	no	10.630	11.049	EPSD	ICGC;COSMIC	6.822	Up-regulation
Atypical_PIKK_FRAP_MTOR_ST	P19484	TFEB	P42345	MTOR	S467	R464P	464	Missense	distal	-3	no	10.630	9.852	EPSD	ICGC;COSMIC	6.822	Down-regulation
Atypical_PIKK_FRAP_MTOR_ST	P19484	TFEB	P42345	MTOR	S467	R465L	465	Missense	proximal	-2	no	10.630	10.624	EPSD	ICGC;COSMIC	6.822	Down-regulation
Atypical_PIKK_FRAP_MTOR_ST	P19484	TFEB	P42345	MTOR	S469	R464H	464	Missense	distal	-5	no	17.972	17.976	EPSD	ICGC;COSMIC	6.822	Up-regulation
Atypical_PIKK_FRAP_MTOR_ST	P19484	TFEB	P42345	MTOR	S469	S463R	463	Missense	distal	-6	no	17.972	18.079	EPSD	ICGC	6.822	Up-regulation
Atypical_PIKK_FRAP_MTOR_ST	P19484	TFEB	P42345	MTOR	S469	E472D	472	Missense	distal	3	no	17.972	17.046	EPSD	ICGC;COSMIC	6.822	Down-regulation
Atypical_PIKK_FRAP_MTOR_ST	P19484	TFEB	P42345	MTOR	S469	R464P	464	Missense	distal	-5	no	17.972	17.878	EPSD	ICGC;COSMIC	6.822	Down-regulation
Atypical_PIKK_FRAP_MTOR_ST	P19484	TFEB	P42345	MTOR	S469	R465L	465	Missense	distal	-4	no	17.972	17.542	EPSD	ICGC;COSMIC	6.822	Down-regulation
Atypical_PIKK_FRAP_MTOR_ST	Q9H4L4	SENP3	P42345	MTOR	S26	R29L	29	Missense	distal	3	no	9.652	7.663	PhosphoSitePlus;EPSD	ICGC;COSMIC	6.822	Down-regulation
Atypical_PIKK_FRAP_MTOR_ST	Q9H4L4	SENP3	P42345	MTOR	S169	S169L	169	Missense	central	0	yes	8.666	0.000	EPSD	ICGC;COSMIC	6.822	Loss
Atypical_PIKK_FRAP_MTOR_ST	Q9H4L4	SENP3	P42345	MTOR	T176	S169L	169	Missense	distal	-7	no	7.876	7.307	EPSD	ICGC;COSMIC	6.822	Down-regulation
Atypical_PIKK_FRAP_MTOR_ST	Q9H4L4	SENP3	P42345	MTOR	T176	S181P	181	Missense	distal	5	no	7.876	7.990	EPSD	ICGC	6.822	Up-regulation
Atypical_PIKK_FRAP_MTOR_ST	Q9H4L4	SENP3	P42345	MTOR	S181	R185L	185	Missense	distal	4	no	9.505	9.438	EPSD	ICGC	6.822	Down-regulation
Atypical_PIKK_FRAP_MTOR_ST	Q9H4L4	SENP3	P42345	MTOR	S181	D187Y	187	Missense	distal	6	no	9.505	8.356	EPSD	ICGC	6.822	Down-regulation
Atypical_PIKK_FRAP_MTOR_ST	Q9H4L4	SENP3	P42345	MTOR	S181	S188P	188	Missense	distal	7	no	9.505	9.526	EPSD	ICGC;COSMIC	6.822	Up-regulation
Atypical_PIKK_FRAP_MTOR_ST	Q9H4L4	SENP3	P42345	MTOR	S181	S181P	181	Missense	central	0	yes	9.505	0.000	EPSD	ICGC	6.822	Loss
Atypical_PIKK_FRAP_MTOR_ST	Q9H4L4	SENP3	P42345	MTOR	S188	R185L	185	Missense	distal	-3	no	11.827	11.897	EPSD	ICGC	6.822	Up-regulation
Atypical_PIKK_FRAP_MTOR_ST	Q9H4L4	SENP3	P42345	MTOR	S188	D187Y	187	Missense	proximal	-1	no	11.827	11.716	EPSD	ICGC	6.822	Down-regulation
Atypical_PIKK_FRAP_MTOR_ST	Q9H4L4	SENP3	P42345	MTOR	S188	S188P	188	Missense	central	0	yes	11.827	0.000	EPSD	ICGC;COSMIC	6.822	Loss
Atypical_PIKK_FRAP_MTOR_ST	Q9H4L4	SENP3	P42345	MTOR	S188	S181P	181	Missense	distal	-7	no	11.827	11.390	EPSD	ICGC	6.822	Down-regulation
Atypical_PIKK_FRAP_MTOR_ST	Q9H4L4	SENP3	P42345	MTOR	S212	S217F	217	Missense	distal	5	no	7.513	8.099	EPSD	ICGC	6.822	Up-regulation
Atypical_PIKK_FRAP_MTOR_ST	Q9H4L4	SENP3	P42345	MTOR	T229	R227M	227	Missense	proximal	-2	no	9.516	9.120	EPSD	ICGC;COSMIC	6.822	Down-regulation
Atypical_PIKK_FRAP_MTOR_ST	Q9H4L4	SENP3	P42345	MTOR	S232	D237N	237	Missense	distal	5	no	11.290	12.736	EPSD	ICGC;COSMIC	6.822	Up-regulation
Atypical_PIKK_FRAP_MTOR_ST	Q9H4L4	SENP3	P42345	MTOR	S232	R227M	227	Missense	distal	-5	no	11.290	11.142	EPSD	ICGC;COSMIC	6.822	Down-regulation
Atypical_PIKK_FRAP_MTOR_ST	Q8IYB3	SRRM1	P42345	MTOR	S171	R166G	166	Missense	distal	-5	no	9.699	9.624	EPSD	ICGC;COSMIC	6.822	Down-regulation
Atypical_PIKK_FRAP_MTOR_ST	Q8IYB3	SRRM1	P42345	MTOR	S171	S169C	169	Missense	proximal	-2	no	9.699	9.848	EPSD	ICGC	6.822	Up-regulation
Atypical_PIKK_FRAP_MTOR_ST	Q8IYB3	SRRM1	P42345	MTOR	S171	R170L	170	Missense	proximal	-1	no	9.699	9.659	EPSD	ICGC	6.822	Down-regulation
Atypical_PIKK_FRAP_MTOR_ST	Q8IYB3	SRRM1	P42345	MTOR	S179	P180Q	180	Missense	proximal	1	no	12.220	3.606	EPSD	ICGC	6.822	Loss
Atypical_PIKK_FRAP_MTOR_ST	Q8IYB3	SRRM1	P42345	MTOR	S179	P180L	180	Missense	proximal	1	no	12.220	6.251	EPSD	ICGC	6.822	Loss
Atypical_PIKK_FRAP_MTOR_ST	Q8IYB3	SRRM1	P42345	MTOR	S181	P180Q	180	Missense	proximal	-1	no	7.856	7.782	EPSD	ICGC	6.822	Down-regulation
Atypical_PIKK_FRAP_MTOR_ST	Q8IYB3	SRRM1	P42345	MTOR	S181	P180L	180	Missense	proximal	-1	no	7.856	7.723	EPSD	ICGC	6.822	Down-regulation
Atypical_PIKK_FRAP_MTOR_ST	Q8IYB3	SRRM1	P42345	MTOR	S181	P188H	188	Missense	distal	7	no	7.856	8.471	EPSD	ICGC;COSMIC	6.822	Up-regulation
Atypical_PIKK_FRAP_MTOR_ST	Q8IYB3	SRRM1	P42345	MTOR	S187	R193I	193	Missense	distal	6	no	8.969	9.928	EPSD	ICGC	6.822	Up-regulation
Atypical_PIKK_FRAP_MTOR_ST	Q8IYB3	SRRM1	P42345	MTOR	S187	P180Q	180	Missense	distal	-7	no	8.969	8.570	EPSD	ICGC	6.822	Down-regulation
Atypical_PIKK_FRAP_MTOR_ST	Q8IYB3	SRRM1	P42345	MTOR	S187	P180L	180	Missense	distal	-7	no	8.969	8.837	EPSD	ICGC	6.822	Down-regulation
Atypical_PIKK_FRAP_MTOR_ST	Q8IYB3	SRRM1	P42345	MTOR	S187	P188H	188	Missense	proximal	1	no	8.969	-18.222	EPSD	ICGC;COSMIC	6.822	Loss
Atypical_PIKK_FRAP_MTOR_ST	Q8IYB3	SRRM1	P42345	MTOR	S187	R191I	191	Missense	distal	4	no	8.969	9.106	EPSD	ICGC;COSMIC	6.822	Up-regulation
Atypical_PIKK_FRAP_MTOR_ST	Q8IYB3	SRRM1	P42345	MTOR	S292	R291C	291	Missense	proximal	-1	no	10.554	10.727	EPSD	ICGC	6.822	Up-regulation
Atypical_PIKK_FRAP_MTOR_ST	Q8IYB3	SRRM1	P42345	MTOR	S292	T288M	288	Missense	distal	-4	no	10.554	10.329	EPSD	ICGC;COSMIC	6.822	Down-regulation
Atypical_PIKK_FRAP_MTOR_ST	Q8IYB3	SRRM1	P42345	MTOR	S292	R291S	291	Missense	proximal	-1	no	10.554	10.716	EPSD	ICGC;COSMIC	6.822	Up-regulation
Atypical_PIKK_FRAP_MTOR_ST	Q8IYB3	SRRM1	P42345	MTOR	S310	R305L	305	Missense	distal	-5	no	9.567	9.401	EPSD	ICGC;COSMIC	6.822	Down-regulation
Atypical_PIKK_FRAP_MTOR_ST	Q8IYB3	SRRM1	P42345	MTOR	S310	P317Q	317	Missense	distal	7	no	9.567	9.939	EPSD	ICGC;COSMIC	6.822	Up-regulation
Atypical_PIKK_FRAP_MTOR_ST	Q8IYB3	SRRM1	P42345	MTOR	S316	P323S	323	Missense	distal	7	no	15.324	15.303	EPSD	ICGC	6.822	Down-regulation
Atypical_PIKK_FRAP_MTOR_ST	Q8IYB3	SRRM1	P42345	MTOR	S316	P323F	323	Missense	distal	7	no	15.324	15.883	EPSD	ICGC	6.822	Up-regulation
Atypical_PIKK_FRAP_MTOR_ST	Q8IYB3	SRRM1	P42345	MTOR	S316	P317Q	317	Missense	proximal	1	no	15.324	6.710	EPSD	ICGC;COSMIC	6.822	Loss
Atypical_PIKK_FRAP_MTOR_ST	Q8IYB3	SRRM1	P42345	MTOR	S316	R320Q	320	Missense	distal	4	no	15.324	15.455	EPSD	ICGC;COSMIC	6.822	Up-regulation
Atypical_PIKK_FRAP_MTOR_ST	Q8IYB3	SRRM1	P42345	MTOR	S322	P323S	323	Missense	proximal	1	no	9.409	0.886	EPSD	ICGC	6.822	Loss
Atypical_PIKK_FRAP_MTOR_ST	Q8IYB3	SRRM1	P42345	MTOR	S322	P323F	323	Missense	proximal	1	no	9.409	2.889	EPSD	ICGC	6.822	Loss
Atypical_PIKK_FRAP_MTOR_ST	Q8IYB3	SRRM1	P42345	MTOR	S322	P328A	328	Missense	distal	6	no	9.409	8.789	EPSD	ICGC;COSMIC	6.822	Down-regulation
Atypical_PIKK_FRAP_MTOR_ST	Q8IYB3	SRRM1	P42345	MTOR	S322	P317Q	317	Missense	distal	-5	no	9.409	9.418	EPSD	ICGC;COSMIC	6.822	Up-regulation
Atypical_PIKK_FRAP_MTOR_ST	Q8IYB3	SRRM1	P42345	MTOR	S322	R320Q	320	Missense	proximal	-2	no	9.409	9.749	EPSD	ICGC;COSMIC	6.822	Up-regulation
Atypical_PIKK_FRAP_MTOR_ST	Q8IYB3	SRRM1	P42345	MTOR	T327	M332I	332	Missense	distal	5	no	6.931	7.567	EPSD	ICGC	6.822	Up-regulation
Atypical_PIKK_FRAP_MTOR_ST	Q8IYB3	SRRM1	P42345	MTOR	T327	P323S	323	Missense	distal	-4	no	6.931	7.060	EPSD	ICGC	6.822	Up-regulation
Atypical_PIKK_FRAP_MTOR_ST	Q8IYB3	SRRM1	P42345	MTOR	T327	P323F	323	Missense	distal	-4	no	6.931	7.084	EPSD	ICGC	6.822	Up-regulation
Atypical_PIKK_FRAP_MTOR_ST	Q8IYB3	SRRM1	P42345	MTOR	T327	P328A	328	Missense	proximal	1	no	6.931	-1.952	EPSD	ICGC;COSMIC	6.822	Loss
Atypical_PIKK_FRAP_MTOR_ST	Q8IYB3	SRRM1	P42345	MTOR	T327	R320Q	320	Missense	distal	-7	no	6.931	6.853	EPSD	ICGC;COSMIC	6.822	Down-regulation
Atypical_PIKK_FRAP_MTOR_ST	Q8IYB3	SRRM1	P42345	MTOR	S369	S365Y	365	Missense	distal	-4	no	10.532	9.901	EPSD	ICGC;COSMIC	6.822	Down-regulation
Atypical_PIKK_FRAP_MTOR_ST	Q8IYB3	SRRM1	P42345	MTOR	S369	P370L	370	Missense	proximal	1	no	10.532	4.563	EPSD	ICGC;COSMIC	6.822	Loss
Atypical_PIKK_FRAP_MTOR_ST	Q8IYB3	SRRM1	P42345	MTOR	S402	P407S	407	Missense	distal	5	no	13.734	13.621	EPSD	ICGC	6.822	Down-regulation
Atypical_PIKK_FRAP_MTOR_ST	Q8IYB3	SRRM1	P42345	MTOR	S414	P407S	407	Missense	distal	-7	no	14.162	14.599	EPSD	ICGC	6.822	Up-regulation
Atypical_PIKK_FRAP_MTOR_ST	Q8IYB3	SRRM1	P42345	MTOR	S524	R522W	522	Missense	proximal	-2	no	11.164	10.865	EPSD	ICGC	6.822	Down-regulation
Atypical_PIKK_FRAP_MTOR_ST	Q8IYB3	SRRM1	P42345	MTOR	S541	P542A	542	Missense	proximal	1	no	7.464	-1.419	EPSD	ICGC;COSMIC	6.822	Loss
Atypical_PIKK_FRAP_MTOR_ST	Q8IYB3	SRRM1	P42345	MTOR	S541	S541C	541	Missense	central	0	yes	7.464	0.000	EPSD	ICGC;COSMIC	6.822	Loss
Atypical_PIKK_FRAP_MTOR_ST	Q8IYB3	SRRM1	P42345	MTOR	S549	P552Q	552	Missense	distal	3	no	13.097	11.565	EPSD	ICGC;COSMIC	6.822	Down-regulation
Atypical_PIKK_FRAP_MTOR_ST	Q8IYB3	SRRM1	P42345	MTOR	S549	P542A	542	Missense	distal	-7	no	13.097	12.694	EPSD	ICGC;COSMIC	6.822	Down-regulation
Atypical_PIKK_FRAP_MTOR_ST	Q8IYB3	SRRM1	P42345	MTOR	S549	R556S	556	Missense	distal	7	no	13.097	12.304	EPSD	ICGC;COSMIC	6.822	Down-regulation
Atypical_PIKK_FRAP_MTOR_ST	Q8IYB3	SRRM1	P42345	MTOR	S551	P552Q	552	Missense	proximal	1	no	8.444	-0.170	EPSD	ICGC;COSMIC	6.822	Loss
Atypical_PIKK_FRAP_MTOR_ST	Q8IYB3	SRRM1	P42345	MTOR	S551	R556S	556	Missense	distal	5	no	8.444	7.452	EPSD	ICGC;COSMIC	6.822	Down-regulation
Atypical_PIKK_FRAP_MTOR_ST	Q8IYB3	SRRM1	P42345	MTOR	S560	S560F	560	Missense	central	0	yes	9.545	0.000	EPSD	ICGC;COSMIC	6.822	Loss
Atypical_PIKK_FRAP_MTOR_ST	Q8IYB3	SRRM1	P42345	MTOR	S560	R559W	559	Missense	proximal	-1	no	9.545	9.617	EPSD	ICGC;COSMIC	6.822	Up-regulation
Atypical_PIKK_FRAP_MTOR_ST	Q8IYB3	SRRM1	P42345	MTOR	S560	R556S	556	Missense	distal	-4	no	9.545	9.430	EPSD	ICGC;COSMIC	6.822	Down-regulation
Atypical_PIKK_FRAP_MTOR_ST	Q8IYB3	SRRM1	P42345	MTOR	S562	S560F	560	Missense	proximal	-2	no	7.199	7.377	EPSD	ICGC;COSMIC	6.822	Up-regulation
Atypical_PIKK_FRAP_MTOR_ST	Q8IYB3	SRRM1	P42345	MTOR	S562	R559W	559	Missense	distal	-3	no	7.199	6.983	EPSD	ICGC;COSMIC	6.822	Down-regulation
Atypical_PIKK_FRAP_MTOR_ST	Q8IYB3	SRRM1	P42345	MTOR	S562	R556S	556	Missense	distal	-6	no	7.199	7.092	EPSD	ICGC;COSMIC	6.822	Down-regulation
Atypical_PIKK_FRAP_MTOR_ST	Q8IYB3	SRRM1	P42345	MTOR	T572	R579Q	579	Missense	distal	7	no	7.638	7.238	EPSD;PhosphoSitePlus	ICGC;COSMIC;CCLE	6.822	Down-regulation
Atypical_PIKK_FRAP_MTOR_ST	Q8IYB3	SRRM1	P42345	MTOR	T572	R571M	571	Missense	proximal	-1	no	7.638	7.696	EPSD;PhosphoSitePlus	ICGC;COSMIC	6.822	Up-regulation
Atypical_PIKK_FRAP_MTOR_ST	Q8IYB3	SRRM1	P42345	MTOR	T572	R579L	579	Missense	distal	7	no	7.638	7.822	EPSD;PhosphoSitePlus	ICGC;COSMIC	6.822	Up-regulation
Atypical_PIKK_FRAP_MTOR_ST	Q8IYB3	SRRM1	P42345	MTOR	T572	P575S	575	Missense	distal	3	no	7.638	7.652	EPSD;PhosphoSitePlus	ICGC;COSMIC	6.822	Up-regulation
Atypical_PIKK_FRAP_MTOR_ST	Q8IYB3	SRRM1	P42345	MTOR	T572	P575H	575	Missense	distal	3	no	7.638	7.542	EPSD;PhosphoSitePlus	ICGC;COSMIC	6.822	Down-regulation
Atypical_PIKK_FRAP_MTOR_ST	Q8IYB3	SRRM1	P42345	MTOR	T572	P576S	576	Missense	distal	4	no	7.638	7.894	EPSD;PhosphoSitePlus	ICGC;COSMIC	6.822	Up-regulation
Atypical_PIKK_FRAP_MTOR_ST	Q8IYB3	SRRM1	P42345	MTOR	T574	R579Q	579	Missense	distal	5	no	9.794	8.987	PhosphoSitePlus;EPSD	ICGC;COSMIC;CCLE	6.822	Down-regulation
Atypical_PIKK_FRAP_MTOR_ST	Q8IYB3	SRRM1	P42345	MTOR	T574	R571M	571	Missense	distal	-3	no	9.794	8.595	PhosphoSitePlus;EPSD	ICGC;COSMIC	6.822	Down-regulation
Atypical_PIKK_FRAP_MTOR_ST	Q8IYB3	SRRM1	P42345	MTOR	T574	R579L	579	Missense	distal	5	no	9.794	10.288	PhosphoSitePlus;EPSD	ICGC;COSMIC	6.822	Up-regulation
Atypical_PIKK_FRAP_MTOR_ST	Q8IYB3	SRRM1	P42345	MTOR	T574	P575S	575	Missense	proximal	1	no	9.794	1.270	PhosphoSitePlus;EPSD	ICGC;COSMIC	6.822	Loss
Atypical_PIKK_FRAP_MTOR_ST	Q8IYB3	SRRM1	P42345	MTOR	T574	P575H	575	Missense	proximal	1	no	9.794	-17.397	PhosphoSitePlus;EPSD	ICGC;COSMIC	6.822	Loss
Atypical_PIKK_FRAP_MTOR_ST	Q8IYB3	SRRM1	P42345	MTOR	T574	P576S	576	Missense	proximal	2	no	9.794	9.299	PhosphoSitePlus;EPSD	ICGC;COSMIC	6.822	Down-regulation
Atypical_PIKK_FRAP_MTOR_ST	Q8IYB3	SRRM1	P42345	MTOR	T581	R579Q	579	Missense	proximal	-2	no	8.125	8.465	EPSD	ICGC;COSMIC;CCLE	6.822	Up-regulation
Atypical_PIKK_FRAP_MTOR_ST	Q8IYB3	SRRM1	P42345	MTOR	T581	R579L	579	Missense	proximal	-2	no	8.125	8.118	EPSD	ICGC;COSMIC	6.822	Down-regulation
Atypical_PIKK_FRAP_MTOR_ST	Q8IYB3	SRRM1	P42345	MTOR	T581	P575S	575	Missense	distal	-6	no	8.125	8.105	EPSD	ICGC;COSMIC	6.822	Down-regulation
Atypical_PIKK_FRAP_MTOR_ST	Q8IYB3	SRRM1	P42345	MTOR	T581	P575H	575	Missense	distal	-6	no	8.125	7.405	EPSD	ICGC;COSMIC	6.822	Down-regulation
Atypical_PIKK_FRAP_MTOR_ST	Q8IYB3	SRRM1	P42345	MTOR	T581	P576S	576	Missense	distal	-5	no	8.125	8.077	EPSD	ICGC;COSMIC	6.822	Down-regulation
Atypical_PIKK_FRAP_MTOR_ST	Q8IYB3	SRRM1	P42345	MTOR	T581	R587Q	587	Missense	distal	6	no	8.125	8.509	EPSD	ICGC	6.822	Up-regulation
Atypical_PIKK_FRAP_MTOR_ST	Q8IYB3	SRRM1	P42345	MTOR	S583	R579Q	579	Missense	distal	-4	no	12.711	12.214	EPSD	ICGC;COSMIC;CCLE	6.822	Down-regulation
Atypical_PIKK_FRAP_MTOR_ST	Q8IYB3	SRRM1	P42345	MTOR	S583	R579L	579	Missense	distal	-4	no	12.711	12.281	EPSD	ICGC;COSMIC	6.822	Down-regulation
Atypical_PIKK_FRAP_MTOR_ST	Q8IYB3	SRRM1	P42345	MTOR	S583	P576S	576	Missense	distal	-7	no	12.711	13.148	EPSD	ICGC;COSMIC	6.822	Up-regulation
Atypical_PIKK_FRAP_MTOR_ST	Q8IYB3	SRRM1	P42345	MTOR	S583	R587Q	587	Missense	distal	4	no	12.711	12.843	EPSD	ICGC	6.822	Up-regulation
Atypical_PIKK_FRAP_MTOR_ST	Q8IYB3	SRRM1	P42345	MTOR	S590	R587Q	587	Missense	distal	-3	no	12.644	12.036	EPSD	ICGC	6.822	Down-regulation
Atypical_PIKK_FRAP_MTOR_ST	Q8IYB3	SRRM1	P42345	MTOR	S592	R587Q	587	Missense	distal	-5	no	8.159	8.074	EPSD	ICGC	6.822	Down-regulation
Atypical_PIKK_FRAP_MTOR_ST	Q8IYB3	SRRM1	P42345	MTOR	S616	S616F	616	Missense	central	0	yes	12.806	0.000	EPSD	ICGC	6.822	Loss
Atypical_PIKK_FRAP_MTOR_ST	Q8IYB3	SRRM1	P42345	MTOR	S626	P629H	629	Missense	distal	3	no	7.806	7.711	EPSD	ICGC	6.822	Down-regulation
Atypical_PIKK_FRAP_MTOR_ST	Q8IYB3	SRRM1	P42345	MTOR	S628	P629H	629	Missense	proximal	1	no	9.864	-17.327	EPSD	ICGC	6.822	Loss
Atypical_PIKK_FRAP_MTOR_ST	Q8IYB3	SRRM1	P42345	MTOR	S713	R719I	719	Missense	distal	6	no	9.994	10.953	EPSD	ICGC;COSMIC	6.822	Up-regulation
Atypical_PIKK_FRAP_MTOR_ST	Q8IYB3	SRRM1	P42345	MTOR	S715	R719I	719	Missense	distal	4	no	11.835	11.972	EPSD	ICGC;COSMIC	6.822	Up-regulation
Atypical_PIKK_FRAP_MTOR_ST	Q8IYB3	SRRM1	P42345	MTOR	T727	T727A	727	Missense	central	0	yes	10.270	0.000	EPSD	ICGC;COSMIC	6.822	Loss
Atypical_PIKK_FRAP_MTOR_ST	Q8IYB3	SRRM1	P42345	MTOR	S756	S749N	749	Missense	distal	-7	no	10.971	10.781	EPSD	ICGC;COSMIC	6.822	Down-regulation
Atypical_PIKK_FRAP_MTOR_ST	Q8IYB3	SRRM1	P42345	MTOR	S756	S749Y	749	Missense	distal	-7	no	10.971	10.883	EPSD	ICGC;COSMIC	6.822	Down-regulation
Atypical_PIKK_FRAP_MTOR_ST	Q8IYB3	SRRM1	P42345	MTOR	S791	P794L	794	Missense	distal	3	no	9.063	6.808	EPSD	ICGC;COSMIC	6.822	Loss
Atypical_PIKK_FRAP_MTOR_ST	Q8IYB3	SRRM1	P42345	MTOR	S795	P794L	794	Missense	proximal	-1	no	11.414	11.280	EPSD	ICGC;COSMIC	6.822	Down-regulation
Atypical_PIKK_FRAP_MTOR_ST	Q8IYB3	SRRM1	P42345	MTOR	S797	P794L	794	Missense	distal	-3	no	16.250	17.097	EPSD	ICGC;COSMIC	6.822	Up-regulation
Atypical_PIKK_FRAP_MTOR_ST	Q8IYB3	SRRM1	P42345	MTOR	S894	A891V	891	Missense	distal	-3	no	6.327	6.957	EPSD	ICGC;COSMIC	6.822	Gain
Atypical_PIKK_FRAP_MTOR_ST	P51397	DAP	P42345	MTOR	S51	P50H	50	Missense	proximal	-1	no	7.608	7.556	PhosphoSitePlus	ICGC;COSMIC	6.822	Down-regulation
Atypical_PIKK_FRAP_MTOR_ST	P51397	DAP	P42345	MTOR	S51	S51G	51	Missense	central	0	yes	7.608	0.000	PhosphoSitePlus	ICGC;COSMIC	6.822	Loss
Atypical_PIKK_FRAP_MTOR_ST	P51397	DAP	P42345	MTOR	S91	S85N	85	Missense	distal	-6	no	15.928	15.241	EPSD	ICGC	6.822	Down-regulation
Atypical_PIKK_FRAP_MTOR_ST	O95817	BAG3	P42345	MTOR	S134	M141I	141	Missense	distal	7	no	6.773	7.008	EPSD	ICGC;COSMIC	6.822	Gain
Atypical_PIKK_FRAP_MTOR_ST	O95817	BAG3	P42345	MTOR	S136	R139W	139	Missense	distal	3	no	7.958	6.198	EPSD	ICGC;COSMIC	6.822	Loss
Atypical_PIKK_FRAP_MTOR_ST	O95817	BAG3	P42345	MTOR	S136	R139Q	139	Missense	distal	3	no	7.958	6.692	EPSD	ICGC;COSMIC	6.822	Loss
Atypical_PIKK_FRAP_MTOR_ST	O95817	BAG3	P42345	MTOR	S136	M141I	141	Missense	distal	5	no	7.958	8.594	EPSD	ICGC;COSMIC	6.822	Up-regulation
Atypical_PIKK_FRAP_MTOR_ST	O95817	BAG3	P42345	MTOR	S136	E143V	143	Missense	distal	7	no	7.958	8.921	EPSD	ICGC;COSMIC	6.822	Up-regulation
Atypical_PIKK_FRAP_MTOR_ST	O95817	BAG3	P42345	MTOR	S136	S134F	134	Missense	proximal	-2	no	7.958	8.136	EPSD	ICGC;COSMIC	6.822	Up-regulation
Atypical_PIKK_FRAP_MTOR_ST	O95817	BAG3	P42345	MTOR	S173	P174Q	174	Missense	proximal	1	no	9.376	0.762	EPSD	ICGC;COSMIC	6.822	Loss
Atypical_PIKK_FRAP_MTOR_ST	O95817	BAG3	P42345	MTOR	S181	P174Q	174	Missense	distal	-7	no	8.827	8.428	EPSD	ICGC;COSMIC	6.822	Down-regulation
Atypical_PIKK_FRAP_MTOR_ST	O95817	BAG3	P42345	MTOR	S181	S185L	185	Missense	distal	4	no	8.827	8.187	EPSD	ICGC;COSMIC;GDSC	6.822	Down-regulation
Atypical_PIKK_FRAP_MTOR_ST	O95817	BAG3	P42345	MTOR	S187	G192V	192	Missense	distal	5	no	6.672	7.132	EPSD	ICGC	6.822	Gain
Atypical_PIKK_FRAP_MTOR_ST	O95817	BAG3	P42345	MTOR	S207	P202L	202	Missense	distal	-5	no	7.046	6.975	EPSD	ICGC;COSMIC	6.822	Down-regulation
Atypical_PIKK_FRAP_MTOR_ST	O95817	BAG3	P42345	MTOR	S207	Y205H	205	Missense	proximal	-2	no	7.046	7.231	EPSD	ICGC;GDSC;CCLE	6.822	Up-regulation
Atypical_PIKK_FRAP_MTOR_ST	O95817	BAG3	P42345	MTOR	S207	P202Q	202	Missense	distal	-5	no	7.046	7.055	EPSD	ICGC;COSMIC	6.822	Up-regulation
Atypical_PIKK_FRAP_MTOR_ST	O95817	BAG3	P42345	MTOR	S264	A262V	262	Missense	proximal	-2	no	10.328	9.849	EPSD	ICGC	6.822	Down-regulation
Atypical_PIKK_FRAP_MTOR_ST	O95817	BAG3	P42345	MTOR	S264	R261L	261	Missense	distal	-3	no	10.328	10.397	EPSD	ICGC	6.822	Up-regulation
Atypical_PIKK_FRAP_MTOR_ST	O95817	BAG3	P42345	MTOR	S269	A262V	262	Missense	distal	-7	no	7.798	7.910	EPSD	ICGC	6.822	Up-regulation
Atypical_PIKK_FRAP_MTOR_ST	O95817	BAG3	P42345	MTOR	S269	S274L	274	Missense	distal	5	no	7.798	9.285	EPSD	ICGC	6.822	Up-regulation
Atypical_PIKK_FRAP_MTOR_ST	O95817	BAG3	P42345	MTOR	S279	S274L	274	Missense	distal	-5	no	12.887	12.863	EPSD	ICGC	6.822	Down-regulation
Atypical_PIKK_FRAP_MTOR_ST	O95817	BAG3	P42345	MTOR	S279	T285M	285	Missense	distal	6	no	12.887	12.417	EPSD	ICGC;COSMIC	6.822	Down-regulation
Atypical_PIKK_FRAP_MTOR_ST	O95817	BAG3	P42345	MTOR	T285	T285M	285	Missense	central	0	yes	8.855	0.000	PhosphoSitePlus;EPSD	ICGC;COSMIC	6.822	Loss
Atypical_PIKK_FRAP_MTOR_ST	O95817	BAG3	P42345	MTOR	S289	R294C	294	Missense	distal	5	no	14.805	14.590	EPSD;PhosphoSitePlus	ICGC;COSMIC	6.822	Down-regulation
Atypical_PIKK_FRAP_MTOR_ST	O95817	BAG3	P42345	MTOR	S289	T285M	285	Missense	distal	-4	no	14.805	14.580	EPSD;PhosphoSitePlus	ICGC;COSMIC	6.822	Down-regulation
Atypical_PIKK_FRAP_MTOR_ST	O95817	BAG3	P42345	MTOR	S291	R294C	294	Missense	distal	3	no	11.061	8.573	EPSD	ICGC;COSMIC	6.822	Down-regulation
Atypical_PIKK_FRAP_MTOR_ST	O95817	BAG3	P42345	MTOR	S291	V298L	298	Missense	distal	7	no	11.061	11.525	EPSD	ICGC;COSMIC	6.822	Up-regulation
Atypical_PIKK_FRAP_MTOR_ST	O95817	BAG3	P42345	MTOR	S291	T285M	285	Missense	distal	-6	no	11.061	11.131	EPSD	ICGC;COSMIC	6.822	Up-regulation
Atypical_PIKK_FRAP_MTOR_ST	O95817	BAG3	P42345	MTOR	S386	A391S	391	Missense	distal	5	no	10.169	9.741	EPSD	ICGC	6.822	Down-regulation
Atypical_PIKK_FRAP_MTOR_ST	O95817	BAG3	P42345	MTOR	S386	P387L	387	Missense	proximal	1	no	10.169	4.200	EPSD	ICGC;COSMIC	6.822	Loss
Atypical_PIKK_FRAP_MTOR_ST	O95817	BAG3	P42345	MTOR	T406	P407L	407	Missense	proximal	1	no	9.329	3.360	EPSD	ICGC;COSMIC	6.822	Loss
Atypical_PIKK_FRAP_MTOR_ST	O95817	BAG3	P42345	MTOR	T406	P410A	410	Missense	distal	4	no	9.329	9.111	EPSD	ICGC;COSMIC;GDSC;CCLE	6.822	Down-regulation
Atypical_PIKK_FRAP_MTOR_ST	Q9NQG5	RPRD1B	P42345	MTOR	S164	Y161H	161	Missense	distal	-3	no	8.183	7.543	EPSD	ICGC;COSMIC	6.822	Down-regulation
Atypical_PIKK_FRAP_MTOR_ST	Q9NQG5	RPRD1B	P42345	MTOR	S164	E157D	157	Missense	distal	-7	no	8.183	8.833	EPSD	ICGC	6.822	Up-regulation
Atypical_PIKK_FRAP_MTOR_ST	Q9NQG5	RPRD1B	P42345	MTOR	S164	P167S	167	Missense	distal	3	no	8.183	8.197	EPSD	ICGC	6.822	Up-regulation
Atypical_PIKK_FRAP_MTOR_ST	Q9NQG5	RPRD1B	P42345	MTOR	S166	Y161H	161	Missense	distal	-5	no	12.232	11.884	PhosphoSitePlus	ICGC;COSMIC	6.822	Down-regulation
Atypical_PIKK_FRAP_MTOR_ST	Q9NQG5	RPRD1B	P42345	MTOR	S166	P167S	167	Missense	proximal	1	no	12.232	3.708	PhosphoSitePlus	ICGC	6.822	Loss
Atypical_PIKK_FRAP_MTOR_ST	Q9UPY5	SLC7A11	P42345	MTOR	S51	V44I	44	Missense	distal	-7	no	7.824	7.546	EPSD	ICGC;COSMIC	6.822	Down-regulation
Atypical_PIKK_FRAP_MTOR_ST	Q86TB9	PATL1	P42345	MTOR	S184	A189V	189	Missense	distal	5	no	15.841	16.535	EPSD;PhosphoSitePlus	ICGC;COSMIC	6.822	Up-regulation
Atypical_PIKK_FRAP_MTOR_ST	Q86TB9	PATL1	P42345	MTOR	T194	A189V	189	Missense	distal	-5	no	11.270	11.180	EPSD	ICGC;COSMIC	6.822	Down-regulation
Atypical_PIKK_FRAP_MTOR_ST	Q86TB9	PATL1	P42345	MTOR	S233	P234T	234	Missense	proximal	1	no	11.026	4.755	EPSD	ICGC;COSMIC	6.822	Loss
Atypical_PIKK_FRAP_MTOR_ST	Q86TB9	PATL1	P42345	MTOR	S259	P260T	260	Missense	proximal	1	no	10.583	4.312	EPSD	ICGC;COSMIC	6.822	Loss
Atypical_PIKK_FRAP_MTOR_ST	Q86TB9	PATL1	P42345	MTOR	S259	S253G	253	Missense	distal	-6	no	10.583	10.705	EPSD	ICGC;COSMIC	6.822	Up-regulation
Atypical_PIKK_FRAP_MTOR_ST	Q86TB9	PATL1	P42345	MTOR	S259	R263I	263	Missense	distal	4	no	10.583	10.720	EPSD	ICGC;COSMIC	6.822	Up-regulation
Atypical_PIKK_FRAP_MTOR_ST	Q86TB9	PATL1	P42345	MTOR	S278	R276W	276	Missense	proximal	-2	no	10.419	10.120	EPSD	ICGC;COSMIC	6.822	Down-regulation
Atypical_PIKK_FRAP_MTOR_ST	Q86TB9	PATL1	P42345	MTOR	S278	G275R	275	Missense	distal	-3	no	10.419	10.393	EPSD	ICGC	6.822	Down-regulation
Atypical_PIKK_FRAP_MTOR_ST	Q86TB9	PATL1	P42345	MTOR	S291	A295S	295	Missense	distal	4	no	10.900	11.374	EPSD	ICGC;COSMIC	6.822	Up-regulation
Atypical_PIKK_FRAP_MTOR_ST	Q86TB9	PATL1	P42345	MTOR	S291	V289A	289	Missense	proximal	-2	no	10.900	11.379	EPSD	ICGC	6.822	Up-regulation
Atypical_PIKK_FRAP_MTOR_ST	Q86TB9	PATL1	P42345	MTOR	S738	N742K	742	Missense	distal	4	no	11.419	11.622	EPSD	ICGC	6.822	Up-regulation
Atypical_PIKK_FRAP_MTOR_ST	Q13322	GRB10	P42345	MTOR	S150	S150N	150	Missense	central	0	yes	8.664	0.000	EPSD	ICGC;COSMIC	6.822	Loss
Atypical_PIKK_FRAP_MTOR_ST	Q13322	GRB10	P42345	MTOR	S150	S150R	150	Missense	central	0	yes	8.664	0.000	EPSD	ICGC	6.822	Loss
Atypical_PIKK_FRAP_MTOR_ST	Q13322	GRB10	P42345	MTOR	T155	S150N	150	Missense	distal	-5	no	10.158	10.069	EPSD;PhosphoSitePlus	ICGC;COSMIC	6.822	Down-regulation
Atypical_PIKK_FRAP_MTOR_ST	Q13322	GRB10	P42345	MTOR	T155	S150R	150	Missense	distal	-5	no	10.158	10.300	EPSD;PhosphoSitePlus	ICGC	6.822	Up-regulation
Atypical_PIKK_FRAP_MTOR_ST	Q13322	GRB10	P42345	MTOR	S418	S418I	418	Missense	central	0	yes	9.602	0.000	EPSD	ICGC;COSMIC	6.822	Loss
Atypical_PIKK_FRAP_MTOR_ST	Q13322	GRB10	P42345	MTOR	S428	S426I	426	Missense	proximal	-2	no	8.085	7.645	PhosphoSitePlus;EPSD	ICGC;COSMIC	6.822	Down-regulation
Atypical_PIKK_FRAP_MTOR_ST	O00141	SGK1	P42345	MTOR	S74	P79A	79	Missense	distal	5	no	7.397	7.711	EPSD	ICGC;COSMIC	6.822	Up-regulation
Atypical_PIKK_FRAP_MTOR_ST	O00141	SGK1	P42345	MTOR	S74	L68V	68	Missense	distal	-6	no	7.397	7.529	EPSD	ICGC;COSMIC;CCLE	6.822	Up-regulation
Atypical_PIKK_FRAP_MTOR_ST	O00141	SGK1	P42345	MTOR	S74	P75T	75	Missense	proximal	1	no	7.397	1.125	EPSD	ICGC;COSMIC	6.822	Loss
Atypical_PIKK_FRAP_MTOR_ST	O00141	SGK1	P42345	MTOR	S74	A71P	71	Missense	distal	-3	no	7.397	7.458	EPSD	ICGC	6.822	Up-regulation
Atypical_PIKK_FRAP_MTOR_ST	O00141	SGK1	P42345	MTOR	S74	A71V	71	Missense	distal	-3	no	7.397	8.026	EPSD	ICGC;COSMIC	6.822	Up-regulation
Atypical_PIKK_FRAP_MTOR_ST	O00141	SGK1	P42345	MTOR	S74	A71D	71	Missense	distal	-3	no	7.397	8.015	EPSD	ICGC	6.822	Up-regulation
Atypical_PIKK_FRAP_MTOR_ST	O00141	SGK1	P42345	MTOR	S74	P73T	73	Missense	proximal	-1	no	7.397	7.411	EPSD	ICGC	6.822	Up-regulation
Atypical_PIKK_FRAP_MTOR_ST	O00141	SGK1	P42345	MTOR	S74	P76Q	76	Missense	proximal	2	no	7.397	5.178	EPSD	ICGC	6.822	Loss
Atypical_PIKK_FRAP_MTOR_ST	O00141	SGK1	P42345	MTOR	S74	M69V	69	Missense	distal	-5	no	7.397	7.340	EPSD	ICGC;COSMIC	6.822	Down-regulation
Atypical_PIKK_FRAP_MTOR_ST	O00141	SGK1	P42345	MTOR	S74	P73S	73	Missense	proximal	-1	no	7.397	7.465	EPSD	ICGC;COSMIC	6.822	Up-regulation
Atypical_PIKK_FRAP_MTOR_ST	O00141	SGK1	P42345	MTOR	S74	P77S	77	Missense	distal	3	no	7.397	7.411	EPSD	ICGC;COSMIC	6.822	Up-regulation
Atypical_PIKK_FRAP_MTOR_ST	O00141	SGK1	P42345	MTOR	S74	P79L	79	Missense	distal	5	no	7.397	8.770	EPSD	ICGC;CCLE	6.822	Up-regulation
Atypical_PIKK_FRAP_MTOR_ST	O00141	SGK1	P42345	MTOR	S74	E67D	67	Missense	distal	-7	no	7.397	8.046	EPSD	ICGC	6.822	Up-regulation
Atypical_PIKK_FRAP_MTOR_ST	O00141	SGK1	P42345	MTOR	S74	S74Y	74	Missense	central	0	yes	7.397	0.000	EPSD	ICGC	6.822	Loss
Atypical_PIKK_FRAP_MTOR_ST	O00141	SGK1	P42345	MTOR	S74	M69L	69	Missense	distal	-5	no	7.397	7.379	EPSD	ICGC;COSMIC	6.822	Down-regulation
Atypical_PIKK_FRAP_MTOR_ST	O00141	SGK1	P42345	MTOR	S78	P79A	79	Missense	proximal	1	no	9.405	0.521	EPSD	ICGC;COSMIC	6.822	Loss
Atypical_PIKK_FRAP_MTOR_ST	O00141	SGK1	P42345	MTOR	S78	P75T	75	Missense	distal	-3	no	9.405	9.397	EPSD	ICGC;COSMIC	6.822	Down-regulation
Atypical_PIKK_FRAP_MTOR_ST	O00141	SGK1	P42345	MTOR	S78	A71P	71	Missense	distal	-7	no	9.405	9.808	EPSD	ICGC	6.822	Up-regulation
Atypical_PIKK_FRAP_MTOR_ST	O00141	SGK1	P42345	MTOR	S78	A71V	71	Missense	distal	-7	no	9.405	9.516	EPSD	ICGC;COSMIC	6.822	Up-regulation
Atypical_PIKK_FRAP_MTOR_ST	O00141	SGK1	P42345	MTOR	S78	A71D	71	Missense	distal	-7	no	9.405	10.489	EPSD	ICGC	6.822	Up-regulation
Atypical_PIKK_FRAP_MTOR_ST	O00141	SGK1	P42345	MTOR	S78	P73T	73	Missense	distal	-5	no	9.405	9.363	EPSD	ICGC	6.822	Down-regulation
Atypical_PIKK_FRAP_MTOR_ST	O00141	SGK1	P42345	MTOR	S78	P76Q	76	Missense	proximal	-2	no	9.405	9.261	EPSD	ICGC	6.822	Down-regulation
Atypical_PIKK_FRAP_MTOR_ST	O00141	SGK1	P42345	MTOR	S78	P73S	73	Missense	distal	-5	no	9.405	9.357	EPSD	ICGC;COSMIC	6.822	Down-regulation
Atypical_PIKK_FRAP_MTOR_ST	O00141	SGK1	P42345	MTOR	S78	P77S	77	Missense	proximal	-1	no	9.405	9.473	EPSD	ICGC;COSMIC	6.822	Up-regulation
Atypical_PIKK_FRAP_MTOR_ST	O00141	SGK1	P42345	MTOR	S78	P79L	79	Missense	proximal	1	no	9.405	3.436	EPSD	ICGC;CCLE	6.822	Loss
Atypical_PIKK_FRAP_MTOR_ST	O00141	SGK1	P42345	MTOR	S78	S74Y	74	Missense	distal	-4	no	9.405	8.774	EPSD	ICGC	6.822	Down-regulation
Atypical_PIKK_FRAP_MTOR_ST	O00141	SGK1	P42345	MTOR	T260	P266T	266	Missense	distal	6	no	8.700	7.816	EPSD	ICGC	6.822	Down-regulation
Atypical_PIKK_FRAP_MTOR_ST	O00141	SGK1	P42345	MTOR	T260	T254A	254	Missense	distal	-6	no	8.700	8.421	EPSD	ICGC	6.822	Down-regulation
Atypical_PIKK_FRAP_MTOR_ST	O00141	SGK1	P42345	MTOR	S401	D403E	403	Missense	proximal	2	no	11.591	12.572	EPSD	ICGC	6.822	Up-regulation
Atypical_PIKK_FRAP_MTOR_ST	O00141	SGK1	P42345	MTOR	S401	G399D	399	Missense	proximal	-2	no	11.591	10.537	EPSD	ICGC;COSMIC	6.822	Down-regulation
Atypical_PIKK_FRAP_MTOR_ST	O00141	SGK1	P42345	MTOR	S401	K400E	400	Missense	proximal	-1	no	11.591	11.679	EPSD	ICGC;COSMIC	6.822	Up-regulation
Atypical_PIKK_FRAP_MTOR_ST	O00141	SGK1	P42345	MTOR	S422	G420C	420	Missense	proximal	-2	no	10.641	10.061	PhosphoSitePlus	ICGC;COSMIC	6.822	Down-regulation
Atypical_PIKK_FRAP_MTOR_ST	O00141	SGK1	P42345	MTOR	S422	F418L	418	Missense	distal	-4	no	10.641	10.302	PhosphoSitePlus	ICGC	6.822	Down-regulation
Atypical_PIKK_FRAP_MTOR_ST	O00141	SGK1	P42345	MTOR	S422	E416K	416	Missense	distal	-6	no	10.641	10.496	PhosphoSitePlus	ICGC;COSMIC	6.822	Down-regulation
Atypical_PIKK_FRAP_MTOR_ST	O00141	SGK1	P42345	MTOR	S422	A424V	424	Missense	proximal	2	no	10.641	11.389	PhosphoSitePlus	ICGC;COSMIC	6.822	Up-regulation
Atypical_PIKK_FRAP_MTOR_ST	O00141	SGK1	P42345	MTOR	S422	F418C	418	Missense	distal	-4	no	10.641	8.792	PhosphoSitePlus	ICGC;COSMIC	6.822	Down-regulation
Atypical_PIKK_FRAP_MTOR_ST	O96018	APBA3	P42345	MTOR	S9	S9F	9	Missense	central	0	yes	9.984	0.000	EPSD	ICGC;COSMIC	6.822	Loss
Atypical_PIKK_FRAP_MTOR_ST	O96018	APBA3	P42345	MTOR	S9	G12W	12	Missense	distal	3	no	9.984	6.877	EPSD	ICGC;COSMIC	6.822	Down-regulation
Atypical_PIKK_FRAP_MTOR_ST	O96018	APBA3	P42345	MTOR	S372	C376R	376	Missense	distal	4	no	11.258	11.471	EPSD	ICGC;COSMIC	6.822	Up-regulation
Atypical_PIKK_FRAP_MTOR_ST	O96018	APBA3	P42345	MTOR	S372	V369M	369	Missense	distal	-3	no	11.258	10.269	EPSD	ICGC;COSMIC	6.822	Down-regulation
Atypical_PIKK_FRAP_MTOR_ST	P31749	AKT1	P42345	MTOR	T92	H89R	89	Missense	distal	-3	no	7.076	7.823	EPSD	ICGC	6.822	Up-regulation
Atypical_PIKK_FRAP_MTOR_ST	P31749	AKT1	P42345	MTOR	T92	E85K	85	Missense	distal	-7	no	7.076	6.867	EPSD	ICGC;COSMIC	6.822	Down-regulation
Atypical_PIKK_FRAP_MTOR_ST	P31749	AKT1	P42345	MTOR	T92	R96L	96	Missense	distal	4	no	7.076	7.009	EPSD	ICGC;COSMIC	6.822	Down-regulation
Atypical_PIKK_FRAP_MTOR_ST	P31749	AKT1	P42345	MTOR	T312	T305N	305	Missense	distal	-7	no	10.450	10.208	EPSD	ICGC	6.822	Down-regulation
Atypical_PIKK_FRAP_MTOR_ST	P31749	AKT1	P42345	MTOR	S422	K420T	420	Missense	proximal	-2	no	10.195	10.131	EPSD	ICGC	6.822	Down-regulation
Atypical_PIKK_FRAP_MTOR_ST	P31749	AKT1	P42345	MTOR	T450	Q454K	454	Missense	distal	4	no	13.470	13.641	EPSD;PhosphoSitePlus	ICGC	6.822	Up-regulation
Atypical_PIKK_FRAP_MTOR_ST	P31749	AKT1	P42345	MTOR	T450	S457R	457	Missense	distal	7	no	13.470	14.263	EPSD;PhosphoSitePlus	ICGC	6.822	Up-regulation
Atypical_PIKK_FRAP_MTOR_ST	P31749	AKT1	P42345	MTOR	S473	Q471K	471	Missense	proximal	-2	no	13.336	13.253	PhosphoSitePlus;EPSD	ICGC	6.822	Down-regulation
Atypical_PIKK_FRAP_MTOR_ST	P31749	AKT1	P42345	MTOR	S473	S477R	477	Missense	distal	4	no	13.336	12.763	PhosphoSitePlus;EPSD	ICGC	6.822	Down-regulation
Atypical_PIKK_FRAP_MTOR_ST	P31749	AKT1	P42345	MTOR	S477	Q471K	471	Missense	distal	-6	no	8.451	8.378	EPSD	ICGC	6.822	Down-regulation
Atypical_PIKK_FRAP_MTOR_ST	P31749	AKT1	P42345	MTOR	S477	S477R	477	Missense	central	0	yes	8.451	0.000	EPSD	ICGC	6.822	Loss
Atypical_PIKK_FRAP_MTOR_ST	Q96F24	NRBF2	P42345	MTOR	S268	P262L	262	Missense	distal	-6	no	11.864	11.089	EPSD	ICGC;COSMIC	6.822	Down-regulation
Atypical_PIKK_FRAP_MTOR_ST	Q96F24	NRBF2	P42345	MTOR	S268	P262H	262	Missense	distal	-6	no	11.864	11.144	EPSD	ICGC	6.822	Down-regulation
Atypical_PIKK_FRAP_MTOR_ST	Q8NHG8	ZNRF2	P42345	MTOR	S145	P152Q	152	Missense	distal	7	no	9.832	10.204	PhosphoSitePlus	ICGC;COSMIC	6.822	Up-regulation
Atypical_PIKK_FRAP_MTOR_ST	Q8NHG8	ZNRF2	P42345	MTOR	S145	A148V	148	Missense	distal	3	no	9.832	7.821	PhosphoSitePlus	ICGC;COSMIC	6.822	Down-regulation
Atypical_PIKK_FRAP_MTOR_ST	Q8NHG8	ZNRF2	P42345	MTOR	S151	P152Q	152	Missense	proximal	1	no	7.603	-1.011	EPSD	ICGC;COSMIC	6.822	Loss
Atypical_PIKK_FRAP_MTOR_ST	Q8NHG8	ZNRF2	P42345	MTOR	S151	M154I	154	Missense	distal	3	no	7.603	7.771	EPSD	ICGC;COSMIC	6.822	Up-regulation
Atypical_PIKK_FRAP_MTOR_ST	Q8NHG8	ZNRF2	P42345	MTOR	S151	A148V	148	Missense	distal	-3	no	7.603	8.233	EPSD	ICGC;COSMIC	6.822	Up-regulation
Atypical_PIKK_FRAP_MTOR_ST	P62753	RPS6	P42345	MTOR	S236	A229S	229	Missense	distal	-7	no	9.910	10.750	PhosphoSitePlus;EPSD	ICGC;COSMIC	6.822	Up-regulation
Atypical_PIKK_FRAP_MTOR_ST	P62753	RPS6	P42345	MTOR	S236	A229V	229	Missense	distal	-7	no	9.910	10.021	PhosphoSitePlus;EPSD	ICGC;COSMIC;GDSC;CCLE	6.822	Up-regulation
Atypical_PIKK_FRAP_MTOR_ST	Q96B36	AKT1S1	P42345	MTOR	S92	A99V	99	Missense	distal	7	no	6.717	7.656	EPSD	ICGC;COSMIC	6.822	Gain
Atypical_PIKK_FRAP_MTOR_ST	Q96B36	AKT1S1	P42345	MTOR	S92	A99S	99	Missense	distal	7	no	6.717	7.143	EPSD	ICGC;COSMIC	6.822	Gain
Atypical_PIKK_FRAP_MTOR_ST	O95747	OXSR1	P42345	MTOR	S359	S355L	355	Missense	distal	-4	no	7.588	7.273	EPSD	ICGC;COSMIC	6.822	Down-regulation
Atypical_PIKK_FRAP_MTOR_ST	Q9H1K1	ISCU	P42345	MTOR	S51	K57E	57	Missense	distal	6	no	6.240	7.144	EPSD	ICGC	6.822	Gain
Atypical_PIKK_FRAP_MTOR_ST	Q9BRS8	LARP6	P42345	MTOR	S194	L191F	191	Missense	distal	-3	no	8.261	7.917	EPSD	ICGC	6.822	Down-regulation
Atypical_PIKK_FRAP_MTOR_ST	Q9BRS8	LARP6	P42345	MTOR	S228	S229P	229	Missense	proximal	1	no	7.134	15.658	EPSD	ICGC;COSMIC	6.822	Up-regulation
Atypical_PIKK_FRAP_MTOR_ST	Q9BRS8	LARP6	P42345	MTOR	S228	L233F	233	Missense	distal	5	no	7.134	6.234	EPSD	ICGC;COSMIC	6.822	Loss
Atypical_PIKK_FRAP_MTOR_ST	Q9BRS8	LARP6	P42345	MTOR	S228	V226D	226	Missense	proximal	-2	no	7.134	6.728	EPSD	ICGC	6.822	Loss
Atypical_PIKK_FRAP_MTOR_ST	Q9BRS8	LARP6	P42345	MTOR	S228	G225E	225	Missense	distal	-3	no	7.134	6.388	EPSD	ICGC	6.822	Loss
Atypical_PIKK_FRAP_MTOR_ST	Q9BRS8	LARP6	P42345	MTOR	S228	G222W	222	Missense	distal	-6	no	7.134	7.492	EPSD	ICGC;COSMIC	6.822	Up-regulation
Atypical_PIKK_FRAP_MTOR_ST	Q9BRS8	LARP6	P42345	MTOR	S348	G352S	352	Missense	distal	4	no	10.757	11.280	EPSD;PhosphoSitePlus	ICGC	6.822	Up-regulation
Atypical_PIKK_FRAP_MTOR_ST	Q9BRS8	LARP6	P42345	MTOR	S362	P363Q	363	Missense	proximal	1	no	12.747	4.133	EPSD	ICGC;COSMIC	6.822	Loss
Atypical_PIKK_FRAP_MTOR_ST	Q9BRS8	LARP6	P42345	MTOR	S362	A357T	357	Missense	distal	-5	no	12.747	12.727	EPSD	ICGC;COSMIC	6.822	Down-regulation
Atypical_PIKK_FRAP_MTOR_ST	Q9BRS8	LARP6	P42345	MTOR	S372	P377Q	377	Missense	distal	5	no	11.055	11.126	EPSD	ICGC	6.822	Up-regulation
Atypical_PIKK_FRAP_MTOR_ST	Q9BRS8	LARP6	P42345	MTOR	S372	A375D	375	Missense	distal	3	no	11.055	9.326	EPSD	ICGC	6.822	Down-regulation
Atypical_PIKK_FRAP_MTOR_ST	Q9BRS8	LARP6	P42345	MTOR	S376	P377Q	377	Missense	proximal	1	no	8.196	-0.418	EPSD	ICGC	6.822	Loss
Atypical_PIKK_FRAP_MTOR_ST	Q9BRS8	LARP6	P42345	MTOR	S376	A375D	375	Missense	proximal	-1	no	8.196	8.140	EPSD	ICGC	6.822	Down-regulation
Atypical_PIKK_FRAP_MTOR_ST	Q9BRS8	LARP6	P42345	MTOR	S384	P377Q	377	Missense	distal	-7	no	10.186	9.787	EPSD	ICGC	6.822	Down-regulation
Atypical_PIKK_FRAP_MTOR_ST	Q9BRS8	LARP6	P42345	MTOR	S424	G429S	429	Missense	distal	5	no	7.929	7.267	EPSD	ICGC;COSMIC	6.822	Down-regulation
Atypical_PIKK_FRAP_MTOR_ST	Q9BRS8	LARP6	P42345	MTOR	S424	S421Y	421	Missense	distal	-3	no	7.929	8.168	EPSD	ICGC;COSMIC	6.822	Up-regulation
Atypical_PIKK_FRAP_MTOR_ST	Q9BRS8	LARP6	P42345	MTOR	S424	P427L	427	Missense	distal	3	no	7.929	5.675	EPSD	ICGC	6.822	Loss
Atypical_PIKK_FRAP_MTOR_ST	Q9BRS8	LARP6	P42345	MTOR	S424	P427T	427	Missense	distal	3	no	7.929	7.536	EPSD	ICGC	6.822	Down-regulation
Atypical_PIKK_FRAP_MTOR_ST	Q9BRS8	LARP6	P42345	MTOR	S424	P431T	431	Missense	distal	7	no	7.929	6.962	EPSD	ICGC	6.822	Down-regulation
Atypical_PIKK_FRAP_MTOR_ST	Q9BRS8	LARP6	P42345	MTOR	S430	G429S	429	Missense	proximal	-1	no	7.158	7.165	EPSD	ICGC;COSMIC	6.822	Up-regulation
Atypical_PIKK_FRAP_MTOR_ST	Q9BRS8	LARP6	P42345	MTOR	S430	P427L	427	Missense	distal	-3	no	7.158	8.005	EPSD	ICGC	6.822	Up-regulation
Atypical_PIKK_FRAP_MTOR_ST	Q9BRS8	LARP6	P42345	MTOR	S430	P427T	427	Missense	distal	-3	no	7.158	7.151	EPSD	ICGC	6.822	Down-regulation
Atypical_PIKK_FRAP_MTOR_ST	Q9BRS8	LARP6	P42345	MTOR	S430	P431T	431	Missense	proximal	1	no	7.158	0.886	EPSD	ICGC	6.822	Loss
Atypical_PIKK_FRAP_MTOR_ST	Q9BRS8	LARP6	P42345	MTOR	S430	R434W	434	Missense	distal	4	no	7.158	7.320	EPSD	ICGC;COSMIC	6.822	Up-regulation
Atypical_PIKK_FRAP_MTOR_ST	Q9BRS8	LARP6	P42345	MTOR	S430	R437C	437	Missense	distal	7	no	7.158	7.588	EPSD	ICGC;COSMIC	6.822	Up-regulation
Atypical_PIKK_FRAP_MTOR_ST	Q9BRS8	LARP6	P42345	MTOR	S451	P452S	452	Missense	proximal	1	no	8.920	0.396	EPSD	ICGC	6.822	Loss
Atypical_PIKK_FRAP_MTOR_ST	Q9BRS8	LARP6	P42345	MTOR	S451	L454F	454	Missense	distal	3	no	8.920	11.593	EPSD	ICGC;COSMIC	6.822	Up-regulation
Atypical_PIKK_FRAP_MTOR_ST	P26358	DNMT1	P42345	MTOR	S152	A147T	147	Missense	distal	-5	no	8.884	8.864	EPSD	ICGC	6.822	Down-regulation
Atypical_PIKK_FRAP_MTOR_ST	P26358	DNMT1	P42345	MTOR	S154	A147T	147	Missense	distal	-7	no	7.870	8.762	EPSD	ICGC	6.822	Up-regulation
Atypical_PIKK_FRAP_MTOR_ST	P01106	MYC	P42345	MTOR	T78	P72S	72	Missense	distal	-6	no	7.759	7.738	EPSD	ICGC;COSMIC;GDSC	6.822	Down-regulation
Atypical_PIKK_FRAP_MTOR_ST	P01106	MYC	P42345	MTOR	T78	P72A	72	Missense	distal	-6	no	7.759	7.401	EPSD	ICGC;COSMIC	6.822	Down-regulation
Atypical_PIKK_FRAP_MTOR_ST	P01106	MYC	P42345	MTOR	T78	P72L	72	Missense	distal	-6	no	7.759	6.984	EPSD	ICGC;COSMIC	6.822	Down-regulation
Atypical_PIKK_FRAP_MTOR_ST	P01106	MYC	P42345	MTOR	T78	P72T	72	Missense	distal	-6	no	7.759	7.680	EPSD	ICGC;COSMIC;GDSC	6.822	Down-regulation
Atypical_PIKK_FRAP_MTOR_ST	Q9BPZ7	MAPKAP1	P42345	MTOR	S84	R83L	83	Missense	proximal	-1	no	8.791	8.751	EPSD	ICGC;COSMIC	6.822	Down-regulation
Atypical_PIKK_FRAP_MTOR_ST	Q9BPZ7	MAPKAP1	P42345	MTOR	S84	G79V	79	Missense	distal	-5	no	8.791	8.662	EPSD	ICGC;COSMIC	6.822	Down-regulation
Atypical_PIKK_FRAP_MTOR_ST	Q9Y6W6	DUSP10	P42345	MTOR	S224	R227M	227	Missense	distal	3	no	9.530	7.430	EPSD;PhosphoSitePlus	ICGC;COSMIC	6.822	Down-regulation
Atypical_PIKK_FRAP_MTOR_ST	Q9Y6W6	DUSP10	P42345	MTOR	S230	R227M	227	Missense	distal	-3	no	7.943	6.744	PhosphoSitePlus;EPSD	ICGC;COSMIC	6.822	Loss
Atypical_PIKK_FRAP_MTOR_ST	Q8TBX8	PIP4K2C	P42345	MTOR	S324	P318S	318	Missense	distal	-6	no	10.254	10.233	EPSD;PhosphoSitePlus	ICGC	6.822	Down-regulation
Atypical_PIKK_FRAP_MTOR_ST	Q8TBX8	PIP4K2C	P42345	MTOR	S324	E330V	330	Missense	distal	6	no	10.254	10.126	EPSD;PhosphoSitePlus	ICGC;COSMIC	6.822	Down-regulation
Atypical_PIKK_FRAP_MTOR_ST	Q8TBX8	PIP4K2C	P42345	MTOR	S328	E330V	330	Missense	proximal	2	no	10.768	9.914	PhosphoSitePlus;EPSD	ICGC;COSMIC	6.822	Down-regulation
Atypical_PIKK_FRAP_MTOR_ST	Q9C0C7	AMBRA1	P42345	MTOR	S52	D51N	51	Missense	proximal	-1	no	12.532	12.412	PhosphoSitePlus	ICGC	6.822	Down-regulation
Atypical_PIKK_FRAP_MTOR_ST	Q9C0C7	AMBRA1	P42345	MTOR	S52	T56A	56	Missense	distal	4	no	12.532	11.990	PhosphoSitePlus	ICGC;COSMIC	6.822	Down-regulation
Atypical_PIKK_FRAP_MTOR_ST	Q9C0C7	AMBRA1	P42345	MTOR	S269	P272L	272	Missense	distal	3	no	7.706	5.452	EPSD	ICGC;COSMIC	6.822	Loss
Atypical_PIKK_FRAP_MTOR_ST	Q9C0C7	AMBRA1	P42345	MTOR	S269	Q263H	263	Missense	distal	-6	no	7.706	7.164	EPSD	ICGC;COSMIC	6.822	Down-regulation
Atypical_PIKK_FRAP_MTOR_ST	Q9C0C7	AMBRA1	P42345	MTOR	S269	Q263K	263	Missense	distal	-6	no	7.706	7.632	EPSD	ICGC	6.822	Down-regulation
Atypical_PIKK_FRAP_MTOR_ST	Q9C0C7	AMBRA1	P42345	MTOR	S269	V262M	262	Missense	distal	-7	no	7.706	7.847	EPSD	ICGC;CCLE	6.822	Up-regulation
Atypical_PIKK_FRAP_MTOR_ST	Q9C0C7	AMBRA1	P42345	MTOR	S636	S639T	639	Missense	distal	3	no	6.832	6.424	EPSD	ICGC;COSMIC	6.822	Loss
Atypical_PIKK_FRAP_MTOR_ST	Q9C0C7	AMBRA1	P42345	MTOR	S696	S697P	697	Missense	proximal	1	no	4.888	13.412	EPSD	ICGC;COSMIC	6.822	Gain
Atypical_PIKK_FRAP_MTOR_ST	Q00613	HSF1	P42345	MTOR	S244	P239L	239	Missense	distal	-5	no	9.770	9.698	EPSD	ICGC;CCLE	6.822	Down-regulation
Atypical_PIKK_FRAP_MTOR_ST	Q00613	HSF1	P42345	MTOR	S275	A278T	278	Missense	distal	3	no	8.306	6.844	EPSD	ICGC	6.822	Down-regulation
Atypical_PIKK_FRAP_MTOR_ST	Q00613	HSF1	P42345	MTOR	S279	A278T	278	Missense	proximal	-1	no	10.095	10.047	EPSD	ICGC	6.822	Down-regulation
Atypical_PIKK_FRAP_MTOR_ST	Q00613	HSF1	P42345	MTOR	S419	S421L	421	Missense	proximal	2	no	14.113	13.918	EPSD	ICGC;COSMIC	6.822	Down-regulation
Atypical_PIKK_FRAP_MTOR_ST	Q00613	HSF1	P42345	MTOR	S419	S419G	419	Missense	central	0	yes	14.113	0.000	EPSD	ICGC;COSMIC	6.822	Loss
Atypical_PIKK_FRAP_MTOR_ST	Q00613	HSF1	P42345	MTOR	S518	A523V	523	Missense	distal	5	no	8.096	8.789	EPSD	ICGC;COSMIC	6.822	Up-regulation
Atypical_PIKK_FRAP_MTOR_ST	Q5T4S7	UBR4	P42345	MTOR	S364	S365P	365	Missense	proximal	1	no	2.901	11.425	EPSD	ICGC;COSMIC	6.822	Gain
Atypical_PIKK_FRAP_MTOR_ST	Q5T4S7	UBR4	P42345	MTOR	S372	Y370C	370	Missense	proximal	-2	no	10.830	11.522	EPSD	ICGC;COSMIC	6.822	Up-regulation
Atypical_PIKK_FRAP_MTOR_ST	Q5T4S7	UBR4	P42345	MTOR	S372	S365P	365	Missense	distal	-7	no	10.830	10.392	EPSD	ICGC;COSMIC	6.822	Down-regulation
Atypical_PIKK_FRAP_MTOR_ST	Q5T4S7	UBR4	P42345	MTOR	S457	R450G	450	Missense	distal	-7	no	7.396	7.593	EPSD	ICGC;COSMIC	6.822	Up-regulation
Atypical_PIKK_FRAP_MTOR_ST	Q5T4S7	UBR4	P42345	MTOR	S555	A560V	560	Missense	distal	5	no	8.973	9.666	EPSD	ICGC;COSMIC	6.822	Up-regulation
Atypical_PIKK_FRAP_MTOR_ST	Q5T4S7	UBR4	P42345	MTOR	S555	S561R	561	Missense	distal	6	no	8.973	7.150	EPSD	ICGC	6.822	Down-regulation
Atypical_PIKK_FRAP_MTOR_ST	Q5T4S7	UBR4	P42345	MTOR	S555	A560D	560	Missense	distal	5	no	8.973	8.579	EPSD	ICGC	6.822	Down-regulation
Atypical_PIKK_FRAP_MTOR_ST	Q5T4S7	UBR4	P42345	MTOR	S555	A562T	562	Missense	distal	7	no	8.973	8.452	EPSD	ICGC;COSMIC	6.822	Down-regulation
Atypical_PIKK_FRAP_MTOR_ST	Q5T4S7	UBR4	P42345	MTOR	S555	G554C	554	Missense	proximal	-1	no	8.973	8.990	EPSD	ICGC;COSMIC	6.822	Up-regulation
Atypical_PIKK_FRAP_MTOR_ST	Q5T4S7	UBR4	P42345	MTOR	T905	S898R	898	Missense	distal	-7	no	8.373	7.614	EPSD	ICGC;COSMIC	6.822	Down-regulation
Atypical_PIKK_FRAP_MTOR_ST	Q5T4S7	UBR4	P42345	MTOR	S1652	E1650D	1650	Missense	proximal	-2	no	6.917	6.503	EPSD	ICGC;COSMIC	6.822	Loss
Atypical_PIKK_FRAP_MTOR_ST	Q5T4S7	UBR4	P42345	MTOR	T1731	L1725F	1725	Missense	distal	-6	no	8.291	8.570	EPSD	ICGC;COSMIC	6.822	Up-regulation
Atypical_PIKK_FRAP_MTOR_ST	Q5T4S7	UBR4	P42345	MTOR	T1731	P1732S	1732	Missense	proximal	1	no	8.291	-0.233	EPSD	ICGC;COSMIC	6.822	Loss
Atypical_PIKK_FRAP_MTOR_ST	Q5T4S7	UBR4	P42345	MTOR	T1731	S1737R	1737	Missense	distal	6	no	8.291	6.468	EPSD	ICGC	6.822	Loss
Atypical_PIKK_FRAP_MTOR_ST	Q5T4S7	UBR4	P42345	MTOR	T1731	T1731N	1731	Missense	central	0	yes	8.291	0.000	EPSD	ICGC	6.822	Loss
Atypical_PIKK_FRAP_MTOR_ST	Q5T4S7	UBR4	P42345	MTOR	T1731	A1726V	1726	Missense	distal	-5	no	8.291	8.201	EPSD	ICGC	6.822	Down-regulation
Atypical_PIKK_FRAP_MTOR_ST	Q5T4S7	UBR4	P42345	MTOR	S1762	R1757C	1757	Missense	distal	-5	no	7.527	7.651	EPSD	ICGC;COSMIC	6.822	Up-regulation
Atypical_PIKK_FRAP_MTOR_ST	Q5T4S7	UBR4	P42345	MTOR	S1904	R1908L	1908	Missense	distal	4	no	10.006	9.939	EPSD	ICGC;COSMIC	6.822	Down-regulation
Atypical_PIKK_FRAP_MTOR_ST	Q5T4S7	UBR4	P42345	MTOR	S2131	A2133E	2133	Missense	proximal	2	no	6.704	8.306	EPSD	ICGC	6.822	Gain
Atypical_PIKK_FRAP_MTOR_ST	Q5T4S7	UBR4	P42345	MTOR	S2131	A2133T	2133	Missense	proximal	2	no	6.704	7.409	EPSD	ICGC;COSMIC	6.822	Gain
Atypical_PIKK_FRAP_MTOR_ST	Q5T4S7	UBR4	P42345	MTOR	T2140	A2133E	2133	Missense	distal	-7	no	6.518	6.954	EPSD	ICGC	6.822	Gain
Atypical_PIKK_FRAP_MTOR_ST	Q5T4S7	UBR4	P42345	MTOR	T2140	A2133T	2133	Missense	distal	-7	no	6.518	7.410	EPSD	ICGC;COSMIC	6.822	Gain
Atypical_PIKK_FRAP_MTOR_ST	Q5T4S7	UBR4	P42345	MTOR	S3316	S3316L	3316	Missense	central	0	yes	11.730	0.000	EPSD	ICGC	6.822	Loss
Atypical_PIKK_FRAP_MTOR_ST	Q5T4S7	UBR4	P42345	MTOR	S3787	S3786Y	3786	Missense	proximal	-1	no	14.299	14.126	EPSD	ICGC	6.822	Down-regulation
Atypical_PIKK_FRAP_MTOR_ST	Q6PKG0	LARP1	P42345	MTOR	S75	P82H	82	Missense	distal	7	no	8.578	9.193	EPSD	ICGC;COSMIC	6.822	Up-regulation
Atypical_PIKK_FRAP_MTOR_ST	Q6PKG0	LARP1	P42345	MTOR	S143	P144Q	144	Missense	proximal	1	no	14.719	6.105	EPSD	ICGC;COSMIC	6.822	Loss
Atypical_PIKK_FRAP_MTOR_ST	Q6PKG0	LARP1	P42345	MTOR	S766	R765S	765	Missense	proximal	-1	no	9.660	9.822	EPSD;PhosphoSitePlus	ICGC	6.822	Up-regulation
Atypical_PIKK_FRAP_MTOR_ST	Q6PKG0	LARP1	P42345	MTOR	S774	S774I	774	Missense	central	0	yes	12.081	0.000	PhosphoSitePlus;EPSD	ICGC	6.822	Loss
Atypical_PIKK_FRAP_MTOR_ST	Q9H5H4	ZNF768	P42345	MTOR	S23	D19E	19	Missense	distal	-4	no	11.283	10.133	EPSD	ICGC;COSMIC	6.822	Down-regulation
Atypical_PIKK_FRAP_MTOR_ST	Q9H5H4	ZNF768	P42345	MTOR	S23	R29I	29	Missense	distal	6	no	11.283	12.241	EPSD	ICGC;COSMIC	6.822	Up-regulation
Atypical_PIKK_FRAP_MTOR_ST	Q9H5H4	ZNF768	P42345	MTOR	S23	P24L	24	Missense	proximal	1	no	11.283	5.314	EPSD	ICGC	6.822	Loss
Atypical_PIKK_FRAP_MTOR_ST	Q9H5H4	ZNF768	P42345	MTOR	S69	S76R	76	Missense	distal	7	no	15.896	16.689	EPSD	ICGC	6.822	Up-regulation
Atypical_PIKK_FRAP_MTOR_ST	Q9H5H4	ZNF768	P42345	MTOR	S76	S76R	76	Missense	central	0	yes	7.904	0.000	EPSD	ICGC	6.822	Loss
Atypical_PIKK_FRAP_MTOR_ST	Q9H5H4	ZNF768	P42345	MTOR	S83	R89Q	89	Missense	distal	6	no	11.657	12.041	EPSD	ICGC;COSMIC	6.822	Up-regulation
Atypical_PIKK_FRAP_MTOR_ST	Q9H5H4	ZNF768	P42345	MTOR	S83	S76R	76	Missense	distal	-7	no	11.657	10.898	EPSD	ICGC	6.822	Down-regulation
Atypical_PIKK_FRAP_MTOR_ST	Q9H5H4	ZNF768	P42345	MTOR	S90	P91R	91	Missense	proximal	1	no	9.700	-0.133	EPSD	ICGC;COSMIC	6.822	Loss
Atypical_PIKK_FRAP_MTOR_ST	Q9H5H4	ZNF768	P42345	MTOR	S90	R89Q	89	Missense	proximal	-1	no	9.700	9.719	EPSD	ICGC;COSMIC	6.822	Up-regulation
Atypical_PIKK_FRAP_MTOR_ST	Q9H5H4	ZNF768	P42345	MTOR	S97	P91R	91	Missense	distal	-6	no	11.915	12.002	EPSD	ICGC;COSMIC	6.822	Up-regulation
Atypical_PIKK_FRAP_MTOR_ST	Q9H5H4	ZNF768	P42345	MTOR	S97	A101V	101	Missense	distal	4	no	11.915	12.077	EPSD	ICGC;COSMIC	6.822	Up-regulation
Atypical_PIKK_FRAP_MTOR_ST	Q9H5H4	ZNF768	P42345	MTOR	S104	A101V	101	Missense	distal	-3	no	12.580	13.209	EPSD	ICGC;COSMIC	6.822	Up-regulation
Atypical_PIKK_FRAP_MTOR_ST	Q9H5H4	ZNF768	P42345	MTOR	S125	S125N	125	Missense	central	0	yes	6.898	0.000	EPSD	ICGC	6.822	Loss
Atypical_PIKK_FRAP_MTOR_ST	Q9H5H4	ZNF768	P42345	MTOR	S132	S125N	125	Missense	distal	-7	no	9.467	9.276	EPSD	ICGC	6.822	Down-regulation
Atypical_PIKK_FRAP_MTOR_ST	Q9H5H4	ZNF768	P42345	MTOR	S274	L276M	276	Missense	proximal	2	no	9.588	8.349	EPSD	ICGC	6.822	Down-regulation
Atypical_PIKK_FRAP_MTOR_ST	Q9H5H4	ZNF768	P42345	MTOR	S274	Q280K	280	Missense	distal	6	no	9.588	10.291	EPSD	ICGC;COSMIC	6.822	Up-regulation
Atypical_PIKK_FRAP_MTOR_ST	Q9H5H4	ZNF768	P42345	MTOR	S330	R334H	334	Missense	distal	4	no	11.094	10.835	EPSD	ICGC	6.822	Down-regulation
Atypical_PIKK_FRAP_MTOR_ST	Q9H5H4	ZNF768	P42345	MTOR	S442	G435S	435	Missense	distal	-7	no	14.328	14.891	EPSD	ICGC;COSMIC;GDSC;CCLE	6.822	Up-regulation
Atypical_PIKK_FRAP_MTOR_ST	Q9H5H4	ZNF768	P42345	MTOR	S442	R437C	437	Missense	distal	-5	no	14.328	14.452	EPSD	ICGC;COSMIC	6.822	Up-regulation
Atypical_PIKK_FRAP_MTOR_ST	Q9H063	MAF1	P42345	MTOR	S60	V55M	55	Missense	distal	-5	no	9.541	9.598	PhosphoSitePlus;EPSD	ICGC;COSMIC	6.822	Up-regulation
Atypical_PIKK_FRAP_MTOR_ST	Q9H063	MAF1	P42345	MTOR	S68	L72F	72	Missense	distal	4	no	10.497	10.893	EPSD;PhosphoSitePlus	ICGC;COSMIC	6.822	Up-regulation
Atypical_PIKK_FRAP_MTOR_ST	Q9H063	MAF1	P42345	MTOR	T245	S244L	244	Missense	proximal	-1	no	13.162	12.961	EPSD	ICGC;COSMIC	6.822	Down-regulation
Atypical_PIKK_FRAP_MTOR_ST	Q9Y2J4	AMOTL2	P42345	MTOR	S50	G47A	47	Missense	distal	-3	no	12.738	11.873	EPSD	ICGC;COSMIC	6.822	Down-regulation
Atypical_PIKK_FRAP_MTOR_ST	Q9Y2J4	AMOTL2	P42345	MTOR	S50	G44V	44	Missense	distal	-6	no	12.738	11.994	EPSD	ICGC	6.822	Down-regulation
Atypical_PIKK_FRAP_MTOR_ST	Q9Y2J4	AMOTL2	P42345	MTOR	S50	S54F	54	Missense	distal	4	no	12.738	12.494	EPSD	ICGC	6.822	Down-regulation
Atypical_PIKK_FRAP_MTOR_ST	Q9Y2J4	AMOTL2	P42345	MTOR	S236	R234S	234	Missense	proximal	-2	no	6.733	6.861	EPSD	ICGC;COSMIC	6.822	Gain
Atypical_PIKK_FRAP_MTOR_ST	Q9Y2J4	AMOTL2	P42345	MTOR	S540	L546M	546	Missense	distal	6	no	11.791	11.597	EPSD	ICGC	6.822	Down-regulation
Atypical_PIKK_FRAP_MTOR_ST	Q9Y2J4	AMOTL2	P42345	MTOR	S759	L760V	760	Missense	proximal	1	no	9.248	8.496	PhosphoSitePlus	ICGC;COSMIC	6.822	Down-regulation
Atypical_PIKK_FRAP_MTOR_ST	Q9Y2J4	AMOTL2	P42345	MTOR	S759	L760M	760	Missense	proximal	1	no	9.248	9.285	PhosphoSitePlus	ICGC;COSMIC	6.822	Up-regulation
Atypical_PIKK_FRAP_MTOR_ST	Q9Y2J4	AMOTL2	P42345	MTOR	S762	L760V	760	Missense	proximal	-2	no	11.749	11.965	EPSD	ICGC;COSMIC	6.822	Up-regulation
Atypical_PIKK_FRAP_MTOR_ST	Q9Y2J4	AMOTL2	P42345	MTOR	S762	L760M	760	Missense	proximal	-2	no	11.749	11.359	EPSD	ICGC;COSMIC	6.822	Down-regulation
Atypical_PIKK_FRAP_MTOR_ST	Q9Y2J4	AMOTL2	P42345	MTOR	S766	L760V	760	Missense	distal	-6	no	9.032	9.165	EPSD	ICGC;COSMIC	6.822	Up-regulation
Atypical_PIKK_FRAP_MTOR_ST	Q9Y2J4	AMOTL2	P42345	MTOR	S766	D773E	773	Missense	distal	7	no	9.032	8.020	EPSD	ICGC	6.822	Down-regulation
Atypical_PIKK_FRAP_MTOR_ST	Q9Y2J4	AMOTL2	P42345	MTOR	S766	L760M	760	Missense	distal	-6	no	9.032	9.798	EPSD	ICGC;COSMIC	6.822	Up-regulation
Atypical_PIKK_FRAP_MTOR_ST	P04198	MYCN	P42345	MTOR	S62	E69K	69	Missense	distal	7	no	11.056	11.152	PhosphoSitePlus	ICGC;COSMIC	6.822	Up-regulation
Atypical_PIKK_FRAP_MTOR_ST	P04198	MYCN	P42345	MTOR	S369	S369I	369	Missense	central	0	yes	8.029	0.000	EPSD	ICGC	6.822	Loss
Atypical_PIKK_FRAP_MTOR_ST	P04198	MYCN	P42345	MTOR	S369	S369R	369	Missense	central	0	yes	8.029	0.000	EPSD	ICGC;COSMIC	6.822	Loss
Atypical_PIKK_FRAP_MTOR_ST	P04198	MYCN	P42345	MTOR	S371	S369I	369	Missense	proximal	-2	no	9.494	9.054	EPSD	ICGC	6.822	Down-regulation
Atypical_PIKK_FRAP_MTOR_ST	P04198	MYCN	P42345	MTOR	S371	S369R	369	Missense	proximal	-2	no	9.494	9.366	EPSD	ICGC;COSMIC	6.822	Down-regulation
Atypical_PIKK_FRAP_MTOR_ST	P04198	MYCN	P42345	MTOR	S377	R382H	382	Missense	distal	5	no	7.775	8.080	EPSD	ICGC;COSMIC	6.822	Up-regulation
Atypical_PIKK_FRAP_MTOR_ST	P04198	MYCN	P42345	MTOR	S377	D379G	379	Missense	proximal	2	no	7.775	7.738	EPSD	ICGC;COSMIC	6.822	Down-regulation
Atypical_PIKK_FRAP_MTOR_ST	Q9H4A3	WNK1	P42345	MTOR	S11	T12A	12	Missense	proximal	1	no	8.560	5.948	EPSD	ICGC;COSMIC	6.822	Loss
Atypical_PIKK_FRAP_MTOR_ST	Q9H4A3	WNK1	P42345	MTOR	S19	P23L	23	Missense	distal	4	no	14.268	13.884	EPSD	ICGC;COSMIC	6.822	Down-regulation
Atypical_PIKK_FRAP_MTOR_ST	Q9H4A3	WNK1	P42345	MTOR	S19	T12A	12	Missense	distal	-7	no	14.268	13.376	EPSD	ICGC;COSMIC	6.822	Down-regulation
Atypical_PIKK_FRAP_MTOR_ST	Q9H4A3	WNK1	P42345	MTOR	S19	K26N	26	Missense	distal	7	no	14.268	15.220	EPSD	ICGC	6.822	Up-regulation
Atypical_PIKK_FRAP_MTOR_ST	Q9H4A3	WNK1	P42345	MTOR	S1899	S1899F	1899	Missense	central	0	yes	10.216	0.000	EPSD	ICGC	6.822	Loss
Other_NEK_NEK6_NEK6_ST	O95235	KIF20A	Q9HC98	NEK6	S104	S109I	109	Missense	distal	5	no	90.928	88.260	EPSD	ICGC;COSMIC	73.015	Down-regulation
Other_NEK_NEK6_NEK6_ST	O95235	KIF20A	Q9HC98	NEK6	S677	R675W	675	Missense	proximal	-2	no	76.103	75.780	EPSD	ICGC;COSMIC;GDSC	73.015	Down-regulation
Other_NEK_NEK6_NEK6_ST	O95235	KIF20A	Q9HC98	NEK6	S754	A758S	758	Missense	distal	4	no	116.554	114.373	PhosphoSitePlus;EPSD	ICGC	73.015	Down-regulation
Other_NEK_NEK6_NEK6_ST	O95235	KIF20A	Q9HC98	NEK6	T857	S863T	863	Missense	distal	6	no	76.426	76.250	EPSD	ICGC;COSMIC	73.015	Down-regulation
Other_NEK_NEK6_NEK6_ST	O95235	KIF20A	Q9HC98	NEK6	S883	R876L	876	Missense	distal	-7	no	110.050	109.934	EPSD;PhosphoSitePlus	ICGC;COSMIC	73.015	Down-regulation
Other_NEK_NEK6_NEK6_ST	P23443	RPS6KB1	Q9HC98	NEK6	S53	S53I	53	Missense	central	0	yes	115.946	0.000	EPSD;PhosphoSitePlus	ICGC	73.015	Loss
Other_NEK_NEK6_NEK6_ST	P23443	RPS6KB1	Q9HC98	NEK6	S75	I74M	74	Missense	proximal	-1	no	71.082	76.517	EPSD	ICGC;COSMIC	73.015	Gain
Other_NEK_NEK6_NEK6_ST	P23443	RPS6KB1	Q9HC98	NEK6	S441	P445T	445	Missense	distal	4	no	74.133	73.710	EPSD	ICGC;COSMIC	73.015	Down-regulation
Other_NEK_NEK6_NEK6_ST	P23443	RPS6KB1	Q9HC98	NEK6	S441	S441N	441	Missense	central	0	yes	74.133	0.000	EPSD	ICGC;COSMIC	73.015	Loss
Other_NEK_NEK6_NEK6_ST	O00141	SGK1	Q9HC98	NEK6	S61	L58V	58	Missense	distal	-3	no	84.877	29.640	EPSD	ICGC;COSMIC	73.015	Loss
Other_NEK_NEK6_NEK6_ST	O00141	SGK1	Q9HC98	NEK6	S61	L68V	68	Missense	distal	7	no	84.877	83.578	EPSD	ICGC;COSMIC;CCLE	73.015	Down-regulation
Other_NEK_NEK6_NEK6_ST	O00141	SGK1	Q9HC98	NEK6	S61	V54L	54	Missense	distal	-7	no	84.877	84.855	EPSD	ICGC;COSMIC	73.015	Down-regulation
Other_NEK_NEK6_NEK6_ST	O00141	SGK1	Q9HC98	NEK6	S61	K59E	59	Missense	proximal	-2	no	84.877	78.567	EPSD	ICGC;COSMIC	73.015	Down-regulation
Other_NEK_NEK6_NEK6_ST	O00141	SGK1	Q9HC98	NEK6	S61	E65G	65	Missense	distal	4	no	84.877	82.827	EPSD	ICGC;COSMIC	73.015	Down-regulation
Other_NEK_NEK6_NEK6_ST	O00141	SGK1	Q9HC98	NEK6	S61	Q64H	64	Missense	distal	3	no	84.877	84.925	EPSD	ICGC;COSMIC	73.015	Up-regulation
Other_NEK_NEK6_NEK6_ST	O00141	SGK1	Q9HC98	NEK6	S61	Q62K	62	Missense	proximal	1	no	84.877	85.649	EPSD	ICGC	73.015	Up-regulation
Other_NEK_NEK6_NEK6_ST	O00141	SGK1	Q9HC98	NEK6	S61	L58F	58	Missense	distal	-3	no	84.877	71.741	EPSD	ICGC;COSMIC	73.015	Loss
Other_NEK_NEK6_NEK6_ST	O00141	SGK1	Q9HC98	NEK6	S61	E67D	67	Missense	distal	6	no	84.877	85.172	EPSD	ICGC	73.015	Up-regulation
Other_NEK_NEK6_NEK6_ST	O00141	SGK1	Q9HC98	NEK6	S61	P63R	63	Missense	proximal	2	no	84.877	84.300	EPSD	ICGC;CCLE	73.015	Down-regulation
Other_NEK_NEK6_NEK6_ST	O00141	SGK1	Q9HC98	NEK6	S61	P63A	63	Missense	proximal	2	no	84.877	82.957	EPSD	ICGC	73.015	Down-regulation
Other_NEK_NEK6_NEK6_ST	O00141	SGK1	Q9HC98	NEK6	S61	E65V	65	Missense	distal	4	no	84.877	83.922	EPSD	ICGC	73.015	Down-regulation
Other_NEK_NEK6_NEK6_ST	O00141	SGK1	Q9HC98	NEK6	S61	S56C	56	Missense	distal	-5	no	84.877	85.282	EPSD	ICGC	73.015	Up-regulation
Other_NEK_NEK6_NEK6_ST	O00141	SGK1	Q9HC98	NEK6	S61	V54I	54	Missense	distal	-7	no	84.877	84.630	EPSD	ICGC;COSMIC;CCLE	73.015	Down-regulation
Other_NEK_NEK6_NEK6_ST	O00141	SGK1	Q9HC98	NEK6	S61	P63H	63	Missense	proximal	2	no	84.877	85.224	EPSD	ICGC	73.015	Up-regulation
Other_NEK_NEK6_NEK6_ST	O00141	SGK1	Q9HC98	NEK6	S74	A71P	71	Missense	distal	-3	no	0.778	76.772	EPSD	ICGC	73.015	Gain
Other_NEK_NEK6_NEK6_ST	O00141	SGK1	Q9HC98	NEK6	S88	P95L	95	Missense	distal	7	no	86.103	87.123	EPSD	ICGC;COSMIC	73.015	Up-regulation
Other_NEK_NEK6_NEK6_ST	O00141	SGK1	Q9HC98	NEK6	S88	P95Q	95	Missense	distal	7	no	86.103	86.299	EPSD	ICGC	73.015	Up-regulation
Other_NEK_NEK6_NEK6_ST	O00141	SGK1	Q9HC98	NEK6	S88	P95A	95	Missense	distal	7	no	86.103	86.902	EPSD	ICGC	73.015	Up-regulation
Other_NEK_NEK6_NEK6_ST	O00141	SGK1	Q9HC98	NEK6	S88	G86D	86	Missense	proximal	-2	no	86.103	82.628	EPSD	ICGC;COSMIC	73.015	Down-regulation
Other_NEK_NEK6_NEK6_ST	O00141	SGK1	Q9HC98	NEK6	S88	P91H	91	Missense	distal	3	no	86.103	86.143	EPSD	ICGC	73.015	Up-regulation
Other_NEK_NEK6_NEK6_ST	O00141	SGK1	Q9HC98	NEK6	S377	R383Q	383	Missense	distal	6	no	102.912	102.929	PhosphoSitePlus;EPSD	ICGC;COSMIC	73.015	Up-regulation
Other_NEK_NEK6_NEK6_ST	O00141	SGK1	Q9HC98	NEK6	S377	N380I	380	Missense	distal	3	no	102.912	103.063	PhosphoSitePlus;EPSD	ICGC;COSMIC	73.015	Up-regulation
Other_NEK_NEK6_NEK6_ST	O00141	SGK1	Q9HC98	NEK6	S377	P379T	379	Missense	proximal	2	no	102.912	100.419	PhosphoSitePlus;EPSD	ICGC;COSMIC	73.015	Down-regulation
Other_NEK_NEK6_NEK6_ST	O00141	SGK1	Q9HC98	NEK6	S422	G420C	420	Missense	proximal	-2	no	110.430	99.323	EPSD;PhosphoSitePlus	ICGC;COSMIC	73.015	Down-regulation
Other_NEK_NEK6_NEK6_ST	O00141	SGK1	Q9HC98	NEK6	S422	F418L	418	Missense	distal	-4	no	110.430	111.088	EPSD;PhosphoSitePlus	ICGC	73.015	Up-regulation
Other_NEK_NEK6_NEK6_ST	O00141	SGK1	Q9HC98	NEK6	S422	E416K	416	Missense	distal	-6	no	110.430	110.626	EPSD;PhosphoSitePlus	ICGC;COSMIC	73.015	Up-regulation
Other_NEK_NEK6_NEK6_ST	O00141	SGK1	Q9HC98	NEK6	S422	A424V	424	Missense	proximal	2	no	110.430	110.733	EPSD;PhosphoSitePlus	ICGC;COSMIC	73.015	Up-regulation
Other_NEK_NEK6_NEK6_ST	O00141	SGK1	Q9HC98	NEK6	S422	F418C	418	Missense	distal	-4	no	110.430	109.993	EPSD;PhosphoSitePlus	ICGC;COSMIC	73.015	Down-regulation
Other_NEK_NEK6_NEK6_ST	Q08345	DDR1	Q9HC98	NEK6	T469	H462Y	462	Missense	distal	-7	no	82.075	81.964	EPSD	ICGC;COSMIC	73.015	Down-regulation
Other_NEK_NEK6_NEK6_ST	Q08345	DDR1	Q9HC98	NEK6	S509	S504C	504	Missense	distal	-5	no	79.836	80.242	EPSD	ICGC;COSMIC	73.015	Up-regulation
Other_NEK_NEK6_NEK6_ST	Q08345	DDR1	Q9HC98	NEK6	S509	R514C	514	Missense	distal	5	no	79.836	78.419	EPSD	ICGC;COSMIC	73.015	Down-regulation
Other_NEK_NEK6_NEK6_ST	Q96AP0	ACD	Q9HC98	NEK6	S510	V515A	515	Missense	distal	5	no	76.360	76.481	EPSD	ICGC;COSMIC	73.015	Up-regulation
Other_NEK_NEK6_NEK6_ST	Q96AP0	ACD	Q9HC98	NEK6	S510	V515L	515	Missense	distal	5	no	76.360	75.222	EPSD	ICGC;COSMIC	73.015	Down-regulation
Other_NEK_NEK6_NEK6_ST	Q08999	RBL2	Q9HC98	NEK6	S40	E39K	39	Missense	proximal	-1	no	75.408	79.328	EPSD	ICGC;COSMIC	73.015	Up-regulation
Other_NEK_NEK6_NEK6_ST	Q08999	RBL2	Q9HC98	NEK6	S40	A38S	38	Missense	proximal	-2	no	75.408	80.491	EPSD	ICGC	73.015	Up-regulation
Other_NEK_NEK6_NEK6_ST	Q08999	RBL2	Q9HC98	NEK6	S40	Q46K	46	Missense	distal	6	no	75.408	75.933	EPSD	ICGC;COSMIC	73.015	Up-regulation
Other_NEK_NEK6_NEK6_ST	Q08999	RBL2	Q9HC98	NEK6	S40	P36L	36	Missense	distal	-4	no	75.408	76.470	EPSD	ICGC;COSMIC	73.015	Up-regulation
Other_NEK_NEK6_NEK6_ST	Q08999	RBL2	Q9HC98	NEK6	S98	C95F	95	Missense	distal	-3	no	33.046	73.273	EPSD	ICGC;COSMIC	73.015	Gain
Other_NEK_NEK6_NEK6_ST	Q08999	RBL2	Q9HC98	NEK6	S659	T653A	653	Missense	distal	-6	no	114.357	114.280	PhosphoSitePlus	ICGC;COSMIC	73.015	Down-regulation
Other_NEK_NEK6_NEK6_ST	Q08999	RBL2	Q9HC98	NEK6	S861	C855Y	855	Missense	distal	-6	no	86.088	85.985	EPSD	ICGC;COSMIC	73.015	Down-regulation
Other_NEK_NEK6_NEK6_ST	Q08999	RBL2	Q9HC98	NEK6	S1035	A1031G	1031	Missense	distal	-4	no	73.595	74.276	EPSD	ICGC;COSMIC	73.015	Up-regulation
Other_NEK_NEK6_NEK6_ST	P52948	NUP98	Q9HC98	NEK6	S231	P232S	232	Missense	proximal	1	no	73.361	69.664	EPSD	ICGC;COSMIC;GDSC;CCLE	73.015	Loss
Other_NEK_NEK6_NEK6_ST	P52948	NUP98	Q9HC98	NEK6	S231	T238K	238	Missense	distal	7	no	73.361	72.806	EPSD	ICGC	73.015	Loss
Other_NEK_NEK6_NEK6_ST	P52948	NUP98	Q9HC98	NEK6	S231	T225N	225	Missense	distal	-6	no	73.361	73.266	EPSD	ICGC	73.015	Down-regulation
Other_NEK_NEK6_NEK6_ST	P52948	NUP98	Q9HC98	NEK6	S231	T238I	238	Missense	distal	7	no	73.361	74.668	EPSD	ICGC;COSMIC	73.015	Up-regulation
Other_NEK_NEK6_NEK6_ST	P52948	NUP98	Q9HC98	NEK6	S243	T238K	238	Missense	distal	-5	no	88.975	88.544	EPSD	ICGC	73.015	Down-regulation
Other_NEK_NEK6_NEK6_ST	P52948	NUP98	Q9HC98	NEK6	S243	T238I	238	Missense	distal	-5	no	88.975	89.189	EPSD	ICGC;COSMIC	73.015	Up-regulation
Other_NEK_NEK6_NEK6_ST	P52948	NUP98	Q9HC98	NEK6	S244	T238K	238	Missense	distal	-6	no	77.772	77.773	EPSD	ICGC	73.015	Up-regulation
Other_NEK_NEK6_NEK6_ST	P52948	NUP98	Q9HC98	NEK6	S244	T238I	238	Missense	distal	-6	no	77.772	77.437	EPSD	ICGC;COSMIC	73.015	Down-regulation
Other_NEK_NEK6_NEK6_ST	P52948	NUP98	Q9HC98	NEK6	S839	D845A	845	Missense	distal	6	no	111.564	111.523	EPSD	ICGC;COSMIC	73.015	Down-regulation
Other_NEK_NEK6_NEK6_ST	P52948	NUP98	Q9HC98	NEK6	S839	T832I	832	Missense	distal	-7	no	111.564	111.162	EPSD	ICGC;COSMIC	73.015	Down-regulation
Other_NEK_NEK6_NEK6_ST	P52948	NUP98	Q9HC98	NEK6	S878	G871C	871	Missense	distal	-7	no	77.278	77.236	EPSD	ICGC;COSMIC	73.015	Down-regulation
Other_NEK_NEK6_NEK6_ST	P52948	NUP98	Q9HC98	NEK6	S913	S913R	913	Missense	central	0	yes	88.721	0.000	EPSD	ICGC;COSMIC	73.015	Loss
Other_NEK_NEK6_NEK6_ST	P52948	NUP98	Q9HC98	NEK6	S913	Q914H	914	Missense	proximal	1	no	88.721	91.006	EPSD	ICGC;COSMIC	73.015	Up-regulation
Other_NEK_NEK6_NEK6_ST	P52948	NUP98	Q9HC98	NEK6	S913	A907V	907	Missense	distal	-6	no	88.721	88.742	EPSD	ICGC;COSMIC	73.015	Up-regulation
Other_NEK_NEK6_NEK6_ST	P52948	NUP98	Q9HC98	NEK6	S913	S913N	913	Missense	central	0	yes	88.721	0.000	EPSD	ICGC;COSMIC	73.015	Loss
Other_NEK_NEK6_NEK6_ST	P50613	CDK7	Q9HC98	NEK6	S217	T223A	223	Missense	distal	6	no	80.732	80.797	EPSD	ICGC;COSMIC	73.015	Up-regulation
Other_NEK_NEK6_NEK6_ST	P40763	STAT3	Q9HC98	NEK6	T433	L438P	438	Missense	distal	5	no	79.952	79.067	EPSD	ICGC;COSMIC	73.015	Down-regulation
Other_NEK_NEK6_NEK6_ST	P40763	STAT3	Q9HC98	NEK6	S727	L724P	724	Missense	distal	-3	no	112.082	105.650	PhosphoSitePlus	ICGC;COSMIC	73.015	Down-regulation
Other_NEK_NEK6_NEK6_ST	P40763	STAT3	Q9HC98	NEK6	S727	S727P	727	Missense	central	0	yes	112.082	0.000	PhosphoSitePlus	ICGC	73.015	Loss
Other_NEK_NEK6_NEK6_ST	P40763	STAT3	Q9HC98	NEK6	S727	L734S	734	Missense	distal	7	no	112.082	111.643	PhosphoSitePlus	ICGC;COSMIC	73.015	Down-regulation
Other_NEK_NEK6_NEK6_ST	Q05586	GRIN1	Q9HC98	NEK6	S14	A10T	10	Missense	distal	-4	no	74.181	74.866	EPSD	ICGC	73.015	Up-regulation
Other_NEK_NEK6_NEK6_ST	Q05586	GRIN1	Q9HC98	NEK6	S14	R19H	19	Missense	distal	5	no	74.181	73.456	EPSD	ICGC;COSMIC	73.015	Down-regulation
Other_NEK_NEK6_NEK6_ST	Q05586	GRIN1	Q9HC98	NEK6	S14	A10S	10	Missense	distal	-4	no	74.181	74.893	EPSD	ICGC;COSMIC	73.015	Up-regulation
Other_NEK_NEK6_NEK6_ST	Q05586	GRIN1	Q9HC98	NEK6	T122	G120R	120	Missense	proximal	-2	no	83.571	72.219	EPSD	ICGC;COSMIC	73.015	Loss
Other_NEK_NEK6_NEK6_ST	Q05586	GRIN1	Q9HC98	NEK6	T122	R115S	115	Missense	distal	-7	no	83.571	83.593	EPSD	ICGC;COSMIC	73.015	Up-regulation
Other_NEK_NEK6_NEK6_ST	Q05586	GRIN1	Q9HC98	NEK6	T122	R124H	124	Missense	proximal	2	no	83.571	84.496	EPSD	ICGC;COSMIC	73.015	Up-regulation
Other_NEK_NEK6_NEK6_ST	Q05586	GRIN1	Q9HC98	NEK6	T122	R115L	115	Missense	distal	-7	no	83.571	83.455	EPSD	ICGC;COSMIC	73.015	Down-regulation
Other_NEK_NEK6_NEK6_ST	Q05586	GRIN1	Q9HC98	NEK6	T442	T437N	437	Missense	distal	-5	no	79.464	79.201	EPSD	ICGC;COSMIC	73.015	Down-regulation
Other_NEK_NEK6_NEK6_ST	Q05586	GRIN1	Q9HC98	NEK6	T442	T437S	437	Missense	distal	-5	no	79.464	79.297	EPSD	ICGC	73.015	Down-regulation
Other_NEK_NEK6_NEK6_ST	Q05586	GRIN1	Q9HC98	NEK6	T442	P444L	444	Missense	proximal	2	no	79.464	76.674	EPSD	ICGC	73.015	Down-regulation
Other_NEK_NEK6_NEK6_ST	Q05586	GRIN1	Q9HC98	NEK6	S775	V772F	772	Missense	distal	-3	no	38.427	80.528	EPSD	ICGC	73.015	Gain
Other_NEK_NEK6_NEK6_ST	Q05586	GRIN1	Q9HC98	NEK6	S890	R895M	895	Missense	distal	5	no	109.486	108.558	PhosphoSitePlus	ICGC;COSMIC	73.015	Down-regulation
Other_NEK_NEK6_NEK6_ST	P0DMV8	HSPA1A	Q9HC98	NEK6	S608	N604D	604	Missense	distal	-4	no	74.623	75.091	EPSD	ICGC;COSMIC	73.015	Up-regulation
CK1_CK1_CK1-A_CSNK1A1_ST	P02730	SLC4A1	P48729	CSNK1A1	S29	P27L	27	Missense	proximal	-2	no	20.959	19.975	EPSD	ICGC;COSMIC	20.411	Loss
CK1_CK1_CK1-A_CSNK1A1_ST	P02730	SLC4A1	P48729	CSNK1A1	S303	E306V	306	Missense	distal	3	no	20.723	17.556	PhosphoSitePlus;EPSD	ICGC	20.411	Loss
CK1_CK1_CK1-A_CSNK1A1_ST	P02730	SLC4A1	P48729	CSNK1A1	S402	Q404H	404	Missense	proximal	2	no	22.377	21.360	EPSD	ICGC;COSMIC	20.411	Down-regulation
CK1_CK1_CK1-A_CSNK1A1_ST	P02730	SLC4A1	P48729	CSNK1A1	S402	V405A	405	Missense	distal	3	no	22.377	22.732	EPSD	ICGC;COSMIC	20.411	Up-regulation
CK1_CK1_CK1-A_CSNK1A1_ST	P02730	SLC4A1	P48729	CSNK1A1	S402	A407S	407	Missense	distal	5	no	22.377	22.059	EPSD	ICGC;COSMIC	20.411	Down-regulation
CK1_CK1_CK1-A_CSNK1A1_ST	P17302	GJA1	P48729	CSNK1A1	S244	V240G	240	Missense	distal	-4	no	17.938	20.887	EPSD	ICGC;COSMIC	20.411	Gain
CK1_CK1_CK1-A_CSNK1A1_ST	P17302	GJA1	P48729	CSNK1A1	S325	S328P	328	Missense	distal	3	no	22.566	18.301	EPSD;PhosphoSitePlus	ICGC;COSMIC	20.411	Loss
CK1_CK1_CK1-A_CSNK1A1_ST	P17302	GJA1	P48729	CSNK1A1	S325	A323T	323	Missense	proximal	-2	no	22.566	22.393	EPSD;PhosphoSitePlus	ICGC	20.411	Down-regulation
CK1_CK1_CK1-A_CSNK1A1_ST	P17302	GJA1	P48729	CSNK1A1	S325	A323V	323	Missense	proximal	-2	no	22.566	21.169	EPSD;PhosphoSitePlus	ICGC;COSMIC;CCLE	20.411	Down-regulation
CK1_CK1_CK1-A_CSNK1A1_ST	P17302	GJA1	P48729	CSNK1A1	S328	S328P	328	Missense	central	0	yes	24.471	0.000	EPSD;PhosphoSitePlus	ICGC;COSMIC	20.411	Loss
CK1_CK1_CK1-A_CSNK1A1_ST	P17302	GJA1	P48729	CSNK1A1	S328	A323T	323	Missense	distal	-5	no	24.471	25.151	EPSD;PhosphoSitePlus	ICGC	20.411	Up-regulation
CK1_CK1_CK1-A_CSNK1A1_ST	P17302	GJA1	P48729	CSNK1A1	S328	A323V	323	Missense	distal	-5	no	24.471	24.023	EPSD;PhosphoSitePlus	ICGC;COSMIC;CCLE	20.411	Down-regulation
CK1_CK1_CK1-A_CSNK1A1_ST	P27348	YWHAQ	P48729	CSNK1A1	S37	G33D	33	Missense	distal	-4	no	21.769	22.598	EPSD	ICGC	20.411	Up-regulation
CK1_CK1_CK1-A_CSNK1A1_ST	P27348	YWHAQ	P48729	CSNK1A1	S37	L43M	43	Missense	distal	6	no	21.769	21.988	EPSD	ICGC;COSMIC	20.411	Up-regulation
CK1_CK1_CK1-A_CSNK1A1_ST	P27348	YWHAQ	P48729	CSNK1A1	S210	N207S	207	Missense	distal	-3	no	15.810	20.719	EPSD	ICGC;COSMIC	20.411	Gain
CK1_CK1_CK1-A_CSNK1A1_ST	Q13148	TARDBP	P48729	CSNK1A1	S242	E246D	246	Missense	distal	4	no	26.009	25.938	EPSD;PhosphoSitePlus	ICGC	20.411	Down-regulation
CK1_CK1_CK1-A_CSNK1A1_ST	Q13148	TARDBP	P48729	CSNK1A1	S242	A240V	240	Missense	proximal	-2	no	26.009	24.611	EPSD;PhosphoSitePlus	ICGC;COSMIC;GDSC;CCLE	20.411	Down-regulation
CK1_CK1_CK1-A_CSNK1A1_ST	Q13148	TARDBP	P48729	CSNK1A1	S258	S258C	258	Missense	central	0	yes	20.701	0.000	EPSD	ICGC	20.411	Loss
CK1_CK1_CK1-A_CSNK1A1_ST	Q13148	TARDBP	P48729	CSNK1A1	S258	G252C	252	Missense	distal	-6	no	20.701	19.707	EPSD	ICGC	20.411	Loss
CK1_CK1_CK1-A_CSNK1A1_ST	Q13148	TARDBP	P48729	CSNK1A1	S258	A260V	260	Missense	proximal	2	no	20.701	20.258	EPSD	ICGC	20.411	Loss
CK1_CK1_CK1-A_CSNK1A1_ST	P98177	FOXO4	P48729	CSNK1A1	S146	S147R	147	Missense	proximal	1	no	28.504	28.451	EPSD	ICGC;COSMIC	20.411	Down-regulation
CK1_CK1_CK1-A_CSNK1A1_ST	P98177	FOXO4	P48729	CSNK1A1	S153	S147R	147	Missense	distal	-6	no	23.864	23.336	EPSD	ICGC;COSMIC	20.411	Down-regulation
CK1_CK1_CK1-A_CSNK1A1_ST	P98177	FOXO4	P48729	CSNK1A1	S197	A195T	195	Missense	proximal	-2	no	20.505	20.331	EPSD	ICGC;COSMIC	20.411	Loss
CK1_CK1_CK1-A_CSNK1A1_ST	Q9Y2W7	KCNIP3	P48729	CSNK1A1	S14	L16V	16	Missense	proximal	2	no	21.452	21.164	EPSD	ICGC;COSMIC	20.411	Down-regulation
CK1_CK1_CK1-A_CSNK1A1_ST	Q9BXL7	CARD11	P48729	CSNK1A1	S466	G463W	463	Missense	distal	-3	no	19.685	20.420	EPSD	ICGC;COSMIC	20.411	Gain
CK1_CK1_CK1-A_CSNK1A1_ST	Q9BXL7	CARD11	P48729	CSNK1A1	S537	A534S	534	Missense	distal	-3	no	17.548	22.004	EPSD	ICGC;COSMIC	20.411	Gain
CK1_CK1_CK1-A_CSNK1A1_ST	Q9BXL7	CARD11	P48729	CSNK1A1	S538	A534S	534	Missense	distal	-4	no	19.459	21.059	EPSD	ICGC;COSMIC	20.411	Gain
CK1_CK1_CK1-A_CSNK1A1_ST	Q9BXL7	CARD11	P48729	CSNK1A1	S541	N546K	546	Missense	distal	5	no	22.394	22.384	EPSD	ICGC	20.411	Down-regulation
CK1_CK1_CK1-A_CSNK1A1_ST	Q9BXL7	CARD11	P48729	CSNK1A1	S541	A534S	534	Missense	distal	-7	no	22.394	21.871	EPSD	ICGC;COSMIC	20.411	Down-regulation
CK1_CK1_CK1-A_CSNK1A1_ST	Q9BXL7	CARD11	P48729	CSNK1A1	S559	A565S	565	Missense	distal	6	no	20.325	20.683	EPSD	ICGC;COSMIC	20.411	Gain
CK1_CK1_CK1-A_CSNK1A1_ST	Q9BXL7	CARD11	P48729	CSNK1A1	S559	Q552K	552	Missense	distal	-7	no	20.325	21.020	EPSD	ICGC	20.411	Gain
CK1_CK1_CK1-A_CSNK1A1_ST	Q9BXL7	CARD11	P48729	CSNK1A1	S562	A565S	565	Missense	distal	3	no	19.878	22.108	EPSD	ICGC;COSMIC	20.411	Gain
CK1_CK1_CK1-A_CSNK1A1_ST	Q9BXL7	CARD11	P48729	CSNK1A1	S593	D590E	590	Missense	distal	-3	no	20.489	18.014	EPSD	ICGC	20.411	Loss
CK1_CK1_CK1-A_CSNK1A1_ST	Q9BXL7	CARD11	P48729	CSNK1A1	S593	S593N	593	Missense	central	0	yes	20.489	0.000	EPSD	ICGC;COSMIC	20.411	Loss
CK1_CK1_CK1-A_CSNK1A1_ST	Q9BXL7	CARD11	P48729	CSNK1A1	S618	H623Q	623	Missense	distal	5	no	21.130	20.533	EPSD	ICGC	20.411	Down-regulation
CK1_CK1_CK1-A_CSNK1A1_ST	Q9BXL7	CARD11	P48729	CSNK1A1	S618	S625Y	625	Missense	distal	7	no	21.130	21.384	EPSD	ICGC;COSMIC	20.411	Up-regulation
CK1_CK1_CK1-A_CSNK1A1_ST	Q9BXL7	CARD11	P48729	CSNK1A1	S618	S620F	620	Missense	proximal	2	no	21.130	20.108	EPSD	ICGC	20.411	Loss
CK1_CK1_CK1-A_CSNK1A1_ST	Q9BXL7	CARD11	P48729	CSNK1A1	S621	H623Q	623	Missense	proximal	2	no	20.800	21.816	EPSD	ICGC	20.411	Up-regulation
CK1_CK1_CK1-A_CSNK1A1_ST	Q9BXL7	CARD11	P48729	CSNK1A1	S621	S625Y	625	Missense	distal	4	no	20.800	20.657	EPSD	ICGC;COSMIC	20.411	Down-regulation
CK1_CK1_CK1-A_CSNK1A1_ST	Q9BXL7	CARD11	P48729	CSNK1A1	S621	S620F	620	Missense	proximal	-1	no	20.800	20.097	EPSD	ICGC	20.411	Loss
CK1_CK1_CK1-A_CSNK1A1_ST	Q9BXL7	CARD11	P48729	CSNK1A1	S622	H623Q	623	Missense	proximal	1	no	22.741	23.167	EPSD	ICGC	20.411	Up-regulation
CK1_CK1_CK1-A_CSNK1A1_ST	Q9BXL7	CARD11	P48729	CSNK1A1	S622	S625Y	625	Missense	distal	3	no	22.741	19.936	EPSD	ICGC;COSMIC	20.411	Loss
CK1_CK1_CK1-A_CSNK1A1_ST	Q9BXL7	CARD11	P48729	CSNK1A1	S622	S620F	620	Missense	proximal	-2	no	22.741	20.874	EPSD	ICGC	20.411	Down-regulation
CK1_CK1_CK1-A_CSNK1A1_ST	Q9BXL7	CARD11	P48729	CSNK1A1	S625	H623Q	623	Missense	proximal	-2	no	20.062	22.190	EPSD	ICGC	20.411	Gain
CK1_CK1_CK1-A_CSNK1A1_ST	Q9BXL7	CARD11	P48729	CSNK1A1	S879	E876K	876	Missense	distal	-3	no	23.417	19.497	EPSD	ICGC;COSMIC	20.411	Loss
CK1_CK1_CK1-A_CSNK1A1_ST	Q9BXL7	CARD11	P48729	CSNK1A1	S879	A877E	877	Missense	proximal	-2	no	23.417	24.375	EPSD	ICGC;COSMIC	20.411	Up-regulation
CK1_CK1_CK1-A_CSNK1A1_ST	Q9BXL7	CARD11	P48729	CSNK1A1	S952	E951Q	951	Missense	proximal	-1	no	21.761	21.236	EPSD	ICGC;COSMIC	20.411	Down-regulation
CK1_CK1_CK1-A_CSNK1A1_ST	Q9BXL7	CARD11	P48729	CSNK1A1	S952	S959R	959	Missense	distal	7	no	21.761	21.868	EPSD	ICGC	20.411	Up-regulation
CK1_CK1_CK1-A_CSNK1A1_ST	Q9BXL7	CARD11	P48729	CSNK1A1	S952	E946K	946	Missense	distal	-6	no	21.761	21.483	EPSD	ICGC	20.411	Down-regulation
CK1_CK1_CK1-A_CSNK1A1_ST	P18846	ATF1	P48729	CSNK1A1	S36	Q42K	42	Missense	distal	6	no	21.391	21.284	EPSD;PhosphoSitePlus	ICGC;COSMIC	20.411	Down-regulation
CK1_CK1_CK1-A_CSNK1A1_ST	P18846	ATF1	P48729	CSNK1A1	S36	Q30K	30	Missense	distal	-6	no	21.391	20.782	EPSD;PhosphoSitePlus	ICGC;COSMIC	20.411	Down-regulation
CK1_CK1_CK1-A_CSNK1A1_ST	P18846	ATF1	P48729	CSNK1A1	S41	Q42K	42	Missense	proximal	1	no	23.501	23.057	EPSD;PhosphoSitePlus	ICGC;COSMIC	20.411	Down-regulation
CK1_CK1_CK1-A_CSNK1A1_ST	P18846	ATF1	P48729	CSNK1A1	S41	S44A	44	Missense	distal	3	no	23.501	21.271	EPSD;PhosphoSitePlus	ICGC;COSMIC	20.411	Down-regulation
CK1_CK1_CK1-A_CSNK1A1_ST	P18846	ATF1	P48729	CSNK1A1	S47	Q42K	42	Missense	distal	-5	no	27.155	25.970	PhosphoSitePlus;EPSD	ICGC;COSMIC	20.411	Down-regulation
CK1_CK1_CK1-A_CSNK1A1_ST	P18846	ATF1	P48729	CSNK1A1	S47	S44A	44	Missense	distal	-3	no	27.155	22.699	PhosphoSitePlus;EPSD	ICGC;COSMIC	20.411	Down-regulation
CK1_CK1_CK1-A_CSNK1A1_ST	P18846	ATF1	P48729	CSNK1A1	S50	S44A	44	Missense	distal	-6	no	24.340	23.432	EPSD;PhosphoSitePlus	ICGC;COSMIC	20.411	Down-regulation
CK1_CK1_CK1-A_CSNK1A1_ST	Q9Y4G8	RAPGEF2	P48729	CSNK1A1	S935	G937C	937	Missense	proximal	2	no	21.391	20.061	EPSD	ICGC;COSMIC	20.411	Loss
CK1_CK1_CK1-A_CSNK1A1_ST	Q9Y4G8	RAPGEF2	P48729	CSNK1A1	S935	S935I	935	Missense	central	0	yes	21.391	0.000	EPSD	ICGC	20.411	Loss
CK1_CK1_CK1-A_CSNK1A1_ST	Q9Y4G8	RAPGEF2	P48729	CSNK1A1	S935	S933Y	933	Missense	proximal	-2	no	21.391	19.349	EPSD	ICGC	20.411	Loss
CK1_CK1_CK1-A_CSNK1A1_ST	Q9Y4G8	RAPGEF2	P48729	CSNK1A1	S1095	L1090F	1090	Missense	distal	-5	no	21.168	19.896	EPSD	ICGC	20.411	Loss
CK1_CK1_CK1-A_CSNK1A1_ST	Q9Y4G8	RAPGEF2	P48729	CSNK1A1	S1108	S1112L	1112	Missense	distal	4	no	21.052	21.082	EPSD	ICGC;COSMIC	20.411	Up-regulation
CK1_CK1_CK1-A_CSNK1A1_ST	Q9Y4G8	RAPGEF2	P48729	CSNK1A1	S1108	E1104A	1104	Missense	distal	-4	no	21.052	18.894	EPSD	ICGC	20.411	Loss
CK1_CK1_CK1-A_CSNK1A1_ST	Q9Y4G8	RAPGEF2	P48729	CSNK1A1	S1153	V1155F	1155	Missense	proximal	2	no	22.514	22.765	EPSD	ICGC	20.411	Up-regulation
CK1_CK1_CK1-A_CSNK1A1_ST	Q9Y4G8	RAPGEF2	P48729	CSNK1A1	S1156	V1155F	1155	Missense	proximal	-1	no	21.524	21.555	EPSD	ICGC	20.411	Up-regulation
CK1_CK1_CK1-A_CSNK1A1_ST	Q9Y4G8	RAPGEF2	P48729	CSNK1A1	S1159	V1155F	1155	Missense	distal	-4	no	20.141	21.275	EPSD	ICGC	20.411	Gain
CK1_CK1_CK1-A_CSNK1A1_ST	Q9Y4G8	RAPGEF2	P48729	CSNK1A1	S1162	V1155F	1155	Missense	distal	-7	no	19.499	20.794	EPSD	ICGC	20.411	Gain
CK1_CK1_CK1-A_CSNK1A1_ST	Q9Y4G8	RAPGEF2	P48729	CSNK1A1	S1230	A1237T	1237	Missense	distal	7	no	23.223	23.204	EPSD	ICGC;COSMIC;GDSC;CCLE	20.411	Down-regulation
CK1_CK1_CK1-A_CSNK1A1_ST	Q9Y4G8	RAPGEF2	P48729	CSNK1A1	S1230	A1237V	1237	Missense	distal	7	no	23.223	23.342	EPSD	ICGC;COSMIC	20.411	Up-regulation
CK1_CK1_CK1-A_CSNK1A1_ST	Q9Y4G8	RAPGEF2	P48729	CSNK1A1	S1230	R1236L	1236	Missense	distal	6	no	23.223	23.276	EPSD	ICGC	20.411	Up-regulation
CK1_CK1_CK1-A_CSNK1A1_ST	Q9Y4G8	RAPGEF2	P48729	CSNK1A1	S1238	A1237T	1237	Missense	proximal	-1	no	21.897	21.631	EPSD	ICGC;COSMIC;GDSC;CCLE	20.411	Down-regulation
CK1_CK1_CK1-A_CSNK1A1_ST	Q9Y4G8	RAPGEF2	P48729	CSNK1A1	S1238	A1237V	1237	Missense	proximal	-1	no	21.897	21.295	EPSD	ICGC;COSMIC	20.411	Down-regulation
CK1_CK1_CK1-A_CSNK1A1_ST	Q9Y4G8	RAPGEF2	P48729	CSNK1A1	S1238	R1236L	1236	Missense	proximal	-2	no	21.897	20.134	EPSD	ICGC	20.411	Loss
CK1_CK1_CK1-A_CSNK1A1_ST	Q9Y4G8	RAPGEF2	P48729	CSNK1A1	S1238	A1242S	1242	Missense	distal	4	no	21.897	21.921	EPSD	ICGC;COSMIC	20.411	Up-regulation
CK1_CK1_CK1-A_CSNK1A1_ST	Q9Y4G8	RAPGEF2	P48729	CSNK1A1	S1244	A1237T	1237	Missense	distal	-7	no	24.769	23.797	EPSD;PhosphoSitePlus	ICGC;COSMIC;GDSC;CCLE	20.411	Down-regulation
CK1_CK1_CK1-A_CSNK1A1_ST	Q9Y4G8	RAPGEF2	P48729	CSNK1A1	S1244	A1237V	1237	Missense	distal	-7	no	24.769	22.534	EPSD;PhosphoSitePlus	ICGC;COSMIC	20.411	Down-regulation
CK1_CK1_CK1-A_CSNK1A1_ST	Q9Y4G8	RAPGEF2	P48729	CSNK1A1	S1244	A1242S	1242	Missense	proximal	-2	no	24.769	25.728	EPSD;PhosphoSitePlus	ICGC;COSMIC	20.411	Up-regulation
CK1_CK1_CK1-A_CSNK1A1_ST	Q9Y4G8	RAPGEF2	P48729	CSNK1A1	S1248	A1242S	1242	Missense	distal	-6	no	21.193	22.101	PhosphoSitePlus;EPSD	ICGC;COSMIC	20.411	Up-regulation
CK1_CK1_CK1-A_CSNK1A1_ST	Q9Y4G8	RAPGEF2	P48729	CSNK1A1	S1316	R1323L	1323	Missense	distal	7	no	27.746	27.675	EPSD	ICGC	20.411	Down-regulation
CK1_CK1_CK1-A_CSNK1A1_ST	Q9Y4G8	RAPGEF2	P48729	CSNK1A1	S1322	S1325I	1325	Missense	distal	3	no	21.479	20.223	EPSD	ICGC	20.411	Loss
CK1_CK1_CK1-A_CSNK1A1_ST	Q9Y4G8	RAPGEF2	P48729	CSNK1A1	S1322	R1323L	1323	Missense	proximal	1	no	21.479	21.795	EPSD	ICGC	20.411	Up-regulation
CK1_CK1_CK1-A_CSNK1A1_ST	Q9Y4G8	RAPGEF2	P48729	CSNK1A1	S1325	T1330K	1330	Missense	distal	5	no	23.302	23.502	EPSD	ICGC;COSMIC	20.411	Up-regulation
CK1_CK1_CK1-A_CSNK1A1_ST	Q9Y4G8	RAPGEF2	P48729	CSNK1A1	S1325	S1325I	1325	Missense	central	0	yes	23.302	0.000	EPSD	ICGC	20.411	Loss
CK1_CK1_CK1-A_CSNK1A1_ST	Q9Y4G8	RAPGEF2	P48729	CSNK1A1	S1325	R1323L	1323	Missense	proximal	-2	no	23.302	21.539	EPSD	ICGC	20.411	Down-regulation
CK1_CK1_CK1-A_CSNK1A1_ST	Q9Y4G8	RAPGEF2	P48729	CSNK1A1	S1328	T1330K	1330	Missense	proximal	2	no	20.464	20.230	EPSD	ICGC;COSMIC	20.411	Loss
CK1_CK1_CK1-A_CSNK1A1_ST	Q9Y4G8	RAPGEF2	P48729	CSNK1A1	S1328	S1325I	1325	Missense	distal	-3	no	20.464	16.482	EPSD	ICGC	20.411	Loss
CK1_CK1_CK1-A_CSNK1A1_ST	Q9Y4G8	RAPGEF2	P48729	CSNK1A1	S1328	R1323L	1323	Missense	distal	-5	no	20.464	20.706	EPSD	ICGC	20.411	Up-regulation
CK1_CK1_CK1-A_CSNK1A1_ST	Q9Y4G8	RAPGEF2	P48729	CSNK1A1	S1337	E1338K	1338	Missense	proximal	1	no	22.652	22.192	EPSD	ICGC;COSMIC	20.411	Down-regulation
CK1_CK1_CK1-A_CSNK1A1_ST	Q9Y4G8	RAPGEF2	P48729	CSNK1A1	S1337	T1330K	1330	Missense	distal	-7	no	22.652	23.884	EPSD	ICGC;COSMIC	20.411	Up-regulation
CK1_CK1_CK1-A_CSNK1A1_ST	P04637	TP53	P48729	CSNK1A1	S6	E11K	11	Missense	distal	5	no	22.651	23.096	EPSD	ICGC;COSMIC	20.411	Up-regulation
CK1_CK1_CK1-A_CSNK1A1_ST	P04637	TP53	P48729	CSNK1A1	S9	E11K	11	Missense	proximal	2	no	20.768	19.792	EPSD	ICGC;COSMIC	20.411	Loss
CK1_CK1_CK1-A_CSNK1A1_ST	P04637	TP53	P48729	CSNK1A1	S46	D48G	48	Missense	proximal	2	no	20.672	20.876	EPSD	ICGC;COSMIC	20.411	Up-regulation
CK1_CK1_CK1-A_CSNK1A1_ST	P04637	TP53	P48729	CSNK1A1	S46	Q52K	52	Missense	distal	6	no	20.672	20.564	EPSD	ICGC	20.411	Down-regulation
CK1_CK1_CK1-A_CSNK1A1_ST	P17931	LGALS3	P48729	CSNK1A1	S12	N18T	18	Missense	distal	6	no	22.212	22.325	EPSD;PhosphoSitePlus	ICGC;COSMIC	20.411	Up-regulation
CK1_CK1_CK1-A_CSNK1A1_ST	Q13009	TIAM1	P48729	CSNK1A1	S63	S59G	59	Missense	distal	-4	no	23.913	24.078	EPSD	ICGC;COSMIC	20.411	Up-regulation
CK1_CK1_CK1-A_CSNK1A1_ST	Q13009	TIAM1	P48729	CSNK1A1	S63	S67F	67	Missense	distal	4	no	23.913	23.826	EPSD	ICGC	20.411	Down-regulation
CK1_CK1_CK1-A_CSNK1A1_ST	Q13009	TIAM1	P48729	CSNK1A1	S219	G213E	213	Missense	distal	-6	no	20.495	19.684	EPSD	ICGC;COSMIC	20.411	Loss
CK1_CK1_CK1-A_CSNK1A1_ST	Q13009	TIAM1	P48729	CSNK1A1	S251	T244A	244	Missense	distal	-7	no	20.260	21.232	EPSD	ICGC;COSMIC	20.411	Gain
CK1_CK1_CK1-A_CSNK1A1_ST	Q13009	TIAM1	P48729	CSNK1A1	S334	T341N	341	Missense	distal	7	no	20.464	20.450	EPSD	ICGC;COSMIC	20.411	Down-regulation
CK1_CK1_CK1-A_CSNK1A1_ST	Q13009	TIAM1	P48729	CSNK1A1	S334	E327K	327	Missense	distal	-7	no	20.464	20.702	EPSD	ICGC;COSMIC	20.411	Up-regulation
CK1_CK1_CK1-A_CSNK1A1_ST	Q13009	TIAM1	P48729	CSNK1A1	S372	S370R	370	Missense	proximal	-2	no	20.561	19.471	EPSD	ICGC	20.411	Loss
CK1_CK1_CK1-A_CSNK1A1_ST	Q13009	TIAM1	P48729	CSNK1A1	S373	S370R	370	Missense	distal	-3	no	23.499	19.273	EPSD	ICGC	20.411	Loss
CK1_CK1_CK1-A_CSNK1A1_ST	Q13009	TIAM1	P48729	CSNK1A1	S374	S370R	370	Missense	distal	-4	no	23.810	21.777	EPSD	ICGC	20.411	Down-regulation
CK1_CK1_CK1-A_CSNK1A1_ST	Q13009	TIAM1	P48729	CSNK1A1	S483	Y477H	477	Missense	distal	-6	no	25.529	25.471	EPSD	ICGC;COSMIC	20.411	Down-regulation
CK1_CK1_CK1-A_CSNK1A1_ST	Q13009	TIAM1	P48729	CSNK1A1	S483	S489N	489	Missense	distal	6	no	25.529	25.312	EPSD	ICGC	20.411	Down-regulation
CK1_CK1_CK1-A_CSNK1A1_ST	Q13009	TIAM1	P48729	CSNK1A1	S726	A722T	722	Missense	distal	-4	no	21.784	21.749	EPSD	ICGC;COSMIC	20.411	Down-regulation
CK1_CK1_CK1-A_CSNK1A1_ST	Q13009	TIAM1	P48729	CSNK1A1	S726	S726F	726	Missense	central	0	yes	21.784	0.000	EPSD	ICGC;COSMIC	20.411	Loss
CK1_CK1_CK1-A_CSNK1A1_ST	Q13009	TIAM1	P48729	CSNK1A1	S726	G719E	719	Missense	distal	-7	no	21.784	21.277	EPSD	ICGC	20.411	Down-regulation
CK1_CK1_CK1-A_CSNK1A1_ST	Q13009	TIAM1	P48729	CSNK1A1	S726	D732N	732	Missense	distal	6	no	21.784	21.638	EPSD	ICGC	20.411	Down-regulation
CK1_CK1_CK1-A_CSNK1A1_ST	Q13009	TIAM1	P48729	CSNK1A1	S989	E987K	987	Missense	proximal	-2	no	20.497	19.184	EPSD	ICGC;COSMIC	20.411	Loss
CK1_CK1_CK1-A_CSNK1A1_ST	Q13009	TIAM1	P48729	CSNK1A1	T992	E987K	987	Missense	distal	-5	no	21.646	21.028	EPSD	ICGC;COSMIC	20.411	Down-regulation
CK1_CK1_CK1-A_CSNK1A1_ST	Q13009	TIAM1	P48729	CSNK1A1	S1020	G1026E	1026	Missense	distal	6	no	23.833	23.519	EPSD	ICGC;COSMIC;GDSC;CCLE	20.411	Down-regulation
CK1_CK1_CK1-A_CSNK1A1_ST	Q12968	NFATC3	P48729	CSNK1A1	S168	S169N	169	Missense	proximal	1	no	22.546	22.490	EPSD	ICGC;COSMIC	20.411	Down-regulation
CK1_CK1_CK1-A_CSNK1A1_ST	Q12968	NFATC3	P48729	CSNK1A1	S236	H233D	233	Missense	distal	-3	no	14.913	21.151	EPSD	ICGC;COSMIC	20.411	Gain
CK1_CK1_CK1-A_CSNK1A1_ST	Q12968	NFATC3	P48729	CSNK1A1	S269	P270L	270	Missense	proximal	1	no	20.697	20.807	EPSD	ICGC;COSMIC	20.411	Up-regulation
CK1_CK1_CK1-A_CSNK1A1_ST	Q12968	NFATC3	P48729	CSNK1A1	S269	R274W	274	Missense	distal	5	no	20.697	20.970	EPSD	ICGC;COSMIC	20.411	Up-regulation
CK1_CK1_CK1-A_CSNK1A1_ST	Q12968	NFATC3	P48729	CSNK1A1	S372	R369W	369	Missense	distal	-3	no	18.604	21.874	EPSD	ICGC;COSMIC;GDSC	20.411	Gain
CK1_CK1_CK1-A_CSNK1A1_ST	Q12968	NFATC3	P48729	CSNK1A1	S742	S746I	746	Missense	distal	4	no	21.943	21.964	EPSD	ICGC	20.411	Up-regulation
CK1_CK1_CK1-A_CSNK1A1_ST	Q12968	NFATC3	P48729	CSNK1A1	S1048	V1049F	1049	Missense	proximal	1	no	23.341	23.298	EPSD	ICGC	20.411	Down-regulation
CK1_CK1_CK1-A_CSNK1A1_ST	Q12968	NFATC3	P48729	CSNK1A1	S1048	G1041W	1041	Missense	distal	-7	no	23.341	20.654	EPSD	ICGC;COSMIC	20.411	Down-regulation
CK1_CK1_CK1-A_CSNK1A1_ST	Q12968	NFATC3	P48729	CSNK1A1	S1048	G1041V	1041	Missense	distal	-7	no	23.341	20.576	EPSD	ICGC;COSMIC	20.411	Down-regulation
CK1_CK1_CK1-A_CSNK1A1_ST	O60716	CTNND1	P48729	CSNK1A1	T134	S129I	129	Missense	distal	-5	no	21.402	21.230	EPSD	ICGC	20.411	Down-regulation
CK1_CK1_CK1-A_CSNK1A1_ST	O60716	CTNND1	P48729	CSNK1A1	T134	R135H	135	Missense	proximal	1	no	21.402	21.316	EPSD	ICGC;COSMIC	20.411	Down-regulation
CK1_CK1_CK1-A_CSNK1A1_ST	O60716	CTNND1	P48729	CSNK1A1	T134	R135S	135	Missense	proximal	1	no	21.402	21.456	EPSD	ICGC;COSMIC	20.411	Up-regulation
CK1_CK1_CK1-A_CSNK1A1_ST	O60716	CTNND1	P48729	CSNK1A1	S252	R253H	253	Missense	proximal	1	no	20.799	20.713	EPSD	ICGC;COSMIC	20.411	Down-regulation
CK1_CK1_CK1-A_CSNK1A1_ST	P56817	BACE1	P48729	CSNK1A1	S59	R57S	57	Missense	proximal	-2	no	22.859	23.949	EPSD	ICGC;COSMIC	20.411	Up-regulation
CK1_CK1_CK1-A_CSNK1A1_ST	P56817	BACE1	P48729	CSNK1A1	S59	D65E	65	Missense	distal	6	no	22.859	22.633	EPSD	ICGC	20.411	Down-regulation
CK1_CK1_CK1-A_CSNK1A1_ST	P56817	BACE1	P48729	CSNK1A1	S59	V61M	61	Missense	proximal	2	no	22.859	23.305	EPSD	ICGC;COSMIC	20.411	Up-regulation
CK1_CK1_CK1-A_CSNK1A1_ST	P56817	BACE1	P48729	CSNK1A1	S59	R57H	57	Missense	proximal	-2	no	22.859	21.238	EPSD	ICGC	20.411	Down-regulation
CK1_CK1_CK1-A_CSNK1A1_ST	Q9NRF8	CTPS2	P48729	CSNK1A1	S568	S562P	562	Missense	distal	-6	no	20.414	19.733	PhosphoSitePlus	ICGC;COSMIC	20.411	Loss
CK1_CK1_CK1-A_CSNK1A1_ST	Q9NRF8	CTPS2	P48729	CSNK1A1	S568	D565N	565	Missense	distal	-3	no	20.414	15.134	PhosphoSitePlus	ICGC	20.411	Loss
CK1_CK1_CK1-A_CSNK1A1_ST	P51532	SMARCA4	P48729	CSNK1A1	S38	S31N	31	Missense	distal	-7	no	24.806	25.010	EPSD	ICGC;COSMIC	20.411	Up-regulation
CK1_CK1_CK1-A_CSNK1A1_ST	P51532	SMARCA4	P48729	CSNK1A1	S38	S38P	38	Missense	central	0	yes	24.806	0.000	EPSD	ICGC;COSMIC	20.411	Loss
CK1_CK1_CK1-A_CSNK1A1_ST	P51532	SMARCA4	P48729	CSNK1A1	S38	S41G	41	Missense	distal	3	no	24.806	25.254	EPSD	ICGC;COSMIC	20.411	Up-regulation
CK1_CK1_CK1-A_CSNK1A1_ST	P51532	SMARCA4	P48729	CSNK1A1	S38	G33V	33	Missense	distal	-5	no	24.806	22.753	EPSD	ICGC	20.411	Down-regulation
CK1_CK1_CK1-A_CSNK1A1_ST	P51532	SMARCA4	P48729	CSNK1A1	S111	S111N	111	Missense	central	0	yes	20.572	0.000	EPSD	ICGC	20.411	Loss
CK1_CK1_CK1-A_CSNK1A1_ST	P51532	SMARCA4	P48729	CSNK1A1	S111	G107K	107	Missense	distal	-4	no	20.572	17.268	EPSD	ICGC	20.411	Loss
CK1_CK1_CK1-A_CSNK1A1_ST	P51532	SMARCA4	P48729	CSNK1A1	S111	M113I	113	Missense	proximal	2	no	20.572	20.601	EPSD	ICGC;COSMIC	20.411	Up-regulation
CK1_CK1_CK1-A_CSNK1A1_ST	P51532	SMARCA4	P48729	CSNK1A1	S111	H116Y	116	Missense	distal	5	no	20.572	20.526	EPSD	ICGC;COSMIC	20.411	Down-regulation
CK1_CK1_CK1-A_CSNK1A1_ST	P51532	SMARCA4	P48729	CSNK1A1	S147	A152S	152	Missense	distal	5	no	21.551	21.233	EPSD	ICGC;COSMIC	20.411	Down-regulation
CK1_CK1_CK1-A_CSNK1A1_ST	P51532	SMARCA4	P48729	CSNK1A1	S147	P153Q	153	Missense	distal	6	no	21.551	21.500	EPSD	ICGC;COSMIC	20.411	Down-regulation
CK1_CK1_CK1-A_CSNK1A1_ST	P51532	SMARCA4	P48729	CSNK1A1	S147	G142V	142	Missense	distal	-5	no	21.551	19.498	EPSD	ICGC;COSMIC	20.411	Loss
CK1_CK1_CK1-A_CSNK1A1_ST	P51532	SMARCA4	P48729	CSNK1A1	S660	G661D	661	Missense	proximal	1	no	27.117	27.071	EPSD	ICGC	20.411	Down-regulation
CK1_CK1_CK1-A_CSNK1A1_ST	P51532	SMARCA4	P48729	CSNK1A1	S662	G661D	661	Missense	proximal	-1	no	21.031	20.758	EPSD	ICGC	20.411	Down-regulation
CK1_CK1_CK1-A_CSNK1A1_ST	P51532	SMARCA4	P48729	CSNK1A1	S662	E669D	669	Missense	distal	7	no	21.031	21.117	EPSD	ICGC;COSMIC	20.411	Up-regulation
CK1_CK1_CK1-A_CSNK1A1_ST	P51532	SMARCA4	P48729	CSNK1A1	S695	P693L	693	Missense	proximal	-2	no	20.891	19.907	EPSD	ICGC	20.411	Loss
CK1_CK1_CK1-A_CSNK1A1_ST	P51532	SMARCA4	P48729	CSNK1A1	S699	R704W	704	Missense	distal	5	no	25.806	26.079	EPSD	ICGC;COSMIC	20.411	Up-regulation
CK1_CK1_CK1-A_CSNK1A1_ST	P51532	SMARCA4	P48729	CSNK1A1	S699	P693L	693	Missense	distal	-6	no	25.806	25.593	EPSD	ICGC	20.411	Down-regulation
CK1_CK1_CK1-A_CSNK1A1_ST	P51532	SMARCA4	P48729	CSNK1A1	S746	V753F	753	Missense	distal	7	no	21.090	21.079	EPSD	ICGC	20.411	Down-regulation
CK1_CK1_CK1-A_CSNK1A1_ST	P51532	SMARCA4	P48729	CSNK1A1	S746	A747S	747	Missense	proximal	1	no	21.090	21.126	EPSD	ICGC;COSMIC	20.411	Up-regulation
CK1_CK1_CK1-A_CSNK1A1_ST	P51532	SMARCA4	P48729	CSNK1A1	S746	L748P	748	Missense	proximal	2	no	21.090	21.060	EPSD	ICGC;COSMIC	20.411	Down-regulation
CK1_CK1_CK1-A_CSNK1A1_ST	P51532	SMARCA4	P48729	CSNK1A1	S1238	R1243Q	1243	Missense	distal	5	no	22.517	21.983	EPSD	ICGC;COSMIC	20.411	Down-regulation
CK1_CK1_CK1-A_CSNK1A1_ST	P51532	SMARCA4	P48729	CSNK1A1	S1238	M1233T	1233	Missense	distal	-5	no	22.517	21.300	EPSD	ICGC	20.411	Down-regulation
CK1_CK1_CK1-A_CSNK1A1_ST	P51532	SMARCA4	P48729	CSNK1A1	S1238	K1237E	1237	Missense	proximal	-1	no	22.517	24.158	EPSD	ICGC;COSMIC	20.411	Up-regulation
CK1_CK1_CK1-A_CSNK1A1_ST	P51532	SMARCA4	P48729	CSNK1A1	S1238	S1239P	1239	Missense	proximal	1	no	22.517	22.669	EPSD	ICGC;COSMIC	20.411	Up-regulation
CK1_CK1_CK1-A_CSNK1A1_ST	P51532	SMARCA4	P48729	CSNK1A1	S1238	H1241Q	1241	Missense	distal	3	no	22.517	24.354	EPSD	ICGC;COSMIC	20.411	Up-regulation
CK1_CK1_CK1-A_CSNK1A1_ST	P51532	SMARCA4	P48729	CSNK1A1	S1239	R1243Q	1243	Missense	distal	4	no	21.136	21.038	EPSD	ICGC;COSMIC	20.411	Down-regulation
CK1_CK1_CK1-A_CSNK1A1_ST	P51532	SMARCA4	P48729	CSNK1A1	S1239	M1233T	1233	Missense	distal	-6	no	21.136	20.893	EPSD	ICGC	20.411	Down-regulation
CK1_CK1_CK1-A_CSNK1A1_ST	P51532	SMARCA4	P48729	CSNK1A1	S1239	K1237E	1237	Missense	proximal	-2	no	21.136	22.449	EPSD	ICGC;COSMIC	20.411	Up-regulation
CK1_CK1_CK1-A_CSNK1A1_ST	P51532	SMARCA4	P48729	CSNK1A1	S1239	S1239P	1239	Missense	central	0	yes	21.136	0.000	EPSD	ICGC;COSMIC	20.411	Loss
CK1_CK1_CK1-A_CSNK1A1_ST	P51532	SMARCA4	P48729	CSNK1A1	S1239	H1241Q	1241	Missense	proximal	2	no	21.136	22.153	EPSD	ICGC;COSMIC	20.411	Up-regulation
CK1_CK1_CK1-A_CSNK1A1_ST	P51532	SMARCA4	P48729	CSNK1A1	S1640	S1644N	1644	Missense	distal	4	no	21.137	21.058	EPSD	ICGC	20.411	Down-regulation
CK1_CK1_CK1-A_CSNK1A1_ST	P51532	SMARCA4	P48729	CSNK1A1	S1644	S1644N	1644	Missense	central	0	yes	20.946	0.000	EPSD	ICGC	20.411	Loss
CK1_CK1_CK1-A_CSNK1A1_ST	P16220	CREB1	P48729	CSNK1A1	S156	E153G	153	Missense	distal	-3	no	22.985	23.398	EPSD;PhosphoSitePlus	ICGC	20.411	Up-regulation
CK1_CK1_CK1-A_CSNK1A1_ST	P25054	APC	P48729	CSNK1A1	S92	V85I	85	Missense	distal	-7	no	19.937	21.989	EPSD	ICGC;COSMIC	20.411	Gain
CK1_CK1_CK1-A_CSNK1A1_ST	P25054	APC	P48729	CSNK1A1	S95	L93I	93	Missense	proximal	-2	no	20.190	20.864	EPSD	ICGC;COSMIC	20.411	Gain
CK1_CK1_CK1-A_CSNK1A1_ST	P25054	APC	P48729	CSNK1A1	S98	S92C	92	Missense	distal	-6	no	23.082	22.229	EPSD	ICGC;COSMIC	20.411	Down-regulation
CK1_CK1_CK1-A_CSNK1A1_ST	P25054	APC	P48729	CSNK1A1	S98	L93I	93	Missense	distal	-5	no	23.082	23.539	EPSD	ICGC;COSMIC	20.411	Up-regulation
CK1_CK1_CK1-A_CSNK1A1_ST	P25054	APC	P48729	CSNK1A1	S130	T131A	131	Missense	proximal	1	no	23.805	23.760	EPSD	ICGC;COSMIC	20.411	Down-regulation
CK1_CK1_CK1-A_CSNK1A1_ST	P25054	APC	P48729	CSNK1A1	S130	V124A	124	Missense	distal	-6	no	23.805	24.063	EPSD	ICGC	20.411	Up-regulation
CK1_CK1_CK1-A_CSNK1A1_ST	P25054	APC	P48729	CSNK1A1	S293	S294Y	294	Missense	proximal	1	no	23.718	23.649	EPSD	ICGC;COSMIC	20.411	Down-regulation
CK1_CK1_CK1-A_CSNK1A1_ST	P25054	APC	P48729	CSNK1A1	S293	S293I	293	Missense	central	0	yes	23.718	0.000	EPSD	ICGC	20.411	Loss
CK1_CK1_CK1-A_CSNK1A1_ST	P25054	APC	P48729	CSNK1A1	S843	S846Y	846	Missense	distal	3	no	21.386	18.581	EPSD	ICGC;COSMIC	20.411	Loss
CK1_CK1_CK1-A_CSNK1A1_ST	P25054	APC	P48729	CSNK1A1	S843	S843R	843	Missense	central	0	yes	21.386	0.000	EPSD	ICGC;COSMIC	20.411	Loss
CK1_CK1_CK1-A_CSNK1A1_ST	P25054	APC	P48729	CSNK1A1	S843	R845H	845	Missense	proximal	2	no	21.386	20.660	EPSD	ICGC;COSMIC	20.411	Down-regulation
CK1_CK1_CK1-A_CSNK1A1_ST	P25054	APC	P48729	CSNK1A1	S843	R838S	838	Missense	distal	-5	no	21.386	22.257	EPSD	ICGC;COSMIC	20.411	Up-regulation
CK1_CK1_CK1-A_CSNK1A1_ST	P25054	APC	P48729	CSNK1A1	S846	S846Y	846	Missense	central	0	yes	27.884	0.000	EPSD	ICGC;COSMIC	20.411	Loss
CK1_CK1_CK1-A_CSNK1A1_ST	P25054	APC	P48729	CSNK1A1	S846	S843R	843	Missense	distal	-3	no	27.884	23.658	EPSD	ICGC;COSMIC	20.411	Down-regulation
CK1_CK1_CK1-A_CSNK1A1_ST	P25054	APC	P48729	CSNK1A1	S846	R845H	845	Missense	proximal	-1	no	27.884	27.203	EPSD	ICGC;COSMIC	20.411	Down-regulation
CK1_CK1_CK1-A_CSNK1A1_ST	P25054	APC	P48729	CSNK1A1	S905	S900Y	900	Missense	distal	-5	no	23.470	21.524	EPSD	ICGC;COSMIC	20.411	Down-regulation
CK1_CK1_CK1-A_CSNK1A1_ST	P25054	APC	P48729	CSNK1A1	S905	T910N	910	Missense	distal	5	no	23.470	23.680	EPSD	ICGC;COSMIC	20.411	Up-regulation
CK1_CK1_CK1-A_CSNK1A1_ST	P25054	APC	P48729	CSNK1A1	S905	S908Y	908	Missense	distal	3	no	23.470	20.665	EPSD	ICGC;COSMIC	20.411	Down-regulation
CK1_CK1_CK1-A_CSNK1A1_ST	P25054	APC	P48729	CSNK1A1	S906	S900Y	900	Missense	distal	-6	no	21.922	20.874	EPSD	ICGC;COSMIC	20.411	Down-regulation
CK1_CK1_CK1-A_CSNK1A1_ST	P25054	APC	P48729	CSNK1A1	S906	T910N	910	Missense	distal	4	no	21.922	21.878	EPSD	ICGC;COSMIC	20.411	Down-regulation
CK1_CK1_CK1-A_CSNK1A1_ST	P25054	APC	P48729	CSNK1A1	S906	S908Y	908	Missense	proximal	2	no	21.922	20.597	EPSD	ICGC;COSMIC	20.411	Down-regulation
CK1_CK1_CK1-A_CSNK1A1_ST	P25054	APC	P48729	CSNK1A1	S908	T910N	910	Missense	proximal	2	no	21.006	20.747	EPSD	ICGC;COSMIC	20.411	Down-regulation
CK1_CK1_CK1-A_CSNK1A1_ST	P25054	APC	P48729	CSNK1A1	S908	S908Y	908	Missense	central	0	yes	21.006	0.000	EPSD	ICGC;COSMIC	20.411	Loss
CK1_CK1_CK1-A_CSNK1A1_ST	P25054	APC	P48729	CSNK1A1	S966	S969I	969	Missense	distal	3	no	21.829	20.573	EPSD	ICGC;COSMIC	20.411	Down-regulation
CK1_CK1_CK1-A_CSNK1A1_ST	P25054	APC	P48729	CSNK1A1	S966	S959P	959	Missense	distal	-7	no	21.829	21.163	EPSD	ICGC;COSMIC	20.411	Down-regulation
CK1_CK1_CK1-A_CSNK1A1_ST	P25054	APC	P48729	CSNK1A1	S982	Y986S	986	Missense	distal	4	no	22.598	22.741	EPSD	ICGC	20.411	Up-regulation
CK1_CK1_CK1-A_CSNK1A1_ST	P25054	APC	P48729	CSNK1A1	S985	Y986S	986	Missense	proximal	1	no	20.558	20.627	EPSD	ICGC	20.411	Up-regulation
CK1_CK1_CK1-A_CSNK1A1_ST	P25054	APC	P48729	CSNK1A1	S987	Y986S	986	Missense	proximal	-1	no	22.463	23.349	EPSD	ICGC	20.411	Up-regulation
CK1_CK1_CK1-A_CSNK1A1_ST	P25054	APC	P48729	CSNK1A1	S992	S996I	996	Missense	distal	4	no	22.129	22.150	EPSD	ICGC;COSMIC	20.411	Up-regulation
CK1_CK1_CK1-A_CSNK1A1_ST	P25054	APC	P48729	CSNK1A1	S992	Y986S	986	Missense	distal	-6	no	22.129	23.177	EPSD	ICGC	20.411	Up-regulation
CK1_CK1_CK1-A_CSNK1A1_ST	P25054	APC	P48729	CSNK1A1	S1044	R1040S	1040	Missense	distal	-4	no	20.281	22.314	EPSD	ICGC;COSMIC	20.411	Gain
CK1_CK1_CK1-A_CSNK1A1_ST	P25054	APC	P48729	CSNK1A1	S1044	R1040T	1040	Missense	distal	-4	no	20.281	20.679	EPSD	ICGC;COSMIC	20.411	Gain
CK1_CK1_CK1-A_CSNK1A1_ST	P25054	APC	P48729	CSNK1A1	S1044	Q1041E	1041	Missense	distal	-3	no	20.281	21.447	EPSD	ICGC;COSMIC	20.411	Gain
CK1_CK1_CK1-A_CSNK1A1_ST	P25054	APC	P48729	CSNK1A1	S1148	E1151Q	1151	Missense	distal	3	no	22.107	19.536	EPSD	ICGC;COSMIC	20.411	Loss
CK1_CK1_CK1-A_CSNK1A1_ST	P25054	APC	P48729	CSNK1A1	S1148	S1148Y	1148	Missense	central	0	yes	22.107	0.000	EPSD	ICGC;COSMIC	20.411	Loss
CK1_CK1_CK1-A_CSNK1A1_ST	P25054	APC	P48729	CSNK1A1	S1279	R1273I	1273	Missense	distal	-6	no	22.356	21.878	EPSD	ICGC	20.411	Down-regulation
CK1_CK1_CK1-A_CSNK1A1_ST	P25054	APC	P48729	CSNK1A1	S1343	S1346L	1346	Missense	distal	3	no	20.865	17.113	EPSD	ICGC;COSMIC	20.411	Loss
CK1_CK1_CK1-A_CSNK1A1_ST	P25054	APC	P48729	CSNK1A1	S1343	A1347T	1347	Missense	distal	4	no	20.865	20.854	EPSD	ICGC;COSMIC	20.411	Down-regulation
CK1_CK1_CK1-A_CSNK1A1_ST	P25054	APC	P48729	CSNK1A1	S1392	R1399S	1399	Missense	distal	7	no	21.764	21.657	EPSD	ICGC;COSMIC	20.411	Down-regulation
CK1_CK1_CK1-A_CSNK1A1_ST	P25054	APC	P48729	CSNK1A1	S1392	R1386I	1386	Missense	distal	-6	no	21.764	21.285	EPSD	ICGC	20.411	Down-regulation
CK1_CK1_CK1-A_CSNK1A1_ST	P25054	APC	P48729	CSNK1A1	S1392	T1388A	1388	Missense	distal	-4	no	21.764	21.798	EPSD	ICGC;COSMIC	20.411	Up-regulation
CK1_CK1_CK1-A_CSNK1A1_ST	P25054	APC	P48729	CSNK1A1	S1392	R1399C	1399	Missense	distal	7	no	21.764	21.809	EPSD	ICGC;COSMIC;CCLE	20.411	Up-regulation
CK1_CK1_CK1-A_CSNK1A1_ST	P25054	APC	P48729	CSNK1A1	S1395	R1399S	1399	Missense	distal	4	no	21.416	21.387	EPSD	ICGC;COSMIC	20.411	Down-regulation
CK1_CK1_CK1-A_CSNK1A1_ST	P25054	APC	P48729	CSNK1A1	S1395	T1388A	1388	Missense	distal	-7	no	21.416	22.388	EPSD	ICGC;COSMIC	20.411	Up-regulation
CK1_CK1_CK1-A_CSNK1A1_ST	P25054	APC	P48729	CSNK1A1	S1395	R1399C	1399	Missense	distal	4	no	21.416	21.267	EPSD	ICGC;COSMIC;CCLE	20.411	Down-regulation
CK1_CK1_CK1-A_CSNK1A1_ST	P25054	APC	P48729	CSNK1A1	S1395	A1402V	1402	Missense	distal	7	no	21.416	21.535	EPSD	ICGC;COSMIC	20.411	Up-regulation
CK1_CK1_CK1-A_CSNK1A1_ST	P25054	APC	P48729	CSNK1A1	S1395	A1402T	1402	Missense	distal	7	no	21.416	21.396	EPSD	ICGC;COSMIC	20.411	Down-regulation
CK1_CK1_CK1-A_CSNK1A1_ST	P25054	APC	P48729	CSNK1A1	S1398	R1399S	1399	Missense	proximal	1	no	25.131	25.185	EPSD	ICGC;COSMIC	20.411	Up-regulation
CK1_CK1_CK1-A_CSNK1A1_ST	P25054	APC	P48729	CSNK1A1	S1398	R1399C	1399	Missense	proximal	1	no	25.131	24.980	EPSD	ICGC;COSMIC;CCLE	20.411	Down-regulation
CK1_CK1_CK1-A_CSNK1A1_ST	P25054	APC	P48729	CSNK1A1	S1398	A1402V	1402	Missense	distal	4	no	25.131	25.060	EPSD	ICGC;COSMIC	20.411	Down-regulation
CK1_CK1_CK1-A_CSNK1A1_ST	P25054	APC	P48729	CSNK1A1	S1398	A1402T	1402	Missense	distal	4	no	25.131	25.120	EPSD	ICGC;COSMIC	20.411	Down-regulation
CK1_CK1_CK1-A_CSNK1A1_ST	P25054	APC	P48729	CSNK1A1	S1507	E1513D	1513	Missense	distal	6	no	26.279	26.505	PhosphoSitePlus;EPSD	ICGC	20.411	Up-regulation
CK1_CK1_CK1-A_CSNK1A1_ST	P25054	APC	P48729	CSNK1A1	S1510	E1513D	1513	Missense	distal	3	no	23.496	23.635	EPSD;PhosphoSitePlus	ICGC	20.411	Up-regulation
CK1_CK1_CK1-A_CSNK1A1_ST	P25054	APC	P48729	CSNK1A1	S1864	D1871V	1871	Missense	distal	7	no	20.267	20.503	EPSD	ICGC;COSMIC	20.411	Gain
CK1_CK1_CK1-A_CSNK1A1_ST	P25054	APC	P48729	CSNK1A1	S2034	Q2040P	2040	Missense	distal	6	no	22.264	22.314	EPSD	ICGC;COSMIC	20.411	Up-regulation
CK1_CK1_CK1-A_CSNK1A1_ST	P25054	APC	P48729	CSNK1A1	S2034	S2028I	2028	Missense	distal	-6	no	22.264	21.257	EPSD	ICGC	20.411	Down-regulation
CK1_CK1_CK1-A_CSNK1A1_ST	P25054	APC	P48729	CSNK1A1	S2034	S2031I	2031	Missense	distal	-3	no	22.264	18.282	EPSD	ICGC;COSMIC	20.411	Loss
CK1_CK1_CK1-A_CSNK1A1_ST	P25054	APC	P48729	CSNK1A1	S2137	L2144M	2144	Missense	distal	7	no	22.652	22.672	EPSD	ICGC;COSMIC	20.411	Up-regulation
CK1_CK1_CK1-A_CSNK1A1_ST	P25054	APC	P48729	CSNK1A1	S2143	G2145R	2145	Missense	proximal	2	no	21.084	20.132	EPSD	ICGC;COSMIC	20.411	Loss
CK1_CK1_CK1-A_CSNK1A1_ST	P25054	APC	P48729	CSNK1A1	S2143	L2144M	2144	Missense	proximal	1	no	21.084	20.764	EPSD	ICGC;COSMIC	20.411	Down-regulation
CK1_CK1_CK1-A_CSNK1A1_ST	P25054	APC	P48729	CSNK1A1	S2307	R2305T	2305	Missense	proximal	-2	no	23.911	23.868	EPSD	ICGC;COSMIC	20.411	Down-regulation
CK1_CK1_CK1-A_CSNK1A1_ST	P25054	APC	P48729	CSNK1A1	S2307	R2311I	2311	Missense	distal	4	no	23.911	23.903	EPSD	ICGC;COSMIC	20.411	Down-regulation
CK1_CK1_CK1-A_CSNK1A1_ST	P25054	APC	P48729	CSNK1A1	S2310	R2305T	2305	Missense	distal	-5	no	22.245	22.485	EPSD	ICGC;COSMIC	20.411	Up-regulation
CK1_CK1_CK1-A_CSNK1A1_ST	P25054	APC	P48729	CSNK1A1	S2310	R2311I	2311	Missense	proximal	1	no	22.245	22.472	EPSD	ICGC;COSMIC	20.411	Up-regulation
CK1_CK1_CK1-A_CSNK1A1_ST	P25054	APC	P48729	CSNK1A1	S2359	K2357T	2357	Missense	proximal	-2	no	20.329	20.511	EPSD	ICGC;COSMIC	20.411	Gain
CK1_CK1_CK1-A_CSNK1A1_ST	P25054	APC	P48729	CSNK1A1	S2424	R2431K	2431	Missense	distal	7	no	22.868	22.765	EPSD	ICGC;COSMIC	20.411	Down-regulation
CK1_CK1_CK1-A_CSNK1A1_ST	P25054	APC	P48729	CSNK1A1	S2425	S2432L	2432	Missense	distal	7	no	20.707	20.742	EPSD	ICGC;COSMIC	20.411	Up-regulation
CK1_CK1_CK1-A_CSNK1A1_ST	P25054	APC	P48729	CSNK1A1	S2425	R2431K	2431	Missense	distal	6	no	20.707	20.516	EPSD	ICGC;COSMIC	20.411	Down-regulation
CK1_CK1_CK1-A_CSNK1A1_ST	P25054	APC	P48729	CSNK1A1	S2427	S2432L	2432	Missense	distal	5	no	22.212	22.524	EPSD	ICGC;COSMIC	20.411	Up-regulation
CK1_CK1_CK1-A_CSNK1A1_ST	P25054	APC	P48729	CSNK1A1	S2427	R2431K	2431	Missense	distal	4	no	22.212	22.099	EPSD	ICGC;COSMIC	20.411	Down-regulation
CK1_CK1_CK1-A_CSNK1A1_ST	P25054	APC	P48729	CSNK1A1	S2429	S2432L	2432	Missense	distal	3	no	21.026	17.274	EPSD	ICGC;COSMIC	20.411	Loss
CK1_CK1_CK1-A_CSNK1A1_ST	P25054	APC	P48729	CSNK1A1	S2429	R2431K	2431	Missense	proximal	2	no	21.026	20.607	EPSD	ICGC;COSMIC	20.411	Down-regulation
CK1_CK1_CK1-A_CSNK1A1_ST	P25054	APC	P48729	CSNK1A1	S2461	S2464C	2464	Missense	distal	3	no	20.924	16.881	EPSD	ICGC;COSMIC	20.411	Loss
CK1_CK1_CK1-A_CSNK1A1_ST	P25054	APC	P48729	CSNK1A1	S2461	S2459F	2459	Missense	proximal	-2	no	20.924	19.057	EPSD	ICGC	20.411	Loss
CK1_CK1_CK1-A_CSNK1A1_ST	P25054	APC	P48729	CSNK1A1	S2466	S2464C	2464	Missense	proximal	-2	no	21.188	19.870	EPSD	ICGC;COSMIC	20.411	Loss
CK1_CK1_CK1-A_CSNK1A1_ST	P25054	APC	P48729	CSNK1A1	S2466	R2470I	2470	Missense	distal	4	no	21.188	21.180	EPSD	ICGC	20.411	Down-regulation
CK1_CK1_CK1-A_CSNK1A1_ST	P25054	APC	P48729	CSNK1A1	S2466	S2469F	2469	Missense	distal	3	no	21.188	18.727	EPSD	ICGC;COSMIC	20.411	Loss
CK1_CK1_CK1-A_CSNK1A1_ST	P25054	APC	P48729	CSNK1A1	S2466	S2459F	2459	Missense	distal	-7	no	21.188	20.770	EPSD	ICGC	20.411	Down-regulation
CK1_CK1_CK1-A_CSNK1A1_ST	P25054	APC	P48729	CSNK1A1	S2531	R2525H	2525	Missense	distal	-6	no	22.353	21.775	EPSD	ICGC	20.411	Down-regulation
CK1_CK1_CK1-A_CSNK1A1_ST	P25054	APC	P48729	CSNK1A1	S2572	R2566K	2566	Missense	distal	-6	no	22.288	21.868	EPSD	ICGC	20.411	Down-regulation
CK1_CK1_CK1-A_CSNK1A1_ST	P25054	APC	P48729	CSNK1A1	S2575	S2581R	2581	Missense	distal	6	no	24.897	24.704	EPSD	ICGC;COSMIC	20.411	Down-regulation
CK1_CK1_CK1-A_CSNK1A1_ST	P25054	APC	P48729	CSNK1A1	S2580	S2581R	2581	Missense	proximal	1	no	21.313	21.259	EPSD	ICGC;COSMIC	20.411	Down-regulation
CK1_CK1_CK1-A_CSNK1A1_ST	P25054	APC	P48729	CSNK1A1	T2635	V2630I	2630	Missense	distal	-5	no	19.071	20.658	EPSD	ICGC;COSMIC	20.411	Gain
CK1_CK1_CK1-A_CSNK1A1_ST	P25054	APC	P48729	CSNK1A1	S2674	G2672E	2672	Missense	proximal	-2	no	20.899	21.046	EPSD	ICGC	20.411	Up-regulation
CK1_CK1_CK1-A_CSNK1A1_ST	P08238	HSP90AB1	P48729	CSNK1A1	T166	R168C	168	Missense	proximal	2	no	20.706	20.328	EPSD	ICGC;COSMIC	20.411	Loss
CK1_CK1_CK1-A_CSNK1A1_ST	P08238	HSP90AB1	P48729	CSNK1A1	S255	D252Y	252	Missense	distal	-3	no	23.176	16.830	EPSD	ICGC	20.411	Loss
CK1_CK1_CK1-A_CSNK1A1_ST	P08238	HSP90AB1	P48729	CSNK1A1	S255	G262S	262	Missense	distal	7	no	23.176	23.155	EPSD	ICGC;COSMIC	20.411	Down-regulation
CK1_CK1_CK1-A_CSNK1A1_ST	P08238	HSP90AB1	P48729	CSNK1A1	S261	G262S	262	Missense	proximal	1	no	22.901	22.681	EPSD	ICGC;COSMIC	20.411	Down-regulation
CK1_CK1_CK1-A_CSNK1A1_ST	P08238	HSP90AB1	P48729	CSNK1A1	T297	P293A	293	Missense	distal	-4	no	20.976	22.068	EPSD	ICGC;COSMIC	20.411	Up-regulation
CK1_CK1_CK1-A_CSNK1A1_ST	P08238	HSP90AB1	P48729	CSNK1A1	S468	R475C	475	Missense	distal	7	no	24.642	24.688	EPSD	ICGC;COSMIC	20.411	Up-regulation
CK1_CK1_CK1-A_CSNK1A1_ST	P08238	HSP90AB1	P48729	CSNK1A1	S468	R475H	475	Missense	distal	7	no	24.642	24.768	EPSD	ICGC;COSMIC	20.411	Up-regulation
CK1_CK1_CK1-A_CSNK1A1_ST	P08238	HSP90AB1	P48729	CSNK1A1	S468	Q461H	461	Missense	distal	-7	no	24.642	23.471	EPSD	ICGC	20.411	Down-regulation
CK1_CK1_CK1-A_CSNK1A1_ST	P08238	HSP90AB1	P48729	CSNK1A1	S468	M466I	466	Missense	proximal	-2	no	24.642	23.733	EPSD	ICGC;COSMIC	20.411	Down-regulation
CK1_CK1_CK1-A_CSNK1A1_ST	P08238	HSP90AB1	P48729	CSNK1A1	S669	S666F	666	Missense	distal	-3	no	25.613	19.960	EPSD	ICGC;COSMIC	20.411	Loss
CK1_CK1_CK1-A_CSNK1A1_ST	O75581	LRP6	P48729	CSNK1A1	S171	R173L	173	Missense	proximal	2	no	21.268	20.889	EPSD	ICGC;COSMIC	20.411	Down-regulation
CK1_CK1_CK1-A_CSNK1A1_ST	O75581	LRP6	P48729	CSNK1A1	S171	N178K	178	Missense	distal	7	no	21.268	21.227	EPSD	ICGC	20.411	Down-regulation
CK1_CK1_CK1-A_CSNK1A1_ST	O75581	LRP6	P48729	CSNK1A1	S172	R173L	173	Missense	proximal	1	no	25.826	26.142	EPSD	ICGC;COSMIC	20.411	Up-regulation
CK1_CK1_CK1-A_CSNK1A1_ST	O75581	LRP6	P48729	CSNK1A1	S172	N178K	178	Missense	distal	6	no	25.826	25.659	EPSD	ICGC	20.411	Down-regulation
CK1_CK1_CK1-A_CSNK1A1_ST	Q12778	FOXO1	P48729	CSNK1A1	S164	N158K	158	Missense	distal	-6	no	21.680	21.746	EPSD	ICGC	20.411	Up-regulation
CK1_CK1_CK1-A_CSNK1A1_ST	Q12778	FOXO1	P48729	CSNK1A1	S205	G208D	208	Missense	distal	3	no	30.590	30.864	EPSD	ICGC;COSMIC;GDSC;CCLE	20.411	Up-regulation
CK1_CK1_CK1-A_CSNK1A1_ST	Q12778	FOXO1	P48729	CSNK1A1	S206	G208D	208	Missense	proximal	2	no	20.936	20.732	EPSD	ICGC;COSMIC;GDSC;CCLE	20.411	Down-regulation
CK1_CK1_CK1-A_CSNK1A1_ST	Q12778	FOXO1	P48729	CSNK1A1	S212	L219I	219	Missense	distal	7	no	24.169	24.043	EPSD	ICGC;COSMIC	20.411	Down-regulation
CK1_CK1_CK1-A_CSNK1A1_ST	Q12778	FOXO1	P48729	CSNK1A1	S212	G208D	208	Missense	distal	-4	no	24.169	24.998	EPSD	ICGC;COSMIC;GDSC;CCLE	20.411	Up-regulation
CK1_CK1_CK1-A_CSNK1A1_ST	Q12778	FOXO1	P48729	CSNK1A1	S287	S293Y	293	Missense	distal	6	no	21.575	20.999	EPSD	ICGC;COSMIC	20.411	Down-regulation
CK1_CK1_CK1-A_CSNK1A1_ST	Q12778	FOXO1	P48729	CSNK1A1	S287	A284D	284	Missense	distal	-3	no	21.575	26.402	EPSD	ICGC	20.411	Up-regulation
CK1_CK1_CK1-A_CSNK1A1_ST	Q12778	FOXO1	P48729	CSNK1A1	S287	Q281K	281	Missense	distal	-6	no	21.575	20.966	EPSD	ICGC;COSMIC	20.411	Down-regulation
CK1_CK1_CK1-A_CSNK1A1_ST	Q12778	FOXO1	P48729	CSNK1A1	S303	N309S	309	Missense	distal	6	no	21.233	21.450	EPSD	ICGC;COSMIC	20.411	Up-regulation
CK1_CK1_CK1-A_CSNK1A1_ST	Q12778	FOXO1	P48729	CSNK1A1	S311	N309S	309	Missense	proximal	-2	no	19.506	21.748	EPSD	ICGC;COSMIC	20.411	Gain
CK1_CK1_CK1-A_CSNK1A1_ST	Q12778	FOXO1	P48729	CSNK1A1	S322	G326V	326	Missense	distal	4	no	25.541	25.416	EPSD;PhosphoSitePlus	ICGC;COSMIC	20.411	Down-regulation
CK1_CK1_CK1-A_CSNK1A1_ST	Q12778	FOXO1	P48729	CSNK1A1	S325	G326V	326	Missense	proximal	1	no	21.238	21.004	PhosphoSitePlus;EPSD	ICGC;COSMIC	20.411	Down-regulation
CK1_CK1_CK1-A_CSNK1A1_ST	Q12778	FOXO1	P48729	CSNK1A1	S509	A511V	511	Missense	proximal	2	no	20.770	20.327	EPSD	ICGC;COSMIC	20.411	Loss
CK1_CK1_CK1-A_CSNK1A1_ST	P40337	VHL	P48729	CSNK1A1	S33	E32D	32	Missense	proximal	-1	no	25.228	24.598	EPSD	ICGC	20.411	Down-regulation
CK1_CK1_CK1-A_CSNK1A1_ST	P40337	VHL	P48729	CSNK1A1	S33	G34S	34	Missense	proximal	1	no	25.228	25.008	EPSD	ICGC;COSMIC	20.411	Down-regulation
CK1_CK1_CK1-A_CSNK1A1_ST	P40337	VHL	P48729	CSNK1A1	S38	E32D	32	Missense	distal	-6	no	24.264	25.200	EPSD	ICGC	20.411	Up-regulation
CK1_CK1_CK1-A_CSNK1A1_ST	P40337	VHL	P48729	CSNK1A1	S38	E41K	41	Missense	distal	3	no	24.264	20.134	EPSD	ICGC	20.411	Loss
CK1_CK1_CK1-A_CSNK1A1_ST	P40337	VHL	P48729	CSNK1A1	S38	G34S	34	Missense	distal	-4	no	24.264	24.099	EPSD	ICGC;COSMIC	20.411	Down-regulation
CK1_CK1_CK1-A_CSNK1A1_ST	P40337	VHL	P48729	CSNK1A1	S72	P71R	71	Missense	proximal	-1	no	21.150	20.677	PhosphoSitePlus	ICGC;COSMIC	20.411	Down-regulation
CK1_CK1_CK1-A_CSNK1A1_ST	P40337	VHL	P48729	CSNK1A1	S72	V74G	74	Missense	proximal	2	no	21.150	22.769	PhosphoSitePlus	ICGC;COSMIC	20.411	Up-regulation
CK1_CK1_CK1-A_CSNK1A1_ST	P40337	VHL	P48729	CSNK1A1	S72	N78I	78	Missense	distal	6	no	21.150	21.365	PhosphoSitePlus	ICGC;COSMIC	20.411	Up-regulation
CK1_CK1_CK1-A_CSNK1A1_ST	P40337	VHL	P48729	CSNK1A1	S72	N78S	78	Missense	distal	6	no	21.150	21.367	PhosphoSitePlus	ICGC;COSMIC	20.411	Up-regulation
CK1_CK1_CK1-A_CSNK1A1_ST	P40337	VHL	P48729	CSNK1A1	S72	S65L	65	Missense	distal	-7	no	21.150	20.470	PhosphoSitePlus	ICGC;COSMIC	20.411	Down-regulation
CK1_CK1_CK1-A_CSNK1A1_ST	P40337	VHL	P48729	CSNK1A1	S72	N78K	78	Missense	distal	6	no	21.150	20.984	PhosphoSitePlus	ICGC;COSMIC;CCLE	20.411	Down-regulation
CK1_CK1_CK1-A_CSNK1A1_ST	P40337	VHL	P48729	CSNK1A1	S72	S65P	65	Missense	distal	-7	no	21.150	20.485	PhosphoSitePlus	ICGC;COSMIC	20.411	Down-regulation
CK1_CK1_CK1-A_CSNK1A1_ST	P40337	VHL	P48729	CSNK1A1	S72	R79P	79	Missense	distal	7	no	21.150	21.231	PhosphoSitePlus	ICGC;COSMIC	20.411	Up-regulation
CK1_CK1_CK1-A_CSNK1A1_ST	P40337	VHL	P48729	CSNK1A1	S72	R79H	79	Missense	distal	7	no	21.150	21.276	PhosphoSitePlus	ICGC;COSMIC	20.411	Up-regulation
CK1_CK1_CK1-A_CSNK1A1_ST	P40337	VHL	P48729	CSNK1A1	S72	V74A	74	Missense	proximal	2	no	21.150	21.593	PhosphoSitePlus	ICGC;COSMIC	20.411	Up-regulation
CK1_CK1_CK1-A_CSNK1A1_ST	Q13158	FADD	P48729	CSNK1A1	S16	V11L	11	Missense	distal	-5	no	23.399	24.529	EPSD	ICGC	20.411	Up-regulation
CK1_CK1_CK1-A_CSNK1A1_ST	Q13158	FADD	P48729	CSNK1A1	S16	S14I	14	Missense	proximal	-2	no	23.399	21.219	EPSD	ICGC;COSMIC	20.411	Down-regulation
CK1_CK1_CK1-A_CSNK1A1_ST	Q13501	SQSTM1	P48729	CSNK1A1	S152	K157Q	157	Missense	distal	5	no	20.756	20.220	EPSD	ICGC;COSMIC	20.411	Loss
CK1_CK1_CK1-A_CSNK1A1_ST	Q13501	SQSTM1	P48729	CSNK1A1	S152	C151F	151	Missense	proximal	-1	no	20.756	21.234	EPSD	ICGC	20.411	Up-regulation
CK1_CK1_CK1-A_CSNK1A1_ST	Q13501	SQSTM1	P48729	CSNK1A1	S152	D149E	149	Missense	distal	-3	no	20.756	18.281	EPSD	ICGC	20.411	Loss
CK1_CK1_CK1-A_CSNK1A1_ST	Q13501	SQSTM1	P48729	CSNK1A1	S170	A167E	167	Missense	distal	-3	no	19.275	21.627	EPSD	ICGC	20.411	Gain
CK1_CK1_CK1-A_CSNK1A1_ST	Q13501	SQSTM1	P48729	CSNK1A1	S176	R183P	183	Missense	distal	7	no	20.545	20.626	EPSD	ICGC;COSMIC	20.411	Up-regulation
CK1_CK1_CK1-A_CSNK1A1_ST	Q13501	SQSTM1	P48729	CSNK1A1	S180	R186Q	186	Missense	distal	6	no	26.136	26.052	EPSD	ICGC;COSMIC	20.411	Down-regulation
CK1_CK1_CK1-A_CSNK1A1_ST	Q13501	SQSTM1	P48729	CSNK1A1	S180	R183P	183	Missense	distal	3	no	26.136	24.314	EPSD	ICGC;COSMIC	20.411	Down-regulation
CK1_CK1_CK1-A_CSNK1A1_ST	Q13501	SQSTM1	P48729	CSNK1A1	S182	R186Q	186	Missense	distal	4	no	21.169	21.071	EPSD	ICGC;COSMIC	20.411	Down-regulation
CK1_CK1_CK1-A_CSNK1A1_ST	Q13501	SQSTM1	P48729	CSNK1A1	S182	R183P	183	Missense	proximal	1	no	21.169	21.375	EPSD	ICGC;COSMIC	20.411	Up-regulation
CK1_CK1_CK1-A_CSNK1A1_ST	Q13501	SQSTM1	P48729	CSNK1A1	S182	V188L	188	Missense	distal	6	no	21.169	21.490	EPSD	ICGC;COSMIC	20.411	Up-regulation
CK1_CK1_CK1-A_CSNK1A1_ST	Q13501	SQSTM1	P48729	CSNK1A1	S224	G219D	219	Missense	distal	-5	no	23.092	22.877	EPSD	ICGC	20.411	Down-regulation
CK1_CK1_CK1-A_CSNK1A1_ST	Q13501	SQSTM1	P48729	CSNK1A1	S226	P232L	232	Missense	distal	6	no	26.569	26.655	EPSD	ICGC;COSMIC	20.411	Up-regulation
CK1_CK1_CK1-A_CSNK1A1_ST	Q13501	SQSTM1	P48729	CSNK1A1	S226	G219D	219	Missense	distal	-7	no	26.569	25.778	EPSD	ICGC	20.411	Down-regulation
CK1_CK1_CK1-A_CSNK1A1_ST	Q13501	SQSTM1	P48729	CSNK1A1	S226	S233I	233	Missense	distal	7	no	26.569	26.479	EPSD	ICGC	20.411	Down-regulation
CK1_CK1_CK1-A_CSNK1A1_ST	Q13501	SQSTM1	P48729	CSNK1A1	S229	P232L	232	Missense	distal	3	no	20.534	21.047	EPSD	ICGC;COSMIC	20.411	Up-regulation
CK1_CK1_CK1-A_CSNK1A1_ST	Q13501	SQSTM1	P48729	CSNK1A1	S229	S233I	233	Missense	distal	4	no	20.534	20.555	EPSD	ICGC	20.411	Up-regulation
CK1_CK1_CK1-A_CSNK1A1_ST	Q13501	SQSTM1	P48729	CSNK1A1	S233	P232L	232	Missense	proximal	-1	no	24.084	23.800	EPSD	ICGC;COSMIC	20.411	Down-regulation
CK1_CK1_CK1-A_CSNK1A1_ST	Q13501	SQSTM1	P48729	CSNK1A1	S233	S233I	233	Missense	central	0	yes	24.084	0.000	EPSD	ICGC	20.411	Loss
CK1_CK1_CK1-A_CSNK1A1_ST	Q13501	SQSTM1	P48729	CSNK1A1	S282	S284L	284	Missense	proximal	2	no	21.022	20.037	EPSD	ICGC;COSMIC	20.411	Loss
CK1_CK1_CK1-A_CSNK1A1_ST	Q13501	SQSTM1	P48729	CSNK1A1	S291	S284L	284	Missense	distal	-7	no	22.276	21.596	EPSD	ICGC;COSMIC	20.411	Down-regulation
CK1_CK1_CK1-A_CSNK1A1_ST	Q13501	SQSTM1	P48729	CSNK1A1	S291	P296L	296	Missense	distal	5	no	22.276	22.341	EPSD	ICGC;COSMIC	20.411	Up-regulation
CK1_CK1_CK1-A_CSNK1A1_ST	Q13501	SQSTM1	P48729	CSNK1A1	S291	G297C	297	Missense	distal	6	no	22.276	21.833	EPSD	ICGC	20.411	Down-regulation
CK1_CK1_CK1-A_CSNK1A1_ST	P07910	HNRNPC	P48729	CSNK1A1	S107	A102E	102	Missense	distal	-5	no	23.470	24.141	EPSD	ICGC	20.411	Up-regulation
CK1_CK1_CK1-A_CSNK1A1_ST	P07910	HNRNPC	P48729	CSNK1A1	S107	G106C	106	Missense	proximal	-1	no	23.470	21.592	EPSD	ICGC;COSMIC	20.411	Down-regulation
CK1_CK1_CK1-A_CSNK1A1_ST	P07910	HNRNPC	P48729	CSNK1A1	S238	S233T	233	Missense	distal	-5	no	23.809	23.177	EPSD	ICGC;COSMIC	20.411	Down-regulation
CK1_CK1_CK1-A_CSNK1A1_ST	P07910	HNRNPC	P48729	CSNK1A1	S239	S233T	233	Missense	distal	-6	no	22.141	21.760	EPSD	ICGC;COSMIC	20.411	Down-regulation
CK1_CK1_CK1-A_CSNK1A1_ST	P07910	HNRNPC	P48729	CSNK1A1	S299	A300T	300	Missense	proximal	1	no	23.605	23.650	EPSD;PhosphoSitePlus	ICGC;COSMIC	20.411	Up-regulation
CK1_CK1_CK1-A_CSNK1A1_ST	Q8TB45	DEPTOR	P48729	CSNK1A1	S6	G8C	8	Missense	proximal	2	no	22.103	20.773	EPSD	ICGC	20.411	Down-regulation
CK1_CK1_CK1-A_CSNK1A1_ST	Q8TB45	DEPTOR	P48729	CSNK1A1	S6	G5C	5	Missense	proximal	-1	no	22.103	20.225	EPSD	ICGC	20.411	Loss
CK1_CK1_CK1-A_CSNK1A1_ST	Q8TB45	DEPTOR	P48729	CSNK1A1	S9	G8C	8	Missense	proximal	-1	no	26.033	24.155	EPSD	ICGC	20.411	Down-regulation
CK1_CK1_CK1-A_CSNK1A1_ST	Q8TB45	DEPTOR	P48729	CSNK1A1	S9	G5C	5	Missense	distal	-4	no	26.033	23.168	EPSD	ICGC	20.411	Down-regulation
CK1_CK1_CK1-A_CSNK1A1_ST	Q8TB45	DEPTOR	P48729	CSNK1A1	S12	G8C	8	Missense	distal	-4	no	28.750	25.885	EPSD	ICGC	20.411	Down-regulation
CK1_CK1_CK1-A_CSNK1A1_ST	Q8TB45	DEPTOR	P48729	CSNK1A1	S12	G5C	5	Missense	distal	-7	no	28.750	27.042	EPSD	ICGC	20.411	Down-regulation
CK1_CK1_CK1-A_CSNK1A1_ST	Q8TB45	DEPTOR	P48729	CSNK1A1	S15	G8C	8	Missense	distal	-7	no	24.411	22.702	EPSD	ICGC	20.411	Down-regulation
CK1_CK1_CK1-A_CSNK1A1_ST	Q04206	RELA	P48729	CSNK1A1	S45	G48S	48	Missense	distal	3	no	22.650	22.202	EPSD	ICGC;COSMIC	20.411	Down-regulation
CK1_CK1_CK1-A_CSNK1A1_ST	Q04206	RELA	P48729	CSNK1A1	S45	R41H	41	Missense	distal	-4	no	22.650	20.609	EPSD	ICGC;COSMIC	20.411	Down-regulation
CK1_CK1_CK1-A_CSNK1A1_ST	Q04206	RELA	P48729	CSNK1A1	S131	R133C	133	Missense	proximal	2	no	21.220	20.841	EPSD	ICGC	20.411	Down-regulation
CK1_CK1_CK1-A_CSNK1A1_ST	Q04206	RELA	P48729	CSNK1A1	S131	D125E	125	Missense	distal	-6	no	21.220	20.284	EPSD	ICGC	20.411	Loss
CK1_CK1_CK1-A_CSNK1A1_ST	Q04206	RELA	P48729	CSNK1A1	S131	E127Q	127	Missense	distal	-4	no	21.220	20.842	EPSD	ICGC;COSMIC	20.411	Down-regulation
CK1_CK1_CK1-A_CSNK1A1_ST	Q04206	RELA	P48729	CSNK1A1	S205	R198Q	198	Missense	distal	-7	no	20.979	20.665	EPSD	ICGC	20.411	Down-regulation
CK1_CK1_CK1-A_CSNK1A1_ST	Q04206	RELA	P48729	CSNK1A1	S205	S203Y	203	Missense	proximal	-2	no	20.979	18.936	EPSD	ICGC	20.411	Loss
CK1_CK1_CK1-A_CSNK1A1_ST	Q04206	RELA	P48729	CSNK1A1	S238	A235S	235	Missense	distal	-3	no	20.005	24.461	EPSD	ICGC;COSMIC	20.411	Gain
CK1_CK1_CK1-A_CSNK1A1_ST	Q04206	RELA	P48729	CSNK1A1	S238	R236Q	236	Missense	proximal	-2	no	20.005	20.512	EPSD	ICGC;COSMIC	20.411	Gain
CK1_CK1_CK1-A_CSNK1A1_ST	Q04206	RELA	P48729	CSNK1A1	S316	P317H	317	Missense	proximal	1	no	21.058	20.765	PhosphoSitePlus	ICGC;COSMIC	20.411	Down-regulation
CK1_CK1_CK1-A_CSNK1A1_ST	Q04206	RELA	P48729	CSNK1A1	S316	S311G	311	Missense	distal	-5	no	21.058	21.351	PhosphoSitePlus	ICGC;COSMIC	20.411	Up-regulation
CK1_CK1_CK1-A_CSNK1A1_ST	Q04206	RELA	P48729	CSNK1A1	S316	G320R	320	Missense	distal	4	no	21.058	21.057	PhosphoSitePlus	ICGC	20.411	Down-regulation
CK1_CK1_CK1-A_CSNK1A1_ST	Q04206	RELA	P48729	CSNK1A1	S316	T322I	322	Missense	distal	6	no	21.058	21.159	PhosphoSitePlus	ICGC;COSMIC	20.411	Up-regulation
CK1_CK1_CK1-A_CSNK1A1_ST	O60346	PHLPP1	P48729	CSNK1A1	S141	A136T	136	Missense	distal	-5	no	21.182	21.863	EPSD	ICGC	20.411	Up-regulation
CK1_CK1_CK1-A_CSNK1A1_ST	O60346	PHLPP1	P48729	CSNK1A1	S142	A136T	136	Missense	distal	-6	no	23.204	23.731	EPSD	ICGC	20.411	Up-regulation
CK1_CK1_CK1-A_CSNK1A1_ST	O60346	PHLPP1	P48729	CSNK1A1	S143	A136T	136	Missense	distal	-7	no	21.270	20.299	EPSD	ICGC	20.411	Loss
CK1_CK1_CK1-A_CSNK1A1_ST	P07900	HSP90AA1	P48729	CSNK1A1	S129	S129F	129	Missense	central	0	yes	20.709	0.000	EPSD	ICGC;COSMIC	20.411	Loss
CK1_CK1_CK1-A_CSNK1A1_ST	P07900	HSP90AA1	P48729	CSNK1A1	S129	G132R	132	Missense	distal	3	no	20.709	17.818	EPSD	ICGC;COSMIC	20.411	Loss
CK1_CK1_CK1-A_CSNK1A1_ST	P07900	HSP90AA1	P48729	CSNK1A1	S129	M130I	130	Missense	proximal	1	no	20.709	20.939	EPSD	ICGC;COSMIC	20.411	Up-regulation
CK1_CK1_CK1-A_CSNK1A1_ST	P07900	HSP90AA1	P48729	CSNK1A1	S164	A161P	161	Missense	distal	-3	no	22.439	20.708	EPSD	ICGC;COSMIC	20.411	Down-regulation
CK1_CK1_CK1-A_CSNK1A1_ST	P07900	HSP90AA1	P48729	CSNK1A1	S164	S165L	165	Missense	proximal	1	no	22.439	22.702	EPSD	ICGC;COSMIC	20.411	Up-regulation
CK1_CK1_CK1-A_CSNK1A1_ST	P07900	HSP90AA1	P48729	CSNK1A1	S164	S164Y	164	Missense	central	0	yes	22.439	0.000	EPSD	ICGC	20.411	Loss
CK1_CK1_CK1-A_CSNK1A1_ST	P07900	HSP90AA1	P48729	CSNK1A1	S165	A161P	161	Missense	distal	-4	no	26.788	25.696	EPSD	ICGC;COSMIC	20.411	Down-regulation
CK1_CK1_CK1-A_CSNK1A1_ST	P07900	HSP90AA1	P48729	CSNK1A1	S165	S165L	165	Missense	central	0	yes	26.788	0.000	EPSD	ICGC;COSMIC	20.411	Loss
CK1_CK1_CK1-A_CSNK1A1_ST	P07900	HSP90AA1	P48729	CSNK1A1	S165	S164Y	164	Missense	proximal	-1	no	26.788	25.902	EPSD	ICGC	20.411	Down-regulation
CK1_CK1_CK1-A_CSNK1A1_ST	P07900	HSP90AA1	P48729	CSNK1A1	S263	K269N	269	Missense	distal	6	no	22.114	22.281	EPSD	ICGC;COSMIC	20.411	Up-regulation
CK1_CK1_CK1-A_CSNK1A1_ST	P07900	HSP90AA1	P48729	CSNK1A1	S263	E268G	268	Missense	distal	5	no	22.114	22.459	EPSD	ICGC	20.411	Up-regulation
CK1_CK1_CK1-A_CSNK1A1_ST	P07900	HSP90AA1	P48729	CSNK1A1	T305	R299S	299	Missense	distal	-6	no	21.151	21.679	EPSD	ICGC;COSMIC	20.411	Up-regulation
CK1_CK1_CK1-A_CSNK1A1_ST	P07900	HSP90AA1	P48729	CSNK1A1	T305	G310R	310	Missense	distal	5	no	21.151	21.248	EPSD	ICGC;COSMIC	20.411	Up-regulation
CK1_CK1_CK1-A_CSNK1A1_ST	P07900	HSP90AA1	P48729	CSNK1A1	T305	E307K	307	Missense	proximal	2	no	21.151	20.175	EPSD	ICGC;COSMIC	20.411	Loss
CK1_CK1_CK1-A_CSNK1A1_ST	P07900	HSP90AA1	P48729	CSNK1A1	T305	I304V	304	Missense	proximal	-1	no	21.151	19.660	EPSD	ICGC;COSMIC	20.411	Loss
CK1_CK1_CK1-A_CSNK1A1_ST	P07900	HSP90AA1	P48729	CSNK1A1	T305	F312L	312	Missense	distal	7	no	21.151	20.998	EPSD	ICGC;COSMIC	20.411	Down-regulation
CK1_CK1_CK1-A_CSNK1A1_ST	P07900	HSP90AA1	P48729	CSNK1A1	S476	A469T	469	Missense	distal	-7	no	24.531	23.559	EPSD	ICGC	20.411	Down-regulation
CK1_CK1_CK1-A_CSNK1A1_ST	P07900	HSP90AA1	P48729	CSNK1A1	S476	Y480H	480	Missense	distal	4	no	24.531	24.571	EPSD	ICGC;COSMIC	20.411	Up-regulation
CK1_CK1_CK1-A_CSNK1A1_ST	P07900	HSP90AA1	P48729	CSNK1A1	S677	H684R	684	Missense	distal	7	no	26.288	26.162	EPSD	ICGC;COSMIC	20.411	Down-regulation
CK1_CK1_CK1-A_CSNK1A1_ST	P07900	HSP90AA1	P48729	CSNK1A1	T704	A710S	710	Missense	distal	6	no	24.123	24.481	EPSD	ICGC;COSMIC	20.411	Up-regulation
CK1_CK1_CK1-A_CSNK1A1_ST	P07900	HSP90AA1	P48729	CSNK1A1	T704	D702G	702	Missense	proximal	-2	no	24.123	24.090	EPSD	ICGC;COSMIC	20.411	Down-regulation
CK1_CK1_CK1-A_CSNK1A1_ST	P07900	HSP90AA1	P48729	CSNK1A1	T704	D701H	701	Missense	distal	-3	no	24.123	17.885	EPSD	ICGC;COSMIC	20.411	Loss
CK1_CK1_CK1-A_CSNK1A1_ST	P07900	HSP90AA1	P48729	CSNK1A1	T704	A705D	705	Missense	proximal	1	no	24.123	24.333	EPSD	ICGC	20.411	Up-regulation
CK1_CK1_CK1-A_CSNK1A1_ST	P07900	HSP90AA1	P48729	CSNK1A1	T704	T708A	708	Missense	distal	4	no	24.123	24.134	EPSD	ICGC	20.411	Up-regulation
CK1_CK1_CK1-A_CSNK1A1_ST	P07900	HSP90AA1	P48729	CSNK1A1	T704	A711V	711	Missense	distal	7	no	24.123	24.242	EPSD	ICGC	20.411	Up-regulation
CK1_CK1_CK1-A_CSNK1A1_ST	P07900	HSP90AA1	P48729	CSNK1A1	S726	S726L	726	Missense	central	0	yes	21.702	0.000	PhosphoSitePlus;EPSD	ICGC;COSMIC	20.411	Loss
CK1_CK1_CK1-A_CSNK1A1_ST	P07900	HSP90AA1	P48729	CSNK1A1	S726	T725I	725	Missense	proximal	-1	no	21.702	22.857	PhosphoSitePlus;EPSD	ICGC	20.411	Up-regulation
CK1_CK1_CK1-A_CSNK1A1_ST	P07900	HSP90AA1	P48729	CSNK1A1	S726	R727H	727	Missense	proximal	1	no	21.702	21.616	PhosphoSitePlus;EPSD	ICGC;COSMIC	20.411	Down-regulation
CK1_CK1_CK1-A_CSNK1A1_ST	P07900	HSP90AA1	P48729	CSNK1A1	S726	G721V	721	Missense	distal	-5	no	21.702	19.649	PhosphoSitePlus;EPSD	ICGC;COSMIC	20.411	Loss
CK1_CK1_CK1-A_CSNK1A1_ST	P01106	MYC	P48729	CSNK1A1	S252	E257V	257	Missense	distal	5	no	22.474	22.857	PhosphoSitePlus;EPSD	ICGC	20.411	Up-regulation
CK1_CK1_CK1-A_CSNK1A1_ST	P35222	CTNNB1	P48729	CSNK1A1	S715	R710H	710	Missense	distal	-5	no	24.180	23.682	EPSD	ICGC;COSMIC	20.411	Down-regulation
CK1_CK1_CK1-A_CSNK1A1_ST	Q9H6E5	TUT1	P48729	CSNK1A1	S115	R122H	122	Missense	distal	7	no	22.193	22.319	EPSD	ICGC;COSMIC	20.411	Up-regulation
CK1_CK1_CK1-A_CSNK1A1_ST	Q9H6E5	TUT1	P48729	CSNK1A1	S115	R122C	122	Missense	distal	7	no	22.193	22.239	EPSD	ICGC;COSMIC	20.411	Up-regulation
CK1_CK1_CK1-A_CSNK1A1_ST	Q9H6E5	TUT1	P48729	CSNK1A1	S136	P134T	134	Missense	proximal	-2	no	20.040	20.777	EPSD	ICGC	20.411	Gain
CK1_CK1_CK1-A_CSNK1A1_ST	Q9H6E5	TUT1	P48729	CSNK1A1	S383	S383F	383	Missense	central	0	yes	22.086	0.000	EPSD	ICGC;COSMIC	20.411	Loss
CK1_CK1_CK1-A_CSNK1A1_ST	Q9H6E5	TUT1	P48729	CSNK1A1	S383	R387W	387	Missense	distal	4	no	22.086	21.811	EPSD	ICGC;COSMIC	20.411	Down-regulation
CK1_CK1_CK1-A_CSNK1A1_ST	Q9H6E5	TUT1	P48729	CSNK1A1	S383	S383P	383	Missense	central	0	yes	22.086	0.000	EPSD	ICGC	20.411	Loss
CK1_CK1_CK1-A_CSNK1A1_ST	Q9H6E5	TUT1	P48729	CSNK1A1	S513	R515L	515	Missense	proximal	2	no	23.746	23.367	EPSD	ICGC;COSMIC	20.411	Down-regulation
CK1_CK1_CK1-A_CSNK1A1_ST	Q9H6E5	TUT1	P48729	CSNK1A1	S513	R515Q	515	Missense	proximal	2	no	23.746	24.037	EPSD	ICGC	20.411	Up-regulation
CK1_CK1_CK1-A_CSNK1A1_ST	Q9H6E5	TUT1	P48729	CSNK1A1	S652	Q654E	654	Missense	proximal	2	no	26.375	26.641	EPSD	ICGC;COSMIC	20.411	Up-regulation
CK1_CK1_CK1-A_CSNK1A1_ST	Q9H6E5	TUT1	P48729	CSNK1A1	S653	Q654E	654	Missense	proximal	1	no	26.587	26.603	EPSD	ICGC;COSMIC	20.411	Up-regulation
CK1_CK1_CK1-A_CSNK1A1_ST	Q9H6E5	TUT1	P48729	CSNK1A1	S658	D664N	664	Missense	distal	6	no	21.021	20.874	EPSD	ICGC	20.411	Down-regulation
CK1_CK1_CK1-A_CSNK1A1_ST	Q9H6E5	TUT1	P48729	CSNK1A1	S658	V663L	663	Missense	distal	5	no	21.021	20.983	EPSD	ICGC;COSMIC	20.411	Down-regulation
CK1_CK1_CK1-A_CSNK1A1_ST	Q9H6E5	TUT1	P48729	CSNK1A1	S658	Q654E	654	Missense	distal	-4	no	21.021	21.398	EPSD	ICGC;COSMIC	20.411	Up-regulation
CK1_CK1_CK1-A_CSNK1A1_ST	Q9H6E5	TUT1	P48729	CSNK1A1	S707	A704T	704	Missense	distal	-3	no	20.029	20.721	EPSD	ICGC;COSMIC	20.411	Gain
CK1_CK1_CK1-A_CSNK1A1_ST	Q9H6E5	TUT1	P48729	CSNK1A1	S731	A733T	733	Missense	proximal	2	no	21.360	21.398	EPSD	ICGC;COSMIC;GDSC	20.411	Up-regulation
CK1_CK1_CK1-A_CSNK1A1_ST	Q9H6E5	TUT1	P48729	CSNK1A1	S731	R738W	738	Missense	distal	7	no	21.360	21.736	EPSD	ICGC;COSMIC	20.411	Up-regulation
CK1_CK1_CK1-A_CSNK1A1_ST	Q9H6E5	TUT1	P48729	CSNK1A1	S750	A745T	745	Missense	distal	-5	no	27.025	27.705	EPSD	ICGC;COSMIC	20.411	Up-regulation
CK1_CK1_CK1-A_CSNK1A1_ST	P63104	YWHAZ	P48729	CSNK1A1	S37	N38Y	38	Missense	proximal	1	no	23.184	23.170	EPSD	ICGC	20.411	Down-regulation
CK1_CK1_CK1-A_CSNK1A1_ST	P63104	YWHAZ	P48729	CSNK1A1	S207	A201S	201	Missense	distal	-6	no	22.466	23.374	EPSD	ICGC;COSMIC	20.411	Up-regulation
CK1_CK1_CK1-A_CSNK1A1_ST	P63104	YWHAZ	P48729	CSNK1A1	S210	I217V	217	Missense	distal	7	no	22.266	22.555	EPSD	ICGC;COSMIC	20.411	Up-regulation
CK1_CK1_CK1-A_CSNK1A1_ST	P63104	YWHAZ	P48729	CSNK1A1	S210	L216I	216	Missense	distal	6	no	22.266	22.403	EPSD	ICGC	20.411	Up-regulation
CK1_CK1_CK1-A_CSNK1A1_ST	P63104	YWHAZ	P48729	CSNK1A1	S210	T215K	215	Missense	distal	5	no	22.266	22.466	EPSD	ICGC	20.411	Up-regulation
CK1_CK1_CK1-A_CSNK1A1_ST	P56537	EIF6	P48729	CSNK1A1	S87	H83Q	83	Missense	distal	-4	no	17.310	21.565	EPSD	ICGC;COSMIC	20.411	Gain
CK1_CK1_CK1-A_CSNK1A1_ST	P56537	EIF6	P48729	CSNK1A1	S174	D169E	169	Missense	distal	-5	no	25.943	25.223	EPSD;PhosphoSitePlus	ICGC	20.411	Down-regulation
CK1_CK1_CK1-A_CSNK1A1_ST	P56537	EIF6	P48729	CSNK1A1	S175	D169E	169	Missense	distal	-6	no	25.296	24.360	PhosphoSitePlus;EPSD	ICGC	20.411	Down-regulation
CK1_CK1_CK1-A_CSNK1A1_ST	P67809	YBX1	P48729	CSNK1A1	S176	P178T	178	Missense	proximal	2	no	22.471	22.694	PhosphoSitePlus	ICGC;COSMIC	20.411	Up-regulation
CK1_CK1_CK1-A_CSNK1A1_ST	P30304	CDC25A	P48729	CSNK1A1	S82	S88F	88	Missense	distal	6	no	23.603	23.025	PhosphoSitePlus;EPSD	ICGC;COSMIC	20.411	Down-regulation
CK1_CK1_CK1-A_CSNK1A1_ST	P42892	ECE1	P48729	CSNK1A1	S34	D30E	30	Missense	distal	-4	no	22.472	22.036	EPSD;PhosphoSitePlus	ICGC	20.411	Down-regulation
CK1_CK1_CK1-A_CSNK1A1_ST	P42892	ECE1	P48729	CSNK1A1	S36	D30E	30	Missense	distal	-6	no	23.841	22.905	PhosphoSitePlus;EPSD	ICGC	20.411	Down-regulation
CK1_CK1_CK1-A_CSNK1A1_ST	O60341	KDM1A	P48729	CSNK1A1	S166	G173R	173	Missense	distal	7	no	20.450	20.535	EPSD	ICGC	20.411	Up-regulation
CK1_CK1_CK1-A_CSNK1A1_ST	O60341	KDM1A	P48729	CSNK1A1	S166	S172L	172	Missense	distal	6	no	20.450	20.310	EPSD	ICGC;COSMIC	20.411	Loss
CK1_CK1_CK1-A_CSNK1A1_ST	P78362	SRPK2	P48729	CSNK1A1	S9	P14L	14	Missense	distal	5	no	20.714	20.778	EPSD	ICGC	20.411	Up-regulation
CK1_CK1_CK1-A_CSNK1A1_ST	P78362	SRPK2	P48729	CSNK1A1	S9	E6D	6	Missense	distal	-3	no	20.714	23.189	EPSD	ICGC;COSMIC	20.411	Up-regulation
CK1_CK1_CK1-A_CSNK1A1_ST	P78362	SRPK2	P48729	CSNK1A1	S486	Q480K	480	Missense	distal	-6	no	26.811	26.202	EPSD	ICGC	20.411	Down-regulation
CK1_CK1_CK1-A_CSNK1A1_ST	P78362	SRPK2	P48729	CSNK1A1	S486	D488Y	488	Missense	proximal	2	no	26.811	25.345	EPSD	ICGC;COSMIC	20.411	Down-regulation
CK1_CK1_CK1-A_CSNK1A1_ST	P78362	SRPK2	P48729	CSNK1A1	S486	V493L	493	Missense	distal	7	no	26.811	26.648	EPSD	ICGC;COSMIC	20.411	Down-regulation
CK1_CK1_CK1-A_CSNK1A1_ST	P78362	SRPK2	P48729	CSNK1A1	S486	E482D	482	Missense	distal	-4	no	26.811	27.247	EPSD	ICGC;COSMIC	20.411	Up-regulation
CK1_CK1_CK1-A_CSNK1A1_ST	P78362	SRPK2	P48729	CSNK1A1	S497	P502T	502	Missense	distal	5	no	22.959	22.923	PhosphoSitePlus	ICGC	20.411	Down-regulation
CK1_CK1_CK1-A_CSNK1A1_ST	P78362	SRPK2	P48729	CSNK1A1	S497	D500N	500	Missense	distal	3	no	22.959	19.759	PhosphoSitePlus	ICGC;COSMIC	20.411	Loss
CK1_CK1_CK1-A_CSNK1A1_ST	P78362	SRPK2	P48729	CSNK1A1	S497	V493L	493	Missense	distal	-4	no	22.959	21.936	PhosphoSitePlus	ICGC;COSMIC	20.411	Down-regulation
CK1_CK1_CK1-A_CSNK1A1_ST	P78362	SRPK2	P48729	CSNK1A1	S497	D500Y	500	Missense	distal	3	no	22.959	19.432	PhosphoSitePlus	ICGC;COSMIC	20.411	Loss
CK1_CK1_CK1-A_CSNK1A1_ST	O94916	NFAT5	P48729	CSNK1A1	S7	S3P	3	Missense	distal	-4	no	20.558	17.866	EPSD	ICGC;COSMIC	20.411	Loss
CK1_CK1_CK1-A_CSNK1A1_ST	O14503	BHLHE40	P48729	CSNK1A1	S235	G232W	232	Missense	distal	-3	no	23.462	24.197	EPSD	ICGC	20.411	Up-regulation
CK1_CK1_CK1-A_CSNK1A1_ST	O14503	BHLHE40	P48729	CSNK1A1	S237	G232W	232	Missense	distal	-5	no	24.300	22.347	EPSD	ICGC	20.411	Down-regulation
CK1_CK1_CK1-A_CSNK1A1_ST	O14503	BHLHE40	P48729	CSNK1A1	S237	S243G	243	Missense	distal	6	no	24.300	24.318	EPSD	ICGC;COSMIC	20.411	Up-regulation
CK1_CK1_CK1-A_CSNK1A1_ST	O14503	BHLHE40	P48729	CSNK1A1	T239	G232W	232	Missense	distal	-7	no	20.851	18.165	EPSD	ICGC	20.411	Loss
CK1_CK1_CK1-A_CSNK1A1_ST	O14503	BHLHE40	P48729	CSNK1A1	T239	Y245C	245	Missense	distal	6	no	20.851	21.003	EPSD	ICGC;COSMIC	20.411	Up-regulation
CK1_CK1_CK1-A_CSNK1A1_ST	O14503	BHLHE40	P48729	CSNK1A1	T239	S243G	243	Missense	distal	4	no	20.851	20.881	EPSD	ICGC;COSMIC	20.411	Up-regulation
CK1_CK1_CK1-A_CSNK1A1_ST	O14503	BHLHE40	P48729	CSNK1A1	T239	G246K	246	Missense	distal	7	no	20.851	20.834	EPSD	ICGC	20.411	Down-regulation
CK1_CK1_CK1-A_CSNK1A1_ST	O14503	BHLHE40	P48729	CSNK1A1	T241	Y245C	245	Missense	distal	4	no	21.911	21.935	EPSD	ICGC;COSMIC	20.411	Up-regulation
CK1_CK1_CK1-A_CSNK1A1_ST	O14503	BHLHE40	P48729	CSNK1A1	T241	S243G	243	Missense	proximal	2	no	21.911	22.257	EPSD	ICGC;COSMIC	20.411	Up-regulation
CK1_CK1_CK1-A_CSNK1A1_ST	O14503	BHLHE40	P48729	CSNK1A1	T241	G246K	246	Missense	distal	5	no	21.911	22.011	EPSD	ICGC	20.411	Up-regulation
CK1_CK1_CK1-A_CSNK1A1_ST	O14503	BHLHE40	P48729	CSNK1A1	S243	Y245C	245	Missense	proximal	2	no	21.002	21.342	PhosphoSitePlus	ICGC;COSMIC	20.411	Up-regulation
CK1_CK1_CK1-A_CSNK1A1_ST	O14503	BHLHE40	P48729	CSNK1A1	S243	S243G	243	Missense	central	0	yes	21.002	0.000	PhosphoSitePlus	ICGC;COSMIC	20.411	Loss
CK1_CK1_CK1-A_CSNK1A1_ST	O14503	BHLHE40	P48729	CSNK1A1	S243	G246K	246	Missense	distal	3	no	21.002	17.006	PhosphoSitePlus	ICGC	20.411	Loss
CK1_CK1_CK1-A_CSNK1A1_ST	O14503	BHLHE40	P48729	CSNK1A1	S249	S256I	256	Missense	distal	7	no	22.703	22.612	EPSD	ICGC;COSMIC	20.411	Down-regulation
CK1_CK1_CK1-A_CSNK1A1_ST	O14503	BHLHE40	P48729	CSNK1A1	S249	Y245C	245	Missense	distal	-4	no	22.703	22.556	EPSD	ICGC;COSMIC	20.411	Down-regulation
CK1_CK1_CK1-A_CSNK1A1_ST	O14503	BHLHE40	P48729	CSNK1A1	S249	S243G	243	Missense	distal	-6	no	22.703	22.843	EPSD	ICGC;COSMIC	20.411	Up-regulation
CK1_CK1_CK1-A_CSNK1A1_ST	O14503	BHLHE40	P48729	CSNK1A1	S249	G246K	246	Missense	distal	-3	no	22.703	18.370	EPSD	ICGC	20.411	Loss
CK1_CK1_CK1-A_CSNK1A1_ST	O14503	BHLHE40	P48729	CSNK1A1	S249	R255H	255	Missense	distal	6	no	22.703	22.632	EPSD	ICGC;GDSC;CCLE	20.411	Down-regulation
CK1_CK1_CK1-A_CSNK1A1_ST	P37840	SNCA	P48729	CSNK1A1	S87	E83D	83	Missense	distal	-4	no	21.035	21.471	PhosphoSitePlus;EPSD	ICGC;COSMIC	20.411	Up-regulation
TKL_RIPK_RIPK1_ST	Q13546	RIPK1	Q13546	RIPK1	S161	A160S	160	Missense	proximal	-1	no	6.228	6.290	EPSD;PhosphoSitePlus	ICGC	2.812	Up-regulation
TKL_RIPK_RIPK1_ST	Q13546	RIPK1	Q13546	RIPK1	S161	M164I	164	Missense	distal	3	no	6.228	6.165	EPSD;PhosphoSitePlus	ICGC	2.812	Down-regulation
TKL_RIPK_RIPK1_ST	Q13546	RIPK1	Q13546	RIPK1	S161	D156N	156	Missense	distal	-5	no	6.228	6.443	EPSD;PhosphoSitePlus	ICGC;COSMIC	2.812	Up-regulation
TKL_RIPK_RIPK1_ST	Q13546	RIPK1	Q13546	RIPK1	S166	N170T	170	Missense	distal	4	no	6.739	6.537	EPSD;PhosphoSitePlus	ICGC;COSMIC	2.812	Down-regulation
TKL_RIPK_RIPK1_ST	Q13546	RIPK1	Q13546	RIPK1	S166	A160S	160	Missense	distal	-6	no	6.739	7.058	EPSD;PhosphoSitePlus	ICGC	2.812	Up-regulation
TKL_RIPK_RIPK1_ST	Q13546	RIPK1	Q13546	RIPK1	S166	M164I	164	Missense	proximal	-2	no	6.739	6.557	EPSD;PhosphoSitePlus	ICGC	2.812	Down-regulation
TKL_RIPK_RIPK1_ST	Q13546	RIPK1	Q13546	RIPK1	S357	E364D	364	Missense	distal	7	no	2.756	2.943	EPSD	ICGC	2.812	Gain
TKL_RIPK_RIPK1_ST	Q5VWQ8	DAB2IP	Q13546	RIPK1	S295	G292C	292	Missense	distal	-3	no	4.371	4.356	EPSD	ICGC;COSMIC	2.812	Down-regulation
CMGC_RCK_MAK_ICK_ST	P46379	BAG6	Q9UPZ9	ICK	T92	P95S	95	Missense	distal	3	no	2.939	3.022	EPSD	ICGC	2.314	Up-regulation
CMGC_RCK_MAK_ICK_ST	P46379	BAG6	Q9UPZ9	ICK	T92	P90S	90	Missense	proximal	-2	no	2.939	-0.049	EPSD	ICGC;COSMIC	2.314	Loss
CMGC_RCK_MAK_ICK_ST	P46379	BAG6	Q9UPZ9	ICK	T92	R87Q	87	Missense	distal	-5	no	2.939	2.863	EPSD	ICGC	2.314	Down-regulation
CMGC_RCK_MAK_ICK_ST	P46379	BAG6	Q9UPZ9	ICK	T92	P95T	95	Missense	distal	3	no	2.939	3.024	EPSD	ICGC	2.314	Up-regulation
CMGC_RCK_MAK_ICK_ST	P46379	BAG6	Q9UPZ9	ICK	T185	Y188D	188	Missense	distal	3	no	3.936	3.943	EPSD	ICGC	2.314	Up-regulation
CMGC_RCK_MAK_ICK_ST	Q8N122	RPTOR	Q9UPZ9	ICK	T699	T699M	699	Missense	central	0	yes	4.331	0.000	EPSD	ICGC;COSMIC	2.314	Loss
CMGC_RCK_MAK_ICK_ST	Q8N122	RPTOR	Q9UPZ9	ICK	S791	D785Y	785	Missense	distal	-6	no	4.211	4.200	EPSD	ICGC	2.314	Down-regulation
CMGC_RCK_MAK_ICK_ST	Q8N122	RPTOR	Q9UPZ9	ICK	S792	D785Y	785	Missense	distal	-7	no	2.566	2.594	EPSD	ICGC	2.314	Up-regulation
CMGC_RCK_MAK_ICK_ST	Q8N122	RPTOR	Q9UPZ9	ICK	S881	S887N	887	Missense	distal	6	no	3.920	3.878	EPSD	ICGC;COSMIC	2.314	Down-regulation
CMGC_RCK_MAK_ICK_ST	Q8N122	RPTOR	Q9UPZ9	ICK	T908	A914V	914	Missense	distal	6	no	10.816	10.797	PhosphoSitePlus	ICGC;COSMIC	2.314	Down-regulation
CMGC_RCK_MAK_ICK_ST	Q8N122	RPTOR	Q9UPZ9	ICK	S920	A914V	914	Missense	distal	-6	no	2.681	2.654	EPSD	ICGC;COSMIC	2.314	Down-regulation
STE_STE20_YSK_STK24_ST	Q8TAE6	PPP1R14C	Q9Y6E0	STK24	T73	K75R	75	Missense	proximal	2	no	7.475	7.121	PhosphoSitePlus	ICGC	2.432	Down-regulation
STE_STE20_YSK_STK24_ST	Q8TAE6	PPP1R14C	Q9Y6E0	STK24	T73	G70V	70	Missense	distal	-3	no	7.475	7.107	PhosphoSitePlus	ICGC	2.432	Down-regulation
STE_STE20_YSK_STK24_ST	Q8TAE6	PPP1R14C	Q9Y6E0	STK24	T73	V74A	74	Missense	proximal	1	no	7.475	7.462	PhosphoSitePlus	ICGC	2.432	Down-regulation
STE_STE20_YSK_STK24_ST	Q9Y2H1	STK38L	Q9Y6E0	STK24	T8	T4M	4	Missense	distal	-4	no	3.132	3.141	EPSD	ICGC;COSMIC;CCLE	2.432	Up-regulation
STE_STE20_YSK_STK24_ST	Q9Y2H1	STK38L	Q9Y6E0	STK24	T8	P12S	12	Missense	distal	4	no	3.132	3.153	EPSD	ICGC	2.432	Up-regulation
STE_STE20_YSK_STK24_ST	Q9Y2H1	STK38L	Q9Y6E0	STK24	T8	P12H	12	Missense	distal	4	no	3.132	3.161	EPSD	ICGC;COSMIC	2.432	Up-regulation
STE_STE20_YSK_STK24_ST	Q9Y2H1	STK38L	Q9Y6E0	STK24	T442	W436C	436	Missense	distal	-6	no	8.532	8.526	PhosphoSitePlus	ICGC	2.432	Down-regulation
STE_STE20_YSK_STK24_ST	Q7L7X3	TAOK1	Q9Y6E0	STK24	S60	K57R	57	Missense	distal	-3	no	3.171	3.055	EPSD	ICGC;COSMIC	2.432	Down-regulation
STE_STE20_YSK_STK24_ST	Q7L7X3	TAOK1	Q9Y6E0	STK24	S575	K578Q	578	Missense	distal	3	no	3.421	3.527	EPSD	ICGC	2.432	Up-regulation
STE_STE20_YSK_STK24_ST	Q7L7X3	TAOK1	Q9Y6E0	STK24	S575	Q574H	574	Missense	proximal	-1	no	3.421	3.449	EPSD	ICGC;COSMIC	2.432	Up-regulation
STE_STE20_YSK_STK24_ST	Q7L7X3	TAOK1	Q9Y6E0	STK24	S717	K713N	713	Missense	distal	-4	no	3.033	3.047	EPSD	ICGC;COSMIC	2.432	Up-regulation
STE_STE20_YSK_STK24_ST	Q7L7X3	TAOK1	Q9Y6E0	STK24	S717	L715F	715	Missense	proximal	-2	no	3.033	3.029	EPSD	ICGC;COSMIC	2.432	Down-regulation
CMGC_DYRK_DYRK2_DYRK2_ST	Q13541	EIF4EBP1	Q92630	DYRK2	S2	C7S	7	Missense	distal	5	no	62.433	60.658	EPSD	ICGC;COSMIC	45.963	Down-regulation
CMGC_DYRK_DYRK2_DYRK2_ST	Q13541	EIF4EBP1	Q92630	DYRK2	T10	C7S	7	Missense	distal	-3	no	69.914	63.346	EPSD	ICGC;COSMIC	45.963	Down-regulation
CMGC_DYRK_DYRK2_DYRK2_ST	Q13541	EIF4EBP1	Q92630	DYRK2	T37	G40V	40	Missense	distal	3	no	52.143	52.157	EPSD	ICGC;COSMIC	45.963	Up-regulation
CMGC_DYRK_DYRK2_DYRK2_ST	Q13541	EIF4EBP1	Q92630	DYRK2	T37	S35I	35	Missense	proximal	-2	no	52.143	47.694	EPSD	ICGC	45.963	Down-regulation
CMGC_DYRK_DYRK2_DYRK2_ST	Q13541	EIF4EBP1	Q92630	DYRK2	T37	T41S	41	Missense	distal	4	no	52.143	52.077	EPSD	ICGC;COSMIC	45.963	Down-regulation
CMGC_DYRK_DYRK2_DYRK2_ST	Q13541	EIF4EBP1	Q92630	DYRK2	S65	P71A	71	Missense	distal	6	no	82.988	82.748	PhosphoSitePlus;EPSD	ICGC;COSMIC	45.963	Down-regulation
CMGC_DYRK_DYRK2_DYRK2_ST	Q13541	EIF4EBP1	Q92630	DYRK2	S65	P71H	71	Missense	distal	6	no	82.988	82.342	PhosphoSitePlus;EPSD	ICGC;COSMIC	45.963	Down-regulation
CMGC_DYRK_DYRK2_DYRK2_ST	Q13541	EIF4EBP1	Q92630	DYRK2	T68	P71A	71	Missense	distal	3	no	47.168	44.286	EPSD	ICGC;COSMIC	45.963	Loss
CMGC_DYRK_DYRK2_DYRK2_ST	Q13541	EIF4EBP1	Q92630	DYRK2	T68	P71H	71	Missense	distal	3	no	47.168	43.954	EPSD	ICGC;COSMIC	45.963	Loss
CMGC_DYRK_DYRK2_DYRK2_ST	Q13541	EIF4EBP1	Q92630	DYRK2	T70	P71A	71	Missense	proximal	1	no	56.720	-15.773	EPSD	ICGC;COSMIC	45.963	Loss
CMGC_DYRK_DYRK2_DYRK2_ST	Q13541	EIF4EBP1	Q92630	DYRK2	T70	P71H	71	Missense	proximal	1	no	56.720	-52.509	EPSD	ICGC;COSMIC	45.963	Loss
CMGC_DYRK_DYRK2_DYRK2_ST	Q13541	EIF4EBP1	Q92630	DYRK2	S101	S94I	94	Missense	distal	-7	no	90.431	90.642	EPSD;PhosphoSitePlus	ICGC	45.963	Up-regulation
CMGC_DYRK_DYRK2_DYRK2_ST	Q13541	EIF4EBP1	Q92630	DYRK2	S101	R106Q	106	Missense	distal	5	no	90.431	89.645	EPSD;PhosphoSitePlus	ICGC;COSMIC	45.963	Down-regulation
CMGC_DYRK_DYRK2_DYRK2_ST	Q13541	EIF4EBP1	Q92630	DYRK2	S101	G108C	108	Missense	distal	7	no	90.431	91.875	EPSD;PhosphoSitePlus	ICGC;COSMIC	45.963	Up-regulation
CMGC_DYRK_DYRK2_DYRK2_ST	Q13541	EIF4EBP1	Q92630	DYRK2	S101	A107T	107	Missense	distal	6	no	90.431	90.637	EPSD;PhosphoSitePlus	ICGC;COSMIC	45.963	Up-regulation
CMGC_DYRK_DYRK2_DYRK2_ST	Q13541	EIF4EBP1	Q92630	DYRK2	S101	D104Y	104	Missense	distal	3	no	90.431	89.141	EPSD;PhosphoSitePlus	ICGC;COSMIC	45.963	Down-regulation
CMGC_DYRK_DYRK2_DYRK2_ST	Q13541	EIF4EBP1	Q92630	DYRK2	S101	H97Q	97	Missense	distal	-4	no	90.431	97.119	EPSD;PhosphoSitePlus	ICGC;COSMIC	45.963	Up-regulation
CMGC_DYRK_DYRK2_DYRK2_ST	Q13541	EIF4EBP1	Q92630	DYRK2	S101	S101C	101	Missense	central	0	yes	90.431	0.000	EPSD;PhosphoSitePlus	ICGC;COSMIC	45.963	Loss
CMGC_DYRK_DYRK2_DYRK2_ST	O43255	SIAH2	Q92630	DYRK2	T119	T113K	113	Missense	distal	-6	no	81.768	81.740	EPSD;PhosphoSitePlus	ICGC	45.963	Down-regulation
CMGC_DYRK_DYRK2_DYRK2_ST	O43255	SIAH2	Q92630	DYRK2	T119	L118M	118	Missense	proximal	-1	no	81.768	80.947	EPSD;PhosphoSitePlus	ICGC;COSMIC	45.963	Down-regulation
CMGC_DYRK_DYRK2_DYRK2_ST	O43255	SIAH2	Q92630	DYRK2	T119	I122T	122	Missense	distal	3	no	81.768	82.727	EPSD;PhosphoSitePlus	ICGC	45.963	Up-regulation
CMGC_DYRK_DYRK2_DYRK2_ST	O43255	SIAH2	Q92630	DYRK2	T119	A126D	126	Missense	distal	7	no	81.768	84.071	EPSD;PhosphoSitePlus	ICGC;COSMIC	45.963	Up-regulation
CMGC_DYRK_DYRK2_DYRK2_ST	Q9Y2V2	CARHSP1	Q92630	DYRK2	S17	G19W	19	Missense	proximal	2	no	47.111	47.480	EPSD	ICGC;COSMIC	45.963	Up-regulation
CMGC_DYRK_DYRK2_DYRK2_ST	Q9Y2V2	CARHSP1	Q92630	DYRK2	T23	G19W	19	Missense	distal	-4	no	48.159	52.470	EPSD	ICGC;COSMIC	45.963	Up-regulation
CMGC_DYRK_DYRK2_DYRK2_ST	Q9Y2V2	CARHSP1	Q92630	DYRK2	S41	P44H	44	Missense	distal	3	no	79.293	76.079	PhosphoSitePlus;EPSD	ICGC;COSMIC	45.963	Down-regulation
CMGC_DYRK_DYRK2_DYRK2_ST	Q9Y2V2	CARHSP1	Q92630	DYRK2	T54	S52L	52	Missense	proximal	-2	no	48.708	44.334	EPSD	ICGC;COSMIC	45.963	Loss
CMGC_DYRK_DYRK2_DYRK2_ST	Q9Y2V2	CARHSP1	Q92630	DYRK2	T80	F78V	78	Missense	proximal	-2	no	52.728	65.381	EPSD	ICGC;COSMIC	45.963	Up-regulation
CMGC_DYRK_DYRK2_DYRK2_ST	Q9Y2V2	CARHSP1	Q92630	DYRK2	S141	W140L	140	Missense	proximal	-1	no	54.435	55.244	EPSD	ICGC;COSMIC	45.963	Up-regulation
CMGC_DYRK_DYRK2_DYRK2_ST	O43602	DCX	Q92630	DYRK2	S310	Q314R	314	Missense	distal	4	no	47.527	47.559	EPSD	ICGC	45.963	Up-regulation
CMGC_DYRK_DYRK2_DYRK2_ST	O75449	KATNA1	Q92630	DYRK2	S42	Q35K	35	Missense	distal	-7	no	72.376	71.830	PhosphoSitePlus;EPSD	ICGC	45.963	Down-regulation
CMGC_DYRK_DYRK2_DYRK2_ST	O75449	KATNA1	Q92630	DYRK2	T81	H88N	88	Missense	distal	7	no	45.371	51.888	EPSD	ICGC	45.963	Gain
CMGC_DYRK_DYRK2_DYRK2_ST	O75449	KATNA1	Q92630	DYRK2	T81	H88R	88	Missense	distal	7	no	45.371	50.492	EPSD	ICGC;COSMIC	45.963	Gain
CMGC_DYRK_DYRK2_DYRK2_ST	O75449	KATNA1	Q92630	DYRK2	S109	P110T	110	Missense	proximal	1	no	90.013	67.938	EPSD;PhosphoSitePlus	ICGC	45.963	Down-regulation
CMGC_DYRK_DYRK2_DYRK2_ST	O75449	KATNA1	Q92630	DYRK2	S109	R115C	115	Missense	distal	6	no	90.013	90.388	EPSD;PhosphoSitePlus	ICGC	45.963	Up-regulation
CMGC_DYRK_DYRK2_DYRK2_ST	O75449	KATNA1	Q92630	DYRK2	S109	R113I	113	Missense	distal	4	no	90.013	89.904	EPSD;PhosphoSitePlus	ICGC;COSMIC	45.963	Down-regulation
CMGC_DYRK_DYRK2_DYRK2_ST	O75449	KATNA1	Q92630	DYRK2	T133	R138H	138	Missense	distal	5	no	72.220	68.822	EPSD;PhosphoSitePlus	ICGC;COSMIC	45.963	Down-regulation
CMGC_DYRK_DYRK2_DYRK2_ST	O75449	KATNA1	Q92630	DYRK2	S170	A173T	173	Missense	distal	3	no	57.555	59.864	EPSD	ICGC	45.963	Up-regulation
CMGC_DYRK_DYRK2_DYRK2_ST	O75449	KATNA1	Q92630	DYRK2	S170	S170L	170	Missense	central	0	yes	57.555	0.000	EPSD	ICGC;COSMIC	45.963	Loss
CMGC_DYRK_DYRK2_DYRK2_ST	O75449	KATNA1	Q92630	DYRK2	T441	T441P	441	Missense	central	0	yes	47.492	0.000	EPSD	ICGC;COSMIC	45.963	Loss
CMGC_DYRK_DYRK2_DYRK2_ST	P04637	TP53	Q92630	DYRK2	S9	E11K	11	Missense	proximal	2	no	56.920	57.179	EPSD	ICGC;COSMIC	45.963	Up-regulation
CMGC_DYRK_DYRK2_DYRK2_ST	P04637	TP53	Q92630	DYRK2	S33	P34L	34	Missense	proximal	1	no	50.772	2.558	EPSD	ICGC;COSMIC	45.963	Loss
CMGC_DYRK_DYRK2_DYRK2_ST	P04637	TP53	Q92630	DYRK2	S33	S33F	33	Missense	central	0	yes	50.772	0.000	EPSD	ICGC;COSMIC	45.963	Loss
CMGC_DYRK_DYRK2_DYRK2_ST	P04637	TP53	Q92630	DYRK2	S33	N30I	30	Missense	distal	-3	no	50.772	44.346	EPSD	ICGC	45.963	Loss
CMGC_DYRK_DYRK2_DYRK2_ST	P04637	TP53	Q92630	DYRK2	S46	D48G	48	Missense	proximal	2	no	78.736	78.270	PhosphoSitePlus	ICGC;COSMIC	45.963	Down-regulation
CMGC_DYRK_DYRK2_DYRK2_ST	P04637	TP53	Q92630	DYRK2	S46	Q52K	52	Missense	distal	6	no	78.736	78.583	PhosphoSitePlus	ICGC	45.963	Down-regulation
CMGC_DYRK_DYRK2_DYRK2_ST	P04637	TP53	Q92630	DYRK2	T81	A88D	88	Missense	distal	7	no	57.238	59.540	EPSD	ICGC	45.963	Up-regulation
CMGC_DYRK_DYRK2_DYRK2_ST	P04637	TP53	Q92630	DYRK2	T81	P87Q	87	Missense	distal	6	no	57.238	57.387	EPSD	ICGC;COSMIC	45.963	Up-regulation
CMGC_DYRK_DYRK2_DYRK2_ST	P04637	TP53	Q92630	DYRK2	S99	Q100K	100	Missense	proximal	1	no	29.268	57.945	EPSD	ICGC;COSMIC	45.963	Gain
CMGC_DYRK_DYRK2_DYRK2_ST	P04637	TP53	Q92630	DYRK2	S127	T125R	125	Missense	proximal	-2	no	37.162	47.769	EPSD	ICGC;COSMIC	45.963	Gain
CMGC_DYRK_DYRK2_DYRK2_ST	P04637	TP53	Q92630	DYRK2	S127	C124R	124	Missense	distal	-3	no	37.162	46.504	EPSD	ICGC;COSMIC;GDSC;CCLE	45.963	Gain
CMGC_DYRK_DYRK2_DYRK2_ST	P04637	TP53	Q92630	DYRK2	S149	L145Q	145	Missense	distal	-4	no	41.068	49.743	EPSD	ICGC;COSMIC	45.963	Gain
CMGC_DYRK_DYRK2_DYRK2_ST	P04637	TP53	Q92630	DYRK2	T150	R156L	156	Missense	distal	6	no	53.573	53.309	EPSD	ICGC;COSMIC	45.963	Down-regulation
CMGC_DYRK_DYRK2_DYRK2_ST	P04637	TP53	Q92630	DYRK2	T150	L145Q	145	Missense	distal	-5	no	53.573	52.706	EPSD	ICGC;COSMIC	45.963	Down-regulation
CMGC_DYRK_DYRK2_DYRK2_ST	P04637	TP53	Q92630	DYRK2	T150	P152R	152	Missense	proximal	2	no	53.573	53.698	EPSD	ICGC;COSMIC	45.963	Up-regulation
CMGC_DYRK_DYRK2_DYRK2_ST	P04637	TP53	Q92630	DYRK2	T150	G154S	154	Missense	distal	4	no	53.573	53.603	EPSD	ICGC;COSMIC	45.963	Up-regulation
CMGC_DYRK_DYRK2_DYRK2_ST	P04637	TP53	Q92630	DYRK2	T150	V157A	157	Missense	distal	7	no	53.573	50.697	EPSD	ICGC;COSMIC	45.963	Down-regulation
CMGC_DYRK_DYRK2_DYRK2_ST	P04637	TP53	Q92630	DYRK2	T150	P151F	151	Missense	proximal	1	no	53.573	-8.124	EPSD	ICGC;COSMIC	45.963	Loss
CMGC_DYRK_DYRK2_DYRK2_ST	P04637	TP53	Q92630	DYRK2	T150	V147G	147	Missense	distal	-3	no	53.573	53.377	EPSD	ICGC;COSMIC;GDSC;CCLE	45.963	Down-regulation
CMGC_DYRK_DYRK2_DYRK2_ST	P04637	TP53	Q92630	DYRK2	T211	F212V	212	Missense	proximal	1	no	10.979	64.645	EPSD	ICGC;COSMIC	45.963	Gain
CMGC_DYRK_DYRK2_DYRK2_ST	P04637	TP53	Q92630	DYRK2	S215	P219T	219	Missense	distal	4	no	56.176	56.111	EPSD	ICGC;COSMIC	45.963	Down-regulation
CMGC_DYRK_DYRK2_DYRK2_ST	P04637	TP53	Q92630	DYRK2	S215	H214D	214	Missense	proximal	-1	no	56.176	53.966	EPSD	ICGC;COSMIC	45.963	Down-regulation
CMGC_DYRK_DYRK2_DYRK2_ST	P04637	TP53	Q92630	DYRK2	S215	Y220N	220	Missense	distal	5	no	56.176	57.066	EPSD	ICGC;COSMIC	45.963	Up-regulation
CMGC_DYRK_DYRK2_DYRK2_ST	P04637	TP53	Q92630	DYRK2	S215	E221V	221	Missense	distal	6	no	56.176	56.705	EPSD	ICGC;COSMIC	45.963	Up-regulation
CMGC_DYRK_DYRK2_DYRK2_ST	P04637	TP53	Q92630	DYRK2	S215	E221K	221	Missense	distal	6	no	56.176	56.547	EPSD	ICGC;COSMIC	45.963	Up-regulation
CMGC_DYRK_DYRK2_DYRK2_ST	P04637	TP53	Q92630	DYRK2	S215	H214Y	214	Missense	proximal	-1	no	56.176	54.830	EPSD	ICGC;COSMIC	45.963	Down-regulation
CMGC_DYRK_DYRK2_DYRK2_ST	P04637	TP53	Q92630	DYRK2	S215	T211P	211	Missense	distal	-4	no	56.176	59.447	EPSD	ICGC;COSMIC	45.963	Up-regulation
CMGC_DYRK_DYRK2_DYRK2_ST	P04637	TP53	Q92630	DYRK2	S215	F212V	212	Missense	distal	-3	no	56.176	61.526	EPSD	ICGC;COSMIC	45.963	Up-regulation
CMGC_DYRK_DYRK2_DYRK2_ST	P04637	TP53	Q92630	DYRK2	S215	D208V	208	Missense	distal	-7	no	56.176	56.597	EPSD	ICGC;COSMIC	45.963	Up-regulation
CMGC_DYRK_DYRK2_DYRK2_ST	P04637	TP53	Q92630	DYRK2	S215	V217G	217	Missense	proximal	2	no	56.176	55.724	EPSD	ICGC;COSMIC;CCLE	45.963	Down-regulation
CMGC_DYRK_DYRK2_DYRK2_ST	P04637	TP53	Q92630	DYRK2	S313	T312I	312	Missense	proximal	-1	no	47.453	48.867	EPSD	ICGC;COSMIC	45.963	Up-regulation
CMGC_DYRK_DYRK2_DYRK2_ST	P04637	TP53	Q92630	DYRK2	S315	T312I	312	Missense	distal	-3	no	59.350	57.034	EPSD	ICGC;COSMIC	45.963	Down-regulation
CMGC_DYRK_DYRK2_DYRK2_ST	P04637	TP53	Q92630	DYRK2	S315	P322T	322	Missense	distal	7	no	59.350	58.098	EPSD	ICGC	45.963	Down-regulation
CMGC_DYRK_DYRK2_DYRK2_ST	P04637	TP53	Q92630	DYRK2	S376	T377P	377	Missense	proximal	1	no	35.344	57.419	EPSD	ICGC;COSMIC	45.963	Gain
CMGC_DYRK_DYRK2_DYRK2_ST	Q14195	DPYSL3	Q92630	DYRK2	S257	A260E	260	Missense	distal	3	no	46.949	47.279	EPSD	ICGC;COSMIC	45.963	Up-regulation
CMGC_DYRK_DYRK2_DYRK2_ST	Q14195	DPYSL3	Q92630	DYRK2	S257	V255F	255	Missense	proximal	-2	no	46.949	34.296	EPSD	ICGC;COSMIC	45.963	Loss
CMGC_DYRK_DYRK2_DYRK2_ST	Q14195	DPYSL3	Q92630	DYRK2	S304	A298V	298	Missense	distal	-6	no	59.586	59.348	EPSD	ICGC;COSMIC	45.963	Down-regulation
CMGC_DYRK_DYRK2_DYRK2_ST	Q14195	DPYSL3	Q92630	DYRK2	S304	V302L	302	Missense	proximal	-2	no	59.586	53.656	EPSD	ICGC;COSMIC	45.963	Down-regulation
CMGC_DYRK_DYRK2_DYRK2_ST	Q14195	DPYSL3	Q92630	DYRK2	S304	P306L	306	Missense	proximal	2	no	59.586	58.624	EPSD	ICGC	45.963	Down-regulation
CMGC_DYRK_DYRK2_DYRK2_ST	Q14195	DPYSL3	Q92630	DYRK2	S304	A300T	300	Missense	distal	-4	no	59.586	56.876	EPSD	ICGC;COSMIC	45.963	Down-regulation
CMGC_DYRK_DYRK2_DYRK2_ST	Q14195	DPYSL3	Q92630	DYRK2	S304	V302A	302	Missense	proximal	-2	no	59.586	55.875	EPSD	ICGC	45.963	Down-regulation
CMGC_DYRK_DYRK2_DYRK2_ST	Q14195	DPYSL3	Q92630	DYRK2	S363	I365M	365	Missense	proximal	2	no	61.818	62.250	EPSD	ICGC;COSMIC	45.963	Up-regulation
CMGC_DYRK_DYRK2_DYRK2_ST	Q14195	DPYSL3	Q92630	DYRK2	S363	R361W	361	Missense	proximal	-2	no	61.818	52.048	EPSD	ICGC;COSMIC	45.963	Down-regulation
CMGC_DYRK_DYRK2_DYRK2_ST	Q14195	DPYSL3	Q92630	DYRK2	S363	M362L	362	Missense	proximal	-1	no	61.818	62.639	EPSD	ICGC;COSMIC	45.963	Up-regulation
CMGC_DYRK_DYRK2_DYRK2_ST	Q14195	DPYSL3	Q92630	DYRK2	S363	E359V	359	Missense	distal	-4	no	61.818	60.015	EPSD	ICGC;COSMIC	45.963	Down-regulation
CMGC_DYRK_DYRK2_DYRK2_ST	Q14195	DPYSL3	Q92630	DYRK2	S363	K368N	368	Missense	distal	5	no	61.818	63.709	EPSD	ICGC;COSMIC	45.963	Up-regulation
CMGC_DYRK_DYRK2_DYRK2_ST	Q14195	DPYSL3	Q92630	DYRK2	S402	R397H	397	Missense	distal	-5	no	46.800	48.222	EPSD	ICGC;COSMIC	45.963	Up-regulation
CMGC_DYRK_DYRK2_DYRK2_ST	Q14195	DPYSL3	Q92630	DYRK2	S402	R397C	397	Missense	distal	-5	no	46.800	46.759	EPSD	ICGC;COSMIC	45.963	Down-regulation
CMGC_DYRK_DYRK2_DYRK2_ST	Q14195	DPYSL3	Q92630	DYRK2	S402	S407N	407	Missense	distal	5	no	46.800	48.312	EPSD	ICGC;COSMIC	45.963	Up-regulation
CMGC_DYRK_DYRK2_DYRK2_ST	Q14195	DPYSL3	Q92630	DYRK2	S402	P396H	396	Missense	distal	-6	no	46.800	47.236	EPSD	ICGC	45.963	Up-regulation
CMGC_DYRK_DYRK2_DYRK2_ST	Q14195	DPYSL3	Q92630	DYRK2	S402	P396S	396	Missense	distal	-6	no	46.800	46.952	EPSD	ICGC;COSMIC	45.963	Up-regulation
CMGC_DYRK_DYRK2_DYRK2_ST	Q14195	DPYSL3	Q92630	DYRK2	S402	G399R	399	Missense	distal	-3	no	46.800	65.313	EPSD	ICGC;COSMIC	45.963	Up-regulation
CMGC_DYRK_DYRK2_DYRK2_ST	Q14195	DPYSL3	Q92630	DYRK2	S402	D408N	408	Missense	distal	6	no	46.800	47.096	EPSD	ICGC;COSMIC	45.963	Up-regulation
CMGC_DYRK_DYRK2_DYRK2_ST	Q14195	DPYSL3	Q92630	DYRK2	S402	R400I	400	Missense	proximal	-2	no	46.800	34.210	EPSD	ICGC;COSMIC	45.963	Loss
CMGC_DYRK_DYRK2_DYRK2_ST	Q14195	DPYSL3	Q92630	DYRK2	T509	A516E	516	Missense	distal	7	no	56.305	54.354	EPSD	ICGC;COSMIC	45.963	Down-regulation
CMGC_DYRK_DYRK2_DYRK2_ST	Q14195	DPYSL3	Q92630	DYRK2	T509	T509N	509	Missense	central	0	yes	56.305	0.000	EPSD	ICGC;COSMIC	45.963	Loss
CMGC_DYRK_DYRK2_DYRK2_ST	Q14195	DPYSL3	Q92630	DYRK2	T509	P502L	502	Missense	distal	-7	no	56.305	54.585	EPSD	ICGC;COSMIC	45.963	Down-regulation
CMGC_DYRK_DYRK2_DYRK2_ST	Q14195	DPYSL3	Q92630	DYRK2	T509	T507I	507	Missense	proximal	-2	no	56.305	54.322	EPSD	ICGC;COSMIC	45.963	Down-regulation
CMGC_DYRK_DYRK2_DYRK2_ST	Q14195	DPYSL3	Q92630	DYRK2	T514	R520W	520	Missense	distal	6	no	52.124	52.150	EPSD	ICGC;COSMIC	45.963	Up-regulation
CMGC_DYRK_DYRK2_DYRK2_ST	Q14195	DPYSL3	Q92630	DYRK2	T514	A516E	516	Missense	proximal	2	no	52.124	51.996	EPSD	ICGC;COSMIC	45.963	Down-regulation
CMGC_DYRK_DYRK2_DYRK2_ST	Q14195	DPYSL3	Q92630	DYRK2	T514	T509N	509	Missense	distal	-5	no	52.124	53.089	EPSD	ICGC;COSMIC	45.963	Up-regulation
CMGC_DYRK_DYRK2_DYRK2_ST	Q14195	DPYSL3	Q92630	DYRK2	T514	T507I	507	Missense	distal	-7	no	52.124	51.234	EPSD	ICGC;COSMIC	45.963	Down-regulation
CMGC_DYRK_DYRK2_DYRK2_ST	Q14195	DPYSL3	Q92630	DYRK2	S522	R520W	520	Missense	proximal	-2	no	87.074	77.303	PhosphoSitePlus	ICGC;COSMIC	45.963	Down-regulation
CMGC_DYRK_DYRK2_DYRK2_ST	Q14195	DPYSL3	Q92630	DYRK2	S522	P526L	526	Missense	distal	4	no	87.074	86.859	PhosphoSitePlus	ICGC;COSMIC	45.963	Down-regulation
CMGC_DYRK_DYRK2_DYRK2_ST	Q14195	DPYSL3	Q92630	DYRK2	S522	A516E	516	Missense	distal	-6	no	87.074	87.136	PhosphoSitePlus	ICGC;COSMIC	45.963	Up-regulation
CMGC_DYRK_DYRK2_DYRK2_ST	Q14195	DPYSL3	Q92630	DYRK2	S522	P528T	528	Missense	distal	6	no	87.074	87.040	PhosphoSitePlus	ICGC	45.963	Down-regulation
CMGC_DYRK_DYRK2_DYRK2_ST	Q14195	DPYSL3	Q92630	DYRK2	S522	S522F	522	Missense	central	0	yes	87.074	0.000	PhosphoSitePlus	ICGC	45.963	Loss
CMGC_DYRK_DYRK2_DYRK2_ST	Q14195	DPYSL3	Q92630	DYRK2	S553	R555H	555	Missense	proximal	2	no	62.987	62.075	EPSD	ICGC;COSMIC	45.963	Down-regulation
CMGC_DYRK_DYRK2_DYRK2_ST	Q14195	DPYSL3	Q92630	DYRK2	S553	A558V	558	Missense	distal	5	no	62.987	62.374	EPSD	ICGC;COSMIC	45.963	Down-regulation
CMGC_DYRK_DYRK2_DYRK2_ST	Q14195	DPYSL3	Q92630	DYRK2	T567	R563H	563	Missense	distal	-4	no	59.421	51.987	EPSD	ICGC	45.963	Down-regulation
CMGC_DYRK_DYRK2_DYRK2_ST	Q14195	DPYSL3	Q92630	DYRK2	T567	R563L	563	Missense	distal	-4	no	59.421	49.999	EPSD	ICGC;COSMIC	45.963	Down-regulation
CMGC_DYRK_DYRK2_DYRK2_ST	Q14195	DPYSL3	Q92630	DYRK2	T567	G562S	562	Missense	distal	-5	no	59.421	59.024	EPSD	ICGC;COSMIC	45.963	Down-regulation
CMGC_DYRK_DYRK2_DYRK2_ST	Q14195	DPYSL3	Q92630	DYRK2	T567	I566M	566	Missense	proximal	-1	no	59.421	58.782	EPSD	ICGC;COSMIC	45.963	Down-regulation
CMGC_DYRK_DYRK2_DYRK2_ST	Q16555	DPYSL2	Q92630	DYRK2	S304	D310G	310	Missense	distal	6	no	55.536	55.418	EPSD	ICGC;COSMIC	45.963	Down-regulation
CMGC_DYRK_DYRK2_DYRK2_ST	Q16555	DPYSL2	Q92630	DYRK2	S308	D310G	310	Missense	proximal	2	no	47.734	47.268	EPSD	ICGC;COSMIC	45.963	Down-regulation
CMGC_DYRK_DYRK2_DYRK2_ST	Q16555	DPYSL2	Q92630	DYRK2	S363	R361W	361	Missense	proximal	-2	no	52.089	42.319	EPSD	ICGC;COSMIC	45.963	Loss
CMGC_DYRK_DYRK2_DYRK2_ST	Q16555	DPYSL2	Q92630	DYRK2	T509	P515L	515	Missense	distal	6	no	56.167	55.682	EPSD	ICGC	45.963	Down-regulation
CMGC_DYRK_DYRK2_DYRK2_ST	Q16555	DPYSL2	Q92630	DYRK2	T512	P515L	515	Missense	distal	3	no	58.024	56.252	EPSD	ICGC	45.963	Down-regulation
CMGC_DYRK_DYRK2_DYRK2_ST	Q16555	DPYSL2	Q92630	DYRK2	T514	P515L	515	Missense	proximal	1	no	61.228	13.013	EPSD	ICGC	45.963	Loss
CMGC_DYRK_DYRK2_DYRK2_ST	Q16555	DPYSL2	Q92630	DYRK2	S522	P515L	515	Missense	distal	-7	no	81.328	79.608	PhosphoSitePlus	ICGC	45.963	Down-regulation
CMGC_DYRK_DYRK2_DYRK2_ST	P10636	MAPT	Q92630	DYRK2	S214	G208C	208	Missense	distal	-6	no	65.937	65.540	EPSD	ICGC;COSMIC	45.963	Down-regulation
CMGC_DYRK_DYRK2_DYRK2_ST	P10636	MAPT	Q92630	DYRK2	S214	R211S	211	Missense	distal	-3	no	65.937	50.027	EPSD	ICGC;COSMIC	45.963	Down-regulation
CMGC_DYRK_DYRK2_DYRK2_ST	P10636	MAPT	Q92630	DYRK2	S214	G213E	213	Missense	proximal	-1	no	65.937	66.188	EPSD	ICGC;COSMIC	45.963	Up-regulation
CMGC_DYRK_DYRK2_DYRK2_ST	P10636	MAPT	Q92630	DYRK2	S235	P233H	233	Missense	proximal	-2	no	48.540	35.187	EPSD	ICGC;COSMIC	45.963	Loss
CMGC_DYRK_DYRK2_DYRK2_ST	P10636	MAPT	Q92630	DYRK2	S235	S232F	232	Missense	distal	-3	no	48.540	40.784	EPSD	ICGC	45.963	Loss
CMGC_DYRK_DYRK2_DYRK2_ST	P10636	MAPT	Q92630	DYRK2	S235	P239Q	239	Missense	distal	4	no	48.540	48.484	EPSD	ICGC;COSMIC	45.963	Down-regulation
CMGC_DYRK_DYRK2_DYRK2_ST	P10636	MAPT	Q92630	DYRK2	S238	P233H	233	Missense	distal	-5	no	53.612	55.544	EPSD	ICGC;COSMIC	45.963	Up-regulation
CMGC_DYRK_DYRK2_DYRK2_ST	P10636	MAPT	Q92630	DYRK2	S238	S232F	232	Missense	distal	-6	no	53.612	53.830	EPSD	ICGC	45.963	Up-regulation
CMGC_DYRK_DYRK2_DYRK2_ST	P10636	MAPT	Q92630	DYRK2	S238	P239Q	239	Missense	proximal	1	no	53.612	8.738	EPSD	ICGC;COSMIC	45.963	Loss
CMGC_DYRK_DYRK2_DYRK2_ST	P10636	MAPT	Q92630	DYRK2	S428	S427F	427	Missense	proximal	-1	no	64.641	65.850	EPSD	ICGC	45.963	Up-regulation
CMGC_DYRK_DYRK2_DYRK2_ST	P10636	MAPT	Q92630	DYRK2	S438	Y441H	441	Missense	distal	3	no	65.359	63.941	EPSD	ICGC;COSMIC	45.963	Down-regulation
CMGC_DYRK_DYRK2_DYRK2_ST	P10636	MAPT	Q92630	DYRK2	S519	G521R	521	Missense	proximal	2	no	57.632	58.475	EPSD	ICGC;COSMIC	45.963	Up-regulation
CMGC_DYRK_DYRK2_DYRK2_ST	P10636	MAPT	Q92630	DYRK2	T522	G521R	521	Missense	proximal	-1	no	60.523	59.338	EPSD	ICGC;COSMIC	45.963	Down-regulation
CMGC_DYRK_DYRK2_DYRK2_ST	P43686	PSMC4	Q92630	DYRK2	T25	G26S	26	Missense	proximal	1	no	64.572	56.356	PhosphoSitePlus	ICGC;COSMIC	45.963	Down-regulation
CMGC_DYRK_DYRK2_DYRK2_ST	Q9UHD2	TBK1	Q92630	DYRK2	S151	E147K	147	Missense	distal	-4	no	46.876	47.845	EPSD	ICGC;COSMIC	45.963	Up-regulation
CMGC_DYRK_DYRK2_DYRK2_ST	Q9UHD2	TBK1	Q92630	DYRK2	S151	Q150H	150	Missense	proximal	-1	no	46.876	49.839	EPSD	ICGC;COSMIC	45.963	Up-regulation
CMGC_DYRK_DYRK2_DYRK2_ST	Q9UHD2	TBK1	Q92630	DYRK2	S151	D148H	148	Missense	distal	-3	no	46.876	38.577	EPSD	ICGC;COSMIC	45.963	Loss
CMGC_DYRK_DYRK2_DYRK2_ST	Q9UHD2	TBK1	Q92630	DYRK2	T278	G272S	272	Missense	distal	-6	no	46.639	46.631	EPSD	ICGC;COSMIC	45.963	Down-regulation
CMGC_DYRK_DYRK2_DYRK2_ST	Q9UHD2	TBK1	Q92630	DYRK2	S527	D523N	523	Missense	distal	-4	no	80.649	80.535	PhosphoSitePlus	ICGC;COSMIC	45.963	Down-regulation
CMGC_DYRK_DYRK2_DYRK2_ST	Q9UHD2	TBK1	Q92630	DYRK2	S527	R525S	525	Missense	proximal	-2	no	80.649	72.508	PhosphoSitePlus	ICGC;COSMIC	45.963	Down-regulation
CMGC_DYRK_DYRK2_DYRK2_ST	Q9UHD2	TBK1	Q92630	DYRK2	T672	M673V	673	Missense	proximal	1	no	31.402	53.244	EPSD	ICGC;COSMIC	45.963	Gain
CMGC_DYRK_DYRK2_DYRK2_ST	Q9UHD2	TBK1	Q92630	DYRK2	T674	M673V	673	Missense	proximal	-1	no	59.959	60.308	EPSD	ICGC;COSMIC	45.963	Up-regulation
CMGC_DYRK_DYRK2_DYRK2_ST	Q14194	CRMP1	Q92630	DYRK2	S257	V250M	250	Missense	distal	-7	no	50.957	50.335	EPSD	ICGC;COSMIC	45.963	Down-regulation
CMGC_DYRK_DYRK2_DYRK2_ST	Q14194	CRMP1	Q92630	DYRK2	S257	D262N	262	Missense	distal	5	no	50.957	50.858	EPSD	ICGC;COSMIC	45.963	Down-regulation
CMGC_DYRK_DYRK2_DYRK2_ST	Q14194	CRMP1	Q92630	DYRK2	S257	K258R	258	Missense	proximal	1	no	50.957	10.763	EPSD	ICGC;COSMIC	45.963	Loss
CMGC_DYRK_DYRK2_DYRK2_ST	Q14194	CRMP1	Q92630	DYRK2	S257	S259R	259	Missense	proximal	2	no	50.957	51.595	EPSD	ICGC	45.963	Up-regulation
CMGC_DYRK_DYRK2_DYRK2_ST	Q14194	CRMP1	Q92630	DYRK2	S257	I263V	263	Missense	distal	6	no	50.957	51.497	EPSD	ICGC;COSMIC	45.963	Up-regulation
CMGC_DYRK_DYRK2_DYRK2_ST	Q14194	CRMP1	Q92630	DYRK2	S304	V302M	302	Missense	proximal	-2	no	57.122	58.190	EPSD	ICGC;COSMIC	45.963	Up-regulation
CMGC_DYRK_DYRK2_DYRK2_ST	Q14194	CRMP1	Q92630	DYRK2	S304	A300V	300	Missense	distal	-4	no	57.122	57.039	EPSD	ICGC;COSMIC	45.963	Down-regulation
CMGC_DYRK_DYRK2_DYRK2_ST	Q14194	CRMP1	Q92630	DYRK2	S304	S308N	308	Missense	distal	4	no	57.122	57.256	EPSD	ICGC;COSMIC	45.963	Up-regulation
CMGC_DYRK_DYRK2_DYRK2_ST	Q14194	CRMP1	Q92630	DYRK2	S304	A299E	299	Missense	distal	-5	no	57.122	57.181	EPSD	ICGC;COSMIC	45.963	Up-regulation
CMGC_DYRK_DYRK2_DYRK2_ST	Q14194	CRMP1	Q92630	DYRK2	S304	A299T	299	Missense	distal	-5	no	57.122	56.410	EPSD	ICGC;COSMIC	45.963	Down-regulation
CMGC_DYRK_DYRK2_DYRK2_ST	Q14194	CRMP1	Q92630	DYRK2	S304	A299V	299	Missense	distal	-5	no	57.122	57.175	EPSD	ICGC	45.963	Up-regulation
CMGC_DYRK_DYRK2_DYRK2_ST	Q14194	CRMP1	Q92630	DYRK2	S308	V302M	302	Missense	distal	-6	no	48.268	48.372	EPSD	ICGC;COSMIC	45.963	Up-regulation
CMGC_DYRK_DYRK2_DYRK2_ST	Q14194	CRMP1	Q92630	DYRK2	S308	S308N	308	Missense	central	0	yes	48.268	0.000	EPSD	ICGC;COSMIC	45.963	Loss
CMGC_DYRK_DYRK2_DYRK2_ST	Q14194	CRMP1	Q92630	DYRK2	S308	T312N	312	Missense	distal	4	no	48.268	48.336	EPSD	ICGC	45.963	Up-regulation
CMGC_DYRK_DYRK2_DYRK2_ST	Q14194	CRMP1	Q92630	DYRK2	S308	D315E	315	Missense	distal	7	no	48.268	44.015	EPSD	ICGC	45.963	Loss
CMGC_DYRK_DYRK2_DYRK2_ST	Q14194	CRMP1	Q92630	DYRK2	S522	P528H	528	Missense	distal	6	no	82.280	81.634	PhosphoSitePlus	ICGC	45.963	Down-regulation
Other_BUB_BUB1_ST	Q12834	CDC20	O43683	BUB1	T164	T164P	164	Missense	central	0	yes	0.000	0.000	EPSD	ICGC;COSMIC	0.000	Loss
Other_BUB_BUB1_ST	Q12834	CDC20	O43683	BUB1	T164	T164N	164	Missense	central	0	yes	0.000	0.000	EPSD	ICGC;COSMIC	0.000	Loss
Other_BUB_BUB1_ST	O43683	BUB1	O43683	BUB1	S220	S220F	220	Missense	central	0	yes	0.000	0.000	EPSD	ICGC;COSMIC	0.000	Loss
Other_BUB_BUB1_ST	O43683	BUB1	O43683	BUB1	S524	S524P	524	Missense	central	0	yes	0.000	0.000	EPSD	ICGC	0.000	Loss
Other_BUB_BUB1_ST	O43683	BUB1	O43683	BUB1	T589	T589N	589	Missense	central	0	yes	0.000	0.000	PhosphoSitePlus;EPSD	ICGC	0.000	Loss
Other_BUB_BUB1_ST	O43683	BUB1	O43683	BUB1	S668	S668F	668	Missense	central	0	yes	0.000	0.000	EPSD	ICGC;COSMIC	0.000	Loss
AGC_PKC_PKCh_PRKCE_ST	Q16625	OCLN	Q02156	PRKCE	T403	H397Y	397	Missense	distal	-6	no	15.391	15.505	EPSD;PhosphoSitePlus	ICGC	13.948	Up-regulation
AGC_PKC_PKCh_PRKCE_ST	Q16625	OCLN	Q02156	PRKCE	T403	Y398F	398	Missense	distal	-5	no	15.391	15.376	EPSD;PhosphoSitePlus	ICGC	13.948	Down-regulation
AGC_PKC_PKCh_PRKCE_ST	Q16625	OCLN	Q02156	PRKCE	T404	H397Y	397	Missense	distal	-7	no	13.879	14.252	PhosphoSitePlus;EPSD	ICGC	13.948	Gain
AGC_PKC_PKCh_PRKCE_ST	P11362	FGFR1	Q02156	PRKCE	T403	S410G	410	Missense	distal	7	no	18.942	18.610	EPSD	ICGC;COSMIC	13.948	Down-regulation
AGC_PKC_PKCh_PRKCE_ST	P11362	FGFR1	Q02156	PRKCE	T403	T403N	403	Missense	central	0	yes	18.942	0.000	EPSD	ICGC;COSMIC	13.948	Loss
AGC_PKC_PKCh_PRKCE_ST	P11362	FGFR1	Q02156	PRKCE	T403	K404R	404	Missense	proximal	1	no	18.942	17.952	EPSD	ICGC	13.948	Down-regulation
AGC_PKC_PKCh_PRKCE_ST	P11362	FGFR1	Q02156	PRKCE	T403	M399I	399	Missense	distal	-4	no	18.942	19.067	EPSD	ICGC	13.948	Up-regulation
AGC_PKC_PKCh_PRKCE_ST	Q9HAW7	UGT1A7	Q02156	PRKCE	S432	M438I	438	Missense	distal	6	no	18.682	18.911	PhosphoSitePlus	ICGC;COSMIC	13.948	Up-regulation
AGC_PKC_PKCh_PRKCE_ST	Q9HAW7	UGT1A7	Q02156	PRKCE	S432	R439H	439	Missense	distal	7	no	18.682	17.853	PhosphoSitePlus	ICGC;COSMIC	13.948	Down-regulation
AGC_PKC_PKCh_PRKCE_ST	Q9HAW7	UGT1A7	Q02156	PRKCE	S432	N429S	429	Missense	distal	-3	no	18.682	21.270	PhosphoSitePlus	ICGC;COSMIC	13.948	Up-regulation
AGC_PKC_PKCh_PRKCE_ST	Q9HAW7	UGT1A7	Q02156	PRKCE	S432	I437S	437	Missense	distal	5	no	18.682	18.489	PhosphoSitePlus	ICGC	13.948	Down-regulation
AGC_PKC_PKCh_PRKCE_ST	Q9HAW7	UGT1A7	Q02156	PRKCE	S432	N436K	436	Missense	distal	4	no	18.682	20.224	PhosphoSitePlus	ICGC;COSMIC	13.948	Up-regulation
AGC_PKC_PKCh_PRKCE_ST	P10636	MAPT	Q02156	PRKCE	T167	P160L	160	Missense	distal	-7	no	14.232	14.208	EPSD	ICGC;COSMIC	13.948	Down-regulation
AGC_PKC_PKCh_PRKCE_ST	P10636	MAPT	Q02156	PRKCE	T167	R164T	164	Missense	distal	-3	no	14.232	9.658	EPSD	ICGC;COSMIC	13.948	Loss
AGC_PKC_PKCh_PRKCE_ST	P10636	MAPT	Q02156	PRKCE	T167	A166T	166	Missense	proximal	-1	no	14.232	14.040	EPSD	ICGC	13.948	Down-regulation
AGC_PKC_PKCh_PRKCE_ST	P10636	MAPT	Q02156	PRKCE	S214	G208C	208	Missense	distal	-6	no	15.548	15.539	EPSD	ICGC;COSMIC	13.948	Down-regulation
AGC_PKC_PKCh_PRKCE_ST	P10636	MAPT	Q02156	PRKCE	S214	R211S	211	Missense	distal	-3	no	15.548	10.779	EPSD	ICGC;COSMIC	13.948	Loss
AGC_PKC_PKCh_PRKCE_ST	P10636	MAPT	Q02156	PRKCE	S214	G213E	213	Missense	proximal	-1	no	15.548	15.558	EPSD	ICGC;COSMIC	13.948	Up-regulation
AGC_PKC_PKCh_PRKCE_ST	P10636	MAPT	Q02156	PRKCE	S341	T346I	346	Missense	distal	5	no	20.741	20.617	EPSD	ICGC;COSMIC	13.948	Down-regulation
AGC_PKC_PKCh_PRKCE_ST	P10636	MAPT	Q02156	PRKCE	S341	A337V	337	Missense	distal	-4	no	20.741	20.642	EPSD	ICGC	13.948	Down-regulation
AGC_PKC_PKCh_PRKCE_ST	P10636	MAPT	Q02156	PRKCE	S341	D345E	345	Missense	distal	4	no	20.741	20.096	EPSD	ICGC;COSMIC	13.948	Down-regulation
AGC_PKC_PKCh_PRKCE_ST	P10636	MAPT	Q02156	PRKCE	S355	A349T	349	Missense	distal	-6	no	15.706	15.631	EPSD	ICGC;COSMIC	13.948	Down-regulation
AGC_PKC_PKCh_PRKCE_ST	P10636	MAPT	Q02156	PRKCE	S369	R364W	364	Missense	distal	-5	no	15.708	15.777	EPSD	ICGC;COSMIC	13.948	Up-regulation
AGC_PKC_PKCh_PRKCE_ST	P10636	MAPT	Q02156	PRKCE	S369	P363L	363	Missense	distal	-6	no	15.708	15.689	EPSD	ICGC	13.948	Down-regulation
AGC_PKC_PKCh_PRKCE_ST	P10636	MAPT	Q02156	PRKCE	S438	Y441H	441	Missense	distal	3	no	14.553	13.874	EPSD	ICGC;COSMIC	13.948	Loss
AGC_PKC_PKCh_PRKCE_ST	P10636	MAPT	Q02156	PRKCE	S519	G521R	521	Missense	proximal	2	no	11.031	15.944	EPSD	ICGC;COSMIC	13.948	Gain
AGC_PKC_PKCh_PRKCE_ST	O75689	ADAP1	Q02156	PRKCE	S87	R84Q	84	Missense	distal	-3	no	16.708	11.141	EPSD;PhosphoSitePlus	ICGC;COSMIC	13.948	Loss
AGC_PKC_PKCh_PRKCE_ST	O75689	ADAP1	Q02156	PRKCE	S204	R206H	206	Missense	proximal	2	no	18.789	11.817	EPSD	ICGC;CCLE	13.948	Loss
AGC_PKC_PKCh_PRKCE_ST	Q86XR7	TICAM2	Q02156	PRKCE	S16	H21N	21	Missense	distal	5	no	14.368	14.307	PhosphoSitePlus	ICGC	13.948	Down-regulation
AGC_PKC_PKCh_PRKCE_ST	Q86XR7	TICAM2	Q02156	PRKCE	S16	W17C	17	Missense	proximal	1	no	14.368	14.492	PhosphoSitePlus	ICGC	13.948	Up-regulation
AGC_PKC_PKCh_PRKCE_ST	Q86XR7	TICAM2	Q02156	PRKCE	S16	S10F	10	Missense	distal	-6	no	14.368	14.327	PhosphoSitePlus	ICGC;COSMIC	13.948	Down-regulation
AGC_PKC_PKCh_PRKCE_ST	Q86XR7	TICAM2	Q02156	PRKCE	S34	E31K	31	Missense	distal	-3	no	13.432	20.558	EPSD	ICGC	13.948	Gain
AGC_PKC_PKCh_PRKCE_ST	Q9H9S0	NANOG	Q02156	PRKCE	S71	T70P	70	Missense	proximal	-1	no	16.922	16.880	EPSD	ICGC;COSMIC	13.948	Down-regulation
AGC_PKC_PKCh_PRKCE_ST	Q9H9S0	NANOG	Q02156	PRKCE	S71	P66H	66	Missense	distal	-5	no	16.922	16.941	EPSD	ICGC;COSMIC;CCLE	13.948	Up-regulation
AGC_PKC_PKCh_PRKCE_ST	Q9H9S0	NANOG	Q02156	PRKCE	T78	K82N	82	Missense	distal	4	no	17.942	16.400	PhosphoSitePlus;EPSD	ICGC;COSMIC	13.948	Down-regulation
AGC_PKC_PKCh_PRKCE_ST	Q9H9S0	NANOG	Q02156	PRKCE	T78	A80S	80	Missense	proximal	2	no	17.942	18.673	PhosphoSitePlus;EPSD	ICGC	13.948	Up-regulation
AGC_PKC_PKCh_PRKCE_ST	Q9H9S0	NANOG	Q02156	PRKCE	S79	K82N	82	Missense	distal	3	no	16.737	16.443	EPSD;PhosphoSitePlus	ICGC;COSMIC	13.948	Down-regulation
AGC_PKC_PKCh_PRKCE_ST	Q9H9S0	NANOG	Q02156	PRKCE	S79	A80S	80	Missense	proximal	1	no	16.737	17.436	EPSD;PhosphoSitePlus	ICGC	13.948	Up-regulation
AGC_PKC_PKCh_PRKCE_ST	Q9H9S0	NANOG	Q02156	PRKCE	S135	Q138H	138	Missense	distal	3	no	17.661	16.913	EPSD;PhosphoSitePlus	ICGC;COSMIC	13.948	Down-regulation
AGC_PKC_PKCh_PRKCE_ST	Q9H9S0	NANOG	Q02156	PRKCE	T280	T286I	286	Missense	distal	6	no	21.168	21.180	EPSD;PhosphoSitePlus	ICGC	13.948	Up-regulation
AGC_PKC_PKCh_PRKCE_ST	Q9H9S0	NANOG	Q02156	PRKCE	T280	R282M	282	Missense	proximal	2	no	21.168	7.620	EPSD;PhosphoSitePlus	ICGC;COSMIC	13.948	Loss
AGC_PKC_PKCh_PRKCE_ST	Q9H9S0	NANOG	Q02156	PRKCE	T289	D291N	291	Missense	proximal	2	no	19.380	18.976	EPSD	ICGC	13.948	Down-regulation
AGC_PKC_PKCh_PRKCE_ST	Q9H9S0	NANOG	Q02156	PRKCE	T289	T286I	286	Missense	distal	-3	no	19.380	19.758	EPSD	ICGC	13.948	Up-regulation
AGC_PKC_PKCh_PRKCE_ST	Q9H9S0	NANOG	Q02156	PRKCE	T289	R282M	282	Missense	distal	-7	no	19.380	19.519	EPSD	ICGC;COSMIC	13.948	Up-regulation
AGC_PKC_PKCh_PRKCE_ST	Q14145	KEAP1	Q02156	PRKCE	S599	V604M	604	Missense	distal	5	no	31.933	31.929	EPSD;PhosphoSitePlus	ICGC	13.948	Down-regulation
AGC_PKC_PKCh_PRKCE_ST	Q14145	KEAP1	Q02156	PRKCE	S602	V604M	604	Missense	proximal	2	no	19.003	10.205	PhosphoSitePlus;EPSD	ICGC	13.948	Loss
AGC_PKC_PKCh_PRKCE_ST	Q92934	BAD	Q02156	PRKCE	S75	R72S	72	Missense	distal	-3	no	18.907	14.138	PhosphoSitePlus;EPSD	ICGC	13.948	Down-regulation
AGC_PKC_PKCh_PRKCE_ST	Q92934	BAD	Q02156	PRKCE	S75	T80K	80	Missense	distal	5	no	18.907	18.641	PhosphoSitePlus;EPSD	ICGC	13.948	Down-regulation
AGC_PKC_PKCh_PRKCE_ST	Q92934	BAD	Q02156	PRKCE	S75	S74G	74	Missense	proximal	-1	no	18.907	19.112	PhosphoSitePlus;EPSD	ICGC;COSMIC	13.948	Up-regulation
AGC_PKC_PKCh_PRKCE_ST	Q92934	BAD	Q02156	PRKCE	S97	S99L	99	Missense	proximal	2	no	17.410	16.212	EPSD	ICGC	13.948	Down-regulation
AGC_PKC_PKCh_PRKCE_ST	Q92934	BAD	Q02156	PRKCE	S97	R94W	94	Missense	distal	-3	no	17.410	6.413	EPSD	ICGC	13.948	Loss
AGC_PKC_PKCh_PRKCE_ST	Q92934	BAD	Q02156	PRKCE	S99	S99L	99	Missense	central	0	yes	15.361	0.000	EPSD;PhosphoSitePlus	ICGC	13.948	Loss
AGC_PKC_PKCh_PRKCE_ST	Q92934	BAD	Q02156	PRKCE	S99	R94W	94	Missense	distal	-5	no	15.361	15.430	EPSD;PhosphoSitePlus	ICGC	13.948	Up-regulation
AGC_PKC_PKCh_PRKCE_ST	Q92934	BAD	Q02156	PRKCE	S118	R112S	112	Missense	distal	-6	no	16.614	16.498	EPSD;PhosphoSitePlus	ICGC	13.948	Down-regulation
AGC_PKC_PKCh_PRKCE_ST	Q92934	BAD	Q02156	PRKCE	S163	S167F	167	Missense	distal	4	no	17.205	17.588	EPSD	ICGC	13.948	Up-regulation
AGC_PKC_PKCh_PRKCE_ST	Q92934	BAD	Q02156	PRKCE	S164	S167F	167	Missense	distal	3	no	24.444	24.409	EPSD	ICGC	13.948	Down-regulation
AGC_PKC_PKCh_PRKCE_ST	P78536	ADAM17	Q02156	PRKCE	T87	R89S	89	Missense	proximal	2	no	15.090	8.653	EPSD	ICGC	13.948	Loss
AGC_PKC_PKCh_PRKCE_ST	P78536	ADAM17	Q02156	PRKCE	S360	H361Y	361	Missense	proximal	1	no	16.902	21.053	EPSD	ICGC	13.948	Up-regulation
AGC_PKC_PKCh_PRKCE_ST	P78536	ADAM17	Q02156	PRKCE	S360	P366T	366	Missense	distal	6	no	16.902	16.853	EPSD	ICGC	13.948	Down-regulation
AGC_PKC_PKCh_PRKCE_ST	P78536	ADAM17	Q02156	PRKCE	S360	H361N	361	Missense	proximal	1	no	16.902	17.823	EPSD	ICGC	13.948	Up-regulation
AGC_PKC_PKCh_PRKCE_ST	P78536	ADAM17	Q02156	PRKCE	S608	P613T	613	Missense	distal	5	no	20.655	20.865	EPSD	ICGC	13.948	Up-regulation
AGC_PKC_PKCh_PRKCE_ST	P78536	ADAM17	Q02156	PRKCE	T761	L754M	754	Missense	distal	-7	no	14.126	14.587	EPSD	ICGC;COSMIC	13.948	Up-regulation
AGC_PKC_PKCh_PRKCE_ST	P16220	CREB1	Q02156	PRKCE	S133	D140A	140	Missense	distal	7	no	22.554	22.756	PhosphoSitePlus	ICGC;COSMIC	13.948	Up-regulation
AGC_PKC_PKCh_PRKCE_ST	P43629	KIR3DL1	Q02156	PRKCE	T118	N120K	120	Missense	proximal	2	no	15.832	22.288	EPSD	ICGC;COSMIC	13.948	Up-regulation
AGC_PKC_PKCh_PRKCE_ST	P43629	KIR3DL1	Q02156	PRKCE	S415	T412M	412	Missense	distal	-3	no	17.613	11.967	PhosphoSitePlus	ICGC;COSMIC	13.948	Loss
AGC_PKC_PKCh_PRKCE_ST	P43629	KIR3DL1	Q02156	PRKCE	S415	P418T	418	Missense	distal	3	no	17.613	17.090	PhosphoSitePlus	ICGC	13.948	Down-regulation
AGC_PKC_PKCh_PRKCE_ST	P43629	KIR3DL1	Q02156	PRKCE	S415	P414T	414	Missense	proximal	-1	no	17.613	17.655	PhosphoSitePlus	ICGC	13.948	Up-regulation
AGC_PKC_PKCh_PRKCE_ST	P43629	KIR3DL1	Q02156	PRKCE	S415	Q416L	416	Missense	proximal	1	no	17.613	18.663	PhosphoSitePlus	ICGC	13.948	Up-regulation
AGC_PKC_PKCh_PRKCE_ST	P43629	KIR3DL1	Q02156	PRKCE	S415	R413L	413	Missense	proximal	-2	no	17.613	14.509	PhosphoSitePlus	ICGC;COSMIC	13.948	Down-regulation
AGC_PKC_PKCh_PRKCE_ST	P43629	KIR3DL1	Q02156	PRKCE	S415	P418L	418	Missense	distal	3	no	17.613	17.415	PhosphoSitePlus	ICGC	13.948	Down-regulation
AGC_PKC_PKCh_PRKCE_ST	P43629	KIR3DL1	Q02156	PRKCE	T420	P418T	418	Missense	proximal	-2	no	14.228	12.579	EPSD	ICGC	13.948	Loss
AGC_PKC_PKCh_PRKCE_ST	P43629	KIR3DL1	Q02156	PRKCE	T420	P414T	414	Missense	distal	-6	no	14.228	14.141	EPSD	ICGC	13.948	Down-regulation
AGC_PKC_PKCh_PRKCE_ST	P43629	KIR3DL1	Q02156	PRKCE	T420	Q416L	416	Missense	distal	-4	no	14.228	14.315	EPSD	ICGC	13.948	Up-regulation
AGC_PKC_PKCh_PRKCE_ST	P43629	KIR3DL1	Q02156	PRKCE	T420	R413L	413	Missense	distal	-7	no	14.228	13.906	EPSD	ICGC;COSMIC	13.948	Loss
AGC_PKC_PKCh_PRKCE_ST	P43629	KIR3DL1	Q02156	PRKCE	T420	P418L	418	Missense	proximal	-2	no	14.228	11.795	EPSD	ICGC	13.948	Loss
AGC_PKC_PKCh_PRKCE_ST	P43629	KIR3DL1	Q02156	PRKCE	T420	T425I	425	Missense	distal	5	no	14.228	14.103	EPSD	ICGC	13.948	Down-regulation
AGC_PKC_PKCh_PRKCE_ST	P43629	KIR3DL1	Q02156	PRKCE	S442	R437I	437	Missense	distal	-5	no	15.499	15.536	EPSD	ICGC	13.948	Up-regulation
AGC_PKC_PKCh_PRKCE_ST	P43629	KIR3DL1	Q02156	PRKCE	S442	S438F	438	Missense	distal	-4	no	15.499	15.351	EPSD	ICGC	13.948	Down-regulation
AGC_PKC_PKCh_PRKCE_ST	P43629	KIR3DL1	Q02156	PRKCE	S442	R437K	437	Missense	distal	-5	no	15.499	15.519	EPSD	ICGC	13.948	Up-regulation
AGC_PKC_PKCh_PRKCE_ST	Q9UBS0	RPS6KB2	Q02156	PRKCE	S410	F404L	404	Missense	distal	-6	no	17.760	17.769	EPSD	ICGC	13.948	Up-regulation
AGC_PKC_PKCh_PRKCE_ST	Q9UBS0	RPS6KB2	Q02156	PRKCE	S416	V422I	422	Missense	distal	6	no	15.168	15.114	EPSD	ICGC;COSMIC;CCLE	13.948	Down-regulation
AGC_PKC_PKCh_PRKCE_ST	Q9UBS0	RPS6KB2	Q02156	PRKCE	S416	A420V	420	Missense	distal	4	no	15.168	16.842	EPSD	ICGC;COSMIC	13.948	Up-regulation
AGC_PKC_PKCh_PRKCE_ST	P05783	KRT18	Q02156	PRKCE	S53	V48M	48	Missense	distal	-5	no	23.709	23.738	PhosphoSitePlus	ICGC;COSMIC	13.948	Up-regulation
AGC_PKC_PKCh_PRKCE_ST	P05783	KRT18	Q02156	PRKCE	S53	R50C	50	Missense	distal	-3	no	23.709	15.619	PhosphoSitePlus	ICGC;COSMIC	13.948	Down-regulation
AGC_PKC_PKCh_PRKCE_ST	P05783	KRT18	Q02156	PRKCE	S53	G56D	56	Missense	distal	3	no	23.709	23.678	PhosphoSitePlus	ICGC;COSMIC	13.948	Down-regulation
AGC_PKC_PKCh_PRKCE_ST	P05783	KRT18	Q02156	PRKCE	S53	G59W	59	Missense	distal	6	no	23.709	24.401	PhosphoSitePlus	ICGC;COSMIC	13.948	Up-regulation
AGC_PKC_PKCh_PRKCE_ST	P05783	KRT18	Q02156	PRKCE	S53	I46T	46	Missense	distal	-7	no	23.709	23.651	PhosphoSitePlus	ICGC;COSMIC	13.948	Down-regulation
AGC_PKC_PKCh_PRKCE_ST	P05783	KRT18	Q02156	PRKCE	S100	R106L	106	Missense	distal	6	no	16.090	16.528	EPSD	ICGC;COSMIC	13.948	Up-regulation
AGC_PKC_PKCh_PRKCE_ST	P05783	KRT18	Q02156	PRKCE	S100	R107K	107	Missense	distal	7	no	16.090	16.682	EPSD	ICGC;COSMIC	13.948	Up-regulation
AGC_PKC_PKCh_PRKCE_ST	P05783	KRT18	Q02156	PRKCE	S100	R106W	106	Missense	distal	6	no	16.090	17.126	EPSD	ICGC;COSMIC	13.948	Up-regulation
AGC_PKC_PKCh_PRKCE_ST	P05783	KRT18	Q02156	PRKCE	S100	T103N	103	Missense	distal	3	no	16.090	16.716	EPSD	ICGC;COSMIC	13.948	Up-regulation
AGC_PKC_PKCh_PRKCE_ST	P05783	KRT18	Q02156	PRKCE	S100	E102D	102	Missense	proximal	2	no	16.090	16.705	EPSD	ICGC;COSMIC	13.948	Up-regulation
AGC_PKC_PKCh_PRKCE_ST	P05783	KRT18	Q02156	PRKCE	S110	R106L	106	Missense	distal	-4	no	13.755	13.986	EPSD	ICGC;COSMIC	13.948	Gain
AGC_PKC_PKCh_PRKCE_ST	P05783	KRT18	Q02156	PRKCE	S110	R106W	106	Missense	distal	-4	no	13.755	14.308	EPSD	ICGC;COSMIC	13.948	Gain
AGC_PKC_PKCh_PRKCE_ST	P05783	KRT18	Q02156	PRKCE	S420	K417Q	417	Missense	distal	-3	no	16.023	10.439	EPSD	ICGC;COSMIC	13.948	Loss
AGC_PKC_PKCh_PRKCE_ST	P05783	KRT18	Q02156	PRKCE	T422	K417Q	417	Missense	distal	-5	no	15.978	15.969	EPSD	ICGC;COSMIC	13.948	Down-regulation
AGC_PKC_PKCh_PRKCE_ST	Q02156	PRKCE	Q02156	PRKCE	T228	P229L	229	Missense	proximal	1	no	13.654	15.017	EPSD	ICGC;COSMIC	13.948	Gain
AGC_PKC_PKCh_PRKCE_ST	Q02156	PRKCE	Q02156	PRKCE	S234	P229L	229	Missense	distal	-5	no	18.167	18.162	EPSD;PhosphoSitePlus	ICGC;COSMIC	13.948	Down-regulation
AGC_PKC_PKCh_PRKCE_ST	Q02156	PRKCE	Q02156	PRKCE	S316	N315S	315	Missense	proximal	-1	no	14.918	15.042	PhosphoSitePlus;EPSD	ICGC;COSMIC	13.948	Up-regulation
AGC_PKC_PKCh_PRKCE_ST	Q02156	PRKCE	Q02156	PRKCE	S316	G317S	317	Missense	proximal	1	no	14.918	14.300	PhosphoSitePlus;EPSD	ICGC	13.948	Down-regulation
AGC_PKC_PKCh_PRKCE_ST	Q02156	PRKCE	Q02156	PRKCE	S380	Q385H	385	Missense	distal	5	no	14.241	14.356	EPSD	ICGC;COSMIC	13.948	Up-regulation
AGC_PKC_PKCh_PRKCE_ST	Q02156	PRKCE	Q02156	PRKCE	T566	V562A	562	Missense	distal	-4	no	14.837	14.936	EPSD	ICGC;COSMIC	13.948	Up-regulation
AGC_PKC_PKCh_PRKCE_ST	Q02156	PRKCE	Q02156	PRKCE	T566	F567L	567	Missense	proximal	1	no	14.837	13.735	EPSD	ICGC	13.948	Loss
AGC_PKC_PKCh_PRKCE_ST	Q02156	PRKCE	Q02156	PRKCE	T566	G569E	569	Missense	distal	3	no	14.837	14.384	EPSD	ICGC;COSMIC	13.948	Down-regulation
AGC_PKC_PKCh_PRKCE_ST	Q02156	PRKCE	Q02156	PRKCE	S729	F725C	725	Missense	distal	-4	no	18.653	18.800	EPSD;PhosphoSitePlus	ICGC	13.948	Up-regulation
AGC_PKC_PKCh_PRKCE_ST	Q96A00	PPP1R14A	Q02156	PRKCE	S12	R9C	9	Missense	distal	-3	no	15.055	6.965	EPSD	ICGC	13.948	Loss
AGC_PKC_PKCh_PRKCE_ST	Q96A00	PPP1R14A	Q02156	PRKCE	T38	Q31K	31	Missense	distal	-7	no	20.543	20.504	PhosphoSitePlus	ICGC	13.948	Down-regulation
AGC_PKC_PKCh_PRKCE_ST	Q96A00	PPP1R14A	Q02156	PRKCE	T38	H34Y	34	Missense	distal	-4	no	20.543	20.216	PhosphoSitePlus	ICGC;COSMIC	13.948	Down-regulation
AGC_PKC_PKCh_PRKCE_ST	Q96A00	PPP1R14A	Q02156	PRKCE	T38	H34Q	34	Missense	distal	-4	no	20.543	20.222	PhosphoSitePlus	ICGC	13.948	Down-regulation
AGC_PKC_PKCh_PRKCE_ST	Q96A00	PPP1R14A	Q02156	PRKCE	T38	A35T	35	Missense	distal	-3	no	20.543	20.132	PhosphoSitePlus	ICGC;COSMIC	13.948	Down-regulation
AGC_PKC_PKCh_PRKCE_ST	P46940	IQGAP1	Q02156	PRKCE	S91	V89L	89	Missense	proximal	-2	no	18.534	16.993	EPSD	ICGC	13.948	Down-regulation
AGC_PKC_PKCh_PRKCE_ST	P46940	IQGAP1	Q02156	PRKCE	S91	R98L	98	Missense	distal	7	no	18.534	17.725	EPSD	ICGC;COSMIC	13.948	Down-regulation
AGC_PKC_PKCh_PRKCE_ST	P46940	IQGAP1	Q02156	PRKCE	S91	L92Q	92	Missense	proximal	1	no	18.534	17.483	EPSD	ICGC;COSMIC	13.948	Down-regulation
AGC_PKC_PKCh_PRKCE_ST	P46940	IQGAP1	Q02156	PRKCE	S280	E283Q	283	Missense	distal	3	no	17.797	18.050	EPSD	ICGC;COSMIC	13.948	Up-regulation
AGC_PKC_PKCh_PRKCE_ST	P46940	IQGAP1	Q02156	PRKCE	S360	S360F	360	Missense	central	0	yes	17.160	0.000	EPSD	ICGC;COSMIC	13.948	Loss
AGC_PKC_PKCh_PRKCE_ST	P46940	IQGAP1	Q02156	PRKCE	S480	S480N	480	Missense	central	0	yes	15.354	0.000	EPSD	ICGC	13.948	Loss
AGC_PKC_PKCh_PRKCE_ST	P46940	IQGAP1	Q02156	PRKCE	T557	Q555K	555	Missense	proximal	-2	no	13.102	14.507	EPSD	ICGC;COSMIC	13.948	Gain
AGC_PKC_PKCh_PRKCE_ST	P46940	IQGAP1	Q02156	PRKCE	S934	L937R	937	Missense	distal	3	no	15.531	15.917	EPSD	ICGC;COSMIC	13.948	Up-regulation
AGC_PKC_PKCh_PRKCE_ST	P46940	IQGAP1	Q02156	PRKCE	S962	S962I	962	Missense	central	0	yes	14.637	0.000	EPSD	ICGC;COSMIC	13.948	Loss
AGC_PKC_PKCh_PRKCE_ST	P46940	IQGAP1	Q02156	PRKCE	S1237	H1234R	1234	Missense	distal	-3	no	14.075	19.295	EPSD	ICGC;COSMIC	13.948	Up-regulation
AGC_PKC_PKCh_PRKCE_ST	P05091	ALDH2	Q02156	PRKCE	T202	A201S	201	Missense	proximal	-1	no	14.339	14.543	PhosphoSitePlus;EPSD	ICGC	13.948	Up-regulation
AGC_PKC_PKCh_PRKCE_ST	P05091	ALDH2	Q02156	PRKCE	S276	G275V	275	Missense	proximal	-1	no	15.744	15.139	EPSD	ICGC;COSMIC	13.948	Down-regulation
AGC_PKC_PKCh_PRKCE_ST	P05091	ALDH2	Q02156	PRKCE	S276	A274V	274	Missense	proximal	-2	no	15.744	15.908	EPSD	ICGC	13.948	Up-regulation
AGC_PKC_PKCh_PRKCE_ST	Q15139	PRKD1	Q02156	PRKCE	T214	V207F	207	Missense	distal	-7	no	15.116	15.050	EPSD	ICGC;COSMIC	13.948	Down-regulation
AGC_PKC_PKCh_PRKCE_ST	Q15139	PRKD1	Q02156	PRKCE	T214	R216H	216	Missense	proximal	2	no	15.116	8.145	EPSD	ICGC	13.948	Loss
AGC_PKC_PKCh_PRKCE_ST	Q15139	PRKD1	Q02156	PRKCE	S237	E244V	244	Missense	distal	7	no	16.139	15.409	EPSD	ICGC;COSMIC	13.948	Down-regulation
AGC_PKC_PKCh_PRKCE_ST	Q15139	PRKD1	Q02156	PRKCE	S412	R418K	418	Missense	distal	6	no	14.595	15.018	EPSD	ICGC;COSMIC	13.948	Up-regulation
AGC_PKC_PKCh_PRKCE_ST	Q15139	PRKD1	Q02156	PRKCE	S738	R740W	740	Missense	proximal	2	no	20.516	7.843	PhosphoSitePlus;EPSD	ICGC;COSMIC;GDSC;CCLE	13.948	Loss
AGC_PKC_PKCh_PRKCE_ST	Q15139	PRKD1	Q02156	PRKCE	S738	R740L	740	Missense	proximal	2	no	20.516	12.881	PhosphoSitePlus;EPSD	ICGC;COSMIC	13.948	Loss
AGC_PKC_PKCh_PRKCE_ST	Q15139	PRKD1	Q02156	PRKCE	S742	R740W	740	Missense	proximal	-2	no	17.260	14.042	EPSD;PhosphoSitePlus	ICGC;COSMIC;GDSC;CCLE	13.948	Down-regulation
AGC_PKC_PKCh_PRKCE_ST	Q15139	PRKD1	Q02156	PRKCE	S742	R740L	740	Missense	proximal	-2	no	17.260	14.156	EPSD;PhosphoSitePlus	ICGC;COSMIC	13.948	Down-regulation
AGC_PKC_PKCh_PRKCE_ST	Q15139	PRKD1	Q02156	PRKCE	S829	V830L	830	Missense	proximal	1	no	18.738	19.251	EPSD	ICGC;COSMIC	13.948	Up-regulation
AGC_PKC_PKCh_PRKCE_ST	P00533	EGFR	Q02156	PRKCE	S1190	Y1197C	1197	Missense	distal	7	no	15.423	14.643	EPSD	ICGC;COSMIC	13.948	Down-regulation
AGC_PKC_PKCh_PRKCE_ST	P00533	EGFR	Q02156	PRKCE	T1191	Y1197C	1197	Missense	distal	6	no	16.207	16.417	EPSD	ICGC;COSMIC	13.948	Up-regulation
AGC_PKC_PKCh_PRKCE_ST	P00533	EGFR	Q02156	PRKCE	T1191	L1198I	1198	Missense	distal	7	no	16.207	16.555	EPSD	ICGC;COSMIC	13.948	Up-regulation
AGC_PKC_PKCh_PRKCE_ST	P00533	EGFR	Q02156	PRKCE	S1204	Y1197C	1197	Missense	distal	-7	no	19.460	19.446	EPSD	ICGC;COSMIC	13.948	Down-regulation
AGC_PKC_PKCh_PRKCE_ST	P00533	EGFR	Q02156	PRKCE	S1204	L1198I	1198	Missense	distal	-6	no	19.460	19.491	EPSD	ICGC;COSMIC	13.948	Up-regulation
AGC_PKC_PKCh_PRKCE_ST	Q9BR76	CORO1B	Q02156	PRKCE	S199	R206H	206	Missense	distal	7	no	15.204	14.374	EPSD	ICGC;COSMIC	13.948	Down-regulation
AGC_PKC_PKCh_PRKCE_ST	Q9BR76	CORO1B	Q02156	PRKCE	S199	S199R	199	Missense	central	0	yes	15.204	0.000	EPSD	ICGC	13.948	Loss
AGC_PKC_PKCh_PRKCE_ST	Q9BR76	CORO1B	Q02156	PRKCE	S199	D204N	204	Missense	distal	5	no	15.204	15.145	EPSD	ICGC	13.948	Down-regulation
AGC_PKC_PKCh_PRKCE_ST	Q9BR76	CORO1B	Q02156	PRKCE	T209	R214W	214	Missense	distal	5	no	15.144	15.913	EPSD	ICGC;COSMIC	13.948	Up-regulation
AGC_PKC_PKCh_PRKCE_ST	Q9BR76	CORO1B	Q02156	PRKCE	T209	R206H	206	Missense	distal	-3	no	15.144	9.924	EPSD	ICGC;COSMIC	13.948	Loss
AGC_PKC_PKCh_PRKCE_ST	Q9BR76	CORO1B	Q02156	PRKCE	T209	D204N	204	Missense	distal	-5	no	15.144	15.135	EPSD	ICGC	13.948	Down-regulation
AGC_PKC_PKCh_PRKCE_ST	Q9BR76	CORO1B	Q02156	PRKCE	S407	R402L	402	Missense	distal	-5	no	15.496	15.509	EPSD	ICGC;COSMIC	13.948	Up-regulation
AGC_PKC_PKCh_PRKCE_ST	Q9BR76	CORO1B	Q02156	PRKCE	S423	P421L	421	Missense	proximal	-2	no	14.321	11.888	EPSD	ICGC;COSMIC	13.948	Loss
AGC_PKC_PKCh_PRKCE_ST	Q9BR76	CORO1B	Q02156	PRKCE	T439	D437G	437	Missense	proximal	-2	no	13.222	14.622	EPSD	ICGC;COSMIC	13.948	Gain
AGC_PKC_PKCh_PRKCE_ST	P23975	SLC6A2	Q02156	PRKCE	S259	S259P	259	Missense	central	0	yes	17.719	0.000	PhosphoSitePlus	ICGC;COSMIC	13.948	Loss
AGC_PKC_PKCh_PRKCE_ST	P23975	SLC6A2	Q02156	PRKCE	S259	G255V	255	Missense	distal	-4	no	17.719	17.600	PhosphoSitePlus	ICGC	13.948	Down-regulation
AGC_PKC_PKCh_PRKCE_ST	P23975	SLC6A2	Q02156	PRKCE	S259	W264C	264	Missense	distal	5	no	17.719	17.239	PhosphoSitePlus	ICGC	13.948	Down-regulation
AGC_PKC_PKCh_PRKCE_ST	Q5JXC2	MIIP	Q02156	PRKCE	S113	S116L	116	Missense	distal	3	no	16.008	15.871	EPSD	ICGC;COSMIC	13.948	Down-regulation
AGC_PKC_PKCh_PRKCE_ST	Q5JXC2	MIIP	Q02156	PRKCE	S113	G107C	107	Missense	distal	-6	no	16.008	15.999	EPSD	ICGC	13.948	Down-regulation
AGC_PKC_PKCh_PRKCE_ST	Q5JXC2	MIIP	Q02156	PRKCE	S303	D308N	308	Missense	distal	5	no	18.987	18.928	PhosphoSitePlus	ICGC	13.948	Down-regulation
AGC_PKC_PKCh_PRKCE_ST	P20339	RAB5A	Q02156	PRKCE	T7	G11R	11	Missense	distal	4	no	17.367	16.636	PhosphoSitePlus	ICGC;COSMIC	13.948	Down-regulation
AGC_PKC_PKCh_PRKCE_ST	P20339	RAB5A	Q02156	PRKCE	T7	T14M	14	Missense	distal	7	no	17.367	17.690	PhosphoSitePlus	ICGC	13.948	Up-regulation
AGC_PKC_PKCh_PRKCE_ST	P20339	RAB5A	Q02156	PRKCE	T7	P12L	12	Missense	distal	5	no	17.367	17.245	PhosphoSitePlus	ICGC	13.948	Down-regulation
AGC_PKC_PKCh_PRKCE_ST	P20339	RAB5A	Q02156	PRKCE	T7	P9H	9	Missense	proximal	2	no	17.367	16.180	PhosphoSitePlus	ICGC;COSMIC	13.948	Down-regulation
AGC_PKC_PKCh_PRKCE_ST	P20339	RAB5A	Q02156	PRKCE	T7	T7K	7	Missense	central	0	yes	17.367	0.000	PhosphoSitePlus	ICGC;COSMIC	13.948	Loss
AGC_PKC_PKCh_PRKCE_ST	P20339	RAB5A	Q02156	PRKCE	T14	G11R	11	Missense	distal	-3	no	10.672	17.930	EPSD	ICGC;COSMIC	13.948	Gain
AGC_PKC_PKCh_PRKCE_ST	P20339	RAB5A	Q02156	PRKCE	S123	I128L	128	Missense	distal	5	no	16.300	16.092	EPSD	ICGC	13.948	Down-regulation
AGC_PKC_PKCh_PRKCE_ST	P20339	RAB5A	Q02156	PRKCE	S123	K116N	116	Missense	distal	-7	no	16.300	16.274	EPSD	ICGC;COSMIC	13.948	Down-regulation
AGC_PKC_PKCh_PRKCE_ST	P05556	ITGB1	Q02156	PRKCE	S61	A62E	62	Missense	proximal	1	no	16.146	15.568	EPSD	ICGC	13.948	Down-regulation
AGC_PKC_PKCh_PRKCE_ST	P05556	ITGB1	Q02156	PRKCE	S61	Q55K	55	Missense	distal	-6	no	16.146	16.211	EPSD	ICGC	13.948	Up-regulation
AGC_PKC_PKCh_PRKCE_ST	P05556	ITGB1	Q02156	PRKCE	S61	Q55H	55	Missense	distal	-6	no	16.146	16.073	EPSD	ICGC;COSMIC	13.948	Down-regulation
AGC_PKC_PKCh_PRKCE_ST	P05556	ITGB1	Q02156	PRKCE	S327	H321N	321	Missense	distal	-6	no	14.061	14.075	EPSD	ICGC;GDSC	13.948	Up-regulation
AGC_PKC_PKCh_PRKCE_ST	P05556	ITGB1	Q02156	PRKCE	S549	I547M	547	Missense	proximal	-2	no	12.389	14.603	EPSD	ICGC;COSMIC	13.948	Gain
AGC_PKC_PKCh_PRKCE_ST	P05556	ITGB1	Q02156	PRKCE	S785	P781A	781	Missense	distal	-4	no	16.060	16.127	EPSD	ICGC;COSMIC	13.948	Up-regulation
AGC_PKC_PKCh_PRKCE_ST	P05556	ITGB1	Q02156	PRKCE	S785	V787I	787	Missense	proximal	2	no	16.060	14.003	EPSD	ICGC;COSMIC;GDSC;CCLE	13.948	Down-regulation
AGC_PKC_PKCh_PRKCE_ST	P05556	ITGB1	Q02156	PRKCE	S785	P781L	781	Missense	distal	-4	no	16.060	16.064	EPSD	ICGC;COSMIC	13.948	Up-regulation
AGC_PKC_PKCh_PRKCE_ST	P05556	ITGB1	Q02156	PRKCE	T788	P781A	781	Missense	distal	-7	no	15.986	16.050	PhosphoSitePlus;EPSD	ICGC;COSMIC	13.948	Up-regulation
AGC_PKC_PKCh_PRKCE_ST	P05556	ITGB1	Q02156	PRKCE	T788	Y795C	795	Missense	distal	7	no	15.986	15.207	PhosphoSitePlus;EPSD	ICGC	13.948	Down-regulation
AGC_PKC_PKCh_PRKCE_ST	P05556	ITGB1	Q02156	PRKCE	T788	P793S	793	Missense	distal	5	no	15.986	15.879	PhosphoSitePlus;EPSD	ICGC;COSMIC	13.948	Down-regulation
AGC_PKC_PKCh_PRKCE_ST	P05556	ITGB1	Q02156	PRKCE	T788	V787I	787	Missense	proximal	-1	no	15.986	15.742	PhosphoSitePlus;EPSD	ICGC;COSMIC;GDSC;CCLE	13.948	Down-regulation
AGC_PKC_PKCh_PRKCE_ST	P05556	ITGB1	Q02156	PRKCE	T788	P781L	781	Missense	distal	-7	no	15.986	15.962	PhosphoSitePlus;EPSD	ICGC;COSMIC	13.948	Down-regulation
AGC_PKC_PKCh_PRKCE_ST	P05556	ITGB1	Q02156	PRKCE	T789	Y795C	795	Missense	distal	6	no	14.997	15.207	EPSD;PhosphoSitePlus	ICGC	13.948	Up-regulation
AGC_PKC_PKCh_PRKCE_ST	P05556	ITGB1	Q02156	PRKCE	T789	P793S	793	Missense	distal	4	no	14.997	15.123	EPSD;PhosphoSitePlus	ICGC;COSMIC	13.948	Up-regulation
AGC_PKC_PKCh_PRKCE_ST	P05556	ITGB1	Q02156	PRKCE	T789	V787I	787	Missense	proximal	-2	no	14.997	14.108	EPSD;PhosphoSitePlus	ICGC;COSMIC;GDSC;CCLE	13.948	Down-regulation
AGC_PKC_PKCh_PRKCE_ST	Q96GD4	AURKB	Q02156	PRKCE	S7	Y8C	8	Missense	proximal	1	no	18.330	15.145	EPSD	ICGC	13.948	Down-regulation
AGC_PKC_PKCh_PRKCE_ST	Q96GD4	AURKB	Q02156	PRKCE	S7	P9H	9	Missense	proximal	2	no	18.330	17.143	EPSD	ICGC;COSMIC	13.948	Down-regulation
AGC_PKC_PKCh_PRKCE_ST	Q96GD4	AURKB	Q02156	PRKCE	S7	A2S	2	Missense	distal	-5	no	18.330	18.336	EPSD	ICGC;COSMIC	13.948	Up-regulation
AGC_PKC_PKCh_PRKCE_ST	P28329	CHAT	Q02156	PRKCE	S594	L597F	597	Missense	distal	3	no	16.427	16.530	EPSD	ICGC;COSMIC	13.948	Up-regulation
AGC_PKC_PKCh_PRKCE_ST	P28329	CHAT	Q02156	PRKCE	S594	A590T	590	Missense	distal	-4	no	16.427	16.328	EPSD	ICGC;COSMIC	13.948	Down-regulation
AGC_PKC_PKCh_PRKCE_ST	P17302	GJA1	Q02156	PRKCE	S244	D245V	245	Missense	proximal	1	no	15.603	15.217	EPSD	ICGC	13.948	Down-regulation
AGC_PKC_PKCh_PRKCE_ST	P17302	GJA1	Q02156	PRKCE	S244	A249V	249	Missense	distal	5	no	15.603	15.380	EPSD	ICGC;COSMIC;GDSC;CCLE	13.948	Down-regulation
AGC_PKC_PKCh_PRKCE_ST	P17302	GJA1	Q02156	PRKCE	S244	V240G	240	Missense	distal	-4	no	15.603	15.722	EPSD	ICGC;COSMIC	13.948	Up-regulation
AGC_PKC_PKCh_PRKCE_ST	P17302	GJA1	Q02156	PRKCE	S244	R239L	239	Missense	distal	-5	no	15.603	15.616	EPSD	ICGC;COSMIC	13.948	Up-regulation
AGC_PKC_PKCh_PRKCE_ST	P17302	GJA1	Q02156	PRKCE	S244	V240L	240	Missense	distal	-4	no	15.603	15.639	EPSD	ICGC;COSMIC	13.948	Up-regulation
AGC_PKC_PKCh_PRKCE_ST	P17302	GJA1	Q02156	PRKCE	S244	G242R	242	Missense	proximal	-2	no	15.603	16.193	EPSD	ICGC;COSMIC;GDSC	13.948	Up-regulation
AGC_PKC_PKCh_PRKCE_ST	P17302	GJA1	Q02156	PRKCE	S296	K303N	303	Missense	distal	7	no	17.123	16.275	EPSD	ICGC	13.948	Down-regulation
AGC_PKC_PKCh_PRKCE_ST	P17302	GJA1	Q02156	PRKCE	S296	D292N	292	Missense	distal	-4	no	17.123	17.295	EPSD	ICGC	13.948	Up-regulation
AGC_PKC_PKCh_PRKCE_ST	P17302	GJA1	Q02156	PRKCE	S296	R293I	293	Missense	distal	-3	no	17.123	12.926	EPSD	ICGC	13.948	Loss
AGC_PKC_PKCh_PRKCE_ST	P17302	GJA1	Q02156	PRKCE	S296	T290N	290	Missense	distal	-6	no	17.123	17.174	EPSD	ICGC	13.948	Up-regulation
AGC_PKC_PKCh_PRKCE_ST	P17302	GJA1	Q02156	PRKCE	S296	T290I	290	Missense	distal	-6	no	17.123	17.220	EPSD	ICGC;COSMIC	13.948	Up-regulation
AGC_PKC_PKCh_PRKCE_ST	P17302	GJA1	Q02156	PRKCE	S296	V289L	289	Missense	distal	-7	no	17.123	17.184	EPSD	ICGC;COSMIC	13.948	Up-regulation
AGC_PKC_PKCh_PRKCE_ST	P17302	GJA1	Q02156	PRKCE	S364	R362Q	362	Missense	proximal	-2	no	23.628	22.657	EPSD	ICGC;COSMIC;GDSC	13.948	Down-regulation
AGC_PKC_PKCh_PRKCE_ST	P17302	GJA1	Q02156	PRKCE	S364	D360E	360	Missense	distal	-4	no	23.628	23.606	EPSD	ICGC;COSMIC	13.948	Down-regulation
AGC_PKC_PKCh_PRKCE_ST	P17302	GJA1	Q02156	PRKCE	S364	R370H	370	Missense	distal	6	no	23.628	24.315	EPSD	ICGC;GDSC;CCLE	13.948	Up-regulation
AGC_PKC_PKCh_PRKCE_ST	P17302	GJA1	Q02156	PRKCE	S365	R362Q	362	Missense	distal	-3	no	18.789	13.222	EPSD	ICGC;COSMIC;GDSC	13.948	Loss
AGC_PKC_PKCh_PRKCE_ST	P17302	GJA1	Q02156	PRKCE	S365	D360E	360	Missense	distal	-5	no	18.789	18.766	EPSD	ICGC;COSMIC	13.948	Down-regulation
AGC_PKC_PKCh_PRKCE_ST	P17302	GJA1	Q02156	PRKCE	S365	R370H	370	Missense	distal	5	no	18.789	19.153	EPSD	ICGC;GDSC;CCLE	13.948	Up-regulation
AGC_PKC_PKCh_PRKCE_ST	P17302	GJA1	Q02156	PRKCE	S368	R362Q	362	Missense	distal	-6	no	25.616	25.512	PhosphoSitePlus	ICGC;COSMIC;GDSC	13.948	Down-regulation
AGC_PKC_PKCh_PRKCE_ST	P17302	GJA1	Q02156	PRKCE	S368	R370H	370	Missense	proximal	2	no	25.616	18.645	PhosphoSitePlus	ICGC;GDSC;CCLE	13.948	Down-regulation
AGC_PKC_PKCh_PRKCE_ST	P17302	GJA1	Q02156	PRKCE	S369	R362Q	362	Missense	distal	-7	no	20.672	20.491	EPSD	ICGC;COSMIC;GDSC	13.948	Down-regulation
AGC_PKC_PKCh_PRKCE_ST	P17302	GJA1	Q02156	PRKCE	S369	R370H	370	Missense	proximal	1	no	20.672	18.120	EPSD	ICGC;GDSC;CCLE	13.948	Down-regulation
AGC_PKC_PKCh_PRKCE_ST	P17302	GJA1	Q02156	PRKCE	S372	D378N	378	Missense	distal	6	no	28.412	28.701	EPSD	ICGC	13.948	Up-regulation
AGC_PKC_PKCh_PRKCE_ST	P17302	GJA1	Q02156	PRKCE	S372	R370H	370	Missense	proximal	-2	no	28.412	25.862	EPSD	ICGC;GDSC;CCLE	13.948	Down-regulation
AGC_PKC_PKCh_PRKCE_ST	P17302	GJA1	Q02156	PRKCE	S373	D378N	378	Missense	distal	5	no	21.819	21.759	EPSD	ICGC	13.948	Down-regulation
AGC_PKC_PKCh_PRKCE_ST	P17302	GJA1	Q02156	PRKCE	S373	R370H	370	Missense	distal	-3	no	21.819	16.599	EPSD	ICGC;GDSC;CCLE	13.948	Down-regulation
AGC_PKC_PKCh_PRKCE_ST	Q9BZL6	PRKD2	Q02156	PRKCE	S529	A528E	528	Missense	proximal	-1	no	14.764	15.181	EPSD	ICGC	13.948	Up-regulation
AGC_PKC_PKCh_PRKCE_ST	P40763	STAT3	Q02156	PRKCE	S25	M28V	28	Missense	distal	3	no	14.117	14.316	EPSD	ICGC;COSMIC	13.948	Up-regulation
AGC_PKC_PKCh_PRKCE_ST	P40763	STAT3	Q02156	PRKCE	S25	R31W	31	Missense	distal	6	no	14.117	15.152	EPSD	ICGC;COSMIC	13.948	Up-regulation
AGC_PKC_PKCh_PRKCE_ST	P40763	STAT3	Q02156	PRKCE	S25	Y22H	22	Missense	distal	-3	no	14.117	14.714	EPSD	ICGC;COSMIC	13.948	Up-regulation
AGC_PKC_PKCh_PRKCE_ST	P40763	STAT3	Q02156	PRKCE	T412	E415V	415	Missense	distal	3	no	16.928	17.515	EPSD	ICGC;COSMIC	13.948	Up-regulation
AGC_PKC_PKCh_PRKCE_ST	P40763	STAT3	Q02156	PRKCE	T412	E415K	415	Missense	distal	3	no	16.928	17.555	EPSD	ICGC;COSMIC	13.948	Up-regulation
AGC_PKC_PKCh_PRKCE_ST	P40763	STAT3	Q02156	PRKCE	S599	I597M	597	Missense	proximal	-2	no	12.216	14.431	EPSD	ICGC;COSMIC	13.948	Gain
AGC_PKC_PKCh_PRKCE_ST	P40763	STAT3	Q02156	PRKCE	S691	P689T	689	Missense	proximal	-2	no	14.277	12.628	EPSD	ICGC	13.948	Loss
AGC_PKC_PKCh_PRKCE_ST	P40763	STAT3	Q02156	PRKCE	S691	S691C	691	Missense	central	0	yes	14.277	0.000	EPSD	ICGC;COSMIC	13.948	Loss
AGC_PKC_PKCh_PRKCE_ST	P40763	STAT3	Q02156	PRKCE	S691	R688W	688	Missense	distal	-3	no	14.277	3.279	EPSD	ICGC;COSMIC;GDSC;CCLE	13.948	Loss
AGC_PKC_PKCh_PRKCE_ST	P40763	STAT3	Q02156	PRKCE	S727	L724P	724	Missense	distal	-3	no	18.269	17.115	PhosphoSitePlus	ICGC;COSMIC	13.948	Down-regulation
AGC_PKC_PKCh_PRKCE_ST	P40763	STAT3	Q02156	PRKCE	S727	S727P	727	Missense	central	0	yes	18.269	0.000	PhosphoSitePlus	ICGC	13.948	Loss
AGC_PKC_PKCh_PRKCE_ST	P40763	STAT3	Q02156	PRKCE	S727	L734S	734	Missense	distal	7	no	18.269	18.727	PhosphoSitePlus	ICGC;COSMIC	13.948	Up-regulation
AGC_PKC_PKCh_PRKCE_ST	P19429	TNNI3	Q02156	PRKCE	S23	R27S	27	Missense	distal	4	no	20.306	19.926	EPSD	ICGC	13.948	Down-regulation
AGC_PKC_PKCh_PRKCE_ST	P19429	TNNI3	Q02156	PRKCE	S23	R21S	21	Missense	proximal	-2	no	20.306	19.495	EPSD	ICGC	13.948	Down-regulation
AGC_PKC_PKCh_PRKCE_ST	P19429	TNNI3	Q02156	PRKCE	S23	S24F	24	Missense	proximal	1	no	20.306	21.642	EPSD	ICGC;COSMIC	13.948	Up-regulation
AGC_PKC_PKCh_PRKCE_ST	P19429	TNNI3	Q02156	PRKCE	S23	R21L	21	Missense	proximal	-2	no	20.306	17.202	EPSD	ICGC;COSMIC	13.948	Down-regulation
AGC_PKC_PKCh_PRKCE_ST	P19429	TNNI3	Q02156	PRKCE	S24	R27S	27	Missense	distal	3	no	17.186	16.938	EPSD	ICGC	13.948	Down-regulation
AGC_PKC_PKCh_PRKCE_ST	P19429	TNNI3	Q02156	PRKCE	S24	R21S	21	Missense	distal	-3	no	17.186	12.417	EPSD	ICGC	13.948	Loss
AGC_PKC_PKCh_PRKCE_ST	P19429	TNNI3	Q02156	PRKCE	S24	S24F	24	Missense	central	0	yes	17.186	0.000	EPSD	ICGC;COSMIC	13.948	Loss
AGC_PKC_PKCh_PRKCE_ST	P19429	TNNI3	Q02156	PRKCE	S24	R21L	21	Missense	distal	-3	no	17.186	10.254	EPSD	ICGC;COSMIC	13.948	Loss
AGC_PKC_PKCh_PRKCE_ST	P19429	TNNI3	Q02156	PRKCE	T143	R145W	145	Missense	proximal	2	no	19.722	7.049	EPSD	ICGC;COSMIC;GDSC;CCLE	13.948	Loss
AGC_PKC_PKCh_PRKCE_ST	P19429	TNNI3	Q02156	PRKCE	T181	E184K	184	Missense	distal	3	no	19.745	20.372	EPSD	ICGC;COSMIC	13.948	Up-regulation
AGC_PKC_PKCh_PRKCE_ST	P15336	ATF2	Q02156	PRKCE	S340	S340L	340	Missense	central	0	yes	17.489	0.000	EPSD	ICGC;COSMIC	13.948	Loss
AGC_PKC_PKCh_PRKCE_ST	P15336	ATF2	Q02156	PRKCE	S340	Q337H	337	Missense	distal	-3	no	17.489	17.835	EPSD	ICGC;COSMIC	13.948	Up-regulation
AGC_PKC_PKCh_PRKCE_ST	Q16612	NREP	Q02156	PRKCE	S59	R58C	58	Missense	proximal	-1	no	17.731	17.374	PhosphoSitePlus	ICGC;COSMIC	13.948	Down-regulation
AGC_PKC_PKCh_PRKCE_ST	Q16612	NREP	Q02156	PRKCE	S59	R58L	58	Missense	proximal	-1	no	17.731	16.987	PhosphoSitePlus	ICGC	13.948	Down-regulation
AGC_PKC_PKCh_PRKCE_ST	Q16612	NREP	Q02156	PRKCE	S59	G53S	53	Missense	distal	-6	no	17.731	17.713	PhosphoSitePlus	ICGC;COSMIC	13.948	Down-regulation
AGC_PKC_PKCh_PRKCE_ST	Q16612	NREP	Q02156	PRKCE	S59	R61K	61	Missense	proximal	2	no	17.731	18.412	PhosphoSitePlus	ICGC	13.948	Up-regulation
AGC_PKC_PKCh_PRKCE_ST	Q16612	NREP	Q02156	PRKCE	S59	R61I	61	Missense	proximal	2	no	17.731	10.923	PhosphoSitePlus	ICGC;COSMIC	13.948	Loss
AGC_PKC_PKCh_PRKCE_ST	Q16612	NREP	Q02156	PRKCE	S59	G53D	53	Missense	distal	-6	no	17.731	17.747	PhosphoSitePlus	ICGC	13.948	Up-regulation
AGC_PKC_PKCh_PRKCE_ST	O60716	CTNND1	Q02156	PRKCE	S252	R253H	253	Missense	proximal	1	no	15.323	12.771	EPSD	ICGC;COSMIC	13.948	Loss
AGC_PKC_PKCh_PRKCE_ST	P08581	MET	Q02156	PRKCE	S283	R277K	277	Missense	distal	-6	no	16.406	16.367	EPSD	ICGC;COSMIC	13.948	Down-regulation
AGC_PKC_PKCh_PRKCE_ST	P08581	MET	Q02156	PRKCE	S283	R280S	280	Missense	distal	-3	no	16.406	11.637	EPSD	ICGC;COSMIC	13.948	Loss
AGC_PKC_PKCh_PRKCE_ST	P08581	MET	Q02156	PRKCE	S283	S283A	283	Missense	central	0	yes	16.406	0.000	EPSD	ICGC;COSMIC	13.948	Loss
AGC_PKC_PKCh_PRKCE_ST	P08581	MET	Q02156	PRKCE	S283	R280K	280	Missense	distal	-3	no	16.406	16.424	EPSD	ICGC	13.948	Up-regulation
AGC_PKC_PKCh_PRKCE_ST	P08581	MET	Q02156	PRKCE	S283	S283F	283	Missense	central	0	yes	16.406	0.000	EPSD	ICGC	13.948	Loss
AGC_PKC_PKCh_PRKCE_ST	P08581	MET	Q02156	PRKCE	S985	R987G	987	Missense	proximal	2	no	20.739	15.827	PhosphoSitePlus	ICGC;COSMIC	13.948	Down-regulation
AGC_PKC_PKCh_PRKCE_ST	P08581	MET	Q02156	PRKCE	S985	L983H	983	Missense	proximal	-2	no	20.739	21.293	PhosphoSitePlus	ICGC;COSMIC	13.948	Up-regulation
AGC_PKC_PKCh_PRKCE_ST	P08581	MET	Q02156	PRKCE	S985	H979Y	979	Missense	distal	-6	no	20.739	20.853	PhosphoSitePlus	ICGC;COSMIC	13.948	Up-regulation
AGC_PKC_PKCh_PRKCE_ST	P08581	MET	Q02156	PRKCE	S985	R982M	982	Missense	distal	-3	no	20.739	10.519	PhosphoSitePlus	ICGC;COSMIC	13.948	Loss
AGC_PKC_PKCh_PRKCE_ST	P08581	MET	Q02156	PRKCE	S997	E994K	994	Missense	distal	-3	no	7.147	14.274	EPSD	ICGC;COSMIC	13.948	Gain
AGC_PKC_PKCh_PRKCE_ST	P08581	MET	Q02156	PRKCE	T1257	Q1258K	1258	Missense	proximal	1	no	12.165	14.390	EPSD	ICGC;COSMIC	13.948	Gain
AGC_PKC_PKCh_PRKCE_ST	P08581	MET	Q02156	PRKCE	T1261	Q1258K	1258	Missense	distal	-3	no	15.563	21.147	EPSD	ICGC;COSMIC	13.948	Up-regulation
STE_STE20_MST_STK3_ST	P17252	PRKCA	Q13188	STK3	T108	Y109F	109	Missense	proximal	1	no	59.282	91.168	EPSD	ICGC;COSMIC	55.172	Up-regulation
STE_STE20_MST_STK3_ST	P17252	PRKCA	Q13188	STK3	T176	N182I	182	Missense	distal	6	no	60.683	53.809	EPSD	ICGC;COSMIC	55.172	Loss
STE_STE20_MST_STK3_ST	P17252	PRKCA	Q13188	STK3	T218	P221L	221	Missense	distal	3	no	58.570	57.931	EPSD	ICGC	55.172	Down-regulation
STE_STE20_MST_STK3_ST	P17252	PRKCA	Q13188	STK3	S226	P221L	221	Missense	distal	-5	no	93.402	100.213	PhosphoSitePlus;EPSD	ICGC	55.172	Up-regulation
STE_STE20_MST_STK3_ST	P17252	PRKCA	Q13188	STK3	T228	P221L	221	Missense	distal	-7	no	111.878	111.483	EPSD;PhosphoSitePlus	ICGC	55.172	Down-regulation
STE_STE20_MST_STK3_ST	P17252	PRKCA	Q13188	STK3	S349	G346E	346	Missense	distal	-3	no	48.344	61.412	EPSD	ICGC	55.172	Gain
STE_STE20_MST_STK3_ST	P17252	PRKCA	Q13188	STK3	T497	T495N	495	Missense	proximal	-2	no	70.838	70.507	EPSD	ICGC;COSMIC	55.172	Down-regulation
STE_STE20_MST_STK3_ST	P17252	PRKCA	Q13188	STK3	T497	D491Y	491	Missense	distal	-6	no	70.838	71.017	EPSD	ICGC	55.172	Up-regulation
STE_STE20_MST_STK3_ST	P17252	PRKCA	Q13188	STK3	T497	T495I	495	Missense	proximal	-2	no	70.838	68.690	EPSD	ICGC	55.172	Down-regulation
STE_STE20_MST_STK3_ST	P00519	ABL1	Q13188	STK3	T243	H246Y	246	Missense	distal	3	no	65.816	63.952	EPSD	ICGC;COSMIC	55.172	Down-regulation
STE_STE20_MST_STK3_ST	P00519	ABL1	Q13188	STK3	T243	R239C	239	Missense	distal	-4	no	65.816	67.687	EPSD	ICGC;COSMIC	55.172	Up-regulation
STE_STE20_MST_STK3_ST	P00519	ABL1	Q13188	STK3	T243	R239H	239	Missense	distal	-4	no	65.816	65.561	EPSD	ICGC	55.172	Down-regulation
STE_STE20_MST_STK3_ST	P00519	ABL1	Q13188	STK3	T243	G250R	250	Missense	distal	7	no	65.816	65.093	EPSD	ICGC;COSMIC	55.172	Down-regulation
STE_STE20_MST_STK3_ST	P00519	ABL1	Q13188	STK3	T532	R533S	533	Missense	proximal	1	no	58.019	72.757	EPSD	ICGC;COSMIC	55.172	Up-regulation
STE_STE20_MST_STK3_ST	P00519	ABL1	Q13188	STK3	T532	P529S	529	Missense	distal	-3	no	58.019	60.773	EPSD	ICGC;COSMIC	55.172	Up-regulation
STE_STE20_MST_STK3_ST	P00519	ABL1	Q13188	STK3	S535	P529S	529	Missense	distal	-6	no	53.423	55.994	EPSD	ICGC;COSMIC	55.172	Gain
STE_STE20_MST_STK3_ST	P00519	ABL1	Q13188	STK3	S695	G701S	701	Missense	distal	6	no	46.912	56.022	EPSD	ICGC;CCLE	55.172	Gain
STE_STE20_MST_STK3_ST	P00519	ABL1	Q13188	STK3	S709	R712H	712	Missense	distal	3	no	54.389	55.762	EPSD	ICGC;COSMIC	55.172	Gain
STE_STE20_MST_STK3_ST	P00519	ABL1	Q13188	STK3	S709	G706S	706	Missense	distal	-3	no	54.389	61.375	EPSD	ICGC;COSMIC	55.172	Gain
STE_STE20_MST_STK3_ST	P00519	ABL1	Q13188	STK3	T735	D728Y	728	Missense	distal	-7	no	96.619	95.839	PhosphoSitePlus	ICGC	55.172	Down-regulation
STE_STE20_MST_STK3_ST	P00519	ABL1	Q13188	STK3	T735	S742F	742	Missense	distal	7	no	96.619	97.621	PhosphoSitePlus	ICGC;COSMIC	55.172	Up-regulation
STE_STE20_MST_STK3_ST	P00519	ABL1	Q13188	STK3	T751	D748Y	748	Missense	distal	-3	no	57.618	58.001	EPSD	ICGC	55.172	Up-regulation
STE_STE20_MST_STK3_ST	P00519	ABL1	Q13188	STK3	T814	P810L	810	Missense	distal	-4	no	55.272	53.816	EPSD	ICGC;COSMIC	55.172	Loss
STE_STE20_MST_STK3_ST	P00519	ABL1	Q13188	STK3	S884	P885S	885	Missense	proximal	1	no	53.039	58.295	EPSD	ICGC	55.172	Gain
STE_STE20_MST_STK3_ST	P00519	ABL1	Q13188	STK3	S917	P918L	918	Missense	proximal	1	no	40.083	58.518	EPSD	ICGC;COSMIC	55.172	Gain
STE_STE20_MST_STK3_ST	P00519	ABL1	Q13188	STK3	S989	D995E	995	Missense	distal	6	no	52.017	55.719	EPSD	ICGC	55.172	Gain
STE_STE20_MST_STK3_ST	P00519	ABL1	Q13188	STK3	S1119	S1120L	1120	Missense	proximal	1	no	50.505	63.683	EPSD	ICGC;COSMIC	55.172	Gain
STE_STE20_MST_STK3_ST	Q9H4B6	SAV1	Q13188	STK3	T26	L33R	33	Missense	distal	7	no	96.976	96.309	EPSD;PhosphoSitePlus	ICGC	55.172	Down-regulation
STE_STE20_MST_STK3_ST	Q9H4B6	SAV1	Q13188	STK3	S27	L33R	33	Missense	distal	6	no	81.901	84.985	EPSD;PhosphoSitePlus	ICGC	55.172	Up-regulation
STE_STE20_MST_STK3_ST	Q9H4B6	SAV1	Q13188	STK3	S36	L33R	33	Missense	distal	-3	no	94.363	92.030	PhosphoSitePlus;EPSD	ICGC	55.172	Down-regulation
STE_STE20_MST_STK3_ST	Q9H4B6	SAV1	Q13188	STK3	S269	Y262H	262	Missense	distal	-7	no	93.324	93.556	EPSD;PhosphoSitePlus	ICGC;COSMIC	55.172	Up-regulation
STE_STE20_MST_STK3_ST	Q9H4B6	SAV1	Q13188	STK3	S269	P271T	271	Missense	proximal	2	no	93.324	93.597	EPSD;PhosphoSitePlus	ICGC	55.172	Up-regulation
STE_STE20_MST_STK3_ST	Q9H4B6	SAV1	Q13188	STK3	S269	H264N	264	Missense	distal	-5	no	93.324	92.711	EPSD;PhosphoSitePlus	ICGC	55.172	Down-regulation
STE_STE20_MST_STK3_ST	Q9H4B6	SAV1	Q13188	STK3	S269	Y273H	273	Missense	distal	4	no	93.324	93.754	EPSD;PhosphoSitePlus	ICGC;COSMIC	55.172	Up-regulation
STE_STE20_MST_STK3_ST	Q9H8S9	MOB1A	Q13188	STK3	T35	T35N	35	Missense	central	0	yes	95.972	0.000	PhosphoSitePlus;EPSD	ICGC	55.172	Loss
STE_STE20_MST_STK3_ST	Q9H8S9	MOB1A	Q13188	STK3	T74	M70L	70	Missense	distal	-4	no	99.340	98.961	EPSD;PhosphoSitePlus	ICGC;COSMIC	55.172	Down-regulation
STE_STE20_MST_STK3_ST	Q9H8S9	MOB1A	Q13188	STK3	T74	M70V	70	Missense	distal	-4	no	99.340	99.293	EPSD;PhosphoSitePlus	ICGC;COSMIC	55.172	Down-regulation
STE_STE20_MST_STK3_ST	P51955	NEK2	Q13188	STK3	T175	D169E	169	Missense	distal	-6	no	62.472	65.987	EPSD	ICGC	55.172	Up-regulation
STE_STE20_MST_STK3_ST	P51955	NEK2	Q13188	STK3	S356	N354S	354	Missense	proximal	-2	no	91.920	91.116	EPSD;PhosphoSitePlus	ICGC;COSMIC	55.172	Down-regulation
STE_STE20_MST_STK3_ST	P51955	NEK2	Q13188	STK3	S356	R361Q	361	Missense	distal	5	no	91.920	90.422	EPSD;PhosphoSitePlus	ICGC;COSMIC	55.172	Down-regulation
STE_STE20_MST_STK3_ST	P51955	NEK2	Q13188	STK3	S356	N354K	354	Missense	proximal	-2	no	91.920	94.230	EPSD;PhosphoSitePlus	ICGC	55.172	Up-regulation
STE_STE20_MST_STK3_ST	P51955	NEK2	Q13188	STK3	S365	R361Q	361	Missense	distal	-4	no	107.348	107.506	EPSD;PhosphoSitePlus	ICGC;COSMIC	55.172	Up-regulation
STE_STE20_MST_STK3_ST	P51955	NEK2	Q13188	STK3	S365	S365P	365	Missense	central	0	yes	107.348	0.000	EPSD;PhosphoSitePlus	ICGC	55.172	Loss
STE_STE20_MST_STK3_ST	O95835	LATS1	Q13188	STK3	T17	T17N	17	Missense	central	0	yes	66.640	0.000	EPSD	ICGC	55.172	Loss
STE_STE20_MST_STK3_ST	O95835	LATS1	Q13188	STK3	T17	R11K	11	Missense	distal	-6	no	66.640	70.113	EPSD	ICGC;COSMIC	55.172	Up-regulation
STE_STE20_MST_STK3_ST	O95835	LATS1	Q13188	STK3	S27	M30I	30	Missense	distal	3	no	56.802	59.350	EPSD	ICGC;COSMIC	55.172	Up-regulation
STE_STE20_MST_STK3_ST	O95835	LATS1	Q13188	STK3	S404	S399L	399	Missense	distal	-5	no	61.600	65.957	EPSD	ICGC;COSMIC;GDSC;CCLE	55.172	Up-regulation
STE_STE20_MST_STK3_ST	O95835	LATS1	Q13188	STK3	S872	Q870H	870	Missense	proximal	-2	no	89.781	90.344	EPSD;PhosphoSitePlus	ICGC;COSMIC	55.172	Up-regulation
STE_STE20_MST_STK3_ST	O95835	LATS1	Q13188	STK3	S883	D889G	889	Missense	distal	6	no	55.923	55.906	EPSD	ICGC;COSMIC	55.172	Down-regulation
STE_STE20_MST_STK3_ST	O95835	LATS1	Q13188	STK3	S883	R890I	890	Missense	distal	7	no	55.923	56.590	EPSD	ICGC;COSMIC	55.172	Up-regulation
STE_STE20_MST_STK3_ST	O95835	LATS1	Q13188	STK3	S909	H902N	902	Missense	distal	-7	no	108.035	107.281	PhosphoSitePlus;EPSD	ICGC	55.172	Down-regulation
STE_STE20_MST_STK3_ST	O95835	LATS1	Q13188	STK3	S909	S909F	909	Missense	central	0	yes	108.035	0.000	PhosphoSitePlus;EPSD	ICGC;COSMIC	55.172	Loss
STE_STE20_MST_STK3_ST	O95835	LATS1	Q13188	STK3	S909	T913I	913	Missense	distal	4	no	108.035	109.347	PhosphoSitePlus;EPSD	ICGC;COSMIC	55.172	Up-regulation
STE_STE20_MST_STK3_ST	O95835	LATS1	Q13188	STK3	T967	W965C	965	Missense	proximal	-2	no	92.439	91.777	EPSD;PhosphoSitePlus	ICGC;COSMIC	55.172	Down-regulation
STE_STE20_MST_STK3_ST	O95835	LATS1	Q13188	STK3	T1012	F1010L	1010	Missense	proximal	-2	no	96.824	98.692	EPSD;PhosphoSitePlus	ICGC;COSMIC	55.172	Up-regulation
STE_STE20_MST_STK3_ST	O95835	LATS1	Q13188	STK3	T1012	A1006D	1006	Missense	distal	-6	no	96.824	96.303	EPSD;PhosphoSitePlus	ICGC	55.172	Down-regulation
STE_STE20_MST_STK3_ST	O95835	LATS1	Q13188	STK3	T1079	E1072G	1072	Missense	distal	-7	no	94.072	94.566	EPSD;PhosphoSitePlus	ICGC	55.172	Up-regulation
STE_STE20_MST_STK3_ST	O95835	LATS1	Q13188	STK3	T1079	R1082M	1082	Missense	distal	3	no	94.072	92.335	EPSD;PhosphoSitePlus	ICGC	55.172	Down-regulation
STE_STE20_MST_STK3_ST	O95835	LATS1	Q13188	STK3	T1079	A1074E	1074	Missense	distal	-5	no	94.072	102.923	EPSD;PhosphoSitePlus	ICGC	55.172	Up-regulation
STE_STE20_MST_STK3_ST	Q13188	STK3	Q13188	STK3	S18	E25K	25	Missense	distal	7	no	63.339	60.403	EPSD	ICGC	55.172	Down-regulation
STE_STE20_MST_STK3_ST	Q13188	STK3	Q13188	STK3	S333	R338W	338	Missense	distal	5	no	58.060	58.692	EPSD	ICGC;COSMIC;CCLE	55.172	Up-regulation
STE_STE20_MST_STK3_ST	Q13188	STK3	Q13188	STK3	S333	G335D	335	Missense	proximal	2	no	58.060	58.096	EPSD	ICGC;COSMIC	55.172	Up-regulation
STE_STE20_MST_STK3_ST	Q13188	STK3	Q13188	STK3	S333	R338Q	338	Missense	distal	5	no	58.060	56.563	EPSD	ICGC	55.172	Down-regulation
STE_STE20_MST_STK3_ST	Q13188	STK3	Q13188	STK3	S333	M326L	326	Missense	distal	-7	no	58.060	58.048	EPSD	ICGC;COSMIC	55.172	Down-regulation
STE_STE20_MST_STK3_ST	Q13188	STK3	Q13188	STK3	S333	R338L	338	Missense	distal	5	no	58.060	58.133	EPSD	ICGC;COSMIC	55.172	Up-regulation
STE_STE20_MST_STK3_ST	Q13188	STK3	Q13188	STK3	T364	E370D	370	Missense	distal	6	no	63.595	59.894	EPSD	ICGC;COSMIC	55.172	Down-regulation
STE_STE20_MST_STK3_ST	Q13188	STK3	Q13188	STK3	T364	M357I	357	Missense	distal	-7	no	63.595	63.815	EPSD	ICGC;COSMIC	55.172	Up-regulation
STE_STE20_MST_STK3_ST	Q13188	STK3	Q13188	STK3	T378	M379T	379	Missense	proximal	1	no	104.081	86.774	EPSD;PhosphoSitePlus	ICGC;COSMIC	55.172	Down-regulation
STE_STE20_MST_STK3_ST	Q13188	STK3	Q13188	STK3	T378	M379I	379	Missense	proximal	1	no	104.081	110.136	EPSD;PhosphoSitePlus	ICGC	55.172	Up-regulation
STE_STE20_MST_STK3_ST	P46937	YAP1	Q13188	STK3	S105	P99Q	99	Missense	distal	-6	no	53.818	57.380	EPSD	ICGC;COSMIC	55.172	Gain
STE_STE20_MST_STK3_ST	P46937	YAP1	Q13188	STK3	S127	Q133L	133	Missense	distal	6	no	88.207	80.636	PhosphoSitePlus	ICGC;COSMIC	55.172	Down-regulation
STE_STE20_MST_STK3_ST	P46937	YAP1	Q13188	STK3	S127	V123F	123	Missense	distal	-4	no	88.207	90.872	PhosphoSitePlus	ICGC	55.172	Up-regulation
STE_STE20_MST_STK3_ST	P46937	YAP1	Q13188	STK3	S127	L134F	134	Missense	distal	7	no	88.207	86.613	PhosphoSitePlus	ICGC;COSMIC	55.172	Down-regulation
STE_STE20_MST_STK3_ST	P46937	YAP1	Q13188	STK3	S127	H126R	126	Missense	proximal	-1	no	88.207	86.721	PhosphoSitePlus	ICGC;COSMIC	55.172	Down-regulation
STE_STE20_MST_STK3_ST	P46937	YAP1	Q13188	STK3	S131	Q133L	133	Missense	proximal	2	no	59.720	60.729	EPSD	ICGC;COSMIC	55.172	Up-regulation
STE_STE20_MST_STK3_ST	P46937	YAP1	Q13188	STK3	S131	V137F	137	Missense	distal	6	no	59.720	55.533	EPSD	ICGC;COSMIC	55.172	Down-regulation
STE_STE20_MST_STK3_ST	P46937	YAP1	Q13188	STK3	S131	L134F	134	Missense	distal	3	no	59.720	61.239	EPSD	ICGC;COSMIC	55.172	Up-regulation
STE_STE20_MST_STK3_ST	P46937	YAP1	Q13188	STK3	S131	H126R	126	Missense	distal	-5	no	59.720	56.368	EPSD	ICGC;COSMIC	55.172	Down-regulation
STE_STE20_MST_STK3_ST	P46937	YAP1	Q13188	STK3	S274	A268P	268	Missense	distal	-6	no	56.361	55.558	EPSD	ICGC;COSMIC	55.172	Down-regulation
STE_STE20_MST_STK3_ST	P46937	YAP1	Q13188	STK3	S274	R272G	272	Missense	proximal	-2	no	56.361	53.634	EPSD	ICGC;COSMIC	55.172	Loss
STE_STE20_MST_STK3_ST	P46937	YAP1	Q13188	STK3	T361	G359C	359	Missense	proximal	-2	no	59.163	58.502	EPSD	ICGC	55.172	Down-regulation
Atypical_PIKK_ATR_ATR_ST	O60934	NBN	Q13535	ATR	S58	F52L	52	Missense	distal	-6	no	11.537	11.567	EPSD	ICGC;COSMIC	10.658	Up-regulation
Atypical_PIKK_ATR_ATR_ST	O60934	NBN	Q13535	ATR	S58	S53Y	53	Missense	distal	-5	no	11.537	11.864	EPSD	ICGC	10.658	Up-regulation
Atypical_PIKK_ATR_ATR_ST	O60934	NBN	Q13535	ATR	T60	S53Y	53	Missense	distal	-7	no	11.017	10.844	EPSD	ICGC	10.658	Down-regulation
Atypical_PIKK_ATR_ATR_ST	O60934	NBN	Q13535	ATR	S278	T280K	280	Missense	proximal	2	no	15.706	16.217	EPSD	ICGC	10.658	Up-regulation
Atypical_PIKK_ATR_ATR_ST	O60934	NBN	Q13535	ATR	S278	N277K	277	Missense	proximal	-1	no	15.706	15.122	EPSD	ICGC	10.658	Down-regulation
Atypical_PIKK_ATR_ATR_ST	O60934	NBN	Q13535	ATR	S738	D742V	742	Missense	distal	4	no	10.457	10.672	EPSD	ICGC;COSMIC	10.658	Gain
Atypical_PIKK_ATR_ATR_ST	P78527	PRKDC	Q13535	ATR	S237	Q243R	243	Missense	distal	6	no	13.188	12.920	EPSD	ICGC	10.658	Down-regulation
Atypical_PIKK_ATR_ATR_ST	P78527	PRKDC	Q13535	ATR	S237	M238V	238	Missense	proximal	1	no	13.188	-2.421	EPSD	ICGC;COSMIC;GDSC	10.658	Loss
Atypical_PIKK_ATR_ATR_ST	P78527	PRKDC	Q13535	ATR	S245	Q243R	243	Missense	proximal	-2	no	11.126	11.205	EPSD	ICGC	10.658	Up-regulation
Atypical_PIKK_ATR_ATR_ST	P78527	PRKDC	Q13535	ATR	S245	M238V	238	Missense	distal	-7	no	11.126	11.083	EPSD	ICGC;COSMIC;GDSC	10.658	Down-regulation
Atypical_PIKK_ATR_ATR_ST	P78527	PRKDC	Q13535	ATR	S245	N250Y	250	Missense	distal	5	no	11.126	11.143	EPSD	ICGC;COSMIC	10.658	Up-regulation
Atypical_PIKK_ATR_ATR_ST	P78527	PRKDC	Q13535	ATR	S318	Q322L	322	Missense	distal	4	no	12.371	12.722	EPSD	ICGC;COSMIC	10.658	Up-regulation
Atypical_PIKK_ATR_ATR_ST	P78527	PRKDC	Q13535	ATR	S318	Q322H	322	Missense	distal	4	no	12.371	12.083	EPSD	ICGC;COSMIC	10.658	Down-regulation
Atypical_PIKK_ATR_ATR_ST	P78527	PRKDC	Q13535	ATR	T398	K393N	393	Missense	distal	-5	no	10.585	10.731	EPSD	ICGC;COSMIC	10.658	Gain
Atypical_PIKK_ATR_ATR_ST	P78527	PRKDC	Q13535	ATR	S922	Q925K	925	Missense	distal	3	no	11.243	11.516	EPSD	ICGC	10.658	Up-regulation
Atypical_PIKK_ATR_ATR_ST	P78527	PRKDC	Q13535	ATR	S922	A921D	921	Missense	proximal	-1	no	11.243	11.154	EPSD	ICGC	10.658	Down-regulation
Atypical_PIKK_ATR_ATR_ST	P78527	PRKDC	Q13535	ATR	S936	L933R	933	Missense	distal	-3	no	11.550	11.516	EPSD	ICGC	10.658	Down-regulation
Atypical_PIKK_ATR_ATR_ST	P78527	PRKDC	Q13535	ATR	T1793	R1787S	1787	Missense	distal	-6	no	13.596	13.514	EPSD	ICGC	10.658	Down-regulation
Atypical_PIKK_ATR_ATR_ST	P78527	PRKDC	Q13535	ATR	T3599	K3603Q	3603	Missense	distal	4	no	10.878	10.896	EPSD	ICGC	10.658	Up-regulation
Atypical_PIKK_ATR_ATR_ST	Q99708	RBBP8	Q13535	ATR	S10	S10I	10	Missense	central	0	yes	11.057	0.000	EPSD	ICGC;COSMIC	10.658	Loss
Atypical_PIKK_ATR_ATR_ST	Q99708	RBBP8	Q13535	ATR	S10	A14S	14	Missense	distal	4	no	11.057	10.755	EPSD	ICGC	10.658	Down-regulation
Atypical_PIKK_ATR_ATR_ST	Q99708	RBBP8	Q13535	ATR	S10	S6N	6	Missense	distal	-4	no	11.057	11.280	EPSD	ICGC;COSMIC	10.658	Up-regulation
Atypical_PIKK_ATR_ATR_ST	Q99708	RBBP8	Q13535	ATR	T16	S10I	10	Missense	distal	-6	no	10.727	10.811	EPSD	ICGC;COSMIC	10.658	Up-regulation
Atypical_PIKK_ATR_ATR_ST	Q99708	RBBP8	Q13535	ATR	T16	A14S	14	Missense	proximal	-2	no	10.727	9.952	EPSD	ICGC	10.658	Loss
Atypical_PIKK_ATR_ATR_ST	Q99708	RBBP8	Q13535	ATR	S163	P164Q	164	Missense	proximal	1	no	6.781	11.649	EPSD	ICGC;COSMIC	10.658	Gain
Atypical_PIKK_ATR_ATR_ST	Q99708	RBBP8	Q13535	ATR	S231	D226E	226	Missense	distal	-5	no	15.119	14.867	EPSD	ICGC;COSMIC	10.658	Down-regulation
Atypical_PIKK_ATR_ATR_ST	Q99708	RBBP8	Q13535	ATR	S231	T227I	227	Missense	distal	-4	no	15.119	13.864	EPSD	ICGC	10.658	Down-regulation
Atypical_PIKK_ATR_ATR_ST	Q99708	RBBP8	Q13535	ATR	S231	M235I	235	Missense	distal	4	no	15.119	16.247	EPSD	ICGC;COSMIC	10.658	Up-regulation
Atypical_PIKK_ATR_ATR_ST	Q99708	RBBP8	Q13535	ATR	S231	S231I	231	Missense	central	0	yes	15.119	0.000	EPSD	ICGC	10.658	Loss
Atypical_PIKK_ATR_ATR_ST	Q99708	RBBP8	Q13535	ATR	T241	S243I	243	Missense	proximal	2	no	11.558	10.885	EPSD	ICGC;COSMIC	10.658	Down-regulation
Atypical_PIKK_ATR_ATR_ST	Q99708	RBBP8	Q13535	ATR	T241	M235I	235	Missense	distal	-6	no	11.558	11.578	EPSD	ICGC;COSMIC	10.658	Up-regulation
Atypical_PIKK_ATR_ATR_ST	Q99708	RBBP8	Q13535	ATR	S439	E435D	435	Missense	distal	-4	no	13.000	12.818	EPSD	ICGC;COSMIC	10.658	Down-regulation
Atypical_PIKK_ATR_ATR_ST	Q99708	RBBP8	Q13535	ATR	S555	S555A	555	Missense	central	0	yes	15.106	0.000	EPSD	ICGC	10.658	Loss
Atypical_PIKK_ATR_ATR_ST	Q99708	RBBP8	Q13535	ATR	S555	P550S	550	Missense	distal	-5	no	15.106	15.076	EPSD	ICGC	10.658	Down-regulation
Atypical_PIKK_ATR_ATR_ST	Q99708	RBBP8	Q13535	ATR	S555	G551W	551	Missense	distal	-4	no	15.106	15.783	EPSD	ICGC;COSMIC	10.658	Up-regulation
Atypical_PIKK_ATR_ATR_ST	Q99708	RBBP8	Q13535	ATR	S593	V599F	599	Missense	distal	6	no	11.000	10.955	EPSD	ICGC;COSMIC	10.658	Down-regulation
Atypical_PIKK_ATR_ATR_ST	Q99708	RBBP8	Q13535	ATR	S593	P590L	590	Missense	distal	-3	no	11.000	11.295	EPSD	ICGC	10.658	Up-regulation
Atypical_PIKK_ATR_ATR_ST	Q99708	RBBP8	Q13535	ATR	T596	V599F	599	Missense	distal	3	no	11.187	10.056	EPSD	ICGC;COSMIC	10.658	Loss
Atypical_PIKK_ATR_ATR_ST	Q99708	RBBP8	Q13535	ATR	T596	P590L	590	Missense	distal	-6	no	11.187	11.251	EPSD	ICGC	10.658	Up-regulation
Atypical_PIKK_ATR_ATR_ST	Q99708	RBBP8	Q13535	ATR	S679	K682Q	682	Missense	distal	3	no	13.465	13.191	EPSD	ICGC;COSMIC	10.658	Down-regulation
Atypical_PIKK_ATR_ATR_ST	Q99708	RBBP8	Q13535	ATR	S679	D674Y	674	Missense	distal	-5	no	13.465	13.624	EPSD	ICGC	10.658	Up-regulation
Atypical_PIKK_ATR_ATR_ST	Q99708	RBBP8	Q13535	ATR	S679	G678D	678	Missense	proximal	-1	no	13.465	13.558	EPSD	ICGC;COSMIC	10.658	Up-regulation
Atypical_PIKK_ATR_ATR_ST	Q99708	RBBP8	Q13535	ATR	T859	S858F	858	Missense	proximal	-1	no	15.375	15.377	PhosphoSitePlus	ICGC;COSMIC	10.658	Up-regulation
Atypical_PIKK_ATR_ATR_ST	Q99708	RBBP8	Q13535	ATR	T859	R865G	865	Missense	distal	6	no	15.375	15.529	PhosphoSitePlus	ICGC;COSMIC	10.658	Up-regulation
Atypical_PIKK_ATR_ATR_ST	Q99708	RBBP8	Q13535	ATR	T859	G866D	866	Missense	distal	7	no	15.375	15.566	PhosphoSitePlus	ICGC	10.658	Up-regulation
Atypical_PIKK_ATR_ATR_ST	Q9UPV0	CEP164	Q13535	ATR	S186	M183K	183	Missense	distal	-3	no	16.460	16.369	PhosphoSitePlus	ICGC;COSMIC;GDSC	10.658	Down-regulation
Atypical_PIKK_ATR_ATR_ST	Q9UPV0	CEP164	Q13535	ATR	S186	G188C	188	Missense	proximal	2	no	16.460	13.837	PhosphoSitePlus	ICGC;COSMIC	10.658	Down-regulation
Atypical_PIKK_ATR_ATR_ST	Q9UPV0	CEP164	Q13535	ATR	S234	H232R	232	Missense	proximal	-2	no	11.289	11.734	EPSD	ICGC;COSMIC;GDSC;CCLE	10.658	Up-regulation
Atypical_PIKK_ATR_ATR_ST	Q9UPV0	CEP164	Q13535	ATR	S273	G277C	277	Missense	distal	4	no	12.782	12.702	EPSD	ICGC;COSMIC	10.658	Down-regulation
Atypical_PIKK_ATR_ATR_ST	Q9UPV0	CEP164	Q13535	ATR	S319	C324W	324	Missense	distal	5	no	10.968	10.953	EPSD	ICGC;COSMIC	10.658	Down-regulation
Atypical_PIKK_ATR_ATR_ST	Q9UPV0	CEP164	Q13535	ATR	S319	E314Q	314	Missense	distal	-5	no	10.968	11.141	EPSD	ICGC;COSMIC	10.658	Up-regulation
Atypical_PIKK_ATR_ATR_ST	Q9UPV0	CEP164	Q13535	ATR	T329	A332S	332	Missense	distal	3	no	9.997	10.658	EPSD	ICGC;COSMIC	10.658	Gain
Atypical_PIKK_ATR_ATR_ST	Q9UPV0	CEP164	Q13535	ATR	S383	S379G	379	Missense	distal	-4	no	14.812	14.295	EPSD	ICGC;COSMIC	10.658	Down-regulation
Atypical_PIKK_ATR_ATR_ST	Q9UPV0	CEP164	Q13535	ATR	S452	D451Y	451	Missense	proximal	-1	no	15.831	15.975	EPSD	ICGC	10.658	Up-regulation
Atypical_PIKK_ATR_ATR_ST	Q9UPV0	CEP164	Q13535	ATR	S455	D451Y	451	Missense	distal	-4	no	13.687	10.460	EPSD	ICGC	10.658	Loss
Atypical_PIKK_ATR_ATR_ST	Q9UPV0	CEP164	Q13535	ATR	S472	L467P	467	Missense	distal	-5	no	13.499	13.346	EPSD	ICGC;COSMIC	10.658	Down-regulation
Atypical_PIKK_ATR_ATR_ST	Q9UPV0	CEP164	Q13535	ATR	S472	H477R	477	Missense	distal	5	no	13.499	13.504	EPSD	ICGC;COSMIC	10.658	Up-regulation
Atypical_PIKK_ATR_ATR_ST	Q9UPV0	CEP164	Q13535	ATR	S531	E527D	527	Missense	distal	-4	no	11.636	11.454	EPSD	ICGC	10.658	Down-regulation
Atypical_PIKK_ATR_ATR_ST	Q9UPV0	CEP164	Q13535	ATR	S531	C536W	536	Missense	distal	5	no	11.636	11.621	EPSD	ICGC;COSMIC	10.658	Down-regulation
Atypical_PIKK_ATR_ATR_ST	Q9UPV0	CEP164	Q13535	ATR	S544	H543Q	543	Missense	proximal	-1	no	11.835	11.871	EPSD	ICGC;COSMIC	10.658	Up-regulation
Atypical_PIKK_ATR_ATR_ST	Q9UPV0	CEP164	Q13535	ATR	S544	K540N	540	Missense	distal	-4	no	11.835	11.454	EPSD	ICGC;COSMIC	10.658	Down-regulation
Atypical_PIKK_ATR_ATR_ST	Q9UPV0	CEP164	Q13535	ATR	S566	V571F	571	Missense	distal	5	no	10.902	10.912	EPSD	ICGC;COSMIC	10.658	Up-regulation
Atypical_PIKK_ATR_ATR_ST	Q9UPV0	CEP164	Q13535	ATR	S566	P569Q	569	Missense	distal	3	no	10.902	10.535	EPSD	ICGC;COSMIC	10.658	Loss
Atypical_PIKK_ATR_ATR_ST	Q9UPV0	CEP164	Q13535	ATR	T568	P569Q	569	Missense	proximal	1	no	6.606	11.473	EPSD	ICGC;COSMIC	10.658	Gain
Atypical_PIKK_ATR_ATR_ST	Q9UPV0	CEP164	Q13535	ATR	S572	V571F	571	Missense	proximal	-1	no	10.740	10.722	EPSD	ICGC;COSMIC	10.658	Down-regulation
Atypical_PIKK_ATR_ATR_ST	Q9UPV0	CEP164	Q13535	ATR	S572	E574D	574	Missense	proximal	2	no	10.740	9.064	EPSD	ICGC;COSMIC	10.658	Loss
Atypical_PIKK_ATR_ATR_ST	Q9UPV0	CEP164	Q13535	ATR	S572	P569Q	569	Missense	distal	-3	no	10.740	10.816	EPSD	ICGC;COSMIC	10.658	Up-regulation
Atypical_PIKK_ATR_ATR_ST	Q9UPV0	CEP164	Q13535	ATR	S646	L644I	644	Missense	proximal	-2	no	11.262	11.057	EPSD	ICGC;COSMIC	10.658	Down-regulation
Atypical_PIKK_ATR_ATR_ST	Q9UPV0	CEP164	Q13535	ATR	S834	L836M	836	Missense	proximal	2	no	9.880	11.252	EPSD	ICGC	10.658	Gain
Atypical_PIKK_ATR_ATR_ST	Q9UPV0	CEP164	Q13535	ATR	S1083	K1086R	1086	Missense	distal	3	no	12.906	12.628	EPSD	ICGC;COSMIC	10.658	Down-regulation
Atypical_PIKK_ATR_ATR_ST	Q9UPV0	CEP164	Q13535	ATR	S1273	L1279I	1279	Missense	distal	6	no	12.654	12.606	EPSD	ICGC;COSMIC	10.658	Down-regulation
Atypical_PIKK_ATR_ATR_ST	Q9UPV0	CEP164	Q13535	ATR	S1273	L1279F	1279	Missense	distal	6	no	12.654	12.721	EPSD	ICGC	10.658	Up-regulation
Atypical_PIKK_ATR_ATR_ST	Q9UPV0	CEP164	Q13535	ATR	S1273	S1267F	1267	Missense	distal	-6	no	12.654	12.734	EPSD	ICGC	10.658	Up-regulation
Atypical_PIKK_ATR_ATR_ST	Q9UPV0	CEP164	Q13535	ATR	S1273	S1280N	1280	Missense	distal	7	no	12.654	13.036	EPSD	ICGC	10.658	Up-regulation
Atypical_PIKK_ATR_ATR_ST	Q9UPV0	CEP164	Q13535	ATR	T1441	Q1446H	1446	Missense	distal	5	no	11.043	11.047	EPSD	ICGC	10.658	Up-regulation
Atypical_PIKK_ATR_ATR_ST	Q9UPV0	CEP164	Q13535	ATR	T1441	Q1446R	1446	Missense	distal	5	no	11.043	11.052	EPSD	ICGC;COSMIC	10.658	Up-regulation
Atypical_PIKK_ATR_ATR_ST	Q9UPV0	CEP164	Q13535	ATR	S1443	Q1446H	1446	Missense	distal	3	no	11.513	11.916	EPSD	ICGC	10.658	Up-regulation
Atypical_PIKK_ATR_ATR_ST	Q9UPV0	CEP164	Q13535	ATR	S1443	Q1446R	1446	Missense	distal	3	no	11.513	11.508	EPSD	ICGC;COSMIC	10.658	Down-regulation
Atypical_PIKK_ATR_ATR_ST	Q8WXE1	ATRIP	Q13535	ATR	T4	T4A	4	Missense	central	0	yes	10.771	0.000	EPSD	ICGC;COSMIC	10.658	Loss
Atypical_PIKK_ATR_ATR_ST	Q8WXE1	ATRIP	Q13535	ATR	T4	G3V	3	Missense	proximal	-1	no	10.771	10.698	EPSD	ICGC;COSMIC	10.658	Down-regulation
Atypical_PIKK_ATR_ATR_ST	Q8WXE1	ATRIP	Q13535	ATR	S68	S72I	72	Missense	distal	4	no	16.399	17.081	PhosphoSitePlus;EPSD	ICGC	10.658	Up-regulation
Atypical_PIKK_ATR_ATR_ST	Q8WXE1	ATRIP	Q13535	ATR	S68	S72R	72	Missense	distal	4	no	16.399	16.451	PhosphoSitePlus;EPSD	ICGC	10.658	Up-regulation
Atypical_PIKK_ATR_ATR_ST	Q8WXE1	ATRIP	Q13535	ATR	S68	S72T	72	Missense	distal	4	no	16.399	16.450	PhosphoSitePlus;EPSD	ICGC;COSMIC	10.658	Up-regulation
Atypical_PIKK_ATR_ATR_ST	Q8WXE1	ATRIP	Q13535	ATR	S68	L66I	66	Missense	proximal	-2	no	16.399	16.193	PhosphoSitePlus;EPSD	ICGC;COSMIC	10.658	Down-regulation
Atypical_PIKK_ATR_ATR_ST	Q8WXE1	ATRIP	Q13535	ATR	S72	A76T	76	Missense	distal	4	no	15.127	14.876	EPSD;PhosphoSitePlus	ICGC;COSMIC	10.658	Down-regulation
Atypical_PIKK_ATR_ATR_ST	Q8WXE1	ATRIP	Q13535	ATR	S72	S72I	72	Missense	central	0	yes	15.127	0.000	EPSD;PhosphoSitePlus	ICGC	10.658	Loss
Atypical_PIKK_ATR_ATR_ST	Q8WXE1	ATRIP	Q13535	ATR	S72	S72R	72	Missense	central	0	yes	15.127	0.000	EPSD;PhosphoSitePlus	ICGC	10.658	Loss
Atypical_PIKK_ATR_ATR_ST	Q8WXE1	ATRIP	Q13535	ATR	S72	L66I	66	Missense	distal	-6	no	15.127	15.101	EPSD;PhosphoSitePlus	ICGC;COSMIC	10.658	Down-regulation
Atypical_PIKK_ATR_ATR_ST	P42771	CDKN2A	Q13535	ATR	S7	E10K	10	Missense	distal	3	no	13.128	13.285	EPSD;PhosphoSitePlus	ICGC;COSMIC	10.658	Up-regulation
Atypical_PIKK_ATR_ATR_ST	P42771	CDKN2A	Q13535	ATR	S8	E10K	10	Missense	proximal	2	no	14.293	13.344	EPSD;PhosphoSitePlus	ICGC;COSMIC	10.658	Down-regulation
Atypical_PIKK_ATR_ATR_ST	P23508	MCC	Q13535	ATR	S118	S115L	115	Missense	distal	-3	no	10.340	10.911	EPSD;PhosphoSitePlus	ICGC;COSMIC	10.658	Gain
Atypical_PIKK_ATR_ATR_ST	P23508	MCC	Q13535	ATR	S118	E116A	116	Missense	proximal	-2	no	10.340	10.819	EPSD;PhosphoSitePlus	ICGC;COSMIC	10.658	Gain
Atypical_PIKK_ATR_ATR_ST	P23508	MCC	Q13535	ATR	S118	H122N	122	Missense	distal	4	no	10.340	11.379	EPSD;PhosphoSitePlus	ICGC	10.658	Gain
Atypical_PIKK_ATR_ATR_ST	P23508	MCC	Q13535	ATR	S120	N125Y	125	Missense	distal	5	no	15.800	15.817	PhosphoSitePlus;EPSD	ICGC;COSMIC	10.658	Up-regulation
Atypical_PIKK_ATR_ATR_ST	P23508	MCC	Q13535	ATR	S120	E123D	123	Missense	distal	3	no	15.800	15.690	PhosphoSitePlus;EPSD	ICGC;COSMIC	10.658	Down-regulation
Atypical_PIKK_ATR_ATR_ST	P23508	MCC	Q13535	ATR	S120	S115L	115	Missense	distal	-5	no	15.800	15.982	PhosphoSitePlus;EPSD	ICGC;COSMIC	10.658	Up-regulation
Atypical_PIKK_ATR_ATR_ST	P23508	MCC	Q13535	ATR	S120	E116A	116	Missense	distal	-4	no	15.800	15.307	PhosphoSitePlus;EPSD	ICGC;COSMIC	10.658	Down-regulation
Atypical_PIKK_ATR_ATR_ST	P23508	MCC	Q13535	ATR	S120	H122N	122	Missense	proximal	2	no	15.800	16.619	PhosphoSitePlus;EPSD	ICGC	10.658	Up-regulation
Atypical_PIKK_ATR_ATR_ST	P23508	MCC	Q13535	ATR	S120	Q119K	119	Missense	proximal	-1	no	15.800	15.636	PhosphoSitePlus;EPSD	ICGC	10.658	Down-regulation
Atypical_PIKK_ATR_ATR_ST	P23508	MCC	Q13535	ATR	S120	E126K	126	Missense	distal	6	no	15.800	15.600	PhosphoSitePlus;EPSD	ICGC;COSMIC	10.658	Down-regulation
Atypical_PIKK_ATR_ATR_ST	P23508	MCC	Q13535	ATR	S128	R129Q	129	Missense	proximal	1	no	4.912	11.907	EPSD	ICGC;COSMIC	10.658	Gain
Atypical_PIKK_ATR_ATR_ST	P23508	MCC	Q13535	ATR	S179	S179R	179	Missense	central	0	yes	12.201	0.000	EPSD	ICGC	10.658	Loss
Atypical_PIKK_ATR_ATR_ST	P23508	MCC	Q13535	ATR	S179	G175V	175	Missense	distal	-4	no	12.201	12.250	EPSD	ICGC;COSMIC	10.658	Up-regulation
Atypical_PIKK_ATR_ATR_ST	P23508	MCC	Q13535	ATR	S179	C174Y	174	Missense	distal	-5	no	12.201	12.339	EPSD	ICGC;COSMIC	10.658	Up-regulation
Atypical_PIKK_ATR_ATR_ST	P23508	MCC	Q13535	ATR	S182	S179R	179	Missense	distal	-3	no	10.525	11.062	EPSD	ICGC	10.658	Gain
Atypical_PIKK_ATR_ATR_ST	P23508	MCC	Q13535	ATR	S315	L312M	312	Missense	distal	-3	no	11.613	11.056	EPSD	ICGC	10.658	Down-regulation
Atypical_PIKK_ATR_ATR_ST	P23508	MCC	Q13535	ATR	S412	K411R	411	Missense	proximal	-1	no	15.876	16.110	EPSD	ICGC;COSMIC	10.658	Up-regulation
Atypical_PIKK_ATR_ATR_ST	P23508	MCC	Q13535	ATR	S426	E429K	429	Missense	distal	3	no	11.528	11.685	EPSD	ICGC;COSMIC	10.658	Up-regulation
Atypical_PIKK_ATR_ATR_ST	P23508	MCC	Q13535	ATR	T496	Q497K	497	Missense	proximal	1	no	14.736	3.770	EPSD	ICGC;COSMIC	10.658	Loss
Atypical_PIKK_ATR_ATR_ST	P23508	MCC	Q13535	ATR	T496	R501Q	501	Missense	distal	5	no	14.736	14.727	EPSD	ICGC;COSMIC	10.658	Down-regulation
Atypical_PIKK_ATR_ATR_ST	P23508	MCC	Q13535	ATR	T496	S490L	490	Missense	distal	-6	no	14.736	14.846	EPSD	ICGC;COSMIC	10.658	Up-regulation
Atypical_PIKK_ATR_ATR_ST	P23508	MCC	Q13535	ATR	T496	H503N	503	Missense	distal	7	no	14.736	14.865	EPSD	ICGC;COSMIC	10.658	Up-regulation
Atypical_PIKK_ATR_ATR_ST	P23508	MCC	Q13535	ATR	S702	P703Q	703	Missense	proximal	1	no	14.939	19.807	EPSD	ICGC;COSMIC	10.658	Up-regulation
Atypical_PIKK_ATR_ATR_ST	P23508	MCC	Q13535	ATR	S770	D764H	764	Missense	distal	-6	no	10.964	10.989	EPSD	ICGC;COSMIC	10.658	Up-regulation
Atypical_PIKK_ATR_ATR_ST	P23508	MCC	Q13535	ATR	S770	E777Q	777	Missense	distal	7	no	10.964	11.024	EPSD	ICGC;COSMIC	10.658	Up-regulation
Atypical_PIKK_ATR_ATR_ST	P23508	MCC	Q13535	ATR	S792	K789N	789	Missense	distal	-3	no	12.484	13.644	EPSD	ICGC;COSMIC	10.658	Up-regulation
Atypical_PIKK_ATR_ATR_ST	O14757	CHEK1	Q13535	ATR	S317	R322L	322	Missense	distal	5	no	17.676	17.672	EPSD;PhosphoSitePlus	ICGC	10.658	Down-regulation
Atypical_PIKK_ATR_ATR_ST	O14757	CHEK1	Q13535	ATR	S345	L338S	338	Missense	distal	-7	no	17.127	17.292	EPSD;PhosphoSitePlus	ICGC;COSMIC	10.658	Up-regulation
Atypical_PIKK_ATR_ATR_ST	O14757	CHEK1	Q13535	ATR	S357	G364V	364	Missense	distal	7	no	14.888	15.133	EPSD	ICGC;COSMIC	10.658	Up-regulation
Atypical_PIKK_ATR_ATR_ST	O14757	CHEK1	Q13535	ATR	S366	G364V	364	Missense	proximal	-2	no	15.551	15.494	EPSD	ICGC;COSMIC	10.658	Down-regulation
Atypical_PIKK_ATR_ATR_ST	O14757	CHEK1	Q13535	ATR	S468	I471V	471	Missense	distal	3	no	10.983	11.073	EPSD	ICGC	10.658	Up-regulation
Atypical_PIKK_ATR_ATR_ST	O14757	CHEK1	Q13535	ATR	S468	S468C	468	Missense	central	0	yes	10.983	0.000	EPSD	ICGC;COSMIC	10.658	Loss
Atypical_PIKK_ATR_ATR_ST	Q12888	TP53BP1	Q13535	ATR	S6	T4A	4	Missense	proximal	-2	no	12.313	12.786	EPSD	ICGC	10.658	Up-regulation
Atypical_PIKK_ATR_ATR_ST	Q12888	TP53BP1	Q13535	ATR	S6	G5E	5	Missense	proximal	-1	no	12.313	12.361	EPSD	ICGC;COSMIC	10.658	Up-regulation
Atypical_PIKK_ATR_ATR_ST	Q12888	TP53BP1	Q13535	ATR	S29	D24V	24	Missense	distal	-5	no	12.223	12.154	EPSD	ICGC;COSMIC	10.658	Down-regulation
Atypical_PIKK_ATR_ATR_ST	Q12888	TP53BP1	Q13535	ATR	S105	I104F	104	Missense	proximal	-1	no	12.551	12.281	EPSD	ICGC;COSMIC	10.658	Down-regulation
Atypical_PIKK_ATR_ATR_ST	Q12888	TP53BP1	Q13535	ATR	S105	Q106K	106	Missense	proximal	1	no	12.551	1.585	EPSD	ICGC;COSMIC	10.658	Loss
Atypical_PIKK_ATR_ATR_ST	Q12888	TP53BP1	Q13535	ATR	S105	I104M	104	Missense	proximal	-1	no	12.551	12.449	EPSD	ICGC;COSMIC	10.658	Down-regulation
Atypical_PIKK_ATR_ATR_ST	Q12888	TP53BP1	Q13535	ATR	S105	Q106E	106	Missense	proximal	1	no	12.551	6.630	EPSD	ICGC;COSMIC	10.658	Loss
Atypical_PIKK_ATR_ATR_ST	Q12888	TP53BP1	Q13535	ATR	S166	L173M	173	Missense	distal	7	no	13.009	12.842	EPSD;PhosphoSitePlus	ICGC	10.658	Down-regulation
Atypical_PIKK_ATR_ATR_ST	Q12888	TP53BP1	Q13535	ATR	S176	E183K	183	Missense	distal	7	no	14.731	14.880	EPSD;PhosphoSitePlus	ICGC	10.658	Up-regulation
Atypical_PIKK_ATR_ATR_ST	Q12888	TP53BP1	Q13535	ATR	S176	L173M	173	Missense	distal	-3	no	14.731	14.175	EPSD;PhosphoSitePlus	ICGC	10.658	Down-regulation
Atypical_PIKK_ATR_ATR_ST	Q12888	TP53BP1	Q13535	ATR	S176	Q179H	179	Missense	distal	3	no	14.731	15.133	EPSD;PhosphoSitePlus	ICGC	10.658	Up-regulation
Atypical_PIKK_ATR_ATR_ST	Q12888	TP53BP1	Q13535	ATR	S178	E183K	183	Missense	distal	5	no	15.473	15.482	EPSD;PhosphoSitePlus	ICGC	10.658	Up-regulation
Atypical_PIKK_ATR_ATR_ST	Q12888	TP53BP1	Q13535	ATR	S178	L173M	173	Missense	distal	-5	no	15.473	15.188	EPSD;PhosphoSitePlus	ICGC	10.658	Down-regulation
Atypical_PIKK_ATR_ATR_ST	Q12888	TP53BP1	Q13535	ATR	S178	Q179H	179	Missense	proximal	1	no	15.473	-2.045	EPSD;PhosphoSitePlus	ICGC	10.658	Loss
Atypical_PIKK_ATR_ATR_ST	Q12888	TP53BP1	Q13535	ATR	T302	E296D	296	Missense	distal	-6	no	16.265	16.273	PhosphoSitePlus;EPSD	ICGC;COSMIC	10.658	Up-regulation
Atypical_PIKK_ATR_ATR_ST	Q12888	TP53BP1	Q13535	ATR	T302	Q309K	309	Missense	distal	7	no	16.265	16.354	PhosphoSitePlus;EPSD	ICGC	10.658	Up-regulation
Atypical_PIKK_ATR_ATR_ST	Q12888	TP53BP1	Q13535	ATR	T302	D305Y	305	Missense	distal	3	no	16.265	15.773	PhosphoSitePlus;EPSD	ICGC	10.658	Down-regulation
Atypical_PIKK_ATR_ATR_ST	Q12888	TP53BP1	Q13535	ATR	S398	T394S	394	Missense	distal	-4	no	11.585	11.671	EPSD	ICGC;COSMIC	10.658	Up-regulation
Atypical_PIKK_ATR_ATR_ST	Q12888	TP53BP1	Q13535	ATR	S452	S452C	452	Missense	central	0	yes	11.136	0.000	EPSD;PhosphoSitePlus	ICGC;COSMIC	10.658	Loss
Atypical_PIKK_ATR_ATR_ST	Q12888	TP53BP1	Q13535	ATR	S500	K498N	498	Missense	proximal	-2	no	10.351	10.804	EPSD	ICGC;COSMIC	10.658	Gain
Atypical_PIKK_ATR_ATR_ST	Q12888	TP53BP1	Q13535	ATR	S523	P526Q	526	Missense	distal	3	no	14.431	14.064	EPSD	ICGC;COSMIC	10.658	Down-regulation
Atypical_PIKK_ATR_ATR_ST	Q12888	TP53BP1	Q13535	ATR	S523	M528I	528	Missense	distal	5	no	14.431	14.435	EPSD	ICGC;COSMIC	10.658	Up-regulation
Atypical_PIKK_ATR_ATR_ST	Q12888	TP53BP1	Q13535	ATR	S523	S523N	523	Missense	central	0	yes	14.431	0.000	EPSD	ICGC	10.658	Loss
Atypical_PIKK_ATR_ATR_ST	Q12888	TP53BP1	Q13535	ATR	S523	K527N	527	Missense	distal	4	no	14.431	15.200	EPSD	ICGC;COSMIC	10.658	Up-regulation
Atypical_PIKK_ATR_ATR_ST	Q12888	TP53BP1	Q13535	ATR	S525	P526Q	526	Missense	proximal	1	no	10.956	15.824	EPSD	ICGC;COSMIC	10.658	Up-regulation
Atypical_PIKK_ATR_ATR_ST	Q12888	TP53BP1	Q13535	ATR	S525	M528I	528	Missense	distal	3	no	10.956	11.657	EPSD	ICGC;COSMIC	10.658	Up-regulation
Atypical_PIKK_ATR_ATR_ST	Q12888	TP53BP1	Q13535	ATR	S525	S523N	523	Missense	proximal	-2	no	10.956	11.805	EPSD	ICGC	10.658	Up-regulation
Atypical_PIKK_ATR_ATR_ST	Q12888	TP53BP1	Q13535	ATR	S525	K527N	527	Missense	proximal	2	no	10.956	11.150	EPSD	ICGC;COSMIC	10.658	Up-regulation
Atypical_PIKK_ATR_ATR_ST	Q12888	TP53BP1	Q13535	ATR	T543	P550H	550	Missense	distal	7	no	14.275	14.365	EPSD	ICGC;COSMIC	10.658	Up-regulation
Atypical_PIKK_ATR_ATR_ST	Q12888	TP53BP1	Q13535	ATR	T543	N542I	542	Missense	proximal	-1	no	14.275	14.070	EPSD	ICGC;COSMIC	10.658	Down-regulation
Atypical_PIKK_ATR_ATR_ST	Q12888	TP53BP1	Q13535	ATR	T543	E546D	546	Missense	distal	3	no	14.275	14.165	EPSD	ICGC;COSMIC	10.658	Down-regulation
Atypical_PIKK_ATR_ATR_ST	Q12888	TP53BP1	Q13535	ATR	T543	D539E	539	Missense	distal	-4	no	14.275	14.457	EPSD	ICGC;COSMIC	10.658	Up-regulation
Atypical_PIKK_ATR_ATR_ST	Q12888	TP53BP1	Q13535	ATR	T543	P550S	550	Missense	distal	7	no	14.275	14.112	EPSD	ICGC;COSMIC	10.658	Down-regulation
Atypical_PIKK_ATR_ATR_ST	Q12888	TP53BP1	Q13535	ATR	T543	E549K	549	Missense	distal	6	no	14.275	14.075	EPSD	ICGC;COSMIC	10.658	Down-regulation
Atypical_PIKK_ATR_ATR_ST	Q12888	TP53BP1	Q13535	ATR	T543	E541K	541	Missense	proximal	-2	no	14.275	14.375	EPSD	ICGC	10.658	Up-regulation
Atypical_PIKK_ATR_ATR_ST	Q12888	TP53BP1	Q13535	ATR	S580	Q573H	573	Missense	distal	-7	no	17.460	17.480	EPSD	ICGC;COSMIC	10.658	Up-regulation
Atypical_PIKK_ATR_ATR_ST	Q12888	TP53BP1	Q13535	ATR	S580	G575C	575	Missense	distal	-5	no	17.460	17.633	EPSD	ICGC;COSMIC	10.658	Up-regulation
Atypical_PIKK_ATR_ATR_ST	Q12888	TP53BP1	Q13535	ATR	S580	D583Y	583	Missense	distal	3	no	17.460	16.967	EPSD	ICGC	10.658	Down-regulation
Atypical_PIKK_ATR_ATR_ST	Q12888	TP53BP1	Q13535	ATR	S625	P629L	629	Missense	distal	4	no	13.226	13.376	EPSD	ICGC;COSMIC	10.658	Up-regulation
Atypical_PIKK_ATR_ATR_ST	Q12888	TP53BP1	Q13535	ATR	T633	R634Q	634	Missense	proximal	1	no	6.680	13.675	EPSD	ICGC;COSMIC	10.658	Gain
Atypical_PIKK_ATR_ATR_ST	Q12888	TP53BP1	Q13535	ATR	S674	G676A	676	Missense	proximal	2	no	14.053	13.262	EPSD	ICGC;COSMIC	10.658	Down-regulation
Atypical_PIKK_ATR_ATR_ST	Q12888	TP53BP1	Q13535	ATR	S674	P668S	668	Missense	distal	-6	no	14.053	14.007	EPSD	ICGC;COSMIC	10.658	Down-regulation
Atypical_PIKK_ATR_ATR_ST	Q12888	TP53BP1	Q13535	ATR	S674	I667F	667	Missense	distal	-7	no	14.053	14.062	EPSD	ICGC;COSMIC	10.658	Up-regulation
Atypical_PIKK_ATR_ATR_ST	Q12888	TP53BP1	Q13535	ATR	S674	L679H	679	Missense	distal	5	no	14.053	14.051	EPSD	ICGC;COSMIC	10.658	Down-regulation
Atypical_PIKK_ATR_ATR_ST	Q12888	TP53BP1	Q13535	ATR	S674	L679P	679	Missense	distal	5	no	14.053	14.058	EPSD	ICGC;COSMIC	10.658	Up-regulation
Atypical_PIKK_ATR_ATR_ST	Q12888	TP53BP1	Q13535	ATR	S692	P688S	688	Missense	distal	-4	no	11.137	10.812	EPSD	ICGC;COSMIC	10.658	Down-regulation
Atypical_PIKK_ATR_ATR_ST	Q12888	TP53BP1	Q13535	ATR	S692	P688L	688	Missense	distal	-4	no	11.137	9.938	EPSD	ICGC	10.658	Loss
Atypical_PIKK_ATR_ATR_ST	Q12888	TP53BP1	Q13535	ATR	S692	S686R	686	Missense	distal	-6	no	11.137	11.220	EPSD	ICGC	10.658	Up-regulation
Atypical_PIKK_ATR_ATR_ST	Q12888	TP53BP1	Q13535	ATR	T750	S755I	755	Missense	distal	5	no	12.074	12.086	EPSD	ICGC;COSMIC	10.658	Up-regulation
Atypical_PIKK_ATR_ATR_ST	Q12888	TP53BP1	Q13535	ATR	T750	S755R	755	Missense	distal	5	no	12.074	12.085	EPSD	ICGC	10.658	Up-regulation
Atypical_PIKK_ATR_ATR_ST	Q12888	TP53BP1	Q13535	ATR	T750	S754F	754	Missense	distal	4	no	12.074	12.093	EPSD	ICGC;COSMIC	10.658	Up-regulation
Atypical_PIKK_ATR_ATR_ST	Q12888	TP53BP1	Q13535	ATR	S831	S831L	831	Missense	central	0	yes	14.534	0.000	EPSD;PhosphoSitePlus	ICGC;COSMIC	10.658	Loss
Atypical_PIKK_ATR_ATR_ST	Q12888	TP53BP1	Q13535	ATR	S831	Q832K	832	Missense	proximal	1	no	14.534	3.568	EPSD;PhosphoSitePlus	ICGC	10.658	Loss
Atypical_PIKK_ATR_ATR_ST	Q12888	TP53BP1	Q13535	ATR	S831	S834F	834	Missense	distal	3	no	14.534	13.503	EPSD;PhosphoSitePlus	ICGC;COSMIC	10.658	Down-regulation
Atypical_PIKK_ATR_ATR_ST	Q12888	TP53BP1	Q13535	ATR	T855	P853T	853	Missense	proximal	-2	no	13.387	13.638	EPSD	ICGC	10.658	Up-regulation
Atypical_PIKK_ATR_ATR_ST	Q12888	TP53BP1	Q13535	ATR	T855	T855I	855	Missense	central	0	yes	13.387	0.000	EPSD	ICGC;COSMIC	10.658	Loss
Atypical_PIKK_ATR_ATR_ST	Q12888	TP53BP1	Q13535	ATR	T855	Q854H	854	Missense	proximal	-1	no	13.387	13.351	EPSD	ICGC;COSMIC	10.658	Down-regulation
Atypical_PIKK_ATR_ATR_ST	Q12888	TP53BP1	Q13535	ATR	S892	S888C	888	Missense	distal	-4	no	13.351	12.062	EPSD	ICGC;COSMIC	10.658	Down-regulation
Atypical_PIKK_ATR_ATR_ST	Q12888	TP53BP1	Q13535	ATR	S999	E1000Q	1000	Missense	proximal	1	no	9.879	15.800	EPSD	ICGC;GDSC	10.658	Gain
Atypical_PIKK_ATR_ATR_ST	Q12888	TP53BP1	Q13535	ATR	T1032	I1039M	1039	Missense	distal	7	no	13.199	12.874	EPSD	ICGC;COSMIC	10.658	Down-regulation
Atypical_PIKK_ATR_ATR_ST	Q12888	TP53BP1	Q13535	ATR	T1032	A1027S	1027	Missense	distal	-5	no	13.199	13.104	EPSD	ICGC;COSMIC	10.658	Down-regulation
Atypical_PIKK_ATR_ATR_ST	Q12888	TP53BP1	Q13535	ATR	T1032	S1037I	1037	Missense	distal	5	no	13.199	13.211	EPSD	ICGC;COSMIC	10.658	Up-regulation
Atypical_PIKK_ATR_ATR_ST	Q12888	TP53BP1	Q13535	ATR	S1068	E1075Q	1075	Missense	distal	7	no	15.675	15.735	EPSD	ICGC;COSMIC	10.658	Up-regulation
Atypical_PIKK_ATR_ATR_ST	Q12888	TP53BP1	Q13535	ATR	S1068	E1073D	1073	Missense	distal	5	no	15.675	15.690	EPSD	ICGC;COSMIC	10.658	Up-regulation
Atypical_PIKK_ATR_ATR_ST	Q12888	TP53BP1	Q13535	ATR	S1068	P1066Q	1066	Missense	proximal	-2	no	15.675	15.954	EPSD	ICGC;COSMIC	10.658	Up-regulation
Atypical_PIKK_ATR_ATR_ST	Q12888	TP53BP1	Q13535	ATR	S1086	I1093F	1093	Missense	distal	7	no	11.939	11.681	EPSD	ICGC;COSMIC	10.658	Down-regulation
Atypical_PIKK_ATR_ATR_ST	Q12888	TP53BP1	Q13535	ATR	S1086	D1080E	1080	Missense	distal	-6	no	11.939	11.931	EPSD	ICGC	10.658	Down-regulation
Atypical_PIKK_ATR_ATR_ST	Q12888	TP53BP1	Q13535	ATR	S1086	Q1085K	1085	Missense	proximal	-1	no	11.939	11.775	EPSD	ICGC	10.658	Down-regulation
Atypical_PIKK_ATR_ATR_ST	Q12888	TP53BP1	Q13535	ATR	S1086	G1079C	1079	Missense	distal	-7	no	11.939	11.761	EPSD	ICGC;COSMIC	10.658	Down-regulation
Atypical_PIKK_ATR_ATR_ST	Q12888	TP53BP1	Q13535	ATR	S1104	I1109T	1109	Missense	distal	5	no	15.441	15.437	EPSD	ICGC;COSMIC	10.658	Down-regulation
Atypical_PIKK_ATR_ATR_ST	Q12888	TP53BP1	Q13535	ATR	S1104	S1101Y	1101	Missense	distal	-3	no	15.441	16.277	EPSD	ICGC;COSMIC	10.658	Up-regulation
Atypical_PIKK_ATR_ATR_ST	Q12888	TP53BP1	Q13535	ATR	S1148	E1145K	1145	Missense	distal	-3	no	14.705	14.430	EPSD	ICGC;COSMIC	10.658	Down-regulation
Atypical_PIKK_ATR_ATR_ST	Q12888	TP53BP1	Q13535	ATR	S1148	G1153V	1153	Missense	distal	5	no	14.705	14.701	EPSD	ICGC;COSMIC	10.658	Down-regulation
Atypical_PIKK_ATR_ATR_ST	Q12888	TP53BP1	Q13535	ATR	T1156	L1161F	1161	Missense	distal	5	no	11.050	11.055	EPSD	ICGC;COSMIC	10.658	Up-regulation
Atypical_PIKK_ATR_ATR_ST	Q12888	TP53BP1	Q13535	ATR	T1156	M1157R	1157	Missense	proximal	1	no	11.050	8.140	EPSD	ICGC;COSMIC	10.658	Loss
Atypical_PIKK_ATR_ATR_ST	Q12888	TP53BP1	Q13535	ATR	T1156	G1153V	1153	Missense	distal	-3	no	11.050	11.449	EPSD	ICGC;COSMIC	10.658	Up-regulation
Atypical_PIKK_ATR_ATR_ST	Q12888	TP53BP1	Q13535	ATR	T1171	E1165K	1165	Missense	distal	-6	no	14.432	14.385	EPSD	ICGC;COSMIC	10.658	Down-regulation
Atypical_PIKK_ATR_ATR_ST	Q12888	TP53BP1	Q13535	ATR	T1171	I1174V	1174	Missense	distal	3	no	14.432	14.523	EPSD	ICGC;COSMIC	10.658	Up-regulation
Atypical_PIKK_ATR_ATR_ST	Q12888	TP53BP1	Q13535	ATR	S1290	C1283R	1283	Missense	distal	-7	no	13.072	13.249	EPSD	ICGC;COSMIC	10.658	Up-regulation
Atypical_PIKK_ATR_ATR_ST	Q12888	TP53BP1	Q13535	ATR	S1304	S1306F	1306	Missense	proximal	2	no	12.642	9.954	EPSD	ICGC;COSMIC	10.658	Loss
Atypical_PIKK_ATR_ATR_ST	Q12888	TP53BP1	Q13535	ATR	S1304	S1310P	1310	Missense	distal	6	no	12.642	12.345	EPSD	ICGC;COSMIC	10.658	Down-regulation
Atypical_PIKK_ATR_ATR_ST	Q12888	TP53BP1	Q13535	ATR	S1304	D1301A	1301	Missense	distal	-3	no	12.642	12.689	EPSD	ICGC;COSMIC	10.658	Up-regulation
Atypical_PIKK_ATR_ATR_ST	Q12888	TP53BP1	Q13535	ATR	S1368	T1372M	1372	Missense	distal	4	no	16.115	15.619	EPSD	ICGC;COSMIC	10.658	Down-regulation
Atypical_PIKK_ATR_ATR_ST	Q12888	TP53BP1	Q13535	ATR	S1368	T1370K	1370	Missense	proximal	2	no	16.115	16.625	EPSD	ICGC;COSMIC	10.658	Up-regulation
Atypical_PIKK_ATR_ATR_ST	Q12888	TP53BP1	Q13535	ATR	S1460	G1455D	1455	Missense	distal	-5	no	12.206	12.358	EPSD	ICGC;COSMIC	10.658	Up-regulation
Atypical_PIKK_ATR_ATR_ST	Q12888	TP53BP1	Q13535	ATR	S1460	R1458C	1458	Missense	proximal	-2	no	12.206	12.436	EPSD	ICGC;COSMIC	10.658	Up-regulation
Atypical_PIKK_ATR_ATR_ST	Q12888	TP53BP1	Q13535	ATR	S1460	G1453C	1453	Missense	distal	-7	no	12.206	12.029	EPSD	ICGC;COSMIC	10.658	Down-regulation
Atypical_PIKK_ATR_ATR_ST	Q12888	TP53BP1	Q13535	ATR	S1460	P1466S	1466	Missense	distal	6	no	12.206	12.503	EPSD	ICGC;COSMIC	10.658	Up-regulation
Atypical_PIKK_ATR_ATR_ST	Q12888	TP53BP1	Q13535	ATR	S1460	R1459H	1459	Missense	proximal	-1	no	12.206	12.100	EPSD	ICGC;COSMIC	10.658	Down-regulation
Atypical_PIKK_ATR_ATR_ST	Q12888	TP53BP1	Q13535	ATR	S1462	G1455D	1455	Missense	distal	-7	no	12.642	12.674	EPSD	ICGC;COSMIC	10.658	Up-regulation
Atypical_PIKK_ATR_ATR_ST	Q12888	TP53BP1	Q13535	ATR	S1462	R1458C	1458	Missense	distal	-4	no	12.642	11.651	EPSD	ICGC;COSMIC	10.658	Down-regulation
Atypical_PIKK_ATR_ATR_ST	Q12888	TP53BP1	Q13535	ATR	S1462	P1466S	1466	Missense	distal	4	no	12.642	12.556	EPSD	ICGC;COSMIC	10.658	Down-regulation
Atypical_PIKK_ATR_ATR_ST	Q12888	TP53BP1	Q13535	ATR	S1462	R1459H	1459	Missense	distal	-3	no	12.642	12.274	EPSD	ICGC;COSMIC	10.658	Down-regulation
Atypical_PIKK_ATR_ATR_ST	Q12888	TP53BP1	Q13535	ATR	S1474	G1472V	1472	Missense	proximal	-2	no	11.193	11.136	EPSD	ICGC;COSMIC	10.658	Down-regulation
Atypical_PIKK_ATR_ATR_ST	Q12888	TP53BP1	Q13535	ATR	S1480	G1483V	1483	Missense	distal	3	no	10.336	10.929	EPSD	ICGC	10.658	Gain
Atypical_PIKK_ATR_ATR_ST	Q12888	TP53BP1	Q13535	ATR	S1660	S1665L	1665	Missense	distal	5	no	13.393	13.400	EPSD	ICGC;COSMIC	10.658	Up-regulation
Atypical_PIKK_ATR_ATR_ST	Q12888	TP53BP1	Q13535	ATR	S1660	V1663I	1663	Missense	distal	3	no	13.393	13.302	EPSD	ICGC;COSMIC	10.658	Down-regulation
Atypical_PIKK_ATR_ATR_ST	Q12888	TP53BP1	Q13535	ATR	S1660	P1657L	1657	Missense	distal	-3	no	13.393	13.688	EPSD	ICGC;COSMIC	10.658	Up-regulation
Atypical_PIKK_ATR_ATR_ST	Q12888	TP53BP1	Q13535	ATR	S1660	L1664I	1664	Missense	distal	4	no	13.393	13.839	EPSD	ICGC	10.658	Up-regulation
Atypical_PIKK_ATR_ATR_ST	Q12888	TP53BP1	Q13535	ATR	S1673	E1676K	1676	Missense	distal	3	no	10.630	10.787	EPSD	ICGC;COSMIC	10.658	Gain
Atypical_PIKK_ATR_ATR_ST	Q12888	TP53BP1	Q13535	ATR	S1673	R1677W	1677	Missense	distal	4	no	10.630	10.961	EPSD	ICGC;COSMIC	10.658	Gain
Atypical_PIKK_ATR_ATR_ST	Q12888	TP53BP1	Q13535	ATR	S1678	R1684H	1684	Missense	distal	6	no	10.995	11.070	EPSD	ICGC;COSMIC	10.658	Up-regulation
Atypical_PIKK_ATR_ATR_ST	Q12888	TP53BP1	Q13535	ATR	S1678	E1676K	1676	Missense	proximal	-2	no	10.995	11.095	EPSD	ICGC;COSMIC	10.658	Up-regulation
Atypical_PIKK_ATR_ATR_ST	Q12888	TP53BP1	Q13535	ATR	S1678	R1684C	1684	Missense	distal	6	no	10.995	11.208	EPSD	ICGC;COSMIC	10.658	Up-regulation
Atypical_PIKK_ATR_ATR_ST	Q12888	TP53BP1	Q13535	ATR	S1678	R1677W	1677	Missense	proximal	-1	no	10.995	11.093	EPSD	ICGC;COSMIC	10.658	Up-regulation
Atypical_PIKK_ATR_ATR_ST	Q12888	TP53BP1	Q13535	ATR	S1678	R1677Q	1677	Missense	proximal	-1	no	10.995	10.925	EPSD	ICGC;COSMIC	10.658	Down-regulation
Atypical_PIKK_ATR_ATR_ST	Q12888	TP53BP1	Q13535	ATR	S1778	G1783A	1783	Missense	distal	5	no	13.247	13.253	EPSD	ICGC;COSMIC	10.658	Up-regulation
Atypical_PIKK_ATR_ATR_ST	Q12888	TP53BP1	Q13535	ATR	S1778	R1781Q	1781	Missense	distal	3	no	13.247	13.252	EPSD	ICGC;COSMIC	10.658	Up-regulation
Atypical_PIKK_ATR_ATR_ST	Q12888	TP53BP1	Q13535	ATR	S1778	F1771L	1771	Missense	distal	-7	no	13.247	13.189	EPSD	ICGC;COSMIC	10.658	Down-regulation
Atypical_PIKK_ATR_ATR_ST	Q12888	TP53BP1	Q13535	ATR	S1778	F1771Y	1771	Missense	distal	-7	no	13.247	13.181	EPSD	ICGC;COSMIC	10.658	Down-regulation
Atypical_PIKK_ATR_ATR_ST	Q96RL1	UIMC1	Q13535	ATR	S140	P133S	133	Missense	distal	-7	no	13.466	13.438	EPSD	ICGC	10.658	Down-regulation
Atypical_PIKK_ATR_ATR_ST	Q96RL1	UIMC1	Q13535	ATR	S171	H169N	169	Missense	proximal	-2	no	12.550	13.434	EPSD	ICGC	10.658	Up-regulation
Atypical_PIKK_ATR_ATR_ST	Q96RL1	UIMC1	Q13535	ATR	T448	Q449K	449	Missense	proximal	1	no	12.626	1.659	EPSD	ICGC	10.658	Loss
Atypical_PIKK_ATR_ATR_ST	Q96RL1	UIMC1	Q13535	ATR	T448	S452F	452	Missense	distal	4	no	12.626	12.644	EPSD	ICGC;GDSC;CCLE	10.658	Up-regulation
Atypical_PIKK_ATR_ATR_ST	Q96RL1	UIMC1	Q13535	ATR	T448	T448N	448	Missense	central	0	yes	12.626	0.000	EPSD	ICGC	10.658	Loss
Atypical_PIKK_ATR_ATR_ST	Q96RL1	UIMC1	Q13535	ATR	S451	T448N	448	Missense	distal	-3	no	10.503	11.310	EPSD	ICGC	10.658	Gain
Atypical_PIKK_ATR_ATR_ST	Q96RL1	UIMC1	Q13535	ATR	S677	R672C	672	Missense	distal	-5	no	12.139	12.146	EPSD	ICGC	10.658	Up-regulation
Atypical_PIKK_ATR_ATR_ST	P39880	CUX1	Q13535	ATR	S322	A321T	321	Missense	proximal	-1	no	14.706	14.476	EPSD	ICGC;COSMIC	10.658	Down-regulation
Atypical_PIKK_ATR_ATR_ST	P39880	CUX1	Q13535	ATR	S369	D376Y	376	Missense	distal	7	no	10.632	10.660	EPSD	ICGC;COSMIC	10.658	Gain
Atypical_PIKK_ATR_ATR_ST	P39880	CUX1	Q13535	ATR	T374	P368L	368	Missense	distal	-6	no	15.839	15.903	EPSD	ICGC;COSMIC	10.658	Up-regulation
Atypical_PIKK_ATR_ATR_ST	P39880	CUX1	Q13535	ATR	T374	D376Y	376	Missense	proximal	2	no	15.839	14.167	EPSD	ICGC;COSMIC	10.658	Down-regulation
Atypical_PIKK_ATR_ATR_ST	P39880	CUX1	Q13535	ATR	T374	A377V	377	Missense	distal	3	no	15.839	16.599	EPSD	ICGC;COSMIC	10.658	Up-regulation
Atypical_PIKK_ATR_ATR_ST	P39880	CUX1	Q13535	ATR	S391	A397T	397	Missense	distal	6	no	10.385	10.664	EPSD	ICGC;COSMIC	10.658	Gain
Atypical_PIKK_ATR_ATR_ST	P39880	CUX1	Q13535	ATR	S404	R400K	400	Missense	distal	-4	no	10.157	11.059	EPSD	ICGC;COSMIC	10.658	Gain
Atypical_PIKK_ATR_ATR_ST	P39880	CUX1	Q13535	ATR	S432	P427L	427	Missense	distal	-5	no	12.920	13.073	EPSD	ICGC;COSMIC	10.658	Up-regulation
Atypical_PIKK_ATR_ATR_ST	P39880	CUX1	Q13535	ATR	S432	A428P	428	Missense	distal	-4	no	12.920	12.724	EPSD	ICGC;COSMIC	10.658	Down-regulation
Atypical_PIKK_ATR_ATR_ST	P39880	CUX1	Q13535	ATR	S432	L434M	434	Missense	proximal	2	no	12.920	14.291	EPSD	ICGC;COSMIC	10.658	Up-regulation
Atypical_PIKK_ATR_ATR_ST	P39880	CUX1	Q13535	ATR	S432	P429L	429	Missense	distal	-3	no	12.920	13.214	EPSD	ICGC;COSMIC	10.658	Up-regulation
Atypical_PIKK_ATR_ATR_ST	P39880	CUX1	Q13535	ATR	S868	Q869K	869	Missense	proximal	1	no	11.489	0.523	EPSD	ICGC;COSMIC	10.658	Loss
Atypical_PIKK_ATR_ATR_ST	P39880	CUX1	Q13535	ATR	S1059	P1057S	1057	Missense	proximal	-2	no	11.727	11.676	EPSD	ICGC	10.658	Down-regulation
Atypical_PIKK_ATR_ATR_ST	P39880	CUX1	Q13535	ATR	S1059	P1055S	1055	Missense	distal	-4	no	11.727	11.402	EPSD	ICGC;COSMIC	10.658	Down-regulation
Atypical_PIKK_ATR_ATR_ST	P39880	CUX1	Q13535	ATR	S1059	P1057L	1057	Missense	proximal	-2	no	11.727	12.378	EPSD	ICGC;COSMIC	10.658	Up-regulation
Atypical_PIKK_ATR_ATR_ST	P39880	CUX1	Q13535	ATR	S1063	P1057S	1057	Missense	distal	-6	no	11.867	11.822	EPSD	ICGC	10.658	Down-regulation
Atypical_PIKK_ATR_ATR_ST	P39880	CUX1	Q13535	ATR	S1063	P1057L	1057	Missense	distal	-6	no	11.867	11.931	EPSD	ICGC;COSMIC	10.658	Up-regulation
Atypical_PIKK_ATR_ATR_ST	P39880	CUX1	Q13535	ATR	S1100	S1093I	1093	Missense	distal	-7	no	13.302	13.185	EPSD	ICGC	10.658	Down-regulation
Atypical_PIKK_ATR_ATR_ST	P39880	CUX1	Q13535	ATR	S1100	P1102R	1102	Missense	proximal	2	no	13.302	12.713	EPSD	ICGC;COSMIC	10.658	Down-regulation
Atypical_PIKK_ATR_ATR_ST	Q01094	E2F1	Q13535	ATR	S313	P308T	308	Missense	distal	-5	no	14.237	14.220	EPSD	ICGC	10.658	Down-regulation
Atypical_PIKK_ATR_ATR_ST	Q01094	E2F1	Q13535	ATR	S313	S318A	318	Missense	distal	5	no	14.237	14.249	EPSD	ICGC	10.658	Up-regulation
Atypical_PIKK_ATR_ATR_ST	Q01094	E2F1	Q13535	ATR	S364	V369M	369	Missense	distal	5	no	10.805	10.812	EPSD	ICGC	10.658	Up-regulation
Atypical_PIKK_ATR_ATR_ST	Q01094	E2F1	Q13535	ATR	S364	R361Q	361	Missense	distal	-3	no	10.805	10.621	EPSD	ICGC	10.658	Loss
Atypical_PIKK_ATR_ATR_ST	Q01094	E2F1	Q13535	ATR	S364	S360F	360	Missense	distal	-4	no	10.805	10.522	EPSD	ICGC	10.658	Loss
Atypical_PIKK_ATR_ATR_ST	P04637	TP53	Q13535	ATR	S6	E11K	11	Missense	distal	5	no	10.901	10.910	EPSD	ICGC;COSMIC	10.658	Up-regulation
Atypical_PIKK_ATR_ATR_ST	P04637	TP53	Q13535	ATR	S15	E11K	11	Missense	distal	-4	no	19.335	18.925	EPSD;PhosphoSitePlus	ICGC;COSMIC	10.658	Down-regulation
Atypical_PIKK_ATR_ATR_ST	P04637	TP53	Q13535	ATR	S37	P34L	34	Missense	distal	-3	no	17.659	17.954	PhosphoSitePlus;EPSD	ICGC;COSMIC	10.658	Up-regulation
Atypical_PIKK_ATR_ATR_ST	P04637	TP53	Q13535	ATR	S37	S33F	33	Missense	distal	-4	no	17.659	17.376	PhosphoSitePlus;EPSD	ICGC;COSMIC	10.658	Down-regulation
Atypical_PIKK_ATR_ATR_ST	P04637	TP53	Q13535	ATR	S37	N30I	30	Missense	distal	-7	no	17.659	17.676	PhosphoSitePlus;EPSD	ICGC	10.658	Up-regulation
Atypical_PIKK_ATR_ATR_ST	P04637	TP53	Q13535	ATR	S46	D48G	48	Missense	proximal	2	no	9.320	10.866	EPSD	ICGC;COSMIC	10.658	Gain
Atypical_PIKK_ATR_ATR_ST	P04637	TP53	Q13535	ATR	S99	Q100K	100	Missense	proximal	1	no	13.266	2.300	EPSD	ICGC;COSMIC	10.658	Loss
Atypical_PIKK_ATR_ATR_ST	P04637	TP53	Q13535	ATR	S99	P92T	92	Missense	distal	-7	no	13.266	13.180	EPSD	ICGC;COSMIC	10.658	Down-regulation
Atypical_PIKK_ATR_ATR_ST	P04637	TP53	Q13535	ATR	S99	P92H	92	Missense	distal	-7	no	13.266	13.243	EPSD	ICGC;COSMIC	10.658	Down-regulation
Atypical_PIKK_ATR_ATR_ST	P04637	TP53	Q13535	ATR	S99	G105A	105	Missense	distal	6	no	13.266	13.182	EPSD	ICGC;COSMIC	10.658	Down-regulation
Atypical_PIKK_ATR_ATR_ST	P04637	TP53	Q13535	ATR	S106	Q100K	100	Missense	distal	-6	no	11.409	11.344	EPSD	ICGC;COSMIC	10.658	Down-regulation
Atypical_PIKK_ATR_ATR_ST	P04637	TP53	Q13535	ATR	S106	F113I	113	Missense	distal	7	no	11.409	11.667	EPSD	ICGC;COSMIC	10.658	Up-regulation
Atypical_PIKK_ATR_ATR_ST	P04637	TP53	Q13535	ATR	S106	G105A	105	Missense	proximal	-1	no	11.409	11.592	EPSD	ICGC;COSMIC	10.658	Up-regulation
Atypical_PIKK_ATR_ATR_ST	P04637	TP53	Q13535	ATR	T211	H214D	214	Missense	distal	3	no	10.866	10.469	EPSD	ICGC;COSMIC	10.658	Loss
Atypical_PIKK_ATR_ATR_ST	P04637	TP53	Q13535	ATR	T211	H214Y	214	Missense	distal	3	no	10.866	9.976	EPSD	ICGC;COSMIC	10.658	Loss
Atypical_PIKK_ATR_ATR_ST	P04637	TP53	Q13535	ATR	T211	T211P	211	Missense	central	0	yes	10.866	0.000	EPSD	ICGC;COSMIC	10.658	Loss
Atypical_PIKK_ATR_ATR_ST	P04637	TP53	Q13535	ATR	T211	F212V	212	Missense	proximal	1	no	10.866	-2.145	EPSD	ICGC;COSMIC	10.658	Loss
Atypical_PIKK_ATR_ATR_ST	P04637	TP53	Q13535	ATR	T211	D208V	208	Missense	distal	-3	no	10.866	10.513	EPSD	ICGC;COSMIC	10.658	Loss
Atypical_PIKK_ATR_ATR_ST	P04637	TP53	Q13535	ATR	T211	V217G	217	Missense	distal	6	no	10.866	10.736	EPSD	ICGC;COSMIC;CCLE	10.658	Down-regulation
Atypical_PIKK_ATR_ATR_ST	P04637	TP53	Q13535	ATR	T211	S215T	215	Missense	distal	4	no	10.866	10.917	EPSD	ICGC;COSMIC	10.658	Up-regulation
Atypical_PIKK_ATR_ATR_ST	Q00987	MDM2	Q13535	ATR	S17	G12R	12	Missense	distal	-5	no	14.492	14.658	EPSD	ICGC;COSMIC	10.658	Up-regulation
Atypical_PIKK_ATR_ATR_ST	Q00987	MDM2	Q13535	ATR	S17	D11Y	11	Missense	distal	-6	no	14.492	14.602	EPSD	ICGC	10.658	Up-regulation
Atypical_PIKK_ATR_ATR_ST	Q00987	MDM2	Q13535	ATR	S17	T10A	10	Missense	distal	-7	no	14.492	14.516	EPSD	ICGC;COSMIC	10.658	Up-regulation
Atypical_PIKK_ATR_ATR_ST	Q00987	MDM2	Q13535	ATR	S260	E267K	267	Missense	distal	7	no	11.590	11.739	EPSD	ICGC;COSMIC	10.658	Up-regulation
Atypical_PIKK_ATR_ATR_ST	Q00987	MDM2	Q13535	ATR	S342	I341V	341	Missense	proximal	-1	no	10.821	10.569	EPSD	ICGC;COSMIC	10.658	Loss
Atypical_PIKK_ATR_ATR_ST	Q00987	MDM2	Q13535	ATR	S386	E390Q	390	Missense	distal	4	no	15.080	15.208	EPSD	ICGC;COSMIC	10.658	Up-regulation
Atypical_PIKK_ATR_ATR_ST	Q00987	MDM2	Q13535	ATR	S388	E390Q	390	Missense	proximal	2	no	15.320	14.067	EPSD	ICGC;COSMIC	10.658	Down-regulation
Atypical_PIKK_ATR_ATR_ST	Q00987	MDM2	Q13535	ATR	S395	S400C	400	Missense	distal	5	no	15.232	15.258	EPSD	ICGC;COSMIC	10.658	Up-regulation
Atypical_PIKK_ATR_ATR_ST	Q00987	MDM2	Q13535	ATR	S395	E390Q	390	Missense	distal	-5	no	15.232	15.405	EPSD	ICGC;COSMIC	10.658	Up-regulation
Atypical_PIKK_ATR_ATR_ST	Q00987	MDM2	Q13535	ATR	S407	S400C	400	Missense	distal	-7	no	15.477	15.253	PhosphoSitePlus	ICGC;COSMIC	10.658	Down-regulation
Atypical_PIKK_ATR_ATR_ST	Q00987	MDM2	Q13535	ATR	T419	V426F	426	Missense	distal	7	no	13.417	13.268	EPSD	ICGC	10.658	Down-regulation
Atypical_PIKK_ATR_ATR_ST	Q96SD1	DCLRE1C	Q13535	ATR	S3	F4L	4	Missense	proximal	1	no	9.529	10.779	EPSD	ICGC	10.658	Gain
Atypical_PIKK_ATR_ATR_ST	Q96SD1	DCLRE1C	Q13535	ATR	T500	L504V	504	Missense	distal	4	no	12.716	12.641	EPSD	ICGC;COSMIC	10.658	Down-regulation
Atypical_PIKK_ATR_ATR_ST	Q96SD1	DCLRE1C	Q13535	ATR	S538	E545Q	545	Missense	distal	7	no	11.890	11.950	EPSD	ICGC;COSMIC	10.658	Up-regulation
Atypical_PIKK_ATR_ATR_ST	Q96SD1	DCLRE1C	Q13535	ATR	S548	E545Q	545	Missense	distal	-3	no	14.606	14.759	EPSD	ICGC;COSMIC	10.658	Up-regulation
Atypical_PIKK_ATR_ATR_ST	Q8WVB6	CHTF18	Q13535	ATR	S405	S401P	401	Missense	distal	-4	no	11.745	12.070	EPSD	ICGC;COSMIC	10.658	Up-regulation
Atypical_PIKK_ATR_ATR_ST	P23025	XPA	Q13535	ATR	S173	S173L	173	Missense	central	0	yes	16.194	0.000	EPSD;PhosphoSitePlus	ICGC;COSMIC	10.658	Loss
Atypical_PIKK_ATR_ATR_ST	P23025	XPA	Q13535	ATR	S196	V193I	193	Missense	distal	-3	no	16.492	16.076	PhosphoSitePlus;EPSD	ICGC	10.658	Down-regulation
Atypical_PIKK_ATR_ATR_ST	P23025	XPA	Q13535	ATR	S196	E198D	198	Missense	proximal	2	no	16.492	14.816	PhosphoSitePlus;EPSD	ICGC	10.658	Down-regulation
Atypical_PIKK_ATR_ATR_ST	P08047	SP1	Q13535	ATR	S7	S7P	7	Missense	central	0	yes	11.664	0.000	EPSD	ICGC;COSMIC	10.658	Loss
Atypical_PIKK_ATR_ATR_ST	P08047	SP1	Q13535	ATR	S7	S7Y	7	Missense	central	0	yes	11.664	0.000	EPSD	ICGC;COSMIC	10.658	Loss
Atypical_PIKK_ATR_ATR_ST	P08047	SP1	Q13535	ATR	S7	M11I	11	Missense	distal	4	no	11.664	12.792	EPSD	ICGC	10.658	Up-regulation
Atypical_PIKK_ATR_ATR_ST	P08047	SP1	Q13535	ATR	S7	M8I	8	Missense	proximal	1	no	11.664	8.260	EPSD	ICGC	10.658	Loss
Atypical_PIKK_ATR_ATR_ST	P08047	SP1	Q13535	ATR	S36	S36L	36	Missense	central	0	yes	15.873	0.000	EPSD	ICGC;COSMIC	10.658	Loss
Atypical_PIKK_ATR_ATR_ST	P08047	SP1	Q13535	ATR	S36	F35L	35	Missense	proximal	-1	no	15.873	16.106	EPSD	ICGC;COSMIC	10.658	Up-regulation
Atypical_PIKK_ATR_ATR_ST	P08047	SP1	Q13535	ATR	S56	S56A	56	Missense	central	0	yes	15.878	0.000	EPSD	ICGC;COSMIC	10.658	Loss
Atypical_PIKK_ATR_ATR_ST	P08047	SP1	Q13535	ATR	T98	N105S	105	Missense	distal	7	no	11.907	11.526	EPSD	ICGC;COSMIC	10.658	Down-regulation
Atypical_PIKK_ATR_ATR_ST	P08047	SP1	Q13535	ATR	T98	G103D	103	Missense	distal	5	no	11.907	11.912	EPSD	ICGC;COSMIC	10.658	Up-regulation
Atypical_PIKK_ATR_ATR_ST	P08047	SP1	Q13535	ATR	S101	N105S	105	Missense	distal	4	no	16.948	16.310	PhosphoSitePlus	ICGC;COSMIC	10.658	Down-regulation
Atypical_PIKK_ATR_ATR_ST	P08047	SP1	Q13535	ATR	S101	G103D	103	Missense	proximal	2	no	16.948	15.402	PhosphoSitePlus	ICGC;COSMIC	10.658	Down-regulation
Atypical_PIKK_ATR_ATR_ST	P08047	SP1	Q13535	ATR	S588	P589Q	589	Missense	proximal	1	no	9.560	14.427	EPSD	ICGC;COSMIC	10.658	Gain
Atypical_PIKK_ATR_ATR_ST	P08047	SP1	Q13535	ATR	S732	A738G	738	Missense	distal	6	no	11.680	11.764	EPSD	ICGC;COSMIC	10.658	Up-regulation
Atypical_PIKK_ATR_ATR_ST	P08047	SP1	Q13535	ATR	T739	A738G	738	Missense	proximal	-1	no	10.850	10.666	EPSD	ICGC;COSMIC	10.658	Down-regulation
Atypical_PIKK_ATR_ATR_ST	P38398	BRCA1	Q13535	ATR	S114	D120G	120	Missense	distal	6	no	16.320	16.267	EPSD	ICGC;COSMIC	10.658	Down-regulation
Atypical_PIKK_ATR_ATR_ST	P38398	BRCA1	Q13535	ATR	S114	H117N	117	Missense	distal	3	no	16.320	16.093	EPSD	ICGC;COSMIC	10.658	Down-regulation
Atypical_PIKK_ATR_ATR_ST	P38398	BRCA1	Q13535	ATR	S127	R133H	133	Missense	distal	6	no	10.588	10.663	EPSD	ICGC;COSMIC	10.658	Gain
Atypical_PIKK_ATR_ATR_ST	P38398	BRCA1	Q13535	ATR	T231	D232H	232	Missense	proximal	1	no	11.059	-1.045	EPSD	ICGC	10.658	Loss
Atypical_PIKK_ATR_ATR_ST	P38398	BRCA1	Q13535	ATR	S646	Q640P	640	Missense	distal	-6	no	10.895	10.866	EPSD	ICGC;COSMIC	10.658	Down-regulation
Atypical_PIKK_ATR_ATR_ST	P38398	BRCA1	Q13535	ATR	S1143	T1149K	1149	Missense	distal	6	no	16.363	16.296	EPSD;PhosphoSitePlus	ICGC	10.658	Down-regulation
Atypical_PIKK_ATR_ATR_ST	P38398	BRCA1	Q13535	ATR	S1173	E1167D	1167	Missense	distal	-6	no	10.919	10.927	EPSD	ICGC;COSMIC	10.658	Up-regulation
Atypical_PIKK_ATR_ATR_ST	P38398	BRCA1	Q13535	ATR	S1262	E1257V	1257	Missense	distal	-5	no	10.595	10.778	EPSD	ICGC;COSMIC	10.658	Gain
Atypical_PIKK_ATR_ATR_ST	O43543	XRCC2	Q13535	ATR	S247	Q248E	248	Missense	proximal	1	no	14.696	8.775	PhosphoSitePlus	ICGC	10.658	Loss
Atypical_PIKK_ATR_ATR_ST	O43543	XRCC2	Q13535	ATR	S247	S250R	250	Missense	distal	3	no	14.696	14.260	PhosphoSitePlus	ICGC	10.658	Down-regulation
Atypical_PIKK_ATR_ATR_ST	Q9UBU7	DBF4	Q13535	ATR	S539	G532S	532	Missense	distal	-7	no	16.416	16.463	EPSD;PhosphoSitePlus	ICGC	10.658	Up-regulation
Atypical_PIKK_ATR_ATR_ST	Q9UBU7	DBF4	Q13535	ATR	T638	Y637C	637	Missense	proximal	-1	no	10.923	11.143	EPSD	ICGC;COSMIC	10.658	Up-regulation
Atypical_PIKK_ATR_ATR_ST	Q8IYD8	FANCM	Q13535	ATR	S832	S826Y	826	Missense	distal	-6	no	11.894	12.068	EPSD	ICGC;COSMIC	10.658	Up-regulation
Atypical_PIKK_ATR_ATR_ST	Q8IYD8	FANCM	Q13535	ATR	S1836	S1835F	1835	Missense	proximal	-1	no	11.868	11.870	EPSD	ICGC;COSMIC	10.658	Up-regulation
Atypical_PIKK_ATR_ATR_ST	Q8IYD8	FANCM	Q13535	ATR	S1836	G1842V	1842	Missense	distal	6	no	11.868	11.997	EPSD	ICGC	10.658	Up-regulation
Atypical_PIKK_ATR_ATR_ST	Q8IYD8	FANCM	Q13535	ATR	S1836	V1833L	1833	Missense	distal	-3	no	11.868	11.999	EPSD	ICGC	10.658	Up-regulation
Atypical_PIKK_ATR_ATR_ST	P27707	DCK	Q13535	ATR	S15	E17D	17	Missense	proximal	2	no	11.612	9.936	EPSD	ICGC;COSMIC	10.658	Loss
Atypical_PIKK_ATR_ATR_ST	P27707	DCK	Q13535	ATR	S15	S8R	8	Missense	distal	-7	no	11.612	11.565	EPSD	ICGC;COSMIC	10.658	Down-regulation
Atypical_PIKK_ATR_ATR_ST	P27707	DCK	Q13535	ATR	S15	R20L	20	Missense	distal	5	no	11.612	11.608	EPSD	ICGC	10.658	Down-regulation
Atypical_PIKK_ATR_ATR_ST	P27707	DCK	Q13535	ATR	S15	R20H	20	Missense	distal	5	no	11.612	11.606	EPSD	ICGC	10.658	Down-regulation
Atypical_PIKK_ATR_ATR_ST	P27707	DCK	Q13535	ATR	T64	R57I	57	Missense	distal	-7	no	13.776	13.706	EPSD	ICGC	10.658	Down-regulation
Atypical_PIKK_ATR_ATR_ST	P27707	DCK	Q13535	ATR	T64	C59F	59	Missense	distal	-5	no	13.776	13.813	EPSD	ICGC	10.658	Up-regulation
Atypical_PIKK_ATR_ATR_ST	P27707	DCK	Q13535	ATR	T64	S63T	63	Missense	proximal	-1	no	13.776	13.822	EPSD	ICGC;COSMIC	10.658	Up-regulation
Atypical_PIKK_ATR_ATR_ST	P27707	DCK	Q13535	ATR	S74	T72A	72	Missense	proximal	-2	no	15.619	16.093	PhosphoSitePlus	ICGC;COSMIC	10.658	Up-regulation
Atypical_PIKK_ATR_ATR_ST	P27707	DCK	Q13535	ATR	S74	T72K	72	Missense	proximal	-2	no	15.619	15.713	PhosphoSitePlus	ICGC;COSMIC	10.658	Up-regulation
Atypical_PIKK_ATR_ATR_ST	Q9BXW9	FANCD2	Q13535	ATR	S126	M127L	127	Missense	proximal	1	no	10.992	9.644	EPSD	ICGC	10.658	Loss
Atypical_PIKK_ATR_ATR_ST	Q9BXW9	FANCD2	Q13535	ATR	S126	S126I	126	Missense	central	0	yes	10.992	0.000	EPSD	ICGC;COSMIC	10.658	Loss
Atypical_PIKK_ATR_ATR_ST	Q9BXW9	FANCD2	Q13535	ATR	S134	L139F	139	Missense	distal	5	no	11.810	11.816	EPSD	ICGC	10.658	Up-regulation
Atypical_PIKK_ATR_ATR_ST	Q9BXW9	FANCD2	Q13535	ATR	S134	M127L	127	Missense	distal	-7	no	11.810	11.657	EPSD	ICGC	10.658	Down-regulation
Atypical_PIKK_ATR_ATR_ST	Q9BXW9	FANCD2	Q13535	ATR	S178	I176V	176	Missense	proximal	-2	no	11.877	11.636	EPSD	ICGC;COSMIC	10.658	Down-regulation
Atypical_PIKK_ATR_ATR_ST	Q9BXW9	FANCD2	Q13535	ATR	S178	Q179K	179	Missense	proximal	1	no	11.877	0.911	EPSD	ICGC;COSMIC	10.658	Loss
Atypical_PIKK_ATR_ATR_ST	Q9BXW9	FANCD2	Q13535	ATR	S319	A318G	318	Missense	proximal	-1	no	15.682	15.499	EPSD	ICGC;COSMIC	10.658	Down-regulation
Atypical_PIKK_ATR_ATR_ST	Q9BXW9	FANCD2	Q13535	ATR	S319	R315L	315	Missense	distal	-4	no	15.682	15.106	EPSD	ICGC;COSMIC	10.658	Down-regulation
Atypical_PIKK_ATR_ATR_ST	Q9BXW9	FANCD2	Q13535	ATR	S592	S590R	590	Missense	proximal	-2	no	10.511	10.921	EPSD	ICGC;COSMIC	10.658	Gain
Atypical_PIKK_ATR_ATR_ST	Q9BXW9	FANCD2	Q13535	ATR	T596	S590R	590	Missense	distal	-6	no	14.160	14.242	EPSD;PhosphoSitePlus	ICGC;COSMIC	10.658	Up-regulation
Atypical_PIKK_ATR_ATR_ST	Q9BXW9	FANCD2	Q13535	ATR	T691	G685R	685	Missense	distal	-6	no	15.569	15.621	EPSD;PhosphoSitePlus	ICGC;COSMIC	10.658	Up-regulation
Atypical_PIKK_ATR_ATR_ST	Q9BXW9	FANCD2	Q13535	ATR	S717	Q718E	718	Missense	proximal	1	no	17.875	11.955	PhosphoSitePlus;EPSD	ICGC	10.658	Down-regulation
Atypical_PIKK_ATR_ATR_ST	Q9BXW9	FANCD2	Q13535	ATR	S717	G721V	721	Missense	distal	4	no	17.875	17.269	PhosphoSitePlus;EPSD	ICGC	10.658	Down-regulation
Atypical_PIKK_ATR_ATR_ST	Q9BXW9	FANCD2	Q13535	ATR	S717	D711E	711	Missense	distal	-6	no	17.875	17.868	PhosphoSitePlus;EPSD	ICGC;COSMIC	10.658	Down-regulation
Atypical_PIKK_ATR_ATR_ST	Q9BXW9	FANCD2	Q13535	ATR	S717	S720L	720	Missense	distal	3	no	17.875	17.208	PhosphoSitePlus;EPSD	ICGC	10.658	Down-regulation
Atypical_PIKK_ATR_ATR_ST	Q9BXW9	FANCD2	Q13535	ATR	S1257	S1257A	1257	Missense	central	0	yes	14.367	0.000	EPSD	ICGC	10.658	Loss
Atypical_PIKK_ATR_ATR_ST	Q9BXW9	FANCD2	Q13535	ATR	S1401	Q1402H	1402	Missense	proximal	1	no	14.045	-3.473	EPSD	ICGC	10.658	Loss
Atypical_PIKK_ATR_ATR_ST	Q9BXW9	FANCD2	Q13535	ATR	S1401	I1399N	1399	Missense	proximal	-2	no	14.045	14.396	EPSD	ICGC;COSMIC	10.658	Up-regulation
Atypical_PIKK_ATR_ATR_ST	Q9BXW9	FANCD2	Q13535	ATR	S1401	L1394F	1394	Missense	distal	-7	no	14.045	14.102	EPSD	ICGC	10.658	Up-regulation
Atypical_PIKK_ATR_ATR_ST	Q9BXW9	FANCD2	Q13535	ATR	S1401	K1400N	1400	Missense	proximal	-1	no	14.045	14.629	EPSD	ICGC	10.658	Up-regulation
Atypical_PIKK_ATR_ATR_ST	Q9BXW9	FANCD2	Q13535	ATR	S1404	Q1402H	1402	Missense	proximal	-2	no	15.589	15.221	EPSD	ICGC	10.658	Down-regulation
Atypical_PIKK_ATR_ATR_ST	Q9BXW9	FANCD2	Q13535	ATR	S1404	I1399N	1399	Missense	distal	-5	no	15.589	15.528	EPSD	ICGC;COSMIC	10.658	Down-regulation
Atypical_PIKK_ATR_ATR_ST	Q9BXW9	FANCD2	Q13535	ATR	S1404	K1400N	1400	Missense	distal	-4	no	15.589	15.208	EPSD	ICGC	10.658	Down-regulation
Atypical_PIKK_ATR_ATR_ST	Q9BXW9	FANCD2	Q13535	ATR	S1404	E1411G	1411	Missense	distal	7	no	15.589	15.593	EPSD	ICGC	10.658	Up-regulation
Atypical_PIKK_ATR_ATR_ST	Q9BXW9	FANCD2	Q13535	ATR	S1404	E1411D	1411	Missense	distal	7	no	15.589	15.784	EPSD	ICGC;COSMIC	10.658	Up-regulation
Atypical_PIKK_ATR_ATR_ST	Q9BXW9	FANCD2	Q13535	ATR	S1418	E1411G	1411	Missense	distal	-7	no	14.007	13.930	EPSD	ICGC	10.658	Down-regulation
Atypical_PIKK_ATR_ATR_ST	Q9BXW9	FANCD2	Q13535	ATR	S1418	K1422N	1422	Missense	distal	4	no	14.007	14.776	EPSD	ICGC	10.658	Up-regulation
Atypical_PIKK_ATR_ATR_ST	Q9BXW9	FANCD2	Q13535	ATR	S1418	E1411D	1411	Missense	distal	-7	no	14.007	13.962	EPSD	ICGC;COSMIC	10.658	Down-regulation
Atypical_PIKK_ATR_ATR_ST	Q9BXW9	FANCD2	Q13535	ATR	S1443	G1437E	1437	Missense	distal	-6	no	10.977	11.002	EPSD	ICGC	10.658	Up-regulation
Atypical_PIKK_ATR_ATR_ST	Q9BXW9	FANCD2	Q13535	ATR	S1443	E1445A	1445	Missense	proximal	2	no	10.977	10.056	EPSD	ICGC;COSMIC	10.658	Loss
Atypical_PIKK_ATR_ATR_ST	P06748	NPM1	Q13535	ATR	S43	Q41H	41	Missense	proximal	-2	no	12.372	12.004	EPSD	ICGC	10.658	Down-regulation
Atypical_PIKK_ATR_ATR_ST	P06748	NPM1	Q13535	ATR	S43	L42S	42	Missense	proximal	-1	no	12.372	12.136	EPSD	ICGC;COSMIC	10.658	Down-regulation
Atypical_PIKK_ATR_ATR_ST	P06748	NPM1	Q13535	ATR	S125	E131D	131	Missense	distal	6	no	14.864	14.590	PhosphoSitePlus	ICGC;COSMIC	10.658	Down-regulation
Atypical_PIKK_ATR_ATR_ST	P06748	NPM1	Q13535	ATR	T199	R197G	197	Missense	proximal	-2	no	10.691	10.594	EPSD	ICGC;COSMIC	10.658	Loss
Atypical_PIKK_ATR_ATR_ST	P06748	NPM1	Q13535	ATR	T199	A204T	204	Missense	distal	5	no	10.691	10.688	EPSD	ICGC;COSMIC	10.658	Down-regulation
Atypical_PIKK_ATR_ATR_ST	P06748	NPM1	Q13535	ATR	T199	P200A	200	Missense	proximal	1	no	10.691	4.831	EPSD	ICGC	10.658	Loss
Atypical_PIKK_ATR_ATR_ST	P15927	RPA2	Q13535	ATR	T21	A17E	17	Missense	distal	-4	no	16.057	16.550	EPSD;PhosphoSitePlus	ICGC	10.658	Up-regulation
Atypical_PIKK_ATR_ATR_ST	P15927	RPA2	Q13535	ATR	S23	A17E	17	Missense	distal	-6	no	11.157	11.105	EPSD	ICGC	10.658	Down-regulation
Atypical_PIKK_ATR_ATR_ST	P15927	RPA2	Q13535	ATR	S114	D111Y	111	Missense	distal	-3	no	12.522	12.566	EPSD	ICGC;COSMIC	10.658	Up-regulation
Atypical_PIKK_ATR_ATR_ST	Q9NZC9	SMARCAL1	Q13535	ATR	S115	R114H	114	Missense	proximal	-1	no	11.322	11.216	EPSD	ICGC;COSMIC	10.658	Down-regulation
Atypical_PIKK_ATR_ATR_ST	Q9NZC9	SMARCAL1	Q13535	ATR	S115	G110D	110	Missense	distal	-5	no	11.322	11.475	EPSD	ICGC;COSMIC	10.658	Up-regulation
Atypical_PIKK_ATR_ATR_ST	Q9NZC9	SMARCAL1	Q13535	ATR	S115	S112N	112	Missense	distal	-3	no	11.322	12.407	EPSD	ICGC;COSMIC	10.658	Up-regulation
Atypical_PIKK_ATR_ATR_ST	Q9NZC9	SMARCAL1	Q13535	ATR	S129	P130T	130	Missense	proximal	1	no	11.361	6.710	EPSD	ICGC;COSMIC	10.658	Loss
Atypical_PIKK_ATR_ATR_ST	Q9NZC9	SMARCAL1	Q13535	ATR	S129	A127S	127	Missense	proximal	-2	no	11.361	10.585	EPSD	ICGC	10.658	Loss
Atypical_PIKK_ATR_ATR_ST	Q9NZC9	SMARCAL1	Q13535	ATR	S140	E142D	142	Missense	proximal	2	no	10.983	9.307	EPSD	ICGC;COSMIC	10.658	Loss
Atypical_PIKK_ATR_ATR_ST	Q9NZC9	SMARCAL1	Q13535	ATR	S173	S173Y	173	Missense	central	0	yes	13.969	0.000	EPSD	ICGC;COSMIC	10.658	Loss
Atypical_PIKK_ATR_ATR_ST	Q9NZC9	SMARCAL1	Q13535	ATR	S180	S173Y	173	Missense	distal	-7	no	10.862	10.689	EPSD	ICGC;COSMIC	10.658	Down-regulation
Atypical_PIKK_ATR_ATR_ST	Q9NZC9	SMARCAL1	Q13535	ATR	S627	L633R	633	Missense	distal	6	no	11.757	11.585	EPSD	ICGC;COSMIC	10.658	Down-regulation
Atypical_PIKK_ATR_ATR_ST	Q9NZC9	SMARCAL1	Q13535	ATR	S627	L630M	630	Missense	distal	3	no	11.757	11.733	EPSD	ICGC;COSMIC	10.658	Down-regulation
Atypical_PIKK_ATR_ATR_ST	Q9NZC9	SMARCAL1	Q13535	ATR	S627	W622L	622	Missense	distal	-5	no	11.757	11.727	EPSD	ICGC;COSMIC	10.658	Down-regulation
Atypical_PIKK_ATR_ATR_ST	Q9NZC9	SMARCAL1	Q13535	ATR	S652	R645L	645	Missense	distal	-7	no	14.972	14.854	PhosphoSitePlus	ICGC	10.658	Down-regulation
Atypical_PIKK_ATR_ATR_ST	Q14683	SMC1A	Q13535	ATR	S85	A89D	89	Missense	distal	4	no	11.105	10.751	EPSD	ICGC	10.658	Down-regulation
Atypical_PIKK_ATR_ATR_ST	Q14683	SMC1A	Q13535	ATR	S289	E290Q	290	Missense	proximal	1	no	8.406	14.326	EPSD	ICGC;COSMIC	10.658	Gain
Atypical_PIKK_ATR_ATR_ST	Q14683	SMC1A	Q13535	ATR	S358	G362R	362	Missense	distal	4	no	15.528	14.812	EPSD	ICGC	10.658	Down-regulation
Atypical_PIKK_ATR_ATR_ST	Q14683	SMC1A	Q13535	ATR	S360	G362R	362	Missense	proximal	2	no	13.881	12.669	EPSD	ICGC	10.658	Down-regulation
Atypical_PIKK_ATR_ATR_ST	Q14683	SMC1A	Q13535	ATR	S703	A705D	705	Missense	proximal	2	no	14.499	13.744	EPSD	ICGC	10.658	Down-regulation
Atypical_PIKK_ATR_ATR_ST	Q14683	SMC1A	Q13535	ATR	S703	Q702H	702	Missense	proximal	-1	no	14.499	14.463	EPSD	ICGC;COSMIC	10.658	Down-regulation
Atypical_PIKK_ATR_ATR_ST	Q14683	SMC1A	Q13535	ATR	S715	R711L	711	Missense	distal	-4	no	12.596	12.019	EPSD	ICGC;COSMIC	10.658	Down-regulation
Atypical_PIKK_ATR_ATR_ST	Q14683	SMC1A	Q13535	ATR	S951	S956I	956	Missense	distal	5	no	15.340	15.352	EPSD	ICGC;COSMIC	10.658	Up-regulation
Atypical_PIKK_ATR_ATR_ST	Q14683	SMC1A	Q13535	ATR	S957	S956I	956	Missense	proximal	-1	no	17.580	17.853	PhosphoSitePlus;EPSD	ICGC;COSMIC	10.658	Up-regulation
Atypical_PIKK_ATR_ATR_ST	Q14683	SMC1A	Q13535	ATR	S1188	V1186I	1186	Missense	proximal	-2	no	11.903	12.144	EPSD	ICGC;COSMIC	10.658	Up-regulation
Atypical_PIKK_ATR_ATR_ST	P54132	BLM	Q13535	ATR	T20	K24T	24	Missense	distal	4	no	10.871	11.053	EPSD	ICGC	10.658	Up-regulation
Atypical_PIKK_ATR_ATR_ST	P54132	BLM	Q13535	ATR	T20	L13I	13	Missense	distal	-7	no	10.871	10.919	EPSD	ICGC;COSMIC	10.658	Up-regulation
Atypical_PIKK_ATR_ATR_ST	P54132	BLM	Q13535	ATR	T99	P94S	94	Missense	distal	-5	no	15.027	14.998	EPSD;PhosphoSitePlus	ICGC	10.658	Down-regulation
Atypical_PIKK_ATR_ATR_ST	P54132	BLM	Q13535	ATR	S449	N454T	454	Missense	distal	5	no	11.788	11.792	EPSD	ICGC	10.658	Up-regulation
Atypical_PIKK_ATR_ATR_ST	P54132	BLM	Q13535	ATR	S449	S449C	449	Missense	central	0	yes	11.788	0.000	EPSD	ICGC;COSMIC	10.658	Loss
Atypical_PIKK_ATR_ATR_ST	P54132	BLM	Q13535	ATR	S449	M450I	450	Missense	proximal	1	no	11.788	8.384	EPSD	ICGC;COSMIC	10.658	Loss
Atypical_PIKK_ATR_ATR_ST	P54132	BLM	Q13535	ATR	S460	N454T	454	Missense	distal	-6	no	10.853	10.872	EPSD	ICGC	10.658	Up-regulation
Atypical_PIKK_ATR_ATR_ST	P54132	BLM	Q13535	ATR	S706	A703V	703	Missense	distal	-3	no	13.852	13.453	EPSD	ICGC;COSMIC	10.658	Down-regulation
Atypical_PIKK_ATR_ATR_ST	P54132	BLM	Q13535	ATR	S706	V705I	705	Missense	proximal	-1	no	13.852	14.104	EPSD	ICGC	10.658	Up-regulation
Atypical_PIKK_ATR_ATR_ST	P54132	BLM	Q13535	ATR	S706	V705F	705	Missense	proximal	-1	no	13.852	13.834	EPSD	ICGC;COSMIC	10.658	Down-regulation
Atypical_PIKK_ATR_ATR_ST	P54132	BLM	Q13535	ATR	S706	C704F	704	Missense	proximal	-2	no	13.852	13.812	EPSD	ICGC	10.658	Down-regulation
Atypical_PIKK_ATR_ATR_ST	P54132	BLM	Q13535	ATR	S706	T710N	710	Missense	distal	4	no	13.852	14.439	EPSD	ICGC	10.658	Up-regulation
Atypical_PIKK_ATR_ATR_ST	P54132	BLM	Q13535	ATR	S706	S706Y	706	Missense	central	0	yes	13.852	0.000	EPSD	ICGC	10.658	Loss
Atypical_PIKK_ATR_ATR_ST	P54132	BLM	Q13535	ATR	S706	P707S	707	Missense	proximal	1	no	13.852	12.743	EPSD	ICGC;COSMIC;GDSC	10.658	Down-regulation
Atypical_PIKK_ATR_ATR_ST	P54132	BLM	Q13535	ATR	T832	A833S	833	Missense	proximal	1	no	7.024	11.774	EPSD	ICGC	10.658	Gain
Atypical_PIKK_ATR_ATR_ST	P54132	BLM	Q13535	ATR	T907	Q909H	909	Missense	proximal	2	no	12.034	11.714	EPSD	ICGC	10.658	Down-regulation
Atypical_PIKK_ATR_ATR_ST	P54132	BLM	Q13535	ATR	T907	Q909R	909	Missense	proximal	2	no	12.034	11.946	EPSD	ICGC;COSMIC	10.658	Down-regulation
Atypical_PIKK_ATR_ATR_ST	P54132	BLM	Q13535	ATR	T907	T907M	907	Missense	central	0	yes	12.034	0.000	EPSD	ICGC;COSMIC	10.658	Loss
Atypical_PIKK_ATR_ATR_ST	P54132	BLM	Q13535	ATR	S1296	P1297Q	1297	Missense	proximal	1	no	8.039	12.906	EPSD	ICGC;COSMIC	10.658	Gain
Atypical_PIKK_ATR_ATR_ST	P54132	BLM	Q13535	ATR	S1304	P1297Q	1297	Missense	distal	-7	no	13.149	13.106	EPSD	ICGC;COSMIC	10.658	Down-regulation
Atypical_PIKK_ATR_ATR_ST	Q8IX01	SUGP2	Q13535	ATR	T7	A3T	3	Missense	distal	-4	no	17.875	17.268	PhosphoSitePlus	ICGC;COSMIC	10.658	Down-regulation
Atypical_PIKK_ATR_ATR_ST	Q8IX01	SUGP2	Q13535	ATR	S59	H58N	58	Missense	proximal	-1	no	10.859	11.315	EPSD	ICGC	10.658	Up-regulation
Atypical_PIKK_ATR_ATR_ST	Q8IX01	SUGP2	Q13535	ATR	S59	Y63C	63	Missense	distal	4	no	10.859	11.094	EPSD	ICGC;GDSC;CCLE	10.658	Up-regulation
Atypical_PIKK_ATR_ATR_ST	Q8IX01	SUGP2	Q13535	ATR	S59	V57I	57	Missense	proximal	-2	no	10.859	11.100	EPSD	ICGC;COSMIC	10.658	Up-regulation
Atypical_PIKK_ATR_ATR_ST	Q8IX01	SUGP2	Q13535	ATR	S93	N94S	94	Missense	proximal	1	no	12.289	10.588	EPSD	ICGC;COSMIC	10.658	Loss
Atypical_PIKK_ATR_ATR_ST	Q8IX01	SUGP2	Q13535	ATR	S93	N94K	94	Missense	proximal	1	no	12.289	5.598	EPSD	ICGC	10.658	Loss
Atypical_PIKK_ATR_ATR_ST	Q8IX01	SUGP2	Q13535	ATR	S98	N94S	94	Missense	distal	-4	no	10.961	10.738	EPSD	ICGC;COSMIC	10.658	Down-regulation
Atypical_PIKK_ATR_ATR_ST	Q8IX01	SUGP2	Q13535	ATR	S98	N94K	94	Missense	distal	-4	no	10.961	11.342	EPSD	ICGC	10.658	Up-regulation
Atypical_PIKK_ATR_ATR_ST	Q8IX01	SUGP2	Q13535	ATR	S133	R126W	126	Missense	distal	-7	no	12.685	12.627	EPSD	ICGC;COSMIC	10.658	Down-regulation
Atypical_PIKK_ATR_ATR_ST	Q8IX01	SUGP2	Q13535	ATR	S133	R132H	132	Missense	proximal	-1	no	12.685	12.579	EPSD	ICGC	10.658	Down-regulation
Atypical_PIKK_ATR_ATR_ST	Q8IX01	SUGP2	Q13535	ATR	S159	G165S	165	Missense	distal	6	no	13.745	13.987	EPSD	ICGC	10.658	Up-regulation
Atypical_PIKK_ATR_ATR_ST	Q8IX01	SUGP2	Q13535	ATR	S251	L247F	247	Missense	distal	-4	no	10.692	11.283	EPSD	ICGC;COSMIC	10.658	Up-regulation
Atypical_PIKK_ATR_ATR_ST	Q8IX01	SUGP2	Q13535	ATR	T265	N269D	269	Missense	distal	4	no	11.723	11.033	EPSD	ICGC;COSMIC	10.658	Down-regulation
Atypical_PIKK_ATR_ATR_ST	Q8IX01	SUGP2	Q13535	ATR	T265	I261L	261	Missense	distal	-4	no	11.723	12.190	EPSD	ICGC;COSMIC	10.658	Up-regulation
Atypical_PIKK_ATR_ATR_ST	Q8IX01	SUGP2	Q13535	ATR	T284	T281I	281	Missense	distal	-3	no	10.718	10.464	EPSD	ICGC;COSMIC	10.658	Loss
Atypical_PIKK_ATR_ATR_ST	Q8IX01	SUGP2	Q13535	ATR	S537	L531P	531	Missense	distal	-6	no	12.052	11.988	EPSD	ICGC;COSMIC	10.658	Down-regulation
Atypical_PIKK_ATR_ATR_ST	Q8IX01	SUGP2	Q13535	ATR	S573	P579T	579	Missense	distal	6	no	10.558	10.808	EPSD	ICGC	10.658	Gain
Atypical_PIKK_ATR_ATR_ST	Q8IX01	SUGP2	Q13535	ATR	S641	R639Q	639	Missense	proximal	-2	no	10.875	10.797	EPSD	ICGC;COSMIC	10.658	Down-regulation
Atypical_PIKK_ATR_ATR_ST	Q8IX01	SUGP2	Q13535	ATR	S721	R715Q	715	Missense	distal	-6	no	16.167	16.159	EPSD	ICGC;COSMIC	10.658	Down-regulation
Atypical_PIKK_ATR_ATR_ST	Q8IX01	SUGP2	Q13535	ATR	S721	P728Q	728	Missense	distal	7	no	16.167	16.026	EPSD	ICGC	10.658	Down-regulation
Atypical_PIKK_ATR_ATR_ST	Q8IX01	SUGP2	Q13535	ATR	S721	P718T	718	Missense	distal	-3	no	16.167	16.169	EPSD	ICGC	10.658	Up-regulation
Atypical_PIKK_ATR_ATR_ST	Q8IX01	SUGP2	Q13535	ATR	S940	A938V	938	Missense	proximal	-2	no	14.359	13.839	EPSD	ICGC;COSMIC	10.658	Down-regulation
Atypical_PIKK_ATR_ATR_ST	Q8IX01	SUGP2	Q13535	ATR	S940	L933M	933	Missense	distal	-7	no	14.359	14.512	EPSD	ICGC	10.658	Up-regulation
Atypical_PIKK_ATR_ATR_ST	Q8IX01	SUGP2	Q13535	ATR	S1047	G1044E	1044	Missense	distal	-3	no	11.321	11.480	EPSD	ICGC;COSMIC	10.658	Up-regulation
Atypical_PIKK_ATR_ATR_ST	Q8IX01	SUGP2	Q13535	ATR	S1047	A1054D	1054	Missense	distal	7	no	11.321	11.407	EPSD	ICGC;COSMIC	10.658	Up-regulation
Atypical_PIKK_ATR_ATR_ST	Q8IX01	SUGP2	Q13535	ATR	S1047	G1044V	1044	Missense	distal	-3	no	11.321	11.720	EPSD	ICGC;COSMIC	10.658	Up-regulation
Atypical_PIKK_ATR_ATR_ST	Q9H6E5	TUT1	Q13535	ATR	S10	S6L	6	Missense	distal	-4	no	11.244	10.369	EPSD	ICGC;COSMIC	10.658	Loss
Atypical_PIKK_ATR_ATR_ST	Q9H6E5	TUT1	Q13535	ATR	S10	D5G	5	Missense	distal	-5	no	11.244	11.092	EPSD	ICGC;COSMIC	10.658	Down-regulation
Atypical_PIKK_ATR_ATR_ST	Q9H6E5	TUT1	Q13535	ATR	S10	E9K	9	Missense	proximal	-1	no	11.244	10.995	EPSD	ICGC	10.658	Down-regulation
Atypical_PIKK_ATR_ATR_ST	Q9H6E5	TUT1	Q13535	ATR	S10	F16V	16	Missense	distal	6	no	11.244	11.290	EPSD	ICGC	10.658	Up-regulation
Atypical_PIKK_ATR_ATR_ST	Q9H6E5	TUT1	Q13535	ATR	S238	S240L	240	Missense	proximal	2	no	13.187	12.221	EPSD	ICGC	10.658	Down-regulation
Atypical_PIKK_ATR_ATR_ST	Q9H6E5	TUT1	Q13535	ATR	S238	D242E	242	Missense	distal	4	no	13.187	12.997	EPSD	ICGC;COSMIC	10.658	Down-regulation
Atypical_PIKK_ATR_ATR_ST	Q9H6E5	TUT1	Q13535	ATR	S238	D242N	242	Missense	distal	4	no	13.187	13.876	EPSD	ICGC	10.658	Up-regulation
Atypical_PIKK_ATR_ATR_ST	Q9H6E5	TUT1	Q13535	ATR	S240	S240L	240	Missense	central	0	yes	11.275	0.000	EPSD	ICGC	10.658	Loss
Atypical_PIKK_ATR_ATR_ST	Q9H6E5	TUT1	Q13535	ATR	S240	D242E	242	Missense	proximal	2	no	11.275	12.950	EPSD	ICGC;COSMIC	10.658	Up-regulation
Atypical_PIKK_ATR_ATR_ST	Q9H6E5	TUT1	Q13535	ATR	S240	D242N	242	Missense	proximal	2	no	11.275	12.195	EPSD	ICGC	10.658	Up-regulation
Atypical_PIKK_ATR_ATR_ST	Q9H6E5	TUT1	Q13535	ATR	T329	P330Q	330	Missense	proximal	1	no	10.055	14.922	EPSD	ICGC;COSMIC	10.658	Gain
Atypical_PIKK_ATR_ATR_ST	Q9H6E5	TUT1	Q13535	ATR	T642	R643Q	643	Missense	proximal	1	no	5.306	12.302	EPSD	ICGC;COSMIC	10.658	Gain
Atypical_PIKK_ATR_ATR_ST	Q9H6E5	TUT1	Q13535	ATR	S652	Q654E	654	Missense	proximal	2	no	10.275	11.529	EPSD	ICGC;COSMIC	10.658	Gain
Atypical_PIKK_ATR_ATR_ST	Q9H6E5	TUT1	Q13535	ATR	S653	Q654E	654	Missense	proximal	1	no	10.689	4.769	EPSD	ICGC;COSMIC	10.658	Loss
Atypical_PIKK_ATR_ATR_ST	Q9H6E5	TUT1	Q13535	ATR	S707	G712E	712	Missense	distal	5	no	12.483	12.473	EPSD	ICGC;COSMIC	10.658	Down-regulation
Atypical_PIKK_ATR_ATR_ST	Q9H6E5	TUT1	Q13535	ATR	S707	A704T	704	Missense	distal	-3	no	12.483	11.922	EPSD	ICGC;COSMIC	10.658	Down-regulation
Atypical_PIKK_ATR_ATR_ST	Q9H6E5	TUT1	Q13535	ATR	S750	A745T	745	Missense	distal	-5	no	15.883	15.800	PhosphoSitePlus	ICGC;COSMIC	10.658	Down-regulation
Atypical_PIKK_ATR_ATR_ST	Q13315	ATM	Q13535	ATR	T86	V82L	82	Missense	distal	-4	no	15.019	14.612	EPSD	ICGC	10.658	Down-regulation
Atypical_PIKK_ATR_ATR_ST	Q13315	ATM	Q13535	ATR	T86	Q91H	91	Missense	distal	5	no	15.019	15.023	EPSD	ICGC;COSMIC	10.658	Up-regulation
Atypical_PIKK_ATR_ATR_ST	Q13315	ATM	Q13535	ATR	S99	Y103D	103	Missense	distal	4	no	11.150	10.643	EPSD	ICGC;COSMIC	10.658	Loss
Atypical_PIKK_ATR_ATR_ST	Q13315	ATM	Q13535	ATR	S99	V101F	101	Missense	proximal	2	no	11.150	7.825	EPSD	ICGC	10.658	Loss
Atypical_PIKK_ATR_ATR_ST	Q13315	ATM	Q13535	ATR	S200	G204V	204	Missense	distal	4	no	13.414	12.807	EPSD	ICGC;COSMIC	10.658	Down-regulation
Atypical_PIKK_ATR_ATR_ST	Q13315	ATM	Q13535	ATR	T297	Q298K	298	Missense	proximal	1	no	13.489	2.523	EPSD	ICGC;COSMIC	10.658	Loss
Atypical_PIKK_ATR_ATR_ST	Q13315	ATM	Q13535	ATR	S333	S333F	333	Missense	central	0	yes	11.120	0.000	EPSD	ICGC;COSMIC	10.658	Loss
Atypical_PIKK_ATR_ATR_ST	Q13315	ATM	Q13535	ATR	S363	N358I	358	Missense	distal	-5	no	13.259	13.320	EPSD	ICGC;COSMIC	10.658	Up-regulation
Atypical_PIKK_ATR_ATR_ST	Q13315	ATM	Q13535	ATR	S363	L364F	364	Missense	proximal	1	no	13.259	12.008	EPSD	ICGC;COSMIC	10.658	Down-regulation
Atypical_PIKK_ATR_ATR_ST	Q13315	ATM	Q13535	ATR	S363	D360Y	360	Missense	distal	-3	no	13.259	13.302	EPSD	ICGC;COSMIC	10.658	Up-regulation
Atypical_PIKK_ATR_ATR_ST	Q13315	ATM	Q13535	ATR	S363	S367F	367	Missense	distal	4	no	13.259	13.278	EPSD	ICGC;COSMIC	10.658	Up-regulation
Atypical_PIKK_ATR_ATR_ST	Q13315	ATM	Q13535	ATR	S367	L364F	364	Missense	distal	-3	no	10.982	11.270	EPSD	ICGC;COSMIC	10.658	Up-regulation
Atypical_PIKK_ATR_ATR_ST	Q13315	ATM	Q13535	ATR	S367	D360Y	360	Missense	distal	-7	no	10.982	10.825	EPSD	ICGC;COSMIC	10.658	Down-regulation
Atypical_PIKK_ATR_ATR_ST	Q13315	ATM	Q13535	ATR	S367	S367F	367	Missense	central	0	yes	10.982	0.000	EPSD	ICGC;COSMIC	10.658	Loss
Atypical_PIKK_ATR_ATR_ST	Q13315	ATM	Q13535	ATR	T373	S378R	378	Missense	distal	5	no	14.349	14.359	EPSD	ICGC;COSMIC	10.658	Up-regulation
Atypical_PIKK_ATR_ATR_ST	Q13315	ATM	Q13535	ATR	T373	S367F	367	Missense	distal	-6	no	14.349	14.428	EPSD	ICGC;COSMIC	10.658	Up-regulation
Atypical_PIKK_ATR_ATR_ST	Q13315	ATM	Q13535	ATR	S440	Q441H	441	Missense	proximal	1	no	13.847	-3.671	EPSD	ICGC	10.658	Loss
Atypical_PIKK_ATR_ATR_ST	Q13315	ATM	Q13535	ATR	S646	V648L	648	Missense	proximal	2	no	11.541	9.939	EPSD	ICGC	10.658	Loss
Atypical_PIKK_ATR_ATR_ST	Q13315	ATM	Q13535	ATR	S1878	Q1879K	1879	Missense	proximal	1	no	13.195	2.229	EPSD	ICGC;COSMIC	10.658	Loss
Atypical_PIKK_ATR_ATR_ST	Q13315	ATM	Q13535	ATR	S1981	S1988I	1988	Missense	distal	7	no	15.195	15.514	PhosphoSitePlus	ICGC;COSMIC	10.658	Up-regulation
Atypical_PIKK_ATR_ATR_ST	Q13315	ATM	Q13535	ATR	S1981	E1979V	1979	Missense	proximal	-2	no	15.195	15.155	PhosphoSitePlus	ICGC	10.658	Down-regulation
Atypical_PIKK_ATR_ATR_ST	Q13315	ATM	Q13535	ATR	S2162	E2164D	2164	Missense	proximal	2	no	12.542	10.866	EPSD	ICGC;COSMIC	10.658	Down-regulation
Atypical_PIKK_ATR_ATR_ST	Q13315	ATM	Q13535	ATR	S2162	V2155M	2155	Missense	distal	-7	no	12.542	12.585	EPSD	ICGC;COSMIC	10.658	Up-regulation
Atypical_PIKK_ATR_ATR_ST	Q13315	ATM	Q13535	ATR	S2242	E2245Q	2245	Missense	distal	3	no	14.196	14.079	EPSD	ICGC;COSMIC	10.658	Down-regulation
Atypical_PIKK_ATR_ATR_ST	Q13315	ATM	Q13535	ATR	S2592	D2597N	2597	Missense	distal	5	no	13.565	13.561	EPSD	ICGC;COSMIC	10.658	Down-regulation
Atypical_PIKK_ATR_ATR_ST	P16220	CREB1	Q13535	ATR	S143	D140A	140	Missense	distal	-3	no	12.724	12.770	EPSD	ICGC;COSMIC	10.658	Up-regulation
Atypical_PIKK_ATR_ATR_ST	O96017	CHEK2	Q13535	ATR	S33	G37C	37	Missense	distal	4	no	12.947	12.867	EPSD	ICGC;COSMIC	10.658	Down-regulation
Atypical_PIKK_ATR_ATR_ST	O96017	CHEK2	Q13535	ATR	S35	G37C	37	Missense	proximal	2	no	15.081	12.458	EPSD	ICGC;COSMIC	10.658	Down-regulation
Atypical_PIKK_ATR_ATR_ST	O96017	CHEK2	Q13535	ATR	S50	M46I	46	Missense	distal	-4	no	15.918	14.795	EPSD	ICGC;COSMIC	10.658	Down-regulation
Atypical_PIKK_ATR_ATR_ST	O96017	CHEK2	Q13535	ATR	S50	S49F	49	Missense	proximal	-1	no	15.918	15.919	EPSD	ICGC;COSMIC	10.658	Up-regulation
Atypical_PIKK_ATR_ATR_ST	O96017	CHEK2	Q13535	ATR	S50	T45M	45	Missense	distal	-5	no	15.918	15.802	EPSD	ICGC;COSMIC	10.658	Down-regulation
Atypical_PIKK_ATR_ATR_ST	O96017	CHEK2	Q13535	ATR	S357	E359K	359	Missense	proximal	2	no	12.798	11.849	EPSD	ICGC;COSMIC	10.658	Down-regulation
Atypical_PIKK_ATR_ATR_ST	O96017	CHEK2	Q13535	ATR	S357	L363F	363	Missense	distal	6	no	12.798	12.865	EPSD	ICGC;COSMIC	10.658	Up-regulation
Atypical_PIKK_ATR_ATR_ST	O96017	CHEK2	Q13535	ATR	S357	L355R	355	Missense	proximal	-2	no	12.798	12.505	EPSD	ICGC	10.658	Down-regulation
Atypical_PIKK_ATR_ATR_ST	O96017	CHEK2	Q13535	ATR	S357	E351D	351	Missense	distal	-6	no	12.798	12.806	EPSD	ICGC;COSMIC	10.658	Up-regulation
Atypical_PIKK_ATR_ATR_ST	O96017	CHEK2	Q13535	ATR	S357	L354V	354	Missense	distal	-3	no	12.798	12.667	EPSD	ICGC;COSMIC	10.658	Down-regulation
Atypical_PIKK_ATR_ATR_ST	O96017	CHEK2	Q13535	ATR	T432	Q433E	433	Missense	proximal	1	no	11.577	5.656	EPSD	ICGC;COSMIC	10.658	Loss
Atypical_PIKK_ATR_ATR_ST	O96017	CHEK2	Q13535	ATR	T432	S428F	428	Missense	distal	-4	no	11.577	11.294	EPSD	ICGC;COSMIC	10.658	Down-regulation
Atypical_PIKK_ATR_ATR_ST	O96017	CHEK2	Q13535	ATR	T432	H430Y	430	Missense	proximal	-2	no	11.577	12.452	EPSD	ICGC;COSMIC	10.658	Up-regulation
Atypical_PIKK_ATR_ATR_ST	O96017	CHEK2	Q13535	ATR	S500	A507V	507	Missense	distal	7	no	11.225	11.365	EPSD	ICGC	10.658	Up-regulation
Atypical_PIKK_ATR_ATR_ST	O96017	CHEK2	Q13535	ATR	S500	Q496P	496	Missense	distal	-4	no	11.225	11.666	EPSD	ICGC;COSMIC	10.658	Up-regulation
Atypical_PIKK_ATR_ATR_ST	O96017	CHEK2	Q13535	ATR	S500	F495I	495	Missense	distal	-5	no	11.225	11.202	EPSD	ICGC;COSMIC	10.658	Down-regulation
Atypical_PIKK_ATR_ATR_ST	Q13535	ATR	Q13535	ATR	S61	P63Q	63	Missense	proximal	2	no	13.209	12.708	EPSD	ICGC	10.658	Down-regulation
Atypical_PIKK_ATR_ATR_ST	Q13535	ATR	Q13535	ATR	S61	M67T	67	Missense	distal	6	no	13.209	13.502	EPSD	ICGC;COSMIC	10.658	Up-regulation
Atypical_PIKK_ATR_ATR_ST	Q13535	ATR	Q13535	ATR	T952	P953Q	953	Missense	proximal	1	no	7.043	11.911	EPSD	ICGC	10.658	Gain
Atypical_PIKK_ATR_ATR_ST	Q13535	ATR	Q13535	ATR	S1333	T1337A	1337	Missense	distal	4	no	14.151	14.402	EPSD	ICGC	10.658	Up-regulation
Atypical_PIKK_ATR_ATR_ST	Q13535	ATR	Q13535	ATR	T1578	L1576I	1576	Missense	proximal	-2	no	12.280	12.074	EPSD	ICGC	10.658	Down-regulation
Atypical_PIKK_ATR_ATR_ST	Q13535	ATR	Q13535	ATR	T1589	H1594L	1594	Missense	distal	5	no	14.249	14.251	EPSD	ICGC;COSMIC	10.658	Up-regulation
Atypical_PIKK_ATR_ATR_ST	Q13535	ATR	Q13535	ATR	S1876	N1882S	1882	Missense	distal	6	no	11.526	11.412	EPSD	ICGC;COSMIC	10.658	Down-regulation
Atypical_PIKK_ATR_ATR_ST	Q13535	ATR	Q13535	ATR	S1876	H1870N	1870	Missense	distal	-6	no	11.526	11.504	EPSD	ICGC	10.658	Down-regulation
Atypical_PIKK_ATR_ATR_ST	Q13535	ATR	Q13535	ATR	S1876	L1881F	1881	Missense	distal	5	no	11.526	11.532	EPSD	ICGC	10.658	Up-regulation
Atypical_PIKK_ATR_ATR_ST	P35568	IRS1	Q13535	ATR	S24	K23N	23	Missense	proximal	-1	no	11.040	11.625	EPSD	ICGC;COSMIC	10.658	Up-regulation
Atypical_PIKK_ATR_ATR_ST	P35568	IRS1	Q13535	ATR	S36	E37Q	37	Missense	proximal	1	no	7.878	13.799	EPSD	ICGC;COSMIC;CCLE	10.658	Gain
Atypical_PIKK_ATR_ATR_ST	P35568	IRS1	Q13535	ATR	S99	F93L	93	Missense	distal	-6	no	10.841	10.871	EPSD	ICGC;COSMIC	10.658	Up-regulation
Atypical_PIKK_ATR_ATR_ST	P35568	IRS1	Q13535	ATR	S99	A96S	96	Missense	distal	-3	no	10.841	10.002	EPSD	ICGC	10.658	Loss
Atypical_PIKK_ATR_ATR_ST	P35568	IRS1	Q13535	ATR	S99	A101S	101	Missense	proximal	2	no	10.841	10.694	EPSD	ICGC;COSMIC	10.658	Down-regulation
Atypical_PIKK_ATR_ATR_ST	P35568	IRS1	Q13535	ATR	S270	R265H	265	Missense	distal	-5	no	14.440	14.378	PhosphoSitePlus	ICGC	10.658	Down-regulation
Atypical_PIKK_ATR_ATR_ST	P35568	IRS1	Q13535	ATR	S270	F264L	264	Missense	distal	-6	no	14.440	14.470	PhosphoSitePlus	ICGC	10.658	Up-regulation
Atypical_PIKK_ATR_ATR_ST	P35568	IRS1	Q13535	ATR	S270	S272P	272	Missense	proximal	2	no	14.440	14.756	PhosphoSitePlus	ICGC	10.658	Up-regulation
Atypical_PIKK_ATR_ATR_ST	P35568	IRS1	Q13535	ATR	S270	S268I	268	Missense	proximal	-2	no	14.440	14.937	PhosphoSitePlus	ICGC;COSMIC	10.658	Up-regulation
Atypical_PIKK_ATR_ATR_ST	P35568	IRS1	Q13535	ATR	S277	S272P	272	Missense	distal	-5	no	14.052	14.082	EPSD	ICGC	10.658	Up-regulation
Atypical_PIKK_ATR_ATR_ST	P35568	IRS1	Q13535	ATR	S277	N278T	278	Missense	proximal	1	no	14.052	8.810	EPSD	ICGC	10.658	Loss
Atypical_PIKK_ATR_ATR_ST	P35568	IRS1	Q13535	ATR	S295	P293L	293	Missense	proximal	-2	no	15.361	16.012	EPSD	ICGC;COSMIC	10.658	Up-regulation
Atypical_PIKK_ATR_ATR_ST	P35568	IRS1	Q13535	ATR	S295	P292L	292	Missense	distal	-3	no	15.361	15.656	EPSD	ICGC	10.658	Up-regulation
Atypical_PIKK_ATR_ATR_ST	P35568	IRS1	Q13535	ATR	S295	T300P	300	Missense	distal	5	no	15.361	15.364	EPSD	ICGC;COSMIC;GDSC	10.658	Up-regulation
Atypical_PIKK_ATR_ATR_ST	P35568	IRS1	Q13535	ATR	S295	V297G	297	Missense	proximal	2	no	15.361	15.663	EPSD	ICGC;COSMIC	10.658	Up-regulation
Atypical_PIKK_ATR_ATR_ST	P35568	IRS1	Q13535	ATR	S315	G319R	319	Missense	distal	4	no	10.769	10.052	EPSD	ICGC;COSMIC	10.658	Loss
Atypical_PIKK_ATR_ATR_ST	P35568	IRS1	Q13535	ATR	S345	S345N	345	Missense	central	0	yes	11.532	0.000	EPSD	ICGC	10.658	Loss
Atypical_PIKK_ATR_ATR_ST	P35568	IRS1	Q13535	ATR	T354	H355Q	355	Missense	proximal	1	no	-3.108	14.410	EPSD	ICGC	10.658	Gain
Atypical_PIKK_ATR_ATR_ST	P35568	IRS1	Q13535	ATR	T397	S402C	402	Missense	distal	5	no	10.745	10.771	EPSD	ICGC;COSMIC	10.658	Up-regulation
Atypical_PIKK_ATR_ATR_ST	P35568	IRS1	Q13535	ATR	T397	S393T	393	Missense	distal	-4	no	10.745	10.658	EPSD	ICGC;COSMIC	10.658	Down-regulation
Atypical_PIKK_ATR_ATR_ST	P35568	IRS1	Q13535	ATR	T397	S396G	396	Missense	proximal	-1	no	10.745	10.838	EPSD	ICGC;CCLE	10.658	Up-regulation
Atypical_PIKK_ATR_ATR_ST	P35568	IRS1	Q13535	ATR	S413	A414D	414	Missense	proximal	1	no	7.076	12.389	EPSD	ICGC	10.658	Gain
Atypical_PIKK_ATR_ATR_ST	P35568	IRS1	Q13535	ATR	S449	A456D	456	Missense	distal	7	no	13.391	13.478	EPSD	ICGC;COSMIC	10.658	Up-regulation
Atypical_PIKK_ATR_ATR_ST	P35568	IRS1	Q13535	ATR	S463	R457H	457	Missense	distal	-6	no	13.218	13.224	EPSD	ICGC;COSMIC	10.658	Up-regulation
Atypical_PIKK_ATR_ATR_ST	P35568	IRS1	Q13535	ATR	S463	A456D	456	Missense	distal	-7	no	13.218	13.236	EPSD	ICGC;COSMIC	10.658	Up-regulation
Atypical_PIKK_ATR_ATR_ST	P35568	IRS1	Q13535	ATR	S547	P540S	540	Missense	distal	-7	no	11.112	11.084	EPSD	ICGC	10.658	Down-regulation
Atypical_PIKK_ATR_ATR_ST	P35568	IRS1	Q13535	ATR	S694	K697Q	697	Missense	distal	3	no	10.973	10.700	EPSD	ICGC;COSMIC	10.658	Down-regulation
Atypical_PIKK_ATR_ATR_ST	P35568	IRS1	Q13535	ATR	S694	S691F	691	Missense	distal	-3	no	10.973	11.832	EPSD	ICGC	10.658	Up-regulation
Atypical_PIKK_ATR_ATR_ST	P35568	IRS1	Q13535	ATR	S741	P746T	746	Missense	distal	5	no	10.880	10.877	EPSD	ICGC	10.658	Down-regulation
Atypical_PIKK_ATR_ATR_ST	P35568	IRS1	Q13535	ATR	S741	P746S	746	Missense	distal	5	no	10.880	10.868	EPSD	ICGC	10.658	Down-regulation
Atypical_PIKK_ATR_ATR_ST	P35568	IRS1	Q13535	ATR	S741	D748N	748	Missense	distal	7	no	10.880	11.104	EPSD	ICGC	10.658	Up-regulation
Atypical_PIKK_ATR_ATR_ST	P35568	IRS1	Q13535	ATR	S744	D748N	748	Missense	distal	4	no	10.255	10.945	EPSD	ICGC	10.658	Gain
Atypical_PIKK_ATR_ATR_ST	P35568	IRS1	Q13535	ATR	T1004	D1003N	1003	Missense	proximal	-1	no	11.315	11.605	EPSD	ICGC;COSMIC	10.658	Up-regulation
Atypical_PIKK_ATR_ATR_ST	P35568	IRS1	Q13535	ATR	S1131	D1137N	1137	Missense	distal	6	no	10.394	10.697	EPSD	ICGC	10.658	Gain
Atypical_PIKK_ATR_ATR_ST	P35568	IRS1	Q13535	ATR	T1196	Q1190K	1190	Missense	distal	-6	no	12.834	12.769	EPSD	ICGC	10.658	Down-regulation
Atypical_PIKK_ATR_ATR_ST	O75943	RAD17	Q13535	ATR	T304	T304A	304	Missense	central	0	yes	11.033	0.000	EPSD	ICGC;COSMIC	10.658	Loss
Atypical_PIKK_ATR_ATR_ST	Q14191	WRN	Q13535	ATR	T174	K168N	168	Missense	distal	-6	no	10.610	10.667	EPSD	ICGC	10.658	Gain
Atypical_PIKK_ATR_ATR_ST	Q14191	WRN	Q13535	ATR	S176	W175C	175	Missense	proximal	-1	no	10.842	11.169	EPSD	ICGC;COSMIC	10.658	Up-regulation
Atypical_PIKK_ATR_ATR_ST	Q14191	WRN	Q13535	ATR	S176	T174I	174	Missense	proximal	-2	no	10.842	11.037	EPSD	ICGC;COSMIC	10.658	Up-regulation
Atypical_PIKK_ATR_ATR_ST	Q14191	WRN	Q13535	ATR	S409	Q407P	407	Missense	proximal	-2	no	13.933	13.653	EPSD	ICGC	10.658	Down-regulation
Atypical_PIKK_ATR_ATR_ST	Q14191	WRN	Q13535	ATR	T461	Y463H	463	Missense	proximal	2	no	9.647	11.420	EPSD	ICGC;COSMIC	10.658	Gain
Atypical_PIKK_ATR_ATR_ST	Q14191	WRN	Q13535	ATR	S462	D460N	460	Missense	proximal	-2	no	10.649	11.106	EPSD	ICGC;COSMIC	10.658	Gain
Atypical_PIKK_ATR_ATR_ST	Q14191	WRN	Q13535	ATR	S462	T461M	461	Missense	proximal	-1	no	10.649	10.773	EPSD	ICGC;COSMIC	10.658	Gain
Atypical_PIKK_ATR_ATR_ST	Q14191	WRN	Q13535	ATR	S462	D460Y	460	Missense	proximal	-2	no	10.649	11.096	EPSD	ICGC;COSMIC	10.658	Gain
Atypical_PIKK_ATR_ATR_ST	Q14191	WRN	Q13535	ATR	S467	Y463H	463	Missense	distal	-4	no	8.684	10.783	EPSD	ICGC;COSMIC	10.658	Gain
Atypical_PIKK_ATR_ATR_ST	Q14191	WRN	Q13535	ATR	S478	E472D	472	Missense	distal	-6	no	12.861	12.868	EPSD	ICGC;COSMIC	10.658	Up-regulation
Atypical_PIKK_ATR_ATR_ST	Q14191	WRN	Q13535	ATR	S612	A616S	616	Missense	distal	4	no	10.833	10.531	EPSD	ICGC	10.658	Loss
Atypical_PIKK_ATR_ATR_ST	Q14191	WRN	Q13535	ATR	T777	L784P	784	Missense	distal	7	no	11.892	11.894	EPSD	ICGC;COSMIC	10.658	Up-regulation
Atypical_PIKK_ATR_ATR_ST	Q14191	WRN	Q13535	ATR	S1058	L1061I	1061	Missense	distal	3	no	14.323	14.999	EPSD	ICGC;COSMIC	10.658	Up-regulation
Atypical_PIKK_ATR_ATR_ST	Q14191	WRN	Q13535	ATR	S1378	C1374F	1374	Missense	distal	-4	no	11.754	12.760	EPSD	ICGC;COSMIC	10.658	Up-regulation
Atypical_PIKK_ATR_ATR_ST	Q14191	WRN	Q13535	ATR	S1399	T1398N	1398	Missense	proximal	-1	no	10.305	10.736	EPSD	ICGC	10.658	Gain
Atypical_PIKK_ATR_ATR_ST	P49736	MCM2	Q13535	ATR	S13	A11S	11	Missense	proximal	-2	no	11.448	10.672	EPSD	ICGC	10.658	Down-regulation
Atypical_PIKK_ATR_ATR_ST	P49736	MCM2	Q13535	ATR	S32	R33Q	33	Missense	proximal	1	no	6.250	13.245	EPSD	ICGC	10.658	Gain
Atypical_PIKK_ATR_ATR_ST	P49736	MCM2	Q13535	ATR	T39	R33Q	33	Missense	distal	-6	no	11.507	11.499	EPSD	ICGC	10.658	Down-regulation
Atypical_PIKK_ATR_ATR_ST	P49736	MCM2	Q13535	ATR	T39	S40P	40	Missense	proximal	1	no	11.507	12.617	EPSD	ICGC;COSMIC	10.658	Up-regulation
Atypical_PIKK_ATR_ATR_ST	P49736	MCM2	Q13535	ATR	S41	S40P	40	Missense	proximal	-1	no	13.128	13.342	EPSD	ICGC;COSMIC	10.658	Up-regulation
Atypical_PIKK_ATR_ATR_ST	P49736	MCM2	Q13535	ATR	S108	A107S	107	Missense	proximal	-1	no	15.987	15.711	PhosphoSitePlus	ICGC	10.658	Down-regulation
Atypical_PIKK_ATR_ATR_ST	P49736	MCM2	Q13535	ATR	S108	R115Q	115	Missense	distal	7	no	15.987	15.786	PhosphoSitePlus	ICGC;COSMIC	10.658	Down-regulation
Atypical_PIKK_ATR_ATR_ST	P49736	MCM2	Q13535	ATR	T805	V810A	810	Missense	distal	5	no	13.074	13.083	EPSD	ICGC	10.658	Up-regulation
Atypical_PIKK_ATR_ATR_ST	O15360	FANCA	Q13535	ATR	S2	V6D	6	Missense	distal	4	no	10.686	10.472	EPSD	ICGC;COSMIC	10.658	Loss
Atypical_PIKK_ATR_ATR_ST	O15360	FANCA	Q13535	ATR	T381	E377D	377	Missense	distal	-4	no	13.731	13.549	EPSD	ICGC;COSMIC	10.658	Down-regulation
Atypical_PIKK_ATR_ATR_ST	O15360	FANCA	Q13535	ATR	T589	L587M	587	Missense	proximal	-2	no	10.940	10.606	EPSD	ICGC	10.658	Loss
Atypical_PIKK_ATR_ATR_ST	O15360	FANCA	Q13535	ATR	T589	H582P	582	Missense	distal	-7	no	10.940	10.963	EPSD	ICGC	10.658	Up-regulation
Atypical_PIKK_ATR_ATR_ST	O15360	FANCA	Q13535	ATR	S1449	H1453Y	1453	Missense	distal	4	no	16.222	17.078	PhosphoSitePlus	ICGC;COSMIC	10.658	Up-regulation
Atypical_PIKK_ATR_ATR_ST	O15360	FANCA	Q13535	ATR	S1449	D1447A	1447	Missense	proximal	-2	no	16.222	16.605	PhosphoSitePlus	ICGC;COSMIC	10.658	Up-regulation
Atypical_PIKK_ATR_ATR_ST	Q9UER7	DAXX	Q13535	ATR	T151	T151N	151	Missense	central	0	yes	11.622	0.000	EPSD	ICGC;COSMIC	10.658	Loss
Atypical_PIKK_ATR_ATR_ST	Q9UER7	DAXX	Q13535	ATR	T151	A149T	149	Missense	proximal	-2	no	11.622	11.149	EPSD	ICGC;COSMIC	10.658	Down-regulation
Atypical_PIKK_ATR_ATR_ST	Q9UER7	DAXX	Q13535	ATR	T151	N153S	153	Missense	proximal	2	no	11.622	11.309	EPSD	ICGC;COSMIC;GDSC;CCLE	10.658	Down-regulation
Atypical_PIKK_ATR_ATR_ST	Q9UER7	DAXX	Q13535	ATR	S152	T151N	151	Missense	proximal	-1	no	10.953	11.384	EPSD	ICGC;COSMIC	10.658	Up-regulation
Atypical_PIKK_ATR_ATR_ST	Q9UER7	DAXX	Q13535	ATR	S152	A149T	149	Missense	distal	-3	no	10.953	10.391	EPSD	ICGC;COSMIC	10.658	Loss
Atypical_PIKK_ATR_ATR_ST	Q9UER7	DAXX	Q13535	ATR	S152	N153S	153	Missense	proximal	1	no	10.953	9.252	EPSD	ICGC;COSMIC;GDSC;CCLE	10.658	Loss
Atypical_PIKK_ATR_ATR_ST	Q9UER7	DAXX	Q13535	ATR	S176	R182S	182	Missense	distal	6	no	13.958	14.354	EPSD	ICGC;COSMIC	10.658	Up-regulation
Atypical_PIKK_ATR_ATR_ST	Q9UER7	DAXX	Q13535	ATR	S176	G183V	183	Missense	distal	7	no	13.958	14.202	EPSD	ICGC;COSMIC	10.658	Up-regulation
Atypical_PIKK_ATR_ATR_ST	Q9UER7	DAXX	Q13535	ATR	S424	E417G	417	Missense	distal	-7	no	17.001	16.924	PhosphoSitePlus	ICGC	10.658	Down-regulation
Atypical_PIKK_ATR_ATR_ST	Q9UER7	DAXX	Q13535	ATR	S564	S561N	561	Missense	distal	-3	no	11.829	12.914	EPSD	ICGC;COSMIC	10.658	Up-regulation
Atypical_PIKK_ATR_ATR_ST	Q9UER7	DAXX	Q13535	ATR	S618	V617F	617	Missense	proximal	-1	no	11.540	11.522	EPSD	ICGC;COSMIC	10.658	Down-regulation
Atypical_PIKK_ATR_ATR_ST	Q9UER7	DAXX	Q13535	ATR	S618	V617I	617	Missense	proximal	-1	no	11.540	11.792	EPSD	ICGC;COSMIC	10.658	Up-regulation
Atypical_PIKK_ATR_ATR_ST	Q9UER7	DAXX	Q13535	ATR	T665	P670H	670	Missense	distal	5	no	10.695	10.688	EPSD	ICGC;COSMIC	10.658	Down-regulation
Atypical_PIKK_ATR_ATR_ST	Q9UER7	DAXX	Q13535	ATR	T665	S671P	671	Missense	distal	6	no	10.695	10.397	EPSD	ICGC;COSMIC;GDSC;CCLE	10.658	Loss
Atypical_PIKK_ATR_ATR_ST	Q9UER7	DAXX	Q13535	ATR	S688	T684M	684	Missense	distal	-4	no	11.222	11.089	EPSD	ICGC;COSMIC	10.658	Down-regulation
Atypical_PIKK_ATR_ATR_ST	Q03164	KMT2A	Q13535	ATR	S153	E146D	146	Missense	distal	-7	no	10.699	10.653	EPSD	ICGC	10.658	Loss
Atypical_PIKK_ATR_ATR_ST	Q03164	KMT2A	Q13535	ATR	S153	G150C	150	Missense	distal	-3	no	10.699	11.069	EPSD	ICGC;COSMIC	10.658	Up-regulation
Atypical_PIKK_ATR_ATR_ST	Q03164	KMT2A	Q13535	ATR	S252	I256N	256	Missense	distal	4	no	12.089	12.044	EPSD	ICGC;GDSC	10.658	Down-regulation
Atypical_PIKK_ATR_ATR_ST	Q03164	KMT2A	Q13535	ATR	S252	K246N	246	Missense	distal	-6	no	12.089	12.147	EPSD	ICGC;COSMIC	10.658	Up-regulation
Atypical_PIKK_ATR_ATR_ST	Q03164	KMT2A	Q13535	ATR	S279	K284T	284	Missense	distal	5	no	12.300	12.304	EPSD	ICGC;GDSC;CCLE	10.658	Up-regulation
Atypical_PIKK_ATR_ATR_ST	Q03164	KMT2A	Q13535	ATR	T314	S308P	308	Missense	distal	-6	no	10.640	10.685	EPSD	ICGC	10.658	Gain
Atypical_PIKK_ATR_ATR_ST	Q03164	KMT2A	Q13535	ATR	S470	S477F	477	Missense	distal	7	no	14.231	14.292	EPSD	ICGC;COSMIC	10.658	Up-regulation
Atypical_PIKK_ATR_ATR_ST	Q03164	KMT2A	Q13535	ATR	S481	S477F	477	Missense	distal	-4	no	12.718	12.434	EPSD	ICGC;COSMIC	10.658	Down-regulation
Atypical_PIKK_ATR_ATR_ST	Q03164	KMT2A	Q13535	ATR	S516	E522D	522	Missense	distal	6	no	16.341	16.067	PhosphoSitePlus	ICGC;COSMIC	10.658	Down-regulation
Atypical_PIKK_ATR_ATR_ST	Q03164	KMT2A	Q13535	ATR	S516	P514S	514	Missense	proximal	-2	no	16.341	16.290	PhosphoSitePlus	ICGC;COSMIC	10.658	Down-regulation
Atypical_PIKK_ATR_ATR_ST	Q03164	KMT2A	Q13535	ATR	T840	W838C	838	Missense	proximal	-2	no	10.579	10.703	EPSD	ICGC	10.658	Gain
Atypical_PIKK_ATR_ATR_ST	Q03164	KMT2A	Q13535	ATR	S843	W838C	838	Missense	distal	-5	no	15.502	15.479	EPSD	ICGC	10.658	Down-regulation
Atypical_PIKK_ATR_ATR_ST	Q03164	KMT2A	Q13535	ATR	S843	G848W	848	Missense	distal	5	no	15.502	15.508	EPSD	ICGC;COSMIC	10.658	Up-regulation
Atypical_PIKK_ATR_ATR_ST	Q03164	KMT2A	Q13535	ATR	S1107	I1104V	1104	Missense	distal	-3	no	14.530	14.946	EPSD	ICGC;COSMIC	10.658	Up-regulation
Atypical_PIKK_ATR_ATR_ST	Q03164	KMT2A	Q13535	ATR	S1107	K1103N	1103	Missense	distal	-4	no	14.530	14.149	EPSD	ICGC;COSMIC	10.658	Down-regulation
Atypical_PIKK_ATR_ATR_ST	Q03164	KMT2A	Q13535	ATR	S1241	S1241I	1241	Missense	central	0	yes	13.064	0.000	EPSD	ICGC;COSMIC	10.658	Loss
Atypical_PIKK_ATR_ATR_ST	Q03164	KMT2A	Q13535	ATR	S1241	P1246T	1246	Missense	distal	5	no	13.064	13.061	EPSD	ICGC;COSMIC	10.658	Down-regulation
Atypical_PIKK_ATR_ATR_ST	Q03164	KMT2A	Q13535	ATR	S1299	P1306L	1306	Missense	distal	7	no	15.557	15.555	EPSD	ICGC;COSMIC	10.658	Down-regulation
Atypical_PIKK_ATR_ATR_ST	Q03164	KMT2A	Q13535	ATR	S1299	K1296N	1296	Missense	distal	-3	no	15.557	16.717	EPSD	ICGC	10.658	Up-regulation
Atypical_PIKK_ATR_ATR_ST	Q03164	KMT2A	Q13535	ATR	T1382	S1384Y	1384	Missense	proximal	2	no	11.561	9.281	EPSD	ICGC;COSMIC	10.658	Loss
Atypical_PIKK_ATR_ATR_ST	Q03164	KMT2A	Q13535	ATR	T1695	P1689H	1689	Missense	distal	-6	no	11.783	11.826	EPSD	ICGC;COSMIC	10.658	Up-regulation
Atypical_PIKK_ATR_ATR_ST	Q03164	KMT2A	Q13535	ATR	S2118	D2123N	2123	Missense	distal	5	no	11.870	11.866	EPSD	ICGC;COSMIC	10.658	Down-regulation
Atypical_PIKK_ATR_ATR_ST	Q03164	KMT2A	Q13535	ATR	S2128	P2126L	2126	Missense	proximal	-2	no	15.525	16.176	EPSD	ICGC;COSMIC	10.658	Up-regulation
Atypical_PIKK_ATR_ATR_ST	Q03164	KMT2A	Q13535	ATR	S2128	D2123N	2123	Missense	distal	-5	no	15.525	15.498	EPSD	ICGC;COSMIC	10.658	Down-regulation
Atypical_PIKK_ATR_ATR_ST	Q03164	KMT2A	Q13535	ATR	S2128	C2134F	2134	Missense	distal	6	no	15.525	15.550	EPSD	ICGC	10.658	Up-regulation
Atypical_PIKK_ATR_ATR_ST	Q03164	KMT2A	Q13535	ATR	T2153	R2160Q	2160	Missense	distal	7	no	11.254	11.052	EPSD	ICGC;COSMIC	10.658	Down-regulation
Atypical_PIKK_ATR_ATR_ST	Q03164	KMT2A	Q13535	ATR	S2184	P2181H	2181	Missense	distal	-3	no	11.859	11.751	EPSD	ICGC;COSMIC	10.658	Down-regulation
Atypical_PIKK_ATR_ATR_ST	Q03164	KMT2A	Q13535	ATR	S2391	T2397I	2397	Missense	distal	6	no	10.968	10.742	EPSD	ICGC;COSMIC	10.658	Down-regulation
Atypical_PIKK_ATR_ATR_ST	Q03164	KMT2A	Q13535	ATR	S2391	D2396Y	2396	Missense	distal	5	no	10.968	10.980	EPSD	ICGC;COSMIC	10.658	Up-regulation
Atypical_PIKK_ATR_ATR_ST	Q03164	KMT2A	Q13535	ATR	S2392	T2397I	2397	Missense	distal	5	no	11.195	11.199	EPSD	ICGC;COSMIC	10.658	Up-regulation
Atypical_PIKK_ATR_ATR_ST	Q03164	KMT2A	Q13535	ATR	S2392	D2396Y	2396	Missense	distal	4	no	11.195	11.702	EPSD	ICGC;COSMIC	10.658	Up-regulation
Atypical_PIKK_ATR_ATR_ST	Q03164	KMT2A	Q13535	ATR	S2493	L2492V	2492	Missense	proximal	-1	no	12.863	12.647	EPSD	ICGC;COSMIC	10.658	Down-regulation
Atypical_PIKK_ATR_ATR_ST	Q03164	KMT2A	Q13535	ATR	S2493	S2493F	2493	Missense	central	0	yes	12.863	0.000	EPSD	ICGC;COSMIC	10.658	Loss
Atypical_PIKK_ATR_ATR_ST	Q03164	KMT2A	Q13535	ATR	S2859	T2857N	2857	Missense	proximal	-2	no	10.897	11.444	EPSD	ICGC	10.658	Up-regulation
Atypical_PIKK_ATR_ATR_ST	Q03164	KMT2A	Q13535	ATR	S2866	S2869L	2869	Missense	distal	3	no	13.147	12.480	EPSD	ICGC;COSMIC	10.658	Down-regulation
Atypical_PIKK_ATR_ATR_ST	Q02952	AKAP12	Q13535	ATR	S11	E8K	8	Missense	distal	-3	no	10.777	10.502	EPSD	ICGC;CCLE	10.658	Loss
Atypical_PIKK_ATR_ATR_ST	Q02952	AKAP12	Q13535	ATR	T21	P25S	25	Missense	distal	4	no	13.424	13.337	EPSD	ICGC;COSMIC	10.658	Down-regulation
Atypical_PIKK_ATR_ATR_ST	Q02952	AKAP12	Q13535	ATR	S227	K228N	228	Missense	proximal	1	no	6.098	12.788	EPSD	ICGC;COSMIC	10.658	Gain
Atypical_PIKK_ATR_ATR_ST	Q02952	AKAP12	Q13535	ATR	T289	S294Y	294	Missense	distal	5	no	11.455	11.476	EPSD	ICGC;COSMIC	10.658	Up-regulation
Atypical_PIKK_ATR_ATR_ST	Q02952	AKAP12	Q13535	ATR	S505	E507K	507	Missense	proximal	2	no	15.459	14.510	EPSD	ICGC;COSMIC	10.658	Down-regulation
Atypical_PIKK_ATR_ATR_ST	Q02952	AKAP12	Q13535	ATR	T521	S522L	522	Missense	proximal	1	no	11.065	11.609	EPSD	ICGC;COSMIC	10.658	Up-regulation
Atypical_PIKK_ATR_ATR_ST	Q02952	AKAP12	Q13535	ATR	T1039	E1033Q	1033	Missense	distal	-6	no	14.575	14.593	EPSD	ICGC;COSMIC	10.658	Up-regulation
Atypical_PIKK_ATR_ATR_ST	Q02952	AKAP12	Q13535	ATR	T1039	T1039A	1039	Missense	central	0	yes	14.575	0.000	EPSD	ICGC	10.658	Loss
Atypical_PIKK_ATR_ATR_ST	Q02952	AKAP12	Q13535	ATR	S1149	E1155D	1155	Missense	distal	6	no	14.427	14.153	EPSD	ICGC;COSMIC	10.658	Down-regulation
Atypical_PIKK_ATR_ATR_ST	Q9Y253	POLH	Q13535	ATR	T408	I403M	403	Missense	distal	-5	no	11.581	11.275	EPSD	ICGC;COSMIC	10.658	Down-regulation
Atypical_PIKK_ATR_ATR_ST	Q9Y253	POLH	Q13535	ATR	S551	S558F	558	Missense	distal	7	no	11.330	11.391	EPSD	ICGC	10.658	Up-regulation
Atypical_PIKK_ATR_ATR_ST	Q9Y253	POLH	Q13535	ATR	S551	S548L	548	Missense	distal	-3	no	11.330	11.901	EPSD	ICGC	10.658	Up-regulation
Atypical_PIKK_ATR_ATR_ST	Q9Y253	POLH	Q13535	ATR	S551	N546K	546	Missense	distal	-5	no	11.330	11.184	EPSD	ICGC	10.658	Down-regulation
Atypical_PIKK_ATR_ATR_ST	Q9Y253	POLH	Q13535	ATR	S601	M595V	595	Missense	distal	-6	no	13.889	13.901	PhosphoSitePlus	ICGC;COSMIC	10.658	Up-regulation
Atypical_PIKK_ATR_ATR_ST	Q9Y253	POLH	Q13535	ATR	T617	S612C	612	Missense	distal	-5	no	13.983	14.172	EPSD	ICGC	10.658	Up-regulation
Atypical_PIKK_ATR_ATR_ST	Q7Z6Z7	HUWE1	Q13535	ATR	T340	S345G	345	Missense	distal	5	no	11.337	11.343	EPSD	ICGC;COSMIC	10.658	Up-regulation
Atypical_PIKK_ATR_ATR_ST	Q7Z6Z7	HUWE1	Q13535	ATR	S525	D521E	521	Missense	distal	-4	no	11.995	12.177	EPSD	ICGC	10.658	Up-regulation
Atypical_PIKK_ATR_ATR_ST	Q7Z6Z7	HUWE1	Q13535	ATR	S636	P641Q	641	Missense	distal	5	no	11.656	11.646	EPSD	ICGC	10.658	Down-regulation
Atypical_PIKK_ATR_ATR_ST	Q7Z6Z7	HUWE1	Q13535	ATR	S636	R629C	629	Missense	distal	-7	no	11.656	11.478	EPSD	ICGC;COSMIC	10.658	Down-regulation
Atypical_PIKK_ATR_ATR_ST	Q7Z6Z7	HUWE1	Q13535	ATR	S649	R645K	645	Missense	distal	-4	no	10.619	11.521	EPSD	ICGC;COSMIC	10.658	Gain
Atypical_PIKK_ATR_ATR_ST	Q7Z6Z7	HUWE1	Q13535	ATR	S718	P714H	714	Missense	distal	-4	no	11.153	10.531	EPSD	ICGC	10.658	Loss
Atypical_PIKK_ATR_ATR_ST	Q7Z6Z7	HUWE1	Q13535	ATR	S740	T744I	744	Missense	distal	4	no	11.206	11.838	EPSD	ICGC	10.658	Up-regulation
Atypical_PIKK_ATR_ATR_ST	Q7Z6Z7	HUWE1	Q13535	ATR	T744	T744I	744	Missense	central	0	yes	13.605	0.000	EPSD	ICGC	10.658	Loss
Atypical_PIKK_ATR_ATR_ST	Q7Z6Z7	HUWE1	Q13535	ATR	S864	P865T	865	Missense	proximal	1	no	11.829	7.178	EPSD	ICGC;COSMIC	10.658	Loss
Atypical_PIKK_ATR_ATR_ST	Q7Z6Z7	HUWE1	Q13535	ATR	S927	Q928K	928	Missense	proximal	1	no	14.559	3.593	EPSD	ICGC;COSMIC	10.658	Loss
Atypical_PIKK_ATR_ATR_ST	Q7Z6Z7	HUWE1	Q13535	ATR	S990	G986A	986	Missense	distal	-4	no	10.548	11.586	EPSD	ICGC;COSMIC	10.658	Gain
Atypical_PIKK_ATR_ATR_ST	Q7Z6Z7	HUWE1	Q13535	ATR	T1005	A1003S	1003	Missense	proximal	-2	no	15.012	14.236	EPSD	ICGC;COSMIC	10.658	Down-regulation
Atypical_PIKK_ATR_ATR_ST	Q7Z6Z7	HUWE1	Q13535	ATR	T1005	L1008F	1008	Missense	distal	3	no	15.012	14.648	EPSD	ICGC	10.658	Down-regulation
Atypical_PIKK_ATR_ATR_ST	Q7Z6Z7	HUWE1	Q13535	ATR	S1030	P1027H	1027	Missense	distal	-3	no	11.312	11.204	EPSD	ICGC;COSMIC	10.658	Down-regulation
Atypical_PIKK_ATR_ATR_ST	Q7Z6Z7	HUWE1	Q13535	ATR	S1030	D1031E	1031	Missense	proximal	1	no	11.312	10.806	EPSD	ICGC	10.658	Down-regulation
Atypical_PIKK_ATR_ATR_ST	Q7Z6Z7	HUWE1	Q13535	ATR	S1175	A1173D	1173	Missense	proximal	-2	no	12.465	12.082	EPSD	ICGC	10.658	Down-regulation
Atypical_PIKK_ATR_ATR_ST	Q7Z6Z7	HUWE1	Q13535	ATR	S1175	P1181H	1181	Missense	distal	6	no	12.465	12.441	EPSD	ICGC;COSMIC	10.658	Down-regulation
Atypical_PIKK_ATR_ATR_ST	Q7Z6Z7	HUWE1	Q13535	ATR	S1218	L1222M	1222	Missense	distal	4	no	11.806	11.124	EPSD	ICGC	10.658	Down-regulation
Atypical_PIKK_ATR_ATR_ST	Q7Z6Z7	HUWE1	Q13535	ATR	S1218	P1223T	1223	Missense	distal	5	no	11.806	11.803	EPSD	ICGC	10.658	Down-regulation
Atypical_PIKK_ATR_ATR_ST	Q7Z6Z7	HUWE1	Q13535	ATR	S1218	P1212H	1212	Missense	distal	-6	no	11.806	11.849	EPSD	ICGC;COSMIC	10.658	Up-regulation
Atypical_PIKK_ATR_ATR_ST	Q7Z6Z7	HUWE1	Q13535	ATR	T1354	H1355N	1355	Missense	proximal	1	no	-2.197	11.045	EPSD	ICGC;COSMIC	10.658	Gain
Atypical_PIKK_ATR_ATR_ST	Q7Z6Z7	HUWE1	Q13535	ATR	S1736	E1734G	1734	Missense	proximal	-2	no	11.131	11.148	EPSD	ICGC;COSMIC	10.658	Up-regulation
Atypical_PIKK_ATR_ATR_ST	Q7Z6Z7	HUWE1	Q13535	ATR	S1736	E1738D	1738	Missense	proximal	2	no	11.131	9.455	EPSD	ICGC;COSMIC	10.658	Loss
Atypical_PIKK_ATR_ATR_ST	Q7Z6Z7	HUWE1	Q13535	ATR	T2003	R1996C	1996	Missense	distal	-7	no	13.917	13.739	EPSD	ICGC;COSMIC	10.658	Down-regulation
Atypical_PIKK_ATR_ATR_ST	Q7Z6Z7	HUWE1	Q13535	ATR	S2011	Q2012K	2012	Missense	proximal	1	no	13.088	2.121	EPSD	ICGC	10.658	Loss
Atypical_PIKK_ATR_ATR_ST	Q7Z6Z7	HUWE1	Q13535	ATR	S2275	E2276Q	2276	Missense	proximal	1	no	8.569	14.490	EPSD	ICGC;COSMIC	10.658	Gain
Atypical_PIKK_ATR_ATR_ST	Q7Z6Z7	HUWE1	Q13535	ATR	S2339	Q2340K	2340	Missense	proximal	1	no	15.536	4.570	EPSD	ICGC;COSMIC	10.658	Loss
Atypical_PIKK_ATR_ATR_ST	Q7Z6Z7	HUWE1	Q13535	ATR	S2339	Q2343H	2343	Missense	distal	4	no	15.536	15.248	EPSD	ICGC;COSMIC	10.658	Down-regulation
Atypical_PIKK_ATR_ATR_ST	Q7Z6Z7	HUWE1	Q13535	ATR	S2339	G2332W	2332	Missense	distal	-7	no	15.536	15.478	EPSD	ICGC;COSMIC	10.658	Down-regulation
Atypical_PIKK_ATR_ATR_ST	Q7Z6Z7	HUWE1	Q13535	ATR	S2391	A2393S	2393	Missense	proximal	2	no	16.807	16.659	PhosphoSitePlus	ICGC	10.658	Down-regulation
Atypical_PIKK_ATR_ATR_ST	Q7Z6Z7	HUWE1	Q13535	ATR	S2391	Q2397R	2397	Missense	distal	6	no	16.807	16.538	PhosphoSitePlus	ICGC;COSMIC	10.658	Down-regulation
Atypical_PIKK_ATR_ATR_ST	Q7Z6Z7	HUWE1	Q13535	ATR	S2508	A2502T	2502	Missense	distal	-6	no	11.458	11.436	EPSD	ICGC;COSMIC	10.658	Down-regulation
Atypical_PIKK_ATR_ATR_ST	Q7Z6Z7	HUWE1	Q13535	ATR	T2540	T2537A	2537	Missense	distal	-3	no	14.630	15.192	EPSD	ICGC;COSMIC	10.658	Up-regulation
Atypical_PIKK_ATR_ATR_ST	Q7Z6Z7	HUWE1	Q13535	ATR	T2540	L2539I	2539	Missense	proximal	-1	no	14.630	14.667	EPSD	ICGC	10.658	Up-regulation
Atypical_PIKK_ATR_ATR_ST	Q7Z6Z7	HUWE1	Q13535	ATR	S2546	L2539I	2539	Missense	distal	-7	no	12.203	12.251	EPSD	ICGC	10.658	Up-regulation
Atypical_PIKK_ATR_ATR_ST	Q7Z6Z7	HUWE1	Q13535	ATR	S2636	A2638V	2638	Missense	proximal	2	no	11.823	12.312	EPSD	ICGC;COSMIC	10.658	Up-regulation
Atypical_PIKK_ATR_ATR_ST	Q7Z6Z7	HUWE1	Q13535	ATR	S2636	A2638E	2638	Missense	proximal	2	no	11.823	12.744	EPSD	ICGC	10.658	Up-regulation
Atypical_PIKK_ATR_ATR_ST	Q7Z6Z7	HUWE1	Q13535	ATR	T2640	A2638V	2638	Missense	proximal	-2	no	14.433	13.914	EPSD	ICGC;COSMIC	10.658	Down-regulation
Atypical_PIKK_ATR_ATR_ST	Q7Z6Z7	HUWE1	Q13535	ATR	T2640	A2638E	2638	Missense	proximal	-2	no	14.433	13.954	EPSD	ICGC	10.658	Down-regulation
Atypical_PIKK_ATR_ATR_ST	Q7Z6Z7	HUWE1	Q13535	ATR	T2640	P2645H	2645	Missense	distal	5	no	14.433	14.427	EPSD	ICGC;COSMIC	10.658	Down-regulation
Atypical_PIKK_ATR_ATR_ST	Q7Z6Z7	HUWE1	Q13535	ATR	S2735	G2737V	2737	Missense	proximal	2	no	12.265	11.963	EPSD	ICGC;COSMIC	10.658	Down-regulation
Atypical_PIKK_ATR_ATR_ST	Q7Z6Z7	HUWE1	Q13535	ATR	S2735	G2737W	2737	Missense	proximal	2	no	12.265	10.700	EPSD	ICGC;COSMIC	10.658	Down-regulation
Atypical_PIKK_ATR_ATR_ST	Q7Z6Z7	HUWE1	Q13535	ATR	T2821	E2819Q	2819	Missense	proximal	-2	no	15.256	15.291	EPSD	ICGC;COSMIC	10.658	Up-regulation
Atypical_PIKK_ATR_ATR_ST	Q7Z6Z7	HUWE1	Q13535	ATR	T2821	T2820K	2820	Missense	proximal	-1	no	15.256	15.102	EPSD	ICGC;COSMIC	10.658	Down-regulation
Atypical_PIKK_ATR_ATR_ST	Q7Z6Z7	HUWE1	Q13535	ATR	S2850	T2846K	2846	Missense	distal	-4	no	13.939	14.630	EPSD	ICGC;COSMIC	10.658	Up-regulation
Atypical_PIKK_ATR_ATR_ST	Q7Z6Z7	HUWE1	Q13535	ATR	S2888	T2889N	2889	Missense	proximal	1	no	7.217	12.460	EPSD	ICGC;COSMIC	10.658	Gain
Atypical_PIKK_ATR_ATR_ST	Q7Z6Z7	HUWE1	Q13535	ATR	T2889	T2889N	2889	Missense	central	0	yes	11.412	0.000	EPSD	ICGC;COSMIC	10.658	Loss
Atypical_PIKK_ATR_ATR_ST	Q7Z6Z7	HUWE1	Q13535	ATR	T2889	P2895Q	2895	Missense	distal	6	no	11.412	11.582	EPSD	ICGC;COSMIC	10.658	Up-regulation
Atypical_PIKK_ATR_ATR_ST	Q7Z6Z7	HUWE1	Q13535	ATR	T2889	P2883L	2883	Missense	distal	-6	no	11.412	11.477	EPSD	ICGC;COSMIC	10.658	Up-regulation
Atypical_PIKK_ATR_ATR_ST	Q7Z6Z7	HUWE1	Q13535	ATR	S2904	A2911V	2911	Missense	distal	7	no	10.709	10.849	EPSD	ICGC;COSMIC	10.658	Up-regulation
Atypical_PIKK_ATR_ATR_ST	Q7Z6Z7	HUWE1	Q13535	ATR	S2904	R2903M	2903	Missense	proximal	-1	no	10.709	10.752	EPSD	ICGC;COSMIC	10.658	Up-regulation
Atypical_PIKK_ATR_ATR_ST	Q7Z6Z7	HUWE1	Q13535	ATR	S2922	T2928N	2928	Missense	distal	6	no	10.847	11.008	EPSD	ICGC	10.658	Up-regulation
Atypical_PIKK_ATR_ATR_ST	Q7Z6Z7	HUWE1	Q13535	ATR	S2927	T2928N	2928	Missense	proximal	1	no	5.840	11.083	EPSD	ICGC	10.658	Gain
Atypical_PIKK_ATR_ATR_ST	Q7Z6Z7	HUWE1	Q13535	ATR	S2940	D2939H	2939	Missense	proximal	-1	no	11.278	11.112	EPSD	ICGC;COSMIC	10.658	Down-regulation
Atypical_PIKK_ATR_ATR_ST	Q7Z6Z7	HUWE1	Q13535	ATR	S2940	P2947T	2947	Missense	distal	7	no	11.278	11.286	EPSD	ICGC;COSMIC	10.658	Up-regulation
Atypical_PIKK_ATR_ATR_ST	Q7Z6Z7	HUWE1	Q13535	ATR	S2940	P2947L	2947	Missense	distal	7	no	11.278	11.276	EPSD	ICGC;COSMIC;GDSC;CCLE	10.658	Down-regulation
Atypical_PIKK_ATR_ATR_ST	Q7Z6Z7	HUWE1	Q13535	ATR	S2953	P2958L	2958	Missense	distal	5	no	12.169	12.164	EPSD	ICGC;COSMIC	10.658	Down-regulation
Atypical_PIKK_ATR_ATR_ST	Q7Z6Z7	HUWE1	Q13535	ATR	S2953	P2947T	2947	Missense	distal	-6	no	12.169	12.209	EPSD	ICGC;COSMIC	10.658	Up-regulation
Atypical_PIKK_ATR_ATR_ST	Q7Z6Z7	HUWE1	Q13535	ATR	S2953	P2947L	2947	Missense	distal	-6	no	12.169	12.233	EPSD	ICGC;COSMIC;GDSC;CCLE	10.658	Up-regulation
Atypical_PIKK_ATR_ATR_ST	Q7Z6Z7	HUWE1	Q13535	ATR	S2963	P2958L	2958	Missense	distal	-5	no	10.956	11.109	EPSD	ICGC;COSMIC	10.658	Up-regulation
Atypical_PIKK_ATR_ATR_ST	Q7Z6Z7	HUWE1	Q13535	ATR	S2963	S2963C	2963	Missense	central	0	yes	10.956	0.000	EPSD	ICGC;COSMIC	10.658	Loss
Atypical_PIKK_ATR_ATR_ST	Q7Z6Z7	HUWE1	Q13535	ATR	S3018	T3015N	3015	Missense	distal	-3	no	11.641	12.447	EPSD	ICGC	10.658	Up-regulation
Atypical_PIKK_ATR_ATR_ST	Q7Z6Z7	HUWE1	Q13535	ATR	S3018	P3012T	3012	Missense	distal	-6	no	11.641	11.681	EPSD	ICGC;COSMIC	10.658	Up-regulation
Atypical_PIKK_ATR_ATR_ST	Q7Z6Z7	HUWE1	Q13535	ATR	S3377	Q3378R	3378	Missense	proximal	1	no	12.196	5.200	EPSD	ICGC	10.658	Loss
Atypical_PIKK_ATR_ATR_ST	Q7Z6Z7	HUWE1	Q13535	ATR	S3377	S3381C	3381	Missense	distal	4	no	12.196	12.885	EPSD	ICGC;COSMIC	10.658	Up-regulation
Atypical_PIKK_ATR_ATR_ST	Q7Z6Z7	HUWE1	Q13535	ATR	S3377	A3371T	3371	Missense	distal	-6	no	12.196	12.174	EPSD	ICGC;COSMIC	10.658	Down-regulation
Atypical_PIKK_ATR_ATR_ST	Q7Z6Z7	HUWE1	Q13535	ATR	S3695	R3698Q	3698	Missense	distal	3	no	13.817	13.822	EPSD	ICGC;COSMIC	10.658	Up-regulation
Atypical_PIKK_ATR_ATR_ST	Q7Z6Z7	HUWE1	Q13535	ATR	S3695	P3699S	3699	Missense	distal	4	no	13.817	13.730	EPSD	ICGC;COSMIC	10.658	Down-regulation
Atypical_PIKK_ATR_ATR_ST	Q7Z6Z7	HUWE1	Q13535	ATR	S3794	E3795Q	3795	Missense	proximal	1	no	9.208	15.129	EPSD	ICGC;COSMIC	10.658	Gain
Atypical_PIKK_ATR_ATR_ST	Q7Z6Z7	HUWE1	Q13535	ATR	S3797	E3795Q	3795	Missense	proximal	-2	no	13.897	13.932	EPSD	ICGC;COSMIC	10.658	Up-regulation
Atypical_PIKK_ATR_ATR_ST	Q7Z6Z7	HUWE1	Q13535	ATR	S3797	R3804Q	3804	Missense	distal	7	no	13.897	13.695	EPSD	ICGC;COSMIC	10.658	Down-regulation
Atypical_PIKK_ATR_ATR_ST	Q7Z6Z7	HUWE1	Q13535	ATR	T4083	L4080F	4080	Missense	distal	-3	no	11.409	11.697	EPSD	ICGC;COSMIC	10.658	Up-regulation
Atypical_PIKK_ATR_ATR_ST	Q7Z6Z7	HUWE1	Q13535	ATR	T4083	M4077V	4077	Missense	distal	-6	no	11.409	11.422	EPSD	ICGC;COSMIC	10.658	Up-regulation
Atypical_PIKK_ATR_ATR_ST	Q7Z6Z7	HUWE1	Q13535	ATR	T4083	P4085L	4085	Missense	proximal	2	no	11.409	10.128	EPSD	ICGC	10.658	Loss
Atypical_PIKK_ATR_ATR_ST	Q9NZN8	CNOT2	Q13535	ATR	S45	H38L	38	Missense	distal	-7	no	12.676	12.506	EPSD	ICGC;COSMIC	10.658	Down-regulation
Atypical_PIKK_ATR_ATR_ST	Q9NZN8	CNOT2	Q13535	ATR	S45	M42I	42	Missense	distal	-3	no	12.676	12.684	EPSD	ICGC	10.658	Up-regulation
Atypical_PIKK_ATR_ATR_ST	Q9NZN8	CNOT2	Q13535	ATR	S45	H38R	38	Missense	distal	-7	no	12.676	12.624	EPSD	ICGC;COSMIC	10.658	Down-regulation
Atypical_PIKK_ATR_ATR_ST	Q9NZN8	CNOT2	Q13535	ATR	S45	S45I	45	Missense	central	0	yes	12.676	0.000	EPSD	ICGC	10.658	Loss
Atypical_PIKK_ATR_ATR_ST	Q9NZN8	CNOT2	Q13535	ATR	S101	R98H	98	Missense	distal	-3	no	18.222	17.854	PhosphoSitePlus	ICGC;COSMIC	10.658	Down-regulation
Atypical_PIKK_ATR_ATR_ST	Q9NZN8	CNOT2	Q13535	ATR	S101	Q105K	105	Missense	distal	4	no	18.222	18.205	PhosphoSitePlus	ICGC;COSMIC	10.658	Down-regulation
Atypical_PIKK_ATR_ATR_ST	Q9NZN8	CNOT2	Q13535	ATR	S143	M140I	140	Missense	distal	-3	no	12.536	12.545	EPSD	ICGC;COSMIC	10.658	Up-regulation
Atypical_PIKK_ATR_ATR_ST	Q9NZN8	CNOT2	Q13535	ATR	S143	R137W	137	Missense	distal	-6	no	12.536	12.547	EPSD	ICGC;COSMIC	10.658	Up-regulation
Atypical_PIKK_ATR_ATR_ST	Q9NZN8	CNOT2	Q13535	ATR	S143	Q147R	147	Missense	distal	4	no	12.536	12.702	EPSD	ICGC	10.658	Up-regulation
Atypical_PIKK_ATR_ATR_ST	Q9NZN8	CNOT2	Q13535	ATR	S143	G150K	150	Missense	distal	7	no	12.536	12.681	EPSD	ICGC	10.658	Up-regulation
Atypical_PIKK_ATR_ATR_ST	Q9NZN8	CNOT2	Q13535	ATR	S143	P136H	136	Missense	distal	-7	no	12.536	12.513	EPSD	ICGC;COSMIC	10.658	Down-regulation
Atypical_PIKK_ATR_ATR_ST	Q9NZN8	CNOT2	Q13535	ATR	S143	G148E	148	Missense	distal	5	no	12.536	12.525	EPSD	ICGC;COSMIC	10.658	Down-regulation
Atypical_PIKK_ATR_ATR_ST	Q9NZN8	CNOT2	Q13535	ATR	S165	S169I	169	Missense	distal	4	no	10.527	11.210	EPSD	ICGC	10.658	Gain
Atypical_PIKK_ATR_ATR_ST	Q9NZN8	CNOT2	Q13535	ATR	S170	I173M	173	Missense	distal	3	no	11.218	10.518	EPSD	ICGC;COSMIC	10.658	Loss
Atypical_PIKK_ATR_ATR_ST	Q9NZN8	CNOT2	Q13535	ATR	S170	C175F	175	Missense	distal	5	no	11.218	11.204	EPSD	ICGC	10.658	Down-regulation
Atypical_PIKK_ATR_ATR_ST	Q9NZN8	CNOT2	Q13535	ATR	S170	S169I	169	Missense	proximal	-1	no	11.218	11.490	EPSD	ICGC	10.658	Up-regulation
Atypical_PIKK_ATR_ATR_ST	Q9NZN8	CNOT2	Q13535	ATR	S190	G195E	195	Missense	distal	5	no	12.653	12.642	EPSD	ICGC;COSMIC	10.658	Down-regulation
Atypical_PIKK_ATR_ATR_ST	Q9NZN8	CNOT2	Q13535	ATR	S270	S270F	270	Missense	central	0	yes	13.291	0.000	EPSD	ICGC;COSMIC	10.658	Loss
Atypical_PIKK_ATR_ATR_ST	Q9NZN8	CNOT2	Q13535	ATR	S305	N303S	303	Missense	proximal	-2	no	10.856	10.007	EPSD	ICGC;COSMIC	10.658	Loss
Atypical_PIKK_ATR_ATR_ST	Q9NZN8	CNOT2	Q13535	ATR	S305	K307N	307	Missense	proximal	2	no	10.856	11.050	EPSD	ICGC	10.658	Up-regulation
Atypical_PIKK_ATR_ATR_ST	Q9NZN8	CNOT2	Q13535	ATR	S305	G306A	306	Missense	proximal	1	no	10.856	9.073	EPSD	ICGC;COSMIC	10.658	Loss
Atypical_PIKK_ATR_ATR_ST	Q9NZN8	CNOT2	Q13535	ATR	S305	S298I	298	Missense	distal	-7	no	10.856	10.739	EPSD	ICGC;COSMIC	10.658	Down-regulation
Atypical_PIKK_ATR_ATR_ST	Q9UH99	SUN2	Q13535	ATR	S5	R10K	10	Missense	distal	5	no	14.154	14.147	EPSD	ICGC	10.658	Down-regulation
Atypical_PIKK_ATR_ATR_ST	Q9UH99	SUN2	Q13535	ATR	S5	R7H	7	Missense	proximal	2	no	14.154	13.922	EPSD	ICGC;COSMIC;CCLE	10.658	Down-regulation
Atypical_PIKK_ATR_ATR_ST	Q9UH99	SUN2	Q13535	ATR	S12	R10K	10	Missense	proximal	-2	no	14.831	14.817	PhosphoSitePlus	ICGC	10.658	Down-regulation
Atypical_PIKK_ATR_ATR_ST	Q9UH99	SUN2	Q13535	ATR	S12	S19R	19	Missense	distal	7	no	14.831	15.055	PhosphoSitePlus	ICGC	10.658	Up-regulation
Atypical_PIKK_ATR_ATR_ST	Q9UH99	SUN2	Q13535	ATR	S12	R7H	7	Missense	distal	-5	no	14.831	14.770	PhosphoSitePlus	ICGC;COSMIC;CCLE	10.658	Down-regulation
Atypical_PIKK_ATR_ATR_ST	Q9UH99	SUN2	Q13535	ATR	S19	S19R	19	Missense	central	0	yes	11.333	0.000	EPSD	ICGC	10.658	Loss
Atypical_PIKK_ATR_ATR_ST	Q9UH99	SUN2	Q13535	ATR	S19	S22R	22	Missense	distal	3	no	11.333	10.897	EPSD	ICGC	10.658	Down-regulation
Atypical_PIKK_ATR_ATR_ST	Q9UH99	SUN2	Q13535	ATR	S19	G23E	23	Missense	distal	4	no	11.333	10.322	EPSD	ICGC	10.658	Loss
Atypical_PIKK_ATR_ATR_ST	Q9UH99	SUN2	Q13535	ATR	S30	T33A	33	Missense	distal	3	no	15.351	15.039	EPSD	ICGC;COSMIC	10.658	Down-regulation
Atypical_PIKK_ATR_ATR_ST	Q9UH99	SUN2	Q13535	ATR	S30	S30G	30	Missense	central	0	yes	15.351	0.000	EPSD	ICGC;COSMIC	10.658	Loss
Atypical_PIKK_ATR_ATR_ST	Q9UH99	SUN2	Q13535	ATR	S30	G23E	23	Missense	distal	-7	no	15.351	15.429	EPSD	ICGC	10.658	Up-regulation
Atypical_PIKK_ATR_ATR_ST	Q9UH99	SUN2	Q13535	ATR	S85	L89R	89	Missense	distal	4	no	10.863	10.678	EPSD	ICGC	10.658	Down-regulation
Atypical_PIKK_ATR_ATR_ST	Q9UH99	SUN2	Q13535	ATR	S160	R161W	161	Missense	proximal	1	no	11.790	11.863	EPSD	ICGC;COSMIC	10.658	Up-regulation
Atypical_PIKK_ATR_ATR_ST	Q9UH99	SUN2	Q13535	ATR	S160	L166P	166	Missense	distal	6	no	11.790	11.718	EPSD	ICGC;COSMIC	10.658	Down-regulation
Atypical_PIKK_ATR_ATR_ST	Q9UH99	SUN2	Q13535	ATR	S160	R154W	154	Missense	distal	-6	no	11.790	11.802	EPSD	ICGC;COSMIC	10.658	Up-regulation
Atypical_PIKK_ATR_ATR_ST	Q9UH99	SUN2	Q13535	ATR	S282	R286H	286	Missense	distal	4	no	10.712	10.258	EPSD	ICGC;COSMIC	10.658	Loss
Atypical_PIKK_ATR_ATR_ST	Q9UH99	SUN2	Q13535	ATR	S381	F374L	374	Missense	distal	-7	no	13.945	13.888	EPSD	ICGC	10.658	Down-regulation
Atypical_PIKK_ATR_ATR_ST	Q9UH99	SUN2	Q13535	ATR	S381	S381F	381	Missense	central	0	yes	13.945	0.000	EPSD	ICGC;COSMIC	10.658	Loss
Atypical_PIKK_ATR_ATR_ST	Q9BUG6	ZSCAN5A	Q13535	ATR	T236	E230K	230	Missense	distal	-6	no	12.241	12.194	EPSD	ICGC;COSMIC	10.658	Down-regulation
Atypical_PIKK_ATR_ATR_ST	Q9BUG6	ZSCAN5A	Q13535	ATR	S308	S305F	305	Missense	distal	-3	no	12.844	13.703	EPSD	ICGC;COSMIC;GDSC;CCLE	10.658	Up-regulation
Atypical_PIKK_ATR_ATR_ST	Q9BUG6	ZSCAN5A	Q13535	ATR	S308	E311G	311	Missense	distal	3	no	12.844	12.665	EPSD	ICGC;COSMIC	10.658	Down-regulation
Atypical_PIKK_ATR_ATR_ST	Q9BUG6	ZSCAN5A	Q13535	ATR	S308	E315K	315	Missense	distal	7	no	12.844	12.993	EPSD	ICGC;COSMIC	10.658	Up-regulation
Atypical_PIKK_ATR_ATR_ST	Q8IZL8	PELP1	Q13535	ATR	S251	S245F	245	Missense	distal	-6	no	12.188	12.268	EPSD	ICGC	10.658	Up-regulation
Atypical_PIKK_ATR_ATR_ST	Q8IZL8	PELP1	Q13535	ATR	S991	P993L	993	Missense	proximal	2	no	11.673	10.391	EPSD	ICGC	10.658	Loss
Atypical_PIKK_ATR_ATR_ST	O94880	PHF14	Q13535	ATR	S39	G43C	43	Missense	distal	4	no	10.900	10.820	EPSD	ICGC;COSMIC	10.658	Down-regulation
Atypical_PIKK_ATR_ATR_ST	O94880	PHF14	Q13535	ATR	S59	E55K	55	Missense	distal	-4	no	12.400	11.989	EPSD	ICGC;COSMIC	10.658	Down-regulation
Atypical_PIKK_ATR_ATR_ST	O94880	PHF14	Q13535	ATR	T162	T169M	169	Missense	distal	7	no	11.150	10.973	EPSD	ICGC;COSMIC	10.658	Down-regulation
Atypical_PIKK_ATR_ATR_ST	O94880	PHF14	Q13535	ATR	S163	T169M	169	Missense	distal	6	no	11.998	11.705	EPSD	ICGC;COSMIC	10.658	Down-regulation
Atypical_PIKK_ATR_ATR_ST	O94880	PHF14	Q13535	ATR	T287	L293I	293	Missense	distal	6	no	11.825	11.777	EPSD	ICGC;COSMIC	10.658	Down-regulation
Atypical_PIKK_ATR_ATR_ST	O94880	PHF14	Q13535	ATR	T287	N288D	288	Missense	proximal	1	no	11.825	10.687	EPSD	ICGC	10.658	Down-regulation
Atypical_PIKK_ATR_ATR_ST	O94880	PHF14	Q13535	ATR	T287	S294F	294	Missense	distal	7	no	11.825	11.887	EPSD	ICGC;COSMIC	10.658	Up-regulation
Atypical_PIKK_ATR_ATR_ST	O94880	PHF14	Q13535	ATR	T292	N288D	288	Missense	distal	-4	no	10.322	10.931	EPSD	ICGC	10.658	Gain
Atypical_PIKK_ATR_ATR_ST	O94880	PHF14	Q13535	ATR	S294	L293I	293	Missense	proximal	-1	no	17.072	17.108	PhosphoSitePlus	ICGC;COSMIC	10.658	Up-regulation
Atypical_PIKK_ATR_ATR_ST	O94880	PHF14	Q13535	ATR	S294	N288D	288	Missense	distal	-6	no	17.072	17.069	PhosphoSitePlus	ICGC	10.658	Down-regulation
Atypical_PIKK_ATR_ATR_ST	O94880	PHF14	Q13535	ATR	S294	S298N	298	Missense	distal	4	no	17.072	17.709	PhosphoSitePlus	ICGC	10.658	Up-regulation
Atypical_PIKK_ATR_ATR_ST	O94880	PHF14	Q13535	ATR	S294	S294F	294	Missense	central	0	yes	17.072	0.000	PhosphoSitePlus	ICGC;COSMIC	10.658	Loss
Atypical_PIKK_ATR_ATR_ST	O94880	PHF14	Q13535	ATR	S302	S298N	298	Missense	distal	-4	no	11.437	11.659	EPSD	ICGC	10.658	Up-regulation
Atypical_PIKK_ATR_ATR_ST	O94880	PHF14	Q13535	ATR	S308	S313L	313	Missense	distal	5	no	11.856	11.863	EPSD	ICGC;COSMIC	10.658	Up-regulation
Atypical_PIKK_ATR_ATR_ST	O94880	PHF14	Q13535	ATR	S313	S313L	313	Missense	central	0	yes	13.131	0.000	EPSD	ICGC;COSMIC	10.658	Loss
Atypical_PIKK_ATR_ATR_ST	O94880	PHF14	Q13535	ATR	S530	P531S	531	Missense	proximal	1	no	12.401	11.291	EPSD	ICGC;COSMIC	10.658	Down-regulation
Atypical_PIKK_ATR_ATR_ST	O94880	PHF14	Q13535	ATR	S530	Q528H	528	Missense	proximal	-2	no	12.401	12.034	EPSD	ICGC;COSMIC	10.658	Down-regulation
Atypical_PIKK_ATR_ATR_ST	Q8N4S0	CCDC82	Q13535	ATR	S131	K128R	128	Missense	distal	-3	no	13.651	14.263	EPSD	ICGC	10.658	Up-regulation
Atypical_PIKK_ATR_ATR_ST	Q8N4S0	CCDC82	Q13535	ATR	S131	L130V	130	Missense	proximal	-1	no	13.651	13.435	EPSD	ICGC	10.658	Down-regulation
Atypical_PIKK_ATR_ATR_ST	Q8N4S0	CCDC82	Q13535	ATR	S131	D125N	125	Missense	distal	-6	no	13.651	13.654	EPSD	ICGC	10.658	Up-regulation
Atypical_PIKK_ATR_ATR_ST	Q8N4S0	CCDC82	Q13535	ATR	S154	D147E	147	Missense	distal	-7	no	16.298	16.344	PhosphoSitePlus	ICGC;COSMIC	10.658	Up-regulation
Atypical_PIKK_ATR_ATR_ST	Q8N4S0	CCDC82	Q13535	ATR	S154	N161K	161	Missense	distal	7	no	16.298	16.028	PhosphoSitePlus	ICGC	10.658	Down-regulation
Atypical_PIKK_ATR_ATR_ST	Q8N4S0	CCDC82	Q13535	ATR	S264	P270T	270	Missense	distal	6	no	10.519	10.769	EPSD	ICGC;COSMIC	10.658	Gain
Atypical_PIKK_ATR_ATR_ST	Q8N4S0	CCDC82	Q13535	ATR	S320	Q327R	327	Missense	distal	7	no	13.838	14.040	EPSD	ICGC;COSMIC	10.658	Up-regulation
Atypical_PIKK_ATR_ATR_ST	Q8IUQ4	SIAH1	Q13535	ATR	S19	P18L	18	Missense	proximal	-1	no	14.935	14.955	PhosphoSitePlus	ICGC;COSMIC	10.658	Up-regulation
Atypical_PIKK_ATR_ATR_ST	Q8IUQ4	SIAH1	Q13535	ATR	S19	C16Y	16	Missense	distal	-3	no	14.935	15.360	PhosphoSitePlus	ICGC	10.658	Up-regulation
Atypical_PIKK_ATR_ATR_ST	Q8IUQ4	SIAH1	Q13535	ATR	S19	P23T	23	Missense	distal	4	no	14.935	14.899	PhosphoSitePlus	ICGC	10.658	Down-regulation
Atypical_PIKK_ATR_ATR_ST	Q8IUQ4	SIAH1	Q13535	ATR	S19	A24S	24	Missense	distal	5	no	14.935	14.923	PhosphoSitePlus	ICGC;COSMIC	10.658	Down-regulation
Atypical_PIKK_ATR_ATR_ST	Q8IUQ4	SIAH1	Q13535	ATR	S19	Q20K	20	Missense	proximal	1	no	14.935	3.968	PhosphoSitePlus	ICGC;COSMIC	10.658	Loss
Atypical_PIKK_ATR_ATR_ST	Q01844	EWSR1	Q13535	ATR	S358	A362S	362	Missense	distal	4	no	11.651	11.349	EPSD	ICGC;COSMIC	10.658	Down-regulation
Atypical_PIKK_ATR_ATR_ST	Q14676	MDC1	Q13535	ATR	S20	R25M	25	Missense	distal	5	no	10.976	10.974	EPSD	ICGC	10.658	Down-regulation
Atypical_PIKK_ATR_ATR_ST	Q14676	MDC1	Q13535	ATR	S23	R25M	25	Missense	proximal	2	no	11.770	12.450	EPSD	ICGC	10.658	Up-regulation
Atypical_PIKK_ATR_ATR_ST	Q14676	MDC1	Q13535	ATR	S108	R114C	114	Missense	distal	6	no	10.591	10.804	EPSD	ICGC;COSMIC	10.658	Gain
Atypical_PIKK_ATR_ATR_ST	Q14676	MDC1	Q13535	ATR	S202	G207D	207	Missense	distal	5	no	11.539	11.543	EPSD	ICGC;COSMIC	10.658	Up-regulation
Atypical_PIKK_ATR_ATR_ST	Q14676	MDC1	Q13535	ATR	S218	L216V	216	Missense	proximal	-2	no	13.752	13.305	EPSD	ICGC;COSMIC	10.658	Down-regulation
Atypical_PIKK_ATR_ATR_ST	Q14676	MDC1	Q13535	ATR	S218	D219V	219	Missense	proximal	1	no	13.752	-0.529	EPSD	ICGC;COSMIC	10.658	Loss
Atypical_PIKK_ATR_ATR_ST	Q14676	MDC1	Q13535	ATR	S218	D219E	219	Missense	proximal	1	no	13.752	13.245	EPSD	ICGC;COSMIC	10.658	Down-regulation
Atypical_PIKK_ATR_ATR_ST	Q14676	MDC1	Q13535	ATR	S292	D298N	298	Missense	distal	6	no	14.708	15.011	EPSD	ICGC;COSMIC	10.658	Up-regulation
Atypical_PIKK_ATR_ATR_ST	Q14676	MDC1	Q13535	ATR	T301	D298N	298	Missense	distal	-3	no	13.462	13.754	EPSD	ICGC;COSMIC	10.658	Up-regulation
Atypical_PIKK_ATR_ATR_ST	Q14676	MDC1	Q13535	ATR	T341	I338M	338	Missense	distal	-3	no	10.689	10.681	EPSD	ICGC;COSMIC	10.658	Down-regulation
Atypical_PIKK_ATR_ATR_ST	Q14676	MDC1	Q13535	ATR	S372	E371K	371	Missense	proximal	-1	no	13.331	13.082	EPSD	ICGC;COSMIC	10.658	Down-regulation
Atypical_PIKK_ATR_ATR_ST	Q14676	MDC1	Q13535	ATR	S372	H368N	368	Missense	distal	-4	no	13.331	13.851	EPSD	ICGC;COSMIC	10.658	Up-regulation
Atypical_PIKK_ATR_ATR_ST	Q14676	MDC1	Q13535	ATR	S422	W427L	427	Missense	distal	5	no	14.280	14.276	EPSD	ICGC;COSMIC	10.658	Down-regulation
Atypical_PIKK_ATR_ATR_ST	Q14676	MDC1	Q13535	ATR	S445	D452G	452	Missense	distal	7	no	12.072	11.882	EPSD	ICGC	10.658	Down-regulation
Atypical_PIKK_ATR_ATR_ST	Q14676	MDC1	Q13535	ATR	S445	S445R	445	Missense	central	0	yes	12.072	0.000	EPSD	ICGC;COSMIC	10.658	Loss
Atypical_PIKK_ATR_ATR_ST	Q14676	MDC1	Q13535	ATR	S598	G604R	604	Missense	distal	6	no	15.541	15.387	EPSD	ICGC;COSMIC	10.658	Down-regulation
Atypical_PIKK_ATR_ATR_ST	Q14676	MDC1	Q13535	ATR	T659	G665E	665	Missense	distal	6	no	11.187	11.515	EPSD	ICGC;COSMIC	10.658	Up-regulation
Atypical_PIKK_ATR_ATR_ST	Q14676	MDC1	Q13535	ATR	T659	A666P	666	Missense	distal	7	no	11.187	11.280	EPSD	ICGC;COSMIC	10.658	Up-regulation
Atypical_PIKK_ATR_ATR_ST	Q14676	MDC1	Q13535	ATR	T659	L655I	655	Missense	distal	-4	no	11.187	10.720	EPSD	ICGC	10.658	Down-regulation
Atypical_PIKK_ATR_ATR_ST	Q14676	MDC1	Q13535	ATR	T725	P727L	727	Missense	proximal	2	no	10.959	9.678	EPSD	ICGC;COSMIC	10.658	Loss
Atypical_PIKK_ATR_ATR_ST	Q14676	MDC1	Q13535	ATR	T752	W747L	747	Missense	distal	-5	no	12.821	12.791	EPSD	ICGC;COSMIC	10.658	Down-regulation
Atypical_PIKK_ATR_ATR_ST	Q14676	MDC1	Q13535	ATR	T765	D769G	769	Missense	distal	4	no	10.296	11.117	EPSD	ICGC;COSMIC	10.658	Gain
Atypical_PIKK_ATR_ATR_ST	Q14676	MDC1	Q13535	ATR	S874	D868N	868	Missense	distal	-6	no	11.030	11.032	EPSD	ICGC;COSMIC	10.658	Up-regulation
Atypical_PIKK_ATR_ATR_ST	Q14676	MDC1	Q13535	ATR	T946	E952Q	952	Missense	distal	6	no	13.763	13.550	EPSD	ICGC;COSMIC	10.658	Down-regulation
Atypical_PIKK_ATR_ATR_ST	Q14676	MDC1	Q13535	ATR	S955	E952Q	952	Missense	distal	-3	no	16.060	16.212	EPSD	ICGC;COSMIC	10.658	Up-regulation
Atypical_PIKK_ATR_ATR_ST	Q14676	MDC1	Q13535	ATR	S988	G987R	987	Missense	proximal	-1	no	12.254	12.287	EPSD	ICGC;COSMIC	10.658	Up-regulation
Atypical_PIKK_ATR_ATR_ST	Q14676	MDC1	Q13535	ATR	S1057	P1063S	1063	Missense	distal	6	no	12.221	12.518	EPSD	ICGC	10.658	Up-regulation
Atypical_PIKK_ATR_ATR_ST	Q14676	MDC1	Q13535	ATR	S1184	T1187A	1187	Missense	distal	3	no	13.414	13.102	EPSD	ICGC	10.658	Down-regulation
Atypical_PIKK_ATR_ATR_ST	Q14676	MDC1	Q13535	ATR	T1187	S1194Y	1194	Missense	distal	7	no	10.621	10.806	EPSD	ICGC	10.658	Gain
Atypical_PIKK_ATR_ATR_ST	Q14676	MDC1	Q13535	ATR	S1194	T1187A	1187	Missense	distal	-7	no	10.954	10.977	EPSD	ICGC	10.658	Up-regulation
Atypical_PIKK_ATR_ATR_ST	Q14676	MDC1	Q13535	ATR	S1194	S1194Y	1194	Missense	central	0	yes	10.954	0.000	EPSD	ICGC	10.658	Loss
Atypical_PIKK_ATR_ATR_ST	Q14676	MDC1	Q13535	ATR	T1269	S1276P	1276	Missense	distal	7	no	11.956	12.119	EPSD	ICGC	10.658	Up-regulation
Atypical_PIKK_ATR_ATR_ST	Q14676	MDC1	Q13535	ATR	S1276	S1276P	1276	Missense	central	0	yes	11.168	0.000	EPSD	ICGC	10.658	Loss
Atypical_PIKK_ATR_ATR_ST	Q14676	MDC1	Q13535	ATR	S1702	Q1708L	1708	Missense	distal	6	no	12.752	12.656	EPSD	ICGC;COSMIC	10.658	Down-regulation
Atypical_PIKK_ATR_ATR_ST	Q14676	MDC1	Q13535	ATR	S1702	P1709S	1709	Missense	distal	7	no	12.752	12.589	EPSD	ICGC	10.658	Down-regulation
Atypical_PIKK_ATR_ATR_ST	Q14676	MDC1	Q13535	ATR	S1711	Q1708L	1708	Missense	distal	-3	no	12.191	12.410	EPSD	ICGC;COSMIC	10.658	Up-regulation
Atypical_PIKK_ATR_ATR_ST	Q14676	MDC1	Q13535	ATR	S1711	P1709S	1709	Missense	proximal	-2	no	12.191	12.140	EPSD	ICGC	10.658	Down-regulation
Atypical_PIKK_ATR_ATR_ST	Q14676	MDC1	Q13535	ATR	T1716	P1709S	1709	Missense	distal	-7	no	12.022	11.995	EPSD	ICGC	10.658	Down-regulation
Atypical_PIKK_ATR_ATR_ST	Q14676	MDC1	Q13535	ATR	S1766	A1769V	1769	Missense	distal	3	no	10.153	10.914	EPSD	ICGC;COSMIC	10.658	Gain
Atypical_PIKK_ATR_ATR_ST	Q14676	MDC1	Q13535	ATR	S1766	A1769S	1769	Missense	distal	3	no	10.153	10.814	EPSD	ICGC	10.658	Gain
Atypical_PIKK_ATR_ATR_ST	Q14676	MDC1	Q13535	ATR	T1781	A1774D	1774	Missense	distal	-7	no	12.451	12.469	EPSD	ICGC	10.658	Up-regulation
Atypical_PIKK_ATR_ATR_ST	Q6PGQ7	BORA	Q13535	ATR	S233	L232F	232	Missense	proximal	-1	no	12.040	11.806	EPSD	ICGC	10.658	Down-regulation
Atypical_PIKK_ATR_ATR_ST	Q6PGQ7	BORA	Q13535	ATR	T243	S250Y	250	Missense	distal	7	no	12.927	13.113	EPSD	ICGC	10.658	Up-regulation
Atypical_PIKK_ATR_ATR_ST	Q6PGQ7	BORA	Q13535	ATR	T243	G247V	247	Missense	distal	4	no	12.927	12.321	EPSD	ICGC	10.658	Down-regulation
Atypical_PIKK_ATR_ATR_ST	Q6PGQ7	BORA	Q13535	ATR	S245	S250Y	250	Missense	distal	5	no	10.958	10.980	EPSD	ICGC	10.658	Up-regulation
Atypical_PIKK_ATR_ATR_ST	Q6PGQ7	BORA	Q13535	ATR	S245	G247V	247	Missense	proximal	2	no	10.958	10.657	EPSD	ICGC	10.658	Loss
Atypical_PIKK_ATR_ATR_ST	Q6PGQ7	BORA	Q13535	ATR	S245	S252N	252	Missense	distal	7	no	10.958	11.340	EPSD	ICGC	10.658	Up-regulation
Atypical_PIKK_ATR_ATR_ST	Q6PGQ7	BORA	Q13535	ATR	S262	S262R	262	Missense	central	0	yes	11.833	0.000	EPSD	ICGC	10.658	Loss
Atypical_PIKK_ATR_ATR_ST	Q6PGQ7	BORA	Q13535	ATR	S325	P326Q	326	Missense	proximal	1	no	8.358	13.225	EPSD	ICGC	10.658	Gain
Atypical_PIKK_ATR_ATR_ST	Q6PGQ7	BORA	Q13535	ATR	T501	M495I	495	Missense	distal	-6	no	15.480	15.499	PhosphoSitePlus	ICGC	10.658	Up-regulation
Atypical_PIKK_ATR_ATR_ST	Q13098	GPS1	Q13535	ATR	T367	R363Q	363	Missense	distal	-4	no	10.622	10.804	EPSD	ICGC;COSMIC	10.658	Gain
Atypical_PIKK_ATR_ATR_ST	O43542	XRCC3	Q13535	ATR	S225	C221Y	221	Missense	distal	-4	no	16.260	15.154	PhosphoSitePlus	ICGC;GDSC;CCLE	10.658	Down-regulation
Atypical_PIKK_ATR_ATR_ST	O00213	APBB1	Q13535	ATR	S175	L173P	173	Missense	proximal	-2	no	11.825	11.174	EPSD	ICGC;COSMIC	10.658	Down-regulation
Atypical_PIKK_ATR_ATR_ST	O00213	APBB1	Q13535	ATR	S175	P176H	176	Missense	proximal	1	no	11.825	-0.826	EPSD	ICGC;COSMIC	10.658	Loss
Atypical_PIKK_ATR_ATR_ST	P55072	VCP	Q13535	ATR	S78	V71I	71	Missense	distal	-7	no	12.232	12.171	EPSD	ICGC;COSMIC	10.658	Down-regulation
Atypical_PIKK_ATR_ATR_ST	P55072	VCP	Q13535	ATR	S78	D75E	75	Missense	distal	-3	no	12.232	11.639	EPSD	ICGC;COSMIC	10.658	Down-regulation
Atypical_PIKK_ATR_ATR_ST	P55072	VCP	Q13535	ATR	S78	D79V	79	Missense	proximal	1	no	12.232	-2.049	EPSD	ICGC;COSMIC	10.658	Loss
Atypical_PIKK_ATR_ATR_ST	P55072	VCP	Q13535	ATR	S78	L72F	72	Missense	distal	-6	no	12.232	12.202	EPSD	ICGC	10.658	Down-regulation
Atypical_PIKK_ATR_ATR_ST	P55072	VCP	Q13535	ATR	S326	R322W	322	Missense	distal	-4	no	15.043	15.501	EPSD	ICGC;COSMIC	10.658	Up-regulation
Atypical_PIKK_ATR_ATR_ST	P55072	VCP	Q13535	ATR	T347	M344I	344	Missense	distal	-3	no	12.211	12.220	EPSD	ICGC;COSMIC	10.658	Up-regulation
Atypical_PIKK_ATR_ATR_ST	P55072	VCP	Q13535	ATR	S765	T761N	761	Missense	distal	-4	no	10.946	11.256	EPSD	ICGC;COSMIC	10.658	Up-regulation
Atypical_PIKK_ATR_ATR_ST	P55072	VCP	Q13535	ATR	S784	P783T	783	Missense	proximal	-1	no	15.380	15.211	PhosphoSitePlus	ICGC;COSMIC	10.658	Down-regulation
Atypical_PIKK_ATR_ATR_ST	Q8TAQ2	SMARCC2	Q13535	ATR	S175	H176N	176	Missense	proximal	1	no	0.163	13.405	EPSD	ICGC;COSMIC	10.658	Gain
Atypical_PIKK_ATR_ATR_ST	Q8TAQ2	SMARCC2	Q13535	ATR	T230	T230N	230	Missense	central	0	yes	14.294	0.000	EPSD	ICGC	10.658	Loss
Atypical_PIKK_ATR_ATR_ST	Q8TAQ2	SMARCC2	Q13535	ATR	S302	R301H	301	Missense	proximal	-1	no	11.057	10.951	EPSD	ICGC;COSMIC	10.658	Down-regulation
Atypical_PIKK_ATR_ATR_ST	Q8TAQ2	SMARCC2	Q13535	ATR	S302	P305H	305	Missense	distal	3	no	11.057	11.093	EPSD	ICGC;COSMIC	10.658	Up-regulation
Atypical_PIKK_ATR_ATR_ST	Q8TAQ2	SMARCC2	Q13535	ATR	S302	S302Y	302	Missense	central	0	yes	11.057	0.000	EPSD	ICGC	10.658	Loss
Atypical_PIKK_ATR_ATR_ST	Q8TAQ2	SMARCC2	Q13535	ATR	S347	P346T	346	Missense	proximal	-1	no	12.264	12.096	EPSD	ICGC;COSMIC	10.658	Down-regulation
Atypical_PIKK_ATR_ATR_ST	Q8TAQ2	SMARCC2	Q13535	ATR	T400	E397K	397	Missense	distal	-3	no	10.814	10.539	EPSD	ICGC	10.658	Loss
Atypical_PIKK_ATR_ATR_ST	Q8TAQ2	SMARCC2	Q13535	ATR	T400	G404R	404	Missense	distal	4	no	10.814	10.097	EPSD	ICGC;COSMIC	10.658	Loss
Atypical_PIKK_ATR_ATR_ST	Q8TAQ2	SMARCC2	Q13535	ATR	S555	P562A	562	Missense	distal	7	no	15.275	15.183	EPSD	ICGC	10.658	Down-regulation
Atypical_PIKK_ATR_ATR_ST	Q8TAQ2	SMARCC2	Q13535	ATR	S841	G843E	843	Missense	proximal	2	no	10.754	10.883	EPSD	ICGC;COSMIC	10.658	Up-regulation
Atypical_PIKK_ATR_ATR_ST	Q8TAQ2	SMARCC2	Q13535	ATR	S841	E840K	840	Missense	proximal	-1	no	10.754	10.505	EPSD	ICGC;COSMIC	10.658	Loss
Atypical_PIKK_ATR_ATR_ST	Q8TAQ2	SMARCC2	Q13535	ATR	S841	K846R	846	Missense	distal	5	no	10.754	10.761	EPSD	ICGC	10.658	Up-regulation
Atypical_PIKK_ATR_ATR_ST	Q8TAQ2	SMARCC2	Q13535	ATR	S969	P974T	974	Missense	distal	5	no	16.789	16.786	PhosphoSitePlus	ICGC	10.658	Down-regulation
Atypical_PIKK_ATR_ATR_ST	Q8N163	CCAR2	Q13535	ATR	S43	P37S	37	Missense	distal	-6	no	12.854	12.809	EPSD	ICGC;COSMIC	10.658	Down-regulation
Atypical_PIKK_ATR_ATR_ST	Q8N163	CCAR2	Q13535	ATR	S302	D303Y	303	Missense	proximal	1	no	10.933	10.033	EPSD	ICGC;COSMIC	10.658	Loss
Atypical_PIKK_ATR_ATR_ST	O75717	WDHD1	Q13535	ATR	S387	D385E	385	Missense	proximal	-2	no	11.514	11.418	EPSD	ICGC	10.658	Down-regulation
Atypical_PIKK_ATR_ATR_ST	O75717	WDHD1	Q13535	ATR	S416	N410K	410	Missense	distal	-6	no	16.623	16.566	EPSD	ICGC	10.658	Down-regulation
Atypical_PIKK_ATR_ATR_ST	O75717	WDHD1	Q13535	ATR	S416	N410H	410	Missense	distal	-6	no	16.623	16.646	EPSD	ICGC	10.658	Up-regulation
Atypical_PIKK_ATR_ATR_ST	P49006	MARCKSL1	Q13535	ATR	S71	S71R	71	Missense	central	0	yes	16.420	0.000	PhosphoSitePlus	ICGC	10.658	Loss
Atypical_PIKK_ATR_ATR_ST	P49006	MARCKSL1	Q13535	ATR	S71	P67T	67	Missense	distal	-4	no	16.420	16.008	PhosphoSitePlus	ICGC	10.658	Down-regulation
Atypical_PIKK_ATR_ATR_ST	P49006	MARCKSL1	Q13535	ATR	T85	K83T	83	Missense	proximal	-2	no	11.224	11.131	EPSD	ICGC;COSMIC	10.658	Down-regulation
Atypical_PIKK_ATR_ATR_ST	P49006	MARCKSL1	Q13535	ATR	S116	P121L	121	Missense	distal	5	no	10.725	10.720	EPSD	ICGC;COSMIC	10.658	Down-regulation
Atypical_PIKK_ATR_ATR_ST	P49006	MARCKSL1	Q13535	ATR	S116	S119C	119	Missense	distal	3	no	10.725	10.423	EPSD	ICGC;COSMIC	10.658	Loss
Atypical_PIKK_ATR_ATR_ST	P49006	MARCKSL1	Q13535	ATR	S116	S117F	117	Missense	proximal	1	no	10.725	10.018	EPSD	ICGC;COSMIC	10.658	Loss
Atypical_PIKK_ATR_ATR_ST	P49006	MARCKSL1	Q13535	ATR	S116	R109Q	109	Missense	distal	-7	no	10.725	10.757	EPSD	ICGC	10.658	Up-regulation
Atypical_PIKK_ATR_ATR_ST	P49006	MARCKSL1	Q13535	ATR	T148	P149S	149	Missense	proximal	1	no	10.983	9.874	EPSD	ICGC;COSMIC	10.658	Loss
Atypical_PIKK_ATR_ATR_ST	P49006	MARCKSL1	Q13535	ATR	T148	Q141K	141	Missense	distal	-7	no	10.983	11.011	EPSD	ICGC;COSMIC	10.658	Up-regulation
Atypical_PIKK_ATR_ATR_ST	P49006	MARCKSL1	Q13535	ATR	T148	G143W	143	Missense	distal	-5	no	10.983	11.180	EPSD	ICGC;COSMIC	10.658	Up-regulation
Atypical_PIKK_ATR_ATR_ST	P49006	MARCKSL1	Q13535	ATR	S151	P149S	149	Missense	proximal	-2	no	16.276	16.225	EPSD	ICGC;COSMIC	10.658	Down-regulation
Atypical_PIKK_ATR_ATR_ST	P49006	MARCKSL1	Q13535	ATR	T178	S180L	180	Missense	proximal	2	no	11.017	10.052	EPSD	ICGC;COSMIC	10.658	Loss
Atypical_PIKK_ATR_ATR_ST	P49006	MARCKSL1	Q13535	ATR	T178	S184I	184	Missense	distal	6	no	11.017	10.744	EPSD	ICGC;COSMIC	10.658	Down-regulation
STE_STE20_SLK_STK10_ST	P35241	RDX	O94804	STK10	T66	Q67K	67	Missense	proximal	1	no	2.772	2.766	EPSD	ICGC;COSMIC	2.434	Down-regulation
STE_STE20_SLK_STK10_ST	P35241	RDX	O94804	STK10	T66	K64N	64	Missense	proximal	-2	no	2.772	2.315	EPSD	ICGC;COSMIC	2.434	Loss
STE_STE20_SLK_STK10_ST	P35241	RDX	O94804	STK10	T564	A557E	557	Missense	distal	-7	no	8.215	8.161	PhosphoSitePlus	ICGC	2.434	Down-regulation
STE_STE20_SLK_STK10_ST	P15311	EZR	O94804	STK10	S66	L59M	59	Missense	distal	-7	no	2.416	2.453	EPSD	ICGC	2.434	Gain
STE_STE20_SLK_STK10_ST	P15311	EZR	O94804	STK10	S66	A67V	67	Missense	proximal	1	no	2.416	3.118	EPSD	ICGC	2.434	Gain
STE_STE20_SLK_STK10_ST	P15311	EZR	O94804	STK10	S66	V65G	65	Missense	proximal	-1	no	2.416	2.477	EPSD	ICGC;COSMIC	2.434	Gain
STE_STE20_SLK_STK10_ST	P15311	EZR	O94804	STK10	T235	K237N	237	Missense	proximal	2	no	3.447	3.377	EPSD	ICGC;COSMIC	2.434	Down-regulation
STE_STE20_SLK_STK10_ST	P15311	EZR	O94804	STK10	T497	A494T	494	Missense	distal	-3	no	3.307	3.295	EPSD	ICGC;COSMIC	2.434	Down-regulation
STE_STE20_SLK_STK10_ST	P15311	EZR	O94804	STK10	T497	S504C	504	Missense	distal	7	no	3.307	3.316	EPSD	ICGC;COSMIC	2.434	Up-regulation
STE_STE20_SLK_STK10_ST	P15311	EZR	O94804	STK10	T567	T567M	567	Missense	central	0	yes	8.527	0.000	PhosphoSitePlus	ICGC;COSMIC	2.434	Loss
STE_STE20_SLK_STK10_ST	P15311	EZR	O94804	STK10	T567	Q573K	573	Missense	distal	6	no	8.527	8.524	PhosphoSitePlus	ICGC	2.434	Down-regulation
STE_STE20_SLK_STK10_ST	P53350	PLK1	O94804	STK10	T341	T341I	341	Missense	central	0	yes	2.783	0.000	EPSD	ICGC;COSMIC	2.434	Loss
STE_STE20_SLK_STK10_ST	P53350	PLK1	O94804	STK10	S383	Q380K	380	Missense	distal	-3	no	1.045	2.488	EPSD	ICGC;COSMIC	2.434	Gain
STE_STE20_SLK_STK10_ST	P26038	MSN	O94804	STK10	S74	R81H	81	Missense	distal	7	no	3.891	3.868	EPSD	ICGC;COSMIC	2.434	Down-regulation
STE_STE20_SLK_STK10_ST	P26038	MSN	O94804	STK10	S74	K79N	79	Missense	distal	5	no	3.891	3.849	EPSD	ICGC;COSMIC	2.434	Down-regulation
STE_STE20_SLK_STK10_ST	P26038	MSN	O94804	STK10	T558	D554N	554	Missense	distal	-4	no	8.375	7.669	PhosphoSitePlus	ICGC;COSMIC	2.434	Down-regulation
STE_STE20_SLK_STK10_ST	P26038	MSN	O94804	STK10	T558	T558I	558	Missense	central	0	yes	8.375	0.000	PhosphoSitePlus	ICGC;COSMIC	2.434	Loss
TK_Abl_ABL2_Y	P04040	CAT	P42684	ABL2	Y231	G227V	227	Missense	distal	-4	no	36.242	32.303	PhosphoSitePlus;EPSD	ICGC	19.113	Down-regulation
TK_Abl_ABL2_Y	P04040	CAT	P42684	ABL2	Y386	Q387H	387	Missense	proximal	1	no	33.162	32.506	EPSD;PhosphoSitePlus	ICGC;COSMIC	19.113	Down-regulation
TK_Abl_ABL2_Y	P04040	CAT	P42684	ABL2	Y386	G390C	390	Missense	distal	4	no	33.162	32.707	EPSD;PhosphoSitePlus	ICGC	19.113	Down-regulation
TK_Abl_ABL2_Y	P04040	CAT	P42684	ABL2	Y386	D389N	389	Missense	distal	3	no	33.162	31.586	EPSD;PhosphoSitePlus	ICGC	19.113	Down-regulation
TK_Abl_ABL2_Y	P17676	CEBPB	P42684	ABL2	Y78	I73M	73	Missense	distal	-5	no	33.919	33.081	PhosphoSitePlus	ICGC	19.113	Down-regulation
TK_Abl_ABL2_Y	P17676	CEBPB	P42684	ABL2	Y137	P134L	134	Missense	distal	-3	no	21.513	21.604	EPSD	ICGC	19.113	Up-regulation
TK_Abl_ABL2_Y	P17676	CEBPB	P42684	ABL2	Y137	A135T	135	Missense	proximal	-2	no	21.513	21.668	EPSD	ICGC;COSMIC	19.113	Up-regulation
TK_Abl_ABL2_Y	P17676	CEBPB	P42684	ABL2	Y137	L142P	142	Missense	distal	5	no	21.513	19.220	EPSD	ICGC;COSMIC	19.113	Down-regulation
TK_Abl_ABL2_Y	P01112	HRAS	P42684	ABL2	Y137	G138R	138	Missense	proximal	1	no	31.133	29.098	PhosphoSitePlus	ICGC	19.113	Down-regulation
TK_Abl_ABL2_Y	P46108	CRK	P42684	ABL2	Y221	T228I	228	Missense	distal	7	no	38.776	39.050	PhosphoSitePlus	ICGC;COSMIC	19.113	Up-regulation
TK_Abl_ABL2_Y	P46108	CRK	P42684	ABL2	Y239	Y239F	239	Missense	central	0	yes	22.449	0.000	EPSD	ICGC;COSMIC	19.113	Loss
TK_Abl_ABL2_Y	P10636	MAPT	P42684	ABL2	Y514	G521R	521	Missense	distal	7	no	39.019	38.625	EPSD	ICGC;COSMIC	19.113	Down-regulation
TK_Abl_ABL2_Y	O14818	PSMA7	P42684	ABL2	Y153	A160T	160	Missense	distal	7	no	35.748	35.749	PhosphoSitePlus	ICGC	19.113	Up-regulation
TK_Abl_ABL2_Y	P17931	LGALS3	P42684	ABL2	Y79	G85S	85	Missense	distal	6	no	38.241	38.452	EPSD;PhosphoSitePlus	ICGC;COSMIC	19.113	Up-regulation
TK_Abl_ABL2_Y	P17931	LGALS3	P42684	ABL2	Y107	Y101S	101	Missense	distal	-6	no	36.281	38.464	EPSD	ICGC;COSMIC	19.113	Up-regulation
TK_Abl_ABL2_Y	P17931	LGALS3	P42684	ABL2	Y107	P113T	113	Missense	distal	6	no	36.281	36.727	EPSD	ICGC;COSMIC	19.113	Up-regulation
TK_Abl_ABL2_Y	P17931	LGALS3	P42684	ABL2	Y118	G124V	124	Missense	distal	6	no	37.541	37.210	PhosphoSitePlus;EPSD	ICGC	19.113	Down-regulation
TK_Abl_ABL2_Y	P17931	LGALS3	P42684	ABL2	Y118	G125V	125	Missense	distal	7	no	37.541	37.657	PhosphoSitePlus;EPSD	ICGC;COSMIC	19.113	Up-regulation
TK_Abl_ABL2_Y	P17931	LGALS3	P42684	ABL2	Y118	P113T	113	Missense	distal	-5	no	37.541	37.535	PhosphoSitePlus;EPSD	ICGC;COSMIC	19.113	Down-regulation
TK_Abl_ABL2_Y	P09619	PDGFRB	P42684	ABL2	Y581	H577N	577	Missense	distal	-4	no	19.741	18.958	EPSD	ICGC	19.113	Loss
TK_Abl_ABL2_Y	P09619	PDGFRB	P42684	ABL2	Y581	P584H	584	Missense	distal	3	no	19.741	12.092	EPSD	ICGC;COSMIC	19.113	Loss
TK_Abl_ABL2_Y	P09619	PDGFRB	P42684	ABL2	Y716	A719P	719	Missense	distal	3	no	16.148	23.762	EPSD	ICGC;COSMIC	19.113	Gain
TK_Abl_ABL2_Y	P09619	PDGFRB	P42684	ABL2	Y771	A764E	764	Missense	distal	-7	no	20.077	21.702	EPSD	ICGC	19.113	Up-regulation
TK_Abl_ABL2_Y	P09619	PDGFRB	P42684	ABL2	Y934	H928R	928	Missense	distal	-6	no	26.698	26.537	EPSD	ICGC;COSMIC	19.113	Down-regulation
TK_Abl_ABL2_Y	P07203	GPX1	P42684	ABL2	Y98	L96R	96	Missense	proximal	-2	no	32.570	33.325	PhosphoSitePlus	ICGC;COSMIC	19.113	Up-regulation
TK_Abl_ABL2_Y	P05556	ITGB1	P42684	ABL2	Y783	P781A	781	Missense	proximal	-2	no	26.275	26.220	PhosphoSitePlus	ICGC;COSMIC	19.113	Down-regulation
TK_Abl_ABL2_Y	P05556	ITGB1	P42684	ABL2	Y783	V787I	787	Missense	distal	4	no	26.275	26.833	PhosphoSitePlus	ICGC;COSMIC;GDSC;CCLE	19.113	Up-regulation
TK_Abl_ABL2_Y	P05556	ITGB1	P42684	ABL2	Y783	P781L	781	Missense	proximal	-2	no	26.275	25.747	PhosphoSitePlus	ICGC;COSMIC	19.113	Down-regulation
TKL_LISK_LIMK_LIMK1_ST	P60981	DSTN	P53667	LIMK1	S3	V7I	7	Missense	distal	4	no	3.818	3.635	PhosphoSitePlus	ICGC	-0.776	Down-regulation
TK_Src_SrcB_HCK_Y	P00519	ABL1	P08631	HCK	Y70	F72V	72	Missense	proximal	2	no	11.596	12.019	EPSD;PhosphoSitePlus	ICGC;COSMIC	7.597	Up-regulation
TK_Src_SrcB_HCK_Y	P00519	ABL1	P08631	HCK	Y70	D71N	71	Missense	proximal	1	no	11.596	11.585	EPSD;PhosphoSitePlus	ICGC;COSMIC	7.597	Down-regulation
TK_Src_SrcB_HCK_Y	P00519	ABL1	P08631	HCK	Y70	Y70H	70	Missense	central	0	yes	11.596	0.000	EPSD;PhosphoSitePlus	ICGC;COSMIC	7.597	Loss
TK_Src_SrcB_HCK_Y	P00519	ABL1	P08631	HCK	Y70	S75R	75	Missense	distal	5	no	11.596	10.903	EPSD;PhosphoSitePlus	ICGC;COSMIC	7.597	Down-regulation
TK_Src_SrcB_HCK_Y	P00519	ABL1	P08631	HCK	Y70	V67F	67	Missense	distal	-3	no	11.596	10.076	EPSD;PhosphoSitePlus	ICGC;COSMIC	7.597	Down-regulation
TK_Src_SrcB_HCK_Y	P00519	ABL1	P08631	HCK	Y115	V111L	111	Missense	distal	-4	no	11.227	11.250	EPSD;PhosphoSitePlus	ICGC;COSMIC	7.597	Up-regulation
TK_Src_SrcB_HCK_Y	P00519	ABL1	P08631	HCK	Y115	V119F	119	Missense	distal	4	no	11.227	9.189	EPSD;PhosphoSitePlus	ICGC	7.597	Down-regulation
TK_Src_SrcB_HCK_Y	P00519	ABL1	P08631	HCK	Y128	R134L	134	Missense	distal	6	no	11.768	11.033	EPSD;PhosphoSitePlus	ICGC;COSMIC	7.597	Down-regulation
TK_Src_SrcB_HCK_Y	P00519	ABL1	P08631	HCK	Y128	P131S	131	Missense	distal	3	no	11.768	12.751	EPSD;PhosphoSitePlus	ICGC;GDSC	7.597	Up-regulation
TK_Src_SrcB_HCK_Y	P00519	ABL1	P08631	HCK	Y139	G144W	144	Missense	distal	5	no	11.438	10.745	EPSD;PhosphoSitePlus	ICGC	7.597	Down-regulation
TK_Src_SrcB_HCK_Y	P00519	ABL1	P08631	HCK	Y139	R134L	134	Missense	distal	-5	no	11.438	11.393	EPSD;PhosphoSitePlus	ICGC;COSMIC	7.597	Down-regulation
TK_Src_SrcB_HCK_Y	P00519	ABL1	P08631	HCK	Y139	G144R	144	Missense	distal	5	no	11.438	10.966	EPSD;PhosphoSitePlus	ICGC	7.597	Down-regulation
TK_Src_SrcB_HCK_Y	P00519	ABL1	P08631	HCK	Y172	G169W	169	Missense	distal	-3	no	10.715	7.581	EPSD;PhosphoSitePlus	ICGC;COSMIC	7.597	Loss
TK_Src_SrcB_HCK_Y	P00519	ABL1	P08631	HCK	Y172	R170G	170	Missense	proximal	-2	no	10.715	11.160	EPSD;PhosphoSitePlus	ICGC;COSMIC	7.597	Up-regulation
TK_Src_SrcB_HCK_Y	P00519	ABL1	P08631	HCK	Y185	E189G	189	Missense	distal	4	no	10.695	10.509	EPSD;PhosphoSitePlus	ICGC;COSMIC	7.597	Down-regulation
TK_Src_SrcB_HCK_Y	P00519	ABL1	P08631	HCK	Y185	V186I	186	Missense	proximal	1	no	10.695	10.772	EPSD;PhosphoSitePlus	ICGC;COSMIC	7.597	Up-regulation
TK_Src_SrcB_HCK_Y	P00519	ABL1	P08631	HCK	Y215	P216L	216	Missense	proximal	1	no	9.755	9.796	EPSD;PhosphoSitePlus	ICGC	7.597	Up-regulation
TK_Src_SrcB_HCK_Y	P00519	ABL1	P08631	HCK	Y226	Y232C	232	Missense	distal	6	no	8.852	9.172	EPSD;PhosphoSitePlus	ICGC;COSMIC	7.597	Up-regulation
TK_Src_SrcB_HCK_Y	P00519	ABL1	P08631	HCK	Y226	D233N	233	Missense	distal	7	no	8.852	8.946	EPSD;PhosphoSitePlus	ICGC;COSMIC	7.597	Up-regulation
TK_Src_SrcB_HCK_Y	P00519	ABL1	P08631	HCK	Y226	D233Y	233	Missense	distal	7	no	8.852	8.640	EPSD;PhosphoSitePlus	ICGC	7.597	Down-regulation
TK_Src_SrcB_HCK_Y	P11274	BCR	P08631	HCK	Y177	F182L	182	Missense	distal	5	no	11.230	11.940	PhosphoSitePlus	ICGC;COSMIC	7.597	Up-regulation
TK_Src_SrcB_HCK_Y	Q92556	ELMO1	P08631	HCK	Y18	A17T	17	Missense	proximal	-1	no	10.836	10.845	EPSD;PhosphoSitePlus	ICGC;COSMIC	7.597	Up-regulation
TK_Src_SrcB_HCK_Y	Q92556	ELMO1	P08631	HCK	Y216	A220T	220	Missense	distal	4	no	10.924	9.443	EPSD;PhosphoSitePlus	ICGC;COSMIC	7.597	Down-regulation
TK_Src_SrcB_HCK_Y	Q92556	ELMO1	P08631	HCK	Y395	R397W	397	Missense	proximal	2	no	11.625	11.061	EPSD;PhosphoSitePlus	ICGC;COSMIC	7.597	Down-regulation
TK_Src_SrcB_HCK_Y	Q92556	ELMO1	P08631	HCK	Y395	K389R	389	Missense	distal	-6	no	11.625	11.684	EPSD;PhosphoSitePlus	ICGC	7.597	Up-regulation
TK_Src_SrcB_HCK_Y	Q92556	ELMO1	P08631	HCK	Y395	N402K	402	Missense	distal	7	no	11.625	11.456	EPSD;PhosphoSitePlus	ICGC	7.597	Down-regulation
TK_Src_SrcB_HCK_Y	Q92556	ELMO1	P08631	HCK	Y395	A388V	388	Missense	distal	-7	no	11.625	9.362	EPSD;PhosphoSitePlus	ICGC;COSMIC	7.597	Down-regulation
TK_Src_SrcB_HCK_Y	P08631	HCK	P08631	HCK	Y51	A44S	44	Missense	distal	-7	no	11.142	9.869	EPSD	ICGC;COSMIC	7.597	Down-regulation
TK_Src_SrcB_HCK_Y	Q13444	ADAM15	P08631	HCK	Y735	S740L	740	Missense	distal	5	no	10.220	10.099	EPSD	ICGC;COSMIC	7.597	Down-regulation
TK_Src_SrcB_HCK_Y	Q13444	ADAM15	P08631	HCK	Y735	R736S	736	Missense	proximal	1	no	10.220	10.321	EPSD	ICGC;COSMIC	7.597	Up-regulation
TK_Src_SrcB_HCK_Y	P51692	STAT5B	P08631	HCK	Y392	R389G	389	Missense	distal	-3	no	3.883	7.731	EPSD	ICGC	7.597	Gain
TK_Src_SrcB_HCK_Y	P51692	STAT5B	P08631	HCK	Y699	A695S	695	Missense	distal	-4	no	11.353	11.326	PhosphoSitePlus	ICGC;COSMIC	7.597	Down-regulation
TK_Src_SrcB_HCK_Y	O15350	TP73	P08631	HCK	Y28	D30Y	30	Missense	proximal	2	no	10.670	10.445	PhosphoSitePlus	ICGC	7.597	Down-regulation
TK_Src_SrcB_HCK_Y	Q9UHD2	TBK1	P08631	HCK	Y394	T389I	389	Missense	distal	-5	no	12.008	12.073	EPSD;PhosphoSitePlus	ICGC;COSMIC	7.597	Up-regulation
TK_Src_SrcB_HCK_Y	Q9UHD2	TBK1	P08631	HCK	Y394	P400S	400	Missense	distal	6	no	12.008	11.832	EPSD;PhosphoSitePlus	ICGC;COSMIC	7.597	Down-regulation
TK_Src_SrcB_HCK_Y	Q9UHD2	TBK1	P08631	HCK	Y394	P400H	400	Missense	distal	6	no	12.008	11.944	EPSD;PhosphoSitePlus	ICGC;COSMIC	7.597	Down-regulation
TKL_MLK_MLK_MAP3K11_ST	Q16584	MAP3K11	Q16584	MAP3K11	S21	W16L	16	Missense	distal	-5	no	2.731	2.733	EPSD	ICGC;COSMIC	1.264	Up-regulation
TKL_MLK_MLK_MAP3K11_ST	Q16584	MAP3K11	Q16584	MAP3K11	S21	G27S	27	Missense	distal	6	no	2.731	3.027	EPSD	ICGC;COSMIC	1.264	Up-regulation
TKL_MLK_MLK_MAP3K11_ST	Q16584	MAP3K11	Q16584	MAP3K11	S21	G27C	27	Missense	distal	6	no	2.731	2.864	EPSD	ICGC;COSMIC	1.264	Up-regulation
TKL_MLK_MLK_MAP3K11_ST	Q16584	MAP3K11	Q16584	MAP3K11	S281	A287V	287	Missense	distal	6	no	4.392	4.045	PhosphoSitePlus;EPSD	ICGC	1.264	Down-regulation
TKL_MLK_MLK_MAP3K11_ST	Q16584	MAP3K11	Q16584	MAP3K11	S281	T285N	285	Missense	distal	4	no	4.392	4.238	PhosphoSitePlus;EPSD	ICGC	1.264	Down-regulation
TKL_MLK_MLK_MAP3K11_ST	Q13526	PIN1	Q16584	MAP3K11	S19	V22L	22	Missense	distal	3	no	1.411	1.591	EPSD	ICGC;COSMIC	1.264	Up-regulation
TKL_MLK_MLK_MAP3K11_ST	Q13526	PIN1	Q16584	MAP3K11	S38	A31S	31	Missense	distal	-7	no	1.363	1.353	EPSD	ICGC	1.264	Down-regulation
TKL_MLK_MLK_MAP3K11_ST	Q13526	PIN1	Q16584	MAP3K11	S38	W34L	34	Missense	distal	-4	no	1.363	1.365	EPSD	ICGC;COSMIC	1.264	Up-regulation
TKL_MLK_MLK_MAP3K11_ST	Q13526	PIN1	Q16584	MAP3K11	S108	A107T	107	Missense	proximal	-1	no	2.412	2.254	EPSD	ICGC;COSMIC	1.264	Down-regulation
TKL_MLK_MLK_MAP3K11_ST	Q13526	PIN1	Q16584	MAP3K11	S108	Q109H	109	Missense	proximal	1	no	2.412	2.409	EPSD	ICGC	1.264	Down-regulation
TKL_MLK_MLK_MAP3K11_ST	Q13526	PIN1	Q16584	MAP3K11	S111	Q109H	109	Missense	proximal	-2	no	1.102	1.265	EPSD	ICGC	1.264	Gain
TKL_MLK_MLK_MAP3K11_ST	Q13526	PIN1	Q16584	MAP3K11	S138	G144W	144	Missense	distal	6	no	3.911	3.964	PhosphoSitePlus	ICGC;COSMIC	1.264	Up-regulation
TKL_MLK_MLK_MAP3K11_ST	Q13526	PIN1	Q16584	MAP3K11	S138	G144E	144	Missense	distal	6	no	3.911	3.968	PhosphoSitePlus	ICGC;COSMIC	1.264	Up-regulation
TKL_MLK_MLK_MAP3K11_ST	Q13526	PIN1	Q16584	MAP3K11	S138	G144V	144	Missense	distal	6	no	3.911	3.756	PhosphoSitePlus	ICGC;COSMIC	1.264	Down-regulation
TKL_MLK_MLK_MAP3K11_ST	Q13526	PIN1	Q16584	MAP3K11	S147	G144W	144	Missense	distal	-3	no	1.655	1.704	EPSD	ICGC;COSMIC	1.264	Up-regulation
TKL_MLK_MLK_MAP3K11_ST	Q13526	PIN1	Q16584	MAP3K11	S147	G144E	144	Missense	distal	-3	no	1.655	1.733	EPSD	ICGC;COSMIC	1.264	Up-regulation
TKL_MLK_MLK_MAP3K11_ST	Q13526	PIN1	Q16584	MAP3K11	S147	G144V	144	Missense	distal	-3	no	1.655	1.810	EPSD	ICGC;COSMIC	1.264	Up-regulation
TKL_MLK_MLK_MAP3K11_ST	Q13131	PRKAA1	Q16584	MAP3K11	S65	R64Q	64	Missense	proximal	-1	no	1.690	1.657	EPSD	ICGC;COSMIC	1.264	Down-regulation
TKL_MLK_MLK_MAP3K11_ST	Q13131	PRKAA1	Q16584	MAP3K11	S65	V69A	69	Missense	distal	4	no	1.690	1.895	EPSD	ICGC	1.264	Up-regulation
TKL_MLK_MLK_MAP3K11_ST	Q13131	PRKAA1	Q16584	MAP3K11	T183	N189S	189	Missense	distal	6	no	3.774	3.986	PhosphoSitePlus	ICGC;COSMIC;CCLE	1.264	Up-regulation
TKL_MLK_MLK_MAP3K11_ST	Q13131	PRKAA1	Q16584	MAP3K11	T183	T183K	183	Missense	central	0	yes	3.774	0.000	PhosphoSitePlus	ICGC	1.264	Loss
TKL_MLK_MLK_MAP3K11_ST	Q13131	PRKAA1	Q16584	MAP3K11	S293	E290D	290	Missense	distal	-3	no	1.736	1.708	EPSD	ICGC;COSMIC	1.264	Down-regulation
TKL_MLK_MLK_MAP3K11_ST	Q13131	PRKAA1	Q16584	MAP3K11	S293	M298I	298	Missense	distal	5	no	1.736	1.738	EPSD	ICGC;COSMIC	1.264	Up-regulation
TKL_MLK_MLK_MAP3K11_ST	Q13131	PRKAA1	Q16584	MAP3K11	T382	R386H	386	Missense	distal	4	no	1.248	1.286	EPSD	ICGC;COSMIC	1.264	Gain
TKL_MLK_MLK_MAP3K11_ST	Q13131	PRKAA1	Q16584	MAP3K11	T382	R386C	386	Missense	distal	4	no	1.248	1.372	EPSD	ICGC;COSMIC	1.264	Gain
TKL_MLK_MLK_MAP3K11_ST	Q13131	PRKAA1	Q16584	MAP3K11	S498	S498C	498	Missense	central	0	yes	1.517	0.000	EPSD	ICGC;COSMIC	1.264	Loss
TKL_MLK_MLK_MAP3K11_ST	Q13131	PRKAA1	Q16584	MAP3K11	S498	R501P	501	Missense	distal	3	no	1.517	1.539	EPSD	ICGC;COSMIC	1.264	Up-regulation
TKL_MLK_MLK_MAP3K11_ST	Q13131	PRKAA1	Q16584	MAP3K11	S498	C503Y	503	Missense	distal	5	no	1.517	1.525	EPSD	ICGC	1.264	Up-regulation
TKL_MLK_MLK_MAP3K11_ST	Q13131	PRKAA1	Q16584	MAP3K11	S498	Y500C	500	Missense	proximal	2	no	1.517	1.543	EPSD	ICGC;COSMIC	1.264	Up-regulation
TKL_MLK_MLK_MAP3K11_ST	Q13131	PRKAA1	Q16584	MAP3K11	S498	R505M	505	Missense	distal	7	no	1.517	1.543	EPSD	ICGC	1.264	Up-regulation
Atypical_PDHK_PDHK_PDK3_ST	P29803	PDHA2	Q15120	PDK3	S128	L127R	127	Missense	proximal	-1	no	1.673	1.757	EPSD	ICGC;COSMIC	1.746	Gain
Atypical_PDHK_PDHK_PDK3_ST	P29803	PDHA2	Q15120	PDK3	S273	K275R	275	Missense	proximal	2	no	0.729	1.877	EPSD	ICGC;COSMIC	1.746	Gain
Atypical_PDHK_PDHK_PDK3_ST	P29803	PDHA2	Q15120	PDK3	T284	R286C	286	Missense	proximal	2	no	1.777	0.756	EPSD	ICGC;COSMIC	1.746	Loss
Atypical_PDHK_PDHK_PDK3_ST	P29803	PDHA2	Q15120	PDK3	T284	P277R	277	Missense	distal	-7	no	1.777	1.936	EPSD	ICGC;COSMIC	1.746	Up-regulation
Atypical_PDHK_PDHK_PDK3_ST	P29803	PDHA2	Q15120	PDK3	T284	R286S	286	Missense	proximal	2	no	1.777	1.407	EPSD	ICGC;COSMIC	1.746	Loss
Atypical_PDHK_PDHK_PDK3_ST	P29803	PDHA2	Q15120	PDK3	S291	R286C	286	Missense	distal	-5	no	10.124	9.443	EPSD;PhosphoSitePlus	ICGC;COSMIC	1.746	Down-regulation
Atypical_PDHK_PDHK_PDK3_ST	P29803	PDHA2	Q15120	PDK3	S291	R286S	286	Missense	distal	-5	no	10.124	9.908	EPSD;PhosphoSitePlus	ICGC;COSMIC	1.746	Down-regulation
Atypical_PDHK_PDHK_PDK3_ST	P29803	PDHA2	Q15120	PDK3	S293	R286C	286	Missense	distal	-7	no	2.409	2.255	EPSD	ICGC;COSMIC	1.746	Down-regulation
Atypical_PDHK_PDHK_PDK3_ST	P29803	PDHA2	Q15120	PDK3	S293	R286S	286	Missense	distal	-7	no	2.409	2.399	EPSD	ICGC;COSMIC	1.746	Down-regulation
Atypical_PDHK_PDHK_PDK3_ST	P29803	PDHA2	Q15120	PDK3	S310	I315V	315	Missense	distal	5	no	1.993	1.917	EPSD	ICGC;COSMIC	1.746	Down-regulation
Atypical_PDHK_PDHK_PDK3_ST	P29803	PDHA2	Q15120	PDK3	S310	R309T	309	Missense	proximal	-1	no	1.993	1.967	EPSD	ICGC;COSMIC	1.746	Down-regulation
AGC_DMPK_ROCK_ROCK2_ST	P19634	SLC9A1	O75116	ROCK2	S18	A24T	24	Missense	distal	6	no	23.187	23.289	EPSD	ICGC	20.789	Up-regulation
AGC_DMPK_ROCK_ROCK2_ST	P19634	SLC9A1	O75116	ROCK2	T653	R647Q	647	Missense	distal	-6	no	28.935	28.079	PhosphoSitePlus	ICGC;COSMIC;CCLE	20.789	Down-regulation
AGC_DMPK_ROCK_ROCK2_ST	P19634	SLC9A1	O75116	ROCK2	T653	Y649H	649	Missense	distal	-4	no	28.935	26.095	PhosphoSitePlus	ICGC;COSMIC	20.789	Down-regulation
AGC_DMPK_ROCK_ROCK2_ST	P19634	SLC9A1	O75116	ROCK2	S703	G702S	702	Missense	proximal	-1	no	20.803	20.518	EPSD	ICGC;COSMIC	20.789	Loss
AGC_DMPK_ROCK_ROCK2_ST	P19634	SLC9A1	O75116	ROCK2	S703	R700S	700	Missense	distal	-3	no	20.803	6.899	EPSD	ICGC	20.789	Loss
AGC_DMPK_ROCK_ROCK2_ST	P56817	BACE1	O75116	ROCK2	T47	P51T	51	Missense	distal	4	no	22.784	22.744	EPSD	ICGC;COSMIC	20.789	Down-regulation
AGC_DMPK_ROCK_ROCK2_ST	P56817	BACE1	O75116	ROCK2	S59	R57S	57	Missense	proximal	-2	no	23.679	12.768	EPSD	ICGC;COSMIC	20.789	Loss
AGC_DMPK_ROCK_ROCK2_ST	P56817	BACE1	O75116	ROCK2	S59	D65E	65	Missense	distal	6	no	23.679	22.728	EPSD	ICGC	20.789	Down-regulation
AGC_DMPK_ROCK_ROCK2_ST	P56817	BACE1	O75116	ROCK2	S59	V61M	61	Missense	proximal	2	no	23.679	23.854	EPSD	ICGC;COSMIC	20.789	Up-regulation
AGC_DMPK_ROCK_ROCK2_ST	P56817	BACE1	O75116	ROCK2	S59	R57H	57	Missense	proximal	-2	no	23.679	14.905	EPSD	ICGC	20.789	Loss
AGC_DMPK_ROCK_ROCK2_ST	Q92673	SORL1	O75116	ROCK2	S82	K80R	80	Missense	proximal	-2	no	14.622	23.575	EPSD	ICGC;COSMIC	20.789	Gain
AGC_DMPK_ROCK_ROCK2_ST	Q92673	SORL1	O75116	ROCK2	S732	R729L	729	Missense	distal	-3	no	33.466	13.837	EPSD	ICGC	20.789	Loss
AGC_DMPK_ROCK_ROCK2_ST	Q92673	SORL1	O75116	ROCK2	S732	R729G	729	Missense	distal	-3	no	33.466	25.282	EPSD	ICGC	20.789	Down-regulation
AGC_DMPK_ROCK_ROCK2_ST	Q92673	SORL1	O75116	ROCK2	S732	Y728C	728	Missense	distal	-4	no	33.466	32.432	EPSD	ICGC;COSMIC	20.789	Down-regulation
AGC_DMPK_ROCK_ROCK2_ST	Q92673	SORL1	O75116	ROCK2	S732	S737L	737	Missense	distal	5	no	33.466	33.098	EPSD	ICGC;COSMIC	20.789	Down-regulation
AGC_DMPK_ROCK_ROCK2_ST	Q92673	SORL1	O75116	ROCK2	S732	R729H	729	Missense	distal	-3	no	33.466	22.140	EPSD	ICGC;COSMIC	20.789	Down-regulation
AGC_DMPK_ROCK_ROCK2_ST	Q16555	DPYSL2	O75116	ROCK2	T13	K7T	7	Missense	distal	-6	no	50.561	49.970	EPSD	ICGC	20.789	Down-regulation
AGC_DMPK_ROCK_ROCK2_ST	Q16555	DPYSL2	O75116	ROCK2	T13	K20T	20	Missense	distal	7	no	50.561	51.546	EPSD	ICGC	20.789	Up-regulation
AGC_DMPK_ROCK_ROCK2_ST	Q16555	DPYSL2	O75116	ROCK2	T13	R11L	11	Missense	proximal	-2	no	50.561	36.300	EPSD	ICGC	20.789	Down-regulation
AGC_DMPK_ROCK_ROCK2_ST	Q16555	DPYSL2	O75116	ROCK2	S14	K7T	7	Missense	distal	-7	no	37.529	37.541	EPSD	ICGC	20.789	Up-regulation
AGC_DMPK_ROCK_ROCK2_ST	Q16555	DPYSL2	O75116	ROCK2	S14	K20T	20	Missense	distal	6	no	37.529	38.175	EPSD	ICGC	20.789	Up-regulation
AGC_DMPK_ROCK_ROCK2_ST	Q16555	DPYSL2	O75116	ROCK2	S14	R11L	11	Missense	distal	-3	no	37.529	17.900	EPSD	ICGC	20.789	Loss
AGC_DMPK_ROCK_ROCK2_ST	Q16555	DPYSL2	O75116	ROCK2	S14	G21V	21	Missense	distal	7	no	37.529	36.554	EPSD	ICGC;COSMIC	20.789	Down-regulation
AGC_DMPK_ROCK_ROCK2_ST	P10916	MYL2	O75116	ROCK2	S15	A10D	10	Missense	distal	-5	no	37.571	35.686	PhosphoSitePlus	ICGC;COSMIC	20.789	Down-regulation
AGC_DMPK_ROCK_ROCK2_ST	P10916	MYL2	O75116	ROCK2	T124	A127T	127	Missense	distal	3	no	23.427	22.054	EPSD	ICGC;COSMIC	20.789	Down-regulation
AGC_DMPK_ROCK_ROCK2_ST	O95644	NFATC1	O75116	ROCK2	S169	E163K	163	Missense	distal	-6	no	15.985	21.446	EPSD	ICGC;COSMIC	20.789	Gain
AGC_DMPK_ROCK_ROCK2_ST	O95644	NFATC1	O75116	ROCK2	S169	D167Y	167	Missense	proximal	-2	no	15.985	21.248	EPSD	ICGC;COSMIC	20.789	Gain
AGC_DMPK_ROCK_ROCK2_ST	O95644	NFATC1	O75116	ROCK2	S241	A244T	244	Missense	distal	3	no	29.014	27.642	PhosphoSitePlus	ICGC;COSMIC	20.789	Down-regulation
AGC_DMPK_ROCK_ROCK2_ST	O95644	NFATC1	O75116	ROCK2	S241	V246L	246	Missense	distal	5	no	29.014	28.010	PhosphoSitePlus	ICGC;COSMIC	20.789	Down-regulation
AGC_DMPK_ROCK_ROCK2_ST	O95644	NFATC1	O75116	ROCK2	S241	P242S	242	Missense	proximal	1	no	29.014	29.062	PhosphoSitePlus	ICGC;COSMIC	20.789	Up-regulation
AGC_DMPK_ROCK_ROCK2_ST	O95644	NFATC1	O75116	ROCK2	S241	V246I	246	Missense	distal	5	no	29.014	28.670	PhosphoSitePlus	ICGC;COSMIC	20.789	Down-regulation
AGC_DMPK_ROCK_ROCK2_ST	O95644	NFATC1	O75116	ROCK2	S241	P242L	242	Missense	proximal	1	no	29.014	29.080	PhosphoSitePlus	ICGC;COSMIC	20.789	Up-regulation
AGC_DMPK_ROCK_ROCK2_ST	O95644	NFATC1	O75116	ROCK2	S241	P234L	234	Missense	distal	-7	no	29.014	29.034	PhosphoSitePlus	ICGC;COSMIC	20.789	Up-regulation
AGC_DMPK_ROCK_ROCK2_ST	O95644	NFATC1	O75116	ROCK2	S245	E249D	249	Missense	distal	4	no	20.432	21.566	EPSD	ICGC;COSMIC	20.789	Gain
AGC_DMPK_ROCK_ROCK2_ST	O95644	NFATC1	O75116	ROCK2	S257	P262L	262	Missense	distal	5	no	20.848	20.388	EPSD	ICGC;COSMIC	20.789	Loss
AGC_DMPK_ROCK_ROCK2_ST	O95644	NFATC1	O75116	ROCK2	T339	S345L	345	Missense	distal	6	no	26.197	26.845	EPSD	ICGC;COSMIC	20.789	Up-regulation
AGC_DMPK_ROCK_ROCK2_ST	O95644	NFATC1	O75116	ROCK2	T339	E341D	341	Missense	proximal	2	no	26.197	26.053	EPSD	ICGC	20.789	Down-regulation
AGC_DMPK_ROCK_ROCK2_ST	O95644	NFATC1	O75116	ROCK2	T339	P332S	332	Missense	distal	-7	no	26.197	25.591	EPSD	ICGC;COSMIC	20.789	Down-regulation
AGC_DMPK_ROCK_ROCK2_ST	O95644	NFATC1	O75116	ROCK2	T339	R336S	336	Missense	distal	-3	no	26.197	12.293	EPSD	ICGC;COSMIC	20.789	Loss
AGC_DMPK_ROCK_ROCK2_ST	O95644	NFATC1	O75116	ROCK2	S406	P410T	410	Missense	distal	4	no	22.810	22.770	EPSD	ICGC;COSMIC	20.789	Down-regulation
AGC_DMPK_ROCK_ROCK2_ST	O95644	NFATC1	O75116	ROCK2	S406	P404S	404	Missense	proximal	-2	no	22.810	22.841	EPSD	ICGC;COSMIC	20.789	Up-regulation
AGC_DMPK_ROCK_ROCK2_ST	O95644	NFATC1	O75116	ROCK2	S406	P413S	413	Missense	distal	7	no	22.810	21.544	EPSD	ICGC;COSMIC	20.789	Down-regulation
AGC_DMPK_ROCK_ROCK2_ST	O95644	NFATC1	O75116	ROCK2	S406	S409R	409	Missense	distal	3	no	22.810	21.459	EPSD	ICGC;COSMIC	20.789	Down-regulation
AGC_DMPK_ROCK_ROCK2_ST	O95644	NFATC1	O75116	ROCK2	S503	S506N	506	Missense	distal	3	no	21.429	22.440	EPSD	ICGC	20.789	Up-regulation
AGC_DMPK_ROCK_ROCK2_ST	O95644	NFATC1	O75116	ROCK2	S503	V502L	502	Missense	proximal	-1	no	21.429	21.844	EPSD	ICGC	20.789	Up-regulation
AGC_DMPK_ROCK_ROCK2_ST	O95644	NFATC1	O75116	ROCK2	S503	G499W	499	Missense	distal	-4	no	21.429	20.277	EPSD	ICGC;COSMIC	20.789	Loss
AGC_DMPK_ROCK_ROCK2_ST	O95644	NFATC1	O75116	ROCK2	S503	E508K	508	Missense	distal	5	no	21.429	20.003	EPSD	ICGC;COSMIC	20.789	Loss
AGC_DMPK_ROCK_ROCK2_ST	O95644	NFATC1	O75116	ROCK2	S670	R667S	667	Missense	distal	-3	no	26.593	12.689	EPSD	ICGC;COSMIC	20.789	Loss
AGC_DMPK_ROCK_ROCK2_ST	O95644	NFATC1	O75116	ROCK2	S670	V674I	674	Missense	distal	4	no	26.593	27.177	EPSD	ICGC;COSMIC	20.789	Up-regulation
AGC_DMPK_ROCK_ROCK2_ST	O95644	NFATC1	O75116	ROCK2	S670	V672F	672	Missense	proximal	2	no	26.593	26.699	EPSD	ICGC;COSMIC	20.789	Up-regulation
AGC_DMPK_ROCK_ROCK2_ST	O95644	NFATC1	O75116	ROCK2	S670	V674F	674	Missense	distal	4	no	26.593	26.939	EPSD	ICGC;COSMIC	20.789	Up-regulation
AGC_DMPK_ROCK_ROCK2_ST	O95644	NFATC1	O75116	ROCK2	S670	S670N	670	Missense	central	0	yes	26.593	0.000	EPSD	ICGC;COSMIC	20.789	Loss
AGC_DMPK_ROCK_ROCK2_ST	Q96A00	PPP1R14A	O75116	ROCK2	S18	R21C	21	Missense	distal	3	no	29.775	30.506	EPSD	ICGC;COSMIC	20.789	Up-regulation
AGC_DMPK_ROCK_ROCK2_ST	Q96A00	PPP1R14A	O75116	ROCK2	T38	Q31K	31	Missense	distal	-7	no	34.400	34.311	PhosphoSitePlus	ICGC	20.789	Down-regulation
AGC_DMPK_ROCK_ROCK2_ST	Q96A00	PPP1R14A	O75116	ROCK2	T38	H34Y	34	Missense	distal	-4	no	34.400	37.240	PhosphoSitePlus	ICGC;COSMIC	20.789	Up-regulation
AGC_DMPK_ROCK_ROCK2_ST	Q96A00	PPP1R14A	O75116	ROCK2	T38	H34Q	34	Missense	distal	-4	no	34.400	35.591	PhosphoSitePlus	ICGC	20.789	Up-regulation
AGC_DMPK_ROCK_ROCK2_ST	Q96A00	PPP1R14A	O75116	ROCK2	T38	A35T	35	Missense	distal	-3	no	34.400	36.576	PhosphoSitePlus	ICGC;COSMIC	20.789	Up-regulation
AGC_DMPK_ROCK_ROCK2_ST	O75116	ROCK2	O75116	ROCK2	T7	G12S	12	Missense	distal	5	no	31.941	31.627	EPSD	ICGC;COSMIC	20.789	Down-regulation
AGC_DMPK_ROCK_ROCK2_ST	O75116	ROCK2	O75116	ROCK2	T16	G12S	12	Missense	distal	-4	no	23.398	22.884	EPSD	ICGC;COSMIC	20.789	Down-regulation
AGC_DMPK_ROCK_ROCK2_ST	P98082	DAB2	O75116	ROCK2	S24	A19S	19	Missense	distal	-5	no	22.148	21.903	EPSD	ICGC	20.789	Down-regulation
AGC_DMPK_ROCK_ROCK2_ST	Q99962	SH3GL2	O75116	ROCK2	T14	E19V	19	Missense	distal	5	no	41.153	41.431	PhosphoSitePlus	ICGC;COSMIC	20.789	Up-regulation
AGC_DMPK_ROCK_ROCK2_ST	Q99962	SH3GL2	O75116	ROCK2	T14	E19G	19	Missense	distal	5	no	41.153	41.108	PhosphoSitePlus	ICGC	20.789	Down-regulation
AGC_DMPK_ROCK_ROCK2_ST	Q99962	SH3GL2	O75116	ROCK2	S262	D269E	269	Missense	distal	7	no	23.343	22.769	EPSD	ICGC;COSMIC	20.789	Down-regulation
AGC_DMPK_ROCK_ROCK2_ST	P05067	APP	O75116	ROCK2	S348	S343R	343	Missense	distal	-5	no	21.197	23.801	EPSD	ICGC	20.789	Up-regulation
AGC_DMPK_ROCK_ROCK2_ST	P05067	APP	O75116	ROCK2	S679	A673E	673	Missense	distal	-6	no	23.926	20.485	EPSD	ICGC;COSMIC	20.789	Loss
AGC_DMPK_ROCK_ROCK2_ST	Q15417	CNN3	O75116	ROCK2	S9	P8T	8	Missense	proximal	-1	no	32.433	32.266	EPSD	ICGC;COSMIC	20.789	Down-regulation
AGC_DMPK_ROCK_ROCK2_ST	Q15417	CNN3	O75116	ROCK2	S13	P8T	8	Missense	distal	-5	no	22.017	22.906	EPSD	ICGC;COSMIC	20.789	Up-regulation
AGC_DMPK_ROCK_ROCK2_ST	Q15417	CNN3	O75116	ROCK2	T170	S175R	175	Missense	distal	5	no	27.004	26.983	EPSD	ICGC	20.789	Down-regulation
AGC_DMPK_ROCK_ROCK2_ST	Q15417	CNN3	O75116	ROCK2	T180	G183V	183	Missense	distal	3	no	25.595	25.694	EPSD	ICGC;COSMIC	20.789	Up-regulation
AGC_DMPK_ROCK_ROCK2_ST	Q15417	CNN3	O75116	ROCK2	T180	S175R	175	Missense	distal	-5	no	25.595	28.199	EPSD	ICGC	20.789	Up-regulation
AGC_DMPK_ROCK_ROCK2_ST	Q15417	CNN3	O75116	ROCK2	T184	G183V	183	Missense	proximal	-1	no	29.220	28.621	EPSD	ICGC;COSMIC	20.789	Down-regulation
AGC_DMPK_ROCK_ROCK2_ST	Q15417	CNN3	O75116	ROCK2	S259	Q266K	266	Missense	distal	7	no	23.547	22.755	EPSD	ICGC	20.789	Down-regulation
AGC_DMPK_ROCK_ROCK2_ST	Q15417	CNN3	O75116	ROCK2	T288	T288K	288	Missense	central	0	yes	29.655	0.000	EPSD	ICGC;COSMIC	20.789	Loss
AGC_DMPK_ROCK_ROCK2_ST	Q15417	CNN3	O75116	ROCK2	S293	T288K	288	Missense	distal	-5	no	38.489	39.116	PhosphoSitePlus	ICGC;COSMIC	20.789	Up-regulation
AGC_DMPK_ROCK_ROCK2_ST	Q15417	CNN3	O75116	ROCK2	S293	D299Y	299	Missense	distal	6	no	38.489	38.847	PhosphoSitePlus	ICGC;COSMIC	20.789	Up-regulation
AGC_DMPK_ROCK_ROCK2_ST	Q15417	CNN3	O75116	ROCK2	S296	D299Y	299	Missense	distal	3	no	24.676	26.292	EPSD	ICGC;COSMIC	20.789	Up-regulation
AGC_DMPK_ROCK_ROCK2_ST	Q15417	CNN3	O75116	ROCK2	S323	S323R	323	Missense	central	0	yes	23.116	0.000	EPSD	ICGC;COSMIC	20.789	Loss
AGC_DMPK_ROCK_ROCK2_ST	Q15417	CNN3	O75116	ROCK2	S323	D319H	319	Missense	distal	-4	no	23.116	21.026	EPSD	ICGC;COSMIC	20.789	Down-regulation
AGC_DMPK_ROCK_ROCK2_ST	Q96C90	PPP1R14B	O75116	ROCK2	T57	R52S	52	Missense	distal	-5	no	31.042	28.438	PhosphoSitePlus	ICGC	20.789	Down-regulation
AGC_DMPK_ROCK_ROCK2_ST	P68104	EEF1A1	O75116	ROCK2	T6	I10F	10	Missense	distal	4	no	30.320	30.082	EPSD	ICGC	20.789	Down-regulation
AGC_DMPK_ROCK_ROCK2_ST	P68104	EEF1A1	O75116	ROCK2	S21	G19V	19	Missense	proximal	-2	no	24.313	7.842	EPSD	ICGC	20.789	Loss
AGC_DMPK_ROCK_ROCK2_ST	P68104	EEF1A1	O75116	ROCK2	S21	K20N	20	Missense	proximal	-1	no	24.313	24.588	EPSD	ICGC	20.789	Up-regulation
AGC_DMPK_ROCK_ROCK2_ST	P68104	EEF1A1	O75116	ROCK2	S21	H26L	26	Missense	distal	5	no	24.313	24.401	EPSD	ICGC	20.789	Up-regulation
AGC_DMPK_ROCK_ROCK2_ST	P68104	EEF1A1	O75116	ROCK2	T22	G19V	19	Missense	distal	-3	no	20.963	0.690	EPSD	ICGC	20.789	Loss
AGC_DMPK_ROCK_ROCK2_ST	P68104	EEF1A1	O75116	ROCK2	T22	K20N	20	Missense	proximal	-2	no	20.963	15.774	EPSD	ICGC	20.789	Loss
AGC_DMPK_ROCK_ROCK2_ST	P68104	EEF1A1	O75116	ROCK2	T22	H26L	26	Missense	distal	4	no	20.963	20.790	EPSD	ICGC	20.789	Down-regulation
AGC_DMPK_ROCK_ROCK2_ST	P68104	EEF1A1	O75116	ROCK2	T24	G19V	19	Missense	distal	-5	no	22.142	17.240	EPSD	ICGC	20.789	Loss
AGC_DMPK_ROCK_ROCK2_ST	P68104	EEF1A1	O75116	ROCK2	T24	K20N	20	Missense	distal	-4	no	22.142	21.544	EPSD	ICGC	20.789	Down-regulation
AGC_DMPK_ROCK_ROCK2_ST	P68104	EEF1A1	O75116	ROCK2	T24	H26L	26	Missense	proximal	2	no	22.142	22.184	EPSD	ICGC	20.789	Up-regulation
AGC_DMPK_ROCK_ROCK2_ST	P68104	EEF1A1	O75116	ROCK2	S383	K378T	378	Missense	distal	-5	no	27.210	26.583	EPSD	ICGC;COSMIC	20.789	Down-regulation
AGC_DMPK_ROCK_ROCK2_ST	P68104	EEF1A1	O75116	ROCK2	S383	R382C	382	Missense	proximal	-1	no	27.210	25.938	EPSD	ICGC;COSMIC;CCLE	20.789	Down-regulation
AGC_DMPK_ROCK_ROCK2_ST	P68104	EEF1A1	O75116	ROCK2	T432	R427H	427	Missense	distal	-5	no	35.861	34.783	PhosphoSitePlus	ICGC;COSMIC	20.789	Down-regulation
AGC_DMPK_ROCK_ROCK2_ST	P68104	EEF1A1	O75116	ROCK2	T432	T432A	432	Missense	central	0	yes	35.861	0.000	PhosphoSitePlus	ICGC;COSMIC	20.789	Loss
AGC_DMPK_ROCK_ROCK2_ST	O14974	PPP1R12A	O75116	ROCK2	S477	S478Y	478	Missense	proximal	1	no	22.795	22.736	EPSD	ICGC;COSMIC	20.789	Down-regulation
AGC_DMPK_ROCK_ROCK2_ST	O14974	PPP1R12A	O75116	ROCK2	S478	S478Y	478	Missense	central	0	yes	24.684	0.000	EPSD	ICGC;COSMIC	20.789	Loss
AGC_DMPK_ROCK_ROCK2_ST	O14974	PPP1R12A	O75116	ROCK2	S668	R666H	666	Missense	proximal	-2	no	21.836	13.063	EPSD	ICGC;COSMIC	20.789	Loss
AGC_DMPK_ROCK_ROCK2_ST	O14974	PPP1R12A	O75116	ROCK2	S668	R666C	666	Missense	proximal	-2	no	21.836	-1.568	EPSD	ICGC	20.789	Loss
AGC_DMPK_ROCK_ROCK2_ST	O14974	PPP1R12A	O75116	ROCK2	S790	M787I	787	Missense	distal	-3	no	22.316	12.821	EPSD	ICGC;COSMIC	20.789	Loss
AGC_DMPK_ROCK_ROCK2_ST	O14974	PPP1R12A	O75116	ROCK2	S852	R850K	850	Missense	proximal	-2	no	31.029	22.076	EPSD	ICGC	20.789	Down-regulation
AGC_DMPK_ROCK_ROCK2_ST	O14974	PPP1R12A	O75116	ROCK2	S852	R845Q	845	Missense	distal	-7	no	31.029	31.532	EPSD	ICGC	20.789	Up-regulation
AGC_DMPK_ROCK_ROCK2_ST	O14974	PPP1R12A	O75116	ROCK2	T853	R850K	850	Missense	distal	-3	no	31.689	23.701	EPSD	ICGC	20.789	Down-regulation
AGC_DMPK_ROCK_ROCK2_ST	O14974	PPP1R12A	O75116	ROCK2	S856	R850K	850	Missense	distal	-6	no	21.083	20.785	EPSD	ICGC	20.789	Loss
AGC_DMPK_ROCK_ROCK2_ST	O14974	PPP1R12A	O75116	ROCK2	T892	S896L	896	Missense	distal	4	no	31.348	31.686	EPSD	ICGC	20.789	Up-regulation
AGC_DMPK_ROCK_ROCK2_ST	O14974	PPP1R12A	O75116	ROCK2	S912	G909R	909	Missense	distal	-3	no	18.074	26.258	EPSD	ICGC;COSMIC	20.789	Gain
STE_STE-Unique_MAP3K14_ST	P61160	ACTR2	Q99558	MAP3K14	T110	K106N	106	Missense	distal	-4	no	220.276	218.296	EPSD	ICGC;COSMIC	201.043	Down-regulation
STE_STE-Unique_MAP3K14_ST	P61160	ACTR2	Q99558	MAP3K14	T110	L108V	108	Missense	proximal	-2	no	220.276	225.256	EPSD	ICGC;COSMIC	201.043	Up-regulation
STE_STE-Unique_MAP3K14_ST	P61160	ACTR2	Q99558	MAP3K14	T110	P113L	113	Missense	distal	3	no	220.276	222.737	EPSD	ICGC	201.043	Up-regulation
STE_STE-Unique_MAP3K14_ST	P61160	ACTR2	Q99558	MAP3K14	T110	P113H	113	Missense	distal	3	no	220.276	221.653	EPSD	ICGC;COSMIC	201.043	Up-regulation
STE_STE-Unique_MAP3K14_ST	P61160	ACTR2	Q99558	MAP3K14	T110	R103S	103	Missense	distal	-7	no	220.276	215.501	EPSD	ICGC	201.043	Down-regulation
STE_STE-Unique_MAP3K14_ST	P61160	ACTR2	Q99558	MAP3K14	T237	S243Y	243	Missense	distal	6	no	357.311	352.185	EPSD;PhosphoSitePlus	ICGC;COSMIC	201.043	Down-regulation
STE_STE-Unique_MAP3K14_ST	P61160	ACTR2	Q99558	MAP3K14	T237	T237I	237	Missense	central	0	yes	357.311	0.000	EPSD;PhosphoSitePlus	ICGC	201.043	Loss
STE_STE-Unique_MAP3K14_ST	P61160	ACTR2	Q99558	MAP3K14	T238	S243Y	243	Missense	distal	5	no	362.511	362.557	PhosphoSitePlus;EPSD	ICGC;COSMIC	201.043	Up-regulation
STE_STE-Unique_MAP3K14_ST	P61160	ACTR2	Q99558	MAP3K14	T238	T237I	237	Missense	proximal	-1	no	362.511	352.474	PhosphoSitePlus;EPSD	ICGC	201.043	Down-regulation
STE_STE-Unique_MAP3K14_ST	P25963	NFKBIA	Q99558	MAP3K14	S32	R29S	29	Missense	distal	-3	no	360.434	360.621	EPSD;PhosphoSitePlus	ICGC	201.043	Up-regulation
STE_STE-Unique_MAP3K14_ST	P25963	NFKBIA	Q99558	MAP3K14	S32	D31G	31	Missense	proximal	-1	no	360.434	362.072	EPSD;PhosphoSitePlus	ICGC;COSMIC	201.043	Up-regulation
STE_STE-Unique_MAP3K14_ST	P25963	NFKBIA	Q99558	MAP3K14	S32	K38T	38	Missense	distal	6	no	360.434	356.375	EPSD;PhosphoSitePlus	ICGC	201.043	Down-regulation
STE_STE-Unique_MAP3K14_ST	P25963	NFKBIA	Q99558	MAP3K14	S36	R29S	29	Missense	distal	-7	no	397.236	392.460	PhosphoSitePlus;EPSD	ICGC	201.043	Down-regulation
STE_STE-Unique_MAP3K14_ST	P25963	NFKBIA	Q99558	MAP3K14	S36	D31G	31	Missense	distal	-5	no	397.236	383.837	PhosphoSitePlus;EPSD	ICGC;COSMIC	201.043	Down-regulation
STE_STE-Unique_MAP3K14_ST	P25963	NFKBIA	Q99558	MAP3K14	S36	K38T	38	Missense	proximal	2	no	397.236	395.218	PhosphoSitePlus;EPSD	ICGC	201.043	Down-regulation
STE_STE-Unique_MAP3K14_ST	O15111	CHUK	Q99558	MAP3K14	S123	G129W	129	Missense	distal	6	no	241.494	227.139	EPSD	ICGC;COSMIC	201.043	Down-regulation
STE_STE-Unique_MAP3K14_ST	O15111	CHUK	Q99558	MAP3K14	S581	T584K	584	Missense	distal	3	no	225.742	225.839	EPSD	ICGC;COSMIC	201.043	Up-regulation
STE_STE-Unique_MAP3K14_ST	O14920	IKBKB	Q99558	MAP3K14	S550	Q548L	548	Missense	proximal	-2	no	251.826	232.223	EPSD	ICGC;COSMIC	201.043	Down-regulation
STE_STE-Unique_MAP3K14_ST	O14920	IKBKB	Q99558	MAP3K14	S550	G557A	557	Missense	distal	7	no	251.826	245.804	EPSD	ICGC;COSMIC	201.043	Down-regulation
STE_STE-Unique_MAP3K14_ST	O14920	IKBKB	Q99558	MAP3K14	T583	P578L	578	Missense	distal	-5	no	216.886	220.040	EPSD	ICGC	201.043	Up-regulation
STE_STE-Unique_MAP3K14_ST	O14920	IKBKB	Q99558	MAP3K14	T583	P578V	578	Missense	distal	-5	no	216.886	210.647	EPSD	ICGC	201.043	Down-regulation
STE_STE-Unique_MAP3K14_ST	O14920	IKBKB	Q99558	MAP3K14	T583	P578A	578	Missense	distal	-5	no	216.886	213.673	EPSD	ICGC	201.043	Down-regulation
STE_STE-Unique_MAP3K14_ST	Q00653	NFKB2	Q99558	MAP3K14	S161	R160C	160	Missense	proximal	-1	no	236.164	213.727	EPSD	ICGC;COSMIC	201.043	Down-regulation
STE_STE-Unique_MAP3K14_ST	Q00653	NFKB2	Q99558	MAP3K14	T167	R160C	160	Missense	distal	-7	no	208.081	199.960	EPSD	ICGC;COSMIC	201.043	Loss
STE_STE-Unique_MAP3K14_ST	Q00653	NFKB2	Q99558	MAP3K14	T167	A169V	169	Missense	proximal	2	no	208.081	206.790	EPSD	ICGC;COSMIC;GDSC;CCLE	201.043	Down-regulation
STE_STE-Unique_MAP3K14_ST	Q00653	NFKB2	Q99558	MAP3K14	T811	T806K	806	Missense	distal	-5	no	226.871	237.498	EPSD	ICGC;COSMIC	201.043	Up-regulation
STE_STE-Unique_MAP3K14_ST	Q00653	NFKB2	Q99558	MAP3K14	T811	R808Q	808	Missense	distal	-3	no	226.871	226.882	EPSD	ICGC	201.043	Up-regulation
AGC_RSK_RSKp70_RPS6KB1_ST	Q9BYV9	BACH2	P23443	RPS6KB1	S521	S524P	524	Missense	distal	3	no	40.367	37.827	PhosphoSitePlus	ICGC;COSMIC	24.279	Down-regulation
AGC_RSK_RSKp70_RPS6KB1_ST	Q9BYV9	BACH2	P23443	RPS6KB1	S521	S522F	522	Missense	proximal	1	no	40.367	41.915	PhosphoSitePlus	ICGC	24.279	Up-regulation
AGC_RSK_RSKp70_RPS6KB1_ST	Q9BYV9	BACH2	P23443	RPS6KB1	S521	Y528S	528	Missense	distal	7	no	40.367	41.065	PhosphoSitePlus	ICGC;COSMIC	24.279	Up-regulation
AGC_RSK_RSKp70_RPS6KB1_ST	Q9BYV9	BACH2	P23443	RPS6KB1	S525	S524P	524	Missense	proximal	-1	no	30.986	31.083	EPSD	ICGC;COSMIC	24.279	Up-regulation
AGC_RSK_RSKp70_RPS6KB1_ST	Q9BYV9	BACH2	P23443	RPS6KB1	S525	S522F	522	Missense	distal	-3	no	30.986	27.316	EPSD	ICGC	24.279	Down-regulation
AGC_RSK_RSKp70_RPS6KB1_ST	Q9BYV9	BACH2	P23443	RPS6KB1	S525	Y528S	528	Missense	distal	3	no	30.986	32.663	EPSD	ICGC;COSMIC	24.279	Up-regulation
AGC_RSK_RSKp70_RPS6KB1_ST	Q9BYV9	BACH2	P23443	RPS6KB1	S527	S524P	524	Missense	distal	-3	no	26.399	23.261	EPSD	ICGC;COSMIC	24.279	Loss
AGC_RSK_RSKp70_RPS6KB1_ST	Q9BYV9	BACH2	P23443	RPS6KB1	S527	S522F	522	Missense	distal	-5	no	26.399	20.627	EPSD	ICGC	24.279	Loss
AGC_RSK_RSKp70_RPS6KB1_ST	Q9BYV9	BACH2	P23443	RPS6KB1	S527	Y528S	528	Missense	proximal	1	no	26.399	25.035	EPSD	ICGC;COSMIC	24.279	Down-regulation
AGC_RSK_RSKp70_RPS6KB1_ST	P35568	IRS1	P23443	RPS6KB1	S270	R265H	265	Missense	distal	-5	no	44.958	42.103	EPSD;PhosphoSitePlus	ICGC	24.279	Down-regulation
AGC_RSK_RSKp70_RPS6KB1_ST	P35568	IRS1	P23443	RPS6KB1	S270	F264L	264	Missense	distal	-6	no	44.958	44.903	EPSD;PhosphoSitePlus	ICGC	24.279	Down-regulation
AGC_RSK_RSKp70_RPS6KB1_ST	P35568	IRS1	P23443	RPS6KB1	S270	S272P	272	Missense	proximal	2	no	44.958	42.605	EPSD;PhosphoSitePlus	ICGC	24.279	Down-regulation
AGC_RSK_RSKp70_RPS6KB1_ST	P35568	IRS1	P23443	RPS6KB1	S270	S268I	268	Missense	proximal	-2	no	44.958	46.020	EPSD;PhosphoSitePlus	ICGC;COSMIC	24.279	Up-regulation
AGC_RSK_RSKp70_RPS6KB1_ST	P35568	IRS1	P23443	RPS6KB1	S272	R265H	265	Missense	distal	-7	no	27.405	27.460	EPSD	ICGC	24.279	Up-regulation
AGC_RSK_RSKp70_RPS6KB1_ST	P35568	IRS1	P23443	RPS6KB1	S272	S272P	272	Missense	central	0	yes	27.405	0.000	EPSD	ICGC	24.279	Loss
AGC_RSK_RSKp70_RPS6KB1_ST	P35568	IRS1	P23443	RPS6KB1	S272	N278T	278	Missense	distal	6	no	27.405	28.930	EPSD	ICGC	24.279	Up-regulation
AGC_RSK_RSKp70_RPS6KB1_ST	P35568	IRS1	P23443	RPS6KB1	S272	S268I	268	Missense	distal	-4	no	27.405	26.543	EPSD	ICGC;COSMIC	24.279	Down-regulation
AGC_RSK_RSKp70_RPS6KB1_ST	P35568	IRS1	P23443	RPS6KB1	T305	T300P	300	Missense	distal	-5	no	28.306	27.434	EPSD	ICGC;COSMIC;GDSC	24.279	Down-regulation
AGC_RSK_RSKp70_RPS6KB1_ST	P35568	IRS1	P23443	RPS6KB1	S307	T300P	300	Missense	distal	-7	no	46.236	46.392	EPSD;PhosphoSitePlus	ICGC;COSMIC;GDSC	24.279	Up-regulation
AGC_RSK_RSKp70_RPS6KB1_ST	P35568	IRS1	P23443	RPS6KB1	S312	G319R	319	Missense	distal	7	no	35.163	35.007	EPSD	ICGC;COSMIC	24.279	Down-regulation
AGC_RSK_RSKp70_RPS6KB1_ST	P35568	IRS1	P23443	RPS6KB1	S330	G332S	332	Missense	proximal	2	no	34.184	35.993	EPSD	ICGC;COSMIC	24.279	Up-regulation
AGC_RSK_RSKp70_RPS6KB1_ST	P35568	IRS1	P23443	RPS6KB1	S341	S345N	345	Missense	distal	4	no	28.623	27.553	EPSD	ICGC	24.279	Down-regulation
AGC_RSK_RSKp70_RPS6KB1_ST	P35568	IRS1	P23443	RPS6KB1	S362	H355Q	355	Missense	distal	-7	no	27.313	27.328	EPSD	ICGC	24.279	Up-regulation
AGC_RSK_RSKp70_RPS6KB1_ST	P35568	IRS1	P23443	RPS6KB1	S362	L369H	369	Missense	distal	7	no	27.313	27.183	EPSD	ICGC;COSMIC	24.279	Down-regulation
AGC_RSK_RSKp70_RPS6KB1_ST	P35568	IRS1	P23443	RPS6KB1	S372	L369H	369	Missense	distal	-3	no	31.118	37.297	EPSD	ICGC;COSMIC	24.279	Up-regulation
AGC_RSK_RSKp70_RPS6KB1_ST	P35568	IRS1	P23443	RPS6KB1	S374	L369H	369	Missense	distal	-5	no	23.203	28.972	EPSD	ICGC;COSMIC	24.279	Gain
AGC_RSK_RSKp70_RPS6KB1_ST	P35568	IRS1	P23443	RPS6KB1	S391	P389T	389	Missense	proximal	-2	no	27.826	26.969	EPSD	ICGC	24.279	Down-regulation
AGC_RSK_RSKp70_RPS6KB1_ST	P35568	IRS1	P23443	RPS6KB1	S391	S393T	393	Missense	proximal	2	no	27.826	26.928	EPSD	ICGC;COSMIC	24.279	Down-regulation
AGC_RSK_RSKp70_RPS6KB1_ST	P35568	IRS1	P23443	RPS6KB1	S391	S396G	396	Missense	distal	5	no	27.826	26.689	EPSD	ICGC;CCLE	24.279	Down-regulation
AGC_RSK_RSKp70_RPS6KB1_ST	P35568	IRS1	P23443	RPS6KB1	S396	S402C	402	Missense	distal	6	no	26.269	25.266	EPSD	ICGC;COSMIC	24.279	Down-regulation
AGC_RSK_RSKp70_RPS6KB1_ST	P35568	IRS1	P23443	RPS6KB1	S396	P389T	389	Missense	distal	-7	no	26.269	26.113	EPSD	ICGC	24.279	Down-regulation
AGC_RSK_RSKp70_RPS6KB1_ST	P35568	IRS1	P23443	RPS6KB1	S396	S393T	393	Missense	distal	-3	no	26.269	25.801	EPSD	ICGC;COSMIC	24.279	Down-regulation
AGC_RSK_RSKp70_RPS6KB1_ST	P35568	IRS1	P23443	RPS6KB1	S396	S396G	396	Missense	central	0	yes	26.269	0.000	EPSD	ICGC;CCLE	24.279	Loss
AGC_RSK_RSKp70_RPS6KB1_ST	P35568	IRS1	P23443	RPS6KB1	S398	S402C	402	Missense	distal	4	no	27.473	25.622	EPSD	ICGC;COSMIC	24.279	Down-regulation
AGC_RSK_RSKp70_RPS6KB1_ST	P35568	IRS1	P23443	RPS6KB1	S398	S393T	393	Missense	distal	-5	no	27.473	25.406	EPSD	ICGC;COSMIC	24.279	Down-regulation
AGC_RSK_RSKp70_RPS6KB1_ST	P35568	IRS1	P23443	RPS6KB1	S398	S396G	396	Missense	proximal	-2	no	27.473	27.252	EPSD	ICGC;CCLE	24.279	Down-regulation
AGC_RSK_RSKp70_RPS6KB1_ST	P35568	IRS1	P23443	RPS6KB1	S402	S402C	402	Missense	central	0	yes	26.489	0.000	EPSD	ICGC;COSMIC	24.279	Loss
AGC_RSK_RSKp70_RPS6KB1_ST	P35568	IRS1	P23443	RPS6KB1	S402	S396G	396	Missense	distal	-6	no	26.489	26.525	EPSD	ICGC;CCLE	24.279	Up-regulation
AGC_RSK_RSKp70_RPS6KB1_ST	P35568	IRS1	P23443	RPS6KB1	S415	S412P	412	Missense	distal	-3	no	39.075	35.938	EPSD	ICGC	24.279	Down-regulation
AGC_RSK_RSKp70_RPS6KB1_ST	P35568	IRS1	P23443	RPS6KB1	S415	S421R	421	Missense	distal	6	no	39.075	38.498	EPSD	ICGC	24.279	Down-regulation
AGC_RSK_RSKp70_RPS6KB1_ST	P35568	IRS1	P23443	RPS6KB1	S415	A414D	414	Missense	proximal	-1	no	39.075	39.076	EPSD	ICGC	24.279	Up-regulation
AGC_RSK_RSKp70_RPS6KB1_ST	P35568	IRS1	P23443	RPS6KB1	S415	R411L	411	Missense	distal	-4	no	39.075	39.380	EPSD	ICGC;COSMIC	24.279	Up-regulation
AGC_RSK_RSKp70_RPS6KB1_ST	P35568	IRS1	P23443	RPS6KB1	S415	R410W	410	Missense	distal	-5	no	39.075	27.112	EPSD	ICGC	24.279	Down-regulation
AGC_RSK_RSKp70_RPS6KB1_ST	P35568	IRS1	P23443	RPS6KB1	S440	D437Y	437	Missense	distal	-3	no	26.414	21.028	EPSD	ICGC;COSMIC	24.279	Loss
AGC_RSK_RSKp70_RPS6KB1_ST	P35568	IRS1	P23443	RPS6KB1	S444	D437Y	437	Missense	distal	-7	no	29.880	29.933	EPSD	ICGC;COSMIC	24.279	Up-regulation
AGC_RSK_RSKp70_RPS6KB1_ST	P35568	IRS1	P23443	RPS6KB1	T498	R493C	493	Missense	distal	-5	no	28.427	19.195	EPSD	ICGC	24.279	Loss
AGC_RSK_RSKp70_RPS6KB1_ST	P35568	IRS1	P23443	RPS6KB1	T498	R493H	493	Missense	distal	-5	no	28.427	25.572	EPSD	ICGC	24.279	Down-regulation
AGC_RSK_RSKp70_RPS6KB1_ST	P35568	IRS1	P23443	RPS6KB1	T525	S531Y	531	Missense	distal	6	no	28.631	27.153	EPSD	ICGC	24.279	Down-regulation
AGC_RSK_RSKp70_RPS6KB1_ST	P35568	IRS1	P23443	RPS6KB1	S527	S531Y	531	Missense	distal	4	no	36.607	35.217	EPSD;PhosphoSitePlus	ICGC	24.279	Down-regulation
AGC_RSK_RSKp70_RPS6KB1_ST	P35568	IRS1	P23443	RPS6KB1	S603	R600H	600	Missense	distal	-3	no	29.002	25.514	EPSD	ICGC;COSMIC	24.279	Down-regulation
AGC_RSK_RSKp70_RPS6KB1_ST	P35568	IRS1	P23443	RPS6KB1	S604	R600H	600	Missense	distal	-4	no	24.894	24.439	EPSD	ICGC;COSMIC	24.279	Down-regulation
AGC_RSK_RSKp70_RPS6KB1_ST	P35568	IRS1	P23443	RPS6KB1	T605	R600H	600	Missense	distal	-5	no	27.836	24.981	EPSD	ICGC;COSMIC	24.279	Down-regulation
AGC_RSK_RSKp70_RPS6KB1_ST	P35568	IRS1	P23443	RPS6KB1	S636	P634S	634	Missense	proximal	-2	no	36.942	35.035	PhosphoSitePlus;EPSD	ICGC;COSMIC	24.279	Down-regulation
AGC_RSK_RSKp70_RPS6KB1_ST	P35568	IRS1	P23443	RPS6KB1	S636	Y632C	632	Missense	distal	-4	no	36.942	35.514	PhosphoSitePlus;EPSD	ICGC;COSMIC	24.279	Down-regulation
AGC_RSK_RSKp70_RPS6KB1_ST	P35568	IRS1	P23443	RPS6KB1	S639	P634S	634	Missense	distal	-5	no	35.291	38.229	EPSD	ICGC;COSMIC	24.279	Up-regulation
AGC_RSK_RSKp70_RPS6KB1_ST	P35568	IRS1	P23443	RPS6KB1	S639	Y632C	632	Missense	distal	-7	no	35.291	35.186	EPSD	ICGC;COSMIC	24.279	Down-regulation
AGC_RSK_RSKp70_RPS6KB1_ST	P35568	IRS1	P23443	RPS6KB1	S668	D674A	674	Missense	distal	6	no	24.578	24.775	EPSD	ICGC	24.279	Up-regulation
AGC_RSK_RSKp70_RPS6KB1_ST	P35568	IRS1	P23443	RPS6KB1	S668	P667H	667	Missense	proximal	-1	no	24.578	24.528	EPSD	ICGC;COSMIC	24.279	Down-regulation
AGC_RSK_RSKp70_RPS6KB1_ST	P35568	IRS1	P23443	RPS6KB1	S672	D674A	674	Missense	proximal	2	no	24.150	24.785	EPSD	ICGC	24.279	Gain
AGC_RSK_RSKp70_RPS6KB1_ST	P35568	IRS1	P23443	RPS6KB1	S672	P667H	667	Missense	distal	-5	no	24.150	29.774	EPSD	ICGC;COSMIC	24.279	Gain
AGC_RSK_RSKp70_RPS6KB1_ST	P35568	IRS1	P23443	RPS6KB1	S680	G678V	678	Missense	proximal	-2	no	22.867	24.740	EPSD	ICGC;COSMIC	24.279	Gain
AGC_RSK_RSKp70_RPS6KB1_ST	P35568	IRS1	P23443	RPS6KB1	S680	S681C	681	Missense	proximal	1	no	22.867	24.604	EPSD	ICGC;COSMIC	24.279	Gain
AGC_RSK_RSKp70_RPS6KB1_ST	P35568	IRS1	P23443	RPS6KB1	S745	G752S	752	Missense	distal	7	no	23.990	24.369	EPSD	ICGC;COSMIC	24.279	Gain
AGC_RSK_RSKp70_RPS6KB1_ST	P35568	IRS1	P23443	RPS6KB1	S745	D748N	748	Missense	distal	3	no	23.990	24.510	EPSD	ICGC	24.279	Gain
AGC_RSK_RSKp70_RPS6KB1_ST	P35568	IRS1	P23443	RPS6KB1	T793	T793A	793	Missense	central	0	yes	26.941	0.000	EPSD	ICGC;COSMIC	24.279	Loss
AGC_RSK_RSKp70_RPS6KB1_ST	P35568	IRS1	P23443	RPS6KB1	T793	Y800C	800	Missense	distal	7	no	26.941	26.105	EPSD	ICGC;COSMIC	24.279	Down-regulation
AGC_RSK_RSKp70_RPS6KB1_ST	P35568	IRS1	P23443	RPS6KB1	T793	R790H	790	Missense	distal	-3	no	26.941	23.453	EPSD	ICGC	24.279	Loss
AGC_RSK_RSKp70_RPS6KB1_ST	P35568	IRS1	P23443	RPS6KB1	S974	G971R	971	Missense	distal	-3	no	18.539	26.364	EPSD	ICGC;COSMIC	24.279	Gain
AGC_RSK_RSKp70_RPS6KB1_ST	P35568	IRS1	P23443	RPS6KB1	S1101	S1106L	1106	Missense	distal	5	no	49.169	48.459	EPSD;PhosphoSitePlus	ICGC;COSMIC	24.279	Down-regulation
AGC_RSK_RSKp70_RPS6KB1_ST	P35568	IRS1	P23443	RPS6KB1	T1103	S1106L	1106	Missense	distal	3	no	30.220	28.520	EPSD	ICGC;COSMIC	24.279	Down-regulation
AGC_RSK_RSKp70_RPS6KB1_ST	P35568	IRS1	P23443	RPS6KB1	S1105	S1106L	1106	Missense	proximal	1	no	32.740	33.844	EPSD	ICGC;COSMIC	24.279	Up-regulation
AGC_RSK_RSKp70_RPS6KB1_ST	P35568	IRS1	P23443	RPS6KB1	S1105	R1112W	1112	Missense	distal	7	no	32.740	32.189	EPSD	ICGC;COSMIC	24.279	Down-regulation
AGC_RSK_RSKp70_RPS6KB1_ST	P35568	IRS1	P23443	RPS6KB1	S1105	R1112G	1112	Missense	distal	7	no	32.740	32.895	EPSD	ICGC;COSMIC	24.279	Up-regulation
AGC_RSK_RSKp70_RPS6KB1_ST	P35568	IRS1	P23443	RPS6KB1	S1106	S1106L	1106	Missense	central	0	yes	27.271	0.000	EPSD	ICGC;COSMIC	24.279	Loss
AGC_RSK_RSKp70_RPS6KB1_ST	P35568	IRS1	P23443	RPS6KB1	S1106	R1112W	1112	Missense	distal	6	no	27.271	26.629	EPSD	ICGC;COSMIC	24.279	Down-regulation
AGC_RSK_RSKp70_RPS6KB1_ST	P35568	IRS1	P23443	RPS6KB1	S1106	R1112G	1112	Missense	distal	6	no	27.271	28.014	EPSD	ICGC;COSMIC	24.279	Up-regulation
AGC_RSK_RSKp70_RPS6KB1_ST	P35568	IRS1	P23443	RPS6KB1	S1143	D1137N	1137	Missense	distal	-6	no	34.193	34.156	EPSD	ICGC	24.279	Down-regulation
AGC_RSK_RSKp70_RPS6KB1_ST	P35568	IRS1	P23443	RPS6KB1	S1216	L1211R	1211	Missense	distal	-5	no	23.886	32.511	EPSD	ICGC;COSMIC	24.279	Gain
AGC_RSK_RSKp70_RPS6KB1_ST	P42345	MTOR	P23443	RPS6KB1	T15	A9T	9	Missense	distal	-6	no	26.287	26.270	EPSD	ICGC;COSMIC	24.279	Down-regulation
AGC_RSK_RSKp70_RPS6KB1_ST	P42345	MTOR	P23443	RPS6KB1	T15	N18S	18	Missense	distal	3	no	26.287	27.125	EPSD	ICGC	24.279	Up-regulation
AGC_RSK_RSKp70_RPS6KB1_ST	P42345	MTOR	P23443	RPS6KB1	T15	S20R	20	Missense	distal	5	no	26.287	24.389	EPSD	ICGC	24.279	Down-regulation
AGC_RSK_RSKp70_RPS6KB1_ST	P42345	MTOR	P23443	RPS6KB1	T880	T880K	880	Missense	central	0	yes	25.228	0.000	EPSD	ICGC	24.279	Loss
AGC_RSK_RSKp70_RPS6KB1_ST	P42345	MTOR	P23443	RPS6KB1	T880	Q876K	876	Missense	distal	-4	no	25.228	28.193	EPSD	ICGC	24.279	Up-regulation
AGC_RSK_RSKp70_RPS6KB1_ST	P42345	MTOR	P23443	RPS6KB1	S1288	L1281M	1281	Missense	distal	-7	no	27.055	26.939	EPSD	ICGC;COSMIC	24.279	Down-regulation
AGC_RSK_RSKp70_RPS6KB1_ST	P42345	MTOR	P23443	RPS6KB1	S1288	L1284M	1284	Missense	distal	-4	no	27.055	27.718	EPSD	ICGC	24.279	Up-regulation
AGC_RSK_RSKp70_RPS6KB1_ST	P42345	MTOR	P23443	RPS6KB1	S1296	C1303F	1303	Missense	distal	7	no	27.084	26.738	EPSD	ICGC;COSMIC	24.279	Down-regulation
AGC_RSK_RSKp70_RPS6KB1_ST	P42345	MTOR	P23443	RPS6KB1	S1296	R1301L	1301	Missense	distal	5	no	27.084	28.271	EPSD	ICGC;COSMIC	24.279	Up-regulation
AGC_RSK_RSKp70_RPS6KB1_ST	P42345	MTOR	P23443	RPS6KB1	S1296	R1301H	1301	Missense	distal	5	no	27.084	27.384	EPSD	ICGC;COSMIC	24.279	Up-regulation
AGC_RSK_RSKp70_RPS6KB1_ST	P42345	MTOR	P23443	RPS6KB1	S1296	C1303R	1303	Missense	distal	7	no	27.084	28.085	EPSD	ICGC;COSMIC	24.279	Up-regulation
AGC_RSK_RSKp70_RPS6KB1_ST	P42345	MTOR	P23443	RPS6KB1	S1851	N1848K	1848	Missense	distal	-3	no	24.018	25.350	EPSD	ICGC	24.279	Gain
AGC_RSK_RSKp70_RPS6KB1_ST	P42345	MTOR	P23443	RPS6KB1	S1855	N1848K	1848	Missense	distal	-7	no	30.105	30.085	EPSD	ICGC	24.279	Down-regulation
AGC_RSK_RSKp70_RPS6KB1_ST	P42345	MTOR	P23443	RPS6KB1	S1893	S1893F	1893	Missense	central	0	yes	24.886	0.000	EPSD	ICGC	24.279	Loss
AGC_RSK_RSKp70_RPS6KB1_ST	P42345	MTOR	P23443	RPS6KB1	S1893	R1890S	1890	Missense	distal	-3	no	24.886	15.403	EPSD	ICGC;COSMIC	24.279	Loss
AGC_RSK_RSKp70_RPS6KB1_ST	P42345	MTOR	P23443	RPS6KB1	S2442	R2445S	2445	Missense	distal	3	no	23.375	24.943	EPSD	ICGC;COSMIC	24.279	Gain
AGC_RSK_RSKp70_RPS6KB1_ST	P42345	MTOR	P23443	RPS6KB1	T2446	R2445S	2445	Missense	proximal	-1	no	37.773	37.744	PhosphoSitePlus;EPSD	ICGC;COSMIC	24.279	Down-regulation
AGC_RSK_RSKp70_RPS6KB1_ST	P42345	MTOR	P23443	RPS6KB1	T2446	N2439S	2439	Missense	distal	-7	no	37.773	37.700	PhosphoSitePlus;EPSD	ICGC;COSMIC	24.279	Down-regulation
AGC_RSK_RSKp70_RPS6KB1_ST	P42345	MTOR	P23443	RPS6KB1	S2448	R2445S	2445	Missense	distal	-3	no	38.831	29.348	EPSD;PhosphoSitePlus	ICGC;COSMIC	24.279	Down-regulation
AGC_RSK_RSKp70_RPS6KB1_ST	P42345	MTOR	P23443	RPS6KB1	S2514	R2511Q	2511	Missense	distal	-3	no	25.147	6.091	EPSD	ICGC;COSMIC	24.279	Loss
AGC_RSK_RSKp70_RPS6KB1_ST	P42345	MTOR	P23443	RPS6KB1	S2514	G2510V	2510	Missense	distal	-4	no	25.147	26.083	EPSD	ICGC;COSMIC	24.279	Up-regulation
AGC_RSK_RSKp70_RPS6KB1_ST	P42345	MTOR	P23443	RPS6KB1	S2514	R2511L	2511	Missense	distal	-3	no	25.147	15.479	EPSD	ICGC;COSMIC	24.279	Loss
AGC_RSK_RSKp70_RPS6KB1_ST	P42345	MTOR	P23443	RPS6KB1	S2514	D2512G	2512	Missense	proximal	-2	no	25.147	23.256	EPSD	ICGC;COSMIC	24.279	Loss
AGC_RSK_RSKp70_RPS6KB1_ST	Q06787	FMR1	P23443	RPS6KB1	S191	T194I	194	Missense	distal	3	no	30.707	30.743	EPSD	ICGC;COSMIC	24.279	Up-regulation
AGC_RSK_RSKp70_RPS6KB1_ST	Q06787	FMR1	P23443	RPS6KB1	S191	R193C	193	Missense	proximal	2	no	30.707	30.025	EPSD	ICGC;COSMIC	24.279	Down-regulation
AGC_RSK_RSKp70_RPS6KB1_ST	Q06787	FMR1	P23443	RPS6KB1	S460	T463M	463	Missense	distal	3	no	28.019	29.091	EPSD	ICGC;COSMIC	24.279	Up-regulation
AGC_RSK_RSKp70_RPS6KB1_ST	Q06787	FMR1	P23443	RPS6KB1	S460	S460G	460	Missense	central	0	yes	28.019	0.000	EPSD	ICGC;COSMIC;GDSC;CCLE	24.279	Loss
AGC_RSK_RSKp70_RPS6KB1_ST	Q06787	FMR1	P23443	RPS6KB1	S500	E495K	495	Missense	distal	-5	no	34.017	32.825	PhosphoSitePlus	ICGC;COSMIC	24.279	Down-regulation
AGC_RSK_RSKp70_RPS6KB1_ST	Q06787	FMR1	P23443	RPS6KB1	S500	S500Y	500	Missense	central	0	yes	34.017	0.000	PhosphoSitePlus	ICGC;COSMIC	24.279	Loss
AGC_RSK_RSKp70_RPS6KB1_ST	Q06787	FMR1	P23443	RPS6KB1	S500	R507W	507	Missense	distal	7	no	34.017	33.466	PhosphoSitePlus	ICGC;COSMIC	24.279	Down-regulation
AGC_RSK_RSKp70_RPS6KB1_ST	Q06787	FMR1	P23443	RPS6KB1	S511	D508H	508	Missense	distal	-3	no	22.834	30.798	EPSD	ICGC	24.279	Gain
AGC_RSK_RSKp70_RPS6KB1_ST	Q9UN36	NDRG2	P23443	RPS6KB1	S332	R329C	329	Missense	distal	-3	no	41.835	32.286	EPSD;PhosphoSitePlus	ICGC	24.279	Down-regulation
AGC_RSK_RSKp70_RPS6KB1_ST	Q9UN36	NDRG2	P23443	RPS6KB1	S344	S346L	346	Missense	proximal	2	no	27.128	25.954	EPSD	ICGC;COSMIC	24.279	Down-regulation
AGC_RSK_RSKp70_RPS6KB1_ST	Q9UN36	NDRG2	P23443	RPS6KB1	S344	S344C	344	Missense	central	0	yes	27.128	0.000	EPSD	ICGC	24.279	Loss
AGC_RSK_RSKp70_RPS6KB1_ST	Q9UN36	NDRG2	P23443	RPS6KB1	S346	S346L	346	Missense	central	0	yes	30.746	0.000	EPSD	ICGC;COSMIC	24.279	Loss
AGC_RSK_RSKp70_RPS6KB1_ST	Q9UN36	NDRG2	P23443	RPS6KB1	S346	S344C	344	Missense	proximal	-2	no	30.746	32.986	EPSD	ICGC	24.279	Up-regulation
AGC_RSK_RSKp70_RPS6KB1_ST	Q9UN36	NDRG2	P23443	RPS6KB1	T348	S346L	346	Missense	proximal	-2	no	34.565	34.707	EPSD	ICGC;COSMIC	24.279	Up-regulation
AGC_RSK_RSKp70_RPS6KB1_ST	Q9UN36	NDRG2	P23443	RPS6KB1	T348	S344C	344	Missense	distal	-4	no	34.565	32.115	EPSD	ICGC	24.279	Down-regulation
AGC_RSK_RSKp70_RPS6KB1_ST	Q9UN36	NDRG2	P23443	RPS6KB1	S350	S346L	346	Missense	distal	-4	no	38.747	37.994	PhosphoSitePlus;EPSD	ICGC;COSMIC	24.279	Down-regulation
AGC_RSK_RSKp70_RPS6KB1_ST	Q9UN36	NDRG2	P23443	RPS6KB1	S350	S344C	344	Missense	distal	-6	no	38.747	38.793	PhosphoSitePlus;EPSD	ICGC	24.279	Up-regulation
AGC_RSK_RSKp70_RPS6KB1_ST	P62753	RPS6	P23443	RPS6KB1	T34	A33D	33	Missense	proximal	-1	no	35.593	35.594	EPSD	ICGC	24.279	Up-regulation
AGC_RSK_RSKp70_RPS6KB1_ST	P62753	RPS6	P23443	RPS6KB1	T34	R31C	31	Missense	distal	-3	no	35.593	26.044	EPSD	ICGC	24.279	Down-regulation
AGC_RSK_RSKp70_RPS6KB1_ST	P62753	RPS6	P23443	RPS6KB1	S235	A229S	229	Missense	distal	-6	no	33.709	33.673	EPSD;PhosphoSitePlus	ICGC;COSMIC	24.279	Down-regulation
AGC_RSK_RSKp70_RPS6KB1_ST	P62753	RPS6	P23443	RPS6KB1	S235	A229V	229	Missense	distal	-6	no	33.709	33.749	EPSD;PhosphoSitePlus	ICGC;COSMIC;GDSC;CCLE	24.279	Up-regulation
AGC_RSK_RSKp70_RPS6KB1_ST	P62753	RPS6	P23443	RPS6KB1	S236	A229S	229	Missense	distal	-7	no	44.462	44.315	EPSD;PhosphoSitePlus	ICGC;COSMIC	24.279	Down-regulation
AGC_RSK_RSKp70_RPS6KB1_ST	P62753	RPS6	P23443	RPS6KB1	S236	A229V	229	Missense	distal	-7	no	44.462	44.652	EPSD;PhosphoSitePlus	ICGC;COSMIC;GDSC;CCLE	24.279	Up-regulation
AGC_RSK_RSKp70_RPS6KB1_ST	P49841	GSK3B	P23443	RPS6KB1	T7	A11S	11	Missense	distal	4	no	27.025	27.528	EPSD	ICGC;COSMIC	24.279	Up-regulation
AGC_RSK_RSKp70_RPS6KB1_ST	P49841	GSK3B	P23443	RPS6KB1	S9	A11S	11	Missense	proximal	2	no	43.554	46.416	PhosphoSitePlus	ICGC;COSMIC	24.279	Up-regulation
AGC_RSK_RSKp70_RPS6KB1_ST	P49841	GSK3B	P23443	RPS6KB1	S13	A11S	11	Missense	proximal	-2	no	27.467	26.392	EPSD	ICGC;COSMIC	24.279	Down-regulation
AGC_RSK_RSKp70_RPS6KB1_ST	P49841	GSK3B	P23443	RPS6KB1	S29	D33E	33	Missense	distal	4	no	25.021	24.928	EPSD	ICGC	24.279	Down-regulation
AGC_RSK_RSKp70_RPS6KB1_ST	P49841	GSK3B	P23443	RPS6KB1	S35	D33E	33	Missense	proximal	-2	no	26.546	26.164	EPSD	ICGC	24.279	Down-regulation
AGC_RSK_RSKp70_RPS6KB1_ST	P49841	GSK3B	P23443	RPS6KB1	S55	Q52K	52	Missense	distal	-3	no	22.728	34.165	EPSD	ICGC	24.279	Gain
AGC_RSK_RSKp70_RPS6KB1_ST	P49841	GSK3B	P23443	RPS6KB1	T408	G406R	406	Missense	proximal	-2	no	24.977	25.843	EPSD	ICGC;COSMIC	24.279	Up-regulation
AGC_RSK_RSKp70_RPS6KB1_ST	P49841	GSK3B	P23443	RPS6KB1	T408	S415T	415	Missense	distal	7	no	24.977	24.312	EPSD	ICGC;COSMIC	24.279	Down-regulation
AGC_RSK_RSKp70_RPS6KB1_ST	P49841	GSK3B	P23443	RPS6KB1	S417	S415T	415	Missense	proximal	-2	no	26.957	28.007	EPSD	ICGC;COSMIC	24.279	Up-regulation
AGC_RSK_RSKp70_RPS6KB1_ST	Q53EL6	PDCD4	P23443	RPS6KB1	S67	R69L	69	Missense	proximal	2	no	38.492	39.420	PhosphoSitePlus;EPSD	ICGC	24.279	Up-regulation
AGC_RSK_RSKp70_RPS6KB1_ST	Q53EL6	PDCD4	P23443	RPS6KB1	S67	G72V	72	Missense	distal	5	no	38.492	37.237	PhosphoSitePlus;EPSD	ICGC	24.279	Down-regulation
AGC_RSK_RSKp70_RPS6KB1_ST	Q53EL6	PDCD4	P23443	RPS6KB1	S76	S82I	82	Missense	distal	6	no	35.747	34.623	EPSD	ICGC	24.279	Down-regulation
AGC_RSK_RSKp70_RPS6KB1_ST	Q53EL6	PDCD4	P23443	RPS6KB1	S76	S76L	76	Missense	central	0	yes	35.747	0.000	EPSD	ICGC;COSMIC	24.279	Loss
AGC_RSK_RSKp70_RPS6KB1_ST	Q53EL6	PDCD4	P23443	RPS6KB1	S76	R69L	69	Missense	distal	-7	no	35.747	35.852	EPSD	ICGC	24.279	Up-regulation
AGC_RSK_RSKp70_RPS6KB1_ST	Q53EL6	PDCD4	P23443	RPS6KB1	S76	G72V	72	Missense	distal	-4	no	35.747	36.683	EPSD	ICGC	24.279	Up-regulation
AGC_RSK_RSKp70_RPS6KB1_ST	Q53EL6	PDCD4	P23443	RPS6KB1	T234	C227F	227	Missense	distal	-7	no	25.863	26.061	EPSD	ICGC	24.279	Up-regulation
AGC_RSK_RSKp70_RPS6KB1_ST	Q53EL6	PDCD4	P23443	RPS6KB1	S313	W315C	315	Missense	proximal	2	no	25.958	27.968	EPSD	ICGC;COSMIC	24.279	Up-regulation
AGC_RSK_RSKp70_RPS6KB1_ST	Q53EL6	PDCD4	P23443	RPS6KB1	S313	G318V	318	Missense	distal	5	no	25.958	24.703	EPSD	ICGC;COSMIC	24.279	Down-regulation
AGC_RSK_RSKp70_RPS6KB1_ST	Q53EL6	PDCD4	P23443	RPS6KB1	S345	L340F	340	Missense	distal	-5	no	30.675	27.988	EPSD	ICGC	24.279	Down-regulation
AGC_RSK_RSKp70_RPS6KB1_ST	Q53EL6	PDCD4	P23443	RPS6KB1	S457	G451V	451	Missense	distal	-6	no	26.949	26.989	EPSD;PhosphoSitePlus	ICGC	24.279	Up-regulation
AGC_RSK_RSKp70_RPS6KB1_ST	Q53EL6	PDCD4	P23443	RPS6KB1	S457	E458G	458	Missense	proximal	1	no	26.949	26.879	EPSD;PhosphoSitePlus	ICGC;COSMIC	24.279	Down-regulation
AGC_RSK_RSKp70_RPS6KB1_ST	Q9H3D4	TP63	P23443	RPS6KB1	S395	R393C	393	Missense	proximal	-2	no	23.383	24.978	EPSD	ICGC;COSMIC	24.279	Gain
AGC_RSK_RSKp70_RPS6KB1_ST	P10636	MAPT	P23443	RPS6KB1	T17	A15T	15	Missense	proximal	-2	no	26.536	26.510	EPSD	ICGC;COSMIC	24.279	Down-regulation
AGC_RSK_RSKp70_RPS6KB1_ST	P10636	MAPT	P23443	RPS6KB1	T17	M11I	11	Missense	distal	-6	no	26.536	26.566	EPSD	ICGC	24.279	Up-regulation
AGC_RSK_RSKp70_RPS6KB1_ST	P10636	MAPT	P23443	RPS6KB1	S56	P59Q	59	Missense	distal	3	no	25.475	25.121	EPSD	ICGC	24.279	Down-regulation
AGC_RSK_RSKp70_RPS6KB1_ST	P10636	MAPT	P23443	RPS6KB1	S171	R164T	164	Missense	distal	-7	no	32.927	32.940	EPSD	ICGC;COSMIC	24.279	Up-regulation
AGC_RSK_RSKp70_RPS6KB1_ST	P10636	MAPT	P23443	RPS6KB1	S171	A166T	166	Missense	distal	-5	no	32.927	33.063	EPSD	ICGC	24.279	Up-regulation
AGC_RSK_RSKp70_RPS6KB1_ST	P10636	MAPT	P23443	RPS6KB1	S214	G208C	208	Missense	distal	-6	no	27.785	27.795	PhosphoSitePlus;EPSD	ICGC;COSMIC	24.279	Up-regulation
AGC_RSK_RSKp70_RPS6KB1_ST	P10636	MAPT	P23443	RPS6KB1	S214	R211S	211	Missense	distal	-3	no	27.785	18.301	PhosphoSitePlus;EPSD	ICGC;COSMIC	24.279	Loss
AGC_RSK_RSKp70_RPS6KB1_ST	P10636	MAPT	P23443	RPS6KB1	S214	G213E	213	Missense	proximal	-1	no	27.785	27.705	PhosphoSitePlus;EPSD	ICGC;COSMIC	24.279	Down-regulation
AGC_RSK_RSKp70_RPS6KB1_ST	P10636	MAPT	P23443	RPS6KB1	S227	P233H	233	Missense	distal	6	no	23.592	24.385	EPSD	ICGC;COSMIC	24.279	Gain
AGC_RSK_RSKp70_RPS6KB1_ST	P10636	MAPT	P23443	RPS6KB1	S238	P233H	233	Missense	distal	-5	no	22.027	27.650	EPSD	ICGC;COSMIC	24.279	Gain
AGC_RSK_RSKp70_RPS6KB1_ST	P10636	MAPT	P23443	RPS6KB1	S341	T346I	346	Missense	distal	5	no	38.788	36.582	EPSD	ICGC;COSMIC	24.279	Down-regulation
AGC_RSK_RSKp70_RPS6KB1_ST	P10636	MAPT	P23443	RPS6KB1	S341	A337V	337	Missense	distal	-4	no	38.788	37.800	EPSD	ICGC	24.279	Down-regulation
AGC_RSK_RSKp70_RPS6KB1_ST	P10636	MAPT	P23443	RPS6KB1	S341	D345E	345	Missense	distal	4	no	38.788	38.696	EPSD	ICGC;COSMIC	24.279	Down-regulation
AGC_RSK_RSKp70_RPS6KB1_ST	P10636	MAPT	P23443	RPS6KB1	S369	R364W	364	Missense	distal	-5	no	30.152	18.188	EPSD	ICGC;COSMIC	24.279	Loss
AGC_RSK_RSKp70_RPS6KB1_ST	P10636	MAPT	P23443	RPS6KB1	S369	P363L	363	Missense	distal	-6	no	30.152	30.145	EPSD	ICGC	24.279	Down-regulation
AGC_RSK_RSKp70_RPS6KB1_ST	P10636	MAPT	P23443	RPS6KB1	S447	Y441H	441	Missense	distal	-6	no	29.223	29.162	EPSD	ICGC;COSMIC	24.279	Down-regulation
AGC_RSK_RSKp70_RPS6KB1_ST	P10636	MAPT	P23443	RPS6KB1	S516	G521R	521	Missense	distal	5	no	24.626	23.865	EPSD	ICGC;COSMIC	24.279	Loss
AGC_RSK_RSKp70_RPS6KB1_ST	P10636	MAPT	P23443	RPS6KB1	S519	G521R	521	Missense	proximal	2	no	30.096	29.802	EPSD	ICGC;COSMIC	24.279	Down-regulation
AGC_RSK_RSKp70_RPS6KB1_ST	P10636	MAPT	P23443	RPS6KB1	T522	G521R	521	Missense	proximal	-1	no	25.064	25.007	EPSD	ICGC;COSMIC	24.279	Down-regulation
AGC_RSK_RSKp70_RPS6KB1_ST	P10636	MAPT	P23443	RPS6KB1	S525	G521R	521	Missense	distal	-4	no	28.457	30.446	EPSD	ICGC;COSMIC	24.279	Up-regulation
AGC_RSK_RSKp70_RPS6KB1_ST	Q92519	TRIB2	P23443	RPS6KB1	S83	H82Q	82	Missense	proximal	-1	no	35.522	35.532	PhosphoSitePlus	ICGC;COSMIC	24.279	Up-regulation
AGC_RSK_RSKp70_RPS6KB1_ST	Q8TB45	DEPTOR	P23443	RPS6KB1	T7	G8C	8	Missense	proximal	1	no	23.682	24.317	EPSD	ICGC	24.279	Gain
AGC_RSK_RSKp70_RPS6KB1_ST	Q8TB45	DEPTOR	P23443	RPS6KB1	T7	G5C	5	Missense	proximal	-2	no	23.682	26.143	EPSD	ICGC	24.279	Gain
AGC_RSK_RSKp70_RPS6KB1_ST	Q8TB45	DEPTOR	P23443	RPS6KB1	S12	G8C	8	Missense	distal	-4	no	25.663	26.260	EPSD	ICGC	24.279	Up-regulation
AGC_RSK_RSKp70_RPS6KB1_ST	Q8TB45	DEPTOR	P23443	RPS6KB1	S12	G5C	5	Missense	distal	-7	no	25.663	25.651	EPSD	ICGC	24.279	Down-regulation
AGC_RSK_RSKp70_RPS6KB1_ST	Q8TB45	DEPTOR	P23443	RPS6KB1	S14	G8C	8	Missense	distal	-6	no	29.224	29.235	EPSD	ICGC	24.279	Up-regulation
AGC_RSK_RSKp70_RPS6KB1_ST	Q8TB45	DEPTOR	P23443	RPS6KB1	S15	G8C	8	Missense	distal	-7	no	25.281	25.268	EPSD	ICGC	24.279	Down-regulation
AGC_RSK_RSKp70_RPS6KB1_ST	Q8TB45	DEPTOR	P23443	RPS6KB1	T59	R53S	53	Missense	distal	-6	no	33.863	33.856	EPSD	ICGC	24.279	Down-regulation
AGC_RSK_RSKp70_RPS6KB1_ST	Q8TB45	DEPTOR	P23443	RPS6KB1	T59	Y60F	60	Missense	proximal	1	no	33.863	34.048	EPSD	ICGC;COSMIC	24.279	Up-regulation
AGC_RSK_RSKp70_RPS6KB1_ST	P23443	RPS6KB1	P23443	RPS6KB1	S441	P445T	445	Missense	distal	4	no	31.447	31.631	EPSD	ICGC;COSMIC	24.279	Up-regulation
AGC_RSK_RSKp70_RPS6KB1_ST	P23443	RPS6KB1	P23443	RPS6KB1	S441	S441N	441	Missense	central	0	yes	31.447	0.000	EPSD	ICGC;COSMIC	24.279	Loss
AGC_RSK_RSKp70_RPS6KB1_ST	O00418	EEF2K	P23443	RPS6KB1	S66	S71F	71	Missense	distal	5	no	25.313	19.951	EPSD	ICGC;COSMIC	24.279	Loss
AGC_RSK_RSKp70_RPS6KB1_ST	O00418	EEF2K	P23443	RPS6KB1	S66	S66R	66	Missense	central	0	yes	25.313	0.000	EPSD	ICGC	24.279	Loss
AGC_RSK_RSKp70_RPS6KB1_ST	O00418	EEF2K	P23443	RPS6KB1	S71	P75A	75	Missense	distal	4	no	34.356	34.786	EPSD	ICGC;COSMIC	24.279	Up-regulation
AGC_RSK_RSKp70_RPS6KB1_ST	O00418	EEF2K	P23443	RPS6KB1	S71	P75L	75	Missense	distal	4	no	34.356	34.842	EPSD	ICGC;COSMIC	24.279	Up-regulation
AGC_RSK_RSKp70_RPS6KB1_ST	O00418	EEF2K	P23443	RPS6KB1	S71	S71F	71	Missense	central	0	yes	34.356	0.000	EPSD	ICGC;COSMIC	24.279	Loss
AGC_RSK_RSKp70_RPS6KB1_ST	O00418	EEF2K	P23443	RPS6KB1	S71	S66R	66	Missense	distal	-5	no	34.356	39.895	EPSD	ICGC	24.279	Up-regulation
AGC_RSK_RSKp70_RPS6KB1_ST	O00418	EEF2K	P23443	RPS6KB1	T364	Q361R	361	Missense	distal	-3	no	8.026	27.082	EPSD	ICGC	24.279	Gain
AGC_RSK_RSKp70_RPS6KB1_ST	O00418	EEF2K	P23443	RPS6KB1	S366	R369W	369	Missense	distal	3	no	37.526	35.899	PhosphoSitePlus	ICGC	24.279	Down-regulation
AGC_RSK_RSKp70_RPS6KB1_ST	O00418	EEF2K	P23443	RPS6KB1	S366	Q361R	361	Missense	distal	-5	no	37.526	49.501	PhosphoSitePlus	ICGC	24.279	Up-regulation
AGC_RSK_RSKp70_RPS6KB1_ST	O00418	EEF2K	P23443	RPS6KB1	S366	P360L	360	Missense	distal	-6	no	37.526	37.519	PhosphoSitePlus	ICGC	24.279	Down-regulation
AGC_RSK_RSKp70_RPS6KB1_ST	O00418	EEF2K	P23443	RPS6KB1	S404	S404C	404	Missense	central	0	yes	28.363	0.000	EPSD	ICGC	24.279	Loss
AGC_RSK_RSKp70_RPS6KB1_ST	O00418	EEF2K	P23443	RPS6KB1	S404	H411Y	411	Missense	distal	7	no	28.363	28.311	EPSD	ICGC;COSMIC	24.279	Down-regulation
AGC_RSK_RSKp70_RPS6KB1_ST	O00418	EEF2K	P23443	RPS6KB1	S416	A422S	422	Missense	distal	6	no	25.562	26.681	EPSD	ICGC	24.279	Up-regulation
AGC_RSK_RSKp70_RPS6KB1_ST	O00418	EEF2K	P23443	RPS6KB1	S416	H411Y	411	Missense	distal	-5	no	25.562	18.172	EPSD	ICGC;COSMIC	24.279	Loss
AGC_RSK_RSKp70_RPS6KB1_ST	O00418	EEF2K	P23443	RPS6KB1	S416	P413A	413	Missense	distal	-3	no	25.562	28.262	EPSD	ICGC;COSMIC	24.279	Up-regulation
AGC_RSK_RSKp70_RPS6KB1_ST	O00418	EEF2K	P23443	RPS6KB1	S435	E436D	436	Missense	proximal	1	no	26.043	25.399	EPSD	ICGC;COSMIC	24.279	Down-regulation
AGC_RSK_RSKp70_RPS6KB1_ST	O00418	EEF2K	P23443	RPS6KB1	S435	R433L	433	Missense	proximal	-2	no	26.043	25.540	EPSD	ICGC;COSMIC	24.279	Down-regulation
AGC_RSK_RSKp70_RPS6KB1_ST	O00418	EEF2K	P23443	RPS6KB1	S435	H432L	432	Missense	distal	-3	no	26.043	19.865	EPSD	ICGC	24.279	Loss
AGC_RSK_RSKp70_RPS6KB1_ST	O00418	EEF2K	P23443	RPS6KB1	S435	S438I	438	Missense	distal	3	no	26.043	24.233	EPSD	ICGC	24.279	Loss
AGC_RSK_RSKp70_RPS6KB1_ST	O00418	EEF2K	P23443	RPS6KB1	S438	E436D	436	Missense	proximal	-2	no	28.507	28.889	EPSD	ICGC;COSMIC	24.279	Up-regulation
AGC_RSK_RSKp70_RPS6KB1_ST	O00418	EEF2K	P23443	RPS6KB1	S438	R433L	433	Missense	distal	-5	no	28.507	19.883	EPSD	ICGC;COSMIC	24.279	Loss
AGC_RSK_RSKp70_RPS6KB1_ST	O00418	EEF2K	P23443	RPS6KB1	S438	H432L	432	Missense	distal	-6	no	28.507	28.530	EPSD	ICGC	24.279	Up-regulation
AGC_RSK_RSKp70_RPS6KB1_ST	O00418	EEF2K	P23443	RPS6KB1	S438	S438I	438	Missense	central	0	yes	28.507	0.000	EPSD	ICGC	24.279	Loss
AGC_RSK_RSKp70_RPS6KB1_ST	O00418	EEF2K	P23443	RPS6KB1	S445	R448L	448	Missense	distal	3	no	28.174	28.042	EPSD	ICGC;COSMIC	24.279	Down-regulation
AGC_RSK_RSKp70_RPS6KB1_ST	O00418	EEF2K	P23443	RPS6KB1	S445	S438I	438	Missense	distal	-7	no	28.174	28.354	EPSD	ICGC	24.279	Up-regulation
AGC_RSK_RSKp70_RPS6KB1_ST	O00418	EEF2K	P23443	RPS6KB1	S462	R466W	466	Missense	distal	4	no	31.229	30.433	EPSD	ICGC;COSMIC	24.279	Down-regulation
AGC_RSK_RSKp70_RPS6KB1_ST	O00418	EEF2K	P23443	RPS6KB1	S462	R457L	457	Missense	distal	-5	no	31.229	22.604	EPSD	ICGC	24.279	Loss
AGC_RSK_RSKp70_RPS6KB1_ST	O00418	EEF2K	P23443	RPS6KB1	S470	R466W	466	Missense	distal	-4	no	27.506	25.826	EPSD	ICGC;COSMIC	24.279	Down-regulation
AGC_RSK_RSKp70_RPS6KB1_ST	O00418	EEF2K	P23443	RPS6KB1	S470	D471Y	471	Missense	proximal	1	no	27.506	28.342	EPSD	ICGC	24.279	Up-regulation
AGC_RSK_RSKp70_RPS6KB1_ST	P03372	ESR1	P23443	RPS6KB1	S118	H112P	112	Missense	distal	-6	no	25.450	25.480	EPSD	ICGC;COSMIC	24.279	Up-regulation
AGC_RSK_RSKp70_RPS6KB1_ST	P03372	ESR1	P23443	RPS6KB1	S118	P114L	114	Missense	distal	-4	no	25.450	26.361	EPSD	ICGC;COSMIC	24.279	Up-regulation
AGC_RSK_RSKp70_RPS6KB1_ST	P03372	ESR1	P23443	RPS6KB1	S154	S154L	154	Missense	central	0	yes	24.680	0.000	EPSD	ICGC	24.279	Loss
AGC_RSK_RSKp70_RPS6KB1_ST	P03372	ESR1	P23443	RPS6KB1	S154	R158H	158	Missense	distal	4	no	24.680	24.743	EPSD	ICGC;COSMIC;CCLE	24.279	Up-regulation
AGC_RSK_RSKp70_RPS6KB1_ST	P03372	ESR1	P23443	RPS6KB1	S154	N153K	153	Missense	proximal	-1	no	24.680	24.677	EPSD	ICGC	24.279	Down-regulation
AGC_RSK_RSKp70_RPS6KB1_ST	P03372	ESR1	P23443	RPS6KB1	S154	P147L	147	Missense	distal	-7	no	24.680	24.616	EPSD	ICGC;COSMIC	24.279	Down-regulation
AGC_RSK_RSKp70_RPS6KB1_ST	P03372	ESR1	P23443	RPS6KB1	S167	E163Q	163	Missense	distal	-4	no	39.842	38.267	PhosphoSitePlus	ICGC;COSMIC	24.279	Down-regulation
AGC_RSK_RSKp70_RPS6KB1_ST	P03372	ESR1	P23443	RPS6KB1	S236	Q238R	238	Missense	proximal	2	no	28.484	30.292	EPSD	ICGC	24.279	Up-regulation
AGC_RSK_RSKp70_RPS6KB1_ST	P03372	ESR1	P23443	RPS6KB1	S236	L242I	242	Missense	distal	6	no	28.484	27.516	EPSD	ICGC	24.279	Down-regulation
AGC_RSK_RSKp70_RPS6KB1_ST	P03372	ESR1	P23443	RPS6KB1	S236	R233M	233	Missense	distal	-3	no	28.484	22.985	EPSD	ICGC;COSMIC	24.279	Loss
AGC_RSK_RSKp70_RPS6KB1_ST	P03372	ESR1	P23443	RPS6KB1	S282	A283V	283	Missense	proximal	1	no	25.502	26.555	EPSD	ICGC;COSMIC	24.279	Up-regulation
AGC_RSK_RSKp70_RPS6KB1_ST	P03372	ESR1	P23443	RPS6KB1	S341	S341L	341	Missense	central	0	yes	27.403	0.000	EPSD	ICGC;COSMIC;GDSC;CCLE	24.279	Loss
AGC_RSK_RSKp70_RPS6KB1_ST	P03372	ESR1	P23443	RPS6KB1	S341	P336A	336	Missense	distal	-5	no	27.403	28.140	EPSD	ICGC;COSMIC	24.279	Up-regulation
AGC_RSK_RSKp70_RPS6KB1_ST	P03372	ESR1	P23443	RPS6KB1	S559	R555L	555	Missense	distal	-4	no	25.754	26.058	EPSD	ICGC	24.279	Up-regulation
AGC_RSK_RSKp70_RPS6KB1_ST	Q16873	LTC4S	P23443	RPS6KB1	S36	G42D	42	Missense	distal	6	no	36.794	35.311	PhosphoSitePlus	ICGC;COSMIC	24.279	Down-regulation
AGC_RSK_RSKp70_RPS6KB1_ST	Q05195	MXD1	P23443	RPS6KB1	S32	A26S	26	Missense	distal	-6	no	24.498	24.462	EPSD	ICGC	24.279	Down-regulation
AGC_RSK_RSKp70_RPS6KB1_ST	Q05195	MXD1	P23443	RPS6KB1	S145	S145C	145	Missense	central	0	yes	38.496	0.000	PhosphoSitePlus	ICGC;COSMIC	24.279	Loss
AGC_RSK_RSKp70_RPS6KB1_ST	O94763	URI1	P23443	RPS6KB1	S359	E364K	364	Missense	distal	5	no	25.048	25.273	EPSD	ICGC;COSMIC	24.279	Up-regulation
AGC_RSK_RSKp70_RPS6KB1_ST	O94763	URI1	P23443	RPS6KB1	S372	A379S	379	Missense	distal	7	no	47.363	47.676	PhosphoSitePlus	ICGC	24.279	Up-regulation
AGC_RSK_RSKp70_RPS6KB1_ST	O94763	URI1	P23443	RPS6KB1	S372	G374C	374	Missense	proximal	2	no	47.363	46.387	PhosphoSitePlus	ICGC	24.279	Down-regulation
AGC_RSK_RSKp70_RPS6KB1_ST	O94763	URI1	P23443	RPS6KB1	T373	Q380R	380	Missense	distal	7	no	24.961	24.379	EPSD	ICGC	24.279	Down-regulation
AGC_RSK_RSKp70_RPS6KB1_ST	O94763	URI1	P23443	RPS6KB1	T373	A379S	379	Missense	distal	6	no	24.961	26.081	EPSD	ICGC	24.279	Up-regulation
AGC_RSK_RSKp70_RPS6KB1_ST	O94763	URI1	P23443	RPS6KB1	T373	G374C	374	Missense	proximal	1	no	24.961	25.596	EPSD	ICGC	24.279	Up-regulation
AGC_RSK_RSKp70_RPS6KB1_ST	O94763	URI1	P23443	RPS6KB1	S418	E425D	425	Missense	distal	7	no	33.719	32.866	EPSD	ICGC;COSMIC	24.279	Down-regulation
AGC_RSK_RSKp70_RPS6KB1_ST	O94763	URI1	P23443	RPS6KB1	S421	E425D	425	Missense	distal	4	no	25.761	25.854	EPSD	ICGC;COSMIC	24.279	Up-regulation
AGC_RSK_RSKp70_RPS6KB1_ST	O94763	URI1	P23443	RPS6KB1	S442	S440T	440	Missense	proximal	-2	no	27.609	28.659	EPSD	ICGC	24.279	Up-regulation
AGC_RSK_RSKp70_RPS6KB1_ST	O94763	URI1	P23443	RPS6KB1	S449	D450G	450	Missense	proximal	1	no	23.753	24.327	EPSD	ICGC;COSMIC	24.279	Gain
AGC_RSK_RSKp70_RPS6KB1_ST	O94763	URI1	P23443	RPS6KB1	S454	D450G	450	Missense	distal	-4	no	26.663	24.780	EPSD	ICGC;COSMIC	24.279	Down-regulation
AGC_RSK_RSKp70_RPS6KB1_ST	P27708	CAD	P23443	RPS6KB1	S1337	G1339V	1339	Missense	proximal	2	no	26.498	24.608	EPSD	ICGC	24.279	Down-regulation
AGC_RSK_RSKp70_RPS6KB1_ST	P27708	CAD	P23443	RPS6KB1	S1337	L1342F	1342	Missense	distal	5	no	26.498	21.845	EPSD	ICGC;COSMIC	24.279	Loss
AGC_RSK_RSKp70_RPS6KB1_ST	P27708	CAD	P23443	RPS6KB1	S1977	A1982G	1982	Missense	distal	5	no	30.294	30.885	EPSD	ICGC;COSMIC	24.279	Up-regulation
AGC_RSK_RSKp70_RPS6KB1_ST	P27708	CAD	P23443	RPS6KB1	S1978	A1982G	1982	Missense	distal	4	no	26.434	25.344	EPSD	ICGC;COSMIC	24.279	Down-regulation
AGC_RSK_RSKp70_RPS6KB1_ST	Q09161	NCBP1	P23443	RPS6KB1	S2	E9K	9	Missense	distal	7	no	24.947	24.975	EPSD	ICGC	24.279	Up-regulation
AGC_RSK_RSKp70_RPS6KB1_ST	Q09161	NCBP1	P23443	RPS6KB1	S2	R4W	4	Missense	proximal	2	no	24.947	22.255	EPSD	ICGC;COSMIC	24.279	Loss
AGC_RSK_RSKp70_RPS6KB1_ST	Q09161	NCBP1	P23443	RPS6KB1	S7	E9K	9	Missense	proximal	2	no	36.147	37.805	EPSD;PhosphoSitePlus	ICGC	24.279	Up-regulation
AGC_RSK_RSKp70_RPS6KB1_ST	Q09161	NCBP1	P23443	RPS6KB1	S7	R4W	4	Missense	distal	-3	no	36.147	21.131	EPSD;PhosphoSitePlus	ICGC;COSMIC	24.279	Loss
AGC_RSK_RSKp70_RPS6KB1_ST	Q09161	NCBP1	P23443	RPS6KB1	T295	V302F	302	Missense	distal	7	no	24.552	23.589	EPSD	ICGC;COSMIC	24.279	Loss
AGC_RSK_RSKp70_RPS6KB1_ST	Q09161	NCBP1	P23443	RPS6KB1	T295	P298H	298	Missense	distal	3	no	24.552	25.131	EPSD	ICGC;COSMIC	24.279	Up-regulation
AGC_RSK_RSKp70_RPS6KB1_ST	Q09161	NCBP1	P23443	RPS6KB1	S434	R427H	427	Missense	distal	-7	no	28.061	28.116	EPSD	ICGC;COSMIC	24.279	Up-regulation
AGC_RSK_RSKp70_RPS6KB1_ST	Q9GZT9	EGLN1	P23443	RPS6KB1	S38	S38R	38	Missense	central	0	yes	24.319	0.000	EPSD	ICGC;COSMIC	24.279	Loss
AGC_RSK_RSKp70_RPS6KB1_ST	Q9GZT9	EGLN1	P23443	RPS6KB1	T185	G178D	178	Missense	distal	-7	no	32.445	32.485	EPSD	ICGC	24.279	Up-regulation
AGC_RSK_RSKp70_RPS6KB1_ST	P78371	CCT2	P23443	RPS6KB1	T23	A24S	24	Missense	proximal	1	no	24.549	24.929	EPSD	ICGC;COSMIC	24.279	Up-regulation
AGC_RSK_RSKp70_RPS6KB1_ST	P78371	CCT2	P23443	RPS6KB1	T23	A24D	24	Missense	proximal	1	no	24.549	25.457	EPSD	ICGC;COSMIC	24.279	Up-regulation
AGC_RSK_RSKp70_RPS6KB1_ST	P78371	CCT2	P23443	RPS6KB1	S28	A32S	32	Missense	distal	4	no	24.842	25.345	EPSD	ICGC	24.279	Up-regulation
AGC_RSK_RSKp70_RPS6KB1_ST	P78371	CCT2	P23443	RPS6KB1	S28	A24S	24	Missense	distal	-4	no	24.842	25.965	EPSD	ICGC;COSMIC	24.279	Up-regulation
AGC_RSK_RSKp70_RPS6KB1_ST	P78371	CCT2	P23443	RPS6KB1	S28	A24D	24	Missense	distal	-4	no	24.842	24.801	EPSD	ICGC;COSMIC	24.279	Down-regulation
AGC_RSK_RSKp70_RPS6KB1_ST	P78371	CCT2	P23443	RPS6KB1	S55	R57L	57	Missense	proximal	2	no	23.943	24.871	EPSD	ICGC	24.279	Gain
AGC_RSK_RSKp70_RPS6KB1_ST	P78371	CCT2	P23443	RPS6KB1	S60	D66H	66	Missense	distal	6	no	30.634	31.769	EPSD	ICGC;COSMIC	24.279	Up-regulation
AGC_RSK_RSKp70_RPS6KB1_ST	P78371	CCT2	P23443	RPS6KB1	S60	R57L	57	Missense	distal	-3	no	30.634	20.967	EPSD	ICGC	24.279	Loss
AGC_RSK_RSKp70_RPS6KB1_ST	P78371	CCT2	P23443	RPS6KB1	S60	D58Y	58	Missense	proximal	-2	no	30.634	29.907	EPSD	ICGC;COSMIC	24.279	Down-regulation
AGC_RSK_RSKp70_RPS6KB1_ST	P78371	CCT2	P23443	RPS6KB1	S60	V63I	63	Missense	distal	3	no	30.634	30.890	EPSD	ICGC;COSMIC	24.279	Up-regulation
AGC_RSK_RSKp70_RPS6KB1_ST	P78371	CCT2	P23443	RPS6KB1	T99	A106S	106	Missense	distal	7	no	23.973	24.286	EPSD	ICGC	24.279	Gain
AGC_RSK_RSKp70_RPS6KB1_ST	P78371	CCT2	P23443	RPS6KB1	S101	A106S	106	Missense	distal	5	no	23.052	24.780	EPSD	ICGC	24.279	Gain
AGC_RSK_RSKp70_RPS6KB1_ST	P78371	CCT2	P23443	RPS6KB1	S115	A118V	118	Missense	distal	3	no	23.954	24.335	EPSD	ICGC;COSMIC	24.279	Gain
AGC_RSK_RSKp70_RPS6KB1_ST	P78371	CCT2	P23443	RPS6KB1	S115	A118S	118	Missense	distal	3	no	23.954	26.403	EPSD	ICGC	24.279	Gain
AGC_RSK_RSKp70_RPS6KB1_ST	P78371	CCT2	P23443	RPS6KB1	S143	A137V	137	Missense	distal	-6	no	31.119	31.158	EPSD	ICGC	24.279	Up-regulation
AGC_RSK_RSKp70_RPS6KB1_ST	P78371	CCT2	P23443	RPS6KB1	T166	G164D	164	Missense	proximal	-2	no	24.054	25.944	EPSD	ICGC	24.279	Gain
AGC_RSK_RSKp70_RPS6KB1_ST	P78371	CCT2	P23443	RPS6KB1	S212	F218L	218	Missense	distal	6	no	23.905	25.764	EPSD	ICGC;COSMIC	24.279	Gain
AGC_RSK_RSKp70_RPS6KB1_ST	P78371	CCT2	P23443	RPS6KB1	S212	E216A	216	Missense	distal	4	no	23.905	24.579	EPSD	ICGC	24.279	Gain
AGC_RSK_RSKp70_RPS6KB1_ST	P78371	CCT2	P23443	RPS6KB1	S260	E266A	266	Missense	distal	6	no	38.551	38.131	PhosphoSitePlus	ICGC;COSMIC	24.279	Down-regulation
AGC_RSK_RSKp70_RPS6KB1_ST	P78371	CCT2	P23443	RPS6KB1	S260	G253C	253	Missense	distal	-7	no	38.551	38.539	PhosphoSitePlus	ICGC	24.279	Down-regulation
AGC_RSK_RSKp70_RPS6KB1_ST	P78371	CCT2	P23443	RPS6KB1	S260	V264F	264	Missense	distal	4	no	38.551	37.603	PhosphoSitePlus	ICGC	24.279	Down-regulation
AGC_RSK_RSKp70_RPS6KB1_ST	P78371	CCT2	P23443	RPS6KB1	S260	E266G	266	Missense	distal	6	no	38.551	39.416	PhosphoSitePlus	ICGC	24.279	Up-regulation
AGC_RSK_RSKp70_RPS6KB1_ST	P78371	CCT2	P23443	RPS6KB1	S260	T261I	261	Missense	proximal	1	no	38.551	38.523	PhosphoSitePlus	ICGC	24.279	Down-regulation
AGC_RSK_RSKp70_RPS6KB1_ST	O60331	PIP5K1C	P23443	RPS6KB1	T69	A65E	65	Missense	distal	-4	no	26.322	25.941	EPSD	ICGC;COSMIC	24.279	Down-regulation
AGC_RSK_RSKp70_RPS6KB1_ST	O60331	PIP5K1C	P23443	RPS6KB1	S448	S449Y	449	Missense	proximal	1	no	33.501	34.864	EPSD	ICGC	24.279	Up-regulation
AGC_RSK_RSKp70_RPS6KB1_ST	O60331	PIP5K1C	P23443	RPS6KB1	S448	T442K	442	Missense	distal	-6	no	33.501	33.492	EPSD	ICGC;COSMIC	24.279	Down-regulation
AGC_RSK_RSKp70_RPS6KB1_ST	O60331	PIP5K1C	P23443	RPS6KB1	S448	S455P	455	Missense	distal	7	no	33.501	33.027	EPSD	ICGC;COSMIC	24.279	Down-regulation
AGC_RSK_RSKp70_RPS6KB1_ST	O60331	PIP5K1C	P23443	RPS6KB1	S449	S449Y	449	Missense	central	0	yes	25.884	0.000	EPSD	ICGC	24.279	Loss
AGC_RSK_RSKp70_RPS6KB1_ST	O60331	PIP5K1C	P23443	RPS6KB1	S449	T442K	442	Missense	distal	-7	no	25.884	25.883	EPSD	ICGC;COSMIC	24.279	Down-regulation
AGC_RSK_RSKp70_RPS6KB1_ST	O60331	PIP5K1C	P23443	RPS6KB1	S449	S455P	455	Missense	distal	6	no	25.884	24.909	EPSD	ICGC;COSMIC	24.279	Down-regulation
AGC_RSK_RSKp70_RPS6KB1_ST	O60331	PIP5K1C	P23443	RPS6KB1	S453	S449Y	449	Missense	distal	-4	no	36.855	35.831	EPSD	ICGC	24.279	Down-regulation
AGC_RSK_RSKp70_RPS6KB1_ST	O60331	PIP5K1C	P23443	RPS6KB1	S453	G458W	458	Missense	distal	5	no	36.855	34.228	EPSD	ICGC;COSMIC	24.279	Down-regulation
AGC_RSK_RSKp70_RPS6KB1_ST	O60331	PIP5K1C	P23443	RPS6KB1	S453	S455P	455	Missense	proximal	2	no	36.855	34.502	EPSD	ICGC;COSMIC	24.279	Down-regulation
AGC_RSK_RSKp70_RPS6KB1_ST	O60331	PIP5K1C	P23443	RPS6KB1	S496	D502E	502	Missense	distal	6	no	27.598	28.215	EPSD	ICGC	24.279	Up-regulation
AGC_RSK_RSKp70_RPS6KB1_ST	O60331	PIP5K1C	P23443	RPS6KB1	S496	L500M	500	Missense	distal	4	no	27.598	27.349	EPSD	ICGC	24.279	Down-regulation
AGC_RSK_RSKp70_RPS6KB1_ST	O60331	PIP5K1C	P23443	RPS6KB1	S496	R495S	495	Missense	proximal	-1	no	27.598	27.569	EPSD	ICGC;COSMIC	24.279	Down-regulation
AGC_RSK_RSKp70_RPS6KB1_ST	O60331	PIP5K1C	P23443	RPS6KB1	S523	T526A	526	Missense	distal	3	no	26.853	26.250	EPSD	ICGC;COSMIC	24.279	Down-regulation
AGC_RSK_RSKp70_RPS6KB1_ST	O60331	PIP5K1C	P23443	RPS6KB1	S539	P536H	536	Missense	distal	-3	no	22.478	31.611	EPSD	ICGC	24.279	Gain
AGC_RSK_RSKp70_RPS6KB1_ST	O60331	PIP5K1C	P23443	RPS6KB1	S541	P536H	536	Missense	distal	-5	no	24.868	30.492	EPSD	ICGC	24.279	Up-regulation
AGC_RSK_RSKp70_RPS6KB1_ST	O60331	PIP5K1C	P23443	RPS6KB1	S541	S544L	544	Missense	distal	3	no	24.868	23.168	EPSD	ICGC;COSMIC	24.279	Loss
AGC_RSK_RSKp70_RPS6KB1_ST	O60331	PIP5K1C	P23443	RPS6KB1	T553	T553A	553	Missense	central	0	yes	35.564	0.000	EPSD;PhosphoSitePlus	ICGC	24.279	Loss
AGC_RSK_RSKp70_RPS6KB1_ST	O60331	PIP5K1C	P23443	RPS6KB1	S555	P562L	562	Missense	distal	7	no	37.679	37.636	PhosphoSitePlus;EPSD	ICGC	24.279	Down-regulation
AGC_RSK_RSKp70_RPS6KB1_ST	O60331	PIP5K1C	P23443	RPS6KB1	S555	T553A	553	Missense	proximal	-2	no	37.679	37.704	PhosphoSitePlus;EPSD	ICGC	24.279	Up-regulation
AGC_RSK_RSKp70_RPS6KB1_ST	Q6R327	RICTOR	P23443	RPS6KB1	S21	N19S	19	Missense	proximal	-2	no	34.352	32.697	EPSD	ICGC;COSMIC	24.279	Down-regulation
AGC_RSK_RSKp70_RPS6KB1_ST	Q6R327	RICTOR	P23443	RPS6KB1	S35	N37K	37	Missense	proximal	2	no	31.100	33.450	EPSD	ICGC	24.279	Up-regulation
AGC_RSK_RSKp70_RPS6KB1_ST	Q6R327	RICTOR	P23443	RPS6KB1	S383	R380C	380	Missense	distal	-3	no	27.362	17.813	EPSD	ICGC;COSMIC	24.279	Loss
AGC_RSK_RSKp70_RPS6KB1_ST	Q6R327	RICTOR	P23443	RPS6KB1	S383	P385T	385	Missense	proximal	2	no	27.362	28.817	EPSD	ICGC	24.279	Up-regulation
AGC_RSK_RSKp70_RPS6KB1_ST	Q6R327	RICTOR	P23443	RPS6KB1	S383	L377F	377	Missense	distal	-6	no	27.362	27.417	EPSD	ICGC	24.279	Up-regulation
AGC_RSK_RSKp70_RPS6KB1_ST	Q6R327	RICTOR	P23443	RPS6KB1	S383	A381V	381	Missense	proximal	-2	no	27.362	27.939	EPSD	ICGC	24.279	Up-regulation
AGC_RSK_RSKp70_RPS6KB1_ST	Q6R327	RICTOR	P23443	RPS6KB1	T701	T701A	701	Missense	central	0	yes	27.589	0.000	EPSD	ICGC	24.279	Loss
AGC_RSK_RSKp70_RPS6KB1_ST	Q6R327	RICTOR	P23443	RPS6KB1	T701	L700R	700	Missense	proximal	-1	no	27.589	27.569	EPSD	ICGC;COSMIC	24.279	Down-regulation
AGC_RSK_RSKp70_RPS6KB1_ST	Q6R327	RICTOR	P23443	RPS6KB1	S703	L700R	700	Missense	distal	-3	no	17.040	26.707	EPSD	ICGC;COSMIC	24.279	Gain
AGC_RSK_RSKp70_RPS6KB1_ST	Q6R327	RICTOR	P23443	RPS6KB1	S704	T701A	701	Missense	distal	-3	no	30.862	30.893	EPSD	ICGC	24.279	Up-regulation
AGC_RSK_RSKp70_RPS6KB1_ST	Q6R327	RICTOR	P23443	RPS6KB1	S704	G711V	711	Missense	distal	7	no	30.862	30.323	EPSD	ICGC	24.279	Down-regulation
AGC_RSK_RSKp70_RPS6KB1_ST	Q6R327	RICTOR	P23443	RPS6KB1	S704	L700R	700	Missense	distal	-4	no	30.862	30.558	EPSD	ICGC;COSMIC	24.279	Down-regulation
AGC_RSK_RSKp70_RPS6KB1_ST	Q6R327	RICTOR	P23443	RPS6KB1	S704	R709G	709	Missense	distal	5	no	30.862	31.623	EPSD	ICGC;COSMIC	24.279	Up-regulation
AGC_RSK_RSKp70_RPS6KB1_ST	Q6R327	RICTOR	P23443	RPS6KB1	S810	L809F	809	Missense	proximal	-1	no	25.425	25.496	EPSD	ICGC;COSMIC	24.279	Up-regulation
AGC_RSK_RSKp70_RPS6KB1_ST	Q6R327	RICTOR	P23443	RPS6KB1	S837	S837F	837	Missense	central	0	yes	31.217	0.000	EPSD	ICGC;COSMIC	24.279	Loss
AGC_RSK_RSKp70_RPS6KB1_ST	Q6R327	RICTOR	P23443	RPS6KB1	S837	W831R	831	Missense	distal	-6	no	31.217	31.154	EPSD	ICGC;COSMIC	24.279	Down-regulation
AGC_RSK_RSKp70_RPS6KB1_ST	Q6R327	RICTOR	P23443	RPS6KB1	S1026	S1031C	1031	Missense	distal	5	no	29.112	25.715	EPSD	ICGC;COSMIC;GDSC;CCLE	24.279	Down-regulation
AGC_RSK_RSKp70_RPS6KB1_ST	Q6R327	RICTOR	P23443	RPS6KB1	S1028	S1031C	1031	Missense	distal	3	no	25.996	22.758	EPSD	ICGC;COSMIC;GDSC;CCLE	24.279	Loss
AGC_RSK_RSKp70_RPS6KB1_ST	Q6R327	RICTOR	P23443	RPS6KB1	S1035	S1031C	1031	Missense	distal	-4	no	29.070	26.620	EPSD	ICGC;COSMIC;GDSC;CCLE	24.279	Down-regulation
AGC_RSK_RSKp70_RPS6KB1_ST	Q6R327	RICTOR	P23443	RPS6KB1	S1037	S1031C	1031	Missense	distal	-6	no	31.384	31.431	EPSD	ICGC;COSMIC;GDSC;CCLE	24.279	Up-regulation
AGC_RSK_RSKp70_RPS6KB1_ST	Q6R327	RICTOR	P23443	RPS6KB1	S1122	P1115S	1115	Missense	distal	-7	no	26.492	26.281	EPSD	ICGC	24.279	Down-regulation
AGC_RSK_RSKp70_RPS6KB1_ST	Q6R327	RICTOR	P23443	RPS6KB1	S1211	V1204I	1204	Missense	distal	-7	no	30.296	30.139	EPSD	ICGC;COSMIC	24.279	Down-regulation
AGC_RSK_RSKp70_RPS6KB1_ST	Q6R327	RICTOR	P23443	RPS6KB1	S1211	R1216C	1216	Missense	distal	5	no	30.296	28.796	EPSD	ICGC;COSMIC	24.279	Down-regulation
AGC_RSK_RSKp70_RPS6KB1_ST	Q6R327	RICTOR	P23443	RPS6KB1	S1211	T1209M	1209	Missense	proximal	-2	no	30.296	29.927	EPSD	ICGC;COSMIC	24.279	Down-regulation
AGC_RSK_RSKp70_RPS6KB1_ST	Q6R327	RICTOR	P23443	RPS6KB1	S1219	R1216C	1216	Missense	distal	-3	no	36.673	27.124	EPSD	ICGC;COSMIC	24.279	Down-regulation
AGC_RSK_RSKp70_RPS6KB1_ST	Q6R327	RICTOR	P23443	RPS6KB1	S1227	M1232V	1232	Missense	distal	5	no	24.370	24.352	EPSD	ICGC;COSMIC	24.279	Down-regulation
AGC_RSK_RSKp70_RPS6KB1_ST	Q6R327	RICTOR	P23443	RPS6KB1	S1227	S1230T	1230	Missense	distal	3	no	24.370	22.524	EPSD	ICGC	24.279	Loss
AGC_RSK_RSKp70_RPS6KB1_ST	Q6R327	RICTOR	P23443	RPS6KB1	S1231	M1232V	1232	Missense	proximal	1	no	24.578	25.047	EPSD	ICGC;COSMIC	24.279	Up-regulation
AGC_RSK_RSKp70_RPS6KB1_ST	Q6R327	RICTOR	P23443	RPS6KB1	S1231	S1230T	1230	Missense	proximal	-1	no	24.578	24.606	EPSD	ICGC	24.279	Up-regulation
AGC_RSK_RSKp70_RPS6KB1_ST	Q6R327	RICTOR	P23443	RPS6KB1	S1235	M1232V	1232	Missense	distal	-3	no	29.045	19.791	EPSD	ICGC;COSMIC	24.279	Loss
AGC_RSK_RSKp70_RPS6KB1_ST	Q6R327	RICTOR	P23443	RPS6KB1	S1235	S1230T	1230	Missense	distal	-5	no	29.045	26.979	EPSD	ICGC	24.279	Down-regulation
AGC_RSK_RSKp70_RPS6KB1_ST	Q6R327	RICTOR	P23443	RPS6KB1	S1237	M1232V	1232	Missense	distal	-5	no	26.803	21.386	EPSD	ICGC;COSMIC	24.279	Loss
AGC_RSK_RSKp70_RPS6KB1_ST	Q6R327	RICTOR	P23443	RPS6KB1	S1237	S1230T	1230	Missense	distal	-7	no	26.803	26.857	EPSD	ICGC	24.279	Up-regulation
AGC_RSK_RSKp70_RPS6KB1_ST	Q6R327	RICTOR	P23443	RPS6KB1	S1274	H1276R	1276	Missense	proximal	2	no	24.836	24.315	EPSD	ICGC;COSMIC	24.279	Down-regulation
AGC_RSK_RSKp70_RPS6KB1_ST	Q6R327	RICTOR	P23443	RPS6KB1	S1274	Q1273K	1273	Missense	proximal	-1	no	24.836	24.848	EPSD	ICGC;COSMIC	24.279	Up-regulation
AGC_RSK_RSKp70_RPS6KB1_ST	Q6R327	RICTOR	P23443	RPS6KB1	S1278	Q1273K	1273	Missense	distal	-5	no	23.543	29.726	EPSD	ICGC;COSMIC	24.279	Gain
AGC_RSK_RSKp70_RPS6KB1_ST	Q6R327	RICTOR	P23443	RPS6KB1	S1302	L1296P	1296	Missense	distal	-6	no	29.044	29.051	EPSD	ICGC;COSMIC	24.279	Up-regulation
AGC_RSK_RSKp70_RPS6KB1_ST	Q6R327	RICTOR	P23443	RPS6KB1	S1344	S1348C	1348	Missense	distal	4	no	33.629	31.778	EPSD	ICGC;COSMIC	24.279	Down-regulation
AGC_RSK_RSKp70_RPS6KB1_ST	Q6R327	RICTOR	P23443	RPS6KB1	S1346	S1348C	1348	Missense	proximal	2	no	26.466	23.681	EPSD	ICGC;COSMIC	24.279	Loss
AGC_RSK_RSKp70_RPS6KB1_ST	Q6R327	RICTOR	P23443	RPS6KB1	S1346	S1353Y	1353	Missense	distal	7	no	26.466	25.768	EPSD	ICGC	24.279	Down-regulation
AGC_RSK_RSKp70_RPS6KB1_ST	Q6R327	RICTOR	P23443	RPS6KB1	S1348	S1348C	1348	Missense	central	0	yes	28.252	0.000	EPSD	ICGC;COSMIC	24.279	Loss
AGC_RSK_RSKp70_RPS6KB1_ST	Q6R327	RICTOR	P23443	RPS6KB1	S1348	S1353Y	1353	Missense	distal	5	no	28.252	24.288	EPSD	ICGC	24.279	Down-regulation
AGC_RSK_RSKp70_RPS6KB1_ST	Q6R327	RICTOR	P23443	RPS6KB1	S1588	S1588N	1588	Missense	central	0	yes	28.571	0.000	EPSD	ICGC	24.279	Loss
AGC_RSK_RSKp70_RPS6KB1_ST	Q6R327	RICTOR	P23443	RPS6KB1	S1588	S1581Y	1581	Missense	distal	-7	no	28.571	28.840	EPSD	ICGC;COSMIC	24.279	Up-regulation
AGC_RSK_RSKp70_RPS6KB1_ST	P78362	SRPK2	P23443	RPS6KB1	S5	E6D	6	Missense	proximal	1	no	25.045	24.400	EPSD	ICGC;COSMIC	24.279	Down-regulation
AGC_RSK_RSKp70_RPS6KB1_ST	P78362	SRPK2	P23443	RPS6KB1	S8	P14L	14	Missense	distal	6	no	23.500	24.319	EPSD	ICGC	24.279	Gain
AGC_RSK_RSKp70_RPS6KB1_ST	P78362	SRPK2	P23443	RPS6KB1	S9	P14L	14	Missense	distal	5	no	30.438	31.663	EPSD	ICGC	24.279	Up-regulation
AGC_RSK_RSKp70_RPS6KB1_ST	P78362	SRPK2	P23443	RPS6KB1	S9	E6D	6	Missense	distal	-3	no	30.438	29.333	EPSD	ICGC;COSMIC	24.279	Down-regulation
AGC_RSK_RSKp70_RPS6KB1_ST	P78362	SRPK2	P23443	RPS6KB1	S11	P14L	14	Missense	distal	3	no	28.531	29.371	EPSD	ICGC	24.279	Up-regulation
AGC_RSK_RSKp70_RPS6KB1_ST	P78362	SRPK2	P23443	RPS6KB1	S11	Q18K	18	Missense	distal	7	no	28.531	28.264	EPSD	ICGC	24.279	Down-regulation
AGC_RSK_RSKp70_RPS6KB1_ST	P78362	SRPK2	P23443	RPS6KB1	S11	E6D	6	Missense	distal	-5	no	28.531	24.641	EPSD	ICGC;COSMIC	24.279	Down-regulation
AGC_RSK_RSKp70_RPS6KB1_ST	P78362	SRPK2	P23443	RPS6KB1	S248	P245H	245	Missense	distal	-3	no	20.766	29.899	EPSD	ICGC;COSMIC	24.279	Gain
AGC_RSK_RSKp70_RPS6KB1_ST	P78362	SRPK2	P23443	RPS6KB1	S393	Q396L	396	Missense	distal	3	no	23.166	24.360	EPSD	ICGC;COSMIC	24.279	Gain
AGC_RSK_RSKp70_RPS6KB1_ST	P78362	SRPK2	P23443	RPS6KB1	S475	Q480K	480	Missense	distal	5	no	28.695	28.765	EPSD	ICGC	24.279	Up-regulation
AGC_RSK_RSKp70_RPS6KB1_ST	P78362	SRPK2	P23443	RPS6KB1	S475	E482D	482	Missense	distal	7	no	28.695	27.841	EPSD	ICGC;COSMIC	24.279	Down-regulation
AGC_RSK_RSKp70_RPS6KB1_ST	P78362	SRPK2	P23443	RPS6KB1	S483	Q480K	480	Missense	distal	-3	no	17.620	29.056	EPSD	ICGC	24.279	Gain
AGC_RSK_RSKp70_RPS6KB1_ST	P78362	SRPK2	P23443	RPS6KB1	S490	D488Y	488	Missense	proximal	-2	no	30.252	29.525	EPSD	ICGC;COSMIC	24.279	Down-regulation
AGC_RSK_RSKp70_RPS6KB1_ST	P78362	SRPK2	P23443	RPS6KB1	S490	V493L	493	Missense	distal	3	no	30.252	30.619	EPSD	ICGC;COSMIC	24.279	Up-regulation
AGC_RSK_RSKp70_RPS6KB1_ST	P78362	SRPK2	P23443	RPS6KB1	T492	D488Y	488	Missense	distal	-4	no	25.320	25.461	EPSD	ICGC;COSMIC	24.279	Up-regulation
AGC_RSK_RSKp70_RPS6KB1_ST	P78362	SRPK2	P23443	RPS6KB1	T492	V493L	493	Missense	proximal	1	no	25.320	25.751	EPSD	ICGC;COSMIC	24.279	Up-regulation
AGC_RSK_RSKp70_RPS6KB1_ST	P78362	SRPK2	P23443	RPS6KB1	S494	D500N	500	Missense	distal	6	no	31.477	31.337	PhosphoSitePlus	ICGC;COSMIC	24.279	Down-regulation
AGC_RSK_RSKp70_RPS6KB1_ST	P78362	SRPK2	P23443	RPS6KB1	S494	D488Y	488	Missense	distal	-6	no	31.477	31.495	PhosphoSitePlus	ICGC;COSMIC	24.279	Up-regulation
AGC_RSK_RSKp70_RPS6KB1_ST	P78362	SRPK2	P23443	RPS6KB1	S494	V493L	493	Missense	proximal	-1	no	31.477	31.461	PhosphoSitePlus	ICGC;COSMIC	24.279	Down-regulation
AGC_RSK_RSKp70_RPS6KB1_ST	P78362	SRPK2	P23443	RPS6KB1	S494	D500Y	500	Missense	distal	6	no	31.477	31.315	PhosphoSitePlus	ICGC;COSMIC	24.279	Down-regulation
AGC_RSK_RSKp70_RPS6KB1_ST	P78362	SRPK2	P23443	RPS6KB1	S496	P502T	502	Missense	distal	6	no	29.049	30.092	EPSD	ICGC	24.279	Up-regulation
AGC_RSK_RSKp70_RPS6KB1_ST	P78362	SRPK2	P23443	RPS6KB1	S496	D500N	500	Missense	distal	4	no	29.049	29.063	EPSD	ICGC;COSMIC	24.279	Up-regulation
AGC_RSK_RSKp70_RPS6KB1_ST	P78362	SRPK2	P23443	RPS6KB1	S496	V493L	493	Missense	distal	-3	no	29.049	34.135	EPSD	ICGC;COSMIC	24.279	Up-regulation
AGC_RSK_RSKp70_RPS6KB1_ST	P78362	SRPK2	P23443	RPS6KB1	S496	D500Y	500	Missense	distal	4	no	29.049	28.743	EPSD	ICGC;COSMIC	24.279	Down-regulation
AGC_RSK_RSKp70_RPS6KB1_ST	P23588	EIF4B	P23443	RPS6KB1	S93	A98S	98	Missense	distal	5	no	28.236	29.964	EPSD	ICGC	24.279	Up-regulation
AGC_RSK_RSKp70_RPS6KB1_ST	P23588	EIF4B	P23443	RPS6KB1	S93	R89L	89	Missense	distal	-4	no	28.236	28.540	EPSD	ICGC	24.279	Up-regulation
AGC_RSK_RSKp70_RPS6KB1_ST	P23588	EIF4B	P23443	RPS6KB1	S131	E134Q	134	Missense	distal	3	no	27.474	24.346	EPSD	ICGC;COSMIC	24.279	Down-regulation
AGC_RSK_RSKp70_RPS6KB1_ST	P23588	EIF4B	P23443	RPS6KB1	S131	R135K	135	Missense	distal	4	no	27.474	28.391	EPSD	ICGC;COSMIC	24.279	Up-regulation
AGC_RSK_RSKp70_RPS6KB1_ST	P23588	EIF4B	P23443	RPS6KB1	S131	R128L	128	Missense	distal	-3	no	27.474	17.807	EPSD	ICGC;COSMIC	24.279	Loss
AGC_RSK_RSKp70_RPS6KB1_ST	P23588	EIF4B	P23443	RPS6KB1	S230	R234W	234	Missense	distal	4	no	30.025	29.229	EPSD	ICGC;COSMIC	24.279	Down-regulation
AGC_RSK_RSKp70_RPS6KB1_ST	P23588	EIF4B	P23443	RPS6KB1	S230	G236C	236	Missense	distal	6	no	30.025	28.856	EPSD	ICGC	24.279	Down-regulation
AGC_RSK_RSKp70_RPS6KB1_ST	P23588	EIF4B	P23443	RPS6KB1	S276	R279Q	279	Missense	distal	3	no	26.212	24.886	EPSD	ICGC;COSMIC	24.279	Down-regulation
AGC_RSK_RSKp70_RPS6KB1_ST	P23588	EIF4B	P23443	RPS6KB1	S309	D307N	307	Missense	proximal	-2	no	24.979	24.964	EPSD	ICGC;COSMIC	24.279	Down-regulation
AGC_RSK_RSKp70_RPS6KB1_ST	P23588	EIF4B	P23443	RPS6KB1	S311	D307N	307	Missense	distal	-4	no	28.465	28.190	EPSD	ICGC;COSMIC	24.279	Down-regulation
AGC_RSK_RSKp70_RPS6KB1_ST	P23588	EIF4B	P23443	RPS6KB1	S406	R399Q	399	Missense	distal	-7	no	26.685	26.755	EPSD	ICGC;COSMIC	24.279	Up-regulation
AGC_RSK_RSKp70_RPS6KB1_ST	P23588	EIF4B	P23443	RPS6KB1	S406	S406Y	406	Missense	central	0	yes	26.685	0.000	EPSD	ICGC	24.279	Loss
AGC_RSK_RSKp70_RPS6KB1_ST	Q9BY77	POLDIP3	P23443	RPS6KB1	S254	T256K	256	Missense	proximal	2	no	29.605	29.349	EPSD	ICGC;COSMIC	24.279	Down-regulation
AGC_RSK_RSKp70_RPS6KB1_ST	Q9BY77	POLDIP3	P23443	RPS6KB1	S383	P390S	390	Missense	distal	7	no	35.954	36.427	PhosphoSitePlus;EPSD	ICGC	24.279	Up-regulation
AGC_RSK_RSKp70_RPS6KB1_ST	Q9BY77	POLDIP3	P23443	RPS6KB1	S385	P390S	390	Missense	distal	5	no	35.699	37.634	EPSD;PhosphoSitePlus	ICGC	24.279	Up-regulation
Atypical_Alpha_ChaK_TRPM7_ST	Q96QT4	TRPM7	Q96QT4	TRPM7	T89	P88Q	88	Missense	proximal	-1	no	3.909	3.396	EPSD	ICGC	3.661	Loss
Atypical_Alpha_ChaK_TRPM7_ST	Q96QT4	TRPM7	Q96QT4	TRPM7	S1191	K1188R	1188	Missense	distal	-3	no	4.075	4.074	EPSD;PhosphoSitePlus	ICGC;COSMIC	3.661	Down-regulation
Atypical_Alpha_ChaK_TRPM7_ST	Q96QT4	TRPM7	Q96QT4	TRPM7	S1191	E1195K	1195	Missense	distal	4	no	4.075	4.024	EPSD;PhosphoSitePlus	ICGC;COSMIC	3.661	Down-regulation
Atypical_Alpha_ChaK_TRPM7_ST	Q96QT4	TRPM7	Q96QT4	TRPM7	S1193	V1199I	1199	Missense	distal	6	no	3.735	3.674	PhosphoSitePlus;EPSD	ICGC;COSMIC	3.661	Down-regulation
Atypical_Alpha_ChaK_TRPM7_ST	Q96QT4	TRPM7	Q96QT4	TRPM7	S1193	K1188R	1188	Missense	distal	-5	no	3.735	3.780	PhosphoSitePlus;EPSD	ICGC;COSMIC	3.661	Up-regulation
Atypical_Alpha_ChaK_TRPM7_ST	Q96QT4	TRPM7	Q96QT4	TRPM7	S1193	E1195K	1195	Missense	proximal	2	no	3.735	3.801	PhosphoSitePlus;EPSD	ICGC;COSMIC	3.661	Up-regulation
Atypical_Alpha_ChaK_TRPM7_ST	Q96QT4	TRPM7	Q96QT4	TRPM7	S1387	L1384S	1384	Missense	distal	-3	no	4.463	4.360	EPSD;PhosphoSitePlus	ICGC	3.661	Down-regulation
Atypical_Alpha_ChaK_TRPM7_ST	Q96QT4	TRPM7	Q96QT4	TRPM7	S1390	L1384S	1384	Missense	distal	-6	no	4.119	3.967	EPSD;PhosphoSitePlus	ICGC	3.661	Down-regulation
Atypical_Alpha_ChaK_TRPM7_ST	Q96QT4	TRPM7	Q96QT4	TRPM7	T1435	A1439V	1439	Missense	distal	4	no	4.560	4.532	EPSD;PhosphoSitePlus	ICGC	3.661	Down-regulation
Atypical_Alpha_ChaK_TRPM7_ST	Q96QT4	TRPM7	Q96QT4	TRPM7	S1446	A1439V	1439	Missense	distal	-7	no	4.149	4.094	EPSD;PhosphoSitePlus	ICGC	3.661	Down-regulation
Atypical_Alpha_ChaK_TRPM7_ST	Q96QT4	TRPM7	Q96QT4	TRPM7	S1456	K1460Q	1460	Missense	distal	4	no	3.648	3.707	EPSD;PhosphoSitePlus	ICGC;COSMIC	3.661	Gain
Atypical_Alpha_ChaK_TRPM7_ST	Q96QT4	TRPM7	Q96QT4	TRPM7	S1468	S1468P	1468	Missense	central	0	yes	3.848	0.000	EPSD;PhosphoSitePlus	ICGC;COSMIC	3.661	Loss
Atypical_Alpha_ChaK_TRPM7_ST	Q96QT4	TRPM7	Q96QT4	TRPM7	T1471	S1468P	1468	Missense	distal	-3	no	4.008	4.137	EPSD;PhosphoSitePlus	ICGC;COSMIC	3.661	Up-regulation
Atypical_Alpha_ChaK_TRPM7_ST	Q96QT4	TRPM7	Q96QT4	TRPM7	S1476	T1482I	1482	Missense	distal	6	no	3.667	3.499	EPSD;PhosphoSitePlus	ICGC;COSMIC	3.661	Loss
Atypical_Alpha_ChaK_TRPM7_ST	Q96QT4	TRPM7	Q96QT4	TRPM7	S1493	P1490H	1490	Missense	distal	-3	no	4.135	4.089	EPSD;PhosphoSitePlus	ICGC;COSMIC	3.661	Down-regulation
Atypical_Alpha_ChaK_TRPM7_ST	Q96QT4	TRPM7	Q96QT4	TRPM7	S1493	K1494R	1494	Missense	proximal	1	no	4.135	4.092	EPSD;PhosphoSitePlus	ICGC;COSMIC	3.661	Down-regulation
Atypical_Alpha_ChaK_TRPM7_ST	Q96QT4	TRPM7	Q96QT4	TRPM7	T1551	Y1554C	1554	Missense	distal	3	no	4.951	4.772	EPSD;PhosphoSitePlus	ICGC;COSMIC	3.661	Down-regulation
Atypical_Alpha_ChaK_TRPM7_ST	P35579	MYH9	Q96QT4	TRPM7	S1803	A1807S	1807	Missense	distal	4	no	4.692	4.749	EPSD;PhosphoSitePlus	ICGC;COSMIC	3.661	Up-regulation
Atypical_Alpha_ChaK_TRPM7_ST	P35579	MYH9	Q96QT4	TRPM7	S1808	A1811T	1811	Missense	distal	3	no	3.994	3.948	PhosphoSitePlus;EPSD	ICGC;COSMIC	3.661	Down-regulation
Atypical_Alpha_ChaK_TRPM7_ST	P35579	MYH9	Q96QT4	TRPM7	S1808	A1807S	1807	Missense	proximal	-1	no	3.994	3.618	PhosphoSitePlus;EPSD	ICGC;COSMIC	3.661	Loss
Atypical_Alpha_ChaK_TRPM7_ST	P04083	ANXA1	Q96QT4	TRPM7	S5	V4L	4	Missense	proximal	-1	no	5.136	5.176	PhosphoSitePlus	ICGC	3.661	Up-regulation
Atypical_Alpha_ChaK_TRPM7_ST	O00418	EEF2K	Q96QT4	TRPM7	T43	T43M	43	Missense	central	0	yes	3.765	0.000	EPSD	ICGC;COSMIC	3.661	Loss
Atypical_Alpha_ChaK_TRPM7_ST	O00418	EEF2K	Q96QT4	TRPM7	T43	P41T	41	Missense	proximal	-2	no	3.765	3.579	EPSD	ICGC;COSMIC	3.661	Loss
Atypical_Alpha_ChaK_TRPM7_ST	O00418	EEF2K	Q96QT4	TRPM7	T43	P41H	41	Missense	proximal	-2	no	3.765	3.481	EPSD	ICGC;COSMIC	3.661	Loss
Atypical_Alpha_ChaK_TRPM7_ST	O00418	EEF2K	Q96QT4	TRPM7	S47	T43M	43	Missense	distal	-4	no	4.086	4.251	EPSD	ICGC;COSMIC	3.661	Up-regulation
Atypical_Alpha_ChaK_TRPM7_ST	O00418	EEF2K	Q96QT4	TRPM7	S47	N53S	53	Missense	distal	6	no	4.086	4.240	EPSD	ICGC;COSMIC	3.661	Up-regulation
Atypical_Alpha_ChaK_TRPM7_ST	O00418	EEF2K	Q96QT4	TRPM7	S47	P41T	41	Missense	distal	-6	no	4.086	4.041	EPSD	ICGC;COSMIC	3.661	Down-regulation
Atypical_Alpha_ChaK_TRPM7_ST	O00418	EEF2K	Q96QT4	TRPM7	S47	P41H	41	Missense	distal	-6	no	4.086	3.985	EPSD	ICGC;COSMIC	3.661	Down-regulation
Atypical_Alpha_ChaK_TRPM7_ST	O00418	EEF2K	Q96QT4	TRPM7	S72	S71F	71	Missense	proximal	-1	no	2.954	3.670	EPSD	ICGC;COSMIC	3.661	Gain
Atypical_Alpha_ChaK_TRPM7_ST	O00418	EEF2K	Q96QT4	TRPM7	S74	P75A	75	Missense	proximal	1	no	3.677	3.751	EPSD	ICGC;COSMIC	3.661	Up-regulation
Atypical_Alpha_ChaK_TRPM7_ST	O00418	EEF2K	Q96QT4	TRPM7	S74	P75L	75	Missense	proximal	1	no	3.677	3.711	EPSD	ICGC;COSMIC	3.661	Up-regulation
Atypical_Alpha_ChaK_TRPM7_ST	O00418	EEF2K	Q96QT4	TRPM7	S74	S71F	71	Missense	distal	-3	no	3.677	3.846	EPSD	ICGC;COSMIC	3.661	Up-regulation
Atypical_Alpha_ChaK_TRPM7_ST	O00418	EEF2K	Q96QT4	TRPM7	S74	F79L	79	Missense	distal	5	no	3.677	3.922	EPSD	ICGC	3.661	Up-regulation
Atypical_Alpha_ChaK_TRPM7_ST	O00418	EEF2K	Q96QT4	TRPM7	S78	P75A	75	Missense	distal	-3	no	4.007	3.942	PhosphoSitePlus	ICGC;COSMIC	3.661	Down-regulation
Atypical_Alpha_ChaK_TRPM7_ST	O00418	EEF2K	Q96QT4	TRPM7	S78	P75L	75	Missense	distal	-3	no	4.007	3.982	PhosphoSitePlus	ICGC;COSMIC	3.661	Down-regulation
Atypical_Alpha_ChaK_TRPM7_ST	O00418	EEF2K	Q96QT4	TRPM7	S78	S71F	71	Missense	distal	-7	no	4.007	3.793	PhosphoSitePlus	ICGC;COSMIC	3.661	Down-regulation
Atypical_Alpha_ChaK_TRPM7_ST	O00418	EEF2K	Q96QT4	TRPM7	S78	F79L	79	Missense	proximal	1	no	4.007	4.183	PhosphoSitePlus	ICGC	3.661	Up-regulation
Atypical_Alpha_ChaK_TRPM7_ST	O00418	EEF2K	Q96QT4	TRPM7	S345	K347N	347	Missense	proximal	2	no	3.923	3.939	EPSD	ICGC;COSMIC	3.661	Up-regulation
Atypical_Alpha_ChaK_TRPM7_ST	O00418	EEF2K	Q96QT4	TRPM7	S366	R369W	369	Missense	distal	3	no	4.399	4.207	EPSD	ICGC	3.661	Down-regulation
Atypical_Alpha_ChaK_TRPM7_ST	O00418	EEF2K	Q96QT4	TRPM7	S366	Q361R	361	Missense	distal	-5	no	4.399	4.366	EPSD	ICGC	3.661	Down-regulation
Atypical_Alpha_ChaK_TRPM7_ST	O00418	EEF2K	Q96QT4	TRPM7	S366	P360L	360	Missense	distal	-6	no	4.399	4.309	EPSD	ICGC	3.661	Down-regulation
Atypical_Alpha_ChaK_TRPM7_ST	O00418	EEF2K	Q96QT4	TRPM7	S622	D629Y	629	Missense	distal	7	no	3.713	3.041	EPSD	ICGC;COSMIC	3.661	Loss
Atypical_Alpha_ChaK_TRPM7_ST	P28289	TMOD1	Q96QT4	TRPM7	T54	T59M	59	Missense	distal	5	no	3.731	2.999	EPSD;PhosphoSitePlus	ICGC;COSMIC	3.661	Loss
Atypical_Alpha_ChaK_TRPM7_ST	P28289	TMOD1	Q96QT4	TRPM7	T54	G47V	47	Missense	distal	-7	no	3.731	3.755	EPSD;PhosphoSitePlus	ICGC;COSMIC	3.661	Up-regulation
TK_Axl_MERTK_Y	Q12866	MERTK	Q12866	MERTK	Y749	G751R	751	Missense	proximal	2	no	5.292	5.345	PhosphoSitePlus;EPSD	ICGC;COSMIC	1.889	Up-regulation
TK_Axl_MERTK_Y	Q12866	MERTK	Q12866	MERTK	Y753	G757A	757	Missense	distal	4	no	6.115	6.090	EPSD;PhosphoSitePlus	ICGC;COSMIC	1.889	Down-regulation
TK_Axl_MERTK_Y	Q12866	MERTK	Q12866	MERTK	Y753	G751R	751	Missense	proximal	-2	no	6.115	6.023	EPSD;PhosphoSitePlus	ICGC;COSMIC	1.889	Down-regulation
TK_Axl_MERTK_Y	Q12866	MERTK	Q12866	MERTK	Y754	G757A	757	Missense	distal	3	no	5.341	5.418	EPSD;PhosphoSitePlus	ICGC;COSMIC	1.889	Up-regulation
TK_Axl_MERTK_Y	Q12866	MERTK	Q12866	MERTK	Y754	G751R	751	Missense	distal	-3	no	5.341	5.283	EPSD;PhosphoSitePlus	ICGC;COSMIC	1.889	Down-regulation
TK_Axl_MERTK_Y	P42229	STAT5A	Q12866	MERTK	Y171	Q175H	175	Missense	distal	4	no	1.910	1.816	EPSD	ICGC;COSMIC	1.889	Loss
TK_Axl_MERTK_Y	P51692	STAT5B	Q12866	MERTK	Y171	F172I	172	Missense	proximal	1	no	2.073	1.986	EPSD	ICGC;COSMIC	1.889	Down-regulation
TK_Axl_MERTK_Y	P51692	STAT5B	Q12866	MERTK	Y699	A695S	695	Missense	distal	-4	no	5.619	5.594	PhosphoSitePlus	ICGC;COSMIC	1.889	Down-regulation
TK_Axl_MERTK_Y	P40763	STAT3	Q12866	MERTK	Y686	P689T	689	Missense	distal	3	no	2.832	2.866	EPSD	ICGC	1.889	Up-regulation
TK_Axl_MERTK_Y	P40763	STAT3	Q12866	MERTK	Y686	S691C	691	Missense	distal	5	no	2.832	3.004	EPSD	ICGC;COSMIC	1.889	Up-regulation
TK_Axl_MERTK_Y	P40763	STAT3	Q12866	MERTK	Y686	R688W	688	Missense	proximal	2	no	2.832	2.666	EPSD	ICGC;COSMIC;GDSC;CCLE	1.889	Down-regulation
TK_Axl_MERTK_Y	P40763	STAT3	Q12866	MERTK	Y705	A702T	702	Missense	distal	-3	no	5.687	5.481	PhosphoSitePlus	ICGC;COSMIC	1.889	Down-regulation
STE_STE20_PAKB_PAK6_ST	Q00987	MDM2	Q9NQU5	PAK6	S186	S190C	190	Missense	distal	4	no	4.446	4.457	EPSD;PhosphoSitePlus	ICGC;COSMIC	1.514	Up-regulation
STE_STE20_PAKB_PAK6_ST	Q00987	MDM2	Q9NQU5	PAK6	S220	S215L	215	Missense	distal	-5	no	2.175	2.207	EPSD	ICGC;COSMIC	1.514	Up-regulation
STE_STE20_PAKB_PAK6_ST	Q00987	MDM2	Q9NQU5	PAK6	T288	E285D	285	Missense	distal	-3	no	1.665	1.556	EPSD	ICGC;COSMIC	1.514	Down-regulation
STE_STE20_PAKB_PAK6_ST	Q00987	MDM2	Q9NQU5	PAK6	S395	S400C	400	Missense	distal	5	no	1.569	1.952	EPSD	ICGC;COSMIC	1.514	Up-regulation
STE_STE20_PAKB_PAK6_ST	Q00987	MDM2	Q9NQU5	PAK6	S395	E390Q	390	Missense	distal	-5	no	1.569	1.462	EPSD	ICGC;COSMIC	1.514	Loss
STE_STE20_PAKB_PAK6_ST	Q00987	MDM2	Q9NQU5	PAK6	S425	V426F	426	Missense	proximal	1	no	1.528	1.520	EPSD	ICGC	1.514	Down-regulation
STE_STE20_PAKB_PAK6_ST	Q9BY11	PACSIN1	Q9NQU5	PAK6	T28	V29L	29	Missense	proximal	1	no	2.423	2.444	EPSD	ICGC	1.514	Up-regulation
STE_STE20_PAKB_PAK6_ST	Q9BY11	PACSIN1	Q9NQU5	PAK6	S339	A334V	334	Missense	distal	-5	no	1.782	1.625	EPSD	ICGC;COSMIC	1.514	Down-regulation
STE_STE20_PAKB_PAK6_ST	Q9BY11	PACSIN1	Q9NQU5	PAK6	S339	A334E	334	Missense	distal	-5	no	1.782	1.756	EPSD	ICGC;COSMIC	1.514	Down-regulation
STE_STE20_PAKB_PAK6_ST	Q9BY11	PACSIN1	Q9NQU5	PAK6	S339	T338A	338	Missense	proximal	-1	no	1.782	1.759	EPSD	ICGC;COSMIC	1.514	Down-regulation
STE_STE20_PAKB_PAK6_ST	P56545	CTBP2	Q9NQU5	PAK6	T84	T86S	86	Missense	proximal	2	no	1.068	1.616	EPSD	ICGC;COSMIC	1.514	Gain
STE_STE20_PAKB_PAK6_ST	P56545	CTBP2	Q9NQU5	PAK6	T88	T86S	86	Missense	proximal	-2	no	1.747	1.795	EPSD	ICGC;COSMIC	1.514	Up-regulation
STE_STE20_PAKB_PAK6_ST	P56545	CTBP2	Q9NQU5	PAK6	T88	L87I	87	Missense	proximal	-1	no	1.747	1.757	EPSD	ICGC;COSMIC	1.514	Up-regulation
STE_STE20_PAKB_PAK6_ST	P56545	CTBP2	Q9NQU5	PAK6	T433	A426G	426	Missense	distal	-7	no	1.605	1.708	EPSD	ICGC;COSMIC	1.514	Up-regulation
STE_STE20_PAKB_PAK6_ST	P56545	CTBP2	Q9NQU5	PAK6	T433	K434I	434	Missense	proximal	1	no	1.605	1.639	EPSD	ICGC;COSMIC	1.514	Up-regulation
STE_STE20_PAKB_PAK6_ST	P56545	CTBP2	Q9NQU5	PAK6	T433	N438S	438	Missense	distal	5	no	1.605	1.566	EPSD	ICGC;COSMIC	1.514	Down-regulation
STE_STE20_PAKB_PAK6_ST	P10275	AR	Q9NQU5	PAK6	S310	T317A	317	Missense	distal	7	no	1.567	1.525	EPSD	ICGC;COSMIC	1.514	Down-regulation
STE_STE20_PAKB_PAK6_ST	P10275	AR	Q9NQU5	PAK6	S310	T303S	303	Missense	distal	-7	no	1.567	1.505	EPSD	ICGC;COSMIC	1.514	Loss
STE_STE20_PAKB_PAK6_ST	P10275	AR	Q9NQU5	PAK6	S310	G314R	314	Missense	distal	4	no	1.567	1.554	EPSD	ICGC	1.514	Down-regulation
STE_STE20_PAKB_PAK6_ST	P10275	AR	Q9NQU5	PAK6	S579	K581N	581	Missense	proximal	2	no	4.575	4.428	PhosphoSitePlus	ICGC;COSMIC	1.514	Down-regulation
STE_STE20_PAKB_PAK6_ST	P10275	AR	Q9NQU5	PAK6	S579	L575P	575	Missense	distal	-4	no	4.575	4.574	PhosphoSitePlus	ICGC;COSMIC	1.514	Down-regulation
STE_STE20_PAKB_PAK6_ST	P53667	LIMK1	Q9NQU5	PAK6	T261	L266M	266	Missense	distal	5	no	1.574	1.185	EPSD	ICGC;COSMIC	1.514	Loss
STE_STE20_PAKB_PAK6_ST	P53667	LIMK1	Q9NQU5	PAK6	T270	L266M	266	Missense	distal	-4	no	2.045	2.044	EPSD	ICGC;COSMIC	1.514	Down-regulation
STE_STE20_PAKB_PAK6_ST	P53667	LIMK1	Q9NQU5	PAK6	S296	R295Q	295	Missense	proximal	-1	no	1.769	1.782	EPSD	ICGC;COSMIC	1.514	Up-regulation
STE_STE20_PAKA_PAK1_ST	P36871	PGM1	Q13153	PAK1	S134	P140L	140	Missense	distal	6	no	20.564	20.588	EPSD	ICGC	19.028	Up-regulation
STE_STE20_PAKA_PAK1_ST	P36871	PGM1	Q13153	PAK1	S134	P140S	140	Missense	distal	6	no	20.564	20.317	EPSD	ICGC	19.028	Down-regulation
STE_STE20_PAKA_PAK1_ST	P36871	PGM1	Q13153	PAK1	T185	I188S	188	Missense	distal	3	no	23.672	22.134	EPSD	ICGC	19.028	Down-regulation
STE_STE20_PAKA_PAK1_ST	P51114	FXR1	Q13153	PAK1	S60	P53H	53	Missense	distal	-7	no	22.108	21.584	EPSD	ICGC;COSMIC	19.028	Down-regulation
STE_STE20_PAKA_PAK1_ST	P51114	FXR1	Q13153	PAK1	T396	G389V	389	Missense	distal	-7	no	21.243	20.575	EPSD	ICGC	19.028	Down-regulation
STE_STE20_PAKA_PAK1_ST	P51114	FXR1	Q13153	PAK1	T396	R390L	390	Missense	distal	-6	no	21.243	19.022	EPSD	ICGC	19.028	Loss
STE_STE20_PAKA_PAK1_ST	P51114	FXR1	Q13153	PAK1	S420	R415C	415	Missense	distal	-5	no	21.034	21.789	PhosphoSitePlus	ICGC;COSMIC	19.028	Up-regulation
STE_STE20_PAKA_PAK1_ST	P51114	FXR1	Q13153	PAK1	S420	D417N	417	Missense	distal	-3	no	21.034	18.959	PhosphoSitePlus	ICGC;COSMIC	19.028	Loss
STE_STE20_PAKA_PAK1_ST	P51114	FXR1	Q13153	PAK1	S420	A425T	425	Missense	distal	5	no	21.034	21.021	PhosphoSitePlus	ICGC;COSMIC	19.028	Down-regulation
STE_STE20_PAKA_PAK1_ST	P51114	FXR1	Q13153	PAK1	S420	E418K	418	Missense	proximal	-2	no	21.034	23.516	PhosphoSitePlus	ICGC	19.028	Up-regulation
STE_STE20_PAKA_PAK1_ST	P51114	FXR1	Q13153	PAK1	S432	R436C	436	Missense	distal	4	no	17.936	19.929	EPSD	ICGC;COSMIC	19.028	Gain
STE_STE20_PAKA_PAK1_ST	P51114	FXR1	Q13153	PAK1	S438	R441H	441	Missense	distal	3	no	20.036	20.290	EPSD	ICGC;COSMIC	19.028	Up-regulation
STE_STE20_PAKA_PAK1_ST	P51114	FXR1	Q13153	PAK1	S438	D431N	431	Missense	distal	-7	no	20.036	19.631	EPSD	ICGC	19.028	Down-regulation
STE_STE20_PAKA_PAK1_ST	P51114	FXR1	Q13153	PAK1	S438	R436C	436	Missense	proximal	-2	no	20.036	7.315	EPSD	ICGC;COSMIC	19.028	Loss
STE_STE20_PAKA_PAK1_ST	P51114	FXR1	Q13153	PAK1	S438	D431Y	431	Missense	distal	-7	no	20.036	18.787	EPSD	ICGC;COSMIC	19.028	Loss
STE_STE20_PAKA_PAK1_ST	P51114	FXR1	Q13153	PAK1	S438	G443E	443	Missense	distal	5	no	20.036	20.006	EPSD	ICGC	19.028	Down-regulation
STE_STE20_PAKA_PAK1_ST	P51114	FXR1	Q13153	PAK1	S448	R441H	441	Missense	distal	-7	no	23.559	22.209	EPSD	ICGC;COSMIC	19.028	Down-regulation
STE_STE20_PAKA_PAK1_ST	P51114	FXR1	Q13153	PAK1	S448	R453Q	453	Missense	distal	5	no	23.559	23.557	EPSD	ICGC;COSMIC	19.028	Down-regulation
STE_STE20_PAKA_PAK1_ST	P51114	FXR1	Q13153	PAK1	S448	G443E	443	Missense	distal	-5	no	23.559	22.701	EPSD	ICGC	19.028	Down-regulation
STE_STE20_PAKA_PAK1_ST	P51114	FXR1	Q13153	PAK1	S448	R455C	455	Missense	distal	7	no	23.559	23.797	EPSD	ICGC;COSMIC	19.028	Up-regulation
STE_STE20_PAKA_PAK1_ST	P51114	FXR1	Q13153	PAK1	S450	R453Q	453	Missense	distal	3	no	20.541	21.040	EPSD	ICGC;COSMIC	19.028	Up-regulation
STE_STE20_PAKA_PAK1_ST	P51114	FXR1	Q13153	PAK1	S450	G443E	443	Missense	distal	-7	no	20.541	22.157	EPSD	ICGC	19.028	Up-regulation
STE_STE20_PAKA_PAK1_ST	P51114	FXR1	Q13153	PAK1	S450	R455C	455	Missense	distal	5	no	20.541	20.564	EPSD	ICGC;COSMIC	19.028	Up-regulation
STE_STE20_PAKA_PAK1_ST	P51114	FXR1	Q13153	PAK1	T511	M518I	518	Missense	distal	7	no	30.028	29.899	EPSD	ICGC;COSMIC	19.028	Down-regulation
STE_STE20_PAKA_PAK1_ST	P51114	FXR1	Q13153	PAK1	T511	D514N	514	Missense	distal	3	no	30.028	30.305	EPSD	ICGC;COSMIC	19.028	Up-regulation
STE_STE20_PAKA_PAK1_ST	P51114	FXR1	Q13153	PAK1	T522	G520R	520	Missense	proximal	-2	no	10.106	19.669	EPSD	ICGC;COSMIC	19.028	Gain
STE_STE20_PAKA_PAK1_ST	Q13153	PAK1	Q13153	PAK1	S21	G27S	27	Missense	distal	6	no	26.453	26.090	EPSD	ICGC;COSMIC	19.028	Down-regulation
STE_STE20_PAKA_PAK1_ST	Q13153	PAK1	Q13153	PAK1	S21	P16L	16	Missense	distal	-5	no	26.453	26.352	EPSD	ICGC;COSMIC	19.028	Down-regulation
STE_STE20_PAKA_PAK1_ST	Q13153	PAK1	Q13153	PAK1	S21	T22N	22	Missense	proximal	1	no	26.453	26.135	EPSD	ICGC	19.028	Down-regulation
STE_STE20_PAKA_PAK1_ST	Q13153	PAK1	Q13153	PAK1	S57	D62N	62	Missense	distal	5	no	24.285	24.297	EPSD	ICGC;COSMIC	19.028	Up-regulation
STE_STE20_PAKA_PAK1_ST	Q13153	PAK1	Q13153	PAK1	S137	T136K	136	Missense	proximal	-1	no	18.967	19.035	EPSD	ICGC	19.028	Gain
STE_STE20_PAKA_PAK1_ST	Q13153	PAK1	Q13153	PAK1	S165	K162R	162	Missense	distal	-3	no	20.746	21.933	EPSD	ICGC;COSMIC	19.028	Up-regulation
STE_STE20_PAKA_PAK1_ST	Q13153	PAK1	Q13153	PAK1	S199	R193C	193	Missense	distal	-6	no	21.601	17.896	PhosphoSitePlus;EPSD	ICGC;COSMIC	19.028	Loss
STE_STE20_PAKA_PAK1_ST	Q13153	PAK1	Q13153	PAK1	T271	G277A	277	Missense	distal	6	no	19.302	18.954	EPSD	ICGC;COSMIC	19.028	Loss
STE_STE20_PAKA_PAK1_ST	Q13153	PAK1	Q13153	PAK1	T271	T271K	271	Missense	central	0	yes	19.302	0.000	EPSD	ICGC;COSMIC	19.028	Loss
STE_STE20_PAKA_PAK1_ST	Q13153	PAK1	Q13153	PAK1	T423	P416L	416	Missense	distal	-7	no	30.000	29.554	EPSD;PhosphoSitePlus	ICGC	19.028	Down-regulation
STE_STE20_PAKA_PAK1_ST	Q13153	PAK1	Q13153	PAK1	S528	P532L	532	Missense	distal	4	no	22.482	20.925	EPSD	ICGC;COSMIC	19.028	Down-regulation
STE_STE20_PAKA_PAK1_ST	O15143	ARPC1B	Q13153	PAK1	T21	R20H	20	Missense	proximal	-1	no	21.594	18.786	PhosphoSitePlus	ICGC;COSMIC;CCLE	19.028	Loss
STE_STE20_PAKA_PAK1_ST	O15143	ARPC1B	Q13153	PAK1	T21	A15T	15	Missense	distal	-6	no	21.594	21.520	PhosphoSitePlus	ICGC	19.028	Down-regulation
STE_STE20_PAKA_PAK1_ST	O15143	ARPC1B	Q13153	PAK1	T21	P27L	27	Missense	distal	6	no	21.594	21.618	PhosphoSitePlus	ICGC	19.028	Up-regulation
STE_STE20_PAKA_PAK1_ST	O15143	ARPC1B	Q13153	PAK1	T21	W16L	16	Missense	distal	-5	no	21.594	21.256	PhosphoSitePlus	ICGC	19.028	Down-regulation
STE_STE20_PAKA_PAK1_ST	O15143	ARPC1B	Q13153	PAK1	S170	A171S	171	Missense	proximal	1	no	21.863	21.948	EPSD	ICGC	19.028	Up-regulation
STE_STE20_PAKA_PAK1_ST	O15143	ARPC1B	Q13153	PAK1	S170	E177D	177	Missense	distal	7	no	21.863	21.878	EPSD	ICGC	19.028	Up-regulation
STE_STE20_PAKA_PAK1_ST	O15143	ARPC1B	Q13153	PAK1	S292	V287F	287	Missense	distal	-5	no	20.089	20.016	EPSD	ICGC	19.028	Down-regulation
STE_STE20_PAKA_PAK1_ST	O15143	ARPC1B	Q13153	PAK1	S292	A298T	298	Missense	distal	6	no	20.089	19.798	EPSD	ICGC;COSMIC	19.028	Down-regulation
STE_STE20_PAKA_PAK1_ST	O15143	ARPC1B	Q13153	PAK1	S310	N304T	304	Missense	distal	-6	no	21.527	22.137	EPSD	ICGC	19.028	Up-regulation
STE_STE20_PAKA_PAK1_ST	O15143	ARPC1B	Q13153	PAK1	S310	D306E	306	Missense	distal	-4	no	21.527	21.648	EPSD	ICGC	19.028	Up-regulation
STE_STE20_PAKA_PAK1_ST	O15143	ARPC1B	Q13153	PAK1	S311	N304T	304	Missense	distal	-7	no	22.081	22.715	EPSD	ICGC	19.028	Up-regulation
STE_STE20_PAKA_PAK1_ST	O15143	ARPC1B	Q13153	PAK1	S311	D306E	306	Missense	distal	-5	no	22.081	21.655	EPSD	ICGC	19.028	Down-regulation
STE_STE20_PAKA_PAK1_ST	P19086	GNAZ	Q13153	PAK1	S16	H22L	22	Missense	distal	6	no	28.087	28.180	PhosphoSitePlus	ICGC;COSMIC	19.028	Up-regulation
STE_STE20_PAKA_PAK1_ST	P19086	GNAZ	Q13153	PAK1	S16	R14L	14	Missense	proximal	-2	no	28.087	19.523	PhosphoSitePlus	ICGC	19.028	Down-regulation
STE_STE20_PAKA_PAK1_ST	P19086	GNAZ	Q13153	PAK1	S16	S16F	16	Missense	central	0	yes	28.087	0.000	PhosphoSitePlus	ICGC	19.028	Loss
STE_STE20_PAKA_PAK1_ST	P19086	GNAZ	Q13153	PAK1	S16	A13S	13	Missense	distal	-3	no	28.087	26.040	PhosphoSitePlus	ICGC;COSMIC	19.028	Down-regulation
STE_STE20_PAKA_PAK1_ST	P19086	GNAZ	Q13153	PAK1	S27	E33K	33	Missense	distal	6	no	20.135	20.450	EPSD	ICGC;COSMIC	19.028	Up-regulation
STE_STE20_PAKA_PAK1_ST	P19086	GNAZ	Q13153	PAK1	S27	H22L	22	Missense	distal	-5	no	20.135	20.479	EPSD	ICGC;COSMIC	19.028	Up-regulation
STE_STE20_PAKA_PAK1_ST	P19086	GNAZ	Q13153	PAK1	T182	R177C	177	Missense	distal	-5	no	22.092	22.848	EPSD	ICGC	19.028	Up-regulation
STE_STE20_PAKA_PAK1_ST	P19086	GNAZ	Q13153	PAK1	T182	K189N	189	Missense	distal	7	no	22.092	22.048	EPSD	ICGC	19.028	Down-regulation
STE_STE20_PAKA_PAK1_ST	P19086	GNAZ	Q13153	PAK1	T182	V186L	186	Missense	distal	4	no	22.092	21.266	EPSD	ICGC	19.028	Down-regulation
STE_STE20_PAKA_PAK1_ST	P04049	RAF1	Q13153	PAK1	S43	R40C	40	Missense	distal	-3	no	27.696	7.740	EPSD	ICGC;COSMIC	19.028	Loss
STE_STE20_PAKA_PAK1_ST	P04049	RAF1	Q13153	PAK1	S43	R41Q	41	Missense	proximal	-2	no	27.696	18.489	EPSD	ICGC	19.028	Loss
STE_STE20_PAKA_PAK1_ST	P04049	RAF1	Q13153	PAK1	S199	G205V	205	Missense	distal	6	no	19.449	19.423	EPSD	ICGC;COSMIC	19.028	Down-regulation
STE_STE20_PAKA_PAK1_ST	P04049	RAF1	Q13153	PAK1	S220	V226D	226	Missense	distal	6	no	19.644	19.347	EPSD	ICGC;COSMIC	19.028	Down-regulation
STE_STE20_PAKA_PAK1_ST	P04049	RAF1	Q13153	PAK1	S220	M224I	224	Missense	distal	4	no	19.644	19.439	EPSD	ICGC;COSMIC	19.028	Down-regulation
STE_STE20_PAKA_PAK1_ST	P04049	RAF1	Q13153	PAK1	S220	S220C	220	Missense	central	0	yes	19.644	0.000	EPSD	ICGC	19.028	Loss
STE_STE20_PAKA_PAK1_ST	P04049	RAF1	Q13153	PAK1	S220	R218L	218	Missense	proximal	-2	no	19.644	11.080	EPSD	ICGC;COSMIC	19.028	Loss
STE_STE20_PAKA_PAK1_ST	P04049	RAF1	Q13153	PAK1	S233	V226D	226	Missense	distal	-7	no	19.309	20.654	EPSD	ICGC;COSMIC	19.028	Up-regulation
STE_STE20_PAKA_PAK1_ST	Q13418	ILK	Q13153	PAK1	S232	D226E	226	Missense	distal	-6	no	25.033	25.930	EPSD	ICGC	19.028	Up-regulation
STE_STE20_PAKA_PAK1_ST	Q92934	BAD	Q13153	PAK1	S74	R72S	72	Missense	proximal	-2	no	20.464	12.311	EPSD;PhosphoSitePlus	ICGC	19.028	Loss
STE_STE20_PAKA_PAK1_ST	Q92934	BAD	Q13153	PAK1	S74	T80K	80	Missense	distal	6	no	20.464	20.949	EPSD;PhosphoSitePlus	ICGC	19.028	Up-regulation
STE_STE20_PAKA_PAK1_ST	Q92934	BAD	Q13153	PAK1	S74	S74G	74	Missense	central	0	yes	20.464	0.000	EPSD;PhosphoSitePlus	ICGC;COSMIC	19.028	Loss
STE_STE20_PAKA_PAK1_ST	Q92934	BAD	Q13153	PAK1	S75	R72S	72	Missense	distal	-3	no	25.891	17.220	PhosphoSitePlus;EPSD	ICGC	19.028	Loss
STE_STE20_PAKA_PAK1_ST	Q92934	BAD	Q13153	PAK1	S75	T80K	80	Missense	distal	5	no	25.891	25.899	PhosphoSitePlus;EPSD	ICGC	19.028	Up-regulation
STE_STE20_PAKA_PAK1_ST	Q92934	BAD	Q13153	PAK1	S75	S74G	74	Missense	proximal	-1	no	25.891	22.903	PhosphoSitePlus;EPSD	ICGC;COSMIC	19.028	Down-regulation
STE_STE20_PAKA_PAK1_ST	Q92934	BAD	Q13153	PAK1	S97	S99L	99	Missense	proximal	2	no	20.391	21.204	EPSD	ICGC	19.028	Up-regulation
STE_STE20_PAKA_PAK1_ST	Q92934	BAD	Q13153	PAK1	S97	R94W	94	Missense	distal	-3	no	20.391	12.830	EPSD	ICGC	19.028	Loss
STE_STE20_PAKA_PAK1_ST	Q92934	BAD	Q13153	PAK1	S99	S99L	99	Missense	central	0	yes	26.257	0.000	EPSD;PhosphoSitePlus	ICGC	19.028	Loss
STE_STE20_PAKA_PAK1_ST	Q92934	BAD	Q13153	PAK1	S99	R94W	94	Missense	distal	-5	no	26.257	27.386	EPSD;PhosphoSitePlus	ICGC	19.028	Up-regulation
STE_STE20_PAKA_PAK1_ST	Q92934	BAD	Q13153	PAK1	S118	R112S	112	Missense	distal	-6	no	30.333	28.323	EPSD;PhosphoSitePlus	ICGC	19.028	Down-regulation
STE_STE20_PAKA_PAK1_ST	Q92934	BAD	Q13153	PAK1	S144	R149L	149	Missense	distal	5	no	20.524	20.538	EPSD	ICGC;COSMIC	19.028	Up-regulation
STE_STE20_PAKA_PAK1_ST	Q92974	ARHGEF2	Q13153	PAK1	T103	N102K	102	Missense	proximal	-1	no	19.427	22.781	EPSD	ICGC	19.028	Up-regulation
STE_STE20_PAKA_PAK1_ST	Q92974	ARHGEF2	Q13153	PAK1	T103	A97T	97	Missense	distal	-6	no	19.427	19.354	EPSD	ICGC	19.028	Down-regulation
STE_STE20_PAKA_PAK1_ST	Q92974	ARHGEF2	Q13153	PAK1	S133	R139S	139	Missense	distal	6	no	23.146	23.411	EPSD	ICGC	19.028	Up-regulation
STE_STE20_PAKA_PAK1_ST	Q92974	ARHGEF2	Q13153	PAK1	S172	R169L	169	Missense	distal	-3	no	24.476	17.985	EPSD	ICGC;COSMIC	19.028	Loss
STE_STE20_PAKA_PAK1_ST	Q92974	ARHGEF2	Q13153	PAK1	S295	R301C	301	Missense	distal	6	no	24.588	25.223	EPSD	ICGC	19.028	Up-regulation
STE_STE20_PAKA_PAK1_ST	Q13233	MAP3K1	Q13153	PAK1	S133	D132H	132	Missense	proximal	-1	no	19.655	18.557	EPSD	ICGC	19.028	Loss
STE_STE20_PAKA_PAK1_ST	Q13233	MAP3K1	Q13153	PAK1	S133	A130E	130	Missense	distal	-3	no	19.655	11.300	EPSD	ICGC;COSMIC	19.028	Loss
STE_STE20_PAKA_PAK1_ST	Q13233	MAP3K1	Q13153	PAK1	S154	R147G	147	Missense	distal	-7	no	20.384	18.877	EPSD	ICGC;COSMIC	19.028	Loss
STE_STE20_PAKA_PAK1_ST	Q13233	MAP3K1	Q13153	PAK1	S250	R249C	249	Missense	proximal	-1	no	22.907	18.688	EPSD	ICGC;COSMIC;GDSC;CCLE	19.028	Loss
STE_STE20_PAKA_PAK1_ST	Q13233	MAP3K1	Q13153	PAK1	S250	P257Q	257	Missense	distal	7	no	22.907	22.736	EPSD	ICGC;COSMIC	19.028	Down-regulation
STE_STE20_PAKA_PAK1_ST	Q13233	MAP3K1	Q13153	PAK1	S250	R249H	249	Missense	proximal	-1	no	22.907	20.100	EPSD	ICGC;COSMIC;GDSC;CCLE	19.028	Down-regulation
STE_STE20_PAKA_PAK1_ST	Q13233	MAP3K1	Q13153	PAK1	S250	P253H	253	Missense	distal	3	no	22.907	20.940	EPSD	ICGC;COSMIC	19.028	Down-regulation
STE_STE20_PAKA_PAK1_ST	Q13233	MAP3K1	Q13153	PAK1	S264	P257Q	257	Missense	distal	-7	no	20.930	21.233	EPSD	ICGC;COSMIC	19.028	Up-regulation
STE_STE20_PAKA_PAK1_ST	Q13233	MAP3K1	Q13153	PAK1	S264	R260L	260	Missense	distal	-4	no	20.930	20.616	EPSD	ICGC	19.028	Down-regulation
STE_STE20_PAKA_PAK1_ST	Q13233	MAP3K1	Q13153	PAK1	S264	G259V	259	Missense	distal	-5	no	20.930	20.517	EPSD	ICGC	19.028	Down-regulation
STE_STE20_PAKA_PAK1_ST	Q13233	MAP3K1	Q13153	PAK1	S264	V262G	262	Missense	proximal	-2	no	20.930	16.925	EPSD	ICGC;COSMIC	19.028	Loss
STE_STE20_PAKA_PAK1_ST	Q13233	MAP3K1	Q13153	PAK1	S264	G259C	259	Missense	distal	-5	no	20.930	20.741	EPSD	ICGC;COSMIC	19.028	Down-regulation
STE_STE20_PAKA_PAK1_ST	Q13233	MAP3K1	Q13153	PAK1	S264	R270S	270	Missense	distal	6	no	20.930	21.195	EPSD	ICGC;COSMIC	19.028	Up-regulation
STE_STE20_PAKA_PAK1_ST	Q13233	MAP3K1	Q13153	PAK1	S264	V269E	269	Missense	distal	5	no	20.930	20.916	EPSD	ICGC;COSMIC	19.028	Down-regulation
STE_STE20_PAKA_PAK1_ST	Q13233	MAP3K1	Q13153	PAK1	S264	R260S	260	Missense	distal	-4	no	20.930	20.463	EPSD	ICGC;COSMIC	19.028	Down-regulation
STE_STE20_PAKA_PAK1_ST	Q13233	MAP3K1	Q13153	PAK1	S266	R260L	260	Missense	distal	-6	no	19.092	16.871	EPSD	ICGC	19.028	Loss
STE_STE20_PAKA_PAK1_ST	Q13233	MAP3K1	Q13153	PAK1	S266	G259V	259	Missense	distal	-7	no	19.092	18.424	EPSD	ICGC	19.028	Loss
STE_STE20_PAKA_PAK1_ST	Q13233	MAP3K1	Q13153	PAK1	S266	V262G	262	Missense	distal	-4	no	19.092	18.764	EPSD	ICGC;COSMIC	19.028	Loss
STE_STE20_PAKA_PAK1_ST	Q13233	MAP3K1	Q13153	PAK1	S266	G259C	259	Missense	distal	-7	no	19.092	18.332	EPSD	ICGC;COSMIC	19.028	Loss
STE_STE20_PAKA_PAK1_ST	Q13233	MAP3K1	Q13153	PAK1	S266	R270S	270	Missense	distal	4	no	19.092	19.696	EPSD	ICGC;COSMIC	19.028	Up-regulation
STE_STE20_PAKA_PAK1_ST	Q13233	MAP3K1	Q13153	PAK1	S266	V269E	269	Missense	distal	3	no	19.092	17.867	EPSD	ICGC;COSMIC	19.028	Loss
STE_STE20_PAKA_PAK1_ST	Q13233	MAP3K1	Q13153	PAK1	S266	R260S	260	Missense	distal	-6	no	19.092	17.082	EPSD	ICGC;COSMIC	19.028	Loss
STE_STE20_PAKA_PAK1_ST	Q13233	MAP3K1	Q13153	PAK1	S275	G282V	282	Missense	distal	7	no	28.994	28.945	EPSD	ICGC	19.028	Down-regulation
STE_STE20_PAKA_PAK1_ST	Q13233	MAP3K1	Q13153	PAK1	S275	S275F	275	Missense	central	0	yes	28.994	0.000	EPSD	ICGC;COSMIC	19.028	Loss
STE_STE20_PAKA_PAK1_ST	Q13233	MAP3K1	Q13153	PAK1	S275	R270S	270	Missense	distal	-5	no	28.994	29.024	EPSD	ICGC;COSMIC	19.028	Up-regulation
STE_STE20_PAKA_PAK1_ST	Q13233	MAP3K1	Q13153	PAK1	S275	V269E	269	Missense	distal	-6	no	28.994	29.832	EPSD	ICGC;COSMIC	19.028	Up-regulation
STE_STE20_PAKA_PAK1_ST	Q13233	MAP3K1	Q13153	PAK1	S292	P293A	293	Missense	proximal	1	no	19.861	19.892	EPSD	ICGC;COSMIC	19.028	Up-regulation
STE_STE20_PAKA_PAK1_ST	Q13233	MAP3K1	Q13153	PAK1	S292	G295V	295	Missense	distal	3	no	19.861	18.574	EPSD	ICGC	19.028	Loss
STE_STE20_PAKA_PAK1_ST	Q13233	MAP3K1	Q13153	PAK1	S292	S292P	292	Missense	central	0	yes	19.861	0.000	EPSD	ICGC	19.028	Loss
STE_STE20_PAKA_PAK1_ST	Q13233	MAP3K1	Q13153	PAK1	S292	R289I	289	Missense	distal	-3	no	19.861	4.394	EPSD	ICGC;COSMIC	19.028	Loss
STE_STE20_PAKA_PAK1_ST	Q13233	MAP3K1	Q13153	PAK1	S297	G295V	295	Missense	proximal	-2	no	16.006	20.011	EPSD	ICGC	19.028	Gain
STE_STE20_PAKA_PAK1_ST	Q13233	MAP3K1	Q13153	PAK1	S397	R395S	395	Missense	proximal	-2	no	23.250	15.098	EPSD	ICGC	19.028	Loss
STE_STE20_PAKA_PAK1_ST	Q13233	MAP3K1	Q13153	PAK1	S398	R395S	395	Missense	distal	-3	no	24.830	16.159	EPSD	ICGC	19.028	Loss
STE_STE20_PAKA_PAK1_ST	Q13233	MAP3K1	Q13153	PAK1	S398	R405L	405	Missense	distal	7	no	24.830	24.978	EPSD	ICGC	19.028	Up-regulation
STE_STE20_PAKA_PAK1_ST	Q13233	MAP3K1	Q13153	PAK1	S1026	K1024T	1024	Missense	proximal	-2	no	26.418	25.593	EPSD	ICGC;GDSC;CCLE	19.028	Down-regulation
STE_STE20_PAKA_PAK1_ST	Q13233	MAP3K1	Q13153	PAK1	S1397	G1401S	1401	Missense	distal	4	no	19.572	18.364	EPSD	ICGC	19.028	Loss
STE_STE20_PAKA_PAK1_ST	Q13233	MAP3K1	Q13153	PAK1	S1397	G1399E	1399	Missense	proximal	2	no	19.572	18.452	EPSD	ICGC;COSMIC	19.028	Loss
STE_STE20_PAKA_PAK1_ST	Q13233	MAP3K1	Q13153	PAK1	S1397	A1391S	1391	Missense	distal	-6	no	19.572	18.515	EPSD	ICGC;COSMIC	19.028	Loss
STE_STE20_PAKA_PAK1_ST	Q99426	TBCB	Q13153	PAK1	S29	R30L	30	Missense	proximal	1	no	25.813	25.581	EPSD	ICGC	19.028	Down-regulation
STE_STE20_PAKA_PAK1_ST	Q99426	TBCB	Q13153	PAK1	T33	R30L	30	Missense	distal	-3	no	26.407	19.916	EPSD	ICGC	19.028	Down-regulation
STE_STE20_PAKA_PAK1_ST	Q99426	TBCB	Q13153	PAK1	S65	D68V	68	Missense	distal	3	no	21.424	21.438	EPSD;PhosphoSitePlus	ICGC;COSMIC	19.028	Up-regulation
STE_STE20_PAKA_PAK1_ST	Q99426	TBCB	Q13153	PAK1	S65	D60V	60	Missense	distal	-5	no	21.424	21.444	EPSD;PhosphoSitePlus	ICGC;COSMIC	19.028	Up-regulation
STE_STE20_PAKA_PAK1_ST	Q99426	TBCB	Q13153	PAK1	S65	E70D	70	Missense	distal	5	no	21.424	21.431	EPSD;PhosphoSitePlus	ICGC;COSMIC	19.028	Up-regulation
STE_STE20_PAKA_PAK1_ST	Q99426	TBCB	Q13153	PAK1	S65	K62T	62	Missense	distal	-3	no	21.424	16.354	EPSD;PhosphoSitePlus	ICGC	19.028	Loss
STE_STE20_PAKA_PAK1_ST	Q99426	TBCB	Q13153	PAK1	S110	D115Y	115	Missense	distal	5	no	19.508	19.531	EPSD	ICGC;COSMIC	19.028	Up-regulation
STE_STE20_PAKA_PAK1_ST	Q99426	TBCB	Q13153	PAK1	S128	Y133N	133	Missense	distal	5	no	20.192	20.181	PhosphoSitePlus;EPSD	ICGC	19.028	Down-regulation
STE_STE20_PAKA_PAK1_ST	Q99426	TBCB	Q13153	PAK1	S128	R122L	122	Missense	distal	-6	no	20.192	17.971	PhosphoSitePlus;EPSD	ICGC	19.028	Loss
STE_STE20_PAKA_PAK1_ST	Q99661	KIF2C	Q13153	PAK1	S111	R113H	113	Missense	proximal	2	no	26.002	26.321	EPSD;PhosphoSitePlus	ICGC	19.028	Up-regulation
STE_STE20_PAKA_PAK1_ST	Q99661	KIF2C	Q13153	PAK1	S111	R113L	113	Missense	proximal	2	no	26.002	27.201	EPSD;PhosphoSitePlus	ICGC	19.028	Up-regulation
STE_STE20_PAKA_PAK1_ST	Q99661	KIF2C	Q13153	PAK1	T116	R113H	113	Missense	distal	-3	no	25.853	19.782	EPSD	ICGC	19.028	Down-regulation
STE_STE20_PAKA_PAK1_ST	Q99661	KIF2C	Q13153	PAK1	T116	R113L	113	Missense	distal	-3	no	25.853	19.363	EPSD	ICGC	19.028	Down-regulation
STE_STE20_PAKA_PAK1_ST	Q99661	KIF2C	Q13153	PAK1	S144	V145F	145	Missense	proximal	1	no	22.791	23.128	EPSD	ICGC	19.028	Up-regulation
STE_STE20_PAKA_PAK1_ST	P18669	PGAM1	Q13153	PAK1	S23	Y26H	26	Missense	distal	3	no	23.434	20.068	PhosphoSitePlus;EPSD	ICGC	19.028	Down-regulation
STE_STE20_PAKA_PAK1_ST	P18669	PGAM1	Q13153	PAK1	S118	Y119C	119	Missense	proximal	1	no	23.471	23.519	EPSD;PhosphoSitePlus	ICGC;COSMIC	19.028	Up-regulation
STE_STE20_PAKA_PAK1_ST	P78545	ELF3	Q13153	PAK1	S207	R205W	205	Missense	proximal	-2	no	22.411	9.472	PhosphoSitePlus	ICGC;COSMIC;CCLE	19.028	Loss
STE_STE20_PAKA_PAK1_ST	P78545	ELF3	Q13153	PAK1	S207	R205L	205	Missense	proximal	-2	no	22.411	13.847	PhosphoSitePlus	ICGC;COSMIC	19.028	Loss
STE_STE20_PAKA_PAK1_ST	P78545	ELF3	Q13153	PAK1	S207	S209F	209	Missense	proximal	2	no	22.411	22.495	PhosphoSitePlus	ICGC	19.028	Up-regulation
STE_STE20_PAKA_PAK1_ST	P78545	ELF3	Q13153	PAK1	S207	G214E	214	Missense	distal	7	no	22.411	22.311	PhosphoSitePlus	ICGC	19.028	Down-regulation
STE_STE20_PAKA_PAK1_ST	P78545	ELF3	Q13153	PAK1	S254	C260F	260	Missense	distal	6	no	24.714	24.720	EPSD	ICGC	19.028	Up-regulation
STE_STE20_PAKA_PAK1_ST	P46108	CRK	Q13153	PAK1	S41	G45W	45	Missense	distal	4	no	23.881	24.187	PhosphoSitePlus	ICGC;COSMIC	19.028	Up-regulation
STE_STE20_PAKA_PAK1_ST	P46108	CRK	Q13153	PAK1	S41	R38L	38	Missense	distal	-3	no	23.881	17.391	PhosphoSitePlus	ICGC;COSMIC	19.028	Loss
STE_STE20_PAKA_PAK1_ST	P46108	CRK	Q13153	PAK1	S83	G81R	81	Missense	proximal	-2	no	13.119	22.682	EPSD	ICGC;COSMIC	19.028	Gain
STE_STE20_PAKA_PAK1_ST	P46108	CRK	Q13153	PAK1	S194	E188K	188	Missense	distal	-6	no	20.158	19.002	EPSD	ICGC;COSMIC	19.028	Loss
STE_STE20_PAKA_PAK1_ST	P35222	CTNNB1	Q13153	PAK1	T332	T332N	332	Missense	central	0	yes	20.339	0.000	EPSD	ICGC;COSMIC	19.028	Loss
STE_STE20_PAKA_PAK1_ST	Q14247	CTTN	Q13153	PAK1	S117	Q114H	114	Missense	distal	-3	no	17.252	19.904	EPSD	ICGC	19.028	Gain
STE_STE20_PAKA_PAK1_ST	Q14247	CTTN	Q13153	PAK1	S155	G160S	160	Missense	distal	5	no	21.265	21.234	EPSD	ICGC;COSMIC	19.028	Down-regulation
STE_STE20_PAKA_PAK1_ST	Q14247	CTTN	Q13153	PAK1	S156	G160S	160	Missense	distal	4	no	20.434	19.226	EPSD	ICGC;COSMIC	19.028	Down-regulation
STE_STE20_PAKA_PAK1_ST	Q14247	CTTN	Q13153	PAK1	S187	G180V	180	Missense	distal	-7	no	20.831	20.163	EPSD	ICGC;COSMIC	19.028	Down-regulation
STE_STE20_PAKA_PAK1_ST	Q14247	CTTN	Q13153	PAK1	S187	S187P	187	Missense	central	0	yes	20.831	0.000	EPSD	ICGC	19.028	Loss
STE_STE20_PAKA_PAK1_ST	Q14247	CTTN	Q13153	PAK1	S192	G196D	196	Missense	distal	4	no	22.007	21.549	EPSD	ICGC;COSMIC	19.028	Down-regulation
STE_STE20_PAKA_PAK1_ST	Q14247	CTTN	Q13153	PAK1	S192	S187P	187	Missense	distal	-5	no	22.007	22.869	EPSD	ICGC	19.028	Up-regulation
STE_STE20_PAKA_PAK1_ST	Q14247	CTTN	Q13153	PAK1	S192	G197D	197	Missense	distal	5	no	22.007	21.984	EPSD	ICGC;COSMIC	19.028	Down-regulation
STE_STE20_PAKA_PAK1_ST	Q14247	CTTN	Q13153	PAK1	S224	G231R	231	Missense	distal	7	no	20.281	20.114	EPSD	ICGC	19.028	Down-regulation
STE_STE20_PAKA_PAK1_ST	Q14247	CTTN	Q13153	PAK1	T267	G274V	274	Missense	distal	7	no	20.260	20.211	EPSD	ICGC;COSMIC	19.028	Down-regulation
STE_STE20_PAKA_PAK1_ST	Q14247	CTTN	Q13153	PAK1	T267	G271C	271	Missense	distal	4	no	20.260	20.441	EPSD	ICGC	19.028	Up-regulation
STE_STE20_PAKA_PAK1_ST	Q14247	CTTN	Q13153	PAK1	T267	K272E	272	Missense	distal	5	no	20.260	20.253	EPSD	ICGC;COSMIC	19.028	Down-regulation
STE_STE20_PAKA_PAK1_ST	Q14247	CTTN	Q13153	PAK1	S298	G305V	305	Missense	distal	7	no	20.933	20.884	EPSD	ICGC	19.028	Down-regulation
STE_STE20_PAKA_PAK1_ST	Q14247	CTTN	Q13153	PAK1	T399	T401M	401	Missense	proximal	2	no	20.621	22.385	EPSD	ICGC;COSMIC	19.028	Up-regulation
STE_STE20_PAKA_PAK1_ST	Q14247	CTTN	Q13153	PAK1	T399	T401A	401	Missense	proximal	2	no	20.621	22.264	EPSD	ICGC	19.028	Up-regulation
STE_STE20_PAKA_PAK1_ST	Q14247	CTTN	Q13153	PAK1	T399	S405L	405	Missense	distal	6	no	20.621	20.893	EPSD	ICGC;COSMIC;GDSC	19.028	Up-regulation
STE_STE20_PAKA_PAK1_ST	Q14247	CTTN	Q13153	PAK1	T401	T401M	401	Missense	central	0	yes	19.925	0.000	EPSD	ICGC;COSMIC	19.028	Loss
STE_STE20_PAKA_PAK1_ST	Q14247	CTTN	Q13153	PAK1	T401	T401A	401	Missense	central	0	yes	19.925	0.000	EPSD	ICGC	19.028	Loss
STE_STE20_PAKA_PAK1_ST	Q14247	CTTN	Q13153	PAK1	T401	S405L	405	Missense	distal	4	no	19.925	20.718	EPSD	ICGC;COSMIC;GDSC	19.028	Up-regulation
STE_STE20_PAKA_PAK1_ST	Q14247	CTTN	Q13153	PAK1	T401	A407T	407	Missense	distal	6	no	19.925	19.634	EPSD	ICGC;COSMIC	19.028	Down-regulation
STE_STE20_PAKA_PAK1_ST	Q14247	CTTN	Q13153	PAK1	S405	E412K	412	Missense	distal	7	no	19.139	19.194	EPSD;PhosphoSitePlus	ICGC;COSMIC	19.028	Up-regulation
STE_STE20_PAKA_PAK1_ST	Q14247	CTTN	Q13153	PAK1	S405	T401M	401	Missense	distal	-4	no	19.139	18.432	EPSD;PhosphoSitePlus	ICGC;COSMIC	19.028	Loss
STE_STE20_PAKA_PAK1_ST	Q14247	CTTN	Q13153	PAK1	S405	T401A	401	Missense	distal	-4	no	19.139	18.722	EPSD;PhosphoSitePlus	ICGC	19.028	Loss
STE_STE20_PAKA_PAK1_ST	Q14247	CTTN	Q13153	PAK1	S405	S405L	405	Missense	central	0	yes	19.139	0.000	EPSD;PhosphoSitePlus	ICGC;COSMIC;GDSC	19.028	Loss
STE_STE20_PAKA_PAK1_ST	Q14247	CTTN	Q13153	PAK1	S405	A407T	407	Missense	proximal	2	no	19.139	17.496	EPSD;PhosphoSitePlus	ICGC;COSMIC	19.028	Loss
STE_STE20_PAKA_PAK1_ST	Q14247	CTTN	Q13153	PAK1	S417	E412K	412	Missense	distal	-5	no	21.187	21.247	EPSD	ICGC;COSMIC	19.028	Up-regulation
STE_STE20_PAKA_PAK1_ST	Q14247	CTTN	Q13153	PAK1	S417	L415P	415	Missense	proximal	-2	no	21.187	26.227	EPSD	ICGC	19.028	Up-regulation
STE_STE20_PAKA_PAK1_ST	Q14247	CTTN	Q13153	PAK1	S417	A424V	424	Missense	distal	7	no	21.187	21.192	EPSD	ICGC;COSMIC;GDSC	19.028	Up-regulation
STE_STE20_PAKA_PAK1_ST	Q14247	CTTN	Q13153	PAK1	S418	E412K	412	Missense	distal	-6	no	22.486	21.330	EPSD;PhosphoSitePlus	ICGC;COSMIC	19.028	Down-regulation
STE_STE20_PAKA_PAK1_ST	Q14247	CTTN	Q13153	PAK1	S418	L415P	415	Missense	distal	-3	no	22.486	23.293	EPSD;PhosphoSitePlus	ICGC	19.028	Up-regulation
STE_STE20_PAKA_PAK1_ST	Q14247	CTTN	Q13153	PAK1	S418	A424V	424	Missense	distal	6	no	22.486	22.807	EPSD;PhosphoSitePlus	ICGC;COSMIC;GDSC	19.028	Up-regulation
STE_STE20_PAKA_PAK1_ST	P49023	PXN	Q13153	PAK1	S320	S322L	322	Missense	proximal	2	no	18.941	19.755	EPSD	ICGC;COSMIC	19.028	Gain
STE_STE20_PAKA_PAK1_ST	P49023	PXN	Q13153	PAK1	S533	H526Q	526	Missense	distal	-7	no	22.668	23.495	EPSD	ICGC	19.028	Up-regulation
STE_STE20_PAKA_PAK1_ST	Q9Y2X7	GIT1	Q13153	PAK1	S46	R39W	39	Missense	distal	-7	no	22.067	20.185	EPSD	ICGC;COSMIC	19.028	Down-regulation
STE_STE20_PAKA_PAK1_ST	Q9Y2X7	GIT1	Q13153	PAK1	S46	R43C	43	Missense	distal	-3	no	22.067	2.111	EPSD	ICGC;COSMIC	19.028	Loss
STE_STE20_PAKA_PAK1_ST	Q9Y2X7	GIT1	Q13153	PAK1	S46	R43H	43	Missense	distal	-3	no	22.067	15.995	EPSD	ICGC;CCLE	19.028	Loss
STE_STE20_PAKA_PAK1_ST	Q9Y2X7	GIT1	Q13153	PAK1	S46	R52C	52	Missense	distal	6	no	22.067	22.702	EPSD	ICGC	19.028	Up-regulation
STE_STE20_PAKA_PAK1_ST	Q9Y2X7	GIT1	Q13153	PAK1	S46	R39L	39	Missense	distal	-7	no	22.067	20.794	EPSD	ICGC;COSMIC	19.028	Down-regulation
STE_STE20_PAKA_PAK1_ST	Q9Y2X7	GIT1	Q13153	PAK1	S54	T59M	59	Missense	distal	5	no	19.375	19.404	EPSD	ICGC	19.028	Up-regulation
STE_STE20_PAKA_PAK1_ST	Q9Y2X7	GIT1	Q13153	PAK1	S54	R52C	52	Missense	proximal	-2	no	19.375	6.654	EPSD	ICGC	19.028	Loss
STE_STE20_PAKA_PAK1_ST	Q9Y2X7	GIT1	Q13153	PAK1	S375	R372W	372	Missense	distal	-3	no	20.414	12.854	EPSD	ICGC	19.028	Loss
STE_STE20_PAKA_PAK1_ST	Q9Y2X7	GIT1	Q13153	PAK1	S375	R372Q	372	Missense	distal	-3	no	20.414	11.690	EPSD	ICGC;COSMIC	19.028	Loss
STE_STE20_PAKA_PAK1_ST	Q9Y2X7	GIT1	Q13153	PAK1	S375	D382N	382	Missense	distal	7	no	20.414	20.410	EPSD	ICGC	19.028	Down-regulation
STE_STE20_PAKA_PAK1_ST	Q9Y2X7	GIT1	Q13153	PAK1	S388	S385R	385	Missense	distal	-3	no	10.694	19.365	EPSD	ICGC	19.028	Gain
STE_STE20_PAKA_PAK1_ST	Q9Y2X7	GIT1	Q13153	PAK1	T400	R404W	404	Missense	distal	4	no	17.971	20.089	EPSD	ICGC;COSMIC	19.028	Gain
STE_STE20_PAKA_PAK1_ST	Q9Y2X7	GIT1	Q13153	PAK1	S410	R404W	404	Missense	distal	-6	no	20.629	18.005	EPSD	ICGC;COSMIC	19.028	Loss
STE_STE20_PAKA_PAK1_ST	Q9Y2X7	GIT1	Q13153	PAK1	S410	R407W	407	Missense	distal	-3	no	20.629	13.068	EPSD	ICGC;COSMIC	19.028	Loss
STE_STE20_PAKA_PAK1_ST	Q9Y2X7	GIT1	Q13153	PAK1	S410	R407L	407	Missense	distal	-3	no	20.629	14.138	EPSD	ICGC;COSMIC	19.028	Loss
STE_STE20_PAKA_PAK1_ST	Q9Y2X7	GIT1	Q13153	PAK1	S508	R504C	504	Missense	distal	-4	no	21.055	20.096	PhosphoSitePlus;EPSD	ICGC;COSMIC	19.028	Down-regulation
STE_STE20_PAKA_PAK1_ST	Q9Y2X7	GIT1	Q13153	PAK1	S508	R504H	504	Missense	distal	-4	no	21.055	20.621	PhosphoSitePlus;EPSD	ICGC;COSMIC	19.028	Down-regulation
STE_STE20_PAKA_PAK1_ST	Q9Y2X7	GIT1	Q13153	PAK1	S536	D542N	542	Missense	distal	6	no	20.974	21.119	EPSD	ICGC;COSMIC	19.028	Up-regulation
STE_STE20_PAKA_PAK1_ST	Q9Y2X7	GIT1	Q13153	PAK1	S536	R530W	530	Missense	distal	-6	no	20.974	18.351	EPSD	ICGC;COSMIC	19.028	Loss
STE_STE20_PAKA_PAK1_ST	Q9Y2X7	GIT1	Q13153	PAK1	S536	A543T	543	Missense	distal	7	no	20.974	20.680	EPSD	ICGC;COSMIC	19.028	Down-regulation
STE_STE20_PAKA_PAK1_ST	Q9Y2X7	GIT1	Q13153	PAK1	S536	T529M	529	Missense	distal	-7	no	20.974	19.374	EPSD	ICGC;COSMIC	19.028	Down-regulation
STE_STE20_PAKA_PAK1_ST	Q9Y2X7	GIT1	Q13153	PAK1	S546	A543T	543	Missense	distal	-3	no	18.924	19.291	EPSD	ICGC;COSMIC	19.028	Gain
STE_STE20_PAKA_PAK1_ST	Q9Y2X7	GIT1	Q13153	PAK1	T568	V565A	565	Missense	distal	-3	no	12.613	19.875	EPSD	ICGC;COSMIC	19.028	Gain
STE_STE20_PAKA_PAK1_ST	Q9Y2X7	GIT1	Q13153	PAK1	S571	P572L	572	Missense	proximal	1	no	19.364	19.651	EPSD	ICGC;COSMIC	19.028	Up-regulation
STE_STE20_PAKA_PAK1_ST	Q9Y2X7	GIT1	Q13153	PAK1	S571	P572S	572	Missense	proximal	1	no	19.364	19.481	EPSD	ICGC;COSMIC	19.028	Up-regulation
STE_STE20_PAKA_PAK1_ST	Q9Y2X7	GIT1	Q13153	PAK1	S571	V565A	565	Missense	distal	-6	no	19.364	20.151	EPSD	ICGC;COSMIC	19.028	Up-regulation
STE_STE20_PAKA_PAK1_ST	Q9Y2X7	GIT1	Q13153	PAK1	S592	E599D	599	Missense	distal	7	no	21.563	21.579	EPSD	ICGC	19.028	Up-regulation
STE_STE20_PAKA_PAK1_ST	Q9Y2X7	GIT1	Q13153	PAK1	S700	A707T	707	Missense	distal	7	no	21.820	21.525	EPSD;PhosphoSitePlus	ICGC;COSMIC	19.028	Down-regulation
STE_STE20_PAKA_PAK1_ST	Q9Y2X7	GIT1	Q13153	PAK1	S700	R699W	699	Missense	proximal	-1	no	21.820	18.199	EPSD;PhosphoSitePlus	ICGC;COSMIC	19.028	Loss
STE_STE20_PAKA_PAK1_ST	P53350	PLK1	Q13153	PAK1	S137	E140Q	140	Missense	distal	3	no	26.095	26.521	EPSD	ICGC;COSMIC	19.028	Up-regulation
STE_STE20_PAKA_PAK1_ST	P53350	PLK1	Q13153	PAK1	S224	E221K	221	Missense	distal	-3	no	10.379	24.171	EPSD	ICGC;COSMIC	19.028	Gain
STE_STE20_PAKA_PAK1_ST	P53350	PLK1	Q13153	PAK1	S326	D333Y	333	Missense	distal	7	no	24.459	24.713	EPSD	ICGC	19.028	Up-regulation
STE_STE20_PAKA_PAK1_ST	P53350	PLK1	Q13153	PAK1	S326	I327V	327	Missense	proximal	1	no	24.459	24.136	EPSD	ICGC;COSMIC	19.028	Down-regulation
STE_STE20_PAKA_PAK1_ST	P53350	PLK1	Q13153	PAK1	T341	T341I	341	Missense	central	0	yes	23.847	0.000	EPSD	ICGC;COSMIC	19.028	Loss
STE_STE20_PAKA_PAK1_ST	P53350	PLK1	Q13153	PAK1	S565	R563H	563	Missense	proximal	-2	no	24.734	19.320	EPSD	ICGC;COSMIC	19.028	Down-regulation
STE_STE20_PAKA_PAK1_ST	P53350	PLK1	Q13153	PAK1	S565	R563C	563	Missense	proximal	-2	no	24.734	12.013	EPSD	ICGC;COSMIC	19.028	Loss
STE_STE20_PAKA_PAK1_ST	P53350	PLK1	Q13153	PAK1	S565	R560C	560	Missense	distal	-5	no	24.734	25.489	EPSD	ICGC	19.028	Up-regulation
STE_STE20_PAKA_PAK1_ST	P53350	PLK1	Q13153	PAK1	S565	S565I	565	Missense	central	0	yes	24.734	0.000	EPSD	ICGC;COSMIC	19.028	Loss
STE_STE20_PAKA_PAK1_ST	P53350	PLK1	Q13153	PAK1	S565	Y562D	562	Missense	distal	-3	no	24.734	23.545	EPSD	ICGC	19.028	Down-regulation
STE_STE20_PAKA_PAK1_ST	P24844	MYL9	Q13153	PAK1	T11	R14W	14	Missense	distal	3	no	17.541	19.944	EPSD	ICGC;COSMIC	19.028	Gain
STE_STE20_PAKA_PAK1_ST	P24844	MYL9	Q13153	PAK1	T19	R14W	14	Missense	distal	-5	no	18.846	19.975	EPSD	ICGC;COSMIC	19.028	Gain
STE_STE20_PAKA_PAK1_ST	P24844	MYL9	Q13153	PAK1	S20	R17L	17	Missense	distal	-3	no	23.883	17.392	PhosphoSitePlus	ICGC;COSMIC	19.028	Loss
STE_STE20_PAKA_PAK1_ST	P24844	MYL9	Q13153	PAK1	S20	R14W	14	Missense	distal	-6	no	23.883	21.259	PhosphoSitePlus	ICGC;COSMIC	19.028	Down-regulation
STE_STE20_PAKA_PAK1_ST	P24844	MYL9	Q13153	PAK1	T135	F134L	134	Missense	proximal	-1	no	20.439	20.590	EPSD	ICGC;COSMIC	19.028	Up-regulation
STE_STE20_PAKA_PAK1_ST	P21333	FLNA	Q13153	PAK1	S72	R76W	76	Missense	distal	4	no	18.081	20.199	EPSD	ICGC;COSMIC	19.028	Gain
STE_STE20_PAKA_PAK1_ST	P21333	FLNA	Q13153	PAK1	S204	P211H	211	Missense	distal	7	no	19.434	19.315	EPSD	ICGC	19.028	Down-regulation
STE_STE20_PAKA_PAK1_ST	P21333	FLNA	Q13153	PAK1	T341	Y346H	346	Missense	distal	5	no	19.929	19.909	EPSD	ICGC;COSMIC	19.028	Down-regulation
STE_STE20_PAKA_PAK1_ST	P21333	FLNA	Q13153	PAK1	T341	R340C	340	Missense	proximal	-1	no	19.929	15.709	EPSD	ICGC;COSMIC	19.028	Loss
STE_STE20_PAKA_PAK1_ST	P21333	FLNA	Q13153	PAK1	T341	F342L	342	Missense	proximal	1	no	19.929	19.838	EPSD	ICGC;COSMIC	19.028	Down-regulation
STE_STE20_PAKA_PAK1_ST	P21333	FLNA	Q13153	PAK1	T341	V347I	347	Missense	distal	6	no	19.929	19.807	EPSD	ICGC;COSMIC	19.028	Down-regulation
STE_STE20_PAKA_PAK1_ST	P21333	FLNA	Q13153	PAK1	S343	Y346H	346	Missense	distal	3	no	28.456	25.090	EPSD	ICGC;COSMIC	19.028	Down-regulation
STE_STE20_PAKA_PAK1_ST	P21333	FLNA	Q13153	PAK1	S343	R340C	340	Missense	distal	-3	no	28.456	8.501	EPSD	ICGC;COSMIC	19.028	Loss
STE_STE20_PAKA_PAK1_ST	P21333	FLNA	Q13153	PAK1	S343	F342L	342	Missense	proximal	-1	no	28.456	28.607	EPSD	ICGC;COSMIC	19.028	Up-regulation
STE_STE20_PAKA_PAK1_ST	P21333	FLNA	Q13153	PAK1	S343	V347I	347	Missense	distal	4	no	28.456	28.354	EPSD	ICGC;COSMIC	19.028	Down-regulation
STE_STE20_PAKA_PAK1_ST	P21333	FLNA	Q13153	PAK1	S440	D439N	439	Missense	proximal	-1	no	20.064	17.887	EPSD	ICGC	19.028	Loss
STE_STE20_PAKA_PAK1_ST	P21333	FLNA	Q13153	PAK1	S440	Q447K	447	Missense	distal	7	no	20.064	20.190	EPSD	ICGC;COSMIC	19.028	Up-regulation
STE_STE20_PAKA_PAK1_ST	P21333	FLNA	Q13153	PAK1	T507	G511V	511	Missense	distal	4	no	18.633	19.045	EPSD	ICGC	19.028	Gain
STE_STE20_PAKA_PAK1_ST	P21333	FLNA	Q13153	PAK1	T507	V505M	505	Missense	proximal	-2	no	18.633	19.954	EPSD	ICGC	19.028	Gain
STE_STE20_PAKA_PAK1_ST	P21333	FLNA	Q13153	PAK1	T572	G571A	571	Missense	proximal	-1	no	19.568	20.006	EPSD	ICGC;COSMIC	19.028	Up-regulation
STE_STE20_PAKA_PAK1_ST	P21333	FLNA	Q13153	PAK1	T934	N931K	931	Missense	distal	-3	no	13.793	21.637	EPSD	ICGC	19.028	Gain
STE_STE20_PAKA_PAK1_ST	P21333	FLNA	Q13153	PAK1	T1286	H1292R	1292	Missense	distal	6	no	19.276	18.832	EPSD	ICGC;COSMIC	19.028	Loss
STE_STE20_PAKA_PAK1_ST	P21333	FLNA	Q13153	PAK1	T1286	V1293I	1293	Missense	distal	7	no	19.276	19.278	EPSD	ICGC;COSMIC	19.028	Up-regulation
STE_STE20_PAKA_PAK1_ST	P21333	FLNA	Q13153	PAK1	T1305	N1299K	1299	Missense	distal	-6	no	19.455	19.034	EPSD	ICGC	19.028	Down-regulation
STE_STE20_PAKA_PAK1_ST	P21333	FLNA	Q13153	PAK1	T1305	G1302C	1302	Missense	distal	-3	no	19.455	7.376	EPSD	ICGC;COSMIC	19.028	Loss
STE_STE20_PAKA_PAK1_ST	P21333	FLNA	Q13153	PAK1	T1475	Q1472K	1472	Missense	distal	-3	no	12.760	20.297	EPSD	ICGC	19.028	Gain
STE_STE20_PAKA_PAK1_ST	P21333	FLNA	Q13153	PAK1	S1522	P1518T	1518	Missense	distal	-4	no	18.716	19.282	EPSD	ICGC	19.028	Gain
STE_STE20_PAKA_PAK1_ST	P21333	FLNA	Q13153	PAK1	T1617	G1623V	1623	Missense	distal	6	no	20.973	20.947	EPSD	ICGC;COSMIC	19.028	Down-regulation
STE_STE20_PAKA_PAK1_ST	P21333	FLNA	Q13153	PAK1	T1617	P1610T	1610	Missense	distal	-7	no	20.973	21.199	EPSD	ICGC	19.028	Up-regulation
STE_STE20_PAKA_PAK1_ST	P21333	FLNA	Q13153	PAK1	S1961	R1959H	1959	Missense	proximal	-2	no	19.051	13.637	EPSD	ICGC;COSMIC	19.028	Loss
STE_STE20_PAKA_PAK1_ST	P21333	FLNA	Q13153	PAK1	S2260	A2266V	2266	Missense	distal	6	no	19.181	19.502	EPSD	ICGC	19.028	Up-regulation
STE_STE20_PAKA_PAK1_ST	P21333	FLNA	Q13153	PAK1	S2370	A2366S	2366	Missense	distal	-4	no	24.033	23.936	EPSD;PhosphoSitePlus	ICGC;COSMIC	19.028	Down-regulation
STE_STE20_PAKA_PAK1_ST	O43623	SNAI2	Q13153	PAK1	S87	S80F	80	Missense	distal	-7	no	21.018	20.020	EPSD	ICGC;COSMIC	19.028	Down-regulation
STE_STE20_PAKA_PAK1_ST	O43623	SNAI2	Q13153	PAK1	S87	S81L	81	Missense	distal	-6	no	21.018	20.807	EPSD	ICGC	19.028	Down-regulation
STE_STE20_PAKA_PAK1_ST	O43623	SNAI2	Q13153	PAK1	S100	S95T	95	Missense	distal	-5	no	20.384	20.811	EPSD	ICGC;COSMIC	19.028	Up-regulation
STE_STE20_PAKA_PAK1_ST	O43623	SNAI2	Q13153	PAK1	T208	K211M	211	Missense	distal	3	no	17.764	19.322	EPSD	ICGC	19.028	Gain
STE_STE20_PAKA_PAK1_ST	O43623	SNAI2	Q13153	PAK1	S251	M253I	253	Missense	proximal	2	no	20.662	19.786	PhosphoSitePlus	ICGC;COSMIC	19.028	Down-regulation
STE_STE20_PAKA_PAK1_ST	O95863	SNAI1	Q13153	PAK1	S11	D12Y	12	Missense	proximal	1	no	20.424	20.235	EPSD	ICGC;COSMIC	19.028	Down-regulation
STE_STE20_PAKA_PAK1_ST	O95863	SNAI1	Q13153	PAK1	S11	R15L	15	Missense	distal	4	no	20.424	21.822	EPSD	ICGC;COSMIC	19.028	Up-regulation
STE_STE20_PAKA_PAK1_ST	O95863	SNAI1	Q13153	PAK1	S246	R243W	243	Missense	distal	-3	no	20.834	13.274	PhosphoSitePlus	ICGC;COSMIC	19.028	Loss
STE_STE20_PAKA_PAK1_ST	Q15365	PCBP1	Q13153	PAK1	T60	G63V	63	Missense	distal	3	no	20.436	19.149	PhosphoSitePlus;EPSD	ICGC	19.028	Down-regulation
STE_STE20_PAKA_PAK1_ST	Q15365	PCBP1	Q13153	PAK1	T60	N53D	53	Missense	distal	-7	no	20.436	20.840	PhosphoSitePlus;EPSD	ICGC	19.028	Up-regulation
STE_STE20_PAKA_PAK1_ST	Q15365	PCBP1	Q13153	PAK1	T127	Q132H	132	Missense	distal	5	no	19.625	19.640	EPSD;PhosphoSitePlus	ICGC;COSMIC	19.028	Up-regulation
STE_STE20_PAKA_PAK1_ST	Q15365	PCBP1	Q13153	PAK1	T127	E122Q	122	Missense	distal	-5	no	19.625	19.637	EPSD;PhosphoSitePlus	ICGC;COSMIC	19.028	Up-regulation
STE_STE20_PAKA_PAK1_ST	Q15365	PCBP1	Q13153	PAK1	S231	D234N	234	Missense	distal	3	no	20.073	20.350	EPSD	ICGC;COSMIC	19.028	Up-regulation
STE_STE20_PAKA_PAK1_ST	Q15365	PCBP1	Q13153	PAK1	S246	H252R	252	Missense	distal	6	no	19.378	18.934	EPSD	ICGC	19.028	Loss
STE_STE20_PAKA_PAK1_ST	P15056	BRAF	Q13153	PAK1	T167	P162T	162	Missense	distal	-5	no	19.628	19.194	EPSD	ICGC	19.028	Down-regulation
STE_STE20_PAKA_PAK1_ST	P15056	BRAF	Q13153	PAK1	T167	A171S	171	Missense	distal	4	no	19.628	18.652	EPSD	ICGC;COSMIC	19.028	Loss
STE_STE20_PAKA_PAK1_ST	P15056	BRAF	Q13153	PAK1	S323	S316P	316	Missense	distal	-7	no	20.800	20.543	EPSD	ICGC;COSMIC	19.028	Down-regulation
STE_STE20_PAKA_PAK1_ST	P15056	BRAF	Q13153	PAK1	S323	I326V	326	Missense	distal	3	no	20.800	20.719	EPSD	ICGC;COSMIC;GDSC;CCLE	19.028	Down-regulation
STE_STE20_PAKA_PAK1_ST	P15056	BRAF	Q13153	PAK1	S323	P321H	321	Missense	proximal	-2	no	20.800	18.911	EPSD	ICGC	19.028	Loss
STE_STE20_PAKA_PAK1_ST	P15056	BRAF	Q13153	PAK1	S323	P328F	328	Missense	distal	5	no	20.800	20.779	EPSD	ICGC	19.028	Down-regulation
STE_STE20_PAKA_PAK1_ST	P15056	BRAF	Q13153	PAK1	S323	S317P	317	Missense	distal	-6	no	20.800	20.742	EPSD	ICGC	19.028	Down-regulation
STE_STE20_PAKA_PAK1_ST	P15056	BRAF	Q13153	PAK1	S363	Q359K	359	Missense	distal	-4	no	19.461	19.722	EPSD	ICGC	19.028	Up-regulation
STE_STE20_PAKA_PAK1_ST	P15056	BRAF	Q13153	PAK1	S363	S363F	363	Missense	central	0	yes	19.461	0.000	EPSD	ICGC;COSMIC	19.028	Loss
STE_STE20_PAKA_PAK1_ST	P15056	BRAF	Q13153	PAK1	S363	P367L	367	Missense	distal	4	no	19.461	17.903	EPSD	ICGC;COSMIC	19.028	Loss
STE_STE20_PAKA_PAK1_ST	P15056	BRAF	Q13153	PAK1	S363	Q359R	359	Missense	distal	-4	no	19.461	19.929	EPSD	ICGC;COSMIC	19.028	Up-regulation
STE_STE20_PAKA_PAK1_ST	P15056	BRAF	Q13153	PAK1	S364	Q359K	359	Missense	distal	-5	no	22.223	22.271	EPSD	ICGC	19.028	Up-regulation
STE_STE20_PAKA_PAK1_ST	P15056	BRAF	Q13153	PAK1	S364	S363F	363	Missense	proximal	-1	no	22.223	23.020	EPSD	ICGC;COSMIC	19.028	Up-regulation
STE_STE20_PAKA_PAK1_ST	P15056	BRAF	Q13153	PAK1	S364	P367L	367	Missense	distal	3	no	22.223	21.637	EPSD	ICGC;COSMIC	19.028	Down-regulation
STE_STE20_PAKA_PAK1_ST	P15056	BRAF	Q13153	PAK1	S364	Q359R	359	Missense	distal	-5	no	22.223	22.125	EPSD	ICGC;COSMIC	19.028	Down-regulation
STE_STE20_PAKA_PAK1_ST	P15056	BRAF	Q13153	PAK1	S365	N372K	372	Missense	distal	7	no	20.673	20.717	EPSD	ICGC	19.028	Up-regulation
STE_STE20_PAKA_PAK1_ST	P15056	BRAF	Q13153	PAK1	S365	Q359K	359	Missense	distal	-6	no	20.673	19.877	EPSD	ICGC	19.028	Down-regulation
STE_STE20_PAKA_PAK1_ST	P15056	BRAF	Q13153	PAK1	S365	S363F	363	Missense	proximal	-2	no	20.673	23.207	EPSD	ICGC;COSMIC	19.028	Up-regulation
STE_STE20_PAKA_PAK1_ST	P15056	BRAF	Q13153	PAK1	S365	P367L	367	Missense	proximal	2	no	20.673	20.841	EPSD	ICGC;COSMIC	19.028	Up-regulation
STE_STE20_PAKA_PAK1_ST	P15056	BRAF	Q13153	PAK1	S365	Q359R	359	Missense	distal	-6	no	20.673	21.934	EPSD	ICGC;COSMIC	19.028	Up-regulation
STE_STE20_PAKA_PAK1_ST	P15056	BRAF	Q13153	PAK1	S429	S429Y	429	Missense	central	0	yes	21.489	0.000	EPSD	ICGC	19.028	Loss
STE_STE20_PAKA_PAK1_ST	P15056	BRAF	Q13153	PAK1	S429	Q423H	423	Missense	distal	-6	no	21.489	21.892	EPSD	ICGC;COSMIC	19.028	Up-regulation
STE_STE20_PAKA_PAK1_ST	P15056	BRAF	Q13153	PAK1	S429	S428T	428	Missense	proximal	-1	no	21.489	21.968	EPSD	ICGC;COSMIC	19.028	Up-regulation
STE_STE20_PAKA_PAK1_ST	P15056	BRAF	Q13153	PAK1	S430	S429Y	429	Missense	proximal	-1	no	19.943	19.062	EPSD	ICGC	19.028	Down-regulation
STE_STE20_PAKA_PAK1_ST	P15056	BRAF	Q13153	PAK1	S430	Q423H	423	Missense	distal	-7	no	19.943	19.115	EPSD	ICGC;COSMIC	19.028	Down-regulation
STE_STE20_PAKA_PAK1_ST	P15056	BRAF	Q13153	PAK1	S430	S428T	428	Missense	proximal	-2	no	19.943	23.233	EPSD	ICGC;COSMIC	19.028	Up-regulation
STE_STE20_PAKA_PAK1_ST	P15056	BRAF	Q13153	PAK1	T440	R444Q	444	Missense	distal	4	no	19.506	19.795	EPSD	ICGC;COSMIC	19.028	Up-regulation
STE_STE20_PAKA_PAK1_ST	P15056	BRAF	Q13153	PAK1	T440	R444W	444	Missense	distal	4	no	19.506	21.623	EPSD	ICGC;COSMIC	19.028	Up-regulation
STE_STE20_PAKA_PAK1_ST	P15056	BRAF	Q13153	PAK1	T440	T440K	440	Missense	central	0	yes	19.506	0.000	EPSD	ICGC	19.028	Loss
STE_STE20_PAKA_PAK1_ST	P15056	BRAF	Q13153	PAK1	T440	L441I	441	Missense	proximal	1	no	19.506	19.582	EPSD	ICGC;COSMIC	19.028	Up-regulation
STE_STE20_PAKA_PAK1_ST	P15056	BRAF	Q13153	PAK1	T440	S446L	446	Missense	distal	6	no	19.506	19.777	EPSD	ICGC;COSMIC	19.028	Up-regulation
STE_STE20_PAKA_PAK1_ST	P15056	BRAF	Q13153	PAK1	T440	M438I	438	Missense	proximal	-2	no	19.506	17.460	EPSD	ICGC;COSMIC	19.028	Loss
STE_STE20_PAKA_PAK1_ST	P15056	BRAF	Q13153	PAK1	S446	R444Q	444	Missense	proximal	-2	no	31.164	21.957	PhosphoSitePlus	ICGC;COSMIC	19.028	Down-regulation
STE_STE20_PAKA_PAK1_ST	P15056	BRAF	Q13153	PAK1	S446	R444W	444	Missense	proximal	-2	no	31.164	18.226	PhosphoSitePlus	ICGC;COSMIC	19.028	Loss
STE_STE20_PAKA_PAK1_ST	P15056	BRAF	Q13153	PAK1	S446	T440K	440	Missense	distal	-6	no	31.164	30.133	PhosphoSitePlus	ICGC	19.028	Down-regulation
STE_STE20_PAKA_PAK1_ST	P15056	BRAF	Q13153	PAK1	S446	L441I	441	Missense	distal	-5	no	31.164	30.826	PhosphoSitePlus	ICGC;COSMIC	19.028	Down-regulation
STE_STE20_PAKA_PAK1_ST	P15056	BRAF	Q13153	PAK1	S446	E451D	451	Missense	distal	5	no	31.164	31.171	PhosphoSitePlus	ICGC;COSMIC	19.028	Up-regulation
STE_STE20_PAKA_PAK1_ST	P15056	BRAF	Q13153	PAK1	S446	S446L	446	Missense	central	0	yes	31.164	0.000	PhosphoSitePlus	ICGC;COSMIC	19.028	Loss
STE_STE20_PAKA_PAK1_ST	P15056	BRAF	Q13153	PAK1	S447	R444Q	444	Missense	distal	-3	no	23.244	14.519	EPSD	ICGC;COSMIC	19.028	Loss
STE_STE20_PAKA_PAK1_ST	P15056	BRAF	Q13153	PAK1	S447	R444W	444	Missense	distal	-3	no	23.244	15.683	EPSD	ICGC;COSMIC	19.028	Loss
STE_STE20_PAKA_PAK1_ST	P15056	BRAF	Q13153	PAK1	S447	T440K	440	Missense	distal	-7	no	23.244	23.226	EPSD	ICGC	19.028	Down-regulation
STE_STE20_PAKA_PAK1_ST	P15056	BRAF	Q13153	PAK1	S447	L441I	441	Missense	distal	-6	no	23.244	22.389	EPSD	ICGC;COSMIC	19.028	Down-regulation
STE_STE20_PAKA_PAK1_ST	P15056	BRAF	Q13153	PAK1	S447	E451D	451	Missense	distal	4	no	23.244	23.743	EPSD	ICGC;COSMIC	19.028	Up-regulation
STE_STE20_PAKA_PAK1_ST	P15056	BRAF	Q13153	PAK1	S447	S446L	446	Missense	proximal	-1	no	23.244	24.191	EPSD	ICGC;COSMIC	19.028	Up-regulation
STE_STE20_PAKA_PAK1_ST	P15056	BRAF	Q13153	PAK1	S465	V471F	471	Missense	distal	6	no	21.053	21.092	EPSD	ICGC;COSMIC	19.028	Up-regulation
STE_STE20_PAKA_PAK1_ST	P15056	BRAF	Q13153	PAK1	S465	Q461K	461	Missense	distal	-4	no	21.053	21.314	EPSD	ICGC	19.028	Up-regulation
STE_STE20_PAKA_PAK1_ST	P15056	BRAF	Q13153	PAK1	S465	G466R	466	Missense	proximal	1	no	21.053	21.534	EPSD	ICGC;COSMIC	19.028	Up-regulation
STE_STE20_PAKA_PAK1_ST	P15056	BRAF	Q13153	PAK1	S465	S465Y	465	Missense	central	0	yes	21.053	0.000	EPSD	ICGC	19.028	Loss
STE_STE20_PAKA_PAK1_ST	P15056	BRAF	Q13153	PAK1	S465	R462K	462	Missense	distal	-3	no	21.053	19.866	EPSD	ICGC;COSMIC	19.028	Down-regulation
STE_STE20_PAKA_PAK1_ST	P15056	BRAF	Q13153	PAK1	S602	V600R	600	Missense	proximal	-2	no	16.111	21.670	EPSD	ICGC;COSMIC	19.028	Gain
STE_STE20_PAKA_PAK1_ST	Q96T58	SPEN	Q13153	PAK1	S43	G42V	42	Missense	proximal	-1	no	28.417	29.485	EPSD	ICGC	19.028	Up-regulation
STE_STE20_PAKA_PAK1_ST	Q96T58	SPEN	Q13153	PAK1	S43	S43P	43	Missense	central	0	yes	28.417	0.000	EPSD	ICGC;COSMIC	19.028	Loss
STE_STE20_PAKA_PAK1_ST	Q96T58	SPEN	Q13153	PAK1	S43	R41M	41	Missense	proximal	-2	no	28.417	24.179	EPSD	ICGC;COSMIC	19.028	Down-regulation
STE_STE20_PAKA_PAK1_ST	Q96T58	SPEN	Q13153	PAK1	S147	R154W	154	Missense	distal	7	no	22.087	22.268	EPSD	ICGC;COSMIC	19.028	Up-regulation
STE_STE20_PAKA_PAK1_ST	Q96T58	SPEN	Q13153	PAK1	T177	R174Q	174	Missense	distal	-3	no	20.661	11.937	EPSD	ICGC;COSMIC	19.028	Loss
STE_STE20_PAKA_PAK1_ST	Q96T58	SPEN	Q13153	PAK1	T177	R176L	176	Missense	proximal	-1	no	20.661	20.529	EPSD	ICGC;COSMIC	19.028	Down-regulation
STE_STE20_PAKA_PAK1_ST	Q96T58	SPEN	Q13153	PAK1	S268	T266R	266	Missense	proximal	-2	no	18.734	23.597	EPSD	ICGC;COSMIC	19.028	Gain
STE_STE20_PAKA_PAK1_ST	Q96T58	SPEN	Q13153	PAK1	S270	R275K	275	Missense	distal	5	no	22.190	22.198	EPSD	ICGC;COSMIC	19.028	Up-regulation
STE_STE20_PAKA_PAK1_ST	Q96T58	SPEN	Q13153	PAK1	S270	G273S	273	Missense	distal	3	no	22.190	19.445	EPSD	ICGC;COSMIC	19.028	Down-regulation
STE_STE20_PAKA_PAK1_ST	Q96T58	SPEN	Q13153	PAK1	S270	T266R	266	Missense	distal	-4	no	22.190	22.143	EPSD	ICGC;COSMIC	19.028	Down-regulation
STE_STE20_PAKA_PAK1_ST	Q96T58	SPEN	Q13153	PAK1	S270	G271C	271	Missense	proximal	1	no	22.190	22.227	EPSD	ICGC;COSMIC	19.028	Up-regulation
STE_STE20_PAKA_PAK1_ST	Q96T58	SPEN	Q13153	PAK1	S270	G273V	273	Missense	distal	3	no	22.190	20.902	EPSD	ICGC	19.028	Down-regulation
STE_STE20_PAKA_PAK1_ST	Q96T58	SPEN	Q13153	PAK1	S278	R275K	275	Missense	distal	-3	no	20.454	19.267	EPSD	ICGC;COSMIC	19.028	Down-regulation
STE_STE20_PAKA_PAK1_ST	Q96T58	SPEN	Q13153	PAK1	S278	G273S	273	Missense	distal	-5	no	20.454	19.539	EPSD	ICGC;COSMIC	19.028	Down-regulation
STE_STE20_PAKA_PAK1_ST	Q96T58	SPEN	Q13153	PAK1	S278	G271C	271	Missense	distal	-7	no	20.454	19.694	EPSD	ICGC;COSMIC	19.028	Down-regulation
STE_STE20_PAKA_PAK1_ST	Q96T58	SPEN	Q13153	PAK1	S278	G273V	273	Missense	distal	-5	no	20.454	20.042	EPSD	ICGC	19.028	Down-regulation
STE_STE20_PAKA_PAK1_ST	Q96T58	SPEN	Q13153	PAK1	S320	P318R	318	Missense	proximal	-2	no	18.051	21.576	EPSD	ICGC;COSMIC	19.028	Gain
STE_STE20_PAKA_PAK1_ST	Q96T58	SPEN	Q13153	PAK1	S334	Q340L	340	Missense	distal	6	no	27.419	27.804	EPSD	ICGC;COSMIC	19.028	Up-regulation
STE_STE20_PAKA_PAK1_ST	Q96T58	SPEN	Q13153	PAK1	S334	E330D	330	Missense	distal	-4	no	27.419	27.297	EPSD	ICGC;COSMIC	19.028	Down-regulation
STE_STE20_PAKA_PAK1_ST	Q96T58	SPEN	Q13153	PAK1	S334	I337M	337	Missense	distal	3	no	27.419	27.771	EPSD	ICGC;COSMIC	19.028	Up-regulation
STE_STE20_PAKA_PAK1_ST	Q96T58	SPEN	Q13153	PAK1	S623	R620Q	620	Missense	distal	-3	no	30.999	22.274	EPSD	ICGC;COSMIC	19.028	Down-regulation
STE_STE20_PAKA_PAK1_ST	Q96T58	SPEN	Q13153	PAK1	S727	Q726E	726	Missense	proximal	-1	no	19.497	18.201	EPSD	ICGC;COSMIC	19.028	Loss
STE_STE20_PAKA_PAK1_ST	Q96T58	SPEN	Q13153	PAK1	S736	Q735H	735	Missense	proximal	-1	no	25.750	24.661	EPSD	ICGC;COSMIC	19.028	Down-regulation
STE_STE20_PAKA_PAK1_ST	Q96T58	SPEN	Q13153	PAK1	S1062	A1061T	1061	Missense	proximal	-1	no	17.035	20.065	EPSD	ICGC;COSMIC	19.028	Gain
STE_STE20_PAKA_PAK1_ST	Q96T58	SPEN	Q13153	PAK1	S1222	P1223T	1223	Missense	proximal	1	no	18.988	19.514	EPSD	ICGC;COSMIC	19.028	Gain
STE_STE20_PAKA_PAK1_ST	Q96T58	SPEN	Q13153	PAK1	S1225	S1222F	1222	Missense	distal	-3	no	15.948	19.460	EPSD	ICGC;COSMIC	19.028	Gain
STE_STE20_PAKA_PAK1_ST	Q96T58	SPEN	Q13153	PAK1	S1268	S1263I	1263	Missense	distal	-5	no	18.755	19.177	EPSD	ICGC;COSMIC	19.028	Gain
STE_STE20_PAKA_PAK1_ST	Q96T58	SPEN	Q13153	PAK1	S1364	S1369F	1369	Missense	distal	5	no	23.112	23.120	EPSD	ICGC;COSMIC	19.028	Up-regulation
STE_STE20_PAKA_PAK1_ST	Q96T58	SPEN	Q13153	PAK1	S1364	R1362I	1362	Missense	proximal	-2	no	23.112	16.828	EPSD	ICGC;COSMIC	19.028	Loss
STE_STE20_PAKA_PAK1_ST	Q96T58	SPEN	Q13153	PAK1	S1369	S1369F	1369	Missense	central	0	yes	22.353	0.000	EPSD	ICGC;COSMIC	19.028	Loss
STE_STE20_PAKA_PAK1_ST	Q96T58	SPEN	Q13153	PAK1	S1369	P1375A	1375	Missense	distal	6	no	22.353	22.121	EPSD	ICGC;COSMIC	19.028	Down-regulation
STE_STE20_PAKA_PAK1_ST	Q96T58	SPEN	Q13153	PAK1	S1369	R1362I	1362	Missense	distal	-7	no	22.353	20.956	EPSD	ICGC;COSMIC	19.028	Down-regulation
STE_STE20_PAKA_PAK1_ST	Q96T58	SPEN	Q13153	PAK1	S1396	R1403L	1403	Missense	distal	7	no	23.744	23.892	EPSD	ICGC	19.028	Up-regulation
STE_STE20_PAKA_PAK1_ST	Q96T58	SPEN	Q13153	PAK1	S1396	H1391N	1391	Missense	distal	-5	no	23.744	23.963	EPSD	ICGC;COSMIC	19.028	Up-regulation
STE_STE20_PAKA_PAK1_ST	Q96T58	SPEN	Q13153	PAK1	S1402	R1403L	1403	Missense	proximal	1	no	20.231	19.999	EPSD	ICGC	19.028	Down-regulation
STE_STE20_PAKA_PAK1_ST	Q96T58	SPEN	Q13153	PAK1	S1402	L1407F	1407	Missense	distal	5	no	20.231	20.224	EPSD	ICGC;COSMIC	19.028	Down-regulation
STE_STE20_PAKA_PAK1_ST	Q96T58	SPEN	Q13153	PAK1	S1453	A1451V	1451	Missense	proximal	-2	no	19.527	21.787	EPSD	ICGC;COSMIC	19.028	Up-regulation
STE_STE20_PAKA_PAK1_ST	Q96T58	SPEN	Q13153	PAK1	S1453	E1449G	1449	Missense	distal	-4	no	19.527	18.926	EPSD	ICGC;COSMIC	19.028	Loss
STE_STE20_PAKA_PAK1_ST	Q96T58	SPEN	Q13153	PAK1	S1455	A1451V	1451	Missense	distal	-4	no	19.989	19.801	EPSD	ICGC;COSMIC	19.028	Down-regulation
STE_STE20_PAKA_PAK1_ST	Q96T58	SPEN	Q13153	PAK1	S1455	E1449G	1449	Missense	distal	-6	no	19.989	18.594	EPSD	ICGC;COSMIC	19.028	Loss
STE_STE20_PAKA_PAK1_ST	Q96T58	SPEN	Q13153	PAK1	S1485	D1479H	1479	Missense	distal	-6	no	23.714	24.655	EPSD	ICGC;COSMIC	19.028	Up-regulation
STE_STE20_PAKA_PAK1_ST	Q96T58	SPEN	Q13153	PAK1	S1485	V1483A	1483	Missense	proximal	-2	no	23.714	21.454	EPSD	ICGC;COSMIC	19.028	Down-regulation
STE_STE20_PAKA_PAK1_ST	Q96T58	SPEN	Q13153	PAK1	S1485	A1486T	1486	Missense	proximal	1	no	23.714	24.209	EPSD	ICGC;COSMIC	19.028	Up-regulation
STE_STE20_PAKA_PAK1_ST	Q96T58	SPEN	Q13153	PAK1	S1641	G1638R	1638	Missense	distal	-3	no	13.792	21.669	EPSD	ICGC;COSMIC	19.028	Gain
STE_STE20_PAKA_PAK1_ST	Q96T58	SPEN	Q13153	PAK1	S1797	A1791V	1791	Missense	distal	-6	no	19.532	18.745	EPSD	ICGC	19.028	Loss
STE_STE20_PAKA_PAK1_ST	Q96T58	SPEN	Q13153	PAK1	S1797	A1794S	1794	Missense	distal	-3	no	19.532	17.484	EPSD	ICGC	19.028	Loss
STE_STE20_PAKA_PAK1_ST	Q96T58	SPEN	Q13153	PAK1	S1797	P1800L	1800	Missense	distal	3	no	19.532	18.945	EPSD	ICGC	19.028	Loss
STE_STE20_PAKA_PAK1_ST	Q96T58	SPEN	Q13153	PAK1	S1802	P1800L	1800	Missense	proximal	-2	no	19.738	14.698	EPSD	ICGC	19.028	Loss
STE_STE20_PAKA_PAK1_ST	Q96T58	SPEN	Q13153	PAK1	S1855	S1857Y	1857	Missense	proximal	2	no	18.792	21.043	EPSD	ICGC;COSMIC	19.028	Gain
STE_STE20_PAKA_PAK1_ST	Q96T58	SPEN	Q13153	PAK1	S1986	R1982W	1982	Missense	distal	-4	no	19.175	18.190	EPSD	ICGC;COSMIC;GDSC;CCLE	19.028	Loss
STE_STE20_PAKA_PAK1_ST	Q96T58	SPEN	Q13153	PAK1	S1986	R1982Q	1982	Missense	distal	-4	no	19.175	18.706	EPSD	ICGC	19.028	Loss
STE_STE20_PAKA_PAK1_ST	Q96T58	SPEN	Q13153	PAK1	S1986	G1993C	1993	Missense	distal	7	no	19.175	19.246	EPSD	ICGC	19.028	Up-regulation
STE_STE20_PAKA_PAK1_ST	Q96T58	SPEN	Q13153	PAK1	S1986	Q1987K	1987	Missense	proximal	1	no	19.175	19.154	EPSD	ICGC;COSMIC	19.028	Down-regulation
STE_STE20_PAKA_PAK1_ST	Q96T58	SPEN	Q13153	PAK1	S2452	D2457N	2457	Missense	distal	5	no	23.633	23.646	EPSD	ICGC;COSMIC	19.028	Up-regulation
STE_STE20_PAKA_PAK1_ST	Q96T58	SPEN	Q13153	PAK1	S2481	P2482R	2482	Missense	proximal	1	no	20.164	20.683	EPSD	ICGC	19.028	Up-regulation
STE_STE20_PAKA_PAK1_ST	Q96T58	SPEN	Q13153	PAK1	S2481	P2483L	2483	Missense	proximal	2	no	20.164	20.332	EPSD	ICGC	19.028	Up-regulation
STE_STE20_PAKA_PAK1_ST	Q96T58	SPEN	Q13153	PAK1	T2685	A2687S	2687	Missense	proximal	2	no	19.856	18.952	EPSD	ICGC	19.028	Loss
STE_STE20_PAKA_PAK1_ST	Q96T58	SPEN	Q13153	PAK1	T2685	G2688R	2688	Missense	distal	3	no	19.856	17.270	EPSD	ICGC;COSMIC	19.028	Loss
STE_STE20_PAKA_PAK1_ST	Q96T58	SPEN	Q13153	PAK1	S2778	Q2775H	2775	Missense	distal	-3	no	16.928	19.581	EPSD	ICGC;COSMIC	19.028	Gain
STE_STE20_PAKA_PAK1_ST	Q96T58	SPEN	Q13153	PAK1	S2860	Q2855K	2855	Missense	distal	-5	no	19.348	19.396	EPSD	ICGC;COSMIC	19.028	Up-regulation
STE_STE20_PAKA_PAK1_ST	Q96T58	SPEN	Q13153	PAK1	S2860	S2860Y	2860	Missense	central	0	yes	19.348	0.000	EPSD	ICGC;COSMIC	19.028	Loss
STE_STE20_PAKA_PAK1_ST	Q96T58	SPEN	Q13153	PAK1	S2884	V2887L	2887	Missense	distal	3	no	18.979	19.316	EPSD	ICGC	19.028	Gain
STE_STE20_PAKA_PAK1_ST	Q96T58	SPEN	Q13153	PAK1	S3014	R3011L	3011	Missense	distal	-3	no	22.994	16.503	EPSD	ICGC;COSMIC	19.028	Loss
STE_STE20_PAKA_PAK1_ST	Q96T58	SPEN	Q13153	PAK1	S3029	P3031A	3031	Missense	proximal	2	no	22.126	22.385	EPSD	ICGC	19.028	Up-regulation
STE_STE20_PAKA_PAK1_ST	Q96T58	SPEN	Q13153	PAK1	S3035	P3031A	3031	Missense	distal	-4	no	18.975	19.124	EPSD	ICGC	19.028	Gain
STE_STE20_PAKA_PAK1_ST	Q96T58	SPEN	Q13153	PAK1	T3139	A3133T	3133	Missense	distal	-6	no	20.528	20.454	EPSD	ICGC	19.028	Down-regulation
STE_STE20_PAKA_PAK1_ST	Q96T58	SPEN	Q13153	PAK1	S3430	S3430F	3430	Missense	central	0	yes	21.419	0.000	EPSD	ICGC	19.028	Loss
STE_STE20_PAKA_PAK1_ST	Q96T58	SPEN	Q13153	PAK1	S3430	P3428Q	3428	Missense	proximal	-2	no	21.419	15.737	EPSD	ICGC;COSMIC	19.028	Loss
STE_STE20_PAKA_PAK1_ST	Q96T58	SPEN	Q13153	PAK1	T3568	T3568M	3568	Missense	central	0	yes	24.389	0.000	PhosphoSitePlus;EPSD	ICGC;COSMIC	19.028	Loss
STE_STE20_PAKA_PAK1_ST	Q96T58	SPEN	Q13153	PAK1	T3568	Y3573C	3573	Missense	distal	5	no	24.389	24.380	PhosphoSitePlus;EPSD	ICGC;COSMIC	19.028	Down-regulation
STE_STE20_PAKA_PAK1_ST	Q96T58	SPEN	Q13153	PAK1	T3568	M3567I	3567	Missense	proximal	-1	no	24.389	25.854	PhosphoSitePlus;EPSD	ICGC;COSMIC	19.028	Up-regulation
STE_STE20_PAKA_PAK1_ST	O14965	AURKA	Q13153	PAK1	S67	P70L	70	Missense	distal	3	no	19.585	18.999	EPSD	ICGC;COSMIC;CCLE	19.028	Loss
STE_STE20_PAKA_PAK1_ST	O14965	AURKA	Q13153	PAK1	T287	C290Y	290	Missense	distal	3	no	19.536	22.160	EPSD	ICGC	19.028	Up-regulation
STE_STE20_PAKA_PAK1_ST	O14965	AURKA	Q13153	PAK1	T287	H280N	280	Missense	distal	-7	no	19.536	19.651	EPSD	ICGC	19.028	Up-regulation
STE_STE20_PAKA_PAK1_ST	O14965	AURKA	Q13153	PAK1	T287	D294E	294	Missense	distal	7	no	19.536	19.521	EPSD	ICGC;COSMIC	19.028	Down-regulation
STE_STE20_PAKA_PAK1_ST	O14965	AURKA	Q13153	PAK1	T288	C290Y	290	Missense	proximal	2	no	27.239	28.858	EPSD;PhosphoSitePlus	ICGC	19.028	Up-regulation
STE_STE20_PAKA_PAK1_ST	O14965	AURKA	Q13153	PAK1	T288	D294E	294	Missense	distal	6	no	27.239	27.094	EPSD;PhosphoSitePlus	ICGC;COSMIC	19.028	Down-regulation
STE_STE20_PAKA_PAK1_ST	O14965	AURKA	Q13153	PAK1	S342	I341V	341	Missense	proximal	-1	no	30.054	28.510	PhosphoSitePlus;EPSD	ICGC;COSMIC	19.028	Down-regulation
STE_STE20_PAKA_PAK1_ST	O14965	AURKA	Q13153	PAK1	S342	R340I	340	Missense	proximal	-2	no	30.054	23.770	PhosphoSitePlus;EPSD	ICGC	19.028	Down-regulation
STE_STE20_PAKA_PAK1_ST	O14965	AURKA	Q13153	PAK1	S342	R343W	343	Missense	proximal	1	no	30.054	29.460	PhosphoSitePlus;EPSD	ICGC;COSMIC	19.028	Down-regulation
STE_STE20_PAKA_PAK1_ST	O14965	AURKA	Q13153	PAK1	S342	Q335K	335	Missense	distal	-7	no	30.054	29.959	PhosphoSitePlus;EPSD	ICGC;COSMIC	19.028	Down-regulation
STE_STE20_PAKA_PAK1_ST	P16949	STMN1	Q13153	PAK1	S28	S31P	31	Missense	distal	3	no	17.392	19.772	EPSD	ICGC;COSMIC	19.028	Gain
STE_STE20_PAKA_PAK1_ST	P16949	STMN1	Q13153	PAK1	S38	S31P	31	Missense	distal	-7	no	19.215	18.958	PhosphoSitePlus;EPSD	ICGC;COSMIC	19.028	Loss
STE_STE20_PAKA_PAK1_ST	P16949	STMN1	Q13153	PAK1	S63	S63F	63	Missense	central	0	yes	30.985	0.000	EPSD	ICGC;COSMIC	19.028	Loss
STE_STE20_PAKA_PAK1_ST	P35240	NF2	Q13153	PAK1	S255	W258C	258	Missense	distal	3	no	21.639	20.232	EPSD	ICGC	19.028	Down-regulation
STE_STE20_PAKA_PAK1_ST	P35240	NF2	Q13153	PAK1	S265	W258C	258	Missense	distal	-7	no	19.418	19.034	EPSD	ICGC	19.028	Down-regulation
STE_STE20_PAKA_PAK1_ST	P35240	NF2	Q13153	PAK1	S518	E520K	520	Missense	proximal	2	no	27.300	27.603	PhosphoSitePlus	ICGC;COSMIC	19.028	Up-regulation
STE_STE20_PAKA_PAK1_ST	P35240	NF2	Q13153	PAK1	S518	R516W	516	Missense	proximal	-2	no	27.300	14.362	PhosphoSitePlus	ICGC;COSMIC	19.028	Loss
STE_STE20_PAKA_PAK1_ST	P35240	NF2	Q13153	PAK1	S518	R516L	516	Missense	proximal	-2	no	27.300	18.736	PhosphoSitePlus	ICGC	19.028	Loss
STE_STE20_PAKA_PAK1_ST	Q9UQ80	PA2G4	Q13153	PAK1	S252	I246V	246	Missense	distal	-6	no	18.045	19.381	EPSD	ICGC;COSMIC	19.028	Gain
STE_STE20_PAKA_PAK1_ST	Q9UQ80	PA2G4	Q13153	PAK1	T261	F265L	265	Missense	distal	4	no	23.041	22.370	PhosphoSitePlus	ICGC;COSMIC	19.028	Down-regulation
STE_STE20_PAKA_PAK1_ST	Q9UQ80	PA2G4	Q13153	PAK1	T261	E268G	268	Missense	distal	7	no	23.041	23.141	PhosphoSitePlus	ICGC;COSMIC	19.028	Up-regulation
STE_STE20_PAKA_PAK1_ST	Q9UQ80	PA2G4	Q13153	PAK1	T261	E268K	268	Missense	distal	7	no	23.041	23.096	PhosphoSitePlus	ICGC;COSMIC	19.028	Up-regulation
STE_STE20_PAKA_PAK1_ST	Q9UQ80	PA2G4	Q13153	PAK1	T334	R332W	332	Missense	proximal	-2	no	22.274	9.336	EPSD	ICGC;COSMIC	19.028	Loss
STE_STE20_PAKA_PAK1_ST	Q9UQ80	PA2G4	Q13153	PAK1	T334	P337T	337	Missense	distal	3	no	22.274	20.361	EPSD	ICGC;COSMIC	19.028	Down-regulation
STE_STE20_PAKA_PAK1_ST	Q9UQ80	PA2G4	Q13153	PAK1	S335	R332W	332	Missense	distal	-3	no	20.462	12.901	EPSD	ICGC;COSMIC	19.028	Loss
STE_STE20_PAKA_PAK1_ST	Q9UQ80	PA2G4	Q13153	PAK1	S335	P337T	337	Missense	proximal	2	no	20.462	19.078	EPSD	ICGC;COSMIC	19.028	Down-regulation
STE_STE20_PAKA_PAK1_ST	Q13761	RUNX3	Q13153	PAK1	S71	E65Q	65	Missense	distal	-6	no	22.360	22.000	EPSD	ICGC;COSMIC	19.028	Down-regulation
STE_STE20_PAKA_PAK1_ST	P53667	LIMK1	Q13153	PAK1	S298	R295Q	295	Missense	distal	-3	no	19.466	10.742	EPSD	ICGC;COSMIC	19.028	Loss
STE_STE20_PAKA_PAK1_ST	P53667	LIMK1	Q13153	PAK1	S323	R325C	325	Missense	proximal	2	no	19.027	20.045	EPSD	ICGC;COSMIC	19.028	Gain
STE_STE20_PAKA_PAK1_ST	P53667	LIMK1	Q13153	PAK1	S534	V538I	538	Missense	distal	4	no	20.848	20.746	EPSD	ICGC;COSMIC	19.028	Down-regulation
STE_STE20_PAKA_PAK1_ST	Q70Z35	PREX2	Q13153	PAK1	S901	S907T	907	Missense	distal	6	no	19.357	19.082	EPSD	ICGC;COSMIC	19.028	Down-regulation
STE_STE20_PAKA_PAK1_ST	Q70Z35	PREX2	Q13153	PAK1	S907	R913M	913	Missense	distal	6	no	23.618	24.465	EPSD	ICGC;COSMIC	19.028	Up-regulation
STE_STE20_PAKA_PAK1_ST	Q70Z35	PREX2	Q13153	PAK1	T952	S953Y	953	Missense	proximal	1	no	19.141	19.052	EPSD	ICGC;COSMIC	19.028	Down-regulation
STE_STE20_PAKA_PAK1_ST	Q70Z35	PREX2	Q13153	PAK1	T952	A957T	957	Missense	distal	5	no	19.141	19.128	EPSD	ICGC;COSMIC;GDSC;CCLE	19.028	Down-regulation
STE_STE20_PAKA_PAK1_ST	Q70Z35	PREX2	Q13153	PAK1	T952	T952N	952	Missense	central	0	yes	19.141	0.000	EPSD	ICGC;COSMIC	19.028	Loss
STE_STE20_PAKA_PAK1_ST	Q70Z35	PREX2	Q13153	PAK1	S1057	I1054K	1054	Missense	distal	-3	no	5.083	19.363	EPSD	ICGC;COSMIC	19.028	Gain
STE_STE20_PAKA_PAK1_ST	Q70Z35	PREX2	Q13153	PAK1	S1065	D1072E	1072	Missense	distal	7	no	31.089	31.074	EPSD	ICGC;COSMIC	19.028	Down-regulation
STE_STE20_PAKA_PAK1_ST	Q70Z35	PREX2	Q13153	PAK1	S1065	G1067D	1067	Missense	proximal	2	no	31.089	30.277	EPSD	ICGC	19.028	Down-regulation
STE_STE20_PAKA_PAK1_ST	Q70Z35	PREX2	Q13153	PAK1	S1107	I1102T	1102	Missense	distal	-5	no	22.274	22.279	PhosphoSitePlus	ICGC;COSMIC	19.028	Up-regulation
STE_STE20_PAKA_PAK1_ST	Q70Z35	PREX2	Q13153	PAK1	S1107	S1103I	1103	Missense	distal	-4	no	22.274	22.511	PhosphoSitePlus	ICGC	19.028	Up-regulation
STE_STE20_PAKA_PAK1_ST	Q70Z35	PREX2	Q13153	PAK1	S1107	S1103G	1103	Missense	distal	-4	no	22.274	21.854	PhosphoSitePlus	ICGC;COSMIC	19.028	Down-regulation
STE_STE20_PAKA_PAK1_ST	Q02750	MAP2K1	Q13153	PAK1	T55	F53C	53	Missense	proximal	-2	no	19.774	12.671	EPSD	ICGC;COSMIC	19.028	Loss
STE_STE20_PAKA_PAK1_ST	Q02750	MAP2K1	Q13153	PAK1	T292	P288H	288	Missense	distal	-4	no	27.677	27.762	EPSD	ICGC;COSMIC	19.028	Up-regulation
STE_STE20_PAKA_PAK1_ST	Q02750	MAP2K1	Q13153	PAK1	T292	G294W	294	Missense	proximal	2	no	27.677	27.981	EPSD	ICGC;COSMIC	19.028	Up-regulation
STE_STE20_PAKA_PAK1_ST	Q02750	MAP2K1	Q13153	PAK1	T292	P296H	296	Missense	distal	4	no	27.677	25.587	EPSD	ICGC;COSMIC	19.028	Down-regulation
STE_STE20_PAKA_PAK1_ST	Q02750	MAP2K1	Q13153	PAK1	S298	G294W	294	Missense	distal	-4	no	33.212	33.114	PhosphoSitePlus	ICGC;COSMIC	19.028	Down-regulation
STE_STE20_PAKA_PAK1_ST	Q02750	MAP2K1	Q13153	PAK1	S298	P296H	296	Missense	proximal	-2	no	33.212	31.323	PhosphoSitePlus	ICGC;COSMIC	19.028	Down-regulation
STE_STE20_PAKA_PAK1_ST	Q02750	MAP2K1	Q13153	PAK1	S299	G294W	294	Missense	distal	-5	no	18.971	19.155	EPSD	ICGC;COSMIC	19.028	Gain
STE_STE20_PAKA_PAK1_ST	Q8IYU2	HACE1	Q13153	PAK1	S14	V21M	21	Missense	distal	7	no	20.181	20.312	EPSD	ICGC;COSMIC	19.028	Up-regulation
STE_STE20_PAKA_PAK1_ST	Q8IYU2	HACE1	Q13153	PAK1	T20	V21M	21	Missense	proximal	1	no	26.446	26.531	EPSD	ICGC;COSMIC	19.028	Up-regulation
STE_STE20_PAKA_PAK1_ST	Q8IYU2	HACE1	Q13153	PAK1	S385	T389A	389	Missense	distal	4	no	27.095	28.438	PhosphoSitePlus	ICGC;COSMIC	19.028	Up-regulation
STE_STE20_PAKA_PAK1_ST	Q8IYU2	HACE1	Q13153	PAK1	S385	T389S	389	Missense	distal	4	no	27.095	27.462	PhosphoSitePlus	ICGC;COSMIC	19.028	Up-regulation
STE_STE20_PAKA_PAK1_ST	Q8IYU2	HACE1	Q13153	PAK1	T386	S385T	385	Missense	proximal	-1	no	19.413	19.892	EPSD	ICGC;COSMIC	19.028	Up-regulation
STE_STE20_PAKA_PAK1_ST	Q8IYU2	HACE1	Q13153	PAK1	T386	T389A	389	Missense	distal	3	no	19.413	20.659	EPSD	ICGC;COSMIC	19.028	Up-regulation
STE_STE20_PAKA_PAK1_ST	Q8IYU2	HACE1	Q13153	PAK1	T386	T389S	389	Missense	distal	3	no	19.413	18.946	EPSD	ICGC;COSMIC	19.028	Loss
STE_STE20_PAKA_PAK1_ST	P03372	ESR1	Q13153	PAK1	S154	S154L	154	Missense	central	0	yes	26.206	0.000	EPSD	ICGC	19.028	Loss
STE_STE20_PAKA_PAK1_ST	P03372	ESR1	Q13153	PAK1	S154	R158H	158	Missense	distal	4	no	26.206	27.070	EPSD	ICGC;COSMIC;CCLE	19.028	Up-regulation
STE_STE20_PAKA_PAK1_ST	P03372	ESR1	Q13153	PAK1	S154	N153K	153	Missense	proximal	-1	no	26.206	29.559	EPSD	ICGC	19.028	Up-regulation
STE_STE20_PAKA_PAK1_ST	P03372	ESR1	Q13153	PAK1	S154	P147L	147	Missense	distal	-7	no	26.206	25.760	EPSD	ICGC;COSMIC	19.028	Down-regulation
STE_STE20_PAKA_PAK1_ST	P03372	ESR1	Q13153	PAK1	S212	C205Y	205	Missense	distal	-7	no	20.050	20.238	EPSD	ICGC;COSMIC	19.028	Up-regulation
STE_STE20_PAKA_PAK1_ST	P03372	ESR1	Q13153	PAK1	S236	Q238R	238	Missense	proximal	2	no	25.537	25.201	EPSD	ICGC	19.028	Down-regulation
STE_STE20_PAKA_PAK1_ST	P03372	ESR1	Q13153	PAK1	S236	L242I	242	Missense	distal	6	no	25.537	25.481	EPSD	ICGC	19.028	Down-regulation
STE_STE20_PAKA_PAK1_ST	P03372	ESR1	Q13153	PAK1	S236	R233M	233	Missense	distal	-3	no	25.537	17.968	EPSD	ICGC;COSMIC	19.028	Loss
STE_STE20_PAKA_PAK1_ST	P03372	ESR1	Q13153	PAK1	S305	K302T	302	Missense	distal	-3	no	23.459	18.388	PhosphoSitePlus	ICGC;COSMIC	19.028	Loss
STE_STE20_PAKA_PAK1_ST	P03372	ESR1	Q13153	PAK1	S305	R300L	300	Missense	distal	-5	no	23.459	24.249	PhosphoSitePlus	ICGC;COSMIC	19.028	Up-regulation
STE_STE20_PAKA_PAK1_ST	P03372	ESR1	Q13153	PAK1	S305	R300S	300	Missense	distal	-5	no	23.459	23.488	PhosphoSitePlus	ICGC;COSMIC	19.028	Up-regulation
STE_STE20_PAKA_PAK1_ST	P03372	ESR1	Q13153	PAK1	S305	R300H	300	Missense	distal	-5	no	23.459	23.905	PhosphoSitePlus	ICGC;COSMIC	19.028	Up-regulation
STE_STE20_PAKA_PAK1_ST	P03372	ESR1	Q13153	PAK1	S554	R555L	555	Missense	proximal	1	no	22.051	21.819	EPSD	ICGC	19.028	Down-regulation
STE_STE20_PAKA_PAK1_ST	Q15746	MYLK	Q13153	PAK1	T118	Q116K	116	Missense	proximal	-2	no	14.821	19.991	EPSD	ICGC	19.028	Gain
STE_STE20_PAKA_PAK1_ST	Q15746	MYLK	Q13153	PAK1	S145	P147S	147	Missense	proximal	2	no	22.803	22.158	EPSD	ICGC	19.028	Down-regulation
STE_STE20_PAKA_PAK1_ST	Q15746	MYLK	Q13153	PAK1	S145	R152S	152	Missense	distal	7	no	22.803	22.895	EPSD	ICGC	19.028	Up-regulation
STE_STE20_PAKA_PAK1_ST	Q15746	MYLK	Q13153	PAK1	S343	T341S	341	Missense	proximal	-2	no	20.279	16.989	EPSD	ICGC;COSMIC	19.028	Loss
STE_STE20_PAKA_PAK1_ST	Q15746	MYLK	Q13153	PAK1	S365	P359Q	359	Missense	distal	-6	no	19.213	20.019	EPSD	ICGC	19.028	Up-regulation
STE_STE20_PAKA_PAK1_ST	Q15746	MYLK	Q13153	PAK1	S365	A358E	358	Missense	distal	-7	no	19.213	20.067	EPSD	ICGC	19.028	Up-regulation
STE_STE20_PAKA_PAK1_ST	Q15746	MYLK	Q13153	PAK1	S422	K426N	426	Missense	distal	4	no	21.528	21.501	EPSD	ICGC;COSMIC	19.028	Down-regulation
STE_STE20_PAKA_PAK1_ST	Q15746	MYLK	Q13153	PAK1	S422	Q423K	423	Missense	proximal	1	no	21.528	21.507	EPSD	ICGC	19.028	Down-regulation
STE_STE20_PAKA_PAK1_ST	Q15746	MYLK	Q13153	PAK1	S609	V615M	615	Missense	distal	6	no	25.023	25.268	EPSD	ICGC	19.028	Up-regulation
STE_STE20_PAKA_PAK1_ST	Q15746	MYLK	Q13153	PAK1	S609	A616T	616	Missense	distal	7	no	25.023	24.728	EPSD	ICGC;COSMIC	19.028	Down-regulation
STE_STE20_PAKA_PAK1_ST	Q15746	MYLK	Q13153	PAK1	S848	R845C	845	Missense	distal	-3	no	23.409	3.453	EPSD	ICGC;COSMIC	19.028	Loss
STE_STE20_PAKA_PAK1_ST	Q15746	MYLK	Q13153	PAK1	S848	G841C	841	Missense	distal	-7	no	23.409	22.649	EPSD	ICGC;COSMIC	19.028	Down-regulation
STE_STE20_PAKA_PAK1_ST	Q15746	MYLK	Q13153	PAK1	S947	E942Q	942	Missense	distal	-5	no	19.631	19.643	EPSD	ICGC;COSMIC	19.028	Up-regulation
STE_STE20_PAKA_PAK1_ST	Q15746	MYLK	Q13153	PAK1	S947	R954S	954	Missense	distal	7	no	19.631	19.723	EPSD	ICGC	19.028	Up-regulation
STE_STE20_PAKA_PAK1_ST	Q15746	MYLK	Q13153	PAK1	S947	E941K	941	Missense	distal	-6	no	19.631	18.475	EPSD	ICGC	19.028	Loss
STE_STE20_PAKA_PAK1_ST	Q15746	MYLK	Q13153	PAK1	S1063	E1066Q	1066	Missense	distal	3	no	19.809	20.235	EPSD	ICGC;COSMIC	19.028	Up-regulation
STE_STE20_PAKA_PAK1_ST	Q15746	MYLK	Q13153	PAK1	S1063	E1066V	1066	Missense	distal	3	no	19.809	21.034	EPSD	ICGC;COSMIC;GDSC	19.028	Up-regulation
STE_STE20_PAKA_PAK1_ST	Q15746	MYLK	Q13153	PAK1	S1208	P1211A	1211	Missense	distal	3	no	28.909	28.242	EPSD	ICGC;COSMIC	19.028	Down-regulation
STE_STE20_PAKA_PAK1_ST	Q15746	MYLK	Q13153	PAK1	S1208	S1208I	1208	Missense	central	0	yes	28.909	0.000	EPSD	ICGC;COSMIC	19.028	Loss
STE_STE20_PAKA_PAK1_ST	Q15746	MYLK	Q13153	PAK1	S1208	R1204L	1204	Missense	distal	-4	no	28.909	28.596	EPSD	ICGC;COSMIC	19.028	Down-regulation
STE_STE20_PAKA_PAK1_ST	Q15746	MYLK	Q13153	PAK1	S1209	P1211A	1211	Missense	proximal	2	no	20.433	20.692	EPSD	ICGC;COSMIC	19.028	Up-regulation
STE_STE20_PAKA_PAK1_ST	Q15746	MYLK	Q13153	PAK1	S1209	S1208I	1208	Missense	proximal	-1	no	20.433	20.057	EPSD	ICGC;COSMIC	19.028	Down-regulation
STE_STE20_PAKA_PAK1_ST	Q15746	MYLK	Q13153	PAK1	S1209	R1204L	1204	Missense	distal	-5	no	20.433	21.223	EPSD	ICGC;COSMIC	19.028	Up-regulation
STE_STE20_PAKA_PAK1_ST	Q15746	MYLK	Q13153	PAK1	S1570	H1577Q	1577	Missense	distal	7	no	21.141	21.089	EPSD	ICGC	19.028	Down-regulation
STE_STE20_PAKA_PAK1_ST	P08670	VIM	Q13153	PAK1	S26	P24L	24	Missense	proximal	-2	no	24.597	19.558	EPSD	ICGC;COSMIC	19.028	Down-regulation
STE_STE20_PAKA_PAK1_ST	P08670	VIM	Q13153	PAK1	S26	V31A	31	Missense	distal	5	no	24.597	24.596	EPSD	ICGC	19.028	Down-regulation
STE_STE20_PAKA_PAK1_ST	P08670	VIM	Q13153	PAK1	S34	V31A	31	Missense	distal	-3	no	14.800	22.062	EPSD	ICGC	19.028	Gain
STE_STE20_PAKA_PAK1_ST	P08670	VIM	Q13153	PAK1	T35	V31A	31	Missense	distal	-4	no	19.576	19.764	EPSD	ICGC	19.028	Up-regulation
STE_STE20_PAKA_PAK1_ST	P08670	VIM	Q13153	PAK1	T35	R36S	36	Missense	proximal	1	no	19.576	19.173	EPSD	ICGC;COSMIC	19.028	Down-regulation
STE_STE20_PAKA_PAK1_ST	P08670	VIM	Q13153	PAK1	S39	R45H	45	Missense	distal	6	no	23.474	23.918	EPSD	ICGC	19.028	Up-regulation
STE_STE20_PAKA_PAK1_ST	P08670	VIM	Q13153	PAK1	S39	R36S	36	Missense	distal	-3	no	23.474	14.802	EPSD	ICGC;COSMIC	19.028	Loss
STE_STE20_PAKA_PAK1_ST	P08670	VIM	Q13153	PAK1	S51	R45H	45	Missense	distal	-6	no	20.183	19.324	EPSD	ICGC	19.028	Down-regulation
STE_STE20_PAKA_PAK1_ST	P08670	VIM	Q13153	PAK1	S51	S55L	55	Missense	distal	4	no	20.183	20.976	EPSD	ICGC	19.028	Up-regulation
STE_STE20_PAKA_PAK1_ST	P08670	VIM	Q13153	PAK1	S51	A54G	54	Missense	distal	3	no	20.183	21.214	EPSD	ICGC	19.028	Up-regulation
STE_STE20_PAKA_PAK1_ST	P08670	VIM	Q13153	PAK1	S56	S55L	55	Missense	proximal	-1	no	22.375	23.323	PhosphoSitePlus	ICGC	19.028	Up-regulation
STE_STE20_PAKA_PAK1_ST	P08670	VIM	Q13153	PAK1	S56	A54G	54	Missense	proximal	-2	no	22.375	20.630	PhosphoSitePlus	ICGC	19.028	Down-regulation
STE_STE20_PAKA_PAK1_ST	P08670	VIM	Q13153	PAK1	S56	A62V	62	Missense	distal	6	no	22.375	22.696	PhosphoSitePlus	ICGC	19.028	Up-regulation
STE_STE20_PAKA_PAK1_ST	P08670	VIM	Q13153	PAK1	S66	A62V	62	Missense	distal	-4	no	25.465	25.276	EPSD	ICGC	19.028	Down-regulation
STE_STE20_PAKA_PAK1_ST	P08670	VIM	Q13153	PAK1	S430	L428P	428	Missense	proximal	-2	no	14.332	19.371	EPSD	ICGC;COSMIC	19.028	Gain
Other_WNK_WNK1_ST	O94913	PCF11	Q9H4A3	WNK1	S33	S33I	33	Missense	central	0	yes	0.000	0.000	EPSD	ICGC	0.000	Loss
Other_WNK_WNK1_ST	O94913	PCF11	Q9H4A3	WNK1	S56	S56F	56	Missense	central	0	yes	0.000	0.000	EPSD	ICGC;COSMIC	0.000	Loss
Other_WNK_WNK1_ST	O94913	PCF11	Q9H4A3	WNK1	S169	P163T	163	Missense	distal	-6	no	-0.001	0.000	EPSD	ICGC;COSMIC	0.000	Gain
Other_WNK_WNK1_ST	O94913	PCF11	Q9H4A3	WNK1	S239	S239I	239	Missense	central	0	yes	0.000	0.000	EPSD	ICGC	0.000	Loss
Other_WNK_WNK1_ST	O94913	PCF11	Q9H4A3	WNK1	S379	P373L	373	Missense	distal	-6	no	0.000	0.001	EPSD	ICGC	0.000	Up-regulation
Other_WNK_WNK1_ST	O94913	PCF11	Q9H4A3	WNK1	S379	P373S	373	Missense	distal	-6	no	0.000	0.001	EPSD	ICGC	0.000	Up-regulation
Other_WNK_WNK1_ST	O94913	PCF11	Q9H4A3	WNK1	T459	D458G	458	Missense	proximal	-1	no	0.001	0.000	EPSD	ICGC;COSMIC	0.000	Down-regulation
Other_WNK_WNK1_ST	O94913	PCF11	Q9H4A3	WNK1	T461	T461R	461	Missense	central	0	yes	0.000	0.000	EPSD	ICGC;COSMIC	0.000	Loss
Other_WNK_WNK1_ST	O94913	PCF11	Q9H4A3	WNK1	S494	S494A	494	Missense	central	0	yes	0.000	0.000	EPSD	ICGC	0.000	Loss
Other_WNK_WNK1_ST	O94913	PCF11	Q9H4A3	WNK1	S514	S514L	514	Missense	central	0	yes	0.000	0.000	EPSD	ICGC;COSMIC	0.000	Loss
Other_WNK_WNK1_ST	O94913	PCF11	Q9H4A3	WNK1	S627	S627I	627	Missense	central	0	yes	0.000	0.000	EPSD	ICGC	0.000	Loss
Other_WNK_WNK1_ST	O94913	PCF11	Q9H4A3	WNK1	T738	N739S	739	Missense	proximal	1	no	0.001	0.000	EPSD	ICGC;COSMIC	0.000	Down-regulation
Other_WNK_WNK1_ST	O94913	PCF11	Q9H4A3	WNK1	S1477	S1477P	1477	Missense	central	0	yes	0.000	0.000	EPSD	ICGC;COSMIC	0.000	Loss
Other_WNK_WNK1_ST	O94913	PCF11	Q9H4A3	WNK1	T1485	T1485A	1485	Missense	central	0	yes	0.000	0.000	EPSD	ICGC;COSMIC	0.000	Loss
Other_WNK_WNK1_ST	O94913	PCF11	Q9H4A3	WNK1	S1495	S1495N	1495	Missense	central	0	yes	0.000	0.000	EPSD	ICGC;COSMIC	0.000	Loss
Other_WNK_WNK1_ST	O95747	OXSR1	Q9H4A3	WNK1	T304	T304I	304	Missense	central	0	yes	0.001	0.000	EPSD	ICGC;COSMIC	0.000	Loss
Other_WNK_WNK1_ST	O95747	OXSR1	Q9H4A3	WNK1	S312	S312Y	312	Missense	central	0	yes	0.000	0.000	EPSD	ICGC;COSMIC	0.000	Loss
Other_WNK_WNK1_ST	O95747	OXSR1	Q9H4A3	WNK1	S355	S355L	355	Missense	central	0	yes	0.000	0.000	EPSD	ICGC;COSMIC	0.000	Loss
Other_WNK_WNK1_ST	Q9H4A3	WNK1	Q9H4A3	WNK1	T12	T12A	12	Missense	central	0	yes	0.000	0.000	EPSD	ICGC;COSMIC	0.000	Loss
Other_WNK_WNK1_ST	Q9H4A3	WNK1	Q9H4A3	WNK1	S29	P23L	23	Missense	distal	-6	no	-0.001	0.000	EPSD	ICGC;COSMIC	0.000	Gain
Other_WNK_WNK1_ST	Q9H4A3	WNK1	Q9H4A3	WNK1	S34	S34C	34	Missense	central	0	yes	0.000	0.000	EPSD	ICGC;COSMIC	0.000	Loss
Other_WNK_WNK1_ST	Q9H4A3	WNK1	Q9H4A3	WNK1	T51	R55G	55	Missense	distal	4	no	0.001	0.000	EPSD	ICGC;COSMIC	0.000	Down-regulation
Other_WNK_WNK1_ST	Q9H4A3	WNK1	Q9H4A3	WNK1	T60	T60I	60	Missense	central	0	yes	0.000	0.000	EPSD	ICGC;COSMIC	0.000	Loss
Other_WNK_WNK1_ST	Q9H4A3	WNK1	Q9H4A3	WNK1	T71	A70V	70	Missense	proximal	-1	no	0.001	0.000	EPSD	ICGC;COSMIC	0.000	Down-regulation
Other_WNK_WNK1_ST	Q9H4A3	WNK1	Q9H4A3	WNK1	T71	R66S	66	Missense	distal	-5	no	0.001	0.000	EPSD	ICGC;GDSC;CCLE	0.000	Down-regulation
Other_WNK_WNK1_ST	Q9H4A3	WNK1	Q9H4A3	WNK1	T72	R66S	66	Missense	distal	-6	no	0.001	0.000	EPSD	ICGC;GDSC;CCLE	0.000	Down-regulation
Other_WNK_WNK1_ST	Q9H4A3	WNK1	Q9H4A3	WNK1	T73	R66S	66	Missense	distal	-7	no	0.001	0.000	EPSD	ICGC;GDSC;CCLE	0.000	Down-regulation
Other_WNK_WNK1_ST	Q9H4A3	WNK1	Q9H4A3	WNK1	S185	P179S	179	Missense	distal	-6	no	-0.001	0.000	EPSD	ICGC;COSMIC	0.000	Gain
Other_WNK_WNK1_ST	Q9H4A3	WNK1	Q9H4A3	WNK1	S596	S596F	596	Missense	central	0	yes	0.000	0.000	EPSD	ICGC;COSMIC	0.000	Loss
Other_WNK_WNK1_ST	Q9H4A3	WNK1	Q9H4A3	WNK1	S1105	S1105R	1105	Missense	central	0	yes	0.001	0.000	EPSD	ICGC	0.000	Loss
Other_WNK_WNK1_ST	Q9H4A3	WNK1	Q9H4A3	WNK1	T1889	T1889A	1889	Missense	central	0	yes	0.000	0.000	EPSD	ICGC	0.000	Loss
Other_WNK_WNK1_ST	Q9H4A3	WNK1	Q9H4A3	WNK1	S1899	S1899F	1899	Missense	central	0	yes	0.000	0.000	EPSD	ICGC	0.000	Loss
Other_WNK_WNK1_ST	Q9UHW9	SLC12A6	Q9H4A3	WNK1	T20	P19H	19	Missense	proximal	-1	no	0.000	0.001	EPSD	ICGC;COSMIC	0.000	Up-regulation
Other_WNK_WNK1_ST	Q9UHW9	SLC12A6	Q9H4A3	WNK1	T20	P19L	19	Missense	proximal	-1	no	0.000	0.001	EPSD	ICGC;COSMIC	0.000	Up-regulation
Other_WNK_WNK1_ST	Q9UHW9	SLC12A6	Q9H4A3	WNK1	S36	S36L	36	Missense	central	0	yes	0.000	0.000	EPSD	ICGC;COSMIC	0.000	Loss
Other_WNK_WNK1_ST	Q9UHW9	SLC12A6	Q9H4A3	WNK1	S37	S37P	37	Missense	central	0	yes	0.000	0.000	EPSD	ICGC;COSMIC	0.000	Loss
Other_WNK_WNK1_ST	Q9UHW9	SLC12A6	Q9H4A3	WNK1	S50	S50R	50	Missense	central	0	yes	0.000	0.000	EPSD	ICGC	0.000	Loss
Other_WNK_WNK1_ST	Q9UHW9	SLC12A6	Q9H4A3	WNK1	T54	T54K	54	Missense	central	0	yes	0.000	0.000	EPSD	ICGC;COSMIC	0.000	Loss
Other_WNK_WNK1_ST	Q9UHW9	SLC12A6	Q9H4A3	WNK1	T98	T98N	98	Missense	central	0	yes	0.000	0.000	EPSD	ICGC	0.000	Loss
Other_WNK_WNK1_ST	Q9UEW8	STK39	Q9H4A3	WNK1	T32	T32K	32	Missense	central	0	yes	0.000	0.000	EPSD	ICGC	0.000	Loss
Other_WNK_WNK1_ST	Q9UEW8	STK39	Q9H4A3	WNK1	T101	T101N	101	Missense	central	0	yes	0.000	0.000	EPSD	ICGC;COSMIC	0.000	Loss
Other_WNK_WNK1_ST	Q9UEW8	STK39	Q9H4A3	WNK1	S114	A112V	112	Missense	proximal	-2	no	0.001	0.000	EPSD	ICGC	0.000	Down-regulation
Other_WNK_WNK1_ST	Q9UEW8	STK39	Q9H4A3	WNK1	S114	S117N	117	Missense	distal	3	no	0.001	0.000	EPSD	ICGC;COSMIC	0.000	Down-regulation
Other_WNK_WNK1_ST	Q9UEW8	STK39	Q9H4A3	WNK1	S127	S127C	127	Missense	central	0	yes	0.000	0.000	EPSD	ICGC;COSMIC	0.000	Loss
TK_InsR_INSR_Y	P35568	IRS1	P06213	INSR	Y431	D437Y	437	Missense	distal	6	no	13.127	12.897	EPSD	ICGC;COSMIC	10.312	Down-regulation
TK_InsR_INSR_Y	P35568	IRS1	P06213	INSR	Y551	A557D	557	Missense	distal	6	no	10.566	10.848	EPSD	ICGC	10.312	Up-regulation
TK_InsR_INSR_Y	P35568	IRS1	P06213	INSR	Y582	A575T	575	Missense	distal	-7	no	9.979	10.610	EPSD	ICGC;COSMIC	10.312	Gain
TK_InsR_INSR_Y	P35568	IRS1	P06213	INSR	Y632	P634S	634	Missense	proximal	2	no	13.734	15.561	EPSD	ICGC;COSMIC	10.312	Up-regulation
TK_InsR_INSR_Y	P35568	IRS1	P06213	INSR	Y632	Y632C	632	Missense	central	0	yes	13.734	0.000	EPSD	ICGC;COSMIC	10.312	Loss
TK_InsR_INSR_Y	P35568	IRS1	P06213	INSR	Y632	K627N	627	Missense	distal	-5	no	13.734	14.174	EPSD	ICGC;COSMIC	10.312	Up-regulation
TK_InsR_INSR_Y	P35568	IRS1	P06213	INSR	Y750	G752S	752	Missense	proximal	2	no	10.498	11.948	EPSD	ICGC;COSMIC	10.312	Up-regulation
TK_InsR_INSR_Y	P35568	IRS1	P06213	INSR	Y750	P746T	746	Missense	distal	-4	no	10.498	11.747	EPSD	ICGC	10.312	Up-regulation
TK_InsR_INSR_Y	P35568	IRS1	P06213	INSR	Y750	P746S	746	Missense	distal	-4	no	10.498	12.632	EPSD	ICGC	10.312	Up-regulation
TK_InsR_INSR_Y	P35568	IRS1	P06213	INSR	Y750	D748N	748	Missense	proximal	-2	no	10.498	8.359	EPSD	ICGC	10.312	Loss
TK_InsR_INSR_Y	P35568	IRS1	P06213	INSR	Y941	E939D	939	Missense	proximal	-2	no	20.361	21.652	EPSD	ICGC	10.312	Up-regulation
TK_InsR_INSR_Y	P35568	IRS1	P06213	INSR	Y1001	D1003N	1003	Missense	proximal	2	no	13.473	12.612	EPSD	ICGC;COSMIC	10.312	Down-regulation
TK_InsR_INSR_Y	P35568	IRS1	P06213	INSR	Y1229	Q1235H	1235	Missense	distal	6	no	10.599	10.467	EPSD	ICGC;COSMIC	10.312	Down-regulation
TK_InsR_INSR_Y	P53004	BLVRA	P06213	INSR	Y83	A90S	90	Missense	distal	7	no	16.524	16.531	EPSD	ICGC	10.312	Up-regulation
TK_InsR_INSR_Y	P53004	BLVRA	P06213	INSR	Y198	Y198S	198	Missense	central	0	yes	12.819	0.000	EPSD;PhosphoSitePlus	ICGC;COSMIC	10.312	Loss
TK_InsR_INSR_Y	P53004	BLVRA	P06213	INSR	Y228	S235T	235	Missense	distal	7	no	11.369	11.365	PhosphoSitePlus;EPSD	ICGC;COSMIC	10.312	Down-regulation
TK_InsR_INSR_Y	Q13480	GAB1	P06213	INSR	Y285	G292W	292	Missense	distal	7	no	13.084	13.072	EPSD;PhosphoSitePlus	ICGC;COSMIC	10.312	Down-regulation
TK_InsR_INSR_Y	Q13480	GAB1	P06213	INSR	Y373	G379W	379	Missense	distal	6	no	11.973	11.605	EPSD;PhosphoSitePlus	ICGC;COSMIC	10.312	Down-regulation
TK_InsR_INSR_Y	Q13480	GAB1	P06213	INSR	Y373	P376T	376	Missense	distal	3	no	11.973	12.555	EPSD;PhosphoSitePlus	ICGC;COSMIC	10.312	Up-regulation
TK_InsR_INSR_Y	Q13480	GAB1	P06213	INSR	Y447	V448I	448	Missense	proximal	1	no	17.503	16.391	EPSD;PhosphoSitePlus	ICGC;COSMIC	10.312	Down-regulation
TK_InsR_INSR_Y	Q13480	GAB1	P06213	INSR	Y447	D444Y	444	Missense	distal	-3	no	17.503	14.448	EPSD;PhosphoSitePlus	ICGC	10.312	Down-regulation
TK_InsR_INSR_Y	Q13480	GAB1	P06213	INSR	Y447	M450I	450	Missense	distal	3	no	17.503	17.246	EPSD;PhosphoSitePlus	ICGC	10.312	Down-regulation
TK_InsR_INSR_Y	Q13017	ARHGAP5	P06213	INSR	Y630	R635W	635	Missense	distal	5	no	9.818	10.954	EPSD	ICGC;COSMIC;GDSC	10.312	Gain
TK_InsR_INSR_Y	Q13017	ARHGAP5	P06213	INSR	Y1091	M1085V	1085	Missense	distal	-6	no	17.232	17.233	EPSD	ICGC;COSMIC	10.312	Up-regulation
TK_InsR_INSR_Y	Q13017	ARHGAP5	P06213	INSR	Y1091	P1087L	1087	Missense	distal	-4	no	17.232	16.417	EPSD	ICGC;COSMIC	10.312	Down-regulation
TK_InsR_INSR_Y	Q13017	ARHGAP5	P06213	INSR	Y1109	E1107D	1107	Missense	proximal	-2	no	11.160	12.451	EPSD	ICGC;COSMIC	10.312	Up-regulation
TK_InsR_INSR_Y	Q13017	ARHGAP5	P06213	INSR	Y1109	S1105F	1105	Missense	distal	-4	no	11.160	7.672	EPSD	ICGC;COSMIC	10.312	Loss
TK_InsR_INSR_Y	Q99704	DOK1	P06213	INSR	Y315	D312G	312	Missense	distal	-3	no	14.208	12.279	EPSD	ICGC	10.312	Down-regulation
TK_InsR_INSR_Y	Q99704	DOK1	P06213	INSR	Y315	S321I	321	Missense	distal	6	no	14.208	13.857	EPSD	ICGC;COSMIC	10.312	Down-regulation
TK_InsR_INSR_Y	P60484	PTEN	P06213	INSR	Y174	Y177S	177	Missense	distal	3	no	9.762	10.363	PhosphoSitePlus;EPSD	ICGC;COSMIC	10.312	Gain
TK_InsR_INSR_Y	P60484	PTEN	P06213	INSR	Y174	Y178S	178	Missense	distal	4	no	9.762	10.561	PhosphoSitePlus;EPSD	ICGC;COSMIC	10.312	Gain
TK_InsR_INSR_Y	P60484	PTEN	P06213	INSR	Y315	D312Y	312	Missense	distal	-3	no	12.360	9.305	EPSD	ICGC	10.312	Loss
TK_InsR_INSR_Y	P29350	PTPN6	P06213	INSR	Y176	T177M	177	Missense	proximal	1	no	10.367	10.093	EPSD	ICGC	10.312	Loss
TK_InsR_INSR_Y	Q9P219	CCDC88C	P06213	INSR	Y1699	D1694E	1694	Missense	distal	-5	no	11.100	10.838	EPSD	ICGC	10.312	Down-regulation
TK_InsR_INSR_Y	Q9P219	CCDC88C	P06213	INSR	Y1699	D1694N	1694	Missense	distal	-5	no	11.100	10.525	EPSD	ICGC	10.312	Down-regulation
TK_InsR_INSR_Y	P25963	NFKBIA	P06213	INSR	Y42	E48Q	48	Missense	distal	6	no	14.355	14.214	PhosphoSitePlus	ICGC;COSMIC	10.312	Down-regulation
TK_InsR_INSR_Y	P25963	NFKBIA	P06213	INSR	Y42	E48D	48	Missense	distal	6	no	14.355	14.361	PhosphoSitePlus	ICGC;COSMIC	10.312	Up-regulation
TK_InsR_INSR_Y	P25963	NFKBIA	P06213	INSR	Y42	K38T	38	Missense	distal	-4	no	14.355	14.995	PhosphoSitePlus	ICGC	10.312	Up-regulation
STE_STE-Unique_MAP3K8_ST	P35241	RDX	P41279	MAP3K8	S249	D252E	252	Missense	distal	3	no	22.416	23.670	EPSD	ICGC	13.250	Up-regulation
STE_STE-Unique_MAP3K8_ST	P35241	RDX	P41279	MAP3K8	T564	A557E	557	Missense	distal	-7	no	27.578	27.414	PhosphoSitePlus	ICGC	13.250	Down-regulation
STE_STE-Unique_MAP3K8_ST	Q14653	IRF3	P41279	MAP3K8	T32	R35H	35	Missense	distal	3	no	13.813	8.998	EPSD	ICGC	13.250	Loss
STE_STE-Unique_MAP3K8_ST	Q14653	IRF3	P41279	MAP3K8	S97	P103S	103	Missense	distal	6	no	13.211	13.539	EPSD	ICGC;COSMIC	13.250	Gain
STE_STE-Unique_MAP3K8_ST	P15311	EZR	P41279	MAP3K8	S249	F255L	255	Missense	distal	6	no	22.102	22.099	EPSD	ICGC;COSMIC	13.250	Down-regulation
STE_STE-Unique_MAP3K8_ST	P15311	EZR	P41279	MAP3K8	S249	D252H	252	Missense	distal	3	no	22.102	21.948	EPSD	ICGC	13.250	Down-regulation
STE_STE-Unique_MAP3K8_ST	P15311	EZR	P41279	MAP3K8	T533	T533M	533	Missense	central	0	yes	20.836	0.000	EPSD	ICGC	13.250	Loss
STE_STE-Unique_MAP3K8_ST	P15311	EZR	P41279	MAP3K8	S536	T533M	533	Missense	distal	-3	no	16.296	23.993	EPSD	ICGC	13.250	Up-regulation
STE_STE-Unique_MAP3K8_ST	P15311	EZR	P41279	MAP3K8	S539	E544Q	544	Missense	distal	5	no	16.550	16.197	EPSD	ICGC	13.250	Down-regulation
STE_STE-Unique_MAP3K8_ST	P15311	EZR	P41279	MAP3K8	S539	T533M	533	Missense	distal	-6	no	16.550	15.782	EPSD	ICGC	13.250	Down-regulation
STE_STE-Unique_MAP3K8_ST	P15311	EZR	P41279	MAP3K8	T567	T567M	567	Missense	central	0	yes	30.912	0.000	PhosphoSitePlus	ICGC;COSMIC	13.250	Loss
STE_STE-Unique_MAP3K8_ST	P15311	EZR	P41279	MAP3K8	T567	Q573K	573	Missense	distal	6	no	30.912	30.281	PhosphoSitePlus	ICGC	13.250	Down-regulation
STE_STE-Unique_MAP3K8_ST	P00519	ABL1	P41279	MAP3K8	S50	R47C	47	Missense	distal	-3	no	20.484	10.028	EPSD	ICGC;COSMIC	13.250	Loss
STE_STE-Unique_MAP3K8_ST	P00519	ABL1	P41279	MAP3K8	S50	A56T	56	Missense	distal	6	no	20.484	20.534	EPSD	ICGC;COSMIC	13.250	Up-regulation
STE_STE-Unique_MAP3K8_ST	P00519	ABL1	P41279	MAP3K8	S50	A46T	46	Missense	distal	-4	no	20.484	20.257	EPSD	ICGC;COSMIC	13.250	Down-regulation
STE_STE-Unique_MAP3K8_ST	P00519	ABL1	P41279	MAP3K8	T83	K87N	87	Missense	distal	4	no	11.232	13.840	EPSD	ICGC;COSMIC	13.250	Gain
STE_STE-Unique_MAP3K8_ST	P00519	ABL1	P41279	MAP3K8	T117	V111L	111	Missense	distal	-6	no	13.586	13.039	EPSD	ICGC;COSMIC	13.250	Loss
STE_STE-Unique_MAP3K8_ST	P00519	ABL1	P41279	MAP3K8	T117	V119F	119	Missense	proximal	2	no	13.586	13.497	EPSD	ICGC	13.250	Down-regulation
STE_STE-Unique_MAP3K8_ST	P00519	ABL1	P41279	MAP3K8	S164	G169W	169	Missense	distal	5	no	15.932	15.856	EPSD	ICGC;COSMIC	13.250	Down-regulation
STE_STE-Unique_MAP3K8_ST	P00519	ABL1	P41279	MAP3K8	S164	S164L	164	Missense	central	0	yes	15.932	0.000	EPSD	ICGC;CCLE	13.250	Loss
STE_STE-Unique_MAP3K8_ST	P00519	ABL1	P41279	MAP3K8	S164	R170G	170	Missense	distal	6	no	15.932	14.536	EPSD	ICGC;COSMIC	13.250	Down-regulation
STE_STE-Unique_MAP3K8_ST	P00519	ABL1	P41279	MAP3K8	S164	R161M	161	Missense	distal	-3	no	15.932	9.821	EPSD	ICGC;COSMIC	13.250	Loss
STE_STE-Unique_MAP3K8_ST	P00519	ABL1	P41279	MAP3K8	S620	R617C	617	Missense	distal	-3	no	13.284	2.829	EPSD	ICGC;COSMIC	13.250	Loss
STE_STE-Unique_MAP3K8_ST	P00519	ABL1	P41279	MAP3K8	S620	R617H	617	Missense	distal	-3	no	13.284	2.374	EPSD	ICGC;COSMIC	13.250	Loss
STE_STE-Unique_MAP3K8_ST	P00519	ABL1	P41279	MAP3K8	S620	M624I	624	Missense	distal	4	no	13.284	15.044	EPSD	ICGC;COSMIC	13.250	Up-regulation
STE_STE-Unique_MAP3K8_ST	P00519	ABL1	P41279	MAP3K8	T649	S642G	642	Missense	distal	-7	no	18.109	17.419	EPSD	ICGC	13.250	Down-regulation
STE_STE-Unique_MAP3K8_ST	P00519	ABL1	P41279	MAP3K8	S691	T692M	692	Missense	proximal	1	no	9.047	14.477	EPSD	ICGC	13.250	Gain
STE_STE-Unique_MAP3K8_ST	P00519	ABL1	P41279	MAP3K8	T692	H685R	685	Missense	distal	-7	no	16.053	16.588	EPSD	ICGC;COSMIC	13.250	Up-regulation
STE_STE-Unique_MAP3K8_ST	P00519	ABL1	P41279	MAP3K8	T692	K688N	688	Missense	distal	-4	no	16.053	15.193	EPSD	ICGC;COSMIC	13.250	Down-regulation
STE_STE-Unique_MAP3K8_ST	P00519	ABL1	P41279	MAP3K8	T692	T692M	692	Missense	central	0	yes	16.053	0.000	EPSD	ICGC	13.250	Loss
STE_STE-Unique_MAP3K8_ST	P00519	ABL1	P41279	MAP3K8	S718	R712H	712	Missense	distal	-6	no	20.494	20.030	EPSD	ICGC;COSMIC	13.250	Down-regulation
STE_STE-Unique_MAP3K8_ST	P00519	ABL1	P41279	MAP3K8	S718	R715H	715	Missense	distal	-3	no	20.494	9.584	EPSD	ICGC;COSMIC	13.250	Loss
STE_STE-Unique_MAP3K8_ST	P00519	ABL1	P41279	MAP3K8	S718	V722F	722	Missense	distal	4	no	20.494	19.519	EPSD	ICGC	13.250	Down-regulation
STE_STE-Unique_MAP3K8_ST	P00519	ABL1	P41279	MAP3K8	S718	K711N	711	Missense	distal	-7	no	20.494	20.760	EPSD	ICGC;COSMIC	13.250	Up-regulation
STE_STE-Unique_MAP3K8_ST	P00519	ABL1	P41279	MAP3K8	S718	R715C	715	Missense	distal	-3	no	20.494	10.039	EPSD	ICGC;CCLE	13.250	Loss
STE_STE-Unique_MAP3K8_ST	P00519	ABL1	P41279	MAP3K8	T735	D728Y	728	Missense	distal	-7	no	34.614	34.378	PhosphoSitePlus	ICGC	13.250	Down-regulation
STE_STE-Unique_MAP3K8_ST	P00519	ABL1	P41279	MAP3K8	T735	S742F	742	Missense	distal	7	no	34.614	33.604	PhosphoSitePlus	ICGC;COSMIC	13.250	Down-regulation
STE_STE-Unique_MAP3K8_ST	P00519	ABL1	P41279	MAP3K8	T751	D748Y	748	Missense	distal	-3	no	15.410	15.085	EPSD	ICGC	13.250	Down-regulation
STE_STE-Unique_MAP3K8_ST	P00519	ABL1	P41279	MAP3K8	T823	S828L	828	Missense	distal	5	no	22.219	22.031	EPSD	ICGC;COSMIC	13.250	Down-regulation
STE_STE-Unique_MAP3K8_ST	P00519	ABL1	P41279	MAP3K8	T823	A825P	825	Missense	proximal	2	no	22.219	22.422	EPSD	ICGC;COSMIC	13.250	Up-regulation
STE_STE-Unique_MAP3K8_ST	P16220	CREB1	P41279	MAP3K8	S133	D140A	140	Missense	distal	7	no	36.386	36.265	PhosphoSitePlus	ICGC;COSMIC	13.250	Down-regulation
STE_STE-Unique_MAP3K8_ST	P16220	CREB1	P41279	MAP3K8	S143	D140A	140	Missense	distal	-3	no	18.032	15.521	EPSD	ICGC;COSMIC	13.250	Down-regulation
STE_STE-Unique_MAP3K8_ST	Q04637	EIF4G1	P41279	MAP3K8	T207	P208S	208	Missense	proximal	1	no	21.065	18.333	EPSD	ICGC;COSMIC	13.250	Down-regulation
STE_STE-Unique_MAP3K8_ST	Q04637	EIF4G1	P41279	MAP3K8	T207	P208H	208	Missense	proximal	1	no	21.065	20.357	EPSD	ICGC;GDSC;CCLE	13.250	Down-regulation
STE_STE-Unique_MAP3K8_ST	Q04637	EIF4G1	P41279	MAP3K8	S1145	E1152D	1152	Missense	distal	7	no	19.747	19.794	EPSD	ICGC;COSMIC	13.250	Up-regulation
STE_STE-Unique_MAP3K8_ST	Q04637	EIF4G1	P41279	MAP3K8	S1147	E1152D	1152	Missense	distal	5	no	25.856	25.572	PhosphoSitePlus	ICGC;COSMIC	13.250	Down-regulation
STE_STE-Unique_MAP3K8_ST	Q04637	EIF4G1	P41279	MAP3K8	S1164	R1166H	1166	Missense	proximal	2	no	15.969	15.310	EPSD	ICGC;COSMIC	13.250	Down-regulation
STE_STE-Unique_MAP3K8_ST	Q04637	EIF4G1	P41279	MAP3K8	T1179	R1184Q	1184	Missense	distal	5	no	26.900	27.437	EPSD	ICGC;COSMIC	13.250	Up-regulation
STE_STE-Unique_MAP3K8_ST	Q04637	EIF4G1	P41279	MAP3K8	T1182	R1184Q	1184	Missense	proximal	2	no	16.543	16.096	EPSD	ICGC;COSMIC	13.250	Down-regulation
STE_STE-Unique_MAP3K8_ST	Q04637	EIF4G1	P41279	MAP3K8	S1185	R1184Q	1184	Missense	proximal	-1	no	13.858	11.503	EPSD	ICGC;COSMIC	13.250	Loss
STE_STE-Unique_MAP3K8_ST	Q04637	EIF4G1	P41279	MAP3K8	S1187	R1184Q	1184	Missense	distal	-3	no	25.950	17.175	EPSD	ICGC;COSMIC	13.250	Down-regulation
STE_STE-Unique_MAP3K8_ST	Q04637	EIF4G1	P41279	MAP3K8	S1194	S1199C	1199	Missense	distal	5	no	14.389	14.500	EPSD	ICGC;COSMIC	13.250	Up-regulation
STE_STE-Unique_MAP3K8_ST	Q04637	EIF4G1	P41279	MAP3K8	S1194	S1199F	1199	Missense	distal	5	no	14.389	14.430	EPSD	ICGC;COSMIC	13.250	Up-regulation
STE_STE-Unique_MAP3K8_ST	Q13541	EIF4EBP1	P41279	MAP3K8	T70	P71A	71	Missense	proximal	1	no	22.215	19.428	PhosphoSitePlus	ICGC;COSMIC	13.250	Down-regulation
STE_STE-Unique_MAP3K8_ST	Q13541	EIF4EBP1	P41279	MAP3K8	T70	P71H	71	Missense	proximal	1	no	22.215	21.508	PhosphoSitePlus	ICGC;COSMIC	13.250	Down-regulation
STE_STE-Unique_MAP3K8_ST	P53350	PLK1	P41279	MAP3K8	S137	E140Q	140	Missense	distal	3	no	24.840	25.602	EPSD;PhosphoSitePlus	ICGC;COSMIC	13.250	Up-regulation
STE_STE-Unique_MAP3K8_ST	Q02750	MAP2K1	P41279	MAP3K8	S218	G225C	225	Missense	distal	7	no	35.306	35.073	EPSD;PhosphoSitePlus	ICGC	13.250	Down-regulation
STE_STE-Unique_MAP3K8_ST	Q02750	MAP2K1	P41279	MAP3K8	S218	L215I	215	Missense	distal	-3	no	35.306	34.145	EPSD;PhosphoSitePlus	ICGC;COSMIC	13.250	Down-regulation
STE_STE-Unique_MAP3K8_ST	Q02750	MAP2K1	P41279	MAP3K8	S222	G225C	225	Missense	distal	3	no	29.794	28.271	PhosphoSitePlus;EPSD	ICGC	13.250	Down-regulation
STE_STE-Unique_MAP3K8_ST	Q02750	MAP2K1	P41279	MAP3K8	S222	L215I	215	Missense	distal	-7	no	29.794	29.669	PhosphoSitePlus;EPSD	ICGC;COSMIC	13.250	Down-regulation
STE_STE-Unique_MAP3K8_ST	Q02750	MAP2K1	P41279	MAP3K8	S231	P232R	232	Missense	proximal	1	no	15.435	18.686	EPSD	ICGC	13.250	Up-regulation
STE_STE-Unique_MAP3K8_ST	Q02750	MAP2K1	P41279	MAP3K8	S231	R234I	234	Missense	distal	3	no	15.435	9.739	EPSD	ICGC	13.250	Loss
STE_STE-Unique_MAP3K8_ST	Q02750	MAP2K1	P41279	MAP3K8	S231	G225C	225	Missense	distal	-6	no	15.435	15.202	EPSD	ICGC	13.250	Down-regulation
STE_STE-Unique_MAP3K8_ST	P26038	MSN	P41279	MAP3K8	S249	W242L	242	Missense	distal	-7	no	23.574	23.806	EPSD	ICGC	13.250	Up-regulation
STE_STE-Unique_MAP3K8_ST	P26038	MSN	P41279	MAP3K8	S249	D252N	252	Missense	distal	3	no	23.574	25.345	EPSD	ICGC;COSMIC	13.250	Up-regulation
STE_STE-Unique_MAP3K8_ST	P26038	MSN	P41279	MAP3K8	S504	D497Y	497	Missense	distal	-7	no	21.992	21.756	EPSD	ICGC	13.250	Down-regulation
STE_STE-Unique_MAP3K8_ST	P26038	MSN	P41279	MAP3K8	T526	S527L	527	Missense	proximal	1	no	9.511	15.251	EPSD	ICGC;GDSC;CCLE	13.250	Gain
STE_STE-Unique_MAP3K8_ST	P26038	MSN	P41279	MAP3K8	S536	M543I	543	Missense	distal	7	no	13.986	14.076	EPSD	ICGC	13.250	Up-regulation
STE_STE-Unique_MAP3K8_ST	P26038	MSN	P41279	MAP3K8	T558	D554N	554	Missense	distal	-4	no	29.457	29.321	PhosphoSitePlus	ICGC;COSMIC	13.250	Down-regulation
STE_STE-Unique_MAP3K8_ST	P26038	MSN	P41279	MAP3K8	T558	T558I	558	Missense	central	0	yes	29.457	0.000	PhosphoSitePlus	ICGC;COSMIC	13.250	Loss
STE_STE-Unique_MAP3K8_ST	P06493	CDK1	P41279	MAP3K8	S53	R59H	59	Missense	distal	6	no	16.506	15.201	EPSD	ICGC;COSMIC	13.250	Down-regulation
STE_STE-Unique_MAP3K8_ST	P06493	CDK1	P41279	MAP3K8	S53	R50L	50	Missense	distal	-3	no	16.506	9.377	EPSD	ICGC;COSMIC	13.250	Loss
STE_STE-Unique_MAP3K8_ST	P06493	CDK1	P41279	MAP3K8	S248	H252N	252	Missense	distal	4	no	14.692	15.977	EPSD	ICGC;COSMIC	13.250	Up-regulation
STE_STE-Unique_MAP3K8_ST	P36507	MAP2K2	P41279	MAP3K8	S226	R231C	231	Missense	distal	5	no	29.977	30.695	PhosphoSitePlus;EPSD	ICGC;COSMIC	13.250	Up-regulation
STE_STE-Unique_MAP3K8_ST	O14757	CHEK1	P41279	MAP3K8	S286	V283L	283	Missense	distal	-3	no	16.636	17.292	EPSD	ICGC	13.250	Up-regulation
STE_STE-Unique_MAP3K8_ST	O14757	CHEK1	P41279	MAP3K8	S301	S307Y	307	Missense	distal	6	no	14.872	14.203	EPSD	ICGC;COSMIC	13.250	Down-regulation
STE_STE-Unique_MAP3K8_ST	O14757	CHEK1	P41279	MAP3K8	S307	S307Y	307	Missense	central	0	yes	18.590	0.000	EPSD	ICGC;COSMIC	13.250	Loss
STE_STE-Unique_MAP3K8_ST	O14757	CHEK1	P41279	MAP3K8	S345	L338S	338	Missense	distal	-7	no	22.388	22.446	PhosphoSitePlus	ICGC;COSMIC	13.250	Up-regulation
STE_STE-Unique_MAP3K8_ST	P06748	NPM1	P41279	MAP3K8	S195	R197G	197	Missense	proximal	2	no	31.018	30.328	EPSD	ICGC;COSMIC	13.250	Down-regulation
STE_STE-Unique_MAP3K8_ST	P06748	NPM1	P41279	MAP3K8	S195	P200A	200	Missense	distal	5	no	31.018	31.233	EPSD	ICGC	13.250	Up-regulation
STE_STE-Unique_MAP3K8_ST	P06748	NPM1	P41279	MAP3K8	T199	R197G	197	Missense	proximal	-2	no	36.589	36.042	PhosphoSitePlus	ICGC;COSMIC	13.250	Down-regulation
STE_STE-Unique_MAP3K8_ST	P06748	NPM1	P41279	MAP3K8	T199	A204T	204	Missense	distal	5	no	36.589	36.658	PhosphoSitePlus	ICGC;COSMIC	13.250	Up-regulation
STE_STE-Unique_MAP3K8_ST	P06748	NPM1	P41279	MAP3K8	T199	P200A	200	Missense	proximal	1	no	36.589	33.801	PhosphoSitePlus	ICGC	13.250	Down-regulation
CMGC_MAPK_JNK_MAPK9_ST	P46937	YAP1	P45984	MAPK9	T77	A78T	78	Missense	proximal	1	no	142.599	142.047	EPSD	ICGC;COSMIC	140.458	Down-regulation
CMGC_MAPK_JNK_MAPK9_ST	P46937	YAP1	P45984	MAPK9	T77	V72F	72	Missense	distal	-5	no	142.599	142.670	EPSD	ICGC	140.458	Up-regulation
CMGC_MAPK_JNK_MAPK9_ST	P46937	YAP1	P45984	MAPK9	T110	A117S	117	Missense	distal	7	no	143.596	143.900	EPSD	ICGC	140.458	Up-regulation
CMGC_MAPK_JNK_MAPK9_ST	P46937	YAP1	P45984	MAPK9	T110	A115T	115	Missense	distal	5	no	143.596	143.975	EPSD	ICGC	140.458	Up-regulation
CMGC_MAPK_JNK_MAPK9_ST	P46937	YAP1	P45984	MAPK9	T119	V123F	123	Missense	distal	4	no	163.538	163.892	EPSD;PhosphoSitePlus	ICGC	140.458	Up-regulation
CMGC_MAPK_JNK_MAPK9_ST	P46937	YAP1	P45984	MAPK9	T119	A117S	117	Missense	proximal	-2	no	163.538	161.048	EPSD;PhosphoSitePlus	ICGC	140.458	Down-regulation
CMGC_MAPK_JNK_MAPK9_ST	P46937	YAP1	P45984	MAPK9	T119	A115T	115	Missense	distal	-4	no	163.538	160.913	EPSD;PhosphoSitePlus	ICGC	140.458	Down-regulation
CMGC_MAPK_JNK_MAPK9_ST	P46937	YAP1	P45984	MAPK9	T119	H126R	126	Missense	distal	7	no	163.538	162.941	EPSD;PhosphoSitePlus	ICGC;COSMIC	140.458	Down-regulation
CMGC_MAPK_JNK_MAPK9_ST	P46937	YAP1	P45984	MAPK9	S128	Q133L	133	Missense	distal	5	no	154.316	155.050	EPSD	ICGC;COSMIC	140.458	Up-regulation
CMGC_MAPK_JNK_MAPK9_ST	P46937	YAP1	P45984	MAPK9	S128	V123F	123	Missense	distal	-5	no	154.316	154.387	EPSD	ICGC	140.458	Up-regulation
CMGC_MAPK_JNK_MAPK9_ST	P46937	YAP1	P45984	MAPK9	S128	L134F	134	Missense	distal	6	no	154.316	154.025	EPSD	ICGC;COSMIC	140.458	Down-regulation
CMGC_MAPK_JNK_MAPK9_ST	P46937	YAP1	P45984	MAPK9	S128	H126R	126	Missense	proximal	-2	no	154.316	157.143	EPSD	ICGC;COSMIC	140.458	Up-regulation
CMGC_MAPK_JNK_MAPK9_ST	P46937	YAP1	P45984	MAPK9	S138	Q133L	133	Missense	distal	-5	no	156.939	157.062	EPSD;PhosphoSitePlus	ICGC;COSMIC	140.458	Up-regulation
CMGC_MAPK_JNK_MAPK9_ST	P46937	YAP1	P45984	MAPK9	S138	V137F	137	Missense	proximal	-1	no	156.939	156.709	EPSD;PhosphoSitePlus	ICGC;COSMIC	140.458	Down-regulation
CMGC_MAPK_JNK_MAPK9_ST	P46937	YAP1	P45984	MAPK9	S138	T145N	145	Missense	distal	7	no	156.939	156.468	EPSD;PhosphoSitePlus	ICGC	140.458	Down-regulation
CMGC_MAPK_JNK_MAPK9_ST	P46937	YAP1	P45984	MAPK9	S138	L134F	134	Missense	distal	-4	no	156.939	155.847	EPSD;PhosphoSitePlus	ICGC;COSMIC	140.458	Down-regulation
CMGC_MAPK_JNK_MAPK9_ST	P46937	YAP1	P45984	MAPK9	T143	V137F	137	Missense	distal	-6	no	158.240	157.775	EPSD	ICGC;COSMIC	140.458	Down-regulation
CMGC_MAPK_JNK_MAPK9_ST	P46937	YAP1	P45984	MAPK9	T143	T145N	145	Missense	proximal	2	no	158.240	158.070	EPSD	ICGC	140.458	Down-regulation
CMGC_MAPK_JNK_MAPK9_ST	P46937	YAP1	P45984	MAPK9	T154	R161L	161	Missense	distal	7	no	159.726	160.559	PhosphoSitePlus;EPSD	ICGC	140.458	Up-regulation
CMGC_MAPK_JNK_MAPK9_ST	P46937	YAP1	P45984	MAPK9	S227	G230V	230	Missense	distal	3	no	147.497	147.580	EPSD	ICGC;COSMIC	140.458	Up-regulation
CMGC_MAPK_JNK_MAPK9_ST	P46937	YAP1	P45984	MAPK9	S227	L232H	232	Missense	distal	5	no	147.497	147.305	EPSD	ICGC	140.458	Down-regulation
CMGC_MAPK_JNK_MAPK9_ST	P46937	YAP1	P45984	MAPK9	S336	R331W	331	Missense	distal	-5	no	143.713	143.847	EPSD	ICGC;COSMIC	140.458	Up-regulation
CMGC_MAPK_JNK_MAPK9_ST	P46937	YAP1	P45984	MAPK9	S367	Q372R	372	Missense	distal	5	no	157.971	157.763	EPSD	ICGC;COSMIC	140.458	Down-regulation
CMGC_MAPK_JNK_MAPK9_ST	P46937	YAP1	P45984	MAPK9	S367	G369W	369	Missense	proximal	2	no	157.971	158.121	EPSD	ICGC;COSMIC	140.458	Up-regulation
CMGC_MAPK_JNK_MAPK9_ST	P46937	YAP1	P45984	MAPK9	S367	Q372K	372	Missense	distal	5	no	157.971	158.163	EPSD	ICGC;COSMIC	140.458	Up-regulation
CMGC_MAPK_JNK_MAPK9_ST	P46937	YAP1	P45984	MAPK9	S382	F385S	385	Missense	distal	3	no	141.944	142.297	EPSD	ICGC	140.458	Up-regulation
CMGC_MAPK_JNK_MAPK9_ST	P46937	YAP1	P45984	MAPK9	T412	V409F	409	Missense	distal	-3	no	159.478	157.244	EPSD	ICGC	140.458	Down-regulation
CMGC_MAPK_JNK_MAPK9_ST	P10636	MAPT	P45984	MAPK9	S64	P59Q	59	Missense	distal	-5	no	144.805	144.781	EPSD	ICGC	140.458	Down-regulation
CMGC_MAPK_JNK_MAPK9_ST	P10636	MAPT	P45984	MAPK9	T95	A91T	91	Missense	distal	-4	no	144.342	141.716	EPSD	ICGC;COSMIC	140.458	Down-regulation
CMGC_MAPK_JNK_MAPK9_ST	P10636	MAPT	P45984	MAPK9	T95	P98S	98	Missense	distal	3	no	144.342	144.294	EPSD	ICGC	140.458	Down-regulation
CMGC_MAPK_JNK_MAPK9_ST	P10636	MAPT	P45984	MAPK9	T102	P98S	98	Missense	distal	-4	no	140.567	140.746	EPSD	ICGC	140.458	Up-regulation
CMGC_MAPK_JNK_MAPK9_ST	P10636	MAPT	P45984	MAPK9	T111	D116E	116	Missense	distal	5	no	150.649	150.108	EPSD	ICGC;COSMIC	140.458	Down-regulation
CMGC_MAPK_JNK_MAPK9_ST	P10636	MAPT	P45984	MAPK9	S228	P233H	233	Missense	distal	5	no	156.450	157.026	EPSD	ICGC;COSMIC	140.458	Up-regulation
CMGC_MAPK_JNK_MAPK9_ST	P10636	MAPT	P45984	MAPK9	S228	S232F	232	Missense	distal	4	no	156.450	156.955	EPSD	ICGC	140.458	Up-regulation
CMGC_MAPK_JNK_MAPK9_ST	P10636	MAPT	P45984	MAPK9	S228	D225N	225	Missense	distal	-3	no	156.450	157.702	EPSD	ICGC	140.458	Up-regulation
CMGC_MAPK_JNK_MAPK9_ST	P10636	MAPT	P45984	MAPK9	S228	V224I	224	Missense	distal	-4	no	156.450	155.691	EPSD	ICGC;COSMIC	140.458	Down-regulation
CMGC_MAPK_JNK_MAPK9_ST	P10636	MAPT	P45984	MAPK9	S232	P233H	233	Missense	proximal	1	no	154.055	-6.051	EPSD	ICGC;COSMIC	140.458	Loss
CMGC_MAPK_JNK_MAPK9_ST	P10636	MAPT	P45984	MAPK9	S232	S232F	232	Missense	central	0	yes	154.055	0.000	EPSD	ICGC	140.458	Loss
CMGC_MAPK_JNK_MAPK9_ST	P10636	MAPT	P45984	MAPK9	S232	D225N	225	Missense	distal	-7	no	154.055	156.474	EPSD	ICGC	140.458	Up-regulation
CMGC_MAPK_JNK_MAPK9_ST	P10636	MAPT	P45984	MAPK9	S232	P239Q	239	Missense	distal	7	no	154.055	154.104	EPSD	ICGC;COSMIC	140.458	Up-regulation
CMGC_MAPK_JNK_MAPK9_ST	P10636	MAPT	P45984	MAPK9	S238	P233H	233	Missense	distal	-5	no	155.330	155.378	EPSD	ICGC;COSMIC	140.458	Up-regulation
CMGC_MAPK_JNK_MAPK9_ST	P10636	MAPT	P45984	MAPK9	S238	S232F	232	Missense	distal	-6	no	155.330	154.631	EPSD	ICGC	140.458	Down-regulation
CMGC_MAPK_JNK_MAPK9_ST	P10636	MAPT	P45984	MAPK9	S238	P239Q	239	Missense	proximal	1	no	155.330	135.218	EPSD	ICGC;COSMIC	140.458	Loss
CMGC_MAPK_JNK_MAPK9_ST	P10636	MAPT	P45984	MAPK9	S420	S427F	427	Missense	distal	7	no	139.881	140.677	EPSD	ICGC	140.458	Gain
CMGC_MAPK_JNK_MAPK9_ST	P10636	MAPT	P45984	MAPK9	S428	S427F	427	Missense	proximal	-1	no	156.636	156.261	EPSD	ICGC	140.458	Down-regulation
CMGC_MAPK_JNK_MAPK9_ST	P10636	MAPT	P45984	MAPK9	S438	Y441H	441	Missense	distal	3	no	167.104	167.390	EPSD	ICGC;COSMIC	140.458	Up-regulation
CMGC_MAPK_JNK_MAPK9_ST	P10636	MAPT	P45984	MAPK9	S516	G521R	521	Missense	distal	5	no	152.372	151.563	EPSD	ICGC;COSMIC	140.458	Down-regulation
CMGC_MAPK_JNK_MAPK9_ST	P10636	MAPT	P45984	MAPK9	S519	G521R	521	Missense	proximal	2	no	159.830	159.652	EPSD	ICGC;COSMIC	140.458	Down-regulation
CMGC_MAPK_JNK_MAPK9_ST	P10636	MAPT	P45984	MAPK9	T522	G521R	521	Missense	proximal	-1	no	159.360	159.559	EPSD	ICGC;COSMIC	140.458	Up-regulation
CMGC_MAPK_JNK_MAPK9_ST	P15336	ATF2	P45984	MAPK9	T131	E130K	130	Missense	proximal	-1	no	141.821	141.702	EPSD	ICGC;COSMIC	140.458	Down-regulation
CMGC_MAPK_JNK_MAPK9_ST	P15336	ATF2	P45984	MAPK9	S136	E130K	130	Missense	distal	-6	no	153.807	153.666	EPSD	ICGC;COSMIC	140.458	Down-regulation
CMGC_MAPK_JNK_MAPK9_ST	P15336	ATF2	P45984	MAPK9	T325	S321G	321	Missense	distal	-4	no	157.279	155.745	EPSD	ICGC;COSMIC	140.458	Down-regulation
CMGC_MAPK_JNK_MAPK9_ST	P15336	ATF2	P45984	MAPK9	S328	S321G	321	Missense	distal	-7	no	160.859	160.493	EPSD	ICGC;COSMIC	140.458	Down-regulation
CMGC_MAPK_JNK_MAPK9_ST	P15336	ATF2	P45984	MAPK9	T333	S340L	340	Missense	distal	7	no	152.446	152.857	EPSD	ICGC;COSMIC	140.458	Up-regulation
CMGC_MAPK_JNK_MAPK9_ST	P15336	ATF2	P45984	MAPK9	T333	Q337H	337	Missense	distal	4	no	152.446	152.717	EPSD	ICGC;COSMIC	140.458	Up-regulation
CMGC_MAPK_JNK_MAPK9_ST	P15336	ATF2	P45984	MAPK9	S338	S340L	340	Missense	proximal	2	no	141.803	141.862	EPSD	ICGC;COSMIC	140.458	Up-regulation
CMGC_MAPK_JNK_MAPK9_ST	P15336	ATF2	P45984	MAPK9	S338	Q337H	337	Missense	proximal	-1	no	141.803	141.584	EPSD	ICGC;COSMIC	140.458	Down-regulation
CMGC_MAPK_JNK_MAPK9_ST	P01106	MYC	P45984	MAPK9	S71	P72S	72	Missense	proximal	1	no	158.457	-122.337	PhosphoSitePlus;EPSD	ICGC;COSMIC;GDSC	140.458	Loss
CMGC_MAPK_JNK_MAPK9_ST	P01106	MYC	P45984	MAPK9	S71	P72A	72	Missense	proximal	1	no	158.457	139.813	PhosphoSitePlus;EPSD	ICGC;COSMIC	140.458	Loss
CMGC_MAPK_JNK_MAPK9_ST	P01106	MYC	P45984	MAPK9	S71	P72L	72	Missense	proximal	1	no	158.457	113.554	PhosphoSitePlus;EPSD	ICGC;COSMIC	140.458	Loss
CMGC_MAPK_JNK_MAPK9_ST	P01106	MYC	P45984	MAPK9	S71	P72T	72	Missense	proximal	1	no	158.457	139.261	PhosphoSitePlus;EPSD	ICGC;COSMIC;GDSC	140.458	Loss
CMGC_MAPK_JNK_MAPK9_ST	P01106	MYC	P45984	MAPK9	T78	P72S	72	Missense	distal	-6	no	156.598	156.507	EPSD	ICGC;COSMIC;GDSC	140.458	Down-regulation
CMGC_MAPK_JNK_MAPK9_ST	P01106	MYC	P45984	MAPK9	T78	P72A	72	Missense	distal	-6	no	156.598	156.593	EPSD	ICGC;COSMIC	140.458	Down-regulation
CMGC_MAPK_JNK_MAPK9_ST	P01106	MYC	P45984	MAPK9	T78	P72L	72	Missense	distal	-6	no	156.598	156.156	EPSD	ICGC;COSMIC	140.458	Down-regulation
CMGC_MAPK_JNK_MAPK9_ST	P01106	MYC	P45984	MAPK9	T78	P72T	72	Missense	distal	-6	no	156.598	156.239	EPSD	ICGC;COSMIC;GDSC	140.458	Down-regulation
CMGC_MAPK_JNK_MAPK9_ST	P05067	APP	P45984	MAPK9	T381	E385Q	385	Missense	distal	4	no	152.510	152.489	EPSD	ICGC;COSMIC	140.458	Down-regulation
CMGC_MAPK_JNK_MAPK9_ST	P38936	CDKN1A	P45984	MAPK9	T57	D52N	52	Missense	distal	-5	no	162.997	162.879	EPSD;PhosphoSitePlus	ICGC;COSMIC	140.458	Down-regulation
CMGC_MAPK_JNK_MAPK9_ST	P38936	CDKN1A	P45984	MAPK9	T57	E56D	56	Missense	proximal	-1	no	162.997	162.744	EPSD;PhosphoSitePlus	ICGC	140.458	Down-regulation
CMGC_MAPK_JNK_MAPK9_ST	P38936	CDKN1A	P45984	MAPK9	T57	F51V	51	Missense	distal	-6	no	162.997	163.462	EPSD;PhosphoSitePlus	ICGC;COSMIC	140.458	Up-regulation
CMGC_MAPK_JNK_MAPK9_ST	P38936	CDKN1A	P45984	MAPK9	S130	P131T	131	Missense	proximal	1	no	156.548	137.353	PhosphoSitePlus;EPSD	ICGC;COSMIC	140.458	Loss
CMGC_MAPK_JNK_MAPK9_ST	P38936	CDKN1A	P45984	MAPK9	S130	P131Q	131	Missense	proximal	1	no	156.548	136.436	PhosphoSitePlus;EPSD	ICGC;COSMIC	140.458	Loss
CMGC_MAPK_JNK_MAPK9_ST	P38936	CDKN1A	P45984	MAPK9	S130	G129W	129	Missense	proximal	-1	no	156.548	156.269	PhosphoSitePlus;EPSD	ICGC;COSMIC	140.458	Down-regulation
CMGC_MAPK_JNK_MAPK9_ST	P38936	CDKN1A	P45984	MAPK9	S137	R142Q	142	Missense	distal	5	no	140.385	140.593	EPSD	ICGC	140.458	Gain
CMGC_MAPK_JNK_MAPK9_ST	P19793	RXRA	P45984	MAPK9	S21	T23M	23	Missense	proximal	2	no	156.099	155.911	EPSD	ICGC;COSMIC	140.458	Down-regulation
CMGC_MAPK_JNK_MAPK9_ST	P19793	RXRA	P45984	MAPK9	S49	G42V	42	Missense	distal	-7	no	158.363	157.768	EPSD	ICGC;COSMIC	140.458	Down-regulation
CMGC_MAPK_JNK_MAPK9_ST	P19793	RXRA	P45984	MAPK9	T82	S88I	88	Missense	distal	6	no	155.980	155.722	EPSD	ICGC	140.458	Down-regulation
CMGC_MAPK_JNK_MAPK9_ST	P19793	RXRA	P45984	MAPK9	S222	E221D	221	Missense	proximal	-1	no	142.947	142.694	EPSD	ICGC	140.458	Down-regulation
CMGC_MAPK_JNK_MAPK9_ST	P19793	RXRA	P45984	MAPK9	S222	S224I	224	Missense	proximal	2	no	142.947	142.999	EPSD	ICGC	140.458	Up-regulation
CMGC_MAPK_JNK_MAPK9_ST	P19793	RXRA	P45984	MAPK9	S225	E221D	221	Missense	distal	-4	no	141.453	140.534	EPSD	ICGC	140.458	Down-regulation
CMGC_MAPK_JNK_MAPK9_ST	P19793	RXRA	P45984	MAPK9	S225	S224I	224	Missense	proximal	-1	no	141.453	141.329	EPSD	ICGC	140.458	Down-regulation
CMGC_MAPK_JNK_MAPK9_ST	P19793	RXRA	P45984	MAPK9	S260	P258H	258	Missense	proximal	-2	no	163.067	159.037	PhosphoSitePlus	ICGC;COSMIC	140.458	Down-regulation
CMGC_MAPK_JNK_MAPK9_ST	Q8WYK2	JDP2	P45984	MAPK9	T143	V141I	141	Missense	proximal	-2	no	141.208	142.346	EPSD	ICGC;COSMIC	140.458	Up-regulation
CMGC_MAPK_JNK_MAPK9_ST	Q8WYK2	JDP2	P45984	MAPK9	T143	K147M	147	Missense	distal	4	no	141.208	141.054	EPSD	ICGC;COSMIC	140.458	Down-regulation
CMGC_MAPK_JNK_MAPK9_ST	Q8WYK2	JDP2	P45984	MAPK9	T148	V141I	141	Missense	distal	-7	no	154.686	154.774	PhosphoSitePlus	ICGC;COSMIC	140.458	Up-regulation
CMGC_MAPK_JNK_MAPK9_ST	Q8WYK2	JDP2	P45984	MAPK9	T148	K147M	147	Missense	proximal	-1	no	154.686	154.820	PhosphoSitePlus	ICGC;COSMIC	140.458	Up-regulation
CMGC_MAPK_JNK_MAPK9_ST	P50616	TOB1	P45984	MAPK9	S152	P153S	153	Missense	proximal	1	no	159.585	-121.209	EPSD;PhosphoSitePlus	ICGC;COSMIC	140.458	Loss
CMGC_MAPK_JNK_MAPK9_ST	P50616	TOB1	P45984	MAPK9	S152	H159N	159	Missense	distal	7	no	159.585	159.234	EPSD;PhosphoSitePlus	ICGC	140.458	Down-regulation
CMGC_MAPK_JNK_MAPK9_ST	P50616	TOB1	P45984	MAPK9	S154	P153S	153	Missense	proximal	-1	no	161.569	161.457	PhosphoSitePlus;EPSD	ICGC;COSMIC	140.458	Down-regulation
CMGC_MAPK_JNK_MAPK9_ST	P50616	TOB1	P45984	MAPK9	S154	H159N	159	Missense	distal	5	no	161.569	160.822	PhosphoSitePlus;EPSD	ICGC	140.458	Down-regulation
CMGC_MAPK_JNK_MAPK9_ST	P50616	TOB1	P45984	MAPK9	S164	H159N	159	Missense	distal	-5	no	161.971	161.879	EPSD;PhosphoSitePlus	ICGC	140.458	Down-regulation
CMGC_MAPK_JNK_MAPK9_ST	P50616	TOB1	P45984	MAPK9	S205	V201G	201	Missense	distal	-4	no	155.937	155.505	EPSD	ICGC;COSMIC	140.458	Down-regulation
CMGC_MAPK_JNK_MAPK9_ST	P50616	TOB1	P45984	MAPK9	S205	R203S	203	Missense	proximal	-2	no	155.937	153.379	EPSD	ICGC;COSMIC	140.458	Down-regulation
CMGC_MAPK_JNK_MAPK9_ST	P50616	TOB1	P45984	MAPK9	S268	K263N	263	Missense	distal	-5	no	168.357	168.311	EPSD	ICGC;COSMIC	140.458	Down-regulation
CMGC_MAPK_JNK_MAPK9_ST	Q07817	BCL2L1	P45984	MAPK9	T47	E44D	44	Missense	distal	-3	no	161.645	160.855	PhosphoSitePlus;EPSD	ICGC;COSMIC	140.458	Down-regulation
CMGC_MAPK_JNK_MAPK9_ST	Q07817	BCL2L1	P45984	MAPK9	T47	T47I	47	Missense	central	0	yes	161.645	0.000	PhosphoSitePlus;EPSD	ICGC;COSMIC	140.458	Loss
CMGC_MAPK_JNK_MAPK9_ST	Q07817	BCL2L1	P45984	MAPK9	S62	P63T	63	Missense	proximal	1	no	156.992	137.797	EPSD;PhosphoSitePlus	ICGC	140.458	Loss
CMGC_MAPK_JNK_MAPK9_ST	Q07817	BCL2L1	P45984	MAPK9	T115	S122R	122	Missense	distal	7	no	161.408	160.985	EPSD;PhosphoSitePlus	ICGC	140.458	Down-regulation
CMGC_MAPK_JNK_MAPK9_ST	Q07817	BCL2L1	P45984	MAPK9	T115	T118K	118	Missense	distal	3	no	161.408	161.513	EPSD;PhosphoSitePlus	ICGC	140.458	Up-regulation
CMGC_MAPK_JNK_MAPK9_ST	Q07817	BCL2L1	P45984	MAPK9	T115	T109K	109	Missense	distal	-6	no	161.408	161.691	EPSD;PhosphoSitePlus	ICGC	140.458	Up-regulation
CMGC_MAPK_JNK_MAPK9_ST	Q14934	NFATC4	P45984	MAPK9	S73	R77H	77	Missense	distal	4	no	152.080	152.361	EPSD	ICGC;COSMIC	140.458	Up-regulation
CMGC_MAPK_JNK_MAPK9_ST	Q14934	NFATC4	P45984	MAPK9	S73	P74L	74	Missense	proximal	1	no	152.080	107.178	EPSD	ICGC;COSMIC	140.458	Loss
CMGC_MAPK_JNK_MAPK9_ST	Q14934	NFATC4	P45984	MAPK9	S311	P314L	314	Missense	distal	3	no	163.567	163.259	EPSD	ICGC;COSMIC	140.458	Down-regulation
CMGC_MAPK_JNK_MAPK9_ST	Q14934	NFATC4	P45984	MAPK9	S395	P396S	396	Missense	proximal	1	no	145.228	-135.566	EPSD	ICGC;COSMIC	140.458	Loss
CMGC_MAPK_JNK_MAPK9_ST	Q14934	NFATC4	P45984	MAPK9	S592	V598F	598	Missense	distal	6	no	161.627	161.223	EPSD	ICGC;COSMIC	140.458	Down-regulation
CMGC_MAPK_JNK_MAPK9_ST	Q14934	NFATC4	P45984	MAPK9	S592	V588A	588	Missense	distal	-4	no	161.627	163.283	EPSD	ICGC;COSMIC	140.458	Up-regulation
CMGC_MAPK_JNK_MAPK9_ST	Q14934	NFATC4	P45984	MAPK9	S716	F715C	715	Missense	proximal	-1	no	152.457	152.786	EPSD	ICGC;COSMIC	140.458	Up-regulation
CMGC_MAPK_JNK_MAPK9_ST	Q14934	NFATC4	P45984	MAPK9	S819	P820S	820	Missense	proximal	1	no	163.760	-117.034	EPSD	ICGC;COSMIC	140.458	Loss
CMGC_MAPK_JNK_MAPK9_ST	P52945	PDX1	P45984	MAPK9	S66	E69K	69	Missense	distal	3	no	154.401	154.355	PhosphoSitePlus;EPSD	ICGC	140.458	Down-regulation
CMGC_MAPK_JNK_MAPK9_ST	Q9UGP4	LIMD1	P45984	MAPK9	S211	P212Q	212	Missense	proximal	1	no	151.619	131.507	EPSD	ICGC;COSMIC	140.458	Loss
CMGC_MAPK_JNK_MAPK9_ST	Q9UGP4	LIMD1	P45984	MAPK9	S240	G246A	246	Missense	distal	6	no	141.668	141.980	EPSD	ICGC;COSMIC	140.458	Up-regulation
CMGC_MAPK_JNK_MAPK9_ST	Q9UGP4	LIMD1	P45984	MAPK9	S240	L234M	234	Missense	distal	-6	no	141.668	142.211	EPSD	ICGC;COSMIC	140.458	Up-regulation
CMGC_MAPK_JNK_MAPK9_ST	Q9UGP4	LIMD1	P45984	MAPK9	T294	S296P	296	Missense	proximal	2	no	159.787	159.692	EPSD	ICGC;COSMIC	140.458	Down-regulation
CMGC_MAPK_JNK_MAPK9_ST	Q9UGP4	LIMD1	P45984	MAPK9	T294	A299T	299	Missense	distal	5	no	159.787	160.166	EPSD	ICGC;COSMIC;CCLE	140.458	Up-regulation
CMGC_MAPK_JNK_MAPK9_ST	Q9UGP4	LIMD1	P45984	MAPK9	S298	S296P	296	Missense	proximal	-2	no	142.141	145.902	EPSD	ICGC;COSMIC	140.458	Up-regulation
CMGC_MAPK_JNK_MAPK9_ST	Q9UGP4	LIMD1	P45984	MAPK9	S298	A299T	299	Missense	proximal	1	no	142.141	141.589	EPSD	ICGC;COSMIC;CCLE	140.458	Down-regulation
CMGC_MAPK_JNK_MAPK9_ST	Q9UGP4	LIMD1	P45984	MAPK9	S353	G359R	359	Missense	distal	6	no	153.938	154.151	EPSD	ICGC;COSMIC	140.458	Up-regulation
CMGC_MAPK_JNK_MAPK9_ST	Q9UGP4	LIMD1	P45984	MAPK9	S353	G359C	359	Missense	distal	6	no	153.938	153.977	EPSD	ICGC;COSMIC	140.458	Up-regulation
CMGC_MAPK_JNK_MAPK9_ST	Q9UGP4	LIMD1	P45984	MAPK9	T375	G373D	373	Missense	proximal	-2	no	140.658	140.734	EPSD	ICGC;COSMIC	140.458	Up-regulation
CMGC_MAPK_JNK_MAPK9_ST	Q9UGP4	LIMD1	P45984	MAPK9	S421	R428G	428	Missense	distal	7	no	148.618	149.367	EPSD;PhosphoSitePlus	ICGC	140.458	Up-regulation
CMGC_MAPK_JNK_MAPK9_ST	Q9UGP4	LIMD1	P45984	MAPK9	S421	S416Y	416	Missense	distal	-5	no	148.618	148.767	EPSD;PhosphoSitePlus	ICGC	140.458	Up-regulation
CMGC_MAPK_JNK_MAPK9_ST	Q9UGP4	LIMD1	P45984	MAPK9	S424	R428G	428	Missense	distal	4	no	154.717	155.037	EPSD;PhosphoSitePlus	ICGC	140.458	Up-regulation
CMGC_MAPK_JNK_MAPK9_ST	Q12968	NFATC3	P45984	MAPK9	S163	S169N	169	Missense	distal	6	no	158.558	158.861	EPSD;PhosphoSitePlus	ICGC;COSMIC	140.458	Up-regulation
CMGC_MAPK_JNK_MAPK9_ST	Q12968	NFATC3	P45984	MAPK9	S165	S169N	169	Missense	distal	4	no	161.917	161.884	PhosphoSitePlus;EPSD	ICGC;COSMIC	140.458	Down-regulation
CMGC_MAPK_JNK_MAPK9_ST	Q12968	NFATC3	P45984	MAPK9	S207	R202L	202	Missense	distal	-5	no	152.556	152.664	EPSD	ICGC;COSMIC	140.458	Up-regulation
CMGC_MAPK_JNK_MAPK9_ST	Q12968	NFATC3	P45984	MAPK9	S207	A201P	201	Missense	distal	-6	no	152.556	152.561	EPSD	ICGC;COSMIC	140.458	Up-regulation
CMGC_MAPK_JNK_MAPK9_ST	Q12968	NFATC3	P45984	MAPK9	S236	H233D	233	Missense	distal	-3	no	143.131	144.201	EPSD	ICGC;COSMIC	140.458	Up-regulation
CMGC_MAPK_JNK_MAPK9_ST	Q12968	NFATC3	P45984	MAPK9	S240	H233D	233	Missense	distal	-7	no	154.988	155.621	EPSD	ICGC;COSMIC	140.458	Up-regulation
CMGC_MAPK_JNK_MAPK9_ST	Q12968	NFATC3	P45984	MAPK9	S240	S244Y	244	Missense	distal	4	no	154.988	155.494	EPSD	ICGC;COSMIC	140.458	Up-regulation
CMGC_MAPK_JNK_MAPK9_ST	Q12968	NFATC3	P45984	MAPK9	S244	S244Y	244	Missense	central	0	yes	144.008	0.000	EPSD	ICGC;COSMIC	140.458	Loss
CMGC_MAPK_JNK_MAPK9_ST	Q12968	NFATC3	P45984	MAPK9	S269	P270L	270	Missense	proximal	1	no	162.521	117.618	EPSD	ICGC;COSMIC	140.458	Loss
CMGC_MAPK_JNK_MAPK9_ST	Q12968	NFATC3	P45984	MAPK9	S269	R274W	274	Missense	distal	5	no	162.521	163.872	EPSD	ICGC;COSMIC	140.458	Up-regulation
CMGC_MAPK_JNK_MAPK9_ST	Q12968	NFATC3	P45984	MAPK9	S296	S300F	300	Missense	distal	4	no	155.850	156.355	EPSD	ICGC	140.458	Up-regulation
CMGC_MAPK_JNK_MAPK9_ST	Q12968	NFATC3	P45984	MAPK9	S300	S300F	300	Missense	central	0	yes	147.967	0.000	EPSD	ICGC	140.458	Loss
CMGC_MAPK_JNK_MAPK9_ST	Q12968	NFATC3	P45984	MAPK9	T306	T309M	309	Missense	distal	3	no	141.065	141.240	EPSD	ICGC;COSMIC	140.458	Up-regulation
CMGC_MAPK_JNK_MAPK9_ST	Q12968	NFATC3	P45984	MAPK9	T306	S300F	300	Missense	distal	-6	no	141.065	140.366	EPSD	ICGC	140.458	Loss
CMGC_MAPK_JNK_MAPK9_ST	Q12968	NFATC3	P45984	MAPK9	S366	R369W	369	Missense	distal	3	no	154.406	153.906	EPSD	ICGC;COSMIC;GDSC	140.458	Down-regulation
CMGC_MAPK_JNK_MAPK9_ST	Q12968	NFATC3	P45984	MAPK9	S366	D361N	361	Missense	distal	-5	no	154.406	154.288	EPSD	ICGC	140.458	Down-regulation
CMGC_MAPK_JNK_MAPK9_ST	Q12968	NFATC3	P45984	MAPK9	S366	G363R	363	Missense	distal	-3	no	154.406	156.390	EPSD	ICGC	140.458	Up-regulation
CMGC_MAPK_JNK_MAPK9_ST	Q12968	NFATC3	P45984	MAPK9	T409	R413C	413	Missense	distal	4	no	155.812	156.068	EPSD	ICGC	140.458	Up-regulation
CMGC_MAPK_JNK_MAPK9_ST	Q12968	NFATC3	P45984	MAPK9	T409	R413L	413	Missense	distal	4	no	155.812	156.198	EPSD	ICGC	140.458	Up-regulation
CMGC_MAPK_JNK_MAPK9_ST	Q12968	NFATC3	P45984	MAPK9	T409	H408Y	408	Missense	proximal	-1	no	155.812	155.619	EPSD	ICGC	140.458	Down-regulation
CMGC_MAPK_JNK_MAPK9_ST	Q12968	NFATC3	P45984	MAPK9	S546	R551Q	551	Missense	distal	5	no	144.036	144.244	EPSD	ICGC;COSMIC	140.458	Up-regulation
CMGC_MAPK_JNK_MAPK9_ST	Q12968	NFATC3	P45984	MAPK9	S546	R544L	544	Missense	proximal	-2	no	144.036	144.164	EPSD	ICGC	140.458	Up-regulation
CMGC_MAPK_JNK_MAPK9_ST	Q12968	NFATC3	P45984	MAPK9	S546	R544C	544	Missense	proximal	-2	no	144.036	142.267	EPSD	ICGC;COSMIC	140.458	Down-regulation
CMGC_MAPK_JNK_MAPK9_ST	Q12968	NFATC3	P45984	MAPK9	T698	L701S	701	Missense	distal	3	no	147.737	147.997	EPSD	ICGC	140.458	Up-regulation
CMGC_MAPK_JNK_MAPK9_ST	Q12968	NFATC3	P45984	MAPK9	S1063	S1066P	1066	Missense	distal	3	no	160.786	160.833	EPSD	ICGC;COSMIC	140.458	Up-regulation
CMGC_MAPK_JNK_MAPK9_ST	Q12968	NFATC3	P45984	MAPK9	S1072	R1071I	1071	Missense	proximal	-1	no	141.347	141.086	EPSD	ICGC;COSMIC	140.458	Down-regulation
CMGC_MAPK_JNK_MAPK9_ST	Q12968	NFATC3	P45984	MAPK9	S1072	S1066P	1066	Missense	distal	-6	no	141.347	141.438	EPSD	ICGC;COSMIC	140.458	Up-regulation
CMGC_MAPK_JNK_MAPK9_ST	P05412	JUN	P45984	MAPK9	S63	K70T	70	Missense	distal	7	no	156.619	156.800	EPSD;PhosphoSitePlus	ICGC;COSMIC	140.458	Up-regulation
CMGC_MAPK_JNK_MAPK9_ST	P05412	JUN	P45984	MAPK9	S73	A72E	72	Missense	proximal	-1	no	158.505	158.533	PhosphoSitePlus;EPSD	ICGC;COSMIC	140.458	Up-regulation
CMGC_MAPK_JNK_MAPK9_ST	P05412	JUN	P45984	MAPK9	S73	K70T	70	Missense	distal	-3	no	158.505	158.753	PhosphoSitePlus;EPSD	ICGC;COSMIC	140.458	Up-regulation
CMGC_MAPK_JNK_MAPK9_ST	P05412	JUN	P45984	MAPK9	T91	T93N	93	Missense	proximal	2	no	158.955	158.785	EPSD	ICGC	140.458	Down-regulation
CMGC_MAPK_JNK_MAPK9_ST	P05412	JUN	P45984	MAPK9	T91	L98R	98	Missense	distal	7	no	158.955	158.122	EPSD	ICGC	140.458	Down-regulation
CMGC_MAPK_JNK_MAPK9_ST	P05412	JUN	P45984	MAPK9	T93	T93N	93	Missense	central	0	yes	155.827	0.000	EPSD	ICGC	140.458	Loss
CMGC_MAPK_JNK_MAPK9_ST	P05412	JUN	P45984	MAPK9	T93	L98R	98	Missense	distal	5	no	155.827	154.885	EPSD	ICGC	140.458	Down-regulation
CMGC_MAPK_JNK_MAPK9_ST	P05412	JUN	P45984	MAPK9	T239	T239K	239	Missense	central	0	yes	156.287	0.000	EPSD	ICGC	140.458	Loss
CMGC_MAPK_JNK_MAPK9_ST	P05412	JUN	P45984	MAPK9	S243	T239K	239	Missense	distal	-4	no	157.732	158.901	EPSD	ICGC	140.458	Up-regulation
CMGC_MAPK_JNK_MAPK9_ST	P04637	TP53	P45984	MAPK9	S15	E11K	11	Missense	distal	-4	no	140.584	139.466	EPSD	ICGC;COSMIC	140.458	Loss
CMGC_MAPK_JNK_MAPK9_ST	P04637	TP53	P45984	MAPK9	S20	W23C	23	Missense	distal	3	no	147.780	147.988	EPSD;PhosphoSitePlus	ICGC;COSMIC	140.458	Up-regulation
CMGC_MAPK_JNK_MAPK9_ST	P04637	TP53	P45984	MAPK9	S33	P34L	34	Missense	proximal	1	no	154.719	109.816	EPSD	ICGC;COSMIC	140.458	Loss
CMGC_MAPK_JNK_MAPK9_ST	P04637	TP53	P45984	MAPK9	S33	S33F	33	Missense	central	0	yes	154.719	0.000	EPSD	ICGC;COSMIC	140.458	Loss
CMGC_MAPK_JNK_MAPK9_ST	P04637	TP53	P45984	MAPK9	S33	N30I	30	Missense	distal	-3	no	154.719	152.675	EPSD	ICGC	140.458	Down-regulation
CMGC_MAPK_JNK_MAPK9_ST	P04637	TP53	P45984	MAPK9	S37	P34L	34	Missense	distal	-3	no	140.751	139.178	EPSD	ICGC;COSMIC	140.458	Loss
CMGC_MAPK_JNK_MAPK9_ST	P04637	TP53	P45984	MAPK9	S37	S33F	33	Missense	distal	-4	no	140.751	137.469	EPSD	ICGC;COSMIC	140.458	Loss
CMGC_MAPK_JNK_MAPK9_ST	P04637	TP53	P45984	MAPK9	S37	N30I	30	Missense	distal	-7	no	140.751	137.992	EPSD	ICGC	140.458	Loss
CMGC_MAPK_JNK_MAPK9_ST	P04637	TP53	P45984	MAPK9	S46	D48G	48	Missense	proximal	2	no	158.258	158.265	PhosphoSitePlus;EPSD	ICGC;COSMIC	140.458	Up-regulation
CMGC_MAPK_JNK_MAPK9_ST	P04637	TP53	P45984	MAPK9	S46	Q52K	52	Missense	distal	6	no	158.258	158.012	PhosphoSitePlus;EPSD	ICGC	140.458	Down-regulation
CMGC_MAPK_JNK_MAPK9_ST	P04637	TP53	P45984	MAPK9	T81	A88D	88	Missense	distal	7	no	166.507	167.354	EPSD	ICGC	140.458	Up-regulation
CMGC_MAPK_JNK_MAPK9_ST	P04637	TP53	P45984	MAPK9	T81	P87Q	87	Missense	distal	6	no	166.507	166.739	EPSD	ICGC;COSMIC	140.458	Up-regulation
CMGC_MAPK_JNK_MAPK9_ST	P04637	TP53	P45984	MAPK9	S99	Q100K	100	Missense	proximal	1	no	140.696	-8.107	EPSD	ICGC;COSMIC	140.458	Loss
CMGC_MAPK_JNK_MAPK9_ST	P04637	TP53	P45984	MAPK9	S99	P92T	92	Missense	distal	-7	no	140.696	140.304	EPSD	ICGC;COSMIC	140.458	Loss
CMGC_MAPK_JNK_MAPK9_ST	P04637	TP53	P45984	MAPK9	S99	P92H	92	Missense	distal	-7	no	140.696	140.562	EPSD	ICGC;COSMIC	140.458	Down-regulation
CMGC_MAPK_JNK_MAPK9_ST	P04637	TP53	P45984	MAPK9	S99	G105A	105	Missense	distal	6	no	140.696	141.008	EPSD	ICGC;COSMIC	140.458	Up-regulation
CMGC_MAPK_JNK_MAPK9_ST	P04637	TP53	P45984	MAPK9	S127	T125R	125	Missense	proximal	-2	no	145.026	147.459	EPSD	ICGC;COSMIC	140.458	Up-regulation
CMGC_MAPK_JNK_MAPK9_ST	P04637	TP53	P45984	MAPK9	S127	F134C	134	Missense	distal	7	no	145.026	144.480	EPSD	ICGC;COSMIC;CCLE	140.458	Down-regulation
CMGC_MAPK_JNK_MAPK9_ST	P04637	TP53	P45984	MAPK9	S127	C124G	124	Missense	distal	-3	no	145.026	144.600	EPSD	ICGC;COSMIC	140.458	Down-regulation
CMGC_MAPK_JNK_MAPK9_ST	P04637	TP53	P45984	MAPK9	S127	C124R	124	Missense	distal	-3	no	145.026	146.584	EPSD	ICGC;COSMIC;GDSC;CCLE	140.458	Up-regulation
CMGC_MAPK_JNK_MAPK9_ST	P04637	TP53	P45984	MAPK9	S127	L130H	130	Missense	distal	3	no	145.026	145.172	EPSD	ICGC;COSMIC	140.458	Up-regulation
CMGC_MAPK_JNK_MAPK9_ST	P04637	TP53	P45984	MAPK9	S127	T125A	125	Missense	proximal	-2	no	145.026	147.392	EPSD	ICGC;COSMIC	140.458	Up-regulation
CMGC_MAPK_JNK_MAPK9_ST	P04637	TP53	P45984	MAPK9	S127	K120N	120	Missense	distal	-7	no	145.026	146.462	EPSD	ICGC;COSMIC;GDSC;CCLE	140.458	Up-regulation
CMGC_MAPK_JNK_MAPK9_ST	P04637	TP53	P45984	MAPK9	S127	N131Y	131	Missense	distal	4	no	145.026	145.565	EPSD	ICGC;COSMIC	140.458	Up-regulation
CMGC_MAPK_JNK_MAPK9_ST	P04637	TP53	P45984	MAPK9	S127	K120M	120	Missense	distal	-7	no	145.026	144.931	EPSD	ICGC;COSMIC	140.458	Down-regulation
CMGC_MAPK_JNK_MAPK9_ST	P04637	TP53	P45984	MAPK9	S127	K132M	132	Missense	distal	5	no	145.026	144.776	EPSD	ICGC;COSMIC;CCLE	140.458	Down-regulation
CMGC_MAPK_JNK_MAPK9_ST	P04637	TP53	P45984	MAPK9	S127	M133T	133	Missense	distal	6	no	145.026	144.690	EPSD	ICGC;COSMIC	140.458	Down-regulation
CMGC_MAPK_JNK_MAPK9_ST	P04637	TP53	P45984	MAPK9	S127	K120R	120	Missense	distal	-7	no	145.026	145.156	EPSD	ICGC;COSMIC	140.458	Up-regulation
CMGC_MAPK_JNK_MAPK9_ST	P04637	TP53	P45984	MAPK9	S127	C124Y	124	Missense	distal	-3	no	145.026	142.560	EPSD	ICGC;COSMIC	140.458	Down-regulation
CMGC_MAPK_JNK_MAPK9_ST	P04637	TP53	P45984	MAPK9	T150	R156L	156	Missense	distal	6	no	153.234	152.938	EPSD	ICGC;COSMIC	140.458	Down-regulation
CMGC_MAPK_JNK_MAPK9_ST	P04637	TP53	P45984	MAPK9	T150	L145Q	145	Missense	distal	-5	no	153.234	153.110	EPSD	ICGC;COSMIC	140.458	Down-regulation
CMGC_MAPK_JNK_MAPK9_ST	P04637	TP53	P45984	MAPK9	T150	P152R	152	Missense	proximal	2	no	153.234	153.208	EPSD	ICGC;COSMIC	140.458	Down-regulation
CMGC_MAPK_JNK_MAPK9_ST	P04637	TP53	P45984	MAPK9	T150	G154S	154	Missense	distal	4	no	153.234	153.026	EPSD	ICGC;COSMIC	140.458	Down-regulation
CMGC_MAPK_JNK_MAPK9_ST	P04637	TP53	P45984	MAPK9	T150	V157A	157	Missense	distal	7	no	153.234	152.560	EPSD	ICGC;COSMIC	140.458	Down-regulation
CMGC_MAPK_JNK_MAPK9_ST	P04637	TP53	P45984	MAPK9	T150	P151F	151	Missense	proximal	1	no	153.234	-118.770	EPSD	ICGC;COSMIC	140.458	Loss
CMGC_MAPK_JNK_MAPK9_ST	P04637	TP53	P45984	MAPK9	T150	V147G	147	Missense	distal	-3	no	153.234	153.020	EPSD	ICGC;COSMIC;GDSC;CCLE	140.458	Down-regulation
CMGC_MAPK_JNK_MAPK9_ST	P04637	TP53	P45984	MAPK9	S183	C182W	182	Missense	proximal	-1	no	144.606	144.311	EPSD	ICGC;COSMIC	140.458	Down-regulation
CMGC_MAPK_JNK_MAPK9_ST	P04637	TP53	P45984	MAPK9	S183	H178D	178	Missense	distal	-5	no	144.606	144.632	EPSD	ICGC;COSMIC;CCLE	140.458	Up-regulation
CMGC_MAPK_JNK_MAPK9_ST	P04637	TP53	P45984	MAPK9	S183	D184H	184	Missense	proximal	1	no	144.606	-0.094	EPSD	ICGC;COSMIC	140.458	Loss
CMGC_MAPK_JNK_MAPK9_ST	P04637	TP53	P45984	MAPK9	S183	A189T	189	Missense	distal	6	no	144.606	144.194	EPSD	ICGC;COSMIC	140.458	Down-regulation
CMGC_MAPK_JNK_MAPK9_ST	P04637	TP53	P45984	MAPK9	S183	P190T	190	Missense	distal	7	no	144.606	145.129	EPSD	ICGC;COSMIC	140.458	Up-regulation
CMGC_MAPK_JNK_MAPK9_ST	P04637	TP53	P45984	MAPK9	S183	P190S	190	Missense	distal	7	no	144.606	144.835	EPSD	ICGC;COSMIC	140.458	Up-regulation
CMGC_MAPK_JNK_MAPK9_ST	P04637	TP53	P45984	MAPK9	S183	A189D	189	Missense	distal	6	no	144.606	144.308	EPSD	ICGC;COSMIC	140.458	Down-regulation
CMGC_MAPK_JNK_MAPK9_ST	P04637	TP53	P45984	MAPK9	S183	E180D	180	Missense	distal	-3	no	144.606	143.816	EPSD	ICGC;COSMIC	140.458	Down-regulation
CMGC_MAPK_JNK_MAPK9_ST	P04637	TP53	P45984	MAPK9	S183	C176G	176	Missense	distal	-7	no	144.606	145.514	EPSD	ICGC;COSMIC	140.458	Up-regulation
CMGC_MAPK_JNK_MAPK9_ST	P04637	TP53	P45984	MAPK9	S315	T312I	312	Missense	distal	-3	no	155.450	154.895	EPSD	ICGC;COSMIC	140.458	Down-regulation
CMGC_MAPK_JNK_MAPK9_ST	P04637	TP53	P45984	MAPK9	S315	P322T	322	Missense	distal	7	no	155.450	155.972	EPSD	ICGC	140.458	Up-regulation
CMGC_MAPK_JNK_MAPK9_ST	P04637	TP53	P45984	MAPK9	S376	T377P	377	Missense	proximal	1	no	137.190	156.386	EPSD	ICGC;COSMIC	140.458	Gain
CMGC_MAPK_JNK_MAPK9_ST	Q9UIG0	BAZ1B	P45984	MAPK9	S46	E39G	39	Missense	distal	-7	no	142.052	140.785	EPSD	ICGC	140.458	Down-regulation
CMGC_MAPK_JNK_MAPK9_ST	Q9UIG0	BAZ1B	P45984	MAPK9	S46	R48H	48	Missense	proximal	2	no	142.052	142.235	EPSD	ICGC;COSMIC	140.458	Up-regulation
CMGC_MAPK_JNK_MAPK9_ST	Q9UIG0	BAZ1B	P45984	MAPK9	S46	R41S	41	Missense	distal	-5	no	142.052	142.041	EPSD	ICGC	140.458	Down-regulation
CMGC_MAPK_JNK_MAPK9_ST	Q9UIG0	BAZ1B	P45984	MAPK9	S46	R41H	41	Missense	distal	-5	no	142.052	142.109	EPSD	ICGC;COSMIC	140.458	Up-regulation
CMGC_MAPK_JNK_MAPK9_ST	Q9UIG0	BAZ1B	P45984	MAPK9	S46	T51A	51	Missense	distal	5	no	142.052	141.673	EPSD	ICGC;COSMIC	140.458	Down-regulation
CMGC_MAPK_JNK_MAPK9_ST	Q9UIG0	BAZ1B	P45984	MAPK9	S46	R48P	48	Missense	proximal	2	no	142.052	142.078	EPSD	ICGC;COSMIC	140.458	Up-regulation
CMGC_MAPK_JNK_MAPK9_ST	Q9UIG0	BAZ1B	P45984	MAPK9	S158	G154C	154	Missense	distal	-4	no	159.645	159.908	PhosphoSitePlus	ICGC;COSMIC	140.458	Up-regulation
CMGC_MAPK_JNK_MAPK9_ST	Q9UIG0	BAZ1B	P45984	MAPK9	S158	S161N	161	Missense	distal	3	no	159.645	159.773	PhosphoSitePlus	ICGC;COSMIC	140.458	Up-regulation
CMGC_MAPK_JNK_MAPK9_ST	Q9UIG0	BAZ1B	P45984	MAPK9	S158	N165K	165	Missense	distal	7	no	159.645	159.934	PhosphoSitePlus	ICGC	140.458	Up-regulation
CMGC_MAPK_JNK_MAPK9_ST	Q9UIG0	BAZ1B	P45984	MAPK9	S161	G154C	154	Missense	distal	-7	no	143.487	142.580	EPSD	ICGC;COSMIC	140.458	Down-regulation
CMGC_MAPK_JNK_MAPK9_ST	Q9UIG0	BAZ1B	P45984	MAPK9	S161	S161N	161	Missense	central	0	yes	143.487	0.000	EPSD	ICGC;COSMIC	140.458	Loss
CMGC_MAPK_JNK_MAPK9_ST	Q9UIG0	BAZ1B	P45984	MAPK9	S161	N165K	165	Missense	distal	4	no	143.487	143.536	EPSD	ICGC	140.458	Up-regulation
CMGC_MAPK_JNK_MAPK9_ST	Q9UIG0	BAZ1B	P45984	MAPK9	S197	R193S	193	Missense	distal	-4	no	161.590	161.889	EPSD	ICGC;COSMIC	140.458	Up-regulation
CMGC_MAPK_JNK_MAPK9_ST	Q9UIG0	BAZ1B	P45984	MAPK9	S197	R196T	196	Missense	proximal	-1	no	161.590	161.277	EPSD	ICGC	140.458	Down-regulation
CMGC_MAPK_JNK_MAPK9_ST	Q9UIG0	BAZ1B	P45984	MAPK9	S312	D314E	314	Missense	proximal	2	no	150.992	150.868	EPSD	ICGC	140.458	Down-regulation
CMGC_MAPK_JNK_MAPK9_ST	Q9UIG0	BAZ1B	P45984	MAPK9	S312	P317T	317	Missense	distal	5	no	150.992	151.441	EPSD	ICGC	140.458	Up-regulation
CMGC_MAPK_JNK_MAPK9_ST	Q9UIG0	BAZ1B	P45984	MAPK9	S312	K319N	319	Missense	distal	7	no	150.992	150.703	EPSD	ICGC;COSMIC	140.458	Down-regulation
CMGC_MAPK_JNK_MAPK9_ST	Q9UIG0	BAZ1B	P45984	MAPK9	T323	P317T	317	Missense	distal	-6	no	142.315	141.956	EPSD	ICGC	140.458	Down-regulation
CMGC_MAPK_JNK_MAPK9_ST	Q9UIG0	BAZ1B	P45984	MAPK9	T323	K319N	319	Missense	distal	-4	no	142.315	144.535	EPSD	ICGC;COSMIC	140.458	Up-regulation
CMGC_MAPK_JNK_MAPK9_ST	Q9UIG0	BAZ1B	P45984	MAPK9	S349	S349L	349	Missense	central	0	yes	148.899	0.000	EPSD	ICGC;COSMIC	140.458	Loss
CMGC_MAPK_JNK_MAPK9_ST	Q9UIG0	BAZ1B	P45984	MAPK9	S423	P424S	424	Missense	proximal	1	no	150.878	-129.916	EPSD	ICGC;COSMIC	140.458	Loss
CMGC_MAPK_JNK_MAPK9_ST	Q9UIG0	BAZ1B	P45984	MAPK9	S423	G419W	419	Missense	distal	-4	no	150.878	148.783	EPSD	ICGC;COSMIC	140.458	Down-regulation
CMGC_MAPK_JNK_MAPK9_ST	Q9UIG0	BAZ1B	P45984	MAPK9	T430	P424S	424	Missense	distal	-6	no	156.033	155.942	EPSD	ICGC;COSMIC	140.458	Down-regulation
CMGC_MAPK_JNK_MAPK9_ST	Q9UIG0	BAZ1B	P45984	MAPK9	S699	C695F	695	Missense	distal	-4	no	146.550	144.538	EPSD	ICGC;COSMIC	140.458	Down-regulation
CMGC_MAPK_JNK_MAPK9_ST	Q9UIG0	BAZ1B	P45984	MAPK9	S708	D712G	712	Missense	distal	4	no	145.957	145.879	EPSD	ICGC;COSMIC	140.458	Down-regulation
CMGC_MAPK_JNK_MAPK9_ST	Q9UIG0	BAZ1B	P45984	MAPK9	S716	E720K	720	Missense	distal	4	no	141.426	141.523	EPSD	ICGC;COSMIC	140.458	Up-regulation
CMGC_MAPK_JNK_MAPK9_ST	Q9UIG0	BAZ1B	P45984	MAPK9	S716	D712G	712	Missense	distal	-4	no	141.426	140.595	EPSD	ICGC;COSMIC	140.458	Down-regulation
CMGC_MAPK_JNK_MAPK9_ST	Q9UIG0	BAZ1B	P45984	MAPK9	T983	T982N	982	Missense	proximal	-1	no	157.929	158.277	EPSD	ICGC	140.458	Up-regulation
CMGC_MAPK_JNK_MAPK9_ST	Q9UIG0	BAZ1B	P45984	MAPK9	T983	A978S	978	Missense	distal	-5	no	157.929	157.920	EPSD	ICGC;COSMIC	140.458	Down-regulation
CMGC_MAPK_JNK_MAPK9_ST	Q9UIG0	BAZ1B	P45984	MAPK9	S1147	V1140A	1140	Missense	distal	-7	no	139.792	141.874	EPSD	ICGC;COSMIC	140.458	Gain
CMGC_MAPK_JNK_MAPK9_ST	Q9UIG0	BAZ1B	P45984	MAPK9	S1147	V1145A	1145	Missense	proximal	-2	no	139.792	142.797	EPSD	ICGC	140.458	Gain
CMGC_MAPK_JNK_MAPK9_ST	Q9UIG0	BAZ1B	P45984	MAPK9	S1249	D1253E	1253	Missense	distal	4	no	141.448	141.081	EPSD	ICGC	140.458	Down-regulation
CMGC_MAPK_JNK_MAPK9_ST	Q9UIG0	BAZ1B	P45984	MAPK9	S1251	D1253E	1253	Missense	proximal	2	no	140.733	140.609	EPSD	ICGC	140.458	Down-regulation
CMGC_MAPK_JNK_MAPK9_ST	Q9UIG0	BAZ1B	P45984	MAPK9	S1259	D1253E	1253	Missense	distal	-6	no	141.753	142.316	EPSD	ICGC	140.458	Up-regulation
CMGC_MAPK_JNK_MAPK9_ST	Q9UIG0	BAZ1B	P45984	MAPK9	S1259	E1261K	1261	Missense	proximal	2	no	141.753	141.784	EPSD	ICGC;COSMIC	140.458	Up-regulation
CMGC_MAPK_JNK_MAPK9_ST	Q9UIG0	BAZ1B	P45984	MAPK9	S1259	E1262D	1262	Missense	distal	3	no	141.753	141.605	EPSD	ICGC	140.458	Down-regulation
CMGC_MAPK_JNK_MAPK9_ST	Q9UIG0	BAZ1B	P45984	MAPK9	S1315	H1310N	1310	Missense	distal	-5	no	143.880	143.788	EPSD	ICGC	140.458	Down-regulation
CMGC_MAPK_JNK_MAPK9_ST	Q9UIG0	BAZ1B	P45984	MAPK9	S1315	A1319E	1319	Missense	distal	4	no	143.880	143.872	EPSD	ICGC	140.458	Down-regulation
CMGC_MAPK_JNK_MAPK9_ST	Q9UIG0	BAZ1B	P45984	MAPK9	S1338	R1339Q	1339	Missense	proximal	1	no	123.595	141.071	EPSD	ICGC;GDSC	140.458	Gain
CMGC_MAPK_JNK_MAPK9_ST	P30307	CDC25C	P45984	MAPK9	T48	G55S	55	Missense	distal	7	no	149.860	149.534	EPSD	ICGC;COSMIC	140.458	Down-regulation
CMGC_MAPK_JNK_MAPK9_ST	P30307	CDC25C	P45984	MAPK9	T67	R70C	70	Missense	distal	3	no	149.859	149.566	EPSD	ICGC;COSMIC	140.458	Down-regulation
CMGC_MAPK_JNK_MAPK9_ST	P30307	CDC25C	P45984	MAPK9	S129	R136H	136	Missense	distal	7	no	142.814	143.411	EPSD	ICGC;COSMIC;GDSC	140.458	Up-regulation
CMGC_MAPK_JNK_MAPK9_ST	P30307	CDC25C	P45984	MAPK9	S129	R136S	136	Missense	distal	7	no	142.814	143.236	EPSD	ICGC;COSMIC	140.458	Up-regulation
CMGC_MAPK_JNK_MAPK9_ST	P30307	CDC25C	P45984	MAPK9	T130	R136H	136	Missense	distal	6	no	150.521	150.230	EPSD	ICGC;COSMIC;GDSC	140.458	Down-regulation
CMGC_MAPK_JNK_MAPK9_ST	P30307	CDC25C	P45984	MAPK9	T130	R136S	136	Missense	distal	6	no	150.521	150.484	EPSD	ICGC;COSMIC	140.458	Down-regulation
CMGC_MAPK_JNK_MAPK9_ST	P30307	CDC25C	P45984	MAPK9	S168	T172A	172	Missense	distal	4	no	156.872	156.700	PhosphoSitePlus	ICGC;COSMIC	140.458	Down-regulation
CMGC_MAPK_JNK_MAPK9_ST	P30307	CDC25C	P45984	MAPK9	T171	T172A	172	Missense	proximal	1	no	143.899	144.451	EPSD	ICGC;COSMIC	140.458	Up-regulation
CMGC_MAPK_JNK_MAPK9_ST	P30307	CDC25C	P45984	MAPK9	S214	E219D	219	Missense	distal	5	no	155.121	155.662	EPSD	ICGC;COSMIC	140.458	Up-regulation
CMGC_MAPK_JNK_MAPK9_ST	P31645	SLC6A4	P45984	MAPK9	S52	S52R	52	Missense	central	0	yes	155.179	0.000	EPSD	ICGC;COSMIC	140.458	Loss
CMGC_MAPK_JNK_MAPK9_ST	P31645	SLC6A4	P45984	MAPK9	T67	T67A	67	Missense	central	0	yes	141.478	0.000	EPSD	ICGC;COSMIC	140.458	Loss
CMGC_MAPK_JNK_MAPK9_ST	P31645	SLC6A4	P45984	MAPK9	S559	S559R	559	Missense	central	0	yes	150.586	0.000	EPSD	ICGC	140.458	Loss
CMGC_MAPK_JNK_MAPK9_ST	P31645	SLC6A4	P45984	MAPK9	S559	P561L	561	Missense	proximal	2	no	150.586	150.741	EPSD	ICGC;COSMIC	140.458	Up-regulation
CMGC_MAPK_JNK_MAPK9_ST	P31645	SLC6A4	P45984	MAPK9	S559	S555I	555	Missense	distal	-4	no	150.586	148.725	EPSD	ICGC;GDSC	140.458	Down-regulation
CMGC_MAPK_JNK_MAPK9_ST	P31645	SLC6A4	P45984	MAPK9	S559	P561S	561	Missense	proximal	2	no	150.586	150.681	EPSD	ICGC	140.458	Up-regulation
CMGC_MAPK_JNK_MAPK9_ST	P31645	SLC6A4	P45984	MAPK9	T613	P617Q	617	Missense	distal	4	no	144.631	144.630	EPSD	ICGC	140.458	Down-regulation
CMGC_MAPK_JNK_MAPK9_ST	P31645	SLC6A4	P45984	MAPK9	T616	P617Q	617	Missense	proximal	1	no	150.792	130.680	PhosphoSitePlus	ICGC	140.458	Loss
CMGC_MAPK_JNK_MAPK9_ST	P55957	BID	P45984	MAPK9	T59	Y54H	54	Missense	distal	-5	no	149.467	149.386	PhosphoSitePlus	ICGC;COSMIC	140.458	Down-regulation
CMGC_MAPK_JNK_MAPK9_ST	P55957	BID	P45984	MAPK9	T59	G53D	53	Missense	distal	-6	no	149.467	149.248	PhosphoSitePlus	ICGC;COSMIC	140.458	Down-regulation
CMGC_MAPK_JNK_MAPK9_ST	P55957	BID	P45984	MAPK9	T59	S64C	64	Missense	distal	5	no	149.467	149.854	PhosphoSitePlus	ICGC;COSMIC	140.458	Up-regulation
CMGC_MAPK_JNK_MAPK9_ST	P55957	BID	P45984	MAPK9	T59	D55N	55	Missense	distal	-4	no	149.467	151.488	PhosphoSitePlus	ICGC	140.458	Up-regulation
CMGC_MAPK_JNK_MAPK9_ST	Q8IW41	MAPKAPK5	P45984	MAPK9	S212	Y218C	218	Missense	distal	6	no	161.944	162.288	EPSD	ICGC	140.458	Up-regulation
CMGC_MAPK_JNK_MAPK9_ST	Q8IW41	MAPKAPK5	P45984	MAPK9	S212	G207V	207	Missense	distal	-5	no	161.944	161.948	EPSD	ICGC	140.458	Up-regulation
CMGC_MAPK_JNK_MAPK9_ST	Q8IW41	MAPKAPK5	P45984	MAPK9	T214	Y218C	218	Missense	distal	4	no	156.012	155.650	EPSD	ICGC	140.458	Down-regulation
CMGC_MAPK_JNK_MAPK9_ST	Q8IW41	MAPKAPK5	P45984	MAPK9	T214	G207V	207	Missense	distal	-7	no	156.012	155.417	EPSD	ICGC	140.458	Down-regulation
CMGC_MAPK_JNK_MAPK9_ST	P29966	MARCKS	P45984	MAPK9	S27	G20V	20	Missense	distal	-7	no	160.346	159.752	EPSD	ICGC;COSMIC	140.458	Down-regulation
CMGC_MAPK_JNK_MAPK9_ST	P29966	MARCKS	P45984	MAPK9	S27	G33R	33	Missense	distal	6	no	160.346	160.559	EPSD	ICGC	140.458	Up-regulation
CMGC_MAPK_JNK_MAPK9_ST	P29966	MARCKS	P45984	MAPK9	S63	D68N	68	Missense	distal	5	no	143.236	142.442	EPSD	ICGC;COSMIC	140.458	Down-regulation
CMGC_MAPK_JNK_MAPK9_ST	P29966	MARCKS	P45984	MAPK9	S81	E86K	86	Missense	distal	5	no	160.004	160.148	EPSD	ICGC	140.458	Up-regulation
CMGC_MAPK_JNK_MAPK9_ST	P29966	MARCKS	P45984	MAPK9	S83	E86K	86	Missense	distal	3	no	143.951	143.905	EPSD	ICGC	140.458	Down-regulation
CMGC_MAPK_JNK_MAPK9_ST	P29966	MARCKS	P45984	MAPK9	S118	S118L	118	Missense	central	0	yes	162.494	0.000	EPSD	ICGC;COSMIC	140.458	Loss
CMGC_MAPK_JNK_MAPK9_ST	P29966	MARCKS	P45984	MAPK9	S118	E125G	125	Missense	distal	7	no	162.494	162.958	EPSD	ICGC;COSMIC	140.458	Up-regulation
CMGC_MAPK_JNK_MAPK9_ST	P29966	MARCKS	P45984	MAPK9	T120	S118L	118	Missense	proximal	-2	no	140.766	143.453	EPSD	ICGC;COSMIC	140.458	Up-regulation
CMGC_MAPK_JNK_MAPK9_ST	P29966	MARCKS	P45984	MAPK9	T120	A127T	127	Missense	distal	7	no	140.766	141.364	EPSD	ICGC;COSMIC	140.458	Up-regulation
CMGC_MAPK_JNK_MAPK9_ST	P29966	MARCKS	P45984	MAPK9	T120	E125G	125	Missense	distal	5	no	140.766	141.319	EPSD	ICGC;COSMIC	140.458	Up-regulation
CMGC_MAPK_JNK_MAPK9_ST	P29966	MARCKS	P45984	MAPK9	S128	S132L	132	Missense	distal	4	no	145.975	146.249	EPSD	ICGC;COSMIC	140.458	Up-regulation
CMGC_MAPK_JNK_MAPK9_ST	P29966	MARCKS	P45984	MAPK9	S128	S134T	134	Missense	distal	6	no	145.975	145.699	EPSD	ICGC;COSMIC	140.458	Down-regulation
CMGC_MAPK_JNK_MAPK9_ST	P29966	MARCKS	P45984	MAPK9	S128	A127T	127	Missense	proximal	-1	no	145.975	145.715	EPSD	ICGC;COSMIC	140.458	Down-regulation
CMGC_MAPK_JNK_MAPK9_ST	P29966	MARCKS	P45984	MAPK9	S128	E125G	125	Missense	distal	-3	no	145.975	144.517	EPSD	ICGC;COSMIC	140.458	Down-regulation
CMGC_MAPK_JNK_MAPK9_ST	P29966	MARCKS	P45984	MAPK9	S132	S132L	132	Missense	central	0	yes	145.868	0.000	EPSD	ICGC;COSMIC	140.458	Loss
CMGC_MAPK_JNK_MAPK9_ST	P29966	MARCKS	P45984	MAPK9	S132	S134T	134	Missense	proximal	2	no	145.868	145.949	EPSD	ICGC;COSMIC	140.458	Up-regulation
CMGC_MAPK_JNK_MAPK9_ST	P29966	MARCKS	P45984	MAPK9	S132	A127T	127	Missense	distal	-5	no	145.868	145.905	EPSD	ICGC;COSMIC	140.458	Up-regulation
CMGC_MAPK_JNK_MAPK9_ST	P29966	MARCKS	P45984	MAPK9	S132	E125G	125	Missense	distal	-7	no	145.868	144.600	EPSD	ICGC;COSMIC	140.458	Down-regulation
CMGC_MAPK_JNK_MAPK9_ST	P29966	MARCKS	P45984	MAPK9	T133	S134T	134	Missense	proximal	1	no	-118.574	143.024	EPSD	ICGC;COSMIC	140.458	Gain
CMGC_MAPK_JNK_MAPK9_ST	P29966	MARCKS	P45984	MAPK9	S135	S132L	132	Missense	distal	-3	no	160.014	159.480	EPSD	ICGC;COSMIC	140.458	Down-regulation
CMGC_MAPK_JNK_MAPK9_ST	P29966	MARCKS	P45984	MAPK9	S135	S134T	134	Missense	proximal	-1	no	160.014	159.837	EPSD	ICGC;COSMIC	140.458	Down-regulation
CMGC_MAPK_JNK_MAPK9_ST	P29966	MARCKS	P45984	MAPK9	T143	P144S	144	Missense	proximal	1	no	160.528	-120.266	EPSD	ICGC;COSMIC	140.458	Loss
CMGC_MAPK_JNK_MAPK9_ST	P29966	MARCKS	P45984	MAPK9	S145	P144S	144	Missense	proximal	-1	no	164.178	164.065	EPSD	ICGC;COSMIC	140.458	Down-regulation
CMGC_MAPK_JNK_MAPK9_ST	P29966	MARCKS	P45984	MAPK9	T150	P144S	144	Missense	distal	-6	no	157.787	157.696	EPSD	ICGC;COSMIC	140.458	Down-regulation
CMGC_MAPK_JNK_MAPK9_ST	P29966	MARCKS	P45984	MAPK9	S252	D253N	253	Missense	proximal	1	no	148.517	-36.446	EPSD	ICGC	140.458	Loss
CMGC_MAPK_JNK_MAPK9_ST	P29966	MARCKS	P45984	MAPK9	S308	S314L	314	Missense	distal	6	no	145.391	145.132	EPSD	ICGC;COSMIC	140.458	Down-regulation
CMGC_MAPK_JNK_MAPK9_ST	P29966	MARCKS	P45984	MAPK9	S314	S314L	314	Missense	central	0	yes	145.133	0.000	EPSD	ICGC;COSMIC	140.458	Loss
CMGC_MAPK_JNK_MAPK9_ST	Q15750	TAB1	P45984	MAPK9	T18	P15Q	15	Missense	distal	-3	no	144.934	144.391	EPSD	ICGC;COSMIC	140.458	Down-regulation
CMGC_MAPK_JNK_MAPK9_ST	Q15750	TAB1	P45984	MAPK9	S339	R333Q	333	Missense	distal	-6	no	144.136	144.064	EPSD	ICGC	140.458	Down-regulation
CMGC_MAPK_JNK_MAPK9_ST	Q15750	TAB1	P45984	MAPK9	S339	A343S	343	Missense	distal	4	no	144.136	144.209	EPSD	ICGC	140.458	Up-regulation
CMGC_MAPK_JNK_MAPK9_ST	Q15750	TAB1	P45984	MAPK9	S339	S339I	339	Missense	central	0	yes	144.136	0.000	EPSD	ICGC;COSMIC	140.458	Loss
CMGC_MAPK_JNK_MAPK9_ST	Q15750	TAB1	P45984	MAPK9	T376	S373I	373	Missense	distal	-3	no	144.197	142.808	EPSD	ICGC	140.458	Down-regulation
CMGC_MAPK_JNK_MAPK9_ST	Q15750	TAB1	P45984	MAPK9	T376	P381S	381	Missense	distal	5	no	144.197	144.255	EPSD	ICGC	140.458	Up-regulation
CMGC_MAPK_JNK_MAPK9_ST	Q15750	TAB1	P45984	MAPK9	T376	S378I	378	Missense	proximal	2	no	144.197	144.249	EPSD	ICGC	140.458	Up-regulation
CMGC_MAPK_JNK_MAPK9_ST	Q15750	TAB1	P45984	MAPK9	T376	Q374H	374	Missense	proximal	-2	no	144.197	141.368	EPSD	ICGC;COSMIC	140.458	Down-regulation
CMGC_MAPK_JNK_MAPK9_ST	Q15750	TAB1	P45984	MAPK9	T376	S378R	378	Missense	proximal	2	no	144.197	144.076	EPSD	ICGC;COSMIC	140.458	Down-regulation
CMGC_MAPK_JNK_MAPK9_ST	Q15750	TAB1	P45984	MAPK9	T376	Q374K	374	Missense	proximal	-2	no	144.197	141.527	EPSD	ICGC;COSMIC	140.458	Down-regulation
CMGC_MAPK_JNK_MAPK9_ST	Q15750	TAB1	P45984	MAPK9	S378	S373I	373	Missense	distal	-5	no	146.804	146.898	EPSD	ICGC	140.458	Up-regulation
CMGC_MAPK_JNK_MAPK9_ST	Q15750	TAB1	P45984	MAPK9	S378	P381S	381	Missense	distal	3	no	146.804	146.756	EPSD	ICGC	140.458	Down-regulation
CMGC_MAPK_JNK_MAPK9_ST	Q15750	TAB1	P45984	MAPK9	S378	S378I	378	Missense	central	0	yes	146.804	0.000	EPSD	ICGC	140.458	Loss
CMGC_MAPK_JNK_MAPK9_ST	Q15750	TAB1	P45984	MAPK9	S378	Q374H	374	Missense	distal	-4	no	146.804	143.733	EPSD	ICGC;COSMIC	140.458	Down-regulation
CMGC_MAPK_JNK_MAPK9_ST	Q15750	TAB1	P45984	MAPK9	S378	S378R	378	Missense	central	0	yes	146.804	0.000	EPSD	ICGC;COSMIC	140.458	Loss
CMGC_MAPK_JNK_MAPK9_ST	Q15750	TAB1	P45984	MAPK9	S378	Q374K	374	Missense	distal	-4	no	146.804	144.770	EPSD	ICGC;COSMIC	140.458	Down-regulation
CMGC_MAPK_JNK_MAPK9_ST	Q15750	TAB1	P45984	MAPK9	T431	L434I	434	Missense	distal	3	no	154.477	154.622	EPSD	ICGC;COSMIC	140.458	Up-regulation
CMGC_MAPK_JNK_MAPK9_ST	Q15750	TAB1	P45984	MAPK9	T431	S438R	438	Missense	distal	7	no	154.477	154.054	EPSD	ICGC;COSMIC	140.458	Down-regulation
CMGC_MAPK_JNK_MAPK9_ST	Q15750	TAB1	P45984	MAPK9	S438	L434I	434	Missense	distal	-4	no	155.886	156.216	PhosphoSitePlus	ICGC;COSMIC	140.458	Up-regulation
CMGC_MAPK_JNK_MAPK9_ST	Q15750	TAB1	P45984	MAPK9	S438	S438R	438	Missense	central	0	yes	155.886	0.000	PhosphoSitePlus	ICGC;COSMIC	140.458	Loss
CMGC_MAPK_JNK_MAPK9_ST	Q9UQF2	MAPK8IP1	P45984	MAPK9	S15	S15N	15	Missense	central	0	yes	155.179	0.000	EPSD	ICGC;COSMIC	140.458	Loss
CMGC_MAPK_JNK_MAPK9_ST	Q9UQF2	MAPK8IP1	P45984	MAPK9	S15	G8V	8	Missense	distal	-7	no	155.179	154.584	EPSD	ICGC	140.458	Down-regulation
CMGC_MAPK_JNK_MAPK9_ST	Q9UQF2	MAPK8IP1	P45984	MAPK9	S15	P21R	21	Missense	distal	6	no	155.179	155.242	EPSD	ICGC;COSMIC	140.458	Up-regulation
CMGC_MAPK_JNK_MAPK9_ST	Q9UQF2	MAPK8IP1	P45984	MAPK9	S15	P17L	17	Missense	proximal	2	no	155.179	155.334	EPSD	ICGC;COSMIC	140.458	Up-regulation
CMGC_MAPK_JNK_MAPK9_ST	Q9UQF2	MAPK8IP1	P45984	MAPK9	S15	A18T	18	Missense	distal	3	no	155.179	154.968	EPSD	ICGC;COSMIC	140.458	Down-regulation
CMGC_MAPK_JNK_MAPK9_ST	Q9UQF2	MAPK8IP1	P45984	MAPK9	S20	S15N	15	Missense	distal	-5	no	161.699	161.675	EPSD	ICGC;COSMIC	140.458	Down-regulation
CMGC_MAPK_JNK_MAPK9_ST	Q9UQF2	MAPK8IP1	P45984	MAPK9	S20	P21R	21	Missense	proximal	1	no	161.699	124.111	EPSD	ICGC;COSMIC	140.458	Loss
CMGC_MAPK_JNK_MAPK9_ST	Q9UQF2	MAPK8IP1	P45984	MAPK9	S20	P17L	17	Missense	distal	-3	no	161.699	160.126	EPSD	ICGC;COSMIC	140.458	Down-regulation
CMGC_MAPK_JNK_MAPK9_ST	Q9UQF2	MAPK8IP1	P45984	MAPK9	S20	A18T	18	Missense	proximal	-2	no	161.699	159.333	EPSD	ICGC;COSMIC	140.458	Down-regulation
CMGC_MAPK_JNK_MAPK9_ST	Q9UQF2	MAPK8IP1	P45984	MAPK9	S311	P315L	315	Missense	distal	4	no	141.853	142.229	EPSD	ICGC;COSMIC	140.458	Up-regulation
CMGC_MAPK_JNK_MAPK9_ST	Q9UQF2	MAPK8IP1	P45984	MAPK9	S311	P315T	315	Missense	distal	4	no	141.853	142.052	EPSD	ICGC;COSMIC	140.458	Up-regulation
CMGC_MAPK_JNK_MAPK9_ST	P98177	FOXO4	P45984	MAPK9	S241	P242L	242	Missense	proximal	1	no	154.833	109.931	EPSD	ICGC;COSMIC	140.458	Loss
CMGC_MAPK_JNK_MAPK9_ST	Q9NYV6	RRN3	P45984	MAPK9	S170	V169F	169	Missense	proximal	-1	no	144.726	144.496	EPSD	ICGC;COSMIC	140.458	Down-regulation
CMGC_MAPK_JNK_MAPK9_ST	Q9NYV6	RRN3	P45984	MAPK9	T200	S199L	199	Missense	proximal	-1	no	157.330	157.286	PhosphoSitePlus	ICGC;COSMIC	140.458	Down-regulation
CMGC_MAPK_JNK_MAPK9_ST	Q9NYV6	RRN3	P45984	MAPK9	T200	P201S	201	Missense	proximal	1	no	157.330	-123.464	PhosphoSitePlus	ICGC;COSMIC	140.458	Loss
CMGC_MAPK_JNK_MAPK9_ST	Q9BQQ3	GORASP1	P45984	MAPK9	S274	A279D	279	Missense	distal	5	no	160.623	161.176	PhosphoSitePlus	ICGC	140.458	Up-regulation
AGC_NDR_LATS_LATS2_ST	Q9NQS7	INCENP	Q9NRM7	LATS2	S72	R66W	66	Missense	distal	-6	no	0.048	0.049	EPSD	ICGC;COSMIC	0.004	Up-regulation
AGC_NDR_LATS_LATS2_ST	Q9NQS7	INCENP	Q9NRM7	LATS2	S72	R66Q	66	Missense	distal	-6	no	0.048	0.049	EPSD	ICGC;COSMIC	0.004	Up-regulation
AGC_NDR_LATS_LATS2_ST	Q9NQS7	INCENP	Q9NRM7	LATS2	S103	R100C	100	Missense	distal	-3	no	0.056	0.008	EPSD	ICGC;COSMIC	0.004	Down-regulation
AGC_NDR_LATS_LATS2_ST	Q9NQS7	INCENP	Q9NRM7	LATS2	S255	V248G	248	Missense	distal	-7	no	0.050	0.051	EPSD	ICGC;COSMIC	0.004	Up-regulation
AGC_NDR_LATS_LATS2_ST	Q9NQS7	INCENP	Q9NRM7	LATS2	S336	A340S	340	Missense	distal	4	no	0.047	0.048	EPSD	ICGC;COSMIC	0.004	Up-regulation
AGC_NDR_LATS_LATS2_ST	Q9NQS7	INCENP	Q9NRM7	LATS2	S336	R338M	338	Missense	proximal	2	no	0.047	0.049	EPSD	ICGC	0.004	Up-regulation
AGC_NDR_LATS_LATS2_ST	Q9NQS7	INCENP	Q9NRM7	LATS2	S357	R352H	352	Missense	distal	-5	no	-0.002	0.010	EPSD	ICGC;GDSC;CCLE	0.004	Gain
AGC_NDR_LATS_LATS2_ST	Q9NQS7	INCENP	Q9NRM7	LATS2	S400	G397R	397	Missense	distal	-3	no	-0.002	0.050	EPSD	ICGC	0.004	Gain
AGC_NDR_LATS_LATS2_ST	Q9NQS7	INCENP	Q9NRM7	LATS2	S518	R513H	513	Missense	distal	-5	no	-0.003	0.009	EPSD	ICGC;GDSC;CCLE	0.004	Gain
AGC_NDR_LATS_LATS2_ST	Q9NQS7	INCENP	Q9NRM7	LATS2	S909	S914R	914	Missense	distal	5	no	0.046	0.045	EPSD	ICGC;COSMIC	0.004	Down-regulation
AGC_NDR_LATS_LATS2_ST	P38936	CDKN1A	Q9NRM7	LATS2	T145	R142Q	142	Missense	distal	-3	no	0.041	-0.008	EPSD	ICGC	0.004	Loss
AGC_NDR_LATS_LATS2_ST	P38936	CDKN1A	Q9NRM7	LATS2	T145	R140Q	140	Missense	distal	-5	no	0.041	0.042	EPSD	ICGC;COSMIC	0.004	Up-regulation
AGC_NDR_LATS_LATS2_ST	P38936	CDKN1A	Q9NRM7	LATS2	S146	R143L	143	Missense	distal	-3	no	0.054	0.004	PhosphoSitePlus	ICGC	0.004	Down-regulation
AGC_NDR_LATS_LATS2_ST	P38936	CDKN1A	Q9NRM7	LATS2	S146	R142Q	142	Missense	distal	-4	no	0.054	0.053	PhosphoSitePlus	ICGC	0.004	Down-regulation
AGC_NDR_LATS_LATS2_ST	P00519	ABL1	Q9NRM7	LATS2	S50	R47C	47	Missense	distal	-3	no	0.050	0.003	EPSD	ICGC;COSMIC	0.004	Loss
AGC_NDR_LATS_LATS2_ST	P00519	ABL1	Q9NRM7	LATS2	S75	Y70H	70	Missense	distal	-5	no	0.000	0.011	EPSD	ICGC;COSMIC	0.004	Gain
AGC_NDR_LATS_LATS2_ST	P00519	ABL1	Q9NRM7	LATS2	S81	G85C	85	Missense	distal	4	no	0.004	0.003	EPSD	ICGC;COSMIC	0.004	Loss
AGC_NDR_LATS_LATS2_ST	P00519	ABL1	Q9NRM7	LATS2	S164	G169W	169	Missense	distal	5	no	0.042	0.043	EPSD	ICGC;COSMIC	0.004	Up-regulation
AGC_NDR_LATS_LATS2_ST	P00519	ABL1	Q9NRM7	LATS2	S164	S164L	164	Missense	central	0	yes	0.042	0.000	EPSD	ICGC;CCLE	0.004	Loss
AGC_NDR_LATS_LATS2_ST	P00519	ABL1	Q9NRM7	LATS2	S164	R170G	170	Missense	distal	6	no	0.042	0.043	EPSD	ICGC;COSMIC	0.004	Up-regulation
AGC_NDR_LATS_LATS2_ST	P00519	ABL1	Q9NRM7	LATS2	S164	R161M	161	Missense	distal	-3	no	0.042	-0.007	EPSD	ICGC;COSMIC	0.004	Loss
AGC_NDR_LATS_LATS2_ST	P00519	ABL1	Q9NRM7	LATS2	S187	E189G	189	Missense	proximal	2	no	0.003	0.004	EPSD	ICGC;COSMIC	0.004	Gain
AGC_NDR_LATS_LATS2_ST	P00519	ABL1	Q9NRM7	LATS2	T306	G303R	303	Missense	distal	-3	no	-0.003	0.048	EPSD	ICGC;COSMIC	0.004	Gain
AGC_NDR_LATS_LATS2_ST	P00519	ABL1	Q9NRM7	LATS2	T597	S601G	601	Missense	distal	4	no	0.003	0.004	EPSD	ICGC;COSMIC	0.004	Gain
AGC_NDR_LATS_LATS2_ST	P00519	ABL1	Q9NRM7	LATS2	S601	K607N	607	Missense	distal	6	no	0.004	0.005	EPSD	ICGC;COSMIC	0.004	Up-regulation
AGC_NDR_LATS_LATS2_ST	P00519	ABL1	Q9NRM7	LATS2	S601	L599F	599	Missense	proximal	-2	no	0.004	0.005	EPSD	ICGC	0.004	Up-regulation
AGC_NDR_LATS_LATS2_ST	P00519	ABL1	Q9NRM7	LATS2	S601	S601G	601	Missense	central	0	yes	0.004	0.000	EPSD	ICGC;COSMIC	0.004	Loss
AGC_NDR_LATS_LATS2_ST	P00519	ABL1	Q9NRM7	LATS2	S601	S601R	601	Missense	central	0	yes	0.004	0.000	EPSD	ICGC;COSMIC	0.004	Loss
AGC_NDR_LATS_LATS2_ST	P00519	ABL1	Q9NRM7	LATS2	S620	R617C	617	Missense	distal	-3	no	0.046	-0.002	EPSD	ICGC;COSMIC	0.004	Loss
AGC_NDR_LATS_LATS2_ST	P00519	ABL1	Q9NRM7	LATS2	S620	R617H	617	Missense	distal	-3	no	0.046	-0.004	EPSD	ICGC;COSMIC	0.004	Loss
AGC_NDR_LATS_LATS2_ST	P00519	ABL1	Q9NRM7	LATS2	S642	S642G	642	Missense	central	0	yes	0.051	0.000	EPSD	ICGC	0.004	Loss
AGC_NDR_LATS_LATS2_ST	P00519	ABL1	Q9NRM7	LATS2	S690	H685R	685	Missense	distal	-5	no	0.007	-0.005	EPSD	ICGC;COSMIC	0.004	Loss
AGC_NDR_LATS_LATS2_ST	P00519	ABL1	Q9NRM7	LATS2	T700	G706S	706	Missense	distal	6	no	0.050	0.051	EPSD	ICGC;COSMIC	0.004	Up-regulation
AGC_NDR_LATS_LATS2_ST	P00519	ABL1	Q9NRM7	LATS2	S716	R712H	712	Missense	distal	-4	no	0.006	0.005	EPSD	ICGC;COSMIC	0.004	Down-regulation
AGC_NDR_LATS_LATS2_ST	P00519	ABL1	Q9NRM7	LATS2	S716	K711N	711	Missense	distal	-5	no	0.006	0.004	EPSD	ICGC;COSMIC	0.004	Down-regulation
AGC_NDR_LATS_LATS2_ST	P00519	ABL1	Q9NRM7	LATS2	S718	R715H	715	Missense	distal	-3	no	0.049	-0.001	EPSD	ICGC;COSMIC	0.004	Loss
AGC_NDR_LATS_LATS2_ST	P00519	ABL1	Q9NRM7	LATS2	S718	R715C	715	Missense	distal	-3	no	0.049	0.001	EPSD	ICGC;CCLE	0.004	Loss
AGC_NDR_LATS_LATS2_ST	P00519	ABL1	Q9NRM7	LATS2	S720	R715H	715	Missense	distal	-5	no	0.000	0.012	EPSD	ICGC;COSMIC	0.004	Gain
AGC_NDR_LATS_LATS2_ST	P00519	ABL1	Q9NRM7	LATS2	T735	D728Y	728	Missense	distal	-7	no	0.047	0.048	EPSD	ICGC	0.004	Up-regulation
AGC_NDR_LATS_LATS2_ST	P00519	ABL1	Q9NRM7	LATS2	T844	A841V	841	Missense	distal	-3	no	0.005	0.006	EPSD	ICGC;COSMIC	0.004	Up-regulation
AGC_NDR_LATS_LATS2_ST	Q8NHZ8	CDC26	Q9NRM7	LATS2	S56	S51R	51	Missense	distal	-5	no	0.004	0.003	EPSD	ICGC;COSMIC	0.004	Loss
AGC_NDR_LATS_LATS2_ST	P46937	YAP1	Q9NRM7	LATS2	S131	Q133L	133	Missense	proximal	2	no	0.011	0.012	EPSD	ICGC;COSMIC	0.004	Up-regulation
AGC_NDR_LATS_LATS2_ST	P46937	YAP1	Q9NRM7	LATS2	S131	H126R	126	Missense	distal	-5	no	0.011	-0.001	EPSD	ICGC;COSMIC	0.004	Loss
AGC_NDR_LATS_LATS2_ST	P46937	YAP1	Q9NRM7	LATS2	S164	R161L	161	Missense	distal	-3	no	0.064	0.014	EPSD;PhosphoSitePlus	ICGC	0.004	Down-regulation
AGC_NDR_LATS_LATS2_ST	P46937	YAP1	Q9NRM7	LATS2	S164	S164F	164	Missense	central	0	yes	0.064	0.000	EPSD;PhosphoSitePlus	ICGC	0.004	Loss
AGC_NDR_LATS_LATS2_ST	P46937	YAP1	Q9NRM7	LATS2	S397	R394Q	394	Missense	distal	-3	no	0.061	0.013	EPSD	ICGC;COSMIC	0.004	Down-regulation
AGC_NDR_LATS_LATS2_ST	P46937	YAP1	Q9NRM7	LATS2	S397	S397I	397	Missense	central	0	yes	0.061	0.000	EPSD	ICGC	0.004	Loss
AGC_NDR_LATS_LATS2_ST	P46937	YAP1	Q9NRM7	LATS2	S397	H392N	392	Missense	distal	-5	no	0.061	0.051	EPSD	ICGC;COSMIC	0.004	Down-regulation
AGC_NDR_LATS_LATS2_ST	P46937	YAP1	Q9NRM7	LATS2	T425	E422K	422	Missense	distal	-3	no	0.003	0.004	EPSD	ICGC;COSMIC	0.004	Gain
AGC_NDR_LATS_LATS2_ST	Q9Y2J4	AMOTL2	Q9NRM7	LATS2	S157	S157L	157	Missense	central	0	yes	0.014	0.000	EPSD	ICGC;COSMIC	0.004	Loss
AGC_NDR_LATS_LATS2_ST	Q9Y2J4	AMOTL2	Q9NRM7	LATS2	S176	G171S	171	Missense	distal	-5	no	0.051	0.050	EPSD	ICGC	0.004	Down-regulation
AGC_NDR_LATS_LATS2_ST	Q9Y2J4	AMOTL2	Q9NRM7	LATS2	S176	S176G	176	Missense	central	0	yes	0.051	0.000	EPSD	ICGC;COSMIC	0.004	Loss
AGC_NDR_LATS_LATS2_ST	Q9Y2J4	AMOTL2	Q9NRM7	LATS2	S180	P175H	175	Missense	distal	-5	no	-0.004	0.007	EPSD	ICGC;COSMIC	0.004	Gain
AGC_NDR_LATS_LATS2_ST	Q9Y2J4	AMOTL2	Q9NRM7	LATS2	T512	R509H	509	Missense	distal	-3	no	0.050	0.000	EPSD	ICGC;COSMIC	0.004	Loss
AGC_NDR_LATS_LATS2_ST	Q9Y2J4	AMOTL2	Q9NRM7	LATS2	S723	H718N	718	Missense	distal	-5	no	0.010	0.000	EPSD	ICGC	0.004	Loss
AGC_NDR_LATS_LATS2_ST	P61981	YWHAG	Q9NRM7	LATS2	S59	R56H	56	Missense	distal	-3	no	0.052	0.003	PhosphoSitePlus	ICGC;COSMIC	0.004	Loss
AGC_NDR_LATS_LATS2_ST	P61981	YWHAG	Q9NRM7	LATS2	S59	S59F	59	Missense	central	0	yes	0.052	0.000	PhosphoSitePlus	ICGC	0.004	Loss
AGC_NDR_LATS_LATS2_ST	P61981	YWHAG	Q9NRM7	LATS2	T139	L134V	134	Missense	distal	-5	no	0.004	0.003	EPSD	ICGC;COSMIC	0.004	Loss
AGC_NDR_LATS_LATS2_ST	Q4VCS5	AMOT	Q9NRM7	LATS2	S175	R177P	177	Missense	proximal	2	no	0.060	0.061	PhosphoSitePlus	ICGC;COSMIC	0.004	Up-regulation
AGC_NDR_LATS_LATS2_ST	Q4VCS5	AMOT	Q9NRM7	LATS2	S196	A197T	197	Missense	proximal	1	no	0.007	0.008	EPSD	ICGC;COSMIC	0.004	Up-regulation
AGC_NDR_LATS_LATS2_ST	Q4VCS5	AMOT	Q9NRM7	LATS2	T709	R706S	706	Missense	distal	-3	no	0.047	-0.006	EPSD	ICGC;COSMIC	0.004	Loss
AGC_NDR_LATS_LATS2_ST	Q4VCS5	AMOT	Q9NRM7	LATS2	S718	N716K	716	Missense	proximal	-2	no	0.009	0.010	EPSD	ICGC;COSMIC	0.004	Up-regulation
AGC_NDR_LATS_LATS2_ST	Q4VCS5	AMOT	Q9NRM7	LATS2	S863	R868C	868	Missense	distal	5	no	0.046	0.047	EPSD	ICGC;COSMIC	0.004	Up-regulation
AGC_NDR_LATS_LATS2_ST	Q9GZV5	WWTR1	Q9NRM7	LATS2	S87	A82V	82	Missense	distal	-5	no	0.005	0.006	EPSD	ICGC;COSMIC	0.004	Up-regulation
AGC_NDR_LATS_LATS2_ST	Q9GZV5	WWTR1	Q9NRM7	LATS2	S174	P176T	176	Missense	proximal	2	no	0.009	0.008	EPSD	ICGC	0.004	Down-regulation
AGC_NDR_LATS_LATS2_ST	Q9GZV5	WWTR1	Q9NRM7	LATS2	T292	T292P	292	Missense	central	0	yes	0.048	0.000	EPSD	ICGC	0.004	Loss
AGC_NDR_LATS_LATS2_ST	O95863	SNAI1	Q9NRM7	LATS2	S246	R243W	243	Missense	distal	-3	no	0.049	0.002	EPSD	ICGC;COSMIC	0.004	Loss
Other_CAMKK_CAMKK-Meta_CAMKK2_ST	Q96EB6	SIRT1	Q96RR4	CAMKK2	S27	S27F	27	Missense	central	0	yes	33.029	0.000	EPSD;PhosphoSitePlus	ICGC;COSMIC	15.642	Loss
Other_CAMKK_CAMKK-Meta_CAMKK2_ST	Q96EB6	SIRT1	Q96RR4	CAMKK2	S27	P28S	28	Missense	proximal	1	no	33.029	33.139	EPSD;PhosphoSitePlus	ICGC;COSMIC	15.642	Up-regulation
Other_CAMKK_CAMKK-Meta_CAMKK2_ST	Q96EB6	SIRT1	Q96RR4	CAMKK2	S27	S27P	27	Missense	central	0	yes	33.029	0.000	EPSD;PhosphoSitePlus	ICGC	15.642	Loss
Other_CAMKK_CAMKK-Meta_CAMKK2_ST	Q96RR4	CAMKK2	Q96RR4	CAMKK2	T85	P92H	92	Missense	distal	7	no	34.513	34.298	PhosphoSitePlus	ICGC;COSMIC	15.642	Down-regulation
Other_CAMKK_CAMKK-Meta_CAMKK2_ST	Q96RR4	CAMKK2	Q96RR4	CAMKK2	T85	P92L	92	Missense	distal	7	no	34.513	34.197	PhosphoSitePlus	ICGC	15.642	Down-regulation
Other_CAMKK_CAMKK-Meta_CAMKK2_ST	Q96RR4	CAMKK2	Q96RR4	CAMKK2	S129	Y128C	128	Missense	proximal	-1	no	18.509	18.417	EPSD	ICGC;COSMIC	15.642	Down-regulation
Other_CAMKK_CAMKK-Meta_CAMKK2_ST	Q96RR4	CAMKK2	Q96RR4	CAMKK2	S129	S136F	136	Missense	distal	7	no	18.509	18.303	EPSD	ICGC	15.642	Down-regulation
Other_CAMKK_CAMKK-Meta_CAMKK2_ST	Q96RR4	CAMKK2	Q96RR4	CAMKK2	S132	Y128C	128	Missense	distal	-4	no	20.166	20.162	EPSD	ICGC;COSMIC	15.642	Down-regulation
Other_CAMKK_CAMKK-Meta_CAMKK2_ST	Q96RR4	CAMKK2	Q96RR4	CAMKK2	S132	S136F	136	Missense	distal	4	no	20.166	17.573	EPSD	ICGC	15.642	Down-regulation
Other_CAMKK_CAMKK-Meta_CAMKK2_ST	Q96RR4	CAMKK2	Q96RR4	CAMKK2	T350	T347S	347	Missense	distal	-3	no	18.401	18.396	EPSD	ICGC;COSMIC	15.642	Down-regulation
Other_CAMKK_CAMKK-Meta_CAMKK2_ST	Q96RR4	CAMKK2	Q96RR4	CAMKK2	T350	F353L	353	Missense	distal	3	no	18.401	16.993	EPSD	ICGC	15.642	Down-regulation
Other_CAMKK_CAMKK-Meta_CAMKK2_ST	Q96RR4	CAMKK2	Q96RR4	CAMKK2	T350	T347N	347	Missense	distal	-3	no	18.401	18.426	EPSD	ICGC	15.642	Up-regulation
Other_CAMKK_CAMKK-Meta_CAMKK2_ST	Q96RR4	CAMKK2	Q96RR4	CAMKK2	T350	A352T	352	Missense	proximal	2	no	18.401	17.381	EPSD	ICGC	15.642	Down-regulation
Other_CAMKK_CAMKK-Meta_CAMKK2_ST	Q96RR4	CAMKK2	Q96RR4	CAMKK2	S511	T518N	518	Missense	distal	7	no	15.890	15.718	EPSD	ICGC	15.642	Down-regulation
Other_CAMKK_CAMKK-Meta_CAMKK2_ST	Q96RR4	CAMKK2	Q96RR4	CAMKK2	S511	R508H	508	Missense	distal	-3	no	15.890	15.892	EPSD	ICGC	15.642	Up-regulation
Other_CAMKK_CAMKK-Meta_CAMKK2_ST	Q13131	PRKAA1	Q96RR4	CAMKK2	T183	N189S	189	Missense	distal	6	no	44.895	44.804	PhosphoSitePlus	ICGC;COSMIC;CCLE	15.642	Down-regulation
Other_CAMKK_CAMKK-Meta_CAMKK2_ST	Q13131	PRKAA1	Q96RR4	CAMKK2	T183	T183K	183	Missense	central	0	yes	44.895	0.000	PhosphoSitePlus	ICGC	15.642	Loss
Other_CAMKK_CAMKK-Meta_CAMKK2_ST	Q13131	PRKAA1	Q96RR4	CAMKK2	S184	N189S	189	Missense	distal	5	no	16.153	24.498	EPSD	ICGC;COSMIC;CCLE	15.642	Up-regulation
Other_CAMKK_CAMKK-Meta_CAMKK2_ST	Q13131	PRKAA1	Q96RR4	CAMKK2	S184	T183K	183	Missense	proximal	-1	no	16.153	16.050	EPSD	ICGC	15.642	Down-regulation
Other_CAMKK_CAMKK-Meta_CAMKK2_ST	Q13131	PRKAA1	Q96RR4	CAMKK2	T355	L362I	362	Missense	distal	7	no	15.719	15.777	EPSD	ICGC;COSMIC	15.642	Up-regulation
Other_CAMKK_CAMKK-Meta_CAMKK2_ST	Q13131	PRKAA1	Q96RR4	CAMKK2	T355	A354V	354	Missense	proximal	-1	no	15.719	15.290	EPSD	ICGC;COSMIC	15.642	Loss
Other_CAMKK_CAMKK-Meta_CAMKK2_ST	Q13131	PRKAA1	Q96RR4	CAMKK2	T355	S360F	360	Missense	distal	5	no	15.719	9.929	EPSD	ICGC	15.642	Loss
Other_CAMKK_CAMKK-Meta_CAMKK2_ST	Q13131	PRKAA1	Q96RR4	CAMKK2	T355	D350Y	350	Missense	distal	-5	no	15.719	15.391	EPSD	ICGC;COSMIC	15.642	Loss
Other_CAMKK_CAMKK-Meta_CAMKK2_ST	Q13131	PRKAA1	Q96RR4	CAMKK2	S486	E480K	480	Missense	distal	-6	no	17.751	17.782	EPSD	ICGC;COSMIC	15.642	Up-regulation
Other_CAMKK_CAMKK-Meta_CAMKK2_ST	Q13131	PRKAA1	Q96RR4	CAMKK2	S486	D479A	479	Missense	distal	-7	no	17.751	17.789	EPSD	ICGC	15.642	Up-regulation
Other_CAMKK_CAMKK-Meta_CAMKK2_ST	Q13131	PRKAA1	Q96RR4	CAMKK2	T522	S524Y	524	Missense	proximal	2	no	16.398	16.223	EPSD	ICGC;COSMIC	15.642	Down-regulation
Other_CAMKK_CAMKK-Meta_CAMKK2_ST	Q13131	PRKAA1	Q96RR4	CAMKK2	S527	S530C	530	Missense	distal	3	no	22.652	21.518	EPSD	ICGC;COSMIC	15.642	Down-regulation
Other_CAMKK_CAMKK-Meta_CAMKK2_ST	Q13131	PRKAA1	Q96RR4	CAMKK2	S527	S524Y	524	Missense	distal	-3	no	22.652	22.657	EPSD	ICGC;COSMIC	15.642	Up-regulation
Other_CAMKK_CAMKK-Meta_CAMKK2_ST	Q13131	PRKAA1	Q96RR4	CAMKK2	T536	S530C	530	Missense	distal	-6	no	19.204	19.044	EPSD	ICGC;COSMIC	15.642	Down-regulation
Other_CAMKK_CAMKK-Meta_CAMKK2_ST	Q13131	PRKAA1	Q96RR4	CAMKK2	T536	T543K	543	Missense	distal	7	no	19.204	19.200	EPSD	ICGC;COSMIC	15.642	Down-regulation
Other_CAMKK_CAMKK-Meta_CAMKK2_ST	P54646	PRKAA2	Q96RR4	CAMKK2	S173	A180S	180	Missense	distal	7	no	16.125	16.306	EPSD	ICGC	15.642	Up-regulation
Other_CAMKK_CAMKK-Meta_CAMKK2_ST	P54646	PRKAA2	Q96RR4	CAMKK2	S344	S350F	350	Missense	distal	6	no	22.143	22.181	EPSD	ICGC	15.642	Up-regulation
Other_CAMKK_CAMKK-Meta_CAMKK2_ST	P54646	PRKAA2	Q96RR4	CAMKK2	S345	S350F	350	Missense	distal	5	no	20.432	14.642	EPSD	ICGC	15.642	Loss
Other_CAMKK_CAMKK-Meta_CAMKK2_ST	P54646	PRKAA2	Q96RR4	CAMKK2	S350	S350F	350	Missense	central	0	yes	17.660	0.000	EPSD	ICGC	15.642	Loss
Other_CAMKK_CAMKK-Meta_CAMKK2_ST	P54646	PRKAA2	Q96RR4	CAMKK2	S350	D354N	354	Missense	distal	4	no	17.660	15.265	EPSD	ICGC	15.642	Loss
Other_CAMKK_CAMKK-Meta_CAMKK2_ST	P54646	PRKAA2	Q96RR4	CAMKK2	S481	E478D	478	Missense	distal	-3	no	21.659	21.675	EPSD	ICGC	15.642	Up-regulation
Other_CAMKK_CAMKK-Meta_CAMKK2_ST	P54646	PRKAA2	Q96RR4	CAMKK2	S481	R488L	488	Missense	distal	7	no	21.659	21.529	EPSD	ICGC	15.642	Down-regulation
Other_CAMKK_CAMKK-Meta_CAMKK2_ST	P54646	PRKAA2	Q96RR4	CAMKK2	S481	S484P	484	Missense	distal	3	no	21.659	19.604	EPSD	ICGC;COSMIC	15.642	Down-regulation
Other_CAMKK_CAMKK-Meta_CAMKK2_ST	P54646	PRKAA2	Q96RR4	CAMKK2	S501	D503H	503	Missense	proximal	2	no	16.024	15.836	EPSD	ICGC;COSMIC	15.642	Down-regulation
Other_CAMKK_CAMKK-Meta_CAMKK2_ST	P54646	PRKAA2	Q96RR4	CAMKK2	S501	L495V	495	Missense	distal	-6	no	16.024	16.125	EPSD	ICGC	15.642	Up-regulation
Other_CAMKK_CAMKK-Meta_CAMKK2_ST	P54646	PRKAA2	Q96RR4	CAMKK2	S501	P498Q	498	Missense	distal	-3	no	16.024	16.061	EPSD	ICGC	15.642	Up-regulation
Other_CAMKK_CAMKK-Meta_CAMKK2_ST	P54646	PRKAA2	Q96RR4	CAMKK2	S501	A507S	507	Missense	distal	6	no	16.024	15.923	EPSD	ICGC	15.642	Down-regulation
Other_CAMKK_CAMKK-Meta_CAMKK2_ST	P31749	AKT1	Q96RR4	CAMKK2	T308	T305N	305	Missense	distal	-3	no	41.175	41.199	PhosphoSitePlus	ICGC	15.642	Up-regulation
Other_CAMKK_CAMKK-Meta_CAMKK2_ST	P31749	AKT1	Q96RR4	CAMKK2	T450	Q454K	454	Missense	distal	4	no	15.693	13.675	EPSD	ICGC	15.642	Loss
Other_CAMKK_CAMKK-Meta_CAMKK2_ST	P31749	AKT1	Q96RR4	CAMKK2	T450	S457R	457	Missense	distal	7	no	15.693	15.472	EPSD	ICGC	15.642	Loss
Other_CAMKK_CAMKK-Meta_CAMKK2_ST	P31749	AKT1	Q96RR4	CAMKK2	S457	V461L	461	Missense	distal	4	no	15.842	14.439	EPSD	ICGC;COSMIC	15.642	Loss
Other_CAMKK_CAMKK-Meta_CAMKK2_ST	P31749	AKT1	Q96RR4	CAMKK2	S457	M458L	458	Missense	proximal	1	no	15.842	13.145	EPSD	ICGC;COSMIC	15.642	Loss
Other_CAMKK_CAMKK-Meta_CAMKK2_ST	P31749	AKT1	Q96RR4	CAMKK2	S457	Q454K	454	Missense	distal	-3	no	15.842	15.876	EPSD	ICGC	15.642	Up-regulation
Other_CAMKK_CAMKK-Meta_CAMKK2_ST	P31749	AKT1	Q96RR4	CAMKK2	S457	S463R	463	Missense	distal	6	no	15.842	15.902	EPSD	ICGC;COSMIC	15.642	Up-regulation
Other_CAMKK_CAMKK-Meta_CAMKK2_ST	P31749	AKT1	Q96RR4	CAMKK2	S457	S457R	457	Missense	central	0	yes	15.842	0.000	EPSD	ICGC	15.642	Loss
TK_FGFR_FGFR1_Y	P11362	FGFR1	P11362	FGFR1	Y154	P150S	150	Missense	distal	-4	no	7.873	7.186	EPSD;PhosphoSitePlus	ICGC;COSMIC	5.471	Down-regulation
TK_FGFR_FGFR1_Y	P11362	FGFR1	P11362	FGFR1	Y154	T156K	156	Missense	proximal	2	no	7.873	7.663	EPSD;PhosphoSitePlus	ICGC	5.471	Down-regulation
TK_FGFR_FGFR1_Y	P11362	FGFR1	P11362	FGFR1	Y154	A152T	152	Missense	proximal	-2	no	7.873	7.760	EPSD;PhosphoSitePlus	ICGC;COSMIC	5.471	Down-regulation
TK_FGFR_FGFR1_Y	P11362	FGFR1	P11362	FGFR1	Y280	P283Q	283	Missense	distal	3	no	8.681	7.904	EPSD	ICGC	5.471	Down-regulation
TK_FGFR_FGFR1_Y	P11362	FGFR1	P11362	FGFR1	Y280	P285S	285	Missense	distal	5	no	8.681	8.821	EPSD	ICGC;COSMIC;GDSC;CCLE	5.471	Up-regulation
TK_FGFR_FGFR1_Y	P11362	FGFR1	P11362	FGFR1	Y280	S281N	281	Missense	proximal	1	no	8.681	8.680	EPSD	ICGC;COSMIC	5.471	Down-regulation
TK_FGFR_FGFR1_Y	P11362	FGFR1	P11362	FGFR1	Y280	Q284H	284	Missense	distal	4	no	8.681	8.054	EPSD	ICGC;COSMIC	5.471	Down-regulation
TK_FGFR_FGFR1_Y	P11362	FGFR1	P11362	FGFR1	Y307	L311F	311	Missense	distal	4	no	8.158	7.688	EPSD	ICGC;COSMIC	5.471	Down-regulation
TK_FGFR_FGFR1_Y	P11362	FGFR1	P11362	FGFR1	Y701	V704A	704	Missense	distal	3	no	7.463	7.745	EPSD	ICGC;COSMIC	5.471	Up-regulation
TK_FGFR_FGFR1_Y	P11362	FGFR1	P11362	FGFR1	Y766	A759P	759	Missense	distal	-7	no	7.865	7.900	EPSD;PhosphoSitePlus	ICGC;COSMIC	5.471	Up-regulation
TK_FGFR_FGFR1_Y	Q9UBW7	ZMYM2	P11362	FGFR1	Y502	Q496K	496	Missense	distal	-6	no	7.710	7.691	EPSD;PhosphoSitePlus	ICGC;COSMIC	5.471	Down-regulation
TK_FGFR_FGFR1_Y	Q9UBW7	ZMYM2	P11362	FGFR1	Y557	C562F	562	Missense	distal	5	no	7.516	7.261	EPSD;PhosphoSitePlus	ICGC	5.471	Down-regulation
TK_FGFR_FGFR1_Y	Q9UBW7	ZMYM2	P11362	FGFR1	Y557	P560S	560	Missense	distal	3	no	7.516	8.813	EPSD;PhosphoSitePlus	ICGC;COSMIC	5.471	Up-regulation
TK_FGFR_FGFR1_Y	Q9UBW7	ZMYM2	P11362	FGFR1	Y557	Q550E	550	Missense	distal	-7	no	7.516	7.498	EPSD;PhosphoSitePlus	ICGC;COSMIC	5.471	Down-regulation
TK_FGFR_FGFR1_Y	Q9UBW7	ZMYM2	P11362	FGFR1	Y557	Q550K	550	Missense	distal	-7	no	7.516	7.510	EPSD;PhosphoSitePlus	ICGC;COSMIC	5.471	Down-regulation
TK_FGFR_FGFR1_Y	Q9UBW7	ZMYM2	P11362	FGFR1	Y557	M558T	558	Missense	proximal	1	no	7.516	7.519	EPSD;PhosphoSitePlus	ICGC;COSMIC	5.471	Up-regulation
TK_FGFR_FGFR1_Y	Q9UBW7	ZMYM2	P11362	FGFR1	Y595	M599I	599	Missense	distal	4	no	7.727	7.817	PhosphoSitePlus;EPSD	ICGC	5.471	Up-regulation
TK_FGFR_FGFR1_Y	Q9UBW7	ZMYM2	P11362	FGFR1	Y595	N590D	590	Missense	distal	-5	no	7.727	7.694	PhosphoSitePlus;EPSD	ICGC;COSMIC	5.471	Down-regulation
TK_FGFR_FGFR1_Y	Q9UBW7	ZMYM2	P11362	FGFR1	Y605	M599I	599	Missense	distal	-6	no	10.063	10.060	EPSD;PhosphoSitePlus	ICGC	5.471	Down-regulation
TK_FGFR_FGFR1_Y	Q9UBW7	ZMYM2	P11362	FGFR1	Y729	K736N	736	Missense	distal	7	no	8.607	8.223	EPSD;PhosphoSitePlus	ICGC;COSMIC	5.471	Down-regulation
TK_FGFR_FGFR1_Y	Q9UBW7	ZMYM2	P11362	FGFR1	Y1033	V1028I	1028	Missense	distal	-5	no	4.388	5.813	EPSD	ICGC;COSMIC	5.471	Gain
TK_FGFR_FGFR1_Y	Q9P0J1	PDP1	P11362	FGFR1	Y381	P386S	386	Missense	distal	5	no	7.437	7.577	PhosphoSitePlus	ICGC	5.471	Up-regulation
TK_FGFR_FGFR1_Y	Q9P0J1	PDP1	P11362	FGFR1	Y381	N377H	377	Missense	distal	-4	no	7.437	7.635	PhosphoSitePlus	ICGC;COSMIC	5.471	Up-regulation
TK_FGFR_FGFR1_Y	Q15118	PDK1	P11362	FGFR1	Y136	V142L	142	Missense	distal	6	no	7.571	7.568	PhosphoSitePlus;EPSD	ICGC	5.471	Down-regulation
TK_FGFR_FGFR1_Y	Q15118	PDK1	P11362	FGFR1	Y243	C240F	240	Missense	distal	-3	no	8.210	8.282	EPSD;PhosphoSitePlus	ICGC;COSMIC	5.471	Up-regulation
TK_FGFR_FGFR1_Y	Q15118	PDK1	P11362	FGFR1	Y243	R238C	238	Missense	distal	-5	no	8.210	8.679	EPSD;PhosphoSitePlus	ICGC	5.471	Up-regulation
TK_FGFR_FGFR1_Y	Q15118	PDK1	P11362	FGFR1	Y243	P248H	248	Missense	distal	5	no	8.210	7.250	EPSD;PhosphoSitePlus	ICGC;COSMIC	5.471	Down-regulation
TK_FGFR_FGFR1_Y	Q15118	PDK1	P11362	FGFR1	Y244	C240F	240	Missense	distal	-4	no	8.792	8.827	EPSD;PhosphoSitePlus	ICGC;COSMIC	5.471	Up-regulation
TK_FGFR_FGFR1_Y	Q15118	PDK1	P11362	FGFR1	Y244	P248H	248	Missense	distal	4	no	8.792	8.248	EPSD;PhosphoSitePlus	ICGC;COSMIC	5.471	Down-regulation
TK_FGFR_FGFR1_Y	P00338	LDHA	P11362	FGFR1	Y83	G80V	80	Missense	distal	-3	no	7.657	6.792	EPSD;PhosphoSitePlus	ICGC;COSMIC	5.471	Down-regulation
TK_FGFR_FGFR1_Y	P00338	LDHA	P11362	FGFR1	Y83	K81R	81	Missense	proximal	-2	no	7.657	7.656	EPSD;PhosphoSitePlus	ICGC;COSMIC	5.471	Down-regulation
AGC_GRK_BARK_GRK3_ST	P07550	ADRB2	P35626	GRK3	S246	R239H	239	Missense	distal	-7	no	14.215	11.773	EPSD	ICGC;COSMIC	9.327	Down-regulation
AGC_GRK_BARK_GRK3_ST	P07550	ADRB2	P35626	GRK3	S246	V242D	242	Missense	distal	-4	no	14.215	14.342	EPSD	ICGC;COSMIC	9.327	Up-regulation
AGC_GRK_BARK_GRK3_ST	P07550	ADRB2	P35626	GRK3	S246	G252V	252	Missense	distal	6	no	14.215	14.157	EPSD	ICGC	9.327	Down-regulation
AGC_GRK_BARK_GRK3_ST	P07550	ADRB2	P35626	GRK3	S246	H241Y	241	Missense	distal	-5	no	14.215	13.999	EPSD	ICGC	9.327	Down-regulation
AGC_GRK_BARK_GRK3_ST	P07550	ADRB2	P35626	GRK3	S355	N352H	352	Missense	distal	-3	no	22.034	21.462	PhosphoSitePlus;EPSD	ICGC	9.327	Down-regulation
AGC_GRK_BARK_GRK3_ST	P07550	ADRB2	P35626	GRK3	S356	N352H	352	Missense	distal	-4	no	20.543	19.755	EPSD;PhosphoSitePlus	ICGC	9.327	Down-regulation
AGC_GRK_BARK_GRK3_ST	P07550	ADRB2	P35626	GRK3	S364	S364R	364	Missense	central	0	yes	17.055	0.000	EPSD	ICGC	9.327	Loss
AGC_GRK_BARK_GRK3_ST	P21731	TBXA2R	P35626	GRK3	S239	M244T	244	Missense	distal	5	no	20.371	20.192	PhosphoSitePlus;EPSD	ICGC;COSMIC	9.327	Down-regulation
AGC_GRK_BARK_GRK3_ST	P21731	TBXA2R	P35626	GRK3	S239	S239Y	239	Missense	central	0	yes	20.371	0.000	PhosphoSitePlus;EPSD	ICGC	9.327	Loss
AGC_GRK_BARK_GRK3_ST	P21731	TBXA2R	P35626	GRK3	S239	R237G	237	Missense	proximal	-2	no	20.371	18.102	PhosphoSitePlus;EPSD	ICGC;COSMIC	9.327	Down-regulation
AGC_GRK_BARK_GRK3_ST	P21731	TBXA2R	P35626	GRK3	S239	R235H	235	Missense	distal	-4	no	20.371	19.190	PhosphoSitePlus;EPSD	ICGC;COSMIC	9.327	Down-regulation
AGC_GRK_BARK_GRK3_ST	P21731	TBXA2R	P35626	GRK3	S239	E242K	242	Missense	distal	3	no	20.371	19.820	PhosphoSitePlus;EPSD	ICGC;COSMIC	9.327	Down-regulation
AGC_GRK_BARK_GRK3_ST	P41146	OPRL1	P35626	GRK3	S164	V161L	161	Missense	distal	-3	no	12.344	12.107	EPSD	ICGC	9.327	Down-regulation
AGC_GRK_BARK_GRK3_ST	P41146	OPRL1	P35626	GRK3	S165	V161L	161	Missense	distal	-4	no	11.421	10.836	EPSD	ICGC	9.327	Down-regulation
AGC_GRK_BARK_GRK3_ST	P41146	OPRL1	P35626	GRK3	S165	V172M	172	Missense	distal	7	no	11.421	11.861	EPSD	ICGC	9.327	Up-regulation
AGC_SGK_SGK3_ST	Q96J02	ITCH	Q96BR1	SGK3	T214	T218A	218	Missense	distal	4	no	2.257	2.251	EPSD	ICGC;COSMIC	2.112	Down-regulation
AGC_SGK_SGK3_ST	Q96J02	ITCH	Q96BR1	SGK3	T214	S221L	221	Missense	distal	7	no	2.257	2.248	EPSD	ICGC;COSMIC	2.112	Down-regulation
AGC_SGK_SGK3_ST	Q96J02	ITCH	Q96BR1	SGK3	T214	S208F	208	Missense	distal	-6	no	2.257	2.276	EPSD	ICGC;COSMIC	2.112	Up-regulation
AGC_SGK_SGK3_ST	Q96J02	ITCH	Q96BR1	SGK3	T214	G207V	207	Missense	distal	-7	no	2.257	2.299	EPSD	ICGC	2.112	Up-regulation
AGC_SGK_SGK3_ST	Q96J02	ITCH	Q96BR1	SGK3	T214	E213D	213	Missense	proximal	-1	no	2.257	2.537	EPSD	ICGC	2.112	Up-regulation
AGC_SGK_SGK3_ST	Q96J02	ITCH	Q96BR1	SGK3	T218	T218A	218	Missense	central	0	yes	4.879	0.000	EPSD	ICGC;COSMIC	2.112	Loss
AGC_SGK_SGK3_ST	Q96J02	ITCH	Q96BR1	SGK3	T218	S221L	221	Missense	distal	3	no	4.879	4.776	EPSD	ICGC;COSMIC	2.112	Down-regulation
AGC_SGK_SGK3_ST	Q96J02	ITCH	Q96BR1	SGK3	T218	E213D	213	Missense	distal	-5	no	4.879	4.621	EPSD	ICGC	2.112	Down-regulation
AGC_SGK_SGK3_ST	Q96J02	ITCH	Q96BR1	SGK3	T263	P267S	267	Missense	distal	4	no	2.814	2.825	EPSD	ICGC;COSMIC	2.112	Up-regulation
AGC_SGK_SGK3_ST	Q96J02	ITCH	Q96BR1	SGK3	T385	R388S	388	Missense	distal	3	no	8.899	7.121	EPSD;PhosphoSitePlus	ICGC	2.112	Down-regulation
AGC_SGK_SGK3_ST	Q96J02	ITCH	Q96BR1	SGK3	T385	T385M	385	Missense	central	0	yes	8.899	0.000	EPSD;PhosphoSitePlus	ICGC;COSMIC	2.112	Loss
AGC_SGK_SGK3_ST	Q96J02	ITCH	Q96BR1	SGK3	T385	E392D	392	Missense	distal	7	no	8.899	8.902	EPSD;PhosphoSitePlus	ICGC	2.112	Up-regulation
AGC_SGK_SGK3_ST	Q96J02	ITCH	Q96BR1	SGK3	S450	V454A	454	Missense	distal	4	no	8.912	8.850	PhosphoSitePlus;EPSD	ICGC	2.112	Down-regulation
AGC_SGK_SGK3_ST	Q96J02	ITCH	Q96BR1	SGK3	S450	G452C	452	Missense	proximal	2	no	8.912	8.652	PhosphoSitePlus;EPSD	ICGC	2.112	Down-regulation
AGC_SGK_SGK3_ST	Q96J02	ITCH	Q96BR1	SGK3	S450	G452V	452	Missense	proximal	2	no	8.912	8.624	PhosphoSitePlus;EPSD	ICGC	2.112	Down-regulation
AGC_SGK_SGK3_ST	Q96J02	ITCH	Q96BR1	SGK3	S450	K446N	446	Missense	distal	-4	no	8.912	8.842	PhosphoSitePlus;EPSD	ICGC;COSMIC	2.112	Down-regulation
AGC_SGK_SGK3_ST	Q96J02	ITCH	Q96BR1	SGK3	T504	N500S	500	Missense	distal	-4	no	4.318	4.338	EPSD	ICGC	2.112	Up-regulation
AGC_SGK_SGK3_ST	Q96J02	ITCH	Q96BR1	SGK3	T504	V497L	497	Missense	distal	-7	no	4.318	4.331	EPSD	ICGC	2.112	Up-regulation
AGC_SGK_SGK3_ST	Q96J02	ITCH	Q96BR1	SGK3	T504	I507V	507	Missense	distal	3	no	4.318	4.213	EPSD	ICGC;COSMIC	2.112	Down-regulation
AGC_SGK_SGK3_ST	Q96J02	ITCH	Q96BR1	SGK3	T505	N500S	500	Missense	distal	-5	no	6.089	6.142	EPSD	ICGC	2.112	Up-regulation
AGC_SGK_SGK3_ST	Q96J02	ITCH	Q96BR1	SGK3	T505	I507V	507	Missense	proximal	2	no	6.089	6.114	EPSD	ICGC;COSMIC	2.112	Up-regulation
AGC_SGK_SGK3_ST	Q13045	FLII	Q96BR1	SGK3	S90	G95R	95	Missense	distal	5	no	3.839	3.940	EPSD	ICGC;COSMIC	2.112	Up-regulation
AGC_SGK_SGK3_ST	Q13045	FLII	Q96BR1	SGK3	S90	A88D	88	Missense	proximal	-2	no	3.839	4.134	EPSD	ICGC	2.112	Up-regulation
AGC_SGK_SGK3_ST	Q13045	FLII	Q96BR1	SGK3	S436	R431K	431	Missense	distal	-5	no	8.948	7.253	PhosphoSitePlus;EPSD	ICGC;COSMIC	2.112	Down-regulation
AGC_SGK_SGK3_ST	Q13045	FLII	Q96BR1	SGK3	S436	D439G	439	Missense	distal	3	no	8.948	8.213	PhosphoSitePlus;EPSD	ICGC	2.112	Down-regulation
AGC_SGK_SGK3_ST	Q13045	FLII	Q96BR1	SGK3	T665	T669M	669	Missense	distal	4	no	2.275	2.276	EPSD	ICGC;COSMIC	2.112	Up-regulation
AGC_SGK_SGK3_ST	Q13045	FLII	Q96BR1	SGK3	T670	T669M	669	Missense	proximal	-1	no	2.475	1.822	EPSD	ICGC;COSMIC	2.112	Loss
AGC_SGK_SGK3_ST	Q13045	FLII	Q96BR1	SGK3	T670	A672V	672	Missense	proximal	2	no	2.475	2.183	EPSD	ICGC;COSMIC	2.112	Down-regulation
AGC_SGK_SGK3_ST	Q13045	FLII	Q96BR1	SGK3	T670	R673Q	673	Missense	distal	3	no	2.475	0.812	EPSD	ICGC;COSMIC	2.112	Loss
AGC_SGK_SGK3_ST	Q13045	FLII	Q96BR1	SGK3	T818	A817V	817	Missense	proximal	-1	no	9.197	8.778	EPSD;PhosphoSitePlus	ICGC;COSMIC	2.112	Down-regulation
AGC_SGK_SGK3_ST	Q13045	FLII	Q96BR1	SGK3	T818	V819A	819	Missense	proximal	1	no	9.197	9.229	EPSD;PhosphoSitePlus	ICGC	2.112	Up-regulation
AGC_SGK_SGK3_ST	P49841	GSK3B	Q96BR1	SGK3	T7	A11S	11	Missense	distal	4	no	4.624	4.691	EPSD	ICGC;COSMIC	2.112	Up-regulation
AGC_SGK_SGK3_ST	P49841	GSK3B	Q96BR1	SGK3	S9	A11S	11	Missense	proximal	2	no	8.615	8.726	PhosphoSitePlus	ICGC;COSMIC	2.112	Up-regulation
AGC_SGK_SGK3_ST	P49841	GSK3B	Q96BR1	SGK3	S35	D33E	33	Missense	proximal	-2	no	2.319	1.890	EPSD	ICGC	2.112	Loss
AGC_SGK_SGK3_ST	P49841	GSK3B	Q96BR1	SGK3	S55	D49E	49	Missense	distal	-6	no	2.133	2.134	EPSD	ICGC	2.112	Up-regulation
AGC_SGK_SGK3_ST	P49841	GSK3B	Q96BR1	SGK3	S55	Q52K	52	Missense	distal	-3	no	2.133	2.354	EPSD	ICGC	2.112	Up-regulation
AGC_SGK_SGK3_ST	P49841	GSK3B	Q96BR1	SGK3	S55	E53K	53	Missense	proximal	-2	no	2.133	2.693	EPSD	ICGC;COSMIC	2.112	Up-regulation
AGC_SGK_SGK3_ST	P49841	GSK3B	Q96BR1	SGK3	S147	A149D	149	Missense	proximal	2	no	4.301	4.180	EPSD	ICGC	2.112	Down-regulation
AGC_SGK_SGK3_ST	P49841	GSK3B	Q96BR1	SGK3	S147	T152R	152	Missense	distal	5	no	4.301	4.392	EPSD	ICGC;COSMIC	2.112	Up-regulation
AGC_SGK_SGK3_ST	P49841	GSK3B	Q96BR1	SGK3	S147	Q151R	151	Missense	distal	4	no	4.301	4.365	EPSD	ICGC;COSMIC	2.112	Up-regulation
AGC_SGK_SGK3_ST	P49841	GSK3B	Q96BR1	SGK3	T402	G406R	406	Missense	distal	4	no	2.478	2.522	EPSD	ICGC;COSMIC	2.112	Up-regulation
AGC_SGK_SGK3_ST	P49841	GSK3B	Q96BR1	SGK3	T402	A397T	397	Missense	distal	-5	no	2.478	2.412	EPSD	ICGC;COSMIC	2.112	Down-regulation
AGC_SGK_SGK3_ST	P49841	GSK3B	Q96BR1	SGK3	T402	S398L	398	Missense	distal	-4	no	2.478	2.421	EPSD	ICGC;COSMIC	2.112	Down-regulation
AGC_SGK_SGK3_ST	P49841	GSK3B	Q96BR1	SGK3	T408	G406R	406	Missense	proximal	-2	no	4.316	4.158	EPSD	ICGC;COSMIC	2.112	Down-regulation
AGC_SGK_SGK3_ST	P49841	GSK3B	Q96BR1	SGK3	T408	S415T	415	Missense	distal	7	no	4.316	4.320	EPSD	ICGC;COSMIC	2.112	Up-regulation
Atypical_PIKK_ATM_ATM_ST	Q9NVI1	FANCI	Q13315	ATM	S57	I50T	50	Missense	distal	-7	no	9.177	9.761	EPSD	ICGC	9.540	Gain
Atypical_PIKK_ATM_ATM_ST	Q9NVI1	FANCI	Q13315	ATM	S57	G53S	53	Missense	distal	-4	no	9.177	9.966	EPSD	ICGC	9.540	Gain
Atypical_PIKK_ATM_ATM_ST	Q9NVI1	FANCI	Q13315	ATM	S407	P408T	408	Missense	proximal	1	no	11.361	6.354	EPSD	ICGC;COSMIC	9.540	Loss
Atypical_PIKK_ATM_ATM_ST	Q9NVI1	FANCI	Q13315	ATM	S559	V564F	564	Missense	distal	5	no	14.867	14.961	EPSD;PhosphoSitePlus	ICGC	9.540	Up-regulation
Atypical_PIKK_ATM_ATM_ST	Q9NVI1	FANCI	Q13315	ATM	S565	V564F	564	Missense	proximal	-1	no	13.688	13.685	EPSD	ICGC	9.540	Down-regulation
Atypical_PIKK_ATM_ATM_ST	Q9NVI1	FANCI	Q13315	ATM	S565	V567F	567	Missense	proximal	2	no	13.688	13.101	EPSD	ICGC	9.540	Down-regulation
Atypical_PIKK_ATM_ATM_ST	Q9NVI1	FANCI	Q13315	ATM	S629	Y635C	635	Missense	distal	6	no	14.137	14.106	EPSD	ICGC;COSMIC	9.540	Down-regulation
Atypical_PIKK_ATM_ATM_ST	Q9NVI1	FANCI	Q13315	ATM	S629	S622L	622	Missense	distal	-7	no	14.137	13.549	EPSD	ICGC	9.540	Down-regulation
Atypical_PIKK_ATM_ATM_ST	Q9NVI1	FANCI	Q13315	ATM	S726	A727E	727	Missense	proximal	1	no	11.387	12.363	EPSD	ICGC;COSMIC	9.540	Up-regulation
Atypical_PIKK_ATM_ATM_ST	Q9NVI1	FANCI	Q13315	ATM	S730	A727E	727	Missense	distal	-3	no	16.945	17.231	EPSD;PhosphoSitePlus	ICGC;COSMIC	9.540	Up-regulation
Atypical_PIKK_ATM_ATM_ST	Q9NVI1	FANCI	Q13315	ATM	S828	R833W	833	Missense	distal	5	no	9.870	9.894	EPSD	ICGC;COSMIC	9.540	Up-regulation
Atypical_PIKK_ATM_ATM_ST	Q9NVI1	FANCI	Q13315	ATM	S972	N968S	968	Missense	distal	-4	no	15.432	16.360	PhosphoSitePlus;EPSD	ICGC	9.540	Up-regulation
Atypical_PIKK_ATM_ATM_ST	Q9NVI1	FANCI	Q13315	ATM	S1111	V1110L	1110	Missense	proximal	-1	no	15.807	16.095	EPSD	ICGC	9.540	Up-regulation
Atypical_PIKK_ATM_ATM_ST	Q9NVI1	FANCI	Q13315	ATM	S1111	S1116T	1116	Missense	distal	5	no	15.807	15.790	EPSD	ICGC;COSMIC	9.540	Down-regulation
Atypical_PIKK_ATM_ATM_ST	Q9NVI1	FANCI	Q13315	ATM	S1121	S1116T	1116	Missense	distal	-5	no	15.858	15.769	EPSD;PhosphoSitePlus	ICGC;COSMIC	9.540	Down-regulation
Atypical_PIKK_ATM_ATM_ST	O60934	NBN	Q13315	ATM	S58	F52L	52	Missense	distal	-6	no	16.155	16.398	EPSD	ICGC;COSMIC	9.540	Up-regulation
Atypical_PIKK_ATM_ATM_ST	O60934	NBN	Q13315	ATM	S58	S53Y	53	Missense	distal	-5	no	16.155	16.179	EPSD	ICGC	9.540	Up-regulation
Atypical_PIKK_ATM_ATM_ST	O60934	NBN	Q13315	ATM	S278	T280K	280	Missense	proximal	2	no	16.657	16.099	EPSD;PhosphoSitePlus	ICGC	9.540	Down-regulation
Atypical_PIKK_ATM_ATM_ST	O60934	NBN	Q13315	ATM	S278	N277K	277	Missense	proximal	-1	no	16.657	16.519	EPSD;PhosphoSitePlus	ICGC	9.540	Down-regulation
Atypical_PIKK_ATM_ATM_ST	P78527	PRKDC	Q13315	ATM	S245	Q243R	243	Missense	proximal	-2	no	10.698	10.380	EPSD	ICGC	9.540	Down-regulation
Atypical_PIKK_ATM_ATM_ST	P78527	PRKDC	Q13315	ATM	S245	M238V	238	Missense	distal	-7	no	10.698	10.693	EPSD	ICGC;COSMIC;GDSC	9.540	Down-regulation
Atypical_PIKK_ATM_ATM_ST	P78527	PRKDC	Q13315	ATM	S245	N250Y	250	Missense	distal	5	no	10.698	10.788	EPSD	ICGC;COSMIC	9.540	Up-regulation
Atypical_PIKK_ATM_ATM_ST	P78527	PRKDC	Q13315	ATM	T398	K393N	393	Missense	distal	-5	no	13.561	13.617	EPSD	ICGC;COSMIC	9.540	Up-regulation
Atypical_PIKK_ATM_ATM_ST	P78527	PRKDC	Q13315	ATM	T398	Q399K	399	Missense	proximal	1	no	13.561	6.713	EPSD	ICGC	9.540	Loss
Atypical_PIKK_ATM_ATM_ST	P78527	PRKDC	Q13315	ATM	S505	G512E	512	Missense	distal	7	no	10.220	10.175	EPSD	ICGC;COSMIC	9.540	Down-regulation
Atypical_PIKK_ATM_ATM_ST	P78527	PRKDC	Q13315	ATM	S511	G512E	512	Missense	proximal	1	no	9.941	10.518	EPSD	ICGC;COSMIC	9.540	Up-regulation
Atypical_PIKK_ATM_ATM_ST	P78527	PRKDC	Q13315	ATM	S694	Y701F	701	Missense	distal	7	no	10.694	10.720	EPSD	ICGC;COSMIC	9.540	Up-regulation
Atypical_PIKK_ATM_ATM_ST	P78527	PRKDC	Q13315	ATM	S876	M880I	880	Missense	distal	4	no	10.781	11.184	EPSD	ICGC;COSMIC	9.540	Up-regulation
Atypical_PIKK_ATM_ATM_ST	P78527	PRKDC	Q13315	ATM	S876	T872K	872	Missense	distal	-4	no	10.781	10.471	EPSD	ICGC	9.540	Down-regulation
Atypical_PIKK_ATM_ATM_ST	P78527	PRKDC	Q13315	ATM	S876	D877Y	877	Missense	proximal	1	no	10.781	11.096	EPSD	ICGC	9.540	Up-regulation
Atypical_PIKK_ATM_ATM_ST	P78527	PRKDC	Q13315	ATM	S882	A885T	885	Missense	distal	3	no	9.878	9.903	EPSD	ICGC;COSMIC	9.540	Up-regulation
Atypical_PIKK_ATM_ATM_ST	P78527	PRKDC	Q13315	ATM	S882	M880I	880	Missense	proximal	-2	no	9.878	9.627	EPSD	ICGC;COSMIC	9.540	Down-regulation
Atypical_PIKK_ATM_ATM_ST	P78527	PRKDC	Q13315	ATM	S882	W886R	886	Missense	distal	4	no	9.878	9.734	EPSD	ICGC;COSMIC	9.540	Down-regulation
Atypical_PIKK_ATM_ATM_ST	P78527	PRKDC	Q13315	ATM	S882	D877Y	877	Missense	distal	-5	no	9.878	10.113	EPSD	ICGC	9.540	Up-regulation
Atypical_PIKK_ATM_ATM_ST	P78527	PRKDC	Q13315	ATM	S1162	R1155Q	1155	Missense	distal	-7	no	9.795	9.995	EPSD	ICGC	9.540	Up-regulation
Atypical_PIKK_ATM_ATM_ST	P78527	PRKDC	Q13315	ATM	S1203	P1199T	1199	Missense	distal	-4	no	12.014	12.300	EPSD	ICGC	9.540	Up-regulation
Atypical_PIKK_ATM_ATM_ST	P78527	PRKDC	Q13315	ATM	S1203	P1199Q	1199	Missense	distal	-4	no	12.014	12.238	EPSD	ICGC;COSMIC	9.540	Up-regulation
Atypical_PIKK_ATM_ATM_ST	P78527	PRKDC	Q13315	ATM	S1203	P1204H	1204	Missense	proximal	1	no	12.014	1.907	EPSD	ICGC;COSMIC	9.540	Loss
Atypical_PIKK_ATM_ATM_ST	P78527	PRKDC	Q13315	ATM	S1203	R1202I	1202	Missense	proximal	-1	no	12.014	12.168	EPSD	ICGC;COSMIC	9.540	Up-regulation
Atypical_PIKK_ATM_ATM_ST	P78527	PRKDC	Q13315	ATM	T1793	R1787S	1787	Missense	distal	-6	no	12.837	13.018	EPSD	ICGC	9.540	Up-regulation
Atypical_PIKK_ATM_ATM_ST	P78527	PRKDC	Q13315	ATM	S2029	S2026F	2026	Missense	distal	-3	no	9.110	10.182	EPSD	ICGC	9.540	Gain
Atypical_PIKK_ATM_ATM_ST	P78527	PRKDC	Q13315	ATM	S3893	A3899D	3899	Missense	distal	6	no	12.367	12.339	EPSD	ICGC	9.540	Down-regulation
Atypical_PIKK_ATM_ATM_ST	Q99801	NKX3-1	Q13315	ATM	T134	E138K	138	Missense	distal	4	no	13.822	14.200	EPSD;PhosphoSitePlus	ICGC	9.540	Up-regulation
Atypical_PIKK_ATM_ATM_ST	Q99801	NKX3-1	Q13315	ATM	T166	W171G	171	Missense	distal	5	no	14.014	14.003	PhosphoSitePlus;EPSD	ICGC;COSMIC	9.540	Down-regulation
Atypical_PIKK_ATM_ATM_ST	Q12888	TP53BP1	Q13315	ATM	S6	T4A	4	Missense	proximal	-2	no	12.973	12.873	EPSD	ICGC	9.540	Down-regulation
Atypical_PIKK_ATM_ATM_ST	Q12888	TP53BP1	Q13315	ATM	S6	G5E	5	Missense	proximal	-1	no	12.973	13.375	EPSD	ICGC;COSMIC	9.540	Up-regulation
Atypical_PIKK_ATM_ATM_ST	Q12888	TP53BP1	Q13315	ATM	S25	D24V	24	Missense	proximal	-1	no	15.892	15.523	EPSD;PhosphoSitePlus	ICGC;COSMIC	9.540	Down-regulation
Atypical_PIKK_ATM_ATM_ST	Q12888	TP53BP1	Q13315	ATM	S29	D24V	24	Missense	distal	-5	no	14.774	15.099	PhosphoSitePlus;EPSD	ICGC;COSMIC	9.540	Up-regulation
Atypical_PIKK_ATM_ATM_ST	Q12888	TP53BP1	Q13315	ATM	S105	I104F	104	Missense	proximal	-1	no	12.866	12.660	EPSD	ICGC;COSMIC	9.540	Down-regulation
Atypical_PIKK_ATM_ATM_ST	Q12888	TP53BP1	Q13315	ATM	S105	Q106K	106	Missense	proximal	1	no	12.866	6.017	EPSD	ICGC;COSMIC	9.540	Loss
Atypical_PIKK_ATM_ATM_ST	Q12888	TP53BP1	Q13315	ATM	S105	I104M	104	Missense	proximal	-1	no	12.866	12.795	EPSD	ICGC;COSMIC	9.540	Down-regulation
Atypical_PIKK_ATM_ATM_ST	Q12888	TP53BP1	Q13315	ATM	S105	Q106E	106	Missense	proximal	1	no	12.866	6.969	EPSD	ICGC;COSMIC	9.540	Loss
Atypical_PIKK_ATM_ATM_ST	Q12888	TP53BP1	Q13315	ATM	S166	L173M	173	Missense	distal	7	no	14.193	14.207	EPSD	ICGC	9.540	Up-regulation
Atypical_PIKK_ATM_ATM_ST	Q12888	TP53BP1	Q13315	ATM	S176	E183K	183	Missense	distal	7	no	13.282	13.309	EPSD	ICGC	9.540	Up-regulation
Atypical_PIKK_ATM_ATM_ST	Q12888	TP53BP1	Q13315	ATM	S176	L173M	173	Missense	distal	-3	no	13.282	13.428	EPSD	ICGC	9.540	Up-regulation
Atypical_PIKK_ATM_ATM_ST	Q12888	TP53BP1	Q13315	ATM	S176	Q179H	179	Missense	distal	3	no	13.282	13.422	EPSD	ICGC	9.540	Up-regulation
Atypical_PIKK_ATM_ATM_ST	Q12888	TP53BP1	Q13315	ATM	S178	E183K	183	Missense	distal	5	no	14.527	14.702	EPSD	ICGC	9.540	Up-regulation
Atypical_PIKK_ATM_ATM_ST	Q12888	TP53BP1	Q13315	ATM	S178	L173M	173	Missense	distal	-5	no	14.527	14.589	EPSD	ICGC	9.540	Up-regulation
Atypical_PIKK_ATM_ATM_ST	Q12888	TP53BP1	Q13315	ATM	S178	Q179H	179	Missense	proximal	1	no	14.527	-0.382	EPSD	ICGC	9.540	Loss
Atypical_PIKK_ATM_ATM_ST	Q12888	TP53BP1	Q13315	ATM	S233	S233N	233	Missense	central	0	yes	10.013	0.000	EPSD	ICGC	9.540	Loss
Atypical_PIKK_ATM_ATM_ST	Q12888	TP53BP1	Q13315	ATM	S233	Q231L	231	Missense	proximal	-2	no	10.013	9.748	EPSD	ICGC;COSMIC	9.540	Down-regulation
Atypical_PIKK_ATM_ATM_ST	Q12888	TP53BP1	Q13315	ATM	S259	P266H	266	Missense	distal	7	no	9.579	9.589	EPSD	ICGC;COSMIC	9.540	Up-regulation
Atypical_PIKK_ATM_ATM_ST	Q12888	TP53BP1	Q13315	ATM	S259	P255Q	255	Missense	distal	-4	no	9.579	9.804	EPSD	ICGC;COSMIC	9.540	Up-regulation
Atypical_PIKK_ATM_ATM_ST	Q12888	TP53BP1	Q13315	ATM	S259	E260G	260	Missense	proximal	1	no	9.579	9.002	EPSD	ICGC;COSMIC	9.540	Loss
Atypical_PIKK_ATM_ATM_ST	Q12888	TP53BP1	Q13315	ATM	S294	E296D	296	Missense	proximal	2	no	11.772	11.641	EPSD	ICGC;COSMIC	9.540	Down-regulation
Atypical_PIKK_ATM_ATM_ST	Q12888	TP53BP1	Q13315	ATM	S294	S287I	287	Missense	distal	-7	no	11.772	11.108	EPSD	ICGC;COSMIC	9.540	Down-regulation
Atypical_PIKK_ATM_ATM_ST	Q12888	TP53BP1	Q13315	ATM	S294	K293M	293	Missense	proximal	-1	no	11.772	11.673	EPSD	ICGC;COSMIC	9.540	Down-regulation
Atypical_PIKK_ATM_ATM_ST	Q12888	TP53BP1	Q13315	ATM	T302	E296D	296	Missense	distal	-6	no	15.386	15.172	EPSD	ICGC;COSMIC	9.540	Down-regulation
Atypical_PIKK_ATM_ATM_ST	Q12888	TP53BP1	Q13315	ATM	T302	Q309K	309	Missense	distal	7	no	15.386	15.399	EPSD	ICGC	9.540	Up-regulation
Atypical_PIKK_ATM_ATM_ST	Q12888	TP53BP1	Q13315	ATM	T302	D305Y	305	Missense	distal	3	no	15.386	15.445	EPSD	ICGC	9.540	Up-regulation
Atypical_PIKK_ATM_ATM_ST	Q12888	TP53BP1	Q13315	ATM	T334	A336D	336	Missense	proximal	2	no	9.437	10.400	EPSD	ICGC	9.540	Gain
Atypical_PIKK_ATM_ATM_ST	Q12888	TP53BP1	Q13315	ATM	S366	S359Y	359	Missense	distal	-7	no	11.215	10.920	EPSD	ICGC;COSMIC	9.540	Down-regulation
Atypical_PIKK_ATM_ATM_ST	Q12888	TP53BP1	Q13315	ATM	S380	P381S	381	Missense	proximal	1	no	9.831	2.856	EPSD	ICGC;COSMIC	9.540	Loss
Atypical_PIKK_ATM_ATM_ST	Q12888	TP53BP1	Q13315	ATM	S380	S379C	379	Missense	proximal	-1	no	9.831	9.632	EPSD	ICGC	9.540	Down-regulation
Atypical_PIKK_ATM_ATM_ST	Q12888	TP53BP1	Q13315	ATM	S380	S379N	379	Missense	proximal	-1	no	9.831	9.776	EPSD	ICGC	9.540	Down-regulation
Atypical_PIKK_ATM_ATM_ST	Q12888	TP53BP1	Q13315	ATM	S452	S452C	452	Missense	central	0	yes	14.112	0.000	EPSD	ICGC;COSMIC	9.540	Loss
Atypical_PIKK_ATM_ATM_ST	Q12888	TP53BP1	Q13315	ATM	S490	E494D	494	Missense	distal	4	no	9.194	9.699	EPSD	ICGC	9.540	Gain
Atypical_PIKK_ATM_ATM_ST	Q12888	TP53BP1	Q13315	ATM	S500	S500F	500	Missense	central	0	yes	12.973	0.000	EPSD	ICGC;COSMIC	9.540	Loss
Atypical_PIKK_ATM_ATM_ST	Q12888	TP53BP1	Q13315	ATM	S500	E494D	494	Missense	distal	-6	no	12.973	12.759	EPSD	ICGC	9.540	Down-regulation
Atypical_PIKK_ATM_ATM_ST	Q12888	TP53BP1	Q13315	ATM	S500	K498N	498	Missense	proximal	-2	no	12.973	13.189	EPSD	ICGC;COSMIC	9.540	Up-regulation
Atypical_PIKK_ATM_ATM_ST	Q12888	TP53BP1	Q13315	ATM	S523	P526Q	526	Missense	distal	3	no	14.307	14.238	EPSD	ICGC;COSMIC	9.540	Down-regulation
Atypical_PIKK_ATM_ATM_ST	Q12888	TP53BP1	Q13315	ATM	S523	M528I	528	Missense	distal	5	no	14.307	14.331	EPSD	ICGC;COSMIC	9.540	Up-regulation
Atypical_PIKK_ATM_ATM_ST	Q12888	TP53BP1	Q13315	ATM	S523	S523N	523	Missense	central	0	yes	14.307	0.000	EPSD	ICGC	9.540	Loss
Atypical_PIKK_ATM_ATM_ST	Q12888	TP53BP1	Q13315	ATM	S523	K527N	527	Missense	distal	4	no	14.307	14.354	EPSD	ICGC;COSMIC	9.540	Up-regulation
Atypical_PIKK_ATM_ATM_ST	Q12888	TP53BP1	Q13315	ATM	S525	P526Q	526	Missense	proximal	1	no	10.644	15.446	EPSD	ICGC;COSMIC	9.540	Up-regulation
Atypical_PIKK_ATM_ATM_ST	Q12888	TP53BP1	Q13315	ATM	S525	M528I	528	Missense	distal	3	no	10.644	10.890	EPSD	ICGC;COSMIC	9.540	Up-regulation
Atypical_PIKK_ATM_ATM_ST	Q12888	TP53BP1	Q13315	ATM	S525	S523N	523	Missense	proximal	-2	no	10.644	10.465	EPSD	ICGC	9.540	Down-regulation
Atypical_PIKK_ATM_ATM_ST	Q12888	TP53BP1	Q13315	ATM	S525	K527N	527	Missense	proximal	2	no	10.644	10.823	EPSD	ICGC;COSMIC	9.540	Up-regulation
Atypical_PIKK_ATM_ATM_ST	Q12888	TP53BP1	Q13315	ATM	T543	P550H	550	Missense	distal	7	no	13.539	13.549	EPSD	ICGC;COSMIC	9.540	Up-regulation
Atypical_PIKK_ATM_ATM_ST	Q12888	TP53BP1	Q13315	ATM	T543	T548M	548	Missense	distal	5	no	13.539	13.740	EPSD	ICGC;COSMIC	9.540	Up-regulation
Atypical_PIKK_ATM_ATM_ST	Q12888	TP53BP1	Q13315	ATM	T543	N542I	542	Missense	proximal	-1	no	13.539	13.373	EPSD	ICGC;COSMIC	9.540	Down-regulation
Atypical_PIKK_ATM_ATM_ST	Q12888	TP53BP1	Q13315	ATM	T543	E546D	546	Missense	distal	3	no	13.539	13.898	EPSD	ICGC;COSMIC	9.540	Up-regulation
Atypical_PIKK_ATM_ATM_ST	Q12888	TP53BP1	Q13315	ATM	T543	D539E	539	Missense	distal	-4	no	13.539	13.822	EPSD	ICGC;COSMIC	9.540	Up-regulation
Atypical_PIKK_ATM_ATM_ST	Q12888	TP53BP1	Q13315	ATM	T543	P550S	550	Missense	distal	7	no	13.539	13.520	EPSD	ICGC;COSMIC	9.540	Down-regulation
Atypical_PIKK_ATM_ATM_ST	Q12888	TP53BP1	Q13315	ATM	T543	E549K	549	Missense	distal	6	no	13.539	13.494	EPSD	ICGC;COSMIC	9.540	Down-regulation
Atypical_PIKK_ATM_ATM_ST	Q12888	TP53BP1	Q13315	ATM	T543	E541K	541	Missense	proximal	-2	no	13.539	12.963	EPSD	ICGC	9.540	Down-regulation
Atypical_PIKK_ATM_ATM_ST	Q12888	TP53BP1	Q13315	ATM	T548	P550H	550	Missense	proximal	2	no	10.427	10.200	EPSD	ICGC;COSMIC	9.540	Down-regulation
Atypical_PIKK_ATM_ATM_ST	Q12888	TP53BP1	Q13315	ATM	T548	T548M	548	Missense	central	0	yes	10.427	0.000	EPSD	ICGC;COSMIC	9.540	Loss
Atypical_PIKK_ATM_ATM_ST	Q12888	TP53BP1	Q13315	ATM	T548	M551L	551	Missense	distal	3	no	10.427	10.453	EPSD	ICGC;COSMIC	9.540	Up-regulation
Atypical_PIKK_ATM_ATM_ST	Q12888	TP53BP1	Q13315	ATM	T548	N542I	542	Missense	distal	-6	no	10.427	10.142	EPSD	ICGC;COSMIC	9.540	Down-regulation
Atypical_PIKK_ATM_ATM_ST	Q12888	TP53BP1	Q13315	ATM	T548	E546D	546	Missense	proximal	-2	no	10.427	9.948	EPSD	ICGC;COSMIC	9.540	Down-regulation
Atypical_PIKK_ATM_ATM_ST	Q12888	TP53BP1	Q13315	ATM	T548	P550S	550	Missense	proximal	2	no	10.427	10.882	EPSD	ICGC;COSMIC	9.540	Up-regulation
Atypical_PIKK_ATM_ATM_ST	Q12888	TP53BP1	Q13315	ATM	T548	E549K	549	Missense	proximal	1	no	10.427	9.475	EPSD	ICGC;COSMIC	9.540	Loss
Atypical_PIKK_ATM_ATM_ST	Q12888	TP53BP1	Q13315	ATM	T548	L555V	555	Missense	distal	7	no	10.427	10.456	EPSD	ICGC;COSMIC	9.540	Up-regulation
Atypical_PIKK_ATM_ATM_ST	Q12888	TP53BP1	Q13315	ATM	T548	E541K	541	Missense	distal	-7	no	10.427	9.759	EPSD	ICGC	9.540	Down-regulation
Atypical_PIKK_ATM_ATM_ST	Q12888	TP53BP1	Q13315	ATM	S580	Q573H	573	Missense	distal	-7	no	16.217	16.102	EPSD	ICGC;COSMIC	9.540	Down-regulation
Atypical_PIKK_ATM_ATM_ST	Q12888	TP53BP1	Q13315	ATM	S580	G575C	575	Missense	distal	-5	no	16.217	16.255	EPSD	ICGC;COSMIC	9.540	Up-regulation
Atypical_PIKK_ATM_ATM_ST	Q12888	TP53BP1	Q13315	ATM	S580	D583Y	583	Missense	distal	3	no	16.217	16.275	EPSD	ICGC	9.540	Up-regulation
Atypical_PIKK_ATM_ATM_ST	Q12888	TP53BP1	Q13315	ATM	S625	P629L	629	Missense	distal	4	no	13.767	13.986	EPSD	ICGC;COSMIC	9.540	Up-regulation
Atypical_PIKK_ATM_ATM_ST	Q12888	TP53BP1	Q13315	ATM	S630	S635F	635	Missense	distal	5	no	10.478	10.784	EPSD	ICGC;COSMIC	9.540	Up-regulation
Atypical_PIKK_ATM_ATM_ST	Q12888	TP53BP1	Q13315	ATM	S630	P629L	629	Missense	proximal	-1	no	10.478	10.635	EPSD	ICGC;COSMIC	9.540	Up-regulation
Atypical_PIKK_ATM_ATM_ST	Q12888	TP53BP1	Q13315	ATM	S630	R634Q	634	Missense	distal	4	no	10.478	10.330	EPSD	ICGC;COSMIC	9.540	Down-regulation
Atypical_PIKK_ATM_ATM_ST	Q12888	TP53BP1	Q13315	ATM	T633	R634Q	634	Missense	proximal	1	no	5.293	11.945	EPSD	ICGC;COSMIC	9.540	Gain
Atypical_PIKK_ATM_ATM_ST	Q12888	TP53BP1	Q13315	ATM	S674	G676A	676	Missense	proximal	2	no	13.372	13.648	EPSD	ICGC;COSMIC	9.540	Up-regulation
Atypical_PIKK_ATM_ATM_ST	Q12888	TP53BP1	Q13315	ATM	S674	P668S	668	Missense	distal	-6	no	13.372	13.431	EPSD	ICGC;COSMIC	9.540	Up-regulation
Atypical_PIKK_ATM_ATM_ST	Q12888	TP53BP1	Q13315	ATM	S674	I667F	667	Missense	distal	-7	no	13.372	13.207	EPSD	ICGC;COSMIC	9.540	Down-regulation
Atypical_PIKK_ATM_ATM_ST	Q12888	TP53BP1	Q13315	ATM	S674	L679H	679	Missense	distal	5	no	13.372	13.348	EPSD	ICGC;COSMIC	9.540	Down-regulation
Atypical_PIKK_ATM_ATM_ST	Q12888	TP53BP1	Q13315	ATM	S674	L679P	679	Missense	distal	5	no	13.372	13.389	EPSD	ICGC;COSMIC	9.540	Up-regulation
Atypical_PIKK_ATM_ATM_ST	Q12888	TP53BP1	Q13315	ATM	S727	Q729E	729	Missense	proximal	2	no	12.288	13.101	EPSD	ICGC;COSMIC	9.540	Up-regulation
Atypical_PIKK_ATM_ATM_ST	Q12888	TP53BP1	Q13315	ATM	S727	I733T	733	Missense	distal	6	no	12.288	12.319	EPSD	ICGC;COSMIC	9.540	Up-regulation
Atypical_PIKK_ATM_ATM_ST	Q12888	TP53BP1	Q13315	ATM	S751	S755I	755	Missense	distal	4	no	9.862	10.525	EPSD	ICGC;COSMIC	9.540	Up-regulation
Atypical_PIKK_ATM_ATM_ST	Q12888	TP53BP1	Q13315	ATM	S751	S755R	755	Missense	distal	4	no	9.862	10.044	EPSD	ICGC	9.540	Up-regulation
Atypical_PIKK_ATM_ATM_ST	Q12888	TP53BP1	Q13315	ATM	S751	S754F	754	Missense	distal	3	no	9.862	10.444	EPSD	ICGC;COSMIC	9.540	Up-regulation
Atypical_PIKK_ATM_ATM_ST	Q12888	TP53BP1	Q13315	ATM	S831	S831L	831	Missense	central	0	yes	15.548	0.000	EPSD	ICGC;COSMIC	9.540	Loss
Atypical_PIKK_ATM_ATM_ST	Q12888	TP53BP1	Q13315	ATM	S831	Q832K	832	Missense	proximal	1	no	15.548	8.699	EPSD	ICGC	9.540	Loss
Atypical_PIKK_ATM_ATM_ST	Q12888	TP53BP1	Q13315	ATM	S831	S834F	834	Missense	distal	3	no	15.548	16.130	EPSD	ICGC;COSMIC	9.540	Up-regulation
Atypical_PIKK_ATM_ATM_ST	Q12888	TP53BP1	Q13315	ATM	T855	P853T	853	Missense	proximal	-2	no	12.701	12.850	EPSD	ICGC	9.540	Up-regulation
Atypical_PIKK_ATM_ATM_ST	Q12888	TP53BP1	Q13315	ATM	T855	T855I	855	Missense	central	0	yes	12.701	0.000	EPSD	ICGC;COSMIC	9.540	Loss
Atypical_PIKK_ATM_ATM_ST	Q12888	TP53BP1	Q13315	ATM	T855	Q854H	854	Missense	proximal	-1	no	12.701	12.564	EPSD	ICGC;COSMIC	9.540	Down-regulation
Atypical_PIKK_ATM_ATM_ST	Q12888	TP53BP1	Q13315	ATM	S892	S888C	888	Missense	distal	-4	no	13.741	12.168	EPSD	ICGC;COSMIC	9.540	Down-regulation
Atypical_PIKK_ATM_ATM_ST	Q12888	TP53BP1	Q13315	ATM	S970	G976R	976	Missense	distal	6	no	11.215	11.217	EPSD	ICGC;COSMIC	9.540	Up-regulation
Atypical_PIKK_ATM_ATM_ST	Q12888	TP53BP1	Q13315	ATM	S970	S975Y	975	Missense	distal	5	no	11.215	11.280	EPSD	ICGC	9.540	Up-regulation
Atypical_PIKK_ATM_ATM_ST	Q12888	TP53BP1	Q13315	ATM	S970	P966T	966	Missense	distal	-4	no	11.215	11.502	EPSD	ICGC;COSMIC	9.540	Up-regulation
Atypical_PIKK_ATM_ATM_ST	Q12888	TP53BP1	Q13315	ATM	S970	K972N	972	Missense	proximal	2	no	11.215	11.394	EPSD	ICGC;COSMIC	9.540	Up-regulation
Atypical_PIKK_ATM_ATM_ST	Q12888	TP53BP1	Q13315	ATM	S970	G971E	971	Missense	proximal	1	no	11.215	11.793	EPSD	ICGC;COSMIC	9.540	Up-regulation
Atypical_PIKK_ATM_ATM_ST	Q12888	TP53BP1	Q13315	ATM	S970	G976W	976	Missense	distal	6	no	11.215	11.185	EPSD	ICGC;COSMIC	9.540	Down-regulation
Atypical_PIKK_ATM_ATM_ST	Q12888	TP53BP1	Q13315	ATM	S999	E1000Q	1000	Missense	proximal	1	no	8.260	14.157	EPSD	ICGC;GDSC	9.540	Gain
Atypical_PIKK_ATM_ATM_ST	Q12888	TP53BP1	Q13315	ATM	S1028	A1027S	1027	Missense	proximal	-1	no	10.733	10.893	EPSD	ICGC;COSMIC	9.540	Up-regulation
Atypical_PIKK_ATM_ATM_ST	Q12888	TP53BP1	Q13315	ATM	S1068	E1075Q	1075	Missense	distal	7	no	13.473	13.488	EPSD	ICGC;COSMIC	9.540	Up-regulation
Atypical_PIKK_ATM_ATM_ST	Q12888	TP53BP1	Q13315	ATM	S1068	E1073D	1073	Missense	distal	5	no	13.473	13.731	EPSD	ICGC;COSMIC	9.540	Up-regulation
Atypical_PIKK_ATM_ATM_ST	Q12888	TP53BP1	Q13315	ATM	S1068	P1066Q	1066	Missense	proximal	-2	no	13.473	13.586	EPSD	ICGC;COSMIC	9.540	Up-regulation
Atypical_PIKK_ATM_ATM_ST	Q12888	TP53BP1	Q13315	ATM	S1086	I1093F	1093	Missense	distal	7	no	14.251	14.279	EPSD	ICGC;COSMIC	9.540	Up-regulation
Atypical_PIKK_ATM_ATM_ST	Q12888	TP53BP1	Q13315	ATM	S1086	D1080E	1080	Missense	distal	-6	no	14.251	14.465	EPSD	ICGC	9.540	Up-regulation
Atypical_PIKK_ATM_ATM_ST	Q12888	TP53BP1	Q13315	ATM	S1086	Q1085K	1085	Missense	proximal	-1	no	14.251	14.125	EPSD	ICGC	9.540	Down-regulation
Atypical_PIKK_ATM_ATM_ST	Q12888	TP53BP1	Q13315	ATM	S1086	G1079C	1079	Missense	distal	-7	no	14.251	14.090	EPSD	ICGC;COSMIC	9.540	Down-regulation
Atypical_PIKK_ATM_ATM_ST	Q12888	TP53BP1	Q13315	ATM	S1104	I1109T	1109	Missense	distal	5	no	13.840	13.613	EPSD	ICGC;COSMIC	9.540	Down-regulation
Atypical_PIKK_ATM_ATM_ST	Q12888	TP53BP1	Q13315	ATM	S1104	S1101Y	1101	Missense	distal	-3	no	13.840	13.972	EPSD	ICGC;COSMIC	9.540	Up-regulation
Atypical_PIKK_ATM_ATM_ST	Q12888	TP53BP1	Q13315	ATM	S1148	E1145K	1145	Missense	distal	-3	no	16.532	16.600	EPSD	ICGC;COSMIC	9.540	Up-regulation
Atypical_PIKK_ATM_ATM_ST	Q12888	TP53BP1	Q13315	ATM	S1148	G1153V	1153	Missense	distal	5	no	16.532	16.566	EPSD	ICGC;COSMIC	9.540	Up-regulation
Atypical_PIKK_ATM_ATM_ST	Q12888	TP53BP1	Q13315	ATM	T1171	E1165K	1165	Missense	distal	-6	no	13.352	13.051	EPSD	ICGC;COSMIC	9.540	Down-regulation
Atypical_PIKK_ATM_ATM_ST	Q12888	TP53BP1	Q13315	ATM	T1171	I1174V	1174	Missense	distal	3	no	13.352	13.194	EPSD	ICGC;COSMIC	9.540	Down-regulation
Atypical_PIKK_ATM_ATM_ST	Q12888	TP53BP1	Q13315	ATM	S1216	G1211W	1211	Missense	distal	-5	no	11.177	11.364	EPSD	ICGC;COSMIC	9.540	Up-regulation
Atypical_PIKK_ATM_ATM_ST	Q12888	TP53BP1	Q13315	ATM	S1216	A1209V	1209	Missense	distal	-7	no	11.177	10.794	EPSD	ICGC;COSMIC	9.540	Down-regulation
Atypical_PIKK_ATM_ATM_ST	Q12888	TP53BP1	Q13315	ATM	T1273	R1267I	1267	Missense	distal	-6	no	9.816	9.596	EPSD	ICGC;COSMIC	9.540	Down-regulation
Atypical_PIKK_ATM_ATM_ST	Q12888	TP53BP1	Q13315	ATM	T1273	E1266K	1266	Missense	distal	-7	no	9.816	9.148	EPSD	ICGC;COSMIC	9.540	Loss
Atypical_PIKK_ATM_ATM_ST	Q12888	TP53BP1	Q13315	ATM	S1288	C1283R	1283	Missense	distal	-5	no	11.610	11.593	EPSD	ICGC;COSMIC	9.540	Down-regulation
Atypical_PIKK_ATM_ATM_ST	Q12888	TP53BP1	Q13315	ATM	S1290	C1283R	1283	Missense	distal	-7	no	17.431	17.706	EPSD	ICGC;COSMIC	9.540	Up-regulation
Atypical_PIKK_ATM_ATM_ST	Q12888	TP53BP1	Q13315	ATM	S1317	L1321F	1321	Missense	distal	4	no	10.076	10.562	EPSD	ICGC;COSMIC	9.540	Up-regulation
Atypical_PIKK_ATM_ATM_ST	Q12888	TP53BP1	Q13315	ATM	S1317	S1310P	1310	Missense	distal	-7	no	10.076	9.840	EPSD	ICGC;COSMIC	9.540	Down-regulation
Atypical_PIKK_ATM_ATM_ST	Q12888	TP53BP1	Q13315	ATM	S1317	L1321I	1321	Missense	distal	4	no	10.076	10.397	EPSD	ICGC;COSMIC	9.540	Up-regulation
Atypical_PIKK_ATM_ATM_ST	Q12888	TP53BP1	Q13315	ATM	S1317	G1318R	1318	Missense	proximal	1	no	10.076	9.898	EPSD	ICGC;COSMIC	9.540	Down-regulation
Atypical_PIKK_ATM_ATM_ST	Q12888	TP53BP1	Q13315	ATM	S1320	S1326N	1326	Missense	distal	6	no	10.039	10.029	EPSD	ICGC;COSMIC	9.540	Down-regulation
Atypical_PIKK_ATM_ATM_ST	Q12888	TP53BP1	Q13315	ATM	S1320	L1321F	1321	Missense	proximal	1	no	10.039	6.159	EPSD	ICGC;COSMIC	9.540	Loss
Atypical_PIKK_ATM_ATM_ST	Q12888	TP53BP1	Q13315	ATM	S1320	L1321I	1321	Missense	proximal	1	no	10.039	-0.330	EPSD	ICGC;COSMIC	9.540	Loss
Atypical_PIKK_ATM_ATM_ST	Q12888	TP53BP1	Q13315	ATM	S1368	T1372M	1372	Missense	distal	4	no	14.035	14.208	EPSD	ICGC;COSMIC	9.540	Up-regulation
Atypical_PIKK_ATM_ATM_ST	Q12888	TP53BP1	Q13315	ATM	S1368	T1370K	1370	Missense	proximal	2	no	14.035	13.477	EPSD	ICGC;COSMIC	9.540	Down-regulation
Atypical_PIKK_ATM_ATM_ST	Q12888	TP53BP1	Q13315	ATM	S1430	S1430P	1430	Missense	central	0	yes	10.427	0.000	EPSD	ICGC;COSMIC	9.540	Loss
Atypical_PIKK_ATM_ATM_ST	Q12888	TP53BP1	Q13315	ATM	S1430	D1424E	1424	Missense	distal	-6	no	10.427	10.641	EPSD	ICGC	9.540	Up-regulation
Atypical_PIKK_ATM_ATM_ST	Q12888	TP53BP1	Q13315	ATM	S1430	D1432N	1432	Missense	proximal	2	no	10.427	9.405	EPSD	ICGC;COSMIC	9.540	Loss
Atypical_PIKK_ATM_ATM_ST	Q12888	TP53BP1	Q13315	ATM	S1462	G1455D	1455	Missense	distal	-7	no	11.998	12.289	EPSD	ICGC;COSMIC	9.540	Up-regulation
Atypical_PIKK_ATM_ATM_ST	Q12888	TP53BP1	Q13315	ATM	S1462	R1458C	1458	Missense	distal	-4	no	11.998	11.236	EPSD	ICGC;COSMIC	9.540	Down-regulation
Atypical_PIKK_ATM_ATM_ST	Q12888	TP53BP1	Q13315	ATM	S1462	P1466S	1466	Missense	distal	4	no	11.998	11.876	EPSD	ICGC;COSMIC	9.540	Down-regulation
Atypical_PIKK_ATM_ATM_ST	Q12888	TP53BP1	Q13315	ATM	S1462	R1459H	1459	Missense	distal	-3	no	11.998	11.353	EPSD	ICGC;COSMIC	9.540	Down-regulation
Atypical_PIKK_ATM_ATM_ST	Q12888	TP53BP1	Q13315	ATM	S1481	V1487I	1487	Missense	distal	6	no	10.215	10.198	EPSD	ICGC;COSMIC	9.540	Down-regulation
Atypical_PIKK_ATM_ATM_ST	Q12888	TP53BP1	Q13315	ATM	S1481	G1483V	1483	Missense	proximal	2	no	10.215	10.181	EPSD	ICGC	9.540	Down-regulation
Atypical_PIKK_ATM_ATM_ST	Q12888	TP53BP1	Q13315	ATM	S1635	P1636S	1636	Missense	proximal	1	no	9.886	2.910	EPSD	ICGC;COSMIC	9.540	Loss
Atypical_PIKK_ATM_ATM_ST	Q12888	TP53BP1	Q13315	ATM	S1635	A1641T	1641	Missense	distal	6	no	9.886	9.869	EPSD	ICGC;COSMIC	9.540	Down-regulation
Atypical_PIKK_ATM_ATM_ST	Q12888	TP53BP1	Q13315	ATM	T1648	S1644N	1644	Missense	distal	-4	no	9.890	8.961	EPSD	ICGC;COSMIC	9.540	Loss
Atypical_PIKK_ATM_ATM_ST	Q12888	TP53BP1	Q13315	ATM	T1648	A1641T	1641	Missense	distal	-7	no	9.890	9.905	EPSD	ICGC;COSMIC	9.540	Up-regulation
Atypical_PIKK_ATM_ATM_ST	Q12888	TP53BP1	Q13315	ATM	S1656	V1663I	1663	Missense	distal	7	no	10.215	10.198	EPSD	ICGC;COSMIC	9.540	Down-regulation
Atypical_PIKK_ATM_ATM_ST	Q12888	TP53BP1	Q13315	ATM	S1656	P1657L	1657	Missense	proximal	1	no	10.215	8.660	EPSD	ICGC;COSMIC	9.540	Loss
Atypical_PIKK_ATM_ATM_ST	Q12888	TP53BP1	Q13315	ATM	S1673	R1668I	1668	Missense	distal	-5	no	10.010	10.048	EPSD	ICGC;COSMIC	9.540	Up-regulation
Atypical_PIKK_ATM_ATM_ST	Q12888	TP53BP1	Q13315	ATM	S1673	E1676K	1676	Missense	distal	3	no	10.010	10.299	EPSD	ICGC;COSMIC	9.540	Up-regulation
Atypical_PIKK_ATM_ATM_ST	Q12888	TP53BP1	Q13315	ATM	S1673	R1677W	1677	Missense	distal	4	no	10.010	10.154	EPSD	ICGC;COSMIC	9.540	Up-regulation
Atypical_PIKK_ATM_ATM_ST	Q12888	TP53BP1	Q13315	ATM	S1673	R1677Q	1677	Missense	distal	4	no	10.010	9.861	EPSD	ICGC;COSMIC	9.540	Down-regulation
Atypical_PIKK_ATM_ATM_ST	Q12888	TP53BP1	Q13315	ATM	S1678	R1684H	1684	Missense	distal	6	no	11.099	11.084	EPSD	ICGC;COSMIC	9.540	Down-regulation
Atypical_PIKK_ATM_ATM_ST	Q12888	TP53BP1	Q13315	ATM	S1678	E1676K	1676	Missense	proximal	-2	no	11.099	10.523	EPSD	ICGC;COSMIC	9.540	Down-regulation
Atypical_PIKK_ATM_ATM_ST	Q12888	TP53BP1	Q13315	ATM	S1678	R1684C	1684	Missense	distal	6	no	11.099	11.045	EPSD	ICGC;COSMIC	9.540	Down-regulation
Atypical_PIKK_ATM_ATM_ST	Q12888	TP53BP1	Q13315	ATM	S1678	R1677W	1677	Missense	proximal	-1	no	11.099	11.096	EPSD	ICGC;COSMIC	9.540	Down-regulation
Atypical_PIKK_ATM_ATM_ST	Q12888	TP53BP1	Q13315	ATM	S1678	R1677Q	1677	Missense	proximal	-1	no	11.099	11.407	EPSD	ICGC;COSMIC	9.540	Up-regulation
Atypical_PIKK_ATM_ATM_ST	Q12888	TP53BP1	Q13315	ATM	S1778	G1783A	1783	Missense	distal	5	no	12.854	12.724	EPSD;PhosphoSitePlus	ICGC;COSMIC	9.540	Down-regulation
Atypical_PIKK_ATM_ATM_ST	Q12888	TP53BP1	Q13315	ATM	S1778	R1781Q	1781	Missense	distal	3	no	12.854	12.752	EPSD;PhosphoSitePlus	ICGC;COSMIC	9.540	Down-regulation
Atypical_PIKK_ATM_ATM_ST	Q12888	TP53BP1	Q13315	ATM	S1778	F1771L	1771	Missense	distal	-7	no	12.854	13.096	EPSD;PhosphoSitePlus	ICGC;COSMIC	9.540	Up-regulation
Atypical_PIKK_ATM_ATM_ST	Q12888	TP53BP1	Q13315	ATM	S1778	F1771Y	1771	Missense	distal	-7	no	12.854	13.389	EPSD;PhosphoSitePlus	ICGC;COSMIC	9.540	Up-regulation
Atypical_PIKK_ATM_ATM_ST	P08047	SP1	Q13315	ATM	S36	S36L	36	Missense	central	0	yes	13.702	0.000	EPSD	ICGC;COSMIC	9.540	Loss
Atypical_PIKK_ATM_ATM_ST	P08047	SP1	Q13315	ATM	S36	F35L	35	Missense	proximal	-1	no	13.702	13.994	EPSD	ICGC;COSMIC	9.540	Up-regulation
Atypical_PIKK_ATM_ATM_ST	P08047	SP1	Q13315	ATM	S56	S56A	56	Missense	central	0	yes	15.449	0.000	PhosphoSitePlus;EPSD	ICGC;COSMIC	9.540	Loss
Atypical_PIKK_ATM_ATM_ST	P08047	SP1	Q13315	ATM	T98	N105S	105	Missense	distal	7	no	13.316	13.301	EPSD	ICGC;COSMIC	9.540	Down-regulation
Atypical_PIKK_ATM_ATM_ST	P08047	SP1	Q13315	ATM	T98	G103D	103	Missense	distal	5	no	13.316	13.224	EPSD	ICGC;COSMIC	9.540	Down-regulation
Atypical_PIKK_ATM_ATM_ST	P08047	SP1	Q13315	ATM	S101	N105S	105	Missense	distal	4	no	12.851	12.724	EPSD;PhosphoSitePlus	ICGC;COSMIC	9.540	Down-regulation
Atypical_PIKK_ATM_ATM_ST	P08047	SP1	Q13315	ATM	S101	G103D	103	Missense	proximal	2	no	12.851	14.090	EPSD;PhosphoSitePlus	ICGC;COSMIC	9.540	Up-regulation
Atypical_PIKK_ATM_ATM_ST	P08047	SP1	Q13315	ATM	S588	Q594E	594	Missense	distal	6	no	10.857	10.904	EPSD	ICGC;COSMIC	9.540	Up-regulation
Atypical_PIKK_ATM_ATM_ST	P08047	SP1	Q13315	ATM	S588	Q592H	592	Missense	distal	4	no	10.857	10.941	EPSD	ICGC	9.540	Up-regulation
Atypical_PIKK_ATM_ATM_ST	P08047	SP1	Q13315	ATM	S588	P589Q	589	Missense	proximal	1	no	10.857	15.659	EPSD	ICGC;COSMIC	9.540	Up-regulation
Atypical_PIKK_ATM_ATM_ST	P08047	SP1	Q13315	ATM	S617	D611Y	611	Missense	distal	-6	no	9.931	9.708	EPSD	ICGC	9.540	Down-regulation
Atypical_PIKK_ATM_ATM_ST	P08047	SP1	Q13315	ATM	S617	G616V	616	Missense	proximal	-1	no	9.931	9.699	EPSD	ICGC	9.540	Down-regulation
Atypical_PIKK_ATM_ATM_ST	P08047	SP1	Q13315	ATM	S617	R615M	615	Missense	proximal	-2	no	9.931	9.935	EPSD	ICGC;COSMIC	9.540	Up-regulation
Atypical_PIKK_ATM_ATM_ST	P08047	SP1	Q13315	ATM	T739	A738G	738	Missense	proximal	-1	no	9.655	9.624	EPSD	ICGC;COSMIC	9.540	Down-regulation
Atypical_PIKK_ATM_ATM_ST	O95071	UBR5	Q13315	ATM	S117	R122K	122	Missense	distal	5	no	9.782	9.620	EPSD	ICGC;COSMIC	9.540	Down-regulation
Atypical_PIKK_ATM_ATM_ST	O95071	UBR5	Q13315	ATM	S117	T119N	119	Missense	proximal	2	no	9.782	9.402	EPSD	ICGC	9.540	Loss
Atypical_PIKK_ATM_ATM_ST	O95071	UBR5	Q13315	ATM	S117	A124E	124	Missense	distal	7	no	9.782	9.747	EPSD	ICGC	9.540	Down-regulation
Atypical_PIKK_ATM_ATM_ST	O95071	UBR5	Q13315	ATM	S117	G116V	116	Missense	proximal	-1	no	9.782	9.550	EPSD	ICGC;COSMIC	9.540	Down-regulation
Atypical_PIKK_ATM_ATM_ST	O95071	UBR5	Q13315	ATM	T158	R159Q	159	Missense	proximal	1	no	6.065	12.716	EPSD	ICGC;COSMIC;CCLE	9.540	Gain
Atypical_PIKK_ATM_ATM_ST	O95071	UBR5	Q13315	ATM	S174	V179I	179	Missense	distal	5	no	14.833	14.831	EPSD;PhosphoSitePlus	ICGC;COSMIC	9.540	Down-regulation
Atypical_PIKK_ATM_ATM_ST	O95071	UBR5	Q13315	ATM	S174	P181T	181	Missense	distal	7	no	14.833	14.831	EPSD;PhosphoSitePlus	ICGC	9.540	Down-regulation
Atypical_PIKK_ATM_ATM_ST	O95071	UBR5	Q13315	ATM	S174	P181Q	181	Missense	distal	7	no	14.833	14.824	EPSD;PhosphoSitePlus	ICGC	9.540	Down-regulation
Atypical_PIKK_ATM_ATM_ST	O95071	UBR5	Q13315	ATM	S191	Q198E	198	Missense	distal	7	no	14.811	14.797	PhosphoSitePlus;EPSD	ICGC;COSMIC	9.540	Down-regulation
Atypical_PIKK_ATM_ATM_ST	O95071	UBR5	Q13315	ATM	S191	V196G	196	Missense	distal	5	no	14.811	14.777	PhosphoSitePlus;EPSD	ICGC	9.540	Down-regulation
Atypical_PIKK_ATM_ATM_ST	O95071	UBR5	Q13315	ATM	S352	D359H	359	Missense	distal	7	no	10.872	10.892	EPSD	ICGC;COSMIC	9.540	Up-regulation
Atypical_PIKK_ATM_ATM_ST	O95071	UBR5	Q13315	ATM	S352	D359G	359	Missense	distal	7	no	10.872	10.905	EPSD	ICGC;COSMIC	9.540	Up-regulation
Atypical_PIKK_ATM_ATM_ST	O95071	UBR5	Q13315	ATM	S612	A614T	614	Missense	proximal	2	no	10.640	10.961	EPSD	ICGC;COSMIC;CCLE	9.540	Up-regulation
Atypical_PIKK_ATM_ATM_ST	O95071	UBR5	Q13315	ATM	S612	A614S	614	Missense	proximal	2	no	10.640	11.223	EPSD	ICGC;COSMIC	9.540	Up-regulation
Atypical_PIKK_ATM_ATM_ST	O95071	UBR5	Q13315	ATM	S1308	T1306K	1306	Missense	proximal	-2	no	11.601	11.294	EPSD	ICGC	9.540	Down-regulation
Atypical_PIKK_ATM_ATM_ST	O95071	UBR5	Q13315	ATM	S1347	M1344V	1344	Missense	distal	-3	no	13.700	13.763	EPSD	ICGC;COSMIC	9.540	Up-regulation
Atypical_PIKK_ATM_ATM_ST	O95071	UBR5	Q13315	ATM	S1347	P1353H	1353	Missense	distal	6	no	13.700	13.677	EPSD	ICGC;COSMIC	9.540	Down-regulation
Atypical_PIKK_ATM_ATM_ST	O95071	UBR5	Q13315	ATM	S1549	Q1544K	1544	Missense	distal	-5	no	16.098	16.148	EPSD	ICGC;COSMIC	9.540	Up-regulation
Atypical_PIKK_ATM_ATM_ST	O95071	UBR5	Q13315	ATM	S1551	Q1544K	1544	Missense	distal	-7	no	14.645	14.532	EPSD	ICGC;COSMIC	9.540	Down-regulation
Atypical_PIKK_ATM_ATM_ST	O95071	UBR5	Q13315	ATM	S2241	R2246W	2246	Missense	distal	5	no	11.674	11.698	EPSD	ICGC;COSMIC;GDSC;CCLE	9.540	Up-regulation
Atypical_PIKK_ATM_ATM_ST	O95071	UBR5	Q13315	ATM	T2270	P2271Q	2271	Missense	proximal	1	no	7.733	12.535	EPSD	ICGC;COSMIC	9.540	Gain
Atypical_PIKK_ATM_ATM_ST	O95071	UBR5	Q13315	ATM	S2356	R2360L	2360	Missense	distal	4	no	9.380	9.540	EPSD	ICGC;COSMIC	9.540	Gain
Atypical_PIKK_ATM_ATM_ST	O95071	UBR5	Q13315	ATM	S2384	P2389H	2389	Missense	distal	5	no	11.328	11.286	EPSD	ICGC	9.540	Down-regulation
Atypical_PIKK_ATM_ATM_ST	O95071	UBR5	Q13315	ATM	S2384	G2381V	2381	Missense	distal	-3	no	11.328	11.468	EPSD	ICGC;COSMIC	9.540	Up-regulation
Atypical_PIKK_ATM_ATM_ST	O95071	UBR5	Q13315	ATM	S2586	A2585T	2585	Missense	proximal	-1	no	14.138	14.309	EPSD;PhosphoSitePlus	ICGC;COSMIC;GDSC	9.540	Up-regulation
Atypical_PIKK_ATM_ATM_ST	Q92945	KHSRP	Q13315	ATM	S125	Q126K	126	Missense	proximal	1	no	13.930	7.082	EPSD	ICGC;COSMIC	9.540	Loss
Atypical_PIKK_ATM_ATM_ST	Q92945	KHSRP	Q13315	ATM	S132	Q126K	126	Missense	distal	-6	no	14.247	14.171	EPSD	ICGC;COSMIC	9.540	Down-regulation
Atypical_PIKK_ATM_ATM_ST	Q92945	KHSRP	Q13315	ATM	S132	L134R	134	Missense	proximal	2	no	14.247	14.493	EPSD	ICGC;COSMIC	9.540	Up-regulation
Atypical_PIKK_ATM_ATM_ST	Q92945	KHSRP	Q13315	ATM	S181	G175A	175	Missense	distal	-6	no	10.909	11.090	EPSD	ICGC	9.540	Up-regulation
Atypical_PIKK_ATM_ATM_ST	Q92945	KHSRP	Q13315	ATM	S181	P182Q	182	Missense	proximal	1	no	10.909	15.710	EPSD	ICGC;COSMIC	9.540	Up-regulation
Atypical_PIKK_ATM_ATM_ST	Q92945	KHSRP	Q13315	ATM	S480	R478L	478	Missense	proximal	-2	no	9.489	9.543	EPSD	ICGC;COSMIC	9.540	Gain
Atypical_PIKK_ATM_ATM_ST	Q92945	KHSRP	Q13315	ATM	S670	P668A	668	Missense	proximal	-2	no	15.038	15.087	PhosphoSitePlus;EPSD	ICGC;COSMIC	9.540	Up-regulation
Atypical_PIKK_ATM_ATM_ST	Q96S59	RANBP9	Q13315	ATM	S170	Y177D	177	Missense	distal	7	no	10.265	10.239	EPSD	ICGC	9.540	Down-regulation
Atypical_PIKK_ATM_ATM_ST	Q96S59	RANBP9	Q13315	ATM	S170	W169R	169	Missense	proximal	-1	no	10.265	10.268	EPSD	ICGC;COSMIC	9.540	Up-regulation
Atypical_PIKK_ATM_ATM_ST	Q96S59	RANBP9	Q13315	ATM	S181	Y177D	177	Missense	distal	-4	no	13.194	14.290	EPSD;PhosphoSitePlus	ICGC	9.540	Up-regulation
Atypical_PIKK_ATM_ATM_ST	Q96S59	RANBP9	Q13315	ATM	S487	S483C	483	Missense	distal	-4	no	11.402	9.829	EPSD	ICGC	9.540	Down-regulation
Atypical_PIKK_ATM_ATM_ST	Q96S59	RANBP9	Q13315	ATM	S550	S548L	548	Missense	proximal	-2	no	14.458	14.068	EPSD;PhosphoSitePlus	ICGC;COSMIC	9.540	Down-regulation
Atypical_PIKK_ATM_ATM_ST	Q96S59	RANBP9	Q13315	ATM	S550	I545V	545	Missense	distal	-5	no	14.458	14.456	EPSD;PhosphoSitePlus	ICGC;COSMIC	9.540	Down-regulation
Atypical_PIKK_ATM_ATM_ST	Q96S59	RANBP9	Q13315	ATM	S613	A616S	616	Missense	distal	3	no	12.326	12.271	EPSD	ICGC	9.540	Down-regulation
Atypical_PIKK_ATM_ATM_ST	Q92547	TOPBP1	Q13315	ATM	S301	N304K	304	Missense	distal	3	no	16.182	16.095	EPSD	ICGC	9.540	Down-regulation
Atypical_PIKK_ATM_ATM_ST	Q92547	TOPBP1	Q13315	ATM	S301	T300N	300	Missense	proximal	-1	no	16.182	16.117	EPSD	ICGC	9.540	Down-regulation
Atypical_PIKK_ATM_ATM_ST	Q92547	TOPBP1	Q13315	ATM	S301	P299H	299	Missense	proximal	-2	no	16.182	15.991	EPSD	ICGC	9.540	Down-regulation
Atypical_PIKK_ATM_ATM_ST	Q92547	TOPBP1	Q13315	ATM	S492	S499C	499	Missense	distal	7	no	16.145	16.197	EPSD;PhosphoSitePlus	ICGC;COSMIC	9.540	Up-regulation
Atypical_PIKK_ATM_ATM_ST	Q92547	TOPBP1	Q13315	ATM	S492	S499P	499	Missense	distal	7	no	16.145	16.163	EPSD;PhosphoSitePlus	ICGC	9.540	Up-regulation
Atypical_PIKK_ATM_ATM_ST	Q92547	TOPBP1	Q13315	ATM	S554	Q555K	555	Missense	proximal	1	no	15.307	8.459	EPSD;PhosphoSitePlus	ICGC	9.540	Loss
Atypical_PIKK_ATM_ATM_ST	Q92547	TOPBP1	Q13315	ATM	S747	E745K	745	Missense	proximal	-2	no	11.372	10.796	EPSD	ICGC	9.540	Down-regulation
Atypical_PIKK_ATM_ATM_ST	Q92547	TOPBP1	Q13315	ATM	S805	Q810K	810	Missense	distal	5	no	11.277	11.228	EPSD	ICGC	9.540	Down-regulation
Atypical_PIKK_ATM_ATM_ST	Q92547	TOPBP1	Q13315	ATM	S805	A803T	803	Missense	proximal	-2	no	11.277	11.377	EPSD	ICGC;COSMIC;GDSC	9.540	Up-regulation
Atypical_PIKK_ATM_ATM_ST	Q92547	TOPBP1	Q13315	ATM	T822	S817L	817	Missense	distal	-5	no	12.251	12.273	EPSD	ICGC;COSMIC	9.540	Up-regulation
Atypical_PIKK_ATM_ATM_ST	Q92547	TOPBP1	Q13315	ATM	T822	K829N	829	Missense	distal	7	no	12.251	12.243	EPSD	ICGC	9.540	Down-regulation
Atypical_PIKK_ATM_ATM_ST	Q92547	TOPBP1	Q13315	ATM	S853	P849S	849	Missense	distal	-4	no	14.550	15.219	EPSD;PhosphoSitePlus	ICGC	9.540	Up-regulation
Atypical_PIKK_ATM_ATM_ST	Q92547	TOPBP1	Q13315	ATM	S853	S860N	860	Missense	distal	7	no	14.550	14.564	EPSD;PhosphoSitePlus	ICGC	9.540	Up-regulation
Atypical_PIKK_ATM_ATM_ST	Q92547	TOPBP1	Q13315	ATM	S864	V868I	868	Missense	distal	4	no	9.733	10.090	EPSD	ICGC	9.540	Up-regulation
Atypical_PIKK_ATM_ATM_ST	Q92547	TOPBP1	Q13315	ATM	S864	S860N	860	Missense	distal	-4	no	9.733	8.805	EPSD	ICGC	9.540	Loss
Atypical_PIKK_ATM_ATM_ST	Q92547	TOPBP1	Q13315	ATM	S864	I867M	867	Missense	distal	3	no	9.733	9.488	EPSD	ICGC;COSMIC	9.540	Loss
Atypical_PIKK_ATM_ATM_ST	Q92547	TOPBP1	Q13315	ATM	S1002	A1003T	1003	Missense	proximal	1	no	9.626	6.690	EPSD	ICGC;COSMIC	9.540	Loss
Atypical_PIKK_ATM_ATM_ST	Q92547	TOPBP1	Q13315	ATM	S1002	D1000G	1000	Missense	proximal	-2	no	9.626	9.482	EPSD	ICGC;COSMIC	9.540	Loss
Atypical_PIKK_ATM_ATM_ST	Q92547	TOPBP1	Q13315	ATM	T1062	E1069D	1069	Missense	distal	7	no	13.737	13.750	PhosphoSitePlus;EPSD	ICGC	9.540	Up-regulation
Atypical_PIKK_ATM_ATM_ST	Q92547	TOPBP1	Q13315	ATM	S1138	Q1139K	1139	Missense	proximal	1	no	13.698	6.849	EPSD;PhosphoSitePlus	ICGC	9.540	Loss
Atypical_PIKK_ATM_ATM_ST	P12956	XRCC6	Q13315	ATM	S27	K31E	31	Missense	distal	4	no	12.375	11.998	PhosphoSitePlus;EPSD	ICGC;COSMIC	9.540	Down-regulation
Atypical_PIKK_ATM_ATM_ST	P12956	XRCC6	Q13315	ATM	S27	L24I	24	Missense	distal	-3	no	12.375	12.836	PhosphoSitePlus;EPSD	ICGC;COSMIC	9.540	Up-regulation
Atypical_PIKK_ATM_ATM_ST	P12956	XRCC6	Q13315	ATM	S33	K31E	31	Missense	proximal	-2	no	12.467	13.043	EPSD;PhosphoSitePlus	ICGC;COSMIC	9.540	Up-regulation
Atypical_PIKK_ATM_ATM_ST	P12956	XRCC6	Q13315	ATM	S37	K31E	31	Missense	distal	-6	no	10.801	11.102	EPSD	ICGC;COSMIC	9.540	Up-regulation
Atypical_PIKK_ATM_ATM_ST	P12956	XRCC6	Q13315	ATM	S51	S45A	45	Missense	distal	-6	no	15.886	15.866	EPSD	ICGC	9.540	Down-regulation
Atypical_PIKK_ATM_ATM_ST	P12956	XRCC6	Q13315	ATM	S319	S324N	324	Missense	distal	5	no	12.037	12.011	EPSD	ICGC;COSMIC	9.540	Down-regulation
Atypical_PIKK_ATM_ATM_ST	P12956	XRCC6	Q13315	ATM	T334	R339W	339	Missense	distal	5	no	9.965	9.989	EPSD	ICGC;COSMIC	9.540	Up-regulation
Atypical_PIKK_ATM_ATM_ST	P12956	XRCC6	Q13315	ATM	T507	T507I	507	Missense	central	0	yes	10.243	0.000	EPSD	ICGC;COSMIC	9.540	Loss
Atypical_PIKK_ATM_ATM_ST	Q96SD1	DCLRE1C	Q13315	ATM	S503	L504V	504	Missense	proximal	1	no	12.034	5.396	PhosphoSitePlus;EPSD	ICGC;COSMIC	9.540	Loss
Atypical_PIKK_ATM_ATM_ST	Q96SD1	DCLRE1C	Q13315	ATM	S538	E545Q	545	Missense	distal	7	no	13.667	13.681	EPSD	ICGC;COSMIC	9.540	Up-regulation
Atypical_PIKK_ATM_ATM_ST	Q96SD1	DCLRE1C	Q13315	ATM	S548	E545Q	545	Missense	distal	-3	no	12.812	12.937	EPSD	ICGC;COSMIC	9.540	Up-regulation
Atypical_PIKK_ATM_ATM_ST	Q7LG56	RRM2B	Q13315	ATM	S20	R17T	17	Missense	distal	-3	no	9.872	9.064	EPSD	ICGC;COSMIC	9.540	Loss
Atypical_PIKK_ATM_ATM_ST	Q7LG56	RRM2B	Q13315	ATM	S20	D15V	15	Missense	distal	-5	no	9.872	10.196	EPSD	ICGC	9.540	Up-regulation
Atypical_PIKK_ATM_ATM_ST	Q7LG56	RRM2B	Q13315	ATM	S72	T65I	65	Missense	distal	-7	no	12.087	11.504	PhosphoSitePlus	ICGC	9.540	Down-regulation
Atypical_PIKK_ATM_ATM_ST	Q9H2K8	TAOK3	Q13315	ATM	S173	F166L	166	Missense	distal	-7	no	10.257	10.499	EPSD	ICGC;COSMIC;GDSC	9.540	Up-regulation
Atypical_PIKK_ATM_ATM_ST	Q9H2K8	TAOK3	Q13315	ATM	S173	A169D	169	Missense	distal	-4	no	10.257	10.763	EPSD	ICGC	9.540	Up-regulation
Atypical_PIKK_ATM_ATM_ST	Q9H2K8	TAOK3	Q13315	ATM	S173	G167R	167	Missense	distal	-6	no	10.257	10.279	EPSD	ICGC	9.540	Up-regulation
Atypical_PIKK_ATM_ATM_ST	Q9H2K8	TAOK3	Q13315	ATM	S173	M171T	171	Missense	proximal	-2	no	10.257	10.608	EPSD	ICGC;COSMIC	9.540	Up-regulation
Atypical_PIKK_ATM_ATM_ST	Q9H2K8	TAOK3	Q13315	ATM	T316	R317Q	317	Missense	proximal	1	no	5.417	12.068	EPSD	ICGC;COSMIC;CCLE	9.540	Gain
Atypical_PIKK_ATM_ATM_ST	Q9H2K8	TAOK3	Q13315	ATM	S324	E329D	329	Missense	distal	5	no	14.238	14.495	EPSD	ICGC;COSMIC	9.540	Up-regulation
Atypical_PIKK_ATM_ATM_ST	Q9H2K8	TAOK3	Q13315	ATM	S324	D330G	330	Missense	distal	6	no	14.238	14.241	EPSD	ICGC;COSMIC	9.540	Up-regulation
Atypical_PIKK_ATM_ATM_ST	Q9H2K8	TAOK3	Q13315	ATM	S324	R317Q	317	Missense	distal	-7	no	14.238	14.437	EPSD	ICGC;COSMIC;CCLE	9.540	Up-regulation
Atypical_PIKK_ATM_ATM_ST	Q9H2K8	TAOK3	Q13315	ATM	S324	N318K	318	Missense	distal	-6	no	14.238	14.240	EPSD	ICGC;COSMIC	9.540	Up-regulation
Atypical_PIKK_ATM_ATM_ST	Q9H2K8	TAOK3	Q13315	ATM	S336	E329D	329	Missense	distal	-7	no	10.879	10.301	EPSD	ICGC;COSMIC	9.540	Down-regulation
Atypical_PIKK_ATM_ATM_ST	Q9H2K8	TAOK3	Q13315	ATM	S336	D330G	330	Missense	distal	-6	no	10.879	10.704	EPSD	ICGC;COSMIC	9.540	Down-regulation
Atypical_PIKK_ATM_ATM_ST	Q9H2K8	TAOK3	Q13315	ATM	S336	R339K	339	Missense	distal	3	no	10.879	10.806	EPSD	ICGC	9.540	Down-regulation
Atypical_PIKK_ATM_ATM_ST	Q9H2K8	TAOK3	Q13315	ATM	S336	H333N	333	Missense	distal	-3	no	10.879	10.757	EPSD	ICGC	9.540	Down-regulation
Atypical_PIKK_ATM_ATM_ST	Q9H2K8	TAOK3	Q13315	ATM	S336	R339S	339	Missense	distal	3	no	10.879	10.693	EPSD	ICGC	9.540	Down-regulation
Atypical_PIKK_ATM_ATM_ST	Q9H2K8	TAOK3	Q13315	ATM	S359	S356R	356	Missense	distal	-3	no	15.904	16.644	PhosphoSitePlus;EPSD	ICGC;COSMIC	9.540	Up-regulation
Atypical_PIKK_ATM_ATM_ST	Q9H2K8	TAOK3	Q13315	ATM	T419	P416T	416	Missense	distal	-3	no	14.813	14.549	EPSD	ICGC;COSMIC	9.540	Down-regulation
Atypical_PIKK_ATM_ATM_ST	Q9H2K8	TAOK3	Q13315	ATM	T419	Q423K	423	Missense	distal	4	no	14.813	14.859	EPSD	ICGC	9.540	Up-regulation
Atypical_PIKK_ATM_ATM_ST	Q9H2K8	TAOK3	Q13315	ATM	S424	Q423K	423	Missense	proximal	-1	no	13.670	13.544	EPSD	ICGC	9.540	Down-regulation
Atypical_PIKK_ATM_ATM_ST	Q96RU2	USP28	Q13315	ATM	S67	E74K	74	Missense	distal	7	no	13.532	13.558	EPSD;PhosphoSitePlus	ICGC;COSMIC	9.540	Up-regulation
Atypical_PIKK_ATM_ATM_ST	Q96RU2	USP28	Q13315	ATM	S67	V71I	71	Missense	distal	4	no	13.532	13.889	EPSD;PhosphoSitePlus	ICGC	9.540	Up-regulation
Atypical_PIKK_ATM_ATM_ST	Q96RU2	USP28	Q13315	ATM	T491	S495F	495	Missense	distal	4	no	9.882	10.710	EPSD	ICGC	9.540	Up-regulation
Atypical_PIKK_ATM_ATM_ST	Q96RU2	USP28	Q13315	ATM	T491	S495A	495	Missense	distal	4	no	9.882	9.534	EPSD	ICGC;COSMIC	9.540	Loss
Atypical_PIKK_ATM_ATM_ST	Q96RU2	USP28	Q13315	ATM	S495	S495F	495	Missense	central	0	yes	15.523	0.000	PhosphoSitePlus;EPSD	ICGC	9.540	Loss
Atypical_PIKK_ATM_ATM_ST	Q96RU2	USP28	Q13315	ATM	S495	S495A	495	Missense	central	0	yes	15.523	0.000	PhosphoSitePlus;EPSD	ICGC;COSMIC	9.540	Loss
Atypical_PIKK_ATM_ATM_ST	Q96RU2	USP28	Q13315	ATM	S720	P723Q	723	Missense	distal	3	no	16.886	16.818	EPSD;PhosphoSitePlus	ICGC;COSMIC	9.540	Down-regulation
Atypical_PIKK_ATM_ATM_ST	Q96RU2	USP28	Q13315	ATM	S794	G793V	793	Missense	proximal	-1	no	10.360	10.128	EPSD	ICGC;COSMIC	9.540	Down-regulation
Atypical_PIKK_ATM_ATM_ST	Q5TZA2	CROCC	Q13315	ATM	S471	A477V	477	Missense	distal	6	no	9.820	9.790	EPSD	ICGC;COSMIC	9.540	Down-regulation
Atypical_PIKK_ATM_ATM_ST	Q5TZA2	CROCC	Q13315	ATM	S471	A477T	477	Missense	distal	6	no	9.820	9.804	EPSD	ICGC;COSMIC;GDSC;CCLE	9.540	Down-regulation
Atypical_PIKK_ATM_ATM_ST	Q5TZA2	CROCC	Q13315	ATM	S471	E465D	465	Missense	distal	-6	no	9.820	9.606	EPSD	ICGC	9.540	Down-regulation
Atypical_PIKK_ATM_ATM_ST	Q5TZA2	CROCC	Q13315	ATM	S494	R497W	497	Missense	distal	3	no	10.426	10.618	EPSD	ICGC;COSMIC	9.540	Up-regulation
Atypical_PIKK_ATM_ATM_ST	Q5TZA2	CROCC	Q13315	ATM	S494	S499F	499	Missense	distal	5	no	10.426	10.732	EPSD	ICGC	9.540	Up-regulation
Atypical_PIKK_ATM_ATM_ST	Q5TZA2	CROCC	Q13315	ATM	S494	R498H	498	Missense	distal	4	no	10.426	10.361	EPSD	ICGC	9.540	Down-regulation
Atypical_PIKK_ATM_ATM_ST	Q5TZA2	CROCC	Q13315	ATM	S494	S500P	500	Missense	distal	6	no	10.426	10.415	EPSD	ICGC;COSMIC	9.540	Down-regulation
Atypical_PIKK_ATM_ATM_ST	Q5TZA2	CROCC	Q13315	ATM	S494	L487F	487	Missense	distal	-7	no	10.426	10.184	EPSD	ICGC;COSMIC	9.540	Down-regulation
Atypical_PIKK_ATM_ATM_ST	Q5TZA2	CROCC	Q13315	ATM	S506	P511S	511	Missense	distal	5	no	10.429	10.248	EPSD	ICGC;COSMIC	9.540	Down-regulation
Atypical_PIKK_ATM_ATM_ST	Q5TZA2	CROCC	Q13315	ATM	S506	G504S	504	Missense	proximal	-2	no	10.429	10.872	EPSD	ICGC;COSMIC	9.540	Up-regulation
Atypical_PIKK_ATM_ATM_ST	Q5TZA2	CROCC	Q13315	ATM	S506	S499F	499	Missense	distal	-7	no	10.429	9.600	EPSD	ICGC	9.540	Down-regulation
Atypical_PIKK_ATM_ATM_ST	Q5TZA2	CROCC	Q13315	ATM	S506	R508S	508	Missense	proximal	2	no	10.429	11.427	EPSD	ICGC	9.540	Up-regulation
Atypical_PIKK_ATM_ATM_ST	Q5TZA2	CROCC	Q13315	ATM	S506	S500P	500	Missense	distal	-6	no	10.429	10.370	EPSD	ICGC;COSMIC	9.540	Down-regulation
Atypical_PIKK_ATM_ATM_ST	Q5TZA2	CROCC	Q13315	ATM	S512	P511S	511	Missense	proximal	-1	no	10.006	10.298	EPSD	ICGC;COSMIC	9.540	Up-regulation
Atypical_PIKK_ATM_ATM_ST	Q5TZA2	CROCC	Q13315	ATM	S512	R508S	508	Missense	distal	-4	no	10.006	10.816	EPSD	ICGC	9.540	Up-regulation
Atypical_PIKK_ATM_ATM_ST	Q5TZA2	CROCC	Q13315	ATM	S737	A732D	732	Missense	distal	-5	no	11.065	10.861	EPSD	ICGC	9.540	Down-regulation
Atypical_PIKK_ATM_ATM_ST	Q5TZA2	CROCC	Q13315	ATM	S830	R829H	829	Missense	proximal	-1	no	13.449	13.619	EPSD	ICGC;COSMIC	9.540	Up-regulation
Atypical_PIKK_ATM_ATM_ST	Q5TZA2	CROCC	Q13315	ATM	S830	E834Q	834	Missense	distal	4	no	13.449	13.780	EPSD	ICGC;COSMIC	9.540	Up-regulation
Atypical_PIKK_ATM_ATM_ST	Q5TZA2	CROCC	Q13315	ATM	S1231	R1233H	1233	Missense	proximal	2	no	9.286	9.602	EPSD	ICGC;COSMIC	9.540	Gain
Atypical_PIKK_ATM_ATM_ST	Q5TZA2	CROCC	Q13315	ATM	S1451	G1447S	1447	Missense	distal	-4	no	9.973	10.761	EPSD	ICGC;COSMIC	9.540	Up-regulation
Atypical_PIKK_ATM_ATM_ST	Q5TZA2	CROCC	Q13315	ATM	S1476	P1477L	1477	Missense	proximal	1	no	10.834	9.279	EPSD	ICGC	9.540	Loss
Atypical_PIKK_ATM_ATM_ST	Q5TZA2	CROCC	Q13315	ATM	S1483	P1477L	1477	Missense	distal	-6	no	9.755	9.525	EPSD	ICGC	9.540	Loss
Atypical_PIKK_ATM_ATM_ST	Q5TZA2	CROCC	Q13315	ATM	S1608	L1609P	1609	Missense	proximal	1	no	10.370	11.924	EPSD	ICGC	9.540	Up-regulation
Atypical_PIKK_ATM_ATM_ST	Q5TZA2	CROCC	Q13315	ATM	S2009	A2006V	2006	Missense	distal	-3	no	9.589	10.453	EPSD	ICGC;COSMIC;GDSC	9.540	Up-regulation
Atypical_PIKK_ATM_ATM_ST	Q5TZA2	CROCC	Q13315	ATM	S2009	S2009F	2009	Missense	central	0	yes	9.589	0.000	EPSD	ICGC;COSMIC	9.540	Loss
Atypical_PIKK_ATM_ATM_ST	Q5TZA2	CROCC	Q13315	ATM	S2009	R2002Q	2002	Missense	distal	-7	no	9.589	9.789	EPSD	ICGC;CCLE	9.540	Up-regulation
Atypical_PIKK_ATM_ATM_ST	Q5TZA2	CROCC	Q13315	ATM	S2009	F2008L	2008	Missense	proximal	-1	no	9.589	9.881	EPSD	ICGC;COSMIC	9.540	Up-regulation
Atypical_PIKK_ATM_ATM_ST	Q5TZA2	CROCC	Q13315	ATM	S2009	S2009Y	2009	Missense	central	0	yes	9.589	0.000	EPSD	ICGC;COSMIC	9.540	Loss
Atypical_PIKK_ATM_ATM_ST	Q96J02	ITCH	Q13315	ATM	S6	M11I	11	Missense	distal	5	no	12.929	12.954	EPSD	ICGC;COSMIC	9.540	Up-regulation
Atypical_PIKK_ATM_ATM_ST	Q96J02	ITCH	Q13315	ATM	S18	M16V	16	Missense	proximal	-2	no	14.695	14.469	EPSD	ICGC;COSMIC	9.540	Down-regulation
Atypical_PIKK_ATM_ATM_ST	Q96J02	ITCH	Q13315	ATM	S18	M11I	11	Missense	distal	-7	no	14.695	14.506	EPSD	ICGC;COSMIC	9.540	Down-regulation
Atypical_PIKK_ATM_ATM_ST	Q96J02	ITCH	Q13315	ATM	S62	C57Y	57	Missense	distal	-5	no	11.024	10.955	EPSD	ICGC;COSMIC	9.540	Down-regulation
Atypical_PIKK_ATM_ATM_ST	Q96J02	ITCH	Q13315	ATM	S62	L69I	69	Missense	distal	7	no	11.024	11.036	EPSD	ICGC;COSMIC	9.540	Up-regulation
Atypical_PIKK_ATM_ATM_ST	Q96J02	ITCH	Q13315	ATM	S62	W65L	65	Missense	distal	3	no	11.024	10.928	EPSD	ICGC;COSMIC	9.540	Down-regulation
Atypical_PIKK_ATM_ATM_ST	Q96J02	ITCH	Q13315	ATM	S221	D226N	226	Missense	distal	5	no	11.165	11.053	EPSD	ICGC;COSMIC	9.540	Down-regulation
Atypical_PIKK_ATM_ATM_ST	Q96J02	ITCH	Q13315	ATM	S221	T218A	218	Missense	distal	-3	no	11.165	10.787	EPSD	ICGC;COSMIC	9.540	Down-regulation
Atypical_PIKK_ATM_ATM_ST	Q96J02	ITCH	Q13315	ATM	S221	S221L	221	Missense	central	0	yes	11.165	0.000	EPSD	ICGC;COSMIC	9.540	Loss
Atypical_PIKK_ATM_ATM_ST	Q96J02	ITCH	Q13315	ATM	S221	A227S	227	Missense	distal	6	no	11.165	11.158	EPSD	ICGC	9.540	Down-regulation
Atypical_PIKK_ATM_ATM_ST	Q96J02	ITCH	Q13315	ATM	S240	G247S	247	Missense	distal	7	no	9.932	9.890	EPSD	ICGC;COSMIC	9.540	Down-regulation
Atypical_PIKK_ATM_ATM_ST	Q96J02	ITCH	Q13315	ATM	S687	I689M	689	Missense	proximal	2	no	10.240	9.867	EPSD	ICGC;COSMIC	9.540	Down-regulation
Atypical_PIKK_ATM_ATM_ST	Q9BXW9	FANCD2	Q13315	ATM	S134	L139F	139	Missense	distal	5	no	9.680	9.822	EPSD	ICGC	9.540	Up-regulation
Atypical_PIKK_ATM_ATM_ST	Q9BXW9	FANCD2	Q13315	ATM	S134	M127L	127	Missense	distal	-7	no	9.680	9.568	EPSD	ICGC	9.540	Down-regulation
Atypical_PIKK_ATM_ATM_ST	Q9BXW9	FANCD2	Q13315	ATM	S178	I176V	176	Missense	proximal	-2	no	10.508	10.533	EPSD	ICGC;COSMIC	9.540	Up-regulation
Atypical_PIKK_ATM_ATM_ST	Q9BXW9	FANCD2	Q13315	ATM	S178	Q179K	179	Missense	proximal	1	no	10.508	3.660	EPSD	ICGC;COSMIC	9.540	Loss
Atypical_PIKK_ATM_ATM_ST	Q9BXW9	FANCD2	Q13315	ATM	S222	D221Y	221	Missense	proximal	-1	no	13.575	13.581	PhosphoSitePlus;EPSD	ICGC;COSMIC	9.540	Up-regulation
Atypical_PIKK_ATM_ATM_ST	Q9BXW9	FANCD2	Q13315	ATM	S222	Q223K	223	Missense	proximal	1	no	13.575	6.727	PhosphoSitePlus;EPSD	ICGC;COSMIC	9.540	Loss
Atypical_PIKK_ATM_ATM_ST	Q9BXW9	FANCD2	Q13315	ATM	S319	A318G	318	Missense	proximal	-1	no	12.400	12.369	EPSD	ICGC;COSMIC	9.540	Down-regulation
Atypical_PIKK_ATM_ATM_ST	Q9BXW9	FANCD2	Q13315	ATM	S319	R315L	315	Missense	distal	-4	no	12.400	12.271	EPSD	ICGC;COSMIC	9.540	Down-regulation
Atypical_PIKK_ATM_ATM_ST	Q9BXW9	FANCD2	Q13315	ATM	S592	S590R	590	Missense	proximal	-2	no	10.502	10.059	EPSD	ICGC;COSMIC	9.540	Down-regulation
Atypical_PIKK_ATM_ATM_ST	Q9BXW9	FANCD2	Q13315	ATM	T596	S590R	590	Missense	distal	-6	no	13.484	13.303	EPSD	ICGC;COSMIC	9.540	Down-regulation
Atypical_PIKK_ATM_ATM_ST	Q9BXW9	FANCD2	Q13315	ATM	T691	G685R	685	Missense	distal	-6	no	14.390	14.411	EPSD;PhosphoSitePlus	ICGC;COSMIC	9.540	Up-regulation
Atypical_PIKK_ATM_ATM_ST	Q9BXW9	FANCD2	Q13315	ATM	S717	Q718E	718	Missense	proximal	1	no	14.837	8.941	EPSD;PhosphoSitePlus	ICGC	9.540	Loss
Atypical_PIKK_ATM_ATM_ST	Q9BXW9	FANCD2	Q13315	ATM	S717	G721V	721	Missense	distal	4	no	14.837	15.014	EPSD;PhosphoSitePlus	ICGC	9.540	Up-regulation
Atypical_PIKK_ATM_ATM_ST	Q9BXW9	FANCD2	Q13315	ATM	S717	D711E	711	Missense	distal	-6	no	14.837	15.052	EPSD;PhosphoSitePlus	ICGC;COSMIC	9.540	Up-regulation
Atypical_PIKK_ATM_ATM_ST	Q9BXW9	FANCD2	Q13315	ATM	S717	S720L	720	Missense	distal	3	no	14.837	15.119	EPSD;PhosphoSitePlus	ICGC	9.540	Up-regulation
Atypical_PIKK_ATM_ATM_ST	Q9BXW9	FANCD2	Q13315	ATM	S784	C783R	783	Missense	proximal	-1	no	10.251	10.076	EPSD	ICGC;COSMIC	9.540	Down-regulation
Atypical_PIKK_ATM_ATM_ST	Q9BXW9	FANCD2	Q13315	ATM	S784	R779C	779	Missense	distal	-5	no	10.251	10.268	EPSD	ICGC;COSMIC	9.540	Up-regulation
Atypical_PIKK_ATM_ATM_ST	Q9BXW9	FANCD2	Q13315	ATM	T896	T896M	896	Missense	central	0	yes	9.883	0.000	EPSD	ICGC;COSMIC	9.540	Loss
Atypical_PIKK_ATM_ATM_ST	Q9BXW9	FANCD2	Q13315	ATM	T981	A985S	985	Missense	distal	4	no	9.631	9.979	EPSD	ICGC	9.540	Up-regulation
Atypical_PIKK_ATM_ATM_ST	Q9BXW9	FANCD2	Q13315	ATM	T981	L980V	980	Missense	proximal	-1	no	9.631	9.343	EPSD	ICGC;COSMIC	9.540	Loss
Atypical_PIKK_ATM_ATM_ST	Q9BXW9	FANCD2	Q13315	ATM	T981	P982L	982	Missense	proximal	1	no	9.631	8.077	EPSD	ICGC	9.540	Loss
Atypical_PIKK_ATM_ATM_ST	Q9BXW9	FANCD2	Q13315	ATM	S1257	S1257A	1257	Missense	central	0	yes	16.719	0.000	EPSD	ICGC	9.540	Loss
Atypical_PIKK_ATM_ATM_ST	Q9BXW9	FANCD2	Q13315	ATM	S1401	Q1402H	1402	Missense	proximal	1	no	13.353	-1.556	EPSD	ICGC	9.540	Loss
Atypical_PIKK_ATM_ATM_ST	Q9BXW9	FANCD2	Q13315	ATM	S1401	I1399N	1399	Missense	proximal	-2	no	13.353	13.863	EPSD	ICGC;COSMIC	9.540	Up-regulation
Atypical_PIKK_ATM_ATM_ST	Q9BXW9	FANCD2	Q13315	ATM	S1401	L1394F	1394	Missense	distal	-7	no	13.353	13.111	EPSD	ICGC	9.540	Down-regulation
Atypical_PIKK_ATM_ATM_ST	Q9BXW9	FANCD2	Q13315	ATM	S1401	K1400N	1400	Missense	proximal	-1	no	13.353	13.490	EPSD	ICGC	9.540	Up-regulation
Atypical_PIKK_ATM_ATM_ST	Q9BXW9	FANCD2	Q13315	ATM	S1404	Q1402H	1402	Missense	proximal	-2	no	16.008	15.705	EPSD	ICGC	9.540	Down-regulation
Atypical_PIKK_ATM_ATM_ST	Q9BXW9	FANCD2	Q13315	ATM	S1404	I1399N	1399	Missense	distal	-5	no	16.008	15.866	EPSD	ICGC;COSMIC	9.540	Down-regulation
Atypical_PIKK_ATM_ATM_ST	Q9BXW9	FANCD2	Q13315	ATM	S1404	K1400N	1400	Missense	distal	-4	no	16.008	15.773	EPSD	ICGC	9.540	Down-regulation
Atypical_PIKK_ATM_ATM_ST	Q9BXW9	FANCD2	Q13315	ATM	S1404	E1411G	1411	Missense	distal	7	no	16.008	16.053	EPSD	ICGC	9.540	Up-regulation
Atypical_PIKK_ATM_ATM_ST	Q9BXW9	FANCD2	Q13315	ATM	S1404	E1411D	1411	Missense	distal	7	no	16.008	16.021	EPSD	ICGC;COSMIC	9.540	Up-regulation
Atypical_PIKK_ATM_ATM_ST	Q9BXW9	FANCD2	Q13315	ATM	S1412	E1411G	1411	Missense	proximal	-1	no	10.826	10.424	EPSD	ICGC	9.540	Down-regulation
Atypical_PIKK_ATM_ATM_ST	Q9BXW9	FANCD2	Q13315	ATM	S1412	E1411D	1411	Missense	proximal	-1	no	10.826	10.562	EPSD	ICGC;COSMIC	9.540	Down-regulation
Atypical_PIKK_ATM_ATM_ST	Q9BXW9	FANCD2	Q13315	ATM	S1418	E1411G	1411	Missense	distal	-7	no	15.697	14.828	EPSD	ICGC	9.540	Down-regulation
Atypical_PIKK_ATM_ATM_ST	Q9BXW9	FANCD2	Q13315	ATM	S1418	K1422N	1422	Missense	distal	4	no	15.697	15.744	EPSD	ICGC	9.540	Up-regulation
Atypical_PIKK_ATM_ATM_ST	Q9BXW9	FANCD2	Q13315	ATM	S1418	E1411D	1411	Missense	distal	-7	no	15.697	15.119	EPSD	ICGC;COSMIC	9.540	Down-regulation
Atypical_PIKK_ATM_ATM_ST	Q9BXW9	FANCD2	Q13315	ATM	S1443	G1437E	1437	Missense	distal	-6	no	10.763	11.152	EPSD	ICGC	9.540	Up-regulation
Atypical_PIKK_ATM_ATM_ST	Q9BXW9	FANCD2	Q13315	ATM	S1443	E1445A	1445	Missense	proximal	2	no	10.763	9.669	EPSD	ICGC;COSMIC	9.540	Down-regulation
Atypical_PIKK_ATM_ATM_ST	Q9BXW9	FANCD2	Q13315	ATM	S1446	E1445A	1445	Missense	proximal	-1	no	12.229	11.858	EPSD	ICGC;COSMIC	9.540	Down-regulation
Atypical_PIKK_ATM_ATM_ST	Q9BXW9	FANCD2	Q13315	ATM	S1450	E1445A	1445	Missense	distal	-5	no	9.570	9.728	EPSD	ICGC;COSMIC	9.540	Up-regulation
Atypical_PIKK_ATM_ATM_ST	Q969H0	FBXW7	Q13315	ATM	S26	R20I	20	Missense	distal	-6	no	15.064	14.843	PhosphoSitePlus	ICGC;COSMIC	9.540	Down-regulation
Atypical_PIKK_ATM_ATM_ST	Q969H0	FBXW7	Q13315	ATM	S26	P23S	23	Missense	distal	-3	no	15.064	14.867	PhosphoSitePlus	ICGC;COSMIC	9.540	Down-regulation
Atypical_PIKK_ATM_ATM_ST	Q969H0	FBXW7	Q13315	ATM	T205	P201T	201	Missense	distal	-4	no	9.311	9.597	EPSD	ICGC	9.540	Gain
Atypical_PIKK_ATM_ATM_ST	Q6PCD5	RFWD3	Q13315	ATM	S428	H432N	432	Missense	distal	4	no	10.097	10.107	EPSD	ICGC	9.540	Up-regulation
Atypical_PIKK_ATM_ATM_ST	Q6PCD5	RFWD3	Q13315	ATM	S428	Q429K	429	Missense	proximal	1	no	10.097	3.249	EPSD	ICGC	9.540	Loss
Atypical_PIKK_ATM_ATM_ST	Q6PCD5	RFWD3	Q13315	ATM	S490	Q491K	491	Missense	proximal	1	no	15.096	8.247	EPSD	ICGC	9.540	Loss
Atypical_PIKK_ATM_ATM_ST	Q6PCD5	RFWD3	Q13315	ATM	S490	S490I	490	Missense	central	0	yes	15.096	0.000	EPSD	ICGC;COSMIC	9.540	Loss
Atypical_PIKK_ATM_ATM_ST	Q9UQR1	ZNF148	Q13315	ATM	S23	E19K	19	Missense	distal	-4	no	10.657	9.685	EPSD	ICGC;COSMIC	9.540	Down-regulation
Atypical_PIKK_ATM_ATM_ST	Q9UQR1	ZNF148	Q13315	ATM	S202	I209T	209	Missense	distal	7	no	12.906	12.891	PhosphoSitePlus	ICGC;COSMIC	9.540	Down-regulation
Atypical_PIKK_ATM_ATM_ST	Q9UQR1	ZNF148	Q13315	ATM	S202	C204Y	204	Missense	proximal	2	no	12.906	13.299	PhosphoSitePlus	ICGC;COSMIC	9.540	Up-regulation
Atypical_PIKK_ATM_ATM_ST	Q9UQR1	ZNF148	Q13315	ATM	S202	Q203K	203	Missense	proximal	1	no	12.906	6.057	PhosphoSitePlus	ICGC	9.540	Loss
Atypical_PIKK_ATM_ATM_ST	Q9UQR1	ZNF148	Q13315	ATM	S250	T248A	248	Missense	proximal	-2	no	9.873	9.773	EPSD	ICGC	9.540	Down-regulation
Atypical_PIKK_ATM_ATM_ST	Q9UQR1	ZNF148	Q13315	ATM	S297	E298Q	298	Missense	proximal	1	no	10.670	16.567	EPSD	ICGC	9.540	Up-regulation
Atypical_PIKK_ATM_ATM_ST	Q9UQR1	ZNF148	Q13315	ATM	S297	D300Y	300	Missense	distal	3	no	10.670	10.728	EPSD	ICGC	9.540	Up-regulation
Atypical_PIKK_ATM_ATM_ST	Q9UQR1	ZNF148	Q13315	ATM	S306	N310K	310	Missense	distal	4	no	9.859	9.811	EPSD	ICGC;COSMIC	9.540	Down-regulation
Atypical_PIKK_ATM_ATM_ST	Q9UQR1	ZNF148	Q13315	ATM	S306	D300Y	300	Missense	distal	-6	no	9.859	9.636	EPSD	ICGC	9.540	Down-regulation
Atypical_PIKK_ATM_ATM_ST	Q9UQR1	ZNF148	Q13315	ATM	S625	A621V	621	Missense	distal	-4	no	9.773	9.294	EPSD	ICGC	9.540	Loss
Atypical_PIKK_ATM_ATM_ST	Q9UQR1	ZNF148	Q13315	ATM	S625	P626L	626	Missense	proximal	1	no	9.773	8.219	EPSD	ICGC	9.540	Loss
Atypical_PIKK_ATM_ATM_ST	Q9UQR1	ZNF148	Q13315	ATM	T702	N695K	695	Missense	distal	-7	no	14.876	14.750	EPSD	ICGC	9.540	Down-regulation
Atypical_PIKK_ATM_ATM_ST	Q9UQR1	ZNF148	Q13315	ATM	S763	A764D	764	Missense	proximal	1	no	9.279	10.121	EPSD	ICGC	9.540	Gain
Atypical_PIKK_ATM_ATM_ST	Q9UQR1	ZNF148	Q13315	ATM	S784	A779T	779	Missense	distal	-5	no	13.254	13.173	EPSD	ICGC	9.540	Down-regulation
Atypical_PIKK_ATM_ATM_ST	Q9UQR1	ZNF148	Q13315	ATM	S784	R778G	778	Missense	distal	-6	no	13.254	13.233	EPSD	ICGC;COSMIC	9.540	Down-regulation
Atypical_PIKK_ATM_ATM_ST	Q96RL1	UIMC1	Q13315	ATM	S26	S27Y	27	Missense	proximal	1	no	4.038	10.099	EPSD	ICGC;COSMIC	9.540	Gain
Atypical_PIKK_ATM_ATM_ST	Q96RL1	UIMC1	Q13315	ATM	S140	P133S	133	Missense	distal	-7	no	16.313	16.549	EPSD	ICGC	9.540	Up-regulation
Atypical_PIKK_ATM_ATM_ST	Q96RL1	UIMC1	Q13315	ATM	S171	H169N	169	Missense	proximal	-2	no	10.004	10.251	EPSD	ICGC	9.540	Up-regulation
Atypical_PIKK_ATM_ATM_ST	Q96RL1	UIMC1	Q13315	ATM	S419	A418D	418	Missense	proximal	-1	no	16.206	16.312	EPSD	ICGC	9.540	Up-regulation
Atypical_PIKK_ATM_ATM_ST	Q96RL1	UIMC1	Q13315	ATM	T448	Q449K	449	Missense	proximal	1	no	11.381	4.533	EPSD	ICGC	9.540	Loss
Atypical_PIKK_ATM_ATM_ST	Q96RL1	UIMC1	Q13315	ATM	T448	S452F	452	Missense	distal	4	no	11.381	12.209	EPSD	ICGC;GDSC;CCLE	9.540	Up-regulation
Atypical_PIKK_ATM_ATM_ST	Q96RL1	UIMC1	Q13315	ATM	T448	T448N	448	Missense	central	0	yes	11.381	0.000	EPSD	ICGC	9.540	Loss
Atypical_PIKK_ATM_ATM_ST	Q96RL1	UIMC1	Q13315	ATM	S453	Q449K	449	Missense	distal	-4	no	10.311	10.062	EPSD	ICGC	9.540	Down-regulation
Atypical_PIKK_ATM_ATM_ST	Q96RL1	UIMC1	Q13315	ATM	S453	S452F	452	Missense	proximal	-1	no	10.311	9.884	EPSD	ICGC;GDSC;CCLE	9.540	Down-regulation
Atypical_PIKK_ATM_ATM_ST	Q96RL1	UIMC1	Q13315	ATM	S453	T448N	448	Missense	distal	-5	no	10.311	10.372	EPSD	ICGC	9.540	Up-regulation
Atypical_PIKK_ATM_ATM_ST	Q96RL1	UIMC1	Q13315	ATM	S463	E461D	461	Missense	proximal	-2	no	10.005	9.526	EPSD	ICGC;COSMIC	9.540	Loss
Atypical_PIKK_ATM_ATM_ST	Q96RL1	UIMC1	Q13315	ATM	S463	S463A	463	Missense	central	0	yes	10.005	0.000	EPSD	ICGC	9.540	Loss
Atypical_PIKK_ATM_ATM_ST	Q96T60	PNKP	Q13315	ATM	S114	P112R	112	Missense	proximal	-2	no	15.948	15.741	EPSD;PhosphoSitePlus	ICGC	9.540	Down-regulation
Atypical_PIKK_ATM_ATM_ST	Q96T60	PNKP	Q13315	ATM	S114	P119S	119	Missense	distal	5	no	15.948	15.766	EPSD;PhosphoSitePlus	ICGC;COSMIC;CCLE	9.540	Down-regulation
Atypical_PIKK_ATM_ATM_ST	Q96T60	PNKP	Q13315	ATM	S114	D117Y	117	Missense	distal	3	no	15.948	16.006	EPSD;PhosphoSitePlus	ICGC;COSMIC	9.540	Up-regulation
Atypical_PIKK_ATM_ATM_ST	Q96T60	PNKP	Q13315	ATM	S126	A133D	133	Missense	distal	7	no	14.074	14.052	PhosphoSitePlus;EPSD	ICGC	9.540	Down-regulation
Atypical_PIKK_ATM_ATM_ST	Q96T60	PNKP	Q13315	ATM	S126	P119S	119	Missense	distal	-7	no	14.074	14.310	PhosphoSitePlus;EPSD	ICGC;COSMIC;CCLE	9.540	Up-regulation
Atypical_PIKK_ATM_ATM_ST	Q01094	E2F1	Q13315	ATM	S131	R138H	138	Missense	distal	7	no	9.642	9.636	EPSD	ICGC;COSMIC	9.540	Down-regulation
Atypical_PIKK_ATM_ATM_ST	Q01094	E2F1	Q13315	ATM	S307	P308T	308	Missense	proximal	1	no	9.855	4.848	EPSD	ICGC	9.540	Loss
Atypical_PIKK_ATM_ATM_ST	Q01094	E2F1	Q13315	ATM	S307	G305W	305	Missense	proximal	-2	no	9.855	9.804	EPSD	ICGC;COSMIC	9.540	Down-regulation
Atypical_PIKK_ATM_ATM_ST	Q01094	E2F1	Q13315	ATM	S307	G305V	305	Missense	proximal	-2	no	9.855	9.633	EPSD	ICGC;COSMIC	9.540	Down-regulation
Atypical_PIKK_ATM_ATM_ST	Q01094	E2F1	Q13315	ATM	S313	P308T	308	Missense	distal	-5	no	13.870	13.777	EPSD	ICGC	9.540	Down-regulation
Atypical_PIKK_ATM_ATM_ST	Q01094	E2F1	Q13315	ATM	S313	S318A	318	Missense	distal	5	no	13.870	13.917	EPSD	ICGC	9.540	Up-regulation
Atypical_PIKK_ATM_ATM_ST	Q01094	E2F1	Q13315	ATM	S318	S318A	318	Missense	central	0	yes	9.741	0.000	EPSD	ICGC	9.540	Loss
Atypical_PIKK_ATM_ATM_ST	Q01094	E2F1	Q13315	ATM	S375	V369M	369	Missense	distal	-6	no	9.644	9.656	EPSD	ICGC	9.540	Up-regulation
Atypical_PIKK_ATM_ATM_ST	Q00987	MDM2	Q13315	ATM	S17	G12R	12	Missense	distal	-5	no	15.241	15.262	EPSD	ICGC;COSMIC	9.540	Up-regulation
Atypical_PIKK_ATM_ATM_ST	Q00987	MDM2	Q13315	ATM	S17	D11Y	11	Missense	distal	-6	no	15.241	15.018	EPSD	ICGC	9.540	Down-regulation
Atypical_PIKK_ATM_ATM_ST	Q00987	MDM2	Q13315	ATM	S17	T10A	10	Missense	distal	-7	no	15.241	15.225	EPSD	ICGC;COSMIC	9.540	Down-regulation
Atypical_PIKK_ATM_ATM_ST	Q00987	MDM2	Q13315	ATM	S186	S190C	190	Missense	distal	4	no	11.244	11.753	EPSD	ICGC;COSMIC	9.540	Up-regulation
Atypical_PIKK_ATM_ATM_ST	Q00987	MDM2	Q13315	ATM	S190	S190C	190	Missense	central	0	yes	11.378	0.000	EPSD	ICGC;COSMIC	9.540	Loss
Atypical_PIKK_ATM_ATM_ST	Q00987	MDM2	Q13315	ATM	S196	L199F	199	Missense	distal	3	no	10.268	10.567	EPSD	ICGC	9.540	Up-regulation
Atypical_PIKK_ATM_ATM_ST	Q00987	MDM2	Q13315	ATM	S196	S190C	190	Missense	distal	-6	no	10.268	9.888	EPSD	ICGC;COSMIC	9.540	Down-regulation
Atypical_PIKK_ATM_ATM_ST	Q00987	MDM2	Q13315	ATM	S260	E267K	267	Missense	distal	7	no	10.571	10.598	EPSD	ICGC;COSMIC	9.540	Up-regulation
Atypical_PIKK_ATM_ATM_ST	Q00987	MDM2	Q13315	ATM	S262	E267K	267	Missense	distal	5	no	11.792	11.966	EPSD	ICGC;COSMIC	9.540	Up-regulation
Atypical_PIKK_ATM_ATM_ST	Q00987	MDM2	Q13315	ATM	S269	E267K	267	Missense	proximal	-2	no	10.657	10.081	EPSD	ICGC;COSMIC	9.540	Down-regulation
Atypical_PIKK_ATM_ATM_ST	Q00987	MDM2	Q13315	ATM	S286	E285D	285	Missense	proximal	-1	no	9.990	9.726	EPSD	ICGC;COSMIC	9.540	Down-regulation
Atypical_PIKK_ATM_ATM_ST	Q00987	MDM2	Q13315	ATM	S386	E390Q	390	Missense	distal	4	no	14.863	15.194	EPSD;PhosphoSitePlus	ICGC;COSMIC	9.540	Up-regulation
Atypical_PIKK_ATM_ATM_ST	Q00987	MDM2	Q13315	ATM	S388	E390Q	390	Missense	proximal	2	no	15.194	14.381	EPSD	ICGC;COSMIC	9.540	Down-regulation
Atypical_PIKK_ATM_ATM_ST	Q00987	MDM2	Q13315	ATM	S395	S400C	400	Missense	distal	5	no	14.526	14.752	EPSD;PhosphoSitePlus	ICGC;COSMIC	9.540	Up-regulation
Atypical_PIKK_ATM_ATM_ST	Q00987	MDM2	Q13315	ATM	S395	E390Q	390	Missense	distal	-5	no	14.526	14.558	EPSD;PhosphoSitePlus	ICGC;COSMIC	9.540	Up-regulation
Atypical_PIKK_ATM_ATM_ST	Q00987	MDM2	Q13315	ATM	S407	S400C	400	Missense	distal	-7	no	16.962	16.289	PhosphoSitePlus;EPSD	ICGC;COSMIC	9.540	Down-regulation
Atypical_PIKK_ATM_ATM_ST	Q00987	MDM2	Q13315	ATM	T419	V426F	426	Missense	distal	7	no	17.081	17.093	EPSD;PhosphoSitePlus	ICGC	9.540	Up-regulation
Atypical_PIKK_ATM_ATM_ST	Q00987	MDM2	Q13315	ATM	S429	V426F	426	Missense	distal	-3	no	12.182	12.836	EPSD;PhosphoSitePlus	ICGC	9.540	Up-regulation
Atypical_PIKK_ATM_ATM_ST	O96017	CHEK2	Q13315	ATM	S33	G37C	37	Missense	distal	4	no	16.155	16.536	PhosphoSitePlus;EPSD	ICGC;COSMIC	9.540	Up-regulation
Atypical_PIKK_ATM_ATM_ST	O96017	CHEK2	Q13315	ATM	S35	G37C	37	Missense	proximal	2	no	13.848	13.452	EPSD;PhosphoSitePlus	ICGC;COSMIC	9.540	Down-regulation
Atypical_PIKK_ATM_ATM_ST	O96017	CHEK2	Q13315	ATM	S50	M46I	46	Missense	distal	-4	no	15.257	15.553	EPSD	ICGC;COSMIC	9.540	Up-regulation
Atypical_PIKK_ATM_ATM_ST	O96017	CHEK2	Q13315	ATM	S50	S49F	49	Missense	proximal	-1	no	15.257	14.830	EPSD	ICGC;COSMIC	9.540	Down-regulation
Atypical_PIKK_ATM_ATM_ST	O96017	CHEK2	Q13315	ATM	S50	T45M	45	Missense	distal	-5	no	15.257	15.430	EPSD	ICGC;COSMIC	9.540	Up-regulation
Atypical_PIKK_ATM_ATM_ST	O96017	CHEK2	Q13315	ATM	S140	R145W	145	Missense	distal	5	no	10.517	10.541	EPSD	ICGC;COSMIC;CCLE	9.540	Up-regulation
Atypical_PIKK_ATM_ATM_ST	O96017	CHEK2	Q13315	ATM	S140	R145Q	145	Missense	distal	5	no	10.517	10.405	EPSD	ICGC;COSMIC	9.540	Down-regulation
Atypical_PIKK_ATM_ATM_ST	O96017	CHEK2	Q13315	ATM	S140	H143N	143	Missense	distal	3	no	10.517	10.494	EPSD	ICGC;COSMIC	9.540	Down-regulation
Atypical_PIKK_ATM_ATM_ST	O96017	CHEK2	Q13315	ATM	S140	T138A	138	Missense	proximal	-2	no	10.517	10.417	EPSD	ICGC;COSMIC	9.540	Down-regulation
Atypical_PIKK_ATM_ATM_ST	O96017	CHEK2	Q13315	ATM	S140	H143Q	143	Missense	distal	3	no	10.517	10.377	EPSD	ICGC;COSMIC	9.540	Down-regulation
Atypical_PIKK_ATM_ATM_ST	O96017	CHEK2	Q13315	ATM	S140	D134Y	134	Missense	distal	-6	no	10.517	10.294	EPSD	ICGC;COSMIC	9.540	Down-regulation
Atypical_PIKK_ATM_ATM_ST	O96017	CHEK2	Q13315	ATM	S140	K135T	135	Missense	distal	-5	no	10.517	10.511	EPSD	ICGC;COSMIC	9.540	Down-regulation
Atypical_PIKK_ATM_ATM_ST	O96017	CHEK2	Q13315	ATM	S192	K197Q	197	Missense	distal	5	no	10.945	10.995	EPSD	ICGC;COSMIC	9.540	Up-regulation
Atypical_PIKK_ATM_ATM_ST	O96017	CHEK2	Q13315	ATM	S192	R195K	195	Missense	distal	3	no	10.945	10.873	EPSD	ICGC;COSMIC	9.540	Down-regulation
Atypical_PIKK_ATM_ATM_ST	O96017	CHEK2	Q13315	ATM	S192	N186S	186	Missense	distal	-6	no	10.945	11.061	EPSD	ICGC;COSMIC	9.540	Up-regulation
Atypical_PIKK_ATM_ATM_ST	O96017	CHEK2	Q13315	ATM	S357	E359K	359	Missense	proximal	2	no	14.674	13.343	EPSD	ICGC;COSMIC	9.540	Down-regulation
Atypical_PIKK_ATM_ATM_ST	O96017	CHEK2	Q13315	ATM	S357	L363F	363	Missense	distal	6	no	14.674	14.654	EPSD	ICGC;COSMIC	9.540	Down-regulation
Atypical_PIKK_ATM_ATM_ST	O96017	CHEK2	Q13315	ATM	S357	L355R	355	Missense	proximal	-2	no	14.674	14.621	EPSD	ICGC	9.540	Down-regulation
Atypical_PIKK_ATM_ATM_ST	O96017	CHEK2	Q13315	ATM	S357	E351D	351	Missense	distal	-6	no	14.674	14.460	EPSD	ICGC;COSMIC	9.540	Down-regulation
Atypical_PIKK_ATM_ATM_ST	O96017	CHEK2	Q13315	ATM	S357	L354V	354	Missense	distal	-3	no	14.674	14.884	EPSD	ICGC;COSMIC	9.540	Up-regulation
Atypical_PIKK_ATM_ATM_ST	O96017	CHEK2	Q13315	ATM	T432	Q433E	433	Missense	proximal	1	no	10.889	4.993	EPSD	ICGC;COSMIC	9.540	Loss
Atypical_PIKK_ATM_ATM_ST	O96017	CHEK2	Q13315	ATM	T432	S428F	428	Missense	distal	-4	no	10.889	9.490	EPSD	ICGC;COSMIC	9.540	Loss
Atypical_PIKK_ATM_ATM_ST	O96017	CHEK2	Q13315	ATM	T432	H430Y	430	Missense	proximal	-2	no	10.889	11.147	EPSD	ICGC;COSMIC	9.540	Up-regulation
Atypical_PIKK_ATM_ATM_ST	O96017	CHEK2	Q13315	ATM	S500	A507V	507	Missense	distal	7	no	11.027	11.045	EPSD	ICGC	9.540	Up-regulation
Atypical_PIKK_ATM_ATM_ST	O96017	CHEK2	Q13315	ATM	S500	Q496P	496	Missense	distal	-4	no	11.027	10.803	EPSD	ICGC;COSMIC	9.540	Down-regulation
Atypical_PIKK_ATM_ATM_ST	O96017	CHEK2	Q13315	ATM	S500	F495I	495	Missense	distal	-5	no	11.027	10.818	EPSD	ICGC;COSMIC	9.540	Down-regulation
Atypical_PIKK_ATM_ATM_ST	Q8IY92	SLX4	Q13315	ATM	S115	K109R	109	Missense	distal	-6	no	13.628	13.561	EPSD	ICGC;COSMIC	9.540	Down-regulation
Atypical_PIKK_ATM_ATM_ST	Q8IY92	SLX4	Q13315	ATM	S173	E167K	167	Missense	distal	-6	no	9.696	9.395	EPSD	ICGC;COSMIC	9.540	Loss
Atypical_PIKK_ATM_ATM_ST	Q8IY92	SLX4	Q13315	ATM	S173	P168T	168	Missense	distal	-5	no	9.696	9.604	EPSD	ICGC	9.540	Down-regulation
Atypical_PIKK_ATM_ATM_ST	Q8IY92	SLX4	Q13315	ATM	S186	D185Y	185	Missense	proximal	-1	no	14.902	14.907	EPSD	ICGC;COSMIC	9.540	Up-regulation
Atypical_PIKK_ATM_ATM_ST	Q8IY92	SLX4	Q13315	ATM	S228	P221T	221	Missense	distal	-7	no	9.626	9.781	EPSD	ICGC	9.540	Up-regulation
Atypical_PIKK_ATM_ATM_ST	Q8IY92	SLX4	Q13315	ATM	S228	A235T	235	Missense	distal	7	no	9.626	9.611	EPSD	ICGC	9.540	Down-regulation
Atypical_PIKK_ATM_ATM_ST	Q8IY92	SLX4	Q13315	ATM	S264	A261V	261	Missense	distal	-3	no	8.996	9.859	EPSD	ICGC	9.540	Gain
Atypical_PIKK_ATM_ATM_ST	Q8IY92	SLX4	Q13315	ATM	S383	M386V	386	Missense	distal	3	no	12.279	12.366	EPSD	ICGC;COSMIC	9.540	Up-regulation
Atypical_PIKK_ATM_ATM_ST	Q8IY92	SLX4	Q13315	ATM	S467	S467P	467	Missense	central	0	yes	11.693	0.000	EPSD	ICGC;COSMIC	9.540	Loss
Atypical_PIKK_ATM_ATM_ST	Q8IY92	SLX4	Q13315	ATM	S492	S498C	498	Missense	distal	6	no	10.635	10.563	EPSD	ICGC;COSMIC;CCLE	9.540	Down-regulation
Atypical_PIKK_ATM_ATM_ST	Q8IY92	SLX4	Q13315	ATM	T500	S498C	498	Missense	proximal	-2	no	11.655	11.193	EPSD	ICGC;COSMIC;CCLE	9.540	Down-regulation
Atypical_PIKK_ATM_ATM_ST	Q8IY92	SLX4	Q13315	ATM	T500	P504S	504	Missense	distal	4	no	11.655	11.532	EPSD	ICGC	9.540	Down-regulation
Atypical_PIKK_ATM_ATM_ST	Q8IY92	SLX4	Q13315	ATM	S584	P585H	585	Missense	proximal	1	no	9.829	-0.278	EPSD	ICGC;COSMIC	9.540	Loss
Atypical_PIKK_ATM_ATM_ST	Q8IY92	SLX4	Q13315	ATM	S584	H588Q	588	Missense	distal	4	no	9.829	9.745	EPSD	ICGC	9.540	Down-regulation
Atypical_PIKK_ATM_ATM_ST	Q8IY92	SLX4	Q13315	ATM	S584	H588R	588	Missense	distal	4	no	9.829	9.893	EPSD	ICGC;COSMIC	9.540	Up-regulation
Atypical_PIKK_ATM_ATM_ST	Q8IY92	SLX4	Q13315	ATM	S584	R583S	583	Missense	proximal	-1	no	9.829	10.203	EPSD	ICGC;COSMIC	9.540	Up-regulation
Atypical_PIKK_ATM_ATM_ST	Q8IY92	SLX4	Q13315	ATM	S601	S603L	603	Missense	proximal	2	no	11.383	10.139	EPSD	ICGC;COSMIC	9.540	Down-regulation
Atypical_PIKK_ATM_ATM_ST	Q8IY92	SLX4	Q13315	ATM	S601	S601L	601	Missense	central	0	yes	11.383	0.000	EPSD	ICGC;COSMIC	9.540	Loss
Atypical_PIKK_ATM_ATM_ST	Q8IY92	SLX4	Q13315	ATM	S601	Q606E	606	Missense	distal	5	no	11.383	11.159	EPSD	ICGC	9.540	Down-regulation
Atypical_PIKK_ATM_ATM_ST	Q8IY92	SLX4	Q13315	ATM	S601	S605R	605	Missense	distal	4	no	11.383	11.565	EPSD	ICGC	9.540	Up-regulation
Atypical_PIKK_ATM_ATM_ST	Q8IY92	SLX4	Q13315	ATM	S605	S603L	603	Missense	proximal	-2	no	13.778	13.388	EPSD	ICGC;COSMIC	9.540	Down-regulation
Atypical_PIKK_ATM_ATM_ST	Q8IY92	SLX4	Q13315	ATM	S605	S601L	601	Missense	distal	-4	no	13.778	12.839	EPSD	ICGC;COSMIC	9.540	Down-regulation
Atypical_PIKK_ATM_ATM_ST	Q8IY92	SLX4	Q13315	ATM	S605	Q606E	606	Missense	proximal	1	no	13.778	7.881	EPSD	ICGC	9.540	Loss
Atypical_PIKK_ATM_ATM_ST	Q8IY92	SLX4	Q13315	ATM	S605	S605R	605	Missense	central	0	yes	13.778	0.000	EPSD	ICGC	9.540	Loss
Atypical_PIKK_ATM_ATM_ST	Q8IY92	SLX4	Q13315	ATM	S659	P658T	658	Missense	proximal	-1	no	14.326	14.629	EPSD	ICGC	9.540	Up-regulation
Atypical_PIKK_ATM_ATM_ST	Q8IY92	SLX4	Q13315	ATM	S659	H663N	663	Missense	distal	4	no	14.326	14.336	EPSD	ICGC	9.540	Up-regulation
Atypical_PIKK_ATM_ATM_ST	Q8IY92	SLX4	Q13315	ATM	S960	S957R	957	Missense	distal	-3	no	10.071	10.811	EPSD	ICGC;COSMIC	9.540	Up-regulation
Atypical_PIKK_ATM_ATM_ST	Q8IY92	SLX4	Q13315	ATM	S1066	R1062H	1062	Missense	distal	-4	no	12.570	12.700	EPSD	ICGC;COSMIC	9.540	Up-regulation
Atypical_PIKK_ATM_ATM_ST	Q8IY92	SLX4	Q13315	ATM	S1066	R1060W	1060	Missense	distal	-6	no	12.570	12.402	EPSD	ICGC;COSMIC;GDSC	9.540	Down-regulation
Atypical_PIKK_ATM_ATM_ST	Q8IY92	SLX4	Q13315	ATM	S1121	M1116V	1116	Missense	distal	-5	no	9.742	9.771	EPSD	ICGC;COSMIC	9.540	Up-regulation
Atypical_PIKK_ATM_ATM_ST	Q8IY92	SLX4	Q13315	ATM	S1121	P1122L	1122	Missense	proximal	1	no	9.742	8.187	EPSD	ICGC;COSMIC	9.540	Loss
Atypical_PIKK_ATM_ATM_ST	Q8IY92	SLX4	Q13315	ATM	S1121	Q1128L	1128	Missense	distal	7	no	9.742	9.751	EPSD	ICGC;COSMIC	9.540	Up-regulation
Atypical_PIKK_ATM_ATM_ST	Q8IY92	SLX4	Q13315	ATM	T1127	P1122L	1122	Missense	distal	-5	no	13.533	13.552	EPSD	ICGC;COSMIC	9.540	Up-regulation
Atypical_PIKK_ATM_ATM_ST	Q8IY92	SLX4	Q13315	ATM	T1127	Q1128L	1128	Missense	proximal	1	no	13.533	7.177	EPSD	ICGC;COSMIC	9.540	Loss
Atypical_PIKK_ATM_ATM_ST	Q8IY92	SLX4	Q13315	ATM	S1136	S1142L	1142	Missense	distal	6	no	11.058	11.002	EPSD	ICGC;COSMIC	9.540	Down-regulation
Atypical_PIKK_ATM_ATM_ST	Q8IY92	SLX4	Q13315	ATM	S1138	S1142L	1142	Missense	distal	4	no	14.212	14.554	EPSD;PhosphoSitePlus	ICGC;COSMIC	9.540	Up-regulation
Atypical_PIKK_ATM_ATM_ST	Q8IY92	SLX4	Q13315	ATM	S1157	L1154V	1154	Missense	distal	-3	no	9.526	9.735	EPSD	ICGC	9.540	Gain
Atypical_PIKK_ATM_ATM_ST	Q8IY92	SLX4	Q13315	ATM	S1185	K1179T	1179	Missense	distal	-6	no	11.136	11.180	EPSD	ICGC;COSMIC	9.540	Up-regulation
Atypical_PIKK_ATM_ATM_ST	Q8IY92	SLX4	Q13315	ATM	S1204	E1211K	1211	Missense	distal	7	no	16.055	16.082	EPSD	ICGC;COSMIC	9.540	Up-regulation
Atypical_PIKK_ATM_ATM_ST	Q8IY92	SLX4	Q13315	ATM	S1204	R1209T	1209	Missense	distal	5	no	16.055	15.873	EPSD	ICGC;COSMIC	9.540	Down-regulation
Atypical_PIKK_ATM_ATM_ST	Q8IY92	SLX4	Q13315	ATM	S1204	S1210N	1210	Missense	distal	6	no	16.055	16.045	EPSD	ICGC;COSMIC	9.540	Down-regulation
Atypical_PIKK_ATM_ATM_ST	Q8IY92	SLX4	Q13315	ATM	S1204	S1204F	1204	Missense	central	0	yes	16.055	0.000	EPSD	ICGC	9.540	Loss
Atypical_PIKK_ATM_ATM_ST	Q8IY92	SLX4	Q13315	ATM	S1206	E1211K	1211	Missense	distal	5	no	10.248	10.423	EPSD	ICGC;COSMIC	9.540	Up-regulation
Atypical_PIKK_ATM_ATM_ST	Q8IY92	SLX4	Q13315	ATM	S1206	R1209T	1209	Missense	distal	3	no	10.248	10.143	EPSD	ICGC;COSMIC	9.540	Down-regulation
Atypical_PIKK_ATM_ATM_ST	Q8IY92	SLX4	Q13315	ATM	S1206	S1210N	1210	Missense	distal	4	no	10.248	10.375	EPSD	ICGC;COSMIC	9.540	Up-regulation
Atypical_PIKK_ATM_ATM_ST	Q8IY92	SLX4	Q13315	ATM	S1206	S1204F	1204	Missense	proximal	-2	no	10.248	9.348	EPSD	ICGC	9.540	Loss
Atypical_PIKK_ATM_ATM_ST	Q8IY92	SLX4	Q13315	ATM	S1244	A1248D	1248	Missense	distal	4	no	9.560	10.115	EPSD	ICGC;COSMIC	9.540	Up-regulation
Atypical_PIKK_ATM_ATM_ST	Q8IY92	SLX4	Q13315	ATM	S1246	A1248D	1248	Missense	proximal	2	no	8.739	9.702	EPSD	ICGC;COSMIC	9.540	Gain
Atypical_PIKK_ATM_ATM_ST	Q8IY92	SLX4	Q13315	ATM	T1260	P1261Q	1261	Missense	proximal	1	no	7.790	12.592	EPSD	ICGC;COSMIC	9.540	Gain
Atypical_PIKK_ATM_ATM_ST	Q8IY92	SLX4	Q13315	ATM	S1271	R1267H	1267	Missense	distal	-4	no	14.329	14.460	EPSD;PhosphoSitePlus	ICGC;COSMIC	9.540	Up-regulation
Atypical_PIKK_ATM_ATM_ST	Q8IY92	SLX4	Q13315	ATM	S1271	S1271F	1271	Missense	central	0	yes	14.329	0.000	EPSD;PhosphoSitePlus	ICGC;COSMIC	9.540	Loss
Atypical_PIKK_ATM_ATM_ST	Q8IY92	SLX4	Q13315	ATM	T1273	R1267H	1267	Missense	distal	-6	no	10.277	10.278	EPSD	ICGC;COSMIC	9.540	Up-regulation
Atypical_PIKK_ATM_ATM_ST	Q8IY92	SLX4	Q13315	ATM	T1273	S1271F	1271	Missense	proximal	-2	no	10.277	9.376	EPSD	ICGC;COSMIC	9.540	Loss
Atypical_PIKK_ATM_ATM_ST	Q8IY92	SLX4	Q13315	ATM	T1288	V1287M	1287	Missense	proximal	-1	no	12.351	12.483	EPSD	ICGC;COSMIC	9.540	Up-regulation
Atypical_PIKK_ATM_ATM_ST	Q8IY92	SLX4	Q13315	ATM	T1288	H1290N	1290	Missense	proximal	2	no	12.351	12.391	EPSD	ICGC;COSMIC	9.540	Up-regulation
Atypical_PIKK_ATM_ATM_ST	Q8IY92	SLX4	Q13315	ATM	S1355	G1349R	1349	Missense	distal	-6	no	9.791	9.812	EPSD	ICGC;COSMIC	9.540	Up-regulation
Atypical_PIKK_ATM_ATM_ST	Q8IY92	SLX4	Q13315	ATM	S1355	P1352Q	1352	Missense	distal	-3	no	9.791	9.560	EPSD	ICGC	9.540	Down-regulation
Atypical_PIKK_ATM_ATM_ST	Q8IY92	SLX4	Q13315	ATM	S1355	P1361H	1361	Missense	distal	6	no	9.791	9.769	EPSD	ICGC	9.540	Down-regulation
Atypical_PIKK_ATM_ATM_ST	Q8IY92	SLX4	Q13315	ATM	S1398	E1394K	1394	Missense	distal	-4	no	10.311	9.339	EPSD	ICGC	9.540	Loss
Atypical_PIKK_ATM_ATM_ST	Q8IY92	SLX4	Q13315	ATM	S1453	G1447C	1447	Missense	distal	-6	no	11.360	11.181	EPSD	ICGC;COSMIC	9.540	Down-regulation
Atypical_PIKK_ATM_ATM_ST	Q8IY92	SLX4	Q13315	ATM	S1453	R1456S	1456	Missense	distal	3	no	11.360	11.174	EPSD	ICGC	9.540	Down-regulation
Atypical_PIKK_ATM_ATM_ST	Q8IY92	SLX4	Q13315	ATM	S1455	R1456S	1456	Missense	proximal	1	no	9.774	4.649	EPSD	ICGC	9.540	Loss
Atypical_PIKK_ATM_ATM_ST	Q8IY92	SLX4	Q13315	ATM	S1469	P1470Q	1470	Missense	proximal	1	no	7.644	12.446	EPSD	ICGC;COSMIC	9.540	Gain
Atypical_PIKK_ATM_ATM_ST	Q8IY92	SLX4	Q13315	ATM	T1476	L1472I	1472	Missense	distal	-4	no	9.318	9.545	EPSD	ICGC	9.540	Gain
Atypical_PIKK_ATM_ATM_ST	Q8IY92	SLX4	Q13315	ATM	S1608	T1602N	1602	Missense	distal	-6	no	9.763	9.716	EPSD	ICGC	9.540	Down-regulation
Atypical_PIKK_ATM_ATM_ST	Q8IY92	SLX4	Q13315	ATM	S1608	H1603R	1603	Missense	distal	-5	no	9.763	9.790	EPSD	ICGC	9.540	Up-regulation
Atypical_PIKK_ATM_ATM_ST	Q8IY92	SLX4	Q13315	ATM	S1610	H1603R	1603	Missense	distal	-7	no	9.762	9.676	EPSD	ICGC	9.540	Down-regulation
Atypical_PIKK_ATM_ATM_ST	Q8IY92	SLX4	Q13315	ATM	S1681	P1682T	1682	Missense	proximal	1	no	10.439	5.432	EPSD	ICGC;COSMIC	9.540	Loss
Atypical_PIKK_ATM_ATM_ST	Q8IY92	SLX4	Q13315	ATM	S1716	S1712R	1712	Missense	distal	-4	no	14.699	13.889	EPSD;PhosphoSitePlus	ICGC;COSMIC	9.540	Down-regulation
Atypical_PIKK_ATM_ATM_ST	Q9UGP5	POLL	Q13315	ATM	S167	L166V	166	Missense	proximal	-1	no	10.198	9.909	EPSD	ICGC;COSMIC	9.540	Down-regulation
Atypical_PIKK_ATM_ATM_ST	Q9UGP5	POLL	Q13315	ATM	S177	A182E	182	Missense	distal	5	no	10.282	10.063	EPSD	ICGC	9.540	Down-regulation
Atypical_PIKK_ATM_ATM_ST	Q9UGP5	POLL	Q13315	ATM	T204	G201V	201	Missense	distal	-3	no	12.953	13.093	PhosphoSitePlus	ICGC;COSMIC;GDSC;CCLE	9.540	Up-regulation
Atypical_PIKK_ATM_ATM_ST	Q9UGP5	POLL	Q13315	ATM	T204	S199T	199	Missense	distal	-5	no	12.953	12.864	PhosphoSitePlus	ICGC;COSMIC	9.540	Down-regulation
Atypical_PIKK_ATM_ATM_ST	Q9UGP5	POLL	Q13315	ATM	S230	E224Q	224	Missense	distal	-6	no	10.644	10.419	EPSD	ICGC;COSMIC	9.540	Down-regulation
Atypical_PIKK_ATM_ATM_ST	Q9UGP5	POLL	Q13315	ATM	S526	S526N	526	Missense	central	0	yes	9.797	0.000	EPSD	ICGC;COSMIC	9.540	Loss
Atypical_PIKK_ATM_ATM_ST	Q9UGP5	POLL	Q13315	ATM	S526	M525I	525	Missense	proximal	-1	no	9.797	9.867	EPSD	ICGC;COSMIC	9.540	Up-regulation
Atypical_PIKK_ATM_ATM_ST	P60484	PTEN	Q13315	ATM	S113	D109H	109	Missense	distal	-4	no	12.108	11.432	EPSD;PhosphoSitePlus	ICGC;COSMIC	9.540	Down-regulation
Atypical_PIKK_ATM_ATM_ST	P60484	PTEN	Q13315	ATM	S113	H118D	118	Missense	distal	5	no	12.108	12.054	EPSD;PhosphoSitePlus	ICGC;COSMIC	9.540	Down-regulation
Atypical_PIKK_ATM_ATM_ST	P60484	PTEN	Q13315	ATM	S170	Y177C	177	Missense	distal	7	no	12.740	12.758	EPSD	ICGC;COSMIC	9.540	Up-regulation
Atypical_PIKK_ATM_ATM_ST	P60484	PTEN	Q13315	ATM	S170	Y177S	177	Missense	distal	7	no	12.740	12.706	EPSD	ICGC;COSMIC	9.540	Down-regulation
Atypical_PIKK_ATM_ATM_ST	P60484	PTEN	Q13315	ATM	S170	V175L	175	Missense	distal	5	no	12.740	12.692	EPSD	ICGC;COSMIC	9.540	Down-regulation
Atypical_PIKK_ATM_ATM_ST	P60484	PTEN	Q13315	ATM	T366	S360R	360	Missense	distal	-6	no	12.659	12.479	EPSD	ICGC	9.540	Down-regulation
Atypical_PIKK_ATM_ATM_ST	P23025	XPA	Q13315	ATM	S173	S173L	173	Missense	central	0	yes	13.775	0.000	EPSD;PhosphoSitePlus	ICGC;COSMIC	9.540	Loss
Atypical_PIKK_ATM_ATM_ST	P23025	XPA	Q13315	ATM	S196	V193I	193	Missense	distal	-3	no	15.823	16.074	PhosphoSitePlus;EPSD	ICGC	9.540	Up-regulation
Atypical_PIKK_ATM_ATM_ST	P23025	XPA	Q13315	ATM	S196	E198D	198	Missense	proximal	2	no	15.823	15.692	PhosphoSitePlus;EPSD	ICGC	9.540	Down-regulation
Atypical_PIKK_ATM_ATM_ST	P16220	CREB1	Q13315	ATM	S133	D140A	140	Missense	distal	7	no	11.625	11.647	PhosphoSitePlus;EPSD	ICGC;COSMIC	9.540	Up-regulation
Atypical_PIKK_ATM_ATM_ST	P16220	CREB1	Q13315	ATM	S156	E153G	153	Missense	distal	-3	no	9.858	10.295	EPSD	ICGC	9.540	Up-regulation
Atypical_PIKK_ATM_ATM_ST	P35637	FUS	Q13315	ATM	T7	D5Y	5	Missense	proximal	-2	no	11.741	11.870	EPSD	ICGC;COSMIC	9.540	Up-regulation
Atypical_PIKK_ATM_ATM_ST	P35637	FUS	Q13315	ATM	T11	D5Y	5	Missense	distal	-6	no	11.965	11.742	EPSD	ICGC;COSMIC	9.540	Down-regulation
Atypical_PIKK_ATM_ATM_ST	P35637	FUS	Q13315	ATM	T11	P18T	18	Missense	distal	7	no	11.965	11.962	EPSD	ICGC;COSMIC	9.540	Down-regulation
Atypical_PIKK_ATM_ATM_ST	P35637	FUS	Q13315	ATM	T19	P18T	18	Missense	proximal	-1	no	13.209	13.511	EPSD	ICGC;COSMIC	9.540	Up-regulation
Atypical_PIKK_ATM_ATM_ST	P35637	FUS	Q13315	ATM	T19	G24D	24	Missense	distal	5	no	13.209	13.117	EPSD	ICGC	9.540	Down-regulation
Atypical_PIKK_ATM_ATM_ST	P35637	FUS	Q13315	ATM	T19	P21S	21	Missense	proximal	2	no	13.209	13.664	EPSD	ICGC;COSMIC	9.540	Up-regulation
Atypical_PIKK_ATM_ATM_ST	P35637	FUS	Q13315	ATM	S26	G24D	24	Missense	proximal	-2	no	15.651	15.796	EPSD	ICGC	9.540	Up-regulation
Atypical_PIKK_ATM_ATM_ST	P35637	FUS	Q13315	ATM	S26	P21S	21	Missense	distal	-5	no	15.651	15.648	EPSD	ICGC;COSMIC	9.540	Down-regulation
Atypical_PIKK_ATM_ATM_ST	P35637	FUS	Q13315	ATM	S30	Q35H	35	Missense	distal	5	no	15.895	15.982	EPSD	ICGC	9.540	Up-regulation
Atypical_PIKK_ATM_ATM_ST	P35637	FUS	Q13315	ATM	S30	G24D	24	Missense	distal	-6	no	15.895	16.070	EPSD	ICGC	9.540	Up-regulation
Atypical_PIKK_ATM_ATM_ST	P35637	FUS	Q13315	ATM	S42	Q35H	35	Missense	distal	-7	no	14.065	13.951	PhosphoSitePlus	ICGC	9.540	Down-regulation
Atypical_PIKK_ATM_ATM_ST	P35637	FUS	Q13315	ATM	S42	G40C	40	Missense	proximal	-2	no	14.065	14.046	PhosphoSitePlus	ICGC	9.540	Down-regulation
Atypical_PIKK_ATM_ATM_ST	P35637	FUS	Q13315	ATM	S54	G59C	59	Missense	distal	5	no	9.518	9.567	EPSD	ICGC	9.540	Gain
Atypical_PIKK_ATM_ATM_ST	P35637	FUS	Q13315	ATM	S61	G59C	59	Missense	proximal	-2	no	15.640	15.621	EPSD	ICGC	9.540	Down-regulation
Atypical_PIKK_ATM_ATM_ST	P35637	FUS	Q13315	ATM	S84	S86T	86	Missense	proximal	2	no	16.268	16.006	EPSD	ICGC;COSMIC	9.540	Down-regulation
Atypical_PIKK_ATM_ATM_ST	P35637	FUS	Q13315	ATM	S84	Y81C	81	Missense	distal	-3	no	16.268	16.303	EPSD	ICGC;COSMIC	9.540	Up-regulation
Atypical_PIKK_ATM_ATM_ST	P35637	FUS	Q13315	ATM	S87	S86T	86	Missense	proximal	-1	no	13.480	13.491	EPSD	ICGC;COSMIC	9.540	Up-regulation
Atypical_PIKK_ATM_ATM_ST	P35637	FUS	Q13315	ATM	S87	Y81C	81	Missense	distal	-6	no	13.480	13.350	EPSD	ICGC;COSMIC	9.540	Down-regulation
Atypical_PIKK_ATM_ATM_ST	P35637	FUS	Q13315	ATM	S117	S120R	120	Missense	distal	3	no	15.378	15.563	EPSD	ICGC;COSMIC	9.540	Up-regulation
Atypical_PIKK_ATM_ATM_ST	P35637	FUS	Q13315	ATM	S277	D276E	276	Missense	proximal	-1	no	10.345	10.610	EPSD	ICGC;COSMIC	9.540	Up-regulation
Atypical_PIKK_ATM_ATM_ST	P35637	FUS	Q13315	ATM	S282	D276E	276	Missense	distal	-6	no	10.165	10.380	EPSD	ICGC;COSMIC	9.540	Up-regulation
Atypical_PIKK_ATM_ATM_ST	Q7Z6Z7	HUWE1	Q13315	ATM	T485	M491I	491	Missense	distal	6	no	14.849	14.837	EPSD	ICGC;COSMIC	9.540	Down-regulation
Atypical_PIKK_ATM_ATM_ST	Q7Z6Z7	HUWE1	Q13315	ATM	T485	E489D	489	Missense	distal	4	no	14.849	15.354	EPSD	ICGC;COSMIC	9.540	Up-regulation
Atypical_PIKK_ATM_ATM_ST	Q7Z6Z7	HUWE1	Q13315	ATM	S636	P641Q	641	Missense	distal	5	no	13.376	13.248	EPSD	ICGC	9.540	Down-regulation
Atypical_PIKK_ATM_ATM_ST	Q7Z6Z7	HUWE1	Q13315	ATM	S636	R629C	629	Missense	distal	-7	no	13.376	13.101	EPSD	ICGC;COSMIC	9.540	Down-regulation
Atypical_PIKK_ATM_ATM_ST	Q7Z6Z7	HUWE1	Q13315	ATM	T744	T744I	744	Missense	central	0	yes	15.443	0.000	EPSD	ICGC	9.540	Loss
Atypical_PIKK_ATM_ATM_ST	Q7Z6Z7	HUWE1	Q13315	ATM	S927	Q928K	928	Missense	proximal	1	no	14.403	7.554	EPSD;PhosphoSitePlus	ICGC;COSMIC	9.540	Loss
Atypical_PIKK_ATM_ATM_ST	Q7Z6Z7	HUWE1	Q13315	ATM	T1005	A1003S	1003	Missense	proximal	-2	no	12.495	12.683	EPSD	ICGC;COSMIC	9.540	Up-regulation
Atypical_PIKK_ATM_ATM_ST	Q7Z6Z7	HUWE1	Q13315	ATM	T1005	L1008F	1008	Missense	distal	3	no	12.495	12.795	EPSD	ICGC	9.540	Up-regulation
Atypical_PIKK_ATM_ATM_ST	Q7Z6Z7	HUWE1	Q13315	ATM	S1218	L1222M	1222	Missense	distal	4	no	10.342	10.261	EPSD	ICGC	9.540	Down-regulation
Atypical_PIKK_ATM_ATM_ST	Q7Z6Z7	HUWE1	Q13315	ATM	S1218	P1223T	1223	Missense	distal	5	no	10.342	10.144	EPSD	ICGC	9.540	Down-regulation
Atypical_PIKK_ATM_ATM_ST	Q7Z6Z7	HUWE1	Q13315	ATM	S1218	P1212H	1212	Missense	distal	-6	no	10.342	10.222	EPSD	ICGC;COSMIC	9.540	Down-regulation
Atypical_PIKK_ATM_ATM_ST	Q7Z6Z7	HUWE1	Q13315	ATM	S1370	E1371K	1371	Missense	proximal	1	no	10.535	9.583	EPSD	ICGC;COSMIC	9.540	Down-regulation
Atypical_PIKK_ATM_ATM_ST	Q7Z6Z7	HUWE1	Q13315	ATM	S1505	T1504P	1504	Missense	proximal	-1	no	10.056	9.754	EPSD	ICGC;COSMIC	9.540	Down-regulation
Atypical_PIKK_ATM_ATM_ST	Q7Z6Z7	HUWE1	Q13315	ATM	S1505	T1503A	1503	Missense	proximal	-2	no	10.056	9.956	EPSD	ICGC	9.540	Down-regulation
Atypical_PIKK_ATM_ATM_ST	Q7Z6Z7	HUWE1	Q13315	ATM	S1505	T1503K	1503	Missense	proximal	-2	no	10.056	9.749	EPSD	ICGC	9.540	Down-regulation
Atypical_PIKK_ATM_ATM_ST	Q7Z6Z7	HUWE1	Q13315	ATM	S1505	P1501S	1501	Missense	distal	-4	no	10.056	10.725	EPSD	ICGC	9.540	Up-regulation
Atypical_PIKK_ATM_ATM_ST	Q7Z6Z7	HUWE1	Q13315	ATM	S1707	S1707R	1707	Missense	central	0	yes	9.888	0.000	EPSD	ICGC;COSMIC	9.540	Loss
Atypical_PIKK_ATM_ATM_ST	Q7Z6Z7	HUWE1	Q13315	ATM	S1707	R1714H	1714	Missense	distal	7	no	9.888	9.882	EPSD	ICGC;COSMIC	9.540	Down-regulation
Atypical_PIKK_ATM_ATM_ST	Q7Z6Z7	HUWE1	Q13315	ATM	S1736	E1734G	1734	Missense	proximal	-2	no	9.702	9.079	EPSD	ICGC;COSMIC	9.540	Loss
Atypical_PIKK_ATM_ATM_ST	Q7Z6Z7	HUWE1	Q13315	ATM	S1736	E1738D	1738	Missense	proximal	2	no	9.702	9.571	EPSD	ICGC;COSMIC	9.540	Down-regulation
Atypical_PIKK_ATM_ATM_ST	Q7Z6Z7	HUWE1	Q13315	ATM	T2003	R1996C	1996	Missense	distal	-7	no	15.824	15.549	EPSD	ICGC;COSMIC	9.540	Down-regulation
Atypical_PIKK_ATM_ATM_ST	Q7Z6Z7	HUWE1	Q13315	ATM	S2011	Q2012K	2012	Missense	proximal	1	no	13.768	6.919	EPSD	ICGC	9.540	Loss
Atypical_PIKK_ATM_ATM_ST	Q7Z6Z7	HUWE1	Q13315	ATM	S2052	A2051D	2051	Missense	proximal	-1	no	9.649	9.755	EPSD	ICGC	9.540	Up-regulation
Atypical_PIKK_ATM_ATM_ST	Q7Z6Z7	HUWE1	Q13315	ATM	S2052	Q2057K	2057	Missense	distal	5	no	9.649	9.600	EPSD	ICGC;COSMIC	9.540	Down-regulation
Atypical_PIKK_ATM_ATM_ST	Q7Z6Z7	HUWE1	Q13315	ATM	S2052	G2059S	2059	Missense	distal	7	no	9.649	9.608	EPSD	ICGC;COSMIC;GDSC;CCLE	9.540	Down-regulation
Atypical_PIKK_ATM_ATM_ST	Q7Z6Z7	HUWE1	Q13315	ATM	S2275	E2276Q	2276	Missense	proximal	1	no	8.689	14.586	EPSD	ICGC;COSMIC	9.540	Gain
Atypical_PIKK_ATM_ATM_ST	Q7Z6Z7	HUWE1	Q13315	ATM	S2339	Q2340K	2340	Missense	proximal	1	no	16.456	9.607	EPSD;PhosphoSitePlus	ICGC;COSMIC	9.540	Down-regulation
Atypical_PIKK_ATM_ATM_ST	Q7Z6Z7	HUWE1	Q13315	ATM	S2339	Q2343H	2343	Missense	distal	4	no	16.456	16.540	EPSD;PhosphoSitePlus	ICGC;COSMIC	9.540	Up-regulation
Atypical_PIKK_ATM_ATM_ST	Q7Z6Z7	HUWE1	Q13315	ATM	S2339	G2332W	2332	Missense	distal	-7	no	16.456	16.380	EPSD;PhosphoSitePlus	ICGC;COSMIC	9.540	Down-regulation
Atypical_PIKK_ATM_ATM_ST	Q7Z6Z7	HUWE1	Q13315	ATM	S2391	A2393S	2393	Missense	proximal	2	no	13.767	14.349	EPSD	ICGC	9.540	Up-regulation
Atypical_PIKK_ATM_ATM_ST	Q7Z6Z7	HUWE1	Q13315	ATM	S2391	Q2397R	2397	Missense	distal	6	no	13.767	13.771	EPSD	ICGC;COSMIC	9.540	Up-regulation
Atypical_PIKK_ATM_ATM_ST	Q7Z6Z7	HUWE1	Q13315	ATM	S2477	D2473N	2473	Missense	distal	-4	no	12.054	11.129	EPSD	ICGC;COSMIC	9.540	Down-regulation
Atypical_PIKK_ATM_ATM_ST	Q7Z6Z7	HUWE1	Q13315	ATM	S2477	P2472H	2472	Missense	distal	-5	no	12.054	12.098	EPSD	ICGC	9.540	Up-regulation
Atypical_PIKK_ATM_ATM_ST	Q7Z6Z7	HUWE1	Q13315	ATM	S2508	A2502T	2502	Missense	distal	-6	no	11.610	11.562	EPSD	ICGC;COSMIC	9.540	Down-regulation
Atypical_PIKK_ATM_ATM_ST	Q7Z6Z7	HUWE1	Q13315	ATM	T2540	T2537A	2537	Missense	distal	-3	no	12.010	11.633	EPSD	ICGC;COSMIC	9.540	Down-regulation
Atypical_PIKK_ATM_ATM_ST	Q7Z6Z7	HUWE1	Q13315	ATM	T2540	L2539I	2539	Missense	proximal	-1	no	12.010	11.925	EPSD	ICGC	9.540	Down-regulation
Atypical_PIKK_ATM_ATM_ST	Q7Z6Z7	HUWE1	Q13315	ATM	S2546	L2539I	2539	Missense	distal	-7	no	12.023	11.946	EPSD	ICGC	9.540	Down-regulation
Atypical_PIKK_ATM_ATM_ST	Q7Z6Z7	HUWE1	Q13315	ATM	S2619	R2618S	2618	Missense	proximal	-1	no	9.348	9.722	EPSD	ICGC;COSMIC	9.540	Gain
Atypical_PIKK_ATM_ATM_ST	Q7Z6Z7	HUWE1	Q13315	ATM	S2619	E2622A	2622	Missense	distal	3	no	9.348	9.579	EPSD	ICGC;COSMIC	9.540	Gain
Atypical_PIKK_ATM_ATM_ST	Q7Z6Z7	HUWE1	Q13315	ATM	S2636	A2638V	2638	Missense	proximal	2	no	14.756	14.447	EPSD;PhosphoSitePlus	ICGC;COSMIC	9.540	Down-regulation
Atypical_PIKK_ATM_ATM_ST	Q7Z6Z7	HUWE1	Q13315	ATM	S2636	A2638E	2638	Missense	proximal	2	no	14.756	15.850	EPSD;PhosphoSitePlus	ICGC	9.540	Up-regulation
Atypical_PIKK_ATM_ATM_ST	Q7Z6Z7	HUWE1	Q13315	ATM	T2640	A2638E	2638	Missense	proximal	-2	no	9.524	9.893	EPSD	ICGC	9.540	Gain
Atypical_PIKK_ATM_ATM_ST	Q7Z6Z7	HUWE1	Q13315	ATM	S2726	N2727D	2727	Missense	proximal	1	no	5.894	9.725	EPSD	ICGC	9.540	Gain
Atypical_PIKK_ATM_ATM_ST	Q7Z6Z7	HUWE1	Q13315	ATM	T2821	E2819Q	2819	Missense	proximal	-2	no	13.010	12.706	EPSD	ICGC;COSMIC	9.540	Down-regulation
Atypical_PIKK_ATM_ATM_ST	Q7Z6Z7	HUWE1	Q13315	ATM	T2821	T2820K	2820	Missense	proximal	-1	no	13.010	12.808	EPSD	ICGC;COSMIC	9.540	Down-regulation
Atypical_PIKK_ATM_ATM_ST	Q7Z6Z7	HUWE1	Q13315	ATM	S2826	E2819Q	2819	Missense	distal	-7	no	9.681	9.126	EPSD	ICGC;COSMIC	9.540	Loss
Atypical_PIKK_ATM_ATM_ST	Q7Z6Z7	HUWE1	Q13315	ATM	S2826	T2820K	2820	Missense	distal	-6	no	9.681	9.637	EPSD	ICGC;COSMIC	9.540	Down-regulation
Atypical_PIKK_ATM_ATM_ST	Q7Z6Z7	HUWE1	Q13315	ATM	S2835	A2839V	2839	Missense	distal	4	no	9.475	10.128	EPSD	ICGC;COSMIC	9.540	Gain
Atypical_PIKK_ATM_ATM_ST	Q7Z6Z7	HUWE1	Q13315	ATM	S2850	T2846K	2846	Missense	distal	-4	no	12.588	12.278	EPSD	ICGC;COSMIC	9.540	Down-regulation
Atypical_PIKK_ATM_ATM_ST	Q7Z6Z7	HUWE1	Q13315	ATM	S2923	T2928N	2928	Missense	distal	5	no	10.474	10.465	EPSD	ICGC	9.540	Down-regulation
Atypical_PIKK_ATM_ATM_ST	Q7Z6Z7	HUWE1	Q13315	ATM	S2953	P2958L	2958	Missense	distal	5	no	12.804	12.787	EPSD	ICGC;COSMIC	9.540	Down-regulation
Atypical_PIKK_ATM_ATM_ST	Q7Z6Z7	HUWE1	Q13315	ATM	S2953	P2947T	2947	Missense	distal	-6	no	12.804	12.794	EPSD	ICGC;COSMIC	9.540	Down-regulation
Atypical_PIKK_ATM_ATM_ST	Q7Z6Z7	HUWE1	Q13315	ATM	S2953	P2947L	2947	Missense	distal	-6	no	12.804	12.575	EPSD	ICGC;COSMIC;GDSC;CCLE	9.540	Down-regulation
Atypical_PIKK_ATM_ATM_ST	Q7Z6Z7	HUWE1	Q13315	ATM	S2963	P2958L	2958	Missense	distal	-5	no	9.705	9.724	EPSD	ICGC;COSMIC	9.540	Up-regulation
Atypical_PIKK_ATM_ATM_ST	Q7Z6Z7	HUWE1	Q13315	ATM	S2963	S2963C	2963	Missense	central	0	yes	9.705	0.000	EPSD	ICGC;COSMIC	9.540	Loss
Atypical_PIKK_ATM_ATM_ST	Q7Z6Z7	HUWE1	Q13315	ATM	S3018	T3015N	3015	Missense	distal	-3	no	11.802	11.843	EPSD	ICGC	9.540	Up-regulation
Atypical_PIKK_ATM_ATM_ST	Q7Z6Z7	HUWE1	Q13315	ATM	S3018	P3012T	3012	Missense	distal	-6	no	11.802	11.792	EPSD	ICGC;COSMIC	9.540	Down-regulation
Atypical_PIKK_ATM_ATM_ST	Q7Z6Z7	HUWE1	Q13315	ATM	S3052	P3058H	3058	Missense	distal	6	no	9.943	9.921	EPSD	ICGC;COSMIC	9.540	Down-regulation
Atypical_PIKK_ATM_ATM_ST	Q7Z6Z7	HUWE1	Q13315	ATM	S3127	A3120T	3120	Missense	distal	-7	no	9.827	9.843	EPSD	ICGC;COSMIC;CCLE	9.540	Up-regulation
Atypical_PIKK_ATM_ATM_ST	Q7Z6Z7	HUWE1	Q13315	ATM	S3373	Q3378R	3378	Missense	distal	5	no	10.639	10.751	EPSD	ICGC	9.540	Up-regulation
Atypical_PIKK_ATM_ATM_ST	Q7Z6Z7	HUWE1	Q13315	ATM	S3373	A3371T	3371	Missense	proximal	-2	no	10.639	10.739	EPSD	ICGC;COSMIC	9.540	Up-regulation
Atypical_PIKK_ATM_ATM_ST	Q7Z6Z7	HUWE1	Q13315	ATM	S3377	Q3378R	3378	Missense	proximal	1	no	16.606	9.955	EPSD;PhosphoSitePlus	ICGC	9.540	Down-regulation
Atypical_PIKK_ATM_ATM_ST	Q7Z6Z7	HUWE1	Q13315	ATM	S3377	S3381C	3381	Missense	distal	4	no	16.606	17.116	EPSD;PhosphoSitePlus	ICGC;COSMIC	9.540	Up-regulation
Atypical_PIKK_ATM_ATM_ST	Q7Z6Z7	HUWE1	Q13315	ATM	S3377	A3371T	3371	Missense	distal	-6	no	16.606	16.558	EPSD;PhosphoSitePlus	ICGC;COSMIC	9.540	Down-regulation
Atypical_PIKK_ATM_ATM_ST	Q7Z6Z7	HUWE1	Q13315	ATM	S3422	G3416S	3416	Missense	distal	-6	no	10.803	11.004	EPSD	ICGC;COSMIC	9.540	Up-regulation
Atypical_PIKK_ATM_ATM_ST	Q7Z6Z7	HUWE1	Q13315	ATM	S3422	P3423T	3423	Missense	proximal	1	no	10.803	5.796	EPSD	ICGC;COSMIC	9.540	Loss
Atypical_PIKK_ATM_ATM_ST	Q7Z6Z7	HUWE1	Q13315	ATM	S3662	Q3657K	3657	Missense	distal	-5	no	9.935	9.985	EPSD	ICGC	9.540	Up-regulation
Atypical_PIKK_ATM_ATM_ST	Q7Z6Z7	HUWE1	Q13315	ATM	S3662	P3663H	3663	Missense	proximal	1	no	9.935	-0.172	EPSD	ICGC;COSMIC	9.540	Loss
Atypical_PIKK_ATM_ATM_ST	Q7Z6Z7	HUWE1	Q13315	ATM	S3695	R3698Q	3698	Missense	distal	3	no	13.868	13.766	EPSD;PhosphoSitePlus	ICGC;COSMIC	9.540	Down-regulation
Atypical_PIKK_ATM_ATM_ST	Q7Z6Z7	HUWE1	Q13315	ATM	S3695	P3699S	3699	Missense	distal	4	no	13.868	13.746	EPSD;PhosphoSitePlus	ICGC;COSMIC	9.540	Down-regulation
Atypical_PIKK_ATM_ATM_ST	Q7Z6Z7	HUWE1	Q13315	ATM	S3794	E3795Q	3795	Missense	proximal	1	no	8.002	13.898	EPSD	ICGC;COSMIC	9.540	Gain
Atypical_PIKK_ATM_ATM_ST	Q7Z6Z7	HUWE1	Q13315	ATM	S3797	E3795Q	3795	Missense	proximal	-2	no	14.874	14.569	PhosphoSitePlus;EPSD	ICGC;COSMIC	9.540	Down-regulation
Atypical_PIKK_ATM_ATM_ST	Q7Z6Z7	HUWE1	Q13315	ATM	S3797	R3804Q	3804	Missense	distal	7	no	14.874	14.849	PhosphoSitePlus;EPSD	ICGC;COSMIC	9.540	Down-regulation
Atypical_PIKK_ATM_ATM_ST	Q7Z6Z7	HUWE1	Q13315	ATM	S3799	E3795Q	3795	Missense	distal	-4	no	10.218	9.495	EPSD	ICGC;COSMIC	9.540	Loss
Atypical_PIKK_ATM_ATM_ST	Q7Z6Z7	HUWE1	Q13315	ATM	S3799	R3804Q	3804	Missense	distal	5	no	10.218	10.106	EPSD	ICGC;COSMIC	9.540	Down-regulation
Atypical_PIKK_ATM_ATM_ST	Q7Z6Z7	HUWE1	Q13315	ATM	S3808	R3804Q	3804	Missense	distal	-4	no	11.029	11.394	EPSD	ICGC;COSMIC	9.540	Up-regulation
Atypical_PIKK_ATM_ATM_ST	Q7Z6Z7	HUWE1	Q13315	ATM	S3808	D3813E	3813	Missense	distal	5	no	11.029	10.771	EPSD	ICGC;COSMIC	9.540	Down-regulation
Atypical_PIKK_ATM_ATM_ST	Q7Z6Z7	HUWE1	Q13315	ATM	S3919	P3915H	3915	Missense	distal	-4	no	9.662	9.652	EPSD	ICGC	9.540	Down-regulation
Atypical_PIKK_ATM_ATM_ST	Q7Z6Z7	HUWE1	Q13315	ATM	S3919	P3920H	3920	Missense	proximal	1	no	9.662	-0.445	EPSD	ICGC	9.540	Loss
Atypical_PIKK_ATM_ATM_ST	Q7Z6Z7	HUWE1	Q13315	ATM	S3947	S3941F	3941	Missense	distal	-6	no	10.646	10.115	EPSD	ICGC	9.540	Down-regulation
Atypical_PIKK_ATM_ATM_ST	Q7Z6Z7	HUWE1	Q13315	ATM	S4070	M4077V	4077	Missense	distal	7	no	10.787	10.802	EPSD	ICGC;COSMIC	9.540	Up-regulation
Atypical_PIKK_ATM_ATM_ST	Q7Z6Z7	HUWE1	Q13315	ATM	S4070	N4075S	4075	Missense	distal	5	no	10.787	10.812	EPSD	ICGC;COSMIC	9.540	Up-regulation
Atypical_PIKK_ATM_ATM_ST	Q7Z6Z7	HUWE1	Q13315	ATM	S4070	R4063L	4063	Missense	distal	-7	no	10.787	10.598	EPSD	ICGC;COSMIC	9.540	Down-regulation
Atypical_PIKK_ATM_ATM_ST	Q15648	MED1	Q13315	ATM	S387	R386Q	386	Missense	proximal	-1	no	9.466	9.774	EPSD	ICGC	9.540	Gain
Atypical_PIKK_ATM_ATM_ST	Q15648	MED1	Q13315	ATM	S387	P383Q	383	Missense	distal	-4	no	9.466	9.691	EPSD	ICGC	9.540	Gain
Atypical_PIKK_ATM_ATM_ST	Q15648	MED1	Q13315	ATM	S434	L437R	437	Missense	distal	3	no	11.174	11.077	EPSD	ICGC;COSMIC	9.540	Down-regulation
Atypical_PIKK_ATM_ATM_ST	Q15648	MED1	Q13315	ATM	S599	F595S	595	Missense	distal	-4	no	15.395	16.794	EPSD	ICGC;COSMIC	9.540	Up-regulation
Atypical_PIKK_ATM_ATM_ST	Q15648	MED1	Q13315	ATM	S743	P749L	749	Missense	distal	6	no	13.731	13.685	EPSD	ICGC;COSMIC	9.540	Down-regulation
Atypical_PIKK_ATM_ATM_ST	Q15648	MED1	Q13315	ATM	S743	P748R	748	Missense	distal	5	no	13.731	13.715	EPSD	ICGC	9.540	Down-regulation
Atypical_PIKK_ATM_ATM_ST	Q15648	MED1	Q13315	ATM	S816	S823C	823	Missense	distal	7	no	14.078	14.130	EPSD;PhosphoSitePlus	ICGC;COSMIC	9.540	Up-regulation
Atypical_PIKK_ATM_ATM_ST	Q15648	MED1	Q13315	ATM	S872	F865V	865	Missense	distal	-7	no	15.569	15.919	PhosphoSitePlus;EPSD	ICGC;COSMIC	9.540	Up-regulation
Atypical_PIKK_ATM_ATM_ST	Q15648	MED1	Q13315	ATM	S887	D891Y	891	Missense	distal	4	no	16.742	16.837	EPSD;PhosphoSitePlus	ICGC;COSMIC	9.540	Up-regulation
Atypical_PIKK_ATM_ATM_ST	Q15648	MED1	Q13315	ATM	S1049	T1051I	1051	Missense	proximal	2	no	15.150	14.727	EPSD	ICGC;COSMIC	9.540	Down-regulation
Atypical_PIKK_ATM_ATM_ST	Q15648	MED1	Q13315	ATM	T1051	T1051I	1051	Missense	central	0	yes	9.640	0.000	EPSD	ICGC;COSMIC	9.540	Loss
Atypical_PIKK_ATM_ATM_ST	Q15648	MED1	Q13315	ATM	S1092	S1096N	1096	Missense	distal	4	no	10.245	10.373	EPSD	ICGC	9.540	Up-regulation
Atypical_PIKK_ATM_ATM_ST	Q15648	MED1	Q13315	ATM	S1156	H1161N	1161	Missense	distal	5	no	10.439	10.274	EPSD	ICGC	9.540	Down-regulation
Atypical_PIKK_ATM_ATM_ST	Q15648	MED1	Q13315	ATM	S1192	S1192F	1192	Missense	central	0	yes	10.689	0.000	EPSD	ICGC;GDSC;CCLE	9.540	Loss
Atypical_PIKK_ATM_ATM_ST	Q15648	MED1	Q13315	ATM	S1196	S1192F	1192	Missense	distal	-4	no	9.858	8.460	EPSD	ICGC;GDSC;CCLE	9.540	Loss
Atypical_PIKK_ATM_ATM_ST	Q15648	MED1	Q13315	ATM	S1207	P1208Q	1208	Missense	proximal	1	no	8.673	13.475	EPSD	ICGC	9.540	Gain
Atypical_PIKK_ATM_ATM_ST	Q15648	MED1	Q13315	ATM	S1223	P1224L	1224	Missense	proximal	1	no	9.627	8.073	EPSD	ICGC;COSMIC	9.540	Loss
Atypical_PIKK_ATM_ATM_ST	Q15648	MED1	Q13315	ATM	S1256	S1251Y	1251	Missense	distal	-5	no	13.636	13.660	EPSD	ICGC	9.540	Up-regulation
Atypical_PIKK_ATM_ATM_ST	Q15648	MED1	Q13315	ATM	S1276	S1269F	1269	Missense	distal	-7	no	10.082	9.252	EPSD	ICGC;COSMIC	9.540	Loss
Atypical_PIKK_ATM_ATM_ST	Q15648	MED1	Q13315	ATM	S1283	N1285K	1285	Missense	proximal	2	no	13.483	13.304	EPSD	ICGC	9.540	Down-regulation
Atypical_PIKK_ATM_ATM_ST	Q15648	MED1	Q13315	ATM	S1417	K1412R	1412	Missense	distal	-5	no	10.152	10.311	EPSD	ICGC;COSMIC	9.540	Up-regulation
Atypical_PIKK_ATM_ATM_ST	Q15648	MED1	Q13315	ATM	S1465	E1464K	1464	Missense	proximal	-1	no	11.512	11.110	EPSD	ICGC	9.540	Down-regulation
Atypical_PIKK_ATM_ATM_ST	Q15648	MED1	Q13315	ATM	S1467	E1464K	1464	Missense	distal	-3	no	9.794	9.861	EPSD	ICGC	9.540	Up-regulation
Atypical_PIKK_ATM_ATM_ST	Q15648	MED1	Q13315	ATM	S1536	S1539C	1539	Missense	distal	3	no	10.601	11.022	EPSD	ICGC;COSMIC	9.540	Up-regulation
Atypical_PIKK_ATM_ATM_ST	Q15648	MED1	Q13315	ATM	S1561	D1555E	1555	Missense	distal	-6	no	11.373	11.587	EPSD	ICGC	9.540	Up-regulation
Atypical_PIKK_ATM_ATM_ST	Q15648	MED1	Q13315	ATM	S1561	S1561R	1561	Missense	central	0	yes	11.373	0.000	EPSD	ICGC;COSMIC	9.540	Loss
Atypical_PIKK_ATM_ATM_ST	P07900	HSP90AA1	Q13315	ATM	T5	E3K	3	Missense	proximal	-2	no	12.174	11.598	EPSD;PhosphoSitePlus	ICGC	9.540	Down-regulation
Atypical_PIKK_ATM_ATM_ST	P07900	HSP90AA1	Q13315	ATM	T7	E3K	3	Missense	distal	-4	no	12.073	11.101	PhosphoSitePlus;EPSD	ICGC	9.540	Down-regulation
Atypical_PIKK_ATM_ATM_ST	P07900	HSP90AA1	Q13315	ATM	S53	E47K	47	Missense	distal	-6	no	9.606	9.305	EPSD	ICGC;COSMIC;CCLE	9.540	Loss
Atypical_PIKK_ATM_ATM_ST	P07900	HSP90AA1	Q13315	ATM	S53	E47Q	47	Missense	distal	-6	no	9.606	9.381	EPSD	ICGC;COSMIC	9.540	Loss
Atypical_PIKK_ATM_ATM_ST	P07900	HSP90AA1	Q13315	ATM	S63	D66Y	66	Missense	distal	3	no	10.340	10.398	EPSD	ICGC;COSMIC	9.540	Up-regulation
Atypical_PIKK_ATM_ATM_ST	P07900	HSP90AA1	Q13315	ATM	S63	T65K	65	Missense	proximal	2	no	10.340	9.782	EPSD	ICGC	9.540	Down-regulation
Atypical_PIKK_ATM_ATM_ST	P07900	HSP90AA1	Q13315	ATM	S165	A161P	161	Missense	distal	-4	no	9.812	9.652	EPSD	ICGC;COSMIC	9.540	Down-regulation
Atypical_PIKK_ATM_ATM_ST	P07900	HSP90AA1	Q13315	ATM	S165	S165L	165	Missense	central	0	yes	9.812	0.000	EPSD	ICGC;COSMIC	9.540	Loss
Atypical_PIKK_ATM_ATM_ST	P07900	HSP90AA1	Q13315	ATM	S165	S164Y	164	Missense	proximal	-1	no	9.812	9.763	EPSD	ICGC	9.540	Down-regulation
Atypical_PIKK_ATM_ATM_ST	P07900	HSP90AA1	Q13315	ATM	S211	G215A	215	Missense	distal	4	no	13.224	12.748	EPSD	ICGC;COSMIC	9.540	Down-regulation
Atypical_PIKK_ATM_ATM_ST	P07900	HSP90AA1	Q13315	ATM	S211	E205D	205	Missense	distal	-6	no	13.224	13.010	EPSD	ICGC;COSMIC	9.540	Down-regulation
Atypical_PIKK_ATM_ATM_ST	P07900	HSP90AA1	Q13315	ATM	S211	S211F	211	Missense	central	0	yes	13.224	0.000	EPSD	ICGC;COSMIC	9.540	Loss
Atypical_PIKK_ATM_ATM_ST	P07900	HSP90AA1	Q13315	ATM	S211	V207A	207	Missense	distal	-4	no	13.224	13.704	EPSD	ICGC;COSMIC	9.540	Up-regulation
Atypical_PIKK_ATM_ATM_ST	P07900	HSP90AA1	Q13315	ATM	S252	K245E	245	Missense	distal	-7	no	9.817	10.485	EPSD	ICGC;COSMIC	9.540	Up-regulation
Atypical_PIKK_ATM_ATM_ST	P07900	HSP90AA1	Q13315	ATM	S315	G310R	310	Missense	distal	-5	no	11.255	11.276	EPSD	ICGC;COSMIC	9.540	Up-regulation
Atypical_PIKK_ATM_ATM_ST	P07900	HSP90AA1	Q13315	ATM	S315	D322N	322	Missense	distal	7	no	11.255	11.262	EPSD	ICGC;COSMIC	9.540	Up-regulation
Atypical_PIKK_ATM_ATM_ST	P07900	HSP90AA1	Q13315	ATM	S315	F312L	312	Missense	distal	-3	no	11.255	10.392	EPSD	ICGC;COSMIC	9.540	Down-regulation
Atypical_PIKK_ATM_ATM_ST	P07900	HSP90AA1	Q13315	ATM	S453	R456Q	456	Missense	distal	3	no	13.946	13.844	EPSD	ICGC;COSMIC	9.540	Down-regulation
Atypical_PIKK_ATM_ATM_ST	P07900	HSP90AA1	Q13315	ATM	T545	L541S	541	Missense	distal	-4	no	9.057	9.996	EPSD	ICGC;COSMIC	9.540	Gain
Atypical_PIKK_ATM_ATM_ST	P07900	HSP90AA1	Q13315	ATM	S595	I599V	599	Missense	distal	4	no	11.393	11.036	EPSD	ICGC;COSMIC	9.540	Down-regulation
Atypical_PIKK_ATM_ATM_ST	P07900	HSP90AA1	Q13315	ATM	S595	S595F	595	Missense	central	0	yes	11.393	0.000	EPSD	ICGC;COSMIC	9.540	Loss
Atypical_PIKK_ATM_ATM_ST	P07900	HSP90AA1	Q13315	ATM	S595	V600I	600	Missense	distal	5	no	11.393	11.390	EPSD	ICGC;COSMIC	9.540	Down-regulation
Atypical_PIKK_ATM_ATM_ST	Q9BQ15	NABP2	Q13315	ATM	T117	A120S	120	Missense	distal	3	no	12.515	12.459	PhosphoSitePlus	ICGC	9.540	Down-regulation
Atypical_PIKK_ATM_ATM_ST	Q9BQ15	NABP2	Q13315	ATM	S144	S147F	147	Missense	distal	3	no	9.338	9.920	EPSD	ICGC;COSMIC	9.540	Gain
Atypical_PIKK_ATM_ATM_ST	P46527	CDKN1B	Q13315	ATM	S106	V109G	109	Missense	distal	3	no	13.844	13.631	EPSD	ICGC;COSMIC	9.540	Down-regulation
Atypical_PIKK_ATM_ATM_ST	P46527	CDKN1B	Q13315	ATM	S106	C99W	99	Missense	distal	-7	no	13.844	13.930	EPSD	ICGC;COSMIC	9.540	Up-regulation
Atypical_PIKK_ATM_ATM_ST	P46527	CDKN1B	Q13315	ATM	S106	P102T	102	Missense	distal	-4	no	13.844	14.131	EPSD	ICGC;COSMIC	9.540	Up-regulation
Atypical_PIKK_ATM_ATM_ST	P46527	CDKN1B	Q13315	ATM	S140	S138W	138	Missense	proximal	-2	no	16.385	15.891	PhosphoSitePlus	ICGC	9.540	Down-regulation
Atypical_PIKK_ATM_ATM_ST	P38398	BRCA1	Q13315	ATM	S114	D120G	120	Missense	distal	6	no	11.197	11.200	EPSD	ICGC;COSMIC	9.540	Up-regulation
Atypical_PIKK_ATM_ATM_ST	P38398	BRCA1	Q13315	ATM	S114	H117N	117	Missense	distal	3	no	11.197	11.174	EPSD	ICGC;COSMIC	9.540	Down-regulation
Atypical_PIKK_ATM_ATM_ST	P38398	BRCA1	Q13315	ATM	S324	S324C	324	Missense	central	0	yes	10.337	0.000	EPSD	ICGC;COSMIC	9.540	Loss
Atypical_PIKK_ATM_ATM_ST	P38398	BRCA1	Q13315	ATM	S632	N635K	635	Missense	distal	3	no	11.021	10.934	EPSD	ICGC	9.540	Down-regulation
Atypical_PIKK_ATM_ATM_ST	P38398	BRCA1	Q13315	ATM	S1143	T1149K	1149	Missense	distal	6	no	15.311	15.300	EPSD	ICGC	9.540	Down-regulation
Atypical_PIKK_ATM_ATM_ST	P38398	BRCA1	Q13315	ATM	S1174	E1167D	1167	Missense	distal	-7	no	9.587	9.009	EPSD	ICGC;COSMIC	9.540	Loss
Atypical_PIKK_ATM_ATM_ST	P38398	BRCA1	Q13315	ATM	S1191	H1197N	1197	Missense	distal	6	no	10.237	10.260	EPSD	ICGC;COSMIC	9.540	Up-regulation
Atypical_PIKK_ATM_ATM_ST	P38398	BRCA1	Q13315	ATM	S1212	L1216F	1216	Missense	distal	4	no	9.588	10.074	EPSD	ICGC;COSMIC	9.540	Up-regulation
Atypical_PIKK_ATM_ATM_ST	P38398	BRCA1	Q13315	ATM	S1218	L1216F	1216	Missense	proximal	-2	no	10.333	9.823	EPSD	ICGC;COSMIC	9.540	Down-regulation
Atypical_PIKK_ATM_ATM_ST	Q96KQ7	EHMT2	Q13315	ATM	S173	P174L	174	Missense	proximal	1	no	10.012	8.458	EPSD	ICGC;COSMIC	9.540	Loss
Atypical_PIKK_ATM_ATM_ST	Q96KQ7	EHMT2	Q13315	ATM	S379	E383A	383	Missense	distal	4	no	10.766	10.717	EPSD	ICGC;COSMIC	9.540	Down-regulation
Atypical_PIKK_ATM_ATM_ST	Q96KQ7	EHMT2	Q13315	ATM	S569	R575C	575	Missense	distal	6	no	16.412	16.358	PhosphoSitePlus	ICGC;COSMIC	9.540	Down-regulation
Atypical_PIKK_ATM_ATM_ST	P23919	DTYMK	Q13315	ATM	S88	V91L	91	Missense	distal	3	no	12.473	12.411	PhosphoSitePlus	ICGC;COSMIC	9.540	Down-regulation
Atypical_PIKK_ATM_ATM_ST	Q99708	RBBP8	Q13315	ATM	S163	P164Q	164	Missense	proximal	1	no	8.823	13.625	EPSD	ICGC;COSMIC	9.540	Gain
Atypical_PIKK_ATM_ATM_ST	Q99708	RBBP8	Q13315	ATM	S231	D226E	226	Missense	distal	-5	no	13.801	13.846	EPSD	ICGC;COSMIC	9.540	Up-regulation
Atypical_PIKK_ATM_ATM_ST	Q99708	RBBP8	Q13315	ATM	S231	T227I	227	Missense	distal	-4	no	13.801	13.472	EPSD	ICGC	9.540	Down-regulation
Atypical_PIKK_ATM_ATM_ST	Q99708	RBBP8	Q13315	ATM	S231	M235I	235	Missense	distal	4	no	13.801	14.203	EPSD	ICGC;COSMIC	9.540	Up-regulation
Atypical_PIKK_ATM_ATM_ST	Q99708	RBBP8	Q13315	ATM	S231	S231I	231	Missense	central	0	yes	13.801	0.000	EPSD	ICGC	9.540	Loss
Atypical_PIKK_ATM_ATM_ST	Q99708	RBBP8	Q13315	ATM	S233	D226E	226	Missense	distal	-7	no	11.621	12.199	EPSD	ICGC;COSMIC	9.540	Up-regulation
Atypical_PIKK_ATM_ATM_ST	Q99708	RBBP8	Q13315	ATM	S233	T227I	227	Missense	distal	-6	no	11.621	11.289	EPSD	ICGC	9.540	Down-regulation
Atypical_PIKK_ATM_ATM_ST	Q99708	RBBP8	Q13315	ATM	S233	M235I	235	Missense	proximal	2	no	11.621	11.993	EPSD	ICGC;COSMIC	9.540	Up-regulation
Atypical_PIKK_ATM_ATM_ST	Q99708	RBBP8	Q13315	ATM	S233	S231I	231	Missense	proximal	-2	no	11.621	10.931	EPSD	ICGC	9.540	Down-regulation
Atypical_PIKK_ATM_ATM_ST	Q99708	RBBP8	Q13315	ATM	S309	T315P	315	Missense	distal	6	no	10.016	10.015	EPSD	ICGC	9.540	Down-regulation
Atypical_PIKK_ATM_ATM_ST	Q99708	RBBP8	Q13315	ATM	S539	R536H	536	Missense	distal	-3	no	10.074	9.429	EPSD	ICGC;GDSC;CCLE	9.540	Loss
Atypical_PIKK_ATM_ATM_ST	Q99708	RBBP8	Q13315	ATM	S549	K547E	547	Missense	proximal	-2	no	9.375	9.951	EPSD	ICGC;COSMIC	9.540	Gain
Atypical_PIKK_ATM_ATM_ST	Q99708	RBBP8	Q13315	ATM	S555	S555A	555	Missense	central	0	yes	16.693	0.000	EPSD	ICGC	9.540	Loss
Atypical_PIKK_ATM_ATM_ST	Q99708	RBBP8	Q13315	ATM	S555	P550S	550	Missense	distal	-5	no	16.693	16.689	EPSD	ICGC	9.540	Down-regulation
Atypical_PIKK_ATM_ATM_ST	Q99708	RBBP8	Q13315	ATM	S555	G551W	551	Missense	distal	-4	no	16.693	16.195	EPSD	ICGC;COSMIC	9.540	Down-regulation
Atypical_PIKK_ATM_ATM_ST	Q99708	RBBP8	Q13315	ATM	S679	K682Q	682	Missense	distal	3	no	13.734	13.704	EPSD	ICGC;COSMIC	9.540	Down-regulation
Atypical_PIKK_ATM_ATM_ST	Q99708	RBBP8	Q13315	ATM	S679	D674Y	674	Missense	distal	-5	no	13.734	13.969	EPSD	ICGC	9.540	Up-regulation
Atypical_PIKK_ATM_ATM_ST	Q99708	RBBP8	Q13315	ATM	S679	G678D	678	Missense	proximal	-1	no	13.734	13.871	EPSD	ICGC;COSMIC	9.540	Up-regulation
Atypical_PIKK_ATM_ATM_ST	Q99708	RBBP8	Q13315	ATM	T859	S858F	858	Missense	proximal	-1	no	13.405	12.979	EPSD	ICGC;COSMIC	9.540	Down-regulation
Atypical_PIKK_ATM_ATM_ST	Q99708	RBBP8	Q13315	ATM	T859	R865G	865	Missense	distal	6	no	13.405	13.404	EPSD	ICGC;COSMIC	9.540	Down-regulation
Atypical_PIKK_ATM_ATM_ST	Q99708	RBBP8	Q13315	ATM	T859	G866D	866	Missense	distal	7	no	13.405	13.372	EPSD	ICGC	9.540	Down-regulation
Atypical_PIKK_ATM_ATM_ST	O75150	RNF40	Q13315	ATM	S114	C111F	111	Missense	distal	-3	no	14.381	15.285	EPSD;PhosphoSitePlus	ICGC	9.540	Up-regulation
Atypical_PIKK_ATM_ATM_ST	O75150	RNF40	Q13315	ATM	T127	Q128K	128	Missense	proximal	1	no	13.562	6.714	EPSD	ICGC;COSMIC	9.540	Loss
Atypical_PIKK_ATM_ATM_ST	O75150	RNF40	Q13315	ATM	S219	A226D	226	Missense	distal	7	no	10.983	10.960	EPSD	ICGC;COSMIC	9.540	Down-regulation
Atypical_PIKK_ATM_ATM_ST	O75150	RNF40	Q13315	ATM	S819	V821M	821	Missense	proximal	2	no	14.389	14.224	EPSD;PhosphoSitePlus	ICGC;COSMIC	9.540	Down-regulation
Atypical_PIKK_ATM_ATM_ST	O75150	RNF40	Q13315	ATM	S819	A823V	823	Missense	distal	4	no	14.389	15.042	EPSD;PhosphoSitePlus	ICGC	9.540	Up-regulation
Atypical_PIKK_ATM_ATM_ST	O75150	RNF40	Q13315	ATM	S853	L856R	856	Missense	distal	3	no	13.618	13.521	PhosphoSitePlus;EPSD	ICGC;COSMIC	9.540	Down-regulation
Atypical_PIKK_ATM_ATM_ST	O75150	RNF40	Q13315	ATM	S853	R852C	852	Missense	proximal	-1	no	13.618	13.792	PhosphoSitePlus;EPSD	ICGC	9.540	Up-regulation
Atypical_PIKK_ATM_ATM_ST	Q5VTR2	RNF20	Q13315	ATM	S28	G29W	29	Missense	proximal	1	no	9.751	3.620	EPSD	ICGC;COSMIC	9.540	Loss
Atypical_PIKK_ATM_ATM_ST	Q5VTR2	RNF20	Q13315	ATM	T85	D87Y	87	Missense	proximal	2	no	10.867	9.627	EPSD	ICGC	9.540	Down-regulation
Atypical_PIKK_ATM_ATM_ST	Q5VTR2	RNF20	Q13315	ATM	T85	L91F	91	Missense	distal	6	no	10.867	10.848	EPSD	ICGC	9.540	Down-regulation
Atypical_PIKK_ATM_ATM_ST	Q5VTR2	RNF20	Q13315	ATM	S262	S269Y	269	Missense	distal	7	no	10.393	10.427	EPSD	ICGC	9.540	Up-regulation
Atypical_PIKK_ATM_ATM_ST	Q5VTR2	RNF20	Q13315	ATM	S522	E527D	527	Missense	distal	5	no	15.545	15.802	EPSD;PhosphoSitePlus	ICGC	9.540	Up-regulation
Atypical_PIKK_ATM_ATM_ST	Q5VTR2	RNF20	Q13315	ATM	S522	S517I	517	Missense	distal	-5	no	15.545	15.660	EPSD;PhosphoSitePlus	ICGC	9.540	Up-regulation
Atypical_PIKK_ATM_ATM_ST	Q5VTR2	RNF20	Q13315	ATM	S522	S515N	515	Missense	distal	-7	no	15.545	15.359	EPSD;PhosphoSitePlus	ICGC;COSMIC	9.540	Down-regulation
Atypical_PIKK_ATM_ATM_ST	Q5VTR2	RNF20	Q13315	ATM	S553	D556V	556	Missense	distal	3	no	14.520	14.680	EPSD	ICGC;COSMIC	9.540	Up-regulation
Atypical_PIKK_ATM_ATM_ST	P14618	PKM	Q13315	ATM	T15	Q14E	14	Missense	proximal	-1	no	15.755	16.033	EPSD	ICGC;COSMIC;GDSC;CCLE	9.540	Up-regulation
Atypical_PIKK_ATM_ATM_ST	P14618	PKM	Q13315	ATM	T15	Q14K	14	Missense	proximal	-1	no	15.755	15.630	EPSD	ICGC;COSMIC	9.540	Down-regulation
Atypical_PIKK_ATM_ATM_ST	P14618	PKM	Q13315	ATM	S55	R56Q	56	Missense	proximal	1	no	6.772	13.424	EPSD	ICGC;COSMIC	9.540	Gain
Atypical_PIKK_ATM_ATM_ST	O15355	PPM1G	Q13315	ATM	S183	P181T	181	Missense	proximal	-2	no	14.208	14.357	PhosphoSitePlus	ICGC	9.540	Up-regulation
Atypical_PIKK_ATM_ATM_ST	O15355	PPM1G	Q13315	ATM	S183	G178C	178	Missense	distal	-5	no	14.208	14.246	PhosphoSitePlus	ICGC	9.540	Up-regulation
Atypical_PIKK_ATM_ATM_ST	O15355	PPM1G	Q13315	ATM	S325	A331E	331	Missense	distal	6	no	9.571	9.589	EPSD	ICGC	9.540	Up-regulation
Atypical_PIKK_ATM_ATM_ST	Q14839	CHD4	Q13315	ATM	S7	P8Q	8	Missense	proximal	1	no	8.791	13.593	EPSD	ICGC;COSMIC	9.540	Gain
Atypical_PIKK_ATM_ATM_ST	Q14839	CHD4	Q13315	ATM	S44	E47D	47	Missense	distal	3	no	9.402	9.761	EPSD	ICGC;COSMIC	9.540	Gain
Atypical_PIKK_ATM_ATM_ST	Q14839	CHD4	Q13315	ATM	S168	D164A	164	Missense	distal	-4	no	9.655	9.150	EPSD	ICGC;COSMIC	9.540	Loss
Atypical_PIKK_ATM_ATM_ST	Q14839	CHD4	Q13315	ATM	S182	P187S	187	Missense	distal	5	no	12.750	12.568	EPSD	ICGC;COSMIC	9.540	Down-regulation
Atypical_PIKK_ATM_ATM_ST	Q14839	CHD4	Q13315	ATM	S310	D313H	313	Missense	distal	3	no	11.814	11.854	EPSD	ICGC;COSMIC	9.540	Up-regulation
Atypical_PIKK_ATM_ATM_ST	Q14839	CHD4	Q13315	ATM	S515	P513H	513	Missense	proximal	-2	no	11.502	11.311	EPSD	ICGC;COSMIC	9.540	Down-regulation
Atypical_PIKK_ATM_ATM_ST	Q14839	CHD4	Q13315	ATM	S515	P513S	513	Missense	proximal	-2	no	11.502	11.739	EPSD	ICGC;COSMIC	9.540	Up-regulation
Atypical_PIKK_ATM_ATM_ST	Q14839	CHD4	Q13315	ATM	S1531	P1536L	1536	Missense	distal	5	no	13.042	13.025	EPSD	ICGC;COSMIC	9.540	Down-regulation
Atypical_PIKK_ATM_ATM_ST	Q14839	CHD4	Q13315	ATM	S1535	P1536L	1536	Missense	proximal	1	no	10.548	8.993	EPSD	ICGC;COSMIC	9.540	Loss
Atypical_PIKK_ATM_ATM_ST	Q9NQS1	AVEN	Q13315	ATM	S268	S261R	261	Missense	distal	-7	no	12.284	11.885	EPSD	ICGC	9.540	Down-regulation
Atypical_PIKK_ATM_ATM_ST	Q9NQS1	AVEN	Q13315	ATM	S308	P304T	304	Missense	distal	-4	no	14.642	14.928	PhosphoSitePlus;EPSD	ICGC	9.540	Up-regulation
Atypical_PIKK_ATM_ATM_ST	Q9NQS1	AVEN	Q13315	ATM	S308	Q306K	306	Missense	proximal	-2	no	14.642	14.371	PhosphoSitePlus;EPSD	ICGC	9.540	Down-regulation
Atypical_PIKK_ATM_ATM_ST	O00255	MEN1	Q13315	ATM	S399	E397K	397	Missense	proximal	-2	no	16.788	16.212	EPSD	ICGC	9.540	Down-regulation
Atypical_PIKK_ATM_ATM_ST	O00255	MEN1	Q13315	ATM	S399	G396V	396	Missense	distal	-3	no	16.788	16.928	EPSD	ICGC;COSMIC	9.540	Up-regulation
Atypical_PIKK_ATM_ATM_ST	O00255	MEN1	Q13315	ATM	T402	E397K	397	Missense	distal	-5	no	13.866	13.948	EPSD	ICGC	9.540	Up-regulation
Atypical_PIKK_ATM_ATM_ST	O00255	MEN1	Q13315	ATM	T402	G396V	396	Missense	distal	-6	no	13.866	13.811	EPSD	ICGC;COSMIC	9.540	Down-regulation
Atypical_PIKK_ATM_ATM_ST	O00255	MEN1	Q13315	ATM	S404	E397K	397	Missense	distal	-7	no	14.283	13.615	EPSD	ICGC	9.540	Down-regulation
Atypical_PIKK_ATM_ATM_ST	Q8TAQ5	ZNF420	Q13315	ATM	S68	M72L	72	Missense	distal	4	no	13.803	13.884	PhosphoSitePlus	ICGC;COSMIC	9.540	Up-regulation
Atypical_PIKK_ATM_ATM_ST	Q8TAQ5	ZNF420	Q13315	ATM	S236	I233L	233	Missense	distal	-3	no	11.865	11.404	EPSD	ICGC;COSMIC	9.540	Down-regulation
Atypical_PIKK_ATM_ATM_ST	Q8TAQ5	ZNF420	Q13315	ATM	S236	R234H	234	Missense	proximal	-2	no	11.865	11.880	EPSD	ICGC;COSMIC	9.540	Up-regulation
Atypical_PIKK_ATM_ATM_ST	Q8TAQ5	ZNF420	Q13315	ATM	S404	K398R	398	Missense	distal	-6	no	12.116	12.049	EPSD	ICGC;COSMIC	9.540	Down-regulation
Atypical_PIKK_ATM_ATM_ST	Q8TAQ5	ZNF420	Q13315	ATM	S404	F400L	400	Missense	distal	-4	no	12.116	12.575	EPSD	ICGC	9.540	Up-regulation
Atypical_PIKK_ATM_ATM_ST	Q8TAQ5	ZNF420	Q13315	ATM	S488	R486L	486	Missense	proximal	-2	no	12.721	12.774	EPSD	ICGC	9.540	Up-regulation
Atypical_PIKK_ATM_ATM_ST	Q8TAQ5	ZNF420	Q13315	ATM	S488	I485V	485	Missense	distal	-3	no	12.721	12.470	EPSD	ICGC	9.540	Down-regulation
Atypical_PIKK_ATM_ATM_ST	Q8TAQ5	ZNF420	Q13315	ATM	S572	K566T	566	Missense	distal	-6	no	12.581	12.625	EPSD	ICGC;COSMIC	9.540	Up-regulation
Atypical_PIKK_ATM_ATM_ST	Q8TAQ5	ZNF420	Q13315	ATM	S572	R579P	579	Missense	distal	7	no	12.581	12.565	EPSD	ICGC;COSMIC	9.540	Down-regulation
Atypical_PIKK_ATM_ATM_ST	Q8TAQ5	ZNF420	Q13315	ATM	S572	Q578H	578	Missense	distal	6	no	12.581	12.570	EPSD	ICGC;COSMIC	9.540	Down-regulation
Atypical_PIKK_ATM_ATM_ST	Q9BXS6	NUSAP1	Q13315	ATM	S57	Q54K	54	Missense	distal	-3	no	12.261	12.204	EPSD	ICGC;COSMIC	9.540	Down-regulation
Atypical_PIKK_ATM_ATM_ST	Q9BXS6	NUSAP1	Q13315	ATM	S247	R249Q	249	Missense	proximal	2	no	13.192	13.888	EPSD	ICGC;COSMIC	9.540	Up-regulation
Atypical_PIKK_ATM_ATM_ST	Q9BXS6	NUSAP1	Q13315	ATM	S251	R249Q	249	Missense	proximal	-2	no	12.647	12.966	EPSD	ICGC;COSMIC	9.540	Up-regulation
Atypical_PIKK_ATM_ATM_ST	Q9BXS6	NUSAP1	Q13315	ATM	S363	N369T	369	Missense	distal	6	no	10.150	10.151	EPSD	ICGC	9.540	Up-regulation
Atypical_PIKK_ATM_ATM_ST	Q9NS91	RAD18	Q13315	ATM	T58	K52Q	52	Missense	distal	-6	no	13.645	13.722	EPSD	ICGC;COSMIC	9.540	Up-regulation
Atypical_PIKK_ATM_ATM_ST	Q9NS91	RAD18	Q13315	ATM	S146	S142R	142	Missense	distal	-4	no	11.295	10.484	EPSD	ICGC	9.540	Down-regulation
Atypical_PIKK_ATM_ATM_ST	Q9NS91	RAD18	Q13315	ATM	S403	H401Q	401	Missense	proximal	-2	no	13.694	13.997	PhosphoSitePlus	ICGC	9.540	Up-regulation
Atypical_PIKK_ATM_ATM_ST	Q9NS91	RAD18	Q13315	ATM	S409	P415T	415	Missense	distal	6	no	10.073	10.074	EPSD	ICGC	9.540	Up-regulation
Atypical_PIKK_ATM_ATM_ST	Q9NS91	RAD18	Q13315	ATM	S409	E411D	411	Missense	proximal	2	no	10.073	9.942	EPSD	ICGC	9.540	Down-regulation
Atypical_PIKK_ATM_ATM_ST	Q9NS91	RAD18	Q13315	ATM	S471	R476H	476	Missense	distal	5	no	10.322	10.296	EPSD	ICGC;COSMIC	9.540	Down-regulation
Atypical_PIKK_ATM_ATM_ST	Q9NS91	RAD18	Q13315	ATM	S471	D464N	464	Missense	distal	-7	no	10.322	10.358	EPSD	ICGC;COSMIC;CCLE	9.540	Up-regulation
Atypical_PIKK_ATM_ATM_ST	Q9NS91	RAD18	Q13315	ATM	S471	Q474K	474	Missense	distal	3	no	10.322	10.352	EPSD	ICGC;COSMIC	9.540	Up-regulation
Atypical_PIKK_ATM_ATM_ST	Q9NS91	RAD18	Q13315	ATM	S471	T478K	478	Missense	distal	7	no	10.322	10.328	EPSD	ICGC	9.540	Up-regulation
Atypical_PIKK_ATM_ATM_ST	P15927	RPA2	Q13315	ATM	T21	A17E	17	Missense	distal	-4	no	13.325	14.113	EPSD;PhosphoSitePlus	ICGC	9.540	Up-regulation
Atypical_PIKK_ATM_ATM_ST	P15927	RPA2	Q13315	ATM	S23	A17E	17	Missense	distal	-6	no	11.168	11.376	EPSD;PhosphoSitePlus	ICGC	9.540	Up-regulation
Atypical_PIKK_ATM_ATM_ST	P15927	RPA2	Q13315	ATM	S115	D111Y	111	Missense	distal	-4	no	9.648	8.552	EPSD	ICGC;COSMIC	9.540	Loss
Atypical_PIKK_ATM_ATM_ST	Q9UBU7	DBF4	Q13315	ATM	S84	N89S	89	Missense	distal	5	no	10.785	10.810	EPSD	ICGC;COSMIC	9.540	Up-regulation
Atypical_PIKK_ATM_ATM_ST	Q9UBU7	DBF4	Q13315	ATM	S84	I83V	83	Missense	proximal	-1	no	10.785	10.582	EPSD	ICGC;COSMIC	9.540	Down-regulation
Atypical_PIKK_ATM_ATM_ST	Q9UBU7	DBF4	Q13315	ATM	S84	D82Y	82	Missense	proximal	-2	no	10.785	10.914	EPSD	ICGC;COSMIC	9.540	Up-regulation
Atypical_PIKK_ATM_ATM_ST	Q9UBU7	DBF4	Q13315	ATM	S130	S126G	126	Missense	distal	-4	no	9.840	9.052	EPSD	ICGC;COSMIC	9.540	Loss
Atypical_PIKK_ATM_ATM_ST	Q9UBU7	DBF4	Q13315	ATM	S130	C135F	135	Missense	distal	5	no	9.840	9.920	EPSD	ICGC	9.540	Up-regulation
Atypical_PIKK_ATM_ATM_ST	Q9UBU7	DBF4	Q13315	ATM	S539	G532S	532	Missense	distal	-7	no	14.650	15.162	EPSD;PhosphoSitePlus	ICGC	9.540	Up-regulation
Atypical_PIKK_ATM_ATM_ST	Q9UBU7	DBF4	Q13315	ATM	S613	E607K	607	Missense	distal	-6	no	10.194	9.893	EPSD	ICGC;COSMIC	9.540	Down-regulation
Atypical_PIKK_ATM_ATM_ST	Q9UBU7	DBF4	Q13315	ATM	S665	L658P	658	Missense	distal	-7	no	9.848	10.199	EPSD	ICGC;COSMIC	9.540	Up-regulation
Atypical_PIKK_ATM_ATM_ST	P41236	PPP1R2	Q13315	ATM	S44	S44F	44	Missense	central	0	yes	13.291	0.000	PhosphoSitePlus	ICGC;CCLE	9.540	Loss
Atypical_PIKK_ATM_ATM_ST	Q14247	CTTN	Q13315	ATM	T24	D25Y	25	Missense	proximal	1	no	9.336	9.651	EPSD	ICGC	9.540	Gain
Atypical_PIKK_ATM_ATM_ST	Q14247	CTTN	Q13315	ATM	S47	K42N	42	Missense	distal	-5	no	9.736	9.792	EPSD	ICGC;COSMIC	9.540	Up-regulation
Atypical_PIKK_ATM_ATM_ST	Q14247	CTTN	Q13315	ATM	S47	T43M	43	Missense	distal	-4	no	9.736	9.112	EPSD	ICGC;COSMIC	9.540	Loss
Atypical_PIKK_ATM_ATM_ST	Q14247	CTTN	Q13315	ATM	S47	G46V	46	Missense	proximal	-1	no	9.736	9.504	EPSD	ICGC;COSMIC	9.540	Loss
Atypical_PIKK_ATM_ATM_ST	Q14247	CTTN	Q13315	ATM	S47	G48R	48	Missense	proximal	1	no	9.736	9.558	EPSD	ICGC;COSMIC	9.540	Down-regulation
Atypical_PIKK_ATM_ATM_ST	Q14247	CTTN	Q13315	ATM	S113	V115L	115	Missense	proximal	2	no	14.639	14.287	PhosphoSitePlus	ICGC	9.540	Down-regulation
Atypical_PIKK_ATM_ATM_ST	Q14247	CTTN	Q13315	ATM	S113	G120C	120	Missense	distal	7	no	14.639	14.650	PhosphoSitePlus	ICGC	9.540	Up-regulation
Atypical_PIKK_ATM_ATM_ST	Q14247	CTTN	Q13315	ATM	S113	Q114H	114	Missense	proximal	1	no	14.639	-0.270	PhosphoSitePlus	ICGC	9.540	Loss
Atypical_PIKK_ATM_ATM_ST	Q14247	CTTN	Q13315	ATM	S150	K144N	144	Missense	distal	-6	no	13.584	13.582	EPSD	ICGC	9.540	Down-regulation
Atypical_PIKK_ATM_ATM_ST	Q14247	CTTN	Q13315	ATM	S187	G180V	180	Missense	distal	-7	no	13.838	13.871	EPSD	ICGC;COSMIC	9.540	Up-regulation
Atypical_PIKK_ATM_ATM_ST	Q14247	CTTN	Q13315	ATM	S187	S187P	187	Missense	central	0	yes	13.838	0.000	EPSD	ICGC	9.540	Loss
Atypical_PIKK_ATM_ATM_ST	Q14247	CTTN	Q13315	ATM	S224	G231R	231	Missense	distal	7	no	14.223	14.217	EPSD	ICGC	9.540	Down-regulation
Atypical_PIKK_ATM_ATM_ST	Q14247	CTTN	Q13315	ATM	S298	G305V	305	Missense	distal	7	no	15.343	15.350	EPSD	ICGC	9.540	Up-regulation
Atypical_PIKK_ATM_ATM_ST	Q14247	CTTN	Q13315	ATM	T399	T401M	401	Missense	proximal	2	no	14.506	13.711	EPSD	ICGC;COSMIC	9.540	Down-regulation
Atypical_PIKK_ATM_ATM_ST	Q14247	CTTN	Q13315	ATM	T399	T401A	401	Missense	proximal	2	no	14.506	14.185	EPSD	ICGC	9.540	Down-regulation
Atypical_PIKK_ATM_ATM_ST	Q14247	CTTN	Q13315	ATM	T399	S405L	405	Missense	distal	6	no	14.506	14.450	EPSD	ICGC;COSMIC;GDSC	9.540	Down-regulation
Atypical_PIKK_ATM_ATM_ST	Q14247	CTTN	Q13315	ATM	T401	T401M	401	Missense	central	0	yes	9.952	0.000	EPSD	ICGC;COSMIC	9.540	Loss
Atypical_PIKK_ATM_ATM_ST	Q14247	CTTN	Q13315	ATM	T401	T401A	401	Missense	central	0	yes	9.952	0.000	EPSD	ICGC	9.540	Loss
Atypical_PIKK_ATM_ATM_ST	Q14247	CTTN	Q13315	ATM	T401	S405L	405	Missense	distal	4	no	9.952	10.293	EPSD	ICGC;COSMIC;GDSC	9.540	Up-regulation
Atypical_PIKK_ATM_ATM_ST	Q14247	CTTN	Q13315	ATM	T401	A407T	407	Missense	distal	6	no	9.952	9.935	EPSD	ICGC;COSMIC	9.540	Down-regulation
Atypical_PIKK_ATM_ATM_ST	Q14247	CTTN	Q13315	ATM	S405	A407T	407	Missense	proximal	2	no	9.234	9.555	EPSD	ICGC;COSMIC	9.540	Gain
Atypical_PIKK_ATM_ATM_ST	Q9Y6D9	MAD1L1	Q13315	ATM	S185	Q188L	188	Missense	distal	3	no	9.557	9.757	EPSD	ICGC;COSMIC	9.540	Up-regulation
Atypical_PIKK_ATM_ATM_ST	Q9Y6D9	MAD1L1	Q13315	ATM	S428	E426Q	426	Missense	proximal	-2	no	10.144	9.839	EPSD	ICGC;COSMIC	9.540	Down-regulation
Atypical_PIKK_ATM_ATM_ST	Q9Y6D9	MAD1L1	Q13315	ATM	S562	R558Q	558	Missense	distal	-4	no	14.822	15.187	EPSD	ICGC;COSMIC	9.540	Up-regulation
Atypical_PIKK_ATM_ATM_ST	P15374	UCHL3	Q13315	ATM	S75	K72T	72	Missense	distal	-3	no	16.287	16.312	PhosphoSitePlus	ICGC	9.540	Up-regulation
Atypical_PIKK_ATM_ATM_ST	P15374	UCHL3	Q13315	ATM	S75	I73T	73	Missense	proximal	-2	no	16.287	16.889	PhosphoSitePlus	ICGC;COSMIC	9.540	Up-regulation
Atypical_PIKK_ATM_ATM_ST	P15374	UCHL3	Q13315	ATM	S130	R134L	134	Missense	distal	4	no	10.957	11.116	EPSD	ICGC	9.540	Up-regulation
Atypical_PIKK_ATM_ATM_ST	P15374	UCHL3	Q13315	ATM	S130	S126F	126	Missense	distal	-4	no	10.957	9.558	EPSD	ICGC	9.540	Down-regulation
Atypical_PIKK_ATM_ATM_ST	Q70CQ2	USP34	Q13315	ATM	S143	E138G	138	Missense	distal	-5	no	9.892	10.112	EPSD	ICGC	9.540	Up-regulation
Atypical_PIKK_ATM_ATM_ST	Q70CQ2	USP34	Q13315	ATM	S143	S150N	150	Missense	distal	7	no	9.892	9.907	EPSD	ICGC;COSMIC;GDSC;CCLE	9.540	Up-regulation
Atypical_PIKK_ATM_ATM_ST	Q70CQ2	USP34	Q13315	ATM	T188	D185V	185	Missense	distal	-3	no	13.341	13.513	EPSD	ICGC;COSMIC	9.540	Up-regulation
Atypical_PIKK_ATM_ATM_ST	Q70CQ2	USP34	Q13315	ATM	T188	P181H	181	Missense	distal	-7	no	13.341	13.264	EPSD	ICGC;COSMIC	9.540	Down-regulation
Atypical_PIKK_ATM_ATM_ST	Q70CQ2	USP34	Q13315	ATM	S649	G652S	652	Missense	distal	3	no	14.044	13.913	EPSD	ICGC;COSMIC	9.540	Down-regulation
Atypical_PIKK_ATM_ATM_ST	Q70CQ2	USP34	Q13315	ATM	S658	M661T	661	Missense	distal	3	no	12.913	12.737	EPSD	ICGC	9.540	Down-regulation
Atypical_PIKK_ATM_ATM_ST	Q70CQ2	USP34	Q13315	ATM	S658	G652S	652	Missense	distal	-6	no	12.913	13.115	EPSD	ICGC;COSMIC	9.540	Up-regulation
Atypical_PIKK_ATM_ATM_ST	Q70CQ2	USP34	Q13315	ATM	S718	A715E	715	Missense	distal	-3	no	15.869	16.155	EPSD;PhosphoSitePlus	ICGC	9.540	Up-regulation
Atypical_PIKK_ATM_ATM_ST	Q70CQ2	USP34	Q13315	ATM	S832	G834V	834	Missense	proximal	2	no	12.174	12.141	EPSD	ICGC	9.540	Down-regulation
Atypical_PIKK_ATM_ATM_ST	Q70CQ2	USP34	Q13315	ATM	S920	L927P	927	Missense	distal	7	no	11.689	11.688	EPSD	ICGC;COSMIC	9.540	Down-regulation
Atypical_PIKK_ATM_ATM_ST	Q70CQ2	USP34	Q13315	ATM	S920	L923R	923	Missense	distal	3	no	11.689	11.592	EPSD	ICGC;COSMIC	9.540	Down-regulation
Atypical_PIKK_ATM_ATM_ST	Q70CQ2	USP34	Q13315	ATM	S920	N913K	913	Missense	distal	-7	no	11.689	11.563	EPSD	ICGC	9.540	Down-regulation
Atypical_PIKK_ATM_ATM_ST	Q70CQ2	USP34	Q13315	ATM	S1152	I1148M	1148	Missense	distal	-4	no	10.297	10.001	EPSD	ICGC;COSMIC	9.540	Down-regulation
Atypical_PIKK_ATM_ATM_ST	Q70CQ2	USP34	Q13315	ATM	S1375	D1373N	1373	Missense	proximal	-2	no	10.765	10.884	EPSD	ICGC;COSMIC	9.540	Up-regulation
Atypical_PIKK_ATM_ATM_ST	Q70CQ2	USP34	Q13315	ATM	S1751	D1749E	1749	Missense	proximal	-2	no	15.444	15.923	PhosphoSitePlus;EPSD	ICGC	9.540	Up-regulation
Atypical_PIKK_ATM_ATM_ST	Q70CQ2	USP34	Q13315	ATM	S1994	E1996K	1996	Missense	proximal	2	no	11.193	9.862	EPSD	ICGC;COSMIC	9.540	Down-regulation
Atypical_PIKK_ATM_ATM_ST	Q70CQ2	USP34	Q13315	ATM	S1994	V2001I	2001	Missense	distal	7	no	11.193	11.176	EPSD	ICGC	9.540	Down-regulation
Atypical_PIKK_ATM_ATM_ST	Q70CQ2	USP34	Q13315	ATM	S2127	R2129S	2129	Missense	proximal	2	no	8.599	9.597	EPSD	ICGC;COSMIC	9.540	Gain
Atypical_PIKK_ATM_ATM_ST	Q70CQ2	USP34	Q13315	ATM	S3127	P3121S	3121	Missense	distal	-6	no	9.522	9.581	EPSD	ICGC	9.540	Gain
Atypical_PIKK_ATM_ATM_ST	Q70CQ2	USP34	Q13315	ATM	T3195	Q3196H	3196	Missense	proximal	1	no	13.155	-1.754	EPSD	ICGC;COSMIC	9.540	Loss
Atypical_PIKK_ATM_ATM_ST	Q70CQ2	USP34	Q13315	ATM	T3350	T3343I	3343	Missense	distal	-7	no	10.611	10.028	EPSD	ICGC;COSMIC	9.540	Down-regulation
Atypical_PIKK_ATM_ATM_ST	Q70CQ2	USP34	Q13315	ATM	T3350	R3356H	3356	Missense	distal	6	no	10.611	10.595	EPSD	ICGC;COSMIC	9.540	Down-regulation
Atypical_PIKK_ATM_ATM_ST	Q70CQ2	USP34	Q13315	ATM	S3493	P3496T	3496	Missense	distal	3	no	15.953	15.882	EPSD	ICGC;COSMIC	9.540	Down-regulation
Atypical_PIKK_ATM_ATM_ST	Q70CQ2	USP34	Q13315	ATM	S3493	E3497K	3497	Missense	distal	4	no	15.953	16.331	EPSD	ICGC;COSMIC	9.540	Up-regulation
Atypical_PIKK_ATM_ATM_ST	Q70CQ2	USP34	Q13315	ATM	S3503	C3504Y	3504	Missense	proximal	1	no	3.497	9.992	EPSD	ICGC;COSMIC	9.540	Gain
Atypical_PIKK_ATM_ATM_ST	Q13769	THOC5	Q13315	ATM	S28	D29E	29	Missense	proximal	1	no	9.532	9.666	EPSD	ICGC	9.540	Gain
Atypical_PIKK_ATM_ATM_ST	Q13769	THOC5	Q13315	ATM	S28	R27Q	27	Missense	proximal	-1	no	9.532	9.839	EPSD	ICGC;COSMIC	9.540	Gain
Atypical_PIKK_ATM_ATM_ST	Q13769	THOC5	Q13315	ATM	S307	F301L	301	Missense	distal	-6	no	13.722	13.965	EPSD;PhosphoSitePlus	ICGC	9.540	Up-regulation
Atypical_PIKK_ATM_ATM_ST	Q13769	THOC5	Q13315	ATM	T536	A542E	542	Missense	distal	6	no	10.670	10.688	EPSD	ICGC;COSMIC	9.540	Up-regulation
Atypical_PIKK_ATM_ATM_ST	Q9UQE7	SMC3	Q13315	ATM	S177	S177F	177	Missense	central	0	yes	10.314	0.000	EPSD	ICGC	9.540	Loss
Atypical_PIKK_ATM_ATM_ST	Q9UQE7	SMC3	Q13315	ATM	T347	E343V	343	Missense	distal	-4	no	9.679	8.411	EPSD	ICGC;COSMIC	9.540	Loss
Atypical_PIKK_ATM_ATM_ST	Q9UQE7	SMC3	Q13315	ATM	S383	R381Q	381	Missense	proximal	-2	no	12.017	12.336	EPSD	ICGC;COSMIC	9.540	Up-regulation
Atypical_PIKK_ATM_ATM_ST	Q9UQE7	SMC3	Q13315	ATM	T640	T640A	640	Missense	central	0	yes	10.150	0.000	EPSD	ICGC;COSMIC	9.540	Loss
Atypical_PIKK_ATM_ATM_ST	Q9UQE7	SMC3	Q13315	ATM	T640	M636I	636	Missense	distal	-4	no	10.150	10.446	EPSD	ICGC	9.540	Up-regulation
Atypical_PIKK_ATM_ATM_ST	Q9UQE7	SMC3	Q13315	ATM	T640	A643S	643	Missense	distal	3	no	10.150	10.094	EPSD	ICGC;COSMIC	9.540	Down-regulation
Atypical_PIKK_ATM_ATM_ST	Q9UQE7	SMC3	Q13315	ATM	S1083	S1089L	1089	Missense	distal	6	no	16.913	16.857	PhosphoSitePlus	ICGC;COSMIC	9.540	Down-regulation
Atypical_PIKK_ATM_ATM_ST	Q13315	ATM	Q13315	ATM	T86	V82L	82	Missense	distal	-4	no	13.802	13.852	EPSD	ICGC	9.540	Up-regulation
Atypical_PIKK_ATM_ATM_ST	Q13315	ATM	Q13315	ATM	T86	Q91H	91	Missense	distal	5	no	13.802	13.888	EPSD	ICGC;COSMIC	9.540	Up-regulation
Atypical_PIKK_ATM_ATM_ST	Q13315	ATM	Q13315	ATM	S200	G204V	204	Missense	distal	4	no	14.132	14.309	EPSD	ICGC;COSMIC	9.540	Up-regulation
Atypical_PIKK_ATM_ATM_ST	Q13315	ATM	Q13315	ATM	T297	Q298K	298	Missense	proximal	1	no	14.760	7.912	EPSD	ICGC;COSMIC	9.540	Loss
Atypical_PIKK_ATM_ATM_ST	Q13315	ATM	Q13315	ATM	S363	S367F	367	Missense	distal	4	no	9.182	10.010	EPSD	ICGC;COSMIC	9.540	Gain
Atypical_PIKK_ATM_ATM_ST	Q13315	ATM	Q13315	ATM	S367	L364F	364	Missense	distal	-3	no	15.079	15.942	PhosphoSitePlus;EPSD	ICGC;COSMIC	9.540	Up-regulation
Atypical_PIKK_ATM_ATM_ST	Q13315	ATM	Q13315	ATM	S367	D360Y	360	Missense	distal	-7	no	15.079	15.007	PhosphoSitePlus;EPSD	ICGC;COSMIC	9.540	Down-regulation
Atypical_PIKK_ATM_ATM_ST	Q13315	ATM	Q13315	ATM	S367	S367F	367	Missense	central	0	yes	15.079	0.000	PhosphoSitePlus;EPSD	ICGC;COSMIC	9.540	Loss
Atypical_PIKK_ATM_ATM_ST	Q13315	ATM	Q13315	ATM	S369	L364F	364	Missense	distal	-5	no	10.128	10.429	EPSD	ICGC;COSMIC	9.540	Up-regulation
Atypical_PIKK_ATM_ATM_ST	Q13315	ATM	Q13315	ATM	S369	S367F	367	Missense	proximal	-2	no	10.128	9.228	EPSD	ICGC;COSMIC	9.540	Loss
Atypical_PIKK_ATM_ATM_ST	Q13315	ATM	Q13315	ATM	T373	S378R	378	Missense	distal	5	no	13.680	13.845	EPSD	ICGC;COSMIC	9.540	Up-regulation
Atypical_PIKK_ATM_ATM_ST	Q13315	ATM	Q13315	ATM	T373	S367F	367	Missense	distal	-6	no	13.680	13.148	EPSD	ICGC;COSMIC	9.540	Down-regulation
Atypical_PIKK_ATM_ATM_ST	Q13315	ATM	Q13315	ATM	S440	Q441H	441	Missense	proximal	1	no	13.724	-1.185	EPSD;PhosphoSitePlus	ICGC	9.540	Loss
Atypical_PIKK_ATM_ATM_ST	Q13315	ATM	Q13315	ATM	S646	V648L	648	Missense	proximal	2	no	10.013	9.661	EPSD	ICGC	9.540	Down-regulation
Atypical_PIKK_ATM_ATM_ST	Q13315	ATM	Q13315	ATM	S1137	G1130V	1130	Missense	distal	-7	no	9.607	9.639	EPSD	ICGC;COSMIC	9.540	Up-regulation
Atypical_PIKK_ATM_ATM_ST	Q13315	ATM	Q13315	ATM	S1878	Q1879K	1879	Missense	proximal	1	no	14.356	7.508	EPSD	ICGC;COSMIC	9.540	Loss
Atypical_PIKK_ATM_ATM_ST	Q13315	ATM	Q13315	ATM	T1885	E1892D	1892	Missense	distal	7	no	12.155	12.168	EPSD;PhosphoSitePlus	ICGC	9.540	Up-regulation
Atypical_PIKK_ATM_ATM_ST	Q13315	ATM	Q13315	ATM	T1885	Q1879K	1879	Missense	distal	-6	no	12.155	12.079	EPSD;PhosphoSitePlus	ICGC;COSMIC	9.540	Down-regulation
Atypical_PIKK_ATM_ATM_ST	Q13315	ATM	Q13315	ATM	S1893	E1892D	1892	Missense	proximal	-1	no	11.705	11.440	EPSD;PhosphoSitePlus	ICGC	9.540	Down-regulation
Atypical_PIKK_ATM_ATM_ST	Q13315	ATM	Q13315	ATM	S1893	R1898L	1898	Missense	distal	5	no	11.705	11.704	EPSD;PhosphoSitePlus	ICGC	9.540	Down-regulation
Atypical_PIKK_ATM_ATM_ST	Q13315	ATM	Q13315	ATM	S1981	S1988I	1988	Missense	distal	7	no	14.545	14.577	EPSD;PhosphoSitePlus	ICGC;COSMIC	9.540	Up-regulation
Atypical_PIKK_ATM_ATM_ST	Q13315	ATM	Q13315	ATM	S1981	E1979V	1979	Missense	proximal	-2	no	14.545	13.700	EPSD;PhosphoSitePlus	ICGC	9.540	Down-regulation
Atypical_PIKK_ATM_ATM_ST	Q13315	ATM	Q13315	ATM	S2000	S2000I	2000	Missense	central	0	yes	9.944	0.000	EPSD	ICGC	9.540	Loss
Atypical_PIKK_ATM_ATM_ST	Q13315	ATM	Q13315	ATM	S2242	E2245Q	2245	Missense	distal	3	no	14.683	14.942	EPSD	ICGC;COSMIC	9.540	Up-regulation
Atypical_PIKK_ATM_ATM_ST	Q13315	ATM	Q13315	ATM	S2592	D2597N	2597	Missense	distal	5	no	13.755	13.643	EPSD	ICGC;COSMIC	9.540	Down-regulation
Atypical_PIKK_ATM_ATM_ST	Q13315	ATM	Q13315	ATM	S2996	S3001R	3001	Missense	distal	5	no	11.474	11.639	EPSD;PhosphoSitePlus	ICGC;COSMIC	9.540	Up-regulation
Atypical_PIKK_ATM_ATM_ST	Q13315	ATM	Q13315	ATM	S2996	N3003K	3003	Missense	distal	7	no	11.474	11.482	EPSD;PhosphoSitePlus	ICGC	9.540	Up-regulation
Atypical_PIKK_ATM_ATM_ST	Q13315	ATM	Q13315	ATM	S2996	N3003D	3003	Missense	distal	7	no	11.474	11.467	EPSD;PhosphoSitePlus	ICGC;COSMIC	9.540	Down-regulation
Atypical_PIKK_ATM_ATM_ST	Q8N680	ZBTB2	Q13315	ATM	S115	I108F	108	Missense	distal	-7	no	13.086	12.921	PhosphoSitePlus	ICGC;COSMIC	9.540	Down-regulation
Atypical_PIKK_ATM_ATM_ST	Q8N680	ZBTB2	Q13315	ATM	S115	S112R	112	Missense	distal	-3	no	13.086	13.826	PhosphoSitePlus	ICGC	9.540	Up-regulation
Atypical_PIKK_ATM_ATM_ST	Q8N680	ZBTB2	Q13315	ATM	S115	Q116H	116	Missense	proximal	1	no	13.086	-1.823	PhosphoSitePlus	ICGC;COSMIC	9.540	Loss
Atypical_PIKK_ATM_ATM_ST	Q8N680	ZBTB2	Q13315	ATM	S167	T163N	163	Missense	distal	-4	no	14.026	13.481	EPSD	ICGC	9.540	Down-regulation
Atypical_PIKK_ATM_ATM_ST	Q8N680	ZBTB2	Q13315	ATM	S167	S167R	167	Missense	central	0	yes	14.026	0.000	EPSD	ICGC	9.540	Loss
Atypical_PIKK_ATM_ATM_ST	Q8N680	ZBTB2	Q13315	ATM	S284	R290H	290	Missense	distal	6	no	15.839	15.823	EPSD	ICGC;COSMIC	9.540	Down-regulation
Atypical_PIKK_ATM_ATM_ST	Q8N680	ZBTB2	Q13315	ATM	S284	Q286H	286	Missense	proximal	2	no	15.839	15.460	EPSD	ICGC;COSMIC	9.540	Down-regulation
Atypical_PIKK_ATM_ATM_ST	Q8N680	ZBTB2	Q13315	ATM	S435	G434V	434	Missense	proximal	-1	no	13.573	13.341	EPSD	ICGC;COSMIC	9.540	Down-regulation
Atypical_PIKK_ATM_ATM_ST	Q7L7X3	TAOK1	Q13315	ATM	S177	G171C	171	Missense	distal	-6	no	10.261	10.083	EPSD	ICGC;COSMIC	9.540	Down-regulation
Atypical_PIKK_ATM_ATM_ST	Q7L7X3	TAOK1	Q13315	ATM	S421	R415T	415	Missense	distal	-6	no	11.232	11.343	EPSD	ICGC;COSMIC	9.540	Up-regulation
Atypical_PIKK_ATM_ATM_ST	Q7L7X3	TAOK1	Q13315	ATM	T502	R495S	495	Missense	distal	-7	no	11.045	11.443	EPSD	ICGC;COSMIC	9.540	Up-regulation
Atypical_PIKK_ATM_ATM_ST	Q7L7X3	TAOK1	Q13315	ATM	T502	Q503K	503	Missense	proximal	1	no	11.045	4.196	EPSD	ICGC;COSMIC	9.540	Loss
Atypical_PIKK_ATM_ATM_ST	Q7L7X3	TAOK1	Q13315	ATM	T576	K578Q	578	Missense	proximal	2	no	9.562	10.080	EPSD	ICGC	9.540	Up-regulation
Atypical_PIKK_ATM_ATM_ST	Q7L7X3	TAOK1	Q13315	ATM	T576	Q574H	574	Missense	proximal	-2	no	9.562	9.259	EPSD	ICGC;COSMIC	9.540	Loss
Atypical_PIKK_ATM_ATM_ST	Q7L7X3	TAOK1	Q13315	ATM	T643	K645N	645	Missense	proximal	2	no	12.581	12.760	PhosphoSitePlus;EPSD	ICGC;COSMIC	9.540	Up-regulation
Atypical_PIKK_ATM_ATM_ST	P04637	TP53	Q13315	ATM	S15	E11K	11	Missense	distal	-4	no	17.866	16.895	EPSD;PhosphoSitePlus	ICGC;COSMIC	9.540	Down-regulation
Atypical_PIKK_ATM_ATM_ST	P04637	TP53	Q13315	ATM	S37	P34L	34	Missense	distal	-3	no	15.394	15.407	EPSD	ICGC;COSMIC	9.540	Up-regulation
Atypical_PIKK_ATM_ATM_ST	P04637	TP53	Q13315	ATM	S37	S33F	33	Missense	distal	-4	no	15.394	13.995	EPSD	ICGC;COSMIC	9.540	Down-regulation
Atypical_PIKK_ATM_ATM_ST	P04637	TP53	Q13315	ATM	S37	N30I	30	Missense	distal	-7	no	15.394	14.916	EPSD	ICGC	9.540	Down-regulation
Atypical_PIKK_ATM_ATM_ST	P04637	TP53	Q13315	ATM	S46	D48G	48	Missense	proximal	2	no	12.775	11.536	PhosphoSitePlus;EPSD	ICGC;COSMIC	9.540	Down-regulation
Atypical_PIKK_ATM_ATM_ST	P04637	TP53	Q13315	ATM	S46	Q52K	52	Missense	distal	6	no	12.775	12.776	PhosphoSitePlus;EPSD	ICGC	9.540	Up-regulation
Atypical_PIKK_ATM_ATM_ST	P04637	TP53	Q13315	ATM	S99	Q100K	100	Missense	proximal	1	no	12.537	5.688	EPSD	ICGC;COSMIC	9.540	Loss
Atypical_PIKK_ATM_ATM_ST	P04637	TP53	Q13315	ATM	S99	P92T	92	Missense	distal	-7	no	12.537	12.692	EPSD	ICGC;COSMIC	9.540	Up-regulation
Atypical_PIKK_ATM_ATM_ST	P04637	TP53	Q13315	ATM	S99	P92H	92	Missense	distal	-7	no	12.537	12.459	EPSD	ICGC;COSMIC	9.540	Down-regulation
Atypical_PIKK_ATM_ATM_ST	P04637	TP53	Q13315	ATM	S99	G105A	105	Missense	distal	6	no	12.537	12.562	EPSD	ICGC;COSMIC	9.540	Up-regulation
Atypical_PIKK_ATM_ATM_ST	P04637	TP53	Q13315	ATM	S106	Q100K	100	Missense	distal	-6	no	10.952	10.876	EPSD	ICGC;COSMIC	9.540	Down-regulation
Atypical_PIKK_ATM_ATM_ST	P04637	TP53	Q13315	ATM	S106	F113I	113	Missense	distal	7	no	10.952	10.924	EPSD	ICGC;COSMIC	9.540	Down-regulation
Atypical_PIKK_ATM_ATM_ST	P04637	TP53	Q13315	ATM	S106	G105A	105	Missense	proximal	-1	no	10.952	10.983	EPSD	ICGC;COSMIC	9.540	Up-regulation
Atypical_PIKK_ATM_ATM_ST	P04637	TP53	Q13315	ATM	S127	T125R	125	Missense	proximal	-2	no	9.567	9.212	EPSD	ICGC;COSMIC	9.540	Loss
Atypical_PIKK_ATM_ATM_ST	P04637	TP53	Q13315	ATM	S127	F134C	134	Missense	distal	7	no	9.567	9.559	EPSD	ICGC;COSMIC;CCLE	9.540	Down-regulation
Atypical_PIKK_ATM_ATM_ST	P04637	TP53	Q13315	ATM	S127	C124G	124	Missense	distal	-3	no	9.567	9.678	EPSD	ICGC;COSMIC	9.540	Up-regulation
Atypical_PIKK_ATM_ATM_ST	P04637	TP53	Q13315	ATM	S127	C124R	124	Missense	distal	-3	no	9.567	10.139	EPSD	ICGC;COSMIC;GDSC;CCLE	9.540	Up-regulation
Atypical_PIKK_ATM_ATM_ST	P04637	TP53	Q13315	ATM	S127	L130H	130	Missense	distal	3	no	9.567	9.508	EPSD	ICGC;COSMIC	9.540	Loss
Atypical_PIKK_ATM_ATM_ST	P04637	TP53	Q13315	ATM	S127	T125A	125	Missense	proximal	-2	no	9.567	9.467	EPSD	ICGC;COSMIC	9.540	Loss
Atypical_PIKK_ATM_ATM_ST	P04637	TP53	Q13315	ATM	S127	K120N	120	Missense	distal	-7	no	9.567	9.693	EPSD	ICGC;COSMIC;GDSC;CCLE	9.540	Up-regulation
Atypical_PIKK_ATM_ATM_ST	P04637	TP53	Q13315	ATM	S127	N131Y	131	Missense	distal	4	no	9.567	9.743	EPSD	ICGC;COSMIC	9.540	Up-regulation
Atypical_PIKK_ATM_ATM_ST	P04637	TP53	Q13315	ATM	S127	K120M	120	Missense	distal	-7	no	9.567	9.404	EPSD	ICGC;COSMIC	9.540	Loss
Atypical_PIKK_ATM_ATM_ST	P04637	TP53	Q13315	ATM	S127	K132M	132	Missense	distal	5	no	9.567	9.748	EPSD	ICGC;COSMIC;CCLE	9.540	Up-regulation
Atypical_PIKK_ATM_ATM_ST	P04637	TP53	Q13315	ATM	S127	M133T	133	Missense	distal	6	no	9.567	9.586	EPSD	ICGC;COSMIC	9.540	Up-regulation
Atypical_PIKK_ATM_ATM_ST	P04637	TP53	Q13315	ATM	S127	K120R	120	Missense	distal	-7	no	9.567	9.481	EPSD	ICGC;COSMIC	9.540	Loss
Atypical_PIKK_ATM_ATM_ST	P04637	TP53	Q13315	ATM	S127	C124Y	124	Missense	distal	-3	no	9.567	9.532	EPSD	ICGC;COSMIC	9.540	Loss
Atypical_PIKK_ATM_ATM_ST	P04637	TP53	Q13315	ATM	S392	F385L	385	Missense	distal	-7	no	9.915	10.157	EPSD	ICGC;COSMIC	9.540	Up-regulation
Atypical_PIKK_ATM_ATM_ST	Q9H3D4	TP63	Q13315	ATM	S160	P161Q	161	Missense	proximal	1	no	8.883	13.685	EPSD	ICGC;COSMIC	9.540	Gain
Atypical_PIKK_ATM_ATM_ST	Q9H3D4	TP63	Q13315	ATM	S162	P166S	166	Missense	distal	4	no	9.666	9.544	EPSD	ICGC;COSMIC	9.540	Down-regulation
Atypical_PIKK_ATM_ATM_ST	Q9H3D4	TP63	Q13315	ATM	S162	P161A	161	Missense	proximal	-1	no	9.666	9.798	EPSD	ICGC	9.540	Up-regulation
Atypical_PIKK_ATM_ATM_ST	Q9H3D4	TP63	Q13315	ATM	S162	P161Q	161	Missense	proximal	-1	no	9.666	9.892	EPSD	ICGC;COSMIC	9.540	Up-regulation
Atypical_PIKK_ATM_ATM_ST	Q9H3D4	TP63	Q13315	ATM	S162	S162L	162	Missense	central	0	yes	9.666	0.000	EPSD	ICGC;COSMIC;GDSC;CCLE	9.540	Loss
Atypical_PIKK_ATM_ATM_ST	Q9H3D4	TP63	Q13315	ATM	S162	I165T	165	Missense	distal	3	no	9.666	9.245	EPSD	ICGC;COSMIC	9.540	Loss
Atypical_PIKK_ATM_ATM_ST	Q9H3D4	TP63	Q13315	ATM	S162	D157N	157	Missense	distal	-5	no	9.666	9.849	EPSD	ICGC;COSMIC	9.540	Up-regulation
Atypical_PIKK_ATM_ATM_ST	P27707	DCK	Q13315	ATM	T64	R57I	57	Missense	distal	-7	no	13.775	13.510	EPSD	ICGC	9.540	Down-regulation
Atypical_PIKK_ATM_ATM_ST	P27707	DCK	Q13315	ATM	T64	C59F	59	Missense	distal	-5	no	13.775	14.006	EPSD	ICGC	9.540	Up-regulation
Atypical_PIKK_ATM_ATM_ST	P27707	DCK	Q13315	ATM	T64	S63T	63	Missense	proximal	-1	no	13.775	13.786	EPSD	ICGC;COSMIC	9.540	Up-regulation
Atypical_PIKK_ATM_ATM_ST	P27707	DCK	Q13315	ATM	S74	T72A	72	Missense	proximal	-2	no	16.242	16.143	PhosphoSitePlus	ICGC;COSMIC	9.540	Down-regulation
Atypical_PIKK_ATM_ATM_ST	P27707	DCK	Q13315	ATM	S74	T72K	72	Missense	proximal	-2	no	16.242	15.935	PhosphoSitePlus	ICGC;COSMIC	9.540	Down-regulation
Atypical_PIKK_ATM_ATM_ST	O15111	CHUK	Q13315	ATM	S473	Q474K	474	Missense	proximal	1	no	13.086	6.238	PhosphoSitePlus	ICGC;COSMIC	9.540	Loss
Atypical_PIKK_ATM_ATM_ST	Q9BUR4	WRAP53	Q13315	ATM	T6	E5D	5	Missense	proximal	-1	no	10.869	10.605	EPSD	ICGC;COSMIC	9.540	Down-regulation
Atypical_PIKK_ATM_ATM_ST	Q9BUR4	WRAP53	Q13315	ATM	S54	L53F	53	Missense	proximal	-1	no	10.205	9.914	EPSD	ICGC;COSMIC	9.540	Down-regulation
Atypical_PIKK_ATM_ATM_ST	Q9BUR4	WRAP53	Q13315	ATM	S54	D56Y	56	Missense	proximal	2	no	10.205	8.964	EPSD	ICGC;COSMIC	9.540	Loss
Atypical_PIKK_ATM_ATM_ST	Q9BUR4	WRAP53	Q13315	ATM	S54	R47M	47	Missense	distal	-7	no	10.205	10.129	EPSD	ICGC	9.540	Down-regulation
Atypical_PIKK_ATM_ATM_ST	Q9BUR4	WRAP53	Q13315	ATM	S64	R68G	68	Missense	distal	4	no	15.675	15.623	PhosphoSitePlus	ICGC;COSMIC	9.540	Down-regulation
Atypical_PIKK_ATM_ATM_ST	Q9BUR4	WRAP53	Q13315	ATM	S64	D71N	71	Missense	distal	7	no	15.675	15.682	PhosphoSitePlus	ICGC	9.540	Up-regulation
Atypical_PIKK_ATM_ATM_ST	Q8IX03	WWC1	Q13315	ATM	S141	Q142H	142	Missense	proximal	1	no	14.203	-0.706	EPSD	ICGC;COSMIC	9.540	Loss
Atypical_PIKK_ATM_ATM_ST	Q8IX03	WWC1	Q13315	ATM	S141	V146F	146	Missense	distal	5	no	14.203	14.297	EPSD	ICGC	9.540	Up-regulation
Atypical_PIKK_ATM_ATM_ST	Q8IX03	WWC1	Q13315	ATM	S141	V134F	134	Missense	distal	-7	no	14.203	13.854	EPSD	ICGC;COSMIC	9.540	Down-regulation
Atypical_PIKK_ATM_ATM_ST	Q8IX03	WWC1	Q13315	ATM	S141	W135L	135	Missense	distal	-6	no	14.203	14.264	EPSD	ICGC;COSMIC	9.540	Up-regulation
Atypical_PIKK_ATM_ATM_ST	Q8IX03	WWC1	Q13315	ATM	S438	L442I	442	Missense	distal	4	no	9.283	9.604	EPSD	ICGC;COSMIC	9.540	Gain
Atypical_PIKK_ATM_ATM_ST	Q8IX03	WWC1	Q13315	ATM	S535	P536Q	536	Missense	proximal	1	no	8.355	13.156	EPSD	ICGC;COSMIC	9.540	Gain
Atypical_PIKK_ATM_ATM_ST	Q8IX03	WWC1	Q13315	ATM	S539	P536Q	536	Missense	distal	-3	no	9.723	9.492	EPSD	ICGC;COSMIC	9.540	Loss
Atypical_PIKK_ATM_ATM_ST	Q8IX03	WWC1	Q13315	ATM	S539	S539P	539	Missense	central	0	yes	9.723	0.000	EPSD	ICGC;COSMIC	9.540	Loss
Atypical_PIKK_ATM_ATM_ST	Q8IX03	WWC1	Q13315	ATM	S539	S542T	542	Missense	distal	3	no	9.723	9.803	EPSD	ICGC;COSMIC	9.540	Up-regulation
Atypical_PIKK_ATM_ATM_ST	Q8IX03	WWC1	Q13315	ATM	S539	S535F	535	Missense	distal	-4	no	9.723	8.324	EPSD	ICGC	9.540	Loss
Atypical_PIKK_ATM_ATM_ST	Q8IX03	WWC1	Q13315	ATM	S539	S541F	541	Missense	proximal	2	no	9.723	8.245	EPSD	ICGC	9.540	Loss
Atypical_PIKK_ATM_ATM_ST	Q8IX03	WWC1	Q13315	ATM	S542	P536Q	536	Missense	distal	-6	no	10.585	10.607	EPSD	ICGC;COSMIC	9.540	Up-regulation
Atypical_PIKK_ATM_ATM_ST	Q8IX03	WWC1	Q13315	ATM	S542	S539P	539	Missense	distal	-3	no	10.585	10.781	EPSD	ICGC;COSMIC	9.540	Up-regulation
Atypical_PIKK_ATM_ATM_ST	Q8IX03	WWC1	Q13315	ATM	S542	S535F	535	Missense	distal	-7	no	10.585	9.756	EPSD	ICGC	9.540	Down-regulation
Atypical_PIKK_ATM_ATM_ST	Q8IX03	WWC1	Q13315	ATM	S542	S541F	541	Missense	proximal	-1	no	10.585	10.159	EPSD	ICGC	9.540	Down-regulation
Atypical_PIKK_ATM_ATM_ST	Q8IX03	WWC1	Q13315	ATM	S785	W780R	780	Missense	distal	-5	no	11.492	11.327	EPSD	ICGC;COSMIC	9.540	Down-regulation
Atypical_PIKK_ATM_ATM_ST	Q8IX03	WWC1	Q13315	ATM	S785	K791R	791	Missense	distal	6	no	11.492	11.496	EPSD	ICGC	9.540	Up-regulation
Atypical_PIKK_ATM_ATM_ST	Q8IX03	WWC1	Q13315	ATM	S785	L783I	783	Missense	proximal	-2	no	11.492	11.192	EPSD	ICGC;COSMIC	9.540	Down-regulation
Atypical_PIKK_ATM_ATM_ST	Q8IX03	WWC1	Q13315	ATM	S876	M879R	879	Missense	distal	3	no	12.923	12.852	EPSD	ICGC;COSMIC	9.540	Down-regulation
Atypical_PIKK_ATM_ATM_ST	Q8IX03	WWC1	Q13315	ATM	S914	R908W	908	Missense	distal	-6	no	15.951	15.783	EPSD	ICGC;COSMIC	9.540	Down-regulation
Atypical_PIKK_ATM_ATM_ST	Q8IX03	WWC1	Q13315	ATM	S914	V910L	910	Missense	distal	-4	no	15.951	16.001	EPSD	ICGC	9.540	Up-regulation
Atypical_PIKK_ATM_ATM_ST	Q8IX03	WWC1	Q13315	ATM	T1006	W1001L	1001	Missense	distal	-5	no	14.068	13.849	PhosphoSitePlus	ICGC	9.540	Down-regulation
Atypical_PIKK_ATM_ATM_ST	Q8IX03	WWC1	Q13315	ATM	T1006	E1008K	1008	Missense	proximal	2	no	14.068	12.737	PhosphoSitePlus	ICGC;COSMIC	9.540	Down-regulation
Atypical_PIKK_ATM_ATM_ST	P37275	ZEB1	Q13315	ATM	S309	P302L	302	Missense	distal	-7	no	11.175	10.823	EPSD	ICGC;COSMIC	9.540	Down-regulation
Atypical_PIKK_ATM_ATM_ST	P37275	ZEB1	Q13315	ATM	S309	P302S	302	Missense	distal	-7	no	11.175	11.411	EPSD	ICGC;COSMIC	9.540	Up-regulation
Atypical_PIKK_ATM_ATM_ST	P37275	ZEB1	Q13315	ATM	S313	P320H	320	Missense	distal	7	no	9.714	9.724	EPSD	ICGC;COSMIC	9.540	Up-regulation
Atypical_PIKK_ATM_ATM_ST	P37275	ZEB1	Q13315	ATM	S646	S645T	645	Missense	proximal	-1	no	9.613	9.623	EPSD	ICGC;COSMIC	9.540	Up-regulation
Atypical_PIKK_ATM_ATM_ST	P37275	ZEB1	Q13315	ATM	S646	S646F	646	Missense	central	0	yes	9.613	0.000	EPSD	ICGC;COSMIC	9.540	Loss
Atypical_PIKK_ATM_ATM_ST	P37275	ZEB1	Q13315	ATM	T702	S704F	704	Missense	proximal	2	no	10.969	9.491	EPSD	ICGC;COSMIC	9.540	Loss
Atypical_PIKK_ATM_ATM_ST	P37275	ZEB1	Q13315	ATM	S704	S704F	704	Missense	central	0	yes	10.144	0.000	EPSD	ICGC;COSMIC	9.540	Loss
Atypical_PIKK_ATM_ATM_ST	P37275	ZEB1	Q13315	ATM	S887	P892S	892	Missense	distal	5	no	12.085	11.904	EPSD	ICGC;COSMIC	9.540	Down-regulation
Atypical_PIKK_ATM_ATM_ST	P37275	ZEB1	Q13315	ATM	T890	P892S	892	Missense	proximal	2	no	9.705	10.159	EPSD	ICGC;COSMIC	9.540	Up-regulation
Atypical_PIKK_ATM_ATM_ST	P11166	SLC2A1	Q13315	ATM	S473	A472D	472	Missense	proximal	-1	no	14.050	14.156	EPSD	ICGC;COSMIC	9.540	Up-regulation
Atypical_PIKK_ATM_ATM_ST	P11166	SLC2A1	Q13315	ATM	S473	S473R	473	Missense	central	0	yes	14.050	0.000	EPSD	ICGC;COSMIC	9.540	Loss
Atypical_PIKK_ATM_ATM_ST	P11166	SLC2A1	Q13315	ATM	S473	G466D	466	Missense	distal	-7	no	14.050	14.340	EPSD	ICGC	9.540	Up-regulation
Atypical_PIKK_ATM_ATM_ST	P11166	SLC2A1	Q13315	ATM	T478	A472D	472	Missense	distal	-6	no	9.834	9.828	EPSD	ICGC;COSMIC	9.540	Down-regulation
Atypical_PIKK_ATM_ATM_ST	P11166	SLC2A1	Q13315	ATM	T478	S473R	473	Missense	distal	-5	no	9.834	9.910	EPSD	ICGC;COSMIC	9.540	Up-regulation
Atypical_PIKK_ATM_ATM_ST	P11166	SLC2A1	Q13315	ATM	S490	G487A	487	Missense	distal	-3	no	15.647	14.924	PhosphoSitePlus	ICGC;COSMIC	9.540	Down-regulation
Atypical_PIKK_ATM_ATM_ST	Q969R5	L3MBTL2	Q13315	ATM	S67	A61G	61	Missense	distal	-6	no	12.995	12.814	EPSD	ICGC;COSMIC	9.540	Down-regulation
Atypical_PIKK_ATM_ATM_ST	Q969R5	L3MBTL2	Q13315	ATM	S67	L72F	72	Missense	distal	5	no	12.995	13.137	EPSD	ICGC;COSMIC	9.540	Up-regulation
Atypical_PIKK_ATM_ATM_ST	Q969R5	L3MBTL2	Q13315	ATM	S73	L72F	72	Missense	proximal	-1	no	10.322	10.031	EPSD	ICGC;COSMIC	9.540	Down-regulation
Atypical_PIKK_ATM_ATM_ST	Q969R5	L3MBTL2	Q13315	ATM	S73	G75E	75	Missense	proximal	2	no	10.322	11.692	EPSD	ICGC;COSMIC	9.540	Up-regulation
Atypical_PIKK_ATM_ATM_ST	Q969R5	L3MBTL2	Q13315	ATM	S73	R78C	78	Missense	distal	5	no	10.322	10.383	EPSD	ICGC;COSMIC	9.540	Up-regulation
Atypical_PIKK_ATM_ATM_ST	Q969R5	L3MBTL2	Q13315	ATM	S79	G75E	75	Missense	distal	-4	no	9.437	10.504	EPSD	ICGC;COSMIC	9.540	Gain
Atypical_PIKK_ATM_ATM_ST	Q969R5	L3MBTL2	Q13315	ATM	S79	R78C	78	Missense	proximal	-1	no	9.437	9.612	EPSD	ICGC;COSMIC	9.540	Gain
Atypical_PIKK_ATM_ATM_ST	Q969R5	L3MBTL2	Q13315	ATM	S83	R78C	78	Missense	distal	-5	no	9.524	9.541	EPSD	ICGC;COSMIC	9.540	Gain
Atypical_PIKK_ATM_ATM_ST	Q969R5	L3MBTL2	Q13315	ATM	S85	R78C	78	Missense	distal	-7	no	9.703	9.428	EPSD	ICGC;COSMIC	9.540	Loss
Atypical_PIKK_ATM_ATM_ST	Q969R5	L3MBTL2	Q13315	ATM	T98	G94V	94	Missense	distal	-4	no	9.638	9.437	EPSD	ICGC	9.540	Loss
Atypical_PIKK_ATM_ATM_ST	Q969R5	L3MBTL2	Q13315	ATM	T98	G97C	97	Missense	proximal	-1	no	9.638	9.630	EPSD	ICGC	9.540	Down-regulation
Atypical_PIKK_ATM_ATM_ST	Q969R5	L3MBTL2	Q13315	ATM	S117	S115F	115	Missense	proximal	-2	no	9.893	8.993	EPSD	ICGC;COSMIC	9.540	Loss
Atypical_PIKK_ATM_ATM_ST	Q969R5	L3MBTL2	Q13315	ATM	S117	S115A	115	Missense	proximal	-2	no	9.893	9.705	EPSD	ICGC;COSMIC	9.540	Down-regulation
Atypical_PIKK_ATM_ATM_ST	Q969R5	L3MBTL2	Q13315	ATM	S221	E217K	217	Missense	distal	-4	no	11.280	10.308	EPSD	ICGC	9.540	Down-regulation
Atypical_PIKK_ATM_ATM_ST	Q969R5	L3MBTL2	Q13315	ATM	S335	R339L	339	Missense	distal	4	no	13.059	13.218	PhosphoSitePlus	ICGC;COSMIC	9.540	Up-regulation
Atypical_PIKK_ATM_ATM_ST	Q969R5	L3MBTL2	Q13315	ATM	S335	R341L	341	Missense	distal	6	no	13.059	13.020	PhosphoSitePlus	ICGC	9.540	Down-regulation
Atypical_PIKK_ATM_ATM_ST	Q969R5	L3MBTL2	Q13315	ATM	S335	R328Q	328	Missense	distal	-7	no	13.059	13.258	PhosphoSitePlus	ICGC	9.540	Up-regulation
Atypical_PIKK_ATM_ATM_ST	Q969R5	L3MBTL2	Q13315	ATM	T611	P612Q	612	Missense	proximal	1	no	5.646	10.447	EPSD	ICGC;COSMIC	9.540	Gain
Atypical_PIKK_ATM_ATM_ST	Q969R5	L3MBTL2	Q13315	ATM	S683	E677D	677	Missense	distal	-6	no	9.759	9.545	EPSD	ICGC;COSMIC	9.540	Down-regulation
Atypical_PIKK_ATM_ATM_ST	Q9Y4E8	USP15	Q13315	ATM	T11	D8H	8	Missense	distal	-3	no	11.376	11.224	EPSD	ICGC	9.540	Down-regulation
Atypical_PIKK_ATM_ATM_ST	Q9Y4E8	USP15	Q13315	ATM	T11	R13W	13	Missense	proximal	2	no	11.376	11.055	EPSD	ICGC;COSMIC	9.540	Down-regulation
Atypical_PIKK_ATM_ATM_ST	Q9Y4E8	USP15	Q13315	ATM	S229	G231C	231	Missense	proximal	2	no	9.671	9.276	EPSD	ICGC	9.540	Loss
Atypical_PIKK_ATM_ATM_ST	Q9Y4E8	USP15	Q13315	ATM	S961	D967E	967	Missense	distal	6	no	11.302	11.349	EPSD	ICGC;COSMIC	9.540	Up-regulation
Atypical_PIKK_ATM_ATM_ST	Q8IW19	APLF	Q13315	ATM	S144	G142C	142	Missense	proximal	-2	no	11.874	11.855	EPSD	ICGC;COSMIC	9.540	Down-regulation
Atypical_PIKK_ATM_ATM_ST	Q9Y2K7	KDM2A	Q13315	ATM	S11	T17A	17	Missense	distal	6	no	15.759	15.775	EPSD	ICGC;COSMIC	9.540	Up-regulation
Atypical_PIKK_ATM_ATM_ST	Q9Y2K7	KDM2A	Q13315	ATM	S11	S11I	11	Missense	central	0	yes	15.759	0.000	EPSD	ICGC	9.540	Loss
Atypical_PIKK_ATM_ATM_ST	Q9Y2K7	KDM2A	Q13315	ATM	S11	R13I	13	Missense	proximal	2	no	15.759	16.072	EPSD	ICGC	9.540	Up-regulation
Atypical_PIKK_ATM_ATM_ST	Q9Y2K7	KDM2A	Q13315	ATM	S11	Y10H	10	Missense	proximal	-1	no	15.759	15.603	EPSD	ICGC;COSMIC	9.540	Down-regulation
Atypical_PIKK_ATM_ATM_ST	Q9Y2K7	KDM2A	Q13315	ATM	S81	L84I	84	Missense	distal	3	no	10.764	10.983	EPSD	ICGC;COSMIC	9.540	Up-regulation
Atypical_PIKK_ATM_ATM_ST	Q9Y2K7	KDM2A	Q13315	ATM	T115	M111I	111	Missense	distal	-4	no	11.997	12.293	EPSD	ICGC	9.540	Up-regulation
Atypical_PIKK_ATM_ATM_ST	Q9Y2K7	KDM2A	Q13315	ATM	T115	V113M	113	Missense	proximal	-2	no	11.997	12.224	EPSD	ICGC;COSMIC	9.540	Up-regulation
Atypical_PIKK_ATM_ATM_ST	Q9Y2K7	KDM2A	Q13315	ATM	S180	E183D	183	Missense	distal	3	no	14.708	15.067	EPSD	ICGC;COSMIC	9.540	Up-regulation
Atypical_PIKK_ATM_ATM_ST	Q9Y2K7	KDM2A	Q13315	ATM	S394	A397T	397	Missense	distal	3	no	10.277	10.302	EPSD	ICGC	9.540	Up-regulation
Atypical_PIKK_ATM_ATM_ST	Q9Y2K7	KDM2A	Q13315	ATM	S797	K793N	793	Missense	distal	-4	no	9.600	9.365	EPSD	ICGC;COSMIC	9.540	Loss
Atypical_PIKK_ATM_ATM_ST	Q02535	ID3	Q13315	ATM	S65	L70V	70	Missense	distal	5	no	14.211	14.259	PhosphoSitePlus	ICGC;COSMIC;GDSC;CCLE	9.540	Up-regulation
Atypical_PIKK_ATM_ATM_ST	Q02535	ID3	Q13315	ATM	S65	L64F	64	Missense	proximal	-1	no	14.211	13.920	PhosphoSitePlus	ICGC;COSMIC;GDSC;CCLE	9.540	Down-regulation
Atypical_PIKK_ATM_ATM_ST	Q02535	ID3	Q13315	ATM	S65	L64V	64	Missense	proximal	-1	no	14.211	13.923	PhosphoSitePlus	ICGC;COSMIC	9.540	Down-regulation
Atypical_PIKK_ATM_ATM_ST	Q02535	ID3	Q13315	ATM	S65	Q63H	63	Missense	proximal	-2	no	14.211	13.908	PhosphoSitePlus	ICGC	9.540	Down-regulation
Atypical_PIKK_ATM_ATM_ST	P46379	BAG6	Q13315	ATM	S104	H109D	109	Missense	distal	5	no	10.760	10.707	EPSD	ICGC;COSMIC	9.540	Down-regulation
Atypical_PIKK_ATM_ATM_ST	P46379	BAG6	Q13315	ATM	S104	T102M	102	Missense	proximal	-2	no	10.760	10.410	EPSD	ICGC;COSMIC	9.540	Down-regulation
Atypical_PIKK_ATM_ATM_ST	P46379	BAG6	Q13315	ATM	S113	H109D	109	Missense	distal	-4	no	9.273	9.948	EPSD	ICGC;COSMIC	9.540	Gain
Atypical_PIKK_ATM_ATM_ST	P46379	BAG6	Q13315	ATM	S697	S697L	697	Missense	central	0	yes	10.183	0.000	EPSD	ICGC;COSMIC	9.540	Loss
Atypical_PIKK_ATM_ATM_ST	Q9NUW8	TDP1	Q13315	ATM	S18	S18N	18	Missense	central	0	yes	9.644	0.000	EPSD	ICGC;COSMIC	9.540	Loss
Atypical_PIKK_ATM_ATM_ST	Q9NUW8	TDP1	Q13315	ATM	S18	D16Y	16	Missense	proximal	-2	no	9.644	9.773	EPSD	ICGC	9.540	Up-regulation
Atypical_PIKK_ATM_ATM_ST	Q9NUW8	TDP1	Q13315	ATM	S18	S13F	13	Missense	distal	-5	no	9.644	9.968	EPSD	ICGC;COSMIC;GDSC;CCLE	9.540	Up-regulation
Atypical_PIKK_ATM_ATM_ST	Q9NUW8	TDP1	Q13315	ATM	T30	S31Y	31	Missense	proximal	1	no	3.696	9.758	EPSD	ICGC;COSMIC	9.540	Gain
Atypical_PIKK_ATM_ATM_ST	Q9NUW8	TDP1	Q13315	ATM	S61	H56Q	56	Missense	distal	-5	no	9.920	9.738	EPSD	ICGC;COSMIC	9.540	Down-regulation
Atypical_PIKK_ATM_ATM_ST	Q9NUW8	TDP1	Q13315	ATM	S148	Q152H	152	Missense	distal	4	no	11.780	11.865	EPSD	ICGC	9.540	Up-regulation
Atypical_PIKK_ATM_ATM_ST	Q9NUW8	TDP1	Q13315	ATM	S365	R361H	361	Missense	distal	-4	no	18.601	18.732	PhosphoSitePlus;EPSD	ICGC	9.540	Up-regulation
Atypical_PIKK_ATM_ATM_ST	Q9NUW8	TDP1	Q13315	ATM	S563	A561S	561	Missense	proximal	-2	no	17.540	17.727	EPSD;PhosphoSitePlus	ICGC;COSMIC	9.540	Up-regulation
Atypical_PIKK_ATM_ATM_ST	Q9NUW8	TDP1	Q13315	ATM	S563	A568S	568	Missense	distal	5	no	17.540	17.492	EPSD;PhosphoSitePlus	ICGC	9.540	Down-regulation
Atypical_PIKK_ATM_ATM_ST	Q9NUW8	TDP1	Q13315	ATM	S563	A568T	568	Missense	distal	5	no	17.540	17.475	EPSD;PhosphoSitePlus	ICGC	9.540	Down-regulation
Atypical_PIKK_ATM_ATM_ST	Q14683	SMC1A	Q13315	ATM	S85	A89D	89	Missense	distal	4	no	10.883	11.438	EPSD	ICGC	9.540	Up-regulation
Atypical_PIKK_ATM_ATM_ST	Q14683	SMC1A	Q13315	ATM	T182	V176A	176	Missense	distal	-6	no	12.377	12.613	EPSD	ICGC	9.540	Up-regulation
Atypical_PIKK_ATM_ATM_ST	Q14683	SMC1A	Q13315	ATM	T182	A178V	178	Missense	distal	-4	no	12.377	11.898	EPSD	ICGC;COSMIC;GDSC;CCLE	9.540	Down-regulation
Atypical_PIKK_ATM_ATM_ST	Q14683	SMC1A	Q13315	ATM	S289	E290Q	290	Missense	proximal	1	no	7.169	13.065	EPSD	ICGC;COSMIC	9.540	Gain
Atypical_PIKK_ATM_ATM_ST	Q14683	SMC1A	Q13315	ATM	S358	G362R	362	Missense	distal	4	no	15.601	15.654	EPSD	ICGC	9.540	Up-regulation
Atypical_PIKK_ATM_ATM_ST	Q14683	SMC1A	Q13315	ATM	S360	G362R	362	Missense	proximal	2	no	15.422	15.283	EPSD	ICGC	9.540	Down-regulation
Atypical_PIKK_ATM_ATM_ST	Q14683	SMC1A	Q13315	ATM	S703	A705D	705	Missense	proximal	2	no	15.804	16.767	EPSD	ICGC	9.540	Up-regulation
Atypical_PIKK_ATM_ATM_ST	Q14683	SMC1A	Q13315	ATM	S703	Q702H	702	Missense	proximal	-1	no	15.804	15.667	EPSD	ICGC;COSMIC	9.540	Down-regulation
Atypical_PIKK_ATM_ATM_ST	Q14683	SMC1A	Q13315	ATM	S715	R711L	711	Missense	distal	-4	no	13.230	13.101	EPSD	ICGC;COSMIC	9.540	Down-regulation
Atypical_PIKK_ATM_ATM_ST	Q14683	SMC1A	Q13315	ATM	S951	S956I	956	Missense	distal	5	no	12.066	12.276	EPSD	ICGC;COSMIC	9.540	Up-regulation
Atypical_PIKK_ATM_ATM_ST	Q14683	SMC1A	Q13315	ATM	S957	S956I	956	Missense	proximal	-1	no	14.210	13.989	PhosphoSitePlus;EPSD	ICGC;COSMIC	9.540	Down-regulation
Atypical_PIKK_ATM_ATM_ST	P54132	BLM	Q13315	ATM	S74	E69K	69	Missense	distal	-5	no	13.187	13.269	EPSD	ICGC;COSMIC	9.540	Up-regulation
Atypical_PIKK_ATM_ATM_ST	P54132	BLM	Q13315	ATM	T99	P94S	94	Missense	distal	-5	no	13.631	13.627	EPSD;PhosphoSitePlus	ICGC	9.540	Down-regulation
Atypical_PIKK_ATM_ATM_ST	P54132	BLM	Q13315	ATM	S144	S147Y	147	Missense	distal	3	no	11.497	11.739	EPSD	ICGC	9.540	Up-regulation
Atypical_PIKK_ATM_ATM_ST	P54132	BLM	Q13315	ATM	S166	D161Y	161	Missense	distal	-5	no	9.902	10.137	EPSD	ICGC	9.540	Up-regulation
Atypical_PIKK_ATM_ATM_ST	P54132	BLM	Q13315	ATM	T283	V286F	286	Missense	distal	3	no	9.362	9.600	EPSD	ICGC	9.540	Gain
Atypical_PIKK_ATM_ATM_ST	P54132	BLM	Q13315	ATM	S367	Q365L	365	Missense	proximal	-2	no	9.618	9.352	EPSD	ICGC;COSMIC	9.540	Loss
Atypical_PIKK_ATM_ATM_ST	P54132	BLM	Q13315	ATM	S646	R643H	643	Missense	distal	-3	no	10.302	9.657	EPSD	ICGC;COSMIC;GDSC	9.540	Down-regulation
Atypical_PIKK_ATM_ATM_ST	P54132	BLM	Q13315	ATM	S646	Q645K	645	Missense	proximal	-1	no	10.302	10.177	EPSD	ICGC;COSMIC	9.540	Down-regulation
Atypical_PIKK_ATM_ATM_ST	P54132	BLM	Q13315	ATM	S646	R643L	643	Missense	distal	-3	no	10.302	9.771	EPSD	ICGC;COSMIC	9.540	Down-regulation
Atypical_PIKK_ATM_ATM_ST	P54132	BLM	Q13315	ATM	S646	S648N	648	Missense	proximal	2	no	10.302	9.661	EPSD	ICGC	9.540	Down-regulation
Atypical_PIKK_ATM_ATM_ST	P54132	BLM	Q13315	ATM	S706	A703V	703	Missense	distal	-3	no	8.830	9.694	EPSD	ICGC;COSMIC	9.540	Gain
Atypical_PIKK_ATM_ATM_ST	P54132	BLM	Q13315	ATM	T830	R836M	836	Missense	distal	6	no	9.736	9.724	EPSD	ICGC;COSMIC	9.540	Down-regulation
Atypical_PIKK_ATM_ATM_ST	P54132	BLM	Q13315	ATM	T830	V837L	837	Missense	distal	7	no	9.736	9.706	EPSD	ICGC;COSMIC	9.540	Down-regulation
Atypical_PIKK_ATM_ATM_ST	P54132	BLM	Q13315	ATM	T830	A833S	833	Missense	distal	3	no	9.736	9.680	EPSD	ICGC	9.540	Down-regulation
Atypical_PIKK_ATM_ATM_ST	P54132	BLM	Q13315	ATM	T830	T830M	830	Missense	central	0	yes	9.736	0.000	EPSD	ICGC;COSMIC	9.540	Loss
Atypical_PIKK_ATM_ATM_ST	P54132	BLM	Q13315	ATM	S1252	A1250S	1250	Missense	proximal	-2	no	9.469	9.656	EPSD	ICGC	9.540	Gain
Atypical_PIKK_ATM_ATM_ST	P54132	BLM	Q13315	ATM	S1290	P1297Q	1297	Missense	distal	7	no	10.693	10.685	EPSD	ICGC;COSMIC	9.540	Down-regulation
Atypical_PIKK_ATM_ATM_ST	P54132	BLM	Q13315	ATM	S1296	P1297Q	1297	Missense	proximal	1	no	7.369	12.171	EPSD	ICGC;COSMIC	9.540	Gain
Atypical_PIKK_ATM_ATM_ST	Q14190	SIM2	Q13315	ATM	S35	A32S	32	Missense	distal	-3	no	14.063	14.508	EPSD	ICGC	9.540	Up-regulation
Atypical_PIKK_ATM_ATM_ST	Q14190	SIM2	Q13315	ATM	S35	Q36H	36	Missense	proximal	1	no	14.063	-0.846	EPSD	ICGC	9.540	Loss
Atypical_PIKK_ATM_ATM_ST	Q14190	SIM2	Q13315	ATM	S115	N122H	122	Missense	distal	7	no	11.783	11.797	PhosphoSitePlus	ICGC	9.540	Up-regulation
Atypical_PIKK_ATM_ATM_ST	Q14190	SIM2	Q13315	ATM	S115	A108T	108	Missense	distal	-7	no	11.783	11.799	PhosphoSitePlus	ICGC;COSMIC	9.540	Up-regulation
Atypical_PIKK_ATM_ATM_ST	Q14190	SIM2	Q13315	ATM	S115	S115F	115	Missense	central	0	yes	11.783	0.000	PhosphoSitePlus	ICGC	9.540	Loss
Atypical_PIKK_ATM_ATM_ST	Q14190	SIM2	Q13315	ATM	S186	R192S	192	Missense	distal	6	no	10.241	10.259	EPSD	ICGC	9.540	Up-regulation
Atypical_PIKK_ATM_ATM_ST	Q14190	SIM2	Q13315	ATM	S186	C185F	185	Missense	proximal	-1	no	10.241	10.014	EPSD	ICGC	9.540	Down-regulation
Atypical_PIKK_ATM_ATM_ST	Q14190	SIM2	Q13315	ATM	S186	V182F	182	Missense	distal	-4	no	10.241	9.831	EPSD	ICGC	9.540	Down-regulation
Atypical_PIKK_ATM_ATM_ST	Q14190	SIM2	Q13315	ATM	S237	D239Y	239	Missense	proximal	2	no	11.214	9.973	EPSD	ICGC;COSMIC	9.540	Down-regulation
Atypical_PIKK_ATM_ATM_ST	Q14190	SIM2	Q13315	ATM	S237	M231I	231	Missense	distal	-6	no	11.214	11.059	EPSD	ICGC;COSMIC	9.540	Down-regulation
Atypical_PIKK_ATM_ATM_ST	Q14190	SIM2	Q13315	ATM	S237	L242M	242	Missense	distal	5	no	11.214	11.235	EPSD	ICGC;COSMIC	9.540	Up-regulation
Atypical_PIKK_ATM_ATM_ST	Q14190	SIM2	Q13315	ATM	S471	G470R	470	Missense	proximal	-1	no	9.969	9.786	EPSD	ICGC	9.540	Down-regulation
Atypical_PIKK_ATM_ATM_ST	Q14190	SIM2	Q13315	ATM	S523	E525K	525	Missense	proximal	2	no	10.969	9.638	EPSD	ICGC;COSMIC;GDSC;CCLE	9.540	Down-regulation
Atypical_PIKK_ATM_ATM_ST	P54274	TERF1	Q13315	ATM	T24	D22N	22	Missense	proximal	-2	no	9.596	9.715	EPSD	ICGC;COSMIC	9.540	Up-regulation
Atypical_PIKK_ATM_ATM_ST	P54274	TERF1	Q13315	ATM	T24	E26K	26	Missense	proximal	2	no	9.596	8.266	EPSD	ICGC	9.540	Loss
Atypical_PIKK_ATM_ATM_ST	P54274	TERF1	Q13315	ATM	T24	G18N	18	Missense	distal	-6	no	9.596	9.682	EPSD	ICGC	9.540	Up-regulation
Atypical_PIKK_ATM_ATM_ST	P54274	TERF1	Q13315	ATM	T24	D17N	17	Missense	distal	-7	no	9.596	9.632	EPSD	ICGC;GDSC;CCLE	9.540	Up-regulation
Atypical_PIKK_ATM_ATM_ST	P54274	TERF1	Q13315	ATM	S114	A117S	117	Missense	distal	3	no	9.744	9.689	EPSD	ICGC	9.540	Down-regulation
Atypical_PIKK_ATM_ATM_ST	P54274	TERF1	Q13315	ATM	S219	S219Y	219	Missense	central	0	yes	14.562	0.000	EPSD;PhosphoSitePlus	ICGC;COSMIC	9.540	Loss
Atypical_PIKK_ATM_ATM_ST	Q14161	GIT2	Q13315	ATM	S8	E9Q	9	Missense	proximal	1	no	6.246	12.142	EPSD	ICGC;COSMIC	9.540	Gain
Atypical_PIKK_ATM_ATM_ST	Q14161	GIT2	Q13315	ATM	S20	W21L	21	Missense	proximal	1	no	4.493	10.741	EPSD	ICGC;COSMIC	9.540	Gain
Atypical_PIKK_ATM_ATM_ST	Q14161	GIT2	Q13315	ATM	S46	R39W	39	Missense	distal	-7	no	12.860	12.670	EPSD	ICGC;COSMIC	9.540	Down-regulation
Atypical_PIKK_ATM_ATM_ST	Q14161	GIT2	Q13315	ATM	T195	D192E	192	Missense	distal	-3	no	13.965	13.559	EPSD;PhosphoSitePlus	ICGC	9.540	Down-regulation
Atypical_PIKK_ATM_ATM_ST	Q14161	GIT2	Q13315	ATM	T195	A191E	191	Missense	distal	-4	no	13.965	14.753	EPSD;PhosphoSitePlus	ICGC	9.540	Up-regulation
Atypical_PIKK_ATM_ATM_ST	Q14161	GIT2	Q13315	ATM	S384	P390H	390	Missense	distal	6	no	14.262	14.240	PhosphoSitePlus;EPSD	ICGC	9.540	Down-regulation
Atypical_PIKK_ATM_ATM_ST	Q14161	GIT2	Q13315	ATM	S415	L416I	416	Missense	proximal	1	no	12.027	1.658	EPSD	ICGC;COSMIC	9.540	Loss
Atypical_PIKK_ATM_ATM_ST	Q14161	GIT2	Q13315	ATM	S421	L416I	416	Missense	distal	-5	no	9.490	9.582	EPSD	ICGC;COSMIC	9.540	Gain
Atypical_PIKK_ATM_ATM_ST	Q14161	GIT2	Q13315	ATM	S590	D591Y	591	Missense	proximal	1	no	10.566	10.881	EPSD	ICGC	9.540	Up-regulation
Atypical_PIKK_ATM_ATM_ST	Q14161	GIT2	Q13315	ATM	S634	S634P	634	Missense	central	0	yes	10.775	0.000	EPSD	ICGC;COSMIC	9.540	Loss
Atypical_PIKK_ATM_ATM_ST	Q14161	GIT2	Q13315	ATM	S634	A632V	632	Missense	proximal	-2	no	10.775	10.298	EPSD	ICGC;COSMIC	9.540	Down-regulation
Atypical_PIKK_ATM_ATM_ST	Q14161	GIT2	Q13315	ATM	S634	A627E	627	Missense	distal	-7	no	10.775	11.228	EPSD	ICGC	9.540	Up-regulation
Atypical_PIKK_ATM_ATM_ST	Q14161	GIT2	Q13315	ATM	T732	T732M	732	Missense	central	0	yes	11.112	0.000	EPSD	ICGC	9.540	Loss
Atypical_PIKK_ATM_ATM_ST	Q14161	GIT2	Q13315	ATM	T732	Q737K	737	Missense	distal	5	no	11.112	11.063	EPSD	ICGC;COSMIC	9.540	Down-regulation
Atypical_PIKK_ATM_ATM_ST	Q5XUX0	FBXO31	Q13315	ATM	S278	M272L	272	Missense	distal	-6	no	13.114	13.071	PhosphoSitePlus	ICGC;COSMIC	9.540	Down-regulation
Atypical_PIKK_ATM_ATM_ST	Q5XUX0	FBXO31	Q13315	ATM	S278	C283Y	283	Missense	distal	5	no	13.114	12.952	PhosphoSitePlus	ICGC;COSMIC	9.540	Down-regulation
Atypical_PIKK_ATM_ATM_ST	Q5XUX0	FBXO31	Q13315	ATM	S278	F274S	274	Missense	distal	-4	no	13.114	14.513	PhosphoSitePlus	ICGC;COSMIC	9.540	Up-regulation
Atypical_PIKK_ATM_ATM_ST	Q5XUX0	FBXO31	Q13315	ATM	S278	L284P	284	Missense	distal	6	no	13.114	13.159	PhosphoSitePlus	ICGC;COSMIC	9.540	Up-regulation
Atypical_PIKK_ATM_ATM_ST	Q5XUX0	FBXO31	Q13315	ATM	S400	P397F	397	Missense	distal	-3	no	14.920	15.796	EPSD	ICGC	9.540	Up-regulation
Atypical_PIKK_ATM_ATM_ST	Q5XUX0	FBXO31	Q13315	ATM	S403	R408M	408	Missense	distal	5	no	11.239	11.258	EPSD	ICGC;COSMIC	9.540	Up-regulation
Atypical_PIKK_ATM_ATM_ST	Q5XUX0	FBXO31	Q13315	ATM	S403	P397F	397	Missense	distal	-6	no	11.239	10.766	EPSD	ICGC	9.540	Down-regulation
Atypical_PIKK_ATM_ATM_ST	Q92905	COPS5	Q13315	ATM	S270	D268E	268	Missense	proximal	-2	no	9.440	9.919	EPSD	ICGC;COSMIC	9.540	Gain
Atypical_PIKK_ATM_ATM_ST	Q92905	COPS5	Q13315	ATM	S276	R282Q	282	Missense	distal	6	no	10.226	10.222	EPSD	ICGC	9.540	Down-regulation
Atypical_PIKK_ATM_ATM_ST	P15336	ATF2	Q13315	ATM	S328	S321G	321	Missense	distal	-7	no	10.429	9.917	EPSD	ICGC;COSMIC	9.540	Down-regulation
Atypical_PIKK_ATM_ATM_ST	P15336	ATF2	Q13315	ATM	T336	S340L	340	Missense	distal	4	no	12.972	13.313	EPSD	ICGC;COSMIC	9.540	Up-regulation
Atypical_PIKK_ATM_ATM_ST	P15336	ATF2	Q13315	ATM	T336	Q337H	337	Missense	proximal	1	no	12.972	-1.937	EPSD	ICGC;COSMIC	9.540	Loss
Atypical_PIKK_ATM_ATM_ST	Q14676	MDC1	Q13315	ATM	S21	R25M	25	Missense	distal	4	no	11.922	12.000	EPSD	ICGC	9.540	Up-regulation
Atypical_PIKK_ATM_ATM_ST	Q14676	MDC1	Q13315	ATM	S23	R25M	25	Missense	proximal	2	no	11.007	10.948	EPSD	ICGC	9.540	Down-regulation
Atypical_PIKK_ATM_ATM_ST	Q14676	MDC1	Q13315	ATM	S292	D298N	298	Missense	distal	6	no	14.824	14.835	EPSD	ICGC;COSMIC	9.540	Up-regulation
Atypical_PIKK_ATM_ATM_ST	Q14676	MDC1	Q13315	ATM	T341	I338M	338	Missense	distal	-3	no	9.811	9.496	EPSD	ICGC;COSMIC	9.540	Loss
Atypical_PIKK_ATM_ATM_ST	Q14676	MDC1	Q13315	ATM	S372	E371K	371	Missense	proximal	-1	no	13.561	13.158	EPSD	ICGC;COSMIC	9.540	Down-regulation
Atypical_PIKK_ATM_ATM_ST	Q14676	MDC1	Q13315	ATM	S372	H368N	368	Missense	distal	-4	no	13.561	13.312	EPSD	ICGC;COSMIC	9.540	Down-regulation
Atypical_PIKK_ATM_ATM_ST	Q14676	MDC1	Q13315	ATM	S422	W427L	427	Missense	distal	5	no	13.385	13.360	EPSD	ICGC;COSMIC	9.540	Down-regulation
Atypical_PIKK_ATM_ATM_ST	Q14676	MDC1	Q13315	ATM	S445	D452G	452	Missense	distal	7	no	12.523	12.556	EPSD	ICGC	9.540	Up-regulation
Atypical_PIKK_ATM_ATM_ST	Q14676	MDC1	Q13315	ATM	S445	S445R	445	Missense	central	0	yes	12.523	0.000	EPSD	ICGC;COSMIC	9.540	Loss
Atypical_PIKK_ATM_ATM_ST	Q14676	MDC1	Q13315	ATM	S598	G604R	604	Missense	distal	6	no	14.446	14.447	EPSD	ICGC;COSMIC	9.540	Up-regulation
Atypical_PIKK_ATM_ATM_ST	Q14676	MDC1	Q13315	ATM	S641	E643Q	643	Missense	proximal	2	no	9.770	8.957	EPSD	ICGC;COSMIC	9.540	Loss
Atypical_PIKK_ATM_ATM_ST	Q14676	MDC1	Q13315	ATM	T659	G665E	665	Missense	distal	6	no	13.856	13.899	EPSD	ICGC;COSMIC	9.540	Up-regulation
Atypical_PIKK_ATM_ATM_ST	Q14676	MDC1	Q13315	ATM	T659	A666P	666	Missense	distal	7	no	13.856	13.844	EPSD	ICGC;COSMIC	9.540	Down-regulation
Atypical_PIKK_ATM_ATM_ST	Q14676	MDC1	Q13315	ATM	T659	L655I	655	Missense	distal	-4	no	13.856	14.083	EPSD	ICGC	9.540	Up-regulation
Atypical_PIKK_ATM_ATM_ST	Q14676	MDC1	Q13315	ATM	T752	W747L	747	Missense	distal	-5	no	14.997	14.778	EPSD	ICGC;COSMIC	9.540	Down-regulation
Atypical_PIKK_ATM_ATM_ST	Q14676	MDC1	Q13315	ATM	T765	D769G	769	Missense	distal	4	no	12.124	12.046	EPSD	ICGC;COSMIC	9.540	Down-regulation
Atypical_PIKK_ATM_ATM_ST	Q14676	MDC1	Q13315	ATM	S780	P782L	782	Missense	proximal	2	no	9.675	8.886	EPSD	ICGC	9.540	Loss
Atypical_PIKK_ATM_ATM_ST	Q14676	MDC1	Q13315	ATM	S882	P883S	883	Missense	proximal	1	no	9.638	2.662	EPSD	ICGC;COSMIC	9.540	Loss
Atypical_PIKK_ATM_ATM_ST	Q14676	MDC1	Q13315	ATM	T946	E952Q	952	Missense	distal	6	no	12.717	12.670	EPSD	ICGC;COSMIC	9.540	Down-regulation
Atypical_PIKK_ATM_ATM_ST	Q14676	MDC1	Q13315	ATM	S955	E952Q	952	Missense	distal	-3	no	15.531	15.655	EPSD	ICGC;COSMIC	9.540	Up-regulation
Atypical_PIKK_ATM_ATM_ST	Q14676	MDC1	Q13315	ATM	S964	E968K	968	Missense	distal	4	no	10.295	10.672	EPSD	ICGC;COSMIC	9.540	Up-regulation
Atypical_PIKK_ATM_ATM_ST	Q14676	MDC1	Q13315	ATM	S964	T966K	966	Missense	proximal	2	no	10.295	9.737	EPSD	ICGC;COSMIC	9.540	Down-regulation
Atypical_PIKK_ATM_ATM_ST	Q14676	MDC1	Q13315	ATM	S964	P969T	969	Missense	distal	5	no	10.295	10.097	EPSD	ICGC	9.540	Down-regulation
Atypical_PIKK_ATM_ATM_ST	Q14676	MDC1	Q13315	ATM	S988	G987R	987	Missense	proximal	-1	no	12.287	12.104	EPSD	ICGC;COSMIC	9.540	Down-regulation
Atypical_PIKK_ATM_ATM_ST	Q14676	MDC1	Q13315	ATM	S1057	P1063S	1063	Missense	distal	6	no	13.905	13.916	EPSD	ICGC	9.540	Up-regulation
Atypical_PIKK_ATM_ATM_ST	Q14676	MDC1	Q13315	ATM	S1184	T1187A	1187	Missense	distal	3	no	13.570	13.545	EPSD	ICGC	9.540	Down-regulation
Atypical_PIKK_ATM_ATM_ST	Q14676	MDC1	Q13315	ATM	T1198	S1194Y	1194	Missense	distal	-4	no	10.825	9.724	EPSD	ICGC	9.540	Down-regulation
Atypical_PIKK_ATM_ATM_ST	Q14676	MDC1	Q13315	ATM	T1280	S1276P	1276	Missense	distal	-4	no	10.583	9.914	EPSD	ICGC	9.540	Down-regulation
Atypical_PIKK_ATM_ATM_ST	Q14676	MDC1	Q13315	ATM	T1526	S1522P	1522	Missense	distal	-4	no	10.241	9.571	EPSD	ICGC	9.540	Down-regulation
Atypical_PIKK_ATM_ATM_ST	Q14676	MDC1	Q13315	ATM	T1716	P1709S	1709	Missense	distal	-7	no	11.815	12.051	EPSD	ICGC	9.540	Up-regulation
Atypical_PIKK_ATM_ATM_ST	Q14676	MDC1	Q13315	ATM	S1820	L1815I	1815	Missense	distal	-5	no	9.767	9.859	EPSD	ICGC	9.540	Up-regulation
Atypical_PIKK_ATM_ATM_ST	Q14676	MDC1	Q13315	ATM	S1820	M1818T	1818	Missense	proximal	-2	no	9.767	10.117	EPSD	ICGC;COSMIC	9.540	Up-regulation
Atypical_PIKK_ATM_ATM_ST	Q9H7Z6	KAT8	Q13315	ATM	S42	P36A	36	Missense	distal	-6	no	11.225	11.264	EPSD	ICGC;COSMIC	9.540	Up-regulation
Atypical_PIKK_ATM_ATM_ST	Q9H7Z6	KAT8	Q13315	ATM	S42	P43A	43	Missense	proximal	1	no	11.225	9.154	EPSD	ICGC	9.540	Loss
Atypical_PIKK_ATM_ATM_ST	Q9H7Z6	KAT8	Q13315	ATM	S348	E350A	350	Missense	proximal	2	no	10.635	9.542	EPSD	ICGC;COSMIC	9.540	Down-regulation
Atypical_PIKK_ATM_ATM_ST	Q9H7Z6	KAT8	Q13315	ATM	S348	P352L	352	Missense	distal	4	no	10.635	10.854	EPSD	ICGC	9.540	Up-regulation
Atypical_PIKK_ATM_ATM_ST	Q14694	USP10	Q13315	ATM	T74	D69H	69	Missense	distal	-5	no	11.682	11.941	EPSD	ICGC;COSMIC	9.540	Up-regulation
Atypical_PIKK_ATM_ATM_ST	Q14694	USP10	Q13315	ATM	S76	D69H	69	Missense	distal	-7	no	9.841	9.750	EPSD	ICGC;COSMIC	9.540	Down-regulation
Atypical_PIKK_ATM_ATM_ST	Q14694	USP10	Q13315	ATM	S211	V204L	204	Missense	distal	-7	no	9.560	9.452	EPSD	ICGC;COSMIC	9.540	Loss
Atypical_PIKK_ATM_ATM_ST	Q14694	USP10	Q13315	ATM	S321	T327M	327	Missense	distal	6	no	10.326	10.306	EPSD	ICGC;COSMIC	9.540	Down-regulation
Atypical_PIKK_ATM_ATM_ST	Q14694	USP10	Q13315	ATM	S321	A324P	324	Missense	distal	3	no	10.326	10.422	EPSD	ICGC;COSMIC	9.540	Up-regulation
Atypical_PIKK_ATM_ATM_ST	Q14694	USP10	Q13315	ATM	S321	A320S	320	Missense	proximal	-1	no	10.326	10.486	EPSD	ICGC	9.540	Up-regulation
Atypical_PIKK_ATM_ATM_ST	Q14694	USP10	Q13315	ATM	S331	T327M	327	Missense	distal	-4	no	10.845	10.220	EPSD	ICGC;COSMIC	9.540	Down-regulation
Atypical_PIKK_ATM_ATM_ST	Q14694	USP10	Q13315	ATM	S331	A324P	324	Missense	distal	-7	no	10.845	10.705	EPSD	ICGC;COSMIC	9.540	Down-regulation
Atypical_PIKK_ATM_ATM_ST	Q14694	USP10	Q13315	ATM	S355	S353Y	353	Missense	proximal	-2	no	10.172	10.003	EPSD	ICGC;COSMIC	9.540	Down-regulation
Atypical_PIKK_ATM_ATM_ST	Q09472	EP300	Q13315	ATM	S20	S24L	24	Missense	distal	4	no	9.820	10.162	EPSD	ICGC;COSMIC	9.540	Up-regulation
Atypical_PIKK_ATM_ATM_ST	Q09472	EP300	Q13315	ATM	S26	S24L	24	Missense	proximal	-2	no	10.301	9.911	EPSD	ICGC;COSMIC	9.540	Down-regulation
Atypical_PIKK_ATM_ATM_ST	Q09472	EP300	Q13315	ATM	S106	S106C	106	Missense	central	0	yes	15.018	0.000	PhosphoSitePlus	ICGC;COSMIC	9.540	Loss
Atypical_PIKK_ATM_ATM_ST	Q09472	EP300	Q13315	ATM	S227	Q224H	224	Missense	distal	-3	no	9.466	9.596	EPSD	ICGC	9.540	Gain
Atypical_PIKK_ATM_ATM_ST	Q09472	EP300	Q13315	ATM	S384	V390G	390	Missense	distal	6	no	9.803	9.808	EPSD	ICGC;COSMIC	9.540	Up-regulation
Atypical_PIKK_ATM_ATM_ST	Q09472	EP300	Q13315	ATM	S384	H378N	378	Missense	distal	-6	no	9.803	9.866	EPSD	ICGC;COSMIC	9.540	Up-regulation
Atypical_PIKK_ATM_ATM_ST	Q09472	EP300	Q13315	ATM	S831	R838C	838	Missense	distal	7	no	9.885	9.903	EPSD	ICGC;COSMIC	9.540	Up-regulation
Atypical_PIKK_ATM_ATM_ST	Q09472	EP300	Q13315	ATM	S831	L827R	827	Missense	distal	-4	no	9.885	10.014	EPSD	ICGC	9.540	Up-regulation
Atypical_PIKK_ATM_ATM_ST	Q09472	EP300	Q13315	ATM	T992	Q986L	986	Missense	distal	-6	no	12.510	12.259	EPSD	ICGC;COSMIC	9.540	Down-regulation
Atypical_PIKK_ATM_ATM_ST	Q09472	EP300	Q13315	ATM	T992	I997V	997	Missense	distal	5	no	12.510	12.512	EPSD	ICGC;COSMIC	9.540	Up-regulation
Atypical_PIKK_ATM_ATM_ST	Q09472	EP300	Q13315	ATM	T1035	P1039S	1039	Missense	distal	4	no	14.535	14.412	EPSD	ICGC;COSMIC	9.540	Down-regulation
Atypical_PIKK_ATM_ATM_ST	Q09472	EP300	Q13315	ATM	T1035	S1033L	1033	Missense	proximal	-2	no	14.535	14.145	EPSD	ICGC;COSMIC	9.540	Down-regulation
Atypical_PIKK_ATM_ATM_ST	Q09472	EP300	Q13315	ATM	T1035	Q1036K	1036	Missense	proximal	1	no	14.535	7.687	EPSD	ICGC;COSMIC	9.540	Loss
Atypical_PIKK_ATM_ATM_ST	Q09472	EP300	Q13315	ATM	S1038	P1039S	1039	Missense	proximal	1	no	11.552	4.577	EPSD	ICGC;COSMIC	9.540	Loss
Atypical_PIKK_ATM_ATM_ST	Q09472	EP300	Q13315	ATM	S1038	S1033L	1033	Missense	distal	-5	no	11.552	11.575	EPSD	ICGC;COSMIC	9.540	Up-regulation
Atypical_PIKK_ATM_ATM_ST	Q09472	EP300	Q13315	ATM	S1038	Q1036K	1036	Missense	proximal	-2	no	11.552	11.281	EPSD	ICGC;COSMIC	9.540	Down-regulation
Atypical_PIKK_ATM_ATM_ST	Q09472	EP300	Q13315	ATM	S1220	D1218G	1218	Missense	proximal	-2	no	15.159	15.015	EPSD	ICGC;COSMIC	9.540	Down-regulation
Atypical_PIKK_ATM_ATM_ST	Q09472	EP300	Q13315	ATM	S1220	P1219H	1219	Missense	proximal	-1	no	15.159	15.247	EPSD	ICGC;COSMIC	9.540	Up-regulation
Atypical_PIKK_ATM_ATM_ST	Q09472	EP300	Q13315	ATM	S1220	P1222T	1222	Missense	proximal	2	no	15.159	15.352	EPSD	ICGC;COSMIC	9.540	Up-regulation
Atypical_PIKK_ATM_ATM_ST	Q09472	EP300	Q13315	ATM	T1724	D1729N	1729	Missense	distal	5	no	13.479	13.367	EPSD	ICGC;COSMIC	9.540	Down-regulation
Atypical_PIKK_ATM_ATM_ST	Q09472	EP300	Q13315	ATM	S2366	P2367Q	2367	Missense	proximal	1	no	8.463	13.265	EPSD	ICGC;COSMIC	9.540	Gain
Atypical_PIKK_ATM_ATM_ST	Q13263	TRIM28	Q13315	ATM	S50	G54A	54	Missense	distal	4	no	10.566	10.090	EPSD	ICGC	9.540	Down-regulation
Atypical_PIKK_ATM_ATM_ST	Q13263	TRIM28	Q13315	ATM	S50	A44T	44	Missense	distal	-6	no	10.566	10.517	EPSD	ICGC	9.540	Down-regulation
Atypical_PIKK_ATM_ATM_ST	Q13263	TRIM28	Q13315	ATM	S460	P463S	463	Missense	distal	3	no	10.071	9.920	EPSD	ICGC;COSMIC	9.540	Down-regulation
Atypical_PIKK_ATM_ATM_ST	Q13263	TRIM28	Q13315	ATM	S501	P503A	503	Missense	proximal	2	no	14.167	14.039	EPSD	ICGC;COSMIC	9.540	Down-regulation
Atypical_PIKK_ATM_ATM_ST	Q13263	TRIM28	Q13315	ATM	S594	S598N	598	Missense	distal	4	no	10.834	10.962	EPSD	ICGC;GDSC;CCLE	9.540	Up-regulation
Atypical_PIKK_ATM_ATM_ST	Q13263	TRIM28	Q13315	ATM	S757	Y755N	755	Missense	proximal	-2	no	9.585	9.575	EPSD	ICGC	9.540	Down-regulation
Atypical_PIKK_ATM_ATM_ST	Q13263	TRIM28	Q13315	ATM	S824	G821V	821	Missense	distal	-3	no	15.344	15.484	PhosphoSitePlus	ICGC	9.540	Up-regulation
Atypical_PIKK_ATM_ATM_ST	Q13263	TRIM28	Q13315	ATM	S824	G830S	830	Missense	distal	6	no	15.344	15.363	PhosphoSitePlus	ICGC;COSMIC	9.540	Up-regulation
Atypical_PIKK_ATM_ATM_ST	Q13263	TRIM28	Q13315	ATM	S828	G821V	821	Missense	distal	-7	no	9.840	9.872	EPSD	ICGC	9.540	Up-regulation
Atypical_PIKK_ATM_ATM_ST	Q13263	TRIM28	Q13315	ATM	S828	G834V	834	Missense	distal	6	no	9.840	9.835	EPSD	ICGC	9.540	Down-regulation
Atypical_PIKK_ATM_ATM_ST	Q13263	TRIM28	Q13315	ATM	S828	G830S	830	Missense	proximal	2	no	9.840	10.698	EPSD	ICGC;COSMIC	9.540	Up-regulation
Atypical_PIKK_ATM_ATM_ST	Q13263	TRIM28	Q13315	ATM	S828	D833V	833	Missense	distal	5	no	9.840	9.966	EPSD	ICGC;COSMIC	9.540	Up-regulation
Atypical_PIKK_ATM_ATM_ST	Q15910	EZH2	Q13315	ATM	S647	Y641F	641	Missense	distal	-6	no	18.239	17.957	EPSD	ICGC;COSMIC	9.540	Down-regulation
Atypical_PIKK_ATM_ATM_ST	Q15910	EZH2	Q13315	ATM	S647	Y641H	641	Missense	distal	-6	no	18.239	18.309	EPSD	ICGC;COSMIC	9.540	Up-regulation
Atypical_PIKK_ATM_ATM_ST	Q15910	EZH2	Q13315	ATM	S647	D652H	652	Missense	distal	5	no	18.239	18.292	EPSD	ICGC;COSMIC	9.540	Up-regulation
Atypical_PIKK_ATM_ATM_ST	Q15910	EZH2	Q13315	ATM	S647	Y641N	641	Missense	distal	-6	no	18.239	18.373	EPSD	ICGC;COSMIC	9.540	Up-regulation
Atypical_PIKK_ATM_ATM_ST	Q15910	EZH2	Q13315	ATM	S647	Y641S	641	Missense	distal	-6	no	18.239	18.488	EPSD	ICGC;COSMIC	9.540	Up-regulation
Atypical_PIKK_ATM_ATM_ST	Q15910	EZH2	Q13315	ATM	S647	Y641C	641	Missense	distal	-6	no	18.239	18.108	EPSD	ICGC;COSMIC;CCLE	9.540	Down-regulation
Atypical_PIKK_ATM_ATM_ST	Q15910	EZH2	Q13315	ATM	S647	R653I	653	Missense	distal	6	no	18.239	18.216	EPSD	ICGC;COSMIC	9.540	Down-regulation
Atypical_PIKK_ATM_ATM_ST	Q15910	EZH2	Q13315	ATM	S647	C642R	642	Missense	distal	-5	no	18.239	18.222	EPSD	ICGC;COSMIC	9.540	Down-regulation
Atypical_PIKK_ATM_ATM_ST	O15151	MDM4	Q13315	ATM	S20	S20F	20	Missense	central	0	yes	11.562	0.000	EPSD	ICGC;COSMIC	9.540	Loss
Atypical_PIKK_ATM_ATM_ST	O15151	MDM4	Q13315	ATM	S264	G268W	268	Missense	distal	4	no	12.206	12.403	EPSD	ICGC;COSMIC	9.540	Up-regulation
Atypical_PIKK_ATM_ATM_ST	O15151	MDM4	Q13315	ATM	S264	A257D	257	Missense	distal	-7	no	12.206	12.080	EPSD	ICGC;COSMIC	9.540	Down-regulation
Atypical_PIKK_ATM_ATM_ST	O15151	MDM4	Q13315	ATM	S344	I349T	349	Missense	distal	5	no	10.085	9.859	EPSD	ICGC;COSMIC	9.540	Down-regulation
Atypical_PIKK_ATM_ATM_ST	Q9H9Q4	NHEJ1	Q13315	ATM	S55	D50E	50	Missense	distal	-5	no	12.475	12.520	EPSD	ICGC	9.540	Up-regulation
Atypical_PIKK_ATM_ATM_ST	Q9H9Q4	NHEJ1	Q13315	ATM	S55	Q48H	48	Missense	distal	-7	no	12.475	12.360	EPSD	ICGC;COSMIC	9.540	Down-regulation
Atypical_PIKK_ATM_ATM_ST	Q9H9Q4	NHEJ1	Q13315	ATM	S132	P138L	138	Missense	distal	6	no	15.143	15.097	EPSD	ICGC	9.540	Down-regulation
Atypical_PIKK_ATM_ATM_ST	Q9H9Q4	NHEJ1	Q13315	ATM	S132	R137S	137	Missense	distal	5	no	15.143	14.977	EPSD	ICGC;COSMIC	9.540	Down-regulation
Atypical_PIKK_ATM_ATM_ST	Q9H9Q4	NHEJ1	Q13315	ATM	S132	R137H	137	Missense	distal	5	no	15.143	15.117	EPSD	ICGC;COSMIC	9.540	Down-regulation
Atypical_PIKK_ATM_ATM_ST	Q9H9Q4	NHEJ1	Q13315	ATM	S132	Q133K	133	Missense	proximal	1	no	15.143	8.294	EPSD	ICGC;COSMIC	9.540	Loss
Atypical_PIKK_ATM_ATM_ST	Q9H9Q4	NHEJ1	Q13315	ATM	T223	Q230K	230	Missense	distal	7	no	10.358	10.370	EPSD	ICGC	9.540	Up-regulation
Atypical_PIKK_ATM_ATM_ST	Q9H9Q4	NHEJ1	Q13315	ATM	S245	H239Y	239	Missense	distal	-6	no	10.670	10.600	EPSD	ICGC;COSMIC	9.540	Down-regulation
Atypical_PIKK_ATM_ATM_ST	Q9H9Q4	NHEJ1	Q13315	ATM	S245	Q247K	247	Missense	proximal	2	no	10.670	10.152	EPSD	ICGC	9.540	Down-regulation
Atypical_PIKK_ATM_ATM_ST	Q9H9Q4	NHEJ1	Q13315	ATM	S245	D250N	250	Missense	distal	5	no	10.670	10.558	EPSD	ICGC;GDSC;CCLE	9.540	Down-regulation
Atypical_PIKK_ATM_ATM_ST	Q9H9Q4	NHEJ1	Q13315	ATM	S251	Q247K	247	Missense	distal	-4	no	13.629	13.381	PhosphoSitePlus	ICGC	9.540	Down-regulation
Atypical_PIKK_ATM_ATM_ST	Q9H9Q4	NHEJ1	Q13315	ATM	S251	D250N	250	Missense	proximal	-1	no	13.629	13.628	PhosphoSitePlus	ICGC;GDSC;CCLE	9.540	Down-regulation
Atypical_PIKK_ATM_ATM_ST	Q14191	WRN	Q13315	ATM	S248	M250R	250	Missense	proximal	2	no	9.686	9.746	EPSD	ICGC;COSMIC	9.540	Up-regulation
Atypical_PIKK_ATM_ATM_ST	Q14191	WRN	Q13315	ATM	S248	E244K	244	Missense	distal	-4	no	9.686	8.714	EPSD	ICGC	9.540	Loss
Atypical_PIKK_ATM_ATM_ST	Q14191	WRN	Q13315	ATM	S409	Q407P	407	Missense	proximal	-2	no	15.058	14.945	EPSD	ICGC	9.540	Down-regulation
Atypical_PIKK_ATM_ATM_ST	Q14191	WRN	Q13315	ATM	S440	E445D	445	Missense	distal	5	no	10.013	10.270	EPSD	ICGC;COSMIC	9.540	Up-regulation
Atypical_PIKK_ATM_ATM_ST	Q14191	WRN	Q13315	ATM	S440	D441Y	441	Missense	proximal	1	no	10.013	10.328	EPSD	ICGC	9.540	Up-regulation
Atypical_PIKK_ATM_ATM_ST	Q14191	WRN	Q13315	ATM	S453	D460N	460	Missense	distal	7	no	9.647	9.653	EPSD	ICGC;COSMIC	9.540	Up-regulation
Atypical_PIKK_ATM_ATM_ST	Q14191	WRN	Q13315	ATM	S453	D460Y	460	Missense	distal	7	no	9.647	9.672	EPSD	ICGC;COSMIC	9.540	Up-regulation
Atypical_PIKK_ATM_ATM_ST	Q14191	WRN	Q13315	ATM	S453	N459I	459	Missense	distal	6	no	9.647	9.616	EPSD	ICGC;COSMIC	9.540	Down-regulation
Atypical_PIKK_ATM_ATM_ST	Q14191	WRN	Q13315	ATM	S462	N459I	459	Missense	distal	-3	no	8.928	9.624	EPSD	ICGC;COSMIC	9.540	Gain
Atypical_PIKK_ATM_ATM_ST	Q14191	WRN	Q13315	ATM	S478	E472D	472	Missense	distal	-6	no	10.713	10.498	EPSD	ICGC;COSMIC	9.540	Down-regulation
Atypical_PIKK_ATM_ATM_ST	Q14191	WRN	Q13315	ATM	S1058	L1061I	1061	Missense	distal	3	no	15.586	15.806	EPSD	ICGC;COSMIC	9.540	Up-regulation
Atypical_PIKK_ATM_ATM_ST	Q14191	WRN	Q13315	ATM	S1378	C1374F	1374	Missense	distal	-4	no	10.599	10.773	EPSD	ICGC;COSMIC	9.540	Up-regulation
Atypical_PIKK_ATM_ATM_ST	Q13362	PPP2R5C	Q13315	ATM	S337	K333T	333	Missense	distal	-4	no	9.408	9.718	EPSD	ICGC;COSMIC	9.540	Gain
Atypical_PIKK_ATM_ATM_ST	Q13362	PPP2R5C	Q13315	ATM	S360	E353Q	353	Missense	distal	-7	no	9.988	9.433	EPSD	ICGC;COSMIC	9.540	Loss
Atypical_PIKK_ATM_ATM_ST	Q13362	PPP2R5C	Q13315	ATM	S360	L358F	358	Missense	proximal	-2	no	9.988	9.477	EPSD	ICGC;COSMIC	9.540	Loss
Atypical_PIKK_ATM_ATM_ST	Q13362	PPP2R5C	Q13315	ATM	S360	A364V	364	Missense	distal	4	no	9.988	10.641	EPSD	ICGC;COSMIC	9.540	Up-regulation
Atypical_PIKK_ATM_ATM_ST	Q14674	ESPL1	Q13315	ATM	S244	L242F	242	Missense	proximal	-2	no	10.020	9.509	EPSD	ICGC	9.540	Loss
Atypical_PIKK_ATM_ATM_ST	Q14674	ESPL1	Q13315	ATM	S244	A248T	248	Missense	distal	4	no	10.020	10.455	EPSD	ICGC;COSMIC	9.540	Up-regulation
Atypical_PIKK_ATM_ATM_ST	Q14674	ESPL1	Q13315	ATM	S244	L243I	243	Missense	proximal	-1	no	10.020	9.934	EPSD	ICGC;COSMIC	9.540	Down-regulation
Atypical_PIKK_ATM_ATM_ST	Q14674	ESPL1	Q13315	ATM	S244	R247K	247	Missense	distal	3	no	10.020	9.948	EPSD	ICGC;COSMIC	9.540	Down-regulation
Atypical_PIKK_ATM_ATM_ST	Q14674	ESPL1	Q13315	ATM	S810	S816P	816	Missense	distal	6	no	9.715	9.704	EPSD	ICGC;COSMIC;GDSC	9.540	Down-regulation
Atypical_PIKK_ATM_ATM_ST	Q14674	ESPL1	Q13315	ATM	S810	K807E	807	Missense	distal	-3	no	9.715	9.648	EPSD	ICGC;COSMIC	9.540	Down-regulation
Atypical_PIKK_ATM_ATM_ST	Q14674	ESPL1	Q13315	ATM	S1406	D1403G	1403	Missense	distal	-3	no	9.671	9.704	EPSD	ICGC;COSMIC	9.540	Up-regulation
Atypical_PIKK_ATM_ATM_ST	Q14674	ESPL1	Q13315	ATM	S1406	E1402D	1402	Missense	distal	-4	no	9.671	9.389	EPSD	ICGC	9.540	Loss
Atypical_PIKK_ATM_ATM_ST	Q14674	ESPL1	Q13315	ATM	S1406	A1409T	1409	Missense	distal	3	no	9.671	9.696	EPSD	ICGC;COSMIC	9.540	Up-regulation
Atypical_PIKK_ATM_ATM_ST	Q14674	ESPL1	Q13315	ATM	S1406	L1411Q	1411	Missense	distal	5	no	9.671	9.560	EPSD	ICGC;COSMIC	9.540	Down-regulation
Atypical_PIKK_ATM_ATM_ST	Q14674	ESPL1	Q13315	ATM	S1455	R1456Q	1456	Missense	proximal	1	no	7.050	13.701	EPSD	ICGC;COSMIC;CCLE	9.540	Gain
Atypical_PIKK_ATM_ATM_ST	Q14674	ESPL1	Q13315	ATM	S1539	R1535S	1535	Missense	distal	-4	no	8.883	9.693	EPSD	ICGC	9.540	Gain
Atypical_PIKK_ATM_ATM_ST	Q9UER7	DAXX	Q13315	ATM	S176	R182S	182	Missense	distal	6	no	14.524	14.542	EPSD	ICGC;COSMIC	9.540	Up-regulation
Atypical_PIKK_ATM_ATM_ST	Q9UER7	DAXX	Q13315	ATM	S176	G183V	183	Missense	distal	7	no	14.524	14.531	EPSD	ICGC;COSMIC	9.540	Up-regulation
Atypical_PIKK_ATM_ATM_ST	Q9UER7	DAXX	Q13315	ATM	S424	E417G	417	Missense	distal	-7	no	15.255	14.387	EPSD	ICGC	9.540	Down-regulation
Atypical_PIKK_ATM_ATM_ST	Q9UER7	DAXX	Q13315	ATM	S564	S561N	561	Missense	distal	-3	no	13.924	13.897	PhosphoSitePlus	ICGC;COSMIC	9.540	Down-regulation
Atypical_PIKK_ATM_ATM_ST	Q9UER7	DAXX	Q13315	ATM	S618	V617F	617	Missense	proximal	-1	no	9.733	9.730	EPSD	ICGC;COSMIC	9.540	Down-regulation
Atypical_PIKK_ATM_ATM_ST	Q9UER7	DAXX	Q13315	ATM	S618	V617I	617	Missense	proximal	-1	no	9.733	9.935	EPSD	ICGC;COSMIC	9.540	Up-regulation
Atypical_PIKK_ATM_ATM_ST	Q9UER7	DAXX	Q13315	ATM	S675	P678L	678	Missense	distal	3	no	11.103	11.234	EPSD	ICGC	9.540	Up-regulation
Atypical_PIKK_ATM_ATM_ST	Q9UER7	DAXX	Q13315	ATM	S675	P670H	670	Missense	distal	-5	no	11.103	11.148	EPSD	ICGC;COSMIC	9.540	Up-regulation
Atypical_PIKK_ATM_ATM_ST	Q9UER7	DAXX	Q13315	ATM	S675	S671P	671	Missense	distal	-4	no	11.103	10.434	EPSD	ICGC;COSMIC;GDSC;CCLE	9.540	Down-regulation
Atypical_PIKK_ATM_ATM_ST	Q9UER7	DAXX	Q13315	ATM	S688	T684M	684	Missense	distal	-4	no	9.994	9.369	EPSD	ICGC;COSMIC	9.540	Loss
Atypical_PIKK_ATM_ATM_ST	Q9UER7	DAXX	Q13315	ATM	S737	D738Y	738	Missense	proximal	1	no	10.480	10.795	EPSD	ICGC	9.540	Up-regulation
Atypical_PIKK_ATM_ATM_ST	Q9UER7	DAXX	Q13315	ATM	S739	D738Y	738	Missense	proximal	-1	no	10.772	10.777	EPSD	ICGC	9.540	Up-regulation
Atypical_PIKK_ATM_ATM_ST	Q5UIP0	RIF1	Q13315	ATM	S111	S111P	111	Missense	central	0	yes	9.942	0.000	EPSD	ICGC;COSMIC	9.540	Loss
Atypical_PIKK_ATM_ATM_ST	Q5UIP0	RIF1	Q13315	ATM	S143	V137L	137	Missense	distal	-6	no	9.576	9.544	EPSD	ICGC;COSMIC	9.540	Down-regulation
Atypical_PIKK_ATM_ATM_ST	Q5UIP0	RIF1	Q13315	ATM	S143	E145D	145	Missense	proximal	2	no	9.576	9.445	EPSD	ICGC;COSMIC	9.540	Loss
Atypical_PIKK_ATM_ATM_ST	Q5UIP0	RIF1	Q13315	ATM	S402	A400S	400	Missense	proximal	-2	no	9.586	9.774	EPSD	ICGC	9.540	Up-regulation
Atypical_PIKK_ATM_ATM_ST	Q5UIP0	RIF1	Q13315	ATM	S402	P403L	403	Missense	proximal	1	no	9.586	8.031	EPSD	ICGC;COSMIC;GDSC	9.540	Loss
Atypical_PIKK_ATM_ATM_ST	Q5UIP0	RIF1	Q13315	ATM	S402	P407R	407	Missense	distal	5	no	9.586	9.570	EPSD	ICGC;COSMIC	9.540	Down-regulation
Atypical_PIKK_ATM_ATM_ST	Q5UIP0	RIF1	Q13315	ATM	S989	D984Y	984	Missense	distal	-5	no	16.596	16.831	EPSD	ICGC	9.540	Up-regulation
Atypical_PIKK_ATM_ATM_ST	Q5UIP0	RIF1	Q13315	ATM	S1089	N1085I	1085	Missense	distal	-4	no	14.947	15.164	EPSD	ICGC	9.540	Up-regulation
Atypical_PIKK_ATM_ATM_ST	Q5UIP0	RIF1	Q13315	ATM	S1162	G1156V	1156	Missense	distal	-6	no	11.945	11.890	EPSD	ICGC;COSMIC	9.540	Down-regulation
Atypical_PIKK_ATM_ATM_ST	Q5UIP0	RIF1	Q13315	ATM	S1162	C1155F	1155	Missense	distal	-7	no	11.945	11.789	EPSD	ICGC	9.540	Down-regulation
Atypical_PIKK_ATM_ATM_ST	Q5UIP0	RIF1	Q13315	ATM	S1236	S1238F	1238	Missense	proximal	2	no	11.274	9.796	EPSD	ICGC;COSMIC	9.540	Down-regulation
Atypical_PIKK_ATM_ATM_ST	Q5UIP0	RIF1	Q13315	ATM	S1236	R1233I	1233	Missense	distal	-3	no	11.274	11.204	EPSD	ICGC	9.540	Down-regulation
Atypical_PIKK_ATM_ATM_ST	Q5UIP0	RIF1	Q13315	ATM	S1236	P1239L	1239	Missense	distal	3	no	11.274	11.405	EPSD	ICGC	9.540	Up-regulation
Atypical_PIKK_ATM_ATM_ST	Q5UIP0	RIF1	Q13315	ATM	S1238	S1238F	1238	Missense	central	0	yes	11.402	0.000	EPSD	ICGC;COSMIC	9.540	Loss
Atypical_PIKK_ATM_ATM_ST	Q5UIP0	RIF1	Q13315	ATM	S1238	R1233I	1233	Missense	distal	-5	no	11.402	11.441	EPSD	ICGC	9.540	Up-regulation
Atypical_PIKK_ATM_ATM_ST	Q5UIP0	RIF1	Q13315	ATM	S1238	P1239L	1239	Missense	proximal	1	no	11.402	9.847	EPSD	ICGC	9.540	Down-regulation
Atypical_PIKK_ATM_ATM_ST	Q5UIP0	RIF1	Q13315	ATM	S1384	K1385Q	1385	Missense	proximal	1	no	6.655	13.504	EPSD	ICGC;COSMIC	9.540	Gain
Atypical_PIKK_ATM_ATM_ST	Q5UIP0	RIF1	Q13315	ATM	S1431	D1433H	1433	Missense	proximal	2	no	13.958	12.896	EPSD	ICGC;COSMIC	9.540	Down-regulation
Atypical_PIKK_ATM_ATM_ST	Q5UIP0	RIF1	Q13315	ATM	T1518	I1511T	1511	Missense	distal	-7	no	14.892	15.475	EPSD	ICGC;COSMIC	9.540	Up-regulation
Atypical_PIKK_ATM_ATM_ST	Q5UIP0	RIF1	Q13315	ATM	T1518	D1523Y	1523	Missense	distal	5	no	14.892	14.870	EPSD	ICGC	9.540	Down-regulation
Atypical_PIKK_ATM_ATM_ST	Q5UIP0	RIF1	Q13315	ATM	S1542	Q1537P	1537	Missense	distal	-5	no	13.468	13.605	EPSD	ICGC	9.540	Up-regulation
Atypical_PIKK_ATM_ATM_ST	Q5UIP0	RIF1	Q13315	ATM	S1554	S1552A	1552	Missense	proximal	-2	no	9.723	9.536	EPSD	ICGC;COSMIC	9.540	Loss
Atypical_PIKK_ATM_ATM_ST	Q5UIP0	RIF1	Q13315	ATM	S1554	A1559S	1559	Missense	distal	5	no	9.723	9.675	EPSD	ICGC;COSMIC	9.540	Down-regulation
Atypical_PIKK_ATM_ATM_ST	Q5UIP0	RIF1	Q13315	ATM	S1554	K1560E	1560	Missense	distal	6	no	9.723	9.769	EPSD	ICGC;COSMIC	9.540	Up-regulation
Atypical_PIKK_ATM_ATM_ST	Q5UIP0	RIF1	Q13315	ATM	S1554	A1559T	1559	Missense	distal	5	no	9.723	9.659	EPSD	ICGC;COSMIC	9.540	Down-regulation
Atypical_PIKK_ATM_ATM_ST	Q5UIP0	RIF1	Q13315	ATM	S1554	E1553A	1553	Missense	proximal	-1	no	9.723	9.352	EPSD	ICGC;COSMIC	9.540	Loss
Atypical_PIKK_ATM_ATM_ST	Q5UIP0	RIF1	Q13315	ATM	S1616	P1617Q	1617	Missense	proximal	1	no	9.500	14.302	EPSD	ICGC;COSMIC	9.540	Gain
Atypical_PIKK_ATM_ATM_ST	Q5UIP0	RIF1	Q13315	ATM	S1760	K1763Q	1763	Missense	distal	3	no	11.194	11.164	EPSD	ICGC	9.540	Down-regulation
Atypical_PIKK_ATM_ATM_ST	Q5UIP0	RIF1	Q13315	ATM	S1760	K1764E	1764	Missense	distal	4	no	11.194	10.816	EPSD	ICGC;COSMIC	9.540	Down-regulation
Atypical_PIKK_ATM_ATM_ST	Q5UIP0	RIF1	Q13315	ATM	S1760	D1756G	1756	Missense	distal	-4	no	11.194	10.410	EPSD	ICGC;COSMIC	9.540	Down-regulation
Atypical_PIKK_ATM_ATM_ST	Q5UIP0	RIF1	Q13315	ATM	T1762	K1763Q	1763	Missense	proximal	1	no	7.066	13.914	EPSD	ICGC	9.540	Gain
Atypical_PIKK_ATM_ATM_ST	Q5UIP0	RIF1	Q13315	ATM	S1772	P1773L	1773	Missense	proximal	1	no	9.763	8.208	EPSD	ICGC;COSMIC	9.540	Loss
Atypical_PIKK_ATM_ATM_ST	Q5UIP0	RIF1	Q13315	ATM	S1772	P1770T	1770	Missense	proximal	-2	no	9.763	9.912	EPSD	ICGC;COSMIC	9.540	Up-regulation
Atypical_PIKK_ATM_ATM_ST	Q5UIP0	RIF1	Q13315	ATM	S1774	P1773L	1773	Missense	proximal	-1	no	9.863	10.020	EPSD	ICGC;COSMIC	9.540	Up-regulation
Atypical_PIKK_ATM_ATM_ST	Q5UIP0	RIF1	Q13315	ATM	S1774	P1770T	1770	Missense	distal	-4	no	9.863	10.149	EPSD	ICGC;COSMIC	9.540	Up-regulation
Atypical_PIKK_ATM_ATM_ST	Q5UIP0	RIF1	Q13315	ATM	S1777	P1773L	1773	Missense	distal	-4	no	14.969	14.699	EPSD	ICGC;COSMIC	9.540	Down-regulation
Atypical_PIKK_ATM_ATM_ST	Q5UIP0	RIF1	Q13315	ATM	S1777	P1770T	1770	Missense	distal	-7	no	14.969	15.124	EPSD	ICGC;COSMIC	9.540	Up-regulation
Atypical_PIKK_ATM_ATM_ST	Q5UIP0	RIF1	Q13315	ATM	S1854	T1861A	1861	Missense	distal	7	no	11.330	11.344	EPSD	ICGC;COSMIC	9.540	Up-regulation
Atypical_PIKK_ATM_ATM_ST	Q5UIP0	RIF1	Q13315	ATM	S2011	T2016A	2016	Missense	distal	5	no	9.802	9.866	EPSD	ICGC	9.540	Up-regulation
Atypical_PIKK_ATM_ATM_ST	Q5UIP0	RIF1	Q13315	ATM	S2117	E2112K	2112	Missense	distal	-5	no	13.286	13.368	EPSD	ICGC;COSMIC	9.540	Up-regulation
Atypical_PIKK_ATM_ATM_ST	Q5UIP0	RIF1	Q13315	ATM	S2117	H2115N	2115	Missense	proximal	-2	no	13.286	13.534	EPSD	ICGC;COSMIC	9.540	Up-regulation
Atypical_PIKK_ATM_ATM_ST	Q5UIP0	RIF1	Q13315	ATM	S2124	G2130V	2130	Missense	distal	6	no	14.155	14.150	EPSD	ICGC;COSMIC	9.540	Down-regulation
Atypical_PIKK_ATM_ATM_ST	Q5UIP0	RIF1	Q13315	ATM	S2129	G2130V	2130	Missense	proximal	1	no	11.021	4.500	EPSD	ICGC;COSMIC	9.540	Loss
Atypical_PIKK_ATM_ATM_ST	Q5UIP0	RIF1	Q13315	ATM	S2176	V2170A	2170	Missense	distal	-6	no	9.979	10.215	EPSD	ICGC;COSMIC	9.540	Up-regulation
Atypical_PIKK_ATM_ATM_ST	Q5UIP0	RIF1	Q13315	ATM	S2189	Q2190K	2190	Missense	proximal	1	no	13.821	6.973	EPSD	ICGC;COSMIC	9.540	Loss
Atypical_PIKK_ATM_ATM_ST	Q5UIP0	RIF1	Q13315	ATM	S2196	R2202H	2202	Missense	distal	6	no	10.128	10.113	EPSD	ICGC;COSMIC	9.540	Down-regulation
Atypical_PIKK_ATM_ATM_ST	Q5UIP0	RIF1	Q13315	ATM	S2196	N2199H	2199	Missense	distal	3	no	10.128	10.151	EPSD	ICGC;COSMIC	9.540	Up-regulation
Atypical_PIKK_ATM_ATM_ST	Q5UIP0	RIF1	Q13315	ATM	S2196	Q2190K	2190	Missense	distal	-6	no	10.128	10.052	EPSD	ICGC;COSMIC	9.540	Down-regulation
Atypical_PIKK_ATM_ATM_ST	Q5UIP0	RIF1	Q13315	ATM	S2243	I2236K	2236	Missense	distal	-7	no	10.397	10.749	EPSD	ICGC;COSMIC	9.540	Up-regulation
Atypical_PIKK_ATM_ATM_ST	Q5UIP0	RIF1	Q13315	ATM	S2243	I2236V	2236	Missense	distal	-7	no	10.397	10.581	EPSD	ICGC	9.540	Up-regulation
Atypical_PIKK_ATM_ATM_ST	Q5UIP0	RIF1	Q13315	ATM	S2260	G2262E	2262	Missense	proximal	2	no	10.283	11.653	EPSD	ICGC;COSMIC	9.540	Up-regulation
Atypical_PIKK_ATM_ATM_ST	Q5UIP0	RIF1	Q13315	ATM	S2260	R2264C	2264	Missense	distal	4	no	10.283	10.611	EPSD	ICGC	9.540	Up-regulation
Atypical_PIKK_ATM_ATM_ST	Q13541	EIF4EBP1	Q13315	ATM	S8	C7S	7	Missense	proximal	-1	no	13.961	14.161	EPSD	ICGC;COSMIC	9.540	Up-regulation
Atypical_PIKK_ATM_ATM_ST	Q13541	EIF4EBP1	Q13315	ATM	S94	S94I	94	Missense	central	0	yes	15.970	0.000	PhosphoSitePlus	ICGC	9.540	Loss
Atypical_PIKK_ATM_ATM_ST	Q13541	EIF4EBP1	Q13315	ATM	S94	H97Q	97	Missense	distal	3	no	15.970	15.830	PhosphoSitePlus	ICGC;COSMIC	9.540	Down-regulation
Atypical_PIKK_ATM_ATM_ST	Q13541	EIF4EBP1	Q13315	ATM	S94	S101C	101	Missense	distal	7	no	15.970	16.022	PhosphoSitePlus	ICGC;COSMIC	9.540	Up-regulation
Atypical_PIKK_ATM_ATM_ST	Q13541	EIF4EBP1	Q13315	ATM	S96	H97Q	97	Missense	proximal	1	no	-1.618	13.291	EPSD	ICGC;COSMIC	9.540	Gain
Atypical_PIKK_ATM_ATM_ST	Q13541	EIF4EBP1	Q13315	ATM	S101	S94I	94	Missense	distal	-7	no	12.020	11.355	EPSD	ICGC	9.540	Down-regulation
Atypical_PIKK_ATM_ATM_ST	Q13541	EIF4EBP1	Q13315	ATM	S101	R106Q	106	Missense	distal	5	no	12.020	11.908	EPSD	ICGC;COSMIC	9.540	Down-regulation
Atypical_PIKK_ATM_ATM_ST	Q13541	EIF4EBP1	Q13315	ATM	S101	G108C	108	Missense	distal	7	no	12.020	12.030	EPSD	ICGC;COSMIC	9.540	Up-regulation
Atypical_PIKK_ATM_ATM_ST	Q13541	EIF4EBP1	Q13315	ATM	S101	A107T	107	Missense	distal	6	no	12.020	12.003	EPSD	ICGC;COSMIC	9.540	Down-regulation
Atypical_PIKK_ATM_ATM_ST	Q13541	EIF4EBP1	Q13315	ATM	S101	D104Y	104	Missense	distal	3	no	12.020	12.078	EPSD	ICGC;COSMIC	9.540	Up-regulation
Atypical_PIKK_ATM_ATM_ST	Q13541	EIF4EBP1	Q13315	ATM	S101	H97Q	97	Missense	distal	-4	no	12.020	12.254	EPSD	ICGC;COSMIC	9.540	Up-regulation
Atypical_PIKK_ATM_ATM_ST	Q13541	EIF4EBP1	Q13315	ATM	S101	S101C	101	Missense	central	0	yes	12.020	0.000	EPSD	ICGC;COSMIC	9.540	Loss
Atypical_PIKK_ATM_ATM_ST	Q13541	EIF4EBP1	Q13315	ATM	S112	R106Q	106	Missense	distal	-6	no	15.382	15.526	EPSD	ICGC;COSMIC	9.540	Up-regulation
Atypical_PIKK_ATM_ATM_ST	Q13541	EIF4EBP1	Q13315	ATM	S112	G108C	108	Missense	distal	-4	no	15.382	14.598	EPSD	ICGC;COSMIC	9.540	Down-regulation
Atypical_PIKK_ATM_ATM_ST	Q13541	EIF4EBP1	Q13315	ATM	S112	E111D	111	Missense	proximal	-1	no	15.382	15.118	EPSD	ICGC	9.540	Down-regulation
Atypical_PIKK_ATM_ATM_ST	Q13541	EIF4EBP1	Q13315	ATM	S112	A107T	107	Missense	distal	-5	no	15.382	15.301	EPSD	ICGC;COSMIC	9.540	Down-regulation
Atypical_PIKK_ATM_ATM_ST	O15164	TRIM24	Q13315	ATM	S41	E34D	34	Missense	distal	-7	no	9.632	9.054	EPSD	ICGC;COSMIC	9.540	Loss
Atypical_PIKK_ATM_ATM_ST	O15164	TRIM24	Q13315	ATM	S41	A48V	48	Missense	distal	7	no	9.632	9.650	EPSD	ICGC	9.540	Up-regulation
Atypical_PIKK_ATM_ATM_ST	O15164	TRIM24	Q13315	ATM	S41	D40Y	40	Missense	proximal	-1	no	9.632	9.638	EPSD	ICGC;COSMIC	9.540	Up-regulation
Atypical_PIKK_ATM_ATM_ST	O15164	TRIM24	Q13315	ATM	S41	P39L	39	Missense	proximal	-2	no	9.632	9.479	EPSD	ICGC;COSMIC	9.540	Loss
Atypical_PIKK_ATM_ATM_ST	O15164	TRIM24	Q13315	ATM	S41	G44S	44	Missense	distal	3	no	9.632	9.502	EPSD	ICGC;COSMIC	9.540	Loss
Atypical_PIKK_ATM_ATM_ST	O15164	TRIM24	Q13315	ATM	T120	G123E	123	Missense	distal	3	no	12.553	12.247	EPSD	ICGC;COSMIC	9.540	Down-regulation
Atypical_PIKK_ATM_ATM_ST	O15164	TRIM24	Q13315	ATM	T120	I125T	125	Missense	distal	5	no	12.553	12.327	EPSD	ICGC;COSMIC	9.540	Down-regulation
Atypical_PIKK_ATM_ATM_ST	O15164	TRIM24	Q13315	ATM	S209	V208L	208	Missense	proximal	-1	no	11.788	12.076	EPSD	ICGC	9.540	Up-regulation
Atypical_PIKK_ATM_ATM_ST	O15164	TRIM24	Q13315	ATM	S209	A212S	212	Missense	distal	3	no	11.788	11.732	EPSD	ICGC	9.540	Down-regulation
Atypical_PIKK_ATM_ATM_ST	O15164	TRIM24	Q13315	ATM	S209	E207D	207	Missense	proximal	-2	no	11.788	11.309	EPSD	ICGC;COSMIC	9.540	Down-regulation
Atypical_PIKK_ATM_ATM_ST	O15164	TRIM24	Q13315	ATM	S209	G214C	214	Missense	distal	5	no	11.788	11.836	EPSD	ICGC;COSMIC	9.540	Up-regulation
Atypical_PIKK_ATM_ATM_ST	O15164	TRIM24	Q13315	ATM	S217	V221A	221	Missense	distal	4	no	14.219	13.566	EPSD	ICGC;COSMIC	9.540	Down-regulation
Atypical_PIKK_ATM_ATM_ST	O15164	TRIM24	Q13315	ATM	S217	A212S	212	Missense	distal	-5	no	14.219	14.226	EPSD	ICGC	9.540	Up-regulation
Atypical_PIKK_ATM_ATM_ST	O15164	TRIM24	Q13315	ATM	S217	G214C	214	Missense	distal	-3	no	14.219	14.108	EPSD	ICGC;COSMIC	9.540	Down-regulation
Atypical_PIKK_ATM_ATM_ST	O15164	TRIM24	Q13315	ATM	S445	S452L	452	Missense	distal	7	no	14.715	14.734	EPSD	ICGC	9.540	Up-regulation
Atypical_PIKK_ATM_ATM_ST	O15164	TRIM24	Q13315	ATM	S590	P591L	591	Missense	proximal	1	no	11.025	9.470	EPSD	ICGC;COSMIC	9.540	Loss
Atypical_PIKK_ATM_ATM_ST	O15164	TRIM24	Q13315	ATM	S590	P591S	591	Missense	proximal	1	no	11.025	4.049	EPSD	ICGC;COSMIC	9.540	Loss
Atypical_PIKK_ATM_ATM_ST	Q92630	DYRK2	Q13315	ATM	S30	P31Q	31	Missense	proximal	1	no	8.670	13.472	EPSD	ICGC;COSMIC	9.540	Gain
Atypical_PIKK_ATM_ATM_ST	Q92630	DYRK2	Q13315	ATM	T106	G110W	110	Missense	distal	4	no	14.045	14.242	PhosphoSitePlus;EPSD	ICGC	9.540	Up-regulation
Atypical_PIKK_ATM_ATM_ST	Q92630	DYRK2	Q13315	ATM	T106	R101Q	101	Missense	distal	-5	no	14.045	13.836	PhosphoSitePlus;EPSD	ICGC;COSMIC	9.540	Down-regulation
Atypical_PIKK_ATM_ATM_ST	Q9NY61	AATF	Q13315	ATM	S143	P147L	147	Missense	distal	4	no	9.847	10.066	EPSD	ICGC	9.540	Up-regulation
Atypical_PIKK_ATM_ATM_ST	Q9NY61	AATF	Q13315	ATM	S143	K138E	138	Missense	distal	-5	no	9.847	9.765	EPSD	ICGC	9.540	Down-regulation
Atypical_PIKK_ATM_ATM_ST	Q9NY61	AATF	Q13315	ATM	S189	A186S	186	Missense	distal	-3	no	15.955	16.400	PhosphoSitePlus	ICGC	9.540	Up-regulation
Atypical_PIKK_ATM_ATM_ST	Q9NY61	AATF	Q13315	ATM	S203	D200Y	200	Missense	distal	-3	no	10.110	9.997	EPSD	ICGC	9.540	Down-regulation
Atypical_PIKK_ATM_ATM_ST	Q9NY61	AATF	Q13315	ATM	S316	S320Y	320	Missense	distal	4	no	10.239	10.542	EPSD	ICGC	9.540	Up-regulation
Atypical_PIKK_ATM_ATM_ST	Q9NY61	AATF	Q13315	ATM	T410	R414C	414	Missense	distal	4	no	11.972	12.300	EPSD	ICGC	9.540	Up-regulation
Atypical_PIKK_ATM_ATM_ST	P51532	SMARCA4	Q13315	ATM	S17	P18Q	18	Missense	proximal	1	no	8.616	13.418	EPSD	ICGC;COSMIC	9.540	Gain
Atypical_PIKK_ATM_ATM_ST	P51532	SMARCA4	Q13315	ATM	S23	G19S	19	Missense	distal	-4	no	9.132	9.920	EPSD	ICGC	9.540	Gain
Atypical_PIKK_ATM_ATM_ST	P51532	SMARCA4	Q13315	ATM	S117	S111N	111	Missense	distal	-6	no	13.976	13.861	EPSD	ICGC	9.540	Down-regulation
Atypical_PIKK_ATM_ATM_ST	P51532	SMARCA4	Q13315	ATM	S117	M113I	113	Missense	distal	-4	no	13.976	14.272	EPSD	ICGC;COSMIC	9.540	Up-regulation
Atypical_PIKK_ATM_ATM_ST	P51532	SMARCA4	Q13315	ATM	S117	H116Y	116	Missense	proximal	-1	no	13.976	14.132	EPSD	ICGC;COSMIC	9.540	Up-regulation
Atypical_PIKK_ATM_ATM_ST	P51532	SMARCA4	Q13315	ATM	S323	V318F	318	Missense	distal	-5	no	10.178	10.388	EPSD	ICGC	9.540	Up-regulation
Atypical_PIKK_ATM_ATM_ST	P51532	SMARCA4	Q13315	ATM	S323	P316H	316	Missense	distal	-7	no	10.178	10.101	EPSD	ICGC;COSMIC	9.540	Down-regulation
Atypical_PIKK_ATM_ATM_ST	P51532	SMARCA4	Q13315	ATM	S610	D607Y	607	Missense	distal	-3	no	13.887	13.773	EPSD	ICGC;COSMIC	9.540	Down-regulation
Atypical_PIKK_ATM_ATM_ST	P51532	SMARCA4	Q13315	ATM	S657	E650Q	650	Missense	distal	-7	no	10.774	10.219	EPSD	ICGC;COSMIC	9.540	Down-regulation
Atypical_PIKK_ATM_ATM_ST	P51532	SMARCA4	Q13315	ATM	S657	G661D	661	Missense	distal	4	no	10.774	10.852	EPSD	ICGC	9.540	Up-regulation
Atypical_PIKK_ATM_ATM_ST	P51532	SMARCA4	Q13315	ATM	S662	G661D	661	Missense	proximal	-1	no	9.942	10.080	EPSD	ICGC	9.540	Up-regulation
Atypical_PIKK_ATM_ATM_ST	P51532	SMARCA4	Q13315	ATM	S662	E669D	669	Missense	distal	7	no	9.942	9.955	EPSD	ICGC;COSMIC	9.540	Up-regulation
Atypical_PIKK_ATM_ATM_ST	P51532	SMARCA4	Q13315	ATM	S721	R726H	726	Missense	distal	5	no	15.380	15.355	PhosphoSitePlus	ICGC;GDSC;CCLE	9.540	Down-regulation
Atypical_PIKK_ATM_ATM_ST	P51532	SMARCA4	Q13315	ATM	S721	A725E	725	Missense	distal	4	no	15.380	15.430	PhosphoSitePlus	ICGC;COSMIC	9.540	Up-regulation
Atypical_PIKK_ATM_ATM_ST	P51532	SMARCA4	Q13315	ATM	S721	D716N	716	Missense	distal	-5	no	15.380	15.563	PhosphoSitePlus	ICGC;COSMIC	9.540	Up-regulation
Atypical_PIKK_ATM_ATM_ST	P51532	SMARCA4	Q13315	ATM	S721	V720L	720	Missense	proximal	-1	no	15.380	15.669	PhosphoSitePlus	ICGC	9.540	Up-regulation
Atypical_PIKK_ATM_ATM_ST	P51532	SMARCA4	Q13315	ATM	S746	L748P	748	Missense	proximal	2	no	8.926	9.715	EPSD	ICGC;COSMIC	9.540	Gain
Atypical_PIKK_ATM_ATM_ST	P51532	SMARCA4	Q13315	ATM	S833	V829L	829	Missense	distal	-4	no	10.726	10.776	EPSD	ICGC	9.540	Up-regulation
Atypical_PIKK_ATM_ATM_ST	P51532	SMARCA4	Q13315	ATM	T859	T858M	858	Missense	proximal	-1	no	10.761	10.460	EPSD	ICGC;COSMIC	9.540	Down-regulation
Atypical_PIKK_ATM_ATM_ST	P51532	SMARCA4	Q13315	ATM	S1240	H1241Q	1241	Missense	proximal	1	no	-0.822	14.087	EPSD	ICGC;COSMIC	9.540	Gain
Atypical_PIKK_ATM_ATM_ST	P51532	SMARCA4	Q13315	ATM	S1452	A1448V	1448	Missense	distal	-4	no	9.638	9.158	EPSD	ICGC;COSMIC	9.540	Loss
Atypical_PIKK_ATM_ATM_ST	P51532	SMARCA4	Q13315	ATM	S1452	P1453T	1453	Missense	proximal	1	no	9.638	4.631	EPSD	ICGC;COSMIC	9.540	Loss
Atypical_PIKK_ATM_ATM_ST	P51532	SMARCA4	Q13315	ATM	S1640	S1644N	1644	Missense	distal	4	no	10.738	10.865	EPSD	ICGC	9.540	Up-regulation
Atypical_PIKK_ATM_ATM_ST	P51532	SMARCA4	Q13315	ATM	S1642	S1644N	1644	Missense	proximal	2	no	9.642	9.000	EPSD	ICGC	9.540	Loss
Atypical_PIKK_ATM_ATM_ST	P51532	SMARCA4	Q13315	ATM	S1644	S1644N	1644	Missense	central	0	yes	13.851	0.000	EPSD	ICGC	9.540	Loss
Atypical_PIKK_ATM_ATM_ST	Q03111	MLLT1	Q13315	ATM	S209	S211R	211	Missense	proximal	2	no	9.721	8.723	EPSD	ICGC	9.540	Loss
Atypical_PIKK_ATM_ATM_ST	Q03111	MLLT1	Q13315	ATM	S209	R206G	206	Missense	distal	-3	no	9.721	9.259	EPSD	ICGC;COSMIC	9.540	Loss
Atypical_PIKK_ATM_ATM_ST	Q03111	MLLT1	Q13315	ATM	S209	S209F	209	Missense	central	0	yes	9.721	0.000	EPSD	ICGC	9.540	Loss
Atypical_PIKK_ATM_ATM_ST	Q03111	MLLT1	Q13315	ATM	S209	S214Y	214	Missense	distal	5	no	9.721	9.786	EPSD	ICGC;COSMIC	9.540	Up-regulation
Atypical_PIKK_ATM_ATM_ST	Q03111	MLLT1	Q13315	ATM	S308	R309Q	309	Missense	proximal	1	no	7.521	14.173	EPSD	ICGC;COSMIC	9.540	Gain
Atypical_PIKK_ATM_ATM_ST	Q03111	MLLT1	Q13315	ATM	S361	E362D	362	Missense	proximal	1	no	9.882	9.747	EPSD	ICGC	9.540	Down-regulation
Atypical_PIKK_ATM_ATM_ST	Q03111	MLLT1	Q13315	ATM	S361	A365S	365	Missense	distal	4	no	9.882	10.229	EPSD	ICGC;COSMIC	9.540	Up-regulation
Atypical_PIKK_ATM_ATM_ST	Q03111	MLLT1	Q13315	ATM	S375	P376T	376	Missense	proximal	1	no	10.488	5.481	EPSD	ICGC	9.540	Loss
Atypical_PIKK_ATM_ATM_ST	Q03111	MLLT1	Q13315	ATM	S387	D390E	390	Missense	distal	3	no	11.725	11.366	EPSD	ICGC	9.540	Down-regulation
Atypical_PIKK_ATM_ATM_ST	Q03111	MLLT1	Q13315	ATM	S394	H397N	397	Missense	distal	3	no	17.632	17.609	EPSD;PhosphoSitePlus	ICGC	9.540	Down-regulation
Atypical_PIKK_ATM_ATM_ST	Q03111	MLLT1	Q13315	ATM	S394	D390E	390	Missense	distal	-4	no	17.632	17.915	EPSD;PhosphoSitePlus	ICGC	9.540	Up-regulation
Atypical_PIKK_ATM_ATM_ST	Q03111	MLLT1	Q13315	ATM	S398	H397N	397	Missense	proximal	-1	no	15.392	15.541	PhosphoSitePlus;EPSD	ICGC	9.540	Up-regulation
Atypical_PIKK_ATM_ATM_ST	Q03111	MLLT1	Q13315	ATM	S398	R403S	403	Missense	distal	5	no	15.392	15.227	PhosphoSitePlus;EPSD	ICGC	9.540	Down-regulation
Atypical_PIKK_ATM_ATM_ST	Q03111	MLLT1	Q13315	ATM	S414	S421L	421	Missense	distal	7	no	10.442	10.461	EPSD	ICGC;COSMIC	9.540	Up-regulation
Atypical_PIKK_ATM_ATM_ST	Q03111	MLLT1	Q13315	ATM	S420	S421L	421	Missense	proximal	1	no	4.172	9.593	EPSD	ICGC;COSMIC	9.540	Gain
Atypical_PIKK_ATM_ATM_ST	Q03111	MLLT1	Q13315	ATM	S421	E423K	423	Missense	proximal	2	no	10.097	8.766	EPSD	ICGC;CCLE	9.540	Loss
Atypical_PIKK_ATM_ATM_ST	Q03111	MLLT1	Q13315	ATM	S421	S421L	421	Missense	central	0	yes	10.097	0.000	EPSD	ICGC;COSMIC	9.540	Loss
Atypical_PIKK_ATM_ATM_ST	Q03111	MLLT1	Q13315	ATM	S442	S435C	435	Missense	distal	-7	no	11.548	10.874	EPSD	ICGC	9.540	Down-regulation
Atypical_PIKK_ATM_ATM_ST	Q03111	MLLT1	Q13315	ATM	S442	S440R	440	Missense	proximal	-2	no	11.548	11.105	EPSD	ICGC	9.540	Down-regulation
Atypical_PIKK_ATM_ATM_ST	Q03111	MLLT1	Q13315	ATM	S454	P460T	460	Missense	distal	6	no	10.404	10.405	EPSD	ICGC;COSMIC	9.540	Up-regulation
Atypical_PIKK_ATM_ATM_ST	Q03111	MLLT1	Q13315	ATM	S454	S454R	454	Missense	central	0	yes	10.404	0.000	EPSD	ICGC	9.540	Loss
Atypical_PIKK_ATM_ATM_ST	Q03111	MLLT1	Q13315	ATM	S454	Q461P	461	Missense	distal	7	no	10.404	10.413	EPSD	ICGC;COSMIC	9.540	Up-regulation
Atypical_PIKK_ATM_ATM_ST	Q03111	MLLT1	Q13315	ATM	S454	S451P	451	Missense	distal	-3	no	10.404	10.600	EPSD	ICGC;COSMIC	9.540	Up-regulation
Atypical_PIKK_ATM_ATM_ST	Q03111	MLLT1	Q13315	ATM	S454	S454N	454	Missense	central	0	yes	10.404	0.000	EPSD	ICGC;COSMIC	9.540	Loss
Atypical_PIKK_ATM_ATM_ST	Q03111	MLLT1	Q13315	ATM	S475	S480G	480	Missense	distal	5	no	12.248	12.426	EPSD	ICGC;COSMIC	9.540	Up-regulation
Atypical_PIKK_ATM_ATM_ST	Q8IZL8	PELP1	Q13315	ATM	S25	A26E	26	Missense	proximal	1	no	8.791	9.767	EPSD	ICGC	9.540	Gain
Atypical_PIKK_ATM_ATM_ST	Q8IZL8	PELP1	Q13315	ATM	S251	S245F	245	Missense	distal	-6	no	12.382	11.850	EPSD	ICGC	9.540	Down-regulation
Atypical_PIKK_ATM_ATM_ST	O14757	CHEK1	Q13315	ATM	S284	V283L	283	Missense	proximal	-1	no	9.615	9.903	EPSD	ICGC	9.540	Up-regulation
Atypical_PIKK_ATM_ATM_ST	O14757	CHEK1	Q13315	ATM	S286	V283L	283	Missense	distal	-3	no	9.874	9.665	EPSD	ICGC	9.540	Down-regulation
Atypical_PIKK_ATM_ATM_ST	O14757	CHEK1	Q13315	ATM	S317	R322L	322	Missense	distal	5	no	16.627	16.626	EPSD	ICGC	9.540	Down-regulation
Atypical_PIKK_ATM_ATM_ST	O14757	CHEK1	Q13315	ATM	S331	L338S	338	Missense	distal	7	no	11.029	11.010	EPSD	ICGC;COSMIC	9.540	Down-regulation
Atypical_PIKK_ATM_ATM_ST	O14757	CHEK1	Q13315	ATM	S333	L338S	338	Missense	distal	5	no	11.340	11.176	EPSD	ICGC;COSMIC	9.540	Down-regulation
Atypical_PIKK_ATM_ATM_ST	O14757	CHEK1	Q13315	ATM	S345	L338S	338	Missense	distal	-7	no	13.959	14.547	PhosphoSitePlus	ICGC;COSMIC	9.540	Up-regulation
Atypical_PIKK_ATM_ATM_ST	O14757	CHEK1	Q13315	ATM	S357	G364V	364	Missense	distal	7	no	11.736	11.743	EPSD	ICGC;COSMIC	9.540	Up-regulation
Atypical_PIKK_ATM_ATM_ST	O14757	CHEK1	Q13315	ATM	S366	G364V	364	Missense	proximal	-2	no	14.062	13.840	EPSD	ICGC;COSMIC	9.540	Down-regulation
Atypical_PIKK_ATM_ATM_ST	O14757	CHEK1	Q13315	ATM	S468	I471V	471	Missense	distal	3	no	16.723	16.565	EPSD	ICGC	9.540	Down-regulation
Atypical_PIKK_ATM_ATM_ST	O14757	CHEK1	Q13315	ATM	S468	S468C	468	Missense	central	0	yes	16.723	0.000	EPSD	ICGC;COSMIC	9.540	Loss
Atypical_PIKK_ATM_ATM_ST	Q8IUQ4	SIAH1	Q13315	ATM	S19	P18L	18	Missense	proximal	-1	no	14.359	14.516	PhosphoSitePlus	ICGC;COSMIC	9.540	Up-regulation
Atypical_PIKK_ATM_ATM_ST	Q8IUQ4	SIAH1	Q13315	ATM	S19	C16Y	16	Missense	distal	-3	no	14.359	14.324	PhosphoSitePlus	ICGC	9.540	Down-regulation
Atypical_PIKK_ATM_ATM_ST	Q8IUQ4	SIAH1	Q13315	ATM	S19	P23T	23	Missense	distal	4	no	14.359	14.325	PhosphoSitePlus	ICGC	9.540	Down-regulation
Atypical_PIKK_ATM_ATM_ST	Q8IUQ4	SIAH1	Q13315	ATM	S19	A24S	24	Missense	distal	5	no	14.359	14.312	PhosphoSitePlus	ICGC;COSMIC	9.540	Down-regulation
Atypical_PIKK_ATM_ATM_ST	Q8IUQ4	SIAH1	Q13315	ATM	S19	Q20K	20	Missense	proximal	1	no	14.359	7.511	PhosphoSitePlus	ICGC;COSMIC	9.540	Loss
Atypical_PIKK_ATM_ATM_ST	Q16204	CCDC6	Q13315	ATM	S26	C27R	27	Missense	proximal	1	no	4.162	9.721	EPSD	ICGC;COSMIC	9.540	Gain
Atypical_PIKK_ATM_ATM_ST	Q16204	CCDC6	Q13315	ATM	S244	P238T	238	Missense	distal	-6	no	10.292	10.281	EPSD	ICGC	9.540	Down-regulation
Atypical_PIKK_ATM_ATM_ST	Q16204	CCDC6	Q13315	ATM	S244	R246I	246	Missense	proximal	2	no	10.292	10.605	EPSD	ICGC;COSMIC;GDSC	9.540	Up-regulation
Atypical_PIKK_ATM_ATM_ST	Q16204	CCDC6	Q13315	ATM	S244	V239I	239	Missense	distal	-5	no	10.292	10.293	EPSD	ICGC	9.540	Up-regulation
Atypical_PIKK_ATM_ATM_ST	Q16204	CCDC6	Q13315	ATM	S254	M258I	258	Missense	distal	4	no	9.470	9.872	EPSD	ICGC;COSMIC	9.540	Gain
Atypical_PIKK_ATM_ATM_ST	Q16204	CCDC6	Q13315	ATM	S328	D333E	333	Missense	distal	5	no	11.359	11.102	EPSD	ICGC	9.540	Down-regulation
Atypical_PIKK_ATM_ATM_ST	Q16204	CCDC6	Q13315	ATM	S328	S327Y	327	Missense	proximal	-1	no	11.359	11.310	EPSD	ICGC	9.540	Down-regulation
Atypical_PIKK_ATM_ATM_ST	Q16204	CCDC6	Q13315	ATM	T357	P358T	358	Missense	proximal	1	no	9.839	4.832	EPSD	ICGC;COSMIC	9.540	Loss
Atypical_PIKK_ATM_ATM_ST	Q16204	CCDC6	Q13315	ATM	T357	P353T	353	Missense	distal	-4	no	9.839	10.125	EPSD	ICGC	9.540	Up-regulation
Atypical_PIKK_ATM_ATM_ST	Q16204	CCDC6	Q13315	ATM	S359	P358T	358	Missense	proximal	-1	no	10.247	10.549	EPSD	ICGC;COSMIC	9.540	Up-regulation
Atypical_PIKK_ATM_ATM_ST	Q16204	CCDC6	Q13315	ATM	S359	P353T	353	Missense	distal	-6	no	10.247	10.236	EPSD	ICGC	9.540	Down-regulation
Atypical_PIKK_ATM_ATM_ST	Q16204	CCDC6	Q13315	ATM	S363	P368H	368	Missense	distal	5	no	11.394	11.352	EPSD	ICGC;COSMIC	9.540	Down-regulation
Atypical_PIKK_ATM_ATM_ST	Q16204	CCDC6	Q13315	ATM	S363	P358T	358	Missense	distal	-5	no	11.394	11.302	EPSD	ICGC;COSMIC	9.540	Down-regulation
Atypical_PIKK_ATM_ATM_ST	Q16204	CCDC6	Q13315	ATM	S363	G369C	369	Missense	distal	6	no	11.394	11.340	EPSD	ICGC;COSMIC	9.540	Down-regulation
Atypical_PIKK_ATM_ATM_ST	Q16204	CCDC6	Q13315	ATM	T380	P381Q	381	Missense	proximal	1	no	6.524	11.326	EPSD	ICGC	9.540	Gain
Atypical_PIKK_ATM_ATM_ST	Q16204	CCDC6	Q13315	ATM	S419	P420L	420	Missense	proximal	1	no	13.282	11.727	EPSD	ICGC	9.540	Down-regulation
Atypical_PIKK_ATM_ATM_ST	Q16204	CCDC6	Q13315	ATM	S419	R425P	425	Missense	distal	6	no	13.282	13.288	EPSD	ICGC	9.540	Up-regulation
Atypical_PIKK_ATM_ATM_ST	Q16204	CCDC6	Q13315	ATM	T434	P437T	437	Missense	distal	3	no	14.518	14.447	PhosphoSitePlus	ICGC;COSMIC	9.540	Down-regulation
Atypical_PIKK_ATM_ATM_ST	Q16204	CCDC6	Q13315	ATM	T434	P440T	440	Missense	distal	6	no	14.518	14.520	PhosphoSitePlus	ICGC	9.540	Up-regulation
Atypical_PIKK_ATM_ATM_ST	Q16204	CCDC6	Q13315	ATM	T434	P430L	430	Missense	distal	-4	no	14.518	14.248	PhosphoSitePlus	ICGC	9.540	Down-regulation
Atypical_PIKK_ATM_ATM_ST	Q16204	CCDC6	Q13315	ATM	S459	S464L	464	Missense	distal	5	no	13.636	13.800	EPSD	ICGC;GDSC	9.540	Up-regulation
Atypical_PIKK_ATM_ATM_ST	Q16204	CCDC6	Q13315	ATM	S459	P461H	461	Missense	proximal	2	no	13.636	13.409	EPSD	ICGC	9.540	Down-regulation
Atypical_PIKK_ATM_ATM_ST	Q16204	CCDC6	Q13315	ATM	S464	P470T	470	Missense	distal	6	no	14.429	14.430	EPSD	ICGC;COSMIC	9.540	Up-regulation
Atypical_PIKK_ATM_ATM_ST	Q16204	CCDC6	Q13315	ATM	S464	S464L	464	Missense	central	0	yes	14.429	0.000	EPSD	ICGC;GDSC	9.540	Loss
Atypical_PIKK_ATM_ATM_ST	Q16204	CCDC6	Q13315	ATM	S464	P461H	461	Missense	distal	-3	no	14.429	14.327	EPSD	ICGC	9.540	Down-regulation
Atypical_PIKK_ATM_ATM_ST	Q16204	CCDC6	Q13315	ATM	S472	P470T	470	Missense	proximal	-2	no	16.050	16.199	EPSD	ICGC;COSMIC	9.540	Up-regulation
Atypical_PIKK_ATM_ATM_ST	Q13098	GPS1	Q13315	ATM	T367	R363Q	363	Missense	distal	-4	no	13.000	13.366	EPSD	ICGC;COSMIC	9.540	Up-regulation
Atypical_PIKK_ATM_ATM_ST	Q15109	AGER	Q13315	ATM	T195	E191G	191	Missense	distal	-4	no	9.967	8.900	EPSD	ICGC;COSMIC	9.540	Loss
Atypical_PIKK_ATM_ATM_ST	Q15109	AGER	Q13315	ATM	T195	A197V	197	Missense	proximal	2	no	9.967	9.658	EPSD	ICGC;COSMIC	9.540	Down-regulation
Atypical_PIKK_ATM_ATM_ST	Q99638	RAD9A	Q13315	ATM	S272	Q273E	273	Missense	proximal	1	no	14.144	8.248	PhosphoSitePlus	ICGC;COSMIC	9.540	Loss
Atypical_PIKK_ATM_ATM_ST	Q99638	RAD9A	Q13315	ATM	S272	L265I	265	Missense	distal	-7	no	14.144	14.068	PhosphoSitePlus	ICGC	9.540	Down-regulation
Atypical_PIKK_ATM_ATM_ST	Q99638	RAD9A	Q13315	ATM	S277	Q273E	273	Missense	distal	-4	no	8.976	9.699	EPSD	ICGC;COSMIC	9.540	Gain
Atypical_PIKK_ATM_ATM_ST	Q99638	RAD9A	Q13315	ATM	S328	P331S	331	Missense	distal	3	no	9.766	9.615	EPSD	ICGC	9.540	Down-regulation
Atypical_PIKK_ATM_ATM_ST	Q99638	RAD9A	Q13315	ATM	S328	P329L	329	Missense	proximal	1	no	9.766	8.212	EPSD	ICGC	9.540	Loss
Atypical_PIKK_ATM_ATM_ST	Q99638	RAD9A	Q13315	ATM	T355	P349S	349	Missense	distal	-6	no	9.761	9.820	EPSD	ICGC;COSMIC	9.540	Up-regulation
Atypical_PIKK_ATM_ATM_ST	Q99638	RAD9A	Q13315	ATM	S375	R374H	374	Missense	proximal	-1	no	9.458	9.628	EPSD	ICGC	9.540	Gain
Atypical_PIKK_ATM_ATM_ST	P40692	MLH1	Q13315	ATM	S388	R389L	389	Missense	proximal	1	no	9.388	9.683	EPSD	ICGC;COSMIC	9.540	Gain
Atypical_PIKK_ATM_ATM_ST	O43683	BUB1	Q13315	ATM	T3	P4Q	4	Missense	proximal	1	no	5.620	10.422	EPSD	ICGC;COSMIC	9.540	Gain
Atypical_PIKK_ATM_ATM_ST	O43683	BUB1	Q13315	ATM	S224	S220F	220	Missense	distal	-4	no	9.940	8.542	EPSD	ICGC;COSMIC	9.540	Loss
Atypical_PIKK_ATM_ATM_ST	O43683	BUB1	Q13315	ATM	S224	H222R	222	Missense	proximal	-2	no	9.940	9.925	EPSD	ICGC;COSMIC	9.540	Down-regulation
Atypical_PIKK_ATM_ATM_ST	O43683	BUB1	Q13315	ATM	S314	E319K	319	Missense	distal	5	no	14.746	14.921	PhosphoSitePlus	ICGC;COSMIC	9.540	Up-regulation
Atypical_PIKK_ATM_ATM_ST	O43683	BUB1	Q13315	ATM	S314	D310Y	310	Missense	distal	-4	no	14.746	13.650	PhosphoSitePlus	ICGC	9.540	Down-regulation
Atypical_PIKK_ATM_ATM_ST	O43683	BUB1	Q13315	ATM	T441	F438C	438	Missense	distal	-3	no	9.809	8.905	EPSD	ICGC;COSMIC	9.540	Loss
Atypical_PIKK_ATM_ATM_ST	O43683	BUB1	Q13315	ATM	S563	R556H	556	Missense	distal	-7	no	9.492	9.578	EPSD	ICGC	9.540	Gain
Atypical_PIKK_ATM_ATM_ST	O43683	BUB1	Q13315	ATM	S596	A603V	603	Missense	distal	7	no	10.601	10.619	EPSD	ICGC;COSMIC	9.540	Up-regulation
Atypical_PIKK_ATM_ATM_ST	O43683	BUB1	Q13315	ATM	S596	P594H	594	Missense	proximal	-2	no	10.601	10.410	EPSD	ICGC	9.540	Down-regulation
Atypical_PIKK_ATM_ATM_ST	O43683	BUB1	Q13315	ATM	S596	T589N	589	Missense	distal	-7	no	10.601	10.496	EPSD	ICGC	9.540	Down-regulation
Atypical_PIKK_ATM_ATM_ST	O43683	BUB1	Q13315	ATM	S596	K595R	595	Missense	proximal	-1	no	10.601	10.419	EPSD	ICGC;COSMIC	9.540	Down-regulation
Atypical_PIKK_ATM_ATM_ST	O43683	BUB1	Q13315	ATM	S596	G598E	598	Missense	proximal	2	no	10.601	11.970	EPSD	ICGC;COSMIC	9.540	Up-regulation
Atypical_PIKK_ATM_ATM_ST	O43683	BUB1	Q13315	ATM	T609	A603V	603	Missense	distal	-6	no	11.186	10.949	EPSD	ICGC;COSMIC	9.540	Down-regulation
Atypical_PIKK_ATM_ATM_ST	O43683	BUB1	Q13315	ATM	T609	F611L	611	Missense	proximal	2	no	11.186	11.420	EPSD	ICGC	9.540	Up-regulation
Atypical_PIKK_ATM_ATM_ST	O43683	BUB1	Q13315	ATM	S655	E659K	659	Missense	distal	4	no	10.998	11.376	EPSD	ICGC;COSMIC	9.540	Up-regulation
Atypical_PIKK_ATM_ATM_ST	O43683	BUB1	Q13315	ATM	S679	A673E	673	Missense	distal	-6	no	13.608	13.816	EPSD	ICGC	9.540	Up-regulation
Atypical_PIKK_ATM_ATM_ST	O00213	APBB1	Q13315	ATM	S175	L173P	173	Missense	proximal	-2	no	12.943	13.096	EPSD	ICGC;COSMIC	9.540	Up-regulation
Atypical_PIKK_ATM_ATM_ST	O00213	APBB1	Q13315	ATM	S175	P176H	176	Missense	proximal	1	no	12.943	2.835	EPSD	ICGC;COSMIC	9.540	Loss
Atypical_PIKK_ATM_ATM_ST	O00213	APBB1	Q13315	ATM	S205	R200L	200	Missense	distal	-5	no	9.690	9.637	EPSD	ICGC;COSMIC	9.540	Down-regulation
Atypical_PIKK_ATM_ATM_ST	Q86U86	PBRM1	Q13315	ATM	S10	P11H	11	Missense	proximal	1	no	10.980	0.873	EPSD	ICGC	9.540	Loss
Atypical_PIKK_ATM_ATM_ST	Q86U86	PBRM1	Q13315	ATM	S10	G17V	17	Missense	distal	7	no	10.980	10.987	EPSD	ICGC;COSMIC	9.540	Up-regulation
Atypical_PIKK_ATM_ATM_ST	Q86U86	PBRM1	Q13315	ATM	S10	R7I	7	Missense	distal	-3	no	10.980	10.909	EPSD	ICGC	9.540	Down-regulation
Atypical_PIKK_ATM_ATM_ST	Q86U86	PBRM1	Q13315	ATM	S89	P82Q	82	Missense	distal	-7	no	13.544	13.581	EPSD	ICGC	9.540	Up-regulation
Atypical_PIKK_ATM_ATM_ST	Q86U86	PBRM1	Q13315	ATM	S131	A136D	136	Missense	distal	5	no	9.512	9.550	EPSD	ICGC	9.540	Gain
Atypical_PIKK_ATM_ATM_ST	Q86U86	PBRM1	Q13315	ATM	S502	D495E	495	Missense	distal	-7	no	9.054	9.632	EPSD	ICGC	9.540	Gain
Atypical_PIKK_ATM_ATM_ST	Q86U86	PBRM1	Q13315	ATM	S605	Q606K	606	Missense	proximal	1	no	14.316	7.467	EPSD	ICGC;COSMIC	9.540	Loss
Atypical_PIKK_ATM_ATM_ST	Q86U86	PBRM1	Q13315	ATM	S605	S605Y	605	Missense	central	0	yes	14.316	0.000	EPSD	ICGC;COSMIC	9.540	Loss
Atypical_PIKK_ATM_ATM_ST	Q86U86	PBRM1	Q13315	ATM	S605	R598M	598	Missense	distal	-7	no	14.316	14.239	EPSD	ICGC;COSMIC	9.540	Down-regulation
Atypical_PIKK_ATM_ATM_ST	Q86U86	PBRM1	Q13315	ATM	S636	K638R	638	Missense	proximal	2	no	10.096	9.918	EPSD	ICGC;COSMIC	9.540	Down-regulation
Atypical_PIKK_ATM_ATM_ST	Q86U86	PBRM1	Q13315	ATM	S636	A635D	635	Missense	proximal	-1	no	10.096	10.202	EPSD	ICGC	9.540	Up-regulation
Atypical_PIKK_ATM_ATM_ST	Q86U86	PBRM1	Q13315	ATM	S636	P629L	629	Missense	distal	-7	no	10.096	9.744	EPSD	ICGC	9.540	Down-regulation
Atypical_PIKK_ATM_ATM_ST	Q86U86	PBRM1	Q13315	ATM	S931	A937V	937	Missense	distal	6	no	12.608	12.578	EPSD	ICGC;COSMIC	9.540	Down-regulation
Atypical_PIKK_ATM_ATM_ST	Q86U86	PBRM1	Q13315	ATM	S931	E927Q	927	Missense	distal	-4	no	12.608	11.885	EPSD	ICGC;COSMIC	9.540	Down-regulation
Atypical_PIKK_ATM_ATM_ST	Q86U86	PBRM1	Q13315	ATM	S931	E924K	924	Missense	distal	-7	no	12.608	11.940	EPSD	ICGC;COSMIC	9.540	Down-regulation
Atypical_PIKK_ATM_ATM_ST	Q86U86	PBRM1	Q13315	ATM	S935	A937V	937	Missense	proximal	2	no	9.702	9.393	EPSD	ICGC;COSMIC	9.540	Loss
Atypical_PIKK_ATM_ATM_ST	Q86U86	PBRM1	Q13315	ATM	S948	N955K	955	Missense	distal	7	no	16.582	16.590	PhosphoSitePlus	ICGC	9.540	Up-regulation
Atypical_PIKK_ATM_ATM_ST	Q86U86	PBRM1	Q13315	ATM	S1116	D1118V	1118	Missense	proximal	2	no	10.171	8.899	EPSD	ICGC	9.540	Loss
Atypical_PIKK_ATM_ATM_ST	Q86U86	PBRM1	Q13315	ATM	S1280	D1286N	1286	Missense	distal	6	no	12.779	12.791	EPSD	ICGC;COSMIC	9.540	Up-regulation
Atypical_PIKK_ATM_ATM_ST	Q86U86	PBRM1	Q13315	ATM	S1280	E1287K	1287	Missense	distal	7	no	12.779	12.806	EPSD	ICGC;COSMIC	9.540	Up-regulation
Atypical_PIKK_ATM_ATM_ST	Q86U86	PBRM1	Q13315	ATM	S1280	D1285N	1285	Missense	distal	5	no	12.779	12.667	EPSD	ICGC;COSMIC	9.540	Down-regulation
Atypical_PIKK_ATM_ATM_ST	Q86U86	PBRM1	Q13315	ATM	S1280	F1277L	1277	Missense	distal	-3	no	12.779	11.916	EPSD	ICGC;COSMIC	9.540	Down-regulation
Atypical_PIKK_ATM_ATM_ST	Q86U86	PBRM1	Q13315	ATM	S1280	E1287D	1287	Missense	distal	7	no	12.779	12.791	EPSD	ICGC;COSMIC	9.540	Up-regulation
Atypical_PIKK_ATM_ATM_ST	Q86U86	PBRM1	Q13315	ATM	S1280	L1279I	1279	Missense	proximal	-1	no	12.779	12.693	EPSD	ICGC	9.540	Down-regulation
Atypical_PIKK_ATM_ATM_ST	Q86U86	PBRM1	Q13315	ATM	S1280	A1281S	1281	Missense	proximal	1	no	12.779	7.875	EPSD	ICGC;COSMIC	9.540	Loss
Atypical_PIKK_ATM_ATM_ST	Q86U86	PBRM1	Q13315	ATM	S1280	L1274V	1274	Missense	distal	-6	no	12.779	12.810	EPSD	ICGC;COSMIC	9.540	Up-regulation
Atypical_PIKK_ATM_ATM_ST	Q86U86	PBRM1	Q13315	ATM	S1280	F1277C	1277	Missense	distal	-3	no	12.779	11.875	EPSD	ICGC;COSMIC	9.540	Down-regulation
Atypical_PIKK_ATM_ATM_ST	Q99504	EYA3	Q13315	ATM	S256	L254M	254	Missense	proximal	-2	no	10.141	10.092	EPSD	ICGC;COSMIC	9.540	Down-regulation
Atypical_PIKK_ATM_ATM_ST	Q99504	EYA3	Q13315	ATM	S438	L445I	445	Missense	distal	7	no	11.421	11.433	EPSD	ICGC	9.540	Up-regulation
Atypical_PIKK_ATM_ATM_ST	Q8TAQ2	SMARCC2	Q13315	ATM	T230	T230N	230	Missense	central	0	yes	12.851	0.000	EPSD	ICGC	9.540	Loss
Atypical_PIKK_ATM_ATM_ST	Q8TAQ2	SMARCC2	Q13315	ATM	S302	R301H	301	Missense	proximal	-1	no	9.542	9.712	EPSD	ICGC;COSMIC	9.540	Up-regulation
Atypical_PIKK_ATM_ATM_ST	Q8TAQ2	SMARCC2	Q13315	ATM	S302	P305H	305	Missense	distal	3	no	9.542	9.614	EPSD	ICGC;COSMIC	9.540	Up-regulation
Atypical_PIKK_ATM_ATM_ST	Q8TAQ2	SMARCC2	Q13315	ATM	S302	S302Y	302	Missense	central	0	yes	9.542	0.000	EPSD	ICGC	9.540	Loss
Atypical_PIKK_ATM_ATM_ST	Q8TAQ2	SMARCC2	Q13315	ATM	S304	R301H	301	Missense	distal	-3	no	10.849	10.204	EPSD	ICGC;COSMIC	9.540	Down-regulation
Atypical_PIKK_ATM_ATM_ST	Q8TAQ2	SMARCC2	Q13315	ATM	S304	P305H	305	Missense	proximal	1	no	10.849	0.742	EPSD	ICGC;COSMIC	9.540	Loss
Atypical_PIKK_ATM_ATM_ST	Q8TAQ2	SMARCC2	Q13315	ATM	S304	S302Y	302	Missense	proximal	-2	no	10.849	10.679	EPSD	ICGC	9.540	Down-regulation
Atypical_PIKK_ATM_ATM_ST	Q8TAQ2	SMARCC2	Q13315	ATM	T308	R301H	301	Missense	distal	-7	no	10.631	10.716	EPSD	ICGC;COSMIC	9.540	Up-regulation
Atypical_PIKK_ATM_ATM_ST	Q8TAQ2	SMARCC2	Q13315	ATM	T308	P305H	305	Missense	distal	-3	no	10.631	10.529	EPSD	ICGC;COSMIC	9.540	Down-regulation
Atypical_PIKK_ATM_ATM_ST	Q8TAQ2	SMARCC2	Q13315	ATM	T308	S302Y	302	Missense	distal	-6	no	10.631	10.381	EPSD	ICGC	9.540	Down-regulation
Atypical_PIKK_ATM_ATM_ST	Q8TAQ2	SMARCC2	Q13315	ATM	S369	D366E	366	Missense	distal	-3	no	9.822	9.417	EPSD	ICGC	9.540	Loss
Atypical_PIKK_ATM_ATM_ST	Q8TAQ2	SMARCC2	Q13315	ATM	S369	G375C	375	Missense	distal	6	no	9.822	9.769	EPSD	ICGC;COSMIC	9.540	Down-regulation
Atypical_PIKK_ATM_ATM_ST	Q8TAQ2	SMARCC2	Q13315	ATM	S555	P562A	562	Missense	distal	7	no	14.022	14.034	EPSD	ICGC	9.540	Up-regulation
Atypical_PIKK_ATM_ATM_ST	Q8TAQ2	SMARCC2	Q13315	ATM	S969	P974T	974	Missense	distal	5	no	13.793	13.595	PhosphoSitePlus	ICGC	9.540	Down-regulation
Atypical_PIKK_ATM_ATM_ST	Q8TAQ2	SMARCC2	Q13315	ATM	S969	P974A	974	Missense	distal	5	no	13.793	13.659	PhosphoSitePlus	ICGC;COSMIC	9.540	Down-regulation
Atypical_PIKK_ATM_ATM_ST	Q15797	SMAD1	Q13315	ATM	S187	P183S	183	Missense	distal	-4	no	9.315	9.984	EPSD	ICGC	9.540	Gain
Atypical_PIKK_ATM_ATM_ST	Q15797	SMAD1	Q13315	ATM	S195	P188T	188	Missense	distal	-7	no	9.488	9.643	EPSD	ICGC;COSMIC	9.540	Gain
Atypical_PIKK_ATM_ATM_ST	Q15797	SMAD1	Q13315	ATM	S239	D237Y	237	Missense	proximal	-2	no	14.556	14.685	PhosphoSitePlus	ICGC	9.540	Up-regulation
Atypical_PIKK_ATM_ATM_ST	Q15797	SMAD1	Q13315	ATM	S239	T244S	244	Missense	distal	5	no	14.556	14.573	PhosphoSitePlus	ICGC;COSMIC	9.540	Up-regulation
Atypical_PIKK_ATM_ATM_ST	Q15797	SMAD1	Q13315	ATM	T452	W446L	446	Missense	distal	-6	no	10.635	10.696	EPSD	ICGC;COSMIC	9.540	Up-regulation
Atypical_PIKK_ATM_ATM_ST	Q15797	SMAD1	Q13315	ATM	T452	W446C	446	Missense	distal	-6	no	10.635	10.604	EPSD	ICGC	9.540	Down-regulation
Atypical_PIKK_ATM_ATM_ST	Q15797	SMAD1	Q13315	ATM	T452	P457L	457	Missense	distal	5	no	10.635	10.618	EPSD	ICGC;COSMIC	9.540	Down-regulation
Atypical_PIKK_ATM_ATM_ST	Q15797	SMAD1	Q13315	ATM	S456	P457L	457	Missense	proximal	1	no	10.020	8.465	EPSD	ICGC;COSMIC	9.540	Loss
Atypical_PIKK_ATM_ATM_ST	P55072	VCP	Q13315	ATM	S78	V71I	71	Missense	distal	-7	no	10.334	10.150	EPSD	ICGC;COSMIC	9.540	Down-regulation
Atypical_PIKK_ATM_ATM_ST	P55072	VCP	Q13315	ATM	S78	D75E	75	Missense	distal	-3	no	10.334	9.928	EPSD	ICGC;COSMIC	9.540	Down-regulation
Atypical_PIKK_ATM_ATM_ST	P55072	VCP	Q13315	ATM	S78	D79V	79	Missense	proximal	1	no	10.334	3.370	EPSD	ICGC;COSMIC	9.540	Loss
Atypical_PIKK_ATM_ATM_ST	P55072	VCP	Q13315	ATM	S78	L72F	72	Missense	distal	-6	no	10.334	10.091	EPSD	ICGC	9.540	Down-regulation
Atypical_PIKK_ATM_ATM_ST	P55072	VCP	Q13315	ATM	S78	R83W	83	Missense	distal	5	no	10.334	10.358	EPSD	ICGC;COSMIC	9.540	Up-regulation
Atypical_PIKK_ATM_ATM_ST	P55072	VCP	Q13315	ATM	S326	R322W	322	Missense	distal	-4	no	14.782	14.306	PhosphoSitePlus	ICGC;COSMIC	9.540	Down-regulation
Atypical_PIKK_ATM_ATM_ST	P55072	VCP	Q13315	ATM	S784	P783T	783	Missense	proximal	-1	no	11.612	11.914	EPSD	ICGC;COSMIC	9.540	Up-regulation
Atypical_PIKK_ATM_ATM_ST	P50542	PEX5	Q13315	ATM	S51	K52E	52	Missense	proximal	1	no	9.362	10.314	EPSD	ICGC;COSMIC	9.540	Gain
Atypical_PIKK_ATM_ATM_ST	P50542	PEX5	Q13315	ATM	S155	D150Y	150	Missense	distal	-5	no	10.810	11.044	EPSD	ICGC;COSMIC	9.540	Up-regulation
TK_Trk_NTRK1_Y	P29353	SHC1	P04629	NTRK1	Y162	Y162C	162	Missense	central	0	yes	0.000	0.000	EPSD	ICGC;COSMIC	0.000	Loss
CMGC_MAPK_p38_MAPK13_ST	O00418	EEF2K	O15264	MAPK13	S61	S66R	66	Missense	distal	5	no	39.058	39.195	EPSD	ICGC	38.013	Up-regulation
CMGC_MAPK_p38_MAPK13_ST	O00418	EEF2K	O15264	MAPK13	S74	P75A	75	Missense	proximal	1	no	50.260	22.483	EPSD	ICGC;COSMIC	38.013	Loss
CMGC_MAPK_p38_MAPK13_ST	O00418	EEF2K	O15264	MAPK13	S74	P75L	75	Missense	proximal	1	no	50.260	37.828	EPSD	ICGC;COSMIC	38.013	Loss
CMGC_MAPK_p38_MAPK13_ST	O00418	EEF2K	O15264	MAPK13	S74	S71F	71	Missense	distal	-3	no	50.260	49.021	EPSD	ICGC;COSMIC	38.013	Down-regulation
CMGC_MAPK_p38_MAPK13_ST	O00418	EEF2K	O15264	MAPK13	S74	F79L	79	Missense	distal	5	no	50.260	50.364	EPSD	ICGC	38.013	Up-regulation
CMGC_MAPK_p38_MAPK13_ST	O00418	EEF2K	O15264	MAPK13	S78	F79L	79	Missense	proximal	1	no	24.984	39.328	EPSD	ICGC	38.013	Gain
CMGC_MAPK_p38_MAPK13_ST	O00418	EEF2K	O15264	MAPK13	S359	Q361R	361	Missense	proximal	2	no	53.316	54.906	EPSD;PhosphoSitePlus	ICGC	38.013	Up-regulation
CMGC_MAPK_p38_MAPK13_ST	O00418	EEF2K	O15264	MAPK13	S359	P360L	360	Missense	proximal	1	no	53.316	40.884	EPSD;PhosphoSitePlus	ICGC	38.013	Down-regulation
CMGC_MAPK_p38_MAPK13_ST	O00418	EEF2K	O15264	MAPK13	T401	S404C	404	Missense	distal	3	no	46.484	45.806	EPSD	ICGC	38.013	Down-regulation
CMGC_MAPK_p38_MAPK13_ST	O00418	EEF2K	O15264	MAPK13	S404	S404C	404	Missense	central	0	yes	47.258	0.000	EPSD	ICGC	38.013	Loss
CMGC_MAPK_p38_MAPK13_ST	O00418	EEF2K	O15264	MAPK13	S404	H411Y	411	Missense	distal	7	no	47.258	47.136	EPSD	ICGC;COSMIC	38.013	Down-regulation
CMGC_MAPK_p38_MAPK13_ST	P10636	MAPT	O15264	MAPK13	T111	D116E	116	Missense	distal	5	no	38.311	38.157	EPSD	ICGC;COSMIC	38.013	Down-regulation
CMGC_MAPK_p38_MAPK13_ST	P10636	MAPT	O15264	MAPK13	T123	E127K	127	Missense	distal	4	no	36.928	38.171	EPSD	ICGC	38.013	Gain
CMGC_MAPK_p38_MAPK13_ST	P10636	MAPT	O15264	MAPK13	S228	P233H	233	Missense	distal	5	no	46.272	46.289	EPSD	ICGC;COSMIC	38.013	Up-regulation
CMGC_MAPK_p38_MAPK13_ST	P10636	MAPT	O15264	MAPK13	S228	S232F	232	Missense	distal	4	no	46.272	45.095	EPSD	ICGC	38.013	Down-regulation
CMGC_MAPK_p38_MAPK13_ST	P10636	MAPT	O15264	MAPK13	S228	D225N	225	Missense	distal	-3	no	46.272	47.073	EPSD	ICGC	38.013	Up-regulation
CMGC_MAPK_p38_MAPK13_ST	P10636	MAPT	O15264	MAPK13	S228	V224I	224	Missense	distal	-4	no	46.272	43.942	EPSD	ICGC;COSMIC	38.013	Down-regulation
CMGC_MAPK_p38_MAPK13_ST	P10636	MAPT	O15264	MAPK13	S232	P233H	233	Missense	proximal	1	no	50.046	21.661	EPSD	ICGC;COSMIC	38.013	Loss
CMGC_MAPK_p38_MAPK13_ST	P10636	MAPT	O15264	MAPK13	S232	S232F	232	Missense	central	0	yes	50.046	0.000	EPSD	ICGC	38.013	Loss
CMGC_MAPK_p38_MAPK13_ST	P10636	MAPT	O15264	MAPK13	S232	D225N	225	Missense	distal	-7	no	50.046	50.637	EPSD	ICGC	38.013	Up-regulation
CMGC_MAPK_p38_MAPK13_ST	P10636	MAPT	O15264	MAPK13	S232	P239Q	239	Missense	distal	7	no	50.046	49.539	EPSD	ICGC;COSMIC	38.013	Down-regulation
CMGC_MAPK_p38_MAPK13_ST	P10636	MAPT	O15264	MAPK13	S238	P233H	233	Missense	distal	-5	no	52.512	52.692	EPSD	ICGC;COSMIC	38.013	Up-regulation
CMGC_MAPK_p38_MAPK13_ST	P10636	MAPT	O15264	MAPK13	S238	S232F	232	Missense	distal	-6	no	52.512	51.402	EPSD	ICGC	38.013	Down-regulation
CMGC_MAPK_p38_MAPK13_ST	P10636	MAPT	O15264	MAPK13	S238	P239Q	239	Missense	proximal	1	no	52.512	43.849	EPSD	ICGC;COSMIC	38.013	Down-regulation
CMGC_MAPK_p38_MAPK13_ST	P10636	MAPT	O15264	MAPK13	S428	S427F	427	Missense	proximal	-1	no	51.416	50.610	EPSD	ICGC	38.013	Down-regulation
CMGC_MAPK_p38_MAPK13_ST	P10636	MAPT	O15264	MAPK13	S438	Y441H	441	Missense	distal	3	no	49.548	49.725	EPSD	ICGC;COSMIC	38.013	Up-regulation
CMGC_MAPK_p38_MAPK13_ST	P10636	MAPT	O15264	MAPK13	S447	Y441H	441	Missense	distal	-6	no	43.110	43.534	EPSD	ICGC;COSMIC	38.013	Up-regulation
CMGC_MAPK_p38_MAPK13_ST	P10636	MAPT	O15264	MAPK13	S516	G521R	521	Missense	distal	5	no	57.896	58.394	EPSD	ICGC;COSMIC	38.013	Up-regulation
CMGC_MAPK_p38_MAPK13_ST	P10636	MAPT	O15264	MAPK13	S519	G521R	521	Missense	proximal	2	no	62.266	64.728	EPSD	ICGC;COSMIC	38.013	Up-regulation
CMGC_MAPK_p38_MAPK13_ST	P10636	MAPT	O15264	MAPK13	T522	G521R	521	Missense	proximal	-1	no	58.788	59.268	EPSD	ICGC;COSMIC	38.013	Up-regulation
CMGC_MAPK_p38_MAPK13_ST	P10636	MAPT	O15264	MAPK13	S525	G521R	521	Missense	distal	-4	no	42.544	45.473	EPSD	ICGC;COSMIC	38.013	Up-regulation
CMGC_MAPK_p38_MAPK13_ST	P10636	MAPT	O15264	MAPK13	S527	G521R	521	Missense	distal	-6	no	43.486	44.406	EPSD	ICGC;COSMIC	38.013	Up-regulation
CMGC_MAPK_p38_MAPK13_ST	Q00613	HSF1	O15264	MAPK13	S230	P223L	223	Missense	distal	-7	no	43.527	43.689	EPSD	ICGC	38.013	Up-regulation
CMGC_MAPK_p38_MAPK13_ST	Q00613	HSF1	O15264	MAPK13	S244	P239L	239	Missense	distal	-5	no	43.089	43.375	EPSD	ICGC;CCLE	38.013	Up-regulation
CMGC_MAPK_p38_MAPK13_ST	Q00613	HSF1	O15264	MAPK13	S275	A278T	278	Missense	distal	3	no	42.780	43.086	EPSD	ICGC	38.013	Up-regulation
CMGC_MAPK_p38_MAPK13_ST	Q00613	HSF1	O15264	MAPK13	S279	A278T	278	Missense	proximal	-1	no	43.061	43.896	EPSD	ICGC	38.013	Up-regulation
CMGC_MAPK_p38_MAPK13_ST	Q00613	HSF1	O15264	MAPK13	S419	S421L	421	Missense	proximal	2	no	52.329	51.259	EPSD	ICGC;COSMIC	38.013	Down-regulation
CMGC_MAPK_p38_MAPK13_ST	Q00613	HSF1	O15264	MAPK13	S419	S419G	419	Missense	central	0	yes	52.329	0.000	EPSD	ICGC;COSMIC	38.013	Loss
CMGC_MAPK_p38_MAPK13_ST	Q00613	HSF1	O15264	MAPK13	S444	A437S	437	Missense	distal	-7	no	44.546	46.523	EPSD	ICGC;COSMIC	38.013	Up-regulation
CMGC_MAPK_p38_MAPK13_ST	P16949	STMN1	O15264	MAPK13	S25	L24F	24	Missense	proximal	-1	no	47.830	47.778	PhosphoSitePlus;EPSD	ICGC;COSMIC	38.013	Down-regulation
CMGC_MAPK_p38_MAPK13_ST	P16949	STMN1	O15264	MAPK13	S25	E30K	30	Missense	distal	5	no	47.830	48.098	PhosphoSitePlus;EPSD	ICGC	38.013	Up-regulation
CMGC_MAPK_p38_MAPK13_ST	P16949	STMN1	O15264	MAPK13	S25	E30Q	30	Missense	distal	5	no	47.830	48.146	PhosphoSitePlus;EPSD	ICGC;COSMIC	38.013	Up-regulation
CMGC_MAPK_p38_MAPK13_ST	P16949	STMN1	O15264	MAPK13	S25	S31P	31	Missense	distal	6	no	47.830	47.766	PhosphoSitePlus;EPSD	ICGC;COSMIC	38.013	Down-regulation
CMGC_MAPK_p38_MAPK13_ST	P16949	STMN1	O15264	MAPK13	S31	L24F	24	Missense	distal	-7	no	41.372	40.672	EPSD	ICGC;COSMIC	38.013	Down-regulation
CMGC_MAPK_p38_MAPK13_ST	P16949	STMN1	O15264	MAPK13	S31	E30K	30	Missense	proximal	-1	no	41.372	41.942	EPSD	ICGC	38.013	Up-regulation
CMGC_MAPK_p38_MAPK13_ST	P16949	STMN1	O15264	MAPK13	S31	E30Q	30	Missense	proximal	-1	no	41.372	42.119	EPSD	ICGC;COSMIC	38.013	Up-regulation
CMGC_MAPK_p38_MAPK13_ST	P16949	STMN1	O15264	MAPK13	S31	S31P	31	Missense	central	0	yes	41.372	0.000	EPSD	ICGC;COSMIC	38.013	Loss
CMGC_MAPK_p38_MAPK13_ST	P16949	STMN1	O15264	MAPK13	S38	S31P	31	Missense	distal	-7	no	52.410	50.989	EPSD;PhosphoSitePlus	ICGC;COSMIC	38.013	Down-regulation
CMGC_MAPK_p38_MAPK13_ST	Q13501	SQSTM1	O15264	MAPK13	S28	R21H	21	Missense	distal	-7	no	41.178	38.632	EPSD	ICGC;GDSC;CCLE	38.013	Down-regulation
CMGC_MAPK_p38_MAPK13_ST	Q13501	SQSTM1	O15264	MAPK13	S28	P29S	29	Missense	proximal	1	no	41.178	15.626	EPSD	ICGC;COSMIC	38.013	Loss
CMGC_MAPK_p38_MAPK13_ST	Q13501	SQSTM1	O15264	MAPK13	S170	K165R	165	Missense	distal	-5	no	44.023	43.791	EPSD	ICGC;COSMIC	38.013	Down-regulation
CMGC_MAPK_p38_MAPK13_ST	Q13501	SQSTM1	O15264	MAPK13	S170	A167E	167	Missense	distal	-3	no	44.023	43.841	EPSD	ICGC	38.013	Down-regulation
CMGC_MAPK_p38_MAPK13_ST	Q13501	SQSTM1	O15264	MAPK13	S170	K165N	165	Missense	distal	-5	no	44.023	43.976	EPSD	ICGC	38.013	Down-regulation
CMGC_MAPK_p38_MAPK13_ST	Q13501	SQSTM1	O15264	MAPK13	S207	N205S	205	Missense	proximal	-2	no	46.813	46.619	EPSD	ICGC;COSMIC	38.013	Down-regulation
CMGC_MAPK_p38_MAPK13_ST	Q13501	SQSTM1	O15264	MAPK13	S284	S284L	284	Missense	central	0	yes	43.411	0.000	EPSD	ICGC;COSMIC	38.013	Loss
CMGC_MAPK_p38_MAPK13_ST	Q13501	SQSTM1	O15264	MAPK13	S306	A303T	303	Missense	distal	-3	no	41.052	42.343	EPSD	ICGC;COSMIC;CCLE	38.013	Up-regulation
CMGC_MAPK_p38_MAPK13_ST	Q13501	SQSTM1	O15264	MAPK13	S306	A308P	308	Missense	proximal	2	no	41.052	42.514	EPSD	ICGC;COSMIC	38.013	Up-regulation
CMGC_MAPK_p38_MAPK13_ST	P30281	CCND3	O15264	MAPK13	S259	S259A	259	Missense	central	0	yes	43.189	0.000	EPSD	ICGC;COSMIC	38.013	Loss
CMGC_MAPK_p38_MAPK13_ST	P30281	CCND3	O15264	MAPK13	S259	A266E	266	Missense	distal	7	no	43.189	42.811	EPSD	ICGC;COSMIC	38.013	Down-regulation
CMGC_MAPK_p38_MAPK13_ST	P30281	CCND3	O15264	MAPK13	S259	S262I	262	Missense	distal	3	no	43.189	42.710	EPSD	ICGC;COSMIC	38.013	Down-regulation
CMGC_MAPK_p38_MAPK13_ST	P30281	CCND3	O15264	MAPK13	S264	S259A	259	Missense	distal	-5	no	54.196	54.548	EPSD	ICGC;COSMIC	38.013	Up-regulation
CMGC_MAPK_p38_MAPK13_ST	P30281	CCND3	O15264	MAPK13	S264	A266E	266	Missense	proximal	2	no	54.196	54.918	EPSD	ICGC;COSMIC	38.013	Up-regulation
CMGC_MAPK_p38_MAPK13_ST	P30281	CCND3	O15264	MAPK13	S264	S262I	262	Missense	proximal	-2	no	54.196	52.804	EPSD	ICGC;COSMIC	38.013	Down-regulation
CMGC_MAPK_p38_MAPK13_ST	P30281	CCND3	O15264	MAPK13	S282	T283P	283	Missense	proximal	1	no	18.736	40.812	EPSD	ICGC;COSMIC	38.013	Gain
CMGC_MAPK_p38_MAPK13_ST	P30281	CCND3	O15264	MAPK13	T283	A289D	289	Missense	distal	6	no	47.606	47.695	PhosphoSitePlus	ICGC	38.013	Up-regulation
CMGC_MAPK_p38_MAPK13_ST	P30281	CCND3	O15264	MAPK13	T283	I290K	290	Missense	distal	7	no	47.606	48.396	PhosphoSitePlus	ICGC;COSMIC;CCLE	38.013	Up-regulation
CMGC_MAPK_p38_MAPK13_ST	P30281	CCND3	O15264	MAPK13	T283	I290T	290	Missense	distal	7	no	47.606	49.492	PhosphoSitePlus	ICGC;COSMIC;CCLE	38.013	Up-regulation
CMGC_MAPK_p38_MAPK13_ST	P30281	CCND3	O15264	MAPK13	T283	T283P	283	Missense	central	0	yes	47.606	0.000	PhosphoSitePlus	ICGC;COSMIC	38.013	Loss
CMGC_MAPK_p38_MAPK13_ST	P30281	CCND3	O15264	MAPK13	T283	D286A	286	Missense	distal	3	no	47.606	47.612	PhosphoSitePlus	ICGC	38.013	Up-regulation
STE_STE20_NinaC_MYO3A_ST	Q8NEV4	MYO3A	Q8NEV4	MYO3A	T178	R181H	181	Missense	distal	3	no	9.069	9.045	EPSD;PhosphoSitePlus	ICGC;COSMIC	3.030	Down-regulation
STE_STE20_NinaC_MYO3A_ST	Q8NEV4	MYO3A	Q8NEV4	MYO3A	T178	R182Q	182	Missense	distal	4	no	9.069	8.116	EPSD;PhosphoSitePlus	ICGC;COSMIC	3.030	Down-regulation
STE_STE20_NinaC_MYO3A_ST	Q8NEV4	MYO3A	Q8NEV4	MYO3A	T184	R181H	181	Missense	distal	-3	no	8.742	8.650	EPSD;PhosphoSitePlus	ICGC;COSMIC	3.030	Down-regulation
STE_STE20_NinaC_MYO3A_ST	Q8NEV4	MYO3A	Q8NEV4	MYO3A	T184	R182Q	182	Missense	proximal	-2	no	8.742	8.773	EPSD;PhosphoSitePlus	ICGC;COSMIC	3.030	Up-regulation
STE_STE20_NinaC_MYO3A_ST	Q8NEV4	MYO3A	Q8NEV4	MYO3A	T288	G292C	292	Missense	distal	4	no	2.492	3.056	EPSD	ICGC;COSMIC	3.030	Gain
STE_STE20_NinaC_MYO3A_ST	Q8NEV4	MYO3A	Q8NEV4	MYO3A	S335	R331G	331	Missense	distal	-4	no	3.416	3.418	EPSD	ICGC	3.030	Up-regulation
STE_STE20_NinaC_MYO3A_ST	Q8NEV4	MYO3A	Q8NEV4	MYO3A	S335	R331L	331	Missense	distal	-4	no	3.416	3.458	EPSD	ICGC	3.030	Up-regulation
STE_STE20_NinaC_MYO3A_ST	Q8NEV4	MYO3A	Q8NEV4	MYO3A	S335	D342Y	342	Missense	distal	7	no	3.416	3.321	EPSD	ICGC;COSMIC	3.030	Down-regulation
STE_STE20_NinaC_MYO3A_ST	Q8NEV4	MYO3A	Q8NEV4	MYO3A	S335	D341Y	341	Missense	distal	6	no	3.416	3.358	EPSD	ICGC;COSMIC	3.030	Down-regulation
STE_STE20_NinaC_MYO3A_ST	Q8NEV4	MYO3A	Q8NEV4	MYO3A	T919	V926I	926	Missense	distal	7	no	9.799	9.793	PhosphoSitePlus;EPSD	ICGC	3.030	Down-regulation
TK_Src_SrcA_FYN_Y	Q12879	GRIN2A	P06241	FYN	Y1118	D1121N	1121	Missense	distal	3	no	3.737	4.438	PhosphoSitePlus;EPSD	ICGC;COSMIC	3.469	Up-regulation
TK_Src_SrcA_FYN_Y	Q12879	GRIN2A	P06241	FYN	Y1187	D1182N	1182	Missense	distal	-5	no	4.093	3.710	EPSD;PhosphoSitePlus	ICGC;COSMIC	3.469	Down-regulation
TK_Src_SrcA_FYN_Y	Q12879	GRIN2A	P06241	FYN	Y1187	K1189M	1189	Missense	proximal	2	no	4.093	3.649	EPSD;PhosphoSitePlus	ICGC;COSMIC	3.469	Down-regulation
TK_Src_SrcA_FYN_Y	Q12879	GRIN2A	P06241	FYN	Y1246	G1243E	1243	Missense	distal	-3	no	4.092	4.267	EPSD;PhosphoSitePlus	ICGC;COSMIC	3.469	Up-regulation
TK_Src_SrcA_FYN_Y	Q12879	GRIN2A	P06241	FYN	Y1246	G1243W	1243	Missense	distal	-3	no	4.092	-0.165	EPSD;PhosphoSitePlus	ICGC;COSMIC	3.469	Loss
TK_Src_SrcA_FYN_Y	Q12879	GRIN2A	P06241	FYN	Y1267	G1263R	1263	Missense	distal	-4	no	7.932	8.740	EPSD;PhosphoSitePlus	ICGC;COSMIC	3.469	Up-regulation
TK_Src_SrcA_FYN_Y	Q12879	GRIN2A	P06241	FYN	Y1267	W1271L	1271	Missense	distal	4	no	7.932	8.216	EPSD;PhosphoSitePlus	ICGC;COSMIC	3.469	Up-regulation
TK_Src_SrcA_FYN_Y	Q12879	GRIN2A	P06241	FYN	Y1292	D1293N	1293	Missense	proximal	1	no	5.278	4.407	EPSD	ICGC;COSMIC	3.469	Down-regulation
TK_Src_SrcA_FYN_Y	Q12879	GRIN2A	P06241	FYN	Y1292	S1287R	1287	Missense	distal	-5	no	5.278	5.666	EPSD	ICGC	3.469	Up-regulation
TK_Src_SrcA_FYN_Y	Q12879	GRIN2A	P06241	FYN	Y1292	P1299H	1299	Missense	distal	7	no	5.278	5.237	EPSD	ICGC	3.469	Down-regulation
TK_Src_SrcA_FYN_Y	Q12879	GRIN2A	P06241	FYN	Y1292	N1294D	1294	Missense	proximal	2	no	5.278	5.161	EPSD	ICGC	3.469	Down-regulation
TK_Src_SrcA_FYN_Y	Q12879	GRIN2A	P06241	FYN	Y1292	P1299L	1299	Missense	distal	7	no	5.278	5.249	EPSD	ICGC	3.469	Down-regulation
TK_Src_SrcA_FYN_Y	Q12879	GRIN2A	P06241	FYN	Y1292	D1297V	1297	Missense	distal	5	no	5.278	5.019	EPSD	ICGC;COSMIC	3.469	Down-regulation
TK_Src_SrcA_FYN_Y	Q12879	GRIN2A	P06241	FYN	Y1325	L1320R	1320	Missense	distal	-5	no	3.797	4.466	EPSD;PhosphoSitePlus	ICGC;COSMIC	3.469	Up-regulation
TK_Src_SrcA_FYN_Y	Q12879	GRIN2A	P06241	FYN	Y1325	P1332S	1332	Missense	distal	7	no	3.797	3.795	EPSD;PhosphoSitePlus	ICGC	3.469	Down-regulation
TK_Src_SrcA_FYN_Y	Q96J02	ITCH	P06241	FYN	Y375	Y376C	376	Missense	proximal	1	no	4.683	2.448	EPSD	ICGC;COSMIC	3.469	Loss
TK_Src_SrcA_FYN_Y	Q96J02	ITCH	P06241	FYN	Y495	N500S	500	Missense	distal	5	no	3.984	3.765	EPSD	ICGC	3.469	Down-regulation
TK_Src_SrcA_FYN_Y	Q96J02	ITCH	P06241	FYN	Y495	V497L	497	Missense	proximal	2	no	3.984	3.899	EPSD	ICGC	3.469	Down-regulation
TK_Src_SrcA_FYN_Y	Q96J02	ITCH	P06241	FYN	Y589	D588G	588	Missense	proximal	-1	no	3.629	3.653	EPSD	ICGC;COSMIC	3.469	Up-regulation
TK_Src_SrcA_FYN_Y	P30419	NMT1	P06241	FYN	Y327	E331A	331	Missense	distal	4	no	4.071	3.955	EPSD	ICGC	3.469	Down-regulation
TK_Src_SrcA_FYN_Y	P30419	NMT1	P06241	FYN	Y327	E331D	331	Missense	distal	4	no	4.071	3.805	EPSD	ICGC;COSMIC	3.469	Down-regulation
TK_Src_SrcA_FYN_Y	P30419	NMT1	P06241	FYN	Y327	K334N	334	Missense	distal	7	no	4.071	4.100	EPSD	ICGC	3.469	Up-regulation
TK_Src_SrcA_FYN_Y	P06127	CD5	P06241	FYN	Y51	L48P	48	Missense	distal	-3	no	3.899	4.770	EPSD	ICGC;COSMIC	3.469	Up-regulation
TK_Src_SrcA_FYN_Y	P06127	CD5	P06241	FYN	Y51	W56C	56	Missense	distal	5	no	3.899	4.249	EPSD	ICGC	3.469	Up-regulation
TK_Src_SrcA_FYN_Y	P06127	CD5	P06241	FYN	Y51	G55R	55	Missense	distal	4	no	3.899	3.991	EPSD	ICGC;COSMIC;CCLE	3.469	Up-regulation
TK_Src_SrcA_FYN_Y	P06127	CD5	P06241	FYN	Y51	H57R	57	Missense	distal	6	no	3.899	3.638	EPSD	ICGC	3.469	Down-regulation
TK_Src_SrcA_FYN_Y	P06127	CD5	P06241	FYN	Y487	D484N	484	Missense	distal	-3	no	3.992	3.429	EPSD;PhosphoSitePlus	ICGC;COSMIC	3.469	Loss
TK_Src_SrcA_FYN_Y	P16885	PLCG2	P06241	FYN	Y753	D748Y	748	Missense	distal	-5	no	7.406	6.037	PhosphoSitePlus;EPSD	ICGC;COSMIC	3.469	Down-regulation
TK_Src_SrcA_FYN_Y	P16885	PLCG2	P06241	FYN	Y759	P762H	762	Missense	distal	3	no	3.649	2.374	EPSD;PhosphoSitePlus	ICGC;COSMIC	3.469	Loss
TK_Src_SrcA_FYN_Y	P16885	PLCG2	P06241	FYN	Y778	V774M	774	Missense	distal	-4	no	7.017	7.858	EPSD	ICGC;COSMIC	3.469	Up-regulation
TK_Src_SrcA_FYN_Y	P16885	PLCG2	P06241	FYN	Y778	A782S	782	Missense	distal	4	no	7.017	7.082	EPSD	ICGC	3.469	Up-regulation
TK_Src_SrcA_FYN_Y	P16885	PLCG2	P06241	FYN	Y778	R784L	784	Missense	distal	6	no	7.017	7.282	EPSD	ICGC;COSMIC	3.469	Up-regulation
TK_Src_SrcA_FYN_Y	P16885	PLCG2	P06241	FYN	Y936	C937F	937	Missense	proximal	1	no	3.104	3.759	EPSD	ICGC	3.469	Gain
TK_Src_SrcA_FYN_Y	P16885	PLCG2	P06241	FYN	Y1048	P1052L	1052	Missense	distal	4	no	6.165	6.008	EPSD	ICGC	3.469	Down-regulation
TK_Src_SrcA_FYN_Y	P00519	ABL1	P06241	FYN	Y70	F72V	72	Missense	proximal	2	no	3.491	3.677	EPSD;PhosphoSitePlus	ICGC;COSMIC	3.469	Up-regulation
TK_Src_SrcA_FYN_Y	P00519	ABL1	P06241	FYN	Y70	D71N	71	Missense	proximal	1	no	3.491	2.620	EPSD;PhosphoSitePlus	ICGC;COSMIC	3.469	Loss
TK_Src_SrcA_FYN_Y	P00519	ABL1	P06241	FYN	Y70	Y70H	70	Missense	central	0	yes	3.491	0.000	EPSD;PhosphoSitePlus	ICGC;COSMIC	3.469	Loss
TK_Src_SrcA_FYN_Y	P00519	ABL1	P06241	FYN	Y70	S75R	75	Missense	distal	5	no	3.491	3.666	EPSD;PhosphoSitePlus	ICGC;COSMIC	3.469	Up-regulation
TK_Src_SrcA_FYN_Y	P00519	ABL1	P06241	FYN	Y70	V67F	67	Missense	distal	-3	no	3.491	1.646	EPSD;PhosphoSitePlus	ICGC;COSMIC	3.469	Loss
TK_Src_SrcA_FYN_Y	P00519	ABL1	P06241	FYN	Y115	V111L	111	Missense	distal	-4	no	3.603	3.345	EPSD;PhosphoSitePlus	ICGC;COSMIC	3.469	Loss
TK_Src_SrcA_FYN_Y	P00519	ABL1	P06241	FYN	Y115	V119F	119	Missense	distal	4	no	3.603	3.556	EPSD;PhosphoSitePlus	ICGC	3.469	Down-regulation
TK_Src_SrcA_FYN_Y	P00519	ABL1	P06241	FYN	Y128	R134L	134	Missense	distal	6	no	4.824	5.089	EPSD;PhosphoSitePlus	ICGC;COSMIC	3.469	Up-regulation
TK_Src_SrcA_FYN_Y	P00519	ABL1	P06241	FYN	Y128	P131S	131	Missense	distal	3	no	4.824	4.233	EPSD;PhosphoSitePlus	ICGC;GDSC	3.469	Down-regulation
TK_Src_SrcA_FYN_Y	P00519	ABL1	P06241	FYN	Y139	G144W	144	Missense	distal	5	no	6.772	6.171	EPSD;PhosphoSitePlus	ICGC	3.469	Down-regulation
TK_Src_SrcA_FYN_Y	P00519	ABL1	P06241	FYN	Y139	R134L	134	Missense	distal	-5	no	6.772	6.104	EPSD;PhosphoSitePlus	ICGC;COSMIC	3.469	Down-regulation
TK_Src_SrcA_FYN_Y	P00519	ABL1	P06241	FYN	Y139	G144R	144	Missense	distal	5	no	6.772	7.030	EPSD;PhosphoSitePlus	ICGC	3.469	Up-regulation
TK_Src_SrcA_FYN_Y	P00519	ABL1	P06241	FYN	Y172	G169W	169	Missense	distal	-3	no	8.367	4.110	EPSD;PhosphoSitePlus	ICGC;COSMIC	3.469	Down-regulation
TK_Src_SrcA_FYN_Y	P00519	ABL1	P06241	FYN	Y172	R170G	170	Missense	proximal	-2	no	8.367	9.484	EPSD;PhosphoSitePlus	ICGC;COSMIC	3.469	Up-regulation
TK_Src_SrcA_FYN_Y	P00519	ABL1	P06241	FYN	Y185	E189G	189	Missense	distal	4	no	4.806	4.581	EPSD;PhosphoSitePlus	ICGC;COSMIC	3.469	Down-regulation
TK_Src_SrcA_FYN_Y	P00519	ABL1	P06241	FYN	Y185	V186I	186	Missense	proximal	1	no	4.806	4.711	EPSD;PhosphoSitePlus	ICGC;COSMIC	3.469	Down-regulation
TK_Src_SrcA_FYN_Y	P00519	ABL1	P06241	FYN	Y215	P216L	216	Missense	proximal	1	no	4.580	4.888	EPSD;PhosphoSitePlus	ICGC	3.469	Up-regulation
TK_Src_SrcA_FYN_Y	P00519	ABL1	P06241	FYN	Y226	Y232C	232	Missense	distal	6	no	3.205	3.611	EPSD;PhosphoSitePlus	ICGC;COSMIC	3.469	Gain
TK_Src_SrcA_FYN_Y	P00519	ABL1	P06241	FYN	Y257	Y253N	253	Missense	distal	-4	no	1.864	4.362	EPSD	ICGC;COSMIC	3.469	Gain
TK_Src_SrcA_FYN_Y	O75051	PLXNA2	P06241	FYN	Y1605	Y1605H	1605	Missense	central	0	yes	5.922	0.000	PhosphoSitePlus;EPSD	ICGC;COSMIC	3.469	Loss
TK_Src_SrcA_FYN_Y	O75051	PLXNA2	P06241	FYN	Y1677	E1675K	1675	Missense	proximal	-2	no	5.530	4.900	EPSD;PhosphoSitePlus	ICGC;COSMIC	3.469	Down-regulation
TK_Src_SrcA_FYN_Y	O75051	PLXNA2	P06241	FYN	Y1677	L1681I	1681	Missense	distal	4	no	5.530	5.339	EPSD;PhosphoSitePlus	ICGC;COSMIC	3.469	Down-regulation
TK_Src_SrcA_FYN_Y	Q01628	IFITM3	P06241	FYN	Y20	K24Q	24	Missense	distal	4	no	4.247	4.141	PhosphoSitePlus	ICGC	3.469	Down-regulation
TK_Src_SrcA_FYN_Y	Q01628	IFITM3	P06241	FYN	Y20	E25G	25	Missense	distal	5	no	4.247	4.008	PhosphoSitePlus	ICGC;COSMIC	3.469	Down-regulation
TK_Src_SrcA_FYN_Y	Q03135	CAV1	P06241	FYN	Y14	V7L	7	Missense	distal	-7	no	5.566	5.052	PhosphoSitePlus	ICGC	3.469	Down-regulation
TK_Src_SrcA_FYN_Y	Q03135	CAV1	P06241	FYN	Y14	E10D	10	Missense	distal	-4	no	5.566	6.426	PhosphoSitePlus	ICGC	3.469	Up-regulation
TK_Src_SrcA_FYN_Y	Q03135	CAV1	P06241	FYN	Y14	V16I	16	Missense	proximal	2	no	5.566	5.419	PhosphoSitePlus	ICGC;COSMIC	3.469	Down-regulation
TK_Src_SrcA_FYN_Y	Q03135	CAV1	P06241	FYN	Y14	R19L	19	Missense	distal	5	no	5.566	5.064	PhosphoSitePlus	ICGC;COSMIC	3.469	Down-regulation
TK_Src_SrcA_FYN_Y	Q03135	CAV1	P06241	FYN	Y25	R19L	19	Missense	distal	-6	no	3.942	3.330	EPSD	ICGC;COSMIC	3.469	Loss
TK_Src_SrcA_FYN_Y	Q03135	CAV1	P06241	FYN	Y42	A44T	44	Missense	proximal	2	no	4.473	4.815	EPSD	ICGC;COSMIC	3.469	Up-regulation
TK_Src_SrcA_FYN_Y	Q03135	CAV1	P06241	FYN	Y42	E35D	35	Missense	distal	-7	no	4.473	4.103	EPSD	ICGC	3.469	Down-regulation
TK_Src_SrcA_FYN_Y	P52757	CHN2	P06241	FYN	Y55	R52C	52	Missense	distal	-3	no	3.943	1.556	EPSD	ICGC	3.469	Loss
TK_Src_SrcA_FYN_Y	P52757	CHN2	P06241	FYN	Y55	P53L	53	Missense	proximal	-2	no	3.943	3.360	EPSD	ICGC	3.469	Loss
TK_Src_SrcA_FYN_Y	P11274	BCR	P06241	FYN	Y177	F182L	182	Missense	distal	5	no	7.039	6.809	PhosphoSitePlus	ICGC;COSMIC	3.469	Down-regulation
TK_Src_SrcA_FYN_Y	P11274	BCR	P06241	FYN	Y231	A226T	226	Missense	distal	-5	no	2.793	3.709	EPSD	ICGC	3.469	Gain
TK_Src_SrcA_FYN_Y	P11274	BCR	P06241	FYN	Y360	P355T	355	Missense	distal	-5	no	2.876	3.588	EPSD	ICGC;COSMIC	3.469	Gain
TK_Src_SrcA_FYN_Y	P11274	BCR	P06241	FYN	Y360	R361S	361	Missense	proximal	1	no	2.876	3.881	EPSD	ICGC;COSMIC	3.469	Gain
TK_Src_SrcA_FYN_Y	P11274	BCR	P06241	FYN	Y455	R448L	448	Missense	distal	-7	no	5.834	4.649	EPSD	ICGC	3.469	Down-regulation
TK_Src_SrcA_FYN_Y	P11274	BCR	P06241	FYN	Y910	V917I	917	Missense	distal	7	no	4.120	4.109	EPSD	ICGC;COSMIC	3.469	Down-regulation
TK_Src_SrcA_FYN_Y	P11274	BCR	P06241	FYN	Y910	V915G	915	Missense	distal	5	no	4.120	4.301	EPSD	ICGC;COSMIC	3.469	Up-regulation
TK_Src_SrcA_FYN_Y	P11274	BCR	P06241	FYN	Y910	Y910C	910	Missense	central	0	yes	4.120	0.000	EPSD	ICGC;COSMIC	3.469	Loss
TK_Src_SrcA_FYN_Y	P11274	BCR	P06241	FYN	Y910	G911V	911	Missense	proximal	1	no	4.120	2.604	EPSD	ICGC	3.469	Loss
TK_Src_SrcA_FYN_Y	P11274	BCR	P06241	FYN	Y1089	T1096A	1096	Missense	distal	7	no	3.515	3.526	EPSD	ICGC;COSMIC;GDSC	3.469	Up-regulation
TK_Src_SrcA_FYN_Y	P11274	BCR	P06241	FYN	Y1089	M1083T	1083	Missense	distal	-6	no	3.515	4.134	EPSD	ICGC;COSMIC	3.469	Up-regulation
TK_Src_SrcA_FYN_Y	Q9NWQ8	PAG1	P06241	FYN	Y317	P323H	323	Missense	distal	6	no	5.123	5.524	PhosphoSitePlus	ICGC;COSMIC	3.469	Up-regulation
TK_Src_SrcA_FYN_Y	P07766	CD3E	P06241	FYN	Y188	P184L	184	Missense	distal	-4	no	5.331	5.135	PhosphoSitePlus;EPSD	ICGC;COSMIC	3.469	Down-regulation
TK_Src_SrcA_FYN_Y	Q13322	GRB10	P06241	FYN	Y67	A61T	61	Missense	distal	-6	no	2.962	3.528	PhosphoSitePlus	ICGC;COSMIC	3.469	Gain
TK_Src_SrcA_FYN_Y	Q86WV1	SKAP1	P06241	FYN	Y219	P218S	218	Missense	proximal	-1	no	4.627	2.956	EPSD	ICGC	3.469	Loss
TK_Src_SrcA_FYN_Y	Q86WV1	SKAP1	P06241	FYN	Y232	D234Y	234	Missense	proximal	2	no	7.822	6.898	PhosphoSitePlus;EPSD	ICGC;COSMIC	3.469	Down-regulation
TK_Src_SrcA_FYN_Y	Q86WV1	SKAP1	P06241	FYN	Y232	D234N	234	Missense	proximal	2	no	7.822	7.940	PhosphoSitePlus;EPSD	ICGC	3.469	Up-regulation
TK_Src_SrcA_FYN_Y	Q86WV1	SKAP1	P06241	FYN	Y295	A296D	296	Missense	proximal	1	no	2.744	4.166	EPSD;PhosphoSitePlus	ICGC	3.469	Gain
TK_Src_SrcA_FYN_Y	P14923	JUP	P06241	FYN	Y550	T546I	546	Missense	distal	-4	no	3.818	2.646	EPSD;PhosphoSitePlus	ICGC	3.469	Loss
TK_Src_SrcA_FYN_Y	P14923	JUP	P06241	FYN	Y550	Q547H	547	Missense	distal	-3	no	3.818	3.693	EPSD;PhosphoSitePlus	ICGC	3.469	Down-regulation
TK_Src_SrcA_FYN_Y	Q14194	CRMP1	P06241	FYN	Y32	Y32H	32	Missense	central	0	yes	5.405	0.000	EPSD	ICGC;COSMIC	3.469	Loss
TK_Src_SrcA_FYN_Y	Q14194	CRMP1	P06241	FYN	Y32	E38K	38	Missense	distal	6	no	5.405	5.138	EPSD	ICGC;COSMIC	3.469	Down-regulation
TK_Src_SrcA_FYN_Y	Q14194	CRMP1	P06241	FYN	Y32	A33D	33	Missense	proximal	1	no	5.405	6.827	EPSD	ICGC	3.469	Up-regulation
TK_Src_SrcA_FYN_Y	Q14194	CRMP1	P06241	FYN	Y32	Y32F	32	Missense	central	0	yes	5.405	0.000	EPSD	ICGC;COSMIC	3.469	Loss
TK_Src_SrcA_FYN_Y	Q14194	CRMP1	P06241	FYN	Y32	Q29H	29	Missense	distal	-3	no	5.405	5.280	EPSD	ICGC;COSMIC	3.469	Down-regulation
TK_Src_SrcA_FYN_Y	Q14194	CRMP1	P06241	FYN	Y32	I25V	25	Missense	distal	-7	no	5.405	6.613	EPSD	ICGC;COSMIC	3.469	Up-regulation
TK_Src_SrcA_FYN_Y	Q14194	CRMP1	P06241	FYN	Y32	S30F	30	Missense	proximal	-2	no	5.405	4.953	EPSD	ICGC;COSMIC	3.469	Down-regulation
TK_Src_SrcA_FYN_Y	Q14194	CRMP1	P06241	FYN	Y32	D27N	27	Missense	distal	-5	no	5.405	5.022	EPSD	ICGC;COSMIC	3.469	Down-regulation
TK_Src_SrcA_FYN_Y	Q14524	SCN5A	P06241	FYN	Y1494	E1489D	1489	Missense	distal	-5	no	3.435	3.512	PhosphoSitePlus;EPSD	ICGC;COSMIC	3.469	Gain
TK_Src_SrcA_FYN_Y	Q14524	SCN5A	P06241	FYN	Y1495	E1489V	1489	Missense	distal	-6	no	6.999	6.625	EPSD;PhosphoSitePlus	ICGC;COSMIC	3.469	Down-regulation
TK_Src_SrcA_FYN_Y	Q14524	SCN5A	P06241	FYN	Y1495	E1489D	1489	Missense	distal	-6	no	6.999	7.616	EPSD;PhosphoSitePlus	ICGC;COSMIC	3.469	Up-regulation
TK_Src_SrcA_FYN_Y	Q9UIW2	PLXNA1	P06241	FYN	Y159	H154N	154	Missense	distal	-5	no	3.743	4.317	EPSD	ICGC;COSMIC	3.469	Up-regulation
TK_Src_SrcA_FYN_Y	Q9UIW2	PLXNA1	P06241	FYN	Y1097	M1102I	1102	Missense	distal	5	no	4.910	4.650	EPSD	ICGC;COSMIC	3.469	Down-regulation
TK_Src_SrcA_FYN_Y	Q9UIW2	PLXNA1	P06241	FYN	Y1486	T1481M	1481	Missense	distal	-5	no	3.750	3.038	EPSD	ICGC;COSMIC;CCLE	3.469	Loss
TK_Src_SrcA_FYN_Y	Q9UIW2	PLXNA1	P06241	FYN	Y1608	T1605M	1605	Missense	distal	-3	no	4.852	3.720	EPSD;PhosphoSitePlus	ICGC;COSMIC	3.469	Down-regulation
TK_Src_SrcA_FYN_Y	P11137	MAP2	P06241	FYN	Y50	G47R	47	Missense	distal	-3	no	6.379	5.144	EPSD;PhosphoSitePlus	ICGC;COSMIC	3.469	Down-regulation
TK_Src_SrcA_FYN_Y	P11137	MAP2	P06241	FYN	Y50	E55K	55	Missense	distal	5	no	6.379	6.646	EPSD;PhosphoSitePlus	ICGC;COSMIC	3.469	Up-regulation
TK_Src_SrcA_FYN_Y	P11137	MAP2	P06241	FYN	Y67	G74E	74	Missense	distal	7	no	5.132	5.178	PhosphoSitePlus;EPSD	ICGC;COSMIC	3.469	Up-regulation
TK_Src_SrcA_FYN_Y	P51812	RPS6KA3	P06241	FYN	Y483	K480N	480	Missense	distal	-3	no	4.740	5.419	EPSD;PhosphoSitePlus	ICGC;COSMIC	3.469	Up-regulation
TK_Src_SrcA_FYN_Y	P51812	RPS6KA3	P06241	FYN	Y529	A532E	532	Missense	distal	3	no	4.478	4.841	PhosphoSitePlus;EPSD	ICGC	3.469	Up-regulation
TK_Src_SrcA_FYN_Y	P51812	RPS6KA3	P06241	FYN	Y529	Y529C	529	Missense	central	0	yes	4.478	0.000	PhosphoSitePlus;EPSD	ICGC;COSMIC	3.469	Loss
TK_Src_SrcA_FYN_Y	P51812	RPS6KA3	P06241	FYN	Y707	N713S	713	Missense	distal	6	no	7.301	7.160	EPSD;PhosphoSitePlus	ICGC;COSMIC	3.469	Down-regulation
TK_Src_SrcA_FYN_Y	Q14247	CTTN	P06241	FYN	Y162	D167N	167	Missense	distal	5	no	3.391	3.614	EPSD	ICGC;COSMIC;GDSC;CCLE	3.469	Gain
TK_Src_SrcA_FYN_Y	Q14247	CTTN	P06241	FYN	Y302	G305V	305	Missense	distal	3	no	3.114	3.819	EPSD	ICGC	3.469	Gain
TK_Src_SrcA_FYN_Y	Q14247	CTTN	P06241	FYN	Y310	G305V	305	Missense	distal	-5	no	3.754	4.199	EPSD	ICGC	3.469	Up-regulation
TK_Src_SrcA_FYN_Y	Q14247	CTTN	P06241	FYN	Y310	G307S	307	Missense	distal	-3	no	3.754	3.064	EPSD	ICGC;COSMIC	3.469	Loss
TK_Src_SrcA_FYN_Y	Q14247	CTTN	P06241	FYN	Y310	G311A	311	Missense	proximal	1	no	3.754	2.182	EPSD	ICGC;COSMIC	3.469	Loss
TK_Src_SrcA_FYN_Y	Q14247	CTTN	P06241	FYN	Y310	K309R	309	Missense	proximal	-1	no	3.754	2.367	EPSD	ICGC;COSMIC	3.469	Loss
TK_Src_SrcA_FYN_Y	Q14247	CTTN	P06241	FYN	Y310	G311W	311	Missense	proximal	1	no	3.754	-0.310	EPSD	ICGC;COSMIC	3.469	Loss
TK_Src_SrcA_FYN_Y	Q14247	CTTN	P06241	FYN	Y421	A424V	424	Missense	distal	3	no	3.197	4.628	EPSD;PhosphoSitePlus	ICGC;COSMIC;GDSC	3.469	Gain
TK_Src_SrcA_FYN_Y	Q14247	CTTN	P06241	FYN	Y446	A450G	450	Missense	distal	4	no	6.372	6.262	EPSD;PhosphoSitePlus	ICGC;COSMIC	3.469	Down-regulation
TK_Src_SrcA_FYN_Y	Q14247	CTTN	P06241	FYN	Y446	T440M	440	Missense	distal	-6	no	6.372	5.752	EPSD;PhosphoSitePlus	ICGC	3.469	Down-regulation
TK_Src_SrcA_FYN_Y	Q14247	CTTN	P06241	FYN	Y446	E441D	441	Missense	distal	-5	no	6.372	6.449	EPSD;PhosphoSitePlus	ICGC	3.469	Up-regulation
TK_Src_SrcA_FYN_Y	Q14247	CTTN	P06241	FYN	Y446	A450V	450	Missense	distal	4	no	6.372	6.322	EPSD;PhosphoSitePlus	ICGC;COSMIC	3.469	Down-regulation
TK_Src_SrcA_FYN_Y	Q14247	CTTN	P06241	FYN	Y464	A463P	463	Missense	proximal	-1	no	3.140	4.427	EPSD	ICGC;COSMIC	3.469	Gain
TK_Src_SrcA_FYN_Y	Q14247	CTTN	P06241	FYN	Y470	A463P	463	Missense	distal	-7	no	4.928	5.563	EPSD;PhosphoSitePlus	ICGC;COSMIC	3.469	Up-regulation
TK_Src_SrcA_FYN_Y	Q14247	CTTN	P06241	FYN	Y470	P476S	476	Missense	distal	6	no	4.928	4.890	EPSD;PhosphoSitePlus	ICGC;COSMIC	3.469	Down-regulation
TK_Src_SrcA_FYN_Y	Q14247	CTTN	P06241	FYN	Y486	D483N	483	Missense	distal	-3	no	4.455	3.892	PhosphoSitePlus;EPSD	ICGC;COSMIC	3.469	Down-regulation
TK_Src_SrcA_FYN_Y	Q14247	CTTN	P06241	FYN	Y486	D487N	487	Missense	proximal	1	no	4.455	3.584	PhosphoSitePlus;EPSD	ICGC;COSMIC;GDSC	3.469	Down-regulation
TK_Src_SrcA_FYN_Y	Q14247	CTTN	P06241	FYN	Y486	P480A	480	Missense	distal	-6	no	4.455	4.627	PhosphoSitePlus;EPSD	ICGC;COSMIC	3.469	Up-regulation
TK_Src_SrcA_FYN_Y	Q14247	CTTN	P06241	FYN	Y486	D492Y	492	Missense	distal	6	no	4.455	4.622	PhosphoSitePlus;EPSD	ICGC;COSMIC	3.469	Up-regulation
TK_Src_SrcA_FYN_Y	Q14247	CTTN	P06241	FYN	Y486	D492H	492	Missense	distal	6	no	4.455	4.587	PhosphoSitePlus;EPSD	ICGC;COSMIC	3.469	Up-regulation
TK_Src_SrcA_FYN_Y	Q14247	CTTN	P06241	FYN	Y486	P480S	480	Missense	distal	-6	no	4.455	5.208	PhosphoSitePlus;EPSD	ICGC;COSMIC	3.469	Up-regulation
TK_Src_SrcA_FYN_Y	Q14247	CTTN	P06241	FYN	Y486	L493M	493	Missense	distal	7	no	4.455	4.488	PhosphoSitePlus;EPSD	ICGC;COSMIC	3.469	Up-regulation
TK_Src_SrcA_FYN_Y	O75886	STAM2	P06241	FYN	Y192	K189E	189	Missense	distal	-3	no	4.574	5.359	EPSD	ICGC;COSMIC	3.469	Up-regulation
TK_Src_SrcA_FYN_Y	O75886	STAM2	P06241	FYN	Y291	P287H	287	Missense	distal	-4	no	8.221	8.478	EPSD;PhosphoSitePlus	ICGC	3.469	Up-regulation
TK_Src_SrcA_FYN_Y	O75886	STAM2	P06241	FYN	Y291	P289H	289	Missense	proximal	-2	no	8.221	7.550	EPSD;PhosphoSitePlus	ICGC	3.469	Down-regulation
TK_Src_SrcA_FYN_Y	O75886	STAM2	P06241	FYN	Y361	A357D	357	Missense	distal	-4	no	2.711	4.888	EPSD	ICGC	3.469	Gain
TK_Src_SrcA_FYN_Y	O75886	STAM2	P06241	FYN	Y371	V370A	370	Missense	proximal	-1	no	8.745	6.069	PhosphoSitePlus;EPSD	ICGC	3.469	Down-regulation
TK_Src_SrcA_FYN_Y	O75886	STAM2	P06241	FYN	Y371	Y371H	371	Missense	central	0	yes	8.745	0.000	PhosphoSitePlus;EPSD	ICGC;COSMIC	3.469	Loss
TK_Src_SrcA_FYN_Y	O75886	STAM2	P06241	FYN	Y371	P369Q	369	Missense	proximal	-2	no	8.745	8.484	PhosphoSitePlus;EPSD	ICGC;COSMIC	3.469	Down-regulation
TK_Src_SrcA_FYN_Y	O75886	STAM2	P06241	FYN	Y374	V370A	370	Missense	distal	-4	no	4.897	4.738	EPSD;PhosphoSitePlus	ICGC	3.469	Down-regulation
TK_Src_SrcA_FYN_Y	O75886	STAM2	P06241	FYN	Y374	Y371H	371	Missense	distal	-3	no	4.897	4.583	EPSD;PhosphoSitePlus	ICGC;COSMIC	3.469	Down-regulation
TK_Src_SrcA_FYN_Y	O75886	STAM2	P06241	FYN	Y374	P369Q	369	Missense	distal	-5	no	4.897	5.276	EPSD;PhosphoSitePlus	ICGC;COSMIC	3.469	Up-regulation
TK_Src_SrcA_FYN_Y	P06241	FYN	P06241	FYN	Y28	Q24K	24	Missense	distal	-4	no	4.699	3.897	EPSD;PhosphoSitePlus	ICGC	3.469	Down-regulation
TK_Src_SrcA_FYN_Y	P06241	FYN	P06241	FYN	Y28	S25R	25	Missense	distal	-3	no	4.699	4.153	EPSD;PhosphoSitePlus	ICGC	3.469	Down-regulation
TK_Src_SrcA_FYN_Y	P06241	FYN	P06241	FYN	Y39	P40L	40	Missense	proximal	1	no	3.239	3.546	EPSD;PhosphoSitePlus	ICGC;COSMIC	3.469	Gain
TK_Src_SrcA_FYN_Y	P06241	FYN	P06241	FYN	Y39	P36T	36	Missense	distal	-3	no	3.239	4.501	EPSD;PhosphoSitePlus	ICGC;COSMIC	3.469	Gain
TK_Src_SrcA_FYN_Y	P06241	FYN	P06241	FYN	Y185	R190H	190	Missense	distal	5	no	6.198	5.714	EPSD;PhosphoSitePlus	ICGC;COSMIC	3.469	Down-regulation
TK_Src_SrcA_FYN_Y	Q13291	SLAMF1	P06241	FYN	Y281	A282D	282	Missense	proximal	1	no	4.588	6.010	PhosphoSitePlus;EPSD	ICGC	3.469	Up-regulation
TK_Src_SrcA_FYN_Y	Q13291	SLAMF1	P06241	FYN	Y281	A282V	282	Missense	proximal	1	no	4.588	4.644	PhosphoSitePlus;EPSD	ICGC;COSMIC	3.469	Up-regulation
TK_Src_SrcA_FYN_Y	Q13291	SLAMF1	P06241	FYN	Y281	S277R	277	Missense	distal	-4	no	4.588	4.937	PhosphoSitePlus;EPSD	ICGC	3.469	Up-regulation
TK_Src_SrcA_FYN_Y	Q13291	SLAMF1	P06241	FYN	Y307	A310S	310	Missense	distal	3	no	2.960	3.736	EPSD;PhosphoSitePlus	ICGC;COSMIC	3.469	Gain
TK_Src_SrcA_FYN_Y	P54646	PRKAA2	P06241	FYN	Y179	A180S	180	Missense	proximal	1	no	2.687	3.500	EPSD	ICGC	3.469	Gain
TK_Src_SrcA_FYN_Y	Q16539	MAPK14	P06241	FYN	Y35	V38L	38	Missense	distal	3	no	4.318	3.719	EPSD	ICGC;COSMIC	3.469	Down-regulation
TK_Src_SrcA_FYN_Y	Q16539	MAPK14	P06241	FYN	Y323	D321N	321	Missense	proximal	-2	no	4.394	4.755	PhosphoSitePlus	ICGC	3.469	Up-regulation
TK_Src_SrcA_FYN_Y	Q8TDQ1	CD300LF	P06241	FYN	Y263	P261L	261	Missense	proximal	-2	no	3.519	2.936	PhosphoSitePlus;EPSD	ICGC	3.469	Loss
TK_Src_SrcA_FYN_Y	Q8TDQ1	CD300LF	P06241	FYN	Y263	M266I	266	Missense	distal	3	no	3.519	3.552	PhosphoSitePlus;EPSD	ICGC;COSMIC	3.469	Up-regulation
TK_Src_SrcA_FYN_Y	Q8TDQ1	CD300LF	P06241	FYN	Y263	S270G	270	Missense	distal	7	no	3.519	3.516	PhosphoSitePlus;EPSD	ICGC;COSMIC	3.469	Down-regulation
TK_Src_SrcA_FYN_Y	O75955	FLOT1	P06241	FYN	Y223	R230H	230	Missense	distal	7	no	4.117	4.059	EPSD	ICGC	3.469	Down-regulation
TK_Src_SrcA_FYN_Y	Q15858	SCN9A	P06241	FYN	Y1481	M1485I	1485	Missense	distal	4	no	4.099	3.756	EPSD;PhosphoSitePlus	ICGC;COSMIC	3.469	Down-regulation
TK_Src_SrcA_FYN_Y	Q15858	SCN9A	P06241	FYN	Y1481	A1484T	1484	Missense	distal	3	no	4.099	4.618	EPSD;PhosphoSitePlus	ICGC	3.469	Up-regulation
TK_Src_SrcA_FYN_Y	Q15858	SCN9A	P06241	FYN	Y1481	T1475K	1475	Missense	distal	-6	no	4.099	4.304	EPSD;PhosphoSitePlus	ICGC	3.469	Up-regulation
TK_Src_SrcA_FYN_Y	Q15858	SCN9A	P06241	FYN	Y1481	M1474L	1474	Missense	distal	-7	no	4.099	3.414	EPSD;PhosphoSitePlus	ICGC;COSMIC	3.469	Loss
TK_Src_SrcA_FYN_Y	Q15858	SCN9A	P06241	FYN	Y1481	M1485T	1485	Missense	distal	4	no	4.099	4.045	EPSD;PhosphoSitePlus	ICGC;COSMIC	3.469	Down-regulation
TK_Src_SrcA_FYN_Y	Q15858	SCN9A	P06241	FYN	Y1482	M1485I	1485	Missense	distal	3	no	7.833	7.866	PhosphoSitePlus;EPSD	ICGC;COSMIC	3.469	Up-regulation
TK_Src_SrcA_FYN_Y	Q15858	SCN9A	P06241	FYN	Y1482	A1484T	1484	Missense	proximal	2	no	7.833	8.176	PhosphoSitePlus;EPSD	ICGC	3.469	Up-regulation
TK_Src_SrcA_FYN_Y	Q15858	SCN9A	P06241	FYN	Y1482	T1475K	1475	Missense	distal	-7	no	7.833	7.220	PhosphoSitePlus;EPSD	ICGC	3.469	Down-regulation
TK_Src_SrcA_FYN_Y	Q15858	SCN9A	P06241	FYN	Y1482	G1489E	1489	Missense	distal	7	no	7.833	7.880	PhosphoSitePlus;EPSD	ICGC	3.469	Up-regulation
TK_Src_SrcA_FYN_Y	Q15858	SCN9A	P06241	FYN	Y1482	M1485T	1485	Missense	distal	3	no	7.833	7.406	PhosphoSitePlus;EPSD	ICGC;COSMIC	3.469	Down-regulation
TK_Src_SrcA_FYN_Y	P22681	CBL	P06241	FYN	Y700	M701L	701	Missense	proximal	1	no	6.283	7.255	PhosphoSitePlus;EPSD	ICGC;COSMIC	3.469	Up-regulation
TK_Src_SrcA_FYN_Y	P22681	CBL	P06241	FYN	Y700	E696D	696	Missense	distal	-4	no	6.283	7.143	PhosphoSitePlus;EPSD	ICGC;COSMIC	3.469	Up-regulation
TK_Src_SrcA_FYN_Y	P22681	CBL	P06241	FYN	Y700	E693D	693	Missense	distal	-7	no	6.283	5.913	PhosphoSitePlus;EPSD	ICGC;COSMIC	3.469	Down-regulation
TK_Src_SrcA_FYN_Y	P22681	CBL	P06241	FYN	Y774	G773E	773	Missense	proximal	-1	no	6.078	7.068	EPSD;PhosphoSitePlus	ICGC	3.469	Up-regulation
TK_Src_SrcA_FYN_Y	Q12913	PTPRJ	P06241	FYN	Y587	A590V	590	Missense	distal	3	no	5.344	6.775	EPSD	ICGC;CCLE	3.469	Up-regulation
TK_Src_SrcA_FYN_Y	Q12913	PTPRJ	P06241	FYN	Y587	D588A	588	Missense	proximal	1	no	5.344	3.923	EPSD	ICGC	3.469	Down-regulation
TK_Src_SrcA_FYN_Y	Q12913	PTPRJ	P06241	FYN	Y1077	V1074G	1074	Missense	distal	-3	no	2.158	3.473	EPSD	ICGC	3.469	Gain
TK_Src_SrcA_FYN_Y	Q12913	PTPRJ	P06241	FYN	Y1094	A1097S	1097	Missense	distal	3	no	3.004	3.780	EPSD	ICGC	3.469	Gain
TK_Src_SrcA_FYN_Y	Q12913	PTPRJ	P06241	FYN	Y1311	T1318S	1318	Missense	distal	7	no	7.089	7.079	EPSD;PhosphoSitePlus	ICGC;COSMIC	3.469	Down-regulation
TK_Src_SrcA_FYN_Y	Q12913	PTPRJ	P06241	FYN	Y1320	T1318S	1318	Missense	proximal	-2	no	4.307	4.177	PhosphoSitePlus;EPSD	ICGC;COSMIC	3.469	Down-regulation
TK_Src_SrcA_FYN_Y	Q14254	FLOT2	P06241	FYN	Y158	K155Q	155	Missense	distal	-3	no	4.732	4.608	EPSD	ICGC;COSMIC	3.469	Down-regulation
TK_Src_SrcA_FYN_Y	P37840	SNCA	P06241	FYN	Y125	P120T	120	Missense	distal	-5	no	5.616	6.328	PhosphoSitePlus	ICGC	3.469	Up-regulation
TK_Src_SrcA_FYN_Y	P37840	SNCA	P06241	FYN	Y136	Q134K	134	Missense	proximal	-2	no	3.961	3.527	EPSD	ICGC;COSMIC	3.469	Down-regulation
TK_Src_SrcA_FYN_Y	P40763	STAT3	P06241	FYN	Y22	M28V	28	Missense	distal	6	no	3.772	3.625	EPSD	ICGC;COSMIC	3.469	Down-regulation
TK_Src_SrcA_FYN_Y	P40763	STAT3	P06241	FYN	Y22	Y22H	22	Missense	central	0	yes	3.772	0.000	EPSD	ICGC;COSMIC	3.469	Loss
TK_Src_SrcA_FYN_Y	P40763	STAT3	P06241	FYN	Y446	G449D	449	Missense	distal	3	no	4.534	3.670	EPSD	ICGC;COSMIC	3.469	Down-regulation
TK_Src_SrcA_FYN_Y	P40763	STAT3	P06241	FYN	Y446	D453E	453	Missense	distal	7	no	4.534	4.578	EPSD	ICGC	3.469	Up-regulation
TK_Src_SrcA_FYN_Y	P40763	STAT3	P06241	FYN	Y446	E442K	442	Missense	distal	-4	no	4.534	3.764	EPSD	ICGC	3.469	Down-regulation
TK_Src_SrcA_FYN_Y	P40763	STAT3	P06241	FYN	Y640	P639Q	639	Missense	proximal	-1	no	4.147	2.591	EPSD	ICGC	3.469	Loss
TK_Src_SrcA_FYN_Y	P40763	STAT3	P06241	FYN	Y640	T641R	641	Missense	proximal	1	no	4.147	3.427	EPSD	ICGC;COSMIC	3.469	Loss
TK_Src_SrcA_FYN_Y	P40763	STAT3	P06241	FYN	Y640	N647Y	647	Missense	distal	7	no	4.147	4.096	EPSD	ICGC;COSMIC	3.469	Down-regulation
TK_Src_SrcA_FYN_Y	P40763	STAT3	P06241	FYN	Y705	A702T	702	Missense	distal	-3	no	6.980	7.412	PhosphoSitePlus	ICGC;COSMIC	3.469	Up-regulation
TK_Src_SrcA_FYN_Y	P12318	FCGR2A	P06241	FYN	Y281	L274P	274	Missense	distal	-7	no	4.017	5.394	EPSD	ICGC;COSMIC	3.469	Up-regulation
TK_Src_SrcA_FYN_Y	P12318	FCGR2A	P06241	FYN	Y281	Y288F	288	Missense	distal	7	no	4.017	4.030	EPSD	ICGC;COSMIC	3.469	Up-regulation
TK_Src_SrcA_FYN_Y	P12318	FCGR2A	P06241	FYN	Y304	D298N	298	Missense	distal	-6	no	6.199	5.356	EPSD	ICGC;COSMIC	3.469	Down-regulation
TK_Src_SrcA_FYN_Y	P12318	FCGR2A	P06241	FYN	Y304	D299N	299	Missense	distal	-5	no	6.199	5.817	EPSD	ICGC;COSMIC	3.469	Down-regulation
TK_Src_SrcA_FYN_Y	P35637	FUS	P06241	FYN	Y468	D470G	470	Missense	proximal	2	no	5.597	4.968	EPSD	ICGC;COSMIC	3.469	Down-regulation
TK_Src_SrcA_FYN_Y	Q06124	PTPN11	P06241	FYN	Y62	D61N	61	Missense	proximal	-1	no	2.729	3.741	EPSD	ICGC;COSMIC	3.469	Gain
TK_Src_SrcA_FYN_Y	Q06124	PTPN11	P06241	FYN	Y62	D61V	61	Missense	proximal	-1	no	2.729	5.321	EPSD	ICGC;COSMIC	3.469	Gain
TK_Src_SrcA_FYN_Y	Q06124	PTPN11	P06241	FYN	Y279	R278K	278	Missense	proximal	-1	no	2.189	3.576	EPSD	ICGC;CCLE	3.469	Gain
TK_Src_SrcA_FYN_Y	Q06124	PTPN11	P06241	FYN	Y304	N308S	308	Missense	distal	4	no	3.867	3.827	EPSD	ICGC;COSMIC	3.469	Down-regulation
TK_Src_SrcA_FYN_Y	Q06124	PTPN11	P06241	FYN	Y304	N306S	306	Missense	proximal	2	no	3.867	2.786	EPSD	ICGC;COSMIC	3.469	Loss
TK_Src_SrcA_FYN_Y	Q06124	PTPN11	P06241	FYN	Y304	A307S	307	Missense	distal	3	no	3.867	4.643	EPSD	ICGC	3.469	Up-regulation
TK_Src_SrcA_FYN_Y	Q06124	PTPN11	P06241	FYN	Y304	V301F	301	Missense	distal	-3	no	3.867	2.022	EPSD	ICGC	3.469	Loss
TK_Src_SrcA_FYN_Y	Q06124	PTPN11	P06241	FYN	Y304	A307E	307	Missense	distal	3	no	3.867	4.230	EPSD	ICGC;COSMIC	3.469	Up-regulation
TK_Src_SrcA_FYN_Y	Q06124	PTPN11	P06241	FYN	Y304	N308T	308	Missense	distal	4	no	3.867	3.821	EPSD	ICGC;COSMIC	3.469	Down-regulation
TK_Src_SrcA_FYN_Y	Q9NZA1	CLIC5	P06241	FYN	Y33	D34N	34	Missense	proximal	1	no	7.553	6.682	PhosphoSitePlus	ICGC;COSMIC	3.469	Down-regulation
TK_Src_SrcA_FYN_Y	Q9NZA1	CLIC5	P06241	FYN	Y33	H37N	37	Missense	distal	4	no	7.553	7.744	PhosphoSitePlus	ICGC	3.469	Up-regulation
TK_Src_SrcA_FYN_Y	Q9NZA1	CLIC5	P06241	FYN	Y33	E27K	27	Missense	distal	-6	no	7.553	7.887	PhosphoSitePlus	ICGC;COSMIC	3.469	Up-regulation
TK_Src_SrcA_FYN_Y	Q9NZA1	CLIC5	P06241	FYN	Y33	E26K	26	Missense	distal	-7	no	7.553	6.517	PhosphoSitePlus	ICGC	3.469	Down-regulation
TK_Src_SrcA_FYN_Y	P35612	ADD2	P06241	FYN	Y377	R384H	384	Missense	distal	7	no	5.069	5.011	EPSD	ICGC;COSMIC	3.469	Down-regulation
TK_Src_SrcA_FYN_Y	P35612	ADD2	P06241	FYN	Y377	R370K	370	Missense	distal	-7	no	5.069	4.068	EPSD	ICGC;COSMIC	3.469	Down-regulation
TK_Src_SrcA_FYN_Y	P35612	ADD2	P06241	FYN	Y489	P492H	492	Missense	distal	3	no	5.617	4.343	PhosphoSitePlus	ICGC;COSMIC	3.469	Down-regulation
TK_Src_SrcA_FYN_Y	P35612	ADD2	P06241	FYN	Y489	D491G	491	Missense	proximal	2	no	5.617	4.988	PhosphoSitePlus	ICGC;COSMIC	3.469	Down-regulation
TK_Src_SrcA_FYN_Y	P35612	ADD2	P06241	FYN	Y489	Q484K	484	Missense	distal	-5	no	5.617	5.935	PhosphoSitePlus	ICGC	3.469	Up-regulation
TK_Src_SrcA_FYN_Y	P35612	ADD2	P06241	FYN	Y489	L496M	496	Missense	distal	7	no	5.617	5.650	PhosphoSitePlus	ICGC;COSMIC	3.469	Up-regulation
TK_Src_SrcA_FYN_Y	P10636	MAPT	P06241	FYN	Y18	A15T	15	Missense	distal	-3	no	7.108	7.540	PhosphoSitePlus	ICGC;COSMIC	3.469	Up-regulation
TK_Src_SrcA_FYN_Y	P10636	MAPT	P06241	FYN	Y18	M11I	11	Missense	distal	-7	no	7.108	5.729	PhosphoSitePlus	ICGC	3.469	Down-regulation
TK_Src_SrcA_FYN_Y	P10636	MAPT	P06241	FYN	Y29	E36D	36	Missense	distal	7	no	5.368	5.325	EPSD	ICGC;COSMIC	3.469	Down-regulation
TK_Src_SrcA_FYN_Y	P10636	MAPT	P06241	FYN	Y29	Q26L	26	Missense	distal	-3	no	5.368	3.982	EPSD	ICGC;COSMIC	3.469	Down-regulation
TK_Src_SrcA_FYN_Y	P10636	MAPT	P06241	FYN	Y29	D34Y	34	Missense	distal	5	no	5.368	5.699	EPSD	ICGC;COSMIC	3.469	Up-regulation
TK_Src_SrcA_FYN_Y	P78352	DLG4	P06241	FYN	Y240	N234S	234	Missense	distal	-6	no	3.201	3.571	EPSD	ICGC;COSMIC	3.469	Gain
TK_Src_SrcA_FYN_Y	P78352	DLG4	P06241	FYN	Y580	R578S	578	Missense	proximal	-2	no	5.614	6.445	EPSD	ICGC	3.469	Up-regulation
TK_Src_SrcA_FYN_Y	P17612	PRKACA	P06241	FYN	Y205	P203H	203	Missense	proximal	-2	no	3.662	2.992	EPSD	ICGC;COSMIC	3.469	Loss
Other_TTK_TTK_ST	Q9Y5T5	USP16	P33981	TTK	S17	P12Q	12	Missense	distal	-5	no	17.545	18.667	EPSD	ICGC;COSMIC	18.469	Gain
Other_TTK_TTK_ST	P33981	TTK	P33981	TTK	S49	V52F	52	Missense	distal	3	no	19.054	14.553	EPSD	ICGC;COSMIC	18.469	Loss
Other_TTK_TTK_ST	P33981	TTK	P33981	TTK	S49	S49A	49	Missense	central	0	yes	19.054	0.000	EPSD	ICGC;COSMIC	18.469	Loss
Other_TTK_TTK_ST	P33981	TTK	P33981	TTK	S80	D81Y	81	Missense	proximal	1	no	24.126	24.116	EPSD;PhosphoSitePlus	ICGC	18.469	Down-regulation
Other_TTK_TTK_ST	P33981	TTK	P33981	TTK	S80	N75S	75	Missense	distal	-5	no	24.126	22.085	EPSD;PhosphoSitePlus	ICGC;COSMIC	18.469	Down-regulation
Other_TTK_TTK_ST	P33981	TTK	P33981	TTK	S80	S76G	76	Missense	distal	-4	no	24.126	24.095	EPSD;PhosphoSitePlus	ICGC;COSMIC;GDSC;CCLE	18.469	Down-regulation
Other_TTK_TTK_ST	P33981	TTK	P33981	TTK	T210	A211S	211	Missense	proximal	1	no	20.797	20.803	EPSD	ICGC	18.469	Up-regulation
Other_TTK_TTK_ST	P33981	TTK	P33981	TTK	T210	A211D	211	Missense	proximal	1	no	20.797	20.807	EPSD	ICGC;COSMIC	18.469	Up-regulation
Other_TTK_TTK_ST	P33981	TTK	P33981	TTK	T288	P294H	294	Missense	distal	6	no	20.915	18.743	EPSD;PhosphoSitePlus	ICGC;COSMIC	18.469	Down-regulation
Other_TTK_TTK_ST	P33981	TTK	P33981	TTK	T288	D283N	283	Missense	distal	-5	no	20.915	22.481	EPSD;PhosphoSitePlus	ICGC	18.469	Up-regulation
Other_TTK_TTK_ST	P33981	TTK	P33981	TTK	T301	D308Y	308	Missense	distal	7	no	21.400	21.331	EPSD	ICGC	18.469	Down-regulation
Other_TTK_TTK_ST	P33981	TTK	P33981	TTK	T301	R299I	299	Missense	proximal	-2	no	21.400	21.897	EPSD	ICGC;COSMIC	18.469	Up-regulation
Other_TTK_TTK_ST	P33981	TTK	P33981	TTK	T301	P294H	294	Missense	distal	-7	no	21.400	23.525	EPSD	ICGC;COSMIC	18.469	Up-regulation
Other_TTK_TTK_ST	P33981	TTK	P33981	TTK	T360	I354V	354	Missense	distal	-6	no	20.869	20.960	EPSD;PhosphoSitePlus	ICGC;COSMIC	18.469	Up-regulation
Other_TTK_TTK_ST	P33981	TTK	P33981	TTK	S382	Q386R	386	Missense	distal	4	no	19.034	18.610	EPSD	ICGC;COSMIC	18.469	Down-regulation
Other_TTK_TTK_ST	P33981	TTK	P33981	TTK	S582	I585V	585	Missense	distal	3	no	20.360	18.652	EPSD;PhosphoSitePlus	ICGC;COSMIC	18.469	Down-regulation
Other_TTK_TTK_ST	P33981	TTK	P33981	TTK	S582	I585T	585	Missense	distal	3	no	20.360	15.580	EPSD;PhosphoSitePlus	ICGC;COSMIC	18.469	Loss
Other_TTK_TTK_ST	P33981	TTK	P33981	TTK	T675	T675A	675	Missense	central	0	yes	23.394	0.000	EPSD;PhosphoSitePlus	ICGC;COSMIC	18.469	Loss
Other_TTK_TTK_ST	P33981	TTK	P33981	TTK	T676	T675A	675	Missense	proximal	-1	no	22.808	19.913	EPSD;PhosphoSitePlus	ICGC;COSMIC	18.469	Down-regulation
Other_TTK_TTK_ST	P33981	TTK	P33981	TTK	S677	T675A	675	Missense	proximal	-2	no	22.366	22.191	EPSD;PhosphoSitePlus	ICGC;COSMIC	18.469	Down-regulation
Other_TTK_TTK_ST	P33981	TTK	P33981	TTK	T831	G838S	838	Missense	distal	7	no	20.126	20.630	EPSD	ICGC;COSMIC	18.469	Up-regulation
Other_TTK_TTK_ST	P33981	TTK	P33981	TTK	S845	G838S	838	Missense	distal	-7	no	20.477	21.274	EPSD;PhosphoSitePlus	ICGC;COSMIC	18.469	Up-regulation
Other_TTK_TTK_ST	P07900	HSP90AA1	P33981	TTK	S68	D66Y	66	Missense	proximal	-2	no	18.827	18.354	EPSD	ICGC;COSMIC	18.469	Loss
Other_TTK_TTK_ST	P07900	HSP90AA1	P33981	TTK	S68	T65K	65	Missense	distal	-3	no	18.827	18.388	EPSD	ICGC	18.469	Loss
Other_TTK_TTK_ST	P07900	HSP90AA1	P33981	TTK	S68	E75V	75	Missense	distal	7	no	18.827	17.875	EPSD	ICGC;COSMIC	18.469	Loss
Other_TTK_TTK_ST	P07900	HSP90AA1	P33981	TTK	T88	V92M	92	Missense	distal	4	no	18.644	19.218	EPSD	ICGC	18.469	Up-regulation
Other_TTK_TTK_ST	P07900	HSP90AA1	P33981	TTK	T88	G95R	95	Missense	distal	7	no	18.644	20.324	EPSD	ICGC;COSMIC	18.469	Up-regulation
Other_TTK_TTK_ST	P07900	HSP90AA1	P33981	TTK	T88	N83K	83	Missense	distal	-5	no	18.644	17.652	EPSD	ICGC	18.469	Loss
Other_TTK_TTK_ST	P07900	HSP90AA1	P33981	TTK	T88	D86Y	86	Missense	proximal	-2	no	18.644	18.171	EPSD	ICGC;COSMIC	18.469	Loss
Other_TTK_TTK_ST	P07900	HSP90AA1	P33981	TTK	T88	L89P	89	Missense	proximal	1	no	18.644	18.621	EPSD	ICGC;COSMIC	18.469	Down-regulation
Other_TTK_TTK_ST	P07900	HSP90AA1	P33981	TTK	T88	T94N	94	Missense	distal	6	no	18.644	17.979	EPSD	ICGC;COSMIC	18.469	Loss
Other_TTK_TTK_ST	P07900	HSP90AA1	P33981	TTK	T115	A117S	117	Missense	proximal	2	no	23.955	22.411	PhosphoSitePlus	ICGC;COSMIC	18.469	Down-regulation
Other_TTK_TTK_ST	P07900	HSP90AA1	P33981	TTK	T293	R299S	299	Missense	distal	6	no	18.642	18.716	EPSD	ICGC;COSMIC	18.469	Up-regulation
Other_TTK_TTK_ST	P07900	HSP90AA1	P33981	TTK	T293	N291S	291	Missense	proximal	-2	no	18.642	18.225	EPSD	ICGC;COSMIC	18.469	Loss
Other_TTK_TTK_ST	P07900	HSP90AA1	P33981	TTK	T305	R299S	299	Missense	distal	-6	no	20.048	20.096	EPSD	ICGC;COSMIC	18.469	Up-regulation
Other_TTK_TTK_ST	P07900	HSP90AA1	P33981	TTK	T305	G310R	310	Missense	distal	5	no	20.048	17.042	EPSD	ICGC;COSMIC	18.469	Loss
Other_TTK_TTK_ST	P07900	HSP90AA1	P33981	TTK	T305	E307K	307	Missense	proximal	2	no	20.048	19.784	EPSD	ICGC;COSMIC	18.469	Down-regulation
Other_TTK_TTK_ST	P07900	HSP90AA1	P33981	TTK	T305	I304V	304	Missense	proximal	-1	no	20.048	18.685	EPSD	ICGC;COSMIC	18.469	Down-regulation
Other_TTK_TTK_ST	P07900	HSP90AA1	P33981	TTK	T305	F312L	312	Missense	distal	7	no	20.048	21.430	EPSD	ICGC;COSMIC	18.469	Up-regulation
Other_TTK_TTK_ST	P07900	HSP90AA1	P33981	TTK	S476	A469T	469	Missense	distal	-7	no	19.384	19.375	EPSD	ICGC	18.469	Down-regulation
Other_TTK_TTK_ST	P07900	HSP90AA1	P33981	TTK	S476	Y480H	480	Missense	distal	4	no	19.384	20.353	EPSD	ICGC;COSMIC	18.469	Up-regulation
Other_TTK_TTK_ST	P07900	HSP90AA1	P33981	TTK	S505	D500N	500	Missense	distal	-5	no	17.636	19.202	EPSD	ICGC;COSMIC	18.469	Gain
Other_TTK_TTK_ST	P07900	HSP90AA1	P33981	TTK	T540	V542M	542	Missense	proximal	2	no	21.749	23.039	EPSD	ICGC;COSMIC	18.469	Up-regulation
Other_TTK_TTK_ST	P07900	HSP90AA1	P33981	TTK	T540	L541S	541	Missense	proximal	1	no	21.749	21.738	EPSD	ICGC;COSMIC	18.469	Down-regulation
Other_TTK_TTK_ST	P07900	HSP90AA1	P33981	TTK	T540	L533V	533	Missense	distal	-7	no	21.749	24.203	EPSD	ICGC;COSMIC	18.469	Up-regulation
Other_TTK_TTK_ST	P07900	HSP90AA1	P33981	TTK	S595	I599V	599	Missense	distal	4	no	19.471	19.402	EPSD	ICGC;COSMIC	18.469	Down-regulation
Other_TTK_TTK_ST	P07900	HSP90AA1	P33981	TTK	S595	S595F	595	Missense	central	0	yes	19.471	0.000	EPSD	ICGC;COSMIC	18.469	Loss
Other_TTK_TTK_ST	P07900	HSP90AA1	P33981	TTK	S595	V600I	600	Missense	distal	5	no	19.471	18.517	EPSD	ICGC;COSMIC	18.469	Down-regulation
Other_TTK_TTK_ST	P07900	HSP90AA1	P33981	TTK	T624	T624K	624	Missense	central	0	yes	21.880	0.000	EPSD	ICGC	18.469	Loss
Other_TTK_TTK_ST	P07900	HSP90AA1	P33981	TTK	T624	A630E	630	Missense	distal	6	no	21.880	21.306	EPSD	ICGC	18.469	Down-regulation
Other_TTK_TTK_ST	P07900	HSP90AA1	P33981	TTK	T624	M628V	628	Missense	distal	4	no	21.880	21.306	EPSD	ICGC;COSMIC	18.469	Down-regulation
Other_TTK_TTK_ST	P07900	HSP90AA1	P33981	TTK	S709	D702G	702	Missense	distal	-7	no	18.347	18.781	EPSD	ICGC;COSMIC	18.469	Gain
Other_TTK_TTK_ST	Q53HL2	CDCA8	P33981	TTK	T88	T94N	94	Missense	distal	6	no	25.265	24.600	EPSD;PhosphoSitePlus	ICGC	18.469	Down-regulation
Other_TTK_TTK_ST	Q53HL2	CDCA8	P33981	TTK	T88	A86V	86	Missense	proximal	-2	no	25.265	24.825	EPSD;PhosphoSitePlus	ICGC;COSMIC	18.469	Down-regulation
Other_TTK_TTK_ST	Q53HL2	CDCA8	P33981	TTK	T94	T94N	94	Missense	central	0	yes	24.948	0.000	PhosphoSitePlus;EPSD	ICGC	18.469	Loss
Other_TTK_TTK_ST	Q53HL2	CDCA8	P33981	TTK	T100	T94N	94	Missense	distal	-6	no	20.199	20.113	EPSD	ICGC	18.469	Down-regulation
Other_TTK_TTK_ST	Q53HL2	CDCA8	P33981	TTK	T152	G159R	159	Missense	distal	7	no	17.175	18.855	EPSD	ICGC;COSMIC	18.469	Gain
Other_TTK_TTK_ST	Q53HL2	CDCA8	P33981	TTK	T169	R166H	166	Missense	distal	-3	no	26.238	25.019	EPSD;PhosphoSitePlus	ICGC;COSMIC	18.469	Down-regulation
Other_TTK_TTK_ST	Q53HL2	CDCA8	P33981	TTK	T169	R176L	176	Missense	distal	7	no	26.238	25.406	EPSD;PhosphoSitePlus	ICGC	18.469	Down-regulation
Other_TTK_TTK_ST	Q53HL2	CDCA8	P33981	TTK	T199	T204A	204	Missense	distal	5	no	18.699	17.624	EPSD	ICGC;GDSC;CCLE	18.469	Loss
Other_TTK_TTK_ST	Q53HL2	CDCA8	P33981	TTK	S224	P220H	220	Missense	distal	-4	no	18.527	18.581	EPSD	ICGC;COSMIC	18.469	Up-regulation
Other_TTK_TTK_ST	Q53HL2	CDCA8	P33981	TTK	S224	T230I	230	Missense	distal	6	no	18.527	15.968	EPSD	ICGC	18.469	Loss
Other_TTK_TTK_ST	Q53HL2	CDCA8	P33981	TTK	T230	E237K	237	Missense	distal	7	no	20.157	19.485	EPSD;PhosphoSitePlus	ICGC;COSMIC	18.469	Down-regulation
Other_TTK_TTK_ST	Q53HL2	CDCA8	P33981	TTK	T230	T230I	230	Missense	central	0	yes	20.157	0.000	EPSD;PhosphoSitePlus	ICGC	18.469	Loss
Other_TTK_TTK_ST	Q53HL2	CDCA8	P33981	TTK	S238	E237K	237	Missense	proximal	-1	no	24.657	25.667	EPSD;PhosphoSitePlus	ICGC;COSMIC	18.469	Up-regulation
Other_TTK_TTK_ST	Q53HL2	CDCA8	P33981	TTK	S238	S244I	244	Missense	distal	6	no	24.657	23.593	EPSD;PhosphoSitePlus	ICGC	18.469	Down-regulation
Other_TTK_TTK_ST	P54132	BLM	P33981	TTK	S43	T50S	50	Missense	distal	7	no	19.360	20.073	EPSD	ICGC;COSMIC	18.469	Up-regulation
Other_TTK_TTK_ST	P54132	BLM	P33981	TTK	S144	S147Y	147	Missense	distal	3	no	23.538	25.648	EPSD;PhosphoSitePlus	ICGC	18.469	Up-regulation
Other_TTK_TTK_ST	P54132	BLM	P33981	TTK	T150	D153H	153	Missense	distal	3	no	17.737	20.813	EPSD	ICGC;COSMIC	18.469	Gain
Other_TTK_TTK_ST	P54132	BLM	P33981	TTK	S328	V334F	334	Missense	distal	6	no	20.257	19.675	EPSD	ICGC	18.469	Down-regulation
Other_TTK_TTK_ST	P54132	BLM	P33981	TTK	S328	V334I	334	Missense	distal	6	no	20.257	19.722	EPSD	ICGC;COSMIC	18.469	Down-regulation
Other_TTK_TTK_ST	P54132	BLM	P33981	TTK	S367	Q365L	365	Missense	proximal	-2	no	20.330	19.818	EPSD	ICGC;COSMIC	18.469	Down-regulation
Other_TTK_TTK_ST	P54132	BLM	P33981	TTK	S503	W505L	505	Missense	proximal	2	no	19.605	20.671	EPSD	ICGC	18.469	Up-regulation
Other_TTK_TTK_ST	P54132	BLM	P33981	TTK	S517	Y519C	519	Missense	proximal	2	no	19.139	17.962	EPSD	ICGC;COSMIC	18.469	Loss
Other_TTK_TTK_ST	P54132	BLM	P33981	TTK	T581	S579Y	579	Missense	proximal	-2	no	19.411	19.114	EPSD	ICGC;COSMIC	18.469	Down-regulation
Other_TTK_TTK_ST	P54132	BLM	P33981	TTK	T581	S580F	580	Missense	proximal	-1	no	19.411	16.439	EPSD	ICGC;COSMIC	18.469	Loss
Other_TTK_TTK_ST	P54132	BLM	P33981	TTK	T742	G739C	739	Missense	distal	-3	no	18.976	18.923	EPSD	ICGC	18.469	Down-regulation
Other_TTK_TTK_ST	P54132	BLM	P33981	TTK	T742	K741N	741	Missense	proximal	-1	no	18.976	20.098	EPSD	ICGC	18.469	Up-regulation
Other_TTK_TTK_ST	P54132	BLM	P33981	TTK	T903	Q909H	909	Missense	distal	6	no	19.109	16.327	EPSD	ICGC	18.469	Loss
Other_TTK_TTK_ST	P54132	BLM	P33981	TTK	T903	Q909R	909	Missense	distal	6	no	19.109	17.811	EPSD	ICGC;COSMIC	18.469	Loss
Other_TTK_TTK_ST	P54132	BLM	P33981	TTK	T903	T907M	907	Missense	distal	4	no	19.109	20.088	EPSD	ICGC;COSMIC	18.469	Up-regulation
Other_TTK_TTK_ST	P54132	BLM	P33981	TTK	S1195	S1196R	1196	Missense	proximal	1	no	20.068	20.072	EPSD	ICGC;COSMIC	18.469	Up-regulation
Other_TTK_TTK_ST	P54132	BLM	P33981	TTK	S1196	S1196R	1196	Missense	central	0	yes	18.832	0.000	EPSD	ICGC;COSMIC	18.469	Loss
Other_TTK_TTK_ST	P54132	BLM	P33981	TTK	S1290	P1297Q	1297	Missense	distal	7	no	21.545	22.013	EPSD;PhosphoSitePlus	ICGC;COSMIC	18.469	Up-regulation
Other_TTK_TTK_ST	P54132	BLM	P33981	TTK	S1296	P1297Q	1297	Missense	proximal	1	no	20.115	20.114	PhosphoSitePlus;EPSD	ICGC;COSMIC	18.469	Down-regulation
Other_TTK_TTK_ST	P54132	BLM	P33981	TTK	S1374	S1375G	1375	Missense	proximal	1	no	19.292	19.275	EPSD	ICGC	18.469	Down-regulation
Other_TTK_TTK_ST	P54132	BLM	P33981	TTK	S1374	S1368P	1368	Missense	distal	-6	no	19.292	19.206	EPSD	ICGC;COSMIC	18.469	Down-regulation
Other_TTK_TTK_ST	P54132	BLM	P33981	TTK	S1374	G1378V	1378	Missense	distal	4	no	19.292	20.875	EPSD	ICGC	18.469	Up-regulation
Other_TTK_TTK_ST	P54132	BLM	P33981	TTK	S1390	G1397E	1397	Missense	distal	7	no	18.823	20.295	EPSD	ICGC	18.469	Up-regulation
Other_TTK_TTK_ST	P54132	BLM	P33981	TTK	S1394	G1397E	1397	Missense	distal	3	no	15.179	21.303	EPSD	ICGC	18.469	Gain
Other_TTK_TTK_ST	P00519	ABL1	P33981	TTK	T79	F72V	72	Missense	distal	-7	no	16.087	19.767	EPSD	ICGC;COSMIC	18.469	Gain
Other_TTK_TTK_ST	P00519	ABL1	P33981	TTK	T83	G85C	85	Missense	proximal	2	no	19.018	18.585	EPSD	ICGC;COSMIC	18.469	Down-regulation
Other_TTK_TTK_ST	P00519	ABL1	P33981	TTK	T83	K87N	87	Missense	distal	4	no	19.018	18.580	EPSD	ICGC;COSMIC	18.469	Down-regulation
Other_TTK_TTK_ST	P00519	ABL1	P33981	TTK	T117	V111L	111	Missense	distal	-6	no	20.666	20.510	EPSD	ICGC;COSMIC	18.469	Down-regulation
Other_TTK_TTK_ST	P00519	ABL1	P33981	TTK	T117	V119F	119	Missense	proximal	2	no	20.666	20.905	EPSD	ICGC	18.469	Up-regulation
Other_TTK_TTK_ST	P00519	ABL1	P33981	TTK	S190	T194A	194	Missense	distal	4	no	18.257	18.788	EPSD	ICGC;COSMIC	18.469	Gain
Other_TTK_TTK_ST	P00519	ABL1	P33981	TTK	S190	E189G	189	Missense	proximal	-1	no	18.257	18.817	EPSD	ICGC;COSMIC	18.469	Gain
Other_TTK_TTK_ST	P00519	ABL1	P33981	TTK	S446	Y440H	440	Missense	distal	-6	no	19.172	19.281	EPSD	ICGC;COSMIC	18.469	Up-regulation
Other_TTK_TTK_ST	P00519	ABL1	P33981	TTK	S446	E453Q	453	Missense	distal	7	no	19.172	18.456	EPSD	ICGC;COSMIC	18.469	Loss
Other_TTK_TTK_ST	P00519	ABL1	P33981	TTK	S446	Y449C	449	Missense	distal	3	no	19.172	14.691	EPSD	ICGC;COSMIC	18.469	Loss
Other_TTK_TTK_ST	P00519	ABL1	P33981	TTK	T532	P529S	529	Missense	distal	-3	no	18.272	20.084	EPSD	ICGC;COSMIC	18.469	Gain
Other_TTK_TTK_ST	P00519	ABL1	P33981	TTK	T597	L599F	599	Missense	proximal	2	no	20.253	19.584	EPSD	ICGC	18.469	Down-regulation
Other_TTK_TTK_ST	P00519	ABL1	P33981	TTK	T597	S601G	601	Missense	distal	4	no	20.253	18.620	EPSD	ICGC;COSMIC	18.469	Down-regulation
Other_TTK_TTK_ST	P00519	ABL1	P33981	TTK	T597	S601R	601	Missense	distal	4	no	20.253	19.311	EPSD	ICGC;COSMIC	18.469	Down-regulation
Other_TTK_TTK_ST	P00519	ABL1	P33981	TTK	S690	H685R	685	Missense	distal	-5	no	18.901	18.608	EPSD	ICGC;COSMIC	18.469	Down-regulation
Other_TTK_TTK_ST	P00519	ABL1	P33981	TTK	S690	K688N	688	Missense	proximal	-2	no	18.901	19.278	EPSD	ICGC;COSMIC	18.469	Up-regulation
Other_TTK_TTK_ST	P00519	ABL1	P33981	TTK	S690	T692M	692	Missense	proximal	2	no	18.901	19.664	EPSD	ICGC	18.469	Up-regulation
Other_TTK_TTK_ST	P00519	ABL1	P33981	TTK	S708	R712H	712	Missense	distal	4	no	18.040	18.808	EPSD	ICGC;COSMIC	18.469	Gain
Other_TTK_TTK_ST	P00519	ABL1	P33981	TTK	S708	G701S	701	Missense	distal	-7	no	18.040	18.836	EPSD	ICGC;CCLE	18.469	Gain
Other_TTK_TTK_ST	P00519	ABL1	P33981	TTK	S709	R712H	712	Missense	distal	3	no	18.557	20.108	EPSD	ICGC;COSMIC	18.469	Up-regulation
Other_TTK_TTK_ST	P00519	ABL1	P33981	TTK	S709	G706S	706	Missense	distal	-3	no	18.557	19.630	EPSD	ICGC;COSMIC	18.469	Up-regulation
Other_TTK_TTK_ST	P00519	ABL1	P33981	TTK	S709	R715H	715	Missense	distal	6	no	18.557	17.074	EPSD	ICGC;COSMIC	18.469	Loss
Other_TTK_TTK_ST	P00519	ABL1	P33981	TTK	S709	K711N	711	Missense	proximal	2	no	18.557	18.656	EPSD	ICGC;COSMIC	18.469	Up-regulation
Other_TTK_TTK_ST	P00519	ABL1	P33981	TTK	S709	S709F	709	Missense	central	0	yes	18.557	0.000	EPSD	ICGC;COSMIC	18.469	Loss
Other_TTK_TTK_ST	P00519	ABL1	P33981	TTK	S709	R715C	715	Missense	distal	6	no	18.557	17.420	EPSD	ICGC;CCLE	18.469	Loss
Other_TTK_TTK_ST	P00519	ABL1	P33981	TTK	T735	D728Y	728	Missense	distal	-7	no	23.873	24.140	PhosphoSitePlus	ICGC	18.469	Up-regulation
Other_TTK_TTK_ST	P00519	ABL1	P33981	TTK	T735	S742F	742	Missense	distal	7	no	23.873	22.835	PhosphoSitePlus	ICGC;COSMIC	18.469	Down-regulation
Other_TTK_TTK_ST	P00519	ABL1	P33981	TTK	S919	A922V	922	Missense	distal	3	no	18.968	19.913	EPSD	ICGC;COSMIC;CCLE	18.469	Up-regulation
Other_TTK_TTK_ST	P00519	ABL1	P33981	TTK	S919	E921D	921	Missense	proximal	2	no	18.968	18.790	EPSD	ICGC;COSMIC	18.469	Down-regulation
Other_TTK_TTK_ST	P00519	ABL1	P33981	TTK	S919	P918L	918	Missense	proximal	-1	no	18.968	19.872	EPSD	ICGC;COSMIC	18.469	Up-regulation
Other_TTK_TTK_ST	P00519	ABL1	P33981	TTK	S968	P961S	961	Missense	distal	-7	no	19.276	21.063	EPSD	ICGC;COSMIC	18.469	Up-regulation
Other_TTK_TTK_ST	P00519	ABL1	P33981	TTK	S968	A969T	969	Missense	proximal	1	no	19.276	19.307	EPSD	ICGC;COSMIC;CCLE	18.469	Up-regulation
Other_TTK_TTK_ST	P00519	ABL1	P33981	TTK	S968	P971L	971	Missense	distal	3	no	19.276	24.487	EPSD	ICGC;COSMIC	18.469	Up-regulation
Other_TTK_TTK_ST	P00519	ABL1	P33981	TTK	S968	P971S	971	Missense	distal	3	no	19.276	23.480	EPSD	ICGC;COSMIC	18.469	Up-regulation
Other_TTK_TTK_ST	P00519	ABL1	P33981	TTK	S968	P961L	961	Missense	distal	-7	no	19.276	19.660	EPSD	ICGC;COSMIC	18.469	Up-regulation
Other_TTK_TTK_ST	P00519	ABL1	P33981	TTK	T1103	S1106I	1106	Missense	distal	3	no	19.600	21.451	EPSD	ICGC	18.469	Up-regulation
Other_TTK_TTK_ST	P00519	ABL1	P33981	TTK	T1103	P1108L	1108	Missense	distal	5	no	19.600	18.824	EPSD	ICGC;COSMIC	18.469	Down-regulation
Other_TTK_TTK_ST	P00519	ABL1	P33981	TTK	T1103	P1101Q	1101	Missense	proximal	-2	no	19.600	20.406	EPSD	ICGC;COSMIC	18.469	Up-regulation
Other_TTK_TTK_ST	P00519	ABL1	P33981	TTK	T1103	C1100Y	1100	Missense	distal	-3	no	19.600	16.007	EPSD	ICGC	18.469	Loss
Other_TTK_TTK_ST	P00519	ABL1	P33981	TTK	S1106	P1108L	1108	Missense	proximal	2	no	18.277	18.875	EPSD	ICGC;COSMIC	18.469	Gain
Other_TTK_TTK_ST	P00519	ABL1	P33981	TTK	S1106	P1101Q	1101	Missense	distal	-5	no	18.277	19.400	EPSD	ICGC;COSMIC	18.469	Gain
Other_TTK_TTK_ST	P38646	HSPA9	P33981	TTK	T62	S65Y	65	Missense	distal	3	no	19.274	21.383	PhosphoSitePlus;EPSD	ICGC;COSMIC	18.469	Up-regulation
Other_TTK_TTK_ST	P38646	HSPA9	P33981	TTK	T62	G61C	61	Missense	proximal	-1	no	19.274	17.424	PhosphoSitePlus;EPSD	ICGC;COSMIC	18.469	Loss
Other_TTK_TTK_ST	P38646	HSPA9	P33981	TTK	S65	S65Y	65	Missense	central	0	yes	22.920	0.000	EPSD;PhosphoSitePlus	ICGC;COSMIC	18.469	Loss
Other_TTK_TTK_ST	P38646	HSPA9	P33981	TTK	S65	G61C	61	Missense	distal	-4	no	22.920	22.926	EPSD;PhosphoSitePlus	ICGC;COSMIC	18.469	Up-regulation
Other_TTK_TTK_ST	P38646	HSPA9	P33981	TTK	T177	G183W	183	Missense	distal	6	no	18.852	17.443	EPSD	ICGC;COSMIC	18.469	Loss
Other_TTK_TTK_ST	P38646	HSPA9	P33981	TTK	T192	P194Q	194	Missense	proximal	2	no	17.475	19.044	EPSD	ICGC;COSMIC	18.469	Gain
Other_TTK_TTK_ST	P38646	HSPA9	P33981	TTK	T249	I252V	252	Missense	distal	3	no	19.459	17.750	EPSD	ICGC;COSMIC	18.469	Loss
Other_TTK_TTK_ST	P38646	HSPA9	P33981	TTK	T294	K300T	300	Missense	distal	6	no	19.101	19.722	EPSD	ICGC;COSMIC	18.469	Up-regulation
Other_TTK_TTK_ST	P38646	HSPA9	P33981	TTK	T299	K300T	300	Missense	proximal	1	no	19.168	19.190	EPSD	ICGC;COSMIC	18.469	Up-regulation
Other_TTK_TTK_ST	P38646	HSPA9	P33981	TTK	T390	M389T	389	Missense	proximal	-1	no	16.722	20.351	EPSD	ICGC;COSMIC	18.469	Gain
Other_TTK_TTK_ST	P38646	HSPA9	P33981	TTK	S638	A637T	637	Missense	proximal	-1	no	17.400	20.295	EPSD	ICGC	18.469	Gain
Other_TTK_TTK_ST	P38646	HSPA9	P33981	TTK	S644	A643E	643	Missense	proximal	-1	no	18.429	18.628	EPSD	ICGC	18.469	Gain
Other_TTK_TTK_ST	O60566	BUB1B	P33981	TTK	T474	E469K	469	Missense	distal	-5	no	18.988	17.799	EPSD	ICGC;COSMIC	18.469	Loss
Other_TTK_TTK_ST	Q9Y6D9	MAD1L1	P33981	TTK	T8	G5R	5	Missense	distal	-3	no	17.441	18.674	EPSD;PhosphoSitePlus	ICGC	18.469	Gain
Other_TTK_TTK_ST	Q9Y6D9	MAD1L1	P33981	TTK	S62	E56K	56	Missense	distal	-6	no	22.273	22.287	EPSD;PhosphoSitePlus	ICGC;COSMIC	18.469	Up-regulation
Other_TTK_TTK_ST	Q9Y6D9	MAD1L1	P33981	TTK	T91	R87L	87	Missense	distal	-4	no	19.834	19.856	EPSD	ICGC;COSMIC	18.469	Up-regulation
Other_TTK_TTK_ST	Q9Y6D9	MAD1L1	P33981	TTK	T91	R87Q	87	Missense	distal	-4	no	19.834	19.928	EPSD	ICGC;COSMIC	18.469	Up-regulation
Other_TTK_TTK_ST	Q9Y6D9	MAD1L1	P33981	TTK	S185	Q188L	188	Missense	distal	3	no	19.003	21.316	EPSD	ICGC;COSMIC	18.469	Up-regulation
Other_TTK_TTK_ST	Q9Y6D9	MAD1L1	P33981	TTK	T423	E426Q	426	Missense	distal	3	no	20.190	18.471	EPSD	ICGC;COSMIC	18.469	Down-regulation
Other_TTK_TTK_ST	Q9Y6D9	MAD1L1	P33981	TTK	S428	E426Q	426	Missense	proximal	-2	no	19.866	20.288	EPSD	ICGC;COSMIC	18.469	Up-regulation
Other_TTK_TTK_ST	Q9Y6D9	MAD1L1	P33981	TTK	S551	R558Q	558	Missense	distal	7	no	20.587	19.663	EPSD	ICGC;COSMIC	18.469	Down-regulation
Other_TTK_TTK_ST	Q9Y6D9	MAD1L1	P33981	TTK	T624	Q623R	623	Missense	proximal	-1	no	23.499	19.371	EPSD;PhosphoSitePlus	ICGC;COSMIC	18.469	Down-regulation
Other_TTK_TTK_ST	Q96PE2	ARHGEF17	P33981	TTK	S320	G325E	325	Missense	distal	5	no	20.648	17.178	EPSD	ICGC;COSMIC	18.469	Loss
Other_TTK_TTK_ST	Q96PE2	ARHGEF17	P33981	TTK	T473	R479C	479	Missense	distal	6	no	18.899	17.762	EPSD	ICGC;COSMIC	18.469	Loss
Other_TTK_TTK_ST	Q96PE2	ARHGEF17	P33981	TTK	T473	R479H	479	Missense	distal	6	no	18.899	17.415	EPSD	ICGC;COSMIC	18.469	Loss
Other_TTK_TTK_ST	Q96PE2	ARHGEF17	P33981	TTK	T473	A468S	468	Missense	distal	-5	no	18.899	18.014	EPSD	ICGC;COSMIC	18.469	Loss
Other_TTK_TTK_ST	Q96PE2	ARHGEF17	P33981	TTK	T473	I467T	467	Missense	distal	-6	no	18.899	18.737	EPSD	ICGC	18.469	Down-regulation
Other_TTK_TTK_ST	Q96PE2	ARHGEF17	P33981	TTK	S507	D503Y	503	Missense	distal	-4	no	18.927	18.920	EPSD	ICGC;COSMIC	18.469	Down-regulation
Other_TTK_TTK_ST	Q96PE2	ARHGEF17	P33981	TTK	S507	A510S	510	Missense	distal	3	no	18.927	19.729	EPSD	ICGC;COSMIC	18.469	Up-regulation
Other_TTK_TTK_ST	Q96PE2	ARHGEF17	P33981	TTK	T702	S696L	696	Missense	distal	-6	no	20.131	20.059	EPSD	ICGC	18.469	Down-regulation
Other_TTK_TTK_ST	Q96PE2	ARHGEF17	P33981	TTK	T751	G752W	752	Missense	proximal	1	no	22.091	22.137	EPSD;PhosphoSitePlus	ICGC;COSMIC	18.469	Up-regulation
Other_TTK_TTK_ST	Q96PE2	ARHGEF17	P33981	TTK	T780	W786C	786	Missense	distal	6	no	19.375	19.141	EPSD	ICGC	18.469	Down-regulation
Other_TTK_TTK_ST	Q96PE2	ARHGEF17	P33981	TTK	T780	L779F	779	Missense	proximal	-1	no	19.375	18.126	EPSD	ICGC	18.469	Loss
Other_TTK_TTK_ST	Q96PE2	ARHGEF17	P33981	TTK	S790	W786C	786	Missense	distal	-4	no	20.573	20.634	EPSD	ICGC	18.469	Up-regulation
Other_TTK_TTK_ST	Q96PE2	ARHGEF17	P33981	TTK	S827	D830E	830	Missense	distal	3	no	19.563	21.124	EPSD	ICGC	18.469	Up-regulation
Other_TTK_TTK_ST	Q96PE2	ARHGEF17	P33981	TTK	S827	R833C	833	Missense	distal	6	no	19.563	18.426	EPSD	ICGC;COSMIC	18.469	Loss
Other_TTK_TTK_ST	Q96PE2	ARHGEF17	P33981	TTK	S827	D830V	830	Missense	distal	3	no	19.563	20.855	EPSD	ICGC;COSMIC	18.469	Up-regulation
Other_TTK_TTK_ST	Q96PE2	ARHGEF17	P33981	TTK	S827	G820D	820	Missense	distal	-7	no	19.563	19.130	EPSD	ICGC;COSMIC	18.469	Down-regulation
Other_TTK_TTK_ST	Q96PE2	ARHGEF17	P33981	TTK	T944	G939V	939	Missense	distal	-5	no	23.911	26.361	EPSD;PhosphoSitePlus	ICGC	18.469	Up-regulation
Other_TTK_TTK_ST	Q96PE2	ARHGEF17	P33981	TTK	T944	S948F	948	Missense	distal	4	no	23.911	22.314	EPSD;PhosphoSitePlus	ICGC;COSMIC	18.469	Down-regulation
Other_TTK_TTK_ST	Q96PE2	ARHGEF17	P33981	TTK	T1007	E1004D	1004	Missense	distal	-3	no	22.406	20.185	PhosphoSitePlus;EPSD	ICGC;COSMIC	18.469	Down-regulation
Other_TTK_TTK_ST	Q96PE2	ARHGEF17	P33981	TTK	T1007	V1006F	1006	Missense	proximal	-1	no	22.406	21.562	PhosphoSitePlus;EPSD	ICGC	18.469	Down-regulation
Other_TTK_TTK_ST	Q96PE2	ARHGEF17	P33981	TTK	T1007	D1005A	1005	Missense	proximal	-2	no	22.406	22.410	PhosphoSitePlus;EPSD	ICGC;COSMIC	18.469	Up-regulation
Other_TTK_TTK_ST	Q96PE2	ARHGEF17	P33981	TTK	T1007	D1005N	1005	Missense	proximal	-2	no	22.406	22.647	PhosphoSitePlus;EPSD	ICGC;COSMIC	18.469	Up-regulation
Other_TTK_TTK_ST	Q96PE2	ARHGEF17	P33981	TTK	T1077	E1078D	1078	Missense	proximal	1	no	19.824	19.825	EPSD	ICGC;COSMIC	18.469	Up-regulation
Other_TTK_TTK_ST	Q96PE2	ARHGEF17	P33981	TTK	S1257	R1256Q	1256	Missense	proximal	-1	no	16.057	20.185	EPSD	ICGC;COSMIC;CCLE	18.469	Gain
Other_TTK_TTK_ST	Q96PE2	ARHGEF17	P33981	TTK	S1345	S1339I	1339	Missense	distal	-6	no	19.401	19.395	EPSD	ICGC	18.469	Down-regulation
Other_TTK_TTK_ST	Q9Y6R1	SLC4A4	P33981	TTK	S77	D74Y	74	Missense	distal	-3	no	19.968	16.036	EPSD	ICGC;COSMIC	18.469	Loss
Other_TTK_TTK_ST	Q9Y6R1	SLC4A4	P33981	TTK	S223	G228W	228	Missense	distal	5	no	23.254	22.539	EPSD	ICGC;COSMIC	18.469	Down-regulation
Other_TTK_TTK_ST	Q9Y6R1	SLC4A4	P33981	TTK	S223	N220T	220	Missense	distal	-3	no	23.254	23.206	EPSD	ICGC	18.469	Down-regulation
Other_TTK_TTK_ST	Q9Y6R1	SLC4A4	P33981	TTK	S223	D226N	226	Missense	distal	3	no	23.254	23.463	EPSD	ICGC	18.469	Up-regulation
Other_TTK_TTK_ST	Q9Y6R1	SLC4A4	P33981	TTK	S233	M237I	237	Missense	distal	4	no	19.105	18.601	EPSD	ICGC;COSMIC	18.469	Down-regulation
Other_TTK_TTK_ST	Q9Y6R1	SLC4A4	P33981	TTK	S233	G228W	228	Missense	distal	-5	no	19.105	20.062	EPSD	ICGC;COSMIC	18.469	Up-regulation
Other_TTK_TTK_ST	Q9Y6R1	SLC4A4	P33981	TTK	S233	D226N	226	Missense	distal	-7	no	19.105	19.878	EPSD	ICGC	18.469	Up-regulation
Other_TTK_TTK_ST	O96017	CHEK2	P33981	TTK	S41	T45M	45	Missense	distal	4	no	17.844	18.823	EPSD	ICGC;COSMIC	18.469	Gain
Other_TTK_TTK_ST	O96017	CHEK2	P33981	TTK	T43	G37C	37	Missense	distal	-6	no	20.136	20.333	EPSD	ICGC;COSMIC	18.469	Up-regulation
Other_TTK_TTK_ST	O96017	CHEK2	P33981	TTK	T43	M46I	46	Missense	distal	3	no	20.136	21.996	EPSD	ICGC;COSMIC	18.469	Up-regulation
Other_TTK_TTK_ST	O96017	CHEK2	P33981	TTK	T43	S49F	49	Missense	distal	6	no	20.136	19.026	EPSD	ICGC;COSMIC	18.469	Down-regulation
Other_TTK_TTK_ST	O96017	CHEK2	P33981	TTK	T43	T45M	45	Missense	proximal	2	no	20.136	20.900	EPSD	ICGC;COSMIC	18.469	Up-regulation
Other_TTK_TTK_ST	O96017	CHEK2	P33981	TTK	S50	T45M	45	Missense	distal	-5	no	17.734	18.575	EPSD	ICGC;COSMIC	18.469	Gain
Other_TTK_TTK_ST	O96017	CHEK2	P33981	TTK	S52	M46I	46	Missense	distal	-6	no	20.890	20.967	EPSD	ICGC;COSMIC	18.469	Up-regulation
Other_TTK_TTK_ST	O96017	CHEK2	P33981	TTK	S52	S49F	49	Missense	distal	-3	no	20.890	19.004	EPSD	ICGC;COSMIC	18.469	Down-regulation
Other_TTK_TTK_ST	O96017	CHEK2	P33981	TTK	S52	T45M	45	Missense	distal	-7	no	20.890	20.757	EPSD	ICGC;COSMIC	18.469	Down-regulation
Other_TTK_TTK_ST	O96017	CHEK2	P33981	TTK	S435	Q433E	433	Missense	proximal	-2	no	19.782	19.360	EPSD	ICGC;COSMIC	18.469	Down-regulation
Other_TTK_TTK_ST	O96017	CHEK2	P33981	TTK	S435	S428F	428	Missense	distal	-7	no	19.782	17.154	EPSD	ICGC;COSMIC	18.469	Loss
Other_TTK_TTK_ST	O96017	CHEK2	P33981	TTK	S435	H430Y	430	Missense	distal	-5	no	19.782	19.374	EPSD	ICGC;COSMIC	18.469	Down-regulation
Other_TTK_TTK_ST	O96017	CHEK2	P33981	TTK	S442	P449T	449	Missense	distal	7	no	21.013	20.516	EPSD	ICGC	18.469	Down-regulation
Other_TTK_TTK_ST	O96017	CHEK2	P33981	TTK	S442	F447L	447	Missense	distal	5	no	21.013	20.288	EPSD	ICGC;COSMIC	18.469	Down-regulation
Other_TTK_TTK_ST	O96017	CHEK2	P33981	TTK	T506	P509S	509	Missense	distal	3	no	15.744	19.948	EPSD	ICGC;COSMIC	18.469	Gain
Other_TTK_TTK_ST	Q6IBW4	NCAPH2	P33981	TTK	S95	R90L	90	Missense	distal	-5	no	20.265	21.310	EPSD	ICGC	18.469	Up-regulation
Other_TTK_TTK_ST	Q6IBW4	NCAPH2	P33981	TTK	S95	R90W	90	Missense	distal	-5	no	20.265	18.730	EPSD	ICGC;COSMIC;GDSC	18.469	Down-regulation
Other_TTK_TTK_ST	Q6IBW4	NCAPH2	P33981	TTK	S96	R90L	90	Missense	distal	-6	no	22.429	22.404	EPSD	ICGC	18.469	Down-regulation
Other_TTK_TTK_ST	Q6IBW4	NCAPH2	P33981	TTK	S96	R90W	90	Missense	distal	-6	no	22.429	22.537	EPSD	ICGC;COSMIC;GDSC	18.469	Up-regulation
Other_TTK_TTK_ST	Q6IBW4	NCAPH2	P33981	TTK	T138	V142F	142	Missense	distal	4	no	27.160	25.612	EPSD	ICGC;COSMIC	18.469	Down-regulation
Other_TTK_TTK_ST	Q6IBW4	NCAPH2	P33981	TTK	T481	A480T	480	Missense	proximal	-1	no	17.083	19.978	EPSD	ICGC;COSMIC	18.469	Gain
Other_TTK_TTK_ST	Q6IBW4	NCAPH2	P33981	TTK	T501	P504L	504	Missense	distal	3	no	15.931	21.142	EPSD	ICGC;COSMIC	18.469	Gain
AGC_PKC_PKCa_PRKCA_ST	P35367	HRH1	P17252	PRKCA	T140	S145L	145	Missense	distal	5	no	16.754	16.564	EPSD	ICGC;COSMIC;GDSC;CCLE	16.704	Loss
AGC_PKC_PKCa_PRKCA_ST	P35367	HRH1	P17252	PRKCA	T140	T142S	142	Missense	proximal	2	no	16.754	16.945	EPSD	ICGC	16.704	Up-regulation
AGC_PKC_PKCa_PRKCA_ST	P35367	HRH1	P17252	PRKCA	T142	S145L	145	Missense	distal	3	no	17.119	16.272	EPSD	ICGC;COSMIC;GDSC;CCLE	16.704	Loss
AGC_PKC_PKCa_PRKCA_ST	P35367	HRH1	P17252	PRKCA	S396	S396W	396	Missense	central	0	yes	21.552	0.000	EPSD;PhosphoSitePlus	ICGC;COSMIC	16.704	Loss
AGC_PKC_PKCa_PRKCA_ST	P35367	HRH1	P17252	PRKCA	S396	R393S	393	Missense	distal	-3	no	21.552	18.682	EPSD;PhosphoSitePlus	ICGC;COSMIC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	P35367	HRH1	P17252	PRKCA	S398	S396W	396	Missense	proximal	-2	no	15.911	17.215	EPSD;PhosphoSitePlus	ICGC;COSMIC	16.704	Gain
AGC_PKC_PKCa_PRKCA_ST	P35367	HRH1	P17252	PRKCA	T478	K477R	477	Missense	proximal	-1	no	17.273	17.216	PhosphoSitePlus;EPSD	ICGC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	P29474	NOS3	P17252	PRKCA	S260	G253V	253	Missense	distal	-7	no	22.224	22.219	EPSD	ICGC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	P29474	NOS3	P17252	PRKCA	S260	G263R	263	Missense	distal	3	no	22.224	22.863	EPSD	ICGC	16.704	Up-regulation
AGC_PKC_PKCa_PRKCA_ST	P29474	NOS3	P17252	PRKCA	S260	D264G	264	Missense	distal	4	no	22.224	22.218	EPSD	ICGC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	P29474	NOS3	P17252	PRKCA	S483	K481N	481	Missense	proximal	-2	no	17.071	15.502	EPSD	ICGC	16.704	Loss
AGC_PKC_PKCa_PRKCA_ST	P29474	NOS3	P17252	PRKCA	S483	A484V	484	Missense	proximal	1	no	17.071	17.224	EPSD	ICGC	16.704	Up-regulation
AGC_PKC_PKCa_PRKCA_ST	P29474	NOS3	P17252	PRKCA	T495	A500S	500	Missense	distal	5	no	21.488	21.385	PhosphoSitePlus	ICGC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	P29474	NOS3	P17252	PRKCA	T495	A502S	502	Missense	distal	7	no	21.488	21.490	PhosphoSitePlus	ICGC	16.704	Up-regulation
AGC_PKC_PKCa_PRKCA_ST	P29474	NOS3	P17252	PRKCA	T495	K493N	493	Missense	proximal	-2	no	21.488	19.919	PhosphoSitePlus	ICGC;COSMIC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	P29474	NOS3	P17252	PRKCA	S600	M593I	593	Missense	distal	-7	no	18.159	18.147	EPSD	ICGC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	P29474	NOS3	P17252	PRKCA	S600	R602L	602	Missense	proximal	2	no	18.159	13.172	EPSD	ICGC	16.704	Loss
AGC_PKC_PKCa_PRKCA_ST	P29474	NOS3	P17252	PRKCA	S600	S594Y	594	Missense	distal	-6	no	18.159	18.106	EPSD	ICGC;COSMIC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	P29474	NOS3	P17252	PRKCA	S600	R602Q	602	Missense	proximal	2	no	18.159	14.325	EPSD	ICGC;COSMIC;CCLE	16.704	Loss
AGC_PKC_PKCa_PRKCA_ST	P29474	NOS3	P17252	PRKCA	S615	S617P	617	Missense	proximal	2	no	18.397	17.815	EPSD	ICGC;COSMIC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	P29474	NOS3	P17252	PRKCA	S615	S608I	608	Missense	distal	-7	no	18.397	18.388	EPSD	ICGC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	P29474	NOS3	P17252	PRKCA	S615	P621T	621	Missense	distal	6	no	18.397	18.316	EPSD	ICGC;COSMIC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	P29474	NOS3	P17252	PRKCA	S625	R627W	627	Missense	proximal	2	no	21.855	16.415	EPSD	ICGC;COSMIC	16.704	Loss
AGC_PKC_PKCa_PRKCA_ST	P29474	NOS3	P17252	PRKCA	S625	V623L	623	Missense	proximal	-2	no	21.855	22.009	EPSD	ICGC	16.704	Up-regulation
AGC_PKC_PKCa_PRKCA_ST	P29474	NOS3	P17252	PRKCA	S625	P621T	621	Missense	distal	-4	no	21.855	21.365	EPSD	ICGC;COSMIC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	P29474	NOS3	P17252	PRKCA	S625	R628W	628	Missense	distal	3	no	21.855	18.922	EPSD	ICGC;COSMIC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	P29474	NOS3	P17252	PRKCA	S625	V623M	623	Missense	proximal	-2	no	21.855	22.716	EPSD	ICGC;COSMIC	16.704	Up-regulation
AGC_PKC_PKCa_PRKCA_ST	P29474	NOS3	P17252	PRKCA	S633	R627W	627	Missense	distal	-6	no	18.170	17.886	EPSD	ICGC;COSMIC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	P29474	NOS3	P17252	PRKCA	S633	R628W	628	Missense	distal	-5	no	18.170	17.856	EPSD	ICGC;COSMIC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	P29474	NOS3	P17252	PRKCA	S725	R732H	732	Missense	distal	7	no	17.751	17.680	EPSD	ICGC;COSMIC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	P29474	NOS3	P17252	PRKCA	S725	R732C	732	Missense	distal	7	no	17.751	17.528	EPSD	ICGC;COSMIC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	P29474	NOS3	P17252	PRKCA	S725	A719S	719	Missense	distal	-6	no	17.751	17.788	EPSD	ICGC	16.704	Up-regulation
AGC_PKC_PKCa_PRKCA_ST	P29474	NOS3	P17252	PRKCA	S725	R728Q	728	Missense	distal	3	no	17.751	15.298	EPSD	ICGC	16.704	Loss
AGC_PKC_PKCa_PRKCA_ST	P29474	NOS3	P17252	PRKCA	S725	P726L	726	Missense	proximal	1	no	17.751	18.178	EPSD	ICGC	16.704	Up-regulation
AGC_PKC_PKCa_PRKCA_ST	P29474	NOS3	P17252	PRKCA	S725	R728W	728	Missense	distal	3	no	17.751	14.817	EPSD	ICGC;COSMIC	16.704	Loss
AGC_PKC_PKCa_PRKCA_ST	P29474	NOS3	P17252	PRKCA	S738	A741S	741	Missense	distal	3	no	16.757	16.964	EPSD	ICGC	16.704	Up-regulation
AGC_PKC_PKCa_PRKCA_ST	P29474	NOS3	P17252	PRKCA	S738	R732H	732	Missense	distal	-6	no	16.757	16.689	EPSD	ICGC;COSMIC	16.704	Loss
AGC_PKC_PKCa_PRKCA_ST	P29474	NOS3	P17252	PRKCA	S738	R732C	732	Missense	distal	-6	no	16.757	16.388	EPSD	ICGC;COSMIC	16.704	Loss
AGC_PKC_PKCa_PRKCA_ST	P29474	NOS3	P17252	PRKCA	S1177	Q1176E	1176	Missense	proximal	-1	no	16.347	16.796	EPSD	ICGC;COSMIC	16.704	Gain
AGC_PKC_PKCa_PRKCA_ST	P09758	TACSTD2	P17252	PRKCA	S142	E147D	147	Missense	distal	5	no	18.250	18.158	EPSD	ICGC;COSMIC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	P09758	TACSTD2	P17252	PRKCA	S269	R272C	272	Missense	distal	3	no	17.276	14.658	EPSD	ICGC;COSMIC;GDSC;CCLE	16.704	Loss
AGC_PKC_PKCa_PRKCA_ST	Q9BR39	JPH2	P17252	PRKCA	S165	R167H	167	Missense	proximal	2	no	20.337	15.313	PhosphoSitePlus	ICGC;COSMIC	16.704	Loss
AGC_PKC_PKCa_PRKCA_ST	Q9BR39	JPH2	P17252	PRKCA	S165	R167S	167	Missense	proximal	2	no	20.337	15.717	PhosphoSitePlus	ICGC	16.704	Loss
AGC_PKC_PKCa_PRKCA_ST	Q9BR39	JPH2	P17252	PRKCA	S235	T237M	237	Missense	proximal	2	no	18.470	18.833	EPSD	ICGC;COSMIC	16.704	Up-regulation
AGC_PKC_PKCa_PRKCA_ST	Q9BR39	JPH2	P17252	PRKCA	S238	T237M	237	Missense	proximal	-1	no	17.579	18.617	EPSD	ICGC;COSMIC	16.704	Up-regulation
AGC_PKC_PKCa_PRKCA_ST	Q9BR39	JPH2	P17252	PRKCA	S238	R243H	243	Missense	distal	5	no	17.579	17.320	EPSD	ICGC;COSMIC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	Q9BR39	JPH2	P17252	PRKCA	S241	T237M	237	Missense	distal	-4	no	20.964	21.898	EPSD	ICGC;COSMIC	16.704	Up-regulation
AGC_PKC_PKCa_PRKCA_ST	Q9BR39	JPH2	P17252	PRKCA	S241	R243H	243	Missense	proximal	2	no	20.964	15.940	EPSD	ICGC;COSMIC	16.704	Loss
AGC_PKC_PKCa_PRKCA_ST	Q9BR39	JPH2	P17252	PRKCA	S244	T237M	237	Missense	distal	-7	no	17.352	17.358	EPSD	ICGC;COSMIC	16.704	Up-regulation
AGC_PKC_PKCa_PRKCA_ST	Q9BR39	JPH2	P17252	PRKCA	S244	R243H	243	Missense	proximal	-1	no	17.352	17.029	EPSD	ICGC;COSMIC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	Q9BR39	JPH2	P17252	PRKCA	S247	R243H	243	Missense	distal	-4	no	17.992	17.418	EPSD	ICGC;COSMIC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	Q9BR39	JPH2	P17252	PRKCA	S306	S309P	309	Missense	distal	3	no	18.147	18.007	EPSD	ICGC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	Q9BR39	JPH2	P17252	PRKCA	S306	V305M	305	Missense	proximal	-1	no	18.147	20.269	EPSD	ICGC;COSMIC	16.704	Up-regulation
AGC_PKC_PKCa_PRKCA_ST	Q9BR39	JPH2	P17252	PRKCA	S306	G304V	304	Missense	proximal	-2	no	18.147	18.177	EPSD	ICGC;COSMIC	16.704	Up-regulation
AGC_PKC_PKCa_PRKCA_ST	Q9BR39	JPH2	P17252	PRKCA	S306	R313C	313	Missense	distal	7	no	18.147	17.923	EPSD	ICGC;COSMIC;GDSC;CCLE	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	Q9BR39	JPH2	P17252	PRKCA	S306	S310R	310	Missense	distal	4	no	18.147	18.393	EPSD	ICGC	16.704	Up-regulation
AGC_PKC_PKCa_PRKCA_ST	Q9BR39	JPH2	P17252	PRKCA	S306	G302A	302	Missense	distal	-4	no	18.147	18.142	EPSD	ICGC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	Q9BR39	JPH2	P17252	PRKCA	S359	R352C	352	Missense	distal	-7	no	19.136	19.117	EPSD	ICGC;COSMIC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	Q9BR39	JPH2	P17252	PRKCA	S359	R363C	363	Missense	distal	4	no	19.136	17.735	EPSD	ICGC;COSMIC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	Q9BR39	JPH2	P17252	PRKCA	S359	Q356K	356	Missense	distal	-3	no	19.136	19.967	EPSD	ICGC	16.704	Up-regulation
AGC_PKC_PKCa_PRKCA_ST	Q9BR39	JPH2	P17252	PRKCA	S359	L357I	357	Missense	proximal	-2	no	19.136	18.236	EPSD	ICGC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	Q9BR39	JPH2	P17252	PRKCA	T477	R475H	475	Missense	proximal	-2	no	18.033	13.480	EPSD	ICGC;COSMIC	16.704	Loss
AGC_PKC_PKCa_PRKCA_ST	Q9BR39	JPH2	P17252	PRKCA	T477	E481K	481	Missense	distal	4	no	18.033	18.572	EPSD	ICGC	16.704	Up-regulation
AGC_PKC_PKCa_PRKCA_ST	Q9BR39	JPH2	P17252	PRKCA	T477	G483D	483	Missense	distal	6	no	18.033	18.093	EPSD	ICGC;COSMIC	16.704	Up-regulation
AGC_PKC_PKCa_PRKCA_ST	Q9BR39	JPH2	P17252	PRKCA	T477	R479Q	479	Missense	proximal	2	no	18.033	14.199	EPSD	ICGC;COSMIC	16.704	Loss
AGC_PKC_PKCa_PRKCA_ST	Q9BR39	JPH2	P17252	PRKCA	S484	E481K	481	Missense	distal	-3	no	14.773	17.685	EPSD	ICGC	16.704	Gain
AGC_PKC_PKCa_PRKCA_ST	Q9BR39	JPH2	P17252	PRKCA	S534	R533H	533	Missense	proximal	-1	no	19.046	18.723	EPSD	ICGC;COSMIC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	Q9BR39	JPH2	P17252	PRKCA	S534	A530T	530	Missense	distal	-4	no	19.046	18.298	EPSD	ICGC;COSMIC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	Q9BR39	JPH2	P17252	PRKCA	T540	R533H	533	Missense	distal	-7	no	18.930	18.923	EPSD	ICGC;COSMIC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	Q9BR39	JPH2	P17252	PRKCA	S597	P599R	599	Missense	proximal	2	no	12.337	17.539	EPSD	ICGC;COSMIC	16.704	Gain
AGC_PKC_PKCa_PRKCA_ST	P29966	MARCKS	P17252	PRKCA	T8	A9S	9	Missense	proximal	1	no	17.088	16.290	EPSD	ICGC	16.704	Loss
AGC_PKC_PKCa_PRKCA_ST	P29966	MARCKS	P17252	PRKCA	T150	P144S	144	Missense	distal	-6	no	18.612	18.644	EPSD	ICGC;COSMIC	16.704	Up-regulation
AGC_PKC_PKCa_PRKCA_ST	P29966	MARCKS	P17252	PRKCA	S163	F169C	169	Missense	distal	6	no	23.529	23.402	EPSD;PhosphoSitePlus	ICGC;COSMIC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	P29966	MARCKS	P17252	PRKCA	S170	F169C	169	Missense	proximal	-1	no	21.726	20.161	EPSD;PhosphoSitePlus	ICGC;COSMIC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	P29966	MARCKS	P17252	PRKCA	S170	K175Q	175	Missense	distal	5	no	21.726	21.573	EPSD;PhosphoSitePlus	ICGC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	Q92879	CELF1	P17252	PRKCA	S28	P24S	24	Missense	distal	-4	no	18.731	18.902	EPSD;PhosphoSitePlus	ICGC;COSMIC	16.704	Up-regulation
AGC_PKC_PKCa_PRKCA_ST	Q92879	CELF1	P17252	PRKCA	S28	L35P	35	Missense	distal	7	no	18.731	18.765	EPSD;PhosphoSitePlus	ICGC;COSMIC	16.704	Up-regulation
AGC_PKC_PKCa_PRKCA_ST	Q92879	CELF1	P17252	PRKCA	S28	E29Q	29	Missense	proximal	1	no	18.731	20.181	EPSD;PhosphoSitePlus	ICGC;COSMIC	16.704	Up-regulation
AGC_PKC_PKCa_PRKCA_ST	Q92879	CELF1	P17252	PRKCA	S28	R25M	25	Missense	distal	-3	no	18.731	15.759	EPSD;PhosphoSitePlus	ICGC;COSMIC	16.704	Loss
AGC_PKC_PKCa_PRKCA_ST	Q92879	CELF1	P17252	PRKCA	S129	Q133K	133	Missense	distal	4	no	16.705	17.093	EPSD	ICGC	16.704	Up-regulation
AGC_PKC_PKCa_PRKCA_ST	Q92879	CELF1	P17252	PRKCA	S129	I124V	124	Missense	distal	-5	no	16.705	16.712	EPSD	ICGC;COSMIC	16.704	Up-regulation
AGC_PKC_PKCa_PRKCA_ST	Q92879	CELF1	P17252	PRKCA	S129	R125Q	125	Missense	distal	-4	no	16.705	16.328	EPSD	ICGC;COSMIC	16.704	Loss
AGC_PKC_PKCa_PRKCA_ST	Q92879	CELF1	P17252	PRKCA	S129	F128L	128	Missense	proximal	-1	no	16.705	16.993	EPSD	ICGC;COSMIC	16.704	Up-regulation
AGC_PKC_PKCa_PRKCA_ST	P11387	TOP1	P17252	PRKCA	S2	S2I	2	Missense	central	0	yes	17.590	0.000	EPSD	ICGC	16.704	Loss
AGC_PKC_PKCa_PRKCA_ST	P11387	TOP1	P17252	PRKCA	S2	H5Y	5	Missense	distal	3	no	17.590	16.035	EPSD	ICGC;CCLE	16.704	Loss
AGC_PKC_PKCa_PRKCA_ST	P11387	TOP1	P17252	PRKCA	S10	A14T	14	Missense	distal	4	no	16.840	16.393	EPSD	ICGC;COSMIC	16.704	Loss
AGC_PKC_PKCa_PRKCA_ST	P11387	TOP1	P17252	PRKCA	S10	H5Y	5	Missense	distal	-5	no	16.840	16.687	EPSD	ICGC;CCLE	16.704	Loss
AGC_PKC_PKCa_PRKCA_ST	P11387	TOP1	P17252	PRKCA	S10	R17Q	17	Missense	distal	7	no	16.840	16.836	EPSD	ICGC;COSMIC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	P11387	TOP1	P17252	PRKCA	S21	A14T	14	Missense	distal	-7	no	19.040	19.035	PhosphoSitePlus	ICGC;COSMIC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	P11387	TOP1	P17252	PRKCA	S21	R17Q	17	Missense	distal	-4	no	19.040	18.663	PhosphoSitePlus	ICGC;COSMIC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	P11387	TOP1	P17252	PRKCA	S21	D26Y	26	Missense	distal	5	no	19.040	19.287	PhosphoSitePlus	ICGC;COSMIC	16.704	Up-regulation
AGC_PKC_PKCa_PRKCA_ST	P11387	TOP1	P17252	PRKCA	S57	K59N	59	Missense	proximal	2	no	18.319	13.370	EPSD	ICGC;GDSC;CCLE	16.704	Loss
AGC_PKC_PKCa_PRKCA_ST	P11387	TOP1	P17252	PRKCA	S74	E75G	75	Missense	proximal	1	no	17.158	17.771	EPSD	ICGC	16.704	Up-regulation
AGC_PKC_PKCa_PRKCA_ST	P11387	TOP1	P17252	PRKCA	S423	G422V	422	Missense	proximal	-1	no	17.718	16.008	EPSD	ICGC	16.704	Loss
AGC_PKC_PKCa_PRKCA_ST	P11387	TOP1	P17252	PRKCA	T446	D440G	440	Missense	distal	-6	no	18.699	18.750	EPSD	ICGC	16.704	Up-regulation
AGC_PKC_PKCa_PRKCA_ST	P11387	TOP1	P17252	PRKCA	T446	W441L	441	Missense	distal	-5	no	18.699	18.885	EPSD	ICGC	16.704	Up-regulation
AGC_PKC_PKCa_PRKCA_ST	P11387	TOP1	P17252	PRKCA	T446	Q442H	442	Missense	distal	-4	no	18.699	18.502	EPSD	ICGC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	P11387	TOP1	P17252	PRKCA	T446	R449W	449	Missense	distal	3	no	18.699	15.766	EPSD	ICGC;COSMIC	16.704	Loss
AGC_PKC_PKCa_PRKCA_ST	P11387	TOP1	P17252	PRKCA	S534	S534F	534	Missense	central	0	yes	20.451	0.000	EPSD	ICGC;COSMIC;CCLE	16.704	Loss
AGC_PKC_PKCa_PRKCA_ST	P11387	TOP1	P17252	PRKCA	S686	A690S	690	Missense	distal	4	no	19.270	19.254	EPSD	ICGC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	Q96PH1	NOX5	P17252	PRKCA	T32	A39S	39	Missense	distal	7	no	16.877	16.879	EPSD	ICGC;COSMIC	16.704	Up-regulation
AGC_PKC_PKCa_PRKCA_ST	Q96PH1	NOX5	P17252	PRKCA	T32	L28F	28	Missense	distal	-4	no	16.877	17.250	EPSD	ICGC	16.704	Up-regulation
AGC_PKC_PKCa_PRKCA_ST	Q96PH1	NOX5	P17252	PRKCA	T32	A25S	25	Missense	distal	-7	no	16.877	16.875	EPSD	ICGC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	Q96PH1	NOX5	P17252	PRKCA	T32	T32N	32	Missense	central	0	yes	16.877	0.000	EPSD	ICGC;COSMIC	16.704	Loss
AGC_PKC_PKCa_PRKCA_ST	Q96PH1	NOX5	P17252	PRKCA	T32	V31M	31	Missense	proximal	-1	no	16.877	18.999	EPSD	ICGC;COSMIC	16.704	Up-regulation
AGC_PKC_PKCa_PRKCA_ST	Q96PH1	NOX5	P17252	PRKCA	S536	T540A	540	Missense	distal	4	no	18.737	19.184	EPSD	ICGC	16.704	Up-regulation
AGC_PKC_PKCa_PRKCA_ST	Q96PH1	NOX5	P17252	PRKCA	S536	R530H	530	Missense	distal	-6	no	18.737	18.669	EPSD	ICGC;COSMIC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	Q96PH1	NOX5	P17252	PRKCA	T540	T540A	540	Missense	central	0	yes	18.316	0.000	EPSD	ICGC	16.704	Loss
AGC_PKC_PKCa_PRKCA_ST	Q96PH1	NOX5	P17252	PRKCA	S544	T540A	540	Missense	distal	-4	no	22.733	23.481	EPSD	ICGC	16.704	Up-regulation
AGC_PKC_PKCa_PRKCA_ST	P37802	TAGLN2	P17252	PRKCA	S185	A184E	184	Missense	proximal	-1	no	16.440	17.017	PhosphoSitePlus;EPSD	ICGC	16.704	Gain
AGC_PKC_PKCa_PRKCA_ST	O76090	BEST1	P17252	PRKCA	S16	C23Y	23	Missense	distal	7	no	19.974	20.145	EPSD	ICGC;COSMIC	16.704	Up-regulation
AGC_PKC_PKCa_PRKCA_ST	O76090	BEST1	P17252	PRKCA	S16	R19C	19	Missense	distal	3	no	19.974	17.355	EPSD	ICGC;COSMIC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	O76090	BEST1	P17252	PRKCA	S16	R13C	13	Missense	distal	-3	no	19.974	17.235	EPSD	ICGC;COSMIC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	O76090	BEST1	P17252	PRKCA	S16	L21M	21	Missense	distal	5	no	19.974	20.292	EPSD	ICGC;COSMIC	16.704	Up-regulation
AGC_PKC_PKCa_PRKCA_ST	O76090	BEST1	P17252	PRKCA	S16	R13H	13	Missense	distal	-3	no	19.974	16.118	EPSD	ICGC;COSMIC;GDSC;CCLE	16.704	Loss
AGC_PKC_PKCa_PRKCA_ST	O76090	BEST1	P17252	PRKCA	S358	T363A	363	Missense	distal	5	no	22.219	22.498	PhosphoSitePlus	ICGC;COSMIC	16.704	Up-regulation
AGC_PKC_PKCa_PRKCA_ST	O76090	BEST1	P17252	PRKCA	S358	A357V	357	Missense	proximal	-1	no	22.219	21.316	PhosphoSitePlus	ICGC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	O76090	BEST1	P17252	PRKCA	S358	M360I	360	Missense	proximal	2	no	22.219	21.635	PhosphoSitePlus	ICGC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	Q15080	NCF4	P17252	PRKCA	S11	D18N	18	Missense	distal	7	no	18.416	18.389	EPSD	ICGC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	Q15080	NCF4	P17252	PRKCA	S315	R318C	318	Missense	distal	3	no	17.857	15.238	PhosphoSitePlus;EPSD	ICGC;COSMIC	16.704	Loss
AGC_PKC_PKCa_PRKCA_ST	Q15080	NCF4	P17252	PRKCA	S315	Q309H	309	Missense	distal	-6	no	17.857	17.932	PhosphoSitePlus;EPSD	ICGC	16.704	Up-regulation
AGC_PKC_PKCa_PRKCA_ST	Q15080	NCF4	P17252	PRKCA	S315	R318H	318	Missense	distal	3	no	17.857	17.144	PhosphoSitePlus;EPSD	ICGC;COSMIC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	Q15080	NCF4	P17252	PRKCA	S315	R311C	311	Missense	distal	-4	no	17.857	16.513	PhosphoSitePlus;EPSD	ICGC;COSMIC	16.704	Loss
AGC_PKC_PKCa_PRKCA_ST	Q15080	NCF4	P17252	PRKCA	S315	R308W	308	Missense	distal	-7	no	17.857	17.840	PhosphoSitePlus;EPSD	ICGC;COSMIC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	Q15080	NCF4	P17252	PRKCA	S315	R308Q	308	Missense	distal	-7	no	17.857	17.848	PhosphoSitePlus;EPSD	ICGC;COSMIC;GDSC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	P16144	ITGB4	P17252	PRKCA	S99	R97W	97	Missense	proximal	-2	no	18.291	16.294	EPSD	ICGC;COSMIC	16.704	Loss
AGC_PKC_PKCa_PRKCA_ST	P16144	ITGB4	P17252	PRKCA	S99	R98H	98	Missense	proximal	-1	no	18.291	17.968	EPSD	ICGC;CCLE	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	P16144	ITGB4	P17252	PRKCA	S99	R98C	98	Missense	proximal	-1	no	18.291	15.631	EPSD	ICGC;COSMIC	16.704	Loss
AGC_PKC_PKCa_PRKCA_ST	P16144	ITGB4	P17252	PRKCA	S99	S102F	102	Missense	distal	3	no	18.291	17.779	EPSD	ICGC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	P16144	ITGB4	P17252	PRKCA	S102	R109H	109	Missense	distal	7	no	18.480	18.409	EPSD	ICGC;COSMIC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	P16144	ITGB4	P17252	PRKCA	S102	R97W	97	Missense	distal	-5	no	18.480	18.166	EPSD	ICGC;COSMIC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	P16144	ITGB4	P17252	PRKCA	S102	R98H	98	Missense	distal	-4	no	18.480	17.906	EPSD	ICGC;CCLE	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	P16144	ITGB4	P17252	PRKCA	S102	R109C	109	Missense	distal	7	no	18.480	18.257	EPSD	ICGC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	P16144	ITGB4	P17252	PRKCA	S102	R98C	98	Missense	distal	-4	no	18.480	17.137	EPSD	ICGC;COSMIC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	P16144	ITGB4	P17252	PRKCA	S102	S102F	102	Missense	central	0	yes	18.480	0.000	EPSD	ICGC	16.704	Loss
AGC_PKC_PKCa_PRKCA_ST	P16144	ITGB4	P17252	PRKCA	S377	R373L	373	Missense	distal	-4	no	17.475	16.851	EPSD	ICGC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	P16144	ITGB4	P17252	PRKCA	S397	K392E	392	Missense	distal	-5	no	17.492	17.198	EPSD	ICGC;COSMIC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	P16144	ITGB4	P17252	PRKCA	S397	R402Q	402	Missense	distal	5	no	17.492	17.484	EPSD	ICGC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	P16144	ITGB4	P17252	PRKCA	S397	R402L	402	Missense	distal	5	no	17.492	17.160	EPSD	ICGC;COSMIC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	P16144	ITGB4	P17252	PRKCA	S397	G396W	396	Missense	proximal	-1	no	17.492	16.046	EPSD	ICGC	16.704	Loss
AGC_PKC_PKCa_PRKCA_ST	P16144	ITGB4	P17252	PRKCA	S397	T395N	395	Missense	proximal	-2	no	17.492	17.189	EPSD	ICGC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	P16144	ITGB4	P17252	PRKCA	S821	R826L	826	Missense	distal	5	no	17.361	17.029	EPSD	ICGC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	P16144	ITGB4	P17252	PRKCA	S821	R826H	826	Missense	distal	5	no	17.361	17.101	EPSD	ICGC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	P16144	ITGB4	P17252	PRKCA	S1118	P1121S	1121	Missense	distal	3	no	17.040	17.180	EPSD	ICGC	16.704	Up-regulation
AGC_PKC_PKCa_PRKCA_ST	P16144	ITGB4	P17252	PRKCA	S1140	H1144N	1144	Missense	distal	4	no	18.713	18.039	EPSD	ICGC;COSMIC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	P16144	ITGB4	P17252	PRKCA	T1297	P1293S	1293	Missense	distal	-4	no	18.072	18.244	EPSD	ICGC;COSMIC	16.704	Up-regulation
AGC_PKC_PKCa_PRKCA_ST	P16144	ITGB4	P17252	PRKCA	T1297	R1301C	1301	Missense	distal	4	no	18.072	16.671	EPSD	ICGC	16.704	Loss
AGC_PKC_PKCa_PRKCA_ST	P16144	ITGB4	P17252	PRKCA	T1297	R1295L	1295	Missense	proximal	-2	no	18.072	15.384	EPSD	ICGC	16.704	Loss
AGC_PKC_PKCa_PRKCA_ST	P16144	ITGB4	P17252	PRKCA	S1325	P1320L	1320	Missense	distal	-5	no	16.878	16.852	EPSD	ICGC;COSMIC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	P16144	ITGB4	P17252	PRKCA	S1360	S1366P	1366	Missense	distal	6	no	18.940	18.973	PhosphoSitePlus;EPSD	ICGC	16.704	Up-regulation
AGC_PKC_PKCa_PRKCA_ST	P16144	ITGB4	P17252	PRKCA	S1364	S1366P	1366	Missense	proximal	2	no	18.268	17.686	EPSD;PhosphoSitePlus	ICGC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	P16144	ITGB4	P17252	PRKCA	S1428	S1428L	1428	Missense	central	0	yes	17.700	0.000	EPSD	ICGC;COSMIC	16.704	Loss
AGC_PKC_PKCa_PRKCA_ST	Q8NER1	TRPV1	P17252	PRKCA	S117	S117N	117	Missense	central	0	yes	18.829	0.000	EPSD	ICGC	16.704	Loss
AGC_PKC_PKCa_PRKCA_ST	Q8NER1	TRPV1	P17252	PRKCA	S117	R116S	116	Missense	proximal	-1	no	18.829	18.441	EPSD	ICGC;COSMIC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	Q8NER1	TRPV1	P17252	PRKCA	S117	D114N	114	Missense	distal	-3	no	18.829	19.644	EPSD	ICGC;COSMIC	16.704	Up-regulation
AGC_PKC_PKCa_PRKCA_ST	Q8NER1	TRPV1	P17252	PRKCA	S117	A121V	121	Missense	distal	4	no	18.829	17.491	EPSD	ICGC;COSMIC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	Q8NER1	TRPV1	P17252	PRKCA	S117	R116K	116	Missense	proximal	-1	no	18.829	18.886	EPSD	ICGC;COSMIC	16.704	Up-regulation
AGC_PKC_PKCa_PRKCA_ST	Q8NER1	TRPV1	P17252	PRKCA	S117	R115H	115	Missense	proximal	-2	no	18.829	14.275	EPSD	ICGC;COSMIC;GDSC;CCLE	16.704	Loss
AGC_PKC_PKCa_PRKCA_ST	Q8NER1	TRPV1	P17252	PRKCA	S186	A193V	193	Missense	distal	7	no	18.027	17.973	EPSD	ICGC;COSMIC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	Q8NER1	TRPV1	P17252	PRKCA	S186	E189D	189	Missense	distal	3	no	18.027	17.541	EPSD	ICGC;COSMIC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	Q8NER1	TRPV1	P17252	PRKCA	S186	A181V	181	Missense	distal	-5	no	18.027	17.943	EPSD	ICGC;COSMIC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	Q8NER1	TRPV1	P17252	PRKCA	S186	R182W	182	Missense	distal	-4	no	18.027	17.201	EPSD	ICGC;COSMIC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	Q8NER1	TRPV1	P17252	PRKCA	S186	K188R	188	Missense	proximal	2	no	18.027	18.449	EPSD	ICGC;COSMIC	16.704	Up-regulation
AGC_PKC_PKCa_PRKCA_ST	Q8NER1	TRPV1	P17252	PRKCA	S186	K188N	188	Missense	proximal	2	no	18.027	13.078	EPSD	ICGC;COSMIC	16.704	Loss
AGC_PKC_PKCa_PRKCA_ST	Q8NER1	TRPV1	P17252	PRKCA	S186	A181T	181	Missense	distal	-5	no	18.027	18.408	EPSD	ICGC;COSMIC	16.704	Up-regulation
AGC_PKC_PKCa_PRKCA_ST	Q8NER1	TRPV1	P17252	PRKCA	S502	M503L	503	Missense	proximal	1	no	23.256	23.470	EPSD;PhosphoSitePlus	ICGC	16.704	Up-regulation
AGC_PKC_PKCa_PRKCA_ST	Q8NER1	TRPV1	P17252	PRKCA	S502	L497M	497	Missense	distal	-5	no	23.256	23.217	EPSD;PhosphoSitePlus	ICGC;COSMIC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	Q8NER1	TRPV1	P17252	PRKCA	T773	S775R	775	Missense	proximal	2	no	13.250	17.869	EPSD	ICGC;COSMIC	16.704	Gain
AGC_PKC_PKCa_PRKCA_ST	Q8NER1	TRPV1	P17252	PRKCA	S775	V770I	770	Missense	distal	-5	no	18.280	18.273	EPSD	ICGC;COSMIC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	Q8NER1	TRPV1	P17252	PRKCA	S775	R779W	779	Missense	distal	4	no	18.280	16.744	EPSD	ICGC;COSMIC;GDSC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	Q8NER1	TRPV1	P17252	PRKCA	S775	R772C	772	Missense	distal	-3	no	18.280	15.541	EPSD	ICGC	16.704	Loss
AGC_PKC_PKCa_PRKCA_ST	Q8NER1	TRPV1	P17252	PRKCA	S775	R782S	782	Missense	distal	7	no	18.280	18.234	EPSD	ICGC;COSMIC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	Q8NER1	TRPV1	P17252	PRKCA	S775	S775R	775	Missense	central	0	yes	18.280	0.000	EPSD	ICGC;COSMIC	16.704	Loss
AGC_PKC_PKCa_PRKCA_ST	Q8NER1	TRPV1	P17252	PRKCA	S775	S781I	781	Missense	distal	6	no	18.280	18.246	EPSD	ICGC;COSMIC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	Q8NER1	TRPV1	P17252	PRKCA	S775	S777P	777	Missense	proximal	2	no	18.280	17.697	EPSD	ICGC;COSMIC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	Q8NER1	TRPV1	P17252	PRKCA	S775	F776L	776	Missense	proximal	1	no	18.280	17.623	EPSD	ICGC;COSMIC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	Q8NER1	TRPV1	P17252	PRKCA	S775	R772H	772	Missense	distal	-3	no	18.280	14.424	EPSD	ICGC;COSMIC;CCLE	16.704	Loss
AGC_PKC_PKCa_PRKCA_ST	Q8NER1	TRPV1	P17252	PRKCA	S777	V770I	770	Missense	distal	-7	no	18.563	18.562	EPSD	ICGC;COSMIC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	Q8NER1	TRPV1	P17252	PRKCA	S777	R779W	779	Missense	proximal	2	no	18.563	13.123	EPSD	ICGC;COSMIC;GDSC	16.704	Loss
AGC_PKC_PKCa_PRKCA_ST	Q8NER1	TRPV1	P17252	PRKCA	S777	R772C	772	Missense	distal	-5	no	18.563	17.888	EPSD	ICGC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	Q8NER1	TRPV1	P17252	PRKCA	S777	R782S	782	Missense	distal	5	no	18.563	18.422	EPSD	ICGC;COSMIC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	Q8NER1	TRPV1	P17252	PRKCA	S777	S775R	775	Missense	proximal	-2	no	18.563	21.865	EPSD	ICGC;COSMIC	16.704	Up-regulation
AGC_PKC_PKCa_PRKCA_ST	Q8NER1	TRPV1	P17252	PRKCA	S777	S781I	781	Missense	distal	4	no	18.563	17.119	EPSD	ICGC;COSMIC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	Q8NER1	TRPV1	P17252	PRKCA	S777	S777P	777	Missense	central	0	yes	18.563	0.000	EPSD	ICGC;COSMIC	16.704	Loss
AGC_PKC_PKCa_PRKCA_ST	Q8NER1	TRPV1	P17252	PRKCA	S777	F776L	776	Missense	proximal	-1	no	18.563	18.851	EPSD	ICGC;COSMIC	16.704	Up-regulation
AGC_PKC_PKCa_PRKCA_ST	Q8NER1	TRPV1	P17252	PRKCA	S777	R772H	772	Missense	distal	-5	no	18.563	18.208	EPSD	ICGC;COSMIC;CCLE	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	Q8NER1	TRPV1	P17252	PRKCA	S780	R779W	779	Missense	proximal	-1	no	19.475	17.890	EPSD	ICGC;COSMIC;GDSC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	Q8NER1	TRPV1	P17252	PRKCA	S780	H787Q	787	Missense	distal	7	no	19.475	19.542	EPSD	ICGC	16.704	Up-regulation
AGC_PKC_PKCa_PRKCA_ST	Q8NER1	TRPV1	P17252	PRKCA	S780	R782S	782	Missense	proximal	2	no	19.475	14.855	EPSD	ICGC;COSMIC	16.704	Loss
AGC_PKC_PKCa_PRKCA_ST	Q8NER1	TRPV1	P17252	PRKCA	S780	S775R	775	Missense	distal	-5	no	19.475	19.902	EPSD	ICGC;COSMIC	16.704	Up-regulation
AGC_PKC_PKCa_PRKCA_ST	Q8NER1	TRPV1	P17252	PRKCA	S780	S781I	781	Missense	proximal	1	no	19.475	21.138	EPSD	ICGC;COSMIC	16.704	Up-regulation
AGC_PKC_PKCa_PRKCA_ST	Q8NER1	TRPV1	P17252	PRKCA	S780	S777P	777	Missense	distal	-3	no	19.475	18.497	EPSD	ICGC;COSMIC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	Q8NER1	TRPV1	P17252	PRKCA	S780	F776L	776	Missense	distal	-4	no	19.475	19.102	EPSD	ICGC;COSMIC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	Q8NER1	TRPV1	P17252	PRKCA	S784	R779W	779	Missense	distal	-5	no	20.212	19.898	EPSD	ICGC;COSMIC;GDSC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	Q8NER1	TRPV1	P17252	PRKCA	S784	K789N	789	Missense	distal	5	no	20.212	19.706	EPSD	ICGC;COSMIC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	Q8NER1	TRPV1	P17252	PRKCA	S784	H787Q	787	Missense	distal	3	no	20.212	18.471	EPSD	ICGC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	Q8NER1	TRPV1	P17252	PRKCA	S784	W788L	788	Missense	distal	4	no	20.212	20.710	EPSD	ICGC;COSMIC	16.704	Up-regulation
AGC_PKC_PKCa_PRKCA_ST	Q8NER1	TRPV1	P17252	PRKCA	S784	R782S	782	Missense	proximal	-2	no	20.212	16.910	EPSD	ICGC;COSMIC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	Q8NER1	TRPV1	P17252	PRKCA	S784	S781I	781	Missense	distal	-3	no	20.212	18.595	EPSD	ICGC;COSMIC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	Q8NER1	TRPV1	P17252	PRKCA	S784	S777P	777	Missense	distal	-7	no	20.212	20.209	EPSD	ICGC;COSMIC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	Q8NER1	TRPV1	P17252	PRKCA	S801	Q806K	806	Missense	distal	5	no	20.241	20.394	PhosphoSitePlus;EPSD	ICGC	16.704	Up-regulation
AGC_PKC_PKCa_PRKCA_ST	Q8NER1	TRPV1	P17252	PRKCA	S801	A808D	808	Missense	distal	7	no	20.241	20.246	PhosphoSitePlus;EPSD	ICGC;COSMIC	16.704	Up-regulation
AGC_PKC_PKCa_PRKCA_ST	Q8NER1	TRPV1	P17252	PRKCA	S801	A808V	808	Missense	distal	7	no	20.241	20.187	PhosphoSitePlus;EPSD	ICGC;COSMIC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	Q8NER1	TRPV1	P17252	PRKCA	S807	Q806K	806	Missense	proximal	-1	no	16.568	17.443	EPSD	ICGC	16.704	Gain
AGC_PKC_PKCa_PRKCA_ST	Q8NER1	TRPV1	P17252	PRKCA	S807	Q809R	809	Missense	proximal	2	no	16.568	20.402	EPSD	ICGC;COSMIC	16.704	Gain
AGC_PKC_PKCa_PRKCA_ST	Q8NER1	TRPV1	P17252	PRKCA	S807	A808V	808	Missense	proximal	1	no	16.568	16.721	EPSD	ICGC;COSMIC	16.704	Gain
AGC_PKC_PKCa_PRKCA_ST	Q8NER1	TRPV1	P17252	PRKCA	S821	S819L	819	Missense	proximal	-2	no	16.924	17.537	EPSD	ICGC	16.704	Up-regulation
AGC_PKC_PKCa_PRKCA_ST	Q8NER1	TRPV1	P17252	PRKCA	S821	A827D	827	Missense	distal	6	no	16.924	16.876	EPSD	ICGC;COSMIC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	P08684	CYP3A4	P17252	PRKCA	T103	P107S	107	Missense	distal	4	no	16.840	17.040	EPSD;PhosphoSitePlus	ICGC;GDSC	16.704	Up-regulation
AGC_PKC_PKCa_PRKCA_ST	P08684	CYP3A4	P17252	PRKCA	T103	S100Y	100	Missense	distal	-3	no	16.840	15.150	EPSD;PhosphoSitePlus	ICGC;COSMIC	16.704	Loss
AGC_PKC_PKCa_PRKCA_ST	P08684	CYP3A4	P17252	PRKCA	T103	P110Q	110	Missense	distal	7	no	16.840	16.846	EPSD;PhosphoSitePlus	ICGC;COSMIC	16.704	Up-regulation
AGC_PKC_PKCa_PRKCA_ST	P08684	CYP3A4	P17252	PRKCA	S131	R128I	128	Missense	distal	-3	no	19.379	14.892	EPSD;PhosphoSitePlus	ICGC;COSMIC	16.704	Loss
AGC_PKC_PKCa_PRKCA_ST	P08684	CYP3A4	P17252	PRKCA	S131	R130Q	130	Missense	proximal	-1	no	19.379	18.562	EPSD;PhosphoSitePlus	ICGC;COSMIC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	P08684	CYP3A4	P17252	PRKCA	S131	T136A	136	Missense	distal	5	no	19.379	19.658	EPSD;PhosphoSitePlus	ICGC	16.704	Up-regulation
AGC_PKC_PKCa_PRKCA_ST	P08684	CYP3A4	P17252	PRKCA	S259	E262D	262	Missense	distal	3	no	17.083	16.596	EPSD;PhosphoSitePlus	ICGC;COSMIC	16.704	Loss
AGC_PKC_PKCa_PRKCA_ST	P08684	CYP3A4	P17252	PRKCA	T264	E262D	262	Missense	proximal	-2	no	16.001	16.709	EPSD;PhosphoSitePlus	ICGC;COSMIC	16.704	Gain
AGC_PKC_PKCa_PRKCA_ST	P24844	MYL9	P17252	PRKCA	S2	R5Q	5	Missense	distal	3	no	23.201	20.748	EPSD;PhosphoSitePlus	ICGC;COSMIC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	P24844	MYL9	P17252	PRKCA	S3	R5Q	5	Missense	proximal	2	no	21.575	17.741	EPSD;PhosphoSitePlus	ICGC;COSMIC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	P24844	MYL9	P17252	PRKCA	T10	R17L	17	Missense	distal	7	no	22.937	22.894	PhosphoSitePlus;EPSD	ICGC;COSMIC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	P24844	MYL9	P17252	PRKCA	T10	R5Q	5	Missense	distal	-5	no	22.937	22.785	PhosphoSitePlus;EPSD	ICGC;COSMIC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	P24844	MYL9	P17252	PRKCA	T10	R14W	14	Missense	distal	4	no	22.937	21.401	PhosphoSitePlus;EPSD	ICGC;COSMIC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	P24844	MYL9	P17252	PRKCA	T11	R17L	17	Missense	distal	6	no	20.429	20.347	EPSD	ICGC;COSMIC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	P24844	MYL9	P17252	PRKCA	T11	R5Q	5	Missense	distal	-6	no	20.429	20.286	EPSD	ICGC;COSMIC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	P24844	MYL9	P17252	PRKCA	T11	R14W	14	Missense	distal	3	no	20.429	17.496	EPSD	ICGC;COSMIC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	P24844	MYL9	P17252	PRKCA	S20	R17L	17	Missense	distal	-3	no	17.126	12.770	EPSD	ICGC;COSMIC	16.704	Loss
AGC_PKC_PKCa_PRKCA_ST	P24844	MYL9	P17252	PRKCA	S20	R14W	14	Missense	distal	-6	no	17.126	16.841	EPSD	ICGC;COSMIC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	P19174	PLCG1	P17252	PRKCA	S40	T36P	36	Missense	distal	-4	no	16.455	16.945	EPSD	ICGC;COSMIC	16.704	Gain
AGC_PKC_PKCa_PRKCA_ST	P19174	PLCG1	P17252	PRKCA	S43	K41N	41	Missense	proximal	-2	no	21.844	20.275	EPSD	ICGC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	P19174	PLCG1	P17252	PRKCA	S43	R48L	48	Missense	distal	5	no	21.844	21.512	EPSD	ICGC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	P19174	PLCG1	P17252	PRKCA	S43	T50N	50	Missense	distal	7	no	21.844	21.813	EPSD	ICGC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	P19174	PLCG1	P17252	PRKCA	S43	T36P	36	Missense	distal	-7	no	21.844	21.843	EPSD	ICGC;COSMIC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	P19174	PLCG1	P17252	PRKCA	S705	R707Q	707	Missense	proximal	2	no	17.670	13.836	EPSD	ICGC;COSMIC	16.704	Loss
AGC_PKC_PKCa_PRKCA_ST	P19174	PLCG1	P17252	PRKCA	S705	A703V	703	Missense	proximal	-2	no	17.670	17.914	EPSD	ICGC;COSMIC	16.704	Up-regulation
AGC_PKC_PKCa_PRKCA_ST	P19174	PLCG1	P17252	PRKCA	S1227	R1229Q	1229	Missense	proximal	2	no	19.297	15.463	EPSD	ICGC;COSMIC	16.704	Loss
AGC_PKC_PKCa_PRKCA_ST	P19174	PLCG1	P17252	PRKCA	S1227	R1231L	1231	Missense	distal	4	no	19.297	18.259	EPSD	ICGC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	P19174	PLCG1	P17252	PRKCA	S1227	G1225V	1225	Missense	proximal	-2	no	19.297	19.328	EPSD	ICGC	16.704	Up-regulation
AGC_PKC_PKCa_PRKCA_ST	P19174	PLCG1	P17252	PRKCA	S1227	L1220R	1220	Missense	distal	-7	no	19.297	19.308	EPSD	ICGC;COSMIC	16.704	Up-regulation
AGC_PKC_PKCa_PRKCA_ST	P19174	PLCG1	P17252	PRKCA	S1248	R1252H	1252	Missense	distal	4	no	19.739	19.457	PhosphoSitePlus	ICGC;COSMIC;CCLE	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	P19174	PLCG1	P17252	PRKCA	S1248	R1245W	1245	Missense	distal	-3	no	19.739	17.385	PhosphoSitePlus	ICGC;COSMIC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	P19174	PLCG1	P17252	PRKCA	S1248	Q1255K	1255	Missense	distal	7	no	19.739	19.794	PhosphoSitePlus	ICGC;COSMIC	16.704	Up-regulation
AGC_PKC_PKCa_PRKCA_ST	P19174	PLCG1	P17252	PRKCA	S1263	E1265K	1265	Missense	proximal	2	no	15.036	20.315	EPSD	ICGC	16.704	Gain
AGC_PKC_PKCa_PRKCA_ST	P10636	MAPT	P17252	PRKCA	S171	R164T	164	Missense	distal	-7	no	19.508	19.500	EPSD	ICGC;COSMIC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	P10636	MAPT	P17252	PRKCA	S171	A166T	166	Missense	distal	-5	no	19.508	19.889	EPSD	ICGC	16.704	Up-regulation
AGC_PKC_PKCa_PRKCA_ST	P10636	MAPT	P17252	PRKCA	S447	Y441H	441	Missense	distal	-6	no	17.139	17.198	EPSD	ICGC;COSMIC	16.704	Up-regulation
AGC_PKC_PKCa_PRKCA_ST	P10636	MAPT	P17252	PRKCA	S519	G521R	521	Missense	proximal	2	no	13.263	18.508	EPSD	ICGC;COSMIC	16.704	Gain
AGC_PKC_PKCa_PRKCA_ST	O75689	ADAP1	P17252	PRKCA	S204	R206H	206	Missense	proximal	2	no	16.922	11.898	EPSD	ICGC;CCLE	16.704	Loss
AGC_PKC_PKCa_PRKCA_ST	P31645	SLC6A4	P17252	PRKCA	S40	Q42K	42	Missense	proximal	2	no	14.041	17.454	EPSD	ICGC;COSMIC	16.704	Gain
AGC_PKC_PKCa_PRKCA_ST	P31645	SLC6A4	P17252	PRKCA	S277	V274I	274	Missense	distal	-3	no	17.966	17.168	EPSD;PhosphoSitePlus	ICGC;COSMIC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	P31645	SLC6A4	P17252	PRKCA	S277	G278S	278	Missense	proximal	1	no	17.966	17.745	EPSD;PhosphoSitePlus	ICGC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	P31645	SLC6A4	P17252	PRKCA	S277	W282L	282	Missense	distal	5	no	17.966	18.142	EPSD;PhosphoSitePlus	ICGC;COSMIC	16.704	Up-regulation
AGC_PKC_PKCa_PRKCA_ST	P31645	SLC6A4	P17252	PRKCA	S277	V280M	280	Missense	distal	3	no	17.966	18.552	EPSD;PhosphoSitePlus	ICGC	16.704	Up-regulation
AGC_PKC_PKCa_PRKCA_ST	P05107	ITGB2	P17252	PRKCA	T118	R121L	121	Missense	distal	3	no	19.005	16.767	EPSD	ICGC;COSMIC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	P05107	ITGB2	P17252	PRKCA	S490	S489R	489	Missense	proximal	-1	no	16.585	16.972	EPSD	ICGC	16.704	Gain
AGC_PKC_PKCa_PRKCA_ST	P05107	ITGB2	P17252	PRKCA	S496	S496R	496	Missense	central	0	yes	17.597	0.000	EPSD	ICGC	16.704	Loss
AGC_PKC_PKCa_PRKCA_ST	P05107	ITGB2	P17252	PRKCA	S496	S489R	489	Missense	distal	-7	no	17.597	17.602	EPSD	ICGC	16.704	Up-regulation
AGC_PKC_PKCa_PRKCA_ST	P19086	GNAZ	P17252	PRKCA	S16	H22L	22	Missense	distal	6	no	23.083	23.078	PhosphoSitePlus;EPSD	ICGC;COSMIC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	P19086	GNAZ	P17252	PRKCA	S16	R14L	14	Missense	proximal	-2	no	23.083	20.395	PhosphoSitePlus;EPSD	ICGC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	P19086	GNAZ	P17252	PRKCA	S16	S16F	16	Missense	central	0	yes	23.083	0.000	PhosphoSitePlus;EPSD	ICGC	16.704	Loss
AGC_PKC_PKCa_PRKCA_ST	P19086	GNAZ	P17252	PRKCA	S16	A13S	13	Missense	distal	-3	no	23.083	24.661	PhosphoSitePlus;EPSD	ICGC;COSMIC	16.704	Up-regulation
AGC_PKC_PKCa_PRKCA_ST	P19086	GNAZ	P17252	PRKCA	S27	E33K	33	Missense	distal	6	no	21.195	21.289	EPSD;PhosphoSitePlus	ICGC;COSMIC	16.704	Up-regulation
AGC_PKC_PKCa_PRKCA_ST	P19086	GNAZ	P17252	PRKCA	S27	H22L	22	Missense	distal	-5	no	21.195	21.422	EPSD;PhosphoSitePlus	ICGC;COSMIC	16.704	Up-regulation
AGC_PKC_PKCa_PRKCA_ST	O60941	DTNB	P17252	PRKCA	T11	N7K	7	Missense	distal	-4	no	19.127	19.686	EPSD	ICGC;COSMIC	16.704	Up-regulation
AGC_PKC_PKCa_PRKCA_ST	O60941	DTNB	P17252	PRKCA	S497	R495M	495	Missense	proximal	-2	no	16.796	14.815	EPSD	ICGC;COSMIC	16.704	Loss
AGC_PKC_PKCa_PRKCA_ST	O60941	DTNB	P17252	PRKCA	S502	R495M	495	Missense	distal	-7	no	18.707	18.704	EPSD	ICGC;COSMIC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	O60941	DTNB	P17252	PRKCA	T580	A575S	575	Missense	distal	-5	no	17.204	17.257	EPSD	ICGC;COSMIC	16.704	Up-regulation
AGC_PKC_PKCa_PRKCA_ST	O60941	DTNB	P17252	PRKCA	T580	D587E	587	Missense	distal	7	no	17.204	17.152	EPSD	ICGC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	Q9UKG1	APPL1	P17252	PRKCA	S427	G432R	432	Missense	distal	5	no	16.780	17.062	EPSD	ICGC;COSMIC	16.704	Up-regulation
AGC_PKC_PKCa_PRKCA_ST	Q9UKG1	APPL1	P17252	PRKCA	S430	G432R	432	Missense	proximal	2	no	14.412	19.658	PhosphoSitePlus	ICGC;COSMIC	16.704	Gain
AGC_PKC_PKCa_PRKCA_ST	Q9UKG1	APPL1	P17252	PRKCA	S488	E494K	494	Missense	distal	6	no	18.651	18.745	EPSD	ICGC;COSMIC	16.704	Up-regulation
AGC_PKC_PKCa_PRKCA_ST	Q9UKG1	APPL1	P17252	PRKCA	S488	T493S	493	Missense	distal	5	no	18.651	18.826	EPSD	ICGC	16.704	Up-regulation
AGC_PKC_PKCa_PRKCA_ST	Q9UKG1	APPL1	P17252	PRKCA	S591	L588F	588	Missense	distal	-3	no	15.307	17.042	EPSD	ICGC	16.704	Gain
AGC_PKC_PKCa_PRKCA_ST	Q9UKG1	APPL1	P17252	PRKCA	S592	R589L	589	Missense	distal	-3	no	21.410	17.055	EPSD	ICGC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	Q9UKG1	APPL1	P17252	PRKCA	S592	L588F	588	Missense	distal	-4	no	21.410	21.783	EPSD	ICGC	16.704	Up-regulation
AGC_PKC_PKCa_PRKCA_ST	P04626	ERBB2	P17252	PRKCA	S760	A763T	763	Missense	distal	3	no	17.279	17.040	EPSD	ICGC;COSMIC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	O14493	CLDN4	P17252	PRKCA	S194	S198P	198	Missense	distal	4	no	17.231	17.031	PhosphoSitePlus	ICGC;COSMIC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	O14493	CLDN4	P17252	PRKCA	S194	A195T	195	Missense	proximal	1	no	17.231	16.760	PhosphoSitePlus	ICGC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	P08253	MMP2	P17252	PRKCA	S160	D153N	153	Missense	distal	-7	no	16.872	16.871	EPSD;PhosphoSitePlus	ICGC;COSMIC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	P08253	MMP2	P17252	PRKCA	S160	D153Y	153	Missense	distal	-7	no	16.872	16.876	EPSD;PhosphoSitePlus	ICGC	16.704	Up-regulation
AGC_PKC_PKCa_PRKCA_ST	P08253	MMP2	P17252	PRKCA	S160	G165V	165	Missense	distal	5	no	16.872	16.731	EPSD;PhosphoSitePlus	ICGC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	P21730	C5AR1	P17252	PRKCA	S314	R312W	312	Missense	proximal	-2	no	17.842	15.844	PhosphoSitePlus;EPSD	ICGC;COSMIC	16.704	Loss
AGC_PKC_PKCa_PRKCA_ST	Q9H3Q1	CDC42EP4	P17252	PRKCA	S9	S11L	11	Missense	proximal	2	no	17.716	17.349	EPSD	ICGC;COSMIC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	Q9H3Q1	CDC42EP4	P17252	PRKCA	S10	S11L	11	Missense	proximal	1	no	17.706	18.532	EPSD	ICGC;COSMIC	16.704	Up-regulation
AGC_PKC_PKCa_PRKCA_ST	Q9H3Q1	CDC42EP4	P17252	PRKCA	S11	S11L	11	Missense	central	0	yes	17.583	0.000	EPSD	ICGC;COSMIC	16.704	Loss
AGC_PKC_PKCa_PRKCA_ST	Q9H3Q1	CDC42EP4	P17252	PRKCA	S14	A20E	20	Missense	distal	6	no	25.078	25.013	EPSD	ICGC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	Q9H3Q1	CDC42EP4	P17252	PRKCA	S14	D21G	21	Missense	distal	7	no	25.078	25.097	EPSD	ICGC;COSMIC	16.704	Up-regulation
AGC_PKC_PKCa_PRKCA_ST	Q9H3Q1	CDC42EP4	P17252	PRKCA	S14	S11L	11	Missense	distal	-3	no	25.078	23.592	EPSD	ICGC;COSMIC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	Q9H3Q1	CDC42EP4	P17252	PRKCA	S14	R19Q	19	Missense	distal	5	no	25.078	25.070	EPSD	ICGC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	Q9H3Q1	CDC42EP4	P17252	PRKCA	S18	A20E	20	Missense	proximal	2	no	19.773	18.771	PhosphoSitePlus;EPSD	ICGC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	Q9H3Q1	CDC42EP4	P17252	PRKCA	S18	D21G	21	Missense	distal	3	no	19.773	20.858	PhosphoSitePlus;EPSD	ICGC;COSMIC	16.704	Up-regulation
AGC_PKC_PKCa_PRKCA_ST	Q9H3Q1	CDC42EP4	P17252	PRKCA	S18	S11L	11	Missense	distal	-7	no	19.773	19.767	PhosphoSitePlus;EPSD	ICGC;COSMIC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	Q9H3Q1	CDC42EP4	P17252	PRKCA	S18	R19Q	19	Missense	proximal	1	no	19.773	19.656	PhosphoSitePlus;EPSD	ICGC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	Q9H3Q1	CDC42EP4	P17252	PRKCA	S73	R76C	76	Missense	distal	3	no	20.992	18.374	EPSD	ICGC;COSMIC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	Q9H3Q1	CDC42EP4	P17252	PRKCA	S74	R76C	76	Missense	proximal	2	no	19.377	15.026	EPSD	ICGC;COSMIC	16.704	Loss
AGC_PKC_PKCa_PRKCA_ST	Q9H3Q1	CDC42EP4	P17252	PRKCA	S77	R76C	76	Missense	proximal	-1	no	18.331	15.672	EPSD	ICGC;COSMIC	16.704	Loss
AGC_PKC_PKCa_PRKCA_ST	Q9H3Q1	CDC42EP4	P17252	PRKCA	S80	R76C	76	Missense	distal	-4	no	20.408	19.065	EPSD;PhosphoSitePlus	ICGC;COSMIC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	Q9H3Q1	CDC42EP4	P17252	PRKCA	S91	R97Q	97	Missense	distal	6	no	17.474	17.352	EPSD	ICGC;COSMIC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	Q9H3Q1	CDC42EP4	P17252	PRKCA	S105	R107L	107	Missense	proximal	2	no	19.370	14.383	EPSD	ICGC;COSMIC	16.704	Loss
AGC_PKC_PKCa_PRKCA_ST	Q9H3Q1	CDC42EP4	P17252	PRKCA	S105	M102I	102	Missense	distal	-3	no	19.370	17.854	EPSD	ICGC;COSMIC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	Q9H3Q1	CDC42EP4	P17252	PRKCA	S295	A289E	289	Missense	distal	-6	no	18.309	18.345	EPSD	ICGC	16.704	Up-regulation
AGC_PKC_PKCa_PRKCA_ST	Q07954	LRP1	P17252	PRKCA	S508	T503P	503	Missense	distal	-5	no	18.650	18.647	EPSD	ICGC;COSMIC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	Q07954	LRP1	P17252	PRKCA	S1878	M1872I	1872	Missense	distal	-6	no	17.142	17.048	EPSD	ICGC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	Q07954	LRP1	P17252	PRKCA	S1997	G1996D	1996	Missense	proximal	-1	no	16.987	16.243	EPSD	ICGC;COSMIC	16.704	Loss
AGC_PKC_PKCa_PRKCA_ST	Q07954	LRP1	P17252	PRKCA	S1997	Y2000C	2000	Missense	distal	3	no	16.987	16.636	EPSD	ICGC	16.704	Loss
AGC_PKC_PKCa_PRKCA_ST	Q07954	LRP1	P17252	PRKCA	S2563	C2566S	2566	Missense	distal	3	no	19.367	20.594	EPSD	ICGC;COSMIC	16.704	Up-regulation
AGC_PKC_PKCa_PRKCA_ST	Q07954	LRP1	P17252	PRKCA	S2563	R2565L	2565	Missense	proximal	2	no	19.367	14.380	EPSD	ICGC;COSMIC	16.704	Loss
AGC_PKC_PKCa_PRKCA_ST	Q07954	LRP1	P17252	PRKCA	S2563	R2564S	2564	Missense	proximal	1	no	19.367	18.193	EPSD	ICGC;COSMIC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	Q07954	LRP1	P17252	PRKCA	S2563	S2563Y	2563	Missense	central	0	yes	19.367	0.000	EPSD	ICGC;COSMIC	16.704	Loss
AGC_PKC_PKCa_PRKCA_ST	Q07954	LRP1	P17252	PRKCA	S2950	L2945H	2945	Missense	distal	-5	no	16.788	16.560	EPSD	ICGC;COSMIC	16.704	Loss
AGC_PKC_PKCa_PRKCA_ST	Q07954	LRP1	P17252	PRKCA	S2950	S2946R	2946	Missense	distal	-4	no	16.788	16.981	EPSD	ICGC;COSMIC	16.704	Up-regulation
AGC_PKC_PKCa_PRKCA_ST	Q07954	LRP1	P17252	PRKCA	S2950	R2947H	2947	Missense	distal	-3	no	16.788	12.931	EPSD	ICGC	16.704	Loss
AGC_PKC_PKCa_PRKCA_ST	Q07954	LRP1	P17252	PRKCA	S3938	R3942W	3942	Missense	distal	4	no	19.086	17.550	EPSD	ICGC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	Q07954	LRP1	P17252	PRKCA	T4034	T4028M	4028	Missense	distal	-6	no	17.363	17.486	EPSD	ICGC;COSMIC	16.704	Up-regulation
AGC_PKC_PKCa_PRKCA_ST	Q07954	LRP1	P17252	PRKCA	T4034	R4036Q	4036	Missense	proximal	2	no	17.363	13.529	EPSD	ICGC	16.704	Loss
AGC_PKC_PKCa_PRKCA_ST	Q07954	LRP1	P17252	PRKCA	T4034	R4036L	4036	Missense	proximal	2	no	17.363	12.376	EPSD	ICGC;COSMIC	16.704	Loss
AGC_PKC_PKCa_PRKCA_ST	Q07954	LRP1	P17252	PRKCA	S4071	K4065R	4065	Missense	distal	-6	no	18.278	18.285	EPSD	ICGC;COSMIC	16.704	Up-regulation
AGC_PKC_PKCa_PRKCA_ST	Q07954	LRP1	P17252	PRKCA	S4071	K4065N	4065	Missense	distal	-6	no	18.278	18.155	EPSD	ICGC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	Q07954	LRP1	P17252	PRKCA	S4520	S4523R	4523	Missense	distal	3	no	15.712	17.103	PhosphoSitePlus;EPSD	ICGC;COSMIC	16.704	Gain
AGC_PKC_PKCa_PRKCA_ST	P52565	ARHGDIA	P17252	PRKCA	S47	R49Q	49	Missense	proximal	2	no	17.169	13.334	EPSD	ICGC;COSMIC	16.704	Loss
AGC_PKC_PKCa_PRKCA_ST	P52565	ARHGDIA	P17252	PRKCA	S47	E53K	53	Missense	distal	6	no	17.169	17.263	EPSD	ICGC;CCLE	16.704	Up-regulation
AGC_PKC_PKCa_PRKCA_ST	P52565	ARHGDIA	P17252	PRKCA	S47	E46K	46	Missense	proximal	-1	no	17.169	17.595	EPSD	ICGC;COSMIC	16.704	Up-regulation
AGC_PKC_PKCa_PRKCA_ST	P52565	ARHGDIA	P17252	PRKCA	S96	T91P	91	Missense	distal	-5	no	20.335	20.333	EPSD;PhosphoSitePlus	ICGC;COSMIC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	P53004	BLVRA	P17252	PRKCA	S21	R28W	28	Missense	distal	7	no	24.825	24.645	EPSD	ICGC;COSMIC;GDSC;CCLE	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	P53004	BLVRA	P17252	PRKCA	S21	G15D	15	Missense	distal	-6	no	24.825	24.775	EPSD	ICGC;COSMIC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	P53004	BLVRA	P17252	PRKCA	S21	G15V	15	Missense	distal	-6	no	24.825	24.746	EPSD	ICGC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	P53004	BLVRA	P17252	PRKCA	T207	E206Q	206	Missense	proximal	-1	no	18.781	18.332	EPSD	ICGC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	P53004	BLVRA	P17252	PRKCA	T207	S214L	214	Missense	distal	7	no	18.781	18.784	EPSD	ICGC;COSMIC	16.704	Up-regulation
AGC_PKC_PKCa_PRKCA_ST	P53004	BLVRA	P17252	PRKCA	S230	S235T	235	Missense	distal	5	no	19.508	19.333	PhosphoSitePlus;EPSD	ICGC;COSMIC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	P19429	TNNI3	P17252	PRKCA	S23	R27S	27	Missense	distal	4	no	20.612	20.366	EPSD;PhosphoSitePlus	ICGC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	P19429	TNNI3	P17252	PRKCA	S23	R21S	21	Missense	proximal	-2	no	20.612	17.310	EPSD;PhosphoSitePlus	ICGC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	P19429	TNNI3	P17252	PRKCA	S23	S24F	24	Missense	proximal	1	no	20.612	22.096	EPSD;PhosphoSitePlus	ICGC;COSMIC	16.704	Up-regulation
AGC_PKC_PKCa_PRKCA_ST	P19429	TNNI3	P17252	PRKCA	S23	R21L	21	Missense	proximal	-2	no	20.612	17.924	EPSD;PhosphoSitePlus	ICGC;COSMIC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	P19429	TNNI3	P17252	PRKCA	S24	R27S	27	Missense	distal	3	no	23.700	22.309	EPSD;PhosphoSitePlus	ICGC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	P19429	TNNI3	P17252	PRKCA	S24	R21S	21	Missense	distal	-3	no	23.700	20.830	EPSD;PhosphoSitePlus	ICGC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	P19429	TNNI3	P17252	PRKCA	S24	S24F	24	Missense	central	0	yes	23.700	0.000	EPSD;PhosphoSitePlus	ICGC;COSMIC	16.704	Loss
AGC_PKC_PKCa_PRKCA_ST	P19429	TNNI3	P17252	PRKCA	S24	R21L	21	Missense	distal	-3	no	23.700	19.344	EPSD;PhosphoSitePlus	ICGC;COSMIC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	P19429	TNNI3	P17252	PRKCA	S39	P33Q	33	Missense	distal	-6	no	19.795	19.756	EPSD	ICGC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	P19429	TNNI3	P17252	PRKCA	T143	R145W	145	Missense	proximal	2	no	21.018	15.578	EPSD;PhosphoSitePlus	ICGC;COSMIC;GDSC;CCLE	16.704	Loss
AGC_PKC_PKCa_PRKCA_ST	P08183	ABCB1	P17252	PRKCA	S661	D657N	657	Missense	distal	-4	no	20.128	20.477	PhosphoSitePlus;EPSD	ICGC	16.704	Up-regulation
AGC_PKC_PKCa_PRKCA_ST	P08183	ABCB1	P17252	PRKCA	S667	R673H	673	Missense	distal	6	no	24.429	24.352	EPSD;PhosphoSitePlus	ICGC;COSMIC;GDSC;CCLE	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	P08183	ABCB1	P17252	PRKCA	S667	R669C	669	Missense	proximal	2	no	24.429	20.079	EPSD;PhosphoSitePlus	ICGC;COSMIC;GDSC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	P08183	ABCB1	P17252	PRKCA	S667	R673C	673	Missense	distal	6	no	24.429	24.190	EPSD;PhosphoSitePlus	ICGC;COSMIC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	P08183	ABCB1	P17252	PRKCA	S671	R673H	673	Missense	proximal	2	no	22.872	17.849	EPSD;PhosphoSitePlus	ICGC;COSMIC;GDSC;CCLE	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	P08183	ABCB1	P17252	PRKCA	S671	R669C	669	Missense	proximal	-2	no	22.872	21.172	EPSD;PhosphoSitePlus	ICGC;COSMIC;GDSC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	P08183	ABCB1	P17252	PRKCA	S671	R673C	673	Missense	proximal	2	no	22.872	18.522	EPSD;PhosphoSitePlus	ICGC;COSMIC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	P08183	ABCB1	P17252	PRKCA	S675	R673H	673	Missense	proximal	-2	no	18.840	14.287	EPSD	ICGC;COSMIC;GDSC;CCLE	16.704	Loss
AGC_PKC_PKCa_PRKCA_ST	P08183	ABCB1	P17252	PRKCA	S675	R669C	669	Missense	distal	-6	no	18.840	18.471	EPSD	ICGC;COSMIC;GDSC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	P08183	ABCB1	P17252	PRKCA	S675	R680K	680	Missense	distal	5	no	18.840	18.984	EPSD	ICGC;COSMIC	16.704	Up-regulation
AGC_PKC_PKCa_PRKCA_ST	P08183	ABCB1	P17252	PRKCA	S675	R673C	673	Missense	proximal	-2	no	18.840	17.140	EPSD	ICGC;COSMIC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	P08183	ABCB1	P17252	PRKCA	S683	R680K	680	Missense	distal	-3	no	22.617	20.591	EPSD	ICGC;COSMIC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	P08183	ABCB1	P17252	PRKCA	S683	E690K	690	Missense	distal	7	no	22.617	22.763	EPSD	ICGC	16.704	Up-regulation
AGC_PKC_PKCa_PRKCA_ST	P08183	ABCB1	P17252	PRKCA	S683	D689Y	689	Missense	distal	6	no	22.617	22.654	EPSD	ICGC;COSMIC	16.704	Up-regulation
AGC_PKC_PKCa_PRKCA_ST	O14745	SLC9A3R1	P17252	PRKCA	S77	V76L	76	Missense	proximal	-1	no	16.912	17.955	EPSD;PhosphoSitePlus	ICGC	16.704	Up-regulation
AGC_PKC_PKCa_PRKCA_ST	O14745	SLC9A3R1	P17252	PRKCA	T156	R151L	151	Missense	distal	-5	no	17.300	17.173	EPSD	ICGC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	O14745	SLC9A3R1	P17252	PRKCA	T156	P152S	152	Missense	distal	-4	no	17.300	17.472	EPSD	ICGC;COSMIC	16.704	Up-regulation
AGC_PKC_PKCa_PRKCA_ST	O14745	SLC9A3R1	P17252	PRKCA	S280	L273P	273	Missense	distal	-7	no	17.370	17.373	EPSD	ICGC;COSMIC	16.704	Up-regulation
AGC_PKC_PKCa_PRKCA_ST	O14745	SLC9A3R1	P17252	PRKCA	S339	R338H	338	Missense	proximal	-1	no	19.714	19.391	EPSD;PhosphoSitePlus	ICGC;COSMIC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	O14745	SLC9A3R1	P17252	PRKCA	S340	D347N	347	Missense	distal	7	no	21.773	21.746	PhosphoSitePlus;EPSD	ICGC;COSMIC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	O14745	SLC9A3R1	P17252	PRKCA	S340	R338H	338	Missense	proximal	-2	no	21.773	17.219	PhosphoSitePlus;EPSD	ICGC;COSMIC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	Q96RI1	NR1H4	P17252	PRKCA	S31	A35V	35	Missense	distal	4	no	18.330	16.992	EPSD	ICGC;COSMIC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	Q96RI1	NR1H4	P17252	PRKCA	S164	N168S	168	Missense	distal	4	no	21.279	21.989	EPSD	ICGC;COSMIC	16.704	Up-regulation
AGC_PKC_PKCa_PRKCA_ST	P78536	ADAM17	P17252	PRKCA	S608	P613T	613	Missense	distal	5	no	18.266	17.931	EPSD	ICGC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	P78536	ADAM17	P17252	PRKCA	T761	L754M	754	Missense	distal	-7	no	17.286	17.294	EPSD	ICGC;COSMIC	16.704	Up-regulation
AGC_PKC_PKCa_PRKCA_ST	O95243	MBD4	P17252	PRKCA	S8	T3K	3	Missense	distal	-5	no	16.618	16.705	EPSD	ICGC	16.704	Gain
AGC_PKC_PKCa_PRKCA_ST	O95243	MBD4	P17252	PRKCA	S253	K247T	247	Missense	distal	-6	no	16.828	16.636	EPSD	ICGC;COSMIC	16.704	Loss
AGC_PKC_PKCa_PRKCA_ST	O95243	MBD4	P17252	PRKCA	S262	S262R	262	Missense	central	0	yes	19.022	0.000	PhosphoSitePlus;EPSD	ICGC	16.704	Loss
AGC_PKC_PKCa_PRKCA_ST	O95243	MBD4	P17252	PRKCA	S262	S266Y	266	Missense	distal	4	no	19.022	18.624	PhosphoSitePlus;EPSD	ICGC;COSMIC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	O95243	MBD4	P17252	PRKCA	S266	A273T	273	Missense	distal	7	no	19.954	19.963	EPSD	ICGC;COSMIC	16.704	Up-regulation
AGC_PKC_PKCa_PRKCA_ST	O95243	MBD4	P17252	PRKCA	S266	S262R	262	Missense	distal	-4	no	19.954	20.148	EPSD	ICGC	16.704	Up-regulation
AGC_PKC_PKCa_PRKCA_ST	O95243	MBD4	P17252	PRKCA	S266	S266Y	266	Missense	central	0	yes	19.954	0.000	EPSD	ICGC;COSMIC	16.704	Loss
AGC_PKC_PKCa_PRKCA_ST	O95243	MBD4	P17252	PRKCA	S318	S316L	316	Missense	proximal	-2	no	16.102	16.715	EPSD	ICGC	16.704	Gain
AGC_PKC_PKCa_PRKCA_ST	O95243	MBD4	P17252	PRKCA	S380	E381K	381	Missense	proximal	1	no	15.353	16.957	EPSD	ICGC;COSMIC	16.704	Gain
AGC_PKC_PKCa_PRKCA_ST	P48048	KCNJ1	P17252	PRKCA	S4	R6W	6	Missense	proximal	2	no	17.686	12.246	EPSD;PhosphoSitePlus	ICGC;GDSC	16.704	Loss
AGC_PKC_PKCa_PRKCA_ST	P48048	KCNJ1	P17252	PRKCA	S4	R6Q	6	Missense	proximal	2	no	17.686	13.851	EPSD;PhosphoSitePlus	ICGC	16.704	Loss
AGC_PKC_PKCa_PRKCA_ST	P48048	KCNJ1	P17252	PRKCA	S4	D10E	10	Missense	distal	6	no	17.686	17.669	EPSD;PhosphoSitePlus	ICGC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	P48048	KCNJ1	P17252	PRKCA	S201	G204D	204	Missense	distal	3	no	18.433	17.348	PhosphoSitePlus;EPSD	ICGC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	P55042	RRAD	P17252	PRKCA	S39	R45L	45	Missense	distal	6	no	17.384	17.301	EPSD	ICGC;COSMIC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	P55042	RRAD	P17252	PRKCA	S257	R254C	254	Missense	distal	-3	no	19.878	17.138	PhosphoSitePlus;EPSD	ICGC;COSMIC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	P55042	RRAD	P17252	PRKCA	S257	R264W	264	Missense	distal	7	no	19.878	19.697	PhosphoSitePlus;EPSD	ICGC;COSMIC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	P55042	RRAD	P17252	PRKCA	S273	R280C	280	Missense	distal	7	no	20.547	20.323	EPSD;PhosphoSitePlus	ICGC;COSMIC;GDSC;CCLE	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	P55042	RRAD	P17252	PRKCA	S273	A278V	278	Missense	distal	5	no	20.547	20.163	EPSD;PhosphoSitePlus	ICGC;COSMIC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	P55042	RRAD	P17252	PRKCA	S290	A297T	297	Missense	distal	7	no	18.882	18.891	EPSD;PhosphoSitePlus	ICGC;COSMIC	16.704	Up-regulation
AGC_PKC_PKCa_PRKCA_ST	P55042	RRAD	P17252	PRKCA	S290	R291H	291	Missense	proximal	1	no	18.882	18.069	EPSD;PhosphoSitePlus	ICGC;COSMIC;GDSC;CCLE	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	P55042	RRAD	P17252	PRKCA	S290	R284S	284	Missense	distal	-6	no	18.882	18.809	EPSD;PhosphoSitePlus	ICGC;COSMIC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	P11831	SRF	P17252	PRKCA	S16	G19W	19	Missense	distal	3	no	21.197	18.903	EPSD	ICGC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	P11831	SRF	P17252	PRKCA	S16	G15V	15	Missense	proximal	-1	no	21.197	19.487	EPSD	ICGC;COSMIC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	P11831	SRF	P17252	PRKCA	S101	G108C	108	Missense	distal	7	no	17.000	16.801	EPSD	ICGC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	P11831	SRF	P17252	PRKCA	S101	G97A	97	Missense	distal	-4	no	17.000	16.996	EPSD	ICGC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	P11831	SRF	P17252	PRKCA	S101	E104D	104	Missense	distal	3	no	17.000	16.514	EPSD	ICGC;COSMIC	16.704	Loss
AGC_PKC_PKCa_PRKCA_ST	P11831	SRF	P17252	PRKCA	S103	G108C	108	Missense	distal	5	no	17.008	16.557	EPSD	ICGC	16.704	Loss
AGC_PKC_PKCa_PRKCA_ST	P11831	SRF	P17252	PRKCA	S103	G97A	97	Missense	distal	-6	no	17.008	17.005	EPSD	ICGC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	P11831	SRF	P17252	PRKCA	S103	E104D	104	Missense	proximal	1	no	17.008	16.975	EPSD	ICGC;COSMIC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	P11831	SRF	P17252	PRKCA	S237	A238S	238	Missense	proximal	1	no	18.458	17.660	EPSD	ICGC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	P04004	VTN	P17252	PRKCA	S171	F173L	173	Missense	proximal	2	no	16.706	16.022	EPSD	ICGC;COSMIC	16.704	Loss
AGC_PKC_PKCa_PRKCA_ST	P04004	VTN	P17252	PRKCA	S171	S171F	171	Missense	central	0	yes	16.706	0.000	EPSD	ICGC	16.704	Loss
AGC_PKC_PKCa_PRKCA_ST	P04004	VTN	P17252	PRKCA	S171	L172I	172	Missense	proximal	1	no	16.706	17.543	EPSD	ICGC;COSMIC	16.704	Up-regulation
AGC_PKC_PKCa_PRKCA_ST	P04004	VTN	P17252	PRKCA	S225	L221V	221	Missense	distal	-4	no	17.604	17.563	EPSD	ICGC;COSMIC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	P04004	VTN	P17252	PRKCA	S364	R362H	362	Missense	proximal	-2	no	18.324	13.770	EPSD	ICGC;COSMIC;CCLE	16.704	Loss
AGC_PKC_PKCa_PRKCA_ST	P04004	VTN	P17252	PRKCA	S364	A366T	366	Missense	proximal	2	no	18.324	18.212	EPSD	ICGC;COSMIC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	P04004	VTN	P17252	PRKCA	S364	K368Q	368	Missense	distal	4	no	18.324	17.935	EPSD	ICGC;COSMIC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	P04004	VTN	P17252	PRKCA	S364	R370K	370	Missense	distal	6	no	18.324	18.311	EPSD	ICGC;COSMIC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	P04004	VTN	P17252	PRKCA	S381	R374H	374	Missense	distal	-7	no	21.671	21.664	EPSD;PhosphoSitePlus	ICGC;COSMIC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	P04004	VTN	P17252	PRKCA	S381	R376H	376	Missense	distal	-5	no	21.671	21.316	EPSD;PhosphoSitePlus	ICGC;COSMIC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	P04004	VTN	P17252	PRKCA	S381	R383Q	383	Missense	proximal	2	no	21.671	17.837	EPSD;PhosphoSitePlus	ICGC;COSMIC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	P04004	VTN	P17252	PRKCA	S386	R389S	389	Missense	distal	3	no	18.744	17.352	EPSD;PhosphoSitePlus	ICGC;COSMIC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	P04004	VTN	P17252	PRKCA	S386	R389H	389	Missense	distal	3	no	18.744	18.031	EPSD;PhosphoSitePlus	ICGC;COSMIC;GDSC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	P04004	VTN	P17252	PRKCA	S386	Q391K	391	Missense	distal	5	no	18.744	18.896	EPSD;PhosphoSitePlus	ICGC;COSMIC	16.704	Up-regulation
AGC_PKC_PKCa_PRKCA_ST	P04004	VTN	P17252	PRKCA	S386	R383Q	383	Missense	distal	-3	no	18.744	15.886	EPSD;PhosphoSitePlus	ICGC;COSMIC	16.704	Loss
AGC_PKC_PKCa_PRKCA_ST	P04004	VTN	P17252	PRKCA	S393	R389S	389	Missense	distal	-4	no	19.847	19.654	PhosphoSitePlus;EPSD	ICGC;COSMIC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	P04004	VTN	P17252	PRKCA	S393	A399T	399	Missense	distal	6	no	19.847	19.769	PhosphoSitePlus;EPSD	ICGC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	P04004	VTN	P17252	PRKCA	S393	R389H	389	Missense	distal	-4	no	19.847	19.273	PhosphoSitePlus;EPSD	ICGC;COSMIC;GDSC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	P04004	VTN	P17252	PRKCA	S393	Q391K	391	Missense	proximal	-2	no	19.847	19.979	PhosphoSitePlus;EPSD	ICGC;COSMIC	16.704	Up-regulation
AGC_PKC_PKCa_PRKCA_ST	P04004	VTN	P17252	PRKCA	S393	R398H	398	Missense	distal	5	no	19.847	19.588	PhosphoSitePlus;EPSD	ICGC;COSMIC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	P04004	VTN	P17252	PRKCA	S397	A399T	399	Missense	proximal	2	no	18.183	18.071	EPSD;PhosphoSitePlus	ICGC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	P04004	VTN	P17252	PRKCA	S397	Q391K	391	Missense	distal	-6	no	18.183	18.319	EPSD;PhosphoSitePlus	ICGC;COSMIC	16.704	Up-regulation
AGC_PKC_PKCa_PRKCA_ST	P04004	VTN	P17252	PRKCA	S397	R398H	398	Missense	proximal	1	no	18.183	17.369	EPSD;PhosphoSitePlus	ICGC;COSMIC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	P23528	CFL1	P17252	PRKCA	S94	K95N	95	Missense	proximal	1	no	16.730	15.565	EPSD	ICGC;COSMIC	16.704	Loss
AGC_PKC_PKCa_PRKCA_ST	Q96KS0	EGLN2	P17252	PRKCA	S132	D127G	127	Missense	distal	-5	no	16.684	16.779	EPSD;PhosphoSitePlus	ICGC;COSMIC	16.704	Gain
AGC_PKC_PKCa_PRKCA_ST	Q96KS0	EGLN2	P17252	PRKCA	S132	P129S	129	Missense	distal	-3	no	16.684	17.663	EPSD;PhosphoSitePlus	ICGC	16.704	Gain
AGC_PKC_PKCa_PRKCA_ST	Q96KS0	EGLN2	P17252	PRKCA	S226	R233H	233	Missense	distal	7	no	19.176	19.105	PhosphoSitePlus;EPSD	ICGC;COSMIC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	Q96KS0	EGLN2	P17252	PRKCA	S226	R220L	220	Missense	distal	-6	no	19.176	19.038	PhosphoSitePlus;EPSD	ICGC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	Q96KS0	EGLN2	P17252	PRKCA	S234	R236L	236	Missense	proximal	2	no	20.437	15.450	EPSD;PhosphoSitePlus	ICGC;COSMIC	16.704	Loss
AGC_PKC_PKCa_PRKCA_ST	Q96KS0	EGLN2	P17252	PRKCA	S234	R233H	233	Missense	proximal	-1	no	20.437	20.114	EPSD;PhosphoSitePlus	ICGC;COSMIC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	Q07869	PPARA	P17252	PRKCA	S179	E180D	180	Missense	proximal	1	no	19.047	19.015	EPSD;PhosphoSitePlus	ICGC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	Q07869	PPARA	P17252	PRKCA	S230	V227A	227	Missense	distal	-3	no	17.877	17.118	PhosphoSitePlus;EPSD	ICGC;COSMIC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	Q07869	PPARA	P17252	PRKCA	S230	P237Q	237	Missense	distal	7	no	17.877	17.883	PhosphoSitePlus;EPSD	ICGC;COSMIC	16.704	Up-regulation
AGC_PKC_PKCa_PRKCA_ST	P15311	EZR	P17252	PRKCA	S66	V65G	65	Missense	proximal	-1	no	15.197	16.908	EPSD	ICGC;COSMIC	16.704	Gain
AGC_PKC_PKCa_PRKCA_ST	P15311	EZR	P17252	PRKCA	S249	D252H	252	Missense	distal	3	no	16.474	17.487	EPSD	ICGC	16.704	Gain
AGC_PKC_PKCa_PRKCA_ST	P15311	EZR	P17252	PRKCA	T332	E334K	334	Missense	proximal	2	no	18.765	24.045	EPSD	ICGC;COSMIC	16.704	Up-regulation
AGC_PKC_PKCa_PRKCA_ST	P15311	EZR	P17252	PRKCA	S366	Q368K	368	Missense	proximal	2	no	14.032	17.445	EPSD	ICGC;COSMIC	16.704	Gain
AGC_PKC_PKCa_PRKCA_ST	P04637	TP53	P17252	PRKCA	S9	E11K	11	Missense	proximal	2	no	15.572	20.851	EPSD	ICGC;COSMIC	16.704	Gain
AGC_PKC_PKCa_PRKCA_ST	P04637	TP53	P17252	PRKCA	S99	Q100K	100	Missense	proximal	1	no	17.589	17.744	EPSD	ICGC;COSMIC	16.704	Up-regulation
AGC_PKC_PKCa_PRKCA_ST	P04637	TP53	P17252	PRKCA	S99	P92T	92	Missense	distal	-7	no	17.589	17.590	EPSD	ICGC;COSMIC	16.704	Up-regulation
AGC_PKC_PKCa_PRKCA_ST	P04637	TP53	P17252	PRKCA	S99	P92H	92	Missense	distal	-7	no	17.589	17.591	EPSD	ICGC;COSMIC	16.704	Up-regulation
AGC_PKC_PKCa_PRKCA_ST	P04637	TP53	P17252	PRKCA	S99	G105A	105	Missense	distal	6	no	17.589	17.697	EPSD	ICGC;COSMIC	16.704	Up-regulation
AGC_PKC_PKCa_PRKCA_ST	P04637	TP53	P17252	PRKCA	T211	H214D	214	Missense	distal	3	no	18.834	17.821	EPSD	ICGC;COSMIC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	P04637	TP53	P17252	PRKCA	T211	H214Y	214	Missense	distal	3	no	18.834	17.278	EPSD	ICGC;COSMIC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	P04637	TP53	P17252	PRKCA	T211	T211P	211	Missense	central	0	yes	18.834	0.000	EPSD	ICGC;COSMIC	16.704	Loss
AGC_PKC_PKCa_PRKCA_ST	P04637	TP53	P17252	PRKCA	T211	F212V	212	Missense	proximal	1	no	18.834	18.301	EPSD	ICGC;COSMIC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	P04637	TP53	P17252	PRKCA	T211	D208V	208	Missense	distal	-3	no	18.834	20.186	EPSD	ICGC;COSMIC	16.704	Up-regulation
AGC_PKC_PKCa_PRKCA_ST	P04637	TP53	P17252	PRKCA	T211	V217G	217	Missense	distal	6	no	18.834	18.845	EPSD	ICGC;COSMIC;CCLE	16.704	Up-regulation
AGC_PKC_PKCa_PRKCA_ST	P04637	TP53	P17252	PRKCA	T211	S215T	215	Missense	distal	4	no	18.834	18.403	EPSD	ICGC;COSMIC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	P04637	TP53	P17252	PRKCA	S215	T211P	211	Missense	distal	-4	no	16.529	17.019	EPSD	ICGC;COSMIC	16.704	Gain
AGC_PKC_PKCa_PRKCA_ST	P04637	TP53	P17252	PRKCA	S269	A276V	276	Missense	distal	7	no	17.682	17.627	EPSD	ICGC;COSMIC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	P04637	TP53	P17252	PRKCA	S269	V274A	274	Missense	distal	5	no	17.682	18.066	EPSD	ICGC;COSMIC	16.704	Up-regulation
AGC_PKC_PKCa_PRKCA_ST	P04637	TP53	P17252	PRKCA	S269	V272E	272	Missense	distal	3	no	17.682	18.298	EPSD	ICGC;COSMIC;CCLE	16.704	Up-regulation
AGC_PKC_PKCa_PRKCA_ST	P04637	TP53	P17252	PRKCA	S269	L265T	265	Missense	distal	-4	no	17.682	17.451	EPSD	ICGC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	P04637	TP53	P17252	PRKCA	S269	N268I	268	Missense	proximal	-1	no	17.682	16.556	EPSD	ICGC;COSMIC;GDSC;CCLE	16.704	Loss
AGC_PKC_PKCa_PRKCA_ST	P04637	TP53	P17252	PRKCA	S269	E271D	271	Missense	proximal	2	no	17.682	18.104	EPSD	ICGC;COSMIC	16.704	Up-regulation
AGC_PKC_PKCa_PRKCA_ST	P04637	TP53	P17252	PRKCA	T304	H297Q	297	Missense	distal	-7	no	16.706	16.705	EPSD	ICGC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	P04637	TP53	P17252	PRKCA	T304	P301T	301	Missense	distal	-3	no	16.706	16.391	EPSD	ICGC;COSMIC	16.704	Loss
AGC_PKC_PKCa_PRKCA_ST	P04637	TP53	P17252	PRKCA	S371	T377P	377	Missense	distal	6	no	18.173	18.255	EPSD;PhosphoSitePlus	ICGC;COSMIC	16.704	Up-regulation
AGC_PKC_PKCa_PRKCA_ST	P04637	TP53	P17252	PRKCA	S371	G374C	374	Missense	distal	3	no	18.173	16.194	EPSD;PhosphoSitePlus	ICGC;COSMIC	16.704	Loss
AGC_PKC_PKCa_PRKCA_ST	P04637	TP53	P17252	PRKCA	T377	T377P	377	Missense	central	0	yes	17.083	0.000	PhosphoSitePlus;EPSD	ICGC;COSMIC	16.704	Loss
AGC_PKC_PKCa_PRKCA_ST	P04637	TP53	P17252	PRKCA	T377	G374C	374	Missense	distal	-3	no	17.083	17.605	PhosphoSitePlus;EPSD	ICGC;COSMIC	16.704	Up-regulation
AGC_PKC_PKCa_PRKCA_ST	P04637	TP53	P17252	PRKCA	T377	R379S	379	Missense	proximal	2	no	17.083	12.463	PhosphoSitePlus;EPSD	ICGC	16.704	Loss
AGC_PKC_PKCa_PRKCA_ST	P04637	TP53	P17252	PRKCA	T377	R379C	379	Missense	proximal	2	no	17.083	12.733	PhosphoSitePlus;EPSD	ICGC;COSMIC	16.704	Loss
AGC_PKC_PKCa_PRKCA_ST	P60983	GMFB	P17252	PRKCA	T27	R24L	24	Missense	distal	-3	no	16.999	12.644	EPSD	ICGC	16.704	Loss
AGC_PKC_PKCa_PRKCA_ST	P60983	GMFB	P17252	PRKCA	T27	R22H	22	Missense	distal	-5	no	16.999	16.644	EPSD	ICGC;COSMIC	16.704	Loss
AGC_PKC_PKCa_PRKCA_ST	P60880	SNAP25	P17252	PRKCA	S28	R30L	30	Missense	proximal	2	no	21.165	16.179	EPSD	ICGC	16.704	Loss
AGC_PKC_PKCa_PRKCA_ST	P60880	SNAP25	P17252	PRKCA	S28	R31C	31	Missense	distal	3	no	21.165	18.547	EPSD	ICGC;COSMIC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	P60880	SNAP25	P17252	PRKCA	T138	R135C	135	Missense	distal	-3	no	16.985	14.245	EPSD;PhosphoSitePlus	ICGC	16.704	Loss
AGC_PKC_PKCa_PRKCA_ST	P60880	SNAP25	P17252	PRKCA	T138	R135S	135	Missense	distal	-3	no	16.985	14.115	EPSD;PhosphoSitePlus	ICGC;COSMIC	16.704	Loss
AGC_PKC_PKCa_PRKCA_ST	Q8NF50	DOCK8	P17252	PRKCA	S6	S6N	6	Missense	central	0	yes	17.409	0.000	EPSD	ICGC	16.704	Loss
AGC_PKC_PKCa_PRKCA_ST	Q8NF50	DOCK8	P17252	PRKCA	S6	L4M	4	Missense	proximal	-2	no	17.409	18.116	EPSD	ICGC;COSMIC	16.704	Up-regulation
AGC_PKC_PKCa_PRKCA_ST	Q8NF50	DOCK8	P17252	PRKCA	S6	F12L	12	Missense	distal	6	no	17.409	17.440	EPSD	ICGC;COSMIC	16.704	Up-regulation
AGC_PKC_PKCa_PRKCA_ST	Q8NF50	DOCK8	P17252	PRKCA	S902	M901T	901	Missense	proximal	-1	no	17.839	16.801	EPSD	ICGC;COSMIC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	Q8NF50	DOCK8	P17252	PRKCA	S936	R934Q	934	Missense	proximal	-2	no	17.978	16.219	EPSD	ICGC;COSMIC	16.704	Loss
AGC_PKC_PKCa_PRKCA_ST	Q8NF50	DOCK8	P17252	PRKCA	S956	A951V	951	Missense	distal	-5	no	21.610	21.526	EPSD	ICGC;COSMIC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	Q8NF50	DOCK8	P17252	PRKCA	S1080	Y1075H	1075	Missense	distal	-5	no	17.979	18.132	EPSD	ICGC	16.704	Up-regulation
AGC_PKC_PKCa_PRKCA_ST	Q8NF50	DOCK8	P17252	PRKCA	S1243	S1245R	1245	Missense	proximal	2	no	14.747	19.367	EPSD	ICGC;COSMIC	16.704	Gain
AGC_PKC_PKCa_PRKCA_ST	Q15311	RALBP1	P17252	PRKCA	S509	R516C	516	Missense	distal	7	no	16.726	16.503	EPSD;PhosphoSitePlus	ICGC;COSMIC	16.704	Loss
AGC_PKC_PKCa_PRKCA_ST	Q15311	RALBP1	P17252	PRKCA	S509	E510K	510	Missense	proximal	1	no	16.726	18.330	EPSD;PhosphoSitePlus	ICGC;COSMIC	16.704	Up-regulation
AGC_PKC_PKCa_PRKCA_ST	Q15311	RALBP1	P17252	PRKCA	S509	Q506H	506	Missense	distal	-3	no	16.726	15.727	EPSD;PhosphoSitePlus	ICGC;COSMIC	16.704	Loss
AGC_PKC_PKCa_PRKCA_ST	Q15311	RALBP1	P17252	PRKCA	S509	I507N	507	Missense	proximal	-2	no	16.726	17.118	EPSD;PhosphoSitePlus	ICGC;COSMIC	16.704	Up-regulation
AGC_PKC_PKCa_PRKCA_ST	Q12809	KCNH2	P17252	PRKCA	S250	S255L	255	Missense	distal	5	no	19.574	19.383	EPSD	ICGC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	Q12809	KCNH2	P17252	PRKCA	S283	D287N	287	Missense	distal	4	no	18.835	18.477	EPSD	ICGC;CCLE	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	Q12809	KCNH2	P17252	PRKCA	S283	D287H	287	Missense	distal	4	no	18.835	19.151	EPSD	ICGC	16.704	Up-regulation
AGC_PKC_PKCa_PRKCA_ST	Q12809	KCNH2	P17252	PRKCA	S284	D287N	287	Missense	distal	3	no	17.217	17.372	EPSD	ICGC;CCLE	16.704	Up-regulation
AGC_PKC_PKCa_PRKCA_ST	Q12809	KCNH2	P17252	PRKCA	S284	D287H	287	Missense	distal	3	no	17.217	18.230	EPSD	ICGC	16.704	Up-regulation
AGC_PKC_PKCa_PRKCA_ST	Q12809	KCNH2	P17252	PRKCA	S882	L877P	877	Missense	distal	-5	no	17.861	17.887	EPSD	ICGC	16.704	Up-regulation
AGC_PKC_PKCa_PRKCA_ST	Q99418	CYTH2	P17252	PRKCA	T276	R280H	280	Missense	distal	4	no	21.331	21.048	EPSD	ICGC;COSMIC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	Q99418	CYTH2	P17252	PRKCA	S392	R387T	387	Missense	distal	-5	no	22.263	22.164	PhosphoSitePlus	ICGC;COSMIC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	Q99418	CYTH2	P17252	PRKCA	S392	R390W	390	Missense	proximal	-2	no	22.263	20.265	PhosphoSitePlus	ICGC;COSMIC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	Q99418	CYTH2	P17252	PRKCA	S392	A386V	386	Missense	distal	-6	no	22.263	22.186	PhosphoSitePlus	ICGC;COSMIC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	P15336	ATF2	P17252	PRKCA	S340	S340L	340	Missense	central	0	yes	19.248	0.000	EPSD	ICGC;COSMIC	16.704	Loss
AGC_PKC_PKCa_PRKCA_ST	P15336	ATF2	P17252	PRKCA	S340	Q337H	337	Missense	distal	-3	no	19.248	18.250	EPSD	ICGC;COSMIC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	Q9NRY4	ARHGAP35	P17252	PRKCA	S46	H51Y	51	Missense	distal	5	no	17.404	17.549	EPSD	ICGC;COSMIC	16.704	Up-regulation
AGC_PKC_PKCa_PRKCA_ST	Q9NRY4	ARHGAP35	P17252	PRKCA	S46	C39R	39	Missense	distal	-7	no	17.404	17.423	EPSD	ICGC;COSMIC	16.704	Up-regulation
AGC_PKC_PKCa_PRKCA_ST	Q9NRY4	ARHGAP35	P17252	PRKCA	S46	E49K	49	Missense	distal	3	no	17.404	18.020	EPSD	ICGC;COSMIC	16.704	Up-regulation
AGC_PKC_PKCa_PRKCA_ST	Q9NRY4	ARHGAP35	P17252	PRKCA	S46	E49D	49	Missense	distal	3	no	17.404	16.917	EPSD	ICGC;COSMIC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	Q9NRY4	ARHGAP35	P17252	PRKCA	S46	D48Y	48	Missense	proximal	2	no	17.404	18.187	EPSD	ICGC;COSMIC	16.704	Up-regulation
AGC_PKC_PKCa_PRKCA_ST	Q9NRY4	ARHGAP35	P17252	PRKCA	S684	N691D	691	Missense	distal	7	no	18.850	18.876	EPSD	ICGC;COSMIC	16.704	Up-regulation
AGC_PKC_PKCa_PRKCA_ST	Q9NRY4	ARHGAP35	P17252	PRKCA	T685	N691D	691	Missense	distal	6	no	17.614	17.699	EPSD	ICGC;COSMIC	16.704	Up-regulation
AGC_PKC_PKCa_PRKCA_ST	Q9NRY4	ARHGAP35	P17252	PRKCA	S773	S773G	773	Missense	central	0	yes	17.378	0.000	EPSD	ICGC;COSMIC	16.704	Loss
AGC_PKC_PKCa_PRKCA_ST	Q9NRY4	ARHGAP35	P17252	PRKCA	S773	S769I	769	Missense	distal	-4	no	17.378	16.936	EPSD	ICGC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	Q9NRY4	ARHGAP35	P17252	PRKCA	S773	V780F	780	Missense	distal	7	no	17.378	17.371	EPSD	ICGC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	Q9NRY4	ARHGAP35	P17252	PRKCA	S845	V852F	852	Missense	distal	7	no	19.980	19.973	EPSD	ICGC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	Q9NRY4	ARHGAP35	P17252	PRKCA	S849	V852F	852	Missense	distal	3	no	17.000	16.950	EPSD	ICGC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	Q9NRY4	ARHGAP35	P17252	PRKCA	S1004	T1000A	1000	Missense	distal	-4	no	16.208	16.957	EPSD	ICGC;COSMIC	16.704	Gain
AGC_PKC_PKCa_PRKCA_ST	Q9NRY4	ARHGAP35	P17252	PRKCA	S1010	D1008Y	1008	Missense	proximal	-2	no	16.057	16.747	EPSD	ICGC	16.704	Gain
AGC_PKC_PKCa_PRKCA_ST	Q9NRY4	ARHGAP35	P17252	PRKCA	S1150	S1153I	1153	Missense	distal	3	no	19.515	18.357	EPSD	ICGC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	Q9NRY4	ARHGAP35	P17252	PRKCA	S1150	R1147C	1147	Missense	distal	-3	no	19.515	16.776	EPSD	ICGC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	Q9NRY4	ARHGAP35	P17252	PRKCA	S1170	R1167W	1167	Missense	distal	-3	no	20.359	18.006	EPSD	ICGC;COSMIC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	Q9NRY4	ARHGAP35	P17252	PRKCA	S1170	R1172W	1172	Missense	proximal	2	no	20.359	14.920	EPSD	ICGC;COSMIC;GDSC;CCLE	16.704	Loss
AGC_PKC_PKCa_PRKCA_ST	Q9NRY4	ARHGAP35	P17252	PRKCA	S1170	V1177M	1177	Missense	distal	7	no	20.359	20.427	EPSD	ICGC;COSMIC	16.704	Up-regulation
AGC_PKC_PKCa_PRKCA_ST	Q9NRY4	ARHGAP35	P17252	PRKCA	S1221	R1223S	1223	Missense	proximal	2	no	20.552	15.933	EPSD;PhosphoSitePlus	ICGC;COSMIC	16.704	Loss
AGC_PKC_PKCa_PRKCA_ST	Q9NRY4	ARHGAP35	P17252	PRKCA	S1221	R1216T	1216	Missense	distal	-5	no	20.552	20.453	EPSD;PhosphoSitePlus	ICGC;COSMIC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	Q9NRY4	ARHGAP35	P17252	PRKCA	T1226	R1223S	1223	Missense	distal	-3	no	22.224	19.355	EPSD;PhosphoSitePlus	ICGC;COSMIC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	Q9NRY4	ARHGAP35	P17252	PRKCA	S1236	W1242L	1242	Missense	distal	6	no	18.753	18.919	PhosphoSitePlus;EPSD	ICGC;COSMIC	16.704	Up-regulation
AGC_PKC_PKCa_PRKCA_ST	P16150	SPN	P17252	PRKCA	S291	V289M	289	Missense	proximal	-2	no	16.340	17.201	EPSD	ICGC;COSMIC	16.704	Gain
AGC_PKC_PKCa_PRKCA_ST	P16150	SPN	P17252	PRKCA	S336	R338H	338	Missense	proximal	2	no	19.202	14.178	EPSD	ICGC;COSMIC	16.704	Loss
AGC_PKC_PKCa_PRKCA_ST	P16150	SPN	P17252	PRKCA	S336	E334K	334	Missense	proximal	-2	no	19.202	21.701	EPSD	ICGC	16.704	Up-regulation
AGC_PKC_PKCa_PRKCA_ST	P16150	SPN	P17252	PRKCA	S336	R339W	339	Missense	distal	3	no	19.202	16.268	EPSD	ICGC	16.704	Loss
AGC_PKC_PKCa_PRKCA_ST	P16150	SPN	P17252	PRKCA	S336	D332N	332	Missense	distal	-4	no	19.202	19.550	EPSD	ICGC;COSMIC	16.704	Up-regulation
AGC_PKC_PKCa_PRKCA_ST	P16150	SPN	P17252	PRKCA	S337	R338H	338	Missense	proximal	1	no	17.483	16.670	EPSD	ICGC;COSMIC	16.704	Loss
AGC_PKC_PKCa_PRKCA_ST	P16150	SPN	P17252	PRKCA	S337	E334K	334	Missense	distal	-3	no	17.483	20.395	EPSD	ICGC	16.704	Up-regulation
AGC_PKC_PKCa_PRKCA_ST	P16150	SPN	P17252	PRKCA	S337	R339W	339	Missense	proximal	2	no	17.483	12.043	EPSD	ICGC	16.704	Loss
AGC_PKC_PKCa_PRKCA_ST	P16150	SPN	P17252	PRKCA	S337	D332N	332	Missense	distal	-5	no	17.483	17.512	EPSD	ICGC;COSMIC	16.704	Up-regulation
AGC_PKC_PKCa_PRKCA_ST	P16150	SPN	P17252	PRKCA	T341	R338H	338	Missense	distal	-3	no	17.830	13.974	EPSD	ICGC;COSMIC	16.704	Loss
AGC_PKC_PKCa_PRKCA_ST	P16150	SPN	P17252	PRKCA	T341	E334K	334	Missense	distal	-7	no	17.830	17.838	EPSD	ICGC	16.704	Up-regulation
AGC_PKC_PKCa_PRKCA_ST	P16150	SPN	P17252	PRKCA	T341	R339W	339	Missense	proximal	-2	no	17.830	15.833	EPSD	ICGC	16.704	Loss
AGC_PKC_PKCa_PRKCA_ST	P16150	SPN	P17252	PRKCA	S351	R352H	352	Missense	proximal	1	no	23.344	22.531	PhosphoSitePlus	ICGC;COSMIC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	P16150	SPN	P17252	PRKCA	S351	R352C	352	Missense	proximal	1	no	23.344	20.508	PhosphoSitePlus	ICGC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	P16150	SPN	P17252	PRKCA	S355	R352H	352	Missense	distal	-3	no	19.700	15.844	EPSD	ICGC;COSMIC	16.704	Loss
AGC_PKC_PKCa_PRKCA_ST	P16150	SPN	P17252	PRKCA	S355	R352C	352	Missense	distal	-3	no	19.700	16.961	EPSD	ICGC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	P16150	SPN	P17252	PRKCA	S368	P367H	367	Missense	proximal	-1	no	20.566	20.930	EPSD	ICGC;COSMIC	16.704	Up-regulation
AGC_PKC_PKCa_PRKCA_ST	O60716	CTNND1	P17252	PRKCA	T61	A56S	56	Missense	distal	-5	no	17.197	17.250	EPSD	ICGC;COSMIC;GDSC	16.704	Up-regulation
AGC_PKC_PKCa_PRKCA_ST	Q9NQA5	TRPV5	P17252	PRKCA	S155	R157H	157	Missense	proximal	2	no	22.736	17.713	EPSD	ICGC;COSMIC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	Q9NQA5	TRPV5	P17252	PRKCA	S155	R154H	154	Missense	proximal	-1	no	22.736	22.413	EPSD	ICGC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	Q9NQA5	TRPV5	P17252	PRKCA	S155	R153S	153	Missense	proximal	-2	no	22.736	19.435	EPSD	ICGC;COSMIC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	Q9NQA5	TRPV5	P17252	PRKCA	S299	S299F	299	Missense	central	0	yes	19.515	0.000	PhosphoSitePlus;EPSD	ICGC;COSMIC	16.704	Loss
AGC_PKC_PKCa_PRKCA_ST	Q9NQA5	TRPV5	P17252	PRKCA	S654	K652N	652	Missense	proximal	-2	no	19.496	17.927	EPSD;PhosphoSitePlus	ICGC;COSMIC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	Q9NQA5	TRPV5	P17252	PRKCA	S689	A692G	692	Missense	distal	3	no	15.778	16.736	EPSD	ICGC;COSMIC	16.704	Gain
AGC_PKC_PKCa_PRKCA_ST	Q9NQA5	TRPV5	P17252	PRKCA	S689	S687C	687	Missense	proximal	-2	no	15.778	17.380	EPSD	ICGC;COSMIC	16.704	Gain
AGC_PKC_PKCa_PRKCA_ST	P43629	KIR3DL1	P17252	PRKCA	S296	R298C	298	Missense	proximal	2	no	20.275	15.924	EPSD	ICGC;COSMIC;GDSC	16.704	Loss
AGC_PKC_PKCa_PRKCA_ST	P43629	KIR3DL1	P17252	PRKCA	S415	T412M	412	Missense	distal	-3	no	19.172	20.363	PhosphoSitePlus	ICGC;COSMIC	16.704	Up-regulation
AGC_PKC_PKCa_PRKCA_ST	P43629	KIR3DL1	P17252	PRKCA	S415	P418T	418	Missense	distal	3	no	19.172	18.867	PhosphoSitePlus	ICGC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	P43629	KIR3DL1	P17252	PRKCA	S415	P414T	414	Missense	proximal	-1	no	19.172	19.094	PhosphoSitePlus	ICGC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	P43629	KIR3DL1	P17252	PRKCA	S415	Q416L	416	Missense	proximal	1	no	19.172	18.942	PhosphoSitePlus	ICGC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	P43629	KIR3DL1	P17252	PRKCA	S415	R413L	413	Missense	proximal	-2	no	19.172	16.484	PhosphoSitePlus	ICGC;COSMIC	16.704	Loss
AGC_PKC_PKCa_PRKCA_ST	P43629	KIR3DL1	P17252	PRKCA	S415	P418L	418	Missense	distal	3	no	19.172	18.466	PhosphoSitePlus	ICGC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	O75955	FLOT1	P17252	PRKCA	S19	V13I	13	Missense	distal	-6	no	16.978	16.994	EPSD	ICGC;COSMIC	16.704	Up-regulation
AGC_PKC_PKCa_PRKCA_ST	O75955	FLOT1	P17252	PRKCA	T169	Q171R	171	Missense	proximal	2	no	15.399	19.233	EPSD	ICGC;COSMIC	16.704	Gain
AGC_PKC_PKCa_PRKCA_ST	P08833	IGFBP1	P17252	PRKCA	S83	C78R	78	Missense	distal	-5	no	20.287	20.962	EPSD	ICGC;COSMIC	16.704	Up-regulation
AGC_PKC_PKCa_PRKCA_ST	Q14315	FLNC	P17252	PRKCA	S78	V76M	76	Missense	proximal	-2	no	19.836	20.696	EPSD	ICGC;COSMIC	16.704	Up-regulation
AGC_PKC_PKCa_PRKCA_ST	Q14315	FLNC	P17252	PRKCA	S78	I71N	71	Missense	distal	-7	no	19.836	19.840	EPSD	ICGC;COSMIC	16.704	Up-regulation
AGC_PKC_PKCa_PRKCA_ST	Q14315	FLNC	P17252	PRKCA	S379	D374N	374	Missense	distal	-5	no	20.058	20.088	EPSD	ICGC	16.704	Up-regulation
AGC_PKC_PKCa_PRKCA_ST	Q14315	FLNC	P17252	PRKCA	S379	R381S	381	Missense	proximal	2	no	20.058	15.439	EPSD	ICGC;COSMIC	16.704	Loss
AGC_PKC_PKCa_PRKCA_ST	Q14315	FLNC	P17252	PRKCA	T423	G419V	419	Missense	distal	-4	no	17.935	17.371	EPSD	ICGC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	Q14315	FLNC	P17252	PRKCA	S480	P474L	474	Missense	distal	-6	no	22.448	22.415	EPSD	ICGC;COSMIC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	Q14315	FLNC	P17252	PRKCA	S480	K487N	487	Missense	distal	7	no	22.448	22.328	EPSD	ICGC;COSMIC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	Q14315	FLNC	P17252	PRKCA	S480	R478H	478	Missense	proximal	-2	no	22.448	17.895	EPSD	ICGC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	Q14315	FLNC	P17252	PRKCA	T909	E913G	913	Missense	distal	4	no	18.124	17.888	EPSD	ICGC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	Q14315	FLNC	P17252	PRKCA	T909	A907S	907	Missense	proximal	-2	no	18.124	17.907	EPSD	ICGC;COSMIC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	Q14315	FLNC	P17252	PRKCA	S1005	P1006S	1006	Missense	proximal	1	no	19.291	18.892	EPSD	ICGC;COSMIC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	Q14315	FLNC	P17252	PRKCA	S1005	R1002W	1002	Missense	distal	-3	no	19.291	16.937	EPSD	ICGC;COSMIC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	Q14315	FLNC	P17252	PRKCA	S1007	P1006S	1006	Missense	proximal	-1	no	18.149	18.449	EPSD	ICGC;COSMIC	16.704	Up-regulation
AGC_PKC_PKCa_PRKCA_ST	Q14315	FLNC	P17252	PRKCA	S1007	R1002W	1002	Missense	distal	-5	no	18.149	17.836	EPSD	ICGC;COSMIC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	Q14315	FLNC	P17252	PRKCA	T1809	G1807E	1807	Missense	proximal	-2	no	17.429	16.175	EPSD	ICGC	16.704	Loss
AGC_PKC_PKCa_PRKCA_ST	Q14315	FLNC	P17252	PRKCA	S2016	H2023R	2023	Missense	distal	7	no	18.009	18.081	EPSD	ICGC;COSMIC	16.704	Up-regulation
AGC_PKC_PKCa_PRKCA_ST	Q14315	FLNC	P17252	PRKCA	S2016	K2022N	2022	Missense	distal	6	no	18.009	17.848	EPSD	ICGC;COSMIC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	Q14315	FLNC	P17252	PRKCA	S2137	R2133L	2133	Missense	distal	-4	no	19.341	18.717	EPSD	ICGC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	Q14315	FLNC	P17252	PRKCA	S2137	E2136K	2136	Missense	proximal	-1	no	19.341	19.767	EPSD	ICGC	16.704	Up-regulation
AGC_PKC_PKCa_PRKCA_ST	Q14315	FLNC	P17252	PRKCA	T2139	E2136K	2136	Missense	distal	-3	no	16.045	18.957	EPSD	ICGC	16.704	Gain
AGC_PKC_PKCa_PRKCA_ST	Q14315	FLNC	P17252	PRKCA	S2233	R2228L	2228	Missense	distal	-5	no	17.184	17.057	EPSD	ICGC;COSMIC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	Q14315	FLNC	P17252	PRKCA	S2233	R2230C	2230	Missense	distal	-3	no	17.184	14.445	EPSD	ICGC	16.704	Loss
AGC_PKC_PKCa_PRKCA_ST	Q14315	FLNC	P17252	PRKCA	T2412	R2410Q	2410	Missense	proximal	-2	no	18.158	16.399	EPSD	ICGC;COSMIC	16.704	Loss
AGC_PKC_PKCa_PRKCA_ST	Q14315	FLNC	P17252	PRKCA	S2461	T2465I	2465	Missense	distal	4	no	16.929	15.915	EPSD	ICGC	16.704	Loss
AGC_PKC_PKCa_PRKCA_ST	Q14315	FLNC	P17252	PRKCA	S2461	R2467L	2467	Missense	distal	6	no	16.929	16.846	EPSD	ICGC;COSMIC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	P56537	EIF6	P17252	PRKCA	S6	N9K	9	Missense	distal	3	no	16.815	17.762	EPSD	ICGC	16.704	Up-regulation
AGC_PKC_PKCa_PRKCA_ST	Q06124	PTPN11	P17252	PRKCA	S34	A31S	31	Missense	distal	-3	no	16.192	17.770	EPSD	ICGC	16.704	Gain
AGC_PKC_PKCa_PRKCA_ST	Q06124	PTPN11	P17252	PRKCA	S140	P144H	144	Missense	distal	4	no	17.079	17.242	EPSD	ICGC;COSMIC	16.704	Up-regulation
AGC_PKC_PKCa_PRKCA_ST	Q06124	PTPN11	P17252	PRKCA	S140	E139D	139	Missense	proximal	-1	no	17.079	16.565	EPSD	ICGC;COSMIC	16.704	Loss
AGC_PKC_PKCa_PRKCA_ST	Q06124	PTPN11	P17252	PRKCA	S160	G158W	158	Missense	proximal	-2	no	16.701	17.576	EPSD	ICGC	16.704	Gain
AGC_PKC_PKCa_PRKCA_ST	Q06124	PTPN11	P17252	PRKCA	S264	R265Q	265	Missense	proximal	1	no	19.360	19.243	EPSD	ICGC;COSMIC;GDSC;CCLE	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	Q06124	PTPN11	P17252	PRKCA	S264	Q269E	269	Missense	distal	5	no	19.360	19.099	EPSD	ICGC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	Q14432	PDE3A	P17252	PRKCA	S292	V296L	296	Missense	distal	4	no	18.649	19.178	PhosphoSitePlus;EPSD	ICGC	16.704	Up-regulation
AGC_PKC_PKCa_PRKCA_ST	Q14432	PDE3A	P17252	PRKCA	S292	R291W	291	Missense	proximal	-1	no	18.649	17.064	PhosphoSitePlus;EPSD	ICGC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	Q14432	PDE3A	P17252	PRKCA	S293	V296L	296	Missense	distal	3	no	20.161	19.777	EPSD;PhosphoSitePlus	ICGC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	Q14432	PDE3A	P17252	PRKCA	S293	R291W	291	Missense	proximal	-2	no	20.161	18.164	EPSD;PhosphoSitePlus	ICGC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	Q14432	PDE3A	P17252	PRKCA	S294	V296L	296	Missense	proximal	2	no	17.739	17.766	EPSD	ICGC	16.704	Up-regulation
AGC_PKC_PKCa_PRKCA_ST	Q14432	PDE3A	P17252	PRKCA	S294	R291W	291	Missense	distal	-3	no	17.739	15.385	EPSD	ICGC	16.704	Loss
AGC_PKC_PKCa_PRKCA_ST	Q14432	PDE3A	P17252	PRKCA	S304	C303Y	303	Missense	proximal	-1	no	17.721	19.545	EPSD	ICGC;COSMIC	16.704	Up-regulation
AGC_PKC_PKCa_PRKCA_ST	Q14432	PDE3A	P17252	PRKCA	S305	S312P	312	Missense	distal	7	no	17.664	17.700	EPSD	ICGC	16.704	Up-regulation
AGC_PKC_PKCa_PRKCA_ST	Q14432	PDE3A	P17252	PRKCA	S305	C303Y	303	Missense	proximal	-2	no	17.664	16.636	EPSD	ICGC;COSMIC	16.704	Loss
AGC_PKC_PKCa_PRKCA_ST	Q14432	PDE3A	P17252	PRKCA	S463	R459W	459	Missense	distal	-4	no	16.813	15.987	EPSD	ICGC;COSMIC	16.704	Loss
AGC_PKC_PKCa_PRKCA_ST	Q14432	PDE3A	P17252	PRKCA	S463	R462H	462	Missense	proximal	-1	no	16.813	16.490	EPSD	ICGC;COSMIC	16.704	Loss
AGC_PKC_PKCa_PRKCA_ST	Q14432	PDE3A	P17252	PRKCA	S465	R459W	459	Missense	distal	-6	no	21.436	21.151	EPSD;PhosphoSitePlus	ICGC;COSMIC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	Q14432	PDE3A	P17252	PRKCA	S465	R462H	462	Missense	distal	-3	no	21.436	17.579	EPSD;PhosphoSitePlus	ICGC;COSMIC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	Q14432	PDE3A	P17252	PRKCA	S511	K509T	509	Missense	proximal	-2	no	18.953	17.686	EPSD	ICGC;COSMIC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	Q14432	PDE3A	P17252	PRKCA	S561	G560D	560	Missense	proximal	-1	no	17.658	16.915	EPSD	ICGC;COSMIC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	Q14432	PDE3A	P17252	PRKCA	S561	S558I	558	Missense	distal	-3	no	17.658	16.041	EPSD	ICGC	16.704	Loss
AGC_PKC_PKCa_PRKCA_ST	Q14432	PDE3A	P17252	PRKCA	S561	H562Q	562	Missense	proximal	1	no	17.658	18.354	EPSD	ICGC;COSMIC	16.704	Up-regulation
AGC_PKC_PKCa_PRKCA_ST	Q14432	PDE3A	P17252	PRKCA	S561	K556R	556	Missense	distal	-5	no	17.658	17.671	EPSD	ICGC;COSMIC	16.704	Up-regulation
AGC_PKC_PKCa_PRKCA_ST	Q14432	PDE3A	P17252	PRKCA	S593	S593F	593	Missense	central	0	yes	17.099	0.000	EPSD	ICGC	16.704	Loss
AGC_PKC_PKCa_PRKCA_ST	Q14432	PDE3A	P17252	PRKCA	S593	G595W	595	Missense	proximal	2	no	17.099	16.905	EPSD	ICGC;COSMIC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	Q14432	PDE3A	P17252	PRKCA	S654	L650P	650	Missense	distal	-4	no	19.438	19.698	EPSD	ICGC;COSMIC	16.704	Up-regulation
AGC_PKC_PKCa_PRKCA_ST	Q14432	PDE3A	P17252	PRKCA	S1060	K1064N	1064	Missense	distal	4	no	17.940	16.813	EPSD	ICGC;COSMIC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	Q8WZ42	TTN	P17252	PRKCA	S79	K81T	81	Missense	proximal	2	no	20.202	15.813	EPSD	ICGC;COSMIC	16.704	Loss
AGC_PKC_PKCa_PRKCA_ST	Q8WZ42	TTN	P17252	PRKCA	S79	S86F	86	Missense	distal	7	no	20.202	20.138	EPSD	ICGC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	Q8WZ42	TTN	P17252	PRKCA	S79	G85R	85	Missense	distal	6	no	20.202	20.351	EPSD	ICGC	16.704	Up-regulation
AGC_PKC_PKCa_PRKCA_ST	Q8WZ42	TTN	P17252	PRKCA	S79	A73D	73	Missense	distal	-6	no	20.202	20.154	EPSD	ICGC;COSMIC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	Q8WZ42	TTN	P17252	PRKCA	S112	R109L	109	Missense	distal	-3	no	17.735	13.380	EPSD	ICGC;COSMIC	16.704	Loss
AGC_PKC_PKCa_PRKCA_ST	Q8WZ42	TTN	P17252	PRKCA	S112	V115M	115	Missense	distal	3	no	17.735	18.321	EPSD	ICGC;COSMIC;GDSC;CCLE	16.704	Up-regulation
AGC_PKC_PKCa_PRKCA_ST	Q8WZ42	TTN	P17252	PRKCA	S282	I286K	286	Missense	distal	4	no	16.107	17.969	EPSD	ICGC	16.704	Gain
AGC_PKC_PKCa_PRKCA_ST	Q8WZ42	TTN	P17252	PRKCA	S284	I286K	286	Missense	proximal	2	no	14.361	18.972	EPSD	ICGC	16.704	Gain
AGC_PKC_PKCa_PRKCA_ST	Q8WZ42	TTN	P17252	PRKCA	S320	S320Y	320	Missense	central	0	yes	18.268	0.000	EPSD	ICGC;COSMIC	16.704	Loss
AGC_PKC_PKCa_PRKCA_ST	Q8WZ42	TTN	P17252	PRKCA	T330	R328C	328	Missense	proximal	-2	no	16.940	15.240	EPSD	ICGC;COSMIC	16.704	Loss
AGC_PKC_PKCa_PRKCA_ST	Q8WZ42	TTN	P17252	PRKCA	T330	T334I	334	Missense	distal	4	no	16.940	15.927	EPSD	ICGC	16.704	Loss
AGC_PKC_PKCa_PRKCA_ST	Q8WZ42	TTN	P17252	PRKCA	T363	T365K	365	Missense	proximal	2	no	14.036	18.425	EPSD	ICGC	16.704	Gain
AGC_PKC_PKCa_PRKCA_ST	Q8WZ42	TTN	P17252	PRKCA	T811	S813R	813	Missense	proximal	2	no	14.082	18.702	EPSD	ICGC	16.704	Gain
AGC_PKC_PKCa_PRKCA_ST	Q8WZ42	TTN	P17252	PRKCA	S813	T811I	811	Missense	proximal	-2	no	17.059	16.365	EPSD	ICGC;COSMIC	16.704	Loss
AGC_PKC_PKCa_PRKCA_ST	Q8WZ42	TTN	P17252	PRKCA	S813	R808H	808	Missense	distal	-5	no	17.059	16.704	EPSD	ICGC;COSMIC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	Q8WZ42	TTN	P17252	PRKCA	S813	A812D	812	Missense	proximal	-1	no	17.059	17.123	EPSD	ICGC	16.704	Up-regulation
AGC_PKC_PKCa_PRKCA_ST	Q8WZ42	TTN	P17252	PRKCA	S813	S813R	813	Missense	central	0	yes	17.059	0.000	EPSD	ICGC	16.704	Loss
AGC_PKC_PKCa_PRKCA_ST	Q8WZ42	TTN	P17252	PRKCA	S813	P809A	809	Missense	distal	-4	no	17.059	17.317	EPSD	ICGC;COSMIC	16.704	Up-regulation
AGC_PKC_PKCa_PRKCA_ST	Q8WZ42	TTN	P17252	PRKCA	S813	H815Y	815	Missense	proximal	2	no	17.059	17.587	EPSD	ICGC	16.704	Up-regulation
AGC_PKC_PKCa_PRKCA_ST	Q8WZ42	TTN	P17252	PRKCA	S813	H815D	815	Missense	proximal	2	no	17.059	16.804	EPSD	ICGC;COSMIC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	Q8WZ42	TTN	P17252	PRKCA	T863	T856S	856	Missense	distal	-7	no	17.979	17.981	EPSD	ICGC;COSMIC	16.704	Up-regulation
AGC_PKC_PKCa_PRKCA_ST	Q8WZ42	TTN	P17252	PRKCA	T863	E868D	868	Missense	distal	5	no	17.979	17.887	EPSD	ICGC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	Q8WZ42	TTN	P17252	PRKCA	S1118	P1121S	1121	Missense	distal	3	no	16.614	16.753	EPSD	ICGC	16.704	Gain
AGC_PKC_PKCa_PRKCA_ST	Q8WZ42	TTN	P17252	PRKCA	S1348	V1353A	1353	Missense	distal	5	no	20.626	21.010	EPSD	ICGC	16.704	Up-regulation
AGC_PKC_PKCa_PRKCA_ST	Q8WZ42	TTN	P17252	PRKCA	S1409	I1415M	1415	Missense	distal	6	no	16.932	16.965	EPSD	ICGC	16.704	Up-regulation
AGC_PKC_PKCa_PRKCA_ST	Q8WZ42	TTN	P17252	PRKCA	S1418	I1415M	1415	Missense	distal	-3	no	19.132	20.647	EPSD	ICGC	16.704	Up-regulation
AGC_PKC_PKCa_PRKCA_ST	Q8WZ42	TTN	P17252	PRKCA	S1418	P1424T	1424	Missense	distal	6	no	19.132	19.050	EPSD	ICGC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	Q8WZ42	TTN	P17252	PRKCA	S1418	R1421Q	1421	Missense	distal	3	no	19.132	16.678	EPSD	ICGC	16.704	Loss
AGC_PKC_PKCa_PRKCA_ST	Q8WZ42	TTN	P17252	PRKCA	S1423	P1424T	1424	Missense	proximal	1	no	17.149	17.076	EPSD	ICGC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	Q8WZ42	TTN	P17252	PRKCA	S1423	R1421Q	1421	Missense	proximal	-2	no	17.149	15.390	EPSD	ICGC	16.704	Loss
AGC_PKC_PKCa_PRKCA_ST	Q8WZ42	TTN	P17252	PRKCA	S1428	P1424T	1424	Missense	distal	-4	no	19.125	18.635	EPSD	ICGC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	Q8WZ42	TTN	P17252	PRKCA	S1428	R1421Q	1421	Missense	distal	-7	no	19.125	19.117	EPSD	ICGC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	Q8WZ42	TTN	P17252	PRKCA	S1428	S1433C	1433	Missense	distal	5	no	19.125	18.535	EPSD	ICGC;COSMIC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	Q8WZ42	TTN	P17252	PRKCA	S1433	S1433C	1433	Missense	central	0	yes	17.000	0.000	EPSD	ICGC;COSMIC	16.704	Loss
AGC_PKC_PKCa_PRKCA_ST	Q8WZ42	TTN	P17252	PRKCA	S1433	S1438P	1438	Missense	distal	5	no	17.000	17.159	EPSD	ICGC;COSMIC	16.704	Up-regulation
AGC_PKC_PKCa_PRKCA_ST	Q8WZ42	TTN	P17252	PRKCA	S1438	L1443P	1443	Missense	distal	5	no	16.537	16.887	EPSD	ICGC;COSMIC;GDSC	16.704	Gain
AGC_PKC_PKCa_PRKCA_ST	Q8WZ42	TTN	P17252	PRKCA	S2316	R2320C	2320	Missense	distal	4	no	18.161	16.760	EPSD	ICGC;COSMIC;GDSC;CCLE	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	Q8WZ42	TTN	P17252	PRKCA	S2316	T2313I	2313	Missense	distal	-3	no	18.161	17.837	EPSD	ICGC;COSMIC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	Q8WZ42	TTN	P17252	PRKCA	S2398	G2392C	2392	Missense	distal	-6	no	16.997	16.734	EPSD	ICGC;COSMIC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	Q8WZ42	TTN	P17252	PRKCA	S2398	V2395L	2395	Missense	distal	-3	no	16.997	16.331	EPSD	ICGC;COSMIC	16.704	Loss
AGC_PKC_PKCa_PRKCA_ST	Q8WZ42	TTN	P17252	PRKCA	S2398	R2400K	2400	Missense	proximal	2	no	16.997	16.575	EPSD	ICGC;COSMIC	16.704	Loss
AGC_PKC_PKCa_PRKCA_ST	Q8WZ42	TTN	P17252	PRKCA	S2437	S2437N	2437	Missense	central	0	yes	17.226	0.000	EPSD	ICGC;COSMIC	16.704	Loss
AGC_PKC_PKCa_PRKCA_ST	Q8WZ42	TTN	P17252	PRKCA	S2437	R2439C	2439	Missense	proximal	2	no	17.226	12.876	EPSD	ICGC;COSMIC	16.704	Loss
AGC_PKC_PKCa_PRKCA_ST	Q8WZ42	TTN	P17252	PRKCA	S2437	Y2443H	2443	Missense	distal	6	no	17.226	17.201	EPSD	ICGC;COSMIC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	Q8WZ42	TTN	P17252	PRKCA	S2437	L2434P	2434	Missense	distal	-3	no	17.226	17.733	EPSD	ICGC;COSMIC	16.704	Up-regulation
AGC_PKC_PKCa_PRKCA_ST	Q8WZ42	TTN	P17252	PRKCA	S2437	L2434F	2434	Missense	distal	-3	no	17.226	18.961	EPSD	ICGC	16.704	Up-regulation
AGC_PKC_PKCa_PRKCA_ST	Q8WZ42	TTN	P17252	PRKCA	S2763	R2765M	2765	Missense	proximal	2	no	17.684	13.236	EPSD	ICGC;COSMIC	16.704	Loss
AGC_PKC_PKCa_PRKCA_ST	Q8WZ42	TTN	P17252	PRKCA	S2763	I2761T	2761	Missense	proximal	-2	no	17.684	18.378	EPSD	ICGC;COSMIC	16.704	Up-regulation
AGC_PKC_PKCa_PRKCA_ST	Q8WZ42	TTN	P17252	PRKCA	S2763	S2756F	2756	Missense	distal	-7	no	17.684	17.676	EPSD	ICGC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	Q8WZ42	TTN	P17252	PRKCA	S3118	R3113H	3113	Missense	distal	-5	no	16.900	16.544	EPSD	ICGC	16.704	Loss
AGC_PKC_PKCa_PRKCA_ST	Q8WZ42	TTN	P17252	PRKCA	S3118	R3113C	3113	Missense	distal	-5	no	16.900	16.224	EPSD	ICGC;COSMIC	16.704	Loss
AGC_PKC_PKCa_PRKCA_ST	Q8WZ42	TTN	P17252	PRKCA	S3118	M3121L	3121	Missense	distal	3	no	16.900	15.930	EPSD	ICGC;COSMIC	16.704	Loss
AGC_PKC_PKCa_PRKCA_ST	Q8WZ42	TTN	P17252	PRKCA	S3118	S3118F	3118	Missense	central	0	yes	16.900	0.000	EPSD	ICGC;COSMIC	16.704	Loss
AGC_PKC_PKCa_PRKCA_ST	Q8WZ42	TTN	P17252	PRKCA	S3369	T3371K	3371	Missense	proximal	2	no	14.065	18.454	EPSD	ICGC	16.704	Gain
AGC_PKC_PKCa_PRKCA_ST	Q8WZ42	TTN	P17252	PRKCA	S3379	D3381Y	3381	Missense	proximal	2	no	16.371	17.154	EPSD	ICGC	16.704	Gain
AGC_PKC_PKCa_PRKCA_ST	Q8WZ42	TTN	P17252	PRKCA	S3776	E3778K	3778	Missense	proximal	2	no	13.490	18.770	EPSD	ICGC;COSMIC	16.704	Gain
AGC_PKC_PKCa_PRKCA_ST	Q8WZ42	TTN	P17252	PRKCA	S3918	E3915K	3915	Missense	distal	-3	no	16.207	19.119	EPSD	ICGC;COSMIC	16.704	Gain
AGC_PKC_PKCa_PRKCA_ST	Q8WZ42	TTN	P17252	PRKCA	S4010	A4016T	4016	Missense	distal	6	no	17.516	17.438	EPSD	ICGC;COSMIC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	Q8WZ42	TTN	P17252	PRKCA	S4010	P4014S	4014	Missense	distal	4	no	17.516	17.716	EPSD	ICGC	16.704	Up-regulation
AGC_PKC_PKCa_PRKCA_ST	Q8WZ42	TTN	P17252	PRKCA	S4010	R4012G	4012	Missense	proximal	2	no	17.516	12.271	EPSD	ICGC;COSMIC	16.704	Loss
AGC_PKC_PKCa_PRKCA_ST	Q8WZ42	TTN	P17252	PRKCA	S4010	S4010F	4010	Missense	central	0	yes	17.516	0.000	EPSD	ICGC;COSMIC	16.704	Loss
AGC_PKC_PKCa_PRKCA_ST	Q8WZ42	TTN	P17252	PRKCA	S4010	R4012K	4012	Missense	proximal	2	no	17.516	17.095	EPSD	ICGC;COSMIC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	Q8WZ42	TTN	P17252	PRKCA	S4010	E4007K	4007	Missense	distal	-3	no	17.516	20.428	EPSD	ICGC;COSMIC	16.704	Up-regulation
AGC_PKC_PKCa_PRKCA_ST	Q8WZ42	TTN	P17252	PRKCA	S4196	M4190I	4190	Missense	distal	-6	no	18.347	18.252	EPSD	ICGC;COSMIC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	Q8WZ42	TTN	P17252	PRKCA	S4196	S4192F	4192	Missense	distal	-4	no	18.347	18.288	EPSD	ICGC;COSMIC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	Q8WZ42	TTN	P17252	PRKCA	S4196	D4191N	4191	Missense	distal	-5	no	18.347	18.376	EPSD	ICGC;COSMIC;CCLE	16.704	Up-regulation
AGC_PKC_PKCa_PRKCA_ST	Q8WZ42	TTN	P17252	PRKCA	S4196	S4194L	4194	Missense	proximal	-2	no	18.347	18.960	EPSD	ICGC	16.704	Up-regulation
AGC_PKC_PKCa_PRKCA_ST	Q8WZ42	TTN	P17252	PRKCA	S4430	R4432Q	4432	Missense	proximal	2	no	17.744	13.909	EPSD	ICGC;COSMIC	16.704	Loss
AGC_PKC_PKCa_PRKCA_ST	Q8WZ42	TTN	P17252	PRKCA	S4430	C4429R	4429	Missense	proximal	-1	no	17.744	20.404	EPSD	ICGC;COSMIC	16.704	Up-regulation
AGC_PKC_PKCa_PRKCA_ST	Q8WZ42	TTN	P17252	PRKCA	S4430	Y4436C	4436	Missense	distal	6	no	17.744	17.557	EPSD	ICGC;COSMIC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	Q8WZ42	TTN	P17252	PRKCA	S4430	I4423M	4423	Missense	distal	-7	no	17.744	17.755	EPSD	ICGC;COSMIC	16.704	Up-regulation
AGC_PKC_PKCa_PRKCA_ST	Q8WZ42	TTN	P17252	PRKCA	S4430	I4437V	4437	Missense	distal	7	no	17.744	17.840	EPSD	ICGC;COSMIC	16.704	Up-regulation
AGC_PKC_PKCa_PRKCA_ST	Q8WZ42	TTN	P17252	PRKCA	S4430	D4427N	4427	Missense	distal	-3	no	17.744	18.559	EPSD	ICGC;COSMIC	16.704	Up-regulation
AGC_PKC_PKCa_PRKCA_ST	Q8WZ42	TTN	P17252	PRKCA	S4486	L4487I	4487	Missense	proximal	1	no	18.333	19.170	EPSD	ICGC	16.704	Up-regulation
AGC_PKC_PKCa_PRKCA_ST	Q8WZ42	TTN	P17252	PRKCA	S4486	K4485T	4485	Missense	proximal	-1	no	18.333	17.511	EPSD	ICGC;COSMIC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	Q8WZ42	TTN	P17252	PRKCA	S4486	T4489S	4489	Missense	distal	3	no	18.333	18.779	EPSD	ICGC;COSMIC	16.704	Up-regulation
AGC_PKC_PKCa_PRKCA_ST	Q8WZ42	TTN	P17252	PRKCA	S4486	T4488K	4488	Missense	proximal	2	no	18.333	22.722	EPSD	ICGC;COSMIC	16.704	Up-regulation
AGC_PKC_PKCa_PRKCA_ST	Q8WZ42	TTN	P17252	PRKCA	S4486	K4485N	4485	Missense	proximal	-1	no	18.333	17.731	EPSD	ICGC;COSMIC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	Q8WZ42	TTN	P17252	PRKCA	S4486	F4490V	4490	Missense	distal	4	no	18.333	17.373	EPSD	ICGC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	Q8WZ42	TTN	P17252	PRKCA	S4527	D4528N	4528	Missense	proximal	1	no	17.126	17.599	EPSD	ICGC;COSMIC	16.704	Up-regulation
AGC_PKC_PKCa_PRKCA_ST	Q8WZ42	TTN	P17252	PRKCA	S4527	R4525K	4525	Missense	proximal	-2	no	17.126	15.499	EPSD	ICGC;COSMIC	16.704	Loss
AGC_PKC_PKCa_PRKCA_ST	Q8WZ42	TTN	P17252	PRKCA	S4527	E4530D	4530	Missense	distal	3	no	17.126	16.640	EPSD	ICGC;COSMIC	16.704	Loss
AGC_PKC_PKCa_PRKCA_ST	Q8WZ42	TTN	P17252	PRKCA	S4527	P4522H	4522	Missense	distal	-5	no	17.126	16.872	EPSD	ICGC;COSMIC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	Q8WZ42	TTN	P17252	PRKCA	S4527	A4529E	4529	Missense	proximal	2	no	17.126	16.124	EPSD	ICGC;COSMIC	16.704	Loss
AGC_PKC_PKCa_PRKCA_ST	Q8WZ42	TTN	P17252	PRKCA	S4527	A4529V	4529	Missense	proximal	2	no	17.126	16.811	EPSD	ICGC;COSMIC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	Q8WZ42	TTN	P17252	PRKCA	S4527	S4521L	4521	Missense	distal	-6	no	17.126	17.061	EPSD	ICGC;COSMIC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	Q8WZ42	TTN	P17252	PRKCA	S4527	S4527F	4527	Missense	central	0	yes	17.126	0.000	EPSD	ICGC	16.704	Loss
AGC_PKC_PKCa_PRKCA_ST	Q8WZ42	TTN	P17252	PRKCA	S4527	W4524C	4524	Missense	distal	-3	no	17.126	16.741	EPSD	ICGC;COSMIC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	Q8WZ42	TTN	P17252	PRKCA	S4549	R4545T	4545	Missense	distal	-4	no	17.003	16.148	EPSD	ICGC;COSMIC	16.704	Loss
AGC_PKC_PKCa_PRKCA_ST	Q8WZ42	TTN	P17252	PRKCA	S4549	Q4543L	4543	Missense	distal	-6	no	17.003	17.007	EPSD	ICGC;COSMIC	16.704	Up-regulation
AGC_PKC_PKCa_PRKCA_ST	Q8WZ42	TTN	P17252	PRKCA	S4549	D4544Y	4544	Missense	distal	-5	no	17.003	16.879	EPSD	ICGC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	Q8WZ42	TTN	P17252	PRKCA	S4549	K4555R	4555	Missense	distal	6	no	17.003	17.015	EPSD	ICGC	16.704	Up-regulation
AGC_PKC_PKCa_PRKCA_ST	Q8WZ42	TTN	P17252	PRKCA	S4549	K4555T	4555	Missense	distal	6	no	17.003	16.895	EPSD	ICGC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	Q8WZ42	TTN	P17252	PRKCA	S4549	S4549P	4549	Missense	central	0	yes	17.003	0.000	EPSD	ICGC;COSMIC	16.704	Loss
AGC_PKC_PKCa_PRKCA_ST	Q8WZ42	TTN	P17252	PRKCA	S4549	S4549F	4549	Missense	central	0	yes	17.003	0.000	EPSD	ICGC;COSMIC	16.704	Loss
AGC_PKC_PKCa_PRKCA_ST	Q8WZ42	TTN	P17252	PRKCA	S4549	D4544N	4544	Missense	distal	-5	no	17.003	17.032	EPSD	ICGC	16.704	Up-regulation
AGC_PKC_PKCa_PRKCA_ST	Q8WZ42	TTN	P17252	PRKCA	S4549	A4552V	4552	Missense	distal	3	no	17.003	16.746	EPSD	ICGC;COSMIC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	Q8WZ42	TTN	P17252	PRKCA	S4549	R4545G	4545	Missense	distal	-4	no	17.003	16.901	EPSD	ICGC;COSMIC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	Q8WZ42	TTN	P17252	PRKCA	S4549	Y4548H	4548	Missense	proximal	-1	no	17.003	17.516	EPSD	ICGC;COSMIC	16.704	Up-regulation
AGC_PKC_PKCa_PRKCA_ST	Q8WZ42	TTN	P17252	PRKCA	S4553	D4559N	4559	Missense	distal	6	no	19.626	19.542	EPSD	ICGC;COSMIC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	Q8WZ42	TTN	P17252	PRKCA	S4553	K4555R	4555	Missense	proximal	2	no	19.626	20.048	EPSD	ICGC	16.704	Up-regulation
AGC_PKC_PKCa_PRKCA_ST	Q8WZ42	TTN	P17252	PRKCA	S4553	K4555T	4555	Missense	proximal	2	no	19.626	15.237	EPSD	ICGC	16.704	Loss
AGC_PKC_PKCa_PRKCA_ST	Q8WZ42	TTN	P17252	PRKCA	S4553	S4549P	4549	Missense	distal	-4	no	19.626	19.455	EPSD	ICGC;COSMIC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	Q8WZ42	TTN	P17252	PRKCA	S4553	S4549F	4549	Missense	distal	-4	no	19.626	19.568	EPSD	ICGC;COSMIC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	Q8WZ42	TTN	P17252	PRKCA	S4553	D4559H	4559	Missense	distal	6	no	19.626	19.638	EPSD	ICGC;COSMIC	16.704	Up-regulation
AGC_PKC_PKCa_PRKCA_ST	Q8WZ42	TTN	P17252	PRKCA	S4553	A4552V	4552	Missense	proximal	-1	no	19.626	18.723	EPSD	ICGC;COSMIC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	Q8WZ42	TTN	P17252	PRKCA	S4553	Y4548H	4548	Missense	distal	-5	no	19.626	19.780	EPSD	ICGC;COSMIC	16.704	Up-regulation
AGC_PKC_PKCa_PRKCA_ST	Q8WZ42	TTN	P17252	PRKCA	S4987	R4991Q	4991	Missense	distal	4	no	18.125	17.908	EPSD	ICGC;COSMIC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	Q8WZ42	TTN	P17252	PRKCA	S4987	A4986T	4986	Missense	proximal	-1	no	18.125	18.306	EPSD	ICGC;COSMIC	16.704	Up-regulation
AGC_PKC_PKCa_PRKCA_ST	Q8WZ42	TTN	P17252	PRKCA	S4987	S4993I	4993	Missense	distal	6	no	18.125	18.091	EPSD	ICGC;COSMIC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	Q8WZ42	TTN	P17252	PRKCA	S4987	A4986D	4986	Missense	proximal	-1	no	18.125	18.189	EPSD	ICGC;COSMIC	16.704	Up-regulation
AGC_PKC_PKCa_PRKCA_ST	Q8WZ42	TTN	P17252	PRKCA	S4987	V4985I	4985	Missense	proximal	-2	no	18.125	17.379	EPSD	ICGC;COSMIC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	Q8WZ42	TTN	P17252	PRKCA	S4987	G4981W	4981	Missense	distal	-6	no	18.125	17.948	EPSD	ICGC;COSMIC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	Q8WZ42	TTN	P17252	PRKCA	S4987	R4982I	4982	Missense	distal	-5	no	18.125	17.554	EPSD	ICGC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	Q8WZ42	TTN	P17252	PRKCA	S4987	S4993A	4993	Missense	distal	6	no	18.125	18.155	EPSD	ICGC	16.704	Up-regulation
AGC_PKC_PKCa_PRKCA_ST	Q8WZ42	TTN	P17252	PRKCA	S4987	S4993R	4993	Missense	distal	6	no	18.125	18.196	EPSD	ICGC	16.704	Up-regulation
AGC_PKC_PKCa_PRKCA_ST	Q8WZ42	TTN	P17252	PRKCA	S4993	R4991Q	4991	Missense	proximal	-2	no	21.337	19.578	EPSD	ICGC;COSMIC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	Q8WZ42	TTN	P17252	PRKCA	S4993	V4998I	4998	Missense	distal	5	no	21.337	21.424	EPSD	ICGC;COSMIC	16.704	Up-regulation
AGC_PKC_PKCa_PRKCA_ST	Q8WZ42	TTN	P17252	PRKCA	S4993	A4986T	4986	Missense	distal	-7	no	21.337	21.332	EPSD	ICGC;COSMIC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	Q8WZ42	TTN	P17252	PRKCA	S4993	N4996I	4996	Missense	distal	3	no	21.337	20.357	EPSD	ICGC;COSMIC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	Q8WZ42	TTN	P17252	PRKCA	S4993	S4993I	4993	Missense	central	0	yes	21.337	0.000	EPSD	ICGC;COSMIC	16.704	Loss
AGC_PKC_PKCa_PRKCA_ST	Q8WZ42	TTN	P17252	PRKCA	S4993	N4997S	4997	Missense	distal	4	no	21.337	22.047	EPSD	ICGC;COSMIC	16.704	Up-regulation
AGC_PKC_PKCa_PRKCA_ST	Q8WZ42	TTN	P17252	PRKCA	S4993	A4986D	4986	Missense	distal	-7	no	21.337	21.331	EPSD	ICGC;COSMIC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	Q8WZ42	TTN	P17252	PRKCA	S4993	N4996S	4996	Missense	distal	3	no	21.337	21.515	EPSD	ICGC	16.704	Up-regulation
AGC_PKC_PKCa_PRKCA_ST	Q8WZ42	TTN	P17252	PRKCA	S4993	S4993A	4993	Missense	central	0	yes	21.337	0.000	EPSD	ICGC	16.704	Loss
AGC_PKC_PKCa_PRKCA_ST	Q8WZ42	TTN	P17252	PRKCA	S4993	S4993R	4993	Missense	central	0	yes	21.337	0.000	EPSD	ICGC	16.704	Loss
AGC_PKC_PKCa_PRKCA_ST	Q8WZ42	TTN	P17252	PRKCA	S5072	G5077C	5077	Missense	distal	5	no	17.105	16.655	EPSD	ICGC;COSMIC	16.704	Loss
AGC_PKC_PKCa_PRKCA_ST	Q8WZ42	TTN	P17252	PRKCA	S5072	K5078I	5078	Missense	distal	6	no	17.105	17.012	EPSD	ICGC;COSMIC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	Q8WZ42	TTN	P17252	PRKCA	S5072	S5066F	5066	Missense	distal	-6	no	17.105	17.020	EPSD	ICGC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	Q8WZ42	TTN	P17252	PRKCA	S5072	W5073L	5073	Missense	proximal	1	no	17.105	17.481	EPSD	ICGC;COSMIC	16.704	Up-regulation
AGC_PKC_PKCa_PRKCA_ST	Q8WZ42	TTN	P17252	PRKCA	S5072	G5077D	5077	Missense	distal	5	no	17.105	17.025	EPSD	ICGC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	Q8WZ42	TTN	P17252	PRKCA	S5072	P5068S	5068	Missense	distal	-4	no	17.105	17.276	EPSD	ICGC;COSMIC	16.704	Up-regulation
AGC_PKC_PKCa_PRKCA_ST	Q8WZ42	TTN	P17252	PRKCA	S5072	E5079K	5079	Missense	distal	7	no	17.105	17.251	EPSD	ICGC;COSMIC	16.704	Up-regulation
AGC_PKC_PKCa_PRKCA_ST	Q8WZ42	TTN	P17252	PRKCA	S5072	G5065C	5065	Missense	distal	-7	no	17.105	17.095	EPSD	ICGC;COSMIC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	Q8WZ42	TTN	P17252	PRKCA	S5083	D5084G	5084	Missense	proximal	1	no	16.596	17.242	EPSD	ICGC;COSMIC	16.704	Gain
AGC_PKC_PKCa_PRKCA_ST	Q8WZ42	TTN	P17252	PRKCA	S5083	A5081T	5081	Missense	proximal	-2	no	16.596	16.788	EPSD	ICGC;COSMIC	16.704	Gain
AGC_PKC_PKCa_PRKCA_ST	Q8WZ42	TTN	P17252	PRKCA	S5083	E5079K	5079	Missense	distal	-4	no	16.596	17.327	EPSD	ICGC;COSMIC	16.704	Gain
AGC_PKC_PKCa_PRKCA_ST	Q8WZ42	TTN	P17252	PRKCA	S5123	G5125R	5125	Missense	proximal	2	no	13.774	19.019	EPSD	ICGC;COSMIC	16.704	Gain
AGC_PKC_PKCa_PRKCA_ST	Q8WZ42	TTN	P17252	PRKCA	T5155	Q5157R	5157	Missense	proximal	2	no	13.428	17.262	EPSD	ICGC;COSMIC	16.704	Gain
AGC_PKC_PKCa_PRKCA_ST	Q8WZ42	TTN	P17252	PRKCA	T5163	P5161L	5161	Missense	proximal	-2	no	16.350	16.705	EPSD	ICGC	16.704	Gain
AGC_PKC_PKCa_PRKCA_ST	Q8WZ42	TTN	P17252	PRKCA	S5270	N5263K	5263	Missense	distal	-7	no	18.889	18.894	EPSD	ICGC;COSMIC	16.704	Up-regulation
AGC_PKC_PKCa_PRKCA_ST	Q8WZ42	TTN	P17252	PRKCA	S5270	S5276Y	5276	Missense	distal	6	no	18.889	18.907	EPSD	ICGC;COSMIC	16.704	Up-regulation
AGC_PKC_PKCa_PRKCA_ST	Q8WZ42	TTN	P17252	PRKCA	S5270	R5265K	5265	Missense	distal	-5	no	18.889	18.876	EPSD	ICGC;COSMIC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	Q8WZ42	TTN	P17252	PRKCA	S5270	E5269K	5269	Missense	proximal	-1	no	18.889	19.315	EPSD	ICGC;COSMIC	16.704	Up-regulation
AGC_PKC_PKCa_PRKCA_ST	Q8WZ42	TTN	P17252	PRKCA	S5270	E5266K	5266	Missense	distal	-4	no	18.889	19.620	EPSD	ICGC;COSMIC	16.704	Up-regulation
AGC_PKC_PKCa_PRKCA_ST	Q8WZ42	TTN	P17252	PRKCA	S5270	R5274K	5274	Missense	distal	4	no	18.889	19.059	EPSD	ICGC;COSMIC	16.704	Up-regulation
AGC_PKC_PKCa_PRKCA_ST	Q8WZ42	TTN	P17252	PRKCA	S5271	E5269K	5269	Missense	proximal	-2	no	16.422	18.921	EPSD	ICGC;COSMIC	16.704	Gain
AGC_PKC_PKCa_PRKCA_ST	Q8WZ42	TTN	P17252	PRKCA	S5271	E5266K	5266	Missense	distal	-5	no	16.422	16.716	EPSD	ICGC;COSMIC	16.704	Gain
AGC_PKC_PKCa_PRKCA_ST	Q8WZ42	TTN	P17252	PRKCA	S5276	S5280C	5280	Missense	distal	4	no	20.337	19.182	EPSD	ICGC;COSMIC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	Q8WZ42	TTN	P17252	PRKCA	S5276	S5276Y	5276	Missense	central	0	yes	20.337	0.000	EPSD	ICGC;COSMIC	16.704	Loss
AGC_PKC_PKCa_PRKCA_ST	Q8WZ42	TTN	P17252	PRKCA	S5276	E5279A	5279	Missense	distal	3	no	20.337	19.977	EPSD	ICGC;COSMIC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	Q8WZ42	TTN	P17252	PRKCA	S5276	S5280Y	5280	Missense	distal	4	no	20.337	19.939	EPSD	ICGC;COSMIC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	Q8WZ42	TTN	P17252	PRKCA	S5276	E5269K	5269	Missense	distal	-7	no	20.337	20.345	EPSD	ICGC;COSMIC	16.704	Up-regulation
AGC_PKC_PKCa_PRKCA_ST	Q8WZ42	TTN	P17252	PRKCA	S5276	E5279G	5279	Missense	distal	3	no	20.337	20.935	EPSD	ICGC;COSMIC	16.704	Up-regulation
AGC_PKC_PKCa_PRKCA_ST	Q8WZ42	TTN	P17252	PRKCA	S5276	T5281N	5281	Missense	distal	5	no	20.337	20.291	EPSD	ICGC;COSMIC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	Q8WZ42	TTN	P17252	PRKCA	S5276	R5274K	5274	Missense	proximal	-2	no	20.337	18.709	EPSD	ICGC;COSMIC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	Q8WZ42	TTN	P17252	PRKCA	S5401	G5399C	5399	Missense	proximal	-2	no	16.332	17.504	EPSD	ICGC;COSMIC	16.704	Gain
AGC_PKC_PKCa_PRKCA_ST	Q8WZ42	TTN	P17252	PRKCA	S5404	G5399C	5399	Missense	distal	-5	no	18.159	17.773	EPSD	ICGC;COSMIC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	Q8WZ42	TTN	P17252	PRKCA	S5404	V5407M	5407	Missense	distal	3	no	18.159	18.745	EPSD	ICGC;COSMIC	16.704	Up-regulation
AGC_PKC_PKCa_PRKCA_ST	Q8WZ42	TTN	P17252	PRKCA	S5404	A5405D	5405	Missense	proximal	1	no	18.159	16.935	EPSD	ICGC;COSMIC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	Q8WZ42	TTN	P17252	PRKCA	S5404	S5401G	5401	Missense	distal	-3	no	18.159	17.767	EPSD	ICGC;COSMIC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	Q8WZ42	TTN	P17252	PRKCA	S5404	R5410G	5410	Missense	distal	6	no	18.159	18.009	EPSD	ICGC;COSMIC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	Q8WZ42	TTN	P17252	PRKCA	S5424	E5420D	5420	Missense	distal	-4	no	17.362	17.187	EPSD	ICGC;COSMIC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	Q8WZ42	TTN	P17252	PRKCA	S5424	G5427E	5427	Missense	distal	3	no	17.362	16.764	EPSD	ICGC;COSMIC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	Q8WZ42	TTN	P17252	PRKCA	S5424	G5428A	5428	Missense	distal	4	no	17.362	17.736	EPSD	ICGC;COSMIC	16.704	Up-regulation
AGC_PKC_PKCa_PRKCA_ST	Q8WZ42	TTN	P17252	PRKCA	S5424	R5426Q	5426	Missense	proximal	2	no	17.362	13.528	EPSD	ICGC;COSMIC	16.704	Loss
AGC_PKC_PKCa_PRKCA_ST	Q8WZ42	TTN	P17252	PRKCA	S5424	A5431S	5431	Missense	distal	7	no	17.362	17.364	EPSD	ICGC;COSMIC	16.704	Up-regulation
AGC_PKC_PKCa_PRKCA_ST	Q8WZ42	TTN	P17252	PRKCA	S5424	I5419N	5419	Missense	distal	-5	no	17.362	17.578	EPSD	ICGC;COSMIC	16.704	Up-regulation
AGC_PKC_PKCa_PRKCA_ST	Q8WZ42	TTN	P17252	PRKCA	S5424	T5422S	5422	Missense	proximal	-2	no	17.362	16.954	EPSD	ICGC;COSMIC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	Q8WZ42	TTN	P17252	PRKCA	S5424	S5424F	5424	Missense	central	0	yes	17.362	0.000	EPSD	ICGC	16.704	Loss
AGC_PKC_PKCa_PRKCA_ST	Q8WZ42	TTN	P17252	PRKCA	S5424	R5426W	5426	Missense	proximal	2	no	17.362	11.922	EPSD	ICGC;COSMIC	16.704	Loss
AGC_PKC_PKCa_PRKCA_ST	Q8WZ42	TTN	P17252	PRKCA	S5424	A5430T	5430	Missense	distal	6	no	17.362	17.284	EPSD	ICGC;COSMIC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	Q8WZ42	TTN	P17252	PRKCA	S5424	T5422I	5422	Missense	proximal	-2	no	17.362	16.668	EPSD	ICGC	16.704	Loss
AGC_PKC_PKCa_PRKCA_ST	Q8WZ42	TTN	P17252	PRKCA	S5501	Q5494E	5494	Missense	distal	-7	no	17.285	17.281	EPSD	ICGC;COSMIC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	Q8WZ42	TTN	P17252	PRKCA	S5501	A5506V	5506	Missense	distal	5	no	17.285	16.901	EPSD	ICGC;COSMIC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	Q8WZ42	TTN	P17252	PRKCA	S5501	S5501L	5501	Missense	central	0	yes	17.285	0.000	EPSD	ICGC;COSMIC	16.704	Loss
AGC_PKC_PKCa_PRKCA_ST	Q8WZ42	TTN	P17252	PRKCA	S5501	K5503E	5503	Missense	proximal	2	no	17.285	12.006	EPSD	ICGC;COSMIC	16.704	Loss
AGC_PKC_PKCa_PRKCA_ST	Q8WZ42	TTN	P17252	PRKCA	S5501	V5502L	5502	Missense	proximal	1	no	17.285	17.160	EPSD	ICGC;COSMIC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	Q8WZ42	TTN	P17252	PRKCA	S5501	A5498T	5498	Missense	distal	-3	no	17.285	17.571	EPSD	ICGC;COSMIC	16.704	Up-regulation
AGC_PKC_PKCa_PRKCA_ST	Q8WZ42	TTN	P17252	PRKCA	S5501	L5500I	5500	Missense	proximal	-1	no	17.285	16.421	EPSD	ICGC	16.704	Loss
AGC_PKC_PKCa_PRKCA_ST	Q8WZ42	TTN	P17252	PRKCA	S5573	E5575K	5575	Missense	proximal	2	no	12.879	18.159	EPSD	ICGC;COSMIC	16.704	Gain
AGC_PKC_PKCa_PRKCA_ST	Q8WZ42	TTN	P17252	PRKCA	S5588	K5590N	5590	Missense	proximal	2	no	18.546	13.597	EPSD	ICGC;COSMIC	16.704	Loss
AGC_PKC_PKCa_PRKCA_ST	Q8WZ42	TTN	P17252	PRKCA	S5588	S5587R	5587	Missense	proximal	-1	no	18.546	18.933	EPSD	ICGC;COSMIC	16.704	Up-regulation
AGC_PKC_PKCa_PRKCA_ST	Q8WZ42	TTN	P17252	PRKCA	S5588	D5583N	5583	Missense	distal	-5	no	18.546	18.575	EPSD	ICGC;COSMIC	16.704	Up-regulation
AGC_PKC_PKCa_PRKCA_ST	Q8WZ42	TTN	P17252	PRKCA	S5588	N5594I	5594	Missense	distal	6	no	18.546	18.614	EPSD	ICGC;COSMIC	16.704	Up-regulation
AGC_PKC_PKCa_PRKCA_ST	Q8WZ42	TTN	P17252	PRKCA	S5588	S5588R	5588	Missense	central	0	yes	18.546	0.000	EPSD	ICGC;COSMIC	16.704	Loss
AGC_PKC_PKCa_PRKCA_ST	Q8WZ42	TTN	P17252	PRKCA	S5588	V5584I	5584	Missense	distal	-4	no	18.546	18.576	EPSD	ICGC;COSMIC	16.704	Up-regulation
AGC_PKC_PKCa_PRKCA_ST	Q8WZ42	TTN	P17252	PRKCA	T5690	L5689M	5689	Missense	proximal	-1	no	16.130	17.209	EPSD	ICGC;COSMIC	16.704	Gain
AGC_PKC_PKCa_PRKCA_ST	Q8WZ42	TTN	P17252	PRKCA	S6124	S6129P	6129	Missense	distal	5	no	16.762	16.921	EPSD	ICGC;COSMIC	16.704	Up-regulation
AGC_PKC_PKCa_PRKCA_ST	Q8WZ42	TTN	P17252	PRKCA	S6124	S6117N	6117	Missense	distal	-7	no	16.762	16.757	EPSD	ICGC;COSMIC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	Q8WZ42	TTN	P17252	PRKCA	S6124	M6131I	6131	Missense	distal	7	no	16.762	16.598	EPSD	ICGC;COSMIC	16.704	Loss
AGC_PKC_PKCa_PRKCA_ST	Q8WZ42	TTN	P17252	PRKCA	S6124	R6126K	6126	Missense	proximal	2	no	16.762	16.341	EPSD	ICGC	16.704	Loss
AGC_PKC_PKCa_PRKCA_ST	Q8WZ42	TTN	P17252	PRKCA	S6124	S6117G	6117	Missense	distal	-7	no	16.762	16.758	EPSD	ICGC;COSMIC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	Q8WZ42	TTN	P17252	PRKCA	S6124	N6121S	6121	Missense	distal	-3	no	16.762	18.119	EPSD	ICGC	16.704	Up-regulation
AGC_PKC_PKCa_PRKCA_ST	Q8WZ42	TTN	P17252	PRKCA	S6680	S6686P	6686	Missense	distal	6	no	17.646	17.679	EPSD	ICGC	16.704	Up-regulation
AGC_PKC_PKCa_PRKCA_ST	Q8WZ42	TTN	P17252	PRKCA	S6680	S6680N	6680	Missense	central	0	yes	17.646	0.000	EPSD	ICGC	16.704	Loss
AGC_PKC_PKCa_PRKCA_ST	Q8WZ42	TTN	P17252	PRKCA	S6680	I6685V	6685	Missense	distal	5	no	17.646	17.558	EPSD	ICGC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	Q8WZ42	TTN	P17252	PRKCA	S6680	F6679V	6679	Missense	proximal	-1	no	17.646	16.891	EPSD	ICGC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	Q8WZ42	TTN	P17252	PRKCA	S6687	S6686P	6686	Missense	proximal	-1	no	17.125	16.826	EPSD	ICGC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	Q8WZ42	TTN	P17252	PRKCA	S6687	R6689S	6689	Missense	proximal	2	no	17.125	12.506	EPSD	ICGC;COSMIC	16.704	Loss
AGC_PKC_PKCa_PRKCA_ST	Q8WZ42	TTN	P17252	PRKCA	S6687	S6680N	6680	Missense	distal	-7	no	17.125	17.121	EPSD	ICGC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	Q8WZ42	TTN	P17252	PRKCA	S6687	I6685V	6685	Missense	proximal	-2	no	17.125	17.872	EPSD	ICGC	16.704	Up-regulation
AGC_PKC_PKCa_PRKCA_ST	Q8WZ42	TTN	P17252	PRKCA	S6687	R6689K	6689	Missense	proximal	2	no	17.125	16.704	EPSD	ICGC;COSMIC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	Q8WZ42	TTN	P17252	PRKCA	S7088	S7083T	7083	Missense	distal	-5	no	16.676	17.004	EPSD	ICGC;COSMIC	16.704	Gain
AGC_PKC_PKCa_PRKCA_ST	Q8WZ42	TTN	P17252	PRKCA	S7286	Q7284L	7284	Missense	proximal	-2	no	17.787	16.858	EPSD	ICGC;COSMIC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	Q8WZ42	TTN	P17252	PRKCA	S7286	P7290H	7290	Missense	distal	4	no	17.787	17.950	EPSD	ICGC;COSMIC	16.704	Up-regulation
AGC_PKC_PKCa_PRKCA_ST	Q8WZ42	TTN	P17252	PRKCA	S7330	L7332R	7332	Missense	proximal	2	no	16.585	21.572	EPSD	ICGC	16.704	Gain
AGC_PKC_PKCa_PRKCA_ST	Q8WZ42	TTN	P17252	PRKCA	S7330	H7333R	7333	Missense	distal	3	no	16.585	17.297	EPSD	ICGC;COSMIC	16.704	Gain
AGC_PKC_PKCa_PRKCA_ST	Q8WZ42	TTN	P17252	PRKCA	S7330	E7334K	7334	Missense	distal	4	no	16.585	17.124	EPSD	ICGC;COSMIC	16.704	Gain
AGC_PKC_PKCa_PRKCA_ST	Q8WZ42	TTN	P17252	PRKCA	S7330	D7329N	7329	Missense	proximal	-1	no	16.585	16.923	EPSD	ICGC	16.704	Gain
AGC_PKC_PKCa_PRKCA_ST	Q8WZ42	TTN	P17252	PRKCA	S7330	E7331K	7331	Missense	proximal	1	no	16.585	18.189	EPSD	ICGC;COSMIC	16.704	Gain
AGC_PKC_PKCa_PRKCA_ST	Q8WZ42	TTN	P17252	PRKCA	S7335	L7332R	7332	Missense	distal	-3	no	14.145	18.501	EPSD	ICGC	16.704	Gain
AGC_PKC_PKCa_PRKCA_ST	Q8WZ42	TTN	P17252	PRKCA	S7335	H7333R	7333	Missense	proximal	-2	no	14.145	18.699	EPSD	ICGC;COSMIC	16.704	Gain
AGC_PKC_PKCa_PRKCA_ST	Q8WZ42	TTN	P17252	PRKCA	T7388	P7385S	7385	Missense	distal	-3	no	15.838	16.817	EPSD	ICGC	16.704	Gain
AGC_PKC_PKCa_PRKCA_ST	Q8WZ42	TTN	P17252	PRKCA	S7471	C7468Y	7468	Missense	distal	-3	no	17.534	15.714	EPSD	ICGC;COSMIC	16.704	Loss
AGC_PKC_PKCa_PRKCA_ST	Q8WZ42	TTN	P17252	PRKCA	S7471	G7464E	7464	Missense	distal	-7	no	17.534	17.531	EPSD	ICGC;COSMIC;CCLE	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	Q8WZ42	TTN	P17252	PRKCA	S7471	T7467M	7467	Missense	distal	-4	no	17.534	18.468	EPSD	ICGC;COSMIC	16.704	Up-regulation
AGC_PKC_PKCa_PRKCA_ST	Q8WZ42	TTN	P17252	PRKCA	S7471	S7469F	7469	Missense	proximal	-2	no	17.534	16.863	EPSD	ICGC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	Q8WZ42	TTN	P17252	PRKCA	S7471	F7474L	7474	Missense	distal	3	no	17.534	17.201	EPSD	ICGC;COSMIC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	Q8WZ42	TTN	P17252	PRKCA	S7471	G7464R	7464	Missense	distal	-7	no	17.534	17.544	EPSD	ICGC;COSMIC	16.704	Up-regulation
AGC_PKC_PKCa_PRKCA_ST	Q8WZ42	TTN	P17252	PRKCA	S7471	P7477L	7477	Missense	distal	6	no	17.534	17.490	EPSD	ICGC;COSMIC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	Q8WZ42	TTN	P17252	PRKCA	S7471	S7469Y	7469	Missense	proximal	-2	no	17.534	18.108	EPSD	ICGC;COSMIC	16.704	Up-regulation
AGC_PKC_PKCa_PRKCA_ST	Q8WZ42	TTN	P17252	PRKCA	S7522	N7524K	7524	Missense	proximal	2	no	12.840	17.789	EPSD	ICGC	16.704	Gain
AGC_PKC_PKCa_PRKCA_ST	Q8WZ42	TTN	P17252	PRKCA	S7628	E7635K	7635	Missense	distal	7	no	17.767	17.913	EPSD	ICGC;COSMIC	16.704	Up-regulation
AGC_PKC_PKCa_PRKCA_ST	Q8WZ42	TTN	P17252	PRKCA	S7628	P7632A	7632	Missense	distal	4	no	17.767	17.983	EPSD	ICGC;COSMIC	16.704	Up-regulation
AGC_PKC_PKCa_PRKCA_ST	Q8WZ42	TTN	P17252	PRKCA	S7628	P7632T	7632	Missense	distal	4	no	17.767	17.536	EPSD	ICGC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	Q8WZ42	TTN	P17252	PRKCA	S7628	K7625I	7625	Missense	distal	-3	no	17.767	15.306	EPSD	ICGC;COSMIC	16.704	Loss
AGC_PKC_PKCa_PRKCA_ST	Q8WZ42	TTN	P17252	PRKCA	S7628	S7628F	7628	Missense	central	0	yes	17.767	0.000	EPSD	ICGC	16.704	Loss
AGC_PKC_PKCa_PRKCA_ST	Q8WZ42	TTN	P17252	PRKCA	S7628	A7634D	7634	Missense	distal	6	no	17.767	17.719	EPSD	ICGC;COSMIC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	Q8WZ42	TTN	P17252	PRKCA	S7628	P7632L	7632	Missense	distal	4	no	17.767	17.175	EPSD	ICGC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	Q8WZ42	TTN	P17252	PRKCA	S7628	P7632S	7632	Missense	distal	4	no	17.767	17.967	EPSD	ICGC;COSMIC	16.704	Up-regulation
AGC_PKC_PKCa_PRKCA_ST	Q8WZ42	TTN	P17252	PRKCA	S7637	E7635K	7635	Missense	proximal	-2	no	15.081	17.580	EPSD	ICGC;COSMIC	16.704	Gain
AGC_PKC_PKCa_PRKCA_ST	Q8WZ42	TTN	P17252	PRKCA	S7658	H7660R	7660	Missense	proximal	2	no	13.655	18.679	EPSD	ICGC;COSMIC	16.704	Gain
AGC_PKC_PKCa_PRKCA_ST	Q8WZ42	TTN	P17252	PRKCA	S8276	K8278T	8278	Missense	proximal	2	no	18.369	13.980	EPSD	ICGC;COSMIC	16.704	Loss
AGC_PKC_PKCa_PRKCA_ST	Q8WZ42	TTN	P17252	PRKCA	S8276	F8283I	8283	Missense	distal	7	no	18.369	18.279	EPSD	ICGC;COSMIC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	Q8WZ42	TTN	P17252	PRKCA	S8276	E8272K	8272	Missense	distal	-4	no	18.369	19.100	EPSD	ICGC;COSMIC	16.704	Up-regulation
AGC_PKC_PKCa_PRKCA_ST	Q8WZ42	TTN	P17252	PRKCA	S8276	E8270D	8270	Missense	distal	-6	no	18.369	18.286	EPSD	ICGC;COSMIC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	Q8WZ42	TTN	P17252	PRKCA	S8276	E8270K	8270	Missense	distal	-6	no	18.369	18.436	EPSD	ICGC;COSMIC	16.704	Up-regulation
AGC_PKC_PKCa_PRKCA_ST	Q8WZ42	TTN	P17252	PRKCA	S8543	E8541K	8541	Missense	proximal	-2	no	15.196	17.695	EPSD	ICGC;COSMIC	16.704	Gain
AGC_PKC_PKCa_PRKCA_ST	Q8WZ42	TTN	P17252	PRKCA	S8805	E8807K	8807	Missense	proximal	2	no	13.588	18.867	EPSD	ICGC	16.704	Gain
AGC_PKC_PKCa_PRKCA_ST	Q8WZ42	TTN	P17252	PRKCA	S9183	E9187K	9187	Missense	distal	4	no	16.177	16.716	EPSD	ICGC;COSMIC	16.704	Gain
AGC_PKC_PKCa_PRKCA_ST	Q8WZ42	TTN	P17252	PRKCA	S9559	R9558M	9558	Missense	proximal	-1	no	16.636	16.908	EPSD	ICGC;COSMIC	16.704	Gain
AGC_PKC_PKCa_PRKCA_ST	Q8WZ42	TTN	P17252	PRKCA	S9559	E9563K	9563	Missense	distal	4	no	16.636	17.175	EPSD	ICGC;COSMIC	16.704	Gain
AGC_PKC_PKCa_PRKCA_ST	Q8WZ42	TTN	P17252	PRKCA	S9559	E9565K	9565	Missense	distal	6	no	16.636	16.730	EPSD	ICGC;COSMIC;CCLE	16.704	Gain
AGC_PKC_PKCa_PRKCA_ST	Q8WZ42	TTN	P17252	PRKCA	S9559	D9562N	9562	Missense	distal	3	no	16.636	16.791	EPSD	ICGC;COSMIC	16.704	Gain
AGC_PKC_PKCa_PRKCA_ST	Q8WZ42	TTN	P17252	PRKCA	S9559	I9556M	9556	Missense	distal	-3	no	16.636	18.151	EPSD	ICGC;COSMIC	16.704	Gain
AGC_PKC_PKCa_PRKCA_ST	Q8WZ42	TTN	P17252	PRKCA	S9578	L9585R	9585	Missense	distal	7	no	16.839	16.882	EPSD	ICGC;CCLE	16.704	Up-regulation
AGC_PKC_PKCa_PRKCA_ST	Q8WZ42	TTN	P17252	PRKCA	S9803	E9799K	9799	Missense	distal	-4	no	16.678	17.409	EPSD	ICGC;COSMIC	16.704	Gain
AGC_PKC_PKCa_PRKCA_ST	Q8WZ42	TTN	P17252	PRKCA	S9803	Q9804R	9804	Missense	proximal	1	no	16.678	16.795	EPSD	ICGC;COSMIC	16.704	Gain
AGC_PKC_PKCa_PRKCA_ST	Q8WZ42	TTN	P17252	PRKCA	T9931	E9934K	9934	Missense	distal	3	no	16.423	17.039	EPSD	ICGC;COSMIC	16.704	Gain
AGC_PKC_PKCa_PRKCA_ST	Q8WZ42	TTN	P17252	PRKCA	T9970	T9970N	9970	Missense	central	0	yes	17.131	0.000	EPSD	ICGC;COSMIC	16.704	Loss
AGC_PKC_PKCa_PRKCA_ST	Q8WZ42	TTN	P17252	PRKCA	S10471	I10469V	10469	Missense	proximal	-2	no	16.261	17.007	EPSD	ICGC;COSMIC	16.704	Gain
AGC_PKC_PKCa_PRKCA_ST	Q8WZ42	TTN	P17252	PRKCA	S10781	T10783A	10783	Missense	proximal	2	no	17.301	17.413	EPSD	ICGC;COSMIC	16.704	Up-regulation
AGC_PKC_PKCa_PRKCA_ST	Q8WZ42	TTN	P17252	PRKCA	S10781	I10780T	10780	Missense	proximal	-1	no	17.301	18.206	EPSD	ICGC;COSMIC	16.704	Up-regulation
AGC_PKC_PKCa_PRKCA_ST	Q8WZ42	TTN	P17252	PRKCA	S10781	E10788Q	10788	Missense	distal	7	no	17.301	17.392	EPSD	ICGC;COSMIC	16.704	Up-regulation
AGC_PKC_PKCa_PRKCA_ST	Q8WZ42	TTN	P17252	PRKCA	S10781	R10779C	10779	Missense	proximal	-2	no	17.301	15.601	EPSD	ICGC;COSMIC	16.704	Loss
AGC_PKC_PKCa_PRKCA_ST	Q8WZ42	TTN	P17252	PRKCA	S10781	E10776D	10776	Missense	distal	-5	no	17.301	17.223	EPSD	ICGC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	Q8WZ42	TTN	P17252	PRKCA	S10781	E10786K	10786	Missense	distal	5	no	17.301	17.715	EPSD	ICGC;COSMIC	16.704	Up-regulation
AGC_PKC_PKCa_PRKCA_ST	Q8WZ42	TTN	P17252	PRKCA	S10781	E10788K	10788	Missense	distal	7	no	17.301	17.447	EPSD	ICGC	16.704	Up-regulation
AGC_PKC_PKCa_PRKCA_ST	Q8WZ42	TTN	P17252	PRKCA	S10781	E10776K	10776	Missense	distal	-5	no	17.301	17.595	EPSD	ICGC;COSMIC	16.704	Up-regulation
AGC_PKC_PKCa_PRKCA_ST	Q8WZ42	TTN	P17252	PRKCA	S10781	K10784E	10784	Missense	distal	3	no	17.301	16.685	EPSD	ICGC	16.704	Loss
AGC_PKC_PKCa_PRKCA_ST	Q8WZ42	TTN	P17252	PRKCA	S11223	V11222M	11222	Missense	proximal	-1	no	16.228	18.350	EPSD	ICGC;COSMIC	16.704	Gain
AGC_PKC_PKCa_PRKCA_ST	Q8WZ42	TTN	P17252	PRKCA	S12022	G12021E	12021	Missense	proximal	-1	no	17.554	17.325	PhosphoSitePlus;EPSD	ICGC;COSMIC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	Q8WZ42	TTN	P17252	PRKCA	S12022	P12027H	12027	Missense	distal	5	no	17.554	17.277	PhosphoSitePlus;EPSD	ICGC;COSMIC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	Q8WZ42	TTN	P17252	PRKCA	S12022	P12027T	12027	Missense	distal	5	no	17.554	17.219	PhosphoSitePlus;EPSD	ICGC;COSMIC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	Q8WZ42	TTN	P17252	PRKCA	S12088	R12092M	12092	Missense	distal	4	no	22.860	22.664	EPSD	ICGC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	Q8WZ42	TTN	P17252	PRKCA	S12088	D12081E	12081	Missense	distal	-7	no	22.860	22.857	EPSD	ICGC;COSMIC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	Q8WZ42	TTN	P17252	PRKCA	S12088	F12093L	12093	Missense	distal	5	no	22.860	22.636	EPSD	ICGC;COSMIC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	Q8WZ42	TTN	P17252	PRKCA	S12491	K12488N	12488	Missense	distal	-3	no	19.668	17.467	EPSD	ICGC;COSMIC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	Q8WZ42	TTN	P17252	PRKCA	S12491	R12493W	12493	Missense	proximal	2	no	19.668	14.228	EPSD	ICGC;COSMIC	16.704	Loss
AGC_PKC_PKCa_PRKCA_ST	Q8WZ42	TTN	P17252	PRKCA	S12491	R12493Q	12493	Missense	proximal	2	no	19.668	15.833	EPSD	ICGC;COSMIC	16.704	Loss
AGC_PKC_PKCa_PRKCA_ST	Q8WZ42	TTN	P17252	PRKCA	S12491	G12498S	12498	Missense	distal	7	no	19.668	19.646	EPSD	ICGC;COSMIC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	Q8WZ42	TTN	P17252	PRKCA	S12505	F12503C	12503	Missense	proximal	-2	no	15.513	17.786	EPSD	ICGC	16.704	Gain
AGC_PKC_PKCa_PRKCA_ST	Q8WZ42	TTN	P17252	PRKCA	S12635	I12628V	12628	Missense	distal	-7	no	18.921	18.922	EPSD	ICGC;COSMIC	16.704	Up-regulation
AGC_PKC_PKCa_PRKCA_ST	Q8WZ42	TTN	P17252	PRKCA	S12635	R12642C	12642	Missense	distal	7	no	18.921	18.697	EPSD	ICGC;COSMIC;CCLE	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	Q8WZ42	TTN	P17252	PRKCA	S12635	P12630A	12630	Missense	distal	-5	no	18.921	18.542	EPSD	ICGC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	Q8WZ42	TTN	P17252	PRKCA	T12866	E12869D	12869	Missense	distal	3	no	16.705	16.218	EPSD	ICGC;COSMIC	16.704	Loss
AGC_PKC_PKCa_PRKCA_ST	Q8WZ42	TTN	P17252	PRKCA	T12866	E12871K	12871	Missense	distal	5	no	16.705	17.119	EPSD	ICGC;COSMIC	16.704	Up-regulation
AGC_PKC_PKCa_PRKCA_ST	Q8WZ42	TTN	P17252	PRKCA	T12866	P12861S	12861	Missense	distal	-5	no	16.705	16.379	EPSD	ICGC;COSMIC	16.704	Loss
AGC_PKC_PKCa_PRKCA_ST	Q8WZ42	TTN	P17252	PRKCA	S12911	E12906K	12906	Missense	distal	-5	no	18.194	18.489	EPSD	ICGC;COSMIC	16.704	Up-regulation
AGC_PKC_PKCa_PRKCA_ST	Q8WZ42	TTN	P17252	PRKCA	S12911	K12915E	12915	Missense	distal	4	no	18.194	17.655	EPSD	ICGC;COSMIC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	Q8WZ42	TTN	P17252	PRKCA	S12911	G12907E	12907	Missense	distal	-4	no	18.194	17.600	EPSD	ICGC;COSMIC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	Q8WZ42	TTN	P17252	PRKCA	S12911	S12911L	12911	Missense	central	0	yes	18.194	0.000	EPSD	ICGC;COSMIC	16.704	Loss
AGC_PKC_PKCa_PRKCA_ST	Q8WZ42	TTN	P17252	PRKCA	S12911	I12912T	12912	Missense	proximal	1	no	18.194	16.859	EPSD	ICGC;COSMIC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	Q8WZ42	TTN	P17252	PRKCA	S12911	S12911P	12911	Missense	central	0	yes	18.194	0.000	EPSD	ICGC;COSMIC	16.704	Loss
AGC_PKC_PKCa_PRKCA_ST	Q8WZ42	TTN	P17252	PRKCA	S13707	K13712T	13712	Missense	distal	5	no	19.302	18.841	EPSD	ICGC;COSMIC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	Q8WZ42	TTN	P17252	PRKCA	S13707	P13701H	13701	Missense	distal	-6	no	19.302	19.339	EPSD	ICGC;COSMIC	16.704	Up-regulation
AGC_PKC_PKCa_PRKCA_ST	Q8WZ42	TTN	P17252	PRKCA	S13707	K13714M	13714	Missense	distal	7	no	19.302	19.216	EPSD	ICGC;COSMIC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	Q8WZ42	TTN	P17252	PRKCA	S13707	R13705C	13705	Missense	proximal	-2	no	19.302	17.602	EPSD	ICGC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	Q8WZ42	TTN	P17252	PRKCA	S13802	H13804Q	13804	Missense	proximal	2	no	15.592	16.782	EPSD	ICGC	16.704	Gain
AGC_PKC_PKCa_PRKCA_ST	Q8WZ42	TTN	P17252	PRKCA	S13980	T13975M	13975	Missense	distal	-5	no	17.668	17.600	EPSD	ICGC;COSMIC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	Q8WZ42	TTN	P17252	PRKCA	S13980	Q13978H	13978	Missense	proximal	-2	no	17.668	14.873	EPSD	ICGC;COSMIC	16.704	Loss
AGC_PKC_PKCa_PRKCA_ST	Q8WZ42	TTN	P17252	PRKCA	S13980	K13987N	13987	Missense	distal	7	no	17.668	17.547	EPSD	ICGC;COSMIC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	Q8WZ42	TTN	P17252	PRKCA	S14387	E14385K	14385	Missense	proximal	-2	no	17.851	20.350	EPSD	ICGC;COSMIC	16.704	Up-regulation
AGC_PKC_PKCa_PRKCA_ST	Q8WZ42	TTN	P17252	PRKCA	S14387	R14386C	14386	Missense	proximal	-1	no	17.851	15.191	EPSD	ICGC;COSMIC	16.704	Loss
AGC_PKC_PKCa_PRKCA_ST	Q8WZ42	TTN	P17252	PRKCA	S14387	I14381M	14381	Missense	distal	-6	no	17.851	17.945	EPSD	ICGC	16.704	Up-regulation
AGC_PKC_PKCa_PRKCA_ST	Q8WZ42	TTN	P17252	PRKCA	T14402	S14404T	14404	Missense	proximal	2	no	17.086	16.896	EPSD	ICGC;COSMIC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	Q8WZ42	TTN	P17252	PRKCA	T14402	E14406K	14406	Missense	distal	4	no	17.086	17.625	EPSD	ICGC;COSMIC	16.704	Up-regulation
AGC_PKC_PKCa_PRKCA_ST	Q8WZ42	TTN	P17252	PRKCA	S14457	R14454P	14454	Missense	distal	-3	no	17.800	13.951	EPSD	ICGC;COSMIC	16.704	Loss
AGC_PKC_PKCa_PRKCA_ST	Q8WZ42	TTN	P17252	PRKCA	S14457	R14454Q	14454	Missense	distal	-3	no	17.800	14.942	EPSD	ICGC;COSMIC	16.704	Loss
AGC_PKC_PKCa_PRKCA_ST	Q8WZ42	TTN	P17252	PRKCA	S14457	K14463T	14463	Missense	distal	6	no	17.800	17.692	EPSD	ICGC;COSMIC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	Q8WZ42	TTN	P17252	PRKCA	S14457	V14450I	14450	Missense	distal	-7	no	17.800	17.799	EPSD	ICGC;COSMIC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	Q8WZ42	TTN	P17252	PRKCA	S14457	E14455D	14455	Missense	proximal	-2	no	17.800	18.508	EPSD	ICGC;COSMIC;CCLE	16.704	Up-regulation
AGC_PKC_PKCa_PRKCA_ST	Q8WZ42	TTN	P17252	PRKCA	S14558	C14554Y	14554	Missense	distal	-4	no	16.332	17.289	EPSD	ICGC;COSMIC	16.704	Gain
AGC_PKC_PKCa_PRKCA_ST	Q8WZ42	TTN	P17252	PRKCA	S14558	D14559G	14559	Missense	proximal	1	no	16.332	16.978	EPSD	ICGC;COSMIC	16.704	Gain
AGC_PKC_PKCa_PRKCA_ST	Q8WZ42	TTN	P17252	PRKCA	S14680	V14675A	14675	Missense	distal	-5	no	17.367	17.451	EPSD	ICGC;COSMIC	16.704	Up-regulation
AGC_PKC_PKCa_PRKCA_ST	Q8WZ42	TTN	P17252	PRKCA	S14680	G14686D	14686	Missense	distal	6	no	17.367	17.427	EPSD	ICGC;COSMIC	16.704	Up-regulation
AGC_PKC_PKCa_PRKCA_ST	Q8WZ42	TTN	P17252	PRKCA	S14680	D14684E	14684	Missense	distal	4	no	17.367	17.597	EPSD	ICGC	16.704	Up-regulation
AGC_PKC_PKCa_PRKCA_ST	Q8WZ42	TTN	P17252	PRKCA	S14680	T14687P	14687	Missense	distal	7	no	17.367	17.396	EPSD	ICGC	16.704	Up-regulation
AGC_PKC_PKCa_PRKCA_ST	Q8WZ42	TTN	P17252	PRKCA	T14868	K14865N	14865	Missense	distal	-3	no	16.744	14.543	EPSD	ICGC	16.704	Loss
AGC_PKC_PKCa_PRKCA_ST	Q8WZ42	TTN	P17252	PRKCA	T14868	Y14869N	14869	Missense	proximal	1	no	16.744	15.980	EPSD	ICGC;COSMIC	16.704	Loss
AGC_PKC_PKCa_PRKCA_ST	Q8WZ42	TTN	P17252	PRKCA	T14868	K14861E	14861	Missense	distal	-7	no	16.744	16.736	EPSD	ICGC;COSMIC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	Q8WZ42	TTN	P17252	PRKCA	T14868	G14873S	14873	Missense	distal	5	no	16.744	16.883	EPSD	ICGC;COSMIC	16.704	Up-regulation
AGC_PKC_PKCa_PRKCA_ST	Q8WZ42	TTN	P17252	PRKCA	T14868	T14868A	14868	Missense	central	0	yes	16.744	0.000	EPSD	ICGC;COSMIC	16.704	Loss
AGC_PKC_PKCa_PRKCA_ST	Q8WZ42	TTN	P17252	PRKCA	T14868	D14866G	14866	Missense	proximal	-2	no	16.744	17.290	EPSD	ICGC	16.704	Up-regulation
AGC_PKC_PKCa_PRKCA_ST	Q8WZ42	TTN	P17252	PRKCA	T14875	R14881I	14881	Missense	distal	6	no	19.545	19.439	EPSD	ICGC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	Q8WZ42	TTN	P17252	PRKCA	T14875	Y14869N	14869	Missense	distal	-6	no	19.545	19.541	EPSD	ICGC;COSMIC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	Q8WZ42	TTN	P17252	PRKCA	T14875	G14873S	14873	Missense	proximal	-2	no	19.545	19.115	EPSD	ICGC;COSMIC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	Q8WZ42	TTN	P17252	PRKCA	T14875	T14868A	14868	Missense	distal	-7	no	19.545	19.549	EPSD	ICGC;COSMIC	16.704	Up-regulation
AGC_PKC_PKCa_PRKCA_ST	Q8WZ42	TTN	P17252	PRKCA	T14875	K14877N	14877	Missense	proximal	2	no	19.545	14.596	EPSD	ICGC	16.704	Loss
AGC_PKC_PKCa_PRKCA_ST	Q8WZ42	TTN	P17252	PRKCA	S14926	S14926P	14926	Missense	central	0	yes	17.840	0.000	EPSD	ICGC	16.704	Loss
AGC_PKC_PKCa_PRKCA_ST	Q8WZ42	TTN	P17252	PRKCA	S14926	V14927G	14927	Missense	proximal	1	no	17.840	17.109	EPSD	ICGC;COSMIC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	Q8WZ42	TTN	P17252	PRKCA	S14926	D14921Y	14921	Missense	distal	-5	no	17.840	17.716	EPSD	ICGC;COSMIC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	Q8WZ42	TTN	P17252	PRKCA	S15263	E15256K	15256	Missense	distal	-7	no	18.264	18.272	EPSD	ICGC;COSMIC	16.704	Up-regulation
AGC_PKC_PKCa_PRKCA_ST	Q8WZ42	TTN	P17252	PRKCA	S15357	T15361K	15361	Missense	distal	4	no	16.509	17.357	EPSD	ICGC	16.704	Gain
AGC_PKC_PKCa_PRKCA_ST	Q8WZ42	TTN	P17252	PRKCA	T15361	T15361K	15361	Missense	central	0	yes	18.033	0.000	EPSD	ICGC	16.704	Loss
AGC_PKC_PKCa_PRKCA_ST	Q8WZ42	TTN	P17252	PRKCA	T15361	M15362I	15362	Missense	proximal	1	no	18.033	19.084	EPSD	ICGC;COSMIC	16.704	Up-regulation
AGC_PKC_PKCa_PRKCA_ST	Q8WZ42	TTN	P17252	PRKCA	T15361	D15365N	15365	Missense	distal	4	no	18.033	17.676	EPSD	ICGC;COSMIC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	Q8WZ42	TTN	P17252	PRKCA	T15361	S15357I	15357	Missense	distal	-4	no	18.033	17.591	EPSD	ICGC;COSMIC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	Q8WZ42	TTN	P17252	PRKCA	T15361	K15363T	15363	Missense	proximal	2	no	18.033	13.645	EPSD	ICGC;COSMIC	16.704	Loss
AGC_PKC_PKCa_PRKCA_ST	Q8WZ42	TTN	P17252	PRKCA	S15394	K15391R	15391	Missense	distal	-3	no	14.698	16.724	EPSD	ICGC;COSMIC	16.704	Gain
AGC_PKC_PKCa_PRKCA_ST	Q8WZ42	TTN	P17252	PRKCA	S15398	N15400K	15400	Missense	proximal	2	no	13.175	18.124	EPSD	ICGC;COSMIC	16.704	Gain
AGC_PKC_PKCa_PRKCA_ST	Q8WZ42	TTN	P17252	PRKCA	S15615	E15617Q	15617	Missense	proximal	2	no	15.234	17.100	EPSD	ICGC;COSMIC	16.704	Gain
AGC_PKC_PKCa_PRKCA_ST	Q8WZ42	TTN	P17252	PRKCA	S15682	N15685K	15685	Missense	distal	3	no	17.184	18.131	EPSD	ICGC;COSMIC	16.704	Up-regulation
AGC_PKC_PKCa_PRKCA_ST	Q8WZ42	TTN	P17252	PRKCA	S15682	P15676T	15676	Missense	distal	-6	no	17.184	17.090	EPSD	ICGC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	Q8WZ42	TTN	P17252	PRKCA	S15682	P15676H	15676	Missense	distal	-6	no	17.184	17.221	EPSD	ICGC;COSMIC	16.704	Up-regulation
AGC_PKC_PKCa_PRKCA_ST	Q8WZ42	TTN	P17252	PRKCA	S15682	G15689R	15689	Missense	distal	7	no	17.184	17.208	EPSD	ICGC;COSMIC	16.704	Up-regulation
AGC_PKC_PKCa_PRKCA_ST	Q8WZ42	TTN	P17252	PRKCA	S15682	I15683T	15683	Missense	proximal	1	no	17.184	15.848	EPSD	ICGC;COSMIC	16.704	Loss
AGC_PKC_PKCa_PRKCA_ST	Q8WZ42	TTN	P17252	PRKCA	S15686	N15685K	15685	Missense	proximal	-1	no	19.282	19.884	EPSD	ICGC;COSMIC	16.704	Up-regulation
AGC_PKC_PKCa_PRKCA_ST	Q8WZ42	TTN	P17252	PRKCA	S15686	Q15692K	15692	Missense	distal	6	no	19.282	19.393	EPSD	ICGC;COSMIC	16.704	Up-regulation
AGC_PKC_PKCa_PRKCA_ST	Q8WZ42	TTN	P17252	PRKCA	S15686	G15689R	15689	Missense	distal	3	no	19.282	19.922	EPSD	ICGC;COSMIC	16.704	Up-regulation
AGC_PKC_PKCa_PRKCA_ST	Q8WZ42	TTN	P17252	PRKCA	S15686	I15683T	15683	Missense	distal	-3	no	19.282	19.606	EPSD	ICGC;COSMIC	16.704	Up-regulation
AGC_PKC_PKCa_PRKCA_ST	Q8WZ42	TTN	P17252	PRKCA	S15691	R15694H	15694	Missense	distal	3	no	16.883	16.171	EPSD	ICGC;COSMIC	16.704	Loss
AGC_PKC_PKCa_PRKCA_ST	Q8WZ42	TTN	P17252	PRKCA	S15691	N15685K	15685	Missense	distal	-6	no	16.883	17.007	EPSD	ICGC;COSMIC	16.704	Up-regulation
AGC_PKC_PKCa_PRKCA_ST	Q8WZ42	TTN	P17252	PRKCA	S15691	S15698Y	15698	Missense	distal	7	no	16.883	16.877	EPSD	ICGC;COSMIC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	Q8WZ42	TTN	P17252	PRKCA	S15691	R15694C	15694	Missense	distal	3	no	16.883	14.265	EPSD	ICGC;COSMIC	16.704	Loss
AGC_PKC_PKCa_PRKCA_ST	Q8WZ42	TTN	P17252	PRKCA	S15691	Q15692K	15692	Missense	proximal	1	no	16.883	17.037	EPSD	ICGC;COSMIC	16.704	Up-regulation
AGC_PKC_PKCa_PRKCA_ST	Q8WZ42	TTN	P17252	PRKCA	S15691	V15695I	15695	Missense	distal	4	no	16.883	16.760	EPSD	ICGC;CCLE	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	Q8WZ42	TTN	P17252	PRKCA	S15691	G15689R	15689	Missense	proximal	-2	no	16.883	19.755	EPSD	ICGC;COSMIC	16.704	Up-regulation
AGC_PKC_PKCa_PRKCA_ST	Q8WZ42	TTN	P17252	PRKCA	S15691	R15696L	15696	Missense	distal	5	no	16.883	16.551	EPSD	ICGC;COSMIC	16.704	Loss
AGC_PKC_PKCa_PRKCA_ST	Q8WZ42	TTN	P17252	PRKCA	S15744	S15744P	15744	Missense	central	0	yes	16.939	0.000	EPSD	ICGC;COSMIC	16.704	Loss
AGC_PKC_PKCa_PRKCA_ST	Q8WZ42	TTN	P17252	PRKCA	S15744	K15742N	15742	Missense	proximal	-2	no	16.939	15.370	EPSD	ICGC;COSMIC	16.704	Loss
AGC_PKC_PKCa_PRKCA_ST	Q8WZ42	TTN	P17252	PRKCA	S15744	D15739Y	15739	Missense	distal	-5	no	16.939	16.815	EPSD	ICGC;COSMIC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	Q8WZ42	TTN	P17252	PRKCA	S15744	T15743A	15743	Missense	proximal	-1	no	16.939	16.758	EPSD	ICGC;COSMIC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	Q8WZ42	TTN	P17252	PRKCA	S15744	L15746I	15746	Missense	proximal	2	no	16.939	16.894	EPSD	ICGC;COSMIC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	Q8WZ42	TTN	P17252	PRKCA	S15872	H15874R	15874	Missense	proximal	2	no	11.874	16.898	EPSD	ICGC	16.704	Gain
AGC_PKC_PKCa_PRKCA_ST	Q8WZ42	TTN	P17252	PRKCA	S15876	H15874R	15874	Missense	proximal	-2	no	12.175	16.728	EPSD	ICGC	16.704	Gain
AGC_PKC_PKCa_PRKCA_ST	Q8WZ42	TTN	P17252	PRKCA	T15989	V15990I	15990	Missense	proximal	1	no	19.994	20.705	EPSD	ICGC;COSMIC	16.704	Up-regulation
AGC_PKC_PKCa_PRKCA_ST	Q8WZ42	TTN	P17252	PRKCA	T15989	R15986L	15986	Missense	distal	-3	no	19.994	15.638	EPSD	ICGC;COSMIC	16.704	Loss
AGC_PKC_PKCa_PRKCA_ST	Q8WZ42	TTN	P17252	PRKCA	T15989	T15989I	15989	Missense	central	0	yes	19.994	0.000	EPSD	ICGC;COSMIC	16.704	Loss
AGC_PKC_PKCa_PRKCA_ST	Q8WZ42	TTN	P17252	PRKCA	S16111	G16110S	16110	Missense	proximal	-1	no	16.986	16.738	EPSD	ICGC;COSMIC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	Q8WZ42	TTN	P17252	PRKCA	S16111	A16114P	16114	Missense	distal	3	no	16.986	17.053	EPSD	ICGC;COSMIC	16.704	Up-regulation
AGC_PKC_PKCa_PRKCA_ST	Q8WZ42	TTN	P17252	PRKCA	S16111	S16108R	16108	Missense	distal	-3	no	16.986	19.856	EPSD	ICGC	16.704	Up-regulation
AGC_PKC_PKCa_PRKCA_ST	Q8WZ42	TTN	P17252	PRKCA	S16329	R16331Q	16331	Missense	proximal	2	no	20.986	17.151	EPSD	ICGC;COSMIC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	Q8WZ42	TTN	P17252	PRKCA	S16329	R16327C	16327	Missense	proximal	-2	no	20.986	19.286	EPSD	ICGC;COSMIC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	Q8WZ42	TTN	P17252	PRKCA	S16329	S16329R	16329	Missense	central	0	yes	20.986	0.000	EPSD	ICGC;COSMIC	16.704	Loss
AGC_PKC_PKCa_PRKCA_ST	Q8WZ42	TTN	P17252	PRKCA	S16329	R16331L	16331	Missense	proximal	2	no	20.986	15.999	EPSD	ICGC;COSMIC	16.704	Loss
AGC_PKC_PKCa_PRKCA_ST	Q8WZ42	TTN	P17252	PRKCA	S16329	T16323S	16323	Missense	distal	-6	no	20.986	21.111	EPSD	ICGC;COSMIC	16.704	Up-regulation
AGC_PKC_PKCa_PRKCA_ST	Q8WZ42	TTN	P17252	PRKCA	S16329	R16327H	16327	Missense	proximal	-2	no	20.986	16.432	EPSD	ICGC;COSMIC	16.704	Loss
AGC_PKC_PKCa_PRKCA_ST	Q8WZ42	TTN	P17252	PRKCA	S16329	P16322S	16322	Missense	distal	-7	no	20.986	20.988	EPSD	ICGC;COSMIC	16.704	Up-regulation
AGC_PKC_PKCa_PRKCA_ST	Q8WZ42	TTN	P17252	PRKCA	S16329	G16332E	16332	Missense	distal	3	no	20.986	20.387	EPSD	ICGC;COSMIC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	Q8WZ42	TTN	P17252	PRKCA	S16329	P16322Q	16322	Missense	distal	-7	no	20.986	20.985	EPSD	ICGC;COSMIC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	Q8WZ42	TTN	P17252	PRKCA	T16334	R16331Q	16331	Missense	distal	-3	no	18.620	15.762	EPSD	ICGC;COSMIC	16.704	Loss
AGC_PKC_PKCa_PRKCA_ST	Q8WZ42	TTN	P17252	PRKCA	T16334	R16327C	16327	Missense	distal	-7	no	18.620	18.601	EPSD	ICGC;COSMIC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	Q8WZ42	TTN	P17252	PRKCA	T16334	S16329R	16329	Missense	distal	-5	no	18.620	19.047	EPSD	ICGC;COSMIC	16.704	Up-regulation
AGC_PKC_PKCa_PRKCA_ST	Q8WZ42	TTN	P17252	PRKCA	T16334	A16339E	16339	Missense	distal	5	no	18.620	18.388	EPSD	ICGC;COSMIC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	Q8WZ42	TTN	P17252	PRKCA	T16334	R16331L	16331	Missense	distal	-3	no	18.620	14.264	EPSD	ICGC;COSMIC	16.704	Loss
AGC_PKC_PKCa_PRKCA_ST	Q8WZ42	TTN	P17252	PRKCA	T16334	A16339V	16339	Missense	distal	5	no	18.620	18.236	EPSD	ICGC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	Q8WZ42	TTN	P17252	PRKCA	T16334	R16327H	16327	Missense	distal	-7	no	18.620	18.613	EPSD	ICGC;COSMIC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	Q8WZ42	TTN	P17252	PRKCA	T16334	G16332E	16332	Missense	proximal	-2	no	18.620	17.366	EPSD	ICGC;COSMIC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	Q8WZ42	TTN	P17252	PRKCA	T16334	K16338N	16338	Missense	distal	4	no	18.620	17.493	EPSD	ICGC;COSMIC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	Q8WZ42	TTN	P17252	PRKCA	S16412	V16419I	16419	Missense	distal	7	no	18.070	17.973	EPSD	ICGC;COSMIC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	Q8WZ42	TTN	P17252	PRKCA	S16412	R16415Q	16415	Missense	distal	3	no	18.070	15.617	EPSD	ICGC;COSMIC	16.704	Loss
AGC_PKC_PKCa_PRKCA_ST	Q8WZ42	TTN	P17252	PRKCA	S16412	R16415P	16415	Missense	distal	3	no	18.070	16.539	EPSD	ICGC;COSMIC	16.704	Loss
AGC_PKC_PKCa_PRKCA_ST	Q8WZ42	TTN	P17252	PRKCA	S16412	G16411D	16411	Missense	proximal	-1	no	18.070	17.327	EPSD	ICGC;COSMIC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	Q8WZ42	TTN	P17252	PRKCA	S16412	N16408D	16408	Missense	distal	-4	no	18.070	17.722	EPSD	ICGC;COSMIC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	Q8WZ42	TTN	P17252	PRKCA	S16412	H16418Q	16418	Missense	distal	6	no	18.070	18.025	EPSD	ICGC;COSMIC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	Q8WZ42	TTN	P17252	PRKCA	S16412	V16413L	16413	Missense	proximal	1	no	18.070	17.945	EPSD	ICGC;COSMIC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	Q8WZ42	TTN	P17252	PRKCA	S16647	T16644R	16644	Missense	distal	-3	no	15.095	19.258	EPSD	ICGC;COSMIC	16.704	Gain
AGC_PKC_PKCa_PRKCA_ST	Q8WZ42	TTN	P17252	PRKCA	S16854	V16847A	16847	Missense	distal	-7	no	18.253	18.263	EPSD	ICGC;COSMIC	16.704	Up-regulation
AGC_PKC_PKCa_PRKCA_ST	Q8WZ42	TTN	P17252	PRKCA	S16854	R16852K	16852	Missense	proximal	-2	no	18.253	16.625	EPSD	ICGC;COSMIC	16.704	Loss
AGC_PKC_PKCa_PRKCA_ST	Q8WZ42	TTN	P17252	PRKCA	S16858	R16852K	16852	Missense	distal	-6	no	21.658	21.651	EPSD	ICGC;COSMIC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	Q8WZ42	TTN	P17252	PRKCA	S16858	D16865N	16865	Missense	distal	7	no	21.658	21.632	EPSD	ICGC;COSMIC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	Q8WZ42	TTN	P17252	PRKCA	S16858	D16864N	16864	Missense	distal	6	no	21.658	21.574	EPSD	ICGC;COSMIC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	Q8WZ42	TTN	P17252	PRKCA	T16931	T16926S	16926	Missense	distal	-5	no	22.219	21.891	EPSD	ICGC;COSMIC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	Q8WZ42	TTN	P17252	PRKCA	T16931	P16935L	16935	Missense	distal	4	no	22.219	21.627	EPSD	ICGC;COSMIC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	Q8WZ42	TTN	P17252	PRKCA	T16931	T16930N	16930	Missense	proximal	-1	no	22.219	22.440	EPSD	ICGC	16.704	Up-regulation
AGC_PKC_PKCa_PRKCA_ST	Q8WZ42	TTN	P17252	PRKCA	T16931	Y16937N	16937	Missense	distal	6	no	22.219	22.098	EPSD	ICGC;COSMIC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	Q8WZ42	TTN	P17252	PRKCA	T16931	R16933G	16933	Missense	proximal	2	no	22.219	16.974	EPSD	ICGC;CCLE	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	Q8WZ42	TTN	P17252	PRKCA	T16931	P16935S	16935	Missense	distal	4	no	22.219	22.419	EPSD	ICGC	16.704	Up-regulation
AGC_PKC_PKCa_PRKCA_ST	Q8WZ42	TTN	P17252	PRKCA	T16931	E16925K	16925	Missense	distal	-6	no	22.219	22.286	EPSD	ICGC;COSMIC	16.704	Up-regulation
AGC_PKC_PKCa_PRKCA_ST	Q8WZ42	TTN	P17252	PRKCA	T16931	I16936V	16936	Missense	distal	5	no	22.219	22.132	EPSD	ICGC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	Q8WZ42	TTN	P17252	PRKCA	S17116	R17114H	17114	Missense	proximal	-2	no	19.246	14.693	EPSD	ICGC	16.704	Loss
AGC_PKC_PKCa_PRKCA_ST	Q8WZ42	TTN	P17252	PRKCA	S17116	R17114C	17114	Missense	proximal	-2	no	19.246	17.546	EPSD	ICGC;COSMIC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	Q8WZ42	TTN	P17252	PRKCA	S17116	T17118S	17118	Missense	proximal	2	no	19.246	19.437	EPSD	ICGC;COSMIC	16.704	Up-regulation
AGC_PKC_PKCa_PRKCA_ST	Q8WZ42	TTN	P17252	PRKCA	S17116	Y17121H	17121	Missense	distal	5	no	19.246	19.101	EPSD	ICGC;COSMIC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	Q8WZ42	TTN	P17252	PRKCA	S17116	R17114S	17114	Missense	proximal	-2	no	19.246	15.944	EPSD	ICGC;COSMIC	16.704	Loss
AGC_PKC_PKCa_PRKCA_ST	Q8WZ42	TTN	P17252	PRKCA	S17133	E17135K	17135	Missense	proximal	2	no	13.393	18.673	EPSD	ICGC;COSMIC;CCLE	16.704	Gain
AGC_PKC_PKCa_PRKCA_ST	Q8WZ42	TTN	P17252	PRKCA	T17341	D17338G	17338	Missense	distal	-3	no	15.291	17.071	EPSD	ICGC;COSMIC	16.704	Gain
AGC_PKC_PKCa_PRKCA_ST	Q8WZ42	TTN	P17252	PRKCA	S17456	A17455D	17455	Missense	proximal	-1	no	17.006	17.070	EPSD	ICGC;COSMIC	16.704	Up-regulation
AGC_PKC_PKCa_PRKCA_ST	Q8WZ42	TTN	P17252	PRKCA	S17456	A17455T	17455	Missense	proximal	-1	no	17.006	17.187	EPSD	ICGC	16.704	Up-regulation
AGC_PKC_PKCa_PRKCA_ST	Q8WZ42	TTN	P17252	PRKCA	S17515	V17519I	17519	Missense	distal	4	no	16.910	16.787	EPSD	ICGC;COSMIC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	Q8WZ42	TTN	P17252	PRKCA	S17515	S17515N	17515	Missense	central	0	yes	16.910	0.000	EPSD	ICGC	16.704	Loss
AGC_PKC_PKCa_PRKCA_ST	Q8WZ42	TTN	P17252	PRKCA	S17515	S17521Y	17521	Missense	distal	6	no	16.910	16.929	EPSD	ICGC;COSMIC	16.704	Up-regulation
AGC_PKC_PKCa_PRKCA_ST	Q8WZ42	TTN	P17252	PRKCA	S17515	K17510N	17510	Missense	distal	-5	no	16.910	16.567	EPSD	ICGC;COSMIC	16.704	Loss
AGC_PKC_PKCa_PRKCA_ST	Q8WZ42	TTN	P17252	PRKCA	S17515	L17522I	17522	Missense	distal	7	no	16.910	16.754	EPSD	ICGC;COSMIC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	Q8WZ42	TTN	P17252	PRKCA	S17515	G17518D	17518	Missense	distal	3	no	16.910	15.824	EPSD	ICGC;COSMIC	16.704	Loss
AGC_PKC_PKCa_PRKCA_ST	Q8WZ42	TTN	P17252	PRKCA	S17700	V17693A	17693	Missense	distal	-7	no	17.741	17.751	EPSD	ICGC	16.704	Up-regulation
AGC_PKC_PKCa_PRKCA_ST	Q8WZ42	TTN	P17252	PRKCA	S17700	Y17703C	17703	Missense	distal	3	no	17.741	17.390	EPSD	ICGC;COSMIC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	Q8WZ42	TTN	P17252	PRKCA	S17770	G17767S	17767	Missense	distal	-3	no	18.529	18.921	EPSD	ICGC;COSMIC	16.704	Up-regulation
AGC_PKC_PKCa_PRKCA_ST	Q8WZ42	TTN	P17252	PRKCA	S17770	T17766N	17766	Missense	distal	-4	no	18.529	18.861	EPSD	ICGC;COSMIC	16.704	Up-regulation
AGC_PKC_PKCa_PRKCA_ST	Q8WZ42	TTN	P17252	PRKCA	S17826	T17824I	17824	Missense	proximal	-2	no	18.752	18.057	EPSD	ICGC;COSMIC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	Q8WZ42	TTN	P17252	PRKCA	S17826	E17821D	17821	Missense	distal	-5	no	18.752	18.674	EPSD	ICGC;COSMIC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	Q8WZ42	TTN	P17252	PRKCA	S17826	T17824K	17824	Missense	proximal	-2	no	18.752	20.018	EPSD	ICGC;COSMIC	16.704	Up-regulation
AGC_PKC_PKCa_PRKCA_ST	Q8WZ42	TTN	P17252	PRKCA	S17826	V17820M	17820	Missense	distal	-6	no	18.752	18.862	EPSD	ICGC;COSMIC	16.704	Up-regulation
AGC_PKC_PKCa_PRKCA_ST	Q8WZ42	TTN	P17252	PRKCA	S17826	Q17832H	17832	Missense	distal	6	no	18.752	18.797	EPSD	ICGC;COSMIC	16.704	Up-regulation
AGC_PKC_PKCa_PRKCA_ST	Q8WZ42	TTN	P17252	PRKCA	S17826	R17827T	17827	Missense	proximal	1	no	18.752	17.905	EPSD	ICGC;COSMIC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	Q8WZ42	TTN	P17252	PRKCA	S17826	V17820L	17820	Missense	distal	-6	no	18.752	18.800	EPSD	ICGC;COSMIC	16.704	Up-regulation
AGC_PKC_PKCa_PRKCA_ST	Q8WZ42	TTN	P17252	PRKCA	S17929	R17935C	17935	Missense	distal	6	no	17.848	17.609	EPSD	ICGC;COSMIC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	Q8WZ42	TTN	P17252	PRKCA	S17929	L17925M	17925	Missense	distal	-4	no	17.848	18.551	EPSD	ICGC;COSMIC	16.704	Up-regulation
AGC_PKC_PKCa_PRKCA_ST	Q8WZ42	TTN	P17252	PRKCA	S17929	F17936I	17936	Missense	distal	7	no	17.848	17.758	EPSD	ICGC;COSMIC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	Q8WZ42	TTN	P17252	PRKCA	S17929	M17930I	17930	Missense	proximal	1	no	17.848	18.899	EPSD	ICGC;COSMIC	16.704	Up-regulation
AGC_PKC_PKCa_PRKCA_ST	Q8WZ42	TTN	P17252	PRKCA	S17929	V17926M	17926	Missense	distal	-3	no	17.848	18.566	EPSD	ICGC;COSMIC	16.704	Up-regulation
AGC_PKC_PKCa_PRKCA_ST	Q8WZ42	TTN	P17252	PRKCA	S17929	S17929L	17929	Missense	central	0	yes	17.848	0.000	EPSD	ICGC;COSMIC	16.704	Loss
AGC_PKC_PKCa_PRKCA_ST	Q8WZ42	TTN	P17252	PRKCA	S17929	S17929P	17929	Missense	central	0	yes	17.848	0.000	EPSD	ICGC	16.704	Loss
AGC_PKC_PKCa_PRKCA_ST	Q8WZ42	TTN	P17252	PRKCA	S17981	R17983L	17983	Missense	proximal	2	no	18.580	13.593	EPSD	ICGC;COSMIC	16.704	Loss
AGC_PKC_PKCa_PRKCA_ST	Q8WZ42	TTN	P17252	PRKCA	S17981	L17974M	17974	Missense	distal	-7	no	18.580	18.588	EPSD	ICGC;COSMIC	16.704	Up-regulation
AGC_PKC_PKCa_PRKCA_ST	Q8WZ42	TTN	P17252	PRKCA	S17981	K17976N	17976	Missense	distal	-5	no	18.580	18.237	EPSD	ICGC;COSMIC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	Q8WZ42	TTN	P17252	PRKCA	S17981	V17987G	17987	Missense	distal	6	no	18.580	18.591	EPSD	ICGC;COSMIC	16.704	Up-regulation
AGC_PKC_PKCa_PRKCA_ST	Q8WZ42	TTN	P17252	PRKCA	S17981	S17981F	17981	Missense	central	0	yes	18.580	0.000	EPSD	ICGC	16.704	Loss
AGC_PKC_PKCa_PRKCA_ST	Q8WZ42	TTN	P17252	PRKCA	S17981	S17981P	17981	Missense	central	0	yes	18.580	0.000	EPSD	ICGC;COSMIC	16.704	Loss
AGC_PKC_PKCa_PRKCA_ST	Q8WZ42	TTN	P17252	PRKCA	T18256	E18259K	18259	Missense	distal	3	no	16.378	16.993	EPSD	ICGC;COSMIC	16.704	Gain
AGC_PKC_PKCa_PRKCA_ST	Q8WZ42	TTN	P17252	PRKCA	T18505	E18507K	18507	Missense	proximal	2	no	13.696	18.975	EPSD	ICGC;COSMIC	16.704	Gain
AGC_PKC_PKCa_PRKCA_ST	Q8WZ42	TTN	P17252	PRKCA	S18583	V18580G	18580	Missense	distal	-3	no	16.676	17.104	EPSD	ICGC;COSMIC	16.704	Gain
AGC_PKC_PKCa_PRKCA_ST	Q8WZ42	TTN	P17252	PRKCA	S18585	V18580G	18580	Missense	distal	-5	no	17.209	17.483	EPSD	ICGC;COSMIC	16.704	Up-regulation
AGC_PKC_PKCa_PRKCA_ST	Q8WZ42	TTN	P17252	PRKCA	S18585	S18586I	18586	Missense	proximal	1	no	17.209	18.872	EPSD	ICGC;COSMIC	16.704	Up-regulation
AGC_PKC_PKCa_PRKCA_ST	Q8WZ42	TTN	P17252	PRKCA	S18909	Y18906F	18906	Missense	distal	-3	no	15.086	17.026	EPSD	ICGC;COSMIC	16.704	Gain
AGC_PKC_PKCa_PRKCA_ST	Q8WZ42	TTN	P17252	PRKCA	S19081	E19084K	19084	Missense	distal	3	no	20.524	21.140	EPSD	ICGC;COSMIC	16.704	Up-regulation
AGC_PKC_PKCa_PRKCA_ST	Q8WZ42	TTN	P17252	PRKCA	S19081	T19085S	19085	Missense	distal	4	no	20.524	20.955	EPSD	ICGC;COSMIC	16.704	Up-regulation
AGC_PKC_PKCa_PRKCA_ST	Q8WZ42	TTN	P17252	PRKCA	S19081	H19078R	19078	Missense	distal	-3	no	20.524	24.381	EPSD	ICGC;COSMIC	16.704	Up-regulation
AGC_PKC_PKCa_PRKCA_ST	Q8WZ42	TTN	P17252	PRKCA	S19174	A19168T	19168	Missense	distal	-6	no	17.207	17.119	EPSD	ICGC;COSMIC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	Q8WZ42	TTN	P17252	PRKCA	S19174	R19173I	19173	Missense	proximal	-1	no	17.207	15.537	EPSD	ICGC;COSMIC	16.704	Loss
AGC_PKC_PKCa_PRKCA_ST	Q8WZ42	TTN	P17252	PRKCA	S19174	P19175S	19175	Missense	proximal	1	no	17.207	16.808	EPSD	ICGC;COSMIC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	Q8WZ42	TTN	P17252	PRKCA	S19174	D19180H	19180	Missense	distal	6	no	17.207	17.219	EPSD	ICGC;COSMIC	16.704	Up-regulation
AGC_PKC_PKCa_PRKCA_ST	Q8WZ42	TTN	P17252	PRKCA	S19174	D19167E	19167	Missense	distal	-7	no	17.207	17.204	EPSD	ICGC;COSMIC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	Q8WZ42	TTN	P17252	PRKCA	S19174	R19173T	19173	Missense	proximal	-1	no	17.207	16.442	EPSD	ICGC;COSMIC	16.704	Loss
AGC_PKC_PKCa_PRKCA_ST	Q8WZ42	TTN	P17252	PRKCA	S19174	D19170Y	19170	Missense	distal	-4	no	17.207	17.692	EPSD	ICGC;COSMIC	16.704	Up-regulation
AGC_PKC_PKCa_PRKCA_ST	Q8WZ42	TTN	P17252	PRKCA	S19353	S19353F	19353	Missense	central	0	yes	16.837	0.000	EPSD	ICGC;COSMIC	16.704	Loss
AGC_PKC_PKCa_PRKCA_ST	Q8WZ42	TTN	P17252	PRKCA	S19353	F19358L	19358	Missense	distal	5	no	16.837	16.613	EPSD	ICGC;COSMIC	16.704	Loss
AGC_PKC_PKCa_PRKCA_ST	Q8WZ42	TTN	P17252	PRKCA	S19353	D19349A	19349	Missense	distal	-4	no	16.837	17.603	EPSD	ICGC;COSMIC	16.704	Up-regulation
AGC_PKC_PKCa_PRKCA_ST	Q8WZ42	TTN	P17252	PRKCA	S19353	S19353P	19353	Missense	central	0	yes	16.837	0.000	EPSD	ICGC;COSMIC	16.704	Loss
AGC_PKC_PKCa_PRKCA_ST	Q8WZ42	TTN	P17252	PRKCA	S19353	G19350A	19350	Missense	distal	-3	no	16.837	15.650	EPSD	ICGC;COSMIC	16.704	Loss
AGC_PKC_PKCa_PRKCA_ST	Q8WZ42	TTN	P17252	PRKCA	S19353	G19350C	19350	Missense	distal	-3	no	16.837	17.360	EPSD	ICGC;COSMIC	16.704	Up-regulation
AGC_PKC_PKCa_PRKCA_ST	Q8WZ42	TTN	P17252	PRKCA	S19366	E19363K	19363	Missense	distal	-3	no	16.282	19.194	EPSD	ICGC;COSMIC	16.704	Gain
AGC_PKC_PKCa_PRKCA_ST	Q8WZ42	TTN	P17252	PRKCA	S19604	T19606K	19606	Missense	proximal	2	no	12.605	16.993	EPSD	ICGC	16.704	Gain
AGC_PKC_PKCa_PRKCA_ST	Q8WZ42	TTN	P17252	PRKCA	S19763	T19762I	19762	Missense	proximal	-1	no	18.953	18.048	EPSD	ICGC;COSMIC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	Q8WZ42	TTN	P17252	PRKCA	S19763	I19757T	19757	Missense	distal	-6	no	18.953	18.924	EPSD	ICGC;COSMIC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	Q8WZ42	TTN	P17252	PRKCA	S19763	E19767Q	19767	Missense	distal	4	no	18.953	19.103	EPSD	ICGC;COSMIC	16.704	Up-regulation
AGC_PKC_PKCa_PRKCA_ST	Q8WZ42	TTN	P17252	PRKCA	T19908	E19901D	19901	Missense	distal	-7	no	16.836	16.839	EPSD	ICGC;COSMIC	16.704	Up-regulation
AGC_PKC_PKCa_PRKCA_ST	Q8WZ42	TTN	P17252	PRKCA	T19908	T19908N	19908	Missense	central	0	yes	16.836	0.000	EPSD	ICGC;COSMIC	16.704	Loss
AGC_PKC_PKCa_PRKCA_ST	Q8WZ42	TTN	P17252	PRKCA	T20168	C20166W	20166	Missense	proximal	-2	no	17.399	17.102	EPSD	ICGC;COSMIC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	Q8WZ42	TTN	P17252	PRKCA	T20168	R20165W	20165	Missense	distal	-3	no	17.399	15.045	EPSD	ICGC;COSMIC	16.704	Loss
AGC_PKC_PKCa_PRKCA_ST	Q8WZ42	TTN	P17252	PRKCA	T20168	H20171Q	20171	Missense	distal	3	no	17.399	15.658	EPSD	ICGC	16.704	Loss
AGC_PKC_PKCa_PRKCA_ST	Q8WZ42	TTN	P17252	PRKCA	T20168	P20174S	20174	Missense	distal	6	no	17.399	17.366	EPSD	ICGC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	Q8WZ42	TTN	P17252	PRKCA	S20255	P20250A	20250	Missense	distal	-5	no	18.384	18.005	EPSD	ICGC;COSMIC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	Q8WZ42	TTN	P17252	PRKCA	S20255	D20259G	20259	Missense	distal	4	no	18.384	18.379	EPSD	ICGC;COSMIC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	Q8WZ42	TTN	P17252	PRKCA	S20255	K20257E	20257	Missense	proximal	2	no	18.384	13.104	EPSD	ICGC;COSMIC	16.704	Loss
AGC_PKC_PKCa_PRKCA_ST	Q8WZ42	TTN	P17252	PRKCA	S20284	N20286K	20286	Missense	proximal	2	no	14.197	19.146	EPSD	ICGC	16.704	Gain
AGC_PKC_PKCa_PRKCA_ST	Q8WZ42	TTN	P17252	PRKCA	T20307	S20303C	20303	Missense	distal	-4	no	17.676	16.526	EPSD	ICGC;COSMIC	16.704	Loss
AGC_PKC_PKCa_PRKCA_ST	Q8WZ42	TTN	P17252	PRKCA	T20307	L20310F	20310	Missense	distal	3	no	17.676	18.010	EPSD	ICGC;COSMIC	16.704	Up-regulation
AGC_PKC_PKCa_PRKCA_ST	Q8WZ42	TTN	P17252	PRKCA	S20321	P20316R	20316	Missense	distal	-5	no	17.902	18.003	EPSD	ICGC;COSMIC	16.704	Up-regulation
AGC_PKC_PKCa_PRKCA_ST	Q8WZ42	TTN	P17252	PRKCA	S20321	P20318H	20318	Missense	distal	-3	no	17.902	17.894	EPSD	ICGC;COSMIC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	Q8WZ42	TTN	P17252	PRKCA	S20321	P20316L	20316	Missense	distal	-5	no	17.902	17.876	EPSD	ICGC;COSMIC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	Q8WZ42	TTN	P17252	PRKCA	S20329	R20331P	20331	Missense	proximal	2	no	19.405	14.203	EPSD	ICGC;COSMIC	16.704	Loss
AGC_PKC_PKCa_PRKCA_ST	Q8WZ42	TTN	P17252	PRKCA	S20329	A20332D	20332	Missense	distal	3	no	19.405	19.278	EPSD	ICGC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	Q8WZ42	TTN	P17252	PRKCA	S20329	R20331C	20331	Missense	proximal	2	no	19.405	15.055	EPSD	ICGC	16.704	Loss
AGC_PKC_PKCa_PRKCA_ST	Q8WZ42	TTN	P17252	PRKCA	T20762	T20764K	20764	Missense	proximal	2	no	14.858	19.247	EPSD	ICGC	16.704	Gain
AGC_PKC_PKCa_PRKCA_ST	Q8WZ42	TTN	P17252	PRKCA	S20864	Q20857K	20857	Missense	distal	-7	no	17.175	17.179	EPSD	ICGC	16.704	Up-regulation
AGC_PKC_PKCa_PRKCA_ST	Q8WZ42	TTN	P17252	PRKCA	S20864	D20871Y	20871	Missense	distal	7	no	17.175	17.167	EPSD	ICGC;COSMIC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	Q8WZ42	TTN	P17252	PRKCA	S20864	S20864G	20864	Missense	central	0	yes	17.175	0.000	EPSD	ICGC;COSMIC	16.704	Loss
AGC_PKC_PKCa_PRKCA_ST	Q8WZ42	TTN	P17252	PRKCA	S20864	S20868P	20868	Missense	distal	4	no	17.175	16.975	EPSD	ICGC;COSMIC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	Q8WZ42	TTN	P17252	PRKCA	S20864	D20871N	20871	Missense	distal	7	no	17.175	17.149	EPSD	ICGC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	Q8WZ42	TTN	P17252	PRKCA	S20864	R20858Q	20858	Missense	distal	-6	no	17.175	17.032	EPSD	ICGC;COSMIC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	Q8WZ42	TTN	P17252	PRKCA	S20864	K20870R	20870	Missense	distal	6	no	17.175	17.188	EPSD	ICGC;COSMIC	16.704	Up-regulation
AGC_PKC_PKCa_PRKCA_ST	Q8WZ42	TTN	P17252	PRKCA	S20868	K20870R	20870	Missense	proximal	2	no	16.415	16.837	EPSD	ICGC;COSMIC	16.704	Gain
AGC_PKC_PKCa_PRKCA_ST	Q8WZ42	TTN	P17252	PRKCA	T20879	E20885D	20885	Missense	distal	6	no	17.775	17.792	EPSD	ICGC;COSMIC	16.704	Up-regulation
AGC_PKC_PKCa_PRKCA_ST	Q8WZ42	TTN	P17252	PRKCA	T20879	E20877K	20877	Missense	proximal	-2	no	17.775	20.274	EPSD	ICGC;COSMIC	16.704	Up-regulation
AGC_PKC_PKCa_PRKCA_ST	Q8WZ42	TTN	P17252	PRKCA	T20879	G20875E	20875	Missense	distal	-4	no	17.775	17.181	EPSD	ICGC;COSMIC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	Q8WZ42	TTN	P17252	PRKCA	T20879	E20877V	20877	Missense	proximal	-2	no	17.775	19.060	EPSD	ICGC;COSMIC	16.704	Up-regulation
AGC_PKC_PKCa_PRKCA_ST	Q8WZ42	TTN	P17252	PRKCA	T21061	S21055L	21055	Missense	distal	-6	no	18.302	18.237	EPSD	ICGC;COSMIC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	Q8WZ42	TTN	P17252	PRKCA	T21061	Q21058R	21058	Missense	distal	-3	no	18.302	21.160	EPSD	ICGC;COSMIC	16.704	Up-regulation
AGC_PKC_PKCa_PRKCA_ST	Q8WZ42	TTN	P17252	PRKCA	T21074	M21071I	21071	Missense	distal	-3	no	16.819	15.303	EPSD	ICGC;COSMIC	16.704	Loss
AGC_PKC_PKCa_PRKCA_ST	Q8WZ42	TTN	P17252	PRKCA	T21074	G21070S	21070	Missense	distal	-4	no	16.819	16.727	EPSD	ICGC;COSMIC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	Q8WZ42	TTN	P17252	PRKCA	T21074	E21072K	21072	Missense	proximal	-2	no	16.819	19.317	EPSD	ICGC;COSMIC	16.704	Up-regulation
AGC_PKC_PKCa_PRKCA_ST	Q8WZ42	TTN	P17252	PRKCA	T21074	A21079V	21079	Missense	distal	5	no	16.819	16.435	EPSD	ICGC;COSMIC	16.704	Loss
AGC_PKC_PKCa_PRKCA_ST	Q8WZ42	TTN	P17252	PRKCA	T21074	E21080K	21080	Missense	distal	6	no	16.819	16.913	EPSD	ICGC;COSMIC	16.704	Up-regulation
AGC_PKC_PKCa_PRKCA_ST	Q8WZ42	TTN	P17252	PRKCA	S21078	E21080K	21080	Missense	proximal	2	no	14.117	19.396	EPSD	ICGC;COSMIC	16.704	Gain
AGC_PKC_PKCa_PRKCA_ST	Q8WZ42	TTN	P17252	PRKCA	S21339	P21336Q	21336	Missense	distal	-3	no	16.091	17.082	EPSD	ICGC	16.704	Gain
AGC_PKC_PKCa_PRKCA_ST	Q8WZ42	TTN	P17252	PRKCA	T21769	G21770S	21770	Missense	proximal	1	no	17.390	17.169	EPSD	ICGC;COSMIC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	Q8WZ42	TTN	P17252	PRKCA	T21769	T21775N	21775	Missense	distal	6	no	17.390	17.336	EPSD	ICGC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	Q8WZ42	TTN	P17252	PRKCA	T21769	V21773A	21773	Missense	distal	4	no	17.390	18.728	EPSD	ICGC;COSMIC	16.704	Up-regulation
AGC_PKC_PKCa_PRKCA_ST	Q8WZ42	TTN	P17252	PRKCA	T21837	R21834H	21834	Missense	distal	-3	no	16.917	13.061	EPSD	ICGC;COSMIC	16.704	Loss
AGC_PKC_PKCa_PRKCA_ST	Q8WZ42	TTN	P17252	PRKCA	T21837	S21842F	21842	Missense	distal	5	no	16.917	16.951	EPSD	ICGC;COSMIC	16.704	Up-regulation
AGC_PKC_PKCa_PRKCA_ST	Q8WZ42	TTN	P17252	PRKCA	T21837	S21842Y	21842	Missense	distal	5	no	16.917	16.944	EPSD	ICGC	16.704	Up-regulation
AGC_PKC_PKCa_PRKCA_ST	Q8WZ42	TTN	P17252	PRKCA	T21837	E21835G	21835	Missense	proximal	-2	no	16.917	18.171	EPSD	ICGC	16.704	Up-regulation
AGC_PKC_PKCa_PRKCA_ST	Q8WZ42	TTN	P17252	PRKCA	T21837	K21839T	21839	Missense	proximal	2	no	16.917	12.528	EPSD	ICGC	16.704	Loss
AGC_PKC_PKCa_PRKCA_ST	Q8WZ42	TTN	P17252	PRKCA	T21837	R21838Q	21838	Missense	proximal	1	no	16.917	16.800	EPSD	ICGC;COSMIC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	Q8WZ42	TTN	P17252	PRKCA	T21837	S21840Y	21840	Missense	distal	3	no	16.917	16.040	EPSD	ICGC;COSMIC	16.704	Loss
AGC_PKC_PKCa_PRKCA_ST	Q8WZ42	TTN	P17252	PRKCA	T21837	E21832K	21832	Missense	distal	-5	no	16.917	17.211	EPSD	ICGC;COSMIC	16.704	Up-regulation
AGC_PKC_PKCa_PRKCA_ST	Q8WZ42	TTN	P17252	PRKCA	T21837	R21838W	21838	Missense	proximal	1	no	16.917	16.193	EPSD	ICGC;COSMIC	16.704	Loss
AGC_PKC_PKCa_PRKCA_ST	Q8WZ42	TTN	P17252	PRKCA	S21840	R21834H	21834	Missense	distal	-6	no	17.035	16.967	EPSD	ICGC;COSMIC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	Q8WZ42	TTN	P17252	PRKCA	S21840	S21842F	21842	Missense	proximal	2	no	17.035	17.352	EPSD	ICGC;COSMIC	16.704	Up-regulation
AGC_PKC_PKCa_PRKCA_ST	Q8WZ42	TTN	P17252	PRKCA	S21840	S21842Y	21842	Missense	proximal	2	no	17.035	17.159	EPSD	ICGC	16.704	Up-regulation
AGC_PKC_PKCa_PRKCA_ST	Q8WZ42	TTN	P17252	PRKCA	S21840	E21835G	21835	Missense	distal	-5	no	17.035	17.052	EPSD	ICGC	16.704	Up-regulation
AGC_PKC_PKCa_PRKCA_ST	Q8WZ42	TTN	P17252	PRKCA	S21840	K21839T	21839	Missense	proximal	-1	no	17.035	16.212	EPSD	ICGC	16.704	Loss
AGC_PKC_PKCa_PRKCA_ST	Q8WZ42	TTN	P17252	PRKCA	S21840	R21838Q	21838	Missense	proximal	-2	no	17.035	15.276	EPSD	ICGC;COSMIC	16.704	Loss
AGC_PKC_PKCa_PRKCA_ST	Q8WZ42	TTN	P17252	PRKCA	S21840	S21840Y	21840	Missense	central	0	yes	17.035	0.000	EPSD	ICGC;COSMIC	16.704	Loss
AGC_PKC_PKCa_PRKCA_ST	Q8WZ42	TTN	P17252	PRKCA	S21840	R21838W	21838	Missense	proximal	-2	no	17.035	15.037	EPSD	ICGC;COSMIC	16.704	Loss
AGC_PKC_PKCa_PRKCA_ST	Q8WZ42	TTN	P17252	PRKCA	S21935	I21928N	21928	Missense	distal	-7	no	17.630	17.635	EPSD	ICGC;COSMIC	16.704	Up-regulation
AGC_PKC_PKCa_PRKCA_ST	Q8WZ42	TTN	P17252	PRKCA	S21935	G21934S	21934	Missense	proximal	-1	no	17.630	17.382	EPSD	ICGC;COSMIC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	Q8WZ42	TTN	P17252	PRKCA	S21935	T21942P	21942	Missense	distal	7	no	17.630	17.660	EPSD	ICGC;COSMIC	16.704	Up-regulation
AGC_PKC_PKCa_PRKCA_ST	Q8WZ42	TTN	P17252	PRKCA	S22272	P22274T	22274	Missense	proximal	2	no	17.084	17.477	EPSD	ICGC;COSMIC	16.704	Up-regulation
AGC_PKC_PKCa_PRKCA_ST	Q8WZ42	TTN	P17252	PRKCA	S22272	M22278I	22278	Missense	distal	6	no	17.084	17.051	EPSD	ICGC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	Q8WZ42	TTN	P17252	PRKCA	S22456	A22463V	22463	Missense	distal	7	no	17.421	17.366	EPSD	ICGC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	Q8WZ42	TTN	P17252	PRKCA	S22456	T22460N	22460	Missense	distal	4	no	17.421	17.142	EPSD	ICGC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	Q8WZ42	TTN	P17252	PRKCA	S22456	A22458D	22458	Missense	proximal	2	no	17.421	16.840	EPSD	ICGC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	Q8WZ42	TTN	P17252	PRKCA	S22456	G22457D	22457	Missense	proximal	1	no	17.421	16.775	EPSD	ICGC;COSMIC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	Q8WZ42	TTN	P17252	PRKCA	S22456	S22451L	22451	Missense	distal	-5	no	17.421	17.720	EPSD	ICGC;COSMIC	16.704	Up-regulation
AGC_PKC_PKCa_PRKCA_ST	Q8WZ42	TTN	P17252	PRKCA	S22456	D22455N	22455	Missense	proximal	-1	no	17.421	17.758	EPSD	ICGC;COSMIC	16.704	Up-regulation
AGC_PKC_PKCa_PRKCA_ST	Q8WZ42	TTN	P17252	PRKCA	S22456	R22454M	22454	Missense	proximal	-2	no	17.421	15.440	EPSD	ICGC;COSMIC	16.704	Loss
AGC_PKC_PKCa_PRKCA_ST	Q8WZ42	TTN	P17252	PRKCA	S22853	G22846A	22846	Missense	distal	-7	no	18.207	18.213	EPSD	ICGC;COSMIC	16.704	Up-regulation
AGC_PKC_PKCa_PRKCA_ST	Q8WZ42	TTN	P17252	PRKCA	S22853	S22853R	22853	Missense	central	0	yes	18.207	0.000	EPSD	ICGC;COSMIC	16.704	Loss
AGC_PKC_PKCa_PRKCA_ST	Q8WZ42	TTN	P17252	PRKCA	S22969	R22975Q	22975	Missense	distal	6	no	17.239	17.116	EPSD	ICGC;COSMIC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	Q8WZ42	TTN	P17252	PRKCA	S22969	A22967S	22967	Missense	proximal	-2	no	17.239	17.022	EPSD	ICGC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	Q8WZ42	TTN	P17252	PRKCA	S22969	P22976H	22976	Missense	distal	7	no	17.239	17.177	EPSD	ICGC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	Q8WZ42	TTN	P17252	PRKCA	S22969	L22962M	22962	Missense	distal	-7	no	17.239	17.247	EPSD	ICGC	16.704	Up-regulation
AGC_PKC_PKCa_PRKCA_ST	Q8WZ42	TTN	P17252	PRKCA	S22969	P22963H	22963	Missense	distal	-6	no	17.239	17.276	EPSD	ICGC;COSMIC	16.704	Up-regulation
AGC_PKC_PKCa_PRKCA_ST	Q8WZ42	TTN	P17252	PRKCA	S22969	A22967T	22967	Missense	proximal	-2	no	17.239	17.430	EPSD	ICGC;COSMIC	16.704	Up-regulation
AGC_PKC_PKCa_PRKCA_ST	Q8WZ42	TTN	P17252	PRKCA	S22969	E22968D	22968	Missense	proximal	-1	no	17.239	16.725	EPSD	ICGC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	Q8WZ42	TTN	P17252	PRKCA	S23063	D23070Y	23070	Missense	distal	7	no	18.677	18.668	EPSD	ICGC;COSMIC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	Q8WZ42	TTN	P17252	PRKCA	S23063	R23060T	23060	Missense	distal	-3	no	18.677	14.513	EPSD	ICGC;COSMIC	16.704	Loss
AGC_PKC_PKCa_PRKCA_ST	Q8WZ42	TTN	P17252	PRKCA	S23063	S23057N	23057	Missense	distal	-6	no	18.677	18.619	EPSD	ICGC;COSMIC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	Q8WZ42	TTN	P17252	PRKCA	S23063	S23057G	23057	Missense	distal	-6	no	18.677	18.643	EPSD	ICGC;COSMIC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	Q8WZ42	TTN	P17252	PRKCA	S23063	K23069N	23069	Missense	distal	6	no	18.677	18.515	EPSD	ICGC;COSMIC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	Q8WZ42	TTN	P17252	PRKCA	S23063	A23068T	23068	Missense	distal	5	no	18.677	18.398	EPSD	ICGC;COSMIC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	Q8WZ42	TTN	P17252	PRKCA	T23118	T23119A	23119	Missense	proximal	1	no	16.353	16.825	EPSD	ICGC	16.704	Gain
AGC_PKC_PKCa_PRKCA_ST	Q8WZ42	TTN	P17252	PRKCA	T23133	T23133K	23133	Missense	central	0	yes	16.803	0.000	EPSD	ICGC;COSMIC	16.704	Loss
AGC_PKC_PKCa_PRKCA_ST	Q8WZ42	TTN	P17252	PRKCA	T23133	R23139L	23139	Missense	distal	6	no	16.803	16.720	EPSD	ICGC;COSMIC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	Q8WZ42	TTN	P17252	PRKCA	T23133	A23137D	23137	Missense	distal	4	no	16.803	16.434	EPSD	ICGC	16.704	Loss
AGC_PKC_PKCa_PRKCA_ST	Q8WZ42	TTN	P17252	PRKCA	T23133	A23137T	23137	Missense	distal	4	no	16.803	16.355	EPSD	ICGC;COSMIC	16.704	Loss
AGC_PKC_PKCa_PRKCA_ST	Q8WZ42	TTN	P17252	PRKCA	T23133	R23139Q	23139	Missense	distal	6	no	16.803	16.680	EPSD	ICGC;COSMIC	16.704	Loss
AGC_PKC_PKCa_PRKCA_ST	Q8WZ42	TTN	P17252	PRKCA	T23133	E23127D	23127	Missense	distal	-6	no	16.803	16.719	EPSD	ICGC;COSMIC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	Q8WZ42	TTN	P17252	PRKCA	T23226	C23230F	23230	Missense	distal	4	no	17.741	18.534	EPSD	ICGC;COSMIC	16.704	Up-regulation
AGC_PKC_PKCa_PRKCA_ST	Q8WZ42	TTN	P17252	PRKCA	T23226	A23220T	23220	Missense	distal	-6	no	17.741	17.652	EPSD	ICGC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	Q8WZ42	TTN	P17252	PRKCA	T23226	K23228N	23228	Missense	proximal	2	no	17.741	12.792	EPSD	ICGC	16.704	Loss
AGC_PKC_PKCa_PRKCA_ST	Q8WZ42	TTN	P17252	PRKCA	T23252	G23249R	23249	Missense	distal	-3	no	14.168	17.430	EPSD	ICGC;COSMIC	16.704	Gain
AGC_PKC_PKCa_PRKCA_ST	Q8WZ42	TTN	P17252	PRKCA	S23279	R23281T	23281	Missense	proximal	2	no	17.437	12.627	EPSD	ICGC;COSMIC	16.704	Loss
AGC_PKC_PKCa_PRKCA_ST	Q8WZ42	TTN	P17252	PRKCA	S23279	V23275L	23275	Missense	distal	-4	no	17.437	17.478	EPSD	ICGC;COSMIC	16.704	Up-regulation
AGC_PKC_PKCa_PRKCA_ST	Q8WZ42	TTN	P17252	PRKCA	S23279	D23282E	23282	Missense	distal	3	no	17.437	17.924	EPSD	ICGC;COSMIC	16.704	Up-regulation
AGC_PKC_PKCa_PRKCA_ST	Q8WZ42	TTN	P17252	PRKCA	S24018	K24016R	24016	Missense	proximal	-2	no	15.433	17.061	EPSD	ICGC	16.704	Gain
AGC_PKC_PKCa_PRKCA_ST	Q8WZ42	TTN	P17252	PRKCA	S24112	A24108V	24108	Missense	distal	-4	no	17.365	16.806	EPSD	ICGC;COSMIC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	Q8WZ42	TTN	P17252	PRKCA	S24112	N24119S	24119	Missense	distal	7	no	17.365	17.388	EPSD	ICGC;COSMIC	16.704	Up-regulation
AGC_PKC_PKCa_PRKCA_ST	Q8WZ42	TTN	P17252	PRKCA	S24112	Q24114K	24114	Missense	proximal	2	no	17.365	20.777	EPSD	ICGC	16.704	Up-regulation
AGC_PKC_PKCa_PRKCA_ST	Q8WZ42	TTN	P17252	PRKCA	S24112	S24112F	24112	Missense	central	0	yes	17.365	0.000	EPSD	ICGC	16.704	Loss
AGC_PKC_PKCa_PRKCA_ST	Q8WZ42	TTN	P17252	PRKCA	S24112	E24106K	24106	Missense	distal	-6	no	17.365	17.432	EPSD	ICGC;COSMIC	16.704	Up-regulation
AGC_PKC_PKCa_PRKCA_ST	Q8WZ42	TTN	P17252	PRKCA	S24112	A24115V	24115	Missense	distal	3	no	17.365	17.108	EPSD	ICGC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	Q8WZ42	TTN	P17252	PRKCA	S24112	S24112Y	24112	Missense	central	0	yes	17.365	0.000	EPSD	ICGC;COSMIC	16.704	Loss
AGC_PKC_PKCa_PRKCA_ST	Q8WZ42	TTN	P17252	PRKCA	S24112	R24109Q	24109	Missense	distal	-3	no	17.365	14.507	EPSD	ICGC;COSMIC	16.704	Loss
AGC_PKC_PKCa_PRKCA_ST	Q8WZ42	TTN	P17252	PRKCA	S24167	Q24169K	24169	Missense	proximal	2	no	14.497	17.910	EPSD	ICGC	16.704	Gain
AGC_PKC_PKCa_PRKCA_ST	Q8WZ42	TTN	P17252	PRKCA	S24241	E24243K	24243	Missense	proximal	2	no	11.492	16.771	EPSD	ICGC;COSMIC	16.704	Gain
AGC_PKC_PKCa_PRKCA_ST	Q8WZ42	TTN	P17252	PRKCA	S24393	E24390K	24390	Missense	distal	-3	no	14.584	17.496	EPSD	ICGC;COSMIC	16.704	Gain
AGC_PKC_PKCa_PRKCA_ST	Q8WZ42	TTN	P17252	PRKCA	S24660	E24661K	24661	Missense	proximal	1	no	15.196	16.800	EPSD	ICGC;COSMIC;CCLE	16.704	Gain
AGC_PKC_PKCa_PRKCA_ST	Q8WZ42	TTN	P17252	PRKCA	T24688	E24684Q	24684	Missense	distal	-4	no	18.197	18.516	EPSD	ICGC;COSMIC	16.704	Up-regulation
AGC_PKC_PKCa_PRKCA_ST	Q8WZ42	TTN	P17252	PRKCA	T24688	R24690Q	24690	Missense	proximal	2	no	18.197	14.363	EPSD	ICGC;COSMIC;CCLE	16.704	Loss
AGC_PKC_PKCa_PRKCA_ST	Q8WZ42	TTN	P17252	PRKCA	T24688	R24686Q	24686	Missense	proximal	-2	no	18.197	16.438	EPSD	ICGC;COSMIC	16.704	Loss
AGC_PKC_PKCa_PRKCA_ST	Q8WZ42	TTN	P17252	PRKCA	T24688	E24687K	24687	Missense	proximal	-1	no	18.197	18.623	EPSD	ICGC;COSMIC	16.704	Up-regulation
AGC_PKC_PKCa_PRKCA_ST	Q8WZ42	TTN	P17252	PRKCA	S24689	E24687K	24687	Missense	proximal	-2	no	14.807	17.306	EPSD	ICGC;COSMIC	16.704	Gain
AGC_PKC_PKCa_PRKCA_ST	Q8WZ42	TTN	P17252	PRKCA	S24704	T24702S	24702	Missense	proximal	-2	no	18.327	17.919	EPSD	ICGC;COSMIC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	Q8WZ42	TTN	P17252	PRKCA	S24704	S24704Y	24704	Missense	central	0	yes	18.327	0.000	EPSD	ICGC;COSMIC	16.704	Loss
AGC_PKC_PKCa_PRKCA_ST	Q8WZ42	TTN	P17252	PRKCA	S24704	L24705M	24705	Missense	proximal	1	no	18.327	18.113	EPSD	ICGC;COSMIC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	Q8WZ42	TTN	P17252	PRKCA	S24704	S24704A	24704	Missense	central	0	yes	18.327	0.000	EPSD	ICGC;COSMIC	16.704	Loss
AGC_PKC_PKCa_PRKCA_ST	Q8WZ42	TTN	P17252	PRKCA	S24704	E24699K	24699	Missense	distal	-5	no	18.327	18.621	EPSD	ICGC;COSMIC	16.704	Up-regulation
AGC_PKC_PKCa_PRKCA_ST	Q8WZ42	TTN	P17252	PRKCA	S24704	S24704F	24704	Missense	central	0	yes	18.327	0.000	EPSD	ICGC;COSMIC	16.704	Loss
AGC_PKC_PKCa_PRKCA_ST	Q8WZ42	TTN	P17252	PRKCA	S24788	I24781T	24781	Missense	distal	-7	no	17.209	17.216	EPSD	ICGC;COSMIC	16.704	Up-regulation
AGC_PKC_PKCa_PRKCA_ST	Q8WZ42	TTN	P17252	PRKCA	S24788	D24786E	24786	Missense	proximal	-2	no	17.209	16.501	EPSD	ICGC;COSMIC	16.704	Loss
AGC_PKC_PKCa_PRKCA_ST	Q8WZ42	TTN	P17252	PRKCA	S24788	I24781N	24781	Missense	distal	-7	no	17.209	17.214	EPSD	ICGC;COSMIC	16.704	Up-regulation
AGC_PKC_PKCa_PRKCA_ST	Q8WZ42	TTN	P17252	PRKCA	S24788	D24786G	24786	Missense	proximal	-2	no	17.209	17.755	EPSD	ICGC;COSMIC	16.704	Up-regulation
AGC_PKC_PKCa_PRKCA_ST	Q8WZ42	TTN	P17252	PRKCA	T24801	R24804H	24804	Missense	distal	3	no	17.149	16.437	EPSD	ICGC;COSMIC	16.704	Loss
AGC_PKC_PKCa_PRKCA_ST	Q8WZ42	TTN	P17252	PRKCA	T24801	T24801A	24801	Missense	central	0	yes	17.149	0.000	EPSD	ICGC;COSMIC	16.704	Loss
AGC_PKC_PKCa_PRKCA_ST	Q8WZ42	TTN	P17252	PRKCA	T24801	L24805I	24805	Missense	distal	4	no	17.149	16.497	EPSD	ICGC;COSMIC	16.704	Loss
AGC_PKC_PKCa_PRKCA_ST	Q8WZ42	TTN	P17252	PRKCA	T24801	R24798H	24798	Missense	distal	-3	no	17.149	13.293	EPSD	ICGC;COSMIC;CCLE	16.704	Loss
AGC_PKC_PKCa_PRKCA_ST	Q8WZ42	TTN	P17252	PRKCA	T24801	R24798C	24798	Missense	distal	-3	no	17.149	14.410	EPSD	ICGC;COSMIC;CCLE	16.704	Loss
AGC_PKC_PKCa_PRKCA_ST	Q8WZ42	TTN	P17252	PRKCA	T24801	T24808I	24808	Missense	distal	7	no	17.149	16.990	EPSD	ICGC;COSMIC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	Q8WZ42	TTN	P17252	PRKCA	S24821	E24823K	24823	Missense	proximal	2	no	13.363	18.643	EPSD	ICGC	16.704	Gain
AGC_PKC_PKCa_PRKCA_ST	Q8WZ42	TTN	P17252	PRKCA	S25030	S25027R	25027	Missense	distal	-3	no	14.066	16.936	EPSD	ICGC	16.704	Gain
AGC_PKC_PKCa_PRKCA_ST	Q8WZ42	TTN	P17252	PRKCA	S25204	Q25206K	25206	Missense	proximal	2	no	14.423	17.835	EPSD	ICGC	16.704	Gain
AGC_PKC_PKCa_PRKCA_ST	Q8WZ42	TTN	P17252	PRKCA	S25383	T25385K	25385	Missense	proximal	2	no	12.868	17.257	EPSD	ICGC	16.704	Gain
AGC_PKC_PKCa_PRKCA_ST	Q8WZ42	TTN	P17252	PRKCA	S25442	D25446Y	25446	Missense	distal	4	no	16.953	16.908	EPSD	ICGC;COSMIC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	Q8WZ42	TTN	P17252	PRKCA	S25442	P25435R	25435	Missense	distal	-7	no	16.953	16.961	EPSD	ICGC;COSMIC	16.704	Up-regulation
AGC_PKC_PKCa_PRKCA_ST	Q8WZ42	TTN	P17252	PRKCA	S25442	P25435H	25435	Missense	distal	-7	no	16.953	16.954	EPSD	ICGC;COSMIC	16.704	Up-regulation
AGC_PKC_PKCa_PRKCA_ST	Q8WZ42	TTN	P17252	PRKCA	S25442	F25439S	25439	Missense	distal	-3	no	16.953	16.703	EPSD	ICGC;COSMIC	16.704	Loss
AGC_PKC_PKCa_PRKCA_ST	Q8WZ42	TTN	P17252	PRKCA	S25442	P25438S	25438	Missense	distal	-4	no	16.953	17.124	EPSD	ICGC;COSMIC	16.704	Up-regulation
AGC_PKC_PKCa_PRKCA_ST	Q8WZ42	TTN	P17252	PRKCA	T25624	D25627H	25627	Missense	distal	3	no	15.890	16.903	EPSD	ICGC;COSMIC	16.704	Gain
AGC_PKC_PKCa_PRKCA_ST	Q8WZ42	TTN	P17252	PRKCA	S25898	E25900K	25900	Missense	proximal	2	no	11.463	16.743	EPSD	ICGC;COSMIC	16.704	Gain
AGC_PKC_PKCa_PRKCA_ST	Q8WZ42	TTN	P17252	PRKCA	S26266	Q26262H	26262	Missense	distal	-4	no	17.213	17.016	EPSD	ICGC;COSMIC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	Q8WZ42	TTN	P17252	PRKCA	S26266	C26272Y	26272	Missense	distal	6	no	17.213	17.400	EPSD	ICGC;COSMIC	16.704	Up-regulation
AGC_PKC_PKCa_PRKCA_ST	Q8WZ42	TTN	P17252	PRKCA	S26266	C26272F	26272	Missense	distal	6	no	17.213	17.340	EPSD	ICGC;COSMIC	16.704	Up-regulation
AGC_PKC_PKCa_PRKCA_ST	Q8WZ42	TTN	P17252	PRKCA	S26266	E26267K	26267	Missense	proximal	1	no	17.213	18.817	EPSD	ICGC;COSMIC	16.704	Up-regulation
AGC_PKC_PKCa_PRKCA_ST	Q8WZ42	TTN	P17252	PRKCA	T26352	N26354K	26354	Missense	proximal	2	no	12.170	17.119	EPSD	ICGC;COSMIC	16.704	Gain
AGC_PKC_PKCa_PRKCA_ST	Q8WZ42	TTN	P17252	PRKCA	S26380	K26386R	26386	Missense	distal	6	no	17.875	17.888	EPSD	ICGC;COSMIC	16.704	Up-regulation
AGC_PKC_PKCa_PRKCA_ST	Q8WZ42	TTN	P17252	PRKCA	S26380	S26378T	26378	Missense	proximal	-2	no	17.875	18.284	EPSD	ICGC;COSMIC	16.704	Up-regulation
AGC_PKC_PKCa_PRKCA_ST	Q8WZ42	TTN	P17252	PRKCA	S26472	L26478P	26478	Missense	distal	6	no	16.863	16.907	EPSD	ICGC	16.704	Up-regulation
AGC_PKC_PKCa_PRKCA_ST	Q8WZ42	TTN	P17252	PRKCA	S26472	R26470K	26470	Missense	proximal	-2	no	16.863	15.236	EPSD	ICGC	16.704	Loss
AGC_PKC_PKCa_PRKCA_ST	Q8WZ42	TTN	P17252	PRKCA	S26472	R26477H	26477	Missense	distal	5	no	16.863	16.604	EPSD	ICGC;COSMIC	16.704	Loss
AGC_PKC_PKCa_PRKCA_ST	Q8WZ42	TTN	P17252	PRKCA	S26472	S26465P	26465	Missense	distal	-7	no	16.863	16.860	EPSD	ICGC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	Q8WZ42	TTN	P17252	PRKCA	S26472	V26468I	26468	Missense	distal	-4	no	16.863	16.893	EPSD	ICGC	16.704	Up-regulation
AGC_PKC_PKCa_PRKCA_ST	Q8WZ42	TTN	P17252	PRKCA	S26557	E26554K	26554	Missense	distal	-3	no	15.540	18.452	EPSD	ICGC;COSMIC	16.704	Gain
AGC_PKC_PKCa_PRKCA_ST	Q8WZ42	TTN	P17252	PRKCA	T26784	Q26786K	26786	Missense	proximal	2	no	15.171	18.584	EPSD	ICGC	16.704	Gain
AGC_PKC_PKCa_PRKCA_ST	Q8WZ42	TTN	P17252	PRKCA	S27015	P27017R	27017	Missense	proximal	2	no	14.187	19.390	EPSD	ICGC;COSMIC	16.704	Gain
AGC_PKC_PKCa_PRKCA_ST	Q8WZ42	TTN	P17252	PRKCA	S27063	R27065Q	27065	Missense	proximal	2	no	18.349	14.515	EPSD	ICGC;COSMIC	16.704	Loss
AGC_PKC_PKCa_PRKCA_ST	Q8WZ42	TTN	P17252	PRKCA	S27063	S27063N	27063	Missense	central	0	yes	18.349	0.000	EPSD	ICGC;COSMIC	16.704	Loss
AGC_PKC_PKCa_PRKCA_ST	Q8WZ42	TTN	P17252	PRKCA	S27063	T27067P	27067	Missense	distal	4	no	18.349	18.580	EPSD	ICGC;COSMIC	16.704	Up-regulation
AGC_PKC_PKCa_PRKCA_ST	Q8WZ42	TTN	P17252	PRKCA	S27063	W27057L	27057	Missense	distal	-6	no	18.349	18.495	EPSD	ICGC;COSMIC	16.704	Up-regulation
AGC_PKC_PKCa_PRKCA_ST	Q8WZ42	TTN	P17252	PRKCA	S27262	R27260S	27260	Missense	proximal	-2	no	17.720	14.418	EPSD	ICGC	16.704	Loss
AGC_PKC_PKCa_PRKCA_ST	Q8WZ42	TTN	P17252	PRKCA	S27262	S27262A	27262	Missense	central	0	yes	17.720	0.000	EPSD	ICGC;COSMIC	16.704	Loss
AGC_PKC_PKCa_PRKCA_ST	Q8WZ42	TTN	P17252	PRKCA	T27299	I27298L	27298	Missense	proximal	-1	no	16.665	17.529	EPSD	ICGC	16.704	Gain
AGC_PKC_PKCa_PRKCA_ST	Q8WZ42	TTN	P17252	PRKCA	T27299	G27295R	27295	Missense	distal	-4	no	16.665	16.767	EPSD	ICGC;COSMIC	16.704	Gain
AGC_PKC_PKCa_PRKCA_ST	Q8WZ42	TTN	P17252	PRKCA	S27640	W27643R	27643	Missense	distal	3	no	14.219	17.152	EPSD	ICGC;COSMIC	16.704	Gain
AGC_PKC_PKCa_PRKCA_ST	Q8WZ42	TTN	P17252	PRKCA	S27824	A27821V	27821	Missense	distal	-3	no	16.533	17.292	EPSD	ICGC;COSMIC	16.704	Gain
AGC_PKC_PKCa_PRKCA_ST	Q8WZ42	TTN	P17252	PRKCA	T28046	R28048H	28048	Missense	proximal	2	no	18.632	13.608	EPSD	ICGC;COSMIC	16.704	Loss
AGC_PKC_PKCa_PRKCA_ST	Q8WZ42	TTN	P17252	PRKCA	T28046	R28048S	28048	Missense	proximal	2	no	18.632	14.012	EPSD	ICGC	16.704	Loss
AGC_PKC_PKCa_PRKCA_ST	Q8WZ42	TTN	P17252	PRKCA	T28046	R28051T	28051	Missense	distal	5	no	18.632	18.315	EPSD	ICGC;COSMIC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	Q8WZ42	TTN	P17252	PRKCA	T28046	D28049E	28049	Missense	distal	3	no	18.632	19.118	EPSD	ICGC;COSMIC	16.704	Up-regulation
AGC_PKC_PKCa_PRKCA_ST	Q8WZ42	TTN	P17252	PRKCA	T28046	R28048C	28048	Missense	proximal	2	no	18.632	14.281	EPSD	ICGC;COSMIC	16.704	Loss
AGC_PKC_PKCa_PRKCA_ST	Q8WZ42	TTN	P17252	PRKCA	S28144	G28147R	28147	Missense	distal	3	no	16.478	17.118	EPSD	ICGC;COSMIC	16.704	Gain
AGC_PKC_PKCa_PRKCA_ST	Q8WZ42	TTN	P17252	PRKCA	S28286	P28293T	28293	Missense	distal	7	no	18.189	18.159	EPSD	ICGC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	Q8WZ42	TTN	P17252	PRKCA	S28286	S28282P	28282	Missense	distal	-4	no	18.189	18.017	EPSD	ICGC;COSMIC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	Q8WZ42	TTN	P17252	PRKCA	S28286	V28287I	28287	Missense	proximal	1	no	18.189	18.900	EPSD	ICGC;COSMIC	16.704	Up-regulation
AGC_PKC_PKCa_PRKCA_ST	Q8WZ42	TTN	P17252	PRKCA	S28340	R28337I	28337	Missense	distal	-3	no	18.217	13.730	EPSD	ICGC;COSMIC	16.704	Loss
AGC_PKC_PKCa_PRKCA_ST	Q8WZ42	TTN	P17252	PRKCA	S28340	V28342M	28342	Missense	proximal	2	no	18.217	18.783	EPSD	ICGC	16.704	Up-regulation
AGC_PKC_PKCa_PRKCA_ST	Q8WZ42	TTN	P17252	PRKCA	S28340	A28334G	28334	Missense	distal	-6	no	18.217	18.220	EPSD	ICGC;COSMIC	16.704	Up-regulation
AGC_PKC_PKCa_PRKCA_ST	Q8WZ42	TTN	P17252	PRKCA	S28340	A28334T	28334	Missense	distal	-6	no	18.217	18.128	EPSD	ICGC;COSMIC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	Q8WZ42	TTN	P17252	PRKCA	S28340	K28345T	28345	Missense	distal	5	no	18.217	17.756	EPSD	ICGC;COSMIC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	Q8WZ42	TTN	P17252	PRKCA	S28343	R28337I	28337	Missense	distal	-6	no	17.042	16.872	EPSD	ICGC;COSMIC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	Q8WZ42	TTN	P17252	PRKCA	S28343	V28342M	28342	Missense	proximal	-1	no	17.042	19.164	EPSD	ICGC	16.704	Up-regulation
AGC_PKC_PKCa_PRKCA_ST	Q8WZ42	TTN	P17252	PRKCA	S28343	K28345T	28345	Missense	proximal	2	no	17.042	12.653	EPSD	ICGC;COSMIC	16.704	Loss
AGC_PKC_PKCa_PRKCA_ST	Q8WZ42	TTN	P17252	PRKCA	S28397	R28394C	28394	Missense	distal	-3	no	20.692	17.953	EPSD	ICGC;COSMIC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	Q8WZ42	TTN	P17252	PRKCA	S28397	S28397L	28397	Missense	central	0	yes	20.692	0.000	EPSD	ICGC;COSMIC	16.704	Loss
AGC_PKC_PKCa_PRKCA_ST	Q8WZ42	TTN	P17252	PRKCA	S28397	R28394S	28394	Missense	distal	-3	no	20.692	17.822	EPSD	ICGC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	Q8WZ42	TTN	P17252	PRKCA	S28521	P28518R	28518	Missense	distal	-3	no	15.478	19.327	EPSD	ICGC;COSMIC	16.704	Gain
AGC_PKC_PKCa_PRKCA_ST	Q8WZ42	TTN	P17252	PRKCA	S28540	E28543K	28543	Missense	distal	3	no	16.943	17.559	EPSD	ICGC;COSMIC	16.704	Up-regulation
AGC_PKC_PKCa_PRKCA_ST	Q8WZ42	TTN	P17252	PRKCA	S28540	T28547I	28547	Missense	distal	7	no	16.943	16.783	EPSD	ICGC;COSMIC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	Q8WZ42	TTN	P17252	PRKCA	S28540	I28546T	28546	Missense	distal	6	no	16.943	16.929	EPSD	ICGC;COSMIC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	Q8WZ42	TTN	P17252	PRKCA	S28540	K28541I	28541	Missense	proximal	1	no	16.943	17.395	EPSD	ICGC;COSMIC	16.704	Up-regulation
AGC_PKC_PKCa_PRKCA_ST	Q8WZ42	TTN	P17252	PRKCA	S28540	R28538C	28538	Missense	proximal	-2	no	16.943	15.243	EPSD	ICGC;COSMIC;CCLE	16.704	Loss
AGC_PKC_PKCa_PRKCA_ST	Q8WZ42	TTN	P17252	PRKCA	S28549	E28543K	28543	Missense	distal	-6	no	18.929	18.997	EPSD	ICGC;COSMIC	16.704	Up-regulation
AGC_PKC_PKCa_PRKCA_ST	Q8WZ42	TTN	P17252	PRKCA	S28549	T28547I	28547	Missense	proximal	-2	no	18.929	18.235	EPSD	ICGC;COSMIC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	Q8WZ42	TTN	P17252	PRKCA	S28549	I28546T	28546	Missense	distal	-3	no	18.929	19.254	EPSD	ICGC;COSMIC	16.704	Up-regulation
AGC_PKC_PKCa_PRKCA_ST	Q8WZ42	TTN	P17252	PRKCA	S28627	E28625K	28625	Missense	proximal	-2	no	14.790	17.289	EPSD	ICGC;COSMIC	16.704	Gain
AGC_PKC_PKCa_PRKCA_ST	Q8WZ42	TTN	P17252	PRKCA	S28637	R28640I	28640	Missense	distal	3	no	17.529	14.980	EPSD	ICGC;COSMIC	16.704	Loss
AGC_PKC_PKCa_PRKCA_ST	Q8WZ42	TTN	P17252	PRKCA	S28739	S28739C	28739	Missense	central	0	yes	17.529	0.000	EPSD	ICGC	16.704	Loss
AGC_PKC_PKCa_PRKCA_ST	Q8WZ42	TTN	P17252	PRKCA	S28739	S28739F	28739	Missense	central	0	yes	17.529	0.000	EPSD	ICGC	16.704	Loss
AGC_PKC_PKCa_PRKCA_ST	Q8WZ42	TTN	P17252	PRKCA	S28739	N28734I	28734	Missense	distal	-5	no	17.529	17.313	EPSD	ICGC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	Q8WZ42	TTN	P17252	PRKCA	S28739	V28733I	28733	Missense	distal	-6	no	17.529	17.545	EPSD	ICGC;COSMIC	16.704	Up-regulation
AGC_PKC_PKCa_PRKCA_ST	Q8WZ42	TTN	P17252	PRKCA	S28902	G28900A	28900	Missense	proximal	-2	no	19.276	19.062	EPSD	ICGC;COSMIC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	Q8WZ42	TTN	P17252	PRKCA	S28966	A28960S	28960	Missense	distal	-6	no	18.220	18.257	EPSD	ICGC;COSMIC	16.704	Up-regulation
AGC_PKC_PKCa_PRKCA_ST	Q8WZ42	TTN	P17252	PRKCA	S29135	I29129M	29129	Missense	distal	-6	no	18.542	18.636	EPSD	ICGC;COSMIC	16.704	Up-regulation
AGC_PKC_PKCa_PRKCA_ST	Q8WZ42	TTN	P17252	PRKCA	S29135	K29131R	29131	Missense	distal	-4	no	18.542	18.506	EPSD	ICGC;COSMIC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	Q8WZ42	TTN	P17252	PRKCA	S29135	R29132Q	29132	Missense	distal	-3	no	18.542	15.684	EPSD	ICGC;COSMIC	16.704	Loss
AGC_PKC_PKCa_PRKCA_ST	Q8WZ42	TTN	P17252	PRKCA	S29135	P29133S	29133	Missense	proximal	-2	no	18.542	18.282	EPSD	ICGC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	Q8WZ42	TTN	P17252	PRKCA	T29272	A29275S	29275	Missense	distal	3	no	16.908	17.114	EPSD	ICGC;COSMIC	16.704	Up-regulation
AGC_PKC_PKCa_PRKCA_ST	Q8WZ42	TTN	P17252	PRKCA	T29272	A29275E	29275	Missense	distal	3	no	16.908	17.267	EPSD	ICGC	16.704	Up-regulation
AGC_PKC_PKCa_PRKCA_ST	Q8WZ42	TTN	P17252	PRKCA	T29272	D29277E	29277	Missense	distal	5	no	16.908	17.000	EPSD	ICGC;COSMIC	16.704	Up-regulation
AGC_PKC_PKCa_PRKCA_ST	Q8WZ42	TTN	P17252	PRKCA	S29301	R29303C	29303	Missense	proximal	2	no	17.050	12.699	EPSD	ICGC;COSMIC	16.704	Loss
AGC_PKC_PKCa_PRKCA_ST	Q8WZ42	TTN	P17252	PRKCA	S29301	H29294N	29294	Missense	distal	-7	no	17.050	17.047	EPSD	ICGC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	Q8WZ42	TTN	P17252	PRKCA	S29301	A29298T	29298	Missense	distal	-3	no	17.050	17.335	EPSD	ICGC;COSMIC	16.704	Up-regulation
AGC_PKC_PKCa_PRKCA_ST	Q8WZ42	TTN	P17252	PRKCA	S29301	I29306V	29306	Missense	distal	5	no	17.050	16.962	EPSD	ICGC;COSMIC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	Q8WZ42	TTN	P17252	PRKCA	S29301	R29303H	29303	Missense	proximal	2	no	17.050	12.026	EPSD	ICGC;COSMIC	16.704	Loss
AGC_PKC_PKCa_PRKCA_ST	Q8WZ42	TTN	P17252	PRKCA	S29421	R29419H	29419	Missense	proximal	-2	no	17.037	12.484	EPSD	ICGC;COSMIC	16.704	Loss
AGC_PKC_PKCa_PRKCA_ST	Q8WZ42	TTN	P17252	PRKCA	S29421	S29426N	29426	Missense	distal	5	no	17.037	16.817	EPSD	ICGC;COSMIC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	Q8WZ42	TTN	P17252	PRKCA	S29421	A29417S	29417	Missense	distal	-4	no	17.037	16.950	EPSD	ICGC;COSMIC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	Q8WZ42	TTN	P17252	PRKCA	S29421	R29420H	29420	Missense	proximal	-1	no	17.037	16.714	EPSD	ICGC;COSMIC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	Q8WZ42	TTN	P17252	PRKCA	S29421	R29420S	29420	Missense	proximal	-1	no	17.037	16.650	EPSD	ICGC;COSMIC	16.704	Loss
AGC_PKC_PKCa_PRKCA_ST	Q8WZ42	TTN	P17252	PRKCA	S29421	R29415Q	29415	Missense	distal	-6	no	17.037	16.894	EPSD	ICGC;COSMIC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	Q8WZ42	TTN	P17252	PRKCA	T29618	V29621E	29621	Missense	distal	3	no	16.111	16.726	EPSD	ICGC;COSMIC	16.704	Gain
AGC_PKC_PKCa_PRKCA_ST	Q8WZ42	TTN	P17252	PRKCA	S29637	D29636Y	29636	Missense	proximal	-1	no	19.038	19.084	EPSD	ICGC;COSMIC	16.704	Up-regulation
AGC_PKC_PKCa_PRKCA_ST	Q8WZ42	TTN	P17252	PRKCA	S29642	D29636Y	29636	Missense	distal	-6	no	17.761	17.792	EPSD	ICGC;COSMIC	16.704	Up-regulation
AGC_PKC_PKCa_PRKCA_ST	Q8WZ42	TTN	P17252	PRKCA	S29710	S29710P	29710	Missense	central	0	yes	16.860	0.000	EPSD	ICGC;COSMIC	16.704	Loss
AGC_PKC_PKCa_PRKCA_ST	Q8WZ42	TTN	P17252	PRKCA	S29710	R29708H	29708	Missense	proximal	-2	no	16.860	12.307	EPSD	ICGC;COSMIC	16.704	Loss
AGC_PKC_PKCa_PRKCA_ST	Q8WZ42	TTN	P17252	PRKCA	S29710	S29710L	29710	Missense	central	0	yes	16.860	0.000	EPSD	ICGC;COSMIC	16.704	Loss
AGC_PKC_PKCa_PRKCA_ST	Q8WZ42	TTN	P17252	PRKCA	S29721	Q29726E	29726	Missense	distal	5	no	19.457	19.196	EPSD	ICGC;COSMIC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	Q8WZ42	TTN	P17252	PRKCA	S29721	K29723E	29723	Missense	proximal	2	no	19.457	14.178	EPSD	ICGC;COSMIC	16.704	Loss
AGC_PKC_PKCa_PRKCA_ST	Q8WZ42	TTN	P17252	PRKCA	S29721	R29724H	29724	Missense	distal	3	no	19.457	18.745	EPSD	ICGC;COSMIC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	Q8WZ42	TTN	P17252	PRKCA	S29785	A29783V	29783	Missense	proximal	-2	no	19.319	19.563	EPSD	ICGC;COSMIC	16.704	Up-regulation
AGC_PKC_PKCa_PRKCA_ST	Q8WZ42	TTN	P17252	PRKCA	S29785	H29778R	29778	Missense	distal	-7	no	19.319	19.326	EPSD	ICGC;COSMIC	16.704	Up-regulation
AGC_PKC_PKCa_PRKCA_ST	Q8WZ42	TTN	P17252	PRKCA	S29785	R29787C	29787	Missense	proximal	2	no	19.319	14.969	EPSD	ICGC;COSMIC	16.704	Loss
AGC_PKC_PKCa_PRKCA_ST	Q8WZ42	TTN	P17252	PRKCA	S29785	V29779M	29779	Missense	distal	-6	no	19.319	19.430	EPSD	ICGC;COSMIC	16.704	Up-regulation
AGC_PKC_PKCa_PRKCA_ST	Q8WZ42	TTN	P17252	PRKCA	S29785	Y29792N	29792	Missense	distal	7	no	19.319	19.302	EPSD	ICGC;COSMIC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	Q8WZ42	TTN	P17252	PRKCA	S29785	E29789K	29789	Missense	distal	4	no	19.319	19.859	EPSD	ICGC;COSMIC	16.704	Up-regulation
AGC_PKC_PKCa_PRKCA_ST	Q8WZ42	TTN	P17252	PRKCA	S29785	R29787H	29787	Missense	proximal	2	no	19.319	14.296	EPSD	ICGC	16.704	Loss
AGC_PKC_PKCa_PRKCA_ST	Q8WZ42	TTN	P17252	PRKCA	S29785	Y29792C	29792	Missense	distal	7	no	19.319	19.148	EPSD	ICGC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	Q8WZ42	TTN	P17252	PRKCA	S29785	S29785Y	29785	Missense	central	0	yes	19.319	0.000	EPSD	ICGC;COSMIC;CCLE	16.704	Loss
AGC_PKC_PKCa_PRKCA_ST	Q8WZ42	TTN	P17252	PRKCA	T30026	K30020N	30020	Missense	distal	-6	no	17.346	17.223	EPSD	ICGC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	Q8WZ42	TTN	P17252	PRKCA	T30026	S30022Y	30022	Missense	distal	-4	no	17.346	17.153	EPSD	ICGC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	Q8WZ42	TTN	P17252	PRKCA	T30026	E30019K	30019	Missense	distal	-7	no	17.346	17.354	EPSD	ICGC;COSMIC	16.704	Up-regulation
AGC_PKC_PKCa_PRKCA_ST	Q8WZ42	TTN	P17252	PRKCA	T30075	S30077R	30077	Missense	proximal	2	no	13.724	18.344	EPSD	ICGC;COSMIC	16.704	Gain
AGC_PKC_PKCa_PRKCA_ST	Q8WZ42	TTN	P17252	PRKCA	T30384	A30387S	30387	Missense	distal	3	no	18.029	18.235	EPSD	ICGC;COSMIC	16.704	Up-regulation
AGC_PKC_PKCa_PRKCA_ST	Q8WZ42	TTN	P17252	PRKCA	T30384	R30386M	30386	Missense	proximal	2	no	18.029	13.581	EPSD	ICGC;COSMIC	16.704	Loss
AGC_PKC_PKCa_PRKCA_ST	Q8WZ42	TTN	P17252	PRKCA	T30384	T30382N	30382	Missense	proximal	-2	no	18.029	17.726	EPSD	ICGC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	Q8WZ42	TTN	P17252	PRKCA	T30384	A30387V	30387	Missense	distal	3	no	18.029	17.772	EPSD	ICGC;COSMIC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	Q8WZ42	TTN	P17252	PRKCA	T30384	A30387T	30387	Missense	distal	3	no	18.029	17.790	EPSD	ICGC;COSMIC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	Q8WZ42	TTN	P17252	PRKCA	S30390	A30387S	30387	Missense	distal	-3	no	15.268	16.847	EPSD	ICGC;COSMIC	16.704	Gain
AGC_PKC_PKCa_PRKCA_ST	Q8WZ42	TTN	P17252	PRKCA	S30450	A30455T	30455	Missense	distal	5	no	17.410	17.131	EPSD	ICGC;COSMIC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	Q8WZ42	TTN	P17252	PRKCA	S30450	N30448I	30448	Missense	proximal	-2	no	17.410	17.018	EPSD	ICGC;COSMIC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	Q8WZ42	TTN	P17252	PRKCA	S30450	G30451S	30451	Missense	proximal	1	no	17.410	17.189	EPSD	ICGC;COSMIC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	Q8WZ42	TTN	P17252	PRKCA	S30450	T30456A	30456	Missense	distal	6	no	17.410	17.488	EPSD	ICGC;COSMIC	16.704	Up-regulation
AGC_PKC_PKCa_PRKCA_ST	Q8WZ42	TTN	P17252	PRKCA	S30470	T30464A	30464	Missense	distal	-6	no	19.760	19.849	EPSD	ICGC;COSMIC	16.704	Up-regulation
AGC_PKC_PKCa_PRKCA_ST	Q8WZ42	TTN	P17252	PRKCA	S30470	E30475K	30475	Missense	distal	5	no	19.760	20.174	EPSD	ICGC	16.704	Up-regulation
AGC_PKC_PKCa_PRKCA_ST	Q8WZ42	TTN	P17252	PRKCA	S30470	D30463Y	30463	Missense	distal	-7	no	19.760	19.764	EPSD	ICGC;COSMIC	16.704	Up-regulation
AGC_PKC_PKCa_PRKCA_ST	Q8WZ42	TTN	P17252	PRKCA	S30709	V30712I	30712	Missense	distal	3	no	19.787	19.092	EPSD	ICGC;COSMIC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	Q8WZ42	TTN	P17252	PRKCA	S30709	R30711L	30711	Missense	proximal	2	no	19.787	14.800	EPSD	ICGC;COSMIC	16.704	Loss
AGC_PKC_PKCa_PRKCA_ST	Q8WZ42	TTN	P17252	PRKCA	T30724	R30726H	30726	Missense	proximal	2	no	18.805	13.781	EPSD	ICGC;COSMIC;CCLE	16.704	Loss
AGC_PKC_PKCa_PRKCA_ST	Q8WZ42	TTN	P17252	PRKCA	T30724	R30726C	30726	Missense	proximal	2	no	18.805	14.455	EPSD	ICGC;COSMIC	16.704	Loss
AGC_PKC_PKCa_PRKCA_ST	Q8WZ42	TTN	P17252	PRKCA	T30724	R30726S	30726	Missense	proximal	2	no	18.805	14.185	EPSD	ICGC	16.704	Loss
AGC_PKC_PKCa_PRKCA_ST	Q8WZ42	TTN	P17252	PRKCA	T30724	T30718N	30718	Missense	distal	-6	no	18.805	18.873	EPSD	ICGC;COSMIC	16.704	Up-regulation
AGC_PKC_PKCa_PRKCA_ST	Q8WZ42	TTN	P17252	PRKCA	T30724	T30729N	30729	Missense	distal	5	no	18.805	18.760	EPSD	ICGC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	Q8WZ42	TTN	P17252	PRKCA	T30724	K30722I	30722	Missense	proximal	-2	no	18.805	16.845	EPSD	ICGC;COSMIC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	Q8WZ42	TTN	P17252	PRKCA	S30855	P30859S	30859	Missense	distal	4	no	21.185	21.385	EPSD	ICGC;COSMIC	16.704	Up-regulation
AGC_PKC_PKCa_PRKCA_ST	Q8WZ42	TTN	P17252	PRKCA	S30855	E30851Q	30851	Missense	distal	-4	no	21.185	21.503	EPSD	ICGC;COSMIC	16.704	Up-regulation
AGC_PKC_PKCa_PRKCA_ST	Q8WZ42	TTN	P17252	PRKCA	S30855	R30853S	30853	Missense	proximal	-2	no	21.185	17.883	EPSD	ICGC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	Q8WZ42	TTN	P17252	PRKCA	S30855	I30858V	30858	Missense	distal	3	no	21.185	21.880	EPSD	ICGC;COSMIC	16.704	Up-regulation
AGC_PKC_PKCa_PRKCA_ST	Q8WZ42	TTN	P17252	PRKCA	S30855	R30857C	30857	Missense	proximal	2	no	21.185	16.834	EPSD	ICGC;COSMIC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	Q8WZ42	TTN	P17252	PRKCA	S30941	I30936F	30936	Missense	distal	-5	no	18.309	18.557	EPSD	ICGC;COSMIC	16.704	Up-regulation
AGC_PKC_PKCa_PRKCA_ST	Q8WZ42	TTN	P17252	PRKCA	S30941	T30934I	30934	Missense	distal	-7	no	18.309	18.303	EPSD	ICGC;COSMIC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	Q8WZ42	TTN	P17252	PRKCA	T31051	P31049R	31049	Missense	proximal	-2	no	15.275	18.317	EPSD	ICGC;COSMIC	16.704	Gain
AGC_PKC_PKCa_PRKCA_ST	Q8WZ42	TTN	P17252	PRKCA	S31105	A31108T	31108	Missense	distal	3	no	19.021	18.782	EPSD	ICGC;COSMIC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	Q8WZ42	TTN	P17252	PRKCA	S31105	R31107S	31107	Missense	proximal	2	no	19.021	14.401	EPSD	ICGC	16.704	Loss
AGC_PKC_PKCa_PRKCA_ST	Q8WZ42	TTN	P17252	PRKCA	S31105	A31108D	31108	Missense	distal	3	no	19.021	18.894	EPSD	ICGC;COSMIC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	Q8WZ42	TTN	P17252	PRKCA	S31509	R31513C	31513	Missense	distal	4	no	17.357	15.955	EPSD	ICGC;COSMIC	16.704	Loss
AGC_PKC_PKCa_PRKCA_ST	Q8WZ42	TTN	P17252	PRKCA	S31509	R31513H	31513	Missense	distal	4	no	17.357	17.074	EPSD	ICGC;COSMIC;CCLE	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	Q8WZ42	TTN	P17252	PRKCA	S31509	R31504L	31504	Missense	distal	-5	no	17.357	17.229	EPSD	ICGC;COSMIC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	Q8WZ42	TTN	P17252	PRKCA	S31509	R31504W	31504	Missense	distal	-5	no	17.357	17.043	EPSD	ICGC;COSMIC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	Q8WZ42	TTN	P17252	PRKCA	S31509	T31516A	31516	Missense	distal	7	no	17.357	17.348	EPSD	ICGC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	Q8WZ42	TTN	P17252	PRKCA	S31510	T31516A	31516	Missense	distal	6	no	16.662	16.740	EPSD	ICGC	16.704	Gain
AGC_PKC_PKCa_PRKCA_ST	Q8WZ42	TTN	P17252	PRKCA	S31800	I31799M	31799	Missense	proximal	-1	no	15.644	17.587	EPSD	ICGC;COSMIC	16.704	Gain
AGC_PKC_PKCa_PRKCA_ST	Q8WZ42	TTN	P17252	PRKCA	S32162	V32161F	32161	Missense	proximal	-1	no	16.441	17.196	EPSD	ICGC;COSMIC	16.704	Gain
AGC_PKC_PKCa_PRKCA_ST	Q8WZ42	TTN	P17252	PRKCA	S32162	E32157K	32157	Missense	distal	-5	no	16.441	16.736	EPSD	ICGC;COSMIC	16.704	Gain
AGC_PKC_PKCa_PRKCA_ST	Q8WZ42	TTN	P17252	PRKCA	S32311	T32308S	32308	Missense	distal	-3	no	15.989	17.282	EPSD	ICGC;COSMIC	16.704	Gain
AGC_PKC_PKCa_PRKCA_ST	Q8WZ42	TTN	P17252	PRKCA	S32312	T32308S	32308	Missense	distal	-4	no	18.878	19.540	EPSD	ICGC;COSMIC	16.704	Up-regulation
AGC_PKC_PKCa_PRKCA_ST	Q8WZ42	TTN	P17252	PRKCA	T32313	T32308S	32308	Missense	distal	-5	no	16.965	16.637	EPSD	ICGC;COSMIC	16.704	Loss
AGC_PKC_PKCa_PRKCA_ST	Q8WZ42	TTN	P17252	PRKCA	S32478	A32485D	32485	Missense	distal	7	no	18.634	18.638	EPSD	ICGC	16.704	Up-regulation
AGC_PKC_PKCa_PRKCA_ST	Q8WZ42	TTN	P17252	PRKCA	S32478	G32474C	32474	Missense	distal	-4	no	18.634	17.392	EPSD	ICGC;COSMIC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	Q8WZ42	TTN	P17252	PRKCA	S32478	I32476F	32476	Missense	proximal	-2	no	18.634	18.248	EPSD	ICGC;COSMIC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	Q8WZ42	TTN	P17252	PRKCA	S32478	S32483N	32483	Missense	distal	5	no	18.634	18.413	EPSD	ICGC;COSMIC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	Q8WZ42	TTN	P17252	PRKCA	S32491	E32493K	32493	Missense	proximal	2	no	14.335	19.614	EPSD	ICGC;COSMIC	16.704	Gain
AGC_PKC_PKCa_PRKCA_ST	Q8WZ42	TTN	P17252	PRKCA	T32599	R32605C	32605	Missense	distal	6	no	18.926	18.687	EPSD	ICGC;COSMIC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	Q8WZ42	TTN	P17252	PRKCA	T32599	R32605H	32605	Missense	distal	6	no	18.926	18.849	EPSD	ICGC;COSMIC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	Q8WZ42	TTN	P17252	PRKCA	T32599	R32606K	32606	Missense	distal	7	no	18.926	18.977	EPSD	ICGC;COSMIC	16.704	Up-regulation
AGC_PKC_PKCa_PRKCA_ST	Q8WZ42	TTN	P17252	PRKCA	T32599	K32601R	32601	Missense	proximal	2	no	18.926	19.348	EPSD	ICGC;COSMIC	16.704	Up-regulation
AGC_PKC_PKCa_PRKCA_ST	Q8WZ42	TTN	P17252	PRKCA	T32599	M32600I	32600	Missense	proximal	1	no	18.926	19.977	EPSD	ICGC	16.704	Up-regulation
AGC_PKC_PKCa_PRKCA_ST	Q8WZ42	TTN	P17252	PRKCA	T32599	R32597H	32597	Missense	proximal	-2	no	18.926	14.373	EPSD	ICGC;COSMIC;CCLE	16.704	Loss
AGC_PKC_PKCa_PRKCA_ST	Q8WZ42	TTN	P17252	PRKCA	T32599	R32606I	32606	Missense	distal	7	no	18.926	18.727	EPSD	ICGC;COSMIC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	Q8WZ42	TTN	P17252	PRKCA	T32599	K32602N	32602	Missense	distal	3	no	18.926	17.979	EPSD	ICGC;COSMIC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	Q8WZ42	TTN	P17252	PRKCA	T32599	R32597C	32597	Missense	proximal	-2	no	18.926	17.227	EPSD	ICGC;COSMIC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	Q8WZ42	TTN	P17252	PRKCA	T32609	R32605C	32605	Missense	distal	-4	no	17.831	16.488	EPSD	ICGC;COSMIC	16.704	Loss
AGC_PKC_PKCa_PRKCA_ST	Q8WZ42	TTN	P17252	PRKCA	T32609	R32605H	32605	Missense	distal	-4	no	17.831	17.257	EPSD	ICGC;COSMIC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	Q8WZ42	TTN	P17252	PRKCA	T32609	R32606K	32606	Missense	distal	-3	no	17.831	15.805	EPSD	ICGC;COSMIC	16.704	Loss
AGC_PKC_PKCa_PRKCA_ST	Q8WZ42	TTN	P17252	PRKCA	T32609	L32612I	32612	Missense	distal	3	no	17.831	17.520	EPSD	ICGC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	Q8WZ42	TTN	P17252	PRKCA	T32609	E32614K	32614	Missense	distal	5	no	17.831	18.245	EPSD	ICGC	16.704	Up-regulation
AGC_PKC_PKCa_PRKCA_ST	Q8WZ42	TTN	P17252	PRKCA	T32609	D32608N	32608	Missense	proximal	-1	no	17.831	18.169	EPSD	ICGC;COSMIC	16.704	Up-regulation
AGC_PKC_PKCa_PRKCA_ST	Q8WZ42	TTN	P17252	PRKCA	T32609	R32606I	32606	Missense	distal	-3	no	17.831	13.344	EPSD	ICGC;COSMIC	16.704	Loss
AGC_PKC_PKCa_PRKCA_ST	Q8WZ42	TTN	P17252	PRKCA	T32609	K32602N	32602	Missense	distal	-7	no	17.831	17.826	EPSD	ICGC;COSMIC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	Q8WZ42	TTN	P17252	PRKCA	T32752	P32750R	32750	Missense	proximal	-2	no	14.033	17.075	EPSD	ICGC	16.704	Gain
AGC_PKC_PKCa_PRKCA_ST	Q8WZ42	TTN	P17252	PRKCA	T32839	L32846I	32846	Missense	distal	7	no	17.494	17.338	EPSD	ICGC;COSMIC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	Q8WZ42	TTN	P17252	PRKCA	T32839	L32840V	32840	Missense	proximal	1	no	17.494	17.619	EPSD	ICGC;COSMIC	16.704	Up-regulation
AGC_PKC_PKCa_PRKCA_ST	Q8WZ42	TTN	P17252	PRKCA	T32839	D32837G	32837	Missense	proximal	-2	no	17.494	18.040	EPSD	ICGC;COSMIC	16.704	Up-regulation
AGC_PKC_PKCa_PRKCA_ST	Q8WZ42	TTN	P17252	PRKCA	T32839	K32834E	32834	Missense	distal	-5	no	17.494	17.200	EPSD	ICGC;COSMIC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	Q8WZ42	TTN	P17252	PRKCA	T32839	E32844K	32844	Missense	distal	5	no	17.494	17.908	EPSD	ICGC	16.704	Up-regulation
AGC_PKC_PKCa_PRKCA_ST	Q8WZ42	TTN	P17252	PRKCA	T32839	A32843V	32843	Missense	distal	4	no	17.494	16.156	EPSD	ICGC;COSMIC	16.704	Loss
AGC_PKC_PKCa_PRKCA_ST	Q8WZ42	TTN	P17252	PRKCA	T32877	R32883K	32883	Missense	distal	6	no	17.132	17.120	EPSD	ICGC;COSMIC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	Q8WZ42	TTN	P17252	PRKCA	T32877	F32882L	32882	Missense	distal	5	no	17.132	16.908	EPSD	ICGC;COSMIC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	Q8WZ42	TTN	P17252	PRKCA	T32877	E32881K	32881	Missense	distal	4	no	17.132	17.671	EPSD	ICGC	16.704	Up-regulation
AGC_PKC_PKCa_PRKCA_ST	Q8WZ42	TTN	P17252	PRKCA	T32877	A32872D	32872	Missense	distal	-5	no	17.132	17.227	EPSD	ICGC	16.704	Up-regulation
AGC_PKC_PKCa_PRKCA_ST	Q8WZ42	TTN	P17252	PRKCA	T32877	P32871L	32871	Missense	distal	-6	no	17.132	17.099	EPSD	ICGC;COSMIC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	Q8WZ42	TTN	P17252	PRKCA	T32998	D33002N	33002	Missense	distal	4	no	18.039	17.681	EPSD	ICGC;COSMIC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	Q8WZ42	TTN	P17252	PRKCA	T32998	R32995H	32995	Missense	distal	-3	no	18.039	14.183	EPSD	ICGC;COSMIC	16.704	Loss
AGC_PKC_PKCa_PRKCA_ST	Q8WZ42	TTN	P17252	PRKCA	T32998	Y33003H	33003	Missense	distal	5	no	18.039	17.894	EPSD	ICGC;COSMIC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	Q8WZ42	TTN	P17252	PRKCA	T32998	R32995S	32995	Missense	distal	-3	no	18.039	15.169	EPSD	ICGC	16.704	Loss
AGC_PKC_PKCa_PRKCA_ST	Q8WZ42	TTN	P17252	PRKCA	T32998	D33004E	33004	Missense	distal	6	no	18.039	18.022	EPSD	ICGC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	Q8WZ42	TTN	P17252	PRKCA	T32998	D33002G	33002	Missense	distal	4	no	18.039	18.034	EPSD	ICGC;COSMIC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	Q8WZ42	TTN	P17252	PRKCA	T32998	P33001S	33001	Missense	distal	3	no	18.039	18.179	EPSD	ICGC;COSMIC	16.704	Up-regulation
AGC_PKC_PKCa_PRKCA_ST	Q8WZ42	TTN	P17252	PRKCA	T32998	R32996Q	32996	Missense	proximal	-2	no	18.039	16.280	EPSD	ICGC;COSMIC	16.704	Loss
AGC_PKC_PKCa_PRKCA_ST	Q8WZ42	TTN	P17252	PRKCA	T32998	R32997H	32997	Missense	proximal	-1	no	18.039	17.716	EPSD	ICGC;COSMIC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	Q8WZ42	TTN	P17252	PRKCA	T32998	R32995C	32995	Missense	distal	-3	no	18.039	15.300	EPSD	ICGC	16.704	Loss
AGC_PKC_PKCa_PRKCA_ST	Q8WZ42	TTN	P17252	PRKCA	S33000	Y33003H	33003	Missense	distal	3	no	15.694	17.250	EPSD	ICGC;COSMIC	16.704	Gain
AGC_PKC_PKCa_PRKCA_ST	Q8WZ42	TTN	P17252	PRKCA	S33013	I33017V	33017	Missense	distal	4	no	20.242	20.365	EPSD	ICGC	16.704	Up-regulation
AGC_PKC_PKCa_PRKCA_ST	Q8WZ42	TTN	P17252	PRKCA	S33013	S33018T	33018	Missense	distal	5	no	20.242	20.067	EPSD	ICGC;COSMIC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	Q8WZ42	TTN	P17252	PRKCA	S33013	R33008Q	33008	Missense	distal	-5	no	20.242	20.090	EPSD	ICGC;COSMIC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	Q8WZ42	TTN	P17252	PRKCA	S33013	R33011K	33011	Missense	proximal	-2	no	20.242	18.615	EPSD	ICGC;COSMIC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	Q8WZ42	TTN	P17252	PRKCA	S33013	R33012C	33012	Missense	proximal	-1	no	20.242	17.582	EPSD	ICGC;COSMIC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	Q8WZ42	TTN	P17252	PRKCA	S33013	L33014I	33014	Missense	proximal	1	no	20.242	21.079	EPSD	ICGC	16.704	Up-regulation
AGC_PKC_PKCa_PRKCA_ST	Q8WZ42	TTN	P17252	PRKCA	S33013	S33013Y	33013	Missense	central	0	yes	20.242	0.000	EPSD	ICGC	16.704	Loss
AGC_PKC_PKCa_PRKCA_ST	Q8WZ42	TTN	P17252	PRKCA	S33066	P33072Q	33072	Missense	distal	6	no	17.363	17.279	EPSD	ICGC;COSMIC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	Q8WZ42	TTN	P17252	PRKCA	S33066	R33068C	33068	Missense	proximal	2	no	17.363	13.013	EPSD	ICGC;COSMIC	16.704	Loss
AGC_PKC_PKCa_PRKCA_ST	Q8WZ42	TTN	P17252	PRKCA	S33088	T33089I	33089	Missense	proximal	1	no	17.091	18.426	EPSD	ICGC;COSMIC	16.704	Up-regulation
AGC_PKC_PKCa_PRKCA_ST	Q8WZ42	TTN	P17252	PRKCA	S33088	H33091N	33091	Missense	distal	3	no	17.091	16.233	EPSD	ICGC	16.704	Loss
AGC_PKC_PKCa_PRKCA_ST	Q8WZ42	TTN	P17252	PRKCA	S33088	D33084E	33084	Missense	distal	-4	no	17.091	17.266	EPSD	ICGC	16.704	Up-regulation
AGC_PKC_PKCa_PRKCA_ST	Q8WZ42	TTN	P17252	PRKCA	S33088	D33084H	33084	Missense	distal	-4	no	17.091	17.388	EPSD	ICGC;COSMIC	16.704	Up-regulation
AGC_PKC_PKCa_PRKCA_ST	Q8WZ42	TTN	P17252	PRKCA	S33088	F33085L	33085	Missense	distal	-3	no	17.091	15.356	EPSD	ICGC	16.704	Loss
AGC_PKC_PKCa_PRKCA_ST	Q8WZ42	TTN	P17252	PRKCA	S33158	E33156Q	33156	Missense	proximal	-2	no	18.321	20.688	EPSD	ICGC;COSMIC	16.704	Up-regulation
AGC_PKC_PKCa_PRKCA_ST	Q8WZ42	TTN	P17252	PRKCA	S33158	F33151C	33151	Missense	distal	-7	no	18.321	18.314	EPSD	ICGC;COSMIC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	Q8WZ42	TTN	P17252	PRKCA	S33158	K33161I	33161	Missense	distal	3	no	18.321	16.394	EPSD	ICGC;COSMIC	16.704	Loss
AGC_PKC_PKCa_PRKCA_ST	Q8WZ42	TTN	P17252	PRKCA	S33158	E33156K	33156	Missense	proximal	-2	no	18.321	20.819	EPSD	ICGC;COSMIC	16.704	Up-regulation
AGC_PKC_PKCa_PRKCA_ST	Q8WZ42	TTN	P17252	PRKCA	S33158	F33151L	33151	Missense	distal	-7	no	18.321	18.323	EPSD	ICGC;COSMIC	16.704	Up-regulation
AGC_PKC_PKCa_PRKCA_ST	Q8WZ42	TTN	P17252	PRKCA	S33201	R33198Q	33198	Missense	distal	-3	no	18.473	15.615	EPSD	ICGC;COSMIC	16.704	Loss
AGC_PKC_PKCa_PRKCA_ST	Q8WZ42	TTN	P17252	PRKCA	S33201	R33200H	33200	Missense	proximal	-1	no	18.473	18.150	EPSD	ICGC;COSMIC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	Q8WZ42	TTN	P17252	PRKCA	T33231	E33228K	33228	Missense	distal	-3	no	14.430	17.342	EPSD	ICGC;COSMIC	16.704	Gain
AGC_PKC_PKCa_PRKCA_ST	Q8WZ42	TTN	P17252	PRKCA	S33245	P33243Q	33243	Missense	proximal	-2	no	15.507	16.790	EPSD	ICGC;COSMIC	16.704	Gain
AGC_PKC_PKCa_PRKCA_ST	Q8WZ42	TTN	P17252	PRKCA	S33251	S33254L	33254	Missense	distal	3	no	17.482	16.635	EPSD	ICGC;COSMIC	16.704	Loss
AGC_PKC_PKCa_PRKCA_ST	Q8WZ42	TTN	P17252	PRKCA	S33251	R33253K	33253	Missense	proximal	2	no	17.482	17.060	EPSD	ICGC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	Q8WZ42	TTN	P17252	PRKCA	S33251	R33244Q	33244	Missense	distal	-7	no	17.482	17.474	EPSD	ICGC;COSMIC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	Q8WZ42	TTN	P17252	PRKCA	S33256	S33254L	33254	Missense	proximal	-2	no	16.625	17.239	EPSD	ICGC;COSMIC	16.704	Gain
AGC_PKC_PKCa_PRKCA_ST	Q8WZ42	TTN	P17252	PRKCA	T33279	K33286N	33286	Missense	distal	7	no	16.903	16.783	EPSD	ICGC;COSMIC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	Q8WZ42	TTN	P17252	PRKCA	T33279	R33285K	33285	Missense	distal	6	no	16.903	16.891	EPSD	ICGC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	Q8WZ42	TTN	P17252	PRKCA	T33279	E33284K	33284	Missense	distal	5	no	16.903	17.317	EPSD	ICGC;COSMIC	16.704	Up-regulation
AGC_PKC_PKCa_PRKCA_ST	Q8WZ42	TTN	P17252	PRKCA	T33279	R33285M	33285	Missense	distal	6	no	16.903	16.830	EPSD	ICGC;COSMIC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	Q8WZ42	TTN	P17252	PRKCA	T33279	M33273T	33273	Missense	distal	-6	no	16.903	16.780	EPSD	ICGC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	Q8WZ42	TTN	P17252	PRKCA	T33329	E33331K	33331	Missense	proximal	2	no	13.178	18.457	EPSD	ICGC;COSMIC	16.704	Gain
AGC_PKC_PKCa_PRKCA_ST	Q8WZ42	TTN	P17252	PRKCA	S33400	D33404H	33404	Missense	distal	4	no	17.797	18.114	EPSD	ICGC;COSMIC	16.704	Up-regulation
AGC_PKC_PKCa_PRKCA_ST	Q8WZ42	TTN	P17252	PRKCA	S33400	R33402H	33402	Missense	proximal	2	no	17.797	12.774	EPSD	ICGC;COSMIC	16.704	Loss
AGC_PKC_PKCa_PRKCA_ST	Q8WZ42	TTN	P17252	PRKCA	S33400	R33402C	33402	Missense	proximal	2	no	17.797	13.447	EPSD	ICGC	16.704	Loss
AGC_PKC_PKCa_PRKCA_ST	Q8WZ42	TTN	P17252	PRKCA	S33400	Q33401K	33401	Missense	proximal	1	no	17.797	17.952	EPSD	ICGC	16.704	Up-regulation
AGC_PKC_PKCa_PRKCA_ST	Q8WZ42	TTN	P17252	PRKCA	S33400	T33396N	33396	Missense	distal	-4	no	17.797	18.129	EPSD	ICGC	16.704	Up-regulation
AGC_PKC_PKCa_PRKCA_ST	Q8WZ42	TTN	P17252	PRKCA	S33400	A33399V	33399	Missense	proximal	-1	no	17.797	16.894	EPSD	ICGC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	Q8WZ42	TTN	P17252	PRKCA	S33400	G33393E	33393	Missense	distal	-7	no	17.797	17.794	EPSD	ICGC;COSMIC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	Q8WZ42	TTN	P17252	PRKCA	S33400	D33394N	33394	Missense	distal	-6	no	17.797	17.825	EPSD	ICGC;COSMIC	16.704	Up-regulation
AGC_PKC_PKCa_PRKCA_ST	Q8WZ42	TTN	P17252	PRKCA	S33425	A33420V	33420	Missense	distal	-5	no	17.483	17.399	EPSD	ICGC;COSMIC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	Q8WZ42	TTN	P17252	PRKCA	S33425	A33422D	33422	Missense	distal	-3	no	17.483	16.889	EPSD	ICGC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	Q8WZ42	TTN	P17252	PRKCA	S33425	E33419K	33419	Missense	distal	-6	no	17.483	17.550	EPSD	ICGC;COSMIC	16.704	Up-regulation
AGC_PKC_PKCa_PRKCA_ST	Q8WZ42	TTN	P17252	PRKCA	S33437	R33439M	33439	Missense	proximal	2	no	17.345	12.897	EPSD	ICGC;COSMIC	16.704	Loss
AGC_PKC_PKCa_PRKCA_ST	Q8WZ42	TTN	P17252	PRKCA	S33437	R33439G	33439	Missense	proximal	2	no	17.345	12.099	EPSD	ICGC;COSMIC	16.704	Loss
AGC_PKC_PKCa_PRKCA_ST	Q8WZ42	TTN	P17252	PRKCA	S33437	E33440K	33440	Missense	distal	3	no	17.345	17.961	EPSD	ICGC;COSMIC	16.704	Up-regulation
AGC_PKC_PKCa_PRKCA_ST	Q8WZ42	TTN	P17252	PRKCA	T33446	T33448K	33448	Missense	proximal	2	no	15.132	19.521	EPSD	ICGC	16.704	Gain
AGC_PKC_PKCa_PRKCA_ST	Q8WZ42	TTN	P17252	PRKCA	S33451	T33448K	33448	Missense	distal	-3	no	16.593	18.730	EPSD	ICGC	16.704	Gain
AGC_PKC_PKCa_PRKCA_ST	Q8WZ42	TTN	P17252	PRKCA	S33451	E33450K	33450	Missense	proximal	-1	no	16.593	17.019	EPSD	ICGC;COSMIC	16.704	Gain
AGC_PKC_PKCa_PRKCA_ST	Q8WZ42	TTN	P17252	PRKCA	T33498	R33495W	33495	Missense	distal	-3	no	17.246	14.892	EPSD	ICGC;COSMIC	16.704	Loss
AGC_PKC_PKCa_PRKCA_ST	Q8WZ42	TTN	P17252	PRKCA	T33498	E33503K	33503	Missense	distal	5	no	17.246	17.659	EPSD	ICGC;COSMIC	16.704	Up-regulation
AGC_PKC_PKCa_PRKCA_ST	Q8WZ42	TTN	P17252	PRKCA	T33498	A33505E	33505	Missense	distal	7	no	17.246	17.198	EPSD	ICGC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	Q8WZ42	TTN	P17252	PRKCA	T33498	S33496F	33496	Missense	proximal	-2	no	17.246	16.574	EPSD	ICGC;COSMIC	16.704	Loss
AGC_PKC_PKCa_PRKCA_ST	Q8WZ42	TTN	P17252	PRKCA	T33498	L33491I	33491	Missense	distal	-7	no	17.246	17.242	EPSD	ICGC;COSMIC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	Q8WZ42	TTN	P17252	PRKCA	T33498	R33495Q	33495	Missense	distal	-3	no	17.246	14.388	EPSD	ICGC;COSMIC	16.704	Loss
AGC_PKC_PKCa_PRKCA_ST	Q8WZ42	TTN	P17252	PRKCA	S33531	R33533H	33533	Missense	proximal	2	no	17.815	12.791	EPSD	ICGC;COSMIC	16.704	Loss
AGC_PKC_PKCa_PRKCA_ST	Q8WZ42	TTN	P17252	PRKCA	S33531	R33533C	33533	Missense	proximal	2	no	17.815	13.464	EPSD	ICGC	16.704	Loss
AGC_PKC_PKCa_PRKCA_ST	Q8WZ42	TTN	P17252	PRKCA	S33608	R33611Q	33611	Missense	distal	3	no	17.326	14.872	EPSD	ICGC;COSMIC	16.704	Loss
AGC_PKC_PKCa_PRKCA_ST	Q8WZ42	TTN	P17252	PRKCA	S33608	S33608F	33608	Missense	central	0	yes	17.326	0.000	EPSD	ICGC;COSMIC	16.704	Loss
AGC_PKC_PKCa_PRKCA_ST	Q8WZ42	TTN	P17252	PRKCA	S33608	S33608C	33608	Missense	central	0	yes	17.326	0.000	EPSD	ICGC;COSMIC	16.704	Loss
AGC_PKC_PKCa_PRKCA_ST	Q8WZ42	TTN	P17252	PRKCA	S33608	S33608Y	33608	Missense	central	0	yes	17.326	0.000	EPSD	ICGC	16.704	Loss
AGC_PKC_PKCa_PRKCA_ST	Q8WZ42	TTN	P17252	PRKCA	S33624	T33626K	33626	Missense	proximal	2	no	14.038	18.426	EPSD	ICGC	16.704	Gain
AGC_PKC_PKCa_PRKCA_ST	Q8WZ42	TTN	P17252	PRKCA	S33900	E33898K	33898	Missense	proximal	-2	no	15.745	18.243	EPSD	ICGC;COSMIC;CCLE	16.704	Gain
AGC_PKC_PKCa_PRKCA_ST	Q8WZ42	TTN	P17252	PRKCA	S33976	E33979K	33979	Missense	distal	3	no	16.646	17.262	EPSD	ICGC;COSMIC	16.704	Gain
AGC_PKC_PKCa_PRKCA_ST	Q8WZ42	TTN	P17252	PRKCA	S34108	S34105L	34105	Missense	distal	-3	no	17.096	15.610	EPSD	ICGC;COSMIC	16.704	Loss
AGC_PKC_PKCa_PRKCA_ST	Q8WZ42	TTN	P17252	PRKCA	S34108	R34113K	34113	Missense	distal	5	no	17.096	17.240	EPSD	ICGC	16.704	Up-regulation
AGC_PKC_PKCa_PRKCA_ST	Q8WZ42	TTN	P17252	PRKCA	S34108	S34104Y	34104	Missense	distal	-4	no	17.096	16.902	EPSD	ICGC;COSMIC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	Q8WZ42	TTN	P17252	PRKCA	S34108	R34111H	34111	Missense	distal	3	no	17.096	16.383	EPSD	ICGC;COSMIC	16.704	Loss
AGC_PKC_PKCa_PRKCA_ST	Q8WZ42	TTN	P17252	PRKCA	S34108	R34111C	34111	Missense	distal	3	no	17.096	14.477	EPSD	ICGC;COSMIC	16.704	Loss
AGC_PKC_PKCa_PRKCA_ST	Q8WZ42	TTN	P17252	PRKCA	S34108	S34102Y	34102	Missense	distal	-6	no	17.096	17.042	EPSD	ICGC;COSMIC;CCLE	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	Q8WZ42	TTN	P17252	PRKCA	S34108	V34115A	34115	Missense	distal	7	no	17.096	17.150	EPSD	ICGC	16.704	Up-regulation
AGC_PKC_PKCa_PRKCA_ST	Q8WZ42	TTN	P17252	PRKCA	S34108	S34104T	34104	Missense	distal	-4	no	17.096	16.434	EPSD	ICGC	16.704	Loss
AGC_PKC_PKCa_PRKCA_ST	Q8WZ42	TTN	P17252	PRKCA	S34108	S34104A	34104	Missense	distal	-4	no	17.096	17.183	EPSD	ICGC;COSMIC	16.704	Up-regulation
AGC_PKC_PKCa_PRKCA_ST	P49841	GSK3B	P17252	PRKCA	T7	A11S	11	Missense	distal	4	no	17.165	17.149	EPSD	ICGC;COSMIC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	P49841	GSK3B	P17252	PRKCA	S9	A11S	11	Missense	proximal	2	no	20.161	20.239	PhosphoSitePlus	ICGC;COSMIC	16.704	Up-regulation
AGC_PKC_PKCa_PRKCA_ST	P49841	GSK3B	P17252	PRKCA	S13	A11S	11	Missense	proximal	-2	no	17.093	16.877	EPSD	ICGC;COSMIC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	P49841	GSK3B	P17252	PRKCA	S147	P154H	154	Missense	distal	7	no	17.546	17.484	EPSD	ICGC;COSMIC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	P49841	GSK3B	P17252	PRKCA	S147	A149D	149	Missense	proximal	2	no	17.546	16.965	EPSD	ICGC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	P49841	GSK3B	P17252	PRKCA	S147	T152R	152	Missense	distal	5	no	17.546	17.863	EPSD	ICGC;COSMIC	16.704	Up-regulation
AGC_PKC_PKCa_PRKCA_ST	P49841	GSK3B	P17252	PRKCA	S147	Q151R	151	Missense	distal	4	no	17.546	17.763	EPSD	ICGC;COSMIC	16.704	Up-regulation
AGC_PKC_PKCa_PRKCA_ST	P35579	MYH9	P17252	PRKCA	S36	D37N	37	Missense	proximal	1	no	19.356	19.828	EPSD	ICGC;COSMIC	16.704	Up-regulation
AGC_PKC_PKCa_PRKCA_ST	P35579	MYH9	P17252	PRKCA	S36	P43T	43	Missense	distal	7	no	19.356	19.327	EPSD	ICGC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	P35579	MYH9	P17252	PRKCA	S36	D37E	37	Missense	proximal	1	no	19.356	19.389	EPSD	ICGC	16.704	Up-regulation
AGC_PKC_PKCa_PRKCA_ST	P35579	MYH9	P17252	PRKCA	S197	Y193H	193	Missense	distal	-4	no	17.215	17.027	EPSD	ICGC;COSMIC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	P35579	MYH9	P17252	PRKCA	S197	H198N	198	Missense	proximal	1	no	17.215	16.901	EPSD	ICGC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	P35579	MYH9	P17252	PRKCA	T226	N223K	223	Missense	distal	-3	no	15.057	17.257	EPSD	ICGC	16.704	Gain
AGC_PKC_PKCa_PRKCA_ST	P35579	MYH9	P17252	PRKCA	S304	L303R	303	Missense	proximal	-1	no	16.096	16.902	EPSD	ICGC	16.704	Gain
AGC_PKC_PKCa_PRKCA_ST	P35579	MYH9	P17252	PRKCA	T638	G634W	634	Missense	distal	-4	no	16.837	16.112	EPSD	ICGC;COSMIC	16.704	Loss
AGC_PKC_PKCa_PRKCA_ST	P35579	MYH9	P17252	PRKCA	S1122	R1124C	1124	Missense	proximal	2	no	17.484	13.133	EPSD	ICGC	16.704	Loss
AGC_PKC_PKCa_PRKCA_ST	P35579	MYH9	P17252	PRKCA	S1122	R1124S	1124	Missense	proximal	2	no	17.484	12.864	EPSD	ICGC	16.704	Loss
AGC_PKC_PKCa_PRKCA_ST	P35579	MYH9	P17252	PRKCA	S1122	R1127G	1127	Missense	distal	5	no	17.484	17.202	EPSD	ICGC;COSMIC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	P35579	MYH9	P17252	PRKCA	S1122	N1128Y	1128	Missense	distal	6	no	17.484	17.605	EPSD	ICGC;COSMIC	16.704	Up-regulation
AGC_PKC_PKCa_PRKCA_ST	P35579	MYH9	P17252	PRKCA	S1126	R1124C	1124	Missense	proximal	-2	no	17.515	15.815	EPSD	ICGC	16.704	Loss
AGC_PKC_PKCa_PRKCA_ST	P35579	MYH9	P17252	PRKCA	S1126	R1124S	1124	Missense	proximal	-2	no	17.515	14.213	EPSD	ICGC	16.704	Loss
AGC_PKC_PKCa_PRKCA_ST	P35579	MYH9	P17252	PRKCA	S1126	R1127G	1127	Missense	proximal	1	no	17.515	16.562	EPSD	ICGC;COSMIC	16.704	Loss
AGC_PKC_PKCa_PRKCA_ST	P35579	MYH9	P17252	PRKCA	S1126	N1128Y	1128	Missense	proximal	2	no	17.515	18.390	EPSD	ICGC;COSMIC	16.704	Up-regulation
AGC_PKC_PKCa_PRKCA_ST	P35579	MYH9	P17252	PRKCA	S1294	Q1291R	1291	Missense	distal	-3	no	15.964	18.822	EPSD	ICGC;COSMIC	16.704	Gain
AGC_PKC_PKCa_PRKCA_ST	P35579	MYH9	P17252	PRKCA	S1326	L1331R	1331	Missense	distal	5	no	16.493	16.825	EPSD	ICGC;COSMIC	16.704	Gain
AGC_PKC_PKCa_PRKCA_ST	P35579	MYH9	P17252	PRKCA	S1328	L1331R	1331	Missense	distal	3	no	18.263	20.501	EPSD	ICGC;COSMIC	16.704	Up-regulation
AGC_PKC_PKCa_PRKCA_ST	P35579	MYH9	P17252	PRKCA	S1328	L1327P	1327	Missense	proximal	-1	no	18.263	18.383	EPSD	ICGC	16.704	Up-regulation
AGC_PKC_PKCa_PRKCA_ST	P35579	MYH9	P17252	PRKCA	S1328	S1326R	1326	Missense	proximal	-2	no	18.263	21.565	EPSD	ICGC;COSMIC	16.704	Up-regulation
AGC_PKC_PKCa_PRKCA_ST	P35579	MYH9	P17252	PRKCA	T1329	L1331R	1331	Missense	proximal	2	no	13.422	18.408	EPSD	ICGC;COSMIC	16.704	Gain
AGC_PKC_PKCa_PRKCA_ST	P35579	MYH9	P17252	PRKCA	S1340	S1340Y	1340	Missense	central	0	yes	18.230	0.000	EPSD	ICGC	16.704	Loss
AGC_PKC_PKCa_PRKCA_ST	P35579	MYH9	P17252	PRKCA	S1480	S1480L	1480	Missense	central	0	yes	17.106	0.000	EPSD	ICGC;COSMIC	16.704	Loss
AGC_PKC_PKCa_PRKCA_ST	P35579	MYH9	P17252	PRKCA	S1480	R1483Q	1483	Missense	distal	3	no	17.106	14.653	EPSD	ICGC;COSMIC	16.704	Loss
AGC_PKC_PKCa_PRKCA_ST	P35579	MYH9	P17252	PRKCA	S1511	T1504M	1504	Missense	distal	-7	no	17.674	17.679	EPSD	ICGC;COSMIC	16.704	Up-regulation
AGC_PKC_PKCa_PRKCA_ST	P35579	MYH9	P17252	PRKCA	S1526	R1528L	1528	Missense	proximal	2	no	17.059	12.073	EPSD	ICGC;COSMIC	16.704	Loss
AGC_PKC_PKCa_PRKCA_ST	P35579	MYH9	P17252	PRKCA	S1714	D1708E	1708	Missense	distal	-6	no	17.204	17.287	EPSD	ICGC	16.704	Up-regulation
AGC_PKC_PKCa_PRKCA_ST	P35579	MYH9	P17252	PRKCA	S1869	D1866N	1866	Missense	distal	-3	no	17.616	18.431	EPSD	ICGC;COSMIC	16.704	Up-regulation
AGC_PKC_PKCa_PRKCA_ST	P35579	MYH9	P17252	PRKCA	S1869	L1875I	1875	Missense	distal	6	no	17.616	17.592	EPSD	ICGC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	P35579	MYH9	P17252	PRKCA	S1892	R1888Q	1888	Missense	distal	-4	no	17.709	17.332	EPSD	ICGC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	P35579	MYH9	P17252	PRKCA	S1892	R1893S	1893	Missense	proximal	1	no	17.709	16.535	EPSD	ICGC;COSMIC	16.704	Loss
AGC_PKC_PKCa_PRKCA_ST	P35579	MYH9	P17252	PRKCA	S1892	R1893L	1893	Missense	proximal	1	no	17.709	17.361	EPSD	ICGC;COSMIC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	P35579	MYH9	P17252	PRKCA	S1892	R1893G	1893	Missense	proximal	1	no	17.709	16.756	EPSD	ICGC;COSMIC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	P35579	MYH9	P17252	PRKCA	S1916	R1912C	1912	Missense	distal	-4	no	18.869	17.525	PhosphoSitePlus	ICGC;COSMIC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	P17812	CTPS1	P17252	PRKCA	T455	K460N	460	Missense	distal	5	no	18.711	18.205	PhosphoSitePlus;EPSD	ICGC;CCLE	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	P17812	CTPS1	P17252	PRKCA	T455	Q458K	458	Missense	distal	3	no	18.711	20.542	PhosphoSitePlus;EPSD	ICGC;COSMIC	16.704	Up-regulation
AGC_PKC_PKCa_PRKCA_ST	P17812	CTPS1	P17252	PRKCA	T455	Q458H	458	Missense	distal	3	no	18.711	20.452	PhosphoSitePlus;EPSD	ICGC;COSMIC	16.704	Up-regulation
AGC_PKC_PKCa_PRKCA_ST	P17812	CTPS1	P17252	PRKCA	T455	Q458R	458	Missense	distal	3	no	18.711	21.164	PhosphoSitePlus;EPSD	ICGC;COSMIC	16.704	Up-regulation
AGC_PKC_PKCa_PRKCA_ST	P17812	CTPS1	P17252	PRKCA	S462	Q458K	458	Missense	distal	-4	no	16.508	16.920	EPSD;PhosphoSitePlus	ICGC;COSMIC	16.704	Gain
AGC_PKC_PKCa_PRKCA_ST	P17812	CTPS1	P17252	PRKCA	S462	Q458R	458	Missense	distal	-4	no	16.508	16.885	EPSD;PhosphoSitePlus	ICGC;COSMIC	16.704	Gain
AGC_PKC_PKCa_PRKCA_ST	P17812	CTPS1	P17252	PRKCA	S562	D565N	565	Missense	distal	3	no	20.243	20.398	EPSD	ICGC	16.704	Up-regulation
AGC_PKC_PKCa_PRKCA_ST	P17812	CTPS1	P17252	PRKCA	S568	D565N	565	Missense	distal	-3	no	16.196	17.012	EPSD	ICGC	16.704	Gain
AGC_PKC_PKCa_PRKCA_ST	Q16658	FSCN1	P17252	PRKCA	S39	V33L	33	Missense	distal	-6	no	20.677	20.725	PhosphoSitePlus	ICGC	16.704	Up-regulation
AGC_PKC_PKCa_PRKCA_ST	Q16658	FSCN1	P17252	PRKCA	S187	Q182H	182	Missense	distal	-5	no	17.746	17.543	EPSD	ICGC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	Q16658	FSCN1	P17252	PRKCA	S187	A180T	180	Missense	distal	-7	no	17.746	17.741	EPSD	ICGC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	Q16658	FSCN1	P17252	PRKCA	S218	E215Q	215	Missense	distal	-3	no	15.267	17.348	EPSD	ICGC;COSMIC;CCLE	16.704	Gain
AGC_PKC_PKCa_PRKCA_ST	Q16658	FSCN1	P17252	PRKCA	S274	D280N	280	Missense	distal	6	no	18.660	18.576	EPSD	ICGC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	O00168	FXYD1	P17252	PRKCA	S83	R81S	81	Missense	proximal	-2	no	20.721	17.419	EPSD	ICGC;COSMIC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	O00168	FXYD1	P17252	PRKCA	S83	R85S	85	Missense	proximal	2	no	20.721	16.102	EPSD	ICGC;COSMIC	16.704	Loss
AGC_PKC_PKCa_PRKCA_ST	O00168	FXYD1	P17252	PRKCA	S88	R81S	81	Missense	distal	-7	no	22.299	22.294	PhosphoSitePlus	ICGC;COSMIC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	O00168	FXYD1	P17252	PRKCA	S88	R85S	85	Missense	distal	-3	no	22.299	19.430	PhosphoSitePlus	ICGC;COSMIC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	O00168	FXYD1	P17252	PRKCA	T89	R85S	85	Missense	distal	-4	no	18.283	18.090	EPSD	ICGC;COSMIC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	Q15717	ELAVL1	P17252	PRKCA	T118	G112R	112	Missense	distal	-6	no	20.443	20.551	EPSD	ICGC;COSMIC	16.704	Up-regulation
AGC_PKC_PKCa_PRKCA_ST	Q15717	ELAVL1	P17252	PRKCA	T118	R115W	115	Missense	distal	-3	no	20.443	18.089	EPSD	ICGC;COSMIC;GDSC;CCLE	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	Q15717	ELAVL1	P17252	PRKCA	T118	T116N	116	Missense	proximal	-2	no	20.443	20.141	EPSD	ICGC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	Q15717	ELAVL1	P17252	PRKCA	T118	T118N	118	Missense	central	0	yes	20.443	0.000	EPSD	ICGC	16.704	Loss
AGC_PKC_PKCa_PRKCA_ST	Q15717	ELAVL1	P17252	PRKCA	T118	G112W	112	Missense	distal	-6	no	20.443	20.266	EPSD	ICGC;COSMIC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	Q15717	ELAVL1	P17252	PRKCA	T118	Q119K	119	Missense	proximal	1	no	20.443	20.598	EPSD	ICGC;COSMIC	16.704	Up-regulation
AGC_PKC_PKCa_PRKCA_ST	Q15717	ELAVL1	P17252	PRKCA	T118	L113H	113	Missense	distal	-5	no	20.443	20.216	EPSD	ICGC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	Q15717	ELAVL1	P17252	PRKCA	S221	A215V	215	Missense	distal	-6	no	18.232	18.155	PhosphoSitePlus;EPSD	ICGC;COSMIC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	Q15717	ELAVL1	P17252	PRKCA	S221	S221F	221	Missense	central	0	yes	18.232	0.000	PhosphoSitePlus;EPSD	ICGC;COSMIC	16.704	Loss
AGC_PKC_PKCa_PRKCA_ST	Q15717	ELAVL1	P17252	PRKCA	S221	G224C	224	Missense	distal	3	no	18.232	16.253	PhosphoSitePlus;EPSD	ICGC	16.704	Loss
AGC_PKC_PKCa_PRKCA_ST	Q15717	ELAVL1	P17252	PRKCA	S221	F218L	218	Missense	distal	-3	no	18.232	16.497	PhosphoSitePlus;EPSD	ICGC	16.704	Loss
AGC_PKC_PKCa_PRKCA_ST	Q15717	ELAVL1	P17252	PRKCA	S221	Q216R	216	Missense	distal	-5	no	18.232	18.384	PhosphoSitePlus;EPSD	ICGC;COSMIC	16.704	Up-regulation
AGC_PKC_PKCa_PRKCA_ST	P07355	ANXA2	P17252	PRKCA	S12	T19A	19	Missense	distal	7	no	17.130	17.122	EPSD;PhosphoSitePlus	ICGC;COSMIC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	P07355	ANXA2	P17252	PRKCA	S12	E6K	6	Missense	distal	-6	no	17.130	17.197	EPSD;PhosphoSitePlus	ICGC;COSMIC	16.704	Up-regulation
AGC_PKC_PKCa_PRKCA_ST	P07355	ANXA2	P17252	PRKCA	S12	E14D	14	Missense	proximal	2	no	17.130	17.552	EPSD;PhosphoSitePlus	ICGC;COSMIC	16.704	Up-regulation
AGC_PKC_PKCa_PRKCA_ST	P07355	ANXA2	P17252	PRKCA	S12	S18C	18	Missense	distal	6	no	17.130	16.962	EPSD;PhosphoSitePlus	ICGC;COSMIC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	P07355	ANXA2	P17252	PRKCA	S12	K10M	10	Missense	proximal	-2	no	17.130	16.776	EPSD;PhosphoSitePlus	ICGC;COSMIC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	P07355	ANXA2	P17252	PRKCA	S12	S18F	18	Missense	distal	6	no	17.130	17.089	EPSD;PhosphoSitePlus	ICGC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	P07355	ANXA2	P17252	PRKCA	S26	T19A	19	Missense	distal	-7	no	17.978	17.982	PhosphoSitePlus;EPSD	ICGC;COSMIC	16.704	Up-regulation
AGC_PKC_PKCa_PRKCA_ST	P07355	ANXA2	P17252	PRKCA	S26	Y30C	30	Missense	distal	4	no	17.978	17.220	PhosphoSitePlus;EPSD	ICGC;COSMIC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	P07355	ANXA2	P17252	PRKCA	S26	P21T	21	Missense	distal	-5	no	17.978	17.980	PhosphoSitePlus;EPSD	ICGC;COSMIC	16.704	Up-regulation
AGC_PKC_PKCa_PRKCA_ST	P07355	ANXA2	P17252	PRKCA	S117	D124N	124	Missense	distal	7	no	17.198	17.171	EPSD	ICGC;COSMIC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	P07355	ANXA2	P17252	PRKCA	S117	T123P	123	Missense	distal	6	no	17.198	17.279	EPSD	ICGC;COSMIC	16.704	Up-regulation
AGC_PKC_PKCa_PRKCA_ST	P07355	ANXA2	P17252	PRKCA	S117	S117F	117	Missense	central	0	yes	17.198	0.000	EPSD	ICGC;COSMIC	16.704	Loss
AGC_PKC_PKCa_PRKCA_ST	P07355	ANXA2	P17252	PRKCA	S117	L114I	114	Missense	distal	-3	no	17.198	17.066	EPSD	ICGC;COSMIC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	P07355	ANXA2	P17252	PRKCA	S234	P237H	237	Missense	distal	3	no	16.119	16.938	EPSD	ICGC;COSMIC	16.704	Gain
AGC_PKC_PKCa_PRKCA_ST	P07355	ANXA2	P17252	PRKCA	S243	S236N	236	Missense	distal	-7	no	19.055	19.050	EPSD	ICGC;COSMIC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	P07355	ANXA2	P17252	PRKCA	S243	R245S	245	Missense	proximal	2	no	19.055	14.435	EPSD	ICGC	16.704	Loss
AGC_PKC_PKCa_PRKCA_ST	P07355	ANXA2	P17252	PRKCA	S243	P237H	237	Missense	distal	-6	no	19.055	19.092	EPSD	ICGC;COSMIC	16.704	Up-regulation
AGC_PKC_PKCa_PRKCA_ST	P07355	ANXA2	P17252	PRKCA	S243	M240T	240	Missense	distal	-3	no	19.055	17.864	EPSD	ICGC;COSMIC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	P07355	ANXA2	P17252	PRKCA	S277	R273W	273	Missense	distal	-4	no	17.621	16.794	EPSD	ICGC;COSMIC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	P07355	ANXA2	P17252	PRKCA	S277	R284Q	284	Missense	distal	7	no	17.621	17.616	EPSD	ICGC;COSMIC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	P07355	ANXA2	P17252	PRKCA	S277	G280D	280	Missense	distal	3	no	17.621	16.535	EPSD	ICGC	16.704	Loss
AGC_PKC_PKCa_PRKCA_ST	Q9UQ80	PA2G4	P17252	PRKCA	S2	Q7K	7	Missense	distal	5	no	17.394	17.547	EPSD	ICGC;COSMIC	16.704	Up-regulation
AGC_PKC_PKCa_PRKCA_ST	Q9UQ80	PA2G4	P17252	PRKCA	S252	I246V	246	Missense	distal	-6	no	17.758	17.742	EPSD	ICGC;COSMIC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	Q9UQ80	PA2G4	P17252	PRKCA	T261	F265L	265	Missense	distal	4	no	18.343	17.912	EPSD	ICGC;COSMIC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	Q9UQ80	PA2G4	P17252	PRKCA	T261	E268G	268	Missense	distal	7	no	18.343	18.414	EPSD	ICGC;COSMIC	16.704	Up-regulation
AGC_PKC_PKCa_PRKCA_ST	Q9UQ80	PA2G4	P17252	PRKCA	T261	E268K	268	Missense	distal	7	no	18.343	18.489	EPSD	ICGC;COSMIC	16.704	Up-regulation
AGC_PKC_PKCa_PRKCA_ST	Q9UQ80	PA2G4	P17252	PRKCA	S361	L354I	354	Missense	distal	-7	no	17.625	17.621	EPSD	ICGC;COSMIC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	Q9UQ80	PA2G4	P17252	PRKCA	S361	Q367K	367	Missense	distal	6	no	17.625	17.735	EPSD	ICGC;COSMIC	16.704	Up-regulation
AGC_PKC_PKCa_PRKCA_ST	Q9UQ80	PA2G4	P17252	PRKCA	S363	Q367K	367	Missense	distal	4	no	19.396	19.785	EPSD	ICGC;COSMIC	16.704	Up-regulation
AGC_PKC_PKCa_PRKCA_ST	Q9UQ80	PA2G4	P17252	PRKCA	T366	Q367K	367	Missense	proximal	1	no	22.111	22.265	EPSD;PhosphoSitePlus	ICGC;COSMIC	16.704	Up-regulation
AGC_PKC_PKCa_PRKCA_ST	P21359	NF1	P17252	PRKCA	S302	K296N	296	Missense	distal	-6	no	18.764	18.640	EPSD	ICGC;COSMIC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	P21359	NF1	P17252	PRKCA	S302	K297N	297	Missense	distal	-5	no	18.764	18.421	EPSD	ICGC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	P21359	NF1	P17252	PRKCA	S302	S302I	302	Missense	central	0	yes	18.764	0.000	EPSD	ICGC	16.704	Loss
AGC_PKC_PKCa_PRKCA_ST	P21359	NF1	P17252	PRKCA	S302	R304G	304	Missense	proximal	2	no	18.764	13.518	EPSD	ICGC;COSMIC	16.704	Loss
AGC_PKC_PKCa_PRKCA_ST	P21359	NF1	P17252	PRKCA	S657	P654L	654	Missense	distal	-3	no	18.653	18.146	EPSD	ICGC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	P21359	NF1	P17252	PRKCA	S657	R659Q	659	Missense	proximal	2	no	18.653	14.819	EPSD	ICGC;COSMIC	16.704	Loss
AGC_PKC_PKCa_PRKCA_ST	P21359	NF1	P17252	PRKCA	S858	S856I	856	Missense	proximal	-2	no	16.837	16.551	EPSD	ICGC	16.704	Loss
AGC_PKC_PKCa_PRKCA_ST	P21359	NF1	P17252	PRKCA	S858	S856R	856	Missense	proximal	-2	no	16.837	20.139	EPSD	ICGC;COSMIC	16.704	Up-regulation
AGC_PKC_PKCa_PRKCA_ST	P21359	NF1	P17252	PRKCA	S858	G859C	859	Missense	proximal	1	no	16.837	14.954	EPSD	ICGC	16.704	Loss
AGC_PKC_PKCa_PRKCA_ST	P21359	NF1	P17252	PRKCA	S1140	R1136Q	1136	Missense	distal	-4	no	23.101	22.724	EPSD	ICGC;COSMIC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	P21359	NF1	P17252	PRKCA	S1140	R1136L	1136	Missense	distal	-4	no	23.101	22.477	EPSD	ICGC;COSMIC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	P21359	NF1	P17252	PRKCA	S2181	A2177S	2177	Missense	distal	-4	no	24.251	24.164	EPSD	ICGC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	P21359	NF1	P17252	PRKCA	S2515	G2512S	2512	Missense	distal	-3	no	19.017	19.409	EPSD	ICGC;COSMIC;GDSC;CCLE	16.704	Up-regulation
AGC_PKC_PKCa_PRKCA_ST	P21359	NF1	P17252	PRKCA	S2523	G2527V	2527	Missense	distal	4	no	17.566	16.602	EPSD	ICGC;COSMIC	16.704	Loss
AGC_PKC_PKCa_PRKCA_ST	P21359	NF1	P17252	PRKCA	S2523	G2527W	2527	Missense	distal	4	no	17.566	16.633	EPSD	ICGC;COSMIC	16.704	Loss
AGC_PKC_PKCa_PRKCA_ST	P21359	NF1	P17252	PRKCA	S2523	L2524M	2524	Missense	proximal	1	no	17.566	17.352	EPSD	ICGC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	P21359	NF1	P17252	PRKCA	S2530	G2527W	2527	Missense	distal	-3	no	16.187	17.095	EPSD	ICGC;COSMIC	16.704	Gain
AGC_PKC_PKCa_PRKCA_ST	P21359	NF1	P17252	PRKCA	S2597	L2604V	2604	Missense	distal	7	no	17.185	17.126	EPSD	ICGC;COSMIC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	P21359	NF1	P17252	PRKCA	S2810	R2814H	2814	Missense	distal	4	no	20.229	19.946	EPSD	ICGC;COSMIC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	P21359	NF1	P17252	PRKCA	S2810	G2806C	2806	Missense	distal	-4	no	20.229	18.987	EPSD	ICGC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	O75469	NR1I2	P17252	PRKCA	S8	E2K	2	Missense	distal	-6	no	18.617	18.684	EPSD	ICGC	16.704	Up-regulation
AGC_PKC_PKCa_PRKCA_ST	O75469	NR1I2	P17252	PRKCA	S8	H11L	11	Missense	distal	3	no	18.617	17.091	EPSD	ICGC;COSMIC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	O75469	NR1I2	P17252	PRKCA	S8	W9C	9	Missense	proximal	1	no	18.617	16.505	EPSD	ICGC;COSMIC	16.704	Loss
AGC_PKC_PKCa_PRKCA_ST	O75469	NR1I2	P17252	PRKCA	S8	V15I	15	Missense	distal	7	no	18.617	18.520	EPSD	ICGC;COSMIC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	O75469	NR1I2	P17252	PRKCA	S8	D13G	13	Missense	distal	5	no	18.617	18.697	EPSD	ICGC	16.704	Up-regulation
AGC_PKC_PKCa_PRKCA_ST	P30086	PEBP1	P17252	PRKCA	S60	D56G	56	Missense	distal	-4	no	17.037	17.806	EPSD	ICGC	16.704	Up-regulation
AGC_PKC_PKCa_PRKCA_ST	Q05193	DNM1	P17252	PRKCA	S126	H128R	128	Missense	proximal	2	no	13.808	18.832	EPSD	ICGC;COSMIC	16.704	Gain
AGC_PKC_PKCa_PRKCA_ST	Q05193	DNM1	P17252	PRKCA	S264	F258L	258	Missense	distal	-6	no	18.801	18.821	EPSD	ICGC;COSMIC	16.704	Up-regulation
AGC_PKC_PKCa_PRKCA_ST	Q05193	DNM1	P17252	PRKCA	T443	C442F	442	Missense	proximal	-1	no	18.871	20.436	EPSD	ICGC	16.704	Up-regulation
AGC_PKC_PKCa_PRKCA_ST	Q05193	DNM1	P17252	PRKCA	T443	K445N	445	Missense	proximal	2	no	18.871	13.922	EPSD	ICGC;COSMIC	16.704	Loss
AGC_PKC_PKCa_PRKCA_ST	Q05193	DNM1	P17252	PRKCA	S619	E612D	612	Missense	distal	-7	no	19.028	19.031	EPSD	ICGC	16.704	Up-regulation
AGC_PKC_PKCa_PRKCA_ST	Q05193	DNM1	P17252	PRKCA	S619	R622M	622	Missense	distal	3	no	19.028	17.760	EPSD	ICGC;COSMIC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	Q05193	DNM1	P17252	PRKCA	S774	A770T	770	Missense	distal	-4	no	18.929	18.180	EPSD	ICGC;COSMIC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	Q05193	DNM1	P17252	PRKCA	S774	A770D	770	Missense	distal	-4	no	18.929	18.163	EPSD	ICGC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	Q05193	DNM1	P17252	PRKCA	S774	G771E	771	Missense	distal	-3	no	18.929	17.252	EPSD	ICGC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	Q05193	DNM1	P17252	PRKCA	S857	E856Q	856	Missense	proximal	-1	no	20.368	19.919	EPSD	ICGC;COSMIC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	Q05193	DNM1	P17252	PRKCA	S857	P861H	861	Missense	distal	4	no	20.368	20.532	EPSD	ICGC;COSMIC	16.704	Up-regulation
AGC_PKC_PKCa_PRKCA_ST	Q05193	DNM1	P17252	PRKCA	S857	R854S	854	Missense	distal	-3	no	20.368	17.498	EPSD	ICGC;COSMIC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	Q05193	DNM1	P17252	PRKCA	S857	D863N	863	Missense	distal	6	no	20.368	20.283	EPSD	ICGC;COSMIC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	P04049	RAF1	P17252	PRKCA	S43	R40C	40	Missense	distal	-3	no	19.600	16.860	EPSD;PhosphoSitePlus	ICGC;COSMIC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	P04049	RAF1	P17252	PRKCA	S43	R41Q	41	Missense	proximal	-2	no	19.600	17.841	EPSD;PhosphoSitePlus	ICGC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	P04049	RAF1	P17252	PRKCA	T213	S211Y	211	Missense	proximal	-2	no	17.244	17.818	EPSD	ICGC	16.704	Up-regulation
AGC_PKC_PKCa_PRKCA_ST	P04049	RAF1	P17252	PRKCA	T213	S220C	220	Missense	distal	7	no	17.244	17.067	EPSD	ICGC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	P04049	RAF1	P17252	PRKCA	T213	R218L	218	Missense	distal	5	no	17.244	16.912	EPSD	ICGC;COSMIC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	P04049	RAF1	P17252	PRKCA	T213	P207T	207	Missense	distal	-6	no	17.244	17.150	EPSD	ICGC;COSMIC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	P04049	RAF1	P17252	PRKCA	S220	V226D	226	Missense	distal	6	no	19.272	19.343	EPSD	ICGC;COSMIC	16.704	Up-regulation
AGC_PKC_PKCa_PRKCA_ST	P04049	RAF1	P17252	PRKCA	S220	M224I	224	Missense	distal	4	no	19.272	17.777	EPSD	ICGC;COSMIC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	P04049	RAF1	P17252	PRKCA	S220	S220C	220	Missense	central	0	yes	19.272	0.000	EPSD	ICGC	16.704	Loss
AGC_PKC_PKCa_PRKCA_ST	P04049	RAF1	P17252	PRKCA	S220	R218L	218	Missense	proximal	-2	no	19.272	16.584	EPSD	ICGC;COSMIC	16.704	Loss
AGC_PKC_PKCa_PRKCA_ST	P23975	SLC6A2	P17252	PRKCA	S203	T208A	208	Missense	distal	5	no	16.698	16.977	EPSD	ICGC;COSMIC	16.704	Gain
AGC_PKC_PKCa_PRKCA_ST	P23975	SLC6A2	P17252	PRKCA	S259	S259P	259	Missense	central	0	yes	17.416	0.000	EPSD;PhosphoSitePlus	ICGC;COSMIC	16.704	Loss
AGC_PKC_PKCa_PRKCA_ST	P23975	SLC6A2	P17252	PRKCA	S259	G255V	255	Missense	distal	-4	no	17.416	16.853	EPSD;PhosphoSitePlus	ICGC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	P23975	SLC6A2	P17252	PRKCA	S259	W264C	264	Missense	distal	5	no	17.416	17.192	EPSD;PhosphoSitePlus	ICGC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	O94806	PRKD3	P17252	PRKCA	S9	P7A	7	Missense	proximal	-2	no	18.875	18.831	EPSD	ICGC;COSMIC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	O94806	PRKD3	P17252	PRKCA	S9	A10V	10	Missense	proximal	1	no	18.875	19.028	EPSD	ICGC	16.704	Up-regulation
AGC_PKC_PKCa_PRKCA_ST	O94806	PRKD3	P17252	PRKCA	S13	P7A	7	Missense	distal	-6	no	17.886	17.880	EPSD	ICGC;COSMIC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	O94806	PRKD3	P17252	PRKCA	S13	A10V	10	Missense	distal	-3	no	17.886	18.645	EPSD	ICGC	16.704	Up-regulation
AGC_PKC_PKCa_PRKCA_ST	O94806	PRKD3	P17252	PRKCA	S31	P28L	28	Missense	distal	-3	no	18.670	18.163	EPSD	ICGC;COSMIC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	O94806	PRKD3	P17252	PRKCA	S31	P32T	32	Missense	proximal	1	no	18.670	18.598	EPSD	ICGC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	O94806	PRKD3	P17252	PRKCA	S31	L36I	36	Missense	distal	5	no	18.670	18.667	EPSD	ICGC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	O94806	PRKD3	P17252	PRKCA	S37	P32T	32	Missense	distal	-5	no	18.465	18.467	EPSD	ICGC	16.704	Up-regulation
AGC_PKC_PKCa_PRKCA_ST	O94806	PRKD3	P17252	PRKCA	S37	S44R	44	Missense	distal	7	no	18.465	18.511	EPSD	ICGC	16.704	Up-regulation
AGC_PKC_PKCa_PRKCA_ST	O94806	PRKD3	P17252	PRKCA	S37	L36I	36	Missense	proximal	-1	no	18.465	17.601	EPSD	ICGC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	O94806	PRKD3	P17252	PRKCA	S41	S44R	44	Missense	distal	3	no	16.476	17.867	EPSD	ICGC	16.704	Gain
AGC_PKC_PKCa_PRKCA_ST	O94806	PRKD3	P17252	PRKCA	S247	P246T	246	Missense	proximal	-1	no	17.954	17.875	EPSD	ICGC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	O94806	PRKD3	P17252	PRKCA	S247	H243Q	243	Missense	distal	-4	no	17.954	18.151	EPSD	ICGC;COSMIC	16.704	Up-regulation
AGC_PKC_PKCa_PRKCA_ST	O94806	PRKD3	P17252	PRKCA	S247	K248R	248	Missense	proximal	1	no	17.954	17.917	EPSD	ICGC;COSMIC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	O94806	PRKD3	P17252	PRKCA	S247	Q244K	244	Missense	distal	-3	no	17.954	18.785	EPSD	ICGC;COSMIC	16.704	Up-regulation
AGC_PKC_PKCa_PRKCA_ST	O94806	PRKD3	P17252	PRKCA	S252	P246T	246	Missense	distal	-6	no	19.862	19.768	EPSD	ICGC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	O94806	PRKD3	P17252	PRKCA	S252	K248R	248	Missense	distal	-4	no	19.862	19.827	EPSD	ICGC;COSMIC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	O94806	PRKD3	P17252	PRKCA	S406	H409N	409	Missense	distal	3	no	21.892	21.034	EPSD	ICGC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	O94806	PRKD3	P17252	PRKCA	S414	S415R	415	Missense	proximal	1	no	16.415	17.589	EPSD	ICGC	16.704	Gain
AGC_PKC_PKCa_PRKCA_ST	O94806	PRKD3	P17252	PRKCA	S415	H409N	409	Missense	distal	-6	no	18.899	18.836	EPSD	ICGC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	O94806	PRKD3	P17252	PRKCA	S415	S415R	415	Missense	central	0	yes	18.899	0.000	EPSD	ICGC	16.704	Loss
AGC_PKC_PKCa_PRKCA_ST	O94806	PRKD3	P17252	PRKCA	S470	N476K	476	Missense	distal	6	no	19.758	19.920	EPSD	ICGC	16.704	Up-regulation
AGC_PKC_PKCa_PRKCA_ST	O94806	PRKD3	P17252	PRKCA	S470	R472L	472	Missense	proximal	2	no	19.758	14.771	EPSD	ICGC;COSMIC	16.704	Loss
AGC_PKC_PKCa_PRKCA_ST	O94806	PRKD3	P17252	PRKCA	S470	L466F	466	Missense	distal	-4	no	19.758	20.131	EPSD	ICGC;COSMIC	16.704	Up-regulation
AGC_PKC_PKCa_PRKCA_ST	O94806	PRKD3	P17252	PRKCA	S802	E804K	804	Missense	proximal	2	no	11.694	16.974	EPSD	ICGC	16.704	Gain
AGC_PKC_PKCa_PRKCA_ST	O94806	PRKD3	P17252	PRKCA	S822	L827V	827	Missense	distal	5	no	20.749	20.658	EPSD	ICGC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	P10275	AR	P17252	PRKCA	S16	A22S	22	Missense	distal	6	no	18.915	18.886	EPSD	ICGC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	P10275	AR	P17252	PRKCA	S16	V10G	10	Missense	distal	-6	no	18.915	18.995	EPSD	ICGC;COSMIC	16.704	Up-regulation
AGC_PKC_PKCa_PRKCA_ST	P10275	AR	P17252	PRKCA	S16	P12T	12	Missense	distal	-4	no	18.915	18.425	EPSD	ICGC;COSMIC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	P10275	AR	P17252	PRKCA	T18	A22S	22	Missense	distal	4	no	19.880	19.864	EPSD	ICGC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	P10275	AR	P17252	PRKCA	T18	P12T	12	Missense	distal	-6	no	19.880	19.786	EPSD	ICGC;COSMIC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	P10275	AR	P17252	PRKCA	S29	Q35E	35	Missense	distal	6	no	16.872	16.888	EPSD	ICGC;COSMIC	16.704	Up-regulation
AGC_PKC_PKCa_PRKCA_ST	P10275	AR	P17252	PRKCA	S29	R31S	31	Missense	proximal	2	no	16.872	12.252	EPSD	ICGC;COSMIC	16.704	Loss
AGC_PKC_PKCa_PRKCA_ST	P10275	AR	P17252	PRKCA	S29	A22S	22	Missense	distal	-7	no	16.872	16.870	EPSD	ICGC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	P10275	AR	P17252	PRKCA	S208	E204K	204	Missense	distal	-4	no	18.352	19.083	EPSD	ICGC	16.704	Up-regulation
AGC_PKC_PKCa_PRKCA_ST	P10275	AR	P17252	PRKCA	S579	K581N	581	Missense	proximal	2	no	17.121	12.172	PhosphoSitePlus	ICGC;COSMIC	16.704	Loss
AGC_PKC_PKCa_PRKCA_ST	P10275	AR	P17252	PRKCA	S579	L575P	575	Missense	distal	-4	no	17.121	17.380	PhosphoSitePlus	ICGC;COSMIC	16.704	Up-regulation
AGC_PKC_PKCa_PRKCA_ST	P10415	BCL2	P17252	PRKCA	S24	E29D	29	Missense	distal	5	no	20.144	20.052	EPSD	ICGC;COSMIC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	P10415	BCL2	P17252	PRKCA	S24	H20Q	20	Missense	distal	-4	no	20.144	20.341	EPSD	ICGC;COSMIC	16.704	Up-regulation
AGC_PKC_PKCa_PRKCA_ST	P10415	BCL2	P17252	PRKCA	S24	D31G	31	Missense	distal	7	no	20.144	20.163	EPSD	ICGC;COSMIC	16.704	Up-regulation
AGC_PKC_PKCa_PRKCA_ST	P10415	BCL2	P17252	PRKCA	S24	D31E	31	Missense	distal	7	no	20.144	20.092	EPSD	ICGC;COSMIC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	P10415	BCL2	P17252	PRKCA	S24	D31H	31	Missense	distal	7	no	20.144	20.116	EPSD	ICGC;COSMIC;GDSC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	P10415	BCL2	P17252	PRKCA	S24	K22R	22	Missense	proximal	-2	no	20.144	21.771	EPSD	ICGC;COSMIC	16.704	Up-regulation
AGC_PKC_PKCa_PRKCA_ST	P10415	BCL2	P17252	PRKCA	S24	E29K	29	Missense	distal	5	no	20.144	20.558	EPSD	ICGC;COSMIC	16.704	Up-regulation
AGC_PKC_PKCa_PRKCA_ST	P10415	BCL2	P17252	PRKCA	S24	Y21S	21	Missense	distal	-3	no	20.144	21.834	EPSD	ICGC;COSMIC	16.704	Up-regulation
AGC_PKC_PKCa_PRKCA_ST	P00749	PLAU	P17252	PRKCA	S341	P348T	348	Missense	distal	7	no	18.203	18.174	EPSD	ICGC;COSMIC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	P13569	CFTR	P17252	PRKCA	T421	S422F	422	Missense	proximal	1	no	15.280	16.764	EPSD	ICGC;COSMIC	16.704	Gain
AGC_PKC_PKCa_PRKCA_ST	P13569	CFTR	P17252	PRKCA	T604	E608K	608	Missense	distal	4	no	16.282	16.821	EPSD	ICGC;COSMIC	16.704	Gain
AGC_PKC_PKCa_PRKCA_ST	P13569	CFTR	P17252	PRKCA	S641	D648N	648	Missense	distal	7	no	17.253	17.227	EPSD	ICGC;COSMIC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	P13569	CFTR	P17252	PRKCA	S660	E664K	664	Missense	distal	4	no	19.706	20.245	EPSD;PhosphoSitePlus	ICGC	16.704	Up-regulation
AGC_PKC_PKCa_PRKCA_ST	P13569	CFTR	P17252	PRKCA	S670	E664K	664	Missense	distal	-6	no	16.686	16.753	EPSD	ICGC	16.704	Gain
AGC_PKC_PKCa_PRKCA_ST	P13569	CFTR	P17252	PRKCA	S700	E695G	695	Missense	distal	-5	no	18.593	18.610	EPSD	ICGC;COSMIC	16.704	Up-regulation
AGC_PKC_PKCa_PRKCA_ST	P13569	CFTR	P17252	PRKCA	S707	I708V	708	Missense	proximal	1	no	19.036	18.325	EPSD	ICGC;COSMIC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	P13569	CFTR	P17252	PRKCA	S768	R764L	764	Missense	distal	-4	no	19.597	18.972	EPSD	ICGC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	P13569	CFTR	P17252	PRKCA	S790	V794F	794	Missense	distal	4	no	18.923	19.883	EPSD	ICGC	16.704	Up-regulation
AGC_PKC_PKCa_PRKCA_ST	P13569	CFTR	P17252	PRKCA	S790	V794A	794	Missense	distal	4	no	18.923	20.260	EPSD	ICGC	16.704	Up-regulation
AGC_PKC_PKCa_PRKCA_ST	P13569	CFTR	P17252	PRKCA	S795	V794F	794	Missense	proximal	-1	no	16.283	17.038	EPSD;PhosphoSitePlus	ICGC	16.704	Gain
AGC_PKC_PKCa_PRKCA_ST	P13569	CFTR	P17252	PRKCA	S795	V794A	794	Missense	proximal	-1	no	16.283	17.186	EPSD;PhosphoSitePlus	ICGC	16.704	Gain
AGC_PKC_PKCa_PRKCA_ST	P13569	CFTR	P17252	PRKCA	S1248	L1243F	1243	Missense	distal	-5	no	21.308	21.112	EPSD	ICGC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	Q15172	PPP2R5A	P17252	PRKCA	S2	S5P	5	Missense	distal	3	no	17.465	17.325	EPSD	ICGC;GDSC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	Q15172	PPP2R5A	P17252	PRKCA	S28	D22G	22	Missense	distal	-6	no	24.450	24.500	EPSD	ICGC;COSMIC	16.704	Up-regulation
AGC_PKC_PKCa_PRKCA_ST	Q15172	PPP2R5A	P17252	PRKCA	S28	D22H	22	Missense	distal	-6	no	24.450	24.540	EPSD	ICGC	16.704	Up-regulation
AGC_PKC_PKCa_PRKCA_ST	Q15172	PPP2R5A	P17252	PRKCA	S38	S41L	41	Missense	distal	3	no	18.411	17.564	EPSD	ICGC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	Q15172	PPP2R5A	P17252	PRKCA	S38	R37L	37	Missense	proximal	-1	no	18.411	17.604	EPSD	ICGC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	Q15172	PPP2R5A	P17252	PRKCA	S41	S41L	41	Missense	central	0	yes	17.700	0.000	PhosphoSitePlus	ICGC	16.704	Loss
AGC_PKC_PKCa_PRKCA_ST	Q15172	PPP2R5A	P17252	PRKCA	S41	R37L	37	Missense	distal	-4	no	17.700	17.076	PhosphoSitePlus	ICGC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	Q15172	PPP2R5A	P17252	PRKCA	S42	S41L	41	Missense	proximal	-1	no	16.842	16.422	EPSD	ICGC	16.704	Loss
AGC_PKC_PKCa_PRKCA_ST	Q15172	PPP2R5A	P17252	PRKCA	S42	R37L	37	Missense	distal	-5	no	16.842	16.714	EPSD	ICGC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	Q15172	PPP2R5A	P17252	PRKCA	T281	F288L	288	Missense	distal	7	no	17.530	17.596	EPSD	ICGC;COSMIC	16.704	Up-regulation
AGC_PKC_PKCa_PRKCA_ST	Q9Y624	F11R	P17252	PRKCA	S274	K271N	271	Missense	distal	-3	no	18.112	15.911	EPSD	ICGC	16.704	Loss
AGC_PKC_PKCa_PRKCA_ST	Q9Y624	F11R	P17252	PRKCA	S284	P283H	283	Missense	proximal	-1	no	18.239	18.603	PhosphoSitePlus	ICGC;COSMIC	16.704	Up-regulation
AGC_PKC_PKCa_PRKCA_ST	Q9UBS0	RPS6KB2	P17252	PRKCA	T11	E13K	13	Missense	proximal	2	no	11.642	16.921	EPSD	ICGC	16.704	Gain
AGC_PKC_PKCa_PRKCA_ST	Q9UBS0	RPS6KB2	P17252	PRKCA	S219	V225I	225	Missense	distal	6	no	17.293	17.347	EPSD	ICGC;COSMIC	16.704	Up-regulation
AGC_PKC_PKCa_PRKCA_ST	Q9UBS0	RPS6KB2	P17252	PRKCA	S219	C216G	216	Missense	distal	-3	no	17.293	16.770	EPSD	ICGC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	Q9UBS0	RPS6KB2	P17252	PRKCA	S410	F404L	404	Missense	distal	-6	no	21.803	21.823	EPSD	ICGC	16.704	Up-regulation
AGC_PKC_PKCa_PRKCA_ST	Q9UBS0	RPS6KB2	P17252	PRKCA	S416	V422I	422	Missense	distal	6	no	20.048	20.103	EPSD	ICGC;COSMIC;CCLE	16.704	Up-regulation
AGC_PKC_PKCa_PRKCA_ST	Q9UBS0	RPS6KB2	P17252	PRKCA	S416	A420V	420	Missense	distal	4	no	20.048	18.710	EPSD	ICGC;COSMIC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	Q9UBS0	RPS6KB2	P17252	PRKCA	S417	V422I	422	Missense	distal	5	no	18.341	18.428	EPSD	ICGC;COSMIC;CCLE	16.704	Up-regulation
AGC_PKC_PKCa_PRKCA_ST	Q9UBS0	RPS6KB2	P17252	PRKCA	S417	A420V	420	Missense	distal	3	no	18.341	18.085	EPSD	ICGC;COSMIC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	Q13303	KCNAB2	P17252	PRKCA	S14	R16W	16	Missense	proximal	2	no	20.870	15.430	EPSD	ICGC;COSMIC;GDSC;CCLE	16.704	Loss
AGC_PKC_PKCa_PRKCA_ST	Q13303	KCNAB2	P17252	PRKCA	S14	S14L	14	Missense	central	0	yes	20.870	0.000	EPSD	ICGC;COSMIC	16.704	Loss
AGC_PKC_PKCa_PRKCA_ST	Q13303	KCNAB2	P17252	PRKCA	S14	S20A	20	Missense	distal	6	no	20.870	20.899	EPSD	ICGC;COSMIC	16.704	Up-regulation
AGC_PKC_PKCa_PRKCA_ST	Q13303	KCNAB2	P17252	PRKCA	S14	G19V	19	Missense	distal	5	no	20.870	20.729	EPSD	ICGC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	Q13303	KCNAB2	P17252	PRKCA	S14	S20F	20	Missense	distal	6	no	20.870	20.829	EPSD	ICGC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	Q13303	KCNAB2	P17252	PRKCA	S14	R12Q	12	Missense	proximal	-2	no	20.870	19.111	EPSD	ICGC;COSMIC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	Q13303	KCNAB2	P17252	PRKCA	S14	T18M	18	Missense	distal	4	no	20.870	21.351	EPSD	ICGC;COSMIC;CCLE	16.704	Up-regulation
AGC_PKC_PKCa_PRKCA_ST	Q13303	KCNAB2	P17252	PRKCA	S20	G22R	22	Missense	proximal	2	no	15.999	21.244	EPSD	ICGC;COSMIC	16.704	Gain
AGC_PKC_PKCa_PRKCA_ST	Q13303	KCNAB2	P17252	PRKCA	S20	T18M	18	Missense	proximal	-2	no	15.999	16.911	EPSD	ICGC;COSMIC;CCLE	16.704	Gain
AGC_PKC_PKCa_PRKCA_ST	Q13303	KCNAB2	P17252	PRKCA	S26	G22R	22	Missense	distal	-4	no	16.621	16.723	EPSD	ICGC;COSMIC	16.704	Gain
AGC_PKC_PKCa_PRKCA_ST	Q13303	KCNAB2	P17252	PRKCA	S31	S31C	31	Missense	central	0	yes	22.857	0.000	EPSD	ICGC;COSMIC	16.704	Loss
AGC_PKC_PKCa_PRKCA_ST	Q13303	KCNAB2	P17252	PRKCA	S31	R34T	34	Missense	distal	3	no	22.857	21.021	EPSD	ICGC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	Q13303	KCNAB2	P17252	PRKCA	S31	R28L	28	Missense	distal	-3	no	22.857	18.502	EPSD	ICGC;COSMIC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	Q13303	KCNAB2	P17252	PRKCA	S31	R34L	34	Missense	distal	3	no	22.857	20.620	EPSD	ICGC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	Q13303	KCNAB2	P17252	PRKCA	S31	G30W	30	Missense	proximal	-1	no	22.857	21.412	EPSD	ICGC;COSMIC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	Q13303	KCNAB2	P17252	PRKCA	S31	R34Q	34	Missense	distal	3	no	22.857	20.404	EPSD	ICGC;COSMIC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	Q13303	KCNAB2	P17252	PRKCA	S31	R34W	34	Missense	distal	3	no	22.857	19.924	EPSD	ICGC;COSMIC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	P21399	ACO1	P17252	PRKCA	S138	R134I	134	Missense	distal	-4	no	20.036	19.401	EPSD;PhosphoSitePlus	ICGC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	P21399	ACO1	P17252	PRKCA	S138	L145M	145	Missense	distal	7	no	20.036	20.044	EPSD;PhosphoSitePlus	ICGC;COSMIC	16.704	Up-regulation
AGC_PKC_PKCa_PRKCA_ST	P21399	ACO1	P17252	PRKCA	T702	Y709C	709	Missense	distal	7	no	20.388	20.217	EPSD	ICGC;COSMIC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	P21399	ACO1	P17252	PRKCA	T702	R704L	704	Missense	proximal	2	no	20.388	15.401	EPSD	ICGC;COSMIC	16.704	Loss
AGC_PKC_PKCa_PRKCA_ST	P21399	ACO1	P17252	PRKCA	S711	A717S	717	Missense	distal	6	no	19.899	19.869	PhosphoSitePlus;EPSD	ICGC;COSMIC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	P21399	ACO1	P17252	PRKCA	S711	Y709C	709	Missense	proximal	-2	no	19.899	20.927	PhosphoSitePlus;EPSD	ICGC;COSMIC	16.704	Up-regulation
AGC_PKC_PKCa_PRKCA_ST	P21399	ACO1	P17252	PRKCA	S711	R704L	704	Missense	distal	-7	no	19.899	19.888	PhosphoSitePlus;EPSD	ICGC;COSMIC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	P21399	ACO1	P17252	PRKCA	S778	R780L	780	Missense	proximal	2	no	17.767	12.780	EPSD	ICGC	16.704	Loss
AGC_PKC_PKCa_PRKCA_ST	P21731	TBXA2R	P17252	PRKCA	S6	S7F	7	Missense	proximal	1	no	15.570	17.053	EPSD	ICGC	16.704	Gain
AGC_PKC_PKCa_PRKCA_ST	P21731	TBXA2R	P17252	PRKCA	S128	E129Q	129	Missense	proximal	1	no	17.295	18.744	EPSD	ICGC	16.704	Up-regulation
AGC_PKC_PKCa_PRKCA_ST	P21731	TBXA2R	P17252	PRKCA	S145	F138L	138	Missense	distal	-7	no	18.398	18.400	PhosphoSitePlus;EPSD	ICGC;COSMIC	16.704	Up-regulation
AGC_PKC_PKCa_PRKCA_ST	P21731	TBXA2R	P17252	PRKCA	S145	A151T	151	Missense	distal	6	no	18.398	18.320	PhosphoSitePlus;EPSD	ICGC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	P21731	TBXA2R	P17252	PRKCA	S239	M244T	244	Missense	distal	5	no	17.087	16.784	EPSD	ICGC;COSMIC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	P21731	TBXA2R	P17252	PRKCA	S239	S239Y	239	Missense	central	0	yes	17.087	0.000	EPSD	ICGC	16.704	Loss
AGC_PKC_PKCa_PRKCA_ST	P21731	TBXA2R	P17252	PRKCA	S239	R237G	237	Missense	proximal	-2	no	17.087	14.215	EPSD	ICGC;COSMIC	16.704	Loss
AGC_PKC_PKCa_PRKCA_ST	P21731	TBXA2R	P17252	PRKCA	S239	R235H	235	Missense	distal	-4	no	17.087	16.512	EPSD	ICGC;COSMIC	16.704	Loss
AGC_PKC_PKCa_PRKCA_ST	P21731	TBXA2R	P17252	PRKCA	S239	E242K	242	Missense	distal	3	no	17.087	17.703	EPSD	ICGC;COSMIC	16.704	Up-regulation
AGC_PKC_PKCa_PRKCA_ST	P21731	TBXA2R	P17252	PRKCA	S324	L319H	319	Missense	distal	-5	no	18.282	18.054	EPSD;PhosphoSitePlus	ICGC;COSMIC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	P21731	TBXA2R	P17252	PRKCA	S324	S331F	331	Missense	distal	7	no	18.282	18.218	EPSD;PhosphoSitePlus	ICGC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	P21731	TBXA2R	P17252	PRKCA	S324	P327S	327	Missense	distal	3	no	18.282	18.422	EPSD;PhosphoSitePlus	ICGC	16.704	Up-regulation
AGC_PKC_PKCa_PRKCA_ST	P21731	TBXA2R	P17252	PRKCA	S331	Q333K	333	Missense	proximal	2	no	14.881	18.294	EPSD;PhosphoSitePlus	ICGC	16.704	Gain
AGC_PKC_PKCa_PRKCA_ST	P06213	INSR	P17252	PRKCA	S98	D101E	101	Missense	distal	3	no	18.927	19.414	EPSD	ICGC	16.704	Up-regulation
AGC_PKC_PKCa_PRKCA_ST	P06213	INSR	P17252	PRKCA	S407	F409L	409	Missense	proximal	2	no	17.583	16.899	EPSD	ICGC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	P06213	INSR	P17252	PRKCA	S1064	S1064L	1064	Missense	central	0	yes	17.717	0.000	PhosphoSitePlus;EPSD	ICGC	16.704	Loss
AGC_PKC_PKCa_PRKCA_ST	Q02156	PRKCE	P17252	PRKCA	S234	P229L	229	Missense	distal	-5	no	19.631	19.605	EPSD;PhosphoSitePlus	ICGC;COSMIC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	Q96PY5	FMNL2	P17252	PRKCA	S9	R15M	15	Missense	distal	6	no	19.474	19.402	EPSD	ICGC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	Q96PY5	FMNL2	P17252	PRKCA	S171	W168R	168	Missense	distal	-3	no	16.244	18.598	EPSD	ICGC;COSMIC	16.704	Gain
AGC_PKC_PKCa_PRKCA_ST	Q96PY5	FMNL2	P17252	PRKCA	S205	K210N	210	Missense	distal	5	no	17.694	17.188	EPSD	ICGC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	Q96PY5	FMNL2	P17252	PRKCA	S205	S205N	205	Missense	central	0	yes	17.694	0.000	EPSD	ICGC;COSMIC;GDSC;CCLE	16.704	Loss
AGC_PKC_PKCa_PRKCA_ST	Q96PY5	FMNL2	P17252	PRKCA	S205	P204L	204	Missense	proximal	-1	no	17.694	17.574	EPSD	ICGC;COSMIC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	Q96PY5	FMNL2	P17252	PRKCA	S205	R206K	206	Missense	proximal	1	no	17.694	17.731	EPSD	ICGC;COSMIC	16.704	Up-regulation
AGC_PKC_PKCa_PRKCA_ST	Q96PY5	FMNL2	P17252	PRKCA	S216	K210N	210	Missense	distal	-6	no	21.073	20.949	EPSD	ICGC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	Q96PY5	FMNL2	P17252	PRKCA	S216	V215I	215	Missense	proximal	-1	no	21.073	21.252	EPSD	ICGC;COSMIC	16.704	Up-regulation
AGC_PKC_PKCa_PRKCA_ST	Q96PY5	FMNL2	P17252	PRKCA	T450	R452I	452	Missense	proximal	2	no	16.916	11.884	EPSD	ICGC;COSMIC	16.704	Loss
AGC_PKC_PKCa_PRKCA_ST	Q96PY5	FMNL2	P17252	PRKCA	T450	E457D	457	Missense	distal	7	no	16.916	16.968	EPSD	ICGC;COSMIC	16.704	Up-regulation
AGC_PKC_PKCa_PRKCA_ST	Q96PY5	FMNL2	P17252	PRKCA	S466	T467S	467	Missense	proximal	1	no	18.167	17.841	EPSD	ICGC;COSMIC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	P35398	RORA	P17252	PRKCA	S35	Q33K	33	Missense	proximal	-2	no	20.494	20.625	PhosphoSitePlus;EPSD	ICGC	16.704	Up-regulation
AGC_PKC_PKCa_PRKCA_ST	P35398	RORA	P17252	PRKCA	S35	E40K	40	Missense	distal	5	no	20.494	20.908	PhosphoSitePlus;EPSD	ICGC	16.704	Up-regulation
AGC_PKC_PKCa_PRKCA_ST	P35398	RORA	P17252	PRKCA	S35	E28K	28	Missense	distal	-7	no	20.494	20.502	PhosphoSitePlus;EPSD	ICGC	16.704	Up-regulation
AGC_PKC_PKCa_PRKCA_ST	P35398	RORA	P17252	PRKCA	S35	N32Y	32	Missense	distal	-3	no	20.494	20.161	PhosphoSitePlus;EPSD	ICGC;COSMIC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	P35398	RORA	P17252	PRKCA	S49	S51R	51	Missense	proximal	2	no	18.128	22.748	EPSD	ICGC;COSMIC	16.704	Up-regulation
AGC_PKC_PKCa_PRKCA_ST	P35398	RORA	P17252	PRKCA	S49	S51N	51	Missense	proximal	2	no	18.128	17.377	EPSD	ICGC;COSMIC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	Q05940	SLC18A2	P17252	PRKCA	S18	I25F	25	Missense	distal	7	no	20.856	20.945	PhosphoSitePlus;EPSD	ICGC;COSMIC	16.704	Up-regulation
AGC_PKC_PKCa_PRKCA_ST	Q05940	SLC18A2	P17252	PRKCA	S50	Y47F	47	Missense	distal	-3	no	18.249	20.189	EPSD	ICGC;COSMIC	16.704	Up-regulation
AGC_PKC_PKCa_PRKCA_ST	Q05940	SLC18A2	P17252	PRKCA	S50	K52R	52	Missense	proximal	2	no	18.249	18.671	EPSD	ICGC	16.704	Up-regulation
AGC_PKC_PKCa_PRKCA_ST	Q05940	SLC18A2	P17252	PRKCA	S279	P272S	272	Missense	distal	-7	no	21.202	21.205	EPSD	ICGC;COSMIC	16.704	Up-regulation
AGC_PKC_PKCa_PRKCA_ST	Q05940	SLC18A2	P17252	PRKCA	S279	K281N	281	Missense	proximal	2	no	21.202	16.253	EPSD	ICGC;COSMIC	16.704	Loss
AGC_PKC_PKCa_PRKCA_ST	P35612	ADD2	P17252	PRKCA	S62	E65Q	65	Missense	distal	3	no	18.890	17.675	EPSD	ICGC;COSMIC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	P35612	ADD2	P17252	PRKCA	S62	E66K	66	Missense	distal	4	no	18.890	19.429	EPSD	ICGC	16.704	Up-regulation
AGC_PKC_PKCa_PRKCA_ST	P35612	ADD2	P17252	PRKCA	S62	M56V	56	Missense	distal	-6	no	18.890	18.780	EPSD	ICGC;COSMIC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	P35612	ADD2	P17252	PRKCA	S62	L58Q	58	Missense	distal	-4	no	18.890	19.137	EPSD	ICGC;COSMIC	16.704	Up-regulation
AGC_PKC_PKCa_PRKCA_ST	P35612	ADD2	P17252	PRKCA	S455	T461M	461	Missense	distal	6	no	19.179	19.226	EPSD	ICGC;COSMIC	16.704	Up-regulation
AGC_PKC_PKCa_PRKCA_ST	P35612	ADD2	P17252	PRKCA	S455	P458H	458	Missense	distal	3	no	19.179	19.998	EPSD	ICGC;COSMIC	16.704	Up-regulation
AGC_PKC_PKCa_PRKCA_ST	P35612	ADD2	P17252	PRKCA	S455	S452R	452	Missense	distal	-3	no	19.179	22.048	EPSD	ICGC	16.704	Up-regulation
AGC_PKC_PKCa_PRKCA_ST	P35612	ADD2	P17252	PRKCA	S455	T460N	460	Missense	distal	5	no	19.179	19.133	EPSD	ICGC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	P35612	ADD2	P17252	PRKCA	S539	G541R	541	Missense	proximal	2	no	15.947	21.193	EPSD	ICGC;COSMIC;GDSC;CCLE	16.704	Gain
AGC_PKC_PKCa_PRKCA_ST	P35612	ADD2	P17252	PRKCA	S617	P614R	614	Missense	distal	-3	no	13.306	17.154	EPSD	ICGC	16.704	Gain
AGC_PKC_PKCa_PRKCA_ST	P35612	ADD2	P17252	PRKCA	S703	P698H	698	Missense	distal	-5	no	18.466	18.212	EPSD	ICGC;COSMIC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	P35612	ADD2	P17252	PRKCA	S713	S718I	718	Missense	distal	5	no	18.575	18.381	EPSD;PhosphoSitePlus	ICGC;CCLE	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	P35612	ADD2	P17252	PRKCA	S718	S718I	718	Missense	central	0	yes	19.678	0.000	EPSD	ICGC;CCLE	16.704	Loss
AGC_PKC_PKCa_PRKCA_ST	Q9NRF2	SH2B1	P17252	PRKCA	S25	R27W	27	Missense	proximal	2	no	18.491	13.051	EPSD	ICGC	16.704	Loss
AGC_PKC_PKCa_PRKCA_ST	Q9NRF2	SH2B1	P17252	PRKCA	S25	P22L	22	Missense	distal	-3	no	18.491	17.984	EPSD	ICGC;COSMIC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	Q9NRF2	SH2B1	P17252	PRKCA	S65	R66H	66	Missense	proximal	1	no	16.928	16.115	EPSD	ICGC;COSMIC;GDSC;CCLE	16.704	Loss
AGC_PKC_PKCa_PRKCA_ST	Q9NRF2	SH2B1	P17252	PRKCA	S144	L149I	149	Missense	distal	5	no	19.824	19.821	EPSD	ICGC;COSMIC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	Q9NRF2	SH2B1	P17252	PRKCA	S154	L149I	149	Missense	distal	-5	no	22.641	22.198	EPSD	ICGC;COSMIC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	Q9NRF2	SH2B1	P17252	PRKCA	S161	R167C	167	Missense	distal	6	no	21.126	20.887	PhosphoSitePlus;EPSD	ICGC;COSMIC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	Q9NRF2	SH2B1	P17252	PRKCA	S165	R167C	167	Missense	proximal	2	no	23.313	18.962	EPSD;PhosphoSitePlus	ICGC;COSMIC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	Q9NRF2	SH2B1	P17252	PRKCA	S384	A382S	382	Missense	proximal	-2	no	17.651	17.435	EPSD	ICGC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	Q9H1D0	TRPV6	P17252	PRKCA	S182	R180W	180	Missense	proximal	-2	no	19.957	17.959	EPSD	ICGC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	O95786	DDX58	P17252	PRKCA	S8	R7C	7	Missense	proximal	-1	no	21.758	19.098	PhosphoSitePlus;EPSD	ICGC;COSMIC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	O95786	DDX58	P17252	PRKCA	S8	Q5H	5	Missense	distal	-3	no	21.758	20.759	PhosphoSitePlus;EPSD	ICGC;COSMIC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	P07949	RET	P17252	PRKCA	S6	A8V	8	Missense	proximal	2	no	17.114	16.799	EPSD	ICGC;COSMIC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	P07949	RET	P17252	PRKCA	S159	C157F	157	Missense	proximal	-2	no	18.041	15.767	EPSD	ICGC	16.704	Loss
AGC_PKC_PKCa_PRKCA_ST	P07949	RET	P17252	PRKCA	T675	A680S	680	Missense	distal	5	no	18.261	18.158	PhosphoSitePlus	ICGC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	P07949	RET	P17252	PRKCA	T675	A680T	680	Missense	distal	5	no	18.261	17.982	PhosphoSitePlus	ICGC;COSMIC;GDSC;CCLE	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	P07949	RET	P17252	PRKCA	T675	M674I	674	Missense	proximal	-1	no	18.261	16.318	PhosphoSitePlus	ICGC;COSMIC	16.704	Loss
AGC_PKC_PKCa_PRKCA_ST	P07949	RET	P17252	PRKCA	T675	R677L	677	Missense	proximal	2	no	18.261	13.274	PhosphoSitePlus	ICGC;COSMIC	16.704	Loss
AGC_PKC_PKCa_PRKCA_ST	P07949	RET	P17252	PRKCA	S686	G691S	691	Missense	distal	5	no	16.759	16.899	EPSD	ICGC;COSMIC	16.704	Up-regulation
AGC_PKC_PKCa_PRKCA_ST	P07949	RET	P17252	PRKCA	S686	S686I	686	Missense	central	0	yes	16.759	0.000	EPSD	ICGC	16.704	Loss
AGC_PKC_PKCa_PRKCA_ST	P07949	RET	P17252	PRKCA	S686	A680S	680	Missense	distal	-6	no	16.759	16.796	EPSD	ICGC	16.704	Up-regulation
AGC_PKC_PKCa_PRKCA_ST	P07949	RET	P17252	PRKCA	S686	A680T	680	Missense	distal	-6	no	16.759	16.670	EPSD	ICGC;COSMIC;GDSC;CCLE	16.704	Loss
AGC_PKC_PKCa_PRKCA_ST	P07949	RET	P17252	PRKCA	S696	G691S	691	Missense	distal	-5	no	20.184	20.047	EPSD	ICGC;COSMIC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	P05556	ITGB1	P17252	PRKCA	S61	A62E	62	Missense	proximal	1	no	18.513	17.322	EPSD	ICGC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	P05556	ITGB1	P17252	PRKCA	S61	Q55K	55	Missense	distal	-6	no	18.513	18.649	EPSD	ICGC	16.704	Up-regulation
AGC_PKC_PKCa_PRKCA_ST	P05556	ITGB1	P17252	PRKCA	S61	Q55H	55	Missense	distal	-6	no	18.513	18.589	EPSD	ICGC;COSMIC	16.704	Up-regulation
AGC_PKC_PKCa_PRKCA_ST	O15519	CFLAR	P17252	PRKCA	S193	A189S	189	Missense	distal	-4	no	18.401	18.314	PhosphoSitePlus	ICGC;COSMIC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	O15519	CFLAR	P17252	PRKCA	S193	I190V	190	Missense	distal	-3	no	18.401	19.198	PhosphoSitePlus	ICGC;COSMIC	16.704	Up-regulation
AGC_PKC_PKCa_PRKCA_ST	O15519	CFLAR	P17252	PRKCA	S227	V224M	224	Missense	distal	-3	no	17.283	18.001	EPSD	ICGC;COSMIC	16.704	Up-regulation
AGC_PKC_PKCa_PRKCA_ST	P08670	VIM	P17252	PRKCA	S25	P24L	24	Missense	proximal	-1	no	19.761	19.641	EPSD	ICGC;COSMIC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	P08670	VIM	P17252	PRKCA	S25	V31A	31	Missense	distal	6	no	19.761	19.880	EPSD	ICGC	16.704	Up-regulation
AGC_PKC_PKCa_PRKCA_ST	P08670	VIM	P17252	PRKCA	S26	P24L	24	Missense	proximal	-2	no	23.535	23.889	EPSD	ICGC;COSMIC	16.704	Up-regulation
AGC_PKC_PKCa_PRKCA_ST	P08670	VIM	P17252	PRKCA	S26	V31A	31	Missense	distal	5	no	23.535	23.919	EPSD	ICGC	16.704	Up-regulation
AGC_PKC_PKCa_PRKCA_ST	P08670	VIM	P17252	PRKCA	S34	V31A	31	Missense	distal	-3	no	16.913	16.153	EPSD	ICGC	16.704	Loss
AGC_PKC_PKCa_PRKCA_ST	P08670	VIM	P17252	PRKCA	S34	R36S	36	Missense	proximal	2	no	16.913	12.293	EPSD	ICGC;COSMIC	16.704	Loss
AGC_PKC_PKCa_PRKCA_ST	P08670	VIM	P17252	PRKCA	S42	R45H	45	Missense	distal	3	no	17.403	16.691	EPSD	ICGC	16.704	Loss
AGC_PKC_PKCa_PRKCA_ST	P08670	VIM	P17252	PRKCA	S42	R36S	36	Missense	distal	-6	no	17.403	17.329	EPSD	ICGC;COSMIC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	P08670	VIM	P17252	PRKCA	S47	R45H	45	Missense	proximal	-2	no	16.757	12.203	EPSD	ICGC	16.704	Loss
AGC_PKC_PKCa_PRKCA_ST	P08670	VIM	P17252	PRKCA	S47	A54G	54	Missense	distal	7	no	16.757	16.780	EPSD	ICGC	16.704	Up-regulation
AGC_PKC_PKCa_PRKCA_ST	P08670	VIM	P17252	PRKCA	T48	R45H	45	Missense	distal	-3	no	18.727	14.871	EPSD	ICGC	16.704	Loss
AGC_PKC_PKCa_PRKCA_ST	P08670	VIM	P17252	PRKCA	T48	S55L	55	Missense	distal	7	no	18.727	18.730	EPSD	ICGC	16.704	Up-regulation
AGC_PKC_PKCa_PRKCA_ST	P08670	VIM	P17252	PRKCA	T48	A54G	54	Missense	distal	6	no	18.727	18.620	EPSD	ICGC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	P08670	VIM	P17252	PRKCA	S66	A62V	62	Missense	distal	-4	no	17.139	16.580	EPSD	ICGC	16.704	Loss
AGC_PKC_PKCa_PRKCA_ST	P08670	VIM	P17252	PRKCA	S205	V210I	210	Missense	distal	5	no	17.977	18.065	EPSD	ICGC;COSMIC	16.704	Up-regulation
AGC_PKC_PKCa_PRKCA_ST	P08670	VIM	P17252	PRKCA	S205	R207G	207	Missense	proximal	2	no	17.977	12.732	EPSD	ICGC;COSMIC	16.704	Loss
AGC_PKC_PKCa_PRKCA_ST	P08670	VIM	P17252	PRKCA	S293	E286K	286	Missense	distal	-7	no	17.032	17.040	EPSD	ICGC	16.704	Up-regulation
AGC_PKC_PKCa_PRKCA_ST	Q04637	EIF4G1	P17252	PRKCA	S1145	E1152D	1152	Missense	distal	7	no	20.664	20.716	EPSD	ICGC;COSMIC	16.704	Up-regulation
AGC_PKC_PKCa_PRKCA_ST	Q04637	EIF4G1	P17252	PRKCA	S1164	R1166H	1166	Missense	proximal	2	no	16.751	11.727	EPSD	ICGC;COSMIC	16.704	Loss
AGC_PKC_PKCa_PRKCA_ST	Q04637	EIF4G1	P17252	PRKCA	S1185	R1184Q	1184	Missense	proximal	-1	no	17.449	16.632	PhosphoSitePlus	ICGC;COSMIC	16.704	Loss
AGC_PKC_PKCa_PRKCA_ST	Q04637	EIF4G1	P17252	PRKCA	S1209	E1212Q	1212	Missense	distal	3	no	16.733	15.518	EPSD	ICGC;COSMIC	16.704	Loss
AGC_PKC_PKCa_PRKCA_ST	Q04637	EIF4G1	P17252	PRKCA	S1209	E1202D	1202	Missense	distal	-7	no	16.733	16.736	EPSD	ICGC	16.704	Up-regulation
AGC_PKC_PKCa_PRKCA_ST	P31749	AKT1	P17252	PRKCA	T87	H89R	89	Missense	proximal	2	no	12.072	17.096	EPSD	ICGC	16.704	Gain
AGC_PKC_PKCa_PRKCA_ST	P31749	AKT1	P17252	PRKCA	S246	D248H	248	Missense	proximal	2	no	18.142	18.397	EPSD	ICGC;COSMIC	16.704	Up-regulation
AGC_PKC_PKCa_PRKCA_ST	P31749	AKT1	P17252	PRKCA	S246	A250D	250	Missense	distal	4	no	18.142	17.773	EPSD	ICGC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	P31749	AKT1	P17252	PRKCA	S246	E242K	242	Missense	distal	-4	no	18.142	18.873	EPSD	ICGC	16.704	Up-regulation
AGC_PKC_PKCa_PRKCA_ST	P31749	AKT1	P17252	PRKCA	S246	V244A	244	Missense	proximal	-2	no	18.142	17.898	EPSD	ICGC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	P31749	AKT1	P17252	PRKCA	S246	R249W	249	Missense	distal	3	no	18.142	15.208	EPSD	ICGC;COSMIC	16.704	Loss
AGC_PKC_PKCa_PRKCA_ST	P31749	AKT1	P17252	PRKCA	S246	R251S	251	Missense	distal	5	no	18.142	18.000	EPSD	ICGC;COSMIC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	P31749	AKT1	P17252	PRKCA	S475	S477R	477	Missense	proximal	2	no	12.775	17.395	EPSD	ICGC	16.704	Gain
AGC_PKC_PKCa_PRKCA_ST	Q96A00	PPP1R14A	P17252	PRKCA	S12	R9C	9	Missense	distal	-3	no	18.773	16.033	EPSD	ICGC	16.704	Loss
AGC_PKC_PKCa_PRKCA_ST	Q96A00	PPP1R14A	P17252	PRKCA	S16	R21C	21	Missense	distal	5	no	19.223	18.491	EPSD	ICGC;COSMIC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	Q96A00	PPP1R14A	P17252	PRKCA	S16	R9C	9	Missense	distal	-7	no	19.223	19.204	EPSD	ICGC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	Q96A00	PPP1R14A	P17252	PRKCA	S18	R21C	21	Missense	distal	3	no	16.986	14.368	EPSD	ICGC;COSMIC	16.704	Loss
AGC_PKC_PKCa_PRKCA_ST	P14598	NCF1	P17252	PRKCA	T45	E46K	46	Missense	proximal	1	no	16.111	17.715	EPSD	ICGC	16.704	Gain
AGC_PKC_PKCa_PRKCA_ST	Q86UR1	NOXA1	P17252	PRKCA	S172	R170L	170	Missense	proximal	-2	no	21.123	18.435	PhosphoSitePlus	ICGC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	Q86UR1	NOXA1	P17252	PRKCA	S172	G171V	171	Missense	proximal	-1	no	21.123	19.412	PhosphoSitePlus	ICGC;COSMIC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	Q86UR1	NOXA1	P17252	PRKCA	S172	D165Y	165	Missense	distal	-7	no	21.123	21.127	PhosphoSitePlus	ICGC	16.704	Up-regulation
AGC_PKC_PKCa_PRKCA_ST	Q86UR1	NOXA1	P17252	PRKCA	S172	R176W	176	Missense	distal	4	no	21.123	19.587	PhosphoSitePlus	ICGC;COSMIC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	Q03721	KCNC4	P17252	PRKCA	S8	K14N	14	Missense	distal	6	no	18.348	18.187	EPSD	ICGC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	Q03721	KCNC4	P17252	PRKCA	S9	K14N	14	Missense	distal	5	no	23.446	22.940	EPSD	ICGC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	Q03721	KCNC4	P17252	PRKCA	S15	K14N	14	Missense	proximal	-1	no	19.374	18.772	PhosphoSitePlus;EPSD	ICGC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	Q03721	KCNC4	P17252	PRKCA	T49	T56P	56	Missense	distal	7	no	17.971	18.001	EPSD	ICGC;COSMIC	16.704	Up-regulation
AGC_PKC_PKCa_PRKCA_ST	Q03721	KCNC4	P17252	PRKCA	T49	L54M	54	Missense	distal	5	no	17.971	18.289	EPSD	ICGC;COSMIC	16.704	Up-regulation
AGC_PKC_PKCa_PRKCA_ST	Q03721	KCNC4	P17252	PRKCA	T567	E569K	569	Missense	proximal	2	no	11.652	16.931	EPSD	ICGC;COSMIC;CCLE	16.704	Gain
AGC_PKC_PKCa_PRKCA_ST	Q03721	KCNC4	P17252	PRKCA	S577	E570G	570	Missense	distal	-7	no	17.833	17.837	EPSD	ICGC	16.704	Up-regulation
AGC_PKC_PKCa_PRKCA_ST	Q03721	KCNC4	P17252	PRKCA	S577	R576H	576	Missense	proximal	-1	no	17.833	17.510	EPSD	ICGC;COSMIC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	Q03721	KCNC4	P17252	PRKCA	T578	R576H	576	Missense	proximal	-2	no	21.447	16.894	EPSD	ICGC;COSMIC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	P36897	TGFBR1	P17252	PRKCA	T200	I205S	205	Missense	distal	5	no	16.891	17.085	PhosphoSitePlus	ICGC;COSMIC	16.704	Up-regulation
AGC_PKC_PKCa_PRKCA_ST	P46940	IQGAP1	P17252	PRKCA	S91	V89L	89	Missense	proximal	-2	no	18.228	18.381	EPSD	ICGC	16.704	Up-regulation
AGC_PKC_PKCa_PRKCA_ST	P46940	IQGAP1	P17252	PRKCA	S91	R98L	98	Missense	distal	7	no	18.228	18.184	EPSD	ICGC;COSMIC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	P46940	IQGAP1	P17252	PRKCA	S91	L92Q	92	Missense	proximal	1	no	18.228	18.458	EPSD	ICGC;COSMIC	16.704	Up-regulation
AGC_PKC_PKCa_PRKCA_ST	P46940	IQGAP1	P17252	PRKCA	S280	E283Q	283	Missense	distal	3	no	17.016	15.801	EPSD	ICGC;COSMIC	16.704	Loss
AGC_PKC_PKCa_PRKCA_ST	P46940	IQGAP1	P17252	PRKCA	S360	S360F	360	Missense	central	0	yes	18.760	0.000	EPSD	ICGC;COSMIC	16.704	Loss
AGC_PKC_PKCa_PRKCA_ST	P46940	IQGAP1	P17252	PRKCA	S644	R647H	647	Missense	distal	3	no	17.321	16.609	EPSD	ICGC;COSMIC	16.704	Loss
AGC_PKC_PKCa_PRKCA_ST	P46940	IQGAP1	P17252	PRKCA	S934	L937R	937	Missense	distal	3	no	17.279	19.517	EPSD	ICGC;COSMIC	16.704	Up-regulation
AGC_PKC_PKCa_PRKCA_ST	P46940	IQGAP1	P17252	PRKCA	S1104	E1103D	1103	Missense	proximal	-1	no	18.161	17.648	EPSD	ICGC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	P46940	IQGAP1	P17252	PRKCA	S1104	E1108D	1108	Missense	distal	4	no	18.161	17.931	EPSD	ICGC;COSMIC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	P46940	IQGAP1	P17252	PRKCA	S1133	I1135V	1135	Missense	proximal	2	no	17.028	17.045	EPSD	ICGC;COSMIC	16.704	Up-regulation
AGC_PKC_PKCa_PRKCA_ST	P46940	IQGAP1	P17252	PRKCA	S1227	H1234R	1234	Missense	distal	7	no	17.528	17.599	EPSD	ICGC;COSMIC	16.704	Up-regulation
AGC_PKC_PKCa_PRKCA_ST	P46940	IQGAP1	P17252	PRKCA	S1237	H1234R	1234	Missense	distal	-3	no	15.317	19.174	EPSD	ICGC;COSMIC	16.704	Gain
AGC_PKC_PKCa_PRKCA_ST	P10588	NR2F6	P17252	PRKCA	S83	R86L	86	Missense	distal	3	no	24.511	22.273	PhosphoSitePlus	ICGC;COSMIC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	P10588	NR2F6	P17252	PRKCA	S345	Q342R	342	Missense	distal	-3	no	14.955	17.813	EPSD	ICGC;COSMIC	16.704	Gain
AGC_PKC_PKCa_PRKCA_ST	Q9UH77	KLHL3	P17252	PRKCA	S9	S5I	5	Missense	distal	-4	no	16.900	16.458	EPSD	ICGC;COSMIC	16.704	Loss
AGC_PKC_PKCa_PRKCA_ST	Q9UH77	KLHL3	P17252	PRKCA	S9	Q11K	11	Missense	proximal	2	no	16.900	20.313	EPSD	ICGC;COSMIC	16.704	Up-regulation
AGC_PKC_PKCa_PRKCA_ST	Q9UH77	KLHL3	P17252	PRKCA	S10	S5I	5	Missense	distal	-5	no	17.261	17.117	EPSD	ICGC;COSMIC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	Q9UH77	KLHL3	P17252	PRKCA	S10	S9T	9	Missense	proximal	-1	no	17.261	16.883	EPSD	ICGC;COSMIC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	Q9UH77	KLHL3	P17252	PRKCA	S10	G17W	17	Missense	distal	7	no	17.261	17.105	EPSD	ICGC;COSMIC;CCLE	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	Q9UH77	KLHL3	P17252	PRKCA	S10	Q11K	11	Missense	proximal	1	no	17.261	17.416	EPSD	ICGC;COSMIC	16.704	Up-regulation
AGC_PKC_PKCa_PRKCA_ST	Q9UH77	KLHL3	P17252	PRKCA	S433	V438F	438	Missense	distal	5	no	18.860	19.175	PhosphoSitePlus	ICGC;COSMIC	16.704	Up-regulation
AGC_PKC_PKCa_PRKCA_ST	P11234	RALB	P17252	PRKCA	S50	K47T	47	Missense	distal	-3	no	20.678	18.541	EPSD	ICGC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	Q13522	PPP1R1A	P17252	PRKCA	S6	N5D	5	Missense	proximal	-1	no	19.913	19.575	EPSD	ICGC;COSMIC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	Q13522	PPP1R1A	P17252	PRKCA	T35	R30Q	30	Missense	distal	-5	no	17.620	17.468	EPSD	ICGC;COSMIC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	Q13522	PPP1R1A	P17252	PRKCA	S67	T63I	63	Missense	distal	-4	no	19.017	19.237	PhosphoSitePlus;EPSD	ICGC;COSMIC	16.704	Up-regulation
AGC_PKC_PKCa_PRKCA_ST	Q13522	PPP1R1A	P17252	PRKCA	S67	R69W	69	Missense	proximal	2	no	19.017	13.577	PhosphoSitePlus;EPSD	ICGC;COSMIC	16.704	Loss
AGC_PKC_PKCa_PRKCA_ST	Q13522	PPP1R1A	P17252	PRKCA	S67	S67F	67	Missense	central	0	yes	19.017	0.000	PhosphoSitePlus;EPSD	ICGC;COSMIC	16.704	Loss
AGC_PKC_PKCa_PRKCA_ST	Q9BQE3	TUBA1C	P17252	PRKCA	T82	I75T	75	Missense	distal	-7	no	19.353	19.360	EPSD	ICGC;COSMIC	16.704	Up-regulation
AGC_PKC_PKCa_PRKCA_ST	Q9BQE3	TUBA1C	P17252	PRKCA	S232	L227F	227	Missense	distal	-5	no	17.007	16.811	EPSD	ICGC;COSMIC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	P52566	ARHGDIB	P17252	PRKCA	T2	T2N	2	Missense	central	0	yes	17.817	0.000	EPSD	ICGC	16.704	Loss
AGC_PKC_PKCa_PRKCA_ST	P52566	ARHGDIB	P17252	PRKCA	S31	M38T	38	Missense	distal	7	no	18.603	18.599	PhosphoSitePlus	ICGC;COSMIC;CCLE	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	P52566	ARHGDIB	P17252	PRKCA	S31	P26H	26	Missense	distal	-5	no	18.603	18.349	PhosphoSitePlus	ICGC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	P52566	ARHGDIB	P17252	PRKCA	T129	Q127K	127	Missense	proximal	-2	no	17.120	17.252	EPSD	ICGC;COSMIC	16.704	Up-regulation
AGC_PKC_PKCa_PRKCA_ST	P52566	ARHGDIB	P17252	PRKCA	T129	L123M	123	Missense	distal	-6	no	17.120	17.183	EPSD	ICGC	16.704	Up-regulation
AGC_PKC_PKCa_PRKCA_ST	P52566	ARHGDIB	P17252	PRKCA	S194	S188R	188	Missense	distal	-6	no	18.678	18.752	EPSD	ICGC;COSMIC	16.704	Up-regulation
AGC_PKC_PKCa_PRKCA_ST	P52566	ARHGDIB	P17252	PRKCA	S194	E198G	198	Missense	distal	4	no	18.678	18.443	EPSD	ICGC;COSMIC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	Q15139	PRKD1	P17252	PRKCA	S153	V151G	151	Missense	proximal	-2	no	20.548	20.518	EPSD	ICGC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	Q15139	PRKD1	P17252	PRKCA	S153	H147Y	147	Missense	distal	-6	no	20.548	20.489	EPSD	ICGC;COSMIC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	Q15139	PRKD1	P17252	PRKCA	S153	H152R	152	Missense	proximal	-1	no	20.548	20.871	EPSD	ICGC;COSMIC	16.704	Up-regulation
AGC_PKC_PKCa_PRKCA_ST	Q15139	PRKD1	P17252	PRKCA	S205	R203S	203	Missense	proximal	-2	no	19.048	15.746	EPSD	ICGC;COSMIC	16.704	Loss
AGC_PKC_PKCa_PRKCA_ST	Q15139	PRKD1	P17252	PRKCA	S205	G198S	198	Missense	distal	-7	no	19.048	19.052	EPSD	ICGC;COSMIC	16.704	Up-regulation
AGC_PKC_PKCa_PRKCA_ST	Q15139	PRKD1	P17252	PRKCA	S205	V207F	207	Missense	proximal	2	no	19.048	19.759	EPSD	ICGC;COSMIC	16.704	Up-regulation
AGC_PKC_PKCa_PRKCA_ST	Q15139	PRKD1	P17252	PRKCA	S205	G198C	198	Missense	distal	-7	no	19.048	19.038	EPSD	ICGC;COSMIC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	Q15139	PRKD1	P17252	PRKCA	S412	R418K	418	Missense	distal	6	no	20.971	20.959	EPSD	ICGC;COSMIC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	Q15139	PRKD1	P17252	PRKCA	S420	R418K	418	Missense	proximal	-2	no	17.272	15.644	EPSD	ICGC;COSMIC	16.704	Loss
AGC_PKC_PKCa_PRKCA_ST	Q15139	PRKD1	P17252	PRKCA	S420	M424T	424	Missense	distal	4	no	17.272	16.790	EPSD	ICGC;COSMIC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	Q15139	PRKD1	P17252	PRKCA	S421	R418K	418	Missense	distal	-3	no	18.202	16.176	EPSD	ICGC;COSMIC	16.704	Loss
AGC_PKC_PKCa_PRKCA_ST	Q15139	PRKD1	P17252	PRKCA	S421	M424T	424	Missense	distal	3	no	18.202	17.634	EPSD	ICGC;COSMIC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	Q15139	PRKD1	P17252	PRKCA	S738	R740W	740	Missense	proximal	2	no	20.313	14.873	PhosphoSitePlus;EPSD	ICGC;COSMIC;GDSC;CCLE	16.704	Loss
AGC_PKC_PKCa_PRKCA_ST	Q15139	PRKD1	P17252	PRKCA	S738	R740L	740	Missense	proximal	2	no	20.313	15.326	PhosphoSitePlus;EPSD	ICGC;COSMIC	16.704	Loss
AGC_PKC_PKCa_PRKCA_ST	Q15139	PRKD1	P17252	PRKCA	S742	R740W	740	Missense	proximal	-2	no	19.960	17.963	EPSD;PhosphoSitePlus	ICGC;COSMIC;GDSC;CCLE	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	Q15139	PRKD1	P17252	PRKCA	S742	R740L	740	Missense	proximal	-2	no	19.960	17.272	EPSD;PhosphoSitePlus	ICGC;COSMIC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	Q15139	PRKD1	P17252	PRKCA	S829	V830L	830	Missense	proximal	1	no	19.730	19.605	EPSD	ICGC;COSMIC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	P55087	AQP4	P17252	PRKCA	S180	I174T	174	Missense	distal	-6	no	22.148	22.120	PhosphoSitePlus	ICGC;COSMIC;GDSC;CCLE	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	P55087	AQP4	P17252	PRKCA	S180	G187D	187	Missense	distal	7	no	22.148	22.129	PhosphoSitePlus	ICGC;COSMIC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	P55087	AQP4	P17252	PRKCA	S276	M278K	278	Missense	proximal	2	no	13.834	17.860	EPSD	ICGC;COSMIC	16.704	Gain
AGC_PKC_PKCa_PRKCA_ST	P17302	GJA1	P17252	PRKCA	S244	G242R	242	Missense	proximal	-2	no	14.405	17.277	EPSD	ICGC;COSMIC;GDSC	16.704	Gain
AGC_PKC_PKCa_PRKCA_ST	P17302	GJA1	P17252	PRKCA	S296	K303N	303	Missense	distal	7	no	17.041	16.921	EPSD	ICGC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	P17302	GJA1	P17252	PRKCA	S296	D292N	292	Missense	distal	-4	no	17.041	17.390	EPSD	ICGC	16.704	Up-regulation
AGC_PKC_PKCa_PRKCA_ST	P17302	GJA1	P17252	PRKCA	S296	R293I	293	Missense	distal	-3	no	17.041	12.554	EPSD	ICGC	16.704	Loss
AGC_PKC_PKCa_PRKCA_ST	P17302	GJA1	P17252	PRKCA	S296	T290N	290	Missense	distal	-6	no	17.041	17.110	EPSD	ICGC	16.704	Up-regulation
AGC_PKC_PKCa_PRKCA_ST	P17302	GJA1	P17252	PRKCA	S296	T290I	290	Missense	distal	-6	no	17.041	17.070	EPSD	ICGC;COSMIC	16.704	Up-regulation
AGC_PKC_PKCa_PRKCA_ST	P17302	GJA1	P17252	PRKCA	S296	V289L	289	Missense	distal	-7	no	17.041	17.044	EPSD	ICGC;COSMIC	16.704	Up-regulation
AGC_PKC_PKCa_PRKCA_ST	P17302	GJA1	P17252	PRKCA	S344	K345R	345	Missense	proximal	1	no	18.437	18.400	EPSD	ICGC;COSMIC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	P17302	GJA1	P17252	PRKCA	S344	D340A	340	Missense	distal	-4	no	18.437	19.202	EPSD	ICGC	16.704	Up-regulation
AGC_PKC_PKCa_PRKCA_ST	P17302	GJA1	P17252	PRKCA	S364	R362Q	362	Missense	proximal	-2	no	19.138	17.379	EPSD	ICGC;COSMIC;GDSC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	P17302	GJA1	P17252	PRKCA	S364	D360E	360	Missense	distal	-4	no	19.138	19.314	EPSD	ICGC;COSMIC	16.704	Up-regulation
AGC_PKC_PKCa_PRKCA_ST	P17302	GJA1	P17252	PRKCA	S364	R370H	370	Missense	distal	6	no	19.138	19.061	EPSD	ICGC;GDSC;CCLE	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	P17302	GJA1	P17252	PRKCA	S368	R362Q	362	Missense	distal	-6	no	19.498	19.355	EPSD;PhosphoSitePlus	ICGC;COSMIC;GDSC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	P17302	GJA1	P17252	PRKCA	S368	R370H	370	Missense	proximal	2	no	19.498	14.474	EPSD;PhosphoSitePlus	ICGC;GDSC;CCLE	16.704	Loss
AGC_PKC_PKCa_PRKCA_ST	P17302	GJA1	P17252	PRKCA	S372	D378N	378	Missense	distal	6	no	19.465	19.380	PhosphoSitePlus;EPSD	ICGC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	P17302	GJA1	P17252	PRKCA	S372	R370H	370	Missense	proximal	-2	no	19.465	14.911	PhosphoSitePlus;EPSD	ICGC;GDSC;CCLE	16.704	Loss
AGC_PKC_PKCa_PRKCA_ST	P17302	GJA1	P17252	PRKCA	S373	D378N	378	Missense	distal	5	no	16.953	16.952	EPSD	ICGC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	P17302	GJA1	P17252	PRKCA	S373	R370H	370	Missense	distal	-3	no	16.953	13.096	EPSD	ICGC;GDSC;CCLE	16.704	Loss
AGC_PKC_PKCa_PRKCA_ST	P00533	EGFR	P17252	PRKCA	S1162	A1155T	1155	Missense	distal	-7	no	16.914	16.910	EPSD	ICGC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	P00533	EGFR	P17252	PRKCA	S1162	D1168N	1168	Missense	distal	6	no	16.914	16.830	EPSD	ICGC;COSMIC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	P00533	EGFR	P17252	PRKCA	S1162	H1156N	1156	Missense	distal	-6	no	16.914	16.852	EPSD	ICGC;COSMIC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	P00533	EGFR	P17252	PRKCA	S1162	N1169S	1169	Missense	distal	7	no	16.914	16.938	EPSD	ICGC	16.704	Up-regulation
AGC_PKC_PKCa_PRKCA_ST	P00533	EGFR	P17252	PRKCA	S1162	Q1164R	1164	Missense	proximal	2	no	16.914	20.749	EPSD	ICGC;COSMIC	16.704	Up-regulation
AGC_PKC_PKCa_PRKCA_ST	Q8WTQ7	GRK7	P17252	PRKCA	S23	D24Y	24	Missense	proximal	1	no	20.795	22.031	EPSD	ICGC	16.704	Up-regulation
AGC_PKC_PKCa_PRKCA_ST	Q8WTQ7	GRK7	P17252	PRKCA	S23	A19V	19	Missense	distal	-4	no	20.795	20.236	EPSD	ICGC;COSMIC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	Q8WTQ7	GRK7	P17252	PRKCA	S23	Y16C	16	Missense	distal	-7	no	20.795	20.781	EPSD	ICGC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	Q8WTQ7	GRK7	P17252	PRKCA	S23	R20L	20	Missense	distal	-3	no	20.795	16.440	EPSD	ICGC;COSMIC	16.704	Loss
AGC_PKC_PKCa_PRKCA_ST	Q8WTQ7	GRK7	P17252	PRKCA	S36	R33Q	33	Missense	distal	-3	no	21.178	18.321	PhosphoSitePlus	ICGC;COSMIC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	Q8WTQ7	GRK7	P17252	PRKCA	S36	A38V	38	Missense	proximal	2	no	21.178	20.863	PhosphoSitePlus	ICGC;COSMIC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	Q8WTQ7	GRK7	P17252	PRKCA	S36	Q31R	31	Missense	distal	-5	no	21.178	21.330	PhosphoSitePlus	ICGC	16.704	Up-regulation
AGC_PKC_PKCa_PRKCA_ST	Q8WTQ7	GRK7	P17252	PRKCA	S36	Q43L	43	Missense	distal	7	no	21.178	21.139	PhosphoSitePlus	ICGC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	Q8WTQ7	GRK7	P17252	PRKCA	S36	L39V	39	Missense	distal	3	no	21.178	21.562	PhosphoSitePlus	ICGC;COSMIC	16.704	Up-regulation
AGC_PKC_PKCa_PRKCA_ST	Q8WTQ7	GRK7	P17252	PRKCA	S36	G41R	41	Missense	distal	5	no	21.178	21.459	PhosphoSitePlus	ICGC;COSMIC	16.704	Up-regulation
AGC_PKC_PKCa_PRKCA_ST	Q8WTQ7	GRK7	P17252	PRKCA	S36	L39M	39	Missense	distal	3	no	21.178	22.148	PhosphoSitePlus	ICGC;COSMIC	16.704	Up-regulation
AGC_PKC_PKCa_PRKCA_ST	P02786	TFRC	P17252	PRKCA	S24	L18M	18	Missense	distal	-6	no	19.213	19.275	PhosphoSitePlus	ICGC	16.704	Up-regulation
AGC_PKC_PKCa_PRKCA_ST	P02786	TFRC	P17252	PRKCA	S132	L127R	127	Missense	distal	-5	no	21.336	21.464	EPSD	ICGC	16.704	Up-regulation
AGC_PKC_PKCa_PRKCA_ST	P02786	TFRC	P17252	PRKCA	S132	S137G	137	Missense	distal	5	no	21.336	21.197	EPSD	ICGC;COSMIC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	P02786	TFRC	P17252	PRKCA	S132	D126E	126	Missense	distal	-6	no	21.336	21.420	EPSD	ICGC	16.704	Up-regulation
AGC_PKC_PKCa_PRKCA_ST	P02786	TFRC	P17252	PRKCA	S654	T658R	658	Missense	distal	4	no	16.775	17.452	EPSD	ICGC;COSMIC	16.704	Up-regulation
AGC_PKC_PKCa_PRKCA_ST	P02786	TFRC	P17252	PRKCA	S691	P688H	688	Missense	distal	-3	no	17.785	17.777	EPSD	ICGC;COSMIC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	P10721	KIT	P17252	PRKCA	T488	E490K	490	Missense	proximal	2	no	11.614	16.893	EPSD	ICGC;COSMIC	16.704	Gain
AGC_PKC_PKCa_PRKCA_ST	P10721	KIT	P17252	PRKCA	S741	D737Y	737	Missense	distal	-4	no	22.542	23.027	PhosphoSitePlus;EPSD	ICGC;COSMIC	16.704	Up-regulation
AGC_PKC_PKCa_PRKCA_ST	P10721	KIT	P17252	PRKCA	S741	R739S	739	Missense	proximal	-2	no	22.542	19.241	PhosphoSitePlus;EPSD	ICGC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	P10721	KIT	P17252	PRKCA	S741	K735E	735	Missense	distal	-6	no	22.542	22.475	PhosphoSitePlus;EPSD	ICGC;COSMIC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	P10721	KIT	P17252	PRKCA	S746	R739S	739	Missense	distal	-7	no	17.714	17.709	EPSD;PhosphoSitePlus	ICGC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	Q9BR76	CORO1B	P17252	PRKCA	T209	R214W	214	Missense	distal	5	no	18.749	18.241	EPSD	ICGC;COSMIC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	Q9BR76	CORO1B	P17252	PRKCA	T209	R206H	206	Missense	distal	-3	no	18.749	14.893	EPSD	ICGC;COSMIC	16.704	Loss
AGC_PKC_PKCa_PRKCA_ST	Q9BR76	CORO1B	P17252	PRKCA	T209	D204N	204	Missense	distal	-5	no	18.749	18.779	EPSD	ICGC	16.704	Up-regulation
AGC_PKC_PKCa_PRKCA_ST	Q9BR76	CORO1B	P17252	PRKCA	S407	R402L	402	Missense	distal	-5	no	17.036	16.909	EPSD	ICGC;COSMIC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	Q13131	PRKAA1	P17252	PRKCA	S5	W7L	7	Missense	proximal	2	no	23.059	23.512	EPSD	ICGC;COSMIC	16.704	Up-regulation
AGC_PKC_PKCa_PRKCA_ST	Q13131	PRKAA1	P17252	PRKCA	S5	R2C	2	Missense	distal	-3	no	23.059	20.320	EPSD	ICGC;COSMIC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	Q13131	PRKAA1	P17252	PRKCA	S6	W7L	7	Missense	proximal	1	no	27.207	27.584	EPSD	ICGC;COSMIC	16.704	Up-regulation
AGC_PKC_PKCa_PRKCA_ST	Q13131	PRKAA1	P17252	PRKCA	S6	R2C	2	Missense	distal	-4	no	27.207	25.864	EPSD	ICGC;COSMIC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	Q13131	PRKAA1	P17252	PRKCA	S496	S498C	498	Missense	proximal	2	no	17.709	17.978	PhosphoSitePlus	ICGC;COSMIC	16.704	Up-regulation
AGC_PKC_PKCa_PRKCA_ST	Q13131	PRKAA1	P17252	PRKCA	S496	R501P	501	Missense	distal	5	no	17.709	17.726	PhosphoSitePlus	ICGC;COSMIC	16.704	Up-regulation
AGC_PKC_PKCa_PRKCA_ST	Q13131	PRKAA1	P17252	PRKCA	S496	C503Y	503	Missense	distal	7	no	17.709	17.880	PhosphoSitePlus	ICGC	16.704	Up-regulation
AGC_PKC_PKCa_PRKCA_ST	Q13131	PRKAA1	P17252	PRKCA	S496	Y500C	500	Missense	distal	4	no	17.709	16.951	PhosphoSitePlus	ICGC;COSMIC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	Q13131	PRKAA1	P17252	PRKCA	S502	C503Y	503	Missense	proximal	1	no	14.701	17.174	EPSD	ICGC	16.704	Gain
AGC_PKC_PKCa_PRKCA_ST	Q13131	PRKAA1	P17252	PRKCA	S541	T543K	543	Missense	proximal	2	no	14.197	18.586	EPSD	ICGC;COSMIC	16.704	Gain
AGC_PKC_PKCa_PRKCA_ST	O60928	KCNJ13	P17252	PRKCA	S14	V21G	21	Missense	distal	7	no	20.336	20.414	EPSD	ICGC	16.704	Up-regulation
AGC_PKC_PKCa_PRKCA_ST	O60928	KCNJ13	P17252	PRKCA	S14	L13I	13	Missense	proximal	-1	no	20.336	19.472	EPSD	ICGC;COSMIC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	O60928	KCNJ13	P17252	PRKCA	S14	R18W	18	Missense	distal	4	no	20.336	18.800	EPSD	ICGC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	O60928	KCNJ13	P17252	PRKCA	S287	I281M	281	Missense	distal	-6	no	19.566	19.660	EPSD	ICGC	16.704	Up-regulation
AGC_PKC_PKCa_PRKCA_ST	Q13976	PRKG1	P17252	PRKCA	S2	L4F	4	Missense	proximal	2	no	16.242	16.926	EPSD	ICGC	16.704	Gain
AGC_PKC_PKCa_PRKCA_ST	Q13976	PRKG1	P17252	PRKCA	S2	E6K	6	Missense	distal	4	no	16.242	16.781	EPSD	ICGC	16.704	Gain
AGC_PKC_PKCa_PRKCA_ST	Q13976	PRKG1	P17252	PRKCA	S27	E23K	23	Missense	distal	-4	no	23.289	24.020	EPSD	ICGC	16.704	Up-regulation
AGC_PKC_PKCa_PRKCA_ST	P01116	KRAS	P17252	PRKCA	S39	I36M	36	Missense	distal	-3	no	15.627	17.143	EPSD	ICGC;COSMIC	16.704	Gain
AGC_PKC_PKCa_PRKCA_ST	O75376	NCOR1	P17252	PRKCA	S24	Q26K	26	Missense	proximal	2	no	15.452	18.865	EPSD	ICGC;COSMIC	16.704	Gain
AGC_PKC_PKCa_PRKCA_ST	O75376	NCOR1	P17252	PRKCA	S70	P77Q	77	Missense	distal	7	no	21.046	21.052	PhosphoSitePlus	ICGC	16.704	Up-regulation
AGC_PKC_PKCa_PRKCA_ST	O75376	NCOR1	P17252	PRKCA	S70	P69L	69	Missense	proximal	-1	no	21.046	20.927	PhosphoSitePlus	ICGC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	O75376	NCOR1	P17252	PRKCA	S70	P69S	69	Missense	proximal	-1	no	21.046	21.346	PhosphoSitePlus	ICGC	16.704	Up-regulation
AGC_PKC_PKCa_PRKCA_ST	O75376	NCOR1	P17252	PRKCA	S70	P69F	69	Missense	proximal	-1	no	21.046	20.638	PhosphoSitePlus	ICGC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	O75376	NCOR1	P17252	PRKCA	S70	P77T	77	Missense	distal	7	no	21.046	21.017	PhosphoSitePlus	ICGC;COSMIC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	O75376	NCOR1	P17252	PRKCA	S79	P77Q	77	Missense	proximal	-2	no	16.173	17.456	EPSD	ICGC	16.704	Gain
AGC_PKC_PKCa_PRKCA_ST	O75376	NCOR1	P17252	PRKCA	S88	P91T	91	Missense	distal	3	no	17.988	17.682	EPSD	ICGC;COSMIC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	O75376	NCOR1	P17252	PRKCA	S106	E105K	105	Missense	proximal	-1	no	20.474	20.900	EPSD	ICGC;COSMIC	16.704	Up-regulation
AGC_PKC_PKCa_PRKCA_ST	O75376	NCOR1	P17252	PRKCA	S177	E179Q	179	Missense	proximal	2	no	15.562	17.428	EPSD	ICGC	16.704	Gain
AGC_PKC_PKCa_PRKCA_ST	O75376	NCOR1	P17252	PRKCA	S401	R398W	398	Missense	distal	-3	no	19.239	16.886	EPSD	ICGC;COSMIC;CCLE	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	O75376	NCOR1	P17252	PRKCA	S401	M406I	406	Missense	distal	5	no	19.239	18.918	EPSD	ICGC;COSMIC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	O75376	NCOR1	P17252	PRKCA	S401	Q396K	396	Missense	distal	-5	no	19.239	19.379	EPSD	ICGC	16.704	Up-regulation
AGC_PKC_PKCa_PRKCA_ST	O75376	NCOR1	P17252	PRKCA	S1160	G1163E	1163	Missense	distal	3	no	19.776	19.177	EPSD	ICGC;COSMIC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	O75376	NCOR1	P17252	PRKCA	S1234	I1241M	1241	Missense	distal	7	no	19.627	19.791	EPSD	ICGC	16.704	Up-regulation
AGC_PKC_PKCa_PRKCA_ST	O75376	NCOR1	P17252	PRKCA	S1242	I1241M	1241	Missense	proximal	-1	no	17.676	19.618	EPSD	ICGC	16.704	Up-regulation
AGC_PKC_PKCa_PRKCA_ST	O75376	NCOR1	P17252	PRKCA	S1242	R1245Q	1245	Missense	distal	3	no	17.676	15.223	EPSD	ICGC;COSMIC	16.704	Loss
AGC_PKC_PKCa_PRKCA_ST	O75376	NCOR1	P17252	PRKCA	T1524	S1528C	1528	Missense	distal	4	no	17.189	16.034	EPSD	ICGC;COSMIC	16.704	Loss
AGC_PKC_PKCa_PRKCA_ST	O75376	NCOR1	P17252	PRKCA	S1528	S1528C	1528	Missense	central	0	yes	18.458	0.000	EPSD	ICGC;COSMIC	16.704	Loss
AGC_PKC_PKCa_PRKCA_ST	O75376	NCOR1	P17252	PRKCA	S1636	Q1640K	1640	Missense	distal	4	no	21.557	21.946	EPSD	ICGC	16.704	Up-regulation
AGC_PKC_PKCa_PRKCA_ST	O75376	NCOR1	P17252	PRKCA	S1695	P1689H	1689	Missense	distal	-6	no	16.938	16.975	EPSD	ICGC	16.704	Up-regulation
AGC_PKC_PKCa_PRKCA_ST	O75376	NCOR1	P17252	PRKCA	S1695	P1690L	1690	Missense	distal	-5	no	16.938	16.911	EPSD	ICGC;COSMIC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	O75376	NCOR1	P17252	PRKCA	S1760	R1755W	1755	Missense	distal	-5	no	17.669	17.355	EPSD	ICGC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	Q9UQ13	SHOC2	P17252	PRKCA	S57	A60S	60	Missense	distal	3	no	16.544	16.751	EPSD	ICGC;COSMIC	16.704	Gain
AGC_PKC_PKCa_PRKCA_ST	Q9UQ13	SHOC2	P17252	PRKCA	S57	Q61K	61	Missense	distal	4	no	16.544	16.933	EPSD	ICGC;COSMIC	16.704	Gain
AGC_PKC_PKCa_PRKCA_ST	Q9UQ13	SHOC2	P17252	PRKCA	T71	T71M	71	Missense	central	0	yes	17.247	0.000	EPSD;PhosphoSitePlus	ICGC;COSMIC	16.704	Loss
AGC_PKC_PKCa_PRKCA_ST	Q9UQ13	SHOC2	P17252	PRKCA	T71	A78S	78	Missense	distal	7	no	17.247	17.249	EPSD;PhosphoSitePlus	ICGC	16.704	Up-regulation
AGC_PKC_PKCa_PRKCA_ST	Q9UQ13	SHOC2	P17252	PRKCA	T81	A78S	78	Missense	distal	-3	no	16.299	17.878	EPSD	ICGC	16.704	Gain
AGC_PKC_PKCa_PRKCA_ST	Q9UQ13	SHOC2	P17252	PRKCA	S85	A78S	78	Missense	distal	-7	no	17.159	17.157	EPSD	ICGC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	Q9UQ13	SHOC2	P17252	PRKCA	S85	K84Q	84	Missense	proximal	-1	no	17.159	16.284	EPSD	ICGC;COSMIC	16.704	Loss
AGC_PKC_PKCa_PRKCA_ST	Q9UQ13	SHOC2	P17252	PRKCA	S221	L217V	217	Missense	distal	-4	no	22.884	22.843	EPSD	ICGC;COSMIC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	Q9UQ13	SHOC2	P17252	PRKCA	S221	L214F	214	Missense	distal	-7	no	22.884	22.882	EPSD	ICGC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	P29350	PTPN6	P17252	PRKCA	S42	S42L	42	Missense	central	0	yes	17.466	0.000	EPSD	ICGC;COSMIC	16.704	Loss
AGC_PKC_PKCa_PRKCA_ST	P29350	PTPN6	P17252	PRKCA	S582	K589N	589	Missense	distal	7	no	16.827	16.707	EPSD	ICGC;COSMIC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	P29350	PTPN6	P17252	PRKCA	S591	K589N	589	Missense	proximal	-2	no	19.441	17.872	PhosphoSitePlus	ICGC;COSMIC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	P42261	GRIA1	P17252	PRKCA	S79	G81R	81	Missense	proximal	2	no	13.375	18.621	EPSD	ICGC;COSMIC	16.704	Gain
AGC_PKC_PKCa_PRKCA_ST	P42261	GRIA1	P17252	PRKCA	S306	Q310H	310	Missense	distal	4	no	19.207	19.142	EPSD	ICGC;COSMIC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	P42261	GRIA1	P17252	PRKCA	S306	R311K	311	Missense	distal	5	no	19.207	19.351	EPSD	ICGC;COSMIC	16.704	Up-regulation
AGC_PKC_PKCa_PRKCA_ST	P42261	GRIA1	P17252	PRKCA	S306	R308W	308	Missense	proximal	2	no	19.207	13.767	EPSD	ICGC;COSMIC	16.704	Loss
AGC_PKC_PKCa_PRKCA_ST	P42261	GRIA1	P17252	PRKCA	S306	A303P	303	Missense	distal	-3	no	19.207	19.807	EPSD	ICGC;COSMIC	16.704	Up-regulation
AGC_PKC_PKCa_PRKCA_ST	P42261	GRIA1	P17252	PRKCA	S306	S306I	306	Missense	central	0	yes	19.207	0.000	EPSD	ICGC	16.704	Loss
AGC_PKC_PKCa_PRKCA_ST	P42261	GRIA1	P17252	PRKCA	S306	S306N	306	Missense	central	0	yes	19.207	0.000	EPSD	ICGC	16.704	Loss
AGC_PKC_PKCa_PRKCA_ST	P42261	GRIA1	P17252	PRKCA	S306	R308Q	308	Missense	proximal	2	no	19.207	15.373	EPSD	ICGC;COSMIC;GDSC;CCLE	16.704	Loss
AGC_PKC_PKCa_PRKCA_ST	P42261	GRIA1	P17252	PRKCA	S306	D313N	313	Missense	distal	7	no	19.207	19.181	EPSD	ICGC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	P42261	GRIA1	P17252	PRKCA	S306	Q305H	305	Missense	proximal	-1	no	19.207	19.702	EPSD	ICGC	16.704	Up-regulation
AGC_PKC_PKCa_PRKCA_ST	P42261	GRIA1	P17252	PRKCA	S306	S306C	306	Missense	central	0	yes	19.207	0.000	EPSD	ICGC	16.704	Loss
AGC_PKC_PKCa_PRKCA_ST	P42261	GRIA1	P17252	PRKCA	S306	A301T	301	Missense	distal	-5	no	19.207	19.588	EPSD	ICGC;COSMIC	16.704	Up-regulation
AGC_PKC_PKCa_PRKCA_ST	P42261	GRIA1	P17252	PRKCA	S453	R455H	455	Missense	proximal	2	no	16.799	11.775	EPSD	ICGC;COSMIC;GDSC;CCLE	16.704	Loss
AGC_PKC_PKCa_PRKCA_ST	P42261	GRIA1	P17252	PRKCA	S453	V450M	450	Missense	distal	-3	no	16.799	17.517	EPSD	ICGC;COSMIC	16.704	Up-regulation
AGC_PKC_PKCa_PRKCA_ST	P42261	GRIA1	P17252	PRKCA	S453	A447P	447	Missense	distal	-6	no	16.799	16.804	EPSD	ICGC;COSMIC	16.704	Up-regulation
AGC_PKC_PKCa_PRKCA_ST	P42261	GRIA1	P17252	PRKCA	S453	H449Q	449	Missense	distal	-4	no	16.799	16.996	EPSD	ICGC;COSMIC	16.704	Up-regulation
AGC_PKC_PKCa_PRKCA_ST	P42261	GRIA1	P17252	PRKCA	S453	V450L	450	Missense	distal	-3	no	16.799	16.133	EPSD	ICGC	16.704	Loss
AGC_PKC_PKCa_PRKCA_ST	P42261	GRIA1	P17252	PRKCA	S453	Y452C	452	Missense	proximal	-1	no	16.799	14.976	EPSD	ICGC;COSMIC	16.704	Loss
AGC_PKC_PKCa_PRKCA_ST	P42261	GRIA1	P17252	PRKCA	S453	Y454C	454	Missense	proximal	1	no	16.799	14.326	EPSD	ICGC	16.704	Loss
AGC_PKC_PKCa_PRKCA_ST	P42261	GRIA1	P17252	PRKCA	S645	E651D	651	Missense	distal	6	no	17.389	17.406	EPSD	ICGC	16.704	Up-regulation
AGC_PKC_PKCa_PRKCA_ST	P42261	GRIA1	P17252	PRKCA	S645	V640M	640	Missense	distal	-5	no	17.389	17.787	EPSD	ICGC;COSMIC	16.704	Up-regulation
AGC_PKC_PKCa_PRKCA_ST	P42261	GRIA1	P17252	PRKCA	S645	E648Q	648	Missense	distal	3	no	17.389	16.175	EPSD	ICGC;COSMIC	16.704	Loss
AGC_PKC_PKCa_PRKCA_ST	P42261	GRIA1	P17252	PRKCA	S645	E648D	648	Missense	distal	3	no	17.389	16.903	EPSD	ICGC;COSMIC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	P42261	GRIA1	P17252	PRKCA	S645	P646L	646	Missense	proximal	1	no	17.389	17.816	EPSD	ICGC;COSMIC	16.704	Up-regulation
AGC_PKC_PKCa_PRKCA_ST	P42261	GRIA1	P17252	PRKCA	S645	D652N	652	Missense	distal	7	no	17.389	17.363	EPSD	ICGC;COSMIC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	P42261	GRIA1	P17252	PRKCA	S645	R642K	642	Missense	distal	-3	no	17.389	15.363	EPSD	ICGC;COSMIC	16.704	Loss
AGC_PKC_PKCa_PRKCA_ST	P42261	GRIA1	P17252	PRKCA	S832	M839I	839	Missense	distal	7	no	16.903	16.739	EPSD	ICGC;COSMIC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	P42261	GRIA1	P17252	PRKCA	S832	L825S	825	Missense	distal	-7	no	16.903	16.909	EPSD	ICGC;COSMIC	16.704	Up-regulation
AGC_PKC_PKCa_PRKCA_ST	P42261	GRIA1	P17252	PRKCA	S832	R833C	833	Missense	proximal	1	no	16.903	14.068	EPSD	ICGC	16.704	Loss
AGC_PKC_PKCa_PRKCA_ST	P42261	GRIA1	P17252	PRKCA	S832	E827A	827	Missense	distal	-5	no	16.903	16.731	EPSD	ICGC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	P42261	GRIA1	P17252	PRKCA	S832	R833L	833	Missense	proximal	1	no	16.903	16.556	EPSD	ICGC;COSMIC	16.704	Loss
AGC_PKC_PKCa_PRKCA_ST	P42261	GRIA1	P17252	PRKCA	S832	C829F	829	Missense	distal	-3	no	16.903	17.022	EPSD	ICGC;COSMIC	16.704	Up-regulation
AGC_PKC_PKCa_PRKCA_ST	P42261	GRIA1	P17252	PRKCA	S832	Y830C	830	Missense	proximal	-2	no	16.903	17.932	EPSD	ICGC;COSMIC	16.704	Up-regulation
AGC_PKC_PKCa_PRKCA_ST	P42261	GRIA1	P17252	PRKCA	S832	S832F	832	Missense	central	0	yes	16.903	0.000	EPSD	ICGC;COSMIC	16.704	Loss
AGC_PKC_PKCa_PRKCA_ST	P42261	GRIA1	P17252	PRKCA	S832	R833H	833	Missense	proximal	1	no	16.903	16.090	EPSD	ICGC;COSMIC	16.704	Loss
AGC_PKC_PKCa_PRKCA_ST	P42261	GRIA1	P17252	PRKCA	S832	F828L	828	Missense	distal	-4	no	16.903	16.531	EPSD	ICGC;COSMIC	16.704	Loss
AGC_PKC_PKCa_PRKCA_ST	P42261	GRIA1	P17252	PRKCA	S832	R838W	838	Missense	distal	6	no	16.903	16.656	EPSD	ICGC;GDSC	16.704	Loss
AGC_PKC_PKCa_PRKCA_ST	P42261	GRIA1	P17252	PRKCA	S832	R838Q	838	Missense	distal	6	no	16.903	16.781	EPSD	ICGC;COSMIC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	P42261	GRIA1	P17252	PRKCA	S836	M839I	839	Missense	distal	3	no	25.598	24.316	PhosphoSitePlus;EPSD	ICGC;COSMIC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	P42261	GRIA1	P17252	PRKCA	S836	R833C	833	Missense	distal	-3	no	25.598	22.858	PhosphoSitePlus;EPSD	ICGC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	P42261	GRIA1	P17252	PRKCA	S836	R833L	833	Missense	distal	-3	no	25.598	21.242	PhosphoSitePlus;EPSD	ICGC;COSMIC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	P42261	GRIA1	P17252	PRKCA	S836	C829F	829	Missense	distal	-7	no	25.598	25.604	PhosphoSitePlus;EPSD	ICGC;COSMIC	16.704	Up-regulation
AGC_PKC_PKCa_PRKCA_ST	P42261	GRIA1	P17252	PRKCA	S836	Y830C	830	Missense	distal	-6	no	25.598	25.355	PhosphoSitePlus;EPSD	ICGC;COSMIC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	P42261	GRIA1	P17252	PRKCA	S836	S832F	832	Missense	distal	-4	no	25.598	25.539	PhosphoSitePlus;EPSD	ICGC;COSMIC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	P42261	GRIA1	P17252	PRKCA	S836	R833H	833	Missense	distal	-3	no	25.598	21.741	PhosphoSitePlus;EPSD	ICGC;COSMIC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	P42261	GRIA1	P17252	PRKCA	S836	G841D	841	Missense	distal	5	no	25.598	25.517	PhosphoSitePlus;EPSD	ICGC;COSMIC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	P42261	GRIA1	P17252	PRKCA	S836	R838W	838	Missense	proximal	2	no	25.598	20.158	PhosphoSitePlus;EPSD	ICGC;GDSC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	P42261	GRIA1	P17252	PRKCA	S836	R838Q	838	Missense	proximal	2	no	25.598	21.763	PhosphoSitePlus;EPSD	ICGC;COSMIC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	P42261	GRIA1	P17252	PRKCA	S849	E852K	852	Missense	distal	3	no	16.504	17.120	EPSD;PhosphoSitePlus	ICGC;COSMIC	16.704	Gain
AGC_PKC_PKCa_PRKCA_ST	P42261	GRIA1	P17252	PRKCA	S849	Q848K	848	Missense	proximal	-1	no	16.504	17.378	EPSD;PhosphoSitePlus	ICGC;COSMIC	16.704	Gain
AGC_PKC_PKCa_PRKCA_ST	P42261	GRIA1	P17252	PRKCA	T858	P860H	860	Missense	proximal	2	no	17.098	17.277	EPSD	ICGC;COSMIC	16.704	Up-regulation
AGC_PKC_PKCa_PRKCA_ST	P42261	GRIA1	P17252	PRKCA	T858	E852K	852	Missense	distal	-6	no	17.098	17.165	EPSD	ICGC;COSMIC	16.704	Up-regulation
AGC_PKC_PKCa_PRKCA_ST	P42261	GRIA1	P17252	PRKCA	T858	R855W	855	Missense	distal	-3	no	17.098	14.744	EPSD	ICGC;COSMIC	16.704	Loss
AGC_PKC_PKCa_PRKCA_ST	P42261	GRIA1	P17252	PRKCA	T858	R861H	861	Missense	distal	3	no	17.098	16.386	EPSD	ICGC;COSMIC	16.704	Loss
AGC_PKC_PKCa_PRKCA_ST	P42261	GRIA1	P17252	PRKCA	T858	P860T	860	Missense	proximal	2	no	17.098	17.490	EPSD	ICGC;COSMIC	16.704	Up-regulation
AGC_PKC_PKCa_PRKCA_ST	P42261	GRIA1	P17252	PRKCA	T858	R861C	861	Missense	distal	3	no	17.098	14.480	EPSD	ICGC;COSMIC	16.704	Loss
AGC_PKC_PKCa_PRKCA_ST	P42261	GRIA1	P17252	PRKCA	T858	N862K	862	Missense	distal	4	no	17.098	18.225	EPSD	ICGC;COSMIC	16.704	Up-regulation
AGC_PKC_PKCa_PRKCA_ST	P42261	GRIA1	P17252	PRKCA	T858	S857L	857	Missense	proximal	-1	no	17.098	16.678	EPSD	ICGC;COSMIC;GDSC;CCLE	16.704	Loss
AGC_PKC_PKCa_PRKCA_ST	P42261	GRIA1	P17252	PRKCA	T858	P860S	860	Missense	proximal	2	no	17.098	17.681	EPSD	ICGC;COSMIC	16.704	Up-regulation
AGC_PKC_PKCa_PRKCA_ST	P35869	AHR	P17252	PRKCA	S12	K14N	14	Missense	proximal	2	no	21.715	16.766	PhosphoSitePlus;EPSD	ICGC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	P35869	AHR	P17252	PRKCA	S12	P18L	18	Missense	distal	6	no	21.715	21.671	PhosphoSitePlus;EPSD	ICGC;COSMIC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	P35869	AHR	P17252	PRKCA	S36	N34T	34	Missense	proximal	-2	no	21.241	21.544	EPSD;PhosphoSitePlus	ICGC;COSMIC	16.704	Up-regulation
AGC_PKC_PKCa_PRKCA_ST	P35869	AHR	P17252	PRKCA	S36	K37T	37	Missense	proximal	1	no	21.241	20.357	EPSD;PhosphoSitePlus	ICGC;COSMIC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	P35869	AHR	P17252	PRKCA	S36	R38L	38	Missense	proximal	2	no	21.241	16.254	EPSD;PhosphoSitePlus	ICGC;COSMIC	16.704	Loss
AGC_PKC_PKCa_PRKCA_ST	P35611	ADD1	P17252	PRKCA	S59	A66S	66	Missense	distal	7	no	16.841	16.843	EPSD	ICGC	16.704	Up-regulation
AGC_PKC_PKCa_PRKCA_ST	P35611	ADD1	P17252	PRKCA	S59	M52I	52	Missense	distal	-7	no	16.841	16.829	EPSD	ICGC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	P35611	ADD1	P17252	PRKCA	S59	V58A	58	Missense	proximal	-1	no	16.841	17.745	EPSD	ICGC;COSMIC	16.704	Up-regulation
AGC_PKC_PKCa_PRKCA_ST	P35611	ADD1	P17252	PRKCA	S59	M60K	60	Missense	proximal	1	no	16.841	17.440	EPSD	ICGC;COSMIC	16.704	Up-regulation
AGC_PKC_PKCa_PRKCA_ST	P35611	ADD1	P17252	PRKCA	S353	P359L	359	Missense	distal	6	no	16.821	16.777	EPSD	ICGC;COSMIC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	P35611	ADD1	P17252	PRKCA	S353	G357V	357	Missense	distal	4	no	16.821	15.857	EPSD	ICGC	16.704	Loss
AGC_PKC_PKCa_PRKCA_ST	P35611	ADD1	P17252	PRKCA	S353	P359T	359	Missense	distal	6	no	16.821	16.739	EPSD	ICGC;COSMIC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	P35611	ADD1	P17252	PRKCA	S358	P359L	359	Missense	proximal	1	no	17.039	17.466	EPSD	ICGC;COSMIC	16.704	Up-regulation
AGC_PKC_PKCa_PRKCA_ST	P35611	ADD1	P17252	PRKCA	S358	G357V	357	Missense	proximal	-1	no	17.039	15.329	EPSD	ICGC	16.704	Loss
AGC_PKC_PKCa_PRKCA_ST	P35611	ADD1	P17252	PRKCA	S358	G365V	365	Missense	distal	7	no	17.039	16.961	EPSD	ICGC;COSMIC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	P35611	ADD1	P17252	PRKCA	S358	P359T	359	Missense	proximal	1	no	17.039	16.967	EPSD	ICGC;COSMIC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	P35611	ADD1	P17252	PRKCA	S404	K403T	403	Missense	proximal	-1	no	20.626	19.804	EPSD	ICGC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	P35611	ADD1	P17252	PRKCA	S404	S408I	408	Missense	distal	4	no	20.626	19.182	EPSD	ICGC;COSMIC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	P35611	ADD1	P17252	PRKCA	S436	P432T	432	Missense	distal	-4	no	18.846	18.356	EPSD	ICGC;COSMIC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	P35611	ADD1	P17252	PRKCA	S450	R452W	452	Missense	proximal	2	no	20.964	15.524	EPSD	ICGC	16.704	Loss
AGC_PKC_PKCa_PRKCA_ST	P35611	ADD1	P17252	PRKCA	S450	G451C	451	Missense	proximal	1	no	20.964	19.081	EPSD	ICGC;COSMIC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	P35611	ADD1	P17252	PRKCA	S450	N449S	449	Missense	proximal	-1	no	20.964	21.121	EPSD	ICGC	16.704	Up-regulation
AGC_PKC_PKCa_PRKCA_ST	P35611	ADD1	P17252	PRKCA	S669	P667H	667	Missense	proximal	-2	no	17.233	15.722	EPSD	ICGC;COSMIC	16.704	Loss
AGC_PKC_PKCa_PRKCA_ST	P35611	ADD1	P17252	PRKCA	S716	R723C	723	Missense	distal	7	no	19.667	19.444	EPSD;PhosphoSitePlus	ICGC;COSMIC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	P35611	ADD1	P17252	PRKCA	S716	S714F	714	Missense	proximal	-2	no	19.667	18.996	EPSD;PhosphoSitePlus	ICGC;COSMIC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	P35611	ADD1	P17252	PRKCA	S716	P711S	711	Missense	distal	-5	no	19.667	19.342	EPSD;PhosphoSitePlus	ICGC;COSMIC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	P35611	ADD1	P17252	PRKCA	S716	P715L	715	Missense	proximal	-1	no	19.667	19.547	EPSD;PhosphoSitePlus	ICGC;COSMIC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	P35611	ADD1	P17252	PRKCA	S726	R723C	723	Missense	distal	-3	no	18.633	15.894	PhosphoSitePlus;EPSD	ICGC;COSMIC	16.704	Loss
AGC_PKC_PKCa_PRKCA_ST	P35611	ADD1	P17252	PRKCA	S726	P725L	725	Missense	proximal	-1	no	18.633	18.513	PhosphoSitePlus;EPSD	ICGC;COSMIC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	P35611	ADD1	P17252	PRKCA	S731	P725L	725	Missense	distal	-6	no	18.603	18.570	EPSD	ICGC;COSMIC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	P49802	RGS7	P17252	PRKCA	S241	S239R	239	Missense	proximal	-2	no	15.544	18.846	EPSD	ICGC;COSMIC	16.704	Gain
AGC_PKC_PKCa_PRKCA_ST	P49802	RGS7	P17252	PRKCA	S323	K328T	328	Missense	distal	5	no	17.009	16.548	EPSD	ICGC	16.704	Loss
AGC_PKC_PKCa_PRKCA_ST	P49802	RGS7	P17252	PRKCA	S323	S319R	319	Missense	distal	-4	no	17.009	17.202	EPSD	ICGC	16.704	Up-regulation
AGC_PKC_PKCa_PRKCA_ST	P49802	RGS7	P17252	PRKCA	S463	R460H	460	Missense	distal	-3	no	20.138	16.281	EPSD	ICGC;COSMIC	16.704	Loss
AGC_PKC_PKCa_PRKCA_ST	P49802	RGS7	P17252	PRKCA	S463	M458T	458	Missense	distal	-5	no	20.138	20.205	EPSD	ICGC;COSMIC	16.704	Up-regulation
AGC_PKC_PKCa_PRKCA_ST	P49802	RGS7	P17252	PRKCA	S463	Q469K	469	Missense	distal	6	no	20.138	20.248	EPSD	ICGC	16.704	Up-regulation
AGC_PKC_PKCa_PRKCA_ST	P49802	RGS7	P17252	PRKCA	S463	M458I	458	Missense	distal	-5	no	20.138	19.733	EPSD	ICGC;COSMIC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	P49802	RGS7	P17252	PRKCA	S463	Q469H	469	Missense	distal	6	no	20.138	20.183	EPSD	ICGC;COSMIC	16.704	Up-regulation
AGC_PKC_PKCa_PRKCA_ST	P49802	RGS7	P17252	PRKCA	S463	N470Y	470	Missense	distal	7	no	20.138	20.155	EPSD	ICGC	16.704	Up-regulation
AGC_PKC_PKCa_PRKCA_ST	P49802	RGS7	P17252	PRKCA	S463	R461K	461	Missense	proximal	-2	no	20.138	18.510	EPSD	ICGC;COSMIC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	Q92681	RSC1A1	P17252	PRKCA	S66	F62L	62	Missense	distal	-4	no	17.835	17.462	EPSD	ICGC;COSMIC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	Q92681	RSC1A1	P17252	PRKCA	S66	L72V	72	Missense	distal	6	no	17.835	17.757	EPSD	ICGC;COSMIC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	Q92681	RSC1A1	P17252	PRKCA	S477	V473F	473	Missense	distal	-4	no	16.303	16.717	EPSD	ICGC	16.704	Gain
AGC_PKC_PKCa_PRKCA_ST	P81274	GPSM2	P17252	PRKCA	S7	M8T	8	Missense	proximal	1	no	19.604	19.319	EPSD	ICGC;COSMIC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	P81274	GPSM2	P17252	PRKCA	S408	R406W	406	Missense	proximal	-2	no	21.986	19.988	PhosphoSitePlus	ICGC;COSMIC;GDSC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	P81274	GPSM2	P17252	PRKCA	S460	A467S	467	Missense	distal	7	no	16.759	16.761	EPSD	ICGC;COSMIC	16.704	Up-regulation
AGC_PKC_PKCa_PRKCA_ST	P81274	GPSM2	P17252	PRKCA	S478	D472Y	472	Missense	distal	-6	no	17.087	17.118	EPSD	ICGC;COSMIC	16.704	Up-regulation
AGC_PKC_PKCa_PRKCA_ST	P81274	GPSM2	P17252	PRKCA	S478	R474Q	474	Missense	distal	-4	no	17.087	16.709	EPSD	ICGC;COSMIC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	P81274	GPSM2	P17252	PRKCA	S478	N477H	477	Missense	proximal	-1	no	17.087	17.308	EPSD	ICGC;COSMIC	16.704	Up-regulation
AGC_PKC_PKCa_PRKCA_ST	P81274	GPSM2	P17252	PRKCA	S556	R557C	557	Missense	proximal	1	no	18.532	15.696	EPSD	ICGC	16.704	Loss
AGC_PKC_PKCa_PRKCA_ST	P81274	GPSM2	P17252	PRKCA	S556	R557H	557	Missense	proximal	1	no	18.532	17.719	EPSD	ICGC;COSMIC;GDSC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	P81274	GPSM2	P17252	PRKCA	S565	S567T	567	Missense	proximal	2	no	18.244	18.053	EPSD	ICGC;COSMIC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	P81274	GPSM2	P17252	PRKCA	S677	L671F	671	Missense	distal	-6	no	18.308	18.288	EPSD	ICGC;COSMIC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	P81274	GPSM2	P17252	PRKCA	S677	E673D	673	Missense	distal	-4	no	18.308	18.132	EPSD	ICGC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	P81274	GPSM2	P17252	PRKCA	S677	S681L	681	Missense	distal	4	no	18.308	17.516	EPSD	ICGC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	P11309	PIM1	P17252	PRKCA	S65	H68Y	68	Missense	distal	3	no	22.985	21.429	PhosphoSitePlus	ICGC;COSMIC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	P35503	UGT1A3	P17252	PRKCA	S28	L32F	32	Missense	distal	4	no	19.483	19.914	EPSD	ICGC;COSMIC	16.704	Up-regulation
AGC_PKC_PKCa_PRKCA_ST	P35503	UGT1A3	P17252	PRKCA	S43	V47A	47	Missense	distal	4	no	18.448	19.786	PhosphoSitePlus	ICGC;COSMIC	16.704	Up-regulation
AGC_PKC_PKCa_PRKCA_ST	P35503	UGT1A3	P17252	PRKCA	S43	R45W	45	Missense	proximal	2	no	18.448	13.008	PhosphoSitePlus	ICGC;COSMIC	16.704	Loss
AGC_PKC_PKCa_PRKCA_ST	P35503	UGT1A3	P17252	PRKCA	S43	W41L	41	Missense	proximal	-2	no	18.448	17.757	PhosphoSitePlus	ICGC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	P35503	UGT1A3	P17252	PRKCA	S436	M442I	442	Missense	distal	6	no	17.577	17.544	EPSD	ICGC;COSMIC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	P35503	UGT1A3	P17252	PRKCA	S436	R443H	443	Missense	distal	7	no	17.577	17.506	EPSD	ICGC;COSMIC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	P35503	UGT1A3	P17252	PRKCA	S436	N433S	433	Missense	distal	-3	no	17.577	18.934	EPSD	ICGC;COSMIC	16.704	Up-regulation
AGC_PKC_PKCa_PRKCA_ST	P35503	UGT1A3	P17252	PRKCA	S436	I441S	441	Missense	distal	5	no	17.577	17.771	EPSD	ICGC	16.704	Up-regulation
AGC_PKC_PKCa_PRKCA_ST	P35503	UGT1A3	P17252	PRKCA	S436	N440K	440	Missense	distal	4	no	17.577	18.704	EPSD	ICGC;COSMIC	16.704	Up-regulation
AGC_PKC_PKCa_PRKCA_ST	Q13224	GRIN2B	P17252	PRKCA	S383	K382N	382	Missense	proximal	-1	no	17.582	16.981	EPSD	ICGC;COSMIC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	Q13224	GRIN2B	P17252	PRKCA	S1043	R1048C	1048	Missense	distal	5	no	19.592	18.860	EPSD	ICGC;COSMIC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	Q13224	GRIN2B	P17252	PRKCA	S1043	S1046R	1046	Missense	distal	3	no	19.592	20.983	EPSD	ICGC	16.704	Up-regulation
AGC_PKC_PKCa_PRKCA_ST	Q13224	GRIN2B	P17252	PRKCA	S1043	Y1039N	1039	Missense	distal	-4	no	19.592	19.456	EPSD	ICGC;COSMIC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	Q13224	GRIN2B	P17252	PRKCA	S1303	D1305N	1305	Missense	proximal	2	no	18.841	18.750	EPSD	ICGC;COSMIC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	Q13224	GRIN2B	P17252	PRKCA	S1303	R1300W	1300	Missense	distal	-3	no	18.841	16.487	EPSD	ICGC;COSMIC	16.704	Loss
AGC_PKC_PKCa_PRKCA_ST	Q13224	GRIN2B	P17252	PRKCA	S1303	S1303P	1303	Missense	central	0	yes	18.841	0.000	EPSD	ICGC	16.704	Loss
AGC_PKC_PKCa_PRKCA_ST	Q13224	GRIN2B	P17252	PRKCA	S1323	A1316T	1316	Missense	distal	-7	no	21.123	21.119	PhosphoSitePlus	ICGC;COSMIC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	Q13224	GRIN2B	P17252	PRKCA	S1323	R1320S	1320	Missense	distal	-3	no	21.123	18.254	PhosphoSitePlus	ICGC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	Q13224	GRIN2B	P17252	PRKCA	S1323	G1328S	1328	Missense	distal	5	no	21.123	21.263	PhosphoSitePlus	ICGC	16.704	Up-regulation
AGC_PKC_PKCa_PRKCA_ST	Q13224	GRIN2B	P17252	PRKCA	S1323	R1329Q	1329	Missense	distal	6	no	21.123	21.001	PhosphoSitePlus	ICGC;COSMIC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	Q13224	GRIN2B	P17252	PRKCA	T1410	T1410M	1410	Missense	central	0	yes	18.718	0.000	EPSD	ICGC	16.704	Loss
AGC_PKC_PKCa_PRKCA_ST	Q96MS0	ROBO3	P17252	PRKCA	S402	G399W	399	Missense	distal	-3	no	16.282	17.189	EPSD	ICGC	16.704	Gain
AGC_PKC_PKCa_PRKCA_ST	Q96MS0	ROBO3	P17252	PRKCA	S404	G399W	399	Missense	distal	-5	no	19.215	19.191	EPSD	ICGC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	Q96MS0	ROBO3	P17252	PRKCA	S404	S404Y	404	Missense	central	0	yes	19.215	0.000	EPSD	ICGC;COSMIC	16.704	Loss
AGC_PKC_PKCa_PRKCA_ST	Q96MS0	ROBO3	P17252	PRKCA	S404	V403M	403	Missense	proximal	-1	no	19.215	21.337	EPSD	ICGC;COSMIC	16.704	Up-regulation
AGC_PKC_PKCa_PRKCA_ST	Q96MS0	ROBO3	P17252	PRKCA	S725	Q722K	722	Missense	distal	-3	no	17.882	18.713	EPSD	ICGC;COSMIC	16.704	Up-regulation
AGC_PKC_PKCa_PRKCA_ST	Q96MS0	ROBO3	P17252	PRKCA	S725	Q722R	722	Missense	distal	-3	no	17.882	20.739	EPSD	ICGC;COSMIC	16.704	Up-regulation
AGC_PKC_PKCa_PRKCA_ST	Q96MS0	ROBO3	P17252	PRKCA	S725	T729S	729	Missense	distal	4	no	17.882	18.312	EPSD	ICGC;COSMIC	16.704	Up-regulation
AGC_PKC_PKCa_PRKCA_ST	Q96MS0	ROBO3	P17252	PRKCA	T729	Q722K	722	Missense	distal	-7	no	16.765	16.768	EPSD	ICGC;COSMIC	16.704	Up-regulation
AGC_PKC_PKCa_PRKCA_ST	Q96MS0	ROBO3	P17252	PRKCA	T729	Q722R	722	Missense	distal	-7	no	16.765	16.773	EPSD	ICGC;COSMIC	16.704	Up-regulation
AGC_PKC_PKCa_PRKCA_ST	Q96MS0	ROBO3	P17252	PRKCA	S1293	G1289D	1289	Missense	distal	-4	no	16.763	15.994	EPSD	ICGC;COSMIC	16.704	Loss
AGC_PKC_PKCa_PRKCA_ST	Q96MS0	ROBO3	P17252	PRKCA	S1293	R1296W	1296	Missense	distal	3	no	16.763	13.830	EPSD	ICGC;COSMIC	16.704	Loss
AGC_PKC_PKCa_PRKCA_ST	Q96MS0	ROBO3	P17252	PRKCA	S1293	S1290I	1290	Missense	distal	-3	no	16.763	15.146	EPSD	ICGC	16.704	Loss
AGC_PKC_PKCa_PRKCA_ST	Q96MS0	ROBO3	P17252	PRKCA	S1293	A1288E	1288	Missense	distal	-5	no	16.763	16.936	EPSD	ICGC;COSMIC	16.704	Up-regulation
AGC_PKC_PKCa_PRKCA_ST	Q96MS0	ROBO3	P17252	PRKCA	S1352	R1359Q	1359	Missense	distal	7	no	17.444	17.440	EPSD	ICGC;COSMIC;CCLE	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	Q96MS0	ROBO3	P17252	PRKCA	S1352	S1348F	1348	Missense	distal	-4	no	17.444	17.386	EPSD	ICGC;COSMIC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	Q96MS0	ROBO3	P17252	PRKCA	S1352	S1349F	1349	Missense	distal	-3	no	17.444	17.694	EPSD	ICGC	16.704	Up-regulation
AGC_PKC_PKCa_PRKCA_ST	Q96MS0	ROBO3	P17252	PRKCA	S1353	R1359Q	1359	Missense	distal	6	no	19.296	19.174	EPSD	ICGC;COSMIC;CCLE	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	Q96MS0	ROBO3	P17252	PRKCA	S1353	S1348F	1348	Missense	distal	-5	no	19.296	19.399	EPSD	ICGC;COSMIC	16.704	Up-regulation
AGC_PKC_PKCa_PRKCA_ST	Q96MS0	ROBO3	P17252	PRKCA	S1353	S1349F	1349	Missense	distal	-4	no	19.296	19.238	EPSD	ICGC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	Q96MS0	ROBO3	P17252	PRKCA	S1358	R1359Q	1359	Missense	proximal	1	no	17.869	17.752	EPSD	ICGC;COSMIC;CCLE	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	Q96MS0	ROBO3	P17252	PRKCA	S1358	S1364G	1364	Missense	distal	6	no	17.869	17.791	EPSD	ICGC;COSMIC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	Q96MS0	ROBO3	P17252	PRKCA	S1374	R1367Q	1367	Missense	distal	-7	no	20.755	20.746	EPSD	ICGC;COSMIC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	Q96MS0	ROBO3	P17252	PRKCA	S1374	R1367W	1367	Missense	distal	-7	no	20.755	20.738	EPSD	ICGC;COSMIC;CCLE	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	P06127	CD5	P17252	PRKCA	S42	L48P	48	Missense	distal	6	no	17.565	17.609	EPSD	ICGC;COSMIC	16.704	Up-regulation
AGC_PKC_PKCa_PRKCA_ST	P06127	CD5	P17252	PRKCA	S42	R39H	39	Missense	distal	-3	no	17.565	13.709	EPSD	ICGC;COSMIC	16.704	Loss
AGC_PKC_PKCa_PRKCA_ST	P06127	CD5	P17252	PRKCA	S42	R39L	39	Missense	distal	-3	no	17.565	13.209	EPSD	ICGC	16.704	Loss
AGC_PKC_PKCa_PRKCA_ST	P06127	CD5	P17252	PRKCA	S42	R39S	39	Missense	distal	-3	no	17.565	14.695	EPSD	ICGC;COSMIC	16.704	Loss
AGC_PKC_PKCa_PRKCA_ST	P06127	CD5	P17252	PRKCA	T142	P146T	146	Missense	distal	4	no	17.394	17.163	EPSD	ICGC;COSMIC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	P06127	CD5	P17252	PRKCA	S309	R307M	307	Missense	proximal	-2	no	19.187	17.206	EPSD	ICGC;COSMIC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	P06127	CD5	P17252	PRKCA	S309	A306D	306	Missense	distal	-3	no	19.187	18.594	EPSD	ICGC;COSMIC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	P06127	CD5	P17252	PRKCA	T436	A435S	435	Missense	proximal	-1	no	16.941	17.501	EPSD;PhosphoSitePlus	ICGC	16.704	Up-regulation
AGC_PKC_PKCa_PRKCA_ST	P06127	CD5	P17252	PRKCA	T436	V437F	437	Missense	proximal	1	no	16.941	17.474	EPSD;PhosphoSitePlus	ICGC	16.704	Up-regulation
AGC_PKC_PKCa_PRKCA_ST	P06127	CD5	P17252	PRKCA	S460	H461R	461	Missense	proximal	1	no	16.135	16.948	EPSD	ICGC	16.704	Gain
AGC_PKC_PKCa_PRKCA_ST	P06127	CD5	P17252	PRKCA	S463	H461R	461	Missense	proximal	-2	no	14.878	19.432	EPSD	ICGC	16.704	Gain
AGC_PKC_PKCa_PRKCA_ST	P06239	LCK	P17252	PRKCA	S42	G41C	41	Missense	proximal	-1	no	18.146	15.626	PhosphoSitePlus	ICGC	16.704	Loss
AGC_PKC_PKCa_PRKCA_ST	P06239	LCK	P17252	PRKCA	S274	S281N	281	Missense	distal	7	no	17.165	17.141	EPSD	ICGC;COSMIC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	P06239	LCK	P17252	PRKCA	S274	S281I	281	Missense	distal	7	no	17.165	17.012	EPSD	ICGC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	P32004	L1CAM	P17252	PRKCA	S1146	L1140I	1140	Missense	distal	-6	no	17.681	17.649	EPSD	ICGC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	P32004	L1CAM	P17252	PRKCA	S1152	K1156T	1156	Missense	distal	4	no	20.622	19.774	EPSD	ICGC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	Q01959	SLC6A3	P17252	PRKCA	S2	G9R	9	Missense	distal	7	no	18.203	18.227	EPSD	ICGC	16.704	Up-regulation
AGC_PKC_PKCa_PRKCA_ST	Q01959	SLC6A3	P17252	PRKCA	S2	S4R	4	Missense	proximal	2	no	18.203	22.823	EPSD	ICGC;COSMIC	16.704	Up-regulation
AGC_PKC_PKCa_PRKCA_ST	Q01959	SLC6A3	P17252	PRKCA	S7	G9R	9	Missense	proximal	2	no	16.496	21.741	PhosphoSitePlus;EPSD	ICGC	16.704	Gain
AGC_PKC_PKCa_PRKCA_ST	Q01959	SLC6A3	P17252	PRKCA	S7	S4R	4	Missense	distal	-3	no	16.496	19.366	PhosphoSitePlus;EPSD	ICGC;COSMIC	16.704	Gain
AGC_PKC_PKCa_PRKCA_ST	Q01959	SLC6A3	P17252	PRKCA	S12	G9R	9	Missense	distal	-3	no	15.927	19.189	EPSD;PhosphoSitePlus	ICGC	16.704	Gain
AGC_PKC_PKCa_PRKCA_ST	Q01959	SLC6A3	P17252	PRKCA	S53	V55M	55	Missense	proximal	2	no	16.344	16.911	EPSD	ICGC;COSMIC	16.704	Gain
AGC_PKC_PKCa_PRKCA_ST	Q01959	SLC6A3	P17252	PRKCA	S262	W256R	256	Missense	distal	-6	no	17.762	18.047	EPSD	ICGC	16.704	Up-regulation
AGC_PKC_PKCa_PRKCA_ST	Q01959	SLC6A3	P17252	PRKCA	S262	L255F	255	Missense	distal	-7	no	17.762	17.760	EPSD	ICGC;COSMIC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	O15350	TP73	P17252	PRKCA	S289	I294L	294	Missense	distal	5	no	19.811	19.814	EPSD	ICGC;COSMIC	16.704	Up-regulation
AGC_PKC_PKCa_PRKCA_ST	O15350	TP73	P17252	PRKCA	S326	G323R	323	Missense	distal	-3	no	19.187	22.449	EPSD	ICGC;COSMIC	16.704	Up-regulation
AGC_PKC_PKCa_PRKCA_ST	O15350	TP73	P17252	PRKCA	S326	K331N	331	Missense	distal	5	no	19.187	18.681	EPSD	ICGC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	O15350	TP73	P17252	PRKCA	S471	S471R	471	Missense	central	0	yes	17.254	0.000	EPSD	ICGC;COSMIC	16.704	Loss
AGC_PKC_PKCa_PRKCA_ST	O15350	TP73	P17252	PRKCA	S471	S474F	474	Missense	distal	3	no	17.254	16.741	EPSD	ICGC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	P06401	PGR	P17252	PRKCA	S162	S168Y	168	Missense	distal	6	no	17.409	17.427	EPSD	ICGC	16.704	Up-regulation
AGC_PKC_PKCa_PRKCA_ST	P06401	PGR	P17252	PRKCA	S162	L164I	164	Missense	proximal	2	no	17.409	17.364	EPSD	ICGC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	P06401	PGR	P17252	PRKCA	S190	L189M	189	Missense	proximal	-1	no	19.015	20.094	EPSD	ICGC	16.704	Up-regulation
AGC_PKC_PKCa_PRKCA_ST	P06401	PGR	P17252	PRKCA	S190	R193Q	193	Missense	distal	3	no	19.015	16.562	EPSD	ICGC;COSMIC	16.704	Loss
AGC_PKC_PKCa_PRKCA_ST	P06401	PGR	P17252	PRKCA	S190	K183N	183	Missense	distal	-7	no	19.015	19.010	EPSD	ICGC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	P06401	PGR	P17252	PRKCA	S276	E271D	271	Missense	distal	-5	no	17.207	17.129	EPSD	ICGC;COSMIC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	P06401	PGR	P17252	PRKCA	S276	F275L	275	Missense	proximal	-1	no	17.207	17.495	EPSD	ICGC;COSMIC	16.704	Up-regulation
AGC_PKC_PKCa_PRKCA_ST	P06401	PGR	P17252	PRKCA	S400	S400F	400	Missense	central	0	yes	17.185	0.000	PhosphoSitePlus	ICGC;COSMIC	16.704	Loss
AGC_PKC_PKCa_PRKCA_ST	Q8N556	AFAP1	P17252	PRKCA	S307	V302L	302	Missense	distal	-5	no	22.757	23.194	EPSD	ICGC;COSMIC	16.704	Up-regulation
AGC_PKC_PKCa_PRKCA_ST	Q8N556	AFAP1	P17252	PRKCA	S307	S308Y	308	Missense	proximal	1	no	22.757	23.568	EPSD	ICGC	16.704	Up-regulation
AGC_PKC_PKCa_PRKCA_ST	Q8N556	AFAP1	P17252	PRKCA	S307	E300K	300	Missense	distal	-7	no	22.757	22.765	EPSD	ICGC	16.704	Up-regulation
AGC_PKC_PKCa_PRKCA_ST	Q8N556	AFAP1	P17252	PRKCA	S308	V302L	302	Missense	distal	-6	no	17.992	18.041	EPSD	ICGC;COSMIC	16.704	Up-regulation
AGC_PKC_PKCa_PRKCA_ST	Q8N556	AFAP1	P17252	PRKCA	S308	S308Y	308	Missense	central	0	yes	17.992	0.000	EPSD	ICGC	16.704	Loss
AGC_PKC_PKCa_PRKCA_ST	Q8N556	AFAP1	P17252	PRKCA	S336	T337K	337	Missense	proximal	1	no	16.641	17.525	EPSD	ICGC	16.704	Gain
AGC_PKC_PKCa_PRKCA_ST	Q8N556	AFAP1	P17252	PRKCA	T487	N489K	489	Missense	proximal	2	no	11.775	16.724	EPSD	ICGC	16.704	Gain
AGC_PKC_PKCa_PRKCA_ST	Q8N556	AFAP1	P17252	PRKCA	S531	D538N	538	Missense	distal	7	no	16.713	16.687	EPSD	ICGC;GDSC	16.704	Loss
AGC_PKC_PKCa_PRKCA_ST	Q96T49	PPP1R16B	P17252	PRKCA	S56	R60L	60	Missense	distal	4	no	19.577	18.538	EPSD	ICGC;COSMIC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	Q96T49	PPP1R16B	P17252	PRKCA	S56	S56G	56	Missense	central	0	yes	19.577	0.000	EPSD	ICGC;COSMIC	16.704	Loss
AGC_PKC_PKCa_PRKCA_ST	Q96T49	PPP1R16B	P17252	PRKCA	S331	L326P	326	Missense	distal	-5	no	18.024	18.051	PhosphoSitePlus	ICGC	16.704	Up-regulation
AGC_PKC_PKCa_PRKCA_ST	Q96T49	PPP1R16B	P17252	PRKCA	S331	S330I	330	Missense	proximal	-1	no	18.024	16.741	PhosphoSitePlus	ICGC;COSMIC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	Q8TD43	TRPM4	P17252	PRKCA	S94	R92Q	92	Missense	proximal	-2	no	20.175	18.416	EPSD	ICGC;COSMIC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	Q8TD43	TRPM4	P17252	PRKCA	S255	L253M	253	Missense	proximal	-2	no	19.561	20.268	EPSD	ICGC;COSMIC	16.704	Up-regulation
AGC_PKC_PKCa_PRKCA_ST	Q8TD43	TRPM4	P17252	PRKCA	S255	R252H	252	Missense	distal	-3	no	19.561	15.705	EPSD	ICGC;COSMIC	16.704	Loss
AGC_PKC_PKCa_PRKCA_ST	Q8TD43	TRPM4	P17252	PRKCA	S255	R250C	250	Missense	distal	-5	no	19.561	18.885	EPSD	ICGC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	Q8TD43	TRPM4	P17252	PRKCA	S1098	Q1100H	1100	Missense	proximal	2	no	19.660	18.471	EPSD	ICGC;COSMIC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	Q8TD43	TRPM4	P17252	PRKCA	S1143	R1136H	1136	Missense	distal	-7	no	16.763	16.756	EPSD	ICGC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	Q969H0	FBXW7	P17252	PRKCA	S10	R12I	12	Missense	proximal	2	no	25.231	20.199	PhosphoSitePlus;EPSD	ICGC;COSMIC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	Q969H0	FBXW7	P17252	PRKCA	S18	R20I	20	Missense	proximal	2	no	20.808	15.776	EPSD;PhosphoSitePlus	ICGC;COSMIC	16.704	Loss
AGC_PKC_PKCa_PRKCA_ST	Q969H0	FBXW7	P17252	PRKCA	S18	R12I	12	Missense	distal	-6	no	20.808	20.638	EPSD;PhosphoSitePlus	ICGC;COSMIC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	Q969H0	FBXW7	P17252	PRKCA	S18	P23S	23	Missense	distal	5	no	20.808	20.648	EPSD;PhosphoSitePlus	ICGC;COSMIC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	Q969H0	FBXW7	P17252	PRKCA	S227	I225M	225	Missense	proximal	-2	no	19.658	21.265	EPSD	ICGC	16.704	Up-regulation
AGC_PKC_PKCa_PRKCA_ST	Q969H0	FBXW7	P17252	PRKCA	S227	R223S	223	Missense	distal	-4	no	19.658	19.465	EPSD	ICGC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	Q969H0	FBXW7	P17252	PRKCA	S227	T226I	226	Missense	proximal	-1	no	19.658	18.753	EPSD	ICGC;GDSC;CCLE	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	Q969H0	FBXW7	P17252	PRKCA	S227	R224Q	224	Missense	distal	-3	no	19.658	16.801	EPSD	ICGC;COSMIC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	P11473	VDR	P17252	PRKCA	S7	T8I	8	Missense	proximal	1	no	16.584	17.920	EPSD	ICGC;COSMIC	16.704	Gain
AGC_PKC_PKCa_PRKCA_ST	P11473	VDR	P17252	PRKCA	S7	S9R	9	Missense	proximal	2	no	16.584	21.204	EPSD	ICGC	16.704	Gain
AGC_PKC_PKCa_PRKCA_ST	P11473	VDR	P17252	PRKCA	S7	P11S	11	Missense	distal	4	no	16.584	16.784	EPSD	ICGC;COSMIC	16.704	Gain
AGC_PKC_PKCa_PRKCA_ST	P11473	VDR	P17252	PRKCA	S7	A5V	5	Missense	proximal	-2	no	16.584	16.828	EPSD	ICGC	16.704	Gain
AGC_PKC_PKCa_PRKCA_ST	Q9NPC2	KCNK9	P17252	PRKCA	T134	T134N	134	Missense	central	0	yes	17.526	0.000	EPSD	ICGC;COSMIC	16.704	Loss
AGC_PKC_PKCa_PRKCA_ST	Q9NPC2	KCNK9	P17252	PRKCA	T134	R137C	137	Missense	distal	3	no	17.526	14.908	EPSD	ICGC	16.704	Loss
AGC_PKC_PKCa_PRKCA_ST	Q9NPC2	KCNK9	P17252	PRKCA	T134	T134P	134	Missense	central	0	yes	17.526	0.000	EPSD	ICGC;COSMIC	16.704	Loss
AGC_PKC_PKCa_PRKCA_ST	Q9NPC2	KCNK9	P17252	PRKCA	T134	S127R	127	Missense	distal	-7	no	17.526	17.532	EPSD	ICGC	16.704	Up-regulation
AGC_PKC_PKCa_PRKCA_ST	Q9NPC2	KCNK9	P17252	PRKCA	S317	P314Q	314	Missense	distal	-3	no	15.824	16.815	EPSD	ICGC	16.704	Gain
AGC_PKC_PKCa_PRKCA_ST	Q9NPC2	KCNK9	P17252	PRKCA	T341	T341K	341	Missense	central	0	yes	17.927	0.000	PhosphoSitePlus	ICGC	16.704	Loss
AGC_PKC_PKCa_PRKCA_ST	Q9NPC2	KCNK9	P17252	PRKCA	T341	P339T	339	Missense	proximal	-2	no	17.927	18.075	PhosphoSitePlus	ICGC	16.704	Up-regulation
AGC_PKC_PKCa_PRKCA_ST	Q9NPC2	KCNK9	P17252	PRKCA	T341	S340R	340	Missense	proximal	-1	no	17.927	18.314	PhosphoSitePlus	ICGC;COSMIC	16.704	Up-regulation
AGC_PKC_PKCa_PRKCA_ST	Q9NPC2	KCNK9	P17252	PRKCA	T341	L346I	346	Missense	distal	5	no	17.927	17.924	PhosphoSitePlus	ICGC;COSMIC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	Q9NPC2	KCNK9	P17252	PRKCA	T341	S345R	345	Missense	distal	4	no	17.927	18.173	PhosphoSitePlus	ICGC	16.704	Up-regulation
AGC_PKC_PKCa_PRKCA_ST	Q9NPC2	KCNK9	P17252	PRKCA	S373	R370C	370	Missense	distal	-3	no	16.743	14.004	EPSD	ICGC;COSMIC	16.704	Loss
AGC_PKC_PKCa_PRKCA_ST	Q12959	DLG1	P17252	PRKCA	S23	S20L	20	Missense	distal	-3	no	18.137	16.651	EPSD	ICGC;COSMIC	16.704	Loss
AGC_PKC_PKCa_PRKCA_ST	Q12959	DLG1	P17252	PRKCA	S100	S102R	102	Missense	proximal	2	no	12.802	17.422	EPSD	ICGC	16.704	Gain
AGC_PKC_PKCa_PRKCA_ST	Q12959	DLG1	P17252	PRKCA	S579	Y585H	585	Missense	distal	6	no	21.263	21.238	EPSD	ICGC;COSMIC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	Q12959	DLG1	P17252	PRKCA	S583	Y585H	585	Missense	proximal	2	no	18.178	17.649	EPSD	ICGC;COSMIC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	Q12959	DLG1	P17252	PRKCA	T657	T664K	664	Missense	distal	7	no	20.821	20.911	PhosphoSitePlus	ICGC	16.704	Up-regulation
AGC_PKC_PKCa_PRKCA_ST	Q12959	DLG1	P17252	PRKCA	S662	T664K	664	Missense	proximal	2	no	15.494	19.883	EPSD	ICGC	16.704	Gain
AGC_PKC_PKCa_PRKCA_ST	Q12959	DLG1	P17252	PRKCA	S692	S691Y	691	Missense	proximal	-1	no	18.890	18.440	EPSD	ICGC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	Q5NUL3	FFAR4	P17252	PRKCA	S253	A252S	252	Missense	proximal	-1	no	19.689	20.248	EPSD	ICGC;COSMIC	16.704	Up-regulation
AGC_PKC_PKCa_PRKCA_ST	P41180	CASR	P17252	PRKCA	S342	H344Q	344	Missense	proximal	2	no	16.182	17.371	EPSD	ICGC;COSMIC	16.704	Gain
AGC_PKC_PKCa_PRKCA_ST	P41180	CASR	P17252	PRKCA	S794	P798Q	798	Missense	distal	4	no	16.511	16.739	EPSD	ICGC;COSMIC	16.704	Gain
AGC_PKC_PKCa_PRKCA_ST	P41180	CASR	P17252	PRKCA	S794	F789L	789	Missense	distal	-5	no	16.511	16.707	EPSD	ICGC;COSMIC	16.704	Gain
AGC_PKC_PKCa_PRKCA_ST	P41180	CASR	P17252	PRKCA	S794	E799K	799	Missense	distal	5	no	16.511	16.925	EPSD	ICGC;COSMIC	16.704	Gain
AGC_PKC_PKCa_PRKCA_ST	P41180	CASR	P17252	PRKCA	T888	V894I	894	Missense	distal	6	no	17.986	18.041	PhosphoSitePlus	ICGC;COSMIC	16.704	Up-regulation
AGC_PKC_PKCa_PRKCA_ST	P41180	CASR	P17252	PRKCA	T888	R886Q	886	Missense	proximal	-2	no	17.986	16.227	PhosphoSitePlus	ICGC;COSMIC	16.704	Loss
AGC_PKC_PKCa_PRKCA_ST	P41180	CASR	P17252	PRKCA	T888	R886W	886	Missense	proximal	-2	no	17.986	15.988	PhosphoSitePlus	ICGC;COSMIC	16.704	Loss
AGC_PKC_PKCa_PRKCA_ST	P41180	CASR	P17252	PRKCA	T888	A884S	884	Missense	distal	-4	no	17.986	17.899	PhosphoSitePlus	ICGC;COSMIC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	P41180	CASR	P17252	PRKCA	T888	K882N	882	Missense	distal	-6	no	17.986	17.862	PhosphoSitePlus	ICGC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	P41180	CASR	P17252	PRKCA	T888	R891L	891	Missense	distal	3	no	17.986	15.748	PhosphoSitePlus	ICGC;COSMIC	16.704	Loss
AGC_PKC_PKCa_PRKCA_ST	P41180	CASR	P17252	PRKCA	T888	A887G	887	Missense	proximal	-1	no	17.986	18.793	PhosphoSitePlus	ICGC;COSMIC	16.704	Up-regulation
AGC_PKC_PKCa_PRKCA_ST	P41180	CASR	P17252	PRKCA	T888	R891P	891	Missense	distal	3	no	17.986	16.455	PhosphoSitePlus	ICGC;COSMIC	16.704	Loss
AGC_PKC_PKCa_PRKCA_ST	P41180	CASR	P17252	PRKCA	T888	R891G	891	Missense	distal	3	no	17.986	17.346	PhosphoSitePlus	ICGC;COSMIC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	P41180	CASR	P17252	PRKCA	T888	R890C	890	Missense	proximal	2	no	17.986	13.636	PhosphoSitePlus	ICGC;COSMIC;GDSC;CCLE	16.704	Loss
AGC_PKC_PKCa_PRKCA_ST	P41180	CASR	P17252	PRKCA	T888	T888M	888	Missense	central	0	yes	17.986	0.000	PhosphoSitePlus	ICGC;COSMIC	16.704	Loss
AGC_PKC_PKCa_PRKCA_ST	P41180	CASR	P17252	PRKCA	T888	R890H	890	Missense	proximal	2	no	17.986	12.962	PhosphoSitePlus	ICGC;COSMIC	16.704	Loss
AGC_PKC_PKCa_PRKCA_ST	P41180	CASR	P17252	PRKCA	T888	R891H	891	Missense	distal	3	no	17.986	17.274	PhosphoSitePlus	ICGC;COSMIC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	P41180	CASR	P17252	PRKCA	S895	R896H	896	Missense	proximal	1	no	19.647	18.834	EPSD	ICGC;COSMIC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	P41180	CASR	P17252	PRKCA	S895	V894I	894	Missense	proximal	-1	no	19.647	19.826	EPSD	ICGC;COSMIC	16.704	Up-regulation
AGC_PKC_PKCa_PRKCA_ST	P41180	CASR	P17252	PRKCA	S895	R896C	896	Missense	proximal	1	no	19.647	16.811	EPSD	ICGC;COSMIC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	P41180	CASR	P17252	PRKCA	S895	R891L	891	Missense	distal	-4	no	19.647	19.023	EPSD	ICGC;COSMIC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	P41180	CASR	P17252	PRKCA	S895	R891P	891	Missense	distal	-4	no	19.647	19.282	EPSD	ICGC;COSMIC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	P41180	CASR	P17252	PRKCA	S895	L902V	902	Missense	distal	7	no	19.647	19.588	EPSD	ICGC;COSMIC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	P41180	CASR	P17252	PRKCA	S895	R891G	891	Missense	distal	-4	no	19.647	19.545	EPSD	ICGC;COSMIC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	P41180	CASR	P17252	PRKCA	S895	R890C	890	Missense	distal	-5	no	19.647	18.971	EPSD	ICGC;COSMIC;GDSC;CCLE	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	P41180	CASR	P17252	PRKCA	S895	T888M	888	Missense	distal	-7	no	19.647	19.652	EPSD	ICGC;COSMIC	16.704	Up-regulation
AGC_PKC_PKCa_PRKCA_ST	P41180	CASR	P17252	PRKCA	S895	R890H	890	Missense	distal	-5	no	19.647	19.291	EPSD	ICGC;COSMIC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	P41180	CASR	P17252	PRKCA	S895	R891H	891	Missense	distal	-4	no	19.647	19.073	EPSD	ICGC;COSMIC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	P41180	CASR	P17252	PRKCA	S899	R896H	896	Missense	distal	-3	no	17.285	13.428	EPSD	ICGC;COSMIC	16.704	Loss
AGC_PKC_PKCa_PRKCA_ST	P41180	CASR	P17252	PRKCA	S899	V894I	894	Missense	distal	-5	no	17.285	17.277	EPSD	ICGC;COSMIC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	P41180	CASR	P17252	PRKCA	S899	R896C	896	Missense	distal	-3	no	17.285	14.545	EPSD	ICGC;COSMIC	16.704	Loss
AGC_PKC_PKCa_PRKCA_ST	P41180	CASR	P17252	PRKCA	S899	L902V	902	Missense	distal	3	no	17.285	17.668	EPSD	ICGC;COSMIC	16.704	Up-regulation
AGC_PKC_PKCa_PRKCA_ST	P41180	CASR	P17252	PRKCA	S899	G903R	903	Missense	distal	4	no	17.285	17.888	EPSD	ICGC;COSMIC	16.704	Up-regulation
AGC_PKC_PKCa_PRKCA_ST	P41180	CASR	P17252	PRKCA	S900	R896H	896	Missense	distal	-4	no	17.164	16.590	EPSD	ICGC;COSMIC	16.704	Loss
AGC_PKC_PKCa_PRKCA_ST	P41180	CASR	P17252	PRKCA	S900	V894I	894	Missense	distal	-6	no	17.164	17.181	EPSD	ICGC;COSMIC	16.704	Up-regulation
AGC_PKC_PKCa_PRKCA_ST	P41180	CASR	P17252	PRKCA	S900	R896C	896	Missense	distal	-4	no	17.164	15.821	EPSD	ICGC;COSMIC	16.704	Loss
AGC_PKC_PKCa_PRKCA_ST	P41180	CASR	P17252	PRKCA	S900	L902V	902	Missense	proximal	2	no	17.164	17.137	EPSD	ICGC;COSMIC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	P41180	CASR	P17252	PRKCA	S900	G907E	907	Missense	distal	7	no	17.164	17.093	EPSD	ICGC;COSMIC;CCLE	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	P41180	CASR	P17252	PRKCA	S900	G903R	903	Missense	distal	3	no	17.164	17.804	EPSD	ICGC;COSMIC	16.704	Up-regulation
AGC_PKC_PKCa_PRKCA_ST	P41180	CASR	P17252	PRKCA	S901	R896H	896	Missense	distal	-5	no	16.908	16.552	EPSD	ICGC;COSMIC	16.704	Loss
AGC_PKC_PKCa_PRKCA_ST	P41180	CASR	P17252	PRKCA	S901	V894I	894	Missense	distal	-7	no	16.908	16.907	EPSD	ICGC;COSMIC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	P41180	CASR	P17252	PRKCA	S901	R896C	896	Missense	distal	-5	no	16.908	16.232	EPSD	ICGC;COSMIC	16.704	Loss
AGC_PKC_PKCa_PRKCA_ST	P41180	CASR	P17252	PRKCA	S901	L902V	902	Missense	proximal	1	no	16.908	17.033	EPSD	ICGC;COSMIC	16.704	Up-regulation
AGC_PKC_PKCa_PRKCA_ST	P41180	CASR	P17252	PRKCA	S901	G907E	907	Missense	distal	6	no	16.908	16.951	EPSD	ICGC;COSMIC;CCLE	16.704	Up-regulation
AGC_PKC_PKCa_PRKCA_ST	P41180	CASR	P17252	PRKCA	S901	G903R	903	Missense	proximal	2	no	16.908	22.153	EPSD	ICGC;COSMIC	16.704	Up-regulation
AGC_PKC_PKCa_PRKCA_ST	P41180	CASR	P17252	PRKCA	S997	E999K	999	Missense	proximal	2	no	13.171	18.450	EPSD	ICGC;COSMIC	16.704	Gain
AGC_PKC_PKCa_PRKCA_ST	Q04206	RELA	P17252	PRKCA	S131	E127Q	127	Missense	distal	-4	no	16.531	16.850	EPSD	ICGC;COSMIC	16.704	Gain
AGC_PKC_PKCa_PRKCA_ST	Q04206	RELA	P17252	PRKCA	S238	A235S	235	Missense	distal	-3	no	15.545	17.124	EPSD	ICGC;COSMIC	16.704	Gain
AGC_PKC_PKCa_PRKCA_ST	Q04206	RELA	P17252	PRKCA	S276	D277E	277	Missense	proximal	1	no	20.996	21.029	EPSD	ICGC;COSMIC	16.704	Up-regulation
AGC_PKC_PKCa_PRKCA_ST	Q99623	PHB2	P17252	PRKCA	S39	A33S	33	Missense	distal	-6	no	17.637	17.674	PhosphoSitePlus	ICGC	16.704	Up-regulation
AGC_PKC_PKCa_PRKCA_ST	Q99623	PHB2	P17252	PRKCA	S105	L109F	109	Missense	distal	4	no	16.893	17.324	EPSD	ICGC;COSMIC	16.704	Up-regulation
AGC_PKC_PKCa_PRKCA_ST	Q99623	PHB2	P17252	PRKCA	T169	A172S	172	Missense	distal	3	no	19.559	19.765	EPSD	ICGC;COSMIC	16.704	Up-regulation
AGC_PKC_PKCa_PRKCA_ST	P16070	CD44	P17252	PRKCA	S672	V670M	670	Missense	proximal	-2	no	18.340	19.201	PhosphoSitePlus	ICGC	16.704	Up-regulation
AGC_PKC_PKCa_PRKCA_ST	O14939	PLD2	P17252	PRKCA	T99	D95G	95	Missense	distal	-4	no	16.543	17.312	EPSD	ICGC;COSMIC	16.704	Gain
AGC_PKC_PKCa_PRKCA_ST	O14939	PLD2	P17252	PRKCA	T100	D95G	95	Missense	distal	-5	no	17.878	17.972	EPSD	ICGC;COSMIC	16.704	Up-regulation
AGC_PKC_PKCa_PRKCA_ST	O14939	PLD2	P17252	PRKCA	S155	R149P	149	Missense	distal	-6	no	18.533	18.428	EPSD	ICGC;COSMIC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	O14939	PLD2	P17252	PRKCA	S213	G207R	207	Missense	distal	-6	no	19.804	19.912	EPSD	ICGC;COSMIC	16.704	Up-regulation
AGC_PKC_PKCa_PRKCA_ST	O14939	PLD2	P17252	PRKCA	S213	R210W	210	Missense	distal	-3	no	19.804	17.450	EPSD	ICGC;COSMIC;GDSC;CCLE	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	O14939	PLD2	P17252	PRKCA	S213	R217C	217	Missense	distal	4	no	19.804	18.403	EPSD	ICGC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	O14939	PLD2	P17252	PRKCA	T274	V280M	280	Missense	distal	6	no	17.364	17.452	EPSD	ICGC;COSMIC	16.704	Up-regulation
AGC_PKC_PKCa_PRKCA_ST	O14939	PLD2	P17252	PRKCA	S416	G414D	414	Missense	proximal	-2	no	19.446	18.899	EPSD	ICGC;COSMIC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	O14939	PLD2	P17252	PRKCA	T488	P489L	489	Missense	proximal	1	no	16.907	17.334	EPSD	ICGC;COSMIC	16.704	Up-regulation
AGC_PKC_PKCa_PRKCA_ST	O14939	PLD2	P17252	PRKCA	T488	P489S	489	Missense	proximal	1	no	16.907	16.508	EPSD	ICGC;COSMIC;GDSC;CCLE	16.704	Loss
AGC_PKC_PKCa_PRKCA_ST	O14939	PLD2	P17252	PRKCA	S814	G821S	821	Missense	distal	7	no	18.723	18.701	EPSD	ICGC;COSMIC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	Q5JVS0	HABP4	P17252	PRKCA	T121	E126D	126	Missense	distal	5	no	18.879	18.787	EPSD	ICGC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	Q5JVS0	HABP4	P17252	PRKCA	T121	R123I	123	Missense	proximal	2	no	18.879	13.847	EPSD	ICGC;COSMIC	16.704	Loss
AGC_PKC_PKCa_PRKCA_ST	Q5JVS0	HABP4	P17252	PRKCA	T375	R376P	376	Missense	proximal	1	no	18.122	17.348	PhosphoSitePlus;EPSD	ICGC;COSMIC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	Q9BZL6	PRKD2	P17252	PRKCA	S206	G210V	210	Missense	distal	4	no	18.452	17.488	EPSD	ICGC;COSMIC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	Q9BZL6	PRKD2	P17252	PRKCA	S529	A528E	528	Missense	proximal	-1	no	16.922	17.499	EPSD	ICGC	16.704	Up-regulation
AGC_PKC_PKCa_PRKCA_ST	Q13002	GRIK2	P17252	PRKCA	S416	N412H	412	Missense	distal	-4	no	21.070	21.018	EPSD	ICGC;COSMIC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	Q13002	GRIK2	P17252	PRKCA	S416	K418T	418	Missense	proximal	2	no	21.070	16.681	EPSD	ICGC	16.704	Loss
AGC_PKC_PKCa_PRKCA_ST	Q13002	GRIK2	P17252	PRKCA	S416	A422T	422	Missense	distal	6	no	21.070	20.992	EPSD	ICGC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	Q13002	GRIK2	P17252	PRKCA	S666	E665D	665	Missense	proximal	-1	no	18.976	18.462	EPSD	ICGC;COSMIC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	Q13002	GRIK2	P17252	PRKCA	S666	R663L	663	Missense	distal	-3	no	18.976	14.621	EPSD	ICGC	16.704	Loss
AGC_PKC_PKCa_PRKCA_ST	Q13002	GRIK2	P17252	PRKCA	S666	E662K	662	Missense	distal	-4	no	18.976	19.707	EPSD	ICGC;CCLE	16.704	Up-regulation
AGC_PKC_PKCa_PRKCA_ST	Q13002	GRIK2	P17252	PRKCA	S697	S700A	700	Missense	distal	3	no	17.665	17.458	EPSD	ICGC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	Q13002	GRIK2	P17252	PRKCA	S697	D703E	703	Missense	distal	6	no	17.665	17.648	EPSD	ICGC;COSMIC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	Q13002	GRIK2	P17252	PRKCA	S715	Q714H	714	Missense	proximal	-1	no	20.252	20.746	EPSD	ICGC	16.704	Up-regulation
AGC_PKC_PKCa_PRKCA_ST	Q13002	GRIK2	P17252	PRKCA	S846	E841K	841	Missense	distal	-5	no	19.804	20.098	EPSD	ICGC	16.704	Up-regulation
AGC_PKC_PKCa_PRKCA_ST	Q13002	GRIK2	P17252	PRKCA	S846	L843F	843	Missense	distal	-3	no	19.804	21.539	EPSD	ICGC;COSMIC	16.704	Up-regulation
AGC_PKC_PKCa_PRKCA_ST	Q13002	GRIK2	P17252	PRKCA	S846	V839L	839	Missense	distal	-7	no	19.804	19.806	EPSD	ICGC;COSMIC	16.704	Up-regulation
AGC_PKC_PKCa_PRKCA_ST	Q13002	GRIK2	P17252	PRKCA	S868	R866K	866	Missense	proximal	-2	no	22.309	20.681	PhosphoSitePlus	ICGC;COSMIC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	Q13002	GRIK2	P17252	PRKCA	S868	E863D	863	Missense	distal	-5	no	22.309	22.231	PhosphoSitePlus	ICGC;COSMIC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	Q13002	GRIK2	P17252	PRKCA	S868	C871F	871	Missense	distal	3	no	22.309	23.023	PhosphoSitePlus	ICGC	16.704	Up-regulation
AGC_PKC_PKCa_PRKCA_ST	Q13002	GRIK2	P17252	PRKCA	S868	L875V	875	Missense	distal	7	no	22.309	22.250	PhosphoSitePlus	ICGC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	Q96C90	PPP1R14B	P17252	PRKCA	T57	R52S	52	Missense	distal	-5	no	16.993	16.566	PhosphoSitePlus	ICGC	16.704	Loss
AGC_PKC_PKCa_PRKCA_ST	Q09472	EP300	P17252	PRKCA	S12	P8S	8	Missense	distal	-4	no	22.214	22.386	EPSD	ICGC;COSMIC	16.704	Up-regulation
AGC_PKC_PKCa_PRKCA_ST	Q09472	EP300	P17252	PRKCA	S12	S12P	12	Missense	central	0	yes	22.214	0.000	EPSD	ICGC;COSMIC	16.704	Loss
AGC_PKC_PKCa_PRKCA_ST	Q09472	EP300	P17252	PRKCA	S20	S24L	24	Missense	distal	4	no	16.832	16.039	EPSD	ICGC;COSMIC	16.704	Loss
AGC_PKC_PKCa_PRKCA_ST	Q09472	EP300	P17252	PRKCA	S384	V390G	390	Missense	distal	6	no	16.999	17.010	EPSD	ICGC;COSMIC	16.704	Up-regulation
AGC_PKC_PKCa_PRKCA_ST	Q09472	EP300	P17252	PRKCA	S384	H378N	378	Missense	distal	-6	no	16.999	16.937	EPSD	ICGC;COSMIC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	Q09472	EP300	P17252	PRKCA	S395	I399V	399	Missense	distal	4	no	16.913	17.036	EPSD	ICGC;COSMIC	16.704	Up-regulation
AGC_PKC_PKCa_PRKCA_ST	Q09472	EP300	P17252	PRKCA	S395	V390G	390	Missense	distal	-5	no	16.913	17.187	EPSD	ICGC;COSMIC	16.704	Up-regulation
AGC_PKC_PKCa_PRKCA_ST	Q09472	EP300	P17252	PRKCA	S1044	P1039S	1039	Missense	distal	-5	no	17.120	16.795	EPSD	ICGC;COSMIC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	Q09472	EP300	P17252	PRKCA	T1135	A1128T	1128	Missense	distal	-7	no	18.975	18.970	EPSD	ICGC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	Q09472	EP300	P17252	PRKCA	T1135	Y1131N	1131	Missense	distal	-4	no	18.975	18.838	EPSD	ICGC;COSMIC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	Q09472	EP300	P17252	PRKCA	S1193	R1187H	1187	Missense	distal	-6	no	17.037	16.970	EPSD	ICGC;COSMIC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	Q09472	EP300	P17252	PRKCA	S1730	D1729N	1729	Missense	proximal	-1	no	18.150	18.488	EPSD	ICGC;COSMIC	16.704	Up-regulation
AGC_PKC_PKCa_PRKCA_ST	Q09472	EP300	P17252	PRKCA	S1734	D1729N	1729	Missense	distal	-5	no	21.175	21.204	EPSD	ICGC;COSMIC	16.704	Up-regulation
AGC_PKC_PKCa_PRKCA_ST	Q09472	EP300	P17252	PRKCA	S1734	Q1740K	1740	Missense	distal	6	no	21.175	21.285	EPSD	ICGC;COSMIC	16.704	Up-regulation
AGC_PKC_PKCa_PRKCA_ST	Q09472	EP300	P17252	PRKCA	S1834	R1829H	1829	Missense	distal	-5	no	20.807	20.452	EPSD	ICGC;COSMIC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	Q09472	EP300	P17252	PRKCA	S1834	A1833T	1833	Missense	proximal	-1	no	20.807	20.988	EPSD	ICGC;COSMIC	16.704	Up-regulation
AGC_PKC_PKCa_PRKCA_ST	Q09472	EP300	P17252	PRKCA	S1834	R1829L	1829	Missense	distal	-5	no	20.807	20.679	EPSD	ICGC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	Q09472	EP300	P17252	PRKCA	S1834	R1831S	1831	Missense	distal	-3	no	20.807	17.937	EPSD	ICGC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	Q8N0W4	NLGN4X	P17252	PRKCA	T249	G256R	256	Missense	distal	7	no	17.149	17.174	EPSD	ICGC;COSMIC	16.704	Up-regulation
AGC_PKC_PKCa_PRKCA_ST	Q8N0W4	NLGN4X	P17252	PRKCA	T249	G242S	242	Missense	distal	-7	no	17.149	17.154	EPSD	ICGC	16.704	Up-regulation
AGC_PKC_PKCa_PRKCA_ST	Q8N0W4	NLGN4X	P17252	PRKCA	T249	A255D	255	Missense	distal	6	no	17.149	17.102	EPSD	ICGC;COSMIC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	Q8N0W4	NLGN4X	P17252	PRKCA	T636	P629S	629	Missense	distal	-7	no	17.602	17.605	EPSD	ICGC;COSMIC	16.704	Up-regulation
AGC_PKC_PKCa_PRKCA_ST	Q8N0W4	NLGN4X	P17252	PRKCA	T636	A640E	640	Missense	distal	4	no	17.602	17.464	EPSD	ICGC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	Q8N0W4	NLGN4X	P17252	PRKCA	T636	R638C	638	Missense	proximal	2	no	17.602	13.252	EPSD	ICGC;COSMIC	16.704	Loss
AGC_PKC_PKCa_PRKCA_ST	Q8N0W4	NLGN4X	P17252	PRKCA	T636	R638H	638	Missense	proximal	2	no	17.602	12.578	EPSD	ICGC;COSMIC	16.704	Loss
AGC_PKC_PKCa_PRKCA_ST	Q8N0W4	NLGN4X	P17252	PRKCA	T707	R710H	710	Missense	distal	3	no	21.286	20.574	PhosphoSitePlus	ICGC;COSMIC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	Q8N0W4	NLGN4X	P17252	PRKCA	S712	N716K	716	Missense	distal	4	no	22.370	23.497	EPSD	ICGC	16.704	Up-regulation
AGC_PKC_PKCa_PRKCA_ST	Q8N0W4	NLGN4X	P17252	PRKCA	S712	R710H	710	Missense	proximal	-2	no	22.370	17.816	EPSD	ICGC;COSMIC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	Q8N0W4	NLGN4X	P17252	PRKCA	S745	Q747K	747	Missense	proximal	2	no	13.599	17.012	EPSD	ICGC;COSMIC	16.704	Gain
AGC_PKC_PKCa_PRKCA_ST	P49407	ARRB1	P17252	PRKCA	S193	R188K	188	Missense	distal	-5	no	17.818	17.805	EPSD	ICGC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	P49407	ARRB1	P17252	PRKCA	S193	P196H	196	Missense	distal	3	no	17.818	18.637	EPSD	ICGC	16.704	Up-regulation
AGC_PKC_PKCa_PRKCA_ST	P49407	ARRB1	P17252	PRKCA	S193	T187N	187	Missense	distal	-6	no	17.818	17.887	EPSD	ICGC	16.704	Up-regulation
AGC_PKC_PKCa_PRKCA_ST	P49407	ARRB1	P17252	PRKCA	S193	D194N	194	Missense	proximal	1	no	17.818	18.291	EPSD	ICGC;COSMIC	16.704	Up-regulation
AGC_PKC_PKCa_PRKCA_ST	P49407	ARRB1	P17252	PRKCA	S193	R188S	188	Missense	distal	-5	no	17.818	17.392	EPSD	ICGC;COSMIC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	P08567	PLEK	P17252	PRKCA	S16	T20M	20	Missense	distal	4	no	18.941	19.422	EPSD	ICGC;COSMIC	16.704	Up-regulation
AGC_PKC_PKCa_PRKCA_ST	P08567	PLEK	P17252	PRKCA	S16	P23H	23	Missense	distal	7	no	18.941	18.879	EPSD	ICGC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	P08567	PLEK	P17252	PRKCA	S113	R116M	116	Missense	distal	3	no	22.977	21.708	PhosphoSitePlus;EPSD	ICGC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	P08567	PLEK	P17252	PRKCA	T114	R116M	116	Missense	proximal	2	no	21.199	16.751	EPSD	ICGC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	P08567	PLEK	P17252	PRKCA	S117	R116M	116	Missense	proximal	-1	no	22.507	22.779	EPSD;PhosphoSitePlus	ICGC	16.704	Up-regulation
AGC_PKC_PKCa_PRKCA_ST	P08567	PLEK	P17252	PRKCA	S132	G127C	127	Missense	distal	-5	no	17.855	17.469	EPSD	ICGC;COSMIC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	P08567	PLEK	P17252	PRKCA	S132	L131S	131	Missense	proximal	-1	no	17.855	18.274	EPSD	ICGC;COSMIC	16.704	Up-regulation
AGC_PKC_PKCa_PRKCA_ST	P08567	PLEK	P17252	PRKCA	T136	I140R	140	Missense	distal	4	no	16.674	18.364	EPSD	ICGC;COSMIC	16.704	Gain
AGC_PKC_PKCa_PRKCA_ST	O60500	NPHS1	P17252	PRKCA	T633	L630F	630	Missense	distal	-3	no	15.721	17.456	EPSD	ICGC	16.704	Gain
AGC_PKC_PKCa_PRKCA_ST	P09693	CD3G	P17252	PRKCA	S145	R143L	143	Missense	proximal	-2	no	17.931	15.243	EPSD	ICGC	16.704	Loss
AGC_PKC_PKCa_PRKCA_ST	P09693	CD3G	P17252	PRKCA	S145	Q144H	144	Missense	proximal	-1	no	17.931	18.426	EPSD	ICGC	16.704	Up-regulation
AGC_PKC_PKCa_PRKCA_ST	P09693	CD3G	P17252	PRKCA	S145	D140N	140	Missense	distal	-5	no	17.931	17.961	EPSD	ICGC;COSMIC	16.704	Up-regulation
AGC_PKC_PKCa_PRKCA_ST	P09693	CD3G	P17252	PRKCA	S145	S145L	145	Missense	central	0	yes	17.931	0.000	EPSD	ICGC	16.704	Loss
AGC_PKC_PKCa_PRKCA_ST	P09693	CD3G	P17252	PRKCA	S145	G141V	141	Missense	distal	-4	no	17.931	17.368	EPSD	ICGC;COSMIC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	P09693	CD3G	P17252	PRKCA	S148	R143L	143	Missense	distal	-5	no	20.548	20.420	PhosphoSitePlus	ICGC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	P09693	CD3G	P17252	PRKCA	S148	Q144H	144	Missense	distal	-4	no	20.548	20.351	PhosphoSitePlus	ICGC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	P09693	CD3G	P17252	PRKCA	S148	S145L	145	Missense	distal	-3	no	20.548	19.062	PhosphoSitePlus	ICGC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	P09693	CD3G	P17252	PRKCA	S148	G141V	141	Missense	distal	-7	no	20.548	20.544	PhosphoSitePlus	ICGC;COSMIC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	Q16875	PFKFB3	P17252	PRKCA	S273	R274W	274	Missense	proximal	1	no	17.002	16.278	EPSD	ICGC;COSMIC	16.704	Loss
AGC_PKC_PKCa_PRKCA_ST	P41091	EIF2S3	P17252	PRKCA	S418	G425C	425	Missense	distal	7	no	17.865	17.666	EPSD	ICGC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	P41091	EIF2S3	P17252	PRKCA	S418	A422S	422	Missense	distal	4	no	17.865	17.849	EPSD	ICGC;COSMIC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	P41091	EIF2S3	P17252	PRKCA	S418	D423Y	423	Missense	distal	5	no	17.865	18.112	EPSD	ICGC;COSMIC	16.704	Up-regulation
AGC_PKC_PKCa_PRKCA_ST	P41091	EIF2S3	P17252	PRKCA	S444	E448Q	448	Missense	distal	4	no	17.904	18.054	EPSD	ICGC;COSMIC	16.704	Up-regulation
AGC_PKC_PKCa_PRKCA_ST	P41091	EIF2S3	P17252	PRKCA	S444	L443I	443	Missense	proximal	-1	no	17.904	17.040	EPSD	ICGC;COSMIC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	Q13418	ILK	P17252	PRKCA	S228	D226E	226	Missense	proximal	-2	no	20.836	20.128	EPSD	ICGC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	Q13418	ILK	P17252	PRKCA	T229	D226E	226	Missense	distal	-3	no	17.591	17.695	EPSD	ICGC	16.704	Up-regulation
AGC_PKC_PKCa_PRKCA_ST	Q13769	THOC5	P17252	PRKCA	S2	R9Q	9	Missense	distal	7	no	17.083	17.079	EPSD	ICGC;COSMIC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	Q13769	THOC5	P17252	PRKCA	S2	S6R	6	Missense	distal	4	no	17.083	17.329	EPSD	ICGC	16.704	Up-regulation
AGC_PKC_PKCa_PRKCA_ST	Q13769	THOC5	P17252	PRKCA	S3	S6R	6	Missense	distal	3	no	16.502	17.893	EPSD	ICGC	16.704	Gain
AGC_PKC_PKCa_PRKCA_ST	Q13769	THOC5	P17252	PRKCA	S5	R9Q	9	Missense	distal	4	no	22.892	22.674	PhosphoSitePlus;EPSD	ICGC;COSMIC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	Q13769	THOC5	P17252	PRKCA	S5	S6R	6	Missense	proximal	1	no	22.892	24.065	PhosphoSitePlus;EPSD	ICGC	16.704	Up-regulation
AGC_PKC_PKCa_PRKCA_ST	Q13769	THOC5	P17252	PRKCA	S5	P11H	11	Missense	distal	6	no	22.892	22.853	PhosphoSitePlus;EPSD	ICGC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	Q13769	THOC5	P17252	PRKCA	S6	R9Q	9	Missense	distal	3	no	23.433	20.980	EPSD;PhosphoSitePlus	ICGC;COSMIC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	Q13769	THOC5	P17252	PRKCA	S6	S6R	6	Missense	central	0	yes	23.433	0.000	EPSD;PhosphoSitePlus	ICGC	16.704	Loss
AGC_PKC_PKCa_PRKCA_ST	Q13769	THOC5	P17252	PRKCA	S6	P11H	11	Missense	distal	5	no	23.433	23.156	EPSD;PhosphoSitePlus	ICGC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	Q13769	THOC5	P17252	PRKCA	S6	V13M	13	Missense	distal	7	no	23.433	23.500	EPSD;PhosphoSitePlus	ICGC	16.704	Up-regulation
AGC_PKC_PKCa_PRKCA_ST	Q13769	THOC5	P17252	PRKCA	S28	D29E	29	Missense	proximal	1	no	17.130	17.163	EPSD	ICGC	16.704	Up-regulation
AGC_PKC_PKCa_PRKCA_ST	Q13769	THOC5	P17252	PRKCA	S28	R27Q	27	Missense	proximal	-1	no	17.130	16.313	EPSD	ICGC;COSMIC	16.704	Loss
AGC_PKC_PKCa_PRKCA_ST	Q13769	THOC5	P17252	PRKCA	T322	R325W	325	Missense	distal	3	no	19.085	16.151	EPSD	ICGC	16.704	Loss
AGC_PKC_PKCa_PRKCA_ST	Q13769	THOC5	P17252	PRKCA	T328	R325W	325	Missense	distal	-3	no	18.431	16.077	EPSD	ICGC	16.704	Loss
AGC_PKC_PKCa_PRKCA_ST	Q12791	KCNMA1	P17252	PRKCA	S12	G13S	13	Missense	proximal	1	no	16.761	16.540	EPSD	ICGC;COSMIC;CCLE	16.704	Loss
AGC_PKC_PKCa_PRKCA_ST	Q12791	KCNMA1	P17252	PRKCA	S12	G10S	10	Missense	proximal	-2	no	16.761	16.331	EPSD	ICGC;COSMIC	16.704	Loss
AGC_PKC_PKCa_PRKCA_ST	Q12791	KCNMA1	P17252	PRKCA	S12	S12G	12	Missense	central	0	yes	16.761	0.000	EPSD	ICGC	16.704	Loss
AGC_PKC_PKCa_PRKCA_ST	Q12791	KCNMA1	P17252	PRKCA	S12	G7S	7	Missense	distal	-5	no	16.761	16.624	EPSD	ICGC	16.704	Loss
AGC_PKC_PKCa_PRKCA_ST	Q12791	KCNMA1	P17252	PRKCA	S511	I512T	512	Missense	proximal	1	no	21.348	20.013	EPSD	ICGC;COSMIC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	Q12791	KCNMA1	P17252	PRKCA	S511	P517L	517	Missense	distal	6	no	21.348	21.304	EPSD	ICGC;COSMIC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	Q12791	KCNMA1	P17252	PRKCA	S778	G773D	773	Missense	distal	-5	no	17.522	17.427	EPSD	ICGC;COSMIC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	Q12791	KCNMA1	P17252	PRKCA	S1200	S1204A	1204	Missense	distal	4	no	20.403	20.420	PhosphoSitePlus	ICGC	16.704	Up-regulation
AGC_PKC_PKCa_PRKCA_ST	P43119	PTGIR	P17252	PRKCA	S14	T9I	9	Missense	distal	-5	no	19.683	19.211	EPSD	ICGC;COSMIC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	P43119	PTGIR	P17252	PRKCA	S39	P43L	43	Missense	distal	4	no	20.602	20.010	EPSD	ICGC;COSMIC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	P43119	PTGIR	P17252	PRKCA	S39	R45H	45	Missense	distal	6	no	20.602	20.525	EPSD	ICGC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	P43119	PTGIR	P17252	PRKCA	S39	R41G	41	Missense	proximal	2	no	20.602	15.357	EPSD	ICGC;COSMIC	16.704	Loss
AGC_PKC_PKCa_PRKCA_ST	P43119	PTGIR	P17252	PRKCA	S328	G329R	329	Missense	proximal	1	no	21.703	22.657	PhosphoSitePlus	ICGC;COSMIC	16.704	Up-regulation
AGC_PKC_PKCa_PRKCA_ST	P43119	PTGIR	P17252	PRKCA	S328	A327T	327	Missense	proximal	-1	no	21.703	21.884	PhosphoSitePlus	ICGC;COSMIC	16.704	Up-regulation
AGC_PKC_PKCa_PRKCA_ST	P09211	GSTP1	P17252	PRKCA	S28	L21M	21	Missense	distal	-7	no	18.535	18.543	EPSD	ICGC;COSMIC	16.704	Up-regulation
AGC_PKC_PKCa_PRKCA_ST	P09211	GSTP1	P17252	PRKCA	S43	S43A	43	Missense	central	0	yes	17.670	0.000	EPSD	ICGC;COSMIC	16.704	Loss
AGC_PKC_PKCa_PRKCA_ST	P09211	GSTP1	P17252	PRKCA	S185	A179S	179	Missense	distal	-6	no	19.779	19.816	PhosphoSitePlus	ICGC;COSMIC	16.704	Up-regulation
AGC_PKC_PKCa_PRKCA_ST	P09211	GSTP1	P17252	PRKCA	S185	G182W	182	Missense	distal	-3	no	19.779	20.687	PhosphoSitePlus	ICGC;COSMIC	16.704	Up-regulation
AGC_PKC_PKCa_PRKCA_ST	Q01970	PLCB3	P17252	PRKCA	S26	G25W	25	Missense	proximal	-1	no	21.962	20.516	EPSD	ICGC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	Q01970	PLCB3	P17252	PRKCA	S26	T21N	21	Missense	distal	-5	no	21.962	21.705	EPSD	ICGC;COSMIC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	Q01970	PLCB3	P17252	PRKCA	S68	S67I	67	Missense	proximal	-1	no	18.185	16.902	EPSD	ICGC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	Q01970	PLCB3	P17252	PRKCA	S474	D479G	479	Missense	distal	5	no	17.287	17.368	EPSD	ICGC;COSMIC	16.704	Up-regulation
AGC_PKC_PKCa_PRKCA_ST	Q01970	PLCB3	P17252	PRKCA	S480	G482R	482	Missense	proximal	2	no	16.052	21.298	EPSD	ICGC;COSMIC	16.704	Gain
AGC_PKC_PKCa_PRKCA_ST	Q01970	PLCB3	P17252	PRKCA	S480	D479G	479	Missense	proximal	-1	no	16.052	16.796	EPSD	ICGC;COSMIC	16.704	Gain
AGC_PKC_PKCa_PRKCA_ST	Q01970	PLCB3	P17252	PRKCA	S916	S911R	911	Missense	distal	-5	no	17.963	18.390	EPSD	ICGC;COSMIC	16.704	Up-regulation
AGC_PKC_PKCa_PRKCA_ST	Q01970	PLCB3	P17252	PRKCA	S916	S916P	916	Missense	central	0	yes	17.963	0.000	EPSD	ICGC;COSMIC	16.704	Loss
AGC_PKC_PKCa_PRKCA_ST	Q01970	PLCB3	P17252	PRKCA	S916	P921T	921	Missense	distal	5	no	17.963	17.628	EPSD	ICGC;COSMIC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	Q01995	TAGLN	P17252	PRKCA	S7	G9V	9	Missense	proximal	2	no	18.512	18.744	EPSD	ICGC	16.704	Up-regulation
AGC_PKC_PKCa_PRKCA_ST	Q01995	TAGLN	P17252	PRKCA	S7	K4N	4	Missense	distal	-3	no	18.512	16.312	EPSD	ICGC;COSMIC;CCLE	16.704	Loss
AGC_PKC_PKCa_PRKCA_ST	Q01995	TAGLN	P17252	PRKCA	S181	M179I	179	Missense	proximal	-2	no	18.986	17.379	PhosphoSitePlus	ICGC;COSMIC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	O94759	TRPM2	P17252	PRKCA	S603	R610C	610	Missense	distal	7	no	16.880	16.657	EPSD	ICGC;COSMIC	16.704	Loss
AGC_PKC_PKCa_PRKCA_ST	O94759	TRPM2	P17252	PRKCA	S603	R610L	610	Missense	distal	7	no	16.880	16.836	EPSD	ICGC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	O94759	TRPM2	P17252	PRKCA	S603	N598K	598	Missense	distal	-5	no	16.880	17.223	EPSD	ICGC;COSMIC	16.704	Up-regulation
AGC_PKC_PKCa_PRKCA_ST	O94759	TRPM2	P17252	PRKCA	S612	R610C	610	Missense	proximal	-2	no	17.161	15.461	EPSD	ICGC;COSMIC	16.704	Loss
AGC_PKC_PKCa_PRKCA_ST	O94759	TRPM2	P17252	PRKCA	S612	R610L	610	Missense	proximal	-2	no	17.161	14.473	EPSD	ICGC	16.704	Loss
AGC_PKC_PKCa_PRKCA_ST	O94759	TRPM2	P17252	PRKCA	S612	S612A	612	Missense	central	0	yes	17.161	0.000	EPSD	ICGC;COSMIC	16.704	Loss
AGC_PKC_PKCa_PRKCA_ST	O94759	TRPM2	P17252	PRKCA	S772	K776R	776	Missense	distal	4	no	18.648	18.478	EPSD	ICGC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	O94759	TRPM2	P17252	PRKCA	S772	G769C	769	Missense	distal	-3	no	18.648	19.171	EPSD	ICGC;COSMIC	16.704	Up-regulation
AGC_PKC_PKCa_PRKCA_ST	O94759	TRPM2	P17252	PRKCA	S772	L767F	767	Missense	distal	-5	no	18.648	18.452	EPSD	ICGC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	O94759	TRPM2	P17252	PRKCA	S1172	P1166S	1166	Missense	distal	-6	no	16.832	16.864	EPSD	ICGC	16.704	Up-regulation
AGC_PKC_PKCa_PRKCA_ST	P13498	CYBA	P17252	PRKCA	T147	R141W	141	Missense	distal	-6	no	18.137	17.853	PhosphoSitePlus	ICGC;COSMIC;CCLE	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	P13498	CYBA	P17252	PRKCA	T147	P151L	151	Missense	distal	4	no	18.137	17.545	PhosphoSitePlus	ICGC;COSMIC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	P13498	CYBA	P17252	PRKCA	T147	P151S	151	Missense	distal	4	no	18.137	18.337	PhosphoSitePlus	ICGC;COSMIC	16.704	Up-regulation
AGC_PKC_PKCa_PRKCA_ST	O94901	SUN1	P17252	PRKCA	S48	R53H	53	Missense	distal	5	no	17.195	16.936	EPSD	ICGC;COSMIC;GDSC;CCLE	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	O94901	SUN1	P17252	PRKCA	S48	R54H	54	Missense	distal	6	no	17.195	17.118	EPSD	ICGC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	O94901	SUN1	P17252	PRKCA	S48	R50L	50	Missense	proximal	2	no	17.195	12.208	EPSD	ICGC;COSMIC	16.704	Loss
AGC_PKC_PKCa_PRKCA_ST	O94901	SUN1	P17252	PRKCA	S52	R53H	53	Missense	proximal	1	no	22.535	21.722	EPSD	ICGC;COSMIC;GDSC;CCLE	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	O94901	SUN1	P17252	PRKCA	S52	R57H	57	Missense	distal	5	no	22.535	22.275	EPSD	ICGC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	O94901	SUN1	P17252	PRKCA	S52	R54H	54	Missense	proximal	2	no	22.535	17.511	EPSD	ICGC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	O94901	SUN1	P17252	PRKCA	S52	R50L	50	Missense	proximal	-2	no	22.535	19.847	EPSD	ICGC;COSMIC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	O94901	SUN1	P17252	PRKCA	S55	R53H	53	Missense	proximal	-2	no	23.780	19.226	PhosphoSitePlus	ICGC;COSMIC;GDSC;CCLE	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	O94901	SUN1	P17252	PRKCA	S55	R57H	57	Missense	proximal	2	no	23.780	18.756	PhosphoSitePlus	ICGC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	O94901	SUN1	P17252	PRKCA	S55	A62S	62	Missense	distal	7	no	23.780	23.781	PhosphoSitePlus	ICGC	16.704	Up-regulation
AGC_PKC_PKCa_PRKCA_ST	O94901	SUN1	P17252	PRKCA	S55	R54H	54	Missense	proximal	-1	no	23.780	23.456	PhosphoSitePlus	ICGC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	O94901	SUN1	P17252	PRKCA	S55	R50L	50	Missense	distal	-5	no	23.780	23.652	PhosphoSitePlus	ICGC;COSMIC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	O94901	SUN1	P17252	PRKCA	S82	V81A	81	Missense	proximal	-1	no	16.743	17.647	EPSD	ICGC	16.704	Up-regulation
AGC_PKC_PKCa_PRKCA_ST	O94901	SUN1	P17252	PRKCA	S96	R94H	94	Missense	proximal	-2	no	18.711	14.158	EPSD	ICGC	16.704	Loss
AGC_PKC_PKCa_PRKCA_ST	O94901	SUN1	P17252	PRKCA	S96	K99R	99	Missense	distal	3	no	18.711	19.334	EPSD	ICGC;COSMIC	16.704	Up-regulation
AGC_PKC_PKCa_PRKCA_ST	O94901	SUN1	P17252	PRKCA	S96	R94C	94	Missense	proximal	-2	no	18.711	17.012	EPSD	ICGC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	O94901	SUN1	P17252	PRKCA	T97	R94H	94	Missense	distal	-3	no	23.472	19.616	EPSD	ICGC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	O94901	SUN1	P17252	PRKCA	T97	K99R	99	Missense	proximal	2	no	23.472	23.894	EPSD	ICGC;COSMIC	16.704	Up-regulation
AGC_PKC_PKCa_PRKCA_ST	O94901	SUN1	P17252	PRKCA	T97	R94C	94	Missense	distal	-3	no	23.472	20.733	EPSD	ICGC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	Q9C0K0	BCL11B	P17252	PRKCA	S2	R4C	4	Missense	proximal	2	no	24.765	20.415	PhosphoSitePlus	ICGC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	Q9C0K0	BCL11B	P17252	PRKCA	S13	Q14H	14	Missense	proximal	1	no	19.791	19.095	EPSD	ICGC;COSMIC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	Q9C0K0	BCL11B	P17252	PRKCA	S101	D94E	94	Missense	distal	-7	no	17.717	17.713	EPSD	ICGC;COSMIC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	Q9C0K0	BCL11B	P17252	PRKCA	S364	A360T	360	Missense	distal	-4	no	19.032	18.284	EPSD	ICGC;COSMIC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	Q9C0K0	BCL11B	P17252	PRKCA	S364	R368S	368	Missense	distal	4	no	19.032	18.786	EPSD	ICGC;COSMIC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	Q9C0K0	BCL11B	P17252	PRKCA	S483	D489N	489	Missense	distal	6	no	18.915	18.830	EPSD	ICGC;COSMIC;GDSC;CCLE	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	Q9C0K0	BCL11B	P17252	PRKCA	S765	S765L	765	Missense	central	0	yes	17.505	0.000	EPSD	ICGC;COSMIC	16.704	Loss
AGC_PKC_PKCa_PRKCA_ST	Q9C0K0	BCL11B	P17252	PRKCA	S765	G769S	769	Missense	distal	4	no	17.505	17.863	EPSD	ICGC	16.704	Up-regulation
AGC_PKC_PKCa_PRKCA_ST	Q9C0K0	BCL11B	P17252	PRKCA	S788	S789F	789	Missense	proximal	1	no	21.436	22.919	EPSD	ICGC;CCLE	16.704	Up-regulation
AGC_PKC_PKCa_PRKCA_ST	Q9C0K0	BCL11B	P17252	PRKCA	S789	S789F	789	Missense	central	0	yes	19.514	0.000	EPSD	ICGC;CCLE	16.704	Loss
AGC_PKC_PKCa_PRKCA_ST	Q9C0K0	BCL11B	P17252	PRKCA	S817	E821K	821	Missense	distal	4	no	21.134	21.673	EPSD	ICGC	16.704	Up-regulation
AGC_PKC_PKCa_PRKCA_ST	Q9C0K0	BCL11B	P17252	PRKCA	T819	E821K	821	Missense	proximal	2	no	14.544	19.823	EPSD	ICGC	16.704	Gain
AGC_PKC_PKCa_PRKCA_ST	P50552	VASP	P17252	PRKCA	S8	S9I	9	Missense	proximal	1	no	16.173	17.835	EPSD	ICGC	16.704	Gain
AGC_PKC_PKCa_PRKCA_ST	P50552	VASP	P17252	PRKCA	S157	A164S	164	Missense	distal	7	no	18.806	18.808	PhosphoSitePlus	ICGC	16.704	Up-regulation
AGC_PKC_PKCa_PRKCA_ST	P50552	VASP	P17252	PRKCA	S157	V156F	156	Missense	proximal	-1	no	18.806	19.561	PhosphoSitePlus	ICGC	16.704	Up-regulation
AGC_PKC_PKCa_PRKCA_ST	P50552	VASP	P17252	PRKCA	S157	I152M	152	Missense	distal	-5	no	18.806	19.211	PhosphoSitePlus	ICGC;COSMIC	16.704	Up-regulation
AGC_PKC_PKCa_PRKCA_ST	P50552	VASP	P17252	PRKCA	S157	S157Y	157	Missense	central	0	yes	18.806	0.000	PhosphoSitePlus	ICGC;COSMIC	16.704	Loss
AGC_PKC_PKCa_PRKCA_ST	P50552	VASP	P17252	PRKCA	S255	A250T	250	Missense	distal	-5	no	19.553	19.934	EPSD	ICGC	16.704	Up-regulation
AGC_PKC_PKCa_PRKCA_ST	P50552	VASP	P17252	PRKCA	S255	A253G	253	Missense	proximal	-2	no	19.553	19.766	EPSD	ICGC;COSMIC	16.704	Up-regulation
AGC_PKC_PKCa_PRKCA_ST	P50552	VASP	P17252	PRKCA	S255	G256C	256	Missense	proximal	1	no	19.553	17.670	EPSD	ICGC;COSMIC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	P50552	VASP	P17252	PRKCA	S255	G262V	262	Missense	distal	7	no	19.553	19.475	EPSD	ICGC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	P50552	VASP	P17252	PRKCA	T278	P285H	285	Missense	distal	7	no	17.590	17.529	EPSD	ICGC;COSMIC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	P50552	VASP	P17252	PRKCA	T278	G281V	281	Missense	distal	3	no	17.590	16.376	EPSD	ICGC;COSMIC	16.704	Loss
AGC_PKC_PKCa_PRKCA_ST	P50552	VASP	P17252	PRKCA	S305	P300Q	300	Missense	distal	-5	no	20.182	20.131	EPSD	ICGC;COSMIC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	P30411	BDKRB2	P17252	PRKCA	S12	W5C	5	Missense	distal	-7	no	20.839	20.836	EPSD	ICGC;COSMIC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	P30411	BDKRB2	P17252	PRKCA	S12	S8T	8	Missense	distal	-4	no	20.839	20.177	EPSD	ICGC;COSMIC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	P30411	BDKRB2	P17252	PRKCA	S12	R14C	14	Missense	proximal	2	no	20.839	16.488	EPSD	ICGC;COSMIC	16.704	Loss
AGC_PKC_PKCa_PRKCA_ST	P30411	BDKRB2	P17252	PRKCA	S12	S12Y	12	Missense	central	0	yes	20.839	0.000	EPSD	ICGC;COSMIC	16.704	Loss
AGC_PKC_PKCa_PRKCA_ST	Q01954	BNC1	P17252	PRKCA	S7	R3Q	3	Missense	distal	-4	no	21.167	20.790	EPSD	ICGC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	Q01954	BNC1	P17252	PRKCA	S398	V395M	395	Missense	distal	-3	no	17.878	18.596	EPSD	ICGC	16.704	Up-regulation
AGC_PKC_PKCa_PRKCA_ST	Q01954	BNC1	P17252	PRKCA	S398	R404H	404	Missense	distal	6	no	17.878	17.801	EPSD	ICGC;COSMIC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	Q01954	BNC1	P17252	PRKCA	S398	G391E	391	Missense	distal	-7	no	17.878	17.875	EPSD	ICGC;COSMIC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	Q01954	BNC1	P17252	PRKCA	S537	S537Y	537	Missense	central	0	yes	22.040	0.000	EPSD	ICGC;COSMIC	16.704	Loss
AGC_PKC_PKCa_PRKCA_ST	Q01954	BNC1	P17252	PRKCA	S541	S537Y	537	Missense	distal	-4	no	17.890	17.696	PhosphoSitePlus	ICGC;COSMIC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	Q01954	BNC1	P17252	PRKCA	S938	G941R	941	Missense	distal	3	no	17.817	18.456	EPSD	ICGC;COSMIC	16.704	Up-regulation
AGC_PKC_PKCa_PRKCA_ST	Q01954	BNC1	P17252	PRKCA	S938	A945D	945	Missense	distal	7	no	17.817	17.821	EPSD	ICGC	16.704	Up-regulation
AGC_PKC_PKCa_PRKCA_ST	Q01954	BNC1	P17252	PRKCA	T942	G941R	941	Missense	proximal	-1	no	17.837	17.976	EPSD	ICGC;COSMIC	16.704	Up-regulation
AGC_PKC_PKCa_PRKCA_ST	Q01954	BNC1	P17252	PRKCA	T942	A945D	945	Missense	distal	3	no	17.837	17.710	EPSD	ICGC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	Q14524	SCN5A	P17252	PRKCA	S11	T10N	10	Missense	proximal	-1	no	20.342	20.562	EPSD	ICGC;COSMIC	16.704	Up-regulation
AGC_PKC_PKCa_PRKCA_ST	Q14524	SCN5A	P17252	PRKCA	S11	G9V	9	Missense	proximal	-2	no	20.342	20.372	EPSD	ICGC;COSMIC	16.704	Up-regulation
AGC_PKC_PKCa_PRKCA_ST	Q14524	SCN5A	P17252	PRKCA	S11	R18W	18	Missense	distal	7	no	20.342	20.161	EPSD	ICGC;COSMIC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	Q14524	SCN5A	P17252	PRKCA	S12	T10N	10	Missense	proximal	-2	no	24.060	23.758	EPSD	ICGC;COSMIC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	Q14524	SCN5A	P17252	PRKCA	S12	G9V	9	Missense	distal	-3	no	24.060	23.632	EPSD	ICGC;COSMIC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	Q14524	SCN5A	P17252	PRKCA	S12	R18W	18	Missense	distal	6	no	24.060	23.812	EPSD	ICGC;COSMIC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	Q14524	SCN5A	P17252	PRKCA	T17	T10N	10	Missense	distal	-7	no	18.215	18.213	EPSD	ICGC;COSMIC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	Q14524	SCN5A	P17252	PRKCA	T17	R18W	18	Missense	proximal	1	no	18.215	17.491	EPSD	ICGC;COSMIC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	Q14524	SCN5A	P17252	PRKCA	S20	E25K	25	Missense	distal	5	no	16.725	17.139	EPSD	ICGC;COSMIC	16.704	Up-regulation
AGC_PKC_PKCa_PRKCA_ST	Q14524	SCN5A	P17252	PRKCA	S20	R18W	18	Missense	proximal	-2	no	16.725	14.728	EPSD	ICGC;COSMIC	16.704	Loss
AGC_PKC_PKCa_PRKCA_ST	Q14524	SCN5A	P17252	PRKCA	S476	S471I	471	Missense	distal	-5	no	23.937	23.792	EPSD	ICGC;COSMIC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	Q14524	SCN5A	P17252	PRKCA	S476	R481W	481	Missense	distal	5	no	23.937	23.429	EPSD	ICGC;COSMIC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	Q14524	SCN5A	P17252	PRKCA	S476	R481L	481	Missense	distal	5	no	23.937	23.605	EPSD	ICGC;COSMIC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	Q14524	SCN5A	P17252	PRKCA	S483	G490E	490	Missense	distal	7	no	18.998	18.927	EPSD	ICGC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	Q14524	SCN5A	P17252	PRKCA	S483	R481W	481	Missense	proximal	-2	no	18.998	17.001	EPSD	ICGC;COSMIC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	Q14524	SCN5A	P17252	PRKCA	S483	S484P	484	Missense	proximal	1	no	18.998	19.397	EPSD	ICGC	16.704	Up-regulation
AGC_PKC_PKCa_PRKCA_ST	Q14524	SCN5A	P17252	PRKCA	S483	R481L	481	Missense	proximal	-2	no	18.998	16.310	EPSD	ICGC;COSMIC	16.704	Loss
AGC_PKC_PKCa_PRKCA_ST	Q14524	SCN5A	P17252	PRKCA	S483	G490V	490	Missense	distal	7	no	18.998	18.920	EPSD	ICGC;COSMIC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	Q14524	SCN5A	P17252	PRKCA	S484	G490E	490	Missense	distal	6	no	17.923	17.966	EPSD	ICGC	16.704	Up-regulation
AGC_PKC_PKCa_PRKCA_ST	Q14524	SCN5A	P17252	PRKCA	S484	R481W	481	Missense	distal	-3	no	17.923	15.569	EPSD	ICGC;COSMIC	16.704	Loss
AGC_PKC_PKCa_PRKCA_ST	Q14524	SCN5A	P17252	PRKCA	S484	S484P	484	Missense	central	0	yes	17.923	0.000	EPSD	ICGC	16.704	Loss
AGC_PKC_PKCa_PRKCA_ST	Q14524	SCN5A	P17252	PRKCA	S484	R481L	481	Missense	distal	-3	no	17.923	13.567	EPSD	ICGC;COSMIC	16.704	Loss
AGC_PKC_PKCa_PRKCA_ST	Q14524	SCN5A	P17252	PRKCA	S484	G490V	490	Missense	distal	6	no	17.923	17.912	EPSD	ICGC;COSMIC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	Q14524	SCN5A	P17252	PRKCA	S499	K496R	496	Missense	distal	-3	no	15.630	17.656	EPSD	ICGC	16.704	Gain
AGC_PKC_PKCa_PRKCA_ST	Q14524	SCN5A	P17252	PRKCA	S519	R526H	526	Missense	distal	7	no	21.739	21.667	EPSD	ICGC;COSMIC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	Q14524	SCN5A	P17252	PRKCA	S524	R526H	526	Missense	proximal	2	no	21.073	16.049	EPSD	ICGC;COSMIC	16.704	Loss
AGC_PKC_PKCa_PRKCA_ST	Q14524	SCN5A	P17252	PRKCA	S524	G527R	527	Missense	distal	3	no	21.073	21.713	EPSD	ICGC;COSMIC	16.704	Up-regulation
AGC_PKC_PKCa_PRKCA_ST	Q14524	SCN5A	P17252	PRKCA	S525	R526H	526	Missense	proximal	1	no	17.417	16.604	EPSD	ICGC;COSMIC	16.704	Loss
AGC_PKC_PKCa_PRKCA_ST	Q14524	SCN5A	P17252	PRKCA	S525	G527R	527	Missense	proximal	2	no	17.417	22.663	EPSD	ICGC;COSMIC	16.704	Up-regulation
AGC_PKC_PKCa_PRKCA_ST	Q14524	SCN5A	P17252	PRKCA	S528	R533H	533	Missense	distal	5	no	19.052	18.793	EPSD	ICGC;COSMIC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	Q14524	SCN5A	P17252	PRKCA	S528	R526H	526	Missense	proximal	-2	no	19.052	14.499	EPSD	ICGC;COSMIC	16.704	Loss
AGC_PKC_PKCa_PRKCA_ST	Q14524	SCN5A	P17252	PRKCA	S528	G527R	527	Missense	proximal	-1	no	19.052	19.192	EPSD	ICGC;COSMIC	16.704	Up-regulation
AGC_PKC_PKCa_PRKCA_ST	Q14524	SCN5A	P17252	PRKCA	T531	D536Y	536	Missense	distal	5	no	20.137	20.384	EPSD	ICGC;COSMIC	16.704	Up-regulation
AGC_PKC_PKCa_PRKCA_ST	Q14524	SCN5A	P17252	PRKCA	T531	R533H	533	Missense	proximal	2	no	20.137	15.113	EPSD	ICGC;COSMIC	16.704	Loss
AGC_PKC_PKCa_PRKCA_ST	Q14524	SCN5A	P17252	PRKCA	T531	R526H	526	Missense	distal	-5	no	20.137	19.781	EPSD	ICGC;COSMIC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	Q14524	SCN5A	P17252	PRKCA	T531	G527R	527	Missense	distal	-4	no	20.137	20.238	EPSD	ICGC;COSMIC	16.704	Up-regulation
AGC_PKC_PKCa_PRKCA_ST	Q14524	SCN5A	P17252	PRKCA	S581	A582V	582	Missense	proximal	1	no	16.895	17.049	EPSD	ICGC;COSMIC	16.704	Up-regulation
AGC_PKC_PKCa_PRKCA_ST	Q14524	SCN5A	P17252	PRKCA	S581	H585N	585	Missense	distal	4	no	16.895	16.221	EPSD	ICGC	16.704	Loss
AGC_PKC_PKCa_PRKCA_ST	Q14524	SCN5A	P17252	PRKCA	S581	A586D	586	Missense	distal	5	no	16.895	16.572	EPSD	ICGC;COSMIC	16.704	Loss
AGC_PKC_PKCa_PRKCA_ST	Q14524	SCN5A	P17252	PRKCA	S1079	S1074R	1074	Missense	distal	-5	no	16.643	17.070	EPSD	ICGC;COSMIC	16.704	Gain
AGC_PKC_PKCa_PRKCA_ST	P35900	KRT20	P17252	PRKCA	S11	H9N	9	Missense	proximal	-2	no	18.157	19.515	EPSD	ICGC;COSMIC	16.704	Up-regulation
AGC_PKC_PKCa_PRKCA_ST	P35900	KRT20	P17252	PRKCA	S11	S11R	11	Missense	central	0	yes	18.157	0.000	EPSD	ICGC;COSMIC	16.704	Loss
AGC_PKC_PKCa_PRKCA_ST	P35900	KRT20	P17252	PRKCA	S13	H9N	9	Missense	distal	-4	no	18.842	18.893	PhosphoSitePlus	ICGC;COSMIC	16.704	Up-regulation
AGC_PKC_PKCa_PRKCA_ST	P35900	KRT20	P17252	PRKCA	S13	S11R	11	Missense	proximal	-2	no	18.842	22.143	PhosphoSitePlus	ICGC;COSMIC	16.704	Up-regulation
AGC_PKC_PKCa_PRKCA_ST	P35900	KRT20	P17252	PRKCA	S14	H9N	9	Missense	distal	-5	no	16.717	16.716	EPSD	ICGC;COSMIC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	P35900	KRT20	P17252	PRKCA	S14	S11R	11	Missense	distal	-3	no	16.717	19.586	EPSD	ICGC;COSMIC	16.704	Up-regulation
AGC_PKC_PKCa_PRKCA_ST	P35900	KRT20	P17252	PRKCA	S83	A82V	82	Missense	proximal	-1	no	18.907	18.003	EPSD	ICGC;COSMIC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	P35900	KRT20	P17252	PRKCA	S83	R80C	80	Missense	distal	-3	no	18.907	16.168	EPSD	ICGC;COSMIC	16.704	Loss
AGC_PKC_PKCa_PRKCA_ST	P35900	KRT20	P17252	PRKCA	S83	R80H	80	Missense	distal	-3	no	18.907	15.051	EPSD	ICGC;COSMIC	16.704	Loss
AGC_PKC_PKCa_PRKCA_ST	P35900	KRT20	P17252	PRKCA	S96	L98R	98	Missense	proximal	2	no	12.578	17.565	EPSD	ICGC	16.704	Gain
AGC_PKC_PKCa_PRKCA_ST	P35900	KRT20	P17252	PRKCA	S118	A113D	113	Missense	distal	-5	no	16.820	16.915	EPSD	ICGC;COSMIC	16.704	Up-regulation
AGC_PKC_PKCa_PRKCA_ST	P35900	KRT20	P17252	PRKCA	S118	G114D	114	Missense	distal	-4	no	16.820	16.050	EPSD	ICGC;COSMIC	16.704	Loss
AGC_PKC_PKCa_PRKCA_ST	P35900	KRT20	P17252	PRKCA	S293	T292A	292	Missense	proximal	-1	no	18.661	18.480	EPSD	ICGC;COSMIC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	P35900	KRT20	P17252	PRKCA	T369	E366K	366	Missense	distal	-3	no	15.265	18.177	EPSD	ICGC	16.704	Gain
AGC_PKC_PKCa_PRKCA_ST	P35900	KRT20	P17252	PRKCA	T388	E390K	390	Missense	proximal	2	no	11.964	17.243	EPSD	ICGC	16.704	Gain
AGC_PKC_PKCa_PRKCA_ST	Q71U36	TUBA1A	P17252	PRKCA	T82	Y83N	83	Missense	proximal	1	no	19.353	18.589	EPSD	ICGC;COSMIC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	Q71U36	TUBA1A	P17252	PRKCA	S158	M154T	154	Missense	distal	-4	no	16.944	16.010	EPSD	ICGC;COSMIC	16.704	Loss
AGC_PKC_PKCa_PRKCA_ST	Q01844	EWSR1	P17252	PRKCA	S259	S255G	255	Missense	distal	-4	no	17.340	17.432	EPSD	ICGC;COSMIC	16.704	Up-regulation
AGC_PKC_PKCa_PRKCA_ST	Q15762	CD226	P17252	PRKCA	S329	R331S	331	Missense	proximal	2	no	16.809	12.189	PhosphoSitePlus	ICGC;COSMIC	16.704	Loss
AGC_PKC_PKCa_PRKCA_ST	P49840	GSK3A	P17252	PRKCA	S97	D96E	96	Missense	proximal	-1	no	19.659	20.172	EPSD	ICGC;COSMIC	16.704	Up-regulation
AGC_PKC_PKCa_PRKCA_ST	P49840	GSK3A	P17252	PRKCA	S97	R95G	95	Missense	proximal	-2	no	19.659	16.787	EPSD	ICGC;COSMIC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	P49840	GSK3A	P17252	PRKCA	S97	G98R	98	Missense	proximal	1	no	19.659	20.612	EPSD	ICGC	16.704	Up-regulation
AGC_PKC_PKCa_PRKCA_ST	P49840	GSK3A	P17252	PRKCA	S97	V103A	103	Missense	distal	6	no	19.659	19.777	EPSD	ICGC;COSMIC	16.704	Up-regulation
AGC_PKC_PKCa_PRKCA_ST	P14416	DRD2	P17252	PRKCA	S147	R150C	150	Missense	distal	3	no	22.313	19.694	EPSD	ICGC;COSMIC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	P14416	DRD2	P17252	PRKCA	S147	R145C	145	Missense	proximal	-2	no	22.313	20.613	EPSD	ICGC;COSMIC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	P14416	DRD2	P17252	PRKCA	S147	S147N	147	Missense	central	0	yes	22.313	0.000	EPSD	ICGC	16.704	Loss
AGC_PKC_PKCa_PRKCA_ST	P14416	DRD2	P17252	PRKCA	S148	R150C	150	Missense	proximal	2	no	22.832	18.482	EPSD	ICGC;COSMIC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	P14416	DRD2	P17252	PRKCA	S148	R145C	145	Missense	distal	-3	no	22.832	20.093	EPSD	ICGC;COSMIC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	P14416	DRD2	P17252	PRKCA	S148	S147N	147	Missense	proximal	-1	no	22.832	22.675	EPSD	ICGC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	P14416	DRD2	P17252	PRKCA	T225	S228R	228	Missense	distal	3	no	21.887	23.278	EPSD	ICGC	16.704	Up-regulation
AGC_PKC_PKCa_PRKCA_ST	P14416	DRD2	P17252	PRKCA	T225	R227S	227	Missense	proximal	2	no	21.887	17.267	EPSD	ICGC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	P14416	DRD2	P17252	PRKCA	T225	R227C	227	Missense	proximal	2	no	21.887	17.536	EPSD	ICGC;COSMIC;GDSC;CCLE	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	P14416	DRD2	P17252	PRKCA	T225	R218K	218	Missense	distal	-7	no	21.887	21.882	EPSD	ICGC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	P14416	DRD2	P17252	PRKCA	T225	R230Q	230	Missense	distal	5	no	21.887	21.878	EPSD	ICGC;COSMIC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	P14416	DRD2	P17252	PRKCA	S228	S228R	228	Missense	central	0	yes	18.941	0.000	EPSD;PhosphoSitePlus	ICGC	16.704	Loss
AGC_PKC_PKCa_PRKCA_ST	P14416	DRD2	P17252	PRKCA	S228	R227S	227	Missense	proximal	-1	no	18.941	18.553	EPSD;PhosphoSitePlus	ICGC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	P14416	DRD2	P17252	PRKCA	S228	R227C	227	Missense	proximal	-1	no	18.941	16.281	EPSD;PhosphoSitePlus	ICGC;COSMIC;GDSC;CCLE	16.704	Loss
AGC_PKC_PKCa_PRKCA_ST	P14416	DRD2	P17252	PRKCA	S228	R230Q	230	Missense	proximal	2	no	18.941	15.106	EPSD;PhosphoSitePlus	ICGC;COSMIC	16.704	Loss
AGC_PKC_PKCa_PRKCA_ST	P14416	DRD2	P17252	PRKCA	S229	S228R	228	Missense	proximal	-1	no	17.910	18.297	PhosphoSitePlus;EPSD	ICGC	16.704	Up-regulation
AGC_PKC_PKCa_PRKCA_ST	P14416	DRD2	P17252	PRKCA	S229	R227S	227	Missense	proximal	-2	no	17.910	14.608	PhosphoSitePlus;EPSD	ICGC	16.704	Loss
AGC_PKC_PKCa_PRKCA_ST	P14416	DRD2	P17252	PRKCA	S229	R227C	227	Missense	proximal	-2	no	17.910	16.210	PhosphoSitePlus;EPSD	ICGC;COSMIC;GDSC;CCLE	16.704	Loss
AGC_PKC_PKCa_PRKCA_ST	P14416	DRD2	P17252	PRKCA	S229	R230Q	230	Missense	proximal	1	no	17.910	17.793	PhosphoSitePlus;EPSD	ICGC;COSMIC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	P14416	DRD2	P17252	PRKCA	S354	P347H	347	Missense	distal	-7	no	21.245	21.246	EPSD	ICGC	16.704	Up-regulation
AGC_PKC_PKCa_PRKCA_ST	P14416	DRD2	P17252	PRKCA	S354	N348D	348	Missense	distal	-6	no	21.245	21.218	EPSD	ICGC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	P49685	GPR15	P17252	PRKCA	S357	R356S	356	Missense	proximal	-1	no	17.197	16.810	PhosphoSitePlus	ICGC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	P49685	GPR15	P17252	PRKCA	S357	F350Y	350	Missense	distal	-7	no	17.197	17.205	PhosphoSitePlus	ICGC;COSMIC	16.704	Up-regulation
AGC_PKC_PKCa_PRKCA_ST	Q96QS3	ARX	P17252	PRKCA	S37	S31N	31	Missense	distal	-6	no	17.590	17.533	EPSD	ICGC;COSMIC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	Q96QS3	ARX	P17252	PRKCA	S37	D30Y	30	Missense	distal	-7	no	17.590	17.595	EPSD	ICGC;COSMIC	16.704	Up-regulation
AGC_PKC_PKCa_PRKCA_ST	Q96QS3	ARX	P17252	PRKCA	S67	Q65K	65	Missense	proximal	-2	no	20.150	20.282	EPSD	ICGC	16.704	Up-regulation
AGC_PKC_PKCa_PRKCA_ST	Q96QS3	ARX	P17252	PRKCA	S67	K62N	62	Missense	distal	-5	no	20.150	19.807	EPSD	ICGC;COSMIC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	Q96QS3	ARX	P17252	PRKCA	S174	R176S	176	Missense	proximal	2	no	23.461	18.842	PhosphoSitePlus	ICGC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	P08581	MET	P17252	PRKCA	S985	R987G	987	Missense	proximal	2	no	18.504	13.259	PhosphoSitePlus	ICGC;COSMIC	16.704	Loss
AGC_PKC_PKCa_PRKCA_ST	P08581	MET	P17252	PRKCA	S985	L983H	983	Missense	proximal	-2	no	18.504	16.638	PhosphoSitePlus	ICGC;COSMIC	16.704	Loss
AGC_PKC_PKCa_PRKCA_ST	P08581	MET	P17252	PRKCA	S985	H979Y	979	Missense	distal	-6	no	18.504	18.445	PhosphoSitePlus	ICGC;COSMIC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	P08581	MET	P17252	PRKCA	S985	R982M	982	Missense	distal	-3	no	18.504	15.532	PhosphoSitePlus	ICGC;COSMIC	16.704	Loss
AGC_PKC_PKCa_PRKCA_ST	P22460	KCNA5	P17252	PRKCA	T15	D20N	20	Missense	distal	5	no	21.251	21.250	PhosphoSitePlus	ICGC;COSMIC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	P22460	KCNA5	P17252	PRKCA	T15	N10S	10	Missense	distal	-5	no	21.251	21.180	PhosphoSitePlus	ICGC;COSMIC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	P22460	KCNA5	P17252	PRKCA	T15	T15I	15	Missense	central	0	yes	21.251	0.000	PhosphoSitePlus	ICGC;COSMIC	16.704	Loss
AGC_PKC_PKCa_PRKCA_ST	P22460	KCNA5	P17252	PRKCA	S414	G419W	419	Missense	distal	5	no	17.936	17.709	EPSD	ICGC;COSMIC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	P22460	KCNA5	P17252	PRKCA	S414	S417F	417	Missense	distal	3	no	17.936	17.423	EPSD	ICGC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	P22460	KCNA5	P17252	PRKCA	S414	S414Y	414	Missense	central	0	yes	17.936	0.000	EPSD	ICGC;COSMIC	16.704	Loss
AGC_PKC_PKCa_PRKCA_ST	P22460	KCNA5	P17252	PRKCA	S414	G419E	419	Missense	distal	5	no	17.936	17.947	EPSD	ICGC	16.704	Up-regulation
AGC_PKC_PKCa_PRKCA_ST	P22460	KCNA5	P17252	PRKCA	S417	G419W	419	Missense	proximal	2	no	17.099	16.904	EPSD	ICGC;COSMIC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	P22460	KCNA5	P17252	PRKCA	S417	S417F	417	Missense	central	0	yes	17.099	0.000	EPSD	ICGC	16.704	Loss
AGC_PKC_PKCa_PRKCA_ST	P22460	KCNA5	P17252	PRKCA	S417	S414Y	414	Missense	distal	-3	no	17.099	15.409	EPSD	ICGC;COSMIC	16.704	Loss
AGC_PKC_PKCa_PRKCA_ST	P22460	KCNA5	P17252	PRKCA	S417	G419E	419	Missense	proximal	2	no	17.099	16.643	EPSD	ICGC	16.704	Loss
AGC_PKC_PKCa_PRKCA_ST	P22460	KCNA5	P17252	PRKCA	S430	T426I	426	Missense	distal	-4	no	17.446	17.666	EPSD	ICGC	16.704	Up-regulation
AGC_PKC_PKCa_PRKCA_ST	P22460	KCNA5	P17252	PRKCA	S430	S430P	430	Missense	central	0	yes	17.446	0.000	EPSD	ICGC	16.704	Loss
AGC_PKC_PKCa_PRKCA_ST	P22460	KCNA5	P17252	PRKCA	S430	L434P	434	Missense	distal	4	no	17.446	18.039	EPSD	ICGC;COSMIC	16.704	Up-regulation
AGC_PKC_PKCa_PRKCA_ST	P22460	KCNA5	P17252	PRKCA	S430	S430F	430	Missense	central	0	yes	17.446	0.000	EPSD	ICGC;COSMIC	16.704	Loss
AGC_PKC_PKCa_PRKCA_ST	P22460	KCNA5	P17252	PRKCA	S557	G558E	558	Missense	proximal	1	no	17.842	17.229	EPSD	ICGC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	P22460	KCNA5	P17252	PRKCA	S575	G568W	568	Missense	distal	-7	no	18.442	18.434	EPSD	ICGC;COSMIC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	P22460	KCNA5	P17252	PRKCA	S575	A573S	573	Missense	proximal	-2	no	18.442	18.225	EPSD	ICGC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	P22460	KCNA5	P17252	PRKCA	S575	G568V	568	Missense	distal	-7	no	18.442	18.438	EPSD	ICGC;COSMIC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	P22460	KCNA5	P17252	PRKCA	S575	C581F	581	Missense	distal	6	no	18.442	18.568	EPSD	ICGC	16.704	Up-regulation
AGC_PKC_PKCa_PRKCA_ST	P22460	KCNA5	P17252	PRKCA	S575	A573T	573	Missense	proximal	-2	no	18.442	18.634	EPSD	ICGC	16.704	Up-regulation
AGC_PKC_PKCa_PRKCA_ST	Q92837	FRAT1	P17252	PRKCA	S179	S179P	179	Missense	central	0	yes	16.801	0.000	EPSD	ICGC;COSMIC	16.704	Loss
AGC_PKC_PKCa_PRKCA_ST	Q92837	FRAT1	P17252	PRKCA	S188	Q189L	189	Missense	proximal	1	no	22.212	21.982	PhosphoSitePlus	ICGC;COSMIC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	Q92837	FRAT1	P17252	PRKCA	S188	T194A	194	Missense	distal	6	no	22.212	22.290	PhosphoSitePlus	ICGC;COSMIC	16.704	Up-regulation
AGC_PKC_PKCa_PRKCA_ST	Q92837	FRAT1	P17252	PRKCA	S241	G238R	238	Missense	distal	-3	no	13.500	16.762	EPSD	ICGC;COSMIC	16.704	Gain
TK_Src_SRM_Y	Q13882	PTK6	Q9H3Y6	SRMS	Y447	L441I	441	Missense	distal	-6	no	3.022	3.058	PhosphoSitePlus	ICGC	1.179	Up-regulation
TK_Src_SRM_Y	Q13882	PTK6	Q9H3Y6	SRMS	Y447	F444V	444	Missense	distal	-3	no	3.022	3.103	PhosphoSitePlus	ICGC	1.179	Up-regulation
CAMK_CAMKL_BRSK_BRSK1_ST	P23258	TUBG1	Q8TDC3	BRSK1	S131	C138F	138	Missense	distal	7	no	1.301	1.291	PhosphoSitePlus;EPSD	ICGC	0.579	Down-regulation
CAMK_CAMKL_BRSK_BRSK1_ST	P23258	TUBG1	Q8TDC3	BRSK1	S131	R124Q	124	Missense	distal	-7	no	1.301	1.306	PhosphoSitePlus;EPSD	ICGC;COSMIC	0.579	Up-regulation
CAMK_CAMKL_BRSK_BRSK1_ST	P23258	TUBG1	Q8TDC3	BRSK1	S131	R124L	124	Missense	distal	-7	no	1.301	1.310	PhosphoSitePlus;EPSD	ICGC;COSMIC	0.579	Up-regulation
CAMK_CAMKL_BRSK_BRSK1_ST	P23258	TUBG1	Q8TDC3	BRSK1	S306	R311L	311	Missense	distal	5	no	0.575	0.632	EPSD	ICGC	0.579	Gain
CAMK_CAMKL_BRSK_BRSK1_ST	P23258	TUBG1	Q8TDC3	BRSK1	S385	S386L	386	Missense	proximal	1	no	1.207	1.160	EPSD;PhosphoSitePlus	ICGC;COSMIC	0.579	Down-regulation
CAMK_CAMKL_BRSK_BRSK1_ST	P23258	TUBG1	Q8TDC3	BRSK1	S385	A379D	379	Missense	distal	-6	no	1.207	1.256	EPSD;PhosphoSitePlus	ICGC	0.579	Up-regulation
Other_IKK_IKBKB_ST	Q9NQC7	CYLD	O14920	IKBKB	S62	V55M	55	Missense	distal	-7	no	19.531	22.929	EPSD	ICGC;COSMIC;GDSC;CCLE	16.613	Up-regulation
Other_IKK_IKBKB_ST	Q9NQC7	CYLD	O14920	IKBKB	S362	D364N	364	Missense	proximal	2	no	17.645	17.716	EPSD	ICGC;COSMIC	16.613	Up-regulation
Other_IKK_IKBKB_ST	Q9NQC7	CYLD	O14920	IKBKB	S432	G434D	434	Missense	proximal	2	no	20.183	20.716	PhosphoSitePlus;EPSD	ICGC	16.613	Up-regulation
Other_IKK_IKBKB_ST	Q9NQC7	CYLD	O14920	IKBKB	S436	G434D	434	Missense	proximal	-2	no	22.593	21.478	EPSD;PhosphoSitePlus	ICGC	16.613	Down-regulation
Other_IKK_IKBKB_ST	Q9NQC7	CYLD	O14920	IKBKB	S439	G434D	434	Missense	distal	-5	no	20.831	20.916	EPSD;PhosphoSitePlus	ICGC	16.613	Up-regulation
Other_IKK_IKBKB_ST	Q9NQC7	CYLD	O14920	IKBKB	S441	G434D	434	Missense	distal	-7	no	20.238	20.368	EPSD;PhosphoSitePlus	ICGC	16.613	Up-regulation
Other_IKK_IKBKB_ST	Q99704	DOK1	O14920	IKBKB	S56	L60M	60	Missense	distal	4	no	13.637	17.812	EPSD	ICGC	16.613	Gain
Other_IKK_IKBKB_ST	Q99704	DOK1	O14920	IKBKB	S281	P280S	280	Missense	proximal	-1	no	17.935	17.932	EPSD	ICGC;COSMIC	16.613	Down-regulation
Other_IKK_IKBKB_ST	Q99704	DOK1	O14920	IKBKB	S302	A297T	297	Missense	distal	-5	no	20.031	20.098	EPSD	ICGC;COSMIC	16.613	Up-regulation
Other_IKK_IKBKB_ST	Q99704	DOK1	O14920	IKBKB	S313	D312G	312	Missense	proximal	-1	no	18.244	18.332	EPSD	ICGC	16.613	Up-regulation
Other_IKK_IKBKB_ST	Q99704	DOK1	O14920	IKBKB	S321	S321I	321	Missense	central	0	yes	17.906	0.000	EPSD	ICGC;COSMIC	16.613	Loss
Other_IKK_IKBKB_ST	Q99704	DOK1	O14920	IKBKB	S443	L448M	448	Missense	distal	5	no	27.181	30.084	EPSD;PhosphoSitePlus	ICGC;COSMIC	16.613	Up-regulation
Other_IKK_IKBKB_ST	Q99704	DOK1	O14920	IKBKB	S446	L448M	448	Missense	proximal	2	no	19.754	20.827	PhosphoSitePlus;EPSD	ICGC;COSMIC	16.613	Up-regulation
Other_IKK_IKBKB_ST	Q99704	DOK1	O14920	IKBKB	S450	L448M	448	Missense	proximal	-2	no	21.826	20.902	EPSD;PhosphoSitePlus	ICGC;COSMIC	16.613	Down-regulation
Other_IKK_IKBKB_ST	Q99704	DOK1	O14920	IKBKB	S455	L448M	448	Missense	distal	-7	no	25.294	27.656	EPSD	ICGC;COSMIC	16.613	Up-regulation
Other_IKK_IKBKB_ST	Q99704	DOK1	O14920	IKBKB	S466	G464R	464	Missense	proximal	-2	no	18.191	17.253	EPSD	ICGC;COSMIC	16.613	Down-regulation
Other_IKK_IKBKB_ST	Q04206	RELA	O14920	IKBKB	S45	G48S	48	Missense	distal	3	no	17.029	18.264	EPSD;PhosphoSitePlus	ICGC;COSMIC	16.613	Up-regulation
Other_IKK_IKBKB_ST	Q04206	RELA	O14920	IKBKB	S45	R41H	41	Missense	distal	-4	no	17.029	17.332	EPSD;PhosphoSitePlus	ICGC;COSMIC	16.613	Up-regulation
Other_IKK_IKBKB_ST	Q04206	RELA	O14920	IKBKB	S112	H111N	111	Missense	proximal	-1	no	18.249	18.026	EPSD	ICGC	16.613	Down-regulation
Other_IKK_IKBKB_ST	Q04206	RELA	O14920	IKBKB	S112	H111Q	111	Missense	proximal	-1	no	18.249	18.625	EPSD	ICGC;COSMIC	16.613	Up-regulation
Other_IKK_IKBKB_ST	Q04206	RELA	O14920	IKBKB	S131	R133C	133	Missense	proximal	2	no	21.693	21.489	PhosphoSitePlus;EPSD	ICGC	16.613	Down-regulation
Other_IKK_IKBKB_ST	Q04206	RELA	O14920	IKBKB	S131	D125E	125	Missense	distal	-6	no	21.693	22.233	PhosphoSitePlus;EPSD	ICGC	16.613	Up-regulation
Other_IKK_IKBKB_ST	Q04206	RELA	O14920	IKBKB	S131	E127Q	127	Missense	distal	-4	no	21.693	16.830	PhosphoSitePlus;EPSD	ICGC;COSMIC	16.613	Down-regulation
Other_IKK_IKBKB_ST	Q04206	RELA	O14920	IKBKB	S311	P317H	317	Missense	distal	6	no	29.249	28.558	EPSD;PhosphoSitePlus	ICGC;COSMIC	16.613	Down-regulation
Other_IKK_IKBKB_ST	Q04206	RELA	O14920	IKBKB	S311	S311G	311	Missense	central	0	yes	29.249	0.000	EPSD;PhosphoSitePlus	ICGC;COSMIC	16.613	Loss
Other_IKK_IKBKB_ST	Q04206	RELA	O14920	IKBKB	S468	D470E	470	Missense	proximal	2	no	24.405	25.162	EPSD;PhosphoSitePlus	ICGC	16.613	Up-regulation
Other_IKK_IKBKB_ST	Q04206	RELA	O14920	IKBKB	S472	D470E	470	Missense	proximal	-2	no	20.019	20.066	EPSD	ICGC	16.613	Up-regulation
Other_IKK_IKBKB_ST	Q04206	RELA	O14920	IKBKB	S472	N479K	479	Missense	distal	7	no	20.019	20.805	EPSD	ICGC	16.613	Up-regulation
Other_IKK_IKBKB_ST	Q04206	RELA	O14920	IKBKB	S536	A538V	538	Missense	proximal	2	no	35.152	35.148	EPSD;PhosphoSitePlus	ICGC;COSMIC	16.613	Down-regulation
Other_IKK_IKBKB_ST	Q04206	RELA	O14920	IKBKB	S543	A538V	538	Missense	distal	-5	no	22.824	22.475	EPSD	ICGC;COSMIC	16.613	Down-regulation
Other_IKK_IKBKB_ST	Q04206	RELA	O14920	IKBKB	S543	Q548P	548	Missense	distal	5	no	22.824	22.001	EPSD	ICGC;COSMIC	16.613	Down-regulation
Other_IKK_IKBKB_ST	Q04206	RELA	O14920	IKBKB	S547	Q548P	548	Missense	proximal	1	no	20.261	20.165	EPSD	ICGC;COSMIC	16.613	Down-regulation
Other_IKK_IKBKB_ST	O15350	TP73	O14920	IKBKB	S471	S471R	471	Missense	central	0	yes	22.729	0.000	PhosphoSitePlus	ICGC;COSMIC	16.613	Loss
Other_IKK_IKBKB_ST	O15350	TP73	O14920	IKBKB	S471	S474F	474	Missense	distal	3	no	22.729	18.757	PhosphoSitePlus	ICGC	16.613	Down-regulation
Other_IKK_IKBKB_ST	Q9H3D4	TP63	O14920	IKBKB	S30	E33Q	33	Missense	distal	3	no	26.086	23.179	EPSD	ICGC;COSMIC;GDSC;CCLE	16.613	Down-regulation
Other_IKK_IKBKB_ST	Q9H3D4	TP63	O14920	IKBKB	S30	T25I	25	Missense	distal	-5	no	26.086	25.722	EPSD	ICGC;COSMIC	16.613	Down-regulation
Other_IKK_IKBKB_ST	Q9H3D4	TP63	O14920	IKBKB	S30	R37L	37	Missense	distal	7	no	26.086	25.959	EPSD	ICGC;COSMIC	16.613	Down-regulation
Other_IKK_IKBKB_ST	Q9H3D4	TP63	O14920	IKBKB	S30	W31L	31	Missense	proximal	1	no	26.086	25.179	EPSD	ICGC	16.613	Down-regulation
Other_IKK_IKBKB_ST	Q9H3D4	TP63	O14920	IKBKB	S30	E24D	24	Missense	distal	-6	no	26.086	25.546	EPSD	ICGC	16.613	Down-regulation
Other_IKK_IKBKB_ST	Q9H3D4	TP63	O14920	IKBKB	S43	R37L	37	Missense	distal	-6	no	18.071	18.095	EPSD;PhosphoSitePlus	ICGC;COSMIC	16.613	Up-regulation
Other_IKK_IKBKB_ST	Q9H3D4	TP63	O14920	IKBKB	S395	R393C	393	Missense	proximal	-2	no	23.136	23.876	EPSD	ICGC;COSMIC	16.613	Up-regulation
Other_IKK_IKBKB_ST	Q9H3D4	TP63	O14920	IKBKB	S395	R393S	393	Missense	proximal	-2	no	23.136	23.360	EPSD	ICGC	16.613	Up-regulation
Other_IKK_IKBKB_ST	Q9H3D4	TP63	O14920	IKBKB	S395	R393H	393	Missense	proximal	-2	no	23.136	23.653	EPSD	ICGC;COSMIC	16.613	Up-regulation
Other_IKK_IKBKB_ST	Q9H3D4	TP63	O14920	IKBKB	S395	T388P	388	Missense	distal	-7	no	23.136	21.496	EPSD	ICGC;COSMIC	16.613	Down-regulation
Other_IKK_IKBKB_ST	P19838	NFKB1	O14920	IKBKB	S80	S74I	74	Missense	distal	-6	no	17.328	16.116	EPSD	ICGC	16.613	Loss
Other_IKK_IKBKB_ST	P19838	NFKB1	O14920	IKBKB	S80	K78N	78	Missense	proximal	-2	no	17.328	17.835	EPSD	ICGC;COSMIC	16.613	Up-regulation
Other_IKK_IKBKB_ST	P19838	NFKB1	O14920	IKBKB	S80	P82H	82	Missense	proximal	2	no	17.328	17.459	EPSD	ICGC;COSMIC	16.613	Up-regulation
Other_IKK_IKBKB_ST	P19838	NFKB1	O14920	IKBKB	S449	S449R	449	Missense	central	0	yes	18.785	0.000	EPSD	ICGC;COSMIC	16.613	Loss
Other_IKK_IKBKB_ST	P19838	NFKB1	O14920	IKBKB	S907	Q900E	900	Missense	distal	-7	no	15.869	17.756	EPSD	ICGC;COSMIC	16.613	Gain
Other_IKK_IKBKB_ST	P19838	NFKB1	O14920	IKBKB	S923	S921I	921	Missense	proximal	-2	no	17.501	17.806	PhosphoSitePlus;EPSD	ICGC;COSMIC	16.613	Up-regulation
Other_IKK_IKBKB_ST	P19838	NFKB1	O14920	IKBKB	S923	D926N	926	Missense	distal	3	no	17.501	17.599	PhosphoSitePlus;EPSD	ICGC;COSMIC	16.613	Up-regulation
Other_IKK_IKBKB_ST	P19838	NFKB1	O14920	IKBKB	S927	R934L	934	Missense	distal	7	no	22.993	22.866	EPSD;PhosphoSitePlus	ICGC	16.613	Down-regulation
Other_IKK_IKBKB_ST	P19838	NFKB1	O14920	IKBKB	S927	S921I	921	Missense	distal	-6	no	22.993	21.781	EPSD;PhosphoSitePlus	ICGC;COSMIC	16.613	Down-regulation
Other_IKK_IKBKB_ST	P19838	NFKB1	O14920	IKBKB	S927	R934C	934	Missense	distal	7	no	22.993	22.491	EPSD;PhosphoSitePlus	ICGC;COSMIC	16.613	Down-regulation
Other_IKK_IKBKB_ST	P19838	NFKB1	O14920	IKBKB	S927	D926N	926	Missense	proximal	-1	no	22.993	22.546	EPSD;PhosphoSitePlus	ICGC;COSMIC	16.613	Down-regulation
Other_IKK_IKBKB_ST	P19838	NFKB1	O14920	IKBKB	S932	R934L	934	Missense	proximal	2	no	19.445	19.428	EPSD;PhosphoSitePlus	ICGC	16.613	Down-regulation
Other_IKK_IKBKB_ST	P19838	NFKB1	O14920	IKBKB	S932	R934C	934	Missense	proximal	2	no	19.445	19.241	EPSD;PhosphoSitePlus	ICGC;COSMIC	16.613	Down-regulation
Other_IKK_IKBKB_ST	P19838	NFKB1	O14920	IKBKB	S932	D926N	926	Missense	distal	-6	no	19.445	19.793	EPSD;PhosphoSitePlus	ICGC;COSMIC	16.613	Up-regulation
Other_IKK_IKBKB_ST	P19838	NFKB1	O14920	IKBKB	S941	R934L	934	Missense	distal	-7	no	18.040	16.274	EPSD	ICGC	16.613	Loss
Other_IKK_IKBKB_ST	P19838	NFKB1	O14920	IKBKB	S941	A946V	946	Missense	distal	5	no	18.040	16.319	EPSD	ICGC	16.613	Loss
Other_IKK_IKBKB_ST	P19838	NFKB1	O14920	IKBKB	S941	S944R	944	Missense	distal	3	no	18.040	16.698	EPSD	ICGC	16.613	Down-regulation
Other_IKK_IKBKB_ST	P19838	NFKB1	O14920	IKBKB	S941	R934C	934	Missense	distal	-7	no	18.040	16.224	EPSD	ICGC;COSMIC	16.613	Loss
Other_IKK_IKBKB_ST	P19838	NFKB1	O14920	IKBKB	S944	L951V	951	Missense	distal	7	no	25.368	24.615	EPSD	ICGC;COSMIC	16.613	Down-regulation
Other_IKK_IKBKB_ST	P19838	NFKB1	O14920	IKBKB	S944	A946V	946	Missense	proximal	2	no	25.368	25.365	EPSD	ICGC	16.613	Down-regulation
Other_IKK_IKBKB_ST	P19838	NFKB1	O14920	IKBKB	S944	S944R	944	Missense	central	0	yes	25.368	0.000	EPSD	ICGC	16.613	Loss
Other_IKK_IKBKB_ST	P25963	NFKBIA	O14920	IKBKB	S32	R29S	29	Missense	distal	-3	no	36.028	35.868	EPSD;PhosphoSitePlus	ICGC	16.613	Down-regulation
Other_IKK_IKBKB_ST	P25963	NFKBIA	O14920	IKBKB	S32	D31G	31	Missense	proximal	-1	no	36.028	36.116	EPSD;PhosphoSitePlus	ICGC;COSMIC	16.613	Up-regulation
Other_IKK_IKBKB_ST	P25963	NFKBIA	O14920	IKBKB	S32	K38T	38	Missense	distal	6	no	36.028	37.134	EPSD;PhosphoSitePlus	ICGC	16.613	Up-regulation
Other_IKK_IKBKB_ST	P25963	NFKBIA	O14920	IKBKB	S36	R29S	29	Missense	distal	-7	no	37.410	36.942	PhosphoSitePlus;EPSD	ICGC	16.613	Down-regulation
Other_IKK_IKBKB_ST	P25963	NFKBIA	O14920	IKBKB	S36	D31G	31	Missense	distal	-5	no	37.410	37.325	PhosphoSitePlus;EPSD	ICGC;COSMIC	16.613	Down-regulation
Other_IKK_IKBKB_ST	P25963	NFKBIA	O14920	IKBKB	S36	K38T	38	Missense	proximal	2	no	37.410	36.757	PhosphoSitePlus;EPSD	ICGC	16.613	Down-regulation
Other_IKK_IKBKB_ST	P01100	FOS	O14920	IKBKB	S32	S26I	26	Missense	distal	-6	no	19.345	18.134	EPSD	ICGC	16.613	Down-regulation
Other_IKK_IKBKB_ST	P01100	FOS	O14920	IKBKB	S281	R287H	287	Missense	distal	6	no	18.030	18.040	EPSD	ICGC;COSMIC	16.613	Up-regulation
Other_IKK_IKBKB_ST	P01100	FOS	O14920	IKBKB	S308	A301T	301	Missense	distal	-7	no	27.703	27.272	PhosphoSitePlus	ICGC;CCLE	16.613	Down-regulation
Other_IKK_IKBKB_ST	Q01201	RELB	O14920	IKBKB	S41	V47F	47	Missense	distal	6	no	21.787	21.870	EPSD	ICGC;COSMIC	16.613	Up-regulation
Other_IKK_IKBKB_ST	Q01201	RELB	O14920	IKBKB	S48	V47F	47	Missense	proximal	-1	no	23.926	24.121	EPSD	ICGC;COSMIC	16.613	Up-regulation
Other_IKK_IKBKB_ST	Q92574	TSC1	O14920	IKBKB	S108	Q109K	109	Missense	proximal	1	no	21.638	19.029	EPSD	ICGC	16.613	Down-regulation
Other_IKK_IKBKB_ST	Q92574	TSC1	O14920	IKBKB	S276	G274A	274	Missense	proximal	-2	no	18.671	17.515	EPSD	ICGC;COSMIC	16.613	Down-regulation
Other_IKK_IKBKB_ST	Q92574	TSC1	O14920	IKBKB	S295	S289L	289	Missense	distal	-6	no	21.638	21.003	EPSD	ICGC;COSMIC	16.613	Down-regulation
Other_IKK_IKBKB_ST	Q92574	TSC1	O14920	IKBKB	S295	D299E	299	Missense	distal	4	no	21.638	26.425	EPSD	ICGC	16.613	Up-regulation
Other_IKK_IKBKB_ST	Q92574	TSC1	O14920	IKBKB	S295	T293N	293	Missense	proximal	-2	no	21.638	21.782	EPSD	ICGC	16.613	Up-regulation
Other_IKK_IKBKB_ST	Q92574	TSC1	O14920	IKBKB	S427	H433N	433	Missense	distal	6	no	17.786	18.560	EPSD	ICGC	16.613	Up-regulation
Other_IKK_IKBKB_ST	Q92574	TSC1	O14920	IKBKB	S427	E423V	423	Missense	distal	-4	no	17.786	6.250	EPSD	ICGC;COSMIC	16.613	Loss
Other_IKK_IKBKB_ST	Q92574	TSC1	O14920	IKBKB	S483	R484I	484	Missense	proximal	1	no	22.413	24.184	EPSD	ICGC;COSMIC	16.613	Up-regulation
Other_IKK_IKBKB_ST	Q92574	TSC1	O14920	IKBKB	S487	E493Q	493	Missense	distal	6	no	18.619	18.170	PhosphoSitePlus;EPSD	ICGC;COSMIC	16.613	Down-regulation
Other_IKK_IKBKB_ST	Q92574	TSC1	O14920	IKBKB	S487	A492E	492	Missense	distal	5	no	18.619	19.973	PhosphoSitePlus;EPSD	ICGC	16.613	Up-regulation
Other_IKK_IKBKB_ST	Q92574	TSC1	O14920	IKBKB	S487	R484I	484	Missense	distal	-3	no	18.619	17.523	PhosphoSitePlus;EPSD	ICGC;COSMIC	16.613	Down-regulation
Other_IKK_IKBKB_ST	Q92574	TSC1	O14920	IKBKB	S511	R517Q	517	Missense	distal	6	no	26.545	26.897	EPSD;PhosphoSitePlus	ICGC;COSMIC	16.613	Up-regulation
Other_IKK_IKBKB_ST	Q92574	TSC1	O14920	IKBKB	S521	R517Q	517	Missense	distal	-4	no	17.930	16.677	EPSD	ICGC;COSMIC	16.613	Down-regulation
Other_IKK_IKBKB_ST	Q92574	TSC1	O14920	IKBKB	S526	A529V	529	Missense	distal	3	no	19.060	15.179	EPSD	ICGC;COSMIC	16.613	Loss
Other_IKK_IKBKB_ST	Q92574	TSC1	O14920	IKBKB	S530	A529V	529	Missense	proximal	-1	no	19.116	19.535	EPSD	ICGC;COSMIC	16.613	Up-regulation
Other_IKK_IKBKB_ST	Q92574	TSC1	O14920	IKBKB	S539	D546E	546	Missense	distal	7	no	16.590	17.688	EPSD	ICGC	16.613	Gain
Other_IKK_IKBKB_ST	Q92574	TSC1	O14920	IKBKB	S575	Q573H	573	Missense	proximal	-2	no	26.423	26.533	EPSD	ICGC;COSMIC	16.613	Up-regulation
Other_IKK_IKBKB_ST	Q92574	TSC1	O14920	IKBKB	S579	P583H	583	Missense	distal	4	no	19.544	18.274	EPSD	ICGC;COSMIC	16.613	Down-regulation
Other_IKK_IKBKB_ST	Q92574	TSC1	O14920	IKBKB	S579	Q573H	573	Missense	distal	-6	no	19.544	20.449	EPSD	ICGC;COSMIC	16.613	Up-regulation
Other_IKK_IKBKB_ST	Q92574	TSC1	O14920	IKBKB	S644	V640M	640	Missense	distal	-4	no	9.230	19.993	EPSD	ICGC	16.613	Gain
Other_IKK_IKBKB_ST	Q92574	TSC1	O14920	IKBKB	S1038	S1043N	1043	Missense	distal	5	no	20.599	19.145	EPSD	ICGC;COSMIC	16.613	Down-regulation
Other_IKK_IKBKB_ST	Q92574	TSC1	O14920	IKBKB	S1038	S1038R	1038	Missense	central	0	yes	20.599	0.000	EPSD	ICGC;COSMIC	16.613	Loss
Other_IKK_IKBKB_ST	Q92574	TSC1	O14920	IKBKB	S1038	S1039G	1039	Missense	proximal	1	no	20.599	22.106	EPSD	ICGC;COSMIC	16.613	Up-regulation
Other_IKK_IKBKB_ST	Q92574	TSC1	O14920	IKBKB	S1039	S1043N	1043	Missense	distal	4	no	22.000	19.133	EPSD	ICGC;COSMIC	16.613	Down-regulation
Other_IKK_IKBKB_ST	Q92574	TSC1	O14920	IKBKB	S1039	S1038R	1038	Missense	proximal	-1	no	22.000	22.166	EPSD	ICGC;COSMIC	16.613	Up-regulation
Other_IKK_IKBKB_ST	Q92574	TSC1	O14920	IKBKB	S1039	S1039G	1039	Missense	central	0	yes	22.000	0.000	EPSD	ICGC;COSMIC	16.613	Loss
Other_IKK_IKBKB_ST	Q92574	TSC1	O14920	IKBKB	S1042	S1043N	1043	Missense	proximal	1	no	16.084	16.799	EPSD	ICGC;COSMIC	16.613	Gain
Other_IKK_IKBKB_ST	Q92574	TSC1	O14920	IKBKB	S1046	S1043N	1043	Missense	distal	-3	no	24.987	25.364	EPSD	ICGC;COSMIC	16.613	Up-regulation
Other_IKK_IKBKB_ST	Q92574	TSC1	O14920	IKBKB	S1046	P1048T	1048	Missense	proximal	2	no	24.987	25.365	EPSD	ICGC;COSMIC	16.613	Up-regulation
Other_IKK_IKBKB_ST	Q92574	TSC1	O14920	IKBKB	S1046	S1039G	1039	Missense	distal	-7	no	24.987	25.208	EPSD	ICGC;COSMIC	16.613	Up-regulation
Other_IKK_IKBKB_ST	Q92574	TSC1	O14920	IKBKB	S1086	G1089C	1089	Missense	distal	3	no	23.489	21.743	EPSD	ICGC;COSMIC	16.613	Down-regulation
Other_IKK_IKBKB_ST	O95999	BCL10	O14920	IKBKB	S121	L114M	114	Missense	distal	-7	no	16.148	18.510	EPSD	ICGC;COSMIC	16.613	Gain
Other_IKK_IKBKB_ST	O95999	BCL10	O14920	IKBKB	S134	N132S	132	Missense	proximal	-2	no	20.709	20.792	EPSD;PhosphoSitePlus	ICGC;COSMIC	16.613	Up-regulation
Other_IKK_IKBKB_ST	O95999	BCL10	O14920	IKBKB	S134	S134F	134	Missense	central	0	yes	20.709	0.000	EPSD;PhosphoSitePlus	ICGC	16.613	Loss
Other_IKK_IKBKB_ST	O95999	BCL10	O14920	IKBKB	S136	N132S	132	Missense	distal	-4	no	32.835	36.541	EPSD;PhosphoSitePlus	ICGC;COSMIC	16.613	Up-regulation
Other_IKK_IKBKB_ST	O95999	BCL10	O14920	IKBKB	S136	S134F	134	Missense	proximal	-2	no	32.835	33.573	EPSD;PhosphoSitePlus	ICGC	16.613	Up-regulation
Other_IKK_IKBKB_ST	O95999	BCL10	O14920	IKBKB	S138	N132S	132	Missense	distal	-6	no	28.430	28.307	PhosphoSitePlus;EPSD	ICGC;COSMIC	16.613	Down-regulation
Other_IKK_IKBKB_ST	O95999	BCL10	O14920	IKBKB	S138	S134F	134	Missense	distal	-4	no	28.430	22.196	PhosphoSitePlus;EPSD	ICGC	16.613	Down-regulation
Other_IKK_IKBKB_ST	O95999	BCL10	O14920	IKBKB	S141	S134F	134	Missense	distal	-7	no	25.356	23.174	EPSD;PhosphoSitePlus	ICGC	16.613	Down-regulation
Other_IKK_IKBKB_ST	O95999	BCL10	O14920	IKBKB	S167	T162M	162	Missense	distal	-5	no	16.643	16.674	EPSD	ICGC;COSMIC;GDSC	16.613	Up-regulation
Other_IKK_IKBKB_ST	O95999	BCL10	O14920	IKBKB	S167	S161R	161	Missense	distal	-6	no	16.643	15.985	EPSD	ICGC	16.613	Loss
Other_IKK_IKBKB_ST	O95999	BCL10	O14920	IKBKB	S167	N173H	173	Missense	distal	6	no	16.643	15.869	EPSD	ICGC;COSMIC	16.613	Loss
Other_IKK_IKBKB_ST	O95999	BCL10	O14920	IKBKB	S170	N173H	173	Missense	distal	3	no	16.668	16.222	EPSD	ICGC;COSMIC	16.613	Loss
Other_IKK_IKBKB_ST	O95999	BCL10	O14920	IKBKB	S218	G213E	213	Missense	distal	-5	no	19.414	19.505	EPSD	ICGC;COSMIC	16.613	Up-regulation
Other_IKK_IKBKB_ST	O95999	BCL10	O14920	IKBKB	S218	P224L	224	Missense	distal	6	no	19.414	19.296	EPSD	ICGC;GDSC;CCLE	16.613	Down-regulation
Other_IKK_IKBKB_ST	P42858	HTT	O14920	IKBKB	S13	A10S	10	Missense	distal	-3	no	20.706	20.575	PhosphoSitePlus;EPSD	ICGC	16.613	Down-regulation
Other_IKK_IKBKB_ST	P42858	HTT	O14920	IKBKB	S13	S13C	13	Missense	central	0	yes	20.706	0.000	PhosphoSitePlus;EPSD	ICGC;COSMIC	16.613	Loss
Other_IKK_IKBKB_ST	P42858	HTT	O14920	IKBKB	S16	A10S	10	Missense	distal	-6	no	19.684	19.640	EPSD;PhosphoSitePlus	ICGC	16.613	Down-regulation
Other_IKK_IKBKB_ST	P42858	HTT	O14920	IKBKB	S16	S13C	13	Missense	distal	-3	no	19.684	19.264	EPSD;PhosphoSitePlus	ICGC;COSMIC	16.613	Down-regulation
Other_IKK_IKBKB_ST	P42858	HTT	O14920	IKBKB	S415	I420V	420	Missense	distal	5	no	25.554	26.501	EPSD	ICGC;COSMIC	16.613	Up-regulation
Other_IKK_IKBKB_ST	P42858	HTT	O14920	IKBKB	S415	G412C	412	Missense	distal	-3	no	25.554	25.401	EPSD	ICGC;COSMIC	16.613	Down-regulation
Other_IKK_IKBKB_ST	P42858	HTT	O14920	IKBKB	S419	I420V	420	Missense	proximal	1	no	17.051	14.800	EPSD	ICGC;COSMIC	16.613	Loss
Other_IKK_IKBKB_ST	P42858	HTT	O14920	IKBKB	S419	G412C	412	Missense	distal	-7	no	17.051	15.482	EPSD	ICGC;COSMIC	16.613	Loss
Other_IKK_IKBKB_ST	P42858	HTT	O14920	IKBKB	S459	E452D	452	Missense	distal	-7	no	21.565	21.088	EPSD	ICGC;COSMIC	16.613	Down-regulation
Other_IKK_IKBKB_ST	P42858	HTT	O14920	IKBKB	S459	S459L	459	Missense	central	0	yes	21.565	0.000	EPSD	ICGC;COSMIC	16.613	Loss
Other_IKK_IKBKB_ST	P42858	HTT	O14920	IKBKB	S1111	W1109C	1109	Missense	proximal	-2	no	20.466	20.526	EPSD	ICGC;COSMIC	16.613	Up-regulation
Other_IKK_IKBKB_ST	P42858	HTT	O14920	IKBKB	S1111	L1105M	1105	Missense	distal	-6	no	20.466	21.428	EPSD	ICGC;COSMIC	16.613	Up-regulation
Other_IKK_IKBKB_ST	P42858	HTT	O14920	IKBKB	S1111	P1117Q	1117	Missense	distal	6	no	20.466	20.118	EPSD	ICGC;COSMIC	16.613	Down-regulation
Other_IKK_IKBKB_ST	P42858	HTT	O14920	IKBKB	S1179	R1183Q	1183	Missense	distal	4	no	17.540	19.534	EPSD	ICGC;COSMIC	16.613	Up-regulation
Other_IKK_IKBKB_ST	P42858	HTT	O14920	IKBKB	S1199	S1199I	1199	Missense	central	0	yes	18.582	0.000	EPSD	ICGC	16.613	Loss
Other_IKK_IKBKB_ST	P42858	HTT	O14920	IKBKB	S1199	P1197L	1197	Missense	proximal	-2	no	18.582	18.467	EPSD	ICGC;COSMIC	16.613	Down-regulation
Other_IKK_IKBKB_ST	P42858	HTT	O14920	IKBKB	S1862	P1858L	1858	Missense	distal	-4	no	17.613	14.504	EPSD	ICGC;COSMIC	16.613	Loss
Other_IKK_IKBKB_ST	P42858	HTT	O14920	IKBKB	S1864	P1858L	1858	Missense	distal	-6	no	20.005	19.630	EPSD	ICGC;COSMIC	16.613	Down-regulation
Other_IKK_IKBKB_ST	P42858	HTT	O14920	IKBKB	S1865	P1858L	1858	Missense	distal	-7	no	16.705	16.681	EPSD	ICGC;COSMIC	16.613	Down-regulation
Other_IKK_IKBKB_ST	P42858	HTT	O14920	IKBKB	S1870	E1876A	1876	Missense	distal	6	no	20.572	20.363	EPSD	ICGC	16.613	Down-regulation
Other_IKK_IKBKB_ST	P42858	HTT	O14920	IKBKB	S1874	E1876A	1876	Missense	proximal	2	no	20.141	19.773	EPSD	ICGC	16.613	Down-regulation
Other_IKK_IKBKB_ST	P42858	HTT	O14920	IKBKB	S2074	S2074Y	2074	Missense	central	0	yes	18.883	0.000	EPSD	ICGC;COSMIC	16.613	Loss
Other_IKK_IKBKB_ST	P42858	HTT	O14920	IKBKB	S2074	S2072I	2072	Missense	proximal	-2	no	18.883	19.188	EPSD	ICGC	16.613	Up-regulation
Other_IKK_IKBKB_ST	P42858	HTT	O14920	IKBKB	S2157	S2154N	2154	Missense	distal	-3	no	16.835	17.212	EPSD	ICGC;COSMIC	16.613	Up-regulation
Other_IKK_IKBKB_ST	P42858	HTT	O14920	IKBKB	S2157	S2154I	2154	Missense	distal	-3	no	16.835	15.900	EPSD	ICGC;COSMIC	16.613	Loss
Other_IKK_IKBKB_ST	P42858	HTT	O14920	IKBKB	S2328	Q2325H	2325	Missense	distal	-3	no	18.309	18.257	EPSD	ICGC;COSMIC	16.613	Down-regulation
Other_IKK_IKBKB_ST	P42858	HTT	O14920	IKBKB	S2651	P2656T	2656	Missense	distal	5	no	16.872	16.351	EPSD	ICGC;COSMIC	16.613	Loss
Other_IKK_IKBKB_ST	P42858	HTT	O14920	IKBKB	S2655	P2656T	2656	Missense	proximal	1	no	21.289	19.527	EPSD	ICGC;COSMIC	16.613	Down-regulation
Other_IKK_IKBKB_ST	P42858	HTT	O14920	IKBKB	S2764	A2760V	2760	Missense	distal	-4	no	16.973	10.879	EPSD	ICGC;COSMIC	16.613	Loss
Other_IKK_IKBKB_ST	P42858	HTT	O14920	IKBKB	S2934	T2938S	2938	Missense	distal	4	no	14.413	17.917	EPSD	ICGC	16.613	Gain
Other_IKK_IKBKB_ST	P42858	HTT	O14920	IKBKB	S3030	W3035L	3035	Missense	distal	5	no	16.413	20.647	EPSD	ICGC	16.613	Gain
Other_IKK_IKBKB_ST	Q6P2E9	EDC4	O14920	IKBKB	S103	S107I	107	Missense	distal	4	no	16.885	11.720	EPSD	ICGC	16.613	Loss
Other_IKK_IKBKB_ST	Q6P2E9	EDC4	O14920	IKBKB	S103	E97D	97	Missense	distal	-6	no	16.885	16.345	EPSD	ICGC;COSMIC	16.613	Loss
Other_IKK_IKBKB_ST	Q6P2E9	EDC4	O14920	IKBKB	S103	S107N	107	Missense	distal	4	no	16.885	14.019	EPSD	ICGC;COSMIC	16.613	Loss
Other_IKK_IKBKB_ST	Q6P2E9	EDC4	O14920	IKBKB	S106	S107I	107	Missense	proximal	1	no	18.656	20.819	EPSD	ICGC	16.613	Up-regulation
Other_IKK_IKBKB_ST	Q6P2E9	EDC4	O14920	IKBKB	S106	S107N	107	Missense	proximal	1	no	18.656	19.371	EPSD	ICGC;COSMIC	16.613	Up-regulation
Other_IKK_IKBKB_ST	Q6P2E9	EDC4	O14920	IKBKB	S107	S107I	107	Missense	central	0	yes	18.539	0.000	EPSD;PhosphoSitePlus	ICGC	16.613	Loss
Other_IKK_IKBKB_ST	Q6P2E9	EDC4	O14920	IKBKB	S107	S107N	107	Missense	central	0	yes	18.539	0.000	EPSD;PhosphoSitePlus	ICGC;COSMIC	16.613	Loss
Other_IKK_IKBKB_ST	Q6P2E9	EDC4	O14920	IKBKB	S613	Q607H	607	Missense	distal	-6	no	21.529	22.435	EPSD	ICGC;COSMIC	16.613	Up-regulation
Other_IKK_IKBKB_ST	Q6P2E9	EDC4	O14920	IKBKB	S622	S629F	629	Missense	distal	7	no	20.619	19.601	EPSD	ICGC;COSMIC	16.613	Down-regulation
Other_IKK_IKBKB_ST	Q6P2E9	EDC4	O14920	IKBKB	S623	S629F	629	Missense	distal	6	no	24.194	26.287	EPSD	ICGC;COSMIC	16.613	Up-regulation
Other_IKK_IKBKB_ST	Q6P2E9	EDC4	O14920	IKBKB	S624	S629F	629	Missense	distal	5	no	19.488	17.543	EPSD	ICGC;COSMIC	16.613	Down-regulation
Other_IKK_IKBKB_ST	Q6P2E9	EDC4	O14920	IKBKB	S645	S645C	645	Missense	central	0	yes	17.142	0.000	EPSD	ICGC;COSMIC	16.613	Loss
Other_IKK_IKBKB_ST	Q6P2E9	EDC4	O14920	IKBKB	S645	P650R	650	Missense	distal	5	no	17.142	16.244	EPSD	ICGC;COSMIC	16.613	Loss
Other_IKK_IKBKB_ST	Q6P2E9	EDC4	O14920	IKBKB	S645	S638I	638	Missense	distal	-7	no	17.142	14.899	EPSD	ICGC;COSMIC	16.613	Loss
Other_IKK_IKBKB_ST	Q6P2E9	EDC4	O14920	IKBKB	S664	S670N	670	Missense	distal	6	no	17.590	18.998	EPSD	ICGC	16.613	Up-regulation
Other_IKK_IKBKB_ST	Q6P2E9	EDC4	O14920	IKBKB	S664	G663C	663	Missense	proximal	-1	no	17.590	17.500	EPSD	ICGC;COSMIC	16.613	Down-regulation
Other_IKK_IKBKB_ST	Q6P2E9	EDC4	O14920	IKBKB	S670	S670N	670	Missense	central	0	yes	23.996	0.000	EPSD	ICGC	16.613	Loss
Other_IKK_IKBKB_ST	Q6P2E9	EDC4	O14920	IKBKB	S670	A675G	675	Missense	distal	5	no	23.996	20.368	EPSD	ICGC;COSMIC	16.613	Down-regulation
Other_IKK_IKBKB_ST	Q6P2E9	EDC4	O14920	IKBKB	S670	G663C	663	Missense	distal	-7	no	23.996	22.427	EPSD	ICGC;COSMIC	16.613	Down-regulation
Other_IKK_IKBKB_ST	Q6P2E9	EDC4	O14920	IKBKB	S672	S670N	670	Missense	proximal	-2	no	18.921	18.838	EPSD	ICGC	16.613	Down-regulation
Other_IKK_IKBKB_ST	Q6P2E9	EDC4	O14920	IKBKB	S672	A675G	675	Missense	distal	3	no	18.921	19.128	EPSD	ICGC;COSMIC	16.613	Up-regulation
Other_IKK_IKBKB_ST	Q6P2E9	EDC4	O14920	IKBKB	S676	S670N	670	Missense	distal	-6	no	19.512	19.636	EPSD	ICGC	16.613	Up-regulation
Other_IKK_IKBKB_ST	Q6P2E9	EDC4	O14920	IKBKB	S676	A675G	675	Missense	proximal	-1	no	19.512	20.059	EPSD	ICGC;COSMIC	16.613	Up-regulation
Other_IKK_IKBKB_ST	Q6P2E9	EDC4	O14920	IKBKB	S734	S735L	735	Missense	proximal	1	no	18.167	18.936	EPSD	ICGC	16.613	Up-regulation
Other_IKK_IKBKB_ST	Q6P2E9	EDC4	O14920	IKBKB	S735	S735L	735	Missense	central	0	yes	18.217	0.000	EPSD	ICGC	16.613	Loss
Other_IKK_IKBKB_ST	Q6P2E9	EDC4	O14920	IKBKB	S771	A773T	773	Missense	proximal	2	no	18.572	18.408	EPSD	ICGC;COSMIC	16.613	Down-regulation
Other_IKK_IKBKB_ST	Q6P2E9	EDC4	O14920	IKBKB	S809	P808L	808	Missense	proximal	-1	no	17.684	17.528	EPSD	ICGC	16.613	Down-regulation
Other_IKK_IKBKB_ST	Q6P2E9	EDC4	O14920	IKBKB	S839	L841P	841	Missense	proximal	2	no	20.243	20.107	EPSD	ICGC	16.613	Down-regulation
Other_IKK_IKBKB_ST	Q6P2E9	EDC4	O14920	IKBKB	S839	A842S	842	Missense	distal	3	no	20.243	21.685	EPSD	ICGC	16.613	Up-regulation
Other_IKK_IKBKB_ST	Q6P2E9	EDC4	O14920	IKBKB	S839	L841M	841	Missense	proximal	2	no	20.243	21.316	EPSD	ICGC;COSMIC	16.613	Up-regulation
Other_IKK_IKBKB_ST	Q6P2E9	EDC4	O14920	IKBKB	S875	R869H	869	Missense	distal	-6	no	16.316	16.862	EPSD	ICGC;COSMIC	16.613	Gain
Other_IKK_IKBKB_ST	Q6P2E9	EDC4	O14920	IKBKB	S879	E884Q	884	Missense	distal	5	no	17.167	16.120	EPSD	ICGC;COSMIC	16.613	Loss
Other_IKK_IKBKB_ST	Q6P2E9	EDC4	O14920	IKBKB	S879	Q872H	872	Missense	distal	-7	no	17.167	17.500	EPSD	ICGC	16.613	Up-regulation
Other_IKK_IKBKB_ST	Q6P2E9	EDC4	O14920	IKBKB	S887	E884Q	884	Missense	distal	-3	no	19.001	18.881	EPSD	ICGC;COSMIC	16.613	Down-regulation
Other_IKK_IKBKB_ST	Q6P2E9	EDC4	O14920	IKBKB	S918	K922R	922	Missense	distal	4	no	16.950	15.309	EPSD	ICGC;COSMIC	16.613	Loss
Other_IKK_IKBKB_ST	Q6P2E9	EDC4	O14920	IKBKB	S936	D931V	931	Missense	distal	-5	no	19.893	19.557	EPSD	ICGC;COSMIC	16.613	Down-regulation
Other_IKK_IKBKB_ST	Q6P2E9	EDC4	O14920	IKBKB	S967	R965L	965	Missense	proximal	-2	no	18.309	19.305	EPSD	ICGC;COSMIC	16.613	Up-regulation
Other_IKK_IKBKB_ST	Q6P2E9	EDC4	O14920	IKBKB	S967	R974H	974	Missense	distal	7	no	18.309	18.061	EPSD	ICGC;COSMIC	16.613	Down-regulation
Other_IKK_IKBKB_ST	Q6P2E9	EDC4	O14920	IKBKB	S1058	P1052H	1052	Missense	distal	-6	no	19.010	19.158	EPSD	ICGC;COSMIC	16.613	Up-regulation
Other_IKK_IKBKB_ST	Q6P2E9	EDC4	O14920	IKBKB	S1058	P1053Q	1053	Missense	distal	-5	no	19.010	18.439	EPSD	ICGC;COSMIC	16.613	Down-regulation
Other_IKK_IKBKB_ST	Q6P2E9	EDC4	O14920	IKBKB	S1069	A1071S	1071	Missense	proximal	2	no	21.398	21.113	EPSD	ICGC	16.613	Down-regulation
Other_IKK_IKBKB_ST	Q6P2E9	EDC4	O14920	IKBKB	S1154	L1152I	1152	Missense	proximal	-2	no	19.924	19.457	EPSD	ICGC;COSMIC	16.613	Down-regulation
Other_IKK_IKBKB_ST	Q6P2E9	EDC4	O14920	IKBKB	S1154	L1149F	1149	Missense	distal	-5	no	19.924	19.742	EPSD	ICGC;COSMIC	16.613	Down-regulation
Other_IKK_IKBKB_ST	Q6P2E9	EDC4	O14920	IKBKB	S1158	L1152I	1152	Missense	distal	-6	no	26.098	25.522	EPSD	ICGC;COSMIC	16.613	Down-regulation
Other_IKK_IKBKB_ST	Q6P2E9	EDC4	O14920	IKBKB	S1158	E1165K	1165	Missense	distal	7	no	26.098	25.801	EPSD	ICGC;COSMIC	16.613	Down-regulation
Other_IKK_IKBKB_ST	Q6P2E9	EDC4	O14920	IKBKB	S1380	A1375S	1375	Missense	distal	-5	no	18.886	18.916	EPSD	ICGC;COSMIC	16.613	Up-regulation
Other_IKK_IKBKB_ST	P42771	CDKN2A	O14920	IKBKB	S8	E10K	10	Missense	proximal	2	no	17.179	17.301	PhosphoSitePlus	ICGC;COSMIC	16.613	Up-regulation
Other_IKK_IKBKB_ST	P42771	CDKN2A	O14920	IKBKB	S56	I49N	49	Missense	distal	-7	no	13.964	17.399	EPSD	ICGC;COSMIC	16.613	Gain
Other_IKK_IKBKB_ST	Q9Y6K9	IKBKG	O14920	IKBKB	S43	L39M	39	Missense	distal	-4	no	16.039	23.197	EPSD;PhosphoSitePlus	ICGC;COSMIC	16.613	Gain
Other_IKK_IKBKB_ST	Q9Y6K9	IKBKG	O14920	IKBKB	S148	T147K	147	Missense	proximal	-1	no	26.848	26.787	EPSD	ICGC;COSMIC	16.613	Down-regulation
Other_IKK_IKBKB_ST	P21580	TNFAIP3	O14920	IKBKB	S128	F127C	127	Missense	proximal	-1	no	20.968	20.813	EPSD	ICGC;COSMIC	16.613	Down-regulation
Other_IKK_IKBKB_ST	P21580	TNFAIP3	O14920	IKBKB	S573	D566Y	566	Missense	distal	-7	no	20.858	18.033	EPSD	ICGC;COSMIC	16.613	Down-regulation
Other_IKK_IKBKB_ST	P21580	TNFAIP3	O14920	IKBKB	S573	R572W	572	Missense	proximal	-1	no	20.858	21.347	EPSD	ICGC	16.613	Up-regulation
Other_IKK_IKBKB_ST	P21580	TNFAIP3	O14920	IKBKB	S573	V571F	571	Missense	proximal	-2	no	20.858	22.052	EPSD	ICGC	16.613	Up-regulation
Other_IKK_IKBKB_ST	P21580	TNFAIP3	O14920	IKBKB	S645	S641A	641	Missense	distal	-4	no	18.626	14.484	EPSD	ICGC;COSMIC	16.613	Loss
Other_IKK_IKBKB_ST	P21580	TNFAIP3	O14920	IKBKB	S645	G642V	642	Missense	distal	-3	no	18.626	18.565	EPSD	ICGC;COSMIC	16.613	Down-regulation
Other_IKK_IKBKB_ST	P21580	TNFAIP3	O14920	IKBKB	S645	V644F	644	Missense	proximal	-1	no	18.626	18.820	EPSD	ICGC	16.613	Up-regulation
Other_IKK_IKBKB_ST	P21580	TNFAIP3	O14920	IKBKB	S645	S649P	649	Missense	distal	4	no	18.626	16.426	EPSD	ICGC	16.613	Loss
Other_IKK_IKBKB_ST	P21580	TNFAIP3	O14920	IKBKB	S645	A638D	638	Missense	distal	-7	no	18.626	18.180	EPSD	ICGC	16.613	Down-regulation
Other_IKK_IKBKB_ST	P21580	TNFAIP3	O14920	IKBKB	S698	R701C	701	Missense	distal	3	no	18.728	17.090	EPSD	ICGC;COSMIC	16.613	Down-regulation
Other_IKK_IKBKB_ST	Q9Y4G8	RAPGEF2	O14920	IKBKB	S501	A506S	506	Missense	distal	5	no	16.948	16.632	EPSD	ICGC	16.613	Down-regulation
Other_IKK_IKBKB_ST	Q9Y4G8	RAPGEF2	O14920	IKBKB	S592	R595L	595	Missense	distal	3	no	18.810	17.201	EPSD	ICGC	16.613	Down-regulation
Other_IKK_IKBKB_ST	Q9Y4G8	RAPGEF2	O14920	IKBKB	S806	I810M	810	Missense	distal	4	no	11.282	18.778	EPSD	ICGC;COSMIC	16.613	Gain
Other_IKK_IKBKB_ST	Q9Y4G8	RAPGEF2	O14920	IKBKB	S912	V907L	907	Missense	distal	-5	no	17.157	17.480	EPSD	ICGC;COSMIC	16.613	Up-regulation
Other_IKK_IKBKB_ST	Q9Y4G8	RAPGEF2	O14920	IKBKB	S912	A918T	918	Missense	distal	6	no	17.157	16.756	EPSD	ICGC;COSMIC	16.613	Down-regulation
Other_IKK_IKBKB_ST	Q9Y4G8	RAPGEF2	O14920	IKBKB	S912	V907I	907	Missense	distal	-5	no	17.157	17.208	EPSD	ICGC;COSMIC	16.613	Up-regulation
Other_IKK_IKBKB_ST	Q9Y4G8	RAPGEF2	O14920	IKBKB	S912	S912L	912	Missense	central	0	yes	17.157	0.000	EPSD	ICGC	16.613	Loss
Other_IKK_IKBKB_ST	Q9Y4G8	RAPGEF2	O14920	IKBKB	S1019	V1024A	1024	Missense	distal	5	no	19.427	21.149	EPSD	ICGC;COSMIC	16.613	Up-regulation
Other_IKK_IKBKB_ST	Q9Y4G8	RAPGEF2	O14920	IKBKB	S1022	V1024A	1024	Missense	proximal	2	no	18.520	18.523	EPSD	ICGC;COSMIC	16.613	Up-regulation
Other_IKK_IKBKB_ST	Q9Y4G8	RAPGEF2	O14920	IKBKB	S1089	L1090F	1090	Missense	proximal	1	no	27.957	29.103	EPSD	ICGC	16.613	Up-regulation
Other_IKK_IKBKB_ST	Q9Y4G8	RAPGEF2	O14920	IKBKB	S1095	L1090F	1090	Missense	distal	-5	no	19.879	19.698	EPSD	ICGC	16.613	Down-regulation
Other_IKK_IKBKB_ST	Q9Y4G8	RAPGEF2	O14920	IKBKB	S1108	S1112L	1112	Missense	distal	4	no	21.384	19.539	EPSD	ICGC;COSMIC	16.613	Down-regulation
Other_IKK_IKBKB_ST	Q9Y4G8	RAPGEF2	O14920	IKBKB	S1108	E1104A	1104	Missense	distal	-4	no	21.384	15.943	EPSD	ICGC	16.613	Loss
Other_IKK_IKBKB_ST	Q9Y4G8	RAPGEF2	O14920	IKBKB	S1112	S1112L	1112	Missense	central	0	yes	30.875	0.000	EPSD	ICGC;COSMIC	16.613	Loss
Other_IKK_IKBKB_ST	Q9Y4G8	RAPGEF2	O14920	IKBKB	S1115	S1112L	1112	Missense	distal	-3	no	18.345	17.936	EPSD	ICGC;COSMIC	16.613	Down-regulation
Other_IKK_IKBKB_ST	Q9Y4G8	RAPGEF2	O14920	IKBKB	S1116	S1112L	1112	Missense	distal	-4	no	21.270	14.638	EPSD	ICGC;COSMIC	16.613	Loss
Other_IKK_IKBKB_ST	Q9Y4G8	RAPGEF2	O14920	IKBKB	S1124	T1130N	1130	Missense	distal	6	no	16.612	17.205	EPSD	ICGC;COSMIC	16.613	Gain
Other_IKK_IKBKB_ST	Q9Y4G8	RAPGEF2	O14920	IKBKB	S1166	V1165F	1165	Missense	proximal	-1	no	19.186	19.380	EPSD	ICGC	16.613	Up-regulation
Other_IKK_IKBKB_ST	Q9Y4G8	RAPGEF2	O14920	IKBKB	S1322	S1325I	1325	Missense	distal	3	no	18.220	13.322	EPSD	ICGC	16.613	Loss
Other_IKK_IKBKB_ST	Q9Y4G8	RAPGEF2	O14920	IKBKB	S1322	R1323L	1323	Missense	proximal	1	no	18.220	18.598	EPSD	ICGC	16.613	Up-regulation
Other_IKK_IKBKB_ST	Q9Y4G8	RAPGEF2	O14920	IKBKB	S1325	T1330K	1330	Missense	distal	5	no	16.907	20.161	EPSD	ICGC;COSMIC	16.613	Up-regulation
Other_IKK_IKBKB_ST	Q9Y4G8	RAPGEF2	O14920	IKBKB	S1325	S1325I	1325	Missense	central	0	yes	16.907	0.000	EPSD	ICGC	16.613	Loss
Other_IKK_IKBKB_ST	Q9Y4G8	RAPGEF2	O14920	IKBKB	S1325	R1323L	1323	Missense	proximal	-2	no	16.907	17.903	EPSD	ICGC	16.613	Up-regulation
Other_IKK_IKBKB_ST	Q9Y4G8	RAPGEF2	O14920	IKBKB	S1497	A1498S	1498	Missense	proximal	1	no	16.545	16.972	EPSD	ICGC	16.613	Gain
Other_IKK_IKBKB_ST	P35568	IRS1	O14920	IKBKB	S270	R265H	265	Missense	distal	-5	no	16.872	16.959	EPSD	ICGC	16.613	Up-regulation
Other_IKK_IKBKB_ST	P35568	IRS1	O14920	IKBKB	S270	F264L	264	Missense	distal	-6	no	16.872	17.386	EPSD	ICGC	16.613	Up-regulation
Other_IKK_IKBKB_ST	P35568	IRS1	O14920	IKBKB	S270	S272P	272	Missense	proximal	2	no	16.872	16.615	EPSD	ICGC	16.613	Down-regulation
Other_IKK_IKBKB_ST	P35568	IRS1	O14920	IKBKB	S270	S268I	268	Missense	proximal	-2	no	16.872	17.177	EPSD	ICGC;COSMIC	16.613	Up-regulation
Other_IKK_IKBKB_ST	P35568	IRS1	O14920	IKBKB	S273	N278T	278	Missense	distal	5	no	16.209	16.941	EPSD	ICGC	16.613	Gain
Other_IKK_IKBKB_ST	P35568	IRS1	O14920	IKBKB	S274	S272P	272	Missense	proximal	-2	no	20.210	21.096	EPSD	ICGC	16.613	Up-regulation
Other_IKK_IKBKB_ST	P35568	IRS1	O14920	IKBKB	S274	N278T	278	Missense	distal	4	no	20.210	19.572	EPSD	ICGC	16.613	Down-regulation
Other_IKK_IKBKB_ST	P35568	IRS1	O14920	IKBKB	S274	S268I	268	Missense	distal	-6	no	20.210	18.998	EPSD	ICGC;COSMIC	16.613	Down-regulation
Other_IKK_IKBKB_ST	P35568	IRS1	O14920	IKBKB	S281	H287N	287	Missense	distal	6	no	20.858	21.631	EPSD	ICGC;COSMIC	16.613	Up-regulation
Other_IKK_IKBKB_ST	P35568	IRS1	O14920	IKBKB	S281	N278T	278	Missense	distal	-3	no	20.858	20.560	EPSD	ICGC	16.613	Down-regulation
Other_IKK_IKBKB_ST	P35568	IRS1	O14920	IKBKB	S295	P293L	293	Missense	proximal	-2	no	17.269	17.155	EPSD	ICGC;COSMIC	16.613	Down-regulation
Other_IKK_IKBKB_ST	P35568	IRS1	O14920	IKBKB	S295	P292L	292	Missense	distal	-3	no	17.269	17.408	EPSD	ICGC	16.613	Up-regulation
Other_IKK_IKBKB_ST	P35568	IRS1	O14920	IKBKB	S295	T300P	300	Missense	distal	5	no	17.269	17.791	EPSD	ICGC;COSMIC;GDSC	16.613	Up-regulation
Other_IKK_IKBKB_ST	P35568	IRS1	O14920	IKBKB	S295	V297G	297	Missense	proximal	2	no	17.269	16.351	EPSD	ICGC;COSMIC	16.613	Loss
Other_IKK_IKBKB_ST	P35568	IRS1	O14920	IKBKB	S312	G319R	319	Missense	distal	7	no	24.537	25.022	PhosphoSitePlus	ICGC;COSMIC	16.613	Up-regulation
Other_IKK_IKBKB_ST	P35568	IRS1	O14920	IKBKB	S315	G319R	319	Missense	distal	4	no	15.643	17.979	EPSD	ICGC;COSMIC	16.613	Gain
Other_IKK_IKBKB_ST	P35568	IRS1	O14920	IKBKB	S341	S345N	345	Missense	distal	4	no	18.216	15.349	EPSD	ICGC	16.613	Loss
Other_IKK_IKBKB_ST	P35568	IRS1	O14920	IKBKB	S345	S345N	345	Missense	central	0	yes	16.759	0.000	EPSD	ICGC	16.613	Loss
Other_IKK_IKBKB_ST	P35568	IRS1	O14920	IKBKB	S398	S402C	402	Missense	distal	4	no	23.451	19.570	EPSD	ICGC;COSMIC	16.613	Down-regulation
Other_IKK_IKBKB_ST	P35568	IRS1	O14920	IKBKB	S398	S393T	393	Missense	distal	-5	no	23.451	23.487	EPSD	ICGC;COSMIC	16.613	Up-regulation
Other_IKK_IKBKB_ST	P35568	IRS1	O14920	IKBKB	S398	S396G	396	Missense	proximal	-2	no	23.451	24.164	EPSD	ICGC;CCLE	16.613	Up-regulation
Other_IKK_IKBKB_ST	P35568	IRS1	O14920	IKBKB	S402	S402C	402	Missense	central	0	yes	19.297	0.000	EPSD	ICGC;COSMIC	16.613	Loss
Other_IKK_IKBKB_ST	P35568	IRS1	O14920	IKBKB	S402	S396G	396	Missense	distal	-6	no	19.297	18.600	EPSD	ICGC;CCLE	16.613	Down-regulation
Other_IKK_IKBKB_ST	P35568	IRS1	O14920	IKBKB	S463	R457H	457	Missense	distal	-6	no	25.203	25.750	EPSD	ICGC;COSMIC	16.613	Up-regulation
Other_IKK_IKBKB_ST	P35568	IRS1	O14920	IKBKB	S463	A456D	456	Missense	distal	-7	no	25.203	24.758	EPSD	ICGC;COSMIC	16.613	Down-regulation
Other_IKK_IKBKB_ST	P35568	IRS1	O14920	IKBKB	S531	S531Y	531	Missense	central	0	yes	20.262	0.000	EPSD	ICGC	16.613	Loss
Other_IKK_IKBKB_ST	P35568	IRS1	O14920	IKBKB	S547	P540S	540	Missense	distal	-7	no	16.227	17.500	EPSD	ICGC	16.613	Gain
Other_IKK_IKBKB_ST	P35568	IRS1	O14920	IKBKB	S869	K867T	867	Missense	proximal	-2	no	19.349	19.712	EPSD	ICGC	16.613	Up-regulation
Other_IKK_IKBKB_ST	P35568	IRS1	O14920	IKBKB	S869	R873P	873	Missense	distal	4	no	19.349	19.715	EPSD	ICGC	16.613	Up-regulation
Other_IKK_IKBKB_ST	P35568	IRS1	O14920	IKBKB	S869	P866T	866	Missense	distal	-3	no	19.349	19.976	EPSD	ICGC	16.613	Up-regulation
Other_IKK_IKBKB_ST	P35568	IRS1	O14920	IKBKB	S869	A874G	874	Missense	distal	5	no	19.349	15.722	EPSD	ICGC;COSMIC	16.613	Loss
Other_IKK_IKBKB_ST	P35568	IRS1	O14920	IKBKB	S1000	D1003N	1003	Missense	distal	3	no	18.616	18.713	EPSD	ICGC;COSMIC	16.613	Up-regulation
Other_IKK_IKBKB_ST	P35568	IRS1	O14920	IKBKB	S1037	P1044T	1044	Missense	distal	7	no	17.849	17.956	EPSD	ICGC;COSMIC	16.613	Up-regulation
Other_IKK_IKBKB_ST	P35568	IRS1	O14920	IKBKB	S1043	P1044T	1044	Missense	proximal	1	no	25.354	23.592	EPSD	ICGC;COSMIC	16.613	Down-regulation
Other_IKK_IKBKB_ST	P35568	IRS1	O14920	IKBKB	S1078	A1071T	1071	Missense	distal	-7	no	20.834	20.403	EPSD	ICGC;GDSC;CCLE	16.613	Down-regulation
Other_IKK_IKBKB_ST	P35568	IRS1	O14920	IKBKB	S1105	S1106L	1106	Missense	proximal	1	no	16.307	17.076	EPSD	ICGC;COSMIC	16.613	Gain
Other_IKK_IKBKB_ST	P35568	IRS1	O14920	IKBKB	S1109	S1106L	1106	Missense	distal	-3	no	18.803	18.394	EPSD	ICGC;COSMIC	16.613	Down-regulation
Other_IKK_IKBKB_ST	P35568	IRS1	O14920	IKBKB	S1109	R1112W	1112	Missense	distal	3	no	18.803	14.602	EPSD	ICGC;COSMIC	16.613	Loss
Other_IKK_IKBKB_ST	P35568	IRS1	O14920	IKBKB	S1109	R1112G	1112	Missense	distal	3	no	18.803	18.910	EPSD	ICGC;COSMIC	16.613	Up-regulation
Other_IKK_IKBKB_ST	P35568	IRS1	O14920	IKBKB	S1131	D1137N	1137	Missense	distal	6	no	16.828	17.473	EPSD	ICGC	16.613	Up-regulation
Other_IKK_IKBKB_ST	P35568	IRS1	O14920	IKBKB	S1213	L1211R	1211	Missense	proximal	-2	no	24.941	23.945	EPSD	ICGC;COSMIC	16.613	Down-regulation
Other_IKK_IKBKB_ST	P35568	IRS1	O14920	IKBKB	S1213	R1220H	1220	Missense	distal	7	no	24.941	24.693	EPSD	ICGC;COSMIC	16.613	Down-regulation
Other_IKK_IKBKB_ST	P35568	IRS1	O14920	IKBKB	S1213	P1207L	1207	Missense	distal	-6	no	24.941	24.566	EPSD	ICGC;COSMIC	16.613	Down-regulation
Other_IKK_IKBKB_ST	P35568	IRS1	O14920	IKBKB	S1213	T1219P	1219	Missense	distal	6	no	24.941	25.451	EPSD	ICGC;COSMIC;GDSC	16.613	Up-regulation
Other_IKK_IKBKB_ST	P35568	IRS1	O14920	IKBKB	S1216	L1211R	1211	Missense	distal	-5	no	20.156	20.183	EPSD	ICGC;COSMIC	16.613	Up-regulation
Other_IKK_IKBKB_ST	P35568	IRS1	O14920	IKBKB	S1216	R1220H	1220	Missense	distal	4	no	20.156	19.252	EPSD	ICGC;COSMIC	16.613	Down-regulation
Other_IKK_IKBKB_ST	P35568	IRS1	O14920	IKBKB	S1216	T1219P	1219	Missense	distal	3	no	20.156	19.815	EPSD	ICGC;COSMIC;GDSC	16.613	Down-regulation
Other_IKK_IKBKB_ST	P35568	IRS1	O14920	IKBKB	T1219	R1220H	1220	Missense	proximal	1	no	16.616	17.206	EPSD	ICGC;COSMIC	16.613	Up-regulation
Other_IKK_IKBKB_ST	P35568	IRS1	O14920	IKBKB	T1219	T1219P	1219	Missense	central	0	yes	16.616	0.000	EPSD	ICGC;COSMIC;GDSC	16.613	Loss
Other_IKK_IKBKB_ST	P35568	IRS1	O14920	IKBKB	S1222	R1220H	1220	Missense	proximal	-2	no	28.475	28.993	EPSD	ICGC;COSMIC	16.613	Up-regulation
Other_IKK_IKBKB_ST	P35568	IRS1	O14920	IKBKB	S1222	T1219P	1219	Missense	distal	-3	no	28.475	27.849	EPSD	ICGC;COSMIC;GDSC	16.613	Down-regulation
Other_IKK_IKBKB_ST	P35568	IRS1	O14920	IKBKB	S1223	R1220H	1220	Missense	distal	-3	no	16.694	16.400	EPSD	ICGC;COSMIC	16.613	Loss
Other_IKK_IKBKB_ST	P35568	IRS1	O14920	IKBKB	S1223	T1219P	1219	Missense	distal	-4	no	16.694	16.871	EPSD	ICGC;COSMIC;GDSC	16.613	Up-regulation
Other_IKK_IKBKB_ST	P35568	IRS1	O14920	IKBKB	S1227	R1220H	1220	Missense	distal	-7	no	23.038	21.843	EPSD	ICGC;COSMIC	16.613	Down-regulation
Other_IKK_IKBKB_ST	P35568	IRS1	O14920	IKBKB	S1231	Q1235H	1235	Missense	distal	4	no	27.300	24.402	EPSD	ICGC;COSMIC	16.613	Down-regulation
Other_IKK_IKBKB_ST	Q7Z434	MAVS	O14920	IKBKB	S100	Q93E	93	Missense	distal	-7	no	15.623	17.511	EPSD	ICGC;COSMIC	16.613	Gain
Other_IKK_IKBKB_ST	Q7Z434	MAVS	O14920	IKBKB	S192	A185T	185	Missense	distal	-7	no	23.226	22.795	EPSD	ICGC;COSMIC	16.613	Down-regulation
Other_IKK_IKBKB_ST	Q7Z434	MAVS	O14920	IKBKB	S192	Q198K	198	Missense	distal	6	no	23.226	21.960	EPSD	ICGC;COSMIC	16.613	Down-regulation
Other_IKK_IKBKB_ST	Q7Z434	MAVS	O14920	IKBKB	S192	L187I	187	Missense	distal	-5	no	23.226	22.955	EPSD	ICGC	16.613	Down-regulation
Other_IKK_IKBKB_ST	Q7Z434	MAVS	O14920	IKBKB	S192	A186S	186	Missense	distal	-6	no	23.226	23.183	EPSD	ICGC	16.613	Down-regulation
Other_IKK_IKBKB_ST	Q7Z434	MAVS	O14920	IKBKB	S192	Q196H	196	Missense	distal	4	no	23.226	20.328	EPSD	ICGC;COSMIC	16.613	Down-regulation
Other_IKK_IKBKB_ST	Q7Z434	MAVS	O14920	IKBKB	S217	G219V	219	Missense	proximal	2	no	21.264	22.182	EPSD	ICGC	16.613	Up-regulation
Other_IKK_IKBKB_ST	Q7Z434	MAVS	O14920	IKBKB	S217	R218C	218	Missense	proximal	1	no	21.264	22.002	EPSD	ICGC;COSMIC	16.613	Up-regulation
Other_IKK_IKBKB_ST	Q7Z434	MAVS	O14920	IKBKB	S226	A231T	231	Missense	distal	5	no	16.775	15.738	EPSD	ICGC;COSMIC	16.613	Loss
Other_IKK_IKBKB_ST	Q7Z434	MAVS	O14920	IKBKB	S226	G219V	219	Missense	distal	-7	no	16.775	14.219	EPSD	ICGC	16.613	Loss
Other_IKK_IKBKB_ST	Q7Z434	MAVS	O14920	IKBKB	S253	P259S	259	Missense	distal	6	no	20.346	19.021	EPSD	ICGC;COSMIC	16.613	Down-regulation
Other_IKK_IKBKB_ST	Q7Z434	MAVS	O14920	IKBKB	S253	S255Y	255	Missense	proximal	2	no	20.346	19.603	EPSD	ICGC;COSMIC	16.613	Down-regulation
Other_IKK_IKBKB_ST	Q7Z434	MAVS	O14920	IKBKB	S256	P259S	259	Missense	distal	3	no	21.111	22.447	EPSD	ICGC;COSMIC	16.613	Up-regulation
Other_IKK_IKBKB_ST	Q7Z434	MAVS	O14920	IKBKB	S256	S263Y	263	Missense	distal	7	no	21.111	19.824	EPSD	ICGC;COSMIC	16.613	Down-regulation
Other_IKK_IKBKB_ST	Q7Z434	MAVS	O14920	IKBKB	S256	S255Y	255	Missense	proximal	-1	no	21.111	21.703	EPSD	ICGC;COSMIC	16.613	Up-regulation
Other_IKK_IKBKB_ST	Q7Z434	MAVS	O14920	IKBKB	S263	P259S	259	Missense	distal	-4	no	20.310	23.834	EPSD	ICGC;COSMIC	16.613	Up-regulation
Other_IKK_IKBKB_ST	Q7Z434	MAVS	O14920	IKBKB	S263	S263Y	263	Missense	central	0	yes	20.310	0.000	EPSD	ICGC;COSMIC	16.613	Loss
Other_IKK_IKBKB_ST	Q7Z434	MAVS	O14920	IKBKB	S366	K362E	362	Missense	distal	-4	no	16.936	19.394	EPSD	ICGC	16.613	Up-regulation
Other_IKK_IKBKB_ST	Q7Z434	MAVS	O14920	IKBKB	S416	G415W	415	Missense	proximal	-1	no	25.672	25.936	EPSD	ICGC	16.613	Up-regulation
Other_IKK_IKBKB_ST	Q7Z434	MAVS	O14920	IKBKB	S416	G415V	415	Missense	proximal	-1	no	25.672	25.543	EPSD	ICGC;COSMIC	16.613	Down-regulation
Other_IKK_IKBKB_ST	Q7Z434	MAVS	O14920	IKBKB	S416	E417D	417	Missense	proximal	1	no	25.672	25.105	EPSD	ICGC	16.613	Down-regulation
Other_IKK_IKBKB_ST	Q7Z434	MAVS	O14920	IKBKB	S416	S409F	409	Missense	distal	-7	no	25.672	23.489	EPSD	ICGC;COSMIC	16.613	Down-regulation
Other_IKK_IKBKB_ST	Q16875	PFKFB3	O14920	IKBKB	S269	R274W	274	Missense	distal	5	no	25.228	22.168	PhosphoSitePlus	ICGC;COSMIC	16.613	Down-regulation
Other_IKK_IKBKB_ST	Q16875	PFKFB3	O14920	IKBKB	S280	A281T	281	Missense	proximal	1	no	19.662	19.388	EPSD	ICGC	16.613	Down-regulation
Other_IKK_IKBKB_ST	Q16875	PFKFB3	O14920	IKBKB	S280	R274W	274	Missense	distal	-6	no	19.662	18.182	EPSD	ICGC;COSMIC	16.613	Down-regulation
Other_IKK_IKBKB_ST	Q16875	PFKFB3	O14920	IKBKB	S403	A404S	404	Missense	proximal	1	no	19.952	20.379	EPSD	ICGC	16.613	Up-regulation
Other_IKK_IKBKB_ST	Q16875	PFKFB3	O14920	IKBKB	S446	R443L	443	Missense	distal	-3	no	22.517	21.948	EPSD	ICGC;COSMIC	16.613	Down-regulation
Other_IKK_IKBKB_ST	P20749	BCL3	O14920	IKBKB	S382	A379T	379	Missense	distal	-3	no	16.631	16.579	EPSD	ICGC	16.613	Loss
Other_IKK_IKBKB_ST	P20749	BCL3	O14920	IKBKB	S382	P383R	383	Missense	proximal	1	no	16.631	15.961	EPSD	ICGC	16.613	Loss
Other_IKK_IKBKB_ST	P20749	BCL3	O14920	IKBKB	S382	L389H	389	Missense	distal	7	no	16.631	16.509	EPSD	ICGC	16.613	Loss
Other_IKK_IKBKB_ST	P20749	BCL3	O14920	IKBKB	S386	A379T	379	Missense	distal	-7	no	18.533	18.101	EPSD	ICGC	16.613	Down-regulation
Other_IKK_IKBKB_ST	P20749	BCL3	O14920	IKBKB	S386	P383R	383	Missense	distal	-3	no	18.533	19.240	EPSD	ICGC	16.613	Up-regulation
Other_IKK_IKBKB_ST	P20749	BCL3	O14920	IKBKB	S386	L389H	389	Missense	distal	3	no	18.533	20.264	EPSD	ICGC	16.613	Up-regulation
Other_IKK_IKBKB_ST	P20749	BCL3	O14920	IKBKB	S387	P383R	383	Missense	distal	-4	no	15.881	17.094	EPSD	ICGC	16.613	Gain
Other_IKK_IKBKB_ST	P20749	BCL3	O14920	IKBKB	S402	P403T	403	Missense	proximal	1	no	16.899	15.136	EPSD	ICGC;COSMIC	16.613	Loss
Other_IKK_IKBKB_ST	P20749	BCL3	O14920	IKBKB	S402	P399Q	399	Missense	distal	-3	no	16.899	17.364	EPSD	ICGC;COSMIC	16.613	Up-regulation
Other_IKK_IKBKB_ST	Q96CV9	OPTN	O14920	IKBKB	S162	V161L	161	Missense	proximal	-1	no	22.256	21.842	EPSD	ICGC	16.613	Down-regulation
Other_IKK_IKBKB_ST	Q96CV9	OPTN	O14920	IKBKB	S171	E175K	175	Missense	distal	4	no	18.566	15.707	EPSD	ICGC	16.613	Loss
Other_IKK_IKBKB_ST	Q96CV9	OPTN	O14920	IKBKB	S173	E175K	175	Missense	proximal	2	no	16.933	17.055	EPSD	ICGC	16.613	Up-regulation
Other_IKK_IKBKB_ST	Q96CV9	OPTN	O14920	IKBKB	S191	E194Q	194	Missense	distal	3	no	17.322	14.415	EPSD	ICGC	16.613	Loss
Other_IKK_IKBKB_ST	Q96CV9	OPTN	O14920	IKBKB	S234	E229D	229	Missense	distal	-5	no	20.993	20.987	EPSD	ICGC	16.613	Down-regulation
Other_IKK_IKBKB_ST	Q96CV9	OPTN	O14920	IKBKB	S269	N270I	270	Missense	proximal	1	no	28.400	29.848	EPSD	ICGC;COSMIC	16.613	Up-regulation
Other_IKK_IKBKB_ST	Q96CV9	OPTN	O14920	IKBKB	S269	R271L	271	Missense	proximal	2	no	28.400	28.383	EPSD	ICGC;COSMIC	16.613	Down-regulation
Other_IKK_IKBKB_ST	Q96CV9	OPTN	O14920	IKBKB	S281	S281I	281	Missense	central	0	yes	16.909	0.000	EPSD	ICGC	16.613	Loss
Other_IKK_IKBKB_ST	Q96CV9	OPTN	O14920	IKBKB	S297	E298K	298	Missense	proximal	1	no	23.857	21.583	EPSD	ICGC	16.613	Down-regulation
Other_IKK_IKBKB_ST	Q96CV9	OPTN	O14920	IKBKB	S297	L304I	304	Missense	distal	7	no	23.857	23.427	EPSD	ICGC;COSMIC	16.613	Down-regulation
Other_IKK_IKBKB_ST	Q96CV9	OPTN	O14920	IKBKB	S308	L304I	304	Missense	distal	-4	no	21.406	20.919	EPSD	ICGC;COSMIC	16.613	Down-regulation
Other_IKK_IKBKB_ST	Q96CV9	OPTN	O14920	IKBKB	S308	Q305K	305	Missense	distal	-3	no	21.406	21.917	EPSD	ICGC;COSMIC	16.613	Up-regulation
Other_IKK_IKBKB_ST	Q96CV9	OPTN	O14920	IKBKB	S473	H476R	476	Missense	distal	3	no	19.936	19.814	EPSD	ICGC;COSMIC	16.613	Down-regulation
Other_IKK_IKBKB_ST	Q96CV9	OPTN	O14920	IKBKB	S473	A480E	480	Missense	distal	7	no	19.936	20.367	EPSD	ICGC;COSMIC	16.613	Up-regulation
Other_IKK_IKBKB_ST	Q96CV9	OPTN	O14920	IKBKB	S473	D474Y	474	Missense	proximal	1	no	19.936	21.318	EPSD	ICGC	16.613	Up-regulation
Other_IKK_IKBKB_ST	Q96CV9	OPTN	O14920	IKBKB	S473	E469K	469	Missense	distal	-4	no	19.936	17.478	EPSD	ICGC	16.613	Down-regulation
Other_IKK_IKBKB_ST	Q96CV9	OPTN	O14920	IKBKB	S513	R511S	511	Missense	proximal	-2	no	22.426	22.651	PhosphoSitePlus	ICGC;COSMIC	16.613	Up-regulation
Other_IKK_IKBKB_ST	Q96CV9	OPTN	O14920	IKBKB	S513	R520C	520	Missense	distal	7	no	22.426	21.924	PhosphoSitePlus	ICGC	16.613	Down-regulation
Other_IKK_IKBKB_ST	Q96CV9	OPTN	O14920	IKBKB	S526	A523V	523	Missense	distal	-3	no	17.673	17.214	EPSD	ICGC;COSMIC	16.613	Down-regulation
Other_IKK_IKBKB_ST	Q96CV9	OPTN	O14920	IKBKB	S526	G522V	522	Missense	distal	-4	no	17.673	13.712	EPSD	ICGC	16.613	Loss
Other_IKK_IKBKB_ST	Q96CV9	OPTN	O14920	IKBKB	S526	D529Y	529	Missense	distal	3	no	17.673	16.512	EPSD	ICGC;COSMIC	16.613	Loss
Other_IKK_IKBKB_ST	Q96CV9	OPTN	O14920	IKBKB	S526	R520C	520	Missense	distal	-6	no	17.673	17.144	EPSD	ICGC	16.613	Down-regulation
Other_IKK_IKBKB_ST	O00161	SNAP23	O14920	IKBKB	S95	K97N	97	Missense	proximal	2	no	26.937	26.129	PhosphoSitePlus	ICGC	16.613	Down-regulation
Other_IKK_IKBKB_ST	O00161	SNAP23	O14920	IKBKB	S95	A98S	98	Missense	distal	3	no	26.937	28.380	PhosphoSitePlus	ICGC	16.613	Up-regulation
Other_IKK_IKBKB_ST	O00161	SNAP23	O14920	IKBKB	S95	G96C	96	Missense	proximal	1	no	26.937	26.560	PhosphoSitePlus	ICGC	16.613	Down-regulation
Other_IKK_IKBKB_ST	O00161	SNAP23	O14920	IKBKB	S95	R89S	89	Missense	distal	-6	no	26.937	27.596	PhosphoSitePlus	ICGC	16.613	Up-regulation
Other_IKK_IKBKB_ST	O43524	FOXO3	O14920	IKBKB	S7	P10T	10	Missense	distal	3	no	18.313	18.654	EPSD	ICGC;COSMIC	16.613	Up-regulation
Other_IKK_IKBKB_ST	O43524	FOXO3	O14920	IKBKB	S200	G198C	198	Missense	proximal	-2	no	16.770	16.573	EPSD	ICGC;COSMIC	16.613	Loss
Other_IKK_IKBKB_ST	O43524	FOXO3	O14920	IKBKB	S200	D199N	199	Missense	proximal	-1	no	16.770	16.324	EPSD	ICGC;COSMIC	16.613	Loss
Other_IKK_IKBKB_ST	O43524	FOXO3	O14920	IKBKB	S203	G198C	198	Missense	distal	-5	no	18.773	18.659	EPSD	ICGC;COSMIC	16.613	Down-regulation
Other_IKK_IKBKB_ST	O43524	FOXO3	O14920	IKBKB	S203	D199N	199	Missense	distal	-4	no	18.773	14.971	EPSD	ICGC;COSMIC	16.613	Loss
Other_IKK_IKBKB_ST	O43524	FOXO3	O14920	IKBKB	S280	A273G	273	Missense	distal	-7	no	23.144	22.568	EPSD	ICGC;COSMIC	16.613	Down-regulation
Other_IKK_IKBKB_ST	O43524	FOXO3	O14920	IKBKB	S280	S286T	286	Missense	distal	6	no	23.144	23.958	EPSD	ICGC	16.613	Up-regulation
Other_IKK_IKBKB_ST	O43524	FOXO3	O14920	IKBKB	S280	S286F	286	Missense	distal	6	no	23.144	25.237	EPSD	ICGC	16.613	Up-regulation
Other_IKK_IKBKB_ST	O43524	FOXO3	O14920	IKBKB	S321	A317T	317	Missense	distal	-4	no	17.349	17.790	EPSD	ICGC;COSMIC	16.613	Up-regulation
Other_IKK_IKBKB_ST	O43524	FOXO3	O14920	IKBKB	S344	D339N	339	Missense	distal	-5	no	16.376	16.691	EPSD	ICGC	16.613	Gain
Other_IKK_IKBKB_ST	O43524	FOXO3	O14920	IKBKB	S421	G424S	424	Missense	distal	3	no	15.446	16.681	EPSD	ICGC;COSMIC	16.613	Gain
Other_IKK_IKBKB_ST	O43524	FOXO3	O14920	IKBKB	S425	G424S	424	Missense	proximal	-1	no	21.730	21.341	EPSD	ICGC;COSMIC	16.613	Down-regulation
Other_IKK_IKBKB_ST	O43524	FOXO3	O14920	IKBKB	S425	G420S	420	Missense	distal	-5	no	21.730	21.858	EPSD	ICGC;COSMIC	16.613	Up-regulation
Other_IKK_IKBKB_ST	O43524	FOXO3	O14920	IKBKB	S425	S429Y	429	Missense	distal	4	no	21.730	17.516	EPSD	ICGC;COSMIC	16.613	Down-regulation
Other_IKK_IKBKB_ST	O43524	FOXO3	O14920	IKBKB	S432	S429Y	429	Missense	distal	-3	no	16.803	16.229	EPSD	ICGC;COSMIC	16.613	Loss
Other_IKK_IKBKB_ST	O43524	FOXO3	O14920	IKBKB	S555	R548C	548	Missense	distal	-7	no	18.413	16.596	EPSD	ICGC;COSMIC	16.613	Loss
Other_IKK_IKBKB_ST	O43524	FOXO3	O14920	IKBKB	S644	G637V	637	Missense	distal	-7	no	22.630	20.074	PhosphoSitePlus	ICGC	16.613	Down-regulation
Other_IKK_IKBKB_ST	Q13568	IRF5	O14920	IKBKB	S446	R453L	453	Missense	distal	7	no	28.670	28.543	PhosphoSitePlus	ICGC;COSMIC	16.613	Down-regulation
Other_IKK_IKBKB_ST	Q13568	IRF5	O14920	IKBKB	S446	R453C	453	Missense	distal	7	no	28.670	28.168	PhosphoSitePlus	ICGC;COSMIC	16.613	Down-regulation
CAMK_MAPKAPK_MNK_MKNK1_ST	P23246	SFPQ	Q9BUB5	MKNK1	S8	R3G	3	Missense	distal	-5	no	12.117	12.038	EPSD;PhosphoSitePlus	ICGC	8.316	Down-regulation
CAMK_MAPKAPK_MNK_MKNK1_ST	P23246	SFPQ	Q9BUB5	MKNK1	S8	R3L	3	Missense	distal	-5	no	12.117	12.240	EPSD;PhosphoSitePlus	ICGC;COSMIC	8.316	Up-regulation
CAMK_MAPKAPK_MNK_MKNK1_ST	P23246	SFPQ	Q9BUB5	MKNK1	S8	G13D	13	Missense	distal	5	no	12.117	11.867	EPSD;PhosphoSitePlus	ICGC;COSMIC	8.316	Down-regulation
CAMK_MAPKAPK_MNK_MKNK1_ST	P23246	SFPQ	Q9BUB5	MKNK1	S283	S283F	283	Missense	central	0	yes	14.701	0.000	PhosphoSitePlus;EPSD	ICGC;COSMIC	8.316	Loss
CAMK_MAPKAPK_MNK_MKNK1_ST	P23246	SFPQ	Q9BUB5	MKNK1	S283	L282S	282	Missense	proximal	-1	no	14.701	14.859	PhosphoSitePlus;EPSD	ICGC	8.316	Up-regulation
CAMK_MAPKAPK_MNK_MKNK1_ST	P23246	SFPQ	Q9BUB5	MKNK1	S379	N377S	377	Missense	proximal	-2	no	9.135	9.826	EPSD	ICGC;COSMIC	8.316	Up-regulation
CAMK_MAPKAPK_MNK_MKNK1_ST	P23246	SFPQ	Q9BUB5	MKNK1	S379	N384T	384	Missense	distal	5	no	9.135	8.962	EPSD	ICGC;COSMIC	8.316	Down-regulation
CAMK_MAPKAPK_MNK_MKNK1_ST	P09651	HNRNPA1	Q9BUB5	MKNK1	S91	D94V	94	Missense	distal	3	no	9.416	9.428	EPSD	ICGC;COSMIC	8.316	Up-regulation
CAMK_MAPKAPK_MNK_MKNK1_ST	P09651	HNRNPA1	Q9BUB5	MKNK1	S91	R88I	88	Missense	distal	-3	no	9.416	6.785	EPSD	ICGC;COSMIC	8.316	Loss
CAMK_MAPKAPK_MNK_MKNK1_ST	P09651	HNRNPA1	Q9BUB5	MKNK1	S91	S91C	91	Missense	central	0	yes	9.416	0.000	EPSD	ICGC;COSMIC	8.316	Loss
CAMK_MAPKAPK_MNK_MKNK1_ST	P09651	HNRNPA1	Q9BUB5	MKNK1	S91	R97K	97	Missense	distal	6	no	9.416	9.518	EPSD	ICGC	8.316	Up-regulation
CAMK_MAPKAPK_MNK_MKNK1_ST	P09651	HNRNPA1	Q9BUB5	MKNK1	S91	A89V	89	Missense	proximal	-2	no	9.416	9.505	EPSD	ICGC	8.316	Up-regulation
CAMK_MAPKAPK_MNK_MKNK1_ST	P09651	HNRNPA1	Q9BUB5	MKNK1	S95	D94V	94	Missense	proximal	-1	no	8.867	8.884	EPSD	ICGC;COSMIC	8.316	Up-regulation
CAMK_MAPKAPK_MNK_MKNK1_ST	P09651	HNRNPA1	Q9BUB5	MKNK1	S95	R88I	88	Missense	distal	-7	no	8.867	8.786	EPSD	ICGC;COSMIC	8.316	Down-regulation
CAMK_MAPKAPK_MNK_MKNK1_ST	P09651	HNRNPA1	Q9BUB5	MKNK1	S95	S91C	91	Missense	distal	-4	no	8.867	7.915	EPSD	ICGC;COSMIC	8.316	Loss
CAMK_MAPKAPK_MNK_MKNK1_ST	P09651	HNRNPA1	Q9BUB5	MKNK1	S95	R97K	97	Missense	proximal	2	no	8.867	8.923	EPSD	ICGC	8.316	Up-regulation
CAMK_MAPKAPK_MNK_MKNK1_ST	P09651	HNRNPA1	Q9BUB5	MKNK1	S95	H101N	101	Missense	distal	6	no	8.867	9.928	EPSD	ICGC;COSMIC	8.316	Up-regulation
CAMK_MAPKAPK_MNK_MKNK1_ST	P09651	HNRNPA1	Q9BUB5	MKNK1	S95	A89V	89	Missense	distal	-6	no	8.867	8.865	EPSD	ICGC	8.316	Down-regulation
CAMK_MAPKAPK_MNK_MKNK1_ST	P09651	HNRNPA1	Q9BUB5	MKNK1	S264	G266V	266	Missense	proximal	2	no	8.768	8.831	EPSD	ICGC	8.316	Up-regulation
CAMK_MAPKAPK_MNK_MKNK1_ST	P09651	HNRNPA1	Q9BUB5	MKNK1	S264	G257V	257	Missense	distal	-7	no	8.768	8.714	EPSD	ICGC	8.316	Down-regulation
CAMK_MAPKAPK_MNK_MKNK1_ST	P09651	HNRNPA1	Q9BUB5	MKNK1	S264	G257S	257	Missense	distal	-7	no	8.768	8.952	EPSD	ICGC;COSMIC;CCLE	8.316	Up-regulation
CAMK_MAPKAPK_MNK_MKNK1_ST	P09651	HNRNPA1	Q9BUB5	MKNK1	S264	P258T	258	Missense	distal	-6	no	8.768	8.770	EPSD	ICGC;COSMIC	8.316	Up-regulation
CAMK_MAPKAPK_MNK_MKNK1_ST	O43597	SPRY2	Q9BUB5	MKNK1	S102	P106S	106	Missense	distal	4	no	5.249	8.719	EPSD	ICGC;COSMIC	8.316	Gain
CAMK_MAPKAPK_MNK_MKNK1_ST	O43597	SPRY2	Q9BUB5	MKNK1	S112	R119Q	119	Missense	distal	7	no	14.586	14.595	PhosphoSitePlus;EPSD	ICGC;COSMIC	8.316	Up-regulation
CAMK_MAPKAPK_MNK_MKNK1_ST	O43597	SPRY2	Q9BUB5	MKNK1	S112	P106S	106	Missense	distal	-6	no	14.586	14.600	PhosphoSitePlus;EPSD	ICGC;COSMIC	8.316	Up-regulation
CAMK_MAPKAPK_MNK_MKNK1_ST	O43597	SPRY2	Q9BUB5	MKNK1	S115	R119Q	119	Missense	distal	4	no	8.815	7.376	EPSD	ICGC;COSMIC	8.316	Loss
CAMK_MAPKAPK_MNK_MKNK1_ST	O43597	SPRY2	Q9BUB5	MKNK1	S115	T122M	122	Missense	distal	7	no	8.815	8.874	EPSD	ICGC;COSMIC	8.316	Up-regulation
CAMK_MAPKAPK_MNK_MKNK1_ST	O43597	SPRY2	Q9BUB5	MKNK1	S116	R119Q	119	Missense	distal	3	no	8.371	8.411	EPSD	ICGC;COSMIC	8.316	Up-regulation
CAMK_MAPKAPK_MNK_MKNK1_ST	O43597	SPRY2	Q9BUB5	MKNK1	S116	T122M	122	Missense	distal	6	no	8.371	7.963	EPSD	ICGC;COSMIC	8.316	Loss
CAMK_MAPKAPK_MNK_MKNK1_ST	O43597	SPRY2	Q9BUB5	MKNK1	S121	R119Q	119	Missense	proximal	-2	no	13.724	13.105	EPSD;PhosphoSitePlus	ICGC;COSMIC	8.316	Down-regulation
CAMK_MAPKAPK_MNK_MKNK1_ST	O43597	SPRY2	Q9BUB5	MKNK1	S121	T122M	122	Missense	proximal	1	no	13.724	12.456	EPSD;PhosphoSitePlus	ICGC;COSMIC	8.316	Down-regulation
CAMK_MAPKAPK_MNK_MKNK1_ST	O43597	SPRY2	Q9BUB5	MKNK1	T124	R119Q	119	Missense	distal	-5	no	9.610	9.667	EPSD	ICGC;COSMIC	8.316	Up-regulation
CAMK_MAPKAPK_MNK_MKNK1_ST	O43597	SPRY2	Q9BUB5	MKNK1	T124	T122M	122	Missense	proximal	-2	no	9.610	9.490	EPSD	ICGC;COSMIC	8.316	Down-regulation
CAMK_MAPKAPK_MNK_MKNK1_ST	O43597	SPRY2	Q9BUB5	MKNK1	T305	C301G	301	Missense	distal	-4	no	8.107	8.971	EPSD	ICGC;COSMIC	8.316	Gain
CAMK_MAPKAPK_MNK_MKNK1_ST	P06730	EIF4E	Q9BUB5	MKNK1	S209	R214K	214	Missense	distal	5	no	11.229	11.265	PhosphoSitePlus	ICGC;COSMIC	8.316	Up-regulation
CAMK_MAPKAPK_MNK_MKNK1_ST	P06730	EIF4E	Q9BUB5	MKNK1	T210	R214K	214	Missense	distal	4	no	10.960	9.541	EPSD	ICGC;COSMIC	8.316	Down-regulation
Other_Aur_AurB_ST	P38159	RBMX	Q96GD4	AURKB	S88	G95R	95	Missense	distal	7	no	0.014	0.015	EPSD	ICGC;COSMIC	0.010	Up-regulation
Other_Aur_AurB_ST	P38159	RBMX	Q96GD4	AURKB	S116	G115R	115	Missense	proximal	-1	no	0.004	0.012	EPSD	ICGC;COSMIC	0.010	Gain
Other_Aur_AurB_ST	P38159	RBMX	Q96GD4	AURKB	S228	P226T	226	Missense	proximal	-2	no	0.003	0.010	EPSD	ICGC;COSMIC	0.010	Gain
Other_Aur_AurB_ST	P38159	RBMX	Q96GD4	AURKB	S326	R324P	324	Missense	proximal	-2	no	0.074	-0.001	PhosphoSitePlus	ICGC;COSMIC	0.010	Loss
Other_Aur_AurB_ST	Q9NQS7	INCENP	Q96GD4	AURKB	S72	R66W	66	Missense	distal	-6	no	0.081	0.079	EPSD;PhosphoSitePlus	ICGC;COSMIC	0.010	Down-regulation
Other_Aur_AurB_ST	Q9NQS7	INCENP	Q96GD4	AURKB	S72	R66Q	66	Missense	distal	-6	no	0.081	0.079	EPSD;PhosphoSitePlus	ICGC;COSMIC	0.010	Down-regulation
Other_Aur_AurB_ST	Q9NQS7	INCENP	Q96GD4	AURKB	S103	R102L	102	Missense	proximal	-1	no	0.012	0.005	EPSD	ICGC	0.010	Loss
Other_Aur_AurB_ST	Q9NQS7	INCENP	Q96GD4	AURKB	S103	R100C	100	Missense	distal	-3	no	0.012	0.006	EPSD	ICGC;COSMIC	0.010	Loss
Other_Aur_AurB_ST	Q9NQS7	INCENP	Q96GD4	AURKB	S106	R102L	102	Missense	distal	-4	no	0.012	0.011	EPSD	ICGC	0.010	Down-regulation
Other_Aur_AurB_ST	Q9NQS7	INCENP	Q96GD4	AURKB	S106	R100C	100	Missense	distal	-6	no	0.012	0.010	EPSD	ICGC;COSMIC	0.010	Down-regulation
Other_Aur_AurB_ST	Q9NQS7	INCENP	Q96GD4	AURKB	S306	S302L	302	Missense	distal	-4	no	0.069	0.068	EPSD	ICGC;COSMIC	0.010	Down-regulation
Other_Aur_AurB_ST	Q9NQS7	INCENP	Q96GD4	AURKB	S306	R304W	304	Missense	proximal	-2	no	0.069	-0.001	EPSD	ICGC;COSMIC;GDSC	0.010	Loss
Other_Aur_AurB_ST	Q9NQS7	INCENP	Q96GD4	AURKB	S306	R304Q	304	Missense	proximal	-2	no	0.069	-0.005	EPSD	ICGC;COSMIC	0.010	Loss
Other_Aur_AurB_ST	Q9NQS7	INCENP	Q96GD4	AURKB	S306	R304L	304	Missense	proximal	-2	no	0.069	-0.002	EPSD	ICGC;COSMIC	0.010	Loss
Other_Aur_AurB_ST	Q9NQS7	INCENP	Q96GD4	AURKB	S336	R338M	338	Missense	proximal	2	no	0.078	0.077	EPSD	ICGC	0.010	Down-regulation
Other_Aur_AurB_ST	Q9NQS7	INCENP	Q96GD4	AURKB	T343	R338M	338	Missense	distal	-5	no	0.013	0.011	EPSD	ICGC	0.010	Down-regulation
Other_Aur_AurB_ST	Q9NQS7	INCENP	Q96GD4	AURKB	S426	T424K	424	Missense	proximal	-2	no	0.004	0.012	EPSD	ICGC;COSMIC	0.010	Gain
Other_Aur_AurB_ST	Q14980	NUMA1	Q96GD4	AURKB	S91	E89K	89	Missense	proximal	-2	no	-0.002	0.012	EPSD	ICGC	0.010	Gain
Other_Aur_AurB_ST	Q14980	NUMA1	Q96GD4	AURKB	T99	E94K	94	Missense	distal	-5	no	0.012	0.013	EPSD	ICGC;COSMIC	0.010	Up-regulation
Other_Aur_AurB_ST	Q14980	NUMA1	Q96GD4	AURKB	S633	R631Q	631	Missense	proximal	-2	no	0.073	0.000	EPSD	ICGC;COSMIC	0.010	Loss
Other_Aur_AurB_ST	Q96FF9	CDCA5	Q96GD4	AURKB	S21	R18S	18	Missense	distal	-3	no	0.010	0.003	EPSD	ICGC;COSMIC	0.010	Loss
Other_Aur_AurB_ST	Q96FF9	CDCA5	Q96GD4	AURKB	S21	P20T	20	Missense	proximal	-1	no	0.010	0.011	EPSD	ICGC;COSMIC	0.010	Up-regulation
Other_Aur_AurB_ST	Q96FF9	CDCA5	Q96GD4	AURKB	S33	P38T	38	Missense	distal	5	no	0.077	0.076	PhosphoSitePlus;EPSD	ICGC;COSMIC	0.010	Down-regulation
Other_Aur_AurB_ST	Q96FF9	CDCA5	Q96GD4	AURKB	S83	S83F	83	Missense	central	0	yes	0.072	0.000	EPSD;PhosphoSitePlus	ICGC	0.010	Loss
Other_Aur_AurB_ST	Q96FF9	CDCA5	Q96GD4	AURKB	S164	R163Q	163	Missense	proximal	-1	no	0.078	0.070	EPSD;PhosphoSitePlus	ICGC;COSMIC	0.010	Down-regulation
Other_Aur_AurB_ST	Q96FF9	CDCA5	Q96GD4	AURKB	S164	R162S	162	Missense	proximal	-2	no	0.078	0.005	EPSD;PhosphoSitePlus	ICGC	0.010	Loss
Other_Aur_AurB_ST	Q9H0H5	RACGAP1	Q96GD4	AURKB	T249	R247S	247	Missense	proximal	-2	no	0.081	0.008	EPSD;PhosphoSitePlus	ICGC;COSMIC	0.010	Loss
Other_Aur_AurB_ST	Q9H0H5	RACGAP1	Q96GD4	AURKB	S387	S387C	387	Missense	central	0	yes	0.076	0.000	PhosphoSitePlus;EPSD	ICGC;COSMIC	0.010	Loss
Other_Aur_AurB_ST	Q9H0H5	RACGAP1	Q96GD4	AURKB	S600	R597T	597	Missense	distal	-3	no	0.010	0.003	EPSD	ICGC;COSMIC	0.010	Loss
Other_Aur_AurB_ST	Q9H0H5	RACGAP1	Q96GD4	AURKB	T601	R597T	597	Missense	distal	-4	no	0.070	0.068	EPSD	ICGC;COSMIC	0.010	Down-regulation
Other_Aur_AurB_ST	O14777	NDC80	Q96GD4	AURKB	S44	K42N	42	Missense	proximal	-2	no	0.010	-0.001	EPSD;PhosphoSitePlus	ICGC;COSMIC	0.010	Loss
Other_Aur_AurB_ST	O14777	NDC80	Q96GD4	AURKB	T49	N46K	46	Missense	distal	-3	no	0.010	0.011	PhosphoSitePlus;EPSD	ICGC;COSMIC	0.010	Up-regulation
Other_Aur_AurB_ST	O14777	NDC80	Q96GD4	AURKB	S55	R52K	52	Missense	distal	-3	no	0.017	0.011	EPSD;PhosphoSitePlus	ICGC	0.010	Down-regulation
Other_Aur_AurB_ST	O14777	NDC80	Q96GD4	AURKB	S499	K497R	497	Missense	proximal	-2	no	0.018	0.077	EPSD	ICGC;COSMIC	0.010	Up-regulation
Other_Aur_AurB_ST	Q8NEM2	SHCBP1	Q96GD4	AURKB	S152	C150R	150	Missense	proximal	-2	no	-0.001	0.069	EPSD	ICGC;COSMIC	0.010	Gain
Other_Aur_AurB_ST	Q8NEM2	SHCBP1	Q96GD4	AURKB	S434	S434L	434	Missense	central	0	yes	0.012	0.000	EPSD	ICGC;COSMIC	0.010	Loss
Other_Aur_AurB_ST	Q8NEM2	SHCBP1	Q96GD4	AURKB	S474	T473K	473	Missense	proximal	-1	no	0.071	0.072	EPSD	ICGC	0.010	Up-regulation
Other_Aur_AurB_ST	P06400	RB1	Q96GD4	AURKB	S82	E79K	79	Missense	distal	-3	no	0.011	0.012	EPSD	ICGC;COSMIC	0.010	Up-regulation
Other_Aur_AurB_ST	P06400	RB1	Q96GD4	AURKB	S862	R857H	857	Missense	distal	-5	no	0.019	0.017	EPSD	ICGC;COSMIC;CCLE	0.010	Down-regulation
Other_Aur_AurB_ST	P78527	PRKDC	Q96GD4	AURKB	S245	Q243R	243	Missense	proximal	-2	no	-0.005	0.069	EPSD	ICGC	0.010	Gain
Other_Aur_AurB_ST	P78527	PRKDC	Q96GD4	AURKB	S702	Y701F	701	Missense	proximal	-1	no	0.011	0.010	EPSD	ICGC;COSMIC	0.010	Down-regulation
Other_Aur_AurB_ST	P78527	PRKDC	Q96GD4	AURKB	S893	R891Q	891	Missense	proximal	-2	no	0.073	0.000	EPSD	ICGC	0.010	Loss
Other_Aur_AurB_ST	P78527	PRKDC	Q96GD4	AURKB	T926	Q925K	925	Missense	proximal	-1	no	0.068	0.069	EPSD	ICGC	0.010	Up-regulation
Other_Aur_AurB_ST	P78527	PRKDC	Q96GD4	AURKB	S1203	R1202I	1202	Missense	proximal	-1	no	0.010	0.002	EPSD	ICGC;COSMIC	0.010	Loss
Other_Aur_AurB_ST	P78527	PRKDC	Q96GD4	AURKB	S1790	R1787S	1787	Missense	distal	-3	no	0.077	0.070	EPSD	ICGC	0.010	Down-regulation
Other_Aur_AurB_ST	Q12888	TP53BP1	Q96GD4	AURKB	S118	T117I	117	Missense	proximal	-1	no	0.070	0.069	EPSD	ICGC;COSMIC	0.010	Down-regulation
Other_Aur_AurB_ST	Q12888	TP53BP1	Q96GD4	AURKB	S118	T117K	117	Missense	proximal	-1	no	0.070	0.071	EPSD	ICGC;COSMIC	0.010	Up-regulation
Other_Aur_AurB_ST	Q12888	TP53BP1	Q96GD4	AURKB	S119	T117I	117	Missense	proximal	-2	no	0.011	0.005	EPSD	ICGC;COSMIC	0.010	Loss
Other_Aur_AurB_ST	Q12888	TP53BP1	Q96GD4	AURKB	S119	T117K	117	Missense	proximal	-2	no	0.011	0.019	EPSD	ICGC;COSMIC	0.010	Up-regulation
Other_Aur_AurB_ST	Q12888	TP53BP1	Q96GD4	AURKB	S208	R206W	206	Missense	proximal	-2	no	0.070	0.001	EPSD	ICGC;COSMIC	0.010	Loss
Other_Aur_AurB_ST	Q12888	TP53BP1	Q96GD4	AURKB	S500	S500F	500	Missense	central	0	yes	0.011	0.000	EPSD	ICGC;COSMIC	0.010	Loss
Other_Aur_AurB_ST	Q12888	TP53BP1	Q96GD4	AURKB	S500	K498N	498	Missense	proximal	-2	no	0.011	0.000	EPSD	ICGC;COSMIC	0.010	Loss
Other_Aur_AurB_ST	Q12888	TP53BP1	Q96GD4	AURKB	T543	E541K	541	Missense	proximal	-2	no	-0.001	0.012	EPSD	ICGC	0.010	Gain
Other_Aur_AurB_ST	Q12888	TP53BP1	Q96GD4	AURKB	S635	S635F	635	Missense	central	0	yes	0.011	0.000	EPSD	ICGC;COSMIC	0.010	Loss
Other_Aur_AurB_ST	Q12888	TP53BP1	Q96GD4	AURKB	S635	R634Q	634	Missense	proximal	-1	no	0.011	0.004	EPSD	ICGC;COSMIC	0.010	Loss
Other_Aur_AurB_ST	Q12888	TP53BP1	Q96GD4	AURKB	S818	L816R	816	Missense	proximal	-2	no	-0.001	0.069	EPSD	ICGC;COSMIC	0.010	Gain
Other_Aur_AurB_ST	Q12888	TP53BP1	Q96GD4	AURKB	S834	Q832K	832	Missense	proximal	-2	no	-0.005	0.010	EPSD	ICGC	0.010	Gain
Other_Aur_AurB_ST	Q12888	TP53BP1	Q96GD4	AURKB	S888	S888C	888	Missense	central	0	yes	0.012	0.000	EPSD	ICGC;COSMIC	0.010	Loss
Other_Aur_AurB_ST	Q12888	TP53BP1	Q96GD4	AURKB	S1086	Q1085K	1085	Missense	proximal	-1	no	0.070	0.072	EPSD	ICGC	0.010	Up-regulation
Other_Aur_AurB_ST	Q12888	TP53BP1	Q96GD4	AURKB	T1134	R1132W	1132	Missense	proximal	-2	no	0.067	-0.002	EPSD	ICGC;COSMIC;CCLE	0.010	Loss
Other_Aur_AurB_ST	Q12888	TP53BP1	Q96GD4	AURKB	S1148	E1145K	1145	Missense	distal	-3	no	0.070	0.071	EPSD	ICGC;COSMIC	0.010	Up-regulation
Other_Aur_AurB_ST	Q12888	TP53BP1	Q96GD4	AURKB	S1202	S1202R	1202	Missense	central	0	yes	0.071	0.000	EPSD	ICGC	0.010	Loss
Other_Aur_AurB_ST	Q12888	TP53BP1	Q96GD4	AURKB	T1270	R1267I	1267	Missense	distal	-3	no	0.016	0.009	EPSD	ICGC;COSMIC	0.010	Loss
Other_Aur_AurB_ST	Q12888	TP53BP1	Q96GD4	AURKB	T1285	C1283R	1283	Missense	proximal	-2	no	-0.001	0.069	EPSD	ICGC;COSMIC	0.010	Gain
Other_Aur_AurB_ST	Q12888	TP53BP1	Q96GD4	AURKB	S1310	S1310P	1310	Missense	central	0	yes	0.013	0.000	EPSD	ICGC;COSMIC	0.010	Loss
Other_Aur_AurB_ST	Q12888	TP53BP1	Q96GD4	AURKB	S1320	G1318R	1318	Missense	proximal	-2	no	0.001	0.072	EPSD	ICGC;COSMIC	0.010	Gain
Other_Aur_AurB_ST	Q12888	TP53BP1	Q96GD4	AURKB	S1342	R1338K	1338	Missense	distal	-4	no	0.014	0.013	PhosphoSitePlus	ICGC;COSMIC	0.010	Down-regulation
Other_Aur_AurB_ST	Q12888	TP53BP1	Q96GD4	AURKB	S1342	G1343R	1343	Missense	proximal	1	no	0.014	0.013	PhosphoSitePlus	ICGC	0.010	Down-regulation
Other_Aur_AurB_ST	Q12888	TP53BP1	Q96GD4	AURKB	T1409	R1403H	1403	Missense	distal	-6	no	0.071	0.069	EPSD	ICGC;COSMIC	0.010	Down-regulation
Other_Aur_AurB_ST	Q12888	TP53BP1	Q96GD4	AURKB	T1409	R1407Q	1407	Missense	proximal	-2	no	0.071	-0.003	EPSD	ICGC	0.010	Loss
Other_Aur_AurB_ST	Q12888	TP53BP1	Q96GD4	AURKB	T1414	R1407Q	1407	Missense	distal	-7	no	0.067	0.068	EPSD	ICGC	0.010	Up-regulation
Other_Aur_AurB_ST	Q12888	TP53BP1	Q96GD4	AURKB	S1460	R1458C	1458	Missense	proximal	-2	no	0.079	0.009	EPSD	ICGC;COSMIC	0.010	Loss
Other_Aur_AurB_ST	Q12888	TP53BP1	Q96GD4	AURKB	S1460	R1459H	1459	Missense	proximal	-1	no	0.079	0.072	EPSD	ICGC;COSMIC	0.010	Down-regulation
Other_Aur_AurB_ST	Q12888	TP53BP1	Q96GD4	AURKB	S1496	R1490C	1490	Missense	distal	-6	no	0.014	0.013	EPSD	ICGC;COSMIC	0.010	Down-regulation
Other_Aur_AurB_ST	Q12888	TP53BP1	Q96GD4	AURKB	S1631	R1627L	1627	Missense	distal	-4	no	0.080	0.079	EPSD	ICGC;COSMIC	0.010	Down-regulation
Other_Aur_AurB_ST	Q12888	TP53BP1	Q96GD4	AURKB	S1660	S1665L	1665	Missense	distal	5	no	0.069	0.070	EPSD	ICGC;COSMIC	0.010	Up-regulation
Other_Aur_AurB_ST	Q12888	TP53BP1	Q96GD4	AURKB	S1660	P1657L	1657	Missense	distal	-3	no	0.069	0.070	EPSD	ICGC;COSMIC	0.010	Up-regulation
Other_Aur_AurB_ST	Q12888	TP53BP1	Q96GD4	AURKB	S1678	E1676K	1676	Missense	proximal	-2	no	0.005	0.018	EPSD	ICGC;COSMIC	0.010	Gain
Other_Aur_AurB_ST	Q12888	TP53BP1	Q96GD4	AURKB	S1686	R1684H	1684	Missense	proximal	-2	no	0.074	0.004	EPSD	ICGC;COSMIC	0.010	Loss
Other_Aur_AurB_ST	Q12888	TP53BP1	Q96GD4	AURKB	S1686	R1684C	1684	Missense	proximal	-2	no	0.074	0.004	EPSD	ICGC;COSMIC	0.010	Loss
Other_Aur_AurB_ST	Q12888	TP53BP1	Q96GD4	AURKB	S1749	S1747R	1747	Missense	proximal	-2	no	0.006	0.079	EPSD	ICGC	0.010	Gain
Other_Aur_AurB_ST	Q12888	TP53BP1	Q96GD4	AURKB	S1853	G1851R	1851	Missense	proximal	-2	no	-0.004	0.068	EPSD	ICGC;COSMIC	0.010	Gain
Other_Aur_AurB_ST	Q53HL2	CDCA8	Q96GD4	AURKB	S164	G159R	159	Missense	distal	-5	no	0.016	0.018	EPSD	ICGC;COSMIC	0.010	Up-regulation
Other_Aur_AurB_ST	Q53HL2	CDCA8	Q96GD4	AURKB	S165	G159R	159	Missense	distal	-6	no	0.071	0.072	EPSD;PhosphoSitePlus	ICGC;COSMIC	0.010	Up-regulation
Other_Aur_AurB_ST	Q9NQG5	RPRD1B	Q96GD4	AURKB	S145	R148L	148	Missense	distal	3	no	0.012	0.013	PhosphoSitePlus	ICGC	0.010	Up-regulation
Other_Aur_AurB_ST	Q9NQG5	RPRD1B	Q96GD4	AURKB	T149	R148L	148	Missense	proximal	-1	no	0.020	0.012	EPSD	ICGC	0.010	Down-regulation
Other_Aur_AurB_ST	O00571	DDX3X	Q96GD4	AURKB	S290	R292Q	292	Missense	proximal	2	no	0.017	0.016	EPSD	ICGC;COSMIC	0.010	Down-regulation
Other_Aur_AurB_ST	O00571	DDX3X	Q96GD4	AURKB	S429	R428Q	428	Missense	proximal	-1	no	0.020	0.012	EPSD	ICGC;COSMIC;GDSC;CCLE	0.010	Down-regulation
Other_Aur_AurB_ST	O00571	DDX3X	Q96GD4	AURKB	S588	S584G	584	Missense	distal	-4	no	0.018	0.017	EPSD	ICGC;COSMIC	0.010	Down-regulation
Other_Aur_AurB_ST	Q99661	KIF2C	Q96GD4	AURKB	S109	R113H	113	Missense	distal	4	no	0.011	0.010	EPSD;PhosphoSitePlus	ICGC	0.010	Down-regulation
Other_Aur_AurB_ST	Q99661	KIF2C	Q96GD4	AURKB	S109	R113L	113	Missense	distal	4	no	0.011	0.010	EPSD;PhosphoSitePlus	ICGC	0.010	Down-regulation
Other_Aur_AurB_ST	Q99661	KIF2C	Q96GD4	AURKB	T112	R113H	113	Missense	proximal	1	no	0.067	0.068	EPSD	ICGC	0.010	Up-regulation
Other_Aur_AurB_ST	Q99661	KIF2C	Q96GD4	AURKB	T112	R113L	113	Missense	proximal	1	no	0.067	0.068	EPSD	ICGC	0.010	Up-regulation
Other_Aur_AurB_ST	Q99661	KIF2C	Q96GD4	AURKB	S115	R113H	113	Missense	proximal	-2	no	0.071	0.000	EPSD;PhosphoSitePlus	ICGC	0.010	Loss
Other_Aur_AurB_ST	Q99661	KIF2C	Q96GD4	AURKB	S115	R113L	113	Missense	proximal	-2	no	0.071	0.000	EPSD;PhosphoSitePlus	ICGC	0.010	Loss
Other_Aur_AurB_ST	P14136	GFAP	Q96GD4	AURKB	T7	R12C	12	Missense	distal	5	no	0.076	0.078	EPSD;PhosphoSitePlus	ICGC	0.010	Up-regulation
Other_Aur_AurB_ST	P14136	GFAP	Q96GD4	AURKB	T7	R5L	5	Missense	proximal	-2	no	0.076	0.006	EPSD;PhosphoSitePlus	ICGC	0.010	Loss
Other_Aur_AurB_ST	P14136	GFAP	Q96GD4	AURKB	S13	R12C	12	Missense	proximal	-1	no	0.078	0.071	EPSD;PhosphoSitePlus	ICGC	0.010	Down-regulation
Other_Aur_AurB_ST	P14136	GFAP	Q96GD4	AURKB	S38	R36H	36	Missense	proximal	-2	no	0.070	0.000	PhosphoSitePlus;EPSD	ICGC;COSMIC	0.010	Loss
Other_Aur_AurB_ST	P14136	GFAP	Q96GD4	AURKB	S38	P33T	33	Missense	distal	-5	no	0.070	0.071	PhosphoSitePlus;EPSD	ICGC	0.010	Up-regulation
Other_Aur_AurB_ST	P14136	GFAP	Q96GD4	AURKB	T302	T302M	302	Missense	central	0	yes	0.068	0.000	EPSD	ICGC;COSMIC;GDSC	0.010	Loss
Other_Aur_AurB_ST	Q3KR16	PLEKHG6	Q96GD4	AURKB	S297	R296H	296	Missense	proximal	-1	no	0.026	0.018	EPSD	ICGC;COSMIC	0.010	Down-regulation
Other_Aur_AurB_ST	Q3KR16	PLEKHG6	Q96GD4	AURKB	S537	R535M	535	Missense	proximal	-2	no	0.072	0.001	EPSD	ICGC;COSMIC	0.010	Loss
Other_Aur_AurB_ST	Q3KR16	PLEKHG6	Q96GD4	AURKB	S603	S603P	603	Missense	central	0	yes	0.010	0.000	EPSD	ICGC;COSMIC	0.010	Loss
Other_Aur_AurB_ST	Q3KR16	PLEKHG6	Q96GD4	AURKB	S603	R602L	602	Missense	proximal	-1	no	0.010	0.003	EPSD	ICGC;COSMIC	0.010	Loss
Other_Aur_AurB_ST	Q3KR16	PLEKHG6	Q96GD4	AURKB	T620	R614L	614	Missense	distal	-6	no	0.068	0.066	EPSD;PhosphoSitePlus	ICGC	0.010	Down-regulation
Other_Aur_AurB_ST	Q3KR16	PLEKHG6	Q96GD4	AURKB	S645	R643H	643	Missense	proximal	-2	no	0.078	0.007	EPSD;PhosphoSitePlus	ICGC;COSMIC	0.010	Loss
Other_Aur_AurB_ST	Q96GD4	AURKB	Q96GD4	AURKB	T16	T16K	16	Missense	central	0	yes	0.068	0.000	EPSD;PhosphoSitePlus	ICGC	0.010	Loss
Other_Aur_AurB_ST	P17661	DES	Q96GD4	AURKB	S12	R16H	16	Missense	distal	4	no	0.070	0.069	EPSD;PhosphoSitePlus	ICGC;COSMIC	0.010	Down-regulation
Other_Aur_AurB_ST	P17661	DES	Q96GD4	AURKB	T17	R16H	16	Missense	proximal	-1	no	0.075	0.068	PhosphoSitePlus;EPSD	ICGC;COSMIC	0.010	Down-regulation
Other_Aur_AurB_ST	P17661	DES	Q96GD4	AURKB	S60	R58C	58	Missense	proximal	-2	no	0.075	0.005	EPSD;PhosphoSitePlus	ICGC;COSMIC	0.010	Loss
Other_Aur_AurB_ST	P17661	DES	Q96GD4	AURKB	S60	R58L	58	Missense	proximal	-2	no	0.075	0.004	EPSD;PhosphoSitePlus	ICGC;COSMIC	0.010	Loss
Other_Aur_AurB_ST	P35659	DEK	Q96GD4	AURKB	T67	E64K	64	Missense	distal	-3	no	0.065	0.066	PhosphoSitePlus	ICGC;COSMIC	0.010	Up-regulation
Other_Aur_AurB_ST	P35659	DEK	Q96GD4	AURKB	S204	N209K	209	Missense	distal	5	no	0.016	0.015	EPSD	ICGC	0.010	Down-regulation
Other_Aur_AurB_ST	P35659	DEK	Q96GD4	AURKB	S210	R215K	215	Missense	distal	5	no	0.068	0.070	EPSD	ICGC	0.010	Up-regulation
Other_Aur_AurB_ST	P35659	DEK	Q96GD4	AURKB	S210	N209K	209	Missense	proximal	-1	no	0.068	0.070	EPSD	ICGC	0.010	Up-regulation
Other_Aur_AurB_ST	P35659	DEK	Q96GD4	AURKB	S211	N209K	209	Missense	proximal	-2	no	0.006	0.017	EPSD	ICGC	0.010	Gain
Other_Aur_AurB_ST	P35659	DEK	Q96GD4	AURKB	T220	R215K	215	Missense	distal	-5	no	0.019	0.018	EPSD	ICGC	0.010	Down-regulation
Other_Aur_AurB_ST	P35659	DEK	Q96GD4	AURKB	T220	T220N	220	Missense	central	0	yes	0.019	0.000	EPSD	ICGC	0.010	Loss
Other_Aur_AurB_ST	P35659	DEK	Q96GD4	AURKB	S301	K299I	299	Missense	proximal	-2	no	0.014	0.000	EPSD	ICGC;COSMIC	0.010	Loss
Other_Aur_AurB_ST	P05787	KRT8	Q96GD4	AURKB	T187	R186C	186	Missense	proximal	-1	no	0.015	0.007	EPSD	ICGC;COSMIC	0.010	Loss
Other_Aur_AurB_ST	P05787	KRT8	Q96GD4	AURKB	T187	E190K	190	Missense	distal	3	no	0.015	0.014	EPSD	ICGC	0.010	Down-regulation
Other_Aur_AurB_ST	P05787	KRT8	Q96GD4	AURKB	T303	R301W	301	Missense	proximal	-2	no	0.075	0.005	EPSD	ICGC;COSMIC	0.010	Loss
Other_Aur_AurB_ST	P05787	KRT8	Q96GD4	AURKB	T416	S410G	410	Missense	distal	-6	no	0.010	0.009	EPSD	ICGC;COSMIC	0.010	Loss
Other_Aur_AurB_ST	P04637	TP53	Q96GD4	AURKB	T125	C124R	124	Missense	proximal	-1	no	0.004	0.011	EPSD	ICGC;COSMIC;GDSC;CCLE	0.010	Gain
Other_Aur_AurB_ST	P04637	TP53	Q96GD4	AURKB	S127	T125R	125	Missense	proximal	-2	no	0.005	0.072	EPSD	ICGC;COSMIC	0.010	Gain
Other_Aur_AurB_ST	P04637	TP53	Q96GD4	AURKB	S127	C124R	124	Missense	distal	-3	no	0.005	0.011	EPSD	ICGC;COSMIC;GDSC;CCLE	0.010	Gain
Other_Aur_AurB_ST	P04637	TP53	Q96GD4	AURKB	S183	H178D	178	Missense	distal	-5	no	0.073	0.072	EPSD;PhosphoSitePlus	ICGC;COSMIC;CCLE	0.010	Down-regulation
Other_Aur_AurB_ST	P04637	TP53	Q96GD4	AURKB	S183	D184H	184	Missense	proximal	1	no	0.073	0.072	EPSD;PhosphoSitePlus	ICGC;COSMIC	0.010	Down-regulation
Other_Aur_AurB_ST	P04637	TP53	Q96GD4	AURKB	S183	A189T	189	Missense	distal	6	no	0.073	0.072	EPSD;PhosphoSitePlus	ICGC;COSMIC	0.010	Down-regulation
Other_Aur_AurB_ST	P04637	TP53	Q96GD4	AURKB	S183	A189D	189	Missense	distal	6	no	0.073	0.072	EPSD;PhosphoSitePlus	ICGC;COSMIC	0.010	Down-regulation
Other_Aur_AurB_ST	P04637	TP53	Q96GD4	AURKB	S183	E180D	180	Missense	distal	-3	no	0.073	0.072	EPSD;PhosphoSitePlus	ICGC;COSMIC	0.010	Down-regulation
Other_Aur_AurB_ST	P04637	TP53	Q96GD4	AURKB	T211	T211P	211	Missense	central	0	yes	0.069	0.000	EPSD;PhosphoSitePlus	ICGC;COSMIC	0.010	Loss
Other_Aur_AurB_ST	P04637	TP53	Q96GD4	AURKB	S215	H214D	214	Missense	proximal	-1	no	0.072	0.071	EPSD;PhosphoSitePlus	ICGC;COSMIC	0.010	Down-regulation
Other_Aur_AurB_ST	P04637	TP53	Q96GD4	AURKB	S215	T211P	211	Missense	distal	-4	no	0.072	0.071	EPSD;PhosphoSitePlus	ICGC;COSMIC	0.010	Down-regulation
Other_Aur_AurB_ST	P04637	TP53	Q96GD4	AURKB	S215	F212V	212	Missense	distal	-3	no	0.072	0.071	EPSD;PhosphoSitePlus	ICGC;COSMIC	0.010	Down-regulation
Other_Aur_AurB_ST	P04637	TP53	Q96GD4	AURKB	S269	V274A	274	Missense	distal	5	no	0.071	0.070	EPSD;PhosphoSitePlus	ICGC;COSMIC	0.010	Down-regulation
Other_Aur_AurB_ST	P04637	TP53	Q96GD4	AURKB	S269	V272E	272	Missense	distal	3	no	0.071	0.070	EPSD;PhosphoSitePlus	ICGC;COSMIC;CCLE	0.010	Down-regulation
Other_Aur_AurB_ST	P04637	TP53	Q96GD4	AURKB	S269	N268I	268	Missense	proximal	-1	no	0.071	0.070	EPSD;PhosphoSitePlus	ICGC;COSMIC;GDSC;CCLE	0.010	Down-regulation
Other_Aur_AurB_ST	P04637	TP53	Q96GD4	AURKB	T284	R282P	282	Missense	proximal	-2	no	0.077	0.003	PhosphoSitePlus;EPSD	ICGC;COSMIC	0.010	Loss
Other_Aur_AurB_ST	P04637	TP53	Q96GD4	AURKB	T284	R283S	283	Missense	proximal	-1	no	0.077	0.070	PhosphoSitePlus;EPSD	ICGC;COSMIC	0.010	Down-regulation
Other_Aur_AurB_ST	Q9BQG0	MYBBP1A	Q96GD4	AURKB	S18	T16K	16	Missense	proximal	-2	no	0.006	0.014	EPSD	ICGC	0.010	Gain
Other_Aur_AurB_ST	Q9BQG0	MYBBP1A	Q96GD4	AURKB	S32	F35S	35	Missense	distal	3	no	0.013	0.012	EPSD	ICGC	0.010	Down-regulation
Other_Aur_AurB_ST	Q9BQG0	MYBBP1A	Q96GD4	AURKB	S635	R633S	633	Missense	proximal	-2	no	0.076	0.003	EPSD	ICGC;COSMIC	0.010	Loss
Other_Aur_AurB_ST	Q9BQG0	MYBBP1A	Q96GD4	AURKB	S672	R667H	667	Missense	distal	-5	no	0.013	0.011	EPSD	ICGC	0.010	Down-regulation
Other_Aur_AurB_ST	Q9BQG0	MYBBP1A	Q96GD4	AURKB	S991	N990D	990	Missense	proximal	-1	no	0.074	0.073	EPSD	ICGC;COSMIC	0.010	Down-regulation
Other_Aur_AurB_ST	Q9BQG0	MYBBP1A	Q96GD4	AURKB	S991	R989C	989	Missense	proximal	-2	no	0.074	0.003	EPSD	ICGC;COSMIC	0.010	Loss
Other_Aur_AurB_ST	Q9BQG0	MYBBP1A	Q96GD4	AURKB	S991	S991R	991	Missense	central	0	yes	0.074	0.000	EPSD	ICGC	0.010	Loss
Other_Aur_AurB_ST	Q9BQG0	MYBBP1A	Q96GD4	AURKB	S1186	R1181S	1181	Missense	distal	-5	no	0.075	0.073	EPSD	ICGC	0.010	Down-regulation
Other_Aur_AurB_ST	Q9BQG0	MYBBP1A	Q96GD4	AURKB	T1229	T1227K	1227	Missense	proximal	-2	no	0.002	0.011	EPSD	ICGC	0.010	Gain
Other_Aur_AurB_ST	Q9BQG0	MYBBP1A	Q96GD4	AURKB	S1259	K1257R	1257	Missense	proximal	-2	no	0.013	0.072	EPSD	ICGC;COSMIC;GDSC;CCLE	0.010	Up-regulation
Other_Aur_AurB_ST	Q9BQG0	MYBBP1A	Q96GD4	AURKB	S1259	S1259F	1259	Missense	central	0	yes	0.013	0.000	EPSD	ICGC;COSMIC	0.010	Loss
Other_Aur_AurB_ST	Q9BQG0	MYBBP1A	Q96GD4	AURKB	S1259	Q1260R	1260	Missense	proximal	1	no	0.013	0.012	EPSD	ICGC;COSMIC	0.010	Down-regulation
Other_Aur_AurB_ST	Q9BQG0	MYBBP1A	Q96GD4	AURKB	S1303	S1303F	1303	Missense	central	0	yes	0.073	0.000	PhosphoSitePlus	ICGC;COSMIC;GDSC;CCLE	0.010	Loss
Other_Aur_AurB_ST	Q9BQG0	MYBBP1A	Q96GD4	AURKB	S1308	S1303F	1303	Missense	distal	-5	no	0.010	0.009	EPSD	ICGC;COSMIC;GDSC;CCLE	0.010	Loss
Other_Aur_AurB_ST	Q9UBB4	ATXN10	Q96GD4	AURKB	T41	R37W	37	Missense	distal	-4	no	0.069	0.068	EPSD	ICGC	0.010	Down-regulation
Other_Aur_AurB_ST	Q9UBB4	ATXN10	Q96GD4	AURKB	T41	R39G	39	Missense	proximal	-2	no	0.069	-0.003	EPSD	ICGC	0.010	Loss
Other_Aur_AurB_ST	Q9UBB4	ATXN10	Q96GD4	AURKB	T41	R37Q	37	Missense	distal	-4	no	0.069	0.068	EPSD	ICGC;COSMIC	0.010	Down-regulation
Other_Aur_AurB_ST	Q9H410	DSN1	Q96GD4	AURKB	S95	R93G	93	Missense	proximal	-2	no	0.077	0.005	EPSD	ICGC;COSMIC	0.010	Loss
Other_Aur_AurB_ST	Q9H410	DSN1	Q96GD4	AURKB	S100	A99E	99	Missense	proximal	-1	no	0.079	0.078	EPSD;PhosphoSitePlus	ICGC	0.010	Down-regulation
Other_Aur_AurB_ST	Q9H410	DSN1	Q96GD4	AURKB	S100	R97W	97	Missense	distal	-3	no	0.079	0.072	EPSD;PhosphoSitePlus	ICGC	0.010	Down-regulation
Other_Aur_AurB_ST	O95239	KIF4A	Q96GD4	AURKB	S595	R598L	598	Missense	distal	3	no	0.013	0.014	EPSD	ICGC;COSMIC	0.010	Up-regulation
Other_Aur_AurB_ST	O95239	KIF4A	Q96GD4	AURKB	S595	S595I	595	Missense	central	0	yes	0.013	0.000	EPSD	ICGC;COSMIC	0.010	Loss
Other_Aur_AurB_ST	O95239	KIF4A	Q96GD4	AURKB	S787	E786K	786	Missense	proximal	-1	no	0.016	0.017	EPSD	ICGC	0.010	Up-regulation
Other_Aur_AurB_ST	O95239	KIF4A	Q96GD4	AURKB	T799	R796L	796	Missense	distal	-3	no	0.083	0.076	PhosphoSitePlus	ICGC	0.010	Down-regulation
Other_Aur_AurB_ST	O95239	KIF4A	Q96GD4	AURKB	S801	R796L	796	Missense	distal	-5	no	0.012	0.010	EPSD	ICGC	0.010	Down-regulation
Other_Aur_AurB_ST	Q53SF7	COBLL1	Q96GD4	AURKB	S404	S407R	407	Missense	distal	3	no	0.010	0.009	EPSD	ICGC	0.010	Loss
Other_Aur_AurB_ST	Q8NEY8	PPHLN1	Q96GD4	AURKB	S73	R71Q	71	Missense	proximal	-2	no	0.079	0.005	EPSD	ICGC	0.010	Loss
Other_Aur_AurB_ST	Q8NEY8	PPHLN1	Q96GD4	AURKB	S121	R120Q	120	Missense	proximal	-1	no	0.012	0.004	EPSD	ICGC;COSMIC	0.010	Loss
Other_Aur_AurB_ST	Q8NEY8	PPHLN1	Q96GD4	AURKB	S222	K216R	216	Missense	distal	-6	no	0.009	0.010	EPSD	ICGC	0.010	Gain
Other_Aur_AurB_ST	Q8NEY8	PPHLN1	Q96GD4	AURKB	T396	R400H	400	Missense	distal	4	no	0.076	0.075	EPSD	ICGC;COSMIC	0.010	Down-regulation
Other_Aur_AurB_ST	Q8NEY8	PPHLN1	Q96GD4	AURKB	T403	R400H	400	Missense	distal	-3	no	0.076	0.070	EPSD	ICGC;COSMIC	0.010	Down-regulation
Other_Aur_AurB_ST	Q5UIP0	RIF1	Q96GD4	AURKB	S111	S111P	111	Missense	central	0	yes	0.010	0.000	EPSD	ICGC;COSMIC	0.010	Loss
Other_Aur_AurB_ST	Q5UIP0	RIF1	Q96GD4	AURKB	T409	P407R	407	Missense	proximal	-2	no	-0.004	0.070	EPSD	ICGC;COSMIC	0.010	Gain
Other_Aur_AurB_ST	Q5UIP0	RIF1	Q96GD4	AURKB	T1183	S1180L	1180	Missense	distal	-3	no	0.070	0.069	EPSD	ICGC;COSMIC	0.010	Down-regulation
Other_Aur_AurB_ST	Q5UIP0	RIF1	Q96GD4	AURKB	S1526	D1523Y	1523	Missense	distal	-3	no	0.009	0.010	EPSD	ICGC	0.010	Gain
Other_Aur_AurB_ST	Q5UIP0	RIF1	Q96GD4	AURKB	S1633	Q1631K	1631	Missense	proximal	-2	no	-0.004	0.011	EPSD	ICGC;COSMIC	0.010	Gain
Other_Aur_AurB_ST	Q5UIP0	RIF1	Q96GD4	AURKB	S1723	K1721R	1721	Missense	proximal	-2	no	0.019	0.078	EPSD	ICGC;COSMIC	0.010	Up-regulation
Other_Aur_AurB_ST	Q5UIP0	RIF1	Q96GD4	AURKB	S2205	R2202H	2202	Missense	distal	-3	no	0.077	0.071	PhosphoSitePlus	ICGC;COSMIC	0.010	Down-regulation
Other_Aur_AurB_ST	Q5UIP0	RIF1	Q96GD4	AURKB	S2224	R2221K	2221	Missense	distal	-3	no	0.075	0.070	EPSD	ICGC;COSMIC	0.010	Down-regulation
Other_Aur_AurB_ST	P05204	HMGN2	Q96GD4	AURKB	S25	R23K	23	Missense	proximal	-2	no	0.078	0.019	PhosphoSitePlus;EPSD	ICGC;COSMIC	0.010	Down-regulation
Other_Aur_AurB_ST	P05204	HMGN2	Q96GD4	AURKB	S29	R23K	23	Missense	distal	-6	no	0.077	0.076	EPSD;PhosphoSitePlus	ICGC;COSMIC	0.010	Down-regulation
Other_Aur_AurB_ST	Q08J23	NSUN2	Q96GD4	AURKB	T81	A76V	76	Missense	distal	-5	no	0.069	0.068	EPSD	ICGC	0.010	Down-regulation
Other_Aur_AurB_ST	Q08J23	NSUN2	Q96GD4	AURKB	T552	N547K	547	Missense	distal	-5	no	0.010	0.011	EPSD	ICGC	0.010	Up-regulation
Other_Aur_AurB_ST	O14950	MYL12B	Q96GD4	AURKB	T19	T19A	19	Missense	central	0	yes	0.068	0.000	EPSD	ICGC;COSMIC	0.010	Loss
Other_Aur_AurB_ST	P25490	YY1	Q96GD4	AURKB	S365	F368Y	368	Missense	distal	3	no	0.073	0.072	EPSD	ICGC;COSMIC	0.010	Down-regulation
Other_Aur_AurB_ST	P25490	YY1	Q96GD4	AURKB	S365	G361V	361	Missense	distal	-4	no	0.073	0.072	EPSD	ICGC;COSMIC	0.010	Down-regulation
Other_Aur_AurB_ST	Q8TEW0	PARD3	Q96GD4	AURKB	S715	S715F	715	Missense	central	0	yes	0.081	0.000	EPSD	ICGC	0.010	Loss
Other_Aur_AurB_ST	Q8TEW0	PARD3	Q96GD4	AURKB	S715	R713K	713	Missense	proximal	-2	no	0.081	0.022	EPSD	ICGC	0.010	Down-regulation
Other_Aur_AurB_ST	P53350	PLK1	Q96GD4	AURKB	T366	T366K	366	Missense	central	0	yes	0.064	0.000	EPSD	ICGC;COSMIC	0.010	Loss
Other_Aur_AurB_ST	P53350	PLK1	Q96GD4	AURKB	S565	R563H	563	Missense	proximal	-2	no	0.075	0.005	EPSD	ICGC;COSMIC	0.010	Loss
Other_Aur_AurB_ST	P53350	PLK1	Q96GD4	AURKB	S565	R563C	563	Missense	proximal	-2	no	0.075	0.005	EPSD	ICGC;COSMIC	0.010	Loss
Other_Aur_AurB_ST	P53350	PLK1	Q96GD4	AURKB	S565	R560C	560	Missense	distal	-5	no	0.075	0.073	EPSD	ICGC	0.010	Down-regulation
Other_Aur_AurB_ST	P53350	PLK1	Q96GD4	AURKB	S565	S565I	565	Missense	central	0	yes	0.075	0.000	EPSD	ICGC;COSMIC	0.010	Loss
Other_Aur_AurB_ST	P18615	NELFE	Q96GD4	AURKB	S249	R247Q	247	Missense	proximal	-2	no	0.075	0.001	EPSD	ICGC;COSMIC	0.010	Loss
Other_Aur_AurB_ST	O95235	KIF20A	Q96GD4	AURKB	S226	K224N	224	Missense	proximal	-2	no	0.013	0.002	EPSD	ICGC;COSMIC	0.010	Loss
Other_Aur_AurB_ST	O95235	KIF20A	Q96GD4	AURKB	S226	S226P	226	Missense	central	0	yes	0.013	0.000	EPSD	ICGC	0.010	Loss
Other_Aur_AurB_ST	O95235	KIF20A	Q96GD4	AURKB	S478	C479F	479	Missense	proximal	1	no	0.011	0.012	EPSD	ICGC;COSMIC	0.010	Up-regulation
Other_Aur_AurB_ST	O95235	KIF20A	Q96GD4	AURKB	S677	R675W	675	Missense	proximal	-2	no	0.078	0.009	EPSD	ICGC;COSMIC;GDSC	0.010	Loss
Other_Aur_AurB_ST	O95235	KIF20A	Q96GD4	AURKB	S878	R876L	876	Missense	proximal	-2	no	0.080	0.009	PhosphoSitePlus	ICGC;COSMIC	0.010	Loss
Other_Aur_AurB_ST	Q9Y2I6	NINL	Q96GD4	AURKB	S448	R444W	444	Missense	distal	-4	no	0.072	0.071	EPSD;PhosphoSitePlus	ICGC;COSMIC	0.010	Down-regulation
Other_Aur_AurB_ST	Q9Y2I6	NINL	Q96GD4	AURKB	S585	H584Y	584	Missense	proximal	-1	no	0.068	0.067	PhosphoSitePlus;EPSD	ICGC	0.010	Down-regulation
Other_Aur_AurB_ST	Q9Y2I6	NINL	Q96GD4	AURKB	S585	W588R	588	Missense	distal	3	no	0.068	0.067	PhosphoSitePlus;EPSD	ICGC	0.010	Down-regulation
Other_Aur_AurB_ST	Q9Y2I6	NINL	Q96GD4	AURKB	S585	R583Q	583	Missense	proximal	-2	no	0.068	-0.006	PhosphoSitePlus;EPSD	ICGC;COSMIC	0.010	Loss
Other_Aur_AurB_ST	Q9Y2I6	NINL	Q96GD4	AURKB	S585	S585C	585	Missense	central	0	yes	0.068	0.000	PhosphoSitePlus;EPSD	ICGC;COSMIC	0.010	Loss
Other_Aur_AurB_ST	Q8WWK9	CKAP2	Q96GD4	AURKB	T39	R37K	37	Missense	proximal	-2	no	0.079	0.020	EPSD;PhosphoSitePlus	ICGC	0.010	Down-regulation
Other_Aur_AurB_ST	Q8WWK9	CKAP2	Q96GD4	AURKB	S628	R626C	626	Missense	proximal	-2	no	0.079	0.008	PhosphoSitePlus;EPSD	ICGC;COSMIC	0.010	Loss
Other_Aur_AurB_ST	Q9H6F5	CCDC86	Q96GD4	AURKB	S8	R7C	7	Missense	proximal	-1	no	0.079	0.072	EPSD	ICGC	0.010	Down-regulation
Other_Aur_AurB_ST	Q9H6F5	CCDC86	Q96GD4	AURKB	S66	R71H	71	Missense	distal	5	no	0.010	0.012	EPSD	ICGC;COSMIC	0.010	Up-regulation
Other_Aur_AurB_ST	Q9H6F5	CCDC86	Q96GD4	AURKB	S121	R115Q	115	Missense	distal	-6	no	0.013	0.012	EPSD	ICGC;COSMIC	0.010	Down-regulation
Other_Aur_AurB_ST	Q9H6F5	CCDC86	Q96GD4	AURKB	S128	E123K	123	Missense	distal	-5	no	0.012	0.013	EPSD	ICGC;COSMIC	0.010	Up-regulation
Other_Aur_AurB_ST	Q9H6F5	CCDC86	Q96GD4	AURKB	S128	S128F	128	Missense	central	0	yes	0.012	0.000	EPSD	ICGC	0.010	Loss
Other_Aur_AurB_ST	Q9H6F5	CCDC86	Q96GD4	AURKB	S266	R264H	264	Missense	proximal	-2	no	0.070	-0.001	EPSD	ICGC;COSMIC	0.010	Loss
Other_Aur_AurB_ST	P06748	NPM1	Q96GD4	AURKB	S70	E68K	68	Missense	proximal	-2	no	0.000	0.013	EPSD	ICGC;COSMIC	0.010	Gain
Other_Aur_AurB_ST	P06748	NPM1	Q96GD4	AURKB	S143	R142W	142	Missense	proximal	-1	no	0.020	0.013	EPSD	ICGC	0.010	Down-regulation
Other_Aur_AurB_ST	P06748	NPM1	Q96GD4	AURKB	T199	R197G	197	Missense	proximal	-2	no	0.070	-0.002	EPSD	ICGC;COSMIC	0.010	Loss
Other_Aur_AurB_ST	Q13315	ATM	Q96GD4	AURKB	S333	S333F	333	Missense	central	0	yes	0.014	0.000	EPSD	ICGC;COSMIC	0.010	Loss
Other_Aur_AurB_ST	Q13315	ATM	Q96GD4	AURKB	S363	N358I	358	Missense	distal	-5	no	0.010	0.009	EPSD	ICGC;COSMIC	0.010	Loss
Other_Aur_AurB_ST	Q13315	ATM	Q96GD4	AURKB	S363	S367F	367	Missense	distal	4	no	0.010	0.009	EPSD	ICGC;COSMIC	0.010	Loss
Other_Aur_AurB_ST	Q13315	ATM	Q96GD4	AURKB	S535	G529R	529	Missense	distal	-6	no	0.070	0.072	EPSD	ICGC;COSMIC	0.010	Up-regulation
Other_Aur_AurB_ST	Q13315	ATM	Q96GD4	AURKB	S1881	Q1879K	1879	Missense	proximal	-2	no	-0.002	0.013	EPSD	ICGC;COSMIC	0.010	Gain
Other_Aur_AurB_ST	Q13315	ATM	Q96GD4	AURKB	S2812	S2812F	2812	Missense	central	0	yes	0.010	0.000	EPSD	ICGC	0.010	Loss
Other_Aur_AurB_ST	P46778	RPL21	Q96GD4	AURKB	S104	R102Q	102	Missense	proximal	-2	no	0.072	-0.002	PhosphoSitePlus	ICGC;COSMIC	0.010	Loss
Other_Aur_AurB_ST	P08670	VIM	Q96GD4	AURKB	S25	P24L	24	Missense	proximal	-1	no	0.066	0.067	EPSD	ICGC;COSMIC	0.010	Up-regulation
Other_Aur_AurB_ST	P08670	VIM	Q96GD4	AURKB	S39	R36S	36	Missense	distal	-3	no	0.013	0.006	EPSD	ICGC;COSMIC	0.010	Loss
Other_Aur_AurB_ST	P08670	VIM	Q96GD4	AURKB	S47	R45H	45	Missense	proximal	-2	no	0.069	-0.001	EPSD	ICGC	0.010	Loss
Other_Aur_AurB_ST	P08670	VIM	Q96GD4	AURKB	S66	A62V	62	Missense	distal	-4	no	0.068	0.067	EPSD	ICGC	0.010	Down-regulation
Other_Aur_AurB_ST	Q69YH5	CDCA2	Q96GD4	AURKB	S205	R201C	201	Missense	distal	-4	no	0.077	0.076	EPSD	ICGC;COSMIC	0.010	Down-regulation
Other_Aur_AurB_ST	Q69YH5	CDCA2	Q96GD4	AURKB	S833	R832C	832	Missense	proximal	-1	no	0.086	0.079	EPSD	ICGC;COSMIC	0.010	Down-regulation
Other_Aur_AurB_ST	Q69YH5	CDCA2	Q96GD4	AURKB	S886	R884S	884	Missense	proximal	-2	no	0.076	0.003	EPSD	ICGC;COSMIC	0.010	Loss
Other_Aur_AurB_ST	Q69YH5	CDCA2	Q96GD4	AURKB	S893	R892C	892	Missense	proximal	-1	no	0.076	0.069	PhosphoSitePlus	ICGC;COSMIC	0.010	Down-regulation
Other_Aur_AurB_ST	Q69YH5	CDCA2	Q96GD4	AURKB	S977	R975G	975	Missense	proximal	-2	no	0.078	0.006	EPSD	ICGC;COSMIC	0.010	Loss
Other_Aur_AurB_ST	Q69YH5	CDCA2	Q96GD4	AURKB	S977	S977R	977	Missense	central	0	yes	0.078	0.000	EPSD	ICGC;COSMIC	0.010	Loss
Other_Aur_AurB_ST	Q96CF2	CHMP4C	Q96GD4	AURKB	S210	R208L	208	Missense	proximal	-2	no	0.080	0.009	EPSD;PhosphoSitePlus	ICGC	0.010	Loss
Other_Aur_AurB_ST	Q96CF2	CHMP4C	Q96GD4	AURKB	S210	R208H	208	Missense	proximal	-2	no	0.080	0.009	EPSD;PhosphoSitePlus	ICGC	0.010	Loss
Other_Aur_AurB_ST	Q96CF2	CHMP4C	Q96GD4	AURKB	S210	S205F	205	Missense	distal	-5	no	0.080	0.079	EPSD;PhosphoSitePlus	ICGC	0.010	Down-regulation
Other_Aur_AurB_ST	Q96CF2	CHMP4C	Q96GD4	AURKB	S214	R208L	208	Missense	distal	-6	no	0.013	0.012	EPSD;PhosphoSitePlus	ICGC	0.010	Down-regulation
Other_Aur_AurB_ST	Q96CF2	CHMP4C	Q96GD4	AURKB	S214	R208H	208	Missense	distal	-6	no	0.013	0.012	EPSD;PhosphoSitePlus	ICGC	0.010	Down-regulation
Other_Aur_AurB_ST	P46783	RPS10	Q96GD4	AURKB	T118	R116S	116	Missense	proximal	-2	no	0.069	-0.004	PhosphoSitePlus	ICGC;COSMIC	0.010	Loss
Other_Aur_AurB_ST	Q9Y2R4	DDX52	Q96GD4	AURKB	S258	K256E	256	Missense	proximal	-2	no	0.012	-0.001	EPSD	ICGC	0.010	Loss
Other_Aur_AurB_ST	Q9Y2R4	DDX52	Q96GD4	AURKB	S589	Q587R	587	Missense	proximal	-2	no	-0.004	0.070	EPSD	ICGC	0.010	Gain
Other_Aur_AurB_ST	P82970	HMGN5	Q96GD4	AURKB	S20	S20Y	20	Missense	central	0	yes	0.081	0.000	EPSD;PhosphoSitePlus	ICGC;COSMIC	0.010	Loss
Other_Aur_AurB_ST	P82970	HMGN5	Q96GD4	AURKB	S93	P91R	91	Missense	proximal	-2	no	-0.003	0.072	EPSD	ICGC;COSMIC	0.010	Gain
Other_Aur_AurB_ST	Q96PK6	RBM14	Q96GD4	AURKB	S220	R214L	214	Missense	distal	-6	no	0.083	0.081	EPSD	ICGC;COSMIC	0.010	Down-regulation
Other_Aur_AurB_ST	Q96PK6	RBM14	Q96GD4	AURKB	S220	R218H	218	Missense	proximal	-2	no	0.083	0.012	EPSD	ICGC	0.010	Down-regulation
Other_Aur_AurB_ST	Q96PK6	RBM14	Q96GD4	AURKB	S225	S225C	225	Missense	central	0	yes	0.073	0.000	EPSD	ICGC;COSMIC	0.010	Loss
Other_Aur_AurB_ST	Q96PK6	RBM14	Q96GD4	AURKB	S225	R223G	223	Missense	proximal	-2	no	0.073	0.001	EPSD	ICGC	0.010	Loss
Other_Aur_AurB_ST	Q96PK6	RBM14	Q96GD4	AURKB	S649	R647H	647	Missense	proximal	-2	no	0.070	-0.001	EPSD;PhosphoSitePlus	ICGC;COSMIC;CCLE	0.010	Loss
Other_Aur_AurB_ST	Q5T5U3	ARHGAP21	Q96GD4	AURKB	T1133	K1137R	1137	Missense	distal	4	no	0.067	0.068	EPSD	ICGC;COSMIC	0.010	Up-regulation
Other_Aur_AurB_ST	Q5T5U3	ARHGAP21	Q96GD4	AURKB	T1139	K1137R	1137	Missense	proximal	-2	no	0.013	0.072	EPSD	ICGC;COSMIC	0.010	Up-regulation
Other_Aur_AurB_ST	Q5T5U3	ARHGAP21	Q96GD4	AURKB	S1796	R1799Q	1799	Missense	distal	3	no	0.075	0.076	EPSD	ICGC	0.010	Up-regulation
Other_Aur_AurB_ST	Q5T5U3	ARHGAP21	Q96GD4	AURKB	T1802	R1799Q	1799	Missense	distal	-3	no	0.075	0.068	EPSD	ICGC	0.010	Down-regulation
Other_Aur_AurB_ST	P45973	CBX5	Q96GD4	AURKB	T5	K6M	6	Missense	proximal	1	no	0.009	0.010	EPSD	ICGC;COSMIC	0.010	Gain
Other_Aur_AurB_ST	P45973	CBX5	Q96GD4	AURKB	T8	T8I	8	Missense	central	0	yes	0.016	0.000	EPSD	ICGC;COSMIC	0.010	Loss
Other_Aur_AurB_ST	P45973	CBX5	Q96GD4	AURKB	T8	K6M	6	Missense	proximal	-2	no	0.016	0.004	EPSD	ICGC;COSMIC	0.010	Loss
Other_Aur_AurB_ST	Q8IVT2	MISP	Q96GD4	AURKB	S155	R153K	153	Missense	proximal	-2	no	0.069	0.010	EPSD	ICGC	0.010	Down-regulation
Other_Aur_AurB_ST	Q8IVT2	MISP	Q96GD4	AURKB	S156	S156G	156	Missense	central	0	yes	0.020	0.000	EPSD	ICGC;COSMIC	0.010	Loss
Other_Aur_AurB_ST	Q8IVT2	MISP	Q96GD4	AURKB	S156	R153K	153	Missense	distal	-3	no	0.020	0.015	EPSD	ICGC	0.010	Down-regulation
Other_Aur_AurB_ST	Q8IVT2	MISP	Q96GD4	AURKB	T179	R177L	177	Missense	proximal	-2	no	0.068	-0.003	EPSD	ICGC	0.010	Loss
Other_Aur_AurB_ST	Q8IVT2	MISP	Q96GD4	AURKB	S348	P347L	347	Missense	proximal	-1	no	0.069	0.070	PhosphoSitePlus	ICGC	0.010	Up-regulation
Other_Aur_AurB_ST	Q8IVT2	MISP	Q96GD4	AURKB	S376	T377R	377	Missense	proximal	1	no	0.074	0.073	EPSD	ICGC;COSMIC;GDSC	0.010	Down-regulation
Other_Aur_AurB_ST	Q8IVT2	MISP	Q96GD4	AURKB	T464	S460L	460	Missense	distal	-4	no	0.012	0.011	EPSD	ICGC	0.010	Down-regulation
Other_Aur_AurB_ST	Q8IVT2	MISP	Q96GD4	AURKB	S553	R556L	556	Missense	distal	3	no	0.075	0.076	EPSD	ICGC	0.010	Up-regulation
Other_Aur_AurB_ST	Q8IVT2	MISP	Q96GD4	AURKB	S553	R557L	557	Missense	distal	4	no	0.075	0.074	EPSD	ICGC;COSMIC	0.010	Down-regulation
Other_Aur_AurB_ST	P08238	HSP90AB1	Q96GD4	AURKB	S206	S206F	206	Missense	central	0	yes	0.014	0.000	EPSD	ICGC	0.010	Loss
Other_Aur_AurB_ST	P08238	HSP90AB1	Q96GD4	AURKB	T579	L584R	584	Missense	distal	5	no	0.010	0.008	EPSD	ICGC	0.010	Loss
Other_Aur_AurB_ST	P08238	HSP90AB1	Q96GD4	AURKB	S586	L584R	584	Missense	proximal	-2	no	0.004	0.074	EPSD	ICGC	0.010	Gain
Other_Aur_AurB_ST	Q9H211	CDT1	Q96GD4	AURKB	T102	Q96K	96	Missense	distal	-6	no	0.011	0.012	PhosphoSitePlus;EPSD	ICGC;COSMIC	0.010	Up-regulation
Other_Aur_AurB_ST	Q9H211	CDT1	Q96GD4	AURKB	S463	R459S	459	Missense	distal	-4	no	0.011	0.010	EPSD	ICGC;COSMIC	0.010	Down-regulation
Other_Aur_AurB_ST	Q9UJ70	NAGK	Q96GD4	AURKB	S15	R14Q	14	Missense	proximal	-1	no	0.012	0.004	EPSD	ICGC;COSMIC	0.010	Loss
Other_Aur_AurB_ST	Q8WWI1	LMO7	Q96GD4	AURKB	S90	R88G	88	Missense	proximal	-2	no	0.069	-0.003	EPSD	ICGC;COSMIC	0.010	Loss
Other_Aur_AurB_ST	Q8WWI1	LMO7	Q96GD4	AURKB	S90	R88L	88	Missense	proximal	-2	no	0.069	-0.001	EPSD	ICGC;COSMIC	0.010	Loss
Other_Aur_AurB_ST	Q8WWI1	LMO7	Q96GD4	AURKB	S116	N113D	113	Missense	distal	-3	no	0.072	0.071	EPSD	ICGC;COSMIC	0.010	Down-regulation
Other_Aur_AurB_ST	Q8WWI1	LMO7	Q96GD4	AURKB	S217	S212R	212	Missense	distal	-5	no	0.017	0.019	EPSD	ICGC;COSMIC	0.010	Up-regulation
Other_Aur_AurB_ST	Q8WWI1	LMO7	Q96GD4	AURKB	S342	R340I	340	Missense	proximal	-2	no	0.078	0.006	EPSD	ICGC;COSMIC	0.010	Loss
Other_Aur_AurB_ST	Q8WWI1	LMO7	Q96GD4	AURKB	S345	R340I	340	Missense	distal	-5	no	0.011	0.009	EPSD	ICGC;COSMIC	0.010	Loss
Other_Aur_AurB_ST	Q8WWI1	LMO7	Q96GD4	AURKB	S407	K405N	405	Missense	proximal	-2	no	0.020	0.008	EPSD	ICGC	0.010	Loss
Other_Aur_AurB_ST	Q8WWI1	LMO7	Q96GD4	AURKB	S407	R404C	404	Missense	distal	-3	no	0.020	0.013	EPSD	ICGC	0.010	Down-regulation
Other_Aur_AurB_ST	Q8WWI1	LMO7	Q96GD4	AURKB	S751	R749Q	749	Missense	proximal	-2	no	0.078	0.004	EPSD;PhosphoSitePlus	ICGC	0.010	Loss
Other_Aur_AurB_ST	Q8WWI1	LMO7	Q96GD4	AURKB	S751	R748K	748	Missense	distal	-3	no	0.078	0.072	EPSD;PhosphoSitePlus	ICGC;COSMIC	0.010	Down-regulation
Other_Aur_AurB_ST	Q8WWI1	LMO7	Q96GD4	AURKB	S847	E845K	845	Missense	proximal	-2	no	-0.002	0.011	EPSD	ICGC	0.010	Gain
Other_Aur_AurB_ST	Q8WWI1	LMO7	Q96GD4	AURKB	S884	R891C	891	Missense	distal	7	no	0.012	0.011	EPSD	ICGC	0.010	Down-regulation
Other_Aur_AurB_ST	Q8WWI1	LMO7	Q96GD4	AURKB	S893	R891C	891	Missense	proximal	-2	no	0.066	-0.004	EPSD	ICGC	0.010	Loss
Other_Aur_AurB_ST	Q8WWI1	LMO7	Q96GD4	AURKB	S893	V892F	892	Missense	proximal	-1	no	0.066	0.067	EPSD	ICGC	0.010	Up-regulation
Other_Aur_AurB_ST	Q8WWI1	LMO7	Q96GD4	AURKB	S893	P897S	897	Missense	distal	4	no	0.066	0.067	EPSD	ICGC	0.010	Up-regulation
Other_Aur_AurB_ST	Q8WWI1	LMO7	Q96GD4	AURKB	T949	R948W	948	Missense	proximal	-1	no	0.016	0.008	EPSD	ICGC	0.010	Loss
Other_Aur_AurB_ST	Q8IX03	WWC1	Q96GD4	AURKB	S33	R38Q	38	Missense	distal	5	no	0.009	0.010	EPSD	ICGC;COSMIC	0.010	Gain
Other_Aur_AurB_ST	Q8IX03	WWC1	Q96GD4	AURKB	S255	R250C	250	Missense	distal	-5	no	0.071	0.069	EPSD	ICGC;COSMIC	0.010	Down-regulation
Other_Aur_AurB_ST	Q8IX03	WWC1	Q96GD4	AURKB	S255	S255Y	255	Missense	central	0	yes	0.071	0.000	EPSD	ICGC;COSMIC	0.010	Loss
Other_Aur_AurB_ST	Q8IX03	WWC1	Q96GD4	AURKB	S539	S539P	539	Missense	central	0	yes	0.069	0.000	PhosphoSitePlus	ICGC;COSMIC	0.010	Loss
Other_Aur_AurB_ST	Q8IX03	WWC1	Q96GD4	AURKB	S793	K791R	791	Missense	proximal	-2	no	0.012	0.071	EPSD	ICGC	0.010	Up-regulation
Other_Aur_AurB_ST	Q8IX03	WWC1	Q96GD4	AURKB	S962	S962F	962	Missense	central	0	yes	0.069	0.000	EPSD	ICGC	0.010	Loss
Other_Aur_AurB_ST	Q8IX03	WWC1	Q96GD4	AURKB	S974	S975L	975	Missense	proximal	1	no	0.069	0.070	EPSD	ICGC;COSMIC	0.010	Up-regulation
Other_Aur_AurB_ST	Q8IX03	WWC1	Q96GD4	AURKB	S974	P973L	973	Missense	proximal	-1	no	0.069	0.070	EPSD	ICGC;COSMIC	0.010	Up-regulation
Other_Aur_AurB_ST	Q8IX03	WWC1	Q96GD4	AURKB	S974	P973S	973	Missense	proximal	-1	no	0.069	0.070	EPSD	ICGC;COSMIC	0.010	Up-regulation
Other_Aur_AurB_ST	Q9Y5B9	SUPT16H	Q96GD4	AURKB	S128	G135A	135	Missense	distal	7	no	0.010	0.011	EPSD	ICGC;COSMIC	0.010	Up-regulation
Other_Aur_AurB_ST	Q9Y5B9	SUPT16H	Q96GD4	AURKB	S455	R456Q	456	Missense	proximal	1	no	0.068	0.069	EPSD	ICGC	0.010	Up-regulation
Other_Aur_AurB_ST	Q9Y5B9	SUPT16H	Q96GD4	AURKB	S1023	R1018W	1018	Missense	distal	-5	no	0.020	0.018	EPSD	ICGC	0.010	Down-regulation
Other_Aur_AurB_ST	Q9Y5B9	SUPT16H	Q96GD4	AURKB	S1031	R1033C	1033	Missense	proximal	2	no	0.071	0.070	EPSD	ICGC;COSMIC	0.010	Down-regulation
Other_Aur_AurB_ST	Q9Y5B9	SUPT16H	Q96GD4	AURKB	S1038	R1033C	1033	Missense	distal	-5	no	0.069	0.067	EPSD	ICGC;COSMIC	0.010	Down-regulation
Other_Aur_AurB_ST	Q92538	GBF1	Q96GD4	AURKB	S233	P237R	237	Missense	distal	4	no	0.019	0.020	EPSD	ICGC;COSMIC	0.010	Up-regulation
Other_Aur_AurB_ST	Q92538	GBF1	Q96GD4	AURKB	T301	Q299K	299	Missense	proximal	-2	no	-0.004	0.011	EPSD	ICGC;COSMIC	0.010	Gain
Other_Aur_AurB_ST	Q92538	GBF1	Q96GD4	AURKB	S612	R610G	610	Missense	proximal	-2	no	0.073	0.001	EPSD	ICGC;COSMIC	0.010	Loss
Other_Aur_AurB_ST	Q92538	GBF1	Q96GD4	AURKB	S684	R678Q	678	Missense	distal	-6	no	0.074	0.073	EPSD	ICGC;COSMIC	0.010	Down-regulation
Other_Aur_AurB_ST	Q92538	GBF1	Q96GD4	AURKB	S684	S684F	684	Missense	central	0	yes	0.074	0.000	EPSD	ICGC;COSMIC	0.010	Loss
Other_Aur_AurB_ST	Q92538	GBF1	Q96GD4	AURKB	S684	R678W	678	Missense	distal	-6	no	0.074	0.073	EPSD	ICGC;COSMIC	0.010	Down-regulation
Other_Aur_AurB_ST	Q92538	GBF1	Q96GD4	AURKB	S684	R682L	682	Missense	proximal	-2	no	0.074	0.003	EPSD	ICGC;COSMIC	0.010	Loss
Other_Aur_AurB_ST	Q92538	GBF1	Q96GD4	AURKB	S1453	R1460H	1460	Missense	distal	7	no	0.017	0.016	EPSD	ICGC	0.010	Down-regulation
Other_Aur_AurB_ST	Q92538	GBF1	Q96GD4	AURKB	S1453	R1448H	1448	Missense	distal	-5	no	0.017	0.015	EPSD	ICGC;COSMIC	0.010	Down-regulation
Other_Aur_AurB_ST	Q92538	GBF1	Q96GD4	AURKB	S1453	R1460L	1460	Missense	distal	7	no	0.017	0.016	EPSD	ICGC	0.010	Down-regulation
Other_Aur_AurB_ST	Q92538	GBF1	Q96GD4	AURKB	S1453	K1452R	1452	Missense	proximal	-1	no	0.017	0.023	EPSD	ICGC;COSMIC	0.010	Up-regulation
Other_Aur_AurB_ST	Q92538	GBF1	Q96GD4	AURKB	S1453	R1460C	1460	Missense	distal	7	no	0.017	0.016	EPSD	ICGC;COSMIC	0.010	Down-regulation
Other_Aur_AurB_ST	Q92538	GBF1	Q96GD4	AURKB	T1464	R1461Q	1461	Missense	distal	-3	no	0.010	0.003	EPSD	ICGC	0.010	Loss
Other_Aur_AurB_ST	Q92538	GBF1	Q96GD4	AURKB	T1464	R1460H	1460	Missense	distal	-4	no	0.010	0.009	EPSD	ICGC	0.010	Loss
Other_Aur_AurB_ST	Q92538	GBF1	Q96GD4	AURKB	T1464	R1460L	1460	Missense	distal	-4	no	0.010	0.009	EPSD	ICGC	0.010	Loss
Other_Aur_AurB_ST	Q92538	GBF1	Q96GD4	AURKB	T1464	R1460C	1460	Missense	distal	-4	no	0.010	0.009	EPSD	ICGC;COSMIC	0.010	Loss
Other_Aur_AurB_ST	Q92538	GBF1	Q96GD4	AURKB	S1465	R1461Q	1461	Missense	distal	-4	no	0.071	0.070	EPSD	ICGC	0.010	Down-regulation
Other_Aur_AurB_ST	Q92538	GBF1	Q96GD4	AURKB	S1465	R1460H	1460	Missense	distal	-5	no	0.071	0.069	EPSD	ICGC	0.010	Down-regulation
Other_Aur_AurB_ST	Q92538	GBF1	Q96GD4	AURKB	S1465	R1460L	1460	Missense	distal	-5	no	0.071	0.069	EPSD	ICGC	0.010	Down-regulation
Other_Aur_AurB_ST	Q92538	GBF1	Q96GD4	AURKB	S1465	R1460C	1460	Missense	distal	-5	no	0.071	0.069	EPSD	ICGC;COSMIC	0.010	Down-regulation
Other_Aur_AurB_ST	Q92538	GBF1	Q96GD4	AURKB	S1466	R1461Q	1461	Missense	distal	-5	no	0.011	0.009	EPSD	ICGC	0.010	Loss
Other_Aur_AurB_ST	Q92538	GBF1	Q96GD4	AURKB	S1466	R1460H	1460	Missense	distal	-6	no	0.011	0.010	EPSD	ICGC	0.010	Down-regulation
Other_Aur_AurB_ST	Q92538	GBF1	Q96GD4	AURKB	S1466	R1460L	1460	Missense	distal	-6	no	0.011	0.010	EPSD	ICGC	0.010	Down-regulation
Other_Aur_AurB_ST	Q92538	GBF1	Q96GD4	AURKB	S1466	R1460C	1460	Missense	distal	-6	no	0.011	0.010	EPSD	ICGC;COSMIC	0.010	Down-regulation
Other_Aur_AurB_ST	Q92538	GBF1	Q96GD4	AURKB	S1491	H1488R	1488	Missense	distal	-3	no	0.004	0.010	EPSD	ICGC	0.010	Gain
Other_Aur_AurB_ST	O15392	BIRC5	Q96GD4	AURKB	T117	E116K	116	Missense	proximal	-1	no	0.014	0.016	PhosphoSitePlus;EPSD	ICGC;COSMIC	0.010	Up-regulation
Other_Aur_AurB_ST	Q9Y520	PRRC2C	Q96GD4	AURKB	S924	R923Q	923	Missense	proximal	-1	no	0.026	0.019	EPSD	ICGC;COSMIC	0.010	Down-regulation
Other_Aur_AurB_ST	Q9Y520	PRRC2C	Q96GD4	AURKB	S1246	E1243K	1243	Missense	distal	-3	no	0.014	0.015	EPSD	ICGC;COSMIC	0.010	Up-regulation
Other_Aur_AurB_ST	Q9BXS6	NUSAP1	Q96GD4	AURKB	T33	T33N	33	Missense	central	0	yes	0.075	0.000	EPSD	ICGC;COSMIC	0.010	Loss
Other_Aur_AurB_ST	Q9BXS6	NUSAP1	Q96GD4	AURKB	T33	T33A	33	Missense	central	0	yes	0.075	0.000	EPSD	ICGC;COSMIC	0.010	Loss
Other_Aur_AurB_ST	Q9BXS6	NUSAP1	Q96GD4	AURKB	T33	K37R	37	Missense	distal	4	no	0.075	0.076	EPSD	ICGC	0.010	Up-regulation
Other_Aur_AurB_ST	Q9BXS6	NUSAP1	Q96GD4	AURKB	S154	R152T	152	Missense	proximal	-2	no	0.070	0.003	EPSD	ICGC;COSMIC	0.010	Loss
Other_Aur_AurB_ST	Q9BXS6	NUSAP1	Q96GD4	AURKB	S251	R249Q	249	Missense	proximal	-2	no	0.074	0.000	EPSD	ICGC;COSMIC	0.010	Loss
Other_Aur_AurB_ST	Q9BXS6	NUSAP1	Q96GD4	AURKB	S305	A306S	306	Missense	proximal	1	no	0.073	0.072	EPSD	ICGC	0.010	Down-regulation
Other_Aur_AurB_ST	Q9NYP9	MIS18A	Q96GD4	AURKB	S36	S36A	36	Missense	central	0	yes	0.071	0.000	PhosphoSitePlus	ICGC;COSMIC	0.010	Loss
Other_Aur_AurB_ST	Q9NYP9	MIS18A	Q96GD4	AURKB	S36	L35R	35	Missense	proximal	-1	no	0.071	0.079	PhosphoSitePlus	ICGC	0.010	Up-regulation
Other_Aur_AurB_ST	P46013	MKI67	Q96GD4	AURKB	T109	R116C	116	Missense	distal	7	no	0.020	0.019	EPSD	ICGC	0.010	Down-regulation
Other_Aur_AurB_ST	P46013	MKI67	Q96GD4	AURKB	T109	P112S	112	Missense	distal	3	no	0.020	0.019	EPSD	ICGC	0.010	Down-regulation
Other_Aur_AurB_ST	P46013	MKI67	Q96GD4	AURKB	S125	R123C	123	Missense	proximal	-2	no	0.075	0.005	EPSD	ICGC	0.010	Loss
Other_Aur_AurB_ST	P46013	MKI67	Q96GD4	AURKB	S125	R122H	122	Missense	distal	-3	no	0.075	0.068	EPSD	ICGC;COSMIC;GDSC;CCLE	0.010	Down-regulation
Other_Aur_AurB_ST	P46013	MKI67	Q96GD4	AURKB	S128	R126S	126	Missense	proximal	-2	no	0.074	0.001	EPSD	ICGC	0.010	Loss
Other_Aur_AurB_ST	P46013	MKI67	Q96GD4	AURKB	S128	R123C	123	Missense	distal	-5	no	0.074	0.072	EPSD	ICGC	0.010	Down-regulation
Other_Aur_AurB_ST	P46013	MKI67	Q96GD4	AURKB	S128	R122H	122	Missense	distal	-6	no	0.074	0.072	EPSD	ICGC;COSMIC;GDSC;CCLE	0.010	Down-regulation
Other_Aur_AurB_ST	P46013	MKI67	Q96GD4	AURKB	S292	R290H	290	Missense	proximal	-2	no	0.073	0.002	EPSD	ICGC;COSMIC	0.010	Loss
Other_Aur_AurB_ST	P46013	MKI67	Q96GD4	AURKB	S374	R372L	372	Missense	proximal	-2	no	0.074	0.003	PhosphoSitePlus;EPSD	ICGC;COSMIC	0.010	Loss
Other_Aur_AurB_ST	P46013	MKI67	Q96GD4	AURKB	S374	R372Q	372	Missense	proximal	-2	no	0.074	0.000	PhosphoSitePlus;EPSD	ICGC	0.010	Loss
Other_Aur_AurB_ST	P46013	MKI67	Q96GD4	AURKB	S396	R393G	393	Missense	distal	-3	no	0.018	0.011	EPSD	ICGC;COSMIC	0.010	Down-regulation
Other_Aur_AurB_ST	P46013	MKI67	Q96GD4	AURKB	S396	R393K	393	Missense	distal	-3	no	0.018	0.012	EPSD	ICGC;COSMIC	0.010	Down-regulation
Other_Aur_AurB_ST	P46013	MKI67	Q96GD4	AURKB	S396	R400Q	400	Missense	distal	4	no	0.018	0.017	EPSD	ICGC;COSMIC;GDSC;CCLE	0.010	Down-regulation
Other_Aur_AurB_ST	P46013	MKI67	Q96GD4	AURKB	T401	R400Q	400	Missense	proximal	-1	no	0.012	0.004	EPSD	ICGC;COSMIC;GDSC;CCLE	0.010	Loss
Other_Aur_AurB_ST	P46013	MKI67	Q96GD4	AURKB	S460	S460F	460	Missense	central	0	yes	0.014	0.000	EPSD	ICGC;COSMIC	0.010	Loss
Other_Aur_AurB_ST	P46013	MKI67	Q96GD4	AURKB	S1071	K1069E	1069	Missense	proximal	-2	no	0.016	0.003	EPSD	ICGC;COSMIC	0.010	Loss
Other_Aur_AurB_ST	P46013	MKI67	Q96GD4	AURKB	T1437	T1437M	1437	Missense	central	0	yes	0.071	0.000	EPSD	ICGC;COSMIC	0.010	Loss
Other_Aur_AurB_ST	P46013	MKI67	Q96GD4	AURKB	T1484	T1489P	1489	Missense	distal	5	no	0.011	0.012	EPSD	ICGC;COSMIC	0.010	Up-regulation
Other_Aur_AurB_ST	P46013	MKI67	Q96GD4	AURKB	S1880	P1877T	1877	Missense	distal	-3	no	0.019	0.020	EPSD	ICGC	0.010	Up-regulation
Other_Aur_AurB_ST	P46013	MKI67	Q96GD4	AURKB	T2460	T2460I	2460	Missense	central	0	yes	0.010	0.000	EPSD	ICGC;COSMIC	0.010	Loss
Other_Aur_AurB_ST	P46013	MKI67	Q96GD4	AURKB	T2460	T2460A	2460	Missense	central	0	yes	0.010	0.000	EPSD	ICGC;COSMIC	0.010	Loss
Other_Aur_AurB_ST	P46013	MKI67	Q96GD4	AURKB	S2505	T2508S	2508	Missense	distal	3	no	0.071	0.070	EPSD	ICGC;COSMIC	0.010	Down-regulation
Other_Aur_AurB_ST	P49450	CENPA	Q96GD4	AURKB	S7	R5H	5	Missense	proximal	-2	no	0.082	0.011	PhosphoSitePlus	ICGC;COSMIC	0.010	Down-regulation
Other_Aur_AurB_ST	Q9NS23	RASSF1	Q96GD4	AURKB	T38	R36W	36	Missense	proximal	-2	no	0.070	0.000	EPSD	ICGC	0.010	Loss
Other_Aur_AurB_ST	Q9BW61	DDA1	Q96GD4	AURKB	S28	C25F	25	Missense	distal	-3	no	0.015	0.014	EPSD	ICGC	0.010	Down-regulation
Other_Aur_AurB_ST	Q9BW61	DDA1	Q96GD4	AURKB	S95	S95G	95	Missense	central	0	yes	0.010	0.000	EPSD	ICGC	0.010	Loss
Other_Aur_AurB_ST	Q9NP77	SSU72	Q96GD4	AURKB	T40	T38K	38	Missense	proximal	-2	no	0.004	0.013	EPSD	ICGC;COSMIC	0.010	Gain
Other_Aur_AurB_ST	O00566	MPHOSPH10	Q96GD4	AURKB	T10	R7L	7	Missense	distal	-3	no	0.081	0.074	EPSD	ICGC	0.010	Down-regulation
Other_Aur_AurB_ST	O00566	MPHOSPH10	Q96GD4	AURKB	T10	L11M	11	Missense	proximal	1	no	0.081	0.080	EPSD	ICGC;COSMIC	0.010	Down-regulation
Other_Aur_AurB_ST	O00566	MPHOSPH10	Q96GD4	AURKB	S257	L255R	255	Missense	proximal	-2	no	0.001	0.071	EPSD	ICGC	0.010	Gain
Other_Aur_AurB_ST	O00566	MPHOSPH10	Q96GD4	AURKB	S261	L255R	255	Missense	distal	-6	no	0.014	0.015	EPSD	ICGC	0.010	Up-regulation
Other_Aur_AurB_ST	O00566	MPHOSPH10	Q96GD4	AURKB	T332	R330G	330	Missense	proximal	-2	no	0.069	-0.002	PhosphoSitePlus	ICGC	0.010	Loss
Other_Aur_AurB_ST	O00566	MPHOSPH10	Q96GD4	AURKB	S468	K464N	464	Missense	distal	-4	no	0.014	0.013	EPSD	ICGC;COSMIC	0.010	Down-regulation
Other_Aur_AurB_ST	O00566	MPHOSPH10	Q96GD4	AURKB	S629	E634K	634	Missense	distal	5	no	0.012	0.011	EPSD	ICGC;COSMIC	0.010	Down-regulation
Other_Aur_AurB_ST	Q9NQZ2	UTP3	Q96GD4	AURKB	S56	R57L	57	Missense	proximal	1	no	0.010	0.011	EPSD	ICGC	0.010	Up-regulation
Other_Aur_AurB_ST	Q9NQZ2	UTP3	Q96GD4	AURKB	S150	R148W	148	Missense	proximal	-2	no	0.070	0.000	EPSD	ICGC	0.010	Loss
Other_Aur_AurB_ST	Q9NQZ2	UTP3	Q96GD4	AURKB	S319	R323C	323	Missense	distal	4	no	0.012	0.011	EPSD	ICGC;COSMIC;GDSC	0.010	Down-regulation
Other_Aur_AurB_ST	Q9NQZ2	UTP3	Q96GD4	AURKB	S355	K353M	353	Missense	proximal	-2	no	0.013	0.001	EPSD	ICGC	0.010	Loss
Other_Aur_AurB_ST	Q9NQZ2	UTP3	Q96GD4	AURKB	S462	R469H	469	Missense	distal	7	no	0.072	0.071	PhosphoSitePlus	ICGC;COSMIC	0.010	Down-regulation
Other_Aur_AurB_ST	P14618	PKM	Q96GD4	AURKB	S249	A248G	248	Missense	proximal	-1	no	0.022	0.021	EPSD	ICGC	0.010	Down-regulation
Other_Aur_AurB_ST	O15523	DDX3Y	Q96GD4	AURKB	S288	R290L	290	Missense	proximal	2	no	0.017	0.016	EPSD	ICGC;COSMIC	0.010	Down-regulation
Other_Aur_AurB_ST	O15523	DDX3Y	Q96GD4	AURKB	S592	R598T	598	Missense	distal	6	no	0.068	0.067	PhosphoSitePlus	ICGC;COSMIC	0.010	Down-regulation
Other_Aur_AurB_ST	O15523	DDX3Y	Q96GD4	AURKB	S603	R601Q	601	Missense	proximal	-2	no	0.070	-0.004	EPSD	ICGC;COSMIC	0.010	Loss
Other_Aur_AurB_ST	O15523	DDX3Y	Q96GD4	AURKB	S603	R598T	598	Missense	distal	-5	no	0.070	0.068	EPSD	ICGC;COSMIC	0.010	Down-regulation
Other_Aur_AurB_ST	Q8TE77	SSH3	Q96GD4	AURKB	S37	R35M	35	Missense	proximal	-2	no	0.076	0.005	PhosphoSitePlus	ICGC	0.010	Loss
Other_Aur_AurB_ST	Q8TE77	SSH3	Q96GD4	AURKB	S61	E59K	59	Missense	proximal	-2	no	-0.002	0.012	EPSD	ICGC	0.010	Gain
Other_Aur_AurB_ST	Q15149	PLEC	Q96GD4	AURKB	S1124	R1130Q	1130	Missense	distal	6	no	0.013	0.012	EPSD	ICGC;COSMIC	0.010	Down-regulation
Other_Aur_AurB_ST	Q15149	PLEC	Q96GD4	AURKB	T3785	R3781H	3781	Missense	distal	-4	no	0.073	0.072	EPSD	ICGC;COSMIC	0.010	Down-regulation
Other_Aur_AurB_ST	Q96E39	RBMXL1	Q96GD4	AURKB	S73	G71R	71	Missense	proximal	-2	no	0.002	0.073	EPSD	ICGC	0.010	Gain
Other_Aur_AurB_ST	Q96E39	RBMXL1	Q96GD4	AURKB	S88	R91S	91	Missense	distal	3	no	0.013	0.014	EPSD	ICGC;COSMIC	0.010	Up-regulation
Other_Aur_AurB_ST	Q96E39	RBMXL1	Q96GD4	AURKB	S88	P87T	87	Missense	proximal	-1	no	0.013	0.014	EPSD	ICGC	0.010	Up-regulation
Other_Aur_AurB_ST	Q96E39	RBMXL1	Q96GD4	AURKB	S189	R185H	185	Missense	distal	-4	no	0.072	0.071	EPSD	ICGC;COSMIC;GDSC;CCLE	0.010	Down-regulation
Other_Aur_AurB_ST	Q96E39	RBMXL1	Q96GD4	AURKB	S219	S215C	215	Missense	distal	-4	no	0.013	0.012	EPSD	ICGC;COSMIC	0.010	Down-regulation
Other_Aur_AurB_ST	Q96E39	RBMXL1	Q96GD4	AURKB	S219	R223G	223	Missense	distal	4	no	0.013	0.012	EPSD	ICGC;COSMIC	0.010	Down-regulation
Other_Aur_AurB_ST	Q96E39	RBMXL1	Q96GD4	AURKB	S326	S326G	326	Missense	central	0	yes	0.066	0.000	PhosphoSitePlus	ICGC;COSMIC	0.010	Loss
Other_Aur_AurB_ST	Q09666	AHNAK	Q96GD4	AURKB	T46	R45H	45	Missense	proximal	-1	no	0.010	0.003	EPSD	ICGC;COSMIC	0.010	Loss
Other_Aur_AurB_ST	Q09666	AHNAK	Q96GD4	AURKB	T150	S148R	148	Missense	proximal	-2	no	0.001	0.074	EPSD	ICGC;COSMIC	0.010	Gain
Other_Aur_AurB_ST	Q09666	AHNAK	Q96GD4	AURKB	T152	R149C	149	Missense	distal	-3	no	0.011	0.004	EPSD	ICGC;COSMIC;GDSC	0.010	Loss
Other_Aur_AurB_ST	Q09666	AHNAK	Q96GD4	AURKB	T152	S148R	148	Missense	distal	-4	no	0.011	0.012	EPSD	ICGC;COSMIC	0.010	Up-regulation
Other_Aur_AurB_ST	Q09666	AHNAK	Q96GD4	AURKB	S332	A327E	327	Missense	distal	-5	no	0.070	0.069	EPSD	ICGC	0.010	Down-regulation
Other_Aur_AurB_ST	Q09666	AHNAK	Q96GD4	AURKB	S440	S440Y	440	Missense	central	0	yes	0.011	0.000	EPSD	ICGC	0.010	Loss
Other_Aur_AurB_ST	Q09666	AHNAK	Q96GD4	AURKB	S521	K519T	519	Missense	proximal	-2	no	0.012	0.004	EPSD	ICGC;COSMIC	0.010	Loss
Other_Aur_AurB_ST	Q09666	AHNAK	Q96GD4	AURKB	S521	V520I	520	Missense	proximal	-1	no	0.012	0.013	EPSD	ICGC;COSMIC	0.010	Up-regulation
Other_Aur_AurB_ST	Q09666	AHNAK	Q96GD4	AURKB	S539	K537R	537	Missense	proximal	-2	no	0.012	0.071	EPSD	ICGC;COSMIC	0.010	Up-regulation
Other_Aur_AurB_ST	Q09666	AHNAK	Q96GD4	AURKB	S819	V815A	815	Missense	distal	-4	no	0.010	0.011	EPSD	ICGC;COSMIC	0.010	Up-regulation
Other_Aur_AurB_ST	Q09666	AHNAK	Q96GD4	AURKB	S947	K945R	945	Missense	proximal	-2	no	0.011	0.070	EPSD	ICGC	0.010	Up-regulation
Other_Aur_AurB_ST	Q09666	AHNAK	Q96GD4	AURKB	S1445	E1443K	1443	Missense	proximal	-2	no	-0.002	0.011	EPSD	ICGC	0.010	Gain
Other_Aur_AurB_ST	Q09666	AHNAK	Q96GD4	AURKB	S1452	Q1449H	1449	Missense	distal	-3	no	0.011	0.012	EPSD	ICGC;COSMIC	0.010	Up-regulation
Other_Aur_AurB_ST	Q09666	AHNAK	Q96GD4	AURKB	S1654	K1652N	1652	Missense	proximal	-2	no	0.011	-0.001	EPSD	ICGC;COSMIC	0.010	Loss
Other_Aur_AurB_ST	Q09666	AHNAK	Q96GD4	AURKB	S1856	A1852T	1852	Missense	distal	-4	no	0.011	0.010	EPSD	ICGC;COSMIC	0.010	Down-regulation
Other_Aur_AurB_ST	Q09666	AHNAK	Q96GD4	AURKB	S1990	T1986A	1986	Missense	distal	-4	no	0.010	0.011	EPSD	ICGC;COSMIC	0.010	Up-regulation
Other_Aur_AurB_ST	Q09666	AHNAK	Q96GD4	AURKB	S1990	K1988N	1988	Missense	proximal	-2	no	0.010	-0.001	EPSD	ICGC	0.010	Loss
Other_Aur_AurB_ST	Q09666	AHNAK	Q96GD4	AURKB	S2252	M2246V	2246	Missense	distal	-6	no	0.011	0.010	EPSD	ICGC;COSMIC	0.010	Down-regulation
Other_Aur_AurB_ST	Q09666	AHNAK	Q96GD4	AURKB	S2580	S2580C	2580	Missense	central	0	yes	0.011	0.000	EPSD	ICGC	0.010	Loss
Other_Aur_AurB_ST	Q09666	AHNAK	Q96GD4	AURKB	S2708	K2706R	2706	Missense	proximal	-2	no	0.011	0.070	EPSD	ICGC;COSMIC	0.010	Up-regulation
Other_Aur_AurB_ST	Q09666	AHNAK	Q96GD4	AURKB	S3031	P3028R	3028	Missense	distal	-3	no	0.011	0.018	EPSD	ICGC;COSMIC	0.010	Up-regulation
Other_Aur_AurB_ST	Q09666	AHNAK	Q96GD4	AURKB	S3220	P3217S	3217	Missense	distal	-3	no	0.011	0.012	EPSD	ICGC	0.010	Up-regulation
Other_Aur_AurB_ST	Q09666	AHNAK	Q96GD4	AURKB	S3294	I3293T	3293	Missense	proximal	-1	no	0.010	0.011	EPSD	ICGC;COSMIC	0.010	Up-regulation
Other_Aur_AurB_ST	Q09666	AHNAK	Q96GD4	AURKB	S3294	S3294F	3294	Missense	central	0	yes	0.010	0.000	EPSD	ICGC	0.010	Loss
Other_Aur_AurB_ST	Q09666	AHNAK	Q96GD4	AURKB	S3611	K3609T	3609	Missense	proximal	-2	no	0.011	0.003	EPSD	ICGC;COSMIC	0.010	Loss
Other_Aur_AurB_ST	Q09666	AHNAK	Q96GD4	AURKB	S3746	S3746L	3746	Missense	central	0	yes	0.011	0.000	EPSD	ICGC	0.010	Loss
Other_Aur_AurB_ST	Q09666	AHNAK	Q96GD4	AURKB	S3813	S3813R	3813	Missense	central	0	yes	0.011	0.000	EPSD	ICGC	0.010	Loss
Other_Aur_AurB_ST	Q09666	AHNAK	Q96GD4	AURKB	S3941	K3939N	3939	Missense	proximal	-2	no	0.010	-0.001	EPSD	ICGC	0.010	Loss
Other_Aur_AurB_ST	Q09666	AHNAK	Q96GD4	AURKB	S4002	S4002F	4002	Missense	central	0	yes	0.011	0.000	EPSD	ICGC	0.010	Loss
Other_Aur_AurB_ST	Q09666	AHNAK	Q96GD4	AURKB	S4258	K4253Q	4253	Missense	distal	-5	no	0.011	0.010	EPSD	ICGC;COSMIC	0.010	Down-regulation
Other_Aur_AurB_ST	Q09666	AHNAK	Q96GD4	AURKB	S4258	K4253R	4253	Missense	distal	-5	no	0.011	0.012	EPSD	ICGC;COSMIC	0.010	Up-regulation
Other_Aur_AurB_ST	Q09666	AHNAK	Q96GD4	AURKB	S4386	K4384Q	4384	Missense	proximal	-2	no	0.011	-0.004	EPSD	ICGC;COSMIC	0.010	Loss
Other_Aur_AurB_ST	Q09666	AHNAK	Q96GD4	AURKB	S5386	K5384E	5384	Missense	proximal	-2	no	0.010	-0.003	EPSD	ICGC;COSMIC	0.010	Loss
Other_Aur_AurB_ST	Q09666	AHNAK	Q96GD4	AURKB	S5464	G5463W	5463	Missense	proximal	-1	no	0.012	0.013	EPSD	ICGC;COSMIC	0.010	Up-regulation
Other_Aur_AurB_ST	Q09666	AHNAK	Q96GD4	AURKB	S5780	R5777Q	5777	Missense	distal	-3	no	0.016	0.010	EPSD	ICGC	0.010	Down-regulation
Other_Aur_AurB_ST	Q09666	AHNAK	Q96GD4	AURKB	S5863	S5863F	5863	Missense	central	0	yes	0.070	0.000	EPSD	ICGC;COSMIC	0.010	Loss
Other_Aur_AurB_ST	O76021	RSL1D1	Q96GD4	AURKB	T312	A309D	309	Missense	distal	-3	no	0.066	0.065	PhosphoSitePlus	ICGC;COSMIC	0.010	Down-regulation
Other_Aur_AurB_ST	O76021	RSL1D1	Q96GD4	AURKB	S474	K479T	479	Missense	distal	5	no	0.019	0.020	EPSD	ICGC	0.010	Up-regulation
AGC_RSK_RSKp90_RPS6KA2_ST	Q15349	RPS6KA2	Q15349	RPS6KA2	S26	S24A	24	Missense	proximal	-2	no	15.989	15.788	EPSD	ICGC;COSMIC	8.741	Down-regulation
AGC_RSK_RSKp90_RPS6KA2_ST	Q15349	RPS6KA2	Q15349	RPS6KA2	S26	S28I	28	Missense	proximal	2	no	15.989	15.285	EPSD	ICGC	8.741	Down-regulation
AGC_RSK_RSKp90_RPS6KA2_ST	Q15349	RPS6KA2	Q15349	RPS6KA2	S27	S24A	24	Missense	distal	-3	no	11.448	11.734	EPSD	ICGC;COSMIC	8.741	Up-regulation
AGC_RSK_RSKp90_RPS6KA2_ST	Q15349	RPS6KA2	Q15349	RPS6KA2	S27	S28I	28	Missense	proximal	1	no	11.448	11.372	EPSD	ICGC	8.741	Down-regulation
AGC_RSK_RSKp90_RPS6KA2_ST	Q15349	RPS6KA2	Q15349	RPS6KA2	S28	S24A	24	Missense	distal	-4	no	14.826	13.566	EPSD	ICGC;COSMIC	8.741	Down-regulation
AGC_RSK_RSKp90_RPS6KA2_ST	Q15349	RPS6KA2	Q15349	RPS6KA2	S28	S28I	28	Missense	central	0	yes	14.826	0.000	EPSD	ICGC	8.741	Loss
AGC_RSK_RSKp90_RPS6KA2_ST	Q15349	RPS6KA2	Q15349	RPS6KA2	S30	S24A	24	Missense	distal	-6	no	11.018	10.790	EPSD	ICGC;COSMIC	8.741	Down-regulation
AGC_RSK_RSKp90_RPS6KA2_ST	Q15349	RPS6KA2	Q15349	RPS6KA2	S30	S28I	28	Missense	proximal	-2	no	11.018	10.738	EPSD	ICGC	8.741	Down-regulation
AGC_RSK_RSKp90_RPS6KA2_ST	Q15349	RPS6KA2	Q15349	RPS6KA2	S628	A632V	632	Missense	distal	4	no	13.109	13.111	EPSD	ICGC;COSMIC	8.741	Up-regulation
AGC_RSK_RSKp90_RPS6KA2_ST	P16220	CREB1	Q15349	RPS6KA2	S133	D140A	140	Missense	distal	7	no	13.505	13.374	PhosphoSitePlus	ICGC;COSMIC	8.741	Down-regulation
TK_Src_SrcB_BLK_Y	P12318	FCGR2A	P51451	BLK	Y281	L274P	274	Missense	distal	-7	no	2.051	2.085	EPSD	ICGC;COSMIC	0.806	Up-regulation
TK_Src_SrcB_BLK_Y	P12318	FCGR2A	P51451	BLK	Y281	Y288F	288	Missense	distal	7	no	2.051	2.023	EPSD	ICGC;COSMIC	0.806	Down-regulation
TK_Src_SrcB_BLK_Y	P12318	FCGR2A	P51451	BLK	Y288	Y288F	288	Missense	central	0	yes	2.162	0.000	EPSD;PhosphoSitePlus	ICGC;COSMIC	0.806	Loss
TK_Src_SrcB_BLK_Y	P12318	FCGR2A	P51451	BLK	Y288	P293H	293	Missense	distal	5	no	2.162	2.200	EPSD;PhosphoSitePlus	ICGC;COSMIC	0.806	Up-regulation
TK_Src_SrcB_BLK_Y	P12318	FCGR2A	P51451	BLK	Y304	D298N	298	Missense	distal	-6	no	1.972	1.934	PhosphoSitePlus;EPSD	ICGC;COSMIC	0.806	Down-regulation
TK_Src_SrcB_BLK_Y	P12318	FCGR2A	P51451	BLK	Y304	D299N	299	Missense	distal	-5	no	1.972	1.223	PhosphoSitePlus;EPSD	ICGC;COSMIC	0.806	Down-regulation
TK_Src_SrcB_BLK_Y	P31994	FCGR2B	P51451	BLK	Y292	H297D	297	Missense	distal	5	no	2.045	2.031	PhosphoSitePlus	ICGC;COSMIC	0.806	Down-regulation
TK_Src_SrcB_BLK_Y	P31994	FCGR2B	P51451	BLK	Y292	G285V	285	Missense	distal	-7	no	2.045	2.000	PhosphoSitePlus	ICGC;COSMIC	0.806	Down-regulation
Other_NEK_NEK2_NEK2_ST	Q8N137	CNTROB	P51955	NEK2	S45	E49V	49	Missense	distal	4	no	3.154	3.041	EPSD;PhosphoSitePlus	ICGC;COSMIC	1.575	Down-regulation
Other_NEK_NEK2_NEK2_ST	Q8N137	CNTROB	P51955	NEK2	T570	E563A	563	Missense	distal	-7	no	1.684	1.700	EPSD	ICGC;COSMIC	1.575	Up-regulation
Other_NEK_NEK2_NEK2_ST	Q8N137	CNTROB	P51955	NEK2	T570	E563D	563	Missense	distal	-7	no	1.684	1.582	EPSD	ICGC;COSMIC	1.575	Down-regulation
Other_NEK_NEK2_NEK2_ST	Q8N137	CNTROB	P51955	NEK2	T570	A564D	564	Missense	distal	-6	no	1.684	1.685	EPSD	ICGC	1.575	Up-regulation
Other_NEK_NEK2_NEK2_ST	Q8N137	CNTROB	P51955	NEK2	T570	N576K	576	Missense	distal	6	no	1.684	1.548	EPSD	ICGC;COSMIC	1.575	Loss
Other_NEK_NEK2_NEK2_ST	Q8N137	CNTROB	P51955	NEK2	T571	P578Q	578	Missense	distal	7	no	1.685	1.724	EPSD	ICGC;COSMIC	1.575	Up-regulation
Other_NEK_NEK2_NEK2_ST	Q8N137	CNTROB	P51955	NEK2	T571	A564D	564	Missense	distal	-7	no	1.685	1.567	EPSD	ICGC	1.575	Loss
Other_NEK_NEK2_NEK2_ST	Q8N137	CNTROB	P51955	NEK2	T571	N576K	576	Missense	distal	5	no	1.685	1.793	EPSD	ICGC;COSMIC	1.575	Up-regulation
Other_NEK_NEK2_NEK2_ST	Q8N137	CNTROB	P51955	NEK2	S769	R772W	772	Missense	distal	3	no	1.748	1.825	EPSD	ICGC;COSMIC	1.575	Up-regulation
Other_NEK_NEK2_NEK2_ST	Q8N137	CNTROB	P51955	NEK2	S769	E775V	775	Missense	distal	6	no	1.748	1.849	EPSD	ICGC;COSMIC	1.575	Up-regulation
Other_NEK_NEK2_NEK2_ST	Q8N137	CNTROB	P51955	NEK2	S769	P774S	774	Missense	distal	5	no	1.748	1.635	EPSD	ICGC	1.575	Down-regulation
Other_NEK_NEK2_NEK2_ST	Q8N137	CNTROB	P51955	NEK2	S769	P776H	776	Missense	distal	7	no	1.748	1.777	EPSD	ICGC	1.575	Up-regulation
Other_NEK_NEK2_NEK2_ST	Q8N137	CNTROB	P51955	NEK2	S781	E775V	775	Missense	distal	-6	no	1.599	1.600	EPSD	ICGC;COSMIC	1.575	Up-regulation
Other_NEK_NEK2_NEK2_ST	Q8N137	CNTROB	P51955	NEK2	S781	P774S	774	Missense	distal	-7	no	1.599	1.937	EPSD	ICGC	1.575	Up-regulation
Other_NEK_NEK2_NEK2_ST	P51955	NEK2	P51955	NEK2	T170	D169E	169	Missense	proximal	-1	no	2.885	2.936	EPSD;PhosphoSitePlus	ICGC	1.575	Up-regulation
Other_NEK_NEK2_NEK2_ST	P51955	NEK2	P51955	NEK2	S171	D169E	169	Missense	proximal	-2	no	3.034	3.136	EPSD;PhosphoSitePlus	ICGC	1.575	Up-regulation
Other_NEK_NEK2_NEK2_ST	P51955	NEK2	P51955	NEK2	S241	R239H	239	Missense	proximal	-2	no	3.396	3.384	PhosphoSitePlus;EPSD	ICGC;GDSC;CCLE	1.575	Down-regulation
Other_NEK_NEK2_NEK2_ST	P51955	NEK2	P51955	NEK2	S356	N354S	354	Missense	proximal	-2	no	2.945	2.714	EPSD;PhosphoSitePlus	ICGC;COSMIC	1.575	Down-regulation
Other_NEK_NEK2_NEK2_ST	P51955	NEK2	P51955	NEK2	S356	R361Q	361	Missense	distal	5	no	2.945	2.972	EPSD;PhosphoSitePlus	ICGC;COSMIC	1.575	Up-regulation
Other_NEK_NEK2_NEK2_ST	P51955	NEK2	P51955	NEK2	S356	N354K	354	Missense	proximal	-2	no	2.945	2.779	EPSD;PhosphoSitePlus	ICGC	1.575	Down-regulation
Other_NEK_NEK2_NEK2_ST	P36873	PPP1CC	P51955	NEK2	T307	T311K	311	Missense	distal	4	no	2.056	2.221	PhosphoSitePlus;EPSD	ICGC	1.575	Up-regulation
Other_NEK_NEK2_NEK2_ST	P36873	PPP1CC	P51955	NEK2	T318	T311K	311	Missense	distal	-7	no	1.930	1.820	EPSD;PhosphoSitePlus	ICGC	1.575	Down-regulation
Other_NEK_NEK2_NEK2_ST	P36873	PPP1CC	P51955	NEK2	T318	K319R	319	Missense	proximal	1	no	1.930	1.980	EPSD;PhosphoSitePlus	ICGC;COSMIC	1.575	Up-regulation
Other_NEK_NEK2_NEK2_ST	Q9H2D6	TRIOBP	P51955	NEK2	T594	T599I	599	Missense	distal	5	no	2.002	1.892	EPSD	ICGC;COSMIC	1.575	Down-regulation
Other_NEK_NEK2_NEK2_ST	Q9H2D6	TRIOBP	P51955	NEK2	T594	T599R	599	Missense	distal	5	no	2.002	1.929	EPSD	ICGC;COSMIC;GDSC	1.575	Down-regulation
Other_NEK_NEK2_NEK2_ST	Q9H2D6	TRIOBP	P51955	NEK2	T714	T715I	715	Missense	proximal	1	no	1.575	1.537	EPSD	ICGC;COSMIC	1.575	Loss
Other_NEK_NEK2_NEK2_ST	Q9H2D6	TRIOBP	P51955	NEK2	T714	E718D	718	Missense	distal	4	no	1.575	1.117	EPSD	ICGC;COSMIC	1.575	Loss
Other_NEK_NEK2_NEK2_ST	Q9H2D6	TRIOBP	P51955	NEK2	T714	S710P	710	Missense	distal	-4	no	1.575	1.614	EPSD	ICGC;COSMIC	1.575	Up-regulation
Other_NEK_NEK2_NEK2_ST	Q9H2D6	TRIOBP	P51955	NEK2	T715	T715I	715	Missense	central	0	yes	1.934	0.000	EPSD	ICGC;COSMIC	1.575	Loss
Other_NEK_NEK2_NEK2_ST	Q9H2D6	TRIOBP	P51955	NEK2	T715	E718D	718	Missense	distal	3	no	1.934	1.803	EPSD	ICGC;COSMIC	1.575	Down-regulation
Other_NEK_NEK2_NEK2_ST	Q9H2D6	TRIOBP	P51955	NEK2	T715	S710P	710	Missense	distal	-5	no	1.934	1.983	EPSD	ICGC;COSMIC	1.575	Up-regulation
Other_NEK_NEK2_NEK2_ST	Q9H2D6	TRIOBP	P51955	NEK2	S757	P754L	754	Missense	distal	-3	no	1.652	2.478	EPSD	ICGC;COSMIC	1.575	Up-regulation
Other_NEK_NEK2_NEK2_ST	Q9H2D6	TRIOBP	P51955	NEK2	T817	R816K	816	Missense	proximal	-1	no	2.398	2.001	EPSD	ICGC	1.575	Down-regulation
Other_NEK_NEK2_NEK2_ST	Q9H2D6	TRIOBP	P51955	NEK2	S895	P897L	897	Missense	proximal	2	no	1.687	1.587	EPSD	ICGC;COSMIC	1.575	Down-regulation
Other_NEK_NEK2_NEK2_ST	Q9H2D6	TRIOBP	P51955	NEK2	S895	P892T	892	Missense	distal	-3	no	1.687	1.430	EPSD	ICGC;COSMIC	1.575	Loss
Other_NEK_NEK2_NEK2_ST	Q9H2D6	TRIOBP	P51955	NEK2	S923	T921I	921	Missense	proximal	-2	no	2.266	2.082	EPSD	ICGC	1.575	Down-regulation
Other_NEK_NEK2_NEK2_ST	Q9H2D6	TRIOBP	P51955	NEK2	S1235	P1230L	1230	Missense	distal	-5	no	2.033	2.020	EPSD	ICGC;COSMIC;GDSC	1.575	Down-regulation
Other_NEK_NEK2_NEK2_ST	Q9H2D6	TRIOBP	P51955	NEK2	S1235	R1231C	1231	Missense	distal	-4	no	2.033	1.980	EPSD	ICGC;COSMIC	1.575	Down-regulation
Other_NEK_NEK2_NEK2_ST	Q9H2D6	TRIOBP	P51955	NEK2	S1235	L1240V	1240	Missense	distal	5	no	2.033	2.053	EPSD	ICGC	1.575	Up-regulation
Other_NEK_NEK2_NEK2_ST	Q9H2D6	TRIOBP	P51955	NEK2	S1243	L1240V	1240	Missense	distal	-3	no	1.670	0.650	EPSD	ICGC	1.575	Loss
Other_NEK_NEK2_NEK2_ST	Q9H2D6	TRIOBP	P51955	NEK2	S1243	G1250V	1250	Missense	distal	7	no	1.670	1.722	EPSD	ICGC;COSMIC	1.575	Up-regulation
Other_NEK_NEK2_NEK2_ST	Q9H2D6	TRIOBP	P51955	NEK2	T1684	G1685V	1685	Missense	proximal	1	no	2.990	3.067	EPSD	ICGC	1.575	Up-regulation
Other_NEK_NEK2_NEK2_ST	Q9H2D6	TRIOBP	P51955	NEK2	T1961	R1960S	1960	Missense	proximal	-1	no	1.633	1.367	EPSD	ICGC	1.575	Loss
Other_NEK_NEK2_NEK2_ST	Q9H2D6	TRIOBP	P51955	NEK2	T1961	R1968H	1968	Missense	distal	7	no	1.633	1.669	EPSD	ICGC;COSMIC	1.575	Up-regulation
Other_NEK_NEK2_NEK2_ST	Q9H2D6	TRIOBP	P51955	NEK2	T1961	T1965S	1965	Missense	distal	4	no	1.633	1.539	EPSD	ICGC;COSMIC	1.575	Loss
Other_NEK_NEK2_NEK2_ST	Q9H2D6	TRIOBP	P51955	NEK2	T1961	R1968L	1968	Missense	distal	7	no	1.633	1.682	EPSD	ICGC;COSMIC	1.575	Up-regulation
Other_NEK_NEK2_NEK2_ST	Q9H2D6	TRIOBP	P51955	NEK2	T1993	R1987L	1987	Missense	distal	-6	no	3.137	3.138	EPSD	ICGC;COSMIC	1.575	Up-regulation
Other_NEK_NEK2_NEK2_ST	Q9H2D6	TRIOBP	P51955	NEK2	T1993	E1991Q	1991	Missense	proximal	-2	no	3.137	3.119	EPSD	ICGC;COSMIC	1.575	Down-regulation
Other_NEK_NEK2_NEK2_ST	Q9H2D6	TRIOBP	P51955	NEK2	S2175	S2175C	2175	Missense	central	0	yes	1.901	0.000	EPSD	ICGC;COSMIC	1.575	Loss
Other_NEK_NEK2_NEK2_ST	Q9H2D6	TRIOBP	P51955	NEK2	S2175	R2172Q	2172	Missense	distal	-3	no	1.901	2.311	EPSD	ICGC;COSMIC;GDSC	1.575	Up-regulation
Other_NEK_NEK2_NEK2_ST	Q92997	DVL3	P51955	NEK2	T15	D11G	11	Missense	distal	-4	no	2.112	2.065	PhosphoSitePlus;EPSD	ICGC;COSMIC	1.575	Down-regulation
Other_NEK_NEK2_NEK2_ST	Q92997	DVL3	P51955	NEK2	T15	D11Y	11	Missense	distal	-4	no	2.112	2.037	PhosphoSitePlus;EPSD	ICGC	1.575	Down-regulation
Other_NEK_NEK2_NEK2_ST	Q92997	DVL3	P51955	NEK2	T135	D130E	130	Missense	distal	-5	no	1.636	1.577	EPSD	ICGC;COSMIC	1.575	Down-regulation
Other_NEK_NEK2_NEK2_ST	Q92997	DVL3	P51955	NEK2	T135	N131S	131	Missense	distal	-4	no	1.636	1.626	EPSD	ICGC;COSMIC	1.575	Down-regulation
Other_NEK_NEK2_NEK2_ST	Q92997	DVL3	P51955	NEK2	S280	G284A	284	Missense	distal	4	no	2.946	3.189	EPSD;PhosphoSitePlus	ICGC;COSMIC	1.575	Up-regulation
Other_NEK_NEK2_NEK2_ST	Q92997	DVL3	P51955	NEK2	S642	S639F	639	Missense	distal	-3	no	0.668	1.741	EPSD	ICGC	1.575	Gain
Other_NEK_NEK2_NEK2_ST	Q92997	DVL3	P51955	NEK2	S643	S639F	639	Missense	distal	-4	no	2.943	2.789	EPSD;PhosphoSitePlus	ICGC	1.575	Down-regulation
Other_NEK_NEK2_NEK2_ST	Q92997	DVL3	P51955	NEK2	S697	R702H	702	Missense	distal	5	no	1.985	2.142	EPSD;PhosphoSitePlus	ICGC;COSMIC	1.575	Up-regulation
Other_NEK_NEK2_NEK2_ST	Q92997	DVL3	P51955	NEK2	S697	A696P	696	Missense	proximal	-1	no	1.985	2.080	EPSD;PhosphoSitePlus	ICGC	1.575	Up-regulation
Other_NEK_NEK2_NEK2_ST	Q92997	DVL3	P51955	NEK2	S697	A696S	696	Missense	proximal	-1	no	1.985	2.056	EPSD;PhosphoSitePlus	ICGC;COSMIC	1.575	Up-regulation
Other_NEK_NEK2_NEK2_ST	P54274	TERF1	P51955	NEK2	S7	D4N	4	Missense	distal	-3	no	1.279	2.283	EPSD	ICGC;COSMIC	1.575	Gain
Other_NEK_NEK2_NEK2_ST	Q9BV73	CEP250	P51955	NEK2	T933	E926Q	926	Missense	distal	-7	no	1.608	1.456	EPSD	ICGC	1.575	Loss
Other_NEK_NEK2_NEK2_ST	Q9BV73	CEP250	P51955	NEK2	S1927	L1929F	1929	Missense	proximal	2	no	1.960	1.936	EPSD	ICGC	1.575	Down-regulation
Other_NEK_NEK2_NEK2_ST	P06748	NPM1	P51955	NEK2	S70	Y67D	67	Missense	distal	-3	no	3.055	1.397	PhosphoSitePlus;EPSD	ICGC;COSMIC	1.575	Loss
Other_NEK_NEK2_NEK2_ST	P06748	NPM1	P51955	NEK2	S70	E68K	68	Missense	proximal	-2	no	3.055	2.919	PhosphoSitePlus;EPSD	ICGC;COSMIC	1.575	Down-regulation
Other_NEK_NEK2_NEK2_ST	P06748	NPM1	P51955	NEK2	S70	M65L	65	Missense	distal	-5	no	3.055	3.091	PhosphoSitePlus;EPSD	ICGC;GDSC;CCLE	1.575	Up-regulation
Other_NEK_NEK2_NEK2_ST	P06748	NPM1	P51955	NEK2	S88	G90R	90	Missense	proximal	2	no	3.227	3.203	EPSD;PhosphoSitePlus	ICGC;COSMIC	1.575	Down-regulation
Other_NEK_NEK2_NEK2_ST	P06748	NPM1	P51955	NEK2	S88	S88F	88	Missense	central	0	yes	3.227	0.000	EPSD;PhosphoSitePlus	ICGC;COSMIC	1.575	Loss
Other_NEK_NEK2_NEK2_ST	P06748	NPM1	P51955	NEK2	S139	R142W	142	Missense	distal	3	no	1.497	1.575	EPSD	ICGC	1.575	Gain
Other_NEK_NEK2_NEK2_ST	P06748	NPM1	P51955	NEK2	S143	R142W	142	Missense	proximal	-1	no	1.686	1.551	EPSD	ICGC	1.575	Loss
Other_NEK_NEK2_NEK2_ST	P06748	NPM1	P51955	NEK2	S243	D246Y	246	Missense	distal	3	no	1.455	1.621	EPSD	ICGC	1.575	Gain
Other_NEK_NEK2_NEK2_ST	P06748	NPM1	P51955	NEK2	S260	K263R	263	Missense	distal	3	no	1.629	1.461	EPSD	ICGC;COSMIC	1.575	Loss
Other_NEK_NEK2_NEK2_ST	P06748	NPM1	P51955	NEK2	T279	M278I	278	Missense	proximal	-1	no	0.995	1.584	EPSD	ICGC;COSMIC	1.575	Gain
Other_NEK_NEK2_NEK2_ST	P13639	EEF2	P51955	NEK2	T34	H27N	27	Missense	distal	-7	no	1.331	1.592	EPSD	ICGC	1.575	Gain
Other_NEK_NEK2_NEK2_ST	P13639	EEF2	P51955	NEK2	S279	S279R	279	Missense	central	0	yes	1.616	0.000	EPSD	ICGC;COSMIC	1.575	Loss
Other_NEK_NEK2_NEK2_ST	P13639	EEF2	P51955	NEK2	S279	G282W	282	Missense	distal	3	no	1.616	1.596	EPSD	ICGC;COSMIC	1.575	Down-regulation
Other_NEK_NEK2_NEK2_ST	P13639	EEF2	P51955	NEK2	T423	I429S	429	Missense	distal	6	no	2.317	2.128	EPSD	ICGC	1.575	Down-regulation
Other_NEK_NEK2_NEK2_ST	P13639	EEF2	P51955	NEK2	T423	M430I	430	Missense	distal	7	no	2.317	2.147	EPSD	ICGC;COSMIC	1.575	Down-regulation
Other_NEK_NEK2_NEK2_ST	P13639	EEF2	P51955	NEK2	T482	T482M	482	Missense	central	0	yes	1.585	0.000	EPSD	ICGC;COSMIC	1.575	Loss
Other_NEK_NEK2_NEK2_ST	P13639	EEF2	P51955	NEK2	T482	V480A	480	Missense	proximal	-2	no	1.585	1.635	EPSD	ICGC;COSMIC	1.575	Up-regulation
Other_NEK_NEK2_NEK2_ST	P13639	EEF2	P51955	NEK2	T582	S578L	578	Missense	distal	-4	no	1.751	1.727	EPSD	ICGC;COSMIC	1.575	Down-regulation
Other_NEK_NEK2_NEK2_ST	P13639	EEF2	P51955	NEK2	T582	V577A	577	Missense	distal	-5	no	1.751	1.694	EPSD	ICGC	1.575	Down-regulation
Other_NEK_NEK2_NEK2_ST	P13639	EEF2	P51955	NEK2	S593	H599Q	599	Missense	distal	6	no	1.260	1.581	EPSD	ICGC;COSMIC	1.575	Gain
Other_NEK_NEK2_NEK2_ST	P13639	EEF2	P51955	NEK2	S595	R601Q	601	Missense	distal	6	no	2.095	2.210	PhosphoSitePlus	ICGC;COSMIC	1.575	Up-regulation
Other_NEK_NEK2_NEK2_ST	P13639	EEF2	P51955	NEK2	S595	H599Q	599	Missense	distal	4	no	2.095	1.788	PhosphoSitePlus	ICGC;COSMIC	1.575	Down-regulation
Other_NEK_NEK2_NEK2_ST	P13639	EEF2	P51955	NEK2	T663	G656S	656	Missense	distal	-7	no	1.245	1.700	EPSD	ICGC;COSMIC	1.575	Gain
Other_NEK_NEK2_NEK2_ST	P13639	EEF2	P51955	NEK2	S732	R739C	739	Missense	distal	7	no	1.725	1.766	EPSD	ICGC;COSMIC	1.575	Up-regulation
Other_NEK_NEK2_NEK2_ST	P13639	EEF2	P51955	NEK2	S732	Q737H	737	Missense	distal	5	no	1.725	1.854	EPSD	ICGC	1.575	Up-regulation
Other_NEK_NEK2_NEK2_ST	P13639	EEF2	P51955	NEK2	S732	R727C	727	Missense	distal	-5	no	1.725	1.677	EPSD	ICGC	1.575	Down-regulation
Other_NEK_NEK2_NEK2_ST	P13639	EEF2	P51955	NEK2	S793	A786V	786	Missense	distal	-7	no	1.634	1.525	EPSD	ICGC;COSMIC	1.575	Loss
Other_NEK_NEK2_NEK2_ST	O15360	FANCA	P51955	NEK2	S303	H305Q	305	Missense	proximal	2	no	1.556	1.793	EPSD	ICGC	1.575	Gain
Other_NEK_NEK2_NEK2_ST	O15360	FANCA	P51955	NEK2	S303	H305R	305	Missense	proximal	2	no	1.556	1.786	EPSD	ICGC	1.575	Gain
Other_NEK_NEK2_NEK2_ST	O15360	FANCA	P51955	NEK2	T323	Q326L	326	Missense	distal	3	no	1.658	1.847	EPSD	ICGC;COSMIC	1.575	Up-regulation
Other_NEK_NEK2_NEK2_ST	O15360	FANCA	P51955	NEK2	T351	T351K	351	Missense	central	0	yes	3.148	0.000	PhosphoSitePlus	ICGC	1.575	Loss
Other_NEK_NEK2_NEK2_ST	O15360	FANCA	P51955	NEK2	T1309	A1304T	1304	Missense	distal	-5	no	1.774	1.805	EPSD	ICGC;COSMIC	1.575	Up-regulation
Other_NEK_NEK2_NEK2_ST	O15360	FANCA	P51955	NEK2	T1309	A1304E	1304	Missense	distal	-5	no	1.774	1.793	EPSD	ICGC	1.575	Up-regulation
Other_NEK_NEK2_NEK2_ST	O14777	NDC80	P51955	NEK2	S77	I73M	73	Missense	distal	-4	no	1.618	1.685	EPSD	ICGC;COSMIC	1.575	Up-regulation
Other_NEK_NEK2_NEK2_ST	O14777	NDC80	P51955	NEK2	S77	L71P	71	Missense	distal	-6	no	1.618	1.616	EPSD	ICGC	1.575	Down-regulation
Other_NEK_NEK2_NEK2_ST	Q96CN5	LRRC45	P51955	NEK2	S337	L344I	344	Missense	distal	7	no	1.801	1.746	EPSD	ICGC;COSMIC	1.575	Down-regulation
Other_NEK_NEK2_NEK2_ST	Q96CN5	LRRC45	P51955	NEK2	S337	E343D	343	Missense	distal	6	no	1.801	2.050	EPSD	ICGC;COSMIC	1.575	Up-regulation
Other_NEK_NEK2_NEK2_ST	Q96CN5	LRRC45	P51955	NEK2	S399	M406I	406	Missense	distal	7	no	1.751	1.580	EPSD	ICGC;COSMIC	1.575	Down-regulation
Other_NEK_NEK2_NEK2_ST	Q96CN5	LRRC45	P51955	NEK2	S399	R394S	394	Missense	distal	-5	no	1.751	1.641	EPSD	ICGC	1.575	Down-regulation
Other_NEK_NEK2_NEK2_ST	Q96CN5	LRRC45	P51955	NEK2	S399	E396G	396	Missense	distal	-3	no	1.751	2.203	EPSD	ICGC;COSMIC	1.575	Up-regulation
Other_NEK_NEK2_NEK2_ST	P04637	TP53	P51955	NEK2	S46	D48G	48	Missense	proximal	2	no	2.017	2.134	EPSD	ICGC;COSMIC	1.575	Up-regulation
Other_NEK_NEK2_NEK2_ST	P04637	TP53	P51955	NEK2	S46	Q52K	52	Missense	distal	6	no	2.017	1.689	EPSD	ICGC	1.575	Down-regulation
Other_NEK_NEK2_NEK2_ST	P04637	TP53	P51955	NEK2	T125	T125R	125	Missense	central	0	yes	1.654	0.000	EPSD	ICGC;COSMIC	1.575	Loss
Other_NEK_NEK2_NEK2_ST	P04637	TP53	P51955	NEK2	T125	C124G	124	Missense	proximal	-1	no	1.654	1.878	EPSD	ICGC;COSMIC	1.575	Up-regulation
Other_NEK_NEK2_NEK2_ST	P04637	TP53	P51955	NEK2	T125	C124R	124	Missense	proximal	-1	no	1.654	1.798	EPSD	ICGC;COSMIC;GDSC;CCLE	1.575	Up-regulation
Other_NEK_NEK2_NEK2_ST	P04637	TP53	P51955	NEK2	T125	A119G	119	Missense	distal	-6	no	1.654	1.655	EPSD	ICGC;COSMIC	1.575	Up-regulation
Other_NEK_NEK2_NEK2_ST	P04637	TP53	P51955	NEK2	T125	L130H	130	Missense	distal	5	no	1.654	1.860	EPSD	ICGC;COSMIC	1.575	Up-regulation
Other_NEK_NEK2_NEK2_ST	P04637	TP53	P51955	NEK2	T125	T125A	125	Missense	central	0	yes	1.654	0.000	EPSD	ICGC;COSMIC	1.575	Loss
Other_NEK_NEK2_NEK2_ST	P04637	TP53	P51955	NEK2	T125	K120N	120	Missense	distal	-5	no	1.654	1.704	EPSD	ICGC;COSMIC;GDSC;CCLE	1.575	Up-regulation
Other_NEK_NEK2_NEK2_ST	P04637	TP53	P51955	NEK2	T125	N131Y	131	Missense	distal	6	no	1.654	1.682	EPSD	ICGC;COSMIC	1.575	Up-regulation
Other_NEK_NEK2_NEK2_ST	P04637	TP53	P51955	NEK2	T125	K120M	120	Missense	distal	-5	no	1.654	1.661	EPSD	ICGC;COSMIC	1.575	Up-regulation
Other_NEK_NEK2_NEK2_ST	P04637	TP53	P51955	NEK2	T125	K132M	132	Missense	distal	7	no	1.654	1.707	EPSD	ICGC;COSMIC;CCLE	1.575	Up-regulation
Other_NEK_NEK2_NEK2_ST	P04637	TP53	P51955	NEK2	T125	K120R	120	Missense	distal	-5	no	1.654	1.770	EPSD	ICGC;COSMIC	1.575	Up-regulation
Other_NEK_NEK2_NEK2_ST	P04637	TP53	P51955	NEK2	T125	C124Y	124	Missense	proximal	-1	no	1.654	1.748	EPSD	ICGC;COSMIC	1.575	Up-regulation
Other_NEK_NEK2_NEK2_ST	P04637	TP53	P51955	NEK2	T155	R156L	156	Missense	proximal	1	no	1.836	1.758	EPSD	ICGC;COSMIC	1.575	Down-regulation
Other_NEK_NEK2_NEK2_ST	P04637	TP53	P51955	NEK2	T155	P152R	152	Missense	distal	-3	no	1.836	1.511	EPSD	ICGC;COSMIC	1.575	Loss
Other_NEK_NEK2_NEK2_ST	P04637	TP53	P51955	NEK2	T155	G154S	154	Missense	proximal	-1	no	1.836	1.489	EPSD	ICGC;COSMIC	1.575	Loss
Other_NEK_NEK2_NEK2_ST	P04637	TP53	P51955	NEK2	T155	V157A	157	Missense	proximal	2	no	1.836	1.615	EPSD	ICGC;COSMIC	1.575	Down-regulation
Other_NEK_NEK2_NEK2_ST	P04637	TP53	P51955	NEK2	T155	I162S	162	Missense	distal	7	no	1.836	1.856	EPSD	ICGC;COSMIC	1.575	Up-regulation
Other_NEK_NEK2_NEK2_ST	P04637	TP53	P51955	NEK2	T155	P151F	151	Missense	distal	-4	no	1.836	1.643	EPSD	ICGC;COSMIC	1.575	Down-regulation
Other_NEK_NEK2_NEK2_ST	P04637	TP53	P51955	NEK2	T155	M160R	160	Missense	distal	5	no	1.836	1.683	EPSD	ICGC;COSMIC	1.575	Down-regulation
Other_NEK_NEK2_NEK2_ST	P04637	TP53	P51955	NEK2	S215	P219T	219	Missense	distal	4	no	1.693	1.820	EPSD	ICGC;COSMIC	1.575	Up-regulation
Other_NEK_NEK2_NEK2_ST	P04637	TP53	P51955	NEK2	S215	H214D	214	Missense	proximal	-1	no	1.693	1.903	EPSD	ICGC;COSMIC	1.575	Up-regulation
Other_NEK_NEK2_NEK2_ST	P04637	TP53	P51955	NEK2	S215	Y220N	220	Missense	distal	5	no	1.693	1.757	EPSD	ICGC;COSMIC	1.575	Up-regulation
Other_NEK_NEK2_NEK2_ST	P04637	TP53	P51955	NEK2	S215	E221V	221	Missense	distal	6	no	1.693	1.795	EPSD	ICGC;COSMIC	1.575	Up-regulation
Other_NEK_NEK2_NEK2_ST	P04637	TP53	P51955	NEK2	S215	E221K	221	Missense	distal	6	no	1.693	1.620	EPSD	ICGC;COSMIC	1.575	Down-regulation
Other_NEK_NEK2_NEK2_ST	P04637	TP53	P51955	NEK2	S215	H214Y	214	Missense	proximal	-1	no	1.693	2.101	EPSD	ICGC;COSMIC	1.575	Up-regulation
Other_NEK_NEK2_NEK2_ST	P04637	TP53	P51955	NEK2	S215	T211P	211	Missense	distal	-4	no	1.693	1.814	EPSD	ICGC;COSMIC	1.575	Up-regulation
Other_NEK_NEK2_NEK2_ST	P04637	TP53	P51955	NEK2	S215	F212V	212	Missense	distal	-3	no	1.693	0.241	EPSD	ICGC;COSMIC	1.575	Loss
Other_NEK_NEK2_NEK2_ST	P04637	TP53	P51955	NEK2	S215	D208V	208	Missense	distal	-7	no	1.693	1.702	EPSD	ICGC;COSMIC	1.575	Up-regulation
Other_NEK_NEK2_NEK2_ST	P04637	TP53	P51955	NEK2	S215	V217G	217	Missense	proximal	2	no	1.693	1.648	EPSD	ICGC;COSMIC;CCLE	1.575	Down-regulation
CAMK_PIM_PIM1_ST	Q99683	MAP3K5	P11309	PIM1	S115	S110R	110	Missense	distal	-5	no	0.000	0.001	EPSD	ICGC	0.001	Gain
CAMK_PIM_PIM1_ST	Q99683	MAP3K5	P11309	PIM1	S719	S716R	716	Missense	distal	-3	no	0.001	0.002	EPSD	ICGC	0.001	Up-regulation
CAMK_PIM_PIM1_ST	Q99683	MAP3K5	P11309	PIM1	S719	S719Y	719	Missense	central	0	yes	0.001	0.000	EPSD	ICGC;COSMIC	0.001	Loss
CAMK_PIM_PIM1_ST	Q92934	BAD	P11309	PIM1	S75	R72S	72	Missense	distal	-3	no	0.002	0.001	PhosphoSitePlus	ICGC	0.001	Down-regulation
CAMK_PIM_PIM1_ST	Q92934	BAD	P11309	PIM1	S97	R94W	94	Missense	distal	-3	no	0.001	0.000	EPSD	ICGC	0.001	Loss
CAMK_PIM_PIM1_ST	Q92934	BAD	P11309	PIM1	S99	S99L	99	Missense	central	0	yes	0.002	0.000	EPSD	ICGC	0.001	Loss
CAMK_PIM_PIM1_ST	Q92934	BAD	P11309	PIM1	S99	R94W	94	Missense	distal	-5	no	0.002	0.001	EPSD	ICGC	0.001	Down-regulation
CAMK_PIM_PIM1_ST	P38936	CDKN1A	P11309	PIM1	S31	E28K	28	Missense	distal	-3	no	0.000	0.001	EPSD	ICGC;COSMIC	0.001	Gain
CAMK_PIM_PIM1_ST	P38936	CDKN1A	P11309	PIM1	T145	R143L	143	Missense	proximal	-2	no	0.003	0.002	EPSD;PhosphoSitePlus	ICGC	0.001	Down-regulation
CAMK_PIM_PIM1_ST	P38936	CDKN1A	P11309	PIM1	T145	R142Q	142	Missense	distal	-3	no	0.003	0.002	EPSD;PhosphoSitePlus	ICGC	0.001	Down-regulation
CAMK_PIM_PIM1_ST	P38936	CDKN1A	P11309	PIM1	T145	R140Q	140	Missense	distal	-5	no	0.003	0.002	EPSD;PhosphoSitePlus	ICGC;COSMIC	0.001	Down-regulation
CAMK_PIM_PIM1_ST	P38936	CDKN1A	P11309	PIM1	S146	R143L	143	Missense	distal	-3	no	0.002	0.001	PhosphoSitePlus;EPSD	ICGC	0.001	Down-regulation
CAMK_PIM_PIM1_ST	P27448	MARK3	P11309	PIM1	S428	G423R	423	Missense	distal	-5	no	0.000	0.001	EPSD	ICGC;COSMIC	0.001	Gain
CAMK_PIM_PIM1_ST	P27448	MARK3	P11309	PIM1	S451	S451Y	451	Missense	central	0	yes	0.001	0.000	EPSD	ICGC	0.001	Loss
CAMK_PIM_PIM1_ST	P27448	MARK3	P11309	PIM1	T491	K488N	488	Missense	distal	-3	no	0.002	0.001	EPSD	ICGC;COSMIC	0.001	Down-regulation
CAMK_PIM_PIM1_ST	P27448	MARK3	P11309	PIM1	T507	R504Q	504	Missense	distal	-3	no	0.001	0.000	EPSD	ICGC	0.001	Loss
CAMK_PIM_PIM1_ST	P27448	MARK3	P11309	PIM1	T576	R573Q	573	Missense	distal	-3	no	0.001	0.000	EPSD	ICGC;COSMIC	0.001	Loss
CAMK_PIM_PIM1_ST	P27448	MARK3	P11309	PIM1	T576	R573L	573	Missense	distal	-3	no	0.001	0.000	EPSD	ICGC;COSMIC	0.001	Loss
CAMK_PIM_PIM1_ST	P27448	MARK3	P11309	PIM1	S618	R615M	615	Missense	distal	-3	no	0.001	0.000	EPSD	ICGC;COSMIC	0.001	Loss
CAMK_PIM_PIM1_ST	P35568	IRS1	P11309	PIM1	S189	R184H	184	Missense	distal	-5	no	0.001	0.000	EPSD	ICGC	0.001	Loss
CAMK_PIM_PIM1_ST	P35568	IRS1	P11309	PIM1	S268	R265H	265	Missense	distal	-3	no	0.001	0.000	EPSD	ICGC	0.001	Loss
CAMK_PIM_PIM1_ST	P35568	IRS1	P11309	PIM1	S268	S268I	268	Missense	central	0	yes	0.001	0.000	EPSD	ICGC;COSMIC	0.001	Loss
CAMK_PIM_PIM1_ST	P35568	IRS1	P11309	PIM1	S270	R265H	265	Missense	distal	-5	no	0.002	0.001	EPSD	ICGC	0.001	Down-regulation
CAMK_PIM_PIM1_ST	P35568	IRS1	P11309	PIM1	S272	S272P	272	Missense	central	0	yes	0.002	0.000	EPSD	ICGC	0.001	Loss
CAMK_PIM_PIM1_ST	P35568	IRS1	P11309	PIM1	S413	R410W	410	Missense	distal	-3	no	0.001	0.000	EPSD	ICGC	0.001	Loss
CAMK_PIM_PIM1_ST	P35568	IRS1	P11309	PIM1	S415	R410W	410	Missense	distal	-5	no	0.001	0.000	EPSD	ICGC	0.001	Loss
CAMK_PIM_PIM1_ST	P35568	IRS1	P11309	PIM1	T498	R493C	493	Missense	distal	-5	no	0.001	0.000	EPSD	ICGC	0.001	Loss
CAMK_PIM_PIM1_ST	P35568	IRS1	P11309	PIM1	T498	R493H	493	Missense	distal	-5	no	0.001	0.000	EPSD	ICGC	0.001	Loss
CAMK_PIM_PIM1_ST	P35568	IRS1	P11309	PIM1	S603	R600H	600	Missense	distal	-3	no	0.001	0.000	EPSD	ICGC;COSMIC	0.001	Loss
CAMK_PIM_PIM1_ST	P35568	IRS1	P11309	PIM1	T605	R600H	600	Missense	distal	-5	no	0.001	0.000	EPSD	ICGC;COSMIC	0.001	Loss
CAMK_PIM_PIM1_ST	P35568	IRS1	P11309	PIM1	T793	T793A	793	Missense	central	0	yes	0.001	0.000	EPSD	ICGC;COSMIC	0.001	Loss
CAMK_PIM_PIM1_ST	P35568	IRS1	P11309	PIM1	T793	R790H	790	Missense	distal	-3	no	0.001	0.000	EPSD	ICGC	0.001	Loss
CAMK_PIM_PIM1_ST	P35568	IRS1	P11309	PIM1	S795	R790H	790	Missense	distal	-5	no	0.001	0.000	EPSD	ICGC	0.001	Loss
CAMK_PIM_PIM1_ST	P35568	IRS1	P11309	PIM1	T870	K867T	867	Missense	distal	-3	no	0.001	0.000	EPSD	ICGC	0.001	Loss
CAMK_PIM_PIM1_ST	P35568	IRS1	P11309	PIM1	S974	G971R	971	Missense	distal	-3	no	0.000	0.001	EPSD	ICGC;COSMIC	0.001	Gain
CAMK_PIM_PIM1_ST	P35568	IRS1	P11309	PIM1	S1216	L1211R	1211	Missense	distal	-5	no	0.000	0.001	EPSD	ICGC;COSMIC	0.001	Gain
CAMK_PIM_PIM1_ST	P35568	IRS1	P11309	PIM1	S1223	R1220H	1220	Missense	distal	-3	no	0.001	0.000	EPSD	ICGC;COSMIC	0.001	Loss
CAMK_PIM_PIM1_ST	Q00987	MDM2	P11309	PIM1	S17	G12R	12	Missense	distal	-5	no	0.000	0.001	EPSD	ICGC;COSMIC	0.001	Gain
CAMK_PIM_PIM1_ST	Q00987	MDM2	P11309	PIM1	S190	S190C	190	Missense	central	0	yes	0.001	0.000	EPSD	ICGC;COSMIC	0.001	Loss
CAMK_PIM_PIM1_ST	O43524	FOXO3	P11309	PIM1	S181	K176R	176	Missense	distal	-5	no	0.001	0.002	EPSD	ICGC;COSMIC	0.001	Up-regulation
CAMK_PIM_PIM1_ST	O43524	FOXO3	P11309	PIM1	S446	N441K	441	Missense	distal	-5	no	0.000	0.001	EPSD	ICGC	0.001	Gain
CAMK_PIM_PIM1_ST	O43524	FOXO3	P11309	PIM1	S551	R548C	548	Missense	distal	-3	no	0.001	0.000	EPSD	ICGC;COSMIC	0.001	Loss
CAMK_PIM_PIM1_ST	O43524	FOXO3	P11309	PIM1	S553	R548C	548	Missense	distal	-5	no	0.001	0.000	EPSD	ICGC;COSMIC	0.001	Loss
CAMK_PIM_PIM1_ST	P29474	NOS3	P11309	PIM1	T33	T33I	33	Missense	central	0	yes	0.001	0.000	EPSD	ICGC	0.001	Loss
CAMK_PIM_PIM1_ST	P29474	NOS3	P11309	PIM1	S102	S102F	102	Missense	central	0	yes	0.002	0.000	EPSD	ICGC	0.001	Loss
CAMK_PIM_PIM1_ST	P29474	NOS3	P11309	PIM1	S102	R98C	98	Missense	distal	-4	no	0.002	0.001	EPSD	ICGC	0.001	Down-regulation
CAMK_PIM_PIM1_ST	P29474	NOS3	P11309	PIM1	S617	S617P	617	Missense	central	0	yes	0.001	0.000	EPSD	ICGC;COSMIC	0.001	Loss
CAMK_PIM_PIM1_ST	P29474	NOS3	P11309	PIM1	S633	R628W	628	Missense	distal	-5	no	0.003	0.001	PhosphoSitePlus	ICGC;COSMIC	0.001	Down-regulation
CAMK_PIM_PIM1_ST	P29474	NOS3	P11309	PIM1	T785	R782C	782	Missense	distal	-3	no	0.001	0.000	EPSD	ICGC;COSMIC	0.001	Loss
CAMK_PIM_PIM1_ST	P29474	NOS3	P11309	PIM1	S1179	Q1176E	1176	Missense	distal	-3	no	0.002	0.001	EPSD	ICGC;COSMIC	0.001	Down-regulation
CAMK_PIM_PIM1_ST	Q9Y4H2	IRS2	P11309	PIM1	S306	R303C	303	Missense	distal	-3	no	0.002	0.001	EPSD	ICGC;COSMIC	0.001	Down-regulation
CAMK_PIM_PIM1_ST	Q9Y4H2	IRS2	P11309	PIM1	S306	S306R	306	Missense	central	0	yes	0.002	0.000	EPSD	ICGC	0.001	Loss
CAMK_PIM_PIM1_ST	Q9Y4H2	IRS2	P11309	PIM1	S306	S306N	306	Missense	central	0	yes	0.002	0.000	EPSD	ICGC	0.001	Loss
CAMK_PIM_PIM1_ST	Q9Y4H2	IRS2	P11309	PIM1	S308	R303C	303	Missense	distal	-5	no	0.002	0.001	EPSD	ICGC;COSMIC	0.001	Down-regulation
CAMK_PIM_PIM1_ST	Q9Y4H2	IRS2	P11309	PIM1	S309	S306R	306	Missense	distal	-3	no	0.000	0.001	EPSD	ICGC	0.001	Gain
CAMK_PIM_PIM1_ST	Q9Y4H2	IRS2	P11309	PIM1	S311	S306R	306	Missense	distal	-5	no	0.000	0.001	EPSD	ICGC	0.001	Gain
CAMK_PIM_PIM1_ST	Q9Y4H2	IRS2	P11309	PIM1	S346	R343C	343	Missense	distal	-3	no	0.002	0.001	EPSD	ICGC;COSMIC	0.001	Down-regulation
CAMK_PIM_PIM1_ST	Q9Y4H2	IRS2	P11309	PIM1	S432	S432P	432	Missense	central	0	yes	0.001	0.000	EPSD	ICGC	0.001	Loss
CAMK_PIM_PIM1_ST	Q9Y4H2	IRS2	P11309	PIM1	S749	R744C	744	Missense	distal	-5	no	0.001	0.000	EPSD	ICGC;COSMIC	0.001	Loss
CAMK_PIM_PIM1_ST	Q9Y4H2	IRS2	P11309	PIM1	T891	T891M	891	Missense	central	0	yes	0.002	0.000	EPSD	ICGC	0.001	Loss
CAMK_PIM_PIM1_ST	Q9Y4H2	IRS2	P11309	PIM1	S894	T891M	891	Missense	distal	-3	no	0.002	0.001	EPSD	ICGC	0.001	Down-regulation
CAMK_PIM_PIM1_ST	Q9Y4H2	IRS2	P11309	PIM1	S894	R892C	892	Missense	proximal	-2	no	0.002	0.001	EPSD	ICGC;COSMIC	0.001	Down-regulation
CAMK_PIM_PIM1_ST	Q9Y4H2	IRS2	P11309	PIM1	S973	S973F	973	Missense	central	0	yes	0.001	0.000	EPSD	ICGC;COSMIC	0.001	Loss
CAMK_PIM_PIM1_ST	Q9Y4H2	IRS2	P11309	PIM1	S1149	R1146C	1146	Missense	distal	-3	no	0.003	0.002	PhosphoSitePlus	ICGC;COSMIC;CCLE	0.001	Down-regulation
CAMK_PIM_PIM1_ST	Q9Y4H2	IRS2	P11309	PIM1	S1149	R1144H	1144	Missense	distal	-5	no	0.003	0.001	PhosphoSitePlus	ICGC;COSMIC	0.001	Down-regulation
CAMK_PIM_PIM1_ST	Q9Y4H2	IRS2	P11309	PIM1	S1149	R1144S	1144	Missense	distal	-5	no	0.003	0.001	PhosphoSitePlus	ICGC	0.001	Down-regulation
CAMK_PIM_PIM1_ST	Q9Y4H2	IRS2	P11309	PIM1	T1151	R1146C	1146	Missense	distal	-5	no	0.001	0.000	EPSD	ICGC;COSMIC;CCLE	0.001	Loss
CAMK_PIM_PIM1_ST	Q9Y4H2	IRS2	P11309	PIM1	S1282	G1279R	1279	Missense	distal	-3	no	0.000	0.001	EPSD	ICGC;COSMIC	0.001	Gain
CAMK_PIM_PIM1_ST	P46527	CDKN1B	P11309	PIM1	S83	E78K	78	Missense	distal	-5	no	0.000	0.001	EPSD	ICGC;COSMIC	0.001	Gain
CAMK_PIM_PIM1_ST	P46527	CDKN1B	P11309	PIM1	T198	P191H	191	Missense	distal	-7	no	0.001	0.002	EPSD;PhosphoSitePlus	ICGC;COSMIC	0.001	Up-regulation
CAMK_PIM_PIM1_ST	O60381	HBP1	P11309	PIM1	S156	R151C	151	Missense	distal	-5	no	0.001	0.000	EPSD	ICGC;COSMIC;GDSC	0.001	Loss
CAMK_PIM_PIM1_ST	O60381	HBP1	P11309	PIM1	S156	R151S	151	Missense	distal	-5	no	0.001	0.000	EPSD	ICGC;COSMIC	0.001	Loss
CAMK_PIM_PIM1_ST	O60381	HBP1	P11309	PIM1	S380	R375P	375	Missense	distal	-5	no	0.003	0.001	PhosphoSitePlus;EPSD	ICGC	0.001	Down-regulation
CAMK_PIM_PIM1_ST	Q9UNQ0	ABCG2	P11309	PIM1	S50	R45L	45	Missense	distal	-5	no	0.002	0.001	EPSD	ICGC;COSMIC	0.001	Down-regulation
CAMK_PIM_PIM1_ST	Q9UNQ0	ABCG2	P11309	PIM1	S143	E138K	138	Missense	distal	-5	no	0.000	0.001	EPSD	ICGC;COSMIC	0.001	Gain
CAMK_PIM_PIM1_ST	Q04206	RELA	P11309	PIM1	T136	R133C	133	Missense	distal	-3	no	0.001	0.000	EPSD	ICGC	0.001	Loss
CAMK_PIM_PIM1_ST	Q04206	RELA	P11309	PIM1	S203	R198Q	198	Missense	distal	-5	no	0.001	0.000	EPSD	ICGC	0.001	Loss
CAMK_PIM_PIM1_ST	Q04206	RELA	P11309	PIM1	S203	S203Y	203	Missense	central	0	yes	0.001	0.000	EPSD	ICGC	0.001	Loss
CAMK_PIM_PIM1_ST	Q04206	RELA	P11309	PIM1	S335	R330H	330	Missense	distal	-5	no	0.001	0.000	EPSD	ICGC;COSMIC	0.001	Loss
CAMK_PIM_PIM1_ST	Q04206	RELA	P11309	PIM1	T505	T505K	505	Missense	central	0	yes	0.001	0.000	EPSD	ICGC	0.001	Loss
CAMK_PIM_PIM1_ST	P10275	AR	P11309	PIM1	S96	E93K	93	Missense	distal	-3	no	0.000	0.001	EPSD	ICGC	0.001	Gain
CAMK_PIM_PIM1_ST	P10275	AR	P11309	PIM1	S516	S516I	516	Missense	central	0	yes	0.001	0.000	EPSD	ICGC	0.001	Loss
CAMK_PIM_PIM1_ST	P10275	AR	P11309	PIM1	S792	R789S	789	Missense	distal	-3	no	0.002	0.001	EPSD	ICGC	0.001	Down-regulation
STE_STE20_MST_STK4_ST	Q14457	BECN1	Q13043	STK4	S7	Q13R	13	Missense	distal	6	no	4.905	4.916	EPSD	ICGC;COSMIC	4.850	Up-regulation
STE_STE20_MST_STK4_ST	Q14457	BECN1	Q13043	STK4	S7	M12I	12	Missense	distal	5	no	4.905	4.902	EPSD	ICGC;COSMIC	4.850	Down-regulation
STE_STE20_MST_STK4_ST	Q14457	BECN1	Q13043	STK4	S7	T6M	6	Missense	proximal	-1	no	4.905	4.898	EPSD	ICGC;COSMIC	4.850	Down-regulation
STE_STE20_MST_STK4_ST	Q14457	BECN1	Q13043	STK4	S10	Q13R	13	Missense	distal	3	no	4.885	4.878	EPSD	ICGC;COSMIC	4.850	Down-regulation
STE_STE20_MST_STK4_ST	Q14457	BECN1	Q13043	STK4	S10	M12I	12	Missense	proximal	2	no	4.885	4.891	EPSD	ICGC;COSMIC	4.850	Up-regulation
STE_STE20_MST_STK4_ST	Q14457	BECN1	Q13043	STK4	T11	Q13R	13	Missense	proximal	2	no	4.982	5.037	EPSD	ICGC;COSMIC	4.850	Up-regulation
STE_STE20_MST_STK4_ST	Q14457	BECN1	Q13043	STK4	T11	M12I	12	Missense	proximal	1	no	4.982	4.965	EPSD	ICGC;COSMIC	4.850	Down-regulation
STE_STE20_MST_STK4_ST	Q14457	BECN1	Q13043	STK4	T11	T6M	6	Missense	distal	-5	no	4.982	4.945	EPSD	ICGC;COSMIC	4.850	Down-regulation
STE_STE20_MST_STK4_ST	Q14457	BECN1	Q13043	STK4	S15	Q13R	13	Missense	proximal	-2	no	4.947	4.964	EPSD	ICGC;COSMIC	4.850	Up-regulation
STE_STE20_MST_STK4_ST	Q14457	BECN1	Q13043	STK4	S15	M12I	12	Missense	distal	-3	no	4.947	4.954	EPSD	ICGC;COSMIC	4.850	Up-regulation
STE_STE20_MST_STK4_ST	Q14457	BECN1	Q13043	STK4	S15	R20H	20	Missense	distal	5	no	4.947	4.946	EPSD	ICGC;COSMIC	4.850	Down-regulation
STE_STE20_MST_STK4_ST	Q14457	BECN1	Q13043	STK4	T38	L42F	42	Missense	distal	4	no	4.847	4.863	EPSD	ICGC	4.850	Gain
STE_STE20_MST_STK4_ST	Q14457	BECN1	Q13043	STK4	T38	P45S	45	Missense	distal	7	no	4.847	4.851	EPSD	ICGC	4.850	Gain
STE_STE20_MST_STK4_ST	Q14457	BECN1	Q13043	STK4	T38	Q40K	40	Missense	proximal	2	no	4.847	4.913	EPSD	ICGC;COSMIC	4.850	Gain
STE_STE20_MST_STK4_ST	Q14457	BECN1	Q13043	STK4	T48	P45A	45	Missense	distal	-3	no	4.836	4.856	EPSD	ICGC;COSMIC	4.850	Gain
STE_STE20_MST_STK4_ST	Q14457	BECN1	Q13043	STK4	T48	A52V	52	Missense	distal	4	no	4.836	4.852	EPSD	ICGC	4.850	Gain
STE_STE20_MST_STK4_ST	Q14457	BECN1	Q13043	STK4	S64	P68T	68	Missense	distal	4	no	4.912	4.896	EPSD	ICGC;COSMIC	4.850	Down-regulation
STE_STE20_MST_STK4_ST	Q14457	BECN1	Q13043	STK4	T72	P68T	68	Missense	distal	-4	no	4.913	4.912	EPSD	ICGC;COSMIC	4.850	Down-regulation
STE_STE20_MST_STK4_ST	Q14457	BECN1	Q13043	STK4	T91	P85Q	85	Missense	distal	-6	no	4.851	4.829	EPSD	ICGC	4.850	Loss
STE_STE20_MST_STK4_ST	Q14457	BECN1	Q13043	STK4	T108	D105N	105	Missense	distal	-3	no	4.899	4.902	PhosphoSitePlus	ICGC	4.850	Up-regulation
STE_STE20_MST_STK4_ST	Q14457	BECN1	Q13043	STK4	T108	A103E	103	Missense	distal	-5	no	4.899	4.924	PhosphoSitePlus	ICGC	4.850	Up-regulation
STE_STE20_MST_STK4_ST	Q14457	BECN1	Q13043	STK4	T108	S113R	113	Missense	distal	5	no	4.899	4.812	PhosphoSitePlus	ICGC	4.850	Loss
STE_STE20_MST_STK4_ST	Q14457	BECN1	Q13043	STK4	S409	I415M	415	Missense	distal	6	no	4.872	4.868	EPSD	ICGC	4.850	Down-regulation
STE_STE20_MST_STK4_ST	Q14457	BECN1	Q13043	STK4	S409	D405G	405	Missense	distal	-4	no	4.872	4.871	EPSD	ICGC;COSMIC	4.850	Down-regulation
STE_STE20_MST_STK4_ST	Q14457	BECN1	Q13043	STK4	T417	I415M	415	Missense	proximal	-2	no	4.873	4.869	EPSD	ICGC	4.850	Down-regulation
STE_STE20_MST_STK4_ST	Q06830	PRDX1	Q13043	STK4	T18	G24S	24	Missense	distal	6	no	4.889	4.899	EPSD;PhosphoSitePlus	ICGC;COSMIC	4.850	Up-regulation
STE_STE20_MST_STK4_ST	Q06830	PRDX1	Q13043	STK4	T18	A12T	12	Missense	distal	-6	no	4.889	4.901	EPSD;PhosphoSitePlus	ICGC;COSMIC	4.850	Up-regulation
STE_STE20_MST_STK4_ST	P19429	TNNI3	Q13043	STK4	S5	A2V	2	Missense	distal	-3	no	4.878	4.868	EPSD	ICGC;COSMIC	4.850	Down-regulation
STE_STE20_MST_STK4_ST	P19429	TNNI3	Q13043	STK4	S5	S6Y	6	Missense	proximal	1	no	4.878	4.906	EPSD	ICGC	4.850	Up-regulation
STE_STE20_MST_STK4_ST	P19429	TNNI3	Q13043	STK4	S23	R27S	27	Missense	distal	4	no	4.968	4.994	EPSD	ICGC	4.850	Up-regulation
STE_STE20_MST_STK4_ST	P19429	TNNI3	Q13043	STK4	S23	R21S	21	Missense	proximal	-2	no	4.968	4.951	EPSD	ICGC	4.850	Down-regulation
STE_STE20_MST_STK4_ST	P19429	TNNI3	Q13043	STK4	S23	S24F	24	Missense	proximal	1	no	4.968	4.982	EPSD	ICGC;COSMIC	4.850	Up-regulation
STE_STE20_MST_STK4_ST	P19429	TNNI3	Q13043	STK4	S23	R21L	21	Missense	proximal	-2	no	4.968	4.946	EPSD	ICGC;COSMIC	4.850	Down-regulation
STE_STE20_MST_STK4_ST	P19429	TNNI3	Q13043	STK4	T143	R145W	145	Missense	proximal	2	no	4.934	4.888	EPSD;PhosphoSitePlus	ICGC;COSMIC;GDSC;CCLE	4.850	Down-regulation
STE_STE20_MST_STK4_ST	Q13043	STK4	Q13043	STK4	S21	E28K	28	Missense	distal	7	no	4.871	4.864	EPSD	ICGC	4.850	Down-regulation
STE_STE20_MST_STK4_ST	Q13043	STK4	Q13043	STK4	S21	L17S	17	Missense	distal	-4	no	4.871	4.870	EPSD	ICGC;COSMIC	4.850	Down-regulation
STE_STE20_MST_STK4_ST	Q13043	STK4	Q13043	STK4	T23	E28K	28	Missense	distal	5	no	4.974	4.958	EPSD	ICGC	4.850	Down-regulation
STE_STE20_MST_STK4_ST	Q13043	STK4	Q13043	STK4	T23	V29L	29	Missense	distal	6	no	4.974	4.970	EPSD	ICGC	4.850	Down-regulation
STE_STE20_MST_STK4_ST	Q13043	STK4	Q13043	STK4	T23	L17S	17	Missense	distal	-6	no	4.974	4.957	EPSD	ICGC;COSMIC	4.850	Down-regulation
STE_STE20_MST_STK4_ST	Q13043	STK4	Q13043	STK4	S307	Q309E	309	Missense	proximal	2	no	4.846	4.901	EPSD	ICGC;COSMIC	4.850	Gain
STE_STE20_MST_STK4_ST	P00519	ABL1	Q13043	STK4	S50	R47C	47	Missense	distal	-3	no	4.893	4.869	EPSD	ICGC;COSMIC	4.850	Down-regulation
STE_STE20_MST_STK4_ST	P00519	ABL1	Q13043	STK4	S50	A56T	56	Missense	distal	6	no	4.893	4.895	EPSD	ICGC;COSMIC	4.850	Up-regulation
STE_STE20_MST_STK4_ST	P00519	ABL1	Q13043	STK4	S50	A46T	46	Missense	distal	-4	no	4.893	4.894	EPSD	ICGC;COSMIC	4.850	Up-regulation
STE_STE20_MST_STK4_ST	P00519	ABL1	Q13043	STK4	S154	R152C	152	Missense	proximal	-2	no	4.904	4.889	EPSD	ICGC;COSMIC	4.850	Down-regulation
STE_STE20_MST_STK4_ST	P00519	ABL1	Q13043	STK4	S154	R161M	161	Missense	distal	7	no	4.904	4.899	EPSD	ICGC;COSMIC	4.850	Down-regulation
STE_STE20_MST_STK4_ST	P00519	ABL1	Q13043	STK4	S157	R152C	152	Missense	distal	-5	no	4.874	4.889	EPSD	ICGC;COSMIC	4.850	Up-regulation
STE_STE20_MST_STK4_ST	P00519	ABL1	Q13043	STK4	S157	S164L	164	Missense	distal	7	no	4.874	4.870	EPSD	ICGC;CCLE	4.850	Down-regulation
STE_STE20_MST_STK4_ST	P00519	ABL1	Q13043	STK4	S157	R161M	161	Missense	distal	4	no	4.874	4.850	EPSD	ICGC;COSMIC	4.850	Down-regulation
STE_STE20_MST_STK4_ST	P00519	ABL1	Q13043	STK4	S187	T194A	194	Missense	distal	7	no	4.875	4.880	EPSD	ICGC;COSMIC	4.850	Up-regulation
STE_STE20_MST_STK4_ST	P00519	ABL1	Q13043	STK4	S187	E189G	189	Missense	proximal	2	no	4.875	4.791	EPSD	ICGC;COSMIC	4.850	Loss
STE_STE20_MST_STK4_ST	P00519	ABL1	Q13043	STK4	S187	V186I	186	Missense	proximal	-1	no	4.875	4.876	EPSD	ICGC;COSMIC	4.850	Up-regulation
STE_STE20_MST_STK4_ST	P00519	ABL1	Q13043	STK4	T243	H246Y	246	Missense	distal	3	no	4.925	4.927	EPSD	ICGC;COSMIC	4.850	Up-regulation
STE_STE20_MST_STK4_ST	P00519	ABL1	Q13043	STK4	T243	G250R	250	Missense	distal	7	no	4.925	4.921	EPSD	ICGC;COSMIC	4.850	Down-regulation
STE_STE20_MST_STK4_ST	P00519	ABL1	Q13043	STK4	S265	T267M	267	Missense	proximal	2	no	4.897	4.834	EPSD	ICGC;COSMIC	4.850	Loss
STE_STE20_MST_STK4_ST	P00519	ABL1	Q13043	STK4	T610	R617H	617	Missense	distal	7	no	4.848	4.852	EPSD	ICGC;COSMIC	4.850	Gain
STE_STE20_MST_STK4_ST	P00519	ABL1	Q13043	STK4	S620	M624I	624	Missense	distal	4	no	4.842	4.869	EPSD	ICGC;COSMIC	4.850	Gain
STE_STE20_MST_STK4_ST	P00519	ABL1	Q13043	STK4	S691	H685R	685	Missense	distal	-6	no	4.884	4.874	EPSD	ICGC;COSMIC	4.850	Down-regulation
STE_STE20_MST_STK4_ST	P00519	ABL1	Q13043	STK4	S691	K688N	688	Missense	distal	-3	no	4.884	4.851	EPSD	ICGC;COSMIC	4.850	Down-regulation
STE_STE20_MST_STK4_ST	P00519	ABL1	Q13043	STK4	S691	T692M	692	Missense	proximal	1	no	4.884	4.923	EPSD	ICGC	4.850	Up-regulation
STE_STE20_MST_STK4_ST	P00519	ABL1	Q13043	STK4	S804	P806S	806	Missense	proximal	2	no	4.867	4.861	EPSD	ICGC;COSMIC	4.850	Down-regulation
STE_STE20_MST_STK4_ST	P00519	ABL1	Q13043	STK4	S855	S859L	859	Missense	distal	4	no	4.892	4.839	EPSD	ICGC	4.850	Loss
STE_STE20_MST_STK4_ST	P00519	ABL1	Q13043	STK4	S855	E849Q	849	Missense	distal	-6	no	4.892	4.880	EPSD	ICGC;COSMIC	4.850	Down-regulation
STE_STE20_MST_STK4_ST	P00519	ABL1	Q13043	STK4	S855	T852P	852	Missense	distal	-3	no	4.892	4.853	EPSD	ICGC;COSMIC	4.850	Down-regulation
STE_STE20_MST_STK4_ST	P00519	ABL1	Q13043	STK4	S859	S859L	859	Missense	central	0	yes	4.920	0.000	EPSD	ICGC	4.850	Loss
STE_STE20_MST_STK4_ST	P00519	ABL1	Q13043	STK4	S859	T852P	852	Missense	distal	-7	no	4.920	4.922	EPSD	ICGC;COSMIC	4.850	Up-regulation
STE_STE20_MST_STK4_ST	P00519	ABL1	Q13043	STK4	S1115	K1122M	1122	Missense	distal	7	no	4.836	4.853	EPSD	ICGC;COSMIC	4.850	Gain
STE_STE20_MST_STK4_ST	O43524	FOXO3	Q13043	STK4	S12	P10T	10	Missense	proximal	-2	no	4.959	4.973	EPSD	ICGC;COSMIC	4.850	Up-regulation
STE_STE20_MST_STK4_ST	O43524	FOXO3	Q13043	STK4	S200	G198C	198	Missense	proximal	-2	no	4.885	4.898	EPSD	ICGC;COSMIC	4.850	Up-regulation
STE_STE20_MST_STK4_ST	O43524	FOXO3	Q13043	STK4	S200	D199N	199	Missense	proximal	-1	no	4.885	4.884	EPSD	ICGC;COSMIC	4.850	Down-regulation
STE_STE20_MST_STK4_ST	O43524	FOXO3	Q13043	STK4	S209	R211Q	211	Missense	proximal	2	no	5.012	4.957	EPSD;PhosphoSitePlus	ICGC;COSMIC	4.850	Down-regulation
STE_STE20_MST_STK4_ST	O43524	FOXO3	Q13043	STK4	S209	R211W	211	Missense	proximal	2	no	5.012	4.966	EPSD;PhosphoSitePlus	ICGC;COSMIC	4.850	Down-regulation
STE_STE20_MST_STK4_ST	O43524	FOXO3	Q13043	STK4	S215	R211Q	211	Missense	distal	-4	no	4.998	4.999	EPSD;PhosphoSitePlus	ICGC;COSMIC	4.850	Up-regulation
STE_STE20_MST_STK4_ST	O43524	FOXO3	Q13043	STK4	S215	R222Q	222	Missense	distal	7	no	4.998	5.005	EPSD;PhosphoSitePlus	ICGC;COSMIC;CCLE	4.850	Up-regulation
STE_STE20_MST_STK4_ST	O43524	FOXO3	Q13043	STK4	S215	R222L	222	Missense	distal	7	no	4.998	4.997	EPSD;PhosphoSitePlus	ICGC;COSMIC	4.850	Down-regulation
STE_STE20_MST_STK4_ST	O43524	FOXO3	Q13043	STK4	S215	R211W	211	Missense	distal	-4	no	4.998	4.999	EPSD;PhosphoSitePlus	ICGC;COSMIC	4.850	Up-regulation
STE_STE20_MST_STK4_ST	O43524	FOXO3	Q13043	STK4	T228	I235N	235	Missense	distal	7	no	4.912	4.906	EPSD	ICGC	4.850	Down-regulation
STE_STE20_MST_STK4_ST	O43524	FOXO3	Q13043	STK4	T228	R222Q	222	Missense	distal	-6	no	4.912	4.923	EPSD	ICGC;COSMIC;CCLE	4.850	Up-regulation
STE_STE20_MST_STK4_ST	O43524	FOXO3	Q13043	STK4	T228	R222L	222	Missense	distal	-6	no	4.912	4.935	EPSD	ICGC;COSMIC	4.850	Up-regulation
STE_STE20_MST_STK4_ST	O43524	FOXO3	Q13043	STK4	S231	I235N	235	Missense	distal	4	no	5.023	5.029	PhosphoSitePlus;EPSD	ICGC	4.850	Up-regulation
STE_STE20_MST_STK4_ST	O43524	FOXO3	Q13043	STK4	S232	I235N	235	Missense	distal	3	no	4.988	4.984	EPSD;PhosphoSitePlus	ICGC	4.850	Down-regulation
STE_STE20_MST_STK4_ST	O43524	FOXO3	Q13043	STK4	S243	R249L	249	Missense	distal	6	no	5.018	5.003	EPSD;PhosphoSitePlus	ICGC;COSMIC	4.850	Down-regulation
STE_STE20_MST_STK4_ST	O43524	FOXO3	Q13043	STK4	S344	D339N	339	Missense	distal	-5	no	4.852	4.880	EPSD	ICGC	4.850	Up-regulation
STE_STE20_MST_STK4_ST	O43524	FOXO3	Q13043	STK4	S344	D339V	339	Missense	distal	-5	no	4.852	4.888	EPSD	ICGC;COSMIC	4.850	Up-regulation
STE_STE20_MST_STK4_ST	O43524	FOXO3	Q13043	STK4	T395	D389N	389	Missense	distal	-6	no	4.928	4.916	EPSD	ICGC;COSMIC	4.850	Down-regulation
STE_STE20_MST_STK4_ST	O43524	FOXO3	Q13043	STK4	T395	D392N	392	Missense	distal	-3	no	4.928	4.931	EPSD	ICGC;COSMIC	4.850	Up-regulation
STE_STE20_MST_STK4_ST	O43524	FOXO3	Q13043	STK4	T395	S399F	399	Missense	distal	4	no	4.928	4.891	EPSD	ICGC	4.850	Down-regulation
STE_STE20_MST_STK4_ST	O43524	FOXO3	Q13043	STK4	S421	P415L	415	Missense	distal	-6	no	4.896	4.886	EPSD	ICGC;COSMIC;GDSC	4.850	Down-regulation
STE_STE20_MST_STK4_ST	O43524	FOXO3	Q13043	STK4	S421	G424S	424	Missense	distal	3	no	4.896	4.894	EPSD	ICGC;COSMIC	4.850	Down-regulation
STE_STE20_MST_STK4_ST	O43524	FOXO3	Q13043	STK4	S421	G420S	420	Missense	proximal	-1	no	4.896	4.894	EPSD	ICGC;COSMIC	4.850	Down-regulation
STE_STE20_MST_STK4_ST	Q14653	IRF3	Q13043	STK4	T3	L9M	9	Missense	distal	6	no	4.959	4.960	EPSD	ICGC;COSMIC	4.850	Up-regulation
STE_STE20_MST_STK4_ST	Q14653	IRF3	Q13043	STK4	S14	L9M	9	Missense	distal	-5	no	4.912	4.910	EPSD	ICGC;COSMIC	4.850	Down-regulation
STE_STE20_MST_STK4_ST	Q96GD4	AURKB	Q13043	STK4	S7	Y8C	8	Missense	proximal	1	no	4.893	4.883	EPSD	ICGC	4.850	Down-regulation
STE_STE20_MST_STK4_ST	Q96GD4	AURKB	Q13043	STK4	S7	P9H	9	Missense	proximal	2	no	4.893	4.923	EPSD	ICGC;COSMIC	4.850	Up-regulation
STE_STE20_MST_STK4_ST	Q96GD4	AURKB	Q13043	STK4	S7	A2S	2	Missense	distal	-5	no	4.893	4.863	EPSD	ICGC;COSMIC	4.850	Down-regulation
STE_STE20_MST_STK4_ST	Q96GD4	AURKB	Q13043	STK4	S22	A17V	17	Missense	distal	-5	no	4.841	4.864	EPSD	ICGC	4.850	Gain
STE_STE20_MST_STK4_ST	P17301	ITGA2	Q13043	STK4	S601	R597L	597	Missense	distal	-4	no	4.924	4.925	EPSD	ICGC	4.850	Up-regulation
STE_STE20_MST_STK4_ST	P17301	ITGA2	Q13043	STK4	S601	D608N	608	Missense	distal	7	no	4.924	4.909	EPSD	ICGC;COSMIC	4.850	Down-regulation
STE_STE20_MST_STK4_ST	P17301	ITGA2	Q13043	STK4	S601	R597S	597	Missense	distal	-4	no	4.924	4.925	EPSD	ICGC;COSMIC	4.850	Up-regulation
STE_STE20_MST_STK4_ST	P17301	ITGA2	Q13043	STK4	S1036	S1039N	1039	Missense	distal	3	no	4.901	4.885	EPSD	ICGC;COSMIC	4.850	Down-regulation
STE_STE20_MST_STK4_ST	P17301	ITGA2	Q13043	STK4	S1036	S1036Y	1036	Missense	central	0	yes	4.901	0.000	EPSD	ICGC	4.850	Loss
STE_STE20_MST_STK4_ST	Q15208	STK38	Q13043	STK4	T4	T4K	4	Missense	central	0	yes	4.997	0.000	EPSD	ICGC;COSMIC	4.850	Loss
STE_STE20_MST_STK4_ST	Q15208	STK38	Q13043	STK4	S6	T4K	4	Missense	proximal	-2	no	4.955	4.972	EPSD	ICGC;COSMIC	4.850	Up-regulation
STE_STE20_MST_STK4_ST	Q15208	STK38	Q13043	STK4	T7	T4K	4	Missense	distal	-3	no	4.959	4.966	EPSD	ICGC;COSMIC	4.850	Up-regulation
STE_STE20_MST_STK4_ST	Q15208	STK38	Q13043	STK4	T21	T21K	21	Missense	central	0	yes	4.934	0.000	EPSD	ICGC	4.850	Loss
STE_STE20_MST_STK4_ST	Q15208	STK38	Q13043	STK4	T23	T21K	21	Missense	proximal	-2	no	4.892	4.909	EPSD	ICGC	4.850	Up-regulation
STE_STE20_MST_STK4_ST	Q15208	STK38	Q13043	STK4	T26	T21K	21	Missense	distal	-5	no	4.858	4.882	EPSD	ICGC	4.850	Up-regulation
STE_STE20_MST_STK4_ST	Q15208	STK38	Q13043	STK4	S252	Y246H	246	Missense	distal	-6	no	4.928	4.924	EPSD	ICGC	4.850	Down-regulation
STE_STE20_MST_STK4_ST	Q15208	STK38	Q13043	STK4	T258	Q260H	260	Missense	proximal	2	no	4.832	4.851	EPSD	ICGC;COSMIC	4.850	Gain
Other_MOS_MOS_ST	P08670	VIM	P00540	MOS	S29	P24L	24	Missense	distal	-5	no	2.419	2.327	EPSD	ICGC;COSMIC	2.415	Loss
Other_MOS_MOS_ST	P08670	VIM	P00540	MOS	S29	V31A	31	Missense	proximal	2	no	2.419	2.411	EPSD	ICGC	2.415	Loss
Other_MOS_MOS_ST	P08670	VIM	P00540	MOS	S29	R36S	36	Missense	distal	7	no	2.419	2.306	EPSD	ICGC;COSMIC	2.415	Loss
Other_MOS_MOS_ST	P08670	VIM	P00540	MOS	T458	D463N	463	Missense	distal	5	no	2.469	2.408	EPSD;PhosphoSitePlus	ICGC;COSMIC	2.415	Loss
Other_MOS_MOS_ST	P08670	VIM	P00540	MOS	T458	D451Y	451	Missense	distal	-7	no	2.469	2.483	EPSD;PhosphoSitePlus	ICGC;COSMIC	2.415	Up-regulation
Other_MOS_MOS_ST	P08670	VIM	P00540	MOS	T458	S459C	459	Missense	proximal	1	no	2.469	2.587	EPSD;PhosphoSitePlus	ICGC;COSMIC	2.415	Up-regulation
Other_MOS_MOS_ST	P08670	VIM	P00540	MOS	S459	D463N	463	Missense	distal	4	no	2.783	2.638	PhosphoSitePlus;EPSD	ICGC;COSMIC	2.415	Down-regulation
Other_MOS_MOS_ST	P08670	VIM	P00540	MOS	S459	S459C	459	Missense	central	0	yes	2.783	0.000	PhosphoSitePlus;EPSD	ICGC;COSMIC	2.415	Loss
STE_STE20_KHS_MAP4K3_ST	Q04759	PRKCQ	Q8IVH8	MAP4K3	S297	R302H	302	Missense	distal	5	no	3.094	3.023	EPSD	ICGC;COSMIC	2.839	Down-regulation
STE_STE20_KHS_MAP4K3_ST	Q04759	PRKCQ	Q8IVH8	MAP4K3	S297	S297R	297	Missense	central	0	yes	3.094	0.000	EPSD	ICGC	2.839	Loss
STE_STE20_KHS_MAP4K3_ST	Q04759	PRKCQ	Q8IVH8	MAP4K3	S297	Q299K	299	Missense	proximal	2	no	3.094	3.155	EPSD	ICGC;COSMIC	2.839	Up-regulation
STE_STE20_KHS_MAP4K3_ST	P19484	TFEB	Q8IVH8	MAP4K3	S3	R8H	8	Missense	distal	5	no	8.626	8.555	PhosphoSitePlus	ICGC;COSMIC;CCLE	2.839	Down-regulation
STE_STE20_KHS_MAP4K3_ST	P19484	TFEB	Q8IVH8	MAP4K3	S3	R4S	4	Missense	proximal	1	no	8.626	8.611	PhosphoSitePlus	ICGC;COSMIC	2.839	Down-regulation
STE_STE20_KHS_MAP4K3_ST	P19484	TFEB	Q8IVH8	MAP4K3	S133	V130M	130	Missense	distal	-3	no	2.928	2.922	EPSD	ICGC;COSMIC;GDSC	2.839	Down-regulation
STE_STE20_KHS_MAP4K3_ST	P19484	TFEB	Q8IVH8	MAP4K3	S133	H129N	129	Missense	distal	-4	no	2.928	2.941	EPSD	ICGC	2.839	Up-regulation
STE_STE20_KHS_MAP4K3_ST	P19484	TFEB	Q8IVH8	MAP4K3	S133	S133F	133	Missense	central	0	yes	2.928	0.000	EPSD	ICGC	2.839	Loss
STE_STE20_KHS_MAP4K3_ST	Q8IVH8	MAP4K3	Q8IVH8	MAP4K3	T145	N141K	141	Missense	distal	-4	no	2.899	2.909	EPSD	ICGC	2.839	Up-regulation
STE_STE20_KHS_MAP4K3_ST	Q8IVH8	MAP4K3	Q8IVH8	MAP4K3	T145	T145M	145	Missense	central	0	yes	2.899	0.000	EPSD	ICGC;COSMIC	2.839	Loss
STE_STE20_KHS_MAP4K3_ST	Q8IVH8	MAP4K3	Q8IVH8	MAP4K3	S170	W177L	177	Missense	distal	7	no	10.328	10.291	PhosphoSitePlus	ICGC;COSMIC	2.839	Down-regulation
STE_STE20_KHS_MAP4K3_ST	Q8IVH8	MAP4K3	Q8IVH8	MAP4K3	S170	P175Q	175	Missense	distal	5	no	10.328	10.248	PhosphoSitePlus	ICGC;COSMIC	2.839	Down-regulation
STE_STE20_KHS_MAP4K3_ST	Q8IVH8	MAP4K3	Q8IVH8	MAP4K3	S170	T164P	164	Missense	distal	-6	no	10.328	10.242	PhosphoSitePlus	ICGC	2.839	Down-regulation
PKL_FJ_FAM20C_ST	Q9GZV9	FGF23	Q8IXL6	FAM20C	S180	E186Q	186	Missense	distal	6	no	6.631	6.581	PhosphoSitePlus	ICGC;COSMIC	2.180	Down-regulation
PKL_FJ_FAM20C_ST	Q9GZV9	FGF23	Q8IXL6	FAM20C	S180	E182K	182	Missense	proximal	2	no	6.631	6.569	PhosphoSitePlus	ICGC;COSMIC	2.180	Down-regulation
PKL_FJ_FAM20C_ST	Q9GZV9	FGF23	Q8IXL6	FAM20C	S180	E186G	186	Missense	distal	6	no	6.631	6.538	PhosphoSitePlus	ICGC;COSMIC	2.180	Down-regulation
PKL_FJ_FAM20C_ST	Q9GZV9	FGF23	Q8IXL6	FAM20C	S180	R175W	175	Missense	distal	-5	no	6.631	6.592	PhosphoSitePlus	ICGC;GDSC;CCLE	2.180	Down-regulation
PKL_FJ_FAM20C_ST	Q9GZV9	FGF23	Q8IXL6	FAM20C	S180	R176W	176	Missense	distal	-4	no	6.631	6.581	PhosphoSitePlus	ICGC;COSMIC	2.180	Down-regulation
PKL_FJ_FAM20C_ST	Q9GZV9	FGF23	Q8IXL6	FAM20C	S180	R187Q	187	Missense	distal	7	no	6.631	6.524	PhosphoSitePlus	ICGC	2.180	Down-regulation
PKL_FJ_FAM20C_ST	Q9GZV9	FGF23	Q8IXL6	FAM20C	S180	T178I	178	Missense	proximal	-2	no	6.631	6.628	PhosphoSitePlus	ICGC;COSMIC	2.180	Down-regulation
PKL_FJ_FAM20C_ST	P23327	HRC	Q8IXL6	FAM20C	S96	S96A	96	Missense	central	0	yes	6.169	0.000	PhosphoSitePlus	ICGC;COSMIC	2.180	Loss
PKL_FJ_FAM20C_ST	P23327	HRC	Q8IXL6	FAM20C	S96	E91Q	91	Missense	distal	-5	no	6.169	6.119	PhosphoSitePlus	ICGC	2.180	Down-regulation
PKL_FJ_FAM20C_ST	P23327	HRC	Q8IXL6	FAM20C	S263	S263Y	263	Missense	central	0	yes	2.405	0.000	EPSD	ICGC	2.180	Loss
PKL_FJ_FAM20C_ST	P23327	HRC	Q8IXL6	FAM20C	S501	D499N	499	Missense	proximal	-2	no	2.419	2.463	EPSD	ICGC;COSMIC	2.180	Up-regulation
TK_Eph_EPHA4_Y	P54764	EPHA4	P54764	EPHA4	Y596	V597A	597	Missense	proximal	1	no	4.449	4.417	EPSD;PhosphoSitePlus	ICGC;COSMIC	1.226	Down-regulation
TK_Eph_EPHA4_Y	P54764	EPHA4	P54764	EPHA4	Y596	T595K	595	Missense	proximal	-1	no	4.449	3.699	EPSD;PhosphoSitePlus	ICGC;COSMIC	1.226	Down-regulation
TK_Eph_EPHA4_Y	P54764	EPHA4	P54764	EPHA4	Y596	T601K	601	Missense	distal	5	no	4.449	4.599	EPSD;PhosphoSitePlus	ICGC	1.226	Up-regulation
TK_Eph_EPHA4_Y	P54764	EPHA4	P54764	EPHA4	Y596	D598N	598	Missense	proximal	2	no	4.449	3.483	EPSD;PhosphoSitePlus	ICGC	1.226	Down-regulation
TK_Eph_EPHA4_Y	P54764	EPHA4	P54764	EPHA4	Y602	V597A	597	Missense	distal	-5	no	4.080	4.069	PhosphoSitePlus;EPSD	ICGC;COSMIC	1.226	Down-regulation
TK_Eph_EPHA4_Y	P54764	EPHA4	P54764	EPHA4	Y602	D604G	604	Missense	proximal	2	no	4.080	2.922	PhosphoSitePlus;EPSD	ICGC;COSMIC	1.226	Down-regulation
TK_Eph_EPHA4_Y	P54764	EPHA4	P54764	EPHA4	Y602	T595K	595	Missense	distal	-7	no	4.080	4.152	PhosphoSitePlus;EPSD	ICGC;COSMIC	1.226	Up-regulation
TK_Eph_EPHA4_Y	P54764	EPHA4	P54764	EPHA4	Y602	T601K	601	Missense	proximal	-1	no	4.080	3.330	PhosphoSitePlus;EPSD	ICGC	1.226	Down-regulation
TK_Eph_EPHA4_Y	P54764	EPHA4	P54764	EPHA4	Y602	N606K	606	Missense	distal	4	no	4.080	4.088	PhosphoSitePlus;EPSD	ICGC	1.226	Up-regulation
TK_Eph_EPHA4_Y	P54764	EPHA4	P54764	EPHA4	Y602	V609L	609	Missense	distal	7	no	4.080	4.126	PhosphoSitePlus;EPSD	ICGC	1.226	Up-regulation
TK_Eph_EPHA4_Y	P54764	EPHA4	P54764	EPHA4	Y602	D598N	598	Missense	distal	-4	no	4.080	4.076	PhosphoSitePlus;EPSD	ICGC	1.226	Down-regulation
TK_Eph_EPHA4_Y	P54764	EPHA4	P54764	EPHA4	Y779	A777P	777	Missense	proximal	-2	no	4.985	5.055	EPSD	ICGC	1.226	Up-regulation
TK_Eph_EPHA4_Y	P54764	EPHA4	P54764	EPHA4	Y779	P775Q	775	Missense	distal	-4	no	4.985	4.974	EPSD	ICGC	1.226	Down-regulation
TK_Eph_EPHA4_Y	P54764	EPHA4	P54764	EPHA4	Y779	A777E	777	Missense	proximal	-2	no	4.985	4.648	EPSD	ICGC	1.226	Down-regulation
TK_Eph_EPHA4_Y	P54764	EPHA4	P54764	EPHA4	Y779	R782S	782	Missense	distal	3	no	4.985	4.900	EPSD	ICGC;COSMIC	1.226	Down-regulation
CMGC_MAPK_ERK3_MAPK6_ST	Q9Y6Q9	NCOA3	Q16659	MAPK6	S32	R36Q	36	Missense	distal	4	no	2.473	2.525	EPSD	ICGC;COSMIC	2.026	Up-regulation
CMGC_MAPK_ERK3_MAPK6_ST	Q9Y6Q9	NCOA3	Q16659	MAPK6	S543	L548W	548	Missense	distal	5	no	2.188	2.229	EPSD	ICGC;COSMIC	2.026	Up-regulation
CMGC_MAPK_ERK3_MAPK6_ST	Q9Y6Q9	NCOA3	Q16659	MAPK6	S615	L613F	613	Missense	proximal	-2	no	2.468	1.982	EPSD	ICGC;COSMIC	2.026	Loss
CMGC_MAPK_ERK3_MAPK6_ST	Q9Y6Q9	NCOA3	Q16659	MAPK6	S636	S635F	635	Missense	proximal	-1	no	3.160	3.080	EPSD	ICGC	2.026	Down-regulation
CMGC_MAPK_ERK3_MAPK6_ST	Q9Y6Q9	NCOA3	Q16659	MAPK6	S640	S635F	635	Missense	distal	-5	no	2.062	2.030	EPSD	ICGC	2.026	Down-regulation
CMGC_MAPK_ERK3_MAPK6_ST	Q9Y6Q9	NCOA3	Q16659	MAPK6	T706	I713V	713	Missense	distal	7	no	2.380	2.385	EPSD	ICGC;COSMIC	2.026	Up-regulation
CMGC_MAPK_ERK3_MAPK6_ST	Q9Y6Q9	NCOA3	Q16659	MAPK6	S1033	S1033Y	1033	Missense	central	0	yes	2.731	0.000	EPSD	ICGC;COSMIC	2.026	Loss
CMGC_MAPK_ERK3_MAPK6_ST	O95551	TDP2	Q16659	MAPK6	S60	F62L	62	Missense	proximal	2	no	6.710	6.775	PhosphoSitePlus	ICGC	2.026	Up-regulation
CMGC_MAPK_ERK3_MAPK6_ST	O95551	TDP2	Q16659	MAPK6	S60	L58V	58	Missense	proximal	-2	no	6.710	6.612	PhosphoSitePlus	ICGC	2.026	Down-regulation
CMGC_MAPK_ERK3_MAPK6_ST	O95551	TDP2	Q16659	MAPK6	T88	D86G	86	Missense	proximal	-2	no	1.735	2.383	EPSD	ICGC	2.026	Gain
CMGC_MAPK_ERK3_MAPK6_ST	O95551	TDP2	Q16659	MAPK6	T92	V85I	85	Missense	distal	-7	no	2.827	2.782	EPSD	ICGC	2.026	Down-regulation
CMGC_MAPK_ERK3_MAPK6_ST	O95551	TDP2	Q16659	MAPK6	T92	D86G	86	Missense	distal	-6	no	2.827	2.846	EPSD	ICGC	2.026	Up-regulation
CMGC_MAPK_ERK3_MAPK6_ST	O95551	TDP2	Q16659	MAPK6	T92	N89S	89	Missense	distal	-3	no	2.827	2.823	EPSD	ICGC	2.026	Down-regulation
CAMK_CAMK2_CAMK2G_ST	Q13555	CAMK2G	Q13555	CAMK2G	S36	A41T	41	Missense	distal	5	no	3.968	4.107	EPSD	ICGC;COSMIC;GDSC;CCLE	2.962	Up-regulation
CAMK_CAMK2_CAMK2G_ST	Q13555	CAMK2G	Q13555	CAMK2G	T37	A41T	41	Missense	distal	4	no	3.002	3.008	EPSD	ICGC;COSMIC;GDSC;CCLE	2.962	Up-regulation
CAMK_CAMK2_CAMK2G_ST	Q13555	CAMK2G	Q13555	CAMK2G	S280	T277M	277	Missense	distal	-3	no	6.076	5.209	EPSD;PhosphoSitePlus	ICGC;COSMIC	2.962	Down-regulation
CAMK_CAMK2_CAMK2G_ST	Q13555	CAMK2G	Q13555	CAMK2G	S319	F314C	314	Missense	distal	-5	no	7.009	7.044	PhosphoSitePlus;EPSD	ICGC	2.962	Up-regulation
CAMK_CAMK2_CAMK2G_ST	Q13555	CAMK2G	Q13555	CAMK2G	S335	H339R	339	Missense	distal	4	no	4.110	4.161	EPSD	ICGC;COSMIC	2.962	Up-regulation
CAMK_CAMK2_CAMK2G_ST	Q13555	CAMK2G	Q13555	CAMK2G	S335	K333E	333	Missense	proximal	-2	no	4.110	4.114	EPSD	ICGC	2.962	Up-regulation
CAMK_CAMK2_CAMK2G_ST	Q13555	CAMK2G	Q13555	CAMK2G	S336	H339R	339	Missense	distal	3	no	3.041	2.927	EPSD	ICGC;COSMIC	2.962	Loss
CAMK_CAMK2_CAMK2G_ST	Q13555	CAMK2G	Q13555	CAMK2G	S336	K333E	333	Missense	distal	-3	no	3.041	2.001	EPSD	ICGC	2.962	Loss
CAMK_CAMK2_CAMK2G_ST	P98082	DAB2	Q13555	CAMK2G	S262	G259R	259	Missense	distal	-3	no	2.347	3.715	EPSD	ICGC;COSMIC	2.962	Gain
CAMK_CAMK2_CAMK2G_ST	P98082	DAB2	Q13555	CAMK2G	S310	Q305P	305	Missense	distal	-5	no	3.389	3.454	EPSD	ICGC;COSMIC	2.962	Up-regulation
CAMK_CAMK2_CAMK2G_ST	P98082	DAB2	Q13555	CAMK2G	S310	S310L	310	Missense	central	0	yes	3.389	0.000	EPSD	ICGC;COSMIC;GDSC;CCLE	2.962	Loss
CAMK_CAMK2_CAMK2G_ST	P98082	DAB2	Q13555	CAMK2G	S310	Q305E	305	Missense	distal	-5	no	3.389	3.527	EPSD	ICGC;COSMIC	2.962	Up-regulation
CAMK_CAMK2_CAMK2G_ST	P98082	DAB2	Q13555	CAMK2G	S313	S310L	310	Missense	distal	-3	no	3.278	4.101	EPSD	ICGC;COSMIC;GDSC;CCLE	2.962	Up-regulation
CAMK_CAMK2_CAMK2G_ST	P98082	DAB2	Q13555	CAMK2G	T371	A374T	374	Missense	distal	3	no	2.898	2.964	EPSD	ICGC	2.962	Gain
CAMK_CAMK2_CAMK2G_ST	P98082	DAB2	Q13555	CAMK2G	S471	P476R	476	Missense	distal	5	no	2.454	3.419	EPSD	ICGC	2.962	Gain
CAMK_CAMK2_CAMK2G_ST	Q16625	OCLN	Q13555	CAMK2G	S159	A152T	152	Missense	distal	-7	no	3.044	3.371	EPSD	ICGC	2.962	Up-regulation
CAMK_CAMK2_CAMK2G_ST	O95180	CACNA1H	Q13555	CAMK2G	S475	R469S	469	Missense	distal	-6	no	3.189	3.060	EPSD	ICGC;COSMIC	2.962	Down-regulation
CAMK_CAMK2_CAMK2G_ST	O95180	CACNA1H	Q13555	CAMK2G	S475	R473W	473	Missense	proximal	-2	no	3.189	3.103	EPSD	ICGC;COSMIC;GDSC;CCLE	2.962	Down-regulation
CAMK_CAMK2_CAMK2G_ST	O95180	CACNA1H	Q13555	CAMK2G	S475	R473Q	473	Missense	proximal	-2	no	3.189	3.163	EPSD	ICGC;COSMIC	2.962	Down-regulation
CAMK_CAMK2_CAMK2G_ST	O95180	CACNA1H	Q13555	CAMK2G	S475	A480T	480	Missense	distal	5	no	3.189	3.329	EPSD	ICGC;COSMIC	2.962	Up-regulation
CAMK_CAMK2_CAMK2G_ST	O95180	CACNA1H	Q13555	CAMK2G	S475	L478I	478	Missense	distal	3	no	3.189	3.071	EPSD	ICGC	2.962	Down-regulation
CAMK_CAMK2_CAMK2G_ST	O95180	CACNA1H	Q13555	CAMK2G	S484	K489N	489	Missense	distal	5	no	3.793	3.224	EPSD	ICGC;COSMIC	2.962	Down-regulation
CAMK_CAMK2_CAMK2G_ST	O95180	CACNA1H	Q13555	CAMK2G	S484	A480T	480	Missense	distal	-4	no	3.793	3.767	EPSD	ICGC;COSMIC	2.962	Down-regulation
CAMK_CAMK2_CAMK2G_ST	O95180	CACNA1H	Q13555	CAMK2G	S484	L478I	478	Missense	distal	-6	no	3.793	3.933	EPSD	ICGC	2.962	Up-regulation
CAMK_CAMK2_CAMK2G_ST	O95180	CACNA1H	Q13555	CAMK2G	S558	A555T	555	Missense	distal	-3	no	3.040	3.517	EPSD	ICGC;COSMIC	2.962	Up-regulation
CAMK_CAMK2_CAMK2G_ST	O95180	CACNA1H	Q13555	CAMK2G	S558	R552Q	552	Missense	distal	-6	no	3.040	3.124	EPSD	ICGC;COSMIC	2.962	Up-regulation
CAMK_CAMK2_CAMK2G_ST	O95180	CACNA1H	Q13555	CAMK2G	S1107	P1113L	1113	Missense	distal	6	no	3.048	2.747	EPSD	ICGC;COSMIC	2.962	Loss
CAMK_CAMK2_CAMK2G_ST	O95180	CACNA1H	Q13555	CAMK2G	S1144	A1137T	1137	Missense	distal	-7	no	3.703	4.030	EPSD	ICGC;CCLE	2.962	Up-regulation
CAMK_CAMK2_CAMK2G_ST	O95180	CACNA1H	Q13555	CAMK2G	S1144	R1141Q	1141	Missense	distal	-3	no	3.703	2.550	EPSD	ICGC;COSMIC	2.962	Loss
CAMK_CAMK2_CAMK2G_ST	O95180	CACNA1H	Q13555	CAMK2G	S1144	A1151V	1151	Missense	distal	7	no	3.703	3.704	EPSD	ICGC	2.962	Up-regulation
CAMK_CAMK2_CAMK2G_ST	O95180	CACNA1H	Q13555	CAMK2G	S1144	S1140G	1140	Missense	distal	-4	no	3.703	3.808	EPSD	ICGC;COSMIC	2.962	Up-regulation
CAMK_CAMK2_CAMK2G_ST	O95180	CACNA1H	Q13555	CAMK2G	S1168	L1167V	1167	Missense	proximal	-1	no	3.279	3.478	EPSD	ICGC;COSMIC	2.962	Up-regulation
CAMK_CAMK2_CAMK2G_ST	O95180	CACNA1H	Q13555	CAMK2G	S1168	E1170D	1170	Missense	proximal	2	no	3.279	3.329	EPSD	ICGC;COSMIC	2.962	Up-regulation
CAMK_CAMK2_CAMK2G_ST	O95180	CACNA1H	Q13555	CAMK2G	S1168	G1169D	1169	Missense	proximal	1	no	3.279	3.302	EPSD	ICGC;COSMIC	2.962	Up-regulation
CAMK_CAMK2_CAMK2G_ST	O95180	CACNA1H	Q13555	CAMK2G	T1175	E1170D	1170	Missense	distal	-5	no	3.089	3.158	EPSD	ICGC;COSMIC	2.962	Up-regulation
CAMK_CAMK2_CAMK2G_ST	O95180	CACNA1H	Q13555	CAMK2G	T1175	G1169D	1169	Missense	distal	-6	no	3.089	3.136	EPSD	ICGC;COSMIC	2.962	Up-regulation
CAMK_CAMK2_CAMK2G_ST	O95180	CACNA1H	Q13555	CAMK2G	T1175	D1177N	1177	Missense	proximal	2	no	3.089	3.082	EPSD	ICGC	2.962	Down-regulation
CAMK_CAMK2_CAMK2G_ST	O95180	CACNA1H	Q13555	CAMK2G	T1175	E1178K	1178	Missense	distal	3	no	3.089	3.024	EPSD	ICGC;COSMIC	2.962	Down-regulation
CAMK_CAMK2_CAMK2G_ST	O95180	CACNA1H	Q13555	CAMK2G	T1175	G1182D	1182	Missense	distal	7	no	3.089	3.092	EPSD	ICGC;COSMIC	2.962	Up-regulation
CAMK_CAMK2_CAMK2G_ST	O95180	CACNA1H	Q13555	CAMK2G	T1175	G1182S	1182	Missense	distal	7	no	3.089	3.105	EPSD	ICGC;GDSC;CCLE	2.962	Up-regulation
CAMK_CAMK2_CAMK2G_ST	O95180	CACNA1H	Q13555	CAMK2G	T1175	D1176N	1176	Missense	proximal	1	no	3.089	3.097	EPSD	ICGC	2.962	Up-regulation
CAMK_CAMK2_CAMK2G_ST	O95180	CACNA1H	Q13555	CAMK2G	T1806	G1812E	1812	Missense	distal	6	no	2.948	3.468	EPSD	ICGC	2.962	Gain
CAMK_CAMK2_CAMK2G_ST	O95180	CACNA1H	Q13555	CAMK2G	S1822	R1819C	1819	Missense	distal	-3	no	3.365	1.837	EPSD	ICGC;COSMIC	2.962	Loss
CAMK_CAMK2_CAMK2G_ST	O95180	CACNA1H	Q13555	CAMK2G	S1822	C1828Y	1828	Missense	distal	6	no	3.365	3.439	EPSD	ICGC	2.962	Up-regulation
CAMK_CAMK2_CAMK2G_ST	O95180	CACNA1H	Q13555	CAMK2G	S1905	R1898M	1898	Missense	distal	-7	no	4.809	4.153	EPSD	ICGC	2.962	Down-regulation
CAMK_CAMK2_CAMK2G_ST	O95180	CACNA1H	Q13555	CAMK2G	S1905	A1908T	1908	Missense	distal	3	no	4.809	4.875	EPSD	ICGC	2.962	Up-regulation
CAMK_CAMK2_CAMK2G_ST	O95180	CACNA1H	Q13555	CAMK2G	S1905	S1905I	1905	Missense	central	0	yes	4.809	0.000	EPSD	ICGC;COSMIC	2.962	Loss
CAMK_CAMK2_CAMK2G_ST	O95180	CACNA1H	Q13555	CAMK2G	S2137	V2138M	2138	Missense	proximal	1	no	3.954	3.873	EPSD	ICGC;COSMIC	2.962	Down-regulation
CAMK_CAMK2_CAMK2G_ST	O95180	CACNA1H	Q13555	CAMK2G	S2137	R2133C	2133	Missense	distal	-4	no	3.954	4.084	EPSD	ICGC;COSMIC	2.962	Up-regulation
CAMK_CAMK2_CAMK2G_ST	O95180	CACNA1H	Q13555	CAMK2G	S2137	R2134K	2134	Missense	distal	-3	no	3.954	3.584	EPSD	ICGC	2.962	Down-regulation
Atypical_PDHK_PDHK_PDK1_ST	P29803	PDHA2	Q15118	PDK1	S291	R286C	286	Missense	distal	-5	no	0.357	0.352	EPSD;PhosphoSitePlus	ICGC;COSMIC	0.124	Down-regulation
Atypical_PDHK_PDHK_PDK1_ST	P29803	PDHA2	Q15118	PDK1	S291	R286S	286	Missense	distal	-5	no	0.357	0.348	EPSD;PhosphoSitePlus	ICGC;COSMIC	0.124	Down-regulation
Atypical_PDHK_PDHK_PDK1_ST	P29803	PDHA2	Q15118	PDK1	S293	R286C	286	Missense	distal	-7	no	0.147	0.146	EPSD	ICGC;COSMIC	0.124	Down-regulation
CMGC_MAPK_JNK_MAPK8_ST	Q96EB6	SIRT1	P45983	MAPK8	S14	A18G	18	Missense	distal	4	no	7.514	7.171	EPSD	ICGC	2.638	Down-regulation
CMGC_MAPK_JNK_MAPK8_ST	Q96EB6	SIRT1	P45983	MAPK8	S14	S16P	16	Missense	proximal	2	no	7.514	7.329	EPSD	ICGC	2.638	Down-regulation
CMGC_MAPK_JNK_MAPK8_ST	Q96EB6	SIRT1	P45983	MAPK8	S26	S27P	27	Missense	proximal	1	no	-0.608	7.121	EPSD	ICGC	2.638	Gain
CMGC_MAPK_JNK_MAPK8_ST	Q96EB6	SIRT1	P45983	MAPK8	S27	S27F	27	Missense	central	0	yes	10.271	0.000	EPSD;PhosphoSitePlus	ICGC;COSMIC	2.638	Loss
CMGC_MAPK_JNK_MAPK8_ST	Q96EB6	SIRT1	P45983	MAPK8	S27	P28S	28	Missense	proximal	1	no	10.271	2.543	EPSD;PhosphoSitePlus	ICGC;COSMIC	2.638	Loss
CMGC_MAPK_JNK_MAPK8_ST	Q96EB6	SIRT1	P45983	MAPK8	S27	S27P	27	Missense	central	0	yes	10.271	0.000	EPSD;PhosphoSitePlus	ICGC	2.638	Loss
CMGC_MAPK_JNK_MAPK8_ST	Q96EB6	SIRT1	P45983	MAPK8	S47	G53W	53	Missense	distal	6	no	6.651	6.638	PhosphoSitePlus;EPSD	ICGC	2.638	Down-regulation
CMGC_MAPK_JNK_MAPK8_ST	Q96EB6	SIRT1	P45983	MAPK8	S47	R46C	46	Missense	proximal	-1	no	6.651	6.657	PhosphoSitePlus;EPSD	ICGC;COSMIC	2.638	Up-regulation
CMGC_MAPK_JNK_MAPK8_ST	Q96EB6	SIRT1	P45983	MAPK8	S47	R46H	46	Missense	proximal	-1	no	6.651	6.656	PhosphoSitePlus;EPSD	ICGC;COSMIC	2.638	Up-regulation
CMGC_MAPK_JNK_MAPK8_ST	Q96EB6	SIRT1	P45983	MAPK8	S47	P51L	51	Missense	distal	4	no	6.651	6.244	PhosphoSitePlus;EPSD	ICGC;COSMIC	2.638	Down-regulation
CMGC_MAPK_JNK_MAPK8_ST	Q96EB6	SIRT1	P45983	MAPK8	S47	R46S	46	Missense	proximal	-1	no	6.651	6.676	PhosphoSitePlus;EPSD	ICGC;COSMIC	2.638	Up-regulation
CMGC_MAPK_JNK_MAPK8_ST	P46937	YAP1	P45983	MAPK8	T119	V123F	123	Missense	distal	4	no	8.541	8.602	EPSD	ICGC	2.638	Up-regulation
CMGC_MAPK_JNK_MAPK8_ST	P46937	YAP1	P45983	MAPK8	T119	A117S	117	Missense	proximal	-2	no	8.541	8.486	EPSD	ICGC	2.638	Down-regulation
CMGC_MAPK_JNK_MAPK8_ST	P46937	YAP1	P45983	MAPK8	T119	A115T	115	Missense	distal	-4	no	8.541	8.504	EPSD	ICGC	2.638	Down-regulation
CMGC_MAPK_JNK_MAPK8_ST	P46937	YAP1	P45983	MAPK8	T119	H126R	126	Missense	distal	7	no	8.541	8.551	EPSD	ICGC;COSMIC	2.638	Up-regulation
CMGC_MAPK_JNK_MAPK8_ST	P46937	YAP1	P45983	MAPK8	S128	Q133L	133	Missense	distal	5	no	8.498	8.559	EPSD	ICGC;COSMIC	2.638	Up-regulation
CMGC_MAPK_JNK_MAPK8_ST	P46937	YAP1	P45983	MAPK8	S128	V123F	123	Missense	distal	-5	no	8.498	8.442	EPSD	ICGC	2.638	Down-regulation
CMGC_MAPK_JNK_MAPK8_ST	P46937	YAP1	P45983	MAPK8	S128	L134F	134	Missense	distal	6	no	8.498	8.500	EPSD	ICGC;COSMIC	2.638	Up-regulation
CMGC_MAPK_JNK_MAPK8_ST	P46937	YAP1	P45983	MAPK8	S138	Q133L	133	Missense	distal	-5	no	7.515	7.898	EPSD	ICGC;COSMIC	2.638	Up-regulation
CMGC_MAPK_JNK_MAPK8_ST	P46937	YAP1	P45983	MAPK8	S138	V137F	137	Missense	proximal	-1	no	7.515	7.519	EPSD	ICGC;COSMIC	2.638	Up-regulation
CMGC_MAPK_JNK_MAPK8_ST	P46937	YAP1	P45983	MAPK8	S138	T145N	145	Missense	distal	7	no	7.515	7.576	EPSD	ICGC	2.638	Up-regulation
CMGC_MAPK_JNK_MAPK8_ST	P46937	YAP1	P45983	MAPK8	S138	L134F	134	Missense	distal	-4	no	7.515	7.568	EPSD	ICGC;COSMIC	2.638	Up-regulation
CMGC_MAPK_JNK_MAPK8_ST	P46937	YAP1	P45983	MAPK8	T143	V137F	137	Missense	distal	-6	no	6.792	6.768	EPSD	ICGC;COSMIC	2.638	Down-regulation
CMGC_MAPK_JNK_MAPK8_ST	P46937	YAP1	P45983	MAPK8	T143	T145N	145	Missense	proximal	2	no	6.792	6.527	EPSD	ICGC	2.638	Down-regulation
CMGC_MAPK_JNK_MAPK8_ST	P46937	YAP1	P45983	MAPK8	T154	R161L	161	Missense	distal	7	no	7.506	7.521	PhosphoSitePlus;EPSD	ICGC	2.638	Up-regulation
CMGC_MAPK_JNK_MAPK8_ST	P46937	YAP1	P45983	MAPK8	S367	Q372R	372	Missense	distal	5	no	6.322	6.373	EPSD	ICGC;COSMIC	2.638	Up-regulation
CMGC_MAPK_JNK_MAPK8_ST	P46937	YAP1	P45983	MAPK8	S367	G369W	369	Missense	proximal	2	no	6.322	6.210	EPSD	ICGC;COSMIC	2.638	Down-regulation
CMGC_MAPK_JNK_MAPK8_ST	P46937	YAP1	P45983	MAPK8	S367	Q372K	372	Missense	distal	5	no	6.322	6.282	EPSD	ICGC;COSMIC	2.638	Down-regulation
CMGC_MAPK_JNK_MAPK8_ST	P46937	YAP1	P45983	MAPK8	S397	T398A	398	Missense	proximal	1	no	2.367	3.007	EPSD	ICGC;COSMIC	2.638	Gain
CMGC_MAPK_JNK_MAPK8_ST	P46937	YAP1	P45983	MAPK8	S400	L402P	402	Missense	proximal	2	no	2.744	2.821	EPSD	ICGC;COSMIC	2.638	Up-regulation
CMGC_MAPK_JNK_MAPK8_ST	P46937	YAP1	P45983	MAPK8	S400	R394Q	394	Missense	distal	-6	no	2.744	2.642	EPSD	ICGC;COSMIC	2.638	Down-regulation
CMGC_MAPK_JNK_MAPK8_ST	P46937	YAP1	P45983	MAPK8	S400	S397I	397	Missense	distal	-3	no	2.744	2.584	EPSD	ICGC	2.638	Loss
CMGC_MAPK_JNK_MAPK8_ST	P46937	YAP1	P45983	MAPK8	S400	T398A	398	Missense	proximal	-2	no	2.744	2.773	EPSD	ICGC;COSMIC	2.638	Up-regulation
CMGC_MAPK_JNK_MAPK8_ST	P46937	YAP1	P45983	MAPK8	S406	L402P	402	Missense	distal	-4	no	2.553	2.880	EPSD	ICGC;COSMIC	2.638	Gain
CMGC_MAPK_JNK_MAPK8_ST	P46937	YAP1	P45983	MAPK8	T412	V409F	409	Missense	distal	-3	no	7.555	7.575	EPSD	ICGC	2.638	Up-regulation
CMGC_MAPK_JNK_MAPK8_ST	P36956	SREBF1	P45983	MAPK8	S63	S63F	63	Missense	central	0	yes	9.118	0.000	EPSD	ICGC;COSMIC	2.638	Loss
CMGC_MAPK_JNK_MAPK8_ST	P36956	SREBF1	P45983	MAPK8	S63	G58D	58	Missense	distal	-5	no	9.118	8.966	EPSD	ICGC;COSMIC	2.638	Down-regulation
CMGC_MAPK_JNK_MAPK8_ST	P36956	SREBF1	P45983	MAPK8	S63	G57R	57	Missense	distal	-6	no	9.118	9.122	EPSD	ICGC;COSMIC	2.638	Up-regulation
CMGC_MAPK_JNK_MAPK8_ST	P36956	SREBF1	P45983	MAPK8	S63	A62D	62	Missense	proximal	-1	no	9.118	9.103	EPSD	ICGC	2.638	Down-regulation
CMGC_MAPK_JNK_MAPK8_ST	P36956	SREBF1	P45983	MAPK8	S63	S68P	68	Missense	distal	5	no	9.118	9.201	EPSD	ICGC;COSMIC	2.638	Up-regulation
CMGC_MAPK_JNK_MAPK8_ST	P36956	SREBF1	P45983	MAPK8	T105	P111T	111	Missense	distal	6	no	5.927	5.949	EPSD	ICGC;COSMIC	2.638	Up-regulation
CMGC_MAPK_JNK_MAPK8_ST	P36956	SREBF1	P45983	MAPK8	T105	P99H	99	Missense	distal	-6	no	5.927	5.971	EPSD	ICGC;COSMIC	2.638	Up-regulation
CMGC_MAPK_JNK_MAPK8_ST	P36956	SREBF1	P45983	MAPK8	T105	P111R	111	Missense	distal	6	no	5.927	5.891	EPSD	ICGC	2.638	Down-regulation
CMGC_MAPK_JNK_MAPK8_ST	P36956	SREBF1	P45983	MAPK8	T105	S112F	112	Missense	distal	7	no	5.927	6.002	EPSD	ICGC	2.638	Up-regulation
CMGC_MAPK_JNK_MAPK8_ST	P36956	SREBF1	P45983	MAPK8	S112	P111T	111	Missense	proximal	-1	no	2.866	2.877	EPSD	ICGC;COSMIC	2.638	Up-regulation
CMGC_MAPK_JNK_MAPK8_ST	P36956	SREBF1	P45983	MAPK8	S112	P111R	111	Missense	proximal	-1	no	2.866	2.851	EPSD	ICGC	2.638	Down-regulation
CMGC_MAPK_JNK_MAPK8_ST	P36956	SREBF1	P45983	MAPK8	S112	S112F	112	Missense	central	0	yes	2.866	0.000	EPSD	ICGC	2.638	Loss
CMGC_MAPK_JNK_MAPK8_ST	P36956	SREBF1	P45983	MAPK8	S112	P114H	114	Missense	proximal	2	no	2.866	2.868	EPSD	ICGC	2.638	Up-regulation
CMGC_MAPK_JNK_MAPK8_ST	P36956	SREBF1	P45983	MAPK8	S112	P118H	118	Missense	distal	6	no	2.866	2.843	EPSD	ICGC;COSMIC	2.638	Down-regulation
CMGC_MAPK_JNK_MAPK8_ST	P36956	SREBF1	P45983	MAPK8	S112	A115T	115	Missense	distal	3	no	2.866	2.876	EPSD	ICGC;COSMIC	2.638	Up-regulation
CMGC_MAPK_JNK_MAPK8_ST	P36956	SREBF1	P45983	MAPK8	S112	S117F	117	Missense	distal	5	no	2.866	2.942	EPSD	ICGC;COSMIC	2.638	Up-regulation
CMGC_MAPK_JNK_MAPK8_ST	P36956	SREBF1	P45983	MAPK8	S117	P111T	111	Missense	distal	-6	no	8.727	8.663	EPSD;PhosphoSitePlus	ICGC;COSMIC	2.638	Down-regulation
CMGC_MAPK_JNK_MAPK8_ST	P36956	SREBF1	P45983	MAPK8	S117	P111R	111	Missense	distal	-6	no	8.727	8.793	EPSD;PhosphoSitePlus	ICGC	2.638	Up-regulation
CMGC_MAPK_JNK_MAPK8_ST	P36956	SREBF1	P45983	MAPK8	S117	S112F	112	Missense	distal	-5	no	8.727	9.196	EPSD;PhosphoSitePlus	ICGC	2.638	Up-regulation
CMGC_MAPK_JNK_MAPK8_ST	P36956	SREBF1	P45983	MAPK8	S117	P114H	114	Missense	distal	-3	no	8.727	8.622	EPSD;PhosphoSitePlus	ICGC	2.638	Down-regulation
CMGC_MAPK_JNK_MAPK8_ST	P36956	SREBF1	P45983	MAPK8	S117	P118H	118	Missense	proximal	1	no	8.727	0.812	EPSD;PhosphoSitePlus	ICGC;COSMIC	2.638	Loss
CMGC_MAPK_JNK_MAPK8_ST	P36956	SREBF1	P45983	MAPK8	S117	A115T	115	Missense	proximal	-2	no	8.727	8.697	EPSD;PhosphoSitePlus	ICGC;COSMIC	2.638	Down-regulation
CMGC_MAPK_JNK_MAPK8_ST	P36956	SREBF1	P45983	MAPK8	S117	P120L	120	Missense	distal	3	no	8.727	8.829	EPSD;PhosphoSitePlus	ICGC;COSMIC	2.638	Up-regulation
CMGC_MAPK_JNK_MAPK8_ST	P36956	SREBF1	P45983	MAPK8	S117	S117F	117	Missense	central	0	yes	8.727	0.000	EPSD;PhosphoSitePlus	ICGC;COSMIC	2.638	Loss
CMGC_MAPK_JNK_MAPK8_ST	P10636	MAPT	P45983	MAPK8	T111	D116E	116	Missense	distal	5	no	7.410	7.353	EPSD	ICGC;COSMIC	2.638	Down-regulation
CMGC_MAPK_JNK_MAPK8_ST	P10636	MAPT	P45983	MAPK8	S228	P233H	233	Missense	distal	5	no	9.293	9.261	EPSD	ICGC;COSMIC	2.638	Down-regulation
CMGC_MAPK_JNK_MAPK8_ST	P10636	MAPT	P45983	MAPK8	S228	S232F	232	Missense	distal	4	no	9.293	8.835	EPSD	ICGC	2.638	Down-regulation
CMGC_MAPK_JNK_MAPK8_ST	P10636	MAPT	P45983	MAPK8	S228	D225N	225	Missense	distal	-3	no	9.293	9.128	EPSD	ICGC	2.638	Down-regulation
CMGC_MAPK_JNK_MAPK8_ST	P10636	MAPT	P45983	MAPK8	S228	V224I	224	Missense	distal	-4	no	9.293	9.685	EPSD	ICGC;COSMIC	2.638	Up-regulation
CMGC_MAPK_JNK_MAPK8_ST	P10636	MAPT	P45983	MAPK8	S232	P233H	233	Missense	proximal	1	no	7.907	-0.008	EPSD	ICGC;COSMIC	2.638	Loss
CMGC_MAPK_JNK_MAPK8_ST	P10636	MAPT	P45983	MAPK8	S232	S232F	232	Missense	central	0	yes	7.907	0.000	EPSD	ICGC	2.638	Loss
CMGC_MAPK_JNK_MAPK8_ST	P10636	MAPT	P45983	MAPK8	S232	D225N	225	Missense	distal	-7	no	7.907	7.913	EPSD	ICGC	2.638	Up-regulation
CMGC_MAPK_JNK_MAPK8_ST	P10636	MAPT	P45983	MAPK8	S232	P239Q	239	Missense	distal	7	no	7.907	7.886	EPSD	ICGC;COSMIC	2.638	Down-regulation
CMGC_MAPK_JNK_MAPK8_ST	P10636	MAPT	P45983	MAPK8	S238	P233H	233	Missense	distal	-5	no	7.548	7.745	EPSD	ICGC;COSMIC	2.638	Up-regulation
CMGC_MAPK_JNK_MAPK8_ST	P10636	MAPT	P45983	MAPK8	S238	S232F	232	Missense	distal	-6	no	7.548	7.729	EPSD	ICGC	2.638	Up-regulation
CMGC_MAPK_JNK_MAPK8_ST	P10636	MAPT	P45983	MAPK8	S238	P239Q	239	Missense	proximal	1	no	7.548	0.439	EPSD	ICGC;COSMIC	2.638	Loss
CMGC_MAPK_JNK_MAPK8_ST	P10636	MAPT	P45983	MAPK8	S428	S427F	427	Missense	proximal	-1	no	7.318	7.289	EPSD	ICGC	2.638	Down-regulation
CMGC_MAPK_JNK_MAPK8_ST	P10636	MAPT	P45983	MAPK8	S438	Y441H	441	Missense	distal	3	no	9.810	9.693	EPSD	ICGC;COSMIC	2.638	Down-regulation
CMGC_MAPK_JNK_MAPK8_ST	P10636	MAPT	P45983	MAPK8	S447	Y441H	441	Missense	distal	-6	no	3.231	3.133	EPSD	ICGC;COSMIC	2.638	Down-regulation
CMGC_MAPK_JNK_MAPK8_ST	P10636	MAPT	P45983	MAPK8	S516	G521R	521	Missense	distal	5	no	8.663	8.666	EPSD	ICGC;COSMIC	2.638	Up-regulation
CMGC_MAPK_JNK_MAPK8_ST	P10636	MAPT	P45983	MAPK8	S519	G521R	521	Missense	proximal	2	no	8.616	8.576	EPSD	ICGC;COSMIC	2.638	Down-regulation
CMGC_MAPK_JNK_MAPK8_ST	P17275	JUNB	P45983	MAPK8	S74	S70A	70	Missense	distal	-4	no	2.706	2.529	EPSD	ICGC;COSMIC	2.638	Loss
CMGC_MAPK_JNK_MAPK8_ST	P17275	JUNB	P45983	MAPK8	S74	G77S	77	Missense	distal	3	no	2.706	2.516	EPSD	ICGC	2.638	Loss
CMGC_MAPK_JNK_MAPK8_ST	P17275	JUNB	P45983	MAPK8	S74	S67T	67	Missense	distal	-7	no	2.706	2.708	EPSD	ICGC	2.638	Up-regulation
CMGC_MAPK_JNK_MAPK8_ST	P17275	JUNB	P45983	MAPK8	T102	Q108H	108	Missense	distal	6	no	8.898	8.865	PhosphoSitePlus;EPSD	ICGC;COSMIC	2.638	Down-regulation
CMGC_MAPK_JNK_MAPK8_ST	P17275	JUNB	P45983	MAPK8	T104	Q108H	108	Missense	distal	4	no	8.622	8.425	EPSD;PhosphoSitePlus	ICGC;COSMIC	2.638	Down-regulation
CMGC_MAPK_JNK_MAPK8_ST	P17275	JUNB	P45983	MAPK8	S237	T238I	238	Missense	proximal	1	no	1.623	2.736	EPSD	ICGC	2.638	Gain
CMGC_MAPK_JNK_MAPK8_ST	P17275	JUNB	P45983	MAPK8	T255	P260L	260	Missense	distal	5	no	7.948	7.947	EPSD	ICGC	2.638	Down-regulation
CMGC_MAPK_JNK_MAPK8_ST	P17275	JUNB	P45983	MAPK8	T255	D253E	253	Missense	proximal	-2	no	7.948	8.002	EPSD	ICGC;COSMIC;CCLE	2.638	Up-regulation
CMGC_MAPK_JNK_MAPK8_ST	P17275	JUNB	P45983	MAPK8	S259	Q266R	266	Missense	distal	7	no	8.416	8.462	EPSD	ICGC;COSMIC	2.638	Up-regulation
CMGC_MAPK_JNK_MAPK8_ST	P17275	JUNB	P45983	MAPK8	S259	P260L	260	Missense	proximal	1	no	8.416	0.843	EPSD	ICGC	2.638	Loss
CMGC_MAPK_JNK_MAPK8_ST	P17275	JUNB	P45983	MAPK8	S259	D253E	253	Missense	distal	-6	no	8.416	8.316	EPSD	ICGC;COSMIC;CCLE	2.638	Down-regulation
CMGC_MAPK_JNK_MAPK8_ST	Q9NRA8	EIF4ENIF1	P45983	MAPK8	S115	D109N	109	Missense	distal	-6	no	7.116	7.199	EPSD	ICGC;COSMIC	2.638	Up-regulation
CMGC_MAPK_JNK_MAPK8_ST	Q9NRA8	EIF4ENIF1	P45983	MAPK8	S115	R119Q	119	Missense	distal	4	no	7.116	7.349	EPSD	ICGC;COSMIC	2.638	Up-regulation
CMGC_MAPK_JNK_MAPK8_ST	Q9NRA8	EIF4ENIF1	P45983	MAPK8	S115	S120R	120	Missense	distal	5	no	7.116	7.188	EPSD	ICGC	2.638	Up-regulation
CMGC_MAPK_JNK_MAPK8_ST	Q9NRA8	EIF4ENIF1	P45983	MAPK8	S115	V112A	112	Missense	distal	-3	no	7.116	7.545	EPSD	ICGC;COSMIC	2.638	Up-regulation
CMGC_MAPK_JNK_MAPK8_ST	Q9NRA8	EIF4ENIF1	P45983	MAPK8	S115	R119W	119	Missense	distal	4	no	7.116	7.088	EPSD	ICGC	2.638	Down-regulation
CMGC_MAPK_JNK_MAPK8_ST	Q9NRA8	EIF4ENIF1	P45983	MAPK8	S133	R134W	134	Missense	proximal	1	no	1.284	2.747	EPSD	ICGC;COSMIC	2.638	Gain
CMGC_MAPK_JNK_MAPK8_ST	Q9NRA8	EIF4ENIF1	P45983	MAPK8	S138	E141Q	141	Missense	distal	3	no	6.232	6.276	EPSD	ICGC;COSMIC	2.638	Up-regulation
CMGC_MAPK_JNK_MAPK8_ST	Q9NRA8	EIF4ENIF1	P45983	MAPK8	S138	D143N	143	Missense	distal	5	no	6.232	6.254	EPSD	ICGC;COSMIC	2.638	Up-regulation
CMGC_MAPK_JNK_MAPK8_ST	Q9NRA8	EIF4ENIF1	P45983	MAPK8	S138	R134W	134	Missense	distal	-4	no	6.232	5.989	EPSD	ICGC;COSMIC	2.638	Down-regulation
CMGC_MAPK_JNK_MAPK8_ST	Q9NRA8	EIF4ENIF1	P45983	MAPK8	S138	P139T	139	Missense	proximal	1	no	6.232	-0.755	EPSD	ICGC;COSMIC	2.638	Loss
CMGC_MAPK_JNK_MAPK8_ST	Q9NRA8	EIF4ENIF1	P45983	MAPK8	S138	S133F	133	Missense	distal	-5	no	6.232	6.701	EPSD	ICGC;COSMIC	2.638	Up-regulation
CMGC_MAPK_JNK_MAPK8_ST	Q9NRA8	EIF4ENIF1	P45983	MAPK8	S301	A295V	295	Missense	distal	-6	no	9.158	9.360	EPSD;PhosphoSitePlus	ICGC	2.638	Up-regulation
CMGC_MAPK_JNK_MAPK8_ST	Q05639	EEF1A2	P45983	MAPK8	T22	S21F	21	Missense	proximal	-1	no	3.146	3.116	EPSD	ICGC	2.638	Down-regulation
CMGC_MAPK_JNK_MAPK8_ST	Q05639	EEF1A2	P45983	MAPK8	T22	V16M	16	Missense	distal	-6	no	3.146	3.106	EPSD	ICGC;COSMIC	2.638	Down-regulation
CMGC_MAPK_JNK_MAPK8_ST	Q05639	EEF1A2	P45983	MAPK8	T133	R134W	134	Missense	proximal	1	no	1.376	2.839	EPSD	ICGC;COSMIC	2.638	Gain
CMGC_MAPK_JNK_MAPK8_ST	Q05639	EEF1A2	P45983	MAPK8	S205	P206A	206	Missense	proximal	1	no	7.665	1.318	EPSD;PhosphoSitePlus	ICGC;COSMIC	2.638	Loss
CMGC_MAPK_JNK_MAPK8_ST	Q05639	EEF1A2	P45983	MAPK8	S205	S205F	205	Missense	central	0	yes	7.665	0.000	EPSD;PhosphoSitePlus	ICGC	2.638	Loss
CMGC_MAPK_JNK_MAPK8_ST	Q05639	EEF1A2	P45983	MAPK8	S205	K212N	212	Missense	distal	7	no	7.665	7.749	EPSD;PhosphoSitePlus	ICGC	2.638	Up-regulation
CMGC_MAPK_JNK_MAPK8_ST	Q9H211	CDT1	P45983	MAPK8	S79	P86S	86	Missense	distal	7	no	9.355	9.317	EPSD	ICGC	2.638	Down-regulation
CMGC_MAPK_JNK_MAPK8_ST	Q9H211	CDT1	P45983	MAPK8	S79	S79I	79	Missense	central	0	yes	9.355	0.000	EPSD	ICGC;COSMIC	2.638	Loss
CMGC_MAPK_JNK_MAPK8_ST	Q9H211	CDT1	P45983	MAPK8	T82	P86S	86	Missense	distal	4	no	8.851	8.876	EPSD	ICGC	2.638	Up-regulation
CMGC_MAPK_JNK_MAPK8_ST	Q9H211	CDT1	P45983	MAPK8	T82	S79I	79	Missense	distal	-3	no	8.851	8.692	EPSD	ICGC;COSMIC	2.638	Down-regulation
CMGC_MAPK_JNK_MAPK8_ST	Q9H211	CDT1	P45983	MAPK8	S93	P94T	94	Missense	proximal	1	no	7.852	0.866	EPSD	ICGC	2.638	Loss
CMGC_MAPK_JNK_MAPK8_ST	Q9H211	CDT1	P45983	MAPK8	S93	P86S	86	Missense	distal	-7	no	7.852	7.846	EPSD	ICGC	2.638	Down-regulation
CMGC_MAPK_JNK_MAPK8_ST	Q9H211	CDT1	P45983	MAPK8	S93	Q96K	96	Missense	distal	3	no	7.852	7.755	EPSD	ICGC;COSMIC	2.638	Down-regulation
CMGC_MAPK_JNK_MAPK8_ST	Q9H211	CDT1	P45983	MAPK8	T102	Q96K	96	Missense	distal	-6	no	7.593	7.528	EPSD	ICGC;COSMIC	2.638	Down-regulation
CMGC_MAPK_JNK_MAPK8_ST	Q9H211	CDT1	P45983	MAPK8	T152	A147S	147	Missense	distal	-5	no	7.438	7.454	EPSD	ICGC	2.638	Up-regulation
CMGC_MAPK_JNK_MAPK8_ST	Q9H211	CDT1	P45983	MAPK8	T213	P214L	214	Missense	proximal	1	no	9.762	2.190	EPSD	ICGC	2.638	Loss
CMGC_MAPK_JNK_MAPK8_ST	Q9H211	CDT1	P45983	MAPK8	S318	K311N	311	Missense	distal	-7	no	8.942	8.960	EPSD	ICGC	2.638	Up-regulation
CMGC_MAPK_JNK_MAPK8_ST	Q9H211	CDT1	P45983	MAPK8	S372	R368H	368	Missense	distal	-4	no	8.781	8.840	EPSD	ICGC	2.638	Up-regulation
CMGC_MAPK_JNK_MAPK8_ST	Q9H211	CDT1	P45983	MAPK8	S372	A378S	378	Missense	distal	6	no	8.781	8.785	EPSD	ICGC	2.638	Up-regulation
CMGC_MAPK_JNK_MAPK8_ST	Q9H211	CDT1	P45983	MAPK8	S391	P389H	389	Missense	proximal	-2	no	7.295	7.111	EPSD;PhosphoSitePlus	ICGC	2.638	Down-regulation
CMGC_MAPK_JNK_MAPK8_ST	Q9H211	CDT1	P45983	MAPK8	S391	P395T	395	Missense	distal	4	no	7.295	7.271	EPSD;PhosphoSitePlus	ICGC;COSMIC	2.638	Down-regulation
CMGC_MAPK_JNK_MAPK8_ST	Q9H211	CDT1	P45983	MAPK8	S394	P389H	389	Missense	distal	-5	no	9.045	9.242	EPSD	ICGC	2.638	Up-regulation
CMGC_MAPK_JNK_MAPK8_ST	Q9H211	CDT1	P45983	MAPK8	S394	P395T	395	Missense	proximal	1	no	9.045	2.058	EPSD	ICGC;COSMIC	2.638	Loss
CMGC_MAPK_JNK_MAPK8_ST	Q9H211	CDT1	P45983	MAPK8	T402	T406P	406	Missense	distal	4	no	8.894	8.918	EPSD;PhosphoSitePlus	ICGC;COSMIC	2.638	Up-regulation
CMGC_MAPK_JNK_MAPK8_ST	Q9H211	CDT1	P45983	MAPK8	T402	P395T	395	Missense	distal	-7	no	8.894	8.890	EPSD;PhosphoSitePlus	ICGC;COSMIC	2.638	Down-regulation
CMGC_MAPK_JNK_MAPK8_ST	Q9H211	CDT1	P45983	MAPK8	T402	A405S	405	Missense	distal	3	no	8.894	8.876	EPSD;PhosphoSitePlus	ICGC	2.638	Down-regulation
CMGC_MAPK_JNK_MAPK8_ST	Q9H211	CDT1	P45983	MAPK8	T406	T406P	406	Missense	central	0	yes	7.981	0.000	EPSD;PhosphoSitePlus	ICGC;COSMIC	2.638	Loss
CMGC_MAPK_JNK_MAPK8_ST	Q9H211	CDT1	P45983	MAPK8	T406	A405S	405	Missense	proximal	-1	no	7.981	7.980	EPSD;PhosphoSitePlus	ICGC	2.638	Down-regulation
CMGC_MAPK_JNK_MAPK8_ST	Q9H211	CDT1	P45983	MAPK8	S411	T406P	406	Missense	distal	-5	no	8.546	8.658	EPSD;PhosphoSitePlus	ICGC;COSMIC	2.638	Up-regulation
CMGC_MAPK_JNK_MAPK8_ST	Q9H211	CDT1	P45983	MAPK8	S411	A405S	405	Missense	distal	-6	no	8.546	8.542	EPSD;PhosphoSitePlus	ICGC	2.638	Down-regulation
CMGC_MAPK_JNK_MAPK8_ST	P15336	ATF2	P45983	MAPK8	S136	E130K	130	Missense	distal	-6	no	8.636	8.631	EPSD	ICGC;COSMIC	2.638	Down-regulation
CMGC_MAPK_JNK_MAPK8_ST	P15336	ATF2	P45983	MAPK8	T325	S321G	321	Missense	distal	-4	no	7.959	7.071	EPSD	ICGC;COSMIC	2.638	Down-regulation
CMGC_MAPK_JNK_MAPK8_ST	P15336	ATF2	P45983	MAPK8	S328	S321G	321	Missense	distal	-7	no	8.292	8.305	EPSD	ICGC;COSMIC	2.638	Up-regulation
CMGC_MAPK_JNK_MAPK8_ST	P15336	ATF2	P45983	MAPK8	T333	S340L	340	Missense	distal	7	no	7.887	7.965	EPSD	ICGC;COSMIC	2.638	Up-regulation
CMGC_MAPK_JNK_MAPK8_ST	P15336	ATF2	P45983	MAPK8	T333	Q337H	337	Missense	distal	4	no	7.887	7.691	EPSD	ICGC;COSMIC	2.638	Down-regulation
CMGC_MAPK_JNK_MAPK8_ST	P01106	MYC	P45983	MAPK8	S71	P72S	72	Missense	proximal	1	no	8.539	0.811	PhosphoSitePlus;EPSD	ICGC;COSMIC;GDSC	2.638	Loss
CMGC_MAPK_JNK_MAPK8_ST	P01106	MYC	P45983	MAPK8	S71	P72A	72	Missense	proximal	1	no	8.539	2.192	PhosphoSitePlus;EPSD	ICGC;COSMIC	2.638	Loss
CMGC_MAPK_JNK_MAPK8_ST	P01106	MYC	P45983	MAPK8	S71	P72L	72	Missense	proximal	1	no	8.539	0.967	PhosphoSitePlus;EPSD	ICGC;COSMIC	2.638	Loss
CMGC_MAPK_JNK_MAPK8_ST	P01106	MYC	P45983	MAPK8	S71	P72T	72	Missense	proximal	1	no	8.539	1.553	PhosphoSitePlus;EPSD	ICGC;COSMIC;GDSC	2.638	Loss
CMGC_MAPK_JNK_MAPK8_ST	P01106	MYC	P45983	MAPK8	T78	P72S	72	Missense	distal	-6	no	6.974	6.885	EPSD	ICGC;COSMIC;GDSC	2.638	Down-regulation
CMGC_MAPK_JNK_MAPK8_ST	P01106	MYC	P45983	MAPK8	T78	P72A	72	Missense	distal	-6	no	6.974	6.888	EPSD	ICGC;COSMIC	2.638	Down-regulation
CMGC_MAPK_JNK_MAPK8_ST	P01106	MYC	P45983	MAPK8	T78	P72L	72	Missense	distal	-6	no	6.974	7.065	EPSD	ICGC;COSMIC	2.638	Up-regulation
CMGC_MAPK_JNK_MAPK8_ST	P01106	MYC	P45983	MAPK8	T78	P72T	72	Missense	distal	-6	no	6.974	6.910	EPSD	ICGC;COSMIC;GDSC	2.638	Down-regulation
CMGC_MAPK_JNK_MAPK8_ST	P05067	APP	P45983	MAPK8	T381	E385Q	385	Missense	distal	4	no	7.538	7.458	EPSD	ICGC;COSMIC	2.638	Down-regulation
CMGC_MAPK_JNK_MAPK8_ST	O43524	FOXO3	P45983	MAPK8	S7	P10T	10	Missense	distal	3	no	8.070	7.972	EPSD	ICGC;COSMIC	2.638	Down-regulation
CMGC_MAPK_JNK_MAPK8_ST	O43524	FOXO3	P45983	MAPK8	S12	P10T	10	Missense	proximal	-2	no	7.207	7.127	EPSD	ICGC;COSMIC	2.638	Down-regulation
CMGC_MAPK_JNK_MAPK8_ST	O43524	FOXO3	P45983	MAPK8	S280	A273G	273	Missense	distal	-7	no	2.651	2.664	EPSD	ICGC;COSMIC	2.638	Up-regulation
CMGC_MAPK_JNK_MAPK8_ST	O43524	FOXO3	P45983	MAPK8	S280	S286T	286	Missense	distal	6	no	2.651	2.648	EPSD	ICGC	2.638	Down-regulation
CMGC_MAPK_JNK_MAPK8_ST	O43524	FOXO3	P45983	MAPK8	S280	S286F	286	Missense	distal	6	no	2.651	2.582	EPSD	ICGC	2.638	Loss
CMGC_MAPK_JNK_MAPK8_ST	O43524	FOXO3	P45983	MAPK8	S284	S286T	286	Missense	proximal	2	no	6.615	6.618	EPSD	ICGC	2.638	Up-regulation
CMGC_MAPK_JNK_MAPK8_ST	O43524	FOXO3	P45983	MAPK8	S284	S286F	286	Missense	proximal	2	no	6.615	6.343	EPSD	ICGC	2.638	Down-regulation
CMGC_MAPK_JNK_MAPK8_ST	O43524	FOXO3	P45983	MAPK8	S311	A317T	317	Missense	distal	6	no	2.674	2.675	EPSD	ICGC;COSMIC	2.638	Up-regulation
CMGC_MAPK_JNK_MAPK8_ST	O43524	FOXO3	P45983	MAPK8	S325	S330N	330	Missense	distal	5	no	8.338	8.407	EPSD	ICGC;COSMIC	2.638	Up-regulation
CMGC_MAPK_JNK_MAPK8_ST	O43524	FOXO3	P45983	MAPK8	S344	D339N	339	Missense	distal	-5	no	7.791	7.998	EPSD	ICGC	2.638	Up-regulation
CMGC_MAPK_JNK_MAPK8_ST	O43524	FOXO3	P45983	MAPK8	S344	D339V	339	Missense	distal	-5	no	7.791	8.091	EPSD	ICGC;COSMIC	2.638	Up-regulation
CMGC_MAPK_JNK_MAPK8_ST	O43524	FOXO3	P45983	MAPK8	S402	S399F	399	Missense	distal	-3	no	7.290	6.916	EPSD	ICGC	2.638	Down-regulation
CMGC_MAPK_JNK_MAPK8_ST	O43524	FOXO3	P45983	MAPK8	S411	P415L	415	Missense	distal	4	no	2.727	2.320	EPSD	ICGC;COSMIC;GDSC	2.638	Loss
CMGC_MAPK_JNK_MAPK8_ST	O43524	FOXO3	P45983	MAPK8	S411	F414L	414	Missense	distal	3	no	2.727	2.735	EPSD	ICGC	2.638	Up-regulation
CMGC_MAPK_JNK_MAPK8_ST	O43524	FOXO3	P45983	MAPK8	S425	G424S	424	Missense	proximal	-1	no	9.449	9.474	EPSD	ICGC;COSMIC	2.638	Up-regulation
CMGC_MAPK_JNK_MAPK8_ST	O43524	FOXO3	P45983	MAPK8	S425	G420S	420	Missense	distal	-5	no	9.449	9.073	EPSD	ICGC;COSMIC	2.638	Down-regulation
CMGC_MAPK_JNK_MAPK8_ST	O43524	FOXO3	P45983	MAPK8	S425	S429Y	429	Missense	distal	4	no	9.449	8.924	EPSD	ICGC;COSMIC	2.638	Down-regulation
CMGC_MAPK_JNK_MAPK8_ST	O43524	FOXO3	P45983	MAPK8	S446	N441K	441	Missense	distal	-5	no	7.804	7.277	EPSD	ICGC	2.638	Down-regulation
CMGC_MAPK_JNK_MAPK8_ST	O43524	FOXO3	P45983	MAPK8	S446	S442F	442	Missense	distal	-4	no	7.804	6.866	EPSD	ICGC;COSMIC	2.638	Down-regulation
CMGC_MAPK_JNK_MAPK8_ST	O43524	FOXO3	P45983	MAPK8	T450	P456Q	456	Missense	distal	6	no	3.347	3.357	EPSD	ICGC;COSMIC	2.638	Up-regulation
CMGC_MAPK_JNK_MAPK8_ST	P10276	RARA	P45983	MAPK8	T181	E183K	183	Missense	proximal	2	no	7.395	7.413	EPSD;PhosphoSitePlus	ICGC;COSMIC	2.638	Up-regulation
CMGC_MAPK_JNK_MAPK8_ST	O43521	BCL2L11	P45983	MAPK8	S59	G62S	62	Missense	distal	3	no	8.407	8.217	EPSD	ICGC;COSMIC	2.638	Down-regulation
CMGC_MAPK_JNK_MAPK8_ST	O43521	BCL2L11	P45983	MAPK8	S59	P56L	56	Missense	distal	-3	no	8.407	8.228	EPSD	ICGC	2.638	Down-regulation
CMGC_MAPK_JNK_MAPK8_ST	O43521	BCL2L11	P45983	MAPK8	S59	G52W	52	Missense	distal	-7	no	8.407	8.411	EPSD	ICGC;COSMIC	2.638	Up-regulation
CMGC_MAPK_JNK_MAPK8_ST	O43521	BCL2L11	P45983	MAPK8	S69	G62S	62	Missense	distal	-7	no	7.830	7.816	EPSD	ICGC;COSMIC	2.638	Down-regulation
CMGC_MAPK_JNK_MAPK8_ST	O43521	BCL2L11	P45983	MAPK8	S77	R84G	84	Missense	distal	7	no	6.762	6.763	EPSD	ICGC;COSMIC	2.638	Up-regulation
CMGC_MAPK_JNK_MAPK8_ST	O43521	BCL2L11	P45983	MAPK8	S94	G95W	95	Missense	proximal	1	no	1.433	2.697	EPSD	ICGC;COSMIC	2.638	Gain
CMGC_MAPK_JNK_MAPK8_ST	O43521	BCL2L11	P45983	MAPK8	T116	K112T	112	Missense	distal	-4	no	8.491	8.164	EPSD	ICGC;COSMIC	2.638	Down-regulation
CMGC_MAPK_JNK_MAPK8_ST	O43521	BCL2L11	P45983	MAPK8	T116	A123T	123	Missense	distal	7	no	8.491	8.493	EPSD	ICGC;COSMIC	2.638	Up-regulation
CMGC_MAPK_JNK_MAPK8_ST	O43521	BCL2L11	P45983	MAPK8	S118	K112T	112	Missense	distal	-6	no	9.230	9.267	EPSD	ICGC;COSMIC	2.638	Up-regulation
CMGC_MAPK_JNK_MAPK8_ST	O43521	BCL2L11	P45983	MAPK8	S118	A123T	123	Missense	distal	5	no	9.230	9.228	EPSD	ICGC;COSMIC	2.638	Down-regulation
CMGC_MAPK_JNK_MAPK8_ST	P38936	CDKN1A	P45983	MAPK8	T57	D52N	52	Missense	distal	-5	no	6.619	6.826	EPSD;PhosphoSitePlus	ICGC;COSMIC	2.638	Up-regulation
CMGC_MAPK_JNK_MAPK8_ST	P38936	CDKN1A	P45983	MAPK8	T57	E56D	56	Missense	proximal	-1	no	6.619	6.601	EPSD;PhosphoSitePlus	ICGC	2.638	Down-regulation
CMGC_MAPK_JNK_MAPK8_ST	P38936	CDKN1A	P45983	MAPK8	T57	F51V	51	Missense	distal	-6	no	6.619	6.643	EPSD;PhosphoSitePlus	ICGC;COSMIC	2.638	Up-regulation
CMGC_MAPK_JNK_MAPK8_ST	P38936	CDKN1A	P45983	MAPK8	S130	P131T	131	Missense	proximal	1	no	9.199	2.213	PhosphoSitePlus;EPSD	ICGC;COSMIC	2.638	Loss
CMGC_MAPK_JNK_MAPK8_ST	P38936	CDKN1A	P45983	MAPK8	S130	P131Q	131	Missense	proximal	1	no	9.199	2.090	PhosphoSitePlus;EPSD	ICGC;COSMIC	2.638	Loss
CMGC_MAPK_JNK_MAPK8_ST	P38936	CDKN1A	P45983	MAPK8	S130	G129W	129	Missense	proximal	-1	no	9.199	9.195	PhosphoSitePlus;EPSD	ICGC;COSMIC	2.638	Down-regulation
CMGC_MAPK_JNK_MAPK8_ST	P54259	ATN1	P45983	MAPK8	S34	P35T	35	Missense	proximal	1	no	6.566	-0.421	EPSD	ICGC;COSMIC	2.638	Loss
CMGC_MAPK_JNK_MAPK8_ST	P54259	ATN1	P45983	MAPK8	T64	R58L	58	Missense	distal	-6	no	7.457	7.482	EPSD	ICGC	2.638	Up-regulation
CMGC_MAPK_JNK_MAPK8_ST	P54259	ATN1	P45983	MAPK8	T64	K69N	69	Missense	distal	5	no	7.457	7.545	EPSD	ICGC	2.638	Up-regulation
CMGC_MAPK_JNK_MAPK8_ST	P54259	ATN1	P45983	MAPK8	S101	S107I	107	Missense	distal	6	no	7.580	7.547	EPSD	ICGC	2.638	Down-regulation
CMGC_MAPK_JNK_MAPK8_ST	P54259	ATN1	P45983	MAPK8	S101	D104Y	104	Missense	distal	3	no	7.580	7.742	EPSD	ICGC	2.638	Up-regulation
CMGC_MAPK_JNK_MAPK8_ST	P54259	ATN1	P45983	MAPK8	S101	R98L	98	Missense	distal	-3	no	7.580	7.544	EPSD	ICGC;COSMIC	2.638	Down-regulation
CMGC_MAPK_JNK_MAPK8_ST	P54259	ATN1	P45983	MAPK8	T131	S132P	132	Missense	proximal	1	no	-0.531	7.198	EPSD	ICGC	2.638	Gain
CMGC_MAPK_JNK_MAPK8_ST	P54259	ATN1	P45983	MAPK8	S132	S134I	134	Missense	proximal	2	no	6.797	6.674	EPSD	ICGC	2.638	Down-regulation
CMGC_MAPK_JNK_MAPK8_ST	P54259	ATN1	P45983	MAPK8	S132	S132P	132	Missense	central	0	yes	6.797	0.000	EPSD	ICGC	2.638	Loss
CMGC_MAPK_JNK_MAPK8_ST	P54259	ATN1	P45983	MAPK8	S134	S134I	134	Missense	central	0	yes	3.767	0.000	EPSD	ICGC	2.638	Loss
CMGC_MAPK_JNK_MAPK8_ST	P54259	ATN1	P45983	MAPK8	S134	S132P	132	Missense	proximal	-2	no	3.767	3.873	EPSD	ICGC	2.638	Up-regulation
CMGC_MAPK_JNK_MAPK8_ST	P54259	ATN1	P45983	MAPK8	S137	S134I	134	Missense	distal	-3	no	7.571	7.412	EPSD	ICGC	2.638	Down-regulation
CMGC_MAPK_JNK_MAPK8_ST	P54259	ATN1	P45983	MAPK8	S137	E142K	142	Missense	distal	5	no	7.571	7.563	EPSD	ICGC;COSMIC	2.638	Down-regulation
CMGC_MAPK_JNK_MAPK8_ST	P54259	ATN1	P45983	MAPK8	S137	S132P	132	Missense	distal	-5	no	7.571	7.683	EPSD	ICGC	2.638	Up-regulation
CMGC_MAPK_JNK_MAPK8_ST	P54259	ATN1	P45983	MAPK8	S168	P169T	169	Missense	proximal	1	no	7.914	0.928	EPSD	ICGC	2.638	Loss
CMGC_MAPK_JNK_MAPK8_ST	P54259	ATN1	P45983	MAPK8	S174	P169T	169	Missense	distal	-5	no	2.737	2.625	EPSD	ICGC	2.638	Loss
CMGC_MAPK_JNK_MAPK8_ST	P54259	ATN1	P45983	MAPK8	T175	P169T	169	Missense	distal	-6	no	7.233	7.169	EPSD	ICGC	2.638	Down-regulation
CMGC_MAPK_JNK_MAPK8_ST	P54259	ATN1	P45983	MAPK8	S355	K348R	348	Missense	distal	-7	no	8.141	8.158	EPSD	ICGC;COSMIC	2.638	Up-regulation
CMGC_MAPK_JNK_MAPK8_ST	P54259	ATN1	P45983	MAPK8	S355	P360L	360	Missense	distal	5	no	8.141	8.139	EPSD	ICGC;COSMIC	2.638	Down-regulation
CMGC_MAPK_JNK_MAPK8_ST	P54259	ATN1	P45983	MAPK8	S355	T351P	351	Missense	distal	-4	no	8.141	7.690	EPSD	ICGC;COSMIC	2.638	Down-regulation
CMGC_MAPK_JNK_MAPK8_ST	P54259	ATN1	P45983	MAPK8	T630	A631T	631	Missense	proximal	1	no	2.902	2.263	EPSD	ICGC;COSMIC	2.638	Loss
CMGC_MAPK_JNK_MAPK8_ST	P54259	ATN1	P45983	MAPK8	S632	A631T	631	Missense	proximal	-1	no	8.266	8.265	EPSD	ICGC;COSMIC	2.638	Down-regulation
CMGC_MAPK_JNK_MAPK8_ST	P54259	ATN1	P45983	MAPK8	S645	A652T	652	Missense	distal	7	no	8.385	8.388	EPSD	ICGC;COSMIC	2.638	Up-regulation
CMGC_MAPK_JNK_MAPK8_ST	P54259	ATN1	P45983	MAPK8	S645	A648V	648	Missense	distal	3	no	8.385	8.613	EPSD	ICGC;COSMIC;GDSC;CCLE	2.638	Up-regulation
CMGC_MAPK_JNK_MAPK8_ST	P54259	ATN1	P45983	MAPK8	T653	A652T	652	Missense	proximal	-1	no	6.419	6.418	EPSD	ICGC;COSMIC	2.638	Down-regulation
CMGC_MAPK_JNK_MAPK8_ST	P54259	ATN1	P45983	MAPK8	T653	G660W	660	Missense	distal	7	no	6.419	6.431	EPSD	ICGC;COSMIC	2.638	Up-regulation
CMGC_MAPK_JNK_MAPK8_ST	P54259	ATN1	P45983	MAPK8	T653	A648V	648	Missense	distal	-5	no	6.419	6.960	EPSD	ICGC;COSMIC;GDSC;CCLE	2.638	Up-regulation
CMGC_MAPK_JNK_MAPK8_ST	P54259	ATN1	P45983	MAPK8	T653	G656E	656	Missense	distal	3	no	6.419	6.242	EPSD	ICGC;COSMIC	2.638	Down-regulation
CMGC_MAPK_JNK_MAPK8_ST	P54259	ATN1	P45983	MAPK8	S661	G660W	660	Missense	proximal	-1	no	6.344	6.339	EPSD	ICGC;COSMIC	2.638	Down-regulation
CMGC_MAPK_JNK_MAPK8_ST	P54259	ATN1	P45983	MAPK8	S661	G656E	656	Missense	distal	-5	no	6.344	5.950	EPSD	ICGC;COSMIC	2.638	Down-regulation
CMGC_MAPK_JNK_MAPK8_ST	P54259	ATN1	P45983	MAPK8	T669	P671L	671	Missense	proximal	2	no	7.862	7.785	EPSD	ICGC	2.638	Down-regulation
CMGC_MAPK_JNK_MAPK8_ST	P54259	ATN1	P45983	MAPK8	S677	S677L	677	Missense	central	0	yes	7.184	0.000	EPSD	ICGC;COSMIC	2.638	Loss
CMGC_MAPK_JNK_MAPK8_ST	P54259	ATN1	P45983	MAPK8	S677	P671L	671	Missense	distal	-6	no	7.184	7.275	EPSD	ICGC	2.638	Up-regulation
CMGC_MAPK_JNK_MAPK8_ST	P54259	ATN1	P45983	MAPK8	S689	V692M	692	Missense	distal	3	no	8.420	8.380	EPSD	ICGC;COSMIC	2.638	Down-regulation
CMGC_MAPK_JNK_MAPK8_ST	P54259	ATN1	P45983	MAPK8	S707	L708P	708	Missense	proximal	1	no	0.815	8.388	EPSD	ICGC;COSMIC	2.638	Gain
CMGC_MAPK_JNK_MAPK8_ST	P54259	ATN1	P45983	MAPK8	T736	Y734F	734	Missense	proximal	-2	no	8.692	8.706	EPSD	ICGC	2.638	Up-regulation
CMGC_MAPK_JNK_MAPK8_ST	P54259	ATN1	P45983	MAPK8	T736	E729K	729	Missense	distal	-7	no	8.692	8.689	EPSD	ICGC	2.638	Down-regulation
CMGC_MAPK_JNK_MAPK8_ST	P54259	ATN1	P45983	MAPK8	T736	P740T	740	Missense	distal	4	no	8.692	8.669	EPSD	ICGC;COSMIC	2.638	Down-regulation
CMGC_MAPK_JNK_MAPK8_ST	P54259	ATN1	P45983	MAPK8	S739	Y734F	734	Missense	distal	-5	no	7.351	7.219	PhosphoSitePlus	ICGC	2.638	Down-regulation
CMGC_MAPK_JNK_MAPK8_ST	P54259	ATN1	P45983	MAPK8	S739	P740T	740	Missense	proximal	1	no	7.351	0.364	PhosphoSitePlus	ICGC;COSMIC	2.638	Loss
CMGC_MAPK_JNK_MAPK8_ST	P54259	ATN1	P45983	MAPK8	S746	P740T	740	Missense	distal	-6	no	8.349	8.285	EPSD	ICGC;COSMIC	2.638	Down-regulation
CMGC_MAPK_JNK_MAPK8_ST	P54259	ATN1	P45983	MAPK8	S780	S780R	780	Missense	central	0	yes	3.794	0.000	EPSD	ICGC;CCLE	2.638	Loss
CMGC_MAPK_JNK_MAPK8_ST	P54259	ATN1	P45983	MAPK8	S896	R900H	900	Missense	distal	4	no	7.337	7.374	EPSD	ICGC;COSMIC	2.638	Up-regulation
CMGC_MAPK_JNK_MAPK8_ST	P54259	ATN1	P45983	MAPK8	S896	R900C	900	Missense	distal	4	no	7.337	7.371	EPSD	ICGC;COSMIC	2.638	Up-regulation
CMGC_MAPK_JNK_MAPK8_ST	P22736	NR4A1	P45983	MAPK8	T10	P15L	15	Missense	distal	5	no	8.351	8.349	EPSD	ICGC;COSMIC	2.638	Down-regulation
CMGC_MAPK_JNK_MAPK8_ST	P22736	NR4A1	P45983	MAPK8	S14	P15L	15	Missense	proximal	1	no	7.779	0.207	EPSD	ICGC;COSMIC	2.638	Loss
CMGC_MAPK_JNK_MAPK8_ST	P22736	NR4A1	P45983	MAPK8	S95	S89F	89	Missense	distal	-6	no	8.503	8.684	PhosphoSitePlus	ICGC	2.638	Up-regulation
CMGC_MAPK_JNK_MAPK8_ST	P22736	NR4A1	P45983	MAPK8	S140	S137W	137	Missense	distal	-3	no	8.612	8.222	EPSD	ICGC;COSMIC	2.638	Down-regulation
CMGC_MAPK_JNK_MAPK8_ST	P22736	NR4A1	P45983	MAPK8	T143	S137W	137	Missense	distal	-6	no	7.362	7.544	EPSD	ICGC;COSMIC	2.638	Up-regulation
CMGC_MAPK_JNK_MAPK8_ST	P22736	NR4A1	P45983	MAPK8	S152	P153H	153	Missense	proximal	1	no	7.205	-0.710	EPSD	ICGC;COSMIC	2.638	Loss
CMGC_MAPK_JNK_MAPK8_ST	P22736	NR4A1	P45983	MAPK8	S360	P357S	357	Missense	distal	-3	no	7.129	7.291	EPSD	ICGC;COSMIC	2.638	Up-regulation
CMGC_MAPK_JNK_MAPK8_ST	P22736	NR4A1	P45983	MAPK8	S360	L364R	364	Missense	distal	4	no	7.129	7.196	EPSD	ICGC;COSMIC	2.638	Up-regulation
CMGC_MAPK_JNK_MAPK8_ST	P22736	NR4A1	P45983	MAPK8	S360	D358N	358	Missense	proximal	-2	no	7.129	7.032	EPSD	ICGC;COSMIC;CCLE	2.638	Down-regulation
CMGC_MAPK_JNK_MAPK8_ST	P22736	NR4A1	P45983	MAPK8	S431	D436Y	436	Missense	distal	5	no	7.530	7.590	EPSD	ICGC;COSMIC	2.638	Up-regulation
CMGC_MAPK_JNK_MAPK8_ST	Q6SZW1	SARM1	P45983	MAPK8	S54	G49R	49	Missense	distal	-5	no	7.357	7.385	EPSD	ICGC	2.638	Up-regulation
CMGC_MAPK_JNK_MAPK8_ST	Q6SZW1	SARM1	P45983	MAPK8	S548	L546P	546	Missense	proximal	-2	no	7.896	8.089	PhosphoSitePlus	ICGC	2.638	Up-regulation
CMGC_MAPK_JNK_MAPK8_ST	P19793	RXRA	P45983	MAPK8	S21	T23M	23	Missense	proximal	2	no	9.786	9.535	EPSD	ICGC;COSMIC	2.638	Down-regulation
CMGC_MAPK_JNK_MAPK8_ST	P19793	RXRA	P45983	MAPK8	S49	G42V	42	Missense	distal	-7	no	7.546	7.551	EPSD	ICGC;COSMIC	2.638	Up-regulation
CMGC_MAPK_JNK_MAPK8_ST	P19793	RXRA	P45983	MAPK8	T82	S88I	88	Missense	distal	6	no	9.219	9.186	EPSD	ICGC	2.638	Down-regulation
CMGC_MAPK_JNK_MAPK8_ST	P19793	RXRA	P45983	MAPK8	S225	E221D	221	Missense	distal	-4	no	4.684	4.261	EPSD	ICGC	2.638	Down-regulation
CMGC_MAPK_JNK_MAPK8_ST	P19793	RXRA	P45983	MAPK8	S225	S224I	224	Missense	proximal	-1	no	4.684	4.672	EPSD	ICGC	2.638	Down-regulation
CMGC_MAPK_JNK_MAPK8_ST	P19793	RXRA	P45983	MAPK8	S260	P258H	258	Missense	proximal	-2	no	7.538	7.354	PhosphoSitePlus	ICGC;COSMIC	2.638	Down-regulation
CMGC_MAPK_JNK_MAPK8_ST	O43379	WDR62	P45983	MAPK8	S6	V4I	4	Missense	proximal	-2	no	2.548	2.685	EPSD	ICGC	2.638	Gain
CMGC_MAPK_JNK_MAPK8_ST	O43379	WDR62	P45983	MAPK8	S32	S33P	33	Missense	proximal	1	no	-0.795	6.933	EPSD	ICGC	2.638	Gain
CMGC_MAPK_JNK_MAPK8_ST	O43379	WDR62	P45983	MAPK8	S33	S33P	33	Missense	central	0	yes	9.448	0.000	EPSD	ICGC	2.638	Loss
CMGC_MAPK_JNK_MAPK8_ST	O43379	WDR62	P45983	MAPK8	S164	M167I	167	Missense	distal	3	no	7.537	7.455	EPSD	ICGC	2.638	Down-regulation
CMGC_MAPK_JNK_MAPK8_ST	O43379	WDR62	P45983	MAPK8	S501	V497G	497	Missense	distal	-4	no	9.046	9.190	EPSD	ICGC;COSMIC	2.638	Up-regulation
CMGC_MAPK_JNK_MAPK8_ST	O43379	WDR62	P45983	MAPK8	T785	E788Q	788	Missense	distal	3	no	8.735	8.779	EPSD	ICGC;COSMIC	2.638	Up-regulation
CMGC_MAPK_JNK_MAPK8_ST	O43379	WDR62	P45983	MAPK8	S791	G795E	795	Missense	distal	4	no	2.745	3.038	EPSD	ICGC;COSMIC	2.638	Up-regulation
CMGC_MAPK_JNK_MAPK8_ST	O43379	WDR62	P45983	MAPK8	S791	E788Q	788	Missense	distal	-3	no	2.745	2.588	EPSD	ICGC;COSMIC	2.638	Loss
CMGC_MAPK_JNK_MAPK8_ST	O43379	WDR62	P45983	MAPK8	S791	S793I	793	Missense	proximal	2	no	2.745	2.622	EPSD	ICGC	2.638	Loss
CMGC_MAPK_JNK_MAPK8_ST	O43379	WDR62	P45983	MAPK8	S793	E799K	799	Missense	distal	6	no	7.263	7.279	EPSD	ICGC;COSMIC	2.638	Up-regulation
CMGC_MAPK_JNK_MAPK8_ST	O43379	WDR62	P45983	MAPK8	S793	G795E	795	Missense	proximal	2	no	7.263	7.528	EPSD	ICGC;COSMIC	2.638	Up-regulation
CMGC_MAPK_JNK_MAPK8_ST	O43379	WDR62	P45983	MAPK8	S793	E788Q	788	Missense	distal	-5	no	7.263	7.370	EPSD	ICGC;COSMIC	2.638	Up-regulation
CMGC_MAPK_JNK_MAPK8_ST	O43379	WDR62	P45983	MAPK8	S793	S793I	793	Missense	central	0	yes	7.263	0.000	EPSD	ICGC	2.638	Loss
CMGC_MAPK_JNK_MAPK8_ST	O43379	WDR62	P45983	MAPK8	T814	D818N	818	Missense	distal	4	no	6.072	5.826	EPSD	ICGC	2.638	Down-regulation
CMGC_MAPK_JNK_MAPK8_ST	O43379	WDR62	P45983	MAPK8	T814	P808Q	808	Missense	distal	-6	no	6.072	6.036	EPSD	ICGC;COSMIC	2.638	Down-regulation
CMGC_MAPK_JNK_MAPK8_ST	O43379	WDR62	P45983	MAPK8	S974	S980Y	980	Missense	distal	6	no	3.174	3.088	EPSD	ICGC;COSMIC	2.638	Down-regulation
CMGC_MAPK_JNK_MAPK8_ST	O43379	WDR62	P45983	MAPK8	S982	S980Y	980	Missense	proximal	-2	no	8.302	8.174	EPSD	ICGC;COSMIC	2.638	Down-regulation
CMGC_MAPK_JNK_MAPK8_ST	O43379	WDR62	P45983	MAPK8	S982	P988Q	988	Missense	distal	6	no	8.302	8.313	EPSD	ICGC;COSMIC	2.638	Up-regulation
CMGC_MAPK_JNK_MAPK8_ST	O43379	WDR62	P45983	MAPK8	S987	S980Y	980	Missense	distal	-7	no	6.571	6.592	EPSD	ICGC;COSMIC	2.638	Up-regulation
CMGC_MAPK_JNK_MAPK8_ST	O43379	WDR62	P45983	MAPK8	S987	P988Q	988	Missense	proximal	1	no	6.571	-0.538	EPSD	ICGC;COSMIC	2.638	Loss
CMGC_MAPK_JNK_MAPK8_ST	O43379	WDR62	P45983	MAPK8	S1044	V1045I	1045	Missense	proximal	1	no	-0.071	2.799	EPSD	ICGC;COSMIC	2.638	Gain
CMGC_MAPK_JNK_MAPK8_ST	O43379	WDR62	P45983	MAPK8	T1053	P1046L	1046	Missense	distal	-7	no	7.656	7.668	PhosphoSitePlus	ICGC;COSMIC	2.638	Up-regulation
CMGC_MAPK_JNK_MAPK8_ST	O43379	WDR62	P45983	MAPK8	S1123	M1129R	1129	Missense	distal	6	no	7.213	7.216	EPSD	ICGC;COSMIC	2.638	Up-regulation
CMGC_MAPK_JNK_MAPK8_ST	O43379	WDR62	P45983	MAPK8	S1144	P1145T	1145	Missense	proximal	1	no	9.398	2.412	EPSD	ICGC;COSMIC	2.638	Loss
CMGC_MAPK_JNK_MAPK8_ST	O43379	WDR62	P45983	MAPK8	S1144	S1144F	1144	Missense	central	0	yes	9.398	0.000	EPSD	ICGC;COSMIC	2.638	Loss
CMGC_MAPK_JNK_MAPK8_ST	O43379	WDR62	P45983	MAPK8	T1191	T1191M	1191	Missense	central	0	yes	6.360	0.000	EPSD	ICGC;CCLE	2.638	Loss
CMGC_MAPK_JNK_MAPK8_ST	O43379	WDR62	P45983	MAPK8	T1197	T1191M	1191	Missense	distal	-6	no	8.988	9.128	EPSD	ICGC;CCLE	2.638	Up-regulation
CMGC_MAPK_JNK_MAPK8_ST	O43379	WDR62	P45983	MAPK8	S1325	A1318V	1318	Missense	distal	-7	no	7.336	7.354	EPSD	ICGC	2.638	Up-regulation
CMGC_MAPK_JNK_MAPK8_ST	O43379	WDR62	P45983	MAPK8	S1348	P1346S	1346	Missense	proximal	-2	no	9.178	9.072	EPSD	ICGC;COSMIC	2.638	Down-regulation
CMGC_MAPK_JNK_MAPK8_ST	O43379	WDR62	P45983	MAPK8	S1348	S1348F	1348	Missense	central	0	yes	9.178	0.000	EPSD	ICGC;COSMIC	2.638	Loss
CMGC_MAPK_JNK_MAPK8_ST	O43379	WDR62	P45983	MAPK8	S1348	P1346A	1346	Missense	proximal	-2	no	9.178	9.128	EPSD	ICGC;COSMIC	2.638	Down-regulation
CMGC_MAPK_JNK_MAPK8_ST	O43379	WDR62	P45983	MAPK8	S1388	L1385F	1385	Missense	distal	-3	no	6.389	6.356	EPSD	ICGC;COSMIC	2.638	Down-regulation
CMGC_MAPK_JNK_MAPK8_ST	O43379	WDR62	P45983	MAPK8	S1388	Q1386H	1386	Missense	proximal	-2	no	6.389	6.315	EPSD	ICGC;COSMIC	2.638	Down-regulation
CMGC_MAPK_JNK_MAPK8_ST	O43379	WDR62	P45983	MAPK8	S1388	A1381T	1381	Missense	distal	-7	no	6.389	6.390	EPSD	ICGC	2.638	Up-regulation
CMGC_MAPK_JNK_MAPK8_ST	O43379	WDR62	P45983	MAPK8	S1405	P1403S	1403	Missense	proximal	-2	no	7.398	7.292	EPSD	ICGC;COSMIC	2.638	Down-regulation
CMGC_MAPK_JNK_MAPK8_ST	O43379	WDR62	P45983	MAPK8	S1405	R1411M	1411	Missense	distal	6	no	7.398	7.395	EPSD	ICGC;COSMIC	2.638	Down-regulation
CMGC_MAPK_JNK_MAPK8_ST	O43379	WDR62	P45983	MAPK8	S1405	P1403L	1403	Missense	proximal	-2	no	7.398	7.205	EPSD	ICGC;COSMIC	2.638	Down-regulation
CMGC_MAPK_JNK_MAPK8_ST	O43379	WDR62	P45983	MAPK8	S1405	A1401V	1401	Missense	distal	-4	no	7.398	6.542	EPSD	ICGC	2.638	Down-regulation
CMGC_MAPK_JNK_MAPK8_ST	O43379	WDR62	P45983	MAPK8	S1405	S1410G	1410	Missense	distal	5	no	7.398	7.466	EPSD	ICGC;COSMIC	2.638	Up-regulation
CMGC_MAPK_JNK_MAPK8_ST	P08047	SP1	P45983	MAPK8	S59	S56A	56	Missense	distal	-3	no	10.071	10.106	EPSD	ICGC;COSMIC	2.638	Up-regulation
CMGC_MAPK_JNK_MAPK8_ST	P08047	SP1	P45983	MAPK8	T117	S114Y	114	Missense	distal	-3	no	7.851	7.367	EPSD	ICGC;COSMIC	2.638	Down-regulation
CMGC_MAPK_JNK_MAPK8_ST	P08047	SP1	P45983	MAPK8	T117	T117I	117	Missense	central	0	yes	7.851	0.000	EPSD	ICGC	2.638	Loss
CMGC_MAPK_JNK_MAPK8_ST	P08047	SP1	P45983	MAPK8	T278	T285M	285	Missense	distal	7	no	8.327	8.387	PhosphoSitePlus;EPSD	ICGC;COSMIC	2.638	Up-regulation
CMGC_MAPK_JNK_MAPK8_ST	P08047	SP1	P45983	MAPK8	T453	T455R	455	Missense	proximal	2	no	8.012	7.767	EPSD	ICGC;COSMIC	2.638	Down-regulation
CMGC_MAPK_JNK_MAPK8_ST	P08047	SP1	P45983	MAPK8	T453	I451V	451	Missense	proximal	-2	no	8.012	7.875	EPSD	ICGC	2.638	Down-regulation
CMGC_MAPK_JNK_MAPK8_ST	P08047	SP1	P45983	MAPK8	S588	Q594E	594	Missense	distal	6	no	7.518	7.534	EPSD	ICGC;COSMIC	2.638	Up-regulation
CMGC_MAPK_JNK_MAPK8_ST	P08047	SP1	P45983	MAPK8	S588	Q592H	592	Missense	distal	4	no	7.518	7.322	EPSD	ICGC	2.638	Down-regulation
CMGC_MAPK_JNK_MAPK8_ST	P08047	SP1	P45983	MAPK8	S588	P589Q	589	Missense	proximal	1	no	7.518	0.409	EPSD	ICGC;COSMIC	2.638	Loss
CMGC_MAPK_JNK_MAPK8_ST	P08047	SP1	P45983	MAPK8	T737	A738G	738	Missense	proximal	1	no	2.815	2.225	EPSD	ICGC;COSMIC	2.638	Loss
CMGC_MAPK_JNK_MAPK8_ST	P08047	SP1	P45983	MAPK8	T739	A738G	738	Missense	proximal	-1	no	9.677	9.651	EPSD;PhosphoSitePlus	ICGC;COSMIC	2.638	Down-regulation
CMGC_MAPK_JNK_MAPK8_ST	P49023	PXN	P45983	MAPK8	S230	S226T	226	Missense	distal	-4	no	8.290	8.076	EPSD	ICGC;COSMIC	2.638	Down-regulation
CMGC_MAPK_JNK_MAPK8_ST	P49023	PXN	P45983	MAPK8	S321	S322L	322	Missense	proximal	1	no	2.663	2.819	EPSD	ICGC;COSMIC	2.638	Up-regulation
CMGC_MAPK_JNK_MAPK8_ST	P49023	PXN	P45983	MAPK8	S321	P328L	328	Missense	distal	7	no	2.663	2.702	EPSD	ICGC	2.638	Up-regulation
CMGC_MAPK_JNK_MAPK8_ST	P49023	PXN	P45983	MAPK8	S322	S322L	322	Missense	central	0	yes	7.138	0.000	EPSD	ICGC;COSMIC	2.638	Loss
CMGC_MAPK_JNK_MAPK8_ST	P49023	PXN	P45983	MAPK8	S322	P328L	328	Missense	distal	6	no	7.138	7.091	EPSD	ICGC	2.638	Down-regulation
CMGC_MAPK_JNK_MAPK8_ST	Q9UQF2	MAPK8IP1	P45983	MAPK8	S6	G7D	7	Missense	proximal	1	no	2.174	2.806	EPSD	ICGC	2.638	Gain
CMGC_MAPK_JNK_MAPK8_ST	Q9UQF2	MAPK8IP1	P45983	MAPK8	S15	S15N	15	Missense	central	0	yes	8.376	0.000	EPSD	ICGC;COSMIC	2.638	Loss
CMGC_MAPK_JNK_MAPK8_ST	Q9UQF2	MAPK8IP1	P45983	MAPK8	S15	G8V	8	Missense	distal	-7	no	8.376	8.381	EPSD	ICGC	2.638	Up-regulation
CMGC_MAPK_JNK_MAPK8_ST	Q9UQF2	MAPK8IP1	P45983	MAPK8	S15	P21R	21	Missense	distal	6	no	8.376	8.341	EPSD	ICGC;COSMIC	2.638	Down-regulation
CMGC_MAPK_JNK_MAPK8_ST	Q9UQF2	MAPK8IP1	P45983	MAPK8	S15	P17L	17	Missense	proximal	2	no	8.376	8.300	EPSD	ICGC;COSMIC	2.638	Down-regulation
CMGC_MAPK_JNK_MAPK8_ST	Q9UQF2	MAPK8IP1	P45983	MAPK8	S15	A18T	18	Missense	distal	3	no	8.376	8.386	EPSD	ICGC;COSMIC	2.638	Up-regulation
CMGC_MAPK_JNK_MAPK8_ST	Q9UQF2	MAPK8IP1	P45983	MAPK8	S20	S15N	15	Missense	distal	-5	no	7.803	8.235	EPSD	ICGC;COSMIC	2.638	Up-regulation
CMGC_MAPK_JNK_MAPK8_ST	Q9UQF2	MAPK8IP1	P45983	MAPK8	S20	P21R	21	Missense	proximal	1	no	7.803	0.667	EPSD	ICGC;COSMIC	2.638	Loss
CMGC_MAPK_JNK_MAPK8_ST	Q9UQF2	MAPK8IP1	P45983	MAPK8	S20	P17L	17	Missense	distal	-3	no	7.803	7.624	EPSD	ICGC;COSMIC	2.638	Down-regulation
CMGC_MAPK_JNK_MAPK8_ST	Q9UQF2	MAPK8IP1	P45983	MAPK8	S20	A18T	18	Missense	proximal	-2	no	7.803	7.773	EPSD	ICGC;COSMIC	2.638	Down-regulation
CMGC_MAPK_JNK_MAPK8_ST	Q07817	BCL2L1	P45983	MAPK8	T47	E44D	44	Missense	distal	-3	no	7.989	7.750	PhosphoSitePlus;EPSD	ICGC;COSMIC	2.638	Down-regulation
CMGC_MAPK_JNK_MAPK8_ST	Q07817	BCL2L1	P45983	MAPK8	T47	T47I	47	Missense	central	0	yes	7.989	0.000	PhosphoSitePlus;EPSD	ICGC;COSMIC	2.638	Loss
CMGC_MAPK_JNK_MAPK8_ST	Q07817	BCL2L1	P45983	MAPK8	S62	P63T	63	Missense	proximal	1	no	6.612	-0.374	EPSD;PhosphoSitePlus	ICGC	2.638	Loss
CMGC_MAPK_JNK_MAPK8_ST	Q07817	BCL2L1	P45983	MAPK8	T115	S122R	122	Missense	distal	7	no	7.756	7.819	EPSD;PhosphoSitePlus	ICGC	2.638	Up-regulation
CMGC_MAPK_JNK_MAPK8_ST	Q07817	BCL2L1	P45983	MAPK8	T115	T118K	118	Missense	distal	3	no	7.756	7.687	EPSD;PhosphoSitePlus	ICGC	2.638	Down-regulation
CMGC_MAPK_JNK_MAPK8_ST	Q07817	BCL2L1	P45983	MAPK8	T115	T109K	109	Missense	distal	-6	no	7.756	7.719	EPSD;PhosphoSitePlus	ICGC	2.638	Down-regulation
CMGC_MAPK_JNK_MAPK8_ST	O43561	LAT	P45983	MAPK8	S41	P46S	46	Missense	distal	5	no	2.753	2.669	EPSD	ICGC;COSMIC;GDSC	2.638	Down-regulation
CMGC_MAPK_JNK_MAPK8_ST	O43561	LAT	P45983	MAPK8	S84	P80S	80	Missense	distal	-4	no	6.397	7.062	EPSD	ICGC;COSMIC	2.638	Up-regulation
CMGC_MAPK_JNK_MAPK8_ST	O43561	LAT	P45983	MAPK8	S84	P82L	82	Missense	proximal	-2	no	6.397	6.204	EPSD	ICGC;COSMIC	2.638	Down-regulation
CMGC_MAPK_JNK_MAPK8_ST	O43561	LAT	P45983	MAPK8	S84	P80T	80	Missense	distal	-4	no	6.397	6.847	EPSD	ICGC;COSMIC	2.638	Up-regulation
CMGC_MAPK_JNK_MAPK8_ST	O43561	LAT	P45983	MAPK8	T94	S96F	96	Missense	proximal	2	no	6.976	6.705	EPSD	ICGC;COSMIC	2.638	Down-regulation
CMGC_MAPK_JNK_MAPK8_ST	O43561	LAT	P45983	MAPK8	T94	R98Q	98	Missense	distal	4	no	6.976	7.210	EPSD	ICGC	2.638	Up-regulation
CMGC_MAPK_JNK_MAPK8_ST	P42226	STAT6	P45983	MAPK8	S498	V497L	497	Missense	proximal	-1	no	3.007	3.012	EPSD	ICGC;COSMIC	2.638	Up-regulation
CMGC_MAPK_JNK_MAPK8_ST	P42226	STAT6	P45983	MAPK8	S707	P702Q	702	Missense	distal	-5	no	6.698	6.675	PhosphoSitePlus	ICGC	2.638	Down-regulation
CMGC_MAPK_JNK_MAPK8_ST	P42226	STAT6	P45983	MAPK8	S707	G705S	705	Missense	proximal	-2	no	6.698	6.763	PhosphoSitePlus	ICGC	2.638	Up-regulation
CMGC_MAPK_JNK_MAPK8_ST	P42226	STAT6	P45983	MAPK8	S707	N713S	713	Missense	distal	6	no	6.698	6.763	PhosphoSitePlus	ICGC;COSMIC	2.638	Up-regulation
CMGC_MAPK_JNK_MAPK8_ST	Q13950	RUNX2	P45983	MAPK8	S275	P276S	276	Missense	proximal	1	no	8.216	0.487	EPSD	ICGC	2.638	Loss
CMGC_MAPK_JNK_MAPK8_ST	Q14934	NFATC4	P45983	MAPK8	S73	R77H	77	Missense	distal	4	no	7.174	7.211	EPSD	ICGC;COSMIC	2.638	Up-regulation
CMGC_MAPK_JNK_MAPK8_ST	Q14934	NFATC4	P45983	MAPK8	S73	P74L	74	Missense	proximal	1	no	7.174	-0.398	EPSD	ICGC;COSMIC	2.638	Loss
CMGC_MAPK_JNK_MAPK8_ST	Q14934	NFATC4	P45983	MAPK8	S311	P314L	314	Missense	distal	3	no	6.901	7.002	EPSD	ICGC;COSMIC	2.638	Up-regulation
CMGC_MAPK_JNK_MAPK8_ST	Q14934	NFATC4	P45983	MAPK8	S395	P396S	396	Missense	proximal	1	no	7.287	-0.442	EPSD	ICGC;COSMIC	2.638	Loss
CMGC_MAPK_JNK_MAPK8_ST	Q14934	NFATC4	P45983	MAPK8	S592	V598F	598	Missense	distal	6	no	5.352	5.362	EPSD	ICGC;COSMIC	2.638	Up-regulation
CMGC_MAPK_JNK_MAPK8_ST	Q14934	NFATC4	P45983	MAPK8	S592	V588A	588	Missense	distal	-4	no	5.352	6.208	EPSD	ICGC;COSMIC	2.638	Up-regulation
CMGC_MAPK_JNK_MAPK8_ST	Q14934	NFATC4	P45983	MAPK8	S716	F715C	715	Missense	proximal	-1	no	8.381	8.392	EPSD	ICGC;COSMIC	2.638	Up-regulation
CMGC_MAPK_JNK_MAPK8_ST	Q14934	NFATC4	P45983	MAPK8	S819	P820S	820	Missense	proximal	1	no	6.902	-0.827	EPSD	ICGC;COSMIC	2.638	Loss
CMGC_MAPK_JNK_MAPK8_ST	P17535	JUND	P45983	MAPK8	T71	R74S	74	Missense	distal	3	no	7.734	7.552	EPSD	ICGC	2.638	Down-regulation
CMGC_MAPK_JNK_MAPK8_ST	P17535	JUND	P45983	MAPK8	S100	R105C	105	Missense	distal	5	no	7.661	7.643	PhosphoSitePlus	ICGC;COSMIC	2.638	Down-regulation
CMGC_MAPK_JNK_MAPK8_ST	P17535	JUND	P45983	MAPK8	T117	T115S	115	Missense	proximal	-2	no	6.524	6.499	EPSD	ICGC;COSMIC	2.638	Down-regulation
CMGC_MAPK_JNK_MAPK8_ST	P17535	JUND	P45983	MAPK8	S255	S251N	251	Missense	distal	-4	no	6.957	6.083	EPSD	ICGC;COSMIC	2.638	Down-regulation
CMGC_MAPK_JNK_MAPK8_ST	P17535	JUND	P45983	MAPK8	S255	P250S	250	Missense	distal	-5	no	6.957	6.845	EPSD	ICGC	2.638	Down-regulation
CMGC_MAPK_JNK_MAPK8_ST	P17535	JUND	P45983	MAPK8	S315	T313K	313	Missense	proximal	-2	no	2.657	2.662	EPSD	ICGC	2.638	Up-regulation
CMGC_MAPK_JNK_MAPK8_ST	P17535	JUND	P45983	MAPK8	S315	L310M	310	Missense	distal	-5	no	2.657	2.626	EPSD	ICGC	2.638	Loss
CMGC_MAPK_JNK_MAPK8_ST	P17535	JUND	P45983	MAPK8	S315	A314S	314	Missense	proximal	-1	no	2.657	2.656	EPSD	ICGC	2.638	Down-regulation
CMGC_MAPK_JNK_MAPK8_ST	P17535	JUND	P45983	MAPK8	S315	L317P	317	Missense	proximal	2	no	2.657	2.734	EPSD	ICGC;COSMIC	2.638	Up-regulation
CMGC_MAPK_JNK_MAPK8_ST	P85298	ARHGAP8	P45983	MAPK8	T206	P213Q	213	Missense	distal	7	no	8.983	8.961	EPSD	ICGC;COSMIC	2.638	Down-regulation
CMGC_MAPK_JNK_MAPK8_ST	P85298	ARHGAP8	P45983	MAPK8	T212	P218Q	218	Missense	distal	6	no	6.469	6.479	EPSD	ICGC;COSMIC	2.638	Up-regulation
CMGC_MAPK_JNK_MAPK8_ST	P85298	ARHGAP8	P45983	MAPK8	T212	P213Q	213	Missense	proximal	1	no	6.469	-0.641	EPSD	ICGC;COSMIC	2.638	Loss
CMGC_MAPK_JNK_MAPK8_ST	P10415	BCL2	P45983	MAPK8	T56	A60V	60	Missense	distal	4	no	9.128	8.609	EPSD	ICGC;COSMIC;GDSC;CCLE	2.638	Down-regulation
CMGC_MAPK_JNK_MAPK8_ST	P10415	BCL2	P45983	MAPK8	T56	H58Q	58	Missense	proximal	2	no	9.128	9.244	EPSD	ICGC;COSMIC	2.638	Up-regulation
CMGC_MAPK_JNK_MAPK8_ST	P10415	BCL2	P45983	MAPK8	T56	H58P	58	Missense	proximal	2	no	9.128	9.126	EPSD	ICGC	2.638	Down-regulation
CMGC_MAPK_JNK_MAPK8_ST	P10415	BCL2	P45983	MAPK8	T56	P59A	59	Missense	distal	3	no	9.128	9.020	EPSD	ICGC;COSMIC;GDSC;CCLE	2.638	Down-regulation
CMGC_MAPK_JNK_MAPK8_ST	P10415	BCL2	P45983	MAPK8	T56	S62F	62	Missense	distal	6	no	9.128	9.059	EPSD	ICGC;COSMIC	2.638	Down-regulation
CMGC_MAPK_JNK_MAPK8_ST	P10415	BCL2	P45983	MAPK8	T56	P59S	59	Missense	distal	3	no	9.128	9.002	EPSD	ICGC;COSMIC	2.638	Down-regulation
CMGC_MAPK_JNK_MAPK8_ST	P10415	BCL2	P45983	MAPK8	T56	P53S	53	Missense	distal	-3	no	9.128	9.290	EPSD	ICGC;COSMIC	2.638	Up-regulation
CMGC_MAPK_JNK_MAPK8_ST	P10415	BCL2	P45983	MAPK8	T56	P59L	59	Missense	distal	3	no	9.128	9.229	EPSD	ICGC;COSMIC;GDSC;CCLE	2.638	Up-regulation
CMGC_MAPK_JNK_MAPK8_ST	P10415	BCL2	P45983	MAPK8	T56	Q52R	52	Missense	distal	-4	no	9.128	8.607	EPSD	ICGC;COSMIC	2.638	Down-regulation
CMGC_MAPK_JNK_MAPK8_ST	P10415	BCL2	P45983	MAPK8	T56	F49L	49	Missense	distal	-7	no	9.128	9.129	EPSD	ICGC;COSMIC	2.638	Up-regulation
CMGC_MAPK_JNK_MAPK8_ST	P10415	BCL2	P45983	MAPK8	T56	A60T	60	Missense	distal	4	no	9.128	9.079	EPSD	ICGC;COSMIC	2.638	Down-regulation
CMGC_MAPK_JNK_MAPK8_ST	P10415	BCL2	P45983	MAPK8	T56	T56M	56	Missense	central	0	yes	9.128	0.000	EPSD	ICGC	2.638	Loss
CMGC_MAPK_JNK_MAPK8_ST	P10415	BCL2	P45983	MAPK8	T74	A81V	81	Missense	distal	7	no	9.142	9.221	EPSD	ICGC;COSMIC	2.638	Up-regulation
CMGC_MAPK_JNK_MAPK8_ST	P10415	BCL2	P45983	MAPK8	S87	P88Q	88	Missense	proximal	1	no	7.709	0.600	EPSD;PhosphoSitePlus	ICGC;COSMIC	2.638	Loss
CMGC_MAPK_JNK_MAPK8_ST	P10415	BCL2	P45983	MAPK8	S87	L86V	86	Missense	proximal	-1	no	7.709	7.704	EPSD;PhosphoSitePlus	ICGC;COSMIC;GDSC;CCLE	2.638	Down-regulation
CMGC_MAPK_JNK_MAPK8_ST	P10415	BCL2	P45983	MAPK8	S87	S87R	87	Missense	central	0	yes	7.709	0.000	EPSD;PhosphoSitePlus	ICGC;COSMIC	2.638	Loss
CMGC_MAPK_JNK_MAPK8_ST	P10415	BCL2	P45983	MAPK8	S87	A81V	81	Missense	distal	-6	no	7.709	7.910	EPSD;PhosphoSitePlus	ICGC;COSMIC	2.638	Up-regulation
CMGC_MAPK_JNK_MAPK8_ST	Q9Y6Q9	NCOA3	P45983	MAPK8	S13	N7S	7	Missense	distal	-6	no	3.637	3.461	EPSD	ICGC;COSMIC	2.638	Down-regulation
CMGC_MAPK_JNK_MAPK8_ST	Q9Y6Q9	NCOA3	P45983	MAPK8	S13	R16Q	16	Missense	distal	3	no	3.637	3.511	EPSD	ICGC;COSMIC	2.638	Down-regulation
CMGC_MAPK_JNK_MAPK8_ST	Q9Y6Q9	NCOA3	P45983	MAPK8	T203	D210N	210	Missense	distal	7	no	7.504	7.533	EPSD	ICGC;COSMIC	2.638	Up-regulation
CMGC_MAPK_JNK_MAPK8_ST	Q9Y6Q9	NCOA3	P45983	MAPK8	S214	D210N	210	Missense	distal	-4	no	7.609	7.301	EPSD	ICGC;COSMIC	2.638	Down-regulation
CMGC_MAPK_JNK_MAPK8_ST	Q9Y6Q9	NCOA3	P45983	MAPK8	S423	S423N	423	Missense	central	0	yes	2.882	0.000	EPSD	ICGC;COSMIC	2.638	Loss
CMGC_MAPK_JNK_MAPK8_ST	Q9Y6Q9	NCOA3	P45983	MAPK8	S423	G418V	418	Missense	distal	-5	no	2.882	3.031	EPSD	ICGC	2.638	Up-regulation
CMGC_MAPK_JNK_MAPK8_ST	Q9Y6Q9	NCOA3	P45983	MAPK8	S423	G426V	426	Missense	distal	3	no	2.882	2.938	EPSD	ICGC	2.638	Up-regulation
CMGC_MAPK_JNK_MAPK8_ST	Q9Y6Q9	NCOA3	P45983	MAPK8	S465	H468L	468	Missense	distal	3	no	7.105	7.169	EPSD	ICGC;COSMIC	2.638	Up-regulation
CMGC_MAPK_JNK_MAPK8_ST	Q9Y6Q9	NCOA3	P45983	MAPK8	S470	H468L	468	Missense	proximal	-2	no	8.539	8.530	EPSD	ICGC;COSMIC	2.638	Down-regulation
CMGC_MAPK_JNK_MAPK8_ST	Q9Y6Q9	NCOA3	P45983	MAPK8	S505	S498F	498	Missense	distal	-7	no	8.149	8.165	EPSD;PhosphoSitePlus	ICGC;COSMIC	2.638	Up-regulation
CMGC_MAPK_JNK_MAPK8_ST	Q9Y6Q9	NCOA3	P45983	MAPK8	S543	L548W	548	Missense	distal	5	no	9.869	9.882	EPSD;PhosphoSitePlus	ICGC;COSMIC	2.638	Up-regulation
CMGC_MAPK_JNK_MAPK8_ST	Q9Y6Q9	NCOA3	P45983	MAPK8	S551	L548W	548	Missense	distal	-3	no	6.839	6.791	EPSD	ICGC;COSMIC	2.638	Down-regulation
CMGC_MAPK_JNK_MAPK8_ST	Q9Y6Q9	NCOA3	P45983	MAPK8	S569	D576Y	576	Missense	distal	7	no	8.341	8.395	EPSD	ICGC;COSMIC	2.638	Up-regulation
CMGC_MAPK_JNK_MAPK8_ST	Q9Y6Q9	NCOA3	P45983	MAPK8	S640	S635F	635	Missense	distal	-5	no	8.093	8.562	EPSD	ICGC	2.638	Up-regulation
CMGC_MAPK_JNK_MAPK8_ST	Q9Y6Q9	NCOA3	P45983	MAPK8	S694	A696T	696	Missense	proximal	2	no	7.525	7.504	EPSD	ICGC	2.638	Down-regulation
CMGC_MAPK_JNK_MAPK8_ST	Q9Y6Q9	NCOA3	P45983	MAPK8	S712	T714A	714	Missense	proximal	2	no	2.624	2.645	EPSD	ICGC	2.638	Gain
CMGC_MAPK_JNK_MAPK8_ST	Q9Y6Q9	NCOA3	P45983	MAPK8	T914	S917T	917	Missense	distal	3	no	8.452	8.480	EPSD	ICGC;COSMIC	2.638	Up-regulation
CMGC_MAPK_JNK_MAPK8_ST	Q9Y6Q9	NCOA3	P45983	MAPK8	T914	V911M	911	Missense	distal	-3	no	8.452	8.520	EPSD	ICGC;COSMIC	2.638	Up-regulation
CMGC_MAPK_JNK_MAPK8_ST	Q9Y6Q9	NCOA3	P45983	MAPK8	S1330	A1324S	1324	Missense	distal	-6	no	8.361	8.358	EPSD	ICGC	2.638	Down-regulation
CMGC_MAPK_JNK_MAPK8_ST	Q15672	TWIST1	P45983	MAPK8	S42	R37H	37	Missense	distal	-5	no	2.687	2.591	EPSD	ICGC	2.638	Loss
CMGC_MAPK_JNK_MAPK8_ST	Q15672	TWIST1	P45983	MAPK8	S68	Q71R	71	Missense	distal	3	no	8.688	8.814	PhosphoSitePlus	ICGC	2.638	Up-regulation
CMGC_MAPK_JNK_MAPK8_ST	Q15672	TWIST1	P45983	MAPK8	S68	P66L	66	Missense	proximal	-2	no	8.688	8.495	PhosphoSitePlus	ICGC	2.638	Down-regulation
CMGC_MAPK_JNK_MAPK8_ST	Q15672	TWIST1	P45983	MAPK8	S68	G67A	67	Missense	proximal	-1	no	8.688	8.714	PhosphoSitePlus	ICGC	2.638	Up-regulation
CMGC_MAPK_JNK_MAPK8_ST	Q15672	TWIST1	P45983	MAPK8	S95	G92S	92	Missense	distal	-3	no	3.031	3.312	EPSD	ICGC;COSMIC;CCLE	2.638	Up-regulation
CMGC_MAPK_JNK_MAPK8_ST	Q15672	TWIST1	P45983	MAPK8	S95	S93G	93	Missense	proximal	-2	no	3.031	2.966	EPSD	ICGC	2.638	Down-regulation
CMGC_MAPK_JNK_MAPK8_ST	Q15672	TWIST1	P45983	MAPK8	S95	S95G	95	Missense	central	0	yes	3.031	0.000	EPSD	ICGC;COSMIC	2.638	Loss
CMGC_MAPK_JNK_MAPK8_ST	Q15672	TWIST1	P45983	MAPK8	S95	G90C	90	Missense	distal	-5	no	3.031	2.960	EPSD	ICGC;COSMIC	2.638	Down-regulation
CMGC_MAPK_JNK_MAPK8_ST	Q15672	TWIST1	P45983	MAPK8	S99	G92S	92	Missense	distal	-7	no	8.122	8.108	EPSD	ICGC;COSMIC;CCLE	2.638	Down-regulation
CMGC_MAPK_JNK_MAPK8_ST	Q15672	TWIST1	P45983	MAPK8	S99	S93G	93	Missense	distal	-6	no	8.122	8.273	EPSD	ICGC	2.638	Up-regulation
CMGC_MAPK_JNK_MAPK8_ST	Q15672	TWIST1	P45983	MAPK8	S99	S95G	95	Missense	distal	-4	no	8.122	7.233	EPSD	ICGC;COSMIC	2.638	Down-regulation
CMGC_MAPK_JNK_MAPK8_ST	Q9NR28	DIABLO	P45983	MAPK8	S6	T13N	13	Missense	distal	7	no	3.765	3.826	EPSD;PhosphoSitePlus	ICGC	2.638	Up-regulation
CMGC_MAPK_JNK_MAPK8_ST	Q9NR28	DIABLO	P45983	MAPK8	S6	S6G	6	Missense	central	0	yes	3.765	0.000	EPSD;PhosphoSitePlus	ICGC	2.638	Loss
CMGC_MAPK_JNK_MAPK8_ST	Q9NR28	DIABLO	P45983	MAPK8	S6	A2V	2	Missense	distal	-4	no	3.765	2.909	EPSD;PhosphoSitePlus	ICGC;COSMIC	2.638	Down-regulation
CMGC_MAPK_JNK_MAPK8_ST	Q9NR28	DIABLO	P45983	MAPK8	S9	T13N	13	Missense	distal	4	no	2.968	2.568	PhosphoSitePlus;EPSD	ICGC	2.638	Loss
CMGC_MAPK_JNK_MAPK8_ST	Q9NR28	DIABLO	P45983	MAPK8	S9	S6G	6	Missense	distal	-3	no	2.968	2.687	PhosphoSitePlus;EPSD	ICGC	2.638	Down-regulation
CMGC_MAPK_JNK_MAPK8_ST	Q9NR28	DIABLO	P45983	MAPK8	S9	A2V	2	Missense	distal	-7	no	2.968	2.986	PhosphoSitePlus;EPSD	ICGC;COSMIC	2.638	Up-regulation
CMGC_MAPK_JNK_MAPK8_ST	Q9UGP4	LIMD1	P45983	MAPK8	S211	P212Q	212	Missense	proximal	1	no	8.655	1.546	EPSD	ICGC;COSMIC	2.638	Loss
CMGC_MAPK_JNK_MAPK8_ST	Q9UGP4	LIMD1	P45983	MAPK8	T260	L262P	262	Missense	proximal	2	no	2.882	2.959	EPSD	ICGC;COSMIC	2.638	Up-regulation
CMGC_MAPK_JNK_MAPK8_ST	Q9UGP4	LIMD1	P45983	MAPK8	T260	W263L	263	Missense	distal	3	no	2.882	2.877	EPSD	ICGC	2.638	Down-regulation
CMGC_MAPK_JNK_MAPK8_ST	Q9UGP4	LIMD1	P45983	MAPK8	S268	L262P	262	Missense	distal	-6	no	3.243	3.152	EPSD	ICGC;COSMIC	2.638	Down-regulation
CMGC_MAPK_JNK_MAPK8_ST	Q9UGP4	LIMD1	P45983	MAPK8	S268	W263L	263	Missense	distal	-5	no	3.243	3.265	EPSD	ICGC	2.638	Up-regulation
CMGC_MAPK_JNK_MAPK8_ST	Q9UGP4	LIMD1	P45983	MAPK8	T294	S296P	296	Missense	proximal	2	no	7.586	7.401	EPSD	ICGC;COSMIC	2.638	Down-regulation
CMGC_MAPK_JNK_MAPK8_ST	Q9UGP4	LIMD1	P45983	MAPK8	T294	A299T	299	Missense	distal	5	no	7.586	7.584	EPSD	ICGC;COSMIC;CCLE	2.638	Down-regulation
CMGC_MAPK_JNK_MAPK8_ST	Q9UGP4	LIMD1	P45983	MAPK8	S353	G359R	359	Missense	distal	6	no	8.411	8.408	EPSD	ICGC;COSMIC	2.638	Down-regulation
CMGC_MAPK_JNK_MAPK8_ST	Q9UGP4	LIMD1	P45983	MAPK8	S353	G359C	359	Missense	distal	6	no	8.411	8.420	EPSD	ICGC;COSMIC	2.638	Up-regulation
CMGC_MAPK_JNK_MAPK8_ST	Q9UGP4	LIMD1	P45983	MAPK8	S421	R428G	428	Missense	distal	7	no	6.910	6.912	EPSD;PhosphoSitePlus	ICGC	2.638	Up-regulation
CMGC_MAPK_JNK_MAPK8_ST	Q9UGP4	LIMD1	P45983	MAPK8	S421	S416Y	416	Missense	distal	-5	no	6.910	7.510	EPSD;PhosphoSitePlus	ICGC	2.638	Up-regulation
CMGC_MAPK_JNK_MAPK8_ST	Q9UGP4	LIMD1	P45983	MAPK8	S424	R428G	428	Missense	distal	4	no	8.533	8.554	EPSD;PhosphoSitePlus	ICGC	2.638	Up-regulation
CMGC_MAPK_JNK_MAPK8_ST	P35222	CTNNB1	P45983	MAPK8	S246	L252H	252	Missense	distal	6	no	7.678	7.701	EPSD	ICGC;COSMIC	2.638	Up-regulation
CMGC_MAPK_JNK_MAPK8_ST	Q99607	ELF4	P45983	MAPK8	S188	T191N	191	Missense	distal	3	no	6.118	6.294	EPSD	ICGC	2.638	Up-regulation
CMGC_MAPK_JNK_MAPK8_ST	Q99607	ELF4	P45983	MAPK8	S194	T191N	191	Missense	distal	-3	no	2.695	2.360	EPSD	ICGC	2.638	Loss
CMGC_MAPK_JNK_MAPK8_ST	Q99607	ELF4	P45983	MAPK8	S194	R198S	198	Missense	distal	4	no	2.695	3.060	EPSD	ICGC;COSMIC	2.638	Up-regulation
CMGC_MAPK_JNK_MAPK8_ST	Q99607	ELF4	P45983	MAPK8	T531	E538D	538	Missense	distal	7	no	3.257	3.297	EPSD	ICGC;COSMIC	2.638	Up-regulation
CMGC_MAPK_JNK_MAPK8_ST	Q99607	ELF4	P45983	MAPK8	S641	S641P	641	Missense	central	0	yes	8.197	0.000	PhosphoSitePlus	ICGC	2.638	Loss
CMGC_MAPK_JNK_MAPK8_ST	Q99607	ELF4	P45983	MAPK8	S641	S636R	636	Missense	distal	-5	no	8.197	8.601	PhosphoSitePlus	ICGC;COSMIC	2.638	Up-regulation
CMGC_MAPK_JNK_MAPK8_ST	Q99607	ELF4	P45983	MAPK8	T643	S641P	641	Missense	proximal	-2	no	6.925	7.030	EPSD	ICGC	2.638	Up-regulation
CMGC_MAPK_JNK_MAPK8_ST	Q99607	ELF4	P45983	MAPK8	T643	S636R	636	Missense	distal	-7	no	6.925	6.939	EPSD	ICGC;COSMIC	2.638	Up-regulation
CMGC_MAPK_JNK_MAPK8_ST	Q99607	ELF4	P45983	MAPK8	S648	S641P	641	Missense	distal	-7	no	7.748	7.754	EPSD	ICGC	2.638	Up-regulation
CMGC_MAPK_JNK_MAPK8_ST	P05412	JUN	P45983	MAPK8	S63	K70T	70	Missense	distal	7	no	7.247	7.269	EPSD;PhosphoSitePlus	ICGC;COSMIC	2.638	Up-regulation
CMGC_MAPK_JNK_MAPK8_ST	P05412	JUN	P45983	MAPK8	S73	A72E	72	Missense	proximal	-1	no	8.495	8.497	PhosphoSitePlus;EPSD	ICGC;COSMIC	2.638	Up-regulation
CMGC_MAPK_JNK_MAPK8_ST	P05412	JUN	P45983	MAPK8	S73	K70T	70	Missense	distal	-3	no	8.495	8.398	PhosphoSitePlus;EPSD	ICGC;COSMIC	2.638	Down-regulation
CMGC_MAPK_JNK_MAPK8_ST	P05412	JUN	P45983	MAPK8	T91	T93N	93	Missense	proximal	2	no	8.328	8.063	EPSD;PhosphoSitePlus	ICGC	2.638	Down-regulation
CMGC_MAPK_JNK_MAPK8_ST	P05412	JUN	P45983	MAPK8	T91	L98R	98	Missense	distal	7	no	8.328	8.313	EPSD;PhosphoSitePlus	ICGC	2.638	Down-regulation
CMGC_MAPK_JNK_MAPK8_ST	P05412	JUN	P45983	MAPK8	T93	T93N	93	Missense	central	0	yes	8.490	0.000	EPSD;PhosphoSitePlus	ICGC	2.638	Loss
CMGC_MAPK_JNK_MAPK8_ST	P05412	JUN	P45983	MAPK8	T93	L98R	98	Missense	distal	5	no	8.490	8.480	EPSD;PhosphoSitePlus	ICGC	2.638	Down-regulation
CMGC_MAPK_JNK_MAPK8_ST	P05412	JUN	P45983	MAPK8	T239	T239K	239	Missense	central	0	yes	5.188	0.000	EPSD	ICGC	2.638	Loss
CMGC_MAPK_JNK_MAPK8_ST	P05412	JUN	P45983	MAPK8	S243	T239K	239	Missense	distal	-4	no	7.365	7.692	EPSD	ICGC	2.638	Up-regulation
CMGC_MAPK_JNK_MAPK8_ST	Q14451	GRB7	P45983	MAPK8	S6	S12G	12	Missense	distal	6	no	8.652	8.596	EPSD	ICGC;COSMIC	2.638	Down-regulation
CMGC_MAPK_JNK_MAPK8_ST	Q14451	GRB7	P45983	MAPK8	S13	S12G	12	Missense	proximal	-1	no	6.680	6.655	EPSD	ICGC;COSMIC	2.638	Down-regulation
CMGC_MAPK_JNK_MAPK8_ST	Q14451	GRB7	P45983	MAPK8	T33	K40N	40	Missense	distal	7	no	6.076	6.160	EPSD	ICGC;COSMIC	2.638	Up-regulation
CMGC_MAPK_JNK_MAPK8_ST	Q14451	GRB7	P45983	MAPK8	S194	P195L	195	Missense	proximal	1	no	8.573	1.000	PhosphoSitePlus	ICGC	2.638	Loss
CMGC_MAPK_JNK_MAPK8_ST	P30305	CDC25B	P45983	MAPK8	S15	S12W	12	Missense	distal	-3	no	7.907	7.517	EPSD	ICGC;COSMIC	2.638	Down-regulation
CMGC_MAPK_JNK_MAPK8_ST	P30305	CDC25B	P45983	MAPK8	S15	P8S	8	Missense	distal	-7	no	7.907	7.901	EPSD	ICGC;COSMIC	2.638	Down-regulation
CMGC_MAPK_JNK_MAPK8_ST	P30305	CDC25B	P45983	MAPK8	S15	L14V	14	Missense	proximal	-1	no	7.907	7.902	EPSD	ICGC;COSMIC	2.638	Down-regulation
CMGC_MAPK_JNK_MAPK8_ST	P30305	CDC25B	P45983	MAPK8	S42	G38D	38	Missense	distal	-4	no	8.088	8.410	EPSD	ICGC;COSMIC	2.638	Up-regulation
CMGC_MAPK_JNK_MAPK8_ST	P30305	CDC25B	P45983	MAPK8	S42	R45W	45	Missense	distal	3	no	8.088	8.138	EPSD	ICGC;COSMIC	2.638	Up-regulation
CMGC_MAPK_JNK_MAPK8_ST	P30305	CDC25B	P45983	MAPK8	S50	R45W	45	Missense	distal	-5	no	9.900	9.946	EPSD	ICGC;COSMIC	2.638	Up-regulation
CMGC_MAPK_JNK_MAPK8_ST	P30305	CDC25B	P45983	MAPK8	T69	S67R	67	Missense	proximal	-2	no	7.377	7.299	EPSD	ICGC	2.638	Down-regulation
CMGC_MAPK_JNK_MAPK8_ST	P30305	CDC25B	P45983	MAPK8	S115	D120Y	120	Missense	distal	5	no	7.331	7.391	EPSD	ICGC	2.638	Up-regulation
CMGC_MAPK_JNK_MAPK8_ST	P30305	CDC25B	P45983	MAPK8	S117	D120Y	120	Missense	distal	3	no	7.637	7.798	EPSD	ICGC	2.638	Up-regulation
CMGC_MAPK_JNK_MAPK8_ST	P30305	CDC25B	P45983	MAPK8	S238	P232T	232	Missense	distal	-6	no	7.003	6.940	EPSD	ICGC;COSMIC	2.638	Down-regulation
CMGC_MAPK_JNK_MAPK8_ST	P30305	CDC25B	P45983	MAPK8	S249	E247D	247	Missense	proximal	-2	no	8.352	8.298	EPSD	ICGC;COSMIC	2.638	Down-regulation
CMGC_MAPK_JNK_MAPK8_ST	P30305	CDC25B	P45983	MAPK8	S321	M324R	324	Missense	distal	3	no	9.454	9.431	EPSD	ICGC;COSMIC	2.638	Down-regulation
CMGC_MAPK_JNK_MAPK8_ST	P30305	CDC25B	P45983	MAPK8	S321	R320C	320	Missense	proximal	-1	no	9.454	9.460	EPSD	ICGC	2.638	Up-regulation
CMGC_MAPK_JNK_MAPK8_ST	P30305	CDC25B	P45983	MAPK8	S470	E464Q	464	Missense	distal	-6	no	8.647	8.708	EPSD	ICGC;COSMIC	2.638	Up-regulation
CMGC_MAPK_JNK_MAPK8_ST	Q13043	STK4	P45983	MAPK8	S82	V85L	85	Missense	distal	3	no	7.389	7.370	PhosphoSitePlus	ICGC	2.638	Down-regulation
CMGC_MAPK_JNK_MAPK8_ST	Q13043	STK4	P45983	MAPK8	S265	E267D	267	Missense	proximal	2	no	8.206	8.006	EPSD	ICGC	2.638	Down-regulation
CMGC_MAPK_JNK_MAPK8_ST	Q07820	MCL1	P45983	MAPK8	T92	V86L	86	Missense	distal	-6	no	7.127	7.102	EPSD	ICGC	2.638	Down-regulation
CMGC_MAPK_JNK_MAPK8_ST	Q07820	MCL1	P45983	MAPK8	T92	E85D	85	Missense	distal	-7	no	7.127	7.135	EPSD	ICGC	2.638	Up-regulation
CMGC_MAPK_JNK_MAPK8_ST	Q07820	MCL1	P45983	MAPK8	T92	A94T	94	Missense	proximal	2	no	7.127	7.105	EPSD	ICGC	2.638	Down-regulation
CMGC_MAPK_JNK_MAPK8_ST	Q07820	MCL1	P45983	MAPK8	T92	R95S	95	Missense	distal	3	no	7.127	6.944	EPSD	ICGC;COSMIC	2.638	Down-regulation
CMGC_MAPK_JNK_MAPK8_ST	Q07820	MCL1	P45983	MAPK8	T92	T92P	92	Missense	central	0	yes	7.127	0.000	EPSD	ICGC;COSMIC	2.638	Loss
CMGC_MAPK_JNK_MAPK8_ST	Q07820	MCL1	P45983	MAPK8	S121	I119V	119	Missense	proximal	-2	no	6.612	6.474	EPSD;PhosphoSitePlus	ICGC;COSMIC	2.638	Down-regulation
CMGC_MAPK_JNK_MAPK8_ST	Q07820	MCL1	P45983	MAPK8	S121	E125D	125	Missense	distal	4	no	6.612	6.460	EPSD;PhosphoSitePlus	ICGC;COSMIC	2.638	Down-regulation
CMGC_MAPK_JNK_MAPK8_ST	Q07820	MCL1	P45983	MAPK8	T163	T156A	156	Missense	distal	-7	no	8.911	8.910	EPSD;PhosphoSitePlus	ICGC	2.638	Down-regulation
CMGC_MAPK_JNK_MAPK8_ST	Q07820	MCL1	P45983	MAPK8	T163	P161S	161	Missense	proximal	-2	no	8.911	8.805	EPSD;PhosphoSitePlus	ICGC;COSMIC	2.638	Down-regulation
CMGC_MAPK_JNK_MAPK8_ST	Q07820	MCL1	P45983	MAPK8	T163	P166Q	166	Missense	distal	3	no	8.911	8.842	EPSD;PhosphoSitePlus	ICGC;COSMIC	2.638	Down-regulation
CMGC_MAPK_JNK_MAPK8_ST	P30307	CDC25C	P45983	MAPK8	T48	G55S	55	Missense	distal	7	no	7.132	7.068	EPSD	ICGC;COSMIC	2.638	Down-regulation
CMGC_MAPK_JNK_MAPK8_ST	P30307	CDC25C	P45983	MAPK8	S61	G55S	55	Missense	distal	-6	no	3.281	3.130	EPSD	ICGC;COSMIC	2.638	Down-regulation
CMGC_MAPK_JNK_MAPK8_ST	P30307	CDC25C	P45983	MAPK8	S61	A58E	58	Missense	distal	-3	no	3.281	3.298	EPSD	ICGC	2.638	Up-regulation
CMGC_MAPK_JNK_MAPK8_ST	P30307	CDC25C	P45983	MAPK8	T67	R70C	70	Missense	distal	3	no	7.370	7.352	EPSD	ICGC;COSMIC	2.638	Down-regulation
CMGC_MAPK_JNK_MAPK8_ST	P30307	CDC25C	P45983	MAPK8	T130	R136H	136	Missense	distal	6	no	6.005	6.018	EPSD	ICGC;COSMIC;GDSC	2.638	Up-regulation
CMGC_MAPK_JNK_MAPK8_ST	P30307	CDC25C	P45983	MAPK8	T130	R136S	136	Missense	distal	6	no	6.005	6.066	EPSD	ICGC;COSMIC	2.638	Up-regulation
CMGC_MAPK_JNK_MAPK8_ST	P30307	CDC25C	P45983	MAPK8	S168	T172A	172	Missense	distal	4	no	8.423	8.472	PhosphoSitePlus	ICGC;COSMIC	2.638	Up-regulation
CMGC_MAPK_JNK_MAPK8_ST	P30307	CDC25C	P45983	MAPK8	S214	E219D	219	Missense	distal	5	no	8.343	8.401	EPSD	ICGC;COSMIC	2.638	Up-regulation
CMGC_MAPK_JNK_MAPK8_ST	Q8WYQ5	DGCR8	P45983	MAPK8	S6	P11L	11	Missense	distal	5	no	8.332	8.330	EPSD	ICGC;COSMIC	2.638	Down-regulation
CMGC_MAPK_JNK_MAPK8_ST	Q8WYQ5	DGCR8	P45983	MAPK8	S8	P11L	11	Missense	distal	3	no	7.596	7.698	EPSD	ICGC;COSMIC	2.638	Up-regulation
CMGC_MAPK_JNK_MAPK8_ST	Q8WYQ5	DGCR8	P45983	MAPK8	S8	A15T	15	Missense	distal	7	no	7.596	7.599	EPSD	ICGC;COSMIC	2.638	Up-regulation
CMGC_MAPK_JNK_MAPK8_ST	Q8WYQ5	DGCR8	P45983	MAPK8	S35	Q34K	34	Missense	proximal	-1	no	7.738	7.750	EPSD	ICGC	2.638	Up-regulation
CMGC_MAPK_JNK_MAPK8_ST	Q8WYQ5	DGCR8	P45983	MAPK8	S35	R32H	32	Missense	distal	-3	no	7.738	7.775	EPSD	ICGC;COSMIC	2.638	Up-regulation
CMGC_MAPK_JNK_MAPK8_ST	Q8WYQ5	DGCR8	P45983	MAPK8	S35	R32C	32	Missense	distal	-3	no	7.738	7.787	EPSD	ICGC;COSMIC	2.638	Up-regulation
CMGC_MAPK_JNK_MAPK8_ST	Q8WYQ5	DGCR8	P45983	MAPK8	S95	P89T	89	Missense	distal	-6	no	10.575	10.511	EPSD	ICGC;COSMIC	2.638	Down-regulation
CMGC_MAPK_JNK_MAPK8_ST	Q8WYQ5	DGCR8	P45983	MAPK8	S109	L115F	115	Missense	distal	6	no	6.871	6.874	EPSD	ICGC	2.638	Up-regulation
CMGC_MAPK_JNK_MAPK8_ST	Q8WYQ5	DGCR8	P45983	MAPK8	S109	P110H	110	Missense	proximal	1	no	6.871	-1.044	EPSD	ICGC	2.638	Loss
CMGC_MAPK_JNK_MAPK8_ST	Q8WYQ5	DGCR8	P45983	MAPK8	S153	V155F	155	Missense	proximal	2	no	7.348	7.370	PhosphoSitePlus	ICGC	2.638	Up-regulation
CMGC_MAPK_JNK_MAPK8_ST	Q8WYQ5	DGCR8	P45983	MAPK8	S367	S368I	368	Missense	proximal	1	no	1.801	3.656	EPSD	ICGC	2.638	Gain
CMGC_MAPK_JNK_MAPK8_ST	Q8WYQ5	DGCR8	P45983	MAPK8	T371	S368I	368	Missense	distal	-3	no	6.340	6.181	EPSD	ICGC	2.638	Down-regulation
CMGC_MAPK_JNK_MAPK8_ST	Q8WYQ5	DGCR8	P45983	MAPK8	S377	V379F	379	Missense	proximal	2	no	7.335	7.356	EPSD	ICGC	2.638	Up-regulation
CMGC_MAPK_JNK_MAPK8_ST	Q8N122	RPTOR	P45983	MAPK8	S8	M5I	5	Missense	distal	-3	no	6.626	6.792	EPSD	ICGC;COSMIC	2.638	Up-regulation
CMGC_MAPK_JNK_MAPK8_ST	Q8N122	RPTOR	P45983	MAPK8	S8	G12V	12	Missense	distal	4	no	6.626	6.450	EPSD	ICGC	2.638	Down-regulation
CMGC_MAPK_JNK_MAPK8_ST	Q8N122	RPTOR	P45983	MAPK8	S8	G14R	14	Missense	distal	6	no	6.626	6.623	EPSD	ICGC;COSMIC	2.638	Down-regulation
CMGC_MAPK_JNK_MAPK8_ST	Q8N122	RPTOR	P45983	MAPK8	S696	T699M	699	Missense	distal	3	no	7.020	7.197	PhosphoSitePlus;EPSD	ICGC;COSMIC	2.638	Up-regulation
CMGC_MAPK_JNK_MAPK8_ST	Q8N122	RPTOR	P45983	MAPK8	T706	T699M	699	Missense	distal	-7	no	8.509	8.523	EPSD;PhosphoSitePlus	ICGC;COSMIC	2.638	Up-regulation
CMGC_MAPK_JNK_MAPK8_ST	Q8N122	RPTOR	P45983	MAPK8	S859	T853M	853	Missense	distal	-6	no	4.390	4.530	EPSD	ICGC;COSMIC	2.638	Up-regulation
CMGC_MAPK_JNK_MAPK8_ST	Q8N122	RPTOR	P45983	MAPK8	S881	S887N	887	Missense	distal	6	no	3.451	3.386	EPSD	ICGC;COSMIC	2.638	Down-regulation
CMGC_MAPK_JNK_MAPK8_ST	Q8N122	RPTOR	P45983	MAPK8	S898	D900E	900	Missense	proximal	2	no	3.303	3.503	EPSD	ICGC;COSMIC	2.638	Up-regulation
CMGC_MAPK_JNK_MAPK8_ST	Q8N122	RPTOR	P45983	MAPK8	T917	A914V	914	Missense	distal	-3	no	6.949	6.519	EPSD	ICGC;COSMIC	2.638	Down-regulation
CMGC_MAPK_JNK_MAPK8_ST	P04637	TP53	P45983	MAPK8	S20	W23C	23	Missense	distal	3	no	4.275	4.207	PhosphoSitePlus;EPSD	ICGC;COSMIC	2.638	Down-regulation
CMGC_MAPK_JNK_MAPK8_ST	P04637	TP53	P45983	MAPK8	S33	P34L	34	Missense	proximal	1	no	7.176	-0.396	EPSD	ICGC;COSMIC	2.638	Loss
CMGC_MAPK_JNK_MAPK8_ST	P04637	TP53	P45983	MAPK8	S33	S33F	33	Missense	central	0	yes	7.176	0.000	EPSD	ICGC;COSMIC	2.638	Loss
CMGC_MAPK_JNK_MAPK8_ST	P04637	TP53	P45983	MAPK8	S33	N30I	30	Missense	distal	-3	no	7.176	7.370	EPSD	ICGC	2.638	Up-regulation
CMGC_MAPK_JNK_MAPK8_ST	P04637	TP53	P45983	MAPK8	S46	D48G	48	Missense	proximal	2	no	8.038	7.972	EPSD	ICGC;COSMIC	2.638	Down-regulation
CMGC_MAPK_JNK_MAPK8_ST	P04637	TP53	P45983	MAPK8	S46	Q52K	52	Missense	distal	6	no	8.038	8.070	EPSD	ICGC	2.638	Up-regulation
CMGC_MAPK_JNK_MAPK8_ST	P04637	TP53	P45983	MAPK8	T81	A88D	88	Missense	distal	7	no	7.682	7.717	EPSD;PhosphoSitePlus	ICGC	2.638	Up-regulation
CMGC_MAPK_JNK_MAPK8_ST	P04637	TP53	P45983	MAPK8	T81	P87Q	87	Missense	distal	6	no	7.682	7.692	EPSD;PhosphoSitePlus	ICGC;COSMIC	2.638	Up-regulation
CMGC_MAPK_JNK_MAPK8_ST	P04637	TP53	P45983	MAPK8	S127	T125R	125	Missense	proximal	-2	no	8.358	8.254	EPSD	ICGC;COSMIC	2.638	Down-regulation
CMGC_MAPK_JNK_MAPK8_ST	P04637	TP53	P45983	MAPK8	S127	F134C	134	Missense	distal	7	no	8.358	8.335	EPSD	ICGC;COSMIC;CCLE	2.638	Down-regulation
CMGC_MAPK_JNK_MAPK8_ST	P04637	TP53	P45983	MAPK8	S127	C124G	124	Missense	distal	-3	no	8.358	8.332	EPSD	ICGC;COSMIC	2.638	Down-regulation
CMGC_MAPK_JNK_MAPK8_ST	P04637	TP53	P45983	MAPK8	S127	C124R	124	Missense	distal	-3	no	8.358	8.308	EPSD	ICGC;COSMIC;GDSC;CCLE	2.638	Down-regulation
CMGC_MAPK_JNK_MAPK8_ST	P04637	TP53	P45983	MAPK8	S127	L130H	130	Missense	distal	3	no	8.358	8.294	EPSD	ICGC;COSMIC	2.638	Down-regulation
CMGC_MAPK_JNK_MAPK8_ST	P04637	TP53	P45983	MAPK8	S127	T125A	125	Missense	proximal	-2	no	8.358	8.387	EPSD	ICGC;COSMIC	2.638	Up-regulation
CMGC_MAPK_JNK_MAPK8_ST	P04637	TP53	P45983	MAPK8	S127	K120N	120	Missense	distal	-7	no	8.358	8.376	EPSD	ICGC;COSMIC;GDSC;CCLE	2.638	Up-regulation
CMGC_MAPK_JNK_MAPK8_ST	P04637	TP53	P45983	MAPK8	S127	N131Y	131	Missense	distal	4	no	8.358	8.280	EPSD	ICGC;COSMIC	2.638	Down-regulation
CMGC_MAPK_JNK_MAPK8_ST	P04637	TP53	P45983	MAPK8	S127	K120M	120	Missense	distal	-7	no	8.358	8.377	EPSD	ICGC;COSMIC	2.638	Up-regulation
CMGC_MAPK_JNK_MAPK8_ST	P04637	TP53	P45983	MAPK8	S127	K132M	132	Missense	distal	5	no	8.358	8.449	EPSD	ICGC;COSMIC;CCLE	2.638	Up-regulation
CMGC_MAPK_JNK_MAPK8_ST	P04637	TP53	P45983	MAPK8	S127	M133T	133	Missense	distal	6	no	8.358	8.418	EPSD	ICGC;COSMIC	2.638	Up-regulation
CMGC_MAPK_JNK_MAPK8_ST	P04637	TP53	P45983	MAPK8	S127	K120R	120	Missense	distal	-7	no	8.358	8.375	EPSD	ICGC;COSMIC	2.638	Up-regulation
CMGC_MAPK_JNK_MAPK8_ST	P04637	TP53	P45983	MAPK8	S127	C124Y	124	Missense	distal	-3	no	8.358	8.129	EPSD	ICGC;COSMIC	2.638	Down-regulation
CMGC_MAPK_JNK_MAPK8_ST	P04637	TP53	P45983	MAPK8	T150	R156L	156	Missense	distal	6	no	6.536	6.525	EPSD	ICGC;COSMIC	2.638	Down-regulation
CMGC_MAPK_JNK_MAPK8_ST	P04637	TP53	P45983	MAPK8	T150	L145Q	145	Missense	distal	-5	no	6.536	6.154	EPSD	ICGC;COSMIC	2.638	Down-regulation
CMGC_MAPK_JNK_MAPK8_ST	P04637	TP53	P45983	MAPK8	T150	P152R	152	Missense	proximal	2	no	6.536	6.480	EPSD	ICGC;COSMIC	2.638	Down-regulation
CMGC_MAPK_JNK_MAPK8_ST	P04637	TP53	P45983	MAPK8	T150	G154S	154	Missense	distal	4	no	6.536	6.880	EPSD	ICGC;COSMIC	2.638	Up-regulation
CMGC_MAPK_JNK_MAPK8_ST	P04637	TP53	P45983	MAPK8	T150	V157A	157	Missense	distal	7	no	6.536	6.457	EPSD	ICGC;COSMIC	2.638	Down-regulation
CMGC_MAPK_JNK_MAPK8_ST	P04637	TP53	P45983	MAPK8	T150	P151F	151	Missense	proximal	1	no	6.536	-1.636	EPSD	ICGC;COSMIC	2.638	Loss
CMGC_MAPK_JNK_MAPK8_ST	P04637	TP53	P45983	MAPK8	T150	V147G	147	Missense	distal	-3	no	6.536	6.649	EPSD	ICGC;COSMIC;GDSC;CCLE	2.638	Up-regulation
CMGC_MAPK_JNK_MAPK8_ST	P04637	TP53	P45983	MAPK8	S183	C182W	182	Missense	proximal	-1	no	3.143	3.133	EPSD	ICGC;COSMIC	2.638	Down-regulation
CMGC_MAPK_JNK_MAPK8_ST	P04637	TP53	P45983	MAPK8	S183	H178D	178	Missense	distal	-5	no	3.143	3.059	EPSD	ICGC;COSMIC;CCLE	2.638	Down-regulation
CMGC_MAPK_JNK_MAPK8_ST	P04637	TP53	P45983	MAPK8	S183	D184H	184	Missense	proximal	1	no	3.143	1.533	EPSD	ICGC;COSMIC	2.638	Loss
CMGC_MAPK_JNK_MAPK8_ST	P04637	TP53	P45983	MAPK8	S183	A189T	189	Missense	distal	6	no	3.143	3.144	EPSD	ICGC;COSMIC	2.638	Up-regulation
CMGC_MAPK_JNK_MAPK8_ST	P04637	TP53	P45983	MAPK8	S183	P190T	190	Missense	distal	7	no	3.143	3.113	EPSD	ICGC;COSMIC	2.638	Down-regulation
CMGC_MAPK_JNK_MAPK8_ST	P04637	TP53	P45983	MAPK8	S183	P190S	190	Missense	distal	7	no	3.143	3.105	EPSD	ICGC;COSMIC	2.638	Down-regulation
CMGC_MAPK_JNK_MAPK8_ST	P04637	TP53	P45983	MAPK8	S183	A189D	189	Missense	distal	6	no	3.143	3.113	EPSD	ICGC;COSMIC	2.638	Down-regulation
CMGC_MAPK_JNK_MAPK8_ST	P04637	TP53	P45983	MAPK8	S183	E180D	180	Missense	distal	-3	no	3.143	2.904	EPSD	ICGC;COSMIC	2.638	Down-regulation
CMGC_MAPK_JNK_MAPK8_ST	P04637	TP53	P45983	MAPK8	S183	C176G	176	Missense	distal	-7	no	3.143	3.145	EPSD	ICGC;COSMIC	2.638	Up-regulation
CMGC_MAPK_JNK_MAPK8_ST	P04637	TP53	P45983	MAPK8	S315	T312I	312	Missense	distal	-3	no	8.332	8.190	EPSD	ICGC;COSMIC	2.638	Down-regulation
CMGC_MAPK_JNK_MAPK8_ST	P04637	TP53	P45983	MAPK8	S315	P322T	322	Missense	distal	7	no	8.332	8.301	EPSD	ICGC	2.638	Down-regulation
CMGC_MAPK_JNK_MAPK8_ST	P04637	TP53	P45983	MAPK8	S376	T377P	377	Missense	proximal	1	no	1.288	8.275	EPSD	ICGC;COSMIC	2.638	Gain
CMGC_MAPK_JNK_MAPK8_ST	Q96FI4	NEIL1	P45983	MAPK8	S61	A66V	66	Missense	distal	5	no	8.363	8.435	EPSD;PhosphoSitePlus	ICGC;COSMIC	2.638	Up-regulation
CMGC_MAPK_JNK_MAPK8_ST	Q96FI4	NEIL1	P45983	MAPK8	S61	R57L	57	Missense	distal	-4	no	8.363	8.172	EPSD;PhosphoSitePlus	ICGC	2.638	Down-regulation
CMGC_MAPK_JNK_MAPK8_ST	Q96FI4	NEIL1	P45983	MAPK8	S61	P68S	68	Missense	distal	7	no	8.363	8.324	EPSD;PhosphoSitePlus	ICGC;COSMIC	2.638	Down-regulation
CMGC_MAPK_JNK_MAPK8_ST	Q96FI4	NEIL1	P45983	MAPK8	S207	Q202H	202	Missense	distal	-5	no	9.638	9.858	PhosphoSitePlus;EPSD	ICGC;COSMIC	2.638	Up-regulation
CMGC_MAPK_JNK_MAPK8_ST	Q96FI4	NEIL1	P45983	MAPK8	S306	R310K	310	Missense	distal	4	no	8.823	9.218	EPSD;PhosphoSitePlus	ICGC	2.638	Up-regulation
CMGC_MAPK_JNK_MAPK8_ST	Q96FI4	NEIL1	P45983	MAPK8	S306	K299R	299	Missense	distal	-7	no	8.823	8.840	EPSD;PhosphoSitePlus	ICGC	2.638	Up-regulation
CMGC_MAPK_JNK_MAPK8_ST	P55957	BID	P45983	MAPK8	S78	E73D	73	Missense	distal	-5	no	2.438	2.680	EPSD	ICGC	2.638	Gain
CMGC_MAPK_JNK_MAPK8_ST	P29966	MARCKS	P45983	MAPK8	S27	G20V	20	Missense	distal	-7	no	9.143	9.148	EPSD	ICGC;COSMIC	2.638	Up-regulation
CMGC_MAPK_JNK_MAPK8_ST	P29966	MARCKS	P45983	MAPK8	S27	G33R	33	Missense	distal	6	no	9.143	9.139	EPSD	ICGC	2.638	Down-regulation
CMGC_MAPK_JNK_MAPK8_ST	P29966	MARCKS	P45983	MAPK8	S81	E86K	86	Missense	distal	5	no	7.965	7.956	EPSD	ICGC	2.638	Down-regulation
CMGC_MAPK_JNK_MAPK8_ST	P29966	MARCKS	P45983	MAPK8	S118	S118L	118	Missense	central	0	yes	7.692	0.000	EPSD	ICGC;COSMIC	2.638	Loss
CMGC_MAPK_JNK_MAPK8_ST	P29966	MARCKS	P45983	MAPK8	S118	E125G	125	Missense	distal	7	no	7.692	7.757	EPSD	ICGC;COSMIC	2.638	Up-regulation
CMGC_MAPK_JNK_MAPK8_ST	P29966	MARCKS	P45983	MAPK8	S135	S132L	132	Missense	distal	-3	no	8.101	7.759	EPSD	ICGC;COSMIC	2.638	Down-regulation
CMGC_MAPK_JNK_MAPK8_ST	P29966	MARCKS	P45983	MAPK8	T143	P144S	144	Missense	proximal	1	no	6.452	-1.277	EPSD	ICGC;COSMIC	2.638	Loss
CMGC_MAPK_JNK_MAPK8_ST	P29966	MARCKS	P45983	MAPK8	S145	P144S	144	Missense	proximal	-1	no	8.513	8.523	EPSD	ICGC;COSMIC	2.638	Up-regulation
CMGC_MAPK_JNK_MAPK8_ST	P29966	MARCKS	P45983	MAPK8	T150	P144S	144	Missense	distal	-6	no	6.660	6.571	EPSD	ICGC;COSMIC	2.638	Down-regulation
CMGC_MAPK_JNK_MAPK8_ST	Q8N6T7	SIRT6	P45983	MAPK8	T294	T294P	294	Missense	central	0	yes	9.150	0.000	EPSD	ICGC;COSMIC	2.638	Loss
CMGC_MAPK_JNK_MAPK8_ST	Q8N6T7	SIRT6	P45983	MAPK8	T294	R291P	291	Missense	distal	-3	no	9.150	9.292	EPSD	ICGC;COSMIC	2.638	Up-regulation
CMGC_MAPK_JNK_MAPK8_ST	Q8N6T7	SIRT6	P45983	MAPK8	T294	E301D	301	Missense	distal	7	no	9.150	9.190	EPSD	ICGC;COSMIC	2.638	Up-regulation
CMGC_MAPK_JNK_MAPK8_ST	Q8N6T7	SIRT6	P45983	MAPK8	T294	L289P	289	Missense	distal	-5	no	9.150	8.790	EPSD	ICGC;COSMIC	2.638	Down-regulation
CMGC_MAPK_JNK_MAPK8_ST	Q8N6T7	SIRT6	P45983	MAPK8	S303	E301D	301	Missense	proximal	-2	no	7.344	7.290	EPSD	ICGC;COSMIC	2.638	Down-regulation
CMGC_MAPK_JNK_MAPK8_ST	Q8N6T7	SIRT6	P45983	MAPK8	S330	P336S	336	Missense	distal	6	no	9.096	9.120	EPSD	ICGC	2.638	Up-regulation
CMGC_MAPK_JNK_MAPK8_ST	Q8N6T7	SIRT6	P45983	MAPK8	S330	R335Q	335	Missense	distal	5	no	9.096	9.044	EPSD	ICGC	2.638	Down-regulation
CMGC_MAPK_JNK_MAPK8_ST	Q8N6T7	SIRT6	P45983	MAPK8	S330	H323Q	323	Missense	distal	-7	no	9.096	9.088	EPSD	ICGC	2.638	Down-regulation
CMGC_MAPK_JNK_MAPK8_ST	Q8N6T7	SIRT6	P45983	MAPK8	S338	P336S	336	Missense	proximal	-2	no	9.406	9.301	EPSD	ICGC	2.638	Down-regulation
CMGC_MAPK_JNK_MAPK8_ST	Q8N6T7	SIRT6	P45983	MAPK8	S338	R335Q	335	Missense	distal	-3	no	9.406	9.605	EPSD	ICGC	2.638	Up-regulation
CMGC_MAPK_JNK_MAPK8_ST	Q8N6T7	SIRT6	P45983	MAPK8	S338	H342N	342	Missense	distal	4	no	9.406	9.286	EPSD	ICGC	2.638	Down-regulation
CMGC_MAPK_JNK_MAPK8_ST	Q8N6T7	SIRT6	P45983	MAPK8	S338	S338R	338	Missense	central	0	yes	9.406	0.000	EPSD	ICGC	2.638	Loss
CMGC_MAPK_JNK_MAPK8_ST	Q8N6T7	SIRT6	P45983	MAPK8	S338	P339T	339	Missense	proximal	1	no	9.406	2.419	EPSD	ICGC	2.638	Loss
CMGC_MAPK_JNK_MAPK8_ST	Q96LC9	BMF	P45983	MAPK8	T72	S77F	77	Missense	distal	5	no	2.877	2.953	EPSD	ICGC	2.638	Up-regulation
CMGC_MAPK_JNK_MAPK8_ST	Q96LC9	BMF	P45983	MAPK8	S74	S77F	77	Missense	distal	3	no	7.205	7.424	PhosphoSitePlus	ICGC	2.638	Up-regulation
CMGC_MAPK_JNK_MAPK8_ST	Q96LC9	BMF	P45983	MAPK8	S77	S77F	77	Missense	central	0	yes	8.228	0.000	EPSD	ICGC	2.638	Loss
CMGC_MAPK_JNK_MAPK8_ST	Q7KZF4	SND1	P45983	MAPK8	T98	G92E	92	Missense	distal	-6	no	3.055	2.897	EPSD	ICGC	2.638	Down-regulation
CMGC_MAPK_JNK_MAPK8_ST	Q7KZF4	SND1	P45983	MAPK8	T179	D175N	175	Missense	distal	-4	no	3.146	2.839	EPSD	ICGC;COSMIC	2.638	Down-regulation
CMGC_MAPK_JNK_MAPK8_ST	Q7KZF4	SND1	P45983	MAPK8	T179	R174W	174	Missense	distal	-5	no	3.146	3.192	EPSD	ICGC;COSMIC	2.638	Up-regulation
CMGC_MAPK_JNK_MAPK8_ST	Q7KZF4	SND1	P45983	MAPK8	T179	L176R	176	Missense	distal	-3	no	3.146	3.183	EPSD	ICGC;COSMIC	2.638	Up-regulation
CMGC_MAPK_JNK_MAPK8_ST	Q7KZF4	SND1	P45983	MAPK8	T240	E242G	242	Missense	proximal	2	no	7.851	7.585	EPSD	ICGC	2.638	Down-regulation
CMGC_MAPK_JNK_MAPK8_ST	Q7KZF4	SND1	P45983	MAPK8	S426	S426I	426	Missense	central	0	yes	9.196	0.000	EPSD	ICGC	2.638	Loss
CMGC_MAPK_JNK_MAPK8_ST	Q7KZF4	SND1	P45983	MAPK8	S645	A650T	650	Missense	distal	5	no	2.761	2.759	EPSD	ICGC;COSMIC	2.638	Down-regulation
CMGC_MAPK_JNK_MAPK8_ST	Q7KZF4	SND1	P45983	MAPK8	S645	A649V	649	Missense	distal	4	no	2.761	2.243	EPSD	ICGC;COSMIC	2.638	Loss
CMGC_MAPK_JNK_MAPK8_ST	Q7KZF4	SND1	P45983	MAPK8	S645	A646S	646	Missense	proximal	1	no	2.761	1.380	EPSD	ICGC	2.638	Loss
CMGC_MAPK_JNK_MAPK8_ST	Q7KZF4	SND1	P45983	MAPK8	S681	E677D	677	Missense	distal	-4	no	3.232	2.809	EPSD	ICGC;COSMIC	2.638	Down-regulation
CMGC_MAPK_JNK_MAPK8_ST	Q7KZF4	SND1	P45983	MAPK8	S681	P684R	684	Missense	distal	3	no	3.232	3.289	EPSD	ICGC	2.638	Up-regulation
CMGC_MAPK_JNK_MAPK8_ST	Q7KZF4	SND1	P45983	MAPK8	S755	S755Y	755	Missense	central	0	yes	9.308	0.000	EPSD	ICGC	2.638	Loss
CMGC_MAPK_JNK_MAPK8_ST	Q7KZF4	SND1	P45983	MAPK8	S781	G778V	778	Missense	distal	-3	no	8.561	8.448	EPSD	ICGC;COSMIC	2.638	Down-regulation
CMGC_MAPK_JNK_MAPK8_ST	Q7KZF4	SND1	P45983	MAPK8	S781	L780V	780	Missense	proximal	-1	no	8.561	8.556	EPSD	ICGC;COSMIC	2.638	Down-regulation
CMGC_MAPK_JNK_MAPK8_ST	Q7KZF4	SND1	P45983	MAPK8	S781	R787L	787	Missense	distal	6	no	8.561	8.550	EPSD	ICGC;COSMIC	2.638	Down-regulation
CMGC_MAPK_JNK_MAPK8_ST	P05787	KRT8	P45983	MAPK8	S35	S36W	36	Missense	proximal	1	no	2.103	4.158	EPSD	ICGC	2.638	Gain
CMGC_MAPK_JNK_MAPK8_ST	P05787	KRT8	P45983	MAPK8	S417	S410G	410	Missense	distal	-7	no	2.996	3.010	EPSD	ICGC;COSMIC	2.638	Up-regulation
CMGC_MAPK_JNK_MAPK8_ST	P05787	KRT8	P45983	MAPK8	S417	S424I	424	Missense	distal	7	no	2.996	3.036	EPSD	ICGC	2.638	Up-regulation
CMGC_MAPK_JNK_MAPK8_ST	P05787	KRT8	P45983	MAPK8	S432	L435I	435	Missense	distal	3	no	7.697	7.594	EPSD;PhosphoSitePlus	ICGC	2.638	Down-regulation
CMGC_MAPK_JNK_MAPK8_ST	P14618	PKM	P45983	MAPK8	S37	D34E	34	Missense	distal	-3	no	7.425	7.664	EPSD	ICGC	2.638	Up-regulation
CMGC_MAPK_JNK_MAPK8_ST	P14618	PKM	P45983	MAPK8	S37	P38T	38	Missense	proximal	1	no	7.425	0.438	EPSD	ICGC	2.638	Loss
CMGC_MAPK_JNK_MAPK8_ST	P14618	PKM	P45983	MAPK8	T41	D34E	34	Missense	distal	-7	no	3.502	3.493	EPSD	ICGC	2.638	Down-regulation
CMGC_MAPK_JNK_MAPK8_ST	P14618	PKM	P45983	MAPK8	T41	P38T	38	Missense	distal	-3	no	3.502	3.646	EPSD	ICGC	2.638	Up-regulation
CMGC_MAPK_JNK_MAPK8_ST	P14618	PKM	P45983	MAPK8	S406	E410K	410	Missense	distal	4	no	4.057	4.138	EPSD	ICGC;COSMIC	2.638	Up-regulation
CMGC_MAPK_JNK_MAPK8_ST	O95644	NFATC1	P45983	MAPK8	S117	S124L	124	Missense	distal	7	no	7.644	7.722	EPSD	ICGC;COSMIC	2.638	Up-regulation
CMGC_MAPK_JNK_MAPK8_ST	O95644	NFATC1	P45983	MAPK8	S117	R119H	119	Missense	proximal	2	no	7.644	7.702	EPSD	ICGC;COSMIC	2.638	Up-regulation
CMGC_MAPK_JNK_MAPK8_ST	O95644	NFATC1	P45983	MAPK8	S117	E121K	121	Missense	distal	4	no	7.644	7.725	EPSD	ICGC;COSMIC	2.638	Up-regulation
CMGC_MAPK_JNK_MAPK8_ST	O95644	NFATC1	P45983	MAPK8	S151	T154M	154	Missense	distal	3	no	8.781	8.958	EPSD	ICGC;COSMIC;CCLE	2.638	Up-regulation
CMGC_MAPK_JNK_MAPK8_ST	O95644	NFATC1	P45983	MAPK8	S151	S151P	151	Missense	central	0	yes	8.781	0.000	EPSD	ICGC;COSMIC	2.638	Loss
CMGC_MAPK_JNK_MAPK8_ST	O95644	NFATC1	P45983	MAPK8	S151	S158R	158	Missense	distal	7	no	8.781	8.844	EPSD	ICGC;COSMIC	2.638	Up-regulation
CMGC_MAPK_JNK_MAPK8_ST	O95644	NFATC1	P45983	MAPK8	S151	S151C	151	Missense	central	0	yes	8.781	0.000	EPSD	ICGC;COSMIC	2.638	Loss
CMGC_MAPK_JNK_MAPK8_ST	O95644	NFATC1	P45983	MAPK8	S151	R150L	150	Missense	proximal	-1	no	8.781	8.777	EPSD	ICGC	2.638	Down-regulation
CMGC_MAPK_JNK_MAPK8_ST	O95644	NFATC1	P45983	MAPK8	S151	P152L	152	Missense	proximal	1	no	8.781	1.208	EPSD	ICGC;COSMIC	2.638	Loss
CMGC_MAPK_JNK_MAPK8_ST	O95644	NFATC1	P45983	MAPK8	S151	P146S	146	Missense	distal	-5	no	8.781	8.669	EPSD	ICGC;COSMIC	2.638	Down-regulation
CMGC_MAPK_JNK_MAPK8_ST	O95644	NFATC1	P45983	MAPK8	S151	V144I	144	Missense	distal	-7	no	8.781	8.771	EPSD	ICGC;COSMIC	2.638	Down-regulation
CMGC_MAPK_JNK_MAPK8_ST	O95644	NFATC1	P45983	MAPK8	S151	T156M	156	Missense	distal	5	no	8.781	8.846	EPSD	ICGC;COSMIC	2.638	Up-regulation
CMGC_MAPK_JNK_MAPK8_ST	O95644	NFATC1	P45983	MAPK8	S151	R150W	150	Missense	proximal	-1	no	8.781	8.777	EPSD	ICGC	2.638	Down-regulation
CMGC_MAPK_JNK_MAPK8_ST	O95644	NFATC1	P45983	MAPK8	S172	A174T	174	Missense	proximal	2	no	9.471	9.449	PhosphoSitePlus	ICGC;COSMIC	2.638	Down-regulation
CMGC_MAPK_JNK_MAPK8_ST	O95644	NFATC1	P45983	MAPK8	S172	L177M	177	Missense	distal	5	no	9.471	9.461	PhosphoSitePlus	ICGC;COSMIC	2.638	Down-regulation
CMGC_MAPK_JNK_MAPK8_ST	O95644	NFATC1	P45983	MAPK8	S172	L171P	171	Missense	proximal	-1	no	9.471	9.489	PhosphoSitePlus	ICGC	2.638	Up-regulation
CMGC_MAPK_JNK_MAPK8_ST	O95644	NFATC1	P45983	MAPK8	S172	A174V	174	Missense	proximal	2	no	9.471	9.153	PhosphoSitePlus	ICGC	2.638	Down-regulation
CMGC_MAPK_JNK_MAPK8_ST	O95644	NFATC1	P45983	MAPK8	S172	S176N	176	Missense	distal	4	no	9.471	9.022	PhosphoSitePlus	ICGC	2.638	Down-regulation
CMGC_MAPK_JNK_MAPK8_ST	O95644	NFATC1	P45983	MAPK8	S172	D167Y	167	Missense	distal	-5	no	9.471	9.846	PhosphoSitePlus	ICGC;COSMIC	2.638	Up-regulation
CMGC_MAPK_JNK_MAPK8_ST	O95644	NFATC1	P45983	MAPK8	S211	V210M	210	Missense	proximal	-1	no	8.735	8.743	EPSD	ICGC;COSMIC	2.638	Up-regulation
CMGC_MAPK_JNK_MAPK8_ST	O95644	NFATC1	P45983	MAPK8	S211	V210L	210	Missense	proximal	-1	no	8.735	8.740	EPSD	ICGC;COSMIC	2.638	Up-regulation
CMGC_MAPK_JNK_MAPK8_ST	O95644	NFATC1	P45983	MAPK8	S211	P208S	208	Missense	distal	-3	no	8.735	8.897	EPSD	ICGC	2.638	Up-regulation
CMGC_MAPK_JNK_MAPK8_ST	O95644	NFATC1	P45983	MAPK8	S211	P208L	208	Missense	distal	-3	no	8.735	8.556	EPSD	ICGC;COSMIC	2.638	Down-regulation
CMGC_MAPK_JNK_MAPK8_ST	O95644	NFATC1	P45983	MAPK8	S233	G232C	232	Missense	proximal	-1	no	8.750	8.755	EPSD	ICGC;COSMIC	2.638	Up-regulation
CMGC_MAPK_JNK_MAPK8_ST	O95644	NFATC1	P45983	MAPK8	S233	P234L	234	Missense	proximal	1	no	8.750	1.177	EPSD	ICGC;COSMIC	2.638	Loss
CMGC_MAPK_JNK_MAPK8_ST	O95644	NFATC1	P45983	MAPK8	S237	A244T	244	Missense	distal	7	no	9.190	9.192	EPSD	ICGC;COSMIC	2.638	Up-regulation
CMGC_MAPK_JNK_MAPK8_ST	O95644	NFATC1	P45983	MAPK8	S237	P242S	242	Missense	distal	5	no	9.190	9.107	EPSD	ICGC;COSMIC	2.638	Down-regulation
CMGC_MAPK_JNK_MAPK8_ST	O95644	NFATC1	P45983	MAPK8	S237	G232C	232	Missense	distal	-5	no	9.190	9.119	EPSD	ICGC;COSMIC	2.638	Down-regulation
CMGC_MAPK_JNK_MAPK8_ST	O95644	NFATC1	P45983	MAPK8	S237	P242L	242	Missense	distal	5	no	9.190	9.188	EPSD	ICGC;COSMIC	2.638	Down-regulation
CMGC_MAPK_JNK_MAPK8_ST	O95644	NFATC1	P45983	MAPK8	S237	P234L	234	Missense	distal	-3	no	9.190	9.011	EPSD	ICGC;COSMIC	2.638	Down-regulation
CMGC_MAPK_JNK_MAPK8_ST	O95644	NFATC1	P45983	MAPK8	S241	A244T	244	Missense	distal	3	no	9.684	9.693	EPSD	ICGC;COSMIC	2.638	Up-regulation
CMGC_MAPK_JNK_MAPK8_ST	O95644	NFATC1	P45983	MAPK8	S241	P242S	242	Missense	proximal	1	no	9.684	1.955	EPSD	ICGC;COSMIC	2.638	Loss
CMGC_MAPK_JNK_MAPK8_ST	O95644	NFATC1	P45983	MAPK8	S241	V246I	246	Missense	distal	5	no	9.684	9.650	EPSD	ICGC;COSMIC	2.638	Down-regulation
CMGC_MAPK_JNK_MAPK8_ST	O95644	NFATC1	P45983	MAPK8	S241	P242L	242	Missense	proximal	1	no	9.684	2.111	EPSD	ICGC;COSMIC	2.638	Loss
CMGC_MAPK_JNK_MAPK8_ST	O95644	NFATC1	P45983	MAPK8	S241	P234L	234	Missense	distal	-7	no	9.684	9.695	EPSD	ICGC;COSMIC	2.638	Up-regulation
CMGC_MAPK_JNK_MAPK8_ST	O95644	NFATC1	P45983	MAPK8	S261	P262L	262	Missense	proximal	1	no	9.415	1.843	EPSD	ICGC;COSMIC	2.638	Loss
CMGC_MAPK_JNK_MAPK8_ST	O95644	NFATC1	P45983	MAPK8	S278	R273L	273	Missense	distal	-5	no	11.304	11.372	EPSD	ICGC;COSMIC	2.638	Up-regulation
CMGC_MAPK_JNK_MAPK8_ST	O95644	NFATC1	P45983	MAPK8	S278	H281D	281	Missense	distal	3	no	11.304	11.260	EPSD	ICGC;COSMIC	2.638	Down-regulation
CMGC_MAPK_JNK_MAPK8_ST	O95644	NFATC1	P45983	MAPK8	S278	G272V	272	Missense	distal	-6	no	11.304	11.357	EPSD	ICGC;COSMIC	2.638	Up-regulation
CMGC_MAPK_JNK_MAPK8_ST	O95644	NFATC1	P45983	MAPK8	S278	P275S	275	Missense	distal	-3	no	11.304	11.466	EPSD	ICGC	2.638	Up-regulation
CMGC_MAPK_JNK_MAPK8_ST	O95644	NFATC1	P45983	MAPK8	S278	P276A	276	Missense	proximal	-2	no	11.304	11.254	EPSD	ICGC;COSMIC	2.638	Down-regulation
CMGC_MAPK_JNK_MAPK8_ST	O95644	NFATC1	P45983	MAPK8	S278	R273Q	273	Missense	distal	-5	no	11.304	10.989	EPSD	ICGC	2.638	Down-regulation
CMGC_MAPK_JNK_MAPK8_ST	O95644	NFATC1	P45983	MAPK8	S278	H280Y	280	Missense	proximal	2	no	11.304	11.111	EPSD	ICGC;COSMIC	2.638	Down-regulation
CMGC_MAPK_JNK_MAPK8_ST	O95644	NFATC1	P45983	MAPK8	S282	H281D	281	Missense	proximal	-1	no	9.467	9.474	EPSD	ICGC;COSMIC	2.638	Up-regulation
CMGC_MAPK_JNK_MAPK8_ST	O95644	NFATC1	P45983	MAPK8	S282	P275S	275	Missense	distal	-7	no	9.467	9.461	EPSD	ICGC	2.638	Down-regulation
CMGC_MAPK_JNK_MAPK8_ST	O95644	NFATC1	P45983	MAPK8	S282	P276A	276	Missense	distal	-6	no	9.467	9.382	EPSD	ICGC;COSMIC	2.638	Down-regulation
CMGC_MAPK_JNK_MAPK8_ST	O95644	NFATC1	P45983	MAPK8	S282	S286P	286	Missense	distal	4	no	9.467	9.442	EPSD	ICGC;COSMIC	2.638	Down-regulation
CMGC_MAPK_JNK_MAPK8_ST	O95644	NFATC1	P45983	MAPK8	S282	H280Y	280	Missense	proximal	-2	no	9.467	9.417	EPSD	ICGC;COSMIC	2.638	Down-regulation
CMGC_MAPK_JNK_MAPK8_ST	O95644	NFATC1	P45983	MAPK8	S282	G289S	289	Missense	distal	7	no	9.467	9.403	EPSD	ICGC;COSMIC	2.638	Down-regulation
CMGC_MAPK_JNK_MAPK8_ST	O95644	NFATC1	P45983	MAPK8	T284	H281D	281	Missense	distal	-3	no	7.545	7.626	EPSD	ICGC;COSMIC	2.638	Up-regulation
CMGC_MAPK_JNK_MAPK8_ST	O95644	NFATC1	P45983	MAPK8	T284	S286P	286	Missense	proximal	2	no	7.545	7.360	EPSD	ICGC;COSMIC	2.638	Down-regulation
CMGC_MAPK_JNK_MAPK8_ST	O95644	NFATC1	P45983	MAPK8	T284	S290F	290	Missense	distal	6	no	7.545	7.477	EPSD	ICGC;COSMIC	2.638	Down-regulation
CMGC_MAPK_JNK_MAPK8_ST	O95644	NFATC1	P45983	MAPK8	T284	H280Y	280	Missense	distal	-4	no	7.545	7.055	EPSD	ICGC;COSMIC	2.638	Down-regulation
CMGC_MAPK_JNK_MAPK8_ST	O95644	NFATC1	P45983	MAPK8	T284	P291T	291	Missense	distal	7	no	7.545	7.514	EPSD	ICGC;COSMIC	2.638	Down-regulation
CMGC_MAPK_JNK_MAPK8_ST	O95644	NFATC1	P45983	MAPK8	T284	G289S	289	Missense	distal	5	no	7.545	7.477	EPSD	ICGC;COSMIC	2.638	Down-regulation
CMGC_MAPK_JNK_MAPK8_ST	O95644	NFATC1	P45983	MAPK8	S286	H281D	281	Missense	distal	-5	no	9.189	9.105	EPSD	ICGC;COSMIC	2.638	Down-regulation
CMGC_MAPK_JNK_MAPK8_ST	O95644	NFATC1	P45983	MAPK8	S286	S286P	286	Missense	central	0	yes	9.189	0.000	EPSD	ICGC;COSMIC	2.638	Loss
CMGC_MAPK_JNK_MAPK8_ST	O95644	NFATC1	P45983	MAPK8	S286	S290F	290	Missense	distal	4	no	9.189	8.731	EPSD	ICGC;COSMIC	2.638	Down-regulation
CMGC_MAPK_JNK_MAPK8_ST	O95644	NFATC1	P45983	MAPK8	S286	H280Y	280	Missense	distal	-6	no	9.189	9.288	EPSD	ICGC;COSMIC	2.638	Up-regulation
CMGC_MAPK_JNK_MAPK8_ST	O95644	NFATC1	P45983	MAPK8	S286	P291T	291	Missense	distal	5	no	9.189	9.113	EPSD	ICGC;COSMIC	2.638	Down-regulation
CMGC_MAPK_JNK_MAPK8_ST	O95644	NFATC1	P45983	MAPK8	S286	G289S	289	Missense	distal	3	no	9.189	8.999	EPSD	ICGC;COSMIC	2.638	Down-regulation
CMGC_MAPK_JNK_MAPK8_ST	O95644	NFATC1	P45983	MAPK8	S290	V295M	295	Missense	distal	5	no	8.101	8.092	EPSD	ICGC	2.638	Down-regulation
CMGC_MAPK_JNK_MAPK8_ST	O95644	NFATC1	P45983	MAPK8	S290	D297Y	297	Missense	distal	7	no	8.101	8.154	EPSD	ICGC;COSMIC	2.638	Up-regulation
CMGC_MAPK_JNK_MAPK8_ST	O95644	NFATC1	P45983	MAPK8	S290	S286P	286	Missense	distal	-4	no	8.101	7.436	EPSD	ICGC;COSMIC	2.638	Down-regulation
CMGC_MAPK_JNK_MAPK8_ST	O95644	NFATC1	P45983	MAPK8	S290	T296I	296	Missense	distal	6	no	8.101	8.070	EPSD	ICGC	2.638	Down-regulation
CMGC_MAPK_JNK_MAPK8_ST	O95644	NFATC1	P45983	MAPK8	S290	S290F	290	Missense	central	0	yes	8.101	0.000	EPSD	ICGC;COSMIC	2.638	Loss
CMGC_MAPK_JNK_MAPK8_ST	O95644	NFATC1	P45983	MAPK8	S290	P291T	291	Missense	proximal	1	no	8.101	1.114	EPSD	ICGC;COSMIC	2.638	Loss
CMGC_MAPK_JNK_MAPK8_ST	O95644	NFATC1	P45983	MAPK8	S290	G289S	289	Missense	proximal	-1	no	8.101	8.125	EPSD	ICGC;COSMIC	2.638	Up-regulation
CMGC_MAPK_JNK_MAPK8_ST	O95644	NFATC1	P45983	MAPK8	S359	P362L	362	Missense	distal	3	no	8.671	8.773	EPSD	ICGC;COSMIC	2.638	Up-regulation
CMGC_MAPK_JNK_MAPK8_ST	O95644	NFATC1	P45983	MAPK8	S359	G354E	354	Missense	distal	-5	no	8.671	8.277	EPSD	ICGC;COSMIC	2.638	Down-regulation
CMGC_MAPK_JNK_MAPK8_ST	O95644	NFATC1	P45983	MAPK8	S359	P361L	361	Missense	proximal	2	no	8.671	8.595	EPSD	ICGC	2.638	Down-regulation
CMGC_MAPK_JNK_MAPK8_ST	O95644	NFATC1	P45983	MAPK8	S359	P363S	363	Missense	distal	4	no	8.671	8.697	EPSD	ICGC	2.638	Up-regulation
CMGC_MAPK_JNK_MAPK8_ST	O95644	NFATC1	P45983	MAPK8	S359	A364G	364	Missense	distal	5	no	8.671	8.731	EPSD	ICGC;COSMIC	2.638	Up-regulation
CMGC_MAPK_JNK_MAPK8_ST	O95644	NFATC1	P45983	MAPK8	S403	A397V	397	Missense	distal	-6	no	8.267	8.468	EPSD	ICGC;COSMIC	2.638	Up-regulation
CMGC_MAPK_JNK_MAPK8_ST	O95644	NFATC1	P45983	MAPK8	S403	P410T	410	Missense	distal	7	no	8.267	8.236	EPSD	ICGC;COSMIC	2.638	Down-regulation
CMGC_MAPK_JNK_MAPK8_ST	O95644	NFATC1	P45983	MAPK8	S403	P404S	404	Missense	proximal	1	no	8.267	0.538	EPSD	ICGC;COSMIC	2.638	Loss
CMGC_MAPK_JNK_MAPK8_ST	O95644	NFATC1	P45983	MAPK8	S403	S409R	409	Missense	distal	6	no	8.267	8.206	EPSD	ICGC;COSMIC	2.638	Down-regulation
CMGC_MAPK_JNK_MAPK8_ST	O95644	NFATC1	P45983	MAPK8	S409	P410T	410	Missense	proximal	1	no	11.202	4.215	EPSD	ICGC;COSMIC	2.638	Down-regulation
CMGC_MAPK_JNK_MAPK8_ST	O95644	NFATC1	P45983	MAPK8	S409	P404S	404	Missense	distal	-5	no	11.202	11.090	EPSD	ICGC;COSMIC	2.638	Down-regulation
CMGC_MAPK_JNK_MAPK8_ST	O95644	NFATC1	P45983	MAPK8	S409	P413S	413	Missense	distal	4	no	11.202	11.227	EPSD	ICGC;COSMIC	2.638	Up-regulation
CMGC_MAPK_JNK_MAPK8_ST	O95644	NFATC1	P45983	MAPK8	S409	S409R	409	Missense	central	0	yes	11.202	0.000	EPSD	ICGC;COSMIC	2.638	Loss
CMGC_MAPK_JNK_MAPK8_ST	O95644	NFATC1	P45983	MAPK8	S542	G535A	535	Missense	distal	-7	no	3.642	3.629	EPSD	ICGC;COSMIC	2.638	Down-regulation
CMGC_MAPK_JNK_MAPK8_ST	O95644	NFATC1	P45983	MAPK8	S542	R547W	547	Missense	distal	5	no	3.642	3.664	EPSD	ICGC;COSMIC	2.638	Up-regulation
CMGC_MAPK_JNK_MAPK8_ST	O95644	NFATC1	P45983	MAPK8	S542	N541K	541	Missense	proximal	-1	no	3.642	3.677	EPSD	ICGC	2.638	Up-regulation
CMGC_MAPK_JNK_MAPK8_ST	O95644	NFATC1	P45983	MAPK8	S670	R667S	667	Missense	distal	-3	no	8.923	9.228	EPSD	ICGC;COSMIC	2.638	Up-regulation
CMGC_MAPK_JNK_MAPK8_ST	O95644	NFATC1	P45983	MAPK8	S670	V674I	674	Missense	distal	4	no	8.923	9.253	EPSD	ICGC;COSMIC	2.638	Up-regulation
CMGC_MAPK_JNK_MAPK8_ST	O95644	NFATC1	P45983	MAPK8	S670	V672F	672	Missense	proximal	2	no	8.923	8.945	EPSD	ICGC;COSMIC	2.638	Up-regulation
CMGC_MAPK_JNK_MAPK8_ST	O95644	NFATC1	P45983	MAPK8	S670	V674F	674	Missense	distal	4	no	8.923	8.984	EPSD	ICGC;COSMIC	2.638	Up-regulation
CMGC_MAPK_JNK_MAPK8_ST	O95644	NFATC1	P45983	MAPK8	S670	S670N	670	Missense	central	0	yes	8.923	0.000	EPSD	ICGC;COSMIC	2.638	Loss
CMGC_MAPK_JNK_MAPK8_ST	O95644	NFATC1	P45983	MAPK8	S887	A890D	890	Missense	distal	3	no	6.037	6.139	EPSD	ICGC;COSMIC	2.638	Up-regulation
CMGC_MAPK_JNK_MAPK8_ST	O95644	NFATC1	P45983	MAPK8	S887	R893Q	893	Missense	distal	6	no	6.037	6.083	EPSD	ICGC	2.638	Up-regulation
CMGC_MAPK_JNK_MAPK8_ST	O95644	NFATC1	P45983	MAPK8	S887	R883C	883	Missense	distal	-4	no	6.037	6.071	EPSD	ICGC	2.638	Up-regulation
CMGC_MAPK_JNK_MAPK8_ST	O95644	NFATC1	P45983	MAPK8	S903	P910L	910	Missense	distal	7	no	8.141	8.181	EPSD	ICGC;COSMIC	2.638	Up-regulation
CMGC_MAPK_JNK_MAPK8_ST	Q93045	STMN2	P45983	MAPK8	S62	R69L	69	Missense	distal	7	no	8.093	8.108	EPSD	ICGC;COSMIC	2.638	Up-regulation
CMGC_MAPK_JNK_MAPK8_ST	Q93045	STMN2	P45983	MAPK8	S62	E55K	55	Missense	distal	-7	no	8.093	8.090	EPSD	ICGC	2.638	Down-regulation
CMGC_MAPK_JNK_MAPK8_ST	Q93045	STMN2	P45983	MAPK8	S62	R69Q	69	Missense	distal	7	no	8.093	8.047	EPSD	ICGC;COSMIC;CCLE	2.638	Down-regulation
CMGC_MAPK_JNK_MAPK8_ST	Q93045	STMN2	P45983	MAPK8	S62	P68Q	68	Missense	distal	6	no	8.093	8.103	EPSD	ICGC;COSMIC	2.638	Up-regulation
CMGC_MAPK_JNK_MAPK8_ST	Q93045	STMN2	P45983	MAPK8	S73	R69L	69	Missense	distal	-4	no	7.616	7.426	PhosphoSitePlus	ICGC;COSMIC	2.638	Down-regulation
CMGC_MAPK_JNK_MAPK8_ST	Q93045	STMN2	P45983	MAPK8	S73	S73F	73	Missense	central	0	yes	7.616	0.000	PhosphoSitePlus	ICGC	2.638	Loss
CMGC_MAPK_JNK_MAPK8_ST	Q93045	STMN2	P45983	MAPK8	S73	R69Q	69	Missense	distal	-4	no	7.616	8.137	PhosphoSitePlus	ICGC;COSMIC;CCLE	2.638	Up-regulation
CMGC_MAPK_JNK_MAPK8_ST	Q93045	STMN2	P45983	MAPK8	S73	P68Q	68	Missense	distal	-5	no	7.616	7.593	PhosphoSitePlus	ICGC;COSMIC	2.638	Down-regulation
CMGC_MAPK_JNK_MAPK8_ST	Q96P20	NLRP3	P45983	MAPK8	S198	P202L	202	Missense	distal	4	no	9.275	8.868	PhosphoSitePlus	ICGC;GDSC;CCLE	2.638	Down-regulation
CMGC_MAPK_JNK_MAPK8_ST	Q96P20	NLRP3	P45983	MAPK8	S387	Q391P	391	Missense	distal	4	no	2.719	2.826	EPSD	ICGC	2.638	Up-regulation
CMGC_MAPK_JNK_MAPK8_ST	Q96P20	NLRP3	P45983	MAPK8	S975	L976P	976	Missense	proximal	1	no	-0.242	7.330	EPSD	ICGC;COSMIC	2.638	Gain
CMGC_MAPK_JNK_MAPK8_ST	P10275	AR	P45983	MAPK8	S96	E93K	93	Missense	distal	-3	no	7.626	7.652	EPSD	ICGC	2.638	Up-regulation
CMGC_MAPK_JNK_MAPK8_ST	P10275	AR	P45983	MAPK8	S233	K237N	237	Missense	distal	4	no	2.978	2.500	EPSD	ICGC;COSMIC	2.638	Loss
CMGC_MAPK_JNK_MAPK8_ST	P10275	AR	P45983	MAPK8	S258	G260V	260	Missense	proximal	2	no	7.842	7.751	EPSD	ICGC;COSMIC	2.638	Down-regulation
CMGC_MAPK_JNK_MAPK8_ST	P10275	AR	P45983	MAPK8	T282	R280L	280	Missense	proximal	-2	no	7.473	7.464	EPSD	ICGC	2.638	Down-regulation
CMGC_MAPK_JNK_MAPK8_ST	P10275	AR	P45983	MAPK8	T282	A288D	288	Missense	distal	6	no	7.473	7.442	EPSD	ICGC;COSMIC	2.638	Down-regulation
CMGC_MAPK_JNK_MAPK8_ST	P10275	AR	P45983	MAPK8	S302	G300V	300	Missense	proximal	-2	no	3.833	3.762	EPSD	ICGC;COSMIC	2.638	Down-regulation
CMGC_MAPK_JNK_MAPK8_ST	P10275	AR	P45983	MAPK8	S302	T303S	303	Missense	proximal	1	no	3.833	3.091	EPSD	ICGC;COSMIC	2.638	Down-regulation
CMGC_MAPK_JNK_MAPK8_ST	P10275	AR	P45983	MAPK8	S302	A299V	299	Missense	distal	-3	no	3.833	3.404	EPSD	ICGC	2.638	Down-regulation
CMGC_MAPK_JNK_MAPK8_ST	P10275	AR	P45983	MAPK8	S310	T317A	317	Missense	distal	7	no	10.471	10.469	EPSD	ICGC;COSMIC	2.638	Down-regulation
CMGC_MAPK_JNK_MAPK8_ST	P10275	AR	P45983	MAPK8	S310	T303S	303	Missense	distal	-7	no	10.471	10.469	EPSD	ICGC;COSMIC	2.638	Down-regulation
CMGC_MAPK_JNK_MAPK8_ST	P10275	AR	P45983	MAPK8	S310	G314R	314	Missense	distal	4	no	10.471	10.449	EPSD	ICGC	2.638	Down-regulation
CMGC_MAPK_JNK_MAPK8_ST	P10275	AR	P45983	MAPK8	S516	Y514H	514	Missense	proximal	-2	no	7.555	7.605	EPSD	ICGC;GDSC;CCLE	2.638	Up-regulation
CMGC_MAPK_JNK_MAPK8_ST	P10275	AR	P45983	MAPK8	S516	S516I	516	Missense	central	0	yes	7.555	0.000	EPSD	ICGC	2.638	Loss
CMGC_MAPK_JNK_MAPK8_ST	P10275	AR	P45983	MAPK8	S516	V509L	509	Missense	distal	-7	no	7.555	7.554	EPSD	ICGC;COSMIC	2.638	Down-regulation
CMGC_MAPK_JNK_MAPK8_ST	P35568	IRS1	P45983	MAPK8	S307	T300P	300	Missense	distal	-7	no	4.798	4.803	EPSD	ICGC;COSMIC;GDSC	2.638	Up-regulation
CMGC_MAPK_JNK_MAPK8_ST	P35568	IRS1	P45983	MAPK8	S312	G319R	319	Missense	distal	7	no	8.564	8.562	PhosphoSitePlus	ICGC;COSMIC	2.638	Down-regulation
CMGC_MAPK_JNK_MAPK8_ST	P35568	IRS1	P45983	MAPK8	S345	S345N	345	Missense	central	0	yes	6.753	0.000	EPSD	ICGC	2.638	Loss
CMGC_MAPK_JNK_MAPK8_ST	P35568	IRS1	P45983	MAPK8	S348	H355Q	355	Missense	distal	7	no	8.627	8.591	EPSD	ICGC	2.638	Down-regulation
CMGC_MAPK_JNK_MAPK8_ST	P35568	IRS1	P45983	MAPK8	S348	S345N	345	Missense	distal	-3	no	8.627	8.274	EPSD	ICGC	2.638	Down-regulation
CMGC_MAPK_JNK_MAPK8_ST	P35568	IRS1	P45983	MAPK8	S383	P389T	389	Missense	distal	6	no	7.254	7.276	EPSD	ICGC	2.638	Up-regulation
CMGC_MAPK_JNK_MAPK8_ST	P35568	IRS1	P45983	MAPK8	S388	P389T	389	Missense	proximal	1	no	6.604	-0.382	EPSD	ICGC	2.638	Loss
CMGC_MAPK_JNK_MAPK8_ST	P35568	IRS1	P45983	MAPK8	S388	S393T	393	Missense	distal	5	no	6.604	6.611	EPSD	ICGC;COSMIC	2.638	Up-regulation
CMGC_MAPK_JNK_MAPK8_ST	P35568	IRS1	P45983	MAPK8	S413	S412P	412	Missense	proximal	-1	no	3.042	3.032	EPSD	ICGC	2.638	Down-regulation
CMGC_MAPK_JNK_MAPK8_ST	P35568	IRS1	P45983	MAPK8	S413	A414D	414	Missense	proximal	1	no	3.042	3.084	EPSD	ICGC	2.638	Up-regulation
CMGC_MAPK_JNK_MAPK8_ST	P35568	IRS1	P45983	MAPK8	S413	R411L	411	Missense	proximal	-2	no	3.042	3.033	EPSD	ICGC;COSMIC	2.638	Down-regulation
CMGC_MAPK_JNK_MAPK8_ST	P35568	IRS1	P45983	MAPK8	S413	R410W	410	Missense	distal	-3	no	3.042	2.956	EPSD	ICGC	2.638	Down-regulation
CMGC_MAPK_JNK_MAPK8_ST	P35568	IRS1	P45983	MAPK8	S419	S412P	412	Missense	distal	-7	no	7.849	7.855	EPSD	ICGC	2.638	Up-regulation
CMGC_MAPK_JNK_MAPK8_ST	P35568	IRS1	P45983	MAPK8	S419	S421R	421	Missense	proximal	2	no	7.849	7.608	EPSD	ICGC	2.638	Down-regulation
CMGC_MAPK_JNK_MAPK8_ST	P35568	IRS1	P45983	MAPK8	S419	A414D	414	Missense	distal	-5	no	7.849	8.091	EPSD	ICGC	2.638	Up-regulation
CMGC_MAPK_JNK_MAPK8_ST	P35568	IRS1	P45983	MAPK8	S421	S421R	421	Missense	central	0	yes	2.747	0.000	EPSD	ICGC	2.638	Loss
CMGC_MAPK_JNK_MAPK8_ST	P35568	IRS1	P45983	MAPK8	S421	A414D	414	Missense	distal	-7	no	2.747	2.755	EPSD	ICGC	2.638	Up-regulation
CMGC_MAPK_JNK_MAPK8_ST	P35568	IRS1	P45983	MAPK8	S434	D437Y	437	Missense	distal	3	no	6.144	6.306	EPSD	ICGC;COSMIC	2.638	Up-regulation
CMGC_MAPK_JNK_MAPK8_ST	P35568	IRS1	P45983	MAPK8	T453	R457H	457	Missense	distal	4	no	8.706	8.744	EPSD	ICGC;COSMIC	2.638	Up-regulation
CMGC_MAPK_JNK_MAPK8_ST	P35568	IRS1	P45983	MAPK8	T453	A456D	456	Missense	distal	3	no	8.706	8.808	EPSD	ICGC;COSMIC	2.638	Up-regulation
CMGC_MAPK_JNK_MAPK8_ST	P35568	IRS1	P45983	MAPK8	T495	R493C	493	Missense	proximal	-2	no	8.034	8.048	EPSD	ICGC	2.638	Up-regulation
CMGC_MAPK_JNK_MAPK8_ST	P35568	IRS1	P45983	MAPK8	S531	S531Y	531	Missense	central	0	yes	9.776	0.000	EPSD	ICGC	2.638	Loss
CMGC_MAPK_JNK_MAPK8_ST	P35568	IRS1	P45983	MAPK8	S547	P540S	540	Missense	distal	-7	no	2.753	2.747	EPSD	ICGC	2.638	Down-regulation
CMGC_MAPK_JNK_MAPK8_ST	P35568	IRS1	P45983	MAPK8	S636	P634S	634	Missense	proximal	-2	no	6.770	6.664	EPSD	ICGC;COSMIC	2.638	Down-regulation
CMGC_MAPK_JNK_MAPK8_ST	P35568	IRS1	P45983	MAPK8	S636	Y632C	632	Missense	distal	-4	no	6.770	7.236	EPSD	ICGC;COSMIC	2.638	Up-regulation
CMGC_MAPK_JNK_MAPK8_ST	P35568	IRS1	P45983	MAPK8	S666	P667H	667	Missense	proximal	1	no	8.196	0.280	EPSD	ICGC;COSMIC	2.638	Loss
CMGC_MAPK_JNK_MAPK8_ST	P35568	IRS1	P45983	MAPK8	S672	G678V	678	Missense	distal	6	no	9.197	9.175	EPSD	ICGC;COSMIC	2.638	Down-regulation
CMGC_MAPK_JNK_MAPK8_ST	P35568	IRS1	P45983	MAPK8	S672	D674A	674	Missense	proximal	2	no	9.197	9.357	EPSD	ICGC	2.638	Up-regulation
CMGC_MAPK_JNK_MAPK8_ST	P35568	IRS1	P45983	MAPK8	S672	P667H	667	Missense	distal	-5	no	9.197	9.394	EPSD	ICGC;COSMIC	2.638	Up-regulation
CMGC_MAPK_JNK_MAPK8_ST	P35568	IRS1	P45983	MAPK8	S745	G752S	752	Missense	distal	7	no	8.391	8.326	EPSD	ICGC;COSMIC	2.638	Down-regulation
CMGC_MAPK_JNK_MAPK8_ST	P35568	IRS1	P45983	MAPK8	S745	P746T	746	Missense	proximal	1	no	8.391	1.404	EPSD	ICGC	2.638	Loss
CMGC_MAPK_JNK_MAPK8_ST	P35568	IRS1	P45983	MAPK8	S745	P746S	746	Missense	proximal	1	no	8.391	0.662	EPSD	ICGC	2.638	Loss
CMGC_MAPK_JNK_MAPK8_ST	P35568	IRS1	P45983	MAPK8	S745	D748N	748	Missense	distal	3	no	8.391	8.474	EPSD	ICGC	2.638	Up-regulation
CMGC_MAPK_JNK_MAPK8_ST	P35568	IRS1	P45983	MAPK8	S918	C923F	923	Missense	distal	5	no	7.634	7.655	EPSD	ICGC;COSMIC	2.638	Up-regulation
CMGC_MAPK_JNK_MAPK8_ST	P35568	IRS1	P45983	MAPK8	S918	S917R	917	Missense	proximal	-1	no	7.634	7.608	EPSD	ICGC	2.638	Down-regulation
CMGC_MAPK_JNK_MAPK8_ST	P35568	IRS1	P45983	MAPK8	S918	P924T	924	Missense	distal	6	no	7.634	7.655	EPSD	ICGC	2.638	Up-regulation
CMGC_MAPK_JNK_MAPK8_ST	P35568	IRS1	P45983	MAPK8	S918	R922G	922	Missense	distal	4	no	7.634	7.655	EPSD	ICGC;COSMIC	2.638	Up-regulation
CMGC_MAPK_JNK_MAPK8_ST	P35568	IRS1	P45983	MAPK8	S1005	D1003N	1003	Missense	proximal	-2	no	7.156	7.058	EPSD	ICGC;COSMIC	2.638	Down-regulation
CMGC_MAPK_JNK_MAPK8_ST	P35568	IRS1	P45983	MAPK8	S1041	P1044T	1044	Missense	distal	3	no	2.655	2.558	EPSD	ICGC;COSMIC	2.638	Loss
CMGC_MAPK_JNK_MAPK8_ST	P35568	IRS1	P45983	MAPK8	S1043	P1044T	1044	Missense	proximal	1	no	8.796	1.809	EPSD	ICGC;COSMIC	2.638	Loss
CMGC_MAPK_JNK_MAPK8_ST	P35568	IRS1	P45983	MAPK8	S1078	A1071T	1071	Missense	distal	-7	no	5.863	5.865	EPSD	ICGC;GDSC;CCLE	2.638	Up-regulation
CMGC_MAPK_JNK_MAPK8_ST	P35568	IRS1	P45983	MAPK8	T1107	S1106L	1106	Missense	proximal	-1	no	7.378	7.349	EPSD	ICGC;COSMIC	2.638	Down-regulation
CMGC_MAPK_JNK_MAPK8_ST	P35568	IRS1	P45983	MAPK8	T1107	R1112W	1112	Missense	distal	5	no	7.378	7.400	EPSD	ICGC;COSMIC	2.638	Up-regulation
CMGC_MAPK_JNK_MAPK8_ST	P35568	IRS1	P45983	MAPK8	T1107	R1112G	1112	Missense	distal	5	no	7.378	7.375	EPSD	ICGC;COSMIC	2.638	Down-regulation
CMGC_MAPK_JNK_MAPK8_ST	P35568	IRS1	P45983	MAPK8	S1109	S1106L	1106	Missense	distal	-3	no	2.694	2.352	EPSD	ICGC;COSMIC	2.638	Loss
CMGC_MAPK_JNK_MAPK8_ST	P35568	IRS1	P45983	MAPK8	S1109	R1112W	1112	Missense	distal	3	no	2.694	2.744	EPSD	ICGC;COSMIC	2.638	Up-regulation
CMGC_MAPK_JNK_MAPK8_ST	P35568	IRS1	P45983	MAPK8	S1109	R1112G	1112	Missense	distal	3	no	2.694	2.701	EPSD	ICGC;COSMIC	2.638	Up-regulation
CMGC_MAPK_JNK_MAPK8_ST	P35568	IRS1	P45983	MAPK8	S1143	D1137N	1137	Missense	distal	-6	no	3.274	3.357	EPSD	ICGC	2.638	Up-regulation
CMGC_MAPK_JNK_MAPK8_ST	P35568	IRS1	P45983	MAPK8	T1196	Q1190K	1190	Missense	distal	-6	no	8.037	7.972	EPSD	ICGC	2.638	Down-regulation
CMGC_MAPK_JNK_MAPK8_ST	P35568	IRS1	P45983	MAPK8	S1218	T1219P	1219	Missense	proximal	1	no	0.267	7.254	EPSD	ICGC;COSMIC;GDSC	2.638	Gain
CMGC_MAPK_JNK_MAPK8_ST	P35568	IRS1	P45983	MAPK8	S1231	Q1235H	1235	Missense	distal	4	no	3.402	3.206	EPSD	ICGC;COSMIC	2.638	Down-regulation
CMGC_MAPK_JNK_MAPK8_ST	Q15750	TAB1	P45983	MAPK8	S16	P15Q	15	Missense	proximal	-1	no	2.729	2.734	EPSD	ICGC;COSMIC	2.638	Up-regulation
CMGC_MAPK_JNK_MAPK8_ST	Q15750	TAB1	P45983	MAPK8	S339	R333Q	333	Missense	distal	-6	no	3.196	3.095	EPSD	ICGC	2.638	Down-regulation
CMGC_MAPK_JNK_MAPK8_ST	Q15750	TAB1	P45983	MAPK8	S339	A343S	343	Missense	distal	4	no	3.196	3.197	EPSD	ICGC	2.638	Up-regulation
CMGC_MAPK_JNK_MAPK8_ST	Q15750	TAB1	P45983	MAPK8	S339	S339I	339	Missense	central	0	yes	3.196	0.000	EPSD	ICGC;COSMIC	2.638	Loss
CMGC_MAPK_JNK_MAPK8_ST	Q15750	TAB1	P45983	MAPK8	T376	S373I	373	Missense	distal	-3	no	7.461	7.302	EPSD	ICGC	2.638	Down-regulation
CMGC_MAPK_JNK_MAPK8_ST	Q15750	TAB1	P45983	MAPK8	T376	P381S	381	Missense	distal	5	no	7.461	7.378	EPSD	ICGC	2.638	Down-regulation
CMGC_MAPK_JNK_MAPK8_ST	Q15750	TAB1	P45983	MAPK8	T376	S378I	378	Missense	proximal	2	no	7.461	7.339	EPSD	ICGC	2.638	Down-regulation
CMGC_MAPK_JNK_MAPK8_ST	Q15750	TAB1	P45983	MAPK8	T376	Q374H	374	Missense	proximal	-2	no	7.461	7.387	EPSD	ICGC;COSMIC	2.638	Down-regulation
CMGC_MAPK_JNK_MAPK8_ST	Q15750	TAB1	P45983	MAPK8	T376	S378R	378	Missense	proximal	2	no	7.461	7.219	EPSD	ICGC;COSMIC	2.638	Down-regulation
CMGC_MAPK_JNK_MAPK8_ST	Q15750	TAB1	P45983	MAPK8	T376	Q374K	374	Missense	proximal	-2	no	7.461	7.496	EPSD	ICGC;COSMIC	2.638	Up-regulation
CMGC_MAPK_JNK_MAPK8_ST	Q15750	TAB1	P45983	MAPK8	S378	S373I	373	Missense	distal	-5	no	9.001	9.205	EPSD	ICGC	2.638	Up-regulation
CMGC_MAPK_JNK_MAPK8_ST	Q15750	TAB1	P45983	MAPK8	S378	P381S	381	Missense	distal	3	no	9.001	8.875	EPSD	ICGC	2.638	Down-regulation
CMGC_MAPK_JNK_MAPK8_ST	Q15750	TAB1	P45983	MAPK8	S378	S378I	378	Missense	central	0	yes	9.001	0.000	EPSD	ICGC	2.638	Loss
CMGC_MAPK_JNK_MAPK8_ST	Q15750	TAB1	P45983	MAPK8	S378	Q374H	374	Missense	distal	-4	no	9.001	8.539	EPSD	ICGC;COSMIC	2.638	Down-regulation
CMGC_MAPK_JNK_MAPK8_ST	Q15750	TAB1	P45983	MAPK8	S378	S378R	378	Missense	central	0	yes	9.001	0.000	EPSD	ICGC;COSMIC	2.638	Loss
CMGC_MAPK_JNK_MAPK8_ST	Q15750	TAB1	P45983	MAPK8	S378	Q374K	374	Missense	distal	-4	no	9.001	9.394	EPSD	ICGC;COSMIC	2.638	Up-regulation
CMGC_MAPK_JNK_MAPK8_ST	Q15750	TAB1	P45983	MAPK8	T431	L434I	434	Missense	distal	3	no	6.638	6.534	EPSD	ICGC;COSMIC	2.638	Down-regulation
CMGC_MAPK_JNK_MAPK8_ST	Q15750	TAB1	P45983	MAPK8	T431	S438R	438	Missense	distal	7	no	6.638	6.701	EPSD	ICGC;COSMIC	2.638	Up-regulation
CMGC_MAPK_JNK_MAPK8_ST	Q15750	TAB1	P45983	MAPK8	S438	L434I	434	Missense	distal	-4	no	7.509	7.860	PhosphoSitePlus	ICGC;COSMIC	2.638	Up-regulation
CMGC_MAPK_JNK_MAPK8_ST	Q15750	TAB1	P45983	MAPK8	S438	S438R	438	Missense	central	0	yes	7.509	0.000	PhosphoSitePlus	ICGC;COSMIC	2.638	Loss
CMGC_MAPK_JNK_MAPK8_ST	P40763	STAT3	P45983	MAPK8	T714	T717N	717	Missense	distal	3	no	8.025	8.200	EPSD	ICGC	2.638	Up-regulation
CMGC_MAPK_JNK_MAPK8_ST	P40763	STAT3	P45983	MAPK8	T714	P715L	715	Missense	proximal	1	no	8.025	0.452	EPSD	ICGC	2.638	Loss
CMGC_MAPK_JNK_MAPK8_ST	P40763	STAT3	P45983	MAPK8	T714	P715Q	715	Missense	proximal	1	no	8.025	0.915	EPSD	ICGC;COSMIC	2.638	Loss
CMGC_MAPK_JNK_MAPK8_ST	P40763	STAT3	P45983	MAPK8	T721	L724P	724	Missense	distal	3	no	2.709	2.607	EPSD	ICGC;COSMIC	2.638	Loss
CMGC_MAPK_JNK_MAPK8_ST	P40763	STAT3	P45983	MAPK8	T721	T717N	717	Missense	distal	-4	no	2.709	2.049	EPSD	ICGC	2.638	Loss
CMGC_MAPK_JNK_MAPK8_ST	P40763	STAT3	P45983	MAPK8	T721	S727P	727	Missense	distal	6	no	2.709	2.685	EPSD	ICGC	2.638	Down-regulation
CMGC_MAPK_JNK_MAPK8_ST	P40763	STAT3	P45983	MAPK8	T721	P715L	715	Missense	distal	-6	no	2.709	2.800	EPSD	ICGC	2.638	Up-regulation
CMGC_MAPK_JNK_MAPK8_ST	P40763	STAT3	P45983	MAPK8	T721	P715Q	715	Missense	distal	-6	no	2.709	2.673	EPSD	ICGC;COSMIC	2.638	Down-regulation
CMGC_MAPK_JNK_MAPK8_ST	P40763	STAT3	P45983	MAPK8	S727	L724P	724	Missense	distal	-3	no	7.051	7.230	PhosphoSitePlus	ICGC;COSMIC	2.638	Up-regulation
CMGC_MAPK_JNK_MAPK8_ST	P40763	STAT3	P45983	MAPK8	S727	S727P	727	Missense	central	0	yes	7.051	0.000	PhosphoSitePlus	ICGC	2.638	Loss
CMGC_MAPK_JNK_MAPK8_ST	P40763	STAT3	P45983	MAPK8	S727	L734S	734	Missense	distal	7	no	7.051	6.973	PhosphoSitePlus	ICGC;COSMIC	2.638	Down-regulation
CMGC_MAPK_JNK_MAPK8_ST	P61978	HNRNPK	P45983	MAPK8	S116	T118N	118	Missense	proximal	2	no	7.091	6.826	EPSD	ICGC	2.638	Down-regulation
CMGC_MAPK_JNK_MAPK8_ST	P61978	HNRNPK	P45983	MAPK8	S116	E110Q	110	Missense	distal	-6	no	7.091	7.151	EPSD	ICGC	2.638	Up-regulation
CMGC_MAPK_JNK_MAPK8_ST	P61978	HNRNPK	P45983	MAPK8	S116	E110D	110	Missense	distal	-6	no	7.091	7.191	EPSD	ICGC;COSMIC	2.638	Up-regulation
CMGC_MAPK_JNK_MAPK8_ST	P61978	HNRNPK	P45983	MAPK8	S116	L123H	123	Missense	distal	7	no	7.091	7.065	EPSD	ICGC;COSMIC	2.638	Down-regulation
CMGC_MAPK_JNK_MAPK8_ST	P61978	HNRNPK	P45983	MAPK8	T177	N173K	173	Missense	distal	-4	no	2.175	3.161	EPSD	ICGC;COSMIC	2.638	Gain
CMGC_MAPK_JNK_MAPK8_ST	P61978	HNRNPK	P45983	MAPK8	S216	D211H	211	Missense	distal	-5	no	7.728	7.812	EPSD;PhosphoSitePlus	ICGC;COSMIC	2.638	Up-regulation
CMGC_MAPK_JNK_MAPK8_ST	P61978	HNRNPK	P45983	MAPK8	S216	I213M	213	Missense	distal	-3	no	7.728	7.562	EPSD;PhosphoSitePlus	ICGC	2.638	Down-regulation
CMGC_MAPK_JNK_MAPK8_ST	P61978	HNRNPK	P45983	MAPK8	S420	I423V	423	Missense	distal	3	no	3.142	3.264	EPSD	ICGC;COSMIC	2.638	Up-regulation
CMGC_MAPK_JNK_MAPK8_ST	P63104	YWHAZ	P45983	MAPK8	S58	A54P	54	Missense	distal	-4	no	3.016	2.528	EPSD	ICGC;COSMIC	2.638	Loss
CMGC_MAPK_JNK_MAPK8_ST	P63104	YWHAZ	P45983	MAPK8	S184	Y179H	179	Missense	distal	-5	no	9.105	8.813	PhosphoSitePlus	ICGC;COSMIC	2.638	Down-regulation
CMGC_MAPK_JNK_MAPK8_ST	P98177	FOXO4	P45983	MAPK8	S241	P242L	242	Missense	proximal	1	no	8.461	0.889	EPSD	ICGC;COSMIC	2.638	Loss
CMGC_MAPK_JNK_MAPK8_ST	P31946	YWHAB	P45983	MAPK8	S60	R57C	57	Missense	distal	-3	no	3.202	3.251	EPSD	ICGC;COSMIC	2.638	Up-regulation
CMGC_MAPK_JNK_MAPK8_ST	P31946	YWHAB	P45983	MAPK8	S60	A56T	56	Missense	distal	-4	no	3.202	3.165	EPSD	ICGC;COSMIC;GDSC	2.638	Down-regulation
CMGC_MAPK_JNK_MAPK8_ST	P31946	YWHAB	P45983	MAPK8	S186	S192I	192	Missense	distal	6	no	9.350	9.317	PhosphoSitePlus	ICGC;COSMIC	2.638	Down-regulation
CMGC_MAPK_JNK_MAPK8_ST	Q14653	IRF3	P45983	MAPK8	T3	L9M	9	Missense	distal	6	no	7.540	7.548	EPSD	ICGC;COSMIC	2.638	Up-regulation
CMGC_MAPK_JNK_MAPK8_ST	Q14653	IRF3	P45983	MAPK8	S123	Q119K	119	Missense	distal	-4	no	7.954	8.347	EPSD	ICGC	2.638	Up-regulation
CMGC_MAPK_JNK_MAPK8_ST	P04150	NR3C1	P45983	MAPK8	T8	E13Q	13	Missense	distal	5	no	8.138	8.169	EPSD	ICGC;COSMIC	2.638	Up-regulation
CMGC_MAPK_JNK_MAPK8_ST	P04150	NR3C1	P45983	MAPK8	T8	S3F	3	Missense	distal	-5	no	8.138	8.606	EPSD	ICGC	2.638	Up-regulation
CMGC_MAPK_JNK_MAPK8_ST	P04150	NR3C1	P45983	MAPK8	S45	A49D	49	Missense	distal	4	no	8.217	8.016	EPSD	ICGC	2.638	Down-regulation
CMGC_MAPK_JNK_MAPK8_ST	P04150	NR3C1	P45983	MAPK8	S226	E221K	221	Missense	distal	-5	no	7.390	7.313	PhosphoSitePlus	ICGC;COSMIC	2.638	Down-regulation
CMGC_MAPK_JNK_MAPK8_ST	P04150	NR3C1	P45983	MAPK8	S226	E231K	231	Missense	distal	5	no	7.390	7.381	PhosphoSitePlus	ICGC;COSMIC	2.638	Down-regulation
CMGC_MAPK_JNK_MAPK8_ST	P04150	NR3C1	P45983	MAPK8	S267	S269G	269	Missense	proximal	2	no	7.238	7.036	EPSD	ICGC	2.638	Down-regulation
CMGC_MAPK_JNK_MAPK8_ST	P04150	NR3C1	P45983	MAPK8	S267	S269N	269	Missense	proximal	2	no	7.238	6.976	EPSD	ICGC;COSMIC	2.638	Down-regulation
CMGC_MAPK_JNK_MAPK8_ST	P04150	NR3C1	P45983	MAPK8	S404	T411S	411	Missense	distal	7	no	8.117	8.109	EPSD	ICGC;COSMIC	2.638	Down-regulation
CMGC_MAPK_JNK_MAPK8_ST	Q9NPI6	DCP1A	P45983	MAPK8	S142	D139N	139	Missense	distal	-3	no	7.254	7.088	EPSD	ICGC	2.638	Down-regulation
CMGC_MAPK_JNK_MAPK8_ST	Q9NPI6	DCP1A	P45983	MAPK8	S142	G148C	148	Missense	distal	6	no	7.254	7.262	EPSD	ICGC;COSMIC	2.638	Up-regulation
CMGC_MAPK_JNK_MAPK8_ST	Q9NPI6	DCP1A	P45983	MAPK8	S180	S186G	186	Missense	distal	6	no	7.648	7.591	EPSD	ICGC;COSMIC	2.638	Down-regulation
CMGC_MAPK_JNK_MAPK8_ST	Q9NPI6	DCP1A	P45983	MAPK8	T289	T290I	290	Missense	proximal	1	no	2.163	3.276	EPSD	ICGC;COSMIC	2.638	Gain
CMGC_MAPK_JNK_MAPK8_ST	Q9NPI6	DCP1A	P45983	MAPK8	T290	T290I	290	Missense	central	0	yes	7.257	0.000	EPSD	ICGC;COSMIC	2.638	Loss
CMGC_MAPK_JNK_MAPK8_ST	Q9NPI6	DCP1A	P45983	MAPK8	T295	T290I	290	Missense	distal	-5	no	5.896	6.101	EPSD	ICGC;COSMIC	2.638	Up-regulation
CMGC_MAPK_JNK_MAPK8_ST	Q9NPI6	DCP1A	P45983	MAPK8	S315	T321N	321	Missense	distal	6	no	8.015	7.953	PhosphoSitePlus	ICGC	2.638	Down-regulation
CMGC_MAPK_JNK_MAPK8_ST	Q9NPI6	DCP1A	P45983	MAPK8	S319	T321N	321	Missense	proximal	2	no	7.701	7.436	EPSD	ICGC	2.638	Down-regulation
CMGC_MAPK_JNK_MAPK8_ST	Q9NPI6	DCP1A	P45983	MAPK8	T348	T348K	348	Missense	central	0	yes	7.103	0.000	EPSD	ICGC	2.638	Loss
CMGC_MAPK_JNK_MAPK8_ST	Q9NPI6	DCP1A	P45983	MAPK8	S353	T348K	348	Missense	distal	-5	no	7.247	7.153	EPSD	ICGC	2.638	Down-regulation
CMGC_MAPK_JNK_MAPK8_ST	Q9NPI6	DCP1A	P45983	MAPK8	S373	S367R	367	Missense	distal	-6	no	7.578	7.733	EPSD	ICGC;COSMIC	2.638	Up-regulation
CMGC_MAPK_JNK_MAPK8_ST	Q9NPI6	DCP1A	P45983	MAPK8	T401	Q408K	408	Missense	distal	7	no	8.746	8.714	EPSD	ICGC	2.638	Down-regulation
CMGC_MAPK_JNK_MAPK8_ST	Q9NPI6	DCP1A	P45983	MAPK8	S422	L428I	428	Missense	distal	6	no	8.028	8.066	EPSD	ICGC	2.638	Up-regulation
CMGC_MAPK_JNK_MAPK8_ST	Q9NPI6	DCP1A	P45983	MAPK8	T430	L428I	428	Missense	proximal	-2	no	6.351	6.440	EPSD	ICGC	2.638	Up-regulation
CMGC_MAPK_JNK_MAPK8_ST	Q9NPI6	DCP1A	P45983	MAPK8	S523	E518Q	518	Missense	distal	-5	no	7.835	7.942	EPSD	ICGC;COSMIC	2.638	Up-regulation
CMGC_MAPK_JNK_MAPK8_ST	Q9NPI6	DCP1A	P45983	MAPK8	S525	E518Q	518	Missense	distal	-7	no	6.620	6.624	EPSD	ICGC;COSMIC	2.638	Up-regulation
CMGC_MAPK_JNK_MAPK8_ST	Q16621	NFE2	P45983	MAPK8	S2	P6H	6	Missense	distal	4	no	7.248	6.945	EPSD	ICGC	2.638	Down-regulation
CMGC_MAPK_JNK_MAPK8_ST	Q16621	NFE2	P45983	MAPK8	S2	P3T	3	Missense	proximal	1	no	7.248	0.261	EPSD	ICGC;COSMIC	2.638	Loss
CMGC_MAPK_JNK_MAPK8_ST	Q16621	NFE2	P45983	MAPK8	S107	S113L	113	Missense	distal	6	no	2.972	2.901	EPSD	ICGC;COSMIC	2.638	Down-regulation
CMGC_MAPK_JNK_MAPK8_ST	Q16621	NFE2	P45983	MAPK8	S107	S111G	111	Missense	distal	4	no	2.972	2.628	EPSD	ICGC;COSMIC	2.638	Loss
CMGC_MAPK_JNK_MAPK8_ST	Q16621	NFE2	P45983	MAPK8	S107	P109T	109	Missense	proximal	2	no	2.972	3.160	EPSD	ICGC	2.638	Up-regulation
CMGC_MAPK_JNK_MAPK8_ST	Q16621	NFE2	P45983	MAPK8	S157	S153R	153	Missense	distal	-4	no	4.371	3.570	PhosphoSitePlus	ICGC	2.638	Down-regulation
CMGC_MAPK_JNK_MAPK8_ST	Q16621	NFE2	P45983	MAPK8	S157	L150V	150	Missense	distal	-7	no	4.371	4.373	PhosphoSitePlus	ICGC;COSMIC	2.638	Up-regulation
CMGC_MAPK_JNK_MAPK8_ST	Q16621	NFE2	P45983	MAPK8	S346	S344N	344	Missense	proximal	-2	no	8.549	8.431	EPSD	ICGC;COSMIC	2.638	Down-regulation
CMGC_MAPK_JNK_MAPK8_ST	Q16621	NFE2	P45983	MAPK8	S346	P347S	347	Missense	proximal	1	no	8.549	0.820	EPSD	ICGC	2.638	Loss
CAMK_CAMKL_MARK_MARK3_ST	Q06413	MEF2C	P27448	MARK3	S59	T60N	60	Missense	proximal	1	no	272.923	272.909	EPSD	ICGC	255.132	Down-regulation
CAMK_CAMKL_MARK_MARK3_ST	Q06413	MEF2C	P27448	MARK3	S59	L66I	66	Missense	distal	7	no	272.923	273.751	EPSD	ICGC;COSMIC	255.132	Up-regulation
CAMK_CAMKL_MARK_MARK3_ST	Q06413	MEF2C	P27448	MARK3	S59	D63E	63	Missense	distal	4	no	272.923	272.352	EPSD	ICGC;COSMIC	255.132	Down-regulation
CAMK_CAMKL_MARK_MARK3_ST	Q06413	MEF2C	P27448	MARK3	S98	D105N	105	Missense	distal	7	no	283.062	282.084	EPSD	ICGC;COSMIC	255.132	Down-regulation
CAMK_CAMKL_MARK_MARK3_ST	Q06413	MEF2C	P27448	MARK3	S98	D104E	104	Missense	distal	6	no	283.062	293.602	EPSD	ICGC;COSMIC	255.132	Up-regulation
CAMK_CAMKL_MARK_MARK3_ST	Q06413	MEF2C	P27448	MARK3	S192	H188R	188	Missense	distal	-4	no	314.836	335.368	EPSD	ICGC;COSMIC	255.132	Up-regulation
CAMK_CAMKL_MARK_MARK3_ST	Q06413	MEF2C	P27448	MARK3	S192	P190L	190	Missense	proximal	-2	no	314.836	315.673	EPSD	ICGC;COSMIC	255.132	Up-regulation
CAMK_CAMKL_MARK_MARK3_ST	Q06413	MEF2C	P27448	MARK3	S192	R189Q	189	Missense	distal	-3	no	314.836	286.887	EPSD	ICGC;COSMIC	255.132	Down-regulation
CAMK_CAMKL_MARK_MARK3_ST	Q06413	MEF2C	P27448	MARK3	S192	P190S	190	Missense	proximal	-2	no	314.836	308.485	EPSD	ICGC;COSMIC	255.132	Down-regulation
CAMK_CAMKL_MARK_MARK3_ST	Q06413	MEF2C	P27448	MARK3	S192	T196K	196	Missense	distal	4	no	314.836	313.816	EPSD	ICGC	255.132	Down-regulation
CAMK_CAMKL_MARK_MARK3_ST	Q06413	MEF2C	P27448	MARK3	S192	S192R	192	Missense	central	0	yes	314.836	0.000	EPSD	ICGC	255.132	Loss
CAMK_CAMKL_MARK_MARK3_ST	Q06413	MEF2C	P27448	MARK3	S192	G194C	194	Missense	proximal	2	no	314.836	282.898	EPSD	ICGC;COSMIC	255.132	Down-regulation
CAMK_CAMKL_MARK_MARK3_ST	Q06413	MEF2C	P27448	MARK3	S222	R220Q	220	Missense	proximal	-2	no	529.076	527.641	PhosphoSitePlus	ICGC;COSMIC	255.132	Down-regulation
CAMK_CAMKL_MARK_MARK3_ST	Q06413	MEF2C	P27448	MARK3	S222	G215W	215	Missense	distal	-7	no	529.076	532.111	PhosphoSitePlus	ICGC;COSMIC	255.132	Up-regulation
CAMK_CAMKL_MARK_MARK3_ST	Q06413	MEF2C	P27448	MARK3	S222	P219S	219	Missense	distal	-3	no	529.076	536.221	PhosphoSitePlus	ICGC;COSMIC	255.132	Up-regulation
CAMK_CAMKL_MARK_MARK3_ST	Q06413	MEF2C	P27448	MARK3	S222	V227A	227	Missense	distal	5	no	529.076	547.387	PhosphoSitePlus	ICGC;COSMIC	255.132	Up-regulation
CAMK_CAMKL_MARK_MARK3_ST	Q06413	MEF2C	P27448	MARK3	S387	L380F	380	Missense	distal	-7	no	325.011	323.853	EPSD	ICGC;COSMIC	255.132	Down-regulation
CAMK_CAMKL_MARK_MARK3_ST	Q06413	MEF2C	P27448	MARK3	S392	P397R	397	Missense	distal	5	no	245.990	271.470	EPSD	ICGC;COSMIC	255.132	Gain
CAMK_CAMKL_MARK_MARK3_ST	Q06413	MEF2C	P27448	MARK3	S392	P397T	397	Missense	distal	5	no	245.990	272.299	EPSD	ICGC;COSMIC	255.132	Gain
CAMK_CAMKL_MARK_MARK3_ST	Q06413	MEF2C	P27448	MARK3	S396	P397R	397	Missense	proximal	1	no	314.015	314.006	EPSD	ICGC;COSMIC	255.132	Down-regulation
CAMK_CAMKL_MARK_MARK3_ST	Q99689	FEZ1	P27448	MARK3	T344	L342V	342	Missense	proximal	-2	no	257.141	250.457	EPSD	ICGC;COSMIC	255.132	Loss
CAMK_CAMKL_MARK_MARK3_ST	Q99689	FEZ1	P27448	MARK3	T344	P347T	347	Missense	distal	3	no	257.141	257.133	EPSD	ICGC	255.132	Down-regulation
CAMK_CAMKL_MARK_MARK3_ST	Q92974	ARHGEF2	P27448	MARK3	S109	N102K	102	Missense	distal	-7	no	292.759	297.352	EPSD	ICGC	255.132	Up-regulation
CAMK_CAMKL_MARK_MARK3_ST	Q92974	ARHGEF2	P27448	MARK3	S142	R139S	139	Missense	distal	-3	no	286.251	266.500	EPSD	ICGC	255.132	Down-regulation
CAMK_CAMKL_MARK_MARK3_ST	Q92974	ARHGEF2	P27448	MARK3	S143	R139S	139	Missense	distal	-4	no	373.920	368.555	EPSD	ICGC	255.132	Down-regulation
CAMK_CAMKL_MARK_MARK3_ST	Q92974	ARHGEF2	P27448	MARK3	S172	R169L	169	Missense	distal	-3	no	335.738	292.336	EPSD	ICGC;COSMIC	255.132	Down-regulation
CAMK_CAMKL_MARK_MARK3_ST	Q92974	ARHGEF2	P27448	MARK3	S174	R169L	169	Missense	distal	-5	no	214.646	281.678	EPSD	ICGC;COSMIC	255.132	Gain
CAMK_CAMKL_MARK_MARK3_ST	Q92974	ARHGEF2	P27448	MARK3	S940	E935K	935	Missense	distal	-5	no	154.628	267.917	EPSD	ICGC	255.132	Gain
CAMK_CAMKL_MARK_MARK3_ST	P41236	PPP1R2	P27448	MARK3	T19	L15F	15	Missense	distal	-4	no	291.085	285.110	EPSD	ICGC;COSMIC	255.132	Down-regulation
CAMK_CAMKL_MARK_MARK3_ST	P41236	PPP1R2	P27448	MARK3	S20	L15F	15	Missense	distal	-5	no	482.335	385.435	EPSD	ICGC;COSMIC	255.132	Down-regulation
CAMK_CAMKL_MARK_MARK3_ST	P41236	PPP1R2	P27448	MARK3	T21	L15F	15	Missense	distal	-6	no	299.850	300.644	EPSD	ICGC;COSMIC	255.132	Up-regulation
CAMK_CAMKL_MARK_MARK3_ST	P41236	PPP1R2	P27448	MARK3	S24	Q31K	31	Missense	distal	7	no	311.243	307.218	EPSD	ICGC	255.132	Down-regulation
CAMK_CAMKL_MARK_MARK3_ST	P41236	PPP1R2	P27448	MARK3	S28	Q31K	31	Missense	distal	3	no	264.959	264.023	EPSD	ICGC	255.132	Down-regulation
CAMK_CAMKL_MARK_MARK3_ST	P41236	PPP1R2	P27448	MARK3	S72	D69G	69	Missense	distal	-3	no	555.959	529.359	PhosphoSitePlus	ICGC	255.132	Down-regulation
CAMK_CAMKL_MARK_MARK3_ST	P41236	PPP1R2	P27448	MARK3	T73	D69G	69	Missense	distal	-4	no	309.398	293.159	EPSD	ICGC	255.132	Down-regulation
CAMK_CAMKL_MARK_MARK3_ST	P41236	PPP1R2	P27448	MARK3	T177	E172K	172	Missense	distal	-5	no	148.336	261.624	EPSD	ICGC;COSMIC	255.132	Gain
CAMK_CAMKL_MARK_MARK3_ST	P30307	CDC25C	P27448	MARK3	S38	L33P	33	Missense	distal	-5	no	382.967	275.065	EPSD	ICGC;COSMIC	255.132	Down-regulation
CAMK_CAMKL_MARK_MARK3_ST	P30307	CDC25C	P27448	MARK3	S57	G55S	55	Missense	proximal	-2	no	268.784	274.325	EPSD	ICGC;COSMIC	255.132	Up-regulation
CAMK_CAMKL_MARK_MARK3_ST	P30307	CDC25C	P27448	MARK3	S57	A58E	58	Missense	proximal	1	no	268.784	268.772	EPSD	ICGC	255.132	Down-regulation
CAMK_CAMKL_MARK_MARK3_ST	P30307	CDC25C	P27448	MARK3	S168	T172A	172	Missense	distal	4	no	305.962	305.727	EPSD	ICGC;COSMIC	255.132	Down-regulation
CAMK_CAMKL_MARK_MARK3_ST	P30307	CDC25C	P27448	MARK3	T171	T172A	172	Missense	proximal	1	no	360.911	360.915	EPSD	ICGC;COSMIC	255.132	Up-regulation
CAMK_CAMKL_MARK_MARK3_ST	P30307	CDC25C	P27448	MARK3	S207	Q202K	202	Missense	distal	-5	no	242.365	381.364	EPSD	ICGC	255.132	Gain
CAMK_CAMKL_MARK_MARK3_ST	P30307	CDC25C	P27448	MARK3	S214	E219D	219	Missense	distal	5	no	289.286	274.245	EPSD	ICGC;COSMIC	255.132	Down-regulation
CAMK_CAMKL_MARK_MARK3_ST	P30307	CDC25C	P27448	MARK3	S216	E219D	219	Missense	distal	3	no	655.162	655.132	PhosphoSitePlus	ICGC;COSMIC	255.132	Down-regulation
CAMK_CAMKL_MARK_MARK3_ST	P30307	CDC25C	P27448	MARK3	T236	D239N	239	Missense	distal	3	no	353.961	353.774	EPSD	ICGC	255.132	Down-regulation
CAMK_CAMKL_MARK_MARK3_ST	P30307	CDC25C	P27448	MARK3	T236	N235S	235	Missense	proximal	-1	no	353.961	354.973	EPSD	ICGC	255.132	Up-regulation
CAMK_CAMKL_MARK_MARK3_ST	P30307	CDC25C	P27448	MARK3	S277	G280W	280	Missense	distal	3	no	307.253	306.786	EPSD	ICGC;COSMIC	255.132	Down-regulation
AGC_Akt_AKT2_ST	Q04656	ATP7A	P31751	AKT2	S262	K256R	256	Missense	distal	-6	no	26.611	26.356	EPSD	ICGC	19.022	Down-regulation
AGC_Akt_AKT2_ST	Q04656	ATP7A	P31751	AKT2	S262	S262F	262	Missense	central	0	yes	26.611	0.000	EPSD	ICGC	19.022	Loss
AGC_Akt_AKT2_ST	Q04656	ATP7A	P31751	AKT2	S360	P367S	367	Missense	distal	7	no	21.226	21.550	EPSD	ICGC	19.022	Up-regulation
AGC_Akt_AKT2_ST	Q04656	ATP7A	P31751	AKT2	S639	V632F	632	Missense	distal	-7	no	24.731	25.298	EPSD	ICGC	19.022	Up-regulation
AGC_Akt_AKT2_ST	Q13835	PKP1	P31751	AKT2	S21	C14F	14	Missense	distal	-7	no	20.662	20.644	EPSD	ICGC;COSMIC	19.022	Down-regulation
AGC_Akt_AKT2_ST	Q13835	PKP1	P31751	AKT2	S142	C135F	135	Missense	distal	-7	no	24.069	24.052	EPSD	ICGC	19.022	Down-regulation
AGC_Akt_AKT2_ST	Q13835	PKP1	P31751	AKT2	S188	G192S	192	Missense	distal	4	no	27.531	27.517	EPSD;PhosphoSitePlus	ICGC	19.022	Down-regulation
AGC_Akt_AKT2_ST	Q13835	PKP1	P31751	AKT2	S205	P204S	204	Missense	proximal	-1	no	20.966	21.049	EPSD	ICGC;COSMIC	19.022	Up-regulation
AGC_Akt_AKT2_ST	Q13835	PKP1	P31751	AKT2	S205	R202S	202	Missense	distal	-3	no	20.966	11.848	EPSD	ICGC;COSMIC	19.022	Loss
AGC_Akt_AKT2_ST	Q13835	PKP1	P31751	AKT2	S205	R202H	202	Missense	distal	-3	no	20.966	1.157	EPSD	ICGC;COSMIC	19.022	Loss
AGC_Akt_AKT2_ST	Q13835	PKP1	P31751	AKT2	S205	P203Q	203	Missense	proximal	-2	no	20.966	21.355	EPSD	ICGC;COSMIC	19.022	Up-regulation
AGC_Akt_AKT2_ST	Q13835	PKP1	P31751	AKT2	S205	P212H	212	Missense	distal	7	no	20.966	21.189	EPSD	ICGC;COSMIC	19.022	Up-regulation
AGC_Akt_AKT2_ST	Q13835	PKP1	P31751	AKT2	S233	F226I	226	Missense	distal	-7	no	22.019	21.943	EPSD	ICGC;COSMIC	19.022	Down-regulation
AGC_Akt_AKT2_ST	Q13835	PKP1	P31751	AKT2	S233	H228Y	228	Missense	distal	-5	no	22.019	22.264	EPSD	ICGC	19.022	Up-regulation
AGC_Akt_AKT2_ST	Q13835	PKP1	P31751	AKT2	S233	S229C	229	Missense	distal	-4	no	22.019	22.506	EPSD	ICGC;COSMIC	19.022	Up-regulation
AGC_Akt_AKT2_ST	Q13835	PKP1	P31751	AKT2	S233	S233Y	233	Missense	central	0	yes	22.019	0.000	EPSD	ICGC;COSMIC	19.022	Loss
AGC_Akt_AKT2_ST	Q13835	PKP1	P31751	AKT2	S233	S229Y	229	Missense	distal	-4	no	22.019	22.179	EPSD	ICGC;COSMIC	19.022	Up-regulation
AGC_Akt_AKT2_ST	Q99683	MAP3K5	P31751	AKT2	S461	G464S	464	Missense	distal	3	no	20.351	20.244	EPSD	ICGC;COSMIC	19.022	Down-regulation
AGC_Akt_AKT2_ST	Q99683	MAP3K5	P31751	AKT2	S613	E618D	618	Missense	distal	5	no	22.392	20.809	EPSD	ICGC;COSMIC	19.022	Down-regulation
AGC_Akt_AKT2_ST	Q99683	MAP3K5	P31751	AKT2	S719	S716R	716	Missense	distal	-3	no	15.685	24.802	EPSD	ICGC	19.022	Gain
AGC_Akt_AKT2_ST	O43464	HTRA2	P31751	AKT2	S13	R18Q	18	Missense	distal	5	no	25.953	25.943	EPSD	ICGC;COSMIC	19.022	Down-regulation
AGC_Akt_AKT2_ST	O43464	HTRA2	P31751	AKT2	S13	R15P	15	Missense	proximal	2	no	25.953	27.703	EPSD	ICGC;COSMIC	19.022	Up-regulation
AGC_Akt_AKT2_ST	O43464	HTRA2	P31751	AKT2	S41	S41L	41	Missense	central	0	yes	19.939	0.000	EPSD	ICGC;COSMIC	19.022	Loss
AGC_Akt_AKT2_ST	O43464	HTRA2	P31751	AKT2	S41	G42R	42	Missense	proximal	1	no	19.939	18.144	EPSD	ICGC	19.022	Loss
AGC_Akt_AKT2_ST	O43464	HTRA2	P31751	AKT2	S96	E97D	97	Missense	proximal	1	no	28.776	29.923	EPSD	ICGC	19.022	Up-regulation
AGC_Akt_AKT2_ST	O43464	HTRA2	P31751	AKT2	T242	R247L	247	Missense	distal	5	no	22.885	21.174	EPSD	ICGC;COSMIC	19.022	Down-regulation
AGC_Akt_AKT2_ST	O43464	HTRA2	P31751	AKT2	S400	G399V	399	Missense	proximal	-1	no	18.573	19.590	EPSD	ICGC	19.022	Gain
AGC_Akt_AKT2_ST	P00533	EGFR	P31751	AKT2	S925	E922A	922	Missense	distal	-3	no	11.912	19.407	EPSD	ICGC;COSMIC	19.022	Gain
AGC_Akt_AKT2_ST	P00533	EGFR	P31751	AKT2	S1120	A1118V	1118	Missense	proximal	-2	no	19.144	19.622	EPSD	ICGC;COSMIC	19.022	Up-regulation
AGC_Akt_AKT2_ST	P00533	EGFR	P31751	AKT2	S1204	Y1197C	1197	Missense	distal	-7	no	30.072	30.325	EPSD	ICGC;COSMIC	19.022	Up-regulation
AGC_Akt_AKT2_ST	P00533	EGFR	P31751	AKT2	S1204	L1198I	1198	Missense	distal	-6	no	30.072	30.149	EPSD	ICGC;COSMIC	19.022	Up-regulation
AGC_Akt_AKT2_ST	P15311	EZR	P31751	AKT2	S249	F255L	255	Missense	distal	6	no	19.336	19.945	EPSD	ICGC;COSMIC	19.022	Up-regulation
AGC_Akt_AKT2_ST	P15311	EZR	P31751	AKT2	S249	D252H	252	Missense	distal	3	no	19.336	19.197	EPSD	ICGC	19.022	Down-regulation
AGC_Akt_AKT2_ST	P15311	EZR	P31751	AKT2	T299	R293C	293	Missense	distal	-6	no	18.874	19.673	EPSD	ICGC;COSMIC;CCLE	19.022	Gain
AGC_Akt_AKT2_ST	P15311	EZR	P31751	AKT2	T332	E334K	334	Missense	proximal	2	no	24.052	24.035	EPSD	ICGC;COSMIC	19.022	Down-regulation
AGC_Akt_AKT2_ST	P15311	EZR	P31751	AKT2	S535	T533M	533	Missense	proximal	-2	no	20.541	20.413	EPSD	ICGC	19.022	Down-regulation
AGC_Akt_AKT2_ST	P15311	EZR	P31751	AKT2	T567	T567M	567	Missense	central	0	yes	27.259	0.000	PhosphoSitePlus	ICGC;COSMIC	19.022	Loss
AGC_Akt_AKT2_ST	P15311	EZR	P31751	AKT2	T567	Q573K	573	Missense	distal	6	no	27.259	27.113	PhosphoSitePlus	ICGC	19.022	Down-regulation
AGC_Akt_AKT2_ST	Q9Y3M2	CBY1	P31751	AKT2	S20	A19S	19	Missense	proximal	-1	no	23.158	22.485	PhosphoSitePlus	ICGC	19.022	Down-regulation
AGC_Akt_AKT2_ST	Q9Y3M2	CBY1	P31751	AKT2	T44	G41R	41	Missense	distal	-3	no	13.646	23.374	EPSD	ICGC;COSMIC	19.022	Gain
AGC_Akt_AKT2_ST	Q9Y3M2	CBY1	P31751	AKT2	T63	W59R	59	Missense	distal	-4	no	24.969	24.254	EPSD	ICGC;COSMIC	19.022	Down-regulation
AGC_Akt_AKT2_ST	P98170	XIAP	P31751	AKT2	S87	C90Y	90	Missense	distal	3	no	28.775	28.550	PhosphoSitePlus	ICGC;COSMIC	19.022	Down-regulation
AGC_Akt_AKT2_ST	P98170	XIAP	P31751	AKT2	S261	R268Q	268	Missense	distal	7	no	20.020	19.924	EPSD	ICGC;COSMIC	19.022	Down-regulation
AGC_Akt_AKT2_ST	Q92908	GATA6	P31751	AKT2	S24	A26S	26	Missense	proximal	2	no	20.684	20.137	EPSD	ICGC;COSMIC	19.022	Down-regulation
AGC_Akt_AKT2_ST	Q92908	GATA6	P31751	AKT2	S33	A26S	26	Missense	distal	-7	no	27.560	27.333	EPSD	ICGC;COSMIC	19.022	Down-regulation
AGC_Akt_AKT2_ST	Q92908	GATA6	P31751	AKT2	S33	P38T	38	Missense	distal	5	no	27.560	28.137	EPSD	ICGC;COSMIC	19.022	Up-regulation
AGC_Akt_AKT2_ST	Q92908	GATA6	P31751	AKT2	S33	P38H	38	Missense	distal	5	no	27.560	28.273	EPSD	ICGC;COSMIC	19.022	Up-regulation
AGC_Akt_AKT2_ST	Q92908	GATA6	P31751	AKT2	S37	P38T	38	Missense	proximal	1	no	21.620	20.941	EPSD	ICGC;COSMIC	19.022	Down-regulation
AGC_Akt_AKT2_ST	Q92908	GATA6	P31751	AKT2	S37	P38H	38	Missense	proximal	1	no	21.620	20.601	EPSD	ICGC;COSMIC	19.022	Down-regulation
AGC_Akt_AKT2_ST	Q92908	GATA6	P31751	AKT2	S377	G375D	375	Missense	proximal	-2	no	20.844	17.890	EPSD	ICGC	19.022	Loss
AGC_Akt_AKT2_ST	Q92908	GATA6	P31751	AKT2	S436	R438W	438	Missense	proximal	2	no	29.593	31.159	EPSD	ICGC;COSMIC	19.022	Up-regulation
AGC_Akt_AKT2_ST	Q14315	FLNC	P31751	AKT2	T423	G419V	419	Missense	distal	-4	no	21.423	21.232	EPSD	ICGC	19.022	Down-regulation
AGC_Akt_AKT2_ST	Q14315	FLNC	P31751	AKT2	S506	G505S	505	Missense	proximal	-1	no	18.419	19.186	EPSD	ICGC	19.022	Gain
AGC_Akt_AKT2_ST	Q14315	FLNC	P31751	AKT2	S1545	R1543Q	1543	Missense	proximal	-2	no	19.413	17.013	EPSD	ICGC	19.022	Loss
AGC_Akt_AKT2_ST	Q14315	FLNC	P31751	AKT2	S1545	A1539S	1539	Missense	distal	-6	no	19.413	19.277	EPSD	ICGC	19.022	Down-regulation
AGC_Akt_AKT2_ST	Q14315	FLNC	P31751	AKT2	S1545	S1540I	1540	Missense	distal	-5	no	19.413	20.851	EPSD	ICGC;COSMIC	19.022	Up-regulation
AGC_Akt_AKT2_ST	Q14315	FLNC	P31751	AKT2	S1940	P1941S	1941	Missense	proximal	1	no	23.719	22.788	EPSD	ICGC	19.022	Down-regulation
AGC_Akt_AKT2_ST	Q14315	FLNC	P31751	AKT2	S1985	P1990L	1990	Missense	distal	5	no	23.021	22.465	EPSD	ICGC	19.022	Down-regulation
AGC_Akt_AKT2_ST	Q14315	FLNC	P31751	AKT2	S2004	S2004F	2004	Missense	central	0	yes	20.051	0.000	EPSD	ICGC	19.022	Loss
AGC_Akt_AKT2_ST	Q14315	FLNC	P31751	AKT2	T2179	R2180H	2180	Missense	proximal	1	no	19.607	21.084	EPSD	ICGC;COSMIC	19.022	Up-regulation
AGC_Akt_AKT2_ST	Q14315	FLNC	P31751	AKT2	T2179	R2173H	2173	Missense	distal	-6	no	19.607	19.877	EPSD	ICGC;COSMIC	19.022	Up-regulation
AGC_Akt_AKT2_ST	Q14315	FLNC	P31751	AKT2	T2179	R2173Q	2173	Missense	distal	-6	no	19.607	19.583	EPSD	ICGC	19.022	Down-regulation
AGC_Akt_AKT2_ST	Q14315	FLNC	P31751	AKT2	S2181	R2180H	2180	Missense	proximal	-1	no	20.553	19.779	EPSD	ICGC;COSMIC	19.022	Down-regulation
AGC_Akt_AKT2_ST	Q14315	FLNC	P31751	AKT2	S2233	R2228L	2228	Missense	distal	-5	no	35.073	27.349	PhosphoSitePlus	ICGC;COSMIC	19.022	Down-regulation
AGC_Akt_AKT2_ST	Q14315	FLNC	P31751	AKT2	S2233	R2230C	2230	Missense	distal	-3	no	35.073	1.064	PhosphoSitePlus	ICGC	19.022	Loss
AGC_Akt_AKT2_ST	Q14315	FLNC	P31751	AKT2	S2395	V2398L	2398	Missense	distal	3	no	19.748	20.498	EPSD	ICGC;COSMIC	19.022	Up-regulation
AGC_Akt_AKT2_ST	Q14315	FLNC	P31751	AKT2	S2395	S2395P	2395	Missense	central	0	yes	19.748	0.000	EPSD	ICGC	19.022	Loss
AGC_Akt_AKT2_ST	P03372	ESR1	P31751	AKT2	S118	P114L	114	Missense	distal	-4	no	18.630	19.039	EPSD	ICGC;COSMIC	19.022	Gain
AGC_Akt_AKT2_ST	P03372	ESR1	P31751	AKT2	S167	E163Q	163	Missense	distal	-4	no	34.641	34.471	PhosphoSitePlus	ICGC;COSMIC	19.022	Down-regulation
AGC_Akt_AKT2_ST	P03372	ESR1	P31751	AKT2	S236	Q238R	238	Missense	proximal	2	no	31.635	31.116	EPSD	ICGC	19.022	Down-regulation
AGC_Akt_AKT2_ST	P03372	ESR1	P31751	AKT2	S236	L242I	242	Missense	distal	6	no	31.635	31.901	EPSD	ICGC	19.022	Up-regulation
AGC_Akt_AKT2_ST	P03372	ESR1	P31751	AKT2	S236	R233M	233	Missense	distal	-3	no	31.635	2.857	EPSD	ICGC;COSMIC	19.022	Loss
AGC_Akt_AKT2_ST	P03372	ESR1	P31751	AKT2	S282	A283V	283	Missense	proximal	1	no	21.270	19.842	EPSD	ICGC;COSMIC	19.022	Down-regulation
AGC_Akt_AKT2_ST	Q9H0H5	RACGAP1	P31751	AKT2	S144	S151F	151	Missense	distal	7	no	24.122	23.082	EPSD	ICGC	19.022	Down-regulation
AGC_Akt_AKT2_ST	Q9H0H5	RACGAP1	P31751	AKT2	S234	E231K	231	Missense	distal	-3	no	12.930	21.438	EPSD	ICGC;COSMIC	19.022	Gain
AGC_Akt_AKT2_ST	Q9H0H5	RACGAP1	P31751	AKT2	T249	R247S	247	Missense	proximal	-2	no	29.292	26.712	PhosphoSitePlus	ICGC;COSMIC	19.022	Down-regulation
AGC_Akt_AKT2_ST	Q9H0H5	RACGAP1	P31751	AKT2	T272	G276D	276	Missense	distal	4	no	19.004	19.164	EPSD	ICGC;COSMIC	19.022	Gain
AGC_Akt_AKT2_ST	Q9H0H5	RACGAP1	P31751	AKT2	S592	R597T	597	Missense	distal	5	no	21.870	21.294	EPSD	ICGC;COSMIC	19.022	Down-regulation
AGC_Akt_AKT2_ST	Q9H0H5	RACGAP1	P31751	AKT2	S600	R597T	597	Missense	distal	-3	no	22.113	9.505	EPSD	ICGC;COSMIC	19.022	Loss
AGC_Akt_AKT2_ST	Q9H0H5	RACGAP1	P31751	AKT2	S611	S613I	613	Missense	proximal	2	no	19.326	20.192	EPSD	ICGC;COSMIC	19.022	Up-regulation
AGC_Akt_AKT2_ST	Q9H0H5	RACGAP1	P31751	AKT2	T617	R621Q	621	Missense	distal	4	no	20.511	20.550	EPSD	ICGC;COSMIC	19.022	Up-regulation
AGC_Akt_AKT2_ST	Q9H0H5	RACGAP1	P31751	AKT2	T617	S613I	613	Missense	distal	-4	no	20.511	20.701	EPSD	ICGC;COSMIC	19.022	Up-regulation
AGC_Akt_AKT2_ST	O43516	WIPF1	P31751	AKT2	S135	L129F	129	Missense	distal	-6	no	23.063	23.222	EPSD	ICGC	19.022	Up-regulation
AGC_Akt_AKT2_ST	O43516	WIPF1	P31751	AKT2	S135	P140H	140	Missense	distal	5	no	23.063	23.776	EPSD	ICGC;COSMIC	19.022	Up-regulation
AGC_Akt_AKT2_ST	O43516	WIPF1	P31751	AKT2	T136	L129F	129	Missense	distal	-7	no	19.401	19.640	EPSD	ICGC	19.022	Up-regulation
AGC_Akt_AKT2_ST	O43516	WIPF1	P31751	AKT2	T136	P140H	140	Missense	distal	4	no	19.401	19.270	EPSD	ICGC;COSMIC	19.022	Down-regulation
AGC_Akt_AKT2_ST	O43516	WIPF1	P31751	AKT2	S137	P140H	140	Missense	distal	3	no	22.220	22.048	EPSD	ICGC;COSMIC	19.022	Down-regulation
AGC_Akt_AKT2_ST	O43516	WIPF1	P31751	AKT2	S145	S145G	145	Missense	central	0	yes	27.081	0.000	EPSD	ICGC;COSMIC;GDSC;CCLE	19.022	Loss
AGC_Akt_AKT2_ST	O43516	WIPF1	P31751	AKT2	S145	P151S	151	Missense	distal	6	no	27.081	27.266	EPSD	ICGC;COSMIC;GDSC;CCLE	19.022	Up-regulation
AGC_Akt_AKT2_ST	O43516	WIPF1	P31751	AKT2	S145	P140H	140	Missense	distal	-5	no	27.081	19.304	EPSD	ICGC;COSMIC	19.022	Down-regulation
AGC_Akt_AKT2_ST	O43516	WIPF1	P31751	AKT2	S145	V152G	152	Missense	distal	7	no	27.081	26.414	EPSD	ICGC;COSMIC	19.022	Down-regulation
AGC_Akt_AKT2_ST	O43516	WIPF1	P31751	AKT2	S154	P151S	151	Missense	distal	-3	no	30.343	27.503	EPSD;PhosphoSitePlus	ICGC;COSMIC;GDSC;CCLE	19.022	Down-regulation
AGC_Akt_AKT2_ST	O43516	WIPF1	P31751	AKT2	S154	S154F	154	Missense	central	0	yes	30.343	0.000	EPSD;PhosphoSitePlus	ICGC	19.022	Loss
AGC_Akt_AKT2_ST	O43516	WIPF1	P31751	AKT2	S154	V152G	152	Missense	proximal	-2	no	30.343	28.607	EPSD;PhosphoSitePlus	ICGC;COSMIC	19.022	Down-regulation
AGC_Akt_AKT2_ST	O43516	WIPF1	P31751	AKT2	S214	P217T	217	Missense	distal	3	no	21.008	20.875	EPSD	ICGC;COSMIC	19.022	Down-regulation
AGC_Akt_AKT2_ST	O43516	WIPF1	P31751	AKT2	S214	G208R	208	Missense	distal	-6	no	21.008	20.650	EPSD	ICGC;COSMIC	19.022	Down-regulation
AGC_Akt_AKT2_ST	O43516	WIPF1	P31751	AKT2	S214	R211M	211	Missense	distal	-3	no	21.008	-7.770	EPSD	ICGC;COSMIC	19.022	Loss
AGC_Akt_AKT2_ST	O43516	WIPF1	P31751	AKT2	S214	P207S	207	Missense	distal	-7	no	21.008	20.703	EPSD	ICGC;COSMIC	19.022	Down-regulation
AGC_Akt_AKT2_ST	O43516	WIPF1	P31751	AKT2	S214	P220H	220	Missense	distal	6	no	21.008	21.123	EPSD	ICGC;COSMIC	19.022	Up-regulation
AGC_Akt_AKT2_ST	O43516	WIPF1	P31751	AKT2	S238	G232V	232	Missense	distal	-6	no	23.282	23.057	EPSD	ICGC	19.022	Down-regulation
AGC_Akt_AKT2_ST	O43516	WIPF1	P31751	AKT2	S238	P239S	239	Missense	proximal	1	no	23.282	22.351	EPSD	ICGC	19.022	Down-regulation
AGC_Akt_AKT2_ST	O43516	WIPF1	P31751	AKT2	S244	P239S	239	Missense	distal	-5	no	21.360	18.297	EPSD	ICGC	19.022	Loss
AGC_Akt_AKT2_ST	O43516	WIPF1	P31751	AKT2	S296	P298L	298	Missense	proximal	2	no	23.836	23.365	EPSD	ICGC;COSMIC	19.022	Down-regulation
AGC_Akt_AKT2_ST	O43516	WIPF1	P31751	AKT2	S296	P295H	295	Missense	proximal	-1	no	23.836	24.112	EPSD	ICGC;COSMIC	19.022	Up-regulation
AGC_Akt_AKT2_ST	O43516	WIPF1	P31751	AKT2	S296	N290K	290	Missense	distal	-6	no	23.836	23.941	EPSD	ICGC	19.022	Up-regulation
AGC_Akt_AKT2_ST	O43516	WIPF1	P31751	AKT2	S296	R299L	299	Missense	distal	3	no	23.836	24.799	EPSD	ICGC;COSMIC	19.022	Up-regulation
AGC_Akt_AKT2_ST	O43516	WIPF1	P31751	AKT2	S296	P292H	292	Missense	distal	-4	no	23.836	24.134	EPSD	ICGC;COSMIC	19.022	Up-regulation
AGC_Akt_AKT2_ST	O43516	WIPF1	P31751	AKT2	S301	P298L	298	Missense	distal	-3	no	20.577	18.757	EPSD	ICGC;COSMIC	19.022	Loss
AGC_Akt_AKT2_ST	O43516	WIPF1	P31751	AKT2	S301	P295H	295	Missense	distal	-6	no	20.577	20.205	EPSD	ICGC;COSMIC	19.022	Down-regulation
AGC_Akt_AKT2_ST	O43516	WIPF1	P31751	AKT2	S301	R299L	299	Missense	proximal	-2	no	20.577	18.127	EPSD	ICGC;COSMIC	19.022	Loss
AGC_Akt_AKT2_ST	O43516	WIPF1	P31751	AKT2	S340	T345K	345	Missense	distal	5	no	22.692	23.012	EPSD	ICGC;COSMIC	19.022	Up-regulation
AGC_Akt_AKT2_ST	O43516	WIPF1	P31751	AKT2	S340	P347S	347	Missense	distal	7	no	22.692	23.017	EPSD	ICGC	19.022	Up-regulation
AGC_Akt_AKT2_ST	O43516	WIPF1	P31751	AKT2	S340	P347L	347	Missense	distal	7	no	22.692	22.388	EPSD	ICGC;COSMIC	19.022	Down-regulation
AGC_Akt_AKT2_ST	O43516	WIPF1	P31751	AKT2	S342	T345K	345	Missense	distal	3	no	20.655	19.540	EPSD	ICGC;COSMIC	19.022	Down-regulation
AGC_Akt_AKT2_ST	O43516	WIPF1	P31751	AKT2	S342	P347S	347	Missense	distal	5	no	20.655	21.460	EPSD	ICGC	19.022	Up-regulation
AGC_Akt_AKT2_ST	O43516	WIPF1	P31751	AKT2	S342	P347L	347	Missense	distal	5	no	20.655	20.099	EPSD	ICGC;COSMIC	19.022	Down-regulation
AGC_Akt_AKT2_ST	O43516	WIPF1	P31751	AKT2	S350	T345K	345	Missense	distal	-5	no	17.683	21.277	EPSD	ICGC;COSMIC	19.022	Gain
AGC_Akt_AKT2_ST	O43516	WIPF1	P31751	AKT2	S354	S350L	350	Missense	distal	-4	no	21.719	22.011	EPSD	ICGC;COSMIC	19.022	Up-regulation
AGC_Akt_AKT2_ST	O43516	WIPF1	P31751	AKT2	S354	P359S	359	Missense	distal	5	no	21.719	22.525	EPSD	ICGC;COSMIC	19.022	Up-regulation
AGC_Akt_AKT2_ST	O43516	WIPF1	P31751	AKT2	S354	R353S	353	Missense	proximal	-1	no	21.719	20.753	EPSD	ICGC;COSMIC	19.022	Down-regulation
AGC_Akt_AKT2_ST	O43516	WIPF1	P31751	AKT2	S354	P347S	347	Missense	distal	-7	no	21.719	21.414	EPSD	ICGC	19.022	Down-regulation
AGC_Akt_AKT2_ST	O43516	WIPF1	P31751	AKT2	S354	L357F	357	Missense	distal	3	no	21.719	22.142	EPSD	ICGC	19.022	Up-regulation
AGC_Akt_AKT2_ST	O43516	WIPF1	P31751	AKT2	S354	P347L	347	Missense	distal	-7	no	21.719	21.823	EPSD	ICGC;COSMIC	19.022	Up-regulation
AGC_Akt_AKT2_ST	O43516	WIPF1	P31751	AKT2	S376	D371E	371	Missense	distal	-5	no	3.848	22.111	EPSD	ICGC;COSMIC	19.022	Gain
AGC_Akt_AKT2_ST	O43516	WIPF1	P31751	AKT2	S390	R393L	393	Missense	distal	3	no	18.189	19.152	EPSD	ICGC;COSMIC	19.022	Gain
AGC_Akt_AKT2_ST	O43516	WIPF1	P31751	AKT2	S392	A397S	397	Missense	distal	5	no	20.440	20.344	EPSD	ICGC	19.022	Down-regulation
AGC_Akt_AKT2_ST	O43516	WIPF1	P31751	AKT2	S392	T398N	398	Missense	distal	6	no	20.440	20.460	EPSD	ICGC	19.022	Up-regulation
AGC_Akt_AKT2_ST	O43516	WIPF1	P31751	AKT2	S392	A394V	394	Missense	proximal	2	no	20.440	20.283	EPSD	ICGC;GDSC;CCLE	19.022	Down-regulation
AGC_Akt_AKT2_ST	O43516	WIPF1	P31751	AKT2	S392	R393Q	393	Missense	proximal	1	no	20.440	21.278	EPSD	ICGC;COSMIC	19.022	Up-regulation
AGC_Akt_AKT2_ST	O43516	WIPF1	P31751	AKT2	S392	R393L	393	Missense	proximal	1	no	20.440	22.111	EPSD	ICGC;COSMIC	19.022	Up-regulation
AGC_Akt_AKT2_ST	O43516	WIPF1	P31751	AKT2	S392	T398I	398	Missense	distal	6	no	20.440	20.388	EPSD	ICGC;COSMIC	19.022	Down-regulation
AGC_Akt_AKT2_ST	O43516	WIPF1	P31751	AKT2	T398	A397S	397	Missense	proximal	-1	no	27.716	27.043	PhosphoSitePlus;EPSD	ICGC	19.022	Down-regulation
AGC_Akt_AKT2_ST	O43516	WIPF1	P31751	AKT2	T398	T398N	398	Missense	central	0	yes	27.716	0.000	PhosphoSitePlus;EPSD	ICGC	19.022	Loss
AGC_Akt_AKT2_ST	O43516	WIPF1	P31751	AKT2	T398	A394V	394	Missense	distal	-4	no	27.716	27.714	PhosphoSitePlus;EPSD	ICGC;GDSC;CCLE	19.022	Down-regulation
AGC_Akt_AKT2_ST	O43516	WIPF1	P31751	AKT2	T398	R393Q	393	Missense	distal	-5	no	27.716	23.383	PhosphoSitePlus;EPSD	ICGC;COSMIC	19.022	Down-regulation
AGC_Akt_AKT2_ST	O43516	WIPF1	P31751	AKT2	T398	R393L	393	Missense	distal	-5	no	27.716	19.992	PhosphoSitePlus;EPSD	ICGC;COSMIC	19.022	Down-regulation
AGC_Akt_AKT2_ST	O43516	WIPF1	P31751	AKT2	T398	T398I	398	Missense	central	0	yes	27.716	0.000	PhosphoSitePlus;EPSD	ICGC;COSMIC	19.022	Loss
AGC_Akt_AKT2_ST	O43516	WIPF1	P31751	AKT2	S405	S409G	409	Missense	distal	4	no	21.647	21.661	EPSD	ICGC	19.022	Up-regulation
AGC_Akt_AKT2_ST	O43516	WIPF1	P31751	AKT2	S405	T398N	398	Missense	distal	-7	no	21.647	21.623	EPSD	ICGC	19.022	Down-regulation
AGC_Akt_AKT2_ST	O43516	WIPF1	P31751	AKT2	S405	T398I	398	Missense	distal	-7	no	21.647	22.048	EPSD	ICGC;COSMIC	19.022	Up-regulation
AGC_Akt_AKT2_ST	O43516	WIPF1	P31751	AKT2	S424	D421G	421	Missense	distal	-3	no	-9.003	19.041	EPSD	ICGC;COSMIC	19.022	Gain
AGC_Akt_AKT2_ST	O43516	WIPF1	P31751	AKT2	S434	R438I	438	Missense	distal	4	no	19.834	20.158	EPSD	ICGC;COSMIC	19.022	Up-regulation
AGC_Akt_AKT2_ST	O43516	WIPF1	P31751	AKT2	S434	P430L	430	Missense	distal	-4	no	19.834	20.242	EPSD	ICGC;COSMIC	19.022	Up-regulation
AGC_Akt_AKT2_ST	O43516	WIPF1	P31751	AKT2	T435	R438I	438	Missense	distal	3	no	24.674	25.648	EPSD	ICGC;COSMIC	19.022	Up-regulation
AGC_Akt_AKT2_ST	O43516	WIPF1	P31751	AKT2	T435	P430L	430	Missense	distal	-5	no	24.674	21.047	EPSD	ICGC;COSMIC	19.022	Down-regulation
AGC_Akt_AKT2_ST	O43516	WIPF1	P31751	AKT2	S488	R491I	491	Missense	distal	3	no	24.005	24.979	EPSD	ICGC;COSMIC	19.022	Up-regulation
AGC_Akt_AKT2_ST	O43516	WIPF1	P31751	AKT2	S488	A495D	495	Missense	distal	7	no	24.005	23.441	EPSD	ICGC	19.022	Down-regulation
AGC_Akt_AKT2_ST	Q96F86	EDC3	P31751	AKT2	S253	N249K	249	Missense	distal	-4	no	20.180	20.267	EPSD	ICGC;COSMIC	19.022	Up-regulation
AGC_Akt_AKT2_ST	Q96F86	EDC3	P31751	AKT2	S253	H246N	246	Missense	distal	-7	no	20.180	19.947	EPSD	ICGC;COSMIC	19.022	Down-regulation
AGC_Akt_AKT2_ST	Q99623	PHB2	P31751	AKT2	T169	A172S	172	Missense	distal	3	no	19.307	18.814	EPSD	ICGC;COSMIC	19.022	Loss
AGC_Akt_AKT2_ST	Q92945	KHSRP	P31751	AKT2	S144	T146K	146	Missense	proximal	2	no	25.523	24.657	EPSD	ICGC	19.022	Down-regulation
AGC_Akt_AKT2_ST	Q92945	KHSRP	P31751	AKT2	S144	T143N	143	Missense	proximal	-1	no	25.523	25.623	EPSD	ICGC	19.022	Up-regulation
AGC_Akt_AKT2_ST	Q92945	KHSRP	P31751	AKT2	S144	E148D	148	Missense	distal	4	no	25.523	25.699	EPSD	ICGC	19.022	Up-regulation
AGC_Akt_AKT2_ST	Q92945	KHSRP	P31751	AKT2	S144	R150S	150	Missense	distal	6	no	25.523	24.310	EPSD	ICGC;COSMIC	19.022	Down-regulation
AGC_Akt_AKT2_ST	Q92945	KHSRP	P31751	AKT2	S193	T195K	195	Missense	proximal	2	no	28.142	27.276	PhosphoSitePlus	ICGC	19.022	Down-regulation
AGC_Akt_AKT2_ST	Q92945	KHSRP	P31751	AKT2	S193	S200Y	200	Missense	distal	7	no	28.142	27.717	PhosphoSitePlus	ICGC	19.022	Down-regulation
AGC_Akt_AKT2_ST	Q92945	KHSRP	P31751	AKT2	S670	P668A	668	Missense	proximal	-2	no	21.412	23.008	EPSD	ICGC;COSMIC	19.022	Up-regulation
AGC_Akt_AKT2_ST	O60331	PIP5K1C	P31751	AKT2	S539	P536H	536	Missense	distal	-3	no	21.962	8.431	EPSD	ICGC	19.022	Loss
AGC_Akt_AKT2_ST	O60331	PIP5K1C	P31751	AKT2	S539	S544L	544	Missense	distal	5	no	21.962	20.601	EPSD	ICGC;COSMIC	19.022	Down-regulation
AGC_Akt_AKT2_ST	O60331	PIP5K1C	P31751	AKT2	S541	P536H	536	Missense	distal	-5	no	25.896	18.119	EPSD	ICGC	19.022	Loss
AGC_Akt_AKT2_ST	O60331	PIP5K1C	P31751	AKT2	S541	S544L	544	Missense	distal	3	no	25.896	26.686	EPSD	ICGC;COSMIC	19.022	Up-regulation
AGC_Akt_AKT2_ST	O60331	PIP5K1C	P31751	AKT2	T543	P536H	536	Missense	distal	-7	no	22.618	22.692	EPSD	ICGC	19.022	Up-regulation
AGC_Akt_AKT2_ST	O60331	PIP5K1C	P31751	AKT2	T543	S544L	544	Missense	proximal	1	no	22.618	22.724	EPSD	ICGC;COSMIC	19.022	Up-regulation
AGC_Akt_AKT2_ST	O60331	PIP5K1C	P31751	AKT2	T553	T553A	553	Missense	central	0	yes	28.809	0.000	EPSD	ICGC	19.022	Loss
AGC_Akt_AKT2_ST	O60331	PIP5K1C	P31751	AKT2	S555	P562L	562	Missense	distal	7	no	30.031	29.727	PhosphoSitePlus	ICGC	19.022	Down-regulation
AGC_Akt_AKT2_ST	O60331	PIP5K1C	P31751	AKT2	S555	T553A	553	Missense	proximal	-2	no	30.031	32.292	PhosphoSitePlus	ICGC	19.022	Up-regulation
AGC_Akt_AKT2_ST	O60331	PIP5K1C	P31751	AKT2	S556	T553A	553	Missense	distal	-3	no	18.471	23.103	EPSD	ICGC	19.022	Gain
AGC_Akt_AKT2_ST	O60331	PIP5K1C	P31751	AKT2	S650	W647L	647	Missense	distal	-3	no	19.210	26.841	EPSD	ICGC;COSMIC	19.022	Up-regulation
AGC_Akt_AKT2_ST	O60331	PIP5K1C	P31751	AKT2	S650	R645M	645	Missense	distal	-5	no	19.210	0.696	EPSD	ICGC;COSMIC	19.022	Loss
AGC_Akt_AKT2_ST	O60331	PIP5K1C	P31751	AKT2	S650	R645G	645	Missense	distal	-5	no	19.210	12.915	EPSD	ICGC;COSMIC;CCLE	19.022	Loss
AGC_Akt_AKT2_ST	O15111	CHUK	P31751	AKT2	T593	R599S	599	Missense	distal	6	no	20.968	19.755	EPSD	ICGC;COSMIC	19.022	Down-regulation
AGC_Akt_AKT2_ST	Q86YS7	C2CD5	P31751	AKT2	S197	L203M	203	Missense	distal	6	no	34.053	34.151	PhosphoSitePlus	ICGC	19.022	Up-regulation
AGC_Akt_AKT2_ST	Q86YS7	C2CD5	P31751	AKT2	S197	E190D	190	Missense	distal	-7	no	34.053	34.653	PhosphoSitePlus	ICGC;COSMIC	19.022	Up-regulation
AGC_Akt_AKT2_ST	Q86YS7	C2CD5	P31751	AKT2	S250	L255F	255	Missense	distal	5	no	24.085	24.311	EPSD	ICGC;COSMIC	19.022	Up-regulation
AGC_Akt_AKT2_ST	Q86YS7	C2CD5	P31751	AKT2	S262	P261Q	261	Missense	proximal	-1	no	19.614	20.184	EPSD	ICGC;COSMIC	19.022	Up-regulation
AGC_Akt_AKT2_ST	Q86YS7	C2CD5	P31751	AKT2	S262	P269L	269	Missense	distal	7	no	19.614	19.310	EPSD	ICGC	19.022	Down-regulation
AGC_Akt_AKT2_ST	Q86YS7	C2CD5	P31751	AKT2	S262	L255F	255	Missense	distal	-7	no	19.614	19.854	EPSD	ICGC;COSMIC	19.022	Up-regulation
AGC_Akt_AKT2_ST	Q86YS7	C2CD5	P31751	AKT2	S262	P269Q	269	Missense	distal	7	no	19.614	19.951	EPSD	ICGC;COSMIC	19.022	Up-regulation
AGC_Akt_AKT2_ST	Q86YS7	C2CD5	P31751	AKT2	S652	R653S	653	Missense	proximal	1	no	19.835	21.400	EPSD	ICGC	19.022	Up-regulation
AGC_Akt_AKT2_ST	Q86YS7	C2CD5	P31751	AKT2	S659	R653S	653	Missense	distal	-6	no	27.898	28.024	EPSD	ICGC	19.022	Up-regulation
AGC_Akt_AKT2_ST	Q7Z6J0	SH3RF1	P31751	AKT2	S125	P129Q	129	Missense	distal	4	no	29.209	28.888	EPSD	ICGC;COSMIC	19.022	Down-regulation
AGC_Akt_AKT2_ST	Q7Z6J0	SH3RF1	P31751	AKT2	S125	P121T	121	Missense	distal	-4	no	29.209	29.326	EPSD	ICGC	19.022	Up-regulation
AGC_Akt_AKT2_ST	Q7Z6J0	SH3RF1	P31751	AKT2	S125	V130L	130	Missense	distal	5	no	29.209	27.983	EPSD	ICGC;COSMIC	19.022	Down-regulation
AGC_Akt_AKT2_ST	Q7Z6J0	SH3RF1	P31751	AKT2	S125	G132V	132	Missense	distal	7	no	29.209	29.876	EPSD	ICGC;COSMIC	19.022	Up-regulation
AGC_Akt_AKT2_ST	Q7Z6J0	SH3RF1	P31751	AKT2	T509	V508G	508	Missense	proximal	-1	no	25.931	24.915	EPSD	ICGC;COSMIC;GDSC	19.022	Down-regulation
AGC_Akt_AKT2_ST	Q7Z6J0	SH3RF1	P31751	AKT2	T529	S534F	534	Missense	distal	5	no	19.448	18.312	EPSD	ICGC;COSMIC	19.022	Loss
AGC_Akt_AKT2_ST	Q7Z6J0	SH3RF1	P31751	AKT2	T684	P687A	687	Missense	distal	3	no	20.214	20.032	EPSD	ICGC	19.022	Down-regulation
AGC_Akt_AKT2_ST	Q7Z6J0	SH3RF1	P31751	AKT2	S692	P687A	687	Missense	distal	-5	no	23.212	21.549	EPSD	ICGC	19.022	Down-regulation
AGC_Akt_AKT2_ST	Q7Z6J0	SH3RF1	P31751	AKT2	S727	G725V	725	Missense	proximal	-2	no	18.805	20.541	EPSD	ICGC;COSMIC	19.022	Gain
AGC_Akt_AKT2_ST	Q7Z6J0	SH3RF1	P31751	AKT2	S735	P737L	737	Missense	proximal	2	no	27.962	27.491	EPSD	ICGC	19.022	Down-regulation
AGC_Akt_AKT2_ST	Q15118	PDK1	P31751	AKT2	S35	S30P	30	Missense	distal	-5	no	17.444	20.507	EPSD	ICGC	19.022	Gain
AGC_Akt_AKT2_ST	Q15118	PDK1	P31751	AKT2	T346	P351L	351	Missense	distal	5	no	28.433	27.877	PhosphoSitePlus	ICGC;COSMIC	19.022	Down-regulation
AGC_Akt_AKT2_ST	Q15118	PDK1	P31751	AKT2	T346	R343L	343	Missense	distal	-3	no	28.433	20.336	PhosphoSitePlus	ICGC	19.022	Down-regulation
AGC_Akt_AKT2_ST	Q15118	PDK1	P31751	AKT2	T346	A353S	353	Missense	distal	7	no	28.433	28.197	PhosphoSitePlus	ICGC	19.022	Down-regulation
AGC_Akt_AKT2_ST	Q15118	PDK1	P31751	AKT2	S393	T394A	394	Missense	proximal	1	no	21.110	21.008	EPSD	ICGC;COSMIC	19.022	Down-regulation
AGC_Akt_AKT2_ST	P04406	GAPDH	P31751	AKT2	T19	I14S	14	Missense	distal	-5	no	22.837	21.399	EPSD	ICGC	19.022	Down-regulation
AGC_Akt_AKT2_ST	P04406	GAPDH	P31751	AKT2	S25	I30L	30	Missense	distal	5	no	20.612	20.363	EPSD	ICGC;COSMIC	19.022	Down-regulation
AGC_Akt_AKT2_ST	P04406	GAPDH	P31751	AKT2	S25	A32S	32	Missense	distal	7	no	20.612	20.376	EPSD	ICGC	19.022	Down-regulation
CMGC_DYRK_HIPK_HIPK3_ST	Q9UER7	DAXX	Q9H422	HIPK3	S178	R182S	182	Missense	distal	4	no	4.314	4.256	EPSD	ICGC;COSMIC	1.096	Down-regulation
CMGC_DYRK_HIPK_HIPK3_ST	Q9UER7	DAXX	Q9H422	HIPK3	S178	G183V	183	Missense	distal	5	no	4.314	4.313	EPSD	ICGC;COSMIC	1.096	Down-regulation
CMGC_DYRK_HIPK_HIPK3_ST	Q9UER7	DAXX	Q9H422	HIPK3	S184	R182S	182	Missense	proximal	-2	no	1.097	1.010	EPSD	ICGC;COSMIC	1.096	Loss
CMGC_DYRK_HIPK_HIPK3_ST	Q9UER7	DAXX	Q9H422	HIPK3	S184	G183V	183	Missense	proximal	-1	no	1.097	1.085	EPSD	ICGC;COSMIC	1.096	Loss
CMGC_DYRK_HIPK_HIPK3_ST	Q9UER7	DAXX	Q9H422	HIPK3	S561	S561N	561	Missense	central	0	yes	4.001	0.000	EPSD	ICGC;COSMIC	1.096	Loss
CMGC_DYRK_HIPK_HIPK3_ST	Q9UER7	DAXX	Q9H422	HIPK3	T599	E602D	602	Missense	distal	3	no	1.492	1.460	EPSD	ICGC	1.096	Down-regulation
CMGC_DYRK_HIPK_HIPK3_ST	Q9UER7	DAXX	Q9H422	HIPK3	S618	V617F	617	Missense	proximal	-1	no	3.837	3.797	EPSD	ICGC;COSMIC	1.096	Down-regulation
CMGC_DYRK_HIPK_HIPK3_ST	Q9UER7	DAXX	Q9H422	HIPK3	S618	V617I	617	Missense	proximal	-1	no	3.837	3.839	EPSD	ICGC;COSMIC	1.096	Up-regulation
CMGC_DYRK_HIPK_HIPK3_ST	Q9UER7	DAXX	Q9H422	HIPK3	S668	P670H	670	Missense	proximal	2	no	4.666	4.656	PhosphoSitePlus	ICGC;COSMIC	1.096	Down-regulation
CMGC_DYRK_HIPK_HIPK3_ST	Q9UER7	DAXX	Q9H422	HIPK3	S668	S671P	671	Missense	distal	3	no	4.666	4.625	PhosphoSitePlus	ICGC;COSMIC;GDSC;CCLE	1.096	Down-regulation
CMGC_DYRK_HIPK_HIPK3_ST	Q9UER7	DAXX	Q9H422	HIPK3	S671	P678L	678	Missense	distal	7	no	3.219	3.107	EPSD	ICGC	1.096	Down-regulation
CMGC_DYRK_HIPK_HIPK3_ST	Q9UER7	DAXX	Q9H422	HIPK3	S671	P670H	670	Missense	proximal	-1	no	3.219	3.263	EPSD	ICGC;COSMIC	1.096	Up-regulation
CMGC_DYRK_HIPK_HIPK3_ST	Q9UER7	DAXX	Q9H422	HIPK3	S671	S671P	671	Missense	central	0	yes	3.219	0.000	EPSD	ICGC;COSMIC;GDSC;CCLE	1.096	Loss
CMGC_DYRK_HIPK_HIPK3_ST	Q9UER7	DAXX	Q9H422	HIPK3	S688	T684M	684	Missense	distal	-4	no	4.728	4.712	EPSD	ICGC;COSMIC	1.096	Down-regulation
CMGC_DYRK_HIPK_HIPK3_ST	Q9UER7	DAXX	Q9H422	HIPK3	S702	L698H	698	Missense	distal	-4	no	4.960	4.968	EPSD	ICGC;COSMIC	1.096	Up-regulation
AGC_PKC_PKCa_PRKCB_ST	Q96PH1	NOX5	P05771	PRKCB	S536	T540A	540	Missense	distal	4	no	4.376	3.933	EPSD	ICGC	0.942	Down-regulation
AGC_PKC_PKCa_PRKCB_ST	Q96PH1	NOX5	P05771	PRKCB	S536	R530H	530	Missense	distal	-6	no	4.376	4.131	EPSD	ICGC;COSMIC	0.942	Down-regulation
AGC_PKC_PKCa_PRKCB_ST	Q96PH1	NOX5	P05771	PRKCB	T540	T540A	540	Missense	central	0	yes	5.403	0.000	EPSD	ICGC	0.942	Loss
AGC_PKC_PKCa_PRKCB_ST	Q96PH1	NOX5	P05771	PRKCB	S544	T540A	540	Missense	distal	-4	no	7.783	7.887	EPSD	ICGC	0.942	Up-regulation
AGC_PKC_PKCa_PRKCB_ST	P04083	ANXA1	P05771	PRKCB	T70	R77H	77	Missense	distal	7	no	0.924	1.150	EPSD	ICGC;COSMIC;CCLE	0.942	Gain
AGC_PKC_PKCa_PRKCB_ST	P04083	ANXA1	P05771	PRKCB	T70	R77L	77	Missense	distal	7	no	0.924	1.154	EPSD	ICGC	0.942	Gain
AGC_PKC_PKCa_PRKCB_ST	P10636	MAPT	P05771	PRKCB	S171	R164T	164	Missense	distal	-7	no	2.924	3.136	EPSD	ICGC;COSMIC	0.942	Up-regulation
AGC_PKC_PKCa_PRKCB_ST	P10636	MAPT	P05771	PRKCB	S171	A166T	166	Missense	distal	-5	no	2.924	2.933	EPSD	ICGC	0.942	Up-regulation
AGC_PKC_PKCa_PRKCB_ST	P10636	MAPT	P05771	PRKCB	S214	G208C	208	Missense	distal	-6	no	1.656	1.653	EPSD	ICGC;COSMIC	0.942	Down-regulation
AGC_PKC_PKCa_PRKCB_ST	P10636	MAPT	P05771	PRKCB	S214	R211S	211	Missense	distal	-3	no	1.656	-1.741	EPSD	ICGC;COSMIC	0.942	Loss
AGC_PKC_PKCa_PRKCB_ST	P10636	MAPT	P05771	PRKCB	S214	G213E	213	Missense	proximal	-1	no	1.656	1.868	EPSD	ICGC;COSMIC	0.942	Up-regulation
AGC_PKC_PKCa_PRKCB_ST	P10636	MAPT	P05771	PRKCB	S355	A349T	349	Missense	distal	-6	no	3.476	3.617	EPSD	ICGC;COSMIC	0.942	Up-regulation
AGC_PKC_PKCa_PRKCB_ST	P10636	MAPT	P05771	PRKCB	S369	R364W	364	Missense	distal	-5	no	3.530	3.152	EPSD	ICGC;COSMIC	0.942	Down-regulation
AGC_PKC_PKCa_PRKCB_ST	P10636	MAPT	P05771	PRKCB	S369	P363L	363	Missense	distal	-6	no	3.530	3.546	EPSD	ICGC	0.942	Up-regulation
AGC_PKC_PKCa_PRKCB_ST	P10636	MAPT	P05771	PRKCB	S438	Y441H	441	Missense	distal	3	no	1.209	1.183	EPSD	ICGC;COSMIC	0.942	Down-regulation
AGC_PKC_PKCa_PRKCB_ST	P10636	MAPT	P05771	PRKCB	S519	G521R	521	Missense	proximal	2	no	-6.925	1.809	EPSD	ICGC;COSMIC	0.942	Gain
AGC_PKC_PKCa_PRKCB_ST	P10636	MAPT	P05771	PRKCB	S525	G521R	521	Missense	distal	-4	no	1.150	0.732	EPSD	ICGC;COSMIC	0.942	Loss
AGC_PKC_PKCa_PRKCB_ST	P05107	ITGB2	P05771	PRKCB	T118	R121L	121	Missense	distal	3	no	4.279	3.193	EPSD	ICGC;COSMIC	0.942	Down-regulation
AGC_PKC_PKCa_PRKCB_ST	P05107	ITGB2	P05771	PRKCB	S496	S496R	496	Missense	central	0	yes	3.467	0.000	EPSD	ICGC	0.942	Loss
AGC_PKC_PKCa_PRKCB_ST	P05107	ITGB2	P05771	PRKCB	S496	S489R	489	Missense	distal	-7	no	3.467	3.197	EPSD	ICGC	0.942	Down-regulation
AGC_PKC_PKCa_PRKCB_ST	P28799	GRN	P05771	PRKCB	T18	A16S	16	Missense	proximal	-2	no	1.080	0.920	EPSD	ICGC	0.942	Loss
AGC_PKC_PKCa_PRKCB_ST	P28799	GRN	P05771	PRKCB	S435	M429I	429	Missense	distal	-6	no	4.263	4.257	EPSD	ICGC;COSMIC	0.942	Down-regulation
AGC_PKC_PKCa_PRKCB_ST	P05771	PRKCB	P05771	PRKCB	S16	E12D	12	Missense	distal	-4	no	2.322	2.428	EPSD	ICGC;COSMIC	0.942	Up-regulation
AGC_PKC_PKCa_PRKCB_ST	P05771	PRKCB	P05771	PRKCB	S16	P10T	10	Missense	distal	-6	no	2.322	2.499	EPSD	ICGC;COSMIC	0.942	Up-regulation
AGC_PKC_PKCa_PRKCB_ST	P05771	PRKCB	P05771	PRKCB	T17	E12D	12	Missense	distal	-5	no	3.564	3.537	EPSD	ICGC;COSMIC	0.942	Down-regulation
AGC_PKC_PKCa_PRKCB_ST	P05771	PRKCB	P05771	PRKCB	T17	G24V	24	Missense	distal	7	no	3.564	3.495	EPSD	ICGC;COSMIC;CCLE	0.942	Down-regulation
AGC_PKC_PKCa_PRKCB_ST	P05771	PRKCB	P05771	PRKCB	T17	P10T	10	Missense	distal	-7	no	3.564	3.380	EPSD	ICGC;COSMIC	0.942	Down-regulation
AGC_PKC_PKCa_PRKCB_ST	P05771	PRKCB	P05771	PRKCB	T40	T40I	40	Missense	central	0	yes	3.397	0.000	EPSD	ICGC;COSMIC;GDSC;CCLE	0.942	Loss
AGC_PKC_PKCa_PRKCB_ST	P05771	PRKCB	P05771	PRKCB	T40	F44I	44	Missense	distal	4	no	3.397	3.688	EPSD	ICGC;COSMIC	0.942	Up-regulation
AGC_PKC_PKCa_PRKCB_ST	P05771	PRKCB	P05771	PRKCB	T48	F44I	44	Missense	distal	-4	no	2.065	2.058	EPSD	ICGC;COSMIC	0.942	Down-regulation
AGC_PKC_PKCa_PRKCB_ST	P05771	PRKCB	P05771	PRKCB	S111	C118F	118	Missense	distal	7	no	2.681	2.711	EPSD	ICGC	0.942	Up-regulation
AGC_PKC_PKCa_PRKCB_ST	P05771	PRKCB	P05771	PRKCB	S111	D116G	116	Missense	distal	5	no	2.681	2.440	EPSD	ICGC	0.942	Down-regulation
AGC_PKC_PKCa_PRKCB_ST	P05771	PRKCB	P05771	PRKCB	S208	S206R	206	Missense	proximal	-2	no	0.458	2.411	EPSD	ICGC	0.942	Gain
AGC_PKC_PKCa_PRKCB_ST	P05771	PRKCB	P05771	PRKCB	T314	K315T	315	Missense	proximal	1	no	1.587	-0.386	EPSD	ICGC	0.942	Loss
AGC_PKC_PKCa_PRKCB_ST	P05771	PRKCB	P05771	PRKCB	T314	A308S	308	Missense	distal	-6	no	1.587	1.664	EPSD	ICGC	0.942	Up-regulation
AGC_PKC_PKCa_PRKCB_ST	P05771	PRKCB	P05771	PRKCB	T314	R307M	307	Missense	distal	-7	no	1.587	1.964	EPSD	ICGC;COSMIC	0.942	Up-regulation
AGC_PKC_PKCa_PRKCB_ST	P05771	PRKCB	P05771	PRKCB	T500	G495V	495	Missense	distal	-5	no	2.613	2.633	EPSD	ICGC;COSMIC	0.942	Up-regulation
AGC_PKC_PKCa_PRKCB_ST	P05771	PRKCB	P05771	PRKCB	T500	K499N	499	Missense	proximal	-1	no	2.613	2.330	EPSD	ICGC;COSMIC	0.942	Down-regulation
AGC_PKC_PKCa_PRKCB_ST	P29353	SHC1	P05771	PRKCB	S54	G51R	51	Missense	distal	-3	no	-2.854	1.361	EPSD	ICGC;COSMIC	0.942	Gain
AGC_PKC_PKCa_PRKCB_ST	P29353	SHC1	P05771	PRKCB	S139	P144S	144	Missense	distal	5	no	3.625	3.681	EPSD;PhosphoSitePlus	ICGC;COSMIC	0.942	Up-regulation
AGC_PKC_PKCa_PRKCB_ST	P29353	SHC1	P05771	PRKCB	S139	R136S	136	Missense	distal	-3	no	3.625	0.228	EPSD;PhosphoSitePlus	ICGC	0.942	Loss
AGC_PKC_PKCa_PRKCB_ST	P29353	SHC1	P05771	PRKCB	S139	H137Q	137	Missense	proximal	-2	no	3.625	4.668	EPSD;PhosphoSitePlus	ICGC	0.942	Up-regulation
AGC_PKC_PKCa_PRKCB_ST	P29353	SHC1	P05771	PRKCB	S139	R136L	136	Missense	distal	-3	no	3.625	-0.532	EPSD;PhosphoSitePlus	ICGC;COSMIC	0.942	Loss
AGC_PKC_PKCa_PRKCB_ST	P29353	SHC1	P05771	PRKCB	S213	P215A	215	Missense	proximal	2	no	4.082	1.914	PhosphoSitePlus;EPSD	ICGC	0.942	Down-regulation
AGC_PKC_PKCa_PRKCB_ST	P29353	SHC1	P05771	PRKCB	S213	R214S	214	Missense	proximal	1	no	4.082	2.058	PhosphoSitePlus;EPSD	ICGC;COSMIC	0.942	Down-regulation
AGC_PKC_PKCa_PRKCB_ST	Q03721	KCNC4	P05771	PRKCB	S9	K14N	14	Missense	distal	5	no	4.330	3.957	EPSD;PhosphoSitePlus	ICGC	0.942	Down-regulation
AGC_PKC_PKCa_PRKCB_ST	Q03721	KCNC4	P05771	PRKCB	S15	K14N	14	Missense	proximal	-1	no	1.298	1.015	EPSD;PhosphoSitePlus	ICGC	0.942	Down-regulation
AGC_PKC_PKCa_PRKCB_ST	Q03721	KCNC4	P05771	PRKCB	S21	K14N	14	Missense	distal	-7	no	4.869	5.171	EPSD;PhosphoSitePlus	ICGC	0.942	Up-regulation
AGC_PKC_PKCa_PRKCB_ST	Q03721	KCNC4	P05771	PRKCB	T49	T56P	56	Missense	distal	7	no	4.661	4.728	EPSD	ICGC;COSMIC	0.942	Up-regulation
AGC_PKC_PKCa_PRKCB_ST	Q03721	KCNC4	P05771	PRKCB	T49	L54M	54	Missense	distal	5	no	4.661	4.679	EPSD	ICGC;COSMIC	0.942	Up-regulation
AGC_PKC_PKCa_PRKCB_ST	Q03721	KCNC4	P05771	PRKCB	S514	R516W	516	Missense	proximal	2	no	3.036	-6.478	EPSD	ICGC;COSMIC	0.942	Loss
AGC_PKC_PKCa_PRKCB_ST	Q03721	KCNC4	P05771	PRKCB	S514	C520Y	520	Missense	distal	6	no	3.036	3.156	EPSD	ICGC;COSMIC	0.942	Up-regulation
AGC_PKC_PKCa_PRKCB_ST	Q03721	KCNC4	P05771	PRKCB	S514	R516Q	516	Missense	proximal	2	no	3.036	-3.513	EPSD	ICGC;COSMIC	0.942	Loss
AGC_PKC_PKCa_PRKCB_ST	Q03721	KCNC4	P05771	PRKCB	S514	P515L	515	Missense	proximal	1	no	3.036	4.172	EPSD	ICGC;COSMIC	0.942	Up-regulation
AGC_PKC_PKCa_PRKCB_ST	Q03721	KCNC4	P05771	PRKCB	S514	S518I	518	Missense	distal	4	no	3.036	3.177	EPSD	ICGC	0.942	Up-regulation
AGC_PKC_PKCa_PRKCB_ST	Q03721	KCNC4	P05771	PRKCB	T578	R576H	576	Missense	proximal	-2	no	7.188	5.173	EPSD	ICGC;COSMIC	0.942	Down-regulation
AGC_PKC_PKCa_PRKCB_ST	P15336	ATF2	P05771	PRKCB	S314	S321G	321	Missense	distal	7	no	1.491	1.621	EPSD	ICGC;COSMIC	0.942	Up-regulation
AGC_PKC_PKCa_PRKCB_ST	P15336	ATF2	P05771	PRKCB	S340	S340L	340	Missense	central	0	yes	2.871	0.000	EPSD	ICGC;COSMIC	0.942	Loss
AGC_PKC_PKCa_PRKCB_ST	P15336	ATF2	P05771	PRKCB	S340	Q337H	337	Missense	distal	-3	no	2.871	3.083	EPSD	ICGC;COSMIC	0.942	Up-regulation
AGC_PKC_PKCa_PRKCB_ST	P15336	ATF2	P05771	PRKCB	S367	A365V	365	Missense	proximal	-2	no	0.774	0.986	EPSD	ICGC;COSMIC	0.942	Gain
AGC_PKC_PKCa_PRKCB_ST	Q06124	PTPN11	P05771	PRKCB	S28	A31S	31	Missense	distal	3	no	0.909	1.122	EPSD	ICGC	0.942	Gain
AGC_PKC_PKCa_PRKCB_ST	Q06124	PTPN11	P05771	PRKCB	S34	A31S	31	Missense	distal	-3	no	0.684	1.215	EPSD	ICGC	0.942	Gain
AGC_PKC_PKCa_PRKCB_ST	Q06124	PTPN11	P05771	PRKCB	S140	P144H	144	Missense	distal	4	no	1.121	1.182	EPSD	ICGC;COSMIC	0.942	Up-regulation
AGC_PKC_PKCa_PRKCB_ST	Q06124	PTPN11	P05771	PRKCB	S140	E139D	139	Missense	proximal	-1	no	1.121	1.035	EPSD	ICGC;COSMIC	0.942	Down-regulation
AGC_PKC_PKCa_PRKCB_ST	Q06124	PTPN11	P05771	PRKCB	S160	G158W	158	Missense	proximal	-2	no	0.985	-0.424	EPSD	ICGC	0.942	Loss
AGC_PKC_PKCa_PRKCB_ST	Q06124	PTPN11	P05771	PRKCB	S160	D155Y	155	Missense	distal	-5	no	0.985	0.982	EPSD	ICGC;COSMIC	0.942	Down-regulation
AGC_PKC_PKCa_PRKCB_ST	P49841	GSK3B	P05771	PRKCB	S9	A11S	11	Missense	proximal	2	no	2.332	4.335	PhosphoSitePlus	ICGC;COSMIC	0.942	Up-regulation
AGC_PKC_PKCa_PRKCB_ST	P49841	GSK3B	P05771	PRKCB	S13	A11S	11	Missense	proximal	-2	no	1.665	1.504	EPSD	ICGC;COSMIC	0.942	Down-regulation
AGC_PKC_PKCa_PRKCB_ST	P49841	GSK3B	P05771	PRKCB	S35	D33E	33	Missense	proximal	-2	no	2.853	3.766	EPSD	ICGC	0.942	Up-regulation
AGC_PKC_PKCa_PRKCB_ST	P49841	GSK3B	P05771	PRKCB	S55	Q52K	52	Missense	distal	-3	no	-1.443	1.986	EPSD	ICGC	0.942	Gain
AGC_PKC_PKCa_PRKCB_ST	P49841	GSK3B	P05771	PRKCB	S147	A149D	149	Missense	proximal	2	no	0.378	1.733	EPSD	ICGC	0.942	Gain
AGC_PKC_PKCa_PRKCB_ST	P49841	GSK3B	P05771	PRKCB	S147	Q151R	151	Missense	distal	4	no	0.378	0.998	EPSD	ICGC;COSMIC	0.942	Gain
AGC_PKC_PKCa_PRKCB_ST	P49841	GSK3B	P05771	PRKCB	T275	L273R	273	Missense	proximal	-2	no	-1.561	0.959	EPSD	ICGC	0.942	Gain
AGC_PKC_PKCa_PRKCB_ST	P07355	ANXA2	P05771	PRKCB	S26	T19A	19	Missense	distal	-7	no	2.460	2.488	PhosphoSitePlus	ICGC;COSMIC	0.942	Up-regulation
AGC_PKC_PKCa_PRKCB_ST	P07355	ANXA2	P05771	PRKCB	S26	Y30C	30	Missense	distal	4	no	2.460	1.923	PhosphoSitePlus	ICGC;COSMIC	0.942	Down-regulation
AGC_PKC_PKCa_PRKCB_ST	P07355	ANXA2	P05771	PRKCB	S26	P21T	21	Missense	distal	-5	no	2.460	2.536	PhosphoSitePlus	ICGC;COSMIC	0.942	Up-regulation
AGC_PKC_PKCa_PRKCB_ST	P07355	ANXA2	P05771	PRKCB	S234	S236N	236	Missense	proximal	2	no	2.916	3.635	EPSD	ICGC;COSMIC	0.942	Up-regulation
AGC_PKC_PKCa_PRKCB_ST	P07355	ANXA2	P05771	PRKCB	S234	D230H	230	Missense	distal	-4	no	2.916	2.907	EPSD	ICGC;COSMIC	0.942	Down-regulation
AGC_PKC_PKCa_PRKCB_ST	P07355	ANXA2	P05771	PRKCB	S234	P237H	237	Missense	distal	3	no	2.916	2.809	EPSD	ICGC;COSMIC	0.942	Down-regulation
AGC_PKC_PKCa_PRKCB_ST	P07355	ANXA2	P05771	PRKCB	S234	R231M	231	Missense	distal	-3	no	2.916	-0.086	EPSD	ICGC;COSMIC	0.942	Loss
AGC_PKC_PKCa_PRKCB_ST	P07355	ANXA2	P05771	PRKCB	S234	M240T	240	Missense	distal	6	no	2.916	3.081	EPSD	ICGC;COSMIC	0.942	Up-regulation
AGC_PKC_PKCa_PRKCB_ST	P07355	ANXA2	P05771	PRKCB	S243	S236N	236	Missense	distal	-7	no	3.897	3.884	EPSD	ICGC;COSMIC	0.942	Down-regulation
AGC_PKC_PKCa_PRKCB_ST	P07355	ANXA2	P05771	PRKCB	S243	R245S	245	Missense	proximal	2	no	3.897	-2.100	EPSD	ICGC	0.942	Loss
AGC_PKC_PKCa_PRKCB_ST	P07355	ANXA2	P05771	PRKCB	S243	P237H	237	Missense	distal	-6	no	3.897	3.979	EPSD	ICGC;COSMIC	0.942	Up-regulation
AGC_PKC_PKCa_PRKCB_ST	P07355	ANXA2	P05771	PRKCB	S243	M240T	240	Missense	distal	-3	no	3.897	4.418	EPSD	ICGC;COSMIC	0.942	Up-regulation
AGC_PKC_PKCa_PRKCB_ST	P07355	ANXA2	P05771	PRKCB	S277	R273W	273	Missense	distal	-4	no	1.315	1.894	EPSD	ICGC;COSMIC	0.942	Up-regulation
AGC_PKC_PKCa_PRKCB_ST	P07355	ANXA2	P05771	PRKCB	S277	R284Q	284	Missense	distal	7	no	1.315	1.391	EPSD	ICGC;COSMIC	0.942	Up-regulation
AGC_PKC_PKCa_PRKCB_ST	P07355	ANXA2	P05771	PRKCB	S277	G280D	280	Missense	distal	3	no	1.315	1.685	EPSD	ICGC	0.942	Up-regulation
AGC_PKC_PKCa_PRKCB_ST	Q96D31	ORAI1	P05771	PRKCB	S25	S30I	30	Missense	distal	5	no	2.117	2.204	EPSD	ICGC	0.942	Up-regulation
AGC_PKC_PKCa_PRKCB_ST	Q96D31	ORAI1	P05771	PRKCB	S27	S30I	30	Missense	distal	3	no	8.853	8.646	PhosphoSitePlus;EPSD	ICGC	0.942	Down-regulation
AGC_PKC_PKCa_PRKCB_ST	Q96D31	ORAI1	P05771	PRKCB	S30	S30I	30	Missense	central	0	yes	8.414	0.000	EPSD;PhosphoSitePlus	ICGC	0.942	Loss
AGC_PKC_PKCa_PRKCB_ST	Q96D31	ORAI1	P05771	PRKCB	S34	S30I	30	Missense	distal	-4	no	3.160	3.131	EPSD	ICGC	0.942	Down-regulation
AGC_PKC_PKCa_PRKCB_ST	Q96D31	ORAI1	P05771	PRKCB	S34	G37W	37	Missense	distal	3	no	3.160	2.836	EPSD	ICGC	0.942	Down-regulation
AGC_PKC_PKCa_PRKCB_ST	Q16625	OCLN	P05771	PRKCB	S2	L6F	6	Missense	distal	4	no	3.990	4.129	EPSD	ICGC	0.942	Up-regulation
AGC_PKC_PKCa_PRKCB_ST	Q9UBS0	RPS6KB2	P05771	PRKCB	T228	V225I	225	Missense	distal	-3	no	1.590	0.611	EPSD	ICGC;COSMIC	0.942	Loss
AGC_PKC_PKCa_PRKCB_ST	Q9UBS0	RPS6KB2	P05771	PRKCB	T228	I233T	233	Missense	distal	5	no	1.590	1.570	EPSD	ICGC;COSMIC	0.942	Down-regulation
AGC_PKC_PKCa_PRKCB_ST	Q9UBS0	RPS6KB2	P05771	PRKCB	S410	F404L	404	Missense	distal	-6	no	7.610	7.617	EPSD	ICGC	0.942	Up-regulation
AGC_PKC_PKCa_PRKCB_ST	Q9UBS0	RPS6KB2	P05771	PRKCB	S417	V422I	422	Missense	distal	5	no	1.767	1.861	EPSD	ICGC;COSMIC;CCLE	0.942	Up-regulation
AGC_PKC_PKCa_PRKCB_ST	Q9UBS0	RPS6KB2	P05771	PRKCB	S417	A420V	420	Missense	distal	3	no	1.767	1.612	EPSD	ICGC;COSMIC	0.942	Down-regulation
AGC_PKC_PKCa_PRKCB_ST	Q9UBS0	RPS6KB2	P05771	PRKCB	S436	S438N	438	Missense	proximal	2	no	0.912	1.631	EPSD	ICGC;COSMIC	0.942	Gain
AGC_PKC_PKCa_PRKCB_ST	P35548	MSX2	P05771	PRKCB	S44	P46T	46	Missense	proximal	2	no	1.972	3.161	EPSD	ICGC;COSMIC	0.942	Up-regulation
AGC_PKC_PKCa_PRKCB_ST	P35548	MSX2	P05771	PRKCB	T141	C134F	134	Missense	distal	-7	no	4.647	4.775	PhosphoSitePlus;EPSD	ICGC	0.942	Up-regulation
AGC_PKC_PKCa_PRKCB_ST	P35548	MSX2	P05771	PRKCB	T141	R137K	137	Missense	distal	-4	no	4.647	4.592	PhosphoSitePlus;EPSD	ICGC;COSMIC	0.942	Down-regulation
AGC_PKC_PKCa_PRKCB_ST	O15519	CFLAR	P05771	PRKCB	S193	A189S	189	Missense	distal	-4	no	3.351	3.295	PhosphoSitePlus	ICGC;COSMIC	0.942	Down-regulation
AGC_PKC_PKCa_PRKCB_ST	O15519	CFLAR	P05771	PRKCB	S193	I190V	190	Missense	distal	-3	no	3.351	4.331	PhosphoSitePlus	ICGC;COSMIC	0.942	Up-regulation
AGC_PKC_PKCa_PRKCB_ST	P48736	PIK3CG	P05771	PRKCB	S227	H225Q	225	Missense	proximal	-2	no	1.324	2.367	EPSD	ICGC;COSMIC	0.942	Up-regulation
AGC_PKC_PKCa_PRKCB_ST	P48736	PIK3CG	P05771	PRKCB	S227	K234R	234	Missense	distal	7	no	1.324	1.213	EPSD	ICGC;COSMIC	0.942	Down-regulation
AGC_PKC_PKCa_PRKCB_ST	P48736	PIK3CG	P05771	PRKCB	S417	S417I	417	Missense	central	0	yes	3.333	0.000	EPSD	ICGC;COSMIC	0.942	Loss
AGC_PKC_PKCa_PRKCB_ST	P48736	PIK3CG	P05771	PRKCB	T607	Q609R	609	Missense	proximal	2	no	-2.078	4.471	EPSD	ICGC;COSMIC	0.942	Gain
AGC_PKC_PKCa_PRKCB_ST	P21730	C5AR1	P05771	PRKCB	S327	S327F	327	Missense	central	0	yes	1.648	0.000	EPSD	ICGC	0.942	Loss
AGC_PKC_PKCa_PRKCB_ST	P21730	C5AR1	P05771	PRKCB	S327	L323F	323	Missense	distal	-4	no	1.648	1.567	EPSD	ICGC;COSMIC	0.942	Down-regulation
AGC_PKC_PKCa_PRKCB_ST	P21730	C5AR1	P05771	PRKCB	S332	R337C	337	Missense	distal	5	no	1.111	0.667	EPSD	ICGC;COSMIC;CCLE	0.942	Loss
AGC_PKC_PKCa_PRKCB_ST	P21730	C5AR1	P05771	PRKCB	S332	S327F	327	Missense	distal	-5	no	1.111	1.139	EPSD	ICGC	0.942	Up-regulation
AGC_PKC_PKCa_PRKCB_ST	P21730	C5AR1	P05771	PRKCB	S334	R337C	337	Missense	distal	3	no	0.990	0.137	PhosphoSitePlus	ICGC;COSMIC;CCLE	0.942	Loss
AGC_PKC_PKCa_PRKCB_ST	P21730	C5AR1	P05771	PRKCB	S334	S327F	327	Missense	distal	-7	no	0.990	1.062	PhosphoSitePlus	ICGC	0.942	Up-regulation
AGC_PKC_PKCa_PRKCB_ST	P31749	AKT1	P05771	PRKCB	S246	A250D	250	Missense	distal	4	no	0.465	1.011	EPSD	ICGC	0.942	Gain
AGC_PKC_PKCa_PRKCB_ST	P31749	AKT1	P05771	PRKCB	T308	T305N	305	Missense	distal	-3	no	1.425	0.976	EPSD;PhosphoSitePlus	ICGC	0.942	Down-regulation
AGC_PKC_PKCa_PRKCB_ST	P31749	AKT1	P05771	PRKCB	S422	K420T	420	Missense	proximal	-2	no	2.176	0.679	EPSD	ICGC	0.942	Loss
AGC_PKC_PKCa_PRKCB_ST	P31749	AKT1	P05771	PRKCB	S473	Q471K	471	Missense	proximal	-2	no	-0.062	1.019	PhosphoSitePlus;EPSD	ICGC	0.942	Gain
AGC_PKC_PKCa_PRKCB_ST	P31749	AKT1	P05771	PRKCB	S473	S477R	477	Missense	distal	4	no	-0.062	0.955	PhosphoSitePlus;EPSD	ICGC	0.942	Gain
AGC_PKC_PKCa_PRKCB_ST	P31749	AKT1	P05771	PRKCB	S475	S477R	477	Missense	proximal	2	no	-1.472	4.525	EPSD	ICGC	0.942	Gain
AGC_PKC_PKCa_PRKCB_ST	Q9P2D0	IBTK	P05771	PRKCB	S695	K701R	701	Missense	distal	6	no	2.838	2.687	EPSD	ICGC;COSMIC	0.942	Down-regulation
AGC_PKC_PKCa_PRKCB_ST	Q9P2D0	IBTK	P05771	PRKCB	S765	V770M	770	Missense	distal	5	no	2.408	2.383	EPSD	ICGC;COSMIC	0.942	Down-regulation
AGC_PKC_PKCa_PRKCB_ST	Q9P2D0	IBTK	P05771	PRKCB	T872	A876D	876	Missense	distal	4	no	0.706	1.252	EPSD	ICGC	0.942	Gain
AGC_PKC_PKCa_PRKCB_ST	Q9P2D0	IBTK	P05771	PRKCB	S1154	Q1155R	1155	Missense	proximal	1	no	9.095	9.793	EPSD	ICGC	0.942	Up-regulation
AGC_PKC_PKCa_PRKCB_ST	Q9P2D0	IBTK	P05771	PRKCB	S1203	E1210K	1210	Missense	distal	7	no	2.615	2.594	EPSD;PhosphoSitePlus	ICGC	0.942	Down-regulation
AGC_PKC_PKCa_PRKCB_ST	Q9UH77	KLHL3	P05771	PRKCB	S9	Q11K	11	Missense	proximal	2	no	0.278	5.203	EPSD	ICGC;COSMIC	0.942	Gain
AGC_PKC_PKCa_PRKCB_ST	Q9UH77	KLHL3	P05771	PRKCB	S10	S5I	5	Missense	distal	-5	no	2.790	2.865	EPSD	ICGC;COSMIC	0.942	Up-regulation
AGC_PKC_PKCa_PRKCB_ST	Q9UH77	KLHL3	P05771	PRKCB	S10	S9T	9	Missense	proximal	-1	no	2.790	2.974	EPSD	ICGC;COSMIC	0.942	Up-regulation
AGC_PKC_PKCa_PRKCB_ST	Q9UH77	KLHL3	P05771	PRKCB	S10	G17W	17	Missense	distal	7	no	2.790	2.791	EPSD	ICGC;COSMIC;CCLE	0.942	Up-regulation
AGC_PKC_PKCa_PRKCB_ST	Q9UH77	KLHL3	P05771	PRKCB	S10	Q11K	11	Missense	proximal	1	no	2.790	3.602	EPSD	ICGC;COSMIC	0.942	Up-regulation
AGC_PKC_PKCa_PRKCB_ST	P35568	IRS1	P05771	PRKCB	S24	K23N	23	Missense	proximal	-1	no	1.120	0.837	EPSD	ICGC;COSMIC	0.942	Loss
AGC_PKC_PKCa_PRKCB_ST	P35568	IRS1	P05771	PRKCB	S268	R265H	265	Missense	distal	-3	no	3.296	0.310	EPSD	ICGC	0.942	Loss
AGC_PKC_PKCa_PRKCB_ST	P35568	IRS1	P05771	PRKCB	S268	F264L	264	Missense	distal	-4	no	3.296	3.377	EPSD	ICGC	0.942	Up-regulation
AGC_PKC_PKCa_PRKCB_ST	P35568	IRS1	P05771	PRKCB	S268	S272P	272	Missense	distal	4	no	3.296	3.431	EPSD	ICGC	0.942	Up-regulation
AGC_PKC_PKCa_PRKCB_ST	P35568	IRS1	P05771	PRKCB	S268	S268I	268	Missense	central	0	yes	3.296	0.000	EPSD	ICGC;COSMIC	0.942	Loss
AGC_PKC_PKCa_PRKCB_ST	P35568	IRS1	P05771	PRKCB	S272	R265H	265	Missense	distal	-7	no	1.748	2.074	EPSD	ICGC	0.942	Up-regulation
AGC_PKC_PKCa_PRKCB_ST	P35568	IRS1	P05771	PRKCB	S272	S272P	272	Missense	central	0	yes	1.748	0.000	EPSD	ICGC	0.942	Loss
AGC_PKC_PKCa_PRKCB_ST	P35568	IRS1	P05771	PRKCB	S272	N278T	278	Missense	distal	6	no	1.748	1.456	EPSD	ICGC	0.942	Down-regulation
AGC_PKC_PKCa_PRKCB_ST	P35568	IRS1	P05771	PRKCB	S272	S268I	268	Missense	distal	-4	no	1.748	1.720	EPSD	ICGC;COSMIC	0.942	Down-regulation
AGC_PKC_PKCa_PRKCB_ST	P35568	IRS1	P05771	PRKCB	S273	S272P	272	Missense	proximal	-1	no	1.684	1.625	EPSD	ICGC	0.942	Down-regulation
AGC_PKC_PKCa_PRKCB_ST	P35568	IRS1	P05771	PRKCB	S273	N278T	278	Missense	distal	5	no	1.684	1.656	EPSD	ICGC	0.942	Down-regulation
AGC_PKC_PKCa_PRKCB_ST	P35568	IRS1	P05771	PRKCB	S273	S268I	268	Missense	distal	-5	no	1.684	1.759	EPSD	ICGC;COSMIC	0.942	Up-regulation
AGC_PKC_PKCa_PRKCB_ST	P35568	IRS1	P05771	PRKCB	S303	T300P	300	Missense	distal	-3	no	4.483	3.751	EPSD	ICGC;COSMIC;GDSC	0.942	Down-regulation
AGC_PKC_PKCa_PRKCB_ST	P35568	IRS1	P05771	PRKCB	S303	V297G	297	Missense	distal	-6	no	4.483	4.355	EPSD	ICGC;COSMIC	0.942	Down-regulation
AGC_PKC_PKCa_PRKCB_ST	P35568	IRS1	P05771	PRKCB	S307	T300P	300	Missense	distal	-7	no	4.780	4.964	EPSD	ICGC;COSMIC;GDSC	0.942	Up-regulation
AGC_PKC_PKCa_PRKCB_ST	P35568	IRS1	P05771	PRKCB	S323	G319R	319	Missense	distal	-4	no	8.318	7.901	PhosphoSitePlus;EPSD	ICGC;COSMIC	0.942	Down-regulation
AGC_PKC_PKCa_PRKCB_ST	P35568	IRS1	P05771	PRKCB	S330	G332S	332	Missense	proximal	2	no	-0.706	2.031	EPSD	ICGC;COSMIC	0.942	Gain
AGC_PKC_PKCa_PRKCB_ST	P35568	IRS1	P05771	PRKCB	S341	S345N	345	Missense	distal	4	no	0.741	1.069	EPSD	ICGC	0.942	Gain
AGC_PKC_PKCa_PRKCB_ST	P35568	IRS1	P05771	PRKCB	T351	H355Q	355	Missense	distal	4	no	2.051	2.253	EPSD	ICGC	0.942	Up-regulation
AGC_PKC_PKCa_PRKCB_ST	P35568	IRS1	P05771	PRKCB	T351	S345N	345	Missense	distal	-6	no	2.051	2.148	EPSD	ICGC	0.942	Up-regulation
AGC_PKC_PKCa_PRKCB_ST	P35568	IRS1	P05771	PRKCB	S362	H355Q	355	Missense	distal	-7	no	4.417	4.117	EPSD	ICGC	0.942	Down-regulation
AGC_PKC_PKCa_PRKCB_ST	P35568	IRS1	P05771	PRKCB	S362	L369H	369	Missense	distal	7	no	4.417	4.413	EPSD	ICGC;COSMIC	0.942	Down-regulation
AGC_PKC_PKCa_PRKCB_ST	P35568	IRS1	P05771	PRKCB	S391	S393T	393	Missense	proximal	2	no	0.055	1.409	EPSD	ICGC;COSMIC	0.942	Gain
AGC_PKC_PKCa_PRKCB_ST	P35568	IRS1	P05771	PRKCB	S413	S412P	412	Missense	proximal	-1	no	1.222	1.163	EPSD	ICGC	0.942	Down-regulation
AGC_PKC_PKCa_PRKCB_ST	P35568	IRS1	P05771	PRKCB	S413	A414D	414	Missense	proximal	1	no	1.222	0.932	EPSD	ICGC	0.942	Loss
AGC_PKC_PKCa_PRKCB_ST	P35568	IRS1	P05771	PRKCB	S413	R411L	411	Missense	proximal	-2	no	1.222	-1.298	EPSD	ICGC;COSMIC	0.942	Loss
AGC_PKC_PKCa_PRKCB_ST	P35568	IRS1	P05771	PRKCB	S413	R410W	410	Missense	distal	-3	no	1.222	-4.271	EPSD	ICGC	0.942	Loss
AGC_PKC_PKCa_PRKCB_ST	P35568	IRS1	P05771	PRKCB	S419	S421R	421	Missense	proximal	2	no	-3.709	2.288	EPSD	ICGC	0.942	Gain
AGC_PKC_PKCa_PRKCB_ST	P35568	IRS1	P05771	PRKCB	S441	D437Y	437	Missense	distal	-4	no	7.878	7.759	EPSD;PhosphoSitePlus	ICGC;COSMIC	0.942	Down-regulation
AGC_PKC_PKCa_PRKCB_ST	P35568	IRS1	P05771	PRKCB	S581	P578H	578	Missense	distal	-3	no	1.534	1.760	EPSD	ICGC	0.942	Up-regulation
AGC_PKC_PKCa_PRKCB_ST	P35568	IRS1	P05771	PRKCB	S581	A575T	575	Missense	distal	-6	no	1.534	1.675	EPSD	ICGC;COSMIC	0.942	Up-regulation
AGC_PKC_PKCa_PRKCB_ST	P35568	IRS1	P05771	PRKCB	S603	R600H	600	Missense	distal	-3	no	2.483	-0.504	EPSD	ICGC;COSMIC	0.942	Loss
AGC_PKC_PKCa_PRKCB_ST	P35568	IRS1	P05771	PRKCB	S624	K627N	627	Missense	distal	3	no	2.446	2.299	EPSD	ICGC;COSMIC	0.942	Down-regulation
AGC_PKC_PKCa_PRKCB_ST	P35568	IRS1	P05771	PRKCB	S636	P634S	634	Missense	proximal	-2	no	1.075	0.954	EPSD	ICGC;COSMIC	0.942	Down-regulation
AGC_PKC_PKCa_PRKCB_ST	P35568	IRS1	P05771	PRKCB	S636	Y632C	632	Missense	distal	-4	no	1.075	1.385	EPSD	ICGC;COSMIC	0.942	Up-regulation
AGC_PKC_PKCa_PRKCB_ST	P35568	IRS1	P05771	PRKCB	S795	T793A	793	Missense	proximal	-2	no	3.003	2.597	EPSD	ICGC;COSMIC	0.942	Down-regulation
AGC_PKC_PKCa_PRKCB_ST	P35568	IRS1	P05771	PRKCB	S795	Y800C	800	Missense	distal	5	no	3.003	2.873	EPSD	ICGC;COSMIC	0.942	Down-regulation
AGC_PKC_PKCa_PRKCB_ST	P35568	IRS1	P05771	PRKCB	S795	T793S	793	Missense	proximal	-2	no	3.003	2.437	EPSD	ICGC;COSMIC	0.942	Down-regulation
AGC_PKC_PKCa_PRKCB_ST	P35568	IRS1	P05771	PRKCB	S795	R790H	790	Missense	distal	-5	no	3.003	2.755	EPSD	ICGC	0.942	Down-regulation
AGC_PKC_PKCa_PRKCB_ST	P35568	IRS1	P05771	PRKCB	S974	G971R	971	Missense	distal	-3	no	-0.693	3.522	EPSD	ICGC;COSMIC	0.942	Gain
AGC_PKC_PKCa_PRKCB_ST	P35568	IRS1	P05771	PRKCB	S1101	S1106L	1106	Missense	distal	5	no	1.721	1.671	EPSD	ICGC;COSMIC	0.942	Down-regulation
AGC_PKC_PKCa_PRKCB_ST	P35568	IRS1	P05771	PRKCB	S1142	D1137N	1137	Missense	distal	-5	no	4.666	4.600	EPSD	ICGC	0.942	Down-regulation
AGC_PKC_PKCa_PRKCB_ST	P35568	IRS1	P05771	PRKCB	S1143	D1137N	1137	Missense	distal	-6	no	1.236	1.302	EPSD	ICGC	0.942	Up-regulation
AGC_PKC_PKCa_PRKCB_ST	P35568	IRS1	P05771	PRKCB	S1218	L1211R	1211	Missense	distal	-7	no	2.552	2.287	EPSD	ICGC;COSMIC	0.942	Down-regulation
AGC_PKC_PKCa_PRKCB_ST	P35568	IRS1	P05771	PRKCB	S1218	R1220H	1220	Missense	proximal	2	no	2.552	-3.810	EPSD	ICGC;COSMIC	0.942	Loss
AGC_PKC_PKCa_PRKCB_ST	P35568	IRS1	P05771	PRKCB	S1218	T1219P	1219	Missense	proximal	1	no	2.552	2.591	EPSD	ICGC;COSMIC;GDSC	0.942	Up-regulation
AGC_PKC_PKCa_PRKCB_ST	P35568	IRS1	P05771	PRKCB	T1219	R1220H	1220	Missense	proximal	1	no	3.984	2.277	EPSD	ICGC;COSMIC	0.942	Down-regulation
AGC_PKC_PKCa_PRKCB_ST	P35568	IRS1	P05771	PRKCB	T1219	T1219P	1219	Missense	central	0	yes	3.984	0.000	EPSD	ICGC;COSMIC;GDSC	0.942	Loss
AGC_PKC_PKCa_PRKCB_ST	Q13131	PRKAA1	P05771	PRKCB	S5	W7L	7	Missense	proximal	2	no	-0.378	2.504	EPSD	ICGC;COSMIC	0.942	Gain
AGC_PKC_PKCa_PRKCB_ST	Q13131	PRKAA1	P05771	PRKCB	S6	W7L	7	Missense	proximal	1	no	4.131	6.120	EPSD	ICGC;COSMIC	0.942	Up-regulation
AGC_PKC_PKCa_PRKCB_ST	Q13131	PRKAA1	P05771	PRKCB	S6	R2C	2	Missense	distal	-4	no	4.131	4.637	EPSD	ICGC;COSMIC	0.942	Up-regulation
AGC_PKC_PKCa_PRKCB_ST	Q13131	PRKAA1	P05771	PRKCB	T382	R386H	386	Missense	distal	4	no	3.070	2.248	EPSD	ICGC;COSMIC	0.942	Down-regulation
AGC_PKC_PKCa_PRKCB_ST	Q13131	PRKAA1	P05771	PRKCB	T382	R386C	386	Missense	distal	4	no	3.070	1.932	EPSD	ICGC;COSMIC	0.942	Down-regulation
AGC_PKC_PKCa_PRKCB_ST	Q13131	PRKAA1	P05771	PRKCB	T382	L389I	389	Missense	distal	7	no	3.070	3.010	EPSD	ICGC;COSMIC	0.942	Down-regulation
AGC_PKC_PKCa_PRKCB_ST	Q13131	PRKAA1	P05771	PRKCB	T382	R384M	384	Missense	proximal	2	no	3.070	-3.691	EPSD	ICGC;COSMIC	0.942	Loss
AGC_PKC_PKCa_PRKCB_ST	Q13131	PRKAA1	P05771	PRKCB	S467	Q464K	464	Missense	distal	-3	no	-0.396	3.033	EPSD	ICGC;COSMIC	0.942	Gain
AGC_PKC_PKCa_PRKCB_ST	Q13131	PRKAA1	P05771	PRKCB	S496	S498C	498	Missense	proximal	2	no	1.295	2.799	PhosphoSitePlus	ICGC;COSMIC	0.942	Up-regulation
AGC_PKC_PKCa_PRKCB_ST	Q13131	PRKAA1	P05771	PRKCB	S496	R501P	501	Missense	distal	5	no	1.295	0.831	PhosphoSitePlus	ICGC;COSMIC	0.942	Loss
AGC_PKC_PKCa_PRKCB_ST	Q13131	PRKAA1	P05771	PRKCB	S496	C503Y	503	Missense	distal	7	no	1.295	1.212	PhosphoSitePlus	ICGC	0.942	Down-regulation
AGC_PKC_PKCa_PRKCB_ST	Q13131	PRKAA1	P05771	PRKCB	S496	Y500C	500	Missense	distal	4	no	1.295	0.759	PhosphoSitePlus	ICGC;COSMIC	0.942	Loss
AGC_PKC_PKCa_PRKCB_ST	Q13131	PRKAA1	P05771	PRKCB	S541	T543K	543	Missense	proximal	2	no	0.467	3.487	EPSD	ICGC;COSMIC	0.942	Gain
AGC_PKC_PKCa_PRKCB_ST	P11171	EPB41	P05771	PRKCB	S14	E12K	12	Missense	proximal	-2	no	0.063	1.507	EPSD	ICGC	0.942	Gain
AGC_PKC_PKCa_PRKCB_ST	P11171	EPB41	P05771	PRKCB	S104	E110K	110	Missense	distal	6	no	2.786	3.283	EPSD	ICGC;COSMIC	0.942	Up-regulation
AGC_PKC_PKCa_PRKCB_ST	P11171	EPB41	P05771	PRKCB	S180	I182K	182	Missense	proximal	2	no	1.126	4.785	EPSD	ICGC;COSMIC	0.942	Up-regulation
AGC_PKC_PKCa_PRKCB_ST	P11171	EPB41	P05771	PRKCB	S188	S191T	191	Missense	distal	3	no	1.715	1.894	EPSD	ICGC;COSMIC	0.942	Up-regulation
AGC_PKC_PKCa_PRKCB_ST	P11171	EPB41	P05771	PRKCB	S188	I182K	182	Missense	distal	-6	no	1.715	2.034	EPSD	ICGC;COSMIC	0.942	Up-regulation
AGC_PKC_PKCa_PRKCB_ST	P11171	EPB41	P05771	PRKCB	S188	A193P	193	Missense	distal	5	no	1.715	1.529	EPSD	ICGC;COSMIC	0.942	Down-regulation
AGC_PKC_PKCa_PRKCB_ST	P11171	EPB41	P05771	PRKCB	S200	A193P	193	Missense	distal	-7	no	4.920	5.075	EPSD	ICGC;COSMIC	0.942	Up-regulation
AGC_PKC_PKCa_PRKCB_ST	P11171	EPB41	P05771	PRKCB	S441	R444L	444	Missense	distal	3	no	2.927	1.842	EPSD	ICGC	0.942	Down-regulation
AGC_PKC_PKCa_PRKCB_ST	P11171	EPB41	P05771	PRKCB	S446	R444L	444	Missense	proximal	-2	no	4.381	1.861	EPSD	ICGC	0.942	Down-regulation
AGC_PKC_PKCa_PRKCB_ST	P11171	EPB41	P05771	PRKCB	S446	P453S	453	Missense	distal	7	no	4.381	4.288	EPSD	ICGC	0.942	Down-regulation
AGC_PKC_PKCa_PRKCB_ST	P11171	EPB41	P05771	PRKCB	S469	R471P	471	Missense	proximal	2	no	6.823	0.991	EPSD	ICGC	0.942	Down-regulation
AGC_PKC_PKCa_PRKCB_ST	P11171	EPB41	P05771	PRKCB	S469	L476I	476	Missense	distal	7	no	6.823	6.763	EPSD	ICGC;COSMIC	0.942	Down-regulation
AGC_PKC_PKCa_PRKCB_ST	P11171	EPB41	P05771	PRKCB	S469	T462I	462	Missense	distal	-7	no	6.823	6.719	EPSD	ICGC;COSMIC	0.942	Down-regulation
AGC_PKC_PKCa_PRKCB_ST	P11171	EPB41	P05771	PRKCB	S521	S521N	521	Missense	central	0	yes	1.966	0.000	EPSD	ICGC;COSMIC	0.942	Loss
AGC_PKC_PKCa_PRKCB_ST	P11171	EPB41	P05771	PRKCB	S521	S521I	521	Missense	central	0	yes	1.966	0.000	EPSD	ICGC;COSMIC	0.942	Loss
AGC_PKC_PKCa_PRKCB_ST	P11171	EPB41	P05771	PRKCB	S521	A522S	522	Missense	proximal	1	no	1.966	1.356	EPSD	ICGC	0.942	Down-regulation
AGC_PKC_PKCa_PRKCB_ST	P11171	EPB41	P05771	PRKCB	S521	A528T	528	Missense	distal	7	no	1.966	1.875	EPSD	ICGC;COSMIC	0.942	Down-regulation
AGC_PKC_PKCa_PRKCB_ST	P11171	EPB41	P05771	PRKCB	S536	R538Q	538	Missense	proximal	2	no	9.014	2.465	EPSD	ICGC;COSMIC	0.942	Down-regulation
AGC_PKC_PKCa_PRKCB_ST	P11171	EPB41	P05771	PRKCB	S536	S536N	536	Missense	central	0	yes	9.014	0.000	EPSD	ICGC	0.942	Loss
AGC_PKC_PKCa_PRKCB_ST	P11171	EPB41	P05771	PRKCB	S536	A539S	539	Missense	distal	3	no	9.014	9.228	EPSD	ICGC;COSMIC	0.942	Up-regulation
AGC_PKC_PKCa_PRKCB_ST	P11171	EPB41	P05771	PRKCB	S540	R538Q	538	Missense	proximal	-2	no	3.582	2.611	EPSD	ICGC;COSMIC	0.942	Down-regulation
AGC_PKC_PKCa_PRKCB_ST	P11171	EPB41	P05771	PRKCB	S540	S536N	536	Missense	distal	-4	no	3.582	3.565	EPSD	ICGC	0.942	Down-regulation
AGC_PKC_PKCa_PRKCB_ST	P11171	EPB41	P05771	PRKCB	S540	D544N	544	Missense	distal	4	no	3.582	3.835	EPSD	ICGC;COSMIC	0.942	Up-regulation
AGC_PKC_PKCa_PRKCB_ST	P11171	EPB41	P05771	PRKCB	S540	A539S	539	Missense	proximal	-1	no	3.582	3.554	EPSD	ICGC;COSMIC	0.942	Down-regulation
AGC_PKC_PKCa_PRKCB_ST	P11171	EPB41	P05771	PRKCB	S560	A563S	563	Missense	distal	3	no	1.167	1.381	EPSD	ICGC	0.942	Up-regulation
AGC_PKC_PKCa_PRKCB_ST	P11171	EPB41	P05771	PRKCB	T736	Q735H	735	Missense	proximal	-1	no	1.884	1.587	EPSD	ICGC	0.942	Down-regulation
AGC_PKC_PKCa_PRKCB_ST	P16949	STMN1	P05771	PRKCB	S25	L24F	24	Missense	proximal	-1	no	1.193	1.351	PhosphoSitePlus;EPSD	ICGC;COSMIC	0.942	Up-regulation
AGC_PKC_PKCa_PRKCB_ST	P16949	STMN1	P05771	PRKCB	S25	E30K	30	Missense	distal	5	no	1.193	1.363	PhosphoSitePlus;EPSD	ICGC	0.942	Up-regulation
AGC_PKC_PKCa_PRKCB_ST	P16949	STMN1	P05771	PRKCB	S25	E30Q	30	Missense	distal	5	no	1.193	1.324	PhosphoSitePlus;EPSD	ICGC;COSMIC	0.942	Up-regulation
AGC_PKC_PKCa_PRKCB_ST	P16949	STMN1	P05771	PRKCB	S25	S31P	31	Missense	distal	6	no	1.193	1.606	PhosphoSitePlus;EPSD	ICGC;COSMIC	0.942	Up-regulation
AGC_PKC_PKCa_PRKCB_ST	P16949	STMN1	P05771	PRKCB	S28	E30K	30	Missense	proximal	2	no	-0.631	4.783	EPSD	ICGC	0.942	Gain
AGC_PKC_PKCa_PRKCB_ST	P16949	STMN1	P05771	PRKCB	S31	L24F	24	Missense	distal	-7	no	0.894	0.973	EPSD	ICGC;COSMIC	0.942	Gain
AGC_PKC_PKCa_PRKCB_ST	P16949	STMN1	P05771	PRKCB	S31	E30K	30	Missense	proximal	-1	no	0.894	1.038	EPSD	ICGC	0.942	Gain
AGC_PKC_PKCa_PRKCB_ST	P16949	STMN1	P05771	PRKCB	S31	E30Q	30	Missense	proximal	-1	no	0.894	1.029	EPSD	ICGC;COSMIC	0.942	Gain
AGC_PKC_PKCa_PRKCB_ST	P16949	STMN1	P05771	PRKCB	S63	S63F	63	Missense	central	0	yes	0.957	0.000	EPSD	ICGC;COSMIC	0.942	Loss
AGC_PKC_PKCa_PRKCB_ST	P16949	STMN1	P05771	PRKCB	T102	A97E	97	Missense	distal	-5	no	0.984	1.079	EPSD	ICGC	0.942	Up-regulation
AGC_PKC_PKCa_PRKCB_ST	P16949	STMN1	P05771	PRKCB	T102	H103N	103	Missense	proximal	1	no	0.984	-0.015	EPSD	ICGC	0.942	Loss
AGC_PKC_PKCa_PRKCB_ST	P14679	TYR	P05771	PRKCB	S339	L344M	344	Missense	distal	5	no	6.771	6.789	EPSD	ICGC	0.942	Up-regulation
AGC_PKC_PKCa_PRKCB_ST	P14679	TYR	P05771	PRKCB	S339	D333Y	333	Missense	distal	-6	no	6.771	6.759	EPSD	ICGC;COSMIC	0.942	Down-regulation
AGC_PKC_PKCa_PRKCB_ST	P28329	CHAT	P05771	PRKCB	S594	L597F	597	Missense	distal	3	no	2.132	2.190	EPSD	ICGC;COSMIC	0.942	Up-regulation
AGC_PKC_PKCa_PRKCB_ST	P28329	CHAT	P05771	PRKCB	S594	A590T	590	Missense	distal	-4	no	2.132	2.027	EPSD	ICGC;COSMIC	0.942	Down-regulation
AGC_PKC_PKCa_PRKCB_ST	Q12906	ILF3	P05771	PRKCB	S19	R12L	12	Missense	distal	-7	no	1.596	1.860	EPSD	ICGC;COSMIC	0.942	Up-regulation
AGC_PKC_PKCa_PRKCB_ST	Q12906	ILF3	P05771	PRKCB	S19	R12S	12	Missense	distal	-7	no	1.596	1.867	EPSD	ICGC;COSMIC	0.942	Up-regulation
AGC_PKC_PKCa_PRKCB_ST	Q12906	ILF3	P05771	PRKCB	S19	A16T	16	Missense	distal	-3	no	1.596	3.042	EPSD	ICGC;COSMIC	0.942	Up-regulation
AGC_PKC_PKCa_PRKCB_ST	Q12906	ILF3	P05771	PRKCB	S20	A16T	16	Missense	distal	-4	no	2.945	2.840	EPSD	ICGC;COSMIC	0.942	Down-regulation
AGC_PKC_PKCa_PRKCB_ST	Q12906	ILF3	P05771	PRKCB	S209	W215C	215	Missense	distal	6	no	0.500	0.960	EPSD	ICGC	0.942	Gain
AGC_PKC_PKCa_PRKCB_ST	Q12906	ILF3	P05771	PRKCB	S382	K388N	388	Missense	distal	6	no	2.280	1.651	EPSD	ICGC;COSMIC	0.942	Down-regulation
AGC_PKC_PKCa_PRKCB_ST	Q12906	ILF3	P05771	PRKCB	S382	K389N	389	Missense	distal	7	no	2.280	2.322	EPSD	ICGC	0.942	Up-regulation
AGC_PKC_PKCa_PRKCB_ST	Q12906	ILF3	P05771	PRKCB	S384	K388N	388	Missense	distal	4	no	5.050	4.475	EPSD	ICGC;COSMIC	0.942	Down-regulation
AGC_PKC_PKCa_PRKCB_ST	Q12906	ILF3	P05771	PRKCB	S384	K389N	389	Missense	distal	5	no	5.050	4.677	EPSD	ICGC	0.942	Down-regulation
AGC_PKC_PKCa_PRKCB_ST	Q12906	ILF3	P05771	PRKCB	S476	G473V	473	Missense	distal	-3	no	-1.008	0.993	EPSD	ICGC	0.942	Gain
AGC_PKC_PKCa_PRKCB_ST	Q12906	ILF3	P05771	PRKCB	T547	G549R	549	Missense	proximal	2	no	-5.902	2.832	EPSD	ICGC;COSMIC	0.942	Gain
AGC_PKC_PKCa_PRKCB_ST	Q12906	ILF3	P05771	PRKCB	S647	R640Q	640	Missense	distal	-7	no	10.233	10.258	PhosphoSitePlus	ICGC;COSMIC	0.942	Up-regulation
AGC_PKC_PKCa_PRKCB_ST	Q12906	ILF3	P05771	PRKCB	S647	G646V	646	Missense	proximal	-1	no	10.233	10.295	PhosphoSitePlus	ICGC;COSMIC	0.942	Up-regulation
AGC_PKC_PKCa_PRKCB_ST	Q12906	ILF3	P05771	PRKCB	S647	R651Q	651	Missense	distal	4	no	10.233	9.614	PhosphoSitePlus	ICGC;COSMIC	0.942	Down-regulation
AGC_PKC_PKCa_PRKCB_ST	P30273	FCER1G	P05771	PRKCB	S69	T75I	75	Missense	distal	6	no	6.023	5.660	PhosphoSitePlus	ICGC;COSMIC	0.942	Down-regulation
AGC_PKC_PKCa_PRKCB_ST	P30273	FCER1G	P05771	PRKCB	S69	N72K	72	Missense	distal	3	no	6.023	6.170	PhosphoSitePlus	ICGC;COSMIC	0.942	Up-regulation
AGC_PKC_PKCa_PRKCB_ST	P30273	FCER1G	P05771	PRKCB	S69	V64F	64	Missense	distal	-5	no	6.023	6.039	PhosphoSitePlus	ICGC	0.942	Up-regulation
AGC_PKC_PKCa_PRKCB_ST	P30273	FCER1G	P05771	PRKCB	S69	E74A	74	Missense	distal	5	no	6.023	5.853	PhosphoSitePlus	ICGC;COSMIC	0.942	Down-regulation
AGC_PKC_PKCa_PRKCB_ST	P30273	FCER1G	P05771	PRKCB	S69	N72Y	72	Missense	distal	3	no	6.023	5.847	PhosphoSitePlus	ICGC;COSMIC	0.942	Down-regulation
AGC_PKC_PKCa_PRKCB_ST	P49840	GSK3A	P05771	PRKCB	S97	G98R	98	Missense	proximal	1	no	0.435	2.545	EPSD	ICGC	0.942	Gain
AGC_PKC_PKCa_PRKCB_ST	P49840	GSK3A	P05771	PRKCB	S266	L259P	259	Missense	distal	-7	no	2.948	3.079	EPSD	ICGC;COSMIC	0.942	Up-regulation
CAMK_CAMKL_PASK_PASK_ST	Q96RG2	PASK	Q96RG2	PASK	S17	Q18K	18	Missense	proximal	1	no	2.030	2.078	EPSD	ICGC;COSMIC	1.643	Up-regulation
CAMK_CAMKL_PASK_PASK_ST	Q96RG2	PASK	Q96RG2	PASK	S70	C73F	73	Missense	distal	3	no	1.929	1.625	EPSD	ICGC;COSMIC	1.643	Loss
CAMK_CAMKL_PASK_PASK_ST	Q96RG2	PASK	Q96RG2	PASK	S70	S70R	70	Missense	central	0	yes	1.929	0.000	EPSD	ICGC;COSMIC	1.643	Loss
CAMK_CAMKL_PASK_PASK_ST	Q96RG2	PASK	Q96RG2	PASK	T512	P506H	506	Missense	distal	-6	no	2.316	2.291	EPSD	ICGC;COSMIC	1.643	Down-regulation
CAMK_CAMKL_PASK_PASK_ST	Q96RG2	PASK	Q96RG2	PASK	T512	L514S	514	Missense	proximal	2	no	2.316	2.154	EPSD	ICGC;COSMIC	1.643	Down-regulation
CAMK_CAMKL_PASK_PASK_ST	Q96RG2	PASK	Q96RG2	PASK	T512	Q510K	510	Missense	proximal	-2	no	2.316	2.105	EPSD	ICGC	1.643	Down-regulation
CAMK_CAMKL_PASK_PASK_ST	Q96RG2	PASK	Q96RG2	PASK	T850	P844Q	844	Missense	distal	-6	no	2.078	2.037	EPSD	ICGC;COSMIC	1.643	Down-regulation
CAMK_CAMKL_PASK_PASK_ST	Q96RG2	PASK	Q96RG2	PASK	T1161	T1161N	1161	Missense	central	0	yes	4.170	0.000	EPSD;PhosphoSitePlus	ICGC;COSMIC	1.643	Loss
CAMK_CAMKL_PASK_PASK_ST	Q96RG2	PASK	Q96RG2	PASK	T1161	E1167K	1167	Missense	distal	6	no	4.170	4.174	EPSD;PhosphoSitePlus	ICGC;COSMIC	1.643	Up-regulation
CAMK_CAMKL_PASK_PASK_ST	Q96RG2	PASK	Q96RG2	PASK	T1161	K1157N	1157	Missense	distal	-4	no	4.170	3.920	EPSD;PhosphoSitePlus	ICGC;COSMIC	1.643	Down-regulation
CAMK_CAMKL_PASK_PASK_ST	Q96RG2	PASK	Q96RG2	PASK	T1165	T1161N	1161	Missense	distal	-4	no	4.135	4.223	PhosphoSitePlus;EPSD	ICGC;COSMIC	1.643	Up-regulation
CAMK_CAMKL_PASK_PASK_ST	Q96RG2	PASK	Q96RG2	PASK	T1165	E1167K	1167	Missense	proximal	2	no	4.135	3.983	PhosphoSitePlus;EPSD	ICGC;COSMIC	1.643	Down-regulation
CAMK_CAMKL_PASK_PASK_ST	Q96RG2	PASK	Q96RG2	PASK	T1322	P1318T	1318	Missense	distal	-4	no	1.540	1.708	EPSD	ICGC	1.643	Gain
CAMK_CAMKL_PASK_PASK_ST	P68104	EEF1A1	Q96RG2	PASK	T82	I75T	75	Missense	distal	-7	no	1.838	1.784	EPSD	ICGC;COSMIC	1.643	Down-regulation
CAMK_CAMKL_PASK_PASK_ST	P68104	EEF1A1	Q96RG2	PASK	T82	K79T	79	Missense	distal	-3	no	1.838	1.625	EPSD	ICGC	1.643	Loss
CAMK_CAMKL_PASK_PASK_ST	P68104	EEF1A1	Q96RG2	PASK	S83	K79T	79	Missense	distal	-4	no	1.859	1.520	EPSD	ICGC	1.643	Loss
CAMK_CAMKL_PASK_PASK_ST	P68104	EEF1A1	Q96RG2	PASK	T106	A112T	112	Missense	distal	6	no	1.600	1.672	EPSD	ICGC;COSMIC	1.643	Gain
CAMK_CAMKL_PASK_PASK_ST	P68104	EEF1A1	Q96RG2	PASK	T432	R427H	427	Missense	distal	-5	no	4.305	4.160	PhosphoSitePlus	ICGC;COSMIC	1.643	Down-regulation
CAMK_CAMKL_PASK_PASK_ST	P68104	EEF1A1	Q96RG2	PASK	T432	T432A	432	Missense	central	0	yes	4.305	0.000	PhosphoSitePlus	ICGC;COSMIC	1.643	Loss
Other_TOPK_PBK_ST	P05412	JUN	Q96KB5	PBK	S63	K70T	70	Missense	distal	7	no	6.536	6.526	EPSD;PhosphoSitePlus	ICGC;COSMIC	2.342	Down-regulation
Other_TOPK_PBK_ST	P05412	JUN	Q96KB5	PBK	S73	A72E	72	Missense	proximal	-1	no	5.452	5.402	PhosphoSitePlus;EPSD	ICGC;COSMIC	2.342	Down-regulation
Other_TOPK_PBK_ST	P05412	JUN	Q96KB5	PBK	S73	K70T	70	Missense	distal	-3	no	5.452	5.299	PhosphoSitePlus;EPSD	ICGC;COSMIC	2.342	Down-regulation
Other_TOPK_PBK_ST	P81274	GPSM2	Q96KB5	PBK	S468	D472Y	472	Missense	distal	4	no	3.673	3.629	EPSD	ICGC;COSMIC	2.342	Down-regulation
Other_TOPK_PBK_ST	P81274	GPSM2	Q96KB5	PBK	S468	A467S	467	Missense	proximal	-1	no	3.673	3.625	EPSD	ICGC;COSMIC	2.342	Down-regulation
Other_TOPK_PBK_ST	P81274	GPSM2	Q96KB5	PBK	S468	R474Q	474	Missense	distal	6	no	3.673	3.663	EPSD	ICGC;COSMIC	2.342	Down-regulation
Other_TOPK_PBK_ST	P81274	GPSM2	Q96KB5	PBK	S567	R573H	573	Missense	distal	6	no	2.571	2.583	EPSD	ICGC;COSMIC	2.342	Up-regulation
Other_TOPK_PBK_ST	Q06830	PRDX1	Q96KB5	PBK	S32	L31M	31	Missense	proximal	-1	no	5.543	5.569	PhosphoSitePlus	ICGC	2.342	Up-regulation
Other_TOPK_PBK_ST	Q06830	PRDX1	Q96KB5	PBK	S106	R110H	110	Missense	distal	4	no	2.591	2.651	EPSD	ICGC	2.342	Up-regulation
Other_TOPK_PBK_ST	Q06830	PRDX1	Q96KB5	PBK	S152	R151S	151	Missense	proximal	-1	no	2.860	2.867	EPSD	ICGC;COSMIC	2.342	Up-regulation
TKL_RAF_RAF_BRAF_ST	P19634	SLC9A1	P15056	BRAF	T653	R647Q	647	Missense	distal	-6	no	4.142	3.794	PhosphoSitePlus	ICGC;COSMIC;CCLE	2.269	Down-regulation
TKL_RAF_RAF_BRAF_ST	P19634	SLC9A1	P15056	BRAF	T653	Y649H	649	Missense	distal	-4	no	4.142	4.330	PhosphoSitePlus	ICGC;COSMIC	2.269	Up-regulation
TKL_RAF_RAF_BRAF_ST	Q92934	BAD	P15056	BRAF	S75	R72S	72	Missense	distal	-3	no	4.371	4.348	PhosphoSitePlus;EPSD	ICGC	2.269	Down-regulation
TKL_RAF_RAF_BRAF_ST	Q92934	BAD	P15056	BRAF	S75	T80K	80	Missense	distal	5	no	4.371	3.949	PhosphoSitePlus;EPSD	ICGC	2.269	Down-regulation
TKL_RAF_RAF_BRAF_ST	Q92934	BAD	P15056	BRAF	S75	S74G	74	Missense	proximal	-1	no	4.371	4.297	PhosphoSitePlus;EPSD	ICGC;COSMIC	2.269	Down-regulation
TKL_RAF_RAF_BRAF_ST	Q92934	BAD	P15056	BRAF	T80	T80K	80	Missense	central	0	yes	2.363	0.000	EPSD	ICGC	2.269	Loss
TKL_RAF_RAF_BRAF_ST	Q92934	BAD	P15056	BRAF	T80	S74G	74	Missense	distal	-6	no	2.363	2.505	EPSD	ICGC;COSMIC	2.269	Up-regulation
TKL_RAF_RAF_BRAF_ST	Q92934	BAD	P15056	BRAF	S99	S99L	99	Missense	central	0	yes	4.087	0.000	EPSD;PhosphoSitePlus	ICGC	2.269	Loss
TKL_RAF_RAF_BRAF_ST	Q92934	BAD	P15056	BRAF	S99	R94W	94	Missense	distal	-5	no	4.087	4.022	EPSD;PhosphoSitePlus	ICGC	2.269	Down-regulation
TKL_RAF_RAF_BRAF_ST	Q92934	BAD	P15056	BRAF	S118	R112S	112	Missense	distal	-6	no	4.381	4.083	EPSD;PhosphoSitePlus	ICGC	2.269	Down-regulation
TKL_RAF_RAF_BRAF_ST	Q92934	BAD	P15056	BRAF	S145	R149L	149	Missense	distal	4	no	2.564	2.555	EPSD	ICGC;COSMIC	2.269	Down-regulation
TKL_RAF_RAF_BRAF_ST	P68104	EEF1A1	P15056	BRAF	S21	G19V	19	Missense	proximal	-2	no	4.317	4.205	EPSD;PhosphoSitePlus	ICGC	2.269	Down-regulation
TKL_RAF_RAF_BRAF_ST	P68104	EEF1A1	P15056	BRAF	S21	K20N	20	Missense	proximal	-1	no	4.317	4.435	EPSD;PhosphoSitePlus	ICGC	2.269	Up-regulation
TKL_RAF_RAF_BRAF_ST	P68104	EEF1A1	P15056	BRAF	S21	H26L	26	Missense	distal	5	no	4.317	4.227	EPSD;PhosphoSitePlus	ICGC	2.269	Down-regulation
TKL_RAF_RAF_BRAF_ST	P68104	EEF1A1	P15056	BRAF	T88	D91Y	91	Missense	distal	3	no	3.164	3.135	PhosphoSitePlus;EPSD	ICGC;COSMIC	2.269	Down-regulation
TKL_RAF_RAF_BRAF_ST	Q9H9S0	NANOG	P15056	BRAF	S57	D59N	59	Missense	proximal	2	no	2.653	2.639	EPSD	ICGC;COSMIC	2.269	Down-regulation
TKL_RAF_RAF_BRAF_ST	P15056	BRAF	P15056	BRAF	T244	R239Q	239	Missense	distal	-5	no	2.425	2.433	EPSD	ICGC;COSMIC	2.269	Up-regulation
TKL_RAF_RAF_BRAF_ST	P15056	BRAF	P15056	BRAF	T244	D249Y	249	Missense	distal	5	no	2.425	2.310	EPSD	ICGC;COSMIC	2.269	Down-regulation
TKL_RAF_RAF_BRAF_ST	P15056	BRAF	P15056	BRAF	T313	S316P	316	Missense	distal	3	no	2.210	2.358	EPSD	ICGC;COSMIC	2.269	Gain
TKL_RAF_RAF_BRAF_ST	P15056	BRAF	P15056	BRAF	S335	P334L	334	Missense	proximal	-1	no	2.230	2.305	EPSD	ICGC;COSMIC	2.269	Gain
TKL_RAF_RAF_BRAF_ST	P15056	BRAF	P15056	BRAF	T373	N372K	372	Missense	proximal	-1	no	3.959	3.841	EPSD;PhosphoSitePlus	ICGC	2.269	Down-regulation
TKL_RAF_RAF_BRAF_ST	P15056	BRAF	P15056	BRAF	T373	P367L	367	Missense	distal	-6	no	3.959	3.853	EPSD;PhosphoSitePlus	ICGC;COSMIC	2.269	Down-regulation
TKL_RAF_RAF_BRAF_ST	P15056	BRAF	P15056	BRAF	T401	A404D	404	Missense	distal	3	no	2.275	2.210	EPSD	ICGC;COSMIC	2.269	Loss
TKL_RAF_RAF_BRAF_ST	P15056	BRAF	P15056	BRAF	T401	S394T	394	Missense	distal	-7	no	2.275	2.241	EPSD	ICGC;COSMIC	2.269	Loss
TKL_RAF_RAF_BRAF_ST	P15056	BRAF	P15056	BRAF	S409	A404D	404	Missense	distal	-5	no	2.381	2.365	EPSD	ICGC;COSMIC	2.269	Down-regulation
TKL_RAF_RAF_BRAF_ST	P15056	BRAF	P15056	BRAF	S409	L410Q	410	Missense	proximal	1	no	2.381	2.355	EPSD	ICGC	2.269	Down-regulation
TKL_RAF_RAF_BRAF_ST	P15056	BRAF	P15056	BRAF	S428	S429Y	429	Missense	proximal	1	no	2.410	2.424	EPSD	ICGC	2.269	Up-regulation
TKL_RAF_RAF_BRAF_ST	P15056	BRAF	P15056	BRAF	S428	Q423H	423	Missense	distal	-5	no	2.410	2.356	EPSD	ICGC;COSMIC	2.269	Down-regulation
TKL_RAF_RAF_BRAF_ST	P15056	BRAF	P15056	BRAF	T440	R444Q	444	Missense	distal	4	no	2.323	2.351	EPSD	ICGC;COSMIC	2.269	Up-regulation
TKL_RAF_RAF_BRAF_ST	P15056	BRAF	P15056	BRAF	T440	R444W	444	Missense	distal	4	no	2.323	2.303	EPSD	ICGC;COSMIC	2.269	Down-regulation
TKL_RAF_RAF_BRAF_ST	P15056	BRAF	P15056	BRAF	T440	T440K	440	Missense	central	0	yes	2.323	0.000	EPSD	ICGC	2.269	Loss
TKL_RAF_RAF_BRAF_ST	P15056	BRAF	P15056	BRAF	T440	L441I	441	Missense	proximal	1	no	2.323	2.319	EPSD	ICGC;COSMIC	2.269	Down-regulation
TKL_RAF_RAF_BRAF_ST	P15056	BRAF	P15056	BRAF	T440	S446L	446	Missense	distal	6	no	2.323	2.360	EPSD	ICGC;COSMIC	2.269	Up-regulation
TKL_RAF_RAF_BRAF_ST	P15056	BRAF	P15056	BRAF	T440	M438I	438	Missense	proximal	-2	no	2.323	2.466	EPSD	ICGC;COSMIC	2.269	Up-regulation
TKL_RAF_RAF_BRAF_ST	P15056	BRAF	P15056	BRAF	S446	E451D	451	Missense	distal	5	no	2.213	2.321	EPSD	ICGC;COSMIC	2.269	Gain
TKL_RAF_RAF_BRAF_ST	Q02750	MAP2K1	P15056	BRAF	S212	L215I	215	Missense	distal	3	no	2.283	2.255	EPSD	ICGC;COSMIC	2.269	Loss
TKL_RAF_RAF_BRAF_ST	Q02750	MAP2K1	P15056	BRAF	S218	G225C	225	Missense	distal	7	no	4.261	4.245	EPSD;PhosphoSitePlus	ICGC	2.269	Down-regulation
TKL_RAF_RAF_BRAF_ST	Q02750	MAP2K1	P15056	BRAF	S218	L215I	215	Missense	distal	-3	no	4.261	3.979	EPSD;PhosphoSitePlus	ICGC;COSMIC	2.269	Down-regulation
TKL_RAF_RAF_BRAF_ST	Q02750	MAP2K1	P15056	BRAF	S222	G225C	225	Missense	distal	3	no	4.478	4.563	PhosphoSitePlus;EPSD	ICGC	2.269	Up-regulation
TKL_RAF_RAF_BRAF_ST	Q02750	MAP2K1	P15056	BRAF	S222	L215I	215	Missense	distal	-7	no	4.478	4.465	PhosphoSitePlus;EPSD	ICGC;COSMIC	2.269	Down-regulation
TKL_RAF_RAF_BRAF_ST	Q05639	EEF1A2	P15056	BRAF	S21	S21F	21	Missense	central	0	yes	4.317	0.000	PhosphoSitePlus	ICGC	2.269	Loss
TKL_RAF_RAF_BRAF_ST	Q05639	EEF1A2	P15056	BRAF	S21	V16M	16	Missense	distal	-5	no	4.317	4.347	PhosphoSitePlus	ICGC;COSMIC	2.269	Up-regulation
TKL_RAF_RAF_BRAF_ST	Q05639	EEF1A2	P15056	BRAF	S163	P160Q	160	Missense	distal	-3	no	2.194	2.422	EPSD	ICGC	2.269	Gain
TKL_RAF_RAF_BRAF_ST	Q05639	EEF1A2	P15056	BRAF	S224	G225R	225	Missense	proximal	1	no	2.268	2.280	EPSD	ICGC	2.269	Gain
TKL_RAF_RAF_BRAF_ST	P33981	TTK	P15056	BRAF	T51	S49A	49	Missense	proximal	-2	no	2.107	2.444	EPSD	ICGC;COSMIC	2.269	Gain
TKL_RAF_RAF_BRAF_ST	P33981	TTK	P15056	BRAF	S281	D283N	283	Missense	proximal	2	no	4.020	4.005	PhosphoSitePlus;EPSD	ICGC	2.269	Down-regulation
TKL_RAF_RAF_BRAF_ST	P33981	TTK	P15056	BRAF	S837	G838S	838	Missense	proximal	1	no	2.494	2.479	EPSD	ICGC;COSMIC	2.269	Down-regulation
TKL_RAF_RAF_BRAF_ST	P36507	MAP2K2	P15056	BRAF	S226	R231C	231	Missense	distal	5	no	4.058	4.060	PhosphoSitePlus;EPSD	ICGC;COSMIC	2.269	Up-regulation
TKL_RAF_RAF_BRAF_ST	P36507	MAP2K2	P15056	BRAF	S372	F368I	368	Missense	distal	-4	no	2.121	2.371	EPSD	ICGC;COSMIC	2.269	Gain
Other_NEK_NEK9_NEK9_ST	Q8NHV4	NEDD1	Q8TD19	NEK9	S325	R324Q	324	Missense	proximal	-1	no	2.588	3.120	EPSD	ICGC;COSMIC;CCLE	2.671	Gain
Other_NEK_NEK9_NEK9_ST	Q8NHV4	NEDD1	Q8TD19	NEK9	S377	T380R	380	Missense	distal	3	no	7.648	7.643	PhosphoSitePlus	ICGC;COSMIC	2.671	Down-regulation
Other_NEK_NEK9_NEK9_ST	Q8NHV4	NEDD1	Q8TD19	NEK9	S377	R376Q	376	Missense	proximal	-1	no	7.648	8.180	PhosphoSitePlus	ICGC;COSMIC	2.671	Up-regulation
Other_NEK_NEK9_NEK9_ST	Q8NHV4	NEDD1	Q8TD19	NEK9	S377	K371I	371	Missense	distal	-6	no	7.648	6.815	PhosphoSitePlus	ICGC;COSMIC	2.671	Down-regulation
Other_NEK_NEK9_NEK9_ST	Q8NHV4	NEDD1	Q8TD19	NEK9	T382	T380R	380	Missense	proximal	-2	no	2.637	2.675	EPSD	ICGC;COSMIC	2.671	Gain
Other_NEK_NEK9_NEK9_ST	Q8NHV4	NEDD1	Q8TD19	NEK9	T382	R376Q	376	Missense	distal	-6	no	2.637	3.382	EPSD	ICGC;COSMIC	2.671	Gain
Other_NEK_NEK9_NEK9_ST	Q8NHV4	NEDD1	Q8TD19	NEK9	T382	E386K	386	Missense	distal	4	no	2.637	2.758	EPSD	ICGC;COSMIC	2.671	Gain
Other_NEK_NEK9_NEK9_ST	Q8NHV4	NEDD1	Q8TD19	NEK9	S389	G390V	390	Missense	proximal	1	no	2.274	2.866	EPSD	ICGC	2.671	Gain
Other_NEK_NEK9_NEK9_ST	Q8NHV4	NEDD1	Q8TD19	NEK9	S404	D400N	400	Missense	distal	-4	no	3.442	3.329	EPSD	ICGC;COSMIC	2.671	Down-regulation
Other_NEK_NEK9_NEK9_ST	Q8NHV4	NEDD1	Q8TD19	NEK9	S404	S404G	404	Missense	central	0	yes	3.442	0.000	EPSD	ICGC;COSMIC	2.671	Loss
Other_NEK_NEK9_NEK9_ST	Q8NHV4	NEDD1	Q8TD19	NEK9	S404	M409I	409	Missense	distal	5	no	3.442	3.033	EPSD	ICGC	2.671	Down-regulation
Other_NEK_NEK9_NEK9_ST	Q8NHV4	NEDD1	Q8TD19	NEK9	S404	D399Y	399	Missense	distal	-5	no	3.442	3.445	EPSD	ICGC	2.671	Up-regulation
Other_NEK_NEK9_NEK9_ST	Q8NHV4	NEDD1	Q8TD19	NEK9	S404	G402V	402	Missense	proximal	-2	no	3.442	3.432	EPSD	ICGC;COSMIC	2.671	Down-regulation
Other_NEK_NEK9_NEK9_ST	Q8NHV4	NEDD1	Q8TD19	NEK9	S404	G407C	407	Missense	distal	3	no	3.442	3.444	EPSD	ICGC;COSMIC	2.671	Up-regulation
Other_NEK_NEK9_NEK9_ST	Q8NHV4	NEDD1	Q8TD19	NEK9	S404	F410L	410	Missense	distal	6	no	3.442	3.448	EPSD	ICGC;COSMIC	2.671	Up-regulation
Other_NEK_NEK9_NEK9_ST	Q8NHV4	NEDD1	Q8TD19	NEK9	S455	P461S	461	Missense	distal	6	no	3.005	2.984	EPSD	ICGC	2.671	Down-regulation
Other_NEK_NEK9_NEK9_ST	Q8NHV4	NEDD1	Q8TD19	NEK9	S518	S525A	525	Missense	distal	7	no	2.774	2.717	EPSD	ICGC;COSMIC	2.671	Down-regulation
Other_NEK_NEK9_NEK9_ST	Q8NHV4	NEDD1	Q8TD19	NEK9	S518	S525Y	525	Missense	distal	7	no	2.774	2.747	EPSD	ICGC;COSMIC	2.671	Down-regulation
Other_NEK_NEK9_NEK9_ST	Q8NHV4	NEDD1	Q8TD19	NEK9	S548	G547E	547	Missense	proximal	-1	no	2.090	2.677	EPSD	ICGC	2.671	Gain
Other_NEK_NEK9_NEK9_ST	Q8NHV4	NEDD1	Q8TD19	NEK9	S549	I545V	545	Missense	distal	-4	no	2.980	2.961	EPSD	ICGC;COSMIC	2.671	Down-regulation
Other_NEK_NEK9_NEK9_ST	Q8NHV4	NEDD1	Q8TD19	NEK9	S549	P553Q	553	Missense	distal	4	no	2.980	2.888	EPSD	ICGC;COSMIC	2.671	Down-regulation
Other_NEK_NEK9_NEK9_ST	Q8NHV4	NEDD1	Q8TD19	NEK9	S549	G547E	547	Missense	proximal	-2	no	2.980	3.007	EPSD	ICGC	2.671	Up-regulation
Other_NEK_NEK9_NEK9_ST	Q8NHV4	NEDD1	Q8TD19	NEK9	S566	S568L	568	Missense	proximal	2	no	3.031	3.096	EPSD	ICGC;COSMIC	2.671	Up-regulation
Other_NEK_NEK9_NEK9_ST	Q8NHV4	NEDD1	Q8TD19	NEK9	S566	A561S	561	Missense	distal	-5	no	3.031	3.096	EPSD	ICGC	2.671	Up-regulation
Other_NEK_NEK9_NEK9_ST	Q8NHV4	NEDD1	Q8TD19	NEK9	S566	S566L	566	Missense	central	0	yes	3.031	0.000	EPSD	ICGC;COSMIC	2.671	Loss
Other_NEK_NEK9_NEK9_ST	Q8NHV4	NEDD1	Q8TD19	NEK9	S566	G562V	562	Missense	distal	-4	no	3.031	2.990	EPSD	ICGC;COSMIC	2.671	Down-regulation
Other_NEK_NEK9_NEK9_ST	Q8TDX7	NEK7	Q8TD19	NEK9	S195	A193S	193	Missense	proximal	-2	no	8.327	8.235	PhosphoSitePlus	ICGC	2.671	Down-regulation
Other_NEK_NEK9_NEK9_ST	Q8TDX7	NEK7	Q8TD19	NEK9	S195	T199R	199	Missense	distal	4	no	8.327	7.836	PhosphoSitePlus	ICGC;COSMIC	2.671	Down-regulation
Other_NEK_NEK9_NEK9_ST	Q8TD19	NEK9	Q8TD19	NEK9	S76	R70H	70	Missense	distal	-6	no	3.201	3.636	EPSD	ICGC	2.671	Up-regulation
Other_NEK_NEK9_NEK9_ST	Q8TD19	NEK9	Q8TD19	NEK9	S206	A208D	208	Missense	proximal	2	no	2.959	2.969	EPSD	ICGC;COSMIC	2.671	Up-regulation
Other_NEK_NEK9_NEK9_ST	Q8TD19	NEK9	Q8TD19	NEK9	T210	A208D	208	Missense	proximal	-2	no	7.795	7.564	EPSD;PhosphoSitePlus	ICGC;COSMIC	2.671	Down-regulation
Other_NEK_NEK9_NEK9_ST	Q8TD19	NEK9	Q8TD19	NEK9	T335	A340D	340	Missense	distal	5	no	2.194	2.794	EPSD	ICGC	2.671	Gain
Other_NEK_NEK9_NEK9_ST	Q8TD19	NEK9	Q8TD19	NEK9	S836	L843M	843	Missense	distal	7	no	3.338	3.380	EPSD	ICGC	2.671	Up-regulation
Other_NEK_NEK9_NEK9_ST	Q8TD19	NEK9	Q8TD19	NEK9	S836	K840E	840	Missense	distal	4	no	3.338	3.217	EPSD	ICGC	2.671	Down-regulation
Other_NEK_NEK9_NEK9_ST	Q8TD19	NEK9	Q8TD19	NEK9	S836	S829F	829	Missense	distal	-7	no	3.338	3.364	EPSD	ICGC	2.671	Up-regulation
Other_NEK_NEK9_NEK9_ST	Q8TD19	NEK9	Q8TD19	NEK9	S869	P874T	874	Missense	distal	5	no	2.774	2.489	EPSD	ICGC	2.671	Loss
Other_NEK_NEK9_NEK9_ST	Q8TD19	NEK9	Q8TD19	NEK9	S869	K862T	862	Missense	distal	-7	no	2.774	2.784	EPSD	ICGC	2.671	Up-regulation
Other_NEK_NEK9_NEK9_ST	Q8TD19	NEK9	Q8TD19	NEK9	S944	M942I	942	Missense	proximal	-2	no	8.113	8.054	PhosphoSitePlus;EPSD	ICGC;COSMIC	2.671	Down-regulation
Other_NEK_NEK9_NEK9_ST	Q8TD19	NEK9	Q8TD19	NEK9	T949	M942I	942	Missense	distal	-7	no	2.783	2.772	EPSD	ICGC;COSMIC	2.671	Down-regulation
Other_NEK_NEK9_NEK9_ST	Q8TD19	NEK9	Q8TD19	NEK9	T949	E955K	955	Missense	distal	6	no	2.783	2.766	EPSD	ICGC;COSMIC	2.671	Down-regulation
Other_NEK_NEK9_NEK9_ST	Q8TD19	NEK9	Q8TD19	NEK9	S964	K959N	959	Missense	distal	-5	no	2.755	2.737	EPSD	ICGC	2.671	Down-regulation
Other_NEK_NEK9_NEK9_ST	Q8TD19	NEK9	Q8TD19	NEK9	S966	K959N	959	Missense	distal	-7	no	3.066	3.056	EPSD	ICGC	2.671	Down-regulation
Other_NEK_NEK9_NEK9_ST	Q8TD19	NEK9	Q8TD19	NEK9	S978	P977F	977	Missense	proximal	-1	no	3.393	2.750	EPSD	ICGC	2.671	Down-regulation
Other_NEK_NEK9_NEK9_ST	Q9HC98	NEK6	Q8TD19	NEK9	T35	R39L	39	Missense	distal	4	no	3.825	3.686	EPSD	ICGC;COSMIC	2.671	Down-regulation
Other_NEK_NEK9_NEK9_ST	Q9HC98	NEK6	Q8TD19	NEK9	T35	C40R	40	Missense	distal	5	no	3.825	3.697	EPSD	ICGC;COSMIC	2.671	Down-regulation
Other_NEK_NEK9_NEK9_ST	Q9HC98	NEK6	Q8TD19	NEK9	T35	R39H	39	Missense	distal	4	no	3.825	3.963	EPSD	ICGC	2.671	Up-regulation
Other_NEK_NEK9_NEK9_ST	Q9HC98	NEK6	Q8TD19	NEK9	S165	A159T	159	Missense	distal	-6	no	1.798	3.011	EPSD	ICGC	2.671	Gain
CAMK_MLCK_MYLK_ST	O14950	MYL12B	Q15746	MYLK	T19	T19A	19	Missense	central	0	yes	1.827	0.000	EPSD;PhosphoSitePlus	ICGC;COSMIC	1.165	Loss
CAMK_MLCK_MYLK_ST	O14950	MYL12B	Q15746	MYLK	S20	T19A	19	Missense	proximal	-1	no	1.417	1.432	PhosphoSitePlus;EPSD	ICGC;COSMIC	1.165	Up-regulation
CAMK_MLCK_MYLK_ST	O14950	MYL12B	Q15746	MYLK	T160	R161C	161	Missense	proximal	1	no	1.182	1.191	EPSD	ICGC;COSMIC	1.165	Up-regulation
CAMK_MLCK_MYLK_ST	O14950	MYL12B	Q15746	MYLK	T160	R161L	161	Missense	proximal	1	no	1.182	1.196	EPSD	ICGC	1.165	Up-regulation
CAMK_MLCK_MYLK_ST	P10916	MYL2	Q15746	MYLK	S15	A10D	10	Missense	distal	-5	no	1.569	1.434	PhosphoSitePlus	ICGC;COSMIC	1.165	Down-regulation
CAMK_MLCK_MYLK_ST	P10916	MYL2	Q15746	MYLK	T98	A102V	102	Missense	distal	4	no	1.295	1.537	EPSD	ICGC;COSMIC	1.165	Up-regulation
CAMK_MLCK_MYLK_ST	P10916	MYL2	Q15746	MYLK	T98	V105I	105	Missense	distal	7	no	1.295	1.288	EPSD	ICGC;COSMIC	1.165	Down-regulation
CAMK_MLCK_MYLK_ST	P24844	MYL9	Q15746	MYLK	T19	R14W	14	Missense	distal	-5	no	1.797	1.569	PhosphoSitePlus;EPSD	ICGC;COSMIC	1.165	Down-regulation
CAMK_MLCK_MYLK_ST	P24844	MYL9	Q15746	MYLK	S20	R17L	17	Missense	distal	-3	no	1.446	1.461	EPSD;PhosphoSitePlus	ICGC;COSMIC	1.165	Up-regulation
CAMK_MLCK_MYLK_ST	P24844	MYL9	Q15746	MYLK	S20	R14W	14	Missense	distal	-6	no	1.446	1.196	EPSD;PhosphoSitePlus	ICGC;COSMIC	1.165	Down-regulation
AGC_PKC_PKCa_PRKCG_ST	P07900	HSP90AA1	P05129	PRKCG	T5	E3K	3	Missense	proximal	-2	no	96.034	115.287	EPSD	ICGC	98.543	Gain
AGC_PKC_PKCa_PRKCG_ST	P07900	HSP90AA1	P05129	PRKCG	T7	E3K	3	Missense	distal	-4	no	109.654	111.232	EPSD	ICGC	98.543	Up-regulation
AGC_PKC_PKCa_PRKCG_ST	P07900	HSP90AA1	P05129	PRKCG	T19	Q23E	23	Missense	distal	4	no	108.390	105.755	EPSD	ICGC;COSMIC	98.543	Down-regulation
AGC_PKC_PKCa_PRKCG_ST	P07900	HSP90AA1	P05129	PRKCG	T19	E18K	18	Missense	proximal	-1	no	108.390	110.297	EPSD	ICGC;COSMIC	98.543	Up-regulation
AGC_PKC_PKCa_PRKCG_ST	P07900	HSP90AA1	P05129	PRKCG	T19	A24T	24	Missense	distal	5	no	108.390	109.965	EPSD	ICGC;COSMIC	98.543	Up-regulation
AGC_PKC_PKCa_PRKCG_ST	P07900	HSP90AA1	P05129	PRKCG	T19	F20L	20	Missense	proximal	1	no	108.390	109.311	EPSD	ICGC	98.543	Up-regulation
AGC_PKC_PKCa_PRKCG_ST	P07900	HSP90AA1	P05129	PRKCG	T19	E18D	18	Missense	proximal	-1	no	108.390	112.861	EPSD	ICGC;COSMIC	98.543	Up-regulation
AGC_PKC_PKCa_PRKCG_ST	P07900	HSP90AA1	P05129	PRKCG	S63	D66Y	66	Missense	distal	3	no	102.767	105.600	EPSD	ICGC;COSMIC	98.543	Up-regulation
AGC_PKC_PKCa_PRKCG_ST	P07900	HSP90AA1	P05129	PRKCG	S63	T65K	65	Missense	proximal	2	no	102.767	121.398	EPSD	ICGC	98.543	Up-regulation
AGC_PKC_PKCa_PRKCG_ST	P07900	HSP90AA1	P05129	PRKCG	S72	D66Y	66	Missense	distal	-6	no	104.224	101.969	EPSD	ICGC;COSMIC	98.543	Down-regulation
AGC_PKC_PKCa_PRKCG_ST	P07900	HSP90AA1	P05129	PRKCG	S72	I78V	78	Missense	distal	6	no	104.224	104.743	EPSD	ICGC;COSMIC	98.543	Up-regulation
AGC_PKC_PKCa_PRKCG_ST	P07900	HSP90AA1	P05129	PRKCG	S72	T65K	65	Missense	distal	-7	no	104.224	103.820	EPSD	ICGC	98.543	Down-regulation
AGC_PKC_PKCa_PRKCG_ST	P07900	HSP90AA1	P05129	PRKCG	S72	E75V	75	Missense	distal	3	no	104.224	99.032	EPSD	ICGC;COSMIC	98.543	Down-regulation
AGC_PKC_PKCa_PRKCG_ST	P07900	HSP90AA1	P05129	PRKCG	T115	A117S	117	Missense	proximal	2	no	121.566	126.870	PhosphoSitePlus;EPSD	ICGC;COSMIC	98.543	Up-regulation
AGC_PKC_PKCa_PRKCG_ST	P07900	HSP90AA1	P05129	PRKCG	T171	S165L	165	Missense	distal	-6	no	107.466	106.662	EPSD	ICGC;COSMIC	98.543	Down-regulation
AGC_PKC_PKCa_PRKCG_ST	P07900	HSP90AA1	P05129	PRKCG	T171	S164Y	164	Missense	distal	-7	no	107.466	105.181	EPSD	ICGC	98.543	Down-regulation
AGC_PKC_PKCa_PRKCG_ST	P07900	HSP90AA1	P05129	PRKCG	S211	G215A	215	Missense	distal	4	no	107.535	109.773	EPSD	ICGC;COSMIC	98.543	Up-regulation
AGC_PKC_PKCa_PRKCG_ST	P07900	HSP90AA1	P05129	PRKCG	S211	E205D	205	Missense	distal	-6	no	107.535	106.781	EPSD	ICGC;COSMIC	98.543	Down-regulation
AGC_PKC_PKCa_PRKCG_ST	P07900	HSP90AA1	P05129	PRKCG	S211	S211F	211	Missense	central	0	yes	107.535	0.000	EPSD	ICGC;COSMIC	98.543	Loss
AGC_PKC_PKCa_PRKCG_ST	P07900	HSP90AA1	P05129	PRKCG	S211	V207A	207	Missense	distal	-4	no	107.535	108.624	EPSD	ICGC;COSMIC	98.543	Up-regulation
AGC_PKC_PKCa_PRKCG_ST	P07900	HSP90AA1	P05129	PRKCG	T219	G215A	215	Missense	distal	-4	no	99.381	99.420	EPSD	ICGC;COSMIC	98.543	Up-regulation
AGC_PKC_PKCa_PRKCG_ST	P07900	HSP90AA1	P05129	PRKCG	T293	R299S	299	Missense	distal	6	no	108.463	103.217	EPSD	ICGC;COSMIC	98.543	Down-regulation
AGC_PKC_PKCa_PRKCG_ST	P07900	HSP90AA1	P05129	PRKCG	T293	N291S	291	Missense	proximal	-2	no	108.463	110.214	EPSD	ICGC;COSMIC	98.543	Up-regulation
AGC_PKC_PKCa_PRKCG_ST	P07900	HSP90AA1	P05129	PRKCG	S406	K410E	410	Missense	distal	4	no	111.263	106.781	EPSD	ICGC;COSMIC	98.543	Down-regulation
AGC_PKC_PKCa_PRKCG_ST	P07900	HSP90AA1	P05129	PRKCG	S406	Q405K	405	Missense	proximal	-1	no	111.263	113.778	EPSD	ICGC	98.543	Up-regulation
AGC_PKC_PKCa_PRKCG_ST	P07900	HSP90AA1	P05129	PRKCG	S406	S399T	399	Missense	distal	-7	no	111.263	111.809	EPSD	ICGC;COSMIC	98.543	Up-regulation
AGC_PKC_PKCa_PRKCG_ST	P07900	HSP90AA1	P05129	PRKCG	S460	E461G	461	Missense	proximal	1	no	112.598	108.325	EPSD	ICGC	98.543	Down-regulation
AGC_PKC_PKCa_PRKCG_ST	P07900	HSP90AA1	P05129	PRKCG	S460	R456Q	456	Missense	distal	-4	no	112.598	110.615	EPSD	ICGC;COSMIC	98.543	Down-regulation
AGC_PKC_PKCa_PRKCG_ST	P07900	HSP90AA1	P05129	PRKCG	S460	R464K	464	Missense	distal	4	no	112.598	113.627	EPSD	ICGC	98.543	Up-regulation
AGC_PKC_PKCa_PRKCG_ST	P07900	HSP90AA1	P05129	PRKCG	S460	L463S	463	Missense	distal	3	no	112.598	103.764	EPSD	ICGC;COSMIC	98.543	Down-regulation
AGC_PKC_PKCa_PRKCG_ST	P07900	HSP90AA1	P05129	PRKCG	S476	A469T	469	Missense	distal	-7	no	112.123	115.306	EPSD	ICGC	98.543	Up-regulation
AGC_PKC_PKCa_PRKCG_ST	P07900	HSP90AA1	P05129	PRKCG	S476	Y480H	480	Missense	distal	4	no	112.123	109.420	EPSD	ICGC;COSMIC	98.543	Down-regulation
AGC_PKC_PKCa_PRKCG_ST	P07900	HSP90AA1	P05129	PRKCG	T603	I599V	599	Missense	distal	-4	no	124.768	125.613	EPSD;PhosphoSitePlus	ICGC;COSMIC	98.543	Up-regulation
AGC_PKC_PKCa_PRKCG_ST	P07900	HSP90AA1	P05129	PRKCG	T603	Y604H	604	Missense	proximal	1	no	124.768	125.038	EPSD;PhosphoSitePlus	ICGC;COSMIC	98.543	Up-regulation
AGC_PKC_PKCa_PRKCG_ST	P07900	HSP90AA1	P05129	PRKCG	T603	V600I	600	Missense	distal	-3	no	124.768	117.678	EPSD;PhosphoSitePlus	ICGC;COSMIC	98.543	Down-regulation
AGC_PKC_PKCa_PRKCG_ST	P07900	HSP90AA1	P05129	PRKCG	T645	E644D	644	Missense	proximal	-1	no	95.739	100.211	EPSD	ICGC;COSMIC	98.543	Gain
AGC_PKC_PKCa_PRKCG_ST	Q9H3Z4	DNAJC5	P05129	PRKCG	S10	L16F	16	Missense	distal	6	no	128.222	130.128	EPSD;PhosphoSitePlus	ICGC	98.543	Up-regulation
AGC_PKC_PKCa_PRKCG_ST	Q9H3Z4	DNAJC5	P05129	PRKCG	T11	L16F	16	Missense	distal	5	no	108.632	113.787	EPSD	ICGC	98.543	Up-regulation
AGC_PKC_PKCa_PRKCG_ST	Q9H3Z4	DNAJC5	P05129	PRKCG	S15	L16F	16	Missense	proximal	1	no	105.998	105.076	EPSD	ICGC	98.543	Down-regulation
AGC_PKC_PKCa_PRKCG_ST	Q9H3Z4	DNAJC5	P05129	PRKCG	S34	I31V	31	Missense	distal	-3	no	135.866	142.956	PhosphoSitePlus;EPSD	ICGC;COSMIC	98.543	Up-regulation
AGC_PKC_PKCa_PRKCG_ST	Q9H3Z4	DNAJC5	P05129	PRKCG	T146	T146M	146	Missense	central	0	yes	107.427	0.000	EPSD	ICGC;COSMIC	98.543	Loss
AGC_PKC_PKCa_PRKCG_ST	P10636	MAPT	P05129	PRKCG	S341	T346I	346	Missense	distal	5	no	119.427	109.434	EPSD	ICGC;COSMIC	98.543	Down-regulation
AGC_PKC_PKCa_PRKCG_ST	P10636	MAPT	P05129	PRKCG	S341	A337V	337	Missense	distal	-4	no	119.427	118.338	EPSD	ICGC	98.543	Down-regulation
AGC_PKC_PKCa_PRKCG_ST	P10636	MAPT	P05129	PRKCG	S341	D345E	345	Missense	distal	4	no	119.427	117.634	EPSD	ICGC;COSMIC	98.543	Down-regulation
AGC_PKC_PKCa_PRKCG_ST	P10636	MAPT	P05129	PRKCG	S355	A349T	349	Missense	distal	-6	no	100.712	99.736	EPSD	ICGC;COSMIC	98.543	Down-regulation
AGC_PKC_PKCa_PRKCG_ST	P98082	DAB2	P05129	PRKCG	S2	N3H	3	Missense	proximal	1	no	101.006	100.199	EPSD	ICGC;COSMIC	98.543	Down-regulation
AGC_PKC_PKCa_PRKCG_ST	P98082	DAB2	P05129	PRKCG	T7	P14T	14	Missense	distal	7	no	101.563	103.496	EPSD	ICGC	98.543	Up-regulation
AGC_PKC_PKCa_PRKCG_ST	P98082	DAB2	P05129	PRKCG	T7	N3H	3	Missense	distal	-4	no	101.563	101.257	EPSD	ICGC;COSMIC	98.543	Down-regulation
AGC_PKC_PKCa_PRKCG_ST	P98082	DAB2	P05129	PRKCG	S8	D15N	15	Missense	distal	7	no	120.522	134.091	EPSD	ICGC;COSMIC	98.543	Up-regulation
AGC_PKC_PKCa_PRKCG_ST	P98082	DAB2	P05129	PRKCG	S8	P14T	14	Missense	distal	6	no	120.522	116.710	EPSD	ICGC	98.543	Down-regulation
AGC_PKC_PKCa_PRKCG_ST	P98082	DAB2	P05129	PRKCG	S8	N3H	3	Missense	distal	-5	no	120.522	121.911	EPSD	ICGC;COSMIC	98.543	Up-regulation
AGC_PKC_PKCa_PRKCG_ST	P98082	DAB2	P05129	PRKCG	T10	D15N	15	Missense	distal	5	no	106.074	109.854	EPSD	ICGC;COSMIC	98.543	Up-regulation
AGC_PKC_PKCa_PRKCG_ST	P98082	DAB2	P05129	PRKCG	T10	P14T	14	Missense	distal	4	no	106.074	106.465	EPSD	ICGC	98.543	Up-regulation
AGC_PKC_PKCa_PRKCG_ST	P98082	DAB2	P05129	PRKCG	T10	Q16K	16	Missense	distal	6	no	106.074	109.352	EPSD	ICGC;COSMIC	98.543	Up-regulation
AGC_PKC_PKCa_PRKCG_ST	P98082	DAB2	P05129	PRKCG	T10	N3H	3	Missense	distal	-7	no	106.074	107.857	EPSD	ICGC;COSMIC	98.543	Up-regulation
AGC_PKC_PKCa_PRKCG_ST	P98082	DAB2	P05129	PRKCG	S24	A19S	19	Missense	distal	-5	no	142.045	140.255	PhosphoSitePlus	ICGC	98.543	Down-regulation
AGC_PKC_PKCa_PRKCG_ST	P98082	DAB2	P05129	PRKCG	S249	S249C	249	Missense	central	0	yes	101.481	0.000	EPSD	ICGC;COSMIC	98.543	Loss
AGC_PKC_PKCa_PRKCG_ST	P98082	DAB2	P05129	PRKCG	S249	T245A	245	Missense	distal	-4	no	101.481	101.284	EPSD	ICGC;COSMIC	98.543	Down-regulation
AGC_PKC_PKCa_PRKCG_ST	P98082	DAB2	P05129	PRKCG	S249	Q247K	247	Missense	proximal	-2	no	101.481	109.419	EPSD	ICGC	98.543	Up-regulation
AGC_PKC_PKCa_PRKCG_ST	P98082	DAB2	P05129	PRKCG	S249	P254L	254	Missense	distal	5	no	101.481	99.755	EPSD	ICGC	98.543	Down-regulation
AGC_PKC_PKCa_PRKCG_ST	P98082	DAB2	P05129	PRKCG	S436	P433H	433	Missense	distal	-3	no	100.881	110.238	EPSD	ICGC;COSMIC	98.543	Up-regulation
AGC_PKC_PKCa_PRKCG_ST	P98082	DAB2	P05129	PRKCG	S688	P693Q	693	Missense	distal	5	no	109.302	116.695	EPSD	ICGC	98.543	Up-regulation
AGC_PKC_PKCa_PRKCG_ST	Q03721	KCNC4	P05129	PRKCG	S8	K14N	14	Missense	distal	6	no	124.337	123.203	PhosphoSitePlus;EPSD	ICGC	98.543	Down-regulation
AGC_PKC_PKCa_PRKCG_ST	Q03721	KCNC4	P05129	PRKCG	S9	K14N	14	Missense	distal	5	no	165.875	156.606	EPSD;PhosphoSitePlus	ICGC	98.543	Down-regulation
AGC_PKC_PKCa_PRKCG_ST	Q03721	KCNC4	P05129	PRKCG	S15	K14N	14	Missense	proximal	-1	no	135.219	133.780	EPSD;PhosphoSitePlus	ICGC	98.543	Down-regulation
AGC_PKC_PKCa_PRKCG_ST	Q03721	KCNC4	P05129	PRKCG	S21	K14N	14	Missense	distal	-7	no	135.397	133.802	EPSD;PhosphoSitePlus	ICGC	98.543	Down-regulation
AGC_PKC_PKCa_PRKCG_ST	Q03721	KCNC4	P05129	PRKCG	T49	T56P	56	Missense	distal	7	no	109.119	107.185	EPSD	ICGC;COSMIC	98.543	Down-regulation
AGC_PKC_PKCa_PRKCG_ST	Q03721	KCNC4	P05129	PRKCG	T49	L54M	54	Missense	distal	5	no	109.119	115.942	EPSD	ICGC;COSMIC	98.543	Up-regulation
AGC_PKC_PKCa_PRKCG_ST	Q03721	KCNC4	P05129	PRKCG	T567	E569K	569	Missense	proximal	2	no	73.785	105.737	EPSD	ICGC;COSMIC;CCLE	98.543	Gain
AGC_PKC_PKCa_PRKCG_ST	Q03721	KCNC4	P05129	PRKCG	T578	R576H	576	Missense	proximal	-2	no	118.699	115.972	EPSD	ICGC;COSMIC	98.543	Down-regulation
AGC_PKC_PKCa_PRKCG_ST	P43629	KIR3DL1	P05129	PRKCG	S415	T412M	412	Missense	distal	-3	no	129.110	116.445	PhosphoSitePlus	ICGC;COSMIC	98.543	Down-regulation
AGC_PKC_PKCa_PRKCG_ST	P43629	KIR3DL1	P05129	PRKCG	S415	P418T	418	Missense	distal	3	no	129.110	123.354	PhosphoSitePlus	ICGC	98.543	Down-regulation
AGC_PKC_PKCa_PRKCG_ST	P43629	KIR3DL1	P05129	PRKCG	S415	P414T	414	Missense	proximal	-1	no	129.110	130.291	PhosphoSitePlus	ICGC	98.543	Up-regulation
AGC_PKC_PKCa_PRKCG_ST	P43629	KIR3DL1	P05129	PRKCG	S415	Q416L	416	Missense	proximal	1	no	129.110	134.514	PhosphoSitePlus	ICGC	98.543	Up-regulation
AGC_PKC_PKCa_PRKCG_ST	P43629	KIR3DL1	P05129	PRKCG	S415	R413L	413	Missense	proximal	-2	no	129.110	122.633	PhosphoSitePlus	ICGC;COSMIC	98.543	Down-regulation
AGC_PKC_PKCa_PRKCG_ST	P43629	KIR3DL1	P05129	PRKCG	S415	P418L	418	Missense	distal	3	no	129.110	130.938	PhosphoSitePlus	ICGC	98.543	Up-regulation
AGC_PKC_PKCa_PRKCG_ST	P49841	GSK3B	P05129	PRKCG	T7	A11S	11	Missense	distal	4	no	116.006	114.707	EPSD	ICGC;COSMIC	98.543	Down-regulation
AGC_PKC_PKCa_PRKCG_ST	P49841	GSK3B	P05129	PRKCG	T8	A11S	11	Missense	distal	3	no	103.139	101.323	EPSD	ICGC;COSMIC	98.543	Down-regulation
AGC_PKC_PKCa_PRKCG_ST	P49841	GSK3B	P05129	PRKCG	S9	A11S	11	Missense	proximal	2	no	131.312	136.616	PhosphoSitePlus	ICGC;COSMIC	98.543	Up-regulation
AGC_PKC_PKCa_PRKCG_ST	P49841	GSK3B	P05129	PRKCG	S13	A11S	11	Missense	proximal	-2	no	109.051	111.429	EPSD	ICGC;COSMIC	98.543	Up-regulation
AGC_PKC_PKCa_PRKCG_ST	P49841	GSK3B	P05129	PRKCG	S35	D33E	33	Missense	proximal	-2	no	104.123	103.432	EPSD	ICGC	98.543	Down-regulation
AGC_PKC_PKCa_PRKCG_ST	P49841	GSK3B	P05129	PRKCG	T408	G406R	406	Missense	proximal	-2	no	89.973	98.546	EPSD	ICGC;COSMIC	98.543	Gain
AGC_PKC_PKCa_PRKCG_ST	Q13507	TRPC3	P05129	PRKCG	S380	L385I	385	Missense	distal	5	no	114.207	107.659	EPSD	ICGC;COSMIC	98.543	Down-regulation
AGC_PKC_PKCa_PRKCG_ST	P50281	MMP14	P05129	PRKCG	T567	R564C	564	Missense	distal	-3	no	106.586	79.014	PhosphoSitePlus	ICGC;COSMIC	98.543	Loss
AGC_PKC_PKCa_PRKCG_ST	P50281	MMP14	P05129	PRKCG	T567	R570L	570	Missense	distal	3	no	106.586	103.056	PhosphoSitePlus	ICGC	98.543	Down-regulation
AGC_PKC_PKCa_PRKCG_ST	P50281	MMP14	P05129	PRKCG	T567	H565R	565	Missense	proximal	-2	no	106.586	109.314	PhosphoSitePlus	ICGC;COSMIC	98.543	Up-regulation
AGC_PKC_PKCa_PRKCG_ST	Q9UBS0	RPS6KB2	P05129	PRKCG	T11	E13K	13	Missense	proximal	2	no	88.740	120.692	EPSD	ICGC	98.543	Gain
AGC_PKC_PKCa_PRKCG_ST	Q9UBS0	RPS6KB2	P05129	PRKCG	S15	E13K	13	Missense	proximal	-2	no	122.067	141.321	EPSD	ICGC	98.543	Up-regulation
AGC_PKC_PKCa_PRKCG_ST	Q9UBS0	RPS6KB2	P05129	PRKCG	S15	E22K	22	Missense	distal	7	no	122.067	121.044	EPSD	ICGC;COSMIC	98.543	Down-regulation
AGC_PKC_PKCa_PRKCG_ST	Q9UBS0	RPS6KB2	P05129	PRKCG	S219	C216G	216	Missense	distal	-3	no	91.966	108.220	EPSD	ICGC	98.543	Gain
AGC_PKC_PKCa_PRKCG_ST	Q9UBS0	RPS6KB2	P05129	PRKCG	S266	P267L	267	Missense	proximal	1	no	103.558	117.692	EPSD	ICGC;COSMIC	98.543	Up-regulation
AGC_PKC_PKCa_PRKCG_ST	Q9UBS0	RPS6KB2	P05129	PRKCG	S266	S266L	266	Missense	central	0	yes	103.558	0.000	EPSD	ICGC;COSMIC	98.543	Loss
AGC_PKC_PKCa_PRKCG_ST	Q9UBS0	RPS6KB2	P05129	PRKCG	S410	F404L	404	Missense	distal	-6	no	110.155	106.517	EPSD	ICGC	98.543	Down-regulation
AGC_PKC_PKCa_PRKCG_ST	Q9UBS0	RPS6KB2	P05129	PRKCG	S416	V422I	422	Missense	distal	6	no	98.869	98.350	EPSD	ICGC;COSMIC;CCLE	98.543	Loss
AGC_PKC_PKCa_PRKCG_ST	Q9UBS0	RPS6KB2	P05129	PRKCG	S416	A420V	420	Missense	distal	4	no	98.869	92.140	EPSD	ICGC;COSMIC	98.543	Loss
AGC_PKC_PKCa_PRKCG_ST	Q9UBS0	RPS6KB2	P05129	PRKCG	S436	R434W	434	Missense	proximal	-2	no	98.543	81.358	EPSD	ICGC;COSMIC	98.543	Loss
AGC_PKC_PKCa_PRKCG_ST	Q9UBS0	RPS6KB2	P05129	PRKCG	S436	S438N	438	Missense	proximal	2	no	98.543	105.228	EPSD	ICGC;COSMIC	98.543	Up-regulation
AGC_PKC_PKCa_PRKCG_ST	Q9UBS0	RPS6KB2	P05129	PRKCG	S436	E441V	441	Missense	distal	5	no	98.543	96.417	EPSD	ICGC	98.543	Loss
AGC_PKC_PKCa_PRKCG_ST	Q9UBS0	RPS6KB2	P05129	PRKCG	S436	S436I	436	Missense	central	0	yes	98.543	0.000	EPSD	ICGC	98.543	Loss
AGC_PKC_PKCa_PRKCG_ST	Q9UBS0	RPS6KB2	P05129	PRKCG	S436	P437S	437	Missense	proximal	1	no	98.543	101.058	EPSD	ICGC	98.543	Up-regulation
AGC_PKC_PKCa_PRKCG_ST	Q9UBS0	RPS6KB2	P05129	PRKCG	S436	P429H	429	Missense	distal	-7	no	98.543	101.154	EPSD	ICGC;COSMIC	98.543	Up-regulation
AGC_PKC_PKCa_PRKCG_ST	Q9UBS0	RPS6KB2	P05129	PRKCG	S438	P437S	437	Missense	proximal	-1	no	95.351	100.416	EPSD	ICGC	98.543	Gain
AGC_PKC_PKCa_PRKCG_ST	Q14155	ARHGEF7	P05129	PRKCG	S19	D26N	26	Missense	distal	7	no	103.720	117.288	EPSD	ICGC;COSMIC	98.543	Up-regulation
AGC_PKC_PKCa_PRKCG_ST	Q14155	ARHGEF7	P05129	PRKCG	S19	K21T	21	Missense	proximal	2	no	103.720	85.088	EPSD	ICGC;COSMIC	98.543	Loss
AGC_PKC_PKCa_PRKCG_ST	Q14155	ARHGEF7	P05129	PRKCG	T23	D26N	26	Missense	distal	3	no	122.016	129.177	EPSD	ICGC;COSMIC	98.543	Up-regulation
AGC_PKC_PKCa_PRKCG_ST	Q14155	ARHGEF7	P05129	PRKCG	T23	K21T	21	Missense	proximal	-2	no	122.016	117.702	EPSD	ICGC;COSMIC	98.543	Down-regulation
AGC_PKC_PKCa_PRKCG_ST	Q14155	ARHGEF7	P05129	PRKCG	T23	E28K	28	Missense	distal	5	no	122.016	133.961	EPSD	ICGC;COSMIC	98.543	Up-regulation
AGC_PKC_PKCa_PRKCG_ST	Q14155	ARHGEF7	P05129	PRKCG	T23	G29D	29	Missense	distal	6	no	122.016	119.107	EPSD	ICGC	98.543	Down-regulation
AGC_PKC_PKCa_PRKCG_ST	Q14155	ARHGEF7	P05129	PRKCG	S25	D26N	26	Missense	proximal	1	no	94.850	104.849	EPSD	ICGC;COSMIC	98.543	Gain
AGC_PKC_PKCa_PRKCG_ST	Q14155	ARHGEF7	P05129	PRKCG	T254	G261E	261	Missense	distal	7	no	111.855	118.739	EPSD	ICGC	98.543	Up-regulation
AGC_PKC_PKCa_PRKCG_ST	Q14155	ARHGEF7	P05129	PRKCG	S295	R299W	299	Missense	distal	4	no	100.873	90.862	EPSD	ICGC;COSMIC	98.543	Loss
AGC_PKC_PKCa_PRKCG_ST	Q14155	ARHGEF7	P05129	PRKCG	S605	H600Y	600	Missense	distal	-5	no	104.992	103.844	EPSD	ICGC;CCLE	98.543	Down-regulation
AGC_PKC_PKCa_PRKCG_ST	Q14155	ARHGEF7	P05129	PRKCG	S674	M680R	680	Missense	distal	6	no	103.244	106.560	EPSD	ICGC;COSMIC	98.543	Up-regulation
AGC_PKC_PKCa_PRKCG_ST	Q14155	ARHGEF7	P05129	PRKCG	S676	M680R	680	Missense	distal	4	no	102.368	109.628	EPSD	ICGC;COSMIC	98.543	Up-regulation
AGC_PKC_PKCa_PRKCG_ST	Q14155	ARHGEF7	P05129	PRKCG	T679	M680R	680	Missense	proximal	1	no	105.583	109.112	EPSD	ICGC;COSMIC	98.543	Up-regulation
AGC_PKC_PKCa_PRKCG_ST	Q14155	ARHGEF7	P05129	PRKCG	S723	V716F	716	Missense	distal	-7	no	99.724	103.534	EPSD	ICGC	98.543	Up-regulation
AGC_PKC_PKCa_PRKCG_ST	Q14155	ARHGEF7	P05129	PRKCG	S761	R758H	758	Missense	distal	-3	no	124.385	121.626	EPSD;PhosphoSitePlus	ICGC;COSMIC	98.543	Down-regulation
AGC_PKC_PKCa_PRKCG_ST	Q14155	ARHGEF7	P05129	PRKCG	S761	R764L	764	Missense	distal	3	no	124.385	120.854	EPSD;PhosphoSitePlus	ICGC	98.543	Down-regulation
AGC_PKC_PKCa_PRKCG_ST	Q14155	ARHGEF7	P05129	PRKCG	S761	E766D	766	Missense	distal	5	no	124.385	123.280	EPSD;PhosphoSitePlus	ICGC	98.543	Down-regulation
AGC_PKC_PKCa_PRKCG_ST	Q14155	ARHGEF7	P05129	PRKCG	S761	G757R	757	Missense	distal	-4	no	124.385	125.091	EPSD;PhosphoSitePlus	ICGC	98.543	Up-regulation
AGC_PKC_PKCa_PRKCG_ST	P21730	C5AR1	P05129	PRKCG	S314	R312W	312	Missense	proximal	-2	no	108.132	90.947	EPSD	ICGC;COSMIC	98.543	Loss
AGC_PKC_PKCa_PRKCG_ST	P21730	C5AR1	P05129	PRKCG	S317	R312W	312	Missense	distal	-5	no	98.724	103.729	EPSD	ICGC;COSMIC	98.543	Up-regulation
AGC_PKC_PKCa_PRKCG_ST	P21730	C5AR1	P05129	PRKCG	S317	L323F	323	Missense	distal	6	no	98.724	100.630	EPSD	ICGC;COSMIC	98.543	Up-regulation
AGC_PKC_PKCa_PRKCG_ST	P21730	C5AR1	P05129	PRKCG	S327	S327F	327	Missense	central	0	yes	106.879	0.000	EPSD	ICGC	98.543	Loss
AGC_PKC_PKCa_PRKCG_ST	P21730	C5AR1	P05129	PRKCG	S327	L323F	323	Missense	distal	-4	no	106.879	107.569	EPSD	ICGC;COSMIC	98.543	Up-regulation
AGC_PKC_PKCa_PRKCG_ST	P21730	C5AR1	P05129	PRKCG	S334	R337C	337	Missense	distal	3	no	102.791	90.171	PhosphoSitePlus	ICGC;COSMIC;CCLE	98.543	Loss
AGC_PKC_PKCa_PRKCG_ST	P21730	C5AR1	P05129	PRKCG	S334	S327F	327	Missense	distal	-7	no	102.791	102.096	PhosphoSitePlus	ICGC	98.543	Down-regulation
AGC_PKC_PKCa_PRKCG_ST	P06127	CD5	P05129	PRKCG	S309	R307M	307	Missense	proximal	-2	no	101.124	95.977	EPSD	ICGC;COSMIC	98.543	Loss
AGC_PKC_PKCa_PRKCG_ST	P06127	CD5	P05129	PRKCG	S309	A306D	306	Missense	distal	-3	no	101.124	100.705	EPSD	ICGC;COSMIC	98.543	Down-regulation
AGC_PKC_PKCa_PRKCG_ST	P06127	CD5	P05129	PRKCG	T434	S428Y	428	Missense	distal	-6	no	123.839	119.780	PhosphoSitePlus;EPSD	ICGC	98.543	Down-regulation
AGC_PKC_PKCa_PRKCG_ST	P06127	CD5	P05129	PRKCG	T434	A435S	435	Missense	proximal	1	no	123.839	121.607	PhosphoSitePlus;EPSD	ICGC	98.543	Down-regulation
AGC_PKC_PKCa_PRKCG_ST	P06127	CD5	P05129	PRKCG	T434	V437F	437	Missense	distal	3	no	123.839	125.928	PhosphoSitePlus;EPSD	ICGC	98.543	Up-regulation
AGC_PKC_PKCa_PRKCG_ST	P06127	CD5	P05129	PRKCG	T436	A435S	435	Missense	proximal	-1	no	119.055	122.582	EPSD;PhosphoSitePlus	ICGC	98.543	Up-regulation
AGC_PKC_PKCa_PRKCG_ST	P06127	CD5	P05129	PRKCG	T436	V437F	437	Missense	proximal	1	no	119.055	125.972	EPSD;PhosphoSitePlus	ICGC	98.543	Up-regulation
AGC_PKC_PKCa_PRKCG_ST	P06127	CD5	P05129	PRKCG	S476	A471V	471	Missense	distal	-5	no	95.356	99.247	EPSD	ICGC	98.543	Gain
AGC_PKC_PKCa_PRKCG_ST	P28329	CHAT	P05129	PRKCG	S594	L597F	597	Missense	distal	3	no	127.395	128.504	EPSD	ICGC;COSMIC	98.543	Up-regulation
AGC_PKC_PKCa_PRKCG_ST	P28329	CHAT	P05129	PRKCG	S594	A590T	590	Missense	distal	-4	no	127.395	127.591	EPSD	ICGC;COSMIC	98.543	Up-regulation
AGC_PKC_PKCa_PRKCG_ST	P49840	GSK3A	P05129	PRKCG	S97	D96E	96	Missense	proximal	-1	no	113.865	109.393	EPSD	ICGC;COSMIC	98.543	Down-regulation
AGC_PKC_PKCa_PRKCG_ST	P49840	GSK3A	P05129	PRKCG	S97	R95G	95	Missense	proximal	-2	no	113.865	105.292	EPSD	ICGC;COSMIC	98.543	Down-regulation
AGC_PKC_PKCa_PRKCG_ST	P49840	GSK3A	P05129	PRKCG	S97	G98R	98	Missense	proximal	1	no	113.865	121.756	EPSD	ICGC	98.543	Up-regulation
AGC_PKC_PKCa_PRKCG_ST	P49840	GSK3A	P05129	PRKCG	S97	V103A	103	Missense	distal	6	no	113.865	114.344	EPSD	ICGC;COSMIC	98.543	Up-regulation
AGC_PKC_PKCa_PRKCG_ST	P49840	GSK3A	P05129	PRKCG	S129	G128D	128	Missense	proximal	-1	no	94.825	99.014	EPSD	ICGC;COSMIC	98.543	Gain
TK_PDGFR_FLT3_Y	P36888	FLT3	P36888	FLT3	Y572	L576P	576	Missense	distal	4	no	1.348	1.090	EPSD	ICGC;COSMIC	0.779	Down-regulation
TK_PDGFR_FLT3_Y	P36888	FLT3	P36888	FLT3	Y589	Y589H	589	Missense	central	0	yes	1.059	0.000	EPSD;PhosphoSitePlus	ICGC;COSMIC	0.779	Loss
TK_PDGFR_FLT3_Y	P36888	FLT3	P36888	FLT3	Y591	Y589H	589	Missense	proximal	-2	no	1.561	1.567	EPSD;PhosphoSitePlus	ICGC;COSMIC	0.779	Up-regulation
TK_PDGFR_FLT3_Y	P36888	FLT3	P36888	FLT3	Y597	D600Y	600	Missense	distal	3	no	1.311	1.303	EPSD	ICGC;COSMIC	0.779	Down-regulation
TK_PDGFR_FLT3_Y	P36888	FLT3	P36888	FLT3	Y599	D600Y	600	Missense	proximal	1	no	1.199	1.203	EPSD;PhosphoSitePlus	ICGC;COSMIC	0.779	Up-regulation
TK_PDGFR_FLT3_Y	P36888	FLT3	P36888	FLT3	Y599	P606S	606	Missense	distal	7	no	1.199	1.207	EPSD;PhosphoSitePlus	ICGC	0.779	Up-regulation
TK_PDGFR_FLT3_Y	P36888	FLT3	P36888	FLT3	Y842	D835V	835	Missense	distal	-7	no	1.234	1.220	EPSD;PhosphoSitePlus	ICGC;COSMIC	0.779	Down-regulation
TK_PDGFR_FLT3_Y	P36888	FLT3	P36888	FLT3	Y842	M837T	837	Missense	distal	-5	no	1.234	1.246	EPSD;PhosphoSitePlus	ICGC;COSMIC	0.779	Up-regulation
TK_PDGFR_FLT3_Y	P36888	FLT3	P36888	FLT3	Y842	Y842C	842	Missense	central	0	yes	1.234	0.000	EPSD;PhosphoSitePlus	ICGC;COSMIC	0.779	Loss
TK_PDGFR_FLT3_Y	P36888	FLT3	P36888	FLT3	Y842	D835Y	835	Missense	distal	-7	no	1.234	1.231	EPSD;PhosphoSitePlus	ICGC;COSMIC	0.779	Down-regulation
TK_PDGFR_FLT3_Y	P36888	FLT3	P36888	FLT3	Y842	D835H	835	Missense	distal	-7	no	1.234	1.231	EPSD;PhosphoSitePlus	ICGC;COSMIC;CCLE	0.779	Down-regulation
TK_PDGFR_FLT3_Y	P36888	FLT3	P36888	FLT3	Y842	D835N	835	Missense	distal	-7	no	1.234	1.253	EPSD;PhosphoSitePlus	ICGC;COSMIC	0.779	Up-regulation
TK_PDGFR_FLT3_Y	P36888	FLT3	P36888	FLT3	Y842	D835E	835	Missense	distal	-7	no	1.234	1.215	EPSD;PhosphoSitePlus	ICGC;COSMIC	0.779	Down-regulation
TK_PDGFR_FLT3_Y	P36888	FLT3	P36888	FLT3	Y842	N841K	841	Missense	proximal	-1	no	1.234	1.223	EPSD;PhosphoSitePlus	ICGC;COSMIC	0.779	Down-regulation
TK_PDGFR_FLT3_Y	P36888	FLT3	P36888	FLT3	Y842	R845M	845	Missense	distal	3	no	1.234	1.231	EPSD;PhosphoSitePlus	ICGC;COSMIC	0.779	Down-regulation
TK_PDGFR_FLT3_Y	Q15118	PDK1	P36888	FLT3	Y243	C240F	240	Missense	distal	-3	no	1.394	1.442	PhosphoSitePlus	ICGC;COSMIC	0.779	Up-regulation
TK_PDGFR_FLT3_Y	Q15118	PDK1	P36888	FLT3	Y243	R238C	238	Missense	distal	-5	no	1.394	1.393	PhosphoSitePlus	ICGC	0.779	Down-regulation
TK_PDGFR_FLT3_Y	Q15118	PDK1	P36888	FLT3	Y243	P248H	248	Missense	distal	5	no	1.394	1.390	PhosphoSitePlus	ICGC;COSMIC	0.779	Down-regulation
CMGC_SRPK_SRPK1_ST	Q07955	SRSF1	Q96SB4	SRPK1	S91	T95K	95	Missense	distal	4	no	55.432	62.055	EPSD	ICGC	48.822	Up-regulation
CMGC_SRPK_SRPK1_ST	Q07955	SRSF1	Q96SB4	SRPK1	S91	S91R	91	Missense	central	0	yes	55.432	0.000	EPSD	ICGC	48.822	Loss
CMGC_SRPK_SRPK1_ST	Q07955	SRSF1	Q96SB4	SRPK1	S91	R93S	93	Missense	proximal	2	no	55.432	66.460	EPSD	ICGC	48.822	Up-regulation
CMGC_SRPK_SRPK1_ST	Q07955	SRSF1	Q96SB4	SRPK1	S91	R97Q	97	Missense	distal	6	no	55.432	47.390	EPSD	ICGC;COSMIC	48.822	Loss
CMGC_SRPK_SRPK1_ST	Q07955	SRSF1	Q96SB4	SRPK1	S119	S126C	126	Missense	distal	7	no	68.718	66.508	EPSD	ICGC;COSMIC	48.822	Down-regulation
CMGC_SRPK_SRPK1_ST	Q07955	SRSF1	Q96SB4	SRPK1	S119	S126P	126	Missense	distal	7	no	68.718	68.537	EPSD	ICGC;COSMIC;GDSC;CCLE	48.822	Down-regulation
CMGC_SRPK_SRPK1_ST	Q07955	SRSF1	Q96SB4	SRPK1	S131	S126C	126	Missense	distal	-5	no	50.381	49.601	EPSD	ICGC;COSMIC	48.822	Down-regulation
CMGC_SRPK_SRPK1_ST	Q07955	SRSF1	Q96SB4	SRPK1	S131	P129H	129	Missense	proximal	-2	no	50.381	46.224	EPSD	ICGC	48.822	Loss
CMGC_SRPK_SRPK1_ST	Q07955	SRSF1	Q96SB4	SRPK1	S131	S126P	126	Missense	distal	-5	no	50.381	51.760	EPSD	ICGC;COSMIC;GDSC;CCLE	48.822	Up-regulation
CMGC_SRPK_SRPK1_ST	Q07955	SRSF1	Q96SB4	SRPK1	S131	W134S	134	Missense	distal	3	no	50.381	52.841	EPSD	ICGC;COSMIC	48.822	Up-regulation
CMGC_SRPK_SRPK1_ST	Q07955	SRSF1	Q96SB4	SRPK1	S199	K193T	193	Missense	distal	-6	no	117.477	112.012	EPSD	ICGC	48.822	Down-regulation
CMGC_SRPK_SRPK1_ST	Q07955	SRSF1	Q96SB4	SRPK1	S199	S199I	199	Missense	central	0	yes	117.477	0.000	EPSD	ICGC	48.822	Loss
CMGC_SRPK_SRPK1_ST	Q07955	SRSF1	Q96SB4	SRPK1	S201	S199I	199	Missense	proximal	-2	no	152.604	138.733	EPSD	ICGC	48.822	Down-regulation
CMGC_SRPK_SRPK1_ST	Q07955	SRSF1	Q96SB4	SRPK1	S205	S199I	199	Missense	distal	-6	no	202.596	195.018	EPSD;PhosphoSitePlus	ICGC	48.822	Down-regulation
CMGC_SRPK_SRPK1_ST	Q07955	SRSF1	Q96SB4	SRPK1	S225	S231R	231	Missense	distal	6	no	256.763	253.262	EPSD;PhosphoSitePlus	ICGC	48.822	Down-regulation
CMGC_SRPK_SRPK1_ST	Q07955	SRSF1	Q96SB4	SRPK1	S227	S231R	231	Missense	distal	4	no	221.842	217.458	EPSD;PhosphoSitePlus	ICGC	48.822	Down-regulation
CMGC_SRPK_SRPK1_ST	Q07955	SRSF1	Q96SB4	SRPK1	S231	S231R	231	Missense	central	0	yes	185.483	0.000	EPSD	ICGC	48.822	Loss
CMGC_SRPK_SRPK1_ST	Q07955	SRSF1	Q96SB4	SRPK1	S234	P239H	239	Missense	distal	5	no	75.861	73.444	EPSD	ICGC	48.822	Down-regulation
CMGC_SRPK_SRPK1_ST	Q07955	SRSF1	Q96SB4	SRPK1	S234	S231R	231	Missense	distal	-3	no	75.861	114.080	EPSD	ICGC	48.822	Up-regulation
CMGC_SRPK_SRPK1_ST	Q07955	SRSF1	Q96SB4	SRPK1	S238	P239H	239	Missense	proximal	1	no	127.457	125.386	EPSD	ICGC	48.822	Down-regulation
CMGC_SRPK_SRPK1_ST	Q07955	SRSF1	Q96SB4	SRPK1	S238	S231R	231	Missense	distal	-7	no	127.457	142.432	EPSD	ICGC	48.822	Up-regulation
CMGC_SRPK_SRPK1_ST	Q07955	SRSF1	Q96SB4	SRPK1	S242	P239H	239	Missense	distal	-3	no	125.873	121.835	EPSD	ICGC	48.822	Down-regulation
CMGC_SRPK_SRPK1_ST	Q07955	SRSF1	Q96SB4	SRPK1	S244	P239H	239	Missense	distal	-5	no	126.258	125.064	EPSD	ICGC	48.822	Down-regulation
CMGC_SRPK_SRPK1_ST	Q07955	SRSF1	Q96SB4	SRPK1	S246	P239H	239	Missense	distal	-7	no	135.367	132.908	EPSD	ICGC	48.822	Down-regulation
CMGC_SRPK_SRPK1_ST	Q9BWF3	RBM4	Q96SB4	SRPK1	S146	R149W	149	Missense	distal	3	no	56.303	34.330	EPSD	ICGC;COSMIC	48.822	Loss
CMGC_SRPK_SRPK1_ST	Q9BWF3	RBM4	Q96SB4	SRPK1	S146	A153V	153	Missense	distal	7	no	56.303	56.212	EPSD	ICGC;COSMIC	48.822	Down-regulation
CMGC_SRPK_SRPK1_ST	Q9BWF3	RBM4	Q96SB4	SRPK1	S146	M141I	141	Missense	distal	-5	no	56.303	54.648	EPSD	ICGC;COSMIC	48.822	Down-regulation
CMGC_SRPK_SRPK1_ST	Q9BWF3	RBM4	Q96SB4	SRPK1	S146	V143L	143	Missense	distal	-3	no	56.303	58.069	EPSD	ICGC	48.822	Up-regulation
CMGC_SRPK_SRPK1_ST	Q9BWF3	RBM4	Q96SB4	SRPK1	S146	R149L	149	Missense	distal	3	no	56.303	33.424	EPSD	ICGC	48.822	Loss
CMGC_SRPK_SRPK1_ST	Q9BWF3	RBM4	Q96SB4	SRPK1	S146	L145F	145	Missense	proximal	-1	no	56.303	58.335	EPSD	ICGC	48.822	Up-regulation
CMGC_SRPK_SRPK1_ST	Q9BWF3	RBM4	Q96SB4	SRPK1	S146	R140Q	140	Missense	distal	-6	no	56.303	53.271	EPSD	ICGC;COSMIC	48.822	Down-regulation
CMGC_SRPK_SRPK1_ST	Q9BWF3	RBM4	Q96SB4	SRPK1	S146	S146F	146	Missense	central	0	yes	56.303	0.000	EPSD	ICGC;COSMIC	48.822	Loss
CMGC_SRPK_SRPK1_ST	Q9BWF3	RBM4	Q96SB4	SRPK1	S146	A153T	153	Missense	distal	7	no	56.303	56.754	EPSD	ICGC;COSMIC	48.822	Up-regulation
CMGC_SRPK_SRPK1_ST	Q9BWF3	RBM4	Q96SB4	SRPK1	T152	Q159H	159	Missense	distal	7	no	76.851	76.813	EPSD	ICGC;COSMIC	48.822	Down-regulation
CMGC_SRPK_SRPK1_ST	Q9BWF3	RBM4	Q96SB4	SRPK1	T152	R149W	149	Missense	distal	-3	no	76.851	36.372	EPSD	ICGC;COSMIC	48.822	Loss
CMGC_SRPK_SRPK1_ST	Q9BWF3	RBM4	Q96SB4	SRPK1	T152	A153V	153	Missense	proximal	1	no	76.851	76.610	EPSD	ICGC;COSMIC	48.822	Down-regulation
CMGC_SRPK_SRPK1_ST	Q9BWF3	RBM4	Q96SB4	SRPK1	T152	G155W	155	Missense	distal	3	no	76.851	75.218	EPSD	ICGC;COSMIC	48.822	Down-regulation
CMGC_SRPK_SRPK1_ST	Q9BWF3	RBM4	Q96SB4	SRPK1	T152	R149L	149	Missense	distal	-3	no	76.851	34.810	EPSD	ICGC	48.822	Loss
CMGC_SRPK_SRPK1_ST	Q9BWF3	RBM4	Q96SB4	SRPK1	T152	L145F	145	Missense	distal	-7	no	76.851	78.079	EPSD	ICGC	48.822	Up-regulation
CMGC_SRPK_SRPK1_ST	Q9BWF3	RBM4	Q96SB4	SRPK1	T152	S146F	146	Missense	distal	-6	no	76.851	69.654	EPSD	ICGC;COSMIC	48.822	Down-regulation
CMGC_SRPK_SRPK1_ST	Q9BWF3	RBM4	Q96SB4	SRPK1	T152	A153T	153	Missense	proximal	1	no	76.851	77.779	EPSD	ICGC;COSMIC	48.822	Up-regulation
CMGC_SRPK_SRPK1_ST	Q9BWF3	RBM4	Q96SB4	SRPK1	S160	Q159H	159	Missense	proximal	-1	no	51.916	51.722	EPSD	ICGC;COSMIC	48.822	Down-regulation
CMGC_SRPK_SRPK1_ST	Q9BWF3	RBM4	Q96SB4	SRPK1	S160	A153V	153	Missense	distal	-7	no	51.916	51.779	EPSD	ICGC;COSMIC	48.822	Down-regulation
CMGC_SRPK_SRPK1_ST	Q9BWF3	RBM4	Q96SB4	SRPK1	S160	G155W	155	Missense	distal	-5	no	51.916	51.096	EPSD	ICGC;COSMIC	48.822	Down-regulation
CMGC_SRPK_SRPK1_ST	Q9BWF3	RBM4	Q96SB4	SRPK1	S160	R164L	164	Missense	distal	4	no	51.916	47.633	EPSD	ICGC	48.822	Loss
CMGC_SRPK_SRPK1_ST	Q9BWF3	RBM4	Q96SB4	SRPK1	S160	A153T	153	Missense	distal	-7	no	51.916	52.855	EPSD	ICGC;COSMIC	48.822	Up-regulation
CMGC_SRPK_SRPK1_ST	Q9BWF3	RBM4	Q96SB4	SRPK1	S160	R164W	164	Missense	distal	4	no	51.916	47.808	EPSD	ICGC;COSMIC	48.822	Loss
CMGC_SRPK_SRPK1_ST	Q9BWF3	RBM4	Q96SB4	SRPK1	S309	G305R	305	Missense	distal	-4	no	96.030	97.624	PhosphoSitePlus	ICGC;COSMIC	48.822	Up-regulation
CMGC_SRPK_SRPK1_ST	Q9BWF3	RBM4	Q96SB4	SRPK1	S309	R313G	313	Missense	distal	4	no	96.030	92.919	PhosphoSitePlus	ICGC;COSMIC	48.822	Down-regulation
CMGC_SRPK_SRPK1_ST	Q9BWF3	RBM4	Q96SB4	SRPK1	T315	R313G	313	Missense	proximal	-2	no	79.940	76.865	EPSD	ICGC;COSMIC	48.822	Down-regulation
CMGC_SRPK_SRPK1_ST	Q9Y5S9	RBM8A	Q96SB4	SRPK1	S166	R164T	164	Missense	proximal	-2	no	184.253	177.503	EPSD;PhosphoSitePlus	ICGC	48.822	Down-regulation
CMGC_SRPK_SRPK1_ST	Q9Y5S9	RBM8A	Q96SB4	SRPK1	S166	R167S	167	Missense	proximal	1	no	184.253	168.323	EPSD;PhosphoSitePlus	ICGC;COSMIC	48.822	Down-regulation
CMGC_SRPK_SRPK1_ST	Q9Y5S9	RBM8A	Q96SB4	SRPK1	S168	R164T	164	Missense	distal	-4	no	189.678	185.298	PhosphoSitePlus;EPSD	ICGC	48.822	Down-regulation
CMGC_SRPK_SRPK1_ST	Q9Y5S9	RBM8A	Q96SB4	SRPK1	S168	R167S	167	Missense	proximal	-1	no	189.678	161.800	PhosphoSitePlus;EPSD	ICGC;COSMIC	48.822	Down-regulation
AGC_PKC_PKCi_PRKCZ_ST	Q9Y6Q9	NCOA3	Q05513	PRKCZ	S13	N7S	7	Missense	distal	-6	no	33.562	33.555	EPSD	ICGC;COSMIC	31.494	Down-regulation
AGC_PKC_PKCi_PRKCZ_ST	Q9Y6Q9	NCOA3	Q05513	PRKCZ	S13	R16Q	16	Missense	distal	3	no	33.562	27.965	EPSD	ICGC;COSMIC	31.494	Loss
AGC_PKC_PKCi_PRKCZ_ST	Q9Y6Q9	NCOA3	Q05513	PRKCZ	S101	V100A	100	Missense	proximal	-1	no	44.264	45.189	EPSD	ICGC;COSMIC	31.494	Up-regulation
AGC_PKC_PKCi_PRKCZ_ST	Q9Y6Q9	NCOA3	Q05513	PRKCZ	S101	Q105H	105	Missense	distal	4	no	44.264	43.104	EPSD	ICGC	31.494	Down-regulation
AGC_PKC_PKCi_PRKCZ_ST	Q9Y6Q9	NCOA3	Q05513	PRKCZ	S101	V100G	100	Missense	proximal	-1	no	44.264	45.144	EPSD	ICGC	31.494	Up-regulation
AGC_PKC_PKCi_PRKCZ_ST	Q9Y6Q9	NCOA3	Q05513	PRKCZ	S284	D281Y	281	Missense	distal	-3	no	32.993	32.119	EPSD	ICGC;COSMIC	31.494	Down-regulation
AGC_PKC_PKCi_PRKCZ_ST	Q9Y6Q9	NCOA3	Q05513	PRKCZ	S306	N308S	308	Missense	proximal	2	no	39.116	38.989	EPSD	ICGC;COSMIC	31.494	Down-regulation
AGC_PKC_PKCi_PRKCZ_ST	Q9Y6Q9	NCOA3	Q05513	PRKCZ	S1033	S1033Y	1033	Missense	central	0	yes	35.139	0.000	EPSD;PhosphoSitePlus	ICGC;COSMIC	31.494	Loss
AGC_PKC_PKCi_PRKCZ_ST	Q9Y6Q9	NCOA3	Q05513	PRKCZ	S1062	L1069P	1069	Missense	distal	7	no	41.445	43.974	EPSD;PhosphoSitePlus	ICGC;COSMIC	31.494	Up-regulation
AGC_PKC_PKCi_PRKCZ_ST	Q9Y6Q9	NCOA3	Q05513	PRKCZ	T1067	L1069P	1069	Missense	proximal	2	no	34.523	29.446	EPSD;PhosphoSitePlus	ICGC;COSMIC	31.494	Loss
AGC_PKC_PKCi_PRKCZ_ST	Q16625	OCLN	Q05513	PRKCZ	T403	H397Y	397	Missense	distal	-6	no	36.867	37.127	EPSD;PhosphoSitePlus	ICGC	31.494	Up-regulation
AGC_PKC_PKCi_PRKCZ_ST	Q16625	OCLN	Q05513	PRKCZ	T403	Y398F	398	Missense	distal	-5	no	36.867	37.437	EPSD;PhosphoSitePlus	ICGC	31.494	Up-regulation
AGC_PKC_PKCi_PRKCZ_ST	Q7KZI7	MARK2	Q05513	PRKCZ	S30	S32F	32	Missense	proximal	2	no	33.883	32.832	EPSD	ICGC;COSMIC	31.494	Down-regulation
AGC_PKC_PKCi_PRKCZ_ST	Q7KZI7	MARK2	Q05513	PRKCZ	S30	R36Q	36	Missense	distal	6	no	33.883	27.990	EPSD	ICGC	31.494	Loss
AGC_PKC_PKCi_PRKCZ_ST	Q7KZI7	MARK2	Q05513	PRKCZ	S43	R36Q	36	Missense	distal	-7	no	35.026	31.313	EPSD	ICGC	31.494	Loss
AGC_PKC_PKCi_PRKCZ_ST	Q7KZI7	MARK2	Q05513	PRKCZ	T294	K300Q	300	Missense	distal	6	no	44.382	41.769	EPSD	ICGC;COSMIC	31.494	Down-regulation
AGC_PKC_PKCi_PRKCZ_ST	Q7KZI7	MARK2	Q05513	PRKCZ	S648	R653L	653	Missense	distal	5	no	44.027	43.375	EPSD	ICGC;COSMIC	31.494	Down-regulation
AGC_PKC_PKCi_PRKCZ_ST	Q7KZI7	MARK2	Q05513	PRKCZ	S648	R653W	653	Missense	distal	5	no	44.027	43.201	EPSD	ICGC;COSMIC	31.494	Down-regulation
AGC_PKC_PKCi_PRKCZ_ST	P10636	MAPT	Q05513	PRKCZ	S171	R164T	164	Missense	distal	-7	no	39.858	35.505	EPSD	ICGC;COSMIC	31.494	Down-regulation
AGC_PKC_PKCi_PRKCZ_ST	P10636	MAPT	Q05513	PRKCZ	S171	A166T	166	Missense	distal	-5	no	39.858	41.201	EPSD	ICGC	31.494	Up-regulation
AGC_PKC_PKCi_PRKCZ_ST	P10636	MAPT	Q05513	PRKCZ	S341	T346I	346	Missense	distal	5	no	32.156	32.370	EPSD	ICGC;COSMIC	31.494	Up-regulation
AGC_PKC_PKCi_PRKCZ_ST	P10636	MAPT	Q05513	PRKCZ	S341	A337V	337	Missense	distal	-4	no	32.156	32.576	EPSD	ICGC	31.494	Up-regulation
AGC_PKC_PKCi_PRKCZ_ST	P10636	MAPT	Q05513	PRKCZ	S341	D345E	345	Missense	distal	4	no	32.156	34.715	EPSD	ICGC;COSMIC	31.494	Up-regulation
AGC_PKC_PKCi_PRKCZ_ST	P10636	MAPT	Q05513	PRKCZ	S447	Y441H	441	Missense	distal	-6	no	43.476	43.216	EPSD	ICGC;COSMIC	31.494	Down-regulation
AGC_PKC_PKCi_PRKCZ_ST	P61587	RND3	Q05513	PRKCZ	S7	S14Y	14	Missense	distal	7	no	56.159	58.522	EPSD	ICGC	31.494	Up-regulation
AGC_PKC_PKCi_PRKCZ_ST	P61587	RND3	Q05513	PRKCZ	S7	Q8K	8	Missense	proximal	1	no	56.159	56.784	EPSD	ICGC	31.494	Up-regulation
AGC_PKC_PKCi_PRKCZ_ST	P61587	RND3	Q05513	PRKCZ	S7	E3K	3	Missense	distal	-4	no	56.159	55.829	EPSD	ICGC;COSMIC	31.494	Down-regulation
AGC_PKC_PKCi_PRKCZ_ST	P61587	RND3	Q05513	PRKCZ	S7	L10M	10	Missense	distal	3	no	56.159	57.267	EPSD	ICGC;COSMIC	31.494	Up-regulation
AGC_PKC_PKCi_PRKCZ_ST	P61587	RND3	Q05513	PRKCZ	S11	S14Y	14	Missense	distal	3	no	40.007	37.579	EPSD	ICGC	31.494	Down-regulation
AGC_PKC_PKCi_PRKCZ_ST	P61587	RND3	Q05513	PRKCZ	S11	Q8K	8	Missense	distal	-3	no	40.007	46.756	EPSD	ICGC	31.494	Up-regulation
AGC_PKC_PKCi_PRKCZ_ST	P61587	RND3	Q05513	PRKCZ	S11	L10M	10	Missense	proximal	-1	no	40.007	41.021	EPSD	ICGC;COSMIC	31.494	Up-regulation
AGC_PKC_PKCi_PRKCZ_ST	P61587	RND3	Q05513	PRKCZ	S12	S14Y	14	Missense	proximal	2	no	39.179	39.189	EPSD	ICGC	31.494	Up-regulation
AGC_PKC_PKCi_PRKCZ_ST	P61587	RND3	Q05513	PRKCZ	S12	Q8K	8	Missense	distal	-4	no	39.179	39.095	EPSD	ICGC	31.494	Down-regulation
AGC_PKC_PKCi_PRKCZ_ST	P61587	RND3	Q05513	PRKCZ	S12	L10M	10	Missense	proximal	-2	no	39.179	41.331	EPSD	ICGC;COSMIC	31.494	Up-regulation
AGC_PKC_PKCi_PRKCZ_ST	O43175	PHGDH	Q05513	PRKCZ	T57	R54C	54	Missense	distal	-3	no	36.729	16.695	EPSD;PhosphoSitePlus	ICGC	31.494	Loss
AGC_PKC_PKCi_PRKCZ_ST	O43175	PHGDH	Q05513	PRKCZ	T78	A76S	76	Missense	proximal	-2	no	41.967	39.937	EPSD;PhosphoSitePlus	ICGC;COSMIC	31.494	Down-regulation
AGC_PKC_PKCi_PRKCZ_ST	O43175	PHGDH	Q05513	PRKCZ	S166	V160A	160	Missense	distal	-6	no	34.088	33.724	EPSD	ICGC;COSMIC	31.494	Down-regulation
AGC_PKC_PKCi_PRKCZ_ST	O43175	PHGDH	Q05513	PRKCZ	S166	S166Y	166	Missense	central	0	yes	34.088	0.000	EPSD	ICGC	31.494	Loss
AGC_PKC_PKCi_PRKCZ_ST	O43175	PHGDH	Q05513	PRKCZ	T288	H283N	283	Missense	distal	-5	no	32.755	32.344	EPSD	ICGC;COSMIC	31.494	Down-regulation
AGC_PKC_PKCi_PRKCZ_ST	P53004	BLVRA	Q05513	PRKCZ	S21	R28W	28	Missense	distal	7	no	38.923	42.053	EPSD	ICGC;COSMIC;GDSC;CCLE	31.494	Up-regulation
AGC_PKC_PKCi_PRKCZ_ST	P53004	BLVRA	Q05513	PRKCZ	S21	G15D	15	Missense	distal	-6	no	38.923	38.922	EPSD	ICGC;COSMIC	31.494	Down-regulation
AGC_PKC_PKCi_PRKCZ_ST	P53004	BLVRA	Q05513	PRKCZ	S21	G15V	15	Missense	distal	-6	no	38.923	39.056	EPSD	ICGC	31.494	Up-regulation
AGC_PKC_PKCi_PRKCZ_ST	P49841	GSK3B	Q05513	PRKCZ	S9	A11S	11	Missense	proximal	2	no	36.187	33.486	EPSD;PhosphoSitePlus	ICGC;COSMIC	31.494	Down-regulation
AGC_PKC_PKCi_PRKCZ_ST	P49841	GSK3B	Q05513	PRKCZ	S29	D33E	33	Missense	distal	4	no	40.769	43.329	EPSD	ICGC	31.494	Up-regulation
AGC_PKC_PKCi_PRKCZ_ST	P49841	GSK3B	Q05513	PRKCZ	S55	E53K	53	Missense	proximal	-2	no	22.668	32.561	EPSD	ICGC;COSMIC	31.494	Gain
AGC_PKC_PKCi_PRKCZ_ST	P49841	GSK3B	Q05513	PRKCZ	S147	P154H	154	Missense	distal	7	no	42.594	38.788	PhosphoSitePlus;EPSD	ICGC;COSMIC	31.494	Down-regulation
AGC_PKC_PKCi_PRKCZ_ST	P49841	GSK3B	Q05513	PRKCZ	S147	A149D	149	Missense	proximal	2	no	42.594	45.970	PhosphoSitePlus;EPSD	ICGC	31.494	Up-regulation
AGC_PKC_PKCi_PRKCZ_ST	P49841	GSK3B	Q05513	PRKCZ	S147	T152R	152	Missense	distal	5	no	42.594	43.171	PhosphoSitePlus;EPSD	ICGC;COSMIC	31.494	Up-regulation
AGC_PKC_PKCi_PRKCZ_ST	P49841	GSK3B	Q05513	PRKCZ	S147	Q151R	151	Missense	distal	4	no	42.594	45.810	PhosphoSitePlus;EPSD	ICGC;COSMIC	31.494	Up-regulation
AGC_PKC_PKCi_PRKCZ_ST	P49841	GSK3B	Q05513	PRKCZ	T402	G406R	406	Missense	distal	4	no	29.529	34.958	EPSD	ICGC;COSMIC	31.494	Gain
AGC_PKC_PKCi_PRKCZ_ST	P49841	GSK3B	Q05513	PRKCZ	T408	G406R	406	Missense	proximal	-2	no	47.037	57.731	EPSD	ICGC;COSMIC	31.494	Up-regulation
AGC_PKC_PKCi_PRKCZ_ST	P49841	GSK3B	Q05513	PRKCZ	T408	S415T	415	Missense	distal	7	no	47.037	45.837	EPSD	ICGC;COSMIC	31.494	Down-regulation
AGC_PKC_PKCi_PRKCZ_ST	P49841	GSK3B	Q05513	PRKCZ	S413	G406R	406	Missense	distal	-7	no	29.398	34.073	EPSD	ICGC;COSMIC	31.494	Gain
AGC_PKC_PKCi_PRKCZ_ST	P49757	NUMB	Q05513	PRKCZ	S7	K3N	3	Missense	distal	-4	no	59.036	59.091	PhosphoSitePlus;EPSD	ICGC;COSMIC	31.494	Up-regulation
AGC_PKC_PKCi_PRKCZ_ST	P49757	NUMB	Q05513	PRKCZ	S276	L283I	283	Missense	distal	7	no	32.914	34.931	EPSD	ICGC;COSMIC	31.494	Up-regulation
AGC_PKC_PKCi_PRKCZ_ST	P49757	NUMB	Q05513	PRKCZ	S295	S295Y	295	Missense	central	0	yes	34.788	0.000	EPSD	ICGC	31.494	Loss
AGC_PKC_PKCi_PRKCZ_ST	Q15831	STK11	Q05513	PRKCZ	S299	R297S	297	Missense	proximal	-2	no	45.940	33.849	EPSD	ICGC;COSMIC	31.494	Down-regulation
AGC_PKC_PKCi_PRKCZ_ST	Q15831	STK11	Q05513	PRKCZ	S299	E293V	293	Missense	distal	-6	no	45.940	45.866	EPSD	ICGC	31.494	Down-regulation
AGC_PKC_PKCi_PRKCZ_ST	Q15831	STK11	Q05513	PRKCZ	S307	W308L	308	Missense	proximal	1	no	48.975	50.343	EPSD;PhosphoSitePlus	ICGC;COSMIC	31.494	Up-regulation
AGC_PKC_PKCi_PRKCZ_ST	Q15831	STK11	Q05513	PRKCZ	S404	A397G	397	Missense	distal	-7	no	33.539	31.089	EPSD	ICGC;COSMIC	31.494	Loss
AGC_PKC_PKCi_PRKCZ_ST	Q15831	STK11	Q05513	PRKCZ	S428	R425L	425	Missense	distal	-3	no	55.503	43.186	EPSD;PhosphoSitePlus	ICGC	31.494	Down-regulation
AGC_PKC_PKCi_PRKCZ_ST	O43315	AQP9	Q05513	PRKCZ	S11	G5V	5	Missense	distal	-6	no	36.903	37.036	EPSD;PhosphoSitePlus	ICGC	31.494	Up-regulation
AGC_PKC_PKCi_PRKCZ_ST	O43315	AQP9	Q05513	PRKCZ	S11	F12L	12	Missense	proximal	1	no	36.903	35.959	EPSD;PhosphoSitePlus	ICGC;COSMIC	31.494	Down-regulation
AGC_PKC_PKCi_PRKCZ_ST	O43315	AQP9	Q05513	PRKCZ	S20	E25K	25	Missense	distal	5	no	32.078	32.340	EPSD	ICGC	31.494	Up-regulation
AGC_PKC_PKCi_PRKCZ_ST	O43315	AQP9	Q05513	PRKCZ	S21	E25K	25	Missense	distal	4	no	44.259	45.926	EPSD	ICGC	31.494	Up-regulation
AGC_PKC_PKCi_PRKCZ_ST	O43315	AQP9	Q05513	PRKCZ	S222	M215I	215	Missense	distal	-7	no	50.080	45.783	PhosphoSitePlus;EPSD	ICGC	31.494	Down-regulation
AGC_PKC_PKCi_PRKCZ_ST	O43315	AQP9	Q05513	PRKCZ	S222	P223H	223	Missense	proximal	1	no	50.080	50.789	PhosphoSitePlus;EPSD	ICGC;COSMIC	31.494	Up-regulation
AGC_PKC_PKCi_PRKCZ_ST	P35580	MYH10	Q05513	PRKCZ	S201	S201L	201	Missense	central	0	yes	35.045	0.000	EPSD	ICGC	31.494	Loss
AGC_PKC_PKCi_PRKCZ_ST	P35580	MYH10	Q05513	PRKCZ	S1487	E1493K	1493	Missense	distal	6	no	34.944	36.436	EPSD	ICGC	31.494	Up-regulation
AGC_PKC_PKCi_PRKCZ_ST	P35580	MYH10	Q05513	PRKCZ	S1487	E1482Q	1482	Missense	distal	-5	no	34.944	34.745	EPSD	ICGC;COSMIC	31.494	Down-regulation
AGC_PKC_PKCi_PRKCZ_ST	P35580	MYH10	Q05513	PRKCZ	T1582	E1585K	1585	Missense	distal	3	no	23.747	33.190	EPSD	ICGC;COSMIC	31.494	Gain
AGC_PKC_PKCi_PRKCZ_ST	P35580	MYH10	Q05513	PRKCZ	S1684	E1686K	1686	Missense	proximal	2	no	30.223	39.830	EPSD	ICGC	31.494	Gain
AGC_PKC_PKCi_PRKCZ_ST	P35580	MYH10	Q05513	PRKCZ	S1941	R1943W	1943	Missense	proximal	2	no	32.737	18.400	EPSD	ICGC;COSMIC	31.494	Loss
AGC_PKC_PKCi_PRKCZ_ST	Q9UBS0	RPS6KB2	Q05513	PRKCZ	T11	E13K	13	Missense	proximal	2	no	24.976	34.583	EPSD	ICGC	31.494	Gain
AGC_PKC_PKCi_PRKCZ_ST	Q9UBS0	RPS6KB2	Q05513	PRKCZ	S416	V422I	422	Missense	distal	6	no	48.455	47.786	EPSD	ICGC;COSMIC;CCLE	31.494	Down-regulation
AGC_PKC_PKCi_PRKCZ_ST	Q9UBS0	RPS6KB2	Q05513	PRKCZ	S416	A420V	420	Missense	distal	4	no	48.455	38.283	EPSD	ICGC;COSMIC	31.494	Down-regulation
AGC_PKC_PKCi_PRKCZ_ST	P08047	SP1	Q05513	PRKCZ	S7	S7P	7	Missense	central	0	yes	36.772	0.000	EPSD	ICGC;COSMIC	31.494	Loss
AGC_PKC_PKCi_PRKCZ_ST	P08047	SP1	Q05513	PRKCZ	S7	S7Y	7	Missense	central	0	yes	36.772	0.000	EPSD	ICGC;COSMIC	31.494	Loss
AGC_PKC_PKCi_PRKCZ_ST	P08047	SP1	Q05513	PRKCZ	S7	M11I	11	Missense	distal	4	no	36.772	32.678	EPSD	ICGC	31.494	Down-regulation
AGC_PKC_PKCi_PRKCZ_ST	P08047	SP1	Q05513	PRKCZ	S7	M8I	8	Missense	proximal	1	no	36.772	35.895	EPSD	ICGC	31.494	Down-regulation
AGC_PKC_PKCi_PRKCZ_ST	P08047	SP1	Q05513	PRKCZ	S41	S36L	36	Missense	distal	-5	no	37.171	38.686	EPSD	ICGC;COSMIC	31.494	Up-regulation
AGC_PKC_PKCi_PRKCZ_ST	P08047	SP1	Q05513	PRKCZ	S41	S46C	46	Missense	distal	5	no	37.171	37.050	EPSD	ICGC;COSMIC	31.494	Down-regulation
AGC_PKC_PKCi_PRKCZ_ST	P08047	SP1	Q05513	PRKCZ	S41	F35L	35	Missense	distal	-6	no	37.171	37.093	EPSD	ICGC;COSMIC	31.494	Down-regulation
AGC_PKC_PKCi_PRKCZ_ST	P08047	SP1	Q05513	PRKCZ	T640	C633F	633	Missense	distal	-7	no	34.592	34.129	EPSD	ICGC	31.494	Down-regulation
AGC_PKC_PKCi_PRKCZ_ST	P08047	SP1	Q05513	PRKCZ	T668	R669L	669	Missense	proximal	1	no	40.198	38.065	PhosphoSitePlus;EPSD	ICGC	31.494	Down-regulation
AGC_PKC_PKCi_PRKCZ_ST	P27448	MARK3	Q05513	PRKCZ	T211	D210Y	210	Missense	proximal	-1	no	41.358	40.427	EPSD	ICGC;COSMIC	31.494	Down-regulation
AGC_PKC_PKCi_PRKCZ_ST	P27448	MARK3	Q05513	PRKCZ	T211	D210N	210	Missense	proximal	-1	no	41.358	40.971	EPSD	ICGC;COSMIC;GDSC;CCLE	31.494	Down-regulation
AGC_PKC_PKCi_PRKCZ_ST	P27448	MARK3	Q05513	PRKCZ	T211	G207C	207	Missense	distal	-4	no	41.358	41.780	EPSD	ICGC;COSMIC	31.494	Up-regulation
AGC_PKC_PKCi_PRKCZ_ST	P27448	MARK3	Q05513	PRKCZ	T211	S215I	215	Missense	distal	4	no	41.358	34.238	EPSD	ICGC	31.494	Down-regulation
AGC_PKC_PKCi_PRKCZ_ST	P27448	MARK3	Q05513	PRKCZ	T211	G206V	206	Missense	distal	-5	no	41.358	42.533	EPSD	ICGC	31.494	Up-regulation
AGC_PKC_PKCi_PRKCZ_ST	P27448	MARK3	Q05513	PRKCZ	T297	G296D	296	Missense	proximal	-1	no	45.866	45.348	EPSD	ICGC;COSMIC	31.494	Down-regulation
AGC_PKC_PKCi_PRKCZ_ST	P27448	MARK3	Q05513	PRKCZ	S390	S390I	390	Missense	central	0	yes	32.699	0.000	EPSD	ICGC	31.494	Loss
AGC_PKC_PKCi_PRKCZ_ST	P27448	MARK3	Q05513	PRKCZ	S419	R417L	417	Missense	proximal	-2	no	44.793	33.233	EPSD	ICGC	31.494	Down-regulation
AGC_PKC_PKCi_PRKCZ_ST	P27448	MARK3	Q05513	PRKCZ	S419	G423R	423	Missense	distal	4	no	44.793	50.222	EPSD	ICGC;COSMIC	31.494	Up-regulation
AGC_PKC_PKCi_PRKCZ_ST	P27448	MARK3	Q05513	PRKCZ	S419	G423V	423	Missense	distal	4	no	44.793	39.419	EPSD	ICGC;COSMIC	31.494	Down-regulation
AGC_PKC_PKCi_PRKCZ_ST	P27448	MARK3	Q05513	PRKCZ	S419	D420N	420	Missense	proximal	1	no	44.793	44.994	EPSD	ICGC	31.494	Up-regulation
AGC_PKC_PKCi_PRKCZ_ST	P27448	MARK3	Q05513	PRKCZ	S419	R417S	417	Missense	proximal	-2	no	44.793	32.702	EPSD	ICGC	31.494	Down-regulation
AGC_PKC_PKCi_PRKCZ_ST	P27448	MARK3	Q05513	PRKCZ	S419	A422S	422	Missense	distal	3	no	44.793	38.289	EPSD	ICGC;COSMIC	31.494	Down-regulation
AGC_PKC_PKCi_PRKCZ_ST	P27448	MARK3	Q05513	PRKCZ	T438	A431S	431	Missense	distal	-7	no	39.089	36.162	EPSD	ICGC	31.494	Down-regulation
AGC_PKC_PKCi_PRKCZ_ST	P27448	MARK3	Q05513	PRKCZ	T438	S443G	443	Missense	distal	5	no	39.089	39.236	EPSD	ICGC;COSMIC	31.494	Up-regulation
AGC_PKC_PKCi_PRKCZ_ST	P27448	MARK3	Q05513	PRKCZ	S456	S451Y	451	Missense	distal	-5	no	33.771	34.214	EPSD	ICGC	31.494	Up-regulation
AGC_PKC_PKCi_PRKCZ_ST	P27448	MARK3	Q05513	PRKCZ	S456	K463E	463	Missense	distal	7	no	33.771	34.049	EPSD	ICGC;COSMIC	31.494	Up-regulation
AGC_PKC_PKCi_PRKCZ_ST	P27448	MARK3	Q05513	PRKCZ	T507	V509F	509	Missense	proximal	2	no	37.529	34.137	EPSD	ICGC	31.494	Down-regulation
AGC_PKC_PKCi_PRKCZ_ST	P27448	MARK3	Q05513	PRKCZ	T507	R504Q	504	Missense	distal	-3	no	37.529	25.642	EPSD	ICGC	31.494	Loss
AGC_PKC_PKCi_PRKCZ_ST	P27448	MARK3	Q05513	PRKCZ	T515	V509F	509	Missense	distal	-6	no	32.521	32.507	EPSD	ICGC	31.494	Down-regulation
AGC_PKC_PKCi_PRKCZ_ST	P27448	MARK3	Q05513	PRKCZ	S618	R615M	615	Missense	distal	-3	no	32.789	21.801	EPSD	ICGC;COSMIC	31.494	Loss
AGC_PKC_PKCi_PRKCZ_ST	P27448	MARK3	Q05513	PRKCZ	S643	A644G	644	Missense	proximal	1	no	36.166	36.072	EPSD	ICGC;COSMIC	31.494	Down-regulation
AGC_PKC_PKCi_PRKCZ_ST	Q96RI1	NR1H4	Q05513	PRKCZ	S164	N168S	168	Missense	distal	4	no	42.692	42.477	EPSD	ICGC;COSMIC	31.494	Down-regulation
AGC_PKC_PKCi_PRKCZ_ST	Q96A00	PPP1R14A	Q05513	PRKCZ	S12	R9C	9	Missense	distal	-3	no	45.832	25.798	EPSD	ICGC	31.494	Loss
AGC_PKC_PKCi_PRKCZ_ST	Q96A00	PPP1R14A	Q05513	PRKCZ	S16	R21C	21	Missense	distal	5	no	43.768	43.061	EPSD	ICGC;COSMIC	31.494	Down-regulation
AGC_PKC_PKCi_PRKCZ_ST	Q96A00	PPP1R14A	Q05513	PRKCZ	S16	R9C	9	Missense	distal	-7	no	43.768	37.934	EPSD	ICGC	31.494	Down-regulation
AGC_PKC_PKCi_PRKCZ_ST	Q96A00	PPP1R14A	Q05513	PRKCZ	T38	Q31K	31	Missense	distal	-7	no	42.752	46.022	PhosphoSitePlus	ICGC	31.494	Up-regulation
AGC_PKC_PKCi_PRKCZ_ST	Q96A00	PPP1R14A	Q05513	PRKCZ	T38	H34Y	34	Missense	distal	-4	no	42.752	42.866	PhosphoSitePlus	ICGC;COSMIC	31.494	Up-regulation
AGC_PKC_PKCi_PRKCZ_ST	Q96A00	PPP1R14A	Q05513	PRKCZ	T38	H34Q	34	Missense	distal	-4	no	42.752	42.722	PhosphoSitePlus	ICGC	31.494	Down-regulation
AGC_PKC_PKCi_PRKCZ_ST	Q96A00	PPP1R14A	Q05513	PRKCZ	T38	A35T	35	Missense	distal	-3	no	42.752	47.372	PhosphoSitePlus	ICGC;COSMIC	31.494	Up-regulation
AGC_PKC_PKCi_PRKCZ_ST	P35568	IRS1	Q05513	PRKCZ	S24	K23N	23	Missense	proximal	-1	no	37.310	36.450	EPSD	ICGC;COSMIC	31.494	Down-regulation
AGC_PKC_PKCi_PRKCZ_ST	P35568	IRS1	Q05513	PRKCZ	S268	R265H	265	Missense	distal	-3	no	36.016	27.588	EPSD	ICGC	31.494	Loss
AGC_PKC_PKCi_PRKCZ_ST	P35568	IRS1	Q05513	PRKCZ	S268	F264L	264	Missense	distal	-4	no	36.016	36.165	EPSD	ICGC	31.494	Up-regulation
AGC_PKC_PKCi_PRKCZ_ST	P35568	IRS1	Q05513	PRKCZ	S268	S272P	272	Missense	distal	4	no	36.016	28.980	EPSD	ICGC	31.494	Loss
AGC_PKC_PKCi_PRKCZ_ST	P35568	IRS1	Q05513	PRKCZ	S268	S268I	268	Missense	central	0	yes	36.016	0.000	EPSD	ICGC;COSMIC	31.494	Loss
AGC_PKC_PKCi_PRKCZ_ST	P35568	IRS1	Q05513	PRKCZ	S303	T300P	300	Missense	distal	-3	no	39.220	31.920	EPSD	ICGC;COSMIC;GDSC	31.494	Down-regulation
AGC_PKC_PKCi_PRKCZ_ST	P35568	IRS1	Q05513	PRKCZ	S303	V297G	297	Missense	distal	-6	no	39.220	39.087	EPSD	ICGC;COSMIC	31.494	Down-regulation
AGC_PKC_PKCi_PRKCZ_ST	P35568	IRS1	Q05513	PRKCZ	S307	T300P	300	Missense	distal	-7	no	35.352	32.712	EPSD	ICGC;COSMIC;GDSC	31.494	Down-regulation
AGC_PKC_PKCi_PRKCZ_ST	P35568	IRS1	Q05513	PRKCZ	S362	H355Q	355	Missense	distal	-7	no	36.695	36.332	EPSD	ICGC	31.494	Down-regulation
AGC_PKC_PKCi_PRKCZ_ST	P35568	IRS1	Q05513	PRKCZ	S362	L369H	369	Missense	distal	7	no	36.695	35.419	EPSD	ICGC;COSMIC	31.494	Down-regulation
AGC_PKC_PKCi_PRKCZ_ST	P35568	IRS1	Q05513	PRKCZ	S413	S412P	412	Missense	proximal	-1	no	47.563	46.707	EPSD	ICGC	31.494	Down-regulation
AGC_PKC_PKCi_PRKCZ_ST	P35568	IRS1	Q05513	PRKCZ	S413	A414D	414	Missense	proximal	1	no	47.563	47.066	EPSD	ICGC	31.494	Down-regulation
AGC_PKC_PKCi_PRKCZ_ST	P35568	IRS1	Q05513	PRKCZ	S413	R411L	411	Missense	proximal	-2	no	47.563	36.003	EPSD	ICGC;COSMIC	31.494	Down-regulation
AGC_PKC_PKCi_PRKCZ_ST	P35568	IRS1	Q05513	PRKCZ	S413	R410W	410	Missense	distal	-3	no	47.563	23.807	EPSD	ICGC	31.494	Loss
AGC_PKC_PKCi_PRKCZ_ST	P35568	IRS1	Q05513	PRKCZ	S441	D437Y	437	Missense	distal	-4	no	36.739	36.688	EPSD;PhosphoSitePlus	ICGC;COSMIC	31.494	Down-regulation
AGC_PKC_PKCi_PRKCZ_ST	P35568	IRS1	Q05513	PRKCZ	T525	S531Y	531	Missense	distal	6	no	32.377	28.139	EPSD	ICGC	31.494	Loss
AGC_PKC_PKCi_PRKCZ_ST	P35568	IRS1	Q05513	PRKCZ	S574	R572M	572	Missense	proximal	-2	no	33.848	24.441	EPSD	ICGC;COSMIC	31.494	Loss
AGC_PKC_PKCi_PRKCZ_ST	P35568	IRS1	Q05513	PRKCZ	S574	P578H	578	Missense	distal	4	no	33.848	37.735	EPSD	ICGC	31.494	Up-regulation
AGC_PKC_PKCi_PRKCZ_ST	P35568	IRS1	Q05513	PRKCZ	S574	H571N	571	Missense	distal	-3	no	33.848	29.382	EPSD	ICGC	31.494	Loss
AGC_PKC_PKCi_PRKCZ_ST	P35568	IRS1	Q05513	PRKCZ	S574	A575T	575	Missense	proximal	1	no	33.848	33.239	EPSD	ICGC;COSMIC	31.494	Down-regulation
AGC_PKC_PKCi_PRKCZ_ST	P35568	IRS1	Q05513	PRKCZ	S974	G971R	971	Missense	distal	-3	no	24.235	38.472	EPSD	ICGC;COSMIC	31.494	Gain
AGC_PKC_PKCi_PRKCZ_ST	P35568	IRS1	Q05513	PRKCZ	S1037	P1044T	1044	Missense	distal	7	no	31.965	27.456	EPSD	ICGC;COSMIC	31.494	Loss
AGC_PKC_PKCi_PRKCZ_ST	P35568	IRS1	Q05513	PRKCZ	S1100	S1106L	1106	Missense	distal	6	no	34.706	34.925	EPSD	ICGC;COSMIC	31.494	Up-regulation
AGC_PKC_PKCi_PRKCZ_ST	P35568	IRS1	Q05513	PRKCZ	S1142	D1137N	1137	Missense	distal	-5	no	38.241	37.131	EPSD	ICGC	31.494	Down-regulation
AGC_PKC_PKCi_PRKCZ_ST	P35568	IRS1	Q05513	PRKCZ	S1143	D1137N	1137	Missense	distal	-6	no	38.195	38.219	EPSD	ICGC	31.494	Up-regulation
AGC_PKC_PKCi_PRKCZ_ST	P35568	IRS1	Q05513	PRKCZ	S1218	L1211R	1211	Missense	distal	-7	no	40.982	45.741	EPSD	ICGC;COSMIC	31.494	Up-regulation
AGC_PKC_PKCi_PRKCZ_ST	P35568	IRS1	Q05513	PRKCZ	S1218	R1220H	1220	Missense	proximal	2	no	40.982	36.828	EPSD	ICGC;COSMIC	31.494	Down-regulation
AGC_PKC_PKCi_PRKCZ_ST	P35568	IRS1	Q05513	PRKCZ	S1218	T1219P	1219	Missense	proximal	1	no	40.982	41.328	EPSD	ICGC;COSMIC;GDSC	31.494	Up-regulation
AGC_PKC_PKCi_PRKCZ_ST	P35568	IRS1	Q05513	PRKCZ	T1219	R1220H	1220	Missense	proximal	1	no	41.313	40.138	EPSD	ICGC;COSMIC	31.494	Down-regulation
AGC_PKC_PKCi_PRKCZ_ST	P35568	IRS1	Q05513	PRKCZ	T1219	T1219P	1219	Missense	central	0	yes	41.313	0.000	EPSD	ICGC;COSMIC;GDSC	31.494	Loss
AGC_PKC_PKCi_PRKCZ_ST	P35568	IRS1	Q05513	PRKCZ	S1222	R1220H	1220	Missense	proximal	-2	no	41.403	32.550	EPSD	ICGC;COSMIC	31.494	Down-regulation
AGC_PKC_PKCi_PRKCZ_ST	P35568	IRS1	Q05513	PRKCZ	S1222	T1219P	1219	Missense	distal	-3	no	41.403	34.103	EPSD	ICGC;COSMIC;GDSC	31.494	Down-regulation
AGC_PKC_PKCi_PRKCZ_ST	P35568	IRS1	Q05513	PRKCZ	S1223	R1220H	1220	Missense	distal	-3	no	49.574	41.145	EPSD	ICGC;COSMIC	31.494	Down-regulation
AGC_PKC_PKCi_PRKCZ_ST	P35568	IRS1	Q05513	PRKCZ	S1223	T1219P	1219	Missense	distal	-4	no	49.574	50.159	EPSD	ICGC;COSMIC;GDSC	31.494	Up-regulation
AGC_PKC_PKCi_PRKCZ_ST	P35568	IRS1	Q05513	PRKCZ	S1227	R1220H	1220	Missense	distal	-7	no	44.292	40.941	EPSD	ICGC;COSMIC	31.494	Down-regulation
AGC_PKC_PKCi_PRKCZ_ST	Q8N2W9	PIAS4	Q05513	PRKCZ	S416	E412D	412	Missense	distal	-4	no	37.456	37.406	EPSD	ICGC;COSMIC	31.494	Down-regulation
AGC_PKC_PKCi_PRKCZ_ST	P35222	CTNNB1	Q05513	PRKCZ	S246	L252H	252	Missense	distal	6	no	29.129	32.279	EPSD	ICGC;COSMIC	31.494	Gain
AGC_PKC_PKCi_PRKCZ_ST	P35222	CTNNB1	Q05513	PRKCZ	T547	R542C	542	Missense	distal	-5	no	41.763	45.348	EPSD	ICGC;COSMIC	31.494	Up-regulation
AGC_PKC_PKCi_PRKCZ_ST	P35612	ADD2	Q05513	PRKCZ	S25	D27E	27	Missense	proximal	2	no	38.606	30.407	EPSD	ICGC	31.494	Loss
AGC_PKC_PKCi_PRKCZ_ST	P35612	ADD2	Q05513	PRKCZ	S25	D28E	28	Missense	distal	3	no	38.606	33.471	EPSD	ICGC	31.494	Down-regulation
AGC_PKC_PKCi_PRKCZ_ST	P35612	ADD2	Q05513	PRKCZ	S25	D22N	22	Missense	distal	-3	no	38.606	34.185	EPSD	ICGC;COSMIC	31.494	Down-regulation
AGC_PKC_PKCi_PRKCZ_ST	P35612	ADD2	Q05513	PRKCZ	S178	T181A	181	Missense	distal	3	no	25.484	31.693	EPSD	ICGC;COSMIC	31.494	Gain
AGC_PKC_PKCi_PRKCZ_ST	P35612	ADD2	Q05513	PRKCZ	S703	P698H	698	Missense	distal	-5	no	32.105	30.048	EPSD	ICGC;COSMIC	31.494	Loss
AGC_PKC_PKCi_PRKCZ_ST	P35612	ADD2	Q05513	PRKCZ	S713	S718I	718	Missense	distal	5	no	51.158	51.382	PhosphoSitePlus	ICGC;CCLE	31.494	Up-regulation
AGC_PKC_PKCi_PRKCZ_ST	P35612	ADD2	Q05513	PRKCZ	S718	S718I	718	Missense	central	0	yes	50.333	0.000	EPSD	ICGC;CCLE	31.494	Loss
AGC_PKC_PKCi_PRKCZ_ST	P35611	ADD1	Q05513	PRKCZ	S59	A66S	66	Missense	distal	7	no	36.987	36.589	EPSD	ICGC	31.494	Down-regulation
AGC_PKC_PKCi_PRKCZ_ST	P35611	ADD1	Q05513	PRKCZ	S59	M52I	52	Missense	distal	-7	no	36.987	32.690	EPSD	ICGC	31.494	Down-regulation
AGC_PKC_PKCi_PRKCZ_ST	P35611	ADD1	Q05513	PRKCZ	S59	V58A	58	Missense	proximal	-1	no	36.987	37.912	EPSD	ICGC;COSMIC	31.494	Up-regulation
AGC_PKC_PKCi_PRKCZ_ST	P35611	ADD1	Q05513	PRKCZ	S59	M60K	60	Missense	proximal	1	no	36.987	35.911	EPSD	ICGC;COSMIC	31.494	Down-regulation
AGC_PKC_PKCi_PRKCZ_ST	P35611	ADD1	Q05513	PRKCZ	S358	P359L	359	Missense	proximal	1	no	33.099	32.851	EPSD	ICGC;COSMIC	31.494	Down-regulation
AGC_PKC_PKCi_PRKCZ_ST	P35611	ADD1	Q05513	PRKCZ	S358	G357V	357	Missense	proximal	-1	no	33.099	32.220	EPSD	ICGC	31.494	Down-regulation
AGC_PKC_PKCi_PRKCZ_ST	P35611	ADD1	Q05513	PRKCZ	S358	G365V	365	Missense	distal	7	no	33.099	30.887	EPSD	ICGC;COSMIC	31.494	Loss
AGC_PKC_PKCi_PRKCZ_ST	P35611	ADD1	Q05513	PRKCZ	S358	P359T	359	Missense	proximal	1	no	33.099	32.753	EPSD	ICGC;COSMIC	31.494	Down-regulation
AGC_PKC_PKCi_PRKCZ_ST	P35611	ADD1	Q05513	PRKCZ	S481	D476N	476	Missense	distal	-5	no	37.015	35.905	EPSD	ICGC;COSMIC	31.494	Down-regulation
AGC_PKC_PKCi_PRKCZ_ST	P35611	ADD1	Q05513	PRKCZ	T540	E537D	537	Missense	distal	-3	no	21.580	31.539	EPSD	ICGC	31.494	Gain
AGC_PKC_PKCi_PRKCZ_ST	P35611	ADD1	Q05513	PRKCZ	S600	A606S	606	Missense	distal	6	no	34.711	33.148	EPSD	ICGC	31.494	Down-regulation
AGC_PKC_PKCi_PRKCZ_ST	P35611	ADD1	Q05513	PRKCZ	S600	P601S	601	Missense	proximal	1	no	34.711	34.157	EPSD	ICGC	31.494	Down-regulation
AGC_PKC_PKCi_PRKCZ_ST	P35611	ADD1	Q05513	PRKCZ	S600	V607A	607	Missense	distal	7	no	34.711	34.965	EPSD	ICGC	31.494	Up-regulation
AGC_PKC_PKCi_PRKCZ_ST	P35611	ADD1	Q05513	PRKCZ	S600	A606T	606	Missense	distal	6	no	34.711	31.767	EPSD	ICGC	31.494	Down-regulation
AGC_PKC_PKCi_PRKCZ_ST	P35611	ADD1	Q05513	PRKCZ	S600	D603Y	603	Missense	distal	3	no	34.711	27.821	EPSD	ICGC	31.494	Loss
AGC_PKC_PKCi_PRKCZ_ST	P35611	ADD1	Q05513	PRKCZ	S632	T627I	627	Missense	distal	-5	no	40.609	39.691	EPSD	ICGC	31.494	Down-regulation
AGC_PKC_PKCi_PRKCZ_ST	P35611	ADD1	Q05513	PRKCZ	S632	T627N	627	Missense	distal	-5	no	40.609	39.526	EPSD	ICGC;COSMIC	31.494	Down-regulation
AGC_PKC_PKCi_PRKCZ_ST	P35611	ADD1	Q05513	PRKCZ	S669	P667H	667	Missense	proximal	-2	no	29.268	34.353	EPSD	ICGC;COSMIC	31.494	Gain
AGC_PKC_PKCi_PRKCZ_ST	P35611	ADD1	Q05513	PRKCZ	S710	S714F	714	Missense	distal	4	no	34.885	22.670	EPSD	ICGC;COSMIC	31.494	Loss
AGC_PKC_PKCi_PRKCZ_ST	P35611	ADD1	Q05513	PRKCZ	S710	P711S	711	Missense	proximal	1	no	34.885	34.331	EPSD	ICGC;COSMIC	31.494	Down-regulation
AGC_PKC_PKCi_PRKCZ_ST	P35611	ADD1	Q05513	PRKCZ	S710	D708N	708	Missense	proximal	-2	no	34.885	28.807	EPSD	ICGC;COSMIC	31.494	Loss
AGC_PKC_PKCi_PRKCZ_ST	P35611	ADD1	Q05513	PRKCZ	S710	P715L	715	Missense	distal	5	no	34.885	34.797	EPSD	ICGC;COSMIC	31.494	Down-regulation
AGC_PKC_PKCi_PRKCZ_ST	P35611	ADD1	Q05513	PRKCZ	S716	R723C	723	Missense	distal	7	no	32.842	36.104	EPSD	ICGC;COSMIC	31.494	Up-regulation
AGC_PKC_PKCi_PRKCZ_ST	P35611	ADD1	Q05513	PRKCZ	S716	S714F	714	Missense	proximal	-2	no	32.842	30.625	EPSD	ICGC;COSMIC	31.494	Loss
AGC_PKC_PKCi_PRKCZ_ST	P35611	ADD1	Q05513	PRKCZ	S716	P711S	711	Missense	distal	-5	no	32.842	31.450	EPSD	ICGC;COSMIC	31.494	Loss
AGC_PKC_PKCi_PRKCZ_ST	P35611	ADD1	Q05513	PRKCZ	S716	P715L	715	Missense	proximal	-1	no	32.842	33.003	EPSD	ICGC;COSMIC	31.494	Up-regulation
AGC_PKC_PKCi_PRKCZ_ST	P35611	ADD1	Q05513	PRKCZ	S726	R723C	723	Missense	distal	-3	no	67.935	47.901	PhosphoSitePlus	ICGC;COSMIC	31.494	Down-regulation
AGC_PKC_PKCi_PRKCZ_ST	P35611	ADD1	Q05513	PRKCZ	S726	P725L	725	Missense	proximal	-1	no	67.935	68.096	PhosphoSitePlus	ICGC;COSMIC	31.494	Up-regulation
AGC_PKC_PKCi_PRKCZ_ST	P35611	ADD1	Q05513	PRKCZ	S731	P725L	725	Missense	distal	-6	no	49.943	49.691	EPSD	ICGC;COSMIC	31.494	Down-regulation
AGC_PKC_PKCi_PRKCZ_ST	Q9UJZ1	STOML2	Q05513	PRKCZ	S17	A24T	24	Missense	distal	7	no	43.322	41.725	PhosphoSitePlus	ICGC;COSMIC	31.494	Down-regulation
AGC_PKC_PKCi_PRKCZ_ST	Q9UJZ1	STOML2	Q05513	PRKCZ	S21	A24T	24	Missense	distal	3	no	37.672	31.462	EPSD	ICGC;COSMIC	31.494	Loss
AGC_PKC_PKCi_PRKCZ_ST	Q9UJZ1	STOML2	Q05513	PRKCZ	S21	P25T	25	Missense	distal	4	no	37.672	39.448	EPSD	ICGC	31.494	Up-regulation
AGC_PKC_PKCi_PRKCZ_ST	Q9UJZ1	STOML2	Q05513	PRKCZ	S29	A24T	24	Missense	distal	-5	no	32.184	33.526	EPSD	ICGC;COSMIC	31.494	Up-regulation
AGC_PKC_PKCi_PRKCZ_ST	Q9UJZ1	STOML2	Q05513	PRKCZ	S29	P25T	25	Missense	distal	-4	no	32.184	31.598	EPSD	ICGC	31.494	Down-regulation
AGC_PKC_PKCi_PRKCZ_ST	Q9UJZ1	STOML2	Q05513	PRKCZ	S29	S30P	30	Missense	proximal	1	no	32.184	32.738	EPSD	ICGC;COSMIC	31.494	Up-regulation
AGC_PKC_PKCi_PRKCZ_ST	Q9UJZ1	STOML2	Q05513	PRKCZ	S336	T342K	342	Missense	distal	6	no	29.434	31.948	EPSD	ICGC	31.494	Gain
AGC_PKC_PKCi_PRKCZ_ST	Q9UJZ1	STOML2	Q05513	PRKCZ	S345	T342K	342	Missense	distal	-3	no	39.022	45.455	EPSD	ICGC	31.494	Up-regulation
AGC_PKC_PKCi_PRKCZ_ST	Q9UJZ1	STOML2	Q05513	PRKCZ	S345	L346F	346	Missense	proximal	1	no	39.022	39.965	EPSD	ICGC	31.494	Up-regulation
AGC_PKC_PKCi_PRKCZ_ST	P55211	CASP9	Q05513	PRKCZ	S87	Q94K	94	Missense	distal	7	no	30.588	32.510	EPSD	ICGC	31.494	Gain
AGC_PKC_PKCi_PRKCZ_ST	P55211	CASP9	Q05513	PRKCZ	S144	R146S	146	Missense	proximal	2	no	47.095	37.068	PhosphoSitePlus	ICGC;COSMIC	31.494	Down-regulation
AGC_PKC_PKCi_PRKCZ_ST	P55211	CASP9	Q05513	PRKCZ	S144	G140S	140	Missense	distal	-4	no	47.095	47.155	PhosphoSitePlus	ICGC;COSMIC	31.494	Up-regulation
AGC_PKC_PKCi_PRKCZ_ST	P78563	ADARB1	Q05513	PRKCZ	S26	D23N	23	Missense	distal	-3	no	33.331	28.911	EPSD	ICGC;COSMIC	31.494	Loss
AGC_PKC_PKCi_PRKCZ_ST	P78563	ADARB1	Q05513	PRKCZ	S26	R20H	20	Missense	distal	-6	no	33.331	33.676	EPSD	ICGC;COSMIC	31.494	Up-regulation
AGC_PKC_PKCi_PRKCZ_ST	P78563	ADARB1	Q05513	PRKCZ	S26	S31I	31	Missense	distal	5	no	33.331	33.555	EPSD	ICGC	31.494	Up-regulation
AGC_PKC_PKCi_PRKCZ_ST	P78563	ADARB1	Q05513	PRKCZ	S26	T32A	32	Missense	distal	6	no	33.331	36.276	EPSD	ICGC;COSMIC	31.494	Up-regulation
AGC_PKC_PKCi_PRKCZ_ST	P78563	ADARB1	Q05513	PRKCZ	S26	G30S	30	Missense	distal	4	no	33.331	37.534	EPSD	ICGC	31.494	Up-regulation
AGC_PKC_PKCi_PRKCZ_ST	P78563	ADARB1	Q05513	PRKCZ	S31	S31I	31	Missense	central	0	yes	32.318	0.000	EPSD	ICGC	31.494	Loss
AGC_PKC_PKCi_PRKCZ_ST	P78563	ADARB1	Q05513	PRKCZ	S31	G38V	38	Missense	distal	7	no	32.318	30.106	EPSD	ICGC;COSMIC	31.494	Loss
AGC_PKC_PKCi_PRKCZ_ST	P78563	ADARB1	Q05513	PRKCZ	S31	G36C	36	Missense	distal	5	no	32.318	32.050	EPSD	ICGC	31.494	Down-regulation
AGC_PKC_PKCi_PRKCZ_ST	P78563	ADARB1	Q05513	PRKCZ	S31	T32A	32	Missense	proximal	1	no	32.318	32.928	EPSD	ICGC;COSMIC	31.494	Up-regulation
AGC_PKC_PKCi_PRKCZ_ST	P78563	ADARB1	Q05513	PRKCZ	S31	G30S	30	Missense	proximal	-1	no	32.318	31.671	EPSD	ICGC	31.494	Down-regulation
AGC_PKC_PKCi_PRKCZ_ST	P78563	ADARB1	Q05513	PRKCZ	S199	G196V	196	Missense	distal	-3	no	29.178	31.798	EPSD	ICGC;COSMIC	31.494	Gain
AGC_PKC_PKCi_PRKCZ_ST	P78563	ADARB1	Q05513	PRKCZ	S429	S429L	429	Missense	central	0	yes	36.197	0.000	EPSD	ICGC;COSMIC	31.494	Loss
AGC_PKC_PKCi_PRKCZ_ST	P78563	ADARB1	Q05513	PRKCZ	S429	R431L	431	Missense	proximal	2	no	36.197	28.730	EPSD	ICGC;COSMIC	31.494	Loss
AGC_PKC_PKCi_PRKCZ_ST	P78563	ADARB1	Q05513	PRKCZ	S429	R431Q	431	Missense	proximal	2	no	36.197	28.328	EPSD	ICGC;COSMIC	31.494	Loss
AGC_PKC_PKCi_PRKCZ_ST	Q9UIQ6	LNPEP	Q05513	PRKCZ	S336	D340H	340	Missense	distal	4	no	30.750	33.331	EPSD	ICGC;COSMIC	31.494	Gain
AGC_PKC_PKCi_PRKCZ_ST	Q9UIQ6	LNPEP	Q05513	PRKCZ	T609	W610L	610	Missense	proximal	1	no	30.151	31.519	EPSD	ICGC;COSMIC	31.494	Gain
AGC_PKC_PKCi_PRKCZ_ST	Q9UIQ6	LNPEP	Q05513	PRKCZ	T611	W610L	610	Missense	proximal	-1	no	30.851	31.580	EPSD	ICGC;COSMIC	31.494	Gain
AGC_PKC_PKCi_PRKCZ_ST	Q9UIQ6	LNPEP	Q05513	PRKCZ	S666	V659F	659	Missense	distal	-7	no	43.902	43.773	EPSD	ICGC	31.494	Down-regulation
AGC_PKC_PKCi_PRKCZ_ST	Q9UIQ6	LNPEP	Q05513	PRKCZ	S666	R663K	663	Missense	distal	-3	no	43.902	38.764	EPSD	ICGC	31.494	Down-regulation
AGC_PKC_PKCi_PRKCZ_ST	Q9UIQ6	LNPEP	Q05513	PRKCZ	T921	Q922R	922	Missense	proximal	1	no	35.854	38.127	EPSD	ICGC;COSMIC	31.494	Up-regulation
AGC_PKC_PKCi_PRKCZ_ST	Q15466	NR0B2	Q05513	PRKCZ	T55	Q48K	48	Missense	distal	-7	no	32.103	35.373	PhosphoSitePlus	ICGC	31.494	Up-regulation
AGC_PKC_PKCi_PRKCZ_ST	P28329	CHAT	Q05513	PRKCZ	S125	K118N	118	Missense	distal	-7	no	38.571	33.663	EPSD	ICGC	31.494	Down-regulation
AGC_PKC_PKCi_PRKCZ_ST	P46937	YAP1	Q05513	PRKCZ	S105	T110S	110	Missense	distal	5	no	34.124	34.115	EPSD	ICGC;COSMIC	31.494	Down-regulation
AGC_PKC_PKCi_PRKCZ_ST	P46937	YAP1	Q05513	PRKCZ	S105	P99Q	99	Missense	distal	-6	no	34.124	33.773	EPSD	ICGC;COSMIC	31.494	Down-regulation
AGC_PKC_PKCi_PRKCZ_ST	P46937	YAP1	Q05513	PRKCZ	S109	T110S	110	Missense	proximal	1	no	47.612	47.403	EPSD;PhosphoSitePlus	ICGC;COSMIC	31.494	Down-regulation
AGC_PKC_PKCi_PRKCZ_ST	P46937	YAP1	Q05513	PRKCZ	S109	A115T	115	Missense	distal	6	no	47.612	44.667	EPSD;PhosphoSitePlus	ICGC	31.494	Down-regulation
AGC_PKC_PKCi_PRKCZ_ST	P46937	YAP1	Q05513	PRKCZ	S184	S184F	184	Missense	central	0	yes	34.757	0.000	EPSD	ICGC;COSMIC	31.494	Loss
AGC_PKC_PKCi_PRKCZ_ST	P46937	YAP1	Q05513	PRKCZ	S397	L402P	402	Missense	distal	5	no	36.276	36.364	EPSD	ICGC;COSMIC	31.494	Up-regulation
AGC_PKC_PKCi_PRKCZ_ST	P46937	YAP1	Q05513	PRKCZ	S397	R394Q	394	Missense	distal	-3	no	36.276	24.389	EPSD	ICGC;COSMIC	31.494	Loss
AGC_PKC_PKCi_PRKCZ_ST	P46937	YAP1	Q05513	PRKCZ	S397	S397I	397	Missense	central	0	yes	36.276	0.000	EPSD	ICGC	31.494	Loss
AGC_PKC_PKCi_PRKCZ_ST	P46937	YAP1	Q05513	PRKCZ	S397	H392N	392	Missense	distal	-5	no	36.276	35.865	EPSD	ICGC;COSMIC	31.494	Down-regulation
AGC_PKC_PKCi_PRKCZ_ST	P46937	YAP1	Q05513	PRKCZ	S397	T398A	398	Missense	proximal	1	no	36.276	36.885	EPSD	ICGC;COSMIC	31.494	Up-regulation
AGC_PKC_PKCi_PRKCZ_ST	P46937	YAP1	Q05513	PRKCZ	S408	L402P	402	Missense	distal	-6	no	34.382	34.634	EPSD	ICGC;COSMIC	31.494	Up-regulation
AGC_PKC_PKCi_PRKCZ_ST	P46937	YAP1	Q05513	PRKCZ	S408	V409F	409	Missense	proximal	1	no	34.382	34.167	EPSD	ICGC	31.494	Down-regulation
AGC_PKC_PKCi_PRKCZ_ST	P46937	YAP1	Q05513	PRKCZ	T428	E422K	422	Missense	distal	-6	no	34.511	34.069	EPSD	ICGC;COSMIC	31.494	Down-regulation
AGC_PKC_PKCi_PRKCZ_ST	P46937	YAP1	Q05513	PRKCZ	T428	M423I	423	Missense	distal	-5	no	34.511	34.658	EPSD	ICGC	31.494	Up-regulation
AGC_PKC_PKCi_PRKCZ_ST	P46937	YAP1	Q05513	PRKCZ	T428	N430T	430	Missense	proximal	2	no	34.511	35.474	EPSD	ICGC;COSMIC	31.494	Up-regulation
AGC_PKC_PKCi_PRKCZ_ST	P46937	YAP1	Q05513	PRKCZ	S499	T493A	493	Missense	distal	-6	no	38.495	38.347	EPSD	ICGC;COSMIC	31.494	Down-regulation
AGC_PKC_PKCi_PRKCZ_ST	Q5JVS0	HABP4	Q05513	PRKCZ	T375	R376P	376	Missense	proximal	1	no	43.427	41.543	PhosphoSitePlus;EPSD	ICGC;COSMIC	31.494	Down-regulation
AGC_PKC_PKCi_PRKCZ_ST	Q8IX03	WWC1	Q05513	PRKCZ	S533	P536Q	536	Missense	distal	3	no	27.209	37.680	EPSD	ICGC;COSMIC	31.494	Gain
AGC_PKC_PKCi_PRKCZ_ST	Q8IX03	WWC1	Q05513	PRKCZ	S539	P536Q	536	Missense	distal	-3	no	25.195	32.179	EPSD	ICGC;COSMIC	31.494	Gain
AGC_PKC_PKCi_PRKCZ_ST	Q8IX03	WWC1	Q05513	PRKCZ	S793	L796P	796	Missense	distal	3	no	34.090	26.242	EPSD	ICGC;COSMIC	31.494	Loss
AGC_PKC_PKCi_PRKCZ_ST	Q8IX03	WWC1	Q05513	PRKCZ	S793	K791R	791	Missense	proximal	-2	no	34.090	39.315	EPSD	ICGC	31.494	Up-regulation
AGC_PKC_PKCi_PRKCZ_ST	Q8IX03	WWC1	Q05513	PRKCZ	S962	S962F	962	Missense	central	0	yes	43.096	0.000	EPSD	ICGC	31.494	Loss
AGC_PKC_PKCi_PRKCZ_ST	Q8IX03	WWC1	Q05513	PRKCZ	S974	S975L	975	Missense	proximal	1	no	37.061	37.367	EPSD	ICGC;COSMIC	31.494	Up-regulation
AGC_PKC_PKCi_PRKCZ_ST	Q8IX03	WWC1	Q05513	PRKCZ	S974	R980H	980	Missense	distal	6	no	37.061	36.018	EPSD	ICGC;COSMIC	31.494	Down-regulation
AGC_PKC_PKCi_PRKCZ_ST	Q8IX03	WWC1	Q05513	PRKCZ	S974	P973L	973	Missense	proximal	-1	no	37.061	37.221	EPSD	ICGC;COSMIC	31.494	Up-regulation
AGC_PKC_PKCi_PRKCZ_ST	Q8IX03	WWC1	Q05513	PRKCZ	S974	R980C	980	Missense	distal	6	no	37.061	30.050	EPSD	ICGC;COSMIC	31.494	Loss
AGC_PKC_PKCi_PRKCZ_ST	Q8IX03	WWC1	Q05513	PRKCZ	S974	S981C	981	Missense	distal	7	no	37.061	40.367	EPSD	ICGC;COSMIC	31.494	Up-regulation
AGC_PKC_PKCi_PRKCZ_ST	Q8IX03	WWC1	Q05513	PRKCZ	S974	P973S	973	Missense	proximal	-1	no	37.061	37.917	EPSD	ICGC;COSMIC	31.494	Up-regulation
AGC_PKC_PKCi_PRKCZ_ST	Q8IX03	WWC1	Q05513	PRKCZ	S978	S975L	975	Missense	distal	-3	no	37.486	38.595	PhosphoSitePlus;EPSD	ICGC;COSMIC	31.494	Up-regulation
AGC_PKC_PKCi_PRKCZ_ST	Q8IX03	WWC1	Q05513	PRKCZ	S978	R983C	983	Missense	distal	5	no	37.486	36.780	PhosphoSitePlus;EPSD	ICGC;COSMIC	31.494	Down-regulation
AGC_PKC_PKCi_PRKCZ_ST	Q8IX03	WWC1	Q05513	PRKCZ	S978	R980H	980	Missense	proximal	2	no	37.486	33.333	PhosphoSitePlus;EPSD	ICGC;COSMIC	31.494	Down-regulation
AGC_PKC_PKCi_PRKCZ_ST	Q8IX03	WWC1	Q05513	PRKCZ	S978	P973L	973	Missense	distal	-5	no	37.486	37.609	PhosphoSitePlus;EPSD	ICGC;COSMIC	31.494	Up-regulation
AGC_PKC_PKCi_PRKCZ_ST	Q8IX03	WWC1	Q05513	PRKCZ	S978	E982K	982	Missense	distal	4	no	37.486	39.153	PhosphoSitePlus;EPSD	ICGC;COSMIC	31.494	Up-regulation
AGC_PKC_PKCi_PRKCZ_ST	Q8IX03	WWC1	Q05513	PRKCZ	S978	R980C	980	Missense	proximal	2	no	37.486	26.297	PhosphoSitePlus;EPSD	ICGC;COSMIC	31.494	Loss
AGC_PKC_PKCi_PRKCZ_ST	Q8IX03	WWC1	Q05513	PRKCZ	S978	S981C	981	Missense	distal	3	no	37.486	31.924	PhosphoSitePlus;EPSD	ICGC;COSMIC	31.494	Down-regulation
AGC_PKC_PKCi_PRKCZ_ST	Q8IX03	WWC1	Q05513	PRKCZ	S978	R983P	983	Missense	distal	5	no	37.486	36.922	PhosphoSitePlus;EPSD	ICGC;COSMIC	31.494	Down-regulation
AGC_PKC_PKCi_PRKCZ_ST	Q8IX03	WWC1	Q05513	PRKCZ	S978	R983H	983	Missense	distal	5	no	37.486	37.077	PhosphoSitePlus;EPSD	ICGC;COSMIC	31.494	Down-regulation
AGC_PKC_PKCi_PRKCZ_ST	Q8IX03	WWC1	Q05513	PRKCZ	S978	P973S	973	Missense	distal	-5	no	37.486	36.094	PhosphoSitePlus;EPSD	ICGC;COSMIC	31.494	Down-regulation
AGC_PKC_PKCi_PRKCZ_ST	Q16612	NREP	Q05513	PRKCZ	S59	R58C	58	Missense	proximal	-1	no	36.358	34.420	PhosphoSitePlus	ICGC;COSMIC	31.494	Down-regulation
AGC_PKC_PKCi_PRKCZ_ST	Q16612	NREP	Q05513	PRKCZ	S59	R58L	58	Missense	proximal	-1	no	36.358	34.561	PhosphoSitePlus	ICGC	31.494	Down-regulation
AGC_PKC_PKCi_PRKCZ_ST	Q16612	NREP	Q05513	PRKCZ	S59	G53S	53	Missense	distal	-6	no	36.358	36.373	PhosphoSitePlus	ICGC;COSMIC	31.494	Up-regulation
AGC_PKC_PKCi_PRKCZ_ST	Q16612	NREP	Q05513	PRKCZ	S59	R61K	61	Missense	proximal	2	no	36.358	33.816	PhosphoSitePlus	ICGC	31.494	Down-regulation
AGC_PKC_PKCi_PRKCZ_ST	Q16612	NREP	Q05513	PRKCZ	S59	R61I	61	Missense	proximal	2	no	36.358	23.711	PhosphoSitePlus	ICGC;COSMIC	31.494	Loss
AGC_PKC_PKCi_PRKCZ_ST	Q16612	NREP	Q05513	PRKCZ	S59	G53D	53	Missense	distal	-6	no	36.358	36.357	PhosphoSitePlus	ICGC	31.494	Down-regulation
AGC_PKC_PKCi_PRKCZ_ST	P55040	GEM	Q05513	PRKCZ	T12	Q16K	16	Missense	distal	4	no	39.531	40.016	EPSD	ICGC	31.494	Up-regulation
AGC_PKC_PKCi_PRKCZ_ST	P55040	GEM	Q05513	PRKCZ	T12	R9S	9	Missense	distal	-3	no	39.531	26.105	EPSD	ICGC	31.494	Loss
AGC_PKC_PKCi_PRKCZ_ST	P55040	GEM	Q05513	PRKCZ	T49	R45C	45	Missense	distal	-4	no	31.274	31.936	EPSD	ICGC;COSMIC	31.494	Gain
AGC_PKC_PKCi_PRKCZ_ST	P55040	GEM	Q05513	PRKCZ	T49	R43G	43	Missense	distal	-6	no	31.274	31.731	EPSD	ICGC	31.494	Gain
AGC_PKC_PKCi_PRKCZ_ST	P55040	GEM	Q05513	PRKCZ	T49	N44K	44	Missense	distal	-5	no	31.274	32.246	EPSD	ICGC	31.494	Gain
AGC_PKC_PKCi_PRKCZ_ST	P55040	GEM	Q05513	PRKCZ	S261	R268C	268	Missense	distal	7	no	45.568	48.831	PhosphoSitePlus	ICGC;COSMIC	31.494	Up-regulation
AGC_PKC_PKCi_PRKCZ_ST	P55040	GEM	Q05513	PRKCZ	S261	P263H	263	Missense	proximal	2	no	45.568	53.959	PhosphoSitePlus	ICGC	31.494	Up-regulation
AGC_PKC_PKCi_PRKCZ_ST	P55040	GEM	Q05513	PRKCZ	S287	S287Y	287	Missense	central	0	yes	32.483	0.000	EPSD	ICGC	31.494	Loss
AGC_PKC_PKCi_PRKCZ_ST	P55040	GEM	Q05513	PRKCZ	S289	S287Y	287	Missense	proximal	-2	no	41.537	42.007	EPSD	ICGC	31.494	Up-regulation
AGC_PKC_PKCi_PRKCZ_ST	Q12933	TRAF2	Q05513	PRKCZ	S55	C49F	49	Missense	distal	-6	no	34.062	34.029	PhosphoSitePlus	ICGC	31.494	Down-regulation
AGC_PKC_PKCi_PRKCZ_ST	Q12933	TRAF2	Q05513	PRKCZ	S162	P157L	157	Missense	distal	-5	no	37.114	37.237	EPSD	ICGC;COSMIC	31.494	Up-regulation
AGC_PKC_PKCi_PRKCZ_ST	Q12933	TRAF2	Q05513	PRKCZ	S162	E158K	158	Missense	distal	-4	no	37.114	36.784	EPSD	ICGC;COSMIC	31.494	Down-regulation
AGC_PKC_PKCi_PRKCZ_ST	Q12933	TRAF2	Q05513	PRKCZ	S162	R167Q	167	Missense	distal	5	no	37.114	36.487	EPSD	ICGC	31.494	Down-regulation
AGC_PKC_PKCi_PRKCZ_ST	Q12933	TRAF2	Q05513	PRKCZ	S262	A264V	264	Missense	proximal	2	no	33.818	33.457	EPSD	ICGC	31.494	Down-regulation
AGC_PKC_PKCi_PRKCZ_ST	Q12933	TRAF2	Q05513	PRKCZ	S262	S266L	266	Missense	distal	4	no	33.818	22.995	EPSD	ICGC;COSMIC	31.494	Loss
AGC_PKC_PKCi_PRKCZ_ST	Q12933	TRAF2	Q05513	PRKCZ	S262	A264S	264	Missense	proximal	2	no	33.818	31.117	EPSD	ICGC	31.494	Loss
AGC_PKC_PKCi_PRKCZ_ST	Q12933	TRAF2	Q05513	PRKCZ	S262	L268F	268	Missense	distal	6	no	33.818	29.396	EPSD	ICGC;COSMIC	31.494	Loss
AGC_PKC_PKCi_PRKCZ_ST	Q12933	TRAF2	Q05513	PRKCZ	S274	L268F	268	Missense	distal	-6	no	37.917	37.995	EPSD	ICGC;COSMIC	31.494	Up-regulation
AGC_PKC_PKCi_PRKCZ_ST	P14598	NCF1	Q05513	PRKCZ	T45	E46K	46	Missense	proximal	1	no	31.345	33.287	EPSD	ICGC	31.494	Gain
AGC_PKC_PKCi_PRKCZ_ST	Q04206	RELA	Q05513	PRKCZ	S131	R133C	133	Missense	proximal	2	no	36.152	24.963	EPSD	ICGC	31.494	Loss
AGC_PKC_PKCi_PRKCZ_ST	Q04206	RELA	Q05513	PRKCZ	S131	D125E	125	Missense	distal	-6	no	36.152	36.360	EPSD	ICGC	31.494	Up-regulation
AGC_PKC_PKCi_PRKCZ_ST	Q04206	RELA	Q05513	PRKCZ	S131	E127Q	127	Missense	distal	-4	no	36.152	35.907	EPSD	ICGC;COSMIC	31.494	Down-regulation
AGC_PKC_PKCi_PRKCZ_ST	Q04206	RELA	Q05513	PRKCZ	S238	A235S	235	Missense	distal	-3	no	40.708	43.473	EPSD	ICGC;COSMIC	31.494	Up-regulation
AGC_PKC_PKCi_PRKCZ_ST	Q04206	RELA	Q05513	PRKCZ	S238	R236Q	236	Missense	proximal	-2	no	40.708	30.722	EPSD	ICGC;COSMIC	31.494	Loss
AGC_PKC_PKCi_PRKCZ_ST	Q04206	RELA	Q05513	PRKCZ	S238	E234V	234	Missense	distal	-4	no	40.708	40.763	EPSD	ICGC	31.494	Up-regulation
AGC_PKC_PKCi_PRKCZ_ST	Q04206	RELA	Q05513	PRKCZ	S276	D277E	277	Missense	proximal	1	no	44.397	42.925	EPSD	ICGC;COSMIC	31.494	Down-regulation
AGC_PKC_PKCi_PRKCZ_ST	Q04206	RELA	Q05513	PRKCZ	S311	P317H	317	Missense	distal	6	no	37.373	42.456	PhosphoSitePlus	ICGC;COSMIC	31.494	Up-regulation
AGC_PKC_PKCi_PRKCZ_ST	Q04206	RELA	Q05513	PRKCZ	S311	S311G	311	Missense	central	0	yes	37.373	0.000	PhosphoSitePlus	ICGC;COSMIC	31.494	Loss
AGC_PKC_PKCi_PRKCZ_ST	Q04206	RELA	Q05513	PRKCZ	S468	D470E	470	Missense	proximal	2	no	33.736	25.537	EPSD	ICGC	31.494	Loss
AGC_PKC_PKCi_PRKCZ_ST	Q04206	RELA	Q05513	PRKCZ	T505	P510S	510	Missense	distal	5	no	44.864	44.842	EPSD	ICGC;COSMIC	31.494	Down-regulation
AGC_PKC_PKCi_PRKCZ_ST	Q04206	RELA	Q05513	PRKCZ	T505	P511T	511	Missense	distal	6	no	44.864	45.195	EPSD	ICGC	31.494	Up-regulation
AGC_PKC_PKCi_PRKCZ_ST	Q04206	RELA	Q05513	PRKCZ	T505	T505K	505	Missense	central	0	yes	44.864	0.000	EPSD	ICGC	31.494	Loss
AGC_PKC_PKCi_PRKCZ_ST	Q04206	RELA	Q05513	PRKCZ	S536	A538V	538	Missense	proximal	2	no	42.930	42.569	EPSD	ICGC;COSMIC	31.494	Down-regulation
AGC_PKC_PKCi_PRKCZ_ST	Q04206	RELA	Q05513	PRKCZ	S543	A538V	538	Missense	distal	-5	no	37.041	39.629	EPSD	ICGC;COSMIC	31.494	Up-regulation
AGC_PKC_PKCi_PRKCZ_ST	Q04206	RELA	Q05513	PRKCZ	S543	Q548P	548	Missense	distal	5	no	37.041	37.104	EPSD	ICGC;COSMIC	31.494	Up-regulation
AGC_PKC_PKCi_PRKCZ_ST	Q04206	RELA	Q05513	PRKCZ	S547	Q548P	548	Missense	proximal	1	no	35.118	35.507	EPSD	ICGC;COSMIC	31.494	Up-regulation
Other_PLK_PLK2_PLK3_ST	P15336	ATF2	Q9H4B4	PLK3	S127	E130K	130	Missense	distal	3	no	10.839	9.726	EPSD	ICGC;COSMIC	8.404	Down-regulation
Other_PLK_PLK2_PLK3_ST	P15336	ATF2	Q9H4B4	PLK3	T322	S321G	321	Missense	proximal	-1	no	8.380	8.958	EPSD	ICGC;COSMIC	8.404	Gain
Other_PLK_PLK2_PLK3_ST	P15336	ATF2	Q9H4B4	PLK3	T336	S340L	340	Missense	distal	4	no	8.857	9.406	EPSD	ICGC;COSMIC	8.404	Up-regulation
Other_PLK_PLK2_PLK3_ST	P15336	ATF2	Q9H4B4	PLK3	T336	Q337H	337	Missense	proximal	1	no	8.857	9.394	EPSD	ICGC;COSMIC	8.404	Up-regulation
Other_PLK_PLK2_PLK3_ST	P62258	YWHAE	Q9H4B4	PLK3	T38	R42G	42	Missense	distal	4	no	10.359	10.823	EPSD	ICGC	8.404	Up-regulation
Other_PLK_PLK2_PLK3_ST	P62258	YWHAE	Q9H4B4	PLK3	T38	L44F	44	Missense	distal	6	no	10.359	10.589	EPSD	ICGC;COSMIC	8.404	Up-regulation
Other_PLK_PLK2_PLK3_ST	P62258	YWHAE	Q9H4B4	PLK3	S46	R42G	42	Missense	distal	-4	no	11.599	11.340	EPSD	ICGC	8.404	Down-regulation
Other_PLK_PLK2_PLK3_ST	P62258	YWHAE	Q9H4B4	PLK3	S46	L44F	44	Missense	proximal	-2	no	11.599	10.059	EPSD	ICGC;COSMIC	8.404	Down-regulation
Other_PLK_PLK2_PLK3_ST	P62258	YWHAE	Q9H4B4	PLK3	T208	L206R	206	Missense	proximal	-2	no	16.671	13.307	PhosphoSitePlus	ICGC;COSMIC	8.404	Down-regulation
Other_PLK_PLK2_PLK3_ST	P62258	YWHAE	Q9H4B4	PLK3	S210	L206R	206	Missense	distal	-4	no	11.170	10.376	EPSD	ICGC;COSMIC	8.404	Down-regulation
Other_PLK_PLK2_PLK3_ST	P62258	YWHAE	Q9H4B4	PLK3	S213	L206R	206	Missense	distal	-7	no	8.508	8.443	EPSD	ICGC;COSMIC	8.404	Down-regulation
Other_PLK_PLK2_PLK3_ST	O96017	CHEK2	Q9H4B4	PLK3	S140	R145W	145	Missense	distal	5	no	10.344	10.577	EPSD	ICGC;COSMIC;CCLE	8.404	Up-regulation
Other_PLK_PLK2_PLK3_ST	O96017	CHEK2	Q9H4B4	PLK3	S140	R145Q	145	Missense	distal	5	no	10.344	10.184	EPSD	ICGC;COSMIC	8.404	Down-regulation
Other_PLK_PLK2_PLK3_ST	O96017	CHEK2	Q9H4B4	PLK3	S140	H143N	143	Missense	distal	3	no	10.344	10.096	EPSD	ICGC;COSMIC	8.404	Down-regulation
Other_PLK_PLK2_PLK3_ST	O96017	CHEK2	Q9H4B4	PLK3	S140	T138A	138	Missense	proximal	-2	no	10.344	8.214	EPSD	ICGC;COSMIC	8.404	Loss
Other_PLK_PLK2_PLK3_ST	O96017	CHEK2	Q9H4B4	PLK3	S140	H143Q	143	Missense	distal	3	no	10.344	11.164	EPSD	ICGC;COSMIC	8.404	Up-regulation
Other_PLK_PLK2_PLK3_ST	O96017	CHEK2	Q9H4B4	PLK3	S140	D134Y	134	Missense	distal	-6	no	10.344	9.515	EPSD	ICGC;COSMIC	8.404	Down-regulation
Other_PLK_PLK2_PLK3_ST	O96017	CHEK2	Q9H4B4	PLK3	S140	K135T	135	Missense	distal	-5	no	10.344	10.432	EPSD	ICGC;COSMIC	8.404	Up-regulation
Other_PLK_PLK2_PLK3_ST	O96017	CHEK2	Q9H4B4	PLK3	S164	N166S	166	Missense	proximal	2	no	11.800	11.700	EPSD	ICGC;COSMIC	8.404	Down-regulation
Other_PLK_PLK2_PLK3_ST	O96017	CHEK2	Q9H4B4	PLK3	S164	A158V	158	Missense	distal	-6	no	11.800	10.431	EPSD	ICGC;COSMIC	8.404	Down-regulation
Other_PLK_PLK2_PLK3_ST	O96017	CHEK2	Q9H4B4	PLK3	S164	T168N	168	Missense	distal	4	no	11.800	11.438	EPSD	ICGC	8.404	Down-regulation
Other_PLK_PLK2_PLK3_ST	O96017	CHEK2	Q9H4B4	PLK3	S164	H163Q	163	Missense	proximal	-1	no	11.800	11.203	EPSD	ICGC	8.404	Down-regulation
Other_PLK_PLK2_PLK3_ST	O96017	CHEK2	Q9H4B4	PLK3	S164	I157T	157	Missense	distal	-7	no	11.800	11.527	EPSD	ICGC;COSMIC	8.404	Down-regulation
Other_PLK_PLK2_PLK3_ST	O96017	CHEK2	Q9H4B4	PLK3	S164	D162N	162	Missense	proximal	-2	no	11.800	8.958	EPSD	ICGC	8.404	Down-regulation
Other_PLK_PLK2_PLK3_ST	O96017	CHEK2	Q9H4B4	PLK3	S164	E161D	161	Missense	distal	-3	no	11.800	10.384	EPSD	ICGC	8.404	Down-regulation
Other_PLK_PLK2_PLK3_ST	O96017	CHEK2	Q9H4B4	PLK3	T205	D203E	203	Missense	proximal	-2	no	7.261	10.326	EPSD	ICGC;COSMIC	8.404	Gain
Other_PLK_PLK2_PLK3_ST	O96017	CHEK2	Q9H4B4	PLK3	T225	G232R	232	Missense	distal	7	no	9.976	10.507	EPSD	ICGC;COSMIC	8.404	Up-regulation
Other_PLK_PLK2_PLK3_ST	O96017	CHEK2	Q9H4B4	PLK3	T225	G229C	229	Missense	distal	4	no	9.976	9.850	EPSD	ICGC;COSMIC	8.404	Down-regulation
Other_PLK_PLK2_PLK3_ST	O96017	CHEK2	Q9H4B4	PLK3	T225	L226F	226	Missense	proximal	1	no	9.976	10.536	EPSD	ICGC;COSMIC;CCLE	8.404	Up-regulation
Other_PLK_PLK2_PLK3_ST	O96017	CHEK2	Q9H4B4	PLK3	S357	E359K	359	Missense	proximal	2	no	9.449	7.817	EPSD	ICGC;COSMIC	8.404	Loss
Other_PLK_PLK2_PLK3_ST	O96017	CHEK2	Q9H4B4	PLK3	S357	L363F	363	Missense	distal	6	no	9.449	9.679	EPSD	ICGC;COSMIC	8.404	Up-regulation
Other_PLK_PLK2_PLK3_ST	O96017	CHEK2	Q9H4B4	PLK3	S357	L355R	355	Missense	proximal	-2	no	9.449	6.085	EPSD	ICGC	8.404	Loss
Other_PLK_PLK2_PLK3_ST	O96017	CHEK2	Q9H4B4	PLK3	S357	E351D	351	Missense	distal	-6	no	9.449	9.024	EPSD	ICGC;COSMIC	8.404	Down-regulation
Other_PLK_PLK2_PLK3_ST	O96017	CHEK2	Q9H4B4	PLK3	S357	L354V	354	Missense	distal	-3	no	9.449	8.403	EPSD	ICGC;COSMIC	8.404	Loss
Other_PLK_PLK2_PLK3_ST	O96017	CHEK2	Q9H4B4	PLK3	S372	E377K	377	Missense	distal	5	no	8.290	8.909	EPSD	ICGC;COSMIC	8.404	Gain
Other_PLK_PLK2_PLK3_ST	O96017	CHEK2	Q9H4B4	PLK3	S372	I374M	374	Missense	proximal	2	no	8.290	10.236	EPSD	ICGC	8.404	Gain
Other_PLK_PLK2_PLK3_ST	O96017	CHEK2	Q9H4B4	PLK3	S372	T378A	378	Missense	distal	6	no	8.290	8.883	EPSD	ICGC	8.404	Gain
Other_PLK_PLK2_PLK3_ST	O96017	CHEK2	Q9H4B4	PLK3	T387	L391F	391	Missense	distal	4	no	8.352	9.101	EPSD	ICGC;COSMIC	8.404	Gain
Other_PLK_PLK2_PLK3_ST	O96017	CHEK2	Q9H4B4	PLK3	S435	Q433E	433	Missense	proximal	-2	no	7.110	11.867	EPSD	ICGC;COSMIC	8.404	Gain
Other_PLK_PLK2_PLK3_ST	O96017	CHEK2	Q9H4B4	PLK3	T441	F447L	447	Missense	distal	6	no	9.441	9.212	EPSD	ICGC;COSMIC	8.404	Down-regulation
Other_PLK_PLK2_PLK3_ST	P11388	TOP2A	Q9H4B4	PLK3	S230	M228I	228	Missense	proximal	-2	no	11.179	6.249	EPSD	ICGC;COSMIC	8.404	Loss
Other_PLK_PLK2_PLK3_ST	P11388	TOP2A	Q9H4B4	PLK3	S387	Q393K	393	Missense	distal	6	no	8.839	9.226	EPSD	ICGC	8.404	Up-regulation
Other_PLK_PLK2_PLK3_ST	P11388	TOP2A	Q9H4B4	PLK3	T825	D832V	832	Missense	distal	7	no	10.489	10.190	EPSD	ICGC	8.404	Down-regulation
Other_PLK_PLK2_PLK3_ST	P11388	TOP2A	Q9H4B4	PLK3	T825	H824Y	824	Missense	proximal	-1	no	10.489	9.783	EPSD	ICGC	8.404	Down-regulation
Other_PLK_PLK2_PLK3_ST	P11388	TOP2A	Q9H4B4	PLK3	T825	T825M	825	Missense	central	0	yes	10.489	0.000	EPSD	ICGC;COSMIC	8.404	Loss
Other_PLK_PLK2_PLK3_ST	P11388	TOP2A	Q9H4B4	PLK3	T898	N894D	894	Missense	distal	-4	no	8.855	11.088	EPSD	ICGC;COSMIC	8.404	Up-regulation
Other_PLK_PLK2_PLK3_ST	P11388	TOP2A	Q9H4B4	PLK3	T950	M943T	943	Missense	distal	-7	no	9.241	9.337	EPSD	ICGC	8.404	Up-regulation
Other_PLK_PLK2_PLK3_ST	P11388	TOP2A	Q9H4B4	PLK3	S1106	E1104K	1104	Missense	proximal	-2	no	9.872	4.976	EPSD	ICGC	8.404	Loss
Other_PLK_PLK2_PLK3_ST	P11388	TOP2A	Q9H4B4	PLK3	S1106	E1109K	1109	Missense	distal	3	no	9.872	8.759	EPSD	ICGC;COSMIC	8.404	Down-regulation
Other_PLK_PLK2_PLK3_ST	P11388	TOP2A	Q9H4B4	PLK3	S1115	G1122E	1122	Missense	distal	7	no	10.674	11.809	EPSD	ICGC;COSMIC	8.404	Up-regulation
Other_PLK_PLK2_PLK3_ST	P11388	TOP2A	Q9H4B4	PLK3	S1115	E1109K	1109	Missense	distal	-6	no	10.674	8.268	EPSD	ICGC;COSMIC	8.404	Loss
Other_PLK_PLK2_PLK3_ST	P11388	TOP2A	Q9H4B4	PLK3	T1119	P1123Q	1123	Missense	distal	4	no	11.164	10.135	EPSD	ICGC	8.404	Down-regulation
Other_PLK_PLK2_PLK3_ST	P11388	TOP2A	Q9H4B4	PLK3	T1119	G1122E	1122	Missense	distal	3	no	11.164	12.797	EPSD	ICGC;COSMIC	8.404	Up-regulation
Other_PLK_PLK2_PLK3_ST	P11388	TOP2A	Q9H4B4	PLK3	S1121	P1123Q	1123	Missense	proximal	2	no	11.717	12.006	EPSD	ICGC	8.404	Up-regulation
Other_PLK_PLK2_PLK3_ST	P11388	TOP2A	Q9H4B4	PLK3	S1121	G1122E	1122	Missense	proximal	1	no	11.717	10.588	EPSD	ICGC;COSMIC	8.404	Down-regulation
Other_PLK_PLK2_PLK3_ST	P11388	TOP2A	Q9H4B4	PLK3	T1124	G1122E	1122	Missense	proximal	-2	no	7.704	12.843	EPSD	ICGC;COSMIC	8.404	Gain
Other_PLK_PLK2_PLK3_ST	P11388	TOP2A	Q9H4B4	PLK3	S1162	L1166F	1166	Missense	distal	4	no	7.919	8.668	EPSD	ICGC;COSMIC	8.404	Gain
Other_PLK_PLK2_PLK3_ST	P11388	TOP2A	Q9H4B4	PLK3	T1272	T1274A	1274	Missense	proximal	2	no	10.675	9.523	EPSD	ICGC;COSMIC	8.404	Down-regulation
Other_PLK_PLK2_PLK3_ST	P11388	TOP2A	Q9H4B4	PLK3	T1272	K1267R	1267	Missense	distal	-5	no	10.675	10.476	EPSD	ICGC;COSMIC	8.404	Down-regulation
Other_PLK_PLK2_PLK3_ST	P11388	TOP2A	Q9H4B4	PLK3	S1302	S1302I	1302	Missense	central	0	yes	10.669	0.000	EPSD	ICGC	8.404	Loss
Other_PLK_PLK2_PLK3_ST	P11388	TOP2A	Q9H4B4	PLK3	T1327	T1322P	1322	Missense	distal	-5	no	8.466	9.262	EPSD	ICGC	8.404	Up-regulation
Other_PLK_PLK2_PLK3_ST	P11388	TOP2A	Q9H4B4	PLK3	T1343	P1350T	1350	Missense	distal	7	no	22.301	21.611	PhosphoSitePlus	ICGC;COSMIC	8.404	Down-regulation
Other_PLK_PLK2_PLK3_ST	P11388	TOP2A	Q9H4B4	PLK3	S1377	V1376M	1376	Missense	proximal	-1	no	10.867	11.153	EPSD	ICGC;COSMIC	8.404	Up-regulation
Other_PLK_PLK2_PLK3_ST	P11388	TOP2A	Q9H4B4	PLK3	S1393	P1395T	1395	Missense	proximal	2	no	9.666	11.345	EPSD	ICGC;COSMIC	8.404	Up-regulation
Other_PLK_PLK2_PLK3_ST	P11388	TOP2A	Q9H4B4	PLK3	S1393	P1394T	1394	Missense	proximal	1	no	9.666	8.344	EPSD	ICGC;COSMIC	8.404	Loss
Other_PLK_PLK2_PLK3_ST	P11388	TOP2A	Q9H4B4	PLK3	T1403	E1404K	1404	Missense	proximal	1	no	7.375	8.460	EPSD	ICGC;COSMIC	8.404	Gain
Other_PLK_PLK2_PLK3_ST	P11388	TOP2A	Q9H4B4	PLK3	T1470	R1464C	1464	Missense	distal	-6	no	10.946	12.103	EPSD	ICGC;COSMIC	8.404	Up-regulation
Other_PLK_PLK2_PLK3_ST	P11388	TOP2A	Q9H4B4	PLK3	T1470	S1469P	1469	Missense	proximal	-1	no	10.946	11.173	EPSD	ICGC	8.404	Up-regulation
Other_PLK_PLK2_PLK3_ST	P11388	TOP2A	Q9H4B4	PLK3	T1470	R1466T	1466	Missense	distal	-4	no	10.946	10.582	EPSD	ICGC;COSMIC	8.404	Down-regulation
Other_PLK_PLK2_PLK3_ST	P11388	TOP2A	Q9H4B4	PLK3	T1470	D1473Y	1473	Missense	distal	3	no	10.946	10.901	EPSD	ICGC;COSMIC	8.404	Down-regulation
Other_PLK_PLK2_PLK3_ST	P60484	PTEN	Q9H4B4	PLK3	S294	E291Q	291	Missense	distal	-3	no	11.776	8.772	EPSD	ICGC;COSMIC	8.404	Down-regulation
Other_PLK_PLK2_PLK3_ST	P60484	PTEN	Q9H4B4	PLK3	T350	L345P	345	Missense	distal	-5	no	8.035	9.082	EPSD	ICGC;COSMIC	8.404	Gain
Other_PLK_PLK2_PLK3_ST	P60484	PTEN	Q9H4B4	PLK3	S355	S360R	360	Missense	distal	5	no	11.481	11.381	EPSD	ICGC	8.404	Down-regulation
Other_PLK_PLK2_PLK3_ST	P60484	PTEN	Q9H4B4	PLK3	S355	P354L	354	Missense	proximal	-1	no	11.481	11.406	EPSD	ICGC;COSMIC	8.404	Down-regulation
Other_PLK_PLK2_PLK3_ST	P60484	PTEN	Q9H4B4	PLK3	S361	S360R	360	Missense	proximal	-1	no	8.850	8.664	EPSD	ICGC	8.404	Down-regulation
Other_PLK_PLK2_PLK3_ST	P60484	PTEN	Q9H4B4	PLK3	S361	P354L	354	Missense	distal	-7	no	8.850	8.229	EPSD	ICGC;COSMIC	8.404	Loss
Other_PLK_PLK2_PLK3_ST	P60484	PTEN	Q9H4B4	PLK3	S362	S360R	360	Missense	proximal	-2	no	10.455	8.170	EPSD	ICGC	8.404	Loss
Other_PLK_PLK2_PLK3_ST	P60484	PTEN	Q9H4B4	PLK3	T366	S360R	360	Missense	distal	-6	no	17.213	15.123	PhosphoSitePlus;EPSD	ICGC	8.404	Down-regulation
Other_PLK_PLK2_PLK3_ST	P08238	HSP90AB1	Q9H4B4	PLK3	S45	D52Y	52	Missense	distal	7	no	9.492	10.464	EPSD	ICGC	8.404	Up-regulation
Other_PLK_PLK2_PLK3_ST	P08238	HSP90AB1	Q9H4B4	PLK3	S45	A47T	47	Missense	proximal	2	no	9.492	10.644	EPSD	ICGC	8.404	Up-regulation
Other_PLK_PLK2_PLK3_ST	P08238	HSP90AB1	Q9H4B4	PLK3	S58	D52Y	52	Missense	distal	-6	no	11.600	10.772	EPSD	ICGC	8.404	Down-regulation
Other_PLK_PLK2_PLK3_ST	P08238	HSP90AB1	Q9H4B4	PLK3	S58	R55L	55	Missense	distal	-3	no	11.600	13.450	EPSD	ICGC	8.404	Up-regulation
Other_PLK_PLK2_PLK3_ST	P08238	HSP90AB1	Q9H4B4	PLK3	S164	R168C	168	Missense	distal	4	no	8.346	8.684	EPSD	ICGC;COSMIC	8.404	Gain
Other_PLK_PLK2_PLK3_ST	P08238	HSP90AB1	Q9H4B4	PLK3	T297	P293A	293	Missense	distal	-4	no	11.067	10.768	EPSD	ICGC;COSMIC	8.404	Down-regulation
Other_PLK_PLK2_PLK3_ST	P08238	HSP90AB1	Q9H4B4	PLK3	S434	K428T	428	Missense	distal	-6	no	12.129	13.579	EPSD	ICGC	8.404	Up-regulation
Other_PLK_PLK2_PLK3_ST	P08238	HSP90AB1	Q9H4B4	PLK3	T467	Q461H	461	Missense	distal	-6	no	8.268	9.264	EPSD	ICGC	8.404	Gain
Other_PLK_PLK2_PLK3_ST	P08238	HSP90AB1	Q9H4B4	PLK3	T467	M466I	466	Missense	proximal	-1	no	8.268	9.342	EPSD	ICGC;COSMIC	8.404	Gain
Other_PLK_PLK2_PLK3_ST	P08238	HSP90AB1	Q9H4B4	PLK3	S468	R475C	475	Missense	distal	7	no	11.153	10.482	EPSD	ICGC;COSMIC	8.404	Down-regulation
Other_PLK_PLK2_PLK3_ST	P08238	HSP90AB1	Q9H4B4	PLK3	S468	R475H	475	Missense	distal	7	no	11.153	10.880	EPSD	ICGC;COSMIC	8.404	Down-regulation
Other_PLK_PLK2_PLK3_ST	P08238	HSP90AB1	Q9H4B4	PLK3	S468	Q461H	461	Missense	distal	-7	no	11.153	11.112	EPSD	ICGC	8.404	Down-regulation
Other_PLK_PLK2_PLK3_ST	P08238	HSP90AB1	Q9H4B4	PLK3	S468	M466I	466	Missense	proximal	-2	no	11.153	6.223	EPSD	ICGC;COSMIC	8.404	Loss
Other_PLK_PLK2_PLK3_ST	P08238	HSP90AB1	Q9H4B4	PLK3	S474	R475C	475	Missense	proximal	1	no	11.232	11.621	EPSD	ICGC;COSMIC	8.404	Up-regulation
Other_PLK_PLK2_PLK3_ST	P08238	HSP90AB1	Q9H4B4	PLK3	S474	R475H	475	Missense	proximal	1	no	11.232	11.870	EPSD	ICGC;COSMIC	8.404	Up-regulation
Other_PLK_PLK2_PLK3_ST	P08238	HSP90AB1	Q9H4B4	PLK3	S482	R475C	475	Missense	distal	-7	no	9.552	9.505	EPSD	ICGC;COSMIC	8.404	Down-regulation
Other_PLK_PLK2_PLK3_ST	P08238	HSP90AB1	Q9H4B4	PLK3	S482	R475H	475	Missense	distal	-7	no	9.552	9.664	EPSD	ICGC;COSMIC	8.404	Up-regulation
Other_PLK_PLK2_PLK3_ST	P08238	HSP90AB1	Q9H4B4	PLK3	S482	I486V	486	Missense	distal	4	no	9.552	8.687	EPSD	ICGC;COSMIC	8.404	Down-regulation
Other_PLK_PLK2_PLK3_ST	P08238	HSP90AB1	Q9H4B4	PLK3	S482	G488V	488	Missense	distal	6	no	9.552	8.951	EPSD	ICGC;COSMIC	8.404	Down-regulation
Other_PLK_PLK2_PLK3_ST	P08238	HSP90AB1	Q9H4B4	PLK3	S556	E549K	549	Missense	distal	-7	no	8.238	8.692	EPSD	ICGC;COSMIC	8.404	Gain
Other_PLK_PLK2_PLK3_ST	P08238	HSP90AB1	Q9H4B4	PLK3	T579	L584R	584	Missense	distal	5	no	10.122	10.228	EPSD	ICGC	8.404	Up-regulation
Other_PLK_PLK2_PLK3_ST	P08238	HSP90AB1	Q9H4B4	PLK3	S718	L711V	711	Missense	distal	-7	no	9.874	9.781	PhosphoSitePlus	ICGC;COSMIC	8.404	Down-regulation
Other_PLK_PLK2_PLK3_ST	P08238	HSP90AB1	Q9H4B4	PLK3	S718	R719H	719	Missense	proximal	1	no	9.874	10.512	PhosphoSitePlus	ICGC;COSMIC	8.404	Up-regulation
Other_PLK_PLK2_PLK3_ST	P08238	HSP90AB1	Q9H4B4	PLK3	S718	E712K	712	Missense	distal	-6	no	9.874	7.468	PhosphoSitePlus	ICGC;COSMIC	8.404	Loss
Other_PLK_PLK2_PLK3_ST	P06748	NPM1	Q9H4B4	PLK3	S4	M9I	9	Missense	distal	5	no	15.746	15.707	PhosphoSitePlus	ICGC	8.404	Down-regulation
Other_PLK_PLK2_PLK3_ST	P06748	NPM1	Q9H4B4	PLK3	S4	D3H	3	Missense	proximal	-1	no	15.746	16.036	PhosphoSitePlus	ICGC;COSMIC	8.404	Up-regulation
Other_PLK_PLK2_PLK3_ST	P06748	NPM1	Q9H4B4	PLK3	S10	M9I	9	Missense	proximal	-1	no	8.628	9.702	EPSD	ICGC	8.404	Up-regulation
Other_PLK_PLK2_PLK3_ST	P06748	NPM1	Q9H4B4	PLK3	S10	D3H	3	Missense	distal	-7	no	8.628	8.883	EPSD	ICGC;COSMIC	8.404	Up-regulation
Other_PLK_PLK2_PLK3_ST	P06748	NPM1	Q9H4B4	PLK3	S139	R142W	142	Missense	distal	3	no	10.224	11.948	EPSD	ICGC	8.404	Up-regulation
Other_PLK_PLK2_PLK3_ST	P06748	NPM1	Q9H4B4	PLK3	S143	R142W	142	Missense	proximal	-1	no	9.238	9.753	EPSD	ICGC	8.404	Up-regulation
Other_PLK_PLK2_PLK3_ST	P06748	NPM1	Q9H4B4	PLK3	S243	D246Y	246	Missense	distal	3	no	10.094	10.049	EPSD	ICGC	8.404	Down-regulation
Other_PLK_PLK2_PLK3_ST	P06748	NPM1	Q9H4B4	PLK3	S254	S254I	254	Missense	central	0	yes	11.211	0.000	EPSD	ICGC	8.404	Loss
Other_PLK_PLK2_PLK3_ST	P30307	CDC25C	Q9H4B4	PLK3	T40	L33P	33	Missense	distal	-7	no	9.545	10.165	EPSD	ICGC;COSMIC	8.404	Up-regulation
Other_PLK_PLK2_PLK3_ST	P30307	CDC25C	Q9H4B4	PLK3	S57	G55S	55	Missense	proximal	-2	no	10.785	11.195	EPSD	ICGC;COSMIC	8.404	Up-regulation
Other_PLK_PLK2_PLK3_ST	P30307	CDC25C	Q9H4B4	PLK3	S57	A58E	58	Missense	proximal	1	no	10.785	9.371	EPSD	ICGC	8.404	Down-regulation
Other_PLK_PLK2_PLK3_ST	P30307	CDC25C	Q9H4B4	PLK3	S168	T172A	172	Missense	distal	4	no	10.346	11.160	EPSD	ICGC;COSMIC	8.404	Up-regulation
Other_PLK_PLK2_PLK3_ST	P30307	CDC25C	Q9H4B4	PLK3	T171	T172A	172	Missense	proximal	1	no	8.079	9.277	EPSD	ICGC;COSMIC	8.404	Gain
Other_PLK_PLK2_PLK3_ST	P30307	CDC25C	Q9H4B4	PLK3	S198	Q202K	202	Missense	distal	4	no	14.670	15.137	PhosphoSitePlus;EPSD	ICGC	8.404	Up-regulation
Other_PLK_PLK2_PLK3_ST	P30307	CDC25C	Q9H4B4	PLK3	S277	G280W	280	Missense	distal	3	no	9.436	10.277	EPSD	ICGC;COSMIC	8.404	Up-regulation
Other_PLK_PLK2_PLK3_ST	P05412	JUN	Q9H4B4	PLK3	T8	L14F	14	Missense	distal	6	no	9.222	9.452	EPSD	ICGC;COSMIC	8.404	Up-regulation
Other_PLK_PLK2_PLK3_ST	P05412	JUN	Q9H4B4	PLK3	T8	D11N	11	Missense	distal	3	no	9.222	7.883	EPSD	ICGC	8.404	Loss
Other_PLK_PLK2_PLK3_ST	P05412	JUN	Q9H4B4	PLK3	T8	A3T	3	Missense	distal	-5	no	9.222	10.111	EPSD	ICGC;COSMIC	8.404	Up-regulation
Other_PLK_PLK2_PLK3_ST	P05412	JUN	Q9H4B4	PLK3	T8	N15K	15	Missense	distal	7	no	9.222	9.432	EPSD	ICGC;COSMIC	8.404	Up-regulation
Other_PLK_PLK2_PLK3_ST	P05412	JUN	Q9H4B4	PLK3	S63	K70T	70	Missense	distal	7	no	17.555	17.156	EPSD;PhosphoSitePlus	ICGC;COSMIC	8.404	Down-regulation
Other_PLK_PLK2_PLK3_ST	P05412	JUN	Q9H4B4	PLK3	S73	A72E	72	Missense	proximal	-1	no	16.576	15.861	PhosphoSitePlus;EPSD	ICGC;COSMIC	8.404	Down-regulation
Other_PLK_PLK2_PLK3_ST	P05412	JUN	Q9H4B4	PLK3	S73	K70T	70	Missense	distal	-3	no	16.576	17.171	PhosphoSitePlus;EPSD	ICGC;COSMIC	8.404	Up-regulation
Other_PLK_PLK2_PLK3_ST	P04637	TP53	Q9H4B4	PLK3	S9	E11K	11	Missense	proximal	2	no	9.149	7.516	EPSD	ICGC;COSMIC	8.404	Loss
Other_PLK_PLK2_PLK3_ST	P04637	TP53	Q9H4B4	PLK3	S20	W23C	23	Missense	distal	3	no	14.863	13.049	PhosphoSitePlus	ICGC;COSMIC	8.404	Down-regulation
Other_PLK_PLK2_PLK3_ST	P04637	TP53	Q9H4B4	PLK3	S46	D48G	48	Missense	proximal	2	no	10.086	8.509	EPSD	ICGC;COSMIC	8.404	Down-regulation
Other_PLK_PLK2_PLK3_ST	P04637	TP53	Q9H4B4	PLK3	S46	Q52K	52	Missense	distal	6	no	10.086	10.472	EPSD	ICGC	8.404	Up-regulation
Other_PLK_PLK2_PLK3_ST	P04637	TP53	Q9H4B4	PLK3	T150	R156L	156	Missense	distal	6	no	9.520	10.019	EPSD	ICGC;COSMIC	8.404	Up-regulation
Other_PLK_PLK2_PLK3_ST	P04637	TP53	Q9H4B4	PLK3	T150	L145Q	145	Missense	distal	-5	no	9.520	9.383	EPSD	ICGC;COSMIC	8.404	Down-regulation
Other_PLK_PLK2_PLK3_ST	P04637	TP53	Q9H4B4	PLK3	T150	P152R	152	Missense	proximal	2	no	9.520	9.202	EPSD	ICGC;COSMIC	8.404	Down-regulation
Other_PLK_PLK2_PLK3_ST	P04637	TP53	Q9H4B4	PLK3	T150	G154S	154	Missense	distal	4	no	9.520	9.339	EPSD	ICGC;COSMIC	8.404	Down-regulation
Other_PLK_PLK2_PLK3_ST	P04637	TP53	Q9H4B4	PLK3	T150	V157A	157	Missense	distal	7	no	9.520	9.820	EPSD	ICGC;COSMIC	8.404	Up-regulation
Other_PLK_PLK2_PLK3_ST	P04637	TP53	Q9H4B4	PLK3	T150	P151F	151	Missense	proximal	1	no	9.520	10.169	EPSD	ICGC;COSMIC	8.404	Up-regulation
Other_PLK_PLK2_PLK3_ST	P04637	TP53	Q9H4B4	PLK3	T150	V147G	147	Missense	distal	-3	no	9.520	8.948	EPSD	ICGC;COSMIC;GDSC;CCLE	8.404	Down-regulation
Other_PLK_PLK2_PLK3_ST	P04637	TP53	Q9H4B4	PLK3	S183	C182W	182	Missense	proximal	-1	no	12.054	12.082	EPSD	ICGC;COSMIC	8.404	Up-regulation
Other_PLK_PLK2_PLK3_ST	P04637	TP53	Q9H4B4	PLK3	S183	H178D	178	Missense	distal	-5	no	12.054	10.254	EPSD	ICGC;COSMIC;CCLE	8.404	Down-regulation
Other_PLK_PLK2_PLK3_ST	P04637	TP53	Q9H4B4	PLK3	S183	D184H	184	Missense	proximal	1	no	12.054	12.150	EPSD	ICGC;COSMIC	8.404	Up-regulation
Other_PLK_PLK2_PLK3_ST	P04637	TP53	Q9H4B4	PLK3	S183	A189T	189	Missense	distal	6	no	12.054	11.461	EPSD	ICGC;COSMIC	8.404	Down-regulation
Other_PLK_PLK2_PLK3_ST	P04637	TP53	Q9H4B4	PLK3	S183	P190T	190	Missense	distal	7	no	12.054	11.364	EPSD	ICGC;COSMIC	8.404	Down-regulation
Other_PLK_PLK2_PLK3_ST	P04637	TP53	Q9H4B4	PLK3	S183	P190S	190	Missense	distal	7	no	12.054	12.149	EPSD	ICGC;COSMIC	8.404	Up-regulation
Other_PLK_PLK2_PLK3_ST	P04637	TP53	Q9H4B4	PLK3	S183	A189D	189	Missense	distal	6	no	12.054	12.199	EPSD	ICGC;COSMIC	8.404	Up-regulation
Other_PLK_PLK2_PLK3_ST	P04637	TP53	Q9H4B4	PLK3	S183	E180D	180	Missense	distal	-3	no	12.054	10.638	EPSD	ICGC;COSMIC	8.404	Down-regulation
Other_PLK_PLK2_PLK3_ST	P04637	TP53	Q9H4B4	PLK3	S183	C176G	176	Missense	distal	-7	no	12.054	12.497	EPSD	ICGC;COSMIC	8.404	Up-regulation
Other_PLK_PLK2_PLK3_ST	P04637	TP53	Q9H4B4	PLK3	T304	P301T	301	Missense	distal	-3	no	7.878	9.186	EPSD	ICGC;COSMIC	8.404	Gain
Other_PLK_PLK2_PLK3_ST	P04637	TP53	Q9H4B4	PLK3	S315	T312I	312	Missense	distal	-3	no	11.511	6.689	EPSD	ICGC;COSMIC	8.404	Loss
Other_PLK_PLK2_PLK3_ST	P04637	TP53	Q9H4B4	PLK3	S315	P322T	322	Missense	distal	7	no	11.511	10.821	EPSD	ICGC	8.404	Down-regulation
Other_PLK_PLK2_PLK3_ST	P14635	CCNB1	Q9H4B4	PLK3	S116	P109L	109	Missense	distal	-7	no	8.529	7.908	EPSD	ICGC;COSMIC	8.404	Loss
Other_PLK_PLK2_PLK3_ST	P14635	CCNB1	Q9H4B4	PLK3	S116	E118D	118	Missense	proximal	2	no	8.529	8.374	EPSD	ICGC;COSMIC	8.404	Loss
Other_PLK_PLK2_PLK3_ST	P14635	CCNB1	Q9H4B4	PLK3	S116	L121F	121	Missense	distal	5	no	8.529	8.954	EPSD	ICGC;COSMIC	8.404	Up-regulation
Other_PLK_PLK2_PLK3_ST	P14635	CCNB1	Q9H4B4	PLK3	S133	S128I	128	Missense	distal	-5	no	15.446	16.613	PhosphoSitePlus	ICGC	8.404	Up-regulation
Other_PLK_PLK2_PLK3_ST	Q14790	CASP8	Q9H4B4	PLK3	S26	F24I	24	Missense	proximal	-2	no	8.632	5.145	EPSD	ICGC	8.404	Loss
Other_PLK_PLK2_PLK3_ST	Q14790	CASP8	Q9H4B4	PLK3	S26	F24L	24	Missense	proximal	-2	no	8.632	10.171	EPSD	ICGC;COSMIC	8.404	Up-regulation
Other_PLK_PLK2_PLK3_ST	Q14790	CASP8	Q9H4B4	PLK3	S26	L22I	22	Missense	distal	-4	no	8.632	8.130	EPSD	ICGC;COSMIC	8.404	Loss
Other_PLK_PLK2_PLK3_ST	Q14790	CASP8	Q9H4B4	PLK3	S26	L22F	22	Missense	distal	-4	no	8.632	9.483	EPSD	ICGC;COSMIC	8.404	Up-regulation
Other_PLK_PLK2_PLK3_ST	Q14790	CASP8	Q9H4B4	PLK3	S26	Y29D	29	Missense	distal	3	no	8.632	8.677	EPSD	ICGC;COSMIC	8.404	Up-regulation
Other_PLK_PLK2_PLK3_ST	Q14790	CASP8	Q9H4B4	PLK3	S26	D28G	28	Missense	proximal	2	no	8.632	7.055	EPSD	ICGC;COSMIC	8.404	Loss
Other_PLK_PLK2_PLK3_ST	Q14790	CASP8	Q9H4B4	PLK3	S26	L25P	25	Missense	proximal	-1	no	8.632	8.707	EPSD	ICGC;COSMIC	8.404	Up-regulation
Other_PLK_PLK2_PLK3_ST	Q14790	CASP8	Q9H4B4	PLK3	S26	P31L	31	Missense	distal	5	no	8.632	8.465	EPSD	ICGC;COSMIC	8.404	Down-regulation
Other_PLK_PLK2_PLK3_ST	Q14790	CASP8	Q9H4B4	PLK3	S26	L27M	27	Missense	proximal	1	no	8.632	8.142	EPSD	ICGC;COSMIC	8.404	Loss
Other_PLK_PLK2_PLK3_ST	Q14790	CASP8	Q9H4B4	PLK3	S113	S115L	115	Missense	proximal	2	no	8.576	7.713	EPSD	ICGC;COSMIC	8.404	Loss
Other_PLK_PLK2_PLK3_ST	Q14790	CASP8	Q9H4B4	PLK3	S113	S109L	109	Missense	distal	-4	no	8.576	9.988	EPSD	ICGC;COSMIC;CCLE	8.404	Up-regulation
Other_PLK_PLK2_PLK3_ST	Q14790	CASP8	Q9H4B4	PLK3	S113	R118G	118	Missense	distal	5	no	8.576	8.564	EPSD	ICGC;COSMIC	8.404	Down-regulation
Other_PLK_PLK2_PLK3_ST	Q14790	CASP8	Q9H4B4	PLK3	S113	Y106D	106	Missense	distal	-7	no	8.576	8.890	EPSD	ICGC;COSMIC	8.404	Up-regulation
Other_PLK_PLK2_PLK3_ST	Q14790	CASP8	Q9H4B4	PLK3	S113	I108N	108	Missense	distal	-5	no	8.576	7.237	EPSD	ICGC;COSMIC	8.404	Loss
Other_PLK_PLK2_PLK3_ST	Q14790	CASP8	Q9H4B4	PLK3	S113	V112A	112	Missense	proximal	-1	no	8.576	9.006	EPSD	ICGC;CCLE	8.404	Up-regulation
Other_PLK_PLK2_PLK3_ST	Q14790	CASP8	Q9H4B4	PLK3	S113	S113R	113	Missense	central	0	yes	8.576	0.000	EPSD	ICGC;COSMIC	8.404	Loss
Other_PLK_PLK2_PLK3_ST	Q14790	CASP8	Q9H4B4	PLK3	S113	R118K	118	Missense	distal	5	no	8.576	8.255	EPSD	ICGC;COSMIC	8.404	Loss
Other_PLK_PLK2_PLK3_ST	P30304	CDC25A	Q9H4B4	PLK3	S239	S235L	235	Missense	distal	-4	no	10.258	11.669	EPSD	ICGC;COSMIC	8.404	Up-regulation
Other_PLK_PLK2_PLK3_ST	P30304	CDC25A	Q9H4B4	PLK3	S266	S263F	263	Missense	distal	-3	no	8.413	8.706	EPSD	ICGC	8.404	Up-regulation
Other_PLK_PLK2_PLK3_ST	P30304	CDC25A	Q9H4B4	PLK3	S279	P285H	285	Missense	distal	6	no	11.102	11.131	EPSD	ICGC;COSMIC	8.404	Up-regulation
Other_PLK_PLK2_PLK3_ST	P30304	CDC25A	Q9H4B4	PLK3	S283	P285H	285	Missense	proximal	2	no	8.152	9.385	EPSD	ICGC;COSMIC	8.404	Gain
Other_PLK_PLK2_PLK3_ST	P30304	CDC25A	Q9H4B4	PLK3	S317	A319E	319	Missense	proximal	2	no	7.385	9.425	EPSD	ICGC;COSMIC	8.404	Gain
Other_PLK_PLK2_PLK3_ST	P30304	CDC25A	Q9H4B4	PLK3	S321	A319E	319	Missense	proximal	-2	no	6.160	11.350	EPSD	ICGC;COSMIC	8.404	Gain
Other_PLK_PLK2_PLK3_ST	P30304	CDC25A	Q9H4B4	PLK3	S513	R506Q	506	Missense	distal	-7	no	10.260	10.412	EPSD	ICGC;COSMIC	8.404	Up-regulation
Other_PLK_PLK2_PLK3_ST	Q16143	SNCB	Q9H4B4	PLK3	S118	P123H	123	Missense	distal	5	no	12.203	12.623	PhosphoSitePlus	ICGC;COSMIC	8.404	Up-regulation
Other_PLK_PLK2_PLK3_ST	Q16665	HIF1A	Q9H4B4	PLK3	S58	D55H	55	Missense	distal	-3	no	11.014	9.024	EPSD	ICGC;COSMIC	8.404	Down-regulation
Other_PLK_PLK2_PLK3_ST	Q07817	BCL2L1	Q9H4B4	PLK3	S49	E44D	44	Missense	distal	-5	no	16.063	15.801	PhosphoSitePlus	ICGC;COSMIC	8.404	Down-regulation
Other_PLK_PLK2_PLK3_ST	Q07817	BCL2L1	Q9H4B4	PLK3	S49	T47I	47	Missense	proximal	-2	no	16.063	10.448	PhosphoSitePlus	ICGC;COSMIC	8.404	Down-regulation
Other_PLK_PLK2_PLK3_ST	P37840	SNCA	Q9H4B4	PLK3	S129	Q134K	134	Missense	distal	5	no	13.118	12.957	PhosphoSitePlus	ICGC;COSMIC	8.404	Down-regulation
CMGC_MAPK_JNK_MAPK10_ST	P01106	MYC	P53779	MAPK10	S71	P72S	72	Missense	proximal	1	no	0.024	-0.003	PhosphoSitePlus;EPSD	ICGC;COSMIC;GDSC	0.000	Loss
CMGC_MAPK_JNK_MAPK10_ST	P01106	MYC	P53779	MAPK10	S71	P72A	72	Missense	proximal	1	no	0.024	-0.001	PhosphoSitePlus;EPSD	ICGC;COSMIC	0.000	Loss
CMGC_MAPK_JNK_MAPK10_ST	P01106	MYC	P53779	MAPK10	S71	P72L	72	Missense	proximal	1	no	0.024	-0.002	PhosphoSitePlus;EPSD	ICGC;COSMIC	0.000	Loss
CMGC_MAPK_JNK_MAPK10_ST	P01106	MYC	P53779	MAPK10	S71	P72T	72	Missense	proximal	1	no	0.024	-0.001	PhosphoSitePlus;EPSD	ICGC;COSMIC;GDSC	0.000	Loss
CMGC_MAPK_JNK_MAPK10_ST	P38936	CDKN1A	P53779	MAPK10	S130	P131T	131	Missense	proximal	1	no	0.023	-0.002	PhosphoSitePlus;EPSD	ICGC;COSMIC	0.000	Loss
CMGC_MAPK_JNK_MAPK10_ST	P38936	CDKN1A	P53779	MAPK10	S130	P131Q	131	Missense	proximal	1	no	0.023	-0.001	PhosphoSitePlus;EPSD	ICGC;COSMIC	0.000	Loss
CMGC_MAPK_JNK_MAPK10_ST	P54259	ATN1	P53779	MAPK10	S34	P35T	35	Missense	proximal	1	no	0.023	-0.002	EPSD	ICGC;COSMIC	0.000	Loss
CMGC_MAPK_JNK_MAPK10_ST	P54259	ATN1	P53779	MAPK10	S103	D104Y	104	Missense	proximal	1	no	0.000	0.001	EPSD	ICGC	0.000	Up-regulation
CMGC_MAPK_JNK_MAPK10_ST	P54259	ATN1	P53779	MAPK10	T131	S132P	132	Missense	proximal	1	no	-0.003	0.023	EPSD	ICGC	0.000	Gain
CMGC_MAPK_JNK_MAPK10_ST	P54259	ATN1	P53779	MAPK10	S132	S132P	132	Missense	central	0	yes	0.023	0.000	EPSD	ICGC	0.000	Loss
CMGC_MAPK_JNK_MAPK10_ST	P54259	ATN1	P53779	MAPK10	S168	P169T	169	Missense	proximal	1	no	0.023	-0.002	EPSD	ICGC	0.000	Loss
CMGC_MAPK_JNK_MAPK10_ST	P54259	ATN1	P53779	MAPK10	S263	S264N	264	Missense	proximal	1	no	-0.002	0.000	EPSD	ICGC	0.000	Gain
CMGC_MAPK_JNK_MAPK10_ST	P54259	ATN1	P53779	MAPK10	S677	S677L	677	Missense	central	0	yes	0.022	0.000	EPSD	ICGC;COSMIC	0.000	Loss
CMGC_MAPK_JNK_MAPK10_ST	P54259	ATN1	P53779	MAPK10	S707	L708P	708	Missense	proximal	1	no	-0.002	0.023	EPSD	ICGC;COSMIC	0.000	Gain
CMGC_MAPK_JNK_MAPK10_ST	P54259	ATN1	P53779	MAPK10	S739	P740T	740	Missense	proximal	1	no	0.023	-0.002	PhosphoSitePlus	ICGC;COSMIC	0.000	Loss
CMGC_MAPK_JNK_MAPK10_ST	P54259	ATN1	P53779	MAPK10	S780	S780R	780	Missense	central	0	yes	0.000	0.000	EPSD	ICGC;CCLE	0.000	Loss
CMGC_MAPK_JNK_MAPK10_ST	P55957	BID	P53779	MAPK10	T147	T147I	147	Missense	central	0	yes	0.000	0.000	EPSD	ICGC	0.000	Loss
CMGC_MAPK_JNK_MAPK10_ST	O95644	NFATC1	P53779	MAPK10	S117	S124L	124	Missense	distal	7	no	0.024	0.023	EPSD	ICGC;COSMIC	0.000	Down-regulation
CMGC_MAPK_JNK_MAPK10_ST	O95644	NFATC1	P53779	MAPK10	S117	R119H	119	Missense	proximal	2	no	0.024	0.023	EPSD	ICGC;COSMIC	0.000	Down-regulation
CMGC_MAPK_JNK_MAPK10_ST	O95644	NFATC1	P53779	MAPK10	S117	E121K	121	Missense	distal	4	no	0.024	0.023	EPSD	ICGC;COSMIC	0.000	Down-regulation
CMGC_MAPK_JNK_MAPK10_ST	O95644	NFATC1	P53779	MAPK10	S151	S151P	151	Missense	central	0	yes	0.023	0.000	EPSD	ICGC;COSMIC	0.000	Loss
CMGC_MAPK_JNK_MAPK10_ST	O95644	NFATC1	P53779	MAPK10	S151	S151C	151	Missense	central	0	yes	0.023	0.000	EPSD	ICGC;COSMIC	0.000	Loss
CMGC_MAPK_JNK_MAPK10_ST	O95644	NFATC1	P53779	MAPK10	S151	P152L	152	Missense	proximal	1	no	0.023	-0.003	EPSD	ICGC;COSMIC	0.000	Loss
CMGC_MAPK_JNK_MAPK10_ST	O95644	NFATC1	P53779	MAPK10	S176	L177M	177	Missense	proximal	1	no	-0.002	0.000	EPSD	ICGC;COSMIC	0.000	Gain
CMGC_MAPK_JNK_MAPK10_ST	O95644	NFATC1	P53779	MAPK10	S184	E185D	185	Missense	proximal	1	no	-0.002	0.000	EPSD	ICGC;COSMIC	0.000	Gain
CMGC_MAPK_JNK_MAPK10_ST	O95644	NFATC1	P53779	MAPK10	S211	P208S	208	Missense	distal	-3	no	0.023	0.022	EPSD	ICGC	0.000	Down-regulation
CMGC_MAPK_JNK_MAPK10_ST	O95644	NFATC1	P53779	MAPK10	S211	P208L	208	Missense	distal	-3	no	0.023	0.022	EPSD	ICGC;COSMIC	0.000	Down-regulation
CMGC_MAPK_JNK_MAPK10_ST	O95644	NFATC1	P53779	MAPK10	S233	P234L	234	Missense	proximal	1	no	0.023	-0.002	EPSD	ICGC;COSMIC	0.000	Loss
CMGC_MAPK_JNK_MAPK10_ST	O95644	NFATC1	P53779	MAPK10	S241	P242S	242	Missense	proximal	1	no	0.024	-0.003	EPSD	ICGC;COSMIC	0.000	Loss
CMGC_MAPK_JNK_MAPK10_ST	O95644	NFATC1	P53779	MAPK10	S241	P242L	242	Missense	proximal	1	no	0.024	-0.002	EPSD	ICGC;COSMIC	0.000	Loss
CMGC_MAPK_JNK_MAPK10_ST	O95644	NFATC1	P53779	MAPK10	S261	P262L	262	Missense	proximal	1	no	0.023	-0.002	EPSD	ICGC;COSMIC	0.000	Loss
CMGC_MAPK_JNK_MAPK10_ST	O95644	NFATC1	P53779	MAPK10	S278	P276A	276	Missense	proximal	-2	no	0.024	0.023	EPSD	ICGC;COSMIC	0.000	Down-regulation
CMGC_MAPK_JNK_MAPK10_ST	O95644	NFATC1	P53779	MAPK10	S286	S286P	286	Missense	central	0	yes	0.023	0.000	EPSD	ICGC;COSMIC	0.000	Loss
CMGC_MAPK_JNK_MAPK10_ST	O95644	NFATC1	P53779	MAPK10	S290	S290F	290	Missense	central	0	yes	0.023	0.000	EPSD	ICGC;COSMIC	0.000	Loss
CMGC_MAPK_JNK_MAPK10_ST	O95644	NFATC1	P53779	MAPK10	S290	P291T	291	Missense	proximal	1	no	0.023	-0.002	EPSD	ICGC;COSMIC	0.000	Loss
CMGC_MAPK_JNK_MAPK10_ST	O95644	NFATC1	P53779	MAPK10	S294	V295M	295	Missense	proximal	1	no	-0.001	0.000	EPSD	ICGC	0.000	Gain
CMGC_MAPK_JNK_MAPK10_ST	O95644	NFATC1	P53779	MAPK10	S335	P332S	332	Missense	distal	-3	no	0.000	-0.001	EPSD	ICGC;COSMIC	0.000	Loss
CMGC_MAPK_JNK_MAPK10_ST	O95644	NFATC1	P53779	MAPK10	S335	R336S	336	Missense	proximal	1	no	0.000	-0.002	EPSD	ICGC;COSMIC	0.000	Loss
CMGC_MAPK_JNK_MAPK10_ST	O95644	NFATC1	P53779	MAPK10	S403	P404S	404	Missense	proximal	1	no	0.023	-0.003	EPSD	ICGC;COSMIC	0.000	Loss
CMGC_MAPK_JNK_MAPK10_ST	O95644	NFATC1	P53779	MAPK10	S406	P404S	404	Missense	proximal	-2	no	0.001	0.000	EPSD	ICGC;COSMIC	0.000	Down-regulation
CMGC_MAPK_JNK_MAPK10_ST	O95644	NFATC1	P53779	MAPK10	S409	P410T	410	Missense	proximal	1	no	0.023	-0.002	EPSD	ICGC;COSMIC	0.000	Loss
CMGC_MAPK_JNK_MAPK10_ST	O95644	NFATC1	P53779	MAPK10	S409	S409R	409	Missense	central	0	yes	0.023	0.000	EPSD	ICGC;COSMIC	0.000	Loss
CMGC_MAPK_JNK_MAPK10_ST	O95644	NFATC1	P53779	MAPK10	S617	G618C	618	Missense	proximal	1	no	-0.002	0.000	EPSD	ICGC;COSMIC	0.000	Gain
CMGC_MAPK_JNK_MAPK10_ST	O95644	NFATC1	P53779	MAPK10	S670	S670N	670	Missense	central	0	yes	0.023	0.000	EPSD	ICGC;COSMIC	0.000	Loss
CMGC_MAPK_JNK_MAPK10_ST	O95644	NFATC1	P53779	MAPK10	T889	A890D	890	Missense	proximal	1	no	-0.002	0.000	EPSD	ICGC;COSMIC	0.000	Gain
CMGC_MAPK_JNK_MAPK10_ST	O95644	NFATC1	P53779	MAPK10	T912	P910L	910	Missense	proximal	-2	no	0.000	-0.001	EPSD	ICGC;COSMIC	0.000	Loss
Other_NEK_NEK1_NEK1_ST	P40337	VHL	Q96PY6	NEK1	T100	P95L	95	Missense	distal	-5	no	4.611	4.628	EPSD;PhosphoSitePlus	ICGC;COSMIC	2.106	Up-regulation
Other_NEK_NEK1_NEK1_ST	P40337	VHL	Q96PY6	NEK1	T100	E94D	94	Missense	distal	-6	no	4.611	4.704	EPSD;PhosphoSitePlus	ICGC;COSMIC	2.106	Up-regulation
Other_NEK_NEK1_NEK1_ST	P40337	VHL	Q96PY6	NEK1	T100	L101P	101	Missense	proximal	1	no	4.611	4.585	EPSD;PhosphoSitePlus	ICGC;COSMIC	2.106	Down-regulation
Other_NEK_NEK1_NEK1_ST	P40337	VHL	Q96PY6	NEK1	T100	Y98D	98	Missense	proximal	-2	no	4.611	4.603	EPSD;PhosphoSitePlus	ICGC;COSMIC	2.106	Down-regulation
Other_NEK_NEK1_NEK1_ST	P40337	VHL	Q96PY6	NEK1	T100	T105R	105	Missense	distal	5	no	4.611	4.536	EPSD;PhosphoSitePlus	ICGC;COSMIC	2.106	Down-regulation
Other_NEK_NEK1_NEK1_ST	P40337	VHL	Q96PY6	NEK1	T105	L101P	101	Missense	distal	-4	no	4.846	4.934	PhosphoSitePlus;EPSD	ICGC;COSMIC	2.106	Up-regulation
Other_NEK_NEK1_NEK1_ST	P40337	VHL	Q96PY6	NEK1	T105	I109N	109	Missense	distal	4	no	4.846	4.479	PhosphoSitePlus;EPSD	ICGC;COSMIC	2.106	Down-regulation
Other_NEK_NEK1_NEK1_ST	P40337	VHL	Q96PY6	NEK1	T105	Y112C	112	Missense	distal	7	no	4.846	4.863	PhosphoSitePlus;EPSD	ICGC;COSMIC	2.106	Up-regulation
Other_NEK_NEK1_NEK1_ST	P40337	VHL	Q96PY6	NEK1	T105	S111R	111	Missense	distal	6	no	4.846	4.856	PhosphoSitePlus;EPSD	ICGC;COSMIC	2.106	Up-regulation
Other_NEK_NEK1_NEK1_ST	P40337	VHL	Q96PY6	NEK1	T105	S111G	111	Missense	distal	6	no	4.846	4.793	PhosphoSitePlus;EPSD	ICGC;COSMIC	2.106	Down-regulation
Other_NEK_NEK1_NEK1_ST	P40337	VHL	Q96PY6	NEK1	T105	S111I	111	Missense	distal	6	no	4.846	4.703	PhosphoSitePlus;EPSD	ICGC;COSMIC;CCLE	2.106	Down-regulation
Other_NEK_NEK1_NEK1_ST	P40337	VHL	Q96PY6	NEK1	T105	Y98D	98	Missense	distal	-7	no	4.846	4.929	PhosphoSitePlus;EPSD	ICGC;COSMIC	2.106	Up-regulation
Other_NEK_NEK1_NEK1_ST	P40337	VHL	Q96PY6	NEK1	T105	T105R	105	Missense	central	0	yes	4.846	0.000	PhosphoSitePlus;EPSD	ICGC;COSMIC	2.106	Loss
Other_NEK_NEK1_NEK1_ST	P40337	VHL	Q96PY6	NEK1	S168	C162F	162	Missense	distal	-6	no	4.486	4.470	EPSD;PhosphoSitePlus	ICGC;COSMIC	2.106	Down-regulation
Other_NEK_NEK1_NEK1_ST	P40337	VHL	Q96PY6	NEK1	S168	R167L	167	Missense	proximal	-1	no	4.486	4.645	EPSD;PhosphoSitePlus	ICGC;COSMIC	2.106	Up-regulation
Other_NEK_NEK1_NEK1_ST	P40337	VHL	Q96PY6	NEK1	T202	Q203L	203	Missense	proximal	1	no	3.643	3.770	EPSD;PhosphoSitePlus	ICGC	2.106	Up-regulation
Other_NEK_NEK1_NEK1_ST	Q92698	RAD54L	Q96PY6	NEK1	S176	R172C	172	Missense	distal	-4	no	2.052	2.136	EPSD	ICGC;COSMIC;GDSC;CCLE	2.106	Gain
Other_NEK_NEK1_NEK1_ST	Q92698	RAD54L	Q96PY6	NEK1	S572	M570I	570	Missense	proximal	-2	no	4.189	4.235	PhosphoSitePlus	ICGC	2.106	Up-regulation
Other_NEK_NEK1_NEK1_ST	O14777	NDC80	Q96PY6	NEK1	T34	T31I	31	Missense	distal	-3	no	2.401	2.490	EPSD	ICGC;COSMIC	2.106	Up-regulation
CMGC_CDK_CCRK_CDK20_ST	P24941	CDK2	Q8IZL9	CDK20	T160	R157W	157	Missense	distal	-3	no	5.811	5.815	PhosphoSitePlus	ICGC;COSMIC	1.958	Up-regulation
CMGC_CDK_CCRK_CDK20_ST	P24941	CDK2	Q8IZL9	CDK20	T160	R157L	157	Missense	distal	-3	no	5.811	5.821	PhosphoSitePlus	ICGC;COSMIC	1.958	Up-regulation
TK_Axl_AXL_Y	Q92556	ELMO1	P30530	AXL	Y720	Y720C	720	Missense	central	0	yes	0.006	0.000	PhosphoSitePlus;EPSD	ICGC	0.002	Loss
TK_Axl_AXL_Y	P07948	LYN	P30530	AXL	Y32	S38A	38	Missense	distal	6	no	0.002	0.001	EPSD	ICGC	0.002	Loss
TK_Axl_AXL_Y	P07948	LYN	P30530	AXL	Y306	V303L	303	Missense	distal	-3	no	0.003	0.002	EPSD	ICGC;COSMIC	0.002	Down-regulation
TK_Axl_AXL_Y	P07948	LYN	P30530	AXL	Y492	D491G	491	Missense	proximal	-1	no	0.003	0.004	EPSD	ICGC;COSMIC	0.002	Up-regulation
TK_Axl_AXL_Y	P31749	AKT1	P30530	AXL	Y326	D325E	325	Missense	proximal	-1	no	0.003	0.004	EPSD	ICGC	0.002	Up-regulation
TK_Axl_AXL_Y	P42229	STAT5A	P30530	AXL	Y114	L113P	113	Missense	proximal	-1	no	0.002	0.001	EPSD	ICGC;COSMIC	0.002	Loss
TK_Axl_AXL_Y	P51692	STAT5B	P30530	AXL	Y682	P687S	687	Missense	distal	5	no	0.001	0.002	EPSD	ICGC;COSMIC	0.002	Gain
TK_Axl_AXL_Y	P40763	STAT3	P30530	AXL	Y705	A702T	702	Missense	distal	-3	no	0.006	0.005	PhosphoSitePlus	ICGC;COSMIC	0.002	Down-regulation
TK_Axl_AXL_Y	P06241	FYN	P30530	AXL	Y39	P36T	36	Missense	distal	-3	no	0.002	0.001	EPSD	ICGC;COSMIC	0.002	Loss
CAMK_DAPK_DAPK_DAPK3_ST	Q96A00	PPP1R14A	O43293	DAPK3	S12	R9C	9	Missense	distal	-3	no	7.400	1.296	PhosphoSitePlus;EPSD	ICGC	6.449	Loss
CAMK_DAPK_DAPK_DAPK3_ST	Q96A00	PPP1R14A	O43293	DAPK3	S16	R21C	21	Missense	distal	5	no	8.680	8.366	EPSD	ICGC;COSMIC	6.449	Down-regulation
CAMK_DAPK_DAPK_DAPK3_ST	Q96A00	PPP1R14A	O43293	DAPK3	S16	R9C	9	Missense	distal	-7	no	8.680	6.754	EPSD	ICGC	6.449	Down-regulation
CAMK_DAPK_DAPK_DAPK3_ST	Q96A00	PPP1R14A	O43293	DAPK3	T38	Q31K	31	Missense	distal	-7	no	9.447	10.485	EPSD;PhosphoSitePlus	ICGC	6.449	Up-regulation
CAMK_DAPK_DAPK_DAPK3_ST	Q96A00	PPP1R14A	O43293	DAPK3	T38	H34Y	34	Missense	distal	-4	no	9.447	9.244	EPSD;PhosphoSitePlus	ICGC;COSMIC	6.449	Down-regulation
CAMK_DAPK_DAPK_DAPK3_ST	Q96A00	PPP1R14A	O43293	DAPK3	T38	H34Q	34	Missense	distal	-4	no	9.447	9.614	EPSD;PhosphoSitePlus	ICGC	6.449	Up-regulation
CAMK_DAPK_DAPK_DAPK3_ST	Q96A00	PPP1R14A	O43293	DAPK3	T38	A35T	35	Missense	distal	-3	no	9.447	8.404	EPSD;PhosphoSitePlus	ICGC;COSMIC	6.449	Down-regulation
CAMK_DAPK_DAPK_DAPK3_ST	O43293	DAPK3	O43293	DAPK3	S50	R48L	48	Missense	proximal	-2	no	10.604	8.263	EPSD	ICGC;COSMIC	6.449	Down-regulation
CAMK_DAPK_DAPK_DAPK3_ST	O43293	DAPK3	O43293	DAPK3	S50	R47S	47	Missense	distal	-3	no	10.604	5.971	EPSD	ICGC	6.449	Loss
CAMK_DAPK_DAPK_DAPK3_ST	O43293	DAPK3	O43293	DAPK3	T112	A106V	106	Missense	distal	-6	no	6.081	6.592	EPSD	ICGC;COSMIC	6.449	Gain
CAMK_DAPK_DAPK_DAPK3_ST	O43293	DAPK3	O43293	DAPK3	T180	P186T	186	Missense	distal	6	no	9.757	9.743	EPSD;PhosphoSitePlus	ICGC	6.449	Down-regulation
CAMK_DAPK_DAPK_DAPK3_ST	O43293	DAPK3	O43293	DAPK3	T180	I177T	177	Missense	distal	-3	no	9.757	9.687	EPSD;PhosphoSitePlus	ICGC;COSMIC	6.449	Down-regulation
CAMK_DAPK_DAPK_DAPK3_ST	O43293	DAPK3	O43293	DAPK3	T265	R262Q	262	Missense	distal	-3	no	12.236	8.104	EPSD;PhosphoSitePlus	ICGC;COSMIC	6.449	Down-regulation
CAMK_DAPK_DAPK_DAPK3_ST	O43293	DAPK3	O43293	DAPK3	T265	S269R	269	Missense	distal	4	no	12.236	12.207	EPSD;PhosphoSitePlus	ICGC	6.449	Down-regulation
CAMK_DAPK_DAPK_DAPK3_ST	O43293	DAPK3	O43293	DAPK3	T265	P260L	260	Missense	distal	-5	no	12.236	11.146	EPSD;PhosphoSitePlus	ICGC	6.449	Down-regulation
CAMK_DAPK_DAPK_DAPK3_ST	O43293	DAPK3	O43293	DAPK3	T306	H310F	310	Missense	distal	4	no	11.911	11.945	PhosphoSitePlus;EPSD	ICGC	6.449	Up-regulation
CAMK_DAPK_DAPK_DAPK3_ST	O43293	DAPK3	O43293	DAPK3	T306	H310Y	310	Missense	distal	4	no	11.911	11.942	PhosphoSitePlus;EPSD	ICGC	6.449	Up-regulation
CAMK_DAPK_DAPK_DAPK3_ST	O43293	DAPK3	O43293	DAPK3	T306	H310L	310	Missense	distal	4	no	11.911	11.904	PhosphoSitePlus;EPSD	ICGC	6.449	Down-regulation
CAMK_DAPK_DAPK_DAPK3_ST	O43293	DAPK3	O43293	DAPK3	S311	P314L	314	Missense	distal	3	no	11.084	10.923	EPSD;PhosphoSitePlus	ICGC;COSMIC	6.449	Down-regulation
CAMK_DAPK_DAPK_DAPK3_ST	O43293	DAPK3	O43293	DAPK3	S311	N316K	316	Missense	distal	5	no	11.084	11.170	EPSD;PhosphoSitePlus	ICGC	6.449	Up-regulation
CAMK_DAPK_DAPK_DAPK3_ST	O43293	DAPK3	O43293	DAPK3	S311	H310F	310	Missense	proximal	-1	no	11.084	11.132	EPSD;PhosphoSitePlus	ICGC	6.449	Up-regulation
CAMK_DAPK_DAPK_DAPK3_ST	O43293	DAPK3	O43293	DAPK3	S311	H310Y	310	Missense	proximal	-1	no	11.084	11.180	EPSD;PhosphoSitePlus	ICGC	6.449	Up-regulation
CAMK_DAPK_DAPK_DAPK3_ST	O43293	DAPK3	O43293	DAPK3	S311	H310L	310	Missense	proximal	-1	no	11.084	11.070	EPSD;PhosphoSitePlus	ICGC	6.449	Down-regulation
CAMK_DAPK_DAPK_DAPK3_ST	Q00987	MDM2	O43293	DAPK3	T47	K45N	45	Missense	proximal	-2	no	6.776	6.017	EPSD	ICGC	6.449	Loss
CAMK_DAPK_DAPK_DAPK3_ST	Q00987	MDM2	O43293	DAPK3	T47	K45R	45	Missense	proximal	-2	no	6.776	8.014	EPSD	ICGC	6.449	Up-regulation
CAMK_DAPK_DAPK_DAPK3_ST	Q00987	MDM2	O43293	DAPK3	S186	S190C	190	Missense	distal	4	no	11.436	11.482	EPSD;PhosphoSitePlus	ICGC;COSMIC	6.449	Up-regulation
CAMK_DAPK_DAPK_DAPK3_ST	Q00987	MDM2	O43293	DAPK3	T419	V426F	426	Missense	distal	7	no	7.625	7.673	EPSD	ICGC	6.449	Up-regulation
CAMK_DAPK_DAPK_DAPK3_ST	P40429	RPL13A	O43293	DAPK3	T64	Y71D	71	Missense	distal	7	no	9.982	10.008	EPSD	ICGC	6.449	Up-regulation
CAMK_DAPK_DAPK_DAPK3_ST	P40429	RPL13A	O43293	DAPK3	T64	P66S	66	Missense	proximal	2	no	9.982	9.924	EPSD	ICGC;COSMIC	6.449	Down-regulation
CAMK_DAPK_DAPK_DAPK3_ST	P40429	RPL13A	O43293	DAPK3	T64	R59S	59	Missense	distal	-5	no	9.982	8.051	EPSD	ICGC;COSMIC	6.449	Down-regulation
CAMK_DAPK_DAPK_DAPK3_ST	P40429	RPL13A	O43293	DAPK3	S77	P76S	76	Missense	proximal	-1	no	11.310	11.265	PhosphoSitePlus	ICGC;COSMIC	6.449	Down-regulation
CAMK_DAPK_DAPK_DAPK3_ST	P40429	RPL13A	O43293	DAPK3	S77	Y71D	71	Missense	distal	-6	no	11.310	11.347	PhosphoSitePlus	ICGC	6.449	Up-regulation
CAMK_DAPK_DAPK_DAPK3_ST	O14950	MYL12B	O43293	DAPK3	T19	T19A	19	Missense	central	0	yes	10.367	0.000	EPSD;PhosphoSitePlus	ICGC;COSMIC	6.449	Loss
CAMK_DAPK_DAPK_DAPK3_ST	O14950	MYL12B	O43293	DAPK3	S20	T19A	19	Missense	proximal	-1	no	11.851	11.893	PhosphoSitePlus;EPSD	ICGC;COSMIC	6.449	Up-regulation
CAMK_DAPK_DAPK_DAPK3_ST	P04637	TP53	O43293	DAPK3	S127	C124R	124	Missense	distal	-3	no	1.771	7.875	EPSD	ICGC;COSMIC;GDSC;CCLE	6.449	Gain
CAMK_DAPK_DAPK_DAPK3_ST	P38936	CDKN1A	O43293	DAPK3	S31	S31R	31	Missense	central	0	yes	6.680	0.000	EPSD	ICGC;COSMIC	6.449	Loss
CAMK_DAPK_DAPK_DAPK3_ST	P38936	CDKN1A	O43293	DAPK3	S31	R32L	32	Missense	proximal	1	no	6.680	6.729	EPSD	ICGC	6.449	Up-regulation
CAMK_DAPK_DAPK_DAPK3_ST	P38936	CDKN1A	O43293	DAPK3	S31	E28K	28	Missense	distal	-3	no	6.680	7.722	EPSD	ICGC;COSMIC	6.449	Up-regulation
CAMK_DAPK_DAPK_DAPK3_ST	P38936	CDKN1A	O43293	DAPK3	T145	R143L	143	Missense	proximal	-2	no	14.198	11.857	PhosphoSitePlus	ICGC	6.449	Down-regulation
CAMK_DAPK_DAPK_DAPK3_ST	P38936	CDKN1A	O43293	DAPK3	T145	R142Q	142	Missense	distal	-3	no	14.198	10.066	PhosphoSitePlus	ICGC	6.449	Down-regulation
CAMK_DAPK_DAPK_DAPK3_ST	P38936	CDKN1A	O43293	DAPK3	T145	R140Q	140	Missense	distal	-5	no	14.198	12.214	PhosphoSitePlus	ICGC;COSMIC	6.449	Down-regulation
CAMK_DAPK_DAPK_DAPK3_ST	P38936	CDKN1A	O43293	DAPK3	S146	R143L	143	Missense	distal	-3	no	6.558	1.018	EPSD	ICGC	6.449	Loss
CAMK_DAPK_DAPK_DAPK3_ST	P38936	CDKN1A	O43293	DAPK3	S146	R142Q	142	Missense	distal	-4	no	6.558	6.343	EPSD	ICGC	6.449	Loss
CAMK_DAPK_DAPK_DAPK3_ST	P38936	CDKN1A	O43293	DAPK3	S146	R140Q	140	Missense	distal	-6	no	6.558	7.153	EPSD	ICGC;COSMIC	6.449	Up-regulation
CAMK_DAPK_DAPK_DAPK3_ST	Q14457	BECN1	O43293	DAPK3	S90	P85Q	85	Missense	distal	-5	no	10.465	10.233	PhosphoSitePlus	ICGC	6.449	Down-regulation
CAMK_DAPK_DAPK_DAPK3_ST	Q14457	BECN1	O43293	DAPK3	T91	P85Q	85	Missense	distal	-6	no	7.709	7.599	EPSD	ICGC	6.449	Down-regulation
CAMK_DAPK_DAPK_DAPK3_ST	Q14457	BECN1	O43293	DAPK3	T98	D105N	105	Missense	distal	7	no	7.390	7.252	EPSD	ICGC	6.449	Down-regulation
CAMK_DAPK_DAPK_DAPK3_ST	Q14457	BECN1	O43293	DAPK3	T98	A103E	103	Missense	distal	5	no	7.390	7.388	EPSD	ICGC	6.449	Down-regulation
CAMK_DAPK_DAPK_DAPK3_ST	Q14457	BECN1	O43293	DAPK3	S337	G334R	334	Missense	distal	-3	no	4.042	9.043	EPSD	ICGC;COSMIC	6.449	Gain
TK_FGFR_FGFR2_Y	P21802	FGFR2	P21802	FGFR2	Y769	E768K	768	Missense	proximal	-1	no	2.917	2.724	PhosphoSitePlus	ICGC;COSMIC	1.189	Down-regulation
TK_FGFR_FGFR2_Y	P21802	FGFR2	P21802	FGFR2	Y769	P775L	775	Missense	distal	6	no	2.917	2.522	PhosphoSitePlus	ICGC;COSMIC	1.189	Down-regulation
TK_FGFR_FGFR2_Y	P60484	PTEN	P21802	FGFR2	Y240	P244R	244	Missense	distal	4	no	3.649	3.674	PhosphoSitePlus	ICGC;COSMIC	1.189	Up-regulation
TK_FGFR_FGFR2_Y	P62993	GRB2	P21802	FGFR2	Y7	D14E	14	Missense	distal	7	no	1.633	1.656	EPSD	ICGC	1.189	Up-regulation
CAMK_CAMKL_BRSK_BRSK1_ST	Q8TDC3	BRSK1	Q8TDC3-2	BRSK1	T189	G192C	192	Missense	distal	3	no	1.236	1.193	EPSD	ICGC;COSMIC	0.579	Down-regulation
CAMK_CAMKL_BRSK_BRSK1_ST	Q8TDC3	BRSK1	Q8TDC3-2	BRSK1	T189	V182M	182	Missense	distal	-7	no	1.236	1.229	EPSD	ICGC	0.579	Down-regulation
CAMK_CAMKL_BRSK_BRSK1_ST	Q8TDC3	BRSK1	Q8TDC3-2	BRSK1	S193	G192C	192	Missense	proximal	-1	no	1.181	1.158	EPSD	ICGC;COSMIC	0.579	Down-regulation
CAMK_CAMKL_BRSK_BRSK1_ST	Q8TDC3	BRSK1	Q8TDC3-2	BRSK1	S275	S275C	275	Missense	central	0	yes	0.690	0.000	EPSD	ICGC;COSMIC	0.579	Loss
CAMK_CAMKL_BRSK_BRSK1_ST	Q13131	PRKAA1	Q8TDC3-2	BRSK1	T183	N189S	189	Missense	distal	6	no	1.202	1.127	PhosphoSitePlus	ICGC;COSMIC;CCLE	0.579	Down-regulation
CAMK_CAMKL_BRSK_BRSK1_ST	Q13131	PRKAA1	Q8TDC3-2	BRSK1	T183	T183K	183	Missense	central	0	yes	1.202	0.000	PhosphoSitePlus	ICGC	0.579	Loss
CAMK_CAMKL_BRSK_BRSK1_ST	Q13131	PRKAA1	Q8TDC3-2	BRSK1	S187	N189S	189	Missense	proximal	2	no	0.707	0.709	EPSD	ICGC;COSMIC;CCLE	0.579	Up-regulation
CAMK_CAMKL_BRSK_BRSK1_ST	Q13131	PRKAA1	Q8TDC3-2	BRSK1	S295	E290D	290	Missense	distal	-5	no	0.662	0.631	EPSD	ICGC;COSMIC	0.579	Down-regulation
CAMK_CAMKL_BRSK_BRSK1_ST	Q13131	PRKAA1	Q8TDC3-2	BRSK1	S295	M298I	298	Missense	distal	3	no	0.662	0.635	EPSD	ICGC;COSMIC	0.579	Down-regulation
CAMK_CAMKL_BRSK_BRSK1_ST	Q13131	PRKAA1	Q8TDC3-2	BRSK1	S467	V465L	465	Missense	proximal	-2	no	0.697	0.788	EPSD	ICGC;COSMIC	0.579	Up-regulation
CAMK_CAMKL_BRSK_BRSK1_ST	Q13131	PRKAA1	Q8TDC3-2	BRSK1	S467	Q464K	464	Missense	distal	-3	no	0.697	0.702	EPSD	ICGC;COSMIC	0.579	Up-regulation
CAMK_CAMKL_BRSK_BRSK1_ST	Q13131	PRKAA1	Q8TDC3-2	BRSK1	S496	S498C	498	Missense	proximal	2	no	0.657	0.669	EPSD	ICGC;COSMIC	0.579	Up-regulation
CAMK_CAMKL_BRSK_BRSK1_ST	Q13131	PRKAA1	Q8TDC3-2	BRSK1	S496	R501P	501	Missense	distal	5	no	0.657	0.680	EPSD	ICGC;COSMIC	0.579	Up-regulation
CAMK_CAMKL_BRSK_BRSK1_ST	Q13131	PRKAA1	Q8TDC3-2	BRSK1	S496	C503Y	503	Missense	distal	7	no	0.657	0.656	EPSD	ICGC	0.579	Down-regulation
CAMK_CAMKL_BRSK_BRSK1_ST	Q13131	PRKAA1	Q8TDC3-2	BRSK1	S496	Y500C	500	Missense	distal	4	no	0.657	0.665	EPSD	ICGC;COSMIC	0.579	Up-regulation
CAMK_CAMKL_BRSK_BRSK1_ST	Q13131	PRKAA1	Q8TDC3-2	BRSK1	S523	S530C	530	Missense	distal	7	no	0.695	0.691	EPSD	ICGC;COSMIC	0.579	Down-regulation
CAMK_CAMKL_BRSK_BRSK1_ST	Q13131	PRKAA1	Q8TDC3-2	BRSK1	S523	S524Y	524	Missense	proximal	1	no	0.695	0.597	EPSD	ICGC;COSMIC	0.579	Down-regulation
CAMK_CAMKL_BRSK_BRSK1_ST	Q13131	PRKAA1	Q8TDC3-2	BRSK1	T526	S530C	530	Missense	distal	4	no	0.642	0.632	EPSD	ICGC;COSMIC	0.579	Down-regulation
CAMK_CAMKL_BRSK_BRSK1_ST	Q13131	PRKAA1	Q8TDC3-2	BRSK1	T526	S524Y	524	Missense	proximal	-2	no	0.642	0.503	EPSD	ICGC;COSMIC	0.579	Loss
CAMK_CAMKL_BRSK_BRSK1_ST	Q13131	PRKAA1	Q8TDC3-2	BRSK1	S527	S530C	530	Missense	distal	3	no	0.676	0.688	EPSD	ICGC;COSMIC	0.579	Up-regulation
CAMK_CAMKL_BRSK_BRSK1_ST	Q13131	PRKAA1	Q8TDC3-2	BRSK1	S527	S524Y	524	Missense	distal	-3	no	0.676	0.666	EPSD	ICGC;COSMIC	0.579	Down-regulation
CAMK_CAMKL_BRSK_BRSK1_ST	Q13131	PRKAA1	Q8TDC3-2	BRSK1	S530	S530C	530	Missense	central	0	yes	0.688	0.000	EPSD	ICGC;COSMIC	0.579	Loss
CAMK_CAMKL_BRSK_BRSK1_ST	Q13131	PRKAA1	Q8TDC3-2	BRSK1	S530	S524Y	524	Missense	distal	-6	no	0.688	0.656	EPSD	ICGC;COSMIC	0.579	Down-regulation
CAMK_CAMKL_BRSK_BRSK1_ST	P30291	WEE1	Q8TDC3-2	BRSK1	S205	D202Y	202	Missense	distal	-3	no	0.797	0.800	EPSD	ICGC;COSMIC	0.579	Up-regulation
CAMK_CAMKL_BRSK_BRSK1_ST	P30291	WEE1	Q8TDC3-2	BRSK1	S205	G210C	210	Missense	distal	5	no	0.797	0.770	EPSD	ICGC;COSMIC	0.579	Down-regulation
CAMK_CAMKL_BRSK_BRSK1_ST	P30291	WEE1	Q8TDC3-2	BRSK1	S592	E587K	587	Missense	distal	-5	no	0.585	0.552	EPSD	ICGC;COSMIC	0.579	Loss
CAMK_CAMKL_BRSK_BRSK1_ST	P30291	WEE1	Q8TDC3-2	BRSK1	S642	R639C	639	Missense	distal	-3	no	0.793	0.785	PhosphoSitePlus	ICGC;COSMIC	0.579	Down-regulation
CAMK_CAMKL_BRSK_BRSK1_ST	P30291	WEE1	Q8TDC3-2	BRSK1	S642	S642I	642	Missense	central	0	yes	0.793	0.000	PhosphoSitePlus	ICGC;COSMIC	0.579	Loss
CAMK_CAMKL_BRSK_BRSK1_ST	P23258	TUBG1	Q8TDC3-2	BRSK1	S131	C138F	138	Missense	distal	7	no	1.301	1.291	PhosphoSitePlus	ICGC	0.579	Down-regulation
CAMK_CAMKL_BRSK_BRSK1_ST	P23258	TUBG1	Q8TDC3-2	BRSK1	S131	R124Q	124	Missense	distal	-7	no	1.301	1.306	PhosphoSitePlus	ICGC;COSMIC	0.579	Up-regulation
CAMK_CAMKL_BRSK_BRSK1_ST	P23258	TUBG1	Q8TDC3-2	BRSK1	S131	R124L	124	Missense	distal	-7	no	1.301	1.310	PhosphoSitePlus	ICGC;COSMIC	0.579	Up-regulation
CAMK_CAMKL_BRSK_BRSK1_ST	P23258	TUBG1	Q8TDC3-2	BRSK1	S306	R311L	311	Missense	distal	5	no	0.575	0.632	EPSD	ICGC	0.579	Gain
CAMK_CAMKL_BRSK_BRSK1_ST	P23258	TUBG1	Q8TDC3-2	BRSK1	S385	S386L	386	Missense	proximal	1	no	1.207	1.160	EPSD	ICGC;COSMIC	0.579	Down-regulation
CAMK_CAMKL_BRSK_BRSK1_ST	P23258	TUBG1	Q8TDC3-2	BRSK1	S385	A379D	379	Missense	distal	-6	no	1.207	1.256	EPSD	ICGC	0.579	Up-regulation
CAMK_CAMKL_BRSK_BRSK1_ST	P30305	CDC25B	Q8TDC3-2	BRSK1	S115	D120Y	120	Missense	distal	5	no	0.711	0.702	EPSD	ICGC	0.579	Down-regulation
CAMK_CAMKL_BRSK_BRSK1_ST	P30305	CDC25B	Q8TDC3-2	BRSK1	S323	M324R	324	Missense	proximal	1	no	0.747	0.725	EPSD	ICGC;COSMIC	0.579	Down-regulation
CAMK_CAMKL_BRSK_BRSK1_ST	P30305	CDC25B	Q8TDC3-2	BRSK1	S323	R320C	320	Missense	distal	-3	no	0.747	0.739	EPSD	ICGC	0.579	Down-regulation
CAMK_CAMKL_BRSK_BRSK1_ST	P30305	CDC25B	Q8TDC3-2	BRSK1	S375	E382G	382	Missense	distal	7	no	1.213	1.196	PhosphoSitePlus	ICGC;COSMIC	0.579	Down-regulation
CAMK_CAMKL_BRSK_BRSK1_ST	P30305	CDC25B	Q8TDC3-2	BRSK1	S397	A399T	399	Missense	proximal	2	no	0.696	0.683	EPSD	ICGC;COSMIC	0.579	Down-regulation
CAMK_CAMKL_BRSK_BRSK1_ST	P30305	CDC25B	Q8TDC3-2	BRSK1	S397	A399G	399	Missense	proximal	2	no	0.696	0.679	EPSD	ICGC;COSMIC	0.579	Down-regulation
CAMK_CAMKL_BRSK_BRSK1_ST	P30307	CDC25C	Q8TDC3-2	BRSK1	S168	T172A	172	Missense	distal	4	no	0.633	0.639	EPSD	ICGC;COSMIC	0.579	Up-regulation
CAMK_CAMKL_BRSK_BRSK1_ST	P30307	CDC25C	Q8TDC3-2	BRSK1	T172	T172A	172	Missense	central	0	yes	0.767	0.000	EPSD	ICGC;COSMIC	0.579	Loss
CAMK_CAMKL_BRSK_BRSK1_ST	P30307	CDC25C	Q8TDC3-2	BRSK1	S207	Q202K	202	Missense	distal	-5	no	0.747	0.782	EPSD	ICGC	0.579	Up-regulation
CAMK_CAMKL_BRSK_BRSK1_ST	P30307	CDC25C	Q8TDC3-2	BRSK1	S216	E219D	219	Missense	distal	3	no	1.279	1.292	PhosphoSitePlus	ICGC;COSMIC	0.579	Up-regulation
CAMK_CAMKL_BRSK_BRSK1_ST	P30307	CDC25C	Q8TDC3-2	BRSK1	S451	G456V	456	Missense	distal	5	no	0.689	0.657	EPSD	ICGC;COSMIC	0.579	Down-regulation
TK_Ack_TNK2_Y	P42768	WAS	Q07912	TNK2	Y102	Y102H	102	Missense	central	0	yes	0.000	0.000	EPSD	ICGC;COSMIC	0.000	Loss
AGC_Akt_AKT3_ST	Q96ST2	IWS1	Q9Y243	AKT3	S54	N51K	51	Missense	distal	-3	no	1.993	3.010	EPSD	ICGC	2.840	Gain
AGC_Akt_AKT3_ST	Q96ST2	IWS1	Q9Y243	AKT3	S159	K166N	166	Missense	distal	7	no	2.583	2.862	EPSD	ICGC;COSMIC	2.840	Gain
AGC_Akt_AKT3_ST	Q96ST2	IWS1	Q9Y243	AKT3	S415	R412H	412	Missense	distal	-3	no	3.508	1.195	EPSD	ICGC;COSMIC	2.840	Loss
AGC_Akt_AKT3_ST	Q96ST2	IWS1	Q9Y243	AKT3	S440	A444E	444	Missense	distal	4	no	3.679	3.589	EPSD	ICGC	2.840	Down-regulation
AGC_Akt_AKT3_ST	Q96ST2	IWS1	Q9Y243	AKT3	S465	L472R	472	Missense	distal	7	no	3.133	2.847	EPSD	ICGC;COSMIC	2.840	Down-regulation
AGC_Akt_AKT3_ST	Q96ST2	IWS1	Q9Y243	AKT3	S513	N516S	516	Missense	distal	3	no	3.554	3.661	EPSD	ICGC	2.840	Up-regulation
AGC_Akt_AKT3_ST	Q96ST2	IWS1	Q9Y243	AKT3	T721	R728I	728	Missense	distal	7	no	2.900	3.046	PhosphoSitePlus;EPSD	ICGC;COSMIC	2.840	Up-regulation
AGC_Akt_AKT3_ST	Q96ST2	IWS1	Q9Y243	AKT3	T796	K800E	800	Missense	distal	4	no	3.579	3.540	EPSD	ICGC;COSMIC	2.840	Down-regulation
AGC_Akt_AKT3_ST	O15119	TBX3	Q9Y243	AKT3	S432	R427G	427	Missense	distal	-5	no	3.279	1.946	EPSD	ICGC;COSMIC	2.840	Loss
AGC_Akt_AKT3_ST	O15119	TBX3	Q9Y243	AKT3	S432	A431V	431	Missense	proximal	-1	no	3.279	2.530	EPSD	ICGC;COSMIC	2.840	Loss
AGC_Akt_AKT3_ST	O15119	TBX3	Q9Y243	AKT3	T698	S703I	703	Missense	distal	5	no	4.823	4.954	EPSD	ICGC;COSMIC	2.840	Up-regulation
AGC_Akt_AKT3_ST	O15119	TBX3	Q9Y243	AKT3	S700	S703I	703	Missense	distal	3	no	2.878	2.817	EPSD	ICGC;COSMIC	2.840	Loss
AGC_Akt_AKT3_ST	O15119	TBX3	Q9Y243	AKT3	S702	S703I	703	Missense	proximal	1	no	2.940	2.970	EPSD	ICGC;COSMIC	2.840	Up-regulation
AGC_Akt_AKT3_ST	P15056	BRAF	Q9Y243	AKT3	S335	P328F	328	Missense	distal	-7	no	3.225	3.212	EPSD	ICGC	2.840	Down-regulation
AGC_Akt_AKT3_ST	P15056	BRAF	Q9Y243	AKT3	S335	P334L	334	Missense	proximal	-1	no	3.225	3.202	EPSD	ICGC;COSMIC	2.840	Down-regulation
AGC_Akt_AKT3_ST	P15056	BRAF	Q9Y243	AKT3	S339	P334L	334	Missense	distal	-5	no	2.797	2.880	EPSD	ICGC;COSMIC	2.840	Gain
AGC_Akt_AKT3_ST	P15056	BRAF	Q9Y243	AKT3	S364	Q359R	359	Missense	distal	-5	no	2.410	3.597	EPSD	ICGC;COSMIC	2.840	Gain
AGC_Akt_AKT3_ST	P15056	BRAF	Q9Y243	AKT3	S365	N372K	372	Missense	distal	7	no	9.586	9.307	PhosphoSitePlus;EPSD	ICGC	2.840	Down-regulation
AGC_Akt_AKT3_ST	P15056	BRAF	Q9Y243	AKT3	S365	Q359K	359	Missense	distal	-6	no	9.586	9.569	PhosphoSitePlus;EPSD	ICGC	2.840	Down-regulation
AGC_Akt_AKT3_ST	P15056	BRAF	Q9Y243	AKT3	S365	S363F	363	Missense	proximal	-2	no	9.586	8.615	PhosphoSitePlus;EPSD	ICGC;COSMIC	2.840	Down-regulation
AGC_Akt_AKT3_ST	P15056	BRAF	Q9Y243	AKT3	S365	P367L	367	Missense	proximal	2	no	9.586	9.731	PhosphoSitePlus;EPSD	ICGC;COSMIC	2.840	Up-regulation
AGC_Akt_AKT3_ST	P15056	BRAF	Q9Y243	AKT3	S365	Q359R	359	Missense	distal	-6	no	9.586	9.613	PhosphoSitePlus;EPSD	ICGC;COSMIC	2.840	Up-regulation
AGC_Akt_AKT3_ST	P15056	BRAF	Q9Y243	AKT3	T411	A404D	404	Missense	distal	-7	no	2.951	2.838	EPSD	ICGC;COSMIC	2.840	Loss
AGC_Akt_AKT3_ST	P15056	BRAF	Q9Y243	AKT3	T411	L410Q	410	Missense	proximal	-1	no	2.951	2.839	EPSD	ICGC	2.840	Loss
AGC_Akt_AKT3_ST	P15056	BRAF	Q9Y243	AKT3	S429	S429Y	429	Missense	central	0	yes	8.364	0.000	EPSD;PhosphoSitePlus	ICGC	2.840	Loss
AGC_Akt_AKT3_ST	P15056	BRAF	Q9Y243	AKT3	S429	Q423H	423	Missense	distal	-6	no	8.364	8.339	EPSD;PhosphoSitePlus	ICGC;COSMIC	2.840	Down-regulation
AGC_Akt_AKT3_ST	P15056	BRAF	Q9Y243	AKT3	S429	S428T	428	Missense	proximal	-1	no	8.364	8.062	EPSD;PhosphoSitePlus	ICGC;COSMIC	2.840	Down-regulation
AGC_Akt_AKT3_ST	P15056	BRAF	Q9Y243	AKT3	S431	S429Y	429	Missense	proximal	-2	no	4.867	4.012	EPSD	ICGC	2.840	Down-regulation
AGC_Akt_AKT3_ST	P15056	BRAF	Q9Y243	AKT3	S431	M438I	438	Missense	distal	7	no	4.867	4.805	EPSD	ICGC;COSMIC	2.840	Down-regulation
AGC_Akt_AKT3_ST	P15056	BRAF	Q9Y243	AKT3	S431	S428T	428	Missense	distal	-3	no	4.867	5.007	EPSD	ICGC;COSMIC	2.840	Up-regulation
AGC_Akt_AKT3_ST	P15056	BRAF	Q9Y243	AKT3	T440	R444Q	444	Missense	distal	4	no	3.952	4.007	EPSD	ICGC;COSMIC	2.840	Up-regulation
AGC_Akt_AKT3_ST	P15056	BRAF	Q9Y243	AKT3	T440	R444W	444	Missense	distal	4	no	3.952	3.994	EPSD	ICGC;COSMIC	2.840	Up-regulation
AGC_Akt_AKT3_ST	P15056	BRAF	Q9Y243	AKT3	T440	T440K	440	Missense	central	0	yes	3.952	0.000	EPSD	ICGC	2.840	Loss
AGC_Akt_AKT3_ST	P15056	BRAF	Q9Y243	AKT3	T440	L441I	441	Missense	proximal	1	no	3.952	3.947	EPSD	ICGC;COSMIC	2.840	Down-regulation
AGC_Akt_AKT3_ST	P15056	BRAF	Q9Y243	AKT3	T440	S446L	446	Missense	distal	6	no	3.952	3.954	EPSD	ICGC;COSMIC	2.840	Up-regulation
AGC_Akt_AKT3_ST	P15056	BRAF	Q9Y243	AKT3	T440	M438I	438	Missense	proximal	-2	no	3.952	3.970	EPSD	ICGC;COSMIC	2.840	Up-regulation
AGC_Akt_AKT3_ST	P15056	BRAF	Q9Y243	AKT3	S446	R444Q	444	Missense	proximal	-2	no	4.270	4.080	EPSD	ICGC;COSMIC	2.840	Down-regulation
AGC_Akt_AKT3_ST	P15056	BRAF	Q9Y243	AKT3	S446	R444W	444	Missense	proximal	-2	no	4.270	4.209	EPSD	ICGC;COSMIC	2.840	Down-regulation
AGC_Akt_AKT3_ST	P15056	BRAF	Q9Y243	AKT3	S446	T440K	440	Missense	distal	-6	no	4.270	4.222	EPSD	ICGC	2.840	Down-regulation
AGC_Akt_AKT3_ST	P15056	BRAF	Q9Y243	AKT3	S446	L441I	441	Missense	distal	-5	no	4.270	4.172	EPSD	ICGC;COSMIC	2.840	Down-regulation
AGC_Akt_AKT3_ST	P15056	BRAF	Q9Y243	AKT3	S446	E451D	451	Missense	distal	5	no	4.270	4.420	EPSD	ICGC;COSMIC	2.840	Up-regulation
AGC_Akt_AKT3_ST	P15056	BRAF	Q9Y243	AKT3	S446	S446L	446	Missense	central	0	yes	4.270	0.000	EPSD	ICGC;COSMIC	2.840	Loss
AGC_Akt_AKT3_ST	P15056	BRAF	Q9Y243	AKT3	S447	R444Q	444	Missense	distal	-3	no	5.637	3.432	EPSD	ICGC;COSMIC	2.840	Down-regulation
AGC_Akt_AKT3_ST	P15056	BRAF	Q9Y243	AKT3	S447	R444W	444	Missense	distal	-3	no	5.637	2.971	EPSD	ICGC;COSMIC	2.840	Down-regulation
AGC_Akt_AKT3_ST	P15056	BRAF	Q9Y243	AKT3	S447	T440K	440	Missense	distal	-7	no	5.637	5.572	EPSD	ICGC	2.840	Down-regulation
AGC_Akt_AKT3_ST	P15056	BRAF	Q9Y243	AKT3	S447	L441I	441	Missense	distal	-6	no	5.637	5.786	EPSD	ICGC;COSMIC	2.840	Up-regulation
AGC_Akt_AKT3_ST	P15056	BRAF	Q9Y243	AKT3	S447	E451D	451	Missense	distal	4	no	5.637	5.649	EPSD	ICGC;COSMIC	2.840	Up-regulation
AGC_Akt_AKT3_ST	P15056	BRAF	Q9Y243	AKT3	S447	S446L	446	Missense	proximal	-1	no	5.637	4.671	EPSD	ICGC;COSMIC	2.840	Down-regulation
AGC_Akt_AKT3_ST	P15056	BRAF	Q9Y243	AKT3	S729	R726H	726	Missense	distal	-3	no	4.901	2.588	EPSD	ICGC;COSMIC	2.840	Loss
AGC_Akt_AKT3_ST	P15056	BRAF	Q9Y243	AKT3	S729	I724M	724	Missense	distal	-5	no	4.901	4.935	EPSD	ICGC	2.840	Up-regulation
AGC_Akt_AKT3_ST	P15056	BRAF	Q9Y243	AKT3	S729	E730D	730	Missense	proximal	1	no	4.901	4.894	EPSD	ICGC	2.840	Down-regulation
AGC_Akt_AKT3_ST	P15056	BRAF	Q9Y243	AKT3	S729	S727G	727	Missense	proximal	-2	no	4.901	3.976	EPSD	ICGC;COSMIC;GDSC;CCLE	2.840	Down-regulation
STE_STE11_MEKK1_MAP3K1_ST	P46531	NOTCH1	Q13233	MAP3K1	S900	A897D	897	Missense	distal	-3	no	2.321	1.689	EPSD	ICGC	2.285	Loss
STE_STE11_MEKK1_MAP3K1_ST	P46531	NOTCH1	Q13233	MAP3K1	S900	T906N	906	Missense	distal	6	no	2.321	2.302	EPSD	ICGC;COSMIC	2.285	Down-regulation
STE_STE11_MEKK1_MAP3K1_ST	P46531	NOTCH1	Q13233	MAP3K1	S900	C904S	904	Missense	distal	4	no	2.321	1.913	EPSD	ICGC;COSMIC	2.285	Loss
STE_STE11_MEKK1_MAP3K1_ST	P46531	NOTCH1	Q13233	MAP3K1	T1930	T1927M	1927	Missense	distal	-3	no	2.233	2.543	EPSD	ICGC;COSMIC;CCLE	2.285	Gain
STE_STE11_MEKK1_MAP3K1_ST	P46531	NOTCH1	Q13233	MAP3K1	T1997	G1995V	1995	Missense	proximal	-2	no	2.767	2.809	EPSD	ICGC;COSMIC	2.285	Up-regulation
STE_STE11_MEKK1_MAP3K1_ST	P46531	NOTCH1	Q13233	MAP3K1	T1997	L2001M	2001	Missense	distal	4	no	2.767	2.641	EPSD	ICGC	2.285	Down-regulation
STE_STE11_MEKK1_MAP3K1_ST	P46531	NOTCH1	Q13233	MAP3K1	T1997	T1996K	1996	Missense	proximal	-1	no	2.767	2.746	EPSD	ICGC	2.285	Down-regulation
STE_STE11_MEKK1_MAP3K1_ST	P46531	NOTCH1	Q13233	MAP3K1	T2132	H2125Q	2125	Missense	distal	-7	no	2.608	2.599	EPSD	ICGC;GDSC;CCLE	2.285	Down-regulation
STE_STE11_MEKK1_MAP3K1_ST	P46531	NOTCH1	Q13233	MAP3K1	T2132	G2130W	2130	Missense	proximal	-2	no	2.608	2.551	EPSD	ICGC;COSMIC	2.285	Down-regulation
STE_STE11_MEKK1_MAP3K1_ST	P46531	NOTCH1	Q13233	MAP3K1	T2132	P2138Q	2138	Missense	distal	6	no	2.608	2.411	EPSD	ICGC;COSMIC	2.285	Down-regulation
STE_STE11_MEKK1_MAP3K1_ST	P46531	NOTCH1	Q13233	MAP3K1	T2511	P2512L	2512	Missense	proximal	1	no	4.557	4.049	PhosphoSitePlus	ICGC;COSMIC	2.285	Down-regulation
STE_STE11_MEKK1_MAP3K1_ST	P46531	NOTCH1	Q13233	MAP3K1	T2511	S2516F	2516	Missense	distal	5	no	4.557	4.707	PhosphoSitePlus	ICGC	2.285	Up-regulation
STE_STE11_MEKK1_MAP3K1_ST	P46531	NOTCH1	Q13233	MAP3K1	T2511	P2512T	2512	Missense	proximal	1	no	4.557	4.042	PhosphoSitePlus	ICGC;COSMIC	2.285	Down-regulation
STE_STE11_MEKK1_MAP3K1_ST	P46531	NOTCH1	Q13233	MAP3K1	S2523	P2525Q	2525	Missense	proximal	2	no	2.117	2.565	EPSD	ICGC;COSMIC	2.285	Gain
STE_STE11_MEKK1_MAP3K1_ST	Q8NHW3	MAFA	Q13233	MAP3K1	T53	S56N	56	Missense	distal	3	no	2.714	2.758	EPSD	ICGC;COSMIC	2.285	Up-regulation
STE_STE11_MEKK1_MAP3K1_ST	Q8NHW3	MAFA	Q13233	MAP3K1	T53	S52L	52	Missense	proximal	-1	no	2.714	2.771	EPSD	ICGC;COSMIC	2.285	Up-regulation
STE_STE11_MEKK1_MAP3K1_ST	Q13158	FADD	Q13233	MAP3K1	S10	V11L	11	Missense	proximal	1	no	2.569	2.565	EPSD	ICGC	2.285	Down-regulation
STE_STE11_MEKK1_MAP3K1_ST	Q13158	FADD	Q13233	MAP3K1	S10	S14I	14	Missense	distal	4	no	2.569	2.960	EPSD	ICGC;COSMIC	2.285	Up-regulation
STE_STE11_MEKK1_MAP3K1_ST	Q13158	FADD	Q13233	MAP3K1	S14	V11L	11	Missense	distal	-3	no	3.006	2.769	EPSD	ICGC	2.285	Down-regulation
STE_STE11_MEKK1_MAP3K1_ST	Q13158	FADD	Q13233	MAP3K1	S14	S14I	14	Missense	central	0	yes	3.006	0.000	EPSD	ICGC;COSMIC	2.285	Loss
STE_STE11_MEKK1_MAP3K1_ST	Q13158	FADD	Q13233	MAP3K1	S16	V11L	11	Missense	distal	-5	no	2.805	3.136	EPSD	ICGC	2.285	Up-regulation
STE_STE11_MEKK1_MAP3K1_ST	Q13158	FADD	Q13233	MAP3K1	S16	S14I	14	Missense	proximal	-2	no	2.805	2.649	EPSD	ICGC;COSMIC	2.285	Down-regulation
STE_STE11_MEKK1_MAP3K1_ST	Q13158	FADD	Q13233	MAP3K1	S18	V11L	11	Missense	distal	-7	no	2.915	2.925	EPSD	ICGC	2.285	Up-regulation
STE_STE11_MEKK1_MAP3K1_ST	Q13158	FADD	Q13233	MAP3K1	S18	S14I	14	Missense	distal	-4	no	2.915	2.320	EPSD	ICGC;COSMIC	2.285	Down-regulation
STE_STE11_MEKK1_MAP3K1_ST	Q13158	FADD	Q13233	MAP3K1	S194	Q187H	187	Missense	distal	-7	no	3.865	3.874	PhosphoSitePlus	ICGC;COSMIC	2.285	Up-regulation
STE_STE11_MEKK1_MAP3K1_ST	Q13158	FADD	Q13233	MAP3K1	S194	S197T	197	Missense	distal	3	no	3.865	3.891	PhosphoSitePlus	ICGC	2.285	Up-regulation
STE_STE11_MEKK1_MAP3K1_ST	Q13158	FADD	Q13233	MAP3K1	S194	N199T	199	Missense	distal	5	no	3.865	3.852	PhosphoSitePlus	ICGC;COSMIC	2.285	Down-regulation
Other_Bud32_TP53RK_ST	P04637	TP53	Q96S44	TP53RK	S15	E11K	11	Missense	distal	-4	no	5.157	5.162	PhosphoSitePlus	ICGC;COSMIC	2.118	Up-regulation
Other_Bud32_TP53RK_ST	P04637	TP53	Q96S44	TP53RK	S46	D48G	48	Missense	proximal	2	no	2.106	2.130	EPSD	ICGC;COSMIC	2.118	Gain
Other_Bud32_TP53RK_ST	P04637	TP53	Q96S44	TP53RK	S46	Q52K	52	Missense	distal	6	no	2.106	2.155	EPSD	ICGC	2.118	Gain
Other_Bud32_TP53RK_ST	P04637	TP53	Q96S44	TP53RK	S215	P219T	219	Missense	distal	4	no	1.875	2.127	EPSD	ICGC;COSMIC	2.118	Gain
TK_ALK_ALK_Y	Q9UM73	ALK	Q9UM73	ALK	Y1278	R1275Q	1275	Missense	distal	-3	no	5.275	5.249	PhosphoSitePlus	ICGC;COSMIC;GDSC;CCLE	2.462	Down-regulation
TK_ALK_ALK_Y	Q9UM73	ALK	Q9UM73	ALK	Y1278	A1280E	1280	Missense	proximal	2	no	5.275	5.234	PhosphoSitePlus	ICGC	2.462	Down-regulation
TK_ALK_ALK_Y	Q9UM73	ALK	Q9UM73	ALK	Y1278	R1275L	1275	Missense	distal	-3	no	5.275	5.246	PhosphoSitePlus	ICGC;COSMIC	2.462	Down-regulation
TK_ALK_ALK_Y	Q9UM73	ALK	Q9UM73	ALK	Y1278	G1272E	1272	Missense	distal	-6	no	5.275	4.966	PhosphoSitePlus	ICGC;COSMIC	2.462	Down-regulation
TK_ALK_ALK_Y	Q9UM73	ALK	Q9UM73	ALK	Y1278	R1279M	1279	Missense	proximal	1	no	5.275	5.346	PhosphoSitePlus	ICGC;COSMIC	2.462	Up-regulation
TK_ALK_ALK_Y	Q9UM73	ALK	Q9UM73	ALK	Y1282	A1289V	1289	Missense	distal	7	no	5.394	5.343	EPSD	ICGC;COSMIC;GDSC;CCLE	2.462	Down-regulation
TK_ALK_ALK_Y	Q9UM73	ALK	Q9UM73	ALK	Y1282	R1275Q	1275	Missense	distal	-7	no	5.394	5.307	EPSD	ICGC;COSMIC;GDSC;CCLE	2.462	Down-regulation
TK_ALK_ALK_Y	Q9UM73	ALK	Q9UM73	ALK	Y1282	A1280E	1280	Missense	proximal	-2	no	5.394	5.441	EPSD	ICGC	2.462	Up-regulation
TK_ALK_ALK_Y	Q9UM73	ALK	Q9UM73	ALK	Y1282	R1275L	1275	Missense	distal	-7	no	5.394	5.263	EPSD	ICGC;COSMIC	2.462	Down-regulation
TK_ALK_ALK_Y	Q9UM73	ALK	Q9UM73	ALK	Y1282	R1279M	1279	Missense	distal	-3	no	5.394	5.371	EPSD	ICGC;COSMIC	2.462	Down-regulation
TK_ALK_ALK_Y	Q9UM73	ALK	Q9UM73	ALK	Y1283	A1289V	1289	Missense	distal	6	no	5.097	5.090	EPSD	ICGC;COSMIC;GDSC;CCLE	2.462	Down-regulation
TK_ALK_ALK_Y	Q9UM73	ALK	Q9UM73	ALK	Y1283	A1280E	1280	Missense	distal	-3	no	5.097	5.095	EPSD	ICGC	2.462	Down-regulation
TK_ALK_ALK_Y	Q9UM73	ALK	Q9UM73	ALK	Y1283	R1279M	1279	Missense	distal	-4	no	5.097	4.571	EPSD	ICGC;COSMIC	2.462	Down-regulation
TK_ALK_ALK_Y	P23246	SFPQ	Q9UM73	ALK	Y293	Q295K	295	Missense	proximal	2	no	5.156	5.191	PhosphoSitePlus	ICGC	2.462	Up-regulation
TK_ALK_ALK_Y	P23246	SFPQ	Q9UM73	ALK	Y293	T294K	294	Missense	proximal	1	no	5.156	5.178	PhosphoSitePlus	ICGC	2.462	Up-regulation
TK_ALK_ALK_Y	P23246	SFPQ	Q9UM73	ALK	Y293	R298W	298	Missense	distal	5	no	5.156	5.148	PhosphoSitePlus	ICGC	2.462	Down-regulation
TK_ALK_ALK_Y	P31939	ATIC	Q9UM73	ALK	Y104	N102S	102	Missense	proximal	-2	no	5.385	5.506	PhosphoSitePlus	ICGC;COSMIC	2.462	Up-regulation
TK_ALK_ALK_Y	P31939	ATIC	Q9UM73	ALK	Y104	V107L	107	Missense	distal	3	no	5.385	5.403	PhosphoSitePlus	ICGC	2.462	Up-regulation
TK_ALK_ALK_Y	P31939	ATIC	Q9UM73	ALK	Y104	P105H	105	Missense	proximal	1	no	5.385	5.370	PhosphoSitePlus	ICGC;COSMIC	2.462	Down-regulation
TK_ALK_ALK_Y	P50552	VASP	Q9UM73	ALK	Y39	H40N	40	Missense	proximal	1	no	5.116	5.099	PhosphoSitePlus	ICGC;COSMIC	2.462	Down-regulation
TK_ALK_ALK_Y	P40763	STAT3	Q9UM73	ALK	Y705	A702T	702	Missense	distal	-3	no	5.411	5.414	PhosphoSitePlus	ICGC;COSMIC	2.462	Up-regulation
TK_ALK_ALK_Y	Q06124	PTPN11	Q9UM73	ALK	Y62	I56F	56	Missense	distal	-6	no	1.737	2.486	EPSD	ICGC;COSMIC	2.462	Gain
TK_ALK_ALK_Y	P62993	GRB2	Q9UM73	ALK	Y160	A163D	163	Missense	distal	3	no	5.249	5.279	PhosphoSitePlus	ICGC;COSMIC	2.462	Up-regulation
AGC_RSK_MSK_RPS6KA5_ST	P16220	CREB1	O75582	RPS6KA5	S133	D140A	140	Missense	distal	7	no	3.674	3.644	PhosphoSitePlus	ICGC;COSMIC	1.456	Down-regulation
AGC_RSK_MSK_RPS6KA5_ST	O75582	RPS6KA5	O75582	RPS6KA5	S212	S212F	212	Missense	central	0	yes	2.933	0.000	EPSD;PhosphoSitePlus	ICGC	1.456	Loss
AGC_RSK_MSK_RPS6KA5_ST	O75582	RPS6KA5	O75582	RPS6KA5	S381	F384L	384	Missense	distal	3	no	1.719	1.720	EPSD;PhosphoSitePlus	ICGC	1.456	Up-regulation
AGC_RSK_MSK_RPS6KA5_ST	O75582	RPS6KA5	O75582	RPS6KA5	S381	P380L	380	Missense	proximal	-1	no	1.719	1.722	EPSD;PhosphoSitePlus	ICGC	1.456	Up-regulation
AGC_RSK_MSK_RPS6KA5_ST	P54253	ATXN1	O75582	RPS6KA5	S25	S26C	26	Missense	proximal	1	no	1.538	1.529	EPSD	ICGC;COSMIC	1.456	Down-regulation
AGC_RSK_MSK_RPS6KA5_ST	P54253	ATXN1	O75582	RPS6KA5	S25	A21T	21	Missense	distal	-4	no	1.538	1.642	EPSD	ICGC;COSMIC	1.456	Up-regulation
AGC_RSK_MSK_RPS6KA5_ST	P54253	ATXN1	O75582	RPS6KA5	S26	S26C	26	Missense	central	0	yes	2.709	0.000	EPSD	ICGC;COSMIC	1.456	Loss
AGC_RSK_MSK_RPS6KA5_ST	P54253	ATXN1	O75582	RPS6KA5	S26	A21T	21	Missense	distal	-5	no	2.709	2.690	EPSD	ICGC;COSMIC	1.456	Down-regulation
AGC_RSK_MSK_RPS6KA5_ST	P54253	ATXN1	O75582	RPS6KA5	S82	S88F	88	Missense	distal	6	no	1.492	1.499	EPSD	ICGC	1.456	Up-regulation
AGC_RSK_MSK_RPS6KA5_ST	P54253	ATXN1	O75582	RPS6KA5	S262	R259H	259	Missense	distal	-3	no	1.676	0.762	EPSD	ICGC;COSMIC	1.456	Loss
AGC_RSK_MSK_RPS6KA5_ST	P54253	ATXN1	O75582	RPS6KA5	S262	A265D	265	Missense	distal	3	no	1.676	1.642	EPSD	ICGC	1.456	Down-regulation
AGC_RSK_MSK_RPS6KA5_ST	P54253	ATXN1	O75582	RPS6KA5	S406	T409N	409	Missense	distal	3	no	2.009	2.018	EPSD	ICGC;COSMIC	1.456	Up-regulation
AGC_RSK_MSK_RPS6KA5_ST	P54253	ATXN1	O75582	RPS6KA5	S406	R403C	403	Missense	distal	-3	no	2.009	1.034	EPSD	ICGC;COSMIC	1.456	Loss
AGC_RSK_MSK_RPS6KA5_ST	P54253	ATXN1	O75582	RPS6KA5	S406	P407S	407	Missense	proximal	1	no	2.009	2.014	EPSD	ICGC	1.456	Up-regulation
AGC_RSK_MSK_RPS6KA5_ST	P54253	ATXN1	O75582	RPS6KA5	S406	H402Y	402	Missense	distal	-4	no	2.009	2.030	EPSD	ICGC;COSMIC;GDSC;CCLE	1.456	Up-regulation
AGC_RSK_MSK_RPS6KA5_ST	P54253	ATXN1	O75582	RPS6KA5	S408	T409N	409	Missense	proximal	1	no	1.720	1.717	EPSD	ICGC;COSMIC	1.456	Down-regulation
AGC_RSK_MSK_RPS6KA5_ST	P54253	ATXN1	O75582	RPS6KA5	S408	R403C	403	Missense	distal	-5	no	1.720	1.681	EPSD	ICGC;COSMIC	1.456	Down-regulation
AGC_RSK_MSK_RPS6KA5_ST	P54253	ATXN1	O75582	RPS6KA5	S408	P407S	407	Missense	proximal	-1	no	1.720	1.725	EPSD	ICGC	1.456	Up-regulation
AGC_RSK_MSK_RPS6KA5_ST	P54253	ATXN1	O75582	RPS6KA5	S408	H402Y	402	Missense	distal	-6	no	1.720	1.730	EPSD	ICGC;COSMIC;GDSC;CCLE	1.456	Up-regulation
AGC_RSK_MSK_RPS6KA5_ST	P54253	ATXN1	O75582	RPS6KA5	S677	P672S	672	Missense	distal	-5	no	1.577	1.585	EPSD	ICGC;COSMIC	1.456	Up-regulation
AGC_RSK_MSK_RPS6KA5_ST	P54253	ATXN1	O75582	RPS6KA5	S775	T769K	769	Missense	distal	-6	no	3.524	3.491	PhosphoSitePlus	ICGC	1.456	Down-regulation
AGC_RSK_MSK_RPS6KA5_ST	P54253	ATXN1	O75582	RPS6KA5	S775	R770K	770	Missense	distal	-5	no	3.524	3.495	PhosphoSitePlus	ICGC	1.456	Down-regulation
AGC_RSK_MSK_RPS6KA5_ST	P54253	ATXN1	O75582	RPS6KA5	S775	A776E	776	Missense	proximal	1	no	3.524	3.534	PhosphoSitePlus	ICGC	1.456	Up-regulation
AGC_RSK_MSK_RPS6KA5_ST	P18846	ATF1	O75582	RPS6KA5	S33	Q30K	30	Missense	distal	-3	no	1.336	1.511	EPSD	ICGC;COSMIC	1.456	Gain
AGC_RSK_MSK_RPS6KA5_ST	P18846	ATF1	O75582	RPS6KA5	S47	Q42K	42	Missense	distal	-5	no	1.541	1.547	EPSD	ICGC;COSMIC	1.456	Up-regulation
AGC_RSK_MSK_RPS6KA5_ST	P18846	ATF1	O75582	RPS6KA5	S47	S44A	44	Missense	distal	-3	no	1.541	1.735	EPSD	ICGC;COSMIC	1.456	Up-regulation
AGC_RSK_MSK_RPS6KA5_ST	P18846	ATF1	O75582	RPS6KA5	S63	L68V	68	Missense	distal	5	no	4.068	4.066	PhosphoSitePlus	ICGC;COSMIC	1.456	Down-regulation
AGC_RSK_MSK_RPS6KA5_ST	P18846	ATF1	O75582	RPS6KA5	S63	D70Y	70	Missense	distal	7	no	4.068	4.063	PhosphoSitePlus	ICGC;COSMIC	1.456	Down-regulation
AGC_RSK_MSK_RPS6KA5_ST	P18846	ATF1	O75582	RPS6KA5	S63	R61H	61	Missense	proximal	-2	no	4.068	2.490	PhosphoSitePlus	ICGC;COSMIC	1.456	Down-regulation
AGC_RSK_MSK_RPS6KA5_ST	P18846	ATF1	O75582	RPS6KA5	S63	Y64C	64	Missense	proximal	1	no	4.068	4.067	PhosphoSitePlus	ICGC;COSMIC	1.456	Down-regulation
AGC_RSK_MSK_RPS6KA5_ST	Q04206	RELA	O75582	RPS6KA5	S45	G48S	48	Missense	distal	3	no	1.469	1.447	EPSD	ICGC;COSMIC	1.456	Loss
AGC_RSK_MSK_RPS6KA5_ST	Q04206	RELA	O75582	RPS6KA5	S45	R41H	41	Missense	distal	-4	no	1.469	1.570	EPSD	ICGC;COSMIC	1.456	Up-regulation
AGC_RSK_MSK_RPS6KA5_ST	Q04206	RELA	O75582	RPS6KA5	S203	R198Q	198	Missense	distal	-5	no	2.479	2.443	EPSD	ICGC	1.456	Down-regulation
AGC_RSK_MSK_RPS6KA5_ST	Q04206	RELA	O75582	RPS6KA5	S203	S203Y	203	Missense	central	0	yes	2.479	0.000	EPSD	ICGC	1.456	Loss
AGC_RSK_MSK_RPS6KA5_ST	Q04206	RELA	O75582	RPS6KA5	S238	A235S	235	Missense	distal	-3	no	3.013	2.818	EPSD	ICGC;COSMIC	1.456	Down-regulation
AGC_RSK_MSK_RPS6KA5_ST	Q04206	RELA	O75582	RPS6KA5	S238	R236Q	236	Missense	proximal	-2	no	3.013	1.425	EPSD	ICGC;COSMIC	1.456	Loss
AGC_RSK_MSK_RPS6KA5_ST	Q04206	RELA	O75582	RPS6KA5	S238	E234V	234	Missense	distal	-4	no	3.013	3.034	EPSD	ICGC	1.456	Up-regulation
AGC_RSK_MSK_RPS6KA5_ST	Q04206	RELA	O75582	RPS6KA5	S276	D277E	277	Missense	proximal	1	no	4.060	4.059	PhosphoSitePlus	ICGC;COSMIC	1.456	Down-regulation
AGC_RSK_MSK_RPS6KA5_ST	Q04206	RELA	O75582	RPS6KA5	S281	D277E	277	Missense	distal	-4	no	2.260	2.250	EPSD	ICGC;COSMIC	1.456	Down-regulation
AGC_RSK_MSK_RPS6KA5_ST	Q04206	RELA	O75582	RPS6KA5	S316	P317H	317	Missense	proximal	1	no	1.662	1.655	EPSD	ICGC;COSMIC	1.456	Down-regulation
AGC_RSK_MSK_RPS6KA5_ST	Q04206	RELA	O75582	RPS6KA5	S316	S311G	311	Missense	distal	-5	no	1.662	1.656	EPSD	ICGC;COSMIC	1.456	Down-regulation
AGC_RSK_MSK_RPS6KA5_ST	Q04206	RELA	O75582	RPS6KA5	S316	G320R	320	Missense	distal	4	no	1.662	1.697	EPSD	ICGC	1.456	Up-regulation
AGC_RSK_MSK_RPS6KA5_ST	Q04206	RELA	O75582	RPS6KA5	S316	T322I	322	Missense	distal	6	no	1.662	1.658	EPSD	ICGC;COSMIC	1.456	Down-regulation
AGC_RSK_MSK_RPS6KA5_ST	Q9H4A3	WNK1	O75582	RPS6KA5	S10	T12A	12	Missense	proximal	2	no	1.441	1.480	EPSD	ICGC;COSMIC	1.456	Gain
AGC_RSK_MSK_RPS6KA5_ST	Q9H4A3	WNK1	O75582	RPS6KA5	S29	S34C	34	Missense	distal	5	no	1.542	1.535	EPSD	ICGC;COSMIC	1.456	Down-regulation
AGC_RSK_MSK_RPS6KA5_ST	Q9H4A3	WNK1	O75582	RPS6KA5	S29	P23L	23	Missense	distal	-6	no	1.542	1.535	EPSD	ICGC;COSMIC	1.456	Down-regulation
AGC_RSK_MSK_RPS6KA5_ST	Q9H4A3	WNK1	O75582	RPS6KA5	S29	K26N	26	Missense	distal	-3	no	1.542	1.251	EPSD	ICGC	1.456	Loss
AGC_RSK_MSK_RPS6KA5_ST	Q9H4A3	WNK1	O75582	RPS6KA5	S29	S29L	29	Missense	central	0	yes	1.542	0.000	EPSD	ICGC;COSMIC	1.456	Loss
AGC_RSK_MSK_RPS6KA5_ST	Q9H4A3	WNK1	O75582	RPS6KA5	S29	G36W	36	Missense	distal	7	no	1.542	1.538	EPSD	ICGC;COSMIC	1.456	Down-regulation
AGC_RSK_MSK_RPS6KA5_ST	Q9H4A3	WNK1	O75582	RPS6KA5	T60	R57H	57	Missense	distal	-3	no	2.066	1.152	PhosphoSitePlus	ICGC;COSMIC;GDSC;CCLE	1.456	Loss
AGC_RSK_MSK_RPS6KA5_ST	Q9H4A3	WNK1	O75582	RPS6KA5	T60	G67E	67	Missense	distal	7	no	2.066	2.069	PhosphoSitePlus	ICGC	1.456	Up-regulation
AGC_RSK_MSK_RPS6KA5_ST	Q9H4A3	WNK1	O75582	RPS6KA5	T60	E53D	53	Missense	distal	-7	no	2.066	2.069	PhosphoSitePlus	ICGC	1.456	Up-regulation
AGC_RSK_MSK_RPS6KA5_ST	Q9H4A3	WNK1	O75582	RPS6KA5	T60	R66S	66	Missense	distal	6	no	2.066	2.067	PhosphoSitePlus	ICGC;GDSC;CCLE	1.456	Up-regulation
AGC_RSK_MSK_RPS6KA5_ST	Q9H4A3	WNK1	O75582	RPS6KA5	T60	H59N	59	Missense	proximal	-1	no	2.066	2.062	PhosphoSitePlus	ICGC;COSMIC	1.456	Down-regulation
AGC_RSK_MSK_RPS6KA5_ST	Q9H4A3	WNK1	O75582	RPS6KA5	T60	R56C	56	Missense	distal	-4	no	2.066	2.181	PhosphoSitePlus	ICGC;COSMIC	1.456	Up-regulation
AGC_RSK_MSK_RPS6KA5_ST	Q9H4A3	WNK1	O75582	RPS6KA5	T60	R55G	55	Missense	distal	-5	no	2.066	2.025	PhosphoSitePlus	ICGC;COSMIC	1.456	Down-regulation
AGC_RSK_MSK_RPS6KA5_ST	Q9H4A3	WNK1	O75582	RPS6KA5	T60	T60I	60	Missense	central	0	yes	2.066	0.000	PhosphoSitePlus	ICGC;COSMIC	1.456	Loss
AGC_RSK_MSK_RPS6KA5_ST	Q9H4A3	WNK1	O75582	RPS6KA5	S183	P178L	178	Missense	distal	-5	no	1.825	1.828	EPSD	ICGC	1.456	Up-regulation
AGC_RSK_MSK_RPS6KA5_ST	Q9H4A3	WNK1	O75582	RPS6KA5	S183	P179S	179	Missense	distal	-4	no	1.825	1.785	EPSD	ICGC;COSMIC	1.456	Down-regulation
AGC_RSK_MSK_RPS6KA5_ST	Q9H4A3	WNK1	O75582	RPS6KA5	S185	P178L	178	Missense	distal	-7	no	2.067	2.059	EPSD	ICGC	1.456	Down-regulation
AGC_RSK_MSK_RPS6KA5_ST	Q9H4A3	WNK1	O75582	RPS6KA5	S185	P179S	179	Missense	distal	-6	no	2.067	2.074	EPSD	ICGC;COSMIC	1.456	Up-regulation
AGC_RSK_MSK_RPS6KA5_ST	Q9H4A3	WNK1	O75582	RPS6KA5	S469	R467K	467	Missense	proximal	-2	no	2.679	1.325	EPSD	ICGC;COSMIC	1.456	Loss
AGC_RSK_MSK_RPS6KA5_ST	Q9H4A3	WNK1	O75582	RPS6KA5	S1105	S1105R	1105	Missense	central	0	yes	2.890	0.000	EPSD	ICGC	1.456	Loss
AGC_RSK_MSK_RPS6KA5_ST	Q9H4A3	WNK1	O75582	RPS6KA5	S1108	S1105R	1105	Missense	distal	-3	no	0.994	1.864	EPSD	ICGC	1.456	Gain
AGC_RSK_MSK_RPS6KA5_ST	Q9H4A3	WNK1	O75582	RPS6KA5	S1110	S1105R	1105	Missense	distal	-5	no	2.208	2.243	EPSD	ICGC	1.456	Up-regulation
AGC_RSK_MSK_RPS6KA5_ST	Q9H4A3	WNK1	O75582	RPS6KA5	S1838	V1837F	1837	Missense	proximal	-1	no	1.567	1.574	EPSD	ICGC;COSMIC	1.456	Up-regulation
AGC_RSK_MSK_RPS6KA5_ST	P11831	SRF	O75582	RPS6KA5	S16	G19W	19	Missense	distal	3	no	2.719	2.706	EPSD	ICGC	1.456	Down-regulation
AGC_RSK_MSK_RPS6KA5_ST	P11831	SRF	O75582	RPS6KA5	S16	G15V	15	Missense	proximal	-1	no	2.719	2.713	EPSD	ICGC;COSMIC	1.456	Down-regulation
AGC_RSK_MSK_RPS6KA5_ST	P11831	SRF	O75582	RPS6KA5	S103	G108C	108	Missense	distal	5	no	2.165	2.164	PhosphoSitePlus	ICGC	1.456	Down-regulation
AGC_RSK_MSK_RPS6KA5_ST	P11831	SRF	O75582	RPS6KA5	S103	G97A	97	Missense	distal	-6	no	2.165	2.131	PhosphoSitePlus	ICGC	1.456	Down-regulation
AGC_RSK_MSK_RPS6KA5_ST	P11831	SRF	O75582	RPS6KA5	S103	E104D	104	Missense	proximal	1	no	2.165	2.166	PhosphoSitePlus	ICGC;COSMIC	1.456	Up-regulation
AGC_RSK_MSK_RPS6KA5_ST	P11831	SRF	O75582	RPS6KA5	S237	A238S	238	Missense	proximal	1	no	2.866	2.883	EPSD	ICGC	1.456	Up-regulation
AGC_RSK_MSK_RPS6KA5_ST	P11831	SRF	O75582	RPS6KA5	S311	P305Q	305	Missense	distal	-6	no	1.567	1.550	EPSD	ICGC;COSMIC	1.456	Down-regulation
AGC_RSK_MSK_RPS6KA5_ST	P11831	SRF	O75582	RPS6KA5	S435	S439Y	439	Missense	distal	4	no	1.457	1.447	EPSD	ICGC;COSMIC	1.456	Loss
AGC_RSK_MSK_RPS6KA5_ST	P11831	SRF	O75582	RPS6KA5	S435	S435Y	435	Missense	central	0	yes	1.457	0.000	EPSD	ICGC;COSMIC	1.456	Loss
AGC_RSK_MSK_RPS6KA5_ST	P19419	ELK1	O75582	RPS6KA5	S303	G299S	299	Missense	distal	-4	no	1.903	1.875	EPSD	ICGC;COSMIC	1.456	Down-regulation
AGC_RSK_MSK_RPS6KA5_ST	P19419	ELK1	O75582	RPS6KA5	S303	A297G	297	Missense	distal	-6	no	1.903	1.937	EPSD	ICGC	1.456	Up-regulation
AGC_RSK_MSK_RPS6KA5_ST	P19419	ELK1	O75582	RPS6KA5	S304	G299S	299	Missense	distal	-5	no	1.739	1.745	EPSD	ICGC;COSMIC	1.456	Up-regulation
AGC_RSK_MSK_RPS6KA5_ST	P19419	ELK1	O75582	RPS6KA5	S304	A297G	297	Missense	distal	-7	no	1.739	1.765	EPSD	ICGC	1.456	Up-regulation
AGC_RSK_MSK_RPS6KA5_ST	P19419	ELK1	O75582	RPS6KA5	S383	S380R	380	Missense	distal	-3	no	1.211	2.081	PhosphoSitePlus	ICGC	1.456	Gain
AGC_RSK_MSK_RPS6KA5_ST	P07101	TH	O75582	RPS6KA5	S19	E20Q	20	Missense	proximal	1	no	2.445	2.442	EPSD	ICGC;COSMIC	1.456	Down-regulation
AGC_RSK_MSK_RPS6KA5_ST	P07101	TH	O75582	RPS6KA5	S19	K12R	12	Missense	distal	-7	no	2.445	2.394	EPSD	ICGC;COSMIC	1.456	Down-regulation
TK_EGFR_EGFR_Y	P52735	VAV2	P00533	EGFR	Y142	D140G	140	Missense	proximal	-2	no	11.200	7.962	PhosphoSitePlus;EPSD	ICGC;GDSC;CCLE	6.466	Down-regulation
TK_EGFR_EGFR_Y	P52735	VAV2	P00533	EGFR	Y142	R143H	143	Missense	proximal	1	no	11.200	12.535	PhosphoSitePlus;EPSD	ICGC;GDSC;CCLE	6.466	Up-regulation
TK_EGFR_EGFR_Y	P52735	VAV2	P00533	EGFR	Y159	V162I	162	Missense	distal	3	no	15.767	15.599	EPSD;PhosphoSitePlus	ICGC;COSMIC;GDSC	6.466	Down-regulation
TK_EGFR_EGFR_Y	P52735	VAV2	P00533	EGFR	Y172	D170E	170	Missense	proximal	-2	no	12.223	12.488	EPSD;PhosphoSitePlus	ICGC;COSMIC	6.466	Up-regulation
TK_EGFR_EGFR_Y	P52735	VAV2	P00533	EGFR	Y172	D170G	170	Missense	proximal	-2	no	12.223	8.985	EPSD;PhosphoSitePlus	ICGC;COSMIC	6.466	Down-regulation
TK_EGFR_EGFR_Y	P52735	VAV2	P00533	EGFR	Y172	G168R	168	Missense	distal	-4	no	12.223	10.531	EPSD;PhosphoSitePlus	ICGC;COSMIC	6.466	Down-regulation
TK_EGFR_EGFR_Y	Q8NFJ5	GPRC5A	P00533	EGFR	Y317	P319H	319	Missense	proximal	2	no	9.261	8.999	EPSD;PhosphoSitePlus	ICGC;COSMIC	6.466	Down-regulation
TK_EGFR_EGFR_Y	Q8NFJ5	GPRC5A	P00533	EGFR	Y320	P319H	319	Missense	proximal	-1	no	8.152	8.070	PhosphoSitePlus;EPSD	ICGC;COSMIC	6.466	Down-regulation
TK_EGFR_EGFR_Y	Q8IVM0	CCDC50	P00533	EGFR	Y145	R138L	138	Missense	distal	-7	no	6.831	6.180	EPSD	ICGC;COSMIC	6.466	Loss
TK_EGFR_EGFR_Y	P00533	EGFR	P00533	EGFR	Y869	L862M	862	Missense	distal	-7	no	12.957	13.251	EPSD;PhosphoSitePlus	ICGC;COSMIC	6.466	Up-regulation
TK_EGFR_EGFR_Y	P00533	EGFR	P00533	EGFR	Y998	S991R	991	Missense	distal	-7	no	7.773	8.098	EPSD	ICGC;COSMIC	6.466	Up-regulation
TK_EGFR_EGFR_Y	P00533	EGFR	P00533	EGFR	Y1110	G1103V	1103	Missense	distal	-7	no	11.780	11.041	EPSD;PhosphoSitePlus	ICGC	6.466	Down-regulation
TK_EGFR_EGFR_Y	P00533	EGFR	P00533	EGFR	Y1110	P1108L	1108	Missense	proximal	-2	no	11.780	6.358	EPSD;PhosphoSitePlus	ICGC;COSMIC	6.466	Loss
TK_EGFR_EGFR_Y	P00533	EGFR	P00533	EGFR	Y1125	A1118V	1118	Missense	distal	-7	no	11.851	10.730	EPSD	ICGC;COSMIC	6.466	Down-regulation
TK_EGFR_EGFR_Y	P00533	EGFR	P00533	EGFR	Y1138	P1136H	1136	Missense	proximal	-2	no	10.965	8.739	EPSD	ICGC	6.466	Down-regulation
TK_EGFR_EGFR_Y	P00533	EGFR	P00533	EGFR	Y1172	D1168N	1168	Missense	distal	-4	no	9.835	10.927	EPSD;PhosphoSitePlus	ICGC;COSMIC	6.466	Up-regulation
TK_EGFR_EGFR_Y	P00533	EGFR	P00533	EGFR	Y1172	N1169S	1169	Missense	distal	-3	no	9.835	8.914	EPSD;PhosphoSitePlus	ICGC	6.466	Down-regulation
TK_EGFR_EGFR_Y	P35222	CTNNB1	P00533	EGFR	Y716	R710H	710	Missense	distal	-6	no	7.581	7.604	EPSD	ICGC;COSMIC	6.466	Up-regulation
TK_EGFR_EGFR_Y	P19174	PLCG1	P00533	EGFR	Y210	G206E	206	Missense	distal	-4	no	5.353	6.796	EPSD	ICGC	6.466	Gain
TK_EGFR_EGFR_Y	P19174	PLCG1	P00533	EGFR	Y472	K465N	465	Missense	distal	-7	no	10.012	10.065	EPSD	ICGC	6.466	Up-regulation
TK_EGFR_EGFR_Y	P19174	PLCG1	P00533	EGFR	Y496	H503N	503	Missense	distal	7	no	6.447	6.916	EPSD	ICGC	6.466	Gain
TK_EGFR_EGFR_Y	P19174	PLCG1	P00533	EGFR	Y506	H503N	503	Missense	distal	-3	no	6.186	6.966	EPSD	ICGC	6.466	Gain
TK_EGFR_EGFR_Y	P19174	PLCG1	P00533	EGFR	Y702	R707Q	707	Missense	distal	5	no	7.167	7.352	EPSD	ICGC;COSMIC	6.466	Up-regulation
TK_EGFR_EGFR_Y	P19174	PLCG1	P00533	EGFR	Y702	A703V	703	Missense	proximal	1	no	7.167	7.734	EPSD	ICGC;COSMIC	6.466	Up-regulation
TK_EGFR_EGFR_Y	P19174	PLCG1	P00533	EGFR	Y771	R778H	778	Missense	distal	7	no	10.925	10.625	PhosphoSitePlus;EPSD	ICGC;COSMIC	6.466	Down-regulation
TK_EGFR_EGFR_Y	P19174	PLCG1	P00533	EGFR	Y771	G772E	772	Missense	proximal	1	no	10.925	10.829	PhosphoSitePlus;EPSD	ICGC	6.466	Down-regulation
TK_EGFR_EGFR_Y	P19174	PLCG1	P00533	EGFR	Y771	A767V	767	Missense	distal	-4	no	10.925	10.560	PhosphoSitePlus;EPSD	ICGC;COSMIC	6.466	Down-regulation
TK_EGFR_EGFR_Y	P19174	PLCG1	P00533	EGFR	Y783	R778H	778	Missense	distal	-5	no	8.649	8.990	EPSD;PhosphoSitePlus	ICGC;COSMIC	6.466	Up-regulation
TK_EGFR_EGFR_Y	P19174	PLCG1	P00533	EGFR	Y1196	S1197N	1197	Missense	proximal	1	no	5.723	6.612	EPSD	ICGC;COSMIC	6.466	Gain
TK_EGFR_EGFR_Y	P19174	PLCG1	P00533	EGFR	Y1253	R1252H	1252	Missense	proximal	-1	no	11.096	11.317	EPSD	ICGC;COSMIC;CCLE	6.466	Up-regulation
TK_EGFR_EGFR_Y	P19174	PLCG1	P00533	EGFR	Y1253	Q1255K	1255	Missense	proximal	2	no	11.096	10.202	EPSD	ICGC;COSMIC	6.466	Down-regulation
TK_EGFR_EGFR_Y	Q05397	PTK2	P00533	EGFR	Y194	A187T	187	Missense	distal	-7	no	15.865	15.766	EPSD;PhosphoSitePlus	ICGC;COSMIC	6.466	Down-regulation
TK_EGFR_EGFR_Y	Q05397	PTK2	P00533	EGFR	Y898	S897Y	897	Missense	proximal	-1	no	6.638	5.312	EPSD	ICGC	6.466	Loss
TK_EGFR_EGFR_Y	Q05397	PTK2	P00533	EGFR	Y898	S897N	897	Missense	proximal	-1	no	6.638	7.367	EPSD	ICGC;COSMIC	6.466	Up-regulation
TK_EGFR_EGFR_Y	Q05397	PTK2	P00533	EGFR	Y898	S897C	897	Missense	proximal	-1	no	6.638	5.671	EPSD	ICGC	6.466	Loss
TK_EGFR_EGFR_Y	P12004	PCNA	P00533	EGFR	Y211	T206A	206	Missense	distal	-5	no	7.900	7.959	PhosphoSitePlus	ICGC;COSMIC	6.466	Up-regulation
TK_EGFR_EGFR_Y	P12004	PCNA	P00533	EGFR	Y211	F214V	214	Missense	distal	3	no	7.900	8.435	PhosphoSitePlus	ICGC	6.466	Up-regulation
TK_EGFR_EGFR_Y	P12004	PCNA	P00533	EGFR	Y211	R210K	210	Missense	proximal	-1	no	7.900	6.784	PhosphoSitePlus	ICGC;COSMIC	6.466	Down-regulation
TK_EGFR_EGFR_Y	Q13480	GAB1	P00533	EGFR	Y285	G292W	292	Missense	distal	7	no	10.197	9.820	EPSD;PhosphoSitePlus	ICGC;COSMIC	6.466	Down-regulation
TK_EGFR_EGFR_Y	Q13480	GAB1	P00533	EGFR	Y307	P311L	311	Missense	distal	4	no	7.462	7.606	EPSD	ICGC	6.466	Up-regulation
TK_EGFR_EGFR_Y	Q13480	GAB1	P00533	EGFR	Y307	M300L	300	Missense	distal	-7	no	7.462	7.167	EPSD	ICGC;COSMIC	6.466	Down-regulation
TK_EGFR_EGFR_Y	Q13480	GAB1	P00533	EGFR	Y373	G379W	379	Missense	distal	6	no	9.862	9.707	EPSD;PhosphoSitePlus	ICGC;COSMIC	6.466	Down-regulation
TK_EGFR_EGFR_Y	Q13480	GAB1	P00533	EGFR	Y373	P376T	376	Missense	distal	3	no	9.862	10.013	EPSD;PhosphoSitePlus	ICGC;COSMIC	6.466	Up-regulation
TK_EGFR_EGFR_Y	Q13480	GAB1	P00533	EGFR	Y406	A400V	400	Missense	distal	-6	no	12.131	12.082	PhosphoSitePlus;EPSD	ICGC	6.466	Down-regulation
TK_EGFR_EGFR_Y	Q13480	GAB1	P00533	EGFR	Y447	V448I	448	Missense	proximal	1	no	12.802	11.138	EPSD;PhosphoSitePlus	ICGC;COSMIC	6.466	Down-regulation
TK_EGFR_EGFR_Y	Q13480	GAB1	P00533	EGFR	Y447	D444Y	444	Missense	distal	-3	no	12.802	10.788	EPSD;PhosphoSitePlus	ICGC	6.466	Down-regulation
TK_EGFR_EGFR_Y	Q13480	GAB1	P00533	EGFR	Y447	M450I	450	Missense	distal	3	no	12.802	13.177	EPSD;PhosphoSitePlus	ICGC	6.466	Up-regulation
TK_EGFR_EGFR_Y	Q13480	GAB1	P00533	EGFR	Y472	G478R	478	Missense	distal	6	no	14.196	14.027	EPSD;PhosphoSitePlus	ICGC	6.466	Down-regulation
TK_EGFR_EGFR_Y	Q13480	GAB1	P00533	EGFR	Y472	M475I	475	Missense	distal	3	no	14.196	14.571	EPSD;PhosphoSitePlus	ICGC	6.466	Up-regulation
TK_EGFR_EGFR_Y	Q14457	BECN1	P00533	EGFR	Y229	Q230H	230	Missense	proximal	1	no	10.632	10.144	EPSD;PhosphoSitePlus	ICGC;COSMIC	6.466	Down-regulation
TK_EGFR_EGFR_Y	Q14457	BECN1	P00533	EGFR	Y233	Q240K	240	Missense	distal	7	no	7.122	7.152	PhosphoSitePlus;EPSD	ICGC	6.466	Up-regulation
TK_EGFR_EGFR_Y	Q14457	BECN1	P00533	EGFR	Y233	Q230H	230	Missense	distal	-3	no	7.122	6.872	PhosphoSitePlus;EPSD	ICGC;COSMIC	6.466	Down-regulation
TK_EGFR_EGFR_Y	O14939	PLD2	P00533	EGFR	Y169	Y169C	169	Missense	central	0	yes	8.543	0.000	EPSD	ICGC	6.466	Loss
TK_EGFR_EGFR_Y	O14939	PLD2	P00533	EGFR	Y169	R172C	172	Missense	distal	3	no	8.543	9.077	EPSD	ICGC;COSMIC	6.466	Up-regulation
TK_EGFR_EGFR_Y	O14939	PLD2	P00533	EGFR	Y179	R180H	180	Missense	proximal	1	no	6.029	7.365	EPSD	ICGC	6.466	Gain
TK_EGFR_EGFR_Y	O14939	PLD2	P00533	EGFR	Y296	K292E	292	Missense	distal	-4	no	8.334	10.447	PhosphoSitePlus	ICGC	6.466	Up-regulation
TK_EGFR_EGFR_Y	O14939	PLD2	P00533	EGFR	Y296	A299S	299	Missense	distal	3	no	8.334	8.309	PhosphoSitePlus	ICGC;COSMIC	6.466	Down-regulation
TK_EGFR_EGFR_Y	P40818	USP8	P00533	EGFR	Y717	P720R	720	Missense	distal	3	no	9.285	9.005	PhosphoSitePlus;EPSD	ICGC;COSMIC	6.466	Down-regulation
TK_EGFR_EGFR_Y	P40818	USP8	P00533	EGFR	Y717	I722K	722	Missense	distal	5	no	9.285	9.381	PhosphoSitePlus;EPSD	ICGC;COSMIC	6.466	Up-regulation
TK_EGFR_EGFR_Y	P40818	USP8	P00533	EGFR	Y810	F805L	805	Missense	distal	-5	no	10.647	10.946	EPSD;PhosphoSitePlus	ICGC;COSMIC	6.466	Up-regulation
TK_EGFR_EGFR_Y	P40818	USP8	P00533	EGFR	Y810	R807Q	807	Missense	distal	-3	no	10.647	11.315	EPSD;PhosphoSitePlus	ICGC;COSMIC	6.466	Up-regulation
TK_EGFR_EGFR_Y	P40818	USP8	P00533	EGFR	Y810	R807L	807	Missense	distal	-3	no	10.647	8.645	EPSD;PhosphoSitePlus	ICGC	6.466	Down-regulation
TK_EGFR_EGFR_Y	O00767	SCD	P00533	EGFR	Y59	E63K	63	Missense	distal	4	no	8.552	9.263	EPSD	ICGC;COSMIC	6.466	Up-regulation
TK_EGFR_EGFR_Y	P11171	EPB41	P00533	EGFR	Y660	R653H	653	Missense	distal	-7	no	11.750	11.368	EPSD	ICGC;COSMIC	6.466	Down-regulation
TK_EGFR_EGFR_Y	P11171	EPB41	P00533	EGFR	Y660	R653C	653	Missense	distal	-7	no	11.750	11.115	EPSD	ICGC;COSMIC	6.466	Down-regulation
TK_EGFR_EGFR_Y	Q38SD2	LRRK1	P00533	EGFR	Y971	Q970K	970	Missense	proximal	-1	no	11.746	11.730	PhosphoSitePlus	ICGC	6.466	Down-regulation
TK_EGFR_EGFR_Y	Q13315	ATM	P00533	EGFR	Y370	L364F	364	Missense	distal	-6	no	7.915	7.926	PhosphoSitePlus	ICGC;COSMIC	6.466	Up-regulation
TK_EGFR_EGFR_Y	Q13315	ATM	P00533	EGFR	Y370	S367F	367	Missense	distal	-3	no	7.915	6.920	PhosphoSitePlus	ICGC;COSMIC	6.466	Down-regulation
TK_EGFR_EGFR_Y	Q13315	ATM	P00533	EGFR	Y380	S378R	378	Missense	proximal	-2	no	6.903	4.271	EPSD	ICGC;COSMIC	6.466	Loss
TK_EGFR_EGFR_Y	Q13315	ATM	P00533	EGFR	Y380	K385R	385	Missense	distal	5	no	6.903	6.792	EPSD	ICGC;COSMIC	6.466	Down-regulation
TK_EGFR_EGFR_Y	Q13315	ATM	P00533	EGFR	Y380	K385E	385	Missense	distal	5	no	6.903	6.915	EPSD	ICGC;COSMIC	6.466	Up-regulation
TK_EGFR_EGFR_Y	Q13315	ATM	P00533	EGFR	Y380	K387N	387	Missense	distal	7	no	6.903	7.058	EPSD	ICGC;COSMIC	6.466	Up-regulation
TK_EGFR_EGFR_Y	Q13315	ATM	P00533	EGFR	Y380	R386M	386	Missense	distal	6	no	6.903	7.479	EPSD	ICGC;COSMIC	6.466	Up-regulation
TK_EGFR_EGFR_Y	Q13315	ATM	P00533	EGFR	Y2969	A2967S	2967	Missense	proximal	-2	no	9.042	10.182	EPSD	ICGC	6.466	Up-regulation
TK_EGFR_EGFR_Y	Q9P0J1	PDP1	P00533	EGFR	Y381	P386S	386	Missense	distal	5	no	10.792	11.019	PhosphoSitePlus	ICGC	6.466	Up-regulation
TK_EGFR_EGFR_Y	Q9P0J1	PDP1	P00533	EGFR	Y381	N377H	377	Missense	distal	-4	no	10.792	8.227	PhosphoSitePlus	ICGC;COSMIC	6.466	Down-regulation
TK_EGFR_EGFR_Y	O95477	ABCA1	P00533	EGFR	Y325	S321C	321	Missense	distal	-4	no	9.459	9.291	EPSD	ICGC	6.466	Down-regulation
TK_EGFR_EGFR_Y	O95477	ABCA1	P00533	EGFR	Y325	A332D	332	Missense	distal	7	no	9.459	9.307	EPSD	ICGC	6.466	Down-regulation
TK_EGFR_EGFR_Y	O95477	ABCA1	P00533	EGFR	Y325	E326V	326	Missense	proximal	1	no	9.459	10.613	EPSD	ICGC;COSMIC	6.466	Up-regulation
TK_EGFR_EGFR_Y	O15492	RGS16	P00533	EGFR	Y168	R170C	170	Missense	proximal	2	no	10.754	10.551	PhosphoSitePlus	ICGC;COSMIC;CCLE	6.466	Down-regulation
TK_EGFR_EGFR_Y	O15492	RGS16	P00533	EGFR	Y168	E164K	164	Missense	distal	-4	no	10.754	8.642	PhosphoSitePlus	ICGC	6.466	Down-regulation
TK_EGFR_EGFR_Y	O15492	RGS16	P00533	EGFR	Y177	R170C	170	Missense	distal	-7	no	7.375	6.741	EPSD	ICGC;COSMIC;CCLE	6.466	Down-regulation
TK_EGFR_EGFR_Y	O15492	RGS16	P00533	EGFR	Y177	R178Q	178	Missense	proximal	1	no	7.375	9.199	EPSD	ICGC;COSMIC	6.466	Up-regulation
TK_EGFR_EGFR_Y	O15492	RGS16	P00533	EGFR	Y177	D179E	179	Missense	proximal	2	no	7.375	7.453	EPSD	ICGC	6.466	Up-regulation
TK_EGFR_EGFR_Y	Q9P219	CCDC88C	P00533	EGFR	Y219	R217W	217	Missense	proximal	-2	no	11.339	4.465	EPSD	ICGC	6.466	Loss
TK_EGFR_EGFR_Y	Q9P219	CCDC88C	P00533	EGFR	Y219	Q221H	221	Missense	proximal	2	no	11.339	10.655	EPSD	ICGC;COSMIC	6.466	Down-regulation
TK_EGFR_EGFR_Y	Q9P219	CCDC88C	P00533	EGFR	Y219	R217L	217	Missense	proximal	-2	no	11.339	8.287	EPSD	ICGC;COSMIC	6.466	Down-regulation
TK_EGFR_EGFR_Y	P18031	PTPN1	P00533	EGFR	Y46	R45S	45	Missense	proximal	-1	no	7.735	7.990	EPSD	ICGC	6.466	Up-regulation
TK_EGFR_EGFR_Y	P18031	PTPN1	P00533	EGFR	Y66	A69T	69	Missense	distal	3	no	12.851	12.608	PhosphoSitePlus	ICGC	6.466	Down-regulation
TK_EGFR_EGFR_Y	P15311	EZR	P00533	EGFR	Y116	P118T	118	Missense	proximal	2	no	10.057	9.421	EPSD	ICGC	6.466	Down-regulation
TK_EGFR_EGFR_Y	P15311	EZR	P00533	EGFR	Y116	I110T	110	Missense	distal	-6	no	10.057	10.062	EPSD	ICGC	6.466	Up-regulation
TK_EGFR_EGFR_Y	P15311	EZR	P00533	EGFR	Y146	H142Q	142	Missense	distal	-4	no	8.664	9.997	EPSD;PhosphoSitePlus	ICGC;COSMIC	6.466	Up-regulation
TK_EGFR_EGFR_Y	P15311	EZR	P00533	EGFR	Y146	H142N	142	Missense	distal	-4	no	8.664	11.230	EPSD;PhosphoSitePlus	ICGC;COSMIC	6.466	Up-regulation
TK_EGFR_EGFR_Y	P15311	EZR	P00533	EGFR	Y205	F206L	206	Missense	proximal	1	no	7.639	7.086	EPSD	ICGC	6.466	Down-regulation
TK_EGFR_EGFR_Y	P15311	EZR	P00533	EGFR	Y354	K357T	357	Missense	distal	3	no	8.003	8.726	PhosphoSitePlus;EPSD	ICGC;COSMIC	6.466	Up-regulation
TK_EGFR_EGFR_Y	P15311	EZR	P00533	EGFR	Y354	A361E	361	Missense	distal	7	no	8.003	7.995	PhosphoSitePlus;EPSD	ICGC	6.466	Down-regulation
TK_EGFR_EGFR_Y	P15311	EZR	P00533	EGFR	Y424	L421I	421	Missense	distal	-3	no	8.292	8.389	EPSD	ICGC	6.466	Up-regulation
TK_EGFR_EGFR_Y	P15311	EZR	P00533	EGFR	Y424	A418D	418	Missense	distal	-6	no	8.292	8.253	EPSD	ICGC	6.466	Down-regulation
TK_EGFR_EGFR_Y	P15311	EZR	P00533	EGFR	Y499	A494T	494	Missense	distal	-5	no	12.598	12.540	EPSD	ICGC;COSMIC	6.466	Down-regulation
TK_EGFR_EGFR_Y	P15311	EZR	P00533	EGFR	Y499	S504C	504	Missense	distal	5	no	12.598	12.527	EPSD	ICGC;COSMIC	6.466	Down-regulation
TK_EGFR_EGFR_Y	Q92529	SHC3	P00533	EGFR	Y341	N343K	343	Missense	proximal	2	no	8.084	6.077	EPSD	ICGC	6.466	Loss
TK_EGFR_EGFR_Y	Q92529	SHC3	P00533	EGFR	Y341	S344R	344	Missense	distal	3	no	8.084	7.437	EPSD	ICGC	6.466	Down-regulation
TK_EGFR_EGFR_Y	Q92529	SHC3	P00533	EGFR	Y341	H339L	339	Missense	proximal	-2	no	8.084	4.889	EPSD	ICGC;COSMIC	6.466	Loss
TK_EGFR_EGFR_Y	Q92529	SHC3	P00533	EGFR	Y342	N343K	343	Missense	proximal	1	no	9.915	9.288	EPSD	ICGC	6.466	Down-regulation
TK_EGFR_EGFR_Y	Q92529	SHC3	P00533	EGFR	Y342	S344R	344	Missense	proximal	2	no	9.915	8.441	EPSD	ICGC	6.466	Down-regulation
TK_EGFR_EGFR_Y	Q92529	SHC3	P00533	EGFR	Y342	H339L	339	Missense	distal	-3	no	9.915	7.495	EPSD	ICGC;COSMIC	6.466	Down-regulation
TK_EGFR_EGFR_Y	Q92529	SHC3	P00533	EGFR	Y379	G374R	374	Missense	distal	-5	no	12.223	12.512	EPSD	ICGC;COSMIC	6.466	Up-regulation
TK_EGFR_EGFR_Y	Q92529	SHC3	P00533	EGFR	Y379	Q381K	381	Missense	proximal	2	no	12.223	11.329	EPSD	ICGC	6.466	Down-regulation
TK_EGFR_EGFR_Y	Q92529	SHC3	P00533	EGFR	Y379	G374E	374	Missense	distal	-5	no	12.223	13.520	EPSD	ICGC;COSMIC	6.466	Up-regulation
TK_EGFR_EGFR_Y	Q92529	SHC3	P00533	EGFR	Y380	G374R	374	Missense	distal	-6	no	8.585	8.613	EPSD	ICGC;COSMIC	6.466	Up-regulation
TK_EGFR_EGFR_Y	Q92529	SHC3	P00533	EGFR	Y380	Q381K	381	Missense	proximal	1	no	8.585	7.584	EPSD	ICGC	6.466	Down-regulation
TK_EGFR_EGFR_Y	Q92529	SHC3	P00533	EGFR	Y380	G374E	374	Missense	distal	-6	no	8.585	8.691	EPSD	ICGC;COSMIC	6.466	Up-regulation
TK_EGFR_EGFR_Y	Q92529	SHC3	P00533	EGFR	Y380	D387Y	387	Missense	distal	7	no	8.585	8.529	EPSD	ICGC	6.466	Down-regulation
TK_EGFR_EGFR_Y	Q92529	SHC3	P00533	EGFR	Y406	S407T	407	Missense	proximal	1	no	12.044	12.417	EPSD	ICGC;COSMIC	6.466	Up-regulation
TK_EGFR_EGFR_Y	Q92529	SHC3	P00533	EGFR	Y406	P409Q	409	Missense	distal	3	no	12.044	12.286	EPSD	ICGC	6.466	Up-regulation
TK_EGFR_EGFR_Y	Q92529	SHC3	P00533	EGFR	Y406	T408K	408	Missense	proximal	2	no	12.044	12.209	EPSD	ICGC	6.466	Up-regulation
TK_EGFR_EGFR_Y	Q92529	SHC3	P00533	EGFR	Y424	P431L	431	Missense	distal	7	no	11.166	10.875	EPSD	ICGC;COSMIC	6.466	Down-regulation
TK_EGFR_EGFR_Y	Q92529	SHC3	P00533	EGFR	Y424	Q428K	428	Missense	distal	4	no	11.166	11.631	EPSD	ICGC	6.466	Up-regulation
TK_EGFR_EGFR_Y	Q92529	SHC3	P00533	EGFR	Y424	T418K	418	Missense	distal	-6	no	11.166	11.186	EPSD	ICGC	6.466	Up-regulation
TK_EGFR_EGFR_Y	Q92529	SHC3	P00533	EGFR	Y424	V425I	425	Missense	proximal	1	no	11.166	9.502	EPSD	ICGC;COSMIC	6.466	Down-regulation
TK_EGFR_EGFR_Y	P07948	LYN	P00533	EGFR	Y32	S38A	38	Missense	distal	6	no	9.229	9.366	PhosphoSitePlus	ICGC	6.466	Up-regulation
TK_EGFR_EGFR_Y	P07948	LYN	P00533	EGFR	Y32	V33L	33	Missense	proximal	1	no	9.229	8.673	PhosphoSitePlus	ICGC	6.466	Down-regulation
TK_EGFR_EGFR_Y	P07948	LYN	P00533	EGFR	Y32	T37A	37	Missense	distal	5	no	9.229	9.340	PhosphoSitePlus	ICGC;COSMIC	6.466	Up-regulation
TK_EGFR_EGFR_Y	P07948	LYN	P00533	EGFR	Y32	V33M	33	Missense	proximal	1	no	9.229	8.006	PhosphoSitePlus	ICGC;COSMIC	6.466	Down-regulation
TK_EGFR_EGFR_Y	P07948	LYN	P00533	EGFR	Y117	E110K	110	Missense	distal	-7	no	7.078	6.477	EPSD	ICGC	6.466	Down-regulation
TK_EGFR_EGFR_Y	P07948	LYN	P00533	EGFR	Y117	A119S	119	Missense	proximal	2	no	7.078	7.261	EPSD	ICGC	6.466	Up-regulation
TK_EGFR_EGFR_Y	P07948	LYN	P00533	EGFR	Y117	K120R	120	Missense	distal	3	no	7.078	7.370	EPSD	ICGC	6.466	Up-regulation
TK_EGFR_EGFR_Y	P07948	LYN	P00533	EGFR	Y316	A323T	323	Missense	distal	7	no	7.732	7.645	EPSD	ICGC;COSMIC	6.466	Down-regulation
TK_EGFR_EGFR_Y	P07948	LYN	P00533	EGFR	Y397	T398K	398	Missense	proximal	1	no	8.824	8.713	EPSD	ICGC;COSMIC	6.466	Down-regulation
TK_EGFR_EGFR_Y	P07948	LYN	P00533	EGFR	Y397	R400M	400	Missense	distal	3	no	8.824	9.096	EPSD	ICGC;COSMIC	6.466	Up-regulation
TK_EGFR_EGFR_Y	P48050	KCNJ4	P00533	EGFR	Y234	R240W	240	Missense	distal	6	no	8.609	8.623	PhosphoSitePlus	ICGC;COSMIC	6.466	Up-regulation
TK_EGFR_EGFR_Y	P48050	KCNJ4	P00533	EGFR	Y234	M228I	228	Missense	distal	-6	no	8.609	8.605	PhosphoSitePlus	ICGC;COSMIC	6.466	Down-regulation
TK_EGFR_EGFR_Y	P48050	KCNJ4	P00533	EGFR	Y234	R240Q	240	Missense	distal	6	no	8.609	8.816	PhosphoSitePlus	ICGC;COSMIC	6.466	Up-regulation
TK_EGFR_EGFR_Y	P48050	KCNJ4	P00533	EGFR	Y234	R240L	240	Missense	distal	6	no	8.609	8.247	PhosphoSitePlus	ICGC;COSMIC	6.466	Down-regulation
TK_EGFR_EGFR_Y	P14618	PKM	P00533	EGFR	Y148	C152Y	152	Missense	distal	4	no	10.187	10.399	PhosphoSitePlus	ICGC;COSMIC	6.466	Up-regulation
TK_EGFR_EGFR_Y	P14618	PKM	P00533	EGFR	Y148	D153E	153	Missense	distal	5	no	10.187	10.204	PhosphoSitePlus	ICGC	6.466	Up-regulation
TK_EGFR_EGFR_Y	P14618	PKM	P00533	EGFR	Y175	V170G	170	Missense	distal	-5	no	7.028	7.132	EPSD	ICGC	6.466	Up-regulation
TK_EGFR_EGFR_Y	Q8TDY4	ASAP3	P00533	EGFR	Y34	R35Q	35	Missense	proximal	1	no	8.816	10.640	PhosphoSitePlus	ICGC	6.466	Up-regulation
TK_EGFR_EGFR_Y	Q14164	IKBKE	P00533	EGFR	Y153	D157Y	157	Missense	distal	4	no	13.253	13.921	EPSD;PhosphoSitePlus	ICGC;COSMIC	6.466	Up-regulation
TK_EGFR_EGFR_Y	Q14164	IKBKE	P00533	EGFR	Y179	E177K	177	Missense	proximal	-2	no	10.842	7.662	PhosphoSitePlus;EPSD	ICGC;COSMIC	6.466	Down-regulation
TK_EGFR_EGFR_Y	Q14164	IKBKE	P00533	EGFR	Y179	Y179C	179	Missense	central	0	yes	10.842	0.000	PhosphoSitePlus;EPSD	ICGC;COSMIC	6.466	Loss
TK_EGFR_EGFR_Y	Q3V6T2	CCDC88A	P00533	EGFR	Y758	T751K	751	Missense	distal	-7	no	8.329	7.989	EPSD	ICGC	6.466	Down-regulation
TK_EGFR_EGFR_Y	Q3V6T2	CCDC88A	P00533	EGFR	Y1384	P1388S	1388	Missense	distal	4	no	6.874	6.312	EPSD	ICGC;COSMIC	6.466	Loss
TK_EGFR_EGFR_Y	Q92952	KCNN1	P00533	EGFR	Y109	R103Q	103	Missense	distal	-6	no	7.204	7.211	PhosphoSitePlus	ICGC;COSMIC	6.466	Up-regulation
TK_EGFR_EGFR_Y	Q92952	KCNN1	P00533	EGFR	Y109	M115I	115	Missense	distal	6	no	7.204	6.631	PhosphoSitePlus	ICGC	6.466	Down-regulation
TK_EGFR_EGFR_Y	Q9UKV8	AGO2	P00533	EGFR	Y393	R395C	395	Missense	proximal	2	no	8.879	8.676	PhosphoSitePlus	ICGC;COSMIC	6.466	Down-regulation
TK_EGFR_EGFR_Y	Q9UKV8	AGO2	P00533	EGFR	Y393	R395S	395	Missense	proximal	2	no	8.879	10.353	PhosphoSitePlus	ICGC	6.466	Up-regulation
TK_EGFR_EGFR_Y	Q9UKV8	AGO2	P00533	EGFR	Y749	T744A	744	Missense	distal	-5	no	9.529	9.587	EPSD	ICGC;COSMIC	6.466	Up-regulation
TK_EGFR_EGFR_Y	Q9UKV8	AGO2	P00533	EGFR	Y749	H753Y	753	Missense	distal	4	no	9.529	9.566	EPSD	ICGC;COSMIC	6.466	Up-regulation
STE_STE20_PAKA_PAK2_ST	Q53QZ3	ARHGAP15	Q13177	PAK2	S39	Q40K	40	Missense	proximal	1	no	13.884	15.167	EPSD	ICGC;COSMIC	14.606	Gain
STE_STE20_PAKA_PAK2_ST	Q53QZ3	ARHGAP15	Q13177	PAK2	S43	Q40K	40	Missense	distal	-3	no	1.256	18.118	PhosphoSitePlus;EPSD	ICGC;COSMIC	14.606	Gain
STE_STE20_PAKA_PAK2_ST	Q53QZ3	ARHGAP15	Q13177	PAK2	S211	Q208K	208	Missense	distal	-3	no	1.729	18.591	EPSD	ICGC	14.606	Gain
STE_STE20_PAKA_PAK2_ST	Q53QZ3	ARHGAP15	Q13177	PAK2	S233	R237S	237	Missense	distal	4	no	18.208	17.260	EPSD	ICGC;COSMIC	14.606	Down-regulation
STE_STE20_PAKA_PAK2_ST	Q53QZ3	ARHGAP15	Q13177	PAK2	S233	P228Q	228	Missense	distal	-5	no	18.208	16.847	EPSD	ICGC;COSMIC;GDSC;CCLE	14.606	Down-regulation
STE_STE20_PAKA_PAK2_ST	Q53QZ3	ARHGAP15	Q13177	PAK2	S241	R237S	237	Missense	distal	-4	no	19.522	20.124	EPSD	ICGC;COSMIC	14.606	Up-regulation
STE_STE20_PAKA_PAK2_ST	Q53QZ3	ARHGAP15	Q13177	PAK2	S241	S246G	246	Missense	distal	5	no	19.522	17.278	EPSD	ICGC	14.606	Down-regulation
STE_STE20_PAKA_PAK2_ST	Q53QZ3	ARHGAP15	Q13177	PAK2	S241	A242S	242	Missense	proximal	1	no	19.522	21.559	EPSD	ICGC;COSMIC	14.606	Up-regulation
STE_STE20_PAKA_PAK2_ST	Q53QZ3	ARHGAP15	Q13177	PAK2	S241	S246N	246	Missense	distal	5	no	19.522	20.202	EPSD	ICGC;COSMIC	14.606	Up-regulation
STE_STE20_PAKA_PAK2_ST	Q53QZ3	ARHGAP15	Q13177	PAK2	S241	T245K	245	Missense	distal	4	no	19.522	19.433	EPSD	ICGC;COSMIC	14.606	Down-regulation
STE_STE20_PAKA_PAK2_ST	Q53QZ3	ARHGAP15	Q13177	PAK2	S292	R289L	289	Missense	distal	-3	no	18.434	9.176	EPSD;PhosphoSitePlus	ICGC	14.606	Loss
STE_STE20_PAKA_PAK2_ST	Q53QZ3	ARHGAP15	Q13177	PAK2	S292	P295S	295	Missense	distal	3	no	18.434	13.448	EPSD;PhosphoSitePlus	ICGC	14.606	Loss
STE_STE20_PAKA_PAK2_ST	Q53QZ3	ARHGAP15	Q13177	PAK2	S292	R289C	289	Missense	distal	-3	no	18.434	1.254	EPSD;PhosphoSitePlus	ICGC;COSMIC	14.606	Loss
STE_STE20_PAKA_PAK2_ST	Q53QZ3	ARHGAP15	Q13177	PAK2	S343	N339T	339	Missense	distal	-4	no	24.999	23.490	EPSD	ICGC	14.606	Down-regulation
STE_STE20_PAKA_PAK2_ST	Q53QZ3	ARHGAP15	Q13177	PAK2	S343	E336D	336	Missense	distal	-7	no	24.999	25.893	EPSD	ICGC;COSMIC	14.606	Up-regulation
STE_STE20_PAKA_PAK2_ST	Q53QZ3	ARHGAP15	Q13177	PAK2	S393	V391A	391	Missense	proximal	-2	no	34.562	28.102	EPSD	ICGC	14.606	Down-regulation
STE_STE20_PAKA_PAK2_ST	Q53QZ3	ARHGAP15	Q13177	PAK2	S393	T386K	386	Missense	distal	-7	no	34.562	33.853	EPSD	ICGC;COSMIC	14.606	Down-regulation
STE_STE20_PAKA_PAK2_ST	Q53QZ3	ARHGAP15	Q13177	PAK2	S393	S393C	393	Missense	central	0	yes	34.562	0.000	EPSD	ICGC;COSMIC	14.606	Loss
STE_STE20_PAKA_PAK2_ST	Q53QZ3	ARHGAP15	Q13177	PAK2	S393	L398I	398	Missense	distal	5	no	34.562	31.751	EPSD	ICGC;COSMIC	14.606	Down-regulation
STE_STE20_PAKA_PAK2_ST	Q53QZ3	ARHGAP15	Q13177	PAK2	S393	R387G	387	Missense	distal	-6	no	34.562	30.019	EPSD	ICGC;COSMIC	14.606	Down-regulation
STE_STE20_PAKA_PAK2_ST	Q53QZ3	ARHGAP15	Q13177	PAK2	S393	P399H	399	Missense	distal	6	no	34.562	34.422	EPSD	ICGC;COSMIC	14.606	Down-regulation
STE_STE20_PAKA_PAK2_ST	Q13177	PAK2	Q13177	PAK2	S19	S20R	20	Missense	proximal	1	no	28.410	24.029	EPSD	ICGC;COSMIC	14.606	Down-regulation
STE_STE20_PAKA_PAK2_ST	Q13177	PAK2	Q13177	PAK2	S19	T25A	25	Missense	distal	6	no	28.410	28.300	EPSD	ICGC	14.606	Down-regulation
STE_STE20_PAKA_PAK2_ST	Q13177	PAK2	Q13177	PAK2	S20	S20R	20	Missense	central	0	yes	32.118	0.000	EPSD	ICGC;COSMIC	14.606	Loss
STE_STE20_PAKA_PAK2_ST	Q13177	PAK2	Q13177	PAK2	S20	T25A	25	Missense	distal	5	no	32.118	33.156	EPSD	ICGC	14.606	Up-regulation
STE_STE20_PAKA_PAK2_ST	Q13177	PAK2	Q13177	PAK2	S55	H51R	51	Missense	distal	-4	no	27.164	28.011	EPSD	ICGC	14.606	Up-regulation
STE_STE20_PAKA_PAK2_ST	Q13177	PAK2	Q13177	PAK2	S78	D79N	79	Missense	proximal	1	no	13.852	16.036	EPSD	ICGC;COSMIC	14.606	Gain
STE_STE20_PAKA_PAK2_ST	Q13177	PAK2	Q13177	PAK2	S109	I111V	111	Missense	proximal	2	no	12.095	15.591	EPSD	ICGC;COSMIC	14.606	Gain
STE_STE20_PAKA_PAK2_ST	Q13177	PAK2	Q13177	PAK2	S141	P145L	145	Missense	distal	4	no	32.805	31.008	EPSD	ICGC	14.606	Down-regulation
STE_STE20_PAKA_PAK2_ST	Q13177	PAK2	Q13177	PAK2	S141	V135L	135	Missense	distal	-6	no	32.805	33.997	EPSD	ICGC	14.606	Up-regulation
STE_STE20_PAKA_PAK2_ST	Q13177	PAK2	Q13177	PAK2	S141	S141I	141	Missense	central	0	yes	32.805	0.000	EPSD	ICGC;COSMIC	14.606	Loss
STE_STE20_PAKA_PAK2_ST	Q13177	PAK2	Q13177	PAK2	S192	T190M	190	Missense	proximal	-2	no	30.965	31.673	EPSD	ICGC;COSMIC	14.606	Up-regulation
STE_STE20_PAKA_PAK2_ST	Q13177	PAK2	Q13177	PAK2	S192	H189Y	189	Missense	distal	-3	no	30.965	36.360	EPSD	ICGC	14.606	Up-regulation
STE_STE20_PAKA_PAK2_ST	Q13177	PAK2	Q13177	PAK2	S197	T190M	190	Missense	distal	-7	no	23.729	23.555	EPSD	ICGC;COSMIC	14.606	Down-regulation
STE_STE20_PAKA_PAK2_ST	Q13177	PAK2	Q13177	PAK2	T402	W409C	409	Missense	distal	7	no	35.000	33.478	PhosphoSitePlus	ICGC	14.606	Down-regulation
STE_STE20_PAKA_PAK2_ST	Q13177	PAK2	Q13177	PAK2	S490	D484N	484	Missense	distal	-6	no	22.155	21.032	EPSD	ICGC	14.606	Down-regulation
STE_STE20_PAKA_PAK2_ST	P05412	JUN	Q13177	PAK2	T8	L14F	14	Missense	distal	6	no	19.613	20.367	PhosphoSitePlus;EPSD	ICGC;COSMIC	14.606	Up-regulation
STE_STE20_PAKA_PAK2_ST	P05412	JUN	Q13177	PAK2	T8	D11N	11	Missense	distal	3	no	19.613	16.272	PhosphoSitePlus;EPSD	ICGC	14.606	Down-regulation
STE_STE20_PAKA_PAK2_ST	P05412	JUN	Q13177	PAK2	T8	A3T	3	Missense	distal	-5	no	19.613	22.340	PhosphoSitePlus;EPSD	ICGC;COSMIC	14.606	Up-regulation
STE_STE20_PAKA_PAK2_ST	P05412	JUN	Q13177	PAK2	T8	N15K	15	Missense	distal	7	no	19.613	14.536	PhosphoSitePlus;EPSD	ICGC;COSMIC	14.606	Loss
STE_STE20_PAKA_PAK2_ST	P05412	JUN	Q13177	PAK2	T89	T93N	93	Missense	distal	4	no	33.388	34.074	EPSD;PhosphoSitePlus	ICGC	14.606	Up-regulation
STE_STE20_PAKA_PAK2_ST	P05412	JUN	Q13177	PAK2	T93	T93N	93	Missense	central	0	yes	24.978	0.000	EPSD;PhosphoSitePlus	ICGC	14.606	Loss
STE_STE20_PAKA_PAK2_ST	P05412	JUN	Q13177	PAK2	T93	L98R	98	Missense	distal	5	no	24.978	22.451	EPSD;PhosphoSitePlus	ICGC	14.606	Down-regulation
STE_STE20_PAKA_PAK2_ST	P05412	JUN	Q13177	PAK2	S243	T239K	239	Missense	distal	-4	no	17.257	16.768	EPSD	ICGC	14.606	Down-regulation
STE_STE20_PAKA_PAK2_ST	P05412	JUN	Q13177	PAK2	T286	E281Q	281	Missense	distal	-5	no	28.963	30.352	EPSD;PhosphoSitePlus	ICGC;COSMIC	14.606	Up-regulation
STE_STE20_PAKA_PAK2_ST	P05412	JUN	Q13177	PAK2	T286	R279Q	279	Missense	distal	-7	no	28.963	29.055	EPSD;PhosphoSitePlus	ICGC	14.606	Up-regulation
STE_STE20_PAKA_PAK2_ST	P05412	JUN	Q13177	PAK2	T286	L287V	287	Missense	proximal	1	no	28.963	29.463	EPSD;PhosphoSitePlus	ICGC;COSMIC	14.606	Up-regulation
STE_STE20_PAKA_PAK2_ST	P01106	MYC	Q13177	PAK2	S67	P72S	72	Missense	distal	5	no	17.246	18.793	EPSD	ICGC;COSMIC;GDSC	14.606	Up-regulation
STE_STE20_PAKA_PAK2_ST	P01106	MYC	Q13177	PAK2	S67	P72A	72	Missense	distal	5	no	17.246	19.356	EPSD	ICGC;COSMIC	14.606	Up-regulation
STE_STE20_PAKA_PAK2_ST	P01106	MYC	Q13177	PAK2	S67	P72L	72	Missense	distal	5	no	17.246	20.273	EPSD	ICGC;COSMIC	14.606	Up-regulation
STE_STE20_PAKA_PAK2_ST	P01106	MYC	Q13177	PAK2	S67	P72T	72	Missense	distal	5	no	17.246	18.318	EPSD	ICGC;COSMIC;GDSC	14.606	Up-regulation
STE_STE20_PAKA_PAK2_ST	P01106	MYC	Q13177	PAK2	S250	E257V	257	Missense	distal	7	no	17.884	21.883	EPSD	ICGC	14.606	Up-regulation
STE_STE20_PAKA_PAK2_ST	P01106	MYC	Q13177	PAK2	S373	Q380K	380	Missense	distal	7	no	32.787	27.052	EPSD;PhosphoSitePlus	ICGC;COSMIC	14.606	Down-regulation
STE_STE20_PAKA_PAK2_ST	P49023	PXN	Q13177	PAK2	S230	S226T	226	Missense	distal	-4	no	19.331	19.022	EPSD	ICGC;COSMIC	14.606	Down-regulation
STE_STE20_PAKA_PAK2_ST	P49023	PXN	Q13177	PAK2	S272	S272L	272	Missense	central	0	yes	29.251	0.000	PhosphoSitePlus;EPSD	ICGC;COSMIC;CCLE	14.606	Loss
STE_STE20_PAKA_PAK2_ST	P49023	PXN	Q13177	PAK2	S274	S272L	272	Missense	proximal	-2	no	31.516	36.372	EPSD;PhosphoSitePlus	ICGC;COSMIC;CCLE	14.606	Up-regulation
STE_STE20_PAKA_PAK2_ST	P49023	PXN	Q13177	PAK2	S320	S322L	322	Missense	proximal	2	no	19.499	15.796	EPSD	ICGC;COSMIC	14.606	Down-regulation
STE_STE20_PAKA_PAK2_ST	P49023	PXN	Q13177	PAK2	S332	P328L	328	Missense	distal	-4	no	24.417	23.964	EPSD	ICGC	14.606	Down-regulation
STE_STE20_PAKA_PAK2_ST	P55210	CASP7	Q13177	PAK2	T173	P178L	178	Missense	distal	5	no	29.180	32.206	EPSD;PhosphoSitePlus	ICGC	14.606	Up-regulation
STE_STE20_PAKA_PAK2_ST	Q16659	MAPK6	Q13177	PAK2	S450	S450L	450	Missense	central	0	yes	20.229	0.000	EPSD	ICGC;COSMIC	14.606	Loss
STE_STE20_PAKA_PAK2_ST	Q16659	MAPK6	Q13177	PAK2	S451	S450L	450	Missense	proximal	-1	no	25.098	27.723	EPSD	ICGC;COSMIC	14.606	Up-regulation
STE_STE20_PAKA_PAK2_ST	Q16659	MAPK6	Q13177	PAK2	T626	L629F	629	Missense	distal	3	no	16.415	17.548	EPSD	ICGC	14.606	Up-regulation
STE_STE20_PAKA_PAK2_ST	Q16659	MAPK6	Q13177	PAK2	S627	S634I	634	Missense	distal	7	no	13.391	17.575	EPSD	ICGC	14.606	Gain
STE_STE20_PAKA_PAK2_ST	Q16659	MAPK6	Q13177	PAK2	S627	L629F	629	Missense	proximal	2	no	13.391	21.167	EPSD	ICGC	14.606	Gain
STE_STE20_PAKA_PAK2_ST	Q16659	MAPK6	Q13177	PAK2	S704	I708S	708	Missense	distal	4	no	22.003	19.992	EPSD	ICGC;COSMIC	14.606	Down-regulation
STE_STE20_PAKA_PAK2_ST	Q16659	MAPK6	Q13177	PAK2	S704	M702I	702	Missense	proximal	-2	no	22.003	16.240	EPSD	ICGC;COSMIC	14.606	Down-regulation
STE_STE20_PAKA_PAK2_ST	Q16659	MAPK6	Q13177	PAK2	S704	P706S	706	Missense	proximal	2	no	22.003	28.915	EPSD	ICGC;COSMIC	14.606	Up-regulation
STE_STE20_PAKA_PAK2_ST	Q16659	MAPK6	Q13177	PAK2	S705	I708S	708	Missense	distal	3	no	17.680	12.441	EPSD	ICGC;COSMIC	14.606	Loss
STE_STE20_PAKA_PAK2_ST	Q16659	MAPK6	Q13177	PAK2	S705	M702I	702	Missense	distal	-3	no	17.680	10.010	EPSD	ICGC;COSMIC	14.606	Loss
STE_STE20_PAKA_PAK2_ST	Q16659	MAPK6	Q13177	PAK2	S705	P706S	706	Missense	proximal	1	no	17.680	20.002	EPSD	ICGC;COSMIC	14.606	Up-regulation
STE_STE20_PAKA_PAK2_ST	P00519	ABL1	Q13177	PAK2	S142	G144W	144	Missense	proximal	2	no	8.155	15.298	EPSD	ICGC	14.606	Gain
STE_STE20_PAKA_PAK2_ST	P00519	ABL1	Q13177	PAK2	S162	R161M	161	Missense	proximal	-1	no	7.766	15.350	EPSD	ICGC;COSMIC	14.606	Gain
STE_STE20_PAKA_PAK2_ST	P00519	ABL1	Q13177	PAK2	S265	T267M	267	Missense	proximal	2	no	17.594	15.760	EPSD	ICGC;COSMIC	14.606	Down-regulation
STE_STE20_PAKA_PAK2_ST	P00519	ABL1	Q13177	PAK2	T597	L599F	599	Missense	proximal	2	no	10.640	18.416	EPSD	ICGC	14.606	Gain
STE_STE20_PAKA_PAK2_ST	P00519	ABL1	Q13177	PAK2	T597	S601G	601	Missense	distal	4	no	10.640	15.055	EPSD	ICGC;COSMIC	14.606	Gain
STE_STE20_PAKA_PAK2_ST	P00519	ABL1	Q13177	PAK2	S618	R617C	617	Missense	proximal	-1	no	28.019	19.759	EPSD;PhosphoSitePlus	ICGC;COSMIC	14.606	Down-regulation
STE_STE20_PAKA_PAK2_ST	P00519	ABL1	Q13177	PAK2	S618	R617H	617	Missense	proximal	-1	no	28.019	22.658	EPSD;PhosphoSitePlus	ICGC;COSMIC	14.606	Down-regulation
STE_STE20_PAKA_PAK2_ST	P00519	ABL1	Q13177	PAK2	S618	M624I	624	Missense	distal	6	no	28.019	29.006	EPSD;PhosphoSitePlus	ICGC;COSMIC	14.606	Up-regulation
STE_STE20_PAKA_PAK2_ST	P00519	ABL1	Q13177	PAK2	S619	R617C	617	Missense	proximal	-2	no	51.499	39.898	PhosphoSitePlus;EPSD	ICGC;COSMIC	14.606	Down-regulation
STE_STE20_PAKA_PAK2_ST	P00519	ABL1	Q13177	PAK2	S619	R617H	617	Missense	proximal	-2	no	51.499	46.543	PhosphoSitePlus;EPSD	ICGC;COSMIC	14.606	Down-regulation
STE_STE20_PAKA_PAK2_ST	P00519	ABL1	Q13177	PAK2	S619	M624I	624	Missense	distal	5	no	51.499	48.423	PhosphoSitePlus;EPSD	ICGC;COSMIC	14.606	Down-regulation
STE_STE20_PAKA_PAK2_ST	P00519	ABL1	Q13177	PAK2	S663	G665V	665	Missense	proximal	2	no	14.971	24.667	EPSD	ICGC;COSMIC	14.606	Up-regulation
STE_STE20_PAKA_PAK2_ST	P00519	ABL1	Q13177	PAK2	S663	G665W	665	Missense	proximal	2	no	14.971	22.113	EPSD	ICGC;COSMIC	14.606	Up-regulation
STE_STE20_PAKA_PAK2_ST	P00519	ABL1	Q13177	PAK2	S691	T692M	692	Missense	proximal	1	no	14.268	16.393	EPSD	ICGC	14.606	Gain
STE_STE20_PAKA_PAK2_ST	P00519	ABL1	Q13177	PAK2	T779	V775A	775	Missense	distal	-4	no	14.837	13.429	EPSD	ICGC;COSMIC	14.606	Loss
STE_STE20_PAKA_PAK2_ST	P00519	ABL1	Q13177	PAK2	T779	P783S	783	Missense	distal	4	no	14.837	13.093	EPSD	ICGC	14.606	Loss
STE_STE20_PAKA_PAK2_ST	P00519	ABL1	Q13177	PAK2	T779	P784H	784	Missense	distal	5	no	14.837	18.191	EPSD	ICGC;COSMIC	14.606	Up-regulation
STE_STE20_PAKA_PAK2_ST	P00519	ABL1	Q13177	PAK2	T779	P784L	784	Missense	distal	5	no	14.837	17.864	EPSD	ICGC;COSMIC	14.606	Up-regulation
STE_STE20_PAKA_PAK2_ST	P00519	ABL1	Q13177	PAK2	S804	P806S	806	Missense	proximal	2	no	16.642	23.554	EPSD	ICGC;COSMIC	14.606	Up-regulation
STE_STE20_PAKA_PAK2_ST	P00519	ABL1	Q13177	PAK2	S804	P810L	810	Missense	distal	6	no	16.642	16.390	EPSD	ICGC;COSMIC	14.606	Down-regulation
STE_STE20_PAKA_PAK2_ST	P00519	ABL1	Q13177	PAK2	T963	P961S	961	Missense	proximal	-2	no	15.429	1.030	EPSD	ICGC;COSMIC	14.606	Loss
STE_STE20_PAKA_PAK2_ST	P00519	ABL1	Q13177	PAK2	T963	A969T	969	Missense	distal	6	no	15.429	15.539	EPSD	ICGC;COSMIC;CCLE	14.606	Up-regulation
STE_STE20_PAKA_PAK2_ST	P00519	ABL1	Q13177	PAK2	T963	P961L	961	Missense	proximal	-2	no	15.429	5.886	EPSD	ICGC;COSMIC	14.606	Loss
STE_STE20_PAKA_PAK2_ST	P00519	ABL1	Q13177	PAK2	S1125	E1123D	1123	Missense	proximal	-2	no	16.915	16.466	EPSD	ICGC;COSMIC	14.606	Down-regulation
STE_STE20_PAKA_PAK2_ST	P00519	ABL1	Q13177	PAK2	S1125	S1120L	1120	Missense	distal	-5	no	16.915	15.273	EPSD	ICGC;COSMIC	14.606	Down-regulation
STE_STE20_PAKA_PAK2_ST	P00519	ABL1	Q13177	PAK2	S1125	K1122M	1122	Missense	distal	-3	no	16.915	11.254	EPSD	ICGC;COSMIC	14.606	Loss
STE_STE20_PAKA_PAK2_ST	P35240	NF2	Q13177	PAK2	T251	W258C	258	Missense	distal	7	no	23.380	21.858	EPSD	ICGC	14.606	Down-regulation
STE_STE20_PAKA_PAK2_ST	P35240	NF2	Q13177	PAK2	S255	W258C	258	Missense	distal	3	no	24.681	24.471	EPSD	ICGC	14.606	Down-regulation
STE_STE20_PAKA_PAK2_ST	P35240	NF2	Q13177	PAK2	S265	W258C	258	Missense	distal	-7	no	26.682	24.953	EPSD	ICGC	14.606	Down-regulation
STE_STE20_PAKA_PAK2_ST	P35240	NF2	Q13177	PAK2	T415	R411C	411	Missense	distal	-4	no	16.554	17.098	EPSD	ICGC;COSMIC	14.606	Up-regulation
STE_STE20_PAKA_PAK2_ST	P35240	NF2	Q13177	PAK2	T415	M409I	409	Missense	distal	-6	no	16.554	11.825	EPSD	ICGC	14.606	Loss
STE_STE20_PAKA_PAK2_ST	P35240	NF2	Q13177	PAK2	S518	E520K	520	Missense	proximal	2	no	42.102	47.898	PhosphoSitePlus	ICGC;COSMIC	14.606	Up-regulation
STE_STE20_PAKA_PAK2_ST	P35240	NF2	Q13177	PAK2	S518	R516W	516	Missense	proximal	-2	no	42.102	12.177	PhosphoSitePlus	ICGC;COSMIC	14.606	Loss
STE_STE20_PAKA_PAK2_ST	P35240	NF2	Q13177	PAK2	S518	R516L	516	Missense	proximal	-2	no	42.102	23.233	PhosphoSitePlus	ICGC	14.606	Down-regulation
STE_STE20_PAKA_PAK2_ST	Q15796	SMAD2	Q13177	PAK2	S47	K53N	53	Missense	distal	6	no	21.511	20.707	EPSD	ICGC;COSMIC	14.606	Down-regulation
STE_STE20_PAKA_PAK2_ST	Q15796	SMAD2	Q13177	PAK2	T172	P173Q	173	Missense	proximal	1	no	19.293	18.290	EPSD	ICGC;COSMIC	14.606	Down-regulation
STE_STE20_PAKA_PAK2_ST	Q15796	SMAD2	Q13177	PAK2	S417	R415I	415	Missense	proximal	-2	no	32.504	19.713	PhosphoSitePlus	ICGC;COSMIC	14.606	Down-regulation
STE_STE20_PAKA_PAK2_ST	Q15796	SMAD2	Q13177	PAK2	T430	Q429K	429	Missense	proximal	-1	no	25.015	36.593	EPSD	ICGC	14.606	Up-regulation
STE_STE20_PAKA_PAK2_ST	Q04637	EIF4G1	Q13177	PAK2	S204	P208S	208	Missense	distal	4	no	27.843	26.098	EPSD	ICGC;COSMIC	14.606	Down-regulation
STE_STE20_PAKA_PAK2_ST	Q04637	EIF4G1	Q13177	PAK2	S204	P208H	208	Missense	distal	4	no	27.843	26.477	EPSD	ICGC;GDSC;CCLE	14.606	Down-regulation
STE_STE20_PAKA_PAK2_ST	Q04637	EIF4G1	Q13177	PAK2	S314	P310L	310	Missense	distal	-4	no	19.342	18.889	EPSD	ICGC;COSMIC	14.606	Down-regulation
STE_STE20_PAKA_PAK2_ST	Q04637	EIF4G1	Q13177	PAK2	S314	P310H	310	Missense	distal	-4	no	19.342	17.267	EPSD	ICGC;COSMIC	14.606	Down-regulation
STE_STE20_PAKA_PAK2_ST	Q04637	EIF4G1	Q13177	PAK2	S1092	A1086S	1086	Missense	distal	-6	no	28.254	25.741	EPSD	ICGC;COSMIC	14.606	Down-regulation
STE_STE20_PAKA_PAK2_ST	Q04637	EIF4G1	Q13177	PAK2	S1145	E1152D	1152	Missense	distal	7	no	29.958	34.638	EPSD	ICGC;COSMIC	14.606	Up-regulation
STE_STE20_PAKA_PAK2_ST	Q70Z35	PREX2	Q13177	PAK2	S1052	L1050F	1050	Missense	proximal	-2	no	15.309	-2.034	EPSD	ICGC	14.606	Loss
STE_STE20_PAKA_PAK2_ST	Q70Z35	PREX2	Q13177	PAK2	S1052	T1055A	1055	Missense	distal	3	no	15.309	15.356	EPSD	ICGC	14.606	Up-regulation
STE_STE20_PAKA_PAK2_ST	Q70Z35	PREX2	Q13177	PAK2	S1052	I1054K	1054	Missense	proximal	2	no	15.309	11.835	EPSD	ICGC;COSMIC	14.606	Loss
STE_STE20_PAKA_PAK2_ST	Q70Z35	PREX2	Q13177	PAK2	S1065	D1072E	1072	Missense	distal	7	no	23.060	18.380	EPSD	ICGC;COSMIC	14.606	Down-regulation
STE_STE20_PAKA_PAK2_ST	Q70Z35	PREX2	Q13177	PAK2	S1065	G1067D	1067	Missense	proximal	2	no	23.060	16.543	EPSD	ICGC	14.606	Down-regulation
STE_STE20_PAKA_PAK2_ST	Q70Z35	PREX2	Q13177	PAK2	S1107	I1102T	1102	Missense	distal	-5	no	36.962	37.652	PhosphoSitePlus	ICGC;COSMIC	14.606	Up-regulation
STE_STE20_PAKA_PAK2_ST	Q70Z35	PREX2	Q13177	PAK2	S1107	S1103I	1103	Missense	distal	-4	no	36.962	37.041	PhosphoSitePlus	ICGC	14.606	Up-regulation
STE_STE20_PAKA_PAK2_ST	Q70Z35	PREX2	Q13177	PAK2	S1107	S1103G	1103	Missense	distal	-4	no	36.962	37.795	PhosphoSitePlus	ICGC;COSMIC	14.606	Up-regulation
STE_STE20_PAKA_PAK2_ST	Q8IYU2	HACE1	Q13177	PAK2	T33	A30D	30	Missense	distal	-3	no	17.289	8.309	EPSD	ICGC;COSMIC	14.606	Loss
STE_STE20_PAKA_PAK2_ST	Q8IYU2	HACE1	Q13177	PAK2	T33	P36Q	36	Missense	distal	3	no	17.289	14.464	EPSD	ICGC	14.606	Loss
STE_STE20_PAKA_PAK2_ST	Q8IYU2	HACE1	Q13177	PAK2	S385	T389A	389	Missense	distal	4	no	35.489	34.494	PhosphoSitePlus	ICGC;COSMIC	14.606	Down-regulation
STE_STE20_PAKA_PAK2_ST	Q8IYU2	HACE1	Q13177	PAK2	S385	T389S	389	Missense	distal	4	no	35.489	33.980	PhosphoSitePlus	ICGC;COSMIC	14.606	Down-regulation
CMGC_MAPK_ERK7_MAPK15_ST	Q8TD08	MAPK15	Q8TD08	MAPK15	T175	A179T	179	Missense	distal	4	no	10.983	10.809	EPSD;PhosphoSitePlus	ICGC	5.395	Down-regulation
CMGC_MAPK_ERK7_MAPK15_ST	Q8TD08	MAPK15	Q8TD08	MAPK15	T175	A173V	173	Missense	proximal	-2	no	10.983	10.526	EPSD;PhosphoSitePlus	ICGC	5.395	Down-regulation
CMGC_MAPK_ERK7_MAPK15_ST	Q8TD08	MAPK15	Q8TD08	MAPK15	T175	P169L	169	Missense	distal	-6	no	10.983	11.148	EPSD;PhosphoSitePlus	ICGC	5.395	Up-regulation
CMGC_MAPK_ERK7_MAPK15_ST	Q8TD08	MAPK15	Q8TD08	MAPK15	S192	L197F	197	Missense	distal	5	no	10.763	10.390	EPSD;PhosphoSitePlus	ICGC;COSMIC	5.395	Down-regulation
CMGC_MAPK_ERK7_MAPK15_ST	Q8TD08	MAPK15	Q8TD08	MAPK15	S192	G198E	198	Missense	distal	6	no	10.763	10.029	EPSD;PhosphoSitePlus	ICGC	5.395	Down-regulation
CMGC_MAPK_ERK7_MAPK15_ST	Q8TD08	MAPK15	Q8TD08	MAPK15	S192	S191Y	191	Missense	proximal	-1	no	10.763	11.014	EPSD;PhosphoSitePlus	ICGC;COSMIC	5.395	Up-regulation
CMGC_MAPK_ERK7_MAPK15_ST	Q8TD08	MAPK15	Q8TD08	MAPK15	T352	E359K	359	Missense	distal	7	no	9.993	10.628	EPSD;PhosphoSitePlus	ICGC	5.395	Up-regulation
CMGC_MAPK_ERK7_MAPK15_ST	Q8TD08	MAPK15	Q8TD08	MAPK15	S362	E359K	359	Missense	distal	-3	no	9.448	9.698	EPSD;PhosphoSitePlus	ICGC	5.395	Up-regulation
CMGC_MAPK_ERK7_MAPK15_ST	Q8TD08	MAPK15	Q8TD08	MAPK15	S362	S362F	362	Missense	central	0	yes	9.448	0.000	EPSD;PhosphoSitePlus	ICGC;COSMIC;GDSC;CCLE	5.395	Loss
CMGC_MAPK_ERK7_MAPK15_ST	Q8TD08	MAPK15	Q8TD08	MAPK15	S379	L377P	377	Missense	proximal	-2	no	10.779	10.274	EPSD;PhosphoSitePlus	ICGC;COSMIC	5.395	Down-regulation
CMGC_MAPK_ERK7_MAPK15_ST	Q8TD08	MAPK15	Q8TD08	MAPK15	S379	Q376R	376	Missense	distal	-3	no	10.779	10.832	EPSD;PhosphoSitePlus	ICGC	5.395	Up-regulation
CMGC_MAPK_ERK7_MAPK15_ST	Q8TD08	MAPK15	Q8TD08	MAPK15	T381	L377P	377	Missense	distal	-4	no	10.411	10.358	PhosphoSitePlus;EPSD	ICGC;COSMIC	5.395	Down-regulation
CMGC_MAPK_ERK7_MAPK15_ST	Q8TD08	MAPK15	Q8TD08	MAPK15	T381	Q376R	376	Missense	distal	-5	no	10.411	9.946	PhosphoSitePlus;EPSD	ICGC	5.395	Down-regulation
CMGC_MAPK_ERK7_MAPK15_ST	P25963	NFKBIA	Q8TD08	MAPK15	S32	R29S	29	Missense	distal	-3	no	9.810	9.575	EPSD;PhosphoSitePlus	ICGC	5.395	Down-regulation
CMGC_MAPK_ERK7_MAPK15_ST	P25963	NFKBIA	Q8TD08	MAPK15	S32	D31G	31	Missense	proximal	-1	no	9.810	10.033	EPSD;PhosphoSitePlus	ICGC;COSMIC	5.395	Up-regulation
CMGC_MAPK_ERK7_MAPK15_ST	P25963	NFKBIA	Q8TD08	MAPK15	S32	K38T	38	Missense	distal	6	no	9.810	9.903	EPSD;PhosphoSitePlus	ICGC	5.395	Up-regulation
CMGC_MAPK_ERK7_MAPK15_ST	P25963	NFKBIA	Q8TD08	MAPK15	S36	R29S	29	Missense	distal	-7	no	10.289	10.544	PhosphoSitePlus;EPSD	ICGC	5.395	Up-regulation
CMGC_MAPK_ERK7_MAPK15_ST	P25963	NFKBIA	Q8TD08	MAPK15	S36	D31G	31	Missense	distal	-5	no	10.289	9.523	PhosphoSitePlus;EPSD	ICGC;COSMIC	5.395	Down-regulation
CMGC_MAPK_ERK7_MAPK15_ST	P25963	NFKBIA	Q8TD08	MAPK15	S36	K38T	38	Missense	proximal	2	no	10.289	10.288	PhosphoSitePlus;EPSD	ICGC	5.395	Down-regulation
CMGC_MAPK_ERK7_MAPK15_ST	P05412	JUN	Q8TD08	MAPK15	S63	K70T	70	Missense	distal	7	no	11.097	10.983	EPSD;PhosphoSitePlus	ICGC;COSMIC	5.395	Down-regulation
CMGC_MAPK_ERK7_MAPK15_ST	P05412	JUN	Q8TD08	MAPK15	S73	A72E	72	Missense	proximal	-1	no	11.823	11.523	PhosphoSitePlus;EPSD	ICGC;COSMIC	5.395	Down-regulation
CMGC_MAPK_ERK7_MAPK15_ST	P05412	JUN	Q8TD08	MAPK15	S73	K70T	70	Missense	distal	-3	no	11.823	11.819	PhosphoSitePlus;EPSD	ICGC;COSMIC	5.395	Down-regulation
CMGC_MAPK_ERK7_MAPK15_ST	P05412	JUN	Q8TD08	MAPK15	T89	T93N	93	Missense	distal	4	no	5.426	5.402	EPSD	ICGC	5.395	Down-regulation
TK_Ret_RET_Y	P27986	PIK3R1	P07949	RET	Y203	V197I	197	Missense	distal	-6	no	52.559	52.516	PhosphoSitePlus	ICGC;COSMIC	28.094	Down-regulation
TK_Ret_RET_Y	P07949	RET	P07949	RET	Y687	G691S	691	Missense	distal	4	no	50.930	52.471	EPSD;PhosphoSitePlus	ICGC;COSMIC	28.094	Up-regulation
TK_Ret_RET_Y	P07949	RET	P07949	RET	Y687	S686I	686	Missense	proximal	-1	no	50.930	51.130	EPSD;PhosphoSitePlus	ICGC	28.094	Up-regulation
TK_Ret_RET_Y	P07949	RET	P07949	RET	Y687	A680S	680	Missense	distal	-7	no	50.930	50.227	EPSD;PhosphoSitePlus	ICGC	28.094	Down-regulation
TK_Ret_RET_Y	P07949	RET	P07949	RET	Y687	A680T	680	Missense	distal	-7	no	50.930	52.058	EPSD;PhosphoSitePlus	ICGC;COSMIC;GDSC;CCLE	28.094	Up-regulation
TK_Ret_RET_Y	P07949	RET	P07949	RET	Y752	G748S	748	Missense	distal	-4	no	24.567	32.474	EPSD	ICGC;COSMIC	28.094	Gain
TK_Ret_RET_Y	P07949	RET	P07949	RET	Y826	S829I	829	Missense	distal	3	no	41.269	39.605	PhosphoSitePlus;EPSD	ICGC;COSMIC	28.094	Down-regulation
TK_Ret_RET_Y	P07949	RET	P07949	RET	Y826	R833L	833	Missense	distal	7	no	41.269	35.037	PhosphoSitePlus;EPSD	ICGC	28.094	Down-regulation
TK_Ret_RET_Y	P07949	RET	P07949	RET	Y826	G830E	830	Missense	distal	4	no	41.269	42.233	PhosphoSitePlus;EPSD	ICGC;COSMIC	28.094	Up-regulation
TK_Ret_RET_Y	P07949	RET	P07949	RET	Y900	G894V	894	Missense	distal	-6	no	36.527	36.566	EPSD;PhosphoSitePlus	ICGC	28.094	Up-regulation
TK_Ret_RET_Y	P07949	RET	P07949	RET	Y900	S904Y	904	Missense	distal	4	no	36.527	34.024	EPSD;PhosphoSitePlus	ICGC;COSMIC	28.094	Down-regulation
TK_Ret_RET_Y	P07949	RET	P07949	RET	Y900	K907N	907	Missense	distal	7	no	36.527	34.103	EPSD;PhosphoSitePlus	ICGC;COSMIC	28.094	Down-regulation
TK_Ret_RET_Y	P07949	RET	P07949	RET	Y905	S904Y	904	Missense	proximal	-1	no	53.485	53.686	EPSD;PhosphoSitePlus	ICGC;COSMIC	28.094	Up-regulation
TK_Ret_RET_Y	P07949	RET	P07949	RET	Y905	K907N	907	Missense	proximal	2	no	53.485	53.112	EPSD;PhosphoSitePlus	ICGC;COSMIC	28.094	Down-regulation
TK_Ret_RET_Y	P07949	RET	P07949	RET	Y981	E978K	978	Missense	distal	-3	no	39.068	39.105	EPSD;PhosphoSitePlus	ICGC;COSMIC	28.094	Up-regulation
TK_Ret_RET_Y	P07949	RET	P07949	RET	Y981	E978D	978	Missense	distal	-3	no	39.068	38.962	EPSD;PhosphoSitePlus	ICGC;COSMIC	28.094	Down-regulation
TK_Ret_RET_Y	P07949	RET	P07949	RET	Y981	R982L	982	Missense	proximal	1	no	39.068	39.986	EPSD;PhosphoSitePlus	ICGC	28.094	Up-regulation
TK_Ret_RET_Y	P07949	RET	P07949	RET	Y1015	L1016F	1016	Missense	proximal	1	no	48.606	45.988	EPSD;PhosphoSitePlus	ICGC;COSMIC	28.094	Down-regulation
TK_Ret_RET_Y	P07949	RET	P07949	RET	Y1015	A1019S	1019	Missense	distal	4	no	48.606	48.279	EPSD;PhosphoSitePlus	ICGC	28.094	Down-regulation
TK_Ret_RET_Y	P07949	RET	P07949	RET	Y1029	G1032S	1032	Missense	distal	3	no	38.638	40.138	EPSD;PhosphoSitePlus	ICGC;COSMIC	28.094	Up-regulation
TK_Ret_RET_Y	P07949	RET	P07949	RET	Y1062	W1056L	1056	Missense	distal	-6	no	59.960	59.988	EPSD;PhosphoSitePlus	ICGC	28.094	Up-regulation
TK_Ret_RET_Y	P07949	RET	P07949	RET	Y1090	A1097S	1097	Missense	distal	7	no	37.417	33.547	EPSD;PhosphoSitePlus	ICGC;COSMIC	28.094	Down-regulation
TK_Ret_RET_Y	P07949	RET	P07949	RET	Y1090	G1086A	1086	Missense	distal	-4	no	37.417	38.275	EPSD;PhosphoSitePlus	ICGC;COSMIC	28.094	Up-regulation
TK_Ret_RET_Y	P07949	RET	P07949	RET	Y1096	S1102P	1102	Missense	distal	6	no	59.110	58.672	EPSD;PhosphoSitePlus	ICGC	28.094	Down-regulation
TK_Ret_RET_Y	P07949	RET	P07949	RET	Y1096	A1097S	1097	Missense	proximal	1	no	59.110	59.604	EPSD;PhosphoSitePlus	ICGC;COSMIC	28.094	Up-regulation
TK_Ret_RET_Y	P07949	RET	P07949	RET	Y1096	W1099C	1099	Missense	distal	3	no	59.110	59.013	EPSD;PhosphoSitePlus	ICGC	28.094	Down-regulation
TK_Ret_RET_Y	O15530	PDPK1	P07949	RET	Y373	S366L	366	Missense	distal	-7	no	29.217	27.602	EPSD	ICGC	28.094	Loss
TK_Ret_RET_Y	Q99704	DOK1	P07949	RET	Y315	D312G	312	Missense	distal	-3	no	32.697	31.055	EPSD	ICGC	28.094	Down-regulation
TK_Ret_RET_Y	Q99704	DOK1	P07949	RET	Y315	S321I	321	Missense	distal	6	no	32.697	31.158	EPSD	ICGC;COSMIC	28.094	Down-regulation
TK_Ret_RET_Y	Q99704	DOK1	P07949	RET	Y449	L448M	448	Missense	proximal	-1	no	35.175	35.114	EPSD	ICGC;COSMIC	28.094	Down-regulation
TK_Ret_RET_Y	Q05397	PTK2	P07949	RET	Y861	P854L	854	Missense	distal	-7	no	43.327	39.745	EPSD;PhosphoSitePlus	ICGC;COSMIC	28.094	Down-regulation
TK_Ret_RET_Y	Q05397	PTK2	P07949	RET	Y861	H859Y	859	Missense	proximal	-2	no	43.327	41.829	EPSD;PhosphoSitePlus	ICGC;COSMIC	28.094	Down-regulation
TK_Ret_RET_Y	Q05397	PTK2	P07949	RET	Y898	S897Y	897	Missense	proximal	-1	no	32.715	32.916	EPSD	ICGC	28.094	Up-regulation
TK_Ret_RET_Y	Q05397	PTK2	P07949	RET	Y898	S897N	897	Missense	proximal	-1	no	32.715	32.802	EPSD	ICGC;COSMIC	28.094	Up-regulation
TK_Ret_RET_Y	Q05397	PTK2	P07949	RET	Y898	S897C	897	Missense	proximal	-1	no	32.715	32.879	EPSD	ICGC	28.094	Up-regulation
TK_Ret_RET_Y	P19174	PLCG1	P07949	RET	Y93	R100Q	100	Missense	distal	7	no	30.815	20.545	EPSD	ICGC;COSMIC	28.094	Loss
TK_Ret_RET_Y	P19174	PLCG1	P07949	RET	Y506	H503N	503	Missense	distal	-3	no	28.381	29.892	EPSD	ICGC	28.094	Up-regulation
TK_Ret_RET_Y	P19174	PLCG1	P07949	RET	Y771	R778H	778	Missense	distal	7	no	29.084	20.976	EPSD	ICGC;COSMIC	28.094	Loss
TK_Ret_RET_Y	P19174	PLCG1	P07949	RET	Y771	G772E	772	Missense	proximal	1	no	29.084	30.953	EPSD	ICGC	28.094	Up-regulation
TK_Ret_RET_Y	P19174	PLCG1	P07949	RET	Y771	A767V	767	Missense	distal	-4	no	29.084	33.130	EPSD	ICGC;COSMIC	28.094	Up-regulation
TK_Ret_RET_Y	P19174	PLCG1	P07949	RET	Y783	R778H	778	Missense	distal	-5	no	51.128	50.775	PhosphoSitePlus	ICGC;COSMIC	28.094	Down-regulation
TK_Ret_RET_Y	Q8N4X5	AFAP1L2	P07949	RET	Y54	Y56N	56	Missense	proximal	2	no	39.951	40.454	PhosphoSitePlus	ICGC;COSMIC	28.094	Up-regulation
TK_Ret_RET_Y	Q8N4X5	AFAP1L2	P07949	RET	Y54	E52D	52	Missense	proximal	-2	no	39.951	40.360	PhosphoSitePlus	ICGC;COSMIC	28.094	Up-regulation
TK_Ret_RET_Y	Q8N4X5	AFAP1L2	P07949	RET	Y124	T117M	117	Missense	distal	-7	no	30.292	26.197	EPSD	ICGC;COSMIC	28.094	Loss
TK_Ret_RET_Y	Q8N4X5	AFAP1L2	P07949	RET	Y124	A127V	127	Missense	distal	3	no	30.292	30.675	EPSD	ICGC;COSMIC	28.094	Up-regulation
TK_Ret_RET_Y	Q8N4X5	AFAP1L2	P07949	RET	Y413	F415V	415	Missense	proximal	2	no	30.679	31.670	EPSD	ICGC;COSMIC	28.094	Up-regulation
TK_Ret_RET_Y	Q8N4X5	AFAP1L2	P07949	RET	Y413	R416H	416	Missense	distal	3	no	30.679	29.540	EPSD	ICGC	28.094	Down-regulation
TK_Ret_RET_Y	Q8N4X5	AFAP1L2	P07949	RET	Y413	L412F	412	Missense	proximal	-1	no	30.679	30.792	EPSD	ICGC;COSMIC	28.094	Up-regulation
TK_Ret_RET_Y	Q8N4X5	AFAP1L2	P07949	RET	Y457	R464M	464	Missense	distal	7	no	38.835	31.602	EPSD	ICGC;COSMIC	28.094	Down-regulation
TK_Ret_RET_Y	Q8N4X5	AFAP1L2	P07949	RET	Y668	R674K	674	Missense	distal	6	no	34.635	34.853	EPSD	ICGC	28.094	Up-regulation
TK_Ret_RET_Y	Q8N4X5	AFAP1L2	P07949	RET	Y668	A663D	663	Missense	distal	-5	no	34.635	34.533	EPSD	ICGC	28.094	Down-regulation
TK_Ret_RET_Y	Q8N4X5	AFAP1L2	P07949	RET	Y668	E670D	670	Missense	proximal	2	no	34.635	34.733	EPSD	ICGC;COSMIC	28.094	Up-regulation
TK_Ret_RET_Y	Q8N4X5	AFAP1L2	P07949	RET	Y668	R667L	667	Missense	proximal	-1	no	34.635	34.624	EPSD	ICGC;COSMIC	28.094	Down-regulation
TK_Ret_RET_Y	P45984	MAPK9	P07949	RET	Y185	R192W	192	Missense	distal	7	no	56.127	50.411	PhosphoSitePlus	ICGC;COSMIC	28.094	Down-regulation
TK_Ret_RET_Y	P45984	MAPK9	P07949	RET	Y185	T188K	188	Missense	distal	3	no	56.127	56.007	PhosphoSitePlus	ICGC	28.094	Down-regulation
TK_Ret_RET_Y	P45984	MAPK9	P07949	RET	Y185	V186M	186	Missense	proximal	1	no	56.127	55.754	PhosphoSitePlus	ICGC	28.094	Down-regulation
TK_Ret_RET_Y	P28482	MAPK1	P07949	RET	Y25	L28I	28	Missense	distal	3	no	29.557	28.306	EPSD	ICGC	28.094	Down-regulation
TK_Ret_RET_Y	P28482	MAPK1	P07949	RET	Y25	R24C	24	Missense	proximal	-1	no	29.557	29.604	EPSD	ICGC	28.094	Up-regulation
TK_Ret_RET_Y	P28482	MAPK1	P07949	RET	Y187	T181K	181	Missense	distal	-6	no	57.218	57.235	PhosphoSitePlus	ICGC	28.094	Up-regulation
TK_Ret_RET_Y	P28482	MAPK1	P07949	RET	Y187	T185K	185	Missense	proximal	-2	no	57.218	55.849	PhosphoSitePlus	ICGC	28.094	Down-regulation
TK_Ret_RET_Y	P28482	MAPK1	P07949	RET	Y187	W192L	192	Missense	distal	5	no	57.218	57.264	PhosphoSitePlus	ICGC;COSMIC	28.094	Up-regulation
TK_Ret_RET_Y	P28482	MAPK1	P07949	RET	Y205	L200F	200	Missense	distal	-5	no	35.107	34.045	EPSD	ICGC;COSMIC	28.094	Down-regulation
TK_Ret_RET_Y	P45983	MAPK8	P07949	RET	Y185	R189P	189	Missense	distal	4	no	57.788	58.137	PhosphoSitePlus	ICGC;COSMIC	28.094	Up-regulation
TK_Ret_RET_Y	P45983	MAPK8	P07949	RET	Y185	S179I	179	Missense	distal	-6	no	57.788	57.712	PhosphoSitePlus	ICGC	28.094	Down-regulation
TK_Ret_RET_Y	P45983	MAPK8	P07949	RET	Y185	T183M	183	Missense	proximal	-2	no	57.788	55.681	PhosphoSitePlus	ICGC;COSMIC	28.094	Down-regulation
TK_Ret_RET_Y	P27361	MAPK3	P07949	RET	Y204	T198I	198	Missense	distal	-6	no	57.849	57.815	PhosphoSitePlus	ICGC;COSMIC	28.094	Down-regulation
TK_Ret_RET_Y	Q16539	MAPK14	P07949	RET	Y258	S254T	254	Missense	distal	-4	no	32.577	24.048	EPSD	ICGC;COSMIC	28.094	Loss
AGC_Akt_AKT1_ST	P19634	SLC9A1	P31749	AKT1	S648	R647Q	647	Missense	proximal	-1	no	15.140	15.108	PhosphoSitePlus;EPSD	ICGC;COSMIC;CCLE	7.780	Down-regulation
AGC_Akt_AKT1_ST	P19634	SLC9A1	P31749	AKT1	S648	Y649H	649	Missense	proximal	1	no	15.140	14.969	PhosphoSitePlus;EPSD	ICGC;COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	P19634	SLC9A1	P31749	AKT1	S703	G702S	702	Missense	proximal	-1	no	15.032	15.061	EPSD;PhosphoSitePlus	ICGC;COSMIC	7.780	Up-regulation
AGC_Akt_AKT1_ST	P19634	SLC9A1	P31749	AKT1	S703	R700S	700	Missense	distal	-3	no	15.032	7.255	EPSD;PhosphoSitePlus	ICGC	7.780	Loss
AGC_Akt_AKT1_ST	Q06187	BTK	P31749	AKT1	S21	K17T	17	Missense	distal	-4	no	8.937	8.921	EPSD	ICGC;COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	Q06187	BTK	P31749	AKT1	S21	S21L	21	Missense	central	0	yes	8.937	0.000	EPSD	ICGC	7.780	Loss
AGC_Akt_AKT1_ST	Q06187	BTK	P31749	AKT1	S21	P22H	22	Missense	proximal	1	no	8.937	8.915	EPSD	ICGC;COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	Q06187	BTK	P31749	AKT1	S51	S55A	55	Missense	distal	4	no	15.721	15.845	EPSD;PhosphoSitePlus	ICGC;COSMIC	7.780	Up-regulation
AGC_Akt_AKT1_ST	Q06187	BTK	P31749	AKT1	S51	R46C	46	Missense	distal	-5	no	15.721	11.644	EPSD;PhosphoSitePlus	ICGC;COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	Q06187	BTK	P31749	AKT1	S174	K176Q	176	Missense	proximal	2	no	13.063	12.758	EPSD	ICGC;COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	Q06187	BTK	P31749	AKT1	S310	V317G	317	Missense	distal	7	no	9.280	9.261	EPSD	ICGC;COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	Q06187	BTK	P31749	AKT1	S310	A312T	312	Missense	proximal	2	no	9.280	9.581	EPSD	ICGC	7.780	Up-regulation
AGC_Akt_AKT1_ST	Q06187	BTK	P31749	AKT1	S310	D308V	308	Missense	proximal	-2	no	9.280	9.483	EPSD	ICGC	7.780	Up-regulation
AGC_Akt_AKT1_ST	Q06187	BTK	P31749	AKT1	S310	I305F	305	Missense	distal	-5	no	9.280	10.325	EPSD	ICGC	7.780	Up-regulation
AGC_Akt_AKT1_ST	Q06187	BTK	P31749	AKT1	T495	R492H	492	Missense	distal	-3	no	14.279	9.581	PhosphoSitePlus;EPSD	ICGC;COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	Q06187	BTK	P31749	AKT1	T495	R492C	492	Missense	distal	-3	no	14.279	8.106	PhosphoSitePlus;EPSD	ICGC;COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	Q06187	BTK	P31749	AKT1	S623	T628N	628	Missense	distal	5	no	10.647	10.613	EPSD	ICGC	7.780	Down-regulation
AGC_Akt_AKT1_ST	Q06187	BTK	P31749	AKT1	S623	Y627S	627	Missense	distal	4	no	10.647	10.511	EPSD	ICGC;COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	Q9NR28	DIABLO	P31749	AKT1	S9	S6G	6	Missense	distal	-3	no	6.879	7.899	EPSD	ICGC	7.780	Gain
AGC_Akt_AKT1_ST	Q9NR28	DIABLO	P31749	AKT1	T13	R17G	17	Missense	distal	4	no	12.671	12.833	EPSD	ICGC	7.780	Up-regulation
AGC_Akt_AKT1_ST	Q9NR28	DIABLO	P31749	AKT1	T13	T13N	13	Missense	central	0	yes	12.671	0.000	EPSD	ICGC	7.780	Loss
AGC_Akt_AKT1_ST	Q9NR28	DIABLO	P31749	AKT1	T13	Q20P	20	Missense	distal	7	no	12.671	12.660	EPSD	ICGC;COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	Q9NR28	DIABLO	P31749	AKT1	T13	S6G	6	Missense	distal	-7	no	12.671	12.484	EPSD	ICGC	7.780	Down-regulation
AGC_Akt_AKT1_ST	Q9NR28	DIABLO	P31749	AKT1	S67	Q61H	61	Missense	distal	-6	no	8.220	8.186	PhosphoSitePlus	ICGC	7.780	Down-regulation
AGC_Akt_AKT1_ST	O43521	BCL2L11	P31749	AKT1	T34	S35F	35	Missense	proximal	1	no	8.560	8.578	EPSD	ICGC	7.780	Up-regulation
AGC_Akt_AKT1_ST	O43521	BCL2L11	P31749	AKT1	S87	R84G	84	Missense	distal	-3	no	10.333	3.577	PhosphoSitePlus	ICGC;COSMIC	7.780	Loss
AGC_Akt_AKT1_ST	O43521	BCL2L11	P31749	AKT1	S87	S92Y	92	Missense	distal	5	no	10.333	10.290	PhosphoSitePlus	ICGC	7.780	Down-regulation
AGC_Akt_AKT1_ST	O43521	BCL2L11	P31749	AKT1	S90	R84G	84	Missense	distal	-6	no	8.219	8.105	EPSD	ICGC;COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	O43521	BCL2L11	P31749	AKT1	S90	G95W	95	Missense	distal	5	no	8.219	8.194	EPSD	ICGC;COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	O43521	BCL2L11	P31749	AKT1	S90	S92Y	92	Missense	proximal	2	no	8.219	7.846	EPSD	ICGC	7.780	Down-regulation
AGC_Akt_AKT1_ST	O43521	BCL2L11	P31749	AKT1	S94	G95W	95	Missense	proximal	1	no	13.394	13.551	EPSD	ICGC;COSMIC	7.780	Up-regulation
AGC_Akt_AKT1_ST	O43521	BCL2L11	P31749	AKT1	S94	S92Y	92	Missense	proximal	-2	no	13.394	12.472	EPSD	ICGC	7.780	Down-regulation
AGC_Akt_AKT1_ST	O43521	BCL2L11	P31749	AKT1	S129	A123T	123	Missense	distal	-6	no	7.851	7.937	EPSD	ICGC;COSMIC	7.780	Up-regulation
AGC_Akt_AKT1_ST	P29474	NOS3	P31749	AKT1	S102	K108I	108	Missense	distal	6	no	10.188	10.014	EPSD	ICGC;COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	P29474	NOS3	P31749	AKT1	S102	S102F	102	Missense	central	0	yes	10.188	0.000	EPSD	ICGC	7.780	Loss
AGC_Akt_AKT1_ST	P29474	NOS3	P31749	AKT1	S102	R98C	98	Missense	distal	-4	no	10.188	8.510	EPSD	ICGC	7.780	Down-regulation
AGC_Akt_AKT1_ST	P29474	NOS3	P31749	AKT1	S260	G253V	253	Missense	distal	-7	no	7.871	7.779	EPSD	ICGC	7.780	Loss
AGC_Akt_AKT1_ST	P29474	NOS3	P31749	AKT1	S260	G263R	263	Missense	distal	3	no	7.871	7.945	EPSD	ICGC	7.780	Up-regulation
AGC_Akt_AKT1_ST	P29474	NOS3	P31749	AKT1	S260	D264G	264	Missense	distal	4	no	7.871	7.820	EPSD	ICGC	7.780	Down-regulation
AGC_Akt_AKT1_ST	P29474	NOS3	P31749	AKT1	T495	A500S	500	Missense	distal	5	no	11.190	11.241	EPSD	ICGC	7.780	Up-regulation
AGC_Akt_AKT1_ST	P29474	NOS3	P31749	AKT1	T495	A502S	502	Missense	distal	7	no	11.190	11.241	EPSD	ICGC	7.780	Up-regulation
AGC_Akt_AKT1_ST	P29474	NOS3	P31749	AKT1	T495	K493N	493	Missense	proximal	-2	no	11.190	10.253	EPSD	ICGC;COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	P29474	NOS3	P31749	AKT1	S615	S617P	617	Missense	proximal	2	no	11.942	11.605	PhosphoSitePlus;EPSD	ICGC;COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	P29474	NOS3	P31749	AKT1	S615	S608I	608	Missense	distal	-7	no	11.942	11.569	PhosphoSitePlus;EPSD	ICGC	7.780	Down-regulation
AGC_Akt_AKT1_ST	P29474	NOS3	P31749	AKT1	S615	P621T	621	Missense	distal	6	no	11.942	12.056	PhosphoSitePlus;EPSD	ICGC;COSMIC	7.780	Up-regulation
AGC_Akt_AKT1_ST	P29474	NOS3	P31749	AKT1	S633	R627W	627	Missense	distal	-6	no	17.774	17.627	EPSD	ICGC;COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	P29474	NOS3	P31749	AKT1	S633	R628W	628	Missense	distal	-5	no	17.774	12.255	EPSD	ICGC;COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	P29474	NOS3	P31749	AKT1	S634	R627W	627	Missense	distal	-7	no	10.558	10.135	EPSD	ICGC;COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	P29474	NOS3	P31749	AKT1	S634	R628W	628	Missense	distal	-6	no	10.558	10.411	EPSD	ICGC;COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	P29474	NOS3	P31749	AKT1	T785	R782C	782	Missense	distal	-3	no	9.168	2.995	EPSD	ICGC;COSMIC	7.780	Loss
AGC_Akt_AKT1_ST	P29474	NOS3	P31749	AKT1	T785	Q792P	792	Missense	distal	7	no	9.168	9.158	EPSD	ICGC;COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	P29474	NOS3	P31749	AKT1	T1175	Q1176E	1176	Missense	proximal	1	no	11.266	11.321	EPSD	ICGC;COSMIC	7.780	Up-regulation
AGC_Akt_AKT1_ST	P29474	NOS3	P31749	AKT1	S1177	Q1184H	1184	Missense	distal	7	no	17.081	17.065	EPSD;PhosphoSitePlus	ICGC;COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	P29474	NOS3	P31749	AKT1	S1177	Q1176E	1176	Missense	proximal	-1	no	17.081	17.089	EPSD;PhosphoSitePlus	ICGC;COSMIC	7.780	Up-regulation
AGC_Akt_AKT1_ST	P29474	NOS3	P31749	AKT1	S1179	Q1184H	1184	Missense	distal	5	no	11.305	11.282	EPSD	ICGC;COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	P29474	NOS3	P31749	AKT1	S1179	Q1176E	1176	Missense	distal	-3	no	11.305	11.945	EPSD	ICGC;COSMIC	7.780	Up-regulation
AGC_Akt_AKT1_ST	P29474	NOS3	P31749	AKT1	S1202	D1199H	1199	Missense	distal	-3	no	7.845	9.096	EPSD	ICGC	7.780	Up-regulation
AGC_Akt_AKT1_ST	Q86V81	ALYREF	P31749	AKT1	S194	R189Q	189	Missense	distal	-5	no	10.907	6.680	EPSD	ICGC	7.780	Loss
AGC_Akt_AKT1_ST	Q86V81	ALYREF	P31749	AKT1	S194	M200L	200	Missense	distal	6	no	10.907	10.902	EPSD	ICGC	7.780	Down-regulation
AGC_Akt_AKT1_ST	Q86V81	ALYREF	P31749	AKT1	S194	G199V	199	Missense	distal	5	no	10.907	10.911	EPSD	ICGC	7.780	Up-regulation
AGC_Akt_AKT1_ST	Q86V81	ALYREF	P31749	AKT1	S194	R190S	190	Missense	distal	-4	no	10.907	10.822	EPSD	ICGC	7.780	Down-regulation
AGC_Akt_AKT1_ST	Q86V81	ALYREF	P31749	AKT1	S194	R189W	189	Missense	distal	-5	no	10.907	5.387	EPSD	ICGC	7.780	Loss
AGC_Akt_AKT1_ST	Q86V81	ALYREF	P31749	AKT1	T219	G213A	213	Missense	distal	-6	no	11.247	11.271	EPSD;PhosphoSitePlus	ICGC	7.780	Up-regulation
AGC_Akt_AKT1_ST	Q86V81	ALYREF	P31749	AKT1	T219	G221R	221	Missense	proximal	2	no	11.247	11.407	EPSD;PhosphoSitePlus	ICGC	7.780	Up-regulation
AGC_Akt_AKT1_ST	Q86V81	ALYREF	P31749	AKT1	T219	R216Q	216	Missense	distal	-3	no	11.247	4.035	EPSD;PhosphoSitePlus	ICGC	7.780	Loss
AGC_Akt_AKT1_ST	Q86V81	ALYREF	P31749	AKT1	T219	R226G	226	Missense	distal	7	no	11.247	11.166	EPSD;PhosphoSitePlus	ICGC	7.780	Down-regulation
AGC_Akt_AKT1_ST	Q86V81	ALYREF	P31749	AKT1	T219	G212S	212	Missense	distal	-7	no	11.247	11.433	EPSD;PhosphoSitePlus	ICGC	7.780	Up-regulation
AGC_Akt_AKT1_ST	Q86V81	ALYREF	P31749	AKT1	T256	A252V	252	Missense	distal	-4	no	11.056	10.684	EPSD	ICGC	7.780	Down-regulation
AGC_Akt_AKT1_ST	Q86V81	ALYREF	P31749	AKT1	T256	A249V	249	Missense	distal	-7	no	11.056	10.927	EPSD	ICGC	7.780	Down-regulation
AGC_Akt_AKT1_ST	Q86V81	ALYREF	P31749	AKT1	T256	A252G	252	Missense	distal	-4	no	11.056	11.048	EPSD	ICGC	7.780	Down-regulation
AGC_Akt_AKT1_ST	P19484	TFEB	P31749	AKT1	S132	V130M	130	Missense	proximal	-2	no	7.737	8.087	EPSD	ICGC;COSMIC;GDSC	7.780	Gain
AGC_Akt_AKT1_ST	P19484	TFEB	P31749	AKT1	S227	A231T	231	Missense	distal	4	no	7.870	7.741	EPSD	ICGC;COSMIC	7.780	Loss
AGC_Akt_AKT1_ST	P19484	TFEB	P31749	AKT1	S227	K232N	232	Missense	distal	5	no	7.870	7.834	EPSD	ICGC;COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	P19484	TFEB	P31749	AKT1	T308	N309K	309	Missense	proximal	1	no	7.750	7.907	EPSD	ICGC	7.780	Gain
AGC_Akt_AKT1_ST	P19484	TFEB	P31749	AKT1	S463	R464H	464	Missense	proximal	1	no	11.685	11.362	EPSD	ICGC;COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	P19484	TFEB	P31749	AKT1	S463	S463R	463	Missense	central	0	yes	11.685	0.000	EPSD	ICGC	7.780	Loss
AGC_Akt_AKT1_ST	P19484	TFEB	P31749	AKT1	S463	R464P	464	Missense	proximal	1	no	11.685	11.385	EPSD	ICGC;COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	P19484	TFEB	P31749	AKT1	S463	R465L	465	Missense	proximal	2	no	11.685	11.312	EPSD	ICGC;COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	P19484	TFEB	P31749	AKT1	S466	S463R	463	Missense	distal	-3	no	7.716	15.493	EPSD	ICGC	7.780	Gain
AGC_Akt_AKT1_ST	P19484	TFEB	P31749	AKT1	S467	R464H	464	Missense	distal	-3	no	15.178	10.479	PhosphoSitePlus	ICGC;COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	P19484	TFEB	P31749	AKT1	S467	S463R	463	Missense	distal	-4	no	15.178	15.264	PhosphoSitePlus	ICGC	7.780	Up-regulation
AGC_Akt_AKT1_ST	P19484	TFEB	P31749	AKT1	S467	E472D	472	Missense	distal	5	no	15.178	15.136	PhosphoSitePlus	ICGC;COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	P19484	TFEB	P31749	AKT1	S467	R464P	464	Missense	distal	-3	no	15.178	8.538	PhosphoSitePlus	ICGC;COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	P19484	TFEB	P31749	AKT1	S467	R465L	465	Missense	proximal	-2	no	15.178	14.510	PhosphoSitePlus	ICGC;COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	P19484	TFEB	P31749	AKT1	S469	R464H	464	Missense	distal	-5	no	11.305	8.210	EPSD	ICGC;COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	P19484	TFEB	P31749	AKT1	S469	S463R	463	Missense	distal	-6	no	11.305	11.340	EPSD	ICGC	7.780	Up-regulation
AGC_Akt_AKT1_ST	P19484	TFEB	P31749	AKT1	S469	E472D	472	Missense	distal	3	no	11.305	11.235	EPSD	ICGC;COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	P19484	TFEB	P31749	AKT1	S469	R464P	464	Missense	distal	-5	no	11.305	7.295	EPSD	ICGC;COSMIC	7.780	Loss
AGC_Akt_AKT1_ST	P19484	TFEB	P31749	AKT1	S469	R465L	465	Missense	distal	-4	no	11.305	10.096	EPSD	ICGC;COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	P31749	AKT1	P31749	AKT1	T72	T65K	65	Missense	distal	-7	no	15.377	15.370	PhosphoSitePlus;EPSD	ICGC	7.780	Down-regulation
AGC_Akt_AKT1_ST	P31749	AKT1	P31749	AKT1	T92	H89R	89	Missense	distal	-3	no	6.769	11.468	EPSD	ICGC	7.780	Gain
AGC_Akt_AKT1_ST	P31749	AKT1	P31749	AKT1	T211	H207N	207	Missense	distal	-4	no	7.608	8.014	EPSD	ICGC;COSMIC	7.780	Gain
AGC_Akt_AKT1_ST	P31749	AKT1	P31749	AKT1	S246	D248H	248	Missense	proximal	2	no	15.300	15.366	EPSD;PhosphoSitePlus	ICGC;COSMIC	7.780	Up-regulation
AGC_Akt_AKT1_ST	P31749	AKT1	P31749	AKT1	S246	A250D	250	Missense	distal	4	no	15.300	15.401	EPSD;PhosphoSitePlus	ICGC	7.780	Up-regulation
AGC_Akt_AKT1_ST	P31749	AKT1	P31749	AKT1	S246	E242K	242	Missense	distal	-4	no	15.300	15.884	EPSD;PhosphoSitePlus	ICGC	7.780	Up-regulation
AGC_Akt_AKT1_ST	P31749	AKT1	P31749	AKT1	S246	V244A	244	Missense	proximal	-2	no	15.300	16.039	EPSD;PhosphoSitePlus	ICGC	7.780	Up-regulation
AGC_Akt_AKT1_ST	P31749	AKT1	P31749	AKT1	S246	R249W	249	Missense	distal	3	no	15.300	15.188	EPSD;PhosphoSitePlus	ICGC;COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	P31749	AKT1	P31749	AKT1	S246	R251S	251	Missense	distal	5	no	15.300	15.293	EPSD;PhosphoSitePlus	ICGC;COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	P31749	AKT1	P31749	AKT1	S422	K420T	420	Missense	proximal	-2	no	8.142	7.825	EPSD	ICGC	7.780	Down-regulation
AGC_Akt_AKT1_ST	P31749	AKT1	P31749	AKT1	S473	Q471K	471	Missense	proximal	-2	no	7.952	8.903	EPSD	ICGC	7.780	Up-regulation
AGC_Akt_AKT1_ST	P31749	AKT1	P31749	AKT1	S473	S477R	477	Missense	distal	4	no	7.952	7.963	EPSD	ICGC	7.780	Up-regulation
AGC_Akt_AKT1_ST	P31749	AKT1	P31749	AKT1	S475	Q471K	471	Missense	distal	-4	no	7.786	8.393	EPSD	ICGC	7.780	Up-regulation
AGC_Akt_AKT1_ST	P31749	AKT1	P31749	AKT1	S475	S477R	477	Missense	proximal	2	no	7.786	7.614	EPSD	ICGC	7.780	Loss
AGC_Akt_AKT1_ST	P19174	PLCG1	P31749	AKT1	T209	G206K	206	Missense	distal	-3	no	6.813	9.049	EPSD	ICGC	7.780	Gain
AGC_Akt_AKT1_ST	P19174	PLCG1	P31749	AKT1	T209	G206R	206	Missense	distal	-3	no	6.813	13.569	EPSD	ICGC	7.780	Gain
AGC_Akt_AKT1_ST	P19174	PLCG1	P31749	AKT1	S701	R707Q	707	Missense	distal	6	no	8.721	8.650	EPSD	ICGC;COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	P19174	PLCG1	P31749	AKT1	S701	A703V	703	Missense	proximal	2	no	8.721	8.559	EPSD	ICGC;COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	P19174	PLCG1	P31749	AKT1	S701	R694L	694	Missense	distal	-7	no	8.721	8.431	EPSD	ICGC	7.780	Down-regulation
AGC_Akt_AKT1_ST	P19174	PLCG1	P31749	AKT1	T932	E928K	928	Missense	distal	-4	no	7.641	8.225	EPSD	ICGC;COSMIC	7.780	Gain
AGC_Akt_AKT1_ST	P19174	PLCG1	P31749	AKT1	S981	P984Q	984	Missense	distal	3	no	10.532	10.540	EPSD	ICGC;COSMIC	7.780	Up-regulation
AGC_Akt_AKT1_ST	P19174	PLCG1	P31749	AKT1	S1248	R1252H	1252	Missense	distal	4	no	14.465	14.649	PhosphoSitePlus	ICGC;COSMIC;CCLE	7.780	Up-regulation
AGC_Akt_AKT1_ST	P19174	PLCG1	P31749	AKT1	S1248	R1245W	1245	Missense	distal	-3	no	14.465	5.524	PhosphoSitePlus	ICGC;COSMIC	7.780	Loss
AGC_Akt_AKT1_ST	P19174	PLCG1	P31749	AKT1	S1248	Q1255K	1255	Missense	distal	7	no	14.465	14.513	PhosphoSitePlus	ICGC;COSMIC	7.780	Up-regulation
AGC_Akt_AKT1_ST	P29375	KDM5A	P31749	AKT1	T285	R282W	282	Missense	distal	-3	no	16.140	7.200	EPSD;PhosphoSitePlus	ICGC;COSMIC	7.780	Loss
AGC_Akt_AKT1_ST	P29375	KDM5A	P31749	AKT1	T285	Q278K	278	Missense	distal	-7	no	16.140	16.321	EPSD;PhosphoSitePlus	ICGC	7.780	Up-regulation
AGC_Akt_AKT1_ST	P29375	KDM5A	P31749	AKT1	S287	R282W	282	Missense	distal	-5	no	10.380	4.860	PhosphoSitePlus;EPSD	ICGC;COSMIC	7.780	Loss
AGC_Akt_AKT1_ST	P29375	KDM5A	P31749	AKT1	T362	Q356P	356	Missense	distal	-6	no	10.750	10.736	EPSD	ICGC;COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	P29375	KDM5A	P31749	AKT1	T362	Q364K	364	Missense	proximal	2	no	10.750	11.056	EPSD	ICGC;COSMIC	7.780	Up-regulation
AGC_Akt_AKT1_ST	P29375	KDM5A	P31749	AKT1	T362	M369I	369	Missense	distal	7	no	10.750	10.711	EPSD	ICGC;COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	P29375	KDM5A	P31749	AKT1	S399	S400I	400	Missense	proximal	1	no	10.261	10.012	EPSD	ICGC	7.780	Down-regulation
AGC_Akt_AKT1_ST	P29375	KDM5A	P31749	AKT1	S811	S811R	811	Missense	central	0	yes	8.345	0.000	EPSD	ICGC;COSMIC	7.780	Loss
AGC_Akt_AKT1_ST	P29375	KDM5A	P31749	AKT1	S973	S970C	970	Missense	distal	-3	no	7.514	9.117	EPSD	ICGC;COSMIC	7.780	Gain
AGC_Akt_AKT1_ST	P29375	KDM5A	P31749	AKT1	S1067	Q1072R	1072	Missense	distal	5	no	8.000	8.050	EPSD	ICGC;COSMIC	7.780	Up-regulation
AGC_Akt_AKT1_ST	P29375	KDM5A	P31749	AKT1	S1075	Q1072R	1072	Missense	distal	-3	no	1.939	9.151	EPSD	ICGC;COSMIC	7.780	Gain
AGC_Akt_AKT1_ST	P29375	KDM5A	P31749	AKT1	T1225	L1229F	1229	Missense	distal	4	no	15.216	15.223	EPSD;PhosphoSitePlus	ICGC;COSMIC	7.780	Up-regulation
AGC_Akt_AKT1_ST	P29375	KDM5A	P31749	AKT1	S1255	W1256R	1256	Missense	proximal	1	no	12.019	12.311	EPSD;PhosphoSitePlus	ICGC;COSMIC	7.780	Up-regulation
AGC_Akt_AKT1_ST	P29375	KDM5A	P31749	AKT1	S1255	M1254I	1254	Missense	proximal	-1	no	12.019	11.998	EPSD;PhosphoSitePlus	ICGC;COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	P29375	KDM5A	P31749	AKT1	S1255	R1261L	1261	Missense	distal	6	no	12.019	11.916	EPSD;PhosphoSitePlus	ICGC;COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	P29375	KDM5A	P31749	AKT1	T1292	A1287G	1287	Missense	distal	-5	no	11.073	10.863	EPSD	ICGC;COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	P29375	KDM5A	P31749	AKT1	T1292	Q1286K	1286	Missense	distal	-6	no	11.073	11.143	EPSD	ICGC;COSMIC	7.780	Up-regulation
AGC_Akt_AKT1_ST	P29375	KDM5A	P31749	AKT1	S1326	R1323W	1323	Missense	distal	-3	no	11.803	2.862	EPSD	ICGC;COSMIC	7.780	Loss
AGC_Akt_AKT1_ST	P29375	KDM5A	P31749	AKT1	S1410	K1407N	1407	Missense	distal	-3	no	8.778	5.822	EPSD	ICGC;COSMIC	7.780	Loss
AGC_Akt_AKT1_ST	P49815	TSC2	P31749	AKT1	S311	S315L	315	Missense	distal	4	no	11.618	11.807	EPSD	ICGC;COSMIC	7.780	Up-regulation
AGC_Akt_AKT1_ST	P49815	TSC2	P31749	AKT1	S311	R308L	308	Missense	distal	-3	no	11.618	4.625	EPSD	ICGC;COSMIC	7.780	Loss
AGC_Akt_AKT1_ST	P49815	TSC2	P31749	AKT1	S311	A306D	306	Missense	distal	-5	no	11.618	11.427	EPSD	ICGC;COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	P49815	TSC2	P31749	AKT1	S540	R537L	537	Missense	distal	-3	no	11.290	4.296	EPSD	ICGC	7.780	Loss
AGC_Akt_AKT1_ST	P49815	TSC2	P31749	AKT1	S937	R934M	934	Missense	distal	-3	no	11.585	4.080	EPSD	ICGC;COSMIC	7.780	Loss
AGC_Akt_AKT1_ST	P49815	TSC2	P31749	AKT1	S939	R934M	934	Missense	distal	-5	no	15.360	10.838	EPSD;PhosphoSitePlus	ICGC;COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	P49815	TSC2	P31749	AKT1	S946	A950S	950	Missense	distal	4	no	10.866	10.742	EPSD	ICGC	7.780	Down-regulation
AGC_Akt_AKT1_ST	P49815	TSC2	P31749	AKT1	S979	R976Q	976	Missense	distal	-3	no	9.108	1.897	EPSD	ICGC;COSMIC	7.780	Loss
AGC_Akt_AKT1_ST	P49815	TSC2	P31749	AKT1	S979	R978C	978	Missense	proximal	-1	no	9.108	9.037	EPSD	ICGC;COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	P49815	TSC2	P31749	AKT1	S979	E973K	973	Missense	distal	-6	no	9.108	9.174	EPSD	ICGC;COSMIC	7.780	Up-regulation
AGC_Akt_AKT1_ST	P49815	TSC2	P31749	AKT1	S979	R976G	976	Missense	distal	-3	no	9.108	2.352	EPSD	ICGC	7.780	Loss
AGC_Akt_AKT1_ST	P49815	TSC2	P31749	AKT1	S979	V986M	986	Missense	distal	7	no	9.108	9.104	EPSD	ICGC	7.780	Down-regulation
AGC_Akt_AKT1_ST	P49815	TSC2	P31749	AKT1	S981	R976Q	976	Missense	distal	-5	no	14.283	10.055	EPSD;PhosphoSitePlus	ICGC;COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	P49815	TSC2	P31749	AKT1	S981	R978C	978	Missense	distal	-3	no	14.283	8.109	EPSD;PhosphoSitePlus	ICGC;COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	P49815	TSC2	P31749	AKT1	S981	R988L	988	Missense	distal	7	no	14.283	14.209	EPSD;PhosphoSitePlus	ICGC	7.780	Down-regulation
AGC_Akt_AKT1_ST	P49815	TSC2	P31749	AKT1	S981	R988H	988	Missense	distal	7	no	14.283	14.211	EPSD;PhosphoSitePlus	ICGC	7.780	Down-regulation
AGC_Akt_AKT1_ST	P49815	TSC2	P31749	AKT1	S981	R976G	976	Missense	distal	-5	no	14.283	10.218	EPSD;PhosphoSitePlus	ICGC	7.780	Down-regulation
AGC_Akt_AKT1_ST	P49815	TSC2	P31749	AKT1	S981	V986M	986	Missense	distal	5	no	14.283	14.286	EPSD;PhosphoSitePlus	ICGC	7.780	Up-regulation
AGC_Akt_AKT1_ST	P49815	TSC2	P31749	AKT1	S983	R976Q	976	Missense	distal	-7	no	9.011	8.816	EPSD	ICGC;COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	P49815	TSC2	P31749	AKT1	S983	R978C	978	Missense	distal	-5	no	9.011	4.934	EPSD	ICGC;COSMIC	7.780	Loss
AGC_Akt_AKT1_ST	P49815	TSC2	P31749	AKT1	S983	R988L	988	Missense	distal	5	no	9.011	8.937	EPSD	ICGC	7.780	Down-regulation
AGC_Akt_AKT1_ST	P49815	TSC2	P31749	AKT1	S983	R988H	988	Missense	distal	5	no	9.011	8.937	EPSD	ICGC	7.780	Down-regulation
AGC_Akt_AKT1_ST	P49815	TSC2	P31749	AKT1	S983	R976G	976	Missense	distal	-7	no	9.011	8.769	EPSD	ICGC	7.780	Down-regulation
AGC_Akt_AKT1_ST	P49815	TSC2	P31749	AKT1	S983	V986M	986	Missense	distal	3	no	9.011	9.015	EPSD	ICGC	7.780	Up-regulation
AGC_Akt_AKT1_ST	P49815	TSC2	P31749	AKT1	T993	R988L	988	Missense	distal	-5	no	12.911	8.785	EPSD	ICGC	7.780	Down-regulation
AGC_Akt_AKT1_ST	P49815	TSC2	P31749	AKT1	T993	R988H	988	Missense	distal	-5	no	12.911	9.816	EPSD	ICGC	7.780	Down-regulation
AGC_Akt_AKT1_ST	P49815	TSC2	P31749	AKT1	T993	V986M	986	Missense	distal	-7	no	12.911	12.972	EPSD	ICGC	7.780	Up-regulation
AGC_Akt_AKT1_ST	P49815	TSC2	P31749	AKT1	S1334	S1336L	1336	Missense	proximal	2	no	11.126	10.581	EPSD	ICGC;COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	P49815	TSC2	P31749	AKT1	S1338	S1336L	1336	Missense	proximal	-2	no	13.473	12.616	EPSD	ICGC;COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	P49815	TSC2	P31749	AKT1	S1340	S1336L	1336	Missense	distal	-4	no	9.262	8.138	EPSD	ICGC;COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	P49815	TSC2	P31749	AKT1	S1387	S1388L	1388	Missense	proximal	1	no	8.028	8.127	EPSD	ICGC;COSMIC	7.780	Up-regulation
AGC_Akt_AKT1_ST	Q15633	TARBP2	P31749	AKT1	T10	S8C	8	Missense	proximal	-2	no	8.005	6.352	EPSD	ICGC	7.780	Loss
AGC_Akt_AKT1_ST	P14618	PKM	P31749	AKT1	S6	P4T	4	Missense	proximal	-2	no	8.617	9.375	EPSD	ICGC	7.780	Up-regulation
AGC_Akt_AKT1_ST	P14618	PKM	P31749	AKT1	T10	Q14E	14	Missense	distal	4	no	8.264	8.208	EPSD	ICGC;COSMIC;GDSC;CCLE	7.780	Down-regulation
AGC_Akt_AKT1_ST	P14618	PKM	P31749	AKT1	T10	Q14K	14	Missense	distal	4	no	8.264	8.107	EPSD	ICGC;COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	P14618	PKM	P31749	AKT1	T10	P4T	4	Missense	distal	-6	no	8.264	8.359	EPSD	ICGC	7.780	Up-regulation
AGC_Akt_AKT1_ST	P14618	PKM	P31749	AKT1	S37	D34E	34	Missense	distal	-3	no	8.626	8.005	PhosphoSitePlus;EPSD	ICGC	7.780	Down-regulation
AGC_Akt_AKT1_ST	P14618	PKM	P31749	AKT1	S37	P38T	38	Missense	proximal	1	no	8.626	8.974	PhosphoSitePlus;EPSD	ICGC	7.780	Up-regulation
AGC_Akt_AKT1_ST	P14618	PKM	P31749	AKT1	S249	A248G	248	Missense	proximal	-1	no	11.640	11.631	EPSD	ICGC	7.780	Down-regulation
AGC_Akt_AKT1_ST	P02545	LMNA	P31749	AKT1	T10	G13E	13	Missense	distal	3	no	13.130	13.180	EPSD	ICGC	7.780	Up-regulation
AGC_Akt_AKT1_ST	P02545	LMNA	P31749	AKT1	S12	G13E	13	Missense	proximal	1	no	12.055	12.264	EPSD	ICGC	7.780	Up-regulation
AGC_Akt_AKT1_ST	P02545	LMNA	P31749	AKT1	S51	R50L	50	Missense	proximal	-1	no	8.659	8.620	EPSD	ICGC;COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	P02545	LMNA	P31749	AKT1	S149	A151T	151	Missense	proximal	2	no	8.537	8.838	EPSD	ICGC;COSMIC	7.780	Up-regulation
AGC_Akt_AKT1_ST	P02545	LMNA	P31749	AKT1	S268	E262D	262	Missense	distal	-6	no	7.922	7.850	EPSD	ICGC	7.780	Down-regulation
AGC_Akt_AKT1_ST	P02545	LMNA	P31749	AKT1	S458	D461G	461	Missense	distal	3	no	14.905	14.925	EPSD	ICGC	7.780	Up-regulation
AGC_Akt_AKT1_ST	P02545	LMNA	P31749	AKT1	S546	R545C	545	Missense	proximal	-1	no	8.312	8.242	EPSD	ICGC;COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	P02545	LMNA	P31749	AKT1	S546	R545L	545	Missense	proximal	-1	no	8.312	8.274	EPSD	ICGC	7.780	Down-regulation
AGC_Akt_AKT1_ST	P02545	LMNA	P31749	AKT1	T548	R545C	545	Missense	distal	-3	no	11.111	4.938	EPSD	ICGC;COSMIC	7.780	Loss
AGC_Akt_AKT1_ST	P02545	LMNA	P31749	AKT1	T548	R545L	545	Missense	distal	-3	no	11.111	4.117	EPSD	ICGC	7.780	Loss
AGC_Akt_AKT1_ST	P38398	BRCA1	P31749	AKT1	S76	V83F	83	Missense	distal	7	no	10.091	10.073	EPSD	ICGC;COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	P38398	BRCA1	P31749	AKT1	S76	Q74K	74	Missense	proximal	-2	no	10.091	11.043	EPSD	ICGC	7.780	Up-regulation
AGC_Akt_AKT1_ST	P38398	BRCA1	P31749	AKT1	S76	L82I	82	Missense	distal	6	no	10.091	10.031	EPSD	ICGC	7.780	Down-regulation
AGC_Akt_AKT1_ST	P38398	BRCA1	P31749	AKT1	S76	S80R	80	Missense	distal	4	no	10.091	10.102	EPSD	ICGC	7.780	Up-regulation
AGC_Akt_AKT1_ST	P38398	BRCA1	P31749	AKT1	T509	R507T	507	Missense	proximal	-2	no	15.352	15.474	PhosphoSitePlus;EPSD	ICGC;COSMIC	7.780	Up-regulation
AGC_Akt_AKT1_ST	P38398	BRCA1	P31749	AKT1	S510	R507T	507	Missense	distal	-3	no	13.497	6.476	EPSD	ICGC;COSMIC	7.780	Loss
AGC_Akt_AKT1_ST	P38398	BRCA1	P31749	AKT1	S615	N609I	609	Missense	distal	-6	no	16.200	16.126	EPSD	ICGC	7.780	Down-regulation
AGC_Akt_AKT1_ST	P38398	BRCA1	P31749	AKT1	S616	N609I	609	Missense	distal	-7	no	12.943	12.685	EPSD	ICGC	7.780	Down-regulation
AGC_Akt_AKT1_ST	P38398	BRCA1	P31749	AKT1	S632	N635K	635	Missense	distal	3	no	11.231	11.290	EPSD	ICGC	7.780	Up-regulation
AGC_Akt_AKT1_ST	P38398	BRCA1	P31749	AKT1	S1191	H1197N	1197	Missense	distal	6	no	11.771	11.824	EPSD	ICGC;COSMIC	7.780	Up-regulation
AGC_Akt_AKT1_ST	P38398	BRCA1	P31749	AKT1	S1211	L1216F	1216	Missense	distal	5	no	9.013	9.007	EPSD	ICGC;COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	Q16584	MAP3K11	P31749	AKT1	S19	W16R	16	Missense	distal	-3	no	3.491	12.431	EPSD	ICGC;COSMIC	7.780	Gain
AGC_Akt_AKT1_ST	Q16584	MAP3K11	P31749	AKT1	S21	W16R	16	Missense	distal	-5	no	4.158	9.678	EPSD	ICGC;COSMIC	7.780	Gain
AGC_Akt_AKT1_ST	Q16584	MAP3K11	P31749	AKT1	T477	R473H	473	Missense	distal	-4	no	16.251	15.192	EPSD	ICGC;COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	Q16584	MAP3K11	P31749	AKT1	T477	G476R	476	Missense	proximal	-1	no	16.251	16.291	EPSD	ICGC	7.780	Up-regulation
AGC_Akt_AKT1_ST	Q16584	MAP3K11	P31749	AKT1	T477	R472C	472	Missense	distal	-5	no	16.251	12.174	EPSD	ICGC;COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	Q16584	MAP3K11	P31749	AKT1	S674	P675L	675	Missense	proximal	1	no	16.907	17.160	PhosphoSitePlus	ICGC;COSMIC	7.780	Up-regulation
AGC_Akt_AKT1_ST	Q16584	MAP3K11	P31749	AKT1	S674	R671C	671	Missense	distal	-3	no	16.907	10.733	PhosphoSitePlus	ICGC;COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	Q16584	MAP3K11	P31749	AKT1	T752	T752A	752	Missense	central	0	yes	8.094	0.000	EPSD	ICGC	7.780	Loss
AGC_Akt_AKT1_ST	Q16584	MAP3K11	P31749	AKT1	T752	G751S	751	Missense	proximal	-1	no	8.094	8.124	EPSD	ICGC	7.780	Up-regulation
AGC_Akt_AKT1_ST	Q16584	MAP3K11	P31749	AKT1	S780	G785R	785	Missense	distal	5	no	8.768	8.838	EPSD	ICGC	7.780	Up-regulation
AGC_Akt_AKT1_ST	P55211	CASP9	P31749	AKT1	S99	Q94K	94	Missense	distal	-5	no	6.214	8.044	EPSD	ICGC	7.780	Gain
AGC_Akt_AKT1_ST	P55211	CASP9	P31749	AKT1	T125	L121I	121	Missense	distal	-4	no	10.550	10.292	EPSD	ICGC;COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	P55211	CASP9	P31749	AKT1	T181	I185V	185	Missense	distal	4	no	11.872	11.791	EPSD	ICGC;COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	P55211	CASP9	P31749	AKT1	T181	R180C	180	Missense	proximal	-1	no	11.872	11.802	EPSD	ICGC;COSMIC;GDSC;CCLE	7.780	Down-regulation
AGC_Akt_AKT1_ST	P55211	CASP9	P31749	AKT1	T181	R178C	178	Missense	distal	-3	no	11.872	5.699	EPSD	ICGC;COSMIC;GDSC	7.780	Loss
AGC_Akt_AKT1_ST	P55211	CASP9	P31749	AKT1	T181	R178S	178	Missense	distal	-3	no	11.872	4.096	EPSD	ICGC;COSMIC	7.780	Loss
AGC_Akt_AKT1_ST	P55211	CASP9	P31749	AKT1	T181	D186N	186	Missense	distal	5	no	11.872	11.913	EPSD	ICGC	7.780	Up-regulation
AGC_Akt_AKT1_ST	P55211	CASP9	P31749	AKT1	S183	I185V	185	Missense	proximal	2	no	17.682	17.800	EPSD	ICGC;COSMIC	7.780	Up-regulation
AGC_Akt_AKT1_ST	P55211	CASP9	P31749	AKT1	S183	R180C	180	Missense	distal	-3	no	17.682	11.509	EPSD	ICGC;COSMIC;GDSC;CCLE	7.780	Down-regulation
AGC_Akt_AKT1_ST	P55211	CASP9	P31749	AKT1	S183	R178C	178	Missense	distal	-5	no	17.682	13.605	EPSD	ICGC;COSMIC;GDSC	7.780	Down-regulation
AGC_Akt_AKT1_ST	P55211	CASP9	P31749	AKT1	S183	R178S	178	Missense	distal	-5	no	17.682	13.212	EPSD	ICGC;COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	P55211	CASP9	P31749	AKT1	S183	D186N	186	Missense	distal	3	no	17.682	17.738	EPSD	ICGC	7.780	Up-regulation
AGC_Akt_AKT1_ST	O60343	TBC1D4	P31749	AKT1	S66	R63H	63	Missense	distal	-3	no	11.471	6.772	EPSD	ICGC;COSMIC	7.780	Loss
AGC_Akt_AKT1_ST	O60343	TBC1D4	P31749	AKT1	S66	A60T	60	Missense	distal	-6	no	11.471	11.557	EPSD	ICGC	7.780	Up-regulation
AGC_Akt_AKT1_ST	O60343	TBC1D4	P31749	AKT1	S66	S66N	66	Missense	central	0	yes	11.471	0.000	EPSD	ICGC;COSMIC	7.780	Loss
AGC_Akt_AKT1_ST	O60343	TBC1D4	P31749	AKT1	S220	D223N	223	Missense	distal	3	no	7.997	8.053	EPSD	ICGC;COSMIC	7.780	Up-regulation
AGC_Akt_AKT1_ST	O60343	TBC1D4	P31749	AKT1	S220	M226T	226	Missense	distal	6	no	7.997	8.117	EPSD	ICGC;COSMIC	7.780	Up-regulation
AGC_Akt_AKT1_ST	O60343	TBC1D4	P31749	AKT1	S220	S220R	220	Missense	central	0	yes	7.997	0.000	EPSD	ICGC	7.780	Loss
AGC_Akt_AKT1_ST	O60343	TBC1D4	P31749	AKT1	S220	A217D	217	Missense	distal	-3	no	7.997	8.350	EPSD	ICGC	7.780	Up-regulation
AGC_Akt_AKT1_ST	O60343	TBC1D4	P31749	AKT1	S220	T213N	213	Missense	distal	-7	no	7.997	7.833	EPSD	ICGC	7.780	Down-regulation
AGC_Akt_AKT1_ST	O60343	TBC1D4	P31749	AKT1	S330	H327Q	327	Missense	distal	-3	no	10.553	8.041	EPSD	ICGC;COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	O60343	TBC1D4	P31749	AKT1	S330	Q331K	331	Missense	proximal	1	no	10.553	10.771	EPSD	ICGC;COSMIC	7.780	Up-regulation
AGC_Akt_AKT1_ST	O60343	TBC1D4	P31749	AKT1	S330	P335S	335	Missense	distal	5	no	10.553	10.606	EPSD	ICGC	7.780	Up-regulation
AGC_Akt_AKT1_ST	O60343	TBC1D4	P31749	AKT1	S341	A340T	340	Missense	proximal	-1	no	16.535	16.562	EPSD;PhosphoSitePlus	ICGC;COSMIC	7.780	Up-regulation
AGC_Akt_AKT1_ST	O60343	TBC1D4	P31749	AKT1	S341	Q347E	347	Missense	distal	6	no	16.535	16.549	EPSD;PhosphoSitePlus	ICGC;COSMIC	7.780	Up-regulation
AGC_Akt_AKT1_ST	O60343	TBC1D4	P31749	AKT1	S341	P335S	335	Missense	distal	-6	no	16.535	16.599	EPSD;PhosphoSitePlus	ICGC	7.780	Up-regulation
AGC_Akt_AKT1_ST	O60343	TBC1D4	P31749	AKT1	S341	A340V	340	Missense	proximal	-1	no	16.535	16.521	EPSD;PhosphoSitePlus	ICGC;COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	O60343	TBC1D4	P31749	AKT1	T568	N561H	561	Missense	distal	-7	no	12.685	12.553	EPSD;PhosphoSitePlus	ICGC	7.780	Down-regulation
AGC_Akt_AKT1_ST	O60343	TBC1D4	P31749	AKT1	T568	K562R	562	Missense	distal	-6	no	12.685	12.699	EPSD;PhosphoSitePlus	ICGC	7.780	Up-regulation
AGC_Akt_AKT1_ST	O60343	TBC1D4	P31749	AKT1	S588	L586I	586	Missense	proximal	-2	no	14.745	14.361	EPSD;PhosphoSitePlus	ICGC	7.780	Down-regulation
AGC_Akt_AKT1_ST	O60343	TBC1D4	P31749	AKT1	S588	R585Q	585	Missense	distal	-3	no	14.745	7.534	EPSD;PhosphoSitePlus	ICGC	7.780	Loss
AGC_Akt_AKT1_ST	O60343	TBC1D4	P31749	AKT1	S588	R585G	585	Missense	distal	-3	no	14.745	7.989	EPSD;PhosphoSitePlus	ICGC	7.780	Down-regulation
AGC_Akt_AKT1_ST	O60343	TBC1D4	P31749	AKT1	S597	L598I	598	Missense	proximal	1	no	12.000	11.653	EPSD	ICGC;COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	O60343	TBC1D4	P31749	AKT1	S597	N596K	596	Missense	proximal	-1	no	12.000	12.024	EPSD	ICGC	7.780	Up-regulation
AGC_Akt_AKT1_ST	O60343	TBC1D4	P31749	AKT1	T642	Q635K	635	Missense	distal	-7	no	16.897	17.079	EPSD;PhosphoSitePlus	ICGC	7.780	Up-regulation
AGC_Akt_AKT1_ST	O60343	TBC1D4	P31749	AKT1	T642	P646Q	646	Missense	distal	4	no	16.897	16.876	EPSD;PhosphoSitePlus	ICGC;COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	O60343	TBC1D4	P31749	AKT1	S644	P646Q	646	Missense	proximal	2	no	11.295	11.342	EPSD	ICGC;COSMIC	7.780	Up-regulation
AGC_Akt_AKT1_ST	Q2PPJ7	RALGAPA2	P31749	AKT1	S362	T355M	355	Missense	distal	-7	no	8.057	7.791	EPSD	ICGC;COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	Q2PPJ7	RALGAPA2	P31749	AKT1	S469	G474C	474	Missense	distal	5	no	8.075	8.019	EPSD	ICGC;COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	Q2PPJ7	RALGAPA2	P31749	AKT1	S469	S465I	465	Missense	distal	-4	no	8.075	6.694	EPSD	ICGC;COSMIC	7.780	Loss
AGC_Akt_AKT1_ST	Q2PPJ7	RALGAPA2	P31749	AKT1	S469	S470Y	470	Missense	proximal	1	no	8.075	8.068	EPSD	ICGC;COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	Q2PPJ7	RALGAPA2	P31749	AKT1	S478	T484K	484	Missense	distal	6	no	8.596	8.586	EPSD	ICGC;COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	Q2PPJ7	RALGAPA2	P31749	AKT1	S478	G474C	474	Missense	distal	-4	no	8.596	7.732	EPSD	ICGC;COSMIC	7.780	Loss
AGC_Akt_AKT1_ST	Q2PPJ7	RALGAPA2	P31749	AKT1	S480	T484K	484	Missense	distal	4	no	13.486	13.469	EPSD	ICGC;COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	Q2PPJ7	RALGAPA2	P31749	AKT1	S480	G474C	474	Missense	distal	-6	no	13.486	13.419	EPSD	ICGC;COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	Q2PPJ7	RALGAPA2	P31749	AKT1	S486	S492N	492	Missense	distal	6	no	9.893	9.825	EPSD;PhosphoSitePlus	ICGC;COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	Q2PPJ7	RALGAPA2	P31749	AKT1	S486	T484K	484	Missense	proximal	-2	no	9.893	10.210	EPSD;PhosphoSitePlus	ICGC;COSMIC	7.780	Up-regulation
AGC_Akt_AKT1_ST	Q2PPJ7	RALGAPA2	P31749	AKT1	S696	R700W	700	Missense	distal	4	no	11.600	11.847	EPSD	ICGC	7.780	Up-regulation
AGC_Akt_AKT1_ST	Q2PPJ7	RALGAPA2	P31749	AKT1	S696	W699C	699	Missense	distal	3	no	11.600	11.551	EPSD	ICGC;COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	Q2PPJ7	RALGAPA2	P31749	AKT1	S696	G692W	692	Missense	distal	-4	no	11.600	10.866	EPSD	ICGC;COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	Q2PPJ7	RALGAPA2	P31749	AKT1	S696	G692V	692	Missense	distal	-4	no	11.600	11.235	EPSD	ICGC;COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	Q2PPJ7	RALGAPA2	P31749	AKT1	S698	R700W	700	Missense	proximal	2	no	10.338	9.883	EPSD	ICGC	7.780	Down-regulation
AGC_Akt_AKT1_ST	Q2PPJ7	RALGAPA2	P31749	AKT1	S698	W699C	699	Missense	proximal	1	no	10.338	10.102	EPSD	ICGC;COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	Q2PPJ7	RALGAPA2	P31749	AKT1	S698	G692W	692	Missense	distal	-6	no	10.338	10.304	EPSD	ICGC;COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	Q2PPJ7	RALGAPA2	P31749	AKT1	S698	G692V	692	Missense	distal	-6	no	10.338	10.342	EPSD	ICGC;COSMIC	7.780	Up-regulation
AGC_Akt_AKT1_ST	Q2PPJ7	RALGAPA2	P31749	AKT1	S713	T706N	706	Missense	distal	-7	no	10.632	10.467	EPSD	ICGC;COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	Q2PPJ7	RALGAPA2	P31749	AKT1	S713	R712S	712	Missense	proximal	-1	no	10.632	10.621	EPSD	ICGC;COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	Q2PPJ7	RALGAPA2	P31749	AKT1	T715	R712S	712	Missense	distal	-3	no	14.221	6.444	PhosphoSitePlus;EPSD	ICGC;COSMIC	7.780	Loss
AGC_Akt_AKT1_ST	Q2PPJ7	RALGAPA2	P31749	AKT1	S717	R712S	712	Missense	distal	-5	no	10.425	5.955	EPSD	ICGC;COSMIC	7.780	Loss
AGC_Akt_AKT1_ST	Q2PPJ7	RALGAPA2	P31749	AKT1	S766	D769N	769	Missense	distal	3	no	11.428	11.484	EPSD	ICGC;COSMIC	7.780	Up-regulation
AGC_Akt_AKT1_ST	Q2PPJ7	RALGAPA2	P31749	AKT1	S766	T767N	767	Missense	proximal	1	no	11.428	11.146	EPSD	ICGC	7.780	Down-regulation
AGC_Akt_AKT1_ST	Q2PPJ7	RALGAPA2	P31749	AKT1	S768	D769N	769	Missense	proximal	1	no	8.956	9.080	EPSD	ICGC;COSMIC	7.780	Up-regulation
AGC_Akt_AKT1_ST	Q2PPJ7	RALGAPA2	P31749	AKT1	S768	T767N	767	Missense	proximal	-1	no	8.956	8.932	EPSD	ICGC	7.780	Down-regulation
AGC_Akt_AKT1_ST	Q2PPJ7	RALGAPA2	P31749	AKT1	S820	S820R	820	Missense	central	0	yes	9.942	0.000	EPSD	ICGC	7.780	Loss
AGC_Akt_AKT1_ST	Q2PPJ7	RALGAPA2	P31749	AKT1	S821	S820R	820	Missense	proximal	-1	no	11.519	11.529	EPSD	ICGC	7.780	Up-regulation
AGC_Akt_AKT1_ST	Q2PPJ7	RALGAPA2	P31749	AKT1	S1467	S1467P	1467	Missense	central	0	yes	9.698	0.000	EPSD	ICGC;COSMIC	7.780	Loss
AGC_Akt_AKT1_ST	Q2PPJ7	RALGAPA2	P31749	AKT1	S1493	S1497L	1497	Missense	distal	4	no	10.565	10.753	EPSD	ICGC;COSMIC	7.780	Up-regulation
AGC_Akt_AKT1_ST	Q2PPJ7	RALGAPA2	P31749	AKT1	S1493	H1500N	1500	Missense	distal	7	no	10.565	10.594	EPSD	ICGC	7.780	Up-regulation
AGC_Akt_AKT1_ST	Q2PPJ7	RALGAPA2	P31749	AKT1	S1493	P1487H	1487	Missense	distal	-6	no	10.565	10.544	EPSD	ICGC;COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	Q2PPJ7	RALGAPA2	P31749	AKT1	T1646	R1644H	1644	Missense	proximal	-2	no	8.788	7.927	EPSD	ICGC;COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	Q2PPJ7	RALGAPA2	P31749	AKT1	T1646	D1639V	1639	Missense	distal	-7	no	8.788	8.882	EPSD	ICGC	7.780	Up-regulation
AGC_Akt_AKT1_ST	Q2PPJ7	RALGAPA2	P31749	AKT1	T1646	A1650V	1650	Missense	distal	4	no	8.788	8.844	EPSD	ICGC;COSMIC	7.780	Up-regulation
AGC_Akt_AKT1_ST	Q2PPJ7	RALGAPA2	P31749	AKT1	T1646	K1648N	1648	Missense	proximal	2	no	8.788	8.503	EPSD	ICGC	7.780	Down-regulation
AGC_Akt_AKT1_ST	Q3V6T2	CCDC88A	P31749	AKT1	T15	Q12K	12	Missense	distal	-3	no	5.542	8.233	EPSD	ICGC;COSMIC	7.780	Gain
AGC_Akt_AKT1_ST	Q3V6T2	CCDC88A	P31749	AKT1	S245	L249P	249	Missense	distal	4	no	11.676	11.643	EPSD	ICGC	7.780	Down-regulation
AGC_Akt_AKT1_ST	Q3V6T2	CCDC88A	P31749	AKT1	S245	L249M	249	Missense	distal	4	no	11.676	11.651	EPSD	ICGC;COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	Q3V6T2	CCDC88A	P31749	AKT1	S245	S250W	250	Missense	distal	5	no	11.676	11.589	EPSD	ICGC;COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	Q3V6T2	CCDC88A	P31749	AKT1	S775	L782I	782	Missense	distal	7	no	8.329	8.298	EPSD	ICGC	7.780	Down-regulation
AGC_Akt_AKT1_ST	Q3V6T2	CCDC88A	P31749	AKT1	S913	Q920H	920	Missense	distal	7	no	8.703	8.687	EPSD	ICGC;COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	Q3V6T2	CCDC88A	P31749	AKT1	S913	K915R	915	Missense	proximal	2	no	8.703	8.515	EPSD	ICGC	7.780	Down-regulation
AGC_Akt_AKT1_ST	Q3V6T2	CCDC88A	P31749	AKT1	S913	T918N	918	Missense	distal	5	no	8.703	8.669	EPSD	ICGC;COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	Q3V6T2	CCDC88A	P31749	AKT1	S1462	S1461C	1461	Missense	proximal	-1	no	8.042	7.982	EPSD	ICGC	7.780	Down-regulation
AGC_Akt_AKT1_ST	Q3V6T2	CCDC88A	P31749	AKT1	S1796	S1790Y	1790	Missense	distal	-6	no	10.067	10.008	EPSD	ICGC;COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	P42345	MTOR	P31749	AKT1	T314	A321V	321	Missense	distal	7	no	11.505	11.501	EPSD	ICGC	7.780	Down-regulation
AGC_Akt_AKT1_ST	P42345	MTOR	P31749	AKT1	S1166	S1166R	1166	Missense	central	0	yes	8.003	0.000	EPSD	ICGC;COSMIC	7.780	Loss
AGC_Akt_AKT1_ST	P42345	MTOR	P31749	AKT1	S1166	A1173G	1173	Missense	distal	7	no	8.003	7.981	EPSD	ICGC;COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	P42345	MTOR	P31749	AKT1	S1166	V1160G	1160	Missense	distal	-6	no	8.003	7.999	EPSD	ICGC;COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	P42345	MTOR	P31749	AKT1	S1171	S1166R	1166	Missense	distal	-5	no	4.347	8.817	EPSD	ICGC;COSMIC	7.780	Gain
AGC_Akt_AKT1_ST	P42345	MTOR	P31749	AKT1	S1288	L1281M	1281	Missense	distal	-7	no	10.483	10.500	EPSD	ICGC;COSMIC	7.780	Up-regulation
AGC_Akt_AKT1_ST	P42345	MTOR	P31749	AKT1	S1288	L1284M	1284	Missense	distal	-4	no	10.483	10.697	EPSD	ICGC	7.780	Up-regulation
AGC_Akt_AKT1_ST	P42345	MTOR	P31749	AKT1	S1893	S1893F	1893	Missense	central	0	yes	12.435	0.000	EPSD	ICGC	7.780	Loss
AGC_Akt_AKT1_ST	P42345	MTOR	P31749	AKT1	S1893	R1890S	1890	Missense	distal	-3	no	12.435	4.659	EPSD	ICGC;COSMIC	7.780	Loss
AGC_Akt_AKT1_ST	P42345	MTOR	P31749	AKT1	T1948	P1951H	1951	Missense	distal	3	no	10.263	10.244	EPSD	ICGC	7.780	Down-regulation
AGC_Akt_AKT1_ST	P42345	MTOR	P31749	AKT1	T2173	L2174I	2174	Missense	proximal	1	no	15.593	15.245	EPSD	ICGC	7.780	Down-regulation
AGC_Akt_AKT1_ST	P42345	MTOR	P31749	AKT1	T2173	G2176D	2176	Missense	distal	3	no	15.593	15.572	EPSD	ICGC;COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	P42345	MTOR	P31749	AKT1	S2221	S2215T	2215	Missense	distal	-6	no	8.739	8.769	EPSD	ICGC;COSMIC	7.780	Up-regulation
AGC_Akt_AKT1_ST	P42345	MTOR	P31749	AKT1	S2221	Q2223L	2223	Missense	proximal	2	no	8.739	8.482	EPSD	ICGC;COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	P42345	MTOR	P31749	AKT1	T2444	R2445S	2445	Missense	proximal	1	no	12.611	12.466	EPSD	ICGC;COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	P42345	MTOR	P31749	AKT1	T2444	N2439S	2439	Missense	distal	-5	no	12.611	12.625	EPSD	ICGC;COSMIC	7.780	Up-regulation
AGC_Akt_AKT1_ST	P42345	MTOR	P31749	AKT1	T2446	R2445S	2445	Missense	proximal	-1	no	15.598	15.588	PhosphoSitePlus;EPSD	ICGC;COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	P42345	MTOR	P31749	AKT1	T2446	N2439S	2439	Missense	distal	-7	no	15.598	15.713	PhosphoSitePlus;EPSD	ICGC;COSMIC	7.780	Up-regulation
AGC_Akt_AKT1_ST	P42345	MTOR	P31749	AKT1	S2448	R2445S	2445	Missense	distal	-3	no	17.580	9.803	EPSD;PhosphoSitePlus	ICGC;COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	P42345	MTOR	P31749	AKT1	S2450	E2456K	2456	Missense	distal	6	no	11.759	11.829	EPSD	ICGC;COSMIC	7.780	Up-regulation
AGC_Akt_AKT1_ST	P42345	MTOR	P31749	AKT1	S2450	R2445S	2445	Missense	distal	-5	no	11.759	7.289	EPSD	ICGC;COSMIC	7.780	Loss
AGC_Akt_AKT1_ST	P42345	MTOR	P31749	AKT1	T2473	E2477Q	2477	Missense	distal	4	no	8.095	8.150	EPSD	ICGC;COSMIC	7.780	Up-regulation
AGC_Akt_AKT1_ST	P42345	MTOR	P31749	AKT1	T2473	P2466Q	2466	Missense	distal	-7	no	8.095	8.150	EPSD	ICGC;COSMIC	7.780	Up-regulation
AGC_Akt_AKT1_ST	P42345	MTOR	P31749	AKT1	T2473	A2467D	2467	Missense	distal	-6	no	8.095	8.031	EPSD	ICGC	7.780	Down-regulation
AGC_Akt_AKT1_ST	P42345	MTOR	P31749	AKT1	S2514	R2511Q	2511	Missense	distal	-3	no	10.472	3.261	EPSD	ICGC;COSMIC	7.780	Loss
AGC_Akt_AKT1_ST	P42345	MTOR	P31749	AKT1	S2514	G2510V	2510	Missense	distal	-4	no	10.472	10.107	EPSD	ICGC;COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	P42345	MTOR	P31749	AKT1	S2514	R2511L	2511	Missense	distal	-3	no	10.472	3.478	EPSD	ICGC;COSMIC	7.780	Loss
AGC_Akt_AKT1_ST	P42345	MTOR	P31749	AKT1	S2514	D2512G	2512	Missense	proximal	-2	no	10.472	11.171	EPSD	ICGC;COSMIC	7.780	Up-regulation
AGC_Akt_AKT1_ST	P35232	PHB	P31749	AKT1	T108	S101R	101	Missense	distal	-7	no	9.561	9.617	EPSD	ICGC;COSMIC	7.780	Up-regulation
AGC_Akt_AKT1_ST	P35232	PHB	P31749	AKT1	T108	R105H	105	Missense	distal	-3	no	9.561	4.863	EPSD	ICGC;COSMIC	7.780	Loss
AGC_Akt_AKT1_ST	P35232	PHB	P31749	AKT1	S151	S151N	151	Missense	central	0	yes	11.967	0.000	EPSD	ICGC;COSMIC	7.780	Loss
AGC_Akt_AKT1_ST	P35232	PHB	P31749	AKT1	S151	S151R	151	Missense	central	0	yes	11.967	0.000	EPSD	ICGC	7.780	Loss
AGC_Akt_AKT1_ST	P35232	PHB	P31749	AKT1	S151	D153E	153	Missense	proximal	2	no	11.967	12.377	EPSD	ICGC;COSMIC	7.780	Up-regulation
AGC_Akt_AKT1_ST	P35232	PHB	P31749	AKT1	T258	R255Q	255	Missense	distal	-3	no	16.968	9.757	PhosphoSitePlus	ICGC	7.780	Down-regulation
AGC_Akt_AKT1_ST	Q13045	FLII	P31749	AKT1	S90	G95R	95	Missense	distal	5	no	10.721	10.791	EPSD	ICGC;COSMIC	7.780	Up-regulation
AGC_Akt_AKT1_ST	Q13045	FLII	P31749	AKT1	S90	A88D	88	Missense	proximal	-2	no	10.721	9.779	EPSD	ICGC	7.780	Down-regulation
AGC_Akt_AKT1_ST	Q13045	FLII	P31749	AKT1	S436	R431K	431	Missense	distal	-5	no	16.954	14.557	PhosphoSitePlus	ICGC;COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	Q13045	FLII	P31749	AKT1	S436	D439G	439	Missense	distal	3	no	16.954	16.975	PhosphoSitePlus	ICGC	7.780	Up-regulation
AGC_Akt_AKT1_ST	Q13045	FLII	P31749	AKT1	T665	T669M	669	Missense	distal	4	no	8.822	8.991	EPSD	ICGC;COSMIC	7.780	Up-regulation
AGC_Akt_AKT1_ST	Q13045	FLII	P31749	AKT1	T665	A672V	672	Missense	distal	7	no	8.822	8.818	EPSD	ICGC;COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	Q13045	FLII	P31749	AKT1	T818	A817V	817	Missense	proximal	-1	no	14.407	14.393	EPSD	ICGC;COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	Q13045	FLII	P31749	AKT1	T818	V819A	819	Missense	proximal	1	no	14.407	14.335	EPSD	ICGC	7.780	Down-regulation
AGC_Akt_AKT1_ST	Q13045	FLII	P31749	AKT1	S822	V819A	819	Missense	distal	-3	no	7.666	8.229	EPSD	ICGC	7.780	Gain
AGC_Akt_AKT1_ST	Q13045	FLII	P31749	AKT1	T826	V819A	819	Missense	distal	-7	no	9.376	9.504	EPSD	ICGC	7.780	Up-regulation
AGC_Akt_AKT1_ST	Q9UGI0	ZRANB1	P31749	AKT1	S78	V76A	76	Missense	proximal	-2	no	15.915	16.653	PhosphoSitePlus;EPSD	ICGC;COSMIC	7.780	Up-regulation
AGC_Akt_AKT1_ST	Q9UGI0	ZRANB1	P31749	AKT1	S78	V76L	76	Missense	proximal	-2	no	15.915	16.248	PhosphoSitePlus;EPSD	ICGC	7.780	Up-regulation
AGC_Akt_AKT1_ST	Q9UGI0	ZRANB1	P31749	AKT1	S78	S71I	71	Missense	distal	-7	no	15.915	15.543	PhosphoSitePlus;EPSD	ICGC	7.780	Down-regulation
AGC_Akt_AKT1_ST	Q9UGI0	ZRANB1	P31749	AKT1	S78	R75S	75	Missense	distal	-3	no	15.915	8.138	PhosphoSitePlus;EPSD	ICGC;COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	Q9UGI0	ZRANB1	P31749	AKT1	S115	P120H	120	Missense	distal	5	no	11.781	11.768	EPSD	ICGC;COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	Q9UGI0	ZRANB1	P31749	AKT1	T117	P120H	120	Missense	distal	3	no	17.579	17.560	EPSD;PhosphoSitePlus	ICGC;COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	Q9UGI0	ZRANB1	P31749	AKT1	S119	P120H	120	Missense	proximal	1	no	12.143	12.120	EPSD	ICGC;COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	Q9UGI0	ZRANB1	P31749	AKT1	T694	R691W	691	Missense	distal	-3	no	11.373	2.433	EPSD	ICGC;COSMIC	7.780	Loss
AGC_Akt_AKT1_ST	Q13043	STK4	P31749	AKT1	S21	E28K	28	Missense	distal	7	no	7.766	7.800	EPSD	ICGC	7.780	Gain
AGC_Akt_AKT1_ST	Q13043	STK4	P31749	AKT1	S21	L17S	17	Missense	distal	-4	no	7.766	8.890	EPSD	ICGC;COSMIC	7.780	Gain
AGC_Akt_AKT1_ST	Q13043	STK4	P31749	AKT1	T120	T122A	122	Missense	proximal	2	no	13.999	13.698	EPSD;PhosphoSitePlus	ICGC;COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	Q13043	STK4	P31749	AKT1	T122	T122A	122	Missense	central	0	yes	11.495	0.000	EPSD	ICGC;COSMIC	7.780	Loss
AGC_Akt_AKT1_ST	Q13043	STK4	P31749	AKT1	S307	Q309E	309	Missense	proximal	2	no	11.863	11.963	EPSD	ICGC;COSMIC	7.780	Up-regulation
AGC_Akt_AKT1_ST	Q13043	STK4	P31749	AKT1	T387	K382N	382	Missense	distal	-5	no	12.521	10.433	EPSD;PhosphoSitePlus	ICGC;COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	Q99683	MAP3K5	P31749	AKT1	S115	S110R	110	Missense	distal	-5	no	5.495	9.966	EPSD	ICGC	7.780	Gain
AGC_Akt_AKT1_ST	Q99683	MAP3K5	P31749	AKT1	S613	E618D	618	Missense	distal	5	no	10.419	10.377	EPSD	ICGC;COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	Q99683	MAP3K5	P31749	AKT1	S615	E618D	618	Missense	distal	3	no	9.337	9.267	EPSD	ICGC;COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	Q99683	MAP3K5	P31749	AKT1	S719	S716R	716	Missense	distal	-3	no	5.588	13.364	EPSD	ICGC	7.780	Gain
AGC_Akt_AKT1_ST	O43464	HTRA2	P31749	AKT1	S13	R18Q	18	Missense	distal	5	no	10.311	10.260	EPSD	ICGC;COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	O43464	HTRA2	P31749	AKT1	S13	R15P	15	Missense	proximal	2	no	10.311	10.147	EPSD	ICGC;COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	O43464	HTRA2	P31749	AKT1	S41	S41L	41	Missense	central	0	yes	9.709	0.000	EPSD	ICGC;COSMIC	7.780	Loss
AGC_Akt_AKT1_ST	O43464	HTRA2	P31749	AKT1	S41	G42R	42	Missense	proximal	1	no	9.709	10.159	EPSD	ICGC	7.780	Up-regulation
AGC_Akt_AKT1_ST	O43464	HTRA2	P31749	AKT1	S96	E97D	97	Missense	proximal	1	no	17.614	17.497	EPSD	ICGC	7.780	Down-regulation
AGC_Akt_AKT1_ST	Q9UN36	NDRG2	P31749	AKT1	T330	R329C	329	Missense	proximal	-1	no	10.623	10.552	EPSD	ICGC	7.780	Down-regulation
AGC_Akt_AKT1_ST	Q9UN36	NDRG2	P31749	AKT1	S332	R329C	329	Missense	distal	-3	no	15.948	9.774	EPSD;PhosphoSitePlus	ICGC	7.780	Down-regulation
AGC_Akt_AKT1_ST	Q9UN36	NDRG2	P31749	AKT1	T334	R329C	329	Missense	distal	-5	no	9.795	5.719	EPSD	ICGC	7.780	Loss
AGC_Akt_AKT1_ST	Q9UN36	NDRG2	P31749	AKT1	S346	S346L	346	Missense	central	0	yes	13.688	0.000	EPSD	ICGC;COSMIC	7.780	Loss
AGC_Akt_AKT1_ST	Q9UN36	NDRG2	P31749	AKT1	S346	S344C	344	Missense	proximal	-2	no	13.688	12.035	EPSD	ICGC	7.780	Down-regulation
AGC_Akt_AKT1_ST	Q9UN36	NDRG2	P31749	AKT1	T348	S346L	346	Missense	proximal	-2	no	15.892	15.035	PhosphoSitePlus;EPSD	ICGC;COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	Q9UN36	NDRG2	P31749	AKT1	T348	S344C	344	Missense	distal	-4	no	15.892	14.299	PhosphoSitePlus;EPSD	ICGC	7.780	Down-regulation
AGC_Akt_AKT1_ST	Q9UN36	NDRG2	P31749	AKT1	S350	S346L	346	Missense	distal	-4	no	19.104	17.980	EPSD	ICGC;COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	Q9UN36	NDRG2	P31749	AKT1	S350	S344C	344	Missense	distal	-6	no	19.104	18.958	EPSD	ICGC	7.780	Down-regulation
AGC_Akt_AKT1_ST	Q9UN36	NDRG2	P31749	AKT1	S352	S346L	346	Missense	distal	-6	no	11.781	11.731	EPSD	ICGC;COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	O95999	BCL10	P31749	AKT1	S7	E2K	2	Missense	distal	-5	no	6.575	8.272	EPSD	ICGC;COSMIC	7.780	Gain
AGC_Akt_AKT1_ST	O95999	BCL10	P31749	AKT1	T52	R58Q	58	Missense	distal	6	no	11.782	11.711	EPSD	ICGC;COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	O95999	BCL10	P31749	AKT1	S138	N132S	132	Missense	distal	-6	no	14.006	14.053	EPSD	ICGC;COSMIC	7.780	Up-regulation
AGC_Akt_AKT1_ST	O95999	BCL10	P31749	AKT1	S138	S134F	134	Missense	distal	-4	no	14.006	12.838	EPSD	ICGC	7.780	Down-regulation
AGC_Akt_AKT1_ST	O95999	BCL10	P31749	AKT1	S218	G213E	213	Missense	distal	-5	no	9.371	9.341	PhosphoSitePlus;EPSD	ICGC;COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	O95999	BCL10	P31749	AKT1	S218	P224L	224	Missense	distal	6	no	9.371	9.361	PhosphoSitePlus;EPSD	ICGC;GDSC;CCLE	7.780	Down-regulation
AGC_Akt_AKT1_ST	O95999	BCL10	P31749	AKT1	S227	P224L	224	Missense	distal	-3	no	7.837	7.483	EPSD	ICGC;GDSC;CCLE	7.780	Loss
AGC_Akt_AKT1_ST	O95999	BCL10	P31749	AKT1	T229	P224L	224	Missense	distal	-5	no	12.071	11.955	EPSD	ICGC;GDSC;CCLE	7.780	Down-regulation
AGC_Akt_AKT1_ST	O95999	BCL10	P31749	AKT1	S231	P224L	224	Missense	distal	-7	no	18.236	18.196	EPSD;PhosphoSitePlus	ICGC;GDSC;CCLE	7.780	Down-regulation
AGC_Akt_AKT1_ST	P35240	NF2	P31749	AKT1	S13	L14R	14	Missense	proximal	1	no	9.220	9.266	EPSD	ICGC;COSMIC	7.780	Up-regulation
AGC_Akt_AKT1_ST	P35240	NF2	P31749	AKT1	S13	S10I	10	Missense	distal	-3	no	9.220	9.916	EPSD	ICGC;COSMIC	7.780	Up-regulation
AGC_Akt_AKT1_ST	P35240	NF2	P31749	AKT1	S13	R8S	8	Missense	distal	-5	no	9.220	4.750	EPSD	ICGC;COSMIC	7.780	Loss
AGC_Akt_AKT1_ST	P35240	NF2	P31749	AKT1	T230	L234I	234	Missense	distal	4	no	10.354	10.427	EPSD;PhosphoSitePlus	ICGC;COSMIC	7.780	Up-regulation
AGC_Akt_AKT1_ST	P35240	NF2	P31749	AKT1	S265	W258C	258	Missense	distal	-7	no	9.943	9.887	EPSD	ICGC	7.780	Down-regulation
AGC_Akt_AKT1_ST	Q92547	TOPBP1	P31749	AKT1	S142	H145N	145	Missense	distal	3	no	8.324	8.368	EPSD	ICGC	7.780	Up-regulation
AGC_Akt_AKT1_ST	Q92547	TOPBP1	P31749	AKT1	T185	Q180K	180	Missense	distal	-5	no	7.886	9.717	EPSD	ICGC;COSMIC	7.780	Up-regulation
AGC_Akt_AKT1_ST	Q92547	TOPBP1	P31749	AKT1	T185	T188N	188	Missense	distal	3	no	7.886	7.831	EPSD	ICGC;COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	Q92547	TOPBP1	P31749	AKT1	T292	E285K	285	Missense	distal	-7	no	8.427	8.620	EPSD	ICGC;COSMIC	7.780	Up-regulation
AGC_Akt_AKT1_ST	Q92547	TOPBP1	P31749	AKT1	T292	P286H	286	Missense	distal	-6	no	8.427	8.407	EPSD	ICGC;COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	Q92547	TOPBP1	P31749	AKT1	T292	P299H	299	Missense	distal	7	no	8.427	8.422	EPSD	ICGC	7.780	Down-regulation
AGC_Akt_AKT1_ST	Q92547	TOPBP1	P31749	AKT1	S471	S471N	471	Missense	central	0	yes	9.143	0.000	EPSD	ICGC;COSMIC	7.780	Loss
AGC_Akt_AKT1_ST	Q92547	TOPBP1	P31749	AKT1	T779	R785S	785	Missense	distal	6	no	8.056	8.058	EPSD	ICGC	7.780	Up-regulation
AGC_Akt_AKT1_ST	Q92547	TOPBP1	P31749	AKT1	S788	R785S	785	Missense	distal	-3	no	10.424	2.647	EPSD	ICGC	7.780	Loss
AGC_Akt_AKT1_ST	Q92547	TOPBP1	P31749	AKT1	S805	Q810K	810	Missense	distal	5	no	9.379	9.423	EPSD	ICGC	7.780	Up-regulation
AGC_Akt_AKT1_ST	Q92547	TOPBP1	P31749	AKT1	S805	A803T	803	Missense	proximal	-2	no	9.379	9.764	EPSD	ICGC;COSMIC;GDSC	7.780	Up-regulation
AGC_Akt_AKT1_ST	Q92547	TOPBP1	P31749	AKT1	S860	S860N	860	Missense	central	0	yes	12.893	0.000	EPSD	ICGC	7.780	Loss
AGC_Akt_AKT1_ST	Q92547	TOPBP1	P31749	AKT1	S860	I867M	867	Missense	distal	7	no	12.893	12.932	EPSD	ICGC;COSMIC	7.780	Up-regulation
AGC_Akt_AKT1_ST	Q92547	TOPBP1	P31749	AKT1	S1016	R1013G	1013	Missense	distal	-3	no	11.081	4.325	EPSD	ICGC;COSMIC	7.780	Loss
AGC_Akt_AKT1_ST	Q92547	TOPBP1	P31749	AKT1	S1159	A1158D	1158	Missense	proximal	-1	no	15.377	15.350	PhosphoSitePlus	ICGC	7.780	Down-regulation
AGC_Akt_AKT1_ST	Q92547	TOPBP1	P31749	AKT1	S1159	C1166S	1166	Missense	distal	7	no	15.377	15.500	PhosphoSitePlus	ICGC	7.780	Up-regulation
AGC_Akt_AKT1_ST	Q92547	TOPBP1	P31749	AKT1	S1216	S1216Y	1216	Missense	central	0	yes	8.218	0.000	EPSD	ICGC;COSMIC	7.780	Loss
AGC_Akt_AKT1_ST	Q92547	TOPBP1	P31749	AKT1	T1256	T1260A	1260	Missense	distal	4	no	10.715	10.844	EPSD	ICGC;COSMIC	7.780	Up-regulation
AGC_Akt_AKT1_ST	Q92547	TOPBP1	P31749	AKT1	T1256	H1249Q	1249	Missense	distal	-7	no	10.715	10.822	EPSD	ICGC	7.780	Up-regulation
AGC_Akt_AKT1_ST	Q92547	TOPBP1	P31749	AKT1	T1256	T1256M	1256	Missense	central	0	yes	10.715	0.000	EPSD	ICGC;GDSC;CCLE	7.780	Loss
AGC_Akt_AKT1_ST	Q15672	TWIST1	P31749	AKT1	S42	G35R	35	Missense	distal	-7	no	18.341	18.583	EPSD;PhosphoSitePlus	ICGC;COSMIC	7.780	Up-regulation
AGC_Akt_AKT1_ST	Q15672	TWIST1	P31749	AKT1	S42	R37H	37	Missense	distal	-5	no	18.341	15.246	EPSD;PhosphoSitePlus	ICGC	7.780	Down-regulation
AGC_Akt_AKT1_ST	Q15672	TWIST1	P31749	AKT1	T121	Q119L	119	Missense	proximal	-2	no	14.091	13.936	PhosphoSitePlus;EPSD	ICGC	7.780	Down-regulation
AGC_Akt_AKT1_ST	Q15672	TWIST1	P31749	AKT1	T121	R116L	116	Missense	distal	-5	no	14.091	9.965	PhosphoSitePlus;EPSD	ICGC;COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	Q15672	TWIST1	P31749	AKT1	S123	Q119L	119	Missense	distal	-4	no	16.369	15.781	EPSD;PhosphoSitePlus	ICGC	7.780	Down-regulation
AGC_Akt_AKT1_ST	Q15672	TWIST1	P31749	AKT1	S123	A130T	130	Missense	distal	7	no	16.369	16.430	EPSD;PhosphoSitePlus	ICGC;COSMIC	7.780	Up-regulation
AGC_Akt_AKT1_ST	Q15672	TWIST1	P31749	AKT1	S123	R116L	116	Missense	distal	-7	no	16.369	16.080	EPSD;PhosphoSitePlus	ICGC;COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	P00533	EGFR	P31749	AKT1	S645	K642E	642	Missense	distal	-3	no	7.881	5.830	EPSD	ICGC;COSMIC	7.780	Loss
AGC_Akt_AKT1_ST	P00533	EGFR	P31749	AKT1	S991	R986Q	986	Missense	distal	-5	no	10.653	6.425	EPSD	ICGC;COSMIC	7.780	Loss
AGC_Akt_AKT1_ST	P00533	EGFR	P31749	AKT1	S991	S991R	991	Missense	central	0	yes	10.653	0.000	EPSD	ICGC;COSMIC	7.780	Loss
AGC_Akt_AKT1_ST	P00533	EGFR	P31749	AKT1	S991	L989I	989	Missense	proximal	-2	no	10.653	10.268	EPSD	ICGC;COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	P00533	EGFR	P31749	AKT1	S1190	Y1197C	1197	Missense	distal	7	no	7.988	7.908	EPSD	ICGC;COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	P00533	EGFR	P31749	AKT1	S1204	Y1197C	1197	Missense	distal	-7	no	11.475	11.258	EPSD	ICGC;COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	P00533	EGFR	P31749	AKT1	S1204	L1198I	1198	Missense	distal	-6	no	11.475	11.405	EPSD	ICGC;COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	Q8TDN4	CABLES1	P31749	AKT1	S257	L263M	263	Missense	distal	6	no	12.099	12.103	EPSD	ICGC;COSMIC	7.780	Up-regulation
AGC_Akt_AKT1_ST	Q8TDN4	CABLES1	P31749	AKT1	T374	G369R	369	Missense	distal	-5	no	9.611	13.676	EPSD	ICGC	7.780	Up-regulation
AGC_Akt_AKT1_ST	Q8TDN4	CABLES1	P31749	AKT1	T415	R412W	412	Missense	distal	-3	no	9.748	0.807	PhosphoSitePlus;EPSD	ICGC;COSMIC	7.780	Loss
AGC_Akt_AKT1_ST	Q8TDN4	CABLES1	P31749	AKT1	S418	R412W	412	Missense	distal	-6	no	8.321	8.174	EPSD	ICGC;COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	Q8TDN4	CABLES1	P31749	AKT1	S434	R437W	437	Missense	distal	3	no	12.832	12.720	EPSD	ICGC	7.780	Down-regulation
AGC_Akt_AKT1_ST	P38936	CDKN1A	P31749	AKT1	T145	R143L	143	Missense	proximal	-2	no	17.056	16.387	EPSD;PhosphoSitePlus	ICGC	7.780	Down-regulation
AGC_Akt_AKT1_ST	P38936	CDKN1A	P31749	AKT1	T145	R142Q	142	Missense	distal	-3	no	17.056	9.844	EPSD;PhosphoSitePlus	ICGC	7.780	Down-regulation
AGC_Akt_AKT1_ST	P38936	CDKN1A	P31749	AKT1	T145	R140Q	140	Missense	distal	-5	no	17.056	12.828	EPSD;PhosphoSitePlus	ICGC;COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	P38936	CDKN1A	P31749	AKT1	S146	R143L	143	Missense	distal	-3	no	16.217	9.223	PhosphoSitePlus;EPSD	ICGC	7.780	Down-regulation
AGC_Akt_AKT1_ST	P38936	CDKN1A	P31749	AKT1	S146	R142Q	142	Missense	distal	-4	no	16.217	15.596	PhosphoSitePlus;EPSD	ICGC	7.780	Down-regulation
AGC_Akt_AKT1_ST	P38936	CDKN1A	P31749	AKT1	S146	R140Q	140	Missense	distal	-6	no	16.217	16.133	PhosphoSitePlus;EPSD	ICGC;COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	P38936	CDKN1A	P31749	AKT1	S160	K163N	163	Missense	distal	3	no	10.380	10.322	EPSD	ICGC	7.780	Down-regulation
AGC_Akt_AKT1_ST	O75030	MITF	P31749	AKT1	S405	L404F	404	Missense	proximal	-1	no	10.170	10.164	EPSD	ICGC	7.780	Down-regulation
AGC_Akt_AKT1_ST	O75030	MITF	P31749	AKT1	S405	R400Q	400	Missense	distal	-5	no	10.170	5.943	EPSD	ICGC;COSMIC	7.780	Loss
AGC_Akt_AKT1_ST	O75030	MITF	P31749	AKT1	T510	G506R	506	Missense	distal	-4	no	7.224	8.039	EPSD	ICGC;COSMIC	7.780	Gain
AGC_Akt_AKT1_ST	O75030	MITF	P31749	AKT1	S511	G506R	506	Missense	distal	-5	no	7.238	11.303	EPSD	ICGC;COSMIC	7.780	Gain
AGC_Akt_AKT1_ST	O75030	MITF	P31749	AKT1	S512	G506R	506	Missense	distal	-6	no	11.955	12.068	EPSD	ICGC;COSMIC	7.780	Up-regulation
AGC_Akt_AKT1_ST	O75030	MITF	P31749	AKT1	S512	M519T	519	Missense	distal	7	no	11.955	12.024	EPSD	ICGC	7.780	Up-regulation
AGC_Akt_AKT1_ST	O75030	MITF	P31749	AKT1	S512	R513Q	513	Missense	proximal	1	no	11.955	11.660	EPSD	ICGC;COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	O75030	MITF	P31749	AKT1	S515	M519T	519	Missense	distal	4	no	8.872	8.704	EPSD	ICGC	7.780	Down-regulation
AGC_Akt_AKT1_ST	O75030	MITF	P31749	AKT1	S515	R513Q	513	Missense	proximal	-2	no	8.872	8.360	EPSD	ICGC;COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	O75030	MITF	P31749	AKT1	S516	E523K	523	Missense	distal	7	no	15.700	15.734	PhosphoSitePlus	ICGC;COSMIC	7.780	Up-regulation
AGC_Akt_AKT1_ST	O75030	MITF	P31749	AKT1	S516	M519T	519	Missense	distal	3	no	15.700	15.784	PhosphoSitePlus	ICGC	7.780	Up-regulation
AGC_Akt_AKT1_ST	O75030	MITF	P31749	AKT1	S516	R513Q	513	Missense	distal	-3	no	15.700	8.489	PhosphoSitePlus	ICGC;COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	O75030	MITF	P31749	AKT1	S518	E523K	523	Missense	distal	5	no	11.452	11.486	EPSD	ICGC;COSMIC	7.780	Up-regulation
AGC_Akt_AKT1_ST	O75030	MITF	P31749	AKT1	S518	M519T	519	Missense	proximal	1	no	11.452	11.708	EPSD	ICGC	7.780	Up-regulation
AGC_Akt_AKT1_ST	O75030	MITF	P31749	AKT1	S518	R513Q	513	Missense	distal	-5	no	11.452	7.224	EPSD	ICGC;COSMIC	7.780	Loss
AGC_Akt_AKT1_ST	P51617	IRAK1	P31749	AKT1	T512	L518I	518	Missense	distal	6	no	10.258	10.197	EPSD	ICGC;COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	O75376	NCOR1	P31749	AKT1	S24	R19C	19	Missense	distal	-5	no	8.966	4.889	EPSD	ICGC;COSMIC	7.780	Loss
AGC_Akt_AKT1_ST	O75376	NCOR1	P31749	AKT1	S24	Y20S	20	Missense	distal	-4	no	8.966	9.826	EPSD	ICGC;COSMIC	7.780	Up-regulation
AGC_Akt_AKT1_ST	O75376	NCOR1	P31749	AKT1	S24	Q26K	26	Missense	proximal	2	no	8.966	9.272	EPSD	ICGC;COSMIC	7.780	Up-regulation
AGC_Akt_AKT1_ST	O75376	NCOR1	P31749	AKT1	S24	P21H	21	Missense	distal	-3	no	8.966	10.907	EPSD	ICGC;COSMIC	7.780	Up-regulation
AGC_Akt_AKT1_ST	O75376	NCOR1	P31749	AKT1	S24	P30S	30	Missense	distal	6	no	8.966	9.059	EPSD	ICGC	7.780	Up-regulation
AGC_Akt_AKT1_ST	O75376	NCOR1	P31749	AKT1	S24	P22S	22	Missense	proximal	-2	no	8.966	9.790	EPSD	ICGC	7.780	Up-regulation
AGC_Akt_AKT1_ST	O75376	NCOR1	P31749	AKT1	S24	P22H	22	Missense	proximal	-2	no	8.966	8.741	EPSD	ICGC;COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	O75376	NCOR1	P31749	AKT1	S70	P77Q	77	Missense	distal	7	no	11.234	11.244	EPSD	ICGC	7.780	Up-regulation
AGC_Akt_AKT1_ST	O75376	NCOR1	P31749	AKT1	S70	P69S	69	Missense	proximal	-1	no	11.234	11.263	EPSD	ICGC	7.780	Up-regulation
AGC_Akt_AKT1_ST	O75376	NCOR1	P31749	AKT1	S70	P69F	69	Missense	proximal	-1	no	11.234	11.228	EPSD	ICGC	7.780	Down-regulation
AGC_Akt_AKT1_ST	O75376	NCOR1	P31749	AKT1	S70	P77T	77	Missense	distal	7	no	11.234	11.302	EPSD	ICGC;COSMIC	7.780	Up-regulation
AGC_Akt_AKT1_ST	O75376	NCOR1	P31749	AKT1	S88	P91T	91	Missense	distal	3	no	11.655	11.736	EPSD	ICGC;COSMIC	7.780	Up-regulation
AGC_Akt_AKT1_ST	O75376	NCOR1	P31749	AKT1	S401	R398W	398	Missense	distal	-3	no	11.034	2.093	EPSD	ICGC;COSMIC;CCLE	7.780	Loss
AGC_Akt_AKT1_ST	O75376	NCOR1	P31749	AKT1	S401	M406I	406	Missense	distal	5	no	11.034	10.994	EPSD	ICGC;COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	O75376	NCOR1	P31749	AKT1	S401	Q396K	396	Missense	distal	-5	no	11.034	12.864	EPSD	ICGC	7.780	Up-regulation
AGC_Akt_AKT1_ST	O75376	NCOR1	P31749	AKT1	T586	M589K	589	Missense	distal	3	no	9.066	9.154	EPSD	ICGC;COSMIC	7.780	Up-regulation
AGC_Akt_AKT1_ST	O75376	NCOR1	P31749	AKT1	T590	A594S	594	Missense	distal	4	no	12.112	11.987	EPSD	ICGC;COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	O75376	NCOR1	P31749	AKT1	T590	A594T	594	Missense	distal	4	no	12.112	11.982	EPSD	ICGC;COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	O75376	NCOR1	P31749	AKT1	T590	M589K	589	Missense	proximal	-1	no	12.112	12.147	EPSD	ICGC;COSMIC	7.780	Up-regulation
AGC_Akt_AKT1_ST	O75376	NCOR1	P31749	AKT1	S1234	I1241M	1241	Missense	distal	7	no	9.438	9.477	EPSD	ICGC	7.780	Up-regulation
AGC_Akt_AKT1_ST	O75376	NCOR1	P31749	AKT1	T1522	S1528C	1528	Missense	distal	6	no	8.608	8.405	EPSD	ICGC;COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	O75376	NCOR1	P31749	AKT1	S1636	Q1640K	1640	Missense	distal	4	no	11.783	11.626	EPSD	ICGC	7.780	Down-regulation
AGC_Akt_AKT1_ST	O75376	NCOR1	P31749	AKT1	S1750	R1755W	1755	Missense	distal	5	no	11.999	11.905	EPSD	ICGC	7.780	Down-regulation
AGC_Akt_AKT1_ST	O75376	NCOR1	P31749	AKT1	S1758	R1755W	1755	Missense	distal	-3	no	11.618	2.677	EPSD	ICGC	7.780	Loss
AGC_Akt_AKT1_ST	O75376	NCOR1	P31749	AKT1	S1760	R1755W	1755	Missense	distal	-5	no	9.917	4.397	EPSD	ICGC	7.780	Loss
AGC_Akt_AKT1_ST	O75376	NCOR1	P31749	AKT1	S2184	E2177K	2177	Missense	distal	-7	no	9.265	9.457	EPSD	ICGC;COSMIC	7.780	Up-regulation
AGC_Akt_AKT1_ST	O75376	NCOR1	P31749	AKT1	S2184	E2177D	2177	Missense	distal	-7	no	9.265	9.043	EPSD	ICGC;COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	P12755	SKI	P31749	AKT1	T103	E108D	108	Missense	distal	5	no	9.827	9.785	EPSD	ICGC	7.780	Down-regulation
AGC_Akt_AKT1_ST	P12755	SKI	P31749	AKT1	S325	R320L	320	Missense	distal	-5	no	8.452	4.325	EPSD	ICGC	7.780	Loss
AGC_Akt_AKT1_ST	P12755	SKI	P31749	AKT1	S326	R320L	320	Missense	distal	-6	no	10.792	10.707	EPSD	ICGC	7.780	Down-regulation
AGC_Akt_AKT1_ST	P12755	SKI	P31749	AKT1	S383	E390K	390	Missense	distal	7	no	10.698	10.732	EPSD	ICGC;COSMIC	7.780	Up-regulation
AGC_Akt_AKT1_ST	P12755	SKI	P31749	AKT1	T458	R453L	453	Missense	distal	-5	no	16.405	12.279	PhosphoSitePlus	ICGC;COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	P12755	SKI	P31749	AKT1	S498	S495F	495	Missense	distal	-3	no	6.362	8.544	EPSD	ICGC;COSMIC	7.780	Gain
AGC_Akt_AKT1_ST	P05106	ITGB3	P31749	AKT1	T441	V445M	445	Missense	distal	4	no	9.003	8.986	EPSD	ICGC;COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	P05106	ITGB3	P31749	AKT1	T779	R786L	786	Missense	distal	7	no	8.504	8.430	PhosphoSitePlus	ICGC	7.780	Down-regulation
AGC_Akt_AKT1_ST	Q9BXL7	CARD11	P31749	AKT1	S116	G123S	123	Missense	distal	7	no	12.134	12.208	EPSD	ICGC;COSMIC	7.780	Up-regulation
AGC_Akt_AKT1_ST	Q9BXL7	CARD11	P31749	AKT1	S116	I118V	118	Missense	proximal	2	no	12.134	12.253	EPSD	ICGC;COSMIC	7.780	Up-regulation
AGC_Akt_AKT1_ST	Q9BXL7	CARD11	P31749	AKT1	S116	S116A	116	Missense	central	0	yes	12.134	0.000	EPSD	ICGC;COSMIC	7.780	Loss
AGC_Akt_AKT1_ST	Q9BXL7	CARD11	P31749	AKT1	S116	P111S	111	Missense	distal	-5	no	12.134	11.674	EPSD	ICGC;COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	Q9BXL7	CARD11	P31749	AKT1	S116	F115I	115	Missense	proximal	-1	no	12.134	12.120	EPSD	ICGC;COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	Q9BXL7	CARD11	P31749	AKT1	T117	G123S	123	Missense	distal	6	no	10.169	10.274	EPSD	ICGC;COSMIC	7.780	Up-regulation
AGC_Akt_AKT1_ST	Q9BXL7	CARD11	P31749	AKT1	T117	I118V	118	Missense	proximal	1	no	10.169	10.416	EPSD	ICGC;COSMIC	7.780	Up-regulation
AGC_Akt_AKT1_ST	Q9BXL7	CARD11	P31749	AKT1	T117	S116A	116	Missense	proximal	-1	no	10.169	10.148	EPSD	ICGC;COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	Q9BXL7	CARD11	P31749	AKT1	T117	P111S	111	Missense	distal	-6	no	10.169	10.233	EPSD	ICGC;COSMIC	7.780	Up-regulation
AGC_Akt_AKT1_ST	Q9BXL7	CARD11	P31749	AKT1	T117	F115I	115	Missense	proximal	-2	no	10.169	9.794	EPSD	ICGC;COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	Q9BXL7	CARD11	P31749	AKT1	S212	A218E	218	Missense	distal	6	no	9.759	9.782	EPSD	ICGC;COSMIC	7.780	Up-regulation
AGC_Akt_AKT1_ST	Q9BXL7	CARD11	P31749	AKT1	S212	K215Q	215	Missense	distal	3	no	9.759	9.684	EPSD	ICGC;COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	Q9BXL7	CARD11	P31749	AKT1	S212	A218V	218	Missense	distal	6	no	9.759	9.727	EPSD	ICGC;CCLE	7.780	Down-regulation
AGC_Akt_AKT1_ST	Q9BXL7	CARD11	P31749	AKT1	S439	S439A	439	Missense	central	0	yes	12.607	0.000	EPSD	ICGC;COSMIC	7.780	Loss
AGC_Akt_AKT1_ST	Q9BXL7	CARD11	P31749	AKT1	S439	S433G	433	Missense	distal	-6	no	12.607	12.527	EPSD	ICGC;COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	Q9BXL7	CARD11	P31749	AKT1	S439	D446E	446	Missense	distal	7	no	12.607	12.650	EPSD	ICGC	7.780	Up-regulation
AGC_Akt_AKT1_ST	Q9BXL7	CARD11	P31749	AKT1	S439	D441E	441	Missense	proximal	2	no	12.607	13.017	EPSD	ICGC;COSMIC	7.780	Up-regulation
AGC_Akt_AKT1_ST	Q9BXL7	CARD11	P31749	AKT1	S439	D446N	446	Missense	distal	7	no	12.607	12.648	EPSD	ICGC	7.780	Up-regulation
AGC_Akt_AKT1_ST	Q9BXL7	CARD11	P31749	AKT1	S442	S439A	439	Missense	distal	-3	no	8.450	9.924	EPSD	ICGC;COSMIC	7.780	Up-regulation
AGC_Akt_AKT1_ST	Q9BXL7	CARD11	P31749	AKT1	S442	L449M	449	Missense	distal	7	no	8.450	8.458	EPSD	ICGC;COSMIC	7.780	Up-regulation
AGC_Akt_AKT1_ST	Q9BXL7	CARD11	P31749	AKT1	S442	D446E	446	Missense	distal	4	no	8.450	8.304	EPSD	ICGC	7.780	Down-regulation
AGC_Akt_AKT1_ST	Q9BXL7	CARD11	P31749	AKT1	S442	D441E	441	Missense	proximal	-1	no	8.450	8.484	EPSD	ICGC;COSMIC	7.780	Up-regulation
AGC_Akt_AKT1_ST	Q9BXL7	CARD11	P31749	AKT1	S442	D446N	446	Missense	distal	4	no	8.450	8.335	EPSD	ICGC	7.780	Down-regulation
AGC_Akt_AKT1_ST	Q9BXL7	CARD11	P31749	AKT1	S512	S512P	512	Missense	central	0	yes	11.042	0.000	EPSD	ICGC;COSMIC	7.780	Loss
AGC_Akt_AKT1_ST	Q9BXL7	CARD11	P31749	AKT1	S512	T519K	519	Missense	distal	7	no	11.042	11.032	EPSD	ICGC	7.780	Down-regulation
AGC_Akt_AKT1_ST	Q9BXL7	CARD11	P31749	AKT1	S512	Q508H	508	Missense	distal	-4	no	11.042	10.604	EPSD	ICGC;COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	Q9BXL7	CARD11	P31749	AKT1	S558	A565S	565	Missense	distal	7	no	11.722	11.772	EPSD;PhosphoSitePlus	ICGC;COSMIC	7.780	Up-regulation
AGC_Akt_AKT1_ST	Q9BXL7	CARD11	P31749	AKT1	S558	Q552K	552	Missense	distal	-6	no	11.722	11.792	EPSD;PhosphoSitePlus	ICGC	7.780	Up-regulation
AGC_Akt_AKT1_ST	Q9BXL7	CARD11	P31749	AKT1	S558	P553L	553	Missense	distal	-5	no	11.722	11.606	EPSD;PhosphoSitePlus	ICGC	7.780	Down-regulation
AGC_Akt_AKT1_ST	Q9BXL7	CARD11	P31749	AKT1	S562	A565S	565	Missense	distal	3	no	7.778	7.836	EPSD	ICGC;COSMIC	7.780	Gain
AGC_Akt_AKT1_ST	Q9BXL7	CARD11	P31749	AKT1	S644	N637K	637	Missense	distal	-7	no	12.029	12.186	EPSD;PhosphoSitePlus	ICGC	7.780	Up-regulation
AGC_Akt_AKT1_ST	Q9BXL7	CARD11	P31749	AKT1	S644	R650W	650	Missense	distal	6	no	12.029	11.871	EPSD;PhosphoSitePlus	ICGC;COSMIC;GDSC;CCLE	7.780	Down-regulation
AGC_Akt_AKT1_ST	Q9BXL7	CARD11	P31749	AKT1	S652	V659M	659	Missense	distal	7	no	10.482	10.478	PhosphoSitePlus;EPSD	ICGC;COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	Q9BXL7	CARD11	P31749	AKT1	S652	R650W	650	Missense	proximal	-2	no	10.482	9.227	PhosphoSitePlus;EPSD	ICGC;COSMIC;GDSC;CCLE	7.780	Down-regulation
AGC_Akt_AKT1_ST	Q9BXL7	CARD11	P31749	AKT1	S655	V659M	659	Missense	distal	4	no	7.875	7.858	EPSD	ICGC;COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	Q9BXL7	CARD11	P31749	AKT1	S655	R650W	650	Missense	distal	-5	no	7.875	2.355	EPSD	ICGC;COSMIC;GDSC;CCLE	7.780	Loss
AGC_Akt_AKT1_ST	Q9BXL7	CARD11	P31749	AKT1	T871	R869W	869	Missense	proximal	-2	no	8.814	7.560	EPSD	ICGC;COSMIC	7.780	Loss
AGC_Akt_AKT1_ST	Q9BXL7	CARD11	P31749	AKT1	T871	T871N	871	Missense	central	0	yes	8.814	0.000	EPSD	ICGC	7.780	Loss
AGC_Akt_AKT1_ST	Q9BXL7	CARD11	P31749	AKT1	T871	E876K	876	Missense	distal	5	no	8.814	8.848	EPSD	ICGC;COSMIC	7.780	Up-regulation
AGC_Akt_AKT1_ST	Q9BXL7	CARD11	P31749	AKT1	T871	A877E	877	Missense	distal	6	no	8.814	8.837	EPSD	ICGC;COSMIC	7.780	Up-regulation
AGC_Akt_AKT1_ST	Q9BXL7	CARD11	P31749	AKT1	S923	E917V	917	Missense	distal	-6	no	14.521	14.491	EPSD	ICGC;COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	Q9BXL7	CARD11	P31749	AKT1	S964	S959R	959	Missense	distal	-5	no	3.552	8.022	EPSD	ICGC	7.780	Gain
AGC_Akt_AKT1_ST	Q9BXL7	CARD11	P31749	AKT1	T1020	R1027L	1027	Missense	distal	7	no	11.802	11.728	EPSD	ICGC	7.780	Down-regulation
AGC_Akt_AKT1_ST	Q9BXL7	CARD11	P31749	AKT1	T1020	S1026Y	1026	Missense	distal	6	no	11.802	11.713	EPSD	ICGC;COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	P98177	FOXO4	P31749	AKT1	S30	R29L	29	Missense	proximal	-1	no	11.302	11.263	EPSD	ICGC	7.780	Down-regulation
AGC_Akt_AKT1_ST	P98177	FOXO4	P31749	AKT1	T32	R29L	29	Missense	distal	-3	no	15.576	8.582	EPSD;PhosphoSitePlus	ICGC	7.780	Down-regulation
AGC_Akt_AKT1_ST	P98177	FOXO4	P31749	AKT1	S197	A195T	195	Missense	proximal	-2	no	15.494	15.880	EPSD;PhosphoSitePlus	ICGC;COSMIC	7.780	Up-regulation
AGC_Akt_AKT1_ST	Q96S44	TP53RK	P31749	AKT1	S34	G35D	35	Missense	proximal	1	no	11.604	11.696	EPSD	ICGC;COSMIC	7.780	Up-regulation
AGC_Akt_AKT1_ST	P08727	KRT19	P31749	AKT1	S10	R7C	7	Missense	distal	-3	no	13.670	7.496	EPSD	ICGC;COSMIC	7.780	Loss
AGC_Akt_AKT1_ST	P08727	KRT19	P31749	AKT1	S10	R7G	7	Missense	distal	-3	no	13.670	6.914	EPSD	ICGC	7.780	Loss
AGC_Akt_AKT1_ST	P08727	KRT19	P31749	AKT1	S10	S5I	5	Missense	distal	-5	no	13.670	13.573	EPSD	ICGC;COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	P08727	KRT19	P31749	AKT1	T12	R7C	7	Missense	distal	-5	no	10.134	6.058	EPSD	ICGC;COSMIC	7.780	Loss
AGC_Akt_AKT1_ST	P08727	KRT19	P31749	AKT1	T12	R7G	7	Missense	distal	-5	no	10.134	6.070	EPSD	ICGC	7.780	Loss
AGC_Akt_AKT1_ST	P08727	KRT19	P31749	AKT1	T12	S5I	5	Missense	distal	-7	no	10.134	9.762	EPSD	ICGC;COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	P08727	KRT19	P31749	AKT1	S14	R7C	7	Missense	distal	-7	no	8.082	7.603	EPSD	ICGC;COSMIC	7.780	Loss
AGC_Akt_AKT1_ST	P08727	KRT19	P31749	AKT1	S14	R7G	7	Missense	distal	-7	no	8.082	7.840	EPSD	ICGC	7.780	Down-regulation
AGC_Akt_AKT1_ST	P08727	KRT19	P31749	AKT1	S46	S48F	48	Missense	proximal	2	no	13.656	13.078	EPSD	ICGC;COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	P08727	KRT19	P31749	AKT1	S46	R51H	51	Missense	distal	5	no	13.656	13.582	EPSD	ICGC;COSMIC;CCLE	7.780	Down-regulation
AGC_Akt_AKT1_ST	P08727	KRT19	P31749	AKT1	S46	R51C	51	Missense	distal	5	no	13.656	13.530	EPSD	ICGC	7.780	Down-regulation
AGC_Akt_AKT1_ST	P08727	KRT19	P31749	AKT1	S46	V45I	45	Missense	proximal	-1	no	13.656	13.641	EPSD	ICGC;COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	P08727	KRT19	P31749	AKT1	S48	S48F	48	Missense	central	0	yes	11.675	0.000	EPSD	ICGC;COSMIC	7.780	Loss
AGC_Akt_AKT1_ST	P08727	KRT19	P31749	AKT1	S48	R51H	51	Missense	distal	3	no	11.675	11.591	EPSD	ICGC;COSMIC;CCLE	7.780	Down-regulation
AGC_Akt_AKT1_ST	P08727	KRT19	P31749	AKT1	S48	R51C	51	Missense	distal	3	no	11.675	11.514	EPSD	ICGC	7.780	Down-regulation
AGC_Akt_AKT1_ST	P08727	KRT19	P31749	AKT1	S48	V45I	45	Missense	distal	-3	no	11.675	11.459	EPSD	ICGC;COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	P08727	KRT19	P31749	AKT1	S48	S54F	54	Missense	distal	6	no	11.675	11.555	EPSD	ICGC;COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	P08727	KRT19	P31749	AKT1	S54	S48F	48	Missense	distal	-6	no	10.731	10.656	EPSD	ICGC;COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	P08727	KRT19	P31749	AKT1	S54	A60G	60	Missense	distal	6	no	10.731	10.708	EPSD	ICGC;COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	P08727	KRT19	P31749	AKT1	S54	R51H	51	Missense	distal	-3	no	10.731	6.032	EPSD	ICGC;COSMIC;CCLE	7.780	Loss
AGC_Akt_AKT1_ST	P08727	KRT19	P31749	AKT1	S54	R51C	51	Missense	distal	-3	no	10.731	4.558	EPSD	ICGC	7.780	Loss
AGC_Akt_AKT1_ST	P08727	KRT19	P31749	AKT1	S54	S54F	54	Missense	central	0	yes	10.731	0.000	EPSD	ICGC;COSMIC	7.780	Loss
AGC_Akt_AKT1_ST	P08727	KRT19	P31749	AKT1	S56	A60G	60	Missense	distal	4	no	8.833	8.883	EPSD	ICGC;COSMIC	7.780	Up-regulation
AGC_Akt_AKT1_ST	P08727	KRT19	P31749	AKT1	S56	R51H	51	Missense	distal	-5	no	8.833	5.738	EPSD	ICGC;COSMIC;CCLE	7.780	Loss
AGC_Akt_AKT1_ST	P08727	KRT19	P31749	AKT1	S56	R51C	51	Missense	distal	-5	no	8.833	4.756	EPSD	ICGC	7.780	Loss
AGC_Akt_AKT1_ST	P08727	KRT19	P31749	AKT1	S56	S54F	54	Missense	proximal	-2	no	8.833	7.967	EPSD	ICGC;COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	P08727	KRT19	P31749	AKT1	S93	R90C	90	Missense	distal	-3	no	9.315	3.141	EPSD	ICGC;COSMIC	7.780	Loss
AGC_Akt_AKT1_ST	P08727	KRT19	P31749	AKT1	S93	R90H	90	Missense	distal	-3	no	9.315	4.616	EPSD	ICGC;COSMIC	7.780	Loss
AGC_Akt_AKT1_ST	P08727	KRT19	P31749	AKT1	S93	A100V	100	Missense	distal	7	no	9.315	9.310	EPSD	ICGC	7.780	Down-regulation
AGC_Akt_AKT1_ST	P08727	KRT19	P31749	AKT1	S128	Y127S	127	Missense	proximal	-1	no	10.090	10.115	EPSD	ICGC;COSMIC	7.780	Up-regulation
AGC_Akt_AKT1_ST	P08727	KRT19	P31749	AKT1	S128	Y127H	127	Missense	proximal	-1	no	10.090	10.081	EPSD	ICGC;COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	P08727	KRT19	P31749	AKT1	S128	D126A	126	Missense	proximal	-2	no	10.090	11.031	EPSD	ICGC;COSMIC	7.780	Up-regulation
AGC_Akt_AKT1_ST	P63104	YWHAZ	P31749	AKT1	S58	A54P	54	Missense	distal	-4	no	11.487	11.473	PhosphoSitePlus	ICGC;COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	P63104	YWHAZ	P31749	AKT1	T88	I93N	93	Missense	distal	5	no	9.570	9.632	EPSD	ICGC;COSMIC	7.780	Up-regulation
AGC_Akt_AKT1_ST	P63104	YWHAZ	P31749	AKT1	T88	K85N	85	Missense	distal	-3	no	9.570	6.613	EPSD	ICGC;COSMIC	7.780	Loss
AGC_Akt_AKT1_ST	Q9Y3M2	CBY1	P31749	AKT1	S20	A19S	19	Missense	proximal	-1	no	10.579	10.600	PhosphoSitePlus	ICGC	7.780	Up-regulation
AGC_Akt_AKT1_ST	Q9Y3M2	CBY1	P31749	AKT1	S22	A19S	19	Missense	distal	-3	no	8.719	7.245	EPSD	ICGC	7.780	Loss
AGC_Akt_AKT1_ST	Q9Y3M2	CBY1	P31749	AKT1	T44	G41R	41	Missense	distal	-3	no	3.602	10.358	EPSD	ICGC;COSMIC	7.780	Gain
AGC_Akt_AKT1_ST	P98170	XIAP	P31749	AKT1	T32	N35D	35	Missense	distal	3	no	10.213	10.158	EPSD	ICGC;COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	P98170	XIAP	P31749	AKT1	T32	S38C	38	Missense	distal	6	no	10.213	10.011	EPSD	ICGC	7.780	Down-regulation
AGC_Akt_AKT1_ST	P98170	XIAP	P31749	AKT1	T32	L30F	30	Missense	proximal	-2	no	10.213	10.203	EPSD	ICGC;COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	P98170	XIAP	P31749	AKT1	S87	C90Y	90	Missense	distal	3	no	15.077	15.186	PhosphoSitePlus	ICGC;COSMIC	7.780	Up-regulation
AGC_Akt_AKT1_ST	P98170	XIAP	P31749	AKT1	S218	P212T	212	Missense	distal	-6	no	9.119	9.214	EPSD	ICGC;COSMIC	7.780	Up-regulation
AGC_Akt_AKT1_ST	P98170	XIAP	P31749	AKT1	S218	R222Q	222	Missense	distal	4	no	9.119	9.242	EPSD	ICGC;COSMIC	7.780	Up-regulation
AGC_Akt_AKT1_ST	P98170	XIAP	P31749	AKT1	S218	R215L	215	Missense	distal	-3	no	9.119	2.125	EPSD	ICGC;COSMIC	7.780	Loss
AGC_Akt_AKT1_ST	P98170	XIAP	P31749	AKT1	S261	R268Q	268	Missense	distal	7	no	12.601	12.546	EPSD	ICGC;COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	P98170	XIAP	P31749	AKT1	T363	I370T	370	Missense	distal	7	no	8.331	8.439	EPSD	ICGC;COSMIC	7.780	Up-regulation
AGC_Akt_AKT1_ST	Q92879	CELF1	P31749	AKT1	S28	P24S	24	Missense	distal	-4	no	12.783	13.519	PhosphoSitePlus	ICGC;COSMIC	7.780	Up-regulation
AGC_Akt_AKT1_ST	Q92879	CELF1	P31749	AKT1	S28	L35P	35	Missense	distal	7	no	12.783	12.791	PhosphoSitePlus	ICGC;COSMIC	7.780	Up-regulation
AGC_Akt_AKT1_ST	Q92879	CELF1	P31749	AKT1	S28	E29Q	29	Missense	proximal	1	no	12.783	12.729	PhosphoSitePlus	ICGC;COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	Q92879	CELF1	P31749	AKT1	S28	R25M	25	Missense	distal	-3	no	12.783	5.277	PhosphoSitePlus	ICGC;COSMIC	7.780	Loss
AGC_Akt_AKT1_ST	P08047	SP1	P31749	AKT1	S42	S36L	36	Missense	distal	-6	no	11.770	11.719	EPSD;PhosphoSitePlus	ICGC;COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	P08047	SP1	P31749	AKT1	S42	S46C	46	Missense	distal	4	no	11.770	12.114	EPSD;PhosphoSitePlus	ICGC;COSMIC	7.780	Up-regulation
AGC_Akt_AKT1_ST	P08047	SP1	P31749	AKT1	S42	F35L	35	Missense	distal	-7	no	11.770	11.814	EPSD;PhosphoSitePlus	ICGC;COSMIC	7.780	Up-regulation
AGC_Akt_AKT1_ST	P08047	SP1	P31749	AKT1	S670	R669L	669	Missense	proximal	-1	no	9.797	9.758	EPSD	ICGC	7.780	Down-regulation
AGC_Akt_AKT1_ST	P49841	GSK3B	P31749	AKT1	T7	A11S	11	Missense	distal	4	no	11.492	11.367	EPSD	ICGC;COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	P49841	GSK3B	P31749	AKT1	S9	A11S	11	Missense	proximal	2	no	17.010	17.385	PhosphoSitePlus	ICGC;COSMIC	7.780	Up-regulation
AGC_Akt_AKT1_ST	P49841	GSK3B	P31749	AKT1	S13	A11S	11	Missense	proximal	-2	no	7.992	8.444	EPSD	ICGC;COSMIC	7.780	Up-regulation
AGC_Akt_AKT1_ST	P49841	GSK3B	P31749	AKT1	S35	D33E	33	Missense	proximal	-2	no	10.668	11.653	EPSD	ICGC	7.780	Up-regulation
AGC_Akt_AKT1_ST	P49841	GSK3B	P31749	AKT1	S55	D49E	49	Missense	distal	-6	no	8.668	8.741	EPSD	ICGC	7.780	Up-regulation
AGC_Akt_AKT1_ST	P49841	GSK3B	P31749	AKT1	S55	Q52K	52	Missense	distal	-3	no	8.668	11.359	EPSD	ICGC	7.780	Up-regulation
AGC_Akt_AKT1_ST	P49841	GSK3B	P31749	AKT1	S55	E53K	53	Missense	proximal	-2	no	8.668	9.327	EPSD	ICGC;COSMIC	7.780	Up-regulation
AGC_Akt_AKT1_ST	P49841	GSK3B	P31749	AKT1	S147	P154H	154	Missense	distal	7	no	10.133	10.127	EPSD	ICGC;COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	P49841	GSK3B	P31749	AKT1	S147	A149D	149	Missense	proximal	2	no	10.133	9.910	EPSD	ICGC	7.780	Down-regulation
AGC_Akt_AKT1_ST	P49841	GSK3B	P31749	AKT1	S147	T152R	152	Missense	distal	5	no	10.133	10.140	EPSD	ICGC;COSMIC	7.780	Up-regulation
AGC_Akt_AKT1_ST	P49841	GSK3B	P31749	AKT1	S147	Q151R	151	Missense	distal	4	no	10.133	10.010	EPSD	ICGC;COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	P49841	GSK3B	P31749	AKT1	T408	G406R	406	Missense	proximal	-2	no	12.001	12.507	EPSD	ICGC;COSMIC	7.780	Up-regulation
AGC_Akt_AKT1_ST	P49841	GSK3B	P31749	AKT1	T408	S415T	415	Missense	distal	7	no	12.001	12.011	EPSD	ICGC;COSMIC	7.780	Up-regulation
AGC_Akt_AKT1_ST	P49841	GSK3B	P31749	AKT1	S417	S415T	415	Missense	proximal	-2	no	8.563	8.496	EPSD	ICGC;COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	P23396	RPS3	P31749	AKT1	T70	A71D	71	Missense	proximal	1	no	14.505	14.365	PhosphoSitePlus	ICGC;COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	Q53EL6	PDCD4	P31749	AKT1	S67	R69L	69	Missense	proximal	2	no	15.873	15.499	PhosphoSitePlus;EPSD	ICGC	7.780	Down-regulation
AGC_Akt_AKT1_ST	Q53EL6	PDCD4	P31749	AKT1	S67	G72V	72	Missense	distal	5	no	15.873	15.876	PhosphoSitePlus;EPSD	ICGC	7.780	Up-regulation
AGC_Akt_AKT1_ST	Q53EL6	PDCD4	P31749	AKT1	S68	R69L	69	Missense	proximal	1	no	8.819	8.773	EPSD	ICGC	7.780	Down-regulation
AGC_Akt_AKT1_ST	Q53EL6	PDCD4	P31749	AKT1	S68	G72V	72	Missense	distal	4	no	8.819	8.825	EPSD	ICGC	7.780	Up-regulation
AGC_Akt_AKT1_ST	Q53EL6	PDCD4	P31749	AKT1	S76	S82I	82	Missense	distal	6	no	11.265	11.101	EPSD	ICGC	7.780	Down-regulation
AGC_Akt_AKT1_ST	Q53EL6	PDCD4	P31749	AKT1	S76	S76L	76	Missense	central	0	yes	11.265	0.000	EPSD	ICGC;COSMIC	7.780	Loss
AGC_Akt_AKT1_ST	Q53EL6	PDCD4	P31749	AKT1	S76	R69L	69	Missense	distal	-7	no	11.265	10.976	EPSD	ICGC	7.780	Down-regulation
AGC_Akt_AKT1_ST	Q53EL6	PDCD4	P31749	AKT1	S76	G72V	72	Missense	distal	-4	no	11.265	10.900	EPSD	ICGC	7.780	Down-regulation
AGC_Akt_AKT1_ST	Q53EL6	PDCD4	P31749	AKT1	S78	S82I	82	Missense	distal	4	no	8.800	9.061	EPSD	ICGC	7.780	Up-regulation
AGC_Akt_AKT1_ST	Q53EL6	PDCD4	P31749	AKT1	S78	S76L	76	Missense	proximal	-2	no	8.800	7.943	EPSD	ICGC;COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	Q53EL6	PDCD4	P31749	AKT1	S78	G72V	72	Missense	distal	-6	no	8.800	8.804	EPSD	ICGC	7.780	Up-regulation
AGC_Akt_AKT1_ST	Q53EL6	PDCD4	P31749	AKT1	S224	C227F	227	Missense	distal	3	no	7.759	7.838	EPSD	ICGC	7.780	Gain
AGC_Akt_AKT1_ST	Q53EL6	PDCD4	P31749	AKT1	S313	W315C	315	Missense	proximal	2	no	13.372	13.175	EPSD	ICGC;COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	Q53EL6	PDCD4	P31749	AKT1	S313	G318V	318	Missense	distal	5	no	13.372	13.376	EPSD	ICGC;COSMIC	7.780	Up-regulation
AGC_Akt_AKT1_ST	Q53EL6	PDCD4	P31749	AKT1	S457	G451V	451	Missense	distal	-6	no	19.966	19.970	EPSD;PhosphoSitePlus	ICGC	7.780	Up-regulation
AGC_Akt_AKT1_ST	Q53EL6	PDCD4	P31749	AKT1	S457	E458G	458	Missense	proximal	1	no	19.966	19.757	EPSD;PhosphoSitePlus	ICGC;COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	P61247	RPS3A	P31749	AKT1	T10	N6K	6	Missense	distal	-4	no	10.266	10.905	EPSD;PhosphoSitePlus	ICGC;COSMIC	7.780	Up-regulation
AGC_Akt_AKT1_ST	P61247	RPS3A	P31749	AKT1	T10	A17V	17	Missense	distal	7	no	10.266	10.262	EPSD;PhosphoSitePlus	ICGC;COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	P61247	RPS3A	P31749	AKT1	S112	R107S	107	Missense	distal	-5	no	8.961	4.491	PhosphoSitePlus;EPSD	ICGC;COSMIC	7.780	Loss
AGC_Akt_AKT1_ST	P61247	RPS3A	P31749	AKT1	S154	R151L	151	Missense	distal	-3	no	11.269	4.275	EPSD	ICGC;COSMIC	7.780	Loss
AGC_Akt_AKT1_ST	Q9H6Z4	RANBP3	P31749	AKT1	S221	E226D	226	Missense	distal	5	no	11.061	11.019	EPSD	ICGC;COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	P49918	CDKN1C	P31749	AKT1	S282	A283V	283	Missense	proximal	1	no	13.113	13.185	EPSD;PhosphoSitePlus	ICGC	7.780	Up-regulation
AGC_Akt_AKT1_ST	P49918	CDKN1C	P31749	AKT1	S282	E285D	285	Missense	distal	3	no	13.113	13.042	EPSD;PhosphoSitePlus	ICGC	7.780	Down-regulation
AGC_Akt_AKT1_ST	P49918	CDKN1C	P31749	AKT1	S282	K280N	280	Missense	proximal	-2	no	13.113	12.177	EPSD;PhosphoSitePlus	ICGC;COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	Q9BVI0	PHF20	P31749	AKT1	S157	R163L	163	Missense	distal	6	no	8.595	8.493	EPSD	ICGC;COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	Q9BVI0	PHF20	P31749	AKT1	S232	G233E	233	Missense	proximal	1	no	9.424	9.633	EPSD	ICGC;COSMIC	7.780	Up-regulation
AGC_Akt_AKT1_ST	Q9BVI0	PHF20	P31749	AKT1	S265	V271A	271	Missense	distal	6	no	15.666	15.697	PhosphoSitePlus;EPSD	ICGC;COSMIC	7.780	Up-regulation
AGC_Akt_AKT1_ST	Q9BVI0	PHF20	P31749	AKT1	S265	R260Q	260	Missense	distal	-5	no	15.666	11.438	PhosphoSitePlus;EPSD	ICGC	7.780	Down-regulation
AGC_Akt_AKT1_ST	Q9BVI0	PHF20	P31749	AKT1	S291	S291L	291	Missense	central	0	yes	15.793	0.000	EPSD;PhosphoSitePlus	ICGC	7.780	Loss
AGC_Akt_AKT1_ST	Q9BVI0	PHF20	P31749	AKT1	S328	R325M	325	Missense	distal	-3	no	12.591	5.085	EPSD	ICGC;COSMIC	7.780	Loss
AGC_Akt_AKT1_ST	Q9BVI0	PHF20	P31749	AKT1	S329	R325M	325	Missense	distal	-4	no	10.877	9.882	EPSD	ICGC;COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	Q9BVI0	PHF20	P31749	AKT1	S332	R325M	325	Missense	distal	-7	no	9.521	9.249	EPSD	ICGC;COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	Q9BVI0	PHF20	P31749	AKT1	S500	P499S	499	Missense	proximal	-1	no	10.263	10.292	EPSD	ICGC	7.780	Up-regulation
AGC_Akt_AKT1_ST	Q9BVI0	PHF20	P31749	AKT1	S502	P499S	499	Missense	distal	-3	no	8.563	7.427	EPSD	ICGC	7.780	Loss
AGC_Akt_AKT1_ST	Q9BVI0	PHF20	P31749	AKT1	S518	V515D	515	Missense	distal	-3	no	6.881	7.795	EPSD	ICGC;COSMIC	7.780	Gain
AGC_Akt_AKT1_ST	Q9BVI0	PHF20	P31749	AKT1	S896	P903Q	903	Missense	distal	7	no	11.270	11.280	EPSD	ICGC;COSMIC	7.780	Up-regulation
AGC_Akt_AKT1_ST	Q9BVI0	PHF20	P31749	AKT1	S902	P903Q	903	Missense	proximal	1	no	8.320	8.325	EPSD	ICGC;COSMIC	7.780	Up-regulation
AGC_Akt_AKT1_ST	P35226	BMI1	P31749	AKT1	S315	S321L	321	Missense	distal	6	no	8.854	8.750	EPSD	ICGC;COSMIC;CCLE	7.780	Down-regulation
AGC_Akt_AKT1_ST	P35226	BMI1	P31749	AKT1	S315	G319V	319	Missense	distal	4	no	8.854	8.860	EPSD	ICGC;COSMIC	7.780	Up-regulation
AGC_Akt_AKT1_ST	P35226	BMI1	P31749	AKT1	S315	R313Q	313	Missense	proximal	-2	no	8.854	8.341	EPSD	ICGC;COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	P35226	BMI1	P31749	AKT1	S316	S321L	321	Missense	distal	5	no	19.382	19.316	PhosphoSitePlus	ICGC;COSMIC;CCLE	7.780	Down-regulation
AGC_Akt_AKT1_ST	P35226	BMI1	P31749	AKT1	S316	G319V	319	Missense	distal	3	no	19.382	19.383	PhosphoSitePlus	ICGC;COSMIC	7.780	Up-regulation
AGC_Akt_AKT1_ST	P35226	BMI1	P31749	AKT1	S316	R313Q	313	Missense	distal	-3	no	19.382	12.171	PhosphoSitePlus	ICGC;COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	Q15910	EZH2	P31749	AKT1	T345	P350S	350	Missense	distal	5	no	10.433	10.486	EPSD	ICGC;COSMIC	7.780	Up-regulation
AGC_Akt_AKT1_ST	Q15910	EZH2	P31749	AKT1	T345	R342P	342	Missense	distal	-3	no	10.433	3.793	EPSD	ICGC;COSMIC	7.780	Loss
AGC_Akt_AKT1_ST	Q15910	EZH2	P31749	AKT1	T345	R349H	349	Missense	distal	4	no	10.433	10.618	EPSD	ICGC;COSMIC	7.780	Up-regulation
AGC_Akt_AKT1_ST	Q15910	EZH2	P31749	AKT1	S362	S362N	362	Missense	central	0	yes	8.380	0.000	EPSD	ICGC;COSMIC	7.780	Loss
AGC_Akt_AKT1_ST	Q15910	EZH2	P31749	AKT1	S362	R357W	357	Missense	distal	-5	no	8.380	2.860	EPSD	ICGC;COSMIC	7.780	Loss
AGC_Akt_AKT1_ST	Q15910	EZH2	P31749	AKT1	T367	S362N	362	Missense	distal	-5	no	10.054	10.039	EPSD	ICGC;COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	Q15910	EZH2	P31749	AKT1	T416	P417S	417	Missense	proximal	1	no	8.747	8.902	EPSD	ICGC;COSMIC	7.780	Up-regulation
AGC_Akt_AKT1_ST	Q15910	EZH2	P31749	AKT1	S647	C642R	642	Missense	distal	-5	no	5.050	9.127	EPSD	ICGC;COSMIC	7.780	Gain
AGC_Akt_AKT1_ST	Q15910	EZH2	P31749	AKT1	S690	R685H	685	Missense	distal	-5	no	8.977	5.882	EPSD	ICGC;COSMIC	7.780	Loss
AGC_Akt_AKT1_ST	Q15910	EZH2	P31749	AKT1	S690	S690L	690	Missense	central	0	yes	8.977	0.000	EPSD	ICGC;COSMIC	7.780	Loss
AGC_Akt_AKT1_ST	Q15910	EZH2	P31749	AKT1	S690	N688K	688	Missense	proximal	-2	no	8.977	9.914	EPSD	ICGC;COSMIC	7.780	Up-regulation
AGC_Akt_AKT1_ST	Q15910	EZH2	P31749	AKT1	S690	A697E	697	Missense	distal	7	no	8.977	8.994	EPSD	ICGC	7.780	Up-regulation
AGC_Akt_AKT1_ST	Q15910	EZH2	P31749	AKT1	S690	I684S	684	Missense	distal	-6	no	8.977	9.097	EPSD	ICGC;COSMIC	7.780	Up-regulation
AGC_Akt_AKT1_ST	Q15910	EZH2	P31749	AKT1	S690	R685G	685	Missense	distal	-5	no	8.977	4.913	EPSD	ICGC;COSMIC	7.780	Loss
AGC_Akt_AKT1_ST	Q15910	EZH2	P31749	AKT1	S690	K683E	683	Missense	distal	-7	no	8.977	8.784	EPSD	ICGC	7.780	Down-regulation
AGC_Akt_AKT1_ST	Q15910	EZH2	P31749	AKT1	S690	K683T	683	Missense	distal	-7	no	8.977	8.985	EPSD	ICGC	7.780	Up-regulation
AGC_Akt_AKT1_ST	Q15910	EZH2	P31749	AKT1	S690	A687V	687	Missense	distal	-3	no	8.977	8.415	EPSD	ICGC;COSMIC;CCLE	7.780	Down-regulation
AGC_Akt_AKT1_ST	Q96BF3	TMIGD2	P31749	AKT1	S220	S220R	220	Missense	central	0	yes	12.161	0.000	PhosphoSitePlus	ICGC	7.780	Loss
AGC_Akt_AKT1_ST	Q96BF3	TMIGD2	P31749	AKT1	S223	S220R	220	Missense	distal	-3	no	3.673	11.449	EPSD	ICGC	7.780	Gain
AGC_Akt_AKT1_ST	Q96BF3	TMIGD2	P31749	AKT1	S225	S220R	220	Missense	distal	-5	no	4.466	8.936	EPSD	ICGC	7.780	Gain
AGC_Akt_AKT1_ST	P49760	CLK2	P31749	AKT1	S9	R12Q	12	Missense	distal	3	no	13.250	13.194	EPSD	ICGC	7.780	Down-regulation
AGC_Akt_AKT1_ST	P49760	CLK2	P31749	AKT1	S10	R12Q	12	Missense	proximal	2	no	9.218	9.101	EPSD	ICGC	7.780	Down-regulation
AGC_Akt_AKT1_ST	P49760	CLK2	P31749	AKT1	S17	E20Q	20	Missense	distal	3	no	8.588	8.556	EPSD	ICGC;COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	P49760	CLK2	P31749	AKT1	S17	R12Q	12	Missense	distal	-5	no	8.588	4.360	EPSD	ICGC	7.780	Loss
AGC_Akt_AKT1_ST	P49760	CLK2	P31749	AKT1	S17	Y22C	22	Missense	distal	5	no	8.588	8.512	EPSD	ICGC;COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	P49760	CLK2	P31749	AKT1	S34	R31I	31	Missense	distal	-3	no	16.698	9.617	PhosphoSitePlus;EPSD	ICGC;COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	P49760	CLK2	P31749	AKT1	S36	R31I	31	Missense	distal	-5	no	17.235	12.667	EPSD	ICGC;COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	P49760	CLK2	P31749	AKT1	S50	R56Q	56	Missense	distal	6	no	15.690	15.619	EPSD	ICGC;COSMIC;GDSC	7.780	Down-regulation
AGC_Akt_AKT1_ST	P49760	CLK2	P31749	AKT1	S57	R62G	62	Missense	distal	5	no	11.612	11.541	EPSD	ICGC;COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	P49760	CLK2	P31749	AKT1	S57	R56Q	56	Missense	proximal	-1	no	11.612	11.580	EPSD	ICGC;COSMIC;GDSC	7.780	Down-regulation
AGC_Akt_AKT1_ST	P49760	CLK2	P31749	AKT1	S106	R103W	103	Missense	distal	-3	no	11.851	2.910	EPSD	ICGC;COSMIC	7.780	Loss
AGC_Akt_AKT1_ST	P49760	CLK2	P31749	AKT1	T127	S133L	133	Missense	distal	6	no	15.979	15.875	EPSD;PhosphoSitePlus	ICGC;COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	P49760	CLK2	P31749	AKT1	S133	S133L	133	Missense	central	0	yes	13.315	0.000	EPSD	ICGC;COSMIC	7.780	Loss
AGC_Akt_AKT1_ST	P49760	CLK2	P31749	AKT1	S133	R138K	138	Missense	distal	5	no	13.315	13.309	EPSD	ICGC	7.780	Down-regulation
AGC_Akt_AKT1_ST	P49760	CLK2	P31749	AKT1	S142	R138K	138	Missense	distal	-4	no	11.120	11.107	EPSD	ICGC	7.780	Down-regulation
AGC_Akt_AKT1_ST	P10275	AR	P31749	AKT1	S16	A22S	22	Missense	distal	6	no	12.059	12.141	EPSD	ICGC	7.780	Up-regulation
AGC_Akt_AKT1_ST	P10275	AR	P31749	AKT1	S16	V10G	10	Missense	distal	-6	no	12.059	12.055	EPSD	ICGC;COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	P10275	AR	P31749	AKT1	S16	P12T	12	Missense	distal	-4	no	12.059	12.851	EPSD	ICGC;COSMIC	7.780	Up-regulation
AGC_Akt_AKT1_ST	P10275	AR	P31749	AKT1	T18	A22S	22	Missense	distal	4	no	9.744	9.619	EPSD	ICGC	7.780	Down-regulation
AGC_Akt_AKT1_ST	P10275	AR	P31749	AKT1	T18	P12T	12	Missense	distal	-6	no	9.744	9.838	EPSD	ICGC;COSMIC	7.780	Up-regulation
AGC_Akt_AKT1_ST	P10275	AR	P31749	AKT1	S215	P218S	218	Missense	distal	3	no	14.508	14.589	EPSD;PhosphoSitePlus	ICGC	7.780	Up-regulation
AGC_Akt_AKT1_ST	P10275	AR	P31749	AKT1	S215	P218L	218	Missense	distal	3	no	14.508	14.492	EPSD;PhosphoSitePlus	ICGC	7.780	Down-regulation
AGC_Akt_AKT1_ST	P10275	AR	P31749	AKT1	S792	C785F	785	Missense	distal	-7	no	14.676	14.821	PhosphoSitePlus;EPSD	ICGC	7.780	Up-regulation
AGC_Akt_AKT1_ST	P10275	AR	P31749	AKT1	S792	R789S	789	Missense	distal	-3	no	14.676	6.900	PhosphoSitePlus;EPSD	ICGC	7.780	Loss
AGC_Akt_AKT1_ST	Q9BRQ0	PYGO2	P31749	AKT1	S48	N49H	49	Missense	proximal	1	no	14.059	13.970	PhosphoSitePlus	ICGC;COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	Q9BRQ0	PYGO2	P31749	AKT1	T50	N49H	49	Missense	proximal	-1	no	11.889	11.873	EPSD	ICGC;COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	Q00987	MDM2	P31749	AKT1	S17	G12R	12	Missense	distal	-5	no	5.495	9.559	EPSD	ICGC;COSMIC	7.780	Gain
AGC_Akt_AKT1_ST	Q00987	MDM2	P31749	AKT1	S186	S190C	190	Missense	distal	4	no	15.851	16.196	EPSD;PhosphoSitePlus	ICGC;COSMIC	7.780	Up-regulation
AGC_Akt_AKT1_ST	Q00987	MDM2	P31749	AKT1	S188	S190C	190	Missense	proximal	2	no	11.766	10.941	EPSD;PhosphoSitePlus	ICGC;COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	Q00987	MDM2	P31749	AKT1	S190	S190C	190	Missense	central	0	yes	9.490	0.000	EPSD	ICGC;COSMIC	7.780	Loss
AGC_Akt_AKT1_ST	Q00987	MDM2	P31749	AKT1	T419	V426F	426	Missense	distal	7	no	11.535	11.516	EPSD	ICGC	7.780	Down-regulation
AGC_Akt_AKT1_ST	Q96B36	AKT1S1	P31749	AKT1	T73	A75T	75	Missense	proximal	2	no	11.218	11.519	EPSD	ICGC;COSMIC	7.780	Up-regulation
AGC_Akt_AKT1_ST	Q96B36	AKT1S1	P31749	AKT1	T246	R243P	243	Missense	distal	-3	no	16.666	10.026	PhosphoSitePlus	ICGC;COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	Q13950	RUNX2	P31749	AKT1	T220	V221L	221	Missense	proximal	1	no	8.535	8.635	EPSD	ICGC	7.780	Up-regulation
AGC_Akt_AKT1_ST	O60825	PFKFB2	P31749	AKT1	S29	M23I	23	Missense	distal	-6	no	8.511	8.453	EPSD	ICGC	7.780	Down-regulation
AGC_Akt_AKT1_ST	O60825	PFKFB2	P31749	AKT1	T52	A48S	48	Missense	distal	-4	no	10.138	10.860	EPSD	ICGC	7.780	Up-regulation
AGC_Akt_AKT1_ST	O60825	PFKFB2	P31749	AKT1	S466	R463H	463	Missense	distal	-3	no	16.116	11.417	PhosphoSitePlus;EPSD	ICGC	7.780	Down-regulation
AGC_Akt_AKT1_ST	O60825	PFKFB2	P31749	AKT1	S466	R463P	463	Missense	distal	-3	no	16.116	9.476	PhosphoSitePlus;EPSD	ICGC	7.780	Down-regulation
AGC_Akt_AKT1_ST	O60825	PFKFB2	P31749	AKT1	T468	R463H	463	Missense	distal	-5	no	7.975	4.880	EPSD	ICGC	7.780	Loss
AGC_Akt_AKT1_ST	O60825	PFKFB2	P31749	AKT1	T468	R463P	463	Missense	distal	-5	no	7.975	3.965	EPSD	ICGC	7.780	Loss
AGC_Akt_AKT1_ST	Q14CB8	ARHGAP19	P31749	AKT1	S412	P405T	405	Missense	distal	-7	no	8.697	8.941	EPSD	ICGC	7.780	Up-regulation
AGC_Akt_AKT1_ST	Q14CB8	ARHGAP19	P31749	AKT1	S412	R419H	419	Missense	distal	7	no	8.697	8.625	EPSD	ICGC;COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	Q14CB8	ARHGAP19	P31749	AKT1	S420	S420L	420	Missense	central	0	yes	13.320	0.000	EPSD	ICGC;COSMIC	7.780	Loss
AGC_Akt_AKT1_ST	Q14CB8	ARHGAP19	P31749	AKT1	S420	R419H	419	Missense	proximal	-1	no	13.320	13.275	EPSD	ICGC;COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	Q14CB8	ARHGAP19	P31749	AKT1	S422	S420L	420	Missense	proximal	-2	no	15.684	14.828	PhosphoSitePlus	ICGC;COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	Q14CB8	ARHGAP19	P31749	AKT1	S422	R419H	419	Missense	distal	-3	no	15.684	10.986	PhosphoSitePlus	ICGC;COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	Q14CB8	ARHGAP19	P31749	AKT1	S422	R429W	429	Missense	distal	7	no	15.684	15.586	PhosphoSitePlus	ICGC;COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	Q14CB8	ARHGAP19	P31749	AKT1	S424	S420L	420	Missense	distal	-4	no	16.448	15.324	EPSD	ICGC;COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	Q14CB8	ARHGAP19	P31749	AKT1	S424	R419H	419	Missense	distal	-5	no	16.448	13.353	EPSD	ICGC;COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	Q14CB8	ARHGAP19	P31749	AKT1	S424	R429W	429	Missense	distal	5	no	16.448	16.353	EPSD	ICGC;COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	Q14CB8	ARHGAP19	P31749	AKT1	S468	R463M	463	Missense	distal	-5	no	9.604	5.081	EPSD	ICGC;COSMIC	7.780	Loss
AGC_Akt_AKT1_ST	Q96ST2	IWS1	P31749	AKT1	S131	R126M	126	Missense	distal	-5	no	9.249	4.726	EPSD	ICGC;COSMIC	7.780	Loss
AGC_Akt_AKT1_ST	Q96ST2	IWS1	P31749	AKT1	S157	A156T	156	Missense	proximal	-1	no	7.937	7.963	EPSD	ICGC;COSMIC	7.780	Up-regulation
AGC_Akt_AKT1_ST	Q96ST2	IWS1	P31749	AKT1	S362	R357K	357	Missense	distal	-5	no	11.875	9.478	EPSD	ICGC	7.780	Down-regulation
AGC_Akt_AKT1_ST	Q96ST2	IWS1	P31749	AKT1	S415	R412H	412	Missense	distal	-3	no	12.216	7.517	EPSD	ICGC;COSMIC	7.780	Loss
AGC_Akt_AKT1_ST	Q96ST2	IWS1	P31749	AKT1	S511	Q504K	504	Missense	distal	-7	no	8.095	8.276	EPSD	ICGC	7.780	Up-regulation
AGC_Akt_AKT1_ST	Q96ST2	IWS1	P31749	AKT1	S511	N516S	516	Missense	distal	5	no	8.095	8.129	EPSD	ICGC	7.780	Up-regulation
AGC_Akt_AKT1_ST	Q96ST2	IWS1	P31749	AKT1	T796	K800E	800	Missense	distal	4	no	11.209	11.310	EPSD	ICGC;COSMIC	7.780	Up-regulation
AGC_Akt_AKT1_ST	O60285	NUAK1	P31749	AKT1	S266	G268R	268	Missense	proximal	2	no	11.701	11.861	EPSD	ICGC;COSMIC	7.780	Up-regulation
AGC_Akt_AKT1_ST	O60285	NUAK1	P31749	AKT1	S266	S267R	267	Missense	proximal	1	no	11.701	11.846	EPSD	ICGC	7.780	Up-regulation
AGC_Akt_AKT1_ST	O60285	NUAK1	P31749	AKT1	S413	R410C	410	Missense	distal	-3	no	11.837	5.664	EPSD	ICGC;COSMIC	7.780	Loss
AGC_Akt_AKT1_ST	O60285	NUAK1	P31749	AKT1	S516	K522N	522	Missense	distal	6	no	8.923	8.845	EPSD	ICGC;COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	O60285	NUAK1	P31749	AKT1	S516	S514Y	514	Missense	proximal	-2	no	8.923	8.001	EPSD	ICGC;COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	O60285	NUAK1	P31749	AKT1	S518	K522N	522	Missense	distal	4	no	7.980	8.112	EPSD	ICGC;COSMIC	7.780	Up-regulation
AGC_Akt_AKT1_ST	O60285	NUAK1	P31749	AKT1	S518	S514Y	514	Missense	distal	-4	no	7.980	7.120	EPSD	ICGC;COSMIC	7.780	Loss
AGC_Akt_AKT1_ST	O60285	NUAK1	P31749	AKT1	S566	E559K	559	Missense	distal	-7	no	12.954	13.146	EPSD	ICGC;COSMIC	7.780	Up-regulation
AGC_Akt_AKT1_ST	O60285	NUAK1	P31749	AKT1	S566	R563Q	563	Missense	distal	-3	no	12.954	5.742	EPSD	ICGC	7.780	Loss
AGC_Akt_AKT1_ST	O60285	NUAK1	P31749	AKT1	S570	R563Q	563	Missense	distal	-7	no	12.692	12.498	EPSD	ICGC	7.780	Down-regulation
AGC_Akt_AKT1_ST	O60285	NUAK1	P31749	AKT1	S600	V602I	602	Missense	proximal	2	no	14.420	14.302	PhosphoSitePlus	ICGC	7.780	Down-regulation
AGC_Akt_AKT1_ST	O60285	NUAK1	P31749	AKT1	S636	D634E	634	Missense	proximal	-2	no	8.216	9.201	EPSD	ICGC	7.780	Up-regulation
AGC_Akt_AKT1_ST	O60285	NUAK1	P31749	AKT1	S636	L632M	632	Missense	distal	-4	no	8.216	8.431	EPSD	ICGC;COSMIC	7.780	Up-regulation
AGC_Akt_AKT1_ST	Q5XUX0	FBXO31	P31749	AKT1	T103	L101I	101	Missense	proximal	-2	no	9.387	9.003	EPSD	ICGC;COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	Q5XUX0	FBXO31	P31749	AKT1	T127	T127A	127	Missense	central	0	yes	8.142	0.000	EPSD	ICGC	7.780	Loss
AGC_Akt_AKT1_ST	Q5XUX0	FBXO31	P31749	AKT1	T127	R122W	122	Missense	distal	-5	no	8.142	2.622	EPSD	ICGC;COSMIC	7.780	Loss
AGC_Akt_AKT1_ST	Q5XUX0	FBXO31	P31749	AKT1	T127	D133E	133	Missense	distal	6	no	8.142	8.232	EPSD	ICGC	7.780	Up-regulation
AGC_Akt_AKT1_ST	Q5XUX0	FBXO31	P31749	AKT1	T127	C131F	131	Missense	distal	4	no	8.142	7.993	EPSD	ICGC;COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	Q5XUX0	FBXO31	P31749	AKT1	S400	P397F	397	Missense	distal	-3	no	6.975	8.020	EPSD	ICGC	7.780	Gain
AGC_Akt_AKT1_ST	Q5XUX0	FBXO31	P31749	AKT1	S403	R408M	408	Missense	distal	5	no	8.709	8.645	EPSD	ICGC;COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	Q5XUX0	FBXO31	P31749	AKT1	S403	P397F	397	Missense	distal	-6	no	8.709	8.699	EPSD	ICGC	7.780	Down-regulation
AGC_Akt_AKT1_ST	Q9Y283	INVS	P31749	AKT1	S126	C129F	129	Missense	distal	3	no	11.587	11.665	EPSD	ICGC;COSMIC	7.780	Up-regulation
AGC_Akt_AKT1_ST	Q9Y283	INVS	P31749	AKT1	S126	P127H	127	Missense	proximal	1	no	11.587	11.564	EPSD	ICGC;COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	Q9Y283	INVS	P31749	AKT1	S700	E694K	694	Missense	distal	-6	no	8.086	8.153	EPSD	ICGC	7.780	Up-regulation
AGC_Akt_AKT1_ST	Q9Y283	INVS	P31749	AKT1	S700	R706K	706	Missense	distal	6	no	8.086	8.098	EPSD	ICGC	7.780	Up-regulation
AGC_Akt_AKT1_ST	Q9UPY5	SLC7A11	P31749	AKT1	S8	G13V	13	Missense	distal	5	no	9.813	9.816	EPSD	ICGC;COSMIC	7.780	Up-regulation
AGC_Akt_AKT1_ST	Q9UPY5	SLC7A11	P31749	AKT1	S8	G13R	13	Missense	distal	5	no	9.813	9.883	EPSD	ICGC	7.780	Up-regulation
AGC_Akt_AKT1_ST	Q9UPY5	SLC7A11	P31749	AKT1	S26	V20I	20	Missense	distal	-6	no	10.440	10.396	PhosphoSitePlus	ICGC;COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	Q9UPY5	SLC7A11	P31749	AKT1	S26	L27M	27	Missense	proximal	1	no	10.440	10.279	PhosphoSitePlus	ICGC;COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	Q9UPY5	SLC7A11	P31749	AKT1	S51	V44I	44	Missense	distal	-7	no	9.889	9.795	EPSD	ICGC;COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	Q9UPY5	SLC7A11	P31749	AKT1	S481	L488S	488	Missense	distal	7	no	11.115	11.181	EPSD	ICGC	7.780	Up-regulation
AGC_Akt_AKT1_ST	Q9UPY5	SLC7A11	P31749	AKT1	S481	R478S	478	Missense	distal	-3	no	11.115	3.338	EPSD	ICGC	7.780	Loss
AGC_Akt_AKT1_ST	O43524	FOXO3	P31749	AKT1	S30	S26C	26	Missense	distal	-4	no	10.570	8.977	EPSD	ICGC;COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	O43524	FOXO3	P31749	AKT1	T32	S26C	26	Missense	distal	-6	no	15.456	15.309	PhosphoSitePlus;EPSD	ICGC;COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	O43524	FOXO3	P31749	AKT1	S75	G80S	80	Missense	distal	5	no	12.604	12.667	EPSD	ICGC;COSMIC	7.780	Up-regulation
AGC_Akt_AKT1_ST	O43524	FOXO3	P31749	AKT1	T179	K176R	176	Missense	distal	-3	no	6.680	11.200	EPSD	ICGC;COSMIC	7.780	Gain
AGC_Akt_AKT1_ST	O43524	FOXO3	P31749	AKT1	S181	K176R	176	Missense	distal	-5	no	7.056	9.454	EPSD	ICGC;COSMIC	7.780	Gain
AGC_Akt_AKT1_ST	O43524	FOXO3	P31749	AKT1	S253	R249L	249	Missense	distal	-4	no	16.516	15.307	EPSD;PhosphoSitePlus	ICGC;COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	O43524	FOXO3	P31749	AKT1	T313	A317T	317	Missense	distal	4	no	10.817	10.687	EPSD	ICGC;COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	O43524	FOXO3	P31749	AKT1	S315	A317T	317	Missense	proximal	2	no	16.048	16.349	EPSD	ICGC;COSMIC	7.780	Up-regulation
AGC_Akt_AKT1_ST	O43524	FOXO3	P31749	AKT1	S413	P415L	415	Missense	proximal	2	no	11.407	11.198	EPSD	ICGC;COSMIC;GDSC	7.780	Down-regulation
AGC_Akt_AKT1_ST	O43524	FOXO3	P31749	AKT1	S413	G420S	420	Missense	distal	7	no	11.407	11.480	EPSD	ICGC;COSMIC	7.780	Up-regulation
AGC_Akt_AKT1_ST	O43524	FOXO3	P31749	AKT1	S413	F414L	414	Missense	proximal	1	no	11.407	11.488	EPSD	ICGC	7.780	Up-regulation
AGC_Akt_AKT1_ST	O43524	FOXO3	P31749	AKT1	S551	R548C	548	Missense	distal	-3	no	11.257	5.083	EPSD	ICGC;COSMIC	7.780	Loss
AGC_Akt_AKT1_ST	O43524	FOXO3	P31749	AKT1	S553	R548C	548	Missense	distal	-5	no	9.351	5.274	EPSD	ICGC;COSMIC	7.780	Loss
AGC_Akt_AKT1_ST	O43524	FOXO3	P31749	AKT1	S666	S669I	669	Missense	distal	3	no	8.863	8.732	EPSD	ICGC;COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	P46527	CDKN1B	P31749	AKT1	S10	N8K	8	Missense	proximal	-2	no	9.798	10.734	EPSD;PhosphoSitePlus	ICGC;COSMIC	7.780	Up-regulation
AGC_Akt_AKT1_ST	P46527	CDKN1B	P31749	AKT1	S12	N8K	8	Missense	distal	-4	no	7.429	8.069	EPSD	ICGC;COSMIC	7.780	Gain
AGC_Akt_AKT1_ST	P46527	CDKN1B	P31749	AKT1	T157	Q163E	163	Missense	distal	6	no	13.829	13.843	PhosphoSitePlus;EPSD	ICGC;COSMIC	7.780	Up-regulation
AGC_Akt_AKT1_ST	P46527	CDKN1B	P31749	AKT1	T157	S160F	160	Missense	distal	3	no	13.829	13.731	PhosphoSitePlus;EPSD	ICGC;COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	P46527	CDKN1B	P31749	AKT1	T157	T162I	162	Missense	distal	5	no	13.829	13.732	PhosphoSitePlus;EPSD	ICGC;COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	P46527	CDKN1B	P31749	AKT1	T198	G192V	192	Missense	distal	-6	no	12.810	12.814	EPSD;PhosphoSitePlus	ICGC	7.780	Up-regulation
AGC_Akt_AKT1_ST	P46527	CDKN1B	P31749	AKT1	T198	P191H	191	Missense	distal	-7	no	12.810	12.759	EPSD;PhosphoSitePlus	ICGC;COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	P84103	SRSF3	P31749	AKT1	S95	W96C	96	Missense	proximal	1	no	8.835	8.599	EPSD	ICGC	7.780	Down-regulation
AGC_Akt_AKT1_ST	P84103	SRSF3	P31749	AKT1	S95	G91S	91	Missense	distal	-4	no	8.835	9.564	EPSD	ICGC;COSMIC	7.780	Up-regulation
AGC_Akt_AKT1_ST	P84103	SRSF3	P31749	AKT1	S95	P100S	100	Missense	distal	5	no	8.835	8.887	EPSD	ICGC;COSMIC	7.780	Up-regulation
AGC_Akt_AKT1_ST	P84103	SRSF3	P31749	AKT1	S95	R98L	98	Missense	distal	3	no	8.835	8.753	EPSD	ICGC;COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	P84103	SRSF3	P31749	AKT1	S95	D102Y	102	Missense	distal	7	no	8.835	8.869	EPSD	ICGC;COSMIC	7.780	Up-regulation
AGC_Akt_AKT1_ST	P84103	SRSF3	P31749	AKT1	S108	D102Y	102	Missense	distal	-6	no	10.457	10.516	EPSD	ICGC;COSMIC	7.780	Up-regulation
AGC_Akt_AKT1_ST	P84103	SRSF3	P31749	AKT1	S115	R118M	118	Missense	distal	3	no	12.485	12.416	EPSD	ICGC;COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	P84103	SRSF3	P31749	AKT1	S120	R118M	118	Missense	proximal	-2	no	11.984	11.332	EPSD	ICGC;COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	P84103	SRSF3	P31749	AKT1	S122	R118M	118	Missense	distal	-4	no	16.112	15.117	EPSD;PhosphoSitePlus	ICGC;COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	P84103	SRSF3	P31749	AKT1	S124	R118M	118	Missense	distal	-6	no	10.269	10.172	EPSD	ICGC;COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	P84103	SRSF3	P31749	AKT1	S128	R134I	134	Missense	distal	6	no	17.309	17.146	PhosphoSitePlus;EPSD	ICGC	7.780	Down-regulation
AGC_Akt_AKT1_ST	P84103	SRSF3	P31749	AKT1	S130	R134I	134	Missense	distal	4	no	16.169	16.420	EPSD;PhosphoSitePlus	ICGC	7.780	Up-regulation
AGC_Akt_AKT1_ST	P84103	SRSF3	P31749	AKT1	S130	E136G	136	Missense	distal	6	no	16.169	16.123	EPSD;PhosphoSitePlus	ICGC;COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	P84103	SRSF3	P31749	AKT1	S138	R134I	134	Missense	distal	-4	no	16.412	14.944	EPSD;PhosphoSitePlus	ICGC	7.780	Down-regulation
AGC_Akt_AKT1_ST	P84103	SRSF3	P31749	AKT1	S138	R141Q	141	Missense	distal	3	no	16.412	16.356	EPSD;PhosphoSitePlus	ICGC;COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	P84103	SRSF3	P31749	AKT1	S138	E136G	136	Missense	proximal	-2	no	16.412	16.125	EPSD;PhosphoSitePlus	ICGC;COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	P84103	SRSF3	P31749	AKT1	S140	R134I	134	Missense	distal	-6	no	16.590	16.435	EPSD;PhosphoSitePlus	ICGC	7.780	Down-regulation
AGC_Akt_AKT1_ST	P84103	SRSF3	P31749	AKT1	S140	R141Q	141	Missense	proximal	1	no	16.590	16.295	EPSD;PhosphoSitePlus	ICGC;COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	P84103	SRSF3	P31749	AKT1	S140	E136G	136	Missense	distal	-4	no	16.590	16.372	EPSD;PhosphoSitePlus	ICGC;COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	P84103	SRSF3	P31749	AKT1	S148	S152C	152	Missense	distal	4	no	13.610	13.955	EPSD	ICGC;COSMIC	7.780	Up-regulation
AGC_Akt_AKT1_ST	P84103	SRSF3	P31749	AKT1	S148	R141Q	141	Missense	distal	-7	no	13.610	13.416	EPSD	ICGC;COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	P84103	SRSF3	P31749	AKT1	S150	S152C	152	Missense	proximal	2	no	10.841	10.016	EPSD	ICGC;COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	P84103	SRSF3	P31749	AKT1	S152	S152C	152	Missense	central	0	yes	14.444	0.000	EPSD	ICGC;COSMIC	7.780	Loss
AGC_Akt_AKT1_ST	P84103	SRSF3	P31749	AKT1	S154	S152C	152	Missense	proximal	-2	no	14.977	13.325	EPSD	ICGC;COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	P84103	SRSF3	P31749	AKT1	S156	S152C	152	Missense	distal	-4	no	15.818	14.225	EPSD	ICGC;COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	P84103	SRSF3	P31749	AKT1	S158	S152C	152	Missense	distal	-6	no	18.645	18.498	EPSD	ICGC;COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	Q13188	STK3	P31749	AKT1	T384	M379T	379	Missense	distal	-5	no	10.753	11.545	PhosphoSitePlus;EPSD	ICGC;COSMIC	7.780	Up-regulation
AGC_Akt_AKT1_ST	Q13188	STK3	P31749	AKT1	T384	M379I	379	Missense	distal	-5	no	10.753	10.707	PhosphoSitePlus;EPSD	ICGC	7.780	Down-regulation
AGC_Akt_AKT1_ST	Q92794	KAT6A	P31749	AKT1	T332	R330C	330	Missense	proximal	-2	no	9.379	7.915	EPSD	ICGC;COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	Q92794	KAT6A	P31749	AKT1	T332	Q326K	326	Missense	distal	-6	no	9.379	9.449	EPSD	ICGC	7.780	Up-regulation
AGC_Akt_AKT1_ST	Q92794	KAT6A	P31749	AKT1	T369	S372R	372	Missense	distal	3	no	17.379	17.363	PhosphoSitePlus	ICGC	7.780	Down-regulation
AGC_Akt_AKT1_ST	Q92794	KAT6A	P31749	AKT1	T369	K365T	365	Missense	distal	-4	no	17.379	17.363	PhosphoSitePlus	ICGC;COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	Q92794	KAT6A	P31749	AKT1	S371	S372R	372	Missense	proximal	1	no	11.150	11.294	EPSD	ICGC	7.780	Up-regulation
AGC_Akt_AKT1_ST	Q92794	KAT6A	P31749	AKT1	S371	K365T	365	Missense	distal	-6	no	11.150	11.160	EPSD	ICGC;COSMIC	7.780	Up-regulation
AGC_Akt_AKT1_ST	Q92794	KAT6A	P31749	AKT1	S377	S372R	372	Missense	distal	-5	no	3.968	8.439	EPSD	ICGC	7.780	Gain
AGC_Akt_AKT1_ST	Q92794	KAT6A	P31749	AKT1	S399	S396N	396	Missense	distal	-3	no	7.654	7.954	EPSD	ICGC;COSMIC	7.780	Gain
AGC_Akt_AKT1_ST	Q92794	KAT6A	P31749	AKT1	S812	S816P	816	Missense	distal	4	no	8.450	8.606	EPSD	ICGC;COSMIC	7.780	Up-regulation
AGC_Akt_AKT1_ST	Q92794	KAT6A	P31749	AKT1	S941	V944L	944	Missense	distal	3	no	11.309	11.301	EPSD	ICGC;COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	Q92794	KAT6A	P31749	AKT1	S974	D977V	977	Missense	distal	3	no	11.254	11.275	EPSD	ICGC	7.780	Up-regulation
AGC_Akt_AKT1_ST	Q92794	KAT6A	P31749	AKT1	S1001	L1005I	1005	Missense	distal	4	no	11.664	11.737	EPSD	ICGC;COSMIC	7.780	Up-regulation
AGC_Akt_AKT1_ST	Q92794	KAT6A	P31749	AKT1	S1001	P997A	997	Missense	distal	-4	no	11.664	11.678	EPSD	ICGC;COSMIC	7.780	Up-regulation
AGC_Akt_AKT1_ST	Q92794	KAT6A	P31749	AKT1	S1001	S1000I	1000	Missense	proximal	-1	no	11.664	11.615	EPSD	ICGC;COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	Q92794	KAT6A	P31749	AKT1	S1089	R1095K	1095	Missense	distal	6	no	10.985	10.997	EPSD	ICGC;COSMIC	7.780	Up-regulation
AGC_Akt_AKT1_ST	Q92794	KAT6A	P31749	AKT1	S1090	R1095K	1095	Missense	distal	5	no	13.066	13.060	EPSD	ICGC;COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	Q92794	KAT6A	P31749	AKT1	S1136	K1134R	1134	Missense	proximal	-2	no	8.489	8.049	EPSD	ICGC;COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	Q92794	KAT6A	P31749	AKT1	S1136	K1134N	1134	Missense	proximal	-2	no	8.489	7.552	EPSD	ICGC	7.780	Loss
AGC_Akt_AKT1_ST	Q92794	KAT6A	P31749	AKT1	S1861	A1862V	1862	Missense	proximal	1	no	10.348	10.420	EPSD	ICGC	7.780	Up-regulation
AGC_Akt_AKT1_ST	Q9UKV3	ACIN1	P31749	AKT1	T9	W2C	2	Missense	distal	-7	no	11.750	11.694	EPSD	ICGC;COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	Q9UKV3	ACIN1	P31749	AKT1	T9	R8P	8	Missense	proximal	-1	no	11.750	11.711	EPSD	ICGC;COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	Q9UKV3	ACIN1	P31749	AKT1	T9	H6Y	6	Missense	distal	-3	no	11.750	8.859	EPSD	ICGC	7.780	Down-regulation
AGC_Akt_AKT1_ST	Q9UKV3	ACIN1	P31749	AKT1	S10	R8P	8	Missense	proximal	-2	no	8.812	8.177	EPSD	ICGC;COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	Q9UKV3	ACIN1	P31749	AKT1	S10	H6Y	6	Missense	distal	-4	no	8.812	8.926	EPSD	ICGC	7.780	Up-regulation
AGC_Akt_AKT1_ST	Q9UKV3	ACIN1	P31749	AKT1	T13	R8P	8	Missense	distal	-5	no	8.479	4.469	EPSD	ICGC;COSMIC	7.780	Loss
AGC_Akt_AKT1_ST	Q9UKV3	ACIN1	P31749	AKT1	T13	H6Y	6	Missense	distal	-7	no	8.479	8.518	EPSD	ICGC	7.780	Up-regulation
AGC_Akt_AKT1_ST	Q9UKV3	ACIN1	P31749	AKT1	S206	P203H	203	Missense	distal	-3	no	7.109	9.050	EPSD	ICGC	7.780	Gain
AGC_Akt_AKT1_ST	Q9UKV3	ACIN1	P31749	AKT1	S207	P203H	203	Missense	distal	-4	no	10.916	10.679	EPSD	ICGC	7.780	Down-regulation
AGC_Akt_AKT1_ST	Q9UKV3	ACIN1	P31749	AKT1	S207	P203T	203	Missense	distal	-4	no	10.916	11.708	EPSD	ICGC	7.780	Up-regulation
AGC_Akt_AKT1_ST	Q9UKV3	ACIN1	P31749	AKT1	S207	E212Q	212	Missense	distal	5	no	10.916	10.905	EPSD	ICGC;COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	Q9UKV3	ACIN1	P31749	AKT1	S208	P203H	203	Missense	distal	-5	no	7.840	8.755	EPSD	ICGC	7.780	Up-regulation
AGC_Akt_AKT1_ST	Q9UKV3	ACIN1	P31749	AKT1	S208	P203T	203	Missense	distal	-5	no	7.840	8.120	EPSD	ICGC	7.780	Up-regulation
AGC_Akt_AKT1_ST	Q9UKV3	ACIN1	P31749	AKT1	S208	E212Q	212	Missense	distal	4	no	7.840	7.896	EPSD	ICGC;COSMIC	7.780	Up-regulation
AGC_Akt_AKT1_ST	Q9UKV3	ACIN1	P31749	AKT1	S229	R235I	235	Missense	distal	6	no	11.478	11.315	EPSD	ICGC;COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	Q9UKV3	ACIN1	P31749	AKT1	S229	S229A	229	Missense	central	0	yes	11.478	0.000	EPSD	ICGC;COSMIC	7.780	Loss
AGC_Akt_AKT1_ST	Q9UKV3	ACIN1	P31749	AKT1	S229	R222C	222	Missense	distal	-7	no	11.478	10.999	EPSD	ICGC;COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	Q9UKV3	ACIN1	P31749	AKT1	S240	R235I	235	Missense	distal	-5	no	9.060	4.492	EPSD	ICGC;COSMIC	7.780	Loss
AGC_Akt_AKT1_ST	Q9UKV3	ACIN1	P31749	AKT1	T326	T326K	326	Missense	central	0	yes	10.447	0.000	EPSD	ICGC	7.780	Loss
AGC_Akt_AKT1_ST	Q9UKV3	ACIN1	P31749	AKT1	T326	Q331K	331	Missense	distal	5	no	10.447	10.492	EPSD	ICGC	7.780	Up-regulation
AGC_Akt_AKT1_ST	Q9UKV3	ACIN1	P31749	AKT1	T326	R327S	327	Missense	proximal	1	no	10.447	10.302	EPSD	ICGC;COSMIC;GDSC	7.780	Down-regulation
AGC_Akt_AKT1_ST	Q9UKV3	ACIN1	P31749	AKT1	T326	P324A	324	Missense	proximal	-2	no	10.447	10.820	EPSD	ICGC;COSMIC	7.780	Up-regulation
AGC_Akt_AKT1_ST	Q9UKV3	ACIN1	P31749	AKT1	S328	T326K	326	Missense	proximal	-2	no	10.539	10.856	EPSD	ICGC	7.780	Up-regulation
AGC_Akt_AKT1_ST	Q9UKV3	ACIN1	P31749	AKT1	S328	Q331K	331	Missense	distal	3	no	10.539	10.614	EPSD	ICGC	7.780	Up-regulation
AGC_Akt_AKT1_ST	Q9UKV3	ACIN1	P31749	AKT1	S328	R327S	327	Missense	proximal	-1	no	10.539	10.528	EPSD	ICGC;COSMIC;GDSC	7.780	Down-regulation
AGC_Akt_AKT1_ST	Q9UKV3	ACIN1	P31749	AKT1	S328	P324A	324	Missense	distal	-4	no	10.539	10.553	EPSD	ICGC;COSMIC	7.780	Up-regulation
AGC_Akt_AKT1_ST	Q9UKV3	ACIN1	P31749	AKT1	S365	E360K	360	Missense	distal	-5	no	6.183	7.881	EPSD	ICGC	7.780	Gain
AGC_Akt_AKT1_ST	Q9UKV3	ACIN1	P31749	AKT1	S377	S384L	384	Missense	distal	7	no	8.358	8.292	EPSD	ICGC;COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	Q9UKV3	ACIN1	P31749	AKT1	S377	S384P	384	Missense	distal	7	no	8.358	8.300	EPSD	ICGC;COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	Q9UKV3	ACIN1	P31749	AKT1	S377	S376F	376	Missense	proximal	-1	no	8.358	8.323	EPSD	ICGC;COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	Q9UKV3	ACIN1	P31749	AKT1	S377	G379D	379	Missense	proximal	2	no	8.358	8.091	EPSD	ICGC;COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	Q9UKV3	ACIN1	P31749	AKT1	S386	S384L	384	Missense	proximal	-2	no	8.920	8.064	EPSD	ICGC;COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	Q9UKV3	ACIN1	P31749	AKT1	S386	S384P	384	Missense	proximal	-2	no	8.920	8.096	EPSD	ICGC;COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	Q9UKV3	ACIN1	P31749	AKT1	S386	G379D	379	Missense	distal	-7	no	8.920	8.735	EPSD	ICGC;COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	Q9UKV3	ACIN1	P31749	AKT1	S388	S384L	384	Missense	distal	-4	no	10.362	9.238	EPSD	ICGC;COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	Q9UKV3	ACIN1	P31749	AKT1	S388	S384P	384	Missense	distal	-4	no	10.362	9.626	EPSD	ICGC;COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	Q9UKV3	ACIN1	P31749	AKT1	S424	P428L	428	Missense	distal	4	no	8.061	8.093	EPSD	ICGC	7.780	Up-regulation
AGC_Akt_AKT1_ST	Q9UKV3	ACIN1	P31749	AKT1	S467	S467P	467	Missense	central	0	yes	7.876	0.000	EPSD	ICGC;COSMIC	7.780	Loss
AGC_Akt_AKT1_ST	Q9UKV3	ACIN1	P31749	AKT1	S467	S467F	467	Missense	central	0	yes	7.876	0.000	EPSD	ICGC	7.780	Loss
AGC_Akt_AKT1_ST	Q9UKV3	ACIN1	P31749	AKT1	S467	E463K	463	Missense	distal	-4	no	7.876	8.460	EPSD	ICGC	7.780	Up-regulation
AGC_Akt_AKT1_ST	Q9UKV3	ACIN1	P31749	AKT1	S561	K555R	555	Missense	distal	-6	no	10.184	10.198	EPSD	ICGC;COSMIC	7.780	Up-regulation
AGC_Akt_AKT1_ST	Q9UKV3	ACIN1	P31749	AKT1	S561	S567R	567	Missense	distal	6	no	10.184	10.182	EPSD	ICGC	7.780	Down-regulation
AGC_Akt_AKT1_ST	Q9UKV3	ACIN1	P31749	AKT1	S561	L564P	564	Missense	distal	3	no	10.184	10.200	EPSD	ICGC;COSMIC	7.780	Up-regulation
AGC_Akt_AKT1_ST	Q9UKV3	ACIN1	P31749	AKT1	T563	S567R	567	Missense	distal	4	no	8.730	8.741	EPSD	ICGC	7.780	Up-regulation
AGC_Akt_AKT1_ST	Q9UKV3	ACIN1	P31749	AKT1	T563	L564P	564	Missense	proximal	1	no	8.730	8.476	EPSD	ICGC;COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	Q9UKV3	ACIN1	P31749	AKT1	S583	S584T	584	Missense	proximal	1	no	12.629	12.822	EPSD	ICGC;COSMIC	7.780	Up-regulation
AGC_Akt_AKT1_ST	Q9UKV3	ACIN1	P31749	AKT1	S585	S584T	584	Missense	proximal	-1	no	10.277	10.283	EPSD	ICGC;COSMIC	7.780	Up-regulation
AGC_Akt_AKT1_ST	Q9UKV3	ACIN1	P31749	AKT1	S585	S588T	588	Missense	distal	3	no	10.277	10.276	EPSD	ICGC;COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	Q9UKV3	ACIN1	P31749	AKT1	S593	S588T	588	Missense	distal	-5	no	13.530	14.271	EPSD	ICGC;COSMIC	7.780	Up-regulation
AGC_Akt_AKT1_ST	Q9UKV3	ACIN1	P31749	AKT1	S595	S588T	588	Missense	distal	-7	no	16.348	16.398	EPSD	ICGC;COSMIC	7.780	Up-regulation
AGC_Akt_AKT1_ST	Q9UKV3	ACIN1	P31749	AKT1	S599	P606L	606	Missense	distal	7	no	9.211	9.203	EPSD	ICGC	7.780	Down-regulation
AGC_Akt_AKT1_ST	Q9UKV3	ACIN1	P31749	AKT1	S605	P606L	606	Missense	proximal	1	no	10.344	10.598	EPSD	ICGC	7.780	Up-regulation
AGC_Akt_AKT1_ST	Q9UKV3	ACIN1	P31749	AKT1	S631	S631C	631	Missense	central	0	yes	10.506	0.000	EPSD	ICGC;COSMIC	7.780	Loss
AGC_Akt_AKT1_ST	Q9UKV3	ACIN1	P31749	AKT1	S635	S631C	631	Missense	distal	-4	no	13.515	11.922	EPSD	ICGC;COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	Q9UKV3	ACIN1	P31749	AKT1	S635	R642H	642	Missense	distal	7	no	13.515	13.443	EPSD	ICGC;COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	Q9UKV3	ACIN1	P31749	AKT1	S637	S631C	631	Missense	distal	-6	no	9.196	9.050	EPSD	ICGC;COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	Q9UKV3	ACIN1	P31749	AKT1	S637	R642H	642	Missense	distal	5	no	9.196	9.122	EPSD	ICGC;COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	Q9UKV3	ACIN1	P31749	AKT1	S643	S650G	650	Missense	distal	7	no	16.166	16.093	EPSD	ICGC;COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	Q9UKV3	ACIN1	P31749	AKT1	S643	R642H	642	Missense	proximal	-1	no	16.166	16.122	EPSD	ICGC;COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	Q9UKV3	ACIN1	P31749	AKT1	S645	S650G	650	Missense	distal	5	no	16.880	16.817	EPSD	ICGC;COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	Q9UKV3	ACIN1	P31749	AKT1	S645	N651K	651	Missense	distal	6	no	16.880	16.958	EPSD	ICGC	7.780	Up-regulation
AGC_Akt_AKT1_ST	Q9UKV3	ACIN1	P31749	AKT1	S645	R642H	642	Missense	distal	-3	no	16.880	12.181	EPSD	ICGC;COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	Q9UKV3	ACIN1	P31749	AKT1	S647	S650G	650	Missense	distal	3	no	16.700	16.609	EPSD	ICGC;COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	Q9UKV3	ACIN1	P31749	AKT1	S647	N651K	651	Missense	distal	4	no	16.700	16.568	EPSD	ICGC	7.780	Down-regulation
AGC_Akt_AKT1_ST	Q9UKV3	ACIN1	P31749	AKT1	S647	R642H	642	Missense	distal	-5	no	16.700	13.605	EPSD	ICGC;COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	Q9UKV3	ACIN1	P31749	AKT1	S649	S650G	650	Missense	proximal	1	no	15.202	14.898	EPSD	ICGC;COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	Q9UKV3	ACIN1	P31749	AKT1	S649	N651K	651	Missense	proximal	2	no	15.202	15.488	EPSD	ICGC	7.780	Up-regulation
AGC_Akt_AKT1_ST	Q9UKV3	ACIN1	P31749	AKT1	S649	R642H	642	Missense	distal	-7	no	15.202	14.901	EPSD	ICGC;COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	Q9UKV3	ACIN1	P31749	AKT1	S665	S661F	661	Missense	distal	-4	no	11.178	10.011	EPSD	ICGC;COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	Q9UKV3	ACIN1	P31749	AKT1	S665	S664R	664	Missense	proximal	-1	no	11.178	11.189	EPSD	ICGC	7.780	Up-regulation
AGC_Akt_AKT1_ST	Q9UKV3	ACIN1	P31749	AKT1	S665	R662S	662	Missense	distal	-3	no	11.178	3.402	EPSD	ICGC;COSMIC	7.780	Loss
AGC_Akt_AKT1_ST	Q9UKV3	ACIN1	P31749	AKT1	S665	T671S	671	Missense	distal	6	no	11.178	11.158	EPSD	ICGC;COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	Q9UKV3	ACIN1	P31749	AKT1	S665	T666A	666	Missense	proximal	1	no	11.178	10.911	EPSD	ICGC	7.780	Down-regulation
AGC_Akt_AKT1_ST	Q9UKV3	ACIN1	P31749	AKT1	S665	S665R	665	Missense	central	0	yes	11.178	0.000	EPSD	ICGC;COSMIC	7.780	Loss
AGC_Akt_AKT1_ST	Q9UKV3	ACIN1	P31749	AKT1	S665	P658H	658	Missense	distal	-7	no	11.178	11.127	EPSD	ICGC;COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	Q9UKV3	ACIN1	P31749	AKT1	S665	R662M	662	Missense	distal	-3	no	11.178	3.673	EPSD	ICGC;COSMIC	7.780	Loss
AGC_Akt_AKT1_ST	Q9UKV3	ACIN1	P31749	AKT1	S667	S664R	664	Missense	distal	-3	no	6.843	14.619	EPSD	ICGC	7.780	Gain
AGC_Akt_AKT1_ST	Q9UKV3	ACIN1	P31749	AKT1	T669	S664R	664	Missense	distal	-5	no	4.734	9.205	EPSD	ICGC	7.780	Gain
AGC_Akt_AKT1_ST	Q9UKV3	ACIN1	P31749	AKT1	T699	P693T	693	Missense	distal	-6	no	12.101	12.196	EPSD	ICGC	7.780	Up-regulation
AGC_Akt_AKT1_ST	Q9UKV3	ACIN1	P31749	AKT1	T699	T697I	697	Missense	proximal	-2	no	12.101	10.926	EPSD	ICGC	7.780	Down-regulation
AGC_Akt_AKT1_ST	Q9UKV3	ACIN1	P31749	AKT1	S701	T697I	697	Missense	distal	-4	no	9.519	8.081	EPSD	ICGC	7.780	Down-regulation
AGC_Akt_AKT1_ST	Q9UKV3	ACIN1	P31749	AKT1	S710	P712L	712	Missense	proximal	2	no	11.643	11.433	EPSD	ICGC;COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	Q07352	ZFP36L1	P31749	AKT1	S54	P50S	50	Missense	distal	-4	no	11.489	12.225	EPSD	ICGC;COSMIC	7.780	Up-regulation
AGC_Akt_AKT1_ST	Q07352	ZFP36L1	P31749	AKT1	T56	H63Y	63	Missense	distal	7	no	10.539	10.561	EPSD	ICGC;COSMIC	7.780	Up-regulation
AGC_Akt_AKT1_ST	Q07352	ZFP36L1	P31749	AKT1	T56	P50S	50	Missense	distal	-6	no	10.539	10.603	EPSD	ICGC;COSMIC	7.780	Up-regulation
AGC_Akt_AKT1_ST	Q07352	ZFP36L1	P31749	AKT1	T148	T155K	155	Missense	distal	7	no	10.497	10.487	EPSD	ICGC	7.780	Down-regulation
AGC_Akt_AKT1_ST	Q07352	ZFP36L1	P31749	AKT1	S192	R197C	197	Missense	distal	5	no	10.035	9.909	EPSD	ICGC;COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	Q07352	ZFP36L1	P31749	AKT1	S192	A193T	193	Missense	proximal	1	no	10.035	10.302	EPSD	ICGC	7.780	Up-regulation
AGC_Akt_AKT1_ST	Q07352	ZFP36L1	P31749	AKT1	S192	P196L	196	Missense	distal	4	no	10.035	10.067	EPSD	ICGC;COSMIC	7.780	Up-regulation
AGC_Akt_AKT1_ST	Q07352	ZFP36L1	P31749	AKT1	S192	R189L	189	Missense	distal	-3	no	10.035	3.041	EPSD	ICGC;COSMIC	7.780	Loss
AGC_Akt_AKT1_ST	Q07352	ZFP36L1	P31749	AKT1	S203	R197C	197	Missense	distal	-6	no	8.916	8.736	EPSD;PhosphoSitePlus	ICGC;COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	Q07352	ZFP36L1	P31749	AKT1	S203	G206W	206	Missense	distal	3	no	8.916	8.878	EPSD;PhosphoSitePlus	ICGC;COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	Q07352	ZFP36L1	P31749	AKT1	S203	S203N	203	Missense	central	0	yes	8.916	0.000	EPSD;PhosphoSitePlus	ICGC	7.780	Loss
AGC_Akt_AKT1_ST	Q07352	ZFP36L1	P31749	AKT1	S203	P196L	196	Missense	distal	-7	no	8.916	8.876	EPSD;PhosphoSitePlus	ICGC;COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	Q07352	ZFP36L1	P31749	AKT1	S331	S334F	334	Missense	distal	3	no	9.959	9.860	EPSD	ICGC;COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	Q9Y3C5	RNF11	P31749	AKT1	T135	C136F	136	Missense	proximal	1	no	11.853	12.255	PhosphoSitePlus	ICGC	7.780	Up-regulation
AGC_Akt_AKT1_ST	Q9Y3C5	RNF11	P31749	AKT1	T135	P137S	137	Missense	proximal	2	no	11.853	12.190	PhosphoSitePlus	ICGC;COSMIC	7.780	Up-regulation
AGC_Akt_AKT1_ST	Q9Y3C5	RNF11	P31749	AKT1	T135	W129L	129	Missense	distal	-6	no	11.853	11.916	PhosphoSitePlus	ICGC;COSMIC	7.780	Up-regulation
AGC_Akt_AKT1_ST	Q14315	FLNC	P31749	AKT1	S339	G346E	346	Missense	distal	7	no	8.351	8.391	EPSD	ICGC;COSMIC	7.780	Up-regulation
AGC_Akt_AKT1_ST	Q14315	FLNC	P31749	AKT1	T423	G419V	419	Missense	distal	-4	no	9.759	9.394	EPSD	ICGC	7.780	Down-regulation
AGC_Akt_AKT1_ST	Q14315	FLNC	P31749	AKT1	S868	P863R	863	Missense	distal	-5	no	6.903	10.914	EPSD	ICGC	7.780	Gain
AGC_Akt_AKT1_ST	Q14315	FLNC	P31749	AKT1	S1005	P1006S	1006	Missense	proximal	1	no	10.467	10.622	EPSD	ICGC;COSMIC	7.780	Up-regulation
AGC_Akt_AKT1_ST	Q14315	FLNC	P31749	AKT1	S1005	R1002W	1002	Missense	distal	-3	no	10.467	1.526	EPSD	ICGC;COSMIC	7.780	Loss
AGC_Akt_AKT1_ST	Q14315	FLNC	P31749	AKT1	S1007	P1006S	1006	Missense	proximal	-1	no	9.815	9.844	EPSD	ICGC;COSMIC	7.780	Up-regulation
AGC_Akt_AKT1_ST	Q14315	FLNC	P31749	AKT1	S1007	R1002W	1002	Missense	distal	-5	no	9.815	4.295	EPSD	ICGC;COSMIC	7.780	Loss
AGC_Akt_AKT1_ST	Q14315	FLNC	P31749	AKT1	T1281	T1274S	1274	Missense	distal	-7	no	12.372	12.322	EPSD	ICGC	7.780	Down-regulation
AGC_Akt_AKT1_ST	Q14315	FLNC	P31749	AKT1	T1281	G1284C	1284	Missense	distal	3	no	12.372	12.286	EPSD	ICGC	7.780	Down-regulation
AGC_Akt_AKT1_ST	Q14315	FLNC	P31749	AKT1	S1745	H1740R	1740	Missense	distal	-5	no	6.980	10.075	EPSD	ICGC;COSMIC	7.780	Gain
AGC_Akt_AKT1_ST	Q14315	FLNC	P31749	AKT1	S1985	P1990L	1990	Missense	distal	5	no	10.952	10.938	EPSD	ICGC	7.780	Down-regulation
AGC_Akt_AKT1_ST	Q14315	FLNC	P31749	AKT1	S2077	G2072R	2072	Missense	distal	-5	no	4.244	8.309	EPSD	ICGC	7.780	Gain
AGC_Akt_AKT1_ST	Q14315	FLNC	P31749	AKT1	T2139	E2136K	2136	Missense	distal	-3	no	6.365	8.416	EPSD	ICGC	7.780	Gain
AGC_Akt_AKT1_ST	Q14315	FLNC	P31749	AKT1	T2179	R2180H	2180	Missense	proximal	1	no	12.798	12.476	EPSD	ICGC;COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	Q14315	FLNC	P31749	AKT1	T2179	R2173H	2173	Missense	distal	-6	no	12.798	12.679	EPSD	ICGC;COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	Q14315	FLNC	P31749	AKT1	T2179	R2173Q	2173	Missense	distal	-6	no	12.798	12.714	EPSD	ICGC	7.780	Down-regulation
AGC_Akt_AKT1_ST	Q14315	FLNC	P31749	AKT1	S2181	R2180H	2180	Missense	proximal	-1	no	11.571	11.526	EPSD	ICGC;COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	Q14315	FLNC	P31749	AKT1	S2233	R2228L	2228	Missense	distal	-5	no	15.302	11.175	PhosphoSitePlus	ICGC;COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	Q14315	FLNC	P31749	AKT1	S2233	R2230C	2230	Missense	distal	-3	no	15.302	9.128	PhosphoSitePlus	ICGC	7.780	Down-regulation
AGC_Akt_AKT1_ST	Q14315	FLNC	P31749	AKT1	T2412	R2410Q	2410	Missense	proximal	-2	no	12.147	11.634	EPSD	ICGC;COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	Q14315	FLNC	P31749	AKT1	T2414	R2410Q	2410	Missense	distal	-4	no	9.293	8.672	EPSD	ICGC;COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	Q14315	FLNC	P31749	AKT1	T2446	V2439L	2439	Missense	distal	-7	no	8.924	8.968	EPSD	ICGC	7.780	Up-regulation
AGC_Akt_AKT1_ST	Q15027	ACAP1	P31749	AKT1	S554	R556T	556	Missense	proximal	2	no	15.577	15.674	PhosphoSitePlus	ICGC;COSMIC	7.780	Up-regulation
AGC_Akt_AKT1_ST	Q13107	USP4	P31749	AKT1	S231	S234L	234	Missense	distal	3	no	7.799	7.701	EPSD	ICGC	7.780	Loss
AGC_Akt_AKT1_ST	Q13107	USP4	P31749	AKT1	T242	S248C	248	Missense	distal	6	no	12.173	11.970	EPSD	ICGC;COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	Q13107	USP4	P31749	AKT1	T242	R239I	239	Missense	distal	-3	no	12.173	5.092	EPSD	ICGC	7.780	Loss
AGC_Akt_AKT1_ST	Q13107	USP4	P31749	AKT1	T242	T243N	243	Missense	proximal	1	no	12.173	11.891	EPSD	ICGC	7.780	Down-regulation
AGC_Akt_AKT1_ST	Q13107	USP4	P31749	AKT1	T242	P245T	245	Missense	distal	3	no	12.173	12.254	EPSD	ICGC;COSMIC	7.780	Up-regulation
AGC_Akt_AKT1_ST	Q13107	USP4	P31749	AKT1	S244	S248C	248	Missense	distal	4	no	10.240	10.584	EPSD	ICGC;COSMIC	7.780	Up-regulation
AGC_Akt_AKT1_ST	Q13107	USP4	P31749	AKT1	S244	R239I	239	Missense	distal	-5	no	10.240	5.672	EPSD	ICGC	7.780	Loss
AGC_Akt_AKT1_ST	Q13107	USP4	P31749	AKT1	S244	T243N	243	Missense	proximal	-1	no	10.240	10.216	EPSD	ICGC	7.780	Down-regulation
AGC_Akt_AKT1_ST	Q13107	USP4	P31749	AKT1	S244	P245T	245	Missense	proximal	1	no	10.240	10.588	EPSD	ICGC;COSMIC	7.780	Up-regulation
AGC_Akt_AKT1_ST	Q13107	USP4	P31749	AKT1	S248	S248C	248	Missense	central	0	yes	8.144	0.000	EPSD	ICGC;COSMIC	7.780	Loss
AGC_Akt_AKT1_ST	Q13107	USP4	P31749	AKT1	S248	T243N	243	Missense	distal	-5	no	8.144	7.390	EPSD	ICGC	7.780	Loss
AGC_Akt_AKT1_ST	Q13107	USP4	P31749	AKT1	S248	P245T	245	Missense	distal	-3	no	8.144	7.763	EPSD	ICGC;COSMIC	7.780	Loss
AGC_Akt_AKT1_ST	Q13107	USP4	P31749	AKT1	S445	R440Q	440	Missense	distal	-5	no	14.403	10.176	PhosphoSitePlus	ICGC;COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	P03372	ESR1	P31749	AKT1	S154	S154L	154	Missense	central	0	yes	11.303	0.000	EPSD	ICGC	7.780	Loss
AGC_Akt_AKT1_ST	P03372	ESR1	P31749	AKT1	S154	R158H	158	Missense	distal	4	no	11.303	11.487	EPSD	ICGC;COSMIC;CCLE	7.780	Up-regulation
AGC_Akt_AKT1_ST	P03372	ESR1	P31749	AKT1	S154	N153K	153	Missense	proximal	-1	no	11.303	11.327	EPSD	ICGC	7.780	Up-regulation
AGC_Akt_AKT1_ST	P03372	ESR1	P31749	AKT1	S154	P147L	147	Missense	distal	-7	no	11.303	11.263	EPSD	ICGC;COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	P03372	ESR1	P31749	AKT1	S167	E163Q	163	Missense	distal	-4	no	16.129	16.106	PhosphoSitePlus;EPSD	ICGC;COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	P03372	ESR1	P31749	AKT1	S236	Q238R	238	Missense	proximal	2	no	13.602	13.719	EPSD	ICGC	7.780	Up-regulation
AGC_Akt_AKT1_ST	P03372	ESR1	P31749	AKT1	S236	L242I	242	Missense	distal	6	no	13.602	13.541	EPSD	ICGC	7.780	Down-regulation
AGC_Akt_AKT1_ST	P03372	ESR1	P31749	AKT1	S236	R233M	233	Missense	distal	-3	no	13.602	6.096	EPSD	ICGC;COSMIC	7.780	Loss
AGC_Akt_AKT1_ST	P03372	ESR1	P31749	AKT1	S305	K302T	302	Missense	distal	-3	no	12.276	9.774	EPSD;PhosphoSitePlus	ICGC;COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	P03372	ESR1	P31749	AKT1	S305	R300L	300	Missense	distal	-5	no	12.276	8.149	EPSD;PhosphoSitePlus	ICGC;COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	P03372	ESR1	P31749	AKT1	S305	R300S	300	Missense	distal	-5	no	12.276	7.805	EPSD;PhosphoSitePlus	ICGC;COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	P03372	ESR1	P31749	AKT1	S305	R300H	300	Missense	distal	-5	no	12.276	9.181	EPSD;PhosphoSitePlus	ICGC;COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	Q12778	FOXO1	P31749	AKT1	S22	P28L	28	Missense	distal	6	no	10.495	10.485	EPSD	ICGC;COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	Q12778	FOXO1	P31749	AKT1	S22	T24A	24	Missense	proximal	2	no	10.495	10.193	EPSD	ICGC;COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	Q12778	FOXO1	P31749	AKT1	S22	R19Q	19	Missense	distal	-3	no	10.495	3.283	EPSD	ICGC;COSMIC	7.780	Loss
AGC_Akt_AKT1_ST	Q12778	FOXO1	P31749	AKT1	S22	T24I	24	Missense	proximal	2	no	10.495	9.913	EPSD	ICGC;COSMIC;CCLE	7.780	Down-regulation
AGC_Akt_AKT1_ST	Q12778	FOXO1	P31749	AKT1	S22	P26S	26	Missense	distal	4	no	10.495	10.339	EPSD	ICGC;COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	Q12778	FOXO1	P31749	AKT1	S22	R21C	21	Missense	proximal	-1	no	10.495	10.424	EPSD	ICGC;COSMIC;CCLE	7.780	Down-regulation
AGC_Akt_AKT1_ST	Q12778	FOXO1	P31749	AKT1	S22	R21H	21	Missense	proximal	-1	no	10.495	10.450	EPSD	ICGC;COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	Q12778	FOXO1	P31749	AKT1	S22	R21P	21	Missense	proximal	-1	no	10.495	10.455	EPSD	ICGC;COSMIC;CCLE	7.780	Down-regulation
AGC_Akt_AKT1_ST	Q12778	FOXO1	P31749	AKT1	S22	R19W	19	Missense	distal	-3	no	10.495	1.554	EPSD	ICGC;COSMIC;CCLE	7.780	Loss
AGC_Akt_AKT1_ST	Q12778	FOXO1	P31749	AKT1	S22	S22P	22	Missense	central	0	yes	10.495	0.000	EPSD	ICGC;COSMIC;CCLE	7.780	Loss
AGC_Akt_AKT1_ST	Q12778	FOXO1	P31749	AKT1	T24	P28L	28	Missense	distal	4	no	14.694	14.726	EPSD;PhosphoSitePlus	ICGC;COSMIC	7.780	Up-regulation
AGC_Akt_AKT1_ST	Q12778	FOXO1	P31749	AKT1	T24	S22T	22	Missense	proximal	-2	no	14.694	14.627	EPSD;PhosphoSitePlus	ICGC	7.780	Down-regulation
AGC_Akt_AKT1_ST	Q12778	FOXO1	P31749	AKT1	T24	T24A	24	Missense	central	0	yes	14.694	0.000	EPSD;PhosphoSitePlus	ICGC;COSMIC	7.780	Loss
AGC_Akt_AKT1_ST	Q12778	FOXO1	P31749	AKT1	T24	R19Q	19	Missense	distal	-5	no	14.694	10.466	EPSD;PhosphoSitePlus	ICGC;COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	Q12778	FOXO1	P31749	AKT1	T24	T24I	24	Missense	central	0	yes	14.694	0.000	EPSD;PhosphoSitePlus	ICGC;COSMIC;CCLE	7.780	Loss
AGC_Akt_AKT1_ST	Q12778	FOXO1	P31749	AKT1	T24	P26S	26	Missense	proximal	2	no	14.694	15.030	EPSD;PhosphoSitePlus	ICGC;COSMIC	7.780	Up-regulation
AGC_Akt_AKT1_ST	Q12778	FOXO1	P31749	AKT1	T24	R21C	21	Missense	distal	-3	no	14.694	8.520	EPSD;PhosphoSitePlus	ICGC;COSMIC;CCLE	7.780	Down-regulation
AGC_Akt_AKT1_ST	Q12778	FOXO1	P31749	AKT1	T24	R21H	21	Missense	distal	-3	no	14.694	9.995	EPSD;PhosphoSitePlus	ICGC;COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	Q12778	FOXO1	P31749	AKT1	T24	R21P	21	Missense	distal	-3	no	14.694	8.054	EPSD;PhosphoSitePlus	ICGC;COSMIC;CCLE	7.780	Down-regulation
AGC_Akt_AKT1_ST	Q12778	FOXO1	P31749	AKT1	T24	R19W	19	Missense	distal	-5	no	14.694	9.174	EPSD;PhosphoSitePlus	ICGC;COSMIC;CCLE	7.780	Down-regulation
AGC_Akt_AKT1_ST	Q12778	FOXO1	P31749	AKT1	T24	S22P	22	Missense	proximal	-2	no	14.694	13.870	EPSD;PhosphoSitePlus	ICGC;COSMIC;CCLE	7.780	Down-regulation
AGC_Akt_AKT1_ST	Q12778	FOXO1	P31749	AKT1	S256	D258E	258	Missense	proximal	2	no	16.241	16.651	EPSD;PhosphoSitePlus	ICGC	7.780	Up-regulation
AGC_Akt_AKT1_ST	Q12778	FOXO1	P31749	AKT1	S276	Q281K	281	Missense	distal	5	no	8.877	8.922	EPSD	ICGC;COSMIC	7.780	Up-regulation
AGC_Akt_AKT1_ST	Q12778	FOXO1	P31749	AKT1	S319	G326V	326	Missense	distal	7	no	17.079	17.097	PhosphoSitePlus;EPSD	ICGC;COSMIC	7.780	Up-regulation
AGC_Akt_AKT1_ST	Q12778	FOXO1	P31749	AKT1	S468	L465F	465	Missense	distal	-3	no	6.490	7.890	EPSD	ICGC;COSMIC	7.780	Gain
AGC_Akt_AKT1_ST	Q12778	FOXO1	P31749	AKT1	T648	S651R	651	Missense	distal	3	no	8.077	8.060	EPSD	ICGC	7.780	Down-regulation
AGC_Akt_AKT1_ST	Q12778	FOXO1	P31749	AKT1	T648	T649A	649	Missense	proximal	1	no	8.077	7.810	EPSD	ICGC	7.780	Down-regulation
AGC_Akt_AKT1_ST	Q12778	FOXO1	P31749	AKT1	S651	S651R	651	Missense	central	0	yes	9.253	0.000	EPSD	ICGC	7.780	Loss
AGC_Akt_AKT1_ST	Q12778	FOXO1	P31749	AKT1	S651	T649A	649	Missense	proximal	-2	no	9.253	8.867	EPSD	ICGC	7.780	Down-regulation
AGC_Akt_AKT1_ST	Q12778	FOXO1	P31749	AKT1	S654	S651R	651	Missense	distal	-3	no	4.700	12.476	EPSD	ICGC	7.780	Gain
AGC_Akt_AKT1_ST	P24941	CDK2	P31749	AKT1	T39	D38V	38	Missense	proximal	-1	no	11.312	11.325	PhosphoSitePlus	ICGC;COSMIC	7.780	Up-regulation
AGC_Akt_AKT1_ST	P24941	CDK2	P31749	AKT1	T39	T39M	39	Missense	central	0	yes	11.312	0.000	PhosphoSitePlus	ICGC	7.780	Loss
AGC_Akt_AKT1_ST	P24941	CDK2	P31749	AKT1	T41	D38V	38	Missense	distal	-3	no	8.353	7.439	EPSD	ICGC;COSMIC	7.780	Loss
AGC_Akt_AKT1_ST	P24941	CDK2	P31749	AKT1	T41	T39M	39	Missense	proximal	-2	no	8.353	7.580	EPSD	ICGC	7.780	Loss
AGC_Akt_AKT1_ST	P24941	CDK2	P31749	AKT1	T160	R157W	157	Missense	distal	-3	no	10.875	1.934	EPSD	ICGC;COSMIC	7.780	Loss
AGC_Akt_AKT1_ST	P24941	CDK2	P31749	AKT1	T160	R157L	157	Missense	distal	-3	no	10.875	3.881	EPSD	ICGC;COSMIC	7.780	Loss
AGC_Akt_AKT1_ST	P55316	FOXG1	P31749	AKT1	S277	R275L	275	Missense	proximal	-2	no	13.906	13.238	EPSD	ICGC	7.780	Down-regulation
AGC_Akt_AKT1_ST	P55316	FOXG1	P31749	AKT1	S277	L284P	284	Missense	distal	7	no	13.906	13.914	EPSD	ICGC	7.780	Up-regulation
AGC_Akt_AKT1_ST	P55316	FOXG1	P31749	AKT1	T278	R275L	275	Missense	distal	-3	no	12.506	5.513	EPSD	ICGC	7.780	Loss
AGC_Akt_AKT1_ST	P55316	FOXG1	P31749	AKT1	T278	L284P	284	Missense	distal	6	no	12.506	12.516	EPSD	ICGC	7.780	Up-regulation
AGC_Akt_AKT1_ST	P55316	FOXG1	P31749	AKT1	T279	R275L	275	Missense	distal	-4	no	15.575	14.365	PhosphoSitePlus	ICGC	7.780	Down-regulation
AGC_Akt_AKT1_ST	P55316	FOXG1	P31749	AKT1	T279	L284P	284	Missense	distal	5	no	15.575	15.588	PhosphoSitePlus	ICGC	7.780	Up-regulation
AGC_Akt_AKT1_ST	P55316	FOXG1	P31749	AKT1	S280	R275L	275	Missense	distal	-5	no	9.778	5.652	EPSD	ICGC	7.780	Loss
AGC_Akt_AKT1_ST	P55316	FOXG1	P31749	AKT1	S280	L284P	284	Missense	distal	4	no	9.778	9.746	EPSD	ICGC	7.780	Down-regulation
AGC_Akt_AKT1_ST	P15056	BRAF	P31749	AKT1	T244	R239Q	239	Missense	distal	-5	no	8.175	3.947	EPSD	ICGC;COSMIC	7.780	Loss
AGC_Akt_AKT1_ST	P15056	BRAF	P31749	AKT1	T244	D249Y	249	Missense	distal	5	no	8.175	8.206	EPSD	ICGC;COSMIC	7.780	Up-regulation
AGC_Akt_AKT1_ST	P15056	BRAF	P31749	AKT1	S363	Q359K	359	Missense	distal	-4	no	12.988	13.595	EPSD	ICGC	7.780	Up-regulation
AGC_Akt_AKT1_ST	P15056	BRAF	P31749	AKT1	S363	S363F	363	Missense	central	0	yes	12.988	0.000	EPSD	ICGC;COSMIC	7.780	Loss
AGC_Akt_AKT1_ST	P15056	BRAF	P31749	AKT1	S363	P367L	367	Missense	distal	4	no	12.988	13.020	EPSD	ICGC;COSMIC	7.780	Up-regulation
AGC_Akt_AKT1_ST	P15056	BRAF	P31749	AKT1	S363	Q359R	359	Missense	distal	-4	no	12.988	13.609	EPSD	ICGC;COSMIC	7.780	Up-regulation
AGC_Akt_AKT1_ST	P15056	BRAF	P31749	AKT1	S364	Q359K	359	Missense	distal	-5	no	7.137	8.967	EPSD	ICGC	7.780	Gain
AGC_Akt_AKT1_ST	P15056	BRAF	P31749	AKT1	S364	Q359R	359	Missense	distal	-5	no	7.137	11.364	EPSD	ICGC;COSMIC	7.780	Gain
AGC_Akt_AKT1_ST	P15056	BRAF	P31749	AKT1	S365	N372K	372	Missense	distal	7	no	16.893	16.928	PhosphoSitePlus;EPSD	ICGC	7.780	Up-regulation
AGC_Akt_AKT1_ST	P15056	BRAF	P31749	AKT1	S365	Q359K	359	Missense	distal	-6	no	16.893	16.963	PhosphoSitePlus;EPSD	ICGC	7.780	Up-regulation
AGC_Akt_AKT1_ST	P15056	BRAF	P31749	AKT1	S365	S363F	363	Missense	proximal	-2	no	16.893	16.026	PhosphoSitePlus;EPSD	ICGC;COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	P15056	BRAF	P31749	AKT1	S365	P367L	367	Missense	proximal	2	no	16.893	16.683	PhosphoSitePlus;EPSD	ICGC;COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	P15056	BRAF	P31749	AKT1	S365	Q359R	359	Missense	distal	-6	no	16.893	16.977	PhosphoSitePlus;EPSD	ICGC;COSMIC	7.780	Up-regulation
AGC_Akt_AKT1_ST	P15056	BRAF	P31749	AKT1	S394	R389H	389	Missense	distal	-5	no	9.120	6.025	EPSD	ICGC;COSMIC	7.780	Loss
AGC_Akt_AKT1_ST	P15056	BRAF	P31749	AKT1	S394	R389S	389	Missense	distal	-5	no	9.120	4.650	EPSD	ICGC	7.780	Loss
AGC_Akt_AKT1_ST	P15056	BRAF	P31749	AKT1	S429	S429Y	429	Missense	central	0	yes	17.215	0.000	EPSD;PhosphoSitePlus	ICGC	7.780	Loss
AGC_Akt_AKT1_ST	P15056	BRAF	P31749	AKT1	S429	Q423H	423	Missense	distal	-6	no	17.215	17.181	EPSD;PhosphoSitePlus	ICGC;COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	P15056	BRAF	P31749	AKT1	S429	S428T	428	Missense	proximal	-1	no	17.215	17.221	EPSD;PhosphoSitePlus	ICGC;COSMIC	7.780	Up-regulation
AGC_Akt_AKT1_ST	P15056	BRAF	P31749	AKT1	S430	S429Y	429	Missense	proximal	-1	no	8.153	8.127	EPSD	ICGC	7.780	Down-regulation
AGC_Akt_AKT1_ST	P15056	BRAF	P31749	AKT1	S430	Q423H	423	Missense	distal	-7	no	8.153	8.046	EPSD	ICGC;COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	P15056	BRAF	P31749	AKT1	S430	S428T	428	Missense	proximal	-2	no	8.153	8.087	EPSD	ICGC;COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	P15056	BRAF	P31749	AKT1	S431	S429Y	429	Missense	proximal	-2	no	9.847	8.925	EPSD	ICGC	7.780	Down-regulation
AGC_Akt_AKT1_ST	P15056	BRAF	P31749	AKT1	S431	M438I	438	Missense	distal	7	no	9.847	9.809	EPSD	ICGC;COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	P15056	BRAF	P31749	AKT1	S431	S428T	428	Missense	distal	-3	no	9.847	10.602	EPSD	ICGC;COSMIC	7.780	Up-regulation
AGC_Akt_AKT1_ST	P15056	BRAF	P31749	AKT1	T440	R444Q	444	Missense	distal	4	no	13.648	13.771	EPSD	ICGC;COSMIC	7.780	Up-regulation
AGC_Akt_AKT1_ST	P15056	BRAF	P31749	AKT1	T440	R444W	444	Missense	distal	4	no	13.648	13.895	EPSD	ICGC;COSMIC	7.780	Up-regulation
AGC_Akt_AKT1_ST	P15056	BRAF	P31749	AKT1	T440	T440K	440	Missense	central	0	yes	13.648	0.000	EPSD	ICGC	7.780	Loss
AGC_Akt_AKT1_ST	P15056	BRAF	P31749	AKT1	T440	L441I	441	Missense	proximal	1	no	13.648	13.301	EPSD	ICGC;COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	P15056	BRAF	P31749	AKT1	T440	S446L	446	Missense	distal	6	no	13.648	13.545	EPSD	ICGC;COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	P15056	BRAF	P31749	AKT1	T440	M438I	438	Missense	proximal	-2	no	13.648	13.247	EPSD	ICGC;COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	P15056	BRAF	P31749	AKT1	S446	R444Q	444	Missense	proximal	-2	no	11.248	10.736	EPSD	ICGC;COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	P15056	BRAF	P31749	AKT1	S446	R444W	444	Missense	proximal	-2	no	11.248	9.994	EPSD	ICGC;COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	P15056	BRAF	P31749	AKT1	S446	T440K	440	Missense	distal	-6	no	11.248	11.238	EPSD	ICGC	7.780	Down-regulation
AGC_Akt_AKT1_ST	P15056	BRAF	P31749	AKT1	S446	L441I	441	Missense	distal	-5	no	11.248	10.807	EPSD	ICGC;COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	P15056	BRAF	P31749	AKT1	S446	E451D	451	Missense	distal	5	no	11.248	11.206	EPSD	ICGC;COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	P15056	BRAF	P31749	AKT1	S446	S446L	446	Missense	central	0	yes	11.248	0.000	EPSD	ICGC;COSMIC	7.780	Loss
AGC_Akt_AKT1_ST	P15056	BRAF	P31749	AKT1	S447	R444Q	444	Missense	distal	-3	no	9.898	2.687	EPSD	ICGC;COSMIC	7.780	Loss
AGC_Akt_AKT1_ST	P15056	BRAF	P31749	AKT1	S447	R444W	444	Missense	distal	-3	no	9.898	0.958	EPSD	ICGC;COSMIC	7.780	Loss
AGC_Akt_AKT1_ST	P15056	BRAF	P31749	AKT1	S447	T440K	440	Missense	distal	-7	no	9.898	9.891	EPSD	ICGC	7.780	Down-regulation
AGC_Akt_AKT1_ST	P15056	BRAF	P31749	AKT1	S447	L441I	441	Missense	distal	-6	no	9.898	9.829	EPSD	ICGC;COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	P15056	BRAF	P31749	AKT1	S447	E451D	451	Missense	distal	4	no	9.898	10.044	EPSD	ICGC;COSMIC	7.780	Up-regulation
AGC_Akt_AKT1_ST	P15056	BRAF	P31749	AKT1	S447	S446L	446	Missense	proximal	-1	no	9.898	9.870	EPSD	ICGC;COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	P15056	BRAF	P31749	AKT1	S465	V471F	471	Missense	distal	6	no	11.227	11.221	EPSD	ICGC;COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	P15056	BRAF	P31749	AKT1	S465	Q461K	461	Missense	distal	-4	no	11.227	11.834	EPSD	ICGC	7.780	Up-regulation
AGC_Akt_AKT1_ST	P15056	BRAF	P31749	AKT1	S465	G466R	466	Missense	proximal	1	no	11.227	11.676	EPSD	ICGC;COSMIC	7.780	Up-regulation
AGC_Akt_AKT1_ST	P15056	BRAF	P31749	AKT1	S465	S465Y	465	Missense	central	0	yes	11.227	0.000	EPSD	ICGC	7.780	Loss
AGC_Akt_AKT1_ST	P15056	BRAF	P31749	AKT1	S465	R462K	462	Missense	distal	-3	no	11.227	6.706	EPSD	ICGC;COSMIC	7.780	Loss
AGC_Akt_AKT1_ST	P15056	BRAF	P31749	AKT1	S467	V471F	471	Missense	distal	4	no	9.345	9.361	EPSD	ICGC;COSMIC	7.780	Up-regulation
AGC_Akt_AKT1_ST	P15056	BRAF	P31749	AKT1	S467	Q461K	461	Missense	distal	-6	no	9.345	9.415	EPSD	ICGC	7.780	Up-regulation
AGC_Akt_AKT1_ST	P15056	BRAF	P31749	AKT1	S467	G466R	466	Missense	proximal	-1	no	9.345	9.385	EPSD	ICGC;COSMIC	7.780	Up-regulation
AGC_Akt_AKT1_ST	P15056	BRAF	P31749	AKT1	S467	S465Y	465	Missense	proximal	-2	no	9.345	8.423	EPSD	ICGC	7.780	Down-regulation
AGC_Akt_AKT1_ST	P15056	BRAF	P31749	AKT1	S467	R462K	462	Missense	distal	-5	no	9.345	6.948	EPSD	ICGC;COSMIC	7.780	Loss
AGC_Akt_AKT1_ST	P15056	BRAF	P31749	AKT1	S605	V600R	600	Missense	distal	-5	no	5.237	9.552	EPSD	ICGC;COSMIC	7.780	Gain
AGC_Akt_AKT1_ST	P15056	BRAF	P31749	AKT1	S729	R726H	726	Missense	distal	-3	no	11.274	6.575	EPSD	ICGC;COSMIC	7.780	Loss
AGC_Akt_AKT1_ST	P15056	BRAF	P31749	AKT1	S729	I724M	724	Missense	distal	-5	no	11.274	11.319	EPSD	ICGC	7.780	Up-regulation
AGC_Akt_AKT1_ST	P15056	BRAF	P31749	AKT1	S729	E730D	730	Missense	proximal	1	no	11.274	11.157	EPSD	ICGC	7.780	Down-regulation
AGC_Akt_AKT1_ST	P15056	BRAF	P31749	AKT1	S729	S727G	727	Missense	proximal	-2	no	11.274	10.579	EPSD	ICGC;COSMIC;GDSC;CCLE	7.780	Down-regulation
AGC_Akt_AKT1_ST	P15056	BRAF	P31749	AKT1	T740	T740K	740	Missense	central	0	yes	8.293	0.000	EPSD	ICGC;COSMIC	7.780	Loss
AGC_Akt_AKT1_ST	Q9Y2V2	CARHSP1	P31749	AKT1	S17	G19W	19	Missense	proximal	2	no	8.770	8.475	EPSD	ICGC;COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	Q9Y2V2	CARHSP1	P31749	AKT1	T50	S52L	52	Missense	proximal	2	no	13.027	12.482	EPSD	ICGC;COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	Q9Y2V2	CARHSP1	P31749	AKT1	T50	P44H	44	Missense	distal	-6	no	13.027	13.007	EPSD	ICGC;COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	Q9Y2V2	CARHSP1	P31749	AKT1	S52	S52L	52	Missense	central	0	yes	17.128	0.000	PhosphoSitePlus	ICGC;COSMIC	7.780	Loss
AGC_Akt_AKT1_ST	Q9Y2V2	CARHSP1	P31749	AKT1	T54	S52L	52	Missense	proximal	-2	no	12.372	11.515	EPSD	ICGC;COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	Q9Y2V2	CARHSP1	P31749	AKT1	T139	W140L	140	Missense	proximal	1	no	8.510	8.756	EPSD	ICGC;COSMIC	7.780	Up-regulation
AGC_Akt_AKT1_ST	Q9Y2V2	CARHSP1	P31749	AKT1	S141	W140L	140	Missense	proximal	-1	no	8.201	8.223	EPSD	ICGC;COSMIC	7.780	Up-regulation
AGC_Akt_AKT1_ST	O14745	SLC9A3R1	P31749	AKT1	T156	R151L	151	Missense	distal	-5	no	14.210	10.084	PhosphoSitePlus	ICGC	7.780	Down-regulation
AGC_Akt_AKT1_ST	O14745	SLC9A3R1	P31749	AKT1	T156	P152S	152	Missense	distal	-4	no	14.210	14.947	PhosphoSitePlus	ICGC;COSMIC	7.780	Up-regulation
AGC_Akt_AKT1_ST	O14745	SLC9A3R1	P31749	AKT1	S340	D347N	347	Missense	distal	7	no	10.058	10.099	EPSD	ICGC;COSMIC	7.780	Up-regulation
AGC_Akt_AKT1_ST	O14745	SLC9A3R1	P31749	AKT1	S340	R338H	338	Missense	proximal	-2	no	10.058	9.197	EPSD	ICGC;COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	O14745	SLC9A3R1	P31749	AKT1	S356	E353K	353	Missense	distal	-3	no	7.552	9.603	EPSD	ICGC;COSMIC	7.780	Gain
AGC_Akt_AKT1_ST	Q9P0N9	TBC1D7	P31749	AKT1	S124	P129Q	129	Missense	distal	5	no	12.487	12.497	PhosphoSitePlus	ICGC	7.780	Up-regulation
AGC_Akt_AKT1_ST	Q05195	MXD1	P31749	AKT1	S145	S145C	145	Missense	central	0	yes	14.110	0.000	PhosphoSitePlus	ICGC;COSMIC	7.780	Loss
AGC_Akt_AKT1_ST	P62753	RPS6	P31749	AKT1	T34	A33D	33	Missense	proximal	-1	no	11.725	11.697	EPSD	ICGC	7.780	Down-regulation
AGC_Akt_AKT1_ST	P62753	RPS6	P31749	AKT1	T34	R31C	31	Missense	distal	-3	no	11.725	5.551	EPSD	ICGC	7.780	Loss
AGC_Akt_AKT1_ST	P62753	RPS6	P31749	AKT1	S235	A229S	229	Missense	distal	-6	no	16.340	16.395	EPSD	ICGC;COSMIC	7.780	Up-regulation
AGC_Akt_AKT1_ST	P62753	RPS6	P31749	AKT1	S235	A229V	229	Missense	distal	-6	no	16.340	16.320	EPSD	ICGC;COSMIC;GDSC;CCLE	7.780	Down-regulation
AGC_Akt_AKT1_ST	P62753	RPS6	P31749	AKT1	S236	A229S	229	Missense	distal	-7	no	18.528	18.678	PhosphoSitePlus	ICGC;COSMIC	7.780	Up-regulation
AGC_Akt_AKT1_ST	P62753	RPS6	P31749	AKT1	S236	A229V	229	Missense	distal	-7	no	18.528	18.400	PhosphoSitePlus	ICGC;COSMIC;GDSC;CCLE	7.780	Down-regulation
AGC_Akt_AKT1_ST	Q14457	BECN1	P31749	AKT1	S10	Q13R	13	Missense	distal	3	no	8.163	8.219	EPSD	ICGC;COSMIC	7.780	Up-regulation
AGC_Akt_AKT1_ST	Q14457	BECN1	P31749	AKT1	S10	M12I	12	Missense	proximal	2	no	8.163	7.923	EPSD	ICGC;COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	Q14457	BECN1	P31749	AKT1	S10	T6M	6	Missense	distal	-4	no	8.163	7.198	EPSD	ICGC;COSMIC	7.780	Loss
AGC_Akt_AKT1_ST	Q14457	BECN1	P31749	AKT1	S90	P85Q	85	Missense	distal	-5	no	10.581	10.364	EPSD	ICGC	7.780	Down-regulation
AGC_Akt_AKT1_ST	Q14457	BECN1	P31749	AKT1	T119	S113R	113	Missense	distal	-6	no	9.392	9.426	EPSD	ICGC	7.780	Up-regulation
AGC_Akt_AKT1_ST	Q14457	BECN1	P31749	AKT1	T119	L122I	122	Missense	distal	3	no	9.392	9.358	EPSD	ICGC;COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	Q14457	BECN1	P31749	AKT1	S234	Q240K	240	Missense	distal	6	no	10.326	10.408	EPSD	ICGC	7.780	Up-regulation
AGC_Akt_AKT1_ST	Q14457	BECN1	P31749	AKT1	S234	Q230H	230	Missense	distal	-4	no	10.326	9.888	EPSD	ICGC;COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	Q14457	BECN1	P31749	AKT1	S295	P294H	294	Missense	proximal	-1	no	11.785	11.779	PhosphoSitePlus	ICGC	7.780	Down-regulation
AGC_Akt_AKT1_ST	Q14457	BECN1	P31749	AKT1	S295	P297T	297	Missense	proximal	2	no	11.785	12.046	PhosphoSitePlus	ICGC	7.780	Up-regulation
AGC_Akt_AKT1_ST	Q14457	BECN1	P31749	AKT1	S337	G334R	334	Missense	distal	-3	no	5.596	12.352	EPSD	ICGC;COSMIC	7.780	Gain
AGC_Akt_AKT1_ST	Q9Y5S9	RBM8A	P31749	AKT1	S166	R164T	164	Missense	proximal	-2	no	15.380	15.502	EPSD	ICGC	7.780	Up-regulation
AGC_Akt_AKT1_ST	Q9Y5S9	RBM8A	P31749	AKT1	S166	R167S	167	Missense	proximal	1	no	15.380	15.235	EPSD	ICGC;COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	Q9Y5S9	RBM8A	P31749	AKT1	S168	R164T	164	Missense	distal	-4	no	18.571	18.541	PhosphoSitePlus	ICGC	7.780	Down-regulation
AGC_Akt_AKT1_ST	Q9Y5S9	RBM8A	P31749	AKT1	S168	R167S	167	Missense	proximal	-1	no	18.571	18.560	PhosphoSitePlus	ICGC;COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	P67809	YBX1	P31749	AKT1	T80	K81E	81	Missense	proximal	1	no	9.901	9.738	EPSD	ICGC;COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	P67809	YBX1	P31749	AKT1	T80	V84L	84	Missense	distal	4	no	9.901	9.910	EPSD	ICGC;COSMIC	7.780	Up-regulation
AGC_Akt_AKT1_ST	P67809	YBX1	P31749	AKT1	T80	D79Y	79	Missense	proximal	-1	no	9.901	9.923	EPSD	ICGC	7.780	Up-regulation
AGC_Akt_AKT1_ST	P67809	YBX1	P31749	AKT1	S102	D105G	105	Missense	distal	3	no	8.722	8.743	PhosphoSitePlus	ICGC;COSMIC	7.780	Up-regulation
AGC_Akt_AKT1_ST	P67809	YBX1	P31749	AKT1	S209	R205Q	205	Missense	distal	-4	no	9.316	8.695	EPSD	ICGC	7.780	Down-regulation
AGC_Akt_AKT1_ST	O14757	CHEK1	P31749	AKT1	S280	P276S	276	Missense	distal	-4	no	12.979	13.715	PhosphoSitePlus	ICGC	7.780	Up-regulation
AGC_Akt_AKT1_ST	O14757	CHEK1	P31749	AKT1	S280	V283L	283	Missense	distal	3	no	12.979	12.971	PhosphoSitePlus	ICGC	7.780	Down-regulation
AGC_Akt_AKT1_ST	O14757	CHEK1	P31749	AKT1	T382	R376I	376	Missense	distal	-6	no	10.085	9.930	EPSD	ICGC	7.780	Down-regulation
AGC_Akt_AKT1_ST	O14757	CHEK1	P31749	AKT1	T382	R379L	379	Missense	distal	-3	no	10.085	3.091	EPSD	ICGC	7.780	Loss
AGC_Akt_AKT1_ST	O14757	CHEK1	P31749	AKT1	T382	A386S	386	Missense	distal	4	no	10.085	9.961	EPSD	ICGC;COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	O14757	CHEK1	P31749	AKT1	T382	M377V	377	Missense	distal	-5	no	10.085	10.293	EPSD	ICGC;COSMIC	7.780	Up-regulation
AGC_Akt_AKT1_ST	Q13131	PRKAA1	P31749	AKT1	S5	W7L	7	Missense	proximal	2	no	12.347	12.428	EPSD	ICGC;COSMIC	7.780	Up-regulation
AGC_Akt_AKT1_ST	Q13131	PRKAA1	P31749	AKT1	S5	R2C	2	Missense	distal	-3	no	12.347	6.173	EPSD	ICGC;COSMIC	7.780	Loss
AGC_Akt_AKT1_ST	Q13131	PRKAA1	P31749	AKT1	S6	W7L	7	Missense	proximal	1	no	13.273	13.519	EPSD	ICGC;COSMIC	7.780	Up-regulation
AGC_Akt_AKT1_ST	Q13131	PRKAA1	P31749	AKT1	S6	R2C	2	Missense	distal	-4	no	13.273	11.594	EPSD	ICGC;COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	Q13131	PRKAA1	P31749	AKT1	S65	R64Q	64	Missense	proximal	-1	no	11.607	11.575	EPSD	ICGC;COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	Q13131	PRKAA1	P31749	AKT1	S65	V69A	69	Missense	distal	4	no	11.607	11.552	EPSD	ICGC	7.780	Down-regulation
AGC_Akt_AKT1_ST	Q13131	PRKAA1	P31749	AKT1	S187	N189S	189	Missense	proximal	2	no	8.633	8.902	EPSD	ICGC;COSMIC;CCLE	7.780	Up-regulation
AGC_Akt_AKT1_ST	Q13131	PRKAA1	P31749	AKT1	S187	T183K	183	Missense	distal	-4	no	8.633	8.649	EPSD	ICGC	7.780	Up-regulation
AGC_Akt_AKT1_ST	Q13131	PRKAA1	P31749	AKT1	S496	S498C	498	Missense	proximal	2	no	13.385	12.560	PhosphoSitePlus	ICGC;COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	Q13131	PRKAA1	P31749	AKT1	S496	R501P	501	Missense	distal	5	no	13.385	13.324	PhosphoSitePlus	ICGC;COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	Q13131	PRKAA1	P31749	AKT1	S496	C503Y	503	Missense	distal	7	no	13.385	13.464	PhosphoSitePlus	ICGC	7.780	Up-regulation
AGC_Akt_AKT1_ST	Q13131	PRKAA1	P31749	AKT1	S496	Y500C	500	Missense	distal	4	no	13.385	13.594	PhosphoSitePlus	ICGC;COSMIC	7.780	Up-regulation
AGC_Akt_AKT1_ST	Q13131	PRKAA1	P31749	AKT1	S498	S498C	498	Missense	central	0	yes	9.782	0.000	EPSD	ICGC;COSMIC	7.780	Loss
AGC_Akt_AKT1_ST	Q13131	PRKAA1	P31749	AKT1	S498	R501P	501	Missense	distal	3	no	9.782	9.717	EPSD	ICGC;COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	Q13131	PRKAA1	P31749	AKT1	S498	C503Y	503	Missense	distal	5	no	9.782	9.857	EPSD	ICGC	7.780	Up-regulation
AGC_Akt_AKT1_ST	Q13131	PRKAA1	P31749	AKT1	S498	Y500C	500	Missense	proximal	2	no	9.782	9.330	EPSD	ICGC;COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	Q13131	PRKAA1	P31749	AKT1	S498	R505M	505	Missense	distal	7	no	9.782	9.716	EPSD	ICGC	7.780	Down-regulation
AGC_Akt_AKT1_ST	Q13131	PRKAA1	P31749	AKT1	S506	R501P	501	Missense	distal	-5	no	9.651	5.641	EPSD	ICGC;COSMIC	7.780	Loss
AGC_Akt_AKT1_ST	Q13131	PRKAA1	P31749	AKT1	S506	C503Y	503	Missense	distal	-3	no	9.651	8.236	EPSD	ICGC	7.780	Down-regulation
AGC_Akt_AKT1_ST	Q13131	PRKAA1	P31749	AKT1	S506	Y500C	500	Missense	distal	-6	no	9.651	9.564	EPSD	ICGC;COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	Q13131	PRKAA1	P31749	AKT1	S506	R505M	505	Missense	proximal	-1	no	9.651	9.612	EPSD	ICGC	7.780	Down-regulation
AGC_Akt_AKT1_ST	Q13131	PRKAA1	P31749	AKT1	S508	R501P	501	Missense	distal	-7	no	11.164	10.914	EPSD	ICGC;COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	Q13131	PRKAA1	P31749	AKT1	S508	C503Y	503	Missense	distal	-5	no	11.164	10.633	EPSD	ICGC	7.780	Down-regulation
AGC_Akt_AKT1_ST	Q13131	PRKAA1	P31749	AKT1	S508	R505M	505	Missense	distal	-3	no	11.164	3.659	EPSD	ICGC	7.780	Loss
AGC_Akt_AKT1_ST	Q13131	PRKAA1	P31749	AKT1	S541	E545D	545	Missense	distal	4	no	11.160	11.306	EPSD	ICGC	7.780	Up-regulation
AGC_Akt_AKT1_ST	Q13131	PRKAA1	P31749	AKT1	S541	T543K	543	Missense	proximal	2	no	11.160	11.251	EPSD	ICGC;COSMIC	7.780	Up-regulation
AGC_Akt_AKT1_ST	Q13131	PRKAA1	P31749	AKT1	S541	E545A	545	Missense	distal	4	no	11.160	11.206	EPSD	ICGC;COSMIC	7.780	Up-regulation
AGC_Akt_AKT1_ST	Q13131	PRKAA1	P31749	AKT1	T543	E545D	545	Missense	proximal	2	no	9.458	9.048	EPSD	ICGC	7.780	Down-regulation
AGC_Akt_AKT1_ST	Q13131	PRKAA1	P31749	AKT1	T543	C550S	550	Missense	distal	7	no	9.458	9.580	EPSD	ICGC;COSMIC	7.780	Up-regulation
AGC_Akt_AKT1_ST	Q13131	PRKAA1	P31749	AKT1	T543	T543K	543	Missense	central	0	yes	9.458	0.000	EPSD	ICGC;COSMIC	7.780	Loss
AGC_Akt_AKT1_ST	Q13131	PRKAA1	P31749	AKT1	T543	E545A	545	Missense	proximal	2	no	9.458	9.271	EPSD	ICGC;COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	Q9UQC2	GAB2	P31749	AKT1	S445	I439N	439	Missense	distal	-6	no	11.344	11.417	EPSD	ICGC;COSMIC	7.780	Up-regulation
AGC_Akt_AKT1_ST	P23769	GATA2	P31749	AKT1	S182	T176M	176	Missense	distal	-6	no	8.663	8.570	EPSD	ICGC;COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	P23769	GATA2	P31749	AKT1	S182	P175S	175	Missense	distal	-7	no	8.663	8.857	EPSD	ICGC	7.780	Up-regulation
AGC_Akt_AKT1_ST	P23769	GATA2	P31749	AKT1	S182	P183H	183	Missense	proximal	1	no	8.663	8.640	EPSD	ICGC;COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	P23769	GATA2	P31749	AKT1	S288	R287S	287	Missense	proximal	-1	no	12.407	12.396	EPSD	ICGC;COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	P23769	GATA2	P31749	AKT1	S288	R293L	293	Missense	distal	5	no	12.407	12.333	EPSD	ICGC;COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	P23769	GATA2	P31749	AKT1	S290	R287S	287	Missense	distal	-3	no	13.645	5.868	EPSD	ICGC;COSMIC	7.780	Loss
AGC_Akt_AKT1_ST	P23769	GATA2	P31749	AKT1	S290	R293L	293	Missense	distal	3	no	13.645	13.564	EPSD	ICGC;COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	P23769	GATA2	P31749	AKT1	S340	R337Q	337	Missense	distal	-3	no	10.890	3.679	EPSD	ICGC;COSMIC;GDSC;CCLE	7.780	Loss
AGC_Akt_AKT1_ST	P23769	GATA2	P31749	AKT1	S340	L339Q	339	Missense	proximal	-1	no	10.890	10.897	EPSD	ICGC;COSMIC	7.780	Up-regulation
AGC_Akt_AKT1_ST	P41002	CCNF	P31749	AKT1	T31	E37K	37	Missense	distal	6	no	13.093	13.163	EPSD;PhosphoSitePlus	ICGC;COSMIC	7.780	Up-regulation
AGC_Akt_AKT1_ST	P41002	CCNF	P31749	AKT1	S577	Q579K	579	Missense	proximal	2	no	18.054	18.360	PhosphoSitePlus;EPSD	ICGC;COSMIC	7.780	Up-regulation
AGC_Akt_AKT1_ST	Q05397	PTK2	P31749	AKT1	T24	R28S	28	Missense	distal	4	no	8.787	8.777	EPSD	ICGC	7.780	Down-regulation
AGC_Akt_AKT1_ST	Q05397	PTK2	P31749	AKT1	T24	R28C	28	Missense	distal	4	no	8.787	9.121	EPSD	ICGC;COSMIC	7.780	Up-regulation
AGC_Akt_AKT1_ST	Q05397	PTK2	P31749	AKT1	T24	S17Y	17	Missense	distal	-7	no	8.787	8.581	EPSD	ICGC;COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	Q05397	PTK2	P31749	AKT1	S239	N233K	233	Missense	distal	-6	no	10.719	10.786	EPSD	ICGC	7.780	Up-regulation
AGC_Akt_AKT1_ST	Q05397	PTK2	P31749	AKT1	S390	H387N	387	Missense	distal	-3	no	10.293	7.515	EPSD	ICGC	7.780	Loss
AGC_Akt_AKT1_ST	Q05397	PTK2	P31749	AKT1	S390	G383D	383	Missense	distal	-7	no	10.293	10.107	EPSD	ICGC	7.780	Down-regulation
AGC_Akt_AKT1_ST	Q05397	PTK2	P31749	AKT1	S390	V389I	389	Missense	proximal	-1	no	10.293	10.278	EPSD	ICGC;COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	Q05397	PTK2	P31749	AKT1	S517	L511F	511	Missense	distal	-6	no	12.096	12.072	EPSD	ICGC;COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	Q05397	PTK2	P31749	AKT1	S695	R690S	690	Missense	distal	-5	no	15.318	10.848	PhosphoSitePlus;EPSD	ICGC	7.780	Down-regulation
AGC_Akt_AKT1_ST	Q05397	PTK2	P31749	AKT1	S722	P723Q	723	Missense	proximal	1	no	9.370	9.375	EPSD	ICGC	7.780	Up-regulation
AGC_Akt_AKT1_ST	Q05397	PTK2	P31749	AKT1	S722	E727K	727	Missense	distal	5	no	9.370	9.404	EPSD	ICGC;COSMIC	7.780	Up-regulation
AGC_Akt_AKT1_ST	P54253	ATXN1	P31749	AKT1	T22	S26C	26	Missense	distal	4	no	8.868	9.213	EPSD	ICGC;COSMIC	7.780	Up-regulation
AGC_Akt_AKT1_ST	P54253	ATXN1	P31749	AKT1	T22	A21T	21	Missense	proximal	-1	no	8.868	8.895	EPSD	ICGC;COSMIC	7.780	Up-regulation
AGC_Akt_AKT1_ST	P54253	ATXN1	P31749	AKT1	T22	R17C	17	Missense	distal	-5	no	8.868	4.791	EPSD	ICGC	7.780	Loss
AGC_Akt_AKT1_ST	P54253	ATXN1	P31749	AKT1	S262	R259H	259	Missense	distal	-3	no	12.639	7.940	EPSD	ICGC;COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	P54253	ATXN1	P31749	AKT1	S262	A265D	265	Missense	distal	3	no	12.639	12.585	EPSD	ICGC	7.780	Down-regulation
AGC_Akt_AKT1_ST	P54253	ATXN1	P31749	AKT1	S312	S312N	312	Missense	central	0	yes	8.426	0.000	EPSD	ICGC;COSMIC	7.780	Loss
AGC_Akt_AKT1_ST	P54253	ATXN1	P31749	AKT1	S406	T409N	409	Missense	distal	3	no	12.949	12.894	EPSD	ICGC;COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	P54253	ATXN1	P31749	AKT1	S406	R403C	403	Missense	distal	-3	no	12.949	6.776	EPSD	ICGC;COSMIC	7.780	Loss
AGC_Akt_AKT1_ST	P54253	ATXN1	P31749	AKT1	S406	P407S	407	Missense	proximal	1	no	12.949	13.104	EPSD	ICGC	7.780	Up-regulation
AGC_Akt_AKT1_ST	P54253	ATXN1	P31749	AKT1	S406	H402Y	402	Missense	distal	-4	no	12.949	13.063	EPSD	ICGC;COSMIC;GDSC;CCLE	7.780	Up-regulation
AGC_Akt_AKT1_ST	P54253	ATXN1	P31749	AKT1	S408	T409N	409	Missense	proximal	1	no	8.502	8.221	EPSD	ICGC;COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	P54253	ATXN1	P31749	AKT1	S408	R403C	403	Missense	distal	-5	no	8.502	4.426	EPSD	ICGC;COSMIC	7.780	Loss
AGC_Akt_AKT1_ST	P54253	ATXN1	P31749	AKT1	S408	P407S	407	Missense	proximal	-1	no	8.502	8.531	EPSD	ICGC	7.780	Up-regulation
AGC_Akt_AKT1_ST	P54253	ATXN1	P31749	AKT1	S408	H402Y	402	Missense	distal	-6	no	8.502	8.528	EPSD	ICGC;COSMIC;GDSC;CCLE	7.780	Up-regulation
AGC_Akt_AKT1_ST	P54253	ATXN1	P31749	AKT1	S775	T769K	769	Missense	distal	-6	no	17.674	17.663	PhosphoSitePlus	ICGC	7.780	Down-regulation
AGC_Akt_AKT1_ST	P54253	ATXN1	P31749	AKT1	S775	R770K	770	Missense	distal	-5	no	17.674	15.276	PhosphoSitePlus	ICGC	7.780	Down-regulation
AGC_Akt_AKT1_ST	P54253	ATXN1	P31749	AKT1	S775	A776E	776	Missense	proximal	1	no	17.674	17.651	PhosphoSitePlus	ICGC	7.780	Down-regulation
AGC_Akt_AKT1_ST	Q9BRS8	LARP6	P31749	AKT1	S51	D45E	45	Missense	distal	-6	no	10.446	10.518	EPSD	ICGC;COSMIC	7.780	Up-regulation
AGC_Akt_AKT1_ST	Q9BRS8	LARP6	P31749	AKT1	S67	E61V	61	Missense	distal	-6	no	12.326	12.297	EPSD	ICGC;COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	Q9BRS8	LARP6	P31749	AKT1	S247	P241T	241	Missense	distal	-6	no	11.465	11.560	EPSD	ICGC;COSMIC	7.780	Up-regulation
AGC_Akt_AKT1_ST	Q9BRS8	LARP6	P31749	AKT1	S247	S251C	251	Missense	distal	4	no	11.465	11.810	EPSD	ICGC;COSMIC	7.780	Up-regulation
AGC_Akt_AKT1_ST	Q9BRS8	LARP6	P31749	AKT1	S447	G442R	442	Missense	distal	-5	no	5.562	9.626	EPSD	ICGC;COSMIC	7.780	Gain
AGC_Akt_AKT1_ST	Q9BRS8	LARP6	P31749	AKT1	S451	P452S	452	Missense	proximal	1	no	7.702	7.857	PhosphoSitePlus	ICGC	7.780	Gain
AGC_Akt_AKT1_ST	P07550	ADRB2	P31749	AKT1	T68	R63L	63	Missense	distal	-5	no	8.233	4.107	EPSD	ICGC	7.780	Loss
AGC_Akt_AKT1_ST	P07550	ADRB2	P31749	AKT1	S262	R259H	259	Missense	distal	-3	no	12.766	8.068	EPSD	ICGC;COSMIC;GDSC;CCLE	7.780	Down-regulation
AGC_Akt_AKT1_ST	P07550	ADRB2	P31749	AKT1	S262	K267N	267	Missense	distal	5	no	12.766	12.731	EPSD	ICGC;COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	P07550	ADRB2	P31749	AKT1	S346	N352H	352	Missense	distal	6	no	13.056	13.003	PhosphoSitePlus	ICGC	7.780	Down-regulation
AGC_Akt_AKT1_ST	P07550	ADRB2	P31749	AKT1	S346	L340M	340	Missense	distal	-6	no	13.056	13.045	PhosphoSitePlus	ICGC	7.780	Down-regulation
AGC_Akt_AKT1_ST	P07550	ADRB2	P31749	AKT1	S407	N405I	405	Missense	proximal	-2	no	13.355	12.799	EPSD	ICGC	7.780	Down-regulation
AGC_Akt_AKT1_ST	P07550	ADRB2	P31749	AKT1	S407	D400Y	400	Missense	distal	-7	no	13.355	13.520	EPSD	ICGC	7.780	Up-regulation
AGC_Akt_AKT1_ST	P04150	NR3C1	P31749	AKT1	S6	S3F	3	Missense	distal	-3	no	5.649	7.831	EPSD	ICGC	7.780	Gain
AGC_Akt_AKT1_ST	P04150	NR3C1	P31749	AKT1	T8	S3F	3	Missense	distal	-5	no	6.852	7.800	EPSD	ICGC	7.780	Gain
AGC_Akt_AKT1_ST	P04150	NR3C1	P31749	AKT1	S16	E13Q	13	Missense	distal	-3	no	8.249	7.609	EPSD	ICGC;COSMIC	7.780	Loss
AGC_Akt_AKT1_ST	P04150	NR3C1	P31749	AKT1	S16	R23S	23	Missense	distal	7	no	8.249	8.242	EPSD	ICGC;COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	P04150	NR3C1	P31749	AKT1	S134	N138K	138	Missense	distal	4	no	12.534	12.402	PhosphoSitePlus	ICGC	7.780	Down-regulation
AGC_Akt_AKT1_ST	P04150	NR3C1	P31749	AKT1	S134	R131M	131	Missense	distal	-3	no	12.534	5.028	PhosphoSitePlus	ICGC;COSMIC	7.780	Loss
AGC_Akt_AKT1_ST	P04150	NR3C1	P31749	AKT1	S404	T411S	411	Missense	distal	7	no	10.029	10.018	EPSD	ICGC;COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	Q9H4A3	WNK1	P31749	AKT1	S10	T12A	12	Missense	proximal	2	no	8.025	7.724	EPSD	ICGC;COSMIC	7.780	Loss
AGC_Akt_AKT1_ST	Q9H4A3	WNK1	P31749	AKT1	S10	G3C	3	Missense	distal	-7	no	8.025	7.788	EPSD	ICGC;COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	Q9H4A3	WNK1	P31749	AKT1	S11	T12A	12	Missense	proximal	1	no	8.753	8.487	EPSD	ICGC;COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	Q9H4A3	WNK1	P31749	AKT1	T60	R57H	57	Missense	distal	-3	no	14.328	9.629	PhosphoSitePlus	ICGC;COSMIC;GDSC;CCLE	7.780	Down-regulation
AGC_Akt_AKT1_ST	Q9H4A3	WNK1	P31749	AKT1	T60	G67E	67	Missense	distal	7	no	14.328	14.367	PhosphoSitePlus	ICGC	7.780	Up-regulation
AGC_Akt_AKT1_ST	Q9H4A3	WNK1	P31749	AKT1	T60	E53D	53	Missense	distal	-7	no	14.328	14.106	PhosphoSitePlus	ICGC	7.780	Down-regulation
AGC_Akt_AKT1_ST	Q9H4A3	WNK1	P31749	AKT1	T60	R66S	66	Missense	distal	6	no	14.328	14.329	PhosphoSitePlus	ICGC;GDSC;CCLE	7.780	Up-regulation
AGC_Akt_AKT1_ST	Q9H4A3	WNK1	P31749	AKT1	T60	H59N	59	Missense	proximal	-1	no	14.328	14.344	PhosphoSitePlus	ICGC;COSMIC	7.780	Up-regulation
AGC_Akt_AKT1_ST	Q9H4A3	WNK1	P31749	AKT1	T60	R56C	56	Missense	distal	-4	no	14.328	12.649	PhosphoSitePlus	ICGC;COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	Q9H4A3	WNK1	P31749	AKT1	T60	R55G	55	Missense	distal	-5	no	14.328	10.263	PhosphoSitePlus	ICGC;COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	Q9H4A3	WNK1	P31749	AKT1	T60	T60I	60	Missense	central	0	yes	14.328	0.000	PhosphoSitePlus	ICGC;COSMIC	7.780	Loss
AGC_Akt_AKT1_ST	Q9H4A3	WNK1	P31749	AKT1	T71	A70V	70	Missense	proximal	-1	no	9.211	9.197	EPSD	ICGC;COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	Q9H4A3	WNK1	P31749	AKT1	T71	G67E	67	Missense	distal	-4	no	9.211	9.429	EPSD	ICGC	7.780	Up-regulation
AGC_Akt_AKT1_ST	Q9H4A3	WNK1	P31749	AKT1	T71	R66S	66	Missense	distal	-5	no	9.211	4.741	EPSD	ICGC;GDSC;CCLE	7.780	Loss
AGC_Akt_AKT1_ST	Q9H4A3	WNK1	P31749	AKT1	S185	P178L	178	Missense	distal	-7	no	11.024	10.985	EPSD	ICGC	7.780	Down-regulation
AGC_Akt_AKT1_ST	Q9H4A3	WNK1	P31749	AKT1	S185	P179S	179	Missense	distal	-6	no	11.024	11.088	EPSD	ICGC;COSMIC	7.780	Up-regulation
AGC_Akt_AKT1_ST	Q9H4A3	WNK1	P31749	AKT1	S1105	S1105R	1105	Missense	central	0	yes	9.494	0.000	EPSD	ICGC	7.780	Loss
AGC_Akt_AKT1_ST	Q9H4A3	WNK1	P31749	AKT1	S1108	S1105R	1105	Missense	distal	-3	no	9.070	16.846	EPSD	ICGC	7.780	Up-regulation
AGC_Akt_AKT1_ST	Q9H4A3	WNK1	P31749	AKT1	S1110	S1105R	1105	Missense	distal	-5	no	10.716	15.186	EPSD	ICGC	7.780	Up-regulation
AGC_Akt_AKT1_ST	Q9NPC1	LTB4R2	P31749	AKT1	S246	V253L	253	Missense	distal	7	no	11.137	11.126	EPSD	ICGC;COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	Q9NPC1	LTB4R2	P31749	AKT1	T336	G343R	343	Missense	distal	7	no	10.072	10.153	EPSD	ICGC;COSMIC	7.780	Up-regulation
AGC_Akt_AKT1_ST	Q9NPC1	LTB4R2	P31749	AKT1	T336	R329Q	329	Missense	distal	-7	no	10.072	9.878	EPSD	ICGC	7.780	Down-regulation
AGC_Akt_AKT1_ST	Q9NPC1	LTB4R2	P31749	AKT1	S342	R346Q	346	Missense	distal	4	no	10.051	10.174	EPSD	ICGC;COSMIC	7.780	Up-regulation
AGC_Akt_AKT1_ST	Q9NPC1	LTB4R2	P31749	AKT1	S342	G343R	343	Missense	proximal	1	no	10.051	10.501	EPSD	ICGC;COSMIC	7.780	Up-regulation
AGC_Akt_AKT1_ST	Q9NPC1	LTB4R2	P31749	AKT1	T355	E357Q	357	Missense	proximal	2	no	15.917	15.816	EPSD	ICGC;COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	Q9NPC1	LTB4R2	P31749	AKT1	T355	R359Q	359	Missense	distal	4	no	15.917	16.040	EPSD	ICGC	7.780	Up-regulation
AGC_Akt_AKT1_ST	Q9NPC1	LTB4R2	P31749	AKT1	T355	E357D	357	Missense	proximal	2	no	15.917	15.507	EPSD	ICGC	7.780	Down-regulation
AGC_Akt_AKT1_ST	Q9NPC1	LTB4R2	P31749	AKT1	T355	R350H	350	Missense	distal	-5	no	15.917	12.822	EPSD	ICGC	7.780	Down-regulation
AGC_Akt_AKT1_ST	Q9NPC1	LTB4R2	P31749	AKT1	T355	S351C	351	Missense	distal	-4	no	15.917	14.324	EPSD	ICGC;COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	Q9NPC1	LTB4R2	P31749	AKT1	T355	R352G	352	Missense	distal	-3	no	15.917	9.161	EPSD	ICGC;COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	Q9NPC1	LTB4R2	P31749	AKT1	T355	G354R	354	Missense	proximal	-1	no	15.917	15.957	EPSD	ICGC;COSMIC	7.780	Up-regulation
AGC_Akt_AKT1_ST	P21333	FLNA	P31749	AKT1	S343	Y346H	346	Missense	distal	3	no	14.230	14.198	EPSD	ICGC;COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	P21333	FLNA	P31749	AKT1	S343	R340C	340	Missense	distal	-3	no	14.230	8.056	EPSD	ICGC;COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	P21333	FLNA	P31749	AKT1	S343	F342L	342	Missense	proximal	-1	no	14.230	14.236	EPSD	ICGC;COSMIC	7.780	Up-regulation
AGC_Akt_AKT1_ST	P21333	FLNA	P31749	AKT1	S343	V347I	347	Missense	distal	4	no	14.230	14.311	EPSD	ICGC;COSMIC	7.780	Up-regulation
AGC_Akt_AKT1_ST	P21333	FLNA	P31749	AKT1	S440	D439N	439	Missense	proximal	-1	no	11.952	11.982	EPSD	ICGC	7.780	Up-regulation
AGC_Akt_AKT1_ST	P21333	FLNA	P31749	AKT1	S440	Q447K	447	Missense	distal	7	no	11.952	12.000	EPSD	ICGC;COSMIC	7.780	Up-regulation
AGC_Akt_AKT1_ST	P21333	FLNA	P31749	AKT1	S734	Y731H	731	Missense	distal	-3	no	6.390	9.280	EPSD	ICGC;COSMIC	7.780	Gain
AGC_Akt_AKT1_ST	P21333	FLNA	P31749	AKT1	T790	T793I	793	Missense	distal	3	no	8.600	8.470	EPSD	ICGC	7.780	Down-regulation
AGC_Akt_AKT1_ST	P21333	FLNA	P31749	AKT1	T833	N831S	831	Missense	proximal	-2	no	9.292	9.978	EPSD	ICGC;COSMIC	7.780	Up-regulation
AGC_Akt_AKT1_ST	P21333	FLNA	P31749	AKT1	T833	N831K	831	Missense	proximal	-2	no	9.292	10.228	EPSD	ICGC;COSMIC	7.780	Up-regulation
AGC_Akt_AKT1_ST	P21333	FLNA	P31749	AKT1	T1286	H1292R	1292	Missense	distal	6	no	12.037	12.157	EPSD	ICGC;COSMIC	7.780	Up-regulation
AGC_Akt_AKT1_ST	P21333	FLNA	P31749	AKT1	T1286	V1293I	1293	Missense	distal	7	no	12.037	11.995	EPSD	ICGC;COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	P21333	FLNA	P31749	AKT1	T1288	H1292R	1292	Missense	distal	4	no	8.034	7.849	EPSD	ICGC;COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	P21333	FLNA	P31749	AKT1	T1288	V1293I	1293	Missense	distal	5	no	8.034	7.997	EPSD	ICGC;COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	P21333	FLNA	P31749	AKT1	S1301	N1299K	1299	Missense	proximal	-2	no	7.248	8.185	EPSD	ICGC	7.780	Gain
AGC_Akt_AKT1_ST	P21333	FLNA	P31749	AKT1	S1367	G1362R	1362	Missense	distal	-5	no	4.606	8.670	EPSD	ICGC;COSMIC	7.780	Gain
AGC_Akt_AKT1_ST	P21333	FLNA	P31749	AKT1	S1520	P1518T	1518	Missense	proximal	-2	no	7.055	7.813	EPSD	ICGC	7.780	Gain
AGC_Akt_AKT1_ST	P21333	FLNA	P31749	AKT1	S1522	Y1519H	1519	Missense	distal	-3	no	4.953	7.843	EPSD	ICGC;CCLE	7.780	Gain
AGC_Akt_AKT1_ST	P21333	FLNA	P31749	AKT1	S2372	A2366S	2366	Missense	distal	-6	no	8.250	8.305	EPSD	ICGC;COSMIC	7.780	Up-regulation
AGC_Akt_AKT1_ST	P30291	WEE1	P31749	AKT1	S204	D202Y	202	Missense	proximal	-2	no	7.503	7.975	EPSD	ICGC;COSMIC	7.780	Gain
AGC_Akt_AKT1_ST	P30291	WEE1	P31749	AKT1	S212	M215I	215	Missense	distal	3	no	13.593	13.547	EPSD	ICGC;COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	P30291	WEE1	P31749	AKT1	S212	G210C	210	Missense	proximal	-2	no	13.593	12.635	EPSD	ICGC;COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	P30291	WEE1	P31749	AKT1	T257	W259R	259	Missense	proximal	2	no	14.609	15.064	EPSD	ICGC;COSMIC	7.780	Up-regulation
AGC_Akt_AKT1_ST	P30291	WEE1	P31749	AKT1	S262	W259R	259	Missense	distal	-3	no	2.251	11.192	EPSD	ICGC;COSMIC	7.780	Gain
AGC_Akt_AKT1_ST	P30291	WEE1	P31749	AKT1	S472	H466Y	466	Missense	distal	-6	no	10.961	10.986	EPSD	ICGC	7.780	Up-regulation
AGC_Akt_AKT1_ST	P30291	WEE1	P31749	AKT1	S559	A560S	560	Missense	proximal	1	no	10.760	10.833	EPSD	ICGC;COSMIC	7.780	Up-regulation
AGC_Akt_AKT1_ST	P30291	WEE1	P31749	AKT1	S592	E587K	587	Missense	distal	-5	no	6.995	8.693	EPSD	ICGC;COSMIC	7.780	Gain
AGC_Akt_AKT1_ST	P30291	WEE1	P31749	AKT1	S642	R639C	639	Missense	distal	-3	no	13.451	7.278	PhosphoSitePlus	ICGC;COSMIC	7.780	Loss
AGC_Akt_AKT1_ST	P30291	WEE1	P31749	AKT1	S642	S642I	642	Missense	central	0	yes	13.451	0.000	PhosphoSitePlus	ICGC;COSMIC	7.780	Loss
AGC_Akt_AKT1_ST	P30291	WEE1	P31749	AKT1	T644	R639C	639	Missense	distal	-5	no	10.057	5.980	EPSD	ICGC;COSMIC	7.780	Loss
AGC_Akt_AKT1_ST	P30291	WEE1	P31749	AKT1	T644	S642I	642	Missense	proximal	-2	no	10.057	8.816	EPSD	ICGC;COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	P78371	CCT2	P31749	AKT1	T23	A24S	24	Missense	proximal	1	no	11.010	11.084	EPSD	ICGC;COSMIC	7.780	Up-regulation
AGC_Akt_AKT1_ST	P78371	CCT2	P31749	AKT1	T23	A24D	24	Missense	proximal	1	no	11.010	10.871	EPSD	ICGC;COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	P78371	CCT2	P31749	AKT1	S28	A32S	32	Missense	distal	4	no	10.688	10.564	EPSD	ICGC	7.780	Down-regulation
AGC_Akt_AKT1_ST	P78371	CCT2	P31749	AKT1	S28	A24S	24	Missense	distal	-4	no	10.688	11.410	EPSD	ICGC;COSMIC	7.780	Up-regulation
AGC_Akt_AKT1_ST	P78371	CCT2	P31749	AKT1	S28	A24D	24	Missense	distal	-4	no	10.688	10.122	EPSD	ICGC;COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	P78371	CCT2	P31749	AKT1	S60	D66H	66	Missense	distal	6	no	9.293	9.322	EPSD	ICGC;COSMIC	7.780	Up-regulation
AGC_Akt_AKT1_ST	P78371	CCT2	P31749	AKT1	S60	R57L	57	Missense	distal	-3	no	9.293	2.299	EPSD	ICGC	7.780	Loss
AGC_Akt_AKT1_ST	P78371	CCT2	P31749	AKT1	S60	D58Y	58	Missense	proximal	-2	no	9.293	9.765	EPSD	ICGC;COSMIC	7.780	Up-regulation
AGC_Akt_AKT1_ST	P78371	CCT2	P31749	AKT1	S60	V63I	63	Missense	distal	3	no	9.293	9.252	EPSD	ICGC;COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	P78371	CCT2	P31749	AKT1	T134	A137V	137	Missense	distal	3	no	10.179	10.147	EPSD	ICGC	7.780	Down-regulation
AGC_Akt_AKT1_ST	P78371	CCT2	P31749	AKT1	S143	A137V	137	Missense	distal	-6	no	8.120	8.099	EPSD	ICGC	7.780	Down-regulation
AGC_Akt_AKT1_ST	P78371	CCT2	P31749	AKT1	S260	E266A	266	Missense	distal	6	no	13.404	13.381	PhosphoSitePlus	ICGC;COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	P78371	CCT2	P31749	AKT1	S260	G253C	253	Missense	distal	-7	no	13.404	13.168	PhosphoSitePlus	ICGC	7.780	Down-regulation
AGC_Akt_AKT1_ST	P78371	CCT2	P31749	AKT1	S260	V264F	264	Missense	distal	4	no	13.404	13.421	PhosphoSitePlus	ICGC	7.780	Up-regulation
AGC_Akt_AKT1_ST	P78371	CCT2	P31749	AKT1	S260	E266G	266	Missense	distal	6	no	13.404	13.358	PhosphoSitePlus	ICGC	7.780	Down-regulation
AGC_Akt_AKT1_ST	P78371	CCT2	P31749	AKT1	S260	T261I	261	Missense	proximal	1	no	13.404	12.963	PhosphoSitePlus	ICGC	7.780	Down-regulation
AGC_Akt_AKT1_ST	P78371	CCT2	P31749	AKT1	T379	R376C	376	Missense	distal	-3	no	10.191	4.017	EPSD	ICGC;COSMIC	7.780	Loss
AGC_Akt_AKT1_ST	P41279	MAP3K8	P31749	AKT1	S62	K61E	61	Missense	proximal	-1	no	12.056	12.035	EPSD	ICGC	7.780	Down-regulation
AGC_Akt_AKT1_ST	P41279	MAP3K8	P31749	AKT1	S62	G67C	67	Missense	distal	5	no	12.056	12.000	EPSD	ICGC;COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	P41279	MAP3K8	P31749	AKT1	S62	R59H	59	Missense	distal	-3	no	12.056	7.357	EPSD	ICGC	7.780	Loss
AGC_Akt_AKT1_ST	P41279	MAP3K8	P31749	AKT1	T80	L73F	73	Missense	distal	-7	no	8.593	8.549	EPSD	ICGC;COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	P41279	MAP3K8	P31749	AKT1	S400	C398Y	398	Missense	proximal	-2	no	11.067	11.798	PhosphoSitePlus	ICGC;COSMIC	7.780	Up-regulation
AGC_Akt_AKT1_ST	P41279	MAP3K8	P31749	AKT1	S400	L405I	405	Missense	distal	5	no	11.067	11.037	PhosphoSitePlus	ICGC;COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	P41279	MAP3K8	P31749	AKT1	S413	E416D	416	Missense	distal	3	no	15.465	15.394	EPSD	ICGC	7.780	Down-regulation
AGC_Akt_AKT1_ST	P41279	MAP3K8	P31749	AKT1	S443	I446M	446	Missense	distal	3	no	12.799	12.845	EPSD	ICGC;COSMIC	7.780	Up-regulation
AGC_Akt_AKT1_ST	P41279	MAP3K8	P31749	AKT1	S443	G449A	449	Missense	distal	6	no	12.799	12.822	EPSD	ICGC;COSMIC	7.780	Up-regulation
AGC_Akt_AKT1_ST	P41279	MAP3K8	P31749	AKT1	S443	A450T	450	Missense	distal	7	no	12.799	12.860	EPSD	ICGC;COSMIC	7.780	Up-regulation
AGC_Akt_AKT1_ST	Q96QB1	DLC1	P31749	AKT1	S354	A350V	350	Missense	distal	-4	no	14.062	13.690	EPSD	ICGC;COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	Q96QB1	DLC1	P31749	AKT1	S354	L352M	352	Missense	proximal	-2	no	14.062	14.079	EPSD	ICGC;COSMIC	7.780	Up-regulation
AGC_Akt_AKT1_ST	Q96QB1	DLC1	P31749	AKT1	S354	S354Y	354	Missense	central	0	yes	14.062	0.000	EPSD	ICGC	7.780	Loss
AGC_Akt_AKT1_ST	Q96QB1	DLC1	P31749	AKT1	S377	S374R	374	Missense	distal	-3	no	4.768	12.544	EPSD	ICGC	7.780	Gain
AGC_Akt_AKT1_ST	Q96QB1	DLC1	P31749	AKT1	S548	R542S	542	Missense	distal	-6	no	8.566	8.531	EPSD	ICGC;COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	Q96QB1	DLC1	P31749	AKT1	S548	R546T	546	Missense	proximal	-2	no	8.566	8.688	EPSD	ICGC	7.780	Up-regulation
AGC_Akt_AKT1_ST	Q96QB1	DLC1	P31749	AKT1	S548	R542W	542	Missense	distal	-6	no	8.566	8.418	EPSD	ICGC;COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	Q96QB1	DLC1	P31749	AKT1	S598	S596R	596	Missense	proximal	-2	no	10.137	9.949	EPSD	ICGC	7.780	Down-regulation
AGC_Akt_AKT1_ST	Q96QB1	DLC1	P31749	AKT1	S599	S596R	596	Missense	distal	-3	no	3.065	10.841	EPSD	ICGC	7.780	Gain
AGC_Akt_AKT1_ST	Q96QB1	DLC1	P31749	AKT1	T600	S596R	596	Missense	distal	-4	no	8.833	8.918	EPSD	ICGC	7.780	Up-regulation
AGC_Akt_AKT1_ST	Q96QB1	DLC1	P31749	AKT1	S673	S678N	678	Missense	distal	5	no	11.401	11.366	EPSD	ICGC;COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	Q96QB1	DLC1	P31749	AKT1	S673	S679L	679	Missense	distal	6	no	11.401	11.297	EPSD	ICGC;COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	Q96QB1	DLC1	P31749	AKT1	S764	S766N	766	Missense	proximal	2	no	12.778	12.509	EPSD	ICGC;COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	Q96QB1	DLC1	P31749	AKT1	S766	S766N	766	Missense	central	0	yes	15.353	0.000	EPSD;PhosphoSitePlus	ICGC;COSMIC	7.780	Loss
AGC_Akt_AKT1_ST	Q96QB1	DLC1	P31749	AKT1	S856	S859Y	859	Missense	distal	3	no	11.907	11.839	EPSD	ICGC;COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	Q96QB1	DLC1	P31749	AKT1	S857	S859Y	859	Missense	proximal	2	no	9.035	8.663	EPSD	ICGC;COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	Q96QB1	DLC1	P31749	AKT1	S869	L876M	876	Missense	distal	7	no	13.477	13.485	EPSD	ICGC;COSMIC	7.780	Up-regulation
AGC_Akt_AKT1_ST	Q96QB1	DLC1	P31749	AKT1	S870	L876M	876	Missense	distal	6	no	10.064	10.069	EPSD	ICGC;COSMIC	7.780	Up-regulation
AGC_Akt_AKT1_ST	Q96QB1	DLC1	P31749	AKT1	S1516	R1512Q	1512	Missense	distal	-4	no	9.256	8.635	EPSD	ICGC;COSMIC;GDSC;CCLE	7.780	Down-regulation
AGC_Akt_AKT1_ST	P26373	RPL13	P31749	AKT1	S52	R45H	45	Missense	distal	-7	no	10.337	10.036	EPSD	ICGC;COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	P26373	RPL13	P31749	AKT1	S52	R56W	56	Missense	distal	4	no	10.337	10.584	EPSD	ICGC;COSMIC	7.780	Up-regulation
AGC_Akt_AKT1_ST	P26373	RPL13	P31749	AKT1	S77	L81F	81	Missense	distal	4	no	10.529	10.536	EPSD	ICGC;COSMIC	7.780	Up-regulation
AGC_Akt_AKT1_ST	P26373	RPL13	P31749	AKT1	S77	A72T	72	Missense	distal	-5	no	10.529	10.653	EPSD	ICGC;COSMIC	7.780	Up-regulation
AGC_Akt_AKT1_ST	P26373	RPL13	P31749	AKT1	T170	R167G	167	Missense	distal	-3	no	11.384	4.628	EPSD	ICGC	7.780	Loss
AGC_Akt_AKT1_ST	P55072	VCP	P31749	AKT1	T56	T56I	56	Missense	central	0	yes	10.933	0.000	EPSD	ICGC	7.780	Loss
AGC_Akt_AKT1_ST	P55072	VCP	P31749	AKT1	T316	R322W	322	Missense	distal	6	no	12.127	11.968	EPSD	ICGC;COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	P55072	VCP	P31749	AKT1	S326	R322W	322	Missense	distal	-4	no	11.518	9.969	EPSD	ICGC;COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	P55072	VCP	P31749	AKT1	S705	S702Y	702	Missense	distal	-3	no	8.293	8.480	EPSD	ICGC;COSMIC	7.780	Up-regulation
AGC_Akt_AKT1_ST	P55072	VCP	P31749	AKT1	S718	N716S	716	Missense	proximal	-2	no	8.543	9.229	EPSD	ICGC;COSMIC	7.780	Up-regulation
AGC_Akt_AKT1_ST	P55072	VCP	P31749	AKT1	S746	R745C	745	Missense	proximal	-1	no	11.046	10.975	EPSD;PhosphoSitePlus	ICGC	7.780	Down-regulation
AGC_Akt_AKT1_ST	P55072	VCP	P31749	AKT1	S746	R744H	744	Missense	proximal	-2	no	11.046	10.185	EPSD;PhosphoSitePlus	ICGC;COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	P55072	VCP	P31749	AKT1	S746	D751E	751	Missense	distal	5	no	11.046	11.088	EPSD;PhosphoSitePlus	ICGC	7.780	Up-regulation
AGC_Akt_AKT1_ST	P55072	VCP	P31749	AKT1	S746	R741H	741	Missense	distal	-5	no	11.046	7.951	EPSD;PhosphoSitePlus	ICGC;COSMIC;CCLE	7.780	Down-regulation
AGC_Akt_AKT1_ST	P55072	VCP	P31749	AKT1	S746	M740V	740	Missense	distal	-6	no	11.046	11.032	EPSD;PhosphoSitePlus	ICGC;COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	P55072	VCP	P31749	AKT1	S748	R745C	745	Missense	distal	-3	no	12.791	6.618	EPSD;PhosphoSitePlus	ICGC	7.780	Loss
AGC_Akt_AKT1_ST	P55072	VCP	P31749	AKT1	S748	R744H	744	Missense	distal	-4	no	12.791	11.732	EPSD;PhosphoSitePlus	ICGC;COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	P55072	VCP	P31749	AKT1	S748	D751E	751	Missense	distal	3	no	12.791	12.862	EPSD;PhosphoSitePlus	ICGC	7.780	Up-regulation
AGC_Akt_AKT1_ST	P55072	VCP	P31749	AKT1	S748	R741H	741	Missense	distal	-7	no	12.791	12.490	EPSD;PhosphoSitePlus	ICGC;COSMIC;CCLE	7.780	Down-regulation
AGC_Akt_AKT1_ST	Q92793	CREBBP	P31749	AKT1	S381	N374K	374	Missense	distal	-7	no	11.446	11.603	EPSD	ICGC	7.780	Up-regulation
AGC_Akt_AKT1_ST	Q92793	CREBBP	P31749	AKT1	S745	Q752K	752	Missense	distal	7	no	12.849	12.897	EPSD	ICGC;COSMIC	7.780	Up-regulation
AGC_Akt_AKT1_ST	Q92793	CREBBP	P31749	AKT1	S1108	D1105H	1105	Missense	distal	-3	no	9.863	11.115	EPSD	ICGC;COSMIC	7.780	Up-regulation
AGC_Akt_AKT1_ST	Q92793	CREBBP	P31749	AKT1	T1931	R1926C	1926	Missense	distal	-5	no	8.972	4.895	EPSD	ICGC;COSMIC	7.780	Loss
AGC_Akt_AKT1_ST	Q92793	CREBBP	P31749	AKT1	T1931	R1926H	1926	Missense	distal	-5	no	8.972	5.877	EPSD	ICGC;COSMIC	7.780	Loss
AGC_Akt_AKT1_ST	P08670	VIM	P31749	AKT1	S26	P24L	24	Missense	proximal	-2	no	11.796	11.763	EPSD	ICGC;COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	P08670	VIM	P31749	AKT1	S26	V31A	31	Missense	distal	5	no	11.796	11.804	EPSD	ICGC	7.780	Up-regulation
AGC_Akt_AKT1_ST	P08670	VIM	P31749	AKT1	S39	R45H	45	Missense	distal	6	no	11.642	11.523	PhosphoSitePlus	ICGC	7.780	Down-regulation
AGC_Akt_AKT1_ST	P08670	VIM	P31749	AKT1	S39	R36S	36	Missense	distal	-3	no	11.642	3.866	PhosphoSitePlus	ICGC;COSMIC	7.780	Loss
AGC_Akt_AKT1_ST	P08670	VIM	P31749	AKT1	T48	R45H	45	Missense	distal	-3	no	9.132	4.433	EPSD	ICGC	7.780	Loss
AGC_Akt_AKT1_ST	P08670	VIM	P31749	AKT1	T48	S55L	55	Missense	distal	7	no	9.132	9.065	EPSD	ICGC	7.780	Down-regulation
AGC_Akt_AKT1_ST	P08670	VIM	P31749	AKT1	T48	A54G	54	Missense	distal	6	no	9.132	9.109	EPSD	ICGC	7.780	Down-regulation
AGC_Akt_AKT1_ST	P08670	VIM	P31749	AKT1	S55	S55L	55	Missense	central	0	yes	8.851	0.000	EPSD	ICGC	7.780	Loss
AGC_Akt_AKT1_ST	P08670	VIM	P31749	AKT1	S55	A54G	54	Missense	proximal	-1	no	8.851	8.842	EPSD	ICGC	7.780	Down-regulation
AGC_Akt_AKT1_ST	P08670	VIM	P31749	AKT1	S55	A62V	62	Missense	distal	7	no	8.851	8.847	EPSD	ICGC	7.780	Down-regulation
AGC_Akt_AKT1_ST	P08670	VIM	P31749	AKT1	S278	R273H	273	Missense	distal	-5	no	8.023	4.928	EPSD	ICGC	7.780	Loss
AGC_Akt_AKT1_ST	P08670	VIM	P31749	AKT1	S278	R273G	273	Missense	distal	-5	no	8.023	3.959	EPSD	ICGC	7.780	Loss
AGC_Akt_AKT1_ST	P08670	VIM	P31749	AKT1	S325	S325Y	325	Missense	central	0	yes	7.881	0.000	EPSD	ICGC;COSMIC	7.780	Loss
AGC_Akt_AKT1_ST	P08670	VIM	P31749	AKT1	S325	D331E	331	Missense	distal	6	no	7.881	7.971	EPSD	ICGC;COSMIC	7.780	Up-regulation
AGC_Akt_AKT1_ST	P08670	VIM	P31749	AKT1	S325	V323L	323	Missense	proximal	-2	no	7.881	8.215	EPSD	ICGC;COSMIC	7.780	Up-regulation
AGC_Akt_AKT1_ST	Q7L5N1	COPS6	P31749	AKT1	S60	Q67H	67	Missense	distal	7	no	9.584	9.568	PhosphoSitePlus	ICGC;COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	Q16763	UBE2S	P31749	AKT1	T152	G159S	159	Missense	distal	7	no	13.745	13.818	PhosphoSitePlus	ICGC;COSMIC	7.780	Up-regulation
AGC_Akt_AKT1_ST	Q16763	UBE2S	P31749	AKT1	T152	A148S	148	Missense	distal	-4	no	13.745	14.467	PhosphoSitePlus	ICGC;COSMIC	7.780	Up-regulation
AGC_Akt_AKT1_ST	Q96F86	EDC3	P31749	AKT1	S125	P132Q	132	Missense	distal	7	no	8.609	8.619	EPSD	ICGC	7.780	Up-regulation
AGC_Akt_AKT1_ST	Q96F86	EDC3	P31749	AKT1	S233	S229N	229	Missense	distal	-4	no	11.116	10.549	EPSD	ICGC	7.780	Down-regulation
AGC_Akt_AKT1_ST	Q96F86	EDC3	P31749	AKT1	S233	R232C	232	Missense	proximal	-1	no	11.116	11.045	EPSD	ICGC	7.780	Down-regulation
AGC_Akt_AKT1_ST	Q96F86	EDC3	P31749	AKT1	S233	R232S	232	Missense	proximal	-1	no	11.116	11.106	EPSD	ICGC;COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	Q96F86	EDC3	P31749	AKT1	T300	E295K	295	Missense	distal	-5	no	7.002	8.700	EPSD	ICGC;COSMIC	7.780	Gain
AGC_Akt_AKT1_ST	Q96F86	EDC3	P31749	AKT1	T308	A312D	312	Missense	distal	4	no	8.418	8.519	EPSD	ICGC	7.780	Up-regulation
AGC_Akt_AKT1_ST	P14598	NCF1	P31749	AKT1	T45	E46K	46	Missense	proximal	1	no	11.183	11.346	EPSD	ICGC	7.780	Up-regulation
AGC_Akt_AKT1_ST	P14598	NCF1	P31749	AKT1	T93	R90H	90	Missense	distal	-3	no	12.081	7.383	EPSD	ICGC;COSMIC	7.780	Loss
AGC_Akt_AKT1_ST	P14598	NCF1	P31749	AKT1	T93	G99S	99	Missense	distal	6	no	12.081	12.187	EPSD	ICGC	7.780	Up-regulation
AGC_Akt_AKT1_ST	P14598	NCF1	P31749	AKT1	T95	R90H	90	Missense	distal	-5	no	9.024	5.929	EPSD	ICGC;COSMIC	7.780	Loss
AGC_Akt_AKT1_ST	P14598	NCF1	P31749	AKT1	T95	G99S	99	Missense	distal	4	no	9.024	8.850	EPSD	ICGC	7.780	Down-regulation
AGC_Akt_AKT1_ST	P05455	SSB	P31749	AKT1	S94	P93S	93	Missense	proximal	-1	no	12.297	12.326	EPSD	ICGC;COSMIC	7.780	Up-regulation
AGC_Akt_AKT1_ST	P05455	SSB	P31749	AKT1	S94	P96S	96	Missense	proximal	2	no	12.297	12.633	EPSD	ICGC;COSMIC	7.780	Up-regulation
AGC_Akt_AKT1_ST	P05455	SSB	P31749	AKT1	S94	P93T	93	Missense	proximal	-1	no	12.297	12.332	EPSD	ICGC;COSMIC	7.780	Up-regulation
AGC_Akt_AKT1_ST	P05455	SSB	P31749	AKT1	T302	E309K	309	Missense	distal	7	no	10.727	10.761	EPSD	ICGC;COSMIC	7.780	Up-regulation
AGC_Akt_AKT1_ST	P05455	SSB	P31749	AKT1	T302	K299R	299	Missense	distal	-3	no	10.727	15.247	EPSD	ICGC;COSMIC	7.780	Up-regulation
AGC_Akt_AKT1_ST	P05455	SSB	P31749	AKT1	S366	D368Y	368	Missense	proximal	2	no	8.048	8.275	EPSD	ICGC	7.780	Up-regulation
AGC_Akt_AKT1_ST	P20749	BCL3	P31749	AKT1	S41	A46S	46	Missense	distal	5	no	13.310	13.361	PhosphoSitePlus	ICGC	7.780	Up-regulation
AGC_Akt_AKT1_ST	P20749	BCL3	P31749	AKT1	S367	D372G	372	Missense	distal	5	no	12.624	12.636	EPSD	ICGC;COSMIC	7.780	Up-regulation
AGC_Akt_AKT1_ST	P20749	BCL3	P31749	AKT1	S367	R364Q	364	Missense	distal	-3	no	12.624	5.413	EPSD	ICGC;COSMIC	7.780	Loss
AGC_Akt_AKT1_ST	P20749	BCL3	P31749	AKT1	S367	P371S	371	Missense	distal	4	no	12.624	12.468	EPSD	ICGC	7.780	Down-regulation
AGC_Akt_AKT1_ST	P20749	BCL3	P31749	AKT1	S369	D372G	372	Missense	distal	3	no	9.057	9.077	EPSD	ICGC;COSMIC	7.780	Up-regulation
AGC_Akt_AKT1_ST	P20749	BCL3	P31749	AKT1	S369	R364Q	364	Missense	distal	-5	no	9.057	4.829	EPSD	ICGC;COSMIC	7.780	Loss
AGC_Akt_AKT1_ST	P20749	BCL3	P31749	AKT1	S369	P371S	371	Missense	proximal	2	no	9.057	9.393	EPSD	ICGC	7.780	Up-regulation
AGC_Akt_AKT1_ST	P20749	BCL3	P31749	AKT1	S382	A379T	379	Missense	distal	-3	no	9.514	8.795	EPSD	ICGC	7.780	Down-regulation
AGC_Akt_AKT1_ST	P20749	BCL3	P31749	AKT1	S382	P383R	383	Missense	proximal	1	no	9.514	9.814	EPSD	ICGC	7.780	Up-regulation
AGC_Akt_AKT1_ST	P20749	BCL3	P31749	AKT1	S382	L389H	389	Missense	distal	7	no	9.514	9.516	EPSD	ICGC	7.780	Up-regulation
AGC_Akt_AKT1_ST	P20749	BCL3	P31749	AKT1	S386	P383R	383	Missense	distal	-3	no	6.172	12.812	EPSD	ICGC	7.780	Gain
AGC_Akt_AKT1_ST	P20749	BCL3	P31749	AKT1	S448	V445L	445	Missense	distal	-3	no	9.964	9.836	EPSD	ICGC	7.780	Down-regulation
AGC_Akt_AKT1_ST	Q5UE93	PIK3R6	P31749	AKT1	S22	L21H	21	Missense	proximal	-1	no	11.258	11.252	EPSD	ICGC	7.780	Down-regulation
AGC_Akt_AKT1_ST	Q5UE93	PIK3R6	P31749	AKT1	S22	Q15K	15	Missense	distal	-7	no	11.258	11.439	EPSD	ICGC	7.780	Up-regulation
AGC_Akt_AKT1_ST	Q5UE93	PIK3R6	P31749	AKT1	T125	A120T	120	Missense	distal	-5	no	9.315	9.440	EPSD	ICGC;COSMIC	7.780	Up-regulation
AGC_Akt_AKT1_ST	Q5UE93	PIK3R6	P31749	AKT1	S217	T221S	221	Missense	distal	4	no	9.559	9.564	EPSD	ICGC	7.780	Up-regulation
AGC_Akt_AKT1_ST	Q5UE93	PIK3R6	P31749	AKT1	S217	T221N	221	Missense	distal	4	no	9.559	9.673	EPSD	ICGC;COSMIC	7.780	Up-regulation
AGC_Akt_AKT1_ST	Q5UE93	PIK3R6	P31749	AKT1	S308	R305S	305	Missense	distal	-3	no	10.929	3.153	EPSD	ICGC;COSMIC	7.780	Loss
AGC_Akt_AKT1_ST	Q5UE93	PIK3R6	P31749	AKT1	S308	R311H	311	Missense	distal	3	no	10.929	10.846	EPSD	ICGC	7.780	Down-regulation
AGC_Akt_AKT1_ST	Q5UE93	PIK3R6	P31749	AKT1	S401	G402W	402	Missense	proximal	1	no	9.797	9.954	EPSD	ICGC;COSMIC	7.780	Up-regulation
AGC_Akt_AKT1_ST	Q5UE93	PIK3R6	P31749	AKT1	T442	Q443R	443	Missense	proximal	1	no	8.819	9.114	EPSD	ICGC;COSMIC	7.780	Up-regulation
AGC_Akt_AKT1_ST	Q5UE93	PIK3R6	P31749	AKT1	T448	Q443R	443	Missense	distal	-5	no	3.556	7.784	EPSD	ICGC;COSMIC	7.780	Gain
AGC_Akt_AKT1_ST	Q5UE93	PIK3R6	P31749	AKT1	T607	R602W	602	Missense	distal	-5	no	14.171	8.651	PhosphoSitePlus	ICGC;COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	Q5UE93	PIK3R6	P31749	AKT1	T607	R604Q	604	Missense	distal	-3	no	14.171	6.959	PhosphoSitePlus	ICGC;COSMIC	7.780	Loss
AGC_Akt_AKT1_ST	Q5UE93	PIK3R6	P31749	AKT1	T607	V608I	608	Missense	proximal	1	no	14.171	13.923	PhosphoSitePlus	ICGC;COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	Q5UE93	PIK3R6	P31749	AKT1	T607	S609P	609	Missense	proximal	2	no	14.171	13.835	PhosphoSitePlus	ICGC;COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	Q5UE93	PIK3R6	P31749	AKT1	S609	R602W	602	Missense	distal	-7	no	9.157	8.734	EPSD	ICGC;COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	Q5UE93	PIK3R6	P31749	AKT1	S609	R604Q	604	Missense	distal	-5	no	9.157	4.929	EPSD	ICGC;COSMIC	7.780	Loss
AGC_Akt_AKT1_ST	Q5UE93	PIK3R6	P31749	AKT1	S609	V608I	608	Missense	proximal	-1	no	9.157	9.143	EPSD	ICGC;COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	Q5UE93	PIK3R6	P31749	AKT1	S609	S609P	609	Missense	central	0	yes	9.157	0.000	EPSD	ICGC;COSMIC	7.780	Loss
AGC_Akt_AKT1_ST	Q5UE93	PIK3R6	P31749	AKT1	T687	D693N	693	Missense	distal	6	no	10.628	10.709	EPSD	ICGC	7.780	Up-regulation
AGC_Akt_AKT1_ST	Q5UE93	PIK3R6	P31749	AKT1	S689	D693N	693	Missense	distal	4	no	8.809	8.694	EPSD	ICGC	7.780	Down-regulation
AGC_Akt_AKT1_ST	Q96J02	ITCH	P31749	AKT1	T214	T218A	218	Missense	distal	4	no	8.773	8.902	EPSD	ICGC;COSMIC	7.780	Up-regulation
AGC_Akt_AKT1_ST	Q96J02	ITCH	P31749	AKT1	T214	S221L	221	Missense	distal	7	no	8.773	8.706	EPSD	ICGC;COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	Q96J02	ITCH	P31749	AKT1	T214	S208F	208	Missense	distal	-6	no	8.773	8.698	EPSD	ICGC;COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	Q96J02	ITCH	P31749	AKT1	T214	G207V	207	Missense	distal	-7	no	8.773	8.681	EPSD	ICGC	7.780	Down-regulation
AGC_Akt_AKT1_ST	Q96J02	ITCH	P31749	AKT1	T214	E213D	213	Missense	proximal	-1	no	8.773	8.739	EPSD	ICGC	7.780	Down-regulation
AGC_Akt_AKT1_ST	Q96J02	ITCH	P31749	AKT1	T218	T218A	218	Missense	central	0	yes	10.607	0.000	EPSD	ICGC;COSMIC	7.780	Loss
AGC_Akt_AKT1_ST	Q96J02	ITCH	P31749	AKT1	T218	S221L	221	Missense	distal	3	no	10.607	10.509	EPSD	ICGC;COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	Q96J02	ITCH	P31749	AKT1	T218	E213D	213	Missense	distal	-5	no	10.607	10.656	EPSD	ICGC	7.780	Up-regulation
AGC_Akt_AKT1_ST	Q96J02	ITCH	P31749	AKT1	S257	R255I	255	Missense	proximal	-2	no	8.345	7.293	PhosphoSitePlus	ICGC;COSMIC	7.780	Loss
AGC_Akt_AKT1_ST	Q96J02	ITCH	P31749	AKT1	S257	S251F	251	Missense	distal	-6	no	8.345	8.271	PhosphoSitePlus	ICGC;COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	Q96J02	ITCH	P31749	AKT1	T385	R388S	388	Missense	distal	3	no	11.921	11.937	EPSD	ICGC	7.780	Up-regulation
AGC_Akt_AKT1_ST	Q96J02	ITCH	P31749	AKT1	T385	T385M	385	Missense	central	0	yes	11.921	0.000	EPSD	ICGC;COSMIC	7.780	Loss
AGC_Akt_AKT1_ST	Q96J02	ITCH	P31749	AKT1	T385	E392D	392	Missense	distal	7	no	11.921	11.877	EPSD	ICGC	7.780	Down-regulation
AGC_Akt_AKT1_ST	Q96J02	ITCH	P31749	AKT1	S393	R395L	395	Missense	proximal	2	no	8.892	8.518	EPSD	ICGC	7.780	Down-regulation
AGC_Akt_AKT1_ST	Q96J02	ITCH	P31749	AKT1	S393	R388S	388	Missense	distal	-5	no	8.892	4.421	EPSD	ICGC	7.780	Loss
AGC_Akt_AKT1_ST	Q96J02	ITCH	P31749	AKT1	S393	E392D	392	Missense	proximal	-1	no	8.892	8.858	EPSD	ICGC	7.780	Down-regulation
AGC_Akt_AKT1_ST	Q96J02	ITCH	P31749	AKT1	S450	V454A	454	Missense	distal	4	no	12.364	12.308	EPSD	ICGC	7.780	Down-regulation
AGC_Akt_AKT1_ST	Q96J02	ITCH	P31749	AKT1	S450	G452C	452	Missense	proximal	2	no	12.364	11.872	EPSD	ICGC	7.780	Down-regulation
AGC_Akt_AKT1_ST	Q96J02	ITCH	P31749	AKT1	S450	G452V	452	Missense	proximal	2	no	12.364	12.158	EPSD	ICGC	7.780	Down-regulation
AGC_Akt_AKT1_ST	Q96J02	ITCH	P31749	AKT1	S450	K446N	446	Missense	distal	-4	no	12.364	11.725	EPSD	ICGC;COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	Q96J02	ITCH	P31749	AKT1	T504	N500S	500	Missense	distal	-4	no	12.659	13.226	EPSD	ICGC	7.780	Up-regulation
AGC_Akt_AKT1_ST	Q96J02	ITCH	P31749	AKT1	T504	V497L	497	Missense	distal	-7	no	12.659	12.703	EPSD	ICGC	7.780	Up-regulation
AGC_Akt_AKT1_ST	Q96J02	ITCH	P31749	AKT1	T504	I507V	507	Missense	distal	3	no	12.659	12.700	EPSD	ICGC;COSMIC	7.780	Up-regulation
AGC_Akt_AKT1_ST	Q96J02	ITCH	P31749	AKT1	T505	N500S	500	Missense	distal	-5	no	12.283	12.297	EPSD	ICGC	7.780	Up-regulation
AGC_Akt_AKT1_ST	Q96J02	ITCH	P31749	AKT1	T505	I507V	507	Missense	proximal	2	no	12.283	12.401	EPSD	ICGC;COSMIC	7.780	Up-regulation
AGC_Akt_AKT1_ST	O15360	FANCA	P31749	AKT1	T323	Q326L	326	Missense	distal	3	no	10.569	10.544	EPSD	ICGC;COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	O15360	FANCA	P31749	AKT1	S347	T351K	351	Missense	distal	4	no	10.908	10.890	EPSD	ICGC	7.780	Down-regulation
AGC_Akt_AKT1_ST	O15360	FANCA	P31749	AKT1	S581	L587M	587	Missense	distal	6	no	7.952	7.956	EPSD	ICGC	7.780	Up-regulation
AGC_Akt_AKT1_ST	O15360	FANCA	P31749	AKT1	S581	Y579C	579	Missense	proximal	-2	no	7.952	7.221	EPSD	ICGC;COSMIC	7.780	Loss
AGC_Akt_AKT1_ST	O15360	FANCA	P31749	AKT1	S581	H582P	582	Missense	proximal	1	no	7.952	7.974	EPSD	ICGC	7.780	Up-regulation
AGC_Akt_AKT1_ST	O15360	FANCA	P31749	AKT1	S1149	R1144L	1144	Missense	distal	-5	no	15.442	11.315	PhosphoSitePlus	ICGC;COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	O15360	FANCA	P31749	AKT1	S1191	R1184L	1184	Missense	distal	-7	no	10.292	10.002	EPSD	ICGC;COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	O15360	FANCA	P31749	AKT1	S1301	A1304T	1304	Missense	distal	3	no	13.469	13.526	EPSD	ICGC;COSMIC	7.780	Up-regulation
AGC_Akt_AKT1_ST	O15360	FANCA	P31749	AKT1	S1301	A1304E	1304	Missense	distal	3	no	13.469	13.485	EPSD	ICGC	7.780	Up-regulation
AGC_Akt_AKT1_ST	Q9BPZ7	MAPKAP1	P31749	AKT1	S84	R83L	83	Missense	proximal	-1	no	11.019	10.980	EPSD	ICGC;COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	Q9BPZ7	MAPKAP1	P31749	AKT1	S84	G79V	79	Missense	distal	-5	no	11.019	10.769	EPSD	ICGC;COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	Q9BPZ7	MAPKAP1	P31749	AKT1	T86	R92Q	92	Missense	distal	6	no	15.537	15.467	PhosphoSitePlus	ICGC;COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	Q9BPZ7	MAPKAP1	P31749	AKT1	T86	R83L	83	Missense	distal	-3	no	15.537	8.544	PhosphoSitePlus	ICGC;COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	Q9BPZ7	MAPKAP1	P31749	AKT1	T86	G79V	79	Missense	distal	-7	no	15.537	15.446	PhosphoSitePlus	ICGC;COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	P53602	MVD	P31749	AKT1	S96	P101L	101	Missense	distal	5	no	16.708	16.694	PhosphoSitePlus	ICGC;COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	P53602	MVD	P31749	AKT1	S96	P101R	101	Missense	distal	5	no	16.708	16.768	PhosphoSitePlus	ICGC;GDSC;CCLE	7.780	Up-regulation
AGC_Akt_AKT1_ST	P53602	MVD	P31749	AKT1	S96	G99V	99	Missense	distal	3	no	16.708	16.709	PhosphoSitePlus	ICGC;COSMIC	7.780	Up-regulation
AGC_Akt_AKT1_ST	P53602	MVD	P31749	AKT1	S96	R93L	93	Missense	distal	-3	no	16.708	9.714	PhosphoSitePlus	ICGC;COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	P53602	MVD	P31749	AKT1	S104	P101R	101	Missense	distal	-3	no	4.386	11.025	EPSD	ICGC;GDSC;CCLE	7.780	Gain
AGC_Akt_AKT1_ST	P53602	MVD	P31749	AKT1	S211	V213M	213	Missense	proximal	2	no	8.779	8.901	EPSD	ICGC	7.780	Up-regulation
AGC_Akt_AKT1_ST	P53602	MVD	P31749	AKT1	S211	L208M	208	Missense	distal	-3	no	8.779	8.268	EPSD	ICGC;COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	Q9BWT1	CDCA7	P31749	AKT1	S95	Q93K	93	Missense	proximal	-2	no	12.517	13.468	EPSD	ICGC	7.780	Up-regulation
AGC_Akt_AKT1_ST	Q9BWT1	CDCA7	P31749	AKT1	S95	R92H	92	Missense	distal	-3	no	12.517	7.818	EPSD	ICGC;COSMIC;CCLE	7.780	Down-regulation
AGC_Akt_AKT1_ST	Q9BWT1	CDCA7	P31749	AKT1	S95	P94S	94	Missense	proximal	-1	no	12.517	12.546	EPSD	ICGC;COSMIC	7.780	Up-regulation
AGC_Akt_AKT1_ST	Q9BWT1	CDCA7	P31749	AKT1	T163	R162H	162	Missense	proximal	-1	no	14.466	14.422	PhosphoSitePlus	ICGC;COSMIC;CCLE	7.780	Down-regulation
AGC_Akt_AKT1_ST	Q9BWT1	CDCA7	P31749	AKT1	T163	R160Q	160	Missense	distal	-3	no	14.466	7.255	PhosphoSitePlus	ICGC;COSMIC	7.780	Loss
AGC_Akt_AKT1_ST	Q9BWT1	CDCA7	P31749	AKT1	T163	R158I	158	Missense	distal	-5	no	14.466	9.899	PhosphoSitePlus	ICGC	7.780	Down-regulation
AGC_Akt_AKT1_ST	Q9BWT1	CDCA7	P31749	AKT1	T163	P165S	165	Missense	proximal	2	no	14.466	14.803	PhosphoSitePlus	ICGC;COSMIC	7.780	Up-regulation
AGC_Akt_AKT1_ST	Q9BWT1	CDCA7	P31749	AKT1	T163	R157M	157	Missense	distal	-6	no	14.466	14.370	PhosphoSitePlus	ICGC;COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	Q9BWT1	CDCA7	P31749	AKT1	T163	R161K	161	Missense	proximal	-2	no	14.466	14.906	PhosphoSitePlus	ICGC;COSMIC	7.780	Up-regulation
AGC_Akt_AKT1_ST	Q9BWT1	CDCA7	P31749	AKT1	S231	P236L	236	Missense	distal	5	no	11.194	11.181	EPSD	ICGC;COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	Q9BWT1	CDCA7	P31749	AKT1	S231	S231L	231	Missense	central	0	yes	11.194	0.000	EPSD	ICGC;COSMIC	7.780	Loss
AGC_Akt_AKT1_ST	Q9BWT1	CDCA7	P31749	AKT1	S231	R228H	228	Missense	distal	-3	no	11.194	6.495	EPSD	ICGC;COSMIC	7.780	Loss
AGC_Akt_AKT1_ST	Q9BWT1	CDCA7	P31749	AKT1	S231	R227H	227	Missense	distal	-4	no	11.194	10.135	EPSD	ICGC	7.780	Down-regulation
AGC_Akt_AKT1_ST	Q13185	CBX3	P31749	AKT1	S176	S176Y	176	Missense	central	0	yes	8.657	0.000	EPSD	ICGC;COSMIC	7.780	Loss
AGC_Akt_AKT1_ST	Q15942	ZYX	P31749	AKT1	S11	P4T	4	Missense	distal	-7	no	8.020	8.264	EPSD	ICGC;COSMIC	7.780	Up-regulation
AGC_Akt_AKT1_ST	Q15942	ZYX	P31749	AKT1	S143	S150F	150	Missense	distal	7	no	10.254	10.181	EPSD	ICGC;COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	Q15942	ZYX	P31749	AKT1	S143	P137L	137	Missense	distal	-6	no	10.254	10.268	EPSD	ICGC;COSMIC	7.780	Up-regulation
AGC_Akt_AKT1_ST	Q15942	ZYX	P31749	AKT1	S258	K265T	265	Missense	distal	7	no	8.170	8.180	EPSD	ICGC;COSMIC	7.780	Up-regulation
AGC_Akt_AKT1_ST	Q15942	ZYX	P31749	AKT1	S258	P260T	260	Missense	proximal	2	no	8.170	8.432	EPSD	ICGC;COSMIC	7.780	Up-regulation
AGC_Akt_AKT1_ST	Q15942	ZYX	P31749	AKT1	T480	V484M	484	Missense	distal	4	no	7.876	7.859	EPSD	ICGC;COSMIC;GDSC;CCLE	7.780	Down-regulation
AGC_Akt_AKT1_ST	Q15942	ZYX	P31749	AKT1	T480	C473S	473	Missense	distal	-7	no	7.876	8.299	EPSD	ICGC;COSMIC	7.780	Up-regulation
AGC_Akt_AKT1_ST	Q15942	ZYX	P31749	AKT1	T520	V521M	521	Missense	proximal	1	no	9.532	9.470	EPSD	ICGC;COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	Q15942	ZYX	P31749	AKT1	T520	R517L	517	Missense	distal	-3	no	9.532	2.538	EPSD	ICGC	7.780	Loss
AGC_Akt_AKT1_ST	Q9UNN5	FAF1	P31749	AKT1	S270	R268K	268	Missense	proximal	-2	no	13.035	13.475	EPSD	ICGC;COSMIC	7.780	Up-regulation
AGC_Akt_AKT1_ST	Q9UNN5	FAF1	P31749	AKT1	T580	T580N	580	Missense	central	0	yes	11.562	0.000	EPSD	ICGC;COSMIC	7.780	Loss
AGC_Akt_AKT1_ST	Q9UNN5	FAF1	P31749	AKT1	S582	R589C	589	Missense	distal	7	no	16.824	16.694	PhosphoSitePlus	ICGC;COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	Q9UNN5	FAF1	P31749	AKT1	S582	T580N	580	Missense	proximal	-2	no	16.824	16.205	PhosphoSitePlus	ICGC;COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	Q9UNN5	FAF1	P31749	AKT1	S582	R589S	589	Missense	distal	7	no	16.824	16.817	PhosphoSitePlus	ICGC	7.780	Down-regulation
AGC_Akt_AKT1_ST	Q9UNN5	FAF1	P31749	AKT1	S582	R588W	588	Missense	distal	6	no	16.824	16.666	PhosphoSitePlus	ICGC	7.780	Down-regulation
AGC_Akt_AKT1_ST	Q09472	EP300	P31749	AKT1	S19	S24L	24	Missense	distal	5	no	8.729	8.663	EPSD	ICGC;COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	Q09472	EP300	P31749	AKT1	S19	S12P	12	Missense	distal	-7	no	8.729	8.535	EPSD	ICGC;COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	Q09472	EP300	P31749	AKT1	S20	S24L	24	Missense	distal	4	no	11.821	12.009	EPSD	ICGC;COSMIC	7.780	Up-regulation
AGC_Akt_AKT1_ST	Q09472	EP300	P31749	AKT1	S89	L93F	93	Missense	distal	4	no	11.079	11.087	EPSD	ICGC	7.780	Up-regulation
AGC_Akt_AKT1_ST	Q09472	EP300	P31749	AKT1	S831	R838C	838	Missense	distal	7	no	8.571	8.442	EPSD	ICGC;COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	Q09472	EP300	P31749	AKT1	S831	L827R	827	Missense	distal	-4	no	8.571	9.781	EPSD	ICGC	7.780	Up-regulation
AGC_Akt_AKT1_ST	Q09472	EP300	P31749	AKT1	T841	R838C	838	Missense	distal	-3	no	10.699	4.526	EPSD	ICGC;COSMIC	7.780	Loss
AGC_Akt_AKT1_ST	Q09472	EP300	P31749	AKT1	S1037	P1039S	1039	Missense	proximal	2	no	7.589	7.925	EPSD	ICGC;COSMIC	7.780	Gain
AGC_Akt_AKT1_ST	Q09472	EP300	P31749	AKT1	S1072	E1071D	1071	Missense	proximal	-1	no	9.721	9.687	EPSD	ICGC;COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	Q09472	EP300	P31749	AKT1	T1190	R1187H	1187	Missense	distal	-3	no	8.801	4.102	EPSD	ICGC;COSMIC	7.780	Loss
AGC_Akt_AKT1_ST	Q09472	EP300	P31749	AKT1	S1734	D1729N	1729	Missense	distal	-5	no	12.320	11.882	EPSD	ICGC;COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	Q09472	EP300	P31749	AKT1	S1734	Q1740K	1740	Missense	distal	6	no	12.320	12.403	EPSD	ICGC;COSMIC	7.780	Up-regulation
AGC_Akt_AKT1_ST	Q09472	EP300	P31749	AKT1	S1834	R1829H	1829	Missense	distal	-5	no	16.157	13.062	PhosphoSitePlus	ICGC;COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	Q09472	EP300	P31749	AKT1	S1834	A1833T	1833	Missense	proximal	-1	no	16.157	16.183	PhosphoSitePlus	ICGC;COSMIC	7.780	Up-regulation
AGC_Akt_AKT1_ST	Q09472	EP300	P31749	AKT1	S1834	R1829L	1829	Missense	distal	-5	no	16.157	12.030	PhosphoSitePlus	ICGC	7.780	Down-regulation
AGC_Akt_AKT1_ST	Q09472	EP300	P31749	AKT1	S1834	R1831S	1831	Missense	distal	-3	no	16.157	8.380	PhosphoSitePlus	ICGC	7.780	Down-regulation
AGC_Akt_AKT1_ST	Q99623	PHB2	P31749	AKT1	T169	A172S	172	Missense	distal	3	no	10.513	10.571	EPSD	ICGC;COSMIC	7.780	Up-regulation
AGC_Akt_AKT1_ST	Q99623	PHB2	P31749	AKT1	S176	A172S	172	Missense	distal	-4	no	8.363	9.085	EPSD;PhosphoSitePlus	ICGC;COSMIC	7.780	Up-regulation
AGC_Akt_AKT1_ST	Q9UBP6	METTL1	P31749	AKT1	S27	H33N	33	Missense	distal	6	no	16.706	16.759	PhosphoSitePlus	ICGC;COSMIC	7.780	Up-regulation
AGC_Akt_AKT1_ST	Q9UBP6	METTL1	P31749	AKT1	S27	P29H	29	Missense	proximal	2	no	16.706	16.509	PhosphoSitePlus	ICGC;COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	Q9UBP6	METTL1	P31749	AKT1	S27	M30I	30	Missense	distal	3	no	16.706	16.660	PhosphoSitePlus	ICGC;COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	Q9UBP6	METTL1	P31749	AKT1	S177	T179N	179	Missense	proximal	2	no	12.435	12.241	EPSD	ICGC;COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	P17302	GJA1	P31749	AKT1	S244	D245V	245	Missense	proximal	1	no	11.197	11.409	EPSD	ICGC	7.780	Up-regulation
AGC_Akt_AKT1_ST	P17302	GJA1	P31749	AKT1	S244	A249V	249	Missense	distal	5	no	11.197	11.188	EPSD	ICGC;COSMIC;GDSC;CCLE	7.780	Down-regulation
AGC_Akt_AKT1_ST	P17302	GJA1	P31749	AKT1	S244	V240G	240	Missense	distal	-4	no	11.197	11.562	EPSD	ICGC;COSMIC	7.780	Up-regulation
AGC_Akt_AKT1_ST	P17302	GJA1	P31749	AKT1	S244	R239L	239	Missense	distal	-5	no	11.197	7.071	EPSD	ICGC;COSMIC	7.780	Loss
AGC_Akt_AKT1_ST	P17302	GJA1	P31749	AKT1	S244	V240L	240	Missense	distal	-4	no	11.197	11.167	EPSD	ICGC;COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	P17302	GJA1	P31749	AKT1	S244	G242R	242	Missense	proximal	-2	no	11.197	11.703	EPSD	ICGC;COSMIC;GDSC	7.780	Up-regulation
AGC_Akt_AKT1_ST	P17302	GJA1	P31749	AKT1	S296	K303N	303	Missense	distal	7	no	9.909	9.874	EPSD	ICGC	7.780	Down-regulation
AGC_Akt_AKT1_ST	P17302	GJA1	P31749	AKT1	S296	D292N	292	Missense	distal	-4	no	9.909	10.630	EPSD	ICGC	7.780	Up-regulation
AGC_Akt_AKT1_ST	P17302	GJA1	P31749	AKT1	S296	R293I	293	Missense	distal	-3	no	9.909	2.828	EPSD	ICGC	7.780	Loss
AGC_Akt_AKT1_ST	P17302	GJA1	P31749	AKT1	S296	T290N	290	Missense	distal	-6	no	9.909	9.831	EPSD	ICGC	7.780	Down-regulation
AGC_Akt_AKT1_ST	P17302	GJA1	P31749	AKT1	S296	T290I	290	Missense	distal	-6	no	9.909	9.758	EPSD	ICGC;COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	P17302	GJA1	P31749	AKT1	S296	V289L	289	Missense	distal	-7	no	9.909	9.953	EPSD	ICGC;COSMIC	7.780	Up-regulation
AGC_Akt_AKT1_ST	P17302	GJA1	P31749	AKT1	S306	Q304K	304	Missense	proximal	-2	no	7.263	8.215	EPSD	ICGC;COSMIC	7.780	Gain
AGC_Akt_AKT1_ST	P17302	GJA1	P31749	AKT1	S365	R362Q	362	Missense	distal	-3	no	13.378	6.166	EPSD	ICGC;COSMIC;GDSC	7.780	Loss
AGC_Akt_AKT1_ST	P17302	GJA1	P31749	AKT1	S365	D360E	360	Missense	distal	-5	no	13.378	13.328	EPSD	ICGC;COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	P17302	GJA1	P31749	AKT1	S365	R370H	370	Missense	distal	5	no	13.378	13.304	EPSD	ICGC;GDSC;CCLE	7.780	Down-regulation
AGC_Akt_AKT1_ST	P17302	GJA1	P31749	AKT1	S368	R362Q	362	Missense	distal	-6	no	7.958	7.874	EPSD	ICGC;COSMIC;GDSC	7.780	Down-regulation
AGC_Akt_AKT1_ST	P17302	GJA1	P31749	AKT1	S368	R370H	370	Missense	proximal	2	no	7.958	7.597	EPSD	ICGC;GDSC;CCLE	7.780	Loss
AGC_Akt_AKT1_ST	P17302	GJA1	P31749	AKT1	S369	R362Q	362	Missense	distal	-7	no	14.385	14.190	EPSD	ICGC;COSMIC;GDSC	7.780	Down-regulation
AGC_Akt_AKT1_ST	P17302	GJA1	P31749	AKT1	S369	R370H	370	Missense	proximal	1	no	14.385	14.062	EPSD	ICGC;GDSC;CCLE	7.780	Down-regulation
AGC_Akt_AKT1_ST	P17302	GJA1	P31749	AKT1	S372	D378N	378	Missense	distal	6	no	8.283	8.365	EPSD	ICGC	7.780	Up-regulation
AGC_Akt_AKT1_ST	P17302	GJA1	P31749	AKT1	S372	R370H	370	Missense	proximal	-2	no	8.283	7.423	EPSD	ICGC;GDSC;CCLE	7.780	Loss
AGC_Akt_AKT1_ST	P17302	GJA1	P31749	AKT1	S373	D378N	378	Missense	distal	5	no	14.796	14.836	PhosphoSitePlus	ICGC	7.780	Up-regulation
AGC_Akt_AKT1_ST	P17302	GJA1	P31749	AKT1	S373	R370H	370	Missense	distal	-3	no	14.796	10.097	PhosphoSitePlus	ICGC;GDSC;CCLE	7.780	Down-regulation
AGC_Akt_AKT1_ST	Q9H4X1	RGCC	P31749	AKT1	S64	D70H	70	Missense	distal	6	no	11.300	11.328	EPSD	ICGC	7.780	Up-regulation
AGC_Akt_AKT1_ST	Q9H4X1	RGCC	P31749	AKT1	S64	R62W	62	Missense	proximal	-2	no	11.300	10.046	EPSD	ICGC	7.780	Down-regulation
AGC_Akt_AKT1_ST	Q9H4X1	RGCC	P31749	AKT1	S64	S69I	69	Missense	distal	5	no	11.300	11.203	EPSD	ICGC;COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	Q9H4X1	RGCC	P31749	AKT1	S65	D70H	70	Missense	distal	5	no	12.435	12.444	EPSD	ICGC	7.780	Up-regulation
AGC_Akt_AKT1_ST	Q9H4X1	RGCC	P31749	AKT1	S65	R62W	62	Missense	distal	-3	no	12.435	3.495	EPSD	ICGC	7.780	Loss
AGC_Akt_AKT1_ST	Q9H4X1	RGCC	P31749	AKT1	S65	S69I	69	Missense	distal	4	no	12.435	12.697	EPSD	ICGC;COSMIC	7.780	Up-regulation
AGC_Akt_AKT1_ST	Q9H4X1	RGCC	P31749	AKT1	S67	D70H	70	Missense	distal	3	no	9.315	9.327	EPSD	ICGC	7.780	Up-regulation
AGC_Akt_AKT1_ST	Q9H4X1	RGCC	P31749	AKT1	S67	G73V	73	Missense	distal	6	no	9.315	9.307	EPSD	ICGC;COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	Q9H4X1	RGCC	P31749	AKT1	S67	R62W	62	Missense	distal	-5	no	9.315	3.795	EPSD	ICGC	7.780	Loss
AGC_Akt_AKT1_ST	Q9H4X1	RGCC	P31749	AKT1	S67	G73D	73	Missense	distal	6	no	9.315	9.271	EPSD	ICGC	7.780	Down-regulation
AGC_Akt_AKT1_ST	Q9H4X1	RGCC	P31749	AKT1	S67	S69I	69	Missense	proximal	2	no	9.315	8.659	EPSD	ICGC;COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	P06748	NPM1	P31749	AKT1	S48	A51S	51	Missense	distal	3	no	11.025	11.083	PhosphoSitePlus	ICGC	7.780	Up-regulation
AGC_Akt_AKT1_ST	P06748	NPM1	P31749	AKT1	S48	K54R	54	Missense	distal	6	no	11.025	11.014	PhosphoSitePlus	ICGC;COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	P06748	NPM1	P31749	AKT1	S48	Q41H	41	Missense	distal	-7	no	11.025	10.918	PhosphoSitePlus	ICGC	7.780	Down-regulation
AGC_Akt_AKT1_ST	P06748	NPM1	P31749	AKT1	S48	L42S	42	Missense	distal	-6	no	11.025	11.076	PhosphoSitePlus	ICGC;COSMIC	7.780	Up-regulation
AGC_Akt_AKT1_ST	P06748	NPM1	P31749	AKT1	T95	G90R	90	Missense	distal	-5	no	5.725	9.790	EPSD	ICGC;COSMIC	7.780	Gain
AGC_Akt_AKT1_ST	P06748	NPM1	P31749	AKT1	S106	V99L	99	Missense	distal	-7	no	9.646	9.690	EPSD	ICGC;COSMIC	7.780	Up-regulation
AGC_Akt_AKT1_ST	P06748	NPM1	P31749	AKT1	S106	L102F	102	Missense	distal	-4	no	9.646	9.603	EPSD	ICGC;COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	P06748	NPM1	P31749	AKT1	S106	S112I	112	Missense	distal	6	no	9.646	9.482	EPSD	ICGC	7.780	Down-regulation
AGC_Akt_AKT1_ST	P06748	NPM1	P31749	AKT1	S106	V99A	99	Missense	distal	-7	no	9.646	9.775	EPSD	ICGC;COSMIC	7.780	Up-regulation
AGC_Akt_AKT1_ST	Q92945	KHSRP	P31749	AKT1	T94	G89R	89	Missense	distal	-5	no	3.749	7.814	EPSD	ICGC	7.780	Gain
AGC_Akt_AKT1_ST	Q92945	KHSRP	P31749	AKT1	S193	T195K	195	Missense	proximal	2	no	13.425	13.516	PhosphoSitePlus	ICGC	7.780	Up-regulation
AGC_Akt_AKT1_ST	Q92945	KHSRP	P31749	AKT1	S193	S200Y	200	Missense	distal	7	no	13.425	13.382	PhosphoSitePlus	ICGC	7.780	Down-regulation
AGC_Akt_AKT1_ST	Q92945	KHSRP	P31749	AKT1	T195	T195K	195	Missense	central	0	yes	10.007	0.000	EPSD	ICGC	7.780	Loss
AGC_Akt_AKT1_ST	Q92945	KHSRP	P31749	AKT1	T195	S200Y	200	Missense	distal	5	no	10.007	9.964	EPSD	ICGC	7.780	Down-regulation
AGC_Akt_AKT1_ST	Q92945	KHSRP	P31749	AKT1	S319	G318R	318	Missense	proximal	-1	no	7.921	7.961	EPSD	ICGC;COSMIC	7.780	Up-regulation
AGC_Akt_AKT1_ST	Q92945	KHSRP	P31749	AKT1	S319	S319Y	319	Missense	central	0	yes	7.921	0.000	EPSD	ICGC;COSMIC	7.780	Loss
AGC_Akt_AKT1_ST	O60331	PIP5K1C	P31749	AKT1	T135	A140T	140	Missense	distal	5	no	9.425	9.476	EPSD	ICGC	7.780	Up-regulation
AGC_Akt_AKT1_ST	O60331	PIP5K1C	P31749	AKT1	S448	S449Y	449	Missense	proximal	1	no	12.315	12.308	EPSD	ICGC	7.780	Down-regulation
AGC_Akt_AKT1_ST	O60331	PIP5K1C	P31749	AKT1	S448	T442K	442	Missense	distal	-6	no	12.315	12.304	EPSD	ICGC;COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	O60331	PIP5K1C	P31749	AKT1	S448	S455P	455	Missense	distal	7	no	12.315	12.257	EPSD	ICGC;COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	O60331	PIP5K1C	P31749	AKT1	S449	S449Y	449	Missense	central	0	yes	9.630	0.000	EPSD	ICGC	7.780	Loss
AGC_Akt_AKT1_ST	O60331	PIP5K1C	P31749	AKT1	S449	T442K	442	Missense	distal	-7	no	9.630	9.622	EPSD	ICGC;COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	O60331	PIP5K1C	P31749	AKT1	S449	S455P	455	Missense	distal	6	no	9.630	9.537	EPSD	ICGC;COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	O60331	PIP5K1C	P31749	AKT1	S541	P536H	536	Missense	distal	-5	no	11.411	12.326	EPSD	ICGC	7.780	Up-regulation
AGC_Akt_AKT1_ST	O60331	PIP5K1C	P31749	AKT1	S541	S544L	544	Missense	distal	3	no	11.411	11.313	EPSD	ICGC;COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	O60331	PIP5K1C	P31749	AKT1	T543	P536H	536	Missense	distal	-7	no	10.500	10.449	EPSD	ICGC	7.780	Down-regulation
AGC_Akt_AKT1_ST	O60331	PIP5K1C	P31749	AKT1	T543	S544L	544	Missense	proximal	1	no	10.500	10.599	EPSD	ICGC;COSMIC	7.780	Up-regulation
AGC_Akt_AKT1_ST	O60331	PIP5K1C	P31749	AKT1	T553	T553A	553	Missense	central	0	yes	14.941	0.000	EPSD	ICGC	7.780	Loss
AGC_Akt_AKT1_ST	O60331	PIP5K1C	P31749	AKT1	S555	P562L	562	Missense	distal	7	no	16.291	16.283	PhosphoSitePlus	ICGC	7.780	Down-regulation
AGC_Akt_AKT1_ST	O60331	PIP5K1C	P31749	AKT1	S555	T553A	553	Missense	proximal	-2	no	16.291	15.906	PhosphoSitePlus	ICGC	7.780	Down-regulation
AGC_Akt_AKT1_ST	O60331	PIP5K1C	P31749	AKT1	S556	P562L	562	Missense	distal	6	no	8.805	8.795	EPSD	ICGC	7.780	Down-regulation
AGC_Akt_AKT1_ST	O60331	PIP5K1C	P31749	AKT1	S556	T553A	553	Missense	distal	-3	no	8.805	9.523	EPSD	ICGC	7.780	Up-regulation
AGC_Akt_AKT1_ST	O60331	PIP5K1C	P31749	AKT1	S650	W647L	647	Missense	distal	-3	no	7.851	9.798	EPSD	ICGC;COSMIC	7.780	Up-regulation
AGC_Akt_AKT1_ST	O60331	PIP5K1C	P31749	AKT1	S650	R645M	645	Missense	distal	-5	no	7.851	3.329	EPSD	ICGC;COSMIC	7.780	Loss
AGC_Akt_AKT1_ST	O60331	PIP5K1C	P31749	AKT1	S650	R645G	645	Missense	distal	-5	no	7.851	3.786	EPSD	ICGC;COSMIC;CCLE	7.780	Loss
AGC_Akt_AKT1_ST	Q12906	ILF3	P31749	AKT1	S384	K388N	388	Missense	distal	4	no	8.205	8.337	EPSD	ICGC;COSMIC	7.780	Up-regulation
AGC_Akt_AKT1_ST	Q12906	ILF3	P31749	AKT1	S384	K389N	389	Missense	distal	5	no	8.205	8.170	EPSD	ICGC	7.780	Down-regulation
AGC_Akt_AKT1_ST	Q12906	ILF3	P31749	AKT1	S477	G473V	473	Missense	distal	-4	no	11.456	11.091	EPSD	ICGC	7.780	Down-regulation
AGC_Akt_AKT1_ST	Q12906	ILF3	P31749	AKT1	S647	R640Q	640	Missense	distal	-7	no	16.183	15.988	PhosphoSitePlus	ICGC;COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	Q12906	ILF3	P31749	AKT1	S647	G646V	646	Missense	proximal	-1	no	16.183	16.178	PhosphoSitePlus	ICGC;COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	Q12906	ILF3	P31749	AKT1	S647	R651Q	651	Missense	distal	4	no	16.183	16.306	PhosphoSitePlus	ICGC;COSMIC	7.780	Up-regulation
AGC_Akt_AKT1_ST	Q12906	ILF3	P31749	AKT1	S765	S762R	762	Missense	distal	-3	no	3.530	11.306	EPSD	ICGC;COSMIC	7.780	Gain
AGC_Akt_AKT1_ST	Q12906	ILF3	P31749	AKT1	S820	G822C	822	Missense	proximal	2	no	8.780	8.287	EPSD	ICGC	7.780	Down-regulation
AGC_Akt_AKT1_ST	Q12906	ILF3	P31749	AKT1	S820	G822S	822	Missense	proximal	2	no	8.780	9.112	EPSD	ICGC;COSMIC	7.780	Up-regulation
AGC_Akt_AKT1_ST	Q12906	ILF3	P31749	AKT1	S820	S827F	827	Missense	distal	7	no	8.780	8.706	EPSD	ICGC	7.780	Down-regulation
AGC_Akt_AKT1_ST	Q12906	ILF3	P31749	AKT1	S888	A885T	885	Missense	distal	-3	no	10.394	9.676	EPSD	ICGC;CCLE	7.780	Down-regulation
AGC_Akt_AKT1_ST	Q8IYJ3	SYTL1	P31749	AKT1	S111	P118Q	118	Missense	distal	7	no	13.062	13.072	EPSD	ICGC;COSMIC	7.780	Up-regulation
AGC_Akt_AKT1_ST	Q8IYJ3	SYTL1	P31749	AKT1	T112	P118Q	118	Missense	distal	6	no	11.863	11.884	EPSD	ICGC;COSMIC	7.780	Up-regulation
AGC_Akt_AKT1_ST	Q8IYJ3	SYTL1	P31749	AKT1	S159	G154R	154	Missense	distal	-5	no	5.874	9.939	EPSD	ICGC	7.780	Gain
AGC_Akt_AKT1_ST	Q8WYL5	SSH1	P31749	AKT1	T11	S17L	17	Missense	distal	6	no	12.776	12.673	EPSD	ICGC	7.780	Down-regulation
AGC_Akt_AKT1_ST	Q8WYL5	SSH1	P31749	AKT1	T11	P12A	12	Missense	proximal	1	no	12.776	12.858	EPSD	ICGC;COSMIC	7.780	Up-regulation
AGC_Akt_AKT1_ST	Q8WYL5	SSH1	P31749	AKT1	S13	A19V	19	Missense	distal	6	no	11.720	11.688	EPSD	ICGC;COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	Q8WYL5	SSH1	P31749	AKT1	S13	S17L	17	Missense	distal	4	no	11.720	11.908	EPSD	ICGC	7.780	Up-regulation
AGC_Akt_AKT1_ST	Q8WYL5	SSH1	P31749	AKT1	S13	P12A	12	Missense	proximal	-1	no	11.720	11.728	EPSD	ICGC;COSMIC	7.780	Up-regulation
AGC_Akt_AKT1_ST	Q8WYL5	SSH1	P31749	AKT1	S37	D31N	31	Missense	distal	-6	no	9.289	9.360	EPSD	ICGC;COSMIC	7.780	Up-regulation
AGC_Akt_AKT1_ST	Q8WYL5	SSH1	P31749	AKT1	S37	D31H	31	Missense	distal	-6	no	9.289	9.323	EPSD	ICGC	7.780	Up-regulation
AGC_Akt_AKT1_ST	Q8WYL5	SSH1	P31749	AKT1	S237	K244R	244	Missense	distal	7	no	10.340	10.347	EPSD	ICGC;COSMIC	7.780	Up-regulation
AGC_Akt_AKT1_ST	Q8WYL5	SSH1	P31749	AKT1	S402	M395T	395	Missense	distal	-7	no	11.598	11.864	EPSD	ICGC;COSMIC	7.780	Up-regulation
AGC_Akt_AKT1_ST	Q8WYL5	SSH1	P31749	AKT1	S402	I405M	405	Missense	distal	3	no	11.598	11.644	EPSD	ICGC;COSMIC	7.780	Up-regulation
AGC_Akt_AKT1_ST	Q8WYL5	SSH1	P31749	AKT1	S402	A408E	408	Missense	distal	6	no	11.598	11.621	EPSD	ICGC	7.780	Up-regulation
AGC_Akt_AKT1_ST	Q8WYL5	SSH1	P31749	AKT1	S402	T403K	403	Missense	proximal	1	no	11.598	11.472	EPSD	ICGC	7.780	Down-regulation
AGC_Akt_AKT1_ST	Q8WYL5	SSH1	P31749	AKT1	S402	A401V	401	Missense	proximal	-1	no	11.598	11.584	EPSD	ICGC;COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	Q8WYL5	SSH1	P31749	AKT1	T430	K424E	424	Missense	distal	-6	no	12.426	12.360	EPSD	ICGC	7.780	Down-regulation
AGC_Akt_AKT1_ST	Q8WYL5	SSH1	P31749	AKT1	T430	R427L	427	Missense	distal	-3	no	12.426	5.432	EPSD	ICGC;COSMIC	7.780	Loss
AGC_Akt_AKT1_ST	Q8WYL5	SSH1	P31749	AKT1	T462	R459C	459	Missense	distal	-3	no	8.742	2.568	EPSD	ICGC;COSMIC	7.780	Loss
AGC_Akt_AKT1_ST	Q8WYL5	SSH1	P31749	AKT1	T462	D463E	463	Missense	proximal	1	no	8.742	8.859	EPSD	ICGC;COSMIC	7.780	Up-regulation
AGC_Akt_AKT1_ST	Q8WYL5	SSH1	P31749	AKT1	T462	R459S	459	Missense	distal	-3	no	8.742	0.965	EPSD	ICGC	7.780	Loss
AGC_Akt_AKT1_ST	Q8WYL5	SSH1	P31749	AKT1	T462	T462K	462	Missense	central	0	yes	8.742	0.000	EPSD	ICGC	7.780	Loss
AGC_Akt_AKT1_ST	Q8WYL5	SSH1	P31749	AKT1	T462	K456N	456	Missense	distal	-6	no	8.742	8.675	EPSD	ICGC;COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	Q8WYL5	SSH1	P31749	AKT1	S464	R459C	459	Missense	distal	-5	no	9.723	5.647	EPSD	ICGC;COSMIC	7.780	Loss
AGC_Akt_AKT1_ST	Q8WYL5	SSH1	P31749	AKT1	S464	D463E	463	Missense	proximal	-1	no	9.723	9.757	EPSD	ICGC;COSMIC	7.780	Up-regulation
AGC_Akt_AKT1_ST	Q8WYL5	SSH1	P31749	AKT1	S464	R459S	459	Missense	distal	-5	no	9.723	5.253	EPSD	ICGC	7.780	Loss
AGC_Akt_AKT1_ST	Q8WYL5	SSH1	P31749	AKT1	S464	T462K	462	Missense	proximal	-2	no	9.723	10.041	EPSD	ICGC	7.780	Up-regulation
AGC_Akt_AKT1_ST	Q8WYL5	SSH1	P31749	AKT1	S515	D516H	516	Missense	proximal	1	no	11.612	11.648	EPSD	ICGC;COSMIC	7.780	Up-regulation
AGC_Akt_AKT1_ST	Q8WYL5	SSH1	P31749	AKT1	S583	T590M	590	Missense	distal	7	no	14.261	14.192	EPSD	ICGC;COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	Q8WYL5	SSH1	P31749	AKT1	S696	P690T	690	Missense	distal	-6	no	8.131	8.226	EPSD	ICGC	7.780	Up-regulation
AGC_Akt_AKT1_ST	Q8WYL5	SSH1	P31749	AKT1	S696	L694F	694	Missense	proximal	-2	no	8.131	8.121	EPSD	ICGC;COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	Q8WYL5	SSH1	P31749	AKT1	S854	S849R	849	Missense	distal	-5	no	4.605	9.075	EPSD	ICGC;COSMIC	7.780	Gain
AGC_Akt_AKT1_ST	Q8WYL5	SSH1	P31749	AKT1	S937	S938R	938	Missense	proximal	1	no	13.058	13.203	EPSD	ICGC	7.780	Up-regulation
AGC_Akt_AKT1_ST	Q8WYL5	SSH1	P31749	AKT1	S937	H942N	942	Missense	distal	5	no	13.058	13.090	EPSD	ICGC	7.780	Up-regulation
AGC_Akt_AKT1_ST	Q8WYL5	SSH1	P31749	AKT1	T968	V969I	969	Missense	proximal	1	no	9.242	8.995	EPSD	ICGC;COSMIC;GDSC	7.780	Down-regulation
AGC_Akt_AKT1_ST	Q8WYL5	SSH1	P31749	AKT1	S978	H977Y	977	Missense	proximal	-1	no	12.062	12.070	EPSD	ICGC	7.780	Up-regulation
AGC_Akt_AKT1_ST	P35222	CTNNB1	P31749	AKT1	T332	T332N	332	Missense	central	0	yes	11.856	0.000	EPSD	ICGC;COSMIC	7.780	Loss
AGC_Akt_AKT1_ST	P35222	CTNNB1	P31749	AKT1	T547	R542C	542	Missense	distal	-5	no	9.356	5.279	EPSD	ICGC;COSMIC	7.780	Loss
AGC_Akt_AKT1_ST	P35222	CTNNB1	P31749	AKT1	S715	R710H	710	Missense	distal	-5	no	9.638	6.543	EPSD	ICGC;COSMIC	7.780	Loss
AGC_Akt_AKT1_ST	P54274	TERF1	P31749	AKT1	S11	D4N	4	Missense	distal	-7	no	7.686	7.944	EPSD	ICGC;COSMIC	7.780	Gain
AGC_Akt_AKT1_ST	P54274	TERF1	P31749	AKT1	S11	A9S	9	Missense	proximal	-2	no	7.686	8.138	EPSD	ICGC;COSMIC	7.780	Gain
AGC_Akt_AKT1_ST	P54274	TERF1	P31749	AKT1	T24	D22N	22	Missense	proximal	-2	no	7.866	8.573	EPSD	ICGC;COSMIC	7.780	Up-regulation
AGC_Akt_AKT1_ST	P54274	TERF1	P31749	AKT1	T24	E26K	26	Missense	proximal	2	no	7.866	8.071	EPSD	ICGC	7.780	Up-regulation
AGC_Akt_AKT1_ST	P54274	TERF1	P31749	AKT1	T24	G18N	18	Missense	distal	-6	no	7.866	7.898	EPSD	ICGC	7.780	Up-regulation
AGC_Akt_AKT1_ST	P54274	TERF1	P31749	AKT1	T24	D17N	17	Missense	distal	-7	no	7.866	8.123	EPSD	ICGC;GDSC;CCLE	7.780	Up-regulation
AGC_Akt_AKT1_ST	P54274	TERF1	P31749	AKT1	T271	I272L	272	Missense	proximal	1	no	10.789	11.136	EPSD	ICGC;COSMIC	7.780	Up-regulation
AGC_Akt_AKT1_ST	P54274	TERF1	P31749	AKT1	T273	S279N	279	Missense	distal	6	no	15.133	15.066	PhosphoSitePlus	ICGC;COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	P54274	TERF1	P31749	AKT1	T273	I272L	272	Missense	proximal	-1	no	15.133	15.154	PhosphoSitePlus	ICGC;COSMIC	7.780	Up-regulation
AGC_Akt_AKT1_ST	Q86VP3	PACS2	P31749	AKT1	S43	T45P	45	Missense	proximal	2	no	11.944	11.682	EPSD	ICGC;COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	Q86VP3	PACS2	P31749	AKT1	S43	L44M	44	Missense	proximal	1	no	11.944	11.782	EPSD	ICGC;COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	Q86VP3	PACS2	P31749	AKT1	T125	R118H	118	Missense	distal	-7	no	10.903	10.602	EPSD	ICGC	7.780	Down-regulation
AGC_Akt_AKT1_ST	Q86VP3	PACS2	P31749	AKT1	T125	R118C	118	Missense	distal	-7	no	10.903	10.424	EPSD	ICGC	7.780	Down-regulation
AGC_Akt_AKT1_ST	Q99490	AGAP2	P31749	AKT1	S146	R141P	141	Missense	distal	-5	no	10.152	6.142	EPSD	ICGC	7.780	Loss
AGC_Akt_AKT1_ST	Q99490	AGAP2	P31749	AKT1	S146	S147C	147	Missense	proximal	1	no	10.152	9.769	EPSD	ICGC;COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	Q99490	AGAP2	P31749	AKT1	S147	R141P	141	Missense	distal	-6	no	8.810	8.712	EPSD	ICGC	7.780	Down-regulation
AGC_Akt_AKT1_ST	Q99490	AGAP2	P31749	AKT1	S147	S147C	147	Missense	central	0	yes	8.810	0.000	EPSD	ICGC;COSMIC	7.780	Loss
AGC_Akt_AKT1_ST	Q99490	AGAP2	P31749	AKT1	S648	R653S	653	Missense	distal	5	no	13.167	13.159	EPSD	ICGC;COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	Q99490	AGAP2	P31749	AKT1	S656	R653S	653	Missense	distal	-3	no	11.284	3.508	EPSD	ICGC;COSMIC	7.780	Loss
AGC_Akt_AKT1_ST	Q99490	AGAP2	P31749	AKT1	S745	R739Q	739	Missense	distal	-6	no	10.502	10.418	EPSD	ICGC;COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	Q99490	AGAP2	P31749	AKT1	S821	S818R	818	Missense	distal	-3	no	3.018	10.795	EPSD	ICGC	7.780	Gain
AGC_Akt_AKT1_ST	Q99490	AGAP2	P31749	AKT1	T839	S842F	842	Missense	distal	3	no	11.095	10.996	EPSD	ICGC	7.780	Down-regulation
AGC_Akt_AKT1_ST	Q99490	AGAP2	P31749	AKT1	S985	P992T	992	Missense	distal	7	no	11.831	11.899	EPSD	ICGC	7.780	Up-regulation
AGC_Akt_AKT1_ST	Q8N6T7	SIRT6	P31749	AKT1	T167	T162R	162	Missense	distal	-5	no	10.227	13.956	EPSD	ICGC;COSMIC	7.780	Up-regulation
AGC_Akt_AKT1_ST	Q8N6T7	SIRT6	P31749	AKT1	T294	T294P	294	Missense	central	0	yes	10.514	0.000	EPSD	ICGC;COSMIC	7.780	Loss
AGC_Akt_AKT1_ST	Q8N6T7	SIRT6	P31749	AKT1	T294	R291P	291	Missense	distal	-3	no	10.514	3.874	EPSD	ICGC;COSMIC	7.780	Loss
AGC_Akt_AKT1_ST	Q8N6T7	SIRT6	P31749	AKT1	T294	E301D	301	Missense	distal	7	no	10.514	10.471	EPSD	ICGC;COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	Q8N6T7	SIRT6	P31749	AKT1	T294	L289P	289	Missense	distal	-5	no	10.514	10.630	EPSD	ICGC;COSMIC	7.780	Up-regulation
AGC_Akt_AKT1_ST	Q8N6T7	SIRT6	P31749	AKT1	T337	P336S	336	Missense	proximal	-1	no	7.818	7.847	EPSD	ICGC	7.780	Up-regulation
AGC_Akt_AKT1_ST	Q8N6T7	SIRT6	P31749	AKT1	T337	R335Q	335	Missense	proximal	-2	no	7.818	7.306	EPSD	ICGC	7.780	Loss
AGC_Akt_AKT1_ST	Q8N6T7	SIRT6	P31749	AKT1	T337	H342N	342	Missense	distal	5	no	7.818	7.850	EPSD	ICGC	7.780	Up-regulation
AGC_Akt_AKT1_ST	Q8N6T7	SIRT6	P31749	AKT1	T337	S338R	338	Missense	proximal	1	no	7.818	7.963	EPSD	ICGC	7.780	Up-regulation
AGC_Akt_AKT1_ST	Q8N6T7	SIRT6	P31749	AKT1	T337	P339T	339	Missense	proximal	2	no	7.818	8.080	EPSD	ICGC	7.780	Up-regulation
AGC_Akt_AKT1_ST	Q8N6T7	SIRT6	P31749	AKT1	S338	P336S	336	Missense	proximal	-2	no	17.700	18.525	PhosphoSitePlus	ICGC	7.780	Up-regulation
AGC_Akt_AKT1_ST	Q8N6T7	SIRT6	P31749	AKT1	S338	R335Q	335	Missense	distal	-3	no	17.700	10.489	PhosphoSitePlus	ICGC	7.780	Down-regulation
AGC_Akt_AKT1_ST	Q8N6T7	SIRT6	P31749	AKT1	S338	H342N	342	Missense	distal	4	no	17.700	17.614	PhosphoSitePlus	ICGC	7.780	Down-regulation
AGC_Akt_AKT1_ST	Q8N6T7	SIRT6	P31749	AKT1	S338	S338R	338	Missense	central	0	yes	17.700	0.000	PhosphoSitePlus	ICGC	7.780	Loss
AGC_Akt_AKT1_ST	Q8N6T7	SIRT6	P31749	AKT1	S338	P339T	339	Missense	proximal	1	no	17.700	18.049	PhosphoSitePlus	ICGC	7.780	Up-regulation
AGC_Akt_AKT1_ST	O14746	TERT	P31749	AKT1	T618	T618K	618	Missense	central	0	yes	8.229	0.000	EPSD	ICGC	7.780	Loss
AGC_Akt_AKT1_ST	O14746	TERT	P31749	AKT1	T618	L616M	616	Missense	proximal	-2	no	8.229	8.246	EPSD	ICGC	7.780	Up-regulation
AGC_Akt_AKT1_ST	O14746	TERT	P31749	AKT1	T618	F623L	623	Missense	distal	5	no	8.229	8.235	EPSD	ICGC;COSMIC	7.780	Up-regulation
AGC_Akt_AKT1_ST	O14746	TERT	P31749	AKT1	T618	L621I	621	Missense	distal	3	no	8.229	8.196	EPSD	ICGC;COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	O14746	TERT	P31749	AKT1	S824	G830V	830	Missense	distal	6	no	14.874	14.866	EPSD;PhosphoSitePlus	ICGC;COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	O14746	TERT	P31749	AKT1	S824	V818M	818	Missense	distal	-6	no	14.874	14.888	EPSD;PhosphoSitePlus	ICGC;COSMIC	7.780	Up-regulation
AGC_Akt_AKT1_ST	O14746	TERT	P31749	AKT1	S824	S824F	824	Missense	central	0	yes	14.874	0.000	EPSD;PhosphoSitePlus	ICGC;COSMIC	7.780	Loss
AGC_Akt_AKT1_ST	O14746	TERT	P31749	AKT1	S824	A817T	817	Missense	distal	-7	no	14.874	15.074	EPSD;PhosphoSitePlus	ICGC;COSMIC	7.780	Up-regulation
AGC_Akt_AKT1_ST	O14746	TERT	P31749	AKT1	S824	G830W	830	Missense	distal	6	no	14.874	14.820	EPSD;PhosphoSitePlus	ICGC;COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	O14746	TERT	P31749	AKT1	S824	R821S	821	Missense	distal	-3	no	14.874	7.098	EPSD;PhosphoSitePlus	ICGC;COSMIC	7.780	Loss
AGC_Akt_AKT1_ST	O14746	TERT	P31749	AKT1	S824	Q829R	829	Missense	distal	5	no	14.874	14.925	EPSD;PhosphoSitePlus	ICGC;COSMIC	7.780	Up-regulation
AGC_Akt_AKT1_ST	P21453	S1PR1	P31749	AKT1	T236	R231Q	231	Missense	distal	-5	no	16.477	12.250	PhosphoSitePlus	ICGC;COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	P21453	S1PR1	P31749	AKT1	S355	R352C	352	Missense	distal	-3	no	13.849	7.675	EPSD	ICGC	7.780	Loss
AGC_Akt_AKT1_ST	P21453	S1PR1	P31749	AKT1	S355	S359C	359	Missense	distal	4	no	13.849	14.194	EPSD	ICGC;COSMIC	7.780	Up-regulation
AGC_Akt_AKT1_ST	P46937	YAP1	P31749	AKT1	S94	P99Q	99	Missense	distal	5	no	8.520	8.530	EPSD	ICGC;COSMIC	7.780	Up-regulation
AGC_Akt_AKT1_ST	P46937	YAP1	P31749	AKT1	S105	P99Q	99	Missense	distal	-6	no	8.034	8.048	EPSD	ICGC;COSMIC	7.780	Up-regulation
AGC_Akt_AKT1_ST	P46937	YAP1	P31749	AKT1	S109	T110S	110	Missense	proximal	1	no	13.488	13.295	EPSD	ICGC;COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	P46937	YAP1	P31749	AKT1	S109	A115T	115	Missense	distal	6	no	13.488	13.591	EPSD	ICGC	7.780	Up-regulation
AGC_Akt_AKT1_ST	P46937	YAP1	P31749	AKT1	S127	Q133L	133	Missense	distal	6	no	11.042	11.010	PhosphoSitePlus	ICGC;COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	P46937	YAP1	P31749	AKT1	S127	V123F	123	Missense	distal	-4	no	11.042	10.968	PhosphoSitePlus	ICGC	7.780	Down-regulation
AGC_Akt_AKT1_ST	P46937	YAP1	P31749	AKT1	S127	L134F	134	Missense	distal	7	no	11.042	11.034	PhosphoSitePlus	ICGC;COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	P46937	YAP1	P31749	AKT1	S127	H126R	126	Missense	proximal	-1	no	11.042	11.086	PhosphoSitePlus	ICGC;COSMIC	7.780	Up-regulation
AGC_Akt_AKT1_ST	P46937	YAP1	P31749	AKT1	S164	D169N	169	Missense	distal	5	no	11.562	11.602	EPSD	ICGC;COSMIC	7.780	Up-regulation
AGC_Akt_AKT1_ST	P46937	YAP1	P31749	AKT1	S164	S163F	163	Missense	proximal	-1	no	11.562	11.528	EPSD	ICGC;COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	P46937	YAP1	P31749	AKT1	S164	V171A	171	Missense	distal	7	no	11.562	11.566	EPSD	ICGC;COSMIC	7.780	Up-regulation
AGC_Akt_AKT1_ST	P46937	YAP1	P31749	AKT1	S164	R161L	161	Missense	distal	-3	no	11.562	4.568	EPSD	ICGC	7.780	Loss
AGC_Akt_AKT1_ST	P46937	YAP1	P31749	AKT1	S164	S164F	164	Missense	central	0	yes	11.562	0.000	EPSD	ICGC	7.780	Loss
AGC_Akt_AKT1_ST	P46937	YAP1	P31749	AKT1	S257	R262S	262	Missense	distal	5	no	9.146	9.138	EPSD	ICGC	7.780	Down-regulation
AGC_Akt_AKT1_ST	P46937	YAP1	P31749	AKT1	S257	P261Q	261	Missense	distal	4	no	9.146	9.124	EPSD	ICGC;COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	P46937	YAP1	P31749	AKT1	S257	L259I	259	Missense	proximal	2	no	9.146	9.035	EPSD	ICGC;COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	P46937	YAP1	P31749	AKT1	T378	Q372R	372	Missense	distal	-6	no	9.656	9.741	EPSD	ICGC;COSMIC	7.780	Up-regulation
AGC_Akt_AKT1_ST	P46937	YAP1	P31749	AKT1	T378	F385S	385	Missense	distal	7	no	9.656	9.730	EPSD	ICGC	7.780	Up-regulation
AGC_Akt_AKT1_ST	P46937	YAP1	P31749	AKT1	T378	Q372K	372	Missense	distal	-6	no	9.656	9.726	EPSD	ICGC;COSMIC	7.780	Up-regulation
AGC_Akt_AKT1_ST	P46937	YAP1	P31749	AKT1	S397	L402P	402	Missense	distal	5	no	12.580	12.593	EPSD	ICGC;COSMIC	7.780	Up-regulation
AGC_Akt_AKT1_ST	P46937	YAP1	P31749	AKT1	S397	R394Q	394	Missense	distal	-3	no	12.580	5.369	EPSD	ICGC;COSMIC	7.780	Loss
AGC_Akt_AKT1_ST	P46937	YAP1	P31749	AKT1	S397	S397I	397	Missense	central	0	yes	12.580	0.000	EPSD	ICGC	7.780	Loss
AGC_Akt_AKT1_ST	P46937	YAP1	P31749	AKT1	S397	H392N	392	Missense	distal	-5	no	12.580	11.190	EPSD	ICGC;COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	P46937	YAP1	P31749	AKT1	S397	T398A	398	Missense	proximal	1	no	12.580	12.313	EPSD	ICGC;COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	P46937	YAP1	P31749	AKT1	S499	T493A	493	Missense	distal	-6	no	9.760	9.674	EPSD	ICGC;COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	Q9H9Q4	NHEJ1	P31749	AKT1	T181	P183T	183	Missense	proximal	2	no	13.742	14.004	PhosphoSitePlus	ICGC	7.780	Up-regulation
AGC_Akt_AKT1_ST	Q9NWV8	BABAM1	P31749	AKT1	T27	R28S	28	Missense	proximal	1	no	11.107	10.963	EPSD	ICGC;COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	Q9NWV8	BABAM1	P31749	AKT1	T27	A34G	34	Missense	distal	7	no	11.107	11.085	EPSD	ICGC;COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	Q9NWV8	BABAM1	P31749	AKT1	S29	R28S	28	Missense	proximal	-1	no	15.557	15.546	PhosphoSitePlus	ICGC;COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	Q9NWV8	BABAM1	P31749	AKT1	S29	A34G	34	Missense	distal	5	no	15.557	15.545	PhosphoSitePlus	ICGC;COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	Q9NWV8	BABAM1	P31749	AKT1	S116	A120T	120	Missense	distal	4	no	8.098	7.969	EPSD	ICGC;COSMIC;CCLE	7.780	Down-regulation
AGC_Akt_AKT1_ST	Q9NWV8	BABAM1	P31749	AKT1	S116	A120S	120	Missense	distal	4	no	8.098	7.974	EPSD	ICGC	7.780	Down-regulation
AGC_Akt_AKT1_ST	Q9NWV8	BABAM1	P31749	AKT1	S116	G115V	115	Missense	proximal	-1	no	8.098	8.093	EPSD	ICGC;COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	Q86TI0	TBC1D1	P31749	AKT1	S224	P221H	221	Missense	distal	-3	no	6.621	8.562	EPSD	ICGC	7.780	Gain
AGC_Akt_AKT1_ST	Q86TI0	TBC1D1	P31749	AKT1	S235	R233C	233	Missense	proximal	-2	no	8.951	7.487	EPSD	ICGC	7.780	Loss
AGC_Akt_AKT1_ST	Q86TI0	TBC1D1	P31749	AKT1	S235	V228G	228	Missense	distal	-7	no	8.951	9.043	EPSD	ICGC;COSMIC	7.780	Up-regulation
AGC_Akt_AKT1_ST	Q86TI0	TBC1D1	P31749	AKT1	S235	P231S	231	Missense	distal	-4	no	8.951	9.688	EPSD	ICGC	7.780	Up-regulation
AGC_Akt_AKT1_ST	Q86TI0	TBC1D1	P31749	AKT1	S235	R229C	229	Missense	distal	-6	no	8.951	8.771	EPSD	ICGC	7.780	Down-regulation
AGC_Akt_AKT1_ST	Q86TI0	TBC1D1	P31749	AKT1	S235	S237P	237	Missense	proximal	2	no	8.951	8.615	EPSD	ICGC;COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	Q86TI0	TBC1D1	P31749	AKT1	S237	R233C	233	Missense	distal	-4	no	9.224	7.546	EPSD	ICGC	7.780	Loss
AGC_Akt_AKT1_ST	Q86TI0	TBC1D1	P31749	AKT1	S237	P231S	231	Missense	distal	-6	no	9.224	9.288	EPSD	ICGC	7.780	Up-regulation
AGC_Akt_AKT1_ST	Q86TI0	TBC1D1	P31749	AKT1	S237	S237P	237	Missense	central	0	yes	9.224	0.000	EPSD	ICGC;COSMIC	7.780	Loss
AGC_Akt_AKT1_ST	Q86TI0	TBC1D1	P31749	AKT1	T294	R289L	289	Missense	distal	-5	no	8.234	4.108	EPSD	ICGC;COSMIC	7.780	Loss
AGC_Akt_AKT1_ST	Q86TI0	TBC1D1	P31749	AKT1	T294	I295S	295	Missense	proximal	1	no	8.234	8.482	EPSD	ICGC	7.780	Up-regulation
AGC_Akt_AKT1_ST	Q86TI0	TBC1D1	P31749	AKT1	T505	K501E	501	Missense	distal	-4	no	12.351	11.767	EPSD	ICGC;COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	Q86TI0	TBC1D1	P31749	AKT1	S507	S513F	513	Missense	distal	6	no	9.996	9.876	EPSD	ICGC	7.780	Down-regulation
AGC_Akt_AKT1_ST	Q86TI0	TBC1D1	P31749	AKT1	S507	K501E	501	Missense	distal	-6	no	9.996	9.930	EPSD	ICGC;COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	Q86TI0	TBC1D1	P31749	AKT1	T596	R593Q	593	Missense	distal	-3	no	15.087	7.876	PhosphoSitePlus	ICGC;COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	Q86TI0	TBC1D1	P31749	AKT1	S598	R593Q	593	Missense	distal	-5	no	7.836	3.608	EPSD	ICGC;COSMIC	7.780	Loss
AGC_Akt_AKT1_ST	Q86TI0	TBC1D1	P31749	AKT1	S627	T632M	632	Missense	distal	5	no	11.603	11.546	EPSD	ICGC	7.780	Down-regulation
AGC_Akt_AKT1_ST	Q86TI0	TBC1D1	P31749	AKT1	S627	M623L	623	Missense	distal	-4	no	11.603	11.388	EPSD	ICGC	7.780	Down-regulation
AGC_Akt_AKT1_ST	Q86TI0	TBC1D1	P31749	AKT1	S629	T632M	632	Missense	distal	3	no	11.727	11.643	EPSD	ICGC	7.780	Down-regulation
AGC_Akt_AKT1_ST	Q86TI0	TBC1D1	P31749	AKT1	S629	M623L	623	Missense	distal	-6	no	11.727	11.739	EPSD	ICGC	7.780	Up-regulation
AGC_Akt_AKT1_ST	Q86TI0	TBC1D1	P31749	AKT1	S660	L667F	667	Missense	distal	7	no	15.256	15.249	EPSD	ICGC;COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	Q86TI0	TBC1D1	P31749	AKT1	T671	L667F	667	Missense	distal	-4	no	10.768	10.724	EPSD	ICGC;COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	Q86TI0	TBC1D1	P31749	AKT1	S686	S679F	679	Missense	distal	-7	no	8.135	7.857	EPSD	ICGC	7.780	Down-regulation
AGC_Akt_AKT1_ST	Q86TI0	TBC1D1	P31749	AKT1	T716	P709S	709	Missense	distal	-7	no	8.197	8.391	EPSD	ICGC;COSMIC	7.780	Up-regulation
AGC_Akt_AKT1_ST	Q86TI0	TBC1D1	P31749	AKT1	T716	L723M	723	Missense	distal	7	no	8.197	8.204	EPSD	ICGC;COSMIC	7.780	Up-regulation
AGC_Akt_AKT1_ST	Q86TI0	TBC1D1	P31749	AKT1	S717	L723M	723	Missense	distal	6	no	8.913	8.918	EPSD	ICGC;COSMIC	7.780	Up-regulation
AGC_Akt_AKT1_ST	Q86TI0	TBC1D1	P31749	AKT1	S1150	D1155N	1155	Missense	distal	5	no	11.421	11.462	EPSD	ICGC;COSMIC	7.780	Up-regulation
AGC_Akt_AKT1_ST	Q86TI0	TBC1D1	P31749	AKT1	S1150	R1149Q	1149	Missense	proximal	-1	no	11.421	11.389	EPSD	ICGC	7.780	Down-regulation
AGC_Akt_AKT1_ST	Q86TI0	TBC1D1	P31749	AKT1	S1154	D1155N	1155	Missense	proximal	1	no	11.797	11.921	EPSD	ICGC;COSMIC	7.780	Up-regulation
AGC_Akt_AKT1_ST	Q86TI0	TBC1D1	P31749	AKT1	S1154	R1149Q	1149	Missense	distal	-5	no	11.797	7.569	EPSD	ICGC	7.780	Loss
AGC_Akt_AKT1_ST	Q9Y2I7	PIKFYVE	P31749	AKT1	T10	T7K	7	Missense	distal	-3	no	6.837	9.338	EPSD	ICGC;COSMIC	7.780	Gain
AGC_Akt_AKT1_ST	Q9Y2I7	PIKFYVE	P31749	AKT1	S85	S81L	81	Missense	distal	-4	no	12.329	11.205	EPSD	ICGC;COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	Q9Y2I7	PIKFYVE	P31749	AKT1	S105	K112T	112	Missense	distal	7	no	10.955	10.965	EPSD	ICGC;COSMIC	7.780	Up-regulation
AGC_Akt_AKT1_ST	Q9Y2I7	PIKFYVE	P31749	AKT1	S105	R102Q	102	Missense	distal	-3	no	10.955	3.744	EPSD	ICGC	7.780	Loss
AGC_Akt_AKT1_ST	Q9Y2I7	PIKFYVE	P31749	AKT1	S219	A221V	221	Missense	proximal	2	no	9.673	9.511	EPSD	ICGC	7.780	Down-regulation
AGC_Akt_AKT1_ST	Q9Y2I7	PIKFYVE	P31749	AKT1	S291	V292L	292	Missense	proximal	1	no	11.762	11.861	EPSD	ICGC	7.780	Up-regulation
AGC_Akt_AKT1_ST	Q9Y2I7	PIKFYVE	P31749	AKT1	S291	V290L	290	Missense	proximal	-1	no	11.762	11.768	EPSD	ICGC	7.780	Up-regulation
AGC_Akt_AKT1_ST	Q9Y2I7	PIKFYVE	P31749	AKT1	S305	L311M	311	Missense	distal	6	no	11.406	11.411	EPSD	ICGC	7.780	Up-regulation
AGC_Akt_AKT1_ST	Q9Y2I7	PIKFYVE	P31749	AKT1	S305	N310T	310	Missense	distal	5	no	11.406	11.441	EPSD	ICGC;COSMIC	7.780	Up-regulation
AGC_Akt_AKT1_ST	Q9Y2I7	PIKFYVE	P31749	AKT1	S305	R302Q	302	Missense	distal	-3	no	11.406	4.195	EPSD	ICGC;COSMIC	7.780	Loss
AGC_Akt_AKT1_ST	Q9Y2I7	PIKFYVE	P31749	AKT1	S307	L311M	311	Missense	distal	4	no	16.554	16.529	EPSD;PhosphoSitePlus	ICGC	7.780	Down-regulation
AGC_Akt_AKT1_ST	Q9Y2I7	PIKFYVE	P31749	AKT1	S307	N310T	310	Missense	distal	3	no	16.554	16.610	EPSD;PhosphoSitePlus	ICGC;COSMIC	7.780	Up-regulation
AGC_Akt_AKT1_ST	Q9Y2I7	PIKFYVE	P31749	AKT1	S307	R302Q	302	Missense	distal	-5	no	16.554	12.327	EPSD;PhosphoSitePlus	ICGC;COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	Q9Y2I7	PIKFYVE	P31749	AKT1	T309	L311M	311	Missense	proximal	2	no	8.235	8.364	EPSD	ICGC	7.780	Up-regulation
AGC_Akt_AKT1_ST	Q9Y2I7	PIKFYVE	P31749	AKT1	T309	N310T	310	Missense	proximal	1	no	8.235	8.516	EPSD	ICGC;COSMIC	7.780	Up-regulation
AGC_Akt_AKT1_ST	Q9Y2I7	PIKFYVE	P31749	AKT1	T309	R302Q	302	Missense	distal	-7	no	8.235	8.040	EPSD	ICGC;COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	Q9Y2I7	PIKFYVE	P31749	AKT1	S318	M320I	320	Missense	proximal	2	no	11.141	10.901	PhosphoSitePlus;EPSD	ICGC;COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	Q9Y2I7	PIKFYVE	P31749	AKT1	S318	L311M	311	Missense	distal	-7	no	11.141	11.158	PhosphoSitePlus;EPSD	ICGC	7.780	Up-regulation
AGC_Akt_AKT1_ST	Q9Y2I7	PIKFYVE	P31749	AKT1	S318	G317C	317	Missense	proximal	-1	no	11.141	11.110	PhosphoSitePlus;EPSD	ICGC;COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	Q9Y2I7	PIKFYVE	P31749	AKT1	T341	R346H	346	Missense	distal	5	no	9.937	9.863	EPSD	ICGC;COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	Q9Y2I7	PIKFYVE	P31749	AKT1	T341	R346C	346	Missense	distal	5	no	9.937	9.811	EPSD	ICGC;COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	Q9Y2I7	PIKFYVE	P31749	AKT1	S499	R497H	497	Missense	proximal	-2	no	9.990	9.129	EPSD	ICGC;COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	Q9Y2I7	PIKFYVE	P31749	AKT1	S499	V500I	500	Missense	proximal	1	no	9.990	9.743	EPSD	ICGC;COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	Q9Y2I7	PIKFYVE	P31749	AKT1	S499	S495I	495	Missense	distal	-4	no	9.990	8.609	EPSD	ICGC;COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	Q9Y2I7	PIKFYVE	P31749	AKT1	S499	V500F	500	Missense	proximal	1	no	9.990	10.009	EPSD	ICGC	7.780	Up-regulation
AGC_Akt_AKT1_ST	Q9Y2I7	PIKFYVE	P31749	AKT1	S501	R497H	497	Missense	distal	-4	no	8.102	7.043	EPSD	ICGC;COSMIC	7.780	Loss
AGC_Akt_AKT1_ST	Q9Y2I7	PIKFYVE	P31749	AKT1	S501	V500I	500	Missense	proximal	-1	no	8.102	8.087	EPSD	ICGC;COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	Q9Y2I7	PIKFYVE	P31749	AKT1	S501	S495I	495	Missense	distal	-6	no	8.102	7.981	EPSD	ICGC;COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	Q9Y2I7	PIKFYVE	P31749	AKT1	S501	D508Y	508	Missense	distal	7	no	8.102	8.136	EPSD	ICGC	7.780	Up-regulation
AGC_Akt_AKT1_ST	Q9Y2I7	PIKFYVE	P31749	AKT1	S845	A850S	850	Missense	distal	5	no	13.120	13.171	EPSD	ICGC;COSMIC	7.780	Up-regulation
AGC_Akt_AKT1_ST	Q9Y2I7	PIKFYVE	P31749	AKT1	S1042	S1042C	1042	Missense	central	0	yes	9.279	0.000	EPSD	ICGC;COSMIC	7.780	Loss
AGC_Akt_AKT1_ST	Q9Y2I7	PIKFYVE	P31749	AKT1	S1042	K1046N	1046	Missense	distal	4	no	9.279	9.411	EPSD	ICGC;COSMIC	7.780	Up-regulation
AGC_Akt_AKT1_ST	Q9Y2I7	PIKFYVE	P31749	AKT1	S1042	Q1047R	1047	Missense	distal	5	no	9.279	9.330	EPSD	ICGC;COSMIC	7.780	Up-regulation
AGC_Akt_AKT1_ST	Q9Y2I7	PIKFYVE	P31749	AKT1	S1111	Q1105H	1105	Missense	distal	-6	no	9.608	9.573	EPSD	ICGC	7.780	Down-regulation
AGC_Akt_AKT1_ST	Q9Y2I7	PIKFYVE	P31749	AKT1	S1111	L1107I	1107	Missense	distal	-4	no	9.608	9.350	EPSD	ICGC	7.780	Down-regulation
AGC_Akt_AKT1_ST	Q9Y2I7	PIKFYVE	P31749	AKT1	S1440	E1445G	1445	Missense	distal	5	no	7.968	7.937	EPSD	ICGC;COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	Q9Y2I7	PIKFYVE	P31749	AKT1	S1522	K1516N	1516	Missense	distal	-6	no	8.574	8.507	EPSD	ICGC;COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	Q9Y2I7	PIKFYVE	P31749	AKT1	S1522	P1524S	1524	Missense	proximal	2	no	8.574	8.910	EPSD	ICGC;GDSC;CCLE	7.780	Up-regulation
AGC_Akt_AKT1_ST	Q9Y2I7	PIKFYVE	P31749	AKT1	S1522	R1529I	1529	Missense	distal	7	no	8.574	8.469	EPSD	ICGC	7.780	Down-regulation
AGC_Akt_AKT1_ST	Q9Y2I7	PIKFYVE	P31749	AKT1	S1722	R1728H	1728	Missense	distal	6	no	8.985	8.866	EPSD	ICGC;COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	Q9Y4P1	ATG4B	P31749	AKT1	S34	R31K	31	Missense	distal	-3	no	11.739	7.218	PhosphoSitePlus	ICGC;COSMIC	7.780	Loss
AGC_Akt_AKT1_ST	Q9Y4P1	ATG4B	P31749	AKT1	S34	S34I	34	Missense	central	0	yes	11.739	0.000	PhosphoSitePlus	ICGC;COSMIC	7.780	Loss
AGC_Akt_AKT1_ST	Q6R327	RICTOR	P31749	AKT1	S21	N19S	19	Missense	proximal	-2	no	15.434	16.120	EPSD	ICGC;COSMIC	7.780	Up-regulation
AGC_Akt_AKT1_ST	Q6R327	RICTOR	P31749	AKT1	S35	N37K	37	Missense	proximal	2	no	10.036	10.321	EPSD	ICGC	7.780	Up-regulation
AGC_Akt_AKT1_ST	Q6R327	RICTOR	P31749	AKT1	S383	R380C	380	Missense	distal	-3	no	13.047	6.873	EPSD	ICGC;COSMIC	7.780	Loss
AGC_Akt_AKT1_ST	Q6R327	RICTOR	P31749	AKT1	S383	P385T	385	Missense	proximal	2	no	13.047	13.308	EPSD	ICGC	7.780	Up-regulation
AGC_Akt_AKT1_ST	Q6R327	RICTOR	P31749	AKT1	S383	L377F	377	Missense	distal	-6	no	13.047	13.023	EPSD	ICGC	7.780	Down-regulation
AGC_Akt_AKT1_ST	Q6R327	RICTOR	P31749	AKT1	S383	A381V	381	Missense	proximal	-2	no	13.047	12.308	EPSD	ICGC	7.780	Down-regulation
AGC_Akt_AKT1_ST	Q6R327	RICTOR	P31749	AKT1	S703	L700R	700	Missense	distal	-3	no	5.278	12.272	EPSD	ICGC;COSMIC	7.780	Gain
AGC_Akt_AKT1_ST	Q6R327	RICTOR	P31749	AKT1	S810	L809F	809	Missense	proximal	-1	no	9.152	9.146	EPSD	ICGC;COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	Q6R327	RICTOR	P31749	AKT1	S1035	S1031C	1031	Missense	distal	-4	no	11.352	9.759	EPSD	ICGC;COSMIC;GDSC;CCLE	7.780	Down-regulation
AGC_Akt_AKT1_ST	Q6R327	RICTOR	P31749	AKT1	S1037	S1031C	1031	Missense	distal	-6	no	9.015	8.869	EPSD	ICGC;COSMIC;GDSC;CCLE	7.780	Down-regulation
AGC_Akt_AKT1_ST	Q6R327	RICTOR	P31749	AKT1	T1198	V1204I	1204	Missense	distal	6	no	8.944	8.894	EPSD	ICGC;COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	Q6R327	RICTOR	P31749	AKT1	S1219	R1216C	1216	Missense	distal	-3	no	11.267	5.093	EPSD	ICGC;COSMIC	7.780	Loss
AGC_Akt_AKT1_ST	Q6R327	RICTOR	P31749	AKT1	S1302	L1296P	1296	Missense	distal	-6	no	13.316	13.303	EPSD	ICGC;COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	P45985	MAP2K4	P31749	AKT1	S292	G294E	294	Missense	proximal	2	no	9.191	9.335	EPSD	ICGC;COSMIC	7.780	Up-regulation
AGC_Akt_AKT1_ST	Q96CG3	TIFA	P31749	AKT1	S174	M179I	179	Missense	distal	5	no	8.143	8.103	EPSD	ICGC	7.780	Down-regulation
AGC_Akt_AKT1_ST	Q96CG3	TIFA	P31749	AKT1	S174	L168I	168	Missense	distal	-6	no	8.143	8.073	EPSD	ICGC;COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	Q96CG3	TIFA	P31749	AKT1	S174	P176Q	176	Missense	proximal	2	no	8.143	8.189	EPSD	ICGC;COSMIC	7.780	Up-regulation
AGC_Akt_AKT1_ST	Q96CG3	TIFA	P31749	AKT1	S175	M179I	179	Missense	distal	4	no	7.812	7.910	EPSD	ICGC	7.780	Up-regulation
AGC_Akt_AKT1_ST	Q96CG3	TIFA	P31749	AKT1	S175	L168I	168	Missense	distal	-7	no	7.812	7.674	EPSD	ICGC;COSMIC	7.780	Loss
AGC_Akt_AKT1_ST	Q96CG3	TIFA	P31749	AKT1	S175	P176Q	176	Missense	proximal	1	no	7.812	7.817	EPSD	ICGC;COSMIC	7.780	Up-regulation
AGC_Akt_AKT1_ST	Q8WX93	PALLD	P31749	AKT1	S13	S13N	13	Missense	central	0	yes	8.762	0.000	EPSD	ICGC	7.780	Loss
AGC_Akt_AKT1_ST	Q8WX93	PALLD	P31749	AKT1	S13	M17I	17	Missense	distal	4	no	8.762	8.860	EPSD	ICGC	7.780	Up-regulation
AGC_Akt_AKT1_ST	Q8WX93	PALLD	P31749	AKT1	S13	S9N	9	Missense	distal	-4	no	8.762	8.195	EPSD	ICGC	7.780	Down-regulation
AGC_Akt_AKT1_ST	Q8WX93	PALLD	P31749	AKT1	S125	A123S	123	Missense	proximal	-2	no	8.726	9.178	EPSD	ICGC	7.780	Up-regulation
AGC_Akt_AKT1_ST	Q8WX93	PALLD	P31749	AKT1	S356	A357T	357	Missense	proximal	1	no	7.847	8.114	EPSD	ICGC	7.780	Up-regulation
AGC_Akt_AKT1_ST	Q7Z6J0	SH3RF1	P31749	AKT1	S58	L63I	63	Missense	distal	5	no	8.450	8.420	EPSD	ICGC	7.780	Down-regulation
AGC_Akt_AKT1_ST	Q7Z6J0	SH3RF1	P31749	AKT1	S58	S65I	65	Missense	distal	7	no	8.450	8.353	EPSD	ICGC;COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	Q7Z6J0	SH3RF1	P31749	AKT1	S125	P129Q	129	Missense	distal	4	no	10.727	10.705	EPSD	ICGC;COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	Q7Z6J0	SH3RF1	P31749	AKT1	S125	P121T	121	Missense	distal	-4	no	10.727	11.519	EPSD	ICGC	7.780	Up-regulation
AGC_Akt_AKT1_ST	Q7Z6J0	SH3RF1	P31749	AKT1	S125	V130L	130	Missense	distal	5	no	10.727	10.720	EPSD	ICGC;COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	Q7Z6J0	SH3RF1	P31749	AKT1	S125	G132V	132	Missense	distal	7	no	10.727	10.745	EPSD	ICGC;COSMIC	7.780	Up-regulation
AGC_Akt_AKT1_ST	Q7Z6J0	SH3RF1	P31749	AKT1	T306	N312K	312	Missense	distal	6	no	8.492	8.570	EPSD	ICGC	7.780	Up-regulation
AGC_Akt_AKT1_ST	Q7Z6J0	SH3RF1	P31749	AKT1	S315	N312K	312	Missense	distal	-3	no	5.329	8.285	EPSD	ICGC	7.780	Gain
AGC_Akt_AKT1_ST	Q7Z6J0	SH3RF1	P31749	AKT1	T509	V508G	508	Missense	proximal	-1	no	10.462	10.467	EPSD	ICGC;COSMIC;GDSC	7.780	Up-regulation
AGC_Akt_AKT1_ST	Q7Z6J0	SH3RF1	P31749	AKT1	T529	S534F	534	Missense	distal	5	no	11.455	11.382	EPSD	ICGC;COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	Q7Z6J0	SH3RF1	P31749	AKT1	T684	P687A	687	Missense	distal	3	no	9.469	9.493	EPSD	ICGC	7.780	Up-regulation
AGC_Akt_AKT1_ST	Q7Z6J0	SH3RF1	P31749	AKT1	S735	P737L	737	Missense	proximal	2	no	10.577	10.368	EPSD	ICGC	7.780	Down-regulation
AGC_Akt_AKT1_ST	Q7Z6J0	SH3RF1	P31749	AKT1	S772	S772A	772	Missense	central	0	yes	12.049	0.000	EPSD	ICGC	7.780	Loss
AGC_Akt_AKT1_ST	Q7Z6J0	SH3RF1	P31749	AKT1	S772	G771S	771	Missense	proximal	-1	no	12.049	12.078	EPSD	ICGC;COSMIC	7.780	Up-regulation
AGC_Akt_AKT1_ST	Q8NCD3	HJURP	P31749	AKT1	S201	G203C	203	Missense	proximal	2	no	8.190	7.697	EPSD	ICGC;COSMIC	7.780	Loss
AGC_Akt_AKT1_ST	Q8NCD3	HJURP	P31749	AKT1	S201	I197V	197	Missense	distal	-4	no	8.190	8.478	EPSD	ICGC;COSMIC	7.780	Up-regulation
AGC_Akt_AKT1_ST	Q8NCD3	HJURP	P31749	AKT1	S276	P279S	279	Missense	distal	3	no	11.646	11.728	EPSD	ICGC	7.780	Up-regulation
AGC_Akt_AKT1_ST	Q8NCD3	HJURP	P31749	AKT1	S281	P279S	279	Missense	proximal	-2	no	7.157	7.981	EPSD	ICGC	7.780	Gain
AGC_Akt_AKT1_ST	Q8NCD3	HJURP	P31749	AKT1	S473	P471T	471	Missense	proximal	-2	no	7.071	7.829	EPSD	ICGC	7.780	Gain
AGC_Akt_AKT1_ST	P35568	IRS1	P31749	AKT1	S36	E37Q	37	Missense	proximal	1	no	9.585	9.531	EPSD	ICGC;COSMIC;CCLE	7.780	Down-regulation
AGC_Akt_AKT1_ST	P35568	IRS1	P31749	AKT1	S189	R184H	184	Missense	distal	-5	no	9.152	6.057	EPSD	ICGC	7.780	Loss
AGC_Akt_AKT1_ST	P35568	IRS1	P31749	AKT1	S268	R265H	265	Missense	distal	-3	no	11.282	6.583	EPSD	ICGC	7.780	Loss
AGC_Akt_AKT1_ST	P35568	IRS1	P31749	AKT1	S268	F264L	264	Missense	distal	-4	no	11.282	11.326	EPSD	ICGC	7.780	Up-regulation
AGC_Akt_AKT1_ST	P35568	IRS1	P31749	AKT1	S268	S272P	272	Missense	distal	4	no	11.282	11.437	EPSD	ICGC	7.780	Up-regulation
AGC_Akt_AKT1_ST	P35568	IRS1	P31749	AKT1	S268	S268I	268	Missense	central	0	yes	11.282	0.000	EPSD	ICGC;COSMIC	7.780	Loss
AGC_Akt_AKT1_ST	P35568	IRS1	P31749	AKT1	S270	R265H	265	Missense	distal	-5	no	14.918	11.823	EPSD	ICGC	7.780	Down-regulation
AGC_Akt_AKT1_ST	P35568	IRS1	P31749	AKT1	S270	F264L	264	Missense	distal	-6	no	14.918	14.942	EPSD	ICGC	7.780	Up-regulation
AGC_Akt_AKT1_ST	P35568	IRS1	P31749	AKT1	S270	S272P	272	Missense	proximal	2	no	14.918	14.582	EPSD	ICGC	7.780	Down-regulation
AGC_Akt_AKT1_ST	P35568	IRS1	P31749	AKT1	S270	S268I	268	Missense	proximal	-2	no	14.918	13.677	EPSD	ICGC;COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	P35568	IRS1	P31749	AKT1	S272	R265H	265	Missense	distal	-7	no	12.914	12.613	EPSD	ICGC	7.780	Down-regulation
AGC_Akt_AKT1_ST	P35568	IRS1	P31749	AKT1	S272	S272P	272	Missense	central	0	yes	12.914	0.000	EPSD	ICGC	7.780	Loss
AGC_Akt_AKT1_ST	P35568	IRS1	P31749	AKT1	S272	N278T	278	Missense	distal	6	no	12.914	13.003	EPSD	ICGC	7.780	Up-regulation
AGC_Akt_AKT1_ST	P35568	IRS1	P31749	AKT1	S272	S268I	268	Missense	distal	-4	no	12.914	11.533	EPSD	ICGC;COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	P35568	IRS1	P31749	AKT1	T305	T300P	300	Missense	distal	-5	no	13.125	12.845	EPSD	ICGC;COSMIC;GDSC	7.780	Down-regulation
AGC_Akt_AKT1_ST	P35568	IRS1	P31749	AKT1	S307	T300P	300	Missense	distal	-7	no	16.317	16.072	EPSD	ICGC;COSMIC;GDSC	7.780	Down-regulation
AGC_Akt_AKT1_ST	P35568	IRS1	P31749	AKT1	S330	G332S	332	Missense	proximal	2	no	14.092	14.424	EPSD	ICGC;COSMIC	7.780	Up-regulation
AGC_Akt_AKT1_ST	P35568	IRS1	P31749	AKT1	S341	S345N	345	Missense	distal	4	no	10.756	10.865	EPSD	ICGC	7.780	Up-regulation
AGC_Akt_AKT1_ST	P35568	IRS1	P31749	AKT1	S362	H355Q	355	Missense	distal	-7	no	8.382	8.489	EPSD	ICGC	7.780	Up-regulation
AGC_Akt_AKT1_ST	P35568	IRS1	P31749	AKT1	S362	L369H	369	Missense	distal	7	no	8.382	8.384	EPSD	ICGC;COSMIC	7.780	Up-regulation
AGC_Akt_AKT1_ST	P35568	IRS1	P31749	AKT1	S413	S412P	412	Missense	proximal	-1	no	12.105	12.076	EPSD	ICGC	7.780	Down-regulation
AGC_Akt_AKT1_ST	P35568	IRS1	P31749	AKT1	S413	A414D	414	Missense	proximal	1	no	12.105	11.965	EPSD	ICGC	7.780	Down-regulation
AGC_Akt_AKT1_ST	P35568	IRS1	P31749	AKT1	S413	R411L	411	Missense	proximal	-2	no	12.105	11.436	EPSD	ICGC;COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	P35568	IRS1	P31749	AKT1	S413	R410W	410	Missense	distal	-3	no	12.105	3.164	EPSD	ICGC	7.780	Loss
AGC_Akt_AKT1_ST	P35568	IRS1	P31749	AKT1	S415	S412P	412	Missense	distal	-3	no	8.256	9.392	EPSD	ICGC	7.780	Up-regulation
AGC_Akt_AKT1_ST	P35568	IRS1	P31749	AKT1	S415	S421R	421	Missense	distal	6	no	8.256	8.254	EPSD	ICGC	7.780	Down-regulation
AGC_Akt_AKT1_ST	P35568	IRS1	P31749	AKT1	S415	A414D	414	Missense	proximal	-1	no	8.256	8.228	EPSD	ICGC	7.780	Down-regulation
AGC_Akt_AKT1_ST	P35568	IRS1	P31749	AKT1	S415	R411L	411	Missense	distal	-4	no	8.256	7.046	EPSD	ICGC;COSMIC	7.780	Loss
AGC_Akt_AKT1_ST	P35568	IRS1	P31749	AKT1	S415	R410W	410	Missense	distal	-5	no	8.256	2.736	EPSD	ICGC	7.780	Loss
AGC_Akt_AKT1_ST	P35568	IRS1	P31749	AKT1	S444	D437Y	437	Missense	distal	-7	no	7.937	8.103	EPSD	ICGC;COSMIC	7.780	Up-regulation
AGC_Akt_AKT1_ST	P35568	IRS1	P31749	AKT1	T525	S531Y	531	Missense	distal	6	no	14.903	14.815	EPSD	ICGC	7.780	Down-regulation
AGC_Akt_AKT1_ST	P35568	IRS1	P31749	AKT1	S527	S531Y	531	Missense	distal	4	no	16.468	16.604	EPSD	ICGC	7.780	Up-regulation
AGC_Akt_AKT1_ST	P35568	IRS1	P31749	AKT1	S574	R572M	572	Missense	proximal	-2	no	7.811	7.160	EPSD	ICGC;COSMIC	7.780	Loss
AGC_Akt_AKT1_ST	P35568	IRS1	P31749	AKT1	S574	P578H	578	Missense	distal	4	no	7.811	7.851	EPSD	ICGC	7.780	Up-regulation
AGC_Akt_AKT1_ST	P35568	IRS1	P31749	AKT1	S574	H571N	571	Missense	distal	-3	no	7.811	5.033	EPSD	ICGC	7.780	Loss
AGC_Akt_AKT1_ST	P35568	IRS1	P31749	AKT1	S574	A575T	575	Missense	proximal	1	no	7.811	8.078	EPSD	ICGC;COSMIC	7.780	Up-regulation
AGC_Akt_AKT1_ST	P35568	IRS1	P31749	AKT1	S603	R600H	600	Missense	distal	-3	no	12.032	7.333	EPSD	ICGC;COSMIC	7.780	Loss
AGC_Akt_AKT1_ST	P35568	IRS1	P31749	AKT1	T605	R600H	600	Missense	distal	-5	no	9.252	6.157	EPSD	ICGC;COSMIC	7.780	Loss
AGC_Akt_AKT1_ST	P35568	IRS1	P31749	AKT1	S629	P634S	634	Missense	distal	5	no	11.601	11.654	PhosphoSitePlus	ICGC;COSMIC	7.780	Up-regulation
AGC_Akt_AKT1_ST	P35568	IRS1	P31749	AKT1	S629	Y632C	632	Missense	distal	3	no	11.601	11.493	PhosphoSitePlus	ICGC;COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	P35568	IRS1	P31749	AKT1	S629	K627N	627	Missense	proximal	-2	no	11.601	10.665	PhosphoSitePlus	ICGC;COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	P35568	IRS1	P31749	AKT1	T793	T793A	793	Missense	central	0	yes	10.368	0.000	EPSD	ICGC;COSMIC	7.780	Loss
AGC_Akt_AKT1_ST	P35568	IRS1	P31749	AKT1	T793	Y800C	800	Missense	distal	7	no	10.368	10.288	EPSD	ICGC;COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	P35568	IRS1	P31749	AKT1	T793	R790H	790	Missense	distal	-3	no	10.368	5.669	EPSD	ICGC	7.780	Loss
AGC_Akt_AKT1_ST	P35568	IRS1	P31749	AKT1	T859	P866T	866	Missense	distal	7	no	8.975	9.044	EPSD	ICGC	7.780	Up-regulation
AGC_Akt_AKT1_ST	P35568	IRS1	P31749	AKT1	S862	K867T	867	Missense	distal	5	no	8.757	8.756	EPSD	ICGC	7.780	Down-regulation
AGC_Akt_AKT1_ST	P35568	IRS1	P31749	AKT1	S862	P866T	866	Missense	distal	4	no	8.757	8.596	EPSD	ICGC	7.780	Down-regulation
AGC_Akt_AKT1_ST	P35568	IRS1	P31749	AKT1	S974	G971R	971	Missense	distal	-3	no	3.780	10.536	EPSD	ICGC;COSMIC	7.780	Gain
AGC_Akt_AKT1_ST	P35568	IRS1	P31749	AKT1	S1100	S1106L	1106	Missense	distal	6	no	13.515	13.411	EPSD	ICGC;COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	P35568	IRS1	P31749	AKT1	S1101	S1106L	1106	Missense	distal	5	no	16.825	16.759	EPSD	ICGC;COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	P35568	IRS1	P31749	AKT1	T1103	S1106L	1106	Missense	distal	3	no	7.892	7.794	EPSD	ICGC;COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	P35568	IRS1	P31749	AKT1	S1142	D1137N	1137	Missense	distal	-5	no	8.598	8.160	EPSD	ICGC	7.780	Down-regulation
AGC_Akt_AKT1_ST	P35568	IRS1	P31749	AKT1	S1143	D1137N	1137	Missense	distal	-6	no	12.388	12.459	EPSD	ICGC	7.780	Up-regulation
AGC_Akt_AKT1_ST	P35568	IRS1	P31749	AKT1	S1216	L1211R	1211	Missense	distal	-5	no	5.399	9.525	EPSD	ICGC;COSMIC	7.780	Gain
AGC_Akt_AKT1_ST	P35568	IRS1	P31749	AKT1	S1223	R1220H	1220	Missense	distal	-3	no	13.710	9.011	EPSD	ICGC;COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	P35568	IRS1	P31749	AKT1	S1223	T1219P	1219	Missense	distal	-4	no	13.710	12.918	EPSD	ICGC;COSMIC;GDSC	7.780	Down-regulation
AGC_Akt_AKT1_ST	P35568	IRS1	P31749	AKT1	S1231	Q1235H	1235	Missense	distal	4	no	8.367	8.428	EPSD	ICGC;COSMIC	7.780	Up-regulation
AGC_Akt_AKT1_ST	Q16875	PFKFB3	P31749	AKT1	S211	D209Y	209	Missense	proximal	-2	no	9.597	10.068	EPSD	ICGC	7.780	Up-regulation
AGC_Akt_AKT1_ST	Q16875	PFKFB3	P31749	AKT1	S280	A281T	281	Missense	proximal	1	no	8.046	8.312	EPSD	ICGC	7.780	Up-regulation
AGC_Akt_AKT1_ST	Q16875	PFKFB3	P31749	AKT1	S280	R274W	274	Missense	distal	-6	no	8.046	7.898	EPSD	ICGC;COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	Q16875	PFKFB3	P31749	AKT1	T359	R356H	356	Missense	distal	-3	no	9.224	4.525	EPSD	ICGC;COSMIC	7.780	Loss
AGC_Akt_AKT1_ST	Q16875	PFKFB3	P31749	AKT1	S446	R443L	443	Missense	distal	-3	no	10.569	3.575	EPSD	ICGC;COSMIC	7.780	Loss
AGC_Akt_AKT1_ST	Q15118	PDK1	P31749	AKT1	S25	S29R	29	Missense	distal	4	no	10.753	10.764	EPSD	ICGC;COSMIC	7.780	Up-regulation
AGC_Akt_AKT1_ST	Q15118	PDK1	P31749	AKT1	S25	S30L	30	Missense	distal	5	no	10.753	10.686	EPSD	ICGC	7.780	Down-regulation
AGC_Akt_AKT1_ST	Q15118	PDK1	P31749	AKT1	S25	S30P	30	Missense	distal	5	no	10.753	10.700	EPSD	ICGC	7.780	Down-regulation
AGC_Akt_AKT1_ST	Q15118	PDK1	P31749	AKT1	T346	P351L	351	Missense	distal	5	no	14.110	14.096	PhosphoSitePlus	ICGC;COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	Q15118	PDK1	P31749	AKT1	T346	R343L	343	Missense	distal	-3	no	14.110	7.116	PhosphoSitePlus	ICGC	7.780	Loss
AGC_Akt_AKT1_ST	Q15118	PDK1	P31749	AKT1	T346	A353S	353	Missense	distal	7	no	14.110	14.161	PhosphoSitePlus	ICGC	7.780	Up-regulation
AGC_Akt_AKT1_ST	P29317	EPHA2	P31749	AKT1	S433	S433N	433	Missense	central	0	yes	10.266	0.000	EPSD	ICGC	7.780	Loss
AGC_Akt_AKT1_ST	P29317	EPHA2	P31749	AKT1	S433	S426R	426	Missense	distal	-7	no	10.266	10.322	EPSD	ICGC;COSMIC	7.780	Up-regulation
AGC_Akt_AKT1_ST	P29317	EPHA2	P31749	AKT1	S433	A430D	430	Missense	distal	-3	no	10.266	10.619	EPSD	ICGC	7.780	Up-regulation
AGC_Akt_AKT1_ST	P29317	EPHA2	P31749	AKT1	S897	R894Q	894	Missense	distal	-3	no	10.610	3.399	PhosphoSitePlus	ICGC;COSMIC	7.780	Loss
AGC_Akt_AKT1_ST	P29317	EPHA2	P31749	AKT1	S899	R894Q	894	Missense	distal	-5	no	9.398	5.171	EPSD	ICGC;COSMIC	7.780	Loss
AGC_Akt_AKT1_ST	P29317	EPHA2	P31749	AKT1	S899	P905S	905	Missense	distal	6	no	9.398	9.492	EPSD	ICGC	7.780	Up-regulation
AGC_Akt_AKT1_ST	P29317	EPHA2	P31749	AKT1	S910	R907C	907	Missense	distal	-3	no	11.195	5.022	EPSD	ICGC;GDSC	7.780	Loss
AGC_Akt_AKT1_ST	P29317	EPHA2	P31749	AKT1	S910	W912C	912	Missense	proximal	2	no	11.195	10.998	EPSD	ICGC;COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	P29317	EPHA2	P31749	AKT1	S910	P905S	905	Missense	distal	-5	no	11.195	10.735	EPSD	ICGC	7.780	Down-regulation
AGC_Akt_AKT1_ST	P29317	EPHA2	P31749	AKT1	S961	H954N	954	Missense	distal	-7	no	10.019	10.150	EPSD	ICGC	7.780	Up-regulation
AGC_Akt_AKT1_ST	P29317	EPHA2	P31749	AKT1	S961	R957C	957	Missense	distal	-4	no	10.019	8.340	EPSD	ICGC;COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	O15519	CFLAR	P31749	AKT1	S273	S273F	273	Missense	central	0	yes	8.098	0.000	PhosphoSitePlus	ICGC;COSMIC	7.780	Loss
AGC_Akt_AKT1_ST	O15519	CFLAR	P31749	AKT1	S273	G275C	275	Missense	proximal	2	no	8.098	7.606	PhosphoSitePlus	ICGC	7.780	Loss
AGC_Akt_AKT1_ST	P26358	DNMT1	P31749	AKT1	T12	P16T	16	Missense	distal	4	no	11.540	11.379	EPSD	ICGC;COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	P26358	DNMT1	P31749	AKT1	T12	I18M	18	Missense	distal	6	no	11.540	11.606	EPSD	ICGC	7.780	Up-regulation
AGC_Akt_AKT1_ST	P26358	DNMT1	P31749	AKT1	S141	P138L	138	Missense	distal	-3	no	10.414	10.060	EPSD	ICGC;COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	P26358	DNMT1	P31749	AKT1	S141	P135T	135	Missense	distal	-6	no	10.414	10.509	EPSD	ICGC	7.780	Up-regulation
AGC_Akt_AKT1_ST	P26358	DNMT1	P31749	AKT1	S141	R139K	139	Missense	proximal	-2	no	10.414	10.853	EPSD	ICGC;COSMIC	7.780	Up-regulation
AGC_Akt_AKT1_ST	P26358	DNMT1	P31749	AKT1	S141	R139S	139	Missense	proximal	-2	no	10.414	10.602	EPSD	ICGC;COSMIC	7.780	Up-regulation
AGC_Akt_AKT1_ST	P26358	DNMT1	P31749	AKT1	S141	A147T	147	Missense	distal	6	no	10.414	10.517	EPSD	ICGC	7.780	Up-regulation
AGC_Akt_AKT1_ST	P26358	DNMT1	P31749	AKT1	S141	R136H	136	Missense	distal	-5	no	10.414	7.319	EPSD	ICGC;COSMIC	7.780	Loss
AGC_Akt_AKT1_ST	P26358	DNMT1	P31749	AKT1	S143	P138L	138	Missense	distal	-5	no	11.970	11.854	PhosphoSitePlus	ICGC;COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	P26358	DNMT1	P31749	AKT1	S143	R139K	139	Missense	distal	-4	no	11.970	11.956	PhosphoSitePlus	ICGC;COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	P26358	DNMT1	P31749	AKT1	S143	R139S	139	Missense	distal	-4	no	11.970	11.884	PhosphoSitePlus	ICGC;COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	P26358	DNMT1	P31749	AKT1	S143	A147T	147	Missense	distal	4	no	11.970	11.841	PhosphoSitePlus	ICGC	7.780	Down-regulation
AGC_Akt_AKT1_ST	P26358	DNMT1	P31749	AKT1	S143	R136H	136	Missense	distal	-7	no	11.970	11.668	PhosphoSitePlus	ICGC;COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	P26358	DNMT1	P31749	AKT1	T229	E236Q	236	Missense	distal	7	no	9.854	9.839	EPSD	ICGC;COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	P78362	SRPK2	P31749	AKT1	S9	P14L	14	Missense	distal	5	no	9.684	9.671	EPSD	ICGC	7.780	Down-regulation
AGC_Akt_AKT1_ST	P78362	SRPK2	P31749	AKT1	S9	E6D	6	Missense	distal	-3	no	9.684	10.305	EPSD	ICGC;COSMIC	7.780	Up-regulation
AGC_Akt_AKT1_ST	P78362	SRPK2	P31749	AKT1	S10	P14L	14	Missense	distal	4	no	10.902	10.935	EPSD	ICGC	7.780	Up-regulation
AGC_Akt_AKT1_ST	P78362	SRPK2	P31749	AKT1	S10	E6D	6	Missense	distal	-4	no	10.902	10.126	EPSD	ICGC;COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	P78362	SRPK2	P31749	AKT1	S11	P14L	14	Missense	distal	3	no	7.864	7.848	EPSD	ICGC	7.780	Down-regulation
AGC_Akt_AKT1_ST	P78362	SRPK2	P31749	AKT1	S11	Q18K	18	Missense	distal	7	no	7.864	7.912	EPSD	ICGC	7.780	Up-regulation
AGC_Akt_AKT1_ST	P78362	SRPK2	P31749	AKT1	S11	E6D	6	Missense	distal	-5	no	7.864	7.913	EPSD	ICGC;COSMIC	7.780	Up-regulation
AGC_Akt_AKT1_ST	P78362	SRPK2	P31749	AKT1	S483	Q480K	480	Missense	distal	-3	no	5.770	8.461	EPSD	ICGC	7.780	Gain
AGC_Akt_AKT1_ST	P78362	SRPK2	P31749	AKT1	T492	D488Y	488	Missense	distal	-4	no	11.906	12.335	PhosphoSitePlus	ICGC;COSMIC	7.780	Up-regulation
AGC_Akt_AKT1_ST	P78362	SRPK2	P31749	AKT1	T492	V493L	493	Missense	proximal	1	no	11.906	12.006	PhosphoSitePlus	ICGC;COSMIC	7.780	Up-regulation
AGC_Akt_AKT1_ST	P78362	SRPK2	P31749	AKT1	S494	D500N	500	Missense	distal	6	no	16.808	16.889	EPSD	ICGC;COSMIC	7.780	Up-regulation
AGC_Akt_AKT1_ST	P78362	SRPK2	P31749	AKT1	S494	D488Y	488	Missense	distal	-6	no	16.808	16.867	EPSD	ICGC;COSMIC	7.780	Up-regulation
AGC_Akt_AKT1_ST	P78362	SRPK2	P31749	AKT1	S494	V493L	493	Missense	proximal	-1	no	16.808	16.814	EPSD	ICGC;COSMIC	7.780	Up-regulation
AGC_Akt_AKT1_ST	P78362	SRPK2	P31749	AKT1	S494	D500Y	500	Missense	distal	6	no	16.808	16.869	EPSD	ICGC;COSMIC	7.780	Up-regulation
AGC_Akt_AKT1_ST	P78362	SRPK2	P31749	AKT1	S496	P502T	502	Missense	distal	6	no	10.250	10.364	EPSD	ICGC	7.780	Up-regulation
AGC_Akt_AKT1_ST	P78362	SRPK2	P31749	AKT1	S496	D500N	500	Missense	distal	4	no	10.250	10.135	EPSD	ICGC;COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	P78362	SRPK2	P31749	AKT1	S496	V493L	493	Missense	distal	-3	no	10.250	10.121	EPSD	ICGC;COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	P78362	SRPK2	P31749	AKT1	S496	D500Y	500	Missense	distal	4	no	10.250	10.161	EPSD	ICGC;COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	P78362	SRPK2	P31749	AKT1	S616	H612N	612	Missense	distal	-4	no	10.889	11.295	EPSD	ICGC	7.780	Up-regulation
AGC_Akt_AKT1_ST	Q96KG9	SCYL1	P31749	AKT1	S41	V47F	47	Missense	distal	6	no	8.542	8.536	EPSD	ICGC	7.780	Down-regulation
AGC_Akt_AKT1_ST	Q96KG9	SCYL1	P31749	AKT1	T469	S470Y	470	Missense	proximal	1	no	13.647	13.640	PhosphoSitePlus	ICGC;COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	Q96KG9	SCYL1	P31749	AKT1	T469	T476P	476	Missense	distal	7	no	13.647	13.578	PhosphoSitePlus	ICGC;COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	Q96KG9	SCYL1	P31749	AKT1	S723	R720W	720	Missense	distal	-3	no	12.444	3.503	EPSD	ICGC;COSMIC	7.780	Loss
AGC_Akt_AKT1_ST	P15976	GATA1	P31749	AKT1	T256	R253L	253	Missense	distal	-3	no	10.228	3.234	EPSD	ICGC	7.780	Loss
AGC_Akt_AKT1_ST	P15976	GATA1	P31749	AKT1	S310	Q303K	303	Missense	distal	-7	no	17.117	17.298	PhosphoSitePlus	ICGC;COSMIC	7.780	Up-regulation
AGC_Akt_AKT1_ST	P15976	GATA1	P31749	AKT1	S310	R307S	307	Missense	distal	-3	no	17.117	9.340	PhosphoSitePlus	ICGC;COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	P15976	GATA1	P31749	AKT1	S319	G325R	325	Missense	distal	6	no	10.053	10.157	EPSD	ICGC;COSMIC	7.780	Up-regulation
AGC_Akt_AKT1_ST	P15976	GATA1	P31749	AKT1	S320	G325R	325	Missense	distal	5	no	13.443	13.513	EPSD	ICGC;COSMIC	7.780	Up-regulation
AGC_Akt_AKT1_ST	Q99418	CYTH2	P31749	AKT1	T276	R280H	280	Missense	distal	4	no	11.605	11.790	PhosphoSitePlus	ICGC;COSMIC	7.780	Up-regulation
AGC_Akt_AKT1_ST	Q99418	CYTH2	P31749	AKT1	S392	R387T	387	Missense	distal	-5	no	15.149	11.419	EPSD	ICGC;COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	Q99418	CYTH2	P31749	AKT1	S392	R390W	390	Missense	proximal	-2	no	15.149	13.894	EPSD	ICGC;COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	Q99418	CYTH2	P31749	AKT1	S392	A386V	386	Missense	distal	-6	no	15.149	15.128	EPSD	ICGC;COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	P17542	TAL1	P31749	AKT1	S7	E3K	3	Missense	distal	-4	no	12.747	13.331	EPSD	ICGC	7.780	Up-regulation
AGC_Akt_AKT1_ST	P17542	TAL1	P31749	AKT1	S7	T2A	2	Missense	distal	-5	no	12.747	12.622	EPSD	ICGC	7.780	Down-regulation
AGC_Akt_AKT1_ST	P17542	TAL1	P31749	AKT1	S7	P5S	5	Missense	proximal	-2	no	12.747	13.571	EPSD	ICGC;COSMIC	7.780	Up-regulation
AGC_Akt_AKT1_ST	P17542	TAL1	P31749	AKT1	S122	A125T	125	Missense	distal	3	no	7.959	8.016	EPSD	ICGC	7.780	Up-regulation
AGC_Akt_AKT1_ST	P17542	TAL1	P31749	AKT1	S172	P173L	173	Missense	proximal	1	no	11.400	11.654	EPSD	ICGC	7.780	Up-regulation
AGC_Akt_AKT1_ST	P17542	TAL1	P31749	AKT1	S224	R230C	230	Missense	distal	6	no	8.208	8.007	EPSD	ICGC;COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	P17542	TAL1	P31749	AKT1	T256	T256I	256	Missense	central	0	yes	11.600	0.000	EPSD	ICGC;COSMIC	7.780	Loss
AGC_Akt_AKT1_ST	P17542	TAL1	P31749	AKT1	T256	E249K	249	Missense	distal	-7	no	11.600	11.792	EPSD	ICGC	7.780	Up-regulation
AGC_Akt_AKT1_ST	P17542	TAL1	P31749	AKT1	T256	G250C	250	Missense	distal	-6	no	11.600	11.533	EPSD	ICGC;COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	P17542	TAL1	P31749	AKT1	T313	P310H	310	Missense	distal	-3	no	6.441	8.382	EPSD	ICGC	7.780	Gain
AGC_Akt_AKT1_ST	P17542	TAL1	P31749	AKT1	S316	P310H	310	Missense	distal	-6	no	8.110	8.089	EPSD	ICGC	7.780	Down-regulation
AGC_Akt_AKT1_ST	P17542	TAL1	P31749	AKT1	S316	P310T	310	Missense	distal	-6	no	8.110	8.205	EPSD	ICGC	7.780	Up-regulation
AGC_Akt_AKT1_ST	Q92934	BAD	P31749	AKT1	S10	P9Q	9	Missense	proximal	-1	no	8.827	8.834	EPSD	ICGC	7.780	Up-regulation
AGC_Akt_AKT1_ST	Q92934	BAD	P31749	AKT1	S10	S15Y	15	Missense	distal	5	no	8.827	8.783	EPSD	ICGC	7.780	Down-regulation
AGC_Akt_AKT1_ST	Q92934	BAD	P31749	AKT1	S17	S15Y	15	Missense	proximal	-2	no	8.321	7.399	EPSD	ICGC	7.780	Loss
AGC_Akt_AKT1_ST	Q92934	BAD	P31749	AKT1	S75	R72S	72	Missense	distal	-3	no	15.295	7.519	EPSD	ICGC	7.780	Loss
AGC_Akt_AKT1_ST	Q92934	BAD	P31749	AKT1	S75	T80K	80	Missense	distal	5	no	15.295	15.296	EPSD	ICGC	7.780	Up-regulation
AGC_Akt_AKT1_ST	Q92934	BAD	P31749	AKT1	S75	S74G	74	Missense	proximal	-1	no	15.295	15.266	EPSD	ICGC;COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	Q92934	BAD	P31749	AKT1	S97	S99L	99	Missense	proximal	2	no	10.874	10.328	EPSD	ICGC	7.780	Down-regulation
AGC_Akt_AKT1_ST	Q92934	BAD	P31749	AKT1	S97	R94W	94	Missense	distal	-3	no	10.874	1.933	EPSD	ICGC	7.780	Loss
AGC_Akt_AKT1_ST	Q92934	BAD	P31749	AKT1	S99	S99L	99	Missense	central	0	yes	15.195	0.000	PhosphoSitePlus	ICGC	7.780	Loss
AGC_Akt_AKT1_ST	Q92934	BAD	P31749	AKT1	S99	R94W	94	Missense	distal	-5	no	15.195	9.675	PhosphoSitePlus	ICGC	7.780	Down-regulation
AGC_Akt_AKT1_ST	Q92934	BAD	P31749	AKT1	S118	R112S	112	Missense	distal	-6	no	10.696	10.662	EPSD	ICGC	7.780	Down-regulation
AGC_Akt_AKT1_ST	Q92934	BAD	P31749	AKT1	S145	R149L	149	Missense	distal	4	no	9.942	10.120	EPSD	ICGC;COSMIC	7.780	Up-regulation
AGC_Akt_AKT1_ST	Q92934	BAD	P31749	AKT1	S153	R149L	149	Missense	distal	-4	no	8.003	6.794	EPSD	ICGC;COSMIC	7.780	Loss
AGC_Akt_AKT1_ST	Q92934	BAD	P31749	AKT1	S164	S167F	167	Missense	distal	3	no	13.174	13.076	EPSD	ICGC	7.780	Down-regulation
AGC_Akt_AKT1_ST	P09651	HNRNPA1	P31749	AKT1	S6	K3N	3	Missense	distal	-3	no	9.809	6.852	EPSD	ICGC;COSMIC	7.780	Loss
AGC_Akt_AKT1_ST	P09651	HNRNPA1	P31749	AKT1	S6	E9K	9	Missense	distal	3	no	9.809	9.852	EPSD	ICGC;COSMIC	7.780	Up-regulation
AGC_Akt_AKT1_ST	P09651	HNRNPA1	P31749	AKT1	S6	Q12H	12	Missense	distal	6	no	9.809	9.760	EPSD	ICGC;COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	P09651	HNRNPA1	P31749	AKT1	S6	S6F	6	Missense	central	0	yes	9.809	0.000	EPSD	ICGC;COSMIC	7.780	Loss
AGC_Akt_AKT1_ST	P09651	HNRNPA1	P31749	AKT1	S91	D94V	94	Missense	distal	3	no	12.353	12.375	EPSD	ICGC;COSMIC	7.780	Up-regulation
AGC_Akt_AKT1_ST	P09651	HNRNPA1	P31749	AKT1	S91	R88I	88	Missense	distal	-3	no	12.353	5.272	EPSD	ICGC;COSMIC	7.780	Loss
AGC_Akt_AKT1_ST	P09651	HNRNPA1	P31749	AKT1	S91	S91C	91	Missense	central	0	yes	12.353	0.000	EPSD	ICGC;COSMIC	7.780	Loss
AGC_Akt_AKT1_ST	P09651	HNRNPA1	P31749	AKT1	S91	R97K	97	Missense	distal	6	no	12.353	12.365	EPSD	ICGC	7.780	Up-regulation
AGC_Akt_AKT1_ST	P09651	HNRNPA1	P31749	AKT1	S91	A89V	89	Missense	proximal	-2	no	12.353	11.615	EPSD	ICGC	7.780	Down-regulation
AGC_Akt_AKT1_ST	P09651	HNRNPA1	P31749	AKT1	S95	D94V	94	Missense	proximal	-1	no	13.995	14.008	EPSD	ICGC;COSMIC	7.780	Up-regulation
AGC_Akt_AKT1_ST	P09651	HNRNPA1	P31749	AKT1	S95	R88I	88	Missense	distal	-7	no	13.995	13.567	EPSD	ICGC;COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	P09651	HNRNPA1	P31749	AKT1	S95	S91C	91	Missense	distal	-4	no	13.995	12.402	EPSD	ICGC;COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	P09651	HNRNPA1	P31749	AKT1	S95	R97K	97	Missense	proximal	2	no	13.995	14.183	EPSD	ICGC	7.780	Up-regulation
AGC_Akt_AKT1_ST	P09651	HNRNPA1	P31749	AKT1	S95	H101N	101	Missense	distal	6	no	13.995	14.048	EPSD	ICGC;COSMIC	7.780	Up-regulation
AGC_Akt_AKT1_ST	P09651	HNRNPA1	P31749	AKT1	S95	A89V	89	Missense	distal	-6	no	13.995	13.975	EPSD	ICGC	7.780	Down-regulation
AGC_Akt_AKT1_ST	P84022	SMAD3	P31749	AKT1	T388	P393T	393	Missense	distal	5	no	10.153	10.206	EPSD	ICGC;COSMIC	7.780	Up-regulation
AGC_Akt_AKT1_ST	P84022	SMAD3	P31749	AKT1	S416	L411F	411	Missense	distal	-5	no	7.226	7.831	EPSD	ICGC;COSMIC	7.780	Gain
AGC_Akt_AKT1_ST	P84022	SMAD3	P31749	AKT1	S423	S422F	422	Missense	proximal	-1	no	12.093	12.058	EPSD	ICGC;COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	P84022	SMAD3	P31749	AKT1	S423	S423N	423	Missense	central	0	yes	12.093	0.000	EPSD	ICGC;COSMIC	7.780	Loss
AGC_Akt_AKT1_ST	P84022	SMAD3	P31749	AKT1	S423	R420S	420	Missense	distal	-3	no	12.093	4.316	EPSD	ICGC;COSMIC	7.780	Loss
AGC_Akt_AKT1_ST	P84022	SMAD3	P31749	AKT1	S425	S423T	423	Missense	proximal	-2	no	9.123	9.057	EPSD	ICGC;COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	P84022	SMAD3	P31749	AKT1	S425	S422F	422	Missense	distal	-3	no	9.123	11.305	EPSD	ICGC;COSMIC	7.780	Up-regulation
AGC_Akt_AKT1_ST	P84022	SMAD3	P31749	AKT1	S425	S423N	423	Missense	proximal	-2	no	9.123	8.437	EPSD	ICGC;COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	P84022	SMAD3	P31749	AKT1	S425	R420S	420	Missense	distal	-5	no	9.123	4.653	EPSD	ICGC;COSMIC	7.780	Loss
AGC_Akt_AKT1_ST	P18031	PTPN1	P31749	AKT1	S50	R45S	45	Missense	distal	-5	no	15.185	10.715	PhosphoSitePlus	ICGC	7.780	Down-regulation
AGC_Akt_AKT1_ST	P18031	PTPN1	P31749	AKT1	T224	S222F	222	Missense	proximal	-2	no	9.882	9.016	EPSD	ICGC;COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	P68400	CSNK2A1	P31749	AKT1	T13	H18Q	18	Missense	distal	5	no	15.151	15.174	PhosphoSitePlus	ICGC	7.780	Up-regulation
AGC_Akt_AKT1_ST	P68400	CSNK2A1	P31749	AKT1	S194	P200H	200	Missense	distal	6	no	10.046	10.019	EPSD	ICGC;COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	P68400	CSNK2A1	P31749	AKT1	S194	Y188H	188	Missense	distal	-6	no	10.046	10.020	EPSD	ICGC;COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	P68400	CSNK2A1	P31749	AKT1	S336	D330E	330	Missense	distal	-6	no	11.358	11.430	EPSD	ICGC	7.780	Up-regulation
AGC_Akt_AKT1_ST	P68400	CSNK2A1	P31749	AKT1	S336	S336L	336	Missense	central	0	yes	11.358	0.000	EPSD	ICGC	7.780	Loss
AGC_Akt_AKT1_ST	P68400	CSNK2A1	P31749	AKT1	S336	R333L	333	Missense	distal	-3	no	11.358	4.364	EPSD	ICGC;COSMIC	7.780	Loss
AGC_Akt_AKT1_ST	P68400	CSNK2A1	P31749	AKT1	S338	T344M	344	Missense	distal	6	no	9.548	9.428	EPSD	ICGC;COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	P68400	CSNK2A1	P31749	AKT1	S338	S336L	336	Missense	proximal	-2	no	9.548	8.691	EPSD	ICGC	7.780	Down-regulation
AGC_Akt_AKT1_ST	P68400	CSNK2A1	P31749	AKT1	S338	R333L	333	Missense	distal	-5	no	9.548	5.421	EPSD	ICGC;COSMIC	7.780	Loss
AGC_Akt_AKT1_ST	Q96HP0	DOCK6	P31749	AKT1	S30	R27W	27	Missense	distal	-3	no	13.110	4.169	EPSD	ICGC	7.780	Loss
AGC_Akt_AKT1_ST	Q96HP0	DOCK6	P31749	AKT1	S30	R29H	29	Missense	proximal	-1	no	13.110	13.065	EPSD	ICGC;COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	Q96HP0	DOCK6	P31749	AKT1	S30	Q24K	24	Missense	distal	-6	no	13.110	13.180	EPSD	ICGC	7.780	Up-regulation
AGC_Akt_AKT1_ST	Q96HP0	DOCK6	P31749	AKT1	S30	S35F	35	Missense	distal	5	no	13.110	13.037	EPSD	ICGC	7.780	Down-regulation
AGC_Akt_AKT1_ST	Q96HP0	DOCK6	P31749	AKT1	S30	S32F	32	Missense	proximal	2	no	13.110	12.533	EPSD	ICGC	7.780	Down-regulation
AGC_Akt_AKT1_ST	Q96HP0	DOCK6	P31749	AKT1	S30	K23E	23	Missense	distal	-7	no	13.110	12.917	EPSD	ICGC;COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	Q96HP0	DOCK6	P31749	AKT1	S40	S35F	35	Missense	distal	-5	no	12.727	13.676	EPSD	ICGC	7.780	Up-regulation
AGC_Akt_AKT1_ST	Q96HP0	DOCK6	P31749	AKT1	S40	S42F	42	Missense	proximal	2	no	12.727	12.150	EPSD	ICGC;COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	Q96HP0	DOCK6	P31749	AKT1	S41	S35F	35	Missense	distal	-6	no	9.585	9.510	EPSD	ICGC	7.780	Down-regulation
AGC_Akt_AKT1_ST	Q96HP0	DOCK6	P31749	AKT1	S41	S42F	42	Missense	proximal	1	no	9.585	9.603	EPSD	ICGC;COSMIC	7.780	Up-regulation
AGC_Akt_AKT1_ST	Q96HP0	DOCK6	P31749	AKT1	S42	S35F	35	Missense	distal	-7	no	11.668	11.391	EPSD	ICGC	7.780	Down-regulation
AGC_Akt_AKT1_ST	Q96HP0	DOCK6	P31749	AKT1	S42	S42F	42	Missense	central	0	yes	11.668	0.000	EPSD	ICGC;COSMIC	7.780	Loss
AGC_Akt_AKT1_ST	Q96HP0	DOCK6	P31749	AKT1	S176	S178F	178	Missense	proximal	2	no	13.373	12.796	EPSD	ICGC	7.780	Down-regulation
AGC_Akt_AKT1_ST	Q96HP0	DOCK6	P31749	AKT1	S178	S178F	178	Missense	central	0	yes	9.978	0.000	EPSD	ICGC	7.780	Loss
AGC_Akt_AKT1_ST	Q96HP0	DOCK6	P31749	AKT1	S189	S190I	190	Missense	proximal	1	no	8.651	8.402	EPSD	ICGC;COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	Q96HP0	DOCK6	P31749	AKT1	S439	A437E	437	Missense	proximal	-2	no	9.361	9.404	EPSD	ICGC	7.780	Up-regulation
AGC_Akt_AKT1_ST	Q96HP0	DOCK6	P31749	AKT1	S483	L486M	486	Missense	distal	3	no	12.700	12.712	EPSD	ICGC	7.780	Up-regulation
AGC_Akt_AKT1_ST	Q96HP0	DOCK6	P31749	AKT1	S483	M479L	479	Missense	distal	-4	no	12.700	12.485	EPSD	ICGC	7.780	Down-regulation
AGC_Akt_AKT1_ST	Q96HP0	DOCK6	P31749	AKT1	S484	L486M	486	Missense	proximal	2	no	11.184	11.313	EPSD	ICGC	7.780	Up-regulation
AGC_Akt_AKT1_ST	Q96HP0	DOCK6	P31749	AKT1	S484	P482L	482	Missense	proximal	-2	no	11.184	11.152	EPSD	ICGC;COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	Q96HP0	DOCK6	P31749	AKT1	S484	M479L	479	Missense	distal	-5	no	11.184	11.580	EPSD	ICGC	7.780	Up-regulation
AGC_Akt_AKT1_ST	Q96HP0	DOCK6	P31749	AKT1	T493	L486M	486	Missense	distal	-7	no	14.032	14.050	EPSD	ICGC	7.780	Up-regulation
AGC_Akt_AKT1_ST	Q96HP0	DOCK6	P31749	AKT1	S872	R877S	877	Missense	distal	5	no	11.378	11.370	EPSD	ICGC	7.780	Down-regulation
AGC_Akt_AKT1_ST	Q96HP0	DOCK6	P31749	AKT1	S872	A871E	871	Missense	proximal	-1	no	11.378	11.384	EPSD	ICGC	7.780	Up-regulation
AGC_Akt_AKT1_ST	Q96HP0	DOCK6	P31749	AKT1	S872	R865H	865	Missense	distal	-7	no	11.378	11.076	EPSD	ICGC;COSMIC;GDSC	7.780	Down-regulation
AGC_Akt_AKT1_ST	Q96HP0	DOCK6	P31749	AKT1	S872	R877C	877	Missense	distal	5	no	11.378	11.251	EPSD	ICGC;COSMIC;GDSC	7.780	Down-regulation
AGC_Akt_AKT1_ST	Q96HP0	DOCK6	P31749	AKT1	S872	G866D	866	Missense	distal	-6	no	11.378	11.339	EPSD	ICGC	7.780	Down-regulation
AGC_Akt_AKT1_ST	Q96HP0	DOCK6	P31749	AKT1	S880	R877S	877	Missense	distal	-3	no	12.286	4.509	EPSD	ICGC	7.780	Loss
AGC_Akt_AKT1_ST	Q96HP0	DOCK6	P31749	AKT1	S880	R877C	877	Missense	distal	-3	no	12.286	6.112	EPSD	ICGC;COSMIC;GDSC	7.780	Loss
AGC_Akt_AKT1_ST	Q96HP0	DOCK6	P31749	AKT1	S882	R877S	877	Missense	distal	-5	no	11.961	7.491	EPSD	ICGC	7.780	Loss
AGC_Akt_AKT1_ST	Q96HP0	DOCK6	P31749	AKT1	S882	R877C	877	Missense	distal	-5	no	11.961	7.884	EPSD	ICGC;COSMIC;GDSC	7.780	Down-regulation
AGC_Akt_AKT1_ST	Q96HP0	DOCK6	P31749	AKT1	S1194	D1199E	1199	Missense	distal	5	no	15.967	16.009	PhosphoSitePlus	ICGC	7.780	Up-regulation
AGC_Akt_AKT1_ST	Q96HP0	DOCK6	P31749	AKT1	S1194	R1191S	1191	Missense	distal	-3	no	15.967	8.190	PhosphoSitePlus	ICGC	7.780	Down-regulation
AGC_Akt_AKT1_ST	Q96HP0	DOCK6	P31749	AKT1	S1308	K1312R	1312	Missense	distal	4	no	12.737	12.771	EPSD	ICGC	7.780	Up-regulation
AGC_Akt_AKT1_ST	Q96HP0	DOCK6	P31749	AKT1	S2036	T2029N	2029	Missense	distal	-7	no	7.860	7.696	EPSD	ICGC	7.780	Loss
AGC_Akt_AKT1_ST	P62424	RPL7A	P31749	AKT1	T106	A99T	99	Missense	distal	-7	no	12.130	12.330	PhosphoSitePlus	ICGC;COSMIC	7.780	Up-regulation
AGC_Akt_AKT1_ST	P22736	NR4A1	P31749	AKT1	T174	Y167F	167	Missense	distal	-7	no	9.744	9.673	EPSD	ICGC;COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	P22736	NR4A1	P31749	AKT1	S341	R345W	345	Missense	distal	4	no	12.553	12.800	EPSD	ICGC;COSMIC;GDSC;CCLE	7.780	Up-regulation
AGC_Akt_AKT1_ST	P22736	NR4A1	P31749	AKT1	S341	R345L	345	Missense	distal	4	no	12.553	12.731	EPSD	ICGC	7.780	Up-regulation
AGC_Akt_AKT1_ST	P22736	NR4A1	P31749	AKT1	S351	R345W	345	Missense	distal	-6	no	14.750	14.602	PhosphoSitePlus	ICGC;COSMIC;GDSC;CCLE	7.780	Down-regulation
AGC_Akt_AKT1_ST	P22736	NR4A1	P31749	AKT1	S351	R345L	345	Missense	distal	-6	no	14.750	14.665	PhosphoSitePlus	ICGC	7.780	Down-regulation
AGC_Akt_AKT1_ST	P22736	NR4A1	P31749	AKT1	S351	P357S	357	Missense	distal	6	no	14.750	14.843	PhosphoSitePlus	ICGC;COSMIC	7.780	Up-regulation
AGC_Akt_AKT1_ST	P22736	NR4A1	P31749	AKT1	S351	D358N	358	Missense	distal	7	no	14.750	14.791	PhosphoSitePlus	ICGC;COSMIC;CCLE	7.780	Up-regulation
AGC_Akt_AKT1_ST	P42858	HTT	P31749	AKT1	S417	I420V	420	Missense	distal	3	no	11.391	11.432	EPSD	ICGC;COSMIC	7.780	Up-regulation
AGC_Akt_AKT1_ST	P42858	HTT	P31749	AKT1	S417	G412C	412	Missense	distal	-5	no	11.391	11.379	EPSD	ICGC;COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	P42858	HTT	P31749	AKT1	S419	I420V	420	Missense	proximal	1	no	17.050	17.297	PhosphoSitePlus	ICGC;COSMIC	7.780	Up-regulation
AGC_Akt_AKT1_ST	P42858	HTT	P31749	AKT1	S419	G412C	412	Missense	distal	-7	no	17.050	16.813	PhosphoSitePlus	ICGC;COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	P42858	HTT	P31749	AKT1	S463	S459L	459	Missense	distal	-4	no	9.890	8.766	EPSD	ICGC;COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	P42858	HTT	P31749	AKT1	S621	E615G	615	Missense	distal	-6	no	11.834	11.800	EPSD	ICGC;COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	P42858	HTT	P31749	AKT1	S640	S634G	634	Missense	distal	-6	no	12.805	12.726	EPSD	ICGC;COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	P42858	HTT	P31749	AKT1	S640	P639S	639	Missense	proximal	-1	no	12.805	12.834	EPSD	ICGC;COSMIC	7.780	Up-regulation
AGC_Akt_AKT1_ST	P42858	HTT	P31749	AKT1	S642	P639S	639	Missense	distal	-3	no	10.193	9.056	EPSD	ICGC;COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	P42858	HTT	P31749	AKT1	S689	F692L	692	Missense	distal	3	no	11.547	11.548	EPSD	ICGC	7.780	Up-regulation
AGC_Akt_AKT1_ST	P42858	HTT	P31749	AKT1	S689	A690S	690	Missense	proximal	1	no	11.547	11.620	EPSD	ICGC;COSMIC	7.780	Up-regulation
AGC_Akt_AKT1_ST	P42858	HTT	P31749	AKT1	T898	G893R	893	Missense	distal	-5	no	4.889	8.953	EPSD	ICGC;COSMIC	7.780	Gain
AGC_Akt_AKT1_ST	P42858	HTT	P31749	AKT1	S1111	W1109C	1109	Missense	proximal	-2	no	9.187	8.977	EPSD	ICGC;COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	P42858	HTT	P31749	AKT1	S1111	L1105M	1105	Missense	distal	-6	no	9.187	9.175	EPSD	ICGC;COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	P42858	HTT	P31749	AKT1	S1111	P1117Q	1117	Missense	distal	6	no	9.187	9.208	EPSD	ICGC;COSMIC	7.780	Up-regulation
AGC_Akt_AKT1_ST	P42858	HTT	P31749	AKT1	T1260	Q1257R	1257	Missense	distal	-3	no	3.946	11.157	EPSD	ICGC;COSMIC	7.780	Gain
AGC_Akt_AKT1_ST	P42858	HTT	P31749	AKT1	S1349	G1346V	1346	Missense	distal	-3	no	8.613	8.504	EPSD	ICGC	7.780	Down-regulation
AGC_Akt_AKT1_ST	P42858	HTT	P31749	AKT1	S1862	P1858L	1858	Missense	distal	-4	no	8.434	8.046	EPSD	ICGC;COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	P42858	HTT	P31749	AKT1	S1864	P1858L	1858	Missense	distal	-6	no	11.103	11.117	EPSD	ICGC;COSMIC	7.780	Up-regulation
AGC_Akt_AKT1_ST	P42858	HTT	P31749	AKT1	S1865	P1858L	1858	Missense	distal	-7	no	8.516	8.476	EPSD	ICGC;COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	P42858	HTT	P31749	AKT1	S2065	S2072I	2072	Missense	distal	7	no	8.055	7.957	EPSD	ICGC	7.780	Down-regulation
AGC_Akt_AKT1_ST	P42858	HTT	P31749	AKT1	S2065	L2058M	2058	Missense	distal	-7	no	8.055	8.072	EPSD	ICGC;COSMIC	7.780	Up-regulation
AGC_Akt_AKT1_ST	P42858	HTT	P31749	AKT1	T2066	S2072I	2072	Missense	distal	6	no	13.354	13.189	EPSD	ICGC	7.780	Down-regulation
AGC_Akt_AKT1_ST	P42858	HTT	P31749	AKT1	S2114	E2118K	2118	Missense	distal	4	no	12.204	12.104	EPSD	ICGC;COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	P42858	HTT	P31749	AKT1	S2114	A2120T	2120	Missense	distal	6	no	12.204	12.307	EPSD	ICGC;COSMIC	7.780	Up-regulation
AGC_Akt_AKT1_ST	P42858	HTT	P31749	AKT1	S2114	A2120S	2120	Missense	distal	6	no	12.204	12.286	EPSD	ICGC	7.780	Up-regulation
AGC_Akt_AKT1_ST	P42858	HTT	P31749	AKT1	T2455	R2461H	2461	Missense	distal	6	no	8.834	8.715	EPSD	ICGC;COSMIC;CCLE	7.780	Down-regulation
AGC_Akt_AKT1_ST	P05787	KRT8	P31749	AKT1	S21	R23C	23	Missense	proximal	2	no	12.497	11.844	EPSD	ICGC;COSMIC;GDSC	7.780	Down-regulation
AGC_Akt_AKT1_ST	P05787	KRT8	P31749	AKT1	T26	R23C	23	Missense	distal	-3	no	12.661	6.488	EPSD	ICGC;COSMIC;GDSC	7.780	Loss
AGC_Akt_AKT1_ST	P05787	KRT8	P31749	AKT1	S35	S36W	36	Missense	proximal	1	no	12.612	12.464	EPSD	ICGC	7.780	Down-regulation
AGC_Akt_AKT1_ST	P05787	KRT8	P31749	AKT1	S35	S37C	37	Missense	proximal	2	no	12.612	11.788	EPSD	ICGC;COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	P05787	KRT8	P31749	AKT1	S37	S36W	36	Missense	proximal	-1	no	8.163	8.113	EPSD	ICGC	7.780	Down-regulation
AGC_Akt_AKT1_ST	P05787	KRT8	P31749	AKT1	S37	S37C	37	Missense	central	0	yes	8.163	0.000	EPSD	ICGC;COSMIC	7.780	Loss
AGC_Akt_AKT1_ST	P05787	KRT8	P31749	AKT1	S43	S36W	36	Missense	distal	-7	no	11.867	11.500	EPSD	ICGC	7.780	Down-regulation
AGC_Akt_AKT1_ST	P05787	KRT8	P31749	AKT1	S43	G48R	48	Missense	distal	5	no	11.867	11.938	EPSD	ICGC;COSMIC	7.780	Up-regulation
AGC_Akt_AKT1_ST	P05787	KRT8	P31749	AKT1	S43	S37C	37	Missense	distal	-6	no	11.867	11.721	EPSD	ICGC;COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	P05787	KRT8	P31749	AKT1	S280	R275Q	275	Missense	distal	-5	no	9.529	5.301	EPSD	ICGC;COSMIC	7.780	Loss
AGC_Akt_AKT1_ST	P05787	KRT8	P31749	AKT1	T305	R301W	301	Missense	distal	-4	no	12.294	10.744	EPSD	ICGC;COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	P05787	KRT8	P31749	AKT1	S404	S410G	410	Missense	distal	6	no	11.574	11.469	EPSD	ICGC;COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	P05787	KRT8	P31749	AKT1	S417	S410G	410	Missense	distal	-7	no	9.387	9.201	EPSD	ICGC;COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	P05787	KRT8	P31749	AKT1	S417	S424I	424	Missense	distal	7	no	9.387	9.289	EPSD	ICGC	7.780	Down-regulation
AGC_Akt_AKT1_ST	P05787	KRT8	P31749	AKT1	S475	S477A	477	Missense	proximal	2	no	9.810	9.434	EPSD	ICGC;COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	P05787	KRT8	P31749	AKT1	S475	P482L	482	Missense	distal	7	no	9.810	9.802	EPSD	ICGC;COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	P40818	USP8	P31749	AKT1	S14	D19Y	19	Missense	distal	5	no	8.128	8.160	EPSD	ICGC;COSMIC	7.780	Up-regulation
AGC_Akt_AKT1_ST	P40818	USP8	P31749	AKT1	S32	T33N	33	Missense	proximal	1	no	8.807	8.525	EPSD	ICGC;COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	P40818	USP8	P31749	AKT1	S425	E420G	420	Missense	distal	-5	no	10.780	10.810	EPSD	ICGC	7.780	Up-regulation
AGC_Akt_AKT1_ST	P40818	USP8	P31749	AKT1	S427	S434F	434	Missense	distal	7	no	11.043	10.969	EPSD	ICGC;COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	P40818	USP8	P31749	AKT1	S427	E420G	420	Missense	distal	-7	no	11.043	11.007	EPSD	ICGC	7.780	Down-regulation
AGC_Akt_AKT1_ST	P40818	USP8	P31749	AKT1	T577	P578T	578	Missense	proximal	1	no	9.779	10.128	EPSD	ICGC;COSMIC	7.780	Up-regulation
AGC_Akt_AKT1_ST	P40818	USP8	P31749	AKT1	T623	E627K	627	Missense	distal	4	no	10.471	10.370	EPSD	ICGC	7.780	Down-regulation
AGC_Akt_AKT1_ST	P40818	USP8	P31749	AKT1	T623	T618S	618	Missense	distal	-5	no	10.471	9.731	EPSD	ICGC;COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	P40818	USP8	P31749	AKT1	T623	T626N	626	Missense	distal	3	no	10.471	10.416	EPSD	ICGC;COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	P40818	USP8	P31749	AKT1	S641	A639S	639	Missense	proximal	-2	no	11.629	12.081	EPSD	ICGC	7.780	Up-regulation
AGC_Akt_AKT1_ST	P40818	USP8	P31749	AKT1	T673	H670R	670	Missense	distal	-3	no	7.215	11.914	EPSD	ICGC;COSMIC	7.780	Gain
AGC_Akt_AKT1_ST	P40818	USP8	P31749	AKT1	S711	R706W	706	Missense	distal	-5	no	14.396	8.876	EPSD	ICGC;COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	P40818	USP8	P31749	AKT1	S711	A704S	704	Missense	distal	-7	no	14.396	14.545	EPSD	ICGC	7.780	Up-regulation
AGC_Akt_AKT1_ST	P40818	USP8	P31749	AKT1	S718	P720R	720	Missense	proximal	2	no	11.474	11.638	PhosphoSitePlus	ICGC;COSMIC	7.780	Up-regulation
AGC_Akt_AKT1_ST	P40818	USP8	P31749	AKT1	S718	I722K	722	Missense	distal	4	no	11.474	11.190	PhosphoSitePlus	ICGC;COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	P40818	USP8	P31749	AKT1	T723	P720R	720	Missense	distal	-3	no	3.580	10.220	EPSD	ICGC;COSMIC	7.780	Gain
AGC_Akt_AKT1_ST	P40818	USP8	P31749	AKT1	T735	V736A	736	Missense	proximal	1	no	11.383	11.311	EPSD	ICGC;COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	P40818	USP8	P31749	AKT1	T735	R742L	742	Missense	distal	7	no	11.383	11.309	EPSD	ICGC;COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	P40818	USP8	P31749	AKT1	T737	V736A	736	Missense	proximal	-1	no	9.216	9.230	EPSD	ICGC;COSMIC	7.780	Up-regulation
AGC_Akt_AKT1_ST	P40818	USP8	P31749	AKT1	T737	R742L	742	Missense	distal	5	no	9.216	9.142	EPSD	ICGC;COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	P40818	USP8	P31749	AKT1	S846	I845V	845	Missense	proximal	-1	no	11.203	11.218	EPSD	ICGC	7.780	Up-regulation
AGC_Akt_AKT1_ST	P40818	USP8	P31749	AKT1	S846	Y844C	844	Missense	proximal	-2	no	11.203	10.472	EPSD	ICGC;COSMIC;GDSC	7.780	Down-regulation
AGC_Akt_AKT1_ST	P40818	USP8	P31749	AKT1	S972	L977V	977	Missense	distal	5	no	11.301	11.308	EPSD	ICGC;COSMIC	7.780	Up-regulation
AGC_Akt_AKT1_ST	P40818	USP8	P31749	AKT1	S972	D979Y	979	Missense	distal	7	no	11.301	11.335	EPSD	ICGC	7.780	Up-regulation
AGC_Akt_AKT1_ST	Q969H0	FBXW7	P31749	AKT1	S18	R20I	20	Missense	proximal	2	no	11.004	10.519	EPSD	ICGC;COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	Q969H0	FBXW7	P31749	AKT1	S18	R12I	12	Missense	distal	-6	no	11.004	10.849	EPSD	ICGC;COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	Q969H0	FBXW7	P31749	AKT1	S18	P23S	23	Missense	distal	5	no	11.004	11.056	EPSD	ICGC;COSMIC	7.780	Up-regulation
AGC_Akt_AKT1_ST	Q969H0	FBXW7	P31749	AKT1	S25	P23S	23	Missense	proximal	-2	no	7.248	8.073	EPSD	ICGC;COSMIC	7.780	Gain
AGC_Akt_AKT1_ST	Q969H0	FBXW7	P31749	AKT1	S227	I225M	225	Missense	proximal	-2	no	15.464	15.865	PhosphoSitePlus	ICGC	7.780	Up-regulation
AGC_Akt_AKT1_ST	Q969H0	FBXW7	P31749	AKT1	S227	R223S	223	Missense	distal	-4	no	15.464	15.378	PhosphoSitePlus	ICGC	7.780	Down-regulation
AGC_Akt_AKT1_ST	Q969H0	FBXW7	P31749	AKT1	S227	T226I	226	Missense	proximal	-1	no	15.464	15.408	PhosphoSitePlus	ICGC;GDSC;CCLE	7.780	Down-regulation
AGC_Akt_AKT1_ST	Q969H0	FBXW7	P31749	AKT1	S227	R224Q	224	Missense	distal	-3	no	15.464	8.252	PhosphoSitePlus	ICGC;COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	Q969H0	FBXW7	P31749	AKT1	S372	G368R	368	Missense	distal	-4	no	8.784	9.599	EPSD	ICGC;COSMIC	7.780	Up-regulation
AGC_Akt_AKT1_ST	Q969H0	FBXW7	P31749	AKT1	S372	V375L	375	Missense	distal	3	no	8.784	8.776	EPSD	ICGC;COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	Q969H0	FBXW7	P31749	AKT1	T692	E693K	693	Missense	proximal	1	no	12.179	12.343	EPSD	ICGC;COSMIC	7.780	Up-regulation
AGC_Akt_AKT1_ST	Q969H0	FBXW7	P31749	AKT1	T692	G687E	687	Missense	distal	-5	no	12.179	12.149	EPSD	ICGC;COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	Q04912	MST1R	P31749	AKT1	S217	P213T	213	Missense	distal	-4	no	11.885	12.677	EPSD	ICGC	7.780	Up-regulation
AGC_Akt_AKT1_ST	Q04912	MST1R	P31749	AKT1	S217	R220C	220	Missense	distal	3	no	11.885	11.724	EPSD	ICGC;COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	P45880	VDAC2	P31749	AKT1	T7	M12V	12	Missense	distal	5	no	8.183	8.180	EPSD	ICGC;COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	P45880	VDAC2	P31749	AKT1	T7	H4Y	4	Missense	distal	-3	no	8.183	5.293	EPSD	ICGC;COSMIC	7.780	Loss
AGC_Akt_AKT1_ST	P45880	VDAC2	P31749	AKT1	T7	R10L	10	Missense	distal	3	no	8.183	8.102	EPSD	ICGC;COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	P45880	VDAC2	P31749	AKT1	S48	D41N	41	Missense	distal	-7	no	9.494	9.752	PhosphoSitePlus	ICGC;COSMIC	7.780	Up-regulation
AGC_Akt_AKT1_ST	P45880	VDAC2	P31749	AKT1	S48	G49C	49	Missense	proximal	1	no	9.494	9.416	PhosphoSitePlus	ICGC;COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	P45880	VDAC2	P31749	AKT1	S48	S53L	53	Missense	distal	5	no	9.494	9.428	PhosphoSitePlus	ICGC;COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	P45880	VDAC2	P31749	AKT1	S48	D41G	41	Missense	distal	-7	no	9.494	9.680	PhosphoSitePlus	ICGC;COSMIC	7.780	Up-regulation
AGC_Akt_AKT1_ST	P45880	VDAC2	P31749	AKT1	S48	S55P	55	Missense	distal	7	no	9.494	9.436	PhosphoSitePlus	ICGC	7.780	Down-regulation
AGC_Akt_AKT1_ST	P45880	VDAC2	P31749	AKT1	S48	V50M	50	Missense	proximal	2	no	9.494	9.616	PhosphoSitePlus	ICGC	7.780	Up-regulation
AGC_Akt_AKT1_ST	P63000	RAC1	P31749	AKT1	S71	Y72C	72	Missense	proximal	1	no	13.601	13.225	PhosphoSitePlus	ICGC;COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	P63000	RAC1	P31749	AKT1	T125	E127V	127	Missense	proximal	2	no	8.880	8.531	EPSD	ICGC;COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	P63000	RAC1	P31749	AKT1	T125	E127K	127	Missense	proximal	2	no	8.880	9.085	EPSD	ICGC;COSMIC	7.780	Up-regulation
AGC_Akt_AKT1_ST	Q15121	PEA15	P31749	AKT1	S104	P103S	103	Missense	proximal	-1	no	12.656	12.685	EPSD	ICGC;COSMIC	7.780	Up-regulation
AGC_Akt_AKT1_ST	P49840	GSK3A	P31749	AKT1	T101	G98R	98	Missense	distal	-3	no	4.930	11.686	EPSD	ICGC	7.780	Gain
AGC_Akt_AKT1_ST	P04792	HSPB1	P31749	AKT1	S9	E3Q	3	Missense	distal	-6	no	10.774	10.771	EPSD	ICGC;COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	P04792	HSPB1	P31749	AKT1	S9	T2I	2	Missense	distal	-7	no	10.774	10.352	EPSD	ICGC;COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	P53804	TTC3	P31749	AKT1	S378	I381V	381	Missense	distal	3	no	12.555	12.597	PhosphoSitePlus	ICGC;COSMIC	7.780	Up-regulation
AGC_Akt_AKT1_ST	P53804	TTC3	P31749	AKT1	S378	P380A	380	Missense	proximal	2	no	12.555	12.516	PhosphoSitePlus	ICGC;COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	P53804	TTC3	P31749	AKT1	S378	Y372D	372	Missense	distal	-6	no	12.555	12.496	PhosphoSitePlus	ICGC	7.780	Down-regulation
AGC_Akt_AKT1_ST	P53804	TTC3	P31749	AKT1	S1915	V1920M	1920	Missense	distal	5	no	9.870	9.873	EPSD	ICGC	7.780	Up-regulation
AGC_Akt_AKT1_ST	P53804	TTC3	P31749	AKT1	S1927	V1920M	1920	Missense	distal	-7	no	8.475	8.536	EPSD	ICGC	7.780	Up-regulation
AGC_Akt_AKT1_ST	P56270	MAZ	P31749	AKT1	S300	R296P	296	Missense	distal	-4	no	7.856	7.034	EPSD	ICGC;COSMIC	7.780	Loss
AGC_Akt_AKT1_ST	P56270	MAZ	P31749	AKT1	S300	S300N	300	Missense	central	0	yes	7.856	0.000	EPSD	ICGC;COSMIC	7.780	Loss
AGC_Akt_AKT1_ST	P56270	MAZ	P31749	AKT1	T385	V386I	386	Missense	proximal	1	no	14.332	14.085	PhosphoSitePlus	ICGC;COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	P09601	HMOX1	P31749	AKT1	S188	V195A	195	Missense	distal	7	no	16.283	16.287	PhosphoSitePlus	ICGC;COSMIC	7.780	Up-regulation
AGC_Akt_AKT1_ST	P09601	HMOX1	P31749	AKT1	S229	D227Y	227	Missense	proximal	-2	no	7.690	8.161	EPSD	ICGC	7.780	Gain
AGC_Akt_AKT1_ST	Q13009	TIAM1	P31749	AKT1	T26	R31H	31	Missense	distal	5	no	11.882	11.808	EPSD	ICGC;COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	Q13009	TIAM1	P31749	AKT1	T26	G22W	22	Missense	distal	-4	no	11.882	11.148	EPSD	ICGC;COSMIC;GDSC;CCLE	7.780	Down-regulation
AGC_Akt_AKT1_ST	Q13009	TIAM1	P31749	AKT1	T26	H25Q	25	Missense	proximal	-1	no	11.882	11.894	EPSD	ICGC	7.780	Up-regulation
AGC_Akt_AKT1_ST	Q13009	TIAM1	P31749	AKT1	T26	R23C	23	Missense	distal	-3	no	11.882	5.709	EPSD	ICGC;GDSC	7.780	Loss
AGC_Akt_AKT1_ST	Q13009	TIAM1	P31749	AKT1	T26	R28S	28	Missense	proximal	2	no	11.882	12.054	EPSD	ICGC	7.780	Up-regulation
AGC_Akt_AKT1_ST	Q13009	TIAM1	P31749	AKT1	S33	R31H	31	Missense	proximal	-2	no	9.995	9.134	EPSD	ICGC;COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	Q13009	TIAM1	P31749	AKT1	S33	R28S	28	Missense	distal	-5	no	9.995	5.525	EPSD	ICGC	7.780	Loss
AGC_Akt_AKT1_ST	Q13009	TIAM1	P31749	AKT1	S33	R37L	37	Missense	distal	4	no	9.995	10.173	EPSD	ICGC;COSMIC	7.780	Up-regulation
AGC_Akt_AKT1_ST	Q13009	TIAM1	P31749	AKT1	S43	R37L	37	Missense	distal	-6	no	15.019	14.935	EPSD	ICGC;COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	Q13009	TIAM1	P31749	AKT1	S60	S59G	59	Missense	proximal	-1	no	13.091	13.061	EPSD	ICGC;COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	Q13009	TIAM1	P31749	AKT1	S60	S67F	67	Missense	distal	7	no	13.091	13.017	EPSD	ICGC	7.780	Down-regulation
AGC_Akt_AKT1_ST	Q13009	TIAM1	P31749	AKT1	S102	S107Y	107	Missense	distal	5	no	9.939	9.896	EPSD	ICGC;COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	Q13009	TIAM1	P31749	AKT1	S102	T104A	104	Missense	proximal	2	no	9.939	9.638	EPSD	ICGC	7.780	Down-regulation
AGC_Akt_AKT1_ST	Q13009	TIAM1	P31749	AKT1	T104	S107Y	107	Missense	distal	3	no	8.676	8.608	EPSD	ICGC;COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	Q13009	TIAM1	P31749	AKT1	T104	T104A	104	Missense	central	0	yes	8.676	0.000	EPSD	ICGC	7.780	Loss
AGC_Akt_AKT1_ST	Q13009	TIAM1	P31749	AKT1	T104	P110T	110	Missense	distal	6	no	8.676	8.790	EPSD	ICGC;COSMIC	7.780	Up-regulation
AGC_Akt_AKT1_ST	Q13009	TIAM1	P31749	AKT1	S170	D174E	174	Missense	distal	4	no	9.616	9.470	EPSD	ICGC	7.780	Down-regulation
AGC_Akt_AKT1_ST	Q13009	TIAM1	P31749	AKT1	S170	S170F	170	Missense	central	0	yes	9.616	0.000	EPSD	ICGC;COSMIC	7.780	Loss
AGC_Akt_AKT1_ST	Q13009	TIAM1	P31749	AKT1	S170	K167E	167	Missense	distal	-3	no	9.616	7.565	EPSD	ICGC;COSMIC	7.780	Loss
AGC_Akt_AKT1_ST	Q13009	TIAM1	P31749	AKT1	S172	D174E	174	Missense	proximal	2	no	13.600	14.010	EPSD	ICGC	7.780	Up-regulation
AGC_Akt_AKT1_ST	Q13009	TIAM1	P31749	AKT1	S172	S170F	170	Missense	proximal	-2	no	13.600	12.733	EPSD	ICGC;COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	Q13009	TIAM1	P31749	AKT1	S172	K167E	167	Missense	distal	-5	no	13.600	11.902	EPSD	ICGC;COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	Q13009	TIAM1	P31749	AKT1	S224	R228T	228	Missense	distal	4	no	9.607	9.592	EPSD	ICGC	7.780	Down-regulation
AGC_Akt_AKT1_ST	Q13009	TIAM1	P31749	AKT1	S231	R228T	228	Missense	distal	-3	no	11.969	4.948	PhosphoSitePlus	ICGC	7.780	Loss
AGC_Akt_AKT1_ST	Q13009	TIAM1	P31749	AKT1	S311	Q313K	313	Missense	proximal	2	no	7.516	7.822	EPSD	ICGC	7.780	Gain
AGC_Akt_AKT1_ST	Q13009	TIAM1	P31749	AKT1	T319	Q313K	313	Missense	distal	-6	no	11.997	12.067	EPSD	ICGC	7.780	Up-regulation
AGC_Akt_AKT1_ST	Q13009	TIAM1	P31749	AKT1	T319	D322N	322	Missense	distal	3	no	11.997	12.053	EPSD	ICGC	7.780	Up-regulation
AGC_Akt_AKT1_ST	Q13009	TIAM1	P31749	AKT1	T320	Q313K	313	Missense	distal	-7	no	10.112	10.293	EPSD	ICGC	7.780	Up-regulation
AGC_Akt_AKT1_ST	Q13009	TIAM1	P31749	AKT1	T320	D322N	322	Missense	proximal	2	no	10.112	10.442	EPSD	ICGC	7.780	Up-regulation
AGC_Akt_AKT1_ST	Q13009	TIAM1	P31749	AKT1	T320	E327K	327	Missense	distal	7	no	10.112	10.146	EPSD	ICGC;COSMIC	7.780	Up-regulation
AGC_Akt_AKT1_ST	Q13009	TIAM1	P31749	AKT1	S373	S370R	370	Missense	distal	-3	no	0.728	8.504	EPSD	ICGC	7.780	Gain
AGC_Akt_AKT1_ST	Q13009	TIAM1	P31749	AKT1	S456	N451K	451	Missense	distal	-5	no	6.590	8.677	EPSD	ICGC	7.780	Gain
AGC_Akt_AKT1_ST	Q13009	TIAM1	P31749	AKT1	T679	S683F	683	Missense	distal	4	no	9.345	9.541	EPSD	ICGC	7.780	Up-regulation
AGC_Akt_AKT1_ST	Q13009	TIAM1	P31749	AKT1	T679	A681V	681	Missense	proximal	2	no	9.345	9.183	EPSD	ICGC	7.780	Down-regulation
AGC_Akt_AKT1_ST	Q13009	TIAM1	P31749	AKT1	S687	S694Y	694	Missense	distal	7	no	11.534	11.491	EPSD	ICGC;COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	Q13009	TIAM1	P31749	AKT1	S687	S683F	683	Missense	distal	-4	no	11.534	10.366	EPSD	ICGC	7.780	Down-regulation
AGC_Akt_AKT1_ST	Q13009	TIAM1	P31749	AKT1	S687	A681V	681	Missense	distal	-6	no	11.534	11.514	EPSD	ICGC	7.780	Down-regulation
AGC_Akt_AKT1_ST	Q13009	TIAM1	P31749	AKT1	S694	S694Y	694	Missense	central	0	yes	8.523	0.000	EPSD	ICGC;COSMIC	7.780	Loss
AGC_Akt_AKT1_ST	Q13009	TIAM1	P31749	AKT1	S695	S694Y	694	Missense	proximal	-1	no	16.252	16.226	EPSD	ICGC;COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	O15151	MDM4	P31749	AKT1	S342	I349T	349	Missense	distal	7	no	9.130	9.238	EPSD	ICGC;COSMIC	7.780	Up-regulation
AGC_Akt_AKT1_ST	O15151	MDM4	P31749	AKT1	S344	I349T	349	Missense	distal	5	no	8.555	8.652	EPSD	ICGC;COSMIC	7.780	Up-regulation
AGC_Akt_AKT1_ST	Q7Z5H3	ARHGAP22	P31749	AKT1	S14	G20E	20	Missense	distal	6	no	15.608	15.655	EPSD	ICGC;COSMIC	7.780	Up-regulation
AGC_Akt_AKT1_ST	Q7Z5H3	ARHGAP22	P31749	AKT1	S14	R13H	13	Missense	proximal	-1	no	15.608	15.564	EPSD	ICGC;COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	Q7Z5H3	ARHGAP22	P31749	AKT1	S14	Q8K	8	Missense	distal	-6	no	15.608	15.678	EPSD	ICGC	7.780	Up-regulation
AGC_Akt_AKT1_ST	Q7Z5H3	ARHGAP22	P31749	AKT1	S14	S14Y	14	Missense	central	0	yes	15.608	0.000	EPSD	ICGC	7.780	Loss
AGC_Akt_AKT1_ST	Q7Z5H3	ARHGAP22	P31749	AKT1	S16	G20E	20	Missense	distal	4	no	18.130	18.035	PhosphoSitePlus	ICGC;COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	Q7Z5H3	ARHGAP22	P31749	AKT1	S16	R13H	13	Missense	distal	-3	no	18.130	13.432	PhosphoSitePlus	ICGC;COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	Q7Z5H3	ARHGAP22	P31749	AKT1	S16	S14Y	14	Missense	proximal	-2	no	18.130	17.208	PhosphoSitePlus	ICGC	7.780	Down-regulation
AGC_Akt_AKT1_ST	Q7Z5H3	ARHGAP22	P31749	AKT1	S346	T339N	339	Missense	distal	-7	no	11.408	11.244	EPSD	ICGC;COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	Q7Z5H3	ARHGAP22	P31749	AKT1	S346	P352S	352	Missense	distal	6	no	11.408	11.502	EPSD	ICGC	7.780	Up-regulation
AGC_Akt_AKT1_ST	Q7Z5H3	ARHGAP22	P31749	AKT1	S346	V340I	340	Missense	distal	-6	no	11.408	11.363	EPSD	ICGC	7.780	Down-regulation
AGC_Akt_AKT1_ST	Q7Z5H3	ARHGAP22	P31749	AKT1	S395	G398R	398	Missense	distal	3	no	11.981	12.055	EPSD	ICGC;COSMIC	7.780	Up-regulation
AGC_Akt_AKT1_ST	Q7Z5H3	ARHGAP22	P31749	AKT1	S395	A399V	399	Missense	distal	4	no	11.981	12.037	EPSD	ICGC;COSMIC	7.780	Up-regulation
AGC_Akt_AKT1_ST	Q7Z5H3	ARHGAP22	P31749	AKT1	S395	V401G	401	Missense	distal	6	no	11.981	11.990	EPSD	ICGC	7.780	Up-regulation
AGC_Akt_AKT1_ST	Q7Z5H3	ARHGAP22	P31749	AKT1	S395	S394F	394	Missense	proximal	-1	no	11.981	11.946	EPSD	ICGC;COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	Q7Z5H3	ARHGAP22	P31749	AKT1	S395	A390V	390	Missense	distal	-5	no	11.981	11.521	EPSD	ICGC;COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	Q7Z5H3	ARHGAP22	P31749	AKT1	S395	A390T	390	Missense	distal	-5	no	11.981	12.106	EPSD	ICGC;COSMIC	7.780	Up-regulation
AGC_Akt_AKT1_ST	Q7Z5H3	ARHGAP22	P31749	AKT1	S395	S394C	394	Missense	proximal	-1	no	11.981	11.921	EPSD	ICGC;COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	Q7Z5H3	ARHGAP22	P31749	AKT1	S395	R392K	392	Missense	distal	-3	no	11.981	7.461	EPSD	ICGC	7.780	Loss
AGC_Akt_AKT1_ST	Q7Z5H3	ARHGAP22	P31749	AKT1	S437	P435L	435	Missense	proximal	-2	no	7.986	7.954	EPSD	ICGC	7.780	Down-regulation
AGC_Akt_AKT1_ST	Q7Z5H3	ARHGAP22	P31749	AKT1	S437	P442S	442	Missense	distal	5	no	7.986	8.039	EPSD	ICGC	7.780	Up-regulation
AGC_Akt_AKT1_ST	Q7Z5H3	ARHGAP22	P31749	AKT1	S437	G440R	440	Missense	distal	3	no	7.986	8.060	EPSD	ICGC;COSMIC	7.780	Up-regulation
AGC_Akt_AKT1_ST	Q7Z5H3	ARHGAP22	P31749	AKT1	S437	R433W	433	Missense	distal	-4	no	7.986	6.437	EPSD	ICGC;COSMIC	7.780	Loss
AGC_Akt_AKT1_ST	Q7Z5H3	ARHGAP22	P31749	AKT1	S437	S439L	439	Missense	proximal	2	no	7.986	7.440	EPSD	ICGC;COSMIC	7.780	Loss
AGC_Akt_AKT1_ST	Q7Z5H3	ARHGAP22	P31749	AKT1	S439	P435L	435	Missense	distal	-4	no	10.399	10.011	EPSD	ICGC	7.780	Down-regulation
AGC_Akt_AKT1_ST	Q7Z5H3	ARHGAP22	P31749	AKT1	S439	P442S	442	Missense	distal	3	no	10.399	10.480	EPSD	ICGC	7.780	Up-regulation
AGC_Akt_AKT1_ST	Q7Z5H3	ARHGAP22	P31749	AKT1	S439	G440R	440	Missense	proximal	1	no	10.399	10.849	EPSD	ICGC;COSMIC	7.780	Up-regulation
AGC_Akt_AKT1_ST	Q7Z5H3	ARHGAP22	P31749	AKT1	S439	R433W	433	Missense	distal	-6	no	10.399	10.251	EPSD	ICGC;COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	Q7Z5H3	ARHGAP22	P31749	AKT1	S439	S439L	439	Missense	central	0	yes	10.399	0.000	EPSD	ICGC;COSMIC	7.780	Loss
AGC_Akt_AKT1_ST	Q7Z5H3	ARHGAP22	P31749	AKT1	S441	P435L	435	Missense	distal	-6	no	9.968	9.981	EPSD	ICGC	7.780	Up-regulation
AGC_Akt_AKT1_ST	Q7Z5H3	ARHGAP22	P31749	AKT1	S441	S447L	447	Missense	distal	6	no	9.968	9.864	EPSD	ICGC;COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	Q7Z5H3	ARHGAP22	P31749	AKT1	S441	P442S	442	Missense	proximal	1	no	9.968	10.123	EPSD	ICGC	7.780	Up-regulation
AGC_Akt_AKT1_ST	Q7Z5H3	ARHGAP22	P31749	AKT1	S441	G440R	440	Missense	proximal	-1	no	9.968	10.008	EPSD	ICGC;COSMIC	7.780	Up-regulation
AGC_Akt_AKT1_ST	Q7Z5H3	ARHGAP22	P31749	AKT1	S441	S439L	439	Missense	proximal	-2	no	9.968	9.111	EPSD	ICGC;COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	Q7Z5H3	ARHGAP22	P31749	AKT1	S476	R469H	469	Missense	distal	-7	no	12.616	12.314	EPSD	ICGC;COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	Q7Z5H3	ARHGAP22	P31749	AKT1	S476	R472C	472	Missense	distal	-4	no	12.616	10.937	EPSD	ICGC;COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	Q7Z5H3	ARHGAP22	P31749	AKT1	S476	S476L	476	Missense	central	0	yes	12.616	0.000	EPSD	ICGC	7.780	Loss
AGC_Akt_AKT1_ST	Q7Z5H3	ARHGAP22	P31749	AKT1	S636	R632K	632	Missense	distal	-4	no	8.147	8.134	EPSD	ICGC;COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	Q7Z5H3	ARHGAP22	P31749	AKT1	S636	S636P	636	Missense	central	0	yes	8.147	0.000	EPSD	ICGC	7.780	Loss
AGC_Akt_AKT1_ST	Q7Z5H3	ARHGAP22	P31749	AKT1	S636	R637W	637	Missense	proximal	1	no	8.147	7.855	EPSD	ICGC;COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	Q7Z5H3	ARHGAP22	P31749	AKT1	S636	E640K	640	Missense	distal	4	no	8.147	8.047	EPSD	ICGC;COSMIC;GDSC	7.780	Down-regulation
AGC_Akt_AKT1_ST	Q7Z5H3	ARHGAP22	P31749	AKT1	S636	R632S	632	Missense	distal	-4	no	8.147	8.062	EPSD	ICGC;COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	Q7Z5H3	ARHGAP22	P31749	AKT1	S636	R634Q	634	Missense	proximal	-2	no	8.147	7.635	EPSD	ICGC;COSMIC	7.780	Loss
AGC_Akt_AKT1_ST	Q7Z5H3	ARHGAP22	P31749	AKT1	S636	L631P	631	Missense	distal	-5	no	8.147	8.264	EPSD	ICGC;COSMIC	7.780	Up-regulation
AGC_Akt_AKT1_ST	Q7Z5H3	ARHGAP22	P31749	AKT1	S636	R637Q	637	Missense	proximal	1	no	8.147	7.853	EPSD	ICGC;COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	Q7Z5H3	ARHGAP22	P31749	AKT1	S636	D630E	630	Missense	distal	-6	no	8.147	8.220	EPSD	ICGC;COSMIC	7.780	Up-regulation
TK_Src_SrcB_LYN_Y	Q9GZY6	LAT2	P07948	LYN	Y95	F98S	98	Missense	distal	3	no	3.819	2.986	EPSD;PhosphoSitePlus	ICGC;COSMIC	1.526	Down-regulation
TK_Src_SrcB_LYN_Y	Q9GZY6	LAT2	P07948	LYN	Y95	Q96K	96	Missense	proximal	1	no	3.819	3.951	EPSD;PhosphoSitePlus	ICGC;COSMIC	1.526	Up-regulation
TK_Src_SrcB_LYN_Y	Q9GZY6	LAT2	P07948	LYN	Y110	S106P	106	Missense	distal	-4	no	3.541	2.244	EPSD;PhosphoSitePlus	ICGC;COSMIC	1.526	Down-regulation
TK_Src_SrcB_LYN_Y	Q9GZY6	LAT2	P07948	LYN	Y110	A115S	115	Missense	distal	5	no	3.541	3.227	EPSD;PhosphoSitePlus	ICGC	1.526	Down-regulation
TK_Src_SrcB_LYN_Y	Q9GZY6	LAT2	P07948	LYN	Y136	E137K	137	Missense	proximal	1	no	3.254	2.267	EPSD;PhosphoSitePlus	ICGC;COSMIC	1.526	Down-regulation
TK_Src_SrcB_LYN_Y	Q9GZY6	LAT2	P07948	LYN	Y136	D130H	130	Missense	distal	-6	no	3.254	3.440	EPSD;PhosphoSitePlus	ICGC;COSMIC	1.526	Up-regulation
TK_Src_SrcB_LYN_Y	Q9GZY6	LAT2	P07948	LYN	Y136	E129Q	129	Missense	distal	-7	no	3.254	2.908	EPSD;PhosphoSitePlus	ICGC;COSMIC	1.526	Down-regulation
TK_Src_SrcB_LYN_Y	P30419	NMT1	P07948	LYN	Y117	R115Q	115	Missense	proximal	-2	no	2.734	1.913	EPSD	ICGC;COSMIC	1.526	Down-regulation
TK_Src_SrcB_LYN_Y	P30419	NMT1	P07948	LYN	Y117	Q123H	123	Missense	distal	6	no	2.734	2.714	EPSD	ICGC;COSMIC	1.526	Down-regulation
TK_Src_SrcB_LYN_Y	P30419	NMT1	P07948	LYN	Y327	E331A	331	Missense	distal	4	no	2.046	1.894	EPSD	ICGC	1.526	Down-regulation
TK_Src_SrcB_LYN_Y	P30419	NMT1	P07948	LYN	Y327	E331D	331	Missense	distal	4	no	2.046	1.893	EPSD	ICGC;COSMIC	1.526	Down-regulation
TK_Src_SrcB_LYN_Y	P30419	NMT1	P07948	LYN	Y327	K334N	334	Missense	distal	7	no	2.046	2.013	EPSD	ICGC	1.526	Down-regulation
TK_Src_SrcB_LYN_Y	P02730	SLC4A1	P07948	LYN	Y21	Q18H	18	Missense	distal	-3	no	3.161	3.447	EPSD;PhosphoSitePlus	ICGC;COSMIC	1.526	Up-regulation
TK_Src_SrcB_LYN_Y	P02730	SLC4A1	P07948	LYN	Y21	P27L	27	Missense	distal	6	no	3.161	2.832	EPSD;PhosphoSitePlus	ICGC;COSMIC	1.526	Down-regulation
TK_Src_SrcB_LYN_Y	P00519	ABL1	P07948	LYN	Y70	F72V	72	Missense	proximal	2	no	3.222	2.887	EPSD;PhosphoSitePlus	ICGC;COSMIC	1.526	Down-regulation
TK_Src_SrcB_LYN_Y	P00519	ABL1	P07948	LYN	Y70	D71N	71	Missense	proximal	1	no	3.222	3.233	EPSD;PhosphoSitePlus	ICGC;COSMIC	1.526	Up-regulation
TK_Src_SrcB_LYN_Y	P00519	ABL1	P07948	LYN	Y70	Y70H	70	Missense	central	0	yes	3.222	0.000	EPSD;PhosphoSitePlus	ICGC;COSMIC	1.526	Loss
TK_Src_SrcB_LYN_Y	P00519	ABL1	P07948	LYN	Y70	S75R	75	Missense	distal	5	no	3.222	3.898	EPSD;PhosphoSitePlus	ICGC;COSMIC	1.526	Up-regulation
TK_Src_SrcB_LYN_Y	P00519	ABL1	P07948	LYN	Y70	V67F	67	Missense	distal	-3	no	3.222	1.718	EPSD;PhosphoSitePlus	ICGC;COSMIC	1.526	Down-regulation
TK_Src_SrcB_LYN_Y	P00519	ABL1	P07948	LYN	Y115	V111L	111	Missense	distal	-4	no	4.726	4.645	EPSD;PhosphoSitePlus	ICGC;COSMIC	1.526	Down-regulation
TK_Src_SrcB_LYN_Y	P00519	ABL1	P07948	LYN	Y115	V119F	119	Missense	distal	4	no	4.726	4.653	EPSD;PhosphoSitePlus	ICGC	1.526	Down-regulation
TK_Src_SrcB_LYN_Y	P00519	ABL1	P07948	LYN	Y128	R134L	134	Missense	distal	6	no	3.089	2.926	EPSD;PhosphoSitePlus	ICGC;COSMIC	1.526	Down-regulation
TK_Src_SrcB_LYN_Y	P00519	ABL1	P07948	LYN	Y128	P131S	131	Missense	distal	3	no	3.089	0.746	EPSD;PhosphoSitePlus	ICGC;GDSC	1.526	Loss
TK_Src_SrcB_LYN_Y	P00519	ABL1	P07948	LYN	Y139	G144W	144	Missense	distal	5	no	5.477	5.904	EPSD;PhosphoSitePlus	ICGC	1.526	Up-regulation
TK_Src_SrcB_LYN_Y	P00519	ABL1	P07948	LYN	Y139	R134L	134	Missense	distal	-5	no	5.477	4.258	EPSD;PhosphoSitePlus	ICGC;COSMIC	1.526	Down-regulation
TK_Src_SrcB_LYN_Y	P00519	ABL1	P07948	LYN	Y139	G144R	144	Missense	distal	5	no	5.477	4.743	EPSD;PhosphoSitePlus	ICGC	1.526	Down-regulation
TK_Src_SrcB_LYN_Y	P00519	ABL1	P07948	LYN	Y172	G169W	169	Missense	distal	-3	no	5.321	4.180	EPSD;PhosphoSitePlus	ICGC;COSMIC	1.526	Down-regulation
TK_Src_SrcB_LYN_Y	P00519	ABL1	P07948	LYN	Y172	R170G	170	Missense	proximal	-2	no	5.321	4.823	EPSD;PhosphoSitePlus	ICGC;COSMIC	1.526	Down-regulation
TK_Src_SrcB_LYN_Y	P00519	ABL1	P07948	LYN	Y185	E189G	189	Missense	distal	4	no	2.945	2.812	EPSD;PhosphoSitePlus	ICGC;COSMIC	1.526	Down-regulation
TK_Src_SrcB_LYN_Y	P00519	ABL1	P07948	LYN	Y185	V186I	186	Missense	proximal	1	no	2.945	2.151	EPSD;PhosphoSitePlus	ICGC;COSMIC	1.526	Down-regulation
TK_Src_SrcB_LYN_Y	P00519	ABL1	P07948	LYN	Y215	P216L	216	Missense	proximal	1	no	1.584	1.423	EPSD;PhosphoSitePlus	ICGC	1.526	Loss
TK_Src_SrcB_LYN_Y	P00519	ABL1	P07948	LYN	Y226	Y232C	232	Missense	distal	6	no	3.025	2.817	EPSD;PhosphoSitePlus	ICGC;COSMIC	1.526	Down-regulation
TK_Src_SrcB_LYN_Y	P00519	ABL1	P07948	LYN	Y226	D233N	233	Missense	distal	7	no	3.025	3.045	EPSD;PhosphoSitePlus	ICGC;COSMIC	1.526	Up-regulation
TK_Src_SrcB_LYN_Y	P00519	ABL1	P07948	LYN	Y226	D233Y	233	Missense	distal	7	no	3.025	3.012	EPSD;PhosphoSitePlus	ICGC	1.526	Down-regulation
TK_Src_SrcB_LYN_Y	P00519	ABL1	P07948	LYN	Y232	R239C	239	Missense	distal	7	no	2.013	2.111	EPSD	ICGC;COSMIC	1.526	Up-regulation
TK_Src_SrcB_LYN_Y	P00519	ABL1	P07948	LYN	Y232	Y232C	232	Missense	central	0	yes	2.013	0.000	EPSD	ICGC;COSMIC	1.526	Loss
TK_Src_SrcB_LYN_Y	P00519	ABL1	P07948	LYN	Y232	D233N	233	Missense	proximal	1	no	2.013	2.023	EPSD	ICGC;COSMIC	1.526	Up-regulation
TK_Src_SrcB_LYN_Y	P00519	ABL1	P07948	LYN	Y232	D233Y	233	Missense	proximal	1	no	2.013	2.448	EPSD	ICGC	1.526	Up-regulation
TK_Src_SrcB_LYN_Y	P00519	ABL1	P07948	LYN	Y232	R239H	239	Missense	distal	7	no	2.013	2.063	EPSD	ICGC	1.526	Up-regulation
TK_Src_SrcB_LYN_Y	P00519	ABL1	P07948	LYN	Y1064	G1060S	1060	Missense	distal	-4	no	2.096	2.753	EPSD	ICGC;COSMIC	1.526	Up-regulation
TK_Src_SrcB_LYN_Y	P00519	ABL1	P07948	LYN	Y1064	G1060C	1060	Missense	distal	-4	no	2.096	-0.089	EPSD	ICGC;COSMIC	1.526	Loss
TK_Src_SrcB_LYN_Y	P00519	ABL1	P07948	LYN	Y1064	V1071L	1071	Missense	distal	7	no	2.096	2.128	EPSD	ICGC	1.526	Up-regulation
TK_Src_SrcB_LYN_Y	P25490	YY1	P07948	LYN	Y145	I146V	146	Missense	proximal	1	no	1.370	2.163	EPSD	ICGC;COSMIC	1.526	Gain
TK_Src_SrcB_LYN_Y	P25490	YY1	P07948	LYN	Y254	P248H	248	Missense	distal	-6	no	2.433	2.519	EPSD;PhosphoSitePlus	ICGC;COSMIC	1.526	Up-regulation
TK_Src_SrcB_LYN_Y	P25490	YY1	P07948	LYN	Y383	C390F	390	Missense	distal	7	no	3.286	3.175	EPSD;PhosphoSitePlus	ICGC	1.526	Down-regulation
TK_Src_SrcB_LYN_Y	O43823	AKAP8	P07948	LYN	Y80	H76N	76	Missense	distal	-4	no	1.900	2.712	EPSD;PhosphoSitePlus	ICGC	1.526	Up-regulation
TK_Src_SrcB_LYN_Y	O43823	AKAP8	P07948	LYN	Y146	N144D	144	Missense	proximal	-2	no	4.024	4.091	EPSD;PhosphoSitePlus	ICGC;COSMIC	1.526	Up-regulation
TK_Src_SrcB_LYN_Y	O43823	AKAP8	P07948	LYN	Y146	H143N	143	Missense	distal	-3	no	4.024	3.721	EPSD;PhosphoSitePlus	ICGC	1.526	Down-regulation
TK_Src_SrcB_LYN_Y	O43823	AKAP8	P07948	LYN	Y146	P148H	148	Missense	proximal	2	no	4.024	3.927	EPSD;PhosphoSitePlus	ICGC;COSMIC	1.526	Down-regulation
TK_Src_SrcB_LYN_Y	O43823	AKAP8	P07948	LYN	Y146	R147H	147	Missense	proximal	1	no	4.024	4.474	EPSD;PhosphoSitePlus	ICGC;COSMIC;CCLE	1.526	Up-regulation
TK_Src_SrcB_LYN_Y	O43823	AKAP8	P07948	LYN	Y150	N144D	144	Missense	distal	-6	no	2.172	2.146	EPSD;PhosphoSitePlus	ICGC;COSMIC	1.526	Down-regulation
TK_Src_SrcB_LYN_Y	O43823	AKAP8	P07948	LYN	Y150	D157E	157	Missense	distal	7	no	2.172	2.183	EPSD;PhosphoSitePlus	ICGC	1.526	Up-regulation
TK_Src_SrcB_LYN_Y	O43823	AKAP8	P07948	LYN	Y150	H143N	143	Missense	distal	-7	no	2.172	2.023	EPSD;PhosphoSitePlus	ICGC	1.526	Down-regulation
TK_Src_SrcB_LYN_Y	O43823	AKAP8	P07948	LYN	Y150	P148H	148	Missense	proximal	-2	no	2.172	2.086	EPSD;PhosphoSitePlus	ICGC;COSMIC	1.526	Down-regulation
TK_Src_SrcB_LYN_Y	O43823	AKAP8	P07948	LYN	Y150	R147H	147	Missense	distal	-3	no	2.172	3.198	EPSD;PhosphoSitePlus	ICGC;COSMIC;CCLE	1.526	Up-regulation
TK_Src_SrcB_LYN_Y	O43823	AKAP8	P07948	LYN	Y154	D157E	157	Missense	distal	3	no	2.317	3.463	EPSD;PhosphoSitePlus	ICGC	1.526	Up-regulation
TK_Src_SrcB_LYN_Y	O43823	AKAP8	P07948	LYN	Y154	P148H	148	Missense	distal	-6	no	2.317	2.403	EPSD;PhosphoSitePlus	ICGC;COSMIC	1.526	Up-regulation
TK_Src_SrcB_LYN_Y	O43823	AKAP8	P07948	LYN	Y154	R147H	147	Missense	distal	-7	no	2.317	2.568	EPSD;PhosphoSitePlus	ICGC;COSMIC;CCLE	1.526	Up-regulation
TK_Src_SrcB_LYN_Y	O43823	AKAP8	P07948	LYN	Y170	P176L	176	Missense	distal	6	no	1.993	1.664	EPSD;PhosphoSitePlus	ICGC;COSMIC	1.526	Down-regulation
TK_Src_SrcB_LYN_Y	O43823	AKAP8	P07948	LYN	Y229	E226K	226	Missense	distal	-3	no	2.645	2.127	EPSD	ICGC;COSMIC	1.526	Down-regulation
TK_Src_SrcB_LYN_Y	O43823	AKAP8	P07948	LYN	Y229	G232E	232	Missense	distal	3	no	2.645	4.485	EPSD	ICGC	1.526	Up-regulation
TK_Src_SrcB_LYN_Y	P11274	BCR	P07948	LYN	Y177	F182L	182	Missense	distal	5	no	5.347	6.026	PhosphoSitePlus	ICGC;COSMIC	1.526	Up-regulation
TK_Src_SrcB_LYN_Y	P11274	BCR	P07948	LYN	Y279	Y276H	276	Missense	distal	-3	no	2.613	2.924	EPSD	ICGC;COSMIC	1.526	Up-regulation
TK_Src_SrcB_LYN_Y	P11274	BCR	P07948	LYN	Y279	L274M	274	Missense	distal	-5	no	2.613	3.109	EPSD	ICGC;COSMIC	1.526	Up-regulation
TK_Src_SrcB_LYN_Y	P11274	BCR	P07948	LYN	Y279	G285W	285	Missense	distal	6	no	2.613	2.737	EPSD	ICGC;COSMIC	1.526	Up-regulation
TK_Src_SrcB_LYN_Y	P11274	BCR	P07948	LYN	Y283	Y276H	276	Missense	distal	-7	no	2.669	2.869	EPSD	ICGC;COSMIC	1.526	Up-regulation
TK_Src_SrcB_LYN_Y	P11274	BCR	P07948	LYN	Y283	G285W	285	Missense	proximal	2	no	2.669	2.188	EPSD	ICGC;COSMIC	1.526	Down-regulation
TK_Src_SrcB_LYN_Y	P11274	BCR	P07948	LYN	Y360	P355T	355	Missense	distal	-5	no	2.787	3.259	EPSD	ICGC;COSMIC	1.526	Up-regulation
TK_Src_SrcB_LYN_Y	P11274	BCR	P07948	LYN	Y360	S367G	367	Missense	distal	7	no	2.787	2.886	EPSD	ICGC;COSMIC	1.526	Up-regulation
TK_Src_SrcB_LYN_Y	P11274	BCR	P07948	LYN	Y360	R364L	364	Missense	distal	4	no	2.787	2.612	EPSD	ICGC;COSMIC	1.526	Down-regulation
TK_Src_SrcB_LYN_Y	P11274	BCR	P07948	LYN	Y360	R361S	361	Missense	proximal	1	no	2.787	3.092	EPSD	ICGC;COSMIC	1.526	Up-regulation
TK_Src_SrcB_LYN_Y	P11274	BCR	P07948	LYN	Y561	G563V	563	Missense	proximal	2	no	2.514	2.485	EPSD	ICGC	1.526	Down-regulation
TK_Src_SrcB_LYN_Y	P11274	BCR	P07948	LYN	Y852	L847M	847	Missense	distal	-5	no	1.173	1.669	EPSD	ICGC;COSMIC	1.526	Gain
TK_Src_SrcB_LYN_Y	P11274	BCR	P07948	LYN	Y910	V917I	917	Missense	distal	7	no	2.129	2.151	EPSD	ICGC;COSMIC	1.526	Up-regulation
TK_Src_SrcB_LYN_Y	P11274	BCR	P07948	LYN	Y910	V915G	915	Missense	distal	5	no	2.129	3.648	EPSD	ICGC;COSMIC	1.526	Up-regulation
TK_Src_SrcB_LYN_Y	P11274	BCR	P07948	LYN	Y910	Y910C	910	Missense	central	0	yes	2.129	0.000	EPSD	ICGC;COSMIC	1.526	Loss
TK_Src_SrcB_LYN_Y	P11274	BCR	P07948	LYN	Y910	G911V	911	Missense	proximal	1	no	2.129	2.696	EPSD	ICGC	1.526	Up-regulation
TK_Src_SrcB_LYN_Y	O15492	RGS16	P07948	LYN	Y168	R170C	170	Missense	proximal	2	no	3.923	3.154	EPSD;PhosphoSitePlus	ICGC;COSMIC;CCLE	1.526	Down-regulation
TK_Src_SrcB_LYN_Y	O15492	RGS16	P07948	LYN	Y168	E164K	164	Missense	distal	-4	no	3.923	3.550	EPSD;PhosphoSitePlus	ICGC	1.526	Down-regulation
TK_Src_SrcB_LYN_Y	O15492	RGS16	P07948	LYN	Y177	R170C	170	Missense	distal	-7	no	2.350	1.979	PhosphoSitePlus;EPSD	ICGC;COSMIC;CCLE	1.526	Down-regulation
TK_Src_SrcB_LYN_Y	O15492	RGS16	P07948	LYN	Y177	R178Q	178	Missense	proximal	1	no	2.350	2.049	PhosphoSitePlus;EPSD	ICGC;COSMIC	1.526	Down-regulation
TK_Src_SrcB_LYN_Y	O15492	RGS16	P07948	LYN	Y177	D179E	179	Missense	proximal	2	no	2.350	2.588	PhosphoSitePlus;EPSD	ICGC	1.526	Up-regulation
TK_Src_SrcB_LYN_Y	Q06187	BTK	P07948	LYN	Y223	M228I	228	Missense	distal	5	no	2.734	3.210	PhosphoSitePlus;EPSD	ICGC;COSMIC	1.526	Up-regulation
TK_Src_SrcB_LYN_Y	Q06187	BTK	P07948	LYN	Y223	A221D	221	Missense	proximal	-2	no	2.734	3.140	PhosphoSitePlus;EPSD	ICGC	1.526	Up-regulation
TK_Src_SrcB_LYN_Y	Q06187	BTK	P07948	LYN	Y223	M228T	228	Missense	distal	5	no	2.734	2.922	PhosphoSitePlus;EPSD	ICGC;COSMIC	1.526	Up-regulation
TK_Src_SrcB_LYN_Y	Q06187	BTK	P07948	LYN	Y551	K558T	558	Missense	distal	7	no	6.089	6.012	EPSD;PhosphoSitePlus	ICGC	1.526	Down-regulation
TK_Src_SrcB_LYN_Y	P12318	FCGR2A	P07948	LYN	Y281	L274P	274	Missense	distal	-7	no	4.134	4.381	EPSD	ICGC;COSMIC	1.526	Up-regulation
TK_Src_SrcB_LYN_Y	P12318	FCGR2A	P07948	LYN	Y281	Y288F	288	Missense	distal	7	no	4.134	4.151	EPSD	ICGC;COSMIC	1.526	Up-regulation
TK_Src_SrcB_LYN_Y	P12318	FCGR2A	P07948	LYN	Y288	Y288F	288	Missense	central	0	yes	2.252	0.000	EPSD	ICGC;COSMIC	1.526	Loss
TK_Src_SrcB_LYN_Y	P12318	FCGR2A	P07948	LYN	Y288	P293H	293	Missense	distal	5	no	2.252	1.772	EPSD	ICGC;COSMIC	1.526	Down-regulation
TK_Src_SrcB_LYN_Y	P32927	CSF2RB	P07948	LYN	Y468	G467W	467	Missense	proximal	-1	no	0.824	1.578	EPSD;PhosphoSitePlus	ICGC;COSMIC	1.526	Gain
TK_Src_SrcB_LYN_Y	P15391	CD19	P07948	LYN	Y348	G343W	343	Missense	distal	-5	no	2.608	2.982	EPSD	ICGC;COSMIC	1.526	Up-regulation
TK_Src_SrcB_LYN_Y	P15391	CD19	P07948	LYN	Y378	P376T	376	Missense	proximal	-2	no	3.346	3.379	EPSD	ICGC;COSMIC	1.526	Up-regulation
TK_Src_SrcB_LYN_Y	P15391	CD19	P07948	LYN	Y439	G438C	438	Missense	proximal	-1	no	2.774	1.848	EPSD	ICGC	1.526	Down-regulation
TK_Src_SrcB_LYN_Y	P15391	CD19	P07948	LYN	Y500	S497Y	497	Missense	distal	-3	no	2.374	2.496	EPSD;PhosphoSitePlus	ICGC;COSMIC	1.526	Up-regulation
TK_Src_SrcB_LYN_Y	P15391	CD19	P07948	LYN	Y500	L507M	507	Missense	distal	7	no	2.374	2.294	EPSD;PhosphoSitePlus	ICGC	1.526	Down-regulation
TK_Src_SrcB_LYN_Y	P15391	CD19	P07948	LYN	Y500	S499T	499	Missense	proximal	-1	no	2.374	4.428	EPSD;PhosphoSitePlus	ICGC	1.526	Up-regulation
TK_Src_SrcB_LYN_Y	P15391	CD19	P07948	LYN	Y500	Q498H	498	Missense	proximal	-2	no	2.374	2.959	EPSD;PhosphoSitePlus	ICGC	1.526	Up-regulation
TK_Src_SrcB_LYN_Y	P15391	CD19	P07948	LYN	Y531	E525K	525	Missense	distal	-6	no	6.658	6.226	PhosphoSitePlus;EPSD	ICGC;COSMIC	1.526	Down-regulation
TK_Src_SrcB_LYN_Y	P15391	CD19	P07948	LYN	Y531	A528T	528	Missense	distal	-3	no	6.658	8.593	PhosphoSitePlus;EPSD	ICGC;COSMIC	1.526	Up-regulation
TK_Src_SrcB_LYN_Y	Q13568	IRF5	P07948	LYN	Y136	Q131H	131	Missense	distal	-5	no	1.247	1.654	EPSD	ICGC	1.526	Gain
TK_Src_SrcB_LYN_Y	Q13568	IRF5	P07948	LYN	Y136	G139C	139	Missense	distal	3	no	1.247	2.869	EPSD	ICGC;COSMIC	1.526	Gain
TK_Src_SrcB_LYN_Y	Q13568	IRF5	P07948	LYN	Y313	P306H	306	Missense	distal	-7	no	2.300	2.451	PhosphoSitePlus;EPSD	ICGC;COSMIC	1.526	Up-regulation
TK_Src_SrcB_LYN_Y	Q13568	IRF5	P07948	LYN	Y313	R311H	311	Missense	proximal	-2	no	2.300	2.065	PhosphoSitePlus;EPSD	ICGC;COSMIC	1.526	Down-regulation
TK_Src_SrcB_LYN_Y	Q13568	IRF5	P07948	LYN	Y335	R338C	338	Missense	distal	3	no	5.361	5.777	EPSD;PhosphoSitePlus	ICGC;COSMIC	1.526	Up-regulation
TK_Src_SrcB_LYN_Y	Q13568	IRF5	P07948	LYN	Y335	C342R	342	Missense	distal	7	no	5.361	5.263	EPSD;PhosphoSitePlus	ICGC;COSMIC	1.526	Down-regulation
TK_Src_SrcB_LYN_Y	P07948	LYN	P07948	LYN	Y397	T398K	398	Missense	proximal	1	no	8.295	7.553	PhosphoSitePlus;EPSD	ICGC;COSMIC	1.526	Down-regulation
TK_Src_SrcB_LYN_Y	P07948	LYN	P07948	LYN	Y397	R400M	400	Missense	distal	3	no	8.295	9.071	PhosphoSitePlus;EPSD	ICGC;COSMIC	1.526	Up-regulation
TK_Src_SrcB_LYN_Y	Q13263	TRIM28	P07948	LYN	Y517	R524C	524	Missense	distal	7	no	3.224	3.322	PhosphoSitePlus;EPSD	ICGC;COSMIC	1.526	Up-regulation
TK_Src_SrcB_LYN_Y	Q13263	TRIM28	P07948	LYN	Y517	D516E	516	Missense	proximal	-1	no	3.224	3.581	PhosphoSitePlus;EPSD	ICGC	1.526	Up-regulation
TK_Src_SrcB_LYN_Y	Q14790	CASP8	P07948	LYN	Y448	D455A	455	Missense	distal	7	no	3.836	3.841	EPSD;PhosphoSitePlus	ICGC	1.526	Up-regulation
TK_Src_SrcB_LYN_Y	P46527	CDKN1B	P07948	LYN	Y74	V79L	79	Missense	distal	5	no	1.475	2.639	EPSD	ICGC;COSMIC	1.526	Gain
TK_Src_SrcB_LYN_Y	P46527	CDKN1B	P07948	LYN	Y88	Y89H	89	Missense	proximal	1	no	4.687	5.055	PhosphoSitePlus	ICGC;COSMIC	1.526	Up-regulation
TK_Src_SrcB_LYN_Y	P60484	PTEN	P07948	LYN	Y27	G20A	20	Missense	distal	-7	no	1.661	1.672	EPSD	ICGC;COSMIC	1.526	Up-regulation
TK_Src_SrcB_LYN_Y	P60484	PTEN	P07948	LYN	Y27	I32S	32	Missense	distal	5	no	1.661	0.650	EPSD	ICGC;COSMIC	1.526	Loss
TK_Src_SrcB_LYN_Y	P60484	PTEN	P07948	LYN	Y27	Y27N	27	Missense	central	0	yes	1.661	0.000	EPSD	ICGC;COSMIC	1.526	Loss
TK_Src_SrcB_LYN_Y	P60484	PTEN	P07948	LYN	Y27	I33T	33	Missense	distal	6	no	1.661	1.782	EPSD	ICGC;COSMIC	1.526	Up-regulation
TK_Src_SrcB_LYN_Y	P60484	PTEN	P07948	LYN	Y27	I33S	33	Missense	distal	6	no	1.661	1.773	EPSD	ICGC;COSMIC	1.526	Up-regulation
TK_Src_SrcB_LYN_Y	P60484	PTEN	P07948	LYN	Y27	N31K	31	Missense	distal	4	no	1.661	1.553	EPSD	ICGC;COSMIC	1.526	Down-regulation
TK_Src_SrcB_LYN_Y	P60484	PTEN	P07948	LYN	Y27	I28N	28	Missense	proximal	1	no	1.661	1.590	EPSD	ICGC;COSMIC	1.526	Down-regulation
TK_Src_SrcB_LYN_Y	P60484	PTEN	P07948	LYN	Y46	V45E	45	Missense	proximal	-1	no	2.264	3.326	EPSD	ICGC;COSMIC	1.526	Up-regulation
TK_Src_SrcB_LYN_Y	P60484	PTEN	P07948	LYN	Y46	G44C	44	Missense	proximal	-2	no	2.264	-1.968	EPSD	ICGC	1.526	Loss
TK_Src_SrcB_LYN_Y	P60484	PTEN	P07948	LYN	Y46	Y46D	46	Missense	central	0	yes	2.264	0.000	EPSD	ICGC;COSMIC	1.526	Loss
TK_Src_SrcB_LYN_Y	P60484	PTEN	P07948	LYN	Y46	N49K	49	Missense	distal	3	no	2.264	1.388	EPSD	ICGC	1.526	Loss
TK_Src_SrcB_LYN_Y	P60484	PTEN	P07948	LYN	Y46	L42P	42	Missense	distal	-4	no	2.264	1.752	EPSD	ICGC;COSMIC	1.526	Down-regulation
TK_Src_SrcB_LYN_Y	P60484	PTEN	P07948	LYN	Y178	Y177C	177	Missense	proximal	-1	no	4.329	2.719	EPSD	ICGC;COSMIC	1.526	Down-regulation
TK_Src_SrcB_LYN_Y	P60484	PTEN	P07948	LYN	Y178	Y177S	177	Missense	proximal	-1	no	4.329	3.618	EPSD	ICGC;COSMIC	1.526	Down-regulation
TK_Src_SrcB_LYN_Y	P60484	PTEN	P07948	LYN	Y178	Y178S	178	Missense	central	0	yes	4.329	0.000	EPSD	ICGC;COSMIC	1.526	Loss
TK_Src_SrcB_LYN_Y	P60484	PTEN	P07948	LYN	Y178	V175L	175	Missense	distal	-3	no	4.329	2.498	EPSD	ICGC;COSMIC	1.526	Down-regulation
TK_Src_SrcB_LYN_Y	P60484	PTEN	P07948	LYN	Y178	H185D	185	Missense	distal	7	no	4.329	4.263	EPSD	ICGC;COSMIC	1.526	Down-regulation
TK_Src_SrcB_LYN_Y	P60484	PTEN	P07948	LYN	Y315	D312Y	312	Missense	distal	-3	no	3.455	3.408	EPSD	ICGC	1.526	Down-regulation
TK_Src_SrcB_LYN_Y	P22681	CBL	P07948	LYN	Y141	G136V	136	Missense	distal	-5	no	2.213	2.779	EPSD	ICGC	1.526	Up-regulation
TK_Src_SrcB_LYN_Y	P22681	CBL	P07948	LYN	Y371	Y371H	371	Missense	central	0	yes	2.726	0.000	PhosphoSitePlus	ICGC;COSMIC	1.526	Loss
TK_Src_SrcB_LYN_Y	P22681	CBL	P07948	LYN	Y371	E366K	366	Missense	distal	-5	no	2.726	1.900	PhosphoSitePlus	ICGC;COSMIC	1.526	Down-regulation
TK_Src_SrcB_LYN_Y	P22681	CBL	P07948	LYN	Y371	Y368C	368	Missense	distal	-3	no	2.726	1.394	PhosphoSitePlus	ICGC;COSMIC	1.526	Loss
TK_Src_SrcB_LYN_Y	P22681	CBL	P07948	LYN	Y774	G773E	773	Missense	proximal	-1	no	2.517	4.342	EPSD	ICGC	1.526	Up-regulation
TK_Src_SrcB_LYN_Y	P14317	HCLS1	P07948	LYN	Y83	R86L	86	Missense	distal	3	no	1.814	2.604	EPSD	ICGC;COSMIC	1.526	Up-regulation
TK_Src_SrcB_LYN_Y	P14317	HCLS1	P07948	LYN	Y190	H184N	184	Missense	distal	-6	no	2.670	2.510	EPSD	ICGC;COSMIC	1.526	Down-regulation
TK_Src_SrcB_LYN_Y	P14317	HCLS1	P07948	LYN	Y190	A191D	191	Missense	proximal	1	no	2.670	3.063	EPSD	ICGC	1.526	Up-regulation
TK_Src_SrcB_LYN_Y	P14317	HCLS1	P07948	LYN	Y190	H184Q	184	Missense	distal	-6	no	2.670	2.517	EPSD	ICGC;COSMIC	1.526	Down-regulation
TK_Src_SrcB_LYN_Y	P14317	HCLS1	P07948	LYN	Y190	Q187K	187	Missense	distal	-3	no	2.670	3.099	EPSD	ICGC;COSMIC	1.526	Up-regulation
TK_Src_SrcB_LYN_Y	P14317	HCLS1	P07948	LYN	Y190	K192N	192	Missense	proximal	2	no	2.670	2.812	EPSD	ICGC;COSMIC;GDSC;CCLE	1.526	Up-regulation
TK_Src_SrcB_LYN_Y	P14317	HCLS1	P07948	LYN	Y222	I228M	228	Missense	distal	6	no	5.208	5.424	PhosphoSitePlus	ICGC;COSMIC	1.526	Up-regulation
TK_Src_SrcB_LYN_Y	P14317	HCLS1	P07948	LYN	Y222	T225M	225	Missense	distal	3	no	5.208	6.200	PhosphoSitePlus	ICGC;COSMIC	1.526	Up-regulation
TK_Src_SrcB_LYN_Y	P14317	HCLS1	P07948	LYN	Y222	T225K	225	Missense	distal	3	no	5.208	4.756	PhosphoSitePlus	ICGC	1.526	Down-regulation
TK_Src_SrcB_LYN_Y	P14317	HCLS1	P07948	LYN	Y360	E361K	361	Missense	proximal	1	no	1.772	0.785	EPSD	ICGC;COSMIC	1.526	Loss
TK_Src_SrcB_LYN_Y	P14317	HCLS1	P07948	LYN	Y397	P403T	403	Missense	distal	6	no	4.274	4.005	EPSD	ICGC	1.526	Down-regulation
TK_Src_SrcB_LYN_Y	Q8N6F7	GCSAM	P07948	LYN	Y80	D74N	74	Missense	distal	-6	no	2.509	2.535	EPSD	ICGC;COSMIC	1.526	Up-regulation
TK_Src_SrcB_LYN_Y	Q8N6F7	GCSAM	P07948	LYN	Y80	E82D	82	Missense	proximal	2	no	2.509	2.272	EPSD	ICGC;COSMIC	1.526	Down-regulation
TK_Src_SrcB_LYN_Y	Q8N6F7	GCSAM	P07948	LYN	Y80	T87I	87	Missense	distal	7	no	2.509	2.582	EPSD	ICGC;COSMIC	1.526	Up-regulation
TK_Src_SrcB_LYN_Y	Q8N6F7	GCSAM	P07948	LYN	Y107	E108D	108	Missense	proximal	1	no	4.450	3.279	EPSD;PhosphoSitePlus	ICGC;COSMIC	1.526	Down-regulation
TK_Src_SrcB_LYN_Y	Q8N6F7	GCSAM	P07948	LYN	Y107	P111S	111	Missense	distal	4	no	4.450	4.265	EPSD;PhosphoSitePlus	ICGC	1.526	Down-regulation
TK_Src_SrcB_LYN_Y	Q8N6F7	GCSAM	P07948	LYN	Y107	A114V	114	Missense	distal	7	no	4.450	4.471	EPSD;PhosphoSitePlus	ICGC	1.526	Up-regulation
TK_Src_SrcB_LYN_Y	Q8N6F7	GCSAM	P07948	LYN	Y128	G123E	123	Missense	distal	-5	no	3.885	4.788	PhosphoSitePlus;EPSD	ICGC;COSMIC;GDSC	1.526	Up-regulation
TK_Src_SrcB_LYN_Y	Q8N6F7	GCSAM	P07948	LYN	Y128	G123R	123	Missense	distal	-5	no	3.885	4.700	PhosphoSitePlus;EPSD	ICGC;COSMIC	1.526	Up-regulation
TK_Src_SrcB_LYN_Y	Q9H792	PEAK1	P07948	LYN	Y616	H611Y	611	Missense	distal	-5	no	2.500	1.637	EPSD	ICGC	1.526	Down-regulation
TK_Src_SrcB_LYN_Y	Q9H792	PEAK1	P07948	LYN	Y635	I630S	630	Missense	distal	-5	no	1.480	1.553	PhosphoSitePlus	ICGC	1.526	Gain
TK_Src_SrcB_LYN_Y	Q9H792	PEAK1	P07948	LYN	Y635	D636G	636	Missense	proximal	1	no	1.480	1.789	PhosphoSitePlus	ICGC	1.526	Gain
TK_Src_SrcB_LYN_Y	Q9H792	PEAK1	P07948	LYN	Y641	D636G	636	Missense	distal	-5	no	2.036	2.464	EPSD	ICGC	1.526	Up-regulation
TK_Src_SrcB_LYN_Y	Q9H792	PEAK1	P07948	LYN	Y641	L638I	638	Missense	distal	-3	no	2.036	2.794	EPSD	ICGC	1.526	Up-regulation
TK_Src_SrcB_LYN_Y	Q9H792	PEAK1	P07948	LYN	Y665	E669K	669	Missense	distal	4	no	3.100	3.004	EPSD	ICGC;COSMIC	1.526	Down-regulation
TK_Src_SrcB_LYN_Y	Q9H792	PEAK1	P07948	LYN	Y665	E669Q	669	Missense	distal	4	no	3.100	2.935	EPSD	ICGC;COSMIC	1.526	Down-regulation
TK_Src_SrcB_LYN_Y	Q9H792	PEAK1	P07948	LYN	Y880	L886F	886	Missense	distal	6	no	2.188	1.999	EPSD	ICGC	1.526	Down-regulation
TK_Src_SrcB_LYN_Y	Q9H792	PEAK1	P07948	LYN	Y880	R874H	874	Missense	distal	-6	no	2.188	2.562	EPSD	ICGC	1.526	Up-regulation
TK_Src_SrcB_LYN_Y	Q9H792	PEAK1	P07948	LYN	Y1587	A1584T	1584	Missense	distal	-3	no	-0.379	1.556	EPSD	ICGC	1.526	Gain
TK_Src_SrcB_LYN_Y	P11802	CDK4	P07948	LYN	Y17	G15C	15	Missense	proximal	-2	no	3.291	-0.941	PhosphoSitePlus	ICGC;COSMIC	1.526	Loss
TK_Src_SrcB_LYN_Y	P42768	WAS	P07948	LYN	Y54	A47S	47	Missense	distal	-7	no	2.706	2.608	EPSD	ICGC	1.526	Down-regulation
TK_Src_SrcB_LYN_Y	P42768	WAS	P07948	LYN	Y102	Y102H	102	Missense	central	0	yes	2.571	0.000	EPSD	ICGC;COSMIC	1.526	Loss
TK_Src_SrcB_LYN_Y	P42768	WAS	P07948	LYN	Y102	Q99H	99	Missense	distal	-3	no	2.571	2.857	EPSD	ICGC	1.526	Up-regulation
TK_Src_SrcB_LYN_Y	P42768	WAS	P07948	LYN	Y212	P218L	218	Missense	distal	6	no	3.424	3.095	EPSD	ICGC	1.526	Down-regulation
TK_Src_SrcB_LYN_Y	P42768	WAS	P07948	LYN	Y212	P205H	205	Missense	distal	-7	no	3.424	3.576	EPSD	ICGC;COSMIC	1.526	Up-regulation
TK_Src_SrcB_LYN_Y	P42768	WAS	P07948	LYN	Y212	P218S	218	Missense	distal	6	no	3.424	3.147	EPSD	ICGC;COSMIC	1.526	Down-regulation
TK_Src_SrcB_LYN_Y	P42768	WAS	P07948	LYN	Y291	D292Y	292	Missense	proximal	1	no	1.806	2.241	PhosphoSitePlus	ICGC;COSMIC	1.526	Up-regulation
TK_Src_SrcB_LYN_Y	P42768	WAS	P07948	LYN	Y291	A284S	284	Missense	distal	-7	no	1.806	1.708	PhosphoSitePlus	ICGC	1.526	Down-regulation
TK_Src_SrcB_LYN_Y	P42768	WAS	P07948	LYN	Y291	I290M	290	Missense	proximal	-1	no	1.806	1.560	PhosphoSitePlus	ICGC;COSMIC	1.526	Down-regulation
TK_Src_SrcB_LYN_Y	P42768	WAS	P07948	LYN	Y291	E285K	285	Missense	distal	-6	no	1.806	1.375	PhosphoSitePlus	ICGC;COSMIC	1.526	Loss
TK_Src_SrcB_LYN_Y	P33993	MCM7	P07948	LYN	Y126	R132C	132	Missense	distal	6	no	1.746	1.283	EPSD	ICGC;COSMIC	1.526	Loss
TK_Src_SrcB_LYN_Y	P33993	MCM7	P07948	LYN	Y126	P122T	122	Missense	distal	-4	no	1.746	3.325	EPSD	ICGC	1.526	Up-regulation
TK_Src_SrcB_LYN_Y	P33993	MCM7	P07948	LYN	Y126	Q125K	125	Missense	proximal	-1	no	1.746	2.056	EPSD	ICGC	1.526	Up-regulation
TK_Src_SrcB_LYN_Y	P33993	MCM7	P07948	LYN	Y600	L607M	607	Missense	distal	7	no	3.399	3.318	PhosphoSitePlus	ICGC	1.526	Down-regulation
TK_Src_SrcB_LYN_Y	Q9UN19	DAPP1	P07948	LYN	Y139	V142A	142	Missense	distal	3	no	8.133	6.998	PhosphoSitePlus	ICGC;COSMIC	1.526	Down-regulation
TK_Src_SrcB_LYN_Y	Q9UN19	DAPP1	P07948	LYN	Y139	I138V	138	Missense	proximal	-1	no	8.133	7.270	PhosphoSitePlus	ICGC;COSMIC	1.526	Down-regulation
TK_Src_SrcB_LYN_Y	P35354	PTGS2	P07948	LYN	Y120	N117K	117	Missense	distal	-3	no	2.017	2.464	PhosphoSitePlus	ICGC	1.526	Up-regulation
TK_Src_SrcB_LYN_Y	P35354	PTGS2	P07948	LYN	Y120	P113S	113	Missense	distal	-7	no	2.017	1.890	PhosphoSitePlus	ICGC	1.526	Down-regulation
TK_Src_SrcB_LYN_Y	P35354	PTGS2	P07948	LYN	Y120	A127P	127	Missense	distal	7	no	2.017	1.991	PhosphoSitePlus	ICGC	1.526	Down-regulation
TK_Src_SrcB_LYN_Y	P35354	PTGS2	P07948	LYN	Y120	W125C	125	Missense	distal	5	no	2.017	2.300	PhosphoSitePlus	ICGC;COSMIC	1.526	Up-regulation
TK_Src_SrcB_LYN_Y	P35354	PTGS2	P07948	LYN	Y248	T255A	255	Missense	distal	7	no	2.244	2.274	EPSD	ICGC	1.526	Up-regulation
TK_Src_SrcB_LYN_Y	P35354	PTGS2	P07948	LYN	Y248	K253R	253	Missense	distal	5	no	2.244	1.628	EPSD	ICGC;COSMIC	1.526	Down-regulation
TK_Src_SrcB_LYN_Y	Q12972	PPP1R8	P07948	LYN	Y264	G265K	265	Missense	proximal	1	no	4.182	4.057	EPSD	ICGC	1.526	Down-regulation
AGC_RSK_RSKp90_RPS6KA3_ST	Q14934	NFATC4	P51812	RPS6KA3	S73	R77H	77	Missense	distal	4	no	1.827	1.879	EPSD	ICGC;COSMIC	1.803	Up-regulation
AGC_RSK_RSKp90_RPS6KA3_ST	Q14934	NFATC4	P51812	RPS6KA3	S73	P74L	74	Missense	proximal	1	no	1.827	1.847	EPSD	ICGC;COSMIC	1.803	Up-regulation
AGC_RSK_RSKp90_RPS6KA3_ST	Q99683	MAP3K5	P51812	RPS6KA3	S115	S110R	110	Missense	distal	-5	no	1.528	1.845	EPSD	ICGC	1.803	Gain
AGC_RSK_RSKp90_RPS6KA3_ST	Q99683	MAP3K5	P51812	RPS6KA3	S613	E618D	618	Missense	distal	5	no	3.751	3.773	EPSD	ICGC;COSMIC	1.803	Up-regulation
AGC_RSK_RSKp90_RPS6KA3_ST	Q99683	MAP3K5	P51812	RPS6KA3	S719	P721H	721	Missense	proximal	2	no	2.810	2.787	EPSD	ICGC	1.803	Down-regulation
AGC_RSK_RSKp90_RPS6KA3_ST	Q99683	MAP3K5	P51812	RPS6KA3	S719	S716R	716	Missense	distal	-3	no	2.810	4.817	EPSD	ICGC	1.803	Up-regulation
AGC_RSK_RSKp90_RPS6KA3_ST	Q99683	MAP3K5	P51812	RPS6KA3	S719	S719Y	719	Missense	central	0	yes	2.810	0.000	EPSD	ICGC;COSMIC	1.803	Loss
AGC_RSK_RSKp90_RPS6KA3_ST	Q92934	BAD	P51812	RPS6KA3	S74	R72S	72	Missense	proximal	-2	no	1.804	1.389	EPSD	ICGC	1.803	Loss
AGC_RSK_RSKp90_RPS6KA3_ST	Q92934	BAD	P51812	RPS6KA3	S74	T80K	80	Missense	distal	6	no	1.804	1.842	EPSD	ICGC	1.803	Up-regulation
AGC_RSK_RSKp90_RPS6KA3_ST	Q92934	BAD	P51812	RPS6KA3	S74	S74G	74	Missense	central	0	yes	1.804	0.000	EPSD	ICGC;COSMIC	1.803	Loss
AGC_RSK_RSKp90_RPS6KA3_ST	Q92934	BAD	P51812	RPS6KA3	S75	R72S	72	Missense	distal	-3	no	4.372	2.364	PhosphoSitePlus;EPSD	ICGC	1.803	Down-regulation
AGC_RSK_RSKp90_RPS6KA3_ST	Q92934	BAD	P51812	RPS6KA3	S75	T80K	80	Missense	distal	5	no	4.372	4.318	PhosphoSitePlus;EPSD	ICGC	1.803	Down-regulation
AGC_RSK_RSKp90_RPS6KA3_ST	Q92934	BAD	P51812	RPS6KA3	S75	S74G	74	Missense	proximal	-1	no	4.372	4.335	PhosphoSitePlus;EPSD	ICGC;COSMIC	1.803	Down-regulation
AGC_RSK_RSKp90_RPS6KA3_ST	Q92934	BAD	P51812	RPS6KA3	S97	S99L	99	Missense	proximal	2	no	3.885	3.778	EPSD	ICGC	1.803	Down-regulation
AGC_RSK_RSKp90_RPS6KA3_ST	Q92934	BAD	P51812	RPS6KA3	S97	R94W	94	Missense	distal	-3	no	3.885	1.342	EPSD	ICGC	1.803	Loss
AGC_RSK_RSKp90_RPS6KA3_ST	Q92934	BAD	P51812	RPS6KA3	S99	S99L	99	Missense	central	0	yes	4.010	0.000	EPSD;PhosphoSitePlus	ICGC	1.803	Loss
AGC_RSK_RSKp90_RPS6KA3_ST	Q92934	BAD	P51812	RPS6KA3	S99	R94W	94	Missense	distal	-5	no	4.010	3.628	EPSD;PhosphoSitePlus	ICGC	1.803	Down-regulation
AGC_RSK_RSKp90_RPS6KA3_ST	Q92934	BAD	P51812	RPS6KA3	S118	R112S	112	Missense	distal	-6	no	4.319	4.271	EPSD	ICGC	1.803	Down-regulation
AGC_RSK_RSKp90_RPS6KA3_ST	Q92934	BAD	P51812	RPS6KA3	S144	R149L	149	Missense	distal	5	no	1.897	2.007	EPSD	ICGC;COSMIC	1.803	Up-regulation
AGC_RSK_RSKp90_RPS6KA3_ST	Q92934	BAD	P51812	RPS6KA3	S145	R149L	149	Missense	distal	4	no	3.509	3.575	EPSD	ICGC;COSMIC	1.803	Up-regulation
AGC_RSK_RSKp90_RPS6KA3_ST	Q92934	BAD	P51812	RPS6KA3	S164	S167F	167	Missense	distal	3	no	3.626	3.636	EPSD	ICGC	1.803	Up-regulation
AGC_RSK_RSKp90_RPS6KA3_ST	Q8IX03	WWC1	P51812	RPS6KA3	S33	R38Q	38	Missense	distal	5	no	3.708	3.775	EPSD	ICGC;COSMIC	1.803	Up-regulation
AGC_RSK_RSKp90_RPS6KA3_ST	Q8IX03	WWC1	P51812	RPS6KA3	S141	Q142H	142	Missense	proximal	1	no	1.934	1.954	EPSD	ICGC;COSMIC	1.803	Up-regulation
AGC_RSK_RSKp90_RPS6KA3_ST	Q8IX03	WWC1	P51812	RPS6KA3	S141	V146F	146	Missense	distal	5	no	1.934	1.954	EPSD	ICGC	1.803	Up-regulation
AGC_RSK_RSKp90_RPS6KA3_ST	Q8IX03	WWC1	P51812	RPS6KA3	S141	V134F	134	Missense	distal	-7	no	1.934	1.939	EPSD	ICGC;COSMIC	1.803	Up-regulation
AGC_RSK_RSKp90_RPS6KA3_ST	Q8IX03	WWC1	P51812	RPS6KA3	S141	W135L	135	Missense	distal	-6	no	1.934	1.932	EPSD	ICGC;COSMIC	1.803	Down-regulation
AGC_RSK_RSKp90_RPS6KA3_ST	Q8IX03	WWC1	P51812	RPS6KA3	S150	V146F	146	Missense	distal	-4	no	2.029	2.008	EPSD	ICGC	1.803	Down-regulation
AGC_RSK_RSKp90_RPS6KA3_ST	Q8IX03	WWC1	P51812	RPS6KA3	S150	S153C	153	Missense	distal	3	no	2.029	2.036	EPSD	ICGC;COSMIC	1.803	Up-regulation
AGC_RSK_RSKp90_RPS6KA3_ST	Q8IX03	WWC1	P51812	RPS6KA3	S150	S149L	149	Missense	proximal	-1	no	2.029	1.987	EPSD	ICGC	1.803	Down-regulation
AGC_RSK_RSKp90_RPS6KA3_ST	Q8IX03	WWC1	P51812	RPS6KA3	S150	K154R	154	Missense	distal	4	no	2.029	2.004	EPSD	ICGC;COSMIC	1.803	Down-regulation
AGC_RSK_RSKp90_RPS6KA3_ST	Q8IX03	WWC1	P51812	RPS6KA3	S255	R250C	250	Missense	distal	-5	no	1.978	1.577	EPSD	ICGC;COSMIC	1.803	Loss
AGC_RSK_RSKp90_RPS6KA3_ST	Q8IX03	WWC1	P51812	RPS6KA3	S255	D252V	252	Missense	distal	-3	no	1.978	1.725	EPSD	ICGC;COSMIC	1.803	Loss
AGC_RSK_RSKp90_RPS6KA3_ST	Q8IX03	WWC1	P51812	RPS6KA3	S255	S255Y	255	Missense	central	0	yes	1.978	0.000	EPSD	ICGC;COSMIC	1.803	Loss
AGC_RSK_RSKp90_RPS6KA3_ST	Q8IX03	WWC1	P51812	RPS6KA3	S268	L266V	266	Missense	proximal	-2	no	1.826	1.708	EPSD	ICGC;COSMIC	1.803	Loss
AGC_RSK_RSKp90_RPS6KA3_ST	Q8IX03	WWC1	P51812	RPS6KA3	S268	P274L	274	Missense	distal	6	no	1.826	1.808	EPSD	ICGC	1.803	Down-regulation
AGC_RSK_RSKp90_RPS6KA3_ST	Q8IX03	WWC1	P51812	RPS6KA3	S268	S268I	268	Missense	central	0	yes	1.826	0.000	EPSD	ICGC;COSMIC	1.803	Loss
AGC_RSK_RSKp90_RPS6KA3_ST	Q8IX03	WWC1	P51812	RPS6KA3	S270	L266V	266	Missense	distal	-4	no	1.810	1.780	EPSD	ICGC;COSMIC	1.803	Loss
AGC_RSK_RSKp90_RPS6KA3_ST	Q8IX03	WWC1	P51812	RPS6KA3	S270	P274L	274	Missense	distal	4	no	1.810	1.840	EPSD	ICGC	1.803	Up-regulation
AGC_RSK_RSKp90_RPS6KA3_ST	Q8IX03	WWC1	P51812	RPS6KA3	S270	Y277C	277	Missense	distal	7	no	1.810	1.808	EPSD	ICGC;COSMIC;CCLE	1.803	Down-regulation
AGC_RSK_RSKp90_RPS6KA3_ST	Q8IX03	WWC1	P51812	RPS6KA3	S270	S268I	268	Missense	proximal	-2	no	1.810	1.681	EPSD	ICGC;COSMIC	1.803	Loss
AGC_RSK_RSKp90_RPS6KA3_ST	Q8IX03	WWC1	P51812	RPS6KA3	S358	R355C	355	Missense	distal	-3	no	3.731	1.120	EPSD	ICGC;COSMIC	1.803	Loss
AGC_RSK_RSKp90_RPS6KA3_ST	Q8IX03	WWC1	P51812	RPS6KA3	S358	K352R	352	Missense	distal	-6	no	3.731	3.784	EPSD	ICGC;COSMIC	1.803	Up-regulation
AGC_RSK_RSKp90_RPS6KA3_ST	Q8IX03	WWC1	P51812	RPS6KA3	S437	L442I	442	Missense	distal	5	no	1.936	1.918	EPSD	ICGC;COSMIC	1.803	Down-regulation
AGC_RSK_RSKp90_RPS6KA3_ST	Q8IX03	WWC1	P51812	RPS6KA3	S438	L442I	442	Missense	distal	4	no	2.135	2.124	EPSD	ICGC;COSMIC	1.803	Down-regulation
AGC_RSK_RSKp90_RPS6KA3_ST	Q8IX03	WWC1	P51812	RPS6KA3	S441	L442I	442	Missense	proximal	1	no	1.947	1.938	EPSD	ICGC;COSMIC	1.803	Down-regulation
AGC_RSK_RSKp90_RPS6KA3_ST	Q8IX03	WWC1	P51812	RPS6KA3	S523	A520S	520	Missense	distal	-3	no	1.733	1.836	EPSD	ICGC	1.803	Gain
AGC_RSK_RSKp90_RPS6KA3_ST	Q8IX03	WWC1	P51812	RPS6KA3	S525	T527I	527	Missense	proximal	2	no	4.098	4.133	EPSD	ICGC;COSMIC	1.803	Up-regulation
AGC_RSK_RSKp90_RPS6KA3_ST	Q8IX03	WWC1	P51812	RPS6KA3	S525	A520S	520	Missense	distal	-5	no	4.098	4.095	EPSD	ICGC	1.803	Down-regulation
AGC_RSK_RSKp90_RPS6KA3_ST	Q8IX03	WWC1	P51812	RPS6KA3	S533	S539P	539	Missense	distal	6	no	2.203	2.168	EPSD	ICGC;COSMIC	1.803	Down-regulation
AGC_RSK_RSKp90_RPS6KA3_ST	Q8IX03	WWC1	P51812	RPS6KA3	S533	T527I	527	Missense	distal	-6	no	2.203	2.207	EPSD	ICGC;COSMIC	1.803	Up-regulation
AGC_RSK_RSKp90_RPS6KA3_ST	Q8IX03	WWC1	P51812	RPS6KA3	S533	S535F	535	Missense	proximal	2	no	2.203	2.071	EPSD	ICGC	1.803	Down-regulation
AGC_RSK_RSKp90_RPS6KA3_ST	Q8IX03	WWC1	P51812	RPS6KA3	S539	P536Q	536	Missense	distal	-3	no	2.227	1.835	EPSD	ICGC;COSMIC	1.803	Down-regulation
AGC_RSK_RSKp90_RPS6KA3_ST	Q8IX03	WWC1	P51812	RPS6KA3	S539	S539P	539	Missense	central	0	yes	2.227	0.000	EPSD	ICGC;COSMIC	1.803	Loss
AGC_RSK_RSKp90_RPS6KA3_ST	Q8IX03	WWC1	P51812	RPS6KA3	S539	S542T	542	Missense	distal	3	no	2.227	2.235	EPSD	ICGC;COSMIC	1.803	Up-regulation
AGC_RSK_RSKp90_RPS6KA3_ST	Q8IX03	WWC1	P51812	RPS6KA3	S539	S535F	535	Missense	distal	-4	no	2.227	2.084	EPSD	ICGC	1.803	Down-regulation
AGC_RSK_RSKp90_RPS6KA3_ST	Q8IX03	WWC1	P51812	RPS6KA3	S539	S541F	541	Missense	proximal	2	no	2.227	2.095	EPSD	ICGC	1.803	Down-regulation
AGC_RSK_RSKp90_RPS6KA3_ST	Q8IX03	WWC1	P51812	RPS6KA3	S542	P536Q	536	Missense	distal	-6	no	2.417	2.415	EPSD	ICGC;COSMIC	1.803	Down-regulation
AGC_RSK_RSKp90_RPS6KA3_ST	Q8IX03	WWC1	P51812	RPS6KA3	S542	S539P	539	Missense	distal	-3	no	2.417	2.310	EPSD	ICGC;COSMIC	1.803	Down-regulation
AGC_RSK_RSKp90_RPS6KA3_ST	Q8IX03	WWC1	P51812	RPS6KA3	S542	S535F	535	Missense	distal	-7	no	2.417	2.443	EPSD	ICGC	1.803	Up-regulation
AGC_RSK_RSKp90_RPS6KA3_ST	Q8IX03	WWC1	P51812	RPS6KA3	S542	S541F	541	Missense	proximal	-1	no	2.417	2.357	EPSD	ICGC	1.803	Down-regulation
AGC_RSK_RSKp90_RPS6KA3_ST	Q8IX03	WWC1	P51812	RPS6KA3	S785	W780R	780	Missense	distal	-5	no	1.725	2.107	EPSD	ICGC;COSMIC	1.803	Gain
AGC_RSK_RSKp90_RPS6KA3_ST	Q8IX03	WWC1	P51812	RPS6KA3	S793	K791R	791	Missense	proximal	-2	no	1.593	2.013	EPSD	ICGC	1.803	Gain
AGC_RSK_RSKp90_RPS6KA3_ST	Q8IX03	WWC1	P51812	RPS6KA3	T912	R908W	908	Missense	distal	-4	no	1.905	1.714	EPSD	ICGC;COSMIC	1.803	Loss
AGC_RSK_RSKp90_RPS6KA3_ST	Q8IX03	WWC1	P51812	RPS6KA3	T912	V910L	910	Missense	proximal	-2	no	1.905	2.022	EPSD	ICGC	1.803	Up-regulation
AGC_RSK_RSKp90_RPS6KA3_ST	Q8IX03	WWC1	P51812	RPS6KA3	S974	S975L	975	Missense	proximal	1	no	2.314	2.374	EPSD	ICGC;COSMIC	1.803	Up-regulation
AGC_RSK_RSKp90_RPS6KA3_ST	Q8IX03	WWC1	P51812	RPS6KA3	S974	R980H	980	Missense	distal	6	no	2.314	2.247	EPSD	ICGC;COSMIC	1.803	Down-regulation
AGC_RSK_RSKp90_RPS6KA3_ST	Q8IX03	WWC1	P51812	RPS6KA3	S974	P973L	973	Missense	proximal	-1	no	2.314	2.299	EPSD	ICGC;COSMIC	1.803	Down-regulation
AGC_RSK_RSKp90_RPS6KA3_ST	Q8IX03	WWC1	P51812	RPS6KA3	S974	R980C	980	Missense	distal	6	no	2.314	2.243	EPSD	ICGC;COSMIC	1.803	Down-regulation
AGC_RSK_RSKp90_RPS6KA3_ST	Q8IX03	WWC1	P51812	RPS6KA3	S974	S981C	981	Missense	distal	7	no	2.314	2.358	EPSD	ICGC;COSMIC	1.803	Up-regulation
AGC_RSK_RSKp90_RPS6KA3_ST	Q8IX03	WWC1	P51812	RPS6KA3	S974	P973S	973	Missense	proximal	-1	no	2.314	2.341	EPSD	ICGC;COSMIC	1.803	Up-regulation
AGC_RSK_RSKp90_RPS6KA3_ST	Q8IX03	WWC1	P51812	RPS6KA3	S975	S975L	975	Missense	central	0	yes	3.999	0.000	EPSD	ICGC;COSMIC	1.803	Loss
AGC_RSK_RSKp90_RPS6KA3_ST	Q8IX03	WWC1	P51812	RPS6KA3	S975	R980H	980	Missense	distal	5	no	3.999	4.092	EPSD	ICGC;COSMIC	1.803	Up-regulation
AGC_RSK_RSKp90_RPS6KA3_ST	Q8IX03	WWC1	P51812	RPS6KA3	S975	P973L	973	Missense	proximal	-2	no	3.999	3.963	EPSD	ICGC;COSMIC	1.803	Down-regulation
AGC_RSK_RSKp90_RPS6KA3_ST	Q8IX03	WWC1	P51812	RPS6KA3	S975	E982K	982	Missense	distal	7	no	3.999	3.985	EPSD	ICGC;COSMIC	1.803	Down-regulation
AGC_RSK_RSKp90_RPS6KA3_ST	Q8IX03	WWC1	P51812	RPS6KA3	S975	R980C	980	Missense	distal	5	no	3.999	4.101	EPSD	ICGC;COSMIC	1.803	Up-regulation
AGC_RSK_RSKp90_RPS6KA3_ST	Q8IX03	WWC1	P51812	RPS6KA3	S975	S981C	981	Missense	distal	6	no	3.999	3.947	EPSD	ICGC;COSMIC	1.803	Down-regulation
AGC_RSK_RSKp90_RPS6KA3_ST	Q8IX03	WWC1	P51812	RPS6KA3	S975	P973S	973	Missense	proximal	-2	no	3.999	4.054	EPSD	ICGC;COSMIC	1.803	Up-regulation
AGC_RSK_RSKp90_RPS6KA3_ST	Q8IX03	WWC1	P51812	RPS6KA3	S978	S975L	975	Missense	distal	-3	no	1.965	1.741	EPSD	ICGC;COSMIC	1.803	Loss
AGC_RSK_RSKp90_RPS6KA3_ST	Q8IX03	WWC1	P51812	RPS6KA3	S978	R983C	983	Missense	distal	5	no	1.965	2.067	EPSD	ICGC;COSMIC	1.803	Up-regulation
AGC_RSK_RSKp90_RPS6KA3_ST	Q8IX03	WWC1	P51812	RPS6KA3	S978	R980H	980	Missense	proximal	2	no	1.965	1.864	EPSD	ICGC;COSMIC	1.803	Down-regulation
AGC_RSK_RSKp90_RPS6KA3_ST	Q8IX03	WWC1	P51812	RPS6KA3	S978	P973L	973	Missense	distal	-5	no	1.965	1.943	EPSD	ICGC;COSMIC	1.803	Down-regulation
AGC_RSK_RSKp90_RPS6KA3_ST	Q8IX03	WWC1	P51812	RPS6KA3	S978	E982K	982	Missense	distal	4	no	1.965	1.951	EPSD	ICGC;COSMIC	1.803	Down-regulation
AGC_RSK_RSKp90_RPS6KA3_ST	Q8IX03	WWC1	P51812	RPS6KA3	S978	R980C	980	Missense	proximal	2	no	1.965	1.857	EPSD	ICGC;COSMIC	1.803	Down-regulation
AGC_RSK_RSKp90_RPS6KA3_ST	Q8IX03	WWC1	P51812	RPS6KA3	S978	S981C	981	Missense	distal	3	no	1.965	1.972	EPSD	ICGC;COSMIC	1.803	Up-regulation
AGC_RSK_RSKp90_RPS6KA3_ST	Q8IX03	WWC1	P51812	RPS6KA3	S978	R983P	983	Missense	distal	5	no	1.965	2.037	EPSD	ICGC;COSMIC	1.803	Up-regulation
AGC_RSK_RSKp90_RPS6KA3_ST	Q8IX03	WWC1	P51812	RPS6KA3	S978	R983H	983	Missense	distal	5	no	1.965	2.058	EPSD	ICGC;COSMIC	1.803	Up-regulation
AGC_RSK_RSKp90_RPS6KA3_ST	Q8IX03	WWC1	P51812	RPS6KA3	S978	P973S	973	Missense	distal	-5	no	1.965	1.972	EPSD	ICGC;COSMIC	1.803	Up-regulation
AGC_RSK_RSKp90_RPS6KA3_ST	Q8IX03	WWC1	P51812	RPS6KA3	S981	R986H	986	Missense	distal	5	no	1.710	1.803	EPSD	ICGC;COSMIC	1.803	Gain
AGC_RSK_RSKp90_RPS6KA3_ST	Q8IX03	WWC1	P51812	RPS6KA3	S1081	R1078Q	1078	Missense	distal	-3	no	4.094	1.588	EPSD	ICGC;COSMIC	1.803	Loss
AGC_RSK_RSKp90_RPS6KA3_ST	Q8IX03	WWC1	P51812	RPS6KA3	S1081	R1076S	1076	Missense	distal	-5	no	4.094	3.778	EPSD	ICGC	1.803	Down-regulation
AGC_RSK_RSKp90_RPS6KA3_ST	Q8IX03	WWC1	P51812	RPS6KA3	S1081	G1079D	1079	Missense	proximal	-2	no	4.094	4.054	EPSD	ICGC;COSMIC	1.803	Down-regulation
AGC_RSK_RSKp90_RPS6KA3_ST	Q8IX03	WWC1	P51812	RPS6KA3	S1081	P1086S	1086	Missense	distal	5	no	4.094	4.054	EPSD	ICGC;COSMIC	1.803	Down-regulation
AGC_RSK_RSKp90_RPS6KA3_ST	P16220	CREB1	P51812	RPS6KA3	S133	D140A	140	Missense	distal	7	no	4.306	4.282	PhosphoSitePlus	ICGC;COSMIC	1.803	Down-regulation
AGC_RSK_RSKp90_RPS6KA3_ST	P16220	CREB1	P51812	RPS6KA3	S143	D140A	140	Missense	distal	-3	no	1.387	1.847	EPSD	ICGC;COSMIC	1.803	Gain
AGC_RSK_RSKp90_RPS6KA3_ST	P49841	GSK3B	P51812	RPS6KA3	T7	A11S	11	Missense	distal	4	no	2.033	2.008	EPSD	ICGC;COSMIC	1.803	Down-regulation
AGC_RSK_RSKp90_RPS6KA3_ST	P49841	GSK3B	P51812	RPS6KA3	S9	A11S	11	Missense	proximal	2	no	4.283	4.343	PhosphoSitePlus	ICGC;COSMIC	1.803	Up-regulation
AGC_RSK_RSKp90_RPS6KA3_ST	P49841	GSK3B	P51812	RPS6KA3	S35	D33E	33	Missense	proximal	-2	no	1.823	1.866	EPSD	ICGC	1.803	Up-regulation
AGC_RSK_RSKp90_RPS6KA3_ST	P49841	GSK3B	P51812	RPS6KA3	S55	Q52K	52	Missense	distal	-3	no	1.299	1.839	EPSD	ICGC	1.803	Gain
AGC_RSK_RSKp90_RPS6KA3_ST	P49841	GSK3B	P51812	RPS6KA3	S147	P154H	154	Missense	distal	7	no	3.392	3.403	EPSD	ICGC;COSMIC	1.803	Up-regulation
AGC_RSK_RSKp90_RPS6KA3_ST	P49841	GSK3B	P51812	RPS6KA3	S147	A149D	149	Missense	proximal	2	no	3.392	3.349	EPSD	ICGC	1.803	Down-regulation
AGC_RSK_RSKp90_RPS6KA3_ST	P49841	GSK3B	P51812	RPS6KA3	S147	T152R	152	Missense	distal	5	no	3.392	3.287	EPSD	ICGC;COSMIC	1.803	Down-regulation
AGC_RSK_RSKp90_RPS6KA3_ST	P49841	GSK3B	P51812	RPS6KA3	S147	Q151R	151	Missense	distal	4	no	3.392	3.358	EPSD	ICGC;COSMIC	1.803	Down-regulation
AGC_RSK_RSKp90_RPS6KA3_ST	P49841	GSK3B	P51812	RPS6KA3	S215	S219Y	219	Missense	distal	4	no	1.751	1.818	EPSD	ICGC;COSMIC	1.803	Gain
AGC_RSK_RSKp90_RPS6KA3_ST	P49841	GSK3B	P51812	RPS6KA3	T408	G406R	406	Missense	proximal	-2	no	1.627	2.160	EPSD	ICGC;COSMIC	1.803	Gain
AGC_RSK_RSKp90_RPS6KA3_ST	Q9H6Z4	RANBP3	P51812	RPS6KA3	S35	R42L	42	Missense	distal	7	no	1.785	1.841	EPSD	ICGC;COSMIC	1.803	Gain
AGC_RSK_RSKp90_RPS6KA3_ST	Q9H6Z4	RANBP3	P51812	RPS6KA3	S221	E226D	226	Missense	distal	5	no	3.790	3.812	EPSD	ICGC;COSMIC	1.803	Up-regulation
AGC_RSK_RSKp90_RPS6KA3_ST	P07101	TH	P51812	RPS6KA3	S19	E20Q	20	Missense	proximal	1	no	3.611	3.603	EPSD	ICGC;COSMIC	1.803	Down-regulation
AGC_RSK_RSKp90_RPS6KA3_ST	P07101	TH	P51812	RPS6KA3	S19	K12R	12	Missense	distal	-7	no	3.611	3.596	EPSD	ICGC;COSMIC	1.803	Down-regulation
AGC_RSK_RSKp90_RPS6KA3_ST	P19525	EIF2AK2	P51812	RPS6KA3	T42	H37N	37	Missense	distal	-5	no	2.820	2.883	EPSD	ICGC	1.803	Up-regulation
AGC_RSK_RSKp90_RPS6KA3_ST	P19525	EIF2AK2	P51812	RPS6KA3	S143	Q139K	139	Missense	distal	-4	no	1.800	1.839	EPSD	ICGC	1.803	Gain
AGC_RSK_RSKp90_RPS6KA3_ST	P19525	EIF2AK2	P51812	RPS6KA3	S143	K150E	150	Missense	distal	7	no	1.800	1.815	EPSD	ICGC	1.803	Gain
AGC_RSK_RSKp90_RPS6KA3_ST	P19525	EIF2AK2	P51812	RPS6KA3	S181	T185A	185	Missense	distal	4	no	1.851	1.800	EPSD	ICGC;COSMIC	1.803	Loss
AGC_RSK_RSKp90_RPS6KA3_ST	P19525	EIF2AK2	P51812	RPS6KA3	S242	L243S	243	Missense	proximal	1	no	2.402	2.343	EPSD	ICGC;COSMIC	1.803	Down-regulation
AGC_RSK_RSKp90_RPS6KA3_ST	P19525	EIF2AK2	P51812	RPS6KA3	S456	T451N	451	Missense	distal	-5	no	3.709	3.753	EPSD	ICGC	1.803	Up-regulation
AGC_RSK_RSKp90_RPS6KA3_ST	P19525	EIF2AK2	P51812	RPS6KA3	S456	Q459K	459	Missense	distal	3	no	3.709	3.708	EPSD	ICGC	1.803	Down-regulation
AGC_RSK_RSKp90_RPS6KA3_ST	P19525	EIF2AK2	P51812	RPS6KA3	S462	Q459K	459	Missense	distal	-3	no	1.404	1.943	EPSD	ICGC	1.803	Gain
AGC_RSK_RSKp90_RPS6KA3_ST	P19525	EIF2AK2	P51812	RPS6KA3	T529	P523T	523	Missense	distal	-6	no	2.234	2.216	EPSD	ICGC;COSMIC	1.803	Down-regulation
AGC_RSK_RSKp90_RPS6KA3_ST	P19525	EIF2AK2	P51812	RPS6KA3	T529	R526Q	526	Missense	distal	-3	no	2.234	-0.273	EPSD	ICGC	1.803	Loss
AGC_RSK_RSKp90_RPS6KA3_ST	P19525	EIF2AK2	P51812	RPS6KA3	S530	P523T	523	Missense	distal	-7	no	1.974	1.984	EPSD	ICGC;COSMIC	1.803	Up-regulation
AGC_RSK_RSKp90_RPS6KA3_ST	P19525	EIF2AK2	P51812	RPS6KA3	S530	R526Q	526	Missense	distal	-4	no	1.974	1.808	EPSD	ICGC	1.803	Down-regulation
AGC_RSK_RSKp90_RPS6KA3_ST	P03372	ESR1	P51812	RPS6KA3	S154	S154L	154	Missense	central	0	yes	3.503	0.000	EPSD	ICGC	1.803	Loss
AGC_RSK_RSKp90_RPS6KA3_ST	P03372	ESR1	P51812	RPS6KA3	S154	R158H	158	Missense	distal	4	no	3.503	3.555	EPSD	ICGC;COSMIC;CCLE	1.803	Up-regulation
AGC_RSK_RSKp90_RPS6KA3_ST	P03372	ESR1	P51812	RPS6KA3	S154	N153K	153	Missense	proximal	-1	no	3.503	3.517	EPSD	ICGC	1.803	Up-regulation
AGC_RSK_RSKp90_RPS6KA3_ST	P03372	ESR1	P51812	RPS6KA3	S154	P147L	147	Missense	distal	-7	no	3.503	3.512	EPSD	ICGC;COSMIC	1.803	Up-regulation
AGC_RSK_RSKp90_RPS6KA3_ST	P03372	ESR1	P51812	RPS6KA3	S167	E163Q	163	Missense	distal	-4	no	4.193	4.197	PhosphoSitePlus	ICGC;COSMIC	1.803	Up-regulation
AGC_RSK_RSKp90_RPS6KA3_ST	P03372	ESR1	P51812	RPS6KA3	S236	Q238R	238	Missense	proximal	2	no	4.297	4.379	EPSD	ICGC	1.803	Up-regulation
AGC_RSK_RSKp90_RPS6KA3_ST	P03372	ESR1	P51812	RPS6KA3	S236	L242I	242	Missense	distal	6	no	4.297	4.301	EPSD	ICGC	1.803	Up-regulation
AGC_RSK_RSKp90_RPS6KA3_ST	P03372	ESR1	P51812	RPS6KA3	S236	R233M	233	Missense	distal	-3	no	4.297	1.980	EPSD	ICGC;COSMIC	1.803	Down-regulation
AGC_RSK_RSKp90_RPS6KA3_ST	P03372	ESR1	P51812	RPS6KA3	S305	K302T	302	Missense	distal	-3	no	1.964	1.491	EPSD	ICGC;COSMIC	1.803	Loss
AGC_RSK_RSKp90_RPS6KA3_ST	P03372	ESR1	P51812	RPS6KA3	S305	R300L	300	Missense	distal	-5	no	1.964	1.618	EPSD	ICGC;COSMIC	1.803	Loss
AGC_RSK_RSKp90_RPS6KA3_ST	P03372	ESR1	P51812	RPS6KA3	S305	R300S	300	Missense	distal	-5	no	1.964	1.647	EPSD	ICGC;COSMIC	1.803	Loss
AGC_RSK_RSKp90_RPS6KA3_ST	P03372	ESR1	P51812	RPS6KA3	S305	R300H	300	Missense	distal	-5	no	1.964	1.580	EPSD	ICGC;COSMIC	1.803	Loss
AGC_RSK_RSKp90_RPS6KA3_ST	P03372	ESR1	P51812	RPS6KA3	S554	R555L	555	Missense	proximal	1	no	1.730	1.831	EPSD	ICGC	1.803	Gain
AGC_RSK_RSKp90_RPS6KA3_ST	P62753	RPS6	P51812	RPS6KA3	T34	A33D	33	Missense	proximal	-1	no	2.055	2.031	EPSD	ICGC	1.803	Down-regulation
AGC_RSK_RSKp90_RPS6KA3_ST	P62753	RPS6	P51812	RPS6KA3	T34	R31C	31	Missense	distal	-3	no	2.055	-0.556	EPSD	ICGC	1.803	Loss
AGC_RSK_RSKp90_RPS6KA3_ST	P62753	RPS6	P51812	RPS6KA3	S235	A229S	229	Missense	distal	-6	no	4.089	4.100	EPSD;PhosphoSitePlus	ICGC;COSMIC	1.803	Up-regulation
AGC_RSK_RSKp90_RPS6KA3_ST	P62753	RPS6	P51812	RPS6KA3	S235	A229V	229	Missense	distal	-6	no	4.089	4.055	EPSD;PhosphoSitePlus	ICGC;COSMIC;GDSC;CCLE	1.803	Down-regulation
AGC_RSK_RSKp90_RPS6KA3_ST	P62753	RPS6	P51812	RPS6KA3	S236	A229S	229	Missense	distal	-7	no	4.462	4.457	PhosphoSitePlus;EPSD	ICGC;COSMIC	1.803	Down-regulation
AGC_RSK_RSKp90_RPS6KA3_ST	P62753	RPS6	P51812	RPS6KA3	S236	A229V	229	Missense	distal	-7	no	4.462	4.477	PhosphoSitePlus;EPSD	ICGC;COSMIC;GDSC;CCLE	1.803	Up-regulation
AGC_RSK_RSKp90_RPS6KA3_ST	P67809	YBX1	P51812	RPS6KA3	T80	K81E	81	Missense	proximal	1	no	1.873	1.896	EPSD	ICGC;COSMIC	1.803	Up-regulation
AGC_RSK_RSKp90_RPS6KA3_ST	P67809	YBX1	P51812	RPS6KA3	T80	V84L	84	Missense	distal	4	no	1.873	1.875	EPSD	ICGC;COSMIC	1.803	Up-regulation
AGC_RSK_RSKp90_RPS6KA3_ST	P67809	YBX1	P51812	RPS6KA3	T80	D79Y	79	Missense	proximal	-1	no	1.873	1.870	EPSD	ICGC	1.803	Down-regulation
AGC_RSK_RSKp90_RPS6KA3_ST	P67809	YBX1	P51812	RPS6KA3	S102	D105G	105	Missense	distal	3	no	1.917	1.918	PhosphoSitePlus	ICGC;COSMIC	1.803	Up-regulation
AGC_RSK_RSKp90_RPS6KA3_ST	Q9BSI4	TINF2	P51812	RPS6KA3	S324	G319V	319	Missense	distal	-5	no	3.280	3.219	EPSD	ICGC;COSMIC	1.803	Down-regulation
AGC_RSK_RSKp90_RPS6KA3_ST	Q9BSI4	TINF2	P51812	RPS6KA3	S324	A322E	322	Missense	proximal	-2	no	3.280	3.202	EPSD	ICGC	1.803	Down-regulation
AGC_RSK_RSKp90_RPS6KA3_ST	Q9BSI4	TINF2	P51812	RPS6KA3	S324	A317V	317	Missense	distal	-7	no	3.280	3.295	EPSD	ICGC	1.803	Up-regulation
AGC_RSK_RSKp90_RPS6KA3_ST	Q9BSI4	TINF2	P51812	RPS6KA3	S324	A323T	323	Missense	proximal	-1	no	3.280	3.251	EPSD	ICGC;COSMIC	1.803	Down-regulation
AGC_RSK_RSKp90_RPS6KA3_ST	Q9BSI4	TINF2	P51812	RPS6KA3	S330	A323T	323	Missense	distal	-7	no	2.111	2.126	EPSD;PhosphoSitePlus	ICGC;COSMIC	1.803	Up-regulation
AGC_RSK_RSKp90_RPS6KA3_ST	Q9NYV6	RRN3	P51812	RPS6KA3	S17	S18F	18	Missense	proximal	1	no	1.842	1.926	EPSD	ICGC	1.803	Up-regulation
AGC_RSK_RSKp90_RPS6KA3_ST	Q9NYV6	RRN3	P51812	RPS6KA3	S17	K22N	22	Missense	distal	5	no	1.842	1.868	EPSD	ICGC;COSMIC	1.803	Up-regulation
AGC_RSK_RSKp90_RPS6KA3_ST	Q9NYV6	RRN3	P51812	RPS6KA3	S17	A16T	16	Missense	proximal	-1	no	1.842	1.813	EPSD	ICGC;COSMIC	1.803	Down-regulation
AGC_RSK_RSKp90_RPS6KA3_ST	P13796	LCP1	P51812	RPS6KA3	T54	R49K	49	Missense	distal	-5	no	2.019	1.732	EPSD	ICGC;COSMIC	1.803	Loss
AGC_RSK_RSKp90_RPS6KA3_ST	P13796	LCP1	P51812	RPS6KA3	T54	Y48H	48	Missense	distal	-6	no	2.019	2.027	EPSD	ICGC	1.803	Up-regulation
AGC_RSK_RSKp90_RPS6KA3_ST	P13796	LCP1	P51812	RPS6KA3	S202	A201D	201	Missense	proximal	-1	no	1.948	1.925	EPSD	ICGC	1.803	Down-regulation
AGC_RSK_RSKp90_RPS6KA3_ST	P13796	LCP1	P51812	RPS6KA3	S202	N195K	195	Missense	distal	-7	no	1.948	1.941	EPSD	ICGC	1.803	Down-regulation
AGC_RSK_RSKp90_RPS6KA3_ST	P13796	LCP1	P51812	RPS6KA3	S202	I204S	204	Missense	proximal	2	no	1.948	2.043	EPSD	ICGC;COSMIC	1.803	Up-regulation
AGC_RSK_RSKp90_RPS6KA3_ST	P13796	LCP1	P51812	RPS6KA3	S202	V209I	209	Missense	distal	7	no	1.948	1.938	EPSD	ICGC	1.803	Down-regulation
AGC_RSK_RSKp90_RPS6KA3_ST	P19105	MYL12A	P51812	RPS6KA3	S19	Q15K	15	Missense	distal	-4	no	3.466	3.505	PhosphoSitePlus	ICGC;COSMIC	1.803	Up-regulation
AGC_RSK_RSKp90_RPS6KA3_ST	P19105	MYL12A	P51812	RPS6KA3	S19	A23S	23	Missense	distal	4	no	3.466	3.441	PhosphoSitePlus	ICGC;COSMIC	1.803	Down-regulation
AGC_RSK_RSKp90_RPS6KA3_ST	Q9UL17	TBX21	P51812	RPS6KA3	S394	A401V	401	Missense	distal	7	no	3.886	3.917	EPSD	ICGC;COSMIC	1.803	Up-regulation
AGC_RSK_RSKp90_RPS6KA3_ST	Q9UL17	TBX21	P51812	RPS6KA3	S403	A401V	401	Missense	proximal	-2	no	3.868	3.697	EPSD	ICGC;COSMIC	1.803	Down-regulation
AGC_RSK_RSKp90_RPS6KA3_ST	Q9UL17	TBX21	P51812	RPS6KA3	S403	P406T	406	Missense	distal	3	no	3.868	3.872	EPSD	ICGC	1.803	Up-regulation
AGC_RSK_RSKp90_RPS6KA3_ST	Q9UL17	TBX21	P51812	RPS6KA3	S403	M404L	404	Missense	proximal	1	no	3.868	3.891	EPSD	ICGC;COSMIC	1.803	Up-regulation
AGC_RSK_RSKp90_RPS6KA3_ST	Q9UL17	TBX21	P51812	RPS6KA3	S403	A407E	407	Missense	distal	4	no	3.868	3.885	EPSD	ICGC;COSMIC	1.803	Up-regulation
AGC_RSK_RSKp90_RPS6KA3_ST	Q9UL17	TBX21	P51812	RPS6KA3	S503	R500W	500	Missense	distal	-3	no	4.048	1.506	PhosphoSitePlus;EPSD	ICGC;COSMIC	1.803	Loss
AGC_RSK_RSKp90_RPS6KA3_ST	Q9UL17	TBX21	P51812	RPS6KA3	S503	S508I	508	Missense	distal	5	no	4.048	4.108	PhosphoSitePlus;EPSD	ICGC	1.803	Up-regulation
AGC_RSK_RSKp90_RPS6KA3_ST	Q9UL17	TBX21	P51812	RPS6KA3	S503	P506H	506	Missense	distal	3	no	4.048	4.050	PhosphoSitePlus;EPSD	ICGC;COSMIC	1.803	Up-regulation
AGC_RSK_RSKp90_RPS6KA3_ST	Q9UL17	TBX21	P51812	RPS6KA3	S507	R500W	500	Missense	distal	-7	no	1.879	1.905	EPSD;PhosphoSitePlus	ICGC;COSMIC	1.803	Up-regulation
AGC_RSK_RSKp90_RPS6KA3_ST	Q9UL17	TBX21	P51812	RPS6KA3	S507	S511I	511	Missense	distal	4	no	1.879	1.937	EPSD;PhosphoSitePlus	ICGC;COSMIC	1.803	Up-regulation
AGC_RSK_RSKp90_RPS6KA3_ST	Q9UL17	TBX21	P51812	RPS6KA3	S507	S508I	508	Missense	proximal	1	no	1.879	1.929	EPSD;PhosphoSitePlus	ICGC	1.803	Up-regulation
AGC_RSK_RSKp90_RPS6KA3_ST	Q9UL17	TBX21	P51812	RPS6KA3	S507	P506H	506	Missense	proximal	-1	no	1.879	1.866	EPSD;PhosphoSitePlus	ICGC;COSMIC	1.803	Down-regulation
AGC_RSK_RSKp90_RPS6KA3_ST	P53355	DAPK1	P51812	RPS6KA3	S57	R53W	53	Missense	distal	-4	no	3.715	3.525	EPSD	ICGC;COSMIC	1.803	Down-regulation
AGC_RSK_RSKp90_RPS6KA3_ST	P53355	DAPK1	P51812	RPS6KA3	S57	R63L	63	Missense	distal	6	no	3.715	3.644	EPSD	ICGC;COSMIC	1.803	Down-regulation
AGC_RSK_RSKp90_RPS6KA3_ST	P53355	DAPK1	P51812	RPS6KA3	S57	R54L	54	Missense	distal	-3	no	3.715	1.484	EPSD	ICGC;COSMIC;GDSC;CCLE	1.803	Loss
AGC_RSK_RSKp90_RPS6KA3_ST	P53355	DAPK1	P51812	RPS6KA3	S66	R63L	63	Missense	distal	-3	no	3.996	1.765	EPSD	ICGC;COSMIC	1.803	Loss
AGC_RSK_RSKp90_RPS6KA3_ST	P53355	DAPK1	P51812	RPS6KA3	S289	M293I	293	Missense	distal	4	no	4.083	4.092	PhosphoSitePlus	ICGC;COSMIC	1.803	Up-regulation
AGC_RSK_RSKp90_RPS6KA3_ST	P53355	DAPK1	P51812	RPS6KA3	S313	R317G	317	Missense	distal	4	no	3.844	3.903	EPSD	ICGC;COSMIC	1.803	Up-regulation
AGC_RSK_RSKp90_RPS6KA3_ST	P53355	DAPK1	P51812	RPS6KA3	S313	S308F	308	Missense	distal	-5	no	3.844	3.711	EPSD	ICGC;COSMIC	1.803	Down-regulation
AGC_RSK_RSKp90_RPS6KA3_ST	P53355	DAPK1	P51812	RPS6KA3	S321	S321L	321	Missense	central	0	yes	1.807	0.000	EPSD	ICGC;COSMIC	1.803	Loss
AGC_RSK_RSKp90_RPS6KA3_ST	P53355	DAPK1	P51812	RPS6KA3	S321	R317G	317	Missense	distal	-4	no	1.807	1.633	EPSD	ICGC;COSMIC	1.803	Loss
AGC_RSK_RSKp90_RPS6KA3_ST	P53355	DAPK1	P51812	RPS6KA3	S329	S333R	333	Missense	distal	4	no	1.804	1.807	EPSD	ICGC	1.803	Up-regulation
AGC_RSK_RSKp90_RPS6KA3_ST	P53355	DAPK1	P51812	RPS6KA3	S762	E766K	766	Missense	distal	4	no	3.212	3.197	EPSD	ICGC;COSMIC	1.803	Down-regulation
AGC_RSK_RSKp90_RPS6KA3_ST	P53355	DAPK1	P51812	RPS6KA3	S762	S757I	757	Missense	distal	-5	no	3.212	3.159	EPSD	ICGC	1.803	Down-regulation
AGC_RSK_RSKp90_RPS6KA3_ST	P53355	DAPK1	P51812	RPS6KA3	S762	V758A	758	Missense	distal	-4	no	3.212	3.294	EPSD	ICGC;COSMIC	1.803	Up-regulation
AGC_RSK_RSKp90_RPS6KA3_ST	P53355	DAPK1	P51812	RPS6KA3	S762	R759K	759	Missense	distal	-3	no	3.212	1.245	EPSD	ICGC	1.803	Loss
AGC_RSK_RSKp90_RPS6KA3_ST	P53355	DAPK1	P51812	RPS6KA3	S1050	R1055L	1055	Missense	distal	5	no	1.769	1.879	EPSD	ICGC	1.803	Gain
AGC_RSK_RSKp90_RPS6KA3_ST	P53355	DAPK1	P51812	RPS6KA3	S1050	R1055Q	1055	Missense	distal	5	no	1.769	1.836	EPSD	ICGC;COSMIC	1.803	Gain
AGC_RSK_RSKp90_RPS6KA3_ST	Q16821	PPP1R3A	P51812	RPS6KA3	S46	I52V	52	Missense	distal	6	no	4.523	4.512	PhosphoSitePlus;EPSD	ICGC;COSMIC;GDSC;CCLE	1.803	Down-regulation
AGC_RSK_RSKp90_RPS6KA3_ST	Q16821	PPP1R3A	P51812	RPS6KA3	S48	I52V	52	Missense	distal	4	no	1.929	1.938	EPSD	ICGC;COSMIC;GDSC;CCLE	1.803	Up-regulation
AGC_RSK_RSKp90_RPS6KA3_ST	Q16821	PPP1R3A	P51812	RPS6KA3	S49	T56N	56	Missense	distal	7	no	1.834	1.816	EPSD	ICGC	1.803	Down-regulation
AGC_RSK_RSKp90_RPS6KA3_ST	Q16821	PPP1R3A	P51812	RPS6KA3	S49	I52V	52	Missense	distal	3	no	1.834	1.836	EPSD	ICGC;COSMIC;GDSC;CCLE	1.803	Up-regulation
AGC_RSK_RSKp90_RPS6KA3_ST	Q16821	PPP1R3A	P51812	RPS6KA3	S65	T61P	61	Missense	distal	-4	no	4.168	4.232	EPSD;PhosphoSitePlus	ICGC;COSMIC	1.803	Up-regulation
AGC_RSK_RSKp90_RPS6KA3_ST	Q16821	PPP1R3A	P51812	RPS6KA3	S65	A67D	67	Missense	proximal	2	no	4.168	4.125	EPSD;PhosphoSitePlus	ICGC;COSMIC	1.803	Down-regulation
AGC_RSK_RSKp90_RPS6KA3_ST	Q16821	PPP1R3A	P51812	RPS6KA3	S266	E263K	263	Missense	distal	-3	no	1.456	1.930	EPSD	ICGC	1.803	Gain
AGC_RSK_RSKp90_RPS6KA3_ST	Q16821	PPP1R3A	P51812	RPS6KA3	S332	R339M	339	Missense	distal	7	no	3.566	3.609	EPSD	ICGC;COSMIC	1.803	Up-regulation
AGC_RSK_RSKp90_RPS6KA3_ST	Q16821	PPP1R3A	P51812	RPS6KA3	S332	D337H	337	Missense	distal	5	no	3.566	3.560	EPSD	ICGC;COSMIC	1.803	Down-regulation
AGC_RSK_RSKp90_RPS6KA3_ST	Q16821	PPP1R3A	P51812	RPS6KA3	S332	R329K	329	Missense	distal	-3	no	3.566	1.599	EPSD	ICGC	1.803	Loss
AGC_RSK_RSKp90_RPS6KA3_ST	Q16821	PPP1R3A	P51812	RPS6KA3	S332	T330S	330	Missense	proximal	-2	no	3.566	3.701	EPSD	ICGC;COSMIC	1.803	Up-regulation
AGC_RSK_RSKp90_RPS6KA3_ST	Q16821	PPP1R3A	P51812	RPS6KA3	S332	S332N	332	Missense	central	0	yes	3.566	0.000	EPSD	ICGC	1.803	Loss
AGC_RSK_RSKp90_RPS6KA3_ST	Q16821	PPP1R3A	P51812	RPS6KA3	S375	S379L	379	Missense	distal	4	no	3.509	3.578	EPSD	ICGC;COSMIC	1.803	Up-regulation
AGC_RSK_RSKp90_RPS6KA3_ST	Q16821	PPP1R3A	P51812	RPS6KA3	S375	S377G	377	Missense	proximal	2	no	3.509	3.424	EPSD	ICGC;GDSC	1.803	Down-regulation
AGC_RSK_RSKp90_RPS6KA3_ST	Q16821	PPP1R3A	P51812	RPS6KA3	S375	S373F	373	Missense	proximal	-2	no	3.509	3.271	EPSD	ICGC;COSMIC	1.803	Down-regulation
AGC_RSK_RSKp90_RPS6KA3_ST	Q16821	PPP1R3A	P51812	RPS6KA3	S375	F370L	370	Missense	distal	-5	no	3.509	3.612	EPSD	ICGC;COSMIC	1.803	Up-regulation
AGC_RSK_RSKp90_RPS6KA3_ST	Q16821	PPP1R3A	P51812	RPS6KA3	S375	L369V	369	Missense	distal	-6	no	3.509	3.498	EPSD	ICGC	1.803	Down-regulation
AGC_RSK_RSKp90_RPS6KA3_ST	Q16821	PPP1R3A	P51812	RPS6KA3	S375	S375F	375	Missense	central	0	yes	3.509	0.000	EPSD	ICGC;COSMIC	1.803	Loss
AGC_RSK_RSKp90_RPS6KA3_ST	Q16821	PPP1R3A	P51812	RPS6KA3	S377	S379L	379	Missense	proximal	2	no	2.147	2.040	EPSD	ICGC;COSMIC	1.803	Down-regulation
AGC_RSK_RSKp90_RPS6KA3_ST	Q16821	PPP1R3A	P51812	RPS6KA3	S377	S377G	377	Missense	central	0	yes	2.147	0.000	EPSD	ICGC;GDSC	1.803	Loss
AGC_RSK_RSKp90_RPS6KA3_ST	Q16821	PPP1R3A	P51812	RPS6KA3	S377	S373F	373	Missense	distal	-4	no	2.147	2.004	EPSD	ICGC;COSMIC	1.803	Down-regulation
AGC_RSK_RSKp90_RPS6KA3_ST	Q16821	PPP1R3A	P51812	RPS6KA3	S377	F370L	370	Missense	distal	-7	no	2.147	2.141	EPSD	ICGC;COSMIC	1.803	Down-regulation
AGC_RSK_RSKp90_RPS6KA3_ST	Q16821	PPP1R3A	P51812	RPS6KA3	S377	S375F	375	Missense	proximal	-2	no	2.147	1.909	EPSD	ICGC;COSMIC	1.803	Down-regulation
AGC_RSK_RSKp90_RPS6KA3_ST	Q16821	PPP1R3A	P51812	RPS6KA3	S584	V581L	581	Missense	distal	-3	no	1.379	1.972	EPSD	ICGC	1.803	Gain
AGC_RSK_RSKp90_RPS6KA3_ST	Q16821	PPP1R3A	P51812	RPS6KA3	S1033	G1030R	1030	Missense	distal	-3	no	1.345	3.727	EPSD	ICGC	1.803	Gain
AGC_RSK_RSKp90_RPS6KA3_ST	P18848	ATF4	P51812	RPS6KA3	S74	S71P	71	Missense	distal	-3	no	1.839	1.732	EPSD	ICGC	1.803	Loss
AGC_RSK_RSKp90_RPS6KA3_ST	P18848	ATF4	P51812	RPS6KA3	S74	S69R	69	Missense	distal	-5	no	1.839	2.156	EPSD	ICGC	1.803	Up-regulation
AGC_RSK_RSKp90_RPS6KA3_ST	P18848	ATF4	P51812	RPS6KA3	S245	R244M	244	Missense	proximal	-1	no	1.951	1.891	PhosphoSitePlus	ICGC;COSMIC	1.803	Down-regulation
AGC_RSK_RSKp90_RPS6KA3_ST	P18848	ATF4	P51812	RPS6KA3	S248	R244M	244	Missense	distal	-4	no	2.295	2.126	EPSD	ICGC;COSMIC	1.803	Down-regulation
AGC_RSK_RSKp90_RPS6KA3_ST	P18848	ATF4	P51812	RPS6KA3	S326	A324V	324	Missense	proximal	-2	no	3.725	3.554	EPSD	ICGC;COSMIC;GDSC	1.803	Down-regulation
AGC_RSK_RSKp90_RPS6KA3_ST	P32314	FOXN2	P51812	RPS6KA3	T15	G17A	17	Missense	proximal	2	no	1.918	1.944	EPSD	ICGC	1.803	Up-regulation
AGC_RSK_RSKp90_RPS6KA3_ST	P40763	STAT3	P51812	RPS6KA3	S599	A596D	596	Missense	distal	-3	no	1.954	1.494	EPSD	ICGC	1.803	Loss
AGC_RSK_RSKp90_RPS6KA3_ST	P40763	STAT3	P51812	RPS6KA3	S599	S599R	599	Missense	central	0	yes	1.954	0.000	EPSD	ICGC	1.803	Loss
AGC_RSK_RSKp90_RPS6KA3_ST	P40763	STAT3	P51812	RPS6KA3	S599	A596T	596	Missense	distal	-3	no	1.954	1.626	EPSD	ICGC;COSMIC;CCLE	1.803	Loss
AGC_RSK_RSKp90_RPS6KA3_ST	P40763	STAT3	P51812	RPS6KA3	S599	I597M	597	Missense	proximal	-2	no	1.954	1.994	EPSD	ICGC;COSMIC	1.803	Up-regulation
AGC_RSK_RSKp90_RPS6KA3_ST	P40763	STAT3	P51812	RPS6KA3	S599	E594K	594	Missense	distal	-5	no	1.954	2.037	EPSD	ICGC;COSMIC	1.803	Up-regulation
AGC_RSK_RSKp90_RPS6KA3_ST	P40763	STAT3	P51812	RPS6KA3	S599	R593W	593	Missense	distal	-6	no	1.954	1.874	EPSD	ICGC;COSMIC	1.803	Down-regulation
AGC_RSK_RSKp90_RPS6KA3_ST	P40763	STAT3	P51812	RPS6KA3	S691	P689T	689	Missense	proximal	-2	no	3.562	3.481	EPSD	ICGC	1.803	Down-regulation
AGC_RSK_RSKp90_RPS6KA3_ST	P40763	STAT3	P51812	RPS6KA3	S691	S691C	691	Missense	central	0	yes	3.562	0.000	EPSD	ICGC;COSMIC	1.803	Loss
AGC_RSK_RSKp90_RPS6KA3_ST	P40763	STAT3	P51812	RPS6KA3	S691	R688W	688	Missense	distal	-3	no	3.562	1.020	EPSD	ICGC;COSMIC;GDSC;CCLE	1.803	Loss
AGC_RSK_RSKp90_RPS6KA3_ST	P40763	STAT3	P51812	RPS6KA3	S727	L724P	724	Missense	distal	-3	no	2.103	2.220	PhosphoSitePlus	ICGC;COSMIC	1.803	Up-regulation
AGC_RSK_RSKp90_RPS6KA3_ST	P40763	STAT3	P51812	RPS6KA3	S727	S727P	727	Missense	central	0	yes	2.103	0.000	PhosphoSitePlus	ICGC	1.803	Loss
AGC_RSK_RSKp90_RPS6KA3_ST	P40763	STAT3	P51812	RPS6KA3	S727	L734S	734	Missense	distal	7	no	2.103	2.058	PhosphoSitePlus	ICGC;COSMIC	1.803	Down-regulation
AGC_RSK_RSKp90_RPS6KA3_ST	P11362	FGFR1	P51812	RPS6KA3	T428	R424C	424	Missense	distal	-4	no	2.143	1.943	EPSD	ICGC;COSMIC	1.803	Down-regulation
AGC_RSK_RSKp90_RPS6KA3_ST	P11362	FGFR1	P51812	RPS6KA3	T428	Q426K	426	Missense	proximal	-2	no	2.143	2.248	EPSD	ICGC	1.803	Up-regulation
AGC_RSK_RSKp90_RPS6KA3_ST	P11362	FGFR1	P51812	RPS6KA3	T428	P422T	422	Missense	distal	-6	no	2.143	2.125	EPSD	ICGC;COSMIC	1.803	Down-regulation
AGC_RSK_RSKp90_RPS6KA3_ST	P11362	FGFR1	P51812	RPS6KA3	T428	S434F	434	Missense	distal	6	no	2.143	2.074	EPSD	ICGC;COSMIC	1.803	Down-regulation
AGC_RSK_RSKp90_RPS6KA3_ST	P11362	FGFR1	P51812	RPS6KA3	T428	I421T	421	Missense	distal	-7	no	2.143	2.148	EPSD	ICGC	1.803	Up-regulation
AGC_RSK_RSKp90_RPS6KA3_ST	P11362	FGFR1	P51812	RPS6KA3	S433	S434F	434	Missense	proximal	1	no	1.758	1.842	EPSD	ICGC;COSMIC	1.803	Gain
AGC_RSK_RSKp90_RPS6KA3_ST	P11362	FGFR1	P51812	RPS6KA3	S439	S434F	434	Missense	distal	-5	no	1.931	1.798	EPSD	ICGC;COSMIC	1.803	Loss
AGC_RSK_RSKp90_RPS6KA3_ST	P16949	STMN1	P51812	RPS6KA3	S63	S63F	63	Missense	central	0	yes	4.110	0.000	EPSD	ICGC;COSMIC	1.803	Loss
AGC_RSK_RSKp90_RPS6KA3_ST	P16949	STMN1	P51812	RPS6KA3	S139	S139C	139	Missense	central	0	yes	1.844	0.000	EPSD	ICGC;COSMIC	1.803	Loss
AGC_RSK_RSKp90_RPS6KA3_ST	P16949	STMN1	P51812	RPS6KA3	S139	V133A	133	Missense	distal	-6	no	1.844	1.878	EPSD	ICGC;COSMIC;GDSC;CCLE	1.803	Up-regulation
AGC_RSK_RSKp90_RPS6KA3_ST	P16949	STMN1	P51812	RPS6KA3	S139	R134Q	134	Missense	distal	-5	no	1.844	1.482	EPSD	ICGC;COSMIC	1.803	Loss
AGC_RSK_RSKp90_RPS6KA3_ST	P16949	STMN1	P51812	RPS6KA3	S139	D144E	144	Missense	distal	5	no	1.844	1.822	EPSD	ICGC	1.803	Down-regulation
AGC_RSK_RSKp90_RPS6KA3_ST	P16949	STMN1	P51812	RPS6KA3	S139	A143D	143	Missense	distal	4	no	1.844	1.878	EPSD	ICGC;COSMIC	1.803	Up-regulation
AGC_RSK_RSKp90_RPS6KA3_ST	P16949	STMN1	P51812	RPS6KA3	S139	T146N	146	Missense	distal	7	no	1.844	1.826	EPSD	ICGC;COSMIC	1.803	Down-regulation
AGC_RSK_RSKp90_RPS6KA3_ST	P29317	EPHA2	P51812	RPS6KA3	S433	S433N	433	Missense	central	0	yes	1.959	0.000	EPSD	ICGC	1.803	Loss
AGC_RSK_RSKp90_RPS6KA3_ST	P29317	EPHA2	P51812	RPS6KA3	S433	S426R	426	Missense	distal	-7	no	1.959	1.950	EPSD	ICGC;COSMIC	1.803	Down-regulation
AGC_RSK_RSKp90_RPS6KA3_ST	P29317	EPHA2	P51812	RPS6KA3	S433	A430D	430	Missense	distal	-3	no	1.959	1.499	EPSD	ICGC	1.803	Loss
AGC_RSK_RSKp90_RPS6KA3_ST	P29317	EPHA2	P51812	RPS6KA3	S570	V574I	574	Missense	distal	4	no	2.155	2.146	EPSD	ICGC;COSMIC	1.803	Down-regulation
AGC_RSK_RSKp90_RPS6KA3_ST	P29317	EPHA2	P51812	RPS6KA3	S570	A567V	567	Missense	distal	-3	no	2.155	1.442	EPSD	ICGC;COSMIC	1.803	Loss
AGC_RSK_RSKp90_RPS6KA3_ST	P29317	EPHA2	P51812	RPS6KA3	S570	Y575C	575	Missense	distal	5	no	2.155	2.150	EPSD	ICGC	1.803	Down-regulation
AGC_RSK_RSKp90_RPS6KA3_ST	P29317	EPHA2	P51812	RPS6KA3	S636	G630S	630	Missense	distal	-6	no	1.915	1.948	EPSD	ICGC;COSMIC	1.803	Up-regulation
AGC_RSK_RSKp90_RPS6KA3_ST	P29317	EPHA2	P51812	RPS6KA3	S897	R894Q	894	Missense	distal	-3	no	3.710	1.203	PhosphoSitePlus	ICGC;COSMIC	1.803	Loss
AGC_RSK_RSKp90_RPS6KA3_ST	P29317	EPHA2	P51812	RPS6KA3	S899	R894Q	894	Missense	distal	-5	no	2.455	2.092	EPSD	ICGC;COSMIC	1.803	Down-regulation
AGC_RSK_RSKp90_RPS6KA3_ST	P29317	EPHA2	P51812	RPS6KA3	S899	P905S	905	Missense	distal	6	no	2.455	2.490	EPSD	ICGC	1.803	Up-regulation
AGC_RSK_RSKp90_RPS6KA3_ST	P29317	EPHA2	P51812	RPS6KA3	S910	R907C	907	Missense	distal	-3	no	3.449	0.838	EPSD	ICGC;GDSC	1.803	Loss
AGC_RSK_RSKp90_RPS6KA3_ST	P29317	EPHA2	P51812	RPS6KA3	S910	W912C	912	Missense	proximal	2	no	3.449	3.443	EPSD	ICGC;COSMIC	1.803	Down-regulation
AGC_RSK_RSKp90_RPS6KA3_ST	P29317	EPHA2	P51812	RPS6KA3	S910	P905S	905	Missense	distal	-5	no	3.449	3.456	EPSD	ICGC	1.803	Up-regulation
AGC_RSK_RSKp90_RPS6KA3_ST	Q96RK0	CIC	P51812	RPS6KA3	S12	R17C	17	Missense	distal	5	no	1.931	2.033	EPSD	ICGC;COSMIC	1.803	Up-regulation
AGC_RSK_RSKp90_RPS6KA3_ST	Q96RK0	CIC	P51812	RPS6KA3	S12	S12F	12	Missense	central	0	yes	1.931	0.000	EPSD	ICGC;COSMIC	1.803	Loss
AGC_RSK_RSKp90_RPS6KA3_ST	Q96RK0	CIC	P51812	RPS6KA3	S334	A330S	330	Missense	distal	-4	no	2.036	2.076	EPSD	ICGC	1.803	Up-regulation
AGC_RSK_RSKp90_RPS6KA3_ST	Q96RK0	CIC	P51812	RPS6KA3	S334	L341P	341	Missense	distal	7	no	2.036	2.018	EPSD	ICGC	1.803	Down-regulation
AGC_RSK_RSKp90_RPS6KA3_ST	Q96RK0	CIC	P51812	RPS6KA3	S334	R340Q	340	Missense	distal	6	no	2.036	1.980	EPSD	ICGC;COSMIC	1.803	Down-regulation
AGC_RSK_RSKp90_RPS6KA3_ST	Q96RK0	CIC	P51812	RPS6KA3	S334	S333N	333	Missense	proximal	-1	no	2.036	2.008	EPSD	ICGC	1.803	Down-regulation
AGC_RSK_RSKp90_RPS6KA3_ST	Q96RK0	CIC	P51812	RPS6KA3	S334	C336R	336	Missense	proximal	2	no	2.036	2.145	EPSD	ICGC	1.803	Up-regulation
AGC_RSK_RSKp90_RPS6KA3_ST	Q96RK0	CIC	P51812	RPS6KA3	T343	L341P	341	Missense	proximal	-2	no	2.613	2.650	EPSD	ICGC	1.803	Up-regulation
AGC_RSK_RSKp90_RPS6KA3_ST	Q96RK0	CIC	P51812	RPS6KA3	T343	R340Q	340	Missense	distal	-3	no	2.613	0.107	EPSD	ICGC;COSMIC	1.803	Loss
AGC_RSK_RSKp90_RPS6KA3_ST	Q96RK0	CIC	P51812	RPS6KA3	T343	C336R	336	Missense	distal	-7	no	2.613	2.585	EPSD	ICGC	1.803	Down-regulation
AGC_RSK_RSKp90_RPS6KA3_ST	Q96RK0	CIC	P51812	RPS6KA3	S424	P417R	417	Missense	distal	-7	no	1.837	1.817	EPSD	ICGC	1.803	Down-regulation
AGC_RSK_RSKp90_RPS6KA3_ST	Q96RK0	CIC	P51812	RPS6KA3	S424	R428L	428	Missense	distal	4	no	1.837	1.904	EPSD	ICGC	1.803	Up-regulation
AGC_RSK_RSKp90_RPS6KA3_ST	Q96RK0	CIC	P51812	RPS6KA3	S424	A429S	429	Missense	distal	5	no	1.837	1.811	EPSD	ICGC	1.803	Down-regulation
AGC_RSK_RSKp90_RPS6KA3_ST	Q96RK0	CIC	P51812	RPS6KA3	S424	A423S	423	Missense	proximal	-1	no	1.837	1.856	EPSD	ICGC	1.803	Up-regulation
AGC_RSK_RSKp90_RPS6KA3_ST	Q96RK0	CIC	P51812	RPS6KA3	S424	S431I	431	Missense	distal	7	no	1.837	1.877	EPSD	ICGC	1.803	Up-regulation
AGC_RSK_RSKp90_RPS6KA3_ST	Q96RK0	CIC	P51812	RPS6KA3	S424	S426P	426	Missense	proximal	2	no	1.837	1.766	EPSD	ICGC;COSMIC	1.803	Loss
AGC_RSK_RSKp90_RPS6KA3_ST	Q96RK0	CIC	P51812	RPS6KA3	S424	R425C	425	Missense	proximal	1	no	1.837	1.937	EPSD	ICGC	1.803	Up-regulation
AGC_RSK_RSKp90_RPS6KA3_ST	Q96RK0	CIC	P51812	RPS6KA3	S424	Q427H	427	Missense	distal	3	no	1.837	1.839	EPSD	ICGC;COSMIC	1.803	Up-regulation
AGC_RSK_RSKp90_RPS6KA3_ST	Q96RK0	CIC	P51812	RPS6KA3	S424	S431N	431	Missense	distal	7	no	1.837	1.867	EPSD	ICGC;COSMIC	1.803	Up-regulation
AGC_RSK_RSKp90_RPS6KA3_ST	Q96RK0	CIC	P51812	RPS6KA3	S426	R428L	428	Missense	proximal	2	no	1.932	1.818	EPSD	ICGC	1.803	Down-regulation
AGC_RSK_RSKp90_RPS6KA3_ST	Q96RK0	CIC	P51812	RPS6KA3	S426	A429S	429	Missense	distal	3	no	1.932	1.928	EPSD	ICGC	1.803	Down-regulation
AGC_RSK_RSKp90_RPS6KA3_ST	Q96RK0	CIC	P51812	RPS6KA3	S426	D433Y	433	Missense	distal	7	no	1.932	1.936	EPSD	ICGC	1.803	Up-regulation
AGC_RSK_RSKp90_RPS6KA3_ST	Q96RK0	CIC	P51812	RPS6KA3	S426	A423S	423	Missense	distal	-3	no	1.932	2.036	EPSD	ICGC	1.803	Up-regulation
AGC_RSK_RSKp90_RPS6KA3_ST	Q96RK0	CIC	P51812	RPS6KA3	S426	S431I	431	Missense	distal	5	no	1.932	1.993	EPSD	ICGC	1.803	Up-regulation
AGC_RSK_RSKp90_RPS6KA3_ST	Q96RK0	CIC	P51812	RPS6KA3	S426	S426P	426	Missense	central	0	yes	1.932	0.000	EPSD	ICGC;COSMIC	1.803	Loss
AGC_RSK_RSKp90_RPS6KA3_ST	Q96RK0	CIC	P51812	RPS6KA3	S426	R425C	425	Missense	proximal	-1	no	1.932	1.858	EPSD	ICGC	1.803	Down-regulation
AGC_RSK_RSKp90_RPS6KA3_ST	Q96RK0	CIC	P51812	RPS6KA3	S426	Q427H	427	Missense	proximal	1	no	1.932	1.952	EPSD	ICGC;COSMIC	1.803	Up-regulation
AGC_RSK_RSKp90_RPS6KA3_ST	Q96RK0	CIC	P51812	RPS6KA3	S426	S431N	431	Missense	distal	5	no	1.932	1.978	EPSD	ICGC;COSMIC	1.803	Up-regulation
AGC_RSK_RSKp90_RPS6KA3_ST	Q96RK0	CIC	P51812	RPS6KA3	S431	R428L	428	Missense	distal	-3	no	3.621	1.390	EPSD	ICGC	1.803	Loss
AGC_RSK_RSKp90_RPS6KA3_ST	Q96RK0	CIC	P51812	RPS6KA3	S431	A429S	429	Missense	proximal	-2	no	3.621	3.658	EPSD	ICGC	1.803	Up-regulation
AGC_RSK_RSKp90_RPS6KA3_ST	Q96RK0	CIC	P51812	RPS6KA3	S431	D433Y	433	Missense	proximal	2	no	3.621	3.619	EPSD	ICGC	1.803	Down-regulation
AGC_RSK_RSKp90_RPS6KA3_ST	Q96RK0	CIC	P51812	RPS6KA3	S431	S431I	431	Missense	central	0	yes	3.621	0.000	EPSD	ICGC	1.803	Loss
AGC_RSK_RSKp90_RPS6KA3_ST	Q96RK0	CIC	P51812	RPS6KA3	S431	S426P	426	Missense	distal	-5	no	3.621	3.614	EPSD	ICGC;COSMIC	1.803	Down-regulation
AGC_RSK_RSKp90_RPS6KA3_ST	Q96RK0	CIC	P51812	RPS6KA3	S431	R425C	425	Missense	distal	-6	no	3.621	3.534	EPSD	ICGC	1.803	Down-regulation
AGC_RSK_RSKp90_RPS6KA3_ST	Q96RK0	CIC	P51812	RPS6KA3	S431	Q427H	427	Missense	distal	-4	no	3.621	3.599	EPSD	ICGC;COSMIC	1.803	Down-regulation
AGC_RSK_RSKp90_RPS6KA3_ST	Q96RK0	CIC	P51812	RPS6KA3	S431	S431N	431	Missense	central	0	yes	3.621	0.000	EPSD	ICGC;COSMIC	1.803	Loss
AGC_RSK_RSKp90_RPS6KA3_ST	Q96RK0	CIC	P51812	RPS6KA3	S431	T435M	435	Missense	distal	4	no	3.621	3.593	EPSD	ICGC;COSMIC	1.803	Down-regulation
AGC_RSK_RSKp90_RPS6KA3_ST	Q96RK0	CIC	P51812	RPS6KA3	S605	F598I	598	Missense	distal	-7	no	3.884	3.875	EPSD	ICGC;COSMIC	1.803	Down-regulation
AGC_RSK_RSKp90_RPS6KA3_ST	Q96RK0	CIC	P51812	RPS6KA3	S605	R602I	602	Missense	distal	-3	no	3.884	1.417	EPSD	ICGC;COSMIC	1.803	Loss
AGC_RSK_RSKp90_RPS6KA3_ST	Q96RK0	CIC	P51812	RPS6KA3	S649	A652T	652	Missense	distal	3	no	3.204	3.208	EPSD	ICGC;COSMIC	1.803	Up-regulation
AGC_RSK_RSKp90_RPS6KA3_ST	Q96RK0	CIC	P51812	RPS6KA3	S649	P651L	651	Missense	proximal	2	no	3.204	3.168	EPSD	ICGC	1.803	Down-regulation
AGC_RSK_RSKp90_RPS6KA3_ST	Q96RK0	CIC	P51812	RPS6KA3	S739	S734L	734	Missense	distal	-5	no	1.976	1.946	EPSD	ICGC;COSMIC;GDSC	1.803	Down-regulation
AGC_RSK_RSKp90_RPS6KA3_ST	Q96RK0	CIC	P51812	RPS6KA3	S902	Q901H	901	Missense	proximal	-1	no	1.899	1.888	EPSD	ICGC;COSMIC	1.803	Down-regulation
AGC_RSK_RSKp90_RPS6KA3_ST	Q96RK0	CIC	P51812	RPS6KA3	S902	V903F	903	Missense	proximal	1	no	1.899	1.914	EPSD	ICGC	1.803	Up-regulation
AGC_RSK_RSKp90_RPS6KA3_ST	Q96RK0	CIC	P51812	RPS6KA3	S1173	Q1170R	1170	Missense	distal	-3	no	1.566	4.073	EPSD	ICGC	1.803	Gain
AGC_RSK_RSKp90_RPS6KA3_ST	Q96RK0	CIC	P51812	RPS6KA3	T1217	V1213I	1213	Missense	distal	-4	no	1.921	1.952	EPSD	ICGC	1.803	Up-regulation
AGC_RSK_RSKp90_RPS6KA3_ST	Q96RK0	CIC	P51812	RPS6KA3	S1246	W1239C	1239	Missense	distal	-7	no	1.922	1.924	EPSD	ICGC	1.803	Up-regulation
AGC_RSK_RSKp90_RPS6KA3_ST	Q96RK0	CIC	P51812	RPS6KA3	S1351	D1346G	1346	Missense	distal	-5	no	3.301	3.326	EPSD	ICGC	1.803	Up-regulation
AGC_RSK_RSKp90_RPS6KA3_ST	Q96RK0	CIC	P51812	RPS6KA3	S1397	D1399E	1399	Missense	proximal	2	no	4.077	4.100	EPSD	ICGC;COSMIC	1.803	Up-regulation
AGC_RSK_RSKp90_RPS6KA3_ST	Q96RK0	CIC	P51812	RPS6KA3	S1418	R1415C	1415	Missense	distal	-3	no	4.322	1.711	EPSD	ICGC;COSMIC	1.803	Loss
AGC_RSK_RSKp90_RPS6KA3_ST	Q96RK0	CIC	P51812	RPS6KA3	S1419	R1415C	1415	Missense	distal	-4	no	4.181	3.981	EPSD	ICGC;COSMIC	1.803	Down-regulation
AGC_RSK_RSKp90_RPS6KA3_ST	Q96RK0	CIC	P51812	RPS6KA3	S1421	R1415C	1415	Missense	distal	-6	no	2.094	2.007	EPSD	ICGC;COSMIC	1.803	Down-regulation
AGC_RSK_RSKp90_RPS6KA3_ST	Q96RK0	CIC	P51812	RPS6KA3	S1422	R1415C	1415	Missense	distal	-7	no	1.966	1.993	EPSD	ICGC;COSMIC	1.803	Up-regulation
AGC_RSK_RSKp90_RPS6KA3_ST	P25963	NFKBIA	P51812	RPS6KA3	S32	R29S	29	Missense	distal	-3	no	3.469	1.461	PhosphoSitePlus	ICGC	1.803	Loss
AGC_RSK_RSKp90_RPS6KA3_ST	P25963	NFKBIA	P51812	RPS6KA3	S32	D31G	31	Missense	proximal	-1	no	3.469	3.474	PhosphoSitePlus	ICGC;COSMIC	1.803	Up-regulation
AGC_RSK_RSKp90_RPS6KA3_ST	P25963	NFKBIA	P51812	RPS6KA3	S32	K38T	38	Missense	distal	6	no	3.469	3.431	PhosphoSitePlus	ICGC	1.803	Down-regulation
AGC_RSK_RSKp90_RPS6KA3_ST	P05198	EIF2S1	P51812	RPS6KA3	S91	D84Y	84	Missense	distal	-7	no	3.952	3.954	EPSD	ICGC;COSMIC	1.803	Up-regulation
AGC_RSK_RSKp90_RPS6KA3_ST	P05198	EIF2S1	P51812	RPS6KA3	T185	R183H	183	Missense	proximal	-2	no	2.237	1.681	EPSD	ICGC;COSMIC	1.803	Loss
AGC_RSK_RSKp90_RPS6KA3_ST	P05198	EIF2S1	P51812	RPS6KA3	T185	R182G	182	Missense	distal	-3	no	2.237	-0.145	EPSD	ICGC	1.803	Loss
AGC_RSK_RSKp90_RPS6KA3_ST	P05198	EIF2S1	P51812	RPS6KA3	T185	A188S	188	Missense	distal	3	no	2.237	2.233	EPSD	ICGC	1.803	Down-regulation
AGC_RSK_RSKp90_RPS6KA3_ST	P49840	GSK3A	P51812	RPS6KA3	S97	D96E	96	Missense	proximal	-1	no	1.974	1.984	EPSD	ICGC;COSMIC	1.803	Up-regulation
AGC_RSK_RSKp90_RPS6KA3_ST	P49840	GSK3A	P51812	RPS6KA3	S97	R95G	95	Missense	proximal	-2	no	1.974	1.441	EPSD	ICGC;COSMIC	1.803	Loss
AGC_RSK_RSKp90_RPS6KA3_ST	P49840	GSK3A	P51812	RPS6KA3	S97	G98R	98	Missense	proximal	1	no	1.974	1.875	EPSD	ICGC	1.803	Down-regulation
AGC_RSK_RSKp90_RPS6KA3_ST	P49840	GSK3A	P51812	RPS6KA3	S97	V103A	103	Missense	distal	6	no	1.974	2.008	EPSD	ICGC;COSMIC	1.803	Up-regulation
AGC_RSK_RSKp90_RPS6KA3_ST	P49840	GSK3A	P51812	RPS6KA3	T101	G98R	98	Missense	distal	-3	no	-0.099	2.282	EPSD	ICGC	1.803	Gain
AGC_RSK_RSKp90_RPS6KA3_ST	O14649	KCNK3	P51812	RPS6KA3	S334	D332G	332	Missense	proximal	-2	no	3.578	3.618	EPSD	ICGC;COSMIC	1.803	Up-regulation
AGC_RSK_RSKp90_RPS6KA3_ST	O14649	KCNK3	P51812	RPS6KA3	S334	T338K	338	Missense	distal	4	no	3.578	3.529	EPSD	ICGC	1.803	Down-regulation
AGC_RSK_RSKp90_RPS6KA3_ST	O14649	KCNK3	P51812	RPS6KA3	S372	S375F	375	Missense	distal	3	no	2.159	2.169	EPSD	ICGC	1.803	Up-regulation
AGC_RSK_RSKp90_RPS6KA3_ST	O14649	KCNK3	P51812	RPS6KA3	S373	S375F	375	Missense	proximal	2	no	2.219	2.087	EPSD	ICGC	1.803	Down-regulation
CK1_TTBK_TTBK2_ST	Q7L0J3	SV2A	Q6IQ55	TTBK2	S42	S45L	45	Missense	distal	3	no	7.526	7.564	EPSD;PhosphoSitePlus	ICGC;COSMIC	3.341	Up-regulation
CK1_TTBK_TTBK2_ST	Q7L0J3	SV2A	Q6IQ55	TTBK2	S42	S42F	42	Missense	central	0	yes	7.526	0.000	EPSD;PhosphoSitePlus	ICGC;COSMIC	3.341	Loss
CK1_TTBK_TTBK2_ST	Q7L0J3	SV2A	Q6IQ55	TTBK2	S45	E52D	52	Missense	distal	7	no	7.586	7.605	EPSD;PhosphoSitePlus	ICGC;COSMIC;CCLE	3.341	Up-regulation
CK1_TTBK_TTBK2_ST	Q7L0J3	SV2A	Q6IQ55	TTBK2	S45	S45L	45	Missense	central	0	yes	7.586	0.000	EPSD;PhosphoSitePlus	ICGC;COSMIC	3.341	Loss
CK1_TTBK_TTBK2_ST	Q7L0J3	SV2A	Q6IQ55	TTBK2	S45	S42F	42	Missense	distal	-3	no	7.586	7.629	EPSD;PhosphoSitePlus	ICGC;COSMIC	3.341	Up-regulation
CK1_TTBK_TTBK2_ST	Q7L0J3	SV2A	Q6IQ55	TTBK2	S47	E52D	52	Missense	distal	5	no	7.658	6.576	PhosphoSitePlus;EPSD	ICGC;COSMIC;CCLE	3.341	Down-regulation
CK1_TTBK_TTBK2_ST	Q7L0J3	SV2A	Q6IQ55	TTBK2	S47	S45L	45	Missense	proximal	-2	no	7.658	7.704	PhosphoSitePlus;EPSD	ICGC;COSMIC	3.341	Up-regulation
CK1_TTBK_TTBK2_ST	Q7L0J3	SV2A	Q6IQ55	TTBK2	S47	S42F	42	Missense	distal	-5	no	7.658	7.104	PhosphoSitePlus;EPSD	ICGC;COSMIC	3.341	Down-regulation
CK1_TTBK_TTBK2_ST	Q7L0J3	SV2A	Q6IQ55	TTBK2	S482	V486M	486	Missense	distal	4	no	3.525	3.444	EPSD	ICGC;COSMIC	3.341	Down-regulation
CK1_TTBK_TTBK2_ST	Q7L0J3	SV2A	Q6IQ55	TTBK2	S482	G489W	489	Missense	distal	7	no	3.525	3.512	EPSD	ICGC;COSMIC	3.341	Down-regulation
CK1_TTBK_TTBK2_ST	O00139	KIF2A	Q6IQ55	TTBK2	S135	Q131K	131	Missense	distal	-4	no	6.777	6.790	PhosphoSitePlus	ICGC;COSMIC	3.341	Up-regulation
CK1_TTBK_TTBK2_ST	O00139	KIF2A	Q6IQ55	TTBK2	S604	E601D	601	Missense	distal	-3	no	3.853	3.889	EPSD	ICGC	3.341	Up-regulation
TK_Tec_BTK_Y	P16885	PLCG2	Q06187	BTK	Y753	D748Y	748	Missense	distal	-5	no	3.510	3.317	PhosphoSitePlus;EPSD	ICGC;COSMIC	1.787	Down-regulation
TK_Tec_BTK_Y	P16885	PLCG2	Q06187	BTK	Y759	P762H	762	Missense	distal	3	no	3.275	3.204	EPSD;PhosphoSitePlus	ICGC;COSMIC	1.787	Down-regulation
TK_Tec_BTK_Y	P16885	PLCG2	Q06187	BTK	Y1217	N1222K	1222	Missense	distal	5	no	3.342	3.273	EPSD	ICGC;COSMIC	1.787	Down-regulation
TK_Tec_BTK_Y	P16885	PLCG2	Q06187	BTK	Y1217	R1224C	1224	Missense	distal	7	no	3.342	3.234	EPSD	ICGC;COSMIC	1.787	Down-regulation
TK_Tec_BTK_Y	P16885	PLCG2	Q06187	BTK	Y1217	N1211K	1211	Missense	distal	-6	no	3.342	3.401	EPSD	ICGC;COSMIC	1.787	Up-regulation
TK_Tec_BTK_Y	P58753	TIRAP	Q06187	BTK	Y106	A100T	100	Missense	distal	-6	no	2.946	2.866	PhosphoSitePlus;EPSD	ICGC;COSMIC	1.787	Down-regulation
TK_Tec_BTK_Y	P58753	TIRAP	Q06187	BTK	Y187	S180L	180	Missense	distal	-7	no	3.246	3.820	EPSD;PhosphoSitePlus	ICGC;COSMIC	1.787	Up-regulation
TK_Tec_BTK_Y	P58753	TIRAP	Q06187	BTK	Y187	S183I	183	Missense	distal	-4	no	3.246	3.247	EPSD;PhosphoSitePlus	ICGC;COSMIC	1.787	Up-regulation
TK_Tec_BTK_Y	P58753	TIRAP	Q06187	BTK	Y187	E190D	190	Missense	distal	3	no	3.246	3.178	EPSD;PhosphoSitePlus	ICGC	1.787	Down-regulation
TK_Tec_BTK_Y	P58753	TIRAP	Q06187	BTK	Y187	G181V	181	Missense	distal	-6	no	3.246	3.250	EPSD;PhosphoSitePlus	ICGC	1.787	Up-regulation
TK_Tec_BTK_Y	P58753	TIRAP	Q06187	BTK	Y187	P188Q	188	Missense	proximal	1	no	3.246	3.005	EPSD;PhosphoSitePlus	ICGC;COSMIC	1.787	Down-regulation
TK_Tec_BTK_Y	Q06187	BTK	Q06187	BTK	Y223	M228I	228	Missense	distal	5	no	3.703	3.829	PhosphoSitePlus;EPSD	ICGC;COSMIC	1.787	Up-regulation
TK_Tec_BTK_Y	Q06187	BTK	Q06187	BTK	Y223	A221D	221	Missense	proximal	-2	no	3.703	3.745	PhosphoSitePlus;EPSD	ICGC	1.787	Up-regulation
TK_Tec_BTK_Y	Q06187	BTK	Q06187	BTK	Y223	M228T	228	Missense	distal	5	no	3.703	3.728	PhosphoSitePlus;EPSD	ICGC;COSMIC	1.787	Up-regulation
TK_Tec_BTK_Y	Q06187	BTK	Q06187	BTK	Y241	R236Q	236	Missense	distal	-5	no	1.825	1.992	EPSD	ICGC;COSMIC	1.787	Up-regulation
TK_Tec_BTK_Y	Q06187	BTK	Q06187	BTK	Y241	Y241D	241	Missense	central	0	yes	1.825	0.000	EPSD	ICGC;COSMIC	1.787	Loss
TK_Tec_BTK_Y	Q06187	BTK	Q06187	BTK	Y241	F242Y	242	Missense	proximal	1	no	1.825	1.959	EPSD	ICGC;COSMIC	1.787	Up-regulation
TK_Tec_BTK_Y	Q06187	BTK	Q06187	BTK	Y241	L244F	244	Missense	distal	3	no	1.825	1.832	EPSD	ICGC;COSMIC	1.787	Up-regulation
TK_Tec_BTK_Y	Q06187	BTK	Q06187	BTK	Y551	K558T	558	Missense	distal	7	no	2.892	2.807	EPSD;PhosphoSitePlus	ICGC	1.787	Down-regulation
TK_Tec_BTK_Y	Q08881	ITK	Q06187	BTK	Y198	R193Q	193	Missense	distal	-5	no	1.647	1.814	EPSD	ICGC;COSMIC	1.787	Gain
TK_Tec_BTK_Y	Q08881	ITK	Q06187	BTK	Y336	R335L	335	Missense	proximal	-1	no	1.313	2.432	EPSD	ICGC;COSMIC	1.787	Gain
TK_Tec_BTK_Y	P51813	BMX	Q06187	BTK	Y216	K221N	221	Missense	distal	5	no	3.101	3.170	PhosphoSitePlus	ICGC;COSMIC	1.787	Up-regulation
TK_Tec_BTK_Y	P51813	BMX	Q06187	BTK	Y216	S212R	212	Missense	distal	-4	no	3.101	3.119	PhosphoSitePlus	ICGC;COSMIC	1.787	Up-regulation
TK_Tec_BTK_Y	P51813	BMX	Q06187	BTK	Y224	K221N	221	Missense	distal	-3	no	3.767	3.720	EPSD	ICGC;COSMIC	1.787	Down-regulation
TK_Tec_BTK_Y	P51813	BMX	Q06187	BTK	Y224	G225S	225	Missense	proximal	1	no	3.767	3.681	EPSD	ICGC;COSMIC	1.787	Down-regulation
TK_Tec_BTK_Y	Q9UJV9	DDX41	Q06187	BTK	Y414	V412A	412	Missense	proximal	-2	no	3.037	2.893	PhosphoSitePlus	ICGC;COSMIC	1.787	Down-regulation
TK_Tec_BTK_Y	Q9UJV9	DDX41	Q06187	BTK	Y414	E418D	418	Missense	distal	4	no	3.037	3.067	PhosphoSitePlus	ICGC;COSMIC	1.787	Up-regulation
TK_Tec_BTK_Y	Q9UJV9	DDX41	Q06187	BTK	Y414	K416N	416	Missense	proximal	2	no	3.037	2.994	PhosphoSitePlus	ICGC	1.787	Down-regulation
TK_Tec_BTK_Y	P42680	TEC	Q06187	BTK	Y519	Q518K	518	Missense	proximal	-1	no	1.782	1.787	EPSD	ICGC;COSMIC	1.787	Gain
TKL_IRAK_IRAK4_ST	Q96FA3	PELI1	Q9NWZ3	IRAK4	S3	H9N	9	Missense	distal	6	no	104.822	152.263	EPSD	ICGC;COSMIC	132.233	Gain
TKL_IRAK_IRAK4_ST	Q96FA3	PELI1	Q9NWZ3	IRAK4	S70	S70C	70	Missense	central	0	yes	171.120	0.000	EPSD;PhosphoSitePlus	ICGC	132.233	Loss
TKL_IRAK_IRAK4_ST	Q96FA3	PELI1	Q9NWZ3	IRAK4	S70	A65D	65	Missense	distal	-5	no	171.120	168.609	EPSD;PhosphoSitePlus	ICGC	132.233	Down-regulation
TKL_IRAK_IRAK4_ST	Q96FA3	PELI1	Q9NWZ3	IRAK4	S70	Q74K	74	Missense	distal	4	no	171.120	172.465	EPSD;PhosphoSitePlus	ICGC;COSMIC	132.233	Up-regulation
TKL_IRAK_IRAK4_ST	Q96FA3	PELI1	Q9NWZ3	IRAK4	S70	A66E	66	Missense	distal	-4	no	171.120	179.484	EPSD;PhosphoSitePlus	ICGC;COSMIC	132.233	Up-regulation
TKL_IRAK_IRAK4_ST	Q96FA3	PELI1	Q9NWZ3	IRAK4	S70	N71K	71	Missense	proximal	1	no	171.120	172.988	EPSD;PhosphoSitePlus	ICGC	132.233	Up-regulation
TKL_IRAK_IRAK4_ST	Q96FA3	PELI1	Q9NWZ3	IRAK4	S70	Q64K	64	Missense	distal	-6	no	171.120	161.280	EPSD;PhosphoSitePlus	ICGC;COSMIC	132.233	Down-regulation
TKL_IRAK_IRAK4_ST	Q96FA3	PELI1	Q9NWZ3	IRAK4	S70	A66T	66	Missense	distal	-4	no	171.120	196.488	EPSD;PhosphoSitePlus	ICGC;COSMIC	132.233	Up-regulation
TKL_IRAK_IRAK4_ST	Q96FA3	PELI1	Q9NWZ3	IRAK4	S70	H75Y	75	Missense	distal	5	no	171.120	187.630	EPSD;PhosphoSitePlus	ICGC;COSMIC	132.233	Up-regulation
TKL_IRAK_IRAK4_ST	Q96FA3	PELI1	Q9NWZ3	IRAK4	S76	S70C	70	Missense	distal	-6	no	244.887	214.997	EPSD;PhosphoSitePlus	ICGC	132.233	Down-regulation
TKL_IRAK_IRAK4_ST	Q96FA3	PELI1	Q9NWZ3	IRAK4	S76	R83Q	83	Missense	distal	7	no	244.887	247.059	EPSD;PhosphoSitePlus	ICGC;COSMIC	132.233	Up-regulation
TKL_IRAK_IRAK4_ST	Q96FA3	PELI1	Q9NWZ3	IRAK4	S76	Q74K	74	Missense	proximal	-2	no	244.887	243.920	EPSD;PhosphoSitePlus	ICGC;COSMIC	132.233	Down-regulation
TKL_IRAK_IRAK4_ST	Q96FA3	PELI1	Q9NWZ3	IRAK4	S76	N71K	71	Missense	distal	-5	no	244.887	249.029	EPSD;PhosphoSitePlus	ICGC	132.233	Up-regulation
TKL_IRAK_IRAK4_ST	Q96FA3	PELI1	Q9NWZ3	IRAK4	S76	H75Y	75	Missense	proximal	-1	no	244.887	244.104	EPSD;PhosphoSitePlus	ICGC;COSMIC	132.233	Down-regulation
TKL_IRAK_IRAK4_ST	Q96FA3	PELI1	Q9NWZ3	IRAK4	S78	R83Q	83	Missense	distal	5	no	173.280	184.623	EPSD;PhosphoSitePlus	ICGC;COSMIC	132.233	Up-regulation
TKL_IRAK_IRAK4_ST	Q96FA3	PELI1	Q9NWZ3	IRAK4	S78	Q74K	74	Missense	distal	-4	no	173.280	171.933	EPSD;PhosphoSitePlus	ICGC;COSMIC	132.233	Down-regulation
TKL_IRAK_IRAK4_ST	Q96FA3	PELI1	Q9NWZ3	IRAK4	S78	N71K	71	Missense	distal	-7	no	173.280	182.210	EPSD;PhosphoSitePlus	ICGC	132.233	Up-regulation
TKL_IRAK_IRAK4_ST	Q96FA3	PELI1	Q9NWZ3	IRAK4	S78	H75Y	75	Missense	distal	-3	no	173.280	171.404	EPSD;PhosphoSitePlus	ICGC;COSMIC	132.233	Down-regulation
TKL_IRAK_IRAK4_ST	Q96FA3	PELI1	Q9NWZ3	IRAK4	T80	R83Q	83	Missense	distal	3	no	189.204	191.846	PhosphoSitePlus;EPSD	ICGC;COSMIC	132.233	Up-regulation
TKL_IRAK_IRAK4_ST	Q96FA3	PELI1	Q9NWZ3	IRAK4	T80	Q74K	74	Missense	distal	-6	no	189.204	179.364	PhosphoSitePlus;EPSD	ICGC;COSMIC	132.233	Down-regulation
TKL_IRAK_IRAK4_ST	Q96FA3	PELI1	Q9NWZ3	IRAK4	T80	H75Y	75	Missense	distal	-5	no	189.204	198.151	PhosphoSitePlus;EPSD	ICGC;COSMIC	132.233	Up-regulation
TKL_IRAK_IRAK4_ST	Q96FA3	PELI1	Q9NWZ3	IRAK4	S82	R83Q	83	Missense	proximal	1	no	173.524	178.870	EPSD;PhosphoSitePlus	ICGC;COSMIC	132.233	Up-regulation
TKL_IRAK_IRAK4_ST	Q96FA3	PELI1	Q9NWZ3	IRAK4	S82	H75Y	75	Missense	distal	-7	no	173.524	185.253	EPSD;PhosphoSitePlus	ICGC;COSMIC	132.233	Up-regulation
TKL_IRAK_IRAK4_ST	Q96FA3	PELI1	Q9NWZ3	IRAK4	T86	R83Q	83	Missense	distal	-3	no	195.317	194.540	EPSD;PhosphoSitePlus	ICGC;COSMIC	132.233	Down-regulation
TKL_IRAK_IRAK4_ST	Q96FA3	PELI1	Q9NWZ3	IRAK4	T127	T127A	127	Missense	central	0	yes	207.540	0.000	EPSD;PhosphoSitePlus	ICGC;COSMIC	132.233	Loss
TKL_IRAK_IRAK4_ST	Q96FA3	PELI1	Q9NWZ3	IRAK4	T288	N287D	287	Missense	proximal	-1	no	161.359	162.388	EPSD;PhosphoSitePlus	ICGC;COSMIC	132.233	Up-regulation
TKL_IRAK_IRAK4_ST	Q96FA3	PELI1	Q9NWZ3	IRAK4	S293	N287D	287	Missense	distal	-6	no	169.983	126.184	EPSD;PhosphoSitePlus	ICGC;COSMIC	132.233	Loss
TKL_IRAK_IRAK4_ST	P51617	IRAK1	Q9NWZ3	IRAK4	T381	G386C	386	Missense	distal	5	no	170.123	171.722	EPSD	ICGC	132.233	Up-regulation
TKL_IRAK_IRAK4_ST	P51617	IRAK1	Q9NWZ3	IRAK4	T387	G386C	386	Missense	proximal	-1	no	205.395	205.537	PhosphoSitePlus;EPSD	ICGC	132.233	Up-regulation
TKL_IRAK_IRAK4_ST	P51617	IRAK1	Q9NWZ3	IRAK4	T512	L518I	518	Missense	distal	6	no	107.314	133.189	EPSD	ICGC;COSMIC	132.233	Gain
TKL_IRAK_IRAK4_ST	Q9NWZ3	IRAK4	Q9NWZ3	IRAK4	T208	A211P	211	Missense	distal	3	no	238.403	236.407	PhosphoSitePlus;EPSD	ICGC;COSMIC	132.233	Down-regulation
TKL_IRAK_IRAK4_ST	Q9NWZ3	IRAK4	Q9NWZ3	IRAK4	T209	A211P	211	Missense	proximal	2	no	179.147	181.472	EPSD;PhosphoSitePlus	ICGC;COSMIC	132.233	Up-regulation
TKL_IRAK_IRAK4_ST	Q9NWZ3	IRAK4	Q9NWZ3	IRAK4	T209	A216T	216	Missense	distal	7	no	179.147	193.027	EPSD;PhosphoSitePlus	ICGC;COSMIC	132.233	Up-regulation
TKL_IRAK_IRAK4_ST	P14598	NCF1	Q9NWZ3	IRAK4	T95	G99S	99	Missense	distal	4	no	128.257	143.863	EPSD	ICGC	132.233	Gain
CK1_TTBK_TTBK1_ST	P10636	MAPT	Q5TCY1	TTBK1	S228	P233H	233	Missense	distal	5	no	11.654	11.728	EPSD	ICGC;COSMIC	7.699	Up-regulation
CK1_TTBK_TTBK1_ST	P10636	MAPT	Q5TCY1	TTBK1	S228	S232F	232	Missense	distal	4	no	11.654	11.294	EPSD	ICGC	7.699	Down-regulation
CK1_TTBK_TTBK1_ST	P10636	MAPT	Q5TCY1	TTBK1	S228	D225N	225	Missense	distal	-3	no	11.654	11.636	EPSD	ICGC	7.699	Down-regulation
CK1_TTBK_TTBK1_ST	P10636	MAPT	Q5TCY1	TTBK1	S228	V224I	224	Missense	distal	-4	no	11.654	11.691	EPSD	ICGC;COSMIC	7.699	Up-regulation
CK1_TTBK_TTBK1_ST	P10636	MAPT	Q5TCY1	TTBK1	S238	P233H	233	Missense	distal	-5	no	11.337	11.159	EPSD	ICGC;COSMIC	7.699	Down-regulation
CK1_TTBK_TTBK1_ST	P10636	MAPT	Q5TCY1	TTBK1	S238	S232F	232	Missense	distal	-6	no	11.337	10.574	EPSD	ICGC	7.699	Down-regulation
CK1_TTBK_TTBK1_ST	P10636	MAPT	Q5TCY1	TTBK1	S238	P239Q	239	Missense	proximal	1	no	11.337	6.659	EPSD	ICGC;COSMIC	7.699	Loss
CK1_TTBK_TTBK1_ST	P10636	MAPT	Q5TCY1	TTBK1	S428	S427F	427	Missense	proximal	-1	no	11.626	11.513	EPSD	ICGC	7.699	Down-regulation
CK1_TTBK_TTBK1_ST	P10636	MAPT	Q5TCY1	TTBK1	S515	G521R	521	Missense	distal	6	no	14.725	14.564	EPSD	ICGC;COSMIC	7.699	Down-regulation
CK1_TTBK_TTBK1_ST	P10636	MAPT	Q5TCY1	TTBK1	S516	G521R	521	Missense	distal	5	no	14.085	14.507	EPSD	ICGC;COSMIC	7.699	Up-regulation
CK1_TTBK_TTBK1_ST	P10636	MAPT	Q5TCY1	TTBK1	S519	G521R	521	Missense	proximal	2	no	19.267	19.343	EPSD	ICGC;COSMIC	7.699	Up-regulation
CK1_TTBK_TTBK1_ST	P10636	MAPT	Q5TCY1	TTBK1	T522	G521R	521	Missense	proximal	-1	no	12.073	12.443	EPSD	ICGC;COSMIC	7.699	Up-regulation
TKL_MLK_ZAK_MAP3K20_ST	O96017	CHEK2	Q9NYL2	MAP3K20	S210	D207H	207	Missense	distal	-3	no	2.499	2.803	EPSD	ICGC;COSMIC	2.674	Gain
TKL_MLK_ZAK_MAP3K20_ST	O96017	CHEK2	Q9NYL2	MAP3K20	T383	S379F	379	Missense	distal	-4	no	2.532	3.103	EPSD	ICGC;COSMIC	2.674	Gain
TKL_MLK_ZAK_MAP3K20_ST	O96017	CHEK2	Q9NYL2	MAP3K20	T383	L380V	380	Missense	distal	-3	no	2.532	2.681	EPSD	ICGC;COSMIC	2.674	Gain
TKL_MLK_ZAK_MAP3K20_ST	O96017	CHEK2	Q9NYL2	MAP3K20	S435	Q433E	433	Missense	proximal	-2	no	3.094	3.106	EPSD	ICGC;COSMIC	2.674	Up-regulation
TKL_MLK_ZAK_MAP3K20_ST	O96017	CHEK2	Q9NYL2	MAP3K20	S435	S428F	428	Missense	distal	-7	no	3.094	2.737	EPSD	ICGC;COSMIC	2.674	Down-regulation
TKL_MLK_ZAK_MAP3K20_ST	O96017	CHEK2	Q9NYL2	MAP3K20	S435	H430Y	430	Missense	distal	-5	no	3.094	2.938	EPSD	ICGC;COSMIC	2.674	Down-regulation
TKL_MLK_ZAK_MAP3K20_ST	O96017	CHEK2	Q9NYL2	MAP3K20	T441	F447L	447	Missense	distal	6	no	3.549	3.434	EPSD	ICGC;COSMIC	2.674	Down-regulation
TKL_MLK_ZAK_MAP3K20_ST	O96017	CHEK2	Q9NYL2	MAP3K20	S505	A507V	507	Missense	proximal	2	no	3.271	3.576	EPSD	ICGC	2.674	Up-regulation
TKL_MLK_ZAK_MAP3K20_ST	O96017	CHEK2	Q9NYL2	MAP3K20	S505	P509S	509	Missense	distal	4	no	3.271	3.388	EPSD	ICGC;COSMIC	2.674	Up-regulation
TKL_MLK_ZAK_MAP3K20_ST	O96017	CHEK2	Q9NYL2	MAP3K20	S516	R521W	521	Missense	distal	5	no	2.827	2.710	EPSD	ICGC;COSMIC	2.674	Down-regulation
TKL_MLK_ZAK_MAP3K20_ST	O96017	CHEK2	Q9NYL2	MAP3K20	S516	P509S	509	Missense	distal	-7	no	2.827	3.124	EPSD	ICGC;COSMIC	2.674	Up-regulation
TKL_MLK_ZAK_MAP3K20_ST	O96017	CHEK2	Q9NYL2	MAP3K20	S516	R523L	523	Missense	distal	7	no	2.827	2.854	EPSD	ICGC;COSMIC	2.674	Up-regulation
TKL_MLK_ZAK_MAP3K20_ST	O96017	CHEK2	Q9NYL2	MAP3K20	S518	R521W	521	Missense	distal	3	no	3.168	3.013	EPSD	ICGC;COSMIC	2.674	Down-regulation
TKL_MLK_ZAK_MAP3K20_ST	O96017	CHEK2	Q9NYL2	MAP3K20	S518	R523L	523	Missense	distal	5	no	3.168	3.372	EPSD	ICGC;COSMIC	2.674	Up-regulation
CAMK_CAMKL_NuaK_NUAK1_ST	P38936	CDKN1A	O60285	NUAK1	S31	E28K	28	Missense	distal	-3	no	2.428	4.376	EPSD	ICGC;COSMIC	4.034	Gain
CAMK_CAMKL_NuaK_NUAK1_ST	P38936	CDKN1A	O60285	NUAK1	S130	P131T	131	Missense	proximal	1	no	4.669	4.663	EPSD	ICGC;COSMIC	4.034	Down-regulation
CAMK_CAMKL_NuaK_NUAK1_ST	P38936	CDKN1A	O60285	NUAK1	S130	P131Q	131	Missense	proximal	1	no	4.669	4.700	EPSD	ICGC;COSMIC	4.034	Up-regulation
CAMK_CAMKL_NuaK_NUAK1_ST	P38936	CDKN1A	O60285	NUAK1	S130	G129W	129	Missense	proximal	-1	no	4.669	4.383	EPSD	ICGC;COSMIC	4.034	Down-regulation
CAMK_CAMKL_NuaK_NUAK1_ST	P38936	CDKN1A	O60285	NUAK1	S137	R143L	143	Missense	distal	6	no	5.630	5.612	EPSD	ICGC	4.034	Down-regulation
CAMK_CAMKL_NuaK_NUAK1_ST	P38936	CDKN1A	O60285	NUAK1	S137	R142Q	142	Missense	distal	5	no	5.630	5.438	EPSD	ICGC	4.034	Down-regulation
CAMK_CAMKL_NuaK_NUAK1_ST	P38936	CDKN1A	O60285	NUAK1	S137	R140Q	140	Missense	distal	3	no	5.630	5.642	EPSD	ICGC;COSMIC	4.034	Up-regulation
CAMK_CAMKL_NuaK_NUAK1_ST	P38936	CDKN1A	O60285	NUAK1	S137	P131T	131	Missense	distal	-6	no	5.630	5.439	EPSD	ICGC;COSMIC	4.034	Down-regulation
CAMK_CAMKL_NuaK_NUAK1_ST	P38936	CDKN1A	O60285	NUAK1	S137	P131Q	131	Missense	distal	-6	no	5.630	5.474	EPSD	ICGC;COSMIC	4.034	Down-regulation
CAMK_CAMKL_NuaK_NUAK1_ST	P38936	CDKN1A	O60285	NUAK1	S146	R143L	143	Missense	distal	-3	no	5.858	4.006	PhosphoSitePlus	ICGC	4.034	Loss
CAMK_CAMKL_NuaK_NUAK1_ST	P38936	CDKN1A	O60285	NUAK1	S146	R142Q	142	Missense	distal	-4	no	5.858	5.872	PhosphoSitePlus	ICGC	4.034	Up-regulation
CAMK_CAMKL_NuaK_NUAK1_ST	P38936	CDKN1A	O60285	NUAK1	S146	R140Q	140	Missense	distal	-6	no	5.858	5.710	PhosphoSitePlus	ICGC;COSMIC	4.034	Down-regulation
CAMK_CAMKL_NuaK_NUAK1_ST	P10636	MAPT	O60285	NUAK1	S214	G208C	208	Missense	distal	-6	no	5.065	5.059	EPSD	ICGC;COSMIC	4.034	Down-regulation
CAMK_CAMKL_NuaK_NUAK1_ST	P10636	MAPT	O60285	NUAK1	S214	R211S	211	Missense	distal	-3	no	5.065	3.037	EPSD	ICGC;COSMIC	4.034	Loss
CAMK_CAMKL_NuaK_NUAK1_ST	P10636	MAPT	O60285	NUAK1	S214	G213E	213	Missense	proximal	-1	no	5.065	4.951	EPSD	ICGC;COSMIC	4.034	Down-regulation
CAMK_CAMKL_NuaK_NUAK1_ST	P10636	MAPT	O60285	NUAK1	S228	S232F	232	Missense	distal	4	no	3.770	5.235	EPSD	ICGC	4.034	Gain
CAMK_CAMKL_NuaK_NUAK1_ST	P10636	MAPT	O60285	NUAK1	S369	P363L	363	Missense	distal	-6	no	4.000	4.043	EPSD	ICGC	4.034	Gain
CAMK_CAMKL_NuaK_NUAK1_ST	P10636	MAPT	O60285	NUAK1	S438	Y441H	441	Missense	distal	3	no	4.184	4.192	EPSD	ICGC;COSMIC	4.034	Up-regulation
CAMK_CAMKL_NuaK_NUAK1_ST	O14974	PPP1R12A	O60285	NUAK1	S365	E362K	362	Missense	distal	-3	no	2.091	4.040	EPSD	ICGC;COSMIC	4.034	Gain
CAMK_CAMKL_NuaK_NUAK1_ST	O14974	PPP1R12A	O60285	NUAK1	S432	W436L	436	Missense	distal	4	no	4.000	5.120	EPSD	ICGC;COSMIC	4.034	Gain
CAMK_CAMKL_NuaK_NUAK1_ST	O14974	PPP1R12A	O60285	NUAK1	S472	R469H	469	Missense	distal	-3	no	9.804	7.164	PhosphoSitePlus;EPSD	ICGC;COSMIC	4.034	Down-regulation
CAMK_CAMKL_NuaK_NUAK1_ST	O14974	PPP1R12A	O60285	NUAK1	S472	G466C	466	Missense	distal	-6	no	9.804	9.797	PhosphoSitePlus;EPSD	ICGC;COSMIC	4.034	Down-regulation
CAMK_CAMKL_NuaK_NUAK1_ST	O14974	PPP1R12A	O60285	NUAK1	S472	S478Y	478	Missense	distal	6	no	9.804	9.768	PhosphoSitePlus;EPSD	ICGC;COSMIC	4.034	Down-regulation
CAMK_CAMKL_NuaK_NUAK1_ST	O14974	PPP1R12A	O60285	NUAK1	S541	N540Y	540	Missense	proximal	-1	no	4.998	4.777	EPSD	ICGC;COSMIC	4.034	Down-regulation
CAMK_CAMKL_NuaK_NUAK1_ST	O14974	PPP1R12A	O60285	NUAK1	S541	S542L	542	Missense	proximal	1	no	4.998	5.002	EPSD	ICGC;COSMIC	4.034	Up-regulation
CAMK_CAMKL_NuaK_NUAK1_ST	O14974	PPP1R12A	O60285	NUAK1	S541	L537F	537	Missense	distal	-4	no	4.998	5.014	EPSD	ICGC	4.034	Up-regulation
CAMK_CAMKL_NuaK_NUAK1_ST	O14974	PPP1R12A	O60285	NUAK1	S542	N540Y	540	Missense	proximal	-2	no	4.567	4.736	EPSD	ICGC;COSMIC	4.034	Up-regulation
CAMK_CAMKL_NuaK_NUAK1_ST	O14974	PPP1R12A	O60285	NUAK1	S542	S542L	542	Missense	central	0	yes	4.567	0.000	EPSD	ICGC;COSMIC	4.034	Loss
CAMK_CAMKL_NuaK_NUAK1_ST	O14974	PPP1R12A	O60285	NUAK1	S542	L537F	537	Missense	distal	-5	no	4.567	4.564	EPSD	ICGC	4.034	Down-regulation
CAMK_CAMKL_NuaK_NUAK1_ST	O14974	PPP1R12A	O60285	NUAK1	S610	R612C	612	Missense	proximal	2	no	4.065	3.959	EPSD	ICGC;COSMIC	4.034	Loss
CAMK_CAMKL_NuaK_NUAK1_ST	O14974	PPP1R12A	O60285	NUAK1	S610	E616D	616	Missense	distal	6	no	4.065	4.050	EPSD	ICGC;COSMIC	4.034	Down-regulation
CAMK_CAMKL_NuaK_NUAK1_ST	O14974	PPP1R12A	O60285	NUAK1	S668	R666H	666	Missense	proximal	-2	no	4.184	4.082	EPSD	ICGC;COSMIC	4.034	Down-regulation
CAMK_CAMKL_NuaK_NUAK1_ST	O14974	PPP1R12A	O60285	NUAK1	S668	R666C	666	Missense	proximal	-2	no	4.184	4.253	EPSD	ICGC	4.034	Up-regulation
CAMK_CAMKL_NuaK_NUAK1_ST	O14974	PPP1R12A	O60285	NUAK1	S716	T710A	710	Missense	distal	-6	no	4.110	4.285	EPSD	ICGC;COSMIC	4.034	Up-regulation
CAMK_CAMKL_NuaK_NUAK1_ST	O14974	PPP1R12A	O60285	NUAK1	S862	Q869K	869	Missense	distal	7	no	4.293	4.213	EPSD	ICGC	4.034	Down-regulation
CAMK_CAMKL_NuaK_NUAK1_ST	O14974	PPP1R12A	O60285	NUAK1	S910	R917G	917	Missense	distal	7	no	9.475	9.401	EPSD;PhosphoSitePlus	ICGC;COSMIC	4.034	Down-regulation
CAMK_CAMKL_NuaK_NUAK1_ST	O14974	PPP1R12A	O60285	NUAK1	S910	R907H	907	Missense	distal	-3	no	9.475	6.835	EPSD;PhosphoSitePlus	ICGC;COSMIC	4.034	Down-regulation
CAMK_CAMKL_NuaK_NUAK1_ST	O14974	PPP1R12A	O60285	NUAK1	S910	G909R	909	Missense	proximal	-1	no	9.475	9.341	EPSD;PhosphoSitePlus	ICGC;COSMIC	4.034	Down-regulation
CAMK_CAMKL_NuaK_NUAK1_ST	O14974	PPP1R12A	O60285	NUAK1	S912	G909R	909	Missense	distal	-3	no	2.969	4.249	EPSD	ICGC;COSMIC	4.034	Gain
CAMK_CAMKL_NuaK_NUAK1_ST	O14974	PPP1R12A	O60285	NUAK1	S921	R917G	917	Missense	distal	-4	no	4.692	4.802	EPSD	ICGC;COSMIC	4.034	Up-regulation
CAMK_CAMKL_NuaK_NUAK1_ST	O14974	PPP1R12A	O60285	NUAK1	S921	L924I	924	Missense	distal	3	no	4.692	4.640	EPSD	ICGC	4.034	Down-regulation
CAMK_CAMKL_NuaK_NUAK1_ST	O14974	PPP1R12A	O60285	NUAK1	S929	L924I	924	Missense	distal	-5	no	5.157	5.020	EPSD	ICGC	4.034	Down-regulation
CAMK_CAMKL_NuaK_NUAK1_ST	P55212	CASP6	O60285	NUAK1	S3	G10W	10	Missense	distal	7	no	4.590	4.584	EPSD	ICGC;COSMIC	4.034	Down-regulation
CAMK_CAMKL_NuaK_NUAK1_ST	P04637	TP53	O60285	NUAK1	S15	E11K	11	Missense	distal	-4	no	7.071	6.881	EPSD;PhosphoSitePlus	ICGC;COSMIC	4.034	Down-regulation
CAMK_CAMKL_NuaK_NUAK1_ST	P04637	TP53	O60285	NUAK1	S392	F385L	385	Missense	distal	-7	no	6.382	6.267	PhosphoSitePlus;EPSD	ICGC;COSMIC	4.034	Down-regulation
CAMK_CAMKL_NuaK_NUAK1_ST	O95835	LATS1	O60285	NUAK1	S21	T17N	17	Missense	distal	-4	no	4.364	4.491	EPSD	ICGC	4.034	Up-regulation
CAMK_CAMKL_NuaK_NUAK1_ST	O95835	LATS1	O60285	NUAK1	S216	I220M	220	Missense	distal	4	no	4.999	5.019	EPSD	ICGC;COSMIC	4.034	Up-regulation
CAMK_CAMKL_NuaK_NUAK1_ST	O95835	LATS1	O60285	NUAK1	S596	E592D	592	Missense	distal	-4	no	5.604	5.440	EPSD	ICGC;COSMIC	4.034	Down-regulation
CAMK_CAMKL_NuaK_NUAK1_ST	O95835	LATS1	O60285	NUAK1	S633	S635T	635	Missense	proximal	2	no	4.312	3.982	EPSD	ICGC;COSMIC	4.034	Loss
CAMK_CAMKL_NuaK_NUAK1_ST	O95835	LATS1	O60285	NUAK1	S872	Q870H	870	Missense	proximal	-2	no	4.576	4.389	EPSD	ICGC;COSMIC	4.034	Down-regulation
Other_ULK_ULK_ULK2_ST	O15027	SEC16A	Q8IYT8	ULK2	S112	L114P	114	Missense	proximal	2	no	3.035	3.474	EPSD	ICGC;COSMIC	3.097	Gain
Other_ULK_ULK_ULK2_ST	O15027	SEC16A	Q8IYT8	ULK2	S118	L114P	114	Missense	distal	-4	no	3.778	4.020	EPSD	ICGC;COSMIC	3.097	Up-regulation
Other_ULK_ULK_ULK2_ST	O15027	SEC16A	Q8IYT8	ULK2	S118	P120L	120	Missense	proximal	2	no	3.778	3.338	EPSD	ICGC	3.097	Down-regulation
Other_ULK_ULK_ULK2_ST	O15027	SEC16A	Q8IYT8	ULK2	S122	P120L	120	Missense	proximal	-2	no	3.942	3.955	EPSD	ICGC	3.097	Up-regulation
Other_ULK_ULK_ULK2_ST	O15027	SEC16A	Q8IYT8	ULK2	T337	S342R	342	Missense	distal	5	no	3.733	3.732	EPSD	ICGC;COSMIC	3.097	Down-regulation
Other_ULK_ULK_ULK2_ST	O15027	SEC16A	Q8IYT8	ULK2	S345	S342R	342	Missense	distal	-3	no	2.415	3.511	EPSD	ICGC;COSMIC	3.097	Gain
Other_ULK_ULK_ULK2_ST	O15027	SEC16A	Q8IYT8	ULK2	S346	S342R	342	Missense	distal	-4	no	3.321	3.497	EPSD	ICGC;COSMIC	3.097	Up-regulation
Other_ULK_ULK_ULK2_ST	O15027	SEC16A	Q8IYT8	ULK2	S771	A777T	777	Missense	distal	6	no	3.216	3.210	EPSD	ICGC;COSMIC	3.097	Down-regulation
Other_ULK_ULK_ULK2_ST	O15027	SEC16A	Q8IYT8	ULK2	S779	A777T	777	Missense	proximal	-2	no	3.511	3.540	EPSD	ICGC;COSMIC	3.097	Up-regulation
Other_ULK_ULK_ULK2_ST	O15027	SEC16A	Q8IYT8	ULK2	S1196	Y1202C	1202	Missense	distal	6	no	3.181	3.185	EPSD	ICGC;COSMIC	3.097	Up-regulation
Other_ULK_ULK_ULK2_ST	O15027	SEC16A	Q8IYT8	ULK2	S1199	Y1202C	1202	Missense	distal	3	no	3.161	3.203	EPSD	ICGC;COSMIC	3.097	Up-regulation
Other_ULK_ULK_ULK2_ST	O15027	SEC16A	Q8IYT8	ULK2	S1204	Y1202C	1202	Missense	proximal	-2	no	3.365	3.363	EPSD	ICGC;COSMIC	3.097	Down-regulation
Other_ULK_ULK_ULK2_ST	O15027	SEC16A	Q8IYT8	ULK2	S1236	Y1243C	1243	Missense	distal	7	no	3.523	3.515	EPSD	ICGC;COSMIC	3.097	Down-regulation
Other_ULK_ULK_ULK2_ST	O15027	SEC16A	Q8IYT8	ULK2	S1981	P1976T	1976	Missense	distal	-5	no	3.951	3.979	EPSD	ICGC	3.097	Up-regulation
Other_ULK_ULK_ULK2_ST	A2RUS2	DENND3	Q8IYT8	ULK2	T361	L363P	363	Missense	proximal	2	no	2.994	3.433	EPSD	ICGC;COSMIC	3.097	Gain
Other_ULK_ULK_ULK2_ST	A2RUS2	DENND3	Q8IYT8	ULK2	S368	K374N	374	Missense	distal	6	no	3.130	3.142	EPSD	ICGC	3.097	Up-regulation
Other_ULK_ULK_ULK2_ST	A2RUS2	DENND3	Q8IYT8	ULK2	S368	V373L	373	Missense	distal	5	no	3.130	3.171	EPSD	ICGC	3.097	Up-regulation
Other_ULK_ULK_ULK2_ST	A2RUS2	DENND3	Q8IYT8	ULK2	S368	D372Y	372	Missense	distal	4	no	3.130	3.213	EPSD	ICGC	3.097	Up-regulation
Other_ULK_ULK_ULK2_ST	A2RUS2	DENND3	Q8IYT8	ULK2	S368	L363P	363	Missense	distal	-5	no	3.130	3.139	EPSD	ICGC;COSMIC	3.097	Up-regulation
Other_ULK_ULK_ULK2_ST	A2RUS2	DENND3	Q8IYT8	ULK2	S368	R371M	371	Missense	distal	3	no	3.130	3.101	EPSD	ICGC;COSMIC	3.097	Down-regulation
Other_ULK_ULK_ULK2_ST	A2RUS2	DENND3	Q8IYT8	ULK2	S503	R500T	500	Missense	distal	-3	no	3.204	2.394	EPSD	ICGC;COSMIC	3.097	Loss
Other_ULK_ULK_ULK2_ST	A2RUS2	DENND3	Q8IYT8	ULK2	S503	A504T	504	Missense	proximal	1	no	3.204	3.487	EPSD	ICGC;COSMIC	3.097	Up-regulation
Other_ULK_ULK_ULK2_ST	A2RUS2	DENND3	Q8IYT8	ULK2	S503	V505A	505	Missense	proximal	2	no	3.204	2.918	EPSD	ICGC	3.097	Loss
Other_ULK_ULK_ULK2_ST	A2RUS2	DENND3	Q8IYT8	ULK2	T771	V767F	767	Missense	distal	-4	no	2.683	3.099	EPSD	ICGC	3.097	Gain
Other_PEK_HRI_EIF2AK1_ST	P05198	EIF2S1	Q9BQI3	EIF2AK1	S49	L48V	48	Missense	proximal	-1	no	7.554	7.493	EPSD;PhosphoSitePlus	COSMIC	2.464	Down-regulation
Other_PEK_HRI_EIF2AK1_ST	P05198	EIF2S1	Q9BQI3	EIF2AK1	S49	R55H	55	Missense	distal	6	no	7.554	7.472	EPSD;PhosphoSitePlus	COSMIC	2.464	Down-regulation
Other_PEK_HRI_EIF2AK1_ST	P05198	EIF2S1	Q9BQI3	EIF2AK1	S49	R55C	55	Missense	distal	6	no	7.554	7.571	EPSD;PhosphoSitePlus	COSMIC	2.464	Up-regulation
Other_PEK_HRI_EIF2AK1_ST	P05198	EIF2S1	Q9BQI3	EIF2AK1	S52	L48V	48	Missense	distal	-4	no	8.502	8.498	PhosphoSitePlus;EPSD	COSMIC	2.464	Down-regulation
Other_PEK_HRI_EIF2AK1_ST	P05198	EIF2S1	Q9BQI3	EIF2AK1	S52	R55H	55	Missense	distal	3	no	8.502	8.473	PhosphoSitePlus;EPSD	COSMIC	2.464	Down-regulation
Other_PEK_HRI_EIF2AK1_ST	P05198	EIF2S1	Q9BQI3	EIF2AK1	S52	R55C	55	Missense	distal	3	no	8.502	8.509	PhosphoSitePlus;EPSD	COSMIC	2.464	Up-regulation
Other_PEK_HRI_EIF2AK1_ST	P05198	EIF2S1	Q9BQI3	EIF2AK1	S219	P224L	224	Missense	distal	5	no	2.612	2.567	EPSD	COSMIC	2.464	Down-regulation
AGC_PKC_PKCd_PRKCD_ST	Q9UQL6	HDAC5	Q05655	PRKCD	S24	L20M	20	Missense	distal	-4	no	10.387	10.388	EPSD	COSMIC	7.604	Up-regulation
AGC_PKC_PKCd_PRKCD_ST	Q9UQL6	HDAC5	Q05655	PRKCD	S24	L17F	17	Missense	distal	-7	no	10.387	10.388	EPSD	COSMIC	7.604	Up-regulation
AGC_PKC_PKCd_PRKCD_ST	Q9UQL6	HDAC5	Q05655	PRKCD	S24	E18Q	18	Missense	distal	-6	no	10.387	10.320	EPSD	COSMIC	7.604	Down-regulation
AGC_PKC_PKCd_PRKCD_ST	Q9UQL6	HDAC5	Q05655	PRKCD	S24	T31A	31	Missense	distal	7	no	10.387	10.369	EPSD	COSMIC;CCLE	7.604	Down-regulation
AGC_PKC_PKCd_PRKCD_ST	Q9UQL6	HDAC5	Q05655	PRKCD	S279	R284C	284	Missense	distal	5	no	12.144	11.579	EPSD	COSMIC	7.604	Down-regulation
AGC_PKC_PKCd_PRKCD_ST	Q9UQL6	HDAC5	Q05655	PRKCD	S279	S279N	279	Missense	central	0	yes	12.144	0.000	EPSD	COSMIC	7.604	Loss
AGC_PKC_PKCd_PRKCD_ST	Q9UQL6	HDAC5	Q05655	PRKCD	S279	R284S	284	Missense	distal	5	no	12.144	11.915	EPSD	COSMIC	7.604	Down-regulation
AGC_PKC_PKCd_PRKCD_ST	Q9UQL6	HDAC5	Q05655	PRKCD	S480	R476H	476	Missense	distal	-4	no	8.226	8.518	EPSD	COSMIC	7.604	Up-regulation
AGC_PKC_PKCd_PRKCD_ST	Q9UQL6	HDAC5	Q05655	PRKCD	S480	T473M	473	Missense	distal	-7	no	8.226	8.218	EPSD	COSMIC	7.604	Down-regulation
AGC_PKC_PKCd_PRKCD_ST	Q9UQL6	HDAC5	Q05655	PRKCD	S480	G474C	474	Missense	distal	-6	no	8.226	8.304	EPSD	COSMIC	7.604	Up-regulation
AGC_PKC_PKCd_PRKCD_ST	Q9UQL6	HDAC5	Q05655	PRKCD	S480	R476C	476	Missense	distal	-4	no	8.226	8.661	EPSD	COSMIC	7.604	Up-regulation
AGC_PKC_PKCd_PRKCD_ST	Q9UQL6	HDAC5	Q05655	PRKCD	S480	T483M	483	Missense	distal	3	no	8.226	8.095	EPSD	COSMIC	7.604	Down-regulation
AGC_PKC_PKCd_PRKCD_ST	Q9UQL6	HDAC5	Q05655	PRKCD	S480	A478V	478	Missense	proximal	-2	no	8.226	7.595	EPSD	COSMIC;CCLE	7.604	Loss
AGC_PKC_PKCd_PRKCD_ST	Q9UQL6	HDAC5	Q05655	PRKCD	S480	R482W	482	Missense	proximal	2	no	8.226	1.553	EPSD	COSMIC	7.604	Loss
AGC_PKC_PKCd_PRKCD_ST	Q9UQL6	HDAC5	Q05655	PRKCD	S661	R658L	658	Missense	distal	-3	no	7.626	2.440	EPSD	COSMIC	7.604	Loss
AGC_PKC_PKCd_PRKCD_ST	Q9UQL6	HDAC5	Q05655	PRKCD	S661	R658H	658	Missense	distal	-3	no	7.626	3.371	EPSD	COSMIC	7.604	Loss
AGC_PKC_PKCd_PRKCD_ST	Q9UQL6	HDAC5	Q05655	PRKCD	S661	T659S	659	Missense	proximal	-2	no	7.626	8.741	EPSD	COSMIC	7.604	Up-regulation
AGC_PKC_PKCd_PRKCD_ST	Q9UQL6	HDAC5	Q05655	PRKCD	S713	R717H	717	Missense	distal	4	no	7.680	7.137	EPSD	COSMIC	7.604	Loss
AGC_PKC_PKCd_PRKCD_ST	Q9UQL6	HDAC5	Q05655	PRKCD	S713	R710Q	710	Missense	distal	-3	no	7.680	2.522	EPSD	COSMIC	7.604	Loss
AGC_PKC_PKCd_PRKCD_ST	Q9UQL6	HDAC5	Q05655	PRKCD	S713	Q719H	719	Missense	distal	6	no	7.680	7.676	EPSD	COSMIC	7.604	Down-regulation
AGC_PKC_PKCd_PRKCD_ST	Q9UQL6	HDAC5	Q05655	PRKCD	S713	S713G	713	Missense	central	0	yes	7.680	0.000	EPSD	COSMIC	7.604	Loss
AGC_PKC_PKCd_PRKCD_ST	Q9UQL6	HDAC5	Q05655	PRKCD	S1108	E1106K	1106	Missense	proximal	-2	no	13.327	18.307	EPSD	COSMIC	7.604	Up-regulation
AGC_PKC_PKCd_PRKCD_ST	Q9UQL6	HDAC5	Q05655	PRKCD	S1108	A1104T	1104	Missense	distal	-4	no	13.327	13.297	EPSD	COSMIC;CCLE	7.604	Down-regulation
AGC_PKC_PKCd_PRKCD_ST	P18433	PTPRA	Q05655	PRKCD	S178	G175R	175	Missense	distal	-3	no	4.978	10.187	EPSD	COSMIC	7.604	Gain
AGC_PKC_PKCd_PRKCD_ST	P18433	PTPRA	Q05655	PRKCD	S193	E198K	198	Missense	distal	5	no	7.813	8.251	EPSD	COSMIC	7.604	Up-regulation
AGC_PKC_PKCd_PRKCD_ST	P18433	PTPRA	Q05655	PRKCD	S211	S213R	213	Missense	proximal	2	no	3.468	9.531	EPSD	COSMIC	7.604	Gain
AGC_PKC_PKCd_PRKCD_ST	P18433	PTPRA	Q05655	PRKCD	S213	S213R	213	Missense	central	0	yes	8.803	0.000	EPSD	COSMIC	7.604	Loss
AGC_PKC_PKCd_PRKCD_ST	P18433	PTPRA	Q05655	PRKCD	T214	S213R	213	Missense	proximal	-1	no	8.310	8.384	EPSD	COSMIC	7.604	Up-regulation
AGC_PKC_PKCd_PRKCD_ST	P18433	PTPRA	Q05655	PRKCD	S602	Q599K	599	Missense	distal	-3	no	5.081	9.204	EPSD	COSMIC	7.604	Gain
AGC_PKC_PKCd_PRKCD_ST	P18433	PTPRA	Q05655	PRKCD	T672	T672I	672	Missense	central	0	yes	8.225	0.000	EPSD	COSMIC	7.604	Loss
AGC_PKC_PKCd_PRKCD_ST	P18433	PTPRA	Q05655	PRKCD	S766	R771M	771	Missense	distal	5	no	8.609	8.122	EPSD	COSMIC;GDSC	7.604	Down-regulation
AGC_PKC_PKCd_PRKCD_ST	P18433	PTPRA	Q05655	PRKCD	S766	R768W	768	Missense	proximal	2	no	8.609	1.936	EPSD	COSMIC	7.604	Loss
AGC_PKC_PKCd_PRKCD_ST	P18433	PTPRA	Q05655	PRKCD	S766	T763A	763	Missense	distal	-3	no	8.609	9.363	EPSD	COSMIC	7.604	Up-regulation
AGC_PKC_PKCd_PRKCD_ST	P18433	PTPRA	Q05655	PRKCD	S766	R768Q	768	Missense	proximal	2	no	8.609	1.820	EPSD	COSMIC	7.604	Loss
AGC_PKC_PKCd_PRKCD_ST	P10415	BCL2	Q05655	PRKCD	S24	G27D	27	Missense	distal	3	no	12.548	12.581	EPSD	COSMIC	7.604	Up-regulation
AGC_PKC_PKCd_PRKCD_ST	P10415	BCL2	Q05655	PRKCD	S24	Y18F	18	Missense	distal	-6	no	12.548	12.485	EPSD	COSMIC	7.604	Down-regulation
AGC_PKC_PKCd_PRKCD_ST	P10415	BCL2	Q05655	PRKCD	S24	W30C	30	Missense	distal	6	no	12.548	12.564	EPSD	COSMIC	7.604	Up-regulation
AGC_PKC_PKCd_PRKCD_ST	P10415	BCL2	Q05655	PRKCD	S24	K17N	17	Missense	distal	-7	no	12.548	12.523	EPSD	COSMIC	7.604	Down-regulation
AGC_PKC_PKCd_PRKCD_ST	P10415	BCL2	Q05655	PRKCD	S24	Y28F	28	Missense	distal	4	no	12.548	12.730	EPSD	COSMIC	7.604	Up-regulation
AGC_PKC_PKCd_PRKCD_ST	P10415	BCL2	Q05655	PRKCD	S24	Y21H	21	Missense	distal	-3	no	12.548	14.171	EPSD	COSMIC	7.604	Up-regulation
AGC_PKC_PKCd_PRKCD_ST	P10415	BCL2	Q05655	PRKCD	S24	D31A	31	Missense	distal	7	no	12.548	12.564	EPSD	COSMIC	7.604	Up-regulation
AGC_PKC_PKCd_PRKCD_ST	P10415	BCL2	Q05655	PRKCD	S24	K17E	17	Missense	distal	-7	no	12.548	12.525	EPSD	COSMIC	7.604	Down-regulation
AGC_PKC_PKCd_PRKCD_ST	P10415	BCL2	Q05655	PRKCD	S24	E29Q	29	Missense	distal	5	no	12.548	12.590	EPSD	COSMIC	7.604	Up-regulation
AGC_PKC_PKCd_PRKCD_ST	P10415	BCL2	Q05655	PRKCD	S24	Y21C	21	Missense	distal	-3	no	12.548	13.107	EPSD	COSMIC	7.604	Up-regulation
AGC_PKC_PKCd_PRKCD_ST	P10415	BCL2	Q05655	PRKCD	S24	R26K	26	Missense	proximal	2	no	12.548	11.371	EPSD	COSMIC	7.604	Down-regulation
AGC_PKC_PKCd_PRKCD_ST	P10415	BCL2	Q05655	PRKCD	T56	H58R	58	Missense	proximal	2	no	3.439	9.000	EPSD	COSMIC	7.604	Gain
AGC_PKC_PKCd_PRKCD_ST	P10415	BCL2	Q05655	PRKCD	S70	T74N	74	Missense	distal	4	no	8.616	8.468	PhosphoSitePlus	COSMIC	7.604	Down-regulation
AGC_PKC_PKCd_PRKCD_ST	P10415	BCL2	Q05655	PRKCD	S70	T69A	69	Missense	proximal	-1	no	8.616	8.600	PhosphoSitePlus	COSMIC	7.604	Down-regulation
AGC_PKC_PKCd_PRKCD_ST	P10415	BCL2	Q05655	PRKCD	S70	A67V	67	Missense	distal	-3	no	8.616	8.154	PhosphoSitePlus	COSMIC	7.604	Down-regulation
AGC_PKC_PKCd_PRKCD_ST	P10415	BCL2	Q05655	PRKCD	S70	P65S	65	Missense	distal	-5	no	8.616	8.624	PhosphoSitePlus	COSMIC	7.604	Up-regulation
AGC_PKC_PKCd_PRKCD_ST	P10415	BCL2	Q05655	PRKCD	S70	A76T	76	Missense	distal	6	no	8.616	8.627	PhosphoSitePlus	COSMIC	7.604	Up-regulation
AGC_PKC_PKCd_PRKCD_ST	P10415	BCL2	Q05655	PRKCD	S70	A77V	77	Missense	distal	7	no	8.616	8.577	PhosphoSitePlus	COSMIC	7.604	Down-regulation
AGC_PKC_PKCd_PRKCD_ST	P10415	BCL2	Q05655	PRKCD	S70	P71S	71	Missense	proximal	1	no	8.616	8.596	PhosphoSitePlus	COSMIC	7.604	Down-regulation
AGC_PKC_PKCd_PRKCD_ST	P10415	BCL2	Q05655	PRKCD	S70	D64G	64	Missense	distal	-6	no	8.616	8.654	PhosphoSitePlus	COSMIC	7.604	Up-regulation
AGC_PKC_PKCd_PRKCD_ST	P10415	BCL2	Q05655	PRKCD	S70	A76S	76	Missense	distal	6	no	8.616	8.633	PhosphoSitePlus	COSMIC	7.604	Up-regulation
AGC_PKC_PKCd_PRKCD_ST	P10415	BCL2	Q05655	PRKCD	S70	T74A	74	Missense	distal	4	no	8.616	8.584	PhosphoSitePlus	COSMIC	7.604	Down-regulation
AGC_PKC_PKCd_PRKCD_ST	P10415	BCL2	Q05655	PRKCD	S70	T74I	74	Missense	distal	4	no	8.616	8.363	PhosphoSitePlus	COSMIC	7.604	Down-regulation
AGC_PKC_PKCd_PRKCD_ST	P10415	BCL2	Q05655	PRKCD	S70	T69P	69	Missense	proximal	-1	no	8.616	8.637	PhosphoSitePlus	COSMIC;CCLE	7.604	Up-regulation
AGC_PKC_PKCd_PRKCD_ST	P10415	BCL2	Q05655	PRKCD	S70	V66I	66	Missense	distal	-4	no	8.616	8.658	PhosphoSitePlus	COSMIC	7.604	Up-regulation
AGC_PKC_PKCd_PRKCD_ST	P10415	BCL2	Q05655	PRKCD	S70	P65Q	65	Missense	distal	-5	no	8.616	8.548	PhosphoSitePlus	COSMIC	7.604	Down-regulation
AGC_PKC_PKCd_PRKCD_ST	P10415	BCL2	Q05655	PRKCD	S216	S213A	213	Missense	distal	-3	no	9.483	9.719	EPSD	COSMIC	7.604	Up-regulation
AGC_PKC_PKCd_PRKCD_ST	P10415	BCL2	Q05655	PRKCD	S216	S213F	213	Missense	distal	-3	no	9.483	9.535	EPSD	COSMIC	7.604	Up-regulation
AGC_PKC_PKCd_PRKCD_ST	P10415	BCL2	Q05655	PRKCD	S216	F210C	210	Missense	distal	-6	no	9.483	9.548	EPSD	COSMIC	7.604	Up-regulation
AGC_PKC_PKCd_PRKCD_ST	P61978	HNRNPK	Q05655	PRKCD	S276	M283T	283	Missense	distal	7	no	9.475	9.525	EPSD	COSMIC	7.604	Up-regulation
AGC_PKC_PKCd_PRKCD_ST	P61978	HNRNPK	Q05655	PRKCD	S284	M283T	283	Missense	proximal	-1	no	9.561	9.620	EPSD	COSMIC	7.604	Up-regulation
AGC_PKC_PKCd_PRKCD_ST	P61978	HNRNPK	Q05655	PRKCD	S302	G297C	297	Missense	distal	-5	no	7.752	7.689	PhosphoSitePlus	COSMIC;CCLE	7.604	Down-regulation
AGC_PKC_PKCd_PRKCD_ST	P61978	HNRNPK	Q05655	PRKCD	S302	R299W	299	Missense	distal	-3	no	7.752	2.456	PhosphoSitePlus	COSMIC	7.604	Loss
AGC_PKC_PKCd_PRKCD_ST	P61978	HNRNPK	Q05655	PRKCD	S302	G298V	298	Missense	distal	-4	no	7.752	7.768	PhosphoSitePlus	COSMIC	7.604	Up-regulation
AGC_PKC_PKCd_PRKCD_ST	P61978	HNRNPK	Q05655	PRKCD	S302	G295R	295	Missense	distal	-7	no	7.752	7.774	PhosphoSitePlus	COSMIC	7.604	Up-regulation
AGC_PKC_PKCd_PRKCD_ST	Q9UQ13	SHOC2	Q05655	PRKCD	S85	K83Q	83	Missense	proximal	-2	no	11.553	7.364	EPSD	COSMIC	7.604	Loss
AGC_PKC_PKCd_PRKCD_ST	Q9UQ13	SHOC2	Q05655	PRKCD	S86	K83Q	83	Missense	distal	-3	no	11.454	7.332	EPSD	COSMIC	7.604	Loss
AGC_PKC_PKCd_PRKCD_ST	Q9UQ13	SHOC2	Q05655	PRKCD	S118	P116L	116	Missense	proximal	-2	no	9.632	7.963	EPSD	COSMIC	7.604	Down-regulation
AGC_PKC_PKCd_PRKCD_ST	Q9UQ13	SHOC2	Q05655	PRKCD	S221	R223Q	223	Missense	proximal	2	no	10.060	3.270	EPSD	COSMIC	7.604	Loss
AGC_PKC_PKCd_PRKCD_ST	Q9UQ13	SHOC2	Q05655	PRKCD	S297	P300H	300	Missense	distal	3	no	10.402	10.377	EPSD;PhosphoSitePlus	COSMIC	7.604	Down-regulation
AGC_PKC_PKCd_PRKCD_ST	Q9UQ13	SHOC2	Q05655	PRKCD	S297	P300S	300	Missense	distal	3	no	10.402	10.408	EPSD;PhosphoSitePlus	COSMIC	7.604	Up-regulation
AGC_PKC_PKCd_PRKCD_ST	Q9UQ13	SHOC2	Q05655	PRKCD	S297	A298T	298	Missense	proximal	1	no	10.402	10.465	EPSD;PhosphoSitePlus	COSMIC	7.604	Up-regulation
AGC_PKC_PKCd_PRKCD_ST	P53004	BLVRA	Q05655	PRKCD	S21	S21F	21	Missense	central	0	yes	15.400	0.000	EPSD;PhosphoSitePlus	COSMIC	7.604	Loss
AGC_PKC_PKCd_PRKCD_ST	P53004	BLVRA	Q05655	PRKCD	S230	R225Q	225	Missense	distal	-5	no	8.620	8.270	EPSD;PhosphoSitePlus	COSMIC	7.604	Down-regulation
AGC_PKC_PKCd_PRKCD_ST	P53004	BLVRA	Q05655	PRKCD	S230	S235Y	235	Missense	distal	5	no	8.620	8.282	EPSD;PhosphoSitePlus	COSMIC	7.604	Down-regulation
AGC_PKC_PKCd_PRKCD_ST	P53004	BLVRA	Q05655	PRKCD	S230	R227K	227	Missense	distal	-3	no	8.620	7.585	EPSD;PhosphoSitePlus	COSMIC	7.604	Loss
AGC_PKC_PKCd_PRKCD_ST	P15941	MUC1	Q05655	PRKCD	T1202	P1205L	1205	Missense	distal	3	no	7.788	7.507	EPSD	COSMIC	7.604	Loss
AGC_PKC_PKCd_PRKCD_ST	P15941	MUC1	Q05655	PRKCD	T1202	P1205S	1205	Missense	distal	3	no	7.788	7.794	EPSD	COSMIC	7.604	Up-regulation
AGC_PKC_PKCd_PRKCD_ST	P15941	MUC1	Q05655	PRKCD	T1224	P1228R	1228	Missense	distal	4	no	8.317	8.748	PhosphoSitePlus	COSMIC	7.604	Up-regulation
AGC_PKC_PKCd_PRKCD_ST	P35611	ADD1	Q05655	PRKCD	S133	P126A	126	Missense	distal	-7	no	7.860	7.854	EPSD	COSMIC	7.604	Down-regulation
AGC_PKC_PKCd_PRKCD_ST	P35611	ADD1	Q05655	PRKCD	S355	G361V	361	Missense	distal	6	no	7.607	7.598	EPSD	COSMIC	7.604	Loss
AGC_PKC_PKCd_PRKCD_ST	P35611	ADD1	Q05655	PRKCD	S404	D409N	409	Missense	distal	5	no	12.122	12.068	EPSD	COSMIC;GDSC;CCLE	7.604	Down-regulation
AGC_PKC_PKCd_PRKCD_ST	P35611	ADD1	Q05655	PRKCD	S408	D409N	409	Missense	proximal	1	no	11.745	11.738	EPSD	COSMIC;GDSC;CCLE	7.604	Down-regulation
AGC_PKC_PKCd_PRKCD_ST	P35611	ADD1	Q05655	PRKCD	S436	T429A	429	Missense	distal	-7	no	7.747	7.745	EPSD	COSMIC	7.604	Down-regulation
AGC_PKC_PKCd_PRKCD_ST	P35611	ADD1	Q05655	PRKCD	S481	G477E	477	Missense	distal	-4	no	8.617	8.598	EPSD	COSMIC	7.604	Down-regulation
AGC_PKC_PKCd_PRKCD_ST	P35611	ADD1	Q05655	PRKCD	S481	K474T	474	Missense	distal	-7	no	8.617	8.598	EPSD	COSMIC	7.604	Down-regulation
AGC_PKC_PKCd_PRKCD_ST	P35611	ADD1	Q05655	PRKCD	S669	P670F	670	Missense	proximal	1	no	8.801	8.732	EPSD	COSMIC	7.604	Down-regulation
AGC_PKC_PKCd_PRKCD_ST	P35611	ADD1	Q05655	PRKCD	S716	G709V	709	Missense	distal	-7	no	14.867	14.865	EPSD	COSMIC	7.604	Down-regulation
AGC_PKC_PKCd_PRKCD_ST	P35611	ADD1	Q05655	PRKCD	S716	S710F	710	Missense	distal	-6	no	14.867	15.072	EPSD	COSMIC	7.604	Up-regulation
AGC_PKC_PKCd_PRKCD_ST	P35611	ADD1	Q05655	PRKCD	S716	G712D	712	Missense	distal	-4	no	14.867	14.843	EPSD	COSMIC	7.604	Down-regulation
AGC_PKC_PKCd_PRKCD_ST	P35611	ADD1	Q05655	PRKCD	S726	S726L	726	Missense	central	0	yes	10.284	0.000	PhosphoSitePlus	COSMIC	7.604	Loss
AGC_PKC_PKCd_PRKCD_ST	P35611	ADD1	Q05655	PRKCD	S731	S726L	726	Missense	distal	-5	no	13.559	13.404	EPSD	COSMIC	7.604	Down-regulation
AGC_PKC_PKCd_PRKCD_ST	P14598	NCF1	Q05655	PRKCD	T45	R42W	42	Missense	distal	-3	no	9.067	3.771	EPSD	COSMIC	7.604	Loss
AGC_PKC_PKCd_PRKCD_ST	P14598	NCF1	Q05655	PRKCD	T356	P349R	349	Missense	distal	-7	no	12.051	12.063	EPSD	COSMIC	7.604	Up-regulation
AGC_PKC_PKCd_PRKCD_ST	Q8TCJ0	FBXO25	Q05655	PRKCD	S139	Q136R	136	Missense	distal	-3	no	2.789	7.947	EPSD	COSMIC	7.604	Gain
AGC_PKC_PKCd_PRKCD_ST	Q8TCJ0	FBXO25	Q05655	PRKCD	S289	L286F	286	Missense	distal	-3	no	6.993	7.656	EPSD	COSMIC;GDSC;CCLE	7.604	Gain
AGC_PKC_PKCd_PRKCD_ST	Q16206	ENOX2	Q05655	PRKCD	S240	P242S	242	Missense	proximal	2	no	9.670	9.425	EPSD	COSMIC	7.604	Down-regulation
AGC_PKC_PKCd_PRKCD_ST	Q16206	ENOX2	Q05655	PRKCD	S240	P243S	243	Missense	distal	3	no	9.670	9.676	EPSD	COSMIC	7.604	Up-regulation
AGC_PKC_PKCd_PRKCD_ST	Q16206	ENOX2	Q05655	PRKCD	S504	E501K	501	Missense	distal	-3	no	6.956	11.342	PhosphoSitePlus	COSMIC	7.604	Gain
AGC_PKC_PKCd_PRKCD_ST	Q16206	ENOX2	Q05655	PRKCD	S531	S531F	531	Missense	central	0	yes	8.851	0.000	EPSD	COSMIC	7.604	Loss
AGC_PKC_PKCd_PRKCD_ST	P19429	TNNI3	Q05655	PRKCD	S23	R27H	27	Missense	distal	4	no	15.118	14.575	EPSD;PhosphoSitePlus	COSMIC	7.604	Down-regulation
AGC_PKC_PKCd_PRKCD_ST	P19429	TNNI3	Q05655	PRKCD	S23	S23P	23	Missense	central	0	yes	15.118	0.000	EPSD;PhosphoSitePlus	COSMIC	7.604	Loss
AGC_PKC_PKCd_PRKCD_ST	P19429	TNNI3	Q05655	PRKCD	S24	R27H	27	Missense	distal	3	no	14.127	13.239	EPSD;PhosphoSitePlus	COSMIC	7.604	Down-regulation
AGC_PKC_PKCd_PRKCD_ST	P19429	TNNI3	Q05655	PRKCD	S24	S23P	23	Missense	proximal	-1	no	14.127	14.086	EPSD;PhosphoSitePlus	COSMIC	7.604	Down-regulation
AGC_PKC_PKCd_PRKCD_ST	P19429	TNNI3	Q05655	PRKCD	S39	H34Q	34	Missense	distal	-5	no	10.376	10.362	EPSD	COSMIC	7.604	Down-regulation
AGC_PKC_PKCd_PRKCD_ST	P19429	TNNI3	Q05655	PRKCD	S39	E32A	32	Missense	distal	-7	no	10.376	10.378	EPSD	COSMIC	7.604	Up-regulation
AGC_PKC_PKCd_PRKCD_ST	P19429	TNNI3	Q05655	PRKCD	S39	K37T	37	Missense	proximal	-2	no	10.376	5.659	EPSD	COSMIC	7.604	Loss
AGC_PKC_PKCd_PRKCD_ST	P19429	TNNI3	Q05655	PRKCD	S77	Q81H	81	Missense	distal	4	no	15.339	15.384	EPSD	COSMIC	7.604	Up-regulation
AGC_PKC_PKCd_PRKCD_ST	P19429	TNNI3	Q05655	PRKCD	S77	A75S	75	Missense	proximal	-2	no	15.339	15.301	EPSD	COSMIC	7.604	Down-regulation
AGC_PKC_PKCd_PRKCD_ST	P19429	TNNI3	Q05655	PRKCD	S77	G73W	73	Missense	distal	-4	no	15.339	15.486	EPSD	COSMIC	7.604	Up-regulation
AGC_PKC_PKCd_PRKCD_ST	P19429	TNNI3	Q05655	PRKCD	S77	P82S	82	Missense	distal	5	no	15.339	15.307	EPSD	COSMIC	7.604	Down-regulation
AGC_PKC_PKCd_PRKCD_ST	P19429	TNNI3	Q05655	PRKCD	T143	R141Q	141	Missense	proximal	-2	no	18.627	13.192	PhosphoSitePlus;EPSD	COSMIC	7.604	Down-regulation
AGC_PKC_PKCd_PRKCD_ST	P19429	TNNI3	Q05655	PRKCD	T143	R146I	146	Missense	distal	3	no	18.627	17.315	PhosphoSitePlus;EPSD	COSMIC	7.604	Down-regulation
AGC_PKC_PKCd_PRKCD_ST	P19429	TNNI3	Q05655	PRKCD	S150	Q156H	156	Missense	distal	6	no	8.191	8.188	EPSD	COSMIC	7.604	Down-regulation
AGC_PKC_PKCd_PRKCD_ST	P19429	TNNI3	Q05655	PRKCD	S150	A157V	157	Missense	distal	7	no	8.191	8.153	EPSD	COSMIC	7.604	Down-regulation
AGC_PKC_PKCd_PRKCD_ST	P19429	TNNI3	Q05655	PRKCD	S150	R146I	146	Missense	distal	-4	no	8.191	8.634	EPSD	COSMIC	7.604	Up-regulation
AGC_PKC_PKCd_PRKCD_ST	P19429	TNNI3	Q05655	PRKCD	T181	E187G	187	Missense	distal	6	no	9.017	9.011	EPSD	COSMIC	7.604	Down-regulation
AGC_PKC_PKCd_PRKCD_ST	P19429	TNNI3	Q05655	PRKCD	T181	V176G	176	Missense	distal	-5	no	9.017	9.033	EPSD	COSMIC	7.604	Up-regulation
AGC_PKC_PKCd_PRKCD_ST	P15407	FOSL1	Q05655	PRKCD	S251	D257H	257	Missense	distal	6	no	9.698	9.701	EPSD	COSMIC	7.604	Up-regulation
AGC_PKC_PKCd_PRKCD_ST	P15407	FOSL1	Q05655	PRKCD	S251	G256E	256	Missense	distal	5	no	9.698	9.765	EPSD	COSMIC	7.604	Up-regulation
AGC_PKC_PKCd_PRKCD_ST	P15407	FOSL1	Q05655	PRKCD	S251	C244F	244	Missense	distal	-7	no	9.698	9.702	EPSD	COSMIC	7.604	Up-regulation
AGC_PKC_PKCd_PRKCD_ST	P15407	FOSL1	Q05655	PRKCD	S252	D257H	257	Missense	distal	5	no	11.747	11.788	EPSD	COSMIC	7.604	Up-regulation
AGC_PKC_PKCd_PRKCD_ST	P15407	FOSL1	Q05655	PRKCD	S252	G256E	256	Missense	distal	4	no	11.747	11.813	EPSD	COSMIC	7.604	Up-regulation
AGC_PKC_PKCd_PRKCD_ST	O76090	BEST1	Q05655	PRKCD	S16	N11D	11	Missense	distal	-5	no	9.342	9.365	EPSD	COSMIC	7.604	Up-regulation
AGC_PKC_PKCd_PRKCD_ST	O76090	BEST1	Q05655	PRKCD	S358	Q353K	353	Missense	distal	-5	no	13.384	13.709	PhosphoSitePlus	COSMIC	7.604	Up-regulation
AGC_PKC_PKCd_PRKCD_ST	O76090	BEST1	Q05655	PRKCD	S358	R356Q	356	Missense	proximal	-2	no	13.384	7.950	PhosphoSitePlus	COSMIC;CCLE	7.604	Down-regulation
AGC_PKC_PKCd_PRKCD_ST	O76090	BEST1	Q05655	PRKCD	S358	M360T	360	Missense	proximal	2	no	13.384	13.320	PhosphoSitePlus	COSMIC;CCLE	7.604	Down-regulation
AGC_PKC_PKCd_PRKCD_ST	Q9UBS0	RPS6KB2	Q05655	PRKCD	S410	R413C	413	Missense	distal	3	no	13.029	11.755	EPSD	COSMIC	7.604	Down-regulation
AGC_PKC_PKCd_PRKCD_ST	Q9UBS0	RPS6KB2	Q05655	PRKCD	S410	R413H	413	Missense	distal	3	no	13.029	12.141	EPSD	COSMIC	7.604	Down-regulation
AGC_PKC_PKCd_PRKCD_ST	Q9UBS0	RPS6KB2	Q05655	PRKCD	S416	P421S	421	Missense	distal	5	no	9.315	9.283	EPSD	COSMIC	7.604	Down-regulation
AGC_PKC_PKCd_PRKCD_ST	Q9UBS0	RPS6KB2	Q05655	PRKCD	S416	R413C	413	Missense	distal	-3	no	9.315	3.995	EPSD	COSMIC	7.604	Loss
AGC_PKC_PKCd_PRKCD_ST	Q9UBS0	RPS6KB2	Q05655	PRKCD	S416	R413H	413	Missense	distal	-3	no	9.315	5.060	EPSD	COSMIC	7.604	Loss
AGC_PKC_PKCd_PRKCD_ST	Q9UBS0	RPS6KB2	Q05655	PRKCD	S416	P421L	421	Missense	distal	5	no	9.315	9.093	EPSD	COSMIC	7.604	Down-regulation
AGC_PKC_PKCd_PRKCD_ST	Q9UBS0	RPS6KB2	Q05655	PRKCD	S417	R413C	413	Missense	distal	-4	no	7.303	7.738	EPSD	COSMIC	7.604	Gain
AGC_PKC_PKCd_PRKCD_ST	Q9UBS0	RPS6KB2	Q05655	PRKCD	S436	G432R	432	Missense	distal	-4	no	7.834	7.449	EPSD	COSMIC	7.604	Loss
AGC_PKC_PKCd_PRKCD_ST	Q9UBS0	RPS6KB2	Q05655	PRKCD	S436	T443M	443	Missense	distal	7	no	7.834	7.783	EPSD	COSMIC	7.604	Down-regulation
AGC_PKC_PKCd_PRKCD_ST	Q9UBS0	RPS6KB2	Q05655	PRKCD	S468	S468P	468	Missense	central	0	yes	11.931	0.000	EPSD	COSMIC	7.604	Loss
AGC_PKC_PKCd_PRKCD_ST	Q9UBS0	RPS6KB2	Q05655	PRKCD	S468	P463S	463	Missense	distal	-5	no	11.931	11.940	EPSD	COSMIC	7.604	Up-regulation
AGC_PKC_PKCd_PRKCD_ST	Q9UBS0	RPS6KB2	Q05655	PRKCD	S468	R475G	475	Missense	distal	7	no	11.931	11.823	EPSD	COSMIC	7.604	Down-regulation
AGC_PKC_PKCd_PRKCD_ST	Q9UBS0	RPS6KB2	Q05655	PRKCD	S468	P467H	467	Missense	proximal	-1	no	11.931	11.901	EPSD	COSMIC	7.604	Down-regulation
AGC_PKC_PKCd_PRKCD_ST	Q9UBS0	RPS6KB2	Q05655	PRKCD	S468	R465H	465	Missense	distal	-3	no	11.931	7.676	EPSD	COSMIC	7.604	Down-regulation
AGC_PKC_PKCd_PRKCD_ST	Q9UBS0	RPS6KB2	Q05655	PRKCD	T470	S468P	468	Missense	proximal	-2	no	9.021	9.406	EPSD	COSMIC	7.604	Up-regulation
AGC_PKC_PKCd_PRKCD_ST	Q9UBS0	RPS6KB2	Q05655	PRKCD	T470	R477H	477	Missense	distal	7	no	9.021	8.934	EPSD	COSMIC	7.604	Down-regulation
AGC_PKC_PKCd_PRKCD_ST	Q9UBS0	RPS6KB2	Q05655	PRKCD	T470	R475G	475	Missense	distal	5	no	9.021	8.577	EPSD	COSMIC	7.604	Down-regulation
AGC_PKC_PKCd_PRKCD_ST	Q9UBS0	RPS6KB2	Q05655	PRKCD	T470	P467H	467	Missense	distal	-3	no	9.021	9.009	EPSD	COSMIC	7.604	Down-regulation
AGC_PKC_PKCd_PRKCD_ST	Q9UBS0	RPS6KB2	Q05655	PRKCD	T470	R465H	465	Missense	distal	-5	no	9.021	8.685	EPSD	COSMIC	7.604	Down-regulation
AGC_PKC_PKCd_PRKCD_ST	Q9UBS0	RPS6KB2	Q05655	PRKCD	S473	R479H	479	Missense	distal	6	no	13.943	13.893	PhosphoSitePlus	COSMIC;CCLE	7.604	Down-regulation
AGC_PKC_PKCd_PRKCD_ST	Q9UBS0	RPS6KB2	Q05655	PRKCD	S473	S468P	468	Missense	distal	-5	no	13.943	13.934	PhosphoSitePlus	COSMIC	7.604	Down-regulation
AGC_PKC_PKCd_PRKCD_ST	Q9UBS0	RPS6KB2	Q05655	PRKCD	S473	P480Q	480	Missense	distal	7	no	13.943	13.944	PhosphoSitePlus	COSMIC	7.604	Up-regulation
AGC_PKC_PKCd_PRKCD_ST	Q9UBS0	RPS6KB2	Q05655	PRKCD	S473	R477H	477	Missense	distal	4	no	13.943	13.399	PhosphoSitePlus	COSMIC	7.604	Down-regulation
AGC_PKC_PKCd_PRKCD_ST	Q9UBS0	RPS6KB2	Q05655	PRKCD	S473	R475G	475	Missense	proximal	2	no	13.943	7.611	PhosphoSitePlus	COSMIC	7.604	Down-regulation
AGC_PKC_PKCd_PRKCD_ST	Q9UBS0	RPS6KB2	Q05655	PRKCD	S473	P467H	467	Missense	distal	-6	no	13.943	13.967	PhosphoSitePlus	COSMIC	7.604	Up-regulation
AGC_PKC_PKCd_PRKCD_ST	Q9H257	CARD9	Q05655	PRKCD	T95	K97R	97	Missense	proximal	2	no	12.906	14.083	EPSD	COSMIC	7.604	Up-regulation
AGC_PKC_PKCd_PRKCD_ST	Q9H257	CARD9	Q05655	PRKCD	T231	H230Y	230	Missense	proximal	-1	no	16.196	16.121	PhosphoSitePlus	COSMIC	7.604	Down-regulation
AGC_PKC_PKCd_PRKCD_ST	Q9H257	CARD9	Q05655	PRKCD	S303	Q310R	310	Missense	distal	7	no	9.149	9.240	EPSD	COSMIC;GDSC;CCLE	7.604	Up-regulation
AGC_PKC_PKCd_PRKCD_ST	Q9H257	CARD9	Q05655	PRKCD	S303	R309C	309	Missense	distal	6	no	9.149	9.073	EPSD	COSMIC	7.604	Down-regulation
AGC_PKC_PKCd_PRKCD_ST	Q9H257	CARD9	Q05655	PRKCD	S303	R305H	305	Missense	proximal	2	no	9.149	3.588	EPSD	COSMIC	7.604	Loss
AGC_PKC_PKCd_PRKCD_ST	Q9H257	CARD9	Q05655	PRKCD	S431	S435P	435	Missense	distal	4	no	10.159	10.198	EPSD	COSMIC	7.604	Up-regulation
AGC_PKC_PKCd_PRKCD_ST	P05107	ITGB2	Q05655	PRKCD	S490	R488W	488	Missense	proximal	-2	no	7.721	1.467	EPSD	COSMIC	7.604	Loss
AGC_PKC_PKCd_PRKCD_ST	P05107	ITGB2	Q05655	PRKCD	S496	S503F	503	Missense	distal	7	no	8.090	8.042	EPSD	COSMIC	7.604	Down-regulation
AGC_PKC_PKCd_PRKCD_ST	P05107	ITGB2	Q05655	PRKCD	S591	R586W	586	Missense	distal	-5	no	8.634	8.089	EPSD	COSMIC	7.604	Down-regulation
AGC_PKC_PKCd_PRKCD_ST	P05107	ITGB2	Q05655	PRKCD	S591	R595Q	595	Missense	distal	4	no	8.634	8.046	EPSD	COSMIC;GDSC	7.604	Down-regulation
AGC_PKC_PKCd_PRKCD_ST	P05107	ITGB2	Q05655	PRKCD	S591	R593H	593	Missense	proximal	2	no	8.634	3.073	EPSD	COSMIC	7.604	Loss
AGC_PKC_PKCd_PRKCD_ST	Q05655	PRKCD	Q05655	PRKCD	T38	S37N	37	Missense	proximal	-1	no	8.523	8.410	EPSD	COSMIC;GDSC;CCLE	7.604	Down-regulation
AGC_PKC_PKCd_PRKCD_ST	Q05655	PRKCD	Q05655	PRKCD	S130	V125M	125	Missense	distal	-5	no	13.856	13.855	EPSD	COSMIC	7.604	Down-regulation
AGC_PKC_PKCd_PRKCD_ST	Q05655	PRKCD	Q05655	PRKCD	T295	N292S	292	Missense	distal	-3	no	7.050	7.615	EPSD;PhosphoSitePlus	COSMIC	7.604	Gain
AGC_PKC_PKCd_PRKCD_ST	Q05655	PRKCD	Q05655	PRKCD	S299	A298T	298	Missense	proximal	-1	no	13.252	13.268	EPSD;PhosphoSitePlus	COSMIC	7.604	Up-regulation
AGC_PKC_PKCd_PRKCD_ST	Q05655	PRKCD	Q05655	PRKCD	S299	S306Y	306	Missense	distal	7	no	13.252	13.179	EPSD;PhosphoSitePlus	COSMIC;GDSC;CCLE	7.604	Down-regulation
AGC_PKC_PKCd_PRKCD_ST	Q05655	PRKCD	Q05655	PRKCD	S299	N292S	292	Missense	distal	-7	no	13.252	13.263	EPSD;PhosphoSitePlus	COSMIC	7.604	Up-regulation
AGC_PKC_PKCd_PRKCD_ST	Q05655	PRKCD	Q05655	PRKCD	S299	S299F	299	Missense	central	0	yes	13.252	0.000	EPSD;PhosphoSitePlus	COSMIC	7.604	Loss
AGC_PKC_PKCd_PRKCD_ST	Q05655	PRKCD	Q05655	PRKCD	S302	A298T	298	Missense	distal	-4	no	9.128	9.097	EPSD;PhosphoSitePlus	COSMIC	7.604	Down-regulation
AGC_PKC_PKCd_PRKCD_ST	Q05655	PRKCD	Q05655	PRKCD	S302	S307L	307	Missense	distal	5	no	9.128	8.938	EPSD;PhosphoSitePlus	COSMIC;GDSC;CCLE	7.604	Down-regulation
AGC_PKC_PKCd_PRKCD_ST	Q05655	PRKCD	Q05655	PRKCD	S302	S306Y	306	Missense	distal	4	no	9.128	8.801	EPSD;PhosphoSitePlus	COSMIC;GDSC;CCLE	7.604	Down-regulation
AGC_PKC_PKCd_PRKCD_ST	Q05655	PRKCD	Q05655	PRKCD	S302	S299F	299	Missense	distal	-3	no	9.128	9.179	EPSD;PhosphoSitePlus	COSMIC	7.604	Up-regulation
AGC_PKC_PKCd_PRKCD_ST	Q05655	PRKCD	Q05655	PRKCD	S304	A298T	298	Missense	distal	-6	no	8.265	8.188	EPSD;PhosphoSitePlus	COSMIC	7.604	Down-regulation
AGC_PKC_PKCd_PRKCD_ST	Q05655	PRKCD	Q05655	PRKCD	S304	S307L	307	Missense	distal	3	no	8.265	7.978	EPSD;PhosphoSitePlus	COSMIC;GDSC;CCLE	7.604	Down-regulation
AGC_PKC_PKCd_PRKCD_ST	Q05655	PRKCD	Q05655	PRKCD	S304	S306Y	306	Missense	proximal	2	no	8.265	6.786	EPSD;PhosphoSitePlus	COSMIC;GDSC;CCLE	7.604	Loss
AGC_PKC_PKCd_PRKCD_ST	Q05655	PRKCD	Q05655	PRKCD	S304	S299F	299	Missense	distal	-5	no	8.265	8.155	EPSD;PhosphoSitePlus	COSMIC	7.604	Down-regulation
AGC_PKC_PKCd_PRKCD_ST	Q05655	PRKCD	Q05655	PRKCD	S559	R561P	561	Missense	proximal	2	no	8.200	2.381	EPSD	COSMIC	7.604	Loss
AGC_PKC_PKCd_PRKCD_ST	Q05655	PRKCD	Q05655	PRKCD	S631	E636Q	636	Missense	distal	5	no	7.637	7.680	EPSD	COSMIC	7.604	Up-regulation
AGC_PKC_PKCd_PRKCD_ST	Q05655	PRKCD	Q05655	PRKCD	S645	K641E	641	Missense	distal	-4	no	8.728	9.119	EPSD;PhosphoSitePlus	COSMIC	7.604	Up-regulation
AGC_PKC_PKCd_PRKCD_ST	Q05655	PRKCD	Q05655	PRKCD	S645	S645F	645	Missense	central	0	yes	8.728	0.000	EPSD;PhosphoSitePlus	COSMIC	7.604	Loss
AGC_PKC_PKCd_PRKCD_ST	Q05655	PRKCD	Q05655	PRKCD	S645	E640G	640	Missense	distal	-5	no	8.728	8.698	EPSD;PhosphoSitePlus	COSMIC	7.604	Down-regulation
AGC_PKC_PKCd_PRKCD_ST	P13796	LCP1	Q05655	PRKCD	S5	D8N	8	Missense	distal	3	no	9.438	9.413	PhosphoSitePlus	COSMIC	7.604	Down-regulation
AGC_PKC_PKCd_PRKCD_ST	P13796	LCP1	Q05655	PRKCD	S5	E9D	9	Missense	distal	4	no	9.438	9.412	PhosphoSitePlus	COSMIC	7.604	Down-regulation
AGC_PKC_PKCd_PRKCD_ST	P13796	LCP1	Q05655	PRKCD	T89	V86F	86	Missense	distal	-3	no	7.876	8.153	EPSD	COSMIC	7.604	Up-regulation
AGC_PKC_PKCd_PRKCD_ST	P13796	LCP1	Q05655	PRKCD	T89	S83T	83	Missense	distal	-6	no	7.876	7.916	EPSD	COSMIC	7.604	Up-regulation
AGC_PKC_PKCd_PRKCD_ST	P13796	LCP1	Q05655	PRKCD	T89	V86I	86	Missense	distal	-3	no	7.876	7.035	EPSD	COSMIC	7.604	Loss
AGC_PKC_PKCd_PRKCD_ST	P13796	LCP1	Q05655	PRKCD	T503	L507I	507	Missense	distal	4	no	9.340	9.219	EPSD	COSMIC	7.604	Down-regulation
AGC_PKC_PKCd_PRKCD_ST	P13796	LCP1	Q05655	PRKCD	S535	K533E	533	Missense	proximal	-2	no	8.583	3.603	EPSD	COSMIC	7.604	Loss
AGC_PKC_PKCd_PRKCD_ST	P13796	LCP1	Q05655	PRKCD	S535	K542N	542	Missense	distal	7	no	8.583	8.442	EPSD	COSMIC	7.604	Down-regulation
AGC_PKC_PKCd_PRKCD_ST	P13796	LCP1	Q05655	PRKCD	S536	K533E	533	Missense	distal	-3	no	10.011	5.626	EPSD	COSMIC	7.604	Loss
AGC_PKC_PKCd_PRKCD_ST	P13796	LCP1	Q05655	PRKCD	S536	K542N	542	Missense	distal	6	no	10.011	9.948	EPSD	COSMIC	7.604	Down-regulation
AGC_PKC_PKCd_PRKCD_ST	P13796	LCP1	Q05655	PRKCD	S537	K533E	533	Missense	distal	-4	no	7.968	8.359	EPSD	COSMIC	7.604	Up-regulation
AGC_PKC_PKCd_PRKCD_ST	P13796	LCP1	Q05655	PRKCD	S537	K542N	542	Missense	distal	5	no	7.968	7.459	EPSD	COSMIC	7.604	Loss
AGC_PKC_PKCd_PRKCD_ST	P13796	LCP1	Q05655	PRKCD	S540	K533E	533	Missense	distal	-7	no	7.856	7.833	EPSD	COSMIC	7.604	Down-regulation
AGC_PKC_PKCd_PRKCD_ST	P13796	LCP1	Q05655	PRKCD	S540	S547G	547	Missense	distal	7	no	7.856	7.811	EPSD	COSMIC	7.604	Down-regulation
AGC_PKC_PKCd_PRKCD_ST	P13796	LCP1	Q05655	PRKCD	S540	K542N	542	Missense	proximal	2	no	7.856	2.482	EPSD	COSMIC	7.604	Loss
AGC_PKC_PKCd_PRKCD_ST	P13796	LCP1	Q05655	PRKCD	S547	S547G	547	Missense	central	0	yes	9.878	0.000	EPSD	COSMIC	7.604	Loss
AGC_PKC_PKCd_PRKCD_ST	P13796	LCP1	Q05655	PRKCD	S547	K542N	542	Missense	distal	-5	no	9.878	9.499	EPSD	COSMIC	7.604	Down-regulation
AGC_PKC_PKCd_PRKCD_ST	Q9HBA0	TRPV4	Q05655	PRKCD	S134	I128K	128	Missense	distal	-6	no	9.176	8.656	EPSD	COSMIC	7.604	Down-regulation
AGC_PKC_PKCd_PRKCD_ST	Q9HBA0	TRPV4	Q05655	PRKCD	S836	N833K	833	Missense	distal	-3	no	5.647	9.752	EPSD	COSMIC	7.604	Gain
AGC_PKC_PKCd_PRKCD_ST	Q13501	SQSTM1	Q05655	PRKCD	S24	R22W	22	Missense	proximal	-2	no	13.318	7.064	EPSD	COSMIC	7.604	Loss
AGC_PKC_PKCd_PRKCD_ST	Q13501	SQSTM1	Q05655	PRKCD	S284	C289Y	289	Missense	distal	5	no	8.808	8.806	EPSD	COSMIC;GDSC;CCLE	7.604	Down-regulation
AGC_PKC_PKCd_PRKCD_ST	P05787	KRT8	Q05655	PRKCD	S2	S9F	9	Missense	distal	7	no	7.619	7.571	EPSD	COSMIC	7.604	Loss
AGC_PKC_PKCd_PRKCD_ST	P05787	KRT8	Q05655	PRKCD	T6	S9F	9	Missense	distal	3	no	10.507	10.288	EPSD	COSMIC	7.604	Down-regulation
AGC_PKC_PKCd_PRKCD_ST	P05787	KRT8	Q05655	PRKCD	S9	S9F	9	Missense	central	0	yes	8.549	0.000	EPSD	COSMIC	7.604	Loss
AGC_PKC_PKCd_PRKCD_ST	P05787	KRT8	Q05655	PRKCD	S13	S9F	9	Missense	distal	-4	no	8.045	8.176	EPSD	COSMIC	7.604	Up-regulation
AGC_PKC_PKCd_PRKCD_ST	P05787	KRT8	Q05655	PRKCD	S34	S31A	31	Missense	distal	-3	no	8.274	8.510	EPSD	COSMIC	7.604	Up-regulation
AGC_PKC_PKCd_PRKCD_ST	P05787	KRT8	Q05655	PRKCD	S34	S36L	36	Missense	proximal	2	no	8.274	7.460	EPSD	COSMIC	7.604	Loss
AGC_PKC_PKCd_PRKCD_ST	P05787	KRT8	Q05655	PRKCD	S34	S31Y	31	Missense	distal	-3	no	8.274	6.971	EPSD	COSMIC	7.604	Loss
AGC_PKC_PKCd_PRKCD_ST	P05787	KRT8	Q05655	PRKCD	S34	S35F	35	Missense	proximal	1	no	8.274	8.225	EPSD	COSMIC	7.604	Down-regulation
AGC_PKC_PKCd_PRKCD_ST	P05787	KRT8	Q05655	PRKCD	S456	S449F	449	Missense	distal	-7	no	9.616	9.606	EPSD	COSMIC	7.604	Down-regulation
AGC_PKC_PKCd_PRKCD_ST	P05787	KRT8	Q05655	PRKCD	S456	S449A	449	Missense	distal	-7	no	9.616	9.610	EPSD	COSMIC	7.604	Down-regulation
AGC_PKC_PKCd_PRKCD_ST	P05787	KRT8	Q05655	PRKCD	S456	R459M	459	Missense	distal	3	no	9.616	8.487	EPSD	COSMIC	7.604	Down-regulation
AGC_PKC_PKCd_PRKCD_ST	P05787	KRT8	Q05655	PRKCD	S456	S458F	458	Missense	proximal	2	no	9.616	9.559	EPSD	COSMIC	7.604	Down-regulation
AGC_PKC_PKCd_PRKCD_ST	P05787	KRT8	Q05655	PRKCD	S456	S458T	458	Missense	proximal	2	no	9.616	9.424	EPSD	COSMIC	7.604	Down-regulation
AGC_PKC_PKCd_PRKCD_ST	P05787	KRT8	Q05655	PRKCD	S456	R454G	454	Missense	proximal	-2	no	9.616	3.852	EPSD	COSMIC	7.604	Loss
AGC_PKC_PKCd_PRKCD_ST	P05787	KRT8	Q05655	PRKCD	S457	R459M	459	Missense	proximal	2	no	13.673	7.482	EPSD	COSMIC	7.604	Loss
AGC_PKC_PKCd_PRKCD_ST	P05787	KRT8	Q05655	PRKCD	S457	S458F	458	Missense	proximal	1	no	13.673	13.623	EPSD	COSMIC	7.604	Down-regulation
AGC_PKC_PKCd_PRKCD_ST	P05787	KRT8	Q05655	PRKCD	S457	S458T	458	Missense	proximal	1	no	13.673	13.655	EPSD	COSMIC	7.604	Down-regulation
AGC_PKC_PKCd_PRKCD_ST	P05787	KRT8	Q05655	PRKCD	S457	R454G	454	Missense	distal	-3	no	13.673	8.464	EPSD	COSMIC	7.604	Down-regulation
AGC_PKC_PKCd_PRKCD_ST	P04406	GAPDH	Q05655	PRKCD	S25	T19S	19	Missense	distal	-6	no	9.327	9.287	EPSD	COSMIC	7.604	Down-regulation
AGC_PKC_PKCd_PRKCD_ST	P04406	GAPDH	Q05655	PRKCD	S192	G190S	190	Missense	proximal	-2	no	7.437	8.352	EPSD	COSMIC	7.604	Gain
AGC_PKC_PKCd_PRKCD_ST	P04406	GAPDH	Q05655	PRKCD	T237	N239K	239	Missense	proximal	2	no	4.612	9.986	EPSD	COSMIC	7.604	Gain
AGC_PKC_PKCd_PRKCD_ST	P04406	GAPDH	Q05655	PRKCD	S241	N239K	239	Missense	proximal	-2	no	4.208	8.938	EPSD	COSMIC	7.604	Gain
AGC_PKC_PKCd_PRKCD_ST	P04406	GAPDH	Q05655	PRKCD	T246	N239K	239	Missense	distal	-7	no	8.837	8.861	PhosphoSitePlus	COSMIC	7.604	Up-regulation
AGC_PKC_PKCd_PRKCD_ST	P04406	GAPDH	Q05655	PRKCD	T246	P252H	252	Missense	distal	6	no	8.837	8.825	PhosphoSitePlus	COSMIC	7.604	Down-regulation
AGC_PKC_PKCd_PRKCD_ST	P04406	GAPDH	Q05655	PRKCD	T246	D244N	244	Missense	proximal	-2	no	8.837	8.414	PhosphoSitePlus	COSMIC	7.604	Down-regulation
AGC_PKC_PKCd_PRKCD_ST	P04406	GAPDH	Q05655	PRKCD	T246	E250G	250	Missense	distal	4	no	8.837	8.771	PhosphoSitePlus	COSMIC	7.604	Down-regulation
AGC_PKC_PKCd_PRKCD_ST	P04406	GAPDH	Q05655	PRKCD	T246	R248K	248	Missense	proximal	2	no	8.837	7.660	PhosphoSitePlus	COSMIC	7.604	Down-regulation
AGC_PKC_PKCd_PRKCD_ST	P04406	GAPDH	Q05655	PRKCD	S321	R323K	323	Missense	proximal	2	no	9.907	8.730	EPSD	COSMIC	7.604	Down-regulation
AGC_PKC_PKCd_PRKCD_ST	P04406	GAPDH	Q05655	PRKCD	S321	V324M	324	Missense	distal	3	no	9.907	9.933	EPSD	COSMIC	7.604	Up-regulation
AGC_PKC_PKCd_PRKCD_ST	P04406	GAPDH	Q05655	PRKCD	S321	S321R	321	Missense	central	0	yes	9.907	0.000	EPSD	COSMIC	7.604	Loss
AGC_PKC_PKCd_PRKCD_ST	Q02297	NRG1	Q05655	PRKCD	S26	G21R	21	Missense	distal	-5	no	7.499	7.912	EPSD	COSMIC	7.604	Gain
AGC_PKC_PKCd_PRKCD_ST	Q02297	NRG1	Q05655	PRKCD	S281	R277S	277	Missense	distal	-4	no	16.002	16.235	EPSD	COSMIC	7.604	Up-regulation
AGC_PKC_PKCd_PRKCD_ST	Q02297	NRG1	Q05655	PRKCD	S281	R286Q	286	Missense	distal	5	no	16.002	15.668	EPSD	COSMIC	7.604	Down-regulation
AGC_PKC_PKCd_PRKCD_ST	Q02297	NRG1	Q05655	PRKCD	S281	R279W	279	Missense	proximal	-2	no	16.002	9.749	EPSD	COSMIC;CCLE	7.604	Down-regulation
AGC_PKC_PKCd_PRKCD_ST	Q02297	NRG1	Q05655	PRKCD	S281	L282F	282	Missense	proximal	1	no	16.002	16.008	EPSD	COSMIC	7.604	Up-regulation
AGC_PKC_PKCd_PRKCD_ST	Q02297	NRG1	Q05655	PRKCD	S281	R283L	283	Missense	proximal	2	no	16.002	9.125	EPSD	COSMIC	7.604	Down-regulation
AGC_PKC_PKCd_PRKCD_ST	Q02297	NRG1	Q05655	PRKCD	S281	E285D	285	Missense	distal	4	no	16.002	15.977	EPSD	COSMIC	7.604	Down-regulation
AGC_PKC_PKCd_PRKCD_ST	Q02297	NRG1	Q05655	PRKCD	S281	D276E	276	Missense	distal	-5	no	16.002	16.000	EPSD	COSMIC	7.604	Down-regulation
AGC_PKC_PKCd_PRKCD_ST	Q02297	NRG1	Q05655	PRKCD	S281	R277H	277	Missense	distal	-4	no	16.002	16.295	EPSD	COSMIC	7.604	Up-regulation
AGC_PKC_PKCd_PRKCD_ST	Q02297	NRG1	Q05655	PRKCD	S281	R283Q	283	Missense	proximal	2	no	16.002	9.213	EPSD	COSMIC;CCLE	7.604	Down-regulation
AGC_PKC_PKCd_PRKCD_ST	Q02297	NRG1	Q05655	PRKCD	S281	R279Q	279	Missense	proximal	-2	no	16.002	10.568	EPSD	COSMIC	7.604	Down-regulation
AGC_PKC_PKCd_PRKCD_ST	Q02297	NRG1	Q05655	PRKCD	S284	R277S	277	Missense	distal	-7	no	9.961	9.950	EPSD	COSMIC	7.604	Down-regulation
AGC_PKC_PKCd_PRKCD_ST	Q02297	NRG1	Q05655	PRKCD	S284	R286Q	286	Missense	proximal	2	no	9.961	3.172	EPSD	COSMIC	7.604	Loss
AGC_PKC_PKCd_PRKCD_ST	Q02297	NRG1	Q05655	PRKCD	S284	R279W	279	Missense	distal	-5	no	9.961	9.416	EPSD	COSMIC;CCLE	7.604	Down-regulation
AGC_PKC_PKCd_PRKCD_ST	Q02297	NRG1	Q05655	PRKCD	S284	L282F	282	Missense	proximal	-2	no	9.961	10.722	EPSD	COSMIC	7.604	Up-regulation
AGC_PKC_PKCd_PRKCD_ST	Q02297	NRG1	Q05655	PRKCD	S284	R283L	283	Missense	proximal	-1	no	9.961	9.770	EPSD	COSMIC	7.604	Down-regulation
AGC_PKC_PKCd_PRKCD_ST	Q02297	NRG1	Q05655	PRKCD	S284	E285D	285	Missense	proximal	1	no	9.961	9.933	EPSD	COSMIC	7.604	Down-regulation
AGC_PKC_PKCd_PRKCD_ST	Q02297	NRG1	Q05655	PRKCD	S284	R277H	277	Missense	distal	-7	no	9.961	9.944	EPSD	COSMIC	7.604	Down-regulation
AGC_PKC_PKCd_PRKCD_ST	Q02297	NRG1	Q05655	PRKCD	S284	R283Q	283	Missense	proximal	-1	no	9.961	9.825	EPSD	COSMIC;CCLE	7.604	Down-regulation
AGC_PKC_PKCd_PRKCD_ST	Q02297	NRG1	Q05655	PRKCD	S284	R279Q	279	Missense	distal	-5	no	9.961	9.611	EPSD	COSMIC	7.604	Down-regulation
AGC_PKC_PKCd_PRKCD_ST	Q02297	NRG1	Q05655	PRKCD	S284	S281T	281	Missense	distal	-3	no	9.961	9.444	EPSD	COSMIC	7.604	Down-regulation
AGC_PKC_PKCd_PRKCD_ST	Q02297	NRG1	Q05655	PRKCD	S414	S414Y	414	Missense	central	0	yes	8.331	0.000	EPSD	COSMIC	7.604	Loss
AGC_PKC_PKCd_PRKCD_ST	Q02297	NRG1	Q05655	PRKCD	S414	T411S	411	Missense	distal	-3	no	8.331	8.848	EPSD	COSMIC	7.604	Up-regulation
AGC_PKC_PKCd_PRKCD_ST	Q02297	NRG1	Q05655	PRKCD	S414	D413E	413	Missense	proximal	-1	no	8.331	8.312	EPSD	COSMIC	7.604	Down-regulation
AGC_PKC_PKCd_PRKCD_ST	Q02297	NRG1	Q05655	PRKCD	S414	R409G	409	Missense	distal	-5	no	8.331	7.918	EPSD	COSMIC	7.604	Down-regulation
AGC_PKC_PKCd_PRKCD_ST	Q02297	NRG1	Q05655	PRKCD	S414	R416Q	416	Missense	proximal	2	no	8.331	1.541	EPSD	COSMIC	7.604	Loss
AGC_PKC_PKCd_PRKCD_ST	Q02297	NRG1	Q05655	PRKCD	S414	P419L	419	Missense	distal	5	no	8.331	8.108	EPSD	COSMIC	7.604	Down-regulation
AGC_PKC_PKCd_PRKCD_ST	Q02297	NRG1	Q05655	PRKCD	S414	T411A	411	Missense	distal	-3	no	8.331	9.084	EPSD	COSMIC;CCLE	7.604	Up-regulation
AGC_PKC_PKCd_PRKCD_ST	Q02297	NRG1	Q05655	PRKCD	S414	H407R	407	Missense	distal	-7	no	8.331	8.348	EPSD	COSMIC	7.604	Up-regulation
AGC_PKC_PKCd_PRKCD_ST	Q02297	NRG1	Q05655	PRKCD	S414	D413N	413	Missense	proximal	-1	no	8.331	8.305	EPSD	COSMIC	7.604	Down-regulation
AGC_PKC_PKCd_PRKCD_ST	Q02297	NRG1	Q05655	PRKCD	S414	S414F	414	Missense	central	0	yes	8.331	0.000	EPSD	COSMIC	7.604	Loss
AGC_PKC_PKCd_PRKCD_ST	Q02297	NRG1	Q05655	PRKCD	S418	S414Y	414	Missense	distal	-4	no	8.125	8.346	EPSD	COSMIC	7.604	Up-regulation
AGC_PKC_PKCd_PRKCD_ST	Q02297	NRG1	Q05655	PRKCD	S418	T411S	411	Missense	distal	-7	no	8.125	8.129	EPSD	COSMIC	7.604	Up-regulation
AGC_PKC_PKCd_PRKCD_ST	Q02297	NRG1	Q05655	PRKCD	S418	D413E	413	Missense	distal	-5	no	8.125	8.122	EPSD	COSMIC	7.604	Down-regulation
AGC_PKC_PKCd_PRKCD_ST	Q02297	NRG1	Q05655	PRKCD	S418	R416Q	416	Missense	proximal	-2	no	8.125	2.690	EPSD	COSMIC	7.604	Loss
AGC_PKC_PKCd_PRKCD_ST	Q02297	NRG1	Q05655	PRKCD	S418	P419L	419	Missense	proximal	1	no	8.125	8.050	EPSD	COSMIC	7.604	Down-regulation
AGC_PKC_PKCd_PRKCD_ST	Q02297	NRG1	Q05655	PRKCD	S418	T411A	411	Missense	distal	-7	no	8.125	8.123	EPSD	COSMIC;CCLE	7.604	Down-regulation
AGC_PKC_PKCd_PRKCD_ST	Q02297	NRG1	Q05655	PRKCD	S418	D413N	413	Missense	distal	-5	no	8.125	8.101	EPSD	COSMIC	7.604	Down-regulation
AGC_PKC_PKCd_PRKCD_ST	Q02297	NRG1	Q05655	PRKCD	S418	S414F	414	Missense	distal	-4	no	8.125	8.255	EPSD	COSMIC	7.604	Up-regulation
AGC_PKC_PKCd_PRKCD_ST	Q02297	NRG1	Q05655	PRKCD	S435	T441K	441	Missense	distal	6	no	9.417	9.459	EPSD	COSMIC	7.604	Up-regulation
AGC_PKC_PKCd_PRKCD_ST	Q02297	NRG1	Q05655	PRKCD	S435	R433H	433	Missense	proximal	-2	no	9.417	4.442	EPSD	COSMIC	7.604	Loss
AGC_PKC_PKCd_PRKCD_ST	Q02297	NRG1	Q05655	PRKCD	S435	D438N	438	Missense	distal	3	no	9.417	9.393	EPSD	COSMIC	7.604	Down-regulation
AGC_PKC_PKCd_PRKCD_ST	Q02297	NRG1	Q05655	PRKCD	S435	P431L	431	Missense	distal	-4	no	9.417	9.556	EPSD	COSMIC	7.604	Up-regulation
AGC_PKC_PKCd_PRKCD_ST	Q02297	NRG1	Q05655	PRKCD	S435	R433C	433	Missense	proximal	-2	no	9.417	3.423	EPSD	COSMIC	7.604	Loss
AGC_PKC_PKCd_PRKCD_ST	Q02297	NRG1	Q05655	PRKCD	S435	M428I	428	Missense	distal	-7	no	9.417	9.415	EPSD	COSMIC	7.604	Down-regulation
AGC_PKC_PKCd_PRKCD_ST	Q02297	NRG1	Q05655	PRKCD	S443	T441K	441	Missense	proximal	-2	no	3.729	8.447	EPSD	COSMIC	7.604	Gain
AGC_PKC_PKCd_PRKCD_ST	Q02297	NRG1	Q05655	PRKCD	S444	S444L	444	Missense	central	0	yes	7.895	0.000	EPSD	COSMIC	7.604	Loss
AGC_PKC_PKCd_PRKCD_ST	Q02297	NRG1	Q05655	PRKCD	S444	S447L	447	Missense	distal	3	no	7.895	7.608	EPSD	COSMIC	7.604	Down-regulation
AGC_PKC_PKCd_PRKCD_ST	Q02297	NRG1	Q05655	PRKCD	S444	S450Y	450	Missense	distal	6	no	7.895	7.854	EPSD	COSMIC	7.604	Down-regulation
AGC_PKC_PKCd_PRKCD_ST	Q02297	NRG1	Q05655	PRKCD	S444	P445S	445	Missense	proximal	1	no	7.895	7.876	EPSD	COSMIC	7.604	Down-regulation
AGC_PKC_PKCd_PRKCD_ST	Q02297	NRG1	Q05655	PRKCD	S444	P445H	445	Missense	proximal	1	no	7.895	7.835	EPSD	COSMIC	7.604	Down-regulation
AGC_PKC_PKCd_PRKCD_ST	Q02297	NRG1	Q05655	PRKCD	S444	T441K	441	Missense	distal	-3	no	7.895	11.952	EPSD	COSMIC	7.604	Up-regulation
AGC_PKC_PKCd_PRKCD_ST	Q02297	NRG1	Q05655	PRKCD	S444	D438N	438	Missense	distal	-6	no	7.895	7.942	EPSD	COSMIC	7.604	Up-regulation
AGC_PKC_PKCd_PRKCD_ST	Q02297	NRG1	Q05655	PRKCD	S444	P448H	448	Missense	distal	4	no	7.895	7.783	EPSD	COSMIC	7.604	Down-regulation
AGC_PKC_PKCd_PRKCD_ST	Q02297	NRG1	Q05655	PRKCD	S444	P448S	448	Missense	distal	4	no	7.895	7.857	EPSD	COSMIC	7.604	Down-regulation
AGC_PKC_PKCd_PRKCD_ST	Q02297	NRG1	Q05655	PRKCD	S444	S450L	450	Missense	distal	6	no	7.895	7.865	EPSD	COSMIC	7.604	Down-regulation
AGC_PKC_PKCd_PRKCD_ST	Q02297	NRG1	Q05655	PRKCD	S619	G616V	616	Missense	distal	-3	no	7.893	8.301	EPSD	COSMIC	7.604	Up-regulation
AGC_PKC_PKCd_PRKCD_ST	Q02297	NRG1	Q05655	PRKCD	S619	S619L	619	Missense	central	0	yes	7.893	0.000	EPSD	COSMIC	7.604	Loss
AGC_PKC_PKCd_PRKCD_ST	Q02297	NRG1	Q05655	PRKCD	S619	P614T	614	Missense	distal	-5	no	7.893	7.877	EPSD	COSMIC	7.604	Down-regulation
AGC_PKC_PKCd_PRKCD_ST	Q02297	NRG1	Q05655	PRKCD	S619	I624F	624	Missense	distal	5	no	7.893	8.016	EPSD	COSMIC	7.604	Up-regulation
AGC_PKC_PKCd_PRKCD_ST	Q02297	NRG1	Q05655	PRKCD	S619	E623K	623	Missense	distal	4	no	7.893	8.487	EPSD	COSMIC	7.604	Up-regulation
AGC_PKC_PKCd_PRKCD_ST	Q02297	NRG1	Q05655	PRKCD	S619	E623D	623	Missense	distal	4	no	7.893	7.867	EPSD	COSMIC	7.604	Down-regulation
AGC_PKC_PKCd_PRKCD_ST	Q02297	NRG1	Q05655	PRKCD	S619	F618L	618	Missense	proximal	-1	no	7.893	7.884	EPSD	COSMIC	7.604	Down-regulation
AGC_PKC_PKCd_PRKCD_ST	P51398	DAP3	Q05655	PRKCD	S215	W210C	210	Missense	distal	-5	no	11.775	11.843	EPSD	COSMIC	7.604	Up-regulation
AGC_PKC_PKCd_PRKCD_ST	P51398	DAP3	Q05655	PRKCD	S215	R213T	213	Missense	proximal	-2	no	11.775	5.812	EPSD	COSMIC	7.604	Loss
AGC_PKC_PKCd_PRKCD_ST	P51398	DAP3	Q05655	PRKCD	T216	W210C	210	Missense	distal	-6	no	10.214	10.092	EPSD	COSMIC	7.604	Down-regulation
AGC_PKC_PKCd_PRKCD_ST	P51398	DAP3	Q05655	PRKCD	T216	R213T	213	Missense	distal	-3	no	10.214	5.122	EPSD	COSMIC	7.604	Loss
AGC_PKC_PKCd_PRKCD_ST	P51398	DAP3	Q05655	PRKCD	S251	S252F	252	Missense	proximal	1	no	10.259	10.210	EPSD	COSMIC	7.604	Down-regulation
AGC_PKC_PKCd_PRKCD_ST	P51398	DAP3	Q05655	PRKCD	T273	A267V	267	Missense	distal	-6	no	11.344	11.468	EPSD	COSMIC	7.604	Up-regulation
AGC_PKC_PKCd_PRKCD_ST	P42224	STAT1	Q05655	PRKCD	T373	T373K	373	Missense	central	0	yes	11.393	0.000	EPSD	COSMIC	7.604	Loss
AGC_PKC_PKCd_PRKCD_ST	P42224	STAT1	Q05655	PRKCD	T373	K366N	366	Missense	distal	-7	no	11.393	11.369	EPSD	COSMIC	7.604	Down-regulation
AGC_PKC_PKCd_PRKCD_ST	P42224	STAT1	Q05655	PRKCD	S604	R608Q	608	Missense	distal	4	no	9.193	8.605	EPSD	COSMIC	7.604	Down-regulation
AGC_PKC_PKCd_PRKCD_ST	P42224	STAT1	Q05655	PRKCD	S606	R608Q	608	Missense	proximal	2	no	9.555	2.765	EPSD	COSMIC	7.604	Loss
AGC_PKC_PKCd_PRKCD_ST	P42224	STAT1	Q05655	PRKCD	T635	E632K	632	Missense	distal	-3	no	3.973	8.358	EPSD	COSMIC	7.604	Gain
AGC_PKC_PKCd_PRKCD_ST	P62753	RPS6	Q05655	PRKCD	T181	I176V	176	Missense	distal	-5	no	10.627	10.665	EPSD	COSMIC	7.604	Up-regulation
AGC_PKC_PKCd_PRKCD_ST	P62753	RPS6	Q05655	PRKCD	T181	V184L	184	Missense	distal	3	no	10.627	10.638	EPSD	COSMIC	7.604	Up-regulation
AGC_PKC_PKCd_PRKCD_ST	Q14247	CTTN	Q05655	PRKCD	S150	G143W	143	Missense	distal	-7	no	13.265	13.254	EPSD	COSMIC	7.604	Down-regulation
AGC_PKC_PKCd_PRKCD_ST	Q14247	CTTN	Q05655	PRKCD	S187	D190N	190	Missense	distal	3	no	13.982	13.957	EPSD	COSMIC	7.604	Down-regulation
AGC_PKC_PKCd_PRKCD_ST	Q14247	CTTN	Q05655	PRKCD	S224	S224F	224	Missense	central	0	yes	12.196	0.000	EPSD	COSMIC	7.604	Loss
AGC_PKC_PKCd_PRKCD_ST	Q14247	CTTN	Q05655	PRKCD	S261	S261F	261	Missense	central	0	yes	8.469	0.000	EPSD	COSMIC	7.604	Loss
AGC_PKC_PKCd_PRKCD_ST	Q14247	CTTN	Q05655	PRKCD	S277	R279W	279	Missense	proximal	2	no	9.333	2.660	EPSD	COSMIC	7.604	Loss
AGC_PKC_PKCd_PRKCD_ST	Q14247	CTTN	Q05655	PRKCD	S277	G274E	274	Missense	distal	-3	no	9.333	9.121	EPSD	COSMIC	7.604	Down-regulation
AGC_PKC_PKCd_PRKCD_ST	Q14247	CTTN	Q05655	PRKCD	S277	G274W	274	Missense	distal	-3	no	9.333	9.246	EPSD	COSMIC	7.604	Down-regulation
AGC_PKC_PKCd_PRKCD_ST	Q14247	CTTN	Q05655	PRKCD	S277	G274A	274	Missense	distal	-3	no	9.333	10.203	EPSD	COSMIC	7.604	Up-regulation
AGC_PKC_PKCd_PRKCD_ST	Q14247	CTTN	Q05655	PRKCD	S277	G270E	270	Missense	distal	-7	no	9.333	9.335	EPSD	COSMIC;CCLE	7.604	Up-regulation
AGC_PKC_PKCd_PRKCD_ST	Q14247	CTTN	Q05655	PRKCD	S277	S277L	277	Missense	central	0	yes	9.333	0.000	EPSD	COSMIC	7.604	Loss
AGC_PKC_PKCd_PRKCD_ST	Q14247	CTTN	Q05655	PRKCD	S282	R279W	279	Missense	distal	-3	no	8.343	3.046	EPSD	COSMIC	7.604	Loss
AGC_PKC_PKCd_PRKCD_ST	Q14247	CTTN	Q05655	PRKCD	S282	F287L	287	Missense	distal	5	no	8.343	8.363	EPSD	COSMIC	7.604	Up-regulation
AGC_PKC_PKCd_PRKCD_ST	Q14247	CTTN	Q05655	PRKCD	S282	S277L	277	Missense	distal	-5	no	8.343	8.187	EPSD	COSMIC	7.604	Down-regulation
AGC_PKC_PKCd_PRKCD_ST	Q14247	CTTN	Q05655	PRKCD	S348	R351T	351	Missense	distal	3	no	8.086	7.087	EPSD	COSMIC	7.604	Loss
AGC_PKC_PKCd_PRKCD_ST	P98082	DAB2	Q05655	PRKCD	S24	K26M	26	Missense	proximal	2	no	12.739	7.725	PhosphoSitePlus	COSMIC	7.604	Down-regulation
AGC_PKC_PKCd_PRKCD_ST	P98082	DAB2	Q05655	PRKCD	S24	P23L	23	Missense	proximal	-1	no	12.739	12.663	PhosphoSitePlus	COSMIC	7.604	Down-regulation
AGC_PKC_PKCd_PRKCD_ST	P98082	DAB2	Q05655	PRKCD	S24	G31V	31	Missense	distal	7	no	12.739	12.720	PhosphoSitePlus	COSMIC	7.604	Down-regulation
AGC_PKC_PKCd_PRKCD_ST	P98082	DAB2	Q05655	PRKCD	S24	A18S	18	Missense	distal	-6	no	12.739	12.621	PhosphoSitePlus	COSMIC	7.604	Down-regulation
AGC_PKC_PKCd_PRKCD_ST	P98082	DAB2	Q05655	PRKCD	S249	E252Q	252	Missense	distal	3	no	8.261	8.358	EPSD	COSMIC	7.604	Up-regulation
AGC_PKC_PKCd_PRKCD_ST	P98082	DAB2	Q05655	PRKCD	S313	F311L	311	Missense	proximal	-2	no	9.632	8.871	EPSD	COSMIC;CCLE	7.604	Down-regulation
AGC_PKC_PKCd_PRKCD_ST	P98082	DAB2	Q05655	PRKCD	S313	Q319P	319	Missense	distal	6	no	9.632	9.640	EPSD	COSMIC	7.604	Up-regulation
AGC_PKC_PKCd_PRKCD_ST	P98082	DAB2	Q05655	PRKCD	S313	T307A	307	Missense	distal	-6	no	9.632	9.709	EPSD	COSMIC	7.604	Up-regulation
AGC_PKC_PKCd_PRKCD_ST	P98082	DAB2	Q05655	PRKCD	S368	Q370K	370	Missense	proximal	2	no	2.976	8.588	EPSD	COSMIC	7.604	Gain
AGC_PKC_PKCd_PRKCD_ST	P98082	DAB2	Q05655	PRKCD	S436	G440R	440	Missense	distal	4	no	10.180	10.847	EPSD	COSMIC	7.604	Up-regulation
AGC_PKC_PKCd_PRKCD_ST	P98082	DAB2	Q05655	PRKCD	S436	I431M	431	Missense	distal	-5	no	10.180	10.217	EPSD	COSMIC	7.604	Up-regulation
AGC_PKC_PKCd_PRKCD_ST	P98082	DAB2	Q05655	PRKCD	S436	G442D	442	Missense	distal	6	no	10.180	10.186	EPSD	COSMIC	7.604	Up-regulation
AGC_PKC_PKCd_PRKCD_ST	P98082	DAB2	Q05655	PRKCD	S436	R443W	443	Missense	distal	7	no	10.180	10.014	EPSD	COSMIC	7.604	Down-regulation
AGC_PKC_PKCd_PRKCD_ST	P98082	DAB2	Q05655	PRKCD	S436	R443L	443	Missense	distal	7	no	10.180	10.057	EPSD	COSMIC	7.604	Down-regulation
AGC_PKC_PKCd_PRKCD_ST	P98082	DAB2	Q05655	PRKCD	S723	Q721K	721	Missense	proximal	-2	no	7.502	11.691	EPSD	COSMIC	7.604	Gain
AGC_PKC_PKCd_PRKCD_ST	P98082	DAB2	Q05655	PRKCD	S723	Q721H	721	Missense	proximal	-2	no	7.502	7.961	EPSD	COSMIC	7.604	Gain
AGC_PKC_PKCd_PRKCD_ST	P98082	DAB2	Q05655	PRKCD	S742	P737S	737	Missense	distal	-5	no	7.927	7.936	EPSD	COSMIC	7.604	Up-regulation
AGC_PKC_PKCd_PRKCD_ST	P98082	DAB2	Q05655	PRKCD	S742	N736T	736	Missense	distal	-6	no	7.927	7.768	EPSD	COSMIC	7.604	Down-regulation
AGC_PKC_PKCd_PRKCD_ST	P98082	DAB2	Q05655	PRKCD	S742	S749F	749	Missense	distal	7	no	7.927	7.879	EPSD	COSMIC	7.604	Down-regulation
AGC_PKC_PKCd_PRKCD_ST	Q9Y2R2	PTPN22	Q05655	PRKCD	S35	S35F	35	Missense	central	0	yes	18.769	0.000	PhosphoSitePlus	COSMIC	7.604	Loss
AGC_PKC_PKCd_PRKCD_ST	Q9Y2R2	PTPN22	Q05655	PRKCD	S35	K32E	32	Missense	distal	-3	no	18.769	14.384	PhosphoSitePlus	COSMIC	7.604	Down-regulation
AGC_PKC_PKCd_PRKCD_ST	Q9Y2R2	PTPN22	Q05655	PRKCD	S167	E163K	163	Missense	distal	-4	no	9.951	9.560	EPSD	COSMIC	7.604	Down-regulation
AGC_PKC_PKCd_PRKCD_ST	Q9Y2R2	PTPN22	Q05655	PRKCD	S167	E163G	163	Missense	distal	-4	no	9.951	9.970	EPSD	COSMIC	7.604	Up-regulation
AGC_PKC_PKCd_PRKCD_ST	Q9Y2R2	PTPN22	Q05655	PRKCD	S167	K164N	164	Missense	distal	-3	no	9.951	5.847	EPSD	COSMIC	7.604	Loss
AGC_PKC_PKCd_PRKCD_ST	Q9Y2R2	PTPN22	Q05655	PRKCD	S692	D689N	689	Missense	distal	-3	no	9.496	9.396	EPSD	COSMIC;GDSC;CCLE	7.604	Down-regulation
AGC_PKC_PKCd_PRKCD_ST	Q9Y2R2	PTPN22	Q05655	PRKCD	S692	R690H	690	Missense	proximal	-2	no	9.496	4.520	EPSD	COSMIC	7.604	Loss
AGC_PKC_PKCd_PRKCD_ST	Q9Y2R2	PTPN22	Q05655	PRKCD	S692	P698S	698	Missense	distal	6	no	9.496	9.502	EPSD	COSMIC	7.604	Up-regulation
AGC_PKC_PKCd_PRKCD_ST	Q9Y2R2	PTPN22	Q05655	PRKCD	S751	K750T	750	Missense	proximal	-1	no	11.808	11.679	EPSD	COSMIC	7.604	Down-regulation
AGC_PKC_PKCd_PRKCD_ST	Q9Y2R2	PTPN22	Q05655	PRKCD	S751	R748T	748	Missense	distal	-3	no	11.808	6.716	EPSD	COSMIC	7.604	Loss
AGC_PKC_PKCd_PRKCD_ST	Q9Y2R2	PTPN22	Q05655	PRKCD	S751	S749N	749	Missense	proximal	-2	no	11.808	10.682	EPSD	COSMIC	7.604	Down-regulation
AGC_PKC_PKCd_PRKCD_ST	Q9Y2R2	PTPN22	Q05655	PRKCD	S793	G797R	797	Missense	distal	4	no	10.199	10.866	EPSD	COSMIC	7.604	Up-regulation
AGC_PKC_PKCd_PRKCD_ST	Q9Y2R2	PTPN22	Q05655	PRKCD	S793	P795A	795	Missense	proximal	2	no	10.199	10.794	EPSD	COSMIC	7.604	Up-regulation
AGC_PKC_PKCd_PRKCD_ST	Q9Y2R2	PTPN22	Q05655	PRKCD	S793	G797E	797	Missense	distal	4	no	10.199	10.264	EPSD	COSMIC	7.604	Up-regulation
AGC_PKC_PKCd_PRKCD_ST	Q9Y2R2	PTPN22	Q05655	PRKCD	S793	R799G	799	Missense	distal	6	no	10.199	10.140	EPSD	COSMIC	7.604	Down-regulation
AGC_PKC_PKCd_PRKCD_ST	Q15139	PRKD1	Q05655	PRKCD	S153	P146T	146	Missense	distal	-7	no	11.018	11.014	EPSD	COSMIC	7.604	Down-regulation
AGC_PKC_PKCd_PRKCD_ST	Q15139	PRKD1	Q05655	PRKCD	S153	A158V	158	Missense	distal	5	no	11.018	10.897	EPSD	COSMIC	7.604	Down-regulation
AGC_PKC_PKCd_PRKCD_ST	Q15139	PRKD1	Q05655	PRKCD	S153	H152Y	152	Missense	proximal	-1	no	11.018	10.943	EPSD	COSMIC	7.604	Down-regulation
AGC_PKC_PKCd_PRKCD_ST	Q15139	PRKD1	Q05655	PRKCD	S153	P146L	146	Missense	distal	-7	no	11.018	11.007	EPSD	COSMIC	7.604	Down-regulation
AGC_PKC_PKCd_PRKCD_ST	Q15139	PRKD1	Q05655	PRKCD	S153	R155K	155	Missense	proximal	2	no	11.018	9.841	EPSD	COSMIC	7.604	Down-regulation
AGC_PKC_PKCd_PRKCD_ST	Q15139	PRKD1	Q05655	PRKCD	S205	R201Q	201	Missense	distal	-4	no	14.171	14.487	EPSD	COSMIC;GDSC;CCLE	7.604	Up-regulation
AGC_PKC_PKCd_PRKCD_ST	Q15139	PRKD1	Q05655	PRKCD	S205	R200K	200	Missense	distal	-5	no	14.171	14.146	EPSD	COSMIC	7.604	Down-regulation
AGC_PKC_PKCd_PRKCD_ST	Q15139	PRKD1	Q05655	PRKCD	S397	R394K	394	Missense	distal	-3	no	8.054	7.019	EPSD	COSMIC	7.604	Loss
AGC_PKC_PKCd_PRKCD_ST	Q15139	PRKD1	Q05655	PRKCD	S397	S397N	397	Missense	central	0	yes	8.054	0.000	EPSD	COSMIC	7.604	Loss
AGC_PKC_PKCd_PRKCD_ST	Q15139	PRKD1	Q05655	PRKCD	S397	N402T	402	Missense	distal	5	no	8.054	8.175	EPSD	COSMIC	7.604	Up-regulation
AGC_PKC_PKCd_PRKCD_ST	Q15139	PRKD1	Q05655	PRKCD	S412	S412F	412	Missense	central	0	yes	8.277	0.000	EPSD;PhosphoSitePlus	COSMIC	7.604	Loss
AGC_PKC_PKCd_PRKCD_ST	Q15139	PRKD1	Q05655	PRKCD	S412	Q411H	411	Missense	proximal	-1	no	8.277	8.268	EPSD;PhosphoSitePlus	COSMIC	7.604	Down-regulation
AGC_PKC_PKCd_PRKCD_ST	Q15139	PRKD1	Q05655	PRKCD	S412	V413D	413	Missense	proximal	1	no	8.277	8.296	EPSD;PhosphoSitePlus	COSMIC	7.604	Up-regulation
AGC_PKC_PKCd_PRKCD_ST	Q15139	PRKD1	Q05655	PRKCD	S412	Q411L	411	Missense	proximal	-1	no	8.277	8.222	EPSD;PhosphoSitePlus	COSMIC	7.604	Down-regulation
AGC_PKC_PKCd_PRKCD_ST	Q15139	PRKD1	Q05655	PRKCD	S420	V413D	413	Missense	distal	-7	no	11.256	11.261	EPSD	COSMIC	7.604	Up-regulation
AGC_PKC_PKCd_PRKCD_ST	Q15139	PRKD1	Q05655	PRKCD	S420	S420F	420	Missense	central	0	yes	11.256	0.000	EPSD	COSMIC	7.604	Loss
AGC_PKC_PKCd_PRKCD_ST	Q15139	PRKD1	Q05655	PRKCD	S421	S420F	420	Missense	proximal	-1	no	10.023	9.916	EPSD	COSMIC	7.604	Down-regulation
AGC_PKC_PKCd_PRKCD_ST	Q15139	PRKD1	Q05655	PRKCD	S738	G735V	735	Missense	distal	-3	no	8.804	9.212	EPSD;PhosphoSitePlus	COSMIC	7.604	Up-regulation
AGC_PKC_PKCd_PRKCD_ST	Q15139	PRKD1	Q05655	PRKCD	S738	V743L	743	Missense	distal	5	no	8.804	8.871	EPSD;PhosphoSitePlus	COSMIC	7.604	Up-regulation
AGC_PKC_PKCd_PRKCD_ST	Q15139	PRKD1	Q05655	PRKCD	S738	A731D	731	Missense	distal	-7	no	8.804	8.803	EPSD;PhosphoSitePlus	COSMIC	7.604	Down-regulation
AGC_PKC_PKCd_PRKCD_ST	Q15139	PRKD1	Q05655	PRKCD	S742	A748T	748	Missense	distal	6	no	9.075	9.086	PhosphoSitePlus;EPSD	COSMIC	7.604	Up-regulation
AGC_PKC_PKCd_PRKCD_ST	Q15139	PRKD1	Q05655	PRKCD	S742	G735V	735	Missense	distal	-7	no	9.075	9.073	PhosphoSitePlus;EPSD	COSMIC	7.604	Down-regulation
AGC_PKC_PKCd_PRKCD_ST	Q15139	PRKD1	Q05655	PRKCD	S742	V743L	743	Missense	proximal	1	no	9.075	9.116	PhosphoSitePlus;EPSD	COSMIC	7.604	Up-regulation
AGC_PKC_PKCd_PRKCD_ST	Q15139	PRKD1	Q05655	PRKCD	S742	T746I	746	Missense	distal	4	no	9.075	8.823	PhosphoSitePlus;EPSD	COSMIC	7.604	Down-regulation
AGC_PKC_PKCd_PRKCD_ST	Q15139	PRKD1	Q05655	PRKCD	S829	Y828H	828	Missense	proximal	-1	no	11.806	11.881	EPSD	COSMIC	7.604	Up-regulation
AGC_PKC_PKCd_PRKCD_ST	P05230	FGF1	Q05655	PRKCD	S131	L126F	126	Missense	distal	-5	no	12.592	12.638	PhosphoSitePlus	COSMIC	7.604	Up-regulation
AGC_PKC_PKCd_PRKCD_ST	P05230	FGF1	Q05655	PRKCD	S131	G135S	135	Missense	distal	4	no	12.592	12.790	PhosphoSitePlus	COSMIC	7.604	Up-regulation
AGC_PKC_PKCd_PRKCD_ST	P05230	FGF1	Q05655	PRKCD	S131	R134C	134	Missense	distal	3	no	12.592	11.317	PhosphoSitePlus	COSMIC	7.604	Down-regulation
AGC_PKC_PKCd_PRKCD_ST	P17405	SMPD1	Q05655	PRKCD	S7	R3H	3	Missense	distal	-4	no	8.709	9.002	EPSD	COSMIC	7.604	Up-regulation
AGC_PKC_PKCd_PRKCD_ST	P17405	SMPD1	Q05655	PRKCD	S231	P235L	235	Missense	distal	4	no	13.087	12.883	EPSD	COSMIC	7.604	Down-regulation
AGC_PKC_PKCd_PRKCD_ST	P17405	SMPD1	Q05655	PRKCD	S231	R229H	229	Missense	proximal	-2	no	13.087	8.112	EPSD	COSMIC	7.604	Down-regulation
AGC_PKC_PKCd_PRKCD_ST	P17405	SMPD1	Q05655	PRKCD	S231	R229C	229	Missense	proximal	-2	no	13.087	7.093	EPSD	COSMIC	7.604	Loss
AGC_PKC_PKCd_PRKCD_ST	P28329	CHAT	Q05655	PRKCD	T373	R375Q	375	Missense	proximal	2	no	8.955	2.166	EPSD	COSMIC	7.604	Loss
AGC_PKC_PKCd_PRKCD_ST	P28329	CHAT	Q05655	PRKCD	T373	K370R	370	Missense	distal	-3	no	8.955	9.991	EPSD	COSMIC	7.604	Up-regulation
AGC_PKC_PKCd_PRKCD_ST	P28329	CHAT	Q05655	PRKCD	T373	T366M	366	Missense	distal	-7	no	8.955	8.948	EPSD	COSMIC	7.604	Down-regulation
AGC_PKC_PKCd_PRKCD_ST	P28329	CHAT	Q05655	PRKCD	T373	V369M	369	Missense	distal	-4	no	8.955	8.949	EPSD	COSMIC	7.604	Down-regulation
AGC_PKC_PKCd_PRKCD_ST	P28329	CHAT	Q05655	PRKCD	T373	D376G	376	Missense	distal	3	no	8.955	8.922	EPSD	COSMIC	7.604	Down-regulation
AGC_PKC_PKCd_PRKCD_ST	P28329	CHAT	Q05655	PRKCD	S377	R375Q	375	Missense	proximal	-2	no	8.071	2.636	EPSD	COSMIC	7.604	Loss
AGC_PKC_PKCd_PRKCD_ST	P28329	CHAT	Q05655	PRKCD	S377	R383S	383	Missense	distal	6	no	8.071	8.038	EPSD	COSMIC	7.604	Down-regulation
AGC_PKC_PKCd_PRKCD_ST	P28329	CHAT	Q05655	PRKCD	S377	K370R	370	Missense	distal	-7	no	8.071	8.069	EPSD	COSMIC	7.604	Down-regulation
AGC_PKC_PKCd_PRKCD_ST	P28329	CHAT	Q05655	PRKCD	S377	R383C	383	Missense	distal	6	no	8.071	7.995	EPSD	COSMIC	7.604	Down-regulation
AGC_PKC_PKCd_PRKCD_ST	P28329	CHAT	Q05655	PRKCD	S377	D376G	376	Missense	proximal	-1	no	8.071	8.055	EPSD	COSMIC	7.604	Down-regulation
AGC_PKC_PKCd_PRKCD_ST	P28329	CHAT	Q05655	PRKCD	S377	R383H	383	Missense	distal	6	no	8.071	8.021	EPSD	COSMIC	7.604	Down-regulation
AGC_PKC_PKCd_PRKCD_ST	P28329	CHAT	Q05655	PRKCD	S464	R466Q	466	Missense	proximal	2	no	9.423	2.633	EPSD	COSMIC	7.604	Loss
AGC_PKC_PKCd_PRKCD_ST	P28329	CHAT	Q05655	PRKCD	S464	R466L	466	Missense	proximal	2	no	9.423	2.545	EPSD	COSMIC	7.604	Loss
AGC_PKC_PKCd_PRKCD_ST	P28329	CHAT	Q05655	PRKCD	S473	A479T	479	Missense	distal	6	no	8.924	8.936	EPSD	COSMIC	7.604	Up-regulation
AGC_PKC_PKCd_PRKCD_ST	P28329	CHAT	Q05655	PRKCD	S473	R466Q	466	Missense	distal	-7	no	8.924	8.908	EPSD	COSMIC	7.604	Down-regulation
AGC_PKC_PKCd_PRKCD_ST	P28329	CHAT	Q05655	PRKCD	S473	R466L	466	Missense	distal	-7	no	8.924	8.901	EPSD	COSMIC	7.604	Down-regulation
AGC_PKC_PKCd_PRKCD_ST	P28329	CHAT	Q05655	PRKCD	S473	P478S	478	Missense	distal	5	no	8.924	8.892	EPSD	COSMIC	7.604	Down-regulation
AGC_PKC_PKCd_PRKCD_ST	P28329	CHAT	Q05655	PRKCD	S473	S475G	475	Missense	proximal	2	no	8.924	8.656	EPSD	COSMIC	7.604	Down-regulation
AGC_PKC_PKCd_PRKCD_ST	P28329	CHAT	Q05655	PRKCD	S558	E555K	555	Missense	distal	-3	no	9.671	14.057	EPSD	COSMIC	7.604	Up-regulation
AGC_PKC_PKCd_PRKCD_ST	P28329	CHAT	Q05655	PRKCD	S558	A557T	557	Missense	proximal	-1	no	9.671	9.687	EPSD	COSMIC;GDSC	7.604	Up-regulation
AGC_PKC_PKCd_PRKCD_ST	P28329	CHAT	Q05655	PRKCD	S558	R560C	560	Missense	proximal	2	no	9.671	2.792	EPSD	COSMIC	7.604	Loss
AGC_PKC_PKCd_PRKCD_ST	P28329	CHAT	Q05655	PRKCD	S558	V551A	551	Missense	distal	-7	no	9.671	9.677	EPSD	COSMIC	7.604	Up-regulation
AGC_PKC_PKCd_PRKCD_ST	P28329	CHAT	Q05655	PRKCD	S594	K588M	588	Missense	distal	-6	no	9.664	10.154	EPSD	COSMIC	7.604	Up-regulation
AGC_PKC_PKCd_PRKCD_ST	P28329	CHAT	Q05655	PRKCD	S594	L599F	599	Missense	distal	5	no	9.664	9.643	EPSD	COSMIC	7.604	Down-regulation
AGC_PKC_PKCd_PRKCD_ST	P28329	CHAT	Q05655	PRKCD	S594	E595K	595	Missense	proximal	1	no	9.664	9.824	EPSD	COSMIC	7.604	Up-regulation
AGC_PKC_PKCd_PRKCD_ST	P13498	CYBA	Q05655	PRKCD	S168	A161T	161	Missense	distal	-7	no	10.563	10.565	EPSD	COSMIC	7.604	Up-regulation
AGC_PKC_PKCd_PRKCD_ST	P04637	TP53	Q05655	PRKCD	S15	E17K	17	Missense	proximal	2	no	5.430	11.185	EPSD	COSMIC	7.604	Gain
AGC_PKC_PKCd_PRKCD_ST	P04637	TP53	Q05655	PRKCD	S20	T18R	18	Missense	proximal	-2	no	1.841	7.804	EPSD	COSMIC	7.604	Gain
AGC_PKC_PKCd_PRKCD_ST	P04637	TP53	Q05655	PRKCD	S33	L35R	35	Missense	proximal	2	no	1.972	8.849	EPSD	COSMIC	7.604	Gain
AGC_PKC_PKCd_PRKCD_ST	P04637	TP53	Q05655	PRKCD	S37	L35R	35	Missense	proximal	-2	no	3.779	9.911	EPSD	COSMIC	7.604	Gain
AGC_PKC_PKCd_PRKCD_ST	P04637	TP53	Q05655	PRKCD	S46	M44R	44	Missense	proximal	-2	no	2.557	8.105	PhosphoSitePlus	COSMIC	7.604	Gain
AGC_PKC_PKCd_PRKCD_ST	P04637	TP53	Q05655	PRKCD	S99	S99F	99	Missense	central	0	yes	8.382	0.000	EPSD	COSMIC	7.604	Loss
AGC_PKC_PKCd_PRKCD_ST	P04637	TP53	Q05655	PRKCD	S99	S96F	96	Missense	distal	-3	no	8.382	8.434	EPSD	COSMIC	7.604	Up-regulation
AGC_PKC_PKCd_PRKCD_ST	P04637	TP53	Q05655	PRKCD	S99	P98S	98	Missense	proximal	-1	no	8.382	8.423	EPSD	COSMIC;CCLE	7.604	Up-regulation
AGC_PKC_PKCd_PRKCD_ST	P04637	TP53	Q05655	PRKCD	S99	T102I	102	Missense	distal	3	no	8.382	8.070	EPSD	COSMIC	7.604	Down-regulation
AGC_PKC_PKCd_PRKCD_ST	P04637	TP53	Q05655	PRKCD	S99	S94P	94	Missense	distal	-5	no	8.382	8.374	EPSD	COSMIC	7.604	Down-regulation
AGC_PKC_PKCd_PRKCD_ST	P04637	TP53	Q05655	PRKCD	S99	K101R	101	Missense	proximal	2	no	8.382	9.560	EPSD	COSMIC	7.604	Up-regulation
AGC_PKC_PKCd_PRKCD_ST	P04637	TP53	Q05655	PRKCD	S99	S94T	94	Missense	distal	-5	no	8.382	8.357	EPSD	COSMIC	7.604	Down-regulation
AGC_PKC_PKCd_PRKCD_ST	P04637	TP53	Q05655	PRKCD	S99	P98L	98	Missense	proximal	-1	no	8.382	8.307	EPSD	COSMIC;GDSC;CCLE	7.604	Down-regulation
AGC_PKC_PKCd_PRKCD_ST	P04637	TP53	Q05655	PRKCD	S99	S95F	95	Missense	distal	-4	no	8.382	8.513	EPSD	COSMIC;CCLE	7.604	Up-regulation
AGC_PKC_PKCd_PRKCD_ST	P04637	TP53	Q05655	PRKCD	S99	S96C	96	Missense	distal	-3	no	8.382	7.638	EPSD	COSMIC	7.604	Down-regulation
AGC_PKC_PKCd_PRKCD_ST	P04637	TP53	Q05655	PRKCD	S99	S106I	106	Missense	distal	7	no	8.382	8.314	EPSD	COSMIC	7.604	Down-regulation
AGC_PKC_PKCd_PRKCD_ST	P04637	TP53	Q05655	PRKCD	S99	P98F	98	Missense	proximal	-1	no	8.382	8.316	EPSD	COSMIC	7.604	Down-regulation
AGC_PKC_PKCd_PRKCD_ST	P04637	TP53	Q05655	PRKCD	S99	T102P	102	Missense	distal	3	no	8.382	8.518	EPSD	COSMIC	7.604	Up-regulation
AGC_PKC_PKCd_PRKCD_ST	P04637	TP53	Q05655	PRKCD	S99	S94L	94	Missense	distal	-5	no	8.382	8.227	EPSD	COSMIC	7.604	Down-regulation
AGC_PKC_PKCd_PRKCD_ST	P04637	TP53	Q05655	PRKCD	S99	S96P	96	Missense	distal	-3	no	8.382	8.714	EPSD	COSMIC	7.604	Up-regulation
AGC_PKC_PKCd_PRKCD_ST	P04637	TP53	Q05655	PRKCD	S99	P98T	98	Missense	proximal	-1	no	8.382	8.361	EPSD	COSMIC	7.604	Down-regulation
AGC_PKC_PKCd_PRKCD_ST	P04637	TP53	Q05655	PRKCD	S99	S96Y	96	Missense	distal	-3	no	8.382	7.079	EPSD	COSMIC	7.604	Loss
AGC_PKC_PKCd_PRKCD_ST	P04637	TP53	Q05655	PRKCD	S99	S99P	99	Missense	central	0	yes	8.382	0.000	EPSD	COSMIC	7.604	Loss
AGC_PKC_PKCd_PRKCD_ST	P04637	TP53	Q05655	PRKCD	S99	V97I	97	Missense	proximal	-2	no	8.382	7.100	EPSD	COSMIC	7.604	Loss
AGC_PKC_PKCd_PRKCD_ST	P04637	TP53	Q05655	PRKCD	S99	Q104H	104	Missense	distal	5	no	8.382	8.364	EPSD	COSMIC	7.604	Down-regulation
AGC_PKC_PKCd_PRKCD_ST	P04637	TP53	Q05655	PRKCD	S99	L93M	93	Missense	distal	-6	no	8.382	8.377	EPSD	COSMIC	7.604	Down-regulation
AGC_PKC_PKCd_PRKCD_ST	P04637	TP53	Q05655	PRKCD	S99	K101N	101	Missense	proximal	2	no	8.382	3.009	EPSD	COSMIC	7.604	Loss
AGC_PKC_PKCd_PRKCD_ST	P04637	TP53	Q05655	PRKCD	S99	V97A	97	Missense	proximal	-2	no	8.382	9.014	EPSD	COSMIC	7.604	Up-regulation
AGC_PKC_PKCd_PRKCD_ST	P04637	TP53	Q05655	PRKCD	S99	P92A	92	Missense	distal	-7	no	8.382	8.377	EPSD	COSMIC	7.604	Down-regulation
AGC_PKC_PKCd_PRKCD_ST	P04637	TP53	Q05655	PRKCD	S99	Q104L	104	Missense	distal	5	no	8.382	8.298	EPSD	COSMIC	7.604	Down-regulation
AGC_PKC_PKCd_PRKCD_ST	P04637	TP53	Q05655	PRKCD	S99	P92L	92	Missense	distal	-7	no	8.382	8.372	EPSD	COSMIC	7.604	Down-regulation
AGC_PKC_PKCd_PRKCD_ST	P04637	TP53	Q05655	PRKCD	S99	L93P	93	Missense	distal	-6	no	8.382	8.214	EPSD	COSMIC	7.604	Down-regulation
AGC_PKC_PKCd_PRKCD_ST	P04637	TP53	Q05655	PRKCD	S99	L93F	93	Missense	distal	-6	no	8.382	8.342	EPSD	COSMIC	7.604	Down-regulation
AGC_PKC_PKCd_PRKCD_ST	P04637	TP53	Q05655	PRKCD	S99	L93H	93	Missense	distal	-6	no	8.382	8.238	EPSD	COSMIC	7.604	Down-regulation
AGC_PKC_PKCd_PRKCD_ST	P04637	TP53	Q05655	PRKCD	S99	S95Y	95	Missense	distal	-4	no	8.382	8.604	EPSD	COSMIC	7.604	Up-regulation
AGC_PKC_PKCd_PRKCD_ST	P04637	TP53	Q05655	PRKCD	S183	G187V	187	Missense	distal	4	no	7.852	7.828	EPSD	COSMIC	7.604	Down-regulation
AGC_PKC_PKCd_PRKCD_ST	P04637	TP53	Q05655	PRKCD	S183	G187D	187	Missense	distal	4	no	7.852	7.891	EPSD	COSMIC	7.604	Up-regulation
AGC_PKC_PKCd_PRKCD_ST	P04637	TP53	Q05655	PRKCD	S183	G187A	187	Missense	distal	4	no	7.852	7.982	EPSD	COSMIC	7.604	Up-regulation
AGC_PKC_PKCd_PRKCD_ST	P04637	TP53	Q05655	PRKCD	S183	S183C	183	Missense	central	0	yes	7.852	0.000	EPSD	COSMIC	7.604	Loss
AGC_PKC_PKCd_PRKCD_ST	P04637	TP53	Q05655	PRKCD	S183	S183P	183	Missense	central	0	yes	7.852	0.000	EPSD	COSMIC	7.604	Loss
AGC_PKC_PKCd_PRKCD_ST	P04637	TP53	Q05655	PRKCD	S183	S185G	185	Missense	proximal	2	no	7.852	7.584	EPSD	COSMIC	7.604	Loss
AGC_PKC_PKCd_PRKCD_ST	P04637	TP53	Q05655	PRKCD	S183	P190N	190	Missense	distal	7	no	7.852	7.832	EPSD	COSMIC	7.604	Down-regulation
AGC_PKC_PKCd_PRKCD_ST	P04637	TP53	Q05655	PRKCD	S183	D184N	184	Missense	proximal	1	no	7.852	7.845	EPSD	COSMIC	7.604	Down-regulation
AGC_PKC_PKCd_PRKCD_ST	P04637	TP53	Q05655	PRKCD	S183	S185R	185	Missense	proximal	2	no	7.852	13.915	EPSD	COSMIC	7.604	Up-regulation
AGC_PKC_PKCd_PRKCD_ST	P04637	TP53	Q05655	PRKCD	S183	S183L	183	Missense	central	0	yes	7.852	0.000	EPSD	COSMIC	7.604	Loss
AGC_PKC_PKCd_PRKCD_ST	P04637	TP53	Q05655	PRKCD	S183	R181L	181	Missense	proximal	-2	no	7.852	1.719	EPSD	COSMIC	7.604	Loss
AGC_PKC_PKCd_PRKCD_ST	P04637	TP53	Q05655	PRKCD	S183	H178P	178	Missense	distal	-5	no	7.852	7.905	EPSD	COSMIC	7.604	Up-regulation
AGC_PKC_PKCd_PRKCD_ST	P04637	TP53	Q05655	PRKCD	S183	D186N	186	Missense	distal	3	no	7.852	7.827	EPSD	COSMIC	7.604	Down-regulation
AGC_PKC_PKCd_PRKCD_ST	P04637	TP53	Q05655	PRKCD	S183	A189S	189	Missense	distal	6	no	7.852	7.870	EPSD	COSMIC	7.604	Up-regulation
AGC_PKC_PKCd_PRKCD_ST	P04637	TP53	Q05655	PRKCD	S183	H178L	178	Missense	distal	-5	no	7.852	7.758	EPSD	COSMIC	7.604	Down-regulation
AGC_PKC_PKCd_PRKCD_ST	P04637	TP53	Q05655	PRKCD	S183	D184Y	184	Missense	proximal	1	no	7.852	7.812	EPSD	COSMIC	7.604	Down-regulation
AGC_PKC_PKCd_PRKCD_ST	P04637	TP53	Q05655	PRKCD	S183	L188V	188	Missense	distal	5	no	7.852	7.785	EPSD	COSMIC	7.604	Down-regulation
AGC_PKC_PKCd_PRKCD_ST	P04637	TP53	Q05655	PRKCD	S183	A189V	189	Missense	distal	6	no	7.852	7.835	EPSD	COSMIC	7.604	Down-regulation
AGC_PKC_PKCd_PRKCD_ST	P04637	TP53	Q05655	PRKCD	S183	H178Y	178	Missense	distal	-5	no	7.852	7.711	EPSD	COSMIC	7.604	Down-regulation
AGC_PKC_PKCd_PRKCD_ST	P04637	TP53	Q05655	PRKCD	S183	D186E	186	Missense	distal	3	no	7.852	7.781	EPSD	COSMIC	7.604	Down-regulation
AGC_PKC_PKCd_PRKCD_ST	P04637	TP53	Q05655	PRKCD	S183	C182Y	182	Missense	proximal	-1	no	7.852	7.843	EPSD	COSMIC	7.604	Down-regulation
AGC_PKC_PKCd_PRKCD_ST	P04637	TP53	Q05655	PRKCD	S183	D186H	186	Missense	distal	3	no	7.852	8.067	EPSD	COSMIC	7.604	Up-regulation
AGC_PKC_PKCd_PRKCD_ST	P04637	TP53	Q05655	PRKCD	S183	L188Q	188	Missense	distal	5	no	7.852	7.937	EPSD	COSMIC	7.604	Up-regulation
AGC_PKC_PKCd_PRKCD_ST	P04637	TP53	Q05655	PRKCD	S183	H178N	178	Missense	distal	-5	no	7.852	7.784	EPSD	COSMIC	7.604	Down-regulation
AGC_PKC_PKCd_PRKCD_ST	P04637	TP53	Q05655	PRKCD	S183	G187R	187	Missense	distal	4	no	7.852	8.519	EPSD	COSMIC;GDSC	7.604	Up-regulation
AGC_PKC_PKCd_PRKCD_ST	P04637	TP53	Q05655	PRKCD	S183	C182S	182	Missense	proximal	-1	no	7.852	7.989	EPSD	COSMIC	7.604	Up-regulation
AGC_PKC_PKCd_PRKCD_ST	P04637	TP53	Q05655	PRKCD	S183	P190F	190	Missense	distal	7	no	7.852	7.833	EPSD	COSMIC	7.604	Down-regulation
AGC_PKC_PKCd_PRKCD_ST	P04637	TP53	Q05655	PRKCD	S183	G187C	187	Missense	distal	4	no	7.852	7.723	EPSD	COSMIC	7.604	Down-regulation
AGC_PKC_PKCd_PRKCD_ST	P04637	TP53	Q05655	PRKCD	S183	S185T	185	Missense	proximal	2	no	7.852	7.660	EPSD	COSMIC	7.604	Down-regulation
AGC_PKC_PKCd_PRKCD_ST	P04637	TP53	Q05655	PRKCD	S183	P190H	190	Missense	distal	7	no	7.852	7.858	EPSD	COSMIC	7.604	Up-regulation
AGC_PKC_PKCd_PRKCD_ST	P04637	TP53	Q05655	PRKCD	S183	S185N	185	Missense	proximal	2	no	7.852	7.364	EPSD	COSMIC	7.604	Loss
AGC_PKC_PKCd_PRKCD_ST	P04637	TP53	Q05655	PRKCD	S183	D186G	186	Missense	distal	3	no	7.852	7.819	EPSD	COSMIC	7.604	Down-regulation
AGC_PKC_PKCd_PRKCD_ST	P04637	TP53	Q05655	PRKCD	S183	D186V	186	Missense	distal	3	no	7.852	7.800	EPSD	COSMIC	7.604	Down-regulation
AGC_PKC_PKCd_PRKCD_ST	P04637	TP53	Q05655	PRKCD	S183	P177I	177	Missense	distal	-6	no	7.852	8.044	EPSD	COSMIC	7.604	Up-regulation
AGC_PKC_PKCd_PRKCD_ST	P04637	TP53	Q05655	PRKCD	S183	P190A	190	Missense	distal	7	no	7.852	7.855	EPSD	COSMIC	7.604	Up-regulation
AGC_PKC_PKCd_PRKCD_ST	P04637	TP53	Q05655	PRKCD	S183	S185C	185	Missense	proximal	2	no	7.852	7.036	EPSD	COSMIC	7.604	Loss
AGC_PKC_PKCd_PRKCD_ST	P04637	TP53	Q05655	PRKCD	S183	S185I	185	Missense	proximal	2	no	7.852	6.920	EPSD	COSMIC	7.604	Loss
AGC_PKC_PKCd_PRKCD_ST	P04637	TP53	Q05655	PRKCD	S183	A189P	189	Missense	distal	6	no	7.852	7.864	EPSD	COSMIC	7.604	Up-regulation
AGC_PKC_PKCd_PRKCD_ST	P04637	TP53	Q05655	PRKCD	S183	E180Q	180	Missense	distal	-3	no	7.852	8.115	EPSD	COSMIC	7.604	Up-regulation
AGC_PKC_PKCd_PRKCD_ST	P04637	TP53	Q05655	PRKCD	S183	R181S	181	Missense	proximal	-2	no	7.852	3.004	EPSD	COSMIC	7.604	Loss
AGC_PKC_PKCd_PRKCD_ST	P04637	TP53	Q05655	PRKCD	S183	C182R	182	Missense	proximal	-1	no	7.852	8.063	EPSD	COSMIC	7.604	Up-regulation
AGC_PKC_PKCd_PRKCD_ST	P04637	TP53	Q05655	PRKCD	S183	E180G	180	Missense	distal	-3	no	7.852	8.064	EPSD	COSMIC	7.604	Up-regulation
AGC_PKC_PKCd_PRKCD_ST	P04637	TP53	Q05655	PRKCD	S183	L188M	188	Missense	distal	5	no	7.852	7.783	EPSD	COSMIC	7.604	Down-regulation
AGC_PKC_PKCd_PRKCD_ST	P04637	TP53	Q05655	PRKCD	S183	P177F	177	Missense	distal	-6	no	7.852	7.981	EPSD	COSMIC	7.604	Up-regulation
AGC_PKC_PKCd_PRKCD_ST	P04637	TP53	Q05655	PRKCD	S183	D184E	184	Missense	proximal	1	no	7.852	7.880	EPSD	COSMIC	7.604	Up-regulation
AGC_PKC_PKCd_PRKCD_ST	P04637	TP53	Q05655	PRKCD	S183	A189G	189	Missense	distal	6	no	7.852	7.844	EPSD	COSMIC	7.604	Down-regulation
AGC_PKC_PKCd_PRKCD_ST	P04637	TP53	Q05655	PRKCD	S183	R181G	181	Missense	proximal	-2	no	7.852	2.088	EPSD	COSMIC	7.604	Loss
AGC_PKC_PKCd_PRKCD_ST	P04637	TP53	Q05655	PRKCD	S183	D186X	186	Missense	distal	3	no	7.852	7.821	EPSD	COSMIC	7.604	Down-regulation
AGC_PKC_PKCd_PRKCD_ST	P04637	TP53	Q05655	PRKCD	S183	R181Y	181	Missense	proximal	-2	no	7.852	1.011	EPSD	COSMIC	7.604	Loss
AGC_PKC_PKCd_PRKCD_ST	P04637	TP53	Q05655	PRKCD	S183	D184G	184	Missense	proximal	1	no	7.852	7.822	EPSD	COSMIC	7.604	Down-regulation
AGC_PKC_PKCd_PRKCD_ST	P04637	TP53	Q05655	PRKCD	T211	R209Q	209	Missense	proximal	-2	no	12.679	7.244	EPSD	COSMIC	7.604	Loss
AGC_PKC_PKCd_PRKCD_ST	P04637	TP53	Q05655	PRKCD	T211	R209W	209	Missense	proximal	-2	no	12.679	6.425	EPSD	COSMIC	7.604	Loss
AGC_PKC_PKCd_PRKCD_ST	P04637	TP53	Q05655	PRKCD	T211	R209P	209	Missense	proximal	-2	no	12.679	8.216	EPSD	COSMIC	7.604	Down-regulation
AGC_PKC_PKCd_PRKCD_ST	P04637	TP53	Q05655	PRKCD	T211	R209L	209	Missense	proximal	-2	no	12.679	6.546	EPSD	COSMIC	7.604	Loss
AGC_PKC_PKCd_PRKCD_ST	P04637	TP53	Q05655	PRKCD	T211	R209G	209	Missense	proximal	-2	no	12.679	6.915	EPSD	COSMIC	7.604	Loss
AGC_PKC_PKCd_PRKCD_ST	P04637	TP53	Q05655	PRKCD	T211	R209C	209	Missense	proximal	-2	no	12.679	6.684	EPSD	COSMIC	7.604	Loss
AGC_PKC_PKCd_PRKCD_ST	P04637	TP53	Q05655	PRKCD	T211	E204K	204	Missense	distal	-7	no	12.679	12.701	EPSD	COSMIC	7.604	Up-regulation
AGC_PKC_PKCd_PRKCD_ST	P04637	TP53	Q05655	PRKCD	T211	V216A	216	Missense	distal	5	no	12.679	12.800	EPSD	COSMIC	7.604	Up-regulation
AGC_PKC_PKCd_PRKCD_ST	P04637	TP53	Q05655	PRKCD	T211	V217A	217	Missense	distal	6	no	12.679	12.696	EPSD	COSMIC	7.604	Up-regulation
AGC_PKC_PKCd_PRKCD_ST	P04637	TP53	Q05655	PRKCD	T211	E204G	204	Missense	distal	-7	no	12.679	12.677	EPSD	COSMIC	7.604	Down-regulation
AGC_PKC_PKCd_PRKCD_ST	P04637	TP53	Q05655	PRKCD	T211	V218M	218	Missense	distal	7	no	12.679	12.685	EPSD	COSMIC	7.604	Up-regulation
AGC_PKC_PKCd_PRKCD_ST	P04637	TP53	Q05655	PRKCD	T211	D208E	208	Missense	distal	-3	no	12.679	12.298	EPSD	COSMIC	7.604	Down-regulation
AGC_PKC_PKCd_PRKCD_ST	P04637	TP53	Q05655	PRKCD	T211	F212L	212	Missense	proximal	1	no	12.679	12.673	EPSD	COSMIC	7.604	Down-regulation
AGC_PKC_PKCd_PRKCD_ST	P04637	TP53	Q05655	PRKCD	T211	H214Q	214	Missense	distal	3	no	12.679	12.489	EPSD	COSMIC	7.604	Down-regulation
AGC_PKC_PKCd_PRKCD_ST	P04637	TP53	Q05655	PRKCD	T211	R213W	213	Missense	proximal	2	no	12.679	6.006	EPSD	COSMIC	7.604	Loss
AGC_PKC_PKCd_PRKCD_ST	P04637	TP53	Q05655	PRKCD	T211	N210D	210	Missense	proximal	-1	no	12.679	12.705	EPSD	COSMIC	7.604	Up-regulation
AGC_PKC_PKCd_PRKCD_ST	P04637	TP53	Q05655	PRKCD	T211	V218A	218	Missense	distal	7	no	12.679	12.717	EPSD	COSMIC	7.604	Up-regulation
AGC_PKC_PKCd_PRKCD_ST	P04637	TP53	Q05655	PRKCD	T211	S215C	215	Missense	distal	4	no	12.679	12.352	EPSD	COSMIC;GDSC;CCLE	7.604	Down-regulation
AGC_PKC_PKCd_PRKCD_ST	P04637	TP53	Q05655	PRKCD	T211	V218L	218	Missense	distal	7	no	12.679	12.684	EPSD	COSMIC;GDSC;CCLE	7.604	Up-regulation
AGC_PKC_PKCd_PRKCD_ST	P04637	TP53	Q05655	PRKCD	T211	E204V	204	Missense	distal	-7	no	12.679	12.675	EPSD	COSMIC	7.604	Down-regulation
AGC_PKC_PKCd_PRKCD_ST	P04637	TP53	Q05655	PRKCD	T211	T211N	211	Missense	central	0	yes	12.679	0.000	EPSD	COSMIC	7.604	Loss
AGC_PKC_PKCd_PRKCD_ST	P04637	TP53	Q05655	PRKCD	T211	N210S	210	Missense	proximal	-1	no	12.679	12.792	EPSD	COSMIC	7.604	Up-regulation
AGC_PKC_PKCd_PRKCD_ST	P04637	TP53	Q05655	PRKCD	T211	D207G	207	Missense	distal	-4	no	12.679	12.702	EPSD	COSMIC	7.604	Up-regulation
AGC_PKC_PKCd_PRKCD_ST	P04637	TP53	Q05655	PRKCD	T211	F212I	212	Missense	proximal	1	no	12.679	12.624	EPSD	COSMIC	7.604	Down-regulation
AGC_PKC_PKCd_PRKCD_ST	P04637	TP53	Q05655	PRKCD	T211	D207A	207	Missense	distal	-4	no	12.679	12.632	EPSD	COSMIC	7.604	Down-regulation
AGC_PKC_PKCd_PRKCD_ST	P04637	TP53	Q05655	PRKCD	T211	N210H	210	Missense	proximal	-1	no	12.679	12.721	EPSD	COSMIC	7.604	Up-regulation
AGC_PKC_PKCd_PRKCD_ST	P04637	TP53	Q05655	PRKCD	T211	V217E	217	Missense	distal	6	no	12.679	12.694	EPSD	COSMIC	7.604	Up-regulation
AGC_PKC_PKCd_PRKCD_ST	P04637	TP53	Q05655	PRKCD	T211	R209T	209	Missense	proximal	-2	no	12.679	6.716	EPSD	COSMIC	7.604	Loss
AGC_PKC_PKCd_PRKCD_ST	P04637	TP53	Q05655	PRKCD	T211	D207Y	207	Missense	distal	-4	no	12.679	12.771	EPSD	COSMIC	7.604	Up-regulation
AGC_PKC_PKCd_PRKCD_ST	P04637	TP53	Q05655	PRKCD	T211	D208Y	208	Missense	distal	-3	no	12.679	11.840	EPSD	COSMIC	7.604	Down-regulation
AGC_PKC_PKCd_PRKCD_ST	P04637	TP53	Q05655	PRKCD	T211	V217L	217	Missense	distal	6	no	12.679	12.684	EPSD	COSMIC	7.604	Up-regulation
AGC_PKC_PKCd_PRKCD_ST	P04637	TP53	Q05655	PRKCD	T211	L206F	206	Missense	distal	-5	no	12.679	12.725	EPSD	COSMIC	7.604	Up-regulation
AGC_PKC_PKCd_PRKCD_ST	P04637	TP53	Q05655	PRKCD	T211	E204A	204	Missense	distal	-7	no	12.679	12.681	EPSD	COSMIC	7.604	Up-regulation
AGC_PKC_PKCd_PRKCD_ST	P04637	TP53	Q05655	PRKCD	T211	D208H	208	Missense	distal	-3	no	12.679	13.464	EPSD	COSMIC	7.604	Up-regulation
AGC_PKC_PKCd_PRKCD_ST	P04637	TP53	Q05655	PRKCD	T211	V217M	217	Missense	distal	6	no	12.679	12.680	EPSD	COSMIC	7.604	Up-regulation
AGC_PKC_PKCd_PRKCD_ST	P04637	TP53	Q05655	PRKCD	T211	D207E	207	Missense	distal	-4	no	12.679	12.683	EPSD	COSMIC	7.604	Up-regulation
AGC_PKC_PKCd_PRKCD_ST	P04637	TP53	Q05655	PRKCD	T211	N210T	210	Missense	proximal	-1	no	12.679	12.730	EPSD	COSMIC	7.604	Up-regulation
AGC_PKC_PKCd_PRKCD_ST	P04637	TP53	Q05655	PRKCD	T211	N210K	210	Missense	proximal	-1	no	12.679	12.860	EPSD	COSMIC	7.604	Up-regulation
AGC_PKC_PKCd_PRKCD_ST	P04637	TP53	Q05655	PRKCD	T211	F212S	212	Missense	proximal	1	no	12.679	12.728	EPSD	COSMIC	7.604	Up-regulation
AGC_PKC_PKCd_PRKCD_ST	P04637	TP53	Q05655	PRKCD	T211	H214P	214	Missense	distal	3	no	12.679	12.704	EPSD	COSMIC	7.604	Up-regulation
AGC_PKC_PKCd_PRKCD_ST	P04637	TP53	Q05655	PRKCD	T211	D208I	208	Missense	distal	-3	no	12.679	12.077	EPSD	COSMIC	7.604	Down-regulation
AGC_PKC_PKCd_PRKCD_ST	P04637	TP53	Q05655	PRKCD	T211	F212Y	212	Missense	proximal	1	no	12.679	12.611	EPSD	COSMIC	7.604	Down-regulation
AGC_PKC_PKCd_PRKCD_ST	P04637	TP53	Q05655	PRKCD	T211	H214A	214	Missense	distal	3	no	12.679	12.644	EPSD	COSMIC	7.604	Down-regulation
AGC_PKC_PKCd_PRKCD_ST	P04637	TP53	Q05655	PRKCD	S215	R209Q	209	Missense	distal	-6	no	7.714	8.017	EPSD	COSMIC	7.604	Up-regulation
AGC_PKC_PKCd_PRKCD_ST	P04637	TP53	Q05655	PRKCD	S215	R209W	209	Missense	distal	-6	no	7.714	8.307	EPSD	COSMIC	7.604	Up-regulation
AGC_PKC_PKCd_PRKCD_ST	P04637	TP53	Q05655	PRKCD	S215	R209P	209	Missense	distal	-6	no	7.714	7.992	EPSD	COSMIC	7.604	Up-regulation
AGC_PKC_PKCd_PRKCD_ST	P04637	TP53	Q05655	PRKCD	S215	R209L	209	Missense	distal	-6	no	7.714	8.161	EPSD	COSMIC	7.604	Up-regulation
AGC_PKC_PKCd_PRKCD_ST	P04637	TP53	Q05655	PRKCD	S215	R209G	209	Missense	distal	-6	no	7.714	8.107	EPSD	COSMIC	7.604	Up-regulation
AGC_PKC_PKCd_PRKCD_ST	P04637	TP53	Q05655	PRKCD	S215	R209C	209	Missense	distal	-6	no	7.714	8.185	EPSD	COSMIC	7.604	Up-regulation
AGC_PKC_PKCd_PRKCD_ST	P04637	TP53	Q05655	PRKCD	S215	V216A	216	Missense	proximal	1	no	7.714	7.731	EPSD	COSMIC	7.604	Up-regulation
AGC_PKC_PKCd_PRKCD_ST	P04637	TP53	Q05655	PRKCD	S215	V217A	217	Missense	proximal	2	no	7.714	8.862	EPSD	COSMIC	7.604	Up-regulation
AGC_PKC_PKCd_PRKCD_ST	P04637	TP53	Q05655	PRKCD	S215	P222S	222	Missense	distal	7	no	7.714	7.743	EPSD	COSMIC	7.604	Up-regulation
AGC_PKC_PKCd_PRKCD_ST	P04637	TP53	Q05655	PRKCD	S215	P219L	219	Missense	distal	4	no	7.714	7.510	EPSD	COSMIC	7.604	Loss
AGC_PKC_PKCd_PRKCD_ST	P04637	TP53	Q05655	PRKCD	S215	V218M	218	Missense	distal	3	no	7.714	7.740	EPSD	COSMIC	7.604	Up-regulation
AGC_PKC_PKCd_PRKCD_ST	P04637	TP53	Q05655	PRKCD	S215	F212L	212	Missense	distal	-3	no	7.714	7.051	EPSD	COSMIC	7.604	Loss
AGC_PKC_PKCd_PRKCD_ST	P04637	TP53	Q05655	PRKCD	S215	H214Q	214	Missense	proximal	-1	no	7.714	7.723	EPSD	COSMIC	7.604	Up-regulation
AGC_PKC_PKCd_PRKCD_ST	P04637	TP53	Q05655	PRKCD	S215	P219H	219	Missense	distal	4	no	7.714	7.603	EPSD	COSMIC	7.604	Loss
AGC_PKC_PKCd_PRKCD_ST	P04637	TP53	Q05655	PRKCD	S215	R213W	213	Missense	proximal	-2	no	7.714	1.461	EPSD	COSMIC	7.604	Loss
AGC_PKC_PKCd_PRKCD_ST	P04637	TP53	Q05655	PRKCD	S215	N210D	210	Missense	distal	-5	no	7.714	7.738	EPSD	COSMIC	7.604	Up-regulation
AGC_PKC_PKCd_PRKCD_ST	P04637	TP53	Q05655	PRKCD	S215	V218A	218	Missense	distal	3	no	7.714	7.947	EPSD	COSMIC	7.604	Up-regulation
AGC_PKC_PKCd_PRKCD_ST	P04637	TP53	Q05655	PRKCD	S215	S215C	215	Missense	central	0	yes	7.714	0.000	EPSD	COSMIC;GDSC;CCLE	7.604	Loss
AGC_PKC_PKCd_PRKCD_ST	P04637	TP53	Q05655	PRKCD	S215	V218L	218	Missense	distal	3	no	7.714	7.726	EPSD	COSMIC;GDSC;CCLE	7.604	Up-regulation
AGC_PKC_PKCd_PRKCD_ST	P04637	TP53	Q05655	PRKCD	S215	T211N	211	Missense	distal	-4	no	7.714	7.817	EPSD	COSMIC	7.604	Up-regulation
AGC_PKC_PKCd_PRKCD_ST	P04637	TP53	Q05655	PRKCD	S215	N210S	210	Missense	distal	-5	no	7.714	7.845	EPSD	COSMIC	7.604	Up-regulation
AGC_PKC_PKCd_PRKCD_ST	P04637	TP53	Q05655	PRKCD	S215	P222T	222	Missense	distal	7	no	7.714	7.736	EPSD	COSMIC	7.604	Up-regulation
AGC_PKC_PKCd_PRKCD_ST	P04637	TP53	Q05655	PRKCD	S215	F212I	212	Missense	distal	-3	no	7.714	6.596	EPSD	COSMIC	7.604	Loss
AGC_PKC_PKCd_PRKCD_ST	P04637	TP53	Q05655	PRKCD	S215	N210H	210	Missense	distal	-5	no	7.714	7.783	EPSD	COSMIC	7.604	Up-regulation
AGC_PKC_PKCd_PRKCD_ST	P04637	TP53	Q05655	PRKCD	S215	E221G	221	Missense	distal	6	no	7.714	7.708	EPSD	COSMIC	7.604	Down-regulation
AGC_PKC_PKCd_PRKCD_ST	P04637	TP53	Q05655	PRKCD	S215	V217E	217	Missense	proximal	2	no	7.714	7.153	EPSD	COSMIC	7.604	Loss
AGC_PKC_PKCd_PRKCD_ST	P04637	TP53	Q05655	PRKCD	S215	R209T	209	Missense	distal	-6	no	7.714	7.956	EPSD	COSMIC	7.604	Up-regulation
AGC_PKC_PKCd_PRKCD_ST	P04637	TP53	Q05655	PRKCD	S215	P222L	222	Missense	distal	7	no	7.714	7.684	EPSD	COSMIC	7.604	Down-regulation
AGC_PKC_PKCd_PRKCD_ST	P04637	TP53	Q05655	PRKCD	S215	P219R	219	Missense	distal	4	no	7.714	8.146	EPSD	COSMIC	7.604	Up-regulation
AGC_PKC_PKCd_PRKCD_ST	P04637	TP53	Q05655	PRKCD	S215	P219S	219	Missense	distal	4	no	7.714	7.676	EPSD	COSMIC	7.604	Down-regulation
AGC_PKC_PKCd_PRKCD_ST	P04637	TP53	Q05655	PRKCD	S215	D208Y	208	Missense	distal	-7	no	7.714	7.707	EPSD	COSMIC	7.604	Down-regulation
AGC_PKC_PKCd_PRKCD_ST	P04637	TP53	Q05655	PRKCD	S215	P222Q	222	Missense	distal	7	no	7.714	7.716	EPSD	COSMIC	7.604	Up-regulation
AGC_PKC_PKCd_PRKCD_ST	P04637	TP53	Q05655	PRKCD	S215	P222A	222	Missense	distal	7	no	7.714	7.717	EPSD	COSMIC	7.604	Up-regulation
AGC_PKC_PKCd_PRKCD_ST	P04637	TP53	Q05655	PRKCD	S215	V217L	217	Missense	proximal	2	no	7.714	7.207	EPSD	COSMIC	7.604	Loss
AGC_PKC_PKCd_PRKCD_ST	P04637	TP53	Q05655	PRKCD	S215	T211S	211	Missense	distal	-4	no	7.714	7.663	EPSD	COSMIC	7.604	Down-regulation
AGC_PKC_PKCd_PRKCD_ST	P04637	TP53	Q05655	PRKCD	S215	D208H	208	Missense	distal	-7	no	7.714	7.717	EPSD	COSMIC	7.604	Up-regulation
AGC_PKC_PKCd_PRKCD_ST	P04637	TP53	Q05655	PRKCD	S215	V217M	217	Missense	proximal	2	no	7.714	7.894	EPSD	COSMIC	7.604	Up-regulation
AGC_PKC_PKCd_PRKCD_ST	P04637	TP53	Q05655	PRKCD	S215	N210T	210	Missense	distal	-5	no	7.714	7.819	EPSD	COSMIC	7.604	Up-regulation
AGC_PKC_PKCd_PRKCD_ST	P04637	TP53	Q05655	PRKCD	S215	N210K	210	Missense	distal	-5	no	7.714	8.093	EPSD	COSMIC	7.604	Up-regulation
AGC_PKC_PKCd_PRKCD_ST	P04637	TP53	Q05655	PRKCD	S215	F212S	212	Missense	distal	-3	no	7.714	7.663	EPSD	COSMIC	7.604	Down-regulation
AGC_PKC_PKCd_PRKCD_ST	P04637	TP53	Q05655	PRKCD	S215	H214P	214	Missense	proximal	-1	no	7.714	7.744	EPSD	COSMIC	7.604	Up-regulation
AGC_PKC_PKCd_PRKCD_ST	P04637	TP53	Q05655	PRKCD	S215	D208I	208	Missense	distal	-7	no	7.714	7.708	EPSD	COSMIC	7.604	Down-regulation
AGC_PKC_PKCd_PRKCD_ST	P04637	TP53	Q05655	PRKCD	S215	P219C	219	Missense	distal	4	no	7.714	7.350	EPSD	COSMIC	7.604	Loss
AGC_PKC_PKCd_PRKCD_ST	P04637	TP53	Q05655	PRKCD	S215	F212Y	212	Missense	distal	-3	no	7.714	6.359	EPSD	COSMIC	7.604	Loss
AGC_PKC_PKCd_PRKCD_ST	P04637	TP53	Q05655	PRKCD	S215	Y220L	220	Missense	distal	5	no	7.714	7.863	EPSD	COSMIC	7.604	Up-regulation
AGC_PKC_PKCd_PRKCD_ST	P04637	TP53	Q05655	PRKCD	S215	Y220X	220	Missense	distal	5	no	7.714	7.820	EPSD	COSMIC	7.604	Up-regulation
AGC_PKC_PKCd_PRKCD_ST	P04637	TP53	Q05655	PRKCD	S215	H214A	214	Missense	proximal	-1	no	7.714	7.707	EPSD	COSMIC	7.604	Down-regulation
AGC_PKC_PKCd_PRKCD_ST	P04637	TP53	Q05655	PRKCD	S269	A276S	276	Missense	distal	7	no	8.933	8.959	EPSD	COSMIC	7.604	Up-regulation
AGC_PKC_PKCd_PRKCD_ST	P04637	TP53	Q05655	PRKCD	S269	G262H	262	Missense	distal	-7	no	8.933	8.938	EPSD	COSMIC	7.604	Up-regulation
AGC_PKC_PKCd_PRKCD_ST	P04637	TP53	Q05655	PRKCD	S269	N263H	263	Missense	distal	-6	no	8.933	8.834	EPSD	COSMIC	7.604	Down-regulation
AGC_PKC_PKCd_PRKCD_ST	P04637	TP53	Q05655	PRKCD	S269	G266A	266	Missense	distal	-3	no	8.933	9.803	EPSD	COSMIC	7.604	Up-regulation
AGC_PKC_PKCd_PRKCD_ST	P04637	TP53	Q05655	PRKCD	S269	S269N	269	Missense	central	0	yes	8.933	0.000	EPSD	COSMIC	7.604	Loss
AGC_PKC_PKCd_PRKCD_ST	P04637	TP53	Q05655	PRKCD	S269	V274I	274	Missense	distal	5	no	8.933	8.857	EPSD	COSMIC	7.604	Down-regulation
AGC_PKC_PKCd_PRKCD_ST	P04637	TP53	Q05655	PRKCD	S269	L265M	265	Missense	distal	-4	no	8.933	8.934	EPSD	COSMIC	7.604	Up-regulation
AGC_PKC_PKCd_PRKCD_ST	P04637	TP53	Q05655	PRKCD	S269	F270Y	270	Missense	proximal	1	no	8.933	8.866	EPSD	COSMIC	7.604	Down-regulation
AGC_PKC_PKCd_PRKCD_ST	P04637	TP53	Q05655	PRKCD	S269	L264V	264	Missense	distal	-5	no	8.933	8.934	EPSD	COSMIC	7.604	Up-regulation
AGC_PKC_PKCd_PRKCD_ST	P04637	TP53	Q05655	PRKCD	S269	S269G	269	Missense	central	0	yes	8.933	0.000	EPSD	COSMIC	7.604	Loss
AGC_PKC_PKCd_PRKCD_ST	P04637	TP53	Q05655	PRKCD	S269	R273Q	273	Missense	distal	4	no	8.933	8.345	EPSD	COSMIC	7.604	Down-regulation
AGC_PKC_PKCd_PRKCD_ST	P04637	TP53	Q05655	PRKCD	S269	N268H	268	Missense	proximal	-1	no	8.933	8.975	EPSD	COSMIC	7.604	Up-regulation
AGC_PKC_PKCd_PRKCD_ST	P04637	TP53	Q05655	PRKCD	S269	G262D	262	Missense	distal	-7	no	8.933	8.935	EPSD	COSMIC;GDSC;CCLE	7.604	Up-regulation
AGC_PKC_PKCd_PRKCD_ST	P04637	TP53	Q05655	PRKCD	S269	N263I	263	Missense	distal	-6	no	8.933	9.002	EPSD	COSMIC	7.604	Up-regulation
AGC_PKC_PKCd_PRKCD_ST	P04637	TP53	Q05655	PRKCD	S269	L264P	264	Missense	distal	-5	no	8.933	9.080	EPSD	COSMIC	7.604	Up-regulation
AGC_PKC_PKCd_PRKCD_ST	P04637	TP53	Q05655	PRKCD	S269	E271P	271	Missense	proximal	2	no	8.933	10.047	EPSD	COSMIC	7.604	Up-regulation
AGC_PKC_PKCd_PRKCD_ST	P04637	TP53	Q05655	PRKCD	S269	L264R	264	Missense	distal	-5	no	8.933	9.363	EPSD	COSMIC;GDSC;CCLE	7.604	Up-regulation
AGC_PKC_PKCd_PRKCD_ST	P04637	TP53	Q05655	PRKCD	S269	R273Y	273	Missense	distal	4	no	8.933	8.136	EPSD	COSMIC;CCLE	7.604	Down-regulation
AGC_PKC_PKCd_PRKCD_ST	P04637	TP53	Q05655	PRKCD	S269	N263D	263	Missense	distal	-6	no	8.933	8.886	EPSD	COSMIC	7.604	Down-regulation
AGC_PKC_PKCd_PRKCD_ST	P04637	TP53	Q05655	PRKCD	S269	A276T	276	Missense	distal	7	no	8.933	8.951	EPSD	COSMIC	7.604	Up-regulation
AGC_PKC_PKCd_PRKCD_ST	P04637	TP53	Q05655	PRKCD	S269	S269C	269	Missense	central	0	yes	8.933	0.000	EPSD	COSMIC	7.604	Loss
AGC_PKC_PKCd_PRKCD_ST	P04637	TP53	Q05655	PRKCD	S269	L264I	264	Missense	distal	-5	no	8.933	8.896	EPSD	COSMIC	7.604	Down-regulation
AGC_PKC_PKCd_PRKCD_ST	P04637	TP53	Q05655	PRKCD	S269	N268K	268	Missense	proximal	-1	no	8.933	9.114	EPSD	COSMIC	7.604	Up-regulation
AGC_PKC_PKCd_PRKCD_ST	P04637	TP53	Q05655	PRKCD	S269	A276F	276	Missense	distal	7	no	8.933	8.911	EPSD	COSMIC	7.604	Down-regulation
AGC_PKC_PKCd_PRKCD_ST	P04637	TP53	Q05655	PRKCD	S269	G266T	266	Missense	distal	-3	no	8.933	9.049	EPSD	COSMIC	7.604	Up-regulation
AGC_PKC_PKCd_PRKCD_ST	P04637	TP53	Q05655	PRKCD	S269	G266K	266	Missense	distal	-3	no	8.933	13.106	EPSD	COSMIC	7.604	Up-regulation
AGC_PKC_PKCd_PRKCD_ST	P04637	TP53	Q05655	PRKCD	S269	E271G	271	Missense	proximal	2	no	8.933	9.533	EPSD	COSMIC	7.604	Up-regulation
AGC_PKC_PKCd_PRKCD_ST	P04637	TP53	Q05655	PRKCD	S269	L264Q	264	Missense	distal	-5	no	8.933	9.012	EPSD	COSMIC	7.604	Up-regulation
AGC_PKC_PKCd_PRKCD_ST	P04637	TP53	Q05655	PRKCD	S269	S269I	269	Missense	central	0	yes	8.933	0.000	EPSD	COSMIC	7.604	Loss
AGC_PKC_PKCd_PRKCD_ST	P04637	TP53	Q05655	PRKCD	S269	S269R	269	Missense	central	0	yes	8.933	0.000	EPSD	COSMIC	7.604	Loss
AGC_PKC_PKCd_PRKCD_ST	P04637	TP53	Q05655	PRKCD	S269	G262R	262	Missense	distal	-7	no	8.933	8.955	EPSD	COSMIC	7.604	Up-regulation
AGC_PKC_PKCd_PRKCD_ST	P04637	TP53	Q05655	PRKCD	S269	N263K	263	Missense	distal	-6	no	8.933	8.483	EPSD	COSMIC	7.604	Down-regulation
AGC_PKC_PKCd_PRKCD_ST	P04637	TP53	Q05655	PRKCD	S269	V272K	272	Missense	distal	3	no	8.933	10.095	EPSD	COSMIC	7.604	Up-regulation
AGC_PKC_PKCd_PRKCD_ST	P04637	TP53	Q05655	PRKCD	S269	N268F	268	Missense	proximal	-1	no	8.933	8.939	EPSD	COSMIC	7.604	Up-regulation
AGC_PKC_PKCd_PRKCD_ST	P04637	TP53	Q05655	PRKCD	S269	L265Q	265	Missense	distal	-4	no	8.933	8.855	EPSD	COSMIC	7.604	Down-regulation
AGC_PKC_PKCd_PRKCD_ST	P04637	TP53	Q05655	PRKCD	S269	N268S	268	Missense	proximal	-1	no	8.933	9.046	EPSD	COSMIC	7.604	Up-regulation
AGC_PKC_PKCd_PRKCD_ST	P04637	TP53	Q05655	PRKCD	S269	G262S	262	Missense	distal	-7	no	8.933	8.943	EPSD	COSMIC;GDSC	7.604	Up-regulation
AGC_PKC_PKCd_PRKCD_ST	P04637	TP53	Q05655	PRKCD	S269	G266S	266	Missense	distal	-3	no	8.933	9.566	EPSD	COSMIC	7.604	Up-regulation
AGC_PKC_PKCd_PRKCD_ST	P04637	TP53	Q05655	PRKCD	T284	D281R	281	Missense	distal	-3	no	4.033	9.073	EPSD	COSMIC	7.604	Gain
AGC_PKC_PKCd_PRKCD_ST	P04637	TP53	Q05655	PRKCD	T304	G302R	302	Missense	proximal	-2	no	6.741	12.504	EPSD	COSMIC	7.604	Gain
AGC_PKC_PKCd_PRKCD_ST	P04637	TP53	Q05655	PRKCD	S314	N311K	311	Missense	distal	-3	no	3.711	7.815	EPSD	COSMIC	7.604	Gain
AGC_PKC_PKCd_PRKCD_ST	P04637	TP53	Q05655	PRKCD	S315	Q317R	317	Missense	proximal	2	no	3.857	10.647	EPSD	COSMIC	7.604	Gain
AGC_PKC_PKCd_PRKCD_ST	P04637	TP53	Q05655	PRKCD	S315	Q317K	317	Missense	proximal	2	no	3.857	9.469	EPSD	COSMIC	7.604	Gain
AGC_PKC_PKCd_PRKCD_ST	P04637	TP53	Q05655	PRKCD	S366	S367F	367	Missense	proximal	1	no	9.437	9.388	EPSD	COSMIC	7.604	Down-regulation
AGC_PKC_PKCd_PRKCD_ST	P04637	TP53	Q05655	PRKCD	S366	K370N	370	Missense	distal	4	no	9.437	8.792	EPSD	COSMIC	7.604	Down-regulation
AGC_PKC_PKCd_PRKCD_ST	P04637	TP53	Q05655	PRKCD	S366	G361E	361	Missense	distal	-5	no	9.437	9.467	EPSD	COSMIC	7.604	Up-regulation
AGC_PKC_PKCd_PRKCD_ST	P04637	TP53	Q05655	PRKCD	S366	P359S	359	Missense	distal	-7	no	9.437	9.438	EPSD	COSMIC	7.604	Up-regulation
AGC_PKC_PKCd_PRKCD_ST	P04637	TP53	Q05655	PRKCD	S366	A364D	364	Missense	proximal	-2	no	9.437	8.696	EPSD	COSMIC	7.604	Down-regulation
AGC_PKC_PKCd_PRKCD_ST	P04637	TP53	Q05655	PRKCD	S366	H365Y	365	Missense	proximal	-1	no	9.437	9.362	EPSD	COSMIC	7.604	Down-regulation
AGC_PKC_PKCd_PRKCD_ST	P04637	TP53	Q05655	PRKCD	S366	G360A	360	Missense	distal	-6	no	9.437	9.364	EPSD	COSMIC	7.604	Down-regulation
AGC_PKC_PKCd_PRKCD_ST	P04637	TP53	Q05655	PRKCD	S366	A364T	364	Missense	proximal	-2	no	9.437	8.285	EPSD	COSMIC	7.604	Down-regulation
AGC_PKC_PKCd_PRKCD_ST	P04637	TP53	Q05655	PRKCD	S366	S366A	366	Missense	central	0	yes	9.437	0.000	EPSD	COSMIC	7.604	Loss
AGC_PKC_PKCd_PRKCD_ST	P04637	TP53	Q05655	PRKCD	S366	G361R	361	Missense	distal	-5	no	9.437	9.851	EPSD	COSMIC	7.604	Up-regulation
AGC_PKC_PKCd_PRKCD_ST	P04637	TP53	Q05655	PRKCD	S366	K370Q	370	Missense	distal	4	no	9.437	8.857	EPSD	COSMIC	7.604	Down-regulation
AGC_PKC_PKCd_PRKCD_ST	P04637	TP53	Q05655	PRKCD	S366	K373R	373	Missense	distal	7	no	9.437	9.409	EPSD	COSMIC	7.604	Down-regulation
AGC_PKC_PKCd_PRKCD_ST	P04637	TP53	Q05655	PRKCD	S366	S371P	371	Missense	distal	5	no	9.437	9.470	EPSD	COSMIC	7.604	Up-regulation
AGC_PKC_PKCd_PRKCD_ST	P04637	TP53	Q05655	PRKCD	S371	S367F	367	Missense	distal	-4	no	9.551	9.681	EPSD	COSMIC	7.604	Up-regulation
AGC_PKC_PKCd_PRKCD_ST	P04637	TP53	Q05655	PRKCD	S371	K370N	370	Missense	proximal	-1	no	9.551	9.370	EPSD	COSMIC	7.604	Down-regulation
AGC_PKC_PKCd_PRKCD_ST	P04637	TP53	Q05655	PRKCD	S371	A364D	364	Missense	distal	-7	no	9.551	9.549	EPSD	COSMIC	7.604	Down-regulation
AGC_PKC_PKCd_PRKCD_ST	P04637	TP53	Q05655	PRKCD	S371	H365Y	365	Missense	distal	-6	no	9.551	9.717	EPSD	COSMIC	7.604	Up-regulation
AGC_PKC_PKCd_PRKCD_ST	P04637	TP53	Q05655	PRKCD	S371	A364T	364	Missense	distal	-7	no	9.551	9.552	EPSD	COSMIC	7.604	Up-regulation
AGC_PKC_PKCd_PRKCD_ST	P04637	TP53	Q05655	PRKCD	S371	S376T	376	Missense	distal	5	no	9.551	9.454	EPSD	COSMIC	7.604	Down-regulation
AGC_PKC_PKCd_PRKCD_ST	P04637	TP53	Q05655	PRKCD	S371	S366A	366	Missense	distal	-5	no	9.551	9.482	EPSD	COSMIC	7.604	Down-regulation
AGC_PKC_PKCd_PRKCD_ST	P04637	TP53	Q05655	PRKCD	S371	T377I	377	Missense	distal	6	no	9.551	9.518	EPSD	COSMIC	7.604	Down-regulation
AGC_PKC_PKCd_PRKCD_ST	P04637	TP53	Q05655	PRKCD	S371	S378F	378	Missense	distal	7	no	9.551	9.503	EPSD	COSMIC	7.604	Down-regulation
AGC_PKC_PKCd_PRKCD_ST	P04637	TP53	Q05655	PRKCD	S371	K370Q	370	Missense	proximal	-1	no	9.551	9.421	EPSD	COSMIC	7.604	Down-regulation
AGC_PKC_PKCd_PRKCD_ST	P04637	TP53	Q05655	PRKCD	S371	K373R	373	Missense	proximal	2	no	9.551	10.728	EPSD	COSMIC	7.604	Up-regulation
AGC_PKC_PKCd_PRKCD_ST	P04637	TP53	Q05655	PRKCD	S371	S376F	376	Missense	distal	5	no	9.551	9.340	EPSD	COSMIC	7.604	Down-regulation
AGC_PKC_PKCd_PRKCD_ST	P04637	TP53	Q05655	PRKCD	S371	G374S	374	Missense	distal	3	no	9.551	9.831	EPSD	COSMIC	7.604	Up-regulation
AGC_PKC_PKCd_PRKCD_ST	P04637	TP53	Q05655	PRKCD	S371	S376A	376	Missense	distal	5	no	9.551	9.415	EPSD	COSMIC	7.604	Down-regulation
AGC_PKC_PKCd_PRKCD_ST	P04637	TP53	Q05655	PRKCD	S371	S371P	371	Missense	central	0	yes	9.551	0.000	EPSD	COSMIC	7.604	Loss
AGC_PKC_PKCd_PRKCD_ST	P04637	TP53	Q05655	PRKCD	S376	K370N	370	Missense	distal	-6	no	8.153	8.603	EPSD	COSMIC	7.604	Up-regulation
AGC_PKC_PKCd_PRKCD_ST	P04637	TP53	Q05655	PRKCD	S376	L383F	383	Missense	distal	7	no	8.153	8.164	EPSD	COSMIC	7.604	Up-regulation
AGC_PKC_PKCd_PRKCD_ST	P04637	TP53	Q05655	PRKCD	S376	R379H	379	Missense	distal	3	no	8.153	7.265	EPSD	COSMIC	7.604	Loss
AGC_PKC_PKCd_PRKCD_ST	P04637	TP53	Q05655	PRKCD	S376	H380Y	380	Missense	distal	4	no	8.153	7.899	EPSD	COSMIC	7.604	Down-regulation
AGC_PKC_PKCd_PRKCD_ST	P04637	TP53	Q05655	PRKCD	S376	T377I	377	Missense	proximal	1	no	8.153	8.066	EPSD	COSMIC	7.604	Down-regulation
AGC_PKC_PKCd_PRKCD_ST	P04637	TP53	Q05655	PRKCD	S376	S378F	378	Missense	proximal	2	no	8.153	8.096	EPSD	COSMIC	7.604	Down-regulation
AGC_PKC_PKCd_PRKCD_ST	P04637	TP53	Q05655	PRKCD	S376	K370Q	370	Missense	distal	-6	no	8.153	8.505	EPSD	COSMIC	7.604	Up-regulation
AGC_PKC_PKCd_PRKCD_ST	P04637	TP53	Q05655	PRKCD	S376	K381N	381	Missense	distal	5	no	8.153	7.644	EPSD	COSMIC	7.604	Down-regulation
AGC_PKC_PKCd_PRKCD_ST	P04637	TP53	Q05655	PRKCD	S376	R379P	379	Missense	distal	3	no	8.153	7.290	EPSD	COSMIC	7.604	Loss
AGC_PKC_PKCd_PRKCD_ST	P04637	TP53	Q05655	PRKCD	S376	K373R	373	Missense	distal	-3	no	8.153	9.188	EPSD	COSMIC	7.604	Up-regulation
AGC_PKC_PKCd_PRKCD_ST	P04637	TP53	Q05655	PRKCD	S376	S376F	376	Missense	central	0	yes	8.153	0.000	EPSD	COSMIC	7.604	Loss
AGC_PKC_PKCd_PRKCD_ST	P04637	TP53	Q05655	PRKCD	S376	G374S	374	Missense	proximal	-2	no	8.153	9.068	EPSD	COSMIC	7.604	Up-regulation
AGC_PKC_PKCd_PRKCD_ST	P04637	TP53	Q05655	PRKCD	S376	S376A	376	Missense	central	0	yes	8.153	0.000	EPSD	COSMIC	7.604	Loss
AGC_PKC_PKCd_PRKCD_ST	P04637	TP53	Q05655	PRKCD	S376	S371P	371	Missense	distal	-5	no	8.153	8.144	EPSD	COSMIC	7.604	Down-regulation
AGC_PKC_PKCd_PRKCD_ST	P04637	TP53	Q05655	PRKCD	T377	K370N	370	Missense	distal	-7	no	8.421	8.397	EPSD	COSMIC	7.604	Down-regulation
AGC_PKC_PKCd_PRKCD_ST	P04637	TP53	Q05655	PRKCD	T377	L383F	383	Missense	distal	6	no	8.421	8.424	EPSD	COSMIC	7.604	Up-regulation
AGC_PKC_PKCd_PRKCD_ST	P04637	TP53	Q05655	PRKCD	T377	R379H	379	Missense	proximal	2	no	8.421	2.861	EPSD	COSMIC	7.604	Loss
AGC_PKC_PKCd_PRKCD_ST	P04637	TP53	Q05655	PRKCD	T377	S376T	376	Missense	proximal	-1	no	8.421	8.360	EPSD	COSMIC	7.604	Down-regulation
AGC_PKC_PKCd_PRKCD_ST	P04637	TP53	Q05655	PRKCD	T377	H380Y	380	Missense	distal	3	no	8.421	7.975	EPSD	COSMIC	7.604	Down-regulation
AGC_PKC_PKCd_PRKCD_ST	P04637	TP53	Q05655	PRKCD	T377	T377I	377	Missense	central	0	yes	8.421	0.000	EPSD	COSMIC	7.604	Loss
AGC_PKC_PKCd_PRKCD_ST	P04637	TP53	Q05655	PRKCD	T377	S378F	378	Missense	proximal	1	no	8.421	8.372	EPSD	COSMIC	7.604	Down-regulation
AGC_PKC_PKCd_PRKCD_ST	P04637	TP53	Q05655	PRKCD	T377	K370Q	370	Missense	distal	-7	no	8.421	8.403	EPSD	COSMIC	7.604	Down-regulation
AGC_PKC_PKCd_PRKCD_ST	P04637	TP53	Q05655	PRKCD	T377	K381N	381	Missense	distal	4	no	8.421	7.776	EPSD	COSMIC	7.604	Down-regulation
AGC_PKC_PKCd_PRKCD_ST	P04637	TP53	Q05655	PRKCD	T377	R379P	379	Missense	proximal	2	no	8.421	2.603	EPSD	COSMIC	7.604	Loss
AGC_PKC_PKCd_PRKCD_ST	P04637	TP53	Q05655	PRKCD	T377	M384I	384	Missense	distal	7	no	8.421	8.411	EPSD	COSMIC	7.604	Down-regulation
AGC_PKC_PKCd_PRKCD_ST	P04637	TP53	Q05655	PRKCD	T377	K373R	373	Missense	distal	-4	no	8.421	8.447	EPSD	COSMIC	7.604	Up-regulation
AGC_PKC_PKCd_PRKCD_ST	P04637	TP53	Q05655	PRKCD	T377	S376F	376	Missense	proximal	-1	no	8.421	8.315	EPSD	COSMIC	7.604	Down-regulation
AGC_PKC_PKCd_PRKCD_ST	P04637	TP53	Q05655	PRKCD	T377	G374S	374	Missense	distal	-3	no	8.421	9.055	EPSD	COSMIC	7.604	Up-regulation
AGC_PKC_PKCd_PRKCD_ST	P04637	TP53	Q05655	PRKCD	T377	S376A	376	Missense	proximal	-1	no	8.421	8.344	EPSD	COSMIC	7.604	Down-regulation
AGC_PKC_PKCd_PRKCD_ST	P04637	TP53	Q05655	PRKCD	T377	S371P	371	Missense	distal	-6	no	8.421	8.498	EPSD	COSMIC	7.604	Up-regulation
AGC_PKC_PKCd_PRKCD_ST	P06401	PGR	Q05655	PRKCD	S20	E22K	22	Missense	proximal	2	no	3.379	9.135	EPSD	COSMIC	7.604	Gain
AGC_PKC_PKCd_PRKCD_ST	P06401	PGR	Q05655	PRKCD	S190	R187W	187	Missense	distal	-3	no	9.830	4.533	EPSD	COSMIC	7.604	Loss
AGC_PKC_PKCd_PRKCD_ST	P06401	PGR	Q05655	PRKCD	S190	R187L	187	Missense	distal	-3	no	9.830	4.643	EPSD	COSMIC;CCLE	7.604	Loss
AGC_PKC_PKCd_PRKCD_ST	P06401	PGR	Q05655	PRKCD	S273	E271K	271	Missense	proximal	-2	no	6.703	11.684	EPSD	COSMIC	7.604	Gain
AGC_PKC_PKCd_PRKCD_ST	P06401	PGR	Q05655	PRKCD	S276	E271K	271	Missense	distal	-5	no	10.275	10.633	EPSD	COSMIC	7.604	Up-regulation
AGC_PKC_PKCd_PRKCD_ST	P06401	PGR	Q05655	PRKCD	S276	A277V	277	Missense	proximal	1	no	10.275	10.259	EPSD	COSMIC	7.604	Down-regulation
AGC_PKC_PKCd_PRKCD_ST	P06401	PGR	Q05655	PRKCD	S276	V283E	283	Missense	distal	7	no	10.275	10.294	EPSD	COSMIC	7.604	Up-regulation
AGC_PKC_PKCd_PRKCD_ST	P06401	PGR	Q05655	PRKCD	S276	L282F	282	Missense	distal	6	no	10.275	10.278	EPSD	COSMIC	7.604	Up-regulation
AGC_PKC_PKCd_PRKCD_ST	P06401	PGR	Q05655	PRKCD	S345	C347G	347	Missense	proximal	2	no	7.444	7.991	EPSD	COSMIC	7.604	Gain
AGC_PKC_PKCd_PRKCD_ST	P06401	PGR	Q05655	PRKCD	S397	R399C	399	Missense	proximal	2	no	8.825	1.946	EPSD	COSMIC	7.604	Loss
AGC_PKC_PKCd_PRKCD_ST	P06401	PGR	Q05655	PRKCD	S397	E390G	390	Missense	distal	-7	no	8.825	8.823	EPSD	COSMIC	7.604	Down-regulation
AGC_PKC_PKCd_PRKCD_ST	P06401	PGR	Q05655	PRKCD	S397	R399S	399	Missense	proximal	2	no	8.825	2.762	EPSD	COSMIC	7.604	Loss
AGC_PKC_PKCd_PRKCD_ST	P06401	PGR	Q05655	PRKCD	S397	R402C	402	Missense	distal	5	no	8.825	8.260	EPSD	COSMIC	7.604	Down-regulation
AGC_PKC_PKCd_PRKCD_ST	P06401	PGR	Q05655	PRKCD	S397	P401L	401	Missense	distal	4	no	8.825	8.620	EPSD	COSMIC	7.604	Down-regulation
AGC_PKC_PKCd_PRKCD_ST	P06401	PGR	Q05655	PRKCD	S397	R402H	402	Missense	distal	5	no	8.825	8.473	EPSD	COSMIC	7.604	Down-regulation
AGC_PKC_PKCd_PRKCD_ST	P06401	PGR	Q05655	PRKCD	S397	E391K	391	Missense	distal	-6	no	8.825	8.406	EPSD	COSMIC	7.604	Down-regulation
AGC_PKC_PKCd_PRKCD_ST	P06401	PGR	Q05655	PRKCD	S400	R399C	399	Missense	proximal	-1	no	10.978	10.767	PhosphoSitePlus	COSMIC	7.604	Down-regulation
AGC_PKC_PKCd_PRKCD_ST	P06401	PGR	Q05655	PRKCD	S400	R399S	399	Missense	proximal	-1	no	10.978	10.904	PhosphoSitePlus	COSMIC	7.604	Down-regulation
AGC_PKC_PKCd_PRKCD_ST	P06401	PGR	Q05655	PRKCD	S400	R402C	402	Missense	proximal	2	no	10.978	4.099	PhosphoSitePlus	COSMIC	7.604	Loss
AGC_PKC_PKCd_PRKCD_ST	P06401	PGR	Q05655	PRKCD	S400	P401L	401	Missense	proximal	1	no	10.978	10.903	PhosphoSitePlus	COSMIC	7.604	Down-regulation
AGC_PKC_PKCd_PRKCD_ST	P06401	PGR	Q05655	PRKCD	S400	R402H	402	Missense	proximal	2	no	10.978	5.417	PhosphoSitePlus	COSMIC	7.604	Loss
AGC_PKC_PKCd_PRKCD_ST	P06401	PGR	Q05655	PRKCD	S549	L542V	542	Missense	distal	-7	no	9.693	9.692	EPSD	COSMIC	7.604	Down-regulation
AGC_PKC_PKCd_PRKCD_ST	P06401	PGR	Q05655	PRKCD	S549	L545M	545	Missense	distal	-4	no	9.693	9.694	EPSD	COSMIC	7.604	Up-regulation
AGC_PKC_PKCd_PRKCD_ST	P06401	PGR	Q05655	PRKCD	S549	P547L	547	Missense	proximal	-2	no	9.693	8.023	EPSD	COSMIC	7.604	Down-regulation
AGC_PKC_PKCd_PRKCD_ST	Q8TCU6	PREX1	Q05655	PRKCD	S43	R50C	50	Missense	distal	7	no	15.026	14.889	EPSD	COSMIC;GDSC;CCLE	7.604	Down-regulation
AGC_PKC_PKCd_PRKCD_ST	Q8TCU6	PREX1	Q05655	PRKCD	T308	G309R	309	Missense	proximal	1	no	8.800	9.001	EPSD	COSMIC	7.604	Up-regulation
AGC_PKC_PKCd_PRKCD_ST	Q8TCU6	PREX1	Q05655	PRKCD	T308	G309W	309	Missense	proximal	1	no	8.800	8.720	EPSD	COSMIC;CCLE	7.604	Down-regulation
AGC_PKC_PKCd_PRKCD_ST	Q8TCU6	PREX1	Q05655	PRKCD	S310	G309R	309	Missense	proximal	-1	no	7.760	7.937	EPSD	COSMIC	7.604	Up-regulation
AGC_PKC_PKCd_PRKCD_ST	Q8TCU6	PREX1	Q05655	PRKCD	S310	G309W	309	Missense	proximal	-1	no	7.760	7.665	EPSD	COSMIC;CCLE	7.604	Down-regulation
AGC_PKC_PKCd_PRKCD_ST	Q8TCU6	PREX1	Q05655	PRKCD	S313	G309R	309	Missense	distal	-4	no	13.449	13.065	PhosphoSitePlus	COSMIC	7.604	Down-regulation
AGC_PKC_PKCd_PRKCD_ST	Q8TCU6	PREX1	Q05655	PRKCD	S313	S319A	319	Missense	distal	6	no	13.449	13.432	PhosphoSitePlus	COSMIC	7.604	Down-regulation
AGC_PKC_PKCd_PRKCD_ST	Q8TCU6	PREX1	Q05655	PRKCD	S313	G309W	309	Missense	distal	-4	no	13.449	13.596	PhosphoSitePlus	COSMIC;CCLE	7.604	Up-regulation
AGC_PKC_PKCd_PRKCD_ST	Q8TCU6	PREX1	Q05655	PRKCD	T314	G309R	309	Missense	distal	-5	no	15.960	16.374	EPSD	COSMIC	7.604	Up-regulation
AGC_PKC_PKCd_PRKCD_ST	Q8TCU6	PREX1	Q05655	PRKCD	T314	S319A	319	Missense	distal	5	no	15.960	15.824	EPSD	COSMIC	7.604	Down-regulation
AGC_PKC_PKCd_PRKCD_ST	Q8TCU6	PREX1	Q05655	PRKCD	T314	G309W	309	Missense	distal	-5	no	15.960	15.829	EPSD	COSMIC;CCLE	7.604	Down-regulation
AGC_PKC_PKCd_PRKCD_ST	Q8TCU6	PREX1	Q05655	PRKCD	S436	R431C	431	Missense	distal	-5	no	12.642	12.166	EPSD	COSMIC	7.604	Down-regulation
AGC_PKC_PKCd_PRKCD_ST	Q8TCU6	PREX1	Q05655	PRKCD	S834	S828F	828	Missense	distal	-6	no	7.442	7.647	EPSD	COSMIC	7.604	Gain
AGC_PKC_PKCd_PRKCD_ST	Q8TCU6	PREX1	Q05655	PRKCD	S993	G989D	989	Missense	distal	-4	no	14.544	14.521	EPSD	COSMIC	7.604	Down-regulation
AGC_PKC_PKCd_PRKCD_ST	Q8TCU6	PREX1	Q05655	PRKCD	S993	R998H	998	Missense	distal	5	no	14.544	14.192	EPSD	COSMIC	7.604	Down-regulation
AGC_PKC_PKCd_PRKCD_ST	Q8TCU6	PREX1	Q05655	PRKCD	S993	P986L	986	Missense	distal	-7	no	14.544	14.533	EPSD	COSMIC	7.604	Down-regulation
AGC_PKC_PKCd_PRKCD_ST	Q8TCU6	PREX1	Q05655	PRKCD	S993	R990M	990	Missense	distal	-3	no	14.544	9.721	EPSD	COSMIC;GDSC;CCLE	7.604	Down-regulation
AGC_PKC_PKCd_PRKCD_ST	Q8TCU6	PREX1	Q05655	PRKCD	S1001	R998H	998	Missense	distal	-3	no	11.614	7.359	EPSD	COSMIC	7.604	Loss
AGC_PKC_PKCd_PRKCD_ST	Q8TCU6	PREX1	Q05655	PRKCD	S1001	P1007A	1007	Missense	distal	6	no	11.614	11.602	EPSD	COSMIC	7.604	Down-regulation
AGC_PKC_PKCd_PRKCD_ST	Q8TCU6	PREX1	Q05655	PRKCD	S1049	G1051R	1051	Missense	proximal	2	no	2.069	8.400	EPSD	COSMIC	7.604	Gain
AGC_PKC_PKCd_PRKCD_ST	Q8TCU6	PREX1	Q05655	PRKCD	S1054	G1051R	1051	Missense	distal	-3	no	3.652	8.861	EPSD	COSMIC	7.604	Gain
AGC_PKC_PKCd_PRKCD_ST	P12830	CDH1	Q05655	PRKCD	T217	L214R	214	Missense	distal	-3	no	4.344	9.531	EPSD	COSMIC	7.604	Gain
AGC_PKC_PKCd_PRKCD_ST	P12830	CDH1	Q05655	PRKCD	S237	G239R	239	Missense	proximal	2	no	3.217	9.548	EPSD	COSMIC	7.604	Gain
AGC_PKC_PKCd_PRKCD_ST	P12830	CDH1	Q05655	PRKCD	S853	D858E	858	Missense	distal	5	no	8.160	8.176	EPSD	COSMIC	7.604	Up-regulation
AGC_PKC_PKCd_PRKCD_ST	P12830	CDH1	Q05655	PRKCD	S853	E852D	852	Missense	proximal	-1	no	8.160	8.178	EPSD	COSMIC	7.604	Up-regulation
AGC_PKC_PKCd_PRKCD_ST	P12830	CDH1	Q05655	PRKCD	S853	S853P	853	Missense	central	0	yes	8.160	0.000	EPSD	COSMIC	7.604	Loss
AGC_PKC_PKCd_PRKCD_ST	P12830	CDH1	Q05655	PRKCD	S853	D854Y	854	Missense	proximal	1	no	8.160	8.120	EPSD	COSMIC	7.604	Down-regulation
AGC_PKC_PKCd_PRKCD_ST	P12830	CDH1	Q05655	PRKCD	S853	Y859C	859	Missense	distal	6	no	8.160	8.158	EPSD	COSMIC	7.604	Down-regulation
AGC_PKC_PKCd_PRKCD_ST	P12830	CDH1	Q05655	PRKCD	S853	S847F	847	Missense	distal	-6	no	8.160	8.365	EPSD	COSMIC	7.604	Up-regulation
AGC_PKC_PKCd_PRKCD_ST	P12830	CDH1	Q05655	PRKCD	S853	E852K	852	Missense	proximal	-1	no	8.160	8.334	EPSD	COSMIC	7.604	Up-regulation
AGC_PKC_PKCd_PRKCD_ST	P12830	CDH1	Q05655	PRKCD	S853	S846T	846	Missense	distal	-7	no	8.160	8.155	EPSD	COSMIC	7.604	Down-regulation
AGC_PKC_PKCd_PRKCD_ST	P12830	CDH1	Q05655	PRKCD	S853	Q857K	857	Missense	distal	4	no	8.160	8.740	EPSD	COSMIC	7.604	Up-regulation
AGC_PKC_PKCd_PRKCD_ST	P12830	CDH1	Q05655	PRKCD	S853	S851L	851	Missense	proximal	-2	no	8.160	6.875	EPSD	COSMIC	7.604	Loss
AGC_PKC_PKCd_PRKCD_ST	P21730	C5AR1	Q05655	PRKCD	S332	E331K	331	Missense	proximal	-1	no	9.823	9.997	EPSD	COSMIC	7.604	Up-regulation
AGC_PKC_PKCd_PRKCD_ST	P21730	C5AR1	Q05655	PRKCD	S332	T336M	336	Missense	distal	4	no	9.823	9.647	EPSD	COSMIC	7.604	Down-regulation
AGC_PKC_PKCd_PRKCD_ST	P21730	C5AR1	Q05655	PRKCD	S334	E331K	331	Missense	distal	-3	no	4.065	8.450	PhosphoSitePlus	COSMIC	7.604	Gain
AGC_PKC_PKCd_PRKCD_ST	P35568	IRS1	Q05655	PRKCD	S24	K27R	27	Missense	distal	3	no	11.075	11.068	EPSD	COSMIC	7.604	Down-regulation
AGC_PKC_PKCd_PRKCD_ST	P35568	IRS1	Q05655	PRKCD	S24	V31I	31	Missense	distal	7	no	11.075	11.070	EPSD	COSMIC	7.604	Down-regulation
AGC_PKC_PKCd_PRKCD_ST	P35568	IRS1	Q05655	PRKCD	S24	G17C	17	Missense	distal	-7	no	11.075	11.071	EPSD	COSMIC	7.604	Down-regulation
AGC_PKC_PKCd_PRKCD_ST	P35568	IRS1	Q05655	PRKCD	S36	G39R	39	Missense	distal	3	no	7.588	8.725	EPSD	COSMIC	7.604	Gain
AGC_PKC_PKCd_PRKCD_ST	P35568	IRS1	Q05655	PRKCD	S268	R265C	265	Missense	distal	-3	no	8.493	3.173	EPSD	COSMIC	7.604	Loss
AGC_PKC_PKCd_PRKCD_ST	P35568	IRS1	Q05655	PRKCD	S268	S274P	274	Missense	distal	6	no	8.493	8.487	EPSD	COSMIC	7.604	Down-regulation
AGC_PKC_PKCd_PRKCD_ST	P35568	IRS1	Q05655	PRKCD	S270	R265C	265	Missense	distal	-5	no	9.706	9.229	EPSD	COSMIC	7.604	Down-regulation
AGC_PKC_PKCd_PRKCD_ST	P35568	IRS1	Q05655	PRKCD	S270	S274P	274	Missense	distal	4	no	9.706	9.744	EPSD	COSMIC	7.604	Up-regulation
AGC_PKC_PKCd_PRKCD_ST	P35568	IRS1	Q05655	PRKCD	S272	S274P	274	Missense	proximal	2	no	7.493	7.738	EPSD	COSMIC	7.604	Gain
AGC_PKC_PKCd_PRKCD_ST	P35568	IRS1	Q05655	PRKCD	S307	R301C	301	Missense	distal	-6	no	8.043	8.513	EPSD;PhosphoSitePlus	COSMIC	7.604	Up-regulation
AGC_PKC_PKCd_PRKCD_ST	P35568	IRS1	Q05655	PRKCD	S307	E306K	306	Missense	proximal	-1	no	8.043	8.216	EPSD;PhosphoSitePlus	COSMIC	7.604	Up-regulation
AGC_PKC_PKCd_PRKCD_ST	P35568	IRS1	Q05655	PRKCD	S307	A310T	310	Missense	distal	3	no	8.043	7.967	EPSD;PhosphoSitePlus	COSMIC	7.604	Down-regulation
AGC_PKC_PKCd_PRKCD_ST	P35568	IRS1	Q05655	PRKCD	S307	P313L	313	Missense	distal	6	no	8.043	8.019	EPSD;PhosphoSitePlus	COSMIC;GDSC;CCLE	7.604	Down-regulation
AGC_PKC_PKCd_PRKCD_ST	P35568	IRS1	Q05655	PRKCD	S307	R302L	302	Missense	distal	-5	no	8.043	7.613	EPSD;PhosphoSitePlus	COSMIC	7.604	Down-regulation
AGC_PKC_PKCd_PRKCD_ST	P35568	IRS1	Q05655	PRKCD	S307	I308M	308	Missense	proximal	1	no	8.043	8.053	EPSD;PhosphoSitePlus	COSMIC	7.604	Up-regulation
AGC_PKC_PKCd_PRKCD_ST	P35568	IRS1	Q05655	PRKCD	S307	A310V	310	Missense	distal	3	no	8.043	7.810	EPSD;PhosphoSitePlus	COSMIC	7.604	Down-regulation
AGC_PKC_PKCd_PRKCD_ST	P35568	IRS1	Q05655	PRKCD	S323	R327L	327	Missense	distal	4	no	13.662	13.026	EPSD;PhosphoSitePlus	COSMIC	7.604	Down-regulation
AGC_PKC_PKCd_PRKCD_ST	P35568	IRS1	Q05655	PRKCD	S323	R325H	325	Missense	proximal	2	no	13.662	8.101	EPSD;PhosphoSitePlus	COSMIC;CCLE	7.604	Down-regulation
AGC_PKC_PKCd_PRKCD_ST	P35568	IRS1	Q05655	PRKCD	S323	R327C	327	Missense	distal	4	no	13.662	12.866	EPSD;PhosphoSitePlus	COSMIC;CCLE	7.604	Down-regulation
AGC_PKC_PKCd_PRKCD_ST	P35568	IRS1	Q05655	PRKCD	S323	M316I	316	Missense	distal	-7	no	13.662	13.660	EPSD;PhosphoSitePlus	COSMIC	7.604	Down-regulation
AGC_PKC_PKCd_PRKCD_ST	P35568	IRS1	Q05655	PRKCD	S323	R325C	325	Missense	proximal	2	no	13.662	6.783	EPSD;PhosphoSitePlus	COSMIC	7.604	Loss
AGC_PKC_PKCd_PRKCD_ST	P35568	IRS1	Q05655	PRKCD	S323	F324L	324	Missense	proximal	1	no	13.662	13.656	EPSD;PhosphoSitePlus	COSMIC	7.604	Down-regulation
AGC_PKC_PKCd_PRKCD_ST	P35568	IRS1	Q05655	PRKCD	S330	E333K	333	Missense	distal	3	no	7.064	8.246	EPSD	COSMIC	7.604	Gain
AGC_PKC_PKCd_PRKCD_ST	P35568	IRS1	Q05655	PRKCD	S330	G332R	332	Missense	proximal	2	no	7.064	13.396	EPSD	COSMIC	7.604	Gain
AGC_PKC_PKCd_PRKCD_ST	P35568	IRS1	Q05655	PRKCD	S341	S341L	341	Missense	central	0	yes	7.893	0.000	EPSD	COSMIC	7.604	Loss
AGC_PKC_PKCd_PRKCD_ST	P35568	IRS1	Q05655	PRKCD	S341	P346S	346	Missense	distal	5	no	7.893	7.861	EPSD	COSMIC	7.604	Down-regulation
AGC_PKC_PKCd_PRKCD_ST	P35568	IRS1	Q05655	PRKCD	T351	A356P	356	Missense	distal	5	no	7.871	8.039	EPSD	COSMIC	7.604	Up-regulation
AGC_PKC_PKCd_PRKCD_ST	P35568	IRS1	Q05655	PRKCD	T351	R358Q	358	Missense	distal	7	no	7.871	7.780	EPSD	COSMIC	7.604	Down-regulation
AGC_PKC_PKCd_PRKCD_ST	P35568	IRS1	Q05655	PRKCD	T351	N352D	352	Missense	proximal	1	no	7.871	7.878	EPSD	COSMIC	7.604	Up-regulation
AGC_PKC_PKCd_PRKCD_ST	P35568	IRS1	Q05655	PRKCD	T351	P349L	349	Missense	proximal	-2	no	7.871	6.201	EPSD	COSMIC	7.604	Loss
AGC_PKC_PKCd_PRKCD_ST	P35568	IRS1	Q05655	PRKCD	T351	P346S	346	Missense	distal	-5	no	7.871	7.879	EPSD	COSMIC	7.604	Up-regulation
AGC_PKC_PKCd_PRKCD_ST	P35568	IRS1	Q05655	PRKCD	S362	L369F	369	Missense	distal	7	no	14.525	14.536	EPSD	COSMIC	7.604	Up-regulation
AGC_PKC_PKCd_PRKCD_ST	P35568	IRS1	Q05655	PRKCD	S362	A356P	356	Missense	distal	-6	no	14.525	14.484	EPSD	COSMIC	7.604	Down-regulation
AGC_PKC_PKCd_PRKCD_ST	P35568	IRS1	Q05655	PRKCD	S362	R364Q	364	Missense	proximal	2	no	14.525	7.736	EPSD	COSMIC	7.604	Down-regulation
AGC_PKC_PKCd_PRKCD_ST	P35568	IRS1	Q05655	PRKCD	S362	R358Q	358	Missense	distal	-4	no	14.525	14.840	EPSD	COSMIC	7.604	Up-regulation
AGC_PKC_PKCd_PRKCD_ST	P35568	IRS1	Q05655	PRKCD	S362	G361S	361	Missense	proximal	-1	no	14.525	14.628	EPSD	COSMIC	7.604	Up-regulation
AGC_PKC_PKCd_PRKCD_ST	P35568	IRS1	Q05655	PRKCD	S383	A379P	379	Missense	distal	-4	no	7.873	7.812	EPSD	COSMIC	7.604	Down-regulation
AGC_PKC_PKCd_PRKCD_ST	P35568	IRS1	Q05655	PRKCD	S383	S383L	383	Missense	central	0	yes	7.873	0.000	EPSD	COSMIC	7.604	Loss
AGC_PKC_PKCd_PRKCD_ST	P35568	IRS1	Q05655	PRKCD	S383	R381L	381	Missense	proximal	-2	no	7.873	1.740	EPSD	COSMIC	7.604	Loss
AGC_PKC_PKCd_PRKCD_ST	P35568	IRS1	Q05655	PRKCD	S383	S383W	383	Missense	central	0	yes	7.873	0.000	EPSD	COSMIC	7.604	Loss
AGC_PKC_PKCd_PRKCD_ST	P35568	IRS1	Q05655	PRKCD	S383	P384S	384	Missense	proximal	1	no	7.873	7.853	EPSD	COSMIC	7.604	Down-regulation
AGC_PKC_PKCd_PRKCD_ST	P35568	IRS1	Q05655	PRKCD	S383	S385L	385	Missense	proximal	2	no	7.873	7.059	EPSD	COSMIC	7.604	Loss
AGC_PKC_PKCd_PRKCD_ST	P35568	IRS1	Q05655	PRKCD	S412	S415L	415	Missense	distal	3	no	8.948	8.661	EPSD	COSMIC	7.604	Down-regulation
AGC_PKC_PKCd_PRKCD_ST	P35568	IRS1	Q05655	PRKCD	S412	G418V	418	Missense	distal	6	no	8.948	8.939	EPSD	COSMIC;GDSC;CCLE	7.604	Down-regulation
AGC_PKC_PKCd_PRKCD_ST	P35568	IRS1	Q05655	PRKCD	S413	S415L	415	Missense	proximal	2	no	12.056	11.242	EPSD	COSMIC	7.604	Down-regulation
AGC_PKC_PKCd_PRKCD_ST	P35568	IRS1	Q05655	PRKCD	S413	G418V	418	Missense	distal	5	no	12.056	12.014	EPSD	COSMIC;GDSC;CCLE	7.604	Down-regulation
AGC_PKC_PKCd_PRKCD_ST	P35568	IRS1	Q05655	PRKCD	S441	P435L	435	Missense	distal	-6	no	14.704	14.873	EPSD;PhosphoSitePlus	COSMIC	7.604	Up-regulation
AGC_PKC_PKCd_PRKCD_ST	P35568	IRS1	Q05655	PRKCD	S441	R439Q	439	Missense	proximal	-2	no	14.704	9.269	EPSD;PhosphoSitePlus	COSMIC	7.604	Down-regulation
AGC_PKC_PKCd_PRKCD_ST	P35568	IRS1	Q05655	PRKCD	S441	D448E	448	Missense	distal	7	no	14.704	14.701	EPSD;PhosphoSitePlus	COSMIC	7.604	Down-regulation
AGC_PKC_PKCd_PRKCD_ST	P35568	IRS1	Q05655	PRKCD	S441	S441Y	441	Missense	central	0	yes	14.704	0.000	EPSD;PhosphoSitePlus	COSMIC	7.604	Loss
AGC_PKC_PKCd_PRKCD_ST	P35568	IRS1	Q05655	PRKCD	S441	S434G	434	Missense	distal	-7	no	14.704	14.693	EPSD;PhosphoSitePlus	COSMIC	7.604	Down-regulation
AGC_PKC_PKCd_PRKCD_ST	P35568	IRS1	Q05655	PRKCD	S441	S441F	441	Missense	central	0	yes	14.704	0.000	EPSD;PhosphoSitePlus	COSMIC	7.604	Loss
AGC_PKC_PKCd_PRKCD_ST	P35568	IRS1	Q05655	PRKCD	S441	R443C	443	Missense	proximal	2	no	14.704	7.825	EPSD;PhosphoSitePlus	COSMIC	7.604	Down-regulation
AGC_PKC_PKCd_PRKCD_ST	P35568	IRS1	Q05655	PRKCD	S441	P435F	435	Missense	distal	-6	no	14.704	14.832	EPSD;PhosphoSitePlus	COSMIC	7.604	Up-regulation
AGC_PKC_PKCd_PRKCD_ST	P35568	IRS1	Q05655	PRKCD	S441	P447L	447	Missense	distal	6	no	14.704	14.680	EPSD;PhosphoSitePlus	COSMIC	7.604	Down-regulation
AGC_PKC_PKCd_PRKCD_ST	P35568	IRS1	Q05655	PRKCD	S441	R443L	443	Missense	proximal	2	no	14.704	7.826	EPSD;PhosphoSitePlus	COSMIC	7.604	Down-regulation
AGC_PKC_PKCd_PRKCD_ST	P35568	IRS1	Q05655	PRKCD	S441	S444I	444	Missense	distal	3	no	14.704	14.249	EPSD;PhosphoSitePlus	COSMIC	7.604	Down-regulation
AGC_PKC_PKCd_PRKCD_ST	P35568	IRS1	Q05655	PRKCD	T525	T530A	530	Missense	distal	5	no	10.973	10.933	EPSD	COSMIC	7.604	Down-regulation
AGC_PKC_PKCd_PRKCD_ST	P35568	IRS1	Q05655	PRKCD	T525	R520L	520	Missense	distal	-5	no	10.973	10.543	EPSD	COSMIC	7.604	Down-regulation
AGC_PKC_PKCd_PRKCD_ST	P35568	IRS1	Q05655	PRKCD	T525	F521I	521	Missense	distal	-4	no	10.973	11.052	EPSD	COSMIC	7.604	Up-regulation
AGC_PKC_PKCd_PRKCD_ST	P35568	IRS1	Q05655	PRKCD	T525	H526Y	526	Missense	proximal	1	no	10.973	10.896	EPSD	COSMIC	7.604	Down-regulation
AGC_PKC_PKCd_PRKCD_ST	P35568	IRS1	Q05655	PRKCD	T525	G529D	529	Missense	distal	4	no	10.973	11.012	EPSD	COSMIC	7.604	Up-regulation
AGC_PKC_PKCd_PRKCD_ST	P35568	IRS1	Q05655	PRKCD	T535	Q537R	537	Missense	proximal	2	no	1.516	8.306	EPSD	COSMIC	7.604	Gain
AGC_PKC_PKCd_PRKCD_ST	P35568	IRS1	Q05655	PRKCD	S603	H598R	598	Missense	distal	-5	no	8.411	8.747	EPSD	COSMIC	7.604	Up-regulation
AGC_PKC_PKCd_PRKCD_ST	P35568	IRS1	Q05655	PRKCD	S603	G596E	596	Missense	distal	-7	no	8.411	8.413	EPSD	COSMIC	7.604	Up-regulation
AGC_PKC_PKCd_PRKCD_ST	P35568	IRS1	Q05655	PRKCD	S603	H599Y	599	Missense	distal	-4	no	8.411	8.572	EPSD	COSMIC	7.604	Up-regulation
AGC_PKC_PKCd_PRKCD_ST	P35568	IRS1	Q05655	PRKCD	S603	H599Q	599	Missense	distal	-4	no	8.411	8.434	EPSD	COSMIC	7.604	Up-regulation
AGC_PKC_PKCd_PRKCD_ST	P35568	IRS1	Q05655	PRKCD	S624	G628D	628	Missense	distal	4	no	8.167	8.207	EPSD	COSMIC	7.604	Up-regulation
AGC_PKC_PKCd_PRKCD_ST	P35568	IRS1	Q05655	PRKCD	S624	R626Q	626	Missense	proximal	2	no	8.167	1.378	EPSD	COSMIC	7.604	Loss
AGC_PKC_PKCd_PRKCD_ST	P35568	IRS1	Q05655	PRKCD	S624	V622M	622	Missense	proximal	-2	no	8.167	8.061	EPSD	COSMIC	7.604	Down-regulation
AGC_PKC_PKCd_PRKCD_ST	P35568	IRS1	Q05655	PRKCD	S624	G630E	630	Missense	distal	6	no	8.167	8.174	EPSD	COSMIC	7.604	Up-regulation
AGC_PKC_PKCd_PRKCD_ST	P35568	IRS1	Q05655	PRKCD	S629	G628D	628	Missense	proximal	-1	no	9.763	9.779	EPSD	COSMIC	7.604	Up-regulation
AGC_PKC_PKCd_PRKCD_ST	P35568	IRS1	Q05655	PRKCD	S629	R626Q	626	Missense	distal	-3	no	9.763	4.606	EPSD	COSMIC	7.604	Loss
AGC_PKC_PKCd_PRKCD_ST	P35568	IRS1	Q05655	PRKCD	S629	G630E	630	Missense	proximal	1	no	9.763	9.821	EPSD	COSMIC	7.604	Up-regulation
AGC_PKC_PKCd_PRKCD_ST	P35568	IRS1	Q05655	PRKCD	S636	V640I	640	Missense	distal	4	no	10.727	10.661	EPSD	COSMIC;GDSC;CCLE	7.604	Down-regulation
AGC_PKC_PKCd_PRKCD_ST	P35568	IRS1	Q05655	PRKCD	S636	A642T	642	Missense	distal	6	no	10.727	10.739	EPSD	COSMIC	7.604	Up-regulation
AGC_PKC_PKCd_PRKCD_ST	P35568	IRS1	Q05655	PRKCD	S636	G630E	630	Missense	distal	-6	no	10.727	10.704	EPSD	COSMIC	7.604	Down-regulation
AGC_PKC_PKCd_PRKCD_ST	P35568	IRS1	Q05655	PRKCD	S792	R785Q	785	Missense	distal	-7	no	8.515	8.499	EPSD	COSMIC	7.604	Down-regulation
AGC_PKC_PKCd_PRKCD_ST	P35568	IRS1	Q05655	PRKCD	S792	S792F	792	Missense	central	0	yes	8.515	0.000	EPSD	COSMIC	7.604	Loss
AGC_PKC_PKCd_PRKCD_ST	P35568	IRS1	Q05655	PRKCD	S792	R790C	790	Missense	proximal	-2	no	8.515	2.521	EPSD	COSMIC	7.604	Loss
AGC_PKC_PKCd_PRKCD_ST	P35568	IRS1	Q05655	PRKCD	S792	Q787R	787	Missense	distal	-5	no	8.515	8.866	EPSD	COSMIC	7.604	Up-regulation
AGC_PKC_PKCd_PRKCD_ST	P35568	IRS1	Q05655	PRKCD	S795	S792F	792	Missense	distal	-3	no	7.681	7.733	EPSD	COSMIC	7.604	Up-regulation
AGC_PKC_PKCd_PRKCD_ST	P35568	IRS1	Q05655	PRKCD	S795	R790C	790	Missense	distal	-5	no	7.681	7.204	EPSD	COSMIC	7.604	Loss
AGC_PKC_PKCd_PRKCD_ST	P35568	IRS1	Q05655	PRKCD	S795	A801V	801	Missense	distal	6	no	7.681	7.664	EPSD	COSMIC	7.604	Down-regulation
AGC_PKC_PKCd_PRKCD_ST	P35568	IRS1	Q05655	PRKCD	S862	T859M	859	Missense	distal	-3	no	8.316	8.586	EPSD	COSMIC	7.604	Up-regulation
AGC_PKC_PKCd_PRKCD_ST	P35568	IRS1	Q05655	PRKCD	S862	L855P	855	Missense	distal	-7	no	8.316	8.327	EPSD	COSMIC	7.604	Up-regulation
AGC_PKC_PKCd_PRKCD_ST	P35568	IRS1	Q05655	PRKCD	S862	R857Q	857	Missense	distal	-5	no	8.316	7.966	EPSD	COSMIC	7.604	Down-regulation
AGC_PKC_PKCd_PRKCD_ST	P35568	IRS1	Q05655	PRKCD	S862	G864W	864	Missense	proximal	2	no	8.316	7.975	EPSD	COSMIC	7.604	Down-regulation
AGC_PKC_PKCd_PRKCD_ST	P35568	IRS1	Q05655	PRKCD	S862	P858H	858	Missense	distal	-4	no	8.316	8.355	EPSD	COSMIC	7.604	Up-regulation
AGC_PKC_PKCd_PRKCD_ST	P35568	IRS1	Q05655	PRKCD	S869	G864W	864	Missense	distal	-5	no	8.590	8.458	EPSD	COSMIC	7.604	Down-regulation
AGC_PKC_PKCd_PRKCD_ST	P35568	IRS1	Q05655	PRKCD	S869	P872T	872	Missense	distal	3	no	8.590	8.454	EPSD	COSMIC	7.604	Down-regulation
AGC_PKC_PKCd_PRKCD_ST	P35568	IRS1	Q05655	PRKCD	T870	G864W	864	Missense	distal	-6	no	7.797	7.997	EPSD	COSMIC	7.604	Up-regulation
AGC_PKC_PKCd_PRKCD_ST	P35568	IRS1	Q05655	PRKCD	T870	P872T	872	Missense	proximal	2	no	7.797	7.360	EPSD	COSMIC	7.604	Loss
AGC_PKC_PKCd_PRKCD_ST	P35568	IRS1	Q05655	PRKCD	S984	P983S	983	Missense	proximal	-1	no	8.916	8.957	EPSD	COSMIC	7.604	Up-regulation
AGC_PKC_PKCd_PRKCD_ST	P35568	IRS1	Q05655	PRKCD	S984	S985N	985	Missense	proximal	1	no	8.916	8.832	EPSD	COSMIC	7.604	Down-regulation
AGC_PKC_PKCd_PRKCD_ST	P35568	IRS1	Q05655	PRKCD	S995	M992K	992	Missense	distal	-3	no	4.776	8.563	EPSD	COSMIC	7.604	Gain
AGC_PKC_PKCd_PRKCD_ST	P35568	IRS1	Q05655	PRKCD	S1000	R998C	998	Missense	proximal	-2	no	8.052	2.058	EPSD	COSMIC;GDSC;CCLE	7.604	Loss
AGC_PKC_PKCd_PRKCD_ST	P35568	IRS1	Q05655	PRKCD	S1000	D1003H	1003	Missense	distal	3	no	8.052	8.268	EPSD	COSMIC	7.604	Up-regulation
AGC_PKC_PKCd_PRKCD_ST	P35568	IRS1	Q05655	PRKCD	S1000	P997S	997	Missense	distal	-3	no	8.052	7.720	EPSD	COSMIC	7.604	Down-regulation
AGC_PKC_PKCd_PRKCD_ST	P35568	IRS1	Q05655	PRKCD	S1084	P1079S	1079	Missense	distal	-5	no	12.466	12.475	EPSD	COSMIC	7.604	Up-regulation
AGC_PKC_PKCd_PRKCD_ST	P35568	IRS1	Q05655	PRKCD	S1084	S1078I	1078	Missense	distal	-6	no	12.466	12.735	EPSD	COSMIC	7.604	Up-regulation
AGC_PKC_PKCd_PRKCD_ST	P35568	IRS1	Q05655	PRKCD	S1084	V1087A	1087	Missense	distal	3	no	12.466	12.699	EPSD	COSMIC	7.604	Up-regulation
AGC_PKC_PKCd_PRKCD_ST	P35568	IRS1	Q05655	PRKCD	S1084	R1081C	1081	Missense	distal	-3	no	12.466	7.147	EPSD	COSMIC	7.604	Loss
AGC_PKC_PKCd_PRKCD_ST	P35568	IRS1	Q05655	PRKCD	S1100	R1097W	1097	Missense	distal	-3	no	12.851	7.555	EPSD	COSMIC	7.604	Loss
AGC_PKC_PKCd_PRKCD_ST	P35568	IRS1	Q05655	PRKCD	S1100	E1102K	1102	Missense	proximal	2	no	12.851	18.606	EPSD	COSMIC	7.604	Up-regulation
AGC_PKC_PKCd_PRKCD_ST	P35568	IRS1	Q05655	PRKCD	S1101	R1097W	1097	Missense	distal	-4	no	9.221	9.753	EPSD	COSMIC	7.604	Up-regulation
AGC_PKC_PKCd_PRKCD_ST	P35568	IRS1	Q05655	PRKCD	S1101	E1102K	1102	Missense	proximal	1	no	9.221	9.382	EPSD	COSMIC	7.604	Up-regulation
AGC_PKC_PKCd_PRKCD_ST	P35568	IRS1	Q05655	PRKCD	S1142	R1140C	1140	Missense	proximal	-2	no	14.459	8.464	EPSD	COSMIC;CCLE	7.604	Down-regulation
AGC_PKC_PKCd_PRKCD_ST	P35568	IRS1	Q05655	PRKCD	S1143	R1140C	1140	Missense	distal	-3	no	8.725	3.406	EPSD	COSMIC;CCLE	7.604	Loss
AGC_PKC_PKCd_PRKCD_ST	P35568	IRS1	Q05655	PRKCD	S1218	G1212V	1212	Missense	distal	-6	no	11.542	11.593	EPSD	COSMIC	7.604	Up-regulation
AGC_PKC_PKCd_PRKCD_ST	P35568	IRS1	Q05655	PRKCD	S1218	R1220C	1220	Missense	proximal	2	no	11.542	4.663	EPSD	COSMIC	7.604	Loss
AGC_PKC_PKCd_PRKCD_ST	P35568	IRS1	Q05655	PRKCD	S1218	D1225Y	1225	Missense	distal	7	no	11.542	11.511	EPSD	COSMIC	7.604	Down-regulation
AGC_PKC_PKCd_PRKCD_ST	P35568	IRS1	Q05655	PRKCD	S1218	E1224Q	1224	Missense	distal	6	no	11.542	11.548	EPSD	COSMIC	7.604	Up-regulation
AGC_PKC_PKCd_PRKCD_ST	P35568	IRS1	Q05655	PRKCD	T1219	G1212V	1212	Missense	distal	-7	no	8.904	8.902	EPSD	COSMIC	7.604	Down-regulation
AGC_PKC_PKCd_PRKCD_ST	P35568	IRS1	Q05655	PRKCD	T1219	R1220C	1220	Missense	proximal	1	no	8.904	8.691	EPSD	COSMIC	7.604	Down-regulation
AGC_PKC_PKCd_PRKCD_ST	P35568	IRS1	Q05655	PRKCD	T1219	D1225Y	1225	Missense	distal	6	no	8.904	8.884	EPSD	COSMIC	7.604	Down-regulation
AGC_PKC_PKCd_PRKCD_ST	P35568	IRS1	Q05655	PRKCD	T1219	E1224Q	1224	Missense	distal	5	no	8.904	8.947	EPSD	COSMIC	7.604	Up-regulation
AGC_PKC_PKCd_PRKCD_ST	P35568	IRS1	Q05655	PRKCD	T1219	L1226V	1226	Missense	distal	7	no	8.904	8.899	EPSD	COSMIC	7.604	Down-regulation
AGC_PKC_PKCd_PRKCD_ST	P35568	IRS1	Q05655	PRKCD	S1222	R1220C	1220	Missense	proximal	-2	no	8.311	2.317	EPSD	COSMIC	7.604	Loss
AGC_PKC_PKCd_PRKCD_ST	P35568	IRS1	Q05655	PRKCD	S1222	D1225Y	1225	Missense	distal	3	no	8.311	8.080	EPSD	COSMIC	7.604	Down-regulation
AGC_PKC_PKCd_PRKCD_ST	P35568	IRS1	Q05655	PRKCD	S1222	A1228V	1228	Missense	distal	6	no	8.311	8.294	EPSD	COSMIC	7.604	Down-regulation
AGC_PKC_PKCd_PRKCD_ST	P35568	IRS1	Q05655	PRKCD	S1222	E1224Q	1224	Missense	proximal	2	no	8.311	8.454	EPSD	COSMIC	7.604	Up-regulation
AGC_PKC_PKCd_PRKCD_ST	P35568	IRS1	Q05655	PRKCD	S1222	L1226V	1226	Missense	distal	4	no	8.311	8.255	EPSD	COSMIC	7.604	Down-regulation
AGC_PKC_PKCd_PRKCD_ST	P35568	IRS1	Q05655	PRKCD	S1223	R1220C	1220	Missense	distal	-3	no	13.549	8.229	EPSD	COSMIC	7.604	Down-regulation
AGC_PKC_PKCd_PRKCD_ST	P35568	IRS1	Q05655	PRKCD	S1223	D1225Y	1225	Missense	proximal	2	no	13.549	12.472	EPSD	COSMIC	7.604	Down-regulation
AGC_PKC_PKCd_PRKCD_ST	P35568	IRS1	Q05655	PRKCD	S1223	A1228V	1228	Missense	distal	5	no	13.549	13.428	EPSD	COSMIC	7.604	Down-regulation
AGC_PKC_PKCd_PRKCD_ST	P35568	IRS1	Q05655	PRKCD	S1223	E1224Q	1224	Missense	proximal	1	no	13.549	13.562	EPSD	COSMIC	7.604	Up-regulation
AGC_PKC_PKCd_PRKCD_ST	P35568	IRS1	Q05655	PRKCD	S1223	L1226V	1226	Missense	distal	3	no	13.549	13.537	EPSD	COSMIC	7.604	Down-regulation
AGC_PKC_PKCd_PRKCD_ST	Q9NRY6	PLSCR3	Q05655	PRKCD	S230	R235C	235	Missense	distal	5	no	8.291	7.726	EPSD	COSMIC	7.604	Down-regulation
AGC_PKC_PKCd_PRKCD_ST	Q96A00	PPP1R14A	Q05655	PRKCD	T38	V39I	39	Missense	proximal	1	no	11.869	11.861	PhosphoSitePlus	COSMIC;CCLE	7.604	Down-regulation
AGC_PKC_PKCd_PRKCD_ST	Q96A00	PPP1R14A	Q05655	PRKCD	T38	D42N	42	Missense	distal	4	no	11.869	11.844	PhosphoSitePlus	COSMIC	7.604	Down-regulation
AGC_PKC_PKCd_PRKCD_ST	Q96A00	PPP1R14A	Q05655	PRKCD	S128	P122L	122	Missense	distal	-6	no	8.699	8.868	EPSD	COSMIC	7.604	Up-regulation
AGC_PKC_PKCd_PRKCD_ST	P11413	G6PD	Q05655	PRKCD	T76	R81H	81	Missense	distal	5	no	8.054	7.702	EPSD	COSMIC	7.604	Down-regulation
AGC_PKC_PKCd_PRKCD_ST	P11413	G6PD	Q05655	PRKCD	S84	R81H	81	Missense	distal	-3	no	14.867	10.612	EPSD	COSMIC	7.604	Down-regulation
AGC_PKC_PKCd_PRKCD_ST	P11413	G6PD	Q05655	PRKCD	S106	R104H	104	Missense	proximal	-2	no	8.039	3.064	EPSD	COSMIC	7.604	Loss
AGC_PKC_PKCd_PRKCD_ST	P11413	G6PD	Q05655	PRKCD	S106	Y112H	112	Missense	distal	6	no	8.039	8.063	EPSD	COSMIC	7.604	Up-regulation
AGC_PKC_PKCd_PRKCD_ST	P11413	G6PD	Q05655	PRKCD	S123	N126D	126	Missense	distal	3	no	7.632	7.657	EPSD	COSMIC	7.604	Up-regulation
AGC_PKC_PKCd_PRKCD_ST	P11413	G6PD	Q05655	PRKCD	S123	H129P	129	Missense	distal	6	no	7.632	7.644	EPSD	COSMIC	7.604	Up-regulation
AGC_PKC_PKCd_PRKCD_ST	P11413	G6PD	Q05655	PRKCD	S180	R175M	175	Missense	distal	-5	no	9.415	8.985	EPSD	COSMIC	7.604	Down-regulation
AGC_PKC_PKCd_PRKCD_ST	Q00535	CDK5	Q05655	PRKCD	T77	F82I	82	Missense	distal	5	no	8.760	8.638	PhosphoSitePlus	COSMIC	7.604	Down-regulation
AGC_PKC_PKCd_PRKCD_ST	P53671	LIMK2	Q05655	PRKCD	T278	E273K	273	Missense	distal	-5	no	7.629	7.987	EPSD	COSMIC	7.604	Up-regulation
AGC_PKC_PKCd_PRKCD_ST	P53671	LIMK2	Q05655	PRKCD	T278	R282C	282	Missense	distal	4	no	7.629	6.833	EPSD	COSMIC	7.604	Loss
AGC_PKC_PKCd_PRKCD_ST	P53671	LIMK2	Q05655	PRKCD	T278	T278R	278	Missense	central	0	yes	7.629	0.000	EPSD	COSMIC	7.604	Loss
AGC_PKC_PKCd_PRKCD_ST	P53671	LIMK2	Q05655	PRKCD	T278	R280M	280	Missense	proximal	2	no	7.629	1.438	EPSD	COSMIC	7.604	Loss
AGC_PKC_PKCd_PRKCD_ST	P53671	LIMK2	Q05655	PRKCD	T278	E273D	273	Missense	distal	-5	no	7.629	7.631	EPSD	COSMIC	7.604	Up-regulation
AGC_PKC_PKCd_PRKCD_ST	P53671	LIMK2	Q05655	PRKCD	T278	S283F	283	Missense	distal	5	no	7.629	7.418	EPSD	COSMIC	7.604	Loss
AGC_PKC_PKCd_PRKCD_ST	P53671	LIMK2	Q05655	PRKCD	S283	R286C	286	Missense	distal	3	no	19.268	17.994	PhosphoSitePlus	COSMIC	7.604	Down-regulation
AGC_PKC_PKCd_PRKCD_ST	P53671	LIMK2	Q05655	PRKCD	S283	R282C	282	Missense	proximal	-1	no	19.268	19.057	PhosphoSitePlus	COSMIC	7.604	Down-regulation
AGC_PKC_PKCd_PRKCD_ST	P53671	LIMK2	Q05655	PRKCD	S283	R286H	286	Missense	distal	3	no	19.268	18.380	PhosphoSitePlus	COSMIC;CCLE	7.604	Down-regulation
AGC_PKC_PKCd_PRKCD_ST	P53671	LIMK2	Q05655	PRKCD	S283	T278R	278	Missense	distal	-5	no	19.268	19.568	PhosphoSitePlus	COSMIC	7.604	Up-regulation
AGC_PKC_PKCd_PRKCD_ST	P53671	LIMK2	Q05655	PRKCD	S283	R280M	280	Missense	distal	-3	no	19.268	14.445	PhosphoSitePlus	COSMIC	7.604	Down-regulation
AGC_PKC_PKCd_PRKCD_ST	P53671	LIMK2	Q05655	PRKCD	S283	S283F	283	Missense	central	0	yes	19.268	0.000	PhosphoSitePlus	COSMIC	7.604	Loss
AGC_PKC_PKCd_PRKCD_ST	P53671	LIMK2	Q05655	PRKCD	S283	S289R	289	Missense	distal	6	no	19.268	19.301	PhosphoSitePlus	COSMIC	7.604	Up-regulation
AGC_PKC_PKCd_PRKCD_ST	P53671	LIMK2	Q05655	PRKCD	S283	R286Q	286	Missense	distal	3	no	19.268	18.190	PhosphoSitePlus	COSMIC	7.604	Down-regulation
AGC_PKC_PKCd_PRKCD_ST	P53671	LIMK2	Q05655	PRKCD	S287	S283F	283	Missense	distal	-4	no	7.497	7.627	EPSD	COSMIC	7.604	Gain
AGC_PKC_PKCd_PRKCD_ST	P53671	LIMK2	Q05655	PRKCD	S287	S289R	289	Missense	proximal	2	no	7.497	13.560	EPSD	COSMIC	7.604	Gain
AGC_PKC_PKCd_PRKCD_ST	P53671	LIMK2	Q05655	PRKCD	S289	S291F	291	Missense	proximal	2	no	9.537	9.481	EPSD	COSMIC	7.604	Down-regulation
AGC_PKC_PKCd_PRKCD_ST	P53671	LIMK2	Q05655	PRKCD	S289	R286C	286	Missense	distal	-3	no	9.537	4.218	EPSD	COSMIC	7.604	Loss
AGC_PKC_PKCd_PRKCD_ST	P53671	LIMK2	Q05655	PRKCD	S289	R282C	282	Missense	distal	-7	no	9.537	9.512	EPSD	COSMIC	7.604	Down-regulation
AGC_PKC_PKCd_PRKCD_ST	P53671	LIMK2	Q05655	PRKCD	S289	R286H	286	Missense	distal	-3	no	9.537	5.283	EPSD	COSMIC;CCLE	7.604	Loss
AGC_PKC_PKCd_PRKCD_ST	P53671	LIMK2	Q05655	PRKCD	S289	G295D	295	Missense	distal	6	no	9.537	9.543	EPSD	COSMIC	7.604	Up-regulation
AGC_PKC_PKCd_PRKCD_ST	P53671	LIMK2	Q05655	PRKCD	S289	S283F	283	Missense	distal	-6	no	9.537	9.743	EPSD	COSMIC	7.604	Up-regulation
AGC_PKC_PKCd_PRKCD_ST	P53671	LIMK2	Q05655	PRKCD	S289	S289R	289	Missense	central	0	yes	9.537	0.000	EPSD	COSMIC	7.604	Loss
AGC_PKC_PKCd_PRKCD_ST	P53671	LIMK2	Q05655	PRKCD	S289	R286Q	286	Missense	distal	-3	no	9.537	4.380	EPSD	COSMIC	7.604	Loss
AGC_PKC_PKCd_PRKCD_ST	P53671	LIMK2	Q05655	PRKCD	S291	S289R	289	Missense	proximal	-2	no	3.490	8.338	EPSD	COSMIC	7.604	Gain
AGC_PKC_PKCd_PRKCD_ST	P53671	LIMK2	Q05655	PRKCD	S298	S291F	291	Missense	distal	-7	no	8.307	8.297	EPSD	COSMIC	7.604	Down-regulation
AGC_PKC_PKCd_PRKCD_ST	P53671	LIMK2	Q05655	PRKCD	S298	P302L	302	Missense	distal	4	no	8.307	8.103	EPSD	COSMIC;CCLE	7.604	Down-regulation
AGC_PKC_PKCd_PRKCD_ST	P53671	LIMK2	Q05655	PRKCD	S298	G295D	295	Missense	distal	-3	no	8.307	8.476	EPSD	COSMIC	7.604	Up-regulation
AGC_PKC_PKCd_PRKCD_ST	P53671	LIMK2	Q05655	PRKCD	S298	E301Q	301	Missense	distal	3	no	8.307	8.404	EPSD	COSMIC	7.604	Up-regulation
AGC_PKC_PKCd_PRKCD_ST	P53671	LIMK2	Q05655	PRKCD	T494	R493H	493	Missense	proximal	-1	no	16.571	16.426	EPSD	COSMIC	7.604	Down-regulation
AGC_PKC_PKCd_PRKCD_ST	P53671	LIMK2	Q05655	PRKCD	T494	R496H	496	Missense	proximal	2	no	16.571	11.010	EPSD	COSMIC;CCLE	7.604	Down-regulation
AGC_PKC_PKCd_PRKCD_ST	P53671	LIMK2	Q05655	PRKCD	T494	K491N	491	Missense	distal	-3	no	16.571	12.466	EPSD	COSMIC	7.604	Down-regulation
AGC_PKC_PKCd_PRKCD_ST	P53671	LIMK2	Q05655	PRKCD	T505	P510H	510	Missense	distal	5	no	8.530	8.374	EPSD	COSMIC	7.604	Down-regulation
AGC_PKC_PKCd_PRKCD_ST	P53671	LIMK2	Q05655	PRKCD	T505	R503C	503	Missense	proximal	-2	no	8.530	2.535	EPSD	COSMIC	7.604	Loss
AGC_PKC_PKCd_PRKCD_ST	P10588	NR2F6	Q05655	PRKCD	S83	N87K	87	Missense	distal	4	no	15.568	16.213	PhosphoSitePlus	COSMIC	7.604	Up-regulation
AGC_PKC_PKCd_PRKCD_ST	P10588	NR2F6	Q05655	PRKCD	S83	L88F	88	Missense	distal	5	no	15.568	15.547	PhosphoSitePlus	COSMIC;CCLE	7.604	Down-regulation
AGC_PKC_PKCd_PRKCD_ST	P10588	NR2F6	Q05655	PRKCD	S83	S78C	78	Missense	distal	-5	no	15.568	15.366	PhosphoSitePlus	COSMIC	7.604	Down-regulation
AGC_PKC_PKCd_PRKCD_ST	P10588	NR2F6	Q05655	PRKCD	S89	N87K	87	Missense	proximal	-2	no	5.636	10.365	EPSD	COSMIC	7.604	Gain
AGC_PKC_PKCd_PRKCD_ST	P40189	IL6ST	Q05655	PRKCD	S283	T280A	280	Missense	distal	-3	no	7.142	7.895	EPSD	COSMIC	7.604	Gain
AGC_PKC_PKCd_PRKCD_ST	P40189	IL6ST	Q05655	PRKCD	S461	I454T	454	Missense	distal	-7	no	9.153	9.163	EPSD	COSMIC	7.604	Up-regulation
AGC_PKC_PKCd_PRKCD_ST	P40189	IL6ST	Q05655	PRKCD	S461	C466R	466	Missense	distal	5	no	9.153	9.718	EPSD	COSMIC	7.604	Up-regulation
AGC_PKC_PKCd_PRKCD_ST	P40189	IL6ST	Q05655	PRKCD	S782	E781K	781	Missense	proximal	-1	no	7.519	7.693	EPSD	COSMIC	7.604	Gain
AGC_PKC_PKCd_PRKCD_ST	P40189	IL6ST	Q05655	PRKCD	S825	E823K	823	Missense	proximal	-2	no	3.030	8.010	EPSD	COSMIC	7.604	Gain
AGC_PKC_PKCd_PRKCD_ST	Q96D96	HVCN1	Q05655	PRKCD	S97	Q102R	102	Missense	distal	5	no	7.322	7.656	EPSD;PhosphoSitePlus	COSMIC;GDSC	7.604	Gain
AGC_PKC_PKCd_PRKCD_ST	P23396	RPS3	Q05655	PRKCD	S6	A2S	2	Missense	distal	-4	no	9.892	9.809	PhosphoSitePlus;EPSD	COSMIC	7.604	Down-regulation
AGC_PKC_PKCd_PRKCD_ST	P23396	RPS3	Q05655	PRKCD	S104	L110I	110	Missense	distal	6	no	8.374	8.364	EPSD	COSMIC	7.604	Down-regulation
AGC_PKC_PKCd_PRKCD_ST	P23396	RPS3	Q05655	PRKCD	S104	E103D	103	Missense	proximal	-1	no	8.374	8.392	EPSD	COSMIC	7.604	Up-regulation
AGC_PKC_PKCd_PRKCD_ST	P23396	RPS3	Q05655	PRKCD	S104	S104Y	104	Missense	central	0	yes	8.374	0.000	EPSD	COSMIC	7.604	Loss
AGC_PKC_PKCd_PRKCD_ST	P23396	RPS3	Q05655	PRKCD	S104	A100G	100	Missense	distal	-4	no	8.374	8.443	EPSD	COSMIC	7.604	Up-regulation
AGC_PKC_PKCd_PRKCD_ST	P23396	RPS3	Q05655	PRKCD	S104	R106C	106	Missense	proximal	2	no	8.374	1.495	EPSD	COSMIC	7.604	Loss
AGC_PKC_PKCd_PRKCD_ST	P23396	RPS3	Q05655	PRKCD	S104	L105V	105	Missense	proximal	1	no	8.374	8.332	EPSD	COSMIC	7.604	Down-regulation
AGC_PKC_PKCd_PRKCD_ST	P23396	RPS3	Q05655	PRKCD	S139	V138A	138	Missense	proximal	-1	no	7.778	7.828	EPSD	COSMIC	7.604	Up-regulation
AGC_PKC_PKCd_PRKCD_ST	P23396	RPS3	Q05655	PRKCD	S139	K132N	132	Missense	distal	-7	no	7.778	7.753	EPSD	COSMIC	7.604	Down-regulation
AGC_PKC_PKCd_PRKCD_ST	P23396	RPS3	Q05655	PRKCD	S149	K148N	148	Missense	proximal	-1	no	12.233	12.052	EPSD	COSMIC	7.604	Down-regulation
AGC_PKC_PKCd_PRKCD_ST	P23396	RPS3	Q05655	PRKCD	S149	V153L	153	Missense	distal	4	no	12.233	12.288	EPSD	COSMIC	7.604	Up-regulation
AGC_PKC_PKCd_PRKCD_ST	P23396	RPS3	Q05655	PRKCD	S149	K151N	151	Missense	proximal	2	no	12.233	6.859	EPSD	COSMIC	7.604	Loss
AGC_PKC_PKCd_PRKCD_ST	P23396	RPS3	Q05655	PRKCD	S209	H207R	207	Missense	proximal	-2	no	3.006	7.982	EPSD	COSMIC	7.604	Gain
AGC_PKC_PKCd_PRKCD_ST	O14939	PLD2	Q05655	PRKCD	T76	G78R	78	Missense	proximal	2	no	3.226	9.557	EPSD	COSMIC	7.604	Gain
AGC_PKC_PKCd_PRKCD_ST	O14939	PLD2	Q05655	PRKCD	T99	H106D	106	Missense	distal	7	no	8.289	8.270	EPSD	COSMIC	7.604	Down-regulation
AGC_PKC_PKCd_PRKCD_ST	O14939	PLD2	Q05655	PRKCD	T99	R105L	105	Missense	distal	6	no	8.289	8.226	EPSD	COSMIC	7.604	Down-regulation
AGC_PKC_PKCd_PRKCD_ST	O14939	PLD2	Q05655	PRKCD	T99	R105H	105	Missense	distal	6	no	8.289	8.239	EPSD	COSMIC	7.604	Down-regulation
AGC_PKC_PKCd_PRKCD_ST	O14939	PLD2	Q05655	PRKCD	S213	R210Q	210	Missense	distal	-3	no	14.005	8.847	EPSD	COSMIC	7.604	Down-regulation
AGC_PKC_PKCd_PRKCD_ST	O14939	PLD2	Q05655	PRKCD	T274	G279S	279	Missense	distal	5	no	13.611	13.826	EPSD	COSMIC	7.604	Up-regulation
AGC_PKC_PKCd_PRKCD_ST	O14939	PLD2	Q05655	PRKCD	S416	S416I	416	Missense	central	0	yes	7.863	0.000	EPSD	COSMIC	7.604	Loss
AGC_PKC_PKCd_PRKCD_ST	O14939	PLD2	Q05655	PRKCD	S493	P487A	487	Missense	distal	-6	no	9.471	9.512	EPSD	COSMIC	7.604	Up-regulation
AGC_PKC_PKCd_PRKCD_ST	O14939	PLD2	Q05655	PRKCD	S493	R490H	490	Missense	distal	-3	no	9.471	5.216	EPSD	COSMIC;CCLE	7.604	Loss
AGC_PKC_PKCd_PRKCD_ST	O14939	PLD2	Q05655	PRKCD	S814	Q807E	807	Missense	distal	-7	no	10.890	10.886	EPSD	COSMIC	7.604	Down-regulation
AGC_PKC_PKCd_PRKCD_ST	O14939	PLD2	Q05655	PRKCD	S814	L813R	813	Missense	proximal	-1	no	10.890	11.081	EPSD	COSMIC	7.604	Up-regulation
AGC_PKC_PKCd_PRKCD_ST	O14939	PLD2	Q05655	PRKCD	S814	H818R	818	Missense	distal	4	no	10.890	11.433	EPSD	COSMIC	7.604	Up-regulation
AGC_PKC_PKCd_PRKCD_ST	O95817	BAG3	Q05655	PRKCD	S173	R170L	170	Missense	distal	-3	no	8.090	2.904	EPSD	COSMIC	7.604	Loss
AGC_PKC_PKCd_PRKCD_ST	O95817	BAG3	Q05655	PRKCD	S191	R193T	193	Missense	proximal	2	no	9.348	3.093	EPSD	COSMIC	7.604	Loss
AGC_PKC_PKCd_PRKCD_ST	O95817	BAG3	Q05655	PRKCD	S191	P189L	189	Missense	proximal	-2	no	9.348	7.678	EPSD	COSMIC;GDSC;CCLE	7.604	Down-regulation
AGC_PKC_PKCd_PRKCD_ST	O95817	BAG3	Q05655	PRKCD	S264	R261W	261	Missense	distal	-3	no	8.309	3.012	EPSD	COSMIC;CCLE	7.604	Loss
AGC_PKC_PKCd_PRKCD_ST	O95817	BAG3	Q05655	PRKCD	S264	P265L	265	Missense	proximal	1	no	8.309	8.234	EPSD	COSMIC	7.604	Down-regulation
AGC_PKC_PKCd_PRKCD_ST	O95817	BAG3	Q05655	PRKCD	S264	S269F	269	Missense	distal	5	no	8.309	8.098	EPSD	COSMIC	7.604	Down-regulation
AGC_PKC_PKCd_PRKCD_ST	O95817	BAG3	Q05655	PRKCD	S264	R258W	258	Missense	distal	-6	no	8.309	8.901	EPSD	COSMIC	7.604	Up-regulation
AGC_PKC_PKCd_PRKCD_ST	O95817	BAG3	Q05655	PRKCD	S269	S275I	275	Missense	distal	6	no	7.782	7.742	EPSD	COSMIC	7.604	Down-regulation
AGC_PKC_PKCd_PRKCD_ST	O95817	BAG3	Q05655	PRKCD	S269	P265L	265	Missense	distal	-4	no	7.782	7.921	EPSD	COSMIC	7.604	Up-regulation
AGC_PKC_PKCd_PRKCD_ST	O95817	BAG3	Q05655	PRKCD	S269	S269F	269	Missense	central	0	yes	7.782	0.000	EPSD	COSMIC	7.604	Loss
AGC_PKC_PKCd_PRKCD_ST	O95817	BAG3	Q05655	PRKCD	S279	S275I	275	Missense	distal	-4	no	9.528	9.739	EPSD	COSMIC	7.604	Up-regulation
AGC_PKC_PKCd_PRKCD_ST	O95817	BAG3	Q05655	PRKCD	S279	R282K	282	Missense	distal	3	no	9.528	9.535	EPSD	COSMIC	7.604	Up-regulation
AGC_PKC_PKCd_PRKCD_ST	O95817	BAG3	Q05655	PRKCD	S284	R282K	282	Missense	proximal	-2	no	8.686	7.440	EPSD	COSMIC	7.604	Loss
AGC_PKC_PKCd_PRKCD_ST	O95817	BAG3	Q05655	PRKCD	S359	P358S	358	Missense	proximal	-1	no	8.570	8.610	EPSD	COSMIC	7.604	Up-regulation
AGC_PKC_PKCd_PRKCD_ST	O95817	BAG3	Q05655	PRKCD	S359	P356S	356	Missense	distal	-3	no	8.570	8.238	EPSD	COSMIC	7.604	Down-regulation
AGC_PKC_PKCd_PRKCD_ST	P29353	SHC1	Q05655	PRKCD	S80	A74P	74	Missense	distal	-6	no	7.765	7.723	EPSD	COSMIC	7.604	Down-regulation
AGC_PKC_PKCd_PRKCD_ST	P29353	SHC1	Q05655	PRKCD	S80	G75R	75	Missense	distal	-5	no	7.765	8.178	EPSD	COSMIC	7.604	Up-regulation
AGC_PKC_PKCd_PRKCD_ST	P29353	SHC1	Q05655	PRKCD	S139	T135P	135	Missense	distal	-4	no	9.770	9.740	EPSD	COSMIC;GDSC	7.604	Down-regulation
AGC_PKC_PKCd_PRKCD_ST	P29353	SHC1	Q05655	PRKCD	S139	R146W	146	Missense	distal	7	no	9.770	9.605	EPSD	COSMIC	7.604	Down-regulation
AGC_PKC_PKCd_PRKCD_ST	P29353	SHC1	Q05655	PRKCD	T206	R208Q	208	Missense	proximal	2	no	10.677	3.888	EPSD	COSMIC	7.604	Loss
AGC_PKC_PKCd_PRKCD_ST	P29353	SHC1	Q05655	PRKCD	T206	R208W	208	Missense	proximal	2	no	10.677	4.004	EPSD	COSMIC	7.604	Loss
AGC_PKC_PKCd_PRKCD_ST	P29353	SHC1	Q05655	PRKCD	T206	R209K	209	Missense	distal	3	no	10.677	10.684	EPSD	COSMIC	7.604	Up-regulation
AGC_PKC_PKCd_PRKCD_ST	P29353	SHC1	Q05655	PRKCD	T206	G204E	204	Missense	proximal	-2	no	10.677	10.215	EPSD	COSMIC	7.604	Down-regulation
AGC_PKC_PKCd_PRKCD_ST	P29353	SHC1	Q05655	PRKCD	S494	S494R	494	Missense	central	0	yes	12.741	0.000	EPSD	COSMIC	7.604	Loss
AGC_PKC_PKCd_PRKCD_ST	P29353	SHC1	Q05655	PRKCD	S494	P487L	487	Missense	distal	-7	no	12.741	12.730	EPSD	COSMIC	7.604	Down-regulation
AGC_PKC_PKCd_PRKCD_ST	P29353	SHC1	Q05655	PRKCD	S494	F489L	489	Missense	distal	-5	no	12.741	12.695	EPSD	COSMIC	7.604	Down-regulation
AGC_PKC_PKCd_PRKCD_ST	P29353	SHC1	Q05655	PRKCD	S513	R511W	511	Missense	proximal	-2	no	8.418	2.164	EPSD	COSMIC	7.604	Loss
AGC_PKC_PKCd_PRKCD_ST	Q15717	ELAVL1	Q05655	PRKCD	S88	L86H	86	Missense	proximal	-2	no	7.282	8.439	EPSD	COSMIC	7.604	Gain
AGC_PKC_PKCd_PRKCD_ST	Q15717	ELAVL1	Q05655	PRKCD	S94	A96V	96	Missense	proximal	2	no	7.889	6.742	EPSD	COSMIC	7.604	Loss
AGC_PKC_PKCd_PRKCD_ST	Q15717	ELAVL1	Q05655	PRKCD	S94	R97L	97	Missense	distal	3	no	7.889	6.745	EPSD	COSMIC	7.604	Loss
AGC_PKC_PKCd_PRKCD_ST	Q15717	ELAVL1	Q05655	PRKCD	S94	Q87H	87	Missense	distal	-7	no	7.889	7.888	EPSD	COSMIC	7.604	Down-regulation
AGC_PKC_PKCd_PRKCD_ST	Q15717	ELAVL1	Q05655	PRKCD	S99	A96V	96	Missense	distal	-3	no	7.638	7.176	EPSD	COSMIC	7.604	Loss
AGC_PKC_PKCd_PRKCD_ST	Q15717	ELAVL1	Q05655	PRKCD	S99	R97L	97	Missense	proximal	-2	no	7.638	1.505	EPSD	COSMIC	7.604	Loss
AGC_PKC_PKCd_PRKCD_ST	Q15717	ELAVL1	Q05655	PRKCD	S99	E101G	101	Missense	proximal	2	no	7.638	8.238	EPSD	COSMIC	7.604	Up-regulation
AGC_PKC_PKCd_PRKCD_ST	Q15717	ELAVL1	Q05655	PRKCD	S100	A96V	96	Missense	distal	-4	no	7.665	7.750	EPSD	COSMIC	7.604	Up-regulation
AGC_PKC_PKCd_PRKCD_ST	Q15717	ELAVL1	Q05655	PRKCD	S100	R97L	97	Missense	distal	-3	no	7.665	2.478	EPSD	COSMIC	7.604	Loss
AGC_PKC_PKCd_PRKCD_ST	Q15717	ELAVL1	Q05655	PRKCD	S100	E101G	101	Missense	proximal	1	no	7.665	7.607	EPSD	COSMIC	7.604	Down-regulation
AGC_PKC_PKCd_PRKCD_ST	Q15717	ELAVL1	Q05655	PRKCD	S221	V225I	225	Missense	distal	4	no	8.144	8.078	EPSD;PhosphoSitePlus	COSMIC	7.604	Down-regulation
AGC_PKC_PKCd_PRKCD_ST	Q15717	ELAVL1	Q05655	PRKCD	S318	H325Y	325	Missense	distal	7	no	9.303	9.252	PhosphoSitePlus;EPSD	COSMIC	7.604	Down-regulation
AGC_PKC_PKCd_PRKCD_ST	Q15717	ELAVL1	Q05655	PRKCD	S318	K323R	323	Missense	distal	5	no	9.303	9.241	PhosphoSitePlus;EPSD	COSMIC	7.604	Down-regulation
AGC_PKC_PKCd_PRKCD_ST	O00165	HAX1	Q05655	PRKCD	S153	S151R	151	Missense	proximal	-2	no	6.101	10.949	EPSD	COSMIC	7.604	Gain
AGC_PKC_PKCd_PRKCD_ST	O00165	HAX1	Q05655	PRKCD	S255	R250Q	250	Missense	distal	-5	no	11.418	11.067	EPSD	COSMIC	7.604	Down-regulation
AGC_PKC_PKCd_PRKCD_ST	O00165	HAX1	Q05655	PRKCD	S255	R257I	257	Missense	proximal	2	no	11.418	4.423	EPSD	COSMIC;GDSC;CCLE	7.604	Loss
AGC_PKC_PKCd_PRKCD_ST	P35222	CTNNB1	Q05655	PRKCD	S23	W25R	25	Missense	proximal	2	no	3.892	10.565	EPSD	COSMIC	7.604	Gain
AGC_PKC_PKCd_PRKCD_ST	P35222	CTNNB1	Q05655	PRKCD	S37	I35K	35	Missense	proximal	-2	no	4.243	9.722	EPSD	COSMIC	7.604	Gain
AGC_PKC_PKCd_PRKCD_ST	P35222	CTNNB1	Q05655	PRKCD	S45	T42R	42	Missense	distal	-3	no	3.044	8.136	EPSD	COSMIC	7.604	Gain
AGC_PKC_PKCd_PRKCD_ST	P35222	CTNNB1	Q05655	PRKCD	S45	S47R	47	Missense	proximal	2	no	3.044	9.107	EPSD	COSMIC	7.604	Gain
AGC_PKC_PKCd_PRKCD_ST	P35222	CTNNB1	Q05655	PRKCD	S47	S45T	45	Missense	proximal	-2	no	7.734	6.620	EPSD	COSMIC	7.604	Loss
AGC_PKC_PKCd_PRKCD_ST	P35222	CTNNB1	Q05655	PRKCD	S47	P44S	44	Missense	distal	-3	no	7.734	7.402	EPSD	COSMIC	7.604	Loss
AGC_PKC_PKCd_PRKCD_ST	P35222	CTNNB1	Q05655	PRKCD	S47	A43V	43	Missense	distal	-4	no	7.734	7.819	EPSD	COSMIC	7.604	Up-regulation
AGC_PKC_PKCd_PRKCD_ST	P35222	CTNNB1	Q05655	PRKCD	S47	G48D	48	Missense	proximal	1	no	7.734	7.764	EPSD	COSMIC	7.604	Up-regulation
AGC_PKC_PKCd_PRKCD_ST	P35222	CTNNB1	Q05655	PRKCD	S47	N51T	51	Missense	distal	4	no	7.734	7.882	EPSD	COSMIC	7.604	Up-regulation
AGC_PKC_PKCd_PRKCD_ST	P35222	CTNNB1	Q05655	PRKCD	S47	P52L	52	Missense	distal	5	no	7.734	7.512	EPSD	COSMIC	7.604	Loss
AGC_PKC_PKCd_PRKCD_ST	P35222	CTNNB1	Q05655	PRKCD	S47	E53K	53	Missense	distal	6	no	7.734	7.789	EPSD	COSMIC	7.604	Up-regulation
AGC_PKC_PKCd_PRKCD_ST	P35222	CTNNB1	Q05655	PRKCD	S47	N51S	51	Missense	distal	4	no	7.734	7.918	EPSD	COSMIC	7.604	Up-regulation
AGC_PKC_PKCd_PRKCD_ST	P35222	CTNNB1	Q05655	PRKCD	S47	T40I	40	Missense	distal	-7	no	7.734	7.724	EPSD	COSMIC	7.604	Down-regulation
AGC_PKC_PKCd_PRKCD_ST	P35222	CTNNB1	Q05655	PRKCD	S47	P44A	44	Missense	distal	-3	no	7.734	7.638	EPSD	COSMIC	7.604	Down-regulation
AGC_PKC_PKCd_PRKCD_ST	P35222	CTNNB1	Q05655	PRKCD	S47	T41P	41	Missense	distal	-6	no	7.734	7.770	EPSD	COSMIC	7.604	Up-regulation
AGC_PKC_PKCd_PRKCD_ST	P35222	CTNNB1	Q05655	PRKCD	S47	E54K	54	Missense	distal	7	no	7.734	7.872	EPSD	COSMIC	7.604	Up-regulation
AGC_PKC_PKCd_PRKCD_ST	P35222	CTNNB1	Q05655	PRKCD	S47	K49R	49	Missense	proximal	2	no	7.734	8.911	EPSD	COSMIC	7.604	Up-regulation
AGC_PKC_PKCd_PRKCD_ST	P35222	CTNNB1	Q05655	PRKCD	S47	T42R	42	Missense	distal	-5	no	7.734	8.034	EPSD	COSMIC	7.604	Up-regulation
AGC_PKC_PKCd_PRKCD_ST	P35222	CTNNB1	Q05655	PRKCD	S47	S45A	45	Missense	proximal	-2	no	7.734	7.772	EPSD	COSMIC	7.604	Up-regulation
AGC_PKC_PKCd_PRKCD_ST	P35222	CTNNB1	Q05655	PRKCD	S47	G48S	48	Missense	proximal	1	no	7.734	7.841	EPSD	COSMIC	7.604	Up-regulation
AGC_PKC_PKCd_PRKCD_ST	P35222	CTNNB1	Q05655	PRKCD	S47	T40A	40	Missense	distal	-7	no	7.734	7.733	EPSD	COSMIC	7.604	Down-regulation
AGC_PKC_PKCd_PRKCD_ST	P35222	CTNNB1	Q05655	PRKCD	S47	A43T	43	Missense	distal	-4	no	7.734	7.704	EPSD	COSMIC	7.604	Down-regulation
AGC_PKC_PKCd_PRKCD_ST	P35222	CTNNB1	Q05655	PRKCD	S47	P44L	44	Missense	distal	-3	no	7.734	6.791	EPSD	COSMIC	7.604	Loss
AGC_PKC_PKCd_PRKCD_ST	P35222	CTNNB1	Q05655	PRKCD	S47	T42I	42	Missense	distal	-5	no	7.734	7.567	EPSD	COSMIC	7.604	Loss
AGC_PKC_PKCd_PRKCD_ST	P35222	CTNNB1	Q05655	PRKCD	S47	T42S	42	Missense	distal	-5	no	7.734	7.759	EPSD	COSMIC	7.604	Up-regulation
AGC_PKC_PKCd_PRKCD_ST	P35222	CTNNB1	Q05655	PRKCD	S47	T42K	42	Missense	distal	-5	no	7.734	8.008	EPSD	COSMIC	7.604	Up-regulation
AGC_PKC_PKCd_PRKCD_ST	P35222	CTNNB1	Q05655	PRKCD	S47	S47G	47	Missense	central	0	yes	7.734	0.000	EPSD	COSMIC	7.604	Loss
AGC_PKC_PKCd_PRKCD_ST	P35222	CTNNB1	Q05655	PRKCD	S47	G48V	48	Missense	proximal	1	no	7.734	7.745	EPSD	COSMIC	7.604	Up-regulation
AGC_PKC_PKCd_PRKCD_ST	P35222	CTNNB1	Q05655	PRKCD	S47	S47N	47	Missense	central	0	yes	7.734	0.000	EPSD	COSMIC	7.604	Loss
AGC_PKC_PKCd_PRKCD_ST	P35222	CTNNB1	Q05655	PRKCD	S47	K49T	49	Missense	proximal	2	no	7.734	2.656	EPSD	COSMIC	7.604	Loss
AGC_PKC_PKCd_PRKCD_ST	P35222	CTNNB1	Q05655	PRKCD	S47	G50D	50	Missense	distal	3	no	7.734	7.768	EPSD	COSMIC	7.604	Up-regulation
AGC_PKC_PKCd_PRKCD_ST	P35222	CTNNB1	Q05655	PRKCD	S47	A43P	43	Missense	distal	-4	no	7.734	7.673	EPSD	COSMIC	7.604	Down-regulation
AGC_PKC_PKCd_PRKCD_ST	P35222	CTNNB1	Q05655	PRKCD	S47	L46P	46	Missense	proximal	-1	no	7.734	7.810	EPSD	COSMIC	7.604	Up-regulation
AGC_PKC_PKCd_PRKCD_ST	P35222	CTNNB1	Q05655	PRKCD	S47	T42A	42	Missense	distal	-5	no	7.734	7.691	EPSD	COSMIC	7.604	Down-regulation
AGC_PKC_PKCd_PRKCD_ST	P35222	CTNNB1	Q05655	PRKCD	S47	L46V	46	Missense	proximal	-1	no	7.734	7.724	EPSD	COSMIC	7.604	Down-regulation
AGC_PKC_PKCd_PRKCD_ST	P35222	CTNNB1	Q05655	PRKCD	S47	S47L	47	Missense	central	0	yes	7.734	0.000	EPSD	COSMIC	7.604	Loss
AGC_PKC_PKCd_PRKCD_ST	P35222	CTNNB1	Q05655	PRKCD	S47	T40S	40	Missense	distal	-7	no	7.734	7.739	EPSD	COSMIC	7.604	Up-regulation
AGC_PKC_PKCd_PRKCD_ST	P35222	CTNNB1	Q05655	PRKCD	S47	K49L	49	Missense	proximal	2	no	7.734	2.034	EPSD	COSMIC	7.604	Loss
AGC_PKC_PKCd_PRKCD_ST	P35222	CTNNB1	Q05655	PRKCD	S47	L46M	46	Missense	proximal	-1	no	7.734	7.730	EPSD	COSMIC	7.604	Down-regulation
AGC_PKC_PKCd_PRKCD_ST	P35222	CTNNB1	Q05655	PRKCD	S47	T41S	41	Missense	distal	-6	no	7.734	7.693	EPSD	COSMIC	7.604	Down-regulation
AGC_PKC_PKCd_PRKCD_ST	P35222	CTNNB1	Q05655	PRKCD	S47	T42Q	42	Missense	distal	-5	no	7.734	7.683	EPSD	COSMIC	7.604	Down-regulation
AGC_PKC_PKCd_PRKCD_ST	P35222	CTNNB1	Q05655	PRKCD	S47	S47C	47	Missense	central	0	yes	7.734	0.000	EPSD	COSMIC	7.604	Loss
AGC_PKC_PKCd_PRKCD_ST	P35222	CTNNB1	Q05655	PRKCD	S47	K49E	49	Missense	proximal	2	no	7.734	1.979	EPSD	COSMIC	7.604	Loss
AGC_PKC_PKCd_PRKCD_ST	P35222	CTNNB1	Q05655	PRKCD	S47	S47R	47	Missense	central	0	yes	7.734	0.000	EPSD	COSMIC	7.604	Loss
AGC_PKC_PKCd_PRKCD_ST	P35222	CTNNB1	Q05655	PRKCD	S47	S45E	45	Missense	proximal	-2	no	7.734	6.357	EPSD	COSMIC	7.604	Loss
AGC_PKC_PKCd_PRKCD_ST	P35222	CTNNB1	Q05655	PRKCD	S47	G50S	50	Missense	distal	3	no	7.734	8.014	EPSD	COSMIC	7.604	Up-regulation
AGC_PKC_PKCd_PRKCD_ST	P35222	CTNNB1	Q05655	PRKCD	S47	S45N	45	Missense	proximal	-2	no	7.734	6.608	EPSD	COSMIC	7.604	Loss
AGC_PKC_PKCd_PRKCD_ST	P35222	CTNNB1	Q05655	PRKCD	S47	L46Q	46	Missense	proximal	-1	no	7.734	7.789	EPSD	COSMIC	7.604	Up-regulation
AGC_PKC_PKCd_PRKCD_ST	P35222	CTNNB1	Q05655	PRKCD	S47	S45X	45	Missense	proximal	-2	no	7.734	6.668	EPSD	COSMIC	7.604	Loss
AGC_PKC_PKCd_PRKCD_ST	P35222	CTNNB1	Q05655	PRKCD	S47	P44I	44	Missense	distal	-3	no	7.734	6.336	EPSD	COSMIC	7.604	Loss
AGC_PKC_PKCd_PRKCD_ST	P35222	CTNNB1	Q05655	PRKCD	S47	S47I	47	Missense	central	0	yes	7.734	0.000	EPSD	COSMIC	7.604	Loss
AGC_PKC_PKCd_PRKCD_ST	P35222	CTNNB1	Q05655	PRKCD	S47	S47Y	47	Missense	central	0	yes	7.734	0.000	EPSD	COSMIC	7.604	Loss
AGC_PKC_PKCd_PRKCD_ST	P35222	CTNNB1	Q05655	PRKCD	S47	T40P	40	Missense	distal	-7	no	7.734	7.738	EPSD	COSMIC	7.604	Up-regulation
AGC_PKC_PKCd_PRKCD_ST	P35222	CTNNB1	Q05655	PRKCD	S179	H176R	176	Missense	distal	-3	no	8.737	12.992	EPSD	COSMIC	7.604	Up-regulation
AGC_PKC_PKCd_PRKCD_ST	P35222	CTNNB1	Q05655	PRKCD	S179	A183S	183	Missense	distal	4	no	8.737	8.804	EPSD	COSMIC	7.604	Up-regulation
AGC_PKC_PKCd_PRKCD_ST	P35222	CTNNB1	Q05655	PRKCD	S179	Q177P	177	Missense	proximal	-2	no	8.737	9.708	EPSD	COSMIC	7.604	Up-regulation
AGC_PKC_PKCd_PRKCD_ST	P35222	CTNNB1	Q05655	PRKCD	S179	V175I	175	Missense	distal	-4	no	8.737	8.780	EPSD	COSMIC	7.604	Up-regulation
AGC_PKC_PKCd_PRKCD_ST	P35222	CTNNB1	Q05655	PRKCD	S179	A183T	183	Missense	distal	4	no	8.737	8.769	EPSD	COSMIC	7.604	Up-regulation
AGC_PKC_PKCd_PRKCD_ST	P35222	CTNNB1	Q05655	PRKCD	S179	E182D	182	Missense	distal	3	no	8.737	8.808	EPSD	COSMIC	7.604	Up-regulation
AGC_PKC_PKCd_PRKCD_ST	P35222	CTNNB1	Q05655	PRKCD	S179	R185K	185	Missense	distal	6	no	8.737	8.739	EPSD	COSMIC	7.604	Up-regulation
AGC_PKC_PKCd_PRKCD_ST	P35222	CTNNB1	Q05655	PRKCD	T472	E479K	479	Missense	distal	7	no	11.443	11.580	EPSD	COSMIC	7.604	Up-regulation
AGC_PKC_PKCd_PRKCD_ST	P35222	CTNNB1	Q05655	PRKCD	T472	L468V	468	Missense	distal	-4	no	11.443	11.450	EPSD	COSMIC	7.604	Up-regulation
AGC_PKC_PKCd_PRKCD_ST	P35222	CTNNB1	Q05655	PRKCD	T472	A478T	478	Missense	distal	6	no	11.443	11.454	EPSD	COSMIC	7.604	Up-regulation
AGC_PKC_PKCd_PRKCD_ST	P35222	CTNNB1	Q05655	PRKCD	T472	H475Q	475	Missense	distal	3	no	11.443	11.253	EPSD	COSMIC	7.604	Down-regulation
AGC_PKC_PKCd_PRKCD_ST	P35222	CTNNB1	Q05655	PRKCD	T472	L471Q	471	Missense	proximal	-1	no	11.443	11.497	EPSD	COSMIC	7.604	Up-regulation
AGC_PKC_PKCd_PRKCD_ST	P35222	CTNNB1	Q05655	PRKCD	T472	R469C	469	Missense	distal	-3	no	11.443	6.123	EPSD	COSMIC	7.604	Loss
AGC_PKC_PKCd_PRKCD_ST	P35222	CTNNB1	Q05655	PRKCD	T472	A478G	478	Missense	distal	6	no	11.443	11.435	EPSD	COSMIC	7.604	Down-regulation
AGC_PKC_PKCd_PRKCD_ST	P35222	CTNNB1	Q05655	PRKCD	T547	T551K	551	Missense	distal	4	no	10.676	11.173	EPSD	COSMIC	7.604	Up-regulation
AGC_PKC_PKCd_PRKCD_ST	P35222	CTNNB1	Q05655	PRKCD	T547	R549C	549	Missense	proximal	2	no	10.676	3.797	EPSD	COSMIC	7.604	Loss
AGC_PKC_PKCd_PRKCD_ST	P35222	CTNNB1	Q05655	PRKCD	T547	Q545K	545	Missense	proximal	-2	no	10.676	14.865	EPSD	COSMIC	7.604	Up-regulation
AGC_PKC_PKCd_PRKCD_ST	P35222	CTNNB1	Q05655	PRKCD	T547	A543T	543	Missense	distal	-4	no	10.676	10.645	EPSD	COSMIC	7.604	Down-regulation
AGC_PKC_PKCd_PRKCD_ST	P35222	CTNNB1	Q05655	PRKCD	T547	R550H	550	Missense	distal	3	no	10.676	9.788	EPSD	COSMIC	7.604	Down-regulation
AGC_PKC_PKCd_PRKCD_ST	P35222	CTNNB1	Q05655	PRKCD	T547	L540F	540	Missense	distal	-7	no	10.676	10.677	EPSD	COSMIC	7.604	Up-regulation
AGC_PKC_PKCd_PRKCD_ST	P35222	CTNNB1	Q05655	PRKCD	T547	R550L	550	Missense	distal	3	no	10.676	9.532	EPSD	COSMIC	7.604	Down-regulation
AGC_PKC_PKCd_PRKCD_ST	P35222	CTNNB1	Q05655	PRKCD	T547	A543V	543	Missense	distal	-4	no	10.676	10.761	EPSD	COSMIC	7.604	Up-regulation
AGC_PKC_PKCd_PRKCD_ST	P35222	CTNNB1	Q05655	PRKCD	T547	D546E	546	Missense	proximal	-1	no	10.676	10.657	EPSD	COSMIC	7.604	Down-regulation
AGC_PKC_PKCd_PRKCD_ST	P35222	CTNNB1	Q05655	PRKCD	T547	S552F	552	Missense	distal	5	no	10.676	10.465	EPSD	COSMIC	7.604	Down-regulation
AGC_PKC_PKCd_PRKCD_ST	P35222	CTNNB1	Q05655	PRKCD	T547	G554D	554	Missense	distal	7	no	10.676	10.679	EPSD	COSMIC	7.604	Up-regulation
AGC_PKC_PKCd_PRKCD_ST	P35222	CTNNB1	Q05655	PRKCD	T547	R550Q	550	Missense	distal	3	no	10.676	9.598	EPSD	COSMIC	7.604	Down-regulation
AGC_PKC_PKCd_PRKCD_ST	P35222	CTNNB1	Q05655	PRKCD	T547	T551I	551	Missense	distal	4	no	10.676	10.424	EPSD	COSMIC	7.604	Down-regulation
AGC_PKC_PKCd_PRKCD_ST	P35222	CTNNB1	Q05655	PRKCD	S552	T551K	551	Missense	proximal	-1	no	13.381	13.511	EPSD	COSMIC	7.604	Up-regulation
AGC_PKC_PKCd_PRKCD_ST	P35222	CTNNB1	Q05655	PRKCD	S552	R549C	549	Missense	distal	-3	no	13.381	8.062	EPSD	COSMIC	7.604	Down-regulation
AGC_PKC_PKCd_PRKCD_ST	P35222	CTNNB1	Q05655	PRKCD	S552	Q545K	545	Missense	distal	-7	no	13.381	13.400	EPSD	COSMIC	7.604	Up-regulation
AGC_PKC_PKCd_PRKCD_ST	P35222	CTNNB1	Q05655	PRKCD	S552	Q558H	558	Missense	distal	6	no	13.381	13.378	EPSD	COSMIC	7.604	Down-regulation
AGC_PKC_PKCd_PRKCD_ST	P35222	CTNNB1	Q05655	PRKCD	S552	G555A	555	Missense	distal	3	no	13.381	13.596	EPSD	COSMIC	7.604	Up-regulation
AGC_PKC_PKCd_PRKCD_ST	P35222	CTNNB1	Q05655	PRKCD	S552	R550H	550	Missense	proximal	-2	no	13.381	8.406	EPSD	COSMIC	7.604	Down-regulation
AGC_PKC_PKCd_PRKCD_ST	P35222	CTNNB1	Q05655	PRKCD	S552	R550L	550	Missense	proximal	-2	no	13.381	7.249	EPSD	COSMIC	7.604	Loss
AGC_PKC_PKCd_PRKCD_ST	P35222	CTNNB1	Q05655	PRKCD	S552	D546E	546	Missense	distal	-6	no	13.381	13.396	EPSD	COSMIC	7.604	Up-regulation
AGC_PKC_PKCd_PRKCD_ST	P35222	CTNNB1	Q05655	PRKCD	S552	S552F	552	Missense	central	0	yes	13.381	0.000	EPSD	COSMIC	7.604	Loss
AGC_PKC_PKCd_PRKCD_ST	P35222	CTNNB1	Q05655	PRKCD	S552	T547S	547	Missense	distal	-5	no	13.381	13.407	EPSD	COSMIC	7.604	Up-regulation
AGC_PKC_PKCd_PRKCD_ST	P35222	CTNNB1	Q05655	PRKCD	S552	G554D	554	Missense	proximal	2	no	13.381	13.248	EPSD	COSMIC	7.604	Down-regulation
AGC_PKC_PKCd_PRKCD_ST	P35222	CTNNB1	Q05655	PRKCD	S552	R550Q	550	Missense	proximal	-2	no	13.381	7.947	EPSD	COSMIC	7.604	Down-regulation
AGC_PKC_PKCd_PRKCD_ST	P35222	CTNNB1	Q05655	PRKCD	S552	T551I	551	Missense	proximal	-1	no	13.381	13.292	EPSD	COSMIC	7.604	Down-regulation
AGC_PKC_PKCd_PRKCD_ST	P35222	CTNNB1	Q05655	PRKCD	S675	R673W	673	Missense	proximal	-2	no	11.304	5.050	EPSD	COSMIC	7.604	Loss
AGC_PKC_PKCd_PRKCD_ST	P35222	CTNNB1	Q05655	PRKCD	S675	S680I	680	Missense	distal	5	no	11.304	10.970	EPSD	COSMIC	7.604	Down-regulation
AGC_PKC_PKCd_PRKCD_ST	P35222	CTNNB1	Q05655	PRKCD	S675	E677D	677	Missense	proximal	2	no	11.304	11.770	EPSD	COSMIC	7.604	Up-regulation
AGC_PKC_PKCd_PRKCD_ST	P35222	CTNNB1	Q05655	PRKCD	S675	R673H	673	Missense	proximal	-2	no	11.304	6.328	EPSD	COSMIC	7.604	Loss
AGC_PKC_PKCd_PRKCD_ST	P35222	CTNNB1	Q05655	PRKCD	S675	L678F	678	Missense	distal	3	no	11.304	11.372	EPSD	COSMIC	7.604	Up-regulation
AGC_PKC_PKCd_PRKCD_ST	P35222	CTNNB1	Q05655	PRKCD	S675	R673C	673	Missense	proximal	-2	no	11.304	5.309	EPSD	COSMIC	7.604	Loss
AGC_PKC_PKCd_PRKCD_ST	P35222	CTNNB1	Q05655	PRKCD	S715	Y716C	716	Missense	proximal	1	no	10.409	10.407	PhosphoSitePlus	COSMIC	7.604	Down-regulation
AGC_PKC_PKCd_PRKCD_ST	P35222	CTNNB1	Q05655	PRKCD	S715	H720P	720	Missense	distal	5	no	10.409	10.565	PhosphoSitePlus	COSMIC	7.604	Up-regulation
AGC_PKC_PKCd_PRKCD_ST	P35222	CTNNB1	Q05655	PRKCD	S715	R717C	717	Missense	proximal	2	no	10.409	3.530	PhosphoSitePlus	COSMIC	7.604	Loss
AGC_PKC_PKCd_PRKCD_ST	P35222	CTNNB1	Q05655	PRKCD	S715	S715R	715	Missense	central	0	yes	10.409	0.000	PhosphoSitePlus	COSMIC	7.604	Loss
AGC_PKC_PKCd_PRKCD_ST	P35222	CTNNB1	Q05655	PRKCD	S715	D712N	712	Missense	distal	-3	no	10.409	10.309	PhosphoSitePlus	COSMIC	7.604	Down-regulation
AGC_PKC_PKCd_PRKCD_ST	P35222	CTNNB1	Q05655	PRKCD	S715	P714S	714	Missense	proximal	-1	no	10.409	10.449	PhosphoSitePlus	COSMIC	7.604	Up-regulation
AGC_PKC_PKCd_PRKCD_ST	P35222	CTNNB1	Q05655	PRKCD	S715	Y709C	709	Missense	distal	-6	no	10.409	10.411	PhosphoSitePlus	COSMIC	7.604	Up-regulation
AGC_PKC_PKCd_PRKCD_ST	P35222	CTNNB1	Q05655	PRKCD	S715	R710C	710	Missense	distal	-5	no	10.409	9.932	PhosphoSitePlus	COSMIC	7.604	Down-regulation
AGC_PKC_PKCd_PRKCD_ST	P61073	CXCR4	Q05655	PRKCD	S23	E26K	26	Missense	distal	3	no	7.401	8.582	EPSD	COSMIC	7.604	Gain
AGC_PKC_PKCd_PRKCD_ST	P61073	CXCR4	Q05655	PRKCD	S23	Y21C	21	Missense	proximal	-2	no	7.401	8.247	EPSD	COSMIC	7.604	Gain
AGC_PKC_PKCd_PRKCD_ST	P61073	CXCR4	Q05655	PRKCD	S324	S325R	325	Missense	proximal	1	no	9.089	9.184	PhosphoSitePlus;EPSD	COSMIC	7.604	Up-regulation
AGC_PKC_PKCd_PRKCD_ST	P61073	CXCR4	Q05655	PRKCD	S324	L317I	317	Missense	distal	-7	no	9.089	9.086	PhosphoSitePlus;EPSD	COSMIC	7.604	Down-regulation
AGC_PKC_PKCd_PRKCD_ST	P61073	CXCR4	Q05655	PRKCD	S324	T318A	318	Missense	distal	-6	no	9.089	9.167	PhosphoSitePlus;EPSD	COSMIC	7.604	Up-regulation
AGC_PKC_PKCd_PRKCD_ST	P61073	CXCR4	Q05655	PRKCD	S324	S319F	319	Missense	distal	-5	no	9.089	8.980	PhosphoSitePlus;EPSD	COSMIC	7.604	Down-regulation
AGC_PKC_PKCd_PRKCD_ST	P61073	CXCR4	Q05655	PRKCD	S324	S330Y	330	Missense	distal	6	no	9.089	9.049	PhosphoSitePlus;EPSD	COSMIC	7.604	Down-regulation
AGC_PKC_PKCd_PRKCD_ST	P61073	CXCR4	Q05655	PRKCD	S324	S324F	324	Missense	central	0	yes	9.089	0.000	PhosphoSitePlus;EPSD	COSMIC	7.604	Loss
AGC_PKC_PKCd_PRKCD_ST	P61073	CXCR4	Q05655	PRKCD	S324	L329I	329	Missense	distal	5	no	9.089	8.946	PhosphoSitePlus;EPSD	COSMIC	7.604	Down-regulation
AGC_PKC_PKCd_PRKCD_ST	P61073	CXCR4	Q05655	PRKCD	S324	S330C	330	Missense	distal	6	no	9.089	9.047	PhosphoSitePlus;EPSD	COSMIC	7.604	Down-regulation
AGC_PKC_PKCd_PRKCD_ST	P61073	CXCR4	Q05655	PRKCD	S324	G323W	323	Missense	proximal	-1	no	9.089	8.995	PhosphoSitePlus;EPSD	COSMIC;CCLE	7.604	Down-regulation
AGC_PKC_PKCd_PRKCD_ST	P61073	CXCR4	Q05655	PRKCD	S324	L326P	326	Missense	proximal	2	no	9.089	10.149	PhosphoSitePlus;EPSD	COSMIC	7.604	Up-regulation
AGC_PKC_PKCd_PRKCD_ST	P61073	CXCR4	Q05655	PRKCD	S325	S325R	325	Missense	central	0	yes	12.957	0.000	EPSD;PhosphoSitePlus	COSMIC	7.604	Loss
AGC_PKC_PKCd_PRKCD_ST	P61073	CXCR4	Q05655	PRKCD	S325	T318A	318	Missense	distal	-7	no	12.957	12.955	EPSD;PhosphoSitePlus	COSMIC	7.604	Down-regulation
AGC_PKC_PKCd_PRKCD_ST	P61073	CXCR4	Q05655	PRKCD	S325	S319F	319	Missense	distal	-6	no	12.957	13.162	EPSD;PhosphoSitePlus	COSMIC	7.604	Up-regulation
AGC_PKC_PKCd_PRKCD_ST	P61073	CXCR4	Q05655	PRKCD	S325	G332R	332	Missense	distal	7	no	12.957	13.065	EPSD;PhosphoSitePlus	COSMIC	7.604	Up-regulation
AGC_PKC_PKCd_PRKCD_ST	P61073	CXCR4	Q05655	PRKCD	S325	S330Y	330	Missense	distal	5	no	12.957	12.618	EPSD;PhosphoSitePlus	COSMIC	7.604	Down-regulation
AGC_PKC_PKCd_PRKCD_ST	P61073	CXCR4	Q05655	PRKCD	S325	S324F	324	Missense	proximal	-1	no	12.957	12.850	EPSD;PhosphoSitePlus	COSMIC	7.604	Down-regulation
AGC_PKC_PKCd_PRKCD_ST	P61073	CXCR4	Q05655	PRKCD	S325	L329I	329	Missense	distal	4	no	12.957	12.835	EPSD;PhosphoSitePlus	COSMIC	7.604	Down-regulation
AGC_PKC_PKCd_PRKCD_ST	P61073	CXCR4	Q05655	PRKCD	S325	S330C	330	Missense	distal	5	no	12.957	12.620	EPSD;PhosphoSitePlus	COSMIC	7.604	Down-regulation
AGC_PKC_PKCd_PRKCD_ST	P61073	CXCR4	Q05655	PRKCD	S325	G323W	323	Missense	proximal	-2	no	12.957	12.466	EPSD;PhosphoSitePlus	COSMIC;CCLE	7.604	Down-regulation
AGC_PKC_PKCd_PRKCD_ST	P61073	CXCR4	Q05655	PRKCD	S325	L326P	326	Missense	proximal	1	no	12.957	13.031	EPSD;PhosphoSitePlus	COSMIC	7.604	Up-regulation
AGC_PKC_PKCd_PRKCD_ST	P61073	CXCR4	Q05655	PRKCD	S330	S325R	325	Missense	distal	-5	no	8.413	8.687	EPSD	COSMIC	7.604	Up-regulation
AGC_PKC_PKCd_PRKCD_ST	P61073	CXCR4	Q05655	PRKCD	S330	G335C	335	Missense	distal	5	no	8.413	8.291	EPSD	COSMIC	7.604	Down-regulation
AGC_PKC_PKCd_PRKCD_ST	P61073	CXCR4	Q05655	PRKCD	S330	G332R	332	Missense	proximal	2	no	8.413	14.744	EPSD	COSMIC	7.604	Up-regulation
AGC_PKC_PKCd_PRKCD_ST	P61073	CXCR4	Q05655	PRKCD	S330	G332E	332	Missense	proximal	2	no	8.413	7.812	EPSD	COSMIC	7.604	Down-regulation
AGC_PKC_PKCd_PRKCD_ST	P61073	CXCR4	Q05655	PRKCD	S330	S330Y	330	Missense	central	0	yes	8.413	0.000	EPSD	COSMIC	7.604	Loss
AGC_PKC_PKCd_PRKCD_ST	P61073	CXCR4	Q05655	PRKCD	S330	G336R	336	Missense	distal	6	no	8.413	8.472	EPSD	COSMIC	7.604	Up-regulation
AGC_PKC_PKCd_PRKCD_ST	P61073	CXCR4	Q05655	PRKCD	S330	S324F	324	Missense	distal	-6	no	8.413	8.618	EPSD	COSMIC	7.604	Up-regulation
AGC_PKC_PKCd_PRKCD_ST	P61073	CXCR4	Q05655	PRKCD	S330	L329I	329	Missense	proximal	-1	no	8.413	8.378	EPSD	COSMIC	7.604	Down-regulation
AGC_PKC_PKCd_PRKCD_ST	P61073	CXCR4	Q05655	PRKCD	S330	S330C	330	Missense	central	0	yes	8.413	0.000	EPSD	COSMIC	7.604	Loss
AGC_PKC_PKCd_PRKCD_ST	P61073	CXCR4	Q05655	PRKCD	S330	G323W	323	Missense	distal	-7	no	8.413	8.401	EPSD	COSMIC;CCLE	7.604	Down-regulation
AGC_PKC_PKCd_PRKCD_ST	P61073	CXCR4	Q05655	PRKCD	S330	L326P	326	Missense	distal	-4	no	8.413	8.274	EPSD	COSMIC	7.604	Down-regulation
AGC_PKC_PKCd_PRKCD_ST	P61073	CXCR4	Q05655	PRKCD	S330	G336E	336	Missense	distal	6	no	8.413	8.419	EPSD	COSMIC	7.604	Up-regulation
AGC_PKC_PKCd_PRKCD_ST	P61073	CXCR4	Q05655	PRKCD	S338	G336R	336	Missense	proximal	-2	no	2.460	8.224	EPSD	COSMIC	7.604	Gain
AGC_PKC_PKCd_PRKCD_ST	P61073	CXCR4	Q05655	PRKCD	S339	G336R	336	Missense	distal	-3	no	3.670	8.879	EPSD	COSMIC	7.604	Gain
AGC_PKC_PKCd_PRKCD_ST	P61073	CXCR4	Q05655	PRKCD	S341	E343K	343	Missense	proximal	2	no	3.598	9.353	EPSD	COSMIC	7.604	Gain
AGC_PKC_PKCd_PRKCD_ST	P49840	GSK3A	Q05655	PRKCD	S97	V104I	104	Missense	distal	7	no	13.735	13.731	EPSD	COSMIC;GDSC;CCLE	7.604	Down-regulation
AGC_PKC_PKCd_PRKCD_ST	P49840	GSK3A	Q05655	PRKCD	S266	Q269R	269	Missense	distal	3	no	6.621	7.698	EPSD	COSMIC	7.604	Gain
AGC_PKC_PKCd_PRKCD_ST	Q96C90	PPP1R14B	Q05655	PRKCD	S21	G18R	18	Missense	distal	-3	no	4.476	9.685	EPSD	COSMIC	7.604	Gain
AGC_PKC_PKCd_PRKCD_ST	Q96C90	PPP1R14B	Q05655	PRKCD	S142	T143I	143	Missense	proximal	1	no	8.494	8.407	EPSD	COSMIC	7.604	Down-regulation
AGC_PKC_PKCd_PRKCD_ST	Q96C90	PPP1R14B	Q05655	PRKCD	S142	R136W	136	Missense	distal	-6	no	8.494	9.086	EPSD	COSMIC	7.604	Up-regulation
AGC_PKC_PKCd_PRKCD_ST	P30273	FCER1G	Q05655	PRKCD	S69	G63D	63	Missense	distal	-6	no	9.696	9.658	PhosphoSitePlus	COSMIC	7.604	Down-regulation
AGC_PKC_PKCd_PRKCD_ST	P49841	GSK3B	Q05655	PRKCD	S2	S9F	9	Missense	distal	7	no	9.319	9.271	EPSD	COSMIC	7.604	Down-regulation
AGC_PKC_PKCd_PRKCD_ST	P49841	GSK3B	Q05655	PRKCD	S2	S2P	2	Missense	central	0	yes	9.319	0.000	EPSD	COSMIC	7.604	Loss
AGC_PKC_PKCd_PRKCD_ST	P49841	GSK3B	Q05655	PRKCD	T7	S9F	9	Missense	proximal	2	no	7.670	7.613	EPSD	COSMIC	7.604	Down-regulation
AGC_PKC_PKCd_PRKCD_ST	P49841	GSK3B	Q05655	PRKCD	T7	S2P	2	Missense	distal	-5	no	7.670	7.661	EPSD	COSMIC	7.604	Down-regulation
AGC_PKC_PKCd_PRKCD_ST	P49841	GSK3B	Q05655	PRKCD	S9	S9F	9	Missense	central	0	yes	8.872	0.000	PhosphoSitePlus	COSMIC	7.604	Loss
AGC_PKC_PKCd_PRKCD_ST	P49841	GSK3B	Q05655	PRKCD	S9	P16A	16	Missense	distal	7	no	8.872	8.875	PhosphoSitePlus	COSMIC	7.604	Up-regulation
AGC_PKC_PKCd_PRKCD_ST	P49841	GSK3B	Q05655	PRKCD	S13	S9F	9	Missense	distal	-4	no	9.596	9.727	EPSD	COSMIC	7.604	Up-regulation
AGC_PKC_PKCd_PRKCD_ST	P49841	GSK3B	Q05655	PRKCD	S13	P16A	16	Missense	distal	3	no	9.596	9.536	EPSD	COSMIC	7.604	Down-regulation
AGC_PKC_PKCd_PRKCD_ST	P49841	GSK3B	Q05655	PRKCD	S25	D31Y	31	Missense	distal	6	no	10.292	10.272	EPSD	COSMIC	7.604	Down-regulation
AGC_PKC_PKCd_PRKCD_ST	P49841	GSK3B	Q05655	PRKCD	S25	S25C	25	Missense	central	0	yes	10.292	0.000	EPSD	COSMIC	7.604	Loss
AGC_PKC_PKCd_PRKCD_ST	P49841	GSK3B	Q05655	PRKCD	S25	A22T	22	Missense	distal	-3	no	10.292	9.539	EPSD	COSMIC	7.604	Down-regulation
AGC_PKC_PKCd_PRKCD_ST	P49841	GSK3B	Q05655	PRKCD	S147	P154S	154	Missense	distal	7	no	8.102	8.131	EPSD	COSMIC	7.604	Up-regulation
AGC_PKC_PKCd_PRKCD_ST	P49841	GSK3B	Q05655	PRKCD	S147	Y146C	146	Missense	proximal	-1	no	8.102	8.111	EPSD	COSMIC	7.604	Up-regulation
AGC_PKC_PKCd_PRKCD_ST	P49841	GSK3B	Q05655	PRKCD	S147	R148Q	148	Missense	proximal	1	no	8.102	7.971	EPSD	COSMIC	7.604	Down-regulation
AGC_PKC_PKCd_PRKCD_ST	P49841	GSK3B	Q05655	PRKCD	S147	S147N	147	Missense	central	0	yes	8.102	0.000	EPSD	COSMIC	7.604	Loss
AGC_PKC_PKCd_PRKCD_ST	P49841	GSK3B	Q05655	PRKCD	S147	Y140C	140	Missense	distal	-7	no	8.102	8.103	EPSD	COSMIC	7.604	Up-regulation
AGC_PKC_PKCd_PRKCD_ST	P49841	GSK3B	Q05655	PRKCD	S147	A143G	143	Missense	distal	-4	no	8.102	8.171	EPSD	COSMIC	7.604	Up-regulation
AGC_PKC_PKCd_PRKCD_ST	P49841	GSK3B	Q05655	PRKCD	S147	R141S	141	Missense	distal	-6	no	8.102	8.302	EPSD	COSMIC	7.604	Up-regulation
AGC_PKC_PKCd_PRKCD_ST	P49841	GSK3B	Q05655	PRKCD	S203	Q206K	206	Missense	distal	3	no	6.677	7.761	EPSD	COSMIC	7.604	Gain
AGC_PKC_PKCd_PRKCD_ST	P40763	STAT3	Q05655	PRKCD	T412	H410Q	410	Missense	proximal	-2	no	11.390	10.931	EPSD	COSMIC	7.604	Down-regulation
AGC_PKC_PKCd_PRKCD_ST	P40763	STAT3	Q05655	PRKCD	T412	L413M	413	Missense	proximal	1	no	11.390	11.351	EPSD	COSMIC	7.604	Down-regulation
AGC_PKC_PKCd_PRKCD_ST	P40763	STAT3	Q05655	PRKCD	T412	G419W	419	Missense	distal	7	no	11.390	11.333	EPSD	COSMIC	7.604	Down-regulation
AGC_PKC_PKCd_PRKCD_ST	P40763	STAT3	Q05655	PRKCD	T412	L413R	413	Missense	proximal	1	no	11.390	11.539	EPSD	COSMIC	7.604	Up-regulation
AGC_PKC_PKCd_PRKCD_ST	P40763	STAT3	Q05655	PRKCD	T412	L413P	413	Missense	proximal	1	no	11.390	11.464	EPSD	COSMIC	7.604	Up-regulation
AGC_PKC_PKCd_PRKCD_ST	P40763	STAT3	Q05655	PRKCD	T412	F408L	408	Missense	distal	-4	no	11.390	11.419	EPSD	COSMIC	7.604	Up-regulation
AGC_PKC_PKCd_PRKCD_ST	P40763	STAT3	Q05655	PRKCD	S691	D698N	698	Missense	distal	7	no	7.798	7.791	EPSD	COSMIC	7.604	Down-regulation
AGC_PKC_PKCd_PRKCD_ST	P40763	STAT3	Q05655	PRKCD	S691	G684R	684	Missense	distal	-7	no	7.798	7.820	EPSD	COSMIC	7.604	Up-regulation
AGC_PKC_PKCd_PRKCD_ST	P40763	STAT3	Q05655	PRKCD	S727	D723N	723	Missense	distal	-4	no	8.961	8.986	PhosphoSitePlus	COSMIC	7.604	Up-regulation
AGC_PKC_PKCd_PRKCD_ST	O00429	DNM1L	Q05655	PRKCD	S40	G37R	37	Missense	distal	-3	no	6.494	11.703	EPSD	COSMIC	7.604	Gain
AGC_PKC_PKCd_PRKCD_ST	O00429	DNM1L	Q05655	PRKCD	T78	R76W	76	Missense	proximal	-2	no	9.612	3.359	EPSD	COSMIC	7.604	Loss
AGC_PKC_PKCd_PRKCD_ST	O00429	DNM1L	Q05655	PRKCD	T78	V85M	85	Missense	distal	7	no	9.612	9.618	EPSD	COSMIC	7.604	Up-regulation
AGC_PKC_PKCd_PRKCD_ST	O00429	DNM1L	Q05655	PRKCD	T78	T79A	79	Missense	proximal	1	no	9.612	9.550	EPSD	COSMIC	7.604	Down-regulation
AGC_PKC_PKCd_PRKCD_ST	O00429	DNM1L	Q05655	PRKCD	T79	R76W	76	Missense	distal	-3	no	8.492	3.195	EPSD	COSMIC	7.604	Loss
AGC_PKC_PKCd_PRKCD_ST	O00429	DNM1L	Q05655	PRKCD	T79	V85M	85	Missense	distal	6	no	8.492	8.493	EPSD	COSMIC	7.604	Up-regulation
AGC_PKC_PKCd_PRKCD_ST	O00429	DNM1L	Q05655	PRKCD	T79	T79A	79	Missense	central	0	yes	8.492	0.000	EPSD	COSMIC	7.604	Loss
AGC_PKC_PKCd_PRKCD_ST	O00429	DNM1L	Q05655	PRKCD	S126	G124R	124	Missense	proximal	-2	no	4.751	10.515	EPSD	COSMIC	7.604	Gain
AGC_PKC_PKCd_PRKCD_ST	O00429	DNM1L	Q05655	PRKCD	S563	K558E	558	Missense	distal	-5	no	9.004	8.646	EPSD	COSMIC	7.604	Down-regulation
AGC_PKC_PKCd_PRKCD_ST	O00429	DNM1L	Q05655	PRKCD	S563	D556N	556	Missense	distal	-7	no	9.004	9.001	EPSD	COSMIC	7.604	Down-regulation
AGC_PKC_PKCd_PRKCD_ST	O00429	DNM1L	Q05655	PRKCD	S563	T567S	567	Missense	distal	4	no	9.004	9.039	EPSD	COSMIC	7.604	Up-regulation
AGC_PKC_PKCd_PRKCD_ST	O00429	DNM1L	Q05655	PRKCD	S563	S563R	563	Missense	central	0	yes	9.004	0.000	EPSD	COSMIC	7.604	Loss
AGC_PKC_PKCd_PRKCD_ST	O00429	DNM1L	Q05655	PRKCD	S563	K558N	558	Missense	distal	-5	no	9.004	8.625	EPSD	COSMIC	7.604	Down-regulation
AGC_PKC_PKCd_PRKCD_ST	O00429	DNM1L	Q05655	PRKCD	S596	A598V	598	Missense	proximal	2	no	8.326	7.178	EPSD	COSMIC	7.604	Loss
AGC_PKC_PKCd_PRKCD_ST	O00429	DNM1L	Q05655	PRKCD	S596	K597N	597	Missense	proximal	1	no	8.326	8.130	EPSD	COSMIC	7.604	Down-regulation
AGC_PKC_PKCd_PRKCD_ST	O00429	DNM1L	Q05655	PRKCD	S637	P631H	631	Missense	distal	-6	no	18.032	18.057	EPSD	COSMIC	7.604	Up-regulation
AGC_PKC_PKCd_PRKCD_ST	O00429	DNM1L	Q05655	PRKCD	S637	R634L	634	Missense	distal	-3	no	18.032	12.846	EPSD	COSMIC	7.604	Down-regulation
AGC_PKC_PKCd_PRKCD_ST	O00429	DNM1L	Q05655	PRKCD	S637	R639L	639	Missense	proximal	2	no	18.032	11.155	EPSD	COSMIC	7.604	Down-regulation
AGC_PKC_PKCd_PRKCD_ST	O00429	DNM1L	Q05655	PRKCD	S637	R639W	639	Missense	proximal	2	no	18.032	11.359	EPSD	COSMIC	7.604	Down-regulation
AGC_PKC_PKCd_PRKCD_ST	Q09472	EP300	Q05655	PRKCD	S12	E7K	7	Missense	distal	-5	no	11.076	11.434	EPSD	COSMIC	7.604	Up-regulation
AGC_PKC_PKCd_PRKCD_ST	Q09472	EP300	Q05655	PRKCD	S12	P10R	10	Missense	proximal	-2	no	11.076	15.539	EPSD	COSMIC	7.604	Up-regulation
AGC_PKC_PKCd_PRKCD_ST	Q09472	EP300	Q05655	PRKCD	S12	G9R	9	Missense	distal	-3	no	11.076	16.285	EPSD	COSMIC	7.604	Up-regulation
AGC_PKC_PKCd_PRKCD_ST	Q09472	EP300	Q05655	PRKCD	S12	A13T	13	Missense	proximal	1	no	11.076	11.138	EPSD	COSMIC	7.604	Up-regulation
AGC_PKC_PKCd_PRKCD_ST	Q09472	EP300	Q05655	PRKCD	S12	A13V	13	Missense	proximal	1	no	11.076	11.060	EPSD	COSMIC	7.604	Down-regulation
AGC_PKC_PKCd_PRKCD_ST	Q09472	EP300	Q05655	PRKCD	S12	V5L	5	Missense	distal	-7	no	11.076	11.077	EPSD	COSMIC;CCLE	7.604	Up-regulation
AGC_PKC_PKCd_PRKCD_ST	Q09472	EP300	Q05655	PRKCD	S12	S12A	12	Missense	central	0	yes	11.076	0.000	EPSD	COSMIC	7.604	Loss
AGC_PKC_PKCd_PRKCD_ST	Q09472	EP300	Q05655	PRKCD	S19	A13T	13	Missense	distal	-6	no	9.230	9.153	EPSD	COSMIC	7.604	Down-regulation
AGC_PKC_PKCd_PRKCD_ST	Q09472	EP300	Q05655	PRKCD	S19	P21L	21	Missense	proximal	2	no	9.230	8.171	EPSD	COSMIC	7.604	Down-regulation
AGC_PKC_PKCd_PRKCD_ST	Q09472	EP300	Q05655	PRKCD	S19	A13V	13	Missense	distal	-6	no	9.230	9.355	EPSD	COSMIC	7.604	Up-regulation
AGC_PKC_PKCd_PRKCD_ST	Q09472	EP300	Q05655	PRKCD	S19	S12A	12	Missense	distal	-7	no	9.230	9.224	EPSD	COSMIC	7.604	Down-regulation
AGC_PKC_PKCd_PRKCD_ST	Q09472	EP300	Q05655	PRKCD	S20	A13T	13	Missense	distal	-7	no	8.222	8.223	EPSD	COSMIC	7.604	Up-regulation
AGC_PKC_PKCd_PRKCD_ST	Q09472	EP300	Q05655	PRKCD	S20	P21L	21	Missense	proximal	1	no	8.222	8.147	EPSD	COSMIC	7.604	Down-regulation
AGC_PKC_PKCd_PRKCD_ST	Q09472	EP300	Q05655	PRKCD	S20	A13V	13	Missense	distal	-7	no	8.222	8.216	EPSD	COSMIC	7.604	Down-regulation
AGC_PKC_PKCd_PRKCD_ST	Q09472	EP300	Q05655	PRKCD	S89	M95V	95	Missense	distal	6	no	9.743	9.742	PhosphoSitePlus	COSMIC	7.604	Down-regulation
AGC_PKC_PKCd_PRKCD_ST	Q09472	EP300	Q05655	PRKCD	S89	S87Y	87	Missense	proximal	-2	no	9.743	7.751	PhosphoSitePlus	COSMIC	7.604	Down-regulation
AGC_PKC_PKCd_PRKCD_ST	Q09472	EP300	Q05655	PRKCD	S395	R397Q	397	Missense	proximal	2	no	8.066	1.277	EPSD	COSMIC	7.604	Loss
AGC_PKC_PKCd_PRKCD_ST	Q09472	EP300	Q05655	PRKCD	S395	I400F	400	Missense	distal	5	no	8.066	8.189	EPSD	COSMIC	7.604	Up-regulation
AGC_PKC_PKCd_PRKCD_ST	Q09472	EP300	Q05655	PRKCD	S395	I400S	400	Missense	distal	5	no	8.066	8.399	EPSD	COSMIC	7.604	Up-regulation
AGC_PKC_PKCd_PRKCD_ST	Q09472	EP300	Q05655	PRKCD	S395	C393S	393	Missense	proximal	-2	no	8.066	9.212	EPSD	COSMIC	7.604	Up-regulation
AGC_PKC_PKCd_PRKCD_ST	Q09472	EP300	Q05655	PRKCD	S395	A394S	394	Missense	proximal	-1	no	8.066	8.144	EPSD	COSMIC	7.604	Up-regulation
AGC_PKC_PKCd_PRKCD_ST	Q09472	EP300	Q05655	PRKCD	S395	R397P	397	Missense	proximal	2	no	8.066	2.248	EPSD	COSMIC	7.604	Loss
AGC_PKC_PKCd_PRKCD_ST	Q09472	EP300	Q05655	PRKCD	T885	P882R	882	Missense	distal	-3	no	6.617	10.860	EPSD	COSMIC	7.604	Gain
AGC_PKC_PKCd_PRKCD_ST	Q09472	EP300	Q05655	PRKCD	S1009	E1011K	1011	Missense	proximal	2	no	5.905	11.660	EPSD	COSMIC	7.604	Gain
AGC_PKC_PKCd_PRKCD_ST	Q09472	EP300	Q05655	PRKCD	S1044	S1037L	1037	Missense	distal	-7	no	8.371	8.360	EPSD	COSMIC	7.604	Down-regulation
AGC_PKC_PKCd_PRKCD_ST	Q09472	EP300	Q05655	PRKCD	S1044	G1042R	1042	Missense	proximal	-2	no	8.371	14.135	EPSD	COSMIC	7.604	Up-regulation
AGC_PKC_PKCd_PRKCD_ST	Q09472	EP300	Q05655	PRKCD	S1044	P1051L	1051	Missense	distal	7	no	8.371	8.341	EPSD	COSMIC	7.604	Down-regulation
AGC_PKC_PKCd_PRKCD_ST	Q09472	EP300	Q05655	PRKCD	T1135	S1136P	1136	Missense	proximal	1	no	12.232	12.251	EPSD	COSMIC	7.604	Up-regulation
AGC_PKC_PKCd_PRKCD_ST	Q09472	EP300	Q05655	PRKCD	T1135	C1142F	1142	Missense	distal	7	no	12.232	12.258	EPSD	COSMIC	7.604	Up-regulation
AGC_PKC_PKCd_PRKCD_ST	Q09472	EP300	Q05655	PRKCD	T1135	R1137L	1137	Missense	proximal	2	no	12.232	5.354	EPSD	COSMIC	7.604	Loss
AGC_PKC_PKCd_PRKCD_ST	Q09472	EP300	Q05655	PRKCD	T1135	Y1141N	1141	Missense	distal	6	no	12.232	12.246	EPSD	COSMIC	7.604	Up-regulation
AGC_PKC_PKCd_PRKCD_ST	Q09472	EP300	Q05655	PRKCD	S1295	T1300I	1300	Missense	distal	5	no	12.842	12.605	EPSD	COSMIC	7.604	Down-regulation
AGC_PKC_PKCd_PRKCD_ST	Q09472	EP300	Q05655	PRKCD	S1295	L1298R	1298	Missense	distal	3	no	12.842	13.985	EPSD	COSMIC	7.604	Up-regulation
AGC_PKC_PKCd_PRKCD_ST	Q09472	EP300	Q05655	PRKCD	T1296	L1298R	1298	Missense	proximal	2	no	2.648	9.525	EPSD	COSMIC	7.604	Gain
AGC_PKC_PKCd_PRKCD_ST	Q09472	EP300	Q05655	PRKCD	S1643	L1639P	1639	Missense	distal	-4	no	9.055	8.916	EPSD	COSMIC	7.604	Down-regulation
AGC_PKC_PKCd_PRKCD_ST	Q09472	EP300	Q05655	PRKCD	S1643	H1638Y	1638	Missense	distal	-5	no	9.055	8.914	EPSD	COSMIC	7.604	Down-regulation
AGC_PKC_PKCd_PRKCD_ST	Q09472	EP300	Q05655	PRKCD	S1643	S1642F	1642	Missense	proximal	-1	no	9.055	8.948	EPSD	COSMIC	7.604	Down-regulation
AGC_PKC_PKCd_PRKCD_ST	Q09472	EP300	Q05655	PRKCD	S1730	S1730Y	1730	Missense	central	0	yes	7.716	0.000	EPSD	COSMIC	7.604	Loss
AGC_PKC_PKCd_PRKCD_ST	Q09472	EP300	Q05655	PRKCD	S1730	S1730F	1730	Missense	central	0	yes	7.716	0.000	EPSD	COSMIC	7.604	Loss
AGC_PKC_PKCd_PRKCD_ST	Q09472	EP300	Q05655	PRKCD	S1730	R1732H	1732	Missense	proximal	2	no	7.716	2.155	EPSD	COSMIC	7.604	Loss
AGC_PKC_PKCd_PRKCD_ST	Q09472	EP300	Q05655	PRKCD	S1734	S1730Y	1730	Missense	distal	-4	no	13.068	13.289	EPSD	COSMIC	7.604	Up-regulation
AGC_PKC_PKCd_PRKCD_ST	Q09472	EP300	Q05655	PRKCD	S1734	S1730F	1730	Missense	distal	-4	no	13.068	13.199	EPSD	COSMIC	7.604	Up-regulation
AGC_PKC_PKCd_PRKCD_ST	Q09472	EP300	Q05655	PRKCD	S1734	R1732H	1732	Missense	proximal	-2	no	13.068	8.093	EPSD	COSMIC	7.604	Down-regulation
AGC_PKC_PKCd_PRKCD_ST	Q09472	EP300	Q05655	PRKCD	S2315	P2314T	2314	Missense	proximal	-1	no	9.233	9.212	EPSD	COSMIC	7.604	Down-regulation
AGC_PKC_PKCd_PRKCD_ST	Q09472	EP300	Q05655	PRKCD	S2315	R2317W	2317	Missense	proximal	2	no	9.233	2.560	EPSD	COSMIC	7.604	Loss
AGC_PKC_PKCd_PRKCD_ST	Q09472	EP300	Q05655	PRKCD	S2315	P2312S	2312	Missense	distal	-3	no	9.233	8.901	EPSD	COSMIC	7.604	Down-regulation
AGC_PKC_PKCd_PRKCD_ST	Q09472	EP300	Q05655	PRKCD	S2320	H2324T	2324	Missense	distal	4	no	8.027	8.064	EPSD	COSMIC	7.604	Up-regulation
AGC_PKC_PKCd_PRKCD_ST	Q09472	EP300	Q05655	PRKCD	S2320	P2314T	2314	Missense	distal	-6	no	8.027	7.991	EPSD	COSMIC	7.604	Down-regulation
AGC_PKC_PKCd_PRKCD_ST	Q09472	EP300	Q05655	PRKCD	S2320	R2317W	2317	Missense	distal	-3	no	8.027	2.730	EPSD	COSMIC	7.604	Loss
AGC_PKC_PKCd_PRKCD_ST	Q09472	EP300	Q05655	PRKCD	S2320	H2324Y	2324	Missense	distal	4	no	8.027	7.773	EPSD	COSMIC	7.604	Down-regulation
AGC_PKC_PKCd_PRKCD_ST	Q09472	EP300	Q05655	PRKCD	S2328	H2324T	2324	Missense	distal	-4	no	10.587	10.579	EPSD	COSMIC	7.604	Down-regulation
AGC_PKC_PKCd_PRKCD_ST	Q09472	EP300	Q05655	PRKCD	S2328	H2324Y	2324	Missense	distal	-4	no	10.587	10.748	EPSD	COSMIC	7.604	Up-regulation
AGC_PKC_PKCd_PRKCD_ST	Q01543	FLI1	Q05655	PRKCD	S76	E78K	78	Missense	proximal	2	no	2.223	7.978	EPSD	COSMIC	7.604	Gain
AGC_PKC_PKCd_PRKCD_ST	Q01543	FLI1	Q05655	PRKCD	S79	P80T	80	Missense	proximal	1	no	8.546	8.509	EPSD	COSMIC	7.604	Down-regulation
AGC_PKC_PKCd_PRKCD_ST	Q01543	FLI1	Q05655	PRKCD	S79	M73I	73	Missense	distal	-6	no	8.546	8.576	EPSD	COSMIC	7.604	Up-regulation
AGC_PKC_PKCd_PRKCD_ST	Q01543	FLI1	Q05655	PRKCD	S79	V85I	85	Missense	distal	6	no	8.546	8.542	EPSD	COSMIC	7.604	Down-regulation
AGC_PKC_PKCd_PRKCD_ST	Q01543	FLI1	Q05655	PRKCD	S79	E78K	78	Missense	proximal	-1	no	8.546	8.720	EPSD	COSMIC	7.604	Up-regulation
AGC_PKC_PKCd_PRKCD_ST	Q01543	FLI1	Q05655	PRKCD	S215	S212N	212	Missense	distal	-3	no	13.714	13.149	EPSD	COSMIC	7.604	Down-regulation
AGC_PKC_PKCd_PRKCD_ST	Q01543	FLI1	Q05655	PRKCD	S215	S212L	212	Missense	distal	-3	no	13.714	13.103	EPSD	COSMIC	7.604	Down-regulation
AGC_PKC_PKCd_PRKCD_ST	Q01543	FLI1	Q05655	PRKCD	S215	S221F	221	Missense	distal	6	no	13.714	13.687	EPSD	COSMIC	7.604	Down-regulation
AGC_PKC_PKCd_PRKCD_ST	Q01543	FLI1	Q05655	PRKCD	S224	A229V	229	Missense	distal	5	no	8.073	7.952	EPSD	COSMIC	7.604	Down-regulation
AGC_PKC_PKCd_PRKCD_ST	Q01543	FLI1	Q05655	PRKCD	S224	S221F	221	Missense	distal	-3	no	8.073	8.124	EPSD	COSMIC	7.604	Up-regulation
AGC_PKC_PKCd_PRKCD_ST	Q01543	FLI1	Q05655	PRKCD	S224	V225A	225	Missense	proximal	1	no	8.073	8.089	EPSD	COSMIC	7.604	Up-regulation
AGC_PKC_PKCd_PRKCD_ST	P08581	MET	Q05655	PRKCD	S985	T992I	992	Missense	distal	7	no	12.233	12.172	PhosphoSitePlus	COSMIC	7.604	Down-regulation
AGC_PKC_PKCd_PRKCD_ST	P08581	MET	Q05655	PRKCD	S985	V984A	984	Missense	proximal	-1	no	12.233	12.283	PhosphoSitePlus	COSMIC	7.604	Up-regulation
AGC_PKC_PKCd_PRKCD_ST	P08581	MET	Q05655	PRKCD	S985	A986D	986	Missense	proximal	1	no	12.233	12.236	PhosphoSitePlus	COSMIC	7.604	Up-regulation
AGC_PKC_PKCd_PRKCD_ST	P08581	MET	Q05655	PRKCD	S985	R987Q	987	Missense	proximal	2	no	12.233	5.444	PhosphoSitePlus	COSMIC	7.604	Loss
AGC_PKC_PKCd_PRKCD_ST	P08581	MET	Q05655	PRKCD	S985	L980V	980	Missense	distal	-5	no	12.233	12.234	PhosphoSitePlus	COSMIC	7.604	Up-regulation
AGC_PKC_PKCd_PRKCD_ST	P08581	MET	Q05655	PRKCD	S985	P991S	991	Missense	distal	6	no	12.233	12.239	PhosphoSitePlus	COSMIC	7.604	Up-regulation
AGC_PKC_PKCd_PRKCD_ST	P08581	MET	Q05655	PRKCD	S985	P978S	978	Missense	distal	-7	no	12.233	12.234	PhosphoSitePlus	COSMIC	7.604	Up-regulation
AGC_PKC_PKCd_PRKCD_ST	P08581	MET	Q05655	PRKCD	S997	E999K	999	Missense	proximal	2	no	1.863	7.618	EPSD	COSMIC	7.604	Gain
AGC_PKC_PKCd_PRKCD_ST	P08581	MET	Q05655	PRKCD	S1236	H1238R	1238	Missense	proximal	2	no	2.613	8.174	EPSD	COSMIC	7.604	Gain
AGC_PKC_PKCd_PRKCD_ST	P08581	MET	Q05655	PRKCD	T1241	H1238R	1238	Missense	distal	-3	no	4.650	8.905	EPSD	COSMIC	7.604	Gain
AGC_PKC_PKCd_PRKCD_ST	P08581	MET	Q05655	PRKCD	T1261	T1261I	1261	Missense	central	0	yes	8.120	0.000	EPSD	COSMIC	7.604	Loss
AGC_PKC_PKCd_PRKCD_ST	P08581	MET	Q05655	PRKCD	T1261	L1255M	1255	Missense	distal	-6	no	8.120	8.114	EPSD	COSMIC	7.604	Down-regulation
AGC_PKC_PKCd_PRKCD_ST	P08581	MET	Q05655	PRKCD	T1261	V1266M	1266	Missense	distal	5	no	8.120	8.119	EPSD	COSMIC	7.604	Down-regulation
AGC_PKC_PKCd_PRKCD_ST	P08581	MET	Q05655	PRKCD	T1261	V1266A	1266	Missense	distal	5	no	8.120	8.241	EPSD	COSMIC	7.604	Up-regulation
AGC_PKC_PKCd_PRKCD_ST	Q9UQ80	PA2G4	Q05655	PRKCD	S252	G256R	256	Missense	distal	4	no	7.377	8.045	EPSD	COSMIC	7.604	Gain
AGC_PKC_PKCd_PRKCD_ST	Q9UQ80	PA2G4	Q05655	PRKCD	T261	T261A	261	Missense	central	0	yes	9.778	0.000	EPSD	COSMIC	7.604	Loss
AGC_PKC_PKCd_PRKCD_ST	Q9UQ80	PA2G4	Q05655	PRKCD	T261	G256R	256	Missense	distal	-5	no	9.778	10.191	EPSD	COSMIC	7.604	Up-regulation
AGC_PKC_PKCd_PRKCD_ST	Q9UQ80	PA2G4	Q05655	PRKCD	S262	T261A	261	Missense	proximal	-1	no	7.689	7.673	EPSD	COSMIC	7.604	Down-regulation
AGC_PKC_PKCd_PRKCD_ST	Q9UQ80	PA2G4	Q05655	PRKCD	S262	G256R	256	Missense	distal	-6	no	7.689	7.297	EPSD	COSMIC	7.604	Loss
AGC_PKC_PKCd_PRKCD_ST	Q9UQ80	PA2G4	Q05655	PRKCD	T279	T279A	279	Missense	central	0	yes	8.141	0.000	EPSD	COSMIC	7.604	Loss
AGC_PKC_PKCd_PRKCD_ST	O15350	TP73	Q05655	PRKCD	S289	G292C	292	Missense	distal	3	no	8.553	8.416	PhosphoSitePlus	COSMIC	7.604	Down-regulation
AGC_PKC_PKCd_PRKCD_ST	O15350	TP73	Q05655	PRKCD	S326	S333R	333	Missense	distal	7	no	9.334	9.398	EPSD	COSMIC	7.604	Up-regulation
AGC_PKC_PKCd_PRKCD_ST	O15350	TP73	Q05655	PRKCD	S333	S333R	333	Missense	central	0	yes	7.670	0.000	EPSD	COSMIC	7.604	Loss
AGC_PKC_PKCd_PRKCD_ST	O15350	TP73	Q05655	PRKCD	S333	P335L	335	Missense	proximal	2	no	7.670	6.610	EPSD	COSMIC;GDSC;CCLE	7.604	Loss
AGC_PKC_PKCd_PRKCD_ST	P12931	SRC	Q05655	PRKCD	S12	K9T	9	Missense	distal	-3	no	14.804	10.747	PhosphoSitePlus	COSMIC	7.604	Down-regulation
AGC_PKC_PKCd_PRKCD_ST	P12931	SRC	Q05655	PRKCD	S12	R16H	16	Missense	distal	4	no	14.804	14.261	PhosphoSitePlus	COSMIC	7.604	Down-regulation
AGC_PKC_PKCd_PRKCD_ST	P12931	SRC	Q05655	PRKCD	S12	R15C	15	Missense	distal	3	no	14.804	13.530	PhosphoSitePlus	COSMIC	7.604	Down-regulation
AGC_PKC_PKCd_PRKCD_ST	P12931	SRC	Q05655	PRKCD	S17	R16H	16	Missense	proximal	-1	no	14.401	14.256	EPSD	COSMIC	7.604	Down-regulation
AGC_PKC_PKCd_PRKCD_ST	P12931	SRC	Q05655	PRKCD	S17	A21T	21	Missense	distal	4	no	14.401	14.432	EPSD	COSMIC	7.604	Up-regulation
AGC_PKC_PKCd_PRKCD_ST	P12931	SRC	Q05655	PRKCD	S17	R15C	15	Missense	proximal	-2	no	14.401	8.407	EPSD	COSMIC	7.604	Down-regulation
AGC_PKC_PKCd_PRKCD_ST	P12931	SRC	Q05655	PRKCD	S17	P20S	20	Missense	distal	3	no	14.401	14.407	EPSD	COSMIC	7.604	Up-regulation
AGC_PKC_PKCd_PRKCD_ST	P12931	SRC	Q05655	PRKCD	S51	A44V	44	Missense	distal	-7	no	8.706	8.700	EPSD	COSMIC	7.604	Down-regulation
AGC_PKC_PKCd_PRKCD_ST	P12931	SRC	Q05655	PRKCD	S51	D45N	45	Missense	distal	-6	no	8.706	8.752	EPSD	COSMIC	7.604	Up-regulation
AGC_PKC_PKCd_PRKCD_ST	P12931	SRC	Q05655	PRKCD	S51	A57V	57	Missense	distal	6	no	8.706	8.689	EPSD	COSMIC	7.604	Down-regulation
AGC_PKC_PKCd_PRKCD_ST	P12931	SRC	Q05655	PRKCD	S51	G46S	46	Missense	distal	-5	no	8.706	8.845	EPSD	COSMIC	7.604	Up-regulation
AGC_PKC_PKCd_PRKCD_ST	P12931	SRC	Q05655	PRKCD	S180	V177M	177	Missense	distal	-3	no	8.337	8.315	EPSD	COSMIC	7.604	Down-regulation
AGC_PKC_PKCd_PRKCD_ST	P12931	SRC	Q05655	PRKCD	S180	A186T	186	Missense	distal	6	no	8.337	8.348	EPSD	COSMIC	7.604	Up-regulation
AGC_PKC_PKCd_PRKCD_ST	P12931	SRC	Q05655	PRKCD	T443	V448L	448	Missense	distal	5	no	10.085	10.152	EPSD	COSMIC	7.604	Up-regulation
AGC_PKC_PKCd_PRKCD_ST	P12931	SRC	Q05655	PRKCD	T443	Y439S	439	Missense	distal	-4	no	10.085	9.864	EPSD	COSMIC	7.604	Down-regulation
AGC_PKC_PKCd_PRKCD_ST	P12931	SRC	Q05655	PRKCD	T443	L438R	438	Missense	distal	-5	no	10.085	10.515	EPSD	COSMIC	7.604	Up-regulation
AGC_PKC_PKCd_PRKCD_ST	P12931	SRC	Q05655	PRKCD	T511	E508K	508	Missense	distal	-3	no	4.465	8.850	EPSD	COSMIC	7.604	Gain
AGC_PKC_PKCd_PRKCD_ST	P12931	SRC	Q05655	PRKCD	T511	E513K	513	Missense	proximal	2	no	4.465	10.220	EPSD	COSMIC	7.604	Gain
AGC_PKC_PKCd_PRKCD_ST	P52757	CHN2	Q05655	PRKCD	S85	P89S	89	Missense	distal	4	no	13.564	13.525	EPSD	COSMIC	7.604	Down-regulation
AGC_PKC_PKCd_PRKCD_ST	P52757	CHN2	Q05655	PRKCD	S85	R87L	87	Missense	proximal	2	no	13.564	6.686	EPSD	COSMIC	7.604	Loss
AGC_PKC_PKCd_PRKCD_ST	P52757	CHN2	Q05655	PRKCD	S85	A79V	79	Missense	distal	-6	no	13.564	13.688	EPSD	COSMIC	7.604	Up-regulation
AGC_PKC_PKCd_PRKCD_ST	P52757	CHN2	Q05655	PRKCD	S85	P89T	89	Missense	distal	4	no	13.564	13.490	EPSD	COSMIC	7.604	Down-regulation
AGC_PKC_PKCd_PRKCD_ST	P52757	CHN2	Q05655	PRKCD	S85	L82F	82	Missense	distal	-3	no	13.564	14.227	EPSD	COSMIC	7.604	Up-regulation
AGC_PKC_PKCd_PRKCD_ST	P52757	CHN2	Q05655	PRKCD	S167	L170V	170	Missense	distal	3	no	11.819	11.808	EPSD	COSMIC	7.604	Down-regulation
AGC_PKC_PKCd_PRKCD_ST	P52757	CHN2	Q05655	PRKCD	S167	L161I	161	Missense	distal	-6	no	11.819	11.843	EPSD	COSMIC	7.604	Up-regulation
AGC_PKC_PKCd_PRKCD_ST	P52757	CHN2	Q05655	PRKCD	S167	R168K	168	Missense	proximal	1	no	11.819	11.836	EPSD	COSMIC;GDSC;CCLE	7.604	Up-regulation
AGC_PKC_PKCd_PRKCD_ST	P52757	CHN2	Q05655	PRKCD	S171	L170V	170	Missense	proximal	-1	no	12.251	12.240	PhosphoSitePlus	COSMIC	7.604	Down-regulation
AGC_PKC_PKCd_PRKCD_ST	P52757	CHN2	Q05655	PRKCD	S171	R178I	178	Missense	distal	7	no	12.251	12.118	PhosphoSitePlus	COSMIC	7.604	Down-regulation
AGC_PKC_PKCd_PRKCD_ST	P52757	CHN2	Q05655	PRKCD	S171	R168K	168	Missense	distal	-3	no	12.251	11.216	PhosphoSitePlus	COSMIC;GDSC;CCLE	7.604	Down-regulation
AGC_PKC_PKCd_PRKCD_ST	P52757	CHN2	Q05655	PRKCD	S171	R178K	178	Missense	distal	7	no	12.251	12.280	PhosphoSitePlus	COSMIC	7.604	Up-regulation
AGC_PKC_PKCd_PRKCD_ST	P52757	CHN2	Q05655	PRKCD	S171	N175H	175	Missense	distal	4	no	12.251	12.361	PhosphoSitePlus	COSMIC	7.604	Up-regulation
AGC_PKC_PKCd_PRKCD_ST	P30086	PEBP1	Q05655	PRKCD	S52	R49T	49	Missense	distal	-3	no	7.624	2.532	EPSD	COSMIC;GDSC;CCLE	7.604	Loss
AGC_PKC_PKCd_PRKCD_ST	P30086	PEBP1	Q05655	PRKCD	S52	D59E	59	Missense	distal	7	no	7.624	7.621	EPSD	COSMIC	7.604	Down-regulation
AGC_PKC_PKCd_PRKCD_ST	P30086	PEBP1	Q05655	PRKCD	S75	P74L	74	Missense	proximal	-1	no	7.860	7.784	EPSD	COSMIC	7.604	Down-regulation
AGC_PKC_PKCd_PRKCD_ST	P30086	PEBP1	Q05655	PRKCD	S139	L138H	138	Missense	proximal	-1	no	8.671	8.717	EPSD	COSMIC	7.604	Up-regulation
AGC_PKC_PKCd_PRKCD_ST	P30086	PEBP1	Q05655	PRKCD	S139	E135K	135	Missense	distal	-4	no	8.671	8.279	EPSD	COSMIC	7.604	Down-regulation
AGC_PKC_PKCd_PRKCD_ST	P30086	PEBP1	Q05655	PRKCD	S153	R155G	155	Missense	proximal	2	no	14.402	8.070	PhosphoSitePlus	COSMIC	7.604	Down-regulation
AGC_PKC_PKCd_PRKCD_ST	Q8IV61	RASGRP3	Q05655	PRKCD	T133	R135T	135	Missense	proximal	2	no	19.126	12.871	PhosphoSitePlus	COSMIC;CCLE	7.604	Down-regulation
AGC_PKC_PKCd_PRKCD_ST	Q8IV61	RASGRP3	Q05655	PRKCD	T133	M129I	129	Missense	distal	-4	no	19.126	19.175	PhosphoSitePlus	COSMIC	7.604	Up-regulation
AGC_PKC_PKCd_PRKCD_ST	Q8IV61	RASGRP3	Q05655	PRKCD	S385	S387L	387	Missense	proximal	2	no	8.525	7.710	EPSD	COSMIC	7.604	Down-regulation
AGC_PKC_PKCd_PRKCD_ST	Q8IV61	RASGRP3	Q05655	PRKCD	S385	S387P	387	Missense	proximal	2	no	8.525	8.769	EPSD	COSMIC	7.604	Up-regulation
AGC_PKC_PKCd_PRKCD_ST	Q8IV61	RASGRP3	Q05655	PRKCD	S385	P392H	392	Missense	distal	7	no	8.525	8.531	EPSD	COSMIC	7.604	Up-regulation
AGC_PKC_PKCd_PRKCD_ST	Q8IV61	RASGRP3	Q05655	PRKCD	S385	Q388R	388	Missense	distal	3	no	8.525	9.602	EPSD	COSMIC	7.604	Up-regulation
AGC_PKC_PKCd_PRKCD_ST	Q8IV61	RASGRP3	Q05655	PRKCD	S385	S385Y	385	Missense	central	0	yes	8.525	0.000	EPSD	COSMIC	7.604	Loss
AGC_PKC_PKCd_PRKCD_ST	Q8IV61	RASGRP3	Q05655	PRKCD	S385	K386I	386	Missense	proximal	1	no	8.525	8.309	EPSD	COSMIC	7.604	Down-regulation
AGC_PKC_PKCd_PRKCD_ST	Q8IV61	RASGRP3	Q05655	PRKCD	S391	Q388R	388	Missense	distal	-3	no	2.916	8.074	EPSD	COSMIC	7.604	Gain
AGC_PKC_PKCd_PRKCD_ST	Q8IV61	RASGRP3	Q05655	PRKCD	S552	P551L	551	Missense	proximal	-1	no	8.325	8.249	EPSD	COSMIC	7.604	Down-regulation
AGC_PKC_PKCd_PRKCD_ST	Q8IV61	RASGRP3	Q05655	PRKCD	S552	P551S	551	Missense	proximal	-1	no	8.325	8.365	EPSD	COSMIC	7.604	Up-regulation
AGC_PKC_PKCd_PRKCD_ST	Q8IV61	RASGRP3	Q05655	PRKCD	S552	A548S	548	Missense	distal	-4	no	8.325	8.243	EPSD	COSMIC	7.604	Down-regulation
AGC_PKC_PKCd_PRKCD_ST	Q8IV61	RASGRP3	Q05655	PRKCD	S597	R604K	604	Missense	distal	7	no	9.497	9.526	EPSD	COSMIC;GDSC;CCLE	7.604	Up-regulation
AGC_PKC_PKCd_PRKCD_ST	Q8IV61	RASGRP3	Q05655	PRKCD	S597	R599C	599	Missense	proximal	2	no	9.497	2.619	EPSD	COSMIC	7.604	Loss
AGC_PKC_PKCd_PRKCD_ST	Q8IV61	RASGRP3	Q05655	PRKCD	S597	S597Y	597	Missense	central	0	yes	9.497	0.000	EPSD	COSMIC	7.604	Loss
AGC_PKC_PKCd_PRKCD_ST	Q8IV61	RASGRP3	Q05655	PRKCD	S598	R604K	604	Missense	distal	6	no	7.876	7.879	EPSD	COSMIC;GDSC;CCLE	7.604	Up-regulation
AGC_PKC_PKCd_PRKCD_ST	Q8IV61	RASGRP3	Q05655	PRKCD	S598	R599C	599	Missense	proximal	1	no	7.876	7.663	EPSD	COSMIC	7.604	Down-regulation
AGC_PKC_PKCd_PRKCD_ST	Q8IV61	RASGRP3	Q05655	PRKCD	S598	S597Y	597	Missense	proximal	-1	no	7.876	7.731	EPSD	COSMIC	7.604	Down-regulation
CAMK_PIM_PIM2_ST	P14618	PKM	Q9P1W9	PIM2	T15	G9R	9	Missense	distal	-6	no	3.906	4.751	EPSD	COSMIC	4.322	Gain
CAMK_PIM_PIM2_ST	P14618	PKM	Q9P1W9	PIM2	S37	R32L	32	Missense	distal	-5	no	4.471	2.263	EPSD	COSMIC	4.322	Loss
CAMK_PIM_PIM2_ST	P14618	PKM	Q9P1W9	PIM2	S127	G128V	128	Missense	proximal	1	no	5.576	5.921	EPSD	COSMIC	4.322	Up-regulation
CAMK_PIM_PIM2_ST	P14618	PKM	Q9P1W9	PIM2	S127	T121S	121	Missense	distal	-6	no	5.576	5.672	EPSD	COSMIC;GDSC;CCLE	4.322	Up-regulation
CAMK_PIM_PIM2_ST	P14618	PKM	Q9P1W9	PIM2	T454	V453M	453	Missense	proximal	-1	no	11.856	11.706	PhosphoSitePlus	COSMIC	4.322	Down-regulation
CAMK_PIM_PIM2_ST	P14618	PKM	Q9P1W9	PIM2	T454	R455Q	455	Missense	proximal	1	no	11.856	11.810	PhosphoSitePlus	COSMIC	4.322	Down-regulation
CAMK_PIM_PIM2_ST	P14618	PKM	Q9P1W9	PIM2	T454	R447C	447	Missense	distal	-7	no	11.856	11.475	PhosphoSitePlus	COSMIC	4.322	Down-regulation
CAMK_PIM_PIM2_ST	P14618	PKM	Q9P1W9	PIM2	T454	V453L	453	Missense	proximal	-1	no	11.856	11.532	PhosphoSitePlus	COSMIC	4.322	Down-regulation
CAMK_PIM_PIM2_ST	P52789	HK2	Q9P1W9	PIM2	S408	G414D	414	Missense	distal	6	no	4.803	4.814	EPSD	COSMIC	4.322	Up-regulation
CAMK_PIM_PIM2_ST	P52789	HK2	Q9P1W9	PIM2	S408	S415P	415	Missense	distal	7	no	4.803	4.641	EPSD	COSMIC	4.322	Down-regulation
CAMK_PIM_PIM2_ST	P52789	HK2	Q9P1W9	PIM2	S408	V412A	412	Missense	distal	4	no	4.803	4.312	EPSD	COSMIC	4.322	Loss
CAMK_PIM_PIM2_ST	P52789	HK2	Q9P1W9	PIM2	T409	G414D	414	Missense	distal	5	no	4.326	4.397	EPSD	COSMIC	4.322	Up-regulation
CAMK_PIM_PIM2_ST	P52789	HK2	Q9P1W9	PIM2	T409	S415P	415	Missense	distal	6	no	4.326	4.454	EPSD	COSMIC	4.322	Up-regulation
CAMK_PIM_PIM2_ST	P52789	HK2	Q9P1W9	PIM2	T409	V412A	412	Missense	distal	3	no	4.326	4.611	EPSD	COSMIC	4.322	Up-regulation
CAMK_PIM_PIM2_ST	P52789	HK2	Q9P1W9	PIM2	T473	H467Y	467	Missense	distal	-6	no	7.049	6.893	PhosphoSitePlus	COSMIC	4.322	Down-regulation
CAMK_PIM_PIM2_ST	P52789	HK2	Q9P1W9	PIM2	T473	L477V	477	Missense	distal	4	no	7.049	6.690	PhosphoSitePlus	COSMIC	4.322	Down-regulation
CAMK_PIM_PIM2_ST	P38936	CDKN1A	Q9P1W9	PIM2	S31	R32C	32	Missense	proximal	1	no	4.430	4.777	EPSD	COSMIC	4.322	Up-regulation
CAMK_PIM_PIM2_ST	P38936	CDKN1A	Q9P1W9	PIM2	S31	P24S	24	Missense	distal	-7	no	4.430	4.158	EPSD	COSMIC	4.322	Loss
CAMK_PIM_PIM2_ST	P38936	CDKN1A	Q9P1W9	PIM2	S31	S27T	27	Missense	distal	-4	no	4.430	4.478	EPSD	COSMIC	4.322	Up-regulation
CAMK_PIM_PIM2_ST	P38936	CDKN1A	Q9P1W9	PIM2	S98	T97I	97	Missense	proximal	-1	no	5.286	4.994	EPSD	COSMIC	4.322	Down-regulation
CAMK_PIM_PIM2_ST	P38936	CDKN1A	Q9P1W9	PIM2	T145	D149N	149	Missense	distal	4	no	11.610	11.386	PhosphoSitePlus;EPSD	COSMIC	4.322	Down-regulation
CAMK_PIM_PIM2_ST	P38936	CDKN1A	Q9P1W9	PIM2	T145	R143W	143	Missense	proximal	-2	no	11.610	10.704	PhosphoSitePlus;EPSD	COSMIC;GDSC;CCLE	4.322	Down-regulation
CAMK_PIM_PIM2_ST	P38936	CDKN1A	Q9P1W9	PIM2	T145	Q138E	138	Missense	distal	-7	no	11.610	11.570	PhosphoSitePlus;EPSD	COSMIC	4.322	Down-regulation
CAMK_PIM_PIM2_ST	P38936	CDKN1A	Q9P1W9	PIM2	T145	G139C	139	Missense	distal	-6	no	11.610	11.647	PhosphoSitePlus;EPSD	COSMIC	4.322	Up-regulation
CAMK_PIM_PIM2_ST	P38936	CDKN1A	Q9P1W9	PIM2	S146	T145S	145	Missense	proximal	-1	no	9.959	9.593	EPSD;PhosphoSitePlus	COSMIC	4.322	Down-regulation
CAMK_PIM_PIM2_ST	P38936	CDKN1A	Q9P1W9	PIM2	S146	D149N	149	Missense	distal	3	no	9.959	9.842	EPSD;PhosphoSitePlus	COSMIC	4.322	Down-regulation
CAMK_PIM_PIM2_ST	P38936	CDKN1A	Q9P1W9	PIM2	S146	R143W	143	Missense	distal	-3	no	9.959	8.140	EPSD;PhosphoSitePlus	COSMIC;GDSC;CCLE	4.322	Down-regulation
CAMK_PIM_PIM2_ST	P38936	CDKN1A	Q9P1W9	PIM2	S146	G139C	139	Missense	distal	-7	no	9.959	9.585	EPSD;PhosphoSitePlus	COSMIC	4.322	Down-regulation
CAMK_PIM_PIM2_ST	P38936	CDKN1A	Q9P1W9	PIM2	S153	R156W	156	Missense	distal	3	no	4.399	4.320	EPSD	COSMIC;GDSC;CCLE	4.322	Loss
CAMK_PIM_PIM2_ST	P38936	CDKN1A	Q9P1W9	PIM2	S153	I158M	158	Missense	distal	5	no	4.399	4.363	EPSD	COSMIC	4.322	Down-regulation
CAMK_PIM_PIM2_ST	P38936	CDKN1A	Q9P1W9	PIM2	S153	D149N	149	Missense	distal	-4	no	4.399	4.255	EPSD	COSMIC	4.322	Loss
CAMK_PIM_PIM2_ST	P38936	CDKN1A	Q9P1W9	PIM2	S153	R155C	155	Missense	proximal	2	no	4.399	4.637	EPSD	COSMIC	4.322	Up-regulation
CAMK_PIM_PIM2_ST	P35568	IRS1	Q9P1W9	PIM2	S189	R184C	184	Missense	distal	-5	no	4.580	1.572	EPSD	COSMIC	4.322	Loss
CAMK_PIM_PIM2_ST	P35568	IRS1	Q9P1W9	PIM2	S189	Y183C	183	Missense	distal	-6	no	4.580	4.676	EPSD	COSMIC	4.322	Up-regulation
CAMK_PIM_PIM2_ST	P35568	IRS1	Q9P1W9	PIM2	S189	L185F	185	Missense	distal	-4	no	4.580	4.758	EPSD	COSMIC	4.322	Up-regulation
CAMK_PIM_PIM2_ST	P35568	IRS1	Q9P1W9	PIM2	S189	K190N	190	Missense	proximal	1	no	4.580	4.781	EPSD	COSMIC	4.322	Up-regulation
CAMK_PIM_PIM2_ST	P35568	IRS1	Q9P1W9	PIM2	S189	S189N	189	Missense	central	0	yes	4.580	0.000	EPSD	COSMIC	4.322	Loss
CAMK_PIM_PIM2_ST	P35568	IRS1	Q9P1W9	PIM2	S193	K190N	190	Missense	distal	-3	no	5.012	4.275	EPSD	COSMIC	4.322	Loss
CAMK_PIM_PIM2_ST	P35568	IRS1	Q9P1W9	PIM2	S193	S189N	189	Missense	distal	-4	no	5.012	5.030	EPSD	COSMIC	4.322	Up-regulation
CAMK_PIM_PIM2_ST	P35568	IRS1	Q9P1W9	PIM2	S270	R265C	265	Missense	distal	-5	no	5.498	2.490	EPSD	COSMIC	4.322	Loss
CAMK_PIM_PIM2_ST	P35568	IRS1	Q9P1W9	PIM2	S270	S274P	274	Missense	distal	4	no	5.498	5.261	EPSD	COSMIC	4.322	Down-regulation
CAMK_PIM_PIM2_ST	P35568	IRS1	Q9P1W9	PIM2	S272	R265C	265	Missense	distal	-7	no	5.034	4.654	EPSD	COSMIC	4.322	Down-regulation
CAMK_PIM_PIM2_ST	P35568	IRS1	Q9P1W9	PIM2	S272	S274P	274	Missense	proximal	2	no	5.034	4.967	EPSD	COSMIC	4.322	Down-regulation
CAMK_PIM_PIM2_ST	P35568	IRS1	Q9P1W9	PIM2	S307	R301C	301	Missense	distal	-6	no	5.185	4.377	EPSD	COSMIC	4.322	Down-regulation
CAMK_PIM_PIM2_ST	P35568	IRS1	Q9P1W9	PIM2	S307	E306K	306	Missense	proximal	-1	no	5.185	4.804	EPSD	COSMIC	4.322	Down-regulation
CAMK_PIM_PIM2_ST	P35568	IRS1	Q9P1W9	PIM2	S307	A310T	310	Missense	distal	3	no	5.185	4.930	EPSD	COSMIC	4.322	Down-regulation
CAMK_PIM_PIM2_ST	P35568	IRS1	Q9P1W9	PIM2	S307	P313L	313	Missense	distal	6	no	5.185	5.081	EPSD	COSMIC;GDSC;CCLE	4.322	Down-regulation
CAMK_PIM_PIM2_ST	P35568	IRS1	Q9P1W9	PIM2	S307	R302L	302	Missense	distal	-5	no	5.185	2.978	EPSD	COSMIC	4.322	Loss
CAMK_PIM_PIM2_ST	P35568	IRS1	Q9P1W9	PIM2	S307	I308M	308	Missense	proximal	1	no	5.185	5.261	EPSD	COSMIC	4.322	Up-regulation
CAMK_PIM_PIM2_ST	P35568	IRS1	Q9P1W9	PIM2	S307	A310V	310	Missense	distal	3	no	5.185	4.900	EPSD	COSMIC	4.322	Down-regulation
CAMK_PIM_PIM2_ST	P35568	IRS1	Q9P1W9	PIM2	S312	E306K	306	Missense	distal	-6	no	5.068	5.118	EPSD	COSMIC	4.322	Up-regulation
CAMK_PIM_PIM2_ST	P35568	IRS1	Q9P1W9	PIM2	S312	A310T	310	Missense	proximal	-2	no	5.068	5.023	EPSD	COSMIC	4.322	Down-regulation
CAMK_PIM_PIM2_ST	P35568	IRS1	Q9P1W9	PIM2	S312	P313L	313	Missense	proximal	1	no	5.068	5.488	EPSD	COSMIC;GDSC;CCLE	4.322	Up-regulation
CAMK_PIM_PIM2_ST	P35568	IRS1	Q9P1W9	PIM2	S312	M316V	316	Missense	distal	4	no	5.068	4.713	EPSD	COSMIC	4.322	Down-regulation
CAMK_PIM_PIM2_ST	P35568	IRS1	Q9P1W9	PIM2	S312	M316I	316	Missense	distal	4	no	5.068	5.023	EPSD	COSMIC	4.322	Down-regulation
CAMK_PIM_PIM2_ST	P35568	IRS1	Q9P1W9	PIM2	S312	I308M	308	Missense	distal	-4	no	5.068	5.146	EPSD	COSMIC	4.322	Up-regulation
CAMK_PIM_PIM2_ST	P35568	IRS1	Q9P1W9	PIM2	S312	A310V	310	Missense	proximal	-2	no	5.068	4.725	EPSD	COSMIC	4.322	Down-regulation
CAMK_PIM_PIM2_ST	P35568	IRS1	Q9P1W9	PIM2	S330	F324L	324	Missense	distal	-6	no	4.131	4.374	EPSD	COSMIC	4.322	Gain
CAMK_PIM_PIM2_ST	P35568	IRS1	Q9P1W9	PIM2	T335	G332R	332	Missense	distal	-3	no	3.405	5.108	EPSD	COSMIC	4.322	Gain
CAMK_PIM_PIM2_ST	P35568	IRS1	Q9P1W9	PIM2	S337	G332R	332	Missense	distal	-5	no	1.738	5.074	EPSD	COSMIC	4.322	Gain
CAMK_PIM_PIM2_ST	P35568	IRS1	Q9P1W9	PIM2	S396	G401D	401	Missense	distal	5	no	4.297	4.367	EPSD	COSMIC	4.322	Gain
CAMK_PIM_PIM2_ST	P35568	IRS1	Q9P1W9	PIM2	S396	S395I	395	Missense	proximal	-1	no	4.297	4.371	EPSD	COSMIC;GDSC;CCLE	4.322	Gain
CAMK_PIM_PIM2_ST	P35568	IRS1	Q9P1W9	PIM2	S415	S415L	415	Missense	central	0	yes	5.097	0.000	EPSD	COSMIC	4.322	Loss
CAMK_PIM_PIM2_ST	P35568	IRS1	Q9P1W9	PIM2	S415	G418V	418	Missense	distal	3	no	5.097	5.144	EPSD	COSMIC;GDSC;CCLE	4.322	Up-regulation
CAMK_PIM_PIM2_ST	P35568	IRS1	Q9P1W9	PIM2	S415	D422N	422	Missense	distal	7	no	5.097	4.971	EPSD	COSMIC	4.322	Down-regulation
CAMK_PIM_PIM2_ST	P35568	IRS1	Q9P1W9	PIM2	S527	T530A	530	Missense	distal	3	no	4.512	4.767	EPSD	COSMIC	4.322	Up-regulation
CAMK_PIM_PIM2_ST	P35568	IRS1	Q9P1W9	PIM2	S527	R520L	520	Missense	distal	-7	no	4.512	4.082	EPSD	COSMIC	4.322	Loss
CAMK_PIM_PIM2_ST	P35568	IRS1	Q9P1W9	PIM2	S527	T533I	533	Missense	distal	6	no	4.512	4.588	EPSD	COSMIC	4.322	Up-regulation
CAMK_PIM_PIM2_ST	P35568	IRS1	Q9P1W9	PIM2	S527	F521I	521	Missense	distal	-6	no	4.512	4.552	EPSD	COSMIC	4.322	Up-regulation
CAMK_PIM_PIM2_ST	P35568	IRS1	Q9P1W9	PIM2	S527	H526Y	526	Missense	proximal	-1	no	4.512	4.039	EPSD	COSMIC	4.322	Loss
CAMK_PIM_PIM2_ST	P35568	IRS1	Q9P1W9	PIM2	S527	G529D	529	Missense	proximal	2	no	4.512	4.511	EPSD	COSMIC	4.322	Down-regulation
CAMK_PIM_PIM2_ST	P35568	IRS1	Q9P1W9	PIM2	T533	T530A	530	Missense	distal	-3	no	4.687	3.998	EPSD	COSMIC	4.322	Loss
CAMK_PIM_PIM2_ST	P35568	IRS1	Q9P1W9	PIM2	T533	T533I	533	Missense	central	0	yes	4.687	0.000	EPSD	COSMIC	4.322	Loss
CAMK_PIM_PIM2_ST	P35568	IRS1	Q9P1W9	PIM2	T533	H536N	536	Missense	distal	3	no	4.687	4.890	EPSD	COSMIC	4.322	Up-regulation
CAMK_PIM_PIM2_ST	P35568	IRS1	Q9P1W9	PIM2	T533	H526Y	526	Missense	distal	-7	no	4.687	4.621	EPSD	COSMIC	4.322	Down-regulation
CAMK_PIM_PIM2_ST	P35568	IRS1	Q9P1W9	PIM2	T533	G529D	529	Missense	distal	-4	no	4.687	4.858	EPSD	COSMIC	4.322	Up-regulation
CAMK_PIM_PIM2_ST	P35568	IRS1	Q9P1W9	PIM2	T533	T535A	535	Missense	proximal	2	no	4.687	4.691	EPSD	COSMIC	4.322	Up-regulation
CAMK_PIM_PIM2_ST	P35568	IRS1	Q9P1W9	PIM2	T533	Q537R	537	Missense	distal	4	no	4.687	4.489	EPSD	COSMIC	4.322	Down-regulation
CAMK_PIM_PIM2_ST	P35568	IRS1	Q9P1W9	PIM2	S603	H598R	598	Missense	distal	-5	no	3.447	5.894	EPSD	COSMIC	4.322	Gain
CAMK_PIM_PIM2_ST	P35568	IRS1	Q9P1W9	PIM2	S641	V640I	640	Missense	proximal	-1	no	4.990	4.451	EPSD	COSMIC;GDSC;CCLE	4.322	Down-regulation
CAMK_PIM_PIM2_ST	P35568	IRS1	Q9P1W9	PIM2	S641	A642T	642	Missense	proximal	1	no	4.990	4.993	EPSD	COSMIC	4.322	Up-regulation
CAMK_PIM_PIM2_ST	P35568	IRS1	Q9P1W9	PIM2	S736	D731G	731	Missense	distal	-5	no	4.364	4.297	EPSD	COSMIC	4.322	Loss
CAMK_PIM_PIM2_ST	P35568	IRS1	Q9P1W9	PIM2	S736	V738G	738	Missense	proximal	2	no	4.364	4.309	EPSD	COSMIC	4.322	Loss
CAMK_PIM_PIM2_ST	P35568	IRS1	Q9P1W9	PIM2	S736	G739E	739	Missense	distal	3	no	4.364	4.401	EPSD	COSMIC	4.322	Up-regulation
CAMK_PIM_PIM2_ST	P35568	IRS1	Q9P1W9	PIM2	S736	N734I	734	Missense	proximal	-2	no	4.364	4.483	EPSD	COSMIC	4.322	Up-regulation
CAMK_PIM_PIM2_ST	P35568	IRS1	Q9P1W9	PIM2	S736	N734K	734	Missense	proximal	-2	no	4.364	4.924	EPSD	COSMIC	4.322	Up-regulation
CAMK_PIM_PIM2_ST	P35568	IRS1	Q9P1W9	PIM2	T859	T859M	859	Missense	central	0	yes	5.482	0.000	EPSD	COSMIC	4.322	Loss
CAMK_PIM_PIM2_ST	P35568	IRS1	Q9P1W9	PIM2	T859	L855P	855	Missense	distal	-4	no	5.482	5.415	EPSD	COSMIC	4.322	Down-regulation
CAMK_PIM_PIM2_ST	P35568	IRS1	Q9P1W9	PIM2	T859	R857Q	857	Missense	proximal	-2	no	5.482	4.758	EPSD	COSMIC	4.322	Down-regulation
CAMK_PIM_PIM2_ST	P35568	IRS1	Q9P1W9	PIM2	T859	G864W	864	Missense	distal	5	no	5.482	5.518	EPSD	COSMIC	4.322	Up-regulation
CAMK_PIM_PIM2_ST	P35568	IRS1	Q9P1W9	PIM2	T859	R854L	854	Missense	distal	-5	no	5.482	3.275	EPSD	COSMIC	4.322	Loss
CAMK_PIM_PIM2_ST	P35568	IRS1	Q9P1W9	PIM2	T859	P858H	858	Missense	proximal	-1	no	5.482	5.874	EPSD	COSMIC	4.322	Up-regulation
CAMK_PIM_PIM2_ST	P35568	IRS1	Q9P1W9	PIM2	S918	V913L	913	Missense	distal	-5	no	4.143	5.809	EPSD	COSMIC	4.322	Gain
CAMK_PIM_PIM2_ST	P35568	IRS1	Q9P1W9	PIM2	T938	K943Q	943	Missense	distal	5	no	4.540	4.530	EPSD	COSMIC	4.322	Down-regulation
CAMK_PIM_PIM2_ST	P35568	IRS1	Q9P1W9	PIM2	T938	T936I	936	Missense	proximal	-2	no	4.540	4.529	EPSD	COSMIC	4.322	Down-regulation
CAMK_PIM_PIM2_ST	P35568	IRS1	Q9P1W9	PIM2	T938	R932I	932	Missense	distal	-6	no	4.540	3.677	EPSD	COSMIC	4.322	Loss
CAMK_PIM_PIM2_ST	P35568	IRS1	Q9P1W9	PIM2	S1011	S1011I	1011	Missense	central	0	yes	5.042	0.000	EPSD	COSMIC	4.322	Loss
CAMK_PIM_PIM2_ST	P35568	IRS1	Q9P1W9	PIM2	S1011	P1009S	1009	Missense	proximal	-2	no	5.042	5.187	EPSD	COSMIC	4.322	Up-regulation
CAMK_PIM_PIM2_ST	P35568	IRS1	Q9P1W9	PIM2	S1011	D1014G	1014	Missense	distal	3	no	5.042	4.967	EPSD	COSMIC	4.322	Down-regulation
CAMK_PIM_PIM2_ST	P35568	IRS1	Q9P1W9	PIM2	S1101	R1097W	1097	Missense	distal	-4	no	12.128	12.254	PhosphoSitePlus	COSMIC	4.322	Up-regulation
CAMK_PIM_PIM2_ST	P35568	IRS1	Q9P1W9	PIM2	S1101	E1102K	1102	Missense	proximal	1	no	12.128	11.575	PhosphoSitePlus	COSMIC	4.322	Down-regulation
CAMK_PIM_PIM2_ST	P35568	IRS1	Q9P1W9	PIM2	S1142	R1140C	1140	Missense	proximal	-2	no	4.575	3.666	EPSD	COSMIC;CCLE	4.322	Loss
CAMK_CAMK2_CAMK2A_ST	P24588	AKAP5	Q9UQM7	CAMK2A	S18	E15K	15	Missense	distal	-3	no	3.429	6.279	EPSD	COSMIC	4.810	Gain
CAMK_CAMK2_CAMK2A_ST	P24588	AKAP5	Q9UQM7	CAMK2A	S53	A46P	46	Missense	distal	-7	no	6.822	7.189	EPSD	COSMIC	4.810	Up-regulation
CAMK_CAMK2_CAMK2A_ST	Q14524	SCN5A	Q9UQM7	CAMK2A	S11	R14L	14	Missense	distal	3	no	7.285	7.067	EPSD;PhosphoSitePlus	COSMIC	4.810	Down-regulation
CAMK_CAMK2_CAMK2A_ST	Q14524	SCN5A	Q9UQM7	CAMK2A	S11	R18L	18	Missense	distal	7	no	7.285	7.344	EPSD;PhosphoSitePlus	COSMIC	4.810	Up-regulation
CAMK_CAMK2_CAMK2A_ST	Q14524	SCN5A	Q9UQM7	CAMK2A	S12	E19K	19	Missense	distal	7	no	5.341	5.551	EPSD;PhosphoSitePlus	COSMIC	4.810	Up-regulation
CAMK_CAMK2_CAMK2A_ST	Q14524	SCN5A	Q9UQM7	CAMK2A	S12	R14L	14	Missense	proximal	2	no	5.341	4.603	EPSD;PhosphoSitePlus	COSMIC	4.810	Loss
CAMK_CAMK2_CAMK2A_ST	Q14524	SCN5A	Q9UQM7	CAMK2A	S12	R18L	18	Missense	distal	6	no	5.341	5.224	EPSD;PhosphoSitePlus	COSMIC	4.810	Down-regulation
CAMK_CAMK2_CAMK2A_ST	Q14524	SCN5A	Q9UQM7	CAMK2A	T17	E19K	19	Missense	proximal	2	no	8.351	6.309	EPSD;PhosphoSitePlus	COSMIC	4.810	Down-regulation
CAMK_CAMK2_CAMK2A_ST	Q14524	SCN5A	Q9UQM7	CAMK2A	T17	R14L	14	Missense	distal	-3	no	8.351	3.229	EPSD;PhosphoSitePlus	COSMIC	4.810	Loss
CAMK_CAMK2_CAMK2A_ST	Q14524	SCN5A	Q9UQM7	CAMK2A	T17	R18L	18	Missense	proximal	1	no	8.351	8.829	EPSD;PhosphoSitePlus	COSMIC	4.810	Up-regulation
CAMK_CAMK2_CAMK2A_ST	Q14524	SCN5A	Q9UQM7	CAMK2A	T37	S42I	42	Missense	distal	5	no	5.348	5.079	EPSD	COSMIC	4.810	Down-regulation
CAMK_CAMK2_CAMK2A_ST	Q14524	SCN5A	Q9UQM7	CAMK2A	T37	G35S	35	Missense	proximal	-2	no	5.348	5.506	EPSD	COSMIC	4.810	Up-regulation
CAMK_CAMK2_CAMK2A_ST	Q14524	SCN5A	Q9UQM7	CAMK2A	S471	P468S	468	Missense	distal	-3	no	4.628	5.086	EPSD;PhosphoSitePlus	COSMIC	4.810	Gain
CAMK_CAMK2_CAMK2A_ST	Q14524	SCN5A	Q9UQM7	CAMK2A	S483	S476G	476	Missense	distal	-7	no	5.243	5.542	EPSD;PhosphoSitePlus	COSMIC	4.810	Up-regulation
CAMK_CAMK2_CAMK2A_ST	Q14524	SCN5A	Q9UQM7	CAMK2A	S499	E500Q	500	Missense	proximal	1	no	6.630	6.331	EPSD;PhosphoSitePlus	COSMIC	4.810	Down-regulation
CAMK_CAMK2_CAMK2A_ST	Q14524	SCN5A	Q9UQM7	CAMK2A	S499	K496N	496	Missense	distal	-3	no	6.630	4.064	EPSD;PhosphoSitePlus	COSMIC	4.810	Loss
CAMK_CAMK2_CAMK2A_ST	Q14524	SCN5A	Q9UQM7	CAMK2A	S499	G502S	502	Missense	distal	3	no	6.630	6.781	EPSD;PhosphoSitePlus	COSMIC	4.810	Up-regulation
CAMK_CAMK2_CAMK2A_ST	Q14524	SCN5A	Q9UQM7	CAMK2A	S499	D498Y	498	Missense	proximal	-1	no	6.630	6.673	EPSD;PhosphoSitePlus	COSMIC;GDSC;CCLE	4.810	Up-regulation
CAMK_CAMK2_CAMK2A_ST	Q14524	SCN5A	Q9UQM7	CAMK2A	S499	D498V	498	Missense	proximal	-1	no	6.630	6.641	EPSD;PhosphoSitePlus	COSMIC	4.810	Up-regulation
CAMK_CAMK2_CAMK2A_ST	Q14524	SCN5A	Q9UQM7	CAMK2A	S499	S497Y	497	Missense	proximal	-2	no	6.630	6.554	EPSD;PhosphoSitePlus	COSMIC	4.810	Down-regulation
CAMK_CAMK2_CAMK2A_ST	Q14524	SCN5A	Q9UQM7	CAMK2A	S499	R504G	504	Missense	distal	5	no	6.630	6.588	EPSD;PhosphoSitePlus	COSMIC	4.810	Down-regulation
CAMK_CAMK2_CAMK2A_ST	Q14524	SCN5A	Q9UQM7	CAMK2A	S499	D501Y	501	Missense	proximal	2	no	6.630	3.054	EPSD;PhosphoSitePlus	COSMIC	4.810	Loss
CAMK_CAMK2_CAMK2A_ST	Q14524	SCN5A	Q9UQM7	CAMK2A	S516	T518N	518	Missense	proximal	2	no	7.724	9.180	EPSD;PhosphoSitePlus	COSMIC	4.810	Up-regulation
CAMK_CAMK2_CAMK2A_ST	Q14524	SCN5A	Q9UQM7	CAMK2A	S516	R523C	523	Missense	distal	7	no	7.724	7.879	EPSD;PhosphoSitePlus	COSMIC	4.810	Up-regulation
CAMK_CAMK2_CAMK2A_ST	Q14524	SCN5A	Q9UQM7	CAMK2A	S524	T518N	518	Missense	distal	-6	no	5.646	5.678	EPSD	COSMIC	4.810	Up-regulation
CAMK_CAMK2_CAMK2A_ST	Q14524	SCN5A	Q9UQM7	CAMK2A	S524	T531P	531	Missense	distal	7	no	5.646	5.650	EPSD	COSMIC	4.810	Up-regulation
CAMK_CAMK2_CAMK2A_ST	Q14524	SCN5A	Q9UQM7	CAMK2A	S524	S525R	525	Missense	proximal	1	no	5.646	5.459	EPSD	COSMIC	4.810	Down-regulation
CAMK_CAMK2_CAMK2A_ST	Q14524	SCN5A	Q9UQM7	CAMK2A	S524	R523C	523	Missense	proximal	-1	no	5.646	5.318	EPSD	COSMIC	4.810	Down-regulation
CAMK_CAMK2_CAMK2A_ST	Q14524	SCN5A	Q9UQM7	CAMK2A	S528	S525R	525	Missense	distal	-3	no	1.475	5.935	EPSD;PhosphoSitePlus	COSMIC	4.810	Gain
CAMK_CAMK2_CAMK2A_ST	Q14524	SCN5A	Q9UQM7	CAMK2A	S571	P576S	576	Missense	distal	5	no	6.593	6.822	EPSD;PhosphoSitePlus	COSMIC	4.810	Up-regulation
CAMK_CAMK2_CAMK2A_ST	Q14524	SCN5A	Q9UQM7	CAMK2A	S571	W565R	565	Missense	distal	-6	no	6.593	6.315	EPSD;PhosphoSitePlus	COSMIC;GDSC;CCLE	4.810	Down-regulation
CAMK_CAMK2_CAMK2A_ST	Q14524	SCN5A	Q9UQM7	CAMK2A	S571	R569Q	569	Missense	proximal	-2	no	6.593	6.810	EPSD;PhosphoSitePlus	COSMIC	4.810	Up-regulation
CAMK_CAMK2_CAMK2A_ST	Q14524	SCN5A	Q9UQM7	CAMK2A	S581	P576S	576	Missense	distal	-5	no	4.885	4.884	EPSD	COSMIC	4.810	Down-regulation
CAMK_CAMK2_CAMK2A_ST	Q14524	SCN5A	Q9UQM7	CAMK2A	S581	G579E	579	Missense	proximal	-2	no	4.885	5.067	EPSD	COSMIC	4.810	Up-regulation
CAMK_CAMK2_CAMK2A_ST	Q14524	SCN5A	Q9UQM7	CAMK2A	S581	P583S	583	Missense	proximal	2	no	4.885	5.363	EPSD	COSMIC	4.810	Up-regulation
CAMK_CAMK2_CAMK2A_ST	Q14524	SCN5A	Q9UQM7	CAMK2A	S581	G579R	579	Missense	proximal	-2	no	4.885	5.114	EPSD	COSMIC	4.810	Up-regulation
CAMK_CAMK2_CAMK2A_ST	Q14524	SCN5A	Q9UQM7	CAMK2A	S581	A582T	582	Missense	proximal	1	no	4.885	4.984	EPSD	COSMIC	4.810	Up-regulation
CAMK_CAMK2_CAMK2A_ST	Q14524	SCN5A	Q9UQM7	CAMK2A	T594	K591N	591	Missense	distal	-3	no	7.816	5.250	EPSD	COSMIC;GDSC;CCLE	4.810	Down-regulation
CAMK_CAMK2_CAMK2A_ST	Q14524	SCN5A	Q9UQM7	CAMK2A	S664	A658T	658	Missense	distal	-6	no	7.191	7.375	EPSD;PhosphoSitePlus	COSMIC	4.810	Up-regulation
CAMK_CAMK2_CAMK2A_ST	Q14524	SCN5A	Q9UQM7	CAMK2A	S1083	G1085D	1085	Missense	proximal	2	no	4.159	5.994	EPSD	COSMIC	4.810	Gain
CAMK_CAMK2_CAMK2A_ST	Q14524	SCN5A	Q9UQM7	CAMK2A	S1503	K1499T	1499	Missense	distal	-4	no	4.989	4.767	EPSD;PhosphoSitePlus	COSMIC	4.810	Loss
CAMK_CAMK2_CAMK2A_ST	Q14524	SCN5A	Q9UQM7	CAMK2A	S1925	R1929H	1929	Missense	distal	4	no	5.284	5.396	EPSD;PhosphoSitePlus	COSMIC	4.810	Up-regulation
CAMK_CAMK2_CAMK2A_ST	Q14524	SCN5A	Q9UQM7	CAMK2A	S1925	A1924V	1924	Missense	proximal	-1	no	5.284	5.060	EPSD;PhosphoSitePlus	COSMIC	4.810	Down-regulation
CAMK_CAMK2_CAMK2A_ST	Q14524	SCN5A	Q9UQM7	CAMK2A	S1925	L1927F	1927	Missense	proximal	2	no	5.284	4.346	EPSD;PhosphoSitePlus	COSMIC	4.810	Loss
CAMK_CAMK2_CAMK2A_ST	Q14524	SCN5A	Q9UQM7	CAMK2A	S1985	T1984I	1984	Missense	proximal	-1	no	8.465	8.452	EPSD	COSMIC	4.810	Down-regulation
CAMK_CAMK2_CAMK2A_ST	Q14524	SCN5A	Q9UQM7	CAMK2A	S1985	L1988R	1988	Missense	distal	3	no	8.465	8.682	EPSD	COSMIC	4.810	Up-regulation
CAMK_CAMK2_CAMK2A_ST	Q14524	SCN5A	Q9UQM7	CAMK2A	S1985	A1983S	1983	Missense	proximal	-2	no	8.465	8.357	EPSD	COSMIC	4.810	Down-regulation
CAMK_CAMK2_CAMK2A_ST	Q14524	SCN5A	Q9UQM7	CAMK2A	S2007	F2004L	2004	Missense	distal	-3	no	-1.967	6.458	EPSD;PhosphoSitePlus	COSMIC;GDSC	4.810	Gain
CAMK_CAMK2_CAMK2A_ST	P35367	HRH1	Q9UQM7	CAMK2A	T142	L149M	149	Missense	distal	7	no	6.650	6.589	PhosphoSitePlus;EPSD	COSMIC	4.810	Down-regulation
CAMK_CAMK2_CAMK2A_ST	P35367	HRH1	Q9UQM7	CAMK2A	T142	R139H	139	Missense	distal	-3	no	6.650	1.153	PhosphoSitePlus;EPSD	COSMIC	4.810	Loss
CAMK_CAMK2_CAMK2A_ST	P35367	HRH1	Q9UQM7	CAMK2A	S277	G270E	270	Missense	distal	-7	no	5.238	4.950	EPSD	COSMIC	4.810	Down-regulation
CAMK_CAMK2_CAMK2A_ST	P35367	HRH1	Q9UQM7	CAMK2A	S277	E282K	282	Missense	distal	5	no	5.238	5.267	EPSD	COSMIC	4.810	Up-regulation
CAMK_CAMK2_CAMK2A_ST	P35367	HRH1	Q9UQM7	CAMK2A	S277	M283I	283	Missense	distal	6	no	5.238	5.185	EPSD	COSMIC	4.810	Down-regulation
CAMK_CAMK2_CAMK2A_ST	P35367	HRH1	Q9UQM7	CAMK2A	S285	E282K	282	Missense	distal	-3	no	2.426	5.276	EPSD	COSMIC	4.810	Gain
CAMK_CAMK2_CAMK2A_ST	P35367	HRH1	Q9UQM7	CAMK2A	S363	R360Q	360	Missense	distal	-3	no	6.631	3.060	EPSD	COSMIC	4.810	Loss
CAMK_CAMK2_CAMK2A_ST	P35367	HRH1	Q9UQM7	CAMK2A	S363	T369R	369	Missense	distal	6	no	6.631	6.680	EPSD	COSMIC	4.810	Up-regulation
CAMK_CAMK2_CAMK2A_ST	P35367	HRH1	Q9UQM7	CAMK2A	S363	T367A	367	Missense	distal	4	no	6.631	6.670	EPSD	COSMIC	4.810	Up-regulation
CAMK_CAMK2_CAMK2A_ST	P35367	HRH1	Q9UQM7	CAMK2A	S378	G383V	383	Missense	distal	5	no	5.588	5.604	EPSD	COSMIC	4.810	Up-regulation
CAMK_CAMK2_CAMK2A_ST	P35367	HRH1	Q9UQM7	CAMK2A	S378	D385E	385	Missense	distal	7	no	5.588	5.379	EPSD	COSMIC	4.810	Down-regulation
CAMK_CAMK2_CAMK2A_ST	P35367	HRH1	Q9UQM7	CAMK2A	S380	G383V	383	Missense	distal	3	no	6.421	6.549	EPSD	COSMIC	4.810	Up-regulation
CAMK_CAMK2_CAMK2A_ST	P35367	HRH1	Q9UQM7	CAMK2A	S380	D385E	385	Missense	distal	5	no	6.421	6.483	EPSD	COSMIC	4.810	Up-regulation
CAMK_CAMK2_CAMK2A_ST	P35367	HRH1	Q9UQM7	CAMK2A	S396	S396P	396	Missense	central	0	yes	7.356	0.000	EPSD;PhosphoSitePlus	COSMIC	4.810	Loss
CAMK_CAMK2_CAMK2A_ST	P35367	HRH1	Q9UQM7	CAMK2A	S396	S403F	403	Missense	distal	7	no	7.356	7.601	EPSD;PhosphoSitePlus	COSMIC	4.810	Up-regulation
CAMK_CAMK2_CAMK2A_ST	P35367	HRH1	Q9UQM7	CAMK2A	S396	R395S	395	Missense	proximal	-1	no	7.356	7.444	EPSD;PhosphoSitePlus	COSMIC	4.810	Up-regulation
CAMK_CAMK2_CAMK2A_ST	P35367	HRH1	Q9UQM7	CAMK2A	S396	R395L	395	Missense	proximal	-1	no	7.356	7.233	EPSD;PhosphoSitePlus	COSMIC	4.810	Down-regulation
CAMK_CAMK2_CAMK2A_ST	P35367	HRH1	Q9UQM7	CAMK2A	S398	G404R	404	Missense	distal	6	no	9.364	9.426	EPSD;PhosphoSitePlus	COSMIC	4.810	Up-regulation
CAMK_CAMK2_CAMK2A_ST	P35367	HRH1	Q9UQM7	CAMK2A	S398	S396P	396	Missense	proximal	-2	no	9.364	9.371	EPSD;PhosphoSitePlus	COSMIC	4.810	Up-regulation
CAMK_CAMK2_CAMK2A_ST	P35367	HRH1	Q9UQM7	CAMK2A	S398	S403F	403	Missense	distal	5	no	9.364	9.104	EPSD;PhosphoSitePlus	COSMIC	4.810	Down-regulation
CAMK_CAMK2_CAMK2A_ST	P35367	HRH1	Q9UQM7	CAMK2A	S398	R395S	395	Missense	distal	-3	no	9.364	4.904	EPSD;PhosphoSitePlus	COSMIC	4.810	Down-regulation
CAMK_CAMK2_CAMK2A_ST	P35367	HRH1	Q9UQM7	CAMK2A	S398	R395L	395	Missense	distal	-3	no	9.364	4.242	EPSD;PhosphoSitePlus	COSMIC	4.810	Loss
CAMK_CAMK2_CAMK2A_ST	P15036	ETS2	Q9UQM7	CAMK2A	S246	R243Q	243	Missense	distal	-3	no	8.446	4.874	EPSD;PhosphoSitePlus	COSMIC	4.810	Down-regulation
CAMK_CAMK2_CAMK2A_ST	P15036	ETS2	Q9UQM7	CAMK2A	S246	T250P	250	Missense	distal	4	no	8.446	8.365	EPSD;PhosphoSitePlus	COSMIC	4.810	Down-regulation
CAMK_CAMK2_CAMK2A_ST	P15036	ETS2	Q9UQM7	CAMK2A	S310	S313I	313	Missense	distal	3	no	6.673	6.428	PhosphoSitePlus;EPSD	COSMIC	4.810	Down-regulation
CAMK_CAMK2_CAMK2A_ST	P15036	ETS2	Q9UQM7	CAMK2A	S310	S310F	310	Missense	central	0	yes	6.673	0.000	PhosphoSitePlus;EPSD	COSMIC	4.810	Loss
CAMK_CAMK2_CAMK2A_ST	Q9Y618	NCOR2	Q9UQM7	CAMK2A	S140	G143D	143	Missense	distal	3	no	5.987	6.150	EPSD	COSMIC	4.810	Up-regulation
CAMK_CAMK2_CAMK2A_ST	Q9Y618	NCOR2	Q9UQM7	CAMK2A	S140	T142M	142	Missense	proximal	2	no	5.987	6.712	EPSD	COSMIC	4.810	Up-regulation
CAMK_CAMK2_CAMK2A_ST	Q9Y618	NCOR2	Q9UQM7	CAMK2A	S225	Q228H	228	Missense	distal	3	no	5.925	5.957	EPSD	COSMIC	4.810	Up-regulation
CAMK_CAMK2_CAMK2A_ST	Q9Y618	NCOR2	Q9UQM7	CAMK2A	S493	R488W	488	Missense	distal	-5	no	6.613	6.761	EPSD	COSMIC	4.810	Up-regulation
CAMK_CAMK2_CAMK2A_ST	Q9Y618	NCOR2	Q9UQM7	CAMK2A	S493	R490H	490	Missense	distal	-3	no	6.613	1.115	EPSD	COSMIC	4.810	Loss
CAMK_CAMK2_CAMK2A_ST	Q9Y618	NCOR2	Q9UQM7	CAMK2A	S493	R489H	489	Missense	distal	-4	no	6.613	6.489	EPSD	COSMIC	4.810	Down-regulation
CAMK_CAMK2_CAMK2A_ST	Q9Y618	NCOR2	Q9UQM7	CAMK2A	S493	Q498H	498	Missense	distal	5	no	6.613	6.727	EPSD	COSMIC	4.810	Up-regulation
CAMK_CAMK2_CAMK2A_ST	Q9Y618	NCOR2	Q9UQM7	CAMK2A	T550	D552N	552	Missense	proximal	2	no	5.344	4.334	EPSD	COSMIC	4.810	Loss
CAMK_CAMK2_CAMK2A_ST	Q9Y618	NCOR2	Q9UQM7	CAMK2A	T550	D551N	551	Missense	proximal	1	no	5.344	5.231	EPSD	COSMIC;CCLE	4.810	Down-regulation
CAMK_CAMK2_CAMK2A_ST	Q9Y618	NCOR2	Q9UQM7	CAMK2A	S585	R578C	578	Missense	distal	-7	no	4.581	5.249	EPSD	COSMIC	4.810	Gain
CAMK_CAMK2_CAMK2A_ST	Q9Y618	NCOR2	Q9UQM7	CAMK2A	S737	G734R	734	Missense	distal	-3	no	2.856	7.454	EPSD	COSMIC	4.810	Gain
CAMK_CAMK2_CAMK2A_ST	Q9Y618	NCOR2	Q9UQM7	CAMK2A	S745	A740V	740	Missense	distal	-5	no	5.729	5.607	EPSD	COSMIC	4.810	Down-regulation
CAMK_CAMK2_CAMK2A_ST	Q9Y618	NCOR2	Q9UQM7	CAMK2A	S745	S746P	746	Missense	proximal	1	no	5.729	5.362	EPSD	COSMIC	4.810	Down-regulation
CAMK_CAMK2_CAMK2A_ST	Q9Y618	NCOR2	Q9UQM7	CAMK2A	S939	G932A	932	Missense	distal	-7	no	7.929	7.393	EPSD	COSMIC	4.810	Down-regulation
CAMK_CAMK2_CAMK2A_ST	Q9Y618	NCOR2	Q9UQM7	CAMK2A	S1017	S1017N	1017	Missense	central	0	yes	4.945	0.000	EPSD	COSMIC	4.810	Loss
CAMK_CAMK2_CAMK2A_ST	Q9Y618	NCOR2	Q9UQM7	CAMK2A	S1017	P1015T	1015	Missense	proximal	-2	no	4.945	4.895	EPSD	COSMIC	4.810	Down-regulation
CAMK_CAMK2_CAMK2A_ST	Q9Y618	NCOR2	Q9UQM7	CAMK2A	S1017	A1011T	1011	Missense	distal	-6	no	4.945	5.130	EPSD	COSMIC;CCLE	4.810	Up-regulation
CAMK_CAMK2_CAMK2A_ST	Q9Y618	NCOR2	Q9UQM7	CAMK2A	S1023	P1028S	1028	Missense	distal	5	no	7.889	8.119	EPSD	COSMIC	4.810	Up-regulation
CAMK_CAMK2_CAMK2A_ST	Q9Y618	NCOR2	Q9UQM7	CAMK2A	S1023	S1017N	1017	Missense	distal	-6	no	7.889	7.991	EPSD	COSMIC	4.810	Up-regulation
CAMK_CAMK2_CAMK2A_ST	Q9Y618	NCOR2	Q9UQM7	CAMK2A	S1023	P1026L	1026	Missense	distal	3	no	7.889	7.849	EPSD	COSMIC	4.810	Down-regulation
CAMK_CAMK2_CAMK2A_ST	Q9Y618	NCOR2	Q9UQM7	CAMK2A	S1025	P1028S	1028	Missense	distal	3	no	5.954	6.225	EPSD	COSMIC	4.810	Up-regulation
CAMK_CAMK2_CAMK2A_ST	Q9Y618	NCOR2	Q9UQM7	CAMK2A	S1025	P1026L	1026	Missense	proximal	1	no	5.954	6.612	EPSD	COSMIC	4.810	Up-regulation
CAMK_CAMK2_CAMK2A_ST	Q9Y618	NCOR2	Q9UQM7	CAMK2A	S1227	T1223M	1223	Missense	distal	-4	no	5.683	5.740	EPSD	COSMIC	4.810	Up-regulation
CAMK_CAMK2_CAMK2A_ST	Q9Y618	NCOR2	Q9UQM7	CAMK2A	S1331	A1329V	1329	Missense	proximal	-2	no	6.695	6.277	EPSD	COSMIC	4.810	Down-regulation
CAMK_CAMK2_CAMK2A_ST	Q9Y618	NCOR2	Q9UQM7	CAMK2A	T1522	S1518W	1518	Missense	distal	-4	no	5.787	5.028	EPSD	COSMIC	4.810	Down-regulation
CAMK_CAMK2_CAMK2A_ST	Q9Y618	NCOR2	Q9UQM7	CAMK2A	T1522	S1529G	1529	Missense	distal	7	no	5.787	5.882	EPSD	COSMIC	4.810	Up-regulation
CAMK_CAMK2_CAMK2A_ST	Q9Y618	NCOR2	Q9UQM7	CAMK2A	T1522	S1529C	1529	Missense	distal	7	no	5.787	6.047	EPSD	COSMIC	4.810	Up-regulation
CAMK_CAMK2_CAMK2A_ST	Q9Y618	NCOR2	Q9UQM7	CAMK2A	T1522	A1523S	1523	Missense	proximal	1	no	5.787	6.005	EPSD	COSMIC	4.810	Up-regulation
CAMK_CAMK2_CAMK2A_ST	Q9Y618	NCOR2	Q9UQM7	CAMK2A	T1574	P1567L	1567	Missense	distal	-7	no	5.081	5.047	EPSD	COSMIC;CCLE	4.810	Down-regulation
CAMK_CAMK2_CAMK2A_ST	Q9Y618	NCOR2	Q9UQM7	CAMK2A	T1574	P1575T	1575	Missense	proximal	1	no	5.081	5.330	EPSD	COSMIC	4.810	Up-regulation
CAMK_CAMK2_CAMK2A_ST	Q9Y618	NCOR2	Q9UQM7	CAMK2A	T1574	P1573Q	1573	Missense	proximal	-1	no	5.081	5.423	EPSD	COSMIC	4.810	Up-regulation
CAMK_CAMK2_CAMK2A_ST	Q9Y618	NCOR2	Q9UQM7	CAMK2A	T1594	P1597H	1597	Missense	distal	3	no	5.024	5.255	EPSD	COSMIC	4.810	Up-regulation
CAMK_CAMK2_CAMK2A_ST	Q9Y618	NCOR2	Q9UQM7	CAMK2A	T1594	E1599D	1599	Missense	distal	5	no	5.024	4.962	EPSD	COSMIC	4.810	Down-regulation
CAMK_CAMK2_CAMK2A_ST	Q9Y618	NCOR2	Q9UQM7	CAMK2A	S1595	P1597H	1597	Missense	proximal	2	no	5.284	5.118	EPSD	COSMIC	4.810	Down-regulation
CAMK_CAMK2_CAMK2A_ST	Q9Y618	NCOR2	Q9UQM7	CAMK2A	S1595	E1599D	1599	Missense	distal	4	no	5.284	5.047	EPSD	COSMIC	4.810	Down-regulation
CAMK_CAMK2_CAMK2A_ST	Q9Y618	NCOR2	Q9UQM7	CAMK2A	S1722	R1719L	1719	Missense	distal	-3	no	8.971	3.848	EPSD	COSMIC	4.810	Loss
CAMK_CAMK2_CAMK2A_ST	Q9Y618	NCOR2	Q9UQM7	CAMK2A	S1722	S1726I	1726	Missense	distal	4	no	8.971	8.706	EPSD	COSMIC	4.810	Down-regulation
CAMK_CAMK2_CAMK2A_ST	Q9Y618	NCOR2	Q9UQM7	CAMK2A	S1722	S1727F	1727	Missense	distal	5	no	8.971	8.710	EPSD	COSMIC	4.810	Down-regulation
CAMK_CAMK2_CAMK2A_ST	Q9Y618	NCOR2	Q9UQM7	CAMK2A	S1727	L1730F	1730	Missense	distal	3	no	7.344	7.279	EPSD	COSMIC	4.810	Down-regulation
CAMK_CAMK2_CAMK2A_ST	Q9Y618	NCOR2	Q9UQM7	CAMK2A	S1727	S1726I	1726	Missense	proximal	-1	no	7.344	7.171	EPSD	COSMIC	4.810	Down-regulation
CAMK_CAMK2_CAMK2A_ST	Q9Y618	NCOR2	Q9UQM7	CAMK2A	S1727	S1727F	1727	Missense	central	0	yes	7.344	0.000	EPSD	COSMIC	4.810	Loss
CAMK_CAMK2_CAMK2A_ST	Q9Y618	NCOR2	Q9UQM7	CAMK2A	T1799	P1796R	1796	Missense	distal	-3	no	1.155	6.073	EPSD	COSMIC	4.810	Gain
CAMK_CAMK2_CAMK2A_ST	Q9Y618	NCOR2	Q9UQM7	CAMK2A	S1821	R1818S	1818	Missense	distal	-3	no	6.300	1.840	EPSD	COSMIC	4.810	Loss
CAMK_CAMK2_CAMK2A_ST	Q9Y618	NCOR2	Q9UQM7	CAMK2A	S1821	T1827N	1827	Missense	distal	6	no	6.300	6.346	EPSD	COSMIC	4.810	Up-regulation
CAMK_CAMK2_CAMK2A_ST	Q9Y618	NCOR2	Q9UQM7	CAMK2A	S2025	S2027C	2027	Missense	proximal	2	no	5.266	5.245	EPSD	COSMIC	4.810	Down-regulation
CAMK_CAMK2_CAMK2A_ST	Q9Y618	NCOR2	Q9UQM7	CAMK2A	S2025	S2027Y	2027	Missense	proximal	2	no	5.266	3.530	EPSD	COSMIC	4.810	Loss
CAMK_CAMK2_CAMK2A_ST	Q9Y618	NCOR2	Q9UQM7	CAMK2A	S2189	L2182F	2182	Missense	distal	-7	no	4.793	5.259	EPSD	COSMIC	4.810	Gain
CAMK_CAMK2_CAMK2A_ST	Q9Y618	NCOR2	Q9UQM7	CAMK2A	S2267	T2273I	2273	Missense	distal	6	no	6.877	6.834	EPSD	COSMIC	4.810	Down-regulation
CAMK_CAMK2_CAMK2A_ST	Q9Y618	NCOR2	Q9UQM7	CAMK2A	S2418	A2411V	2411	Missense	distal	-7	no	4.444	4.884	EPSD	COSMIC	4.810	Gain
CAMK_CAMK2_CAMK2A_ST	Q14654	KCNJ11	Q9UQM7	CAMK2A	T180	A178T	178	Missense	proximal	-2	no	7.115	6.965	PhosphoSitePlus;EPSD	COSMIC	4.810	Down-regulation
CAMK_CAMK2_CAMK2A_ST	Q14654	KCNJ11	Q9UQM7	CAMK2A	T180	A187V	187	Missense	distal	7	no	7.115	7.145	PhosphoSitePlus;EPSD	COSMIC	4.810	Up-regulation
CAMK_CAMK2_CAMK2A_ST	Q14654	KCNJ11	Q9UQM7	CAMK2A	T224	Q218K	218	Missense	distal	-6	no	5.257	5.282	EPSD;PhosphoSitePlus	COSMIC	4.810	Up-regulation
CAMK_CAMK2_CAMK2A_ST	Q14654	KCNJ11	Q9UQM7	CAMK2A	S372	P367S	367	Missense	distal	-5	no	9.838	9.836	EPSD	COSMIC	4.810	Down-regulation
CAMK_CAMK2_CAMK2A_ST	Q96PH1	NOX5	Q9UQM7	CAMK2A	S521	F522L	522	Missense	proximal	1	no	4.996	5.102	EPSD	COSMIC	4.810	Up-regulation
CAMK_CAMK2_CAMK2A_ST	Q96PH1	NOX5	Q9UQM7	CAMK2A	T540	S547L	547	Missense	distal	7	no	7.516	7.679	EPSD	COSMIC	4.810	Up-regulation
CAMK_CAMK2_CAMK2A_ST	Q96PH1	NOX5	Q9UQM7	CAMK2A	T540	R537S	537	Missense	distal	-3	no	7.516	3.056	EPSD	COSMIC	4.810	Loss
CAMK_CAMK2_CAMK2A_ST	Q96PH1	NOX5	Q9UQM7	CAMK2A	T540	M541I	541	Missense	proximal	1	no	7.516	7.614	EPSD	COSMIC	4.810	Up-regulation
CAMK_CAMK2_CAMK2A_ST	Q96PH1	NOX5	Q9UQM7	CAMK2A	T540	V539L	539	Missense	proximal	-1	no	7.516	7.475	EPSD	COSMIC	4.810	Down-regulation
CAMK_CAMK2_CAMK2A_ST	Q96PH1	NOX5	Q9UQM7	CAMK2A	T540	T540I	540	Missense	central	0	yes	7.516	0.000	EPSD	COSMIC	4.810	Loss
CAMK_CAMK2_CAMK2A_ST	Q96PH1	NOX5	Q9UQM7	CAMK2A	S544	M541I	541	Missense	distal	-3	no	4.550	5.096	EPSD	COSMIC	4.810	Gain
CAMK_CAMK2_CAMK2A_ST	Q96PH1	NOX5	Q9UQM7	CAMK2A	S705	I706T	706	Missense	proximal	1	no	5.518	5.057	EPSD	COSMIC	4.810	Down-regulation
CAMK_CAMK2_CAMK2A_ST	Q96PH1	NOX5	Q9UQM7	CAMK2A	S705	T711M	711	Missense	distal	6	no	5.518	5.528	EPSD	COSMIC	4.810	Up-regulation
CAMK_CAMK2_CAMK2A_ST	Q96PH1	NOX5	Q9UQM7	CAMK2A	S705	G708R	708	Missense	distal	3	no	5.518	5.574	EPSD	COSMIC	4.810	Up-regulation
CAMK_CAMK2_CAMK2A_ST	P05556	ITGB1	Q9UQM7	CAMK2A	S125	P128Q	128	Missense	distal	3	no	6.922	7.122	EPSD	COSMIC	4.810	Up-regulation
CAMK_CAMK2_CAMK2A_ST	P05556	ITGB1	Q9UQM7	CAMK2A	S178	R181K	181	Missense	distal	3	no	5.881	5.947	EPSD	COSMIC	4.810	Up-regulation
CAMK_CAMK2_CAMK2A_ST	P05556	ITGB1	Q9UQM7	CAMK2A	S593	D591N	591	Missense	proximal	-2	no	5.295	5.726	EPSD	COSMIC	4.810	Up-regulation
CAMK_CAMK2_CAMK2A_ST	P05556	ITGB1	Q9UQM7	CAMK2A	S597	A601T	601	Missense	distal	4	no	4.862	4.823	EPSD	COSMIC;GDSC;CCLE	4.810	Down-regulation
CAMK_CAMK2_CAMK2A_ST	P05556	ITGB1	Q9UQM7	CAMK2A	S597	G604R	604	Missense	distal	7	no	4.862	4.871	EPSD	COSMIC	4.810	Up-regulation
CAMK_CAMK2_CAMK2A_ST	P05556	ITGB1	Q9UQM7	CAMK2A	S597	D591N	591	Missense	distal	-6	no	4.862	4.884	EPSD	COSMIC	4.810	Up-regulation
CAMK_CAMK2_CAMK2A_ST	P07101	TH	Q9UQM7	CAMK2A	S19	R15S	15	Missense	distal	-4	no	10.486	10.555	EPSD;PhosphoSitePlus	COSMIC	4.810	Up-regulation
CAMK_CAMK2_CAMK2A_ST	P07101	TH	Q9UQM7	CAMK2A	S19	A17V	17	Missense	proximal	-2	no	10.486	10.069	EPSD;PhosphoSitePlus	COSMIC;CCLE	4.810	Down-regulation
CAMK_CAMK2_CAMK2A_ST	P07101	TH	Q9UQM7	CAMK2A	S19	S19C	19	Missense	central	0	yes	10.486	0.000	EPSD;PhosphoSitePlus	COSMIC;GDSC;CCLE	4.810	Loss
CAMK_CAMK2_CAMK2A_ST	P07101	TH	Q9UQM7	CAMK2A	S19	V18M	18	Missense	proximal	-1	no	10.486	10.648	EPSD;PhosphoSitePlus	COSMIC	4.810	Up-regulation
CAMK_CAMK2_CAMK2A_ST	P07101	TH	Q9UQM7	CAMK2A	S71	R64Q	64	Missense	distal	-7	no	9.735	9.792	EPSD;PhosphoSitePlus	COSMIC;CCLE	4.810	Up-regulation
CAMK_CAMK2_CAMK2A_ST	O15273	TCAP	Q9UQM7	CAMK2A	T109	R106C	106	Missense	distal	-3	no	5.609	0.029	EPSD	COSMIC	4.810	Loss
CAMK_CAMK2_CAMK2A_ST	O15273	TCAP	Q9UQM7	CAMK2A	T109	D108G	108	Missense	proximal	-1	no	5.609	5.644	EPSD	COSMIC	4.810	Up-regulation
CAMK_CAMK2_CAMK2A_ST	O15273	TCAP	Q9UQM7	CAMK2A	S157	A151E	151	Missense	distal	-6	no	9.266	9.264	PhosphoSitePlus;EPSD	COSMIC	4.810	Down-regulation
CAMK_CAMK2_CAMK2A_ST	O15273	TCAP	Q9UQM7	CAMK2A	S159	Q165H	165	Missense	distal	6	no	4.874	4.842	EPSD	COSMIC	4.810	Down-regulation
CAMK_CAMK2_CAMK2A_ST	O15273	TCAP	Q9UQM7	CAMK2A	S161	Q165H	165	Missense	distal	4	no	10.543	10.485	EPSD;PhosphoSitePlus	COSMIC	4.810	Down-regulation
CAMK_CAMK2_CAMK2A_ST	Q9UQM7	CAMK2A	Q9UQM7	CAMK2A	S314	K317T	317	Missense	distal	3	no	7.135	6.969	EPSD	COSMIC	4.810	Down-regulation
CAMK_CAMK2_CAMK2A_ST	Q9UQM7	CAMK2A	Q9UQM7	CAMK2A	S331	V327G	327	Missense	distal	-4	no	6.517	6.520	EPSD	COSMIC	4.810	Up-regulation
CAMK_CAMK2_CAMK2A_ST	Q9UQM7	CAMK2A	Q9UQM7	CAMK2A	S333	V327G	327	Missense	distal	-6	no	5.401	5.453	EPSD	COSMIC	4.810	Up-regulation
CAMK_CAMK2_CAMK2A_ST	P28329	CHAT	Q9UQM7	CAMK2A	S125	K122N	122	Missense	distal	-3	no	6.995	4.429	EPSD	COSMIC	4.810	Loss
CAMK_CAMK2_CAMK2A_ST	P28329	CHAT	Q9UQM7	CAMK2A	S125	A120T	120	Missense	distal	-5	no	6.995	6.986	EPSD	COSMIC	4.810	Down-regulation
CAMK_CAMK2_CAMK2A_ST	P28329	CHAT	Q9UQM7	CAMK2A	S125	A120G	120	Missense	distal	-5	no	6.995	7.024	EPSD	COSMIC	4.810	Up-regulation
CAMK_CAMK2_CAMK2A_ST	P28329	CHAT	Q9UQM7	CAMK2A	S125	E127D	127	Missense	proximal	2	no	6.995	7.912	EPSD	COSMIC	4.810	Up-regulation
CAMK_CAMK2_CAMK2A_ST	P28329	CHAT	Q9UQM7	CAMK2A	S125	S129Y	129	Missense	distal	4	no	6.995	6.911	EPSD	COSMIC	4.810	Down-regulation
CAMK_CAMK2_CAMK2A_ST	P28329	CHAT	Q9UQM7	CAMK2A	T373	K370R	370	Missense	distal	-3	no	3.155	5.423	EPSD	COSMIC	4.810	Gain
CAMK_CAMK2_CAMK2A_ST	P28329	CHAT	Q9UQM7	CAMK2A	S473	A479T	479	Missense	distal	6	no	8.060	7.971	EPSD	COSMIC	4.810	Down-regulation
CAMK_CAMK2_CAMK2A_ST	P28329	CHAT	Q9UQM7	CAMK2A	S473	R466Q	466	Missense	distal	-7	no	8.060	8.117	EPSD	COSMIC	4.810	Up-regulation
CAMK_CAMK2_CAMK2A_ST	P28329	CHAT	Q9UQM7	CAMK2A	S473	R466L	466	Missense	distal	-7	no	8.060	8.187	EPSD	COSMIC	4.810	Up-regulation
CAMK_CAMK2_CAMK2A_ST	P28329	CHAT	Q9UQM7	CAMK2A	S473	P478S	478	Missense	distal	5	no	8.060	8.290	EPSD	COSMIC	4.810	Up-regulation
CAMK_CAMK2_CAMK2A_ST	P28329	CHAT	Q9UQM7	CAMK2A	S473	S475G	475	Missense	proximal	2	no	8.060	8.066	EPSD	COSMIC	4.810	Up-regulation
CAMK_CAMK2_CAMK2A_ST	P28329	CHAT	Q9UQM7	CAMK2A	S558	E555K	555	Missense	distal	-3	no	3.391	6.242	EPSD	COSMIC	4.810	Gain
CAMK_CAMK2_CAMK2A_ST	P28329	CHAT	Q9UQM7	CAMK2A	T574	A577T	577	Missense	distal	3	no	5.843	5.607	EPSD	COSMIC	4.810	Down-regulation
CAMK_CAMK2_CAMK2A_ST	P28329	CHAT	Q9UQM7	CAMK2A	T574	V567M	567	Missense	distal	-7	no	5.843	5.613	EPSD	COSMIC;GDSC;CCLE	4.810	Down-regulation
CAMK_CAMK2_CAMK2A_ST	P28329	CHAT	Q9UQM7	CAMK2A	T574	T574I	574	Missense	central	0	yes	5.843	0.000	EPSD	COSMIC	4.810	Loss
CAMK_CAMK2_CAMK2A_ST	P28329	CHAT	Q9UQM7	CAMK2A	T574	V567A	567	Missense	distal	-7	no	5.843	5.403	EPSD	COSMIC	4.810	Down-regulation
CAMK_CAMK2_CAMK2A_ST	P28329	CHAT	Q9UQM7	CAMK2A	T574	P575S	575	Missense	proximal	1	no	5.843	6.210	EPSD	COSMIC	4.810	Up-regulation
CAMK_CAMK2_CAMK2A_ST	P28329	CHAT	Q9UQM7	CAMK2A	T574	R571K	571	Missense	distal	-3	no	5.843	3.575	EPSD	COSMIC	4.810	Loss
CAMK_CAMK2_CAMK2A_ST	P14921	ETS1	Q9UQM7	CAMK2A	S193	P190R	190	Missense	distal	-3	no	2.311	7.228	EPSD	COSMIC	4.810	Gain
CAMK_CAMK2_CAMK2A_ST	P14921	ETS1	Q9UQM7	CAMK2A	S254	S260G	260	Missense	distal	6	no	6.034	5.974	EPSD	COSMIC;CCLE	4.810	Down-regulation
CAMK_CAMK2_CAMK2A_ST	P14921	ETS1	Q9UQM7	CAMK2A	S254	Q249H	249	Missense	distal	-5	no	6.034	6.077	EPSD	COSMIC	4.810	Up-regulation
CAMK_CAMK2_CAMK2A_ST	P14921	ETS1	Q9UQM7	CAMK2A	S254	C261W	261	Missense	distal	7	no	6.034	6.194	EPSD	COSMIC	4.810	Up-regulation
CAMK_CAMK2_CAMK2A_ST	P14921	ETS1	Q9UQM7	CAMK2A	S257	R263H	263	Missense	distal	6	no	5.093	5.067	EPSD;PhosphoSitePlus	COSMIC	4.810	Down-regulation
CAMK_CAMK2_CAMK2A_ST	P14921	ETS1	Q9UQM7	CAMK2A	S257	S260G	260	Missense	distal	3	no	5.093	4.942	EPSD;PhosphoSitePlus	COSMIC;CCLE	4.810	Down-regulation
CAMK_CAMK2_CAMK2A_ST	P14921	ETS1	Q9UQM7	CAMK2A	S257	C261W	261	Missense	distal	4	no	5.093	4.993	EPSD;PhosphoSitePlus	COSMIC	4.810	Down-regulation
CAMK_CAMK2_CAMK2A_ST	P14921	ETS1	Q9UQM7	CAMK2A	S273	S267P	267	Missense	distal	-6	no	6.520	6.569	EPSD	COSMIC;CCLE	4.810	Up-regulation
CAMK_CAMK2_CAMK2A_ST	P14921	ETS1	Q9UQM7	CAMK2A	S273	W268L	268	Missense	distal	-5	no	6.520	6.351	EPSD	COSMIC	4.810	Down-regulation
CAMK_CAMK2_CAMK2A_ST	P14921	ETS1	Q9UQM7	CAMK2A	S273	R279H	279	Missense	distal	6	no	6.520	6.494	EPSD	COSMIC;CCLE	4.810	Down-regulation
CAMK_CAMK2_CAMK2A_ST	P14921	ETS1	Q9UQM7	CAMK2A	S273	Q278K	278	Missense	distal	5	no	6.520	6.629	EPSD	COSMIC	4.810	Up-regulation
CAMK_CAMK2_CAMK2A_ST	P14921	ETS1	Q9UQM7	CAMK2A	S273	L277R	277	Missense	distal	4	no	6.520	6.558	EPSD	COSMIC	4.810	Up-regulation
CAMK_CAMK2_CAMK2A_ST	P14921	ETS1	Q9UQM7	CAMK2A	S273	R279C	279	Missense	distal	6	no	6.520	6.355	EPSD	COSMIC	4.810	Down-regulation
CAMK_CAMK2_CAMK2A_ST	P14921	ETS1	Q9UQM7	CAMK2A	S273	F274L	274	Missense	proximal	1	no	6.520	6.626	EPSD	COSMIC	4.810	Up-regulation
CAMK_CAMK2_CAMK2A_ST	P14921	ETS1	Q9UQM7	CAMK2A	S276	F274L	274	Missense	proximal	-2	no	4.255	4.938	EPSD	COSMIC	4.810	Gain
CAMK_CAMK2_CAMK2A_ST	P14921	ETS1	Q9UQM7	CAMK2A	S282	D287N	287	Missense	distal	5	no	9.486	9.497	EPSD;PhosphoSitePlus	COSMIC	4.810	Up-regulation
CAMK_CAMK2_CAMK2A_ST	P14921	ETS1	Q9UQM7	CAMK2A	S282	R279H	279	Missense	distal	-3	no	9.486	3.989	EPSD;PhosphoSitePlus	COSMIC;CCLE	4.810	Loss
CAMK_CAMK2_CAMK2A_ST	P14921	ETS1	Q9UQM7	CAMK2A	S282	Q278K	278	Missense	distal	-4	no	9.486	9.600	EPSD;PhosphoSitePlus	COSMIC	4.810	Up-regulation
CAMK_CAMK2_CAMK2A_ST	P14921	ETS1	Q9UQM7	CAMK2A	S282	L277R	277	Missense	distal	-5	no	9.486	9.506	EPSD;PhosphoSitePlus	COSMIC	4.810	Up-regulation
CAMK_CAMK2_CAMK2A_ST	P14921	ETS1	Q9UQM7	CAMK2A	S282	R279C	279	Missense	distal	-3	no	9.486	3.905	EPSD;PhosphoSitePlus	COSMIC	4.810	Loss
CAMK_CAMK2_CAMK2A_ST	P14921	ETS1	Q9UQM7	CAMK2A	S285	D287N	287	Missense	proximal	2	no	6.022	5.012	PhosphoSitePlus;EPSD	COSMIC	4.810	Down-regulation
CAMK_CAMK2_CAMK2A_ST	P14921	ETS1	Q9UQM7	CAMK2A	S285	R279H	279	Missense	distal	-6	no	6.022	5.976	PhosphoSitePlus;EPSD	COSMIC;CCLE	4.810	Down-regulation
CAMK_CAMK2_CAMK2A_ST	P14921	ETS1	Q9UQM7	CAMK2A	S285	Q278K	278	Missense	distal	-7	no	6.022	5.900	PhosphoSitePlus;EPSD	COSMIC	4.810	Down-regulation
CAMK_CAMK2_CAMK2A_ST	P14921	ETS1	Q9UQM7	CAMK2A	S285	R279C	279	Missense	distal	-6	no	6.022	6.217	PhosphoSitePlus;EPSD	COSMIC	4.810	Up-regulation
CAMK_CAMK2_CAMK2A_ST	P35270	SPR	Q9UQM7	CAMK2A	S16	T13S	13	Missense	distal	-3	no	5.348	5.944	EPSD	COSMIC	4.810	Up-regulation
CAMK_CAMK2_CAMK2A_ST	P35270	SPR	Q9UQM7	CAMK2A	S243	K247R	247	Missense	distal	4	no	6.278	6.153	EPSD	COSMIC	4.810	Down-regulation
CAMK_CAMK2_CAMK2A_ST	P43003	SLC1A3	Q9UQM7	CAMK2A	T26	A29V	29	Missense	distal	3	no	7.224	7.162	PhosphoSitePlus;EPSD	COSMIC	4.810	Down-regulation
CAMK_CAMK2_CAMK2A_ST	P43003	SLC1A3	Q9UQM7	CAMK2A	T26	R25H	25	Missense	proximal	-1	no	7.224	7.370	PhosphoSitePlus;EPSD	COSMIC	4.810	Up-regulation
CAMK_CAMK2_CAMK2A_ST	P43003	SLC1A3	Q9UQM7	CAMK2A	T26	R23C	23	Missense	distal	-3	no	7.224	1.643	PhosphoSitePlus;EPSD	COSMIC	4.810	Loss
CAMK_CAMK2_CAMK2A_ST	P43003	SLC1A3	Q9UQM7	CAMK2A	S82	P84S	84	Missense	proximal	2	no	4.378	4.856	EPSD	COSMIC	4.810	Gain
CAMK_CAMK2_CAMK2A_ST	Q15796	SMAD2	Q9UQM7	CAMK2A	S47	K53E	53	Missense	distal	6	no	5.417	5.469	EPSD	COSMIC	4.810	Up-regulation
CAMK_CAMK2_CAMK2A_ST	Q15796	SMAD2	Q9UQM7	CAMK2A	S47	W40G	40	Missense	distal	-7	no	5.417	5.005	EPSD	COSMIC	4.810	Down-regulation
CAMK_CAMK2_CAMK2A_ST	Q15796	SMAD2	Q9UQM7	CAMK2A	S47	A44T	44	Missense	distal	-3	no	5.417	4.781	EPSD	COSMIC	4.810	Loss
CAMK_CAMK2_CAMK2A_ST	Q15796	SMAD2	Q9UQM7	CAMK2A	S47	K54T	54	Missense	distal	7	no	5.417	5.445	EPSD	COSMIC	4.810	Up-regulation
CAMK_CAMK2_CAMK2A_ST	Q15796	SMAD2	Q9UQM7	CAMK2A	S47	E42Q	42	Missense	distal	-5	no	5.417	5.362	EPSD	COSMIC	4.810	Down-regulation
CAMK_CAMK2_CAMK2A_ST	Q15796	SMAD2	Q9UQM7	CAMK2A	S110	R114C	114	Missense	distal	4	no	6.202	6.010	EPSD;PhosphoSitePlus	COSMIC	4.810	Down-regulation
CAMK_CAMK2_CAMK2A_ST	Q15796	SMAD2	Q9UQM7	CAMK2A	S240	D242E	242	Missense	proximal	2	no	4.917	4.001	EPSD;PhosphoSitePlus	COSMIC	4.810	Loss
CAMK_CAMK2_CAMK2A_ST	Q15796	SMAD2	Q9UQM7	CAMK2A	S240	S245C	245	Missense	distal	5	no	4.917	4.483	EPSD;PhosphoSitePlus	COSMIC	4.810	Loss
CAMK_CAMK2_CAMK2A_ST	Q15796	SMAD2	Q9UQM7	CAMK2A	S240	P246L	246	Missense	distal	6	no	4.917	4.886	EPSD;PhosphoSitePlus	COSMIC	4.810	Down-regulation
CAMK_CAMK2_CAMK2A_ST	Q15796	SMAD2	Q9UQM7	CAMK2A	S240	S240R	240	Missense	central	0	yes	4.917	0.000	EPSD;PhosphoSitePlus	COSMIC	4.810	Loss
CAMK_CAMK2_CAMK2A_ST	Q15796	SMAD2	Q9UQM7	CAMK2A	T243	S240R	240	Missense	distal	-3	no	0.815	5.275	EPSD	COSMIC	4.810	Gain
CAMK_CAMK2_CAMK2A_ST	Q15796	SMAD2	Q9UQM7	CAMK2A	S260	S255F	255	Missense	distal	-5	no	5.329	5.346	PhosphoSitePlus;EPSD	COSMIC	4.810	Up-regulation
CAMK_CAMK2_CAMK2A_ST	Q15796	SMAD2	Q9UQM7	CAMK2A	S260	P265H	265	Missense	distal	5	no	5.329	5.531	PhosphoSitePlus;EPSD	COSMIC	4.810	Up-regulation
CAMK_CAMK2_CAMK2A_ST	Q15796	SMAD2	Q9UQM7	CAMK2A	S260	Q264E	264	Missense	distal	4	no	5.329	5.460	PhosphoSitePlus;EPSD	COSMIC	4.810	Up-regulation
CAMK_CAMK2_CAMK2A_ST	Q15796	SMAD2	Q9UQM7	CAMK2A	T324	N320K	320	Missense	distal	-4	no	5.120	5.222	EPSD	COSMIC	4.810	Up-regulation
CAMK_CAMK2_CAMK2A_ST	Q15796	SMAD2	Q9UQM7	CAMK2A	T324	R329K	329	Missense	distal	5	no	5.120	5.228	EPSD	COSMIC	4.810	Up-regulation
CAMK_CAMK2_CAMK2A_ST	Q15796	SMAD2	Q9UQM7	CAMK2A	T324	V319L	319	Missense	distal	-5	no	5.120	5.143	EPSD	COSMIC	4.810	Up-regulation
CAMK_CAMK2_CAMK2A_ST	Q15796	SMAD2	Q9UQM7	CAMK2A	T324	V319A	319	Missense	distal	-5	no	5.120	5.241	EPSD	COSMIC	4.810	Up-regulation
CAMK_CAMK2_CAMK2A_ST	Q15796	SMAD2	Q9UQM7	CAMK2A	T324	N320I	320	Missense	distal	-4	no	5.120	4.903	EPSD	COSMIC	4.810	Down-regulation
CAMK_CAMK2_CAMK2A_ST	Q15796	SMAD2	Q9UQM7	CAMK2A	T324	R330S	330	Missense	distal	6	no	5.120	5.118	EPSD	COSMIC	4.810	Down-regulation
CAMK_CAMK2_CAMK2A_ST	Q15796	SMAD2	Q9UQM7	CAMK2A	T324	V319D	319	Missense	distal	-5	no	5.120	5.286	EPSD	COSMIC	4.810	Up-regulation
CAMK_CAMK2_CAMK2A_ST	Q15796	SMAD2	Q9UQM7	CAMK2A	T430	S433N	433	Missense	distal	3	no	6.049	5.935	EPSD	COSMIC	4.810	Down-regulation
CAMK_CAMK2_CAMK2A_ST	Q15796	SMAD2	Q9UQM7	CAMK2A	T430	V431A	431	Missense	proximal	1	no	6.049	5.697	EPSD	COSMIC	4.810	Down-regulation
CAMK_CAMK2_CAMK2A_ST	Q15796	SMAD2	Q9UQM7	CAMK2A	T430	T432I	432	Missense	proximal	2	no	6.049	6.605	EPSD	COSMIC	4.810	Up-regulation
CAMK_CAMK2_CAMK2A_ST	Q15796	SMAD2	Q9UQM7	CAMK2A	T430	R427Q	427	Missense	distal	-3	no	6.049	2.478	EPSD	COSMIC	4.810	Loss
CAMK_CAMK2_CAMK2A_ST	Q15796	SMAD2	Q9UQM7	CAMK2A	T430	S433R	433	Missense	distal	3	no	6.049	5.954	EPSD	COSMIC	4.810	Down-regulation
CAMK_CAMK2_CAMK2A_ST	Q15796	SMAD2	Q9UQM7	CAMK2A	T430	T430M	430	Missense	central	0	yes	6.049	0.000	EPSD	COSMIC	4.810	Loss
CAMK_CAMK2_CAMK2A_ST	Q15796	SMAD2	Q9UQM7	CAMK2A	T430	C436W	436	Missense	distal	6	no	6.049	5.976	EPSD	COSMIC	4.810	Down-regulation
CAMK_CAMK2_CAMK2A_ST	Q15796	SMAD2	Q9UQM7	CAMK2A	S460	G457R	457	Missense	distal	-3	no	2.455	7.053	EPSD	COSMIC	4.810	Gain
CAMK_CAMK2_CAMK2A_ST	Q15796	SMAD2	Q9UQM7	CAMK2A	S465	R462C	462	Missense	distal	-3	no	7.825	2.245	EPSD	COSMIC;GDSC;CCLE	4.810	Loss
CAMK_CAMK2_CAMK2A_ST	Q15796	SMAD2	Q9UQM7	CAMK2A	S465	C463F	463	Missense	proximal	-2	no	7.825	7.772	EPSD	COSMIC	4.810	Down-regulation
CAMK_CAMK2_CAMK2A_ST	Q15796	SMAD2	Q9UQM7	CAMK2A	S465	S465I	465	Missense	central	0	yes	7.825	0.000	EPSD	COSMIC	4.810	Loss
CAMK_CAMK2_CAMK2A_ST	Q15796	SMAD2	Q9UQM7	CAMK2A	S465	C463Y	463	Missense	proximal	-2	no	7.825	8.481	EPSD	COSMIC	4.810	Up-regulation
CAMK_CAMK2_CAMK2A_ST	Q15796	SMAD2	Q9UQM7	CAMK2A	S465	S465N	465	Missense	central	0	yes	7.825	0.000	EPSD	COSMIC;GDSC;CCLE	4.810	Loss
CAMK_CAMK2_CAMK2A_ST	Q15796	SMAD2	Q9UQM7	CAMK2A	S465	P459H	459	Missense	distal	-6	no	7.825	7.685	EPSD	COSMIC	4.810	Down-regulation
CAMK_CAMK2_CAMK2A_ST	Q15796	SMAD2	Q9UQM7	CAMK2A	S465	S465R	465	Missense	central	0	yes	7.825	0.000	EPSD	COSMIC	4.810	Loss
CAMK_CAMK2_CAMK2A_ST	Q15796	SMAD2	Q9UQM7	CAMK2A	S465	S464L	464	Missense	proximal	-1	no	7.825	7.615	EPSD	COSMIC	4.810	Down-regulation
CAMK_CAMK2_CAMK2A_ST	P46527	CDKN1B	Q9UQM7	CAMK2A	S12	R5L	5	Missense	distal	-7	no	4.883	5.010	EPSD	COSMIC	4.810	Up-regulation
CAMK_CAMK2_CAMK2A_ST	P46527	CDKN1B	Q9UQM7	CAMK2A	S12	E14K	14	Missense	proximal	2	no	4.883	2.842	EPSD	COSMIC	4.810	Loss
CAMK_CAMK2_CAMK2A_ST	P46527	CDKN1B	Q9UQM7	CAMK2A	S12	M16T	16	Missense	distal	4	no	4.883	4.919	EPSD	COSMIC	4.810	Up-regulation
CAMK_CAMK2_CAMK2A_ST	P46527	CDKN1B	Q9UQM7	CAMK2A	S12	P11S	11	Missense	proximal	-1	no	4.883	5.069	EPSD	COSMIC	4.810	Up-regulation
CAMK_CAMK2_CAMK2A_ST	P46527	CDKN1B	Q9UQM7	CAMK2A	S12	A18V	18	Missense	distal	6	no	4.883	4.720	EPSD	COSMIC	4.810	Loss
CAMK_CAMK2_CAMK2A_ST	P46527	CDKN1B	Q9UQM7	CAMK2A	S12	S12N	12	Missense	central	0	yes	4.883	0.000	EPSD	COSMIC	4.810	Loss
CAMK_CAMK2_CAMK2A_ST	P46527	CDKN1B	Q9UQM7	CAMK2A	S12	D17E	17	Missense	distal	5	no	4.883	4.945	EPSD	COSMIC	4.810	Up-regulation
CAMK_CAMK2_CAMK2A_ST	P46527	CDKN1B	Q9UQM7	CAMK2A	S83	E80Q	80	Missense	distal	-3	no	3.472	5.019	EPSD	COSMIC	4.810	Gain
CAMK_CAMK2_CAMK2A_ST	P46527	CDKN1B	Q9UQM7	CAMK2A	S106	Q107R	107	Missense	proximal	1	no	5.959	5.986	EPSD	COSMIC	4.810	Up-regulation
CAMK_CAMK2_CAMK2A_ST	P46527	CDKN1B	Q9UQM7	CAMK2A	S106	D108N	108	Missense	proximal	2	no	5.959	4.948	EPSD	COSMIC	4.810	Down-regulation
CAMK_CAMK2_CAMK2A_ST	P46527	CDKN1B	Q9UQM7	CAMK2A	S110	Q107R	107	Missense	distal	-3	no	2.373	5.944	EPSD	COSMIC	4.810	Gain
CAMK_CAMK2_CAMK2A_ST	P46527	CDKN1B	Q9UQM7	CAMK2A	T157	A156V	156	Missense	proximal	-1	no	8.037	7.813	EPSD	COSMIC	4.810	Down-regulation
CAMK_CAMK2_CAMK2A_ST	P46527	CDKN1B	Q9UQM7	CAMK2A	T157	D158Y	158	Missense	proximal	1	no	8.037	8.364	EPSD	COSMIC	4.810	Up-regulation
CAMK_CAMK2_CAMK2A_ST	P46527	CDKN1B	Q9UQM7	CAMK2A	T157	T157N	157	Missense	central	0	yes	8.037	0.000	EPSD	COSMIC	4.810	Loss
CAMK_CAMK2_CAMK2A_ST	P46527	CDKN1B	Q9UQM7	CAMK2A	T157	D159Y	159	Missense	proximal	2	no	8.037	4.460	EPSD	COSMIC	4.810	Loss
CAMK_CAMK2_CAMK2A_ST	P46527	CDKN1B	Q9UQM7	CAMK2A	T157	S161F	161	Missense	distal	4	no	8.037	7.879	EPSD	COSMIC	4.810	Down-regulation
CAMK_CAMK2_CAMK2A_ST	P46527	CDKN1B	Q9UQM7	CAMK2A	S175	R169K	169	Missense	distal	-6	no	5.426	5.454	EPSD	COSMIC	4.810	Up-regulation
CAMK_CAMK2_CAMK2A_ST	P46527	CDKN1B	Q9UQM7	CAMK2A	S175	N168K	168	Missense	distal	-7	no	5.426	5.232	EPSD	COSMIC	4.810	Down-regulation
CAMK_CAMK2_CAMK2A_ST	P46527	CDKN1B	Q9UQM7	CAMK2A	S175	G182D	182	Missense	distal	7	no	5.426	5.396	EPSD	COSMIC	4.810	Down-regulation
CAMK_CAMK2_CAMK2A_ST	P46527	CDKN1B	Q9UQM7	CAMK2A	S183	V184L	184	Missense	proximal	1	no	5.521	5.678	EPSD	COSMIC	4.810	Up-regulation
CAMK_CAMK2_CAMK2A_ST	P46527	CDKN1B	Q9UQM7	CAMK2A	S183	G182D	182	Missense	proximal	-1	no	5.521	5.487	EPSD	COSMIC	4.810	Down-regulation
CAMK_CAMK2_CAMK2A_ST	P46527	CDKN1B	Q9UQM7	CAMK2A	T198	R194K	194	Missense	distal	-4	no	5.696	5.705	EPSD	COSMIC	4.810	Up-regulation
CAMK_CAMK2_CAMK2A_ST	P11831	SRF	Q9UQM7	CAMK2A	S372	P366T	366	Missense	distal	-6	no	4.910	4.931	EPSD	COSMIC;GDSC;CCLE	4.810	Up-regulation
CAMK_CAMK2_CAMK2A_ST	P11831	SRF	Q9UQM7	CAMK2A	S372	R373H	373	Missense	proximal	1	no	4.910	5.423	EPSD	COSMIC	4.810	Up-regulation
CAMK_CAMK2_CAMK2A_ST	P11831	SRF	Q9UQM7	CAMK2A	S372	D378G	378	Missense	distal	6	no	4.910	4.821	EPSD	COSMIC	4.810	Down-regulation
CAMK_CAMK2_CAMK2A_ST	P11831	SRF	Q9UQM7	CAMK2A	S372	R373S	373	Missense	proximal	1	no	4.910	5.097	EPSD	COSMIC	4.810	Up-regulation
CAMK_CAMK2_CAMK2A_ST	P11831	SRF	Q9UQM7	CAMK2A	S372	A369V	369	Missense	distal	-3	no	4.910	4.208	EPSD	COSMIC	4.810	Loss
CAMK_CAMK2_CAMK2A_ST	P11831	SRF	Q9UQM7	CAMK2A	S372	S375N	375	Missense	distal	3	no	4.910	4.796	EPSD	COSMIC	4.810	Loss
CAMK_CAMK2_CAMK2A_ST	Q9NQC7	CYLD	Q9UQM7	CAMK2A	S62	P61H	61	Missense	proximal	-1	no	7.149	7.393	EPSD	COSMIC	4.810	Up-regulation
CAMK_CAMK2_CAMK2A_ST	Q9NQC7	CYLD	Q9UQM7	CAMK2A	S62	R59M	59	Missense	distal	-3	no	7.149	2.332	EPSD	COSMIC	4.810	Loss
CAMK_CAMK2_CAMK2A_ST	Q9NQC7	CYLD	Q9UQM7	CAMK2A	S352	R351I	351	Missense	proximal	-1	no	6.913	6.827	EPSD	COSMIC;GDSC;CCLE	4.810	Down-regulation
CAMK_CAMK2_CAMK2A_ST	Q9NQC7	CYLD	Q9UQM7	CAMK2A	S352	N350D	350	Missense	proximal	-2	no	6.913	6.481	EPSD	COSMIC	4.810	Down-regulation
CAMK_CAMK2_CAMK2A_ST	Q9NQC7	CYLD	Q9UQM7	CAMK2A	S361	G360L	360	Missense	proximal	-1	no	4.844	4.779	EPSD	COSMIC	4.810	Loss
CAMK_CAMK2_CAMK2A_ST	Q9NQC7	CYLD	Q9UQM7	CAMK2A	S361	S365L	365	Missense	distal	4	no	4.844	4.633	EPSD	COSMIC	4.810	Loss
CAMK_CAMK2_CAMK2A_ST	Q9NQC7	CYLD	Q9UQM7	CAMK2A	S361	P367S	367	Missense	distal	6	no	4.844	4.927	EPSD	COSMIC	4.810	Up-regulation
CAMK_CAMK2_CAMK2A_ST	Q9NQC7	CYLD	Q9UQM7	CAMK2A	S361	S362L	362	Missense	proximal	1	no	4.844	5.135	EPSD	COSMIC	4.810	Up-regulation
CAMK_CAMK2_CAMK2A_ST	Q9NQC7	CYLD	Q9UQM7	CAMK2A	S362	G360L	360	Missense	proximal	-2	no	5.998	6.053	PhosphoSitePlus;EPSD	COSMIC	4.810	Up-regulation
CAMK_CAMK2_CAMK2A_ST	Q9NQC7	CYLD	Q9UQM7	CAMK2A	S362	S365L	365	Missense	distal	3	no	5.998	5.686	PhosphoSitePlus;EPSD	COSMIC	4.810	Down-regulation
CAMK_CAMK2_CAMK2A_ST	Q9NQC7	CYLD	Q9UQM7	CAMK2A	S362	P367S	367	Missense	distal	5	no	5.998	6.228	PhosphoSitePlus;EPSD	COSMIC	4.810	Up-regulation
CAMK_CAMK2_CAMK2A_ST	Q9NQC7	CYLD	Q9UQM7	CAMK2A	S362	S362L	362	Missense	central	0	yes	5.998	0.000	PhosphoSitePlus;EPSD	COSMIC	4.810	Loss
CAMK_CAMK2_CAMK2A_ST	Q9NQC7	CYLD	Q9UQM7	CAMK2A	S418	E413K	413	Missense	distal	-5	no	5.712	5.709	EPSD;PhosphoSitePlus	COSMIC	4.810	Down-regulation
CAMK_CAMK2_CAMK2A_ST	Q9NQC7	CYLD	Q9UQM7	CAMK2A	S418	N414S	414	Missense	distal	-4	no	5.712	5.874	EPSD;PhosphoSitePlus	COSMIC	4.810	Up-regulation
CAMK_CAMK2_CAMK2A_ST	Q9NQC7	CYLD	Q9UQM7	CAMK2A	S444	Q443K	443	Missense	proximal	-1	no	5.317	5.223	EPSD	COSMIC	4.810	Down-regulation
CAMK_CAMK2_CAMK2A_ST	Q9NQC7	CYLD	Q9UQM7	CAMK2A	S547	S547L	547	Missense	central	0	yes	6.832	0.000	EPSD	COSMIC	4.810	Loss
CAMK_CAMK2_CAMK2A_ST	Q9NQC7	CYLD	Q9UQM7	CAMK2A	S547	S552C	552	Missense	distal	5	no	6.832	6.398	EPSD	COSMIC	4.810	Down-regulation
CAMK_CAMK2_CAMK2A_ST	Q9NQC7	CYLD	Q9UQM7	CAMK2A	S560	C558Y	558	Missense	proximal	-2	no	8.079	8.735	EPSD	COSMIC	4.810	Up-regulation
CAMK_CAMK2_CAMK2A_ST	Q9NQC7	CYLD	Q9UQM7	CAMK2A	S560	S560F	560	Missense	central	0	yes	8.079	0.000	EPSD	COSMIC	4.810	Loss
CAMK_CAMK2_CAMK2A_ST	Q9NQC7	CYLD	Q9UQM7	CAMK2A	S772	I777V	777	Missense	distal	5	no	5.259	5.362	EPSD;PhosphoSitePlus	COSMIC	4.810	Up-regulation
CAMK_CAMK2_CAMK2A_ST	Q92736	RYR2	Q9UQM7	CAMK2A	S170	G172E	172	Missense	proximal	2	no	4.425	5.343	EPSD	COSMIC	4.810	Gain
CAMK_CAMK2_CAMK2A_ST	Q92736	RYR2	Q9UQM7	CAMK2A	S307	G303E	303	Missense	distal	-4	no	6.019	6.284	EPSD	COSMIC	4.810	Up-regulation
CAMK_CAMK2_CAMK2A_ST	Q92736	RYR2	Q9UQM7	CAMK2A	S307	G303R	303	Missense	distal	-4	no	6.019	6.227	EPSD	COSMIC	4.810	Up-regulation
CAMK_CAMK2_CAMK2A_ST	Q92736	RYR2	Q9UQM7	CAMK2A	S307	M309I	309	Missense	proximal	2	no	6.019	5.850	EPSD	COSMIC	4.810	Down-regulation
CAMK_CAMK2_CAMK2A_ST	Q92736	RYR2	Q9UQM7	CAMK2A	S307	D311N	311	Missense	distal	4	no	6.019	6.046	EPSD	COSMIC	4.810	Up-regulation
CAMK_CAMK2_CAMK2A_ST	Q92736	RYR2	Q9UQM7	CAMK2A	S307	L308V	308	Missense	proximal	1	no	6.019	5.862	EPSD	COSMIC	4.810	Down-regulation
CAMK_CAMK2_CAMK2A_ST	Q92736	RYR2	Q9UQM7	CAMK2A	S1049	N1046K	1046	Missense	distal	-3	no	3.637	6.203	EPSD	COSMIC	4.810	Gain
CAMK_CAMK2_CAMK2A_ST	Q92736	RYR2	Q9UQM7	CAMK2A	S2031	E2034D	2034	Missense	distal	3	no	6.199	6.077	EPSD	COSMIC	4.810	Down-regulation
CAMK_CAMK2_CAMK2A_ST	Q92736	RYR2	Q9UQM7	CAMK2A	S2031	R2026I	2026	Missense	distal	-5	no	6.199	6.069	EPSD	COSMIC	4.810	Down-regulation
CAMK_CAMK2_CAMK2A_ST	Q92736	RYR2	Q9UQM7	CAMK2A	S2031	I2025S	2025	Missense	distal	-6	no	6.199	6.224	EPSD	COSMIC	4.810	Up-regulation
CAMK_CAMK2_CAMK2A_ST	Q92736	RYR2	Q9UQM7	CAMK2A	S2031	V2036M	2036	Missense	distal	5	no	6.199	6.191	EPSD	COSMIC	4.810	Down-regulation
CAMK_CAMK2_CAMK2A_ST	Q92736	RYR2	Q9UQM7	CAMK2A	S2031	Y2038C	2038	Missense	distal	7	no	6.199	6.285	EPSD	COSMIC	4.810	Up-regulation
CAMK_CAMK2_CAMK2A_ST	Q92736	RYR2	Q9UQM7	CAMK2A	S2808	R2805H	2805	Missense	distal	-3	no	8.011	2.514	EPSD;PhosphoSitePlus	COSMIC	4.810	Loss
CAMK_CAMK2_CAMK2A_ST	Q92736	RYR2	Q9UQM7	CAMK2A	S2808	I2807V	2807	Missense	proximal	-1	no	8.011	8.016	EPSD;PhosphoSitePlus	COSMIC;CCLE	4.810	Up-regulation
CAMK_CAMK2_CAMK2A_ST	Q92736	RYR2	Q9UQM7	CAMK2A	S2808	R2803W	2803	Missense	distal	-5	no	8.011	8.159	EPSD;PhosphoSitePlus	COSMIC	4.810	Up-regulation
CAMK_CAMK2_CAMK2A_ST	Q92736	RYR2	Q9UQM7	CAMK2A	S2808	V2815L	2815	Missense	distal	7	no	8.011	8.100	EPSD;PhosphoSitePlus	COSMIC	4.810	Up-regulation
CAMK_CAMK2_CAMK2A_ST	Q92736	RYR2	Q9UQM7	CAMK2A	S2808	I2807T	2807	Missense	proximal	-1	no	8.011	8.024	EPSD;PhosphoSitePlus	COSMIC	4.810	Up-regulation
CAMK_CAMK2_CAMK2A_ST	Q92736	RYR2	Q9UQM7	CAMK2A	S2808	R2806L	2806	Missense	proximal	-2	no	8.011	7.837	EPSD;PhosphoSitePlus	COSMIC	4.810	Down-regulation
CAMK_CAMK2_CAMK2A_ST	Q92736	RYR2	Q9UQM7	CAMK2A	S2814	A2817T	2817	Missense	distal	3	no	6.412	6.177	PhosphoSitePlus;EPSD	COSMIC	4.810	Down-regulation
CAMK_CAMK2_CAMK2A_ST	Q92736	RYR2	Q9UQM7	CAMK2A	S2814	I2807V	2807	Missense	distal	-7	no	6.412	6.441	PhosphoSitePlus;EPSD	COSMIC;CCLE	4.810	Up-regulation
CAMK_CAMK2_CAMK2A_ST	Q92736	RYR2	Q9UQM7	CAMK2A	S2814	D2816G	2816	Missense	proximal	2	no	6.412	4.577	PhosphoSitePlus;EPSD	COSMIC	4.810	Loss
CAMK_CAMK2_CAMK2A_ST	Q92736	RYR2	Q9UQM7	CAMK2A	S2814	V2815L	2815	Missense	proximal	1	no	6.412	6.569	PhosphoSitePlus;EPSD	COSMIC	4.810	Up-regulation
CAMK_CAMK2_CAMK2A_ST	Q92736	RYR2	Q9UQM7	CAMK2A	S2814	I2807T	2807	Missense	distal	-7	no	6.412	6.342	PhosphoSitePlus;EPSD	COSMIC	4.810	Down-regulation
CAMK_CAMK2_CAMK2A_ST	Q92736	RYR2	Q9UQM7	CAMK2A	S2814	H2819N	2819	Missense	distal	5	no	6.412	6.327	PhosphoSitePlus;EPSD	COSMIC	4.810	Down-regulation
CAMK_CAMK2_CAMK2A_ST	Q92736	RYR2	Q9UQM7	CAMK2A	S3713	E3710K	3710	Missense	distal	-3	no	2.992	5.842	EPSD	COSMIC	4.810	Gain
CAMK_CAMK2_CAMK2A_ST	Q92736	RYR2	Q9UQM7	CAMK2A	S4260	R4257Q	4257	Missense	distal	-3	no	6.307	2.735	EPSD	COSMIC	4.810	Loss
CAMK_CAMK2_CAMK2A_ST	Q92736	RYR2	Q9UQM7	CAMK2A	S4260	K4266R	4266	Missense	distal	6	no	6.307	6.340	EPSD	COSMIC	4.810	Up-regulation
CAMK_CAMK2_CAMK2A_ST	Q92736	RYR2	Q9UQM7	CAMK2A	S4260	M4258K	4258	Missense	proximal	-2	no	6.307	6.370	EPSD	COSMIC	4.810	Up-regulation
CAMK_CAMK2_CAMK2A_ST	Q92736	RYR2	Q9UQM7	CAMK2A	S4260	M4258I	4258	Missense	proximal	-2	no	6.307	6.055	EPSD	COSMIC	4.810	Down-regulation
CAMK_CAMK2_CAMK2A_ST	Q9UQL6	HDAC5	Q9UQM7	CAMK2A	S16	L20M	20	Missense	distal	4	no	10.215	10.298	EPSD	COSMIC	4.810	Up-regulation
CAMK_CAMK2_CAMK2A_ST	Q9UQL6	HDAC5	Q9UQM7	CAMK2A	S16	R13W	13	Missense	distal	-3	no	10.215	-1.805	EPSD	COSMIC	4.810	Loss
CAMK_CAMK2_CAMK2A_ST	Q9UQL6	HDAC5	Q9UQM7	CAMK2A	S16	L17F	17	Missense	proximal	1	no	10.215	10.109	EPSD	COSMIC	4.810	Down-regulation
CAMK_CAMK2_CAMK2A_ST	Q9UQL6	HDAC5	Q9UQM7	CAMK2A	S16	E18Q	18	Missense	proximal	2	no	10.215	9.085	EPSD	COSMIC	4.810	Down-regulation
CAMK_CAMK2_CAMK2A_ST	Q9UQL6	HDAC5	Q9UQM7	CAMK2A	S16	G12R	12	Missense	distal	-4	no	10.215	10.423	EPSD	COSMIC	4.810	Up-regulation
CAMK_CAMK2_CAMK2A_ST	Q9UQL6	HDAC5	Q9UQM7	CAMK2A	S220	L221F	221	Missense	proximal	1	no	6.004	5.898	EPSD	COSMIC	4.810	Down-regulation
CAMK_CAMK2_CAMK2A_ST	Q9UQL6	HDAC5	Q9UQM7	CAMK2A	S220	S224R	224	Missense	distal	4	no	6.004	5.832	EPSD	COSMIC	4.810	Down-regulation
CAMK_CAMK2_CAMK2A_ST	Q9UQL6	HDAC5	Q9UQM7	CAMK2A	S259	R255C	255	Missense	distal	-4	no	8.004	7.369	EPSD;PhosphoSitePlus	COSMIC	4.810	Down-regulation
CAMK_CAMK2_CAMK2A_ST	Q9UQL6	HDAC5	Q9UQM7	CAMK2A	S259	R266C	266	Missense	distal	7	no	8.004	8.160	EPSD;PhosphoSitePlus	COSMIC	4.810	Up-regulation
CAMK_CAMK2_CAMK2A_ST	Q9UQL6	HDAC5	Q9UQM7	CAMK2A	S259	R266H	266	Missense	distal	7	no	8.004	7.956	EPSD;PhosphoSitePlus	COSMIC	4.810	Down-regulation
CAMK_CAMK2_CAMK2A_ST	Q9UQL6	HDAC5	Q9UQM7	CAMK2A	S279	R284C	284	Missense	distal	5	no	6.657	6.365	EPSD	COSMIC	4.810	Down-regulation
CAMK_CAMK2_CAMK2A_ST	Q9UQL6	HDAC5	Q9UQM7	CAMK2A	S279	S279N	279	Missense	central	0	yes	6.657	0.000	EPSD	COSMIC	4.810	Loss
CAMK_CAMK2_CAMK2A_ST	Q9UQL6	HDAC5	Q9UQM7	CAMK2A	S279	R284S	284	Missense	distal	5	no	6.657	6.798	EPSD	COSMIC	4.810	Up-regulation
CAMK_CAMK2_CAMK2A_ST	Q9UQL6	HDAC5	Q9UQM7	CAMK2A	S458	R455Q	455	Missense	distal	-3	no	6.903	3.332	EPSD	COSMIC	4.810	Loss
CAMK_CAMK2_CAMK2A_ST	Q9UQL6	HDAC5	Q9UQM7	CAMK2A	S458	R455W	455	Missense	distal	-3	no	6.903	-5.117	EPSD	COSMIC	4.810	Loss
CAMK_CAMK2_CAMK2A_ST	Q9UQL6	HDAC5	Q9UQM7	CAMK2A	S458	L460I	460	Missense	proximal	2	no	6.903	7.145	EPSD	COSMIC	4.810	Up-regulation
CAMK_CAMK2_CAMK2A_ST	Q9UQL6	HDAC5	Q9UQM7	CAMK2A	T479	R476H	476	Missense	distal	-3	no	5.615	0.117	EPSD	COSMIC	4.810	Loss
CAMK_CAMK2_CAMK2A_ST	Q9UQL6	HDAC5	Q9UQM7	CAMK2A	T479	T473M	473	Missense	distal	-6	no	5.615	5.463	EPSD	COSMIC	4.810	Down-regulation
CAMK_CAMK2_CAMK2A_ST	Q9UQL6	HDAC5	Q9UQM7	CAMK2A	T479	G474C	474	Missense	distal	-5	no	5.615	5.507	EPSD	COSMIC	4.810	Down-regulation
CAMK_CAMK2_CAMK2A_ST	Q9UQL6	HDAC5	Q9UQM7	CAMK2A	T479	R476C	476	Missense	distal	-3	no	5.615	0.034	EPSD	COSMIC	4.810	Loss
CAMK_CAMK2_CAMK2A_ST	Q9UQL6	HDAC5	Q9UQM7	CAMK2A	T479	T483M	483	Missense	distal	4	no	5.615	5.579	EPSD	COSMIC	4.810	Down-regulation
CAMK_CAMK2_CAMK2A_ST	Q9UQL6	HDAC5	Q9UQM7	CAMK2A	T479	A478V	478	Missense	proximal	-1	no	5.615	5.391	EPSD	COSMIC;CCLE	4.810	Down-regulation
CAMK_CAMK2_CAMK2A_ST	Q9UQL6	HDAC5	Q9UQM7	CAMK2A	T479	R482W	482	Missense	distal	3	no	5.615	5.063	EPSD	COSMIC	4.810	Down-regulation
CAMK_CAMK2_CAMK2A_ST	Q9UQL6	HDAC5	Q9UQM7	CAMK2A	S498	R491W	491	Missense	distal	-7	no	5.901	6.645	PhosphoSitePlus;EPSD	COSMIC	4.810	Up-regulation
CAMK_CAMK2_CAMK2A_ST	Q9UQL6	HDAC5	Q9UQM7	CAMK2A	S661	R658L	658	Missense	distal	-3	no	5.870	0.748	EPSD	COSMIC	4.810	Loss
CAMK_CAMK2_CAMK2A_ST	Q9UQL6	HDAC5	Q9UQM7	CAMK2A	S661	R658H	658	Missense	distal	-3	no	5.870	0.373	EPSD	COSMIC	4.810	Loss
CAMK_CAMK2_CAMK2A_ST	Q9UQL6	HDAC5	Q9UQM7	CAMK2A	S661	T659S	659	Missense	proximal	-2	no	5.870	5.913	EPSD	COSMIC	4.810	Up-regulation
CAMK_CAMK2_CAMK2A_ST	Q9UQL6	HDAC5	Q9UQM7	CAMK2A	S713	R717H	717	Missense	distal	4	no	6.895	7.006	EPSD	COSMIC	4.810	Up-regulation
CAMK_CAMK2_CAMK2A_ST	Q9UQL6	HDAC5	Q9UQM7	CAMK2A	S713	R710Q	710	Missense	distal	-3	no	6.895	3.323	EPSD	COSMIC	4.810	Loss
CAMK_CAMK2_CAMK2A_ST	Q9UQL6	HDAC5	Q9UQM7	CAMK2A	S713	Q719H	719	Missense	distal	6	no	6.895	6.863	EPSD	COSMIC	4.810	Down-regulation
CAMK_CAMK2_CAMK2A_ST	Q9UQL6	HDAC5	Q9UQM7	CAMK2A	S713	S713G	713	Missense	central	0	yes	6.895	0.000	EPSD	COSMIC	4.810	Loss
CAMK_CAMK2_CAMK2A_ST	Q9UQL6	HDAC5	Q9UQM7	CAMK2A	S1108	E1106K	1106	Missense	proximal	-2	no	9.007	9.231	EPSD	COSMIC	4.810	Up-regulation
CAMK_CAMK2_CAMK2A_ST	Q9UQL6	HDAC5	Q9UQM7	CAMK2A	S1108	A1104T	1104	Missense	distal	-4	no	9.007	8.717	EPSD	COSMIC;CCLE	4.810	Down-regulation
CAMK_CAMK2_CAMK2A_ST	P08670	VIM	Q9UQM7	CAMK2A	S7	R4K	4	Missense	distal	-3	no	6.604	4.336	EPSD	COSMIC	4.810	Loss
CAMK_CAMK2_CAMK2A_ST	P08670	VIM	Q9UQM7	CAMK2A	S26	S27R	27	Missense	proximal	1	no	9.397	9.210	EPSD	COSMIC	4.810	Down-regulation
CAMK_CAMK2_CAMK2A_ST	P08670	VIM	Q9UQM7	CAMK2A	S39	R36H	36	Missense	distal	-3	no	8.979	3.482	EPSD	COSMIC	4.810	Loss
CAMK_CAMK2_CAMK2A_ST	P08670	VIM	Q9UQM7	CAMK2A	S39	S34P	34	Missense	distal	-5	no	8.979	8.981	EPSD	COSMIC	4.810	Up-regulation
CAMK_CAMK2_CAMK2A_ST	P08670	VIM	Q9UQM7	CAMK2A	T48	S55A	55	Missense	distal	7	no	8.934	8.980	EPSD	COSMIC	4.810	Up-regulation
CAMK_CAMK2_CAMK2A_ST	P08670	VIM	Q9UQM7	CAMK2A	T48	S51N	51	Missense	distal	3	no	8.934	8.820	EPSD	COSMIC	4.810	Down-regulation
CAMK_CAMK2_CAMK2A_ST	P08670	VIM	Q9UQM7	CAMK2A	S72	R71Q	71	Missense	proximal	-1	no	7.061	7.306	EPSD	COSMIC	4.810	Up-regulation
CAMK_CAMK2_CAMK2A_ST	P08670	VIM	Q9UQM7	CAMK2A	S72	S65F	65	Missense	distal	-7	no	7.061	7.622	EPSD	COSMIC	4.810	Up-regulation
CAMK_CAMK2_CAMK2A_ST	P08670	VIM	Q9UQM7	CAMK2A	S72	V77L	77	Missense	distal	5	no	7.061	6.938	EPSD	COSMIC	4.810	Down-regulation
CAMK_CAMK2_CAMK2A_ST	P08670	VIM	Q9UQM7	CAMK2A	S72	R69C	69	Missense	distal	-3	no	7.061	1.480	EPSD	COSMIC	4.810	Loss
CAMK_CAMK2_CAMK2A_ST	P08670	VIM	Q9UQM7	CAMK2A	S83	V77L	77	Missense	distal	-6	no	6.036	6.050	PhosphoSitePlus	COSMIC	4.810	Up-regulation
CAMK_CAMK2_CAMK2A_ST	P08670	VIM	Q9UQM7	CAMK2A	S226	A232S	232	Missense	distal	6	no	7.015	6.973	EPSD	COSMIC;CCLE	4.810	Down-regulation
CAMK_CAMK2_CAMK2A_ST	P08670	VIM	Q9UQM7	CAMK2A	S226	A232V	232	Missense	distal	6	no	7.015	6.852	EPSD	COSMIC	4.810	Down-regulation
CAMK_CAMK2_CAMK2A_ST	P08670	VIM	Q9UQM7	CAMK2A	S226	E229K	229	Missense	distal	3	no	7.015	6.851	EPSD	COSMIC	4.810	Down-regulation
CAMK_CAMK2_CAMK2A_ST	P08670	VIM	Q9UQM7	CAMK2A	S316	A312T	312	Missense	distal	-4	no	5.044	4.754	EPSD	COSMIC	4.810	Loss
CAMK_CAMK2_CAMK2A_ST	P08670	VIM	Q9UQM7	CAMK2A	S316	R310H	310	Missense	distal	-6	no	5.044	4.997	EPSD	COSMIC	4.810	Down-regulation
CAMK_CAMK2_CAMK2A_ST	P08670	VIM	Q9UQM7	CAMK2A	S316	S316P	316	Missense	central	0	yes	5.044	0.000	EPSD	COSMIC;GDSC;CCLE	4.810	Loss
CAMK_CAMK2_CAMK2A_ST	P08670	VIM	Q9UQM7	CAMK2A	T449	E448K	448	Missense	proximal	-1	no	5.469	5.288	EPSD	COSMIC	4.810	Down-regulation
CAMK_CAMK2_CAMK2A_ST	P08670	VIM	Q9UQM7	CAMK2A	T449	T446R	446	Missense	distal	-3	no	5.469	10.526	EPSD	COSMIC	4.810	Up-regulation
CAMK_CAMK2_CAMK2A_ST	P08670	VIM	Q9UQM7	CAMK2A	T449	Q453E	453	Missense	distal	4	no	5.469	5.601	EPSD	COSMIC;GDSC;CCLE	4.810	Up-regulation
CAMK_CAMK2_CAMK2A_ST	P08670	VIM	Q9UQM7	CAMK2A	T449	I455V	455	Missense	distal	6	no	5.469	5.438	EPSD	COSMIC	4.810	Down-regulation
CAMK_CAMK2_CAMK2A_ST	P08670	VIM	Q9UQM7	CAMK2A	T449	V447A	447	Missense	proximal	-2	no	5.469	5.887	EPSD	COSMIC	4.810	Up-regulation
CAMK_CAMK2_CAMK2A_ST	O14713	ITGB1BP1	Q9UQM7	CAMK2A	S10	Q15K	15	Missense	distal	5	no	5.399	5.509	EPSD	COSMIC	4.810	Up-regulation
CAMK_CAMK2_CAMK2A_ST	O14713	ITGB1BP1	Q9UQM7	CAMK2A	S10	G5D	5	Missense	distal	-5	no	5.399	5.415	EPSD	COSMIC	4.810	Up-regulation
CAMK_CAMK2_CAMK2A_ST	O14713	ITGB1BP1	Q9UQM7	CAMK2A	S10	S14P	14	Missense	distal	4	no	5.399	5.226	EPSD	COSMIC	4.810	Down-regulation
CAMK_CAMK2_CAMK2A_ST	O14713	ITGB1BP1	Q9UQM7	CAMK2A	S11	Q15K	15	Missense	distal	4	no	8.579	8.535	EPSD	COSMIC	4.810	Down-regulation
CAMK_CAMK2_CAMK2A_ST	O14713	ITGB1BP1	Q9UQM7	CAMK2A	S11	G5D	5	Missense	distal	-6	no	8.579	8.566	EPSD	COSMIC	4.810	Down-regulation
CAMK_CAMK2_CAMK2A_ST	O14713	ITGB1BP1	Q9UQM7	CAMK2A	S11	S14P	14	Missense	distal	3	no	8.579	8.308	EPSD	COSMIC	4.810	Down-regulation
CAMK_CAMK2_CAMK2A_ST	O14713	ITGB1BP1	Q9UQM7	CAMK2A	S16	Q15K	15	Missense	proximal	-1	no	6.890	6.796	EPSD	COSMIC	4.810	Down-regulation
CAMK_CAMK2_CAMK2A_ST	O14713	ITGB1BP1	Q9UQM7	CAMK2A	S16	S14P	14	Missense	proximal	-2	no	6.890	6.897	EPSD	COSMIC	4.810	Up-regulation
CAMK_CAMK2_CAMK2A_ST	O14713	ITGB1BP1	Q9UQM7	CAMK2A	S17	Q15K	15	Missense	proximal	-2	no	7.238	7.197	EPSD	COSMIC	4.810	Down-regulation
CAMK_CAMK2_CAMK2A_ST	O14713	ITGB1BP1	Q9UQM7	CAMK2A	S17	S14P	14	Missense	distal	-3	no	7.238	6.781	EPSD	COSMIC	4.810	Down-regulation
CAMK_CAMK2_CAMK2A_ST	O14713	ITGB1BP1	Q9UQM7	CAMK2A	T38	R35Q	35	Missense	distal	-3	no	7.523	3.952	PhosphoSitePlus	COSMIC	4.810	Loss
CAMK_CAMK2_CAMK2A_ST	O14713	ITGB1BP1	Q9UQM7	CAMK2A	S41	S46F	46	Missense	distal	5	no	5.153	4.892	EPSD	COSMIC	4.810	Down-regulation
CAMK_CAMK2_CAMK2A_ST	O14713	ITGB1BP1	Q9UQM7	CAMK2A	S41	R35Q	35	Missense	distal	-6	no	5.153	5.156	EPSD	COSMIC	4.810	Up-regulation
CAMK_CAMK2_CAMK2A_ST	P31645	SLC6A4	Q9UQM7	CAMK2A	S13	L12Q	12	Missense	proximal	-1	no	5.858	6.225	PhosphoSitePlus	COSMIC	4.810	Up-regulation
CAMK_CAMK2_CAMK2A_ST	P31645	SLC6A4	Q9UQM7	CAMK2A	S13	C15S	15	Missense	proximal	2	no	5.858	5.880	PhosphoSitePlus	COSMIC	4.810	Up-regulation
CAMK_CAMK2_CAMK2A_ST	P31645	SLC6A4	Q9UQM7	CAMK2A	S40	Y47C	47	Missense	distal	7	no	6.166	6.252	EPSD	COSMIC	4.810	Up-regulation
CAMK_CAMK2_CAMK2A_ST	P21333	FLNA	Q9UQM7	CAMK2A	T23	A16D	16	Missense	distal	-7	no	4.402	4.851	EPSD	COSMIC	4.810	Gain
CAMK_CAMK2_CAMK2A_ST	P21333	FLNA	Q9UQM7	CAMK2A	S189	G195S	195	Missense	distal	6	no	5.741	5.801	EPSD	COSMIC	4.810	Up-regulation
CAMK_CAMK2_CAMK2A_ST	P21333	FLNA	Q9UQM7	CAMK2A	S189	R196W	196	Missense	distal	7	no	5.741	6.057	EPSD	COSMIC	4.810	Up-regulation
CAMK_CAMK2_CAMK2A_ST	P21333	FLNA	Q9UQM7	CAMK2A	S343	D337N	337	Missense	distal	-6	no	5.546	5.568	EPSD	COSMIC	4.810	Up-regulation
CAMK_CAMK2_CAMK2A_ST	P21333	FLNA	Q9UQM7	CAMK2A	S343	N339H	339	Missense	distal	-4	no	5.546	5.516	EPSD	COSMIC	4.810	Down-regulation
CAMK_CAMK2_CAMK2A_ST	P21333	FLNA	Q9UQM7	CAMK2A	S343	V350L	350	Missense	distal	7	no	5.546	5.634	EPSD	COSMIC	4.810	Up-regulation
CAMK_CAMK2_CAMK2A_ST	P21333	FLNA	Q9UQM7	CAMK2A	S377	V372L	372	Missense	distal	-5	no	4.795	4.819	EPSD	COSMIC	4.810	Gain
CAMK_CAMK2_CAMK2A_ST	P21333	FLNA	Q9UQM7	CAMK2A	S512	G509S	509	Missense	distal	-3	no	4.723	4.860	EPSD	COSMIC	4.810	Gain
CAMK_CAMK2_CAMK2A_ST	P21333	FLNA	Q9UQM7	CAMK2A	S869	A872T	872	Missense	distal	3	no	5.871	5.635	EPSD	COSMIC;GDSC	4.810	Down-regulation
CAMK_CAMK2_CAMK2A_ST	P21333	FLNA	Q9UQM7	CAMK2A	S869	A872S	872	Missense	distal	3	no	5.871	5.830	EPSD	COSMIC	4.810	Down-regulation
CAMK_CAMK2_CAMK2A_ST	P21333	FLNA	Q9UQM7	CAMK2A	S962	S959R	959	Missense	distal	-3	no	2.682	7.142	EPSD	COSMIC	4.810	Gain
CAMK_CAMK2_CAMK2A_ST	P21333	FLNA	Q9UQM7	CAMK2A	S968	K975N	975	Missense	distal	7	no	6.182	6.162	EPSD	COSMIC;GDSC;CCLE	4.810	Down-regulation
CAMK_CAMK2_CAMK2A_ST	P21333	FLNA	Q9UQM7	CAMK2A	S1330	Y1324C	1324	Missense	distal	-6	no	5.797	5.916	EPSD	COSMIC	4.810	Up-regulation
CAMK_CAMK2_CAMK2A_ST	P21333	FLNA	Q9UQM7	CAMK2A	S1330	S1330F	1330	Missense	central	0	yes	5.797	0.000	EPSD	COSMIC	4.810	Loss
CAMK_CAMK2_CAMK2A_ST	P21333	FLNA	Q9UQM7	CAMK2A	S1409	V1412F	1412	Missense	distal	3	no	6.215	5.859	EPSD	COSMIC	4.810	Down-regulation
CAMK_CAMK2_CAMK2A_ST	P21333	FLNA	Q9UQM7	CAMK2A	S1409	V1412A	1412	Missense	distal	3	no	6.215	6.277	EPSD	COSMIC	4.810	Up-regulation
CAMK_CAMK2_CAMK2A_ST	P21333	FLNA	Q9UQM7	CAMK2A	S1409	I1415M	1415	Missense	distal	6	no	6.215	6.268	EPSD	COSMIC	4.810	Up-regulation
CAMK_CAMK2_CAMK2A_ST	P21333	FLNA	Q9UQM7	CAMK2A	S1423	Y1417F	1417	Missense	distal	-6	no	5.362	5.447	EPSD	COSMIC	4.810	Up-regulation
CAMK_CAMK2_CAMK2A_ST	P21333	FLNA	Q9UQM7	CAMK2A	S1812	G1806V	1806	Missense	distal	-6	no	6.255	6.203	EPSD	COSMIC	4.810	Down-regulation
CAMK_CAMK2_CAMK2A_ST	P21333	FLNA	Q9UQM7	CAMK2A	S1812	T1805I	1805	Missense	distal	-7	no	6.255	6.326	EPSD	COSMIC	4.810	Up-regulation
CAMK_CAMK2_CAMK2A_ST	P21333	FLNA	Q9UQM7	CAMK2A	S2152	R2149Q	2149	Missense	distal	-3	no	5.835	2.264	EPSD	COSMIC	4.810	Loss
CAMK_CAMK2_CAMK2A_ST	P21333	FLNA	Q9UQM7	CAMK2A	S2152	P2151S	2151	Missense	proximal	-1	no	5.835	6.021	EPSD	COSMIC	4.810	Up-regulation
CAMK_CAMK2_CAMK2A_ST	P21333	FLNA	Q9UQM7	CAMK2A	S2152	V2156I	2156	Missense	distal	4	no	5.835	5.679	EPSD	COSMIC	4.810	Down-regulation
CAMK_CAMK2_CAMK2A_ST	P21333	FLNA	Q9UQM7	CAMK2A	S2152	R2149W	2149	Missense	distal	-3	no	5.835	-6.185	EPSD	COSMIC	4.810	Loss
CAMK_CAMK2_CAMK2A_ST	P21333	FLNA	Q9UQM7	CAMK2A	S2152	V2153A	2153	Missense	proximal	1	no	5.835	5.484	EPSD	COSMIC	4.810	Down-regulation
CAMK_CAMK2_CAMK2A_ST	P21333	FLNA	Q9UQM7	CAMK2A	S2180	G2183A	2183	Missense	distal	3	no	5.438	5.629	EPSD	COSMIC	4.810	Up-regulation
CAMK_CAMK2_CAMK2A_ST	P21333	FLNA	Q9UQM7	CAMK2A	S2180	S2182L	2182	Missense	proximal	2	no	5.438	5.125	EPSD	COSMIC	4.810	Down-regulation
CAMK_CAMK2_CAMK2A_ST	P21333	FLNA	Q9UQM7	CAMK2A	S2180	K2184R	2184	Missense	distal	4	no	5.438	5.313	EPSD	COSMIC	4.810	Down-regulation
CAMK_CAMK2_CAMK2A_ST	P21333	FLNA	Q9UQM7	CAMK2A	S2284	E2282D	2282	Missense	proximal	-2	no	6.163	5.857	EPSD	COSMIC	4.810	Down-regulation
CAMK_CAMK2_CAMK2A_ST	P21333	FLNA	Q9UQM7	CAMK2A	S2284	R2288S	2288	Missense	distal	4	no	6.163	6.334	EPSD	COSMIC	4.810	Up-regulation
CAMK_CAMK2_CAMK2A_ST	P21333	FLNA	Q9UQM7	CAMK2A	S2284	R2288C	2288	Missense	distal	4	no	6.163	5.970	EPSD	COSMIC	4.810	Down-regulation
CAMK_CAMK2_CAMK2A_ST	P21333	FLNA	Q9UQM7	CAMK2A	S2292	R2288S	2288	Missense	distal	-4	no	5.353	5.421	EPSD	COSMIC	4.810	Up-regulation
CAMK_CAMK2_CAMK2A_ST	P21333	FLNA	Q9UQM7	CAMK2A	S2292	R2288C	2288	Missense	distal	-4	no	5.353	4.718	EPSD	COSMIC	4.810	Loss
CAMK_CAMK2_CAMK2A_ST	P21333	FLNA	Q9UQM7	CAMK2A	S2292	V2298D	2298	Missense	distal	6	no	5.353	5.504	EPSD	COSMIC	4.810	Up-regulation
CAMK_CAMK2_CAMK2A_ST	P21333	FLNA	Q9UQM7	CAMK2A	S2292	V2295M	2295	Missense	distal	3	no	5.353	5.193	EPSD	COSMIC	4.810	Down-regulation
CAMK_CAMK2_CAMK2A_ST	P21333	FLNA	Q9UQM7	CAMK2A	T2336	V2337F	2337	Missense	proximal	1	no	5.750	5.801	EPSD	COSMIC	4.810	Up-regulation
CAMK_CAMK2_CAMK2A_ST	P21333	FLNA	Q9UQM7	CAMK2A	T2336	V2337I	2337	Missense	proximal	1	no	5.750	5.958	EPSD	COSMIC	4.810	Up-regulation
CAMK_CAMK2_CAMK2A_ST	P21333	FLNA	Q9UQM7	CAMK2A	T2336	S2343N	2343	Missense	distal	7	no	5.750	5.797	EPSD	COSMIC	4.810	Up-regulation
CAMK_CAMK2_CAMK2A_ST	P21333	FLNA	Q9UQM7	CAMK2A	S2352	F2353C	2353	Missense	proximal	1	no	5.610	5.207	EPSD	COSMIC	4.810	Down-regulation
CAMK_CAMK2_CAMK2A_ST	P21333	FLNA	Q9UQM7	CAMK2A	S2370	D2365N	2365	Missense	distal	-5	no	5.270	5.282	EPSD	COSMIC	4.810	Up-regulation
CAMK_CAMK2_CAMK2A_ST	P21333	FLNA	Q9UQM7	CAMK2A	S2370	S2370N	2370	Missense	central	0	yes	5.270	0.000	EPSD	COSMIC	4.810	Loss
CAMK_CAMK2_CAMK2A_ST	P21333	FLNA	Q9UQM7	CAMK2A	S2523	V2522I	2522	Missense	proximal	-1	no	9.339	9.334	PhosphoSitePlus	COSMIC	4.810	Down-regulation
CAMK_CAMK2_CAMK2A_ST	P21333	FLNA	Q9UQM7	CAMK2A	S2523	H2528Q	2528	Missense	distal	5	no	9.339	9.224	PhosphoSitePlus	COSMIC	4.810	Down-regulation
CAMK_CAMK2_CAMK2A_ST	P21333	FLNA	Q9UQM7	CAMK2A	S2523	H2525P	2525	Missense	proximal	2	no	9.339	9.505	PhosphoSitePlus	COSMIC	4.810	Up-regulation
CAMK_CAMK2_CAMK2A_ST	P21333	FLNA	Q9UQM7	CAMK2A	T2579	D2581H	2581	Missense	proximal	2	no	5.085	2.601	EPSD	COSMIC;GDSC	4.810	Loss
CAMK_CAMK2_CAMK2A_ST	P21333	FLNA	Q9UQM7	CAMK2A	T2579	V2572I	2572	Missense	distal	-7	no	5.085	5.057	EPSD	COSMIC;GDSC;CCLE	4.810	Down-regulation
CAMK_CAMK2_CAMK2A_ST	P21333	FLNA	Q9UQM7	CAMK2A	S2615	Y2618C	2618	Missense	distal	3	no	6.393	6.375	EPSD	COSMIC	4.810	Down-regulation
CAMK_CAMK2_CAMK2A_ST	Q96A00	PPP1R14A	Q9UQM7	CAMK2A	S16	A20T	20	Missense	distal	4	no	6.911	6.873	EPSD	COSMIC	4.810	Down-regulation
CAMK_CAMK2_CAMK2A_ST	Q96A00	PPP1R14A	Q9UQM7	CAMK2A	S16	P23A	23	Missense	distal	7	no	6.911	6.859	EPSD	COSMIC	4.810	Down-regulation
CAMK_CAMK2_CAMK2A_ST	Q96A00	PPP1R14A	Q9UQM7	CAMK2A	S18	A20T	20	Missense	proximal	2	no	5.168	4.502	EPSD	COSMIC	4.810	Loss
CAMK_CAMK2_CAMK2A_ST	Q96A00	PPP1R14A	Q9UQM7	CAMK2A	S18	P23A	23	Missense	distal	5	no	5.168	5.449	EPSD	COSMIC	4.810	Up-regulation
CAMK_CAMK2_CAMK2A_ST	Q96A00	PPP1R14A	Q9UQM7	CAMK2A	S128	P122L	122	Missense	distal	-6	no	9.054	9.059	EPSD	COSMIC	4.810	Up-regulation
CAMK_CAMK2_CAMK2A_ST	Q96A00	PPP1R14A	Q9UQM7	CAMK2A	S130	S136N	136	Missense	distal	6	no	5.910	5.909	PhosphoSitePlus	COSMIC	4.810	Down-regulation
CAMK_CAMK2_CAMK2A_ST	O43526	KCNQ2	Q9UQM7	CAMK2A	T368	S374L	374	Missense	distal	6	no	5.128	5.013	EPSD	COSMIC	4.810	Down-regulation
CAMK_CAMK2_CAMK2A_ST	O43526	KCNQ2	Q9UQM7	CAMK2A	S445	L439M	439	Missense	distal	-6	no	7.611	7.475	EPSD	COSMIC	4.810	Down-regulation
CAMK_CAMK2_CAMK2A_ST	O43526	KCNQ2	Q9UQM7	CAMK2A	S445	V450A	450	Missense	distal	5	no	7.611	7.829	EPSD	COSMIC	4.810	Up-regulation
CAMK_CAMK2_CAMK2A_ST	O43526	KCNQ2	Q9UQM7	CAMK2A	S445	A452V	452	Missense	distal	7	no	7.611	7.640	EPSD	COSMIC	4.810	Up-regulation
CAMK_CAMK2_CAMK2A_ST	O43526	KCNQ2	Q9UQM7	CAMK2A	S445	S445Y	445	Missense	central	0	yes	7.611	0.000	EPSD	COSMIC	4.810	Loss
CAMK_CAMK2_CAMK2A_ST	O43526	KCNQ2	Q9UQM7	CAMK2A	S445	S446I	446	Missense	proximal	1	no	7.611	7.953	EPSD	COSMIC	4.810	Up-regulation
CAMK_CAMK2_CAMK2A_ST	O43526	KCNQ2	Q9UQM7	CAMK2A	S468	P467Q	467	Missense	proximal	-1	no	9.877	10.219	EPSD	COSMIC	4.810	Up-regulation
CAMK_CAMK2_CAMK2A_ST	O43526	KCNQ2	Q9UQM7	CAMK2A	S468	R465H	465	Missense	distal	-3	no	9.877	4.380	EPSD	COSMIC	4.810	Loss
CAMK_CAMK2_CAMK2A_ST	O43526	KCNQ2	Q9UQM7	CAMK2A	S468	S472C	472	Missense	distal	4	no	9.877	9.513	EPSD	COSMIC	4.810	Down-regulation
CAMK_CAMK2_CAMK2A_ST	O43526	KCNQ2	Q9UQM7	CAMK2A	S468	A469T	469	Missense	proximal	1	no	9.877	9.976	EPSD	COSMIC	4.810	Up-regulation
CAMK_CAMK2_CAMK2A_ST	O43526	KCNQ2	Q9UQM7	CAMK2A	S503	F496L	496	Missense	distal	-7	no	4.957	4.490	EPSD	COSMIC	4.810	Loss
CAMK_CAMK2_CAMK2A_ST	O43526	KCNQ2	Q9UQM7	CAMK2A	S503	E509Q	509	Missense	distal	6	no	4.957	4.945	EPSD	COSMIC	4.810	Down-regulation
CAMK_CAMK2_CAMK2A_ST	O43526	KCNQ2	Q9UQM7	CAMK2A	S503	K499N	499	Missense	distal	-4	no	4.957	4.854	EPSD	COSMIC	4.810	Down-regulation
CAMK_CAMK2_CAMK2A_ST	O43526	KCNQ2	Q9UQM7	CAMK2A	S507	E509Q	509	Missense	proximal	2	no	10.358	9.228	EPSD	COSMIC	4.810	Down-regulation
CAMK_CAMK2_CAMK2A_ST	O43526	KCNQ2	Q9UQM7	CAMK2A	S507	P513S	513	Missense	distal	6	no	10.358	10.441	EPSD	COSMIC	4.810	Up-regulation
CAMK_CAMK2_CAMK2A_ST	O43526	KCNQ2	Q9UQM7	CAMK2A	S507	S511G	511	Missense	distal	4	no	10.358	10.261	EPSD	COSMIC	4.810	Down-regulation
CAMK_CAMK2_CAMK2A_ST	O43526	KCNQ2	Q9UQM7	CAMK2A	S810	S808P	808	Missense	proximal	-2	no	5.214	5.221	EPSD	COSMIC	4.810	Up-regulation
CAMK_CAMK2_CAMK2A_ST	O43526	KCNQ2	Q9UQM7	CAMK2A	S810	L814I	814	Missense	distal	4	no	5.214	5.160	EPSD	COSMIC	4.810	Down-regulation
CAMK_CAMK2_CAMK2A_ST	O43526	KCNQ2	Q9UQM7	CAMK2A	S810	S808L	808	Missense	proximal	-2	no	5.214	5.111	EPSD	COSMIC	4.810	Down-regulation
CAMK_CAMK2_CAMK2A_ST	O43526	KCNQ2	Q9UQM7	CAMK2A	S810	G804S	804	Missense	distal	-6	no	5.214	5.121	EPSD	COSMIC	4.810	Down-regulation
CAMK_CAMK2_CAMK2A_ST	O43526	KCNQ2	Q9UQM7	CAMK2A	S810	L817I	817	Missense	distal	7	no	5.214	5.241	EPSD	COSMIC	4.810	Up-regulation
CAMK_CAMK2_CAMK2A_ST	O43526	KCNQ2	Q9UQM7	CAMK2A	S810	S803R	803	Missense	distal	-7	no	5.214	5.182	EPSD	COSMIC;CCLE	4.810	Down-regulation
CAMK_CAMK2_CAMK2A_ST	O43526	KCNQ2	Q9UQM7	CAMK2A	T857	G850R	850	Missense	distal	-7	no	7.599	7.267	EPSD	COSMIC	4.810	Down-regulation
CAMK_CAMK2_CAMK2A_ST	O43526	KCNQ2	Q9UQM7	CAMK2A	T857	R854H	854	Missense	distal	-3	no	7.599	2.101	EPSD	COSMIC	4.810	Loss
CAMK_CAMK2_CAMK2A_ST	O43526	KCNQ2	Q9UQM7	CAMK2A	T857	G858S	858	Missense	proximal	1	no	7.599	8.097	EPSD	COSMIC	4.810	Up-regulation
CAMK_CAMK2_CAMK2A_ST	O43526	KCNQ2	Q9UQM7	CAMK2A	T857	P853L	853	Missense	distal	-4	no	7.599	7.679	EPSD	COSMIC	4.810	Up-regulation
CAMK_CAMK2_CAMK2A_ST	O43526	KCNQ2	Q9UQM7	CAMK2A	T857	R854C	854	Missense	distal	-3	no	7.599	2.018	EPSD	COSMIC	4.810	Loss
CAMK_CAMK2_CAMK2A_ST	O43526	KCNQ2	Q9UQM7	CAMK2A	T857	G860S	860	Missense	distal	3	no	7.599	7.749	EPSD	COSMIC	4.810	Up-regulation
CAMK_CAMK2_CAMK2A_ST	Q06210	GFPT1	Q9UQM7	CAMK2A	T98	A97G	97	Missense	proximal	-1	no	6.186	5.985	EPSD	COSMIC	4.810	Down-regulation
CAMK_CAMK2_CAMK2A_ST	Q06210	GFPT1	Q9UQM7	CAMK2A	T98	P102R	102	Missense	distal	4	no	6.186	6.187	EPSD	COSMIC	4.810	Up-regulation
CAMK_CAMK2_CAMK2A_ST	Q06210	GFPT1	Q9UQM7	CAMK2A	S205	R203Q	203	Missense	proximal	-2	no	6.530	6.747	EPSD	COSMIC	4.810	Up-regulation
CAMK_CAMK2_CAMK2A_ST	Q06210	GFPT1	Q9UQM7	CAMK2A	S242	S235R	235	Missense	distal	-7	no	6.855	6.822	EPSD	COSMIC	4.810	Down-regulation
CAMK_CAMK2_CAMK2A_ST	Q06210	GFPT1	Q9UQM7	CAMK2A	S253	C254R	254	Missense	proximal	1	no	6.269	6.299	EPSD	COSMIC	4.810	Up-regulation
CAMK_CAMK2_CAMK2A_ST	Q06210	GFPT1	Q9UQM7	CAMK2A	S253	R258L	258	Missense	distal	5	no	6.269	6.121	EPSD	COSMIC	4.810	Down-regulation
CAMK_CAMK2_CAMK2A_ST	Q06210	GFPT1	Q9UQM7	CAMK2A	S257	C254R	254	Missense	distal	-3	no	2.056	7.637	EPSD	COSMIC	4.810	Gain
CAMK_CAMK2_CAMK2A_ST	Q06210	GFPT1	Q9UQM7	CAMK2A	S261	P267L	267	Missense	distal	6	no	7.159	7.127	PhosphoSitePlus	COSMIC	4.810	Down-regulation
CAMK_CAMK2_CAMK2A_ST	Q06210	GFPT1	Q9UQM7	CAMK2A	S261	C254R	254	Missense	distal	-7	no	7.159	6.490	PhosphoSitePlus	COSMIC	4.810	Down-regulation
CAMK_CAMK2_CAMK2A_ST	Q06210	GFPT1	Q9UQM7	CAMK2A	S261	R258L	258	Missense	distal	-3	no	7.159	2.036	PhosphoSitePlus	COSMIC	4.810	Loss
CAMK_CAMK2_CAMK2A_ST	P35222	CTNNB1	Q9UQM7	CAMK2A	S23	W25R	25	Missense	proximal	2	no	3.783	5.379	EPSD	COSMIC	4.810	Gain
CAMK_CAMK2_CAMK2A_ST	P35222	CTNNB1	Q9UQM7	CAMK2A	S29	H24Y	24	Missense	distal	-5	no	4.682	4.816	EPSD	COSMIC	4.810	Gain
CAMK_CAMK2_CAMK2A_ST	P35222	CTNNB1	Q9UQM7	CAMK2A	S29	W25R	25	Missense	distal	-4	no	4.682	5.373	EPSD	COSMIC	4.810	Gain
CAMK_CAMK2_CAMK2A_ST	P35222	CTNNB1	Q9UQM7	CAMK2A	S29	W25L	25	Missense	distal	-4	no	4.682	5.144	EPSD	COSMIC	4.810	Gain
CAMK_CAMK2_CAMK2A_ST	P35222	CTNNB1	Q9UQM7	CAMK2A	S29	G34A	34	Missense	distal	5	no	4.682	4.917	EPSD	COSMIC	4.810	Gain
CAMK_CAMK2_CAMK2A_ST	P35222	CTNNB1	Q9UQM7	CAMK2A	S29	L31M	31	Missense	proximal	2	no	4.682	5.094	EPSD	COSMIC	4.810	Gain
CAMK_CAMK2_CAMK2A_ST	P35222	CTNNB1	Q9UQM7	CAMK2A	S29	Q26R	26	Missense	distal	-3	no	4.682	8.254	EPSD	COSMIC;GDSC;CCLE	4.810	Gain
CAMK_CAMK2_CAMK2A_ST	P35222	CTNNB1	Q9UQM7	CAMK2A	S37	P44S	44	Missense	distal	7	no	4.979	4.880	EPSD	COSMIC	4.810	Down-regulation
CAMK_CAMK2_CAMK2A_ST	P35222	CTNNB1	Q9UQM7	CAMK2A	S37	A43V	43	Missense	distal	6	no	4.979	4.815	EPSD	COSMIC	4.810	Down-regulation
CAMK_CAMK2_CAMK2A_ST	P35222	CTNNB1	Q9UQM7	CAMK2A	S37	A39G	39	Missense	proximal	2	no	4.979	4.945	EPSD	COSMIC	4.810	Down-regulation
CAMK_CAMK2_CAMK2A_ST	P35222	CTNNB1	Q9UQM7	CAMK2A	S37	G38A	38	Missense	proximal	1	no	4.979	5.260	EPSD	COSMIC	4.810	Up-regulation
CAMK_CAMK2_CAMK2A_ST	P35222	CTNNB1	Q9UQM7	CAMK2A	S37	T40I	40	Missense	distal	3	no	4.979	4.929	EPSD	COSMIC	4.810	Down-regulation
CAMK_CAMK2_CAMK2A_ST	P35222	CTNNB1	Q9UQM7	CAMK2A	S37	P44A	44	Missense	distal	7	no	4.979	4.926	EPSD	COSMIC	4.810	Down-regulation
CAMK_CAMK2_CAMK2A_ST	P35222	CTNNB1	Q9UQM7	CAMK2A	S37	I35T	35	Missense	proximal	-2	no	4.979	5.003	EPSD	COSMIC	4.810	Up-regulation
CAMK_CAMK2_CAMK2A_ST	P35222	CTNNB1	Q9UQM7	CAMK2A	S37	T41P	41	Missense	distal	4	no	4.979	4.898	EPSD	COSMIC	4.810	Down-regulation
CAMK_CAMK2_CAMK2A_ST	P35222	CTNNB1	Q9UQM7	CAMK2A	S37	T42R	42	Missense	distal	5	no	4.979	4.999	EPSD	COSMIC	4.810	Up-regulation
CAMK_CAMK2_CAMK2A_ST	P35222	CTNNB1	Q9UQM7	CAMK2A	S37	D32E	32	Missense	distal	-5	no	4.979	4.815	EPSD	COSMIC	4.810	Down-regulation
CAMK_CAMK2_CAMK2A_ST	P35222	CTNNB1	Q9UQM7	CAMK2A	S37	H36R	36	Missense	proximal	-1	no	4.979	4.833	EPSD	COSMIC	4.810	Down-regulation
CAMK_CAMK2_CAMK2A_ST	P35222	CTNNB1	Q9UQM7	CAMK2A	S37	T40A	40	Missense	distal	3	no	4.979	5.214	EPSD	COSMIC	4.810	Up-regulation
CAMK_CAMK2_CAMK2A_ST	P35222	CTNNB1	Q9UQM7	CAMK2A	S37	A43T	43	Missense	distal	6	no	4.979	4.889	EPSD	COSMIC	4.810	Down-regulation
CAMK_CAMK2_CAMK2A_ST	P35222	CTNNB1	Q9UQM7	CAMK2A	S37	P44L	44	Missense	distal	7	no	4.979	5.044	EPSD	COSMIC	4.810	Up-regulation
CAMK_CAMK2_CAMK2A_ST	P35222	CTNNB1	Q9UQM7	CAMK2A	S37	G34L	34	Missense	distal	-3	no	4.979	4.454	EPSD	COSMIC	4.810	Loss
CAMK_CAMK2_CAMK2A_ST	P35222	CTNNB1	Q9UQM7	CAMK2A	S37	T42I	42	Missense	distal	5	no	4.979	4.871	EPSD	COSMIC	4.810	Down-regulation
CAMK_CAMK2_CAMK2A_ST	P35222	CTNNB1	Q9UQM7	CAMK2A	S37	S33L	33	Missense	distal	-4	no	4.979	4.681	EPSD	COSMIC;CCLE	4.810	Loss
CAMK_CAMK2_CAMK2A_ST	P35222	CTNNB1	Q9UQM7	CAMK2A	S37	T42S	42	Missense	distal	5	no	4.979	5.140	EPSD	COSMIC	4.810	Up-regulation
CAMK_CAMK2_CAMK2A_ST	P35222	CTNNB1	Q9UQM7	CAMK2A	S37	T42K	42	Missense	distal	5	no	4.979	5.107	EPSD	COSMIC	4.810	Up-regulation
CAMK_CAMK2_CAMK2A_ST	P35222	CTNNB1	Q9UQM7	CAMK2A	S37	L31P	31	Missense	distal	-6	no	4.979	4.973	EPSD	COSMIC	4.810	Down-regulation
CAMK_CAMK2_CAMK2A_ST	P35222	CTNNB1	Q9UQM7	CAMK2A	S37	S37L	37	Missense	central	0	yes	4.979	0.000	EPSD	COSMIC	4.810	Loss
CAMK_CAMK2_CAMK2A_ST	P35222	CTNNB1	Q9UQM7	CAMK2A	S37	A39T	39	Missense	proximal	2	no	4.979	4.313	EPSD	COSMIC	4.810	Loss
CAMK_CAMK2_CAMK2A_ST	P35222	CTNNB1	Q9UQM7	CAMK2A	S37	S33N	33	Missense	distal	-4	no	4.979	4.816	EPSD	COSMIC	4.810	Down-regulation
CAMK_CAMK2_CAMK2A_ST	P35222	CTNNB1	Q9UQM7	CAMK2A	S37	H36Y	36	Missense	proximal	-1	no	4.979	4.784	EPSD	COSMIC	4.810	Loss
CAMK_CAMK2_CAMK2A_ST	P35222	CTNNB1	Q9UQM7	CAMK2A	S37	A43P	43	Missense	distal	6	no	4.979	4.853	EPSD	COSMIC	4.810	Down-regulation
CAMK_CAMK2_CAMK2A_ST	P35222	CTNNB1	Q9UQM7	CAMK2A	S37	Y30C	30	Missense	distal	-7	no	4.979	5.449	EPSD	COSMIC	4.810	Up-regulation
CAMK_CAMK2_CAMK2A_ST	P35222	CTNNB1	Q9UQM7	CAMK2A	S37	G38P	38	Missense	proximal	1	no	4.979	5.110	EPSD	COSMIC	4.810	Up-regulation
CAMK_CAMK2_CAMK2A_ST	P35222	CTNNB1	Q9UQM7	CAMK2A	S37	G38D	38	Missense	proximal	1	no	4.979	5.047	EPSD	COSMIC	4.810	Up-regulation
CAMK_CAMK2_CAMK2A_ST	P35222	CTNNB1	Q9UQM7	CAMK2A	S37	T42A	42	Missense	distal	5	no	4.979	5.191	EPSD	COSMIC	4.810	Up-regulation
CAMK_CAMK2_CAMK2A_ST	P35222	CTNNB1	Q9UQM7	CAMK2A	S37	I35M	35	Missense	proximal	-2	no	4.979	5.230	EPSD	COSMIC	4.810	Up-regulation
CAMK_CAMK2_CAMK2A_ST	P35222	CTNNB1	Q9UQM7	CAMK2A	S37	T40S	40	Missense	distal	3	no	4.979	5.174	EPSD	COSMIC	4.810	Up-regulation
CAMK_CAMK2_CAMK2A_ST	P35222	CTNNB1	Q9UQM7	CAMK2A	S37	G34A	34	Missense	distal	-3	no	4.979	5.157	EPSD	COSMIC	4.810	Up-regulation
CAMK_CAMK2_CAMK2A_ST	P35222	CTNNB1	Q9UQM7	CAMK2A	S37	L31W	31	Missense	distal	-6	no	4.979	5.157	EPSD	COSMIC	4.810	Up-regulation
CAMK_CAMK2_CAMK2A_ST	P35222	CTNNB1	Q9UQM7	CAMK2A	S37	T41S	41	Missense	distal	4	no	4.979	5.071	EPSD	COSMIC	4.810	Up-regulation
CAMK_CAMK2_CAMK2A_ST	P35222	CTNNB1	Q9UQM7	CAMK2A	S37	G34I	34	Missense	distal	-3	no	4.979	5.305	EPSD	COSMIC	4.810	Up-regulation
CAMK_CAMK2_CAMK2A_ST	P35222	CTNNB1	Q9UQM7	CAMK2A	S37	I35N	35	Missense	proximal	-2	no	4.979	5.196	EPSD	COSMIC	4.810	Up-regulation
CAMK_CAMK2_CAMK2A_ST	P35222	CTNNB1	Q9UQM7	CAMK2A	S37	T42Q	42	Missense	distal	5	no	4.979	4.998	EPSD	COSMIC	4.810	Up-regulation
CAMK_CAMK2_CAMK2A_ST	P35222	CTNNB1	Q9UQM7	CAMK2A	S37	D32C	32	Missense	distal	-5	no	4.979	4.855	EPSD	COSMIC	4.810	Down-regulation
CAMK_CAMK2_CAMK2A_ST	P35222	CTNNB1	Q9UQM7	CAMK2A	S37	Y30S	30	Missense	distal	-7	no	4.979	4.813	EPSD	COSMIC	4.810	Down-regulation
CAMK_CAMK2_CAMK2A_ST	P35222	CTNNB1	Q9UQM7	CAMK2A	S37	L31M	31	Missense	distal	-6	no	4.979	4.843	EPSD	COSMIC	4.810	Down-regulation
CAMK_CAMK2_CAMK2A_ST	P35222	CTNNB1	Q9UQM7	CAMK2A	S37	A39V	39	Missense	proximal	2	no	4.979	4.964	EPSD	COSMIC	4.810	Down-regulation
CAMK_CAMK2_CAMK2A_ST	P35222	CTNNB1	Q9UQM7	CAMK2A	S37	L31Q	31	Missense	distal	-6	no	4.979	4.883	EPSD	COSMIC	4.810	Down-regulation
CAMK_CAMK2_CAMK2A_ST	P35222	CTNNB1	Q9UQM7	CAMK2A	S37	G34D	34	Missense	distal	-3	no	4.979	4.513	EPSD	COSMIC	4.810	Loss
CAMK_CAMK2_CAMK2A_ST	P35222	CTNNB1	Q9UQM7	CAMK2A	S37	I35K	35	Missense	proximal	-2	no	4.979	5.294	EPSD	COSMIC	4.810	Up-regulation
CAMK_CAMK2_CAMK2A_ST	P35222	CTNNB1	Q9UQM7	CAMK2A	S37	D32F	32	Missense	distal	-5	no	4.979	4.945	EPSD	COSMIC	4.810	Down-regulation
CAMK_CAMK2_CAMK2A_ST	P35222	CTNNB1	Q9UQM7	CAMK2A	S37	G38X	38	Missense	proximal	1	no	4.979	5.214	EPSD	COSMIC	4.810	Up-regulation
CAMK_CAMK2_CAMK2A_ST	P35222	CTNNB1	Q9UQM7	CAMK2A	S37	D32X	32	Missense	distal	-5	no	4.979	4.917	EPSD	COSMIC	4.810	Down-regulation
CAMK_CAMK2_CAMK2A_ST	P35222	CTNNB1	Q9UQM7	CAMK2A	S37	S33K	33	Missense	distal	-4	no	4.979	4.919	EPSD	COSMIC	4.810	Down-regulation
CAMK_CAMK2_CAMK2A_ST	P35222	CTNNB1	Q9UQM7	CAMK2A	S37	I35V	35	Missense	proximal	-2	no	4.979	4.736	EPSD	COSMIC	4.810	Loss
CAMK_CAMK2_CAMK2A_ST	P35222	CTNNB1	Q9UQM7	CAMK2A	S37	G34C	34	Missense	distal	-3	no	4.979	3.996	EPSD	COSMIC	4.810	Loss
CAMK_CAMK2_CAMK2A_ST	P35222	CTNNB1	Q9UQM7	CAMK2A	S37	G38S	38	Missense	proximal	1	no	4.979	5.477	EPSD	COSMIC	4.810	Up-regulation
CAMK_CAMK2_CAMK2A_ST	P35222	CTNNB1	Q9UQM7	CAMK2A	S37	S37V	37	Missense	central	0	yes	4.979	0.000	EPSD	COSMIC	4.810	Loss
CAMK_CAMK2_CAMK2A_ST	P35222	CTNNB1	Q9UQM7	CAMK2A	S37	P44I	44	Missense	distal	7	no	4.979	5.070	EPSD	COSMIC	4.810	Up-regulation
CAMK_CAMK2_CAMK2A_ST	P35222	CTNNB1	Q9UQM7	CAMK2A	S37	I35F	35	Missense	proximal	-2	no	4.979	4.261	EPSD	COSMIC	4.810	Loss
CAMK_CAMK2_CAMK2A_ST	P35222	CTNNB1	Q9UQM7	CAMK2A	S37	T40P	40	Missense	distal	3	no	4.979	4.902	EPSD	COSMIC	4.810	Down-regulation
CAMK_CAMK2_CAMK2A_ST	P35222	CTNNB1	Q9UQM7	CAMK2A	S45	T42R	42	Missense	distal	-3	no	2.148	7.204	EPSD	COSMIC	4.810	Gain
CAMK_CAMK2_CAMK2A_ST	P35222	CTNNB1	Q9UQM7	CAMK2A	S45	T42K	42	Missense	distal	-3	no	2.148	4.936	EPSD	COSMIC	4.810	Gain
CAMK_CAMK2_CAMK2A_ST	P35222	CTNNB1	Q9UQM7	CAMK2A	S179	H176R	176	Missense	distal	-3	no	1.954	7.452	EPSD	COSMIC	4.810	Gain
CAMK_CAMK2_CAMK2A_ST	P35222	CTNNB1	Q9UQM7	CAMK2A	S184	A187T	187	Missense	distal	3	no	5.549	5.313	EPSD	COSMIC	4.810	Down-regulation
CAMK_CAMK2_CAMK2A_ST	P35222	CTNNB1	Q9UQM7	CAMK2A	S184	R190C	190	Missense	distal	6	no	5.549	5.384	EPSD	COSMIC	4.810	Down-regulation
CAMK_CAMK2_CAMK2A_ST	P35222	CTNNB1	Q9UQM7	CAMK2A	S184	A187D	187	Missense	distal	3	no	5.549	5.522	EPSD	COSMIC	4.810	Down-regulation
CAMK_CAMK2_CAMK2A_ST	P35222	CTNNB1	Q9UQM7	CAMK2A	S184	A183S	183	Missense	proximal	-1	no	5.549	5.494	EPSD	COSMIC	4.810	Down-regulation
CAMK_CAMK2_CAMK2A_ST	P35222	CTNNB1	Q9UQM7	CAMK2A	S184	Q177P	177	Missense	distal	-7	no	5.549	5.653	EPSD	COSMIC	4.810	Up-regulation
CAMK_CAMK2_CAMK2A_ST	P35222	CTNNB1	Q9UQM7	CAMK2A	S184	A183T	183	Missense	proximal	-1	no	5.549	5.333	EPSD	COSMIC	4.810	Down-regulation
CAMK_CAMK2_CAMK2A_ST	P35222	CTNNB1	Q9UQM7	CAMK2A	S184	I188M	188	Missense	distal	4	no	5.549	5.686	EPSD	COSMIC	4.810	Up-regulation
CAMK_CAMK2_CAMK2A_ST	P35222	CTNNB1	Q9UQM7	CAMK2A	S184	R190H	190	Missense	distal	6	no	5.549	5.524	EPSD	COSMIC	4.810	Down-regulation
CAMK_CAMK2_CAMK2A_ST	P35222	CTNNB1	Q9UQM7	CAMK2A	S184	A187V	187	Missense	distal	3	no	5.549	5.487	EPSD	COSMIC	4.810	Down-regulation
CAMK_CAMK2_CAMK2A_ST	P35222	CTNNB1	Q9UQM7	CAMK2A	S184	E182D	182	Missense	proximal	-2	no	5.549	5.243	EPSD	COSMIC	4.810	Down-regulation
CAMK_CAMK2_CAMK2A_ST	P35222	CTNNB1	Q9UQM7	CAMK2A	S184	R185K	185	Missense	proximal	1	no	5.549	5.566	EPSD	COSMIC	4.810	Up-regulation
CAMK_CAMK2_CAMK2A_ST	P35222	CTNNB1	Q9UQM7	CAMK2A	S191	P192S	192	Missense	proximal	1	no	4.632	4.999	EPSD	COSMIC	4.810	Gain
CAMK_CAMK2_CAMK2A_ST	P35222	CTNNB1	Q9UQM7	CAMK2A	S191	P192H	192	Missense	proximal	1	no	4.632	5.325	EPSD	COSMIC	4.810	Gain
CAMK_CAMK2_CAMK2A_ST	P35222	CTNNB1	Q9UQM7	CAMK2A	T332	V325I	325	Missense	distal	-7	no	6.811	6.782	EPSD;PhosphoSitePlus	COSMIC	4.810	Down-regulation
CAMK_CAMK2_CAMK2A_ST	P35222	CTNNB1	Q9UQM7	CAMK2A	T332	L336V	336	Missense	distal	4	no	6.811	6.913	EPSD;PhosphoSitePlus	COSMIC	4.810	Up-regulation
CAMK_CAMK2_CAMK2A_ST	P35222	CTNNB1	Q9UQM7	CAMK2A	T332	I327T	327	Missense	distal	-5	no	6.811	7.009	EPSD;PhosphoSitePlus	COSMIC	4.810	Up-regulation
CAMK_CAMK2_CAMK2A_ST	P35222	CTNNB1	Q9UQM7	CAMK2A	T332	I327V	327	Missense	distal	-5	no	6.811	6.897	EPSD;PhosphoSitePlus	COSMIC	4.810	Up-regulation
CAMK_CAMK2_CAMK2A_ST	P35222	CTNNB1	Q9UQM7	CAMK2A	T332	K335R	335	Missense	distal	3	no	6.811	6.745	EPSD;PhosphoSitePlus	COSMIC	4.810	Down-regulation
CAMK_CAMK2_CAMK2A_ST	P35222	CTNNB1	Q9UQM7	CAMK2A	T332	K335Q	335	Missense	distal	3	no	6.811	6.768	EPSD;PhosphoSitePlus	COSMIC	4.810	Down-regulation
CAMK_CAMK2_CAMK2A_ST	P35222	CTNNB1	Q9UQM7	CAMK2A	T332	L337P	337	Missense	distal	5	no	6.811	6.870	EPSD;PhosphoSitePlus	COSMIC	4.810	Up-regulation
CAMK_CAMK2_CAMK2A_ST	P35222	CTNNB1	Q9UQM7	CAMK2A	T472	E479K	479	Missense	distal	7	no	6.656	6.866	EPSD;PhosphoSitePlus	COSMIC	4.810	Up-regulation
CAMK_CAMK2_CAMK2A_ST	P35222	CTNNB1	Q9UQM7	CAMK2A	T472	L468V	468	Missense	distal	-4	no	6.656	6.673	EPSD;PhosphoSitePlus	COSMIC	4.810	Up-regulation
CAMK_CAMK2_CAMK2A_ST	P35222	CTNNB1	Q9UQM7	CAMK2A	T472	A478T	478	Missense	distal	6	no	6.656	6.567	EPSD;PhosphoSitePlus	COSMIC	4.810	Down-regulation
CAMK_CAMK2_CAMK2A_ST	P35222	CTNNB1	Q9UQM7	CAMK2A	T472	H475Q	475	Missense	distal	3	no	6.656	6.624	EPSD;PhosphoSitePlus	COSMIC	4.810	Down-regulation
CAMK_CAMK2_CAMK2A_ST	P35222	CTNNB1	Q9UQM7	CAMK2A	T472	L471Q	471	Missense	proximal	-1	no	6.656	7.023	EPSD;PhosphoSitePlus	COSMIC	4.810	Up-regulation
CAMK_CAMK2_CAMK2A_ST	P35222	CTNNB1	Q9UQM7	CAMK2A	T472	R469C	469	Missense	distal	-3	no	6.656	1.075	EPSD;PhosphoSitePlus	COSMIC	4.810	Loss
CAMK_CAMK2_CAMK2A_ST	P35222	CTNNB1	Q9UQM7	CAMK2A	T472	A478G	478	Missense	distal	6	no	6.656	6.554	EPSD;PhosphoSitePlus	COSMIC	4.810	Down-regulation
CAMK_CAMK2_CAMK2A_ST	P35222	CTNNB1	Q9UQM7	CAMK2A	S552	T551K	551	Missense	proximal	-1	no	8.308	8.531	PhosphoSitePlus;EPSD	COSMIC	4.810	Up-regulation
CAMK_CAMK2_CAMK2A_ST	P35222	CTNNB1	Q9UQM7	CAMK2A	S552	R549C	549	Missense	distal	-3	no	8.308	2.727	PhosphoSitePlus;EPSD	COSMIC	4.810	Loss
CAMK_CAMK2_CAMK2A_ST	P35222	CTNNB1	Q9UQM7	CAMK2A	S552	Q545K	545	Missense	distal	-7	no	8.308	8.185	PhosphoSitePlus;EPSD	COSMIC	4.810	Down-regulation
CAMK_CAMK2_CAMK2A_ST	P35222	CTNNB1	Q9UQM7	CAMK2A	S552	Q558H	558	Missense	distal	6	no	8.308	8.276	PhosphoSitePlus;EPSD	COSMIC	4.810	Down-regulation
CAMK_CAMK2_CAMK2A_ST	P35222	CTNNB1	Q9UQM7	CAMK2A	S552	G555A	555	Missense	distal	3	no	8.308	8.498	PhosphoSitePlus;EPSD	COSMIC	4.810	Up-regulation
CAMK_CAMK2_CAMK2A_ST	P35222	CTNNB1	Q9UQM7	CAMK2A	S552	R550H	550	Missense	proximal	-2	no	8.308	8.187	PhosphoSitePlus;EPSD	COSMIC	4.810	Down-regulation
CAMK_CAMK2_CAMK2A_ST	P35222	CTNNB1	Q9UQM7	CAMK2A	S552	R550L	550	Missense	proximal	-2	no	8.308	8.134	PhosphoSitePlus;EPSD	COSMIC	4.810	Down-regulation
CAMK_CAMK2_CAMK2A_ST	P35222	CTNNB1	Q9UQM7	CAMK2A	S552	D546E	546	Missense	distal	-6	no	8.308	8.111	PhosphoSitePlus;EPSD	COSMIC	4.810	Down-regulation
CAMK_CAMK2_CAMK2A_ST	P35222	CTNNB1	Q9UQM7	CAMK2A	S552	S552F	552	Missense	central	0	yes	8.308	0.000	PhosphoSitePlus;EPSD	COSMIC	4.810	Loss
CAMK_CAMK2_CAMK2A_ST	P35222	CTNNB1	Q9UQM7	CAMK2A	S552	T547S	547	Missense	distal	-5	no	8.308	8.310	PhosphoSitePlus;EPSD	COSMIC	4.810	Up-regulation
CAMK_CAMK2_CAMK2A_ST	P35222	CTNNB1	Q9UQM7	CAMK2A	S552	G554D	554	Missense	proximal	2	no	8.308	10.142	PhosphoSitePlus;EPSD	COSMIC	4.810	Up-regulation
CAMK_CAMK2_CAMK2A_ST	P35222	CTNNB1	Q9UQM7	CAMK2A	S552	R550Q	550	Missense	proximal	-2	no	8.308	8.525	PhosphoSitePlus;EPSD	COSMIC	4.810	Up-regulation
CAMK_CAMK2_CAMK2A_ST	P35222	CTNNB1	Q9UQM7	CAMK2A	S552	T551I	551	Missense	proximal	-1	no	8.308	8.294	PhosphoSitePlus;EPSD	COSMIC	4.810	Down-regulation
CAMK_CAMK2_CAMK2A_ST	P35222	CTNNB1	Q9UQM7	CAMK2A	S675	R673W	673	Missense	proximal	-2	no	6.091	5.273	EPSD	COSMIC	4.810	Down-regulation
CAMK_CAMK2_CAMK2A_ST	P35222	CTNNB1	Q9UQM7	CAMK2A	S675	S680I	680	Missense	distal	5	no	6.091	5.822	EPSD	COSMIC	4.810	Down-regulation
CAMK_CAMK2_CAMK2A_ST	P35222	CTNNB1	Q9UQM7	CAMK2A	S675	E677D	677	Missense	proximal	2	no	6.091	7.008	EPSD	COSMIC	4.810	Up-regulation
CAMK_CAMK2_CAMK2A_ST	P35222	CTNNB1	Q9UQM7	CAMK2A	S675	R673H	673	Missense	proximal	-2	no	6.091	5.971	EPSD	COSMIC	4.810	Down-regulation
CAMK_CAMK2_CAMK2A_ST	P35222	CTNNB1	Q9UQM7	CAMK2A	S675	L678F	678	Missense	distal	3	no	6.091	6.026	EPSD	COSMIC	4.810	Down-regulation
CAMK_CAMK2_CAMK2A_ST	P35222	CTNNB1	Q9UQM7	CAMK2A	S675	R673C	673	Missense	proximal	-2	no	6.091	5.288	EPSD	COSMIC	4.810	Down-regulation
CAMK_CAMK2_CAMK2A_ST	O14490	DLGAP1	Q9UQM7	CAMK2A	T76	Y75C	75	Missense	proximal	-1	no	6.832	6.552	EPSD	COSMIC	4.810	Down-regulation
CAMK_CAMK2_CAMK2A_ST	O14490	DLGAP1	Q9UQM7	CAMK2A	T76	T69M	69	Missense	distal	-7	no	6.832	6.701	EPSD	COSMIC	4.810	Down-regulation
CAMK_CAMK2_CAMK2A_ST	O14490	DLGAP1	Q9UQM7	CAMK2A	S134	G136S	136	Missense	proximal	2	no	7.707	7.701	EPSD	COSMIC	4.810	Down-regulation
CAMK_CAMK2_CAMK2A_ST	O14490	DLGAP1	Q9UQM7	CAMK2A	S134	V128M	128	Missense	distal	-6	no	7.707	7.585	EPSD	COSMIC	4.810	Down-regulation
CAMK_CAMK2_CAMK2A_ST	O14490	DLGAP1	Q9UQM7	CAMK2A	S134	D133N	133	Missense	proximal	-1	no	7.707	7.751	EPSD	COSMIC	4.810	Up-regulation
CAMK_CAMK2_CAMK2A_ST	O14490	DLGAP1	Q9UQM7	CAMK2A	S134	R137C	137	Missense	distal	3	no	7.707	7.444	EPSD	COSMIC	4.810	Down-regulation
CAMK_CAMK2_CAMK2A_ST	O14490	DLGAP1	Q9UQM7	CAMK2A	S134	S132I	132	Missense	proximal	-2	no	7.707	7.639	EPSD	COSMIC	4.810	Down-regulation
CAMK_CAMK2_CAMK2A_ST	O14490	DLGAP1	Q9UQM7	CAMK2A	S134	R131H	131	Missense	distal	-3	no	7.707	2.210	EPSD	COSMIC	4.810	Loss
CAMK_CAMK2_CAMK2A_ST	O14490	DLGAP1	Q9UQM7	CAMK2A	S134	D133G	133	Missense	proximal	-1	no	7.707	7.741	EPSD	COSMIC	4.810	Up-regulation
CAMK_CAMK2_CAMK2A_ST	O14490	DLGAP1	Q9UQM7	CAMK2A	S134	D133E	133	Missense	proximal	-1	no	7.707	8.131	EPSD	COSMIC	4.810	Up-regulation
CAMK_CAMK2_CAMK2A_ST	O14490	DLGAP1	Q9UQM7	CAMK2A	S169	G165E	165	Missense	distal	-4	no	4.624	4.889	EPSD	COSMIC	4.810	Gain
CAMK_CAMK2_CAMK2A_ST	O14490	DLGAP1	Q9UQM7	CAMK2A	S233	L237M	237	Missense	distal	4	no	6.191	6.274	EPSD	COSMIC	4.810	Up-regulation
CAMK_CAMK2_CAMK2A_ST	O14490	DLGAP1	Q9UQM7	CAMK2A	S233	Q234H	234	Missense	proximal	1	no	6.191	6.731	EPSD	COSMIC	4.810	Up-regulation
CAMK_CAMK2_CAMK2A_ST	O14490	DLGAP1	Q9UQM7	CAMK2A	S233	D229N	229	Missense	distal	-4	no	6.191	6.254	EPSD	COSMIC	4.810	Up-regulation
CAMK_CAMK2_CAMK2A_ST	O14490	DLGAP1	Q9UQM7	CAMK2A	S233	P228S	228	Missense	distal	-5	no	6.191	6.189	EPSD	COSMIC	4.810	Down-regulation
CAMK_CAMK2_CAMK2A_ST	O14490	DLGAP1	Q9UQM7	CAMK2A	S233	R230L	230	Missense	distal	-3	no	6.191	1.068	EPSD	COSMIC;GDSC;CCLE	4.810	Loss
CAMK_CAMK2_CAMK2A_ST	O14490	DLGAP1	Q9UQM7	CAMK2A	S233	R230H	230	Missense	distal	-3	no	6.191	0.693	EPSD	COSMIC	4.810	Loss
CAMK_CAMK2_CAMK2A_ST	O14490	DLGAP1	Q9UQM7	CAMK2A	S233	S231F	231	Missense	proximal	-2	no	6.191	5.405	EPSD	COSMIC	4.810	Down-regulation
CAMK_CAMK2_CAMK2A_ST	O14490	DLGAP1	Q9UQM7	CAMK2A	S233	R226H	226	Missense	distal	-7	no	6.191	6.131	EPSD	COSMIC	4.810	Down-regulation
CAMK_CAMK2_CAMK2A_ST	O14490	DLGAP1	Q9UQM7	CAMK2A	S233	R226L	226	Missense	distal	-7	no	6.191	6.318	EPSD	COSMIC	4.810	Up-regulation
CAMK_CAMK2_CAMK2A_ST	O14490	DLGAP1	Q9UQM7	CAMK2A	S280	S277R	277	Missense	distal	-3	no	2.041	6.501	EPSD	COSMIC	4.810	Gain
CAMK_CAMK2_CAMK2A_ST	O14490	DLGAP1	Q9UQM7	CAMK2A	S346	R343W	343	Missense	distal	-3	no	6.665	-5.355	EPSD	COSMIC	4.810	Loss
CAMK_CAMK2_CAMK2A_ST	O14490	DLGAP1	Q9UQM7	CAMK2A	S346	G345V	345	Missense	proximal	-1	no	6.665	6.642	EPSD	COSMIC	4.810	Down-regulation
CAMK_CAMK2_CAMK2A_ST	O14490	DLGAP1	Q9UQM7	CAMK2A	S346	K349E	349	Missense	distal	3	no	6.665	6.830	EPSD	COSMIC	4.810	Up-regulation
CAMK_CAMK2_CAMK2A_ST	O14490	DLGAP1	Q9UQM7	CAMK2A	S346	R340Q	340	Missense	distal	-6	no	6.665	6.668	EPSD	COSMIC	4.810	Up-regulation
CAMK_CAMK2_CAMK2A_ST	O14490	DLGAP1	Q9UQM7	CAMK2A	S346	D353G	353	Missense	distal	7	no	6.665	6.695	EPSD	COSMIC	4.810	Up-regulation
CAMK_CAMK2_CAMK2A_ST	O14490	DLGAP1	Q9UQM7	CAMK2A	S346	D353Y	353	Missense	distal	7	no	6.665	6.774	EPSD	COSMIC	4.810	Up-regulation
CAMK_CAMK2_CAMK2A_ST	O14490	DLGAP1	Q9UQM7	CAMK2A	S375	A371V	371	Missense	distal	-4	no	7.065	6.775	EPSD	COSMIC;GDSC;CCLE	4.810	Down-regulation
CAMK_CAMK2_CAMK2A_ST	O14490	DLGAP1	Q9UQM7	CAMK2A	S375	L377F	377	Missense	proximal	2	no	7.065	6.127	EPSD	COSMIC	4.810	Down-regulation
CAMK_CAMK2_CAMK2A_ST	O14490	DLGAP1	Q9UQM7	CAMK2A	S375	E374D	374	Missense	proximal	-1	no	7.065	6.640	EPSD	COSMIC	4.810	Down-regulation
CAMK_CAMK2_CAMK2A_ST	O14490	DLGAP1	Q9UQM7	CAMK2A	S406	R403Q	403	Missense	distal	-3	no	6.305	2.734	EPSD	COSMIC;GDSC;CCLE	4.810	Loss
CAMK_CAMK2_CAMK2A_ST	O14490	DLGAP1	Q9UQM7	CAMK2A	S406	R403W	403	Missense	distal	-3	no	6.305	-5.715	EPSD	COSMIC	4.810	Loss
CAMK_CAMK2_CAMK2A_ST	O14490	DLGAP1	Q9UQM7	CAMK2A	S406	R403L	403	Missense	distal	-3	no	6.305	1.183	EPSD	COSMIC	4.810	Loss
CAMK_CAMK2_CAMK2A_ST	O14490	DLGAP1	Q9UQM7	CAMK2A	S406	R409S	409	Missense	distal	3	no	6.305	6.400	EPSD	COSMIC	4.810	Up-regulation
CAMK_CAMK2_CAMK2A_ST	O14490	DLGAP1	Q9UQM7	CAMK2A	S406	L400R	400	Missense	distal	-6	no	6.305	6.206	EPSD	COSMIC	4.810	Down-regulation
CAMK_CAMK2_CAMK2A_ST	O14490	DLGAP1	Q9UQM7	CAMK2A	S412	S419I	419	Missense	distal	7	no	5.527	5.717	EPSD	COSMIC	4.810	Up-regulation
CAMK_CAMK2_CAMK2A_ST	O14490	DLGAP1	Q9UQM7	CAMK2A	S412	R409S	409	Missense	distal	-3	no	5.527	1.066	EPSD	COSMIC	4.810	Loss
CAMK_CAMK2_CAMK2A_ST	O14490	DLGAP1	Q9UQM7	CAMK2A	S412	S419N	419	Missense	distal	7	no	5.527	5.573	EPSD	COSMIC	4.810	Up-regulation
CAMK_CAMK2_CAMK2A_ST	O14490	DLGAP1	Q9UQM7	CAMK2A	S412	S419L	419	Missense	distal	7	no	5.527	5.690	EPSD	COSMIC	4.810	Up-regulation
CAMK_CAMK2_CAMK2A_ST	O14490	DLGAP1	Q9UQM7	CAMK2A	S419	S419I	419	Missense	central	0	yes	6.360	0.000	EPSD	COSMIC	4.810	Loss
CAMK_CAMK2_CAMK2A_ST	O14490	DLGAP1	Q9UQM7	CAMK2A	S419	D421G	421	Missense	proximal	2	no	6.360	4.525	EPSD	COSMIC	4.810	Loss
CAMK_CAMK2_CAMK2A_ST	O14490	DLGAP1	Q9UQM7	CAMK2A	S419	D421E	421	Missense	proximal	2	no	6.360	5.443	EPSD	COSMIC	4.810	Down-regulation
CAMK_CAMK2_CAMK2A_ST	O14490	DLGAP1	Q9UQM7	CAMK2A	S419	L423P	423	Missense	distal	4	no	6.360	6.397	EPSD	COSMIC	4.810	Up-regulation
CAMK_CAMK2_CAMK2A_ST	O14490	DLGAP1	Q9UQM7	CAMK2A	S419	S419N	419	Missense	central	0	yes	6.360	0.000	EPSD	COSMIC	4.810	Loss
CAMK_CAMK2_CAMK2A_ST	O14490	DLGAP1	Q9UQM7	CAMK2A	S419	S419L	419	Missense	central	0	yes	6.360	0.000	EPSD	COSMIC	4.810	Loss
CAMK_CAMK2_CAMK2A_ST	O14490	DLGAP1	Q9UQM7	CAMK2A	S440	R435C	435	Missense	distal	-5	no	6.888	6.887	EPSD	COSMIC	4.810	Down-regulation
CAMK_CAMK2_CAMK2A_ST	O14490	DLGAP1	Q9UQM7	CAMK2A	S491	R496W	496	Missense	distal	5	no	7.188	6.812	EPSD	COSMIC;GDSC;CCLE	4.810	Down-regulation
CAMK_CAMK2_CAMK2A_ST	O14490	DLGAP1	Q9UQM7	CAMK2A	S491	G485V	485	Missense	distal	-6	no	7.188	7.135	EPSD	COSMIC	4.810	Down-regulation
CAMK_CAMK2_CAMK2A_ST	O14490	DLGAP1	Q9UQM7	CAMK2A	S491	V495L	495	Missense	distal	4	no	7.188	7.085	EPSD	COSMIC	4.810	Down-regulation
CAMK_CAMK2_CAMK2A_ST	O14490	DLGAP1	Q9UQM7	CAMK2A	S491	R496Q	496	Missense	distal	5	no	7.188	7.187	EPSD	COSMIC	4.810	Down-regulation
CAMK_CAMK2_CAMK2A_ST	O14490	DLGAP1	Q9UQM7	CAMK2A	S491	I498T	498	Missense	distal	7	no	7.188	7.092	EPSD	COSMIC	4.810	Down-regulation
CAMK_CAMK2_CAMK2A_ST	O14490	DLGAP1	Q9UQM7	CAMK2A	S491	R488Q	488	Missense	distal	-3	no	7.188	3.616	EPSD	COSMIC	4.810	Loss
CAMK_CAMK2_CAMK2A_ST	O14490	DLGAP1	Q9UQM7	CAMK2A	S491	R490H	490	Missense	proximal	-1	no	7.188	7.333	EPSD	COSMIC	4.810	Up-regulation
CAMK_CAMK2_CAMK2A_ST	O14490	DLGAP1	Q9UQM7	CAMK2A	S491	R490S	490	Missense	proximal	-1	no	7.188	7.276	EPSD	COSMIC	4.810	Up-regulation
CAMK_CAMK2_CAMK2A_ST	O14490	DLGAP1	Q9UQM7	CAMK2A	S491	P484H	484	Missense	distal	-7	no	7.188	6.967	EPSD	COSMIC	4.810	Down-regulation
CAMK_CAMK2_CAMK2A_ST	O14490	DLGAP1	Q9UQM7	CAMK2A	S491	R496S	496	Missense	distal	5	no	7.188	7.329	EPSD	COSMIC	4.810	Up-regulation
CAMK_CAMK2_CAMK2A_ST	O14490	DLGAP1	Q9UQM7	CAMK2A	S491	R496H	496	Missense	distal	5	no	7.188	7.301	EPSD	COSMIC	4.810	Up-regulation
CAMK_CAMK2_CAMK2A_ST	O14490	DLGAP1	Q9UQM7	CAMK2A	S493	R496W	496	Missense	distal	3	no	7.165	6.613	EPSD	COSMIC;GDSC;CCLE	4.810	Down-regulation
CAMK_CAMK2_CAMK2A_ST	O14490	DLGAP1	Q9UQM7	CAMK2A	S493	V495L	495	Missense	proximal	2	no	7.165	6.827	EPSD	COSMIC	4.810	Down-regulation
CAMK_CAMK2_CAMK2A_ST	O14490	DLGAP1	Q9UQM7	CAMK2A	S493	R496Q	496	Missense	distal	3	no	7.165	7.187	EPSD	COSMIC	4.810	Up-regulation
CAMK_CAMK2_CAMK2A_ST	O14490	DLGAP1	Q9UQM7	CAMK2A	S493	I498T	498	Missense	distal	5	no	7.165	7.273	EPSD	COSMIC	4.810	Up-regulation
CAMK_CAMK2_CAMK2A_ST	O14490	DLGAP1	Q9UQM7	CAMK2A	S493	E499A	499	Missense	distal	6	no	7.165	7.187	EPSD	COSMIC	4.810	Up-regulation
CAMK_CAMK2_CAMK2A_ST	O14490	DLGAP1	Q9UQM7	CAMK2A	S493	R488Q	488	Missense	distal	-5	no	7.165	7.068	EPSD	COSMIC	4.810	Down-regulation
CAMK_CAMK2_CAMK2A_ST	O14490	DLGAP1	Q9UQM7	CAMK2A	S493	R490H	490	Missense	distal	-3	no	7.165	1.667	EPSD	COSMIC	4.810	Loss
CAMK_CAMK2_CAMK2A_ST	O14490	DLGAP1	Q9UQM7	CAMK2A	S493	R490S	490	Missense	distal	-3	no	7.165	2.704	EPSD	COSMIC	4.810	Loss
CAMK_CAMK2_CAMK2A_ST	O14490	DLGAP1	Q9UQM7	CAMK2A	S493	R496S	496	Missense	distal	3	no	7.165	7.259	EPSD	COSMIC	4.810	Up-regulation
CAMK_CAMK2_CAMK2A_ST	O14490	DLGAP1	Q9UQM7	CAMK2A	S493	R496H	496	Missense	distal	3	no	7.165	7.219	EPSD	COSMIC	4.810	Up-regulation
CAMK_CAMK2_CAMK2A_ST	O14490	DLGAP1	Q9UQM7	CAMK2A	S503	R496W	496	Missense	distal	-7	no	5.870	6.614	EPSD	COSMIC;GDSC;CCLE	4.810	Up-regulation
CAMK_CAMK2_CAMK2A_ST	O14490	DLGAP1	Q9UQM7	CAMK2A	S503	S510F	510	Missense	distal	7	no	5.870	6.115	EPSD	COSMIC	4.810	Up-regulation
CAMK_CAMK2_CAMK2A_ST	O14490	DLGAP1	Q9UQM7	CAMK2A	S503	R496Q	496	Missense	distal	-7	no	5.870	5.927	EPSD	COSMIC	4.810	Up-regulation
CAMK_CAMK2_CAMK2A_ST	O14490	DLGAP1	Q9UQM7	CAMK2A	S503	I498T	498	Missense	distal	-5	no	5.870	6.068	EPSD	COSMIC	4.810	Up-regulation
CAMK_CAMK2_CAMK2A_ST	O14490	DLGAP1	Q9UQM7	CAMK2A	S503	E499A	499	Missense	distal	-4	no	5.870	5.890	EPSD	COSMIC	4.810	Up-regulation
CAMK_CAMK2_CAMK2A_ST	O14490	DLGAP1	Q9UQM7	CAMK2A	S503	R496S	496	Missense	distal	-7	no	5.870	5.902	EPSD	COSMIC	4.810	Up-regulation
CAMK_CAMK2_CAMK2A_ST	O14490	DLGAP1	Q9UQM7	CAMK2A	S503	R496H	496	Missense	distal	-7	no	5.870	5.810	EPSD	COSMIC	4.810	Down-regulation
CAMK_CAMK2_CAMK2A_ST	O14490	DLGAP1	Q9UQM7	CAMK2A	S515	P516S	516	Missense	proximal	1	no	7.871	8.238	EPSD	COSMIC	4.810	Up-regulation
CAMK_CAMK2_CAMK2A_ST	O14490	DLGAP1	Q9UQM7	CAMK2A	S515	R518L	518	Missense	distal	3	no	7.871	7.653	EPSD	COSMIC	4.810	Down-regulation
CAMK_CAMK2_CAMK2A_ST	O14490	DLGAP1	Q9UQM7	CAMK2A	S515	S510F	510	Missense	distal	-5	no	7.871	7.888	EPSD	COSMIC	4.810	Up-regulation
CAMK_CAMK2_CAMK2A_ST	O14490	DLGAP1	Q9UQM7	CAMK2A	S515	R518H	518	Missense	distal	3	no	7.871	7.925	EPSD	COSMIC	4.810	Up-regulation
CAMK_CAMK2_CAMK2A_ST	O14490	DLGAP1	Q9UQM7	CAMK2A	S515	R512S	512	Missense	distal	-3	no	7.871	3.410	EPSD	COSMIC	4.810	Loss
CAMK_CAMK2_CAMK2A_ST	O14490	DLGAP1	Q9UQM7	CAMK2A	S515	R512H	512	Missense	distal	-3	no	7.871	2.373	EPSD	COSMIC	4.810	Loss
CAMK_CAMK2_CAMK2A_ST	O14490	DLGAP1	Q9UQM7	CAMK2A	S562	A569V	569	Missense	distal	7	no	5.265	5.295	EPSD	COSMIC	4.810	Up-regulation
CAMK_CAMK2_CAMK2A_ST	O14490	DLGAP1	Q9UQM7	CAMK2A	S562	A559D	559	Missense	distal	-3	no	5.265	4.622	EPSD	COSMIC	4.810	Loss
CAMK_CAMK2_CAMK2A_ST	O14490	DLGAP1	Q9UQM7	CAMK2A	S562	A559G	559	Missense	distal	-3	no	5.265	5.087	EPSD	COSMIC	4.810	Down-regulation
CAMK_CAMK2_CAMK2A_ST	O14490	DLGAP1	Q9UQM7	CAMK2A	S592	T590I	590	Missense	proximal	-2	no	5.179	5.155	EPSD	COSMIC;GDSC	4.810	Down-regulation
CAMK_CAMK2_CAMK2A_ST	O14490	DLGAP1	Q9UQM7	CAMK2A	S592	M596I	596	Missense	distal	4	no	5.179	5.042	EPSD	COSMIC	4.810	Down-regulation
CAMK_CAMK2_CAMK2A_ST	O14490	DLGAP1	Q9UQM7	CAMK2A	S592	L586I	586	Missense	distal	-6	no	5.179	5.101	EPSD	COSMIC	4.810	Down-regulation
CAMK_CAMK2_CAMK2A_ST	O14490	DLGAP1	Q9UQM7	CAMK2A	S651	R648S	648	Missense	distal	-3	no	9.541	5.081	EPSD	COSMIC	4.810	Down-regulation
CAMK_CAMK2_CAMK2A_ST	O14490	DLGAP1	Q9UQM7	CAMK2A	S651	D657G	657	Missense	distal	6	no	9.541	9.452	EPSD	COSMIC	4.810	Down-regulation
CAMK_CAMK2_CAMK2A_ST	O14490	DLGAP1	Q9UQM7	CAMK2A	S651	Q655H	655	Missense	distal	4	no	9.541	9.484	EPSD	COSMIC	4.810	Down-regulation
CAMK_CAMK2_CAMK2A_ST	O14490	DLGAP1	Q9UQM7	CAMK2A	S651	S651F	651	Missense	central	0	yes	9.541	0.000	EPSD	COSMIC	4.810	Loss
CAMK_CAMK2_CAMK2A_ST	O14490	DLGAP1	Q9UQM7	CAMK2A	S695	T698K	698	Missense	distal	3	no	8.269	8.435	EPSD	COSMIC	4.810	Up-regulation
CAMK_CAMK2_CAMK2A_ST	O14490	DLGAP1	Q9UQM7	CAMK2A	S695	V700I	700	Missense	distal	5	no	8.269	8.166	EPSD	COSMIC	4.810	Down-regulation
CAMK_CAMK2_CAMK2A_ST	O14490	DLGAP1	Q9UQM7	CAMK2A	S695	A699E	699	Missense	distal	4	no	8.269	8.451	EPSD	COSMIC	4.810	Up-regulation
CAMK_CAMK2_CAMK2A_ST	O14490	DLGAP1	Q9UQM7	CAMK2A	S958	S962C	962	Missense	distal	4	no	8.147	7.783	EPSD	COSMIC	4.810	Down-regulation
CAMK_CAMK2_CAMK2A_ST	O14490	DLGAP1	Q9UQM7	CAMK2A	S958	E961K	961	Missense	distal	3	no	8.147	7.982	EPSD	COSMIC	4.810	Down-regulation
CAMK_CAMK2_CAMK2A_ST	O14490	DLGAP1	Q9UQM7	CAMK2A	S958	A951T	951	Missense	distal	-7	no	8.147	8.487	EPSD	COSMIC	4.810	Up-regulation
CAMK_CAMK2_CAMK2A_ST	O14490	DLGAP1	Q9UQM7	CAMK2A	S958	A963T	963	Missense	distal	5	no	8.147	7.934	EPSD	COSMIC	4.810	Down-regulation
CAMK_CAMK2_CAMK2A_ST	O14490	DLGAP1	Q9UQM7	CAMK2A	S962	E967K	967	Missense	distal	5	no	6.538	6.568	EPSD	COSMIC	4.810	Up-regulation
CAMK_CAMK2_CAMK2A_ST	O14490	DLGAP1	Q9UQM7	CAMK2A	S962	S962C	962	Missense	central	0	yes	6.538	0.000	EPSD	COSMIC	4.810	Loss
CAMK_CAMK2_CAMK2A_ST	O14490	DLGAP1	Q9UQM7	CAMK2A	S962	E961K	961	Missense	proximal	-1	no	6.538	6.357	EPSD	COSMIC	4.810	Down-regulation
CAMK_CAMK2_CAMK2A_ST	O14490	DLGAP1	Q9UQM7	CAMK2A	S962	A963T	963	Missense	proximal	1	no	6.538	6.637	EPSD	COSMIC	4.810	Up-regulation
CAMK_CAMK2_CAMK2A_ST	P09917	ALOX5	Q9UQM7	CAMK2A	T105	P99H	99	Missense	distal	-6	no	6.840	6.700	EPSD	COSMIC;GDSC;CCLE	4.810	Down-regulation
CAMK_CAMK2_CAMK2A_ST	P09917	ALOX5	Q9UQM7	CAMK2A	S272	L267M	267	Missense	distal	-5	no	11.464	11.469	EPSD;PhosphoSitePlus	COSMIC	4.810	Up-regulation
CAMK_CAMK2_CAMK2A_ST	P09917	ALOX5	Q9UQM7	CAMK2A	T486	A487D	487	Missense	proximal	1	no	6.904	6.692	EPSD	COSMIC	4.810	Down-regulation
CAMK_CAMK2_CAMK2A_ST	P09917	ALOX5	Q9UQM7	CAMK2A	S532	E538K	538	Missense	distal	6	no	5.900	5.849	EPSD	COSMIC	4.810	Down-regulation
CAMK_CAMK2_CAMK2A_ST	P41134	ID1	Q9UQM7	CAMK2A	S5	T10A	10	Missense	distal	5	no	4.710	4.922	EPSD	COSMIC;GDSC;CCLE	4.810	Gain
CAMK_CAMK2_CAMK2A_ST	P41134	ID1	Q9UQM7	CAMK2A	S5	S7R	7	Missense	proximal	2	no	4.710	5.135	EPSD	COSMIC;GDSC	4.810	Gain
CAMK_CAMK2_CAMK2A_ST	P55055	NR1H2	Q9UQM7	CAMK2A	S426	L421V	421	Missense	distal	-5	no	6.813	6.789	PhosphoSitePlus	COSMIC	4.810	Down-regulation
CAMK_CAMK2_CAMK2A_ST	P55055	NR1H2	Q9UQM7	CAMK2A	S426	R419H	419	Missense	distal	-7	no	6.813	6.753	PhosphoSitePlus	COSMIC	4.810	Down-regulation
CAMK_CAMK2_CAMK2A_ST	P55055	NR1H2	Q9UQM7	CAMK2A	S426	R428H	428	Missense	proximal	2	no	6.813	5.745	PhosphoSitePlus	COSMIC;CCLE	4.810	Down-regulation
CAMK_CAMK2_CAMK2A_ST	P51790	CLCN3	Q9UQM7	CAMK2A	S109	R106L	106	Missense	distal	-3	no	8.332	3.209	PhosphoSitePlus	COSMIC	4.810	Loss
CAMK_CAMK2_CAMK2A_ST	P51790	CLCN3	Q9UQM7	CAMK2A	S109	I107M	107	Missense	proximal	-2	no	8.332	8.583	PhosphoSitePlus	COSMIC;GDSC;CCLE	4.810	Up-regulation
CAMK_CAMK2_CAMK2A_ST	P51790	CLCN3	Q9UQM7	CAMK2A	T713	A707V	707	Missense	distal	-6	no	5.856	6.011	EPSD	COSMIC	4.810	Up-regulation
CAMK_CAMK2_CAMK2A_ST	P51790	CLCN3	Q9UQM7	CAMK2A	S745	P742R	742	Missense	distal	-3	no	4.040	8.957	EPSD	COSMIC	4.810	Gain
CAMK_CAMK2_CAMK2A_ST	P40189	IL6ST	Q9UQM7	CAMK2A	S782	E781K	781	Missense	proximal	-1	no	8.741	8.560	PhosphoSitePlus	COSMIC	4.810	Down-regulation
CAMK_CAMK2_CAMK2A_ST	P40189	IL6ST	Q9UQM7	CAMK2A	S824	I828V	828	Missense	distal	4	no	4.686	4.843	EPSD	COSMIC	4.810	Gain
CAMK_CAMK2_CAMK2A_ST	P40189	IL6ST	Q9UQM7	CAMK2A	S838	R833S	833	Missense	distal	-5	no	5.694	5.765	EPSD	COSMIC	4.810	Up-regulation
CAMK_CAMK2_CAMK2A_ST	P40189	IL6ST	Q9UQM7	CAMK2A	S838	E843G	843	Missense	distal	5	no	5.694	5.573	EPSD	COSMIC	4.810	Down-regulation
CAMK_CAMK2_CAMK2A_ST	P40189	IL6ST	Q9UQM7	CAMK2A	S838	D844E	844	Missense	distal	6	no	5.694	5.684	EPSD	COSMIC	4.810	Down-regulation
CAMK_CAMK2_CAMK2A_ST	P40189	IL6ST	Q9UQM7	CAMK2A	S838	E842K	842	Missense	distal	4	no	5.694	5.518	EPSD	COSMIC	4.810	Down-regulation
CAMK_CAMK2_CAMK2A_ST	P40189	IL6ST	Q9UQM7	CAMK2A	T890	V885I	885	Missense	distal	-5	no	7.308	7.222	EPSD	COSMIC	4.810	Down-regulation
CAMK_CAMK2_CAMK2A_ST	P40189	IL6ST	Q9UQM7	CAMK2A	T890	A896V	896	Missense	distal	6	no	7.308	7.144	EPSD	COSMIC;CCLE	4.810	Down-regulation
CAMK_CAMK2_CAMK2A_ST	P40189	IL6ST	Q9UQM7	CAMK2A	T890	R887S	887	Missense	distal	-3	no	7.308	2.847	EPSD	COSMIC	4.810	Loss
CAMK_CAMK2_CAMK2A_ST	Q00613	HSF1	Q9UQM7	CAMK2A	T120	T120A	120	Missense	central	0	yes	7.050	0.000	EPSD	COSMIC	4.810	Loss
CAMK_CAMK2_CAMK2A_ST	Q00613	HSF1	Q9UQM7	CAMK2A	S121	T120A	120	Missense	proximal	-1	no	5.278	5.493	EPSD	COSMIC	4.810	Up-regulation
CAMK_CAMK2_CAMK2A_ST	Q00613	HSF1	Q9UQM7	CAMK2A	S127	D129G	129	Missense	proximal	2	no	6.289	4.454	EPSD	COSMIC	4.810	Loss
CAMK_CAMK2_CAMK2A_ST	Q00613	HSF1	Q9UQM7	CAMK2A	S127	R133S	133	Missense	distal	6	no	6.289	6.287	EPSD	COSMIC	4.810	Down-regulation
CAMK_CAMK2_CAMK2A_ST	Q00613	HSF1	Q9UQM7	CAMK2A	S127	T120A	120	Missense	distal	-7	no	6.289	5.948	EPSD	COSMIC	4.810	Down-regulation
CAMK_CAMK2_CAMK2A_ST	Q00613	HSF1	Q9UQM7	CAMK2A	S136	D129G	129	Missense	distal	-7	no	8.581	8.669	EPSD	COSMIC	4.810	Up-regulation
CAMK_CAMK2_CAMK2A_ST	Q00613	HSF1	Q9UQM7	CAMK2A	S136	R133S	133	Missense	distal	-3	no	8.581	4.121	EPSD	COSMIC	4.810	Loss
CAMK_CAMK2_CAMK2A_ST	Q00613	HSF1	Q9UQM7	CAMK2A	S136	V137I	137	Missense	proximal	1	no	8.581	8.789	EPSD	COSMIC	4.810	Up-regulation
CAMK_CAMK2_CAMK2A_ST	Q00613	HSF1	Q9UQM7	CAMK2A	S136	K139N	139	Missense	distal	3	no	8.581	8.496	EPSD	COSMIC;GDSC;CCLE	4.810	Down-regulation
CAMK_CAMK2_CAMK2A_ST	Q00613	HSF1	Q9UQM7	CAMK2A	S230	R227Q	227	Missense	distal	-3	no	10.324	6.753	PhosphoSitePlus	COSMIC;GDSC	4.810	Down-regulation
CAMK_CAMK2_CAMK2A_ST	Q00613	HSF1	Q9UQM7	CAMK2A	S230	G236S	236	Missense	distal	6	no	10.324	10.383	PhosphoSitePlus	COSMIC;CCLE	4.810	Up-regulation
CAMK_CAMK2_CAMK2A_ST	Q00613	HSF1	Q9UQM7	CAMK2A	S230	S237L	237	Missense	distal	7	no	10.324	10.487	PhosphoSitePlus	COSMIC	4.810	Up-regulation
CAMK_CAMK2_CAMK2A_ST	Q00613	HSF1	Q9UQM7	CAMK2A	S283	S279F	279	Missense	distal	-4	no	6.199	5.681	EPSD	COSMIC	4.810	Down-regulation
CAMK_CAMK2_CAMK2A_ST	Q00613	HSF1	Q9UQM7	CAMK2A	S283	R287K	287	Missense	distal	4	no	6.199	6.325	EPSD	COSMIC	4.810	Up-regulation
CAMK_CAMK2_CAMK2A_ST	Q00613	HSF1	Q9UQM7	CAMK2A	S283	P280L	280	Missense	distal	-3	no	6.199	5.995	EPSD	COSMIC	4.810	Down-regulation
CAMK_CAMK2_CAMK2A_ST	Q00613	HSF1	Q9UQM7	CAMK2A	S283	G281S	281	Missense	proximal	-2	no	6.199	6.357	EPSD	COSMIC	4.810	Up-regulation
CAMK_CAMK2_CAMK2A_ST	Q00613	HSF1	Q9UQM7	CAMK2A	S283	S283N	283	Missense	central	0	yes	6.199	0.000	EPSD	COSMIC	4.810	Loss
CAMK_CAMK2_CAMK2A_ST	Q00613	HSF1	Q9UQM7	CAMK2A	S290	R287K	287	Missense	distal	-3	no	6.695	4.427	EPSD	COSMIC	4.810	Loss
CAMK_CAMK2_CAMK2A_ST	Q00613	HSF1	Q9UQM7	CAMK2A	S290	S283N	283	Missense	distal	-7	no	6.695	6.792	EPSD	COSMIC	4.810	Up-regulation
CAMK_CAMK2_CAMK2A_ST	Q00613	HSF1	Q9UQM7	CAMK2A	S320	P318T	318	Missense	proximal	-2	no	9.417	9.367	EPSD	COSMIC	4.810	Down-regulation
CAMK_CAMK2_CAMK2A_ST	Q00613	HSF1	Q9UQM7	CAMK2A	S320	P327Q	327	Missense	distal	7	no	9.417	9.304	EPSD	COSMIC	4.810	Down-regulation
CAMK_CAMK2_CAMK2A_ST	Q00613	HSF1	Q9UQM7	CAMK2A	T355	D356N	356	Missense	proximal	1	no	6.031	5.918	EPSD	COSMIC	4.810	Down-regulation
CAMK_CAMK2_CAMK2A_ST	Q00613	HSF1	Q9UQM7	CAMK2A	T355	T349M	349	Missense	distal	-6	no	6.031	5.880	EPSD	COSMIC	4.810	Down-regulation
CAMK_CAMK2_CAMK2A_ST	Q00613	HSF1	Q9UQM7	CAMK2A	T355	H354Y	354	Missense	proximal	-1	no	6.031	5.837	EPSD	COSMIC	4.810	Down-regulation
CAMK_CAMK2_CAMK2A_ST	Q00613	HSF1	Q9UQM7	CAMK2A	T355	E358K	358	Missense	distal	3	no	6.031	5.866	EPSD	COSMIC	4.810	Down-regulation
CAMK_CAMK2_CAMK2A_ST	Q00613	HSF1	Q9UQM7	CAMK2A	S363	S363P	363	Missense	central	0	yes	6.498	0.000	EPSD	COSMIC	4.810	Loss
CAMK_CAMK2_CAMK2A_ST	Q00613	HSF1	Q9UQM7	CAMK2A	S363	P365Q	365	Missense	proximal	2	no	6.498	6.769	EPSD	COSMIC	4.810	Up-regulation
CAMK_CAMK2_CAMK2A_ST	Q00613	HSF1	Q9UQM7	CAMK2A	S363	D356N	356	Missense	distal	-7	no	6.498	6.384	EPSD	COSMIC	4.810	Down-regulation
CAMK_CAMK2_CAMK2A_ST	Q00613	HSF1	Q9UQM7	CAMK2A	S363	P365T	365	Missense	proximal	2	no	6.498	6.349	EPSD	COSMIC	4.810	Down-regulation
CAMK_CAMK2_CAMK2A_ST	Q00613	HSF1	Q9UQM7	CAMK2A	S363	E358K	358	Missense	distal	-5	no	6.498	6.495	EPSD	COSMIC	4.810	Down-regulation
CAMK_CAMK2_CAMK2A_ST	Q00613	HSF1	Q9UQM7	CAMK2A	S363	P365L	365	Missense	proximal	2	no	6.498	6.662	EPSD	COSMIC	4.810	Up-regulation
CAMK_CAMK2_CAMK2A_ST	Q00613	HSF1	Q9UQM7	CAMK2A	S458	P452H	452	Missense	distal	-6	no	4.973	4.833	EPSD	COSMIC	4.810	Down-regulation
CAMK_CAMK2_CAMK2A_ST	Q4G163	FBXO43	Q9UQM7	CAMK2A	T234	D236G	236	Missense	proximal	2	no	6.441	4.606	PhosphoSitePlus	COSMIC	4.810	Loss
CAMK_CAMK2_CAMK2A_ST	Q4G163	FBXO43	Q9UQM7	CAMK2A	S385	E389K	389	Missense	distal	4	no	6.448	6.272	EPSD	COSMIC	4.810	Down-regulation
CAMK_CAMK2_CAMK2A_ST	Q4G163	FBXO43	Q9UQM7	CAMK2A	S385	S391I	391	Missense	distal	6	no	6.448	6.357	EPSD	COSMIC	4.810	Down-regulation
CAMK_CAMK2_CAMK2A_ST	Q4G163	FBXO43	Q9UQM7	CAMK2A	S385	L378P	378	Missense	distal	-7	no	6.448	6.482	EPSD	COSMIC	4.810	Up-regulation
CAMK_CAMK2_CAMK2A_ST	Q4G163	FBXO43	Q9UQM7	CAMK2A	S385	G379E	379	Missense	distal	-6	no	6.448	6.238	EPSD	COSMIC	4.810	Down-regulation
CAMK_CAMK2_CAMK2A_ST	Q4G163	FBXO43	Q9UQM7	CAMK2A	S385	S381L	381	Missense	distal	-4	no	6.448	6.150	EPSD	COSMIC;CCLE	4.810	Down-regulation
CAMK_CAMK2_CAMK2A_ST	Q4G163	FBXO43	Q9UQM7	CAMK2A	S698	N704K	704	Missense	distal	6	no	4.896	4.866	EPSD	COSMIC	4.810	Down-regulation
CAMK_CAMK2_CAMK2A_ST	P55042	RRAD	Q9UQM7	CAMK2A	S214	R209H	209	Missense	distal	-5	no	11.533	11.479	EPSD	COSMIC;GDSC;CCLE	4.810	Down-regulation
CAMK_CAMK2_CAMK2A_ST	P55042	RRAD	Q9UQM7	CAMK2A	S257	D256Y	256	Missense	proximal	-1	no	7.537	7.580	EPSD	COSMIC	4.810	Up-regulation
CAMK_CAMK2_CAMK2A_ST	P55042	RRAD	Q9UQM7	CAMK2A	S273	A278E	278	Missense	distal	5	no	8.905	8.792	PhosphoSitePlus	COSMIC	4.810	Down-regulation
CAMK_CAMK2_CAMK2A_ST	P55042	RRAD	Q9UQM7	CAMK2A	S273	T268I	268	Missense	distal	-5	no	8.905	8.707	PhosphoSitePlus	COSMIC;GDSC;CCLE	4.810	Down-regulation
CAMK_CAMK2_CAMK2A_ST	P55042	RRAD	Q9UQM7	CAMK2A	S299	S306L	306	Missense	distal	7	no	8.617	8.780	EPSD	COSMIC	4.810	Up-regulation
CAMK_CAMK2_CAMK2A_ST	P55042	RRAD	Q9UQM7	CAMK2A	S299	D304Y	304	Missense	distal	5	no	8.617	8.551	EPSD	COSMIC	4.810	Down-regulation
CAMK_CAMK2_CAMK2A_ST	P55042	RRAD	Q9UQM7	CAMK2A	S299	S299F	299	Missense	central	0	yes	8.617	0.000	EPSD	COSMIC	4.810	Loss
CAMK_CAMK2_CAMK2A_ST	P55042	RRAD	Q9UQM7	CAMK2A	S301	S306L	306	Missense	distal	5	no	6.107	5.818	EPSD	COSMIC	4.810	Down-regulation
CAMK_CAMK2_CAMK2A_ST	P55042	RRAD	Q9UQM7	CAMK2A	S301	D304Y	304	Missense	distal	3	no	6.107	5.755	EPSD	COSMIC	4.810	Down-regulation
CAMK_CAMK2_CAMK2A_ST	P55042	RRAD	Q9UQM7	CAMK2A	S301	S299F	299	Missense	proximal	-2	no	6.107	5.322	EPSD	COSMIC	4.810	Down-regulation
CAMK_CAMK2_CAMK2A_ST	P16949	STMN1	Q9UQM7	CAMK2A	S16	R14C	14	Missense	proximal	-2	no	6.341	5.538	PhosphoSitePlus	COSMIC	4.810	Down-regulation
CAMK_CAMK2_CAMK2A_ST	P16949	STMN1	Q9UQM7	CAMK2A	S16	Q18E	18	Missense	proximal	2	no	6.341	7.471	PhosphoSitePlus	COSMIC	4.810	Up-regulation
CAMK_CAMK2_CAMK2A_ST	P16949	STMN1	Q9UQM7	CAMK2A	S46	D44N	44	Missense	proximal	-2	no	4.633	5.065	EPSD	COSMIC	4.810	Gain
CAMK_CAMK2_CAMK2A_ST	P16949	STMN1	Q9UQM7	CAMK2A	S63	R61S	61	Missense	proximal	-2	no	9.684	9.613	EPSD	COSMIC	4.810	Down-regulation
CAMK_CAMK2_CAMK2A_ST	P16949	STMN1	Q9UQM7	CAMK2A	S139	E132K	132	Missense	distal	-7	no	6.940	6.831	EPSD	COSMIC	4.810	Down-regulation
CAMK_CAMK2_CAMK2A_ST	P16949	STMN1	Q9UQM7	CAMK2A	S139	E145K	145	Missense	distal	6	no	6.940	6.889	EPSD	COSMIC	4.810	Down-regulation
CAMK_CAMK2_CAMK2A_ST	P35372	OPRM1	Q9UQM7	CAMK2A	S263	R265L	265	Missense	proximal	2	no	6.592	5.855	EPSD	COSMIC	4.810	Down-regulation
CAMK_CAMK2_CAMK2A_ST	P35372	OPRM1	Q9UQM7	CAMK2A	S263	L259V	259	Missense	distal	-4	no	6.592	6.609	EPSD	COSMIC	4.810	Up-regulation
CAMK_CAMK2_CAMK2A_ST	P35372	OPRM1	Q9UQM7	CAMK2A	S263	R260S	260	Missense	distal	-3	no	6.592	2.132	EPSD	COSMIC	4.810	Loss
CAMK_CAMK2_CAMK2A_ST	P35372	OPRM1	Q9UQM7	CAMK2A	S263	S270F	270	Missense	distal	7	no	6.592	6.838	EPSD	COSMIC	4.810	Up-regulation
CAMK_CAMK2_CAMK2A_ST	P35372	OPRM1	Q9UQM7	CAMK2A	S263	K262R	262	Missense	proximal	-1	no	6.592	6.441	EPSD	COSMIC	4.810	Down-regulation
CAMK_CAMK2_CAMK2A_ST	P35372	OPRM1	Q9UQM7	CAMK2A	S263	L256I	256	Missense	distal	-7	no	6.592	6.671	EPSD	COSMIC	4.810	Up-regulation
CAMK_CAMK2_CAMK2A_ST	P35372	OPRM1	Q9UQM7	CAMK2A	S268	D274G	274	Missense	distal	6	no	6.827	6.738	PhosphoSitePlus	COSMIC	4.810	Down-regulation
CAMK_CAMK2_CAMK2A_ST	P35372	OPRM1	Q9UQM7	CAMK2A	S268	R265L	265	Missense	distal	-3	no	6.827	1.705	PhosphoSitePlus	COSMIC	4.810	Loss
CAMK_CAMK2_CAMK2A_ST	P35372	OPRM1	Q9UQM7	CAMK2A	S268	K271N	271	Missense	distal	3	no	6.827	6.742	PhosphoSitePlus	COSMIC	4.810	Down-regulation
CAMK_CAMK2_CAMK2A_ST	P35372	OPRM1	Q9UQM7	CAMK2A	S268	S270F	270	Missense	proximal	2	no	6.827	5.577	PhosphoSitePlus	COSMIC	4.810	Down-regulation
CAMK_CAMK2_CAMK2A_ST	P35372	OPRM1	Q9UQM7	CAMK2A	S268	K262R	262	Missense	distal	-6	no	6.827	6.799	PhosphoSitePlus	COSMIC	4.810	Down-regulation
CAMK_CAMK2_CAMK2A_ST	P35372	OPRM1	Q9UQM7	CAMK2A	S365	I360T	360	Missense	distal	-5	no	4.612	4.810	EPSD	COSMIC	4.810	Gain
CAMK_CAMK2_CAMK2A_ST	P35372	OPRM1	Q9UQM7	CAMK2A	T372	A379S	379	Missense	distal	7	no	9.812	9.767	EPSD	COSMIC	4.810	Down-regulation
CAMK_CAMK2_CAMK2A_ST	P35372	OPRM1	Q9UQM7	CAMK2A	T372	P376H	376	Missense	distal	4	no	9.812	9.925	EPSD	COSMIC	4.810	Up-regulation
CAMK_CAMK2_CAMK2A_ST	Q9Y496	KIF3A	Q9UQM7	CAMK2A	S38	E41Q	41	Missense	distal	3	no	7.387	7.179	EPSD	COSMIC	4.810	Down-regulation
CAMK_CAMK2_CAMK2A_ST	Q9Y496	KIF3A	Q9UQM7	CAMK2A	S38	E41K	41	Missense	distal	3	no	7.387	7.222	EPSD	COSMIC	4.810	Down-regulation
CAMK_CAMK2_CAMK2A_ST	Q9Y496	KIF3A	Q9UQM7	CAMK2A	S415	D417N	417	Missense	proximal	2	no	6.907	5.896	EPSD	COSMIC	4.810	Down-regulation
CAMK_CAMK2_CAMK2A_ST	Q9Y496	KIF3A	Q9UQM7	CAMK2A	S415	R408K	408	Missense	distal	-7	no	6.907	6.841	EPSD	COSMIC	4.810	Down-regulation
CAMK_CAMK2_CAMK2A_ST	Q9Y496	KIF3A	Q9UQM7	CAMK2A	T633	G626E	626	Missense	distal	-7	no	6.443	6.154	EPSD	COSMIC	4.810	Down-regulation
CAMK_CAMK2_CAMK2A_ST	Q9Y496	KIF3A	Q9UQM7	CAMK2A	T672	K666R	666	Missense	distal	-6	no	7.746	7.718	EPSD	COSMIC	4.810	Down-regulation
CAMK_CAMK2_CAMK2A_ST	Q9Y496	KIF3A	Q9UQM7	CAMK2A	T672	E668K	668	Missense	distal	-4	no	7.746	7.698	EPSD	COSMIC	4.810	Down-regulation
CAMK_CAMK2_CAMK2A_ST	Q9Y4D2	DAGLA	Q9UQM7	CAMK2A	S732	E738K	738	Missense	distal	6	no	5.124	5.073	EPSD	COSMIC	4.810	Down-regulation
CAMK_CAMK2_CAMK2A_ST	Q9Y4D2	DAGLA	Q9UQM7	CAMK2A	S743	R740P	740	Missense	distal	-3	no	5.894	0.976	EPSD	COSMIC	4.810	Loss
CAMK_CAMK2_CAMK2A_ST	Q9Y4D2	DAGLA	Q9UQM7	CAMK2A	S743	A747V	747	Missense	distal	4	no	5.894	5.839	EPSD	COSMIC;GDSC	4.810	Down-regulation
CAMK_CAMK2_CAMK2A_ST	Q9Y4D2	DAGLA	Q9UQM7	CAMK2A	S743	E738K	738	Missense	distal	-5	no	5.894	5.891	EPSD	COSMIC	4.810	Down-regulation
CAMK_CAMK2_CAMK2A_ST	Q9Y4D2	DAGLA	Q9UQM7	CAMK2A	S798	R801C	801	Missense	distal	3	no	6.335	6.072	EPSD	COSMIC	4.810	Down-regulation
CAMK_CAMK2_CAMK2A_ST	Q9Y4D2	DAGLA	Q9UQM7	CAMK2A	S798	R796C	796	Missense	proximal	-2	no	6.335	5.532	EPSD	COSMIC	4.810	Down-regulation
CAMK_CAMK2_CAMK2A_ST	Q9Y4D2	DAGLA	Q9UQM7	CAMK2A	S798	R796H	796	Missense	proximal	-2	no	6.335	6.215	EPSD	COSMIC;GDSC;CCLE	4.810	Down-regulation
CAMK_CAMK2_CAMK2A_ST	Q9Y4D2	DAGLA	Q9UQM7	CAMK2A	S798	S797F	797	Missense	proximal	-1	no	6.335	5.994	EPSD	COSMIC	4.810	Down-regulation
CAMK_CAMK2_CAMK2A_ST	Q9Y4D2	DAGLA	Q9UQM7	CAMK2A	S850	A843T	843	Missense	distal	-7	no	5.879	6.220	EPSD	COSMIC	4.810	Up-regulation
CAMK_CAMK2_CAMK2A_ST	Q9Y4D2	DAGLA	Q9UQM7	CAMK2A	S872	A873V	873	Missense	proximal	1	no	7.599	7.951	EPSD	COSMIC	4.810	Up-regulation
CAMK_CAMK2_CAMK2A_ST	Q9Y4D2	DAGLA	Q9UQM7	CAMK2A	S872	A874V	874	Missense	proximal	2	no	7.599	7.585	EPSD	COSMIC	4.810	Down-regulation
CAMK_CAMK2_CAMK2A_ST	Q9Y4D2	DAGLA	Q9UQM7	CAMK2A	S954	G949S	949	Missense	distal	-5	no	4.938	4.903	EPSD	COSMIC	4.810	Down-regulation
CAMK_CAMK2_CAMK2A_ST	Q9Y4D2	DAGLA	Q9UQM7	CAMK2A	S954	Q955H	955	Missense	proximal	1	no	4.938	5.478	EPSD	COSMIC	4.810	Up-regulation
CAMK_CAMK2_CAMK2A_ST	Q9Y4D2	DAGLA	Q9UQM7	CAMK2A	S954	A947T	947	Missense	distal	-7	no	4.938	5.279	EPSD	COSMIC;GDSC;CCLE	4.810	Up-regulation
CAMK_CAMK2_CAMK2A_ST	Q9Y4D2	DAGLA	Q9UQM7	CAMK2A	S954	G949D	949	Missense	distal	-5	no	4.938	4.954	EPSD	COSMIC	4.810	Up-regulation
CAMK_CAMK2_CAMK2A_ST	Q9Y4D2	DAGLA	Q9UQM7	CAMK2A	T1023	P1024L	1024	Missense	proximal	1	no	4.713	5.371	EPSD	COSMIC	4.810	Gain
CAMK_CAMK2_CAMK2A_ST	Q9BXL7	CARD11	Q9UQM7	CAMK2A	S116	T112I	112	Missense	distal	-4	no	7.539	7.442	PhosphoSitePlus	COSMIC	4.810	Down-regulation
CAMK_CAMK2_CAMK2A_ST	Q9BXL7	CARD11	Q9UQM7	CAMK2A	S116	G123D	123	Missense	distal	7	no	7.539	7.509	PhosphoSitePlus	COSMIC	4.810	Down-regulation
CAMK_CAMK2_CAMK2A_ST	Q9BXL7	CARD11	Q9UQM7	CAMK2A	S116	S116P	116	Missense	central	0	yes	7.539	0.000	PhosphoSitePlus	COSMIC	4.810	Loss
CAMK_CAMK2_CAMK2A_ST	Q9BXL7	CARD11	Q9UQM7	CAMK2A	S116	F115L	115	Missense	proximal	-1	no	7.539	7.670	PhosphoSitePlus	COSMIC	4.810	Up-regulation
CAMK_CAMK2_CAMK2A_ST	Q9BXL7	CARD11	Q9UQM7	CAMK2A	S116	T117A	117	Missense	proximal	1	no	7.539	7.440	PhosphoSitePlus	COSMIC	4.810	Down-regulation
CAMK_CAMK2_CAMK2A_ST	Q9BXL7	CARD11	Q9UQM7	CAMK2A	S116	R113Q	113	Missense	distal	-3	no	7.539	3.967	PhosphoSitePlus	COSMIC	4.810	Loss
CAMK_CAMK2_CAMK2A_ST	Q9BXL7	CARD11	Q9UQM7	CAMK2A	S116	F115S	115	Missense	proximal	-1	no	7.539	7.880	PhosphoSitePlus	COSMIC	4.810	Up-regulation
CAMK_CAMK2_CAMK2A_ST	Q9BXL7	CARD11	Q9UQM7	CAMK2A	S116	R114K	114	Missense	proximal	-2	no	7.539	7.715	PhosphoSitePlus	COSMIC;GDSC;CCLE	4.810	Up-regulation
CAMK_CAMK2_CAMK2A_ST	Q9BXL7	CARD11	Q9UQM7	CAMK2A	S116	G123C	123	Missense	distal	7	no	7.539	7.704	PhosphoSitePlus	COSMIC	4.810	Up-regulation
CAMK_CAMK2_CAMK2A_ST	Q9BXL7	CARD11	Q9UQM7	CAMK2A	T117	T112I	112	Missense	distal	-5	no	6.080	5.881	EPSD	COSMIC	4.810	Down-regulation
CAMK_CAMK2_CAMK2A_ST	Q9BXL7	CARD11	Q9UQM7	CAMK2A	T117	G123D	123	Missense	distal	6	no	6.080	6.169	EPSD	COSMIC	4.810	Up-regulation
CAMK_CAMK2_CAMK2A_ST	Q9BXL7	CARD11	Q9UQM7	CAMK2A	T117	S116P	116	Missense	proximal	-1	no	6.080	5.894	EPSD	COSMIC	4.810	Down-regulation
CAMK_CAMK2_CAMK2A_ST	Q9BXL7	CARD11	Q9UQM7	CAMK2A	T117	F115L	115	Missense	proximal	-2	no	6.080	6.762	EPSD	COSMIC	4.810	Up-regulation
CAMK_CAMK2_CAMK2A_ST	Q9BXL7	CARD11	Q9UQM7	CAMK2A	T117	T117A	117	Missense	central	0	yes	6.080	0.000	EPSD	COSMIC	4.810	Loss
CAMK_CAMK2_CAMK2A_ST	Q9BXL7	CARD11	Q9UQM7	CAMK2A	T117	R113Q	113	Missense	distal	-4	no	6.080	5.974	EPSD	COSMIC	4.810	Down-regulation
CAMK_CAMK2_CAMK2A_ST	Q9BXL7	CARD11	Q9UQM7	CAMK2A	T117	F115S	115	Missense	proximal	-2	no	6.080	6.865	EPSD	COSMIC	4.810	Up-regulation
CAMK_CAMK2_CAMK2A_ST	Q9BXL7	CARD11	Q9UQM7	CAMK2A	T117	R114K	114	Missense	distal	-3	no	6.080	3.812	EPSD	COSMIC;GDSC;CCLE	4.810	Loss
CAMK_CAMK2_CAMK2A_ST	Q9BXL7	CARD11	Q9UQM7	CAMK2A	T117	G123C	123	Missense	distal	6	no	6.080	5.976	EPSD	COSMIC	4.810	Down-regulation
CAMK_CAMK2_CAMK2A_ST	Q9BXL7	CARD11	Q9UQM7	CAMK2A	S439	E432K	432	Missense	distal	-7	no	8.768	8.660	EPSD	COSMIC	4.810	Down-regulation
CAMK_CAMK2_CAMK2A_ST	Q9BXL7	CARD11	Q9UQM7	CAMK2A	S439	D441N	441	Missense	proximal	2	no	8.768	7.758	EPSD	COSMIC	4.810	Down-regulation
CAMK_CAMK2_CAMK2A_ST	Q9BXL7	CARD11	Q9UQM7	CAMK2A	S439	N444K	444	Missense	distal	5	no	8.768	8.848	EPSD	COSMIC	4.810	Up-regulation
CAMK_CAMK2_CAMK2A_ST	Q9BXL7	CARD11	Q9UQM7	CAMK2A	S439	R436W	436	Missense	distal	-3	no	8.768	-3.252	EPSD	COSMIC	4.810	Loss
CAMK_CAMK2_CAMK2A_ST	Q9BXL7	CARD11	Q9UQM7	CAMK2A	S439	R437C	437	Missense	proximal	-2	no	8.768	7.966	EPSD	COSMIC	4.810	Down-regulation
CAMK_CAMK2_CAMK2A_ST	Q9BXL7	CARD11	Q9UQM7	CAMK2A	S439	R436Q	436	Missense	distal	-3	no	8.768	5.197	EPSD	COSMIC;GDSC;CCLE	4.810	Down-regulation
CAMK_CAMK2_CAMK2A_ST	Q9BXL7	CARD11	Q9UQM7	CAMK2A	S439	S439F	439	Missense	central	0	yes	8.768	0.000	EPSD	COSMIC	4.810	Loss
CAMK_CAMK2_CAMK2A_ST	Q9BXL7	CARD11	Q9UQM7	CAMK2A	S512	R509I	509	Missense	distal	-3	no	6.859	2.587	EPSD	COSMIC	4.810	Loss
CAMK_CAMK2_CAMK2A_ST	Q9BXL7	CARD11	Q9UQM7	CAMK2A	S512	P513F	513	Missense	proximal	1	no	6.859	7.411	EPSD	COSMIC	4.810	Up-regulation
CAMK_CAMK2_CAMK2A_ST	Q9BXL7	CARD11	Q9UQM7	CAMK2A	S512	P513S	513	Missense	proximal	1	no	6.859	7.226	EPSD	COSMIC	4.810	Up-regulation
CAMK_CAMK2_CAMK2A_ST	Q9BXL7	CARD11	Q9UQM7	CAMK2A	S512	S512F	512	Missense	central	0	yes	6.859	0.000	EPSD	COSMIC	4.810	Loss
CAMK_CAMK2_CAMK2A_ST	Q9BXL7	CARD11	Q9UQM7	CAMK2A	S512	P513L	513	Missense	proximal	1	no	6.859	7.517	EPSD	COSMIC	4.810	Up-regulation
CAMK_CAMK2_CAMK2A_ST	Q9BXL7	CARD11	Q9UQM7	CAMK2A	S512	P513H	513	Missense	proximal	1	no	6.859	7.552	EPSD	COSMIC	4.810	Up-regulation
CAMK_CAMK2_CAMK2A_ST	Q9BXL7	CARD11	Q9UQM7	CAMK2A	S512	A510V	510	Missense	proximal	-2	no	6.859	6.441	EPSD	COSMIC;GDSC;CCLE	4.810	Down-regulation
CAMK_CAMK2_CAMK2A_ST	Q9BXL7	CARD11	Q9UQM7	CAMK2A	S520	P513F	513	Missense	distal	-7	no	5.861	6.293	EPSD	COSMIC	4.810	Up-regulation
CAMK_CAMK2_CAMK2A_ST	Q9BXL7	CARD11	Q9UQM7	CAMK2A	S520	A524S	524	Missense	distal	4	no	5.861	5.914	EPSD	COSMIC	4.810	Up-regulation
CAMK_CAMK2_CAMK2A_ST	Q9BXL7	CARD11	Q9UQM7	CAMK2A	S520	P513S	513	Missense	distal	-7	no	5.861	5.732	EPSD	COSMIC	4.810	Down-regulation
CAMK_CAMK2_CAMK2A_ST	Q9BXL7	CARD11	Q9UQM7	CAMK2A	S520	H527N	527	Missense	distal	7	no	5.861	5.851	EPSD	COSMIC;GDSC;CCLE	4.810	Down-regulation
CAMK_CAMK2_CAMK2A_ST	Q9BXL7	CARD11	Q9UQM7	CAMK2A	S520	P513L	513	Missense	distal	-7	no	5.861	5.826	EPSD	COSMIC	4.810	Down-regulation
CAMK_CAMK2_CAMK2A_ST	Q9BXL7	CARD11	Q9UQM7	CAMK2A	S520	K525R	525	Missense	distal	5	no	5.861	5.752	EPSD	COSMIC	4.810	Down-regulation
CAMK_CAMK2_CAMK2A_ST	Q9BXL7	CARD11	Q9UQM7	CAMK2A	S520	P513H	513	Missense	distal	-7	no	5.861	5.640	EPSD	COSMIC	4.810	Down-regulation
CAMK_CAMK2_CAMK2A_ST	Q9BXL7	CARD11	Q9UQM7	CAMK2A	S520	A524T	524	Missense	distal	4	no	5.861	5.822	EPSD	COSMIC	4.810	Down-regulation
CAMK_CAMK2_CAMK2A_ST	Q9BXL7	CARD11	Q9UQM7	CAMK2A	S520	H527R	527	Missense	distal	7	no	5.861	5.909	EPSD	COSMIC	4.810	Up-regulation
CAMK_CAMK2_CAMK2A_ST	Q9BXL7	CARD11	Q9UQM7	CAMK2A	S558	R557S	557	Missense	proximal	-1	no	6.946	7.034	EPSD	COSMIC	4.810	Up-regulation
CAMK_CAMK2_CAMK2A_ST	Q9BXL7	CARD11	Q9UQM7	CAMK2A	S558	P554S	554	Missense	distal	-4	no	6.946	7.324	EPSD	COSMIC	4.810	Up-regulation
CAMK_CAMK2_CAMK2A_ST	Q9BXL7	CARD11	Q9UQM7	CAMK2A	S558	A565V	565	Missense	distal	7	no	6.946	6.976	EPSD	COSMIC	4.810	Up-regulation
CAMK_CAMK2_CAMK2A_ST	Q9BXL7	CARD11	Q9UQM7	CAMK2A	S558	P553T	553	Missense	distal	-5	no	6.946	6.942	EPSD	COSMIC	4.810	Down-regulation
CAMK_CAMK2_CAMK2A_ST	Q9BXL7	CARD11	Q9UQM7	CAMK2A	S558	A565T	565	Missense	distal	7	no	6.946	6.995	EPSD	COSMIC	4.810	Up-regulation
CAMK_CAMK2_CAMK2A_ST	Q9BXL7	CARD11	Q9UQM7	CAMK2A	S558	S559C	559	Missense	proximal	1	no	6.946	6.728	EPSD	COSMIC	4.810	Down-regulation
CAMK_CAMK2_CAMK2A_ST	Q9BXL7	CARD11	Q9UQM7	CAMK2A	S618	S618C	618	Missense	central	0	yes	5.235	0.000	EPSD	COSMIC	4.810	Loss
CAMK_CAMK2_CAMK2A_ST	Q9BXL7	CARD11	Q9UQM7	CAMK2A	S618	S618F	618	Missense	central	0	yes	5.235	0.000	EPSD	COSMIC	4.810	Loss
CAMK_CAMK2_CAMK2A_ST	Q9BXL7	CARD11	Q9UQM7	CAMK2A	S618	S615F	615	Missense	distal	-3	no	5.235	-3.852	EPSD	COSMIC	4.810	Loss
CAMK_CAMK2_CAMK2A_ST	Q9BXL7	CARD11	Q9UQM7	CAMK2A	S618	S622H	622	Missense	distal	4	no	5.235	5.175	EPSD	COSMIC	4.810	Down-regulation
CAMK_CAMK2_CAMK2A_ST	Q9BXL7	CARD11	Q9UQM7	CAMK2A	S618	S622F	622	Missense	distal	4	no	5.235	5.077	EPSD	COSMIC	4.810	Down-regulation
CAMK_CAMK2_CAMK2A_ST	Q9BXL7	CARD11	Q9UQM7	CAMK2A	S618	P613L	613	Missense	distal	-5	no	5.235	5.142	EPSD	COSMIC	4.810	Down-regulation
CAMK_CAMK2_CAMK2A_ST	Q9BXL7	CARD11	Q9UQM7	CAMK2A	S618	S622C	622	Missense	distal	4	no	5.235	4.871	EPSD	COSMIC	4.810	Down-regulation
CAMK_CAMK2_CAMK2A_ST	Q9BXL7	CARD11	Q9UQM7	CAMK2A	S618	S625C	625	Missense	distal	7	no	5.235	5.495	EPSD	COSMIC	4.810	Up-regulation
CAMK_CAMK2_CAMK2A_ST	Q9BXL7	CARD11	Q9UQM7	CAMK2A	S618	S618A	618	Missense	central	0	yes	5.235	0.000	EPSD	COSMIC;CCLE	4.810	Loss
CAMK_CAMK2_CAMK2A_ST	Q9BXL7	CARD11	Q9UQM7	CAMK2A	S618	S619F	619	Missense	proximal	1	no	5.235	5.420	EPSD	COSMIC	4.810	Up-regulation
CAMK_CAMK2_CAMK2A_ST	Q9BXL7	CARD11	Q9UQM7	CAMK2A	S618	H617Y	617	Missense	proximal	-1	no	5.235	5.041	EPSD	COSMIC	4.810	Down-regulation
CAMK_CAMK2_CAMK2A_ST	Q9BXL7	CARD11	Q9UQM7	CAMK2A	S618	S615P	615	Missense	distal	-3	no	5.235	4.778	EPSD	COSMIC	4.810	Loss
CAMK_CAMK2_CAMK2A_ST	Q9BXL7	CARD11	Q9UQM7	CAMK2A	S644	L645P	645	Missense	proximal	1	no	8.796	8.137	EPSD	COSMIC	4.810	Down-regulation
CAMK_CAMK2_CAMK2A_ST	Q9BXL7	CARD11	Q9UQM7	CAMK2A	S644	L645Q	645	Missense	proximal	1	no	8.796	8.290	EPSD	COSMIC	4.810	Down-regulation
CAMK_CAMK2_CAMK2A_ST	Q9BXL7	CARD11	Q9UQM7	CAMK2A	S644	F649S	649	Missense	distal	5	no	8.796	9.056	EPSD	COSMIC	4.810	Up-regulation
CAMK_CAMK2_CAMK2A_ST	Q9BXL7	CARD11	Q9UQM7	CAMK2A	S644	M639V	639	Missense	distal	-5	no	8.796	8.767	EPSD	COSMIC	4.810	Down-regulation
CAMK_CAMK2_CAMK2A_ST	Q9BXL7	CARD11	Q9UQM7	CAMK2A	S644	R647S	647	Missense	distal	3	no	8.796	8.890	EPSD	COSMIC	4.810	Up-regulation
CAMK_CAMK2_CAMK2A_ST	Q9BXL7	CARD11	Q9UQM7	CAMK2A	S923	P926S	926	Missense	distal	3	no	6.853	7.125	EPSD	COSMIC	4.810	Up-regulation
CAMK_CAMK2_CAMK2A_ST	Q9BXL7	CARD11	Q9UQM7	CAMK2A	S923	S929R	929	Missense	distal	6	no	6.853	6.855	EPSD	COSMIC	4.810	Up-regulation
CAMK_CAMK2_CAMK2A_ST	Q9BXL7	CARD11	Q9UQM7	CAMK2A	S923	R920C	920	Missense	distal	-3	no	6.853	1.273	EPSD	COSMIC	4.810	Loss
CAMK_CAMK2_CAMK2A_ST	Q9BXL7	CARD11	Q9UQM7	CAMK2A	S923	S925N	925	Missense	proximal	2	no	6.853	7.683	EPSD	COSMIC	4.810	Up-regulation
CAMK_CAMK2_CAMK2A_ST	Q9BXL7	CARD11	Q9UQM7	CAMK2A	S923	R918Q	918	Missense	distal	-5	no	6.853	6.756	EPSD	COSMIC	4.810	Down-regulation
CAMK_CAMK2_CAMK2A_ST	Q9BXL7	CARD11	Q9UQM7	CAMK2A	T1020	Q1018H	1018	Missense	proximal	-2	no	6.645	6.307	EPSD	COSMIC	4.810	Down-regulation
CAMK_CAMK2_CAMK2A_ST	Q9BXL7	CARD11	Q9UQM7	CAMK2A	T1020	E1021K	1021	Missense	proximal	1	no	6.645	6.390	EPSD	COSMIC	4.810	Down-regulation
CAMK_CAMK2_CAMK2A_ST	Q9BXL7	CARD11	Q9UQM7	CAMK2A	T1020	R1016K	1016	Missense	distal	-4	no	6.645	6.654	EPSD	COSMIC	4.810	Up-regulation
CAMK_CAMK2_CAMK2A_ST	Q9BXL7	CARD11	Q9UQM7	CAMK2A	T1020	R1017K	1017	Missense	distal	-3	no	6.645	4.377	EPSD	COSMIC	4.810	Loss
CAMK_CAMK2_CAMK2A_ST	Q9BXL7	CARD11	Q9UQM7	CAMK2A	T1020	I1024T	1024	Missense	distal	4	no	6.645	6.817	EPSD	COSMIC	4.810	Up-regulation
CAMK_CAMK2_CAMK2A_ST	Q9BXL7	CARD11	Q9UQM7	CAMK2A	T1020	L1015F	1015	Missense	distal	-5	no	6.645	6.754	EPSD	COSMIC	4.810	Up-regulation
CAMK_CAMK2_CAMK2A_ST	Q9BXL7	CARD11	Q9UQM7	CAMK2A	T1020	E1013K	1013	Missense	distal	-7	no	6.645	6.536	EPSD	COSMIC	4.810	Down-regulation
CAMK_CAMK2_CAMK2A_ST	Q01970	PLCB3	Q9UQM7	CAMK2A	S26	E33K	33	Missense	distal	7	no	6.880	7.090	EPSD	COSMIC	4.810	Up-regulation
CAMK_CAMK2_CAMK2A_ST	Q01970	PLCB3	Q9UQM7	CAMK2A	S26	V19M	19	Missense	distal	-7	no	6.880	6.650	EPSD	COSMIC;CCLE	4.810	Down-regulation
CAMK_CAMK2_CAMK2A_ST	Q01970	PLCB3	Q9UQM7	CAMK2A	S148	L153R	153	Missense	distal	5	no	5.158	5.306	EPSD	COSMIC	4.810	Up-regulation
CAMK_CAMK2_CAMK2A_ST	Q01970	PLCB3	Q9UQM7	CAMK2A	S148	R154H	154	Missense	distal	6	no	5.158	5.132	EPSD	COSMIC;GDSC;CCLE	4.810	Down-regulation
CAMK_CAMK2_CAMK2A_ST	Q01970	PLCB3	Q9UQM7	CAMK2A	S480	A481V	481	Missense	proximal	1	no	4.514	4.866	EPSD	COSMIC	4.810	Gain
CAMK_CAMK2_CAMK2A_ST	Q01970	PLCB3	Q9UQM7	CAMK2A	S497	S490N	490	Missense	distal	-7	no	4.833	4.930	EPSD	COSMIC	4.810	Up-regulation
CAMK_CAMK2_CAMK2A_ST	Q01970	PLCB3	Q9UQM7	CAMK2A	S497	E502K	502	Missense	distal	5	no	4.833	4.863	EPSD	COSMIC	4.810	Up-regulation
CAMK_CAMK2_CAMK2A_ST	Q01970	PLCB3	Q9UQM7	CAMK2A	S512	S515I	515	Missense	distal	3	no	5.940	5.695	EPSD	COSMIC	4.810	Down-regulation
CAMK_CAMK2_CAMK2A_ST	Q01970	PLCB3	Q9UQM7	CAMK2A	S512	P517S	517	Missense	distal	5	no	5.940	6.170	EPSD	COSMIC	4.810	Up-regulation
CAMK_CAMK2_CAMK2A_ST	Q01970	PLCB3	Q9UQM7	CAMK2A	S814	H821R	821	Missense	distal	7	no	4.771	4.819	EPSD	COSMIC	4.810	Gain
CAMK_CAMK2_CAMK2A_ST	Q01970	PLCB3	Q9UQM7	CAMK2A	S867	I860T	860	Missense	distal	-7	no	4.864	4.793	EPSD	COSMIC	4.810	Loss
CAMK_CAMK2_CAMK2A_ST	Q01970	PLCB3	Q9UQM7	CAMK2A	S1216	A1213T	1213	Missense	distal	-3	no	5.634	4.997	EPSD	COSMIC	4.810	Down-regulation
CAMK_CAMK2_CAMK2A_ST	P16070	CD44	Q9UQM7	CAMK2A	S182	G181S	181	Missense	proximal	-1	no	4.750	4.896	EPSD	COSMIC;GDSC;CCLE	4.810	Gain
CAMK_CAMK2_CAMK2A_ST	P16070	CD44	Q9UQM7	CAMK2A	S184	G181S	181	Missense	distal	-3	no	4.795	4.933	EPSD	COSMIC;GDSC;CCLE	4.810	Gain
CAMK_CAMK2_CAMK2A_ST	P16070	CD44	Q9UQM7	CAMK2A	S291	S295P	295	Missense	distal	4	no	8.268	8.095	EPSD	COSMIC;CCLE	4.810	Down-regulation
CAMK_CAMK2_CAMK2A_ST	P16070	CD44	Q9UQM7	CAMK2A	S717	Q723P	723	Missense	distal	6	no	6.559	6.468	EPSD	COSMIC	4.810	Down-regulation
CAMK_CAMK2_CAMK2A_ST	P16070	CD44	Q9UQM7	CAMK2A	S717	P721Q	721	Missense	distal	4	no	6.559	6.730	EPSD	COSMIC	4.810	Up-regulation
CAMK_CAMK2_CAMK2A_ST	P16070	CD44	Q9UQM7	CAMK2A	S717	K715N	715	Missense	proximal	-2	no	6.559	6.461	EPSD	COSMIC	4.810	Down-regulation
CAMK_CAMK2_CAMK2A_ST	P16070	CD44	Q9UQM7	CAMK2A	S718	Q723P	723	Missense	distal	5	no	5.165	5.078	EPSD	COSMIC	4.810	Down-regulation
CAMK_CAMK2_CAMK2A_ST	P16070	CD44	Q9UQM7	CAMK2A	S718	P721Q	721	Missense	distal	3	no	5.165	5.365	EPSD	COSMIC	4.810	Up-regulation
CAMK_CAMK2_CAMK2A_ST	P16070	CD44	Q9UQM7	CAMK2A	S718	K715N	715	Missense	distal	-3	no	5.165	2.599	EPSD	COSMIC	4.810	Loss
CAMK_CAMK2_CAMK2A_ST	Q14674	ESPL1	Q9UQM7	CAMK2A	S1433	R1429M	1429	Missense	distal	-4	no	5.412	5.255	EPSD	COSMIC	4.810	Down-regulation
CAMK_CAMK2_CAMK2A_ST	Q14674	ESPL1	Q9UQM7	CAMK2A	S1433	V1439M	1439	Missense	distal	6	no	5.412	5.496	EPSD	COSMIC	4.810	Up-regulation
CAMK_CAMK2_CAMK2A_ST	Q14674	ESPL1	Q9UQM7	CAMK2A	S1433	A1428T	1428	Missense	distal	-5	no	5.412	5.403	EPSD	COSMIC	4.810	Down-regulation
CAMK_CAMK2_CAMK2A_ST	Q14674	ESPL1	Q9UQM7	CAMK2A	S1455	G1450A	1450	Missense	distal	-5	no	5.460	5.431	EPSD	COSMIC	4.810	Down-regulation
CAMK_CAMK2_CAMK2A_ST	Q14674	ESPL1	Q9UQM7	CAMK2A	S1501	T1494S	1494	Missense	distal	-7	no	9.499	9.396	PhosphoSitePlus	COSMIC	4.810	Down-regulation
CAMK_CAMK2_CAMK2A_ST	Q14674	ESPL1	Q9UQM7	CAMK2A	S1538	K1540E	1540	Missense	proximal	2	no	5.686	7.727	EPSD	COSMIC	4.810	Up-regulation
CAMK_CAMK2_CAMK2A_ST	Q14674	ESPL1	Q9UQM7	CAMK2A	S1641	G1648R	1648	Missense	distal	7	no	8.168	8.178	EPSD	COSMIC	4.810	Up-regulation
CAMK_CAMK2_CAMK2A_ST	Q14674	ESPL1	Q9UQM7	CAMK2A	S1641	K1642N	1642	Missense	proximal	1	no	8.168	7.795	EPSD	COSMIC	4.810	Down-regulation
CAMK_CAMK2_CAMK2A_ST	Q14674	ESPL1	Q9UQM7	CAMK2A	S1820	G1814S	1814	Missense	distal	-6	no	5.228	5.135	EPSD	COSMIC;CCLE	4.810	Down-regulation
CAMK_CAMK2_CAMK2A_ST	O95180	CACNA1H	Q9UQM7	CAMK2A	S215	R212G	212	Missense	distal	-3	no	6.019	1.421	EPSD	COSMIC	4.810	Loss
CAMK_CAMK2_CAMK2A_ST	O95180	CACNA1H	Q9UQM7	CAMK2A	S215	R217W	217	Missense	proximal	2	no	6.019	4.423	EPSD	COSMIC	4.810	Loss
CAMK_CAMK2_CAMK2A_ST	O95180	CACNA1H	Q9UQM7	CAMK2A	S215	R208H	208	Missense	distal	-7	no	6.019	5.959	EPSD	COSMIC	4.810	Down-regulation
CAMK_CAMK2_CAMK2A_ST	O95180	CACNA1H	Q9UQM7	CAMK2A	S215	V220I	220	Missense	distal	5	no	6.019	5.916	EPSD	COSMIC	4.810	Down-regulation
CAMK_CAMK2_CAMK2A_ST	O95180	CACNA1H	Q9UQM7	CAMK2A	S475	R469H	469	Missense	distal	-6	no	5.128	5.082	EPSD	COSMIC	4.810	Down-regulation
CAMK_CAMK2_CAMK2A_ST	O95180	CACNA1H	Q9UQM7	CAMK2A	S475	K470N	470	Missense	distal	-5	no	5.128	5.307	EPSD	COSMIC	4.810	Up-regulation
CAMK_CAMK2_CAMK2A_ST	O95180	CACNA1H	Q9UQM7	CAMK2A	S475	R474H	474	Missense	proximal	-1	no	5.128	5.274	EPSD	COSMIC;GDSC;CCLE	4.810	Up-regulation
CAMK_CAMK2_CAMK2A_ST	O95180	CACNA1H	Q9UQM7	CAMK2A	S475	S475N	475	Missense	central	0	yes	5.128	0.000	EPSD	COSMIC;GDSC;CCLE	4.810	Loss
CAMK_CAMK2_CAMK2A_ST	O95180	CACNA1H	Q9UQM7	CAMK2A	S1107	G1106D	1106	Missense	proximal	-1	no	7.253	7.219	EPSD	COSMIC	4.810	Down-regulation
CAMK_CAMK2_CAMK2A_ST	O95180	CACNA1H	Q9UQM7	CAMK2A	S1107	D1112A	1112	Missense	distal	5	no	7.253	7.428	EPSD	COSMIC	4.810	Up-regulation
CAMK_CAMK2_CAMK2A_ST	O95180	CACNA1H	Q9UQM7	CAMK2A	S1108	G1106D	1106	Missense	proximal	-2	no	7.388	7.264	EPSD	COSMIC	4.810	Down-regulation
CAMK_CAMK2_CAMK2A_ST	O95180	CACNA1H	Q9UQM7	CAMK2A	S1108	D1112A	1112	Missense	distal	4	no	7.388	7.442	EPSD	COSMIC	4.810	Up-regulation
CAMK_CAMK2_CAMK2A_ST	O95180	CACNA1H	Q9UQM7	CAMK2A	S1110	G1106D	1106	Missense	distal	-4	no	5.115	5.167	EPSD	COSMIC	4.810	Up-regulation
CAMK_CAMK2_CAMK2A_ST	O95180	CACNA1H	Q9UQM7	CAMK2A	S1110	D1112A	1112	Missense	proximal	2	no	5.115	3.313	EPSD	COSMIC	4.810	Loss
CAMK_CAMK2_CAMK2A_ST	O95180	CACNA1H	Q9UQM7	CAMK2A	S1198	P1203L	1203	Missense	distal	5	no	9.663	9.604	PhosphoSitePlus	COSMIC	4.810	Down-regulation
CAMK_CAMK2_CAMK2A_ST	O95180	CACNA1H	Q9UQM7	CAMK2A	S1198	R1202Q	1202	Missense	distal	4	no	9.663	9.833	PhosphoSitePlus	COSMIC	4.810	Up-regulation
CAMK_CAMK2_CAMK2A_ST	O95180	CACNA1H	Q9UQM7	CAMK2A	S1198	R1205W	1205	Missense	distal	7	no	9.663	9.979	PhosphoSitePlus	COSMIC	4.810	Up-regulation
CAMK_CAMK2_CAMK2A_ST	O95180	CACNA1H	Q9UQM7	CAMK2A	S1198	R1202H	1202	Missense	distal	4	no	9.663	9.775	PhosphoSitePlus	COSMIC	4.810	Up-regulation
CAMK_CAMK2_CAMK2A_ST	O95180	CACNA1H	Q9UQM7	CAMK2A	S1587	R1584W	1584	Missense	distal	-3	no	5.655	-6.366	EPSD	COSMIC	4.810	Loss
CAMK_CAMK2_CAMK2A_ST	O95180	CACNA1H	Q9UQM7	CAMK2A	T1806	T1800M	1800	Missense	distal	-6	no	5.373	5.221	EPSD	COSMIC	4.810	Down-regulation
CAMK_CAMK2_CAMK2A_ST	O95180	CACNA1H	Q9UQM7	CAMK2A	T1806	R1803S	1803	Missense	distal	-3	no	5.373	0.912	EPSD	COSMIC	4.810	Loss
CAMK_CAMK2_CAMK2A_ST	O95180	CACNA1H	Q9UQM7	CAMK2A	T1806	T1800S	1800	Missense	distal	-6	no	5.373	5.302	EPSD	COSMIC	4.810	Down-regulation
CAMK_CAMK2_CAMK2A_ST	O95180	CACNA1H	Q9UQM7	CAMK2A	S1920	V1919M	1919	Missense	proximal	-1	no	5.199	5.361	EPSD	COSMIC	4.810	Up-regulation
CAMK_CAMK2_CAMK2A_ST	O95180	CACNA1H	Q9UQM7	CAMK2A	S1920	R1917H	1917	Missense	distal	-3	no	5.199	-0.298	EPSD	COSMIC	4.810	Loss
CAMK_CAMK2_CAMK2A_ST	O95180	CACNA1H	Q9UQM7	CAMK2A	S1920	V1921M	1921	Missense	proximal	1	no	5.199	5.310	EPSD	COSMIC	4.810	Up-regulation
CAMK_CAMK2_CAMK2A_ST	O95180	CACNA1H	Q9UQM7	CAMK2A	S1920	V1915M	1915	Missense	distal	-5	no	5.199	5.228	EPSD	COSMIC	4.810	Up-regulation
CAMK_CAMK2_CAMK2A_ST	O95180	CACNA1H	Q9UQM7	CAMK2A	S1926	V1919M	1919	Missense	distal	-7	no	8.009	7.779	EPSD	COSMIC	4.810	Down-regulation
CAMK_CAMK2_CAMK2A_ST	O95180	CACNA1H	Q9UQM7	CAMK2A	S1926	V1921M	1921	Missense	distal	-5	no	8.009	8.037	EPSD	COSMIC	4.810	Up-regulation
CAMK_CAMK2_CAMK2A_ST	O95180	CACNA1H	Q9UQM7	CAMK2A	T2073	V2067I	2067	Missense	distal	-6	no	6.781	6.716	EPSD	COSMIC	4.810	Down-regulation
CAMK_CAMK2_CAMK2A_ST	O95180	CACNA1H	Q9UQM7	CAMK2A	T2073	R2068C	2068	Missense	distal	-5	no	6.781	6.779	EPSD	COSMIC	4.810	Down-regulation
CAMK_CAMK2_CAMK2A_ST	O95180	CACNA1H	Q9UQM7	CAMK2A	T2073	G2075E	2075	Missense	proximal	2	no	6.781	7.699	EPSD	COSMIC	4.810	Up-regulation
CAMK_CAMK2_CAMK2A_ST	O95180	CACNA1H	Q9UQM7	CAMK2A	S2137	R2130Q	2130	Missense	distal	-7	no	8.990	9.047	EPSD	COSMIC	4.810	Up-regulation
CAMK_CAMK2_CAMK2A_ST	P78352	DLG4	Q9UQM7	CAMK2A	S73	A80T	80	Missense	distal	7	no	6.362	6.411	PhosphoSitePlus	COSMIC	4.810	Up-regulation
CAMK_CAMK2_CAMK2A_ST	P78352	DLG4	Q9UQM7	CAMK2A	T129	A133S	133	Missense	distal	4	no	4.971	5.024	EPSD	COSMIC	4.810	Up-regulation
CAMK_CAMK2_CAMK2A_ST	P78352	DLG4	Q9UQM7	CAMK2A	S295	S290R	290	Missense	distal	-5	no	8.527	8.456	EPSD	COSMIC	4.810	Down-regulation
CAMK_CAMK2_CAMK2A_ST	P78352	DLG4	Q9UQM7	CAMK2A	S295	S295R	295	Missense	central	0	yes	8.527	0.000	EPSD	COSMIC	4.810	Loss
CAMK_CAMK2_CAMK2A_ST	P78352	DLG4	Q9UQM7	CAMK2A	S295	P296L	296	Missense	proximal	1	no	8.527	9.186	EPSD	COSMIC	4.810	Up-regulation
CAMK_CAMK2_CAMK2A_ST	P78352	DLG4	Q9UQM7	CAMK2A	S295	R292W	292	Missense	distal	-3	no	8.527	-3.493	EPSD	COSMIC	4.810	Loss
CAMK_CAMK2_CAMK2A_ST	P78352	DLG4	Q9UQM7	CAMK2A	S295	S290F	290	Missense	distal	-5	no	8.527	8.545	EPSD	COSMIC	4.810	Up-regulation
CAMK_CAMK2_CAMK2A_ST	P78352	DLG4	Q9UQM7	CAMK2A	S295	R292Q	292	Missense	distal	-3	no	8.527	4.956	EPSD	COSMIC	4.810	Down-regulation
CAMK_CAMK2_CAMK2A_ST	P78352	DLG4	Q9UQM7	CAMK2A	S295	R293H	293	Missense	proximal	-2	no	8.527	8.407	EPSD	COSMIC;CCLE	4.810	Down-regulation
CAMK_CAMK2_CAMK2A_ST	P78352	DLG4	Q9UQM7	CAMK2A	S295	P296A	296	Missense	proximal	1	no	8.527	8.677	EPSD	COSMIC	4.810	Up-regulation
CAMK_CAMK2_CAMK2A_ST	P78352	DLG4	Q9UQM7	CAMK2A	S295	Y294F	294	Missense	proximal	-1	no	8.527	8.323	EPSD	COSMIC	4.810	Down-regulation
CAMK_CAMK2_CAMK2A_ST	P78352	DLG4	Q9UQM7	CAMK2A	S295	R293C	293	Missense	proximal	-2	no	8.527	7.724	EPSD	COSMIC	4.810	Down-regulation
CAMK_CAMK2_CAMK2A_ST	P78352	DLG4	Q9UQM7	CAMK2A	S453	R455C	455	Missense	proximal	2	no	5.039	4.593	EPSD	COSMIC	4.810	Loss
CAMK_CAMK2_CAMK2A_ST	P78352	DLG4	Q9UQM7	CAMK2A	S453	Q450H	450	Missense	distal	-3	no	5.039	3.113	EPSD	COSMIC	4.810	Loss
CAMK_CAMK2_CAMK2A_ST	P78352	DLG4	Q9UQM7	CAMK2A	S453	G457W	457	Missense	distal	4	no	5.039	4.673	EPSD	COSMIC	4.810	Loss
CAMK_CAMK2_CAMK2A_ST	P78352	DLG4	Q9UQM7	CAMK2A	S453	Q450L	450	Missense	distal	-3	no	5.039	3.488	EPSD	COSMIC	4.810	Loss
CAMK_CAMK2_CAMK2A_ST	P78352	DLG4	Q9UQM7	CAMK2A	S478	D483G	483	Missense	distal	5	no	7.225	7.166	EPSD	COSMIC	4.810	Down-regulation
CAMK_CAMK2_CAMK2A_ST	P78352	DLG4	Q9UQM7	CAMK2A	S478	W471R	471	Missense	distal	-7	no	7.225	6.481	EPSD	COSMIC	4.810	Down-regulation
CAMK_CAMK2_CAMK2A_ST	P78352	DLG4	Q9UQM7	CAMK2A	S478	D484N	484	Missense	distal	6	no	7.225	7.194	EPSD	COSMIC	4.810	Down-regulation
CAMK_CAMK2_CAMK2A_ST	P78352	DLG4	Q9UQM7	CAMK2A	S478	S480C	480	Missense	proximal	2	no	7.225	7.204	EPSD	COSMIC	4.810	Down-regulation
CAMK_CAMK2_CAMK2A_ST	P78352	DLG4	Q9UQM7	CAMK2A	S478	D483N	483	Missense	distal	5	no	7.225	7.237	EPSD	COSMIC	4.810	Up-regulation
CAMK_CAMK2_CAMK2A_ST	P78352	DLG4	Q9UQM7	CAMK2A	S478	V476G	476	Missense	proximal	-2	no	7.225	7.377	EPSD	COSMIC	4.810	Up-regulation
CAMK_CAMK2_CAMK2A_ST	P78352	DLG4	Q9UQM7	CAMK2A	S654	R651H	651	Missense	distal	-3	no	8.254	2.757	EPSD	COSMIC	4.810	Loss
CAMK_CAMK2_CAMK2A_ST	P78352	DLG4	Q9UQM7	CAMK2A	S654	R651C	651	Missense	distal	-3	no	8.254	2.673	EPSD	COSMIC	4.810	Loss
CAMK_CAMK2_CAMK2A_ST	P78352	DLG4	Q9UQM7	CAMK2A	S654	R653C	653	Missense	proximal	-1	no	8.254	7.926	EPSD	COSMIC	4.810	Down-regulation
CAMK_CAMK2_CAMK2A_ST	P78352	DLG4	Q9UQM7	CAMK2A	S654	V658A	658	Missense	distal	4	no	8.254	8.308	EPSD	COSMIC	4.810	Up-regulation
CAMK_CAMK2_CAMK2A_ST	P78352	DLG4	Q9UQM7	CAMK2A	S654	P652L	652	Missense	proximal	-2	no	8.254	8.144	EPSD	COSMIC	4.810	Down-regulation
CAMK_CAMK2_CAMK2A_ST	Q14457	BECN1	Q9UQM7	CAMK2A	S234	Q240H	240	Missense	distal	6	no	6.010	5.979	EPSD	COSMIC	4.810	Down-regulation
CAMK_CAMK2_CAMK2A_ST	Q14457	BECN1	Q9UQM7	CAMK2A	S412	T417N	417	Missense	distal	5	no	5.732	5.781	EPSD	COSMIC	4.810	Up-regulation
CAMK_CAMK2_CAMK2A_ST	Q13224	GRIN2B	Q9UQM7	CAMK2A	S930	R927Q	927	Missense	distal	-3	no	6.367	2.796	EPSD	COSMIC	4.810	Loss
CAMK_CAMK2_CAMK2A_ST	Q13224	GRIN2B	Q9UQM7	CAMK2A	S930	S930F	930	Missense	central	0	yes	6.367	0.000	EPSD	COSMIC	4.810	Loss
CAMK_CAMK2_CAMK2A_ST	Q13224	GRIN2B	Q9UQM7	CAMK2A	S1166	R1164H	1164	Missense	proximal	-2	no	5.799	5.679	EPSD	COSMIC	4.810	Down-regulation
CAMK_CAMK2_CAMK2A_ST	Q13224	GRIN2B	Q9UQM7	CAMK2A	S1166	D1165N	1165	Missense	proximal	-1	no	5.799	5.844	EPSD	COSMIC	4.810	Up-regulation
CAMK_CAMK2_CAMK2A_ST	Q13224	GRIN2B	Q9UQM7	CAMK2A	S1166	V1167I	1167	Missense	proximal	1	no	5.799	6.008	EPSD	COSMIC	4.810	Up-regulation
CAMK_CAMK2_CAMK2A_ST	Q13224	GRIN2B	Q9UQM7	CAMK2A	S1166	R1164S	1164	Missense	proximal	-2	no	5.799	5.728	EPSD	COSMIC	4.810	Down-regulation
CAMK_CAMK2_CAMK2A_ST	Q13224	GRIN2B	Q9UQM7	CAMK2A	S1303	S1303F	1303	Missense	central	0	yes	11.156	0.000	PhosphoSitePlus	COSMIC	4.810	Loss
CAMK_CAMK2_CAMK2A_ST	Q13224	GRIN2B	Q9UQM7	CAMK2A	S1303	D1309N	1309	Missense	distal	6	no	11.156	11.125	PhosphoSitePlus	COSMIC	4.810	Down-regulation
CAMK_CAMK2_CAMK2A_ST	Q13224	GRIN2B	Q9UQM7	CAMK2A	S1303	R1299L	1299	Missense	distal	-4	no	11.156	10.927	PhosphoSitePlus	COSMIC	4.810	Down-regulation
CAMK_CAMK2_CAMK2A_ST	Q13224	GRIN2B	Q9UQM7	CAMK2A	S1323	L1317M	1317	Missense	distal	-6	no	7.497	7.362	EPSD	COSMIC	4.810	Down-regulation
CAMK_CAMK2_CAMK2A_ST	Q13224	GRIN2B	Q9UQM7	CAMK2A	S1323	P1319T	1319	Missense	distal	-4	no	7.497	7.594	EPSD	COSMIC	4.810	Up-regulation
CAMK_CAMK2_CAMK2A_ST	Q13224	GRIN2B	Q9UQM7	CAMK2A	S1323	K1327N	1327	Missense	distal	4	no	7.497	7.464	EPSD	COSMIC	4.810	Down-regulation
CAMK_CAMK2_CAMK2A_ST	Q13224	GRIN2B	Q9UQM7	CAMK2A	S1323	V1322I	1322	Missense	proximal	-1	no	7.497	7.493	EPSD	COSMIC	4.810	Down-regulation
CAMK_CAMK2_CAMK2A_ST	Q13224	GRIN2B	Q9UQM7	CAMK2A	S1323	R1320C	1320	Missense	distal	-3	no	7.497	1.917	EPSD	COSMIC;CCLE	4.810	Loss
CAMK_CAMK2_CAMK2A_ST	Q13224	GRIN2B	Q9UQM7	CAMK2A	S1452	G1449R	1449	Missense	distal	-3	no	1.813	6.411	EPSD	COSMIC	4.810	Gain
CAMK_CAMK2_CAMK2A_ST	P42261	GRIA1	Q9UQM7	CAMK2A	S567	E564K	564	Missense	distal	-3	no	4.654	7.505	PhosphoSitePlus	COSMIC	4.810	Gain
CAMK_CAMK2_CAMK2A_ST	P42261	GRIA1	Q9UQM7	CAMK2A	S645	S645F	645	Missense	central	0	yes	8.892	0.000	EPSD	COSMIC	4.810	Loss
CAMK_CAMK2_CAMK2A_ST	P42261	GRIA1	Q9UQM7	CAMK2A	S834	E827G	827	Missense	distal	-7	no	4.697	4.985	EPSD	COSMIC	4.810	Gain
CAMK_CAMK2_CAMK2A_ST	P42261	GRIA1	Q9UQM7	CAMK2A	S834	Y830H	830	Missense	distal	-4	no	4.697	4.829	EPSD	COSMIC	4.810	Gain
CAMK_CAMK2_CAMK2A_ST	P42261	GRIA1	Q9UQM7	CAMK2A	S836	Y830H	830	Missense	distal	-6	no	7.793	7.672	EPSD	COSMIC	4.810	Down-regulation
CAMK_CAMK2_CAMK2A_ST	P42261	GRIA1	Q9UQM7	CAMK2A	S836	E835K	835	Missense	proximal	-1	no	7.793	7.612	EPSD	COSMIC	4.810	Down-regulation
CAMK_CAMK2_CAMK2A_ST	P42261	GRIA1	Q9UQM7	CAMK2A	S836	G841S	841	Missense	distal	5	no	7.793	7.977	EPSD	COSMIC	4.810	Up-regulation
CAMK_CAMK2_CAMK2A_ST	P42261	GRIA1	Q9UQM7	CAMK2A	S836	K831N	831	Missense	distal	-5	no	7.793	7.972	EPSD	COSMIC	4.810	Up-regulation
CAMK_CAMK2_CAMK2A_ST	P42261	GRIA1	Q9UQM7	CAMK2A	S849	R855Q	855	Missense	distal	6	no	5.595	5.601	EPSD	COSMIC	4.810	Up-regulation
CAMK_CAMK2_CAMK2A_ST	P42261	GRIA1	Q9UQM7	CAMK2A	S849	P846L	846	Missense	distal	-3	no	5.595	5.390	EPSD	COSMIC	4.810	Down-regulation
CAMK_CAMK2_CAMK2A_ST	P42261	GRIA1	Q9UQM7	CAMK2A	S849	P846Q	846	Missense	distal	-3	no	5.595	6.941	EPSD	COSMIC;GDSC	4.810	Up-regulation
CAMK_CAMK2_CAMK2A_ST	P42261	GRIA1	Q9UQM7	CAMK2A	T858	R855Q	855	Missense	distal	-3	no	6.756	3.185	EPSD	COSMIC	4.810	Loss
CAMK_CAMK2_CAMK2A_ST	P42261	GRIA1	Q9UQM7	CAMK2A	T858	S863N	863	Missense	distal	5	no	6.756	6.644	EPSD	COSMIC	4.810	Down-regulation
CAMK_CAMK2_CAMK2A_ST	P42261	GRIA1	Q9UQM7	CAMK2A	T858	L859F	859	Missense	proximal	1	no	6.756	6.650	EPSD	COSMIC	4.810	Down-regulation
CAMK_CAMK2_CAMK2A_ST	P42261	GRIA1	Q9UQM7	CAMK2A	T858	R861P	861	Missense	distal	3	no	6.756	6.579	EPSD	COSMIC	4.810	Down-regulation
CAMK_CAMK2_CAMK2A_ST	P37840	SNCA	Q9UQM7	CAMK2A	S9	A11S	11	Missense	proximal	2	no	5.363	5.324	EPSD	COSMIC	4.810	Down-regulation
CAMK_CAMK2_CAMK2A_ST	P10636	MAPT	Q9UQM7	CAMK2A	S113	I108V	108	Missense	distal	-5	no	4.846	4.932	EPSD	COSMIC	4.810	Up-regulation
CAMK_CAMK2_CAMK2A_ST	P10636	MAPT	Q9UQM7	CAMK2A	S113	G107R	107	Missense	distal	-6	no	4.846	4.709	EPSD	COSMIC	4.810	Loss
CAMK_CAMK2_CAMK2A_ST	P10636	MAPT	Q9UQM7	CAMK2A	T167	P160Q	160	Missense	distal	-7	no	5.827	5.722	EPSD	COSMIC	4.810	Down-regulation
CAMK_CAMK2_CAMK2A_ST	P10636	MAPT	Q9UQM7	CAMK2A	T167	A166V	166	Missense	proximal	-1	no	5.827	5.603	EPSD	COSMIC;CCLE	4.810	Down-regulation
CAMK_CAMK2_CAMK2A_ST	P10636	MAPT	Q9UQM7	CAMK2A	T167	E165K	165	Missense	proximal	-2	no	5.827	6.050	EPSD	COSMIC	4.810	Up-regulation
CAMK_CAMK2_CAMK2A_ST	P10636	MAPT	Q9UQM7	CAMK2A	T167	P160S	160	Missense	distal	-7	no	5.827	5.698	EPSD	COSMIC	4.810	Down-regulation
CAMK_CAMK2_CAMK2A_ST	P10636	MAPT	Q9UQM7	CAMK2A	T167	G172V	172	Missense	distal	5	no	5.827	5.843	EPSD	COSMIC	4.810	Up-regulation
CAMK_CAMK2_CAMK2A_ST	P10636	MAPT	Q9UQM7	CAMK2A	S171	P175S	175	Missense	distal	4	no	5.997	6.169	EPSD	COSMIC	4.810	Up-regulation
CAMK_CAMK2_CAMK2A_ST	P10636	MAPT	Q9UQM7	CAMK2A	S171	A166V	166	Missense	distal	-5	no	5.997	5.875	EPSD	COSMIC;CCLE	4.810	Down-regulation
CAMK_CAMK2_CAMK2A_ST	P10636	MAPT	Q9UQM7	CAMK2A	S171	E176G	176	Missense	distal	5	no	5.997	5.875	EPSD	COSMIC	4.810	Down-regulation
CAMK_CAMK2_CAMK2A_ST	P10636	MAPT	Q9UQM7	CAMK2A	S171	D177G	177	Missense	distal	6	no	5.997	5.907	EPSD	COSMIC	4.810	Down-regulation
CAMK_CAMK2_CAMK2A_ST	P10636	MAPT	Q9UQM7	CAMK2A	S171	E165K	165	Missense	distal	-6	no	5.997	6.097	EPSD	COSMIC	4.810	Up-regulation
CAMK_CAMK2_CAMK2A_ST	P10636	MAPT	Q9UQM7	CAMK2A	S171	G172V	172	Missense	proximal	1	no	5.997	6.629	EPSD	COSMIC	4.810	Up-regulation
CAMK_CAMK2_CAMK2A_ST	P10636	MAPT	Q9UQM7	CAMK2A	S214	E210Q	210	Missense	distal	-4	no	8.732	8.569	EPSD	COSMIC	4.810	Down-regulation
CAMK_CAMK2_CAMK2A_ST	P10636	MAPT	Q9UQM7	CAMK2A	S214	G207E	207	Missense	distal	-7	no	8.732	8.443	EPSD	COSMIC	4.810	Down-regulation
CAMK_CAMK2_CAMK2A_ST	P10636	MAPT	Q9UQM7	CAMK2A	S318	G323R	323	Missense	distal	5	no	6.384	6.426	EPSD	COSMIC	4.810	Up-regulation
CAMK_CAMK2_CAMK2A_ST	P10636	MAPT	Q9UQM7	CAMK2A	S341	A337T	337	Missense	distal	-4	no	7.485	7.195	EPSD	COSMIC	4.810	Down-regulation
CAMK_CAMK2_CAMK2A_ST	P10636	MAPT	Q9UQM7	CAMK2A	S341	G343R	343	Missense	proximal	2	no	7.485	7.904	EPSD	COSMIC	4.810	Up-regulation
CAMK_CAMK2_CAMK2A_ST	P10636	MAPT	Q9UQM7	CAMK2A	S341	D345G	345	Missense	distal	4	no	7.485	7.495	EPSD	COSMIC	4.810	Up-regulation
CAMK_CAMK2_CAMK2A_ST	P10636	MAPT	Q9UQM7	CAMK2A	S341	K347N	347	Missense	distal	6	no	7.485	7.515	EPSD	COSMIC	4.810	Up-regulation
CAMK_CAMK2_CAMK2A_ST	P10636	MAPT	Q9UQM7	CAMK2A	S369	V368I	368	Missense	proximal	-1	no	5.352	5.348	EPSD	COSMIC	4.810	Down-regulation
CAMK_CAMK2_CAMK2A_ST	P10636	MAPT	Q9UQM7	CAMK2A	S369	R370W	370	Missense	proximal	1	no	5.352	5.062	EPSD	COSMIC	4.810	Down-regulation
CAMK_CAMK2_CAMK2A_ST	P10636	MAPT	Q9UQM7	CAMK2A	S382	G385V	385	Missense	distal	3	no	4.976	5.105	EPSD	COSMIC	4.810	Up-regulation
CAMK_CAMK2_CAMK2A_ST	P10636	MAPT	Q9UQM7	CAMK2A	S382	T386I	386	Missense	distal	4	no	4.976	4.804	EPSD	COSMIC	4.810	Loss
CAMK_CAMK2_CAMK2A_ST	P10636	MAPT	Q9UQM7	CAMK2A	S382	R377W	377	Missense	distal	-5	no	4.976	5.124	EPSD	COSMIC	4.810	Up-regulation
CAMK_CAMK2_CAMK2A_ST	P10636	MAPT	Q9UQM7	CAMK2A	S382	D389N	389	Missense	distal	7	no	4.976	4.958	EPSD	COSMIC;GDSC;CCLE	4.810	Down-regulation
CAMK_CAMK2_CAMK2A_ST	P10636	MAPT	Q9UQM7	CAMK2A	S388	G385V	385	Missense	distal	-3	no	5.329	4.805	EPSD	COSMIC	4.810	Loss
CAMK_CAMK2_CAMK2A_ST	P10636	MAPT	Q9UQM7	CAMK2A	S388	T386I	386	Missense	proximal	-2	no	5.329	5.304	EPSD	COSMIC	4.810	Down-regulation
CAMK_CAMK2_CAMK2A_ST	P10636	MAPT	Q9UQM7	CAMK2A	S388	D389N	389	Missense	proximal	1	no	5.329	5.215	EPSD	COSMIC;GDSC;CCLE	4.810	Down-regulation
CAMK_CAMK2_CAMK2A_ST	P10636	MAPT	Q9UQM7	CAMK2A	S451	S447P	447	Missense	distal	-4	no	8.319	7.941	EPSD	COSMIC	4.810	Down-regulation
CAMK_CAMK2_CAMK2A_ST	P10636	MAPT	Q9UQM7	CAMK2A	S451	R448Q	448	Missense	distal	-3	no	8.319	4.748	EPSD	COSMIC	4.810	Loss
CAMK_CAMK2_CAMK2A_ST	P10636	MAPT	Q9UQM7	CAMK2A	T470	T466M	466	Missense	distal	-4	no	5.245	5.301	EPSD	COSMIC;GDSC;CCLE	4.810	Up-regulation
CAMK_CAMK2_CAMK2A_ST	P10636	MAPT	Q9UQM7	CAMK2A	T470	K467T	467	Missense	distal	-3	no	5.245	2.456	EPSD	COSMIC	4.810	Loss
CAMK_CAMK2_CAMK2A_ST	P10636	MAPT	Q9UQM7	CAMK2A	T470	P477L	477	Missense	distal	7	no	5.245	5.310	EPSD	COSMIC	4.810	Up-regulation
CAMK_CAMK2_CAMK2A_ST	P10636	MAPT	Q9UQM7	CAMK2A	T470	P477S	477	Missense	distal	7	no	5.245	5.146	EPSD	COSMIC	4.810	Down-regulation
CAMK_CAMK2_CAMK2A_ST	P10636	MAPT	Q9UQM7	CAMK2A	S508	G509V	509	Missense	proximal	1	no	4.477	5.110	EPSD	COSMIC	4.810	Gain
CAMK_CAMK2_CAMK2A_ST	P10636	MAPT	Q9UQM7	CAMK2A	T529	R526H	526	Missense	distal	-3	no	6.612	1.114	EPSD	COSMIC	4.810	Loss
CAMK_CAMK2_CAMK2A_ST	P10636	MAPT	Q9UQM7	CAMK2A	T529	R528S	528	Missense	proximal	-1	no	6.612	6.700	EPSD	COSMIC	4.810	Up-regulation
CAMK_CAMK2_CAMK2A_ST	P10636	MAPT	Q9UQM7	CAMK2A	T529	P530S	530	Missense	proximal	1	no	6.612	6.979	EPSD	COSMIC	4.810	Up-regulation
CAMK_CAMK2_CAMK2A_ST	P10636	MAPT	Q9UQM7	CAMK2A	T529	P536H	536	Missense	distal	7	no	6.612	6.569	EPSD	COSMIC	4.810	Down-regulation
CAMK_CAMK2_CAMK2A_ST	P10636	MAPT	Q9UQM7	CAMK2A	T529	P535Q	535	Missense	distal	6	no	6.612	6.703	EPSD	COSMIC	4.810	Up-regulation
CAMK_CAMK2_CAMK2A_ST	P10636	MAPT	Q9UQM7	CAMK2A	S531	R526H	526	Missense	distal	-5	no	6.480	6.426	EPSD	COSMIC	4.810	Down-regulation
CAMK_CAMK2_CAMK2A_ST	P10636	MAPT	Q9UQM7	CAMK2A	S531	R528S	528	Missense	distal	-3	no	6.480	2.020	EPSD	COSMIC	4.810	Loss
CAMK_CAMK2_CAMK2A_ST	P10636	MAPT	Q9UQM7	CAMK2A	S531	P530S	530	Missense	proximal	-1	no	6.480	6.666	EPSD	COSMIC	4.810	Up-regulation
CAMK_CAMK2_CAMK2A_ST	P10636	MAPT	Q9UQM7	CAMK2A	S531	P536H	536	Missense	distal	5	no	6.480	6.683	EPSD	COSMIC	4.810	Up-regulation
CAMK_CAMK2_CAMK2A_ST	P10636	MAPT	Q9UQM7	CAMK2A	S531	P535Q	535	Missense	distal	4	no	6.480	6.650	EPSD	COSMIC	4.810	Up-regulation
CAMK_CAMK2_CAMK2A_ST	P10636	MAPT	Q9UQM7	CAMK2A	S554	P550S	550	Missense	distal	-4	no	5.018	5.396	EPSD	COSMIC	4.810	Up-regulation
CAMK_CAMK2_CAMK2A_ST	P10636	MAPT	Q9UQM7	CAMK2A	S554	R559C	559	Missense	distal	5	no	5.018	4.725	EPSD	COSMIC	4.810	Loss
CAMK_CAMK2_CAMK2A_ST	P10636	MAPT	Q9UQM7	CAMK2A	S554	P553R	553	Missense	proximal	-1	no	5.018	5.116	EPSD	COSMIC	4.810	Up-regulation
CAMK_CAMK2_CAMK2A_ST	P10636	MAPT	Q9UQM7	CAMK2A	S554	P553L	553	Missense	proximal	-1	no	5.018	4.993	EPSD	COSMIC	4.810	Down-regulation
CAMK_CAMK2_CAMK2A_ST	P10636	MAPT	Q9UQM7	CAMK2A	S554	P549L	549	Missense	distal	-5	no	5.018	4.925	EPSD	COSMIC	4.810	Down-regulation
CAMK_CAMK2_CAMK2A_ST	P10636	MAPT	Q9UQM7	CAMK2A	S554	S555F	555	Missense	proximal	1	no	5.018	5.203	EPSD	COSMIC	4.810	Up-regulation
CAMK_CAMK2_CAMK2A_ST	P10636	MAPT	Q9UQM7	CAMK2A	S554	P553Q	553	Missense	proximal	-1	no	5.018	5.360	EPSD	COSMIC	4.810	Up-regulation
CAMK_CAMK2_CAMK2A_ST	P10636	MAPT	Q9UQM7	CAMK2A	T562	V565M	565	Missense	distal	3	no	5.947	5.788	EPSD	COSMIC	4.810	Down-regulation
CAMK_CAMK2_CAMK2A_ST	P10636	MAPT	Q9UQM7	CAMK2A	T562	P566S	566	Missense	distal	4	no	5.947	6.120	EPSD	COSMIC	4.810	Up-regulation
CAMK_CAMK2_CAMK2A_ST	P10636	MAPT	Q9UQM7	CAMK2A	T562	R559C	559	Missense	distal	-3	no	5.947	0.366	EPSD	COSMIC	4.810	Loss
CAMK_CAMK2_CAMK2A_ST	P10636	MAPT	Q9UQM7	CAMK2A	T562	S555F	555	Missense	distal	-7	no	5.947	6.508	EPSD	COSMIC	4.810	Up-regulation
CAMK_CAMK2_CAMK2A_ST	P10636	MAPT	Q9UQM7	CAMK2A	T562	P568S	568	Missense	distal	6	no	5.947	6.030	EPSD	COSMIC	4.810	Up-regulation
CAMK_CAMK2_CAMK2A_ST	P10636	MAPT	Q9UQM7	CAMK2A	S579	T580N	580	Missense	proximal	1	no	6.153	5.728	EPSD	COSMIC	4.810	Down-regulation
CAMK_CAMK2_CAMK2A_ST	P10636	MAPT	Q9UQM7	CAMK2A	S579	G578S	578	Missense	proximal	-1	no	6.153	6.299	EPSD	COSMIC	4.810	Up-regulation
CAMK_CAMK2_CAMK2A_ST	P10636	MAPT	Q9UQM7	CAMK2A	S610	N613D	613	Missense	distal	3	no	6.110	6.238	EPSD	COSMIC	4.810	Up-regulation
CAMK_CAMK2_CAMK2A_ST	P10636	MAPT	Q9UQM7	CAMK2A	S610	C608W	608	Missense	proximal	-2	no	6.110	6.095	EPSD	COSMIC	4.810	Down-regulation
CAMK_CAMK2_CAMK2A_ST	P10636	MAPT	Q9UQM7	CAMK2A	S610	S610L	610	Missense	central	0	yes	6.110	0.000	EPSD	COSMIC	4.810	Loss
CAMK_CAMK2_CAMK2A_ST	P10636	MAPT	Q9UQM7	CAMK2A	S669	S669L	669	Missense	central	0	yes	7.992	0.000	EPSD	COSMIC	4.810	Loss
CAMK_CAMK2_CAMK2A_ST	P10636	MAPT	Q9UQM7	CAMK2A	S669	R666K	666	Missense	distal	-3	no	7.992	5.724	EPSD	COSMIC	4.810	Down-regulation
CAMK_CAMK2_CAMK2A_ST	P10636	MAPT	Q9UQM7	CAMK2A	S669	D662G	662	Missense	distal	-7	no	7.992	8.080	EPSD	COSMIC	4.810	Up-regulation
CAMK_CAMK2_CAMK2A_ST	P10636	MAPT	Q9UQM7	CAMK2A	S669	S673F	673	Missense	distal	4	no	7.992	7.834	EPSD	COSMIC	4.810	Down-regulation
CAMK_CAMK2_CAMK2A_ST	P10636	MAPT	Q9UQM7	CAMK2A	S669	K670N	670	Missense	proximal	1	no	7.992	7.619	EPSD	COSMIC	4.810	Down-regulation
CAMK_CAMK2_CAMK2A_ST	P10636	MAPT	Q9UQM7	CAMK2A	S669	K664N	664	Missense	distal	-5	no	7.992	8.171	EPSD	COSMIC	4.810	Up-regulation
CAMK_CAMK2_CAMK2A_ST	P10636	MAPT	Q9UQM7	CAMK2A	S669	L674Q	674	Missense	distal	5	no	7.992	8.139	EPSD	COSMIC	4.810	Up-regulation
CAMK_CAMK2_CAMK2A_ST	P10636	MAPT	Q9UQM7	CAMK2A	S673	V680I	680	Missense	distal	7	no	4.973	5.088	EPSD	COSMIC	4.810	Up-regulation
CAMK_CAMK2_CAMK2A_ST	P10636	MAPT	Q9UQM7	CAMK2A	S673	S669L	669	Missense	distal	-4	no	4.973	4.675	EPSD	COSMIC	4.810	Loss
CAMK_CAMK2_CAMK2A_ST	P10636	MAPT	Q9UQM7	CAMK2A	S673	R666K	666	Missense	distal	-7	no	4.973	4.907	EPSD	COSMIC	4.810	Down-regulation
CAMK_CAMK2_CAMK2A_ST	P10636	MAPT	Q9UQM7	CAMK2A	S673	S673F	673	Missense	central	0	yes	4.973	0.000	EPSD	COSMIC	4.810	Loss
CAMK_CAMK2_CAMK2A_ST	P10636	MAPT	Q9UQM7	CAMK2A	S673	K670N	670	Missense	distal	-3	no	4.973	2.406	EPSD	COSMIC	4.810	Loss
CAMK_CAMK2_CAMK2A_ST	P10636	MAPT	Q9UQM7	CAMK2A	S673	L674Q	674	Missense	proximal	1	no	4.973	4.467	EPSD	COSMIC	4.810	Loss
CAMK_CAMK2_CAMK2A_ST	P10636	MAPT	Q9UQM7	CAMK2A	T690	R696H	696	Missense	distal	6	no	5.043	5.017	EPSD	COSMIC	4.810	Down-regulation
CAMK_CAMK2_CAMK2A_ST	P10636	MAPT	Q9UQM7	CAMK2A	T690	G683R	683	Missense	distal	-7	no	5.043	4.711	EPSD	COSMIC;CCLE	4.810	Loss
CAMK_CAMK2_CAMK2A_ST	P10636	MAPT	Q9UQM7	CAMK2A	T690	G683E	683	Missense	distal	-7	no	5.043	4.754	EPSD	COSMIC	4.810	Loss
CAMK_CAMK2_CAMK2A_ST	P10636	MAPT	Q9UQM7	CAMK2A	T690	R696C	696	Missense	distal	6	no	5.043	4.878	EPSD	COSMIC	4.810	Down-regulation
CAMK_CAMK2_CAMK2A_ST	P10636	MAPT	Q9UQM7	CAMK2A	T690	G684E	684	Missense	distal	-6	no	5.043	4.833	EPSD	COSMIC	4.810	Down-regulation
CAMK_CAMK2_CAMK2A_ST	P10636	MAPT	Q9UQM7	CAMK2A	S726	G732S	732	Missense	distal	6	no	6.647	6.706	EPSD	COSMIC	4.810	Up-regulation
CAMK_CAMK2_CAMK2A_ST	P10636	MAPT	Q9UQM7	CAMK2A	S726	G732C	732	Missense	distal	6	no	6.647	6.543	EPSD	COSMIC	4.810	Down-regulation
CAMK_CAMK2_CAMK2A_ST	P10636	MAPT	Q9UQM7	CAMK2A	S726	R723W	723	Missense	distal	-3	no	6.647	-5.374	EPSD	COSMIC	4.810	Loss
CAMK_CAMK2_CAMK2A_ST	P10636	MAPT	Q9UQM7	CAMK2A	S726	V728M	728	Missense	proximal	2	no	6.647	6.720	EPSD	COSMIC	4.810	Up-regulation
CAMK_CAMK2_CAMK2A_ST	P10636	MAPT	Q9UQM7	CAMK2A	S726	V728A	728	Missense	proximal	2	no	6.647	6.661	EPSD	COSMIC	4.810	Up-regulation
CAMK_CAMK2_CAMK2A_ST	P10636	MAPT	Q9UQM7	CAMK2A	S733	G732S	732	Missense	proximal	-1	no	7.015	7.161	EPSD	COSMIC	4.810	Up-regulation
CAMK_CAMK2_CAMK2A_ST	P10636	MAPT	Q9UQM7	CAMK2A	S733	D735N	735	Missense	proximal	2	no	7.015	6.004	EPSD	COSMIC	4.810	Down-regulation
CAMK_CAMK2_CAMK2A_ST	P10636	MAPT	Q9UQM7	CAMK2A	S733	G732C	732	Missense	proximal	-1	no	7.015	6.745	EPSD	COSMIC	4.810	Down-regulation
CAMK_CAMK2_CAMK2A_ST	P10636	MAPT	Q9UQM7	CAMK2A	S733	V728M	728	Missense	distal	-5	no	7.015	7.044	EPSD	COSMIC	4.810	Up-regulation
CAMK_CAMK2_CAMK2A_ST	P10636	MAPT	Q9UQM7	CAMK2A	S733	V728A	728	Missense	distal	-5	no	7.015	7.137	EPSD	COSMIC	4.810	Up-regulation
CAMK_CAMK2_CAMK2A_ST	P26678	PLN	Q9UQM7	CAMK2A	S16	E19K	19	Missense	distal	3	no	9.816	9.651	EPSD	COSMIC	4.810	Down-regulation
CAMK_CAMK2_CAMK2A_ST	P26678	PLN	Q9UQM7	CAMK2A	S16	T17I	17	Missense	proximal	1	no	9.816	10.277	EPSD	COSMIC	4.810	Up-regulation
CAMK_CAMK2_CAMK2A_ST	P26678	PLN	Q9UQM7	CAMK2A	S16	I18T	18	Missense	proximal	2	no	9.816	9.260	EPSD	COSMIC	4.810	Down-regulation
CAMK_CAMK2_CAMK2A_ST	P26678	PLN	Q9UQM7	CAMK2A	T17	E19K	19	Missense	proximal	2	no	9.546	7.505	PhosphoSitePlus	COSMIC	4.810	Down-regulation
CAMK_CAMK2_CAMK2A_ST	P26678	PLN	Q9UQM7	CAMK2A	T17	T17I	17	Missense	central	0	yes	9.546	0.000	PhosphoSitePlus	COSMIC	4.810	Loss
CAMK_CAMK2_CAMK2A_ST	P26678	PLN	Q9UQM7	CAMK2A	T17	I18T	18	Missense	proximal	1	no	9.546	9.086	PhosphoSitePlus	COSMIC	4.810	Down-regulation
Other_Aur_AURKA_ST	Q14194	CRMP1	O14965	AURKA	T101	L97M	97	Missense	distal	-4	no	43.523	43.466	PhosphoSitePlus;EPSD	COSMIC	39.062	Down-regulation
Other_Aur_AURKA_ST	Q14194	CRMP1	O14965	AURKA	T101	T101N	101	Missense	central	0	yes	43.523	0.000	PhosphoSitePlus;EPSD	COSMIC	39.062	Loss
Other_Aur_AURKA_ST	Q14194	CRMP1	O14965	AURKA	T102	L97M	97	Missense	distal	-5	no	50.086	50.113	EPSD;PhosphoSitePlus	COSMIC	39.062	Up-regulation
Other_Aur_AURKA_ST	Q14194	CRMP1	O14965	AURKA	T102	T101N	101	Missense	proximal	-1	no	50.086	46.544	EPSD;PhosphoSitePlus	COSMIC	39.062	Down-regulation
Other_Aur_AURKA_ST	Q14194	CRMP1	O14965	AURKA	S385	K390N	390	Missense	distal	5	no	40.161	39.238	EPSD	COSMIC	39.062	Down-regulation
Other_Aur_AURKA_ST	Q14194	CRMP1	O14965	AURKA	S522	S522L	522	Missense	central	0	yes	39.447	0.000	EPSD	COSMIC	39.062	Loss
Other_Aur_AURKA_ST	Q14194	CRMP1	O14965	AURKA	S522	S521Y	521	Missense	proximal	-1	no	39.447	38.504	EPSD	COSMIC	39.062	Loss
Other_Aur_AURKA_ST	Q14194	CRMP1	O14965	AURKA	S522	P515L	515	Missense	distal	-7	no	39.447	37.775	EPSD	COSMIC	39.062	Loss
Other_Aur_AURKA_ST	Q14194	CRMP1	O14965	AURKA	S522	Q527H	527	Missense	distal	5	no	39.447	37.576	EPSD	COSMIC;CCLE	39.062	Loss
Other_Aur_AURKA_ST	Q14194	CRMP1	O14965	AURKA	S522	P528T	528	Missense	distal	6	no	39.447	39.407	EPSD	COSMIC	39.062	Down-regulation
Other_Aur_AURKA_ST	Q14194	CRMP1	O14965	AURKA	S522	P528L	528	Missense	distal	6	no	39.447	39.440	EPSD	COSMIC	39.062	Down-regulation
Other_Aur_AURKA_ST	Q14194	CRMP1	O14965	AURKA	S522	A516V	516	Missense	distal	-6	no	39.447	38.611	EPSD	COSMIC	39.062	Loss
Other_Aur_AURKA_ST	Q14194	CRMP1	O14965	AURKA	S540	L541F	541	Missense	proximal	1	no	38.317	39.147	EPSD	COSMIC	39.062	Gain
Other_Aur_AURKA_ST	Q14194	CRMP1	O14965	AURKA	S542	F539V	539	Missense	distal	-3	no	32.450	39.383	EPSD	COSMIC	39.062	Gain
Other_Aur_AURKA_ST	O43379	WDR62	O14965	AURKA	S211	F206L	206	Missense	distal	-5	no	41.116	41.101	EPSD	COSMIC	39.062	Down-regulation
Other_Aur_AURKA_ST	O43379	WDR62	O14965	AURKA	S211	L204H	204	Missense	distal	-7	no	41.116	40.027	EPSD	COSMIC	39.062	Down-regulation
Other_Aur_AURKA_ST	O43379	WDR62	O14965	AURKA	T781	P777S	777	Missense	distal	-4	no	38.472	40.389	EPSD	COSMIC	39.062	Gain
Other_Aur_AURKA_ST	O43379	WDR62	O14965	AURKA	S1093	T1096M	1096	Missense	distal	3	no	40.705	43.169	EPSD	COSMIC	39.062	Up-regulation
Other_Aur_AURKA_ST	O43379	WDR62	O14965	AURKA	S1093	P1090I	1090	Missense	distal	-3	no	40.705	41.094	EPSD	COSMIC	39.062	Up-regulation
Other_Aur_AURKA_ST	O43379	WDR62	O14965	AURKA	S1095	T1096M	1096	Missense	proximal	1	no	47.133	48.624	EPSD	COSMIC	39.062	Up-regulation
Other_Aur_AURKA_ST	O43379	WDR62	O14965	AURKA	S1095	P1090I	1090	Missense	distal	-5	no	47.133	47.153	EPSD	COSMIC	39.062	Up-regulation
Other_Aur_AURKA_ST	O43379	WDR62	O14965	AURKA	S1208	A1206V	1206	Missense	proximal	-2	no	40.600	41.198	EPSD	COSMIC	39.062	Up-regulation
Other_Aur_AURKA_ST	O43379	WDR62	O14965	AURKA	S1224	G1230C	1230	Missense	distal	6	no	57.772	57.585	EPSD	COSMIC	39.062	Down-regulation
Other_Aur_AURKA_ST	O43379	WDR62	O14965	AURKA	S1224	G1230S	1230	Missense	distal	6	no	57.772	57.774	EPSD	COSMIC	39.062	Up-regulation
Other_Aur_AURKA_ST	O43379	WDR62	O14965	AURKA	S1224	S1218N	1218	Missense	distal	-6	no	57.772	60.977	EPSD	COSMIC	39.062	Up-regulation
Other_Aur_AURKA_ST	O43379	WDR62	O14965	AURKA	S1224	R1220C	1220	Missense	distal	-4	no	57.772	54.572	EPSD	COSMIC	39.062	Down-regulation
Other_Aur_AURKA_ST	O43379	WDR62	O14965	AURKA	S1224	R1225C	1225	Missense	proximal	1	no	57.772	52.639	EPSD	COSMIC	39.062	Down-regulation
Other_Aur_AURKA_ST	O43379	WDR62	O14965	AURKA	S1228	G1230C	1230	Missense	proximal	2	no	47.489	49.272	EPSD	COSMIC	39.062	Up-regulation
Other_Aur_AURKA_ST	O43379	WDR62	O14965	AURKA	S1228	S1232N	1232	Missense	distal	4	no	47.489	46.615	EPSD	COSMIC	39.062	Down-regulation
Other_Aur_AURKA_ST	O43379	WDR62	O14965	AURKA	S1228	G1230S	1230	Missense	proximal	2	no	47.489	47.324	EPSD	COSMIC	39.062	Down-regulation
Other_Aur_AURKA_ST	O43379	WDR62	O14965	AURKA	S1228	R1225C	1225	Missense	distal	-3	no	47.489	42.953	EPSD	COSMIC	39.062	Down-regulation
Other_Aur_AURKA_ST	O43379	WDR62	O14965	AURKA	S1248	S1248P	1248	Missense	central	0	yes	47.027	0.000	EPSD	COSMIC	39.062	Loss
Other_Aur_AURKA_ST	O43379	WDR62	O14965	AURKA	S1248	G1251R	1251	Missense	distal	3	no	47.027	46.368	EPSD	COSMIC	39.062	Down-regulation
Other_Aur_AURKA_ST	O43379	WDR62	O14965	AURKA	S1248	S1248L	1248	Missense	central	0	yes	47.027	0.000	EPSD	COSMIC;CCLE	39.062	Loss
Other_Aur_AURKA_ST	O43379	WDR62	O14965	AURKA	S1249	S1248P	1248	Missense	proximal	-1	no	41.699	41.485	EPSD	COSMIC	39.062	Down-regulation
Other_Aur_AURKA_ST	O43379	WDR62	O14965	AURKA	S1249	G1251R	1251	Missense	proximal	2	no	41.699	40.328	EPSD	COSMIC	39.062	Down-regulation
Other_Aur_AURKA_ST	O43379	WDR62	O14965	AURKA	S1249	S1248L	1248	Missense	proximal	-1	no	41.699	40.130	EPSD	COSMIC;CCLE	39.062	Down-regulation
Other_Aur_AURKA_ST	O43379	WDR62	O14965	AURKA	S1255	S1248P	1248	Missense	distal	-7	no	44.098	45.958	EPSD	COSMIC	39.062	Up-regulation
Other_Aur_AURKA_ST	O43379	WDR62	O14965	AURKA	S1255	G1251R	1251	Missense	distal	-4	no	44.098	44.416	EPSD	COSMIC	39.062	Up-regulation
Other_Aur_AURKA_ST	O43379	WDR62	O14965	AURKA	S1255	S1248L	1248	Missense	distal	-7	no	44.098	44.285	EPSD	COSMIC;CCLE	39.062	Up-regulation
Other_Aur_AURKA_ST	O43379	WDR62	O14965	AURKA	S1320	P1317H	1317	Missense	distal	-3	no	37.804	40.690	EPSD	COSMIC	39.062	Gain
Other_Aur_AURKA_ST	O43379	WDR62	O14965	AURKA	S1320	P1317S	1317	Missense	distal	-3	no	37.804	39.984	EPSD	COSMIC	39.062	Gain
Other_Aur_AURKA_ST	O43379	WDR62	O14965	AURKA	S1435	R1431H	1431	Missense	distal	-4	no	41.817	37.381	EPSD	COSMIC	39.062	Loss
Other_Aur_AURKA_ST	Q9UNN5	FAF1	O14965	AURKA	S212	I217V	217	Missense	distal	5	no	43.863	42.105	EPSD	COSMIC;GDSC;CCLE	39.062	Down-regulation
Other_Aur_AURKA_ST	Q9UNN5	FAF1	O14965	AURKA	S212	G213L	213	Missense	proximal	1	no	43.863	47.112	EPSD	COSMIC	39.062	Up-regulation
Other_Aur_AURKA_ST	Q9UNN5	FAF1	O14965	AURKA	T264	R268I	268	Missense	distal	4	no	42.901	44.019	EPSD	COSMIC;GDSC;CCLE	39.062	Up-regulation
Other_Aur_AURKA_ST	Q9UNN5	FAF1	O14965	AURKA	S269	E276G	276	Missense	distal	7	no	39.220	39.291	EPSD	COSMIC	39.062	Up-regulation
Other_Aur_AURKA_ST	Q9UNN5	FAF1	O14965	AURKA	S269	R268I	268	Missense	proximal	-1	no	39.220	40.725	EPSD	COSMIC;GDSC;CCLE	39.062	Up-regulation
Other_Aur_AURKA_ST	Q9UNN5	FAF1	O14965	AURKA	S270	E276G	276	Missense	distal	6	no	41.982	42.041	EPSD	COSMIC	39.062	Up-regulation
Other_Aur_AURKA_ST	Q9UNN5	FAF1	O14965	AURKA	S270	R268I	268	Missense	proximal	-2	no	41.982	22.953	EPSD	COSMIC;GDSC;CCLE	39.062	Loss
Other_Aur_AURKA_ST	Q9UNN5	FAF1	O14965	AURKA	S556	L561P	561	Missense	distal	5	no	42.981	43.565	EPSD	COSMIC	39.062	Up-regulation
Other_Aur_AURKA_ST	Q9UNN5	FAF1	O14965	AURKA	S556	E558Q	558	Missense	proximal	2	no	42.981	43.321	EPSD	COSMIC	39.062	Up-regulation
Other_Aur_AURKA_ST	O14965	AURKA	O14965	AURKA	S41	A44S	44	Missense	distal	3	no	45.936	47.391	EPSD;PhosphoSitePlus	COSMIC	39.062	Up-regulation
Other_Aur_AURKA_ST	O14965	AURKA	O14965	AURKA	S41	G42D	42	Missense	proximal	1	no	45.936	47.613	EPSD;PhosphoSitePlus	COSMIC	39.062	Up-regulation
Other_Aur_AURKA_ST	O14965	AURKA	O14965	AURKA	S41	L37F	37	Missense	distal	-4	no	45.936	42.653	EPSD;PhosphoSitePlus	COSMIC	39.062	Down-regulation
Other_Aur_AURKA_ST	O14965	AURKA	O14965	AURKA	S41	L37I	37	Missense	distal	-4	no	45.936	40.992	EPSD;PhosphoSitePlus	COSMIC	39.062	Down-regulation
Other_Aur_AURKA_ST	O14965	AURKA	O14965	AURKA	S51	A44S	44	Missense	distal	-7	no	40.549	40.664	EPSD	COSMIC	39.062	Up-regulation
Other_Aur_AURKA_ST	O14965	AURKA	O14965	AURKA	S51	S54F	54	Missense	distal	3	no	40.549	40.603	EPSD	COSMIC	39.062	Up-regulation
Other_Aur_AURKA_ST	O14965	AURKA	O14965	AURKA	S51	Q55L	55	Missense	distal	4	no	40.549	40.759	EPSD	COSMIC	39.062	Up-regulation
Other_Aur_AURKA_ST	O14965	AURKA	O14965	AURKA	S51	S53F	53	Missense	proximal	2	no	40.549	39.853	EPSD	COSMIC	39.062	Down-regulation
Other_Aur_AURKA_ST	O14965	AURKA	O14965	AURKA	S51	P58S	58	Missense	distal	7	no	40.549	40.658	EPSD	COSMIC	39.062	Up-regulation
Other_Aur_AURKA_ST	O14965	AURKA	O14965	AURKA	S51	S51L	51	Missense	central	0	yes	40.549	0.000	EPSD	COSMIC	39.062	Loss
Other_Aur_AURKA_ST	O14965	AURKA	O14965	AURKA	S67	K63N	63	Missense	distal	-4	no	44.094	43.738	PhosphoSitePlus;EPSD	COSMIC	39.062	Down-regulation
Other_Aur_AURKA_ST	O14965	AURKA	O14965	AURKA	S67	H68D	68	Missense	proximal	1	no	44.094	46.940	PhosphoSitePlus;EPSD	COSMIC	39.062	Up-regulation
Other_Aur_AURKA_ST	O14965	AURKA	O14965	AURKA	S83	A81T	81	Missense	proximal	-2	no	43.988	36.413	EPSD;PhosphoSitePlus	COSMIC	39.062	Loss
Other_Aur_AURKA_ST	O14965	AURKA	O14965	AURKA	S83	H86Y	86	Missense	distal	3	no	43.988	45.307	EPSD;PhosphoSitePlus	COSMIC	39.062	Up-regulation
Other_Aur_AURKA_ST	O14965	AURKA	O14965	AURKA	S83	P87L	87	Missense	distal	4	no	43.988	44.135	EPSD;PhosphoSitePlus	COSMIC	39.062	Up-regulation
Other_Aur_AURKA_ST	O14965	AURKA	O14965	AURKA	S83	R90M	90	Missense	distal	7	no	43.988	43.965	EPSD;PhosphoSitePlus	COSMIC	39.062	Down-regulation
Other_Aur_AURKA_ST	O14965	AURKA	O14965	AURKA	S83	P85S	85	Missense	proximal	2	no	43.988	45.236	EPSD;PhosphoSitePlus	COSMIC	39.062	Up-regulation
Other_Aur_AURKA_ST	O14965	AURKA	O14965	AURKA	S98	S98R	98	Missense	central	0	yes	45.902	0.000	EPSD;PhosphoSitePlus	COSMIC	39.062	Loss
Other_Aur_AURKA_ST	O14965	AURKA	O14965	AURKA	S98	P91L	91	Missense	distal	-7	no	45.902	44.230	EPSD;PhosphoSitePlus	COSMIC	39.062	Down-regulation
Other_Aur_AURKA_ST	O14965	AURKA	O14965	AURKA	S98	Q100L	100	Missense	proximal	2	no	45.902	44.129	EPSD;PhosphoSitePlus	COSMIC	39.062	Down-regulation
Other_Aur_AURKA_ST	O14965	AURKA	O14965	AURKA	S98	P91Q	91	Missense	distal	-7	no	45.902	44.093	EPSD;PhosphoSitePlus	COSMIC	39.062	Down-regulation
Other_Aur_AURKA_ST	O14965	AURKA	O14965	AURKA	S104	S98R	98	Missense	distal	-6	no	48.023	49.052	EPSD;PhosphoSitePlus	COSMIC	39.062	Up-regulation
Other_Aur_AURKA_ST	O14965	AURKA	O14965	AURKA	S104	Q100L	100	Missense	distal	-4	no	48.023	47.905	EPSD;PhosphoSitePlus	COSMIC	39.062	Down-regulation
Other_Aur_AURKA_ST	O14965	AURKA	O14965	AURKA	S104	P106L	106	Missense	proximal	2	no	48.023	48.292	EPSD;PhosphoSitePlus	COSMIC	39.062	Up-regulation
Other_Aur_AURKA_ST	O14965	AURKA	O14965	AURKA	S104	E107D	107	Missense	distal	3	no	48.023	49.067	EPSD;PhosphoSitePlus	COSMIC	39.062	Up-regulation
Other_Aur_AURKA_ST	O14965	AURKA	O14965	AURKA	S226	R220G	220	Missense	distal	-6	no	43.359	39.569	EPSD;PhosphoSitePlus	COSMIC	39.062	Down-regulation
Other_Aur_AURKA_ST	O14965	AURKA	O14965	AURKA	S226	L222P	222	Missense	distal	-4	no	43.359	42.208	EPSD;PhosphoSitePlus	COSMIC;GDSC;CCLE	39.062	Down-regulation
Other_Aur_AURKA_ST	O14965	AURKA	O14965	AURKA	S266	A267V	267	Missense	proximal	1	no	46.555	46.375	EPSD;PhosphoSitePlus	COSMIC	39.062	Down-regulation
Other_Aur_AURKA_ST	O14965	AURKA	O14965	AURKA	S278	W277L	277	Missense	proximal	-1	no	45.129	39.895	EPSD;PhosphoSitePlus	COSMIC	39.062	Down-regulation
Other_Aur_AURKA_ST	O14965	AURKA	O14965	AURKA	S278	R285M	285	Missense	distal	7	no	45.129	45.105	EPSD;PhosphoSitePlus	COSMIC	39.062	Down-regulation
Other_Aur_AURKA_ST	O14965	AURKA	O14965	AURKA	S278	V279L	279	Missense	proximal	1	no	45.129	46.038	EPSD;PhosphoSitePlus	COSMIC	39.062	Up-regulation
Other_Aur_AURKA_ST	O14965	AURKA	O14965	AURKA	S278	V279A	279	Missense	proximal	1	no	45.129	45.309	EPSD;PhosphoSitePlus	COSMIC	39.062	Up-regulation
Other_Aur_AURKA_ST	O14965	AURKA	O14965	AURKA	T287	R285M	285	Missense	proximal	-2	no	51.557	33.726	EPSD;PhosphoSitePlus	COSMIC	39.062	Loss
Other_Aur_AURKA_ST	O14965	AURKA	O14965	AURKA	T287	G291D	291	Missense	distal	4	no	51.557	51.486	EPSD;PhosphoSitePlus	COSMIC	39.062	Down-regulation
Other_Aur_AURKA_ST	O14965	AURKA	O14965	AURKA	T287	T287I	287	Missense	central	0	yes	51.557	0.000	EPSD;PhosphoSitePlus	COSMIC	39.062	Loss
Other_Aur_AURKA_ST	O14965	AURKA	O14965	AURKA	T287	T287A	287	Missense	central	0	yes	51.557	0.000	EPSD;PhosphoSitePlus	COSMIC	39.062	Loss
Other_Aur_AURKA_ST	O14965	AURKA	O14965	AURKA	T287	C290F	290	Missense	distal	3	no	51.557	53.949	EPSD;PhosphoSitePlus	COSMIC	39.062	Up-regulation
Other_Aur_AURKA_ST	O14965	AURKA	O14965	AURKA	T288	R285M	285	Missense	distal	-3	no	63.877	50.979	EPSD;PhosphoSitePlus	COSMIC	39.062	Down-regulation
Other_Aur_AURKA_ST	O14965	AURKA	O14965	AURKA	T288	G291D	291	Missense	distal	3	no	63.877	65.038	EPSD;PhosphoSitePlus	COSMIC	39.062	Up-regulation
Other_Aur_AURKA_ST	O14965	AURKA	O14965	AURKA	T288	T287I	287	Missense	proximal	-1	no	63.877	63.668	EPSD;PhosphoSitePlus	COSMIC	39.062	Down-regulation
Other_Aur_AURKA_ST	O14965	AURKA	O14965	AURKA	T288	T287A	287	Missense	proximal	-1	no	63.877	62.287	EPSD;PhosphoSitePlus	COSMIC	39.062	Down-regulation
Other_Aur_AURKA_ST	O14965	AURKA	O14965	AURKA	T288	C290F	290	Missense	proximal	2	no	63.877	61.233	EPSD;PhosphoSitePlus	COSMIC	39.062	Down-regulation
Other_Aur_AURKA_ST	Q14980	NUMA1	O14965	AURKA	S83	L88Q	88	Missense	distal	5	no	44.362	46.835	EPSD	COSMIC	39.062	Up-regulation
Other_Aur_AURKA_ST	Q14980	NUMA1	O14965	AURKA	S83	P78S	78	Missense	distal	-5	no	44.362	44.383	EPSD	COSMIC	39.062	Up-regulation
Other_Aur_AURKA_ST	Q14980	NUMA1	O14965	AURKA	S83	P78L	78	Missense	distal	-5	no	44.362	44.375	EPSD	COSMIC	39.062	Up-regulation
Other_Aur_AURKA_ST	Q14980	NUMA1	O14965	AURKA	S83	L81Q	81	Missense	proximal	-2	no	44.362	43.444	EPSD	COSMIC	39.062	Down-regulation
Other_Aur_AURKA_ST	Q14980	NUMA1	O14965	AURKA	S271	K276R	276	Missense	distal	5	no	41.767	40.081	EPSD	COSMIC	39.062	Down-regulation
Other_Aur_AURKA_ST	Q14980	NUMA1	O14965	AURKA	S717	R723H	723	Missense	distal	6	no	39.501	39.504	EPSD	COSMIC	39.062	Up-regulation
Other_Aur_AURKA_ST	Q14980	NUMA1	O14965	AURKA	S1760	P1758H	1758	Missense	proximal	-2	no	38.560	46.381	EPSD	COSMIC	39.062	Gain
Other_Aur_AURKA_ST	Q14980	NUMA1	O14965	AURKA	S1772	K1766T	1766	Missense	distal	-6	no	49.153	51.103	EPSD	COSMIC	39.062	Up-regulation
Other_Aur_AURKA_ST	Q14980	NUMA1	O14965	AURKA	S1772	P1777L	1777	Missense	distal	5	no	49.153	48.569	EPSD	COSMIC	39.062	Down-regulation
Other_Aur_AURKA_ST	Q14980	NUMA1	O14965	AURKA	S1772	P1765L	1765	Missense	distal	-7	no	49.153	47.480	EPSD	COSMIC	39.062	Down-regulation
Other_Aur_AURKA_ST	Q14980	NUMA1	O14965	AURKA	S1772	T1776S	1776	Missense	distal	4	no	49.153	50.168	EPSD	COSMIC	39.062	Up-regulation
Other_Aur_AURKA_ST	Q14980	NUMA1	O14965	AURKA	T1804	S1800W	1800	Missense	distal	-4	no	44.896	36.191	EPSD;PhosphoSitePlus	COSMIC	39.062	Loss
Other_Aur_AURKA_ST	Q14980	NUMA1	O14965	AURKA	T1804	R1802H	1802	Missense	proximal	-2	no	44.896	37.658	EPSD;PhosphoSitePlus	COSMIC	39.062	Loss
Other_Aur_AURKA_ST	Q14980	NUMA1	O14965	AURKA	T1804	L1798P	1798	Missense	distal	-6	no	44.896	45.877	EPSD;PhosphoSitePlus	COSMIC	39.062	Up-regulation
Other_Aur_AURKA_ST	Q14980	NUMA1	O14965	AURKA	T1804	F1797L	1797	Missense	distal	-7	no	44.896	45.252	EPSD;PhosphoSitePlus	COSMIC	39.062	Up-regulation
Other_Aur_AURKA_ST	Q14980	NUMA1	O14965	AURKA	T1804	R1808C	1808	Missense	distal	4	no	44.896	44.870	EPSD;PhosphoSitePlus	COSMIC	39.062	Down-regulation
Other_Aur_AURKA_ST	Q14980	NUMA1	O14965	AURKA	T1804	S1800L	1800	Missense	distal	-4	no	44.896	44.131	EPSD;PhosphoSitePlus	COSMIC	39.062	Down-regulation
Other_Aur_AURKA_ST	Q14980	NUMA1	O14965	AURKA	T1804	R1802C	1802	Missense	proximal	-2	no	44.896	29.599	EPSD;PhosphoSitePlus	COSMIC;GDSC	39.062	Loss
Other_Aur_AURKA_ST	Q14980	NUMA1	O14965	AURKA	T1811	R1808C	1808	Missense	distal	-3	no	53.552	49.015	EPSD;PhosphoSitePlus	COSMIC	39.062	Down-regulation
Other_Aur_AURKA_ST	Q14980	NUMA1	O14965	AURKA	T1812	R1808C	1808	Missense	distal	-4	no	57.388	54.187	EPSD;PhosphoSitePlus	COSMIC	39.062	Down-regulation
Other_Aur_AURKA_ST	Q14980	NUMA1	O14965	AURKA	S1830	S1834L	1834	Missense	distal	4	no	41.852	41.946	EPSD	COSMIC	39.062	Up-regulation
Other_Aur_AURKA_ST	Q14980	NUMA1	O14965	AURKA	S1830	Y1836C	1836	Missense	distal	6	no	41.852	41.733	EPSD	COSMIC	39.062	Down-regulation
Other_Aur_AURKA_ST	Q14980	NUMA1	O14965	AURKA	S1830	Y1836H	1836	Missense	distal	6	no	41.852	41.908	EPSD	COSMIC	39.062	Up-regulation
Other_Aur_AURKA_ST	Q14980	NUMA1	O14965	AURKA	S1847	T1851A	1851	Missense	distal	4	no	38.139	39.187	EPSD	COSMIC;GDSC;CCLE	39.062	Gain
Other_Aur_AURKA_ST	Q14980	NUMA1	O14965	AURKA	T1851	S1856R	1856	Missense	distal	5	no	41.206	40.054	EPSD	COSMIC	39.062	Down-regulation
Other_Aur_AURKA_ST	Q14980	NUMA1	O14965	AURKA	T1851	L1857V	1857	Missense	distal	6	no	41.206	41.181	EPSD	COSMIC	39.062	Down-regulation
Other_Aur_AURKA_ST	Q14980	NUMA1	O14965	AURKA	T1851	T1851A	1851	Missense	central	0	yes	41.206	0.000	EPSD	COSMIC;GDSC;CCLE	39.062	Loss
Other_Aur_AURKA_ST	Q14980	NUMA1	O14965	AURKA	S1853	T1851A	1851	Missense	proximal	-2	no	38.087	45.662	EPSD	COSMIC;GDSC;CCLE	39.062	Gain
Other_Aur_AURKA_ST	Q14980	NUMA1	O14965	AURKA	T1879	R1881C	1881	Missense	proximal	2	no	45.315	48.469	EPSD	COSMIC	39.062	Up-regulation
Other_Aur_AURKA_ST	Q14980	NUMA1	O14965	AURKA	T1879	R1885H	1885	Missense	distal	6	no	45.315	45.319	EPSD	COSMIC	39.062	Up-regulation
Other_Aur_AURKA_ST	Q14980	NUMA1	O14965	AURKA	T1879	R1877C	1877	Missense	proximal	-2	no	45.315	30.018	EPSD	COSMIC	39.062	Loss
Other_Aur_AURKA_ST	Q14980	NUMA1	O14965	AURKA	T1879	S1872R	1872	Missense	distal	-7	no	45.315	45.889	EPSD	COSMIC	39.062	Up-regulation
Other_Aur_AURKA_ST	Q14980	NUMA1	O14965	AURKA	S1883	R1881C	1881	Missense	proximal	-2	no	42.852	27.554	EPSD	COSMIC	39.062	Loss
Other_Aur_AURKA_ST	Q14980	NUMA1	O14965	AURKA	S1883	R1885H	1885	Missense	proximal	2	no	42.852	41.747	EPSD	COSMIC	39.062	Down-regulation
Other_Aur_AURKA_ST	Q14980	NUMA1	O14965	AURKA	S1883	Q1888H	1888	Missense	distal	5	no	42.852	40.980	EPSD	COSMIC	39.062	Down-regulation
Other_Aur_AURKA_ST	Q14980	NUMA1	O14965	AURKA	S1883	R1877C	1877	Missense	distal	-6	no	42.852	35.804	EPSD	COSMIC	39.062	Loss
Other_Aur_AURKA_ST	Q14980	NUMA1	O14965	AURKA	S1887	R1881C	1881	Missense	distal	-6	no	54.760	47.712	PhosphoSitePlus;EPSD	COSMIC	39.062	Down-regulation
Other_Aur_AURKA_ST	Q14980	NUMA1	O14965	AURKA	S1887	R1885H	1885	Missense	proximal	-2	no	54.760	47.521	PhosphoSitePlus;EPSD	COSMIC	39.062	Down-regulation
Other_Aur_AURKA_ST	Q14980	NUMA1	O14965	AURKA	S1887	Q1888H	1888	Missense	proximal	1	no	54.760	51.881	PhosphoSitePlus;EPSD	COSMIC	39.062	Down-regulation
Other_Aur_AURKA_ST	Q14980	NUMA1	O14965	AURKA	S1901	P1897T	1897	Missense	distal	-4	no	48.810	52.724	EPSD	COSMIC	39.062	Up-regulation
Other_Aur_AURKA_ST	Q14980	NUMA1	O14965	AURKA	S1901	M1904I	1904	Missense	distal	3	no	48.810	49.364	EPSD	COSMIC	39.062	Up-regulation
Other_Aur_AURKA_ST	Q14980	NUMA1	O14965	AURKA	S1942	S1945F	1945	Missense	distal	3	no	40.777	40.831	EPSD	COSMIC	39.062	Up-regulation
Other_Aur_AURKA_ST	Q14980	NUMA1	O14965	AURKA	S1945	S1945F	1945	Missense	central	0	yes	56.533	0.000	EPSD	COSMIC	39.062	Loss
Other_Aur_AURKA_ST	Q14980	NUMA1	O14965	AURKA	S1969	I1973M	1973	Missense	distal	4	no	47.323	47.615	EPSD;PhosphoSitePlus	COSMIC	39.062	Up-regulation
Other_Aur_AURKA_ST	Q14980	NUMA1	O14965	AURKA	S1991	R1984W	1984	Missense	distal	-7	no	67.005	63.705	EPSD;PhosphoSitePlus	COSMIC	39.062	Down-regulation
Other_Aur_AURKA_ST	Q14980	NUMA1	O14965	AURKA	S1991	R1989L	1989	Missense	proximal	-2	no	67.005	57.284	EPSD;PhosphoSitePlus	COSMIC	39.062	Down-regulation
Other_Aur_AURKA_ST	Q14980	NUMA1	O14965	AURKA	S1991	R1989Q	1989	Missense	proximal	-2	no	67.005	56.366	EPSD;PhosphoSitePlus	COSMIC	39.062	Down-regulation
Other_Aur_AURKA_ST	Q14980	NUMA1	O14965	AURKA	S1991	R1987C	1987	Missense	distal	-4	no	67.005	63.804	EPSD;PhosphoSitePlus	COSMIC	39.062	Down-regulation
Other_Aur_AURKA_ST	Q14980	NUMA1	O14965	AURKA	S1991	P1994L	1994	Missense	distal	3	no	67.005	66.541	EPSD;PhosphoSitePlus	COSMIC	39.062	Down-regulation
Other_Aur_AURKA_ST	Q14980	NUMA1	O14965	AURKA	S2026	R2023C	2023	Missense	distal	-3	no	40.380	35.843	EPSD	COSMIC	39.062	Loss
Other_Aur_AURKA_ST	Q14980	NUMA1	O14965	AURKA	S2026	E2029D	2029	Missense	distal	3	no	40.380	41.424	EPSD	COSMIC	39.062	Up-regulation
Other_Aur_AURKA_ST	Q14980	NUMA1	O14965	AURKA	S2026	A2030V	2030	Missense	distal	4	no	40.380	40.086	EPSD	COSMIC	39.062	Down-regulation
Other_Aur_AURKA_ST	Q14980	NUMA1	O14965	AURKA	S2026	T2028I	2028	Missense	proximal	2	no	40.380	42.737	EPSD	COSMIC	39.062	Up-regulation
Other_Aur_AURKA_ST	Q14980	NUMA1	O14965	AURKA	T2027	E2029D	2029	Missense	proximal	2	no	38.902	39.672	EPSD	COSMIC	39.062	Gain
Other_Aur_AURKA_ST	Q14980	NUMA1	O14965	AURKA	S2047	R2044W	2044	Missense	distal	-3	no	49.503	-29.669	EPSD;PhosphoSitePlus	COSMIC	39.062	Loss
Other_Aur_AURKA_ST	Q14980	NUMA1	O14965	AURKA	S2047	S2047L	2047	Missense	central	0	yes	49.503	0.000	EPSD;PhosphoSitePlus	COSMIC;GDSC	39.062	Loss
Other_Aur_AURKA_ST	Q14980	NUMA1	O14965	AURKA	S2062	R2065H	2065	Missense	distal	3	no	39.183	38.917	EPSD	COSMIC	39.062	Loss
Other_Aur_AURKA_ST	Q14980	NUMA1	O14965	AURKA	S2062	R2065C	2065	Missense	distal	3	no	39.183	37.910	EPSD	COSMIC	39.062	Loss
Other_Aur_AURKA_ST	Q14980	NUMA1	O14965	AURKA	S2062	K2057E	2057	Missense	distal	-5	no	39.183	39.201	EPSD	COSMIC;GDSC	39.062	Up-regulation
Other_Aur_AURKA_ST	Q14980	NUMA1	O14965	AURKA	S2062	S2062N	2062	Missense	central	0	yes	39.183	0.000	EPSD	COSMIC	39.062	Loss
Other_Aur_AURKA_ST	Q14980	NUMA1	O14965	AURKA	S2062	G2067E	2067	Missense	distal	5	no	39.183	39.089	EPSD	COSMIC	39.062	Down-regulation
Other_Aur_AURKA_ST	Q14980	NUMA1	O14965	AURKA	S2062	R2066Q	2066	Missense	distal	4	no	39.183	39.597	EPSD	COSMIC	39.062	Up-regulation
Other_Aur_AURKA_ST	Q14980	NUMA1	O14965	AURKA	S2062	R2065W	2065	Missense	distal	3	no	39.183	37.456	EPSD	COSMIC	39.062	Loss
Other_Aur_AURKA_ST	Q14980	NUMA1	O14965	AURKA	S2069	R2065H	2065	Missense	distal	-4	no	40.768	36.333	EPSD	COSMIC	39.062	Loss
Other_Aur_AURKA_ST	Q14980	NUMA1	O14965	AURKA	S2069	R2065C	2065	Missense	distal	-4	no	40.768	37.567	EPSD	COSMIC	39.062	Loss
Other_Aur_AURKA_ST	Q14980	NUMA1	O14965	AURKA	S2069	S2062N	2062	Missense	distal	-7	no	40.768	40.104	EPSD	COSMIC	39.062	Down-regulation
Other_Aur_AURKA_ST	Q14980	NUMA1	O14965	AURKA	S2069	G2067E	2067	Missense	proximal	-2	no	40.768	30.265	EPSD	COSMIC	39.062	Loss
Other_Aur_AURKA_ST	Q14980	NUMA1	O14965	AURKA	S2069	A2072V	2072	Missense	distal	3	no	40.768	40.646	EPSD	COSMIC	39.062	Down-regulation
Other_Aur_AURKA_ST	Q14980	NUMA1	O14965	AURKA	S2069	R2066Q	2066	Missense	distal	-3	no	40.768	31.104	EPSD	COSMIC	39.062	Loss
Other_Aur_AURKA_ST	Q14980	NUMA1	O14965	AURKA	S2069	R2065W	2065	Missense	distal	-4	no	40.768	32.864	EPSD	COSMIC	39.062	Loss
Other_Aur_AURKA_ST	Q14980	NUMA1	O14965	AURKA	S2077	P2078L	2078	Missense	proximal	1	no	35.756	40.406	EPSD	COSMIC	39.062	Gain
Other_Aur_AURKA_ST	Q14980	NUMA1	O14965	AURKA	T2080	R2081H	2081	Missense	proximal	1	no	40.306	38.318	EPSD	COSMIC	39.062	Loss
Other_Aur_AURKA_ST	Q14980	NUMA1	O14965	AURKA	T2080	P2078L	2078	Missense	proximal	-2	no	40.306	45.645	EPSD	COSMIC	39.062	Up-regulation
Other_Aur_AURKA_ST	Q14980	NUMA1	O14965	AURKA	T2080	T2084P	2084	Missense	distal	4	no	40.306	41.268	EPSD	COSMIC;GDSC	39.062	Up-regulation
Other_Aur_AURKA_ST	Q14980	NUMA1	O14965	AURKA	T2080	T2080P	2080	Missense	central	0	yes	40.306	0.000	EPSD	COSMIC;GDSC	39.062	Loss
Other_Aur_AURKA_ST	Q14980	NUMA1	O14965	AURKA	T2080	R2086H	2086	Missense	distal	6	no	40.306	40.310	EPSD	COSMIC	39.062	Up-regulation
Other_Aur_AURKA_ST	Q14980	NUMA1	O14965	AURKA	T2080	R2085C	2085	Missense	distal	5	no	40.306	42.456	EPSD	COSMIC	39.062	Up-regulation
Other_Aur_AURKA_ST	Q14980	NUMA1	O14965	AURKA	T2084	A2091V	2091	Missense	distal	7	no	43.308	43.436	EPSD;PhosphoSitePlus	COSMIC	39.062	Up-regulation
Other_Aur_AURKA_ST	Q14980	NUMA1	O14965	AURKA	T2084	R2081H	2081	Missense	distal	-3	no	43.308	37.535	EPSD;PhosphoSitePlus	COSMIC	39.062	Loss
Other_Aur_AURKA_ST	Q14980	NUMA1	O14965	AURKA	T2084	P2078L	2078	Missense	distal	-6	no	43.308	42.327	EPSD;PhosphoSitePlus	COSMIC	39.062	Down-regulation
Other_Aur_AURKA_ST	Q14980	NUMA1	O14965	AURKA	T2084	T2084P	2084	Missense	central	0	yes	43.308	0.000	EPSD;PhosphoSitePlus	COSMIC;GDSC	39.062	Loss
Other_Aur_AURKA_ST	Q14980	NUMA1	O14965	AURKA	T2084	T2080P	2080	Missense	distal	-4	no	43.308	39.394	EPSD;PhosphoSitePlus	COSMIC;GDSC	39.062	Down-regulation
Other_Aur_AURKA_ST	Q14980	NUMA1	O14965	AURKA	T2084	P2088L	2088	Missense	distal	4	no	43.308	43.455	EPSD;PhosphoSitePlus	COSMIC	39.062	Up-regulation
Other_Aur_AURKA_ST	Q14980	NUMA1	O14965	AURKA	T2084	R2086H	2086	Missense	proximal	2	no	43.308	42.204	EPSD;PhosphoSitePlus	COSMIC	39.062	Down-regulation
Other_Aur_AURKA_ST	Q14980	NUMA1	O14965	AURKA	T2084	R2085C	2085	Missense	proximal	1	no	43.308	38.174	EPSD;PhosphoSitePlus	COSMIC	39.062	Loss
Other_Aur_AURKA_ST	Q14980	NUMA1	O14965	AURKA	T2084	A2091T	2091	Missense	distal	7	no	43.308	43.298	EPSD;PhosphoSitePlus	COSMIC	39.062	Down-regulation
Other_Aur_AURKA_ST	Q14980	NUMA1	O14965	AURKA	S2087	P2088L	2088	Missense	proximal	1	no	35.424	40.074	EPSD;PhosphoSitePlus	COSMIC	39.062	Gain
Other_Aur_AURKA_ST	Q96EZ8	MCRS1	O14965	AURKA	S36	P43L	43	Missense	distal	7	no	46.092	46.175	PhosphoSitePlus;EPSD	COSMIC	39.062	Up-regulation
Other_Aur_AURKA_ST	Q96EZ8	MCRS1	O14965	AURKA	S47	S48F	48	Missense	proximal	1	no	35.419	41.899	EPSD	COSMIC	39.062	Gain
Other_Aur_AURKA_ST	Q96EZ8	MCRS1	O14965	AURKA	S48	R50M	50	Missense	proximal	2	no	39.106	39.568	EPSD	COSMIC	39.062	Up-regulation
Other_Aur_AURKA_ST	Q96EZ8	MCRS1	O14965	AURKA	S48	R45Q	45	Missense	distal	-3	no	39.106	29.442	EPSD	COSMIC	39.062	Loss
Other_Aur_AURKA_ST	Q96EZ8	MCRS1	O14965	AURKA	S48	S48F	48	Missense	central	0	yes	39.106	0.000	EPSD	COSMIC	39.062	Loss
Other_Aur_AURKA_ST	Q96EZ8	MCRS1	O14965	AURKA	S48	K53R	53	Missense	distal	5	no	39.106	37.419	EPSD	COSMIC	39.062	Loss
Other_Aur_AURKA_ST	Q96EZ8	MCRS1	O14965	AURKA	S48	P43L	43	Missense	distal	-5	no	39.106	39.118	EPSD	COSMIC	39.062	Up-regulation
Other_Aur_AURKA_ST	Q96EZ8	MCRS1	O14965	AURKA	S48	K53M	53	Missense	distal	5	no	39.106	36.744	EPSD	COSMIC	39.062	Loss
Other_Aur_AURKA_ST	Q96EZ8	MCRS1	O14965	AURKA	S48	R50G	50	Missense	proximal	2	no	39.106	40.477	EPSD	COSMIC	39.062	Up-regulation
Other_Aur_AURKA_ST	Q96EZ8	MCRS1	O14965	AURKA	S85	S90F	90	Missense	distal	5	no	38.823	39.534	EPSD	COSMIC	39.062	Gain
Other_Aur_AURKA_ST	Q96EZ8	MCRS1	O14965	AURKA	S102	T103A	103	Missense	proximal	1	no	38.382	40.054	EPSD	COSMIC	39.062	Gain
Other_Aur_AURKA_ST	Q96EZ8	MCRS1	O14965	AURKA	T167	V160M	160	Missense	distal	-7	no	45.075	45.377	EPSD	COSMIC	39.062	Up-regulation
Other_Aur_AURKA_ST	Q96EZ8	MCRS1	O14965	AURKA	T167	R174C	174	Missense	distal	7	no	45.075	45.116	EPSD	COSMIC	39.062	Up-regulation
Other_Aur_AURKA_ST	Q96EZ8	MCRS1	O14965	AURKA	T167	T167I	167	Missense	central	0	yes	45.075	0.000	EPSD	COSMIC	39.062	Loss
Other_Aur_AURKA_ST	Q96EZ8	MCRS1	O14965	AURKA	S218	K219T	219	Missense	proximal	1	no	39.919	39.283	EPSD	COSMIC	39.062	Down-regulation
Other_Aur_AURKA_ST	Q96EZ8	MCRS1	O14965	AURKA	S218	E213K	213	Missense	distal	-5	no	39.919	39.901	EPSD	COSMIC	39.062	Down-regulation
Other_Aur_AURKA_ST	Q96R06	SPAG5	O14965	AURKA	S183	G179E	179	Missense	distal	-4	no	42.865	44.701	EPSD	COSMIC	39.062	Up-regulation
Other_Aur_AURKA_ST	Q96R06	SPAG5	O14965	AURKA	S183	A187T	187	Missense	distal	4	no	42.865	41.817	EPSD	COSMIC	39.062	Down-regulation
Other_Aur_AURKA_ST	Q96R06	SPAG5	O14965	AURKA	S183	A186S	186	Missense	distal	3	no	42.865	44.320	EPSD	COSMIC	39.062	Up-regulation
Other_Aur_AURKA_ST	Q96R06	SPAG5	O14965	AURKA	S334	G333V	333	Missense	proximal	-1	no	39.101	37.883	EPSD	COSMIC	39.062	Loss
Other_Aur_AURKA_ST	Q96R06	SPAG5	O14965	AURKA	S334	D335N	335	Missense	proximal	1	no	39.101	33.526	EPSD	COSMIC	39.062	Loss
Other_Aur_AURKA_ST	Q96R06	SPAG5	O14965	AURKA	S362	M355V	355	Missense	distal	-7	no	40.293	39.992	EPSD	COSMIC	39.062	Down-regulation
Other_Aur_AURKA_ST	Q96R06	SPAG5	O14965	AURKA	S362	L369F	369	Missense	distal	7	no	40.293	40.342	EPSD	COSMIC	39.062	Up-regulation
Other_Aur_AURKA_ST	Q96R06	SPAG5	O14965	AURKA	S364	L369F	369	Missense	distal	5	no	38.005	39.962	EPSD	COSMIC	39.062	Gain
Other_Aur_AURKA_ST	Q96R06	SPAG5	O14965	AURKA	S367	R370W	370	Missense	distal	3	no	44.908	43.182	EPSD	COSMIC	39.062	Down-regulation
Other_Aur_AURKA_ST	Q96R06	SPAG5	O14965	AURKA	S367	L369F	369	Missense	proximal	2	no	44.908	45.191	EPSD	COSMIC	39.062	Up-regulation
Other_Aur_AURKA_ST	Q96R06	SPAG5	O14965	AURKA	S401	G407D	407	Missense	distal	6	no	45.115	45.265	EPSD	COSMIC	39.062	Up-regulation
Other_Aur_AURKA_ST	Q96R06	SPAG5	O14965	AURKA	S401	E395K	395	Missense	distal	-6	no	45.115	46.298	EPSD	COSMIC	39.062	Up-regulation
Other_Aur_AURKA_ST	Q96R06	SPAG5	O14965	AURKA	S449	E446V	446	Missense	distal	-3	no	37.370	41.573	EPSD	COSMIC	39.062	Gain
Other_Aur_AURKA_ST	Q96R06	SPAG5	O14965	AURKA	S1062	I1059V	1059	Missense	distal	-3	no	36.639	39.747	EPSD	COSMIC	39.062	Gain
Other_Aur_AURKA_ST	Q14203	DCTN1	O14965	AURKA	S92	Q95H	95	Missense	distal	3	no	43.751	43.097	EPSD	COSMIC	39.062	Down-regulation
Other_Aur_AURKA_ST	Q14203	DCTN1	O14965	AURKA	S92	E98K	98	Missense	distal	6	no	43.751	43.585	EPSD	COSMIC	39.062	Down-regulation
Other_Aur_AURKA_ST	Q14203	DCTN1	O14965	AURKA	S112	D110N	110	Missense	proximal	-2	no	40.931	39.112	EPSD	COSMIC	39.062	Down-regulation
Other_Aur_AURKA_ST	Q14203	DCTN1	O14965	AURKA	S112	S112R	112	Missense	central	0	yes	40.931	0.000	EPSD	COSMIC	39.062	Loss
Other_Aur_AURKA_ST	Q14203	DCTN1	O14965	AURKA	S112	T108I	108	Missense	distal	-4	no	40.931	33.225	EPSD	COSMIC	39.062	Loss
Other_Aur_AURKA_ST	Q14203	DCTN1	O14965	AURKA	S114	S112R	112	Missense	proximal	-2	no	33.916	47.074	EPSD	COSMIC	39.062	Gain
Other_Aur_AURKA_ST	Q14203	DCTN1	O14965	AURKA	T145	T146K	146	Missense	proximal	1	no	39.286	39.923	EPSD	COSMIC	39.062	Up-regulation
Other_Aur_AURKA_ST	Q14203	DCTN1	O14965	AURKA	T145	P152L	152	Missense	distal	7	no	39.286	39.369	EPSD	COSMIC	39.062	Up-regulation
Other_Aur_AURKA_ST	Q14203	DCTN1	O14965	AURKA	T145	P140L	140	Missense	distal	-5	no	39.286	39.299	EPSD	COSMIC	39.062	Up-regulation
Other_Aur_AURKA_ST	Q14203	DCTN1	O14965	AURKA	T145	P140Q	140	Missense	distal	-5	no	39.286	39.301	EPSD	COSMIC	39.062	Up-regulation
Other_Aur_AURKA_ST	Q14203	DCTN1	O14965	AURKA	T145	R148Q	148	Missense	distal	3	no	39.286	39.675	EPSD	COSMIC	39.062	Up-regulation
Other_Aur_AURKA_ST	Q14203	DCTN1	O14965	AURKA	T145	T147A	147	Missense	proximal	2	no	39.286	40.546	EPSD	COSMIC;GDSC;CCLE	39.062	Up-regulation
Other_Aur_AURKA_ST	Q14203	DCTN1	O14965	AURKA	T146	T146K	146	Missense	central	0	yes	57.314	0.000	EPSD	COSMIC	39.062	Loss
Other_Aur_AURKA_ST	Q14203	DCTN1	O14965	AURKA	T146	P152L	152	Missense	distal	6	no	57.314	57.307	EPSD	COSMIC	39.062	Down-regulation
Other_Aur_AURKA_ST	Q14203	DCTN1	O14965	AURKA	T146	P140L	140	Missense	distal	-6	no	57.314	56.333	EPSD	COSMIC	39.062	Down-regulation
Other_Aur_AURKA_ST	Q14203	DCTN1	O14965	AURKA	T146	P140Q	140	Missense	distal	-6	no	57.314	58.027	EPSD	COSMIC	39.062	Up-regulation
Other_Aur_AURKA_ST	Q14203	DCTN1	O14965	AURKA	T146	R148Q	148	Missense	proximal	2	no	57.314	59.315	EPSD	COSMIC	39.062	Up-regulation
Other_Aur_AURKA_ST	Q14203	DCTN1	O14965	AURKA	T146	T145S	145	Missense	proximal	-1	no	57.314	55.612	EPSD	COSMIC	39.062	Down-regulation
Other_Aur_AURKA_ST	Q14203	DCTN1	O14965	AURKA	T146	T147A	147	Missense	proximal	1	no	57.314	58.986	EPSD	COSMIC;GDSC;CCLE	39.062	Up-regulation
Other_Aur_AURKA_ST	Q14203	DCTN1	O14965	AURKA	T146	T153K	153	Missense	distal	7	no	57.314	57.316	EPSD	COSMIC	39.062	Up-regulation
Other_Aur_AURKA_ST	Q14203	DCTN1	O14965	AURKA	T147	T145S	145	Missense	proximal	-2	no	35.370	41.425	EPSD	COSMIC	39.062	Gain
Other_Aur_AURKA_ST	Q14203	DCTN1	O14965	AURKA	S172	P169T	169	Missense	distal	-3	no	39.383	38.426	EPSD	COSMIC	39.062	Loss
Other_Aur_AURKA_ST	Q14203	DCTN1	O14965	AURKA	S172	G176V	176	Missense	distal	4	no	39.383	38.845	EPSD	COSMIC	39.062	Loss
Other_Aur_AURKA_ST	Q14203	DCTN1	O14965	AURKA	S172	A173V	173	Missense	proximal	1	no	39.383	39.203	EPSD	COSMIC	39.062	Down-regulation
Other_Aur_AURKA_ST	Q14203	DCTN1	O14965	AURKA	S203	V200F	200	Missense	distal	-3	no	44.393	37.460	EPSD	COSMIC	39.062	Loss
Other_Aur_AURKA_ST	Q14203	DCTN1	O14965	AURKA	S203	V207G	207	Missense	distal	4	no	44.393	44.931	EPSD	COSMIC	39.062	Up-regulation
Other_Aur_AURKA_ST	Q14203	DCTN1	O14965	AURKA	S203	V207F	207	Missense	distal	4	no	44.393	45.136	EPSD	COSMIC	39.062	Up-regulation
Other_Aur_AURKA_ST	Q14203	DCTN1	O14965	AURKA	S351	A354T	354	Missense	distal	3	no	40.649	39.517	EPSD	COSMIC	39.062	Down-regulation
Other_Aur_AURKA_ST	Q14203	DCTN1	O14965	AURKA	S351	A355T	355	Missense	distal	4	no	40.649	39.601	EPSD	COSMIC	39.062	Down-regulation
Other_Aur_AURKA_ST	Q14203	DCTN1	O14965	AURKA	S351	E345K	345	Missense	distal	-6	no	40.649	41.832	EPSD	COSMIC	39.062	Up-regulation
Other_Aur_AURKA_ST	Q14203	DCTN1	O14965	AURKA	S351	D352N	352	Missense	proximal	1	no	40.649	35.075	EPSD	COSMIC	39.062	Loss
Other_Aur_AURKA_ST	Q14203	DCTN1	O14965	AURKA	S356	L360F	360	Missense	distal	4	no	39.897	40.286	EPSD	COSMIC	39.062	Up-regulation
Other_Aur_AURKA_ST	Q14203	DCTN1	O14965	AURKA	S356	L363F	363	Missense	distal	7	no	39.897	39.945	EPSD	COSMIC	39.062	Up-regulation
Other_Aur_AURKA_ST	Q14203	DCTN1	O14965	AURKA	S356	A354T	354	Missense	proximal	-2	no	39.897	32.321	EPSD	COSMIC	39.062	Loss
Other_Aur_AURKA_ST	Q14203	DCTN1	O14965	AURKA	S356	A355T	355	Missense	proximal	-1	no	39.897	41.486	EPSD	COSMIC	39.062	Up-regulation
Other_Aur_AURKA_ST	Q14203	DCTN1	O14965	AURKA	S356	D352N	352	Missense	distal	-4	no	39.897	43.953	EPSD	COSMIC	39.062	Up-regulation
Other_Aur_AURKA_ST	Q14203	DCTN1	O14965	AURKA	S356	K361M	361	Missense	distal	5	no	39.897	37.534	EPSD	COSMIC	39.062	Loss
Other_Aur_AURKA_ST	Q14203	DCTN1	O14965	AURKA	S417	E415G	415	Missense	proximal	-2	no	28.830	39.333	EPSD	COSMIC	39.062	Gain
Other_Aur_AURKA_ST	Q14203	DCTN1	O14965	AURKA	S417	E415K	415	Missense	proximal	-2	no	28.830	42.973	EPSD	COSMIC	39.062	Gain
Other_Aur_AURKA_ST	Q14203	DCTN1	O14965	AURKA	S586	Q580H	580	Missense	distal	-6	no	45.471	44.168	EPSD	COSMIC	39.062	Down-regulation
Other_Aur_AURKA_ST	Q14203	DCTN1	O14965	AURKA	S687	G686E	686	Missense	proximal	-1	no	40.526	39.687	EPSD	COSMIC	39.062	Down-regulation
Other_Aur_AURKA_ST	Q14203	DCTN1	O14965	AURKA	S687	L688V	688	Missense	proximal	1	no	40.526	39.616	EPSD	COSMIC	39.062	Down-regulation
Other_Aur_AURKA_ST	Q14203	DCTN1	O14965	AURKA	S687	E691Q	691	Missense	distal	4	no	40.526	39.948	EPSD	COSMIC;GDSC;CCLE	39.062	Down-regulation
Other_Aur_AURKA_ST	Q14203	DCTN1	O14965	AURKA	S687	A694G	694	Missense	distal	7	no	40.526	40.699	EPSD	COSMIC	39.062	Up-regulation
Other_Aur_AURKA_ST	Q14203	DCTN1	O14965	AURKA	S687	V685G	685	Missense	proximal	-2	no	40.526	41.422	EPSD	COSMIC;GDSC	39.062	Up-regulation
Other_Aur_AURKA_ST	Q14203	DCTN1	O14965	AURKA	S687	S687N	687	Missense	central	0	yes	40.526	0.000	EPSD	COSMIC	39.062	Loss
Other_Aur_AURKA_ST	Q14203	DCTN1	O14965	AURKA	S687	G686D	686	Missense	proximal	-1	no	40.526	41.788	EPSD	COSMIC	39.062	Up-regulation
Other_Aur_AURKA_ST	Q14203	DCTN1	O14965	AURKA	S687	A694V	694	Missense	distal	7	no	40.526	40.653	EPSD	COSMIC	39.062	Up-regulation
Other_Aur_AURKA_ST	Q14203	DCTN1	O14965	AURKA	S974	R972P	972	Missense	proximal	-2	no	45.307	30.248	EPSD	COSMIC	39.062	Loss
Other_Aur_AURKA_ST	Q14203	DCTN1	O14965	AURKA	S974	A969V	969	Missense	distal	-5	no	45.307	45.333	EPSD	COSMIC	39.062	Up-regulation
Other_Aur_AURKA_ST	Q14203	DCTN1	O14965	AURKA	S1090	I1097S	1097	Missense	distal	7	no	42.568	42.456	EPSD	COSMIC	39.062	Down-regulation
Other_Aur_AURKA_ST	Q14203	DCTN1	O14965	AURKA	T1152	Q1154E	1154	Missense	proximal	2	no	43.089	42.750	EPSD	COSMIC	39.062	Down-regulation
Other_Aur_AURKA_ST	Q14203	DCTN1	O14965	AURKA	T1152	L1159S	1159	Missense	distal	7	no	43.089	43.116	EPSD	COSMIC	39.062	Up-regulation
Other_Aur_AURKA_ST	Q14203	DCTN1	O14965	AURKA	S1153	Q1154E	1154	Missense	proximal	1	no	56.697	54.447	EPSD	COSMIC	39.062	Down-regulation
Other_Aur_AURKA_ST	Q14203	DCTN1	O14965	AURKA	S1153	L1159S	1159	Missense	distal	6	no	56.697	56.760	EPSD	COSMIC	39.062	Up-regulation
Other_Aur_AURKA_ST	Q14203	DCTN1	O14965	AURKA	T1158	Q1154E	1154	Missense	distal	-4	no	38.603	39.967	EPSD	COSMIC	39.062	Gain
Other_Aur_AURKA_ST	Q13761	RUNX3	O14965	AURKA	S149	K148N	148	Missense	proximal	-1	no	43.524	42.043	EPSD	COSMIC	39.062	Down-regulation
Other_Aur_AURKA_ST	Q13761	RUNX3	O14965	AURKA	S149	R146P	146	Missense	distal	-3	no	43.524	34.865	EPSD	COSMIC	39.062	Loss
Other_Aur_AURKA_ST	Q13761	RUNX3	O14965	AURKA	S149	R143L	143	Missense	distal	-6	no	43.524	40.963	EPSD	COSMIC	39.062	Down-regulation
Other_Aur_AURKA_ST	Q13761	RUNX3	O14965	AURKA	S149	R143H	143	Missense	distal	-6	no	43.524	41.354	EPSD	COSMIC	39.062	Down-regulation
Other_Aur_AURKA_ST	Q13761	RUNX3	O14965	AURKA	S149	R143C	143	Missense	distal	-6	no	43.524	36.476	EPSD	COSMIC	39.062	Loss
Other_Aur_AURKA_ST	Q13761	RUNX3	O14965	AURKA	S149	L152M	152	Missense	distal	3	no	43.524	44.516	EPSD	COSMIC	39.062	Up-regulation
Other_Aur_AURKA_ST	Q13761	RUNX3	O14965	AURKA	S149	S144R	144	Missense	distal	-5	no	43.524	43.529	EPSD	COSMIC	39.062	Up-regulation
Other_Aur_AURKA_ST	Q13761	RUNX3	O14965	AURKA	T173	V174M	174	Missense	proximal	1	no	43.328	43.327	EPSD;PhosphoSitePlus	COSMIC	39.062	Down-regulation
Other_Aur_AURKA_ST	Q13761	RUNX3	O14965	AURKA	T173	K171N	171	Missense	proximal	-2	no	43.328	39.349	EPSD;PhosphoSitePlus	COSMIC	39.062	Down-regulation
Other_Aur_AURKA_ST	Q13761	RUNX3	O14965	AURKA	T173	R178L	178	Missense	distal	5	no	43.328	43.235	EPSD;PhosphoSitePlus	COSMIC	39.062	Down-regulation
Other_Aur_AURKA_ST	Q13761	RUNX3	O14965	AURKA	T173	R168L	168	Missense	distal	-5	no	43.328	43.315	EPSD;PhosphoSitePlus	COSMIC	39.062	Down-regulation
Other_Aur_AURKA_ST	Q13761	RUNX3	O14965	AURKA	T173	R178W	178	Missense	distal	5	no	43.328	44.327	EPSD;PhosphoSitePlus	COSMIC	39.062	Up-regulation
Other_Aur_AURKA_ST	Q13761	RUNX3	O14965	AURKA	T173	G176R	176	Missense	distal	3	no	43.328	42.669	EPSD;PhosphoSitePlus	COSMIC	39.062	Down-regulation
Other_Aur_AURKA_ST	Q13761	RUNX3	O14965	AURKA	T173	T173I	173	Missense	central	0	yes	43.328	0.000	EPSD;PhosphoSitePlus	COSMIC;CCLE	39.062	Loss
Other_Aur_AURKA_ST	Q13761	RUNX3	O14965	AURKA	T173	A169S	169	Missense	distal	-4	no	43.328	46.289	EPSD;PhosphoSitePlus	COSMIC	39.062	Up-regulation
Other_Aur_AURKA_ST	Q13761	RUNX3	O14965	AURKA	T173	V172L	172	Missense	proximal	-1	no	43.328	42.917	EPSD;PhosphoSitePlus	COSMIC	39.062	Down-regulation
Other_Aur_AURKA_ST	Q13761	RUNX3	O14965	AURKA	T173	R178Q	178	Missense	distal	5	no	43.328	45.708	EPSD;PhosphoSitePlus	COSMIC	39.062	Up-regulation
Other_Aur_AURKA_ST	Q13761	RUNX3	O14965	AURKA	T209	R205C	205	Missense	distal	-4	no	47.344	44.143	EPSD	COSMIC	39.062	Down-regulation
Other_Aur_AURKA_ST	Q13761	RUNX3	O14965	AURKA	T209	P210L	210	Missense	proximal	1	no	47.344	51.994	EPSD	COSMIC	39.062	Up-regulation
Other_Aur_AURKA_ST	Q13761	RUNX3	O14965	AURKA	T209	V208G	208	Missense	proximal	-1	no	47.344	48.561	EPSD	COSMIC	39.062	Up-regulation
Other_Aur_AURKA_ST	Q13761	RUNX3	O14965	AURKA	T209	R216Q	216	Missense	distal	7	no	47.344	47.287	EPSD	COSMIC	39.062	Down-regulation
Other_Aur_AURKA_ST	Q13761	RUNX3	O14965	AURKA	T209	R203L	203	Missense	distal	-6	no	47.344	44.783	EPSD	COSMIC	39.062	Down-regulation
Other_Aur_AURKA_ST	Q13761	RUNX3	O14965	AURKA	T209	S214G	214	Missense	distal	5	no	47.344	47.445	EPSD	COSMIC	39.062	Up-regulation
Other_Aur_AURKA_ST	Q13761	RUNX3	O14965	AURKA	T209	P215L	215	Missense	distal	6	no	47.344	47.337	EPSD	COSMIC	39.062	Down-regulation
Other_Aur_AURKA_ST	Q13761	RUNX3	O14965	AURKA	T209	R205H	205	Missense	distal	-4	no	47.344	42.909	EPSD	COSMIC	39.062	Down-regulation
Other_Aur_AURKA_ST	Q13761	RUNX3	O14965	AURKA	T212	P210L	210	Missense	proximal	-2	no	35.080	40.418	EPSD	COSMIC	39.062	Gain
Other_Aur_AURKA_ST	Q13761	RUNX3	O14965	AURKA	S218	S220G	220	Missense	proximal	2	no	46.876	47.042	EPSD	COSMIC	39.062	Up-regulation
Other_Aur_AURKA_ST	Q13761	RUNX3	O14965	AURKA	S218	S223R	223	Missense	distal	5	no	46.876	45.724	EPSD	COSMIC	39.062	Down-regulation
Other_Aur_AURKA_ST	Q13761	RUNX3	O14965	AURKA	S218	R216Q	216	Missense	proximal	-2	no	46.876	36.237	EPSD	COSMIC	39.062	Loss
Other_Aur_AURKA_ST	Q13761	RUNX3	O14965	AURKA	S218	S214G	214	Missense	distal	-4	no	46.876	45.757	EPSD	COSMIC	39.062	Down-regulation
Other_Aur_AURKA_ST	Q13761	RUNX3	O14965	AURKA	S218	S220N	220	Missense	proximal	2	no	46.876	46.311	EPSD	COSMIC	39.062	Down-regulation
Other_Aur_AURKA_ST	Q13761	RUNX3	O14965	AURKA	S218	P215L	215	Missense	distal	-3	no	46.876	48.020	EPSD	COSMIC	39.062	Up-regulation
Other_Aur_AURKA_ST	Q13761	RUNX3	O14965	AURKA	S220	S220G	220	Missense	central	0	yes	52.679	0.000	EPSD	COSMIC	39.062	Loss
Other_Aur_AURKA_ST	Q13761	RUNX3	O14965	AURKA	S220	S223R	223	Missense	distal	3	no	52.679	51.614	EPSD	COSMIC	39.062	Down-regulation
Other_Aur_AURKA_ST	Q13761	RUNX3	O14965	AURKA	S220	R216Q	216	Missense	distal	-4	no	52.679	52.833	EPSD	COSMIC	39.062	Up-regulation
Other_Aur_AURKA_ST	Q13761	RUNX3	O14965	AURKA	S220	S214G	214	Missense	distal	-6	no	52.679	49.918	EPSD	COSMIC	39.062	Down-regulation
Other_Aur_AURKA_ST	Q13761	RUNX3	O14965	AURKA	S220	S220N	220	Missense	central	0	yes	52.679	0.000	EPSD	COSMIC	39.062	Loss
Other_Aur_AURKA_ST	Q13761	RUNX3	O14965	AURKA	S220	P215L	215	Missense	distal	-5	no	52.679	52.692	EPSD	COSMIC	39.062	Up-regulation
Other_Aur_AURKA_ST	Q13761	RUNX3	O14965	AURKA	S226	P229L	229	Missense	distal	3	no	42.102	41.639	EPSD	COSMIC	39.062	Down-regulation
Other_Aur_AURKA_ST	Q13761	RUNX3	O14965	AURKA	S226	P232T	232	Missense	distal	6	no	42.102	42.062	EPSD	COSMIC	39.062	Down-regulation
Other_Aur_AURKA_ST	Q13761	RUNX3	O14965	AURKA	S226	S220G	220	Missense	distal	-6	no	42.102	39.341	EPSD	COSMIC	39.062	Down-regulation
Other_Aur_AURKA_ST	Q13761	RUNX3	O14965	AURKA	S226	S223R	223	Missense	distal	-3	no	42.102	48.582	EPSD	COSMIC	39.062	Up-regulation
Other_Aur_AURKA_ST	Q13761	RUNX3	O14965	AURKA	S226	Q230K	230	Missense	distal	4	no	42.102	42.664	EPSD	COSMIC	39.062	Up-regulation
Other_Aur_AURKA_ST	Q13761	RUNX3	O14965	AURKA	S226	P232Q	232	Missense	distal	6	no	42.102	42.097	EPSD	COSMIC	39.062	Down-regulation
Other_Aur_AURKA_ST	Q13761	RUNX3	O14965	AURKA	S226	S220N	220	Missense	distal	-6	no	42.102	45.307	EPSD	COSMIC	39.062	Up-regulation
Other_Aur_AURKA_ST	Q13761	RUNX3	O14965	AURKA	S226	P232S	232	Missense	distal	6	no	42.102	42.159	EPSD	COSMIC	39.062	Up-regulation
Other_Aur_AURKA_ST	Q13761	RUNX3	O14965	AURKA	S243	P241L	241	Missense	proximal	-2	no	38.377	43.715	EPSD	COSMIC	39.062	Gain
Other_Aur_AURKA_ST	Q13761	RUNX3	O14965	AURKA	S243	D244A	244	Missense	proximal	1	no	38.377	39.220	EPSD	COSMIC	39.062	Gain
Other_Aur_AURKA_ST	Q13761	RUNX3	O14965	AURKA	S301	P298S	298	Missense	distal	-3	no	38.261	40.441	EPSD	COSMIC	39.062	Gain
Other_Aur_AURKA_ST	Q13761	RUNX3	O14965	AURKA	S301	A299D	299	Missense	proximal	-2	no	38.261	41.237	EPSD	COSMIC	39.062	Gain
Other_Aur_AURKA_ST	Q13761	RUNX3	O14965	AURKA	S301	R302L	302	Missense	proximal	1	no	38.261	40.692	EPSD	COSMIC	39.062	Gain
Other_Aur_AURKA_ST	P00352	ALDH1A1	O14965	AURKA	S207	A206V	206	Missense	proximal	-1	no	53.109	51.838	EPSD	COSMIC	39.062	Down-regulation
Other_Aur_AURKA_ST	P00352	ALDH1A1	O14965	AURKA	S207	A212T	212	Missense	distal	5	no	53.109	53.740	EPSD	COSMIC	39.062	Up-regulation
Other_Aur_AURKA_ST	P46937	YAP1	O14965	AURKA	S61	E62D	62	Missense	proximal	1	no	41.251	43.468	EPSD	COSMIC	39.062	Up-regulation
Other_Aur_AURKA_ST	P46937	YAP1	O14965	AURKA	T77	V72G	72	Missense	distal	-5	no	41.891	41.880	EPSD	COSMIC	39.062	Down-regulation
Other_Aur_AURKA_ST	P46937	YAP1	O14965	AURKA	T77	M73I	73	Missense	distal	-4	no	41.891	37.004	EPSD	COSMIC	39.062	Loss
Other_Aur_AURKA_ST	P46937	YAP1	O14965	AURKA	S105	K102R	102	Missense	distal	-3	no	34.760	42.586	EPSD	COSMIC	39.062	Gain
Other_Aur_AURKA_ST	P46937	YAP1	O14965	AURKA	T110	R106G	106	Missense	distal	-4	no	39.541	39.222	EPSD	COSMIC	39.062	Down-regulation
Other_Aur_AURKA_ST	P46937	YAP1	O14965	AURKA	T110	S105P	105	Missense	distal	-5	no	39.541	39.520	EPSD	COSMIC	39.062	Down-regulation
Other_Aur_AURKA_ST	P46937	YAP1	O14965	AURKA	S127	A125G	125	Missense	proximal	-2	no	37.857	39.351	EPSD	COSMIC	39.062	Gain
Other_Aur_AURKA_ST	P46937	YAP1	O14965	AURKA	S128	L132R	132	Missense	distal	4	no	39.989	39.364	EPSD	COSMIC	39.062	Down-regulation
Other_Aur_AURKA_ST	P46937	YAP1	O14965	AURKA	S128	Q133H	133	Missense	distal	5	no	39.989	38.117	EPSD	COSMIC	39.062	Loss
Other_Aur_AURKA_ST	P46937	YAP1	O14965	AURKA	S128	S127F	127	Missense	proximal	-1	no	39.989	41.062	EPSD	COSMIC	39.062	Up-regulation
Other_Aur_AURKA_ST	P46937	YAP1	O14965	AURKA	S128	A125G	125	Missense	distal	-3	no	39.989	42.688	EPSD	COSMIC	39.062	Up-regulation
Other_Aur_AURKA_ST	P46937	YAP1	O14965	AURKA	S163	D170N	170	Missense	distal	7	no	46.607	46.457	EPSD	COSMIC	39.062	Down-regulation
Other_Aur_AURKA_ST	P46937	YAP1	O14965	AURKA	S163	I167T	167	Missense	distal	4	no	46.607	45.005	EPSD	COSMIC	39.062	Down-regulation
Other_Aur_AURKA_ST	P46937	YAP1	O14965	AURKA	S163	Q162R	162	Missense	proximal	-1	no	46.607	46.948	EPSD	COSMIC	39.062	Up-regulation
Other_Aur_AURKA_ST	P46937	YAP1	O14965	AURKA	S163	L160H	160	Missense	distal	-3	no	46.607	48.350	EPSD	COSMIC	39.062	Up-regulation
Other_Aur_AURKA_ST	P46937	YAP1	O14965	AURKA	S163	E166G	166	Missense	distal	3	no	46.607	46.490	EPSD	COSMIC	39.062	Down-regulation
Other_Aur_AURKA_ST	P46937	YAP1	O14965	AURKA	S164	D170N	170	Missense	distal	6	no	45.881	45.475	EPSD	COSMIC	39.062	Down-regulation
Other_Aur_AURKA_ST	P46937	YAP1	O14965	AURKA	S164	I167T	167	Missense	distal	3	no	45.881	42.863	EPSD	COSMIC	39.062	Down-regulation
Other_Aur_AURKA_ST	P46937	YAP1	O14965	AURKA	S164	Q162R	162	Missense	proximal	-2	no	45.881	56.520	EPSD	COSMIC	39.062	Up-regulation
Other_Aur_AURKA_ST	P46937	YAP1	O14965	AURKA	S164	L160H	160	Missense	distal	-4	no	45.881	41.410	EPSD	COSMIC	39.062	Down-regulation
Other_Aur_AURKA_ST	P46937	YAP1	O14965	AURKA	S164	E166G	166	Missense	proximal	2	no	45.881	45.591	EPSD	COSMIC	39.062	Down-regulation
Other_Aur_AURKA_ST	P46937	YAP1	O14965	AURKA	S274	V279L	279	Missense	distal	5	no	51.592	51.264	EPSD	COSMIC	39.062	Down-regulation
Other_Aur_AURKA_ST	P46937	YAP1	O14965	AURKA	S274	S274G	274	Missense	central	0	yes	51.592	0.000	EPSD	COSMIC	39.062	Loss
Other_Aur_AURKA_ST	P46937	YAP1	O14965	AURKA	S274	P278S	278	Missense	distal	4	no	51.592	51.646	EPSD	COSMIC	39.062	Up-regulation
Other_Aur_AURKA_ST	P46937	YAP1	O14965	AURKA	S274	S276R	276	Missense	proximal	2	no	51.592	50.387	EPSD	COSMIC	39.062	Down-regulation
Other_Aur_AURKA_ST	P46937	YAP1	O14965	AURKA	S274	A268V	268	Missense	distal	-6	no	51.592	50.756	EPSD	COSMIC	39.062	Down-regulation
Other_Aur_AURKA_ST	P46937	YAP1	O14965	AURKA	S274	Q281H	281	Missense	distal	7	no	51.592	51.655	EPSD	COSMIC	39.062	Up-regulation
Other_Aur_AURKA_ST	P46937	YAP1	O14965	AURKA	S371	T378I	378	Missense	distal	7	no	40.084	40.259	EPSD	COSMIC	39.062	Up-regulation
Other_Aur_AURKA_ST	P46937	YAP1	O14965	AURKA	S371	S371F	371	Missense	central	0	yes	40.084	0.000	EPSD	COSMIC	39.062	Loss
Other_Aur_AURKA_ST	P46937	YAP1	O14965	AURKA	S371	T376A	376	Missense	distal	5	no	40.084	39.452	EPSD	COSMIC	39.062	Down-regulation
Other_Aur_AURKA_ST	P46937	YAP1	O14965	AURKA	S371	T376P	376	Missense	distal	5	no	40.084	39.091	EPSD	COSMIC	39.062	Down-regulation
Other_Aur_AURKA_ST	P46937	YAP1	O14965	AURKA	S371	S367F	367	Missense	distal	-4	no	40.084	36.034	EPSD	COSMIC	39.062	Loss
Other_Aur_AURKA_ST	P46937	YAP1	O14965	AURKA	S371	T378M	378	Missense	distal	7	no	40.084	40.106	EPSD	COSMIC	39.062	Up-regulation
Other_Aur_AURKA_ST	P46937	YAP1	O14965	AURKA	S371	M377V	377	Missense	distal	6	no	40.084	39.925	EPSD	COSMIC	39.062	Down-regulation
Other_Aur_AURKA_ST	P46937	YAP1	O14965	AURKA	S371	M377I	377	Missense	distal	6	no	40.084	40.086	EPSD	COSMIC;GDSC;CCLE	39.062	Up-regulation
Other_Aur_AURKA_ST	P46937	YAP1	O14965	AURKA	T378	T376A	376	Missense	proximal	-2	no	37.869	45.444	EPSD	COSMIC	39.062	Gain
Other_Aur_AURKA_ST	P46937	YAP1	O14965	AURKA	T378	T376P	376	Missense	proximal	-2	no	37.869	42.023	EPSD	COSMIC	39.062	Gain
Other_Aur_AURKA_ST	P46937	YAP1	O14965	AURKA	T378	M377I	377	Missense	proximal	-1	no	37.869	39.243	EPSD	COSMIC;GDSC;CCLE	39.062	Gain
Other_Aur_AURKA_ST	P46937	YAP1	O14965	AURKA	S397	D399G	399	Missense	proximal	2	no	44.220	43.160	PhosphoSitePlus	COSMIC	39.062	Down-regulation
Other_Aur_AURKA_ST	P46937	YAP1	O14965	AURKA	S397	T390I	390	Missense	distal	-7	no	44.220	44.270	PhosphoSitePlus	COSMIC	39.062	Up-regulation
Other_Aur_AURKA_ST	P46937	YAP1	O14965	AURKA	S397	E396K	396	Missense	proximal	-1	no	44.220	44.640	PhosphoSitePlus	COSMIC	39.062	Up-regulation
Other_Aur_AURKA_ST	P46937	YAP1	O14965	AURKA	S397	D399H	399	Missense	proximal	2	no	44.220	40.684	PhosphoSitePlus	COSMIC	39.062	Down-regulation
Other_Aur_AURKA_ST	P46937	YAP1	O14965	AURKA	S397	D395G	395	Missense	proximal	-2	no	44.220	42.739	PhosphoSitePlus	COSMIC	39.062	Down-regulation
Other_Aur_AURKA_ST	P46937	YAP1	O14965	AURKA	S419	N418T	418	Missense	proximal	-1	no	40.480	44.022	EPSD	COSMIC	39.062	Up-regulation
Other_Aur_AURKA_ST	P46937	YAP1	O14965	AURKA	S419	F416L	416	Missense	distal	-3	no	40.480	45.060	EPSD	COSMIC	39.062	Up-regulation
Other_Aur_AURKA_ST	Q92974	ARHGEF2	O14965	AURKA	T103	A104T	104	Missense	proximal	1	no	39.405	37.733	EPSD	COSMIC;CCLE	39.062	Loss
Other_Aur_AURKA_ST	Q92974	ARHGEF2	O14965	AURKA	T103	K100M	100	Missense	distal	-3	no	39.405	34.333	EPSD	COSMIC	39.062	Loss
Other_Aur_AURKA_ST	Q92974	ARHGEF2	O14965	AURKA	T103	A96V	96	Missense	distal	-7	no	39.405	39.537	EPSD	COSMIC	39.062	Up-regulation
Other_Aur_AURKA_ST	Q92974	ARHGEF2	O14965	AURKA	S121	S122L	122	Missense	proximal	1	no	36.538	42.188	EPSD	COSMIC	39.062	Gain
Other_Aur_AURKA_ST	Q92974	ARHGEF2	O14965	AURKA	S133	S137F	137	Missense	distal	4	no	39.533	40.016	EPSD	COSMIC	39.062	Up-regulation
Other_Aur_AURKA_ST	Q92974	ARHGEF2	O14965	AURKA	S133	R131W	131	Missense	proximal	-2	no	39.533	-147.175	EPSD	COSMIC;CCLE	39.062	Loss
Other_Aur_AURKA_ST	Q92974	ARHGEF2	O14965	AURKA	S133	D128Y	128	Missense	distal	-5	no	39.533	39.527	EPSD	COSMIC	39.062	Down-regulation
Other_Aur_AURKA_ST	Q92974	ARHGEF2	O14965	AURKA	S133	D128E	128	Missense	distal	-5	no	39.533	39.514	EPSD	COSMIC	39.062	Down-regulation
Other_Aur_AURKA_ST	Q92974	ARHGEF2	O14965	AURKA	S133	R138S	138	Missense	distal	5	no	39.533	40.685	EPSD	COSMIC	39.062	Up-regulation
Other_Aur_AURKA_ST	Q92974	ARHGEF2	O14965	AURKA	S142	S137F	137	Missense	distal	-5	no	47.482	47.488	EPSD	COSMIC	39.062	Up-regulation
Other_Aur_AURKA_ST	Q92974	ARHGEF2	O14965	AURKA	S142	R138S	138	Missense	distal	-4	no	47.482	48.283	EPSD	COSMIC	39.062	Up-regulation
Other_Aur_AURKA_ST	Q92974	ARHGEF2	O14965	AURKA	S142	R141S	141	Missense	proximal	-1	no	47.482	47.493	EPSD	COSMIC	39.062	Up-regulation
Other_Aur_AURKA_ST	Q92974	ARHGEF2	O14965	AURKA	S142	R141C	141	Missense	proximal	-1	no	47.482	47.265	EPSD	COSMIC	39.062	Down-regulation
Other_Aur_AURKA_ST	Q92974	ARHGEF2	O14965	AURKA	S142	R141L	141	Missense	proximal	-1	no	47.482	45.923	EPSD	COSMIC	39.062	Down-regulation
Other_Aur_AURKA_ST	Q92974	ARHGEF2	O14965	AURKA	S143	S137F	137	Missense	distal	-6	no	47.935	42.277	EPSD	COSMIC	39.062	Down-regulation
Other_Aur_AURKA_ST	Q92974	ARHGEF2	O14965	AURKA	S143	R138S	138	Missense	distal	-5	no	47.935	47.931	EPSD	COSMIC	39.062	Down-regulation
Other_Aur_AURKA_ST	Q92974	ARHGEF2	O14965	AURKA	S143	R141S	141	Missense	proximal	-2	no	47.935	34.777	EPSD	COSMIC	39.062	Loss
Other_Aur_AURKA_ST	Q92974	ARHGEF2	O14965	AURKA	S143	R141C	141	Missense	proximal	-2	no	47.935	32.638	EPSD	COSMIC	39.062	Loss
Other_Aur_AURKA_ST	Q92974	ARHGEF2	O14965	AURKA	S143	R141L	141	Missense	proximal	-2	no	47.935	38.215	EPSD	COSMIC	39.062	Loss
Other_Aur_AURKA_ST	Q92974	ARHGEF2	O14965	AURKA	S172	T175K	175	Missense	distal	3	no	38.856	39.757	EPSD	COSMIC	39.062	Gain
Other_Aur_AURKA_ST	Q92974	ARHGEF2	O14965	AURKA	S177	T175K	175	Missense	proximal	-2	no	33.608	46.318	EPSD	COSMIC	39.062	Gain
Other_Aur_AURKA_ST	Q92974	ARHGEF2	O14965	AURKA	S186	R183S	183	Missense	distal	-3	no	42.760	36.281	EPSD	COSMIC	39.062	Loss
Other_Aur_AURKA_ST	Q92974	ARHGEF2	O14965	AURKA	S186	S186F	186	Missense	central	0	yes	42.760	0.000	EPSD	COSMIC	39.062	Loss
Other_Aur_AURKA_ST	Q92974	ARHGEF2	O14965	AURKA	S696	D690H	690	Missense	distal	-6	no	43.927	45.603	EPSD	COSMIC	39.062	Up-regulation
Other_Aur_AURKA_ST	Q92974	ARHGEF2	O14965	AURKA	S696	G703A	703	Missense	distal	7	no	43.927	43.754	EPSD	COSMIC	39.062	Down-regulation
Other_Aur_AURKA_ST	Q92974	ARHGEF2	O14965	AURKA	S733	L731V	731	Missense	proximal	-2	no	45.168	43.849	EPSD	COSMIC	39.062	Down-regulation
Other_Aur_AURKA_ST	Q92974	ARHGEF2	O14965	AURKA	S733	P734Q	734	Missense	proximal	1	no	45.168	48.279	EPSD	COSMIC	39.062	Up-regulation
Other_Aur_AURKA_ST	Q92974	ARHGEF2	O14965	AURKA	S733	S733L	733	Missense	central	0	yes	45.168	0.000	EPSD	COSMIC	39.062	Loss
Other_Aur_AURKA_ST	Q92974	ARHGEF2	O14965	AURKA	S886	R885W	885	Missense	proximal	-1	no	55.637	59.312	PhosphoSitePlus	COSMIC	39.062	Up-regulation
Other_Aur_AURKA_ST	Q92974	ARHGEF2	O14965	AURKA	S886	R883Q	883	Missense	distal	-3	no	55.637	45.974	PhosphoSitePlus	COSMIC	39.062	Down-regulation
Other_Aur_AURKA_ST	Q92974	ARHGEF2	O14965	AURKA	S886	R884C	884	Missense	proximal	-2	no	55.637	40.340	PhosphoSitePlus	COSMIC	39.062	Down-regulation
Other_Aur_AURKA_ST	Q92974	ARHGEF2	O14965	AURKA	S886	R884H	884	Missense	proximal	-2	no	55.637	48.399	PhosphoSitePlus	COSMIC	39.062	Down-regulation
Other_Aur_AURKA_ST	Q92974	ARHGEF2	O14965	AURKA	S886	R885C	885	Missense	proximal	-1	no	55.637	55.421	PhosphoSitePlus	COSMIC;CCLE	39.062	Down-regulation
Other_Aur_AURKA_ST	Q92974	ARHGEF2	O14965	AURKA	S886	L887F	887	Missense	proximal	1	no	55.637	56.467	PhosphoSitePlus	COSMIC	39.062	Up-regulation
Other_Aur_AURKA_ST	Q92974	ARHGEF2	O14965	AURKA	S886	P882L	882	Missense	distal	-4	no	55.637	56.789	PhosphoSitePlus	COSMIC	39.062	Up-regulation
Other_Aur_AURKA_ST	Q92974	ARHGEF2	O14965	AURKA	S886	P888S	888	Missense	proximal	2	no	55.637	56.885	PhosphoSitePlus	COSMIC	39.062	Up-regulation
Other_Aur_AURKA_ST	Q92974	ARHGEF2	O14965	AURKA	S886	P888L	888	Missense	proximal	2	no	55.637	55.906	PhosphoSitePlus	COSMIC	39.062	Up-regulation
Other_Aur_AURKA_ST	Q92974	ARHGEF2	O14965	AURKA	S903	R908W	908	Missense	distal	5	no	38.848	39.847	EPSD	COSMIC	39.062	Gain
Other_Aur_AURKA_ST	Q92974	ARHGEF2	O14965	AURKA	S903	R908C	908	Missense	distal	5	no	38.848	40.998	EPSD	COSMIC	39.062	Gain
Other_Aur_AURKA_ST	Q92974	ARHGEF2	O14965	AURKA	S903	R904Q	904	Missense	proximal	1	no	38.848	39.739	EPSD	COSMIC	39.062	Gain
Other_Aur_AURKA_ST	Q92974	ARHGEF2	O14965	AURKA	S956	S952R	952	Missense	distal	-4	no	42.134	41.332	EPSD	COSMIC	39.062	Down-regulation
Other_Aur_AURKA_ST	Q92974	ARHGEF2	O14965	AURKA	S956	G951E	951	Missense	distal	-5	no	42.134	42.147	EPSD	COSMIC	39.062	Up-regulation
Other_Aur_AURKA_ST	Q92974	ARHGEF2	O14965	AURKA	S956	S952T	952	Missense	distal	-4	no	42.134	44.130	EPSD	COSMIC	39.062	Up-regulation
Other_Aur_AURKA_ST	Q92974	ARHGEF2	O14965	AURKA	S956	L955V	955	Missense	proximal	-1	no	42.134	42.545	EPSD	COSMIC	39.062	Up-regulation
Other_Aur_AURKA_ST	P38398	BRCA1	O14965	AURKA	S114	P115L	115	Missense	proximal	1	no	35.856	40.506	EPSD	COSMIC	39.062	Gain
Other_Aur_AURKA_ST	P38398	BRCA1	O14965	AURKA	S184	G183A	183	Missense	proximal	-1	no	40.926	40.979	EPSD	COSMIC	39.062	Up-regulation
Other_Aur_AURKA_ST	P38398	BRCA1	O14965	AURKA	S184	Y179H	179	Missense	distal	-5	no	40.926	40.862	EPSD	COSMIC	39.062	Down-regulation
Other_Aur_AURKA_ST	P38398	BRCA1	O14965	AURKA	S184	L182S	182	Missense	proximal	-2	no	40.926	37.488	EPSD	COSMIC	39.062	Loss
Other_Aur_AURKA_ST	P38398	BRCA1	O14965	AURKA	S184	Y179C	179	Missense	distal	-5	no	40.926	41.042	EPSD	COSMIC	39.062	Up-regulation
Other_Aur_AURKA_ST	P38398	BRCA1	O14965	AURKA	S308	P311A	311	Missense	distal	3	no	41.070	40.267	PhosphoSitePlus	COSMIC	39.062	Down-regulation
Other_Aur_AURKA_ST	P38398	BRCA1	O14965	AURKA	S308	K309Q	309	Missense	proximal	1	no	41.070	41.296	PhosphoSitePlus	COSMIC	39.062	Up-regulation
Other_Aur_AURKA_ST	P38398	BRCA1	O14965	AURKA	S308	Q310H	310	Missense	proximal	2	no	41.070	37.965	PhosphoSitePlus	COSMIC	39.062	Loss
Other_Aur_AURKA_ST	P38398	BRCA1	O14965	AURKA	S308	A314S	314	Missense	distal	6	no	41.070	41.062	PhosphoSitePlus	COSMIC	39.062	Down-regulation
Other_Aur_AURKA_ST	P38398	BRCA1	O14965	AURKA	S378	I373L	373	Missense	distal	-5	no	41.436	41.428	EPSD	COSMIC	39.062	Down-regulation
Other_Aur_AURKA_ST	P38398	BRCA1	O14965	AURKA	S378	T374A	374	Missense	distal	-4	no	41.436	36.477	EPSD	COSMIC	39.062	Loss
Other_Aur_AURKA_ST	P38398	BRCA1	O14965	AURKA	S378	E384V	384	Missense	distal	6	no	41.436	41.407	EPSD	COSMIC	39.062	Down-regulation
Other_Aur_AURKA_ST	P38398	BRCA1	O14965	AURKA	S378	Q380E	380	Missense	proximal	2	no	41.436	41.096	EPSD	COSMIC	39.062	Down-regulation
Other_Aur_AURKA_ST	P38398	BRCA1	O14965	AURKA	S378	L375V	375	Missense	distal	-3	no	41.436	43.789	EPSD	COSMIC	39.062	Up-regulation
Other_Aur_AURKA_ST	P38398	BRCA1	O14965	AURKA	S395	G401E	401	Missense	distal	6	no	41.795	41.736	EPSD	COSMIC;GDSC;CCLE	39.062	Down-regulation
Other_Aur_AURKA_ST	P38398	BRCA1	O14965	AURKA	S395	H399R	399	Missense	distal	4	no	41.795	41.125	EPSD	COSMIC	39.062	Down-regulation
Other_Aur_AURKA_ST	P38398	BRCA1	O14965	AURKA	S395	S395F	395	Missense	central	0	yes	41.795	0.000	EPSD	COSMIC	39.062	Loss
Other_Aur_AURKA_ST	P38398	BRCA1	O14965	AURKA	S395	G401V	401	Missense	distal	6	no	41.795	41.707	EPSD	COSMIC	39.062	Down-regulation
Other_Aur_AURKA_ST	P38398	BRCA1	O14965	AURKA	S398	G401E	401	Missense	distal	3	no	41.810	41.927	EPSD	COSMIC;GDSC;CCLE	39.062	Up-regulation
Other_Aur_AURKA_ST	P38398	BRCA1	O14965	AURKA	S398	H399R	399	Missense	proximal	1	no	41.810	43.798	EPSD	COSMIC	39.062	Up-regulation
Other_Aur_AURKA_ST	P38398	BRCA1	O14965	AURKA	S398	S395F	395	Missense	distal	-3	no	41.810	36.194	EPSD	COSMIC	39.062	Loss
Other_Aur_AURKA_ST	P38398	BRCA1	O14965	AURKA	S398	G401V	401	Missense	distal	3	no	41.810	40.640	EPSD	COSMIC	39.062	Down-regulation
Other_Aur_AURKA_ST	P38398	BRCA1	O14965	AURKA	S449	H448R	448	Missense	proximal	-1	no	47.447	47.856	EPSD	COSMIC	39.062	Up-regulation
Other_Aur_AURKA_ST	P38398	BRCA1	O14965	AURKA	S449	K443E	443	Missense	distal	-6	no	47.447	46.264	EPSD	COSMIC	39.062	Down-regulation
Other_Aur_AURKA_ST	P38398	BRCA1	O14965	AURKA	S449	N455T	455	Missense	distal	6	no	47.447	47.607	EPSD	COSMIC	39.062	Up-regulation
Other_Aur_AURKA_ST	P38398	BRCA1	O14965	AURKA	S449	I456T	456	Missense	distal	7	no	47.447	47.271	EPSD	COSMIC;GDSC;CCLE	39.062	Down-regulation
Other_Aur_AURKA_ST	P38398	BRCA1	O14965	AURKA	T509	R506S	506	Missense	distal	-3	no	43.947	37.467	EPSD	COSMIC	39.062	Loss
Other_Aur_AURKA_ST	P38398	BRCA1	O14965	AURKA	T509	R504C	504	Missense	distal	-5	no	43.947	44.069	EPSD	COSMIC	39.062	Up-regulation
Other_Aur_AURKA_ST	P38398	BRCA1	O14965	AURKA	T509	S510L	510	Missense	proximal	1	no	43.947	49.596	EPSD	COSMIC	39.062	Up-regulation
Other_Aur_AURKA_ST	P38398	BRCA1	O14965	AURKA	T509	L512F	512	Missense	distal	3	no	43.947	45.116	EPSD	COSMIC	39.062	Up-regulation
Other_Aur_AURKA_ST	P38398	BRCA1	O14965	AURKA	T509	R507K	507	Missense	proximal	-2	no	43.947	37.443	EPSD	COSMIC	39.062	Loss
Other_Aur_AURKA_ST	P38398	BRCA1	O14965	AURKA	T509	R507I	507	Missense	proximal	-2	no	43.947	24.917	EPSD	COSMIC	39.062	Loss
Other_Aur_AURKA_ST	P38398	BRCA1	O14965	AURKA	S615	H619N	619	Missense	distal	4	no	46.957	45.944	EPSD	COSMIC	39.062	Down-regulation
Other_Aur_AURKA_ST	P38398	BRCA1	O14965	AURKA	S615	R613K	613	Missense	proximal	-2	no	46.957	40.453	EPSD	COSMIC	39.062	Down-regulation
Other_Aur_AURKA_ST	P38398	BRCA1	O14965	AURKA	S615	K608N	608	Missense	distal	-7	no	46.957	46.659	EPSD	COSMIC	39.062	Down-regulation
Other_Aur_AURKA_ST	P38398	BRCA1	O14965	AURKA	S615	R610S	610	Missense	distal	-5	no	46.957	46.952	EPSD	COSMIC	39.062	Down-regulation
Other_Aur_AURKA_ST	P38398	BRCA1	O14965	AURKA	S615	S616N	616	Missense	proximal	1	no	46.957	45.460	EPSD	COSMIC	39.062	Down-regulation
Other_Aur_AURKA_ST	P38398	BRCA1	O14965	AURKA	S632	N630H	630	Missense	proximal	-2	no	38.855	42.099	EPSD	COSMIC	39.062	Gain
Other_Aur_AURKA_ST	P38398	BRCA1	O14965	AURKA	S632	P634S	634	Missense	proximal	2	no	38.855	40.103	EPSD	COSMIC	39.062	Gain
Other_Aur_AURKA_ST	P38398	BRCA1	O14965	AURKA	S632	S628N	628	Missense	distal	-4	no	38.855	39.406	EPSD	COSMIC	39.062	Gain
Other_Aur_AURKA_ST	P38398	BRCA1	O14965	AURKA	S632	E638D	638	Missense	distal	6	no	38.855	39.065	EPSD	COSMIC	39.062	Gain
Other_Aur_AURKA_ST	P38398	BRCA1	O14965	AURKA	S632	C636F	636	Missense	distal	4	no	38.855	39.896	EPSD	COSMIC	39.062	Gain
Other_Aur_AURKA_ST	P38398	BRCA1	O14965	AURKA	T637	P634R	634	Missense	distal	-3	no	33.578	42.237	EPSD	COSMIC	39.062	Gain
Other_Aur_AURKA_ST	P38398	BRCA1	O14965	AURKA	S694	Q687P	687	Missense	distal	-7	no	38.308	40.117	EPSD	COSMIC;GDSC;CCLE	39.062	Gain
Other_Aur_AURKA_ST	P38398	BRCA1	O14965	AURKA	S741	N742S	742	Missense	proximal	1	no	38.555	40.052	EPSD	COSMIC;GDSC;CCLE	39.062	Gain
Other_Aur_AURKA_ST	P38398	BRCA1	O14965	AURKA	S840	E842K	842	Missense	proximal	2	no	44.410	41.346	EPSD	COSMIC	39.062	Down-regulation
Other_Aur_AURKA_ST	P38398	BRCA1	O14965	AURKA	S840	R841W	841	Missense	proximal	1	no	44.410	41.838	EPSD	COSMIC	39.062	Down-regulation
Other_Aur_AURKA_ST	P38398	BRCA1	O14965	AURKA	S840	T843A	843	Missense	distal	3	no	44.410	45.542	EPSD	COSMIC;GDSC;CCLE	39.062	Up-regulation
Other_Aur_AURKA_ST	P38398	BRCA1	O14965	AURKA	S844	E842K	842	Missense	proximal	-2	no	41.686	55.829	EPSD	COSMIC	39.062	Up-regulation
Other_Aur_AURKA_ST	P38398	BRCA1	O14965	AURKA	S844	R841W	841	Missense	distal	-3	no	41.686	-37.486	EPSD	COSMIC	39.062	Loss
Other_Aur_AURKA_ST	P38398	BRCA1	O14965	AURKA	S844	E849G	849	Missense	distal	5	no	41.686	41.781	EPSD	COSMIC	39.062	Up-regulation
Other_Aur_AURKA_ST	P38398	BRCA1	O14965	AURKA	S844	T843A	843	Missense	proximal	-1	no	41.686	40.097	EPSD	COSMIC;GDSC;CCLE	39.062	Down-regulation
Other_Aur_AURKA_ST	P38398	BRCA1	O14965	AURKA	S868	P871L	871	Missense	distal	3	no	42.885	42.421	EPSD	COSMIC	39.062	Down-regulation
Other_Aur_AURKA_ST	P38398	BRCA1	O14965	AURKA	S868	S868L	868	Missense	central	0	yes	42.885	0.000	EPSD	COSMIC	39.062	Loss
Other_Aur_AURKA_ST	P38398	BRCA1	O14965	AURKA	S868	S864L	864	Missense	distal	-4	no	42.885	42.119	EPSD	COSMIC	39.062	Down-regulation
Other_Aur_AURKA_ST	P38398	BRCA1	O14965	AURKA	S868	K865N	865	Missense	distal	-3	no	42.885	44.875	EPSD	COSMIC	39.062	Up-regulation
Other_Aur_AURKA_ST	P38398	BRCA1	O14965	AURKA	S1024	R1028H	1028	Missense	distal	4	no	38.446	39.116	EPSD	COSMIC	39.062	Gain
Other_Aur_AURKA_ST	P38398	BRCA1	O14965	AURKA	S1024	P1020L	1020	Missense	distal	-4	no	38.446	39.597	EPSD	COSMIC	39.062	Gain
Other_Aur_AURKA_ST	P38398	BRCA1	O14965	AURKA	S1097	P1099S	1099	Missense	proximal	2	no	46.272	47.520	EPSD	COSMIC	39.062	Up-regulation
Other_Aur_AURKA_ST	P38398	BRCA1	O14965	AURKA	S1097	L1098I	1098	Missense	proximal	1	no	46.272	42.799	EPSD	COSMIC	39.062	Down-regulation
Other_Aur_AURKA_ST	P38398	BRCA1	O14965	AURKA	S1097	K1104E	1104	Missense	distal	7	no	46.272	46.383	EPSD	COSMIC	39.062	Up-regulation
Other_Aur_AURKA_ST	P38398	BRCA1	O14965	AURKA	S1097	V1093I	1093	Missense	distal	-4	no	46.272	39.849	EPSD	COSMIC	39.062	Down-regulation
Other_Aur_AURKA_ST	P38398	BRCA1	O14965	AURKA	S1097	E1092V	1092	Missense	distal	-5	no	46.272	46.270	EPSD	COSMIC	39.062	Down-regulation
Other_Aur_AURKA_ST	P38398	BRCA1	O14965	AURKA	S1143	S1140G	1140	Missense	distal	-3	no	42.911	44.197	EPSD	COSMIC;GDSC	39.062	Up-regulation
Other_Aur_AURKA_ST	P38398	BRCA1	O14965	AURKA	S1143	G1138E	1138	Missense	distal	-5	no	42.911	42.925	EPSD	COSMIC	39.062	Up-regulation
Other_Aur_AURKA_ST	P38398	BRCA1	O14965	AURKA	S1143	P1150S	1150	Missense	distal	7	no	42.911	43.021	EPSD	COSMIC	39.062	Up-regulation
Other_Aur_AURKA_ST	P38398	BRCA1	O14965	AURKA	S1164	T1163A	1163	Missense	proximal	-1	no	40.855	39.265	EPSD	COSMIC	39.062	Down-regulation
Other_Aur_AURKA_ST	P38398	BRCA1	O14965	AURKA	S1164	E1167K	1167	Missense	distal	3	no	40.855	39.459	EPSD	COSMIC	39.062	Down-regulation
Other_Aur_AURKA_ST	P38398	BRCA1	O14965	AURKA	S1178	S1180I	1180	Missense	proximal	2	no	40.638	39.852	EPSD	COSMIC	39.062	Down-regulation
Other_Aur_AURKA_ST	P38398	BRCA1	O14965	AURKA	S1178	K1183R	1183	Missense	distal	5	no	40.638	38.952	EPSD	COSMIC	39.062	Loss
Other_Aur_AURKA_ST	P38398	BRCA1	O14965	AURKA	S1178	E1185Q	1185	Missense	distal	7	no	40.638	40.514	EPSD	COSMIC	39.062	Down-regulation
Other_Aur_AURKA_ST	P38398	BRCA1	O14965	AURKA	S1178	Q1182H	1182	Missense	distal	4	no	40.638	40.894	EPSD	COSMIC	39.062	Up-regulation
Other_Aur_AURKA_ST	P38398	BRCA1	O14965	AURKA	S1187	E1185Q	1185	Missense	proximal	-2	no	29.199	39.206	EPSD	COSMIC	39.062	Gain
Other_Aur_AURKA_ST	P38398	BRCA1	O14965	AURKA	S1189	K1183R	1183	Missense	distal	-6	no	41.023	44.007	EPSD	COSMIC	39.062	Up-regulation
Other_Aur_AURKA_ST	P38398	BRCA1	O14965	AURKA	S1189	E1185Q	1185	Missense	distal	-4	no	41.023	39.659	EPSD	COSMIC	39.062	Down-regulation
Other_Aur_AURKA_ST	P38398	BRCA1	O14965	AURKA	S1189	P1190H	1190	Missense	proximal	1	no	41.023	41.254	EPSD	COSMIC;GDSC;CCLE	39.062	Up-regulation
Other_Aur_AURKA_ST	P38398	BRCA1	O14965	AURKA	S1189	P1190F	1190	Missense	proximal	1	no	41.023	46.503	EPSD	COSMIC	39.062	Up-regulation
Other_Aur_AURKA_ST	P38398	BRCA1	O14965	AURKA	S1189	Q1182H	1182	Missense	distal	-7	no	41.023	40.070	EPSD	COSMIC	39.062	Down-regulation
Other_Aur_AURKA_ST	P38398	BRCA1	O14965	AURKA	S1189	P1192F	1192	Missense	distal	3	no	41.023	41.729	EPSD	COSMIC	39.062	Up-regulation
Other_Aur_AURKA_ST	P38398	BRCA1	O14965	AURKA	S1189	P1190L	1190	Missense	proximal	1	no	41.023	45.673	EPSD	COSMIC	39.062	Up-regulation
Other_Aur_AURKA_ST	P38398	BRCA1	O14965	AURKA	S1189	P1192S	1192	Missense	distal	3	no	41.023	41.674	EPSD	COSMIC	39.062	Up-regulation
Other_Aur_AURKA_ST	P38398	BRCA1	O14965	AURKA	S1189	P1192L	1192	Missense	distal	3	no	41.023	40.559	EPSD	COSMIC	39.062	Down-regulation
Other_Aur_AURKA_ST	P38398	BRCA1	O14965	AURKA	S1189	R1188K	1188	Missense	proximal	-1	no	41.023	40.675	EPSD	COSMIC	39.062	Down-regulation
Other_Aur_AURKA_ST	P38398	BRCA1	O14965	AURKA	S1211	E1214K	1214	Missense	distal	3	no	40.404	39.008	EPSD	COSMIC	39.062	Loss
Other_Aur_AURKA_ST	P38398	BRCA1	O14965	AURKA	S1211	K1208T	1208	Missense	distal	-3	no	40.404	38.614	EPSD	COSMIC	39.062	Loss
Other_Aur_AURKA_ST	P38398	BRCA1	O14965	AURKA	S1211	S1212P	1212	Missense	proximal	1	no	40.404	41.404	EPSD	COSMIC	39.062	Up-regulation
Other_Aur_AURKA_ST	P38398	BRCA1	O14965	AURKA	S1211	R1204K	1204	Missense	distal	-7	no	40.404	39.465	EPSD	COSMIC	39.062	Down-regulation
Other_Aur_AURKA_ST	P38398	BRCA1	O14965	AURKA	S1211	E1210K	1210	Missense	proximal	-1	no	40.404	40.824	EPSD	COSMIC	39.062	Up-regulation
Other_Aur_AURKA_ST	P38398	BRCA1	O14965	AURKA	S1211	K1207T	1207	Missense	distal	-4	no	40.404	41.494	EPSD	COSMIC	39.062	Up-regulation
Other_Aur_AURKA_ST	P38398	BRCA1	O14965	AURKA	T1246	Q1240E	1240	Missense	distal	-6	no	43.578	40.277	EPSD	COSMIC	39.062	Down-regulation
Other_Aur_AURKA_ST	P38398	BRCA1	O14965	AURKA	T1246	S1245N	1245	Missense	proximal	-1	no	43.578	41.739	EPSD	COSMIC	39.062	Down-regulation
Other_Aur_AURKA_ST	P38398	BRCA1	O14965	AURKA	T1246	H1244Y	1244	Missense	proximal	-2	no	43.578	36.941	EPSD	COSMIC	39.062	Loss
Other_Aur_AURKA_ST	P38398	BRCA1	O14965	AURKA	T1246	Q1240L	1240	Missense	distal	-6	no	43.578	41.884	EPSD	COSMIC	39.062	Down-regulation
Other_Aur_AURKA_ST	P38398	BRCA1	O14965	AURKA	T1246	L1252Q	1252	Missense	distal	6	no	43.578	43.580	EPSD	COSMIC	39.062	Up-regulation
Other_Aur_AURKA_ST	P38398	BRCA1	O14965	AURKA	T1246	S1241F	1241	Missense	distal	-5	no	43.578	43.585	EPSD	COSMIC	39.062	Up-regulation
Other_Aur_AURKA_ST	P38398	BRCA1	O14965	AURKA	T1246	T1246A	1246	Missense	central	0	yes	43.578	0.000	EPSD	COSMIC	39.062	Loss
Other_Aur_AURKA_ST	P38398	BRCA1	O14965	AURKA	T1246	T1249P	1249	Missense	distal	3	no	43.578	45.513	EPSD	COSMIC	39.062	Up-regulation
Other_Aur_AURKA_ST	P38398	BRCA1	O14965	AURKA	T1246	S1245Y	1245	Missense	proximal	-1	no	43.578	42.635	EPSD	COSMIC	39.062	Down-regulation
Other_Aur_AURKA_ST	P38398	BRCA1	O14965	AURKA	T1246	S1245A	1245	Missense	proximal	-1	no	43.578	43.691	EPSD	COSMIC	39.062	Up-regulation
Other_Aur_AURKA_ST	P38398	BRCA1	O14965	AURKA	T1246	S1239T	1239	Missense	distal	-7	no	43.578	43.005	EPSD	COSMIC	39.062	Down-regulation
Other_Aur_AURKA_ST	P38398	BRCA1	O14965	AURKA	T1246	S1245F	1245	Missense	proximal	-1	no	43.578	44.651	EPSD	COSMIC	39.062	Up-regulation
Other_Aur_AURKA_ST	P38398	BRCA1	O14965	AURKA	S1262	L1260V	1260	Missense	proximal	-2	no	40.323	39.004	EPSD	COSMIC	39.062	Loss
Other_Aur_AURKA_ST	P38398	BRCA1	O14965	AURKA	S1262	L1263F	1263	Missense	proximal	1	no	40.323	41.153	EPSD	COSMIC	39.062	Up-regulation
Other_Aur_AURKA_ST	P38398	BRCA1	O14965	AURKA	S1262	N1255K	1255	Missense	distal	-7	no	40.323	40.621	EPSD	COSMIC	39.062	Up-regulation
Other_Aur_AURKA_ST	P38398	BRCA1	O14965	AURKA	S1262	E1257K	1257	Missense	distal	-5	no	40.323	40.304	EPSD	COSMIC	39.062	Down-regulation
Other_Aur_AURKA_ST	P38398	BRCA1	O14965	AURKA	S1262	K1264N	1264	Missense	proximal	2	no	40.323	42.366	EPSD	COSMIC	39.062	Up-regulation
Other_Aur_AURKA_ST	P38398	BRCA1	O14965	AURKA	S1286	S1292F	1292	Missense	distal	6	no	41.144	41.289	EPSD	COSMIC	39.062	Up-regulation
Other_Aur_AURKA_ST	P38398	BRCA1	O14965	AURKA	S1286	S1292A	1292	Missense	distal	6	no	41.144	41.151	EPSD	COSMIC	39.062	Up-regulation
Other_Aur_AURKA_ST	P38398	BRCA1	O14965	AURKA	S1286	H1284Y	1284	Missense	proximal	-2	no	41.144	34.506	EPSD	COSMIC	39.062	Loss
Other_Aur_AURKA_ST	P38398	BRCA1	O14965	AURKA	S1286	S1292Y	1292	Missense	distal	6	no	41.144	41.074	EPSD	COSMIC	39.062	Down-regulation
Other_Aur_AURKA_ST	P38398	BRCA1	O14965	AURKA	S1480	E1478Q	1478	Missense	proximal	-2	no	29.201	39.208	EPSD	COSMIC	39.062	Gain
Other_Aur_AURKA_ST	P38398	BRCA1	O14965	AURKA	S1486	S1483C	1483	Missense	distal	-3	no	38.428	40.371	EPSD	COSMIC	39.062	Gain
Other_Aur_AURKA_ST	P38398	BRCA1	O14965	AURKA	S1497	P1491L	1491	Missense	distal	-6	no	46.425	45.444	EPSD	COSMIC	39.062	Down-regulation
Other_Aur_AURKA_ST	P38398	BRCA1	O14965	AURKA	S1497	P1502L	1502	Missense	distal	5	no	46.425	45.841	EPSD	COSMIC	39.062	Down-regulation
Other_Aur_AURKA_ST	P38398	BRCA1	O14965	AURKA	S1497	S1499F	1499	Missense	proximal	2	no	46.425	45.729	EPSD	COSMIC	39.062	Down-regulation
Other_Aur_AURKA_ST	P38398	BRCA1	O14965	AURKA	S1497	E1490Q	1490	Missense	distal	-7	no	46.425	47.486	EPSD	COSMIC	39.062	Up-regulation
Other_Aur_AURKA_ST	P38398	BRCA1	O14965	AURKA	S1497	S1497P	1497	Missense	central	0	yes	46.425	0.000	EPSD	COSMIC	39.062	Loss
Other_Aur_AURKA_ST	P38398	BRCA1	O14965	AURKA	S1497	V1493E	1493	Missense	distal	-4	no	46.425	46.428	EPSD	COSMIC	39.062	Up-regulation
Other_Aur_AURKA_ST	P38398	BRCA1	O14965	AURKA	S1569	S1569G	1569	Missense	central	0	yes	39.117	0.000	EPSD	COSMIC	39.062	Loss
Other_Aur_AURKA_ST	P38398	BRCA1	O14965	AURKA	S1569	L1564P	1564	Missense	distal	-5	no	39.117	39.104	EPSD	COSMIC	39.062	Down-regulation
Other_Aur_AURKA_ST	P38398	BRCA1	O14965	AURKA	S1569	P1562L	1562	Missense	distal	-7	no	39.117	37.444	EPSD	COSMIC	39.062	Loss
Other_Aur_AURKA_ST	P38398	BRCA1	O14965	AURKA	S1569	L1570P	1570	Missense	proximal	1	no	39.117	34.467	EPSD	COSMIC	39.062	Loss
Other_Aur_AURKA_ST	P38398	BRCA1	O14965	AURKA	S1569	P1562T	1562	Missense	distal	-7	no	39.117	36.683	EPSD	COSMIC	39.062	Loss
Other_Aur_AURKA_ST	P38398	BRCA1	O14965	AURKA	S1569	I1568S	1568	Missense	proximal	-1	no	39.117	37.623	EPSD	COSMIC	39.062	Loss
Other_Aur_AURKA_ST	P38398	BRCA1	O14965	AURKA	S1569	S1566G	1566	Missense	distal	-3	no	39.117	40.402	EPSD	COSMIC	39.062	Up-regulation
Other_Aur_AURKA_ST	P38398	BRCA1	O14965	AURKA	S1569	S1572C	1572	Missense	distal	3	no	39.117	36.779	EPSD	COSMIC	39.062	Loss
Other_Aur_AURKA_ST	P38398	BRCA1	O14965	AURKA	S1569	S1572T	1572	Missense	distal	3	no	39.117	36.530	EPSD	COSMIC	39.062	Loss
Other_Aur_AURKA_ST	P38398	BRCA1	O14965	AURKA	S1580	S1587P	1587	Missense	distal	7	no	43.247	43.137	EPSD	COSMIC	39.062	Down-regulation
Other_Aur_AURKA_ST	P38398	BRCA1	O14965	AURKA	S1580	D1578H	1578	Missense	proximal	-2	no	43.247	44.671	EPSD	COSMIC	39.062	Up-regulation
Other_Aur_AURKA_ST	P38398	BRCA1	O14965	AURKA	S1580	D1582E	1582	Missense	proximal	2	no	43.247	42.477	EPSD	COSMIC	39.062	Down-regulation
Other_Aur_AURKA_ST	P38398	BRCA1	O14965	AURKA	S1580	E1581K	1581	Missense	proximal	1	no	43.247	45.271	EPSD	COSMIC	39.062	Up-regulation
Other_Aur_AURKA_ST	P38398	BRCA1	O14965	AURKA	S1580	D1582N	1582	Missense	proximal	2	no	43.247	41.456	EPSD	COSMIC	39.062	Down-regulation
Other_Aur_AURKA_ST	P38398	BRCA1	O14965	AURKA	S1580	S1577P	1577	Missense	distal	-3	no	43.247	41.067	EPSD	COSMIC;GDSC;CCLE	39.062	Down-regulation
Other_Aur_AURKA_ST	P38398	BRCA1	O14965	AURKA	S1598	P1603T	1603	Missense	distal	5	no	38.883	39.876	EPSD	COSMIC	39.062	Gain
Other_Aur_AURKA_ST	P38398	BRCA1	O14965	AURKA	S1610	S1613G	1613	Missense	distal	3	no	42.672	42.265	EPSD	COSMIC	39.062	Down-regulation
Other_Aur_AURKA_ST	P38398	BRCA1	O14965	AURKA	S1610	P1603T	1603	Missense	distal	-7	no	42.672	40.239	EPSD	COSMIC	39.062	Down-regulation
Other_Aur_AURKA_ST	P38398	BRCA1	O14965	AURKA	S1610	A1608T	1608	Missense	proximal	-2	no	42.672	35.097	EPSD	COSMIC	39.062	Loss
Other_Aur_AURKA_ST	P38398	BRCA1	O14965	AURKA	S1610	Q1612H	1612	Missense	proximal	2	no	42.672	39.567	EPSD	COSMIC	39.062	Down-regulation
Other_Aur_AURKA_ST	P38398	BRCA1	O14965	AURKA	S1610	A1615V	1615	Missense	distal	5	no	42.672	42.055	EPSD	COSMIC	39.062	Down-regulation
Other_Aur_AURKA_ST	P38398	BRCA1	O14965	AURKA	S1610	V1607M	1607	Missense	distal	-3	no	42.672	34.936	EPSD	COSMIC	39.062	Loss
Other_Aur_AURKA_ST	P38398	BRCA1	O14965	AURKA	S1610	V1607E	1607	Missense	distal	-3	no	42.672	38.469	EPSD	COSMIC	39.062	Loss
Other_Aur_AURKA_ST	P38398	BRCA1	O14965	AURKA	T1619	A1615V	1615	Missense	distal	-4	no	35.483	39.158	EPSD	COSMIC	39.062	Gain
Other_Aur_AURKA_ST	P38398	BRCA1	O14965	AURKA	S1651	M1652I	1652	Missense	proximal	1	no	39.077	36.515	EPSD	COSMIC	39.062	Loss
Other_Aur_AURKA_ST	P38398	BRCA1	O14965	AURKA	S1651	R1645T	1645	Missense	distal	-6	no	39.077	38.043	EPSD	COSMIC	39.062	Loss
Other_Aur_AURKA_ST	P38398	BRCA1	O14965	AURKA	S1651	R1645M	1645	Missense	distal	-6	no	39.077	37.571	EPSD	COSMIC	39.062	Loss
Other_Aur_AURKA_ST	P38398	BRCA1	O14965	AURKA	S1651	S1651F	1651	Missense	central	0	yes	39.077	0.000	EPSD	COSMIC	39.062	Loss
Other_Aur_AURKA_ST	P38398	BRCA1	O14965	AURKA	S1651	R1645S	1645	Missense	distal	-6	no	39.077	38.048	EPSD	COSMIC	39.062	Loss
Other_Aur_AURKA_ST	P38398	BRCA1	O14965	AURKA	S1651	R1649T	1649	Missense	proximal	-2	no	39.077	19.864	EPSD	COSMIC	39.062	Loss
Other_Aur_AURKA_ST	P38398	BRCA1	O14965	AURKA	S1651	V1654E	1654	Missense	distal	3	no	39.077	40.364	EPSD	COSMIC	39.062	Up-regulation
Other_Aur_AURKA_ST	P38398	BRCA1	O14965	AURKA	S1651	R1649I	1649	Missense	proximal	-2	no	39.077	20.048	EPSD	COSMIC	39.062	Loss
Other_Aur_AURKA_ST	P38398	BRCA1	O14965	AURKA	S1651	V1653A	1653	Missense	proximal	2	no	39.077	37.645	EPSD	COSMIC	39.062	Loss
Other_Aur_AURKA_ST	P38398	BRCA1	O14965	AURKA	S1651	R1649K	1649	Missense	proximal	-2	no	39.077	32.574	EPSD	COSMIC	39.062	Loss
Other_Aur_AURKA_ST	P38398	BRCA1	O14965	AURKA	S1651	V1654M	1654	Missense	distal	3	no	39.077	40.531	EPSD	COSMIC	39.062	Up-regulation
Other_Aur_AURKA_ST	P12755	SKI	O14965	AURKA	S325	P328H	328	Missense	distal	3	no	51.752	51.073	EPSD	COSMIC	39.062	Down-regulation
Other_Aur_AURKA_ST	P12755	SKI	O14965	AURKA	S325	S326F	326	Missense	proximal	1	no	51.752	58.232	EPSD	COSMIC	39.062	Up-regulation
Other_Aur_AURKA_ST	P12755	SKI	O14965	AURKA	S326	P328H	328	Missense	proximal	2	no	47.043	45.980	EPSD;PhosphoSitePlus	COSMIC	39.062	Down-regulation
Other_Aur_AURKA_ST	P12755	SKI	O14965	AURKA	S326	S326F	326	Missense	central	0	yes	47.043	0.000	EPSD;PhosphoSitePlus	COSMIC	39.062	Loss
Other_Aur_AURKA_ST	P12755	SKI	O14965	AURKA	S347	P352L	352	Missense	distal	5	no	40.452	39.869	EPSD	COSMIC;CCLE	39.062	Down-regulation
Other_Aur_AURKA_ST	P12755	SKI	O14965	AURKA	S347	S354N	354	Missense	distal	7	no	40.452	40.374	EPSD	COSMIC	39.062	Down-regulation
Other_Aur_AURKA_ST	P12755	SKI	O14965	AURKA	S366	R373C	373	Missense	distal	7	no	42.403	42.444	EPSD	COSMIC;CCLE	39.062	Up-regulation
Other_Aur_AURKA_ST	P12755	SKI	O14965	AURKA	S377	R373C	373	Missense	distal	-4	no	40.998	37.797	EPSD	COSMIC;CCLE	39.062	Loss
Other_Aur_AURKA_ST	P12755	SKI	O14965	AURKA	S377	R380Q	380	Missense	distal	3	no	40.998	41.386	EPSD	COSMIC	39.062	Up-regulation
Other_Aur_AURKA_ST	P12755	SKI	O14965	AURKA	S383	A388V	388	Missense	distal	5	no	50.892	50.276	PhosphoSitePlus;EPSD	COSMIC	39.062	Down-regulation
Other_Aur_AURKA_ST	P12755	SKI	O14965	AURKA	S383	A385S	385	Missense	proximal	2	no	50.892	52.776	PhosphoSitePlus;EPSD	COSMIC	39.062	Up-regulation
Other_Aur_AURKA_ST	P12755	SKI	O14965	AURKA	S383	R380Q	380	Missense	distal	-3	no	50.892	41.229	PhosphoSitePlus;EPSD	COSMIC	39.062	Down-regulation
Other_Aur_AURKA_ST	P12755	SKI	O14965	AURKA	S404	L397I	397	Missense	distal	-7	no	42.731	42.020	EPSD	COSMIC;GDSC;CCLE	39.062	Down-regulation
Other_Aur_AURKA_ST	P12755	SKI	O14965	AURKA	S404	R402Q	402	Missense	proximal	-2	no	42.731	32.092	EPSD	COSMIC;GDSC;CCLE	39.062	Loss
Other_Aur_AURKA_ST	P12755	SKI	O14965	AURKA	S404	A399T	399	Missense	distal	-5	no	42.731	42.769	EPSD	COSMIC;GDSC;CCLE	39.062	Up-regulation
Other_Aur_AURKA_ST	P12755	SKI	O14965	AURKA	S498	F492C	492	Missense	distal	-6	no	41.320	40.961	EPSD	COSMIC	39.062	Down-regulation
Other_Aur_AURKA_ST	P12755	SKI	O14965	AURKA	S501	S508R	508	Missense	distal	7	no	40.310	40.292	EPSD	COSMIC	39.062	Down-regulation
Other_Aur_AURKA_ST	P12755	SKI	O14965	AURKA	S509	S508R	508	Missense	proximal	-1	no	41.921	41.910	EPSD	COSMIC	39.062	Down-regulation
Other_Aur_AURKA_ST	P12755	SKI	O14965	AURKA	S509	D512N	512	Missense	distal	3	no	41.921	37.436	EPSD	COSMIC	39.062	Loss
Other_Aur_AURKA_ST	P12755	SKI	O14965	AURKA	S509	S515C	515	Missense	distal	6	no	41.921	41.732	EPSD	COSMIC	39.062	Down-regulation
Other_Aur_AURKA_ST	P12755	SKI	O14965	AURKA	S509	A510P	510	Missense	proximal	1	no	41.921	38.001	EPSD	COSMIC	39.062	Loss
Other_Aur_AURKA_ST	Q9BQG0	MYBBP1A	O14965	AURKA	S672	A670T	670	Missense	proximal	-2	no	46.627	39.052	EPSD	COSMIC;CCLE	39.062	Loss
Other_Aur_AURKA_ST	Q9BQG0	MYBBP1A	O14965	AURKA	S672	V673M	673	Missense	proximal	1	no	46.627	46.626	EPSD	COSMIC	39.062	Down-regulation
Other_Aur_AURKA_ST	Q9BQG0	MYBBP1A	O14965	AURKA	S1166	R1169Q	1169	Missense	distal	3	no	42.800	43.189	EPSD	COSMIC	39.062	Up-regulation
Other_Aur_AURKA_ST	Q9BQG0	MYBBP1A	O14965	AURKA	S1166	K1172R	1172	Missense	distal	6	no	42.800	43.009	EPSD	COSMIC;GDSC;CCLE	39.062	Up-regulation
Other_Aur_AURKA_ST	Q9BQG0	MYBBP1A	O14965	AURKA	S1186	T1190M	1190	Missense	distal	4	no	42.983	44.878	EPSD	COSMIC	39.062	Up-regulation
Other_Aur_AURKA_ST	Q9BQG0	MYBBP1A	O14965	AURKA	S1303	V1305A	1305	Missense	proximal	2	no	51.884	50.452	PhosphoSitePlus	COSMIC	39.062	Down-regulation
Other_Aur_AURKA_ST	Q9BQG0	MYBBP1A	O14965	AURKA	S1303	R1297Q	1297	Missense	distal	-6	no	51.884	51.018	PhosphoSitePlus	COSMIC	39.062	Down-regulation
Other_Aur_AURKA_ST	P49841	GSK3B	O14965	AURKA	S215	Y222C	222	Missense	distal	7	no	40.204	40.147	EPSD	COSMIC	39.062	Down-regulation
Other_Aur_AURKA_ST	P49841	GSK3B	O14965	AURKA	T277	R278M	278	Missense	proximal	1	no	37.897	39.416	EPSD	COSMIC	39.062	Gain
Other_Aur_AURKA_ST	Q9HC77	CENPJ	O14965	AURKA	S405	E408D	408	Missense	distal	3	no	40.458	41.503	EPSD	COSMIC	39.062	Up-regulation
Other_Aur_AURKA_ST	Q9HC77	CENPJ	O14965	AURKA	S529	S534G	534	Missense	distal	5	no	43.885	43.986	EPSD	COSMIC	39.062	Up-regulation
Other_Aur_AURKA_ST	Q9HC77	CENPJ	O14965	AURKA	S529	A533T	533	Missense	distal	4	no	43.885	42.836	EPSD	COSMIC	39.062	Down-regulation
Other_Aur_AURKA_ST	Q9HC77	CENPJ	O14965	AURKA	S529	S534N	534	Missense	distal	5	no	43.885	43.496	EPSD	COSMIC;GDSC;CCLE	39.062	Down-regulation
Other_Aur_AURKA_ST	Q9HC77	CENPJ	O14965	AURKA	S660	L661F	661	Missense	proximal	1	no	39.799	40.630	EPSD	COSMIC;GDSC;CCLE	39.062	Up-regulation
Other_Aur_AURKA_ST	Q9HC77	CENPJ	O14965	AURKA	S717	D720A	720	Missense	distal	3	no	41.443	39.233	EPSD	COSMIC;GDSC;CCLE	39.062	Down-regulation
Other_Aur_AURKA_ST	Q9HC77	CENPJ	O14965	AURKA	S857	P861L	861	Missense	distal	4	no	52.074	52.221	EPSD	COSMIC	39.062	Up-regulation
Other_Aur_AURKA_ST	Q9BT25	HAUS8	O14965	AURKA	S69	S63L	63	Missense	distal	-6	no	41.742	40.212	EPSD	COSMIC	39.062	Down-regulation
Other_Aur_AURKA_ST	Q9BT25	HAUS8	O14965	AURKA	S69	S70A	70	Missense	proximal	1	no	41.742	46.663	EPSD	COSMIC	39.062	Up-regulation
Other_Aur_AURKA_ST	Q9BT25	HAUS8	O14965	AURKA	S69	Q73R	73	Missense	distal	4	no	41.742	41.328	EPSD	COSMIC	39.062	Down-regulation
Other_Aur_AURKA_ST	Q9BT25	HAUS8	O14965	AURKA	S69	S63F	63	Missense	distal	-6	no	41.742	36.084	EPSD	COSMIC	39.062	Loss
Other_Aur_AURKA_ST	Q9BT25	HAUS8	O14965	AURKA	S69	E64K	64	Missense	distal	-5	no	41.742	41.724	EPSD	COSMIC	39.062	Down-regulation
Other_Aur_AURKA_ST	Q9BT25	HAUS8	O14965	AURKA	S70	S63L	63	Missense	distal	-7	no	44.480	44.667	EPSD	COSMIC	39.062	Up-regulation
Other_Aur_AURKA_ST	Q9BT25	HAUS8	O14965	AURKA	S70	S70A	70	Missense	central	0	yes	44.480	0.000	EPSD	COSMIC	39.062	Loss
Other_Aur_AURKA_ST	Q9BT25	HAUS8	O14965	AURKA	S70	Q73R	73	Missense	distal	3	no	44.480	44.091	EPSD	COSMIC	39.062	Down-regulation
Other_Aur_AURKA_ST	Q9BT25	HAUS8	O14965	AURKA	S70	S63F	63	Missense	distal	-7	no	44.480	44.311	EPSD	COSMIC	39.062	Down-regulation
Other_Aur_AURKA_ST	Q9BT25	HAUS8	O14965	AURKA	S70	E64K	64	Missense	distal	-6	no	44.480	45.663	EPSD	COSMIC	39.062	Up-regulation
Other_Aur_AURKA_ST	Q9BT25	HAUS8	O14965	AURKA	T97	G96D	96	Missense	proximal	-1	no	43.808	45.070	EPSD	COSMIC	39.062	Up-regulation
Other_Aur_AURKA_ST	Q9BT25	HAUS8	O14965	AURKA	T97	L104I	104	Missense	distal	7	no	43.808	43.946	EPSD	COSMIC	39.062	Up-regulation
Other_Aur_AURKA_ST	P40337	VHL	O14965	AURKA	S33	E31G	31	Missense	proximal	-2	no	28.787	39.290	EPSD	COSMIC	39.062	Gain
Other_Aur_AURKA_ST	P40337	VHL	O14965	AURKA	S72	N78T	78	Missense	distal	6	no	46.918	47.078	PhosphoSitePlus	COSMIC;CCLE	39.062	Up-regulation
Other_Aur_AURKA_ST	P40337	VHL	O14965	AURKA	S72	S65T	65	Missense	distal	-7	no	46.918	46.344	PhosphoSitePlus	COSMIC	39.062	Down-regulation
Other_Aur_AURKA_ST	P40337	VHL	O14965	AURKA	S72	S68T	68	Missense	distal	-4	no	46.918	48.914	PhosphoSitePlus	COSMIC	39.062	Up-regulation
Other_Aur_AURKA_ST	P40337	VHL	O14965	AURKA	S72	F76Y	76	Missense	distal	4	no	46.918	46.186	PhosphoSitePlus	COSMIC	39.062	Down-regulation
Other_Aur_AURKA_ST	P40337	VHL	O14965	AURKA	S72	Q73H	73	Missense	proximal	1	no	46.918	44.038	PhosphoSitePlus	COSMIC	39.062	Down-regulation
Other_Aur_AURKA_ST	P40337	VHL	O14965	AURKA	S72	P71T	71	Missense	proximal	-1	no	46.918	48.834	PhosphoSitePlus	COSMIC	39.062	Up-regulation
Other_Aur_AURKA_ST	P40337	VHL	O14965	AURKA	S72	F76S	76	Missense	distal	4	no	46.918	46.435	PhosphoSitePlus	COSMIC	39.062	Down-regulation
Other_Aur_AURKA_ST	P40337	VHL	O14965	AURKA	S72	F76L	76	Missense	distal	4	no	46.918	46.528	PhosphoSitePlus	COSMIC	39.062	Down-regulation
Other_Aur_AURKA_ST	P40337	VHL	O14965	AURKA	S72	S65Q	65	Missense	distal	-7	no	46.918	46.969	PhosphoSitePlus	COSMIC	39.062	Up-regulation
Other_Aur_AURKA_ST	P40337	VHL	O14965	AURKA	S72	S65A	65	Missense	distal	-7	no	46.918	46.802	PhosphoSitePlus	COSMIC	39.062	Down-regulation
Other_Aur_AURKA_ST	P40337	VHL	O14965	AURKA	S72	C77S	77	Missense	distal	5	no	46.918	45.920	PhosphoSitePlus	COSMIC	39.062	Down-regulation
Other_Aur_AURKA_ST	P40337	VHL	O14965	AURKA	S72	S72P	72	Missense	central	0	yes	46.918	0.000	PhosphoSitePlus	COSMIC	39.062	Loss
Other_Aur_AURKA_ST	P40337	VHL	O14965	AURKA	S72	S68P	68	Missense	distal	-4	no	46.918	45.000	PhosphoSitePlus	COSMIC	39.062	Down-regulation
Other_Aur_AURKA_ST	P40337	VHL	O14965	AURKA	S72	Q73K	73	Missense	proximal	1	no	46.918	46.692	PhosphoSitePlus	COSMIC	39.062	Down-regulation
Other_Aur_AURKA_ST	P40337	VHL	O14965	AURKA	S72	N67S	67	Missense	distal	-5	no	46.918	46.869	PhosphoSitePlus	COSMIC	39.062	Down-regulation
Other_Aur_AURKA_ST	P40337	VHL	O14965	AURKA	S72	I75V	75	Missense	distal	3	no	46.918	44.909	PhosphoSitePlus	COSMIC	39.062	Down-regulation
Other_Aur_AURKA_ST	P40337	VHL	O14965	AURKA	S72	N78H	78	Missense	distal	6	no	46.918	47.160	PhosphoSitePlus	COSMIC	39.062	Up-regulation
Other_Aur_AURKA_ST	P40337	VHL	O14965	AURKA	S72	S68L	68	Missense	distal	-4	no	46.918	46.152	PhosphoSitePlus	COSMIC	39.062	Down-regulation
Other_Aur_AURKA_ST	P40337	VHL	O14965	AURKA	S72	R69C	69	Missense	distal	-3	no	46.918	42.381	PhosphoSitePlus	COSMIC	39.062	Down-regulation
Other_Aur_AURKA_ST	P40337	VHL	O14965	AURKA	S111	R107C	107	Missense	distal	-4	no	44.644	41.443	EPSD	COSMIC	39.062	Down-regulation
Other_Aur_AURKA_ST	P40337	VHL	O14965	AURKA	S111	G114A	114	Missense	distal	3	no	44.644	43.595	EPSD	COSMIC	39.062	Down-regulation
Other_Aur_AURKA_ST	P40337	VHL	O14965	AURKA	S111	H115P	115	Missense	distal	4	no	44.644	44.452	EPSD	COSMIC	39.062	Down-regulation
Other_Aur_AURKA_ST	P40337	VHL	O14965	AURKA	S111	G106D	106	Missense	distal	-5	no	44.644	44.676	EPSD	COSMIC	39.062	Up-regulation
Other_Aur_AURKA_ST	P40337	VHL	O14965	AURKA	S111	H110Y	110	Missense	proximal	-1	no	44.644	44.120	EPSD	COSMIC	39.062	Down-regulation
Other_Aur_AURKA_ST	P40337	VHL	O14965	AURKA	S111	W117R	117	Missense	distal	6	no	44.644	44.434	EPSD	COSMIC	39.062	Down-regulation
Other_Aur_AURKA_ST	P40337	VHL	O14965	AURKA	S111	H110Q	110	Missense	proximal	-1	no	44.644	44.713	EPSD	COSMIC	39.062	Up-regulation
Other_Aur_AURKA_ST	P40337	VHL	O14965	AURKA	S111	H110N	110	Missense	proximal	-1	no	44.644	43.225	EPSD	COSMIC	39.062	Down-regulation
Other_Aur_AURKA_ST	P40337	VHL	O14965	AURKA	S111	G114C	114	Missense	distal	3	no	44.644	42.712	EPSD	COSMIC	39.062	Down-regulation
Other_Aur_AURKA_ST	P40337	VHL	O14965	AURKA	S111	G114S	114	Missense	distal	3	no	44.644	45.050	EPSD	COSMIC	39.062	Up-regulation
Other_Aur_AURKA_ST	P40337	VHL	O14965	AURKA	S111	Y112D	112	Missense	proximal	1	no	44.644	44.643	EPSD	COSMIC	39.062	Down-regulation
Other_Aur_AURKA_ST	P40337	VHL	O14965	AURKA	S111	I109S	109	Missense	proximal	-2	no	44.644	50.514	EPSD	COSMIC	39.062	Up-regulation
Other_Aur_AURKA_ST	P40337	VHL	O14965	AURKA	S111	H110R	110	Missense	proximal	-1	no	44.644	45.053	EPSD	COSMIC	39.062	Up-regulation
Other_Aur_AURKA_ST	P40337	VHL	O14965	AURKA	S111	L116V	116	Missense	distal	5	no	44.644	44.972	EPSD	COSMIC	39.062	Up-regulation
Other_Aur_AURKA_ST	P40337	VHL	O14965	AURKA	S111	G114R	114	Missense	distal	3	no	44.644	43.985	EPSD	COSMIC	39.062	Down-regulation
Other_Aur_AURKA_ST	P40337	VHL	O14965	AURKA	S111	G114V	114	Missense	distal	3	no	44.644	43.473	EPSD	COSMIC	39.062	Down-regulation
Other_Aur_AURKA_ST	P40337	VHL	O14965	AURKA	S111	T105M	105	Missense	distal	-6	no	44.644	44.172	EPSD	COSMIC	39.062	Down-regulation
Other_Aur_AURKA_ST	P40337	VHL	O14965	AURKA	S111	I109F	109	Missense	proximal	-2	no	44.644	45.263	EPSD	COSMIC	39.062	Up-regulation
Other_Aur_AURKA_ST	P40337	VHL	O14965	AURKA	S111	G106A	106	Missense	distal	-5	no	44.644	44.630	EPSD	COSMIC	39.062	Down-regulation
Other_Aur_AURKA_ST	P40337	VHL	O14965	AURKA	S111	H115L	115	Missense	distal	4	no	44.644	44.599	EPSD	COSMIC	39.062	Down-regulation
Other_Aur_AURKA_ST	P40337	VHL	O14965	AURKA	S111	T105K	105	Missense	distal	-6	no	44.644	42.694	EPSD	COSMIC	39.062	Down-regulation
Other_Aur_AURKA_ST	P40337	VHL	O14965	AURKA	S111	T105P	105	Missense	distal	-6	no	44.644	44.099	EPSD	COSMIC	39.062	Down-regulation
Other_Aur_AURKA_ST	P40337	VHL	O14965	AURKA	S111	G114D	114	Missense	distal	3	no	44.644	45.805	EPSD	COSMIC	39.062	Up-regulation
Other_Aur_AURKA_ST	P40337	VHL	O14965	AURKA	S111	L118H	118	Missense	distal	7	no	44.644	44.657	EPSD	COSMIC	39.062	Up-regulation
Other_Aur_AURKA_ST	P40337	VHL	O14965	AURKA	S111	W117S	117	Missense	distal	6	no	44.644	44.452	EPSD	COSMIC	39.062	Down-regulation
Other_Aur_AURKA_ST	P40337	VHL	O14965	AURKA	S111	G106V	106	Missense	distal	-5	no	44.644	44.655	EPSD	COSMIC	39.062	Up-regulation
Other_Aur_AURKA_ST	P40337	VHL	O14965	AURKA	S111	H115D	115	Missense	distal	4	no	44.644	44.713	EPSD	COSMIC	39.062	Up-regulation
Other_Aur_AURKA_ST	P40337	VHL	O14965	AURKA	S111	L118R	118	Missense	distal	7	no	44.644	44.652	EPSD	COSMIC	39.062	Up-regulation
Other_Aur_AURKA_ST	P40337	VHL	O14965	AURKA	S111	R107G	107	Missense	distal	-4	no	44.644	44.325	EPSD	COSMIC	39.062	Down-regulation
Other_Aur_AURKA_ST	P40337	VHL	O14965	AURKA	S111	S111P	111	Missense	central	0	yes	44.644	0.000	EPSD	COSMIC	39.062	Loss
Other_Aur_AURKA_ST	P40337	VHL	O14965	AURKA	S168	V166F	166	Missense	proximal	-2	no	46.126	38.756	EPSD	COSMIC	39.062	Loss
Other_Aur_AURKA_ST	P40337	VHL	O14965	AURKA	S168	C162W	162	Missense	distal	-6	no	46.126	39.023	EPSD	COSMIC	39.062	Loss
Other_Aur_AURKA_ST	P40337	VHL	O14965	AURKA	S168	K171N	171	Missense	distal	3	no	46.126	44.081	EPSD	COSMIC	39.062	Down-regulation
Other_Aur_AURKA_ST	P40337	VHL	O14965	AURKA	S168	L163P	163	Missense	distal	-5	no	46.126	46.114	EPSD	COSMIC	39.062	Down-regulation
Other_Aur_AURKA_ST	P40337	VHL	O14965	AURKA	S168	R167Q	167	Missense	proximal	-1	no	46.126	45.786	EPSD	COSMIC	39.062	Down-regulation
Other_Aur_AURKA_ST	P40337	VHL	O14965	AURKA	S168	Q164R	164	Missense	distal	-4	no	46.126	45.973	EPSD	COSMIC	39.062	Down-regulation
Other_Aur_AURKA_ST	P40337	VHL	O14965	AURKA	S168	V166D	166	Missense	proximal	-2	no	46.126	48.504	EPSD	COSMIC	39.062	Up-regulation
Other_Aur_AURKA_ST	P40337	VHL	O14965	AURKA	S168	V166G	166	Missense	proximal	-2	no	46.126	47.022	EPSD	COSMIC	39.062	Up-regulation
Other_Aur_AURKA_ST	P40337	VHL	O14965	AURKA	S168	Y175D	175	Missense	distal	7	no	46.126	46.118	EPSD	COSMIC	39.062	Down-regulation
Other_Aur_AURKA_ST	P40337	VHL	O14965	AURKA	S168	R161G	161	Missense	distal	-7	no	46.126	44.239	EPSD	COSMIC	39.062	Down-regulation
Other_Aur_AURKA_ST	P40337	VHL	O14965	AURKA	S168	Q164P	164	Missense	distal	-4	no	46.126	44.857	EPSD	COSMIC	39.062	Down-regulation
Other_Aur_AURKA_ST	P40337	VHL	O14965	AURKA	S168	C162Y	162	Missense	distal	-6	no	46.126	50.261	EPSD	COSMIC	39.062	Up-regulation
Other_Aur_AURKA_ST	P40337	VHL	O14965	AURKA	S168	L163H	163	Missense	distal	-5	no	46.126	46.083	EPSD	COSMIC	39.062	Down-regulation
Other_Aur_AURKA_ST	P40337	VHL	O14965	AURKA	S168	V170D	170	Missense	proximal	2	no	46.126	47.803	EPSD	COSMIC	39.062	Up-regulation
Other_Aur_AURKA_ST	P40337	VHL	O14965	AURKA	S168	P172T	172	Missense	distal	4	no	46.126	45.164	EPSD	COSMIC	39.062	Down-regulation
Other_Aur_AURKA_ST	P40337	VHL	O14965	AURKA	S168	V165I	165	Missense	distal	-3	no	46.126	43.018	EPSD	COSMIC	39.062	Down-regulation
Other_Aur_AURKA_ST	P40337	VHL	O14965	AURKA	S168	R161L	161	Missense	distal	-7	no	46.126	45.740	EPSD	COSMIC	39.062	Down-regulation
Other_Aur_AURKA_ST	P40337	VHL	O14965	AURKA	S168	V170A	170	Missense	proximal	2	no	46.126	44.694	EPSD	COSMIC	39.062	Down-regulation
Other_Aur_AURKA_ST	P40337	VHL	O14965	AURKA	S168	V165L	165	Missense	distal	-3	no	46.126	43.773	EPSD	COSMIC	39.062	Down-regulation
Other_Aur_AURKA_ST	P40337	VHL	O14965	AURKA	S168	Q164L	164	Missense	distal	-4	no	46.126	46.008	EPSD	COSMIC	39.062	Down-regulation
Other_Aur_AURKA_ST	P40337	VHL	O14965	AURKA	S168	E173Q	173	Missense	distal	5	no	46.126	47.347	EPSD	COSMIC	39.062	Up-regulation
Other_Aur_AURKA_ST	P40337	VHL	O14965	AURKA	S168	Q164H	164	Missense	distal	-4	no	46.126	41.538	EPSD	COSMIC	39.062	Down-regulation
Other_Aur_AURKA_ST	P40337	VHL	O14965	AURKA	S168	V166I	166	Missense	proximal	-2	no	46.126	38.137	EPSD	COSMIC	39.062	Loss
Other_Aur_AURKA_ST	P40337	VHL	O14965	AURKA	S168	S168C	168	Missense	central	0	yes	46.126	0.000	EPSD	COSMIC	39.062	Loss
Other_Aur_AURKA_ST	P40337	VHL	O14965	AURKA	S168	L163R	163	Missense	distal	-5	no	46.126	46.139	EPSD	COSMIC	39.062	Up-regulation
Other_Aur_AURKA_ST	P40337	VHL	O14965	AURKA	S168	N174D	174	Missense	distal	6	no	46.126	46.533	EPSD	COSMIC	39.062	Up-regulation
Other_Aur_AURKA_ST	P40337	VHL	O14965	AURKA	S168	L169Q	169	Missense	proximal	1	no	46.126	44.587	EPSD	COSMIC	39.062	Down-regulation
Other_Aur_AURKA_ST	P40337	VHL	O14965	AURKA	S168	L163F	163	Missense	distal	-5	no	46.126	46.141	EPSD	COSMIC	39.062	Up-regulation
Other_Aur_AURKA_ST	P40337	VHL	O14965	AURKA	S168	P172S	172	Missense	distal	4	no	46.126	46.180	EPSD	COSMIC	39.062	Up-regulation
Other_Aur_AURKA_ST	P40337	VHL	O14965	AURKA	S183	D187V	187	Missense	distal	4	no	46.047	45.579	EPSD	COSMIC	39.062	Down-regulation
Other_Aur_AURKA_ST	P40337	VHL	O14965	AURKA	S183	E186K	186	Missense	distal	3	no	46.047	44.651	EPSD	COSMIC	39.062	Down-regulation
Other_Aur_AURKA_ST	P40337	VHL	O14965	AURKA	S183	L188V	188	Missense	distal	5	no	46.047	46.375	EPSD	COSMIC	39.062	Up-regulation
Other_Aur_AURKA_ST	P40337	VHL	O14965	AURKA	S183	E189K	189	Missense	distal	6	no	46.047	45.881	EPSD	COSMIC	39.062	Down-regulation
Other_Aur_AURKA_ST	P40337	VHL	O14965	AURKA	S183	L184R	184	Missense	proximal	1	no	46.047	43.617	EPSD	COSMIC	39.062	Down-regulation
Other_Aur_AURKA_ST	P40337	VHL	O14965	AURKA	S183	I180V	180	Missense	distal	-3	no	46.047	49.155	EPSD	COSMIC	39.062	Up-regulation
Other_Aur_AURKA_ST	P40337	VHL	O14965	AURKA	S183	E189V	189	Missense	distal	6	no	46.047	46.018	EPSD	COSMIC	39.062	Down-regulation
Other_Aur_AURKA_ST	P40337	VHL	O14965	AURKA	S183	Y185F	185	Missense	proximal	2	no	46.047	44.110	EPSD	COSMIC	39.062	Down-regulation
Other_Aur_AURKA_ST	P40337	VHL	O14965	AURKA	S183	D187N	187	Missense	distal	4	no	46.047	44.965	EPSD	COSMIC	39.062	Down-regulation
Other_Aur_AURKA_ST	P40337	VHL	O14965	AURKA	S183	S183L	183	Missense	central	0	yes	46.047	0.000	EPSD	COSMIC	39.062	Loss
Other_Aur_AURKA_ST	P40337	VHL	O14965	AURKA	S183	V181I	181	Missense	proximal	-2	no	46.047	38.058	EPSD	COSMIC	39.062	Loss
Other_Aur_AURKA_ST	P40337	VHL	O14965	AURKA	S183	L184H	184	Missense	proximal	1	no	46.047	41.629	EPSD	COSMIC	39.062	Down-regulation
Other_Aur_AURKA_ST	P40337	VHL	O14965	AURKA	S183	I180N	180	Missense	distal	-3	no	46.047	48.482	EPSD	COSMIC;GDSC;CCLE	39.062	Up-regulation
Other_Aur_AURKA_ST	P40337	VHL	O14965	AURKA	S183	L178R	178	Missense	distal	-5	no	46.047	46.060	EPSD	COSMIC	39.062	Up-regulation
Other_Aur_AURKA_ST	P40337	VHL	O14965	AURKA	S183	L188Q	188	Missense	distal	5	no	46.047	48.520	EPSD	COSMIC	39.062	Up-regulation
Other_Aur_AURKA_ST	P40337	VHL	O14965	AURKA	S183	R176W	176	Missense	distal	-7	no	46.047	42.747	EPSD	COSMIC	39.062	Down-regulation
Other_Aur_AURKA_ST	P40337	VHL	O14965	AURKA	S183	R182M	182	Missense	proximal	-1	no	46.047	46.177	EPSD	COSMIC	39.062	Up-regulation
Other_Aur_AURKA_ST	P40337	VHL	O14965	AURKA	S183	L178M	178	Missense	distal	-5	no	46.047	46.074	EPSD	COSMIC	39.062	Up-regulation
Other_Aur_AURKA_ST	P40337	VHL	O14965	AURKA	S183	R182K	182	Missense	proximal	-1	no	46.047	45.699	EPSD	COSMIC	39.062	Down-regulation
Other_Aur_AURKA_ST	P40337	VHL	O14965	AURKA	S183	D179A	179	Missense	distal	-4	no	46.047	46.591	EPSD	COSMIC	39.062	Up-regulation
Other_Aur_AURKA_ST	P40337	VHL	O14965	AURKA	S183	D179N	179	Missense	distal	-4	no	46.047	50.103	EPSD	COSMIC	39.062	Up-regulation
Other_Aur_AURKA_ST	P40337	VHL	O14965	AURKA	S183	E189Q	189	Missense	distal	6	no	46.047	46.046	EPSD	COSMIC	39.062	Down-regulation
Other_Aur_AURKA_ST	P40337	VHL	O14965	AURKA	S183	R176K	176	Missense	distal	-7	no	46.047	45.107	EPSD	COSMIC	39.062	Down-regulation
Other_Aur_AURKA_ST	P53671	LIMK2	O14965	AURKA	S166	S168F	168	Missense	proximal	2	no	45.000	44.304	EPSD	COSMIC	39.062	Down-regulation
Other_Aur_AURKA_ST	P53671	LIMK2	O14965	AURKA	S166	R163Q	163	Missense	distal	-3	no	45.000	35.336	EPSD	COSMIC	39.062	Loss
Other_Aur_AURKA_ST	P53671	LIMK2	O14965	AURKA	S283	R286C	286	Missense	distal	3	no	47.999	46.726	EPSD;PhosphoSitePlus	COSMIC	39.062	Down-regulation
Other_Aur_AURKA_ST	P53671	LIMK2	O14965	AURKA	S283	R282C	282	Missense	proximal	-1	no	47.999	47.782	EPSD;PhosphoSitePlus	COSMIC	39.062	Down-regulation
Other_Aur_AURKA_ST	P53671	LIMK2	O14965	AURKA	S283	R286H	286	Missense	distal	3	no	47.999	47.732	EPSD;PhosphoSitePlus	COSMIC;CCLE	39.062	Down-regulation
Other_Aur_AURKA_ST	P53671	LIMK2	O14965	AURKA	S283	T278R	278	Missense	distal	-5	no	47.999	47.994	EPSD;PhosphoSitePlus	COSMIC	39.062	Down-regulation
Other_Aur_AURKA_ST	P53671	LIMK2	O14965	AURKA	S283	R280M	280	Missense	distal	-3	no	47.999	35.101	EPSD;PhosphoSitePlus	COSMIC	39.062	Loss
Other_Aur_AURKA_ST	P53671	LIMK2	O14965	AURKA	S283	S283F	283	Missense	central	0	yes	47.999	0.000	EPSD;PhosphoSitePlus	COSMIC	39.062	Loss
Other_Aur_AURKA_ST	P53671	LIMK2	O14965	AURKA	S283	S289R	289	Missense	distal	6	no	47.999	47.980	EPSD;PhosphoSitePlus	COSMIC	39.062	Down-regulation
Other_Aur_AURKA_ST	P53671	LIMK2	O14965	AURKA	S283	R286Q	286	Missense	distal	3	no	47.999	48.387	EPSD;PhosphoSitePlus	COSMIC	39.062	Up-regulation
Other_Aur_AURKA_ST	P53671	LIMK2	O14965	AURKA	S289	S291F	291	Missense	proximal	2	no	41.508	40.812	EPSD	COSMIC	39.062	Down-regulation
Other_Aur_AURKA_ST	P53671	LIMK2	O14965	AURKA	S289	R286C	286	Missense	distal	-3	no	41.508	36.971	EPSD	COSMIC	39.062	Loss
Other_Aur_AURKA_ST	P53671	LIMK2	O14965	AURKA	S289	R282C	282	Missense	distal	-7	no	41.508	40.301	EPSD	COSMIC	39.062	Down-regulation
Other_Aur_AURKA_ST	P53671	LIMK2	O14965	AURKA	S289	R286H	286	Missense	distal	-3	no	41.508	35.735	EPSD	COSMIC;CCLE	39.062	Loss
Other_Aur_AURKA_ST	P53671	LIMK2	O14965	AURKA	S289	G295D	295	Missense	distal	6	no	41.508	41.659	EPSD	COSMIC	39.062	Up-regulation
Other_Aur_AURKA_ST	P53671	LIMK2	O14965	AURKA	S289	S283F	283	Missense	distal	-6	no	41.508	35.849	EPSD	COSMIC	39.062	Loss
Other_Aur_AURKA_ST	P53671	LIMK2	O14965	AURKA	S289	S289R	289	Missense	central	0	yes	41.508	0.000	EPSD	COSMIC	39.062	Loss
Other_Aur_AURKA_ST	P53671	LIMK2	O14965	AURKA	S289	R286Q	286	Missense	distal	-3	no	41.508	31.844	EPSD	COSMIC	39.062	Loss
Other_Aur_AURKA_ST	P53671	LIMK2	O14965	AURKA	S291	S289R	289	Missense	proximal	-2	no	27.463	40.622	EPSD	COSMIC	39.062	Gain
Other_Aur_AURKA_ST	P53671	LIMK2	O14965	AURKA	S310	R311L	311	Missense	proximal	1	no	46.753	49.183	EPSD	COSMIC	39.062	Up-regulation
Other_Aur_AURKA_ST	P53671	LIMK2	O14965	AURKA	S310	R316C	316	Missense	distal	6	no	46.753	46.583	EPSD	COSMIC;CCLE	39.062	Down-regulation
Other_Aur_AURKA_ST	P53671	LIMK2	O14965	AURKA	S310	S310R	310	Missense	central	0	yes	46.753	0.000	EPSD	COSMIC	39.062	Loss
Other_Aur_AURKA_ST	P53671	LIMK2	O14965	AURKA	S319	R316C	316	Missense	distal	-3	no	39.346	34.809	EPSD	COSMIC;CCLE	39.062	Loss
Other_Aur_AURKA_ST	P53671	LIMK2	O14965	AURKA	S319	I325M	325	Missense	distal	6	no	39.346	39.344	EPSD	COSMIC	39.062	Down-regulation
Other_Aur_AURKA_ST	P53671	LIMK2	O14965	AURKA	S322	C329S	329	Missense	distal	7	no	41.378	41.355	EPSD	COSMIC	39.062	Down-regulation
Other_Aur_AURKA_ST	P53671	LIMK2	O14965	AURKA	S322	R327Q	327	Missense	distal	5	no	41.378	43.758	EPSD	COSMIC	39.062	Up-regulation
Other_Aur_AURKA_ST	P53671	LIMK2	O14965	AURKA	S322	R316C	316	Missense	distal	-6	no	41.378	34.330	EPSD	COSMIC;CCLE	39.062	Loss
Other_Aur_AURKA_ST	P53671	LIMK2	O14965	AURKA	S322	R327W	327	Missense	distal	5	no	41.378	42.377	EPSD	COSMIC	39.062	Up-regulation
Other_Aur_AURKA_ST	P53671	LIMK2	O14965	AURKA	S322	I325M	325	Missense	distal	3	no	41.378	40.824	EPSD	COSMIC	39.062	Down-regulation
Other_Aur_AURKA_ST	P53671	LIMK2	O14965	AURKA	T494	R493H	493	Missense	proximal	-1	no	44.792	44.383	PhosphoSitePlus;EPSD	COSMIC	39.062	Down-regulation
Other_Aur_AURKA_ST	P53671	LIMK2	O14965	AURKA	T494	R496H	496	Missense	proximal	2	no	44.792	43.688	PhosphoSitePlus;EPSD	COSMIC;CCLE	39.062	Down-regulation
Other_Aur_AURKA_ST	P53671	LIMK2	O14965	AURKA	T494	K491N	491	Missense	distal	-3	no	44.792	46.783	PhosphoSitePlus;EPSD	COSMIC	39.062	Up-regulation
Other_Aur_AURKA_ST	P53671	LIMK2	O14965	AURKA	T505	P510H	510	Missense	distal	5	no	45.859	45.877	EPSD;PhosphoSitePlus	COSMIC	39.062	Up-regulation
Other_Aur_AURKA_ST	P53671	LIMK2	O14965	AURKA	T505	R503C	503	Missense	proximal	-2	no	45.859	30.562	EPSD;PhosphoSitePlus	COSMIC	39.062	Loss
Other_Aur_AURKA_ST	Q8TEW0	PARD3	O14965	AURKA	S143	I149T	149	Missense	distal	6	no	44.529	44.361	EPSD	COSMIC	39.062	Down-regulation
Other_Aur_AURKA_ST	Q8TEW0	PARD3	O14965	AURKA	S143	R142H	142	Missense	proximal	-1	no	44.529	44.120	EPSD	COSMIC	39.062	Down-regulation
Other_Aur_AURKA_ST	Q8TEW0	PARD3	O14965	AURKA	S143	A147T	147	Missense	distal	4	no	44.529	43.481	EPSD	COSMIC	39.062	Down-regulation
Other_Aur_AURKA_ST	Q8TEW0	PARD3	O14965	AURKA	S144	I149T	149	Missense	distal	5	no	55.088	54.578	EPSD	COSMIC	39.062	Down-regulation
Other_Aur_AURKA_ST	Q8TEW0	PARD3	O14965	AURKA	S144	R142H	142	Missense	proximal	-2	no	55.088	47.850	EPSD	COSMIC	39.062	Down-regulation
Other_Aur_AURKA_ST	Q8TEW0	PARD3	O14965	AURKA	S144	A147T	147	Missense	distal	3	no	55.088	53.957	EPSD	COSMIC	39.062	Down-regulation
Other_Aur_AURKA_ST	Q8TEW0	PARD3	O14965	AURKA	S174	F179L	179	Missense	distal	5	no	44.902	42.945	EPSD	COSMIC	39.062	Down-regulation
Other_Aur_AURKA_ST	Q8TEW0	PARD3	O14965	AURKA	S174	G178R	178	Missense	distal	4	no	44.902	44.092	EPSD	COSMIC	39.062	Down-regulation
Other_Aur_AURKA_ST	Q8TEW0	PARD3	O14965	AURKA	S223	M228I	228	Missense	distal	5	no	37.957	40.626	EPSD	COSMIC	39.062	Gain
Other_Aur_AURKA_ST	Q8TEW0	PARD3	O14965	AURKA	T401	G398E	398	Missense	distal	-3	no	39.537	35.366	EPSD	COSMIC	39.062	Loss
Other_Aur_AURKA_ST	Q8TEW0	PARD3	O14965	AURKA	S485	S485L	485	Missense	central	0	yes	41.134	0.000	EPSD	COSMIC	39.062	Loss
Other_Aur_AURKA_ST	Q8TEW0	PARD3	O14965	AURKA	S485	N492K	492	Missense	distal	7	no	41.134	41.151	EPSD	COSMIC	39.062	Up-regulation
Other_Aur_AURKA_ST	Q8TEW0	PARD3	O14965	AURKA	S533	S533N	533	Missense	central	0	yes	40.374	0.000	EPSD	COSMIC	39.062	Loss
Other_Aur_AURKA_ST	Q8TEW0	PARD3	O14965	AURKA	S598	V591D	591	Missense	distal	-7	no	40.677	40.387	EPSD	COSMIC	39.062	Down-regulation
Other_Aur_AURKA_ST	Q8TEW0	PARD3	O14965	AURKA	S665	G670S	670	Missense	distal	5	no	42.295	42.194	EPSD	COSMIC	39.062	Down-regulation
Other_Aur_AURKA_ST	Q8TEW0	PARD3	O14965	AURKA	S715	S720T	720	Missense	distal	5	no	46.088	46.418	EPSD	COSMIC	39.062	Up-regulation
Other_Aur_AURKA_ST	Q8TEW0	PARD3	O14965	AURKA	T833	S829T	829	Missense	distal	-4	no	45.157	47.153	EPSD	COSMIC	39.062	Up-regulation
Other_Aur_AURKA_ST	Q8TEW0	PARD3	O14965	AURKA	T833	R832C	832	Missense	proximal	-1	no	45.157	44.940	EPSD	COSMIC	39.062	Down-regulation
Other_Aur_AURKA_ST	Q8TEW0	PARD3	O14965	AURKA	T833	M828L	828	Missense	distal	-5	no	45.157	45.129	EPSD	COSMIC	39.062	Down-regulation
Other_Aur_AURKA_ST	Q8TEW0	PARD3	O14965	AURKA	T833	T833A	833	Missense	central	0	yes	45.157	0.000	EPSD	COSMIC	39.062	Loss
Other_Aur_AURKA_ST	Q8TEW0	PARD3	O14965	AURKA	S850	T847K	847	Missense	distal	-3	no	45.306	47.096	EPSD	COSMIC	39.062	Up-regulation
Other_Aur_AURKA_ST	Q8TEW0	PARD3	O14965	AURKA	S850	V845I	845	Missense	distal	-5	no	45.306	45.309	EPSD	COSMIC	39.062	Up-regulation
Other_Aur_AURKA_ST	Q8TEW0	PARD3	O14965	AURKA	S850	V845L	845	Missense	distal	-5	no	45.306	45.302	EPSD	COSMIC	39.062	Down-regulation
Other_Aur_AURKA_ST	Q8TEW0	PARD3	O14965	AURKA	S873	P874F	874	Missense	proximal	1	no	36.357	41.837	EPSD	COSMIC	39.062	Gain
Other_Aur_AURKA_ST	Q8TEW0	PARD3	O14965	AURKA	S881	G883C	883	Missense	proximal	2	no	43.757	45.539	EPSD	COSMIC	39.062	Up-regulation
Other_Aur_AURKA_ST	Q8TEW0	PARD3	O14965	AURKA	S881	P880A	880	Missense	proximal	-1	no	43.757	44.083	EPSD	COSMIC	39.062	Up-regulation
Other_Aur_AURKA_ST	Q8TEW0	PARD3	O14965	AURKA	S881	K885Q	885	Missense	distal	4	no	43.757	43.195	EPSD	COSMIC	39.062	Down-regulation
Other_Aur_AURKA_ST	Q8TEW0	PARD3	O14965	AURKA	S881	P874F	874	Missense	distal	-7	no	43.757	41.728	EPSD	COSMIC	39.062	Down-regulation
Other_Aur_AURKA_ST	Q8TEW0	PARD3	O14965	AURKA	S881	S887F	887	Missense	distal	6	no	43.757	43.902	EPSD	COSMIC	39.062	Up-regulation
Other_Aur_AURKA_ST	Q8TEW0	PARD3	O14965	AURKA	S888	G883C	883	Missense	distal	-5	no	40.545	40.688	EPSD	COSMIC	39.062	Up-regulation
Other_Aur_AURKA_ST	Q8TEW0	PARD3	O14965	AURKA	S888	K885Q	885	Missense	distal	-3	no	40.545	38.707	EPSD	COSMIC	39.062	Loss
Other_Aur_AURKA_ST	Q8TEW0	PARD3	O14965	AURKA	S888	Q894K	894	Missense	distal	6	no	40.545	40.380	EPSD	COSMIC	39.062	Down-regulation
Other_Aur_AURKA_ST	Q8TEW0	PARD3	O14965	AURKA	S888	S892G	892	Missense	distal	4	no	40.545	40.823	EPSD	COSMIC	39.062	Up-regulation
Other_Aur_AURKA_ST	Q8TEW0	PARD3	O14965	AURKA	S888	S887F	887	Missense	proximal	-1	no	40.545	41.617	EPSD	COSMIC	39.062	Up-regulation
Other_Aur_AURKA_ST	Q8TEW0	PARD3	O14965	AURKA	S892	K885Q	885	Missense	distal	-7	no	40.397	40.814	EPSD	COSMIC	39.062	Up-regulation
Other_Aur_AURKA_ST	Q8TEW0	PARD3	O14965	AURKA	S892	Q894K	894	Missense	proximal	2	no	40.397	36.993	EPSD	COSMIC	39.062	Loss
Other_Aur_AURKA_ST	Q8TEW0	PARD3	O14965	AURKA	S892	S892G	892	Missense	central	0	yes	40.397	0.000	EPSD	COSMIC	39.062	Loss
Other_Aur_AURKA_ST	Q8TEW0	PARD3	O14965	AURKA	S892	S887F	887	Missense	distal	-5	no	40.397	40.404	EPSD	COSMIC	39.062	Up-regulation
Other_Aur_AURKA_ST	Q8TEW0	PARD3	O14965	AURKA	S962	G959D	959	Missense	distal	-3	no	46.913	41.616	PhosphoSitePlus	COSMIC	39.062	Down-regulation
Other_Aur_AURKA_ST	Q8TEW0	PARD3	O14965	AURKA	S962	S964G	964	Missense	proximal	2	no	46.913	47.079	PhosphoSitePlus	COSMIC	39.062	Up-regulation
Other_Aur_AURKA_ST	Q8TEW0	PARD3	O14965	AURKA	S962	S967G	967	Missense	distal	5	no	46.913	47.014	PhosphoSitePlus	COSMIC	39.062	Up-regulation
Other_Aur_AURKA_ST	Q8TEW0	PARD3	O14965	AURKA	S962	S962F	962	Missense	central	0	yes	46.913	0.000	PhosphoSitePlus	COSMIC	39.062	Loss
Other_Aur_AURKA_ST	Q8TEW0	PARD3	O14965	AURKA	S962	S956F	956	Missense	distal	-6	no	46.913	41.255	PhosphoSitePlus	COSMIC	39.062	Down-regulation
Other_Aur_AURKA_ST	Q8TEW0	PARD3	O14965	AURKA	S962	E961K	961	Missense	proximal	-1	no	46.913	47.333	PhosphoSitePlus	COSMIC	39.062	Up-regulation
Other_Aur_AURKA_ST	Q8TEW0	PARD3	O14965	AURKA	S964	G959D	959	Missense	distal	-5	no	41.899	41.932	EPSD	COSMIC	39.062	Up-regulation
Other_Aur_AURKA_ST	Q8TEW0	PARD3	O14965	AURKA	S964	S964G	964	Missense	central	0	yes	41.899	0.000	EPSD	COSMIC	39.062	Loss
Other_Aur_AURKA_ST	Q8TEW0	PARD3	O14965	AURKA	S964	S967G	967	Missense	distal	3	no	41.899	41.493	EPSD	COSMIC	39.062	Down-regulation
Other_Aur_AURKA_ST	Q8TEW0	PARD3	O14965	AURKA	S964	S962F	962	Missense	proximal	-2	no	41.899	36.647	EPSD	COSMIC	39.062	Loss
Other_Aur_AURKA_ST	Q8TEW0	PARD3	O14965	AURKA	S964	E961K	961	Missense	distal	-3	no	41.899	43.438	EPSD	COSMIC	39.062	Up-regulation
Other_Aur_AURKA_ST	Q8TEW0	PARD3	O14965	AURKA	S973	M978T	978	Missense	distal	5	no	38.590	40.749	EPSD	COSMIC	39.062	Gain
Other_Aur_AURKA_ST	Q8TEW0	PARD3	O14965	AURKA	S1046	E1045K	1045	Missense	proximal	-1	no	42.732	43.152	EPSD	COSMIC	39.062	Up-regulation
Other_Aur_AURKA_ST	Q8TEW0	PARD3	O14965	AURKA	S1046	G1039W	1039	Missense	distal	-7	no	42.732	41.319	EPSD	COSMIC	39.062	Down-regulation
Other_Aur_AURKA_ST	Q8TEW0	PARD3	O14965	AURKA	S1046	E1051K	1051	Missense	distal	5	no	42.732	43.259	EPSD	COSMIC	39.062	Up-regulation
Other_Aur_AURKA_ST	Q8TEW0	PARD3	O14965	AURKA	S1102	S1103F	1103	Missense	proximal	1	no	34.363	40.843	EPSD	COSMIC	39.062	Gain
Other_Aur_AURKA_ST	Q8TEW0	PARD3	O14965	AURKA	S1102	G1100R	1100	Missense	proximal	-2	no	34.363	44.507	EPSD	COSMIC	39.062	Gain
Other_Aur_AURKA_ST	Q8TEW0	PARD3	O14965	AURKA	S1103	G1100R	1100	Missense	distal	-3	no	35.100	40.294	EPSD	COSMIC	39.062	Gain
Other_Aur_AURKA_ST	Q8TEW0	PARD3	O14965	AURKA	S1136	S1136F	1136	Missense	central	0	yes	48.417	0.000	EPSD	COSMIC	39.062	Loss
Other_Aur_AURKA_ST	Q8TEW0	PARD3	O14965	AURKA	S1136	P1133L	1133	Missense	distal	-3	no	48.417	49.560	EPSD	COSMIC	39.062	Up-regulation
Other_Aur_AURKA_ST	Q8TEW0	PARD3	O14965	AURKA	S1136	V1141I	1141	Missense	distal	5	no	48.417	50.174	EPSD	COSMIC	39.062	Up-regulation
Other_Aur_AURKA_ST	Q8TEW0	PARD3	O14965	AURKA	S1139	S1146F	1146	Missense	distal	7	no	43.696	43.718	EPSD	COSMIC	39.062	Up-regulation
Other_Aur_AURKA_ST	Q8TEW0	PARD3	O14965	AURKA	S1139	S1136F	1136	Missense	distal	-3	no	43.696	38.080	EPSD	COSMIC	39.062	Loss
Other_Aur_AURKA_ST	Q8TEW0	PARD3	O14965	AURKA	S1139	P1133L	1133	Missense	distal	-6	no	43.696	42.716	EPSD	COSMIC	39.062	Down-regulation
Other_Aur_AURKA_ST	Q8TEW0	PARD3	O14965	AURKA	S1139	V1141I	1141	Missense	proximal	2	no	43.696	43.362	EPSD	COSMIC	39.062	Down-regulation
Other_Aur_AURKA_ST	Q8TEW0	PARD3	O14965	AURKA	T1147	R1153H	1153	Missense	distal	6	no	45.841	45.844	EPSD	COSMIC	39.062	Up-regulation
Other_Aur_AURKA_ST	Q8TEW0	PARD3	O14965	AURKA	T1147	S1149Y	1149	Missense	proximal	2	no	45.841	47.082	EPSD	COSMIC	39.062	Up-regulation
Other_Aur_AURKA_ST	Q8TEW0	PARD3	O14965	AURKA	T1147	S1149F	1149	Missense	proximal	2	no	45.841	45.145	EPSD	COSMIC	39.062	Down-regulation
Other_Aur_AURKA_ST	Q8TEW0	PARD3	O14965	AURKA	T1147	S1146F	1146	Missense	proximal	-1	no	45.841	46.914	EPSD	COSMIC	39.062	Up-regulation
Other_Aur_AURKA_ST	Q8TEW0	PARD3	O14965	AURKA	T1147	S1149G	1149	Missense	proximal	2	no	45.841	46.006	EPSD	COSMIC	39.062	Up-regulation
Other_Aur_AURKA_ST	Q8TEW0	PARD3	O14965	AURKA	T1147	P1148T	1148	Missense	proximal	1	no	45.841	48.089	EPSD	COSMIC	39.062	Up-regulation
Other_Aur_AURKA_ST	Q8TEW0	PARD3	O14965	AURKA	T1147	V1141I	1141	Missense	distal	-6	no	45.841	39.059	EPSD	COSMIC	39.062	Loss
Other_Aur_AURKA_ST	Q8TEW0	PARD3	O14965	AURKA	T1147	H1151N	1151	Missense	distal	4	no	45.841	44.828	EPSD	COSMIC	39.062	Down-regulation
Other_Aur_AURKA_ST	Q8TEW0	PARD3	O14965	AURKA	T1176	R1174C	1174	Missense	proximal	-2	no	47.137	31.840	EPSD	COSMIC	39.062	Loss
Other_Aur_AURKA_ST	Q8TEW0	PARD3	O14965	AURKA	T1176	R1173H	1173	Missense	distal	-3	no	47.137	41.364	EPSD	COSMIC	39.062	Down-regulation
Other_Aur_AURKA_ST	Q8TEW0	PARD3	O14965	AURKA	T1176	R1175Q	1175	Missense	proximal	-1	no	47.137	46.797	EPSD	COSMIC	39.062	Down-regulation
Other_Aur_AURKA_ST	Q8TEW0	PARD3	O14965	AURKA	T1176	R1174Q	1174	Missense	proximal	-2	no	47.137	36.498	EPSD	COSMIC	39.062	Loss
Other_Aur_AURKA_ST	Q8TEW0	PARD3	O14965	AURKA	T1176	S1178I	1178	Missense	proximal	2	no	47.137	46.350	EPSD	COSMIC;GDSC;CCLE	39.062	Down-regulation
Other_Aur_AURKA_ST	Q8TEW0	PARD3	O14965	AURKA	T1176	E1180G	1180	Missense	distal	4	no	47.137	46.955	EPSD	COSMIC	39.062	Down-regulation
Other_Aur_AURKA_ST	Q8TEW0	PARD3	O14965	AURKA	S1196	S1192G	1192	Missense	distal	-4	no	52.969	51.849	EPSD	COSMIC	39.062	Down-regulation
Other_Aur_AURKA_ST	Q8TEW0	PARD3	O14965	AURKA	S1196	Q1202H	1202	Missense	distal	6	no	52.969	53.016	EPSD	COSMIC	39.062	Up-regulation
Other_Aur_AURKA_ST	Q8TEW0	PARD3	O14965	AURKA	S1196	T1190M	1190	Missense	distal	-6	no	52.969	52.497	EPSD	COSMIC;GDSC	39.062	Down-regulation
Other_Aur_AURKA_ST	Q8TEW0	PARD3	O14965	AURKA	S1222	A1217T	1217	Missense	distal	-5	no	42.703	42.742	EPSD	COSMIC	39.062	Up-regulation
Other_Aur_AURKA_ST	Q8TEW0	PARD3	O14965	AURKA	S1222	Q1227H	1227	Missense	distal	5	no	42.703	40.832	EPSD	COSMIC	39.062	Down-regulation
Other_Aur_AURKA_ST	Q8TEW0	PARD3	O14965	AURKA	S1222	S1222L	1222	Missense	central	0	yes	42.703	0.000	EPSD	COSMIC	39.062	Loss
Other_Aur_AURKA_ST	Q8TEW0	PARD3	O14965	AURKA	S1222	S1223Y	1223	Missense	proximal	1	no	42.703	46.780	EPSD	COSMIC	39.062	Up-regulation
Other_Aur_AURKA_ST	Q8TEW0	PARD3	O14965	AURKA	S1222	S1223F	1223	Missense	proximal	1	no	42.703	49.183	EPSD	COSMIC	39.062	Up-regulation
Other_Aur_AURKA_ST	Q8TEW0	PARD3	O14965	AURKA	S1222	Y1221H	1221	Missense	proximal	-1	no	42.703	43.227	EPSD	COSMIC	39.062	Up-regulation
Other_Aur_AURKA_ST	Q8TEW0	PARD3	O14965	AURKA	S1222	R1226Q	1226	Missense	distal	4	no	42.703	43.118	EPSD	COSMIC	39.062	Up-regulation
Other_Aur_AURKA_ST	Q8TEW0	PARD3	O14965	AURKA	S1222	R1226L	1226	Missense	distal	4	no	42.703	43.328	EPSD	COSMIC	39.062	Up-regulation
Other_Aur_AURKA_ST	Q8TEW0	PARD3	O14965	AURKA	S1222	R1229S	1229	Missense	distal	7	no	42.703	42.722	EPSD	COSMIC	39.062	Up-regulation
Other_Aur_AURKA_ST	Q8TEW0	PARD3	O14965	AURKA	S1222	P1225T	1225	Missense	distal	3	no	42.703	40.769	EPSD	COSMIC	39.062	Down-regulation
Other_Aur_AURKA_ST	Q8TEW0	PARD3	O14965	AURKA	S1222	P1225S	1225	Missense	distal	3	no	42.703	43.355	EPSD	COSMIC	39.062	Up-regulation
Other_Aur_AURKA_ST	Q8TEW0	PARD3	O14965	AURKA	S1236	Q1237E	1237	Missense	proximal	1	no	41.394	39.144	EPSD	COSMIC	39.062	Down-regulation
Other_Aur_AURKA_ST	Q8TEW0	PARD3	O14965	AURKA	S1236	A1232T	1232	Missense	distal	-4	no	41.394	46.352	EPSD	COSMIC	39.062	Up-regulation
Other_Aur_AURKA_ST	Q8TEW0	PARD3	O14965	AURKA	S1236	S1236G	1236	Missense	central	0	yes	41.394	0.000	EPSD	COSMIC	39.062	Loss
Other_Aur_AURKA_ST	Q8TEW0	PARD3	O14965	AURKA	S1236	R1229S	1229	Missense	distal	-7	no	41.394	40.820	EPSD	COSMIC	39.062	Down-regulation
Other_Aur_AURKA_ST	Q8TEW0	PARD3	O14965	AURKA	S1236	S1234L	1234	Missense	proximal	-2	no	41.394	44.831	EPSD	COSMIC	39.062	Up-regulation
Other_Aur_AURKA_ST	Q8TEW0	PARD3	O14965	AURKA	S1236	W1240S	1240	Missense	distal	4	no	41.394	40.973	EPSD	COSMIC	39.062	Down-regulation
Other_Aur_AURKA_ST	Q8TEW0	PARD3	O14965	AURKA	S1236	S1239F	1239	Missense	distal	3	no	41.394	41.448	EPSD	COSMIC	39.062	Up-regulation
Other_Aur_AURKA_ST	Q8TEW0	PARD3	O14965	AURKA	S1236	E1241K	1241	Missense	distal	5	no	41.394	41.921	EPSD	COSMIC	39.062	Up-regulation
Other_Aur_AURKA_ST	Q8TEW0	PARD3	O14965	AURKA	S1320	Q1317H	1317	Missense	distal	-3	no	36.682	40.573	EPSD	COSMIC	39.062	Gain
Other_Aur_AURKA_ST	Q8NHV4	NEDD1	O14965	AURKA	S89	V83A	83	Missense	distal	-6	no	40.660	41.496	EPSD	COSMIC	39.062	Up-regulation
Other_Aur_AURKA_ST	Q8NHV4	NEDD1	O14965	AURKA	S89	G95R	95	Missense	distal	6	no	40.660	40.643	EPSD	COSMIC	39.062	Down-regulation
Other_Aur_AURKA_ST	Q8NHV4	NEDD1	O14965	AURKA	S89	L92F	92	Missense	distal	3	no	40.660	41.829	EPSD	COSMIC	39.062	Up-regulation
Other_Aur_AURKA_ST	Q8NHV4	NEDD1	O14965	AURKA	S89	V83D	83	Missense	distal	-6	no	40.660	38.465	EPSD	COSMIC	39.062	Loss
Other_Aur_AURKA_ST	Q8NHV4	NEDD1	O14965	AURKA	S89	M90L	90	Missense	proximal	1	no	40.660	41.570	EPSD	COSMIC	39.062	Up-regulation
Other_Aur_AURKA_ST	Q8NHV4	NEDD1	O14965	AURKA	S171	H167Y	167	Missense	distal	-4	no	34.492	39.781	EPSD	COSMIC	39.062	Gain
Other_Aur_AURKA_ST	Q8NHV4	NEDD1	O14965	AURKA	S215	N218D	218	Missense	distal	3	no	39.454	43.940	EPSD	COSMIC	39.062	Up-regulation
Other_Aur_AURKA_ST	Q8NHV4	NEDD1	O14965	AURKA	S405	P412L	412	Missense	distal	7	no	46.873	46.956	PhosphoSitePlus	COSMIC	39.062	Up-regulation
Other_Aur_AURKA_ST	Q8NHV4	NEDD1	O14965	AURKA	S455	S455L	455	Missense	central	0	yes	41.402	0.000	EPSD	COSMIC;CCLE	39.062	Loss
Other_Aur_AURKA_ST	Q8NHV4	NEDD1	O14965	AURKA	T480	I486M	486	Missense	distal	6	no	41.078	41.075	EPSD	COSMIC	39.062	Down-regulation
Other_Aur_AURKA_ST	Q8NHV4	NEDD1	O14965	AURKA	T522	N524I	524	Missense	proximal	2	no	47.600	47.379	EPSD	COSMIC	39.062	Down-regulation
Other_Aur_AURKA_ST	Q8NHV4	NEDD1	O14965	AURKA	T522	T522A	522	Missense	central	0	yes	47.600	0.000	EPSD	COSMIC	39.062	Loss
Other_Aur_AURKA_ST	Q8NHV4	NEDD1	O14965	AURKA	T522	N520K	520	Missense	proximal	-2	no	47.600	51.579	EPSD	COSMIC	39.062	Up-regulation
Other_Aur_AURKA_ST	Q8NHV4	NEDD1	O14965	AURKA	T522	S518L	518	Missense	distal	-4	no	47.600	46.834	EPSD	COSMIC	39.062	Down-regulation
Other_Aur_AURKA_ST	Q8NHV4	NEDD1	O14965	AURKA	T522	S525L	525	Missense	distal	3	no	47.600	46.485	EPSD	COSMIC	39.062	Down-regulation
Other_Aur_AURKA_ST	Q8NHV4	NEDD1	O14965	AURKA	S574	R579Q	579	Missense	distal	5	no	39.818	42.198	EPSD	COSMIC	39.062	Up-regulation
Other_Aur_AURKA_ST	Q8NHV4	NEDD1	O14965	AURKA	S574	A572V	572	Missense	proximal	-2	no	39.818	40.416	EPSD	COSMIC;CCLE	39.062	Up-regulation
Other_Aur_AURKA_ST	Q8NHV4	NEDD1	O14965	AURKA	S586	R579Q	579	Missense	distal	-7	no	41.236	40.714	EPSD	COSMIC	39.062	Down-regulation
Other_Aur_AURKA_ST	P53350	PLK1	O14965	AURKA	T210	G205V	205	Missense	distal	-5	no	45.299	45.310	PhosphoSitePlus	COSMIC	39.062	Up-regulation
Other_Aur_AURKA_ST	P53350	PLK1	O14965	AURKA	S326	A328T	328	Missense	proximal	2	no	44.780	43.520	EPSD	COSMIC	39.062	Down-regulation
Other_Aur_AURKA_ST	P53350	PLK1	O14965	AURKA	T366	G367V	367	Missense	proximal	1	no	37.157	39.497	EPSD	COSMIC	39.062	Gain
Other_Aur_AURKA_ST	P53350	PLK1	O14965	AURKA	S375	S375G	375	Missense	central	0	yes	39.292	0.000	EPSD	COSMIC;GDSC;CCLE	39.062	Loss
Other_Aur_AURKA_ST	P53350	PLK1	O14965	AURKA	S387	R392H	392	Missense	distal	5	no	38.699	39.208	EPSD	COSMIC	39.062	Gain
Other_Aur_AURKA_ST	P53350	PLK1	O14965	AURKA	S387	R392C	392	Missense	distal	5	no	38.699	40.849	EPSD	COSMIC	39.062	Gain
Other_Aur_AURKA_ST	P03372	ESR1	O14965	AURKA	S46	S47T	47	Missense	proximal	1	no	39.630	42.878	EPSD	COSMIC	39.062	Up-regulation
Other_Aur_AURKA_ST	P03372	ESR1	O14965	AURKA	S46	A50T	50	Missense	distal	4	no	39.630	38.582	EPSD	COSMIC	39.062	Loss
Other_Aur_AURKA_ST	P03372	ESR1	O14965	AURKA	S46	K48N	48	Missense	proximal	2	no	39.630	41.674	EPSD	COSMIC	39.062	Up-regulation
Other_Aur_AURKA_ST	P03372	ESR1	O14965	AURKA	S46	D45N	45	Missense	proximal	-1	no	39.630	36.469	EPSD	COSMIC	39.062	Loss
Other_Aur_AURKA_ST	P03372	ESR1	O14965	AURKA	S46	P49S	49	Missense	distal	3	no	39.630	40.282	EPSD	COSMIC	39.062	Up-regulation
Other_Aur_AURKA_ST	P03372	ESR1	O14965	AURKA	S154	A148E	148	Missense	distal	-6	no	44.115	40.762	EPSD	COSMIC	39.062	Down-regulation
Other_Aur_AURKA_ST	P03372	ESR1	O14965	AURKA	S154	R151K	151	Missense	distal	-3	no	44.115	36.289	EPSD	COSMIC	39.062	Loss
Other_Aur_AURKA_ST	P03372	ESR1	O14965	AURKA	S154	P147Q	147	Missense	distal	-7	no	44.115	42.306	EPSD	COSMIC	39.062	Down-regulation
Other_Aur_AURKA_ST	P03372	ESR1	O14965	AURKA	S154	R158C	158	Missense	distal	4	no	44.115	44.089	EPSD	COSMIC	39.062	Down-regulation
Other_Aur_AURKA_ST	P03372	ESR1	O14965	AURKA	S154	Q159L	159	Missense	distal	5	no	44.115	41.642	EPSD	COSMIC	39.062	Down-regulation
Other_Aur_AURKA_ST	P03372	ESR1	O14965	AURKA	S154	R157Q	157	Missense	distal	3	no	44.115	44.504	EPSD	COSMIC	39.062	Up-regulation
Other_Aur_AURKA_ST	P03372	ESR1	O14965	AURKA	S154	N156T	156	Missense	proximal	2	no	44.115	41.537	EPSD	COSMIC	39.062	Down-regulation
Other_Aur_AURKA_ST	P03372	ESR1	O14965	AURKA	S154	G160D	160	Missense	distal	6	no	44.115	44.266	EPSD	COSMIC	39.062	Up-regulation
Other_Aur_AURKA_ST	P03372	ESR1	O14965	AURKA	S154	P152S	152	Missense	proximal	-2	no	44.115	46.016	EPSD	COSMIC	39.062	Up-regulation
Other_Aur_AURKA_ST	P03372	ESR1	O14965	AURKA	S154	P152L	152	Missense	proximal	-2	no	44.115	49.453	EPSD	COSMIC	39.062	Up-regulation
Other_Aur_AURKA_ST	P03372	ESR1	O14965	AURKA	S167	G172R	172	Missense	distal	5	no	51.493	50.240	PhosphoSitePlus;EPSD	COSMIC	39.062	Down-regulation
Other_Aur_AURKA_ST	P03372	ESR1	O14965	AURKA	S167	M174I	174	Missense	distal	7	no	51.493	51.646	PhosphoSitePlus;EPSD	COSMIC	39.062	Up-regulation
Other_Aur_AURKA_ST	P03372	ESR1	O14965	AURKA	S167	D170Y	170	Missense	distal	3	no	51.493	50.726	PhosphoSitePlus;EPSD	COSMIC	39.062	Down-regulation
Other_Aur_AURKA_ST	P03372	ESR1	O14965	AURKA	S167	G160D	160	Missense	distal	-7	no	51.493	52.534	PhosphoSitePlus;EPSD	COSMIC	39.062	Up-regulation
Other_Aur_AURKA_ST	P03372	ESR1	O14965	AURKA	S236	R241G	241	Missense	distal	5	no	39.350	40.604	EPSD	COSMIC	39.062	Up-regulation
Other_Aur_AURKA_ST	P03372	ESR1	O14965	AURKA	S236	R241W	241	Missense	distal	5	no	39.350	40.349	EPSD	COSMIC	39.062	Up-regulation
Other_Aur_AURKA_ST	P03372	ESR1	O14965	AURKA	S236	R233G	233	Missense	distal	-3	no	39.350	34.157	EPSD	COSMIC	39.062	Loss
Other_Aur_AURKA_ST	P03372	ESR1	O14965	AURKA	S236	C237Y	237	Missense	proximal	1	no	39.350	45.341	EPSD	COSMIC	39.062	Up-regulation
Other_Aur_AURKA_ST	P03372	ESR1	O14965	AURKA	S236	Q238H	238	Missense	proximal	2	no	39.350	36.245	EPSD	COSMIC;CCLE	39.062	Loss
Other_Aur_AURKA_ST	P03372	ESR1	O14965	AURKA	S236	R243L	243	Missense	distal	7	no	39.350	39.342	EPSD	COSMIC	39.062	Down-regulation
Other_Aur_AURKA_ST	P03372	ESR1	O14965	AURKA	S305	K303R	303	Missense	proximal	-2	no	43.639	50.143	EPSD;PhosphoSitePlus	COSMIC	39.062	Up-regulation
Other_Aur_AURKA_ST	P03372	ESR1	O14965	AURKA	S305	K299R	299	Missense	distal	-6	no	43.639	46.624	EPSD;PhosphoSitePlus	COSMIC	39.062	Up-regulation
Other_Aur_AURKA_ST	P03372	ESR1	O14965	AURKA	S305	N304S	304	Missense	proximal	-1	no	43.639	45.479	EPSD;PhosphoSitePlus	COSMIC	39.062	Up-regulation
Other_Aur_AURKA_ST	P03372	ESR1	O14965	AURKA	S305	R300C	300	Missense	distal	-5	no	43.639	43.762	EPSD;PhosphoSitePlus	COSMIC;CCLE	39.062	Up-regulation
Other_Aur_AURKA_ST	P03372	ESR1	O14965	AURKA	S305	A307P	307	Missense	proximal	2	no	43.639	44.275	EPSD;PhosphoSitePlus	COSMIC	39.062	Up-regulation
Other_Aur_AURKA_ST	P03372	ESR1	O14965	AURKA	S305	N304H	304	Missense	proximal	-1	no	43.639	45.058	EPSD;PhosphoSitePlus	COSMIC	39.062	Up-regulation
Other_Aur_AURKA_ST	P03372	ESR1	O14965	AURKA	S559	G557R	557	Missense	proximal	-2	no	46.323	56.467	EPSD	COSMIC	39.062	Up-regulation
Other_Aur_AURKA_ST	P03372	ESR1	O14965	AURKA	S559	D564Y	564	Missense	distal	5	no	46.323	45.442	EPSD	COSMIC	39.062	Down-regulation
Other_Aur_AURKA_ST	P03372	ESR1	O14965	AURKA	S559	V560M	560	Missense	proximal	1	no	46.323	46.322	EPSD	COSMIC	39.062	Down-regulation
Other_Aur_AURKA_ST	P03372	ESR1	O14965	AURKA	S559	D564N	564	Missense	distal	5	no	46.323	45.000	EPSD	COSMIC	39.062	Down-regulation
Other_Aur_AURKA_ST	P06748	NPM1	O14965	AURKA	S227	G224R	224	Missense	distal	-3	no	34.455	39.649	EPSD	COSMIC	39.062	Gain
Other_Aur_AURKA_ST	P06748	NPM1	O14965	AURKA	S243	D246N	246	Missense	distal	3	no	45.603	41.117	EPSD	COSMIC	39.062	Down-regulation
Other_Aur_AURKA_ST	P06748	NPM1	O14965	AURKA	S243	A249G	249	Missense	distal	6	no	45.603	45.593	EPSD	COSMIC	39.062	Down-regulation
Other_Aur_AURKA_ST	P06748	NPM1	O14965	AURKA	S260	I255V	255	Missense	distal	-5	no	43.470	43.467	EPSD	COSMIC	39.062	Down-regulation
Other_Aur_AURKA_ST	P06748	NPM1	O14965	AURKA	S260	K263E	263	Missense	distal	3	no	43.470	44.866	EPSD	COSMIC	39.062	Up-regulation
Other_Aur_AURKA_ST	P06748	NPM1	O14965	AURKA	S260	L261F	261	Missense	proximal	1	no	43.470	44.300	EPSD	COSMIC	39.062	Up-regulation
Other_Aur_AURKA_ST	P06748	NPM1	O14965	AURKA	S260	S260C	260	Missense	central	0	yes	43.470	0.000	EPSD	COSMIC	39.062	Loss
Other_Aur_AURKA_ST	Q15398	DLGAP5	O14965	AURKA	S188	K192E	192	Missense	distal	4	no	40.319	40.335	EPSD	COSMIC	39.062	Up-regulation
Other_Aur_AURKA_ST	Q15398	DLGAP5	O14965	AURKA	S188	V194A	194	Missense	distal	6	no	40.319	40.416	EPSD	COSMIC	39.062	Up-regulation
Other_Aur_AURKA_ST	Q15398	DLGAP5	O14965	AURKA	T210	A209S	209	Missense	proximal	-1	no	43.258	43.146	EPSD	COSMIC;GDSC;CCLE	39.062	Down-regulation
Other_Aur_AURKA_ST	Q15398	DLGAP5	O14965	AURKA	T210	L203F	203	Missense	distal	-7	no	43.258	42.902	EPSD	COSMIC	39.062	Down-regulation
Other_Aur_AURKA_ST	Q15398	DLGAP5	O14965	AURKA	S624	P619R	619	Missense	distal	-5	no	42.673	42.698	EPSD	COSMIC	39.062	Up-regulation
Other_Aur_AURKA_ST	Q15398	DLGAP5	O14965	AURKA	S630	Q635E	635	Missense	distal	5	no	45.450	44.229	EPSD	COSMIC	39.062	Down-regulation
Other_Aur_AURKA_ST	Q15398	DLGAP5	O14965	AURKA	S634	G638E	638	Missense	distal	4	no	40.250	40.432	EPSD	COSMIC	39.062	Up-regulation
Other_Aur_AURKA_ST	Q15398	DLGAP5	O14965	AURKA	S634	P640H	640	Missense	distal	6	no	40.250	40.292	EPSD	COSMIC	39.062	Up-regulation
Other_Aur_AURKA_ST	Q15398	DLGAP5	O14965	AURKA	S634	Q635E	635	Missense	proximal	1	no	40.250	38.000	EPSD	COSMIC	39.062	Loss
Other_Aur_AURKA_ST	Q15398	DLGAP5	O14965	AURKA	S690	I684V	684	Missense	distal	-6	no	42.807	49.588	EPSD	COSMIC	39.062	Up-regulation
Other_Aur_AURKA_ST	Q15398	DLGAP5	O14965	AURKA	S757	T759I	759	Missense	proximal	2	no	43.830	46.187	EPSD;PhosphoSitePlus	COSMIC	39.062	Up-regulation
Other_Aur_AURKA_ST	Q13158	FADD	O14965	AURKA	S41	R34H	34	Missense	distal	-7	no	42.277	40.801	EPSD	COSMIC	39.062	Down-regulation
Other_Aur_AURKA_ST	Q13158	FADD	O14965	AURKA	S69	R71W	71	Missense	proximal	2	no	42.411	42.201	EPSD	COSMIC	39.062	Down-regulation
Other_Aur_AURKA_ST	Q9NRM7	LATS2	O14965	AURKA	S172	T165A	165	Missense	distal	-7	no	62.398	62.856	EPSD	COSMIC	39.062	Up-regulation
Other_Aur_AURKA_ST	Q9NRM7	LATS2	O14965	AURKA	S172	R169Q	169	Missense	distal	-3	no	62.398	52.734	EPSD	COSMIC;GDSC	39.062	Down-regulation
Other_Aur_AURKA_ST	Q9NRM7	LATS2	O14965	AURKA	S172	D178N	178	Missense	distal	6	no	62.398	61.991	EPSD	COSMIC	39.062	Down-regulation
Other_Aur_AURKA_ST	Q9NRM7	LATS2	O14965	AURKA	S272	R271H	271	Missense	proximal	-1	no	40.852	40.443	EPSD	COSMIC;CCLE	39.062	Down-regulation
Other_Aur_AURKA_ST	Q9NRM7	LATS2	O14965	AURKA	S272	S274F	274	Missense	proximal	2	no	40.852	40.156	EPSD	COSMIC	39.062	Down-regulation
Other_Aur_AURKA_ST	Q9NRM7	LATS2	O14965	AURKA	S274	R271H	271	Missense	distal	-3	no	51.716	45.943	EPSD	COSMIC;CCLE	39.062	Down-regulation
Other_Aur_AURKA_ST	Q9NRM7	LATS2	O14965	AURKA	S274	S274F	274	Missense	central	0	yes	51.716	0.000	EPSD	COSMIC	39.062	Loss
Other_Aur_AURKA_ST	Q9NRM7	LATS2	O14965	AURKA	S288	A287D	287	Missense	proximal	-1	no	38.898	40.108	EPSD	COSMIC	39.062	Gain
Other_Aur_AURKA_ST	Q9NRM7	LATS2	O14965	AURKA	S380	S380F	380	Missense	central	0	yes	70.275	0.000	EPSD;PhosphoSitePlus	COSMIC	39.062	Loss
Other_Aur_AURKA_ST	Q9NRM7	LATS2	O14965	AURKA	S380	R378W	378	Missense	proximal	-2	no	70.275	-116.433	EPSD;PhosphoSitePlus	COSMIC	39.062	Loss
Other_Aur_AURKA_ST	Q9NRM7	LATS2	O14965	AURKA	S380	D379G	379	Missense	proximal	-1	no	70.275	69.012	EPSD;PhosphoSitePlus	COSMIC	39.062	Down-regulation
Other_Aur_AURKA_ST	Q9NRM7	LATS2	O14965	AURKA	S411	S408C	408	Missense	distal	-3	no	37.293	39.236	EPSD	COSMIC	39.062	Gain
Other_Aur_AURKA_ST	Q9NRM7	LATS2	O14965	AURKA	S576	Q574R	574	Missense	proximal	-2	no	45.265	55.904	EPSD	COSMIC	39.062	Up-regulation
Other_Aur_AURKA_ST	Q9NRM7	LATS2	O14965	AURKA	S576	P579L	579	Missense	distal	3	no	45.265	44.801	EPSD	COSMIC	39.062	Down-regulation
Other_Aur_AURKA_ST	Q9NRM7	LATS2	O14965	AURKA	S576	D569G	569	Missense	distal	-7	no	45.265	44.224	EPSD	COSMIC;GDSC;CCLE	39.062	Down-regulation
Other_Aur_AURKA_ST	Q9NRM7	LATS2	O14965	AURKA	S598	S596R	596	Missense	proximal	-2	no	35.647	48.805	EPSD	COSMIC	39.062	Gain
Other_Aur_AURKA_ST	Q9NRM7	LATS2	O14965	AURKA	S598	P599L	599	Missense	proximal	1	no	35.647	40.297	EPSD	COSMIC	39.062	Gain
Other_Aur_AURKA_ST	Q9NRM7	LATS2	O14965	AURKA	S598	K595R	595	Missense	distal	-3	no	35.647	43.473	EPSD	COSMIC	39.062	Gain
Other_Aur_AURKA_ST	Q9NRM7	LATS2	O14965	AURKA	S829	Q826H	826	Missense	distal	-3	no	36.146	40.037	EPSD	COSMIC	39.062	Gain
Other_Aur_AURKA_ST	Q9NRM7	LATS2	O14965	AURKA	S835	P838S	838	Missense	distal	3	no	49.319	49.970	EPSD	COSMIC	39.062	Up-regulation
Other_Aur_AURKA_ST	O15350	TP73	O14965	AURKA	S223	D227G	227	Missense	distal	4	no	40.317	40.388	EPSD	COSMIC	39.062	Up-regulation
Other_Aur_AURKA_ST	O15350	TP73	O14965	AURKA	S223	R216L	216	Missense	distal	-7	no	40.317	39.931	EPSD	COSMIC	39.062	Down-regulation
Other_Aur_AURKA_ST	O15350	TP73	O14965	AURKA	S223	G219D	219	Missense	distal	-4	no	40.317	37.931	EPSD	COSMIC	39.062	Loss
Other_Aur_AURKA_ST	O15350	TP73	O14965	AURKA	S289	G292C	292	Missense	distal	3	no	54.533	52.602	EPSD	COSMIC	39.062	Down-regulation
Other_Aur_AURKA_ST	O15350	TP73	O14965	AURKA	S471	S468N	468	Missense	distal	-3	no	40.632	41.276	EPSD	COSMIC	39.062	Up-regulation
Other_Aur_AURKA_ST	O15350	TP73	O14965	AURKA	S471	S474P	474	Missense	distal	3	no	40.632	39.980	EPSD	COSMIC	39.062	Down-regulation
Other_Aur_AURKA_ST	O15350	TP73	O14965	AURKA	S471	G478R	478	Missense	distal	7	no	40.632	40.494	EPSD	COSMIC;CCLE	39.062	Down-regulation
Other_Aur_AURKA_ST	O15350	TP73	O14965	AURKA	S471	G464S	464	Missense	distal	-7	no	40.632	41.945	EPSD	COSMIC	39.062	Up-regulation
Other_Aur_AURKA_ST	O14777	NDC80	O14965	AURKA	S66	I73L	73	Missense	distal	7	no	40.871	40.733	EPSD	COSMIC	39.062	Down-regulation
Other_Aur_AURKA_ST	O14777	NDC80	O14965	AURKA	S66	S69C	69	Missense	distal	3	no	40.871	38.533	EPSD	COSMIC	39.062	Loss
Other_Aur_AURKA_ST	O14777	NDC80	O14965	AURKA	S69	I73L	73	Missense	distal	4	no	48.764	48.271	EPSD;PhosphoSitePlus	COSMIC	39.062	Down-regulation
Other_Aur_AURKA_ST	O14777	NDC80	O14965	AURKA	S69	S69C	69	Missense	central	0	yes	48.764	0.000	EPSD;PhosphoSitePlus	COSMIC	39.062	Loss
Other_Aur_AURKA_ST	O14777	NDC80	O14965	AURKA	S75	I73L	73	Missense	proximal	-2	no	33.505	42.814	EPSD	COSMIC	39.062	Gain
Other_Aur_AURKA_ST	O14777	NDC80	O14965	AURKA	S499	I493M	493	Missense	distal	-6	no	32.796	39.721	EPSD	COSMIC	39.062	Gain
Other_Aur_AURKA_ST	O95983	MBD3	O14965	AURKA	S45	F43L	43	Missense	proximal	-2	no	32.989	41.678	EPSD	COSMIC	39.062	Gain
Other_Aur_AURKA_ST	O95983	MBD3	O14965	AURKA	S56	G55V	55	Missense	proximal	-1	no	48.982	47.764	EPSD	COSMIC	39.062	Down-regulation
Other_Aur_AURKA_ST	O95983	MBD3	O14965	AURKA	S56	S60G	60	Missense	distal	4	no	48.982	49.260	EPSD	COSMIC	39.062	Up-regulation
Other_Aur_AURKA_ST	O95983	MBD3	O14965	AURKA	S77	R82L	82	Missense	distal	5	no	39.538	39.445	EPSD	COSMIC;GDSC;CCLE	39.062	Down-regulation
Other_Aur_AURKA_ST	O95983	MBD3	O14965	AURKA	S85	R82L	82	Missense	distal	-3	no	47.557	40.041	PhosphoSitePlus;EPSD	COSMIC;GDSC;CCLE	39.062	Down-regulation
Other_Aur_AURKA_ST	O95983	MBD3	O14965	AURKA	S144	F149L	149	Missense	distal	5	no	41.295	39.338	EPSD	COSMIC	39.062	Down-regulation
Other_Aur_AURKA_ST	O95983	MBD3	O14965	AURKA	S144	F138L	138	Missense	distal	-6	no	41.295	45.423	EPSD	COSMIC	39.062	Up-regulation
Other_Aur_AURKA_ST	O95983	MBD3	O14965	AURKA	S144	A148T	148	Missense	distal	4	no	41.295	40.247	EPSD	COSMIC;GDSC;CCLE	39.062	Down-regulation
Other_Aur_AURKA_ST	Q99708	RBBP8	O14965	AURKA	T323	E320K	320	Missense	distal	-3	no	38.678	40.217	EPSD	COSMIC;GDSC;CCLE	39.062	Gain
Other_Aur_AURKA_ST	Q99708	RBBP8	O14965	AURKA	S327	P322H	322	Missense	distal	-5	no	46.400	46.369	EPSD;PhosphoSitePlus	COSMIC	39.062	Down-regulation
Other_Aur_AURKA_ST	Q99708	RBBP8	O14965	AURKA	S327	G331V	331	Missense	distal	4	no	46.400	45.862	EPSD;PhosphoSitePlus	COSMIC	39.062	Down-regulation
Other_Aur_AURKA_ST	Q99708	RBBP8	O14965	AURKA	S327	E320K	320	Missense	distal	-7	no	46.400	47.044	EPSD;PhosphoSitePlus	COSMIC;GDSC;CCLE	39.062	Up-regulation
Other_Aur_AURKA_ST	Q99708	RBBP8	O14965	AURKA	T361	G354V	354	Missense	distal	-7	no	39.739	41.070	EPSD	COSMIC	39.062	Up-regulation
Other_Aur_AURKA_ST	Q99708	RBBP8	O14965	AURKA	S439	P436S	436	Missense	distal	-3	no	44.122	46.302	EPSD	COSMIC;GDSC;CCLE	39.062	Up-regulation
Other_Aur_AURKA_ST	Q99708	RBBP8	O14965	AURKA	S439	G441E	441	Missense	proximal	2	no	44.122	44.413	EPSD	COSMIC;GDSC;CCLE	39.062	Up-regulation
Other_Aur_AURKA_ST	Q99708	RBBP8	O14965	AURKA	T450	E457K	457	Missense	distal	7	no	39.663	39.553	EPSD	COSMIC;GDSC;CCLE	39.062	Down-regulation
Other_Aur_AURKA_ST	Q99708	RBBP8	O14965	AURKA	T450	E453K	453	Missense	distal	3	no	39.663	38.267	EPSD	COSMIC	39.062	Loss
Other_Aur_AURKA_ST	Q99708	RBBP8	O14965	AURKA	S743	E737D	737	Missense	distal	-6	no	42.256	42.578	EPSD	COSMIC	39.062	Up-regulation
Other_Aur_AURKA_ST	Q99708	RBBP8	O14965	AURKA	S743	D742N	742	Missense	proximal	-1	no	42.256	39.095	EPSD	COSMIC	39.062	Down-regulation
Other_Aur_AURKA_ST	Q99708	RBBP8	O14965	AURKA	S743	S745C	745	Missense	proximal	2	no	42.256	44.204	EPSD	COSMIC	39.062	Up-regulation
Other_Aur_AURKA_ST	Q49MG5	MAP9	O14965	AURKA	S41	A37V	37	Missense	distal	-4	no	38.562	42.237	EPSD	COSMIC	39.062	Gain
Other_Aur_AURKA_ST	Q49MG5	MAP9	O14965	AURKA	S180	P174S	174	Missense	distal	-6	no	41.687	42.237	EPSD	COSMIC	39.062	Up-regulation
Other_Aur_AURKA_ST	Q49MG5	MAP9	O14965	AURKA	S180	K173N	173	Missense	distal	-7	no	41.687	41.389	EPSD	COSMIC	39.062	Down-regulation
Other_Aur_AURKA_ST	Q49MG5	MAP9	O14965	AURKA	S291	A298V	298	Missense	distal	7	no	42.006	42.133	EPSD	COSMIC	39.062	Up-regulation
Other_Aur_AURKA_ST	Q49MG5	MAP9	O14965	AURKA	S291	V295E	295	Missense	distal	4	no	42.006	42.726	EPSD	COSMIC	39.062	Up-regulation
Other_Aur_AURKA_ST	Q49MG5	MAP9	O14965	AURKA	S305	A298V	298	Missense	distal	-7	no	46.356	46.488	EPSD;PhosphoSitePlus	COSMIC	39.062	Up-regulation
Other_Aur_AURKA_ST	Q49MG5	MAP9	O14965	AURKA	S363	K359E	359	Missense	distal	-4	no	40.835	40.644	EPSD	COSMIC	39.062	Down-regulation
Other_Aur_AURKA_ST	Q49MG5	MAP9	O14965	AURKA	S370	M376I	376	Missense	distal	6	no	39.850	39.853	EPSD	COSMIC	39.062	Up-regulation
Other_Aur_AURKA_ST	Q49MG5	MAP9	O14965	AURKA	S370	S372F	372	Missense	proximal	2	no	39.850	39.155	EPSD	COSMIC	39.062	Down-regulation
Other_Aur_AURKA_ST	Q49MG5	MAP9	O14965	AURKA	T377	M376I	376	Missense	proximal	-1	no	39.173	40.547	EPSD	COSMIC	39.062	Up-regulation
Other_Aur_AURKA_ST	Q49MG5	MAP9	O14965	AURKA	T377	K382N	382	Missense	distal	5	no	39.173	38.249	EPSD	COSMIC;GDSC;CCLE	39.062	Loss
Other_Aur_AURKA_ST	Q49MG5	MAP9	O14965	AURKA	T377	S372F	372	Missense	distal	-5	no	39.173	39.179	EPSD	COSMIC	39.062	Up-regulation
Other_Aur_AURKA_ST	Q49MG5	MAP9	O14965	AURKA	S385	K382N	382	Missense	distal	-3	no	42.090	44.081	EPSD	COSMIC;GDSC;CCLE	39.062	Up-regulation
Other_Aur_AURKA_ST	Q49MG5	MAP9	O14965	AURKA	S385	S392L	392	Missense	distal	7	no	42.090	42.063	EPSD	COSMIC	39.062	Down-regulation
Other_Aur_AURKA_ST	Q49MG5	MAP9	O14965	AURKA	S625	S625C	625	Missense	central	0	yes	48.519	0.000	PhosphoSitePlus;EPSD	COSMIC	39.062	Loss
Other_Aur_AURKA_ST	Q49MG5	MAP9	O14965	AURKA	S625	R623H	623	Missense	proximal	-2	no	48.519	41.280	PhosphoSitePlus;EPSD	COSMIC	39.062	Down-regulation
Other_Aur_AURKA_ST	Q49MG5	MAP9	O14965	AURKA	S625	K621E	621	Missense	distal	-4	no	48.519	48.328	PhosphoSitePlus;EPSD	COSMIC	39.062	Down-regulation
Other_Aur_AURKA_ST	Q96EB6	SIRT1	O14965	AURKA	S169	E165D	165	Missense	distal	-4	no	39.321	35.098	EPSD	COSMIC	39.062	Loss
Other_Aur_AURKA_ST	Q96EB6	SIRT1	O14965	AURKA	S172	E165D	165	Missense	distal	-7	no	43.161	43.898	EPSD	COSMIC	39.062	Up-regulation
Other_Aur_AURKA_ST	Q96EB6	SIRT1	O14965	AURKA	S535	E542Q	542	Missense	distal	7	no	44.358	44.234	EPSD	COSMIC	39.062	Down-regulation
Other_Aur_AURKA_ST	Q96EB6	SIRT1	O14965	AURKA	S535	E536V	536	Missense	proximal	1	no	44.358	47.238	EPSD	COSMIC	39.062	Up-regulation
Other_Aur_AURKA_ST	Q96EB6	SIRT1	O14965	AURKA	S538	E536V	536	Missense	proximal	-2	no	29.908	39.515	EPSD	COSMIC	39.062	Gain
Other_Aur_AURKA_ST	Q96EB6	SIRT1	O14965	AURKA	S606	G608R	608	Missense	proximal	2	no	42.304	40.933	EPSD	COSMIC	39.062	Down-regulation
Other_Aur_AURKA_ST	Q96CX2	KCTD12	O14965	AURKA	S183	P186L	186	Missense	distal	3	no	42.758	42.294	EPSD	COSMIC	39.062	Down-regulation
Other_Aur_AURKA_ST	Q96CX2	KCTD12	O14965	AURKA	S185	P186L	186	Missense	proximal	1	no	36.048	40.698	EPSD	COSMIC	39.062	Gain
Other_Aur_AURKA_ST	Q96CX2	KCTD12	O14965	AURKA	S187	P186L	186	Missense	proximal	-1	no	42.744	41.389	EPSD	COSMIC	39.062	Down-regulation
Other_Aur_AURKA_ST	O43521	BCL2L11	O14965	AURKA	S87	S86T	86	Missense	proximal	-1	no	42.260	43.962	EPSD	COSMIC	39.062	Up-regulation
Other_Aur_AURKA_ST	O43521	BCL2L11	O14965	AURKA	S87	S93F	93	Missense	distal	6	no	42.260	42.406	EPSD	COSMIC	39.062	Up-regulation
Other_Aur_AURKA_ST	O43521	BCL2L11	O14965	AURKA	S87	R84K	84	Missense	distal	-3	no	42.260	34.434	EPSD	COSMIC	39.062	Loss
Other_Aur_AURKA_ST	O43521	BCL2L11	O14965	AURKA	S87	S94T	94	Missense	distal	7	no	42.260	42.196	EPSD	COSMIC	39.062	Down-regulation
Other_Aur_AURKA_ST	O43521	BCL2L11	O14965	AURKA	S90	S86T	86	Missense	distal	-4	no	41.931	43.928	EPSD	COSMIC	39.062	Up-regulation
Other_Aur_AURKA_ST	O43521	BCL2L11	O14965	AURKA	S90	F97L	97	Missense	distal	7	no	41.931	41.882	EPSD	COSMIC	39.062	Down-regulation
Other_Aur_AURKA_ST	O43521	BCL2L11	O14965	AURKA	S90	S93F	93	Missense	distal	3	no	41.931	41.986	EPSD	COSMIC	39.062	Up-regulation
Other_Aur_AURKA_ST	O43521	BCL2L11	O14965	AURKA	S90	R84K	84	Missense	distal	-6	no	41.931	38.947	EPSD	COSMIC	39.062	Loss
Other_Aur_AURKA_ST	O43521	BCL2L11	O14965	AURKA	S90	S94T	94	Missense	distal	4	no	41.931	40.916	EPSD	COSMIC	39.062	Down-regulation
Other_Aur_AURKA_ST	O43521	BCL2L11	O14965	AURKA	S92	S93F	93	Missense	proximal	1	no	35.319	41.799	EPSD	COSMIC	39.062	Gain
Other_Aur_AURKA_ST	O43521	BCL2L11	O14965	AURKA	S93	S86T	86	Missense	distal	-7	no	48.846	48.273	EPSD;PhosphoSitePlus	COSMIC	39.062	Down-regulation
Other_Aur_AURKA_ST	O43521	BCL2L11	O14965	AURKA	S93	F97L	97	Missense	distal	4	no	48.846	48.457	EPSD;PhosphoSitePlus	COSMIC	39.062	Down-regulation
Other_Aur_AURKA_ST	O43521	BCL2L11	O14965	AURKA	S93	D100G	100	Missense	distal	7	no	48.846	48.894	EPSD;PhosphoSitePlus	COSMIC	39.062	Up-regulation
Other_Aur_AURKA_ST	O43521	BCL2L11	O14965	AURKA	S93	S93F	93	Missense	central	0	yes	48.846	0.000	EPSD;PhosphoSitePlus	COSMIC	39.062	Loss
Other_Aur_AURKA_ST	O43521	BCL2L11	O14965	AURKA	S93	S94T	94	Missense	proximal	1	no	48.846	52.095	EPSD;PhosphoSitePlus	COSMIC	39.062	Up-regulation
Other_Aur_AURKA_ST	O43521	BCL2L11	O14965	AURKA	S94	F97L	97	Missense	distal	3	no	49.381	48.211	EPSD;PhosphoSitePlus	COSMIC	39.062	Down-regulation
Other_Aur_AURKA_ST	O43521	BCL2L11	O14965	AURKA	S94	D100G	100	Missense	distal	6	no	49.381	49.230	EPSD;PhosphoSitePlus	COSMIC	39.062	Down-regulation
Other_Aur_AURKA_ST	O43521	BCL2L11	O14965	AURKA	S94	S93F	93	Missense	proximal	-1	no	49.381	50.454	EPSD;PhosphoSitePlus	COSMIC	39.062	Up-regulation
Other_Aur_AURKA_ST	O43521	BCL2L11	O14965	AURKA	S98	S104R	104	Missense	distal	6	no	47.342	47.323	PhosphoSitePlus;EPSD	COSMIC	39.062	Down-regulation
Other_Aur_AURKA_ST	O43521	BCL2L11	O14965	AURKA	S98	F97L	97	Missense	proximal	-1	no	47.342	44.700	PhosphoSitePlus;EPSD	COSMIC	39.062	Down-regulation
Other_Aur_AURKA_ST	O43521	BCL2L11	O14965	AURKA	S98	D100G	100	Missense	proximal	2	no	47.342	46.281	PhosphoSitePlus;EPSD	COSMIC	39.062	Down-regulation
Other_Aur_AURKA_ST	O43521	BCL2L11	O14965	AURKA	S98	S93F	93	Missense	distal	-5	no	47.342	47.348	PhosphoSitePlus;EPSD	COSMIC	39.062	Up-regulation
Other_Aur_AURKA_ST	O43521	BCL2L11	O14965	AURKA	S98	S94T	94	Missense	distal	-4	no	47.342	49.339	PhosphoSitePlus;EPSD	COSMIC	39.062	Up-regulation
Other_Aur_AURKA_ST	O43521	BCL2L11	O14965	AURKA	S104	A106S	106	Missense	proximal	2	no	37.682	39.566	EPSD	COSMIC	39.062	Gain
Other_Aur_AURKA_ST	O43521	BCL2L11	O14965	AURKA	S104	D100G	100	Missense	distal	-4	no	37.682	40.068	EPSD	COSMIC	39.062	Gain
Other_Aur_AURKA_ST	O43521	BCL2L11	O14965	AURKA	S113	A106S	106	Missense	distal	-7	no	40.152	40.267	EPSD	COSMIC	39.062	Up-regulation
Other_Aur_AURKA_ST	O43521	BCL2L11	O14965	AURKA	S113	P120S	120	Missense	distal	7	no	40.152	40.262	EPSD	COSMIC	39.062	Up-regulation
Other_Aur_AURKA_ST	Q14511	NEDD9	O14965	AURKA	T104	P97S	97	Missense	distal	-7	no	46.395	44.535	EPSD	COSMIC	39.062	Down-regulation
Other_Aur_AURKA_ST	Q14511	NEDD9	O14965	AURKA	T104	P109Q	109	Missense	distal	5	no	46.395	48.284	EPSD	COSMIC	39.062	Up-regulation
Other_Aur_AURKA_ST	Q14511	NEDD9	O14965	AURKA	T104	Q98L	98	Missense	distal	-6	no	46.395	44.701	EPSD	COSMIC	39.062	Down-regulation
Other_Aur_AURKA_ST	Q14511	NEDD9	O14965	AURKA	T126	P121S	121	Missense	distal	-5	no	40.028	40.048	EPSD	COSMIC	39.062	Up-regulation
Other_Aur_AURKA_ST	Q14511	NEDD9	O14965	AURKA	S202	V205L	205	Missense	distal	3	no	42.491	42.952	EPSD	COSMIC	39.062	Up-regulation
Other_Aur_AURKA_ST	Q14511	NEDD9	O14965	AURKA	S296	R292Q	292	Missense	distal	-4	no	48.185	48.338	PhosphoSitePlus	COSMIC;CCLE	39.062	Up-regulation
Other_Aur_AURKA_ST	Q14511	NEDD9	O14965	AURKA	S375	R377L	377	Missense	proximal	2	no	42.041	42.268	EPSD	COSMIC	39.062	Up-regulation
Other_Aur_AURKA_ST	Q14511	NEDD9	O14965	AURKA	S375	T376S	376	Missense	proximal	1	no	42.041	38.792	EPSD	COSMIC	39.062	Loss
Other_Aur_AURKA_ST	Q9ULW0	TPX2	O14965	AURKA	S121	S125F	125	Missense	distal	4	no	46.346	46.829	PhosphoSitePlus;EPSD	COSMIC	39.062	Up-regulation
Other_Aur_AURKA_ST	Q9ULW0	TPX2	O14965	AURKA	S125	S125F	125	Missense	central	0	yes	55.518	0.000	EPSD;PhosphoSitePlus	COSMIC	39.062	Loss
Other_Aur_AURKA_ST	Q9ULW0	TPX2	O14965	AURKA	T195	M199I	199	Missense	distal	4	no	43.550	43.258	EPSD	COSMIC;GDSC;CCLE	39.062	Down-regulation
Other_Aur_AURKA_ST	Q9ULW0	TPX2	O14965	AURKA	S285	F283L	283	Missense	proximal	-2	no	30.618	39.307	EPSD	COSMIC	39.062	Gain
Other_Aur_AURKA_ST	Q9ULW0	TPX2	O14965	AURKA	T298	P294S	294	Missense	distal	-4	no	39.034	40.951	EPSD	COSMIC	39.062	Gain
Other_Aur_AURKA_ST	Q9ULW0	TPX2	O14965	AURKA	T298	V297A	297	Missense	proximal	-1	no	39.034	40.305	EPSD	COSMIC;GDSC;CCLE	39.062	Gain
Other_Aur_AURKA_ST	Q9ULW0	TPX2	O14965	AURKA	T298	C301Y	301	Missense	distal	3	no	39.034	41.359	EPSD	COSMIC;GDSC;CCLE	39.062	Gain
Other_Aur_AURKA_ST	Q9ULW0	TPX2	O14965	AURKA	T499	R496Q	496	Missense	distal	-3	no	40.933	31.269	EPSD	COSMIC	39.062	Loss
Other_Aur_AURKA_ST	Q9ULW0	TPX2	O14965	AURKA	T499	D506Y	506	Missense	distal	7	no	40.933	40.941	EPSD	COSMIC	39.062	Up-regulation
Other_Aur_AURKA_ST	Q9ULW0	TPX2	O14965	AURKA	T588	P592S	592	Missense	distal	4	no	45.458	45.512	EPSD	COSMIC	39.062	Up-regulation
Other_Aur_AURKA_ST	Q9UPY8	MAPRE3	O14965	AURKA	S40	Q37H	37	Missense	distal	-3	no	41.705	45.596	EPSD	COSMIC	39.062	Up-regulation
Other_Aur_AURKA_ST	Q9UPY8	MAPRE3	O14965	AURKA	S40	S40L	40	Missense	central	0	yes	41.705	0.000	EPSD	COSMIC	39.062	Loss
Other_Aur_AURKA_ST	Q9UPY8	MAPRE3	O14965	AURKA	S162	P158T	158	Missense	distal	-4	no	40.150	44.064	EPSD	COSMIC	39.062	Up-regulation
Other_Aur_AURKA_ST	Q9UPY8	MAPRE3	O14965	AURKA	S162	R160K	160	Missense	proximal	-2	no	40.150	33.646	EPSD	COSMIC	39.062	Loss
Other_Aur_AURKA_ST	Q9UPY8	MAPRE3	O14965	AURKA	S162	V157F	157	Missense	distal	-5	no	40.150	40.160	EPSD	COSMIC	39.062	Up-regulation
Other_Aur_AURKA_ST	Q9UPY8	MAPRE3	O14965	AURKA	S162	G165S	165	Missense	distal	3	no	40.150	40.556	EPSD	COSMIC	39.062	Up-regulation
Other_Aur_AURKA_ST	Q9UPY8	MAPRE3	O14965	AURKA	S176	R174Q	174	Missense	proximal	-2	no	52.054	41.415	PhosphoSitePlus	COSMIC	39.062	Down-regulation
Other_Aur_AURKA_ST	Q9UPY8	MAPRE3	O14965	AURKA	S176	S176I	176	Missense	central	0	yes	52.054	0.000	PhosphoSitePlus	COSMIC	39.062	Loss
Other_Aur_AURKA_ST	Q9UPY8	MAPRE3	O14965	AURKA	S176	A179P	179	Missense	distal	3	no	52.054	52.857	PhosphoSitePlus	COSMIC;GDSC;CCLE	39.062	Up-regulation
Other_Aur_AURKA_ST	P04637	TP53	O14965	AURKA	S37	S33T	33	Missense	distal	-4	no	38.012	40.009	EPSD	COSMIC	39.062	Gain
Other_Aur_AURKA_ST	P04637	TP53	O14965	AURKA	S37	Q38L	38	Missense	proximal	1	no	38.012	39.551	EPSD	COSMIC	39.062	Gain
Other_Aur_AURKA_ST	P04637	TP53	O14965	AURKA	S37	A39V	39	Missense	proximal	2	no	38.012	39.444	EPSD	COSMIC	39.062	Gain
Other_Aur_AURKA_ST	P04637	TP53	O14965	AURKA	S37	A39S	39	Missense	proximal	2	no	38.012	39.896	EPSD	COSMIC	39.062	Gain
Other_Aur_AURKA_ST	P04637	TP53	O14965	AURKA	S37	L35R	35	Missense	proximal	-2	no	38.012	47.733	EPSD	COSMIC	39.062	Gain
Other_Aur_AURKA_ST	P04637	TP53	O14965	AURKA	S37	L35H	35	Missense	proximal	-2	no	38.012	40.495	EPSD	COSMIC	39.062	Gain
Other_Aur_AURKA_ST	P04637	TP53	O14965	AURKA	S106	G108C	108	Missense	proximal	2	no	42.716	44.498	PhosphoSitePlus;EPSD	COSMIC	39.062	Up-regulation
Other_Aur_AURKA_ST	P04637	TP53	O14965	AURKA	S106	S99F	99	Missense	distal	-7	no	42.716	42.547	PhosphoSitePlus;EPSD	COSMIC	39.062	Down-regulation
Other_Aur_AURKA_ST	P04637	TP53	O14965	AURKA	S106	R110H	110	Missense	distal	4	no	42.716	43.385	PhosphoSitePlus;EPSD	COSMIC	39.062	Up-regulation
Other_Aur_AURKA_ST	P04637	TP53	O14965	AURKA	S106	Y107Q	107	Missense	proximal	1	no	42.716	42.749	PhosphoSitePlus;EPSD	COSMIC	39.062	Up-regulation
Other_Aur_AURKA_ST	P04637	TP53	O14965	AURKA	S106	T102I	102	Missense	distal	-4	no	42.716	35.009	PhosphoSitePlus;EPSD	COSMIC	39.062	Loss
Other_Aur_AURKA_ST	P04637	TP53	O14965	AURKA	S106	K101R	101	Missense	distal	-5	no	42.716	42.741	PhosphoSitePlus;EPSD	COSMIC	39.062	Up-regulation
Other_Aur_AURKA_ST	P04637	TP53	O14965	AURKA	S106	Y107C	107	Missense	proximal	1	no	42.716	36.724	PhosphoSitePlus;EPSD	COSMIC	39.062	Loss
Other_Aur_AURKA_ST	P04637	TP53	O14965	AURKA	S106	S106I	106	Missense	central	0	yes	42.716	0.000	PhosphoSitePlus;EPSD	COSMIC	39.062	Loss
Other_Aur_AURKA_ST	P04637	TP53	O14965	AURKA	S106	Y107H	107	Missense	proximal	1	no	42.716	39.870	PhosphoSitePlus;EPSD	COSMIC	39.062	Down-regulation
Other_Aur_AURKA_ST	P04637	TP53	O14965	AURKA	S106	T102P	102	Missense	distal	-4	no	42.716	38.801	PhosphoSitePlus;EPSD	COSMIC	39.062	Loss
Other_Aur_AURKA_ST	P04637	TP53	O14965	AURKA	S106	L111M	111	Missense	distal	5	no	42.716	42.133	PhosphoSitePlus;EPSD	COSMIC	39.062	Down-regulation
Other_Aur_AURKA_ST	P04637	TP53	O14965	AURKA	S106	F109I	109	Missense	distal	3	no	42.716	43.093	PhosphoSitePlus;EPSD	COSMIC	39.062	Up-regulation
Other_Aur_AURKA_ST	P04637	TP53	O14965	AURKA	S106	G108D	108	Missense	proximal	2	no	42.716	43.776	PhosphoSitePlus;EPSD	COSMIC	39.062	Up-regulation
Other_Aur_AURKA_ST	P04637	TP53	O14965	AURKA	S106	S99P	99	Missense	distal	-7	no	42.716	44.576	PhosphoSitePlus;EPSD	COSMIC	39.062	Up-regulation
Other_Aur_AURKA_ST	P04637	TP53	O14965	AURKA	S106	Q104H	104	Missense	proximal	-2	no	42.716	46.116	PhosphoSitePlus;EPSD	COSMIC	39.062	Up-regulation
Other_Aur_AURKA_ST	P04637	TP53	O14965	AURKA	S106	K101N	101	Missense	distal	-5	no	42.716	42.784	PhosphoSitePlus;EPSD	COSMIC	39.062	Up-regulation
Other_Aur_AURKA_ST	P04637	TP53	O14965	AURKA	S106	Q104L	104	Missense	proximal	-2	no	42.716	43.634	PhosphoSitePlus;EPSD	COSMIC	39.062	Up-regulation
Other_Aur_AURKA_ST	P04637	TP53	O14965	AURKA	S106	R110S	110	Missense	distal	4	no	42.716	43.247	PhosphoSitePlus;EPSD	COSMIC	39.062	Up-regulation
Other_Aur_AURKA_ST	P04637	TP53	O14965	AURKA	S106	G112E	112	Missense	distal	6	no	42.716	42.657	PhosphoSitePlus;EPSD	COSMIC	39.062	Down-regulation
Other_Aur_AURKA_ST	P04637	TP53	O14965	AURKA	S106	G112C	112	Missense	distal	6	no	42.716	42.528	PhosphoSitePlus;EPSD	COSMIC	39.062	Down-regulation
Other_Aur_AURKA_ST	P04637	TP53	O14965	AURKA	S106	G112S	112	Missense	distal	6	no	42.716	42.717	PhosphoSitePlus;EPSD	COSMIC	39.062	Up-regulation
Other_Aur_AURKA_ST	P04637	TP53	O14965	AURKA	S106	G112V	112	Missense	distal	6	no	42.716	42.628	PhosphoSitePlus;EPSD	COSMIC	39.062	Down-regulation
Other_Aur_AURKA_ST	P04637	TP53	O14965	AURKA	S106	G112D	112	Missense	distal	6	no	42.716	42.866	PhosphoSitePlus;EPSD	COSMIC	39.062	Up-regulation
Other_Aur_AURKA_ST	P04637	TP53	O14965	AURKA	S106	G112R	112	Missense	distal	6	no	42.716	42.699	PhosphoSitePlus;EPSD	COSMIC	39.062	Down-regulation
Other_Aur_AURKA_ST	P04637	TP53	O14965	AURKA	S106	G112A	112	Missense	distal	6	no	42.716	42.725	PhosphoSitePlus;EPSD	COSMIC	39.062	Up-regulation
Other_Aur_AURKA_ST	P04637	TP53	O14965	AURKA	S106	G112F	112	Missense	distal	6	no	42.716	42.863	PhosphoSitePlus;EPSD	COSMIC	39.062	Up-regulation
Other_Aur_AURKA_ST	P04637	TP53	O14965	AURKA	S106	F113S	113	Missense	distal	7	no	42.716	42.694	PhosphoSitePlus;EPSD	COSMIC;CCLE	39.062	Down-regulation
Other_Aur_AURKA_ST	P04637	TP53	O14965	AURKA	S106	F113P	113	Missense	distal	7	no	42.716	42.584	PhosphoSitePlus;EPSD	COSMIC	39.062	Down-regulation
Other_Aur_AURKA_ST	P04637	TP53	O14965	AURKA	S149	W146R	146	Missense	distal	-3	no	-30.341	48.831	EPSD	COSMIC	39.062	Gain
Other_Aur_AURKA_ST	P04637	TP53	O14965	AURKA	S149	W146G	146	Missense	distal	-3	no	-30.341	43.637	EPSD	COSMIC	39.062	Gain
Other_Aur_AURKA_ST	P04637	TP53	O14965	AURKA	S149	W146C	146	Missense	distal	-3	no	-30.341	44.294	EPSD	COSMIC	39.062	Gain
Other_Aur_AURKA_ST	P04637	TP53	O14965	AURKA	S183	G187V	187	Missense	distal	4	no	41.241	40.702	EPSD	COSMIC	39.062	Down-regulation
Other_Aur_AURKA_ST	P04637	TP53	O14965	AURKA	S183	G187D	187	Missense	distal	4	no	41.241	41.170	EPSD	COSMIC	39.062	Down-regulation
Other_Aur_AURKA_ST	P04637	TP53	O14965	AURKA	S183	G187A	187	Missense	distal	4	no	41.241	40.996	EPSD	COSMIC	39.062	Down-regulation
Other_Aur_AURKA_ST	P04637	TP53	O14965	AURKA	S183	S183C	183	Missense	central	0	yes	41.241	0.000	EPSD	COSMIC	39.062	Loss
Other_Aur_AURKA_ST	P04637	TP53	O14965	AURKA	S183	S183P	183	Missense	central	0	yes	41.241	0.000	EPSD	COSMIC	39.062	Loss
Other_Aur_AURKA_ST	P04637	TP53	O14965	AURKA	S183	S185G	185	Missense	proximal	2	no	41.241	41.406	EPSD	COSMIC	39.062	Up-regulation
Other_Aur_AURKA_ST	P04637	TP53	O14965	AURKA	S183	P190N	190	Missense	distal	7	no	41.241	41.272	EPSD	COSMIC	39.062	Up-regulation
Other_Aur_AURKA_ST	P04637	TP53	O14965	AURKA	S183	D184N	184	Missense	proximal	1	no	41.241	35.666	EPSD	COSMIC	39.062	Loss
Other_Aur_AURKA_ST	P04637	TP53	O14965	AURKA	S183	S185R	185	Missense	proximal	2	no	41.241	40.035	EPSD	COSMIC	39.062	Down-regulation
Other_Aur_AURKA_ST	P04637	TP53	O14965	AURKA	S183	S183L	183	Missense	central	0	yes	41.241	0.000	EPSD	COSMIC	39.062	Loss
Other_Aur_AURKA_ST	P04637	TP53	O14965	AURKA	S183	R181L	181	Missense	proximal	-2	no	41.241	31.520	EPSD	COSMIC	39.062	Loss
Other_Aur_AURKA_ST	P04637	TP53	O14965	AURKA	S183	H178P	178	Missense	distal	-5	no	41.241	41.272	EPSD	COSMIC	39.062	Up-regulation
Other_Aur_AURKA_ST	P04637	TP53	O14965	AURKA	S183	D186N	186	Missense	distal	3	no	41.241	36.755	EPSD	COSMIC	39.062	Loss
Other_Aur_AURKA_ST	P04637	TP53	O14965	AURKA	S183	A189S	189	Missense	distal	6	no	41.241	41.233	EPSD	COSMIC	39.062	Down-regulation
Other_Aur_AURKA_ST	P04637	TP53	O14965	AURKA	S183	H178L	178	Missense	distal	-5	no	41.241	41.284	EPSD	COSMIC	39.062	Up-regulation
Other_Aur_AURKA_ST	P04637	TP53	O14965	AURKA	S183	L188V	188	Missense	distal	5	no	41.241	41.569	EPSD	COSMIC	39.062	Up-regulation
Other_Aur_AURKA_ST	P04637	TP53	O14965	AURKA	S183	A189V	189	Missense	distal	6	no	41.241	41.144	EPSD	COSMIC	39.062	Down-regulation
Other_Aur_AURKA_ST	P04637	TP53	O14965	AURKA	S183	H178Y	178	Missense	distal	-5	no	41.241	41.304	EPSD	COSMIC	39.062	Up-regulation
Other_Aur_AURKA_ST	P04637	TP53	O14965	AURKA	S183	D186E	186	Missense	distal	3	no	41.241	40.196	EPSD	COSMIC	39.062	Down-regulation
Other_Aur_AURKA_ST	P04637	TP53	O14965	AURKA	S183	C182Y	182	Missense	proximal	-1	no	41.241	40.524	EPSD	COSMIC	39.062	Down-regulation
Other_Aur_AURKA_ST	P04637	TP53	O14965	AURKA	S183	D186H	186	Missense	distal	3	no	41.241	39.155	EPSD	COSMIC	39.062	Down-regulation
Other_Aur_AURKA_ST	P04637	TP53	O14965	AURKA	S183	L188Q	188	Missense	distal	5	no	41.241	43.714	EPSD	COSMIC	39.062	Up-regulation
Other_Aur_AURKA_ST	P04637	TP53	O14965	AURKA	S183	H178N	178	Missense	distal	-5	no	41.241	41.341	EPSD	COSMIC	39.062	Up-regulation
Other_Aur_AURKA_ST	P04637	TP53	O14965	AURKA	S183	G187R	187	Missense	distal	4	no	41.241	40.431	EPSD	COSMIC;GDSC	39.062	Down-regulation
Other_Aur_AURKA_ST	P04637	TP53	O14965	AURKA	S183	C182S	182	Missense	proximal	-1	no	41.241	41.468	EPSD	COSMIC	39.062	Up-regulation
Other_Aur_AURKA_ST	P04637	TP53	O14965	AURKA	S183	P190F	190	Missense	distal	7	no	41.241	41.373	EPSD	COSMIC	39.062	Up-regulation
Other_Aur_AURKA_ST	P04637	TP53	O14965	AURKA	S183	G187C	187	Missense	distal	4	no	41.241	40.405	EPSD	COSMIC	39.062	Down-regulation
Other_Aur_AURKA_ST	P04637	TP53	O14965	AURKA	S183	S185T	185	Missense	proximal	2	no	41.241	38.097	EPSD	COSMIC	39.062	Loss
Other_Aur_AURKA_ST	P04637	TP53	O14965	AURKA	S183	P190H	190	Missense	distal	7	no	41.241	41.338	EPSD	COSMIC	39.062	Up-regulation
Other_Aur_AURKA_ST	P04637	TP53	O14965	AURKA	S183	S185N	185	Missense	proximal	2	no	41.241	40.675	EPSD	COSMIC	39.062	Down-regulation
Other_Aur_AURKA_ST	P04637	TP53	O14965	AURKA	S183	D186G	186	Missense	distal	3	no	41.241	40.080	EPSD	COSMIC	39.062	Down-regulation
Other_Aur_AURKA_ST	P04637	TP53	O14965	AURKA	S183	D186V	186	Missense	distal	3	no	41.241	38.909	EPSD	COSMIC	39.062	Loss
Other_Aur_AURKA_ST	P04637	TP53	O14965	AURKA	S183	P177I	177	Missense	distal	-6	no	41.241	34.389	EPSD	COSMIC	39.062	Loss
Other_Aur_AURKA_ST	P04637	TP53	O14965	AURKA	S183	P190A	190	Missense	distal	7	no	41.241	41.297	EPSD	COSMIC	39.062	Up-regulation
Other_Aur_AURKA_ST	P04637	TP53	O14965	AURKA	S183	S185C	185	Missense	proximal	2	no	41.241	43.189	EPSD	COSMIC	39.062	Up-regulation
Other_Aur_AURKA_ST	P04637	TP53	O14965	AURKA	S183	S185I	185	Missense	proximal	2	no	41.241	40.454	EPSD	COSMIC	39.062	Down-regulation
Other_Aur_AURKA_ST	P04637	TP53	O14965	AURKA	S183	A189P	189	Missense	distal	6	no	41.241	41.177	EPSD	COSMIC	39.062	Down-regulation
Other_Aur_AURKA_ST	P04637	TP53	O14965	AURKA	S183	E180Q	180	Missense	distal	-3	no	41.241	40.942	EPSD	COSMIC	39.062	Down-regulation
Other_Aur_AURKA_ST	P04637	TP53	O14965	AURKA	S183	R181S	181	Missense	proximal	-2	no	41.241	28.082	EPSD	COSMIC	39.062	Loss
Other_Aur_AURKA_ST	P04637	TP53	O14965	AURKA	S183	C182R	182	Missense	proximal	-1	no	41.241	41.457	EPSD	COSMIC	39.062	Up-regulation
Other_Aur_AURKA_ST	P04637	TP53	O14965	AURKA	S183	E180G	180	Missense	distal	-3	no	41.241	45.412	EPSD	COSMIC	39.062	Up-regulation
Other_Aur_AURKA_ST	P04637	TP53	O14965	AURKA	S183	L188M	188	Missense	distal	5	no	41.241	40.658	EPSD	COSMIC	39.062	Down-regulation
Other_Aur_AURKA_ST	P04637	TP53	O14965	AURKA	S183	P177F	177	Missense	distal	-6	no	41.241	36.132	EPSD	COSMIC	39.062	Loss
Other_Aur_AURKA_ST	P04637	TP53	O14965	AURKA	S183	D184E	184	Missense	proximal	1	no	41.241	39.025	EPSD	COSMIC	39.062	Loss
Other_Aur_AURKA_ST	P04637	TP53	O14965	AURKA	S183	A189G	189	Missense	distal	6	no	41.241	41.231	EPSD	COSMIC	39.062	Down-regulation
Other_Aur_AURKA_ST	P04637	TP53	O14965	AURKA	S183	R181G	181	Missense	proximal	-2	no	41.241	31.097	EPSD	COSMIC	39.062	Loss
Other_Aur_AURKA_ST	P04637	TP53	O14965	AURKA	S183	D186X	186	Missense	distal	3	no	41.241	40.059	EPSD	COSMIC	39.062	Down-regulation
Other_Aur_AURKA_ST	P04637	TP53	O14965	AURKA	S183	R181Y	181	Missense	proximal	-2	no	41.241	27.365	EPSD	COSMIC	39.062	Loss
Other_Aur_AURKA_ST	P04637	TP53	O14965	AURKA	S183	D184G	184	Missense	proximal	1	no	41.241	39.564	EPSD	COSMIC	39.062	Down-regulation
Other_Aur_AURKA_ST	P04637	TP53	O14965	AURKA	S215	R209Q	209	Missense	distal	-6	no	49.444	48.578	EPSD;PhosphoSitePlus	COSMIC	39.062	Down-regulation
Other_Aur_AURKA_ST	P04637	TP53	O14965	AURKA	S215	R209W	209	Missense	distal	-6	no	49.444	35.293	EPSD;PhosphoSitePlus	COSMIC	39.062	Loss
Other_Aur_AURKA_ST	P04637	TP53	O14965	AURKA	S215	R209P	209	Missense	distal	-6	no	49.444	47.864	EPSD;PhosphoSitePlus	COSMIC	39.062	Down-regulation
Other_Aur_AURKA_ST	P04637	TP53	O14965	AURKA	S215	R209L	209	Missense	distal	-6	no	49.444	46.884	EPSD;PhosphoSitePlus	COSMIC	39.062	Down-regulation
Other_Aur_AURKA_ST	P04637	TP53	O14965	AURKA	S215	R209G	209	Missense	distal	-6	no	49.444	45.653	EPSD;PhosphoSitePlus	COSMIC	39.062	Down-regulation
Other_Aur_AURKA_ST	P04637	TP53	O14965	AURKA	S215	R209C	209	Missense	distal	-6	no	49.444	42.396	EPSD;PhosphoSitePlus	COSMIC	39.062	Down-regulation
Other_Aur_AURKA_ST	P04637	TP53	O14965	AURKA	S215	V216A	216	Missense	proximal	1	no	49.444	49.624	EPSD;PhosphoSitePlus	COSMIC	39.062	Up-regulation
Other_Aur_AURKA_ST	P04637	TP53	O14965	AURKA	S215	V217A	217	Missense	proximal	2	no	49.444	48.012	EPSD;PhosphoSitePlus	COSMIC	39.062	Down-regulation
Other_Aur_AURKA_ST	P04637	TP53	O14965	AURKA	S215	P222S	222	Missense	distal	7	no	49.444	49.554	EPSD;PhosphoSitePlus	COSMIC	39.062	Up-regulation
Other_Aur_AURKA_ST	P04637	TP53	O14965	AURKA	S215	P219L	219	Missense	distal	4	no	49.444	49.591	EPSD;PhosphoSitePlus	COSMIC	39.062	Up-regulation
Other_Aur_AURKA_ST	P04637	TP53	O14965	AURKA	S215	V218M	218	Missense	distal	3	no	49.444	50.898	EPSD;PhosphoSitePlus	COSMIC	39.062	Up-regulation
Other_Aur_AURKA_ST	P04637	TP53	O14965	AURKA	S215	D208E	208	Missense	distal	-7	no	49.444	48.707	EPSD;PhosphoSitePlus	COSMIC	39.062	Down-regulation
Other_Aur_AURKA_ST	P04637	TP53	O14965	AURKA	S215	F212L	212	Missense	distal	-3	no	49.444	54.024	EPSD;PhosphoSitePlus	COSMIC	39.062	Up-regulation
Other_Aur_AURKA_ST	P04637	TP53	O14965	AURKA	S215	H214Q	214	Missense	proximal	-1	no	49.444	49.513	EPSD;PhosphoSitePlus	COSMIC	39.062	Up-regulation
Other_Aur_AURKA_ST	P04637	TP53	O14965	AURKA	S215	P219H	219	Missense	distal	4	no	49.444	49.636	EPSD;PhosphoSitePlus	COSMIC	39.062	Up-regulation
Other_Aur_AURKA_ST	P04637	TP53	O14965	AURKA	S215	R213W	213	Missense	proximal	-2	no	49.444	-137.264	EPSD;PhosphoSitePlus	COSMIC	39.062	Loss
Other_Aur_AURKA_ST	P04637	TP53	O14965	AURKA	S215	N210D	210	Missense	distal	-5	no	49.444	49.413	EPSD;PhosphoSitePlus	COSMIC	39.062	Down-regulation
Other_Aur_AURKA_ST	P04637	TP53	O14965	AURKA	S215	V218A	218	Missense	distal	3	no	49.444	49.566	EPSD;PhosphoSitePlus	COSMIC	39.062	Up-regulation
Other_Aur_AURKA_ST	P04637	TP53	O14965	AURKA	S215	S215C	215	Missense	central	0	yes	49.444	0.000	EPSD;PhosphoSitePlus	COSMIC;GDSC;CCLE	39.062	Loss
Other_Aur_AURKA_ST	P04637	TP53	O14965	AURKA	S215	V218L	218	Missense	distal	3	no	49.444	49.905	EPSD;PhosphoSitePlus	COSMIC;GDSC;CCLE	39.062	Up-regulation
Other_Aur_AURKA_ST	P04637	TP53	O14965	AURKA	S215	T211N	211	Missense	distal	-4	no	49.444	47.998	EPSD;PhosphoSitePlus	COSMIC	39.062	Down-regulation
Other_Aur_AURKA_ST	P04637	TP53	O14965	AURKA	S215	N210S	210	Missense	distal	-5	no	49.444	49.396	EPSD;PhosphoSitePlus	COSMIC	39.062	Down-regulation
Other_Aur_AURKA_ST	P04637	TP53	O14965	AURKA	S215	P222T	222	Missense	distal	7	no	49.444	49.490	EPSD;PhosphoSitePlus	COSMIC	39.062	Up-regulation
Other_Aur_AURKA_ST	P04637	TP53	O14965	AURKA	S215	F212I	212	Missense	distal	-3	no	49.444	53.269	EPSD;PhosphoSitePlus	COSMIC	39.062	Up-regulation
Other_Aur_AURKA_ST	P04637	TP53	O14965	AURKA	S215	N210H	210	Missense	distal	-5	no	49.444	49.344	EPSD;PhosphoSitePlus	COSMIC	39.062	Down-regulation
Other_Aur_AURKA_ST	P04637	TP53	O14965	AURKA	S215	E221G	221	Missense	distal	6	no	49.444	49.503	EPSD;PhosphoSitePlus	COSMIC	39.062	Up-regulation
Other_Aur_AURKA_ST	P04637	TP53	O14965	AURKA	S215	E221D	221	Missense	distal	6	no	49.444	49.654	EPSD;PhosphoSitePlus	COSMIC	39.062	Up-regulation
Other_Aur_AURKA_ST	P04637	TP53	O14965	AURKA	S215	V217E	217	Missense	proximal	2	no	49.444	50.351	EPSD;PhosphoSitePlus	COSMIC	39.062	Up-regulation
Other_Aur_AURKA_ST	P04637	TP53	O14965	AURKA	S215	R209T	209	Missense	distal	-6	no	49.444	48.409	EPSD;PhosphoSitePlus	COSMIC	39.062	Down-regulation
Other_Aur_AURKA_ST	P04637	TP53	O14965	AURKA	S215	P222L	222	Missense	distal	7	no	49.444	49.527	EPSD;PhosphoSitePlus	COSMIC	39.062	Up-regulation
Other_Aur_AURKA_ST	P04637	TP53	O14965	AURKA	S215	P219R	219	Missense	distal	4	no	49.444	48.966	EPSD;PhosphoSitePlus	COSMIC	39.062	Down-regulation
Other_Aur_AURKA_ST	P04637	TP53	O14965	AURKA	S215	P219S	219	Missense	distal	4	no	49.444	49.497	EPSD;PhosphoSitePlus	COSMIC	39.062	Up-regulation
Other_Aur_AURKA_ST	P04637	TP53	O14965	AURKA	S215	D208Y	208	Missense	distal	-7	no	49.444	49.904	EPSD;PhosphoSitePlus	COSMIC	39.062	Up-regulation
Other_Aur_AURKA_ST	P04637	TP53	O14965	AURKA	S215	P222Q	222	Missense	distal	7	no	49.444	49.479	EPSD;PhosphoSitePlus	COSMIC	39.062	Up-regulation
Other_Aur_AURKA_ST	P04637	TP53	O14965	AURKA	S215	P222A	222	Missense	distal	7	no	49.444	49.500	EPSD;PhosphoSitePlus	COSMIC	39.062	Up-regulation
Other_Aur_AURKA_ST	P04637	TP53	O14965	AURKA	S215	V217L	217	Missense	proximal	2	no	49.444	48.917	EPSD;PhosphoSitePlus	COSMIC	39.062	Down-regulation
Other_Aur_AURKA_ST	P04637	TP53	O14965	AURKA	S215	T211S	211	Missense	distal	-4	no	49.444	47.447	EPSD;PhosphoSitePlus	COSMIC	39.062	Down-regulation
Other_Aur_AURKA_ST	P04637	TP53	O14965	AURKA	S215	D208H	208	Missense	distal	-7	no	49.444	48.814	EPSD;PhosphoSitePlus	COSMIC	39.062	Down-regulation
Other_Aur_AURKA_ST	P04637	TP53	O14965	AURKA	S215	V217M	217	Missense	proximal	2	no	49.444	49.152	EPSD;PhosphoSitePlus	COSMIC	39.062	Down-regulation
Other_Aur_AURKA_ST	P04637	TP53	O14965	AURKA	S215	N210T	210	Missense	distal	-5	no	49.444	49.405	EPSD;PhosphoSitePlus	COSMIC	39.062	Down-regulation
Other_Aur_AURKA_ST	P04637	TP53	O14965	AURKA	S215	N210K	210	Missense	distal	-5	no	49.444	49.375	EPSD;PhosphoSitePlus	COSMIC	39.062	Down-regulation
Other_Aur_AURKA_ST	P04637	TP53	O14965	AURKA	S215	F212S	212	Missense	distal	-3	no	49.444	55.060	EPSD;PhosphoSitePlus	COSMIC	39.062	Up-regulation
Other_Aur_AURKA_ST	P04637	TP53	O14965	AURKA	S215	H214P	214	Missense	proximal	-1	no	49.444	49.650	EPSD;PhosphoSitePlus	COSMIC	39.062	Up-regulation
Other_Aur_AURKA_ST	P04637	TP53	O14965	AURKA	S215	D208I	208	Missense	distal	-7	no	49.444	49.193	EPSD;PhosphoSitePlus	COSMIC	39.062	Down-regulation
Other_Aur_AURKA_ST	P04637	TP53	O14965	AURKA	S215	P219C	219	Missense	distal	4	no	49.444	48.940	EPSD;PhosphoSitePlus	COSMIC	39.062	Down-regulation
Other_Aur_AURKA_ST	P04637	TP53	O14965	AURKA	S215	F212Y	212	Missense	distal	-3	no	49.444	51.923	EPSD;PhosphoSitePlus	COSMIC	39.062	Up-regulation
Other_Aur_AURKA_ST	P04637	TP53	O14965	AURKA	S215	Y220L	220	Missense	distal	5	no	49.444	48.145	EPSD;PhosphoSitePlus	COSMIC	39.062	Down-regulation
Other_Aur_AURKA_ST	P04637	TP53	O14965	AURKA	S215	Y220X	220	Missense	distal	5	no	49.444	50.240	EPSD;PhosphoSitePlus	COSMIC	39.062	Up-regulation
Other_Aur_AURKA_ST	P04637	TP53	O14965	AURKA	S215	H214A	214	Missense	proximal	-1	no	49.444	49.977	EPSD;PhosphoSitePlus	COSMIC	39.062	Up-regulation
Other_Aur_AURKA_ST	P04637	TP53	O14965	AURKA	S269	A276S	276	Missense	distal	7	no	39.770	39.824	EPSD	COSMIC	39.062	Up-regulation
Other_Aur_AURKA_ST	P04637	TP53	O14965	AURKA	S269	G262H	262	Missense	distal	-7	no	39.770	40.181	EPSD	COSMIC	39.062	Up-regulation
Other_Aur_AURKA_ST	P04637	TP53	O14965	AURKA	S269	N263H	263	Missense	distal	-6	no	39.770	35.425	EPSD	COSMIC	39.062	Loss
Other_Aur_AURKA_ST	P04637	TP53	O14965	AURKA	S269	G266A	266	Missense	distal	-3	no	39.770	37.071	EPSD	COSMIC	39.062	Loss
Other_Aur_AURKA_ST	P04637	TP53	O14965	AURKA	S269	S269N	269	Missense	central	0	yes	39.770	0.000	EPSD	COSMIC	39.062	Loss
Other_Aur_AURKA_ST	P04637	TP53	O14965	AURKA	S269	V274I	274	Missense	distal	5	no	39.770	41.527	EPSD	COSMIC	39.062	Up-regulation
Other_Aur_AURKA_ST	P04637	TP53	O14965	AURKA	S269	L265M	265	Missense	distal	-4	no	39.770	39.712	EPSD	COSMIC	39.062	Down-regulation
Other_Aur_AURKA_ST	P04637	TP53	O14965	AURKA	S269	F270Y	270	Missense	proximal	1	no	39.770	37.367	EPSD	COSMIC	39.062	Loss
Other_Aur_AURKA_ST	P04637	TP53	O14965	AURKA	S269	L264V	264	Missense	distal	-5	no	39.770	39.774	EPSD	COSMIC	39.062	Up-regulation
Other_Aur_AURKA_ST	P04637	TP53	O14965	AURKA	S269	S269G	269	Missense	central	0	yes	39.770	0.000	EPSD	COSMIC	39.062	Loss
Other_Aur_AURKA_ST	P04637	TP53	O14965	AURKA	S269	R273Q	273	Missense	distal	4	no	39.770	40.184	EPSD	COSMIC	39.062	Up-regulation
Other_Aur_AURKA_ST	P04637	TP53	O14965	AURKA	S269	N268H	268	Missense	proximal	-1	no	39.770	41.188	EPSD	COSMIC	39.062	Up-regulation
Other_Aur_AURKA_ST	P04637	TP53	O14965	AURKA	S269	G262D	262	Missense	distal	-7	no	39.770	40.810	EPSD	COSMIC;GDSC;CCLE	39.062	Up-regulation
Other_Aur_AURKA_ST	P04637	TP53	O14965	AURKA	S269	N263I	263	Missense	distal	-6	no	39.770	29.163	EPSD	COSMIC	39.062	Loss
Other_Aur_AURKA_ST	P04637	TP53	O14965	AURKA	S269	L264P	264	Missense	distal	-5	no	39.770	39.757	EPSD	COSMIC	39.062	Down-regulation
Other_Aur_AURKA_ST	P04637	TP53	O14965	AURKA	S269	E271P	271	Missense	proximal	2	no	39.770	38.067	EPSD	COSMIC	39.062	Loss
Other_Aur_AURKA_ST	P04637	TP53	O14965	AURKA	S269	L264R	264	Missense	distal	-5	no	39.770	39.783	EPSD	COSMIC;GDSC;CCLE	39.062	Up-regulation
Other_Aur_AURKA_ST	P04637	TP53	O14965	AURKA	S269	R273Y	273	Missense	distal	4	no	39.770	40.053	EPSD	COSMIC;CCLE	39.062	Up-regulation
Other_Aur_AURKA_ST	P04637	TP53	O14965	AURKA	S269	N263D	263	Missense	distal	-6	no	39.770	33.750	EPSD	COSMIC	39.062	Loss
Other_Aur_AURKA_ST	P04637	TP53	O14965	AURKA	S269	A276T	276	Missense	distal	7	no	39.770	39.759	EPSD	COSMIC	39.062	Down-regulation
Other_Aur_AURKA_ST	P04637	TP53	O14965	AURKA	S269	S269C	269	Missense	central	0	yes	39.770	0.000	EPSD	COSMIC	39.062	Loss
Other_Aur_AURKA_ST	P04637	TP53	O14965	AURKA	S269	L264I	264	Missense	distal	-5	no	39.770	39.777	EPSD	COSMIC	39.062	Up-regulation
Other_Aur_AURKA_ST	P04637	TP53	O14965	AURKA	S269	N268K	268	Missense	proximal	-1	no	39.770	41.250	EPSD	COSMIC	39.062	Up-regulation
Other_Aur_AURKA_ST	P04637	TP53	O14965	AURKA	S269	A276F	276	Missense	distal	7	no	39.770	39.846	EPSD	COSMIC	39.062	Up-regulation
Other_Aur_AURKA_ST	P04637	TP53	O14965	AURKA	S269	G266T	266	Missense	distal	-3	no	39.770	35.347	EPSD	COSMIC	39.062	Loss
Other_Aur_AURKA_ST	P04637	TP53	O14965	AURKA	S269	G266K	266	Missense	distal	-3	no	39.770	37.137	EPSD	COSMIC	39.062	Loss
Other_Aur_AURKA_ST	P04637	TP53	O14965	AURKA	S269	E271G	271	Missense	proximal	2	no	39.770	39.480	EPSD	COSMIC	39.062	Down-regulation
Other_Aur_AURKA_ST	P04637	TP53	O14965	AURKA	S269	L264Q	264	Missense	distal	-5	no	39.770	39.772	EPSD	COSMIC	39.062	Up-regulation
Other_Aur_AURKA_ST	P04637	TP53	O14965	AURKA	S269	S269I	269	Missense	central	0	yes	39.770	0.000	EPSD	COSMIC	39.062	Loss
Other_Aur_AURKA_ST	P04637	TP53	O14965	AURKA	S269	S269R	269	Missense	central	0	yes	39.770	0.000	EPSD	COSMIC	39.062	Loss
Other_Aur_AURKA_ST	P04637	TP53	O14965	AURKA	S269	G262R	262	Missense	distal	-7	no	39.770	41.657	EPSD	COSMIC	39.062	Up-regulation
Other_Aur_AURKA_ST	P04637	TP53	O14965	AURKA	S269	N263K	263	Missense	distal	-6	no	39.770	34.610	EPSD	COSMIC	39.062	Loss
Other_Aur_AURKA_ST	P04637	TP53	O14965	AURKA	S269	V272K	272	Missense	distal	3	no	39.770	39.661	EPSD	COSMIC	39.062	Down-regulation
Other_Aur_AURKA_ST	P04637	TP53	O14965	AURKA	S269	N268F	268	Missense	proximal	-1	no	39.770	42.682	EPSD	COSMIC	39.062	Up-regulation
Other_Aur_AURKA_ST	P04637	TP53	O14965	AURKA	S269	L265Q	265	Missense	distal	-4	no	39.770	39.888	EPSD	COSMIC	39.062	Up-regulation
Other_Aur_AURKA_ST	P04637	TP53	O14965	AURKA	S269	N268S	268	Missense	proximal	-1	no	39.770	41.609	EPSD	COSMIC	39.062	Up-regulation
Other_Aur_AURKA_ST	P04637	TP53	O14965	AURKA	S269	G262S	262	Missense	distal	-7	no	39.770	41.083	EPSD	COSMIC;GDSC	39.062	Up-regulation
Other_Aur_AURKA_ST	P04637	TP53	O14965	AURKA	S269	G266S	266	Missense	distal	-3	no	39.770	38.484	EPSD	COSMIC	39.062	Loss
Other_Aur_AURKA_ST	P04637	TP53	O14965	AURKA	S313	N310T	310	Missense	distal	-3	no	41.824	38.043	EPSD	COSMIC	39.062	Loss
Other_Aur_AURKA_ST	P04637	TP53	O14965	AURKA	S313	Q317R	317	Missense	distal	4	no	41.824	41.409	EPSD	COSMIC	39.062	Down-regulation
Other_Aur_AURKA_ST	P04637	TP53	O14965	AURKA	S313	P309S	309	Missense	distal	-4	no	41.824	43.741	EPSD	COSMIC;GDSC;CCLE	39.062	Up-regulation
Other_Aur_AURKA_ST	P04637	TP53	O14965	AURKA	S313	K319E	319	Missense	distal	6	no	41.824	41.990	EPSD	COSMIC	39.062	Up-regulation
Other_Aur_AURKA_ST	P04637	TP53	O14965	AURKA	S313	K320N	320	Missense	distal	7	no	41.824	41.807	EPSD	COSMIC;GDSC;CCLE	39.062	Down-regulation
Other_Aur_AURKA_ST	P04637	TP53	O14965	AURKA	S313	N310L	310	Missense	distal	-3	no	41.824	40.143	EPSD	COSMIC	39.062	Down-regulation
Other_Aur_AURKA_ST	P04637	TP53	O14965	AURKA	S313	T312S	312	Missense	proximal	-1	no	41.824	40.121	EPSD	COSMIC	39.062	Down-regulation
Other_Aur_AURKA_ST	P04637	TP53	O14965	AURKA	S313	N311Y	311	Missense	proximal	-2	no	41.824	38.430	EPSD	COSMIC	39.062	Loss
Other_Aur_AURKA_ST	P04637	TP53	O14965	AURKA	S313	R306P	306	Missense	distal	-7	no	41.824	43.110	EPSD	COSMIC	39.062	Up-regulation
Other_Aur_AURKA_ST	P04637	TP53	O14965	AURKA	S313	A307T	307	Missense	distal	-6	no	41.824	41.603	EPSD	COSMIC	39.062	Down-regulation
Other_Aur_AURKA_ST	P04637	TP53	O14965	AURKA	S313	N311K	311	Missense	proximal	-2	no	41.824	45.802	EPSD	COSMIC	39.062	Up-regulation
Other_Aur_AURKA_ST	P04637	TP53	O14965	AURKA	S313	Q317K	317	Missense	distal	4	no	41.824	42.385	EPSD	COSMIC	39.062	Up-regulation
Other_Aur_AURKA_ST	P04637	TP53	O14965	AURKA	S313	S315P	315	Missense	proximal	2	no	41.824	40.576	EPSD	COSMIC	39.062	Down-regulation
Other_Aur_AURKA_ST	P04637	TP53	O14965	AURKA	S313	N310H	310	Missense	distal	-3	no	41.824	41.886	EPSD	COSMIC	39.062	Up-regulation
Other_Aur_AURKA_ST	P04637	TP53	O14965	AURKA	S313	R306Q	306	Missense	distal	-7	no	41.824	41.301	EPSD	COSMIC	39.062	Down-regulation
Other_Aur_AURKA_ST	P04637	TP53	O14965	AURKA	S313	S314C	314	Missense	proximal	1	no	41.824	39.910	EPSD	COSMIC	39.062	Down-regulation
Other_Aur_AURKA_ST	P04637	TP53	O14965	AURKA	S313	P318A	318	Missense	distal	5	no	41.824	42.185	EPSD	COSMIC	39.062	Up-regulation
Other_Aur_AURKA_ST	P04637	TP53	O14965	AURKA	S313	P316L	316	Missense	distal	3	no	41.824	41.360	EPSD	COSMIC	39.062	Down-regulation
Other_Aur_AURKA_ST	P04637	TP53	O14965	AURKA	S313	L308M	308	Missense	distal	-5	no	41.824	41.851	EPSD	COSMIC	39.062	Up-regulation
Other_Aur_AURKA_ST	P04637	TP53	O14965	AURKA	S313	S313C	313	Missense	central	0	yes	41.824	0.000	EPSD	COSMIC	39.062	Loss
Other_Aur_AURKA_ST	P04637	TP53	O14965	AURKA	S313	N311H	311	Missense	proximal	-2	no	41.824	45.068	EPSD	COSMIC	39.062	Up-regulation
Other_Aur_AURKA_ST	P04637	TP53	O14965	AURKA	S313	L308V	308	Missense	distal	-5	no	41.824	41.828	EPSD	COSMIC	39.062	Up-regulation
Other_Aur_AURKA_ST	P04637	TP53	O14965	AURKA	S313	S314F	314	Missense	proximal	1	no	41.824	48.304	EPSD	COSMIC	39.062	Up-regulation
Other_Aur_AURKA_ST	P04637	TP53	O14965	AURKA	S313	K319R	319	Missense	distal	6	no	41.824	42.032	EPSD	COSMIC	39.062	Up-regulation
Other_Aur_AURKA_ST	P04637	TP53	O14965	AURKA	S313	T312A	312	Missense	proximal	-1	no	41.824	40.234	EPSD	COSMIC	39.062	Down-regulation
Other_Aur_AURKA_ST	P04637	TP53	O14965	AURKA	S313	N310D	310	Missense	distal	-3	no	41.824	37.169	EPSD	COSMIC	39.062	Loss
Other_Aur_AURKA_ST	P04637	TP53	O14965	AURKA	S313	N311D	311	Missense	proximal	-2	no	41.824	43.644	EPSD	COSMIC	39.062	Up-regulation
Other_Aur_AURKA_ST	P04637	TP53	O14965	AURKA	S313	P309R	309	Missense	distal	-4	no	41.824	42.940	EPSD	COSMIC	39.062	Up-regulation
Other_Aur_AURKA_ST	P04637	TP53	O14965	AURKA	S313	S313N	313	Missense	central	0	yes	41.824	0.000	EPSD	COSMIC	39.062	Loss
Other_Aur_AURKA_ST	P04637	TP53	O14965	AURKA	S313	Q317P	317	Missense	distal	4	no	41.824	41.888	EPSD	COSMIC	39.062	Up-regulation
Other_Aur_AURKA_ST	P04637	TP53	O14965	AURKA	S313	A307S	307	Missense	distal	-6	no	41.824	41.608	EPSD	COSMIC	39.062	Down-regulation
Other_Aur_AURKA_ST	P04637	TP53	O14965	AURKA	S313	P316S	316	Missense	distal	3	no	41.824	42.475	EPSD	COSMIC	39.062	Up-regulation
Other_Aur_AURKA_ST	P04637	TP53	O14965	AURKA	S315	N310T	310	Missense	distal	-5	no	43.992	43.953	EPSD;PhosphoSitePlus	COSMIC	39.062	Down-regulation
Other_Aur_AURKA_ST	P04637	TP53	O14965	AURKA	S315	Q317R	317	Missense	proximal	2	no	43.992	41.992	EPSD;PhosphoSitePlus	COSMIC	39.062	Down-regulation
Other_Aur_AURKA_ST	P04637	TP53	O14965	AURKA	S315	P309S	309	Missense	distal	-6	no	43.992	44.542	EPSD;PhosphoSitePlus	COSMIC;GDSC;CCLE	39.062	Up-regulation
Other_Aur_AURKA_ST	P04637	TP53	O14965	AURKA	S315	K319E	319	Missense	distal	4	no	43.992	44.008	EPSD;PhosphoSitePlus	COSMIC	39.062	Up-regulation
Other_Aur_AURKA_ST	P04637	TP53	O14965	AURKA	S315	P322L	322	Missense	distal	7	no	43.992	44.075	EPSD;PhosphoSitePlus	COSMIC	39.062	Up-regulation
Other_Aur_AURKA_ST	P04637	TP53	O14965	AURKA	S315	K320N	320	Missense	distal	5	no	43.992	43.069	EPSD;PhosphoSitePlus	COSMIC;GDSC;CCLE	39.062	Down-regulation
Other_Aur_AURKA_ST	P04637	TP53	O14965	AURKA	S315	N310L	310	Missense	distal	-5	no	43.992	43.936	EPSD;PhosphoSitePlus	COSMIC	39.062	Down-regulation
Other_Aur_AURKA_ST	P04637	TP53	O14965	AURKA	S315	T312S	312	Missense	distal	-3	no	43.992	47.129	EPSD;PhosphoSitePlus	COSMIC	39.062	Up-regulation
Other_Aur_AURKA_ST	P04637	TP53	O14965	AURKA	S315	N311Y	311	Missense	distal	-4	no	43.992	43.495	EPSD;PhosphoSitePlus	COSMIC	39.062	Down-regulation
Other_Aur_AURKA_ST	P04637	TP53	O14965	AURKA	S315	P322R	322	Missense	distal	7	no	43.992	44.084	EPSD;PhosphoSitePlus	COSMIC	39.062	Up-regulation
Other_Aur_AURKA_ST	P04637	TP53	O14965	AURKA	S315	N311K	311	Missense	distal	-4	no	43.992	44.349	EPSD;PhosphoSitePlus	COSMIC	39.062	Up-regulation
Other_Aur_AURKA_ST	P04637	TP53	O14965	AURKA	S315	Q317K	317	Missense	proximal	2	no	43.992	40.588	EPSD;PhosphoSitePlus	COSMIC	39.062	Down-regulation
Other_Aur_AURKA_ST	P04637	TP53	O14965	AURKA	S315	S315P	315	Missense	central	0	yes	43.992	0.000	EPSD;PhosphoSitePlus	COSMIC	39.062	Loss
Other_Aur_AURKA_ST	P04637	TP53	O14965	AURKA	S315	N310H	310	Missense	distal	-5	no	43.992	43.892	EPSD;PhosphoSitePlus	COSMIC	39.062	Down-regulation
Other_Aur_AURKA_ST	P04637	TP53	O14965	AURKA	S315	S314C	314	Missense	proximal	-1	no	43.992	43.765	EPSD;PhosphoSitePlus	COSMIC	39.062	Down-regulation
Other_Aur_AURKA_ST	P04637	TP53	O14965	AURKA	S315	P318A	318	Missense	distal	3	no	43.992	43.190	EPSD;PhosphoSitePlus	COSMIC	39.062	Down-regulation
Other_Aur_AURKA_ST	P04637	TP53	O14965	AURKA	S315	P316L	316	Missense	proximal	1	no	43.992	48.642	EPSD;PhosphoSitePlus	COSMIC	39.062	Up-regulation
Other_Aur_AURKA_ST	P04637	TP53	O14965	AURKA	S315	L308M	308	Missense	distal	-7	no	43.992	44.124	EPSD;PhosphoSitePlus	COSMIC	39.062	Up-regulation
Other_Aur_AURKA_ST	P04637	TP53	O14965	AURKA	S315	S313C	313	Missense	proximal	-2	no	43.992	41.854	EPSD;PhosphoSitePlus	COSMIC	39.062	Down-regulation
Other_Aur_AURKA_ST	P04637	TP53	O14965	AURKA	S315	N311H	311	Missense	distal	-4	no	43.992	38.205	EPSD;PhosphoSitePlus	COSMIC	39.062	Loss
Other_Aur_AURKA_ST	P04637	TP53	O14965	AURKA	S315	L308V	308	Missense	distal	-7	no	43.992	43.822	EPSD;PhosphoSitePlus	COSMIC	39.062	Down-regulation
Other_Aur_AURKA_ST	P04637	TP53	O14965	AURKA	S315	S314F	314	Missense	proximal	-1	no	43.992	45.065	EPSD;PhosphoSitePlus	COSMIC	39.062	Up-regulation
Other_Aur_AURKA_ST	P04637	TP53	O14965	AURKA	S315	K319R	319	Missense	distal	4	no	43.992	43.017	EPSD;PhosphoSitePlus	COSMIC	39.062	Down-regulation
Other_Aur_AURKA_ST	P04637	TP53	O14965	AURKA	S315	T312A	312	Missense	distal	-3	no	43.992	45.716	EPSD;PhosphoSitePlus	COSMIC	39.062	Up-regulation
Other_Aur_AURKA_ST	P04637	TP53	O14965	AURKA	S315	N310D	310	Missense	distal	-5	no	43.992	43.961	EPSD;PhosphoSitePlus	COSMIC	39.062	Down-regulation
Other_Aur_AURKA_ST	P04637	TP53	O14965	AURKA	S315	N311D	311	Missense	distal	-4	no	43.992	39.936	EPSD;PhosphoSitePlus	COSMIC	39.062	Down-regulation
Other_Aur_AURKA_ST	P04637	TP53	O14965	AURKA	S315	P309R	309	Missense	distal	-6	no	43.992	45.572	EPSD;PhosphoSitePlus	COSMIC	39.062	Up-regulation
Other_Aur_AURKA_ST	P04637	TP53	O14965	AURKA	S315	S313N	313	Missense	proximal	-2	no	43.992	46.668	EPSD;PhosphoSitePlus	COSMIC	39.062	Up-regulation
Other_Aur_AURKA_ST	P04637	TP53	O14965	AURKA	S315	Q317P	317	Missense	proximal	2	no	43.992	41.950	EPSD;PhosphoSitePlus	COSMIC	39.062	Down-regulation
Other_Aur_AURKA_ST	P04637	TP53	O14965	AURKA	S315	P316S	316	Missense	proximal	1	no	43.992	42.992	EPSD;PhosphoSitePlus	COSMIC	39.062	Down-regulation
Other_Aur_AURKA_ST	Q8IX03	WWC1	O14965	AURKA	S270	Q276R	276	Missense	distal	6	no	40.751	40.795	EPSD	COSMIC	39.062	Up-regulation
Other_Aur_AURKA_ST	Q8IX03	WWC1	O14965	AURKA	S270	P272R	272	Missense	proximal	2	no	40.751	40.793	EPSD	COSMIC	39.062	Up-regulation
Other_Aur_AURKA_ST	Q8IX03	WWC1	O14965	AURKA	S626	A628P	628	Missense	proximal	2	no	43.745	44.381	EPSD	COSMIC	39.062	Up-regulation
Other_Aur_AURKA_ST	Q8IX03	WWC1	O14965	AURKA	S876	E873K	873	Missense	distal	-3	no	42.717	44.256	EPSD	COSMIC	39.062	Up-regulation
Other_Aur_AURKA_ST	Q8IX03	WWC1	O14965	AURKA	S876	D869H	869	Missense	distal	-7	no	42.717	42.088	EPSD	COSMIC	39.062	Down-regulation
Other_Aur_AURKA_ST	Q8IX03	WWC1	O14965	AURKA	S876	G881E	881	Missense	distal	5	no	42.717	42.623	EPSD	COSMIC	39.062	Down-regulation
Other_Aur_AURKA_ST	Q8IX03	WWC1	O14965	AURKA	S876	G881V	881	Missense	distal	5	no	42.717	41.699	EPSD	COSMIC	39.062	Down-regulation
Other_Aur_AURKA_ST	Q8IX03	WWC1	O14965	AURKA	T912	P913S	913	Missense	proximal	1	no	41.443	40.443	EPSD	COSMIC	39.062	Down-regulation
Other_Aur_AURKA_ST	Q8IX03	WWC1	O14965	AURKA	S922	K928Q	928	Missense	distal	6	no	43.693	43.858	EPSD	COSMIC	39.062	Up-regulation
Other_Aur_AURKA_ST	Q8IX03	WWC1	O14965	AURKA	S945	T951I	951	Missense	distal	6	no	40.984	41.153	EPSD	COSMIC	39.062	Up-regulation
Other_Aur_AURKA_ST	Q8IX03	WWC1	O14965	AURKA	S947	T951I	951	Missense	distal	4	no	37.718	39.320	EPSD	COSMIC	39.062	Gain
Other_Aur_AURKA_ST	Q8IX03	WWC1	O14965	AURKA	S962	R966P	966	Missense	distal	4	no	39.988	40.466	EPSD	COSMIC	39.062	Up-regulation
Other_Aur_AURKA_ST	Q8IX03	WWC1	O14965	AURKA	S978	S981F	981	Missense	distal	3	no	54.263	54.317	EPSD	COSMIC	39.062	Up-regulation
Other_Aur_AURKA_ST	Q8IX03	WWC1	O14965	AURKA	S978	S981L	981	Missense	distal	3	no	54.263	53.148	EPSD	COSMIC	39.062	Down-regulation
Other_Aur_AURKA_ST	P10275	AR	O14965	AURKA	T219	S220F	220	Missense	proximal	1	no	34.765	41.245	EPSD	COSMIC	39.062	Gain
Other_Aur_AURKA_ST	P10275	AR	O14965	AURKA	S244	K241R	241	Missense	distal	-3	no	32.005	39.831	EPSD	COSMIC	39.062	Gain
Other_Aur_AURKA_ST	P10275	AR	O14965	AURKA	T282	R280H	280	Missense	proximal	-2	no	46.920	39.682	PhosphoSitePlus;EPSD	COSMIC	39.062	Down-regulation
Other_Aur_AURKA_ST	P10275	AR	O14965	AURKA	T282	E289G	289	Missense	distal	7	no	46.920	46.991	PhosphoSitePlus;EPSD	COSMIC	39.062	Up-regulation
Other_Aur_AURKA_ST	P10275	AR	O14965	AURKA	T282	P276S	276	Missense	distal	-6	no	46.920	47.470	PhosphoSitePlus;EPSD	COSMIC	39.062	Up-regulation
Other_Aur_AURKA_ST	P10275	AR	O14965	AURKA	T282	P283S	283	Missense	proximal	1	no	46.920	45.920	PhosphoSitePlus;EPSD	COSMIC	39.062	Down-regulation
Other_Aur_AURKA_ST	P10275	AR	O14965	AURKA	T282	A278T	278	Missense	distal	-4	no	46.920	51.879	PhosphoSitePlus;EPSD	COSMIC	39.062	Up-regulation
Other_Aur_AURKA_ST	P10275	AR	O14965	AURKA	T282	A285D	285	Missense	distal	3	no	46.920	49.130	PhosphoSitePlus;EPSD	COSMIC	39.062	Up-regulation
Other_Aur_AURKA_ST	P10275	AR	O14965	AURKA	T282	A278V	278	Missense	distal	-4	no	46.920	50.595	PhosphoSitePlus;EPSD	COSMIC	39.062	Up-regulation
Other_Aur_AURKA_ST	P10275	AR	O14965	AURKA	T282	A285V	285	Missense	distal	3	no	46.920	46.798	PhosphoSitePlus;EPSD	COSMIC	39.062	Down-regulation
Other_Aur_AURKA_ST	P10275	AR	O14965	AURKA	S293	E289G	289	Missense	distal	-4	no	46.780	44.944	EPSD;PhosphoSitePlus	COSMIC	39.062	Down-regulation
Other_Aur_AURKA_ST	P10275	AR	O14965	AURKA	S293	G300D	300	Missense	distal	7	no	46.780	46.733	EPSD;PhosphoSitePlus	COSMIC	39.062	Down-regulation
Other_Aur_AURKA_ST	P10275	AR	O14965	AURKA	S293	S298R	298	Missense	distal	5	no	46.780	45.628	EPSD;PhosphoSitePlus	COSMIC	39.062	Down-regulation
Other_Aur_AURKA_ST	P10275	AR	O14965	AURKA	S293	D297Y	297	Missense	distal	4	no	46.780	46.324	EPSD;PhosphoSitePlus	COSMIC	39.062	Down-regulation
Other_Aur_AURKA_ST	P10275	AR	O14965	AURKA	S293	D296G	296	Missense	distal	3	no	46.780	45.619	EPSD;PhosphoSitePlus	COSMIC	39.062	Down-regulation
Other_Aur_AURKA_ST	P10275	AR	O14965	AURKA	S293	D296E	296	Missense	distal	3	no	46.780	45.736	EPSD;PhosphoSitePlus	COSMIC	39.062	Down-regulation
Other_Aur_AURKA_ST	P10275	AR	O14965	AURKA	S293	G292S	292	Missense	proximal	-1	no	46.780	46.721	EPSD;PhosphoSitePlus	COSMIC	39.062	Down-regulation
Other_Aur_AURKA_ST	P10275	AR	O14965	AURKA	S298	G300D	300	Missense	proximal	2	no	39.510	40.570	EPSD	COSMIC	39.062	Up-regulation
Other_Aur_AURKA_ST	P10275	AR	O14965	AURKA	S298	D305N	305	Missense	distal	7	no	39.510	39.359	EPSD	COSMIC	39.062	Down-regulation
Other_Aur_AURKA_ST	P10275	AR	O14965	AURKA	S298	S298R	298	Missense	central	0	yes	39.510	0.000	EPSD	COSMIC	39.062	Loss
Other_Aur_AURKA_ST	P10275	AR	O14965	AURKA	S298	D297Y	297	Missense	proximal	-1	no	39.510	37.244	EPSD	COSMIC	39.062	Loss
Other_Aur_AURKA_ST	P10275	AR	O14965	AURKA	S298	D296G	296	Missense	proximal	-2	no	39.510	38.028	EPSD	COSMIC	39.062	Loss
Other_Aur_AURKA_ST	P10275	AR	O14965	AURKA	S298	E304K	304	Missense	distal	6	no	39.510	39.344	EPSD	COSMIC	39.062	Down-regulation
Other_Aur_AURKA_ST	P10275	AR	O14965	AURKA	S298	D296E	296	Missense	proximal	-2	no	39.510	27.526	EPSD	COSMIC	39.062	Loss
Other_Aur_AURKA_ST	P10275	AR	O14965	AURKA	S298	G292S	292	Missense	distal	-6	no	39.510	42.271	EPSD	COSMIC	39.062	Up-regulation
Other_Aur_AURKA_ST	P10275	AR	O14965	AURKA	S336	G329C	329	Missense	distal	-7	no	39.251	39.931	EPSD	COSMIC;GDSC;CCLE	39.062	Up-regulation
Other_Aur_AURKA_ST	P10275	AR	O14965	AURKA	S336	E340Q	340	Missense	distal	4	no	39.251	38.673	EPSD	COSMIC	39.062	Loss
Other_Aur_AURKA_ST	P10275	AR	O14965	AURKA	S336	T338I	338	Missense	proximal	2	no	39.251	41.608	EPSD	COSMIC;CCLE	39.062	Up-regulation
Other_Aur_AURKA_ST	P10275	AR	O14965	AURKA	S792	G796E	796	Missense	distal	4	no	40.139	40.321	EPSD	COSMIC	39.062	Up-regulation
Other_Aur_AURKA_ST	P10275	AR	O14965	AURKA	S792	L798P	798	Missense	distal	6	no	40.139	40.146	EPSD	COSMIC	39.062	Up-regulation
Other_Aur_AURKA_ST	P10275	AR	O14965	AURKA	S792	Q799E	799	Missense	distal	7	no	40.139	40.263	EPSD	COSMIC	39.062	Up-regulation
Other_Aur_AURKA_ST	P10275	AR	O14965	AURKA	S792	S792F	792	Missense	central	0	yes	40.139	0.000	EPSD	COSMIC	39.062	Loss
Other_Aur_AURKA_ST	P10275	AR	O14965	AURKA	S792	E794G	794	Missense	proximal	2	no	40.139	39.849	EPSD	COSMIC	39.062	Down-regulation
Other_Aur_AURKA_ST	P10275	AR	O14965	AURKA	S792	S792P	792	Missense	central	0	yes	40.139	0.000	EPSD	COSMIC	39.062	Loss
Other_Aur_AURKA_ST	P10275	AR	O14965	AURKA	S792	H790Q	790	Missense	proximal	-2	no	40.139	36.738	EPSD	COSMIC	39.062	Loss
Other_Aur_AURKA_ST	P10275	AR	O14965	AURKA	S792	E794D	794	Missense	proximal	2	no	40.139	40.909	EPSD	COSMIC	39.062	Up-regulation
Other_Aur_AURKA_ST	O15360	FANCA	O14965	AURKA	S165	R163C	163	Missense	proximal	-2	no	47.693	32.396	PhosphoSitePlus	COSMIC	39.062	Loss
Other_Aur_AURKA_ST	O15360	FANCA	O14965	AURKA	S165	R163H	163	Missense	proximal	-2	no	47.693	40.454	PhosphoSitePlus	COSMIC	39.062	Down-regulation
Other_Aur_AURKA_ST	O15360	FANCA	O14965	AURKA	S165	K172E	172	Missense	distal	7	no	47.693	47.804	PhosphoSitePlus	COSMIC	39.062	Up-regulation
Other_Aur_AURKA_ST	O15360	FANCA	O14965	AURKA	S165	E169A	169	Missense	distal	4	no	47.693	47.266	PhosphoSitePlus	COSMIC	39.062	Down-regulation
Other_Aur_AURKA_ST	O15360	FANCA	O14965	AURKA	S165	H158Y	158	Missense	distal	-7	no	47.693	48.782	PhosphoSitePlus	COSMIC	39.062	Up-regulation
Other_Aur_AURKA_ST	O15360	FANCA	O14965	AURKA	S165	S165F	165	Missense	central	0	yes	47.693	0.000	PhosphoSitePlus	COSMIC	39.062	Loss
Other_Aur_AURKA_ST	O15360	FANCA	O14965	AURKA	S165	M160I	160	Missense	distal	-5	no	47.693	47.673	PhosphoSitePlus	COSMIC	39.062	Down-regulation
Other_Aur_AURKA_ST	O15360	FANCA	O14965	AURKA	S309	T306R	306	Missense	distal	-3	no	37.059	46.675	EPSD	COSMIC	39.062	Gain
Other_Aur_AURKA_ST	O15360	FANCA	O14965	AURKA	S1149	S1149P	1149	Missense	central	0	yes	51.498	0.000	EPSD	COSMIC	39.062	Loss
Other_Aur_AURKA_ST	O15360	FANCA	O14965	AURKA	S1149	L1143V	1143	Missense	distal	-6	no	51.498	52.408	EPSD	COSMIC;GDSC	39.062	Up-regulation
Other_Aur_AURKA_ST	O15360	FANCA	O14965	AURKA	S1149	R1144Q	1144	Missense	distal	-5	no	51.498	51.487	EPSD	COSMIC;GDSC;CCLE	39.062	Down-regulation
Other_Aur_AURKA_ST	O15360	FANCA	O14965	AURKA	S1149	S1149F	1149	Missense	central	0	yes	51.498	0.000	EPSD	COSMIC	39.062	Loss
Other_Aur_AURKA_ST	O15360	FANCA	O14965	AURKA	S1301	I1300M	1300	Missense	proximal	-1	no	48.087	46.712	EPSD	COSMIC	39.062	Down-regulation
Other_Aur_AURKA_ST	O15360	FANCA	O14965	AURKA	S1301	K1299N	1299	Missense	proximal	-2	no	48.087	44.108	EPSD	COSMIC	39.062	Down-regulation
Other_Aur_AURKA_ST	O15360	FANCA	O14965	AURKA	S1374	D1372N	1372	Missense	proximal	-2	no	40.044	38.224	EPSD	COSMIC	39.062	Loss
Other_Aur_AURKA_ST	O15360	FANCA	O14965	AURKA	S1374	T1373I	1373	Missense	proximal	-1	no	40.044	39.836	EPSD	COSMIC	39.062	Down-regulation
Other_Aur_AURKA_ST	O15360	FANCA	O14965	AURKA	S1374	D1372G	1372	Missense	proximal	-2	no	40.044	38.563	EPSD	COSMIC	39.062	Loss
Other_Aur_AURKA_ST	O15360	FANCA	O14965	AURKA	S1374	A1370S	1370	Missense	distal	-4	no	40.044	43.006	EPSD	COSMIC	39.062	Up-regulation
Other_Aur_AURKA_ST	P53667	LIMK1	O14965	AURKA	S196	E194K	194	Missense	proximal	-2	no	27.687	41.830	EPSD	COSMIC	39.062	Gain
Other_Aur_AURKA_ST	P53667	LIMK1	O14965	AURKA	S210	G207R	207	Missense	distal	-3	no	35.951	41.145	EPSD	COSMIC	39.062	Gain
Other_Aur_AURKA_ST	P53667	LIMK1	O14965	AURKA	S287	S286I	286	Missense	proximal	-1	no	38.991	40.485	EPSD	COSMIC	39.062	Gain
Other_Aur_AURKA_ST	P53667	LIMK1	O14965	AURKA	S287	S281N	281	Missense	distal	-6	no	38.991	42.196	EPSD	COSMIC;GDSC;CCLE	39.062	Gain
Other_Aur_AURKA_ST	P53667	LIMK1	O14965	AURKA	S298	R295W	295	Missense	distal	-3	no	41.520	-37.652	EPSD	COSMIC	39.062	Loss
Other_Aur_AURKA_ST	P53667	LIMK1	O14965	AURKA	S337	G342R	342	Missense	distal	5	no	39.376	38.123	EPSD	COSMIC	39.062	Loss
Other_Aur_AURKA_ST	P53667	LIMK1	O14965	AURKA	S337	G342V	342	Missense	distal	5	no	39.376	38.359	EPSD	COSMIC	39.062	Loss
Other_Aur_AURKA_ST	P53667	LIMK1	O14965	AURKA	S337	I340N	340	Missense	distal	3	no	39.376	35.215	EPSD	COSMIC	39.062	Loss
Other_Aur_AURKA_ST	P53667	LIMK1	O14965	AURKA	S337	P336T	336	Missense	proximal	-1	no	39.376	41.293	EPSD	COSMIC	39.062	Up-regulation
Other_Aur_AURKA_ST	Q9BXS6	NUSAP1	O14965	AURKA	S215	N214S	214	Missense	proximal	-1	no	39.568	41.407	EPSD	COSMIC	39.062	Up-regulation
Other_Aur_AURKA_ST	Q9BXS6	NUSAP1	O14965	AURKA	S215	Q221R	221	Missense	distal	6	no	39.568	39.611	EPSD	COSMIC	39.062	Up-regulation
Other_Aur_AURKA_ST	Q9BXS6	NUSAP1	O14965	AURKA	S243	R249C	249	Missense	distal	6	no	42.899	42.729	EPSD	COSMIC	39.062	Down-regulation
Other_Aur_AURKA_ST	Q9BXS6	NUSAP1	O14965	AURKA	S243	R250C	250	Missense	distal	7	no	42.899	42.940	EPSD	COSMIC	39.062	Up-regulation
Other_Aur_AURKA_ST	Q9BXS6	NUSAP1	O14965	AURKA	S251	R249C	249	Missense	proximal	-2	no	43.033	27.736	EPSD	COSMIC	39.062	Loss
Other_Aur_AURKA_ST	Q9BXS6	NUSAP1	O14965	AURKA	S251	R254Q	254	Missense	distal	3	no	43.033	43.422	EPSD	COSMIC	39.062	Up-regulation
Other_Aur_AURKA_ST	Q9BXS6	NUSAP1	O14965	AURKA	S251	R250C	250	Missense	proximal	-1	no	43.033	42.817	EPSD	COSMIC	39.062	Down-regulation
Other_Aur_AURKA_ST	Q9BXS6	NUSAP1	O14965	AURKA	S251	Q252P	252	Missense	proximal	1	no	43.033	39.922	EPSD	COSMIC;GDSC;CCLE	39.062	Down-regulation
Other_Aur_AURKA_ST	Q9BXS6	NUSAP1	O14965	AURKA	S269	S276F	276	Missense	distal	7	no	42.009	42.031	EPSD	COSMIC	39.062	Up-regulation
Other_Aur_AURKA_ST	Q9BXS6	NUSAP1	O14965	AURKA	S276	T280M	280	Missense	distal	4	no	38.153	40.047	EPSD	COSMIC	39.062	Gain
Other_Aur_AURKA_ST	Q9BXS6	NUSAP1	O14965	AURKA	S285	T280M	280	Missense	distal	-5	no	46.790	46.799	EPSD	COSMIC	39.062	Up-regulation
Other_Aur_AURKA_ST	Q9BXS6	NUSAP1	O14965	AURKA	S285	D290H	290	Missense	distal	5	no	46.790	45.211	EPSD	COSMIC	39.062	Down-regulation
Other_Aur_AURKA_ST	Q9BXS6	NUSAP1	O14965	AURKA	S296	D290H	290	Missense	distal	-6	no	39.557	41.233	EPSD	COSMIC	39.062	Up-regulation
Other_Aur_AURKA_ST	Q9BXS6	NUSAP1	O14965	AURKA	T309	V308M	308	Missense	proximal	-1	no	43.538	44.815	EPSD	COSMIC	39.062	Up-regulation
Other_Aur_AURKA_ST	Q9BXS6	NUSAP1	O14965	AURKA	T309	S305T	305	Missense	distal	-4	no	43.538	45.534	EPSD	COSMIC	39.062	Up-regulation
Other_Aur_AURKA_ST	Q9BXS6	NUSAP1	O14965	AURKA	T347	E345K	345	Missense	proximal	-2	no	25.429	39.572	EPSD	COSMIC	39.062	Gain
Other_Aur_AURKA_ST	P49450	CENPA	O14965	AURKA	S32	S32F	32	Missense	central	0	yes	45.951	0.000	EPSD	COSMIC	39.062	Loss
Other_Aur_AURKA_ST	P49450	CENPA	O14965	AURKA	S32	S37F	37	Missense	distal	5	no	45.951	46.662	EPSD	COSMIC	39.062	Up-regulation
Other_Aur_AURKA_ST	P49450	CENPA	O14965	AURKA	S32	H38N	38	Missense	distal	6	no	45.951	45.708	EPSD	COSMIC	39.062	Down-regulation
Other_Aur_AURKA_ST	P49450	CENPA	O14965	AURKA	S36	S37F	37	Missense	proximal	1	no	33.744	40.224	EPSD	COSMIC	39.062	Gain
Other_Aur_AURKA_ST	Q9NS23	RASSF1	O14965	AURKA	S179	P181S	181	Missense	proximal	2	no	41.817	43.065	EPSD	COSMIC;GDSC;CCLE	39.062	Up-regulation
Other_Aur_AURKA_ST	Q9NS23	RASSF1	O14965	AURKA	S179	P177S	177	Missense	proximal	-2	no	41.817	43.718	EPSD	COSMIC	39.062	Up-regulation
Other_Aur_AURKA_ST	Q9NS23	RASSF1	O14965	AURKA	S179	S179R	179	Missense	central	0	yes	41.817	0.000	EPSD	COSMIC	39.062	Loss
Other_Aur_AURKA_ST	Q9NS23	RASSF1	O14965	AURKA	S179	R176C	176	Missense	distal	-3	no	41.817	37.280	EPSD	COSMIC;GDSC	39.062	Loss
Other_Aur_AURKA_ST	Q9NS23	RASSF1	O14965	AURKA	S179	S183R	183	Missense	distal	4	no	41.817	41.286	EPSD	COSMIC	39.062	Down-regulation
Other_Aur_AURKA_ST	Q9NS23	RASSF1	O14965	AURKA	S179	R176H	176	Missense	distal	-3	no	41.817	36.044	EPSD	COSMIC	39.062	Loss
Other_Aur_AURKA_ST	Q9NS23	RASSF1	O14965	AURKA	S188	P181S	181	Missense	distal	-7	no	40.145	38.285	EPSD	COSMIC;GDSC;CCLE	39.062	Loss
Other_Aur_AURKA_ST	Q9NS23	RASSF1	O14965	AURKA	S188	R193W	193	Missense	distal	5	no	40.145	41.144	EPSD	COSMIC	39.062	Up-regulation
Other_Aur_AURKA_ST	Q9NS23	RASSF1	O14965	AURKA	S188	A192V	192	Missense	distal	4	no	40.145	39.851	EPSD	COSMIC	39.062	Down-regulation
Other_Aur_AURKA_ST	Q9NS23	RASSF1	O14965	AURKA	S188	L189Q	189	Missense	proximal	1	no	40.145	38.606	EPSD	COSMIC	39.062	Loss
Other_Aur_AURKA_ST	Q9NS23	RASSF1	O14965	AURKA	S188	S183R	183	Missense	distal	-5	no	40.145	40.150	EPSD	COSMIC	39.062	Up-regulation
Other_Aur_AURKA_ST	Q9NS23	RASSF1	O14965	AURKA	S188	R194Q	194	Missense	distal	6	no	40.145	40.101	EPSD	COSMIC	39.062	Down-regulation
Other_Aur_AURKA_ST	Q9NS23	RASSF1	O14965	AURKA	S201	R205H	205	Missense	distal	4	no	42.544	43.214	EPSD	COSMIC;CCLE	39.062	Up-regulation
Other_Aur_AURKA_ST	Q9NS23	RASSF1	O14965	AURKA	S201	T200I	200	Missense	proximal	-1	no	42.544	42.336	EPSD	COSMIC	39.062	Down-regulation
Other_Aur_AURKA_ST	Q9NS23	RASSF1	O14965	AURKA	S201	G197R	197	Missense	distal	-4	no	42.544	42.863	EPSD	COSMIC	39.062	Up-regulation
Other_Aur_AURKA_ST	Q9NS23	RASSF1	O14965	AURKA	S201	R194Q	194	Missense	distal	-7	no	42.544	42.022	EPSD	COSMIC	39.062	Down-regulation
Other_Aur_AURKA_ST	Q9NS23	RASSF1	O14965	AURKA	T206	R205H	205	Missense	proximal	-1	no	48.585	48.176	EPSD	COSMIC;CCLE	39.062	Down-regulation
Other_Aur_AURKA_ST	Q9NS23	RASSF1	O14965	AURKA	T206	T200I	200	Missense	distal	-6	no	48.585	41.188	EPSD	COSMIC	39.062	Down-regulation
Other_Aur_AURKA_ST	Q9NS23	RASSF1	O14965	AURKA	S207	R205H	205	Missense	proximal	-2	no	58.455	51.217	EPSD	COSMIC;CCLE	39.062	Down-regulation
Other_Aur_AURKA_ST	Q9NS23	RASSF1	O14965	AURKA	S207	T200I	200	Missense	distal	-7	no	58.455	58.505	EPSD	COSMIC	39.062	Up-regulation
Other_Aur_AURKA_ST	P49736	MCM2	O14965	AURKA	T158	R151H	151	Missense	distal	-7	no	43.684	42.208	EPSD	COSMIC	39.062	Down-regulation
Other_Aur_AURKA_ST	P49736	MCM2	O14965	AURKA	T158	T158M	158	Missense	central	0	yes	43.684	0.000	EPSD	COSMIC	39.062	Loss
Other_Aur_AURKA_ST	P49736	MCM2	O14965	AURKA	T158	E155G	155	Missense	distal	-3	no	43.684	47.855	EPSD	COSMIC	39.062	Up-regulation
Other_Aur_AURKA_ST	P49736	MCM2	O14965	AURKA	S220	R227H	227	Missense	distal	7	no	55.596	55.601	PhosphoSitePlus	COSMIC;GDSC;CCLE	39.062	Up-regulation
Other_Aur_AURKA_ST	P49736	MCM2	O14965	AURKA	S220	R218C	218	Missense	proximal	-2	no	55.596	40.299	PhosphoSitePlus	COSMIC;GDSC;CCLE	39.062	Down-regulation
Other_Aur_AURKA_ST	P49736	MCM2	O14965	AURKA	S229	R227H	227	Missense	proximal	-2	no	45.165	37.926	EPSD	COSMIC;GDSC;CCLE	39.062	Loss
Other_Aur_AURKA_ST	P49736	MCM2	O14965	AURKA	S229	E235K	235	Missense	distal	6	no	45.165	44.999	EPSD	COSMIC	39.062	Down-regulation
Other_Aur_AURKA_ST	P49736	MCM2	O14965	AURKA	S541	Y535C	535	Missense	distal	-6	no	43.974	39.839	EPSD	COSMIC	39.062	Down-regulation
Other_Aur_AURKA_ST	P49736	MCM2	O14965	AURKA	S541	R542Q	542	Missense	proximal	1	no	43.974	44.865	EPSD	COSMIC	39.062	Up-regulation
Other_Aur_AURKA_ST	P49736	MCM2	O14965	AURKA	S754	S754F	754	Missense	central	0	yes	43.194	0.000	EPSD	COSMIC	39.062	Loss
Other_Aur_AURKA_ST	P49736	MCM2	O14965	AURKA	S754	A756V	756	Missense	proximal	2	no	43.194	44.626	EPSD	COSMIC;GDSC	39.062	Up-regulation
Other_Aur_AURKA_ST	O75496	GMNN	O14965	AURKA	S34	R40K	40	Missense	distal	6	no	41.875	41.667	EPSD	COSMIC	39.062	Down-regulation
Other_Aur_AURKA_ST	O75496	GMNN	O14965	AURKA	S45	R40K	40	Missense	distal	-5	no	40.010	39.985	EPSD	COSMIC	39.062	Down-regulation
Other_Aur_AURKA_ST	P11233	RALA	O14965	AURKA	S129	V125A	125	Missense	distal	-4	no	40.238	36.563	EPSD	COSMIC	39.062	Loss
Other_Aur_AURKA_ST	Q9Y6A5	TACC3	O14965	AURKA	S34	K41R	41	Missense	distal	7	no	51.131	51.175	EPSD	COSMIC	39.062	Up-regulation
Other_Aur_AURKA_ST	Q9Y6A5	TACC3	O14965	AURKA	S39	K41R	41	Missense	proximal	2	no	40.106	41.510	EPSD	COSMIC	39.062	Up-regulation
Other_Aur_AURKA_ST	Q9Y6A5	TACC3	O14965	AURKA	T87	A80T	80	Missense	distal	-7	no	47.660	47.202	EPSD	COSMIC	39.062	Down-regulation
Other_Aur_AURKA_ST	Q9Y6A5	TACC3	O14965	AURKA	T196	S190F	190	Missense	distal	-6	no	41.851	36.193	EPSD	COSMIC;GDSC;CCLE	39.062	Loss
Other_Aur_AURKA_ST	Q9Y6A5	TACC3	O14965	AURKA	S402	P395L	395	Missense	distal	-7	no	46.420	44.747	EPSD	COSMIC	39.062	Down-regulation
Other_Aur_AURKA_ST	Q9Y6A5	TACC3	O14965	AURKA	S402	R400Q	400	Missense	proximal	-2	no	46.420	35.780	EPSD	COSMIC	39.062	Loss
Other_Aur_AURKA_ST	Q9Y6A5	TACC3	O14965	AURKA	S570	D569H	569	Missense	proximal	-1	no	48.144	46.401	EPSD	COSMIC	39.062	Down-regulation
Other_Aur_AURKA_ST	Q9Y6A5	TACC3	O14965	AURKA	S570	R568K	568	Missense	proximal	-2	no	48.144	41.640	EPSD	COSMIC;GDSC;CCLE	39.062	Down-regulation
Other_Aur_AURKA_ST	P25490	YY1	O14965	AURKA	T39	E37D	37	Missense	proximal	-2	no	30.912	42.896	EPSD	COSMIC	39.062	Gain
Other_Aur_AURKA_ST	P25490	YY1	O14965	AURKA	S252	P249S	249	Missense	distal	-3	no	42.387	44.567	EPSD	COSMIC	39.062	Up-regulation
Other_Aur_AURKA_ST	P25490	YY1	O14965	AURKA	S252	E253K	253	Missense	proximal	1	no	42.387	44.411	EPSD	COSMIC	39.062	Up-regulation
Other_Aur_AURKA_ST	P25490	YY1	O14965	AURKA	S365	T372R	372	Missense	distal	7	no	45.539	45.585	PhosphoSitePlus	COSMIC	39.062	Up-regulation
Other_Aur_AURKA_ST	P25490	YY1	O14965	AURKA	S365	G361E	361	Missense	distal	-4	no	45.539	47.375	PhosphoSitePlus	COSMIC	39.062	Up-regulation
Other_Aur_AURKA_ST	P25490	YY1	O14965	AURKA	S365	N369S	369	Missense	distal	4	no	45.539	46.414	PhosphoSitePlus	COSMIC	39.062	Up-regulation
Other_Aur_AURKA_ST	P30305	CDC25B	O14965	AURKA	T58	P51L	51	Missense	distal	-7	no	41.017	39.344	EPSD	COSMIC	39.062	Down-regulation
Other_Aur_AURKA_ST	P30305	CDC25B	O14965	AURKA	T58	Q57R	57	Missense	proximal	-1	no	41.017	41.358	EPSD	COSMIC	39.062	Up-regulation
Other_Aur_AURKA_ST	P30305	CDC25B	O14965	AURKA	T86	R93W	93	Missense	distal	7	no	39.121	39.326	EPSD	COSMIC	39.062	Up-regulation
Other_Aur_AURKA_ST	P30305	CDC25B	O14965	AURKA	T86	S83I	83	Missense	distal	-3	no	39.121	37.330	EPSD	COSMIC	39.062	Loss
Other_Aur_AURKA_ST	P30305	CDC25B	O14965	AURKA	T86	R82C	82	Missense	distal	-4	no	39.121	35.920	EPSD	COSMIC	39.062	Loss
Other_Aur_AURKA_ST	P30305	CDC25B	O14965	AURKA	T86	R80L	80	Missense	distal	-6	no	39.121	36.560	EPSD	COSMIC	39.062	Loss
Other_Aur_AURKA_ST	P30305	CDC25B	O14965	AURKA	T86	S89P	89	Missense	distal	3	no	39.121	38.469	EPSD	COSMIC	39.062	Loss
Other_Aur_AURKA_ST	P30305	CDC25B	O14965	AURKA	S89	R93W	93	Missense	distal	4	no	42.061	43.014	EPSD	COSMIC	39.062	Up-regulation
Other_Aur_AURKA_ST	P30305	CDC25B	O14965	AURKA	S89	S83I	83	Missense	distal	-6	no	42.061	34.659	EPSD	COSMIC	39.062	Loss
Other_Aur_AURKA_ST	P30305	CDC25B	O14965	AURKA	S89	R82C	82	Missense	distal	-7	no	42.061	40.854	EPSD	COSMIC	39.062	Down-regulation
Other_Aur_AURKA_ST	P30305	CDC25B	O14965	AURKA	S89	S89P	89	Missense	central	0	yes	42.061	0.000	EPSD	COSMIC	39.062	Loss
Other_Aur_AURKA_ST	P30305	CDC25B	O14965	AURKA	S115	A109V	109	Missense	distal	-6	no	43.504	42.668	EPSD	COSMIC	39.062	Down-regulation
Other_Aur_AURKA_ST	P30305	CDC25B	O14965	AURKA	S178	A184V	184	Missense	distal	6	no	47.032	46.935	EPSD	COSMIC	39.062	Down-regulation
Other_Aur_AURKA_ST	P30305	CDC25B	O14965	AURKA	S178	R175Q	175	Missense	distal	-3	no	47.032	37.368	EPSD	COSMIC;GDSC	39.062	Loss
Other_Aur_AURKA_ST	P30305	CDC25B	O14965	AURKA	S178	S178N	178	Missense	central	0	yes	47.032	0.000	EPSD	COSMIC;GDSC;CCLE	39.062	Loss
Other_Aur_AURKA_ST	P30305	CDC25B	O14965	AURKA	S182	A184V	184	Missense	proximal	2	no	42.157	43.589	EPSD	COSMIC	39.062	Up-regulation
Other_Aur_AURKA_ST	P30305	CDC25B	O14965	AURKA	S182	S188R	188	Missense	distal	6	no	42.157	42.138	EPSD	COSMIC	39.062	Down-regulation
Other_Aur_AURKA_ST	P30305	CDC25B	O14965	AURKA	S182	R175Q	175	Missense	distal	-7	no	42.157	41.634	EPSD	COSMIC;GDSC	39.062	Down-regulation
Other_Aur_AURKA_ST	P30305	CDC25B	O14965	AURKA	S182	S178N	178	Missense	distal	-4	no	42.157	42.707	EPSD	COSMIC;GDSC;CCLE	39.062	Up-regulation
Other_Aur_AURKA_ST	P30305	CDC25B	O14965	AURKA	S187	S188R	188	Missense	proximal	1	no	36.303	39.523	EPSD	COSMIC	39.062	Gain
Other_Aur_AURKA_ST	P30305	CDC25B	O14965	AURKA	S229	S230F	230	Missense	proximal	1	no	34.681	41.161	EPSD	COSMIC	39.062	Gain
Other_Aur_AURKA_ST	P30305	CDC25B	O14965	AURKA	S353	R352Q	352	Missense	proximal	-1	no	50.158	49.818	PhosphoSitePlus	COSMIC	39.062	Down-regulation
Other_Aur_AURKA_ST	P30305	CDC25B	O14965	AURKA	S353	R350T	350	Missense	distal	-3	no	50.158	40.542	PhosphoSitePlus	COSMIC	39.062	Down-regulation
Other_Aur_AURKA_ST	P30305	CDC25B	O14965	AURKA	S375	S373N	373	Missense	proximal	-2	no	39.179	41.855	EPSD	COSMIC	39.062	Up-regulation
Other_Aur_AURKA_ST	P30305	CDC25B	O14965	AURKA	S375	R372C	372	Missense	distal	-3	no	39.179	34.642	EPSD	COSMIC	39.062	Loss
Other_Aur_AURKA_ST	P30305	CDC25B	O14965	AURKA	S375	V370I	370	Missense	distal	-5	no	39.179	39.182	EPSD	COSMIC;GDSC;CCLE	39.062	Up-regulation
Other_Aur_AURKA_ST	P30305	CDC25B	O14965	AURKA	S375	E380K	380	Missense	distal	5	no	39.179	39.706	EPSD	COSMIC	39.062	Up-regulation
Other_Aur_AURKA_ST	P30305	CDC25B	O14965	AURKA	S513	D510N	510	Missense	distal	-3	no	35.422	40.077	EPSD	COSMIC	39.062	Gain
Atypical_GTF2F1_GTF2F1_ST	P35269	GTF2F1	P35269	GTF2F1	S261	D255N	255	Missense	distal	-6	no	1.938	1.905	EPSD	COSMIC	1.654	Down-regulation
Atypical_GTF2F1_GTF2F1_ST	P35269	GTF2F1	P35269	GTF2F1	S261	E259K	259	Missense	proximal	-2	no	1.938	1.754	EPSD	COSMIC	1.654	Down-regulation
Atypical_GTF2F1_GTF2F1_ST	P35269	GTF2F1	P35269	GTF2F1	S385	N384S	384	Missense	proximal	-1	no	7.288	7.154	PhosphoSitePlus;EPSD	COSMIC	1.654	Down-regulation
Atypical_GTF2F1_GTF2F1_ST	P35269	GTF2F1	P35269	GTF2F1	S385	R382S	382	Missense	distal	-3	no	7.288	7.313	PhosphoSitePlus;EPSD	COSMIC	1.654	Up-regulation
Atypical_GTF2F1_GTF2F1_ST	P35269	GTF2F1	P35269	GTF2F1	S385	T389M	389	Missense	distal	4	no	7.288	7.280	PhosphoSitePlus;EPSD	COSMIC	1.654	Down-regulation
Atypical_GTF2F1_GTF2F1_ST	P35269	GTF2F1	P35269	GTF2F1	T389	N384S	384	Missense	distal	-5	no	8.110	8.012	EPSD;PhosphoSitePlus	COSMIC	1.654	Down-regulation
Atypical_GTF2F1_GTF2F1_ST	P35269	GTF2F1	P35269	GTF2F1	T389	R382S	382	Missense	distal	-7	no	8.110	8.049	EPSD;PhosphoSitePlus	COSMIC	1.654	Down-regulation
Atypical_GTF2F1_GTF2F1_ST	P35269	GTF2F1	P35269	GTF2F1	T389	T389M	389	Missense	central	0	yes	8.110	0.000	EPSD;PhosphoSitePlus	COSMIC	1.654	Loss
Atypical_GTF2F1_GTF2F1_ST	P35269	GTF2F1	P35269	GTF2F1	S436	L432M	432	Missense	distal	-4	no	2.034	2.068	EPSD	COSMIC;GDSC;CCLE	1.654	Up-regulation
Atypical_GTF2F1_GTF2F1_ST	P35269	GTF2F1	P35269	GTF2F1	S436	S436L	436	Missense	central	0	yes	2.034	0.000	EPSD	COSMIC	1.654	Loss
Atypical_GTF2F1_GTF2F1_ST	P35269	GTF2F1	P35269	GTF2F1	S442	S449N	449	Missense	distal	7	no	2.096	2.108	EPSD	COSMIC	1.654	Up-regulation
Atypical_GTF2F1_GTF2F1_ST	P35269	GTF2F1	P35269	GTF2F1	S442	T446I	446	Missense	distal	4	no	2.096	2.089	EPSD	COSMIC	1.654	Down-regulation
Atypical_GTF2F1_GTF2F1_ST	P35269	GTF2F1	P35269	GTF2F1	S442	S436L	436	Missense	distal	-6	no	2.096	2.008	EPSD	COSMIC	1.654	Down-regulation
Atypical_GTF2F1_GTF2F1_ST	P35269	GTF2F1	P35269	GTF2F1	T445	S449N	449	Missense	distal	4	no	2.314	2.271	EPSD	COSMIC	1.654	Down-regulation
Atypical_GTF2F1_GTF2F1_ST	P35269	GTF2F1	P35269	GTF2F1	T445	T446I	446	Missense	proximal	1	no	2.314	2.317	EPSD	COSMIC	1.654	Up-regulation
Atypical_GTF2F1_GTF2F1_ST	P35269	GTF2F1	P35269	GTF2F1	T445	G450S	450	Missense	distal	5	no	2.314	1.566	EPSD	COSMIC	1.654	Loss
Atypical_GTF2F1_GTF2F1_ST	P13631	RARG	P35269	GTF2F1	S36	P37L	37	Missense	proximal	1	no	1.963	0.153	EPSD	COSMIC	1.654	Loss
Atypical_GTF2F1_GTF2F1_ST	P13631	RARG	P35269	GTF2F1	S43	P37L	37	Missense	distal	-6	no	3.549	3.491	EPSD	COSMIC	1.654	Down-regulation
Atypical_GTF2F1_GTF2F1_ST	P13631	RARG	P35269	GTF2F1	S43	L49P	49	Missense	distal	6	no	3.549	3.375	EPSD	COSMIC	1.654	Down-regulation
Atypical_GTF2F1_GTF2F1_ST	P13631	RARG	P35269	GTF2F1	S43	F46V	46	Missense	distal	3	no	3.549	3.528	EPSD	COSMIC	1.654	Down-regulation
Atypical_GTF2F1_GTF2F1_ST	P13631	RARG	P35269	GTF2F1	S76	E72K	72	Missense	distal	-4	no	2.128	1.966	EPSD	COSMIC	1.654	Down-regulation
Atypical_GTF2F1_GTF2F1_ST	P13631	RARG	P35269	GTF2F1	S76	P82S	82	Missense	distal	6	no	2.128	2.204	EPSD	COSMIC	1.654	Up-regulation
Atypical_GTF2F1_GTF2F1_ST	P13631	RARG	P35269	GTF2F1	S76	P83L	83	Missense	distal	7	no	2.128	2.152	EPSD	COSMIC	1.654	Up-regulation
Atypical_GTF2F1_GTF2F1_ST	P13631	RARG	P35269	GTF2F1	S77	E72K	72	Missense	distal	-5	no	8.594	8.591	EPSD;PhosphoSitePlus	COSMIC	1.654	Down-regulation
Atypical_GTF2F1_GTF2F1_ST	P13631	RARG	P35269	GTF2F1	S77	P82S	82	Missense	distal	5	no	8.594	6.485	EPSD;PhosphoSitePlus	COSMIC	1.654	Down-regulation
Atypical_GTF2F1_GTF2F1_ST	P13631	RARG	P35269	GTF2F1	S77	P83L	83	Missense	distal	6	no	8.594	8.768	EPSD;PhosphoSitePlus	COSMIC	1.654	Up-regulation
Atypical_GTF2F1_GTF2F1_ST	P13631	RARG	P35269	GTF2F1	S79	V86I	86	Missense	distal	7	no	7.873	7.864	PhosphoSitePlus;EPSD	COSMIC	1.654	Down-regulation
Atypical_GTF2F1_GTF2F1_ST	P13631	RARG	P35269	GTF2F1	S79	E72K	72	Missense	distal	-7	no	7.873	7.902	PhosphoSitePlus;EPSD	COSMIC	1.654	Up-regulation
Atypical_GTF2F1_GTF2F1_ST	P13631	RARG	P35269	GTF2F1	S79	P82S	82	Missense	distal	3	no	7.873	7.514	PhosphoSitePlus;EPSD	COSMIC	1.654	Down-regulation
Atypical_GTF2F1_GTF2F1_ST	P13631	RARG	P35269	GTF2F1	S79	P83L	83	Missense	distal	4	no	7.873	7.687	PhosphoSitePlus;EPSD	COSMIC	1.654	Down-regulation
Atypical_GTF2F1_GTF2F1_ST	P13631	RARG	P35269	GTF2F1	S79	R85Q	85	Missense	distal	6	no	7.873	7.902	PhosphoSitePlus;EPSD	COSMIC	1.654	Up-regulation
Atypical_GTF2F1_GTF2F1_ST	P13631	RARG	P35269	GTF2F1	S426	G430S	430	Missense	distal	4	no	2.052	2.025	EPSD	COSMIC;GDSC;CCLE	1.654	Down-regulation
AGC_NDR_LATS_LATS1_ST	Q9NQS7	INCENP	O95835	LATS1	S50	S50N	50	Missense	central	0	yes	0.003	0.000	EPSD	COSMIC	0.001	Loss
AGC_NDR_LATS_LATS1_ST	Q9NQS7	INCENP	O95835	LATS1	S97	R92Q	92	Missense	distal	-5	no	0.001	0.000	EPSD	COSMIC	0.001	Loss
AGC_NDR_LATS_LATS1_ST	Q9NQS7	INCENP	O95835	LATS1	S300	R297H	297	Missense	distal	-3	no	0.003	0.001	EPSD	COSMIC	0.001	Down-regulation
AGC_NDR_LATS_LATS1_ST	Q9NQS7	INCENP	O95835	LATS1	S302	R297H	297	Missense	distal	-5	no	0.001	0.002	EPSD	COSMIC	0.001	Up-regulation
AGC_NDR_LATS_LATS1_ST	Q9NQS7	INCENP	O95835	LATS1	S336	R333C	333	Missense	distal	-3	no	0.003	0.000	EPSD	COSMIC	0.001	Loss
AGC_NDR_LATS_LATS1_ST	Q9NQS7	INCENP	O95835	LATS1	S446	R441K	441	Missense	distal	-5	no	0.001	0.000	EPSD	COSMIC	0.001	Loss
AGC_NDR_LATS_LATS1_ST	Q9NQS7	INCENP	O95835	LATS1	T498	R493W	493	Missense	distal	-5	no	0.001	0.000	EPSD	COSMIC	0.001	Loss
AGC_NDR_LATS_LATS1_ST	Q9NQS7	INCENP	O95835	LATS1	S518	S518Y	518	Missense	central	0	yes	0.001	0.000	EPSD	COSMIC	0.001	Loss
AGC_NDR_LATS_LATS1_ST	Q9NQS7	INCENP	O95835	LATS1	S518	S518F	518	Missense	central	0	yes	0.001	0.000	EPSD	COSMIC	0.001	Loss
AGC_NDR_LATS_LATS1_ST	P46937	YAP1	O95835	LATS1	S105	K102R	102	Missense	distal	-3	no	0.000	0.003	EPSD	COSMIC	0.001	Gain
AGC_NDR_LATS_LATS1_ST	P46937	YAP1	O95835	LATS1	S109	R106G	106	Missense	distal	-3	no	0.005	0.002	EPSD;PhosphoSitePlus	COSMIC	0.001	Down-regulation
AGC_NDR_LATS_LATS1_ST	P46937	YAP1	O95835	LATS1	S127	S127F	127	Missense	central	0	yes	0.005	0.000	EPSD;PhosphoSitePlus	COSMIC	0.001	Loss
AGC_NDR_LATS_LATS1_ST	P46937	YAP1	O95835	LATS1	S138	Q133H	133	Missense	distal	-5	no	0.000	0.002	EPSD	COSMIC	0.001	Gain
AGC_NDR_LATS_LATS1_ST	P46937	YAP1	O95835	LATS1	T378	T378I	378	Missense	central	0	yes	0.002	0.000	EPSD	COSMIC	0.001	Loss
AGC_NDR_LATS_LATS1_ST	P46937	YAP1	O95835	LATS1	T378	T378M	378	Missense	central	0	yes	0.002	0.000	EPSD	COSMIC	0.001	Loss
AGC_NDR_LATS_LATS1_ST	P46937	YAP1	O95835	LATS1	S388	D383H	383	Missense	distal	-5	no	0.000	0.002	EPSD	COSMIC	0.001	Gain
AGC_NDR_LATS_LATS1_ST	P46937	YAP1	O95835	LATS1	S432	D427H	427	Missense	distal	-5	no	0.000	0.002	EPSD	COSMIC	0.001	Gain
AGC_NDR_LATS_LATS1_ST	Q8NHZ8	CDC26	O95835	LATS1	T7	R4Q	4	Missense	distal	-3	no	0.003	0.000	PhosphoSitePlus	COSMIC	0.001	Loss
AGC_NDR_LATS_LATS1_ST	O95835	LATS1	O95835	LATS1	S204	A199T	199	Missense	distal	-5	no	0.000	0.001	EPSD	COSMIC	0.001	Gain
AGC_NDR_LATS_LATS1_ST	O95835	LATS1	O95835	LATS1	T255	R252I	252	Missense	distal	-3	no	0.003	0.000	EPSD	COSMIC	0.001	Loss
AGC_NDR_LATS_LATS1_ST	O95835	LATS1	O95835	LATS1	T255	T255N	255	Missense	central	0	yes	0.003	0.000	EPSD	COSMIC	0.001	Loss
AGC_NDR_LATS_LATS1_ST	O95835	LATS1	O95835	LATS1	T262	R259K	259	Missense	distal	-3	no	0.003	0.000	EPSD	COSMIC	0.001	Loss
AGC_NDR_LATS_LATS1_ST	O95835	LATS1	O95835	LATS1	S286	P292S	292	Missense	distal	6	no	0.000	0.001	EPSD	COSMIC	0.001	Gain
AGC_NDR_LATS_LATS1_ST	O95835	LATS1	O95835	LATS1	S596	S593R	593	Missense	distal	-3	no	0.000	0.003	EPSD	COSMIC	0.001	Gain
AGC_NDR_LATS_LATS1_ST	O95835	LATS1	O95835	LATS1	S792	G787R	787	Missense	distal	-5	no	0.000	0.001	EPSD	COSMIC	0.001	Gain
AGC_NDR_LATS_LATS1_ST	O95835	LATS1	O95835	LATS1	S859	R854T	854	Missense	distal	-5	no	0.001	0.000	EPSD	COSMIC	0.001	Loss
AGC_NDR_LATS_LATS1_ST	O95835	LATS1	O95835	LATS1	S909	R904Q	904	Missense	distal	-5	no	0.001	0.000	EPSD;PhosphoSitePlus	COSMIC;CCLE	0.001	Loss
AGC_NDR_LATS_LATS1_ST	O95835	LATS1	O95835	LATS1	S909	S909Y	909	Missense	central	0	yes	0.001	0.000	EPSD;PhosphoSitePlus	COSMIC	0.001	Loss
AGC_NDR_LATS_LATS1_ST	P04049	RAF1	O95835	LATS1	T10	Q5H	5	Missense	distal	-5	no	-0.001	0.001	EPSD	COSMIC	0.001	Gain
AGC_NDR_LATS_LATS1_ST	P04049	RAF1	O95835	LATS1	S188	S188N	188	Missense	central	0	yes	0.001	0.000	EPSD	COSMIC	0.001	Loss
AGC_NDR_LATS_LATS1_ST	P04049	RAF1	O95835	LATS1	S188	M183T	183	Missense	distal	-5	no	0.001	0.000	EPSD	COSMIC	0.001	Loss
AGC_NDR_LATS_LATS1_ST	P04049	RAF1	O95835	LATS1	S188	S188R	188	Missense	central	0	yes	0.001	0.000	EPSD	COSMIC	0.001	Loss
AGC_NDR_LATS_LATS1_ST	P04049	RAF1	O95835	LATS1	S247	S244R	244	Missense	distal	-3	no	-0.001	0.003	EPSD	COSMIC	0.001	Gain
AGC_NDR_LATS_LATS1_ST	P04049	RAF1	O95835	LATS1	S259	S259A	259	Missense	central	0	yes	0.004	0.000	PhosphoSitePlus	COSMIC	0.001	Loss
AGC_NDR_LATS_LATS1_ST	P04049	RAF1	O95835	LATS1	S259	S259C	259	Missense	central	0	yes	0.004	0.000	PhosphoSitePlus	COSMIC	0.001	Loss
AGC_NDR_LATS_LATS1_ST	P04049	RAF1	O95835	LATS1	S259	S259P	259	Missense	central	0	yes	0.004	0.000	PhosphoSitePlus	COSMIC	0.001	Loss
AGC_NDR_LATS_LATS1_ST	P04049	RAF1	O95835	LATS1	S267	N262K	262	Missense	distal	-5	no	0.000	0.001	EPSD	COSMIC	0.001	Gain
AGC_NDR_LATS_LATS1_ST	P04049	RAF1	O95835	LATS1	S285	R282Q	282	Missense	distal	-3	no	0.003	0.000	EPSD	COSMIC	0.001	Loss
AGC_NDR_LATS_LATS1_ST	P04049	RAF1	O95835	LATS1	S285	S285F	285	Missense	central	0	yes	0.003	0.000	EPSD	COSMIC	0.001	Loss
AGC_NDR_LATS_LATS1_ST	P04049	RAF1	O95835	LATS1	S287	R282Q	282	Missense	distal	-5	no	0.001	0.000	EPSD	COSMIC	0.001	Loss
AGC_NDR_LATS_LATS1_ST	P04049	RAF1	O95835	LATS1	S289	S289L	289	Missense	central	0	yes	0.002	0.000	EPSD	COSMIC	0.001	Loss
AGC_NDR_LATS_LATS1_ST	P04049	RAF1	O95835	LATS1	S296	S291L	291	Missense	distal	-5	no	0.000	0.001	EPSD	COSMIC	0.001	Gain
AGC_NDR_LATS_LATS1_ST	P04049	RAF1	O95835	LATS1	S306	S301R	301	Missense	distal	-5	no	0.000	0.001	EPSD	COSMIC	0.001	Gain
AGC_NDR_LATS_LATS1_ST	P04049	RAF1	O95835	LATS1	S338	R333C	333	Missense	distal	-5	no	0.001	0.000	EPSD	COSMIC	0.001	Loss
AGC_NDR_LATS_LATS1_ST	P04049	RAF1	O95835	LATS1	S359	S359C	359	Missense	central	0	yes	0.001	0.000	EPSD	COSMIC	0.001	Loss
AGC_NDR_LATS_LATS1_ST	P04049	RAF1	O95835	LATS1	S604	Q601R	601	Missense	distal	-3	no	0.000	0.003	EPSD	COSMIC	0.001	Gain
AGC_NDR_LATS_LATS1_ST	P04049	RAF1	O95835	LATS1	S621	R618L	618	Missense	distal	-3	no	0.003	0.000	EPSD	COSMIC	0.001	Loss
AGC_NDR_LATS_LATS1_ST	P04049	RAF1	O95835	LATS1	S621	R618Q	618	Missense	distal	-3	no	0.003	0.000	EPSD	COSMIC	0.001	Loss
AGC_NDR_LATS_LATS1_ST	Q02241	KIF23	O95835	LATS1	S605	R602Q	602	Missense	distal	-3	no	0.003	0.000	EPSD	COSMIC	0.001	Loss
AGC_NDR_LATS_LATS1_ST	Q02241	KIF23	O95835	LATS1	S692	P687H	687	Missense	distal	-5	no	0.000	0.001	EPSD	COSMIC	0.001	Gain
AGC_NDR_LATS_LATS1_ST	Q02241	KIF23	O95835	LATS1	S812	H809Q	809	Missense	distal	-3	no	0.001	0.000	EPSD	COSMIC	0.001	Loss
AGC_NDR_LATS_LATS1_ST	Q02241	KIF23	O95835	LATS1	S812	S812L	812	Missense	central	0	yes	0.001	0.000	EPSD	COSMIC	0.001	Loss
AGC_NDR_LATS_LATS1_ST	Q02241	KIF23	O95835	LATS1	S814	H809Q	809	Missense	distal	-5	no	0.005	0.003	PhosphoSitePlus;EPSD	COSMIC	0.001	Down-regulation
AGC_NDR_LATS_LATS1_ST	Q02241	KIF23	O95835	LATS1	S912	R907Q	907	Missense	distal	-5	no	0.004	0.003	EPSD	COSMIC	0.001	Down-regulation
AGC_NDR_LATS_LATS1_ST	Q4VCS5	AMOT	O95835	LATS1	S175	S175G	175	Missense	central	0	yes	0.005	0.000	PhosphoSitePlus	COSMIC	0.001	Loss
AGC_NDR_LATS_LATS1_ST	Q4VCS5	AMOT	O95835	LATS1	T806	H801N	801	Missense	distal	-5	no	0.001	-0.001	EPSD	COSMIC	0.001	Loss
AGC_NDR_LATS_LATS1_ST	Q4VCS5	AMOT	O95835	LATS1	S863	S863I	863	Missense	central	0	yes	0.003	0.000	EPSD	COSMIC	0.001	Loss
AGC_NDR_LATS_LATS1_ST	Q4VCS5	AMOT	O95835	LATS1	S1041	R1039L	1039	Missense	proximal	-2	no	0.000	0.001	EPSD	COSMIC	0.001	Gain
AGC_NDR_LATS_LATS1_ST	Q4VCS5	AMOT	O95835	LATS1	S1044	R1039H	1039	Missense	distal	-5	no	0.000	0.001	EPSD	COSMIC	0.001	Gain
AGC_NDR_LATS_LATS1_ST	Q9GZV5	WWTR1	O95835	LATS1	S5	N2H	2	Missense	distal	-3	no	0.000	0.001	EPSD	COSMIC	0.001	Gain
AGC_NDR_LATS_LATS1_ST	Q9GZV5	WWTR1	O95835	LATS1	S51	L48R	48	Missense	distal	-3	no	0.000	0.003	EPSD	COSMIC	0.001	Gain
AGC_NDR_LATS_LATS1_ST	Q9GZV5	WWTR1	O95835	LATS1	S66	R63C	63	Missense	distal	-3	no	0.005	0.002	EPSD	COSMIC	0.001	Down-regulation
AGC_NDR_LATS_LATS1_ST	Q9GZV5	WWTR1	O95835	LATS1	S89	S89A	89	Missense	central	0	yes	0.005	0.000	PhosphoSitePlus	COSMIC	0.001	Loss
AGC_NDR_LATS_LATS1_ST	Q9GZV5	WWTR1	O95835	LATS1	S117	R114C	114	Missense	distal	-3	no	0.005	0.002	EPSD	COSMIC	0.001	Down-regulation
AGC_NDR_LATS_LATS1_ST	Q9GZV5	WWTR1	O95835	LATS1	S117	R114H	114	Missense	distal	-3	no	0.005	0.002	EPSD	COSMIC;CCLE	0.001	Down-regulation
TK_PDGFR_PDGFRB_Y	P09619	PDGFRB	P09619	PDGFRB	Y562	E563Q	563	Missense	proximal	1	no	62.833	65.524	EPSD;PhosphoSitePlus	COSMIC	43.065	Up-regulation
TK_PDGFR_PDGFRB_Y	P09619	PDGFRB	P09619	PDGFRB	Y562	W566C	566	Missense	distal	4	no	62.833	62.826	EPSD;PhosphoSitePlus	COSMIC	43.065	Down-regulation
TK_PDGFR_PDGFRB_Y	P09619	PDGFRB	P09619	PDGFRB	Y562	R561P	561	Missense	proximal	-1	no	62.833	69.592	EPSD;PhosphoSitePlus	COSMIC	43.065	Up-regulation
TK_PDGFR_PDGFRB_Y	P09619	PDGFRB	P09619	PDGFRB	Y562	W566L	566	Missense	distal	4	no	62.833	62.744	EPSD;PhosphoSitePlus	COSMIC	43.065	Down-regulation
TK_PDGFR_PDGFRB_Y	P09619	PDGFRB	P09619	PDGFRB	Y562	Y562C	562	Missense	central	0	yes	62.833	0.000	EPSD;PhosphoSitePlus	COSMIC	43.065	Loss
TK_PDGFR_PDGFRB_Y	P09619	PDGFRB	P09619	PDGFRB	Y579	P584S	584	Missense	distal	5	no	65.421	60.448	EPSD;PhosphoSitePlus	COSMIC	43.065	Down-regulation
TK_PDGFR_PDGFRB_Y	P09619	PDGFRB	P09619	PDGFRB	Y579	S574F	574	Missense	distal	-5	no	65.421	67.877	EPSD;PhosphoSitePlus	COSMIC	43.065	Up-regulation
TK_PDGFR_PDGFRB_Y	P09619	PDGFRB	P09619	PDGFRB	Y579	D583E	583	Missense	distal	4	no	65.421	65.566	EPSD;PhosphoSitePlus	COSMIC	43.065	Up-regulation
TK_PDGFR_PDGFRB_Y	P09619	PDGFRB	P09619	PDGFRB	Y581	P584S	584	Missense	distal	3	no	62.169	62.694	EPSD;PhosphoSitePlus	COSMIC	43.065	Up-regulation
TK_PDGFR_PDGFRB_Y	P09619	PDGFRB	P09619	PDGFRB	Y581	S574F	574	Missense	distal	-7	no	62.169	57.067	EPSD;PhosphoSitePlus	COSMIC	43.065	Down-regulation
TK_PDGFR_PDGFRB_Y	P09619	PDGFRB	P09619	PDGFRB	Y581	D583E	583	Missense	proximal	2	no	62.169	52.760	EPSD;PhosphoSitePlus	COSMIC	43.065	Down-regulation
TK_PDGFR_PDGFRB_Y	P09619	PDGFRB	P09619	PDGFRB	Y589	P584S	584	Missense	distal	-5	no	60.161	59.492	EPSD	COSMIC	43.065	Down-regulation
TK_PDGFR_PDGFRB_Y	P09619	PDGFRB	P09619	PDGFRB	Y589	Y589H	589	Missense	central	0	yes	60.161	0.000	EPSD	COSMIC	43.065	Loss
TK_PDGFR_PDGFRB_Y	P09619	PDGFRB	P09619	PDGFRB	Y589	P596R	596	Missense	distal	7	no	60.161	58.782	EPSD	COSMIC	43.065	Down-regulation
TK_PDGFR_PDGFRB_Y	P09619	PDGFRB	P09619	PDGFRB	Y589	S591F	591	Missense	proximal	2	no	60.161	40.577	EPSD	COSMIC	43.065	Loss
TK_PDGFR_PDGFRB_Y	P09619	PDGFRB	P09619	PDGFRB	Y589	D583E	583	Missense	distal	-6	no	60.161	57.263	EPSD	COSMIC	43.065	Down-regulation
TK_PDGFR_PDGFRB_Y	P09619	PDGFRB	P09619	PDGFRB	Y589	E594K	594	Missense	distal	5	no	60.161	62.288	EPSD	COSMIC	43.065	Up-regulation
TK_PDGFR_PDGFRB_Y	P09619	PDGFRB	P09619	PDGFRB	Y589	P596L	596	Missense	distal	7	no	60.161	58.020	EPSD	COSMIC	43.065	Down-regulation
TK_PDGFR_PDGFRB_Y	P09619	PDGFRB	P09619	PDGFRB	Y686	G687K	687	Missense	proximal	1	no	43.099	38.607	EPSD	COSMIC	43.065	Loss
TK_PDGFR_PDGFRB_Y	P09619	PDGFRB	P09619	PDGFRB	Y716	P710L	710	Missense	distal	-6	no	64.419	72.220	EPSD	COSMIC	43.065	Up-regulation
TK_PDGFR_PDGFRB_Y	P09619	PDGFRB	P09619	PDGFRB	Y716	A713V	713	Missense	distal	-3	no	64.419	63.415	EPSD	COSMIC	43.065	Down-regulation
TK_PDGFR_PDGFRB_Y	P09619	PDGFRB	P09619	PDGFRB	Y716	P711S	711	Missense	distal	-5	no	64.419	63.750	EPSD	COSMIC	43.065	Down-regulation
TK_PDGFR_PDGFRB_Y	P09619	PDGFRB	P09619	PDGFRB	Y716	R709H	709	Missense	distal	-7	no	64.419	64.077	EPSD	COSMIC	43.065	Down-regulation
TK_PDGFR_PDGFRB_Y	P09619	PDGFRB	P09619	PDGFRB	Y716	A713T	713	Missense	distal	-3	no	64.419	63.839	EPSD	COSMIC;GDSC;CCLE	43.065	Down-regulation
TK_PDGFR_PDGFRB_Y	P09619	PDGFRB	P09619	PDGFRB	Y740	T733I	733	Missense	distal	-7	no	66.534	66.532	EPSD;PhosphoSitePlus	COSMIC	43.065	Down-regulation
TK_PDGFR_PDGFRB_Y	P09619	PDGFRB	P09619	PDGFRB	Y740	G734E	734	Missense	distal	-6	no	66.534	66.859	EPSD;PhosphoSitePlus	COSMIC	43.065	Up-regulation
TK_PDGFR_PDGFRB_Y	P09619	PDGFRB	P09619	PDGFRB	Y740	D742N	742	Missense	proximal	2	no	66.534	59.239	EPSD;PhosphoSitePlus	COSMIC	43.065	Down-regulation
TK_PDGFR_PDGFRB_Y	P09619	PDGFRB	P09619	PDGFRB	Y751	D756N	756	Missense	distal	5	no	65.534	56.449	EPSD;PhosphoSitePlus	COSMIC	43.065	Down-regulation
TK_PDGFR_PDGFRB_Y	P09619	PDGFRB	P09619	PDGFRB	Y751	M757I	757	Missense	distal	6	no	65.534	63.668	EPSD;PhosphoSitePlus	COSMIC	43.065	Down-regulation
TK_PDGFR_PDGFRB_Y	P09619	PDGFRB	P09619	PDGFRB	Y751	P753T	753	Missense	proximal	2	no	65.534	62.766	EPSD;PhosphoSitePlus	COSMIC;GDSC;CCLE	43.065	Down-regulation
TK_PDGFR_PDGFRB_Y	P09619	PDGFRB	P09619	PDGFRB	Y763	D756N	756	Missense	distal	-7	no	65.240	66.863	EPSD;PhosphoSitePlus	COSMIC	43.065	Up-regulation
TK_PDGFR_PDGFRB_Y	P09619	PDGFRB	P09619	PDGFRB	Y763	Y763C	763	Missense	central	0	yes	65.240	0.000	EPSD;PhosphoSitePlus	COSMIC	43.065	Loss
TK_PDGFR_PDGFRB_Y	P09619	PDGFRB	P09619	PDGFRB	Y763	D760G	760	Missense	distal	-3	no	65.240	58.215	EPSD;PhosphoSitePlus	COSMIC	43.065	Down-regulation
TK_PDGFR_PDGFRB_Y	P09619	PDGFRB	P09619	PDGFRB	Y763	N770S	770	Missense	distal	7	no	65.240	65.408	EPSD;PhosphoSitePlus	COSMIC	43.065	Up-regulation
TK_PDGFR_PDGFRB_Y	P09619	PDGFRB	P09619	PDGFRB	Y763	M757I	757	Missense	distal	-6	no	65.240	64.503	EPSD;PhosphoSitePlus	COSMIC	43.065	Down-regulation
TK_PDGFR_PDGFRB_Y	P09619	PDGFRB	P09619	PDGFRB	Y763	E767D	767	Missense	distal	4	no	65.240	65.095	EPSD;PhosphoSitePlus	COSMIC	43.065	Down-regulation
TK_PDGFR_PDGFRB_Y	P09619	PDGFRB	P09619	PDGFRB	Y763	V761I	761	Missense	proximal	-2	no	65.240	57.825	EPSD;PhosphoSitePlus	COSMIC	43.065	Down-regulation
TK_PDGFR_PDGFRB_Y	P09619	PDGFRB	P09619	PDGFRB	Y771	N770S	770	Missense	proximal	-1	no	66.784	65.495	EPSD;PhosphoSitePlus	COSMIC	43.065	Down-regulation
TK_PDGFR_PDGFRB_Y	P09619	PDGFRB	P09619	PDGFRB	Y771	E767D	767	Missense	distal	-4	no	66.784	67.198	EPSD;PhosphoSitePlus	COSMIC	43.065	Up-regulation
TK_PDGFR_PDGFRB_Y	P09619	PDGFRB	P09619	PDGFRB	Y771	M772I	772	Missense	proximal	1	no	66.784	67.936	EPSD;PhosphoSitePlus	COSMIC;GDSC;CCLE	43.065	Up-regulation
TK_PDGFR_PDGFRB_Y	P09619	PDGFRB	P09619	PDGFRB	Y771	M772V	772	Missense	proximal	1	no	66.784	69.345	EPSD;PhosphoSitePlus	COSMIC	43.065	Up-regulation
TK_PDGFR_PDGFRB_Y	P09619	PDGFRB	P09619	PDGFRB	Y775	N770S	770	Missense	distal	-5	no	66.836	66.104	EPSD;PhosphoSitePlus	COSMIC	43.065	Down-regulation
TK_PDGFR_PDGFRB_Y	P09619	PDGFRB	P09619	PDGFRB	Y775	P780S	780	Missense	distal	5	no	66.836	61.863	EPSD;PhosphoSitePlus	COSMIC	43.065	Down-regulation
TK_PDGFR_PDGFRB_Y	P09619	PDGFRB	P09619	PDGFRB	Y775	P780F	780	Missense	distal	5	no	66.836	47.926	EPSD;PhosphoSitePlus	COSMIC	43.065	Down-regulation
TK_PDGFR_PDGFRB_Y	P09619	PDGFRB	P09619	PDGFRB	Y775	M772I	772	Missense	distal	-3	no	66.836	68.071	EPSD;PhosphoSitePlus	COSMIC;GDSC;CCLE	43.065	Up-regulation
TK_PDGFR_PDGFRB_Y	P09619	PDGFRB	P09619	PDGFRB	Y775	P780L	780	Missense	distal	5	no	66.836	40.117	EPSD;PhosphoSitePlus	COSMIC	43.065	Loss
TK_PDGFR_PDGFRB_Y	P09619	PDGFRB	P09619	PDGFRB	Y775	M772V	772	Missense	distal	-3	no	66.836	65.900	EPSD;PhosphoSitePlus	COSMIC	43.065	Down-regulation
TK_PDGFR_PDGFRB_Y	P09619	PDGFRB	P09619	PDGFRB	Y778	P780S	780	Missense	proximal	2	no	65.044	66.380	EPSD;PhosphoSitePlus	COSMIC	43.065	Up-regulation
TK_PDGFR_PDGFRB_Y	P09619	PDGFRB	P09619	PDGFRB	Y778	P780F	780	Missense	proximal	2	no	65.044	46.797	EPSD;PhosphoSitePlus	COSMIC	43.065	Down-regulation
TK_PDGFR_PDGFRB_Y	P09619	PDGFRB	P09619	PDGFRB	Y778	M772I	772	Missense	distal	-6	no	65.044	64.307	EPSD;PhosphoSitePlus	COSMIC;GDSC;CCLE	43.065	Down-regulation
TK_PDGFR_PDGFRB_Y	P09619	PDGFRB	P09619	PDGFRB	Y778	R785K	785	Missense	distal	7	no	65.044	67.402	EPSD;PhosphoSitePlus	COSMIC	43.065	Up-regulation
TK_PDGFR_PDGFRB_Y	P09619	PDGFRB	P09619	PDGFRB	Y778	P780L	780	Missense	proximal	2	no	65.044	56.341	EPSD;PhosphoSitePlus	COSMIC	43.065	Down-regulation
TK_PDGFR_PDGFRB_Y	P09619	PDGFRB	P09619	PDGFRB	Y778	M772V	772	Missense	distal	-6	no	65.044	59.605	EPSD;PhosphoSitePlus	COSMIC	43.065	Down-regulation
TK_PDGFR_PDGFRB_Y	P09619	PDGFRB	P09619	PDGFRB	Y857	D850V	850	Missense	distal	-7	no	68.992	71.657	EPSD;PhosphoSitePlus	COSMIC	43.065	Up-regulation
TK_PDGFR_PDGFRB_Y	P09619	PDGFRB	P09619	PDGFRB	Y857	S859A	859	Missense	proximal	2	no	68.992	66.540	EPSD;PhosphoSitePlus	COSMIC	43.065	Down-regulation
TK_PDGFR_PDGFRB_Y	P09619	PDGFRB	P09619	PDGFRB	Y857	R853P	853	Missense	distal	-4	no	68.992	71.246	EPSD;PhosphoSitePlus	COSMIC	43.065	Up-regulation
TK_PDGFR_PDGFRB_Y	P09619	PDGFRB	P09619	PDGFRB	Y857	S855W	855	Missense	proximal	-2	no	68.992	60.952	EPSD;PhosphoSitePlus	COSMIC	43.065	Down-regulation
TK_PDGFR_PDGFRB_Y	P09619	PDGFRB	P09619	PDGFRB	Y1009	S1006F	1006	Missense	distal	-3	no	67.172	56.142	EPSD;PhosphoSitePlus	COSMIC	43.065	Down-regulation
TK_PDGFR_PDGFRB_Y	P09619	PDGFRB	P09619	PDGFRB	Y1009	L1002R	1002	Missense	distal	-7	no	67.172	69.474	EPSD;PhosphoSitePlus	COSMIC	43.065	Up-regulation
TK_PDGFR_PDGFRB_Y	P09619	PDGFRB	P09619	PDGFRB	Y1009	A1011D	1011	Missense	proximal	2	no	67.172	76.385	EPSD;PhosphoSitePlus	COSMIC	43.065	Up-regulation
TK_PDGFR_PDGFRB_Y	P09619	PDGFRB	P09619	PDGFRB	Y1009	Y1009S	1009	Missense	central	0	yes	67.172	0.000	EPSD;PhosphoSitePlus	COSMIC	43.065	Loss
TK_PDGFR_PDGFRB_Y	P09619	PDGFRB	P09619	PDGFRB	Y1021	D1027N	1027	Missense	distal	6	no	59.451	60.745	PhosphoSitePlus;EPSD	COSMIC	43.065	Up-regulation
TK_PDGFR_PDGFRB_Y	P09619	PDGFRB	P09619	PDGFRB	Y1021	D1018Y	1018	Missense	distal	-3	no	59.451	50.887	PhosphoSitePlus;EPSD	COSMIC	43.065	Down-regulation
TK_PDGFR_PDGFRB_Y	P09619	PDGFRB	P09619	PDGFRB	Y1021	G1017D	1017	Missense	distal	-4	no	59.451	62.641	PhosphoSitePlus;EPSD	COSMIC	43.065	Up-regulation
TK_PDGFR_PDGFRB_Y	P16234	PDGFRA	P09619	PDGFRB	Y555	V561D	561	Missense	distal	6	no	48.071	46.476	EPSD	COSMIC	43.065	Down-regulation
TK_PDGFR_PDGFRB_Y	P16234	PDGFRA	P09619	PDGFRB	Y555	P553A	553	Missense	proximal	-2	no	48.071	49.468	EPSD	COSMIC	43.065	Up-regulation
TK_PDGFR_PDGFRB_Y	P16234	PDGFRA	P09619	PDGFRB	Y555	R560K	560	Missense	distal	5	no	48.071	61.311	EPSD	COSMIC	43.065	Up-regulation
TK_PDGFR_PDGFRB_Y	P16234	PDGFRA	P09619	PDGFRB	Y555	Y555C	555	Missense	central	0	yes	48.071	0.000	EPSD	COSMIC	43.065	Loss
TK_PDGFR_PDGFRB_Y	P16234	PDGFRA	P09619	PDGFRB	Y555	W559L	559	Missense	distal	4	no	48.071	47.982	EPSD	COSMIC	43.065	Down-regulation
TK_PDGFR_PDGFRB_Y	P16234	PDGFRA	P09619	PDGFRB	Y555	R560D	560	Missense	distal	5	no	48.071	63.146	EPSD	COSMIC	43.065	Up-regulation
TK_PDGFR_PDGFRB_Y	P16234	PDGFRA	P09619	PDGFRB	Y555	P553R	553	Missense	proximal	-2	no	48.071	43.612	EPSD	COSMIC	43.065	Down-regulation
TK_PDGFR_PDGFRB_Y	P16234	PDGFRA	P09619	PDGFRB	Y555	V561A	561	Missense	distal	6	no	48.071	47.069	EPSD	COSMIC	43.065	Down-regulation
TK_PDGFR_PDGFRB_Y	P16234	PDGFRA	P09619	PDGFRB	Y555	I562M	562	Missense	distal	7	no	48.071	46.509	EPSD	COSMIC	43.065	Down-regulation
TK_PDGFR_PDGFRB_Y	P16234	PDGFRA	P09619	PDGFRB	Y555	Q551K	551	Missense	distal	-4	no	48.071	48.629	EPSD	COSMIC	43.065	Up-regulation
TK_PDGFR_PDGFRB_Y	P16234	PDGFRA	P09619	PDGFRB	Y555	W559C	559	Missense	distal	4	no	48.071	48.064	EPSD	COSMIC	43.065	Down-regulation
TK_PDGFR_PDGFRB_Y	P16234	PDGFRA	P09619	PDGFRB	Y572	P577R	577	Missense	distal	5	no	50.468	36.675	EPSD	COSMIC	43.065	Loss
TK_PDGFR_PDGFRB_Y	P16234	PDGFRA	P09619	PDGFRB	Y572	P567T	567	Missense	distal	-5	no	50.468	50.932	EPSD	COSMIC	43.065	Up-regulation
TK_PDGFR_PDGFRB_Y	P16234	PDGFRA	P09619	PDGFRB	Y572	H570R	570	Missense	proximal	-2	no	50.468	48.323	EPSD	COSMIC	43.065	Down-regulation
TK_PDGFR_PDGFRB_Y	P16234	PDGFRA	P09619	PDGFRB	Y572	P577S	577	Missense	distal	5	no	50.468	45.495	EPSD	COSMIC	43.065	Down-regulation
TK_PDGFR_PDGFRB_Y	P16234	PDGFRA	P09619	PDGFRB	Y572	P567S	567	Missense	distal	-5	no	50.468	49.799	EPSD	COSMIC	43.065	Down-regulation
TK_PDGFR_PDGFRB_Y	P16234	PDGFRA	P09619	PDGFRB	Y572	D568Y	568	Missense	distal	-4	no	50.468	48.438	EPSD	COSMIC	43.065	Down-regulation
TK_PDGFR_PDGFRB_Y	P16234	PDGFRA	P09619	PDGFRB	Y572	G569V	569	Missense	distal	-3	no	50.468	48.156	EPSD	COSMIC	43.065	Down-regulation
TK_PDGFR_PDGFRB_Y	P16234	PDGFRA	P09619	PDGFRB	Y572	E571L	571	Missense	proximal	-1	no	50.468	41.195	EPSD	COSMIC	43.065	Loss
TK_PDGFR_PDGFRB_Y	P16234	PDGFRA	P09619	PDGFRB	Y572	I565V	565	Missense	distal	-7	no	50.468	53.677	EPSD	COSMIC	43.065	Up-regulation
TK_PDGFR_PDGFRB_Y	P16234	PDGFRA	P09619	PDGFRB	Y574	P581S	581	Missense	distal	7	no	51.135	52.084	EPSD	COSMIC	43.065	Up-regulation
TK_PDGFR_PDGFRB_Y	P16234	PDGFRA	P09619	PDGFRB	Y574	P577R	577	Missense	distal	3	no	51.135	51.062	EPSD	COSMIC	43.065	Down-regulation
TK_PDGFR_PDGFRB_Y	P16234	PDGFRA	P09619	PDGFRB	Y574	P567T	567	Missense	distal	-7	no	51.135	48.271	EPSD	COSMIC	43.065	Down-regulation
TK_PDGFR_PDGFRB_Y	P16234	PDGFRA	P09619	PDGFRB	Y574	H570R	570	Missense	distal	-4	no	51.135	50.932	EPSD	COSMIC	43.065	Down-regulation
TK_PDGFR_PDGFRB_Y	P16234	PDGFRA	P09619	PDGFRB	Y574	L580M	580	Missense	distal	6	no	51.135	53.991	EPSD	COSMIC	43.065	Up-regulation
TK_PDGFR_PDGFRB_Y	P16234	PDGFRA	P09619	PDGFRB	Y574	P577S	577	Missense	distal	3	no	51.135	51.660	EPSD	COSMIC	43.065	Up-regulation
TK_PDGFR_PDGFRB_Y	P16234	PDGFRA	P09619	PDGFRB	Y574	P567S	567	Missense	distal	-7	no	51.135	50.976	EPSD	COSMIC	43.065	Down-regulation
TK_PDGFR_PDGFRB_Y	P16234	PDGFRA	P09619	PDGFRB	Y574	D568Y	568	Missense	distal	-6	no	51.135	43.767	EPSD	COSMIC	43.065	Down-regulation
TK_PDGFR_PDGFRB_Y	P16234	PDGFRA	P09619	PDGFRB	Y574	G569V	569	Missense	distal	-5	no	51.135	49.738	EPSD	COSMIC	43.065	Down-regulation
TK_PDGFR_PDGFRB_Y	P16234	PDGFRA	P09619	PDGFRB	Y574	E571L	571	Missense	distal	-3	no	51.135	44.633	EPSD	COSMIC	43.065	Down-regulation
TK_PDGFR_PDGFRB_Y	P16234	PDGFRA	P09619	PDGFRB	Y582	P589T	589	Missense	distal	7	no	57.225	55.933	EPSD	COSMIC	43.065	Down-regulation
TK_PDGFR_PDGFRB_Y	P16234	PDGFRA	P09619	PDGFRB	Y582	P581S	581	Missense	proximal	-1	no	57.225	56.737	EPSD	COSMIC	43.065	Down-regulation
TK_PDGFR_PDGFRB_Y	P16234	PDGFRA	P09619	PDGFRB	Y582	P577R	577	Missense	distal	-5	no	57.225	58.267	EPSD	COSMIC	43.065	Up-regulation
TK_PDGFR_PDGFRB_Y	P16234	PDGFRA	P09619	PDGFRB	Y582	E587K	587	Missense	distal	5	no	57.225	59.352	EPSD	COSMIC	43.065	Up-regulation
TK_PDGFR_PDGFRB_Y	P16234	PDGFRA	P09619	PDGFRB	Y582	P589S	589	Missense	distal	7	no	57.225	58.173	EPSD	COSMIC	43.065	Up-regulation
TK_PDGFR_PDGFRB_Y	P16234	PDGFRA	P09619	PDGFRB	Y582	P589L	589	Missense	distal	7	no	57.225	55.084	EPSD	COSMIC	43.065	Down-regulation
TK_PDGFR_PDGFRB_Y	P16234	PDGFRA	P09619	PDGFRB	Y582	D583Y	583	Missense	proximal	1	no	57.225	58.082	EPSD	COSMIC	43.065	Up-regulation
TK_PDGFR_PDGFRB_Y	P16234	PDGFRA	P09619	PDGFRB	Y582	L580M	580	Missense	proximal	-2	no	57.225	62.946	EPSD	COSMIC	43.065	Up-regulation
TK_PDGFR_PDGFRB_Y	P16234	PDGFRA	P09619	PDGFRB	Y582	P577S	577	Missense	distal	-5	no	57.225	56.556	EPSD	COSMIC	43.065	Down-regulation
TK_PDGFR_PDGFRB_Y	P16234	PDGFRA	P09619	PDGFRB	Y582	D583G	583	Missense	proximal	1	no	57.225	57.953	EPSD	COSMIC	43.065	Up-regulation
TK_PDGFR_PDGFRB_Y	P16234	PDGFRA	P09619	PDGFRB	Y731	F725L	725	Missense	distal	-6	no	55.105	56.770	EPSD	COSMIC	43.065	Up-regulation
TK_PDGFR_PDGFRB_Y	P16234	PDGFRA	P09619	PDGFRB	Y731	M732V	732	Missense	proximal	1	no	55.105	57.667	EPSD	COSMIC	43.065	Up-regulation
TK_PDGFR_PDGFRB_Y	P16234	PDGFRA	P09619	PDGFRB	Y731	Q736H	736	Missense	distal	5	no	55.105	47.761	EPSD	COSMIC;CCLE	43.065	Down-regulation
TK_PDGFR_PDGFRB_Y	P16234	PDGFRA	P09619	PDGFRB	Y731	M732I	732	Missense	proximal	1	no	55.105	56.258	EPSD	COSMIC	43.065	Up-regulation
TK_PDGFR_PDGFRB_Y	P16234	PDGFRA	P09619	PDGFRB	Y731	G729S	729	Missense	proximal	-2	no	55.105	56.442	EPSD	COSMIC	43.065	Up-regulation
TK_PDGFR_PDGFRB_Y	P16234	PDGFRA	P09619	PDGFRB	Y731	S724Y	724	Missense	distal	-7	no	55.105	54.736	EPSD	COSMIC	43.065	Down-regulation
TK_PDGFR_PDGFRB_Y	P16234	PDGFRA	P09619	PDGFRB	Y754	R748G	748	Missense	distal	-6	no	64.177	59.015	PhosphoSitePlus	COSMIC	43.065	Down-regulation
TK_PDGFR_PDGFRB_Y	P16234	PDGFRA	P09619	PDGFRB	Y754	E750D	750	Missense	distal	-4	no	64.177	64.592	PhosphoSitePlus	COSMIC	43.065	Up-regulation
TK_PDGFR_PDGFRB_Y	P16234	PDGFRA	P09619	PDGFRB	Y754	Q758R	758	Missense	distal	4	no	64.177	64.302	PhosphoSitePlus	COSMIC	43.065	Up-regulation
TK_PDGFR_PDGFRB_Y	P16234	PDGFRA	P09619	PDGFRB	Y754	E747Q	747	Missense	distal	-7	no	64.177	63.086	PhosphoSitePlus	COSMIC	43.065	Down-regulation
TK_PDGFR_PDGFRB_Y	P16234	PDGFRA	P09619	PDGFRB	Y754	E747K	747	Missense	distal	-7	no	64.177	64.317	PhosphoSitePlus	COSMIC	43.065	Up-regulation
TK_PDGFR_PDGFRB_Y	P16234	PDGFRA	P09619	PDGFRB	Y754	E747G	747	Missense	distal	-7	no	64.177	64.249	PhosphoSitePlus	COSMIC	43.065	Up-regulation
TK_PDGFR_PDGFRB_Y	P16234	PDGFRA	P09619	PDGFRB	Y849	D842V	842	Missense	distal	-7	no	72.976	75.641	EPSD	COSMIC	43.065	Up-regulation
TK_PDGFR_PDGFRB_Y	P16234	PDGFRA	P09619	PDGFRB	Y849	Y849D	849	Missense	central	0	yes	72.976	0.000	EPSD	COSMIC	43.065	Loss
TK_PDGFR_PDGFRB_Y	P16234	PDGFRA	P09619	PDGFRB	Y849	D846Y	846	Missense	distal	-3	no	72.976	64.412	EPSD	COSMIC	43.065	Down-regulation
TK_PDGFR_PDGFRB_Y	P16234	PDGFRA	P09619	PDGFRB	Y849	H845Y	845	Missense	distal	-4	no	72.976	73.269	EPSD	COSMIC	43.065	Up-regulation
TK_PDGFR_PDGFRB_Y	P16234	PDGFRA	P09619	PDGFRB	Y849	D842I	842	Missense	distal	-7	no	72.976	72.432	EPSD	COSMIC	43.065	Down-regulation
TK_PDGFR_PDGFRB_Y	P16234	PDGFRA	P09619	PDGFRB	Y849	Y849H	849	Missense	central	0	yes	72.976	0.000	EPSD	COSMIC	43.065	Loss
TK_PDGFR_PDGFRB_Y	P16234	PDGFRA	P09619	PDGFRB	Y849	Y849C	849	Missense	central	0	yes	72.976	0.000	EPSD	COSMIC	43.065	Loss
TK_PDGFR_PDGFRB_Y	P16234	PDGFRA	P09619	PDGFRB	Y849	D846E	846	Missense	distal	-3	no	72.976	65.408	EPSD	COSMIC	43.065	Down-regulation
TK_PDGFR_PDGFRB_Y	P16234	PDGFRA	P09619	PDGFRB	Y849	D842E	842	Missense	distal	-7	no	72.976	74.569	EPSD	COSMIC	43.065	Up-regulation
TK_PDGFR_PDGFRB_Y	P16234	PDGFRA	P09619	PDGFRB	Y849	S851W	851	Missense	proximal	2	no	72.976	61.747	EPSD	COSMIC	43.065	Down-regulation
TK_PDGFR_PDGFRB_Y	P16234	PDGFRA	P09619	PDGFRB	Y849	D842H	842	Missense	distal	-7	no	72.976	71.349	EPSD	COSMIC	43.065	Down-regulation
TK_PDGFR_PDGFRB_Y	P16234	PDGFRA	P09619	PDGFRB	Y849	D846V	846	Missense	distal	-3	no	72.976	63.638	EPSD	COSMIC	43.065	Down-regulation
TK_PDGFR_PDGFRB_Y	P16234	PDGFRA	P09619	PDGFRB	Y849	D846A	846	Missense	distal	-3	no	72.976	64.642	EPSD	COSMIC	43.065	Down-regulation
TK_PDGFR_PDGFRB_Y	P16234	PDGFRA	P09619	PDGFRB	Y849	D846G	846	Missense	distal	-3	no	72.976	65.951	EPSD	COSMIC	43.065	Down-regulation
TK_PDGFR_PDGFRB_Y	P16234	PDGFRA	P09619	PDGFRB	Y849	S851P	851	Missense	proximal	2	no	72.976	71.640	EPSD	COSMIC	43.065	Down-regulation
TK_PDGFR_PDGFRB_Y	P16234	PDGFRA	P09619	PDGFRB	Y849	D842A	842	Missense	distal	-7	no	72.976	76.381	EPSD	COSMIC	43.065	Up-regulation
TK_PDGFR_PDGFRB_Y	P16234	PDGFRA	P09619	PDGFRB	Y849	M844V	844	Missense	distal	-5	no	72.976	71.883	EPSD	COSMIC	43.065	Down-regulation
TK_PDGFR_PDGFRB_Y	P16234	PDGFRA	P09619	PDGFRB	Y849	H845D	845	Missense	distal	-4	no	72.976	75.299	EPSD	COSMIC	43.065	Up-regulation
TK_PDGFR_PDGFRB_Y	P16234	PDGFRA	P09619	PDGFRB	Y849	D842F	842	Missense	distal	-7	no	72.976	70.037	EPSD	COSMIC	43.065	Down-regulation
TK_PDGFR_PDGFRB_Y	P16234	PDGFRA	P09619	PDGFRB	Y849	I843V	843	Missense	distal	-6	no	72.976	68.274	EPSD	COSMIC	43.065	Down-regulation
TK_PDGFR_PDGFRB_Y	P16234	PDGFRA	P09619	PDGFRB	Y993	I989T	989	Missense	distal	-4	no	41.445	43.491	EPSD	COSMIC	43.065	Gain
TK_PDGFR_PDGFRB_Y	P16234	PDGFRA	P09619	PDGFRB	Y1018	G1017V	1017	Missense	proximal	-1	no	37.965	43.549	EPSD	COSMIC;GDSC;CCLE	43.065	Gain
TK_PDGFR_PDGFRB_Y	P16234	PDGFRA	P09619	PDGFRB	Y1018	G1017D	1017	Missense	proximal	-1	no	37.965	46.048	EPSD	COSMIC	43.065	Gain
TK_PDGFR_PDGFRB_Y	Q05397	PTK2	P09619	PDGFRB	Y5	A3T	3	Missense	proximal	-2	no	52.065	50.226	PhosphoSitePlus;EPSD	COSMIC	43.065	Down-regulation
TK_PDGFR_PDGFRB_Y	Q05397	PTK2	P09619	PDGFRB	Y5	H12D	12	Missense	distal	7	no	52.065	55.134	PhosphoSitePlus;EPSD	COSMIC	43.065	Up-regulation
TK_PDGFR_PDGFRB_Y	Q05397	PTK2	P09619	PDGFRB	Y5	A4T	4	Missense	proximal	-1	no	52.065	50.995	PhosphoSitePlus;EPSD	COSMIC	43.065	Down-regulation
TK_PDGFR_PDGFRB_Y	Q05397	PTK2	P09619	PDGFRB	Y397	S390A	390	Missense	distal	-7	no	42.383	43.625	EPSD	COSMIC	43.065	Gain
TK_PDGFR_PDGFRB_Y	Q05397	PTK2	P09619	PDGFRB	Y397	V391A	391	Missense	distal	-6	no	42.383	47.074	EPSD	COSMIC	43.065	Gain
TK_PDGFR_PDGFRB_Y	Q05397	PTK2	P09619	PDGFRB	Y576	R569L	569	Missense	distal	-7	no	63.371	61.069	EPSD	COSMIC	43.065	Down-regulation
TK_PDGFR_PDGFRB_Y	Q05397	PTK2	P09619	PDGFRB	Y576	A579V	579	Missense	distal	3	no	63.371	63.507	EPSD	COSMIC	43.065	Up-regulation
TK_PDGFR_PDGFRB_Y	Q05397	PTK2	P09619	PDGFRB	Y720	S722I	722	Missense	proximal	2	no	44.465	38.167	EPSD	COSMIC	43.065	Loss
TK_PDGFR_PDGFRB_Y	Q05397	PTK2	P09619	PDGFRB	Y925	D918G	918	Missense	distal	-7	no	42.449	44.114	EPSD	COSMIC	43.065	Gain
TK_PDGFR_PDGFRB_Y	Q05397	PTK2	P09619	PDGFRB	Y925	E926K	926	Missense	proximal	1	no	42.449	43.318	EPSD	COSMIC	43.065	Gain
TK_PDGFR_PDGFRB_Y	P42684	ABL2	P09619	PDGFRB	Y80	R78C	78	Missense	proximal	-2	no	43.485	40.739	EPSD	COSMIC	43.065	Loss
TK_PDGFR_PDGFRB_Y	P42684	ABL2	P09619	PDGFRB	Y80	E85K	85	Missense	distal	5	no	43.485	45.611	EPSD	COSMIC	43.065	Up-regulation
TK_PDGFR_PDGFRB_Y	P42684	ABL2	P09619	PDGFRB	Y139	R135Q	135	Missense	distal	-4	no	63.428	64.955	EPSD;PhosphoSitePlus	COSMIC;CCLE	43.065	Up-regulation
TK_PDGFR_PDGFRB_Y	P42684	ABL2	P09619	PDGFRB	Y139	G143A	143	Missense	distal	4	no	63.428	62.917	EPSD;PhosphoSitePlus	COSMIC	43.065	Down-regulation
TK_PDGFR_PDGFRB_Y	P42684	ABL2	P09619	PDGFRB	Y139	G143D	143	Missense	distal	4	no	63.428	63.214	EPSD;PhosphoSitePlus	COSMIC	43.065	Down-regulation
TK_PDGFR_PDGFRB_Y	P42684	ABL2	P09619	PDGFRB	Y139	Q141K	141	Missense	proximal	2	no	63.428	68.694	EPSD;PhosphoSitePlus	COSMIC	43.065	Up-regulation
TK_PDGFR_PDGFRB_Y	P42684	ABL2	P09619	PDGFRB	Y139	L137F	137	Missense	proximal	-2	no	63.428	60.657	EPSD;PhosphoSitePlus	COSMIC	43.065	Down-regulation
TK_PDGFR_PDGFRB_Y	P42684	ABL2	P09619	PDGFRB	Y139	S146N	146	Missense	distal	7	no	63.428	63.260	EPSD;PhosphoSitePlus	COSMIC	43.065	Down-regulation
TK_PDGFR_PDGFRB_Y	P42684	ABL2	P09619	PDGFRB	Y161	P164S	164	Missense	distal	3	no	69.382	69.907	EPSD;PhosphoSitePlus	COSMIC	43.065	Up-regulation
TK_PDGFR_PDGFRB_Y	P42684	ABL2	P09619	PDGFRB	Y161	G155V	155	Missense	distal	-6	no	69.382	63.792	EPSD;PhosphoSitePlus	COSMIC	43.065	Down-regulation
TK_PDGFR_PDGFRB_Y	P42684	ABL2	P09619	PDGFRB	Y272	S275P	275	Missense	distal	3	no	74.471	73.946	PhosphoSitePlus;EPSD	COSMIC	43.065	Down-regulation
TK_PDGFR_PDGFRB_Y	P42684	ABL2	P09619	PDGFRB	Y272	P276H	276	Missense	distal	4	no	74.471	74.254	PhosphoSitePlus;EPSD	COSMIC	43.065	Down-regulation
TK_PDGFR_PDGFRB_Y	P42684	ABL2	P09619	PDGFRB	Y272	H278Y	278	Missense	distal	6	no	74.471	74.531	PhosphoSitePlus;EPSD	COSMIC	43.065	Up-regulation
TK_PDGFR_PDGFRB_Y	P42684	ABL2	P09619	PDGFRB	Y272	D279N	279	Missense	distal	7	no	74.471	73.278	PhosphoSitePlus;EPSD	COSMIC	43.065	Down-regulation
TK_PDGFR_PDGFRB_Y	P42684	ABL2	P09619	PDGFRB	Y439	H442Y	442	Missense	distal	3	no	62.128	62.430	EPSD	COSMIC	43.065	Up-regulation
TK_PDGFR_PDGFRB_Y	P42684	ABL2	P09619	PDGFRB	Y568	I574M	574	Missense	distal	6	no	41.667	43.533	EPSD	COSMIC	43.065	Gain
TK_PDGFR_PDGFRB_Y	P42684	ABL2	P09619	PDGFRB	Y568	S563L	563	Missense	distal	-5	no	41.667	44.324	EPSD	COSMIC	43.065	Gain
TK_PDGFR_PDGFRB_Y	P19174	PLCG1	P09619	PDGFRB	Y472	E473K	473	Missense	proximal	1	no	49.225	50.094	EPSD	COSMIC	43.065	Up-regulation
TK_PDGFR_PDGFRB_Y	P19174	PLCG1	P09619	PDGFRB	Y518	S520Y	520	Missense	proximal	2	no	47.017	37.249	EPSD	COSMIC	43.065	Loss
TK_PDGFR_PDGFRB_Y	P19174	PLCG1	P09619	PDGFRB	Y518	S525I	525	Missense	distal	7	no	47.017	46.397	EPSD	COSMIC	43.065	Down-regulation
TK_PDGFR_PDGFRB_Y	P19174	PLCG1	P09619	PDGFRB	Y518	S520F	520	Missense	proximal	2	no	47.017	27.433	EPSD	COSMIC	43.065	Loss
TK_PDGFR_PDGFRB_Y	P19174	PLCG1	P09619	PDGFRB	Y518	S525T	525	Missense	distal	7	no	47.017	44.776	EPSD	COSMIC	43.065	Down-regulation
TK_PDGFR_PDGFRB_Y	P19174	PLCG1	P09619	PDGFRB	Y669	W668G	668	Missense	proximal	-1	no	39.835	44.457	EPSD	COSMIC	43.065	Gain
TK_PDGFR_PDGFRB_Y	P19174	PLCG1	P09619	PDGFRB	Y977	P984L	984	Missense	distal	7	no	51.813	49.672	EPSD	COSMIC	43.065	Down-regulation
TK_PDGFR_PDGFRB_Y	P19174	PLCG1	P09619	PDGFRB	Y977	R978Q	978	Missense	proximal	1	no	51.813	52.762	EPSD	COSMIC	43.065	Up-regulation
TK_PDGFR_PDGFRB_Y	P19174	PLCG1	P09619	PDGFRB	Y991	A995P	995	Missense	distal	4	no	43.594	44.102	EPSD	COSMIC;GDSC;CCLE	43.065	Up-regulation
TK_PDGFR_PDGFRB_Y	P19174	PLCG1	P09619	PDGFRB	Y991	G997S	997	Missense	distal	6	no	43.594	44.190	EPSD	COSMIC	43.065	Up-regulation
TK_PDGFR_PDGFRB_Y	P19174	PLCG1	P09619	PDGFRB	Y991	P984L	984	Missense	distal	-7	no	43.594	37.686	EPSD	COSMIC	43.065	Loss
TK_PDGFR_PDGFRB_Y	P19174	PLCG1	P09619	PDGFRB	Y1253	G1247A	1247	Missense	distal	-6	no	44.142	43.243	EPSD	COSMIC	43.065	Down-regulation
TK_PDGFR_PDGFRB_Y	P19174	PLCG1	P09619	PDGFRB	Y1253	P1256Q	1256	Missense	distal	3	no	44.142	44.432	EPSD	COSMIC	43.065	Up-regulation
TK_PDGFR_PDGFRB_Y	P19174	PLCG1	P09619	PDGFRB	Y1253	E1258K	1258	Missense	distal	5	no	44.142	46.269	EPSD	COSMIC	43.065	Up-regulation
TK_PDGFR_PDGFRB_Y	P19174	PLCG1	P09619	PDGFRB	Y1253	Q1254K	1254	Missense	proximal	1	no	44.142	42.320	EPSD	COSMIC	43.065	Loss
TK_PDGFR_PDGFRB_Y	P06241	FYN	P09619	PDGFRB	Y28	T35I	35	Missense	distal	7	no	53.550	55.171	PhosphoSitePlus	COSMIC	43.065	Up-regulation
TK_PDGFR_PDGFRB_Y	P06241	FYN	P09619	PDGFRB	Y28	N23D	23	Missense	distal	-5	no	53.550	53.387	PhosphoSitePlus	COSMIC	43.065	Down-regulation
TK_PDGFR_PDGFRB_Y	P06241	FYN	P09619	PDGFRB	Y28	P34A	34	Missense	distal	6	no	53.550	53.554	PhosphoSitePlus	COSMIC	43.065	Up-regulation
TK_PDGFR_PDGFRB_Y	P06241	FYN	P09619	PDGFRB	Y28	P34L	34	Missense	distal	6	no	53.550	50.755	PhosphoSitePlus	COSMIC	43.065	Down-regulation
TK_PDGFR_PDGFRB_Y	P06241	FYN	P09619	PDGFRB	Y28	R29C	29	Missense	proximal	1	no	53.550	52.653	PhosphoSitePlus	COSMIC	43.065	Down-regulation
TK_PDGFR_PDGFRB_Y	P06241	FYN	P09619	PDGFRB	Y420	R413Q	413	Missense	distal	-7	no	70.746	72.531	EPSD	COSMIC	43.065	Up-regulation
TK_PDGFR_PDGFRB_Y	Q07912	TNK2	P09619	PDGFRB	Y40	R34L	34	Missense	distal	-6	no	48.546	48.260	EPSD	COSMIC;CCLE	43.065	Down-regulation
TK_PDGFR_PDGFRB_Y	Q07912	TNK2	P09619	PDGFRB	Y40	R34C	34	Missense	distal	-6	no	48.546	46.236	EPSD	COSMIC	43.065	Down-regulation
TK_PDGFR_PDGFRB_Y	Q07912	TNK2	P09619	PDGFRB	Y284	H289N	289	Missense	distal	5	no	41.679	49.733	EPSD	COSMIC	43.065	Gain
TK_PDGFR_PDGFRB_Y	Q07912	TNK2	P09619	PDGFRB	Y284	P278H	278	Missense	distal	-6	no	41.679	44.553	EPSD	COSMIC	43.065	Gain
TK_PDGFR_PDGFRB_Y	Q07912	TNK2	P09619	PDGFRB	Y635	P632S	632	Missense	distal	-3	no	67.743	70.702	PhosphoSitePlus	COSMIC	43.065	Up-regulation
TK_PDGFR_PDGFRB_Y	Q07912	TNK2	P09619	PDGFRB	Y635	A634T	634	Missense	proximal	-1	no	67.743	66.673	PhosphoSitePlus	COSMIC	43.065	Down-regulation
TK_PDGFR_PDGFRB_Y	Q07912	TNK2	P09619	PDGFRB	Y827	T829N	829	Missense	proximal	2	no	46.506	50.076	EPSD	COSMIC	43.065	Up-regulation
TK_PDGFR_PDGFRB_Y	Q07912	TNK2	P09619	PDGFRB	Y827	P830L	830	Missense	distal	3	no	46.506	46.399	EPSD	COSMIC	43.065	Down-regulation
TK_PDGFR_PDGFRB_Y	P15941	MUC1	P09619	PDGFRB	Y1203	P1205L	1205	Missense	proximal	2	no	62.495	53.792	EPSD;PhosphoSitePlus	COSMIC	43.065	Down-regulation
TK_PDGFR_PDGFRB_Y	P15941	MUC1	P09619	PDGFRB	Y1203	P1205S	1205	Missense	proximal	2	no	62.495	63.831	EPSD;PhosphoSitePlus	COSMIC	43.065	Up-regulation
TK_PDGFR_PDGFRB_Y	P12931	SRC	P09619	PDGFRB	Y419	A421V	421	Missense	proximal	2	no	73.742	72.911	PhosphoSitePlus	COSMIC	43.065	Down-regulation
TK_PDGFR_PDGFRB_Y	P12931	SRC	P09619	PDGFRB	Y419	Y419H	419	Missense	central	0	yes	73.742	0.000	PhosphoSitePlus	COSMIC	43.065	Loss
TK_FGFR_FGFR4_Y	P22455	FGFR4	P22455	FGFR4	Y390	R391P	391	Missense	proximal	1	no	1.625	1.563	EPSD	COSMIC	1.608	Loss
TK_FGFR_FGFR4_Y	P22455	FGFR4	P22455	FGFR4	Y390	A387V	387	Missense	distal	-3	no	1.625	1.688	EPSD	COSMIC	1.608	Up-regulation
TK_FGFR_FGFR4_Y	P22455	FGFR4	P22455	FGFR4	Y390	R391Q	391	Missense	proximal	1	no	1.625	1.568	EPSD	COSMIC;GDSC	1.608	Loss
TK_FGFR_FGFR4_Y	P22455	FGFR4	P22455	FGFR4	Y390	H396R	396	Missense	distal	6	no	1.625	1.572	EPSD	COSMIC	1.608	Loss
TK_FGFR_FGFR4_Y	P22455	FGFR4	P22455	FGFR4	Y642	G636R	636	Missense	distal	-6	no	4.747	4.813	EPSD	COSMIC	1.608	Up-regulation
TK_FGFR_FGFR4_Y	P22455	FGFR4	P22455	FGFR4	Y642	R635S	635	Missense	distal	-7	no	4.747	4.295	EPSD	COSMIC	1.608	Down-regulation
TK_FGFR_FGFR4_Y	P22455	FGFR4	P22455	FGFR4	Y642	D641N	641	Missense	proximal	-1	no	4.747	4.513	EPSD	COSMIC	1.608	Down-regulation
TK_FGFR_FGFR4_Y	P22455	FGFR4	P22455	FGFR4	Y642	I640T	640	Missense	proximal	-2	no	4.747	4.752	EPSD	COSMIC	1.608	Up-regulation
TK_FGFR_FGFR4_Y	P22455	FGFR4	P22455	FGFR4	Y642	T646P	646	Missense	distal	4	no	4.747	4.751	EPSD	COSMIC	1.608	Up-regulation
TK_FGFR_FGFR4_Y	P22455	FGFR4	P22455	FGFR4	Y642	I640M	640	Missense	proximal	-2	no	4.747	4.734	EPSD	COSMIC	1.608	Down-regulation
TK_FGFR_FGFR4_Y	P22455	FGFR4	P22455	FGFR4	Y642	V637I	637	Missense	distal	-5	no	4.747	4.767	EPSD	COSMIC	1.608	Up-regulation
TK_FGFR_FGFR4_Y	P22455	FGFR4	P22455	FGFR4	Y642	G636C	636	Missense	distal	-6	no	4.747	4.488	EPSD	COSMIC	1.608	Down-regulation
TK_FGFR_FGFR4_Y	P22455	FGFR4	P22455	FGFR4	Y642	D641G	641	Missense	proximal	-1	no	4.747	4.503	EPSD	COSMIC	1.608	Down-regulation
TK_FGFR_FGFR4_Y	P22455	FGFR4	P22455	FGFR4	Y643	G636R	636	Missense	distal	-7	no	4.973	4.774	EPSD	COSMIC	1.608	Down-regulation
TK_FGFR_FGFR4_Y	P22455	FGFR4	P22455	FGFR4	Y643	D641N	641	Missense	proximal	-2	no	4.973	5.013	EPSD	COSMIC	1.608	Up-regulation
TK_FGFR_FGFR4_Y	P22455	FGFR4	P22455	FGFR4	Y643	I640T	640	Missense	distal	-3	no	4.973	4.954	EPSD	COSMIC	1.608	Down-regulation
TK_FGFR_FGFR4_Y	P22455	FGFR4	P22455	FGFR4	Y643	T646P	646	Missense	distal	3	no	4.973	4.946	EPSD	COSMIC	1.608	Down-regulation
TK_FGFR_FGFR4_Y	P22455	FGFR4	P22455	FGFR4	Y643	I640M	640	Missense	distal	-3	no	4.973	4.963	EPSD	COSMIC	1.608	Down-regulation
TK_FGFR_FGFR4_Y	P22455	FGFR4	P22455	FGFR4	Y643	R650H	650	Missense	distal	7	no	4.973	4.762	EPSD	COSMIC	1.608	Down-regulation
TK_FGFR_FGFR4_Y	P22455	FGFR4	P22455	FGFR4	Y643	V637I	637	Missense	distal	-6	no	4.973	4.904	EPSD	COSMIC	1.608	Down-regulation
TK_FGFR_FGFR4_Y	P22455	FGFR4	P22455	FGFR4	Y643	G636C	636	Missense	distal	-7	no	4.973	4.468	EPSD	COSMIC	1.608	Down-regulation
TK_FGFR_FGFR4_Y	P22455	FGFR4	P22455	FGFR4	Y643	D641G	641	Missense	proximal	-2	no	4.973	5.018	EPSD	COSMIC	1.608	Up-regulation
TK_FGFR_FGFR4_Y	P22455	FGFR4	P22455	FGFR4	Y754	R758C	758	Missense	distal	4	no	4.451	4.441	PhosphoSitePlus	COSMIC	1.608	Down-regulation
TK_FGFR_FGFR4_Y	P22455	FGFR4	P22455	FGFR4	Y754	A749V	749	Missense	distal	-5	no	4.451	4.416	PhosphoSitePlus	COSMIC	1.608	Down-regulation
TK_FGFR_FGFR4_Y	P22455	FGFR4	P22455	FGFR4	Y754	R758H	758	Missense	distal	4	no	4.451	4.445	PhosphoSitePlus	COSMIC	1.608	Down-regulation
TK_FGFR_FGFR4_Y	P22455	FGFR4	P22455	FGFR4	Y754	Y754C	754	Missense	central	0	yes	4.451	0.000	PhosphoSitePlus	COSMIC	1.608	Loss
CMGC_CDK_CDK7_CDK7_ST	P21127	CDK11B	P50613	CDK7	S38	D40N	40	Missense	proximal	2	no	14.733	13.831	EPSD	COSMIC	13.598	Down-regulation
CMGC_CDK_CDK7_CDK7_ST	P21127	CDK11B	P50613	CDK7	S38	S38Y	38	Missense	central	0	yes	14.733	0.000	EPSD	COSMIC	13.598	Loss
CMGC_CDK_CDK7_CDK7_ST	P21127	CDK11B	P50613	CDK7	S38	S38F	38	Missense	central	0	yes	14.733	0.000	EPSD	COSMIC	13.598	Loss
CMGC_CDK_CDK7_CDK7_ST	P21127	CDK11B	P50613	CDK7	T61	R57C	57	Missense	distal	-4	no	18.051	18.003	EPSD	COSMIC	13.598	Down-regulation
CMGC_CDK_CDK7_CDK7_ST	P21127	CDK11B	P50613	CDK7	S285	Q280R	280	Missense	distal	-5	no	14.769	14.847	EPSD	COSMIC	13.598	Up-regulation
CMGC_CDK_CDK7_CDK7_ST	P21127	CDK11B	P50613	CDK7	S398	E393D	393	Missense	distal	-5	no	17.481	15.242	EPSD	COSMIC	13.598	Down-regulation
CMGC_CDK_CDK7_CDK7_ST	P21127	CDK11B	P50613	CDK7	S398	A400V	400	Missense	proximal	2	no	17.481	18.581	EPSD	COSMIC	13.598	Up-regulation
CMGC_CDK_CDK7_CDK7_ST	P21127	CDK11B	P50613	CDK7	S398	D405N	405	Missense	distal	7	no	17.481	16.677	EPSD	COSMIC	13.598	Down-regulation
CMGC_CDK_CDK7_CDK7_ST	P21127	CDK11B	P50613	CDK7	S398	E403D	403	Missense	distal	5	no	17.481	17.651	EPSD	COSMIC	13.598	Up-regulation
CMGC_CDK_CDK7_CDK7_ST	P21127	CDK11B	P50613	CDK7	S398	P396S	396	Missense	proximal	-2	no	17.481	17.802	EPSD	COSMIC	13.598	Up-regulation
CMGC_CDK_CDK7_CDK7_ST	P21127	CDK11B	P50613	CDK7	S398	G404V	404	Missense	distal	6	no	17.481	18.141	EPSD	COSMIC	13.598	Up-regulation
CMGC_CDK_CDK7_CDK7_ST	P21127	CDK11B	P50613	CDK7	S414	S414L	414	Missense	central	0	yes	17.696	0.000	EPSD	COSMIC	13.598	Loss
CMGC_CDK_CDK7_CDK7_ST	P21127	CDK11B	P50613	CDK7	S414	D409N	409	Missense	distal	-5	no	17.696	16.835	EPSD	COSMIC	13.598	Down-regulation
CMGC_CDK_CDK7_CDK7_ST	P21127	CDK11B	P50613	CDK7	S414	D409Y	409	Missense	distal	-5	no	17.696	17.650	EPSD	COSMIC	13.598	Down-regulation
CMGC_CDK_CDK7_CDK7_ST	P21127	CDK11B	P50613	CDK7	S482	T481M	481	Missense	proximal	-1	no	21.519	21.668	EPSD	COSMIC	13.598	Up-regulation
CMGC_CDK_CDK7_CDK7_ST	P21127	CDK11B	P50613	CDK7	S482	E485K	485	Missense	distal	3	no	21.519	21.879	EPSD	COSMIC	13.598	Up-regulation
CMGC_CDK_CDK7_CDK7_ST	P21127	CDK11B	P50613	CDK7	T488	T481M	481	Missense	distal	-7	no	21.124	20.032	EPSD	COSMIC	13.598	Down-regulation
CMGC_CDK_CDK7_CDK7_ST	P21127	CDK11B	P50613	CDK7	T488	P495H	495	Missense	distal	7	no	21.124	18.112	EPSD	COSMIC	13.598	Down-regulation
CMGC_CDK_CDK7_CDK7_ST	P21127	CDK11B	P50613	CDK7	T488	L490F	490	Missense	proximal	2	no	21.124	22.703	EPSD	COSMIC	13.598	Up-regulation
CMGC_CDK_CDK7_CDK7_ST	P21127	CDK11B	P50613	CDK7	T488	K491E	491	Missense	distal	3	no	21.124	20.765	EPSD	COSMIC	13.598	Down-regulation
CMGC_CDK_CDK7_CDK7_ST	P21127	CDK11B	P50613	CDK7	T488	A492G	492	Missense	distal	4	no	21.124	20.476	EPSD	COSMIC	13.598	Down-regulation
CMGC_CDK_CDK7_CDK7_ST	P21127	CDK11B	P50613	CDK7	T488	E485K	485	Missense	distal	-3	no	21.124	18.630	EPSD	COSMIC	13.598	Down-regulation
CMGC_CDK_CDK7_CDK7_ST	P21127	CDK11B	P50613	CDK7	S589	L591Q	591	Missense	proximal	2	no	16.934	16.632	EPSD	COSMIC	13.598	Down-regulation
CMGC_CDK_CDK7_CDK7_ST	P21127	CDK11B	P50613	CDK7	S589	A584T	584	Missense	distal	-5	no	16.934	17.690	EPSD	COSMIC	13.598	Up-regulation
CMGC_CDK_CDK7_CDK7_ST	P21127	CDK11B	P50613	CDK7	S589	S589F	589	Missense	central	0	yes	16.934	0.000	EPSD	COSMIC	13.598	Loss
CMGC_CDK_CDK7_CDK7_ST	P21127	CDK11B	P50613	CDK7	S589	A593S	593	Missense	distal	4	no	16.934	16.082	EPSD	COSMIC	13.598	Down-regulation
CMGC_CDK_CDK7_CDK7_ST	P21127	CDK11B	P50613	CDK7	S589	T595A	595	Missense	distal	6	no	16.934	18.643	EPSD	COSMIC	13.598	Up-regulation
CMGC_CDK_CDK7_CDK7_ST	P21127	CDK11B	P50613	CDK7	S589	G582R	582	Missense	distal	-7	no	16.934	16.638	EPSD	COSMIC	13.598	Down-regulation
CMGC_CDK_CDK7_CDK7_ST	P21127	CDK11B	P50613	CDK7	S589	T595N	595	Missense	distal	6	no	16.934	16.807	EPSD	COSMIC	13.598	Down-regulation
CMGC_CDK_CDK7_CDK7_ST	P21127	CDK11B	P50613	CDK7	S589	A584S	584	Missense	distal	-5	no	16.934	18.989	EPSD	COSMIC	13.598	Up-regulation
CMGC_CDK_CDK7_CDK7_ST	P21127	CDK11B	P50613	CDK7	S589	P590S	590	Missense	proximal	1	no	16.934	8.401	EPSD	COSMIC	13.598	Loss
CMGC_CDK_CDK7_CDK7_ST	P21127	CDK11B	P50613	CDK7	S589	T595I	595	Missense	distal	6	no	16.934	16.885	EPSD	COSMIC	13.598	Down-regulation
CMGC_CDK_CDK7_CDK7_ST	P21127	CDK11B	P50613	CDK7	S589	R585Q	585	Missense	distal	-4	no	16.934	16.899	EPSD	COSMIC	13.598	Down-regulation
CMGC_CDK_CDK7_CDK7_ST	P21127	CDK11B	P50613	CDK7	S589	E586D	586	Missense	distal	-3	no	16.934	11.905	EPSD	COSMIC	13.598	Loss
CMGC_CDK_CDK7_CDK7_ST	P21127	CDK11B	P50613	CDK7	S589	G582V	582	Missense	distal	-7	no	16.934	15.472	EPSD	COSMIC	13.598	Down-regulation
CMGC_CDK_CDK7_CDK7_ST	P21127	CDK11B	P50613	CDK7	T595	L591Q	591	Missense	distal	-4	no	42.239	42.124	PhosphoSitePlus	COSMIC	13.598	Down-regulation
CMGC_CDK_CDK7_CDK7_ST	P21127	CDK11B	P50613	CDK7	T595	S589F	589	Missense	distal	-6	no	42.239	41.824	PhosphoSitePlus	COSMIC	13.598	Down-regulation
CMGC_CDK_CDK7_CDK7_ST	P21127	CDK11B	P50613	CDK7	T595	L601Q	601	Missense	distal	6	no	42.239	41.842	PhosphoSitePlus	COSMIC	13.598	Down-regulation
CMGC_CDK_CDK7_CDK7_ST	P21127	CDK11B	P50613	CDK7	T595	A593S	593	Missense	proximal	-2	no	42.239	42.437	PhosphoSitePlus	COSMIC	13.598	Up-regulation
CMGC_CDK_CDK7_CDK7_ST	P21127	CDK11B	P50613	CDK7	T595	T595A	595	Missense	central	0	yes	42.239	0.000	PhosphoSitePlus	COSMIC	13.598	Loss
CMGC_CDK_CDK7_CDK7_ST	P21127	CDK11B	P50613	CDK7	T595	T595N	595	Missense	central	0	yes	42.239	0.000	PhosphoSitePlus	COSMIC	13.598	Loss
CMGC_CDK_CDK7_CDK7_ST	P21127	CDK11B	P50613	CDK7	T595	P590S	590	Missense	distal	-5	no	42.239	42.392	PhosphoSitePlus	COSMIC	13.598	Up-regulation
CMGC_CDK_CDK7_CDK7_ST	P21127	CDK11B	P50613	CDK7	T595	T595I	595	Missense	central	0	yes	42.239	0.000	PhosphoSitePlus	COSMIC	13.598	Loss
CMGC_CDK_CDK7_CDK7_ST	P49736	MCM2	P50613	CDK7	S27	R33W	33	Missense	distal	6	no	18.849	16.376	EPSD;PhosphoSitePlus	COSMIC	13.598	Down-regulation
CMGC_CDK_CDK7_CDK7_ST	P49736	MCM2	P50613	CDK7	S27	R34H	34	Missense	distal	7	no	18.849	16.914	EPSD;PhosphoSitePlus	COSMIC	13.598	Down-regulation
CMGC_CDK_CDK7_CDK7_ST	P49736	MCM2	P50613	CDK7	S40	R33W	33	Missense	distal	-7	no	22.651	23.802	EPSD;PhosphoSitePlus	COSMIC	13.598	Up-regulation
CMGC_CDK_CDK7_CDK7_ST	P49736	MCM2	P50613	CDK7	S40	T39I	39	Missense	proximal	-1	no	22.651	22.673	EPSD;PhosphoSitePlus	COSMIC;GDSC	13.598	Up-regulation
CMGC_CDK_CDK7_CDK7_ST	P49736	MCM2	P50613	CDK7	S40	R34H	34	Missense	distal	-6	no	22.651	21.939	EPSD;PhosphoSitePlus	COSMIC	13.598	Down-regulation
CMGC_CDK_CDK7_CDK7_ST	P49736	MCM2	P50613	CDK7	S41	T39I	39	Missense	proximal	-2	no	22.804	23.070	EPSD;PhosphoSitePlus	COSMIC;GDSC	13.598	Up-regulation
CMGC_CDK_CDK7_CDK7_ST	P49736	MCM2	P50613	CDK7	S41	R34H	34	Missense	distal	-7	no	22.804	23.561	EPSD;PhosphoSitePlus	COSMIC	13.598	Up-regulation
CMGC_CDK_CDK7_CDK7_ST	P49736	MCM2	P50613	CDK7	S53	F49C	49	Missense	distal	-4	no	21.071	20.399	EPSD;PhosphoSitePlus	COSMIC	13.598	Down-regulation
CMGC_CDK_CDK7_CDK7_ST	P49736	MCM2	P50613	CDK7	S53	E54V	54	Missense	proximal	1	no	21.071	11.910	EPSD;PhosphoSitePlus	COSMIC	13.598	Loss
CMGC_CDK_CDK7_CDK7_ST	P49736	MCM2	P50613	CDK7	T59	E54V	54	Missense	distal	-5	no	23.482	19.900	EPSD;PhosphoSitePlus	COSMIC	13.598	Down-regulation
CMGC_CDK_CDK7_CDK7_ST	P49736	MCM2	P50613	CDK7	S108	E104K	104	Missense	distal	-4	no	26.698	27.447	EPSD;PhosphoSitePlus	COSMIC	13.598	Up-regulation
CMGC_CDK_CDK7_CDK7_ST	P49736	MCM2	P50613	CDK7	S108	R115W	115	Missense	distal	7	no	26.698	27.661	EPSD;PhosphoSitePlus	COSMIC	13.598	Up-regulation
CMGC_CDK_CDK7_CDK7_ST	P49736	MCM2	P50613	CDK7	S108	S108R	108	Missense	central	0	yes	26.698	0.000	EPSD;PhosphoSitePlus	COSMIC	13.598	Loss
CMGC_CDK_CDK7_CDK7_ST	P49736	MCM2	P50613	CDK7	S108	V102I	102	Missense	distal	-6	no	26.698	26.693	EPSD;PhosphoSitePlus	COSMIC	13.598	Down-regulation
CMGC_CDK_CDK7_CDK7_ST	P49736	MCM2	P50613	CDK7	S108	A112T	112	Missense	distal	4	no	26.698	26.230	EPSD;PhosphoSitePlus	COSMIC;GDSC;CCLE	13.598	Down-regulation
CMGC_CDK_CDK7_CDK7_ST	P49736	MCM2	P50613	CDK7	S139	R132P	132	Missense	distal	-7	no	21.705	21.675	EPSD;PhosphoSitePlus	COSMIC	13.598	Down-regulation
CMGC_CDK_CDK7_CDK7_ST	P49736	MCM2	P50613	CDK7	S139	R146C	146	Missense	distal	7	no	21.705	20.519	EPSD;PhosphoSitePlus	COSMIC	13.598	Down-regulation
CMGC_CDK_CDK7_CDK7_ST	P49736	MCM2	P50613	CDK7	S813	M814T	814	Missense	proximal	1	no	17.979	23.135	EPSD	COSMIC	13.598	Up-regulation
CMGC_CDK_CDK7_CDK7_ST	P49736	MCM2	P50613	CDK7	S813	V810I	810	Missense	distal	-3	no	17.979	18.143	EPSD	COSMIC;GDSC	13.598	Up-regulation
CMGC_CDK_CDK7_CDK7_ST	P49736	MCM2	P50613	CDK7	S813	M811T	811	Missense	proximal	-2	no	17.979	18.091	EPSD	COSMIC	13.598	Up-regulation
CMGC_CDK_CDK7_CDK7_ST	P24941	CDK2	P50613	CDK7	T41	K34N	34	Missense	distal	-7	no	14.399	11.871	EPSD	COSMIC	13.598	Loss
CMGC_CDK_CDK7_CDK7_ST	P24941	CDK2	P50613	CDK7	T41	P45L	45	Missense	distal	4	no	14.399	12.825	EPSD	COSMIC	13.598	Loss
CMGC_CDK_CDK7_CDK7_ST	P24941	CDK2	P50613	CDK7	T41	E42K	42	Missense	proximal	1	no	14.399	9.728	EPSD	COSMIC	13.598	Loss
CMGC_CDK_CDK7_CDK7_ST	P24941	CDK2	P50613	CDK7	S46	P45L	45	Missense	proximal	-1	no	21.025	20.997	EPSD;PhosphoSitePlus	COSMIC	13.598	Down-regulation
CMGC_CDK_CDK7_CDK7_ST	P24941	CDK2	P50613	CDK7	S46	E42K	42	Missense	distal	-4	no	21.025	21.774	EPSD;PhosphoSitePlus	COSMIC	13.598	Up-regulation
CMGC_CDK_CDK7_CDK7_ST	P24941	CDK2	P50613	CDK7	T160	P155S	155	Missense	distal	-5	no	33.784	33.937	EPSD;PhosphoSitePlus	COSMIC	13.598	Up-regulation
CMGC_CDK_CDK7_CDK7_ST	P24941	CDK2	P50613	CDK7	T160	V164L	164	Missense	distal	4	no	33.784	33.946	EPSD;PhosphoSitePlus	COSMIC	13.598	Up-regulation
CMGC_CDK_CDK7_CDK7_ST	P24941	CDK2	P50613	CDK7	T165	V164L	164	Missense	proximal	-1	no	21.011	21.050	EPSD;PhosphoSitePlus	COSMIC	13.598	Up-regulation
CMGC_CDK_CDK7_CDK7_ST	P24941	CDK2	P50613	CDK7	S207	D210N	210	Missense	distal	3	no	14.875	13.656	EPSD	COSMIC	13.598	Down-regulation
CMGC_CDK_CDK7_CDK7_ST	P24941	CDK2	P50613	CDK7	S207	R200W	200	Missense	distal	-7	no	14.875	16.026	EPSD	COSMIC	13.598	Up-regulation
CMGC_CDK_CDK7_CDK7_ST	P24941	CDK2	P50613	CDK7	S207	P204S	204	Missense	distal	-3	no	14.875	14.466	EPSD	COSMIC	13.598	Down-regulation
CMGC_CDK_CDK7_CDK7_ST	P24941	CDK2	P50613	CDK7	S207	P204T	204	Missense	distal	-3	no	14.875	14.651	EPSD	COSMIC	13.598	Down-regulation
CMGC_CDK_CDK7_CDK7_ST	P24941	CDK2	P50613	CDK7	S207	R214W	214	Missense	distal	7	no	14.875	15.838	EPSD	COSMIC	13.598	Up-regulation
CMGC_CDK_CDK7_CDK7_ST	P24941	CDK2	P50613	CDK7	S261	R260Q	260	Missense	proximal	-1	no	16.686	17.129	EPSD	COSMIC	13.598	Up-regulation
CMGC_CDK_CDK7_CDK7_ST	P03372	ESR1	P50613	CDK7	S102	F97L	97	Missense	distal	-5	no	15.152	15.610	EPSD	COSMIC	13.598	Up-regulation
CMGC_CDK_CDK7_CDK7_ST	P03372	ESR1	P50613	CDK7	S102	M109T	109	Missense	distal	7	no	15.152	12.299	EPSD	COSMIC	13.598	Loss
CMGC_CDK_CDK7_CDK7_ST	P03372	ESR1	P50613	CDK7	S106	P113L	113	Missense	distal	7	no	17.012	12.341	EPSD	COSMIC	13.598	Loss
CMGC_CDK_CDK7_CDK7_ST	P03372	ESR1	P50613	CDK7	S106	P113Q	113	Missense	distal	7	no	17.012	15.364	EPSD	COSMIC	13.598	Down-regulation
CMGC_CDK_CDK7_CDK7_ST	P03372	ESR1	P50613	CDK7	S106	H112L	112	Missense	distal	6	no	17.012	17.187	EPSD	COSMIC	13.598	Up-regulation
CMGC_CDK_CDK7_CDK7_ST	P03372	ESR1	P50613	CDK7	S106	M109T	109	Missense	distal	3	no	17.012	17.354	EPSD	COSMIC	13.598	Up-regulation
CMGC_CDK_CDK7_CDK7_ST	P03372	ESR1	P50613	CDK7	S118	P113L	113	Missense	distal	-5	no	23.487	22.044	PhosphoSitePlus	COSMIC	13.598	Down-regulation
CMGC_CDK_CDK7_CDK7_ST	P03372	ESR1	P50613	CDK7	S118	P113Q	113	Missense	distal	-5	no	23.487	22.060	PhosphoSitePlus	COSMIC	13.598	Down-regulation
CMGC_CDK_CDK7_CDK7_ST	P03372	ESR1	P50613	CDK7	S118	L117Q	117	Missense	proximal	-1	no	23.487	23.738	PhosphoSitePlus	COSMIC	13.598	Up-regulation
CMGC_CDK_CDK7_CDK7_ST	P03372	ESR1	P50613	CDK7	S118	H112L	112	Missense	distal	-6	no	23.487	24.231	PhosphoSitePlus	COSMIC	13.598	Up-regulation
CMGC_CDK_CDK7_CDK7_ST	P03372	ESR1	P50613	CDK7	S118	S118P	118	Missense	central	0	yes	23.487	0.000	PhosphoSitePlus	COSMIC	13.598	Loss
CMGC_CDK_CDK7_CDK7_ST	P03372	ESR1	P50613	CDK7	T574	S578Y	578	Missense	distal	4	no	19.161	20.437	EPSD	COSMIC	13.598	Up-regulation
CMGC_CDK_CDK7_CDK7_ST	P03372	ESR1	P50613	CDK7	S575	S578Y	578	Missense	distal	3	no	15.227	15.898	EPSD	COSMIC	13.598	Up-regulation
CMGC_CDK_CDK7_CDK7_ST	Q00534	CDK6	P50613	CDK7	S57	V64M	64	Missense	distal	7	no	12.588	14.576	EPSD	COSMIC	13.598	Gain
CMGC_CDK_CDK7_CDK7_ST	Q00534	CDK6	P50613	CDK7	S171	G165S	165	Missense	distal	-6	no	13.059	13.851	EPSD	COSMIC	13.598	Gain
CMGC_CDK_CDK7_CDK7_ST	Q00534	CDK6	P50613	CDK7	T177	Y170C	170	Missense	distal	-7	no	29.096	27.572	PhosphoSitePlus	COSMIC	13.598	Down-regulation
CMGC_CDK_CDK7_CDK7_ST	Q00534	CDK6	P50613	CDK7	T177	F172L	172	Missense	distal	-5	no	29.096	29.554	PhosphoSitePlus	COSMIC	13.598	Up-regulation
CMGC_CDK_CDK7_CDK7_ST	Q00534	CDK6	P50613	CDK7	T177	A175V	175	Missense	proximal	-2	no	29.096	28.791	PhosphoSitePlus	COSMIC	13.598	Down-regulation
CMGC_CDK_CDK7_CDK7_ST	Q00534	CDK6	P50613	CDK7	S317	D311V	311	Missense	distal	-6	no	14.253	14.459	EPSD	COSMIC	13.598	Up-regulation
CMGC_CDK_CDK7_CDK7_ST	Q00534	CDK6	P50613	CDK7	S317	L310P	310	Missense	distal	-7	no	14.253	13.417	EPSD	COSMIC	13.598	Loss
CMGC_CDK_CDK7_CDK7_ST	P04637	TP53	P50613	CDK7	S33	M40I	40	Missense	distal	7	no	20.872	20.736	EPSD;PhosphoSitePlus	COSMIC	13.598	Down-regulation
CMGC_CDK_CDK7_CDK7_ST	P04637	TP53	P50613	CDK7	S33	V31I	31	Missense	proximal	-2	no	20.872	21.150	EPSD;PhosphoSitePlus	COSMIC;GDSC;CCLE	13.598	Up-regulation
CMGC_CDK_CDK7_CDK7_ST	P04637	TP53	P50613	CDK7	S33	P36L	36	Missense	distal	3	no	20.872	19.863	EPSD;PhosphoSitePlus	COSMIC;GDSC;CCLE	13.598	Down-regulation
CMGC_CDK_CDK7_CDK7_ST	P04637	TP53	P50613	CDK7	S33	L35F	35	Missense	proximal	2	no	20.872	22.451	EPSD;PhosphoSitePlus	COSMIC	13.598	Up-regulation
CMGC_CDK_CDK7_CDK7_ST	P04637	TP53	P50613	CDK7	S33	Q38L	38	Missense	distal	5	no	20.872	20.414	EPSD;PhosphoSitePlus	COSMIC	13.598	Down-regulation
CMGC_CDK_CDK7_CDK7_ST	P04637	TP53	P50613	CDK7	S33	S37T	37	Missense	distal	4	no	20.872	21.256	EPSD;PhosphoSitePlus	COSMIC	13.598	Up-regulation
CMGC_CDK_CDK7_CDK7_ST	P04637	TP53	P50613	CDK7	S33	L26P	26	Missense	distal	-7	no	20.872	20.036	EPSD;PhosphoSitePlus	COSMIC	13.598	Down-regulation
CMGC_CDK_CDK7_CDK7_ST	P04637	TP53	P50613	CDK7	S33	P36S	36	Missense	distal	3	no	20.872	20.124	EPSD;PhosphoSitePlus	COSMIC;GDSC;CCLE	13.598	Down-regulation
CMGC_CDK_CDK7_CDK7_ST	P04637	TP53	P50613	CDK7	S33	A39V	39	Missense	distal	6	no	20.872	18.965	EPSD;PhosphoSitePlus	COSMIC	13.598	Down-regulation
CMGC_CDK_CDK7_CDK7_ST	P04637	TP53	P50613	CDK7	S33	A39S	39	Missense	distal	6	no	20.872	19.193	EPSD;PhosphoSitePlus	COSMIC	13.598	Down-regulation
CMGC_CDK_CDK7_CDK7_ST	P04637	TP53	P50613	CDK7	S33	N30K	30	Missense	distal	-3	no	20.872	22.808	EPSD;PhosphoSitePlus	COSMIC	13.598	Up-regulation
CMGC_CDK_CDK7_CDK7_ST	P04637	TP53	P50613	CDK7	S33	A39T	39	Missense	distal	6	no	20.872	19.162	EPSD;PhosphoSitePlus	COSMIC	13.598	Down-regulation
CMGC_CDK_CDK7_CDK7_ST	P04637	TP53	P50613	CDK7	S33	P27T	27	Missense	distal	-6	no	20.872	20.842	EPSD;PhosphoSitePlus	COSMIC	13.598	Down-regulation
CMGC_CDK_CDK7_CDK7_ST	P04637	TP53	P50613	CDK7	S33	P36R	36	Missense	distal	3	no	20.872	20.826	EPSD;PhosphoSitePlus	COSMIC	13.598	Down-regulation
CMGC_CDK_CDK7_CDK7_ST	P04637	TP53	P50613	CDK7	S33	L35R	35	Missense	proximal	2	no	20.872	22.581	EPSD;PhosphoSitePlus	COSMIC	13.598	Up-regulation
CMGC_CDK_CDK7_CDK7_ST	P04637	TP53	P50613	CDK7	S33	L35H	35	Missense	proximal	2	no	20.872	22.891	EPSD;PhosphoSitePlus	COSMIC	13.598	Up-regulation
CMGC_CDK_CDK7_CDK7_ST	P04637	TP53	P50613	CDK7	S33	L35P	35	Missense	proximal	2	no	20.872	21.287	EPSD;PhosphoSitePlus	COSMIC	13.598	Up-regulation
CMGC_CDK_CDK7_CDK7_ST	P04637	TP53	P50613	CDK7	S33	L35I	35	Missense	proximal	2	no	20.872	21.971	EPSD;PhosphoSitePlus	COSMIC	13.598	Up-regulation
CMGC_CDK_CDK7_CDK7_ST	P04637	TP53	P50613	CDK7	S33	L35V	35	Missense	proximal	2	no	20.872	21.527	EPSD;PhosphoSitePlus	COSMIC	13.598	Up-regulation
CMGC_CDK_CDK7_CDK7_ST	P04637	TP53	P50613	CDK7	S46	M40I	40	Missense	distal	-6	no	15.372	15.482	EPSD	COSMIC	13.598	Up-regulation
CMGC_CDK_CDK7_CDK7_ST	P04637	TP53	P50613	CDK7	S46	W53C	53	Missense	distal	7	no	15.372	13.223	EPSD	COSMIC	13.598	Loss
CMGC_CDK_CDK7_CDK7_ST	P04637	TP53	P50613	CDK7	S46	W53G	53	Missense	distal	7	no	15.372	14.221	EPSD	COSMIC	13.598	Down-regulation
CMGC_CDK_CDK7_CDK7_ST	P04637	TP53	P50613	CDK7	S46	S46F	46	Missense	central	0	yes	15.372	0.000	EPSD	COSMIC	13.598	Loss
CMGC_CDK_CDK7_CDK7_ST	P04637	TP53	P50613	CDK7	S46	D49Y	49	Missense	distal	3	no	15.372	14.515	EPSD	COSMIC	13.598	Down-regulation
CMGC_CDK_CDK7_CDK7_ST	P04637	TP53	P50613	CDK7	S46	P47L	47	Missense	proximal	1	no	15.372	7.901	EPSD	COSMIC	13.598	Loss
CMGC_CDK_CDK7_CDK7_ST	P04637	TP53	P50613	CDK7	S46	D49H	49	Missense	distal	3	no	15.372	13.705	EPSD	COSMIC;GDSC;CCLE	13.598	Down-regulation
CMGC_CDK_CDK7_CDK7_ST	P04637	TP53	P50613	CDK7	S46	P47S	47	Missense	proximal	1	no	15.372	6.839	EPSD	COSMIC	13.598	Loss
CMGC_CDK_CDK7_CDK7_ST	P04637	TP53	P50613	CDK7	S46	D41N	41	Missense	distal	-5	no	15.372	14.511	EPSD	COSMIC	13.598	Down-regulation
CMGC_CDK_CDK7_CDK7_ST	P04637	TP53	P50613	CDK7	S46	D48H	48	Missense	proximal	2	no	15.372	16.144	EPSD	COSMIC	13.598	Up-regulation
CMGC_CDK_CDK7_CDK7_ST	P04637	TP53	P50613	CDK7	S46	D49N	49	Missense	distal	3	no	15.372	14.153	EPSD	COSMIC	13.598	Down-regulation
CMGC_CDK_CDK7_CDK7_ST	P04637	TP53	P50613	CDK7	S46	M44I	44	Missense	proximal	-2	no	15.372	15.749	EPSD	COSMIC	13.598	Up-regulation
CMGC_CDK_CDK7_CDK7_ST	P04637	TP53	P50613	CDK7	S46	Q52H	52	Missense	distal	6	no	15.372	15.594	EPSD	COSMIC	13.598	Up-regulation
CMGC_CDK_CDK7_CDK7_ST	P04637	TP53	P50613	CDK7	S46	D49V	49	Missense	distal	3	no	15.372	13.733	EPSD	COSMIC	13.598	Down-regulation
CMGC_CDK_CDK7_CDK7_ST	P04637	TP53	P50613	CDK7	S46	A39V	39	Missense	distal	-7	no	15.372	16.650	EPSD	COSMIC	13.598	Up-regulation
CMGC_CDK_CDK7_CDK7_ST	P04637	TP53	P50613	CDK7	S46	A39S	39	Missense	distal	-7	no	15.372	15.709	EPSD	COSMIC	13.598	Up-regulation
CMGC_CDK_CDK7_CDK7_ST	P04637	TP53	P50613	CDK7	S46	D42Y	42	Missense	distal	-4	no	15.372	15.193	EPSD	COSMIC	13.598	Down-regulation
CMGC_CDK_CDK7_CDK7_ST	P04637	TP53	P50613	CDK7	S46	M44R	44	Missense	proximal	-2	no	15.372	15.443	EPSD	COSMIC	13.598	Up-regulation
CMGC_CDK_CDK7_CDK7_ST	P04637	TP53	P50613	CDK7	S46	S46P	46	Missense	central	0	yes	15.372	0.000	EPSD	COSMIC	13.598	Loss
CMGC_CDK_CDK7_CDK7_ST	P04637	TP53	P50613	CDK7	S46	M44V	44	Missense	proximal	-2	no	15.372	15.471	EPSD	COSMIC	13.598	Up-regulation
CMGC_CDK_CDK7_CDK7_ST	P04637	TP53	P50613	CDK7	S46	L45P	45	Missense	proximal	-1	no	15.372	15.400	EPSD	COSMIC	13.598	Up-regulation
CMGC_CDK_CDK7_CDK7_ST	P04637	TP53	P50613	CDK7	S46	M44T	44	Missense	proximal	-2	no	15.372	15.484	EPSD	COSMIC	13.598	Up-regulation
CMGC_CDK_CDK7_CDK7_ST	P04637	TP53	P50613	CDK7	S46	A39T	39	Missense	distal	-7	no	15.372	17.190	EPSD	COSMIC	13.598	Up-regulation
CMGC_CDK_CDK7_CDK7_ST	P04637	TP53	P50613	CDK7	S46	L43F	43	Missense	distal	-3	no	15.372	13.894	EPSD	COSMIC	13.598	Down-regulation
CMGC_CDK_CDK7_CDK7_ST	P04637	TP53	P50613	CDK7	S46	D41H	41	Missense	distal	-5	no	15.372	13.796	EPSD	COSMIC	13.598	Down-regulation
CMGC_CDK_CDK7_CDK7_ST	P04637	TP53	P50613	CDK7	S46	D49E	49	Missense	distal	3	no	15.372	13.900	EPSD	COSMIC	13.598	Down-regulation
CMGC_CDK_CDK7_CDK7_ST	P04637	TP53	P50613	CDK7	S46	D49G	49	Missense	distal	3	no	15.372	13.795	EPSD	COSMIC	13.598	Down-regulation
CMGC_CDK_CDK7_CDK7_ST	P04637	TP53	P50613	CDK7	S46	D48A	48	Missense	proximal	2	no	15.372	13.680	EPSD	COSMIC	13.598	Down-regulation
CMGC_CDK_CDK7_CDK7_ST	P04637	TP53	P50613	CDK7	S46	D48Y	48	Missense	proximal	2	no	15.372	15.530	EPSD	COSMIC	13.598	Up-regulation
CMGC_CDK_CDK7_CDK7_ST	P04637	TP53	P50613	CDK7	S46	D48E	48	Missense	proximal	2	no	15.372	13.857	EPSD	COSMIC	13.598	Down-regulation
CMGC_CDK_CDK7_CDK7_ST	P04637	TP53	P50613	CDK7	S46	D49I	49	Missense	distal	3	no	15.372	13.996	EPSD	COSMIC	13.598	Down-regulation
CMGC_CDK_CDK7_CDK7_ST	P04637	TP53	P50613	CDK7	S46	D41E	41	Missense	distal	-5	no	15.372	17.611	EPSD	COSMIC	13.598	Up-regulation
CMGC_CDK_CDK7_CDK7_ST	P04637	TP53	P50613	CDK7	T81	P77A	77	Missense	distal	-4	no	16.811	16.754	EPSD	COSMIC	13.598	Down-regulation
CMGC_CDK_CDK7_CDK7_ST	P04637	TP53	P50613	CDK7	T81	A76T	76	Missense	distal	-5	no	16.811	17.567	EPSD	COSMIC	13.598	Up-regulation
CMGC_CDK_CDK7_CDK7_ST	P04637	TP53	P50613	CDK7	T81	A83T	83	Missense	proximal	2	no	16.811	17.537	EPSD	COSMIC	13.598	Up-regulation
CMGC_CDK_CDK7_CDK7_ST	P04637	TP53	P50613	CDK7	T81	T81I	81	Missense	central	0	yes	16.811	0.000	EPSD	COSMIC	13.598	Loss
CMGC_CDK_CDK7_CDK7_ST	P04637	TP53	P50613	CDK7	T81	A84V	84	Missense	distal	3	no	16.811	16.946	EPSD	COSMIC	13.598	Up-regulation
CMGC_CDK_CDK7_CDK7_ST	P04637	TP53	P50613	CDK7	T81	P80L	80	Missense	proximal	-1	no	16.811	16.783	EPSD	COSMIC	13.598	Down-regulation
CMGC_CDK_CDK7_CDK7_ST	P04637	TP53	P50613	CDK7	T81	A86V	86	Missense	distal	5	no	16.811	14.769	EPSD	COSMIC	13.598	Down-regulation
CMGC_CDK_CDK7_CDK7_ST	P04637	TP53	P50613	CDK7	T81	P85S	85	Missense	distal	4	no	16.811	14.661	EPSD	COSMIC	13.598	Down-regulation
CMGC_CDK_CDK7_CDK7_ST	P04637	TP53	P50613	CDK7	T81	A79T	79	Missense	proximal	-2	no	16.811	16.518	EPSD	COSMIC	13.598	Down-regulation
CMGC_CDK_CDK7_CDK7_ST	P04637	TP53	P50613	CDK7	T81	A84G	84	Missense	distal	3	no	16.811	17.007	EPSD	COSMIC	13.598	Up-regulation
CMGC_CDK_CDK7_CDK7_ST	P04637	TP53	P50613	CDK7	T81	A78V	78	Missense	distal	-3	no	16.811	13.801	EPSD	COSMIC	13.598	Down-regulation
CMGC_CDK_CDK7_CDK7_ST	P04637	TP53	P50613	CDK7	T81	A78S	78	Missense	distal	-3	no	16.811	14.860	EPSD	COSMIC	13.598	Down-regulation
CMGC_CDK_CDK7_CDK7_ST	P04637	TP53	P50613	CDK7	T81	P87L	87	Missense	distal	6	no	16.811	17.257	EPSD	COSMIC	13.598	Up-regulation
CMGC_CDK_CDK7_CDK7_ST	P04637	TP53	P50613	CDK7	T81	P85L	85	Missense	distal	4	no	16.811	15.237	EPSD	COSMIC	13.598	Down-regulation
CMGC_CDK_CDK7_CDK7_ST	P04637	TP53	P50613	CDK7	T81	P82S	82	Missense	proximal	1	no	16.811	8.278	EPSD	COSMIC	13.598	Loss
CMGC_CDK_CDK7_CDK7_ST	P04637	TP53	P50613	CDK7	T81	P77S	77	Missense	distal	-4	no	16.811	16.616	EPSD	COSMIC	13.598	Down-regulation
CMGC_CDK_CDK7_CDK7_ST	P04637	TP53	P50613	CDK7	T81	P80S	80	Missense	proximal	-1	no	16.811	17.065	EPSD	COSMIC	13.598	Up-regulation
CMGC_CDK_CDK7_CDK7_ST	P04637	TP53	P50613	CDK7	T81	A84T	84	Missense	distal	3	no	16.811	17.586	EPSD	COSMIC	13.598	Up-regulation
CMGC_CDK_CDK7_CDK7_ST	P04637	TP53	P50613	CDK7	T81	A83E	83	Missense	proximal	2	no	16.811	16.988	EPSD	COSMIC	13.598	Up-regulation
CMGC_CDK_CDK7_CDK7_ST	P04637	TP53	P50613	CDK7	T81	P85T	85	Missense	distal	4	no	16.811	15.045	EPSD	COSMIC	13.598	Down-regulation
CMGC_CDK_CDK7_CDK7_ST	P04637	TP53	P50613	CDK7	T81	A74V	74	Missense	distal	-7	no	16.811	18.089	EPSD	COSMIC	13.598	Up-regulation
CMGC_CDK_CDK7_CDK7_ST	P04637	TP53	P50613	CDK7	T81	P75S	75	Missense	distal	-6	no	16.811	17.210	EPSD	COSMIC	13.598	Up-regulation
CMGC_CDK_CDK7_CDK7_ST	P04637	TP53	P50613	CDK7	T81	A76V	76	Missense	distal	-5	no	16.811	15.528	EPSD	COSMIC	13.598	Down-regulation
CMGC_CDK_CDK7_CDK7_ST	P04637	TP53	P50613	CDK7	T81	P75R	75	Missense	distal	-6	no	16.811	16.758	EPSD	COSMIC	13.598	Down-regulation
CMGC_CDK_CDK7_CDK7_ST	P04637	TP53	P50613	CDK7	T81	P87H	87	Missense	distal	6	no	16.811	17.082	EPSD	COSMIC	13.598	Up-regulation
CMGC_CDK_CDK7_CDK7_ST	P04637	TP53	P50613	CDK7	T81	P87T	87	Missense	distal	6	no	16.811	16.414	EPSD	COSMIC	13.598	Down-regulation
CMGC_CDK_CDK7_CDK7_ST	P04637	TP53	P50613	CDK7	T81	P87S	87	Missense	distal	6	no	16.811	16.445	EPSD	COSMIC	13.598	Down-regulation
CMGC_CDK_CDK7_CDK7_ST	P04637	TP53	P50613	CDK7	T81	P87R	87	Missense	distal	6	no	16.811	17.756	EPSD	COSMIC	13.598	Up-regulation
CMGC_CDK_CDK7_CDK7_ST	P04637	TP53	P50613	CDK7	T81	P87C	87	Missense	distal	6	no	16.811	16.558	EPSD	COSMIC	13.598	Down-regulation
CMGC_CDK_CDK7_CDK7_ST	P04637	TP53	P50613	CDK7	T81	A86E	86	Missense	distal	5	no	16.811	16.352	EPSD	COSMIC	13.598	Down-regulation
CMGC_CDK_CDK7_CDK7_ST	P04637	TP53	P50613	CDK7	T81	A86S	86	Missense	distal	5	no	16.811	17.454	EPSD	COSMIC	13.598	Up-regulation
CMGC_CDK_CDK7_CDK7_ST	P04637	TP53	P50613	CDK7	T81	A83V	83	Missense	proximal	2	no	16.811	17.911	EPSD	COSMIC	13.598	Up-regulation
CMGC_CDK_CDK7_CDK7_ST	P04637	TP53	P50613	CDK7	S127	C124W	124	Missense	distal	-3	no	17.259	15.338	EPSD	COSMIC	13.598	Down-regulation
CMGC_CDK_CDK7_CDK7_ST	P04637	TP53	P50613	CDK7	S127	C124F	124	Missense	distal	-3	no	17.259	16.902	EPSD	COSMIC	13.598	Down-regulation
CMGC_CDK_CDK7_CDK7_ST	P04637	TP53	P50613	CDK7	S127	C124S	124	Missense	distal	-3	no	17.259	17.931	EPSD	COSMIC	13.598	Up-regulation
CMGC_CDK_CDK7_CDK7_ST	P04637	TP53	P50613	CDK7	S127	S127A	127	Missense	central	0	yes	17.259	0.000	EPSD	COSMIC	13.598	Loss
CMGC_CDK_CDK7_CDK7_ST	P04637	TP53	P50613	CDK7	S127	S127L	127	Missense	central	0	yes	17.259	0.000	EPSD	COSMIC	13.598	Loss
CMGC_CDK_CDK7_CDK7_ST	P04637	TP53	P50613	CDK7	S127	C124T	124	Missense	distal	-3	no	17.259	18.116	EPSD	COSMIC	13.598	Up-regulation
CMGC_CDK_CDK7_CDK7_ST	P04637	TP53	P50613	CDK7	S127	S127I	127	Missense	central	0	yes	17.259	0.000	EPSD	COSMIC	13.598	Loss
CMGC_CDK_CDK7_CDK7_ST	P04637	TP53	P50613	CDK7	S127	S127G	127	Missense	central	0	yes	17.259	0.000	EPSD	COSMIC	13.598	Loss
CMGC_CDK_CDK7_CDK7_ST	P04637	TP53	P50613	CDK7	S127	N131H	131	Missense	distal	4	no	17.259	16.223	EPSD	COSMIC	13.598	Down-regulation
CMGC_CDK_CDK7_CDK7_ST	P04637	TP53	P50613	CDK7	S127	N131D	131	Missense	distal	4	no	17.259	18.965	EPSD	COSMIC	13.598	Up-regulation
CMGC_CDK_CDK7_CDK7_ST	P04637	TP53	P50613	CDK7	S127	T125I	125	Missense	proximal	-2	no	17.259	17.524	EPSD	COSMIC	13.598	Up-regulation
CMGC_CDK_CDK7_CDK7_ST	P04637	TP53	P50613	CDK7	S127	F134I	134	Missense	distal	7	no	17.259	16.762	EPSD	COSMIC	13.598	Down-regulation
CMGC_CDK_CDK7_CDK7_ST	P04637	TP53	P50613	CDK7	S127	K120T	120	Missense	distal	-7	no	17.259	15.004	EPSD	COSMIC	13.598	Down-regulation
CMGC_CDK_CDK7_CDK7_ST	P04637	TP53	P50613	CDK7	S127	F134S	134	Missense	distal	7	no	17.259	12.437	EPSD	COSMIC	13.598	Loss
CMGC_CDK_CDK7_CDK7_ST	P04637	TP53	P50613	CDK7	S127	T125K	125	Missense	proximal	-2	no	17.259	17.449	EPSD	COSMIC	13.598	Up-regulation
CMGC_CDK_CDK7_CDK7_ST	P04637	TP53	P50613	CDK7	S127	M133I	133	Missense	distal	6	no	17.259	16.030	EPSD	COSMIC	13.598	Down-regulation
CMGC_CDK_CDK7_CDK7_ST	P04637	TP53	P50613	CDK7	S127	N131K	131	Missense	distal	4	no	17.259	16.756	EPSD	COSMIC;CCLE	13.598	Down-regulation
CMGC_CDK_CDK7_CDK7_ST	P04637	TP53	P50613	CDK7	S127	P128S	128	Missense	proximal	1	no	17.259	8.725	EPSD	COSMIC	13.598	Loss
CMGC_CDK_CDK7_CDK7_ST	P04637	TP53	P50613	CDK7	S127	M133L	133	Missense	distal	6	no	17.259	16.921	EPSD	COSMIC	13.598	Down-regulation
CMGC_CDK_CDK7_CDK7_ST	P04637	TP53	P50613	CDK7	S127	A129T	129	Missense	proximal	2	no	17.259	17.985	EPSD	COSMIC	13.598	Up-regulation
CMGC_CDK_CDK7_CDK7_ST	P04637	TP53	P50613	CDK7	S127	T123I	123	Missense	distal	-4	no	17.259	17.797	EPSD	COSMIC	13.598	Up-regulation
CMGC_CDK_CDK7_CDK7_ST	P04637	TP53	P50613	CDK7	S127	A129G	129	Missense	proximal	2	no	17.259	18.166	EPSD	COSMIC	13.598	Up-regulation
CMGC_CDK_CDK7_CDK7_ST	P04637	TP53	P50613	CDK7	S127	K132W	132	Missense	distal	5	no	17.259	14.594	EPSD	COSMIC	13.598	Down-regulation
CMGC_CDK_CDK7_CDK7_ST	P04637	TP53	P50613	CDK7	S127	A129V	129	Missense	proximal	2	no	17.259	18.359	EPSD	COSMIC	13.598	Up-regulation
CMGC_CDK_CDK7_CDK7_ST	P04637	TP53	P50613	CDK7	S127	P128A	128	Missense	proximal	1	no	17.259	-1.495	EPSD	COSMIC	13.598	Loss
CMGC_CDK_CDK7_CDK7_ST	P04637	TP53	P50613	CDK7	S127	L130I	130	Missense	distal	3	no	17.259	17.671	EPSD	COSMIC	13.598	Up-regulation
CMGC_CDK_CDK7_CDK7_ST	P04637	TP53	P50613	CDK7	S127	S121F	121	Missense	distal	-6	no	17.259	16.843	EPSD	COSMIC	13.598	Down-regulation
CMGC_CDK_CDK7_CDK7_ST	P04637	TP53	P50613	CDK7	S127	A129D	129	Missense	proximal	2	no	17.259	18.951	EPSD	COSMIC	13.598	Up-regulation
CMGC_CDK_CDK7_CDK7_ST	P04637	TP53	P50613	CDK7	S127	K120Q	120	Missense	distal	-7	no	17.259	14.443	EPSD	COSMIC	13.598	Down-regulation
CMGC_CDK_CDK7_CDK7_ST	P04637	TP53	P50613	CDK7	S127	T125S	125	Missense	proximal	-2	no	17.259	17.750	EPSD	COSMIC	13.598	Up-regulation
CMGC_CDK_CDK7_CDK7_ST	P04637	TP53	P50613	CDK7	S127	P128L	128	Missense	proximal	1	no	17.259	9.788	EPSD	COSMIC	13.598	Loss
CMGC_CDK_CDK7_CDK7_ST	P04637	TP53	P50613	CDK7	S127	V122L	122	Missense	distal	-5	no	17.259	19.001	EPSD	COSMIC	13.598	Up-regulation
CMGC_CDK_CDK7_CDK7_ST	P04637	TP53	P50613	CDK7	S127	C124L	124	Missense	distal	-3	no	17.259	18.380	EPSD	COSMIC	13.598	Up-regulation
CMGC_CDK_CDK7_CDK7_ST	P04637	TP53	P50613	CDK7	S127	N131T	131	Missense	distal	4	no	17.259	16.051	EPSD	COSMIC	13.598	Down-regulation
CMGC_CDK_CDK7_CDK7_ST	P04637	TP53	P50613	CDK7	S127	M133V	133	Missense	distal	6	no	17.259	15.882	EPSD	COSMIC	13.598	Down-regulation
CMGC_CDK_CDK7_CDK7_ST	P04637	TP53	P50613	CDK7	T150	G154C	154	Missense	distal	4	no	11.571	13.935	EPSD	COSMIC	13.598	Gain
CMGC_CDK_CDK7_CDK7_ST	P04637	TP53	P50613	CDK7	T150	G154D	154	Missense	distal	4	no	11.571	14.666	EPSD	COSMIC	13.598	Gain
CMGC_CDK_CDK7_CDK7_ST	P04637	TP53	P50613	CDK7	T150	V147E	147	Missense	distal	-3	no	11.571	15.216	EPSD	COSMIC	13.598	Gain
CMGC_CDK_CDK7_CDK7_ST	P04637	TP53	P50613	CDK7	T150	V147A	147	Missense	distal	-3	no	11.571	14.581	EPSD	COSMIC	13.598	Gain
CMGC_CDK_CDK7_CDK7_ST	P04637	TP53	P50613	CDK7	T150	T155S	155	Missense	distal	5	no	11.571	13.792	EPSD	COSMIC;CCLE	13.598	Gain
CMGC_CDK_CDK7_CDK7_ST	P04637	TP53	P50613	CDK7	T150	G154R	154	Missense	distal	4	no	11.571	13.969	EPSD	COSMIC	13.598	Gain
CMGC_CDK_CDK7_CDK7_ST	P04637	TP53	P50613	CDK7	T155	P152A	152	Missense	distal	-3	no	12.335	13.877	EPSD	COSMIC	13.598	Gain
CMGC_CDK_CDK7_CDK7_ST	P04637	TP53	P50613	CDK7	T155	A159D	159	Missense	distal	4	no	12.335	14.782	EPSD	COSMIC;GDSC;CCLE	13.598	Gain
CMGC_CDK_CDK7_CDK7_ST	P04637	TP53	P50613	CDK7	T155	D148H	148	Missense	distal	-7	no	12.335	14.025	EPSD	COSMIC	13.598	Gain
CMGC_CDK_CDK7_CDK7_ST	P04637	TP53	P50613	CDK7	T155	D148Y	148	Missense	distal	-7	no	12.335	13.753	EPSD	COSMIC	13.598	Gain
CMGC_CDK_CDK7_CDK7_ST	P04637	TP53	P50613	CDK7	T211	D208E	208	Missense	distal	-3	no	10.423	15.453	EPSD	COSMIC	13.598	Gain
CMGC_CDK_CDK7_CDK7_ST	P04637	TP53	P50613	CDK7	S315	N310T	310	Missense	distal	-5	no	14.594	16.152	EPSD	COSMIC	13.598	Up-regulation
CMGC_CDK_CDK7_CDK7_ST	P04637	TP53	P50613	CDK7	S315	Q317R	317	Missense	proximal	2	no	14.594	16.605	EPSD	COSMIC	13.598	Up-regulation
CMGC_CDK_CDK7_CDK7_ST	P04637	TP53	P50613	CDK7	S315	P309S	309	Missense	distal	-6	no	14.594	14.993	EPSD	COSMIC;GDSC;CCLE	13.598	Up-regulation
CMGC_CDK_CDK7_CDK7_ST	P04637	TP53	P50613	CDK7	S315	K319E	319	Missense	distal	4	no	14.594	13.933	EPSD	COSMIC	13.598	Down-regulation
CMGC_CDK_CDK7_CDK7_ST	P04637	TP53	P50613	CDK7	S315	P322L	322	Missense	distal	7	no	14.594	9.923	EPSD	COSMIC	13.598	Loss
CMGC_CDK_CDK7_CDK7_ST	P04637	TP53	P50613	CDK7	S315	K320N	320	Missense	distal	5	no	14.594	15.051	EPSD	COSMIC;GDSC;CCLE	13.598	Up-regulation
CMGC_CDK_CDK7_CDK7_ST	P04637	TP53	P50613	CDK7	S315	N310L	310	Missense	distal	-5	no	14.594	15.855	EPSD	COSMIC	13.598	Up-regulation
CMGC_CDK_CDK7_CDK7_ST	P04637	TP53	P50613	CDK7	S315	T312S	312	Missense	distal	-3	no	14.594	14.410	EPSD	COSMIC	13.598	Down-regulation
CMGC_CDK_CDK7_CDK7_ST	P04637	TP53	P50613	CDK7	S315	N311Y	311	Missense	distal	-4	no	14.594	14.538	EPSD	COSMIC	13.598	Down-regulation
CMGC_CDK_CDK7_CDK7_ST	P04637	TP53	P50613	CDK7	S315	P322R	322	Missense	distal	7	no	14.594	13.516	EPSD	COSMIC	13.598	Loss
CMGC_CDK_CDK7_CDK7_ST	P04637	TP53	P50613	CDK7	S315	N311K	311	Missense	distal	-4	no	14.594	14.861	EPSD	COSMIC	13.598	Up-regulation
CMGC_CDK_CDK7_CDK7_ST	P04637	TP53	P50613	CDK7	S315	Q317K	317	Missense	proximal	2	no	14.594	16.540	EPSD	COSMIC	13.598	Up-regulation
CMGC_CDK_CDK7_CDK7_ST	P04637	TP53	P50613	CDK7	S315	S315P	315	Missense	central	0	yes	14.594	0.000	EPSD	COSMIC	13.598	Loss
CMGC_CDK_CDK7_CDK7_ST	P04637	TP53	P50613	CDK7	S315	N310H	310	Missense	distal	-5	no	14.594	13.880	EPSD	COSMIC	13.598	Down-regulation
CMGC_CDK_CDK7_CDK7_ST	P04637	TP53	P50613	CDK7	S315	S314C	314	Missense	proximal	-1	no	14.594	14.245	EPSD	COSMIC	13.598	Down-regulation
CMGC_CDK_CDK7_CDK7_ST	P04637	TP53	P50613	CDK7	S315	P318A	318	Missense	distal	3	no	14.594	13.600	EPSD	COSMIC	13.598	Down-regulation
CMGC_CDK_CDK7_CDK7_ST	P04637	TP53	P50613	CDK7	S315	P316L	316	Missense	proximal	1	no	14.594	7.123	EPSD	COSMIC	13.598	Loss
CMGC_CDK_CDK7_CDK7_ST	P04637	TP53	P50613	CDK7	S315	L308M	308	Missense	distal	-7	no	14.594	12.070	EPSD	COSMIC	13.598	Loss
CMGC_CDK_CDK7_CDK7_ST	P04637	TP53	P50613	CDK7	S315	S313C	313	Missense	proximal	-2	no	14.594	13.975	EPSD	COSMIC	13.598	Down-regulation
CMGC_CDK_CDK7_CDK7_ST	P04637	TP53	P50613	CDK7	S315	N311H	311	Missense	distal	-4	no	14.594	14.746	EPSD	COSMIC	13.598	Up-regulation
CMGC_CDK_CDK7_CDK7_ST	P04637	TP53	P50613	CDK7	S315	L308V	308	Missense	distal	-7	no	14.594	12.622	EPSD	COSMIC	13.598	Loss
CMGC_CDK_CDK7_CDK7_ST	P04637	TP53	P50613	CDK7	S315	S314F	314	Missense	proximal	-1	no	14.594	13.986	EPSD	COSMIC	13.598	Down-regulation
CMGC_CDK_CDK7_CDK7_ST	P04637	TP53	P50613	CDK7	S315	K319R	319	Missense	distal	4	no	14.594	16.107	EPSD	COSMIC	13.598	Up-regulation
CMGC_CDK_CDK7_CDK7_ST	P04637	TP53	P50613	CDK7	S315	T312A	312	Missense	distal	-3	no	14.594	16.361	EPSD	COSMIC	13.598	Up-regulation
CMGC_CDK_CDK7_CDK7_ST	P04637	TP53	P50613	CDK7	S315	N310D	310	Missense	distal	-5	no	14.594	15.456	EPSD	COSMIC	13.598	Up-regulation
CMGC_CDK_CDK7_CDK7_ST	P04637	TP53	P50613	CDK7	S315	N311D	311	Missense	distal	-4	no	14.594	14.716	EPSD	COSMIC	13.598	Up-regulation
CMGC_CDK_CDK7_CDK7_ST	P04637	TP53	P50613	CDK7	S315	P309R	309	Missense	distal	-6	no	14.594	14.541	EPSD	COSMIC	13.598	Down-regulation
CMGC_CDK_CDK7_CDK7_ST	P04637	TP53	P50613	CDK7	S315	S313N	313	Missense	proximal	-2	no	14.594	14.266	EPSD	COSMIC	13.598	Down-regulation
CMGC_CDK_CDK7_CDK7_ST	P04637	TP53	P50613	CDK7	S315	Q317P	317	Missense	proximal	2	no	14.594	15.311	EPSD	COSMIC	13.598	Up-regulation
CMGC_CDK_CDK7_CDK7_ST	P04637	TP53	P50613	CDK7	S315	P316S	316	Missense	proximal	1	no	14.594	6.061	EPSD	COSMIC	13.598	Loss
CMGC_CDK_CDK7_CDK7_ST	P04637	TP53	P50613	CDK7	S371	S367F	367	Missense	distal	-4	no	20.263	21.035	PhosphoSitePlus;EPSD	COSMIC	13.598	Up-regulation
CMGC_CDK_CDK7_CDK7_ST	P04637	TP53	P50613	CDK7	S371	K370N	370	Missense	proximal	-1	no	20.263	20.743	PhosphoSitePlus;EPSD	COSMIC	13.598	Up-regulation
CMGC_CDK_CDK7_CDK7_ST	P04637	TP53	P50613	CDK7	S371	A364D	364	Missense	distal	-7	no	20.263	21.775	PhosphoSitePlus;EPSD	COSMIC	13.598	Up-regulation
CMGC_CDK_CDK7_CDK7_ST	P04637	TP53	P50613	CDK7	S371	H365Y	365	Missense	distal	-6	no	20.263	20.910	PhosphoSitePlus;EPSD	COSMIC	13.598	Up-regulation
CMGC_CDK_CDK7_CDK7_ST	P04637	TP53	P50613	CDK7	S371	A364T	364	Missense	distal	-7	no	20.263	22.081	PhosphoSitePlus;EPSD	COSMIC	13.598	Up-regulation
CMGC_CDK_CDK7_CDK7_ST	P04637	TP53	P50613	CDK7	S371	S376T	376	Missense	distal	5	no	20.263	18.043	PhosphoSitePlus;EPSD	COSMIC	13.598	Down-regulation
CMGC_CDK_CDK7_CDK7_ST	P04637	TP53	P50613	CDK7	S371	S366A	366	Missense	distal	-5	no	20.263	18.208	PhosphoSitePlus;EPSD	COSMIC	13.598	Down-regulation
CMGC_CDK_CDK7_CDK7_ST	P04637	TP53	P50613	CDK7	S371	T377I	377	Missense	distal	6	no	20.263	20.215	PhosphoSitePlus;EPSD	COSMIC	13.598	Down-regulation
CMGC_CDK_CDK7_CDK7_ST	P04637	TP53	P50613	CDK7	S371	S378F	378	Missense	distal	7	no	20.263	25.085	PhosphoSitePlus;EPSD	COSMIC	13.598	Up-regulation
CMGC_CDK_CDK7_CDK7_ST	P04637	TP53	P50613	CDK7	S371	K370Q	370	Missense	proximal	-1	no	20.263	20.715	PhosphoSitePlus;EPSD	COSMIC	13.598	Up-regulation
CMGC_CDK_CDK7_CDK7_ST	P04637	TP53	P50613	CDK7	S371	K373R	373	Missense	proximal	2	no	20.263	20.328	PhosphoSitePlus;EPSD	COSMIC	13.598	Up-regulation
CMGC_CDK_CDK7_CDK7_ST	P04637	TP53	P50613	CDK7	S371	S376F	376	Missense	distal	5	no	20.263	18.059	PhosphoSitePlus;EPSD	COSMIC	13.598	Down-regulation
CMGC_CDK_CDK7_CDK7_ST	P04637	TP53	P50613	CDK7	S371	G374S	374	Missense	distal	3	no	20.263	20.313	PhosphoSitePlus;EPSD	COSMIC	13.598	Up-regulation
CMGC_CDK_CDK7_CDK7_ST	P04637	TP53	P50613	CDK7	S371	S376A	376	Missense	distal	5	no	20.263	19.621	PhosphoSitePlus;EPSD	COSMIC	13.598	Down-regulation
CMGC_CDK_CDK7_CDK7_ST	P04637	TP53	P50613	CDK7	S371	S371P	371	Missense	central	0	yes	20.263	0.000	PhosphoSitePlus;EPSD	COSMIC	13.598	Loss
CMGC_CDK_CDK7_CDK7_ST	P04637	TP53	P50613	CDK7	S376	K370N	370	Missense	distal	-6	no	20.595	20.401	EPSD;PhosphoSitePlus	COSMIC	13.598	Down-regulation
CMGC_CDK_CDK7_CDK7_ST	P04637	TP53	P50613	CDK7	S376	L383F	383	Missense	distal	7	no	20.595	25.162	EPSD;PhosphoSitePlus	COSMIC	13.598	Up-regulation
CMGC_CDK_CDK7_CDK7_ST	P04637	TP53	P50613	CDK7	S376	R379H	379	Missense	distal	3	no	20.595	19.754	EPSD;PhosphoSitePlus	COSMIC	13.598	Down-regulation
CMGC_CDK_CDK7_CDK7_ST	P04637	TP53	P50613	CDK7	S376	H380Y	380	Missense	distal	4	no	20.595	21.315	EPSD;PhosphoSitePlus	COSMIC	13.598	Up-regulation
CMGC_CDK_CDK7_CDK7_ST	P04637	TP53	P50613	CDK7	S376	T377I	377	Missense	proximal	1	no	20.595	21.175	EPSD;PhosphoSitePlus	COSMIC	13.598	Up-regulation
CMGC_CDK_CDK7_CDK7_ST	P04637	TP53	P50613	CDK7	S376	S378F	378	Missense	proximal	2	no	20.595	22.256	EPSD;PhosphoSitePlus	COSMIC	13.598	Up-regulation
CMGC_CDK_CDK7_CDK7_ST	P04637	TP53	P50613	CDK7	S376	K370Q	370	Missense	distal	-6	no	20.595	20.497	EPSD;PhosphoSitePlus	COSMIC	13.598	Down-regulation
CMGC_CDK_CDK7_CDK7_ST	P04637	TP53	P50613	CDK7	S376	K381N	381	Missense	distal	5	no	20.595	21.052	EPSD;PhosphoSitePlus	COSMIC	13.598	Up-regulation
CMGC_CDK_CDK7_CDK7_ST	P04637	TP53	P50613	CDK7	S376	R379P	379	Missense	distal	3	no	20.595	20.641	EPSD;PhosphoSitePlus	COSMIC	13.598	Up-regulation
CMGC_CDK_CDK7_CDK7_ST	P04637	TP53	P50613	CDK7	S376	K373R	373	Missense	distal	-3	no	20.595	23.900	EPSD;PhosphoSitePlus	COSMIC	13.598	Up-regulation
CMGC_CDK_CDK7_CDK7_ST	P04637	TP53	P50613	CDK7	S376	S376F	376	Missense	central	0	yes	20.595	0.000	EPSD;PhosphoSitePlus	COSMIC	13.598	Loss
CMGC_CDK_CDK7_CDK7_ST	P04637	TP53	P50613	CDK7	S376	G374S	374	Missense	proximal	-2	no	20.595	20.996	EPSD;PhosphoSitePlus	COSMIC	13.598	Up-regulation
CMGC_CDK_CDK7_CDK7_ST	P04637	TP53	P50613	CDK7	S376	S376A	376	Missense	central	0	yes	20.595	0.000	EPSD;PhosphoSitePlus	COSMIC	13.598	Loss
CMGC_CDK_CDK7_CDK7_ST	P04637	TP53	P50613	CDK7	S376	S371P	371	Missense	distal	-5	no	20.595	20.442	EPSD;PhosphoSitePlus	COSMIC	13.598	Down-regulation
CMGC_CDK_CDK7_CDK7_ST	P04637	TP53	P50613	CDK7	S378	L383F	383	Missense	distal	5	no	19.642	18.407	EPSD;PhosphoSitePlus	COSMIC	13.598	Down-regulation
CMGC_CDK_CDK7_CDK7_ST	P04637	TP53	P50613	CDK7	S378	R379H	379	Missense	proximal	1	no	19.642	17.783	EPSD;PhosphoSitePlus	COSMIC	13.598	Down-regulation
CMGC_CDK_CDK7_CDK7_ST	P04637	TP53	P50613	CDK7	S378	S376T	376	Missense	proximal	-2	no	19.642	19.150	EPSD;PhosphoSitePlus	COSMIC	13.598	Down-regulation
CMGC_CDK_CDK7_CDK7_ST	P04637	TP53	P50613	CDK7	S378	H380Y	380	Missense	proximal	2	no	19.642	19.028	EPSD;PhosphoSitePlus	COSMIC	13.598	Down-regulation
CMGC_CDK_CDK7_CDK7_ST	P04637	TP53	P50613	CDK7	S378	T377I	377	Missense	proximal	-1	no	19.642	19.663	EPSD;PhosphoSitePlus	COSMIC	13.598	Up-regulation
CMGC_CDK_CDK7_CDK7_ST	P04637	TP53	P50613	CDK7	S378	S378F	378	Missense	central	0	yes	19.642	0.000	EPSD;PhosphoSitePlus	COSMIC	13.598	Loss
CMGC_CDK_CDK7_CDK7_ST	P04637	TP53	P50613	CDK7	S378	K381N	381	Missense	distal	3	no	19.642	19.535	EPSD;PhosphoSitePlus	COSMIC	13.598	Down-regulation
CMGC_CDK_CDK7_CDK7_ST	P04637	TP53	P50613	CDK7	S378	R379P	379	Missense	proximal	1	no	19.642	29.221	EPSD;PhosphoSitePlus	COSMIC	13.598	Up-regulation
CMGC_CDK_CDK7_CDK7_ST	P04637	TP53	P50613	CDK7	S378	M384I	384	Missense	distal	6	no	19.642	18.413	EPSD;PhosphoSitePlus	COSMIC	13.598	Down-regulation
CMGC_CDK_CDK7_CDK7_ST	P04637	TP53	P50613	CDK7	S378	K373R	373	Missense	distal	-5	no	19.642	19.615	EPSD;PhosphoSitePlus	COSMIC	13.598	Down-regulation
CMGC_CDK_CDK7_CDK7_ST	P04637	TP53	P50613	CDK7	S378	S376F	376	Missense	proximal	-2	no	19.642	19.040	EPSD;PhosphoSitePlus	COSMIC	13.598	Down-regulation
CMGC_CDK_CDK7_CDK7_ST	P04637	TP53	P50613	CDK7	S378	G374S	374	Missense	distal	-4	no	19.642	18.729	EPSD;PhosphoSitePlus	COSMIC	13.598	Down-regulation
CMGC_CDK_CDK7_CDK7_ST	P04637	TP53	P50613	CDK7	S378	S376A	376	Missense	proximal	-2	no	19.642	19.444	EPSD;PhosphoSitePlus	COSMIC	13.598	Down-regulation
CMGC_CDK_CDK7_CDK7_ST	P04637	TP53	P50613	CDK7	S378	S371P	371	Missense	distal	-7	no	19.642	21.719	EPSD;PhosphoSitePlus	COSMIC	13.598	Up-regulation
CMGC_CDK_CDK7_CDK7_ST	P04637	TP53	P50613	CDK7	S392	G389E	389	Missense	distal	-3	no	11.549	15.814	EPSD;PhosphoSitePlus	COSMIC	13.598	Gain
CMGC_CDK_CDK7_CDK7_ST	O00267	SUPT5H	P50613	CDK7	S195	F200L	200	Missense	distal	5	no	16.092	17.327	EPSD	COSMIC	13.598	Up-regulation
CMGC_CDK_CDK7_CDK7_ST	O00267	SUPT5H	P50613	CDK7	S195	S195F	195	Missense	central	0	yes	16.092	0.000	EPSD	COSMIC	13.598	Loss
CMGC_CDK_CDK7_CDK7_ST	O00267	SUPT5H	P50613	CDK7	S195	T192M	192	Missense	distal	-3	no	16.092	16.742	EPSD	COSMIC	13.598	Up-regulation
CMGC_CDK_CDK7_CDK7_ST	O00267	SUPT5H	P50613	CDK7	S195	R190Q	190	Missense	distal	-5	no	16.092	16.014	EPSD	COSMIC	13.598	Down-regulation
CMGC_CDK_CDK7_CDK7_ST	O00267	SUPT5H	P50613	CDK7	S195	R198C	198	Missense	distal	3	no	16.092	15.885	EPSD	COSMIC	13.598	Down-regulation
CMGC_CDK_CDK7_CDK7_ST	O00267	SUPT5H	P50613	CDK7	S686	R681H	681	Missense	distal	-5	no	14.289	12.219	EPSD	COSMIC	13.598	Loss
CMGC_CDK_CDK7_CDK7_ST	O00267	SUPT5H	P50613	CDK7	S738	T739P	739	Missense	proximal	1	no	12.405	19.566	EPSD	COSMIC	13.598	Gain
CMGC_CDK_CDK7_CDK7_ST	O00267	SUPT5H	P50613	CDK7	S812	G819W	819	Missense	distal	7	no	14.513	15.664	EPSD	COSMIC	13.598	Up-regulation
CMGC_CDK_CDK7_CDK7_ST	O00267	SUPT5H	P50613	CDK7	S812	A816V	816	Missense	distal	4	no	14.513	14.075	EPSD	COSMIC	13.598	Down-regulation
CMGC_CDK_CDK7_CDK7_ST	O00267	SUPT5H	P50613	CDK7	S812	S818G	818	Missense	distal	6	no	14.513	13.625	EPSD	COSMIC	13.598	Down-regulation
CMGC_CDK_CDK7_CDK7_ST	O00267	SUPT5H	P50613	CDK7	T814	G819W	819	Missense	distal	5	no	14.065	11.163	EPSD	COSMIC	13.598	Loss
CMGC_CDK_CDK7_CDK7_ST	O00267	SUPT5H	P50613	CDK7	T814	A816V	816	Missense	proximal	2	no	14.065	15.165	EPSD	COSMIC	13.598	Up-regulation
CMGC_CDK_CDK7_CDK7_ST	O00267	SUPT5H	P50613	CDK7	T814	S818G	818	Missense	distal	4	no	14.065	14.268	EPSD	COSMIC	13.598	Up-regulation
CMGC_CDK_CDK7_CDK7_ST	O00267	SUPT5H	P50613	CDK7	T828	E834K	834	Missense	distal	6	no	20.944	20.070	EPSD	COSMIC	13.598	Down-regulation
CMGC_CDK_CDK7_CDK7_ST	O00267	SUPT5H	P50613	CDK7	T845	D841N	841	Missense	distal	-4	no	16.628	16.507	EPSD	COSMIC	13.598	Down-regulation
CMGC_CDK_CDK7_CDK7_ST	O00267	SUPT5H	P50613	CDK7	T845	P848L	848	Missense	distal	3	no	16.628	15.620	EPSD	COSMIC	13.598	Down-regulation
CMGC_CDK_CDK7_CDK7_ST	O00267	SUPT5H	P50613	CDK7	T845	P844L	844	Missense	proximal	-1	no	16.628	16.601	EPSD	COSMIC	13.598	Down-regulation
CMGC_CDK_CDK7_CDK7_ST	O00267	SUPT5H	P50613	CDK7	T854	P857S	857	Missense	distal	3	no	26.610	25.862	EPSD	COSMIC	13.598	Down-regulation
CMGC_CDK_CDK7_CDK7_ST	O00267	SUPT5H	P50613	CDK7	T854	P857L	857	Missense	distal	3	no	26.610	25.601	EPSD	COSMIC	13.598	Down-regulation
CMGC_CDK_CDK7_CDK7_ST	O00267	SUPT5H	P50613	CDK7	T854	P848L	848	Missense	distal	-6	no	26.610	26.588	EPSD	COSMIC	13.598	Down-regulation
CMGC_CDK_CDK7_CDK7_ST	O00267	SUPT5H	P50613	CDK7	S867	D864H	864	Missense	distal	-3	no	20.493	22.019	EPSD	COSMIC	13.598	Up-regulation
CMGC_CDK_CDK7_CDK7_ST	O00267	SUPT5H	P50613	CDK7	S867	P872A	872	Missense	distal	5	no	20.493	21.236	EPSD	COSMIC	13.598	Up-regulation
CMGC_CDK_CDK7_CDK7_ST	O00267	SUPT5H	P50613	CDK7	S867	S866L	866	Missense	proximal	-1	no	20.493	20.212	EPSD	COSMIC	13.598	Down-regulation
CMGC_CDK_CDK7_CDK7_ST	O00267	SUPT5H	P50613	CDK7	S867	P868A	868	Missense	proximal	1	no	20.493	1.740	EPSD	COSMIC	13.598	Loss
CMGC_CDK_CDK7_CDK7_ST	O00267	SUPT5H	P50613	CDK7	S897	P892S	892	Missense	distal	-5	no	15.862	16.015	EPSD	COSMIC	13.598	Up-regulation
CMGC_CDK_CDK7_CDK7_ST	O00267	SUPT5H	P50613	CDK7	S951	P958L	958	Missense	distal	7	no	15.110	10.438	EPSD	COSMIC	13.598	Loss
CMGC_CDK_CDK7_CDK7_ST	O00267	SUPT5H	P50613	CDK7	S951	P958S	958	Missense	distal	7	no	15.110	10.183	EPSD	COSMIC	13.598	Loss
CMGC_CDK_CDK7_CDK7_ST	O00267	SUPT5H	P50613	CDK7	S951	P945L	945	Missense	distal	-6	no	15.110	15.089	EPSD	COSMIC	13.598	Down-regulation
CMGC_CDK_CDK7_CDK7_ST	P50750	CDK9	P50613	CDK7	S175	R172W	172	Missense	distal	-3	no	21.983	15.994	PhosphoSitePlus	COSMIC	13.598	Down-regulation
CMGC_CDK_CDK7_CDK7_ST	P50750	CDK9	P50613	CDK7	S180	R184C	184	Missense	distal	4	no	14.463	14.429	EPSD	COSMIC;GDSC;CCLE	13.598	Down-regulation
CMGC_CDK_CDK7_CDK7_ST	P50750	CDK9	P50613	CDK7	T186	R184C	184	Missense	proximal	-2	no	18.718	18.630	EPSD	COSMIC;GDSC;CCLE	13.598	Down-regulation
CMGC_CDK_CDK7_CDK7_ST	P50750	CDK9	P50613	CDK7	T330	H331Y	331	Missense	proximal	1	no	14.167	15.453	EPSD	COSMIC	13.598	Up-regulation
CMGC_CDK_CDK7_CDK7_ST	P50750	CDK9	P50613	CDK7	T330	D323N	323	Missense	distal	-7	no	14.167	14.201	EPSD	COSMIC;GDSC;CCLE	13.598	Up-regulation
CMGC_CDK_CDK7_CDK7_ST	P50750	CDK9	P50613	CDK7	T330	T333M	333	Missense	distal	3	no	14.167	13.825	EPSD	COSMIC	13.598	Down-regulation
CMGC_CDK_CDK7_CDK7_ST	P50750	CDK9	P50613	CDK7	T362	A361T	361	Missense	proximal	-1	no	15.027	14.840	EPSD	COSMIC;GDSC;CCLE	13.598	Down-regulation
CMGC_CDK_CDK7_CDK7_ST	P24928	POLR2A	P50613	CDK7	S217	E219V	219	Missense	proximal	2	no	15.595	16.519	EPSD	COSMIC	13.598	Up-regulation
CMGC_CDK_CDK7_CDK7_ST	P10276	RARA	P50613	CDK7	S74	P73S	73	Missense	proximal	-1	no	15.000	15.253	EPSD	COSMIC	13.598	Up-regulation
CMGC_CDK_CDK7_CDK7_ST	P10276	RARA	P50613	CDK7	S77	R83H	83	Missense	distal	6	no	23.434	22.761	PhosphoSitePlus	COSMIC;GDSC;CCLE	13.598	Down-regulation
CMGC_CDK_CDK7_CDK7_ST	P10276	RARA	P50613	CDK7	S77	R83C	83	Missense	distal	6	no	23.434	22.237	PhosphoSitePlus	COSMIC	13.598	Down-regulation
CMGC_CDK_CDK7_CDK7_ST	P10276	RARA	P50613	CDK7	S77	P73S	73	Missense	distal	-4	no	23.434	23.240	PhosphoSitePlus	COSMIC	13.598	Down-regulation
CMGC_CDK_CDK7_CDK7_ST	P10276	RARA	P50613	CDK7	S219	E215G	215	Missense	distal	-4	no	13.510	14.418	EPSD	COSMIC	13.598	Gain
CMGC_CDK_CDK7_CDK7_ST	P10276	RARA	P50613	CDK7	S445	P450F	450	Missense	distal	5	no	15.328	14.509	EPSD	COSMIC	13.598	Down-regulation
CMGC_CDK_CDK7_CDK7_ST	P10276	RARA	P50613	CDK7	S445	P439S	439	Missense	distal	-6	no	15.328	15.727	EPSD	COSMIC;CCLE	13.598	Up-regulation
CMGC_CDK_CDK7_CDK7_ST	P10276	RARA	P50613	CDK7	S445	G442C	442	Missense	distal	-3	no	15.328	16.335	EPSD	COSMIC	13.598	Up-regulation
CMGC_CDK_CDK7_CDK7_ST	P10276	RARA	P50613	CDK7	S445	A438P	438	Missense	distal	-7	no	15.328	17.743	EPSD	COSMIC	13.598	Up-regulation
CMGC_CDK_CDK7_CDK7_ST	P10276	RARA	P50613	CDK7	S445	P439L	439	Missense	distal	-6	no	15.328	15.307	EPSD	COSMIC	13.598	Down-regulation
CMGC_CDK_CDK7_CDK7_ST	P10276	RARA	P50613	CDK7	S445	S452F	452	Missense	distal	7	no	15.328	20.150	EPSD	COSMIC	13.598	Up-regulation
CMGC_CDK_CDK7_CDK7_ST	P10276	RARA	P50613	CDK7	S445	S447F	447	Missense	proximal	2	no	15.328	16.989	EPSD	COSMIC	13.598	Up-regulation
CMGC_CDK_CDK7_CDK7_ST	P10276	RARA	P50613	CDK7	S445	S451R	451	Missense	distal	6	no	15.328	16.640	EPSD	COSMIC	13.598	Up-regulation
CMGC_CDK_CDK7_CDK7_ST	P10276	RARA	P50613	CDK7	S449	P450F	450	Missense	proximal	1	no	16.011	10.126	EPSD	COSMIC	13.598	Loss
CMGC_CDK_CDK7_CDK7_ST	P10276	RARA	P50613	CDK7	S449	G442C	442	Missense	distal	-7	no	16.011	14.677	EPSD	COSMIC	13.598	Down-regulation
CMGC_CDK_CDK7_CDK7_ST	P10276	RARA	P50613	CDK7	S449	R454K	454	Missense	distal	5	no	16.011	17.361	EPSD	COSMIC	13.598	Up-regulation
CMGC_CDK_CDK7_CDK7_ST	P10276	RARA	P50613	CDK7	S449	S452F	452	Missense	distal	3	no	16.011	16.666	EPSD	COSMIC	13.598	Up-regulation
CMGC_CDK_CDK7_CDK7_ST	P10276	RARA	P50613	CDK7	S449	S456R	456	Missense	distal	7	no	16.011	19.860	EPSD	COSMIC;CCLE	13.598	Up-regulation
CMGC_CDK_CDK7_CDK7_ST	P10276	RARA	P50613	CDK7	S449	S447F	447	Missense	proximal	-2	no	16.011	15.409	EPSD	COSMIC	13.598	Down-regulation
CMGC_CDK_CDK7_CDK7_ST	P10276	RARA	P50613	CDK7	S449	S451R	451	Missense	proximal	2	no	16.011	17.802	EPSD	COSMIC	13.598	Up-regulation
CMGC_CDK_CDK7_CDK7_ST	P10276	RARA	P50613	CDK7	S449	S456C	456	Missense	distal	7	no	16.011	18.674	EPSD	COSMIC	13.598	Up-regulation
CMGC_CDK_CDK7_CDK7_ST	P10276	RARA	P50613	CDK7	S451	P450F	450	Missense	proximal	-1	no	20.702	20.347	EPSD	COSMIC	13.598	Down-regulation
CMGC_CDK_CDK7_CDK7_ST	P10276	RARA	P50613	CDK7	S451	R454K	454	Missense	distal	3	no	20.702	20.416	EPSD	COSMIC	13.598	Down-regulation
CMGC_CDK_CDK7_CDK7_ST	P10276	RARA	P50613	CDK7	S451	P457L	457	Missense	distal	6	no	20.702	21.148	EPSD	COSMIC	13.598	Up-regulation
CMGC_CDK_CDK7_CDK7_ST	P10276	RARA	P50613	CDK7	S451	S452F	452	Missense	proximal	1	no	20.702	23.349	EPSD	COSMIC	13.598	Up-regulation
CMGC_CDK_CDK7_CDK7_ST	P10276	RARA	P50613	CDK7	S451	A458S	458	Missense	distal	7	no	20.702	16.988	EPSD	COSMIC;CCLE	13.598	Down-regulation
CMGC_CDK_CDK7_CDK7_ST	P10276	RARA	P50613	CDK7	S451	S456R	456	Missense	distal	5	no	20.702	17.655	EPSD	COSMIC;CCLE	13.598	Down-regulation
CMGC_CDK_CDK7_CDK7_ST	P10276	RARA	P50613	CDK7	S451	S447F	447	Missense	distal	-4	no	20.702	21.474	EPSD	COSMIC	13.598	Up-regulation
CMGC_CDK_CDK7_CDK7_ST	P10276	RARA	P50613	CDK7	S451	S451R	451	Missense	central	0	yes	20.702	0.000	EPSD	COSMIC	13.598	Loss
CMGC_CDK_CDK7_CDK7_ST	P10276	RARA	P50613	CDK7	S451	P457S	457	Missense	distal	6	no	20.702	20.335	EPSD	COSMIC	13.598	Down-regulation
CMGC_CDK_CDK7_CDK7_ST	P10276	RARA	P50613	CDK7	S451	S456C	456	Missense	distal	5	no	20.702	19.225	EPSD	COSMIC	13.598	Down-regulation
CMGC_CDK_CDK7_CDK7_ST	P10276	RARA	P50613	CDK7	S461	S461C	461	Missense	central	0	yes	18.369	0.000	EPSD	COSMIC	13.598	Loss
CMGC_CDK_CDK7_CDK7_ST	P10276	RARA	P50613	CDK7	S461	R454K	454	Missense	distal	-7	no	18.369	19.997	EPSD	COSMIC	13.598	Up-regulation
CMGC_CDK_CDK7_CDK7_ST	P10276	RARA	P50613	CDK7	S461	P457L	457	Missense	distal	-4	no	18.369	18.402	EPSD	COSMIC	13.598	Up-regulation
CMGC_CDK_CDK7_CDK7_ST	P10276	RARA	P50613	CDK7	S461	A458S	458	Missense	distal	-3	no	18.369	16.418	EPSD	COSMIC;CCLE	13.598	Down-regulation
CMGC_CDK_CDK7_CDK7_ST	P10276	RARA	P50613	CDK7	S461	S456R	456	Missense	distal	-5	no	18.369	16.867	EPSD	COSMIC;CCLE	13.598	Down-regulation
CMGC_CDK_CDK7_CDK7_ST	P10276	RARA	P50613	CDK7	S461	P457S	457	Missense	distal	-4	no	18.369	18.175	EPSD	COSMIC	13.598	Down-regulation
CMGC_CDK_CDK7_CDK7_ST	P10276	RARA	P50613	CDK7	S461	S456C	456	Missense	distal	-5	no	18.369	16.712	EPSD	COSMIC	13.598	Down-regulation
CMGC_CDK_CDK7_CDK7_ST	Q9H0D6	XRN2	P50613	CDK7	S16	V22M	22	Missense	distal	6	no	20.912	22.289	EPSD	COSMIC;CCLE	13.598	Up-regulation
CMGC_CDK_CDK7_CDK7_ST	Q9H0D6	XRN2	P50613	CDK7	T439	A442T	442	Missense	distal	3	no	25.194	25.969	PhosphoSitePlus	COSMIC;GDSC;CCLE	13.598	Up-regulation
CMGC_CDK_CDK7_CDK7_ST	Q9H0D6	XRN2	P50613	CDK7	T439	R446S	446	Missense	distal	7	no	25.194	21.345	PhosphoSitePlus	COSMIC	13.598	Down-regulation
CMGC_CDK_CDK7_CDK7_ST	Q9H0D6	XRN2	P50613	CDK7	S448	A442T	442	Missense	distal	-6	no	20.679	20.693	EPSD	COSMIC;GDSC;CCLE	13.598	Up-regulation
CMGC_CDK_CDK7_CDK7_ST	Q9H0D6	XRN2	P50613	CDK7	S448	R446S	446	Missense	proximal	-2	no	20.679	21.211	EPSD	COSMIC	13.598	Up-regulation
CMGC_CDK_CDK7_CDK7_ST	Q9H0D6	XRN2	P50613	CDK7	S475	S473L	473	Missense	proximal	-2	no	15.716	15.611	EPSD	COSMIC	13.598	Down-regulation
CMGC_CDK_CDK7_CDK7_ST	Q9H0D6	XRN2	P50613	CDK7	S475	T478P	478	Missense	distal	3	no	15.716	15.935	EPSD	COSMIC	13.598	Up-regulation
CMGC_CDK_CDK7_CDK7_ST	Q9H0D6	XRN2	P50613	CDK7	S475	S479T	479	Missense	distal	4	no	15.716	16.101	EPSD	COSMIC	13.598	Up-regulation
CMGC_CDK_CDK7_CDK7_ST	Q9H0D6	XRN2	P50613	CDK7	S475	S470Y	470	Missense	distal	-5	no	15.716	13.674	EPSD	COSMIC	13.598	Down-regulation
CMGC_CDK_CDK7_CDK7_ST	Q9H0D6	XRN2	P50613	CDK7	S475	S479R	479	Missense	distal	4	no	15.716	18.317	EPSD	COSMIC	13.598	Up-regulation
CMGC_CDK_CDK7_CDK7_ST	Q9H0D6	XRN2	P50613	CDK7	S485	P486L	486	Missense	proximal	1	no	16.627	9.157	EPSD	COSMIC	13.598	Loss
CMGC_CDK_CDK7_CDK7_ST	Q9H0D6	XRN2	P50613	CDK7	S485	T478P	478	Missense	distal	-7	no	16.627	17.224	EPSD	COSMIC	13.598	Up-regulation
CMGC_CDK_CDK7_CDK7_ST	Q9H0D6	XRN2	P50613	CDK7	S485	S479T	479	Missense	distal	-6	no	16.627	16.199	EPSD	COSMIC	13.598	Down-regulation
CMGC_CDK_CDK7_CDK7_ST	Q9H0D6	XRN2	P50613	CDK7	S485	S479R	479	Missense	distal	-6	no	16.627	16.175	EPSD	COSMIC	13.598	Down-regulation
CMGC_CDK_CDK7_CDK7_ST	Q01094	E2F1	P50613	CDK7	T96	A102T	102	Missense	distal	6	no	18.866	17.156	EPSD	COSMIC	13.598	Down-regulation
CMGC_CDK_CDK7_CDK7_ST	Q01094	E2F1	P50613	CDK7	T311	S318F	318	Missense	distal	7	no	10.525	15.346	EPSD	COSMIC	13.598	Gain
CMGC_CDK_CDK7_CDK7_ST	Q01094	E2F1	P50613	CDK7	S313	S318F	318	Missense	distal	5	no	13.787	11.583	EPSD	COSMIC	13.598	Loss
CMGC_CDK_CDK7_CDK7_ST	Q01094	E2F1	P50613	CDK7	S313	P312L	312	Missense	proximal	-1	no	13.787	13.759	EPSD	COSMIC	13.598	Down-regulation
CMGC_CDK_CDK7_CDK7_ST	Q01094	E2F1	P50613	CDK7	S332	S336L	336	Missense	distal	4	no	15.582	16.159	EPSD	COSMIC	13.598	Up-regulation
CMGC_CDK_CDK7_CDK7_ST	Q01094	E2F1	P50613	CDK7	S332	I330T	330	Missense	proximal	-2	no	15.582	15.317	EPSD	COSMIC	13.598	Down-regulation
CMGC_CDK_CDK7_CDK7_ST	Q01094	E2F1	P50613	CDK7	S332	P335Q	335	Missense	distal	3	no	15.582	15.699	EPSD	COSMIC;GDSC;CCLE	13.598	Up-regulation
CMGC_CDK_CDK7_CDK7_ST	Q01094	E2F1	P50613	CDK7	S332	P335S	335	Missense	distal	3	no	15.582	14.835	EPSD	COSMIC	13.598	Down-regulation
CMGC_CDK_CDK7_CDK7_ST	Q01094	E2F1	P50613	CDK7	S332	P334L	334	Missense	proximal	2	no	15.582	15.167	EPSD	COSMIC	13.598	Down-regulation
CMGC_CDK_CDK7_CDK7_ST	Q01094	E2F1	P50613	CDK7	T344	S341F	341	Missense	distal	-3	no	14.121	13.091	EPSD	COSMIC	13.598	Loss
CMGC_CDK_CDK7_CDK7_ST	Q01094	E2F1	P50613	CDK7	T344	P346S	346	Missense	proximal	2	no	14.121	13.624	EPSD	COSMIC;GDSC	13.598	Down-regulation
CMGC_CDK_CDK7_CDK7_ST	Q01094	E2F1	P50613	CDK7	T344	L350V	350	Missense	distal	6	no	14.121	13.081	EPSD	COSMIC	13.598	Loss
CMGC_CDK_CDK7_CDK7_ST	Q01094	E2F1	P50613	CDK7	S364	R366Q	366	Missense	proximal	2	no	15.270	13.259	EPSD	COSMIC	13.598	Loss
CMGC_CDK_CDK7_CDK7_ST	Q01094	E2F1	P50613	CDK7	S403	P404S	404	Missense	proximal	1	no	24.807	16.273	EPSD;PhosphoSitePlus	COSMIC	13.598	Down-regulation
CMGC_CDK_CDK7_CDK7_ST	P11802	CDK4	P50613	CDK7	T172	V174M	174	Missense	proximal	2	no	38.520	38.104	PhosphoSitePlus	COSMIC	13.598	Down-regulation
CMGC_CDK_CDK7_CDK7_ST	P11802	CDK4	P50613	CDK7	T172	Q168E	168	Missense	distal	-4	no	38.520	38.411	PhosphoSitePlus	COSMIC	13.598	Down-regulation
CMGC_CDK_CDK7_CDK7_ST	P11802	CDK4	P50613	CDK7	T172	V174G	174	Missense	proximal	2	no	38.520	38.327	PhosphoSitePlus	COSMIC	13.598	Down-regulation
CMGC_CDK_CDK7_CDK7_ST	P11802	CDK4	P50613	CDK7	T172	T172R	172	Missense	central	0	yes	38.520	0.000	PhosphoSitePlus	COSMIC	13.598	Loss
CMGC_CDK_CDK7_CDK7_ST	P11802	CDK4	P50613	CDK7	T172	V175F	175	Missense	distal	3	no	38.520	39.287	PhosphoSitePlus	COSMIC	13.598	Up-regulation
CMGC_CDK_CDK7_CDK7_ST	P11802	CDK4	P50613	CDK7	S243	R246H	246	Missense	distal	3	no	15.913	15.071	EPSD	COSMIC	13.598	Down-regulation
CMGC_CDK_CDK7_CDK7_ST	P11802	CDK4	P50613	CDK7	S243	G247E	247	Missense	distal	4	no	15.913	16.137	EPSD	COSMIC;GDSC;CCLE	13.598	Up-regulation
CMGC_CDK_CDK7_CDK7_ST	P11802	CDK4	P50613	CDK7	S243	R246C	246	Missense	distal	3	no	15.913	15.706	EPSD	COSMIC	13.598	Down-regulation
CMGC_CDK_CDK7_CDK7_ST	P11802	CDK4	P50613	CDK7	S243	R246S	246	Missense	distal	3	no	15.913	15.211	EPSD	COSMIC	13.598	Down-regulation
CMGC_CDK_CDK7_CDK7_ST	P11802	CDK4	P50613	CDK7	S243	D241N	241	Missense	proximal	-2	no	15.913	16.345	EPSD	COSMIC	13.598	Up-regulation
CMGC_CDK_CDK7_CDK7_ST	P11802	CDK4	P50613	CDK7	S285	A286T	286	Missense	proximal	1	no	10.175	21.768	EPSD	COSMIC	13.598	Gain
CMGC_CDK_CDK7_CDK7_ST	P11802	CDK4	P50613	CDK7	S293	R288Q	288	Missense	distal	-5	no	15.092	15.014	EPSD	COSMIC	13.598	Down-regulation
CMGC_CDK_CDK7_CDK7_ST	P11802	CDK4	P50613	CDK7	S293	A286T	286	Missense	distal	-7	no	15.092	16.910	EPSD	COSMIC	13.598	Up-regulation
CMGC_CDK_CDK7_CDK7_ST	Q15797	SMAD1	P50613	CDK7	S195	P188S	188	Missense	distal	-7	no	25.333	23.255	EPSD	COSMIC	13.598	Down-regulation
CMGC_CDK_CDK7_CDK7_ST	Q15797	SMAD1	P50613	CDK7	S206	H205Y	205	Missense	proximal	-1	no	24.195	24.577	PhosphoSitePlus	COSMIC	13.598	Up-regulation
CMGC_CDK_CDK7_CDK7_ST	Q15797	SMAD1	P50613	CDK7	S206	H205N	205	Missense	proximal	-1	no	24.195	24.664	PhosphoSitePlus	COSMIC	13.598	Up-regulation
CMGC_CDK_CDK7_CDK7_ST	P06493	CDK1	P50613	CDK7	S46	S53C	53	Missense	distal	7	no	14.793	17.456	EPSD	COSMIC	13.598	Up-regulation
CMGC_CDK_CDK7_CDK7_ST	P06493	CDK1	P50613	CDK7	S53	S53C	53	Missense	central	0	yes	21.987	0.000	EPSD	COSMIC	13.598	Loss
CMGC_CDK_CDK7_CDK7_ST	P06493	CDK1	P50613	CDK7	S208	S208L	208	Missense	central	0	yes	19.691	0.000	EPSD	COSMIC	13.598	Loss
CMGC_CDK_CDK7_CDK7_ST	P06493	CDK1	P50613	CDK7	S208	P202L	202	Missense	distal	-6	no	19.691	19.670	EPSD	COSMIC	13.598	Down-regulation
CMGC_CDK_CDK7_CDK7_ST	Q9BYE7	PCGF6	P50613	CDK7	S30	V29A	29	Missense	proximal	-1	no	24.161	24.421	PhosphoSitePlus	COSMIC	13.598	Up-regulation
CMGC_CDK_CDK7_CDK7_ST	Q9BYE7	PCGF6	P50613	CDK7	S30	T35P	35	Missense	distal	5	no	24.161	24.996	PhosphoSitePlus	COSMIC	13.598	Up-regulation
CMGC_CDK_CDK7_CDK7_ST	Q9BYE7	PCGF6	P50613	CDK7	S30	P26Q	26	Missense	distal	-4	no	24.161	24.079	PhosphoSitePlus	COSMIC	13.598	Down-regulation
CMGC_CDK_CDK7_CDK7_ST	P13631	RARG	P50613	CDK7	S43	P37L	37	Missense	distal	-6	no	21.011	20.990	EPSD	COSMIC	13.598	Down-regulation
CMGC_CDK_CDK7_CDK7_ST	P13631	RARG	P50613	CDK7	S43	L49P	49	Missense	distal	6	no	21.011	20.565	EPSD	COSMIC	13.598	Down-regulation
CMGC_CDK_CDK7_CDK7_ST	P13631	RARG	P50613	CDK7	S43	F46V	46	Missense	distal	3	no	21.011	20.244	EPSD	COSMIC	13.598	Down-regulation
CMGC_CDK_CDK7_CDK7_ST	P13631	RARG	P50613	CDK7	S77	E72K	72	Missense	distal	-5	no	24.662	22.943	EPSD;PhosphoSitePlus	COSMIC	13.598	Down-regulation
CMGC_CDK_CDK7_CDK7_ST	P13631	RARG	P50613	CDK7	S77	P82S	82	Missense	distal	5	no	24.662	26.047	EPSD;PhosphoSitePlus	COSMIC	13.598	Up-regulation
CMGC_CDK_CDK7_CDK7_ST	P13631	RARG	P50613	CDK7	S77	P83L	83	Missense	distal	6	no	24.662	25.108	EPSD;PhosphoSitePlus	COSMIC	13.598	Up-regulation
CMGC_CDK_CDK7_CDK7_ST	P13631	RARG	P50613	CDK7	S79	V86I	86	Missense	distal	7	no	25.233	27.085	PhosphoSitePlus;EPSD	COSMIC	13.598	Up-regulation
CMGC_CDK_CDK7_CDK7_ST	P13631	RARG	P50613	CDK7	S79	E72K	72	Missense	distal	-7	no	25.233	26.883	PhosphoSitePlus;EPSD	COSMIC	13.598	Up-regulation
CMGC_CDK_CDK7_CDK7_ST	P13631	RARG	P50613	CDK7	S79	P82S	82	Missense	distal	3	no	25.233	24.485	PhosphoSitePlus;EPSD	COSMIC	13.598	Down-regulation
CMGC_CDK_CDK7_CDK7_ST	P13631	RARG	P50613	CDK7	S79	P83L	83	Missense	distal	4	no	25.233	23.659	PhosphoSitePlus;EPSD	COSMIC	13.598	Down-regulation
CMGC_CDK_CDK7_CDK7_ST	P13631	RARG	P50613	CDK7	S79	R85Q	85	Missense	distal	6	no	25.233	24.337	PhosphoSitePlus;EPSD	COSMIC	13.598	Down-regulation
CMGC_CDK_CDK7_CDK7_ST	P13631	RARG	P50613	CDK7	S426	G430S	430	Missense	distal	4	no	14.472	14.269	EPSD	COSMIC;GDSC;CCLE	13.598	Down-regulation
CMGC_CDK_CDK7_CDK7_ST	Q9NYV4	CDK12	P50613	CDK7	T57	E59D	59	Missense	proximal	2	no	17.245	18.760	EPSD	COSMIC	13.598	Up-regulation
CMGC_CDK_CDK7_CDK7_ST	Q9NYV4	CDK12	P50613	CDK7	T57	K51R	51	Missense	distal	-6	no	17.245	17.397	EPSD	COSMIC;GDSC;CCLE	13.598	Up-regulation
CMGC_CDK_CDK7_CDK7_ST	Q9NYV4	CDK12	P50613	CDK7	S62	E59D	59	Missense	distal	-3	no	16.417	11.387	EPSD	COSMIC	13.598	Loss
CMGC_CDK_CDK7_CDK7_ST	Q9NYV4	CDK12	P50613	CDK7	T82	S84P	84	Missense	proximal	2	no	13.919	14.416	EPSD	COSMIC	13.598	Up-regulation
CMGC_CDK_CDK7_CDK7_ST	Q9NYV4	CDK12	P50613	CDK7	T82	F89V	89	Missense	distal	7	no	13.919	11.570	EPSD	COSMIC	13.598	Loss
CMGC_CDK_CDK7_CDK7_ST	Q9NYV4	CDK12	P50613	CDK7	S177	E182K	182	Missense	distal	5	no	14.552	13.956	EPSD	COSMIC	13.598	Down-regulation
CMGC_CDK_CDK7_CDK7_ST	Q9NYV4	CDK12	P50613	CDK7	T206	P207S	207	Missense	proximal	1	no	19.298	10.765	EPSD	COSMIC	13.598	Loss
CMGC_CDK_CDK7_CDK7_ST	Q9NYV4	CDK12	P50613	CDK7	S215	R219K	219	Missense	distal	4	no	24.898	23.386	EPSD	COSMIC	13.598	Down-regulation
CMGC_CDK_CDK7_CDK7_ST	Q9NYV4	CDK12	P50613	CDK7	S215	D214N	214	Missense	proximal	-1	no	24.898	25.303	EPSD	COSMIC	13.598	Up-regulation
CMGC_CDK_CDK7_CDK7_ST	Q9NYV4	CDK12	P50613	CDK7	S222	R225G	225	Missense	distal	3	no	15.259	14.507	EPSD	COSMIC	13.598	Down-regulation
CMGC_CDK_CDK7_CDK7_ST	Q9NYV4	CDK12	P50613	CDK7	S222	R219K	219	Missense	distal	-3	no	15.259	11.954	EPSD	COSMIC	13.598	Loss
CMGC_CDK_CDK7_CDK7_ST	Q9NYV4	CDK12	P50613	CDK7	S228	S231C	231	Missense	distal	3	no	13.383	13.878	EPSD	COSMIC;CCLE	13.598	Gain
CMGC_CDK_CDK7_CDK7_ST	Q9NYV4	CDK12	P50613	CDK7	S249	S256W	256	Missense	distal	7	no	13.201	18.013	EPSD	COSMIC	13.598	Gain
CMGC_CDK_CDK7_CDK7_ST	Q9NYV4	CDK12	P50613	CDK7	S287	P294S	294	Missense	distal	7	no	23.902	18.975	EPSD	COSMIC	13.598	Down-regulation
CMGC_CDK_CDK7_CDK7_ST	Q9NYV4	CDK12	P50613	CDK7	S287	Q286E	286	Missense	proximal	-1	no	23.902	23.609	EPSD	COSMIC	13.598	Down-regulation
CMGC_CDK_CDK7_CDK7_ST	Q9NYV4	CDK12	P50613	CDK7	S287	K280R	280	Missense	distal	-7	no	23.902	22.274	EPSD	COSMIC	13.598	Down-regulation
CMGC_CDK_CDK7_CDK7_ST	Q9NYV4	CDK12	P50613	CDK7	S287	E281K	281	Missense	distal	-6	no	23.902	23.608	EPSD	COSMIC	13.598	Down-regulation
CMGC_CDK_CDK7_CDK7_ST	Q9NYV4	CDK12	P50613	CDK7	S291	P294S	294	Missense	distal	3	no	16.900	16.153	EPSD	COSMIC	13.598	Down-regulation
CMGC_CDK_CDK7_CDK7_ST	Q9NYV4	CDK12	P50613	CDK7	S291	Q286E	286	Missense	distal	-5	no	16.900	18.723	EPSD	COSMIC	13.598	Up-regulation
CMGC_CDK_CDK7_CDK7_ST	Q9NYV4	CDK12	P50613	CDK7	S311	S312R	312	Missense	proximal	1	no	24.606	23.560	EPSD	COSMIC	13.598	Down-regulation
CMGC_CDK_CDK7_CDK7_ST	Q9NYV4	CDK12	P50613	CDK7	S311	S316N	316	Missense	distal	5	no	24.606	23.366	EPSD	COSMIC	13.598	Down-regulation
CMGC_CDK_CDK7_CDK7_ST	Q9NYV4	CDK12	P50613	CDK7	S311	E314Q	314	Missense	distal	3	no	24.606	25.415	EPSD	COSMIC	13.598	Up-regulation
CMGC_CDK_CDK7_CDK7_ST	Q9NYV4	CDK12	P50613	CDK7	S311	Y305H	305	Missense	distal	-6	no	24.606	23.960	EPSD	COSMIC	13.598	Down-regulation
CMGC_CDK_CDK7_CDK7_ST	Q9NYV4	CDK12	P50613	CDK7	S318	S312R	312	Missense	distal	-6	no	13.695	13.243	EPSD	COSMIC	13.598	Loss
CMGC_CDK_CDK7_CDK7_ST	Q9NYV4	CDK12	P50613	CDK7	S318	R322Q	322	Missense	distal	4	no	13.695	14.341	EPSD	COSMIC;CCLE	13.598	Up-regulation
CMGC_CDK_CDK7_CDK7_ST	Q9NYV4	CDK12	P50613	CDK7	S318	G321W	321	Missense	distal	3	no	13.695	14.759	EPSD	COSMIC	13.598	Up-regulation
CMGC_CDK_CDK7_CDK7_ST	Q9NYV4	CDK12	P50613	CDK7	S318	S316N	316	Missense	proximal	-2	no	13.695	13.367	EPSD	COSMIC	13.598	Loss
CMGC_CDK_CDK7_CDK7_ST	Q9NYV4	CDK12	P50613	CDK7	S318	S325N	325	Missense	distal	7	no	13.695	14.070	EPSD	COSMIC	13.598	Up-regulation
CMGC_CDK_CDK7_CDK7_ST	Q9NYV4	CDK12	P50613	CDK7	S318	E314Q	314	Missense	distal	-4	no	13.695	13.803	EPSD	COSMIC	13.598	Up-regulation
CMGC_CDK_CDK7_CDK7_ST	Q9NYV4	CDK12	P50613	CDK7	S325	R322Q	322	Missense	distal	-3	no	15.666	11.372	EPSD	COSMIC;CCLE	13.598	Loss
CMGC_CDK_CDK7_CDK7_ST	Q9NYV4	CDK12	P50613	CDK7	S325	G321W	321	Missense	distal	-4	no	15.666	15.846	EPSD	COSMIC	13.598	Up-regulation
CMGC_CDK_CDK7_CDK7_ST	Q9NYV4	CDK12	P50613	CDK7	S325	R329Q	329	Missense	distal	4	no	15.666	16.313	EPSD	COSMIC	13.598	Up-regulation
CMGC_CDK_CDK7_CDK7_ST	Q9NYV4	CDK12	P50613	CDK7	S325	R331W	331	Missense	distal	6	no	15.666	13.193	EPSD	COSMIC	13.598	Loss
CMGC_CDK_CDK7_CDK7_ST	Q9NYV4	CDK12	P50613	CDK7	S325	S325N	325	Missense	central	0	yes	15.666	0.000	EPSD	COSMIC	13.598	Loss
CMGC_CDK_CDK7_CDK7_ST	Q9NYV4	CDK12	P50613	CDK7	S325	S332F	332	Missense	distal	7	no	15.666	20.488	EPSD	COSMIC	13.598	Up-regulation
CMGC_CDK_CDK7_CDK7_ST	Q9NYV4	CDK12	P50613	CDK7	S325	R329L	329	Missense	distal	4	no	15.666	13.641	EPSD	COSMIC	13.598	Down-regulation
CMGC_CDK_CDK7_CDK7_ST	Q9NYV4	CDK12	P50613	CDK7	S333	R340W	340	Missense	distal	7	no	13.774	14.737	EPSD	COSMIC	13.598	Up-regulation
CMGC_CDK_CDK7_CDK7_ST	Q9NYV4	CDK12	P50613	CDK7	S333	R329Q	329	Missense	distal	-4	no	13.774	13.740	EPSD	COSMIC	13.598	Down-regulation
CMGC_CDK_CDK7_CDK7_ST	Q9NYV4	CDK12	P50613	CDK7	S333	R331W	331	Missense	proximal	-2	no	13.774	13.216	EPSD	COSMIC	13.598	Loss
CMGC_CDK_CDK7_CDK7_ST	Q9NYV4	CDK12	P50613	CDK7	S333	S338G	338	Missense	distal	5	no	13.774	12.314	EPSD	COSMIC	13.598	Loss
CMGC_CDK_CDK7_CDK7_ST	Q9NYV4	CDK12	P50613	CDK7	S333	S332F	332	Missense	proximal	-1	no	13.774	13.166	EPSD	COSMIC	13.598	Loss
CMGC_CDK_CDK7_CDK7_ST	Q9NYV4	CDK12	P50613	CDK7	S333	R329L	329	Missense	distal	-4	no	13.774	13.854	EPSD	COSMIC	13.598	Up-regulation
CMGC_CDK_CDK7_CDK7_ST	Q9NYV4	CDK12	P50613	CDK7	S334	R340W	340	Missense	distal	6	no	15.999	13.525	EPSD	COSMIC	13.598	Loss
CMGC_CDK_CDK7_CDK7_ST	Q9NYV4	CDK12	P50613	CDK7	S334	R329Q	329	Missense	distal	-5	no	15.999	15.921	EPSD	COSMIC	13.598	Down-regulation
CMGC_CDK_CDK7_CDK7_ST	Q9NYV4	CDK12	P50613	CDK7	S334	R331W	331	Missense	distal	-3	no	15.999	10.009	EPSD	COSMIC	13.598	Loss
CMGC_CDK_CDK7_CDK7_ST	Q9NYV4	CDK12	P50613	CDK7	S334	S338G	338	Missense	distal	4	no	15.999	16.202	EPSD	COSMIC	13.598	Up-regulation
CMGC_CDK_CDK7_CDK7_ST	Q9NYV4	CDK12	P50613	CDK7	S334	S332F	332	Missense	proximal	-2	no	15.999	15.397	EPSD	COSMIC	13.598	Down-regulation
CMGC_CDK_CDK7_CDK7_ST	Q9NYV4	CDK12	P50613	CDK7	S334	R329L	329	Missense	distal	-5	no	15.999	15.904	EPSD	COSMIC	13.598	Down-regulation
CMGC_CDK_CDK7_CDK7_ST	Q9NYV4	CDK12	P50613	CDK7	S343	R340W	340	Missense	distal	-3	no	13.822	7.832	EPSD	COSMIC	13.598	Loss
CMGC_CDK_CDK7_CDK7_ST	Q9NYV4	CDK12	P50613	CDK7	S343	L347P	347	Missense	distal	4	no	13.822	15.395	EPSD	COSMIC	13.598	Up-regulation
CMGC_CDK_CDK7_CDK7_ST	Q9NYV4	CDK12	P50613	CDK7	S343	S338G	338	Missense	distal	-5	no	13.822	11.141	EPSD	COSMIC	13.598	Loss
CMGC_CDK_CDK7_CDK7_ST	Q9NYV4	CDK12	P50613	CDK7	S343	P348S	348	Missense	distal	5	no	13.822	15.207	EPSD	COSMIC	13.598	Up-regulation
CMGC_CDK_CDK7_CDK7_ST	Q9NYV4	CDK12	P50613	CDK7	S345	R340W	340	Missense	distal	-5	no	15.512	13.614	EPSD	COSMIC	13.598	Down-regulation
CMGC_CDK_CDK7_CDK7_ST	Q9NYV4	CDK12	P50613	CDK7	S345	L347P	347	Missense	proximal	2	no	15.512	15.927	EPSD	COSMIC	13.598	Up-regulation
CMGC_CDK_CDK7_CDK7_ST	Q9NYV4	CDK12	P50613	CDK7	S345	S338G	338	Missense	distal	-7	no	15.512	17.915	EPSD	COSMIC	13.598	Up-regulation
CMGC_CDK_CDK7_CDK7_ST	Q9NYV4	CDK12	P50613	CDK7	S345	S352F	352	Missense	distal	7	no	15.512	20.334	EPSD	COSMIC	13.598	Up-regulation
CMGC_CDK_CDK7_CDK7_ST	Q9NYV4	CDK12	P50613	CDK7	S345	P348S	348	Missense	distal	3	no	15.512	14.765	EPSD	COSMIC	13.598	Down-regulation
CMGC_CDK_CDK7_CDK7_ST	Q9NYV4	CDK12	P50613	CDK7	S349	L347P	347	Missense	proximal	-2	no	15.490	15.273	EPSD	COSMIC	13.598	Down-regulation
CMGC_CDK_CDK7_CDK7_ST	Q9NYV4	CDK12	P50613	CDK7	S349	S352F	352	Missense	distal	3	no	15.490	16.145	EPSD	COSMIC	13.598	Up-regulation
CMGC_CDK_CDK7_CDK7_ST	Q9NYV4	CDK12	P50613	CDK7	S349	P348S	348	Missense	proximal	-1	no	15.490	15.743	EPSD	COSMIC	13.598	Up-regulation
CMGC_CDK_CDK7_CDK7_ST	Q9NYV4	CDK12	P50613	CDK7	T460	T466A	466	Missense	distal	6	no	12.970	14.679	EPSD	COSMIC	13.598	Gain
CMGC_CDK_CDK7_CDK7_ST	Q9NYV4	CDK12	P50613	CDK7	S681	P688S	688	Missense	distal	7	no	13.627	8.701	EPSD	COSMIC;GDSC;CCLE	13.598	Loss
CMGC_CDK_CDK7_CDK7_ST	Q9NYV4	CDK12	P50613	CDK7	S681	P682L	682	Missense	proximal	1	no	13.627	6.156	EPSD	COSMIC	13.598	Loss
CMGC_CDK_CDK7_CDK7_ST	Q9NYV4	CDK12	P50613	CDK7	S681	G678E	678	Missense	distal	-3	no	13.627	17.892	EPSD	COSMIC	13.598	Up-regulation
CMGC_CDK_CDK7_CDK7_ST	Q9NYV4	CDK12	P50613	CDK7	S681	S681F	681	Missense	central	0	yes	13.627	0.000	EPSD	COSMIC	13.598	Loss
CMGC_CDK_CDK7_CDK7_ST	Q9NYV4	CDK12	P50613	CDK7	S681	G677Y	677	Missense	distal	-4	no	13.627	13.145	EPSD	COSMIC	13.598	Loss
CMGC_CDK_CDK7_CDK7_ST	Q9NYV4	CDK12	P50613	CDK7	S685	P688S	688	Missense	distal	3	no	15.799	15.051	EPSD	COSMIC;GDSC;CCLE	13.598	Down-regulation
CMGC_CDK_CDK7_CDK7_ST	Q9NYV4	CDK12	P50613	CDK7	S685	P682L	682	Missense	distal	-3	no	15.799	15.838	EPSD	COSMIC	13.598	Up-regulation
CMGC_CDK_CDK7_CDK7_ST	Q9NYV4	CDK12	P50613	CDK7	S685	G678E	678	Missense	distal	-7	no	15.799	15.481	EPSD	COSMIC	13.598	Down-regulation
CMGC_CDK_CDK7_CDK7_ST	Q9NYV4	CDK12	P50613	CDK7	S685	S681F	681	Missense	distal	-4	no	15.799	16.571	EPSD	COSMIC	13.598	Up-regulation
CMGC_CDK_CDK7_CDK7_ST	Q9NYV4	CDK12	P50613	CDK7	S685	I691V	691	Missense	distal	6	no	15.799	15.650	EPSD	COSMIC	13.598	Down-regulation
CMGC_CDK_CDK7_CDK7_ST	Q9NYV4	CDK12	P50613	CDK7	S838	M840I	840	Missense	proximal	2	no	16.125	16.986	EPSD	COSMIC	13.598	Up-regulation
CMGC_CDK_CDK7_CDK7_ST	Q9NYV4	CDK12	P50613	CDK7	S886	E887K	887	Missense	proximal	1	no	14.165	9.494	EPSD	COSMIC	13.598	Loss
CMGC_CDK_CDK7_CDK7_ST	Q9NYV4	CDK12	P50613	CDK7	S886	Y892C	892	Missense	distal	6	no	14.165	13.915	EPSD	COSMIC	13.598	Down-regulation
CMGC_CDK_CDK7_CDK7_ST	Q9NYV4	CDK12	P50613	CDK7	T893	E887K	887	Missense	distal	-6	no	23.282	22.988	PhosphoSitePlus	COSMIC	13.598	Down-regulation
CMGC_CDK_CDK7_CDK7_ST	Q9NYV4	CDK12	P50613	CDK7	T893	Y892C	892	Missense	proximal	-1	no	23.282	23.022	PhosphoSitePlus	COSMIC	13.598	Down-regulation
CMGC_CDK_CDK7_CDK7_ST	Q9NYV4	CDK12	P50613	CDK7	S949	C956F	956	Missense	distal	7	no	14.633	16.792	EPSD	COSMIC	13.598	Up-regulation
CMGC_CDK_CDK7_CDK7_ST	Q9NYV4	CDK12	P50613	CDK7	S949	S954C	954	Missense	distal	5	no	14.633	13.157	EPSD	COSMIC	13.598	Loss
CMGC_CDK_CDK7_CDK7_ST	Q9NYV4	CDK12	P50613	CDK7	S949	Q944K	944	Missense	distal	-5	no	14.633	14.737	EPSD	COSMIC	13.598	Up-regulation
CMGC_CDK_CDK7_CDK7_ST	Q9NYV4	CDK12	P50613	CDK7	S949	G953S	953	Missense	distal	4	no	14.633	14.429	EPSD	COSMIC	13.598	Down-regulation
CMGC_CDK_CDK7_CDK7_ST	Q9NYV4	CDK12	P50613	CDK7	S954	C956F	956	Missense	proximal	2	no	18.266	19.579	EPSD	COSMIC	13.598	Up-regulation
CMGC_CDK_CDK7_CDK7_ST	Q9NYV4	CDK12	P50613	CDK7	S954	P961R	961	Missense	distal	7	no	18.266	17.189	EPSD	COSMIC	13.598	Down-regulation
CMGC_CDK_CDK7_CDK7_ST	Q9NYV4	CDK12	P50613	CDK7	S954	S954C	954	Missense	central	0	yes	18.266	0.000	EPSD	COSMIC	13.598	Loss
CMGC_CDK_CDK7_CDK7_ST	Q9NYV4	CDK12	P50613	CDK7	S954	G953S	953	Missense	proximal	-1	no	18.266	18.854	EPSD	COSMIC	13.598	Up-regulation
CMGC_CDK_CDK7_CDK7_ST	Q9NYV4	CDK12	P50613	CDK7	S1063	P1062S	1062	Missense	proximal	-1	no	14.709	14.963	EPSD	COSMIC	13.598	Up-regulation
CMGC_CDK_CDK7_CDK7_ST	Q9NYV4	CDK12	P50613	CDK7	S1083	A1085P	1085	Missense	proximal	2	no	16.701	17.561	EPSD	COSMIC	13.598	Up-regulation
CMGC_CDK_CDK7_CDK7_ST	Q9NYV4	CDK12	P50613	CDK7	S1083	P1084Q	1084	Missense	proximal	1	no	16.701	9.425	EPSD	COSMIC	13.598	Loss
CMGC_CDK_CDK7_CDK7_ST	Q9NYV4	CDK12	P50613	CDK7	T1195	S1191L	1191	Missense	distal	-4	no	13.445	13.673	EPSD	COSMIC	13.598	Gain
CMGC_CDK_CDK7_CDK7_ST	Q9NYV4	CDK12	P50613	CDK7	T1244	R1243I	1243	Missense	proximal	-1	no	18.395	18.643	EPSD	COSMIC	13.598	Up-regulation
CMGC_CDK_CDK7_CDK7_ST	Q9NYV4	CDK12	P50613	CDK7	S1365	K1372N	1372	Missense	distal	7	no	14.432	13.513	EPSD	COSMIC	13.598	Loss
CMGC_CDK_CDK7_CDK7_ST	Q9NYV4	CDK12	P50613	CDK7	S1365	G1359D	1359	Missense	distal	-6	no	14.432	14.538	EPSD	COSMIC	13.598	Up-regulation
CMGC_CDK_CDK7_CDK7_ST	P10275	AR	P50613	CDK7	S83	Q79E	79	Missense	distal	-4	no	15.927	15.818	EPSD	COSMIC	13.598	Down-regulation
CMGC_CDK_CDK7_CDK7_ST	P10275	AR	P50613	CDK7	S83	Q86K	86	Missense	distal	3	no	15.927	15.478	EPSD	COSMIC	13.598	Down-regulation
CMGC_CDK_CDK7_CDK7_ST	P10275	AR	P50613	CDK7	S83	E81Q	81	Missense	proximal	-2	no	15.927	15.898	EPSD	COSMIC	13.598	Down-regulation
CMGC_CDK_CDK7_CDK7_ST	P10275	AR	P50613	CDK7	S83	Q90H	90	Missense	distal	7	no	15.927	14.563	EPSD	COSMIC	13.598	Down-regulation
CMGC_CDK_CDK7_CDK7_ST	P10275	AR	P50613	CDK7	S83	Q79R	79	Missense	distal	-4	no	15.927	15.962	EPSD	COSMIC	13.598	Up-regulation
CMGC_CDK_CDK7_CDK7_ST	P10275	AR	P50613	CDK7	S83	P84H	84	Missense	proximal	1	no	15.927	4.489	EPSD	COSMIC	13.598	Loss
CMGC_CDK_CDK7_CDK7_ST	P10275	AR	P50613	CDK7	S258	L257P	257	Missense	proximal	-1	no	23.761	23.789	EPSD	COSMIC	13.598	Up-regulation
CMGC_CDK_CDK7_CDK7_ST	P10275	AR	P50613	CDK7	S258	R264Q	264	Missense	distal	6	no	23.761	22.866	EPSD	COSMIC	13.598	Down-regulation
CMGC_CDK_CDK7_CDK7_ST	P10275	AR	P50613	CDK7	S258	E252G	252	Missense	distal	-6	no	23.761	23.280	EPSD	COSMIC	13.598	Down-regulation
CMGC_CDK_CDK7_CDK7_ST	P10275	AR	P50613	CDK7	S258	E252K	252	Missense	distal	-6	no	23.761	23.467	EPSD	COSMIC	13.598	Down-regulation
CMGC_CDK_CDK7_CDK7_ST	P10275	AR	P50613	CDK7	S258	E255K	255	Missense	distal	-3	no	23.761	21.267	EPSD	COSMIC	13.598	Down-regulation
CMGC_CDK_CDK7_CDK7_ST	P10275	AR	P50613	CDK7	S310	D305N	305	Missense	distal	-5	no	14.097	13.236	EPSD	COSMIC	13.598	Loss
CMGC_CDK_CDK7_CDK7_ST	P10275	AR	P50613	CDK7	S310	S310F	310	Missense	central	0	yes	14.097	0.000	EPSD	COSMIC	13.598	Loss
CMGC_CDK_CDK7_CDK7_ST	P10275	AR	P50613	CDK7	S310	E304K	304	Missense	distal	-6	no	14.097	13.803	EPSD	COSMIC	13.598	Down-regulation
CMGC_CDK_CDK7_CDK7_ST	P10275	AR	P50613	CDK7	S310	T306I	306	Missense	distal	-4	no	14.097	14.635	EPSD	COSMIC;GDSC;CCLE	13.598	Up-regulation
CMGC_CDK_CDK7_CDK7_ST	P10275	AR	P50613	CDK7	S310	F312L	312	Missense	proximal	2	no	14.097	12.518	EPSD	COSMIC	13.598	Loss
CMGC_CDK_CDK7_CDK7_ST	P10275	AR	P50613	CDK7	S516	P515H	515	Missense	proximal	-1	no	26.004	25.787	PhosphoSitePlus	COSMIC	13.598	Down-regulation
CMGC_CDK_CDK7_CDK7_ST	P10275	AR	P50613	CDK7	S516	E523K	523	Missense	distal	7	no	26.004	23.427	PhosphoSitePlus	COSMIC	13.598	Down-regulation
CMGC_CDK_CDK7_CDK7_ST	P10275	AR	P50613	CDK7	S516	P515S	515	Missense	proximal	-1	no	26.004	26.257	PhosphoSitePlus	COSMIC	13.598	Up-regulation
CMGC_CDK_CDK7_CDK7_ST	P10275	AR	P50613	CDK7	S651	A646D	646	Missense	distal	-5	no	14.748	14.808	EPSD	COSMIC	13.598	Up-regulation
CMGC_CDK_CDK7_CDK7_ST	P10275	AR	P50613	CDK7	S651	S648R	648	Missense	distal	-3	no	14.748	18.145	EPSD	COSMIC	13.598	Up-regulation
CMGC_CDK_CDK7_CDK7_ST	P10275	AR	P50613	CDK7	S651	S648N	648	Missense	distal	-3	no	14.748	12.903	EPSD	COSMIC	13.598	Loss
CMGC_CDK_CDK7_CDK7_ST	P10275	AR	P50613	CDK7	S651	E654K	654	Missense	distal	3	no	14.748	15.108	EPSD	COSMIC	13.598	Up-regulation
CMGC_CDK_CDK7_CDK7_ST	P10275	AR	P50613	CDK7	S651	S647F	647	Missense	distal	-4	no	14.748	15.520	EPSD	COSMIC	13.598	Up-regulation
CMGC_CDK_CDK7_CDK7_ST	P10275	AR	P50613	CDK7	S651	E655D	655	Missense	distal	4	no	14.748	17.619	EPSD	COSMIC	13.598	Up-regulation
CMGC_CDK_CDK7_CDK7_ST	P10275	AR	P50613	CDK7	T657	V662A	662	Missense	distal	5	no	12.184	14.226	EPSD	COSMIC	13.598	Gain
AGC_NDR_NDR_STK38_ST	P46937	YAP1	Q15208	STK38	S105	K102R	102	Missense	distal	-3	no	-0.139	0.367	EPSD	COSMIC	0.133	Gain
AGC_NDR_NDR_STK38_ST	P46937	YAP1	Q15208	STK38	S109	R106G	106	Missense	distal	-3	no	2.160	1.620	EPSD;PhosphoSitePlus	COSMIC	0.133	Down-regulation
AGC_NDR_NDR_STK38_ST	P46937	YAP1	Q15208	STK38	S109	K102R	102	Missense	distal	-7	no	2.160	2.157	EPSD;PhosphoSitePlus	COSMIC	0.133	Down-regulation
AGC_NDR_NDR_STK38_ST	P46937	YAP1	Q15208	STK38	S127	Q133H	133	Missense	distal	6	no	2.198	2.200	EPSD;PhosphoSitePlus	COSMIC	0.133	Up-regulation
AGC_NDR_NDR_STK38_ST	P46937	YAP1	Q15208	STK38	S127	S127F	127	Missense	central	0	yes	2.198	0.000	EPSD;PhosphoSitePlus	COSMIC	0.133	Loss
AGC_NDR_NDR_STK38_ST	P46937	YAP1	Q15208	STK38	S127	A125G	125	Missense	proximal	-2	no	2.198	2.195	EPSD;PhosphoSitePlus	COSMIC	0.133	Down-regulation
AGC_NDR_NDR_STK38_ST	P46937	YAP1	Q15208	STK38	S128	A125G	125	Missense	distal	-3	no	0.123	0.142	EPSD	COSMIC	0.133	Gain
AGC_NDR_NDR_STK38_ST	P46937	YAP1	Q15208	STK38	S131	L132R	132	Missense	proximal	1	no	1.533	1.529	EPSD	COSMIC	0.133	Down-regulation
AGC_NDR_NDR_STK38_ST	P46937	YAP1	Q15208	STK38	S131	Q133H	133	Missense	proximal	2	no	1.533	1.529	EPSD	COSMIC	0.133	Down-regulation
AGC_NDR_NDR_STK38_ST	P46937	YAP1	Q15208	STK38	S131	A125G	125	Missense	distal	-6	no	1.533	1.535	EPSD	COSMIC	0.133	Up-regulation
AGC_NDR_NDR_STK38_ST	P46937	YAP1	Q15208	STK38	S138	Q133H	133	Missense	distal	-5	no	-0.133	1.608	EPSD	COSMIC	0.133	Gain
AGC_NDR_NDR_STK38_ST	P46937	YAP1	Q15208	STK38	S164	Q162R	162	Missense	proximal	-2	no	2.147	2.132	EPSD;PhosphoSitePlus	COSMIC	0.133	Down-regulation
AGC_NDR_NDR_STK38_ST	P46937	YAP1	Q15208	STK38	S336	S340A	340	Missense	distal	4	no	0.177	0.176	EPSD	COSMIC;GDSC	0.133	Down-regulation
AGC_NDR_NDR_STK38_ST	P46937	YAP1	Q15208	STK38	T378	T378I	378	Missense	central	0	yes	0.315	0.000	EPSD	COSMIC	0.133	Loss
AGC_NDR_NDR_STK38_ST	P46937	YAP1	Q15208	STK38	T378	T376A	376	Missense	proximal	-2	no	0.315	0.318	EPSD	COSMIC	0.133	Up-regulation
AGC_NDR_NDR_STK38_ST	P46937	YAP1	Q15208	STK38	T378	T378M	378	Missense	central	0	yes	0.315	0.000	EPSD	COSMIC	0.133	Loss
AGC_NDR_NDR_STK38_ST	P46937	YAP1	Q15208	STK38	T378	M377V	377	Missense	proximal	-1	no	0.315	0.317	EPSD	COSMIC	0.133	Up-regulation
AGC_NDR_NDR_STK38_ST	P46937	YAP1	Q15208	STK38	S382	M377V	377	Missense	distal	-5	no	-0.073	0.139	EPSD	COSMIC	0.133	Gain
AGC_NDR_NDR_STK38_ST	P46937	YAP1	Q15208	STK38	S388	D383H	383	Missense	distal	-5	no	-0.133	1.599	EPSD	COSMIC	0.133	Gain
AGC_NDR_NDR_STK38_ST	P46937	YAP1	Q15208	STK38	S397	T390I	390	Missense	distal	-7	no	2.158	2.159	EPSD	COSMIC	0.133	Up-regulation
AGC_NDR_NDR_STK38_ST	P46937	YAP1	Q15208	STK38	S397	E396K	396	Missense	proximal	-1	no	2.158	2.159	EPSD	COSMIC	0.133	Up-regulation
AGC_NDR_NDR_STK38_ST	P46937	YAP1	Q15208	STK38	S397	D399H	399	Missense	proximal	2	no	2.158	2.154	EPSD	COSMIC	0.133	Down-regulation
AGC_NDR_NDR_STK38_ST	P46937	YAP1	Q15208	STK38	S397	D395G	395	Missense	proximal	-2	no	2.158	2.159	EPSD	COSMIC	0.133	Up-regulation
AGC_NDR_NDR_STK38_ST	P46937	YAP1	Q15208	STK38	S432	D427H	427	Missense	distal	-5	no	-0.024	1.708	EPSD	COSMIC	0.133	Gain
AGC_NDR_NDR_STK38_ST	Q15208	STK38	Q15208	STK38	T74	R71Q	71	Missense	distal	-3	no	2.121	1.603	EPSD	COSMIC	0.133	Down-regulation
AGC_NDR_NDR_STK38_ST	Q15208	STK38	Q15208	STK38	S252	P254H	254	Missense	proximal	2	no	0.229	0.225	EPSD	COSMIC	0.133	Down-regulation
AGC_NDR_NDR_STK38_ST	Q15208	STK38	Q15208	STK38	S281	G284C	284	Missense	distal	3	no	0.268	0.267	EPSD;PhosphoSitePlus	COSMIC	0.133	Down-regulation
AGC_NDR_NDR_STK38_ST	Q15208	STK38	Q15208	STK38	T444	R447H	447	Missense	distal	3	no	0.239	0.237	PhosphoSitePlus;EPSD	COSMIC;GDSC;CCLE	0.133	Down-regulation
AGC_NDR_NDR_STK38_ST	Q15208	STK38	Q15208	STK38	T452	R447H	447	Missense	distal	-5	no	0.118	1.588	EPSD	COSMIC;GDSC;CCLE	0.133	Gain
AGC_NDR_NDR_STK38_ST	Q96QF0	RAB3IP	Q15208	STK38	S163	V166A	166	Missense	distal	3	no	0.358	0.360	EPSD	COSMIC	0.133	Up-regulation
AGC_NDR_NDR_STK38_ST	Q96QF0	RAB3IP	Q15208	STK38	S163	R160S	160	Missense	distal	-3	no	0.358	-0.226	EPSD	COSMIC	0.133	Loss
AGC_NDR_NDR_STK38_ST	Q96QF0	RAB3IP	Q15208	STK38	S165	V166A	166	Missense	proximal	1	no	0.642	0.645	EPSD	COSMIC	0.133	Up-regulation
AGC_NDR_NDR_STK38_ST	Q96QF0	RAB3IP	Q15208	STK38	S165	R160S	160	Missense	distal	-5	no	0.642	0.246	EPSD	COSMIC	0.133	Down-regulation
AGC_NDR_NDR_STK38_ST	Q96QF0	RAB3IP	Q15208	STK38	S288	A292V	292	Missense	distal	4	no	2.190	2.189	PhosphoSitePlus	COSMIC	0.133	Down-regulation
AGC_NDR_NDR_STK38_ST	Q02241	KIF23	Q15208	STK38	T83	G80D	80	Missense	distal	-3	no	0.126	0.141	EPSD	COSMIC;GDSC;CCLE	0.133	Gain
AGC_NDR_NDR_STK38_ST	Q02241	KIF23	Q15208	STK38	T292	N291D	291	Missense	proximal	-1	no	0.227	0.226	EPSD	COSMIC	0.133	Down-regulation
AGC_NDR_NDR_STK38_ST	Q02241	KIF23	Q15208	STK38	S298	N291D	291	Missense	distal	-7	no	1.565	1.566	EPSD	COSMIC	0.133	Up-regulation
AGC_NDR_NDR_STK38_ST	Q02241	KIF23	Q15208	STK38	S303	V304M	304	Missense	proximal	1	no	0.260	0.262	EPSD	COSMIC	0.133	Up-regulation
AGC_NDR_NDR_STK38_ST	Q02241	KIF23	Q15208	STK38	S605	R602Q	602	Missense	distal	-3	no	0.331	-0.187	EPSD	COSMIC	0.133	Loss
AGC_NDR_NDR_STK38_ST	Q02241	KIF23	Q15208	STK38	S605	R608C	608	Missense	distal	3	no	0.331	0.333	EPSD	COSMIC	0.133	Up-regulation
AGC_NDR_NDR_STK38_ST	Q02241	KIF23	Q15208	STK38	S684	P687H	687	Missense	distal	3	no	0.350	0.345	EPSD	COSMIC	0.133	Down-regulation
AGC_NDR_NDR_STK38_ST	Q02241	KIF23	Q15208	STK38	S684	P685Q	685	Missense	proximal	1	no	0.350	0.352	EPSD	COSMIC	0.133	Up-regulation
AGC_NDR_NDR_STK38_ST	Q02241	KIF23	Q15208	STK38	S686	P687H	687	Missense	proximal	1	no	0.137	0.125	EPSD	COSMIC	0.133	Loss
AGC_NDR_NDR_STK38_ST	Q02241	KIF23	Q15208	STK38	S686	P685Q	685	Missense	proximal	-1	no	0.137	0.139	EPSD	COSMIC	0.133	Up-regulation
AGC_NDR_NDR_STK38_ST	Q02241	KIF23	Q15208	STK38	S686	L690F	690	Missense	distal	4	no	0.137	0.136	EPSD	COSMIC	0.133	Down-regulation
AGC_NDR_NDR_STK38_ST	Q02241	KIF23	Q15208	STK38	S692	P687H	687	Missense	distal	-5	no	-0.239	1.556	EPSD	COSMIC	0.133	Gain
AGC_NDR_NDR_STK38_ST	Q02241	KIF23	Q15208	STK38	S718	S719N	719	Missense	proximal	1	no	0.148	0.149	EPSD	COSMIC	0.133	Up-regulation
AGC_NDR_NDR_STK38_ST	Q02241	KIF23	Q15208	STK38	S814	R813C	813	Missense	proximal	-1	no	2.152	2.149	PhosphoSitePlus;EPSD	COSMIC	0.133	Down-regulation
AGC_NDR_NDR_STK38_ST	Q02241	KIF23	Q15208	STK38	S814	H809Q	809	Missense	distal	-5	no	2.152	0.410	PhosphoSitePlus;EPSD	COSMIC	0.133	Down-regulation
AGC_NDR_NDR_STK38_ST	Q02241	KIF23	Q15208	STK38	S814	S812L	812	Missense	proximal	-2	no	2.152	2.145	PhosphoSitePlus;EPSD	COSMIC	0.133	Down-regulation
AGC_NDR_NDR_STK38_ST	Q02241	KIF23	Q15208	STK38	T843	V844L	844	Missense	proximal	1	no	0.224	0.223	EPSD	COSMIC	0.133	Down-regulation
AGC_NDR_NDR_STK38_ST	Q02241	KIF23	Q15208	STK38	S845	V844L	844	Missense	proximal	-1	no	1.707	1.703	EPSD	COSMIC	0.133	Down-regulation
AGC_NDR_NDR_STK38_ST	Q02241	KIF23	Q15208	STK38	S845	A847V	847	Missense	proximal	2	no	1.707	1.706	EPSD	COSMIC	0.133	Down-regulation
AGC_NDR_NDR_STK38_ST	Q02241	KIF23	Q15208	STK38	S867	G869W	869	Missense	proximal	2	no	1.609	1.608	EPSD	COSMIC	0.133	Down-regulation
AGC_NDR_NDR_STK38_ST	Q02241	KIF23	Q15208	STK38	S889	G886C	886	Missense	distal	-3	no	0.088	0.134	EPSD	COSMIC	0.133	Gain
AGC_NDR_NDR_STK38_ST	Q02241	KIF23	Q15208	STK38	S912	R907Q	907	Missense	distal	-5	no	0.643	0.372	EPSD	COSMIC	0.133	Down-regulation
AGC_NDR_NDR_STK38_ST	Q02241	KIF23	Q15208	STK38	T913	R907Q	907	Missense	distal	-6	no	0.348	0.350	EPSD	COSMIC	0.133	Up-regulation
AGC_NDR_NDR_STK38_ST	Q02241	KIF23	Q15208	STK38	S934	R932M	932	Missense	proximal	-2	no	0.131	0.143	EPSD	COSMIC	0.133	Gain
AGC_NDR_NDR_STK38_ST	Q02241	KIF23	Q15208	STK38	S934	R932T	932	Missense	proximal	-2	no	0.131	0.145	EPSD	COSMIC	0.133	Gain
CAMK_CAMKL_AMPK_PRKAA1_ST	Q9Y478	PRKAB1	Q13131	PRKAA1	S24	D23N	23	Missense	proximal	-1	no	60.885	60.845	EPSD;PhosphoSitePlus	COSMIC	56.683	Down-regulation
CAMK_CAMKL_AMPK_PRKAA1_ST	Q9Y478	PRKAB1	Q13131	PRKAA1	S24	K29R	29	Missense	distal	5	no	60.885	60.945	EPSD;PhosphoSitePlus	COSMIC	56.683	Up-regulation
CAMK_CAMKL_AMPK_PRKAA1_ST	Q9Y478	PRKAB1	Q13131	PRKAA1	S25	D23N	23	Missense	proximal	-2	no	60.119	61.171	EPSD	COSMIC	56.683	Up-regulation
CAMK_CAMKL_AMPK_PRKAA1_ST	Q9Y478	PRKAB1	Q13131	PRKAA1	S25	K29R	29	Missense	distal	4	no	60.119	60.122	EPSD	COSMIC	56.683	Up-regulation
CAMK_CAMKL_AMPK_PRKAA1_ST	Q9Y478	PRKAB1	Q13131	PRKAA1	T80	G87S	87	Missense	distal	7	no	58.942	58.993	EPSD;PhosphoSitePlus	COSMIC	56.683	Up-regulation
CAMK_CAMKL_AMPK_PRKAA1_ST	Q9Y478	PRKAB1	Q13131	PRKAA1	T80	A75V	75	Missense	distal	-5	no	58.942	57.749	EPSD;PhosphoSitePlus	COSMIC	56.683	Down-regulation
CAMK_CAMKL_AMPK_PRKAA1_ST	Q9Y478	PRKAB1	Q13131	PRKAA1	S96	L103R	103	Missense	distal	7	no	58.453	57.825	EPSD	COSMIC	56.683	Down-regulation
CAMK_CAMKL_AMPK_PRKAA1_ST	Q9Y478	PRKAB1	Q13131	PRKAA1	S101	L103R	103	Missense	proximal	2	no	56.896	57.046	EPSD	COSMIC	56.683	Up-regulation
CAMK_CAMKL_AMPK_PRKAA1_ST	Q9Y478	PRKAB1	Q13131	PRKAA1	S101	P104H	104	Missense	distal	3	no	56.896	54.915	EPSD	COSMIC	56.683	Loss
CAMK_CAMKL_AMPK_PRKAA1_ST	Q9Y478	PRKAB1	Q13131	PRKAA1	S108	L103R	103	Missense	distal	-5	no	64.453	63.276	PhosphoSitePlus;EPSD	COSMIC	56.683	Down-regulation
CAMK_CAMKL_AMPK_PRKAA1_ST	Q9Y478	PRKAB1	Q13131	PRKAA1	S108	N111K	111	Missense	distal	3	no	64.453	63.215	PhosphoSitePlus;EPSD	COSMIC	56.683	Down-regulation
CAMK_CAMKL_AMPK_PRKAA1_ST	Q9Y478	PRKAB1	Q13131	PRKAA1	S108	N110I	110	Missense	proximal	2	no	64.453	64.084	PhosphoSitePlus;EPSD	COSMIC	56.683	Down-regulation
CAMK_CAMKL_AMPK_PRKAA1_ST	Q9Y478	PRKAB1	Q13131	PRKAA1	S108	P104H	104	Missense	distal	-4	no	64.453	63.374	PhosphoSitePlus;EPSD	COSMIC	56.683	Down-regulation
CAMK_CAMKL_AMPK_PRKAA1_ST	Q9Y478	PRKAB1	Q13131	PRKAA1	S138	W133C	133	Missense	distal	-5	no	54.175	58.014	EPSD	COSMIC	56.683	Gain
CAMK_CAMKL_AMPK_PRKAA1_ST	Q9Y478	PRKAB1	Q13131	PRKAA1	S177	C173F	173	Missense	distal	-4	no	61.246	54.023	EPSD;PhosphoSitePlus	COSMIC;GDSC;CCLE	56.683	Loss
CAMK_CAMKL_AMPK_PRKAA1_ST	Q9Y478	PRKAB1	Q13131	PRKAA1	S177	D175N	175	Missense	proximal	-2	no	61.246	62.297	EPSD;PhosphoSitePlus	COSMIC	56.683	Up-regulation
CAMK_CAMKL_AMPK_PRKAA1_ST	Q9Y478	PRKAB1	Q13131	PRKAA1	S177	S182Y	182	Missense	distal	5	no	61.246	61.333	EPSD;PhosphoSitePlus	COSMIC	56.683	Up-regulation
CAMK_CAMKL_AMPK_PRKAA1_ST	Q9Y478	PRKAB1	Q13131	PRKAA1	S177	P183L	183	Missense	distal	6	no	61.246	61.394	EPSD;PhosphoSitePlus	COSMIC	56.683	Up-regulation
CAMK_CAMKL_AMPK_PRKAA1_ST	Q9Y478	PRKAB1	Q13131	PRKAA1	S182	D175N	175	Missense	distal	-7	no	57.293	57.087	EPSD	COSMIC	56.683	Down-regulation
CAMK_CAMKL_AMPK_PRKAA1_ST	Q9Y478	PRKAB1	Q13131	PRKAA1	S182	S182Y	182	Missense	central	0	yes	57.293	0.000	EPSD	COSMIC	56.683	Loss
CAMK_CAMKL_AMPK_PRKAA1_ST	Q9Y478	PRKAB1	Q13131	PRKAA1	S182	P183L	183	Missense	proximal	1	no	57.293	57.000	EPSD	COSMIC	56.683	Down-regulation
CAMK_CAMKL_AMPK_PRKAA1_ST	P10636	MAPT	Q13131	PRKAA1	S171	P175S	175	Missense	distal	4	no	59.279	59.431	EPSD	COSMIC	56.683	Up-regulation
CAMK_CAMKL_AMPK_PRKAA1_ST	P10636	MAPT	Q13131	PRKAA1	S171	A166V	166	Missense	distal	-5	no	59.279	58.086	EPSD	COSMIC;CCLE	56.683	Down-regulation
CAMK_CAMKL_AMPK_PRKAA1_ST	P10636	MAPT	Q13131	PRKAA1	S171	E176G	176	Missense	distal	5	no	59.279	59.281	EPSD	COSMIC	56.683	Up-regulation
CAMK_CAMKL_AMPK_PRKAA1_ST	P10636	MAPT	Q13131	PRKAA1	S171	D177G	177	Missense	distal	6	no	59.279	59.351	EPSD	COSMIC	56.683	Up-regulation
CAMK_CAMKL_AMPK_PRKAA1_ST	P10636	MAPT	Q13131	PRKAA1	S171	E165K	165	Missense	distal	-6	no	59.279	59.649	EPSD	COSMIC	56.683	Up-regulation
CAMK_CAMKL_AMPK_PRKAA1_ST	P10636	MAPT	Q13131	PRKAA1	S171	G172V	172	Missense	proximal	1	no	59.279	58.556	EPSD	COSMIC	56.683	Down-regulation
CAMK_CAMKL_AMPK_PRKAA1_ST	P10636	MAPT	Q13131	PRKAA1	S214	E210Q	210	Missense	distal	-4	no	71.752	70.338	EPSD;PhosphoSitePlus	COSMIC	56.683	Down-regulation
CAMK_CAMKL_AMPK_PRKAA1_ST	P10636	MAPT	Q13131	PRKAA1	S214	G207E	207	Missense	distal	-7	no	71.752	70.547	EPSD;PhosphoSitePlus	COSMIC	56.683	Down-regulation
CAMK_CAMKL_AMPK_PRKAA1_ST	P10636	MAPT	Q13131	PRKAA1	S235	Q230R	230	Missense	distal	-5	no	55.039	60.721	EPSD	COSMIC	56.683	Gain
CAMK_CAMKL_AMPK_PRKAA1_ST	P10636	MAPT	Q13131	PRKAA1	S382	T386I	386	Missense	distal	4	no	55.707	59.730	EPSD	COSMIC	56.683	Gain
CAMK_CAMKL_AMPK_PRKAA1_ST	P10636	MAPT	Q13131	PRKAA1	S382	D389N	389	Missense	distal	7	no	55.707	57.228	EPSD	COSMIC;GDSC;CCLE	56.683	Gain
CAMK_CAMKL_AMPK_PRKAA1_ST	P10636	MAPT	Q13131	PRKAA1	S388	G385V	385	Missense	distal	-3	no	58.314	58.934	EPSD	COSMIC	56.683	Up-regulation
CAMK_CAMKL_AMPK_PRKAA1_ST	P10636	MAPT	Q13131	PRKAA1	S388	T386I	386	Missense	proximal	-2	no	58.314	59.120	EPSD	COSMIC	56.683	Up-regulation
CAMK_CAMKL_AMPK_PRKAA1_ST	P10636	MAPT	Q13131	PRKAA1	S388	D389N	389	Missense	proximal	1	no	58.314	58.299	EPSD	COSMIC;GDSC;CCLE	56.683	Down-regulation
CAMK_CAMKL_AMPK_PRKAA1_ST	P10636	MAPT	Q13131	PRKAA1	T403	L410F	410	Missense	distal	7	no	58.125	56.815	EPSD	COSMIC	56.683	Down-regulation
CAMK_CAMKL_AMPK_PRKAA1_ST	P10636	MAPT	Q13131	PRKAA1	T403	R398C	398	Missense	distal	-5	no	58.125	56.771	EPSD	COSMIC	56.683	Down-regulation
CAMK_CAMKL_AMPK_PRKAA1_ST	P10636	MAPT	Q13131	PRKAA1	T403	S396F	396	Missense	distal	-7	no	58.125	55.532	EPSD	COSMIC	56.683	Loss
CAMK_CAMKL_AMPK_PRKAA1_ST	P10636	MAPT	Q13131	PRKAA1	S451	S447P	447	Missense	distal	-4	no	58.331	57.088	EPSD	COSMIC	56.683	Down-regulation
CAMK_CAMKL_AMPK_PRKAA1_ST	P10636	MAPT	Q13131	PRKAA1	S451	R448Q	448	Missense	distal	-3	no	58.331	50.387	EPSD	COSMIC	56.683	Loss
CAMK_CAMKL_AMPK_PRKAA1_ST	P10636	MAPT	Q13131	PRKAA1	S516	G521V	521	Missense	distal	5	no	62.451	62.441	EPSD	COSMIC	56.683	Down-regulation
CAMK_CAMKL_AMPK_PRKAA1_ST	P10636	MAPT	Q13131	PRKAA1	S516	G518V	518	Missense	proximal	2	no	62.451	63.906	EPSD	COSMIC	56.683	Up-regulation
CAMK_CAMKL_AMPK_PRKAA1_ST	P10636	MAPT	Q13131	PRKAA1	S516	R511C	511	Missense	distal	-5	no	62.451	61.097	EPSD	COSMIC;CCLE	56.683	Down-regulation
CAMK_CAMKL_AMPK_PRKAA1_ST	P10636	MAPT	Q13131	PRKAA1	S516	G509V	509	Missense	distal	-7	no	62.451	60.653	EPSD	COSMIC	56.683	Down-regulation
CAMK_CAMKL_AMPK_PRKAA1_ST	P10636	MAPT	Q13131	PRKAA1	T529	R526H	526	Missense	distal	-3	no	61.774	53.917	EPSD	COSMIC	56.683	Loss
CAMK_CAMKL_AMPK_PRKAA1_ST	P10636	MAPT	Q13131	PRKAA1	T529	R528S	528	Missense	proximal	-1	no	61.774	61.806	EPSD	COSMIC	56.683	Up-regulation
CAMK_CAMKL_AMPK_PRKAA1_ST	P10636	MAPT	Q13131	PRKAA1	T529	P530S	530	Missense	proximal	1	no	61.774	62.406	EPSD	COSMIC	56.683	Up-regulation
CAMK_CAMKL_AMPK_PRKAA1_ST	P10636	MAPT	Q13131	PRKAA1	T529	P536H	536	Missense	distal	7	no	61.774	60.959	EPSD	COSMIC	56.683	Down-regulation
CAMK_CAMKL_AMPK_PRKAA1_ST	P10636	MAPT	Q13131	PRKAA1	T529	P535Q	535	Missense	distal	6	no	61.774	62.111	EPSD	COSMIC	56.683	Up-regulation
CAMK_CAMKL_AMPK_PRKAA1_ST	P10636	MAPT	Q13131	PRKAA1	S531	R526H	526	Missense	distal	-5	no	64.022	58.642	EPSD	COSMIC	56.683	Down-regulation
CAMK_CAMKL_AMPK_PRKAA1_ST	P10636	MAPT	Q13131	PRKAA1	S531	R528S	528	Missense	distal	-3	no	64.022	54.627	EPSD	COSMIC	56.683	Loss
CAMK_CAMKL_AMPK_PRKAA1_ST	P10636	MAPT	Q13131	PRKAA1	S531	P530S	530	Missense	proximal	-1	no	64.022	64.068	EPSD	COSMIC	56.683	Up-regulation
CAMK_CAMKL_AMPK_PRKAA1_ST	P10636	MAPT	Q13131	PRKAA1	S531	P536H	536	Missense	distal	5	no	64.022	63.826	EPSD	COSMIC	56.683	Down-regulation
CAMK_CAMKL_AMPK_PRKAA1_ST	P10636	MAPT	Q13131	PRKAA1	S531	P535Q	535	Missense	distal	4	no	64.022	61.197	EPSD	COSMIC	56.683	Down-regulation
CAMK_CAMKL_AMPK_PRKAA1_ST	P10636	MAPT	Q13131	PRKAA1	S552	P550S	550	Missense	proximal	-2	no	57.936	57.387	EPSD	COSMIC	56.683	Down-regulation
CAMK_CAMKL_AMPK_PRKAA1_ST	P10636	MAPT	Q13131	PRKAA1	S552	R559C	559	Missense	distal	7	no	57.936	57.969	EPSD	COSMIC	56.683	Up-regulation
CAMK_CAMKL_AMPK_PRKAA1_ST	P10636	MAPT	Q13131	PRKAA1	S552	P553R	553	Missense	proximal	1	no	57.936	57.582	EPSD	COSMIC	56.683	Down-regulation
CAMK_CAMKL_AMPK_PRKAA1_ST	P10636	MAPT	Q13131	PRKAA1	S552	P553L	553	Missense	proximal	1	no	57.936	57.643	EPSD	COSMIC	56.683	Down-regulation
CAMK_CAMKL_AMPK_PRKAA1_ST	P10636	MAPT	Q13131	PRKAA1	S552	P549L	549	Missense	distal	-3	no	57.936	56.829	EPSD	COSMIC	56.683	Down-regulation
CAMK_CAMKL_AMPK_PRKAA1_ST	P10636	MAPT	Q13131	PRKAA1	S552	S555F	555	Missense	distal	3	no	57.936	56.728	EPSD	COSMIC	56.683	Down-regulation
CAMK_CAMKL_AMPK_PRKAA1_ST	P10636	MAPT	Q13131	PRKAA1	S552	P553Q	553	Missense	proximal	1	no	57.936	56.702	EPSD	COSMIC	56.683	Down-regulation
CAMK_CAMKL_AMPK_PRKAA1_ST	P10636	MAPT	Q13131	PRKAA1	S558	P553R	553	Missense	distal	-5	no	53.532	57.095	EPSD	COSMIC	56.683	Gain
CAMK_CAMKL_AMPK_PRKAA1_ST	P10636	MAPT	Q13131	PRKAA1	S558	P553L	553	Missense	distal	-5	no	53.532	58.272	EPSD	COSMIC	56.683	Gain
CAMK_CAMKL_AMPK_PRKAA1_ST	P10636	MAPT	Q13131	PRKAA1	T562	V565M	565	Missense	distal	3	no	63.536	58.929	EPSD	COSMIC	56.683	Down-regulation
CAMK_CAMKL_AMPK_PRKAA1_ST	P10636	MAPT	Q13131	PRKAA1	T562	P566S	566	Missense	distal	4	no	63.536	63.688	EPSD	COSMIC	56.683	Up-regulation
CAMK_CAMKL_AMPK_PRKAA1_ST	P10636	MAPT	Q13131	PRKAA1	T562	R559C	559	Missense	distal	-3	no	63.536	49.389	EPSD	COSMIC	56.683	Loss
CAMK_CAMKL_AMPK_PRKAA1_ST	P10636	MAPT	Q13131	PRKAA1	T562	S555F	555	Missense	distal	-7	no	63.536	60.944	EPSD	COSMIC	56.683	Down-regulation
CAMK_CAMKL_AMPK_PRKAA1_ST	P10636	MAPT	Q13131	PRKAA1	T562	P568S	568	Missense	distal	6	no	63.536	63.551	EPSD	COSMIC	56.683	Up-regulation
CAMK_CAMKL_AMPK_PRKAA1_ST	P10636	MAPT	Q13131	PRKAA1	S575	T580N	580	Missense	distal	5	no	69.683	69.600	EPSD	COSMIC	56.683	Down-regulation
CAMK_CAMKL_AMPK_PRKAA1_ST	P10636	MAPT	Q13131	PRKAA1	S575	G578S	578	Missense	distal	3	no	69.683	68.480	EPSD	COSMIC	56.683	Down-regulation
CAMK_CAMKL_AMPK_PRKAA1_ST	P10636	MAPT	Q13131	PRKAA1	S575	K571E	571	Missense	distal	-4	no	69.683	72.808	EPSD	COSMIC	56.683	Up-regulation
CAMK_CAMKL_AMPK_PRKAA1_ST	P10636	MAPT	Q13131	PRKAA1	S575	P568S	568	Missense	distal	-7	no	69.683	71.950	EPSD	COSMIC	56.683	Up-regulation
CAMK_CAMKL_AMPK_PRKAA1_ST	P10636	MAPT	Q13131	PRKAA1	S579	T580N	580	Missense	proximal	1	no	67.909	68.098	EPSD	COSMIC	56.683	Up-regulation
CAMK_CAMKL_AMPK_PRKAA1_ST	P10636	MAPT	Q13131	PRKAA1	S579	G578S	578	Missense	proximal	-1	no	67.909	67.903	EPSD	COSMIC	56.683	Down-regulation
CAMK_CAMKL_AMPK_PRKAA1_ST	P10636	MAPT	Q13131	PRKAA1	S606	C608W	608	Missense	proximal	2	no	55.531	57.007	EPSD	COSMIC	56.683	Gain
CAMK_CAMKL_AMPK_PRKAA1_ST	P10636	MAPT	Q13131	PRKAA1	S606	S610L	610	Missense	distal	4	no	55.531	62.119	EPSD	COSMIC	56.683	Gain
CAMK_CAMKL_AMPK_PRKAA1_ST	P10636	MAPT	Q13131	PRKAA1	S610	C608W	608	Missense	proximal	-2	no	54.788	59.560	EPSD	COSMIC	56.683	Gain
CAMK_CAMKL_AMPK_PRKAA1_ST	P10636	MAPT	Q13131	PRKAA1	S669	S669L	669	Missense	central	0	yes	59.045	0.000	EPSD	COSMIC	56.683	Loss
CAMK_CAMKL_AMPK_PRKAA1_ST	P10636	MAPT	Q13131	PRKAA1	S669	R666K	666	Missense	distal	-3	no	59.045	54.404	EPSD	COSMIC	56.683	Loss
CAMK_CAMKL_AMPK_PRKAA1_ST	P10636	MAPT	Q13131	PRKAA1	S669	D662G	662	Missense	distal	-7	no	59.045	60.349	EPSD	COSMIC	56.683	Up-regulation
CAMK_CAMKL_AMPK_PRKAA1_ST	P10636	MAPT	Q13131	PRKAA1	S669	S673F	673	Missense	distal	4	no	59.045	61.438	EPSD	COSMIC	56.683	Up-regulation
CAMK_CAMKL_AMPK_PRKAA1_ST	P10636	MAPT	Q13131	PRKAA1	S669	K670N	670	Missense	proximal	1	no	59.045	58.312	EPSD	COSMIC	56.683	Down-regulation
CAMK_CAMKL_AMPK_PRKAA1_ST	P10636	MAPT	Q13131	PRKAA1	S669	K664N	664	Missense	distal	-5	no	59.045	44.201	EPSD	COSMIC	56.683	Loss
CAMK_CAMKL_AMPK_PRKAA1_ST	P10636	MAPT	Q13131	PRKAA1	S669	L674Q	674	Missense	distal	5	no	59.045	59.093	EPSD	COSMIC	56.683	Up-regulation
CAMK_CAMKL_AMPK_PRKAA1_ST	P10636	MAPT	Q13131	PRKAA1	S673	V680I	680	Missense	distal	7	no	58.653	59.851	EPSD	COSMIC	56.683	Up-regulation
CAMK_CAMKL_AMPK_PRKAA1_ST	P10636	MAPT	Q13131	PRKAA1	S673	S669L	669	Missense	distal	-4	no	58.653	57.158	EPSD	COSMIC	56.683	Down-regulation
CAMK_CAMKL_AMPK_PRKAA1_ST	P10636	MAPT	Q13131	PRKAA1	S673	R666K	666	Missense	distal	-7	no	58.653	60.256	EPSD	COSMIC	56.683	Up-regulation
CAMK_CAMKL_AMPK_PRKAA1_ST	P10636	MAPT	Q13131	PRKAA1	S673	S673F	673	Missense	central	0	yes	58.653	0.000	EPSD	COSMIC	56.683	Loss
CAMK_CAMKL_AMPK_PRKAA1_ST	P10636	MAPT	Q13131	PRKAA1	S673	K670N	670	Missense	distal	-3	no	58.653	57.358	EPSD	COSMIC	56.683	Down-regulation
CAMK_CAMKL_AMPK_PRKAA1_ST	P10636	MAPT	Q13131	PRKAA1	S673	L674Q	674	Missense	proximal	1	no	58.653	57.712	EPSD	COSMIC	56.683	Down-regulation
CAMK_CAMKL_AMPK_PRKAA1_ST	P10636	MAPT	Q13131	PRKAA1	S713	E708D	708	Missense	distal	-5	no	57.057	53.641	EPSD	COSMIC	56.683	Loss
CAMK_CAMKL_AMPK_PRKAA1_ST	P10636	MAPT	Q13131	PRKAA1	S713	G706R	706	Missense	distal	-7	no	57.057	55.642	EPSD	COSMIC	56.683	Loss
CAMK_CAMKL_AMPK_PRKAA1_ST	P10636	MAPT	Q13131	PRKAA1	S713	V710M	710	Missense	distal	-3	no	57.057	52.589	EPSD	COSMIC	56.683	Loss
CAMK_CAMKL_AMPK_PRKAA1_ST	P10636	MAPT	Q13131	PRKAA1	S713	E708K	708	Missense	distal	-5	no	57.057	54.409	EPSD	COSMIC	56.683	Loss
CAMK_CAMKL_AMPK_PRKAA1_ST	P10636	MAPT	Q13131	PRKAA1	S713	V710A	710	Missense	distal	-3	no	57.057	54.614	EPSD	COSMIC	56.683	Loss
CAMK_CAMKL_AMPK_PRKAA1_ST	P10636	MAPT	Q13131	PRKAA1	S726	G732S	732	Missense	distal	6	no	62.356	62.584	EPSD	COSMIC	56.683	Up-regulation
CAMK_CAMKL_AMPK_PRKAA1_ST	P10636	MAPT	Q13131	PRKAA1	S726	G732C	732	Missense	distal	6	no	62.356	62.808	EPSD	COSMIC	56.683	Up-regulation
CAMK_CAMKL_AMPK_PRKAA1_ST	P10636	MAPT	Q13131	PRKAA1	S726	R723W	723	Missense	distal	-3	no	62.356	-30.644	EPSD	COSMIC	56.683	Loss
CAMK_CAMKL_AMPK_PRKAA1_ST	P10636	MAPT	Q13131	PRKAA1	S726	V728M	728	Missense	proximal	2	no	62.356	61.504	EPSD	COSMIC	56.683	Down-regulation
CAMK_CAMKL_AMPK_PRKAA1_ST	P10636	MAPT	Q13131	PRKAA1	S726	V728A	728	Missense	proximal	2	no	62.356	61.210	EPSD	COSMIC	56.683	Down-regulation
CAMK_CAMKL_AMPK_PRKAA1_ST	P10636	MAPT	Q13131	PRKAA1	S733	V728M	728	Missense	distal	-5	no	53.804	58.501	EPSD	COSMIC	56.683	Gain
CAMK_CAMKL_AMPK_PRKAA1_ST	P10636	MAPT	Q13131	PRKAA1	S750	E748K	748	Missense	proximal	-2	no	56.447	57.722	EPSD	COSMIC	56.683	Gain
CAMK_CAMKL_AMPK_PRKAA1_ST	P10636	MAPT	Q13131	PRKAA1	S750	A743T	743	Missense	distal	-7	no	56.447	57.296	EPSD	COSMIC	56.683	Gain
CAMK_CAMKL_AMPK_PRKAA1_ST	P05091	ALDH2	Q13131	PRKAA1	T429	F427S	427	Missense	proximal	-2	no	56.341	58.539	EPSD	COSMIC	56.683	Gain
CAMK_CAMKL_AMPK_PRKAA1_ST	P05091	ALDH2	Q13131	PRKAA1	T429	I430T	430	Missense	proximal	1	no	56.341	56.877	EPSD	COSMIC;GDSC;CCLE	56.683	Gain
CAMK_CAMKL_AMPK_PRKAA1_ST	P05091	ALDH2	Q13131	PRKAA1	T441	A446G	446	Missense	distal	5	no	66.092	66.002	EPSD	COSMIC	56.683	Down-regulation
CAMK_CAMKL_AMPK_PRKAA1_ST	P05091	ALDH2	Q13131	PRKAA1	T441	A446S	446	Missense	distal	5	no	66.092	66.047	EPSD	COSMIC;CCLE	56.683	Down-regulation
CAMK_CAMKL_AMPK_PRKAA1_ST	Q7Z3C6	ATG9A	Q13131	PRKAA1	S654	R653C	653	Missense	proximal	-1	no	62.685	62.832	EPSD	COSMIC	56.683	Up-regulation
CAMK_CAMKL_AMPK_PRKAA1_ST	Q7Z3C6	ATG9A	Q13131	PRKAA1	S654	P657L	657	Missense	distal	3	no	62.685	62.941	EPSD	COSMIC	56.683	Up-regulation
CAMK_CAMKL_AMPK_PRKAA1_ST	Q7Z3C6	ATG9A	Q13131	PRKAA1	S654	R653G	653	Missense	proximal	-1	no	62.685	62.724	EPSD	COSMIC	56.683	Up-regulation
CAMK_CAMKL_AMPK_PRKAA1_ST	Q7Z3C6	ATG9A	Q13131	PRKAA1	S683	A679V	679	Missense	distal	-4	no	61.978	60.986	EPSD	COSMIC	56.683	Down-regulation
CAMK_CAMKL_AMPK_PRKAA1_ST	Q7Z3C6	ATG9A	Q13131	PRKAA1	S735	G739A	739	Missense	distal	4	no	55.984	59.136	EPSD	COSMIC	56.683	Gain
CAMK_CAMKL_AMPK_PRKAA1_ST	Q7Z3C6	ATG9A	Q13131	PRKAA1	S738	G739A	739	Missense	proximal	1	no	63.700	61.517	EPSD	COSMIC	56.683	Down-regulation
CAMK_CAMKL_AMPK_PRKAA1_ST	Q7Z3C6	ATG9A	Q13131	PRKAA1	S738	D744N	744	Missense	distal	6	no	63.700	63.882	EPSD	COSMIC	56.683	Up-regulation
CAMK_CAMKL_AMPK_PRKAA1_ST	Q7Z3C6	ATG9A	Q13131	PRKAA1	S761	C764F	764	Missense	distal	3	no	63.081	63.704	PhosphoSitePlus	COSMIC;GDSC;CCLE	56.683	Up-regulation
CAMK_CAMKL_AMPK_PRKAA1_ST	Q7Z3C6	ATG9A	Q13131	PRKAA1	S761	R768W	768	Missense	distal	7	no	63.081	63.306	PhosphoSitePlus	COSMIC;GDSC;CCLE	56.683	Up-regulation
CAMK_CAMKL_AMPK_PRKAA1_ST	Q7Z3C6	ATG9A	Q13131	PRKAA1	S799	G792C	792	Missense	distal	-7	no	66.385	63.577	EPSD	COSMIC	56.683	Down-regulation
CAMK_CAMKL_AMPK_PRKAA1_ST	Q7Z3C6	ATG9A	Q13131	PRKAA1	S799	R796S	796	Missense	distal	-3	no	66.385	56.989	EPSD	COSMIC	56.683	Down-regulation
CAMK_CAMKL_AMPK_PRKAA1_ST	Q7Z3C6	ATG9A	Q13131	PRKAA1	S799	V797A	797	Missense	proximal	-2	no	66.385	64.352	EPSD	COSMIC	56.683	Down-regulation
CAMK_CAMKL_AMPK_PRKAA1_ST	Q7Z3C6	ATG9A	Q13131	PRKAA1	S799	G792S	792	Missense	distal	-7	no	66.385	65.965	EPSD	COSMIC	56.683	Down-regulation
CAMK_CAMKL_AMPK_PRKAA1_ST	Q7Z3C6	ATG9A	Q13131	PRKAA1	S799	R803W	803	Missense	distal	4	no	66.385	69.635	EPSD	COSMIC	56.683	Up-regulation
CAMK_CAMKL_AMPK_PRKAA1_ST	Q7Z3C6	ATG9A	Q13131	PRKAA1	S799	P795S	795	Missense	distal	-4	no	66.385	67.628	EPSD	COSMIC	56.683	Up-regulation
CAMK_CAMKL_AMPK_PRKAA1_ST	Q7Z3C6	ATG9A	Q13131	PRKAA1	S828	E831D	831	Missense	distal	3	no	56.617	58.327	EPSD	COSMIC	56.683	Gain
CAMK_CAMKL_AMPK_PRKAA1_ST	Q7Z628	NET1	Q13131	PRKAA1	S51	R47W	47	Missense	distal	-4	no	67.889	59.226	EPSD	COSMIC	56.683	Down-regulation
CAMK_CAMKL_AMPK_PRKAA1_ST	Q7Z628	NET1	Q13131	PRKAA1	S78	V77A	77	Missense	proximal	-1	no	59.453	59.544	EPSD	COSMIC;GDSC;CCLE	56.683	Up-regulation
CAMK_CAMKL_AMPK_PRKAA1_ST	Q7Z628	NET1	Q13131	PRKAA1	S78	D75N	75	Missense	distal	-3	no	59.453	63.369	EPSD	COSMIC	56.683	Up-regulation
CAMK_CAMKL_AMPK_PRKAA1_ST	Q7Z628	NET1	Q13131	PRKAA1	S80	E86K	86	Missense	distal	6	no	62.041	61.813	EPSD	COSMIC	56.683	Down-regulation
CAMK_CAMKL_AMPK_PRKAA1_ST	Q7Z628	NET1	Q13131	PRKAA1	S80	V77A	77	Missense	distal	-3	no	62.041	59.598	EPSD	COSMIC;GDSC;CCLE	56.683	Down-regulation
CAMK_CAMKL_AMPK_PRKAA1_ST	Q7Z628	NET1	Q13131	PRKAA1	S80	D75N	75	Missense	distal	-5	no	62.041	47.965	EPSD	COSMIC	56.683	Loss
CAMK_CAMKL_AMPK_PRKAA1_ST	Q7Z628	NET1	Q13131	PRKAA1	S100	A96V	96	Missense	distal	-4	no	72.161	71.168	PhosphoSitePlus	COSMIC	56.683	Down-regulation
CAMK_CAMKL_AMPK_PRKAA1_ST	Q7Z628	NET1	Q13131	PRKAA1	S451	R453Q	453	Missense	proximal	2	no	58.017	57.540	EPSD	COSMIC	56.683	Down-regulation
CAMK_CAMKL_AMPK_PRKAA1_ST	Q7Z628	NET1	Q13131	PRKAA1	S451	N458I	458	Missense	distal	7	no	58.017	56.623	EPSD	COSMIC	56.683	Loss
CAMK_CAMKL_AMPK_PRKAA1_ST	Q7Z628	NET1	Q13131	PRKAA1	S451	M448I	448	Missense	distal	-3	no	58.017	57.501	EPSD	COSMIC	56.683	Down-regulation
CAMK_CAMKL_AMPK_PRKAA1_ST	Q7Z628	NET1	Q13131	PRKAA1	S539	T533A	533	Missense	distal	-6	no	63.855	64.058	EPSD	COSMIC	56.683	Up-regulation
CAMK_CAMKL_AMPK_PRKAA1_ST	Q7Z628	NET1	Q13131	PRKAA1	S539	T540N	540	Missense	proximal	1	no	63.855	64.044	EPSD	COSMIC	56.683	Up-regulation
CAMK_CAMKL_AMPK_PRKAA1_ST	Q7Z628	NET1	Q13131	PRKAA1	S543	T540N	540	Missense	distal	-3	no	49.843	58.018	EPSD	COSMIC	56.683	Gain
CAMK_CAMKL_AMPK_PRKAA1_ST	P07954	FH	Q13131	PRKAA1	T56	K61N	61	Missense	distal	5	no	64.956	64.944	EPSD	COSMIC	56.683	Down-regulation
CAMK_CAMKL_AMPK_PRKAA1_ST	P07954	FH	Q13131	PRKAA1	T56	R51W	51	Missense	distal	-5	no	64.956	59.763	EPSD	COSMIC	56.683	Down-regulation
CAMK_CAMKL_AMPK_PRKAA1_ST	P07954	FH	Q13131	PRKAA1	T56	D55N	55	Missense	proximal	-1	no	64.956	64.916	EPSD	COSMIC	56.683	Down-regulation
CAMK_CAMKL_AMPK_PRKAA1_ST	P07954	FH	Q13131	PRKAA1	T56	Y54C	54	Missense	proximal	-2	no	64.956	58.168	EPSD	COSMIC	56.683	Down-regulation
CAMK_CAMKL_AMPK_PRKAA1_ST	P07954	FH	Q13131	PRKAA1	S75	Y68C	68	Missense	distal	-7	no	58.340	58.090	PhosphoSitePlus	COSMIC	56.683	Down-regulation
CAMK_CAMKL_AMPK_PRKAA1_ST	P07954	FH	Q13131	PRKAA1	S75	V73A	73	Missense	proximal	-2	no	58.340	56.308	PhosphoSitePlus	COSMIC	56.683	Loss
CAMK_CAMKL_AMPK_PRKAA1_ST	P07954	FH	Q13131	PRKAA1	S75	V73M	73	Missense	proximal	-2	no	58.340	55.919	PhosphoSitePlus	COSMIC	56.683	Loss
CAMK_CAMKL_AMPK_PRKAA1_ST	P07954	FH	Q13131	PRKAA1	S75	G82E	82	Missense	distal	7	no	58.340	57.615	PhosphoSitePlus	COSMIC	56.683	Down-regulation
CAMK_CAMKL_AMPK_PRKAA1_ST	P07954	FH	Q13131	PRKAA1	S75	M77I	77	Missense	proximal	2	no	58.340	57.633	PhosphoSitePlus	COSMIC	56.683	Down-regulation
CAMK_CAMKL_AMPK_PRKAA1_ST	Q8IY63	AMOTL1	Q13131	PRKAA1	T715	I716V	716	Missense	proximal	1	no	55.296	56.739	EPSD	COSMIC	56.683	Gain
CAMK_CAMKL_AMPK_PRKAA1_ST	Q8IY63	AMOTL1	Q13131	PRKAA1	S724	R721W	721	Missense	distal	-3	no	58.458	-34.542	EPSD	COSMIC	56.683	Loss
CAMK_CAMKL_AMPK_PRKAA1_ST	Q8IY63	AMOTL1	Q13131	PRKAA1	S793	S796F	796	Missense	distal	3	no	58.596	57.388	PhosphoSitePlus	COSMIC	56.683	Down-regulation
CAMK_CAMKL_AMPK_PRKAA1_ST	Q8IY63	AMOTL1	Q13131	PRKAA1	S793	R792L	792	Missense	proximal	-1	no	58.596	58.654	PhosphoSitePlus	COSMIC;GDSC;CCLE	56.683	Up-regulation
CAMK_CAMKL_AMPK_PRKAA1_ST	Q8IY63	AMOTL1	Q13131	PRKAA1	S809	S813R	813	Missense	distal	4	no	56.142	57.248	EPSD	COSMIC	56.683	Gain
CAMK_CAMKL_AMPK_PRKAA1_ST	Q8IY63	AMOTL1	Q13131	PRKAA1	S872	S876I	876	Missense	distal	4	no	54.681	58.192	EPSD	COSMIC	56.683	Gain
CAMK_CAMKL_AMPK_PRKAA1_ST	Q8IY63	AMOTL1	Q13131	PRKAA1	S889	R896C	896	Missense	distal	7	no	65.605	65.638	EPSD	COSMIC	56.683	Up-regulation
CAMK_CAMKL_AMPK_PRKAA1_ST	Q8IY63	AMOTL1	Q13131	PRKAA1	S889	R896L	896	Missense	distal	7	no	65.605	66.233	EPSD	COSMIC;GDSC;CCLE	56.683	Up-regulation
CAMK_CAMKL_AMPK_PRKAA1_ST	Q8IY63	AMOTL1	Q13131	PRKAA1	S889	W887C	887	Missense	proximal	-2	no	65.605	60.833	EPSD	COSMIC;GDSC;CCLE	56.683	Down-regulation
CAMK_CAMKL_AMPK_PRKAA1_ST	Q8IY63	AMOTL1	Q13131	PRKAA1	S889	S882R	882	Missense	distal	-7	no	65.605	64.610	EPSD	COSMIC	56.683	Down-regulation
CAMK_CAMKL_AMPK_PRKAA1_ST	Q13131	PRKAA1	Q13131	PRKAA1	T37	G39C	39	Missense	proximal	2	no	56.820	56.032	EPSD	COSMIC	56.683	Loss
CAMK_CAMKL_AMPK_PRKAA1_ST	Q13131	PRKAA1	Q13131	PRKAA1	T37	K42E	42	Missense	distal	5	no	56.820	56.799	EPSD	COSMIC	56.683	Down-regulation
CAMK_CAMKL_AMPK_PRKAA1_ST	Q13131	PRKAA1	Q13131	PRKAA1	T37	G30C	30	Missense	distal	-7	no	56.820	54.012	EPSD	COSMIC	56.683	Loss
CAMK_CAMKL_AMPK_PRKAA1_ST	Q13131	PRKAA1	Q13131	PRKAA1	S65	G70A	70	Missense	distal	5	no	59.336	59.426	EPSD	COSMIC	56.683	Up-regulation
CAMK_CAMKL_AMPK_PRKAA1_ST	Q13131	PRKAA1	Q13131	PRKAA1	S65	R64W	64	Missense	proximal	-1	no	59.336	59.423	EPSD	COSMIC	56.683	Up-regulation
CAMK_CAMKL_AMPK_PRKAA1_ST	Q13131	PRKAA1	Q13131	PRKAA1	S65	R64C	64	Missense	proximal	-1	no	59.336	59.483	EPSD	COSMIC	56.683	Up-regulation
CAMK_CAMKL_AMPK_PRKAA1_ST	Q13131	PRKAA1	Q13131	PRKAA1	S356	F351L	351	Missense	distal	-5	no	52.121	57.645	EPSD	COSMIC	56.683	Gain
CAMK_CAMKL_AMPK_PRKAA1_ST	Q13131	PRKAA1	Q13131	PRKAA1	S360	A354T	354	Missense	distal	-6	no	57.590	57.387	EPSD;PhosphoSitePlus	COSMIC	56.683	Down-regulation
CAMK_CAMKL_AMPK_PRKAA1_ST	Q13131	PRKAA1	Q13131	PRKAA1	S360	D364Y	364	Missense	distal	4	no	57.590	56.105	EPSD;PhosphoSitePlus	COSMIC	56.683	Loss
CAMK_CAMKL_AMPK_PRKAA1_ST	Q13131	PRKAA1	Q13131	PRKAA1	S397	S397A	397	Missense	central	0	yes	61.571	0.000	EPSD	COSMIC	56.683	Loss
CAMK_CAMKL_AMPK_PRKAA1_ST	Q13131	PRKAA1	Q13131	PRKAA1	S397	G401D	401	Missense	distal	4	no	61.571	61.929	EPSD	COSMIC	56.683	Up-regulation
CAMK_CAMKL_AMPK_PRKAA1_ST	Q13131	PRKAA1	Q13131	PRKAA1	S397	K404N	404	Missense	distal	7	no	61.571	63.345	EPSD	COSMIC	56.683	Up-regulation
CAMK_CAMKL_AMPK_PRKAA1_ST	Q13131	PRKAA1	Q13131	PRKAA1	S494	V497A	497	Missense	distal	3	no	60.164	55.288	PhosphoSitePlus;EPSD	COSMIC	56.683	Loss
CAMK_CAMKL_AMPK_PRKAA1_ST	Q13131	PRKAA1	Q13131	PRKAA1	S494	R501G	501	Missense	distal	7	no	60.164	60.699	PhosphoSitePlus;EPSD	COSMIC	56.683	Up-regulation
CAMK_CAMKL_AMPK_PRKAA1_ST	Q13131	PRKAA1	Q13131	PRKAA1	S496	V497A	497	Missense	proximal	1	no	64.289	62.829	EPSD;PhosphoSitePlus	COSMIC	56.683	Down-regulation
CAMK_CAMKL_AMPK_PRKAA1_ST	Q13131	PRKAA1	Q13131	PRKAA1	S496	R501G	501	Missense	distal	5	no	64.289	64.210	EPSD;PhosphoSitePlus	COSMIC	56.683	Down-regulation
CAMK_CAMKL_AMPK_PRKAA1_ST	Q13131	PRKAA1	Q13131	PRKAA1	S508	R501G	501	Missense	distal	-7	no	61.069	62.484	EPSD	COSMIC	56.683	Up-regulation
CAMK_CAMKL_AMPK_PRKAA1_ST	Q13131	PRKAA1	Q13131	PRKAA1	S508	R505K	505	Missense	distal	-3	no	61.069	56.428	EPSD	COSMIC	56.683	Loss
CAMK_CAMKL_AMPK_PRKAA1_ST	Q13131	PRKAA1	Q13131	PRKAA1	S508	R505G	505	Missense	distal	-3	no	61.069	52.034	EPSD	COSMIC	56.683	Loss
CAMK_CAMKL_AMPK_PRKAA1_ST	Q13131	PRKAA1	Q13131	PRKAA1	S517	S524F	524	Missense	distal	7	no	59.979	58.711	EPSD	COSMIC	56.683	Down-regulation
CAMK_CAMKL_AMPK_PRKAA1_ST	Q13131	PRKAA1	Q13131	PRKAA1	S523	S524F	524	Missense	proximal	1	no	52.441	56.981	EPSD	COSMIC	56.683	Gain
CAMK_CAMKL_AMPK_PRKAA1_ST	Q15036	SNX17	Q13131	PRKAA1	S255	E258G	258	Missense	distal	3	no	56.668	58.839	EPSD	COSMIC	56.683	Gain
CAMK_CAMKL_AMPK_PRKAA1_ST	Q15036	SNX17	Q13131	PRKAA1	S255	S249F	249	Missense	distal	-6	no	56.668	56.771	EPSD	COSMIC	56.683	Gain
CAMK_CAMKL_AMPK_PRKAA1_ST	Q15036	SNX17	Q13131	PRKAA1	S312	R314Q	314	Missense	proximal	2	no	65.764	65.287	EPSD	COSMIC	56.683	Down-regulation
CAMK_CAMKL_AMPK_PRKAA1_ST	Q15036	SNX17	Q13131	PRKAA1	S312	R317H	317	Missense	distal	5	no	65.764	65.571	EPSD	COSMIC	56.683	Down-regulation
CAMK_CAMKL_AMPK_PRKAA1_ST	Q15036	SNX17	Q13131	PRKAA1	S312	V315A	315	Missense	distal	3	no	65.764	60.887	EPSD	COSMIC	56.683	Down-regulation
CAMK_CAMKL_AMPK_PRKAA1_ST	Q15036	SNX17	Q13131	PRKAA1	S325	R322Q	322	Missense	distal	-3	no	63.112	55.167	EPSD	COSMIC	56.683	Loss
CAMK_CAMKL_AMPK_PRKAA1_ST	Q15036	SNX17	Q13131	PRKAA1	S388	S391I	391	Missense	distal	3	no	58.391	56.013	EPSD	COSMIC	56.683	Loss
CAMK_CAMKL_AMPK_PRKAA1_ST	Q15036	SNX17	Q13131	PRKAA1	S388	G390S	390	Missense	proximal	2	no	58.391	58.900	EPSD	COSMIC	56.683	Up-regulation
CAMK_CAMKL_AMPK_PRKAA1_ST	Q15036	SNX17	Q13131	PRKAA1	S409	D408A	408	Missense	proximal	-1	no	61.606	61.627	EPSD	COSMIC;CCLE	56.683	Up-regulation
CAMK_CAMKL_AMPK_PRKAA1_ST	Q15036	SNX17	Q13131	PRKAA1	S409	Q410K	410	Missense	proximal	1	no	61.606	63.351	EPSD	COSMIC	56.683	Up-regulation
CAMK_CAMKL_AMPK_PRKAA1_ST	Q15036	SNX17	Q13131	PRKAA1	T425	M429V	429	Missense	distal	4	no	57.049	55.128	EPSD	COSMIC	56.683	Loss
CAMK_CAMKL_AMPK_PRKAA1_ST	Q15036	SNX17	Q13131	PRKAA1	T425	M429I	429	Missense	distal	4	no	57.049	56.549	EPSD	COSMIC	56.683	Loss
CAMK_CAMKL_AMPK_PRKAA1_ST	Q15036	SNX17	Q13131	PRKAA1	S428	M429V	429	Missense	proximal	1	no	60.645	58.466	EPSD	COSMIC	56.683	Down-regulation
CAMK_CAMKL_AMPK_PRKAA1_ST	Q15036	SNX17	Q13131	PRKAA1	S428	M429I	429	Missense	proximal	1	no	60.645	57.023	EPSD	COSMIC	56.683	Down-regulation
CAMK_CAMKL_AMPK_PRKAA1_ST	Q15036	SNX17	Q13131	PRKAA1	S434	M429V	429	Missense	distal	-5	no	59.760	55.064	EPSD	COSMIC	56.683	Loss
CAMK_CAMKL_AMPK_PRKAA1_ST	Q15036	SNX17	Q13131	PRKAA1	S434	M429I	429	Missense	distal	-5	no	59.760	60.506	EPSD	COSMIC	56.683	Up-regulation
CAMK_CAMKL_AMPK_PRKAA1_ST	Q15036	SNX17	Q13131	PRKAA1	S446	D450H	450	Missense	distal	4	no	63.902	62.744	EPSD	COSMIC	56.683	Down-regulation
CAMK_CAMKL_AMPK_PRKAA1_ST	Q9UQL6	HDAC5	Q13131	PRKAA1	S16	L20M	20	Missense	distal	4	no	63.105	60.529	EPSD	COSMIC	56.683	Down-regulation
CAMK_CAMKL_AMPK_PRKAA1_ST	Q9UQL6	HDAC5	Q13131	PRKAA1	S16	R13W	13	Missense	distal	-3	no	63.105	-29.895	EPSD	COSMIC	56.683	Loss
CAMK_CAMKL_AMPK_PRKAA1_ST	Q9UQL6	HDAC5	Q13131	PRKAA1	S16	L17F	17	Missense	proximal	1	no	63.105	68.571	EPSD	COSMIC	56.683	Up-regulation
CAMK_CAMKL_AMPK_PRKAA1_ST	Q9UQL6	HDAC5	Q13131	PRKAA1	S16	E18Q	18	Missense	proximal	2	no	63.105	62.120	EPSD	COSMIC	56.683	Down-regulation
CAMK_CAMKL_AMPK_PRKAA1_ST	Q9UQL6	HDAC5	Q13131	PRKAA1	S16	G12R	12	Missense	distal	-4	no	63.105	66.713	EPSD	COSMIC	56.683	Up-regulation
CAMK_CAMKL_AMPK_PRKAA1_ST	Q9UQL6	HDAC5	Q13131	PRKAA1	S55	R60W	60	Missense	distal	5	no	60.907	60.778	EPSD	COSMIC	56.683	Down-regulation
CAMK_CAMKL_AMPK_PRKAA1_ST	Q9UQL6	HDAC5	Q13131	PRKAA1	S55	P54S	54	Missense	proximal	-1	no	60.907	60.952	EPSD	COSMIC	56.683	Up-regulation
CAMK_CAMKL_AMPK_PRKAA1_ST	Q9UQL6	HDAC5	Q13131	PRKAA1	S55	R60L	60	Missense	distal	5	no	60.907	60.905	EPSD	COSMIC	56.683	Down-regulation
CAMK_CAMKL_AMPK_PRKAA1_ST	Q9UQL6	HDAC5	Q13131	PRKAA1	S55	G51E	51	Missense	distal	-4	no	60.907	64.460	EPSD	COSMIC	56.683	Up-regulation
CAMK_CAMKL_AMPK_PRKAA1_ST	Q9UQL6	HDAC5	Q13131	PRKAA1	S229	S224R	224	Missense	distal	-5	no	55.784	58.790	EPSD	COSMIC	56.683	Gain
CAMK_CAMKL_AMPK_PRKAA1_ST	Q9UQL6	HDAC5	Q13131	PRKAA1	S229	P232T	232	Missense	distal	3	no	55.784	56.957	EPSD	COSMIC	56.683	Gain
CAMK_CAMKL_AMPK_PRKAA1_ST	Q9UQL6	HDAC5	Q13131	PRKAA1	S259	R255C	255	Missense	distal	-4	no	70.371	74.682	EPSD;PhosphoSitePlus	COSMIC	56.683	Up-regulation
CAMK_CAMKL_AMPK_PRKAA1_ST	Q9UQL6	HDAC5	Q13131	PRKAA1	S259	R266C	266	Missense	distal	7	no	70.371	70.404	EPSD;PhosphoSitePlus	COSMIC	56.683	Up-regulation
CAMK_CAMKL_AMPK_PRKAA1_ST	Q9UQL6	HDAC5	Q13131	PRKAA1	S259	R266H	266	Missense	distal	7	no	70.371	69.644	EPSD;PhosphoSitePlus	COSMIC	56.683	Down-regulation
CAMK_CAMKL_AMPK_PRKAA1_ST	Q9UQL6	HDAC5	Q13131	PRKAA1	S279	R284C	284	Missense	distal	5	no	64.124	64.125	EPSD	COSMIC	56.683	Up-regulation
CAMK_CAMKL_AMPK_PRKAA1_ST	Q9UQL6	HDAC5	Q13131	PRKAA1	S279	S279N	279	Missense	central	0	yes	64.124	0.000	EPSD	COSMIC	56.683	Loss
CAMK_CAMKL_AMPK_PRKAA1_ST	Q9UQL6	HDAC5	Q13131	PRKAA1	S279	R284S	284	Missense	distal	5	no	64.124	64.089	EPSD	COSMIC	56.683	Down-regulation
CAMK_CAMKL_AMPK_PRKAA1_ST	Q9UQL6	HDAC5	Q13131	PRKAA1	S498	R491W	491	Missense	distal	-7	no	62.399	64.198	PhosphoSitePlus;EPSD	COSMIC	56.683	Up-regulation
CAMK_CAMKL_AMPK_PRKAA1_ST	Q9UQL6	HDAC5	Q13131	PRKAA1	S661	R658L	658	Missense	distal	-3	no	64.004	54.038	EPSD	COSMIC	56.683	Loss
CAMK_CAMKL_AMPK_PRKAA1_ST	Q9UQL6	HDAC5	Q13131	PRKAA1	S661	R658H	658	Missense	distal	-3	no	64.004	56.148	EPSD	COSMIC	56.683	Loss
CAMK_CAMKL_AMPK_PRKAA1_ST	Q9UQL6	HDAC5	Q13131	PRKAA1	S661	T659S	659	Missense	proximal	-2	no	64.004	66.687	EPSD	COSMIC	56.683	Up-regulation
CAMK_CAMKL_AMPK_PRKAA1_ST	Q9UQL6	HDAC5	Q13131	PRKAA1	S1108	E1106K	1106	Missense	proximal	-2	no	60.786	62.061	EPSD	COSMIC	56.683	Up-regulation
CAMK_CAMKL_AMPK_PRKAA1_ST	Q9UQL6	HDAC5	Q13131	PRKAA1	S1108	A1104T	1104	Missense	distal	-4	no	60.786	59.930	EPSD	COSMIC;CCLE	56.683	Down-regulation
CAMK_CAMKL_AMPK_PRKAA1_ST	Q8NE86	MCU	Q13131	PRKAA1	S57	R54M	54	Missense	distal	-3	no	57.194	44.312	PhosphoSitePlus	COSMIC	56.683	Loss
CAMK_CAMKL_AMPK_PRKAA1_ST	Q8NE86	MCU	Q13131	PRKAA1	S57	G62E	62	Missense	distal	5	no	57.194	57.193	PhosphoSitePlus	COSMIC	56.683	Down-regulation
CAMK_CAMKL_AMPK_PRKAA1_ST	Q8NE86	MCU	Q13131	PRKAA1	T232	G238C	238	Missense	distal	6	no	56.370	56.822	EPSD	COSMIC	56.683	Gain
CAMK_CAMKL_AMPK_PRKAA1_ST	Q8NE86	MCU	Q13131	PRKAA1	T233	A228T	228	Missense	distal	-5	no	58.575	56.583	EPSD	COSMIC	56.683	Loss
CAMK_CAMKL_AMPK_PRKAA1_ST	Q8NE86	MCU	Q13131	PRKAA1	T233	G238C	238	Missense	distal	5	no	58.575	58.655	EPSD	COSMIC	56.683	Up-regulation
CAMK_CAMKL_AMPK_PRKAA1_ST	P04406	GAPDH	Q13131	PRKAA1	S83	I76M	76	Missense	distal	-7	no	57.740	60.519	EPSD	COSMIC	56.683	Up-regulation
CAMK_CAMKL_AMPK_PRKAA1_ST	P04406	GAPDH	Q13131	PRKAA1	S83	R80P	80	Missense	distal	-3	no	57.740	48.881	EPSD	COSMIC	56.683	Loss
CAMK_CAMKL_AMPK_PRKAA1_ST	P04406	GAPDH	Q13131	PRKAA1	S122	K117R	117	Missense	distal	-5	no	57.178	60.268	PhosphoSitePlus	COSMIC	56.683	Up-regulation
CAMK_CAMKL_AMPK_PRKAA1_ST	P04406	GAPDH	Q13131	PRKAA1	S122	G115R	115	Missense	distal	-7	no	57.178	55.763	PhosphoSitePlus	COSMIC	56.683	Loss
CAMK_CAMKL_AMPK_PRKAA1_ST	P04406	GAPDH	Q13131	PRKAA1	S122	I120V	120	Missense	proximal	-2	no	57.178	59.064	PhosphoSitePlus	COSMIC	56.683	Up-regulation
CAMK_CAMKL_AMPK_PRKAA1_ST	P04406	GAPDH	Q13131	PRKAA1	T237	N239K	239	Missense	proximal	2	no	66.762	67.216	EPSD	COSMIC	56.683	Up-regulation
CAMK_CAMKL_AMPK_PRKAA1_ST	P04406	GAPDH	Q13131	PRKAA1	T237	D244N	244	Missense	distal	7	no	66.762	68.283	EPSD	COSMIC	56.683	Up-regulation
CAMK_CAMKL_AMPK_PRKAA1_ST	P04406	GAPDH	Q13131	PRKAA1	S241	N239K	239	Missense	proximal	-2	no	57.768	58.567	EPSD	COSMIC	56.683	Up-regulation
CAMK_CAMKL_AMPK_PRKAA1_ST	P04406	GAPDH	Q13131	PRKAA1	S241	D244N	244	Missense	distal	3	no	57.768	59.022	EPSD	COSMIC	56.683	Up-regulation
CAMK_CAMKL_AMPK_PRKAA1_ST	P04406	GAPDH	Q13131	PRKAA1	S241	R248K	248	Missense	distal	7	no	57.768	56.882	EPSD	COSMIC	56.683	Down-regulation
CAMK_CAMKL_AMPK_PRKAA1_ST	Q06210	GFPT1	Q13131	PRKAA1	S107	P102R	102	Missense	distal	-5	no	54.334	57.897	EPSD	COSMIC	56.683	Gain
CAMK_CAMKL_AMPK_PRKAA1_ST	Q06210	GFPT1	Q13131	PRKAA1	S257	C254R	254	Missense	distal	-3	no	49.798	63.945	EPSD	COSMIC	56.683	Gain
CAMK_CAMKL_AMPK_PRKAA1_ST	Q06210	GFPT1	Q13131	PRKAA1	S261	P267L	267	Missense	distal	6	no	65.769	65.918	EPSD;PhosphoSitePlus	COSMIC	56.683	Up-regulation
CAMK_CAMKL_AMPK_PRKAA1_ST	Q06210	GFPT1	Q13131	PRKAA1	S261	C254R	254	Missense	distal	-7	no	65.769	67.162	EPSD;PhosphoSitePlus	COSMIC	56.683	Up-regulation
CAMK_CAMKL_AMPK_PRKAA1_ST	Q06210	GFPT1	Q13131	PRKAA1	S261	R258L	258	Missense	distal	-3	no	65.769	55.803	EPSD;PhosphoSitePlus	COSMIC	56.683	Loss
CAMK_CAMKL_AMPK_PRKAA1_ST	P29474	NOS3	Q13131	PRKAA1	S260	P265L	265	Missense	distal	5	no	57.537	57.530	EPSD	COSMIC	56.683	Down-regulation
CAMK_CAMKL_AMPK_PRKAA1_ST	P29474	NOS3	Q13131	PRKAA1	S260	D264N	264	Missense	distal	4	no	57.537	56.804	EPSD	COSMIC	56.683	Down-regulation
CAMK_CAMKL_AMPK_PRKAA1_ST	P29474	NOS3	Q13131	PRKAA1	S260	G259V	259	Missense	proximal	-1	no	57.537	57.462	EPSD	COSMIC	56.683	Down-regulation
CAMK_CAMKL_AMPK_PRKAA1_ST	P29474	NOS3	Q13131	PRKAA1	T495	G489S	489	Missense	distal	-6	no	60.541	61.034	EPSD	COSMIC	56.683	Up-regulation
CAMK_CAMKL_AMPK_PRKAA1_ST	P29474	NOS3	Q13131	PRKAA1	T495	G489D	489	Missense	distal	-6	no	60.541	63.420	EPSD	COSMIC	56.683	Up-regulation
CAMK_CAMKL_AMPK_PRKAA1_ST	P29474	NOS3	Q13131	PRKAA1	S615	K610Q	610	Missense	distal	-5	no	58.693	56.101	EPSD	COSMIC	56.683	Loss
CAMK_CAMKL_AMPK_PRKAA1_ST	P29474	NOS3	Q13131	PRKAA1	S633	D637H	637	Missense	distal	4	no	77.542	76.384	EPSD;PhosphoSitePlus	COSMIC	56.683	Down-regulation
CAMK_CAMKL_AMPK_PRKAA1_ST	P29474	NOS3	Q13131	PRKAA1	S633	N635T	635	Missense	proximal	2	no	77.542	78.032	EPSD;PhosphoSitePlus	COSMIC	56.683	Up-regulation
CAMK_CAMKL_AMPK_PRKAA1_ST	P29474	NOS3	Q13131	PRKAA1	S634	D637H	637	Missense	distal	3	no	61.470	56.511	EPSD	COSMIC	56.683	Loss
CAMK_CAMKL_AMPK_PRKAA1_ST	P29474	NOS3	Q13131	PRKAA1	S634	A641T	641	Missense	distal	7	no	61.470	61.096	EPSD	COSMIC	56.683	Down-regulation
CAMK_CAMKL_AMPK_PRKAA1_ST	P29474	NOS3	Q13131	PRKAA1	S634	N635T	635	Missense	proximal	1	no	61.470	61.281	EPSD	COSMIC	56.683	Down-regulation
CAMK_CAMKL_AMPK_PRKAA1_ST	P29474	NOS3	Q13131	PRKAA1	T785	Q788L	788	Missense	distal	3	no	60.258	57.533	EPSD	COSMIC	56.683	Down-regulation
CAMK_CAMKL_AMPK_PRKAA1_ST	P29474	NOS3	Q13131	PRKAA1	T785	R782H	782	Missense	distal	-3	no	60.258	52.401	EPSD	COSMIC;CCLE	56.683	Loss
CAMK_CAMKL_AMPK_PRKAA1_ST	P29474	NOS3	Q13131	PRKAA1	S870	R875Q	875	Missense	distal	5	no	61.669	61.715	EPSD	COSMIC	56.683	Up-regulation
CAMK_CAMKL_AMPK_PRKAA1_ST	P29474	NOS3	Q13131	PRKAA1	S1198	S1198L	1198	Missense	central	0	yes	57.967	0.000	EPSD	COSMIC	56.683	Loss
CAMK_CAMKL_AMPK_PRKAA1_ST	P50552	VASP	Q13131	PRKAA1	T278	G281W	281	Missense	distal	3	no	60.929	61.135	PhosphoSitePlus	COSMIC	56.683	Up-regulation
CAMK_CAMKL_AMPK_PRKAA1_ST	P50552	VASP	Q13131	PRKAA1	S303	S305C	305	Missense	proximal	2	no	56.685	55.388	EPSD	COSMIC	56.683	Loss
CAMK_CAMKL_AMPK_PRKAA1_ST	P50552	VASP	Q13131	PRKAA1	S303	V299F	299	Missense	distal	-4	no	56.685	56.231	EPSD	COSMIC;CCLE	56.683	Loss
CAMK_CAMKL_AMPK_PRKAA1_ST	P50552	VASP	Q13131	PRKAA1	S322	S325L	325	Missense	distal	3	no	67.825	65.843	EPSD	COSMIC	56.683	Down-regulation
CAMK_CAMKL_AMPK_PRKAA1_ST	P50552	VASP	Q13131	PRKAA1	S322	K321E	321	Missense	proximal	-1	no	67.825	67.850	EPSD	COSMIC	56.683	Up-regulation
CAMK_CAMKL_AMPK_PRKAA1_ST	Q9UQK1	PPP1R3C	Q13131	PRKAA1	S33	K37N	37	Missense	distal	4	no	67.935	65.362	EPSD;PhosphoSitePlus	COSMIC	56.683	Down-regulation
CAMK_CAMKL_AMPK_PRKAA1_ST	Q9UQK1	PPP1R3C	Q13131	PRKAA1	T170	E166K	166	Missense	distal	-4	no	70.453	67.328	EPSD	COSMIC	56.683	Down-regulation
CAMK_CAMKL_AMPK_PRKAA1_ST	P23458	JAK1	Q13131	PRKAA1	S228	R232S	232	Missense	distal	4	no	57.763	56.657	EPSD	COSMIC	56.683	Loss
CAMK_CAMKL_AMPK_PRKAA1_ST	P23458	JAK1	Q13131	PRKAA1	S228	L235V	235	Missense	distal	7	no	57.763	55.432	EPSD	COSMIC;CCLE	56.683	Loss
CAMK_CAMKL_AMPK_PRKAA1_ST	P23458	JAK1	Q13131	PRKAA1	S398	L403W	403	Missense	distal	5	no	63.125	62.998	EPSD	COSMIC	56.683	Down-regulation
CAMK_CAMKL_AMPK_PRKAA1_ST	P23458	JAK1	Q13131	PRKAA1	S398	A402P	402	Missense	distal	4	no	63.125	60.916	EPSD	COSMIC	56.683	Down-regulation
CAMK_CAMKL_AMPK_PRKAA1_ST	P23458	JAK1	Q13131	PRKAA1	S398	E400K	400	Missense	proximal	2	no	63.125	62.731	EPSD	COSMIC	56.683	Down-regulation
CAMK_CAMKL_AMPK_PRKAA1_ST	P23458	JAK1	Q13131	PRKAA1	S398	S397C	397	Missense	proximal	-1	no	63.125	63.239	EPSD	COSMIC	56.683	Up-regulation
CAMK_CAMKL_AMPK_PRKAA1_ST	P23458	JAK1	Q13131	PRKAA1	S515	D513N	513	Missense	proximal	-2	no	65.849	66.900	EPSD;PhosphoSitePlus	COSMIC	56.683	Up-regulation
CAMK_CAMKL_AMPK_PRKAA1_ST	P23458	JAK1	Q13131	PRKAA1	S515	S518N	518	Missense	distal	3	no	65.849	67.843	EPSD;PhosphoSitePlus	COSMIC	56.683	Up-regulation
CAMK_CAMKL_AMPK_PRKAA1_ST	P23458	JAK1	Q13131	PRKAA1	S515	H510R	510	Missense	distal	-5	no	65.849	71.229	EPSD;PhosphoSitePlus	COSMIC	56.683	Up-regulation
CAMK_CAMKL_AMPK_PRKAA1_ST	P23458	JAK1	Q13131	PRKAA1	S515	P517S	517	Missense	proximal	2	no	65.849	65.305	EPSD;PhosphoSitePlus	COSMIC	56.683	Down-regulation
CAMK_CAMKL_AMPK_PRKAA1_ST	P23458	JAK1	Q13131	PRKAA1	S515	G520V	520	Missense	distal	5	no	65.849	65.839	EPSD;PhosphoSitePlus	COSMIC	56.683	Down-regulation
CAMK_CAMKL_AMPK_PRKAA1_ST	P23458	JAK1	Q13131	PRKAA1	S518	D513N	513	Missense	distal	-5	no	58.438	44.362	PhosphoSitePlus;EPSD	COSMIC	56.683	Loss
CAMK_CAMKL_AMPK_PRKAA1_ST	P23458	JAK1	Q13131	PRKAA1	S518	S518N	518	Missense	central	0	yes	58.438	0.000	PhosphoSitePlus;EPSD	COSMIC	56.683	Loss
CAMK_CAMKL_AMPK_PRKAA1_ST	P23458	JAK1	Q13131	PRKAA1	S518	P517S	517	Missense	proximal	-1	no	58.438	58.483	PhosphoSitePlus;EPSD	COSMIC	56.683	Up-regulation
CAMK_CAMKL_AMPK_PRKAA1_ST	P23458	JAK1	Q13131	PRKAA1	S518	G520V	520	Missense	proximal	2	no	58.438	59.893	PhosphoSitePlus;EPSD	COSMIC	56.683	Up-regulation
CAMK_CAMKL_AMPK_PRKAA1_ST	P23458	JAK1	Q13131	PRKAA1	S518	M523I	523	Missense	distal	5	no	58.438	58.546	PhosphoSitePlus;EPSD	COSMIC	56.683	Up-regulation
CAMK_CAMKL_AMPK_PRKAA1_ST	P23458	JAK1	Q13131	PRKAA1	S524	P517S	517	Missense	distal	-7	no	55.947	58.214	EPSD	COSMIC	56.683	Gain
CAMK_CAMKL_AMPK_PRKAA1_ST	P23458	JAK1	Q13131	PRKAA1	S524	G520V	520	Missense	distal	-4	no	55.947	57.097	EPSD	COSMIC	56.683	Gain
CAMK_CAMKL_AMPK_PRKAA1_ST	P23458	JAK1	Q13131	PRKAA1	S524	K527N	527	Missense	distal	3	no	55.947	57.184	EPSD	COSMIC	56.683	Gain
CAMK_CAMKL_AMPK_PRKAA1_ST	P23458	JAK1	Q13131	PRKAA1	T687	T687I	687	Missense	central	0	yes	59.014	0.000	EPSD	COSMIC	56.683	Loss
CAMK_CAMKL_AMPK_PRKAA1_ST	P23458	JAK1	Q13131	PRKAA1	T687	S683T	683	Missense	distal	-4	no	59.014	57.758	EPSD	COSMIC	56.683	Down-regulation
CAMK_CAMKL_AMPK_PRKAA1_ST	P23458	JAK1	Q13131	PRKAA1	T1076	S1080L	1080	Missense	distal	4	no	51.031	57.619	EPSD	COSMIC	56.683	Gain
CAMK_CAMKL_AMPK_PRKAA1_ST	P23458	JAK1	Q13131	PRKAA1	T1100	G1097D	1097	Missense	distal	-3	no	58.087	57.269	EPSD	COSMIC	56.683	Down-regulation
CAMK_CAMKL_AMPK_PRKAA1_ST	P23458	JAK1	Q13131	PRKAA1	T1100	M1099T	1099	Missense	proximal	-1	no	58.087	58.012	EPSD	COSMIC	56.683	Down-regulation
CAMK_CAMKL_AMPK_PRKAA1_ST	P23458	JAK1	Q13131	PRKAA1	T1100	G1097V	1097	Missense	distal	-3	no	58.087	58.707	EPSD	COSMIC;CCLE	56.683	Up-regulation
CAMK_CAMKL_AMPK_PRKAA1_ST	P23458	JAK1	Q13131	PRKAA1	T1100	T1095I	1095	Missense	distal	-5	no	58.087	64.329	EPSD	COSMIC	56.683	Up-regulation
CAMK_CAMKL_AMPK_PRKAA1_ST	P23458	JAK1	Q13131	PRKAA1	T1100	G1097S	1097	Missense	distal	-3	no	58.087	57.727	EPSD	COSMIC	56.683	Down-regulation
CAMK_CAMKL_AMPK_PRKAA1_ST	P23458	JAK1	Q13131	PRKAA1	T1100	T1102K	1102	Missense	proximal	2	no	58.087	58.051	EPSD	COSMIC	56.683	Down-regulation
CAMK_CAMKL_AMPK_PRKAA1_ST	P23458	JAK1	Q13131	PRKAA1	T1100	L1104F	1104	Missense	distal	4	no	58.087	53.892	EPSD	COSMIC	56.683	Loss
CAMK_CAMKL_AMPK_PRKAA1_ST	P23458	JAK1	Q13131	PRKAA1	T1100	V1101I	1101	Missense	proximal	1	no	58.087	56.644	EPSD	COSMIC	56.683	Loss
CAMK_CAMKL_AMPK_PRKAA1_ST	P23458	JAK1	Q13131	PRKAA1	T1100	G1097A	1097	Missense	distal	-3	no	58.087	56.265	EPSD	COSMIC	56.683	Loss
CAMK_CAMKL_AMPK_PRKAA1_ST	P46937	YAP1	Q13131	PRKAA1	S61	E62D	62	Missense	proximal	1	no	60.954	61.166	PhosphoSitePlus;EPSD	COSMIC	56.683	Up-regulation
CAMK_CAMKL_AMPK_PRKAA1_ST	P46937	YAP1	Q13131	PRKAA1	S109	R106G	106	Missense	distal	-3	no	59.066	50.031	EPSD	COSMIC	56.683	Loss
CAMK_CAMKL_AMPK_PRKAA1_ST	P46937	YAP1	Q13131	PRKAA1	S109	S105P	105	Missense	distal	-4	no	59.066	57.823	EPSD	COSMIC	56.683	Down-regulation
CAMK_CAMKL_AMPK_PRKAA1_ST	P46937	YAP1	Q13131	PRKAA1	S109	K102R	102	Missense	distal	-7	no	59.066	57.463	EPSD	COSMIC	56.683	Down-regulation
CAMK_CAMKL_AMPK_PRKAA1_ST	P46937	YAP1	Q13131	PRKAA1	T110	R106G	106	Missense	distal	-4	no	56.736	53.129	EPSD	COSMIC	56.683	Loss
CAMK_CAMKL_AMPK_PRKAA1_ST	P46937	YAP1	Q13131	PRKAA1	T110	S105P	105	Missense	distal	-5	no	56.736	56.178	EPSD	COSMIC	56.683	Loss
CAMK_CAMKL_AMPK_PRKAA1_ST	P46937	YAP1	Q13131	PRKAA1	S229	S227L	227	Missense	proximal	-2	no	57.527	55.101	EPSD	COSMIC;GDSC	56.683	Loss
CAMK_CAMKL_AMPK_PRKAA1_ST	P46937	YAP1	Q13131	PRKAA1	S229	M225I	225	Missense	distal	-4	no	57.527	56.196	EPSD	COSMIC	56.683	Loss
CAMK_CAMKL_AMPK_PRKAA1_ST	P46937	YAP1	Q13131	PRKAA1	S229	P233S	233	Missense	distal	4	no	57.527	57.679	EPSD	COSMIC	56.683	Up-regulation
CAMK_CAMKL_AMPK_PRKAA1_ST	P46937	YAP1	Q13131	PRKAA1	S229	L232F	232	Missense	distal	3	no	57.527	58.301	EPSD	COSMIC;GDSC;CCLE	56.683	Up-regulation
CAMK_CAMKL_AMPK_PRKAA1_ST	P46937	YAP1	Q13131	PRKAA1	S229	D234H	234	Missense	distal	5	no	57.527	57.262	EPSD	COSMIC	56.683	Down-regulation
CAMK_CAMKL_AMPK_PRKAA1_ST	P46937	YAP1	Q13131	PRKAA1	S229	P231S	231	Missense	proximal	2	no	57.527	56.983	EPSD	COSMIC	56.683	Down-regulation
CAMK_CAMKL_AMPK_PRKAA1_ST	P46937	YAP1	Q13131	PRKAA1	S366	S371F	371	Missense	distal	5	no	61.578	61.449	EPSD	COSMIC	56.683	Down-regulation
CAMK_CAMKL_AMPK_PRKAA1_ST	P46937	YAP1	Q13131	PRKAA1	S366	S367F	367	Missense	proximal	1	no	61.578	66.118	EPSD	COSMIC	56.683	Up-regulation
CAMK_CAMKL_AMPK_PRKAA1_ST	P46937	YAP1	Q13131	PRKAA1	T378	N380T	380	Missense	proximal	2	no	66.144	66.634	EPSD	COSMIC	56.683	Up-regulation
CAMK_CAMKL_AMPK_PRKAA1_ST	P46937	YAP1	Q13131	PRKAA1	T378	S382C	382	Missense	distal	4	no	66.144	46.396	EPSD	COSMIC	56.683	Loss
CAMK_CAMKL_AMPK_PRKAA1_ST	P46937	YAP1	Q13131	PRKAA1	T378	D383H	383	Missense	distal	5	no	66.144	65.879	EPSD	COSMIC	56.683	Down-regulation
CAMK_CAMKL_AMPK_PRKAA1_ST	P46937	YAP1	Q13131	PRKAA1	T378	T378I	378	Missense	central	0	yes	66.144	0.000	EPSD	COSMIC	56.683	Loss
CAMK_CAMKL_AMPK_PRKAA1_ST	P46937	YAP1	Q13131	PRKAA1	T378	S371F	371	Missense	distal	-7	no	66.144	63.551	EPSD	COSMIC	56.683	Down-regulation
CAMK_CAMKL_AMPK_PRKAA1_ST	P46937	YAP1	Q13131	PRKAA1	T378	D383G	383	Missense	distal	5	no	66.144	65.993	EPSD	COSMIC	56.683	Down-regulation
CAMK_CAMKL_AMPK_PRKAA1_ST	P46937	YAP1	Q13131	PRKAA1	T378	S382T	382	Missense	distal	4	no	66.144	65.633	EPSD	COSMIC	56.683	Down-regulation
CAMK_CAMKL_AMPK_PRKAA1_ST	P46937	YAP1	Q13131	PRKAA1	T378	F385L	385	Missense	distal	7	no	66.144	67.454	EPSD	COSMIC	56.683	Up-regulation
CAMK_CAMKL_AMPK_PRKAA1_ST	P46937	YAP1	Q13131	PRKAA1	T378	T376A	376	Missense	proximal	-2	no	66.144	66.802	EPSD	COSMIC	56.683	Up-regulation
CAMK_CAMKL_AMPK_PRKAA1_ST	P46937	YAP1	Q13131	PRKAA1	T378	T376P	376	Missense	proximal	-2	no	66.144	69.376	EPSD	COSMIC	56.683	Up-regulation
CAMK_CAMKL_AMPK_PRKAA1_ST	P46937	YAP1	Q13131	PRKAA1	T378	T378M	378	Missense	central	0	yes	66.144	0.000	EPSD	COSMIC	56.683	Loss
CAMK_CAMKL_AMPK_PRKAA1_ST	P46937	YAP1	Q13131	PRKAA1	T378	M377V	377	Missense	proximal	-1	no	66.144	66.057	EPSD	COSMIC	56.683	Down-regulation
CAMK_CAMKL_AMPK_PRKAA1_ST	P46937	YAP1	Q13131	PRKAA1	T378	M377I	377	Missense	proximal	-1	no	66.144	66.141	EPSD	COSMIC;GDSC;CCLE	56.683	Down-regulation
CAMK_CAMKL_AMPK_PRKAA1_ST	P46937	YAP1	Q13131	PRKAA1	S382	N380T	380	Missense	proximal	-2	no	61.508	59.485	EPSD	COSMIC	56.683	Down-regulation
CAMK_CAMKL_AMPK_PRKAA1_ST	P46937	YAP1	Q13131	PRKAA1	S382	S382C	382	Missense	central	0	yes	61.508	0.000	EPSD	COSMIC	56.683	Loss
CAMK_CAMKL_AMPK_PRKAA1_ST	P46937	YAP1	Q13131	PRKAA1	S382	L386P	386	Missense	distal	4	no	61.508	54.768	EPSD	COSMIC	56.683	Loss
CAMK_CAMKL_AMPK_PRKAA1_ST	P46937	YAP1	Q13131	PRKAA1	S382	D383H	383	Missense	proximal	1	no	61.508	64.358	EPSD	COSMIC	56.683	Up-regulation
CAMK_CAMKL_AMPK_PRKAA1_ST	P46937	YAP1	Q13131	PRKAA1	S382	T378I	378	Missense	distal	-4	no	61.508	59.965	EPSD	COSMIC	56.683	Down-regulation
CAMK_CAMKL_AMPK_PRKAA1_ST	P46937	YAP1	Q13131	PRKAA1	S382	D383G	383	Missense	proximal	1	no	61.508	62.935	EPSD	COSMIC	56.683	Up-regulation
CAMK_CAMKL_AMPK_PRKAA1_ST	P46937	YAP1	Q13131	PRKAA1	S382	F385L	385	Missense	distal	3	no	61.508	60.734	EPSD	COSMIC	56.683	Down-regulation
CAMK_CAMKL_AMPK_PRKAA1_ST	P46937	YAP1	Q13131	PRKAA1	S382	T376A	376	Missense	distal	-6	no	61.508	61.711	EPSD	COSMIC	56.683	Up-regulation
CAMK_CAMKL_AMPK_PRKAA1_ST	P46937	YAP1	Q13131	PRKAA1	S382	T376P	376	Missense	distal	-6	no	61.508	61.392	EPSD	COSMIC	56.683	Down-regulation
CAMK_CAMKL_AMPK_PRKAA1_ST	P46937	YAP1	Q13131	PRKAA1	S382	T378M	378	Missense	distal	-4	no	61.508	61.296	EPSD	COSMIC	56.683	Down-regulation
CAMK_CAMKL_AMPK_PRKAA1_ST	P46937	YAP1	Q13131	PRKAA1	S382	M377V	377	Missense	distal	-5	no	61.508	56.812	EPSD	COSMIC	56.683	Down-regulation
CAMK_CAMKL_AMPK_PRKAA1_ST	P46937	YAP1	Q13131	PRKAA1	S382	M377I	377	Missense	distal	-5	no	61.508	62.254	EPSD	COSMIC;GDSC;CCLE	56.683	Up-regulation
CAMK_CAMKL_AMPK_PRKAA1_ST	P46937	YAP1	Q13131	PRKAA1	T390	L386P	386	Missense	distal	-4	no	57.287	57.539	EPSD	COSMIC	56.683	Up-regulation
CAMK_CAMKL_AMPK_PRKAA1_ST	P46937	YAP1	Q13131	PRKAA1	T390	D383H	383	Missense	distal	-7	no	57.287	54.152	EPSD	COSMIC	56.683	Loss
CAMK_CAMKL_AMPK_PRKAA1_ST	P46937	YAP1	Q13131	PRKAA1	T390	D383G	383	Missense	distal	-7	no	57.287	58.592	EPSD	COSMIC	56.683	Up-regulation
CAMK_CAMKL_AMPK_PRKAA1_ST	P46937	YAP1	Q13131	PRKAA1	T390	T390I	390	Missense	central	0	yes	57.287	0.000	EPSD	COSMIC	56.683	Loss
CAMK_CAMKL_AMPK_PRKAA1_ST	P46937	YAP1	Q13131	PRKAA1	T390	F385L	385	Missense	distal	-5	no	57.287	62.811	EPSD	COSMIC	56.683	Up-regulation
CAMK_CAMKL_AMPK_PRKAA1_ST	P46937	YAP1	Q13131	PRKAA1	T390	E396K	396	Missense	distal	6	no	57.287	57.059	EPSD	COSMIC	56.683	Down-regulation
CAMK_CAMKL_AMPK_PRKAA1_ST	P46937	YAP1	Q13131	PRKAA1	T390	D395G	395	Missense	distal	5	no	57.287	57.136	EPSD	COSMIC	56.683	Down-regulation
CAMK_CAMKL_AMPK_PRKAA1_ST	P46937	YAP1	Q13131	PRKAA1	S400	D395G	395	Missense	distal	-5	no	56.299	57.148	EPSD	COSMIC	56.683	Gain
CAMK_CAMKL_AMPK_PRKAA1_ST	P46937	YAP1	Q13131	PRKAA1	S406	D399G	399	Missense	distal	-7	no	61.336	62.641	EPSD	COSMIC	56.683	Up-regulation
CAMK_CAMKL_AMPK_PRKAA1_ST	P46937	YAP1	Q13131	PRKAA1	S406	D399H	399	Missense	distal	-7	no	61.336	58.202	EPSD	COSMIC	56.683	Down-regulation
CAMK_CAMKL_AMPK_PRKAA1_ST	P46937	YAP1	Q13131	PRKAA1	S406	R411Q	411	Missense	distal	5	no	61.336	61.382	EPSD	COSMIC	56.683	Up-regulation
CAMK_CAMKL_AMPK_PRKAA1_ST	P46937	YAP1	Q13131	PRKAA1	T412	N418T	418	Missense	distal	6	no	57.206	57.258	EPSD	COSMIC	56.683	Up-regulation
CAMK_CAMKL_AMPK_PRKAA1_ST	P46937	YAP1	Q13131	PRKAA1	T412	F416L	416	Missense	distal	4	no	57.206	61.401	EPSD	COSMIC	56.683	Up-regulation
CAMK_CAMKL_AMPK_PRKAA1_ST	P46937	YAP1	Q13131	PRKAA1	T412	R411Q	411	Missense	proximal	-1	no	57.206	57.234	EPSD	COSMIC	56.683	Up-regulation
CAMK_CAMKL_AMPK_PRKAA1_ST	P46937	YAP1	Q13131	PRKAA1	S499	L501I	501	Missense	proximal	2	no	57.882	57.325	EPSD	COSMIC	56.683	Down-regulation
CAMK_CAMKL_AMPK_PRKAA1_ST	P63244	RACK1	Q13131	PRKAA1	S35	P28S	28	Missense	distal	-7	no	55.717	57.984	EPSD	COSMIC	56.683	Gain
CAMK_CAMKL_AMPK_PRKAA1_ST	P63244	RACK1	Q13131	PRKAA1	S35	R36G	36	Missense	proximal	1	no	55.717	57.291	EPSD	COSMIC	56.683	Gain
CAMK_CAMKL_AMPK_PRKAA1_ST	P63244	RACK1	Q13131	PRKAA1	S35	K38N	38	Missense	distal	3	no	55.717	56.955	EPSD	COSMIC	56.683	Gain
CAMK_CAMKL_AMPK_PRKAA1_ST	P63244	RACK1	Q13131	PRKAA1	T39	A34V	34	Missense	distal	-5	no	60.886	59.693	EPSD	COSMIC	56.683	Down-regulation
CAMK_CAMKL_AMPK_PRKAA1_ST	P63244	RACK1	Q13131	PRKAA1	T39	L45I	45	Missense	distal	6	no	60.886	60.430	EPSD	COSMIC	56.683	Down-regulation
CAMK_CAMKL_AMPK_PRKAA1_ST	P63244	RACK1	Q13131	PRKAA1	T39	A34G	34	Missense	distal	-5	no	60.886	60.371	EPSD	COSMIC	56.683	Down-regulation
CAMK_CAMKL_AMPK_PRKAA1_ST	P63244	RACK1	Q13131	PRKAA1	T39	R36G	36	Missense	distal	-3	no	60.886	51.851	EPSD	COSMIC	56.683	Loss
CAMK_CAMKL_AMPK_PRKAA1_ST	P63244	RACK1	Q13131	PRKAA1	T39	R36P	36	Missense	distal	-3	no	60.886	52.026	EPSD	COSMIC	56.683	Loss
CAMK_CAMKL_AMPK_PRKAA1_ST	P63244	RACK1	Q13131	PRKAA1	T39	K38N	38	Missense	proximal	-1	no	60.886	60.952	EPSD	COSMIC	56.683	Up-regulation
CAMK_CAMKL_AMPK_PRKAA1_ST	P63244	RACK1	Q13131	PRKAA1	T39	I40V	40	Missense	proximal	1	no	60.886	62.329	EPSD	COSMIC;GDSC	56.683	Up-regulation
CAMK_CAMKL_AMPK_PRKAA1_ST	P63244	RACK1	Q13131	PRKAA1	T50	L45I	45	Missense	distal	-5	no	63.304	63.882	PhosphoSitePlus	COSMIC	56.683	Up-regulation
CAMK_CAMKL_AMPK_PRKAA1_ST	P63244	RACK1	Q13131	PRKAA1	T50	T50M	50	Missense	central	0	yes	63.304	0.000	PhosphoSitePlus	COSMIC	56.683	Loss
CAMK_CAMKL_AMPK_PRKAA1_ST	P63244	RACK1	Q13131	PRKAA1	T50	T50A	50	Missense	central	0	yes	63.304	0.000	PhosphoSitePlus	COSMIC	56.683	Loss
CAMK_CAMKL_AMPK_PRKAA1_ST	P63244	RACK1	Q13131	PRKAA1	T50	R57G	57	Missense	distal	7	no	63.304	63.839	PhosphoSitePlus	COSMIC	56.683	Up-regulation
CAMK_CAMKL_AMPK_PRKAA1_ST	P63244	RACK1	Q13131	PRKAA1	T50	R47M	47	Missense	distal	-3	no	63.304	50.421	PhosphoSitePlus	COSMIC	56.683	Loss
CAMK_CAMKL_AMPK_PRKAA1_ST	P63244	RACK1	Q13131	PRKAA1	T50	R57L	57	Missense	distal	7	no	63.304	63.932	PhosphoSitePlus	COSMIC	56.683	Up-regulation
CAMK_CAMKL_AMPK_PRKAA1_ST	P63244	RACK1	Q13131	PRKAA1	T50	E49D	49	Missense	proximal	-1	no	63.304	63.385	PhosphoSitePlus	COSMIC	56.683	Up-regulation
CAMK_CAMKL_AMPK_PRKAA1_ST	P63244	RACK1	Q13131	PRKAA1	S114	R118W	118	Missense	distal	4	no	54.635	57.885	EPSD	COSMIC	56.683	Gain
CAMK_CAMKL_AMPK_PRKAA1_ST	P63244	RACK1	Q13131	PRKAA1	T128	I129F	129	Missense	proximal	1	no	60.448	66.567	EPSD	COSMIC	56.683	Up-regulation
CAMK_CAMKL_AMPK_PRKAA1_ST	P63244	RACK1	Q13131	PRKAA1	T128	W132L	132	Missense	distal	4	no	60.448	62.679	EPSD	COSMIC	56.683	Up-regulation
CAMK_CAMKL_AMPK_PRKAA1_ST	P63244	RACK1	Q13131	PRKAA1	T128	D126H	126	Missense	proximal	-2	no	60.448	58.199	EPSD	COSMIC	56.683	Down-regulation
CAMK_CAMKL_AMPK_PRKAA1_ST	P63244	RACK1	Q13131	PRKAA1	S146	E149Q	149	Missense	distal	3	no	55.285	56.997	EPSD	COSMIC	56.683	Gain
CAMK_CAMKL_AMPK_PRKAA1_ST	Q13950	RUNX2	Q13131	PRKAA1	S28	P29H	29	Missense	proximal	1	no	57.931	60.574	EPSD	COSMIC	56.683	Up-regulation
CAMK_CAMKL_AMPK_PRKAA1_ST	Q13950	RUNX2	Q13131	PRKAA1	S118	D117N	117	Missense	proximal	-1	no	64.740	64.700	PhosphoSitePlus	COSMIC	56.683	Down-regulation
CAMK_CAMKL_AMPK_PRKAA1_ST	Q13950	RUNX2	Q13131	PRKAA1	S118	L122M	122	Missense	distal	4	no	64.740	62.164	PhosphoSitePlus	COSMIC	56.683	Down-regulation
CAMK_CAMKL_AMPK_PRKAA1_ST	Q13950	RUNX2	Q13131	PRKAA1	S196	G189C	189	Missense	distal	-7	no	74.997	72.189	EPSD	COSMIC;CCLE	56.683	Down-regulation
CAMK_CAMKL_AMPK_PRKAA1_ST	Q13950	RUNX2	Q13131	PRKAA1	S196	V203F	203	Missense	distal	7	no	74.997	76.019	EPSD	COSMIC	56.683	Up-regulation
CAMK_CAMKL_AMPK_PRKAA1_ST	Q13950	RUNX2	Q13131	PRKAA1	S196	G192E	192	Missense	distal	-4	no	74.997	78.550	EPSD	COSMIC	56.683	Up-regulation
CAMK_CAMKL_AMPK_PRKAA1_ST	Q13950	RUNX2	Q13131	PRKAA1	S298	S293P	293	Missense	distal	-5	no	60.621	60.063	EPSD	COSMIC	56.683	Down-regulation
CAMK_CAMKL_AMPK_PRKAA1_ST	Q13950	RUNX2	Q13131	PRKAA1	S298	S305F	305	Missense	distal	7	no	60.621	59.353	EPSD	COSMIC	56.683	Down-regulation
CAMK_CAMKL_AMPK_PRKAA1_ST	Q13950	RUNX2	Q13131	PRKAA1	S298	S305T	305	Missense	distal	7	no	60.621	60.375	EPSD	COSMIC	56.683	Down-regulation
CAMK_CAMKL_AMPK_PRKAA1_ST	Q13950	RUNX2	Q13131	PRKAA1	S298	S298F	298	Missense	central	0	yes	60.621	0.000	EPSD	COSMIC	56.683	Loss
CAMK_CAMKL_AMPK_PRKAA1_ST	Q13950	RUNX2	Q13131	PRKAA1	S465	P472T	472	Missense	distal	7	no	56.461	56.713	EPSD	COSMIC	56.683	Gain
CAMK_CAMKL_AMPK_PRKAA1_ST	Q13950	RUNX2	Q13131	PRKAA1	S465	G462E	462	Missense	distal	-3	no	56.461	57.014	EPSD	COSMIC	56.683	Gain
CAMK_CAMKL_AMPK_PRKAA1_ST	Q13950	RUNX2	Q13131	PRKAA1	S465	P466H	466	Missense	proximal	1	no	56.461	59.104	EPSD	COSMIC	56.683	Gain
CAMK_CAMKL_AMPK_PRKAA1_ST	Q13950	RUNX2	Q13131	PRKAA1	S499	S503F	503	Missense	distal	4	no	56.232	58.625	EPSD	COSMIC	56.683	Gain
CAMK_CAMKL_AMPK_PRKAA1_ST	Q13950	RUNX2	Q13131	PRKAA1	S503	S503F	503	Missense	central	0	yes	59.375	0.000	EPSD	COSMIC	56.683	Loss
CAMK_CAMKL_AMPK_PRKAA1_ST	Q13950	RUNX2	Q13131	PRKAA1	S503	A496T	496	Missense	distal	-7	no	59.375	60.225	EPSD	COSMIC	56.683	Up-regulation
CAMK_CAMKL_AMPK_PRKAA1_ST	Q9NYV6	RRN3	Q13131	PRKAA1	S635	T629M	629	Missense	distal	-6	no	58.671	57.364	PhosphoSitePlus	COSMIC	56.683	Down-regulation
CAMK_CAMKL_AMPK_PRKAA1_ST	Q9H0B6	KLC2	Q13131	PRKAA1	T163	L164V	164	Missense	proximal	1	no	67.657	68.447	EPSD	COSMIC	56.683	Up-regulation
CAMK_CAMKL_AMPK_PRKAA1_ST	Q9H0B6	KLC2	Q13131	PRKAA1	T163	P160H	160	Missense	distal	-3	no	67.657	68.660	EPSD	COSMIC	56.683	Up-regulation
CAMK_CAMKL_AMPK_PRKAA1_ST	Q9H0B6	KLC2	Q13131	PRKAA1	S445	A440S	440	Missense	distal	-5	no	61.611	61.100	EPSD	COSMIC	56.683	Down-regulation
CAMK_CAMKL_AMPK_PRKAA1_ST	Q9H0B6	KLC2	Q13131	PRKAA1	S445	V443I	443	Missense	proximal	-2	no	61.611	59.726	EPSD	COSMIC	56.683	Down-regulation
CAMK_CAMKL_AMPK_PRKAA1_ST	Q9H0B6	KLC2	Q13131	PRKAA1	S445	Y438H	438	Missense	distal	-7	no	61.611	59.730	EPSD	COSMIC	56.683	Down-regulation
CAMK_CAMKL_AMPK_PRKAA1_ST	Q9H0B6	KLC2	Q13131	PRKAA1	S445	S445I	445	Missense	central	0	yes	61.611	0.000	EPSD	COSMIC	56.683	Loss
CAMK_CAMKL_AMPK_PRKAA1_ST	Q9H0B6	KLC2	Q13131	PRKAA1	S487	D484G	484	Missense	distal	-3	no	56.829	57.646	EPSD	COSMIC	56.683	Up-regulation
CAMK_CAMKL_AMPK_PRKAA1_ST	Q9H0B6	KLC2	Q13131	PRKAA1	S499	D504H	504	Missense	distal	5	no	59.269	59.005	EPSD	COSMIC;GDSC;CCLE	56.683	Down-regulation
CAMK_CAMKL_AMPK_PRKAA1_ST	Q9H0B6	KLC2	Q13131	PRKAA1	S499	R502L	502	Missense	distal	3	no	59.269	57.938	EPSD	COSMIC	56.683	Down-regulation
CAMK_CAMKL_AMPK_PRKAA1_ST	Q9H0B6	KLC2	Q13131	PRKAA1	S519	E520G	520	Missense	proximal	1	no	55.434	57.073	EPSD	COSMIC	56.683	Gain
CAMK_CAMKL_AMPK_PRKAA1_ST	Q9H0B6	KLC2	Q13131	PRKAA1	S545	S539F	539	Missense	distal	-6	no	79.895	79.998	PhosphoSitePlus;EPSD	COSMIC	56.683	Up-regulation
CAMK_CAMKL_AMPK_PRKAA1_ST	Q9H0B6	KLC2	Q13131	PRKAA1	S545	R550L	550	Missense	distal	5	no	79.895	79.892	PhosphoSitePlus;EPSD	COSMIC;GDSC;CCLE	56.683	Down-regulation
CAMK_CAMKL_AMPK_PRKAA1_ST	Q9H0B6	KLC2	Q13131	PRKAA1	S557	S556C	556	Missense	proximal	-1	no	62.084	62.198	EPSD	COSMIC	56.683	Up-regulation
CAMK_CAMKL_AMPK_PRKAA1_ST	Q9H0B6	KLC2	Q13131	PRKAA1	S557	S556N	556	Missense	proximal	-1	no	62.084	62.044	EPSD	COSMIC	56.683	Down-regulation
CAMK_CAMKL_AMPK_PRKAA1_ST	Q9H0B6	KLC2	Q13131	PRKAA1	S557	R550L	550	Missense	distal	-7	no	62.084	60.652	EPSD	COSMIC;GDSC;CCLE	56.683	Down-regulation
CAMK_CAMKL_AMPK_PRKAA1_ST	Q9H0B6	KLC2	Q13131	PRKAA1	S610	R616Q	616	Missense	distal	6	no	57.916	58.346	EPSD	COSMIC	56.683	Up-regulation
CAMK_CAMKL_AMPK_PRKAA1_ST	P09874	PARP1	Q13131	PRKAA1	S25	P29L	29	Missense	distal	4	no	54.568	61.308	EPSD	COSMIC	56.683	Gain
CAMK_CAMKL_AMPK_PRKAA1_ST	P09874	PARP1	Q13131	PRKAA1	S204	V202A	202	Missense	proximal	-2	no	61.071	59.039	EPSD	COSMIC	56.683	Down-regulation
CAMK_CAMKL_AMPK_PRKAA1_ST	P09874	PARP1	Q13131	PRKAA1	S204	K203R	203	Missense	proximal	-1	no	61.071	61.145	EPSD	COSMIC	56.683	Up-regulation
CAMK_CAMKL_AMPK_PRKAA1_ST	P09874	PARP1	Q13131	PRKAA1	S204	P200S	200	Missense	distal	-4	no	61.071	62.314	EPSD	COSMIC	56.683	Up-regulation
CAMK_CAMKL_AMPK_PRKAA1_ST	P09874	PARP1	Q13131	PRKAA1	S257	K254N	254	Missense	distal	-3	no	65.400	64.105	EPSD	COSMIC	56.683	Down-regulation
CAMK_CAMKL_AMPK_PRKAA1_ST	P09874	PARP1	Q13131	PRKAA1	S257	D260N	260	Missense	distal	3	no	65.400	66.653	EPSD	COSMIC	56.683	Up-regulation
CAMK_CAMKL_AMPK_PRKAA1_ST	P09874	PARP1	Q13131	PRKAA1	S257	L264V	264	Missense	distal	7	no	65.400	63.068	EPSD	COSMIC	56.683	Down-regulation
CAMK_CAMKL_AMPK_PRKAA1_ST	P09874	PARP1	Q13131	PRKAA1	S257	D260G	260	Missense	distal	3	no	65.400	65.862	EPSD	COSMIC	56.683	Up-regulation
CAMK_CAMKL_AMPK_PRKAA1_ST	P09874	PARP1	Q13131	PRKAA1	S257	E263K	263	Missense	distal	6	no	65.400	65.171	EPSD	COSMIC	56.683	Down-regulation
CAMK_CAMKL_AMPK_PRKAA1_ST	P09874	PARP1	Q13131	PRKAA1	S299	P294X	294	Missense	distal	-5	no	58.219	51.433	EPSD	COSMIC	56.683	Loss
CAMK_CAMKL_AMPK_PRKAA1_ST	P09874	PARP1	Q13131	PRKAA1	S299	P294L	294	Missense	distal	-5	no	58.219	62.960	EPSD	COSMIC	56.683	Up-regulation
CAMK_CAMKL_AMPK_PRKAA1_ST	P09874	PARP1	Q13131	PRKAA1	S299	E296K	296	Missense	distal	-3	no	58.219	62.060	EPSD	COSMIC	56.683	Up-regulation
CAMK_CAMKL_AMPK_PRKAA1_ST	P09874	PARP1	Q13131	PRKAA1	S299	Q301K	301	Missense	proximal	2	no	58.219	58.812	EPSD	COSMIC	56.683	Up-regulation
CAMK_CAMKL_AMPK_PRKAA1_ST	P09874	PARP1	Q13131	PRKAA1	S343	R340L	340	Missense	distal	-3	no	60.884	50.917	EPSD	COSMIC	56.683	Loss
CAMK_CAMKL_AMPK_PRKAA1_ST	P09874	PARP1	Q13131	PRKAA1	S343	L348V	348	Missense	distal	5	no	60.884	60.797	EPSD	COSMIC	56.683	Down-regulation
CAMK_CAMKL_AMPK_PRKAA1_ST	P09874	PARP1	Q13131	PRKAA1	S343	L345F	345	Missense	proximal	2	no	60.884	60.648	EPSD	COSMIC	56.683	Down-regulation
CAMK_CAMKL_AMPK_PRKAA1_ST	P09874	PARP1	Q13131	PRKAA1	S343	L348F	348	Missense	distal	5	no	60.884	60.723	EPSD	COSMIC	56.683	Down-regulation
CAMK_CAMKL_AMPK_PRKAA1_ST	P09874	PARP1	Q13131	PRKAA1	T361	R355H	355	Missense	distal	-6	no	60.148	58.614	EPSD	COSMIC	56.683	Down-regulation
CAMK_CAMKL_AMPK_PRKAA1_ST	P09874	PARP1	Q13131	PRKAA1	T361	F357L	357	Missense	distal	-4	no	60.148	60.500	EPSD	COSMIC	56.683	Up-regulation
CAMK_CAMKL_AMPK_PRKAA1_ST	P09874	PARP1	Q13131	PRKAA1	T361	R355C	355	Missense	distal	-6	no	60.148	56.071	EPSD	COSMIC	56.683	Loss
CAMK_CAMKL_AMPK_PRKAA1_ST	P09874	PARP1	Q13131	PRKAA1	T361	P359L	359	Missense	proximal	-2	no	60.148	57.173	EPSD	COSMIC	56.683	Down-regulation
CAMK_CAMKL_AMPK_PRKAA1_ST	P09874	PARP1	Q13131	PRKAA1	T361	T361N	361	Missense	central	0	yes	60.148	0.000	EPSD	COSMIC	56.683	Loss
CAMK_CAMKL_AMPK_PRKAA1_ST	P09874	PARP1	Q13131	PRKAA1	T361	S364F	364	Missense	distal	3	no	60.148	58.939	EPSD	COSMIC	56.683	Down-regulation
CAMK_CAMKL_AMPK_PRKAA1_ST	P09874	PARP1	Q13131	PRKAA1	S391	A384T	384	Missense	distal	-7	no	68.290	69.140	EPSD	COSMIC	56.683	Up-regulation
CAMK_CAMKL_AMPK_PRKAA1_ST	P09874	PARP1	Q13131	PRKAA1	S391	L398F	398	Missense	distal	7	no	68.290	66.980	EPSD	COSMIC	56.683	Down-regulation
CAMK_CAMKL_AMPK_PRKAA1_ST	P09874	PARP1	Q13131	PRKAA1	S391	I395V	395	Missense	distal	4	no	68.290	66.869	EPSD	COSMIC	56.683	Down-regulation
CAMK_CAMKL_AMPK_PRKAA1_ST	P09874	PARP1	Q13131	PRKAA1	S465	K467Q	467	Missense	proximal	2	no	59.342	58.749	EPSD	COSMIC	56.683	Down-regulation
CAMK_CAMKL_AMPK_PRKAA1_ST	P09874	PARP1	Q13131	PRKAA1	S479	H476N	476	Missense	distal	-3	no	54.967	56.888	EPSD	COSMIC;CCLE	56.683	Gain
CAMK_CAMKL_AMPK_PRKAA1_ST	P09874	PARP1	Q13131	PRKAA1	S507	K508T	508	Missense	proximal	1	no	61.478	60.557	EPSD	COSMIC	56.683	Down-regulation
CAMK_CAMKL_AMPK_PRKAA1_ST	P09874	PARP1	Q13131	PRKAA1	S519	S519A	519	Missense	central	0	yes	63.180	0.000	EPSD	COSMIC	56.683	Loss
CAMK_CAMKL_AMPK_PRKAA1_ST	P09874	PARP1	Q13131	PRKAA1	S519	N517S	517	Missense	proximal	-2	no	63.180	63.840	EPSD	COSMIC	56.683	Up-regulation
CAMK_CAMKL_AMPK_PRKAA1_ST	P09874	PARP1	Q13131	PRKAA1	S519	T526I	526	Missense	distal	7	no	63.180	62.334	EPSD	COSMIC	56.683	Down-regulation
CAMK_CAMKL_AMPK_PRKAA1_ST	P09874	PARP1	Q13131	PRKAA1	S606	P605L	605	Missense	proximal	-1	no	58.313	58.384	EPSD	COSMIC	56.683	Up-regulation
CAMK_CAMKL_AMPK_PRKAA1_ST	P09874	PARP1	Q13131	PRKAA1	S606	I611T	611	Missense	distal	5	no	58.313	58.395	EPSD	COSMIC	56.683	Up-regulation
CAMK_CAMKL_AMPK_PRKAA1_ST	P09874	PARP1	Q13131	PRKAA1	S606	E602Q	602	Missense	distal	-4	no	58.313	56.899	EPSD	COSMIC;GDSC;CCLE	56.683	Down-regulation
CAMK_CAMKL_AMPK_PRKAA1_ST	P09874	PARP1	Q13131	PRKAA1	S606	E602K	602	Missense	distal	-4	no	58.313	55.188	EPSD	COSMIC	56.683	Loss
CAMK_CAMKL_AMPK_PRKAA1_ST	P09874	PARP1	Q13131	PRKAA1	S606	D609G	609	Missense	distal	3	no	58.313	58.775	EPSD	COSMIC	56.683	Up-regulation
CAMK_CAMKL_AMPK_PRKAA1_ST	P09874	PARP1	Q13131	PRKAA1	S606	H613R	613	Missense	distal	7	no	58.313	59.040	EPSD	COSMIC	56.683	Up-regulation
CAMK_CAMKL_AMPK_PRKAA1_ST	P09874	PARP1	Q13131	PRKAA1	S681	F677Y	677	Missense	distal	-4	no	69.737	68.723	EPSD	COSMIC	56.683	Down-regulation
CAMK_CAMKL_AMPK_PRKAA1_ST	P09874	PARP1	Q13131	PRKAA1	S681	A685V	685	Missense	distal	4	no	69.737	69.770	EPSD	COSMIC	56.683	Up-regulation
CAMK_CAMKL_AMPK_PRKAA1_ST	P09874	PARP1	Q13131	PRKAA1	S681	D678G	678	Missense	distal	-3	no	69.737	70.554	EPSD	COSMIC	56.683	Up-regulation
CAMK_CAMKL_AMPK_PRKAA1_ST	P09874	PARP1	Q13131	PRKAA1	S681	E680K	680	Missense	proximal	-1	no	69.737	69.712	EPSD	COSMIC	56.683	Down-regulation
CAMK_CAMKL_AMPK_PRKAA1_ST	P52292	KPNA2	Q13131	PRKAA1	S54	S55L	55	Missense	proximal	1	no	64.161	63.236	EPSD	COSMIC	56.683	Down-regulation
CAMK_CAMKL_AMPK_PRKAA1_ST	P52292	KPNA2	Q13131	PRKAA1	S55	S55L	55	Missense	central	0	yes	58.087	0.000	EPSD	COSMIC	56.683	Loss
CAMK_CAMKL_AMPK_PRKAA1_ST	P52292	KPNA2	Q13131	PRKAA1	T232	T230S	230	Missense	proximal	-2	no	58.401	61.084	EPSD	COSMIC	56.683	Up-regulation
CAMK_CAMKL_AMPK_PRKAA1_ST	P52292	KPNA2	Q13131	PRKAA1	T232	R227H	227	Missense	distal	-5	no	58.401	53.020	EPSD	COSMIC	56.683	Loss
CAMK_CAMKL_AMPK_PRKAA1_ST	O00418	EEF2K	Q13131	PRKAA1	S61	V56L	56	Missense	distal	-5	no	54.048	58.912	EPSD	COSMIC	56.683	Gain
CAMK_CAMKL_AMPK_PRKAA1_ST	O00418	EEF2K	Q13131	PRKAA1	S359	T364N	364	Missense	distal	5	no	60.593	60.510	EPSD	COSMIC	56.683	Down-regulation
CAMK_CAMKL_AMPK_PRKAA1_ST	O00418	EEF2K	Q13131	PRKAA1	S359	E355K	355	Missense	distal	-4	no	60.593	57.468	EPSD	COSMIC	56.683	Down-regulation
CAMK_CAMKL_AMPK_PRKAA1_ST	O00418	EEF2K	Q13131	PRKAA1	S368	T364N	364	Missense	distal	-4	no	56.835	53.292	EPSD	COSMIC	56.683	Loss
CAMK_CAMKL_AMPK_PRKAA1_ST	O00418	EEF2K	Q13131	PRKAA1	S368	P375S	375	Missense	distal	7	no	56.835	57.333	EPSD	COSMIC	56.683	Up-regulation
CAMK_CAMKL_AMPK_PRKAA1_ST	O00418	EEF2K	Q13131	PRKAA1	S377	E383D	383	Missense	distal	6	no	58.008	57.536	EPSD	COSMIC	56.683	Down-regulation
CAMK_CAMKL_AMPK_PRKAA1_ST	O00418	EEF2K	Q13131	PRKAA1	S377	S377L	377	Missense	central	0	yes	58.008	0.000	EPSD	COSMIC	56.683	Loss
CAMK_CAMKL_AMPK_PRKAA1_ST	O00418	EEF2K	Q13131	PRKAA1	S377	P375S	375	Missense	proximal	-2	no	58.008	57.460	EPSD	COSMIC	56.683	Down-regulation
CAMK_CAMKL_AMPK_PRKAA1_ST	O00418	EEF2K	Q13131	PRKAA1	S398	S398C	398	Missense	central	0	yes	62.228	0.000	PhosphoSitePlus	COSMIC	56.683	Loss
CAMK_CAMKL_AMPK_PRKAA1_ST	O00418	EEF2K	Q13131	PRKAA1	S398	S399L	399	Missense	proximal	1	no	62.228	61.303	PhosphoSitePlus	COSMIC	56.683	Down-regulation
CAMK_CAMKL_AMPK_PRKAA1_ST	O00418	EEF2K	Q13131	PRKAA1	S398	P394L	394	Missense	distal	-4	no	62.228	61.976	PhosphoSitePlus	COSMIC;GDSC;CCLE	56.683	Down-regulation
CAMK_CAMKL_AMPK_PRKAA1_ST	O00418	EEF2K	Q13131	PRKAA1	S398	P394S	394	Missense	distal	-4	no	62.228	63.471	PhosphoSitePlus	COSMIC	56.683	Up-regulation
CAMK_CAMKL_AMPK_PRKAA1_ST	O00418	EEF2K	Q13131	PRKAA1	S477	S478F	478	Missense	proximal	1	no	52.886	57.426	EPSD	COSMIC	56.683	Gain
CAMK_CAMKL_AMPK_PRKAA1_ST	O60825	PFKFB2	Q13131	PRKAA1	S13	N20D	20	Missense	distal	7	no	63.551	62.030	EPSD	COSMIC	56.683	Down-regulation
CAMK_CAMKL_AMPK_PRKAA1_ST	O60825	PFKFB2	Q13131	PRKAA1	S13	S7L	7	Missense	distal	-6	no	63.551	63.862	EPSD	COSMIC	56.683	Up-regulation
CAMK_CAMKL_AMPK_PRKAA1_ST	O60825	PFKFB2	Q13131	PRKAA1	S13	N12H	12	Missense	proximal	-1	no	63.551	63.578	EPSD	COSMIC;GDSC;CCLE	56.683	Up-regulation
CAMK_CAMKL_AMPK_PRKAA1_ST	O60825	PFKFB2	Q13131	PRKAA1	T39	P38L	38	Missense	proximal	-1	no	58.724	58.795	EPSD	COSMIC	56.683	Up-regulation
CAMK_CAMKL_AMPK_PRKAA1_ST	O60825	PFKFB2	Q13131	PRKAA1	T39	V42F	42	Missense	distal	3	no	58.724	56.619	EPSD	COSMIC	56.683	Loss
CAMK_CAMKL_AMPK_PRKAA1_ST	O60825	PFKFB2	Q13131	PRKAA1	T39	S32C	32	Missense	distal	-7	no	58.724	56.336	EPSD	COSMIC	56.683	Loss
CAMK_CAMKL_AMPK_PRKAA1_ST	O60825	PFKFB2	Q13131	PRKAA1	T39	M34T	34	Missense	distal	-5	no	58.724	53.228	EPSD	COSMIC	56.683	Loss
CAMK_CAMKL_AMPK_PRKAA1_ST	O60825	PFKFB2	Q13131	PRKAA1	T39	T39I	39	Missense	central	0	yes	58.724	0.000	EPSD	COSMIC	56.683	Loss
CAMK_CAMKL_AMPK_PRKAA1_ST	O60825	PFKFB2	Q13131	PRKAA1	T39	V42I	42	Missense	distal	3	no	58.724	55.450	EPSD	COSMIC	56.683	Loss
CAMK_CAMKL_AMPK_PRKAA1_ST	O60825	PFKFB2	Q13131	PRKAA1	T39	G45D	45	Missense	distal	6	no	58.724	58.653	EPSD	COSMIC	56.683	Down-regulation
CAMK_CAMKL_AMPK_PRKAA1_ST	O60825	PFKFB2	Q13131	PRKAA1	T52	T52A	52	Missense	central	0	yes	59.424	0.000	EPSD	COSMIC	56.683	Loss
CAMK_CAMKL_AMPK_PRKAA1_ST	O60825	PFKFB2	Q13131	PRKAA1	T52	G45D	45	Missense	distal	-7	no	59.424	58.120	EPSD	COSMIC	56.683	Down-regulation
CAMK_CAMKL_AMPK_PRKAA1_ST	O60825	PFKFB2	Q13131	PRKAA1	S174	R181S	181	Missense	distal	7	no	57.927	58.513	EPSD	COSMIC	56.683	Up-regulation
CAMK_CAMKL_AMPK_PRKAA1_ST	O60825	PFKFB2	Q13131	PRKAA1	T458	V460L	460	Missense	proximal	2	no	57.719	56.717	EPSD	COSMIC	56.683	Down-regulation
CAMK_CAMKL_AMPK_PRKAA1_ST	O60825	PFKFB2	Q13131	PRKAA1	T458	F453L	453	Missense	distal	-5	no	57.719	63.243	EPSD	COSMIC;GDSC;CCLE	56.683	Up-regulation
CAMK_CAMKL_AMPK_PRKAA1_ST	O60825	PFKFB2	Q13131	PRKAA1	T458	N451Y	451	Missense	distal	-7	no	57.719	56.671	EPSD	COSMIC	56.683	Loss
CAMK_CAMKL_AMPK_PRKAA1_ST	O60825	PFKFB2	Q13131	PRKAA1	T458	R461S	461	Missense	distal	3	no	57.719	58.369	EPSD	COSMIC	56.683	Up-regulation
CAMK_CAMKL_AMPK_PRKAA1_ST	O60825	PFKFB2	Q13131	PRKAA1	T458	T458P	458	Missense	central	0	yes	57.719	0.000	EPSD	COSMIC	56.683	Loss
CAMK_CAMKL_AMPK_PRKAA1_ST	O60825	PFKFB2	Q13131	PRKAA1	T458	R461C	461	Missense	distal	3	no	57.719	56.538	EPSD	COSMIC;GDSC	56.683	Loss
CAMK_CAMKL_AMPK_PRKAA1_ST	O60825	PFKFB2	Q13131	PRKAA1	S466	V460L	460	Missense	distal	-6	no	70.731	72.224	PhosphoSitePlus	COSMIC	56.683	Up-regulation
CAMK_CAMKL_AMPK_PRKAA1_ST	O60825	PFKFB2	Q13131	PRKAA1	S466	S473L	473	Missense	distal	7	no	70.731	70.773	PhosphoSitePlus	COSMIC;GDSC	56.683	Up-regulation
CAMK_CAMKL_AMPK_PRKAA1_ST	O60825	PFKFB2	Q13131	PRKAA1	S466	R461S	461	Missense	distal	-5	no	70.731	67.726	PhosphoSitePlus	COSMIC	56.683	Down-regulation
CAMK_CAMKL_AMPK_PRKAA1_ST	O60825	PFKFB2	Q13131	PRKAA1	S466	R461C	461	Missense	distal	-5	no	70.731	69.377	PhosphoSitePlus	COSMIC;GDSC	56.683	Down-regulation
CAMK_CAMKL_AMPK_PRKAA1_ST	O60825	PFKFB2	Q13131	PRKAA1	S466	S466F	466	Missense	central	0	yes	70.731	0.000	PhosphoSitePlus	COSMIC	56.683	Loss
CAMK_CAMKL_AMPK_PRKAA1_ST	O60825	PFKFB2	Q13131	PRKAA1	S483	K490N	490	Missense	distal	7	no	60.167	61.941	EPSD	COSMIC	56.683	Up-regulation
CAMK_CAMKL_AMPK_PRKAA1_ST	O60825	PFKFB2	Q13131	PRKAA1	S483	R478P	478	Missense	distal	-5	no	60.167	56.604	EPSD	COSMIC	56.683	Loss
CAMK_CAMKL_AMPK_PRKAA1_ST	O60825	PFKFB2	Q13131	PRKAA1	S493	R496H	496	Missense	distal	3	no	59.079	55.511	EPSD	COSMIC	56.683	Loss
CAMK_CAMKL_AMPK_PRKAA1_ST	O60825	PFKFB2	Q13131	PRKAA1	S493	P491S	491	Missense	proximal	-2	no	59.079	58.531	EPSD	COSMIC	56.683	Down-regulation
CAMK_CAMKL_AMPK_PRKAA1_ST	O60825	PFKFB2	Q13131	PRKAA1	S493	K490N	490	Missense	distal	-3	no	59.079	57.784	EPSD	COSMIC	56.683	Down-regulation
CAMK_CAMKL_AMPK_PRKAA1_ST	O60825	PFKFB2	Q13131	PRKAA1	S493	R496S	496	Missense	distal	3	no	59.079	59.730	EPSD	COSMIC	56.683	Up-regulation
CAMK_CAMKL_AMPK_PRKAA1_ST	O60825	PFKFB2	Q13131	PRKAA1	S493	S493N	493	Missense	central	0	yes	59.079	0.000	EPSD	COSMIC	56.683	Loss
CAMK_CAMKL_AMPK_PRKAA1_ST	P13569	CFTR	Q13131	PRKAA1	S45	S45Y	45	Missense	central	0	yes	60.799	0.000	EPSD	COSMIC	56.683	Loss
CAMK_CAMKL_AMPK_PRKAA1_ST	P13569	CFTR	Q13131	PRKAA1	S45	D44N	44	Missense	proximal	-1	no	60.799	60.759	EPSD	COSMIC	56.683	Down-regulation
CAMK_CAMKL_AMPK_PRKAA1_ST	P13569	CFTR	Q13131	PRKAA1	S45	E51K	51	Missense	distal	6	no	60.799	60.571	EPSD	COSMIC	56.683	Down-regulation
CAMK_CAMKL_AMPK_PRKAA1_ST	P13569	CFTR	Q13131	PRKAA1	S45	Q39R	39	Missense	distal	-6	no	60.799	60.441	EPSD	COSMIC	56.683	Down-regulation
CAMK_CAMKL_AMPK_PRKAA1_ST	P13569	CFTR	Q13131	PRKAA1	S256	D249N	249	Missense	distal	-7	no	56.867	56.661	EPSD	COSMIC	56.683	Loss
CAMK_CAMKL_AMPK_PRKAA1_ST	P13569	CFTR	Q13131	PRKAA1	S256	R251K	251	Missense	distal	-5	no	56.867	53.778	EPSD	COSMIC	56.683	Loss
CAMK_CAMKL_AMPK_PRKAA1_ST	P13569	CFTR	Q13131	PRKAA1	S466	V470M	470	Missense	distal	4	no	57.751	59.672	EPSD	COSMIC	56.683	Up-regulation
CAMK_CAMKL_AMPK_PRKAA1_ST	P13569	CFTR	Q13131	PRKAA1	S466	G473E	473	Missense	distal	7	no	57.751	57.026	EPSD	COSMIC	56.683	Down-regulation
CAMK_CAMKL_AMPK_PRKAA1_ST	P13569	CFTR	Q13131	PRKAA1	S466	I471M	471	Missense	distal	5	no	57.751	57.643	EPSD	COSMIC;GDSC;CCLE	56.683	Down-regulation
CAMK_CAMKL_AMPK_PRKAA1_ST	P13569	CFTR	Q13131	PRKAA1	S466	S466L	466	Missense	central	0	yes	57.751	0.000	EPSD	COSMIC	56.683	Loss
CAMK_CAMKL_AMPK_PRKAA1_ST	P13569	CFTR	Q13131	PRKAA1	S492	W496L	496	Missense	distal	4	no	54.734	56.965	EPSD	COSMIC	56.683	Gain
CAMK_CAMKL_AMPK_PRKAA1_ST	P13569	CFTR	Q13131	PRKAA1	S686	E681Q	681	Missense	distal	-5	no	67.697	62.457	EPSD	COSMIC	56.683	Down-regulation
CAMK_CAMKL_AMPK_PRKAA1_ST	P13569	CFTR	Q13131	PRKAA1	S686	Q685K	685	Missense	proximal	-1	no	67.697	67.596	EPSD	COSMIC	56.683	Down-regulation
CAMK_CAMKL_AMPK_PRKAA1_ST	P13569	CFTR	Q13131	PRKAA1	S700	G694R	694	Missense	distal	-6	no	55.869	56.833	EPSD	COSMIC	56.683	Gain
CAMK_CAMKL_AMPK_PRKAA1_ST	P13569	CFTR	Q13131	PRKAA1	S737	E743K	743	Missense	distal	6	no	61.506	61.278	PhosphoSitePlus;EPSD	COSMIC	56.683	Down-regulation
CAMK_CAMKL_AMPK_PRKAA1_ST	P13569	CFTR	Q13131	PRKAA1	S768	R765M	765	Missense	distal	-3	no	65.934	53.052	EPSD;PhosphoSitePlus	COSMIC	56.683	Loss
CAMK_CAMKL_AMPK_PRKAA1_ST	P13569	CFTR	Q13131	PRKAA1	S768	H775Y	775	Missense	distal	7	no	65.934	67.496	EPSD;PhosphoSitePlus	COSMIC	56.683	Up-regulation
CAMK_CAMKL_AMPK_PRKAA1_ST	P13569	CFTR	Q13131	PRKAA1	S813	L812F	812	Missense	proximal	-1	no	62.646	62.574	EPSD;PhosphoSitePlus	COSMIC	56.683	Down-regulation
CAMK_CAMKL_AMPK_PRKAA1_ST	P13569	CFTR	Q13131	PRKAA1	S813	R810E	810	Missense	distal	-3	no	62.646	54.164	EPSD;PhosphoSitePlus	COSMIC	56.683	Loss
CAMK_CAMKL_AMPK_PRKAA1_ST	P13569	CFTR	Q13131	PRKAA1	S813	D806N	806	Missense	distal	-7	no	62.646	62.440	EPSD;PhosphoSitePlus	COSMIC	56.683	Down-regulation
CAMK_CAMKL_AMPK_PRKAA1_ST	P13569	CFTR	Q13131	PRKAA1	S813	E819K	819	Missense	distal	6	no	62.646	62.418	EPSD;PhosphoSitePlus	COSMIC	56.683	Down-regulation
CAMK_CAMKL_AMPK_PRKAA1_ST	P13569	CFTR	Q13131	PRKAA1	S1248	S1248L	1248	Missense	central	0	yes	65.680	0.000	EPSD	COSMIC	56.683	Loss
CAMK_CAMKL_AMPK_PRKAA1_ST	P13569	CFTR	Q13131	PRKAA1	S1455	K1461N	1461	Missense	distal	6	no	60.208	60.145	EPSD	COSMIC	56.683	Down-regulation
CAMK_CAMKL_AMPK_PRKAA1_ST	P13569	CFTR	Q13131	PRKAA1	S1455	P1451L	1451	Missense	distal	-4	no	60.208	59.956	EPSD	COSMIC	56.683	Down-regulation
CAMK_CAMKL_AMPK_PRKAA1_ST	P13569	CFTR	Q13131	PRKAA1	S1456	P1451L	1451	Missense	distal	-5	no	55.860	60.600	EPSD	COSMIC	56.683	Gain
CAMK_CAMKL_AMPK_PRKAA1_ST	P22460	KCNA5	Q13131	PRKAA1	S557	F563L	563	Missense	distal	6	no	59.359	59.227	EPSD	COSMIC	56.683	Down-regulation
CAMK_CAMKL_AMPK_PRKAA1_ST	P22460	KCNA5	Q13131	PRKAA1	S557	Q553H	553	Missense	distal	-4	no	59.359	57.441	EPSD	COSMIC	56.683	Down-regulation
CAMK_CAMKL_AMPK_PRKAA1_ST	P22460	KCNA5	Q13131	PRKAA1	S575	L570P	570	Missense	distal	-5	no	65.857	61.116	EPSD	COSMIC	56.683	Down-regulation
CAMK_CAMKL_AMPK_PRKAA1_ST	P22460	KCNA5	Q13131	PRKAA1	S575	E571K	571	Missense	distal	-4	no	65.857	62.731	EPSD	COSMIC	56.683	Down-regulation
CAMK_CAMKL_AMPK_PRKAA1_ST	P22460	KCNA5	Q13131	PRKAA1	S575	R577L	577	Missense	proximal	2	no	65.857	65.707	EPSD	COSMIC	56.683	Down-regulation
CAMK_CAMKL_AMPK_PRKAA1_ST	O43524	FOXO3	Q13131	PRKAA1	S30	R29L	29	Missense	proximal	-1	no	62.267	62.325	EPSD;PhosphoSitePlus	COSMIC	56.683	Up-regulation
CAMK_CAMKL_AMPK_PRKAA1_ST	O43524	FOXO3	Q13131	PRKAA1	T32	R29L	29	Missense	distal	-3	no	60.858	50.891	EPSD	COSMIC	56.683	Loss
CAMK_CAMKL_AMPK_PRKAA1_ST	O43524	FOXO3	Q13131	PRKAA1	S75	M77L	77	Missense	proximal	2	no	56.886	56.736	EPSD	COSMIC	56.683	Down-regulation
CAMK_CAMKL_AMPK_PRKAA1_ST	O43524	FOXO3	Q13131	PRKAA1	S161	R154Q	154	Missense	distal	-7	no	58.083	58.259	EPSD	COSMIC;GDSC;CCLE	56.683	Up-regulation
CAMK_CAMKL_AMPK_PRKAA1_ST	O43524	FOXO3	Q13131	PRKAA1	T179	P174S	174	Missense	distal	-5	no	61.281	61.839	EPSD;PhosphoSitePlus	COSMIC	56.683	Up-regulation
CAMK_CAMKL_AMPK_PRKAA1_ST	O43524	FOXO3	Q13131	PRKAA1	T179	E185K	185	Missense	distal	6	no	61.281	61.053	EPSD;PhosphoSitePlus	COSMIC	56.683	Down-regulation
CAMK_CAMKL_AMPK_PRKAA1_ST	O43524	FOXO3	Q13131	PRKAA1	S215	L216Q	216	Missense	proximal	1	no	61.885	60.944	EPSD	COSMIC	56.683	Down-regulation
CAMK_CAMKL_AMPK_PRKAA1_ST	O43524	FOXO3	Q13131	PRKAA1	S215	I210S	210	Missense	distal	-5	no	61.885	57.124	EPSD	COSMIC	56.683	Down-regulation
CAMK_CAMKL_AMPK_PRKAA1_ST	O43524	FOXO3	Q13131	PRKAA1	S253	S253F	253	Missense	central	0	yes	63.963	0.000	EPSD	COSMIC	56.683	Loss
CAMK_CAMKL_AMPK_PRKAA1_ST	O43524	FOXO3	Q13131	PRKAA1	S253	R248W	248	Missense	distal	-5	no	63.963	58.770	EPSD	COSMIC	56.683	Down-regulation
CAMK_CAMKL_AMPK_PRKAA1_ST	O43524	FOXO3	Q13131	PRKAA1	T313	S318C	318	Missense	distal	5	no	69.035	69.070	EPSD	COSMIC	56.683	Up-regulation
CAMK_CAMKL_AMPK_PRKAA1_ST	O43524	FOXO3	Q13131	PRKAA1	S357	P361L	361	Missense	distal	4	no	50.651	57.390	EPSD	COSMIC;GDSC;CCLE	56.683	Gain
CAMK_CAMKL_AMPK_PRKAA1_ST	O43524	FOXO3	Q13131	PRKAA1	S359	P361L	361	Missense	proximal	2	no	57.355	56.755	EPSD	COSMIC;GDSC;CCLE	56.683	Down-regulation
CAMK_CAMKL_AMPK_PRKAA1_ST	O43524	FOXO3	Q13131	PRKAA1	S359	T363A	363	Missense	distal	4	no	57.355	59.923	EPSD	COSMIC;GDSC;CCLE	56.683	Up-regulation
CAMK_CAMKL_AMPK_PRKAA1_ST	O43524	FOXO3	Q13131	PRKAA1	S399	P397R	397	Missense	proximal	-2	no	57.857	56.068	EPSD;PhosphoSitePlus	COSMIC	56.683	Loss
CAMK_CAMKL_AMPK_PRKAA1_ST	O43524	FOXO3	Q13131	PRKAA1	S413	F414Y	414	Missense	proximal	1	no	72.932	70.709	EPSD;PhosphoSitePlus	COSMIC	56.683	Down-regulation
CAMK_CAMKL_AMPK_PRKAA1_ST	O43524	FOXO3	Q13131	PRKAA1	S564	M557R	557	Missense	distal	-7	no	61.248	59.825	EPSD	COSMIC	56.683	Down-regulation
CAMK_CAMKL_AMPK_PRKAA1_ST	O43524	FOXO3	Q13131	PRKAA1	S588	T582P	582	Missense	distal	-6	no	64.752	64.636	EPSD;PhosphoSitePlus	COSMIC	56.683	Down-regulation
CAMK_CAMKL_AMPK_PRKAA1_ST	P46527	CDKN1B	Q13131	PRKAA1	S83	R90K	90	Missense	distal	7	no	58.576	57.689	EPSD	COSMIC	56.683	Down-regulation
CAMK_CAMKL_AMPK_PRKAA1_ST	P46527	CDKN1B	Q13131	PRKAA1	S83	E80Q	80	Missense	distal	-3	no	58.576	59.114	EPSD	COSMIC	56.683	Up-regulation
CAMK_CAMKL_AMPK_PRKAA1_ST	P46527	CDKN1B	Q13131	PRKAA1	S83	W76G	76	Missense	distal	-7	no	58.576	58.193	EPSD	COSMIC	56.683	Down-regulation
CAMK_CAMKL_AMPK_PRKAA1_ST	P46527	CDKN1B	Q13131	PRKAA1	S83	Y88C	88	Missense	distal	5	no	58.576	58.523	EPSD	COSMIC	56.683	Down-regulation
CAMK_CAMKL_AMPK_PRKAA1_ST	P46527	CDKN1B	Q13131	PRKAA1	S110	Q107R	107	Missense	distal	-3	no	56.289	64.234	EPSD	COSMIC	56.683	Gain
CAMK_CAMKL_AMPK_PRKAA1_ST	P46527	CDKN1B	Q13131	PRKAA1	S110	D108N	108	Missense	proximal	-2	no	56.289	57.341	EPSD	COSMIC	56.683	Gain
CAMK_CAMKL_AMPK_PRKAA1_ST	P46527	CDKN1B	Q13131	PRKAA1	S140	P133T	133	Missense	distal	-7	no	63.949	64.363	EPSD	COSMIC	56.683	Up-regulation
CAMK_CAMKL_AMPK_PRKAA1_ST	P46527	CDKN1B	Q13131	PRKAA1	S140	P137S	137	Missense	distal	-3	no	63.949	63.413	EPSD	COSMIC	56.683	Down-regulation
CAMK_CAMKL_AMPK_PRKAA1_ST	P46527	CDKN1B	Q13131	PRKAA1	S140	S140R	140	Missense	central	0	yes	63.949	0.000	EPSD	COSMIC	56.683	Loss
CAMK_CAMKL_AMPK_PRKAA1_ST	P46527	CDKN1B	Q13131	PRKAA1	S140	D136G	136	Missense	distal	-4	no	63.949	60.435	EPSD	COSMIC;GDSC	56.683	Down-regulation
CAMK_CAMKL_AMPK_PRKAA1_ST	P46527	CDKN1B	Q13131	PRKAA1	S140	E146V	146	Missense	distal	6	no	63.949	63.664	EPSD	COSMIC	56.683	Down-regulation
CAMK_CAMKL_AMPK_PRKAA1_ST	P46527	CDKN1B	Q13131	PRKAA1	T157	A156V	156	Missense	proximal	-1	no	57.685	57.593	EPSD	COSMIC	56.683	Down-regulation
CAMK_CAMKL_AMPK_PRKAA1_ST	P46527	CDKN1B	Q13131	PRKAA1	T157	D158Y	158	Missense	proximal	1	no	57.685	60.841	EPSD	COSMIC	56.683	Up-regulation
CAMK_CAMKL_AMPK_PRKAA1_ST	P46527	CDKN1B	Q13131	PRKAA1	T157	T157N	157	Missense	central	0	yes	57.685	0.000	EPSD	COSMIC	56.683	Loss
CAMK_CAMKL_AMPK_PRKAA1_ST	P46527	CDKN1B	Q13131	PRKAA1	T157	D159Y	159	Missense	proximal	2	no	57.685	56.575	EPSD	COSMIC	56.683	Loss
CAMK_CAMKL_AMPK_PRKAA1_ST	P46527	CDKN1B	Q13131	PRKAA1	T157	S161F	161	Missense	distal	4	no	57.685	60.078	EPSD	COSMIC	56.683	Up-regulation
CAMK_CAMKL_AMPK_PRKAA1_ST	P46527	CDKN1B	Q13131	PRKAA1	S175	R169K	169	Missense	distal	-6	no	59.348	57.867	EPSD	COSMIC	56.683	Down-regulation
CAMK_CAMKL_AMPK_PRKAA1_ST	P46527	CDKN1B	Q13131	PRKAA1	S175	N168K	168	Missense	distal	-7	no	59.348	61.047	EPSD	COSMIC	56.683	Up-regulation
CAMK_CAMKL_AMPK_PRKAA1_ST	P46527	CDKN1B	Q13131	PRKAA1	S175	G182D	182	Missense	distal	7	no	59.348	58.179	EPSD	COSMIC	56.683	Down-regulation
CAMK_CAMKL_AMPK_PRKAA1_ST	P08151	GLI1	Q13131	PRKAA1	S69	P66R	66	Missense	distal	-3	no	51.382	60.242	EPSD	COSMIC	56.683	Gain
CAMK_CAMKL_AMPK_PRKAA1_ST	P08151	GLI1	Q13131	PRKAA1	S69	G65C	65	Missense	distal	-4	no	51.382	59.301	EPSD	COSMIC	56.683	Gain
CAMK_CAMKL_AMPK_PRKAA1_ST	P08151	GLI1	Q13131	PRKAA1	S84	S84F	84	Missense	central	0	yes	60.430	0.000	EPSD	COSMIC	56.683	Loss
CAMK_CAMKL_AMPK_PRKAA1_ST	P08151	GLI1	Q13131	PRKAA1	S84	L88M	88	Missense	distal	4	no	60.430	57.854	EPSD	COSMIC	56.683	Down-regulation
CAMK_CAMKL_AMPK_PRKAA1_ST	P08151	GLI1	Q13131	PRKAA1	S89	S84F	84	Missense	distal	-5	no	60.189	58.847	EPSD	COSMIC	56.683	Down-regulation
CAMK_CAMKL_AMPK_PRKAA1_ST	P08151	GLI1	Q13131	PRKAA1	S89	S92N	92	Missense	distal	3	no	60.189	62.183	EPSD	COSMIC	56.683	Up-regulation
CAMK_CAMKL_AMPK_PRKAA1_ST	P08151	GLI1	Q13131	PRKAA1	S89	L88M	88	Missense	proximal	-1	no	60.189	60.181	EPSD	COSMIC	56.683	Down-regulation
CAMK_CAMKL_AMPK_PRKAA1_ST	P08151	GLI1	Q13131	PRKAA1	S89	L95M	95	Missense	distal	6	no	60.189	60.163	EPSD	COSMIC	56.683	Down-regulation
CAMK_CAMKL_AMPK_PRKAA1_ST	P08151	GLI1	Q13131	PRKAA1	S204	L211M	211	Missense	distal	7	no	57.771	55.767	EPSD	COSMIC	56.683	Loss
CAMK_CAMKL_AMPK_PRKAA1_ST	P08151	GLI1	Q13131	PRKAA1	S204	P210A	210	Missense	distal	6	no	57.771	57.880	EPSD	COSMIC	56.683	Up-regulation
CAMK_CAMKL_AMPK_PRKAA1_ST	P08151	GLI1	Q13131	PRKAA1	S204	M199V	199	Missense	distal	-5	no	57.771	53.074	EPSD	COSMIC	56.683	Loss
CAMK_CAMKL_AMPK_PRKAA1_ST	P08151	GLI1	Q13131	PRKAA1	S204	Q208L	208	Missense	distal	4	no	57.771	67.336	EPSD	COSMIC;GDSC	56.683	Up-regulation
CAMK_CAMKL_AMPK_PRKAA1_ST	P08151	GLI1	Q13131	PRKAA1	S204	D198Y	198	Missense	distal	-6	no	57.771	52.887	EPSD	COSMIC	56.683	Loss
CAMK_CAMKL_AMPK_PRKAA1_ST	P08151	GLI1	Q13131	PRKAA1	S204	Q208R	208	Missense	distal	4	no	57.771	61.854	EPSD	COSMIC	56.683	Up-regulation
CAMK_CAMKL_AMPK_PRKAA1_ST	P08151	GLI1	Q13131	PRKAA1	S204	G197A	197	Missense	distal	-7	no	57.771	54.648	EPSD	COSMIC	56.683	Loss
CAMK_CAMKL_AMPK_PRKAA1_ST	P08151	GLI1	Q13131	PRKAA1	S378	D375N	375	Missense	distal	-3	no	53.127	57.044	EPSD	COSMIC	56.683	Gain
CAMK_CAMKL_AMPK_PRKAA1_ST	P08151	GLI1	Q13131	PRKAA1	S408	S410C	410	Missense	proximal	2	no	63.799	62.502	PhosphoSitePlus	COSMIC	56.683	Down-regulation
CAMK_CAMKL_AMPK_PRKAA1_ST	P08151	GLI1	Q13131	PRKAA1	S408	P407S	407	Missense	proximal	-1	no	63.799	63.844	PhosphoSitePlus	COSMIC	56.683	Up-regulation
CAMK_CAMKL_AMPK_PRKAA1_ST	P08151	GLI1	Q13131	PRKAA1	S408	S408P	408	Missense	central	0	yes	63.799	0.000	PhosphoSitePlus	COSMIC	56.683	Loss
CAMK_CAMKL_AMPK_PRKAA1_ST	P08151	GLI1	Q13131	PRKAA1	S408	P414S	414	Missense	distal	6	no	63.799	63.814	PhosphoSitePlus	COSMIC	56.683	Up-regulation
CAMK_CAMKL_AMPK_PRKAA1_ST	P08151	GLI1	Q13131	PRKAA1	S408	R405Q	405	Missense	distal	-3	no	63.799	55.854	PhosphoSitePlus	COSMIC	56.683	Loss
CAMK_CAMKL_AMPK_PRKAA1_ST	P08151	GLI1	Q13131	PRKAA1	S408	P414L	414	Missense	distal	6	no	63.799	63.947	PhosphoSitePlus	COSMIC	56.683	Up-regulation
CAMK_CAMKL_AMPK_PRKAA1_ST	P08151	GLI1	Q13131	PRKAA1	S408	K415Q	415	Missense	distal	7	no	63.799	66.050	PhosphoSitePlus	COSMIC	56.683	Up-regulation
CAMK_CAMKL_AMPK_PRKAA1_ST	P08151	GLI1	Q13131	PRKAA1	S410	P414L	414	Missense	distal	4	no	52.625	59.364	EPSD	COSMIC	56.683	Gain
CAMK_CAMKL_AMPK_PRKAA1_ST	P08151	GLI1	Q13131	PRKAA1	S538	S538C	538	Missense	central	0	yes	58.830	0.000	EPSD	COSMIC	56.683	Loss
CAMK_CAMKL_AMPK_PRKAA1_ST	P08151	GLI1	Q13131	PRKAA1	S538	G534A	534	Missense	distal	-4	no	58.830	60.974	EPSD	COSMIC	56.683	Up-regulation
CAMK_CAMKL_AMPK_PRKAA1_ST	P08151	GLI1	Q13131	PRKAA1	S538	R541C	541	Missense	distal	3	no	58.830	57.650	EPSD	COSMIC;GDSC;CCLE	56.683	Down-regulation
CAMK_CAMKL_AMPK_PRKAA1_ST	P08151	GLI1	Q13131	PRKAA1	S538	V533M	533	Missense	distal	-5	no	58.830	63.527	EPSD	COSMIC	56.683	Up-regulation
CAMK_CAMKL_AMPK_PRKAA1_ST	P08151	GLI1	Q13131	PRKAA1	S538	P535S	535	Missense	distal	-3	no	58.830	58.295	EPSD	COSMIC;GDSC	56.683	Down-regulation
CAMK_CAMKL_AMPK_PRKAA1_ST	P08151	GLI1	Q13131	PRKAA1	S545	S538C	538	Missense	distal	-7	no	73.952	71.564	EPSD	COSMIC	56.683	Down-regulation
CAMK_CAMKL_AMPK_PRKAA1_ST	P08151	GLI1	Q13131	PRKAA1	S545	R541C	541	Missense	distal	-4	no	73.952	78.263	EPSD	COSMIC;GDSC;CCLE	56.683	Up-regulation
CAMK_CAMKL_AMPK_PRKAA1_ST	P08151	GLI1	Q13131	PRKAA1	S545	S550G	550	Missense	distal	5	no	73.952	73.907	EPSD	COSMIC	56.683	Down-regulation
CAMK_CAMKL_AMPK_PRKAA1_ST	P08151	GLI1	Q13131	PRKAA1	S545	S548N	548	Missense	distal	3	no	73.952	75.946	EPSD	COSMIC	56.683	Up-regulation
CAMK_CAMKL_AMPK_PRKAA1_ST	P08151	GLI1	Q13131	PRKAA1	S560	R558H	558	Missense	proximal	-2	no	59.832	57.111	EPSD	COSMIC	56.683	Down-regulation
CAMK_CAMKL_AMPK_PRKAA1_ST	P08151	GLI1	Q13131	PRKAA1	S560	R557G	557	Missense	distal	-3	no	59.832	50.797	EPSD	COSMIC	56.683	Loss
CAMK_CAMKL_AMPK_PRKAA1_ST	P08151	GLI1	Q13131	PRKAA1	S560	R557H	557	Missense	distal	-3	no	59.832	51.976	EPSD	COSMIC	56.683	Loss
CAMK_CAMKL_AMPK_PRKAA1_ST	P08151	GLI1	Q13131	PRKAA1	S560	P566S	566	Missense	distal	6	no	59.832	59.847	EPSD	COSMIC	56.683	Up-regulation
CAMK_CAMKL_AMPK_PRKAA1_ST	P08151	GLI1	Q13131	PRKAA1	S560	P566L	566	Missense	distal	6	no	59.832	59.981	EPSD	COSMIC	56.683	Up-regulation
CAMK_CAMKL_AMPK_PRKAA1_ST	P08151	GLI1	Q13131	PRKAA1	S560	L561M	561	Missense	proximal	1	no	59.832	62.800	EPSD	COSMIC	56.683	Up-regulation
CAMK_CAMKL_AMPK_PRKAA1_ST	P08151	GLI1	Q13131	PRKAA1	S560	R558L	558	Missense	proximal	-2	no	59.832	58.646	EPSD	COSMIC	56.683	Down-regulation
CAMK_CAMKL_AMPK_PRKAA1_ST	P08151	GLI1	Q13131	PRKAA1	S934	L931R	931	Missense	distal	-3	no	55.143	65.109	EPSD	COSMIC	56.683	Gain
CAMK_CAMKL_AMPK_PRKAA1_ST	P08151	GLI1	Q13131	PRKAA1	S934	G932E	932	Missense	proximal	-2	no	55.143	57.311	EPSD	COSMIC;CCLE	56.683	Gain
CAMK_CAMKL_AMPK_PRKAA1_ST	P08151	GLI1	Q13131	PRKAA1	S939	R940Q	940	Missense	proximal	1	no	56.934	56.054	EPSD	COSMIC	56.683	Loss
CAMK_CAMKL_AMPK_PRKAA1_ST	P08151	GLI1	Q13131	PRKAA1	S939	R940W	940	Missense	proximal	1	no	56.934	57.539	EPSD	COSMIC	56.683	Up-regulation
CAMK_CAMKL_AMPK_PRKAA1_ST	P08151	GLI1	Q13131	PRKAA1	S939	G933D	933	Missense	distal	-6	no	56.934	59.813	EPSD	COSMIC	56.683	Up-regulation
CAMK_CAMKL_AMPK_PRKAA1_ST	P08151	GLI1	Q13131	PRKAA1	S939	G932E	932	Missense	distal	-7	no	56.934	55.729	EPSD	COSMIC;CCLE	56.683	Loss
CAMK_CAMKL_AMPK_PRKAA1_ST	P08151	GLI1	Q13131	PRKAA1	S939	R940C	940	Missense	proximal	1	no	56.934	57.259	EPSD	COSMIC	56.683	Up-regulation
CAMK_CAMKL_AMPK_PRKAA1_ST	P08151	GLI1	Q13131	PRKAA1	S939	S934F	934	Missense	distal	-5	no	56.934	55.592	EPSD	COSMIC	56.683	Loss
CAMK_CAMKL_AMPK_PRKAA1_ST	P08151	GLI1	Q13131	PRKAA1	S939	A941T	941	Missense	proximal	2	no	56.934	57.380	EPSD	COSMIC	56.683	Up-regulation
CAMK_CAMKL_AMPK_PRKAA1_ST	P08151	GLI1	Q13131	PRKAA1	S1071	R1068Q	1068	Missense	distal	-3	no	60.079	52.134	EPSD	COSMIC	56.683	Loss
CAMK_CAMKL_AMPK_PRKAA1_ST	P08151	GLI1	Q13131	PRKAA1	S1071	R1068W	1068	Missense	distal	-3	no	60.079	-32.921	EPSD	COSMIC	56.683	Loss
CAMK_CAMKL_AMPK_PRKAA1_ST	P08151	GLI1	Q13131	PRKAA1	S1071	H1065N	1065	Missense	distal	-6	no	60.079	61.262	EPSD	COSMIC	56.683	Up-regulation
CAMK_CAMKL_AMPK_PRKAA1_ST	P08151	GLI1	Q13131	PRKAA1	S1071	S1064P	1064	Missense	distal	-7	no	60.079	57.812	EPSD	COSMIC	56.683	Down-regulation
CAMK_CAMKL_AMPK_PRKAA1_ST	P08151	GLI1	Q13131	PRKAA1	S1071	P1077H	1077	Missense	distal	6	no	60.079	60.093	EPSD	COSMIC	56.683	Up-regulation
CAMK_CAMKL_AMPK_PRKAA1_ST	Q16576	RBBP7	Q13131	PRKAA1	T416	E412A	412	Missense	distal	-4	no	57.678	56.269	EPSD	COSMIC	56.683	Loss
CAMK_CAMKL_AMPK_PRKAA1_ST	Q16576	RBBP7	Q13131	PRKAA1	T416	T416M	416	Missense	central	0	yes	57.678	0.000	EPSD	COSMIC	56.683	Loss
CAMK_CAMKL_AMPK_PRKAA1_ST	P11908	PRPS2	Q13131	PRKAA1	T272	A265T	265	Missense	distal	-7	no	58.767	59.616	EPSD	COSMIC	56.683	Up-regulation
CAMK_CAMKL_AMPK_PRKAA1_ST	P11908	PRPS2	Q13131	PRKAA1	T272	E278Q	278	Missense	distal	6	no	58.767	58.916	EPSD	COSMIC	56.683	Up-regulation
CAMK_CAMKL_AMPK_PRKAA1_ST	P11908	PRPS2	Q13131	PRKAA1	T272	A268S	268	Missense	distal	-4	no	58.767	59.167	EPSD	COSMIC	56.683	Up-regulation
CAMK_CAMKL_AMPK_PRKAA1_ST	P11908	PRPS2	Q13131	PRKAA1	T272	A268T	268	Missense	distal	-4	no	58.767	57.911	EPSD	COSMIC;CCLE	56.683	Down-regulation
CAMK_CAMKL_AMPK_PRKAA1_ST	Q9BZL4	PPP1R12C	Q13131	PRKAA1	S336	G329S	329	Missense	distal	-7	no	61.500	61.081	EPSD	COSMIC	56.683	Down-regulation
CAMK_CAMKL_AMPK_PRKAA1_ST	Q9BZL4	PPP1R12C	Q13131	PRKAA1	S336	S338N	338	Missense	proximal	2	no	61.500	61.256	EPSD	COSMIC	56.683	Down-regulation
CAMK_CAMKL_AMPK_PRKAA1_ST	Q9BZL4	PPP1R12C	Q13131	PRKAA1	S344	S338N	338	Missense	distal	-6	no	61.934	62.055	EPSD	COSMIC	56.683	Up-regulation
CAMK_CAMKL_AMPK_PRKAA1_ST	Q9BZL4	PPP1R12C	Q13131	PRKAA1	S355	S355C	355	Missense	central	0	yes	58.388	0.000	EPSD	COSMIC	56.683	Loss
CAMK_CAMKL_AMPK_PRKAA1_ST	Q9BZL4	PPP1R12C	Q13131	PRKAA1	S355	K353N	353	Missense	proximal	-2	no	58.388	57.589	EPSD	COSMIC	56.683	Down-regulation
CAMK_CAMKL_AMPK_PRKAA1_ST	Q9BZL4	PPP1R12C	Q13131	PRKAA1	S452	S454F	454	Missense	proximal	2	no	66.941	66.648	PhosphoSitePlus	COSMIC	56.683	Down-regulation
CAMK_CAMKL_AMPK_PRKAA1_ST	Q9BZL4	PPP1R12C	Q13131	PRKAA1	S452	Q448K	448	Missense	distal	-4	no	66.941	65.229	PhosphoSitePlus	COSMIC	56.683	Down-regulation
CAMK_CAMKL_AMPK_PRKAA1_ST	Q9BZL4	PPP1R12C	Q13131	PRKAA1	S476	P480L	480	Missense	distal	4	no	51.938	58.678	EPSD	COSMIC;CCLE	56.683	Gain
CAMK_CAMKL_AMPK_PRKAA1_ST	Q9BZL4	PPP1R12C	Q13131	PRKAA1	S486	P480L	480	Missense	distal	-6	no	57.188	57.148	EPSD	COSMIC;CCLE	56.683	Down-regulation
CAMK_CAMKL_AMPK_PRKAA1_ST	Q9BZL4	PPP1R12C	Q13131	PRKAA1	S532	D525N	525	Missense	distal	-7	no	66.150	65.943	EPSD	COSMIC	56.683	Down-regulation
CAMK_CAMKL_AMPK_PRKAA1_ST	Q9BZL4	PPP1R12C	Q13131	PRKAA1	S544	R551L	551	Missense	distal	7	no	57.037	57.665	EPSD	COSMIC	56.683	Up-regulation
CAMK_CAMKL_AMPK_PRKAA1_ST	Q9BZL4	PPP1R12C	Q13131	PRKAA1	S544	R551C	551	Missense	distal	7	no	57.037	57.070	EPSD	COSMIC	56.683	Up-regulation
CAMK_CAMKL_AMPK_PRKAA1_ST	Q9BZL4	PPP1R12C	Q13131	PRKAA1	S559	S559F	559	Missense	central	0	yes	63.273	0.000	EPSD	COSMIC	56.683	Loss
CAMK_CAMKL_AMPK_PRKAA1_ST	Q9BZL4	PPP1R12C	Q13131	PRKAA1	S559	Q561H	561	Missense	proximal	2	no	63.273	64.045	EPSD	COSMIC	56.683	Up-regulation
CAMK_CAMKL_AMPK_PRKAA1_ST	Q9BZL4	PPP1R12C	Q13131	PRKAA1	S757	R760L	760	Missense	distal	3	no	66.004	64.672	EPSD	COSMIC;GDSC;CCLE	56.683	Down-regulation
CAMK_CAMKL_AMPK_PRKAA1_ST	Q6TCH7	PAQR3	Q13131	PRKAA1	T32	P37L	37	Missense	distal	5	no	61.599	61.592	PhosphoSitePlus	COSMIC	56.683	Down-regulation
CAMK_CAMKL_AMPK_PRKAA1_ST	P04637	TP53	Q13131	PRKAA1	T18	P13L	13	Missense	distal	-5	no	54.024	58.764	PhosphoSitePlus;EPSD	COSMIC	56.683	Gain
CAMK_CAMKL_AMPK_PRKAA1_ST	P04637	TP53	Q13131	PRKAA1	S46	M40I	40	Missense	distal	-6	no	58.440	56.607	EPSD	COSMIC	56.683	Loss
CAMK_CAMKL_AMPK_PRKAA1_ST	P04637	TP53	Q13131	PRKAA1	S46	W53C	53	Missense	distal	7	no	58.440	58.248	EPSD	COSMIC	56.683	Down-regulation
CAMK_CAMKL_AMPK_PRKAA1_ST	P04637	TP53	Q13131	PRKAA1	S46	W53G	53	Missense	distal	7	no	58.440	58.751	EPSD	COSMIC	56.683	Up-regulation
CAMK_CAMKL_AMPK_PRKAA1_ST	P04637	TP53	Q13131	PRKAA1	S46	S46F	46	Missense	central	0	yes	58.440	0.000	EPSD	COSMIC	56.683	Loss
CAMK_CAMKL_AMPK_PRKAA1_ST	P04637	TP53	Q13131	PRKAA1	S46	D49Y	49	Missense	distal	3	no	58.440	58.620	EPSD	COSMIC	56.683	Up-regulation
CAMK_CAMKL_AMPK_PRKAA1_ST	P04637	TP53	Q13131	PRKAA1	S46	P47L	47	Missense	proximal	1	no	58.440	58.147	EPSD	COSMIC	56.683	Down-regulation
CAMK_CAMKL_AMPK_PRKAA1_ST	P04637	TP53	Q13131	PRKAA1	S46	D49H	49	Missense	distal	3	no	58.440	53.481	EPSD	COSMIC;GDSC;CCLE	56.683	Loss
CAMK_CAMKL_AMPK_PRKAA1_ST	P04637	TP53	Q13131	PRKAA1	S46	P47S	47	Missense	proximal	1	no	58.440	59.073	EPSD	COSMIC	56.683	Up-regulation
CAMK_CAMKL_AMPK_PRKAA1_ST	P04637	TP53	Q13131	PRKAA1	S46	D41N	41	Missense	distal	-5	no	58.440	44.365	EPSD	COSMIC	56.683	Loss
CAMK_CAMKL_AMPK_PRKAA1_ST	P04637	TP53	Q13131	PRKAA1	S46	D48H	48	Missense	proximal	2	no	58.440	58.187	EPSD	COSMIC	56.683	Down-regulation
CAMK_CAMKL_AMPK_PRKAA1_ST	P04637	TP53	Q13131	PRKAA1	S46	D49N	49	Missense	distal	3	no	58.440	59.694	EPSD	COSMIC	56.683	Up-regulation
CAMK_CAMKL_AMPK_PRKAA1_ST	P04637	TP53	Q13131	PRKAA1	S46	M44I	44	Missense	proximal	-2	no	58.440	58.977	EPSD	COSMIC	56.683	Up-regulation
CAMK_CAMKL_AMPK_PRKAA1_ST	P04637	TP53	Q13131	PRKAA1	S46	Q52H	52	Missense	distal	6	no	58.440	58.116	EPSD	COSMIC	56.683	Down-regulation
CAMK_CAMKL_AMPK_PRKAA1_ST	P04637	TP53	Q13131	PRKAA1	S46	D49V	49	Missense	distal	3	no	58.440	58.597	EPSD	COSMIC	56.683	Up-regulation
CAMK_CAMKL_AMPK_PRKAA1_ST	P04637	TP53	Q13131	PRKAA1	S46	A39V	39	Missense	distal	-7	no	58.440	59.765	EPSD	COSMIC	56.683	Up-regulation
CAMK_CAMKL_AMPK_PRKAA1_ST	P04637	TP53	Q13131	PRKAA1	S46	A39S	39	Missense	distal	-7	no	58.440	61.143	EPSD	COSMIC	56.683	Up-regulation
CAMK_CAMKL_AMPK_PRKAA1_ST	P04637	TP53	Q13131	PRKAA1	S46	D42Y	42	Missense	distal	-4	no	58.440	54.609	EPSD	COSMIC	56.683	Loss
CAMK_CAMKL_AMPK_PRKAA1_ST	P04637	TP53	Q13131	PRKAA1	S46	M44R	44	Missense	proximal	-2	no	58.440	59.614	EPSD	COSMIC	56.683	Up-regulation
CAMK_CAMKL_AMPK_PRKAA1_ST	P04637	TP53	Q13131	PRKAA1	S46	S46P	46	Missense	central	0	yes	58.440	0.000	EPSD	COSMIC	56.683	Loss
CAMK_CAMKL_AMPK_PRKAA1_ST	P04637	TP53	Q13131	PRKAA1	S46	M44V	44	Missense	proximal	-2	no	58.440	60.862	EPSD	COSMIC	56.683	Up-regulation
CAMK_CAMKL_AMPK_PRKAA1_ST	P04637	TP53	Q13131	PRKAA1	S46	L45P	45	Missense	proximal	-1	no	58.440	58.370	EPSD	COSMIC	56.683	Down-regulation
CAMK_CAMKL_AMPK_PRKAA1_ST	P04637	TP53	Q13131	PRKAA1	S46	M44T	44	Missense	proximal	-2	no	58.440	58.171	EPSD	COSMIC	56.683	Down-regulation
CAMK_CAMKL_AMPK_PRKAA1_ST	P04637	TP53	Q13131	PRKAA1	S46	A39T	39	Missense	distal	-7	no	58.440	59.290	EPSD	COSMIC	56.683	Up-regulation
CAMK_CAMKL_AMPK_PRKAA1_ST	P04637	TP53	Q13131	PRKAA1	S46	L43F	43	Missense	distal	-3	no	58.440	59.160	EPSD	COSMIC	56.683	Up-regulation
CAMK_CAMKL_AMPK_PRKAA1_ST	P04637	TP53	Q13131	PRKAA1	S46	D41H	41	Missense	distal	-5	no	58.440	56.918	EPSD	COSMIC	56.683	Down-regulation
CAMK_CAMKL_AMPK_PRKAA1_ST	P04637	TP53	Q13131	PRKAA1	S46	D49E	49	Missense	distal	3	no	58.440	56.731	EPSD	COSMIC	56.683	Down-regulation
CAMK_CAMKL_AMPK_PRKAA1_ST	P04637	TP53	Q13131	PRKAA1	S46	D49G	49	Missense	distal	3	no	58.440	58.902	EPSD	COSMIC	56.683	Up-regulation
CAMK_CAMKL_AMPK_PRKAA1_ST	P04637	TP53	Q13131	PRKAA1	S46	D48A	48	Missense	proximal	2	no	58.440	57.597	EPSD	COSMIC	56.683	Down-regulation
CAMK_CAMKL_AMPK_PRKAA1_ST	P04637	TP53	Q13131	PRKAA1	S46	D48Y	48	Missense	proximal	2	no	58.440	57.331	EPSD	COSMIC	56.683	Down-regulation
CAMK_CAMKL_AMPK_PRKAA1_ST	P04637	TP53	Q13131	PRKAA1	S46	D48E	48	Missense	proximal	2	no	58.440	58.401	EPSD	COSMIC	56.683	Down-regulation
CAMK_CAMKL_AMPK_PRKAA1_ST	P04637	TP53	Q13131	PRKAA1	S46	D49I	49	Missense	distal	3	no	58.440	55.323	EPSD	COSMIC	56.683	Loss
CAMK_CAMKL_AMPK_PRKAA1_ST	P04637	TP53	Q13131	PRKAA1	S46	D41E	41	Missense	distal	-5	no	58.440	61.856	EPSD	COSMIC	56.683	Up-regulation
CAMK_CAMKL_AMPK_PRKAA1_ST	P04637	TP53	Q13131	PRKAA1	S99	S94L	94	Missense	distal	-5	no	54.806	58.988	EPSD	COSMIC	56.683	Gain
CAMK_CAMKL_AMPK_PRKAA1_ST	P04637	TP53	Q13131	PRKAA1	S106	G108C	108	Missense	proximal	2	no	57.242	56.455	EPSD	COSMIC	56.683	Loss
CAMK_CAMKL_AMPK_PRKAA1_ST	P04637	TP53	Q13131	PRKAA1	S106	S99F	99	Missense	distal	-7	no	57.242	54.650	EPSD	COSMIC	56.683	Loss
CAMK_CAMKL_AMPK_PRKAA1_ST	P04637	TP53	Q13131	PRKAA1	S106	R110H	110	Missense	distal	4	no	57.242	54.241	EPSD	COSMIC	56.683	Loss
CAMK_CAMKL_AMPK_PRKAA1_ST	P04637	TP53	Q13131	PRKAA1	S106	Y107Q	107	Missense	proximal	1	no	57.242	53.059	EPSD	COSMIC	56.683	Loss
CAMK_CAMKL_AMPK_PRKAA1_ST	P04637	TP53	Q13131	PRKAA1	S106	T102I	102	Missense	distal	-4	no	57.242	55.699	EPSD	COSMIC	56.683	Loss
CAMK_CAMKL_AMPK_PRKAA1_ST	P04637	TP53	Q13131	PRKAA1	S106	K101R	101	Missense	distal	-5	no	57.242	60.332	EPSD	COSMIC	56.683	Up-regulation
CAMK_CAMKL_AMPK_PRKAA1_ST	P04637	TP53	Q13131	PRKAA1	S106	Y107C	107	Missense	proximal	1	no	57.242	54.263	EPSD	COSMIC	56.683	Loss
CAMK_CAMKL_AMPK_PRKAA1_ST	P04637	TP53	Q13131	PRKAA1	S106	S106I	106	Missense	central	0	yes	57.242	0.000	EPSD	COSMIC	56.683	Loss
CAMK_CAMKL_AMPK_PRKAA1_ST	P04637	TP53	Q13131	PRKAA1	S106	Y107H	107	Missense	proximal	1	no	57.242	56.937	EPSD	COSMIC	56.683	Down-regulation
CAMK_CAMKL_AMPK_PRKAA1_ST	P04637	TP53	Q13131	PRKAA1	S106	T102P	102	Missense	distal	-4	no	57.242	57.255	EPSD	COSMIC	56.683	Up-regulation
CAMK_CAMKL_AMPK_PRKAA1_ST	P04637	TP53	Q13131	PRKAA1	S106	L111M	111	Missense	distal	5	no	57.242	57.065	EPSD	COSMIC	56.683	Down-regulation
CAMK_CAMKL_AMPK_PRKAA1_ST	P04637	TP53	Q13131	PRKAA1	S106	F109I	109	Missense	distal	3	no	57.242	56.073	EPSD	COSMIC	56.683	Loss
CAMK_CAMKL_AMPK_PRKAA1_ST	P04637	TP53	Q13131	PRKAA1	S106	G108D	108	Missense	proximal	2	no	57.242	58.394	EPSD	COSMIC	56.683	Up-regulation
CAMK_CAMKL_AMPK_PRKAA1_ST	P04637	TP53	Q13131	PRKAA1	S106	S99P	99	Missense	distal	-7	no	57.242	54.975	EPSD	COSMIC	56.683	Loss
CAMK_CAMKL_AMPK_PRKAA1_ST	P04637	TP53	Q13131	PRKAA1	S106	Q104H	104	Missense	proximal	-2	no	57.242	54.059	EPSD	COSMIC	56.683	Loss
CAMK_CAMKL_AMPK_PRKAA1_ST	P04637	TP53	Q13131	PRKAA1	S106	K101N	101	Missense	distal	-5	no	57.242	42.399	EPSD	COSMIC	56.683	Loss
CAMK_CAMKL_AMPK_PRKAA1_ST	P04637	TP53	Q13131	PRKAA1	S106	Q104L	104	Missense	proximal	-2	no	57.242	55.594	EPSD	COSMIC	56.683	Loss
CAMK_CAMKL_AMPK_PRKAA1_ST	P04637	TP53	Q13131	PRKAA1	S106	R110S	110	Missense	distal	4	no	57.242	56.136	EPSD	COSMIC	56.683	Loss
CAMK_CAMKL_AMPK_PRKAA1_ST	P04637	TP53	Q13131	PRKAA1	S106	G112E	112	Missense	distal	6	no	57.242	57.644	EPSD	COSMIC	56.683	Up-regulation
CAMK_CAMKL_AMPK_PRKAA1_ST	P04637	TP53	Q13131	PRKAA1	S106	G112C	112	Missense	distal	6	no	57.242	57.695	EPSD	COSMIC	56.683	Up-regulation
CAMK_CAMKL_AMPK_PRKAA1_ST	P04637	TP53	Q13131	PRKAA1	S106	G112S	112	Missense	distal	6	no	57.242	57.471	EPSD	COSMIC	56.683	Up-regulation
CAMK_CAMKL_AMPK_PRKAA1_ST	P04637	TP53	Q13131	PRKAA1	S106	G112V	112	Missense	distal	6	no	57.242	57.360	EPSD	COSMIC	56.683	Up-regulation
CAMK_CAMKL_AMPK_PRKAA1_ST	P04637	TP53	Q13131	PRKAA1	S106	G112D	112	Missense	distal	6	no	57.242	57.171	EPSD	COSMIC	56.683	Down-regulation
CAMK_CAMKL_AMPK_PRKAA1_ST	P04637	TP53	Q13131	PRKAA1	S106	G112R	112	Missense	distal	6	no	57.242	57.364	EPSD	COSMIC	56.683	Up-regulation
CAMK_CAMKL_AMPK_PRKAA1_ST	P04637	TP53	Q13131	PRKAA1	S106	G112A	112	Missense	distal	6	no	57.242	57.565	EPSD	COSMIC	56.683	Up-regulation
CAMK_CAMKL_AMPK_PRKAA1_ST	P04637	TP53	Q13131	PRKAA1	S106	G112F	112	Missense	distal	6	no	57.242	57.736	EPSD	COSMIC	56.683	Up-regulation
CAMK_CAMKL_AMPK_PRKAA1_ST	P04637	TP53	Q13131	PRKAA1	S106	F113S	113	Missense	distal	7	no	57.242	58.510	EPSD	COSMIC;CCLE	56.683	Up-regulation
CAMK_CAMKL_AMPK_PRKAA1_ST	P04637	TP53	Q13131	PRKAA1	S106	F113P	113	Missense	distal	7	no	57.242	58.012	EPSD	COSMIC	56.683	Up-regulation
CAMK_CAMKL_AMPK_PRKAA1_ST	P04637	TP53	Q13131	PRKAA1	T155	T150I	150	Missense	distal	-5	no	51.338	57.580	EPSD	COSMIC	56.683	Gain
CAMK_CAMKL_AMPK_PRKAA1_ST	P04637	TP53	Q13131	PRKAA1	S269	A276S	276	Missense	distal	7	no	57.267	57.139	EPSD	COSMIC	56.683	Down-regulation
CAMK_CAMKL_AMPK_PRKAA1_ST	P04637	TP53	Q13131	PRKAA1	S269	G262H	262	Missense	distal	-7	no	57.267	52.828	EPSD	COSMIC	56.683	Loss
CAMK_CAMKL_AMPK_PRKAA1_ST	P04637	TP53	Q13131	PRKAA1	S269	N263H	263	Missense	distal	-6	no	57.267	56.084	EPSD	COSMIC	56.683	Loss
CAMK_CAMKL_AMPK_PRKAA1_ST	P04637	TP53	Q13131	PRKAA1	S269	G266A	266	Missense	distal	-3	no	57.267	55.445	EPSD	COSMIC	56.683	Loss
CAMK_CAMKL_AMPK_PRKAA1_ST	P04637	TP53	Q13131	PRKAA1	S269	S269N	269	Missense	central	0	yes	57.267	0.000	EPSD	COSMIC	56.683	Loss
CAMK_CAMKL_AMPK_PRKAA1_ST	P04637	TP53	Q13131	PRKAA1	S269	V274I	274	Missense	distal	5	no	57.267	57.284	EPSD	COSMIC	56.683	Up-regulation
CAMK_CAMKL_AMPK_PRKAA1_ST	P04637	TP53	Q13131	PRKAA1	S269	L265M	265	Missense	distal	-4	no	57.267	57.294	EPSD	COSMIC	56.683	Up-regulation
CAMK_CAMKL_AMPK_PRKAA1_ST	P04637	TP53	Q13131	PRKAA1	S269	F270Y	270	Missense	proximal	1	no	57.267	55.043	EPSD	COSMIC	56.683	Loss
CAMK_CAMKL_AMPK_PRKAA1_ST	P04637	TP53	Q13131	PRKAA1	S269	L264V	264	Missense	distal	-5	no	57.267	52.403	EPSD	COSMIC	56.683	Loss
CAMK_CAMKL_AMPK_PRKAA1_ST	P04637	TP53	Q13131	PRKAA1	S269	S269G	269	Missense	central	0	yes	57.267	0.000	EPSD	COSMIC	56.683	Loss
CAMK_CAMKL_AMPK_PRKAA1_ST	P04637	TP53	Q13131	PRKAA1	S269	R273Q	273	Missense	distal	4	no	57.267	53.183	EPSD	COSMIC	56.683	Loss
CAMK_CAMKL_AMPK_PRKAA1_ST	P04637	TP53	Q13131	PRKAA1	S269	N268H	268	Missense	proximal	-1	no	57.267	57.293	EPSD	COSMIC	56.683	Up-regulation
CAMK_CAMKL_AMPK_PRKAA1_ST	P04637	TP53	Q13131	PRKAA1	S269	G262D	262	Missense	distal	-7	no	57.267	55.962	EPSD	COSMIC;GDSC;CCLE	56.683	Loss
CAMK_CAMKL_AMPK_PRKAA1_ST	P04637	TP53	Q13131	PRKAA1	S269	N263I	263	Missense	distal	-6	no	57.267	54.473	EPSD	COSMIC	56.683	Loss
CAMK_CAMKL_AMPK_PRKAA1_ST	P04637	TP53	Q13131	PRKAA1	S269	L264P	264	Missense	distal	-5	no	57.267	52.526	EPSD	COSMIC	56.683	Loss
CAMK_CAMKL_AMPK_PRKAA1_ST	P04637	TP53	Q13131	PRKAA1	S269	E271P	271	Missense	proximal	2	no	57.267	57.207	EPSD	COSMIC	56.683	Down-regulation
CAMK_CAMKL_AMPK_PRKAA1_ST	P04637	TP53	Q13131	PRKAA1	S269	L264R	264	Missense	distal	-5	no	57.267	56.090	EPSD	COSMIC;GDSC;CCLE	56.683	Loss
CAMK_CAMKL_AMPK_PRKAA1_ST	P04637	TP53	Q13131	PRKAA1	S269	R273Y	273	Missense	distal	4	no	57.267	53.938	EPSD	COSMIC;CCLE	56.683	Loss
CAMK_CAMKL_AMPK_PRKAA1_ST	P04637	TP53	Q13131	PRKAA1	S269	N263D	263	Missense	distal	-6	no	57.267	59.532	EPSD	COSMIC	56.683	Up-regulation
CAMK_CAMKL_AMPK_PRKAA1_ST	P04637	TP53	Q13131	PRKAA1	S269	A276T	276	Missense	distal	7	no	57.267	56.893	EPSD	COSMIC	56.683	Down-regulation
CAMK_CAMKL_AMPK_PRKAA1_ST	P04637	TP53	Q13131	PRKAA1	S269	S269C	269	Missense	central	0	yes	57.267	0.000	EPSD	COSMIC	56.683	Loss
CAMK_CAMKL_AMPK_PRKAA1_ST	P04637	TP53	Q13131	PRKAA1	S269	L264I	264	Missense	distal	-5	no	57.267	57.845	EPSD	COSMIC	56.683	Up-regulation
CAMK_CAMKL_AMPK_PRKAA1_ST	P04637	TP53	Q13131	PRKAA1	S269	N268K	268	Missense	proximal	-1	no	57.267	57.200	EPSD	COSMIC	56.683	Down-regulation
CAMK_CAMKL_AMPK_PRKAA1_ST	P04637	TP53	Q13131	PRKAA1	S269	A276F	276	Missense	distal	7	no	57.267	55.871	EPSD	COSMIC	56.683	Loss
CAMK_CAMKL_AMPK_PRKAA1_ST	P04637	TP53	Q13131	PRKAA1	S269	G266T	266	Missense	distal	-3	no	57.267	52.191	EPSD	COSMIC	56.683	Loss
CAMK_CAMKL_AMPK_PRKAA1_ST	P04637	TP53	Q13131	PRKAA1	S269	G266K	266	Missense	distal	-3	no	57.267	61.661	EPSD	COSMIC	56.683	Up-regulation
CAMK_CAMKL_AMPK_PRKAA1_ST	P04637	TP53	Q13131	PRKAA1	S269	E271G	271	Missense	proximal	2	no	57.267	56.154	EPSD	COSMIC	56.683	Loss
CAMK_CAMKL_AMPK_PRKAA1_ST	P04637	TP53	Q13131	PRKAA1	S269	L264Q	264	Missense	distal	-5	no	57.267	50.408	EPSD	COSMIC	56.683	Loss
CAMK_CAMKL_AMPK_PRKAA1_ST	P04637	TP53	Q13131	PRKAA1	S269	S269I	269	Missense	central	0	yes	57.267	0.000	EPSD	COSMIC	56.683	Loss
CAMK_CAMKL_AMPK_PRKAA1_ST	P04637	TP53	Q13131	PRKAA1	S269	S269R	269	Missense	central	0	yes	57.267	0.000	EPSD	COSMIC	56.683	Loss
CAMK_CAMKL_AMPK_PRKAA1_ST	P04637	TP53	Q13131	PRKAA1	S269	G262R	262	Missense	distal	-7	no	57.267	55.851	EPSD	COSMIC	56.683	Loss
CAMK_CAMKL_AMPK_PRKAA1_ST	P04637	TP53	Q13131	PRKAA1	S269	N263K	263	Missense	distal	-6	no	57.267	56.136	EPSD	COSMIC	56.683	Loss
CAMK_CAMKL_AMPK_PRKAA1_ST	P04637	TP53	Q13131	PRKAA1	S269	V272K	272	Missense	distal	3	no	57.267	57.126	EPSD	COSMIC	56.683	Down-regulation
CAMK_CAMKL_AMPK_PRKAA1_ST	P04637	TP53	Q13131	PRKAA1	S269	N268F	268	Missense	proximal	-1	no	57.267	57.260	EPSD	COSMIC	56.683	Down-regulation
CAMK_CAMKL_AMPK_PRKAA1_ST	P04637	TP53	Q13131	PRKAA1	S269	L265Q	265	Missense	distal	-4	no	57.267	58.357	EPSD	COSMIC	56.683	Up-regulation
CAMK_CAMKL_AMPK_PRKAA1_ST	P04637	TP53	Q13131	PRKAA1	S269	N268S	268	Missense	proximal	-1	no	57.267	57.306	EPSD	COSMIC	56.683	Up-regulation
CAMK_CAMKL_AMPK_PRKAA1_ST	P04637	TP53	Q13131	PRKAA1	S269	G262S	262	Missense	distal	-7	no	57.267	56.847	EPSD	COSMIC;GDSC	56.683	Down-regulation
CAMK_CAMKL_AMPK_PRKAA1_ST	P04637	TP53	Q13131	PRKAA1	S269	G266S	266	Missense	distal	-3	no	57.267	56.907	EPSD	COSMIC	56.683	Down-regulation
CAMK_CAMKL_AMPK_PRKAA1_ST	P04637	TP53	Q13131	PRKAA1	T312	P316L	316	Missense	distal	4	no	51.177	57.917	EPSD	COSMIC	56.683	Gain
CAMK_CAMKL_AMPK_PRKAA1_ST	P04637	TP53	Q13131	PRKAA1	T312	P309R	309	Missense	distal	-3	no	51.177	60.037	EPSD	COSMIC	56.683	Gain
CAMK_CAMKL_AMPK_PRKAA1_ST	P04637	TP53	Q13131	PRKAA1	S313	Q317R	317	Missense	distal	4	no	54.373	58.457	EPSD	COSMIC	56.683	Gain
CAMK_CAMKL_AMPK_PRKAA1_ST	P04637	TP53	Q13131	PRKAA1	S313	Q317K	317	Missense	distal	4	no	54.373	58.453	EPSD	COSMIC	56.683	Gain
CAMK_CAMKL_AMPK_PRKAA1_ST	P04637	TP53	Q13131	PRKAA1	S313	S314F	314	Missense	proximal	1	no	54.373	58.913	EPSD	COSMIC	56.683	Gain
CAMK_CAMKL_AMPK_PRKAA1_ST	P04637	TP53	Q13131	PRKAA1	S313	Q317P	317	Missense	distal	4	no	54.373	57.199	EPSD	COSMIC	56.683	Gain
CAMK_CAMKL_AMPK_PRKAA1_ST	P04637	TP53	Q13131	PRKAA1	S366	S367F	367	Missense	proximal	1	no	54.310	58.850	EPSD	COSMIC	56.683	Gain
CAMK_CAMKL_AMPK_PRKAA1_ST	P04637	TP53	Q13131	PRKAA1	S366	G361E	361	Missense	distal	-5	no	54.310	56.876	EPSD	COSMIC	56.683	Gain
CAMK_CAMKL_AMPK_PRKAA1_ST	P04637	TP53	Q13131	PRKAA1	S366	G361R	361	Missense	distal	-5	no	54.310	57.318	EPSD	COSMIC	56.683	Gain
CAMK_CAMKL_AMPK_PRKAA1_ST	P04637	TP53	Q13131	PRKAA1	S367	S367F	367	Missense	central	0	yes	60.689	0.000	EPSD	COSMIC	56.683	Loss
CAMK_CAMKL_AMPK_PRKAA1_ST	P04637	TP53	Q13131	PRKAA1	S367	K370N	370	Missense	distal	3	no	60.689	61.927	EPSD	COSMIC	56.683	Up-regulation
CAMK_CAMKL_AMPK_PRKAA1_ST	P04637	TP53	Q13131	PRKAA1	S367	G361E	361	Missense	distal	-6	no	60.689	59.802	EPSD	COSMIC	56.683	Down-regulation
CAMK_CAMKL_AMPK_PRKAA1_ST	P04637	TP53	Q13131	PRKAA1	S367	A364D	364	Missense	distal	-3	no	60.689	61.693	EPSD	COSMIC	56.683	Up-regulation
CAMK_CAMKL_AMPK_PRKAA1_ST	P04637	TP53	Q13131	PRKAA1	S367	H365Y	365	Missense	proximal	-2	no	60.689	63.087	EPSD	COSMIC	56.683	Up-regulation
CAMK_CAMKL_AMPK_PRKAA1_ST	P04637	TP53	Q13131	PRKAA1	S367	G360A	360	Missense	distal	-7	no	60.689	57.566	EPSD	COSMIC	56.683	Down-regulation
CAMK_CAMKL_AMPK_PRKAA1_ST	P04637	TP53	Q13131	PRKAA1	S367	A364T	364	Missense	distal	-3	no	60.689	57.435	EPSD	COSMIC	56.683	Down-regulation
CAMK_CAMKL_AMPK_PRKAA1_ST	P04637	TP53	Q13131	PRKAA1	S367	S366A	366	Missense	proximal	-1	no	60.689	60.711	EPSD	COSMIC	56.683	Up-regulation
CAMK_CAMKL_AMPK_PRKAA1_ST	P04637	TP53	Q13131	PRKAA1	S367	G361R	361	Missense	distal	-6	no	60.689	61.653	EPSD	COSMIC	56.683	Up-regulation
CAMK_CAMKL_AMPK_PRKAA1_ST	P04637	TP53	Q13131	PRKAA1	S367	K370Q	370	Missense	distal	3	no	60.689	60.676	EPSD	COSMIC	56.683	Down-regulation
CAMK_CAMKL_AMPK_PRKAA1_ST	P04637	TP53	Q13131	PRKAA1	S367	K373R	373	Missense	distal	6	no	60.689	60.637	EPSD	COSMIC	56.683	Down-regulation
CAMK_CAMKL_AMPK_PRKAA1_ST	P04637	TP53	Q13131	PRKAA1	S367	G374S	374	Missense	distal	7	no	60.689	60.739	EPSD	COSMIC	56.683	Up-regulation
CAMK_CAMKL_AMPK_PRKAA1_ST	P04637	TP53	Q13131	PRKAA1	S367	S371P	371	Missense	distal	4	no	60.689	60.537	EPSD	COSMIC	56.683	Down-regulation
CAMK_CAMKL_AMPK_PRKAA1_ST	P04637	TP53	Q13131	PRKAA1	S378	L383F	383	Missense	distal	5	no	56.911	56.750	EPSD	COSMIC	56.683	Down-regulation
CAMK_CAMKL_AMPK_PRKAA1_ST	P04637	TP53	Q13131	PRKAA1	S378	R379H	379	Missense	proximal	1	no	56.911	59.909	EPSD	COSMIC	56.683	Up-regulation
CAMK_CAMKL_AMPK_PRKAA1_ST	P04637	TP53	Q13131	PRKAA1	S378	S376T	376	Missense	proximal	-2	no	56.911	54.229	EPSD	COSMIC	56.683	Loss
CAMK_CAMKL_AMPK_PRKAA1_ST	P04637	TP53	Q13131	PRKAA1	S378	H380Y	380	Missense	proximal	2	no	56.911	56.055	EPSD	COSMIC	56.683	Loss
CAMK_CAMKL_AMPK_PRKAA1_ST	P04637	TP53	Q13131	PRKAA1	S378	T377I	377	Missense	proximal	-1	no	56.911	56.983	EPSD	COSMIC	56.683	Up-regulation
CAMK_CAMKL_AMPK_PRKAA1_ST	P04637	TP53	Q13131	PRKAA1	S378	S378F	378	Missense	central	0	yes	56.911	0.000	EPSD	COSMIC	56.683	Loss
CAMK_CAMKL_AMPK_PRKAA1_ST	P04637	TP53	Q13131	PRKAA1	S378	K381N	381	Missense	distal	3	no	56.911	58.149	EPSD	COSMIC	56.683	Up-regulation
CAMK_CAMKL_AMPK_PRKAA1_ST	P04637	TP53	Q13131	PRKAA1	S378	R379P	379	Missense	proximal	1	no	56.911	57.266	EPSD	COSMIC	56.683	Up-regulation
CAMK_CAMKL_AMPK_PRKAA1_ST	P04637	TP53	Q13131	PRKAA1	S378	M384I	384	Missense	distal	6	no	56.911	56.482	EPSD	COSMIC	56.683	Loss
CAMK_CAMKL_AMPK_PRKAA1_ST	P04637	TP53	Q13131	PRKAA1	S378	K373R	373	Missense	distal	-5	no	56.911	60.001	EPSD	COSMIC	56.683	Up-regulation
CAMK_CAMKL_AMPK_PRKAA1_ST	P04637	TP53	Q13131	PRKAA1	S378	S376F	376	Missense	proximal	-2	no	56.911	54.713	EPSD	COSMIC	56.683	Loss
CAMK_CAMKL_AMPK_PRKAA1_ST	P04637	TP53	Q13131	PRKAA1	S378	G374S	374	Missense	distal	-4	no	56.911	59.454	EPSD	COSMIC	56.683	Up-regulation
CAMK_CAMKL_AMPK_PRKAA1_ST	P04637	TP53	Q13131	PRKAA1	S378	S376A	376	Missense	proximal	-2	no	56.911	54.887	EPSD	COSMIC	56.683	Loss
CAMK_CAMKL_AMPK_PRKAA1_ST	P04637	TP53	Q13131	PRKAA1	S378	S371P	371	Missense	distal	-7	no	56.911	54.644	EPSD	COSMIC	56.683	Loss
CAMK_CAMKL_AMPK_PRKAA1_ST	P00533	EGFR	Q13131	PRKAA1	S457	I462M	462	Missense	distal	5	no	59.280	59.172	EPSD	COSMIC	56.683	Down-regulation
CAMK_CAMKL_AMPK_PRKAA1_ST	P00533	EGFR	Q13131	PRKAA1	S457	G459S	459	Missense	proximal	2	no	59.280	59.790	EPSD	COSMIC	56.683	Up-regulation
CAMK_CAMKL_AMPK_PRKAA1_ST	P00533	EGFR	Q13131	PRKAA1	S457	V461M	461	Missense	distal	4	no	59.280	61.201	EPSD	COSMIC	56.683	Up-regulation
CAMK_CAMKL_AMPK_PRKAA1_ST	P00533	EGFR	Q13131	PRKAA1	S457	R451H	451	Missense	distal	-6	no	59.280	57.747	EPSD	COSMIC	56.683	Down-regulation
CAMK_CAMKL_AMPK_PRKAA1_ST	P00533	EGFR	Q13131	PRKAA1	S457	G459D	459	Missense	proximal	2	no	59.280	60.432	EPSD	COSMIC	56.683	Up-regulation
CAMK_CAMKL_AMPK_PRKAA1_ST	P00533	EGFR	Q13131	PRKAA1	S457	R451C	451	Missense	distal	-6	no	59.280	55.203	EPSD	COSMIC	56.683	Loss
CAMK_CAMKL_AMPK_PRKAA1_ST	P00533	EGFR	Q13131	PRKAA1	S457	R451F	451	Missense	distal	-6	no	59.280	58.912	EPSD	COSMIC	56.683	Down-regulation
CAMK_CAMKL_AMPK_PRKAA1_ST	P00533	EGFR	Q13131	PRKAA1	S457	L453F	453	Missense	distal	-4	no	59.280	58.928	EPSD	COSMIC	56.683	Down-regulation
CAMK_CAMKL_AMPK_PRKAA1_ST	P00533	EGFR	Q13131	PRKAA1	S457	K454N	454	Missense	distal	-3	no	59.280	57.985	EPSD	COSMIC	56.683	Down-regulation
CAMK_CAMKL_AMPK_PRKAA1_ST	P00533	EGFR	Q13131	PRKAA1	S457	G459A	459	Missense	proximal	2	no	59.280	59.589	EPSD	COSMIC	56.683	Up-regulation
CAMK_CAMKL_AMPK_PRKAA1_ST	P00533	EGFR	Q13131	PRKAA1	S720	A722V	722	Missense	proximal	2	no	57.037	58.184	EPSD	COSMIC	56.683	Up-regulation
CAMK_CAMKL_AMPK_PRKAA1_ST	P00533	EGFR	Q13131	PRKAA1	S720	G721W	721	Missense	proximal	1	no	57.037	56.068	EPSD	COSMIC	56.683	Loss
CAMK_CAMKL_AMPK_PRKAA1_ST	P00533	EGFR	Q13131	PRKAA1	S720	G719S	719	Missense	proximal	-1	no	57.037	57.032	EPSD	COSMIC;GDSC;CCLE	56.683	Down-regulation
CAMK_CAMKL_AMPK_PRKAA1_ST	P00533	EGFR	Q13131	PRKAA1	S720	G719X	719	Missense	proximal	-1	no	57.037	57.177	EPSD	COSMIC	56.683	Up-regulation
CAMK_CAMKL_AMPK_PRKAA1_ST	P00533	EGFR	Q13131	PRKAA1	S720	K714N	714	Missense	distal	-6	no	57.037	58.169	EPSD	COSMIC	56.683	Up-regulation
CAMK_CAMKL_AMPK_PRKAA1_ST	P00533	EGFR	Q13131	PRKAA1	S720	V717E	717	Missense	distal	-3	no	57.037	56.970	EPSD	COSMIC	56.683	Down-regulation
CAMK_CAMKL_AMPK_PRKAA1_ST	P00533	EGFR	Q13131	PRKAA1	S720	S720F	720	Missense	central	0	yes	57.037	0.000	EPSD	COSMIC	56.683	Loss
CAMK_CAMKL_AMPK_PRKAA1_ST	P00533	EGFR	Q13131	PRKAA1	S720	L718P	718	Missense	proximal	-2	no	57.037	60.012	EPSD	COSMIC	56.683	Up-regulation
CAMK_CAMKL_AMPK_PRKAA1_ST	P00533	EGFR	Q13131	PRKAA1	S720	G724D	724	Missense	distal	4	no	57.037	57.396	EPSD	COSMIC	56.683	Up-regulation
CAMK_CAMKL_AMPK_PRKAA1_ST	P00533	EGFR	Q13131	PRKAA1	S720	K713F	713	Missense	distal	-7	no	57.037	53.837	EPSD	COSMIC	56.683	Loss
CAMK_CAMKL_AMPK_PRKAA1_ST	P00533	EGFR	Q13131	PRKAA1	S720	S720P	720	Missense	central	0	yes	57.037	0.000	EPSD	COSMIC	56.683	Loss
CAMK_CAMKL_AMPK_PRKAA1_ST	P00533	EGFR	Q13131	PRKAA1	S720	Y727H	727	Missense	distal	7	no	57.037	55.476	EPSD	COSMIC	56.683	Loss
CAMK_CAMKL_AMPK_PRKAA1_ST	P00533	EGFR	Q13131	PRKAA1	S720	V717A	717	Missense	distal	-3	no	57.037	54.595	EPSD	COSMIC	56.683	Loss
CAMK_CAMKL_AMPK_PRKAA1_ST	P00533	EGFR	Q13131	PRKAA1	S720	Y727C	727	Missense	distal	7	no	57.037	56.236	EPSD	COSMIC	56.683	Loss
CAMK_CAMKL_AMPK_PRKAA1_ST	P00533	EGFR	Q13131	PRKAA1	S720	G721S	721	Missense	proximal	1	no	57.037	56.450	EPSD	COSMIC	56.683	Loss
CAMK_CAMKL_AMPK_PRKAA1_ST	P00533	EGFR	Q13131	PRKAA1	S720	L718Q	718	Missense	proximal	-2	no	57.037	58.686	EPSD	COSMIC	56.683	Up-regulation
CAMK_CAMKL_AMPK_PRKAA1_ST	P00533	EGFR	Q13131	PRKAA1	S720	K716R	716	Missense	distal	-4	no	57.037	60.218	EPSD	COSMIC	56.683	Up-regulation
CAMK_CAMKL_AMPK_PRKAA1_ST	P00533	EGFR	Q13131	PRKAA1	S720	I715L	715	Missense	distal	-5	no	57.037	56.459	EPSD	COSMIC	56.683	Loss
CAMK_CAMKL_AMPK_PRKAA1_ST	P00533	EGFR	Q13131	PRKAA1	S720	I715S	715	Missense	distal	-5	no	57.037	52.277	EPSD	COSMIC	56.683	Loss
CAMK_CAMKL_AMPK_PRKAA1_ST	P00533	EGFR	Q13131	PRKAA1	S720	G721D	721	Missense	proximal	1	no	57.037	55.611	EPSD	COSMIC	56.683	Loss
CAMK_CAMKL_AMPK_PRKAA1_ST	P00533	EGFR	Q13131	PRKAA1	S720	T725M	725	Missense	distal	5	no	57.037	56.847	EPSD	COSMIC	56.683	Down-regulation
CAMK_CAMKL_AMPK_PRKAA1_ST	P00533	EGFR	Q13131	PRKAA1	S720	F723S	723	Missense	distal	3	no	57.037	58.246	EPSD	COSMIC	56.683	Up-regulation
CAMK_CAMKL_AMPK_PRKAA1_ST	P00533	EGFR	Q13131	PRKAA1	S720	L718M	718	Missense	proximal	-2	no	57.037	57.050	EPSD	COSMIC	56.683	Up-regulation
CAMK_CAMKL_AMPK_PRKAA1_ST	P00533	EGFR	Q13131	PRKAA1	S720	K714E	714	Missense	distal	-6	no	57.037	56.667	EPSD	COSMIC	56.683	Loss
CAMK_CAMKL_AMPK_PRKAA1_ST	P00533	EGFR	Q13131	PRKAA1	S720	G719V	719	Missense	proximal	-1	no	57.037	56.962	EPSD	COSMIC	56.683	Down-regulation
CAMK_CAMKL_AMPK_PRKAA1_ST	P00533	EGFR	Q13131	PRKAA1	S720	V726M	726	Missense	distal	6	no	57.037	57.256	EPSD	COSMIC	56.683	Up-regulation
CAMK_CAMKL_AMPK_PRKAA1_ST	P00533	EGFR	Q13131	PRKAA1	S720	T725A	725	Missense	distal	5	no	57.037	57.038	EPSD	COSMIC	56.683	Up-regulation
CAMK_CAMKL_AMPK_PRKAA1_ST	P00533	EGFR	Q13131	PRKAA1	S720	L718V	718	Missense	proximal	-2	no	57.037	59.472	EPSD	COSMIC	56.683	Up-regulation
CAMK_CAMKL_AMPK_PRKAA1_ST	P00533	EGFR	Q13131	PRKAA1	S720	K716E	716	Missense	distal	-4	no	57.037	60.163	EPSD	COSMIC	56.683	Up-regulation
CAMK_CAMKL_AMPK_PRKAA1_ST	P00533	EGFR	Q13131	PRKAA1	S720	K714T	714	Missense	distal	-6	no	57.037	58.514	EPSD	COSMIC	56.683	Up-regulation
CAMK_CAMKL_AMPK_PRKAA1_ST	P00533	EGFR	Q13131	PRKAA1	S720	F723L	723	Missense	distal	3	no	57.037	56.264	EPSD	COSMIC	56.683	Loss
CAMK_CAMKL_AMPK_PRKAA1_ST	P00533	EGFR	Q13131	PRKAA1	S720	G721A	721	Missense	proximal	1	no	57.037	54.855	EPSD	COSMIC	56.683	Loss
CAMK_CAMKL_AMPK_PRKAA1_ST	P00533	EGFR	Q13131	PRKAA1	S752	L747P	747	Missense	distal	-5	no	59.697	54.956	EPSD	COSMIC	56.683	Loss
CAMK_CAMKL_AMPK_PRKAA1_ST	P00533	EGFR	Q13131	PRKAA1	S752	L747F	747	Missense	distal	-5	no	59.697	54.173	EPSD	COSMIC	56.683	Loss
CAMK_CAMKL_AMPK_PRKAA1_ST	P00533	EGFR	Q13131	PRKAA1	S752	L747H	747	Missense	distal	-5	no	59.697	53.140	EPSD	COSMIC	56.683	Loss
CAMK_CAMKL_AMPK_PRKAA1_ST	P00533	EGFR	Q13131	PRKAA1	S752	L747S	747	Missense	distal	-5	no	59.697	55.515	EPSD	COSMIC	56.683	Loss
CAMK_CAMKL_AMPK_PRKAA1_ST	P00533	EGFR	Q13131	PRKAA1	S752	A750P	750	Missense	proximal	-2	no	59.697	62.270	EPSD	COSMIC	56.683	Up-regulation
CAMK_CAMKL_AMPK_PRKAA1_ST	P00533	EGFR	Q13131	PRKAA1	S752	R748K	748	Missense	distal	-4	no	59.697	56.517	EPSD	COSMIC	56.683	Loss
CAMK_CAMKL_AMPK_PRKAA1_ST	P00533	EGFR	Q13131	PRKAA1	S752	I759V	759	Missense	distal	7	no	59.697	58.499	EPSD	COSMIC	56.683	Down-regulation
CAMK_CAMKL_AMPK_PRKAA1_ST	P00533	EGFR	Q13131	PRKAA1	S752	K754Q	754	Missense	proximal	2	no	59.697	59.104	EPSD	COSMIC	56.683	Down-regulation
CAMK_CAMKL_AMPK_PRKAA1_ST	P00533	EGFR	Q13131	PRKAA1	S752	T751A	751	Missense	proximal	-1	no	59.697	59.776	EPSD	COSMIC	56.683	Up-regulation
CAMK_CAMKL_AMPK_PRKAA1_ST	P00533	EGFR	Q13131	PRKAA1	S752	E758G	758	Missense	distal	6	no	59.697	59.295	EPSD	COSMIC	56.683	Down-regulation
CAMK_CAMKL_AMPK_PRKAA1_ST	P00533	EGFR	Q13131	PRKAA1	S752	K757N	757	Missense	distal	5	no	59.697	59.684	EPSD	COSMIC	56.683	Down-regulation
CAMK_CAMKL_AMPK_PRKAA1_ST	P00533	EGFR	Q13131	PRKAA1	S752	S752Y	752	Missense	central	0	yes	59.697	0.000	EPSD	COSMIC	56.683	Loss
CAMK_CAMKL_AMPK_PRKAA1_ST	P00533	EGFR	Q13131	PRKAA1	S752	T751I	751	Missense	proximal	-1	no	59.697	59.768	EPSD	COSMIC;GDSC;CCLE	56.683	Up-regulation
CAMK_CAMKL_AMPK_PRKAA1_ST	P00533	EGFR	Q13131	PRKAA1	S752	E746V	746	Missense	distal	-6	no	59.697	59.895	EPSD	COSMIC	56.683	Up-regulation
CAMK_CAMKL_AMPK_PRKAA1_ST	P00533	EGFR	Q13131	PRKAA1	S752	A750T	750	Missense	proximal	-2	no	59.697	59.038	EPSD	COSMIC	56.683	Down-regulation
CAMK_CAMKL_AMPK_PRKAA1_ST	P00533	EGFR	Q13131	PRKAA1	S752	S752F	752	Missense	central	0	yes	59.697	0.000	EPSD	COSMIC	56.683	Loss
CAMK_CAMKL_AMPK_PRKAA1_ST	P00533	EGFR	Q13131	PRKAA1	S752	E746A	746	Missense	distal	-6	no	59.697	61.746	EPSD	COSMIC;GDSC	56.683	Up-regulation
CAMK_CAMKL_AMPK_PRKAA1_ST	P00533	EGFR	Q13131	PRKAA1	S752	A755D	755	Missense	distal	3	no	59.697	64.417	EPSD	COSMIC;CCLE	56.683	Up-regulation
CAMK_CAMKL_AMPK_PRKAA1_ST	P00533	EGFR	Q13131	PRKAA1	S752	K754R	754	Missense	proximal	2	no	59.697	59.581	EPSD	COSMIC	56.683	Down-regulation
CAMK_CAMKL_AMPK_PRKAA1_ST	P00533	EGFR	Q13131	PRKAA1	S752	E749K	749	Missense	distal	-3	no	59.697	63.538	EPSD	COSMIC	56.683	Up-regulation
CAMK_CAMKL_AMPK_PRKAA1_ST	P00533	EGFR	Q13131	PRKAA1	S752	T751L	751	Missense	proximal	-1	no	59.697	59.780	EPSD	COSMIC	56.683	Up-regulation
CAMK_CAMKL_AMPK_PRKAA1_ST	P00533	EGFR	Q13131	PRKAA1	S752	E758K	758	Missense	distal	6	no	59.697	59.469	EPSD	COSMIC	56.683	Down-regulation
CAMK_CAMKL_AMPK_PRKAA1_ST	P00533	EGFR	Q13131	PRKAA1	S752	K745R	745	Missense	distal	-7	no	59.697	58.094	EPSD	COSMIC	56.683	Down-regulation
CAMK_CAMKL_AMPK_PRKAA1_ST	P00533	EGFR	Q13131	PRKAA1	S752	E746I	746	Missense	distal	-6	no	59.697	58.404	EPSD	COSMIC	56.683	Down-regulation
CAMK_CAMKL_AMPK_PRKAA1_ST	P00533	EGFR	Q13131	PRKAA1	S752	A755T	755	Missense	distal	3	no	59.697	62.612	EPSD	COSMIC	56.683	Up-regulation
CAMK_CAMKL_AMPK_PRKAA1_ST	P00533	EGFR	Q13131	PRKAA1	S752	K754A	754	Missense	proximal	2	no	59.697	59.287	EPSD	COSMIC	56.683	Down-regulation
CAMK_CAMKL_AMPK_PRKAA1_ST	P00533	EGFR	Q13131	PRKAA1	S752	N756S	756	Missense	distal	4	no	59.697	61.167	EPSD	COSMIC	56.683	Up-regulation
CAMK_CAMKL_AMPK_PRKAA1_ST	P00533	EGFR	Q13131	PRKAA1	S752	N756Y	756	Missense	distal	4	no	59.697	58.944	EPSD	COSMIC	56.683	Down-regulation
CAMK_CAMKL_AMPK_PRKAA1_ST	P00533	EGFR	Q13131	PRKAA1	S752	K757R	757	Missense	distal	5	no	59.697	59.756	EPSD	COSMIC	56.683	Up-regulation
CAMK_CAMKL_AMPK_PRKAA1_ST	P00533	EGFR	Q13131	PRKAA1	S752	A755G	755	Missense	distal	3	no	59.697	64.879	EPSD	COSMIC	56.683	Up-regulation
CAMK_CAMKL_AMPK_PRKAA1_ST	P00533	EGFR	Q13131	PRKAA1	S752	E746G	746	Missense	distal	-6	no	59.697	60.584	EPSD	COSMIC	56.683	Up-regulation
CAMK_CAMKL_AMPK_PRKAA1_ST	P00533	EGFR	Q13131	PRKAA1	S752	E749V	749	Missense	distal	-3	no	59.697	59.764	EPSD	COSMIC	56.683	Up-regulation
CAMK_CAMKL_AMPK_PRKAA1_ST	P00533	EGFR	Q13131	PRKAA1	S752	E749G	749	Missense	distal	-3	no	59.697	59.144	EPSD	COSMIC	56.683	Down-regulation
CAMK_CAMKL_AMPK_PRKAA1_ST	P00533	EGFR	Q13131	PRKAA1	S752	S752P	752	Missense	central	0	yes	59.697	0.000	EPSD	COSMIC	56.683	Loss
CAMK_CAMKL_AMPK_PRKAA1_ST	P00533	EGFR	Q13131	PRKAA1	S752	E758D	758	Missense	distal	6	no	59.697	59.224	EPSD	COSMIC	56.683	Down-regulation
CAMK_CAMKL_AMPK_PRKAA1_ST	P00533	EGFR	Q13131	PRKAA1	S752	K745T	745	Missense	distal	-7	no	59.697	57.236	EPSD	COSMIC	56.683	Down-regulation
CAMK_CAMKL_AMPK_PRKAA1_ST	P00533	EGFR	Q13131	PRKAA1	S752	E746K	746	Missense	distal	-6	no	59.697	60.067	EPSD	COSMIC;GDSC	56.683	Up-regulation
CAMK_CAMKL_AMPK_PRKAA1_ST	P00533	EGFR	Q13131	PRKAA1	S752	A755V	755	Missense	distal	3	no	59.697	64.573	EPSD	COSMIC	56.683	Up-regulation
CAMK_CAMKL_AMPK_PRKAA1_ST	P00533	EGFR	Q13131	PRKAA1	S752	L747V	747	Missense	distal	-5	no	59.697	54.833	EPSD	COSMIC	56.683	Loss
CAMK_CAMKL_AMPK_PRKAA1_ST	P00533	EGFR	Q13131	PRKAA1	S752	T751P	751	Missense	proximal	-1	no	59.697	59.709	EPSD	COSMIC	56.683	Up-regulation
CAMK_CAMKL_AMPK_PRKAA1_ST	P00533	EGFR	Q13131	PRKAA1	S752	R748I	748	Missense	distal	-4	no	59.697	55.834	EPSD	COSMIC	56.683	Loss
CAMK_CAMKL_AMPK_PRKAA1_ST	P00533	EGFR	Q13131	PRKAA1	S752	K757M	757	Missense	distal	5	no	59.697	59.577	EPSD	COSMIC	56.683	Down-regulation
CAMK_CAMKL_AMPK_PRKAA1_ST	P00533	EGFR	Q13131	PRKAA1	S752	P753F	753	Missense	proximal	1	no	59.697	64.869	EPSD	COSMIC	56.683	Up-regulation
CAMK_CAMKL_AMPK_PRKAA1_ST	P00533	EGFR	Q13131	PRKAA1	S768	P772L	772	Missense	distal	4	no	49.950	56.690	EPSD	COSMIC	56.683	Gain
CAMK_CAMKL_AMPK_PRKAA1_ST	P00533	EGFR	Q13131	PRKAA1	T892	Y891D	891	Missense	proximal	-1	no	58.549	58.435	PhosphoSitePlus	COSMIC	56.683	Down-regulation
CAMK_CAMKL_AMPK_PRKAA1_ST	P00533	EGFR	Q13131	PRKAA1	T892	L887I	887	Missense	distal	-5	no	58.549	59.127	PhosphoSitePlus	COSMIC	56.683	Up-regulation
CAMK_CAMKL_AMPK_PRKAA1_ST	P00533	EGFR	Q13131	PRKAA1	T892	H893R	893	Missense	proximal	1	no	58.549	55.551	PhosphoSitePlus	COSMIC	56.683	Loss
CAMK_CAMKL_AMPK_PRKAA1_ST	P00533	EGFR	Q13131	PRKAA1	T892	V897I	897	Missense	distal	5	no	58.549	58.566	PhosphoSitePlus	COSMIC	56.683	Up-regulation
CAMK_CAMKL_AMPK_PRKAA1_ST	P00533	EGFR	Q13131	PRKAA1	T892	V897A	897	Missense	distal	5	no	58.549	58.649	PhosphoSitePlus	COSMIC	56.683	Up-regulation
CAMK_CAMKL_AMPK_PRKAA1_ST	P00533	EGFR	Q13131	PRKAA1	T892	R889G	889	Missense	distal	-3	no	58.549	49.514	PhosphoSitePlus	COSMIC	56.683	Loss
CAMK_CAMKL_AMPK_PRKAA1_ST	P00533	EGFR	Q13131	PRKAA1	S1039	S1036R	1036	Missense	distal	-3	no	49.728	59.123	EPSD	COSMIC	56.683	Gain
CAMK_CAMKL_AMPK_PRKAA1_ST	P00533	EGFR	Q13131	PRKAA1	T1041	A1048V	1048	Missense	distal	7	no	58.602	56.183	EPSD	COSMIC;GDSC;CCLE	56.683	Loss
CAMK_CAMKL_AMPK_PRKAA1_ST	P00533	EGFR	Q13131	PRKAA1	T1041	T1041A	1041	Missense	central	0	yes	58.602	0.000	EPSD	COSMIC	56.683	Loss
CAMK_CAMKL_AMPK_PRKAA1_ST	P00533	EGFR	Q13131	PRKAA1	T1041	S1036R	1036	Missense	distal	-5	no	58.602	61.607	EPSD	COSMIC	56.683	Up-regulation
CAMK_CAMKL_AMPK_PRKAA1_ST	P00533	EGFR	Q13131	PRKAA1	T1041	V1047M	1047	Missense	distal	6	no	58.602	58.820	EPSD	COSMIC	56.683	Up-regulation
CAMK_CAMKL_AMPK_PRKAA1_ST	P00533	EGFR	Q13131	PRKAA1	T1041	L1034I	1034	Missense	distal	-7	no	58.602	58.678	EPSD	COSMIC	56.683	Up-regulation
CAMK_CAMKL_AMPK_PRKAA1_ST	P00533	EGFR	Q13131	PRKAA1	T1041	S1045F	1045	Missense	distal	4	no	58.602	60.995	EPSD	COSMIC	56.683	Up-regulation
CAMK_CAMKL_AMPK_PRKAA1_ST	P00533	EGFR	Q13131	PRKAA1	T1041	A1048S	1048	Missense	distal	7	no	58.602	58.473	EPSD	COSMIC	56.683	Down-regulation
CAMK_CAMKL_AMPK_PRKAA1_ST	P00533	EGFR	Q13131	PRKAA1	T1041	A1048T	1048	Missense	distal	7	no	58.602	58.228	EPSD	COSMIC	56.683	Down-regulation
CAMK_CAMKL_AMPK_PRKAA1_ST	P00533	EGFR	Q13131	PRKAA1	T1041	T1046I	1046	Missense	distal	5	no	58.602	58.519	EPSD	COSMIC	56.683	Down-regulation
CAMK_CAMKL_AMPK_PRKAA1_ST	P00533	EGFR	Q13131	PRKAA1	T1046	A1048V	1048	Missense	proximal	2	no	58.346	59.492	EPSD	COSMIC;GDSC;CCLE	56.683	Up-regulation
CAMK_CAMKL_AMPK_PRKAA1_ST	P00533	EGFR	Q13131	PRKAA1	T1046	C1049R	1049	Missense	distal	3	no	58.346	59.527	EPSD	COSMIC	56.683	Up-regulation
CAMK_CAMKL_AMPK_PRKAA1_ST	P00533	EGFR	Q13131	PRKAA1	T1046	T1041A	1041	Missense	distal	-5	no	58.346	60.338	EPSD	COSMIC	56.683	Up-regulation
CAMK_CAMKL_AMPK_PRKAA1_ST	P00533	EGFR	Q13131	PRKAA1	T1046	V1047M	1047	Missense	proximal	1	no	58.346	60.524	EPSD	COSMIC	56.683	Up-regulation
CAMK_CAMKL_AMPK_PRKAA1_ST	P00533	EGFR	Q13131	PRKAA1	T1046	S1045F	1045	Missense	proximal	-1	no	58.346	58.299	EPSD	COSMIC	56.683	Down-regulation
CAMK_CAMKL_AMPK_PRKAA1_ST	P00533	EGFR	Q13131	PRKAA1	T1046	A1048S	1048	Missense	proximal	2	no	58.346	58.546	EPSD	COSMIC	56.683	Up-regulation
CAMK_CAMKL_AMPK_PRKAA1_ST	P00533	EGFR	Q13131	PRKAA1	T1046	R1052G	1052	Missense	distal	6	no	58.346	58.224	EPSD	COSMIC	56.683	Down-regulation
CAMK_CAMKL_AMPK_PRKAA1_ST	P00533	EGFR	Q13131	PRKAA1	T1046	A1048T	1048	Missense	proximal	2	no	58.346	58.792	EPSD	COSMIC	56.683	Up-regulation
CAMK_CAMKL_AMPK_PRKAA1_ST	P00533	EGFR	Q13131	PRKAA1	T1046	T1046I	1046	Missense	central	0	yes	58.346	0.000	EPSD	COSMIC	56.683	Loss
CAMK_CAMKL_AMPK_PRKAA1_ST	P00533	EGFR	Q13131	PRKAA1	T1150	A1155D	1155	Missense	distal	5	no	66.138	66.199	EPSD	COSMIC	56.683	Up-regulation
CAMK_CAMKL_AMPK_PRKAA1_ST	P00533	EGFR	Q13131	PRKAA1	T1150	V1147I	1147	Missense	distal	-3	no	66.138	61.155	EPSD	COSMIC	56.683	Down-regulation
CAMK_CAMKL_AMPK_PRKAA1_ST	P00533	EGFR	Q13131	PRKAA1	T1150	D1152H	1152	Missense	proximal	2	no	66.138	65.885	EPSD	COSMIC	56.683	Down-regulation
CAMK_CAMKL_AMPK_PRKAA1_ST	P00533	EGFR	Q13131	PRKAA1	S1204	R1199M	1199	Missense	distal	-5	no	62.597	63.606	EPSD	COSMIC	56.683	Up-regulation
CAMK_CAMKL_AMPK_PRKAA1_ST	P00533	EGFR	Q13131	PRKAA1	S1204	S1204R	1204	Missense	central	0	yes	62.597	0.000	EPSD	COSMIC	56.683	Loss
CAMK_CAMKL_AMPK_PRKAA1_ST	P00533	EGFR	Q13131	PRKAA1	S1204	A1201T	1201	Missense	distal	-3	no	62.597	59.343	EPSD	COSMIC	56.683	Down-regulation
CAMK_CAMKL_AMPK_PRKAA1_ST	P00533	EGFR	Q13131	PRKAA1	S1204	F1207C	1207	Missense	distal	3	no	62.597	61.974	EPSD	COSMIC	56.683	Down-regulation
CAMK_CAMKL_AMPK_PRKAA1_ST	P00533	EGFR	Q13131	PRKAA1	S1204	R1199T	1199	Missense	distal	-5	no	62.597	58.110	EPSD	COSMIC	56.683	Down-regulation
CAMK_CAMKL_AMPK_PRKAA1_ST	P00533	EGFR	Q13131	PRKAA1	S1204	V1200I	1200	Missense	distal	-4	no	62.597	61.191	EPSD	COSMIC	56.683	Down-regulation
CAMK_CAMKL_AMPK_PRKAA1_ST	Q92538	GBF1	Q13131	PRKAA1	S222	G219R	219	Missense	distal	-3	no	51.120	60.155	EPSD	COSMIC;CCLE	56.683	Gain
CAMK_CAMKL_AMPK_PRKAA1_ST	Q92538	GBF1	Q13131	PRKAA1	S302	F296S	296	Missense	distal	-6	no	62.732	62.629	EPSD	COSMIC	56.683	Down-regulation
CAMK_CAMKL_AMPK_PRKAA1_ST	Q92538	GBF1	Q13131	PRKAA1	S325	E332K	332	Missense	distal	7	no	56.706	56.009	EPSD	COSMIC	56.683	Loss
CAMK_CAMKL_AMPK_PRKAA1_ST	Q92538	GBF1	Q13131	PRKAA1	S349	P354T	354	Missense	distal	5	no	57.047	57.053	EPSD	COSMIC	56.683	Up-regulation
CAMK_CAMKL_AMPK_PRKAA1_ST	Q92538	GBF1	Q13131	PRKAA1	S670	V668I	668	Missense	proximal	-2	no	57.868	55.983	EPSD	COSMIC	56.683	Loss
CAMK_CAMKL_AMPK_PRKAA1_ST	Q92538	GBF1	Q13131	PRKAA1	S670	G671E	671	Missense	proximal	1	no	57.868	56.230	EPSD	COSMIC	56.683	Loss
CAMK_CAMKL_AMPK_PRKAA1_ST	Q92538	GBF1	Q13131	PRKAA1	S1298	S1298P	1298	Missense	central	0	yes	59.577	0.000	EPSD	COSMIC	56.683	Loss
CAMK_CAMKL_AMPK_PRKAA1_ST	Q92538	GBF1	Q13131	PRKAA1	S1304	S1298P	1298	Missense	distal	-6	no	57.444	57.794	EPSD	COSMIC	56.683	Up-regulation
CAMK_CAMKL_AMPK_PRKAA1_ST	Q92538	GBF1	Q13131	PRKAA1	S1367	P1368H	1368	Missense	proximal	1	no	54.676	57.320	EPSD	COSMIC	56.683	Gain
CAMK_CAMKL_AMPK_PRKAA1_ST	Q92538	GBF1	Q13131	PRKAA1	S1444	R1448C	1448	Missense	distal	4	no	59.605	38.751	EPSD	COSMIC	56.683	Loss
CAMK_CAMKL_AMPK_PRKAA1_ST	Q92538	GBF1	Q13131	PRKAA1	S1444	S1444N	1444	Missense	central	0	yes	59.605	0.000	EPSD	COSMIC	56.683	Loss
CAMK_CAMKL_AMPK_PRKAA1_ST	Q92538	GBF1	Q13131	PRKAA1	S1444	H1440R	1440	Missense	distal	-4	no	59.605	62.992	EPSD	COSMIC	56.683	Up-regulation
CAMK_CAMKL_AMPK_PRKAA1_ST	Q92538	GBF1	Q13131	PRKAA1	S1453	L1459F	1459	Missense	distal	6	no	57.301	57.433	EPSD	COSMIC;GDSC;CCLE	56.683	Up-regulation
CAMK_CAMKL_AMPK_PRKAA1_ST	Q92538	GBF1	Q13131	PRKAA1	S1453	R1448C	1448	Missense	distal	-5	no	57.301	55.947	EPSD	COSMIC	56.683	Loss
CAMK_CAMKL_AMPK_PRKAA1_ST	Q92538	GBF1	Q13131	PRKAA1	S1453	S1453F	1453	Missense	central	0	yes	57.301	0.000	EPSD	COSMIC	56.683	Loss
CAMK_CAMKL_AMPK_PRKAA1_ST	Q92538	GBF1	Q13131	PRKAA1	S1453	E1455D	1455	Missense	proximal	2	no	57.301	57.340	EPSD	COSMIC;GDSC;CCLE	56.683	Up-regulation
CAMK_CAMKL_AMPK_PRKAA1_ST	Q92538	GBF1	Q13131	PRKAA1	S1457	L1459F	1459	Missense	proximal	2	no	64.775	64.538	EPSD	COSMIC;GDSC;CCLE	56.683	Down-regulation
CAMK_CAMKL_AMPK_PRKAA1_ST	Q92538	GBF1	Q13131	PRKAA1	S1457	S1453F	1453	Missense	distal	-4	no	64.775	62.928	EPSD	COSMIC	56.683	Down-regulation
CAMK_CAMKL_AMPK_PRKAA1_ST	Q92538	GBF1	Q13131	PRKAA1	S1457	E1455D	1455	Missense	proximal	-2	no	64.775	64.199	EPSD	COSMIC;GDSC;CCLE	56.683	Down-regulation
CAMK_CAMKL_AMPK_PRKAA1_ST	Q92538	GBF1	Q13131	PRKAA1	S1465	L1459F	1459	Missense	distal	-6	no	59.588	59.381	EPSD	COSMIC;GDSC;CCLE	56.683	Down-regulation
CAMK_CAMKL_AMPK_PRKAA1_ST	Q92538	GBF1	Q13131	PRKAA1	S1773	S1779T	1779	Missense	distal	6	no	57.439	57.373	EPSD	COSMIC;GDSC	56.683	Down-regulation
CAMK_CAMKL_AMPK_PRKAA1_ST	Q92538	GBF1	Q13131	PRKAA1	S1780	S1779T	1779	Missense	proximal	-1	no	60.218	60.161	EPSD	COSMIC;GDSC	56.683	Down-regulation
CAMK_CAMKL_AMPK_PRKAA1_ST	Q92538	GBF1	Q13131	PRKAA1	S1781	S1779T	1779	Missense	proximal	-2	no	57.870	55.187	EPSD	COSMIC;GDSC	56.683	Loss
CAMK_CAMKL_AMPK_PRKAA1_ST	P60891	PRPS1	Q13131	PRKAA1	S180	S180P	180	Missense	central	0	yes	66.721	0.000	PhosphoSitePlus	COSMIC	56.683	Loss
CAMK_CAMKL_AMPK_PRKAA1_ST	P60891	PRPS1	Q13131	PRKAA1	S180	T179P	179	Missense	proximal	-1	no	66.721	66.733	PhosphoSitePlus	COSMIC	56.683	Up-regulation
CAMK_CAMKL_AMPK_PRKAA1_ST	P60891	PRPS1	Q13131	PRKAA1	S180	G174R	174	Missense	distal	-6	no	66.721	67.686	PhosphoSitePlus	COSMIC	56.683	Up-regulation
CAMK_CAMKL_AMPK_PRKAA1_ST	P60891	PRPS1	Q13131	PRKAA1	S180	K176E	176	Missense	distal	-4	no	66.721	69.846	PhosphoSitePlus	COSMIC	56.683	Up-regulation
CAMK_CAMKL_AMPK_PRKAA1_ST	P60891	PRPS1	Q13131	PRKAA1	S180	L185I	185	Missense	distal	5	no	66.721	66.652	PhosphoSitePlus	COSMIC	56.683	Down-regulation
CAMK_CAMKL_AMPK_PRKAA1_ST	P60891	PRPS1	Q13131	PRKAA1	S308	G306V	306	Missense	proximal	-2	no	55.922	59.235	EPSD	COSMIC	56.683	Gain
CAMK_CAMKL_AMPK_PRKAA1_ST	P19429	TNNI3	Q13131	PRKAA1	S23	R27H	27	Missense	distal	4	no	64.699	61.698	PhosphoSitePlus;EPSD	COSMIC	56.683	Down-regulation
CAMK_CAMKL_AMPK_PRKAA1_ST	P19429	TNNI3	Q13131	PRKAA1	S23	S23P	23	Missense	central	0	yes	64.699	0.000	PhosphoSitePlus;EPSD	COSMIC	56.683	Loss
CAMK_CAMKL_AMPK_PRKAA1_ST	P19429	TNNI3	Q13131	PRKAA1	S24	R27H	27	Missense	distal	3	no	67.603	64.034	EPSD;PhosphoSitePlus	COSMIC	56.683	Down-regulation
CAMK_CAMKL_AMPK_PRKAA1_ST	P19429	TNNI3	Q13131	PRKAA1	S24	S23P	23	Missense	proximal	-1	no	67.603	67.558	EPSD;PhosphoSitePlus	COSMIC	56.683	Down-regulation
CAMK_CAMKL_AMPK_PRKAA1_ST	P19429	TNNI3	Q13131	PRKAA1	T119	D113N	113	Missense	distal	-6	no	58.629	56.365	EPSD	COSMIC	56.683	Loss
CAMK_CAMKL_AMPK_PRKAA1_ST	P19429	TNNI3	Q13131	PRKAA1	T119	A126V	126	Missense	distal	7	no	58.629	56.211	EPSD	COSMIC	56.683	Loss
CAMK_CAMKL_AMPK_PRKAA1_ST	P19429	TNNI3	Q13131	PRKAA1	S150	Q156H	156	Missense	distal	6	no	59.336	59.012	EPSD;PhosphoSitePlus	COSMIC	56.683	Down-regulation
CAMK_CAMKL_AMPK_PRKAA1_ST	P19429	TNNI3	Q13131	PRKAA1	S150	A157V	157	Missense	distal	7	no	59.336	56.918	EPSD;PhosphoSitePlus	COSMIC	56.683	Down-regulation
CAMK_CAMKL_AMPK_PRKAA1_ST	P19429	TNNI3	Q13131	PRKAA1	S150	R146I	146	Missense	distal	-4	no	59.336	55.473	EPSD;PhosphoSitePlus	COSMIC	56.683	Loss
CAMK_CAMKL_AMPK_PRKAA1_ST	Q14457	BECN1	Q13131	PRKAA1	S234	Q240H	240	Missense	distal	6	no	57.551	57.227	EPSD	COSMIC	56.683	Down-regulation
CAMK_CAMKL_AMPK_PRKAA1_ST	Q8N122	RPTOR	Q13131	PRKAA1	S721	R718C	718	Missense	distal	-3	no	59.616	45.469	EPSD	COSMIC;CCLE	56.683	Loss
CAMK_CAMKL_AMPK_PRKAA1_ST	Q8N122	RPTOR	Q13131	PRKAA1	S721	P715S	715	Missense	distal	-6	no	59.616	59.266	EPSD	COSMIC	56.683	Down-regulation
CAMK_CAMKL_AMPK_PRKAA1_ST	Q8N122	RPTOR	Q13131	PRKAA1	S721	S719Y	719	Missense	proximal	-2	no	59.616	58.054	EPSD	COSMIC	56.683	Down-regulation
CAMK_CAMKL_AMPK_PRKAA1_ST	Q8N122	RPTOR	Q13131	PRKAA1	S721	S721N	721	Missense	central	0	yes	59.616	0.000	EPSD	COSMIC	56.683	Loss
CAMK_CAMKL_AMPK_PRKAA1_ST	Q8N122	RPTOR	Q13131	PRKAA1	S721	V720L	720	Missense	proximal	-1	no	59.616	59.711	EPSD	COSMIC	56.683	Up-regulation
CAMK_CAMKL_AMPK_PRKAA1_ST	Q8N122	RPTOR	Q13131	PRKAA1	S722	R718C	718	Missense	distal	-4	no	64.569	68.880	EPSD;PhosphoSitePlus	COSMIC;CCLE	56.683	Up-regulation
CAMK_CAMKL_AMPK_PRKAA1_ST	Q8N122	RPTOR	Q13131	PRKAA1	S722	P715S	715	Missense	distal	-7	no	64.569	66.836	EPSD;PhosphoSitePlus	COSMIC	56.683	Up-regulation
CAMK_CAMKL_AMPK_PRKAA1_ST	Q8N122	RPTOR	Q13131	PRKAA1	S722	S719Y	719	Missense	distal	-3	no	64.569	57.733	EPSD;PhosphoSitePlus	COSMIC	56.683	Down-regulation
CAMK_CAMKL_AMPK_PRKAA1_ST	Q8N122	RPTOR	Q13131	PRKAA1	S722	S721N	721	Missense	proximal	-1	no	64.569	64.529	EPSD;PhosphoSitePlus	COSMIC	56.683	Down-regulation
CAMK_CAMKL_AMPK_PRKAA1_ST	Q8N122	RPTOR	Q13131	PRKAA1	S722	V720L	720	Missense	proximal	-2	no	64.569	62.135	EPSD;PhosphoSitePlus	COSMIC	56.683	Down-regulation
CAMK_CAMKL_AMPK_PRKAA1_ST	Q8N122	RPTOR	Q13131	PRKAA1	T731	S738Y	738	Missense	distal	7	no	59.290	59.538	EPSD	COSMIC	56.683	Up-regulation
CAMK_CAMKL_AMPK_PRKAA1_ST	Q8N122	RPTOR	Q13131	PRKAA1	T731	A730T	730	Missense	proximal	-1	no	59.290	59.210	EPSD	COSMIC	56.683	Down-regulation
CAMK_CAMKL_AMPK_PRKAA1_ST	Q8N122	RPTOR	Q13131	PRKAA1	T731	T731A	731	Missense	central	0	yes	59.290	0.000	EPSD	COSMIC	56.683	Loss
CAMK_CAMKL_AMPK_PRKAA1_ST	Q8N122	RPTOR	Q13131	PRKAA1	S791	R789H	789	Missense	proximal	-2	no	62.734	60.013	EPSD	COSMIC;GDSC;CCLE	56.683	Down-regulation
CAMK_CAMKL_AMPK_PRKAA1_ST	Q8N122	RPTOR	Q13131	PRKAA1	S791	R788C	788	Missense	distal	-3	no	62.734	48.587	EPSD	COSMIC;GDSC;CCLE	56.683	Loss
CAMK_CAMKL_AMPK_PRKAA1_ST	Q8N122	RPTOR	Q13131	PRKAA1	S791	L796I	796	Missense	distal	5	no	62.734	62.665	EPSD	COSMIC	56.683	Down-regulation
CAMK_CAMKL_AMPK_PRKAA1_ST	Q8N122	RPTOR	Q13131	PRKAA1	S791	R788H	788	Missense	distal	-3	no	62.734	54.877	EPSD	COSMIC	56.683	Loss
CAMK_CAMKL_AMPK_PRKAA1_ST	Q8N122	RPTOR	Q13131	PRKAA1	S791	S798F	798	Missense	distal	7	no	62.734	61.466	EPSD	COSMIC	56.683	Down-regulation
CAMK_CAMKL_AMPK_PRKAA1_ST	Q8N122	RPTOR	Q13131	PRKAA1	S791	I784V	784	Missense	distal	-7	no	62.734	63.707	EPSD	COSMIC	56.683	Up-regulation
CAMK_CAMKL_AMPK_PRKAA1_ST	Q8N122	RPTOR	Q13131	PRKAA1	S791	S792F	792	Missense	proximal	1	no	62.734	67.274	EPSD	COSMIC	56.683	Up-regulation
CAMK_CAMKL_AMPK_PRKAA1_ST	Q8N122	RPTOR	Q13131	PRKAA1	S791	A790S	790	Missense	proximal	-1	no	62.734	62.712	EPSD	COSMIC	56.683	Down-regulation
CAMK_CAMKL_AMPK_PRKAA1_ST	Q8N122	RPTOR	Q13131	PRKAA1	S792	R789H	789	Missense	distal	-3	no	68.942	61.085	PhosphoSitePlus;EPSD	COSMIC;GDSC;CCLE	56.683	Down-regulation
CAMK_CAMKL_AMPK_PRKAA1_ST	Q8N122	RPTOR	Q13131	PRKAA1	S792	R788C	788	Missense	distal	-4	no	68.942	73.253	PhosphoSitePlus;EPSD	COSMIC;GDSC;CCLE	56.683	Up-regulation
CAMK_CAMKL_AMPK_PRKAA1_ST	Q8N122	RPTOR	Q13131	PRKAA1	S792	L796I	796	Missense	distal	4	no	68.942	65.865	PhosphoSitePlus;EPSD	COSMIC	56.683	Down-regulation
CAMK_CAMKL_AMPK_PRKAA1_ST	Q8N122	RPTOR	Q13131	PRKAA1	S792	R788H	788	Missense	distal	-4	no	68.942	65.555	PhosphoSitePlus;EPSD	COSMIC	56.683	Down-regulation
CAMK_CAMKL_AMPK_PRKAA1_ST	Q8N122	RPTOR	Q13131	PRKAA1	S792	S798F	798	Missense	distal	6	no	68.942	69.207	PhosphoSitePlus;EPSD	COSMIC	56.683	Up-regulation
CAMK_CAMKL_AMPK_PRKAA1_ST	Q8N122	RPTOR	Q13131	PRKAA1	S792	S792F	792	Missense	central	0	yes	68.942	0.000	PhosphoSitePlus;EPSD	COSMIC	56.683	Loss
CAMK_CAMKL_AMPK_PRKAA1_ST	Q8N122	RPTOR	Q13131	PRKAA1	S792	A790S	790	Missense	proximal	-2	no	68.942	70.966	PhosphoSitePlus;EPSD	COSMIC	56.683	Up-regulation
CAMK_CAMKL_AMPK_PRKAA1_ST	Q8N122	RPTOR	Q13131	PRKAA1	S792	L799H	799	Missense	distal	7	no	68.942	67.587	PhosphoSitePlus;EPSD	COSMIC	56.683	Down-regulation
CAMK_CAMKL_AMPK_PRKAA1_ST	Q8N122	RPTOR	Q13131	PRKAA1	S794	R789H	789	Missense	distal	-5	no	60.973	55.593	EPSD	COSMIC;GDSC;CCLE	56.683	Loss
CAMK_CAMKL_AMPK_PRKAA1_ST	Q8N122	RPTOR	Q13131	PRKAA1	S794	R788C	788	Missense	distal	-6	no	60.973	56.896	EPSD	COSMIC;GDSC;CCLE	56.683	Down-regulation
CAMK_CAMKL_AMPK_PRKAA1_ST	Q8N122	RPTOR	Q13131	PRKAA1	S794	L796I	796	Missense	proximal	2	no	60.973	60.417	EPSD	COSMIC	56.683	Down-regulation
CAMK_CAMKL_AMPK_PRKAA1_ST	Q8N122	RPTOR	Q13131	PRKAA1	S794	R788H	788	Missense	distal	-6	no	60.973	59.440	EPSD	COSMIC	56.683	Down-regulation
CAMK_CAMKL_AMPK_PRKAA1_ST	Q8N122	RPTOR	Q13131	PRKAA1	S794	S798F	798	Missense	distal	4	no	60.973	63.366	EPSD	COSMIC	56.683	Up-regulation
CAMK_CAMKL_AMPK_PRKAA1_ST	Q8N122	RPTOR	Q13131	PRKAA1	S794	S792F	792	Missense	proximal	-2	no	60.973	58.775	EPSD	COSMIC	56.683	Down-regulation
CAMK_CAMKL_AMPK_PRKAA1_ST	Q8N122	RPTOR	Q13131	PRKAA1	S794	A790S	790	Missense	distal	-4	no	60.973	61.373	EPSD	COSMIC	56.683	Up-regulation
CAMK_CAMKL_AMPK_PRKAA1_ST	Q8N122	RPTOR	Q13131	PRKAA1	S794	L799H	799	Missense	distal	5	no	60.973	60.784	EPSD	COSMIC	56.683	Down-regulation
CAMK_CAMKL_AMPK_PRKAA1_ST	Q8N122	RPTOR	Q13131	PRKAA1	S798	L799H	799	Missense	proximal	1	no	55.038	57.974	EPSD	COSMIC	56.683	Gain
CAMK_CAMKL_AMPK_PRKAA1_ST	Q8N122	RPTOR	Q13131	PRKAA1	S855	V850I	850	Missense	distal	-5	no	52.911	58.353	EPSD	COSMIC	56.683	Gain
CAMK_CAMKL_AMPK_PRKAA1_ST	Q8N122	RPTOR	Q13131	PRKAA1	T908	R905L	905	Missense	distal	-3	no	58.861	48.894	EPSD	COSMIC	56.683	Loss
CAMK_CAMKL_AMPK_PRKAA1_ST	Q8N122	RPTOR	Q13131	PRKAA1	T908	P911L	911	Missense	distal	3	no	58.861	59.117	EPSD	COSMIC	56.683	Up-regulation
CAMK_CAMKL_AMPK_PRKAA1_ST	Q8N122	RPTOR	Q13131	PRKAA1	T908	P906Q	906	Missense	proximal	-2	no	58.861	57.535	EPSD	COSMIC	56.683	Down-regulation
CAMK_CAMKL_AMPK_PRKAA1_ST	Q8N122	RPTOR	Q13131	PRKAA1	T908	R905W	905	Missense	distal	-3	no	58.861	-34.139	EPSD	COSMIC	56.683	Loss
CAMK_CAMKL_AMPK_PRKAA1_ST	Q8N122	RPTOR	Q13131	PRKAA1	T908	G910D	910	Missense	proximal	2	no	58.861	60.013	EPSD	COSMIC	56.683	Up-regulation
CAMK_CAMKL_AMPK_PRKAA1_ST	Q13621	SLC12A1	Q13131	PRKAA1	S885	M886V	886	Missense	proximal	1	no	56.974	54.795	EPSD	COSMIC	56.683	Loss
CAMK_CAMKL_AMPK_PRKAA1_ST	Q13621	SLC12A1	Q13131	PRKAA1	S1003	D1006Y	1006	Missense	distal	3	no	56.970	57.149	EPSD	COSMIC	56.683	Up-regulation
CAMK_CAMKL_AMPK_PRKAA1_ST	Q13621	SLC12A1	Q13131	PRKAA1	S1056	N1051I	1051	Missense	distal	-5	no	42.805	62.494	EPSD	COSMIC	56.683	Gain
CAMK_CAMKL_AMPK_PRKAA1_ST	O75925	PIAS1	Q13131	PRKAA1	T71	M70I	70	Missense	proximal	-1	no	59.434	59.431	EPSD	COSMIC	56.683	Down-regulation
CAMK_CAMKL_AMPK_PRKAA1_ST	O75925	PIAS1	Q13131	PRKAA1	S82	V80I	80	Missense	proximal	-2	no	69.186	67.301	EPSD	COSMIC	56.683	Down-regulation
CAMK_CAMKL_AMPK_PRKAA1_ST	O75925	PIAS1	Q13131	PRKAA1	S82	S83N	83	Missense	proximal	1	no	69.186	68.332	EPSD	COSMIC	56.683	Down-regulation
CAMK_CAMKL_AMPK_PRKAA1_ST	O75925	PIAS1	Q13131	PRKAA1	S82	P86T	86	Missense	distal	4	no	69.186	68.827	EPSD	COSMIC	56.683	Down-regulation
CAMK_CAMKL_AMPK_PRKAA1_ST	O75925	PIAS1	Q13131	PRKAA1	S155	T154I	154	Missense	proximal	-1	no	58.073	58.144	EPSD	COSMIC	56.683	Up-regulation
CAMK_CAMKL_AMPK_PRKAA1_ST	O75925	PIAS1	Q13131	PRKAA1	S254	I252V	252	Missense	proximal	-2	no	58.649	60.534	EPSD	COSMIC	56.683	Up-regulation
CAMK_CAMKL_AMPK_PRKAA1_ST	O75925	PIAS1	Q13131	PRKAA1	S476	P482S	482	Missense	distal	6	no	58.365	58.380	EPSD	COSMIC	56.683	Up-regulation
CAMK_CAMKL_AMPK_PRKAA1_ST	O75925	PIAS1	Q13131	PRKAA1	S485	P482S	482	Missense	distal	-3	no	62.320	61.785	EPSD	COSMIC	56.683	Down-regulation
CAMK_CAMKL_AMPK_PRKAA1_ST	Q13362	PPP2R5C	Q13131	PRKAA1	S497	D502E	502	Missense	distal	5	no	63.865	63.712	EPSD	COSMIC	56.683	Down-regulation
CAMK_CAMKL_AMPK_PRKAA1_ST	Q13362	PPP2R5C	Q13131	PRKAA1	S497	A493T	493	Missense	distal	-4	no	63.865	63.009	EPSD	COSMIC	56.683	Down-regulation
CAMK_CAMKL_AMPK_PRKAA1_ST	Q13362	PPP2R5C	Q13131	PRKAA1	S497	R490C	490	Missense	distal	-7	no	63.865	62.472	EPSD	COSMIC	56.683	Down-regulation
CAMK_CAMKL_AMPK_PRKAA1_ST	Q13362	PPP2R5C	Q13131	PRKAA1	S497	E498K	498	Missense	proximal	1	no	63.865	64.794	EPSD	COSMIC	56.683	Up-regulation
CAMK_CAMKL_AMPK_PRKAA1_ST	Q13362	PPP2R5C	Q13131	PRKAA1	S497	R490H	490	Missense	distal	-7	no	63.865	60.841	EPSD	COSMIC	56.683	Down-regulation
CAMK_CAMKL_AMPK_PRKAA1_ST	Q13362	PPP2R5C	Q13131	PRKAA1	S497	R495H	495	Missense	proximal	-2	no	63.865	61.144	EPSD	COSMIC	56.683	Down-regulation
CAMK_CAMKL_AMPK_PRKAA1_ST	Q13362	PPP2R5C	Q13131	PRKAA1	S520	E517K	517	Missense	distal	-3	no	53.053	56.893	EPSD	COSMIC	56.683	Gain
CAMK_CAMKL_AMPK_PRKAA1_ST	P41235	HNF4A	Q13131	PRKAA1	S143	R140Q	140	Missense	distal	-3	no	62.819	54.875	EPSD	COSMIC;GDSC;CCLE	56.683	Loss
CAMK_CAMKL_AMPK_PRKAA1_ST	P41235	HNF4A	Q13131	PRKAA1	S143	S148F	148	Missense	distal	5	no	62.819	62.690	EPSD	COSMIC	56.683	Down-regulation
CAMK_CAMKL_AMPK_PRKAA1_ST	P41235	HNF4A	Q13131	PRKAA1	S143	R141G	141	Missense	proximal	-2	no	62.819	60.754	EPSD	COSMIC	56.683	Down-regulation
CAMK_CAMKL_AMPK_PRKAA1_ST	P41235	HNF4A	Q13131	PRKAA1	S143	R141Q	141	Missense	proximal	-2	no	62.819	63.282	EPSD	COSMIC	56.683	Up-regulation
CAMK_CAMKL_AMPK_PRKAA1_ST	P41235	HNF4A	Q13131	PRKAA1	T166	Q164H	164	Missense	proximal	-2	no	65.932	62.749	EPSD	COSMIC	56.683	Down-regulation
CAMK_CAMKL_AMPK_PRKAA1_ST	P41235	HNF4A	Q13131	PRKAA1	T166	G171R	171	Missense	distal	5	no	65.932	66.011	EPSD	COSMIC	56.683	Up-regulation
CAMK_CAMKL_AMPK_PRKAA1_ST	P41235	HNF4A	Q13131	PRKAA1	T166	P168T	168	Missense	proximal	2	no	65.932	65.635	EPSD	COSMIC	56.683	Down-regulation
CAMK_CAMKL_AMPK_PRKAA1_ST	P41235	HNF4A	Q13131	PRKAA1	T166	S170F	170	Missense	distal	4	no	65.932	68.325	EPSD	COSMIC	56.683	Up-regulation
CAMK_CAMKL_AMPK_PRKAA1_ST	P41235	HNF4A	Q13131	PRKAA1	T166	R163G	163	Missense	distal	-3	no	65.932	56.897	EPSD	COSMIC	56.683	Down-regulation
CAMK_CAMKL_AMPK_PRKAA1_ST	P41235	HNF4A	Q13131	PRKAA1	T166	R163Q	163	Missense	distal	-3	no	65.932	57.988	EPSD	COSMIC	56.683	Down-regulation
CAMK_CAMKL_AMPK_PRKAA1_ST	P41235	HNF4A	Q13131	PRKAA1	S170	Q164H	164	Missense	distal	-6	no	56.727	54.836	EPSD	COSMIC	56.683	Loss
CAMK_CAMKL_AMPK_PRKAA1_ST	P41235	HNF4A	Q13131	PRKAA1	S170	G171R	171	Missense	proximal	1	no	56.727	55.153	EPSD	COSMIC	56.683	Loss
CAMK_CAMKL_AMPK_PRKAA1_ST	P41235	HNF4A	Q13131	PRKAA1	S170	R177Q	177	Missense	distal	7	no	56.727	58.091	EPSD	COSMIC;GDSC	56.683	Up-regulation
CAMK_CAMKL_AMPK_PRKAA1_ST	P41235	HNF4A	Q13131	PRKAA1	S170	P168T	168	Missense	proximal	-2	no	56.727	53.496	EPSD	COSMIC	56.683	Loss
CAMK_CAMKL_AMPK_PRKAA1_ST	P41235	HNF4A	Q13131	PRKAA1	S170	S170F	170	Missense	central	0	yes	56.727	0.000	EPSD	COSMIC	56.683	Loss
CAMK_CAMKL_AMPK_PRKAA1_ST	P41235	HNF4A	Q13131	PRKAA1	S170	R163G	163	Missense	distal	-7	no	56.727	58.143	EPSD	COSMIC	56.683	Up-regulation
CAMK_CAMKL_AMPK_PRKAA1_ST	P41235	HNF4A	Q13131	PRKAA1	S170	R163Q	163	Missense	distal	-7	no	56.727	56.904	EPSD	COSMIC	56.683	Up-regulation
CAMK_CAMKL_AMPK_PRKAA1_ST	P41235	HNF4A	Q13131	PRKAA1	S170	G174D	174	Missense	distal	4	no	56.727	57.085	EPSD	COSMIC	56.683	Up-regulation
CAMK_CAMKL_AMPK_PRKAA1_ST	P41235	HNF4A	Q13131	PRKAA1	S303	D296N	296	Missense	distal	-7	no	58.110	57.904	EPSD	COSMIC	56.683	Down-regulation
CAMK_CAMKL_AMPK_PRKAA1_ST	P41235	HNF4A	Q13131	PRKAA1	S303	D304E	304	Missense	proximal	1	no	58.110	57.898	EPSD	COSMIC	56.683	Down-regulation
CAMK_CAMKL_AMPK_PRKAA1_ST	P41235	HNF4A	Q13131	PRKAA1	S303	D298V	298	Missense	distal	-5	no	58.110	58.281	EPSD	COSMIC	56.683	Up-regulation
CAMK_CAMKL_AMPK_PRKAA1_ST	P41235	HNF4A	Q13131	PRKAA1	S313	L319P	319	Missense	distal	6	no	57.846	57.697	PhosphoSitePlus	COSMIC	56.683	Down-regulation
CAMK_CAMKL_AMPK_PRKAA1_ST	P41235	HNF4A	Q13131	PRKAA1	T429	A427D	427	Missense	proximal	-2	no	56.583	56.895	EPSD	COSMIC	56.683	Gain
CAMK_CAMKL_AMPK_PRKAA1_ST	P41235	HNF4A	Q13131	PRKAA1	T429	G425E	425	Missense	distal	-4	no	56.583	60.135	EPSD	COSMIC	56.683	Gain
CAMK_CAMKL_AMPK_PRKAA1_ST	P41235	HNF4A	Q13131	PRKAA1	T429	P430S	430	Missense	proximal	1	no	56.583	57.215	EPSD	COSMIC	56.683	Gain
CAMK_CAMKL_AMPK_PRKAA1_ST	P41235	HNF4A	Q13131	PRKAA1	T429	P423T	423	Missense	distal	-6	no	56.583	56.699	EPSD	COSMIC	56.683	Gain
CAMK_CAMKL_AMPK_PRKAA1_ST	P41235	HNF4A	Q13131	PRKAA1	S443	G439C	439	Missense	distal	-4	no	51.166	59.084	EPSD	COSMIC	56.683	Gain
CAMK_CAMKL_AMPK_PRKAA1_ST	P49674	CSNK1E	Q13131	PRKAA1	S234	T235M	235	Missense	proximal	1	no	56.092	59.177	EPSD	COSMIC	56.683	Gain
CAMK_CAMKL_AMPK_PRKAA1_ST	P49674	CSNK1E	Q13131	PRKAA1	S234	E238D	238	Missense	distal	4	no	56.092	60.008	EPSD	COSMIC	56.683	Gain
CAMK_CAMKL_AMPK_PRKAA1_ST	P49674	CSNK1E	Q13131	PRKAA1	T250	C255W	255	Missense	distal	5	no	60.708	60.579	EPSD	COSMIC	56.683	Down-regulation
CAMK_CAMKL_AMPK_PRKAA1_ST	P49674	CSNK1E	Q13131	PRKAA1	T250	R256L	256	Missense	distal	6	no	60.708	60.949	EPSD	COSMIC;GDSC;CCLE	56.683	Up-regulation
CAMK_CAMKL_AMPK_PRKAA1_ST	P49674	CSNK1E	Q13131	PRKAA1	S368	S363F	363	Missense	distal	-5	no	60.311	58.969	EPSD	COSMIC	56.683	Down-regulation
CAMK_CAMKL_AMPK_PRKAA1_ST	P49674	CSNK1E	Q13131	PRKAA1	S368	D371N	371	Missense	distal	3	no	60.311	61.564	EPSD	COSMIC	56.683	Up-regulation
CAMK_CAMKL_AMPK_PRKAA1_ST	P49674	CSNK1E	Q13131	PRKAA1	S377	D371N	371	Missense	distal	-6	no	60.788	58.523	EPSD	COSMIC	56.683	Down-regulation
CAMK_CAMKL_AMPK_PRKAA1_ST	P49674	CSNK1E	Q13131	PRKAA1	S389	S390F	390	Missense	proximal	1	no	66.528	71.068	PhosphoSitePlus	COSMIC	56.683	Up-regulation
CAMK_CAMKL_AMPK_PRKAA1_ST	P49674	CSNK1E	Q13131	PRKAA1	S390	S390F	390	Missense	central	0	yes	63.455	0.000	EPSD	COSMIC	56.683	Loss
CAMK_CAMKL_AMPK_PRKAA1_ST	P49674	CSNK1E	Q13131	PRKAA1	T407	P410L	410	Missense	distal	3	no	57.400	57.656	EPSD	COSMIC	56.683	Up-regulation
CAMK_CAMKL_AMPK_PRKAA1_ST	P49674	CSNK1E	Q13131	PRKAA1	T407	P403S	403	Missense	distal	-4	no	57.400	58.644	EPSD	COSMIC	56.683	Up-regulation
CAMK_CAMKL_AMPK_PRKAA1_ST	P04626	ERBB2	Q13131	PRKAA1	S196	S189C	189	Missense	distal	-7	no	64.227	61.838	EPSD	COSMIC	56.683	Down-regulation
CAMK_CAMKL_AMPK_PRKAA1_ST	P04626	ERBB2	Q13131	PRKAA1	S196	C195Y	195	Missense	proximal	-1	no	64.227	64.226	EPSD	COSMIC	56.683	Down-regulation
CAMK_CAMKL_AMPK_PRKAA1_ST	P04626	ERBB2	Q13131	PRKAA1	S196	P197L	197	Missense	proximal	1	no	64.227	63.934	EPSD	COSMIC	56.683	Down-regulation
CAMK_CAMKL_AMPK_PRKAA1_ST	P04626	ERBB2	Q13131	PRKAA1	S196	P197S	197	Missense	proximal	1	no	64.227	64.859	EPSD	COSMIC	56.683	Up-regulation
CAMK_CAMKL_AMPK_PRKAA1_ST	P04626	ERBB2	Q13131	PRKAA1	S196	G201V	201	Missense	distal	5	no	64.227	64.217	EPSD	COSMIC	56.683	Down-regulation
CAMK_CAMKL_AMPK_PRKAA1_ST	P04626	ERBB2	Q13131	PRKAA1	S196	K200N	200	Missense	distal	4	no	64.227	61.654	EPSD	COSMIC	56.683	Down-regulation
CAMK_CAMKL_AMPK_PRKAA1_ST	P04626	ERBB2	Q13131	PRKAA1	S196	S196P	196	Missense	central	0	yes	64.227	0.000	EPSD	COSMIC	56.683	Loss
CAMK_CAMKL_AMPK_PRKAA1_ST	P04626	ERBB2	Q13131	PRKAA1	S196	R190L	190	Missense	distal	-6	no	64.227	64.066	EPSD	COSMIC	56.683	Down-regulation
CAMK_CAMKL_AMPK_PRKAA1_ST	P04626	ERBB2	Q13131	PRKAA1	S196	R190Q	190	Missense	distal	-6	no	64.227	64.584	EPSD	COSMIC	56.683	Up-regulation
CAMK_CAMKL_AMPK_PRKAA1_ST	P04626	ERBB2	Q13131	PRKAA1	S196	M198T	198	Missense	proximal	2	no	64.227	64.379	EPSD	COSMIC	56.683	Up-regulation
CAMK_CAMKL_AMPK_PRKAA1_ST	P04626	ERBB2	Q13131	PRKAA1	S196	A191P	191	Missense	distal	-5	no	64.227	63.157	EPSD	COSMIC	56.683	Down-regulation
CAMK_CAMKL_AMPK_PRKAA1_ST	P04626	ERBB2	Q13131	PRKAA1	S196	K200R	200	Missense	distal	4	no	64.227	64.230	EPSD	COSMIC	56.683	Up-regulation
CAMK_CAMKL_AMPK_PRKAA1_ST	P04626	ERBB2	Q13131	PRKAA1	S196	A191V	191	Missense	distal	-5	no	64.227	63.034	EPSD	COSMIC	56.683	Down-regulation
CAMK_CAMKL_AMPK_PRKAA1_ST	P04626	ERBB2	Q13131	PRKAA1	S196	A191S	191	Missense	distal	-5	no	64.227	63.715	EPSD	COSMIC	56.683	Down-regulation
CAMK_CAMKL_AMPK_PRKAA1_ST	P04626	ERBB2	Q13131	PRKAA1	T686	R683G	683	Missense	distal	-3	no	58.408	49.372	EPSD	COSMIC	56.683	Loss
CAMK_CAMKL_AMPK_PRKAA1_ST	P04626	ERBB2	Q13131	PRKAA1	T686	R683Q	683	Missense	distal	-3	no	58.408	50.463	EPSD	COSMIC	56.683	Loss
CAMK_CAMKL_AMPK_PRKAA1_ST	P04626	ERBB2	Q13131	PRKAA1	T686	R688W	688	Missense	proximal	2	no	58.408	58.492	EPSD	COSMIC	56.683	Up-regulation
CAMK_CAMKL_AMPK_PRKAA1_ST	P04626	ERBB2	Q13131	PRKAA1	T686	Q680H	680	Missense	distal	-6	no	58.408	56.516	EPSD	COSMIC	56.683	Loss
CAMK_CAMKL_AMPK_PRKAA1_ST	P04626	ERBB2	Q13131	PRKAA1	T686	Q679L	679	Missense	distal	-7	no	58.408	56.798	EPSD	COSMIC	56.683	Down-regulation
CAMK_CAMKL_AMPK_PRKAA1_ST	P04626	ERBB2	Q13131	PRKAA1	T686	E693K	693	Missense	distal	7	no	58.408	57.711	EPSD	COSMIC	56.683	Down-regulation
CAMK_CAMKL_AMPK_PRKAA1_ST	P04626	ERBB2	Q13131	PRKAA1	T686	T686R	686	Missense	central	0	yes	58.408	0.000	EPSD	COSMIC;CCLE	56.683	Loss
CAMK_CAMKL_AMPK_PRKAA1_ST	P04626	ERBB2	Q13131	PRKAA1	T686	L690P	690	Missense	distal	4	no	58.408	51.668	EPSD	COSMIC	56.683	Loss
CAMK_CAMKL_AMPK_PRKAA1_ST	P04626	ERBB2	Q13131	PRKAA1	T686	R683W	683	Missense	distal	-3	no	58.408	-34.592	EPSD	COSMIC	56.683	Loss
CAMK_CAMKL_AMPK_PRKAA1_ST	P04626	ERBB2	Q13131	PRKAA1	T701	E698K	698	Missense	distal	-3	no	53.987	57.827	EPSD	COSMIC	56.683	Gain
CAMK_CAMKL_AMPK_PRKAA1_ST	P04626	ERBB2	Q13131	PRKAA1	S760	V754M	754	Missense	distal	-6	no	58.153	58.495	EPSD	COSMIC	56.683	Up-regulation
CAMK_CAMKL_AMPK_PRKAA1_ST	P04626	ERBB2	Q13131	PRKAA1	S760	L755A	755	Missense	distal	-5	no	58.153	54.482	EPSD	COSMIC	56.683	Loss
CAMK_CAMKL_AMPK_PRKAA1_ST	P04626	ERBB2	Q13131	PRKAA1	S760	L755P	755	Missense	distal	-5	no	58.153	53.413	EPSD	COSMIC	56.683	Loss
CAMK_CAMKL_AMPK_PRKAA1_ST	P04626	ERBB2	Q13131	PRKAA1	S760	S760F	760	Missense	central	0	yes	58.153	0.000	EPSD	COSMIC	56.683	Loss
CAMK_CAMKL_AMPK_PRKAA1_ST	P04626	ERBB2	Q13131	PRKAA1	S760	E757K	757	Missense	distal	-3	no	58.153	61.994	EPSD	COSMIC	56.683	Up-regulation
CAMK_CAMKL_AMPK_PRKAA1_ST	P04626	ERBB2	Q13131	PRKAA1	S760	E757D	757	Missense	distal	-3	no	58.153	56.782	EPSD	COSMIC	56.683	Down-regulation
CAMK_CAMKL_AMPK_PRKAA1_ST	P04626	ERBB2	Q13131	PRKAA1	S760	S760P	760	Missense	central	0	yes	58.153	0.000	EPSD	COSMIC	56.683	Loss
CAMK_CAMKL_AMPK_PRKAA1_ST	P04626	ERBB2	Q13131	PRKAA1	S760	P761L	761	Missense	proximal	1	no	58.153	57.860	EPSD	COSMIC	56.683	Down-regulation
CAMK_CAMKL_AMPK_PRKAA1_ST	P04626	ERBB2	Q13131	PRKAA1	S760	L755R	755	Missense	distal	-5	no	58.153	56.976	EPSD	COSMIC	56.683	Down-regulation
CAMK_CAMKL_AMPK_PRKAA1_ST	P04626	ERBB2	Q13131	PRKAA1	S760	L755F	755	Missense	distal	-5	no	58.153	52.629	EPSD	COSMIC	56.683	Loss
CAMK_CAMKL_AMPK_PRKAA1_ST	P04626	ERBB2	Q13131	PRKAA1	S819	G815R	815	Missense	distal	-4	no	56.652	60.259	EPSD	COSMIC	56.683	Gain
CAMK_CAMKL_AMPK_PRKAA1_ST	P04626	ERBB2	Q13131	PRKAA1	T875	H878Y	878	Missense	distal	3	no	53.064	58.202	EPSD	COSMIC	56.683	Gain
CAMK_CAMKL_AMPK_PRKAA1_ST	P04626	ERBB2	Q13131	PRKAA1	T900	R896C	896	Missense	distal	-4	no	66.903	71.214	PhosphoSitePlus	COSMIC	56.683	Up-regulation
CAMK_CAMKL_AMPK_PRKAA1_ST	P04626	ERBB2	Q13131	PRKAA1	T900	W906C	906	Missense	distal	6	no	66.903	67.724	PhosphoSitePlus	COSMIC	56.683	Up-regulation
CAMK_CAMKL_AMPK_PRKAA1_ST	P04626	ERBB2	Q13131	PRKAA1	T900	Q902H	902	Missense	proximal	2	no	66.903	67.675	PhosphoSitePlus	COSMIC	56.683	Up-regulation
CAMK_CAMKL_AMPK_PRKAA1_ST	P04626	ERBB2	Q13131	PRKAA1	T900	F899L	899	Missense	proximal	-1	no	66.903	66.974	PhosphoSitePlus	COSMIC	56.683	Up-regulation
CAMK_CAMKL_AMPK_PRKAA1_ST	P04626	ERBB2	Q13131	PRKAA1	T900	R897W	897	Missense	distal	-3	no	66.903	-26.097	PhosphoSitePlus	COSMIC	56.683	Loss
CAMK_CAMKL_AMPK_PRKAA1_ST	P04626	ERBB2	Q13131	PRKAA1	T900	I894L	894	Missense	distal	-6	no	66.903	69.887	PhosphoSitePlus	COSMIC	56.683	Up-regulation
CAMK_CAMKL_AMPK_PRKAA1_ST	P04626	ERBB2	Q13131	PRKAA1	T900	R896H	896	Missense	distal	-4	no	66.903	63.516	PhosphoSitePlus	COSMIC;CCLE	56.683	Down-regulation
CAMK_CAMKL_AMPK_PRKAA1_ST	P04626	ERBB2	Q13131	PRKAA1	T900	R897G	897	Missense	distal	-3	no	66.903	57.867	PhosphoSitePlus	COSMIC	56.683	Down-regulation
CAMK_CAMKL_AMPK_PRKAA1_ST	P04626	ERBB2	Q13131	PRKAA1	T900	L895F	895	Missense	distal	-5	no	66.903	61.379	PhosphoSitePlus	COSMIC	56.683	Down-regulation
CAMK_CAMKL_AMPK_PRKAA1_ST	P04626	ERBB2	Q13131	PRKAA1	S974	R970C	970	Missense	distal	-4	no	52.375	56.686	EPSD	COSMIC	56.683	Gain
CAMK_CAMKL_AMPK_PRKAA1_ST	P04626	ERBB2	Q13131	PRKAA1	S1051	S1049I	1049	Missense	proximal	-2	no	60.932	59.054	EPSD	COSMIC	56.683	Down-regulation
CAMK_CAMKL_AMPK_PRKAA1_ST	P04626	ERBB2	Q13131	PRKAA1	S1051	S1051F	1051	Missense	central	0	yes	60.932	0.000	EPSD	COSMIC	56.683	Loss
CAMK_CAMKL_AMPK_PRKAA1_ST	P04626	ERBB2	Q13131	PRKAA1	S1051	S1050L	1050	Missense	proximal	-1	no	60.932	60.957	EPSD	COSMIC;GDSC	56.683	Up-regulation
CAMK_CAMKL_AMPK_PRKAA1_ST	P04626	ERBB2	Q13131	PRKAA1	S1051	D1058A	1058	Missense	distal	7	no	60.932	62.279	EPSD	COSMIC	56.683	Up-regulation
CAMK_CAMKL_AMPK_PRKAA1_ST	P04626	ERBB2	Q13131	PRKAA1	S1051	D1058N	1058	Missense	distal	7	no	60.932	62.453	EPSD	COSMIC	56.683	Up-regulation
CAMK_CAMKL_AMPK_PRKAA1_ST	P04626	ERBB2	Q13131	PRKAA1	S1051	G1056S	1056	Missense	distal	5	no	60.932	60.976	EPSD	COSMIC	56.683	Up-regulation
CAMK_CAMKL_AMPK_PRKAA1_ST	P04626	ERBB2	Q13131	PRKAA1	S1051	G1056D	1056	Missense	distal	5	no	60.932	61.083	EPSD	COSMIC	56.683	Up-regulation
CAMK_CAMKL_AMPK_PRKAA1_ST	P04626	ERBB2	Q13131	PRKAA1	S1051	G1056C	1056	Missense	distal	5	no	60.932	61.011	EPSD	COSMIC	56.683	Up-regulation
CAMK_CAMKL_AMPK_PRKAA1_ST	P04626	ERBB2	Q13131	PRKAA1	S1054	S1049I	1049	Missense	distal	-5	no	54.046	58.807	EPSD	COSMIC	56.683	Gain
CAMK_CAMKL_AMPK_PRKAA1_ST	P04626	ERBB2	Q13131	PRKAA1	S1054	D1058A	1058	Missense	distal	4	no	54.046	56.840	EPSD	COSMIC	56.683	Gain
CAMK_CAMKL_AMPK_PRKAA1_ST	P04626	ERBB2	Q13131	PRKAA1	S1066	E1064K	1064	Missense	proximal	-2	no	55.767	57.042	EPSD	COSMIC	56.683	Gain
CAMK_CAMKL_AMPK_PRKAA1_ST	P04626	ERBB2	Q13131	PRKAA1	T1166	L1167F	1167	Missense	proximal	1	no	53.075	58.541	EPSD	COSMIC	56.683	Gain
CAMK_CAMKL_AMPK_PRKAA1_ST	P04626	ERBB2	Q13131	PRKAA1	T1172	L1173P	1173	Missense	proximal	1	no	56.626	56.919	EPSD	COSMIC	56.683	Gain
CAMK_CAMKL_AMPK_PRKAA1_ST	P04626	ERBB2	Q13131	PRKAA1	T1172	G1176W	1176	Missense	distal	4	no	56.626	62.078	EPSD	COSMIC	56.683	Gain
CAMK_CAMKL_AMPK_PRKAA1_ST	P04626	ERBB2	Q13131	PRKAA1	T1172	K1171M	1171	Missense	proximal	-1	no	56.626	56.749	EPSD	COSMIC	56.683	Gain
CAMK_CAMKL_AMPK_PRKAA1_ST	P04626	ERBB2	Q13131	PRKAA1	T1172	P1175R	1175	Missense	distal	3	no	56.626	58.213	EPSD	COSMIC	56.683	Gain
CAMK_CAMKL_AMPK_PRKAA1_ST	P04626	ERBB2	Q13131	PRKAA1	S1174	P1170A	1170	Missense	distal	-4	no	56.457	57.300	EPSD	COSMIC	56.683	Gain
CAMK_CAMKL_AMPK_PRKAA1_ST	P04626	ERBB2	Q13131	PRKAA1	S1174	G1176W	1176	Missense	proximal	2	no	56.457	57.145	EPSD	COSMIC	56.683	Gain
CAMK_CAMKL_AMPK_PRKAA1_ST	P04626	ERBB2	Q13131	PRKAA1	S1174	L1167V	1167	Missense	distal	-7	no	56.457	57.506	EPSD	COSMIC	56.683	Gain
CAMK_CAMKL_AMPK_PRKAA1_ST	Q14694	USP10	Q13131	PRKAA1	S35	G41D	41	Missense	distal	6	no	68.183	68.111	EPSD	COSMIC	56.683	Down-regulation
CAMK_CAMKL_AMPK_PRKAA1_ST	Q14694	USP10	Q13131	PRKAA1	S35	L39V	39	Missense	distal	4	no	68.183	63.685	EPSD	COSMIC	56.683	Down-regulation
CAMK_CAMKL_AMPK_PRKAA1_ST	Q14694	USP10	Q13131	PRKAA1	S109	G103C	103	Missense	distal	-6	no	58.285	55.173	EPSD	COSMIC	56.683	Loss
CAMK_CAMKL_AMPK_PRKAA1_ST	Q14694	USP10	Q13131	PRKAA1	S109	T105S	105	Missense	distal	-4	no	58.285	59.541	EPSD	COSMIC;GDSC;CCLE	56.683	Up-regulation
CAMK_CAMKL_AMPK_PRKAA1_ST	Q14694	USP10	Q13131	PRKAA1	S218	D221N	221	Missense	distal	3	no	57.112	58.365	EPSD	COSMIC	56.683	Up-regulation
CAMK_CAMKL_AMPK_PRKAA1_ST	Q14694	USP10	Q13131	PRKAA1	S218	D217N	217	Missense	proximal	-1	no	57.112	57.071	EPSD	COSMIC	56.683	Down-regulation
CAMK_CAMKL_AMPK_PRKAA1_ST	Q14694	USP10	Q13131	PRKAA1	S218	T216S	216	Missense	proximal	-2	no	57.112	59.794	EPSD	COSMIC;GDSC;CCLE	56.683	Up-regulation
CAMK_CAMKL_AMPK_PRKAA1_ST	Q14694	USP10	Q13131	PRKAA1	S331	D325E	325	Missense	distal	-6	no	57.713	53.946	EPSD	COSMIC	56.683	Loss
CAMK_CAMKL_AMPK_PRKAA1_ST	Q14694	USP10	Q13131	PRKAA1	S331	A330S	330	Missense	proximal	-1	no	57.713	57.691	EPSD	COSMIC	56.683	Down-regulation
CAMK_CAMKL_AMPK_PRKAA1_ST	Q14694	USP10	Q13131	PRKAA1	S331	G332V	332	Missense	proximal	1	no	57.713	56.989	EPSD	COSMIC	56.683	Down-regulation
CAMK_CAMKL_AMPK_PRKAA1_ST	Q14694	USP10	Q13131	PRKAA1	S352	P356L	356	Missense	distal	4	no	53.586	60.326	EPSD	COSMIC	56.683	Gain
CAMK_CAMKL_AMPK_PRKAA1_ST	Q14694	USP10	Q13131	PRKAA1	S354	E361A	361	Missense	distal	7	no	56.944	57.849	EPSD	COSMIC	56.683	Up-regulation
CAMK_CAMKL_AMPK_PRKAA1_ST	Q14694	USP10	Q13131	PRKAA1	S354	S349Y	349	Missense	distal	-5	no	56.944	56.089	EPSD	COSMIC	56.683	Loss
CAMK_CAMKL_AMPK_PRKAA1_ST	Q14694	USP10	Q13131	PRKAA1	S354	P356L	356	Missense	proximal	2	no	56.944	56.344	EPSD	COSMIC	56.683	Loss
CAMK_CAMKL_AMPK_PRKAA1_ST	P22460	KCNA5	Q13131	PRKAA1	S559	F563L	563	Missense	distal	4	no	57.162	61.357	PhosphoSitePlus	COSMIC	56.683	Up-regulation
CAMK_CAMKL_AMPK_PRKAA1_ST	P22460	KCNA5	Q13131	PRKAA1	S559	Q553H	553	Missense	distal	-6	no	57.162	55.271	PhosphoSitePlus	COSMIC	56.683	Loss
CAMK_CAMKL_AMPK_PRKAA1_ST	Q9BUB5	MKNK1	Q13131	PRKAA1	S237	D232Y	232	Missense	distal	-5	no	58.332	58.330	EPSD	COSMIC	56.683	Down-regulation
CAMK_CAMKL_AMPK_PRKAA1_ST	Q9BUB5	MKNK1	Q13131	PRKAA1	S237	D234V	234	Missense	distal	-3	no	58.332	59.770	EPSD	COSMIC	56.683	Up-regulation
CAMK_CAMKL_AMPK_PRKAA1_ST	Q9BUB5	MKNK1	Q13131	PRKAA1	S237	S244Y	244	Missense	distal	7	no	58.332	58.581	EPSD	COSMIC	56.683	Up-regulation
CAMK_CAMKL_AMPK_PRKAA1_ST	Q9BUB5	MKNK1	Q13131	PRKAA1	S433	L431P	431	Missense	proximal	-2	no	55.591	58.565	EPSD	COSMIC	56.683	Gain
CAMK_CAMKL_AMPK_PRKAA1_ST	Q9BUB5	MKNK1	Q13131	PRKAA1	S437	L431P	431	Missense	distal	-6	no	60.055	60.095	EPSD	COSMIC	56.683	Up-regulation
CAMK_CAMKL_AMPK_PRKAA1_ST	Q9BUB5	MKNK1	Q13131	PRKAA1	S437	K435N	435	Missense	proximal	-2	no	60.055	59.257	EPSD	COSMIC	56.683	Down-regulation
CAMK_CAMKL_AMPK_PRKAA1_ST	Q9BUB5	MKNK1	Q13131	PRKAA1	S437	C440F	440	Missense	distal	3	no	60.055	60.678	EPSD	COSMIC;GDSC;CCLE	56.683	Up-regulation
CAMK_CAMKL_AMPK_PRKAA1_ST	Q9NRC8	SIRT7	Q13131	PRKAA1	S94	G87W	87	Missense	distal	-7	no	56.718	57.101	EPSD	COSMIC	56.683	Up-regulation
CAMK_CAMKL_AMPK_PRKAA1_ST	Q9NRC8	SIRT7	Q13131	PRKAA1	S94	A95T	95	Missense	proximal	1	no	56.718	57.271	EPSD	COSMIC	56.683	Up-regulation
CAMK_CAMKL_AMPK_PRKAA1_ST	O15360	FANCA	Q13131	PRKAA1	S73	D79V	79	Missense	distal	6	no	60.311	60.500	EPSD	COSMIC	56.683	Up-regulation
CAMK_CAMKL_AMPK_PRKAA1_ST	O15360	FANCA	Q13131	PRKAA1	S73	K70N	70	Missense	distal	-3	no	60.311	59.016	EPSD	COSMIC	56.683	Down-regulation
CAMK_CAMKL_AMPK_PRKAA1_ST	O15360	FANCA	Q13131	PRKAA1	S73	K71N	71	Missense	proximal	-2	no	60.311	59.513	EPSD	COSMIC	56.683	Down-regulation
CAMK_CAMKL_AMPK_PRKAA1_ST	O15360	FANCA	Q13131	PRKAA1	S73	L72M	72	Missense	proximal	-1	no	60.311	60.303	EPSD	COSMIC	56.683	Down-regulation
CAMK_CAMKL_AMPK_PRKAA1_ST	O15360	FANCA	Q13131	PRKAA1	S73	S75I	75	Missense	proximal	2	no	60.311	59.699	EPSD	COSMIC	56.683	Down-regulation
CAMK_CAMKL_AMPK_PRKAA1_ST	O15360	FANCA	Q13131	PRKAA1	S73	G66C	66	Missense	distal	-7	no	60.311	57.504	EPSD	COSMIC	56.683	Down-regulation
CAMK_CAMKL_AMPK_PRKAA1_ST	O15360	FANCA	Q13131	PRKAA1	S347	R350Q	350	Missense	distal	3	no	62.410	63.803	PhosphoSitePlus	COSMIC;GDSC	56.683	Up-regulation
CAMK_CAMKL_AMPK_PRKAA1_ST	O15360	FANCA	Q13131	PRKAA1	S347	W346C	346	Missense	proximal	-1	no	62.410	62.469	PhosphoSitePlus	COSMIC	56.683	Up-regulation
CAMK_CAMKL_AMPK_PRKAA1_ST	O15360	FANCA	Q13131	PRKAA1	S347	M342I	342	Missense	distal	-5	no	62.410	63.156	PhosphoSitePlus	COSMIC	56.683	Up-regulation
CAMK_CAMKL_AMPK_PRKAA1_ST	O15360	FANCA	Q13131	PRKAA1	T351	W346C	346	Missense	distal	-5	no	54.675	58.515	EPSD	COSMIC	56.683	Gain
CAMK_CAMKL_AMPK_PRKAA1_ST	O15360	FANCA	Q13131	PRKAA1	S391	L390I	390	Missense	proximal	-1	no	60.490	60.479	EPSD	COSMIC	56.683	Down-regulation
CAMK_CAMKL_AMPK_PRKAA1_ST	O15360	FANCA	Q13131	PRKAA1	S850	R853Q	853	Missense	distal	3	no	59.552	60.946	EPSD	COSMIC;CCLE	56.683	Up-regulation
CAMK_CAMKL_AMPK_PRKAA1_ST	O15360	FANCA	Q13131	PRKAA1	S850	K847N	847	Missense	distal	-3	no	59.552	58.257	EPSD	COSMIC	56.683	Down-regulation
CAMK_CAMKL_AMPK_PRKAA1_ST	O15360	FANCA	Q13131	PRKAA1	S850	K847Q	847	Missense	distal	-3	no	59.552	56.249	EPSD	COSMIC	56.683	Loss
CAMK_CAMKL_AMPK_PRKAA1_ST	O15360	FANCA	Q13131	PRKAA1	S1301	I1300M	1300	Missense	proximal	-1	no	56.946	56.949	EPSD	COSMIC	56.683	Up-regulation
CAMK_CAMKL_AMPK_PRKAA1_ST	O15360	FANCA	Q13131	PRKAA1	S1301	K1299N	1299	Missense	proximal	-2	no	56.946	56.148	EPSD	COSMIC	56.683	Loss
CAMK_CAMKL_AMPK_PRKAA1_ST	O95239	KIF4A	Q13131	PRKAA1	T500	R506K	506	Missense	distal	6	no	57.122	57.174	EPSD	COSMIC	56.683	Up-regulation
CAMK_CAMKL_AMPK_PRKAA1_ST	O95239	KIF4A	Q13131	PRKAA1	T500	E495K	495	Missense	distal	-5	no	57.122	54.474	EPSD	COSMIC	56.683	Loss
CAMK_CAMKL_AMPK_PRKAA1_ST	O95239	KIF4A	Q13131	PRKAA1	S787	P793S	793	Missense	distal	6	no	57.804	57.820	EPSD	COSMIC	56.683	Up-regulation
CAMK_CAMKL_AMPK_PRKAA1_ST	O95239	KIF4A	Q13131	PRKAA1	T799	R806H	806	Missense	distal	7	no	56.949	56.222	EPSD	COSMIC	56.683	Loss
CAMK_CAMKL_AMPK_PRKAA1_ST	O95239	KIF4A	Q13131	PRKAA1	T799	P793S	793	Missense	distal	-6	no	56.949	56.599	EPSD	COSMIC	56.683	Loss
CAMK_CAMKL_AMPK_PRKAA1_ST	O95239	KIF4A	Q13131	PRKAA1	T799	R798H	798	Missense	proximal	-1	no	56.949	56.968	EPSD	COSMIC	56.683	Up-regulation
CAMK_CAMKL_AMPK_PRKAA1_ST	O95239	KIF4A	Q13131	PRKAA1	T799	S801F	801	Missense	proximal	2	no	56.949	56.656	EPSD	COSMIC	56.683	Loss
CAMK_CAMKL_AMPK_PRKAA1_ST	O95239	KIF4A	Q13131	PRKAA1	T799	R798Q	798	Missense	proximal	-1	no	56.949	56.977	EPSD	COSMIC	56.683	Up-regulation
CAMK_CAMKL_AMPK_PRKAA1_ST	O95239	KIF4A	Q13131	PRKAA1	S801	R806H	806	Missense	distal	5	no	69.354	69.162	PhosphoSitePlus	COSMIC	56.683	Down-regulation
CAMK_CAMKL_AMPK_PRKAA1_ST	O95239	KIF4A	Q13131	PRKAA1	S801	R798H	798	Missense	distal	-3	no	69.354	61.498	PhosphoSitePlus	COSMIC	56.683	Down-regulation
CAMK_CAMKL_AMPK_PRKAA1_ST	O95239	KIF4A	Q13131	PRKAA1	S801	S801F	801	Missense	central	0	yes	69.354	0.000	PhosphoSitePlus	COSMIC	56.683	Loss
CAMK_CAMKL_AMPK_PRKAA1_ST	O95239	KIF4A	Q13131	PRKAA1	S801	R798Q	798	Missense	distal	-3	no	69.354	61.410	PhosphoSitePlus	COSMIC	56.683	Down-regulation
CAMK_CAMKL_AMPK_PRKAA1_ST	O95239	KIF4A	Q13131	PRKAA1	S1017	P1014S	1014	Missense	distal	-3	no	61.038	60.503	EPSD	COSMIC	56.683	Down-regulation
CAMK_CAMKL_AMPK_PRKAA1_ST	O95239	KIF4A	Q13131	PRKAA1	S1048	E1042K	1042	Missense	distal	-6	no	58.577	58.947	EPSD	COSMIC	56.683	Up-regulation
CAMK_CAMKL_AMPK_PRKAA1_ST	O95239	KIF4A	Q13131	PRKAA1	S1186	L1190F	1190	Missense	distal	4	no	58.170	53.975	EPSD	COSMIC;GDSC;CCLE	56.683	Loss
CAMK_CAMKL_AMPK_PRKAA1_ST	O95239	KIF4A	Q13131	PRKAA1	S1186	P1187H	1187	Missense	proximal	1	no	58.170	60.813	EPSD	COSMIC	56.683	Up-regulation
CAMK_CAMKL_AMPK_PRKAA1_ST	O95239	KIF4A	Q13131	PRKAA1	S1186	S1186F	1186	Missense	central	0	yes	58.170	0.000	EPSD	COSMIC;GDSC;CCLE	56.683	Loss
CAMK_CAMKL_AMPK_PRKAA1_ST	O75385	ULK1	Q13131	PRKAA1	S317	L318M	318	Missense	proximal	1	no	64.086	67.054	EPSD	COSMIC	56.683	Up-regulation
CAMK_CAMKL_AMPK_PRKAA1_ST	O75385	ULK1	Q13131	PRKAA1	S347	T354I	354	Missense	distal	7	no	57.105	56.259	EPSD	COSMIC	56.683	Loss
CAMK_CAMKL_AMPK_PRKAA1_ST	O75385	ULK1	Q13131	PRKAA1	S424	G427D	427	Missense	distal	3	no	57.223	56.761	EPSD	COSMIC	56.683	Down-regulation
CAMK_CAMKL_AMPK_PRKAA1_ST	O75385	ULK1	Q13131	PRKAA1	S424	A428T	428	Missense	distal	4	no	57.223	54.655	EPSD	COSMIC;CCLE	56.683	Loss
CAMK_CAMKL_AMPK_PRKAA1_ST	O75385	ULK1	Q13131	PRKAA1	S467	R463C	463	Missense	distal	-4	no	72.895	77.206	EPSD	COSMIC	56.683	Up-regulation
CAMK_CAMKL_AMPK_PRKAA1_ST	O75385	ULK1	Q13131	PRKAA1	S467	R463L	463	Missense	distal	-4	no	72.895	70.335	EPSD	COSMIC	56.683	Down-regulation
CAMK_CAMKL_AMPK_PRKAA1_ST	O75385	ULK1	Q13131	PRKAA1	S469	R463C	463	Missense	distal	-6	no	62.045	57.968	EPSD	COSMIC	56.683	Down-regulation
CAMK_CAMKL_AMPK_PRKAA1_ST	O75385	ULK1	Q13131	PRKAA1	S469	R463L	463	Missense	distal	-6	no	62.045	61.884	EPSD	COSMIC	56.683	Down-regulation
CAMK_CAMKL_AMPK_PRKAA1_ST	O75385	ULK1	Q13131	PRKAA1	S538	P541H	541	Missense	distal	3	no	59.648	57.667	EPSD	COSMIC	56.683	Down-regulation
CAMK_CAMKL_AMPK_PRKAA1_ST	O75385	ULK1	Q13131	PRKAA1	S544	P541H	541	Missense	distal	-3	no	55.842	56.846	EPSD	COSMIC	56.683	Gain
CAMK_CAMKL_AMPK_PRKAA1_ST	O75385	ULK1	Q13131	PRKAA1	S556	R553C	553	Missense	distal	-3	no	75.749	61.602	EPSD	COSMIC	56.683	Down-regulation
CAMK_CAMKL_AMPK_PRKAA1_ST	O75385	ULK1	Q13131	PRKAA1	S556	P558S	558	Missense	proximal	2	no	75.749	75.206	EPSD	COSMIC	56.683	Down-regulation
CAMK_CAMKL_AMPK_PRKAA1_ST	O75385	ULK1	Q13131	PRKAA1	S556	L554Q	554	Missense	proximal	-2	no	75.749	77.398	EPSD	COSMIC	56.683	Up-regulation
CAMK_CAMKL_AMPK_PRKAA1_ST	O75385	ULK1	Q13131	PRKAA1	S638	P634L	634	Missense	distal	-4	no	63.868	63.616	PhosphoSitePlus	COSMIC;GDSC	56.683	Down-regulation
CAMK_CAMKL_AMPK_PRKAA1_ST	O75385	ULK1	Q13131	PRKAA1	S639	P634L	634	Missense	distal	-5	no	52.513	57.254	EPSD	COSMIC;GDSC	56.683	Gain
CAMK_CAMKL_AMPK_PRKAA1_ST	O75385	ULK1	Q13131	PRKAA1	T660	T660M	660	Missense	central	0	yes	65.978	0.000	EPSD	COSMIC	56.683	Loss
CAMK_CAMKL_AMPK_PRKAA1_ST	O75385	ULK1	Q13131	PRKAA1	T660	R659W	659	Missense	proximal	-1	no	65.978	66.065	EPSD	COSMIC	56.683	Up-regulation
CAMK_CAMKL_AMPK_PRKAA1_ST	O75385	ULK1	Q13131	PRKAA1	T660	T654M	654	Missense	distal	-6	no	65.978	64.672	EPSD	COSMIC	56.683	Down-regulation
CAMK_CAMKL_AMPK_PRKAA1_ST	O75385	ULK1	Q13131	PRKAA1	S665	T660M	660	Missense	distal	-5	no	52.291	57.786	EPSD	COSMIC	56.683	Gain
CAMK_CAMKL_AMPK_PRKAA1_ST	O75385	ULK1	Q13131	PRKAA1	S716	T717M	717	Missense	proximal	1	no	54.407	57.492	EPSD	COSMIC	56.683	Gain
CAMK_CAMKL_AMPK_PRKAA1_ST	O75385	ULK1	Q13131	PRKAA1	S763	Q767L	767	Missense	distal	4	no	49.107	58.672	EPSD	COSMIC	56.683	Gain
CAMK_CAMKL_AMPK_PRKAA1_ST	O75385	ULK1	Q13131	PRKAA1	S775	G768C	768	Missense	distal	-7	no	57.899	55.091	EPSD	COSMIC	56.683	Loss
CAMK_CAMKL_AMPK_PRKAA1_ST	O75385	ULK1	Q13131	PRKAA1	S775	S775L	775	Missense	central	0	yes	57.899	0.000	EPSD	COSMIC	56.683	Loss
CAMK_CAMKL_AMPK_PRKAA1_ST	O75385	ULK1	Q13131	PRKAA1	S775	P769L	769	Missense	distal	-6	no	57.899	57.860	EPSD	COSMIC	56.683	Down-regulation
CAMK_CAMKL_AMPK_PRKAA1_ST	O75385	ULK1	Q13131	PRKAA1	S775	T779I	779	Missense	distal	4	no	57.899	61.922	EPSD	COSMIC;CCLE	56.683	Up-regulation
CAMK_CAMKL_AMPK_PRKAA1_ST	O75385	ULK1	Q13131	PRKAA1	S1042	R1039W	1039	Missense	distal	-3	no	62.260	-30.740	EPSD	COSMIC	56.683	Loss
CAMK_CAMKL_AMPK_PRKAA1_ST	O75385	ULK1	Q13131	PRKAA1	S1042	L1045V	1045	Missense	distal	3	no	62.260	65.139	EPSD	COSMIC	56.683	Up-regulation
CAMK_CAMKL_AMPK_PRKAA1_ST	Q9BU19	ZNF692	Q13131	PRKAA1	S63	A70V	70	Missense	distal	7	no	60.157	57.739	EPSD	COSMIC	56.683	Down-regulation
CAMK_CAMKL_AMPK_PRKAA1_ST	Q9BU19	ZNF692	Q13131	PRKAA1	S63	L68I	68	Missense	distal	5	no	60.157	60.088	EPSD	COSMIC	56.683	Down-regulation
CAMK_CAMKL_AMPK_PRKAA1_ST	Q9BU19	ZNF692	Q13131	PRKAA1	T119	C114Y	114	Missense	distal	-5	no	65.670	63.164	EPSD	COSMIC	56.683	Down-regulation
CAMK_CAMKL_AMPK_PRKAA1_ST	Q9BU19	ZNF692	Q13131	PRKAA1	T119	E113K	113	Missense	distal	-6	no	65.670	66.040	EPSD	COSMIC	56.683	Up-regulation
CAMK_CAMKL_AMPK_PRKAA1_ST	Q9BU19	ZNF692	Q13131	PRKAA1	T119	G117D	117	Missense	proximal	-2	no	65.670	67.263	EPSD	COSMIC	56.683	Up-regulation
CAMK_CAMKL_AMPK_PRKAA1_ST	Q9BU19	ZNF692	Q13131	PRKAA1	T119	P124L	124	Missense	distal	5	no	65.670	65.663	EPSD	COSMIC	56.683	Down-regulation
CAMK_CAMKL_AMPK_PRKAA1_ST	Q9BU19	ZNF692	Q13131	PRKAA1	S153	E150K	150	Missense	distal	-3	no	60.384	64.225	EPSD	COSMIC	56.683	Up-regulation
CAMK_CAMKL_AMPK_PRKAA1_ST	Q9BU19	ZNF692	Q13131	PRKAA1	S153	L157F	157	Missense	distal	4	no	60.384	56.189	EPSD	COSMIC	56.683	Loss
CAMK_CAMKL_AMPK_PRKAA1_ST	Q9BU19	ZNF692	Q13131	PRKAA1	S153	S149T	149	Missense	distal	-4	no	60.384	59.129	EPSD	COSMIC	56.683	Down-regulation
CAMK_CAMKL_AMPK_PRKAA1_ST	Q9BU19	ZNF692	Q13131	PRKAA1	T412	P416S	416	Missense	distal	4	no	60.179	60.331	EPSD	COSMIC	56.683	Up-regulation
CAMK_CAMKL_AMPK_PRKAA1_ST	Q9BU19	ZNF692	Q13131	PRKAA1	T412	H411Q	411	Missense	proximal	-1	no	60.179	60.188	EPSD	COSMIC	56.683	Up-regulation
CAMK_CAMKL_AMPK_PRKAA1_ST	Q9BU19	ZNF692	Q13131	PRKAA1	S470	P472Q	472	Missense	proximal	2	no	67.376	66.450	PhosphoSitePlus	COSMIC;CCLE	56.683	Down-regulation
CAMK_CAMKL_AMPK_PRKAA1_ST	Q9BU19	ZNF692	Q13131	PRKAA1	S470	R467H	467	Missense	distal	-3	no	67.376	59.520	PhosphoSitePlus	COSMIC	56.683	Down-regulation
CAMK_CAMKL_AMPK_PRKAA1_ST	Q9BU19	ZNF692	Q13131	PRKAA1	S507	Q511K	511	Missense	distal	4	no	54.641	58.721	EPSD	COSMIC	56.683	Gain
CAMK_CAMKL_AMPK_PRKAA1_ST	O15350	TP73	Q13131	PRKAA1	T27	D30A	30	Missense	distal	3	no	69.200	64.480	EPSD	COSMIC	56.683	Down-regulation
CAMK_CAMKL_AMPK_PRKAA1_ST	O15350	TP73	Q13131	PRKAA1	T27	S26L	26	Missense	proximal	-1	no	69.200	69.225	EPSD	COSMIC	56.683	Up-regulation
CAMK_CAMKL_AMPK_PRKAA1_ST	O15350	TP73	Q13131	PRKAA1	S223	D227G	227	Missense	distal	4	no	58.421	58.063	EPSD	COSMIC	56.683	Down-regulation
CAMK_CAMKL_AMPK_PRKAA1_ST	O15350	TP73	Q13131	PRKAA1	S223	R216L	216	Missense	distal	-7	no	58.421	56.989	EPSD	COSMIC	56.683	Down-regulation
CAMK_CAMKL_AMPK_PRKAA1_ST	O15350	TP73	Q13131	PRKAA1	S223	G219D	219	Missense	distal	-4	no	58.421	61.935	EPSD	COSMIC	56.683	Up-regulation
CAMK_CAMKL_AMPK_PRKAA1_ST	O15350	TP73	Q13131	PRKAA1	S426	V427I	427	Missense	proximal	1	no	65.075	63.632	PhosphoSitePlus	COSMIC;CCLE	56.683	Down-regulation
CAMK_CAMKL_AMPK_PRKAA1_ST	O15350	TP73	Q13131	PRKAA1	S471	S468N	468	Missense	distal	-3	no	61.982	65.441	EPSD	COSMIC	56.683	Up-regulation
CAMK_CAMKL_AMPK_PRKAA1_ST	O15350	TP73	Q13131	PRKAA1	S471	S474P	474	Missense	distal	3	no	61.982	59.745	EPSD	COSMIC	56.683	Down-regulation
CAMK_CAMKL_AMPK_PRKAA1_ST	O15350	TP73	Q13131	PRKAA1	S471	G478R	478	Missense	distal	7	no	61.982	61.447	EPSD	COSMIC;CCLE	56.683	Down-regulation
CAMK_CAMKL_AMPK_PRKAA1_ST	O15350	TP73	Q13131	PRKAA1	S471	G464S	464	Missense	distal	-7	no	61.982	61.563	EPSD	COSMIC	56.683	Down-regulation
CAMK_CAMKL_AMPK_PRKAA1_ST	Q05469	LIPE	Q13131	PRKAA1	S200	Q198H	198	Missense	proximal	-2	no	63.427	60.243	EPSD	COSMIC	56.683	Down-regulation
CAMK_CAMKL_AMPK_PRKAA1_ST	Q05469	LIPE	Q13131	PRKAA1	T202	K209E	209	Missense	distal	7	no	56.926	57.622	EPSD	COSMIC	56.683	Up-regulation
CAMK_CAMKL_AMPK_PRKAA1_ST	Q05469	LIPE	Q13131	PRKAA1	T202	Q198H	198	Missense	distal	-4	no	56.926	55.008	EPSD	COSMIC	56.683	Loss
CAMK_CAMKL_AMPK_PRKAA1_ST	Q05469	LIPE	Q13131	PRKAA1	S607	V603I	603	Missense	distal	-4	no	63.227	61.822	EPSD	COSMIC	56.683	Down-regulation
CAMK_CAMKL_AMPK_PRKAA1_ST	Q05469	LIPE	Q13131	PRKAA1	S621	N626K	626	Missense	distal	5	no	56.754	56.767	EPSD	COSMIC	56.683	Up-regulation
CAMK_CAMKL_AMPK_PRKAA1_ST	Q05469	LIPE	Q13131	PRKAA1	S621	L622P	622	Missense	proximal	1	no	56.754	57.047	EPSD	COSMIC	56.683	Up-regulation
CAMK_CAMKL_AMPK_PRKAA1_ST	Q05469	LIPE	Q13131	PRKAA1	S621	G627C	627	Missense	distal	6	no	56.754	57.206	EPSD	COSMIC	56.683	Up-regulation
CAMK_CAMKL_AMPK_PRKAA1_ST	Q05469	LIPE	Q13131	PRKAA1	T813	R818Q	818	Missense	distal	5	no	63.032	63.077	EPSD	COSMIC;GDSC	56.683	Up-regulation
CAMK_CAMKL_AMPK_PRKAA1_ST	Q05469	LIPE	Q13131	PRKAA1	T813	L815P	815	Missense	proximal	2	no	63.032	63.631	EPSD	COSMIC	56.683	Up-regulation
CAMK_CAMKL_AMPK_PRKAA1_ST	Q05469	LIPE	Q13131	PRKAA1	T875	T868M	868	Missense	distal	-7	no	65.124	67.404	EPSD	COSMIC	56.683	Up-regulation
CAMK_CAMKL_AMPK_PRKAA1_ST	Q05469	LIPE	Q13131	PRKAA1	S904	A898V	898	Missense	distal	-6	no	57.314	55.462	EPSD	COSMIC	56.683	Loss
CAMK_CAMKL_AMPK_PRKAA1_ST	Q05469	LIPE	Q13131	PRKAA1	S904	A898S	898	Missense	distal	-6	no	57.314	56.644	EPSD	COSMIC	56.683	Loss
CAMK_CAMKL_AMPK_PRKAA1_ST	Q05469	LIPE	Q13131	PRKAA1	T1052	P1054R	1054	Missense	proximal	2	no	61.735	61.285	EPSD	COSMIC	56.683	Down-regulation
CAMK_CAMKL_AMPK_PRKAA1_ST	Q05469	LIPE	Q13131	PRKAA1	T1052	R1048H	1048	Missense	distal	-4	no	61.735	58.348	EPSD	COSMIC	56.683	Down-regulation
CAMK_CAMKL_AMPK_PRKAA1_ST	Q6N021	TET2	Q13131	PRKAA1	S99	R96C	96	Missense	distal	-3	no	59.609	45.462	PhosphoSitePlus	COSMIC	56.683	Loss
CAMK_CAMKL_AMPK_PRKAA1_ST	Q6N021	TET2	Q13131	PRKAA1	S99	T97I	97	Missense	proximal	-2	no	59.609	60.415	PhosphoSitePlus	COSMIC	56.683	Up-regulation
CAMK_CAMKL_AMPK_PRKAA1_ST	Q6N021	TET2	Q13131	PRKAA1	S99	L103V	103	Missense	distal	4	no	59.609	55.112	PhosphoSitePlus	COSMIC	56.683	Loss
CAMK_CAMKL_AMPK_PRKAA1_ST	Q6N021	TET2	Q13131	PRKAA1	S99	P101T	101	Missense	proximal	2	no	59.609	59.312	PhosphoSitePlus	COSMIC	56.683	Down-regulation
CAMK_CAMKL_AMPK_PRKAA1_ST	Q6N021	TET2	Q13131	PRKAA1	S315	Q317K	317	Missense	proximal	2	no	58.201	58.793	EPSD	COSMIC;GDSC	56.683	Up-regulation
CAMK_CAMKL_AMPK_PRKAA1_ST	Q6N021	TET2	Q13131	PRKAA1	S315	F316L	316	Missense	proximal	1	no	58.201	52.735	EPSD	COSMIC	56.683	Loss
CAMK_CAMKL_AMPK_PRKAA1_ST	Q6N021	TET2	Q13131	PRKAA1	S315	N312S	312	Missense	distal	-3	no	58.201	54.742	EPSD	COSMIC	56.683	Loss
CAMK_CAMKL_AMPK_PRKAA1_ST	Q6N021	TET2	Q13131	PRKAA1	S327	I331L	331	Missense	distal	4	no	57.664	60.740	EPSD	COSMIC	56.683	Up-regulation
CAMK_CAMKL_AMPK_PRKAA1_ST	Q6N021	TET2	Q13131	PRKAA1	S327	F329L	329	Missense	proximal	2	no	57.664	57.900	EPSD	COSMIC	56.683	Up-regulation
CAMK_CAMKL_AMPK_PRKAA1_ST	Q6N021	TET2	Q13131	PRKAA1	T467	S462R	462	Missense	distal	-5	no	54.197	57.202	EPSD	COSMIC	56.683	Gain
CAMK_CAMKL_AMPK_PRKAA1_ST	Q6N021	TET2	Q13131	PRKAA1	S585	S585L	585	Missense	central	0	yes	62.930	0.000	EPSD	COSMIC	56.683	Loss
CAMK_CAMKL_AMPK_PRKAA1_ST	Q6N021	TET2	Q13131	PRKAA1	S585	L579Q	579	Missense	distal	-6	no	62.930	63.449	EPSD	COSMIC	56.683	Up-regulation
CAMK_CAMKL_AMPK_PRKAA1_ST	Q6N021	TET2	Q13131	PRKAA1	S585	P587L	587	Missense	proximal	2	no	62.930	62.331	EPSD	COSMIC	56.683	Down-regulation
CAMK_CAMKL_AMPK_PRKAA1_ST	Q6N021	TET2	Q13131	PRKAA1	S585	P587S	587	Missense	proximal	2	no	62.930	62.387	EPSD	COSMIC	56.683	Down-regulation
CAMK_CAMKL_AMPK_PRKAA1_ST	Q6N021	TET2	Q13131	PRKAA1	S585	N582S	582	Missense	distal	-3	no	62.930	59.471	EPSD	COSMIC	56.683	Down-regulation
CAMK_CAMKL_AMPK_PRKAA1_ST	Q6N021	TET2	Q13131	PRKAA1	S817	T822P	822	Missense	distal	5	no	60.010	60.003	EPSD	COSMIC	56.683	Down-regulation
CAMK_CAMKL_AMPK_PRKAA1_ST	Q6N021	TET2	Q13131	PRKAA1	S817	Q810R	810	Missense	distal	-7	no	60.010	59.833	EPSD	COSMIC	56.683	Down-regulation
CAMK_CAMKL_AMPK_PRKAA1_ST	Q6N021	TET2	Q13131	PRKAA1	S817	R815I	815	Missense	proximal	-2	no	60.010	59.373	EPSD	COSMIC	56.683	Down-regulation
CAMK_CAMKL_AMPK_PRKAA1_ST	Q6N021	TET2	Q13131	PRKAA1	S1076	A1072T	1072	Missense	distal	-4	no	60.091	59.236	EPSD	COSMIC	56.683	Down-regulation
CAMK_CAMKL_AMPK_PRKAA1_ST	Q6N021	TET2	Q13131	PRKAA1	S1076	A1071G	1071	Missense	distal	-5	no	60.091	59.577	EPSD	COSMIC	56.683	Down-regulation
CAMK_CAMKL_AMPK_PRKAA1_ST	Q6N021	TET2	Q13131	PRKAA1	S1076	T1078P	1078	Missense	proximal	2	no	60.091	60.389	EPSD	COSMIC	56.683	Up-regulation
CAMK_CAMKL_AMPK_PRKAA1_ST	Q6N021	TET2	Q13131	PRKAA1	S1076	A1072P	1072	Missense	distal	-4	no	60.091	59.248	EPSD	COSMIC	56.683	Down-regulation
CAMK_CAMKL_AMPK_PRKAA1_ST	Q6N021	TET2	Q13131	PRKAA1	S1076	T1069P	1069	Missense	distal	-7	no	60.091	59.677	EPSD	COSMIC	56.683	Down-regulation
CAMK_CAMKL_AMPK_PRKAA1_ST	Q6N021	TET2	Q13131	PRKAA1	T1126	D1129N	1129	Missense	distal	3	no	55.505	56.759	EPSD	COSMIC	56.683	Gain
CAMK_CAMKL_AMPK_PRKAA1_ST	Q6N021	TET2	Q13131	PRKAA1	T1331	L1332P	1332	Missense	proximal	1	no	60.237	60.530	EPSD	COSMIC	56.683	Up-regulation
CAMK_CAMKL_AMPK_PRKAA1_ST	Q6N021	TET2	Q13131	PRKAA1	T1331	L1329Q	1329	Missense	proximal	-2	no	60.237	61.885	EPSD	COSMIC	56.683	Up-regulation
CAMK_CAMKL_AMPK_PRKAA1_ST	Q6N021	TET2	Q13131	PRKAA1	T1331	L1329P	1329	Missense	proximal	-2	no	60.237	63.211	EPSD	COSMIC	56.683	Up-regulation
CAMK_CAMKL_AMPK_PRKAA1_ST	Q6N021	TET2	Q13131	PRKAA1	T1331	L1329R	1329	Missense	proximal	-2	no	60.237	61.423	EPSD	COSMIC	56.683	Up-regulation
CAMK_CAMKL_AMPK_PRKAA1_ST	Q6N021	TET2	Q13131	PRKAA1	T1331	S1330F	1330	Missense	proximal	-1	no	60.237	60.190	EPSD	COSMIC	56.683	Down-regulation
CAMK_CAMKL_AMPK_PRKAA1_ST	Q6N021	TET2	Q13131	PRKAA1	T1331	P1335Q	1335	Missense	distal	4	no	60.237	57.411	EPSD	COSMIC	56.683	Down-regulation
CAMK_CAMKL_AMPK_PRKAA1_ST	Q6N021	TET2	Q13131	PRKAA1	T1331	K1338T	1338	Missense	distal	7	no	60.237	61.463	EPSD	COSMIC	56.683	Up-regulation
CAMK_CAMKL_AMPK_PRKAA1_ST	Q6N021	TET2	Q13131	PRKAA1	T1331	M1333K	1333	Missense	proximal	2	no	60.237	60.353	EPSD	COSMIC	56.683	Up-regulation
CAMK_CAMKL_AMPK_PRKAA1_ST	Q6N021	TET2	Q13131	PRKAA1	T1331	Q1327P	1327	Missense	distal	-4	no	60.237	59.398	EPSD	COSMIC	56.683	Down-regulation
CAMK_CAMKL_AMPK_PRKAA1_ST	Q6N021	TET2	Q13131	PRKAA1	T1331	L1329M	1329	Missense	proximal	-2	no	60.237	60.249	EPSD	COSMIC;GDSC;CCLE	56.683	Up-regulation
CAMK_CAMKL_AMPK_PRKAA1_ST	Q6N021	TET2	Q13131	PRKAA1	T1331	L1326S	1326	Missense	distal	-5	no	60.237	56.054	EPSD	COSMIC	56.683	Loss
CAMK_CAMKL_AMPK_PRKAA1_ST	Q6N021	TET2	Q13131	PRKAA1	T1331	L1332F	1332	Missense	proximal	1	no	60.237	65.702	EPSD	COSMIC	56.683	Up-regulation
CAMK_CAMKL_AMPK_PRKAA1_ST	Q6N021	TET2	Q13131	PRKAA1	T1331	K1338E	1338	Missense	distal	7	no	60.237	60.933	EPSD	COSMIC	56.683	Up-regulation
CAMK_CAMKL_AMPK_PRKAA1_ST	Q6N021	TET2	Q13131	PRKAA1	T1331	S1324N	1324	Missense	distal	-7	no	60.237	59.146	EPSD	COSMIC	56.683	Down-regulation
CAMK_CAMKL_AMPK_PRKAA1_ST	Q6N021	TET2	Q13131	PRKAA1	T1331	S1324R	1324	Missense	distal	-7	no	60.237	59.241	EPSD	COSMIC	56.683	Down-regulation
CAMK_CAMKL_AMPK_PRKAA1_ST	Q6N021	TET2	Q13131	PRKAA1	S1449	F1450S	1450	Missense	proximal	1	no	64.294	59.754	EPSD	COSMIC	56.683	Down-regulation
CAMK_CAMKL_AMPK_PRKAA1_ST	Q6N021	TET2	Q13131	PRKAA1	S1449	Q1445R	1445	Missense	distal	-4	no	64.294	65.762	EPSD	COSMIC	56.683	Up-regulation
CAMK_CAMKL_AMPK_PRKAA1_ST	Q6N021	TET2	Q13131	PRKAA1	S1449	Q1445K	1445	Missense	distal	-4	no	64.294	62.582	EPSD	COSMIC	56.683	Down-regulation
CAMK_CAMKL_AMPK_PRKAA1_ST	Q6N021	TET2	Q13131	PRKAA1	S1449	R1452Q	1452	Missense	distal	3	no	64.294	65.687	EPSD	COSMIC;GDSC	56.683	Up-regulation
CAMK_CAMKL_AMPK_PRKAA1_ST	Q6N021	TET2	Q13131	PRKAA1	S1449	V1454G	1454	Missense	distal	5	no	64.294	64.304	EPSD	COSMIC	56.683	Up-regulation
CAMK_CAMKL_AMPK_PRKAA1_ST	Q6N021	TET2	Q13131	PRKAA1	S1970	T1963I	1963	Missense	distal	-7	no	60.402	59.904	EPSD	COSMIC	56.683	Down-regulation
CAMK_CAMKL_AMPK_PRKAA1_ST	Q6N021	TET2	Q13131	PRKAA1	S1970	R1966H	1966	Missense	distal	-4	no	60.402	57.016	EPSD	COSMIC	56.683	Down-regulation
CAMK_CAMKL_AMPK_PRKAA1_ST	Q6N021	TET2	Q13131	PRKAA1	S1970	R1966C	1966	Missense	distal	-4	no	60.402	64.713	EPSD	COSMIC	56.683	Up-regulation
CAMK_CAMKL_AMPK_PRKAA1_ST	Q6N021	TET2	Q13131	PRKAA1	S1970	Y1964H	1964	Missense	distal	-6	no	60.402	61.838	EPSD	COSMIC	56.683	Up-regulation
CAMK_CAMKL_AMPK_PRKAA1_ST	Q6N021	TET2	Q13131	PRKAA1	S1970	S1970C	1970	Missense	central	0	yes	60.402	0.000	EPSD	COSMIC	56.683	Loss
CAMK_CAMKL_AMPK_PRKAA1_ST	Q6N021	TET2	Q13131	PRKAA1	S1970	S1970P	1970	Missense	central	0	yes	60.402	0.000	EPSD	COSMIC	56.683	Loss
CAMK_CAMKL_AMPK_PRKAA1_ST	Q6N021	TET2	Q13131	PRKAA1	S1970	L1971V	1971	Missense	proximal	1	no	60.402	61.192	EPSD	COSMIC	56.683	Up-regulation
CAMK_CAMKL_AMPK_PRKAA1_ST	Q15910	EZH2	Q13131	PRKAA1	S212	R207W	207	Missense	distal	-5	no	59.827	54.634	EPSD	COSMIC	56.683	Loss
CAMK_CAMKL_AMPK_PRKAA1_ST	Q15910	EZH2	Q13131	PRKAA1	S212	R213H	213	Missense	proximal	1	no	59.827	62.825	EPSD	COSMIC	56.683	Up-regulation
CAMK_CAMKL_AMPK_PRKAA1_ST	Q15910	EZH2	Q13131	PRKAA1	S212	R213C	213	Missense	proximal	1	no	59.827	60.151	EPSD	COSMIC	56.683	Up-regulation
CAMK_CAMKL_AMPK_PRKAA1_ST	Q15910	EZH2	Q13131	PRKAA1	S212	K210E	210	Missense	proximal	-2	no	59.827	58.552	EPSD	COSMIC	56.683	Down-regulation
CAMK_CAMKL_AMPK_PRKAA1_ST	Q15910	EZH2	Q13131	PRKAA1	S212	P219S	219	Missense	distal	7	no	59.827	60.325	EPSD	COSMIC;GDSC;CCLE	56.683	Up-regulation
CAMK_CAMKL_AMPK_PRKAA1_ST	Q15910	EZH2	Q13131	PRKAA1	S212	P215S	215	Missense	distal	3	no	59.827	62.064	EPSD	COSMIC;GDSC	56.683	Up-regulation
CAMK_CAMKL_AMPK_PRKAA1_ST	Q15910	EZH2	Q13131	PRKAA1	S212	R216W	216	Missense	distal	4	no	59.827	63.078	EPSD	COSMIC	56.683	Up-regulation
CAMK_CAMKL_AMPK_PRKAA1_ST	Q15910	EZH2	Q13131	PRKAA1	S212	H206Q	206	Missense	distal	-6	no	59.827	61.718	EPSD	COSMIC	56.683	Up-regulation
CAMK_CAMKL_AMPK_PRKAA1_ST	Q15910	EZH2	Q13131	PRKAA1	S220	I223F	223	Missense	distal	3	no	55.996	57.165	EPSD	COSMIC	56.683	Gain
CAMK_CAMKL_AMPK_PRKAA1_ST	Q15910	EZH2	Q13131	PRKAA1	S277	S271C	271	Missense	distal	-6	no	61.801	58.196	EPSD	COSMIC	56.683	Down-regulation
CAMK_CAMKL_AMPK_PRKAA1_ST	Q15910	EZH2	Q13131	PRKAA1	S277	H279Q	279	Missense	proximal	2	no	61.801	61.029	EPSD	COSMIC	56.683	Down-regulation
CAMK_CAMKL_AMPK_PRKAA1_ST	Q15910	EZH2	Q13131	PRKAA1	S277	H282Y	282	Missense	distal	5	no	61.801	62.047	EPSD	COSMIC	56.683	Up-regulation
CAMK_CAMKL_AMPK_PRKAA1_ST	Q15910	EZH2	Q13131	PRKAA1	S277	T283M	283	Missense	distal	6	no	61.801	61.975	EPSD	COSMIC	56.683	Up-regulation
CAMK_CAMKL_AMPK_PRKAA1_ST	Q15910	EZH2	Q13131	PRKAA1	S277	H279Y	279	Missense	proximal	2	no	61.801	60.945	EPSD	COSMIC;GDSC;CCLE	56.683	Down-regulation
CAMK_CAMKL_AMPK_PRKAA1_ST	Q15910	EZH2	Q13131	PRKAA1	S277	S280C	280	Missense	distal	3	no	61.801	59.970	EPSD	COSMIC	56.683	Down-regulation
CAMK_CAMKL_AMPK_PRKAA1_ST	Q15910	EZH2	Q13131	PRKAA1	T311	R308Q	308	Missense	distal	-3	no	60.061	52.117	PhosphoSitePlus	COSMIC	56.683	Loss
CAMK_CAMKL_AMPK_PRKAA1_ST	Q15910	EZH2	Q13131	PRKAA1	T311	N317S	317	Missense	distal	6	no	60.061	60.179	PhosphoSitePlus	COSMIC	56.683	Up-regulation
CAMK_CAMKL_AMPK_PRKAA1_ST	Q15910	EZH2	Q13131	PRKAA1	T311	L315V	315	Missense	distal	4	no	60.061	55.564	PhosphoSitePlus	COSMIC	56.683	Loss
CAMK_CAMKL_AMPK_PRKAA1_ST	Q15910	EZH2	Q13131	PRKAA1	T311	N304S	304	Missense	distal	-7	no	60.061	61.152	PhosphoSitePlus	COSMIC	56.683	Up-regulation
CAMK_CAMKL_AMPK_PRKAA1_ST	Q15910	EZH2	Q13131	PRKAA1	T311	R308L	308	Missense	distal	-3	no	60.061	50.095	PhosphoSitePlus	COSMIC	56.683	Loss
CAMK_CAMKL_AMPK_PRKAA1_ST	Q15910	EZH2	Q13131	PRKAA1	T311	R308W	308	Missense	distal	-3	no	60.061	-32.939	PhosphoSitePlus	COSMIC	56.683	Loss
CAMK_CAMKL_AMPK_PRKAA1_ST	Q15910	EZH2	Q13131	PRKAA1	T311	L315P	315	Missense	distal	4	no	60.061	53.321	PhosphoSitePlus	COSMIC	56.683	Loss
CAMK_CAMKL_AMPK_PRKAA1_ST	Q15910	EZH2	Q13131	PRKAA1	T311	E312K	312	Missense	proximal	1	no	60.061	60.991	PhosphoSitePlus	COSMIC	56.683	Up-regulation
CAMK_CAMKL_AMPK_PRKAA1_ST	Q15910	EZH2	Q13131	PRKAA1	T311	N310S	310	Missense	proximal	-1	no	60.061	60.101	PhosphoSitePlus	COSMIC	56.683	Up-regulation
CAMK_CAMKL_AMPK_PRKAA1_ST	Q15910	EZH2	Q13131	PRKAA1	S362	S366L	366	Missense	distal	4	no	50.704	57.292	EPSD	COSMIC	56.683	Gain
CAMK_CAMKL_AMPK_PRKAA1_ST	Q15910	EZH2	Q13131	PRKAA1	S412	E409K	409	Missense	distal	-3	no	54.435	58.276	EPSD	COSMIC	56.683	Gain
CAMK_CAMKL_AMPK_PRKAA1_ST	Q15910	EZH2	Q13131	PRKAA1	S647	G643E	643	Missense	distal	-4	no	53.398	56.951	EPSD	COSMIC;CCLE	56.683	Gain
CAMK_CAMKL_AMPK_PRKAA1_ST	Q15910	EZH2	Q13131	PRKAA1	S647	G643R	643	Missense	distal	-4	no	53.398	57.005	EPSD	COSMIC	56.683	Gain
CAMK_CAMKL_AMPK_PRKAA1_ST	Q15910	EZH2	Q13131	PRKAA1	S647	Y641D	641	Missense	distal	-6	no	53.398	58.282	EPSD	COSMIC	56.683	Gain
CAMK_CAMKL_AMPK_PRKAA1_ST	Q15910	EZH2	Q13131	PRKAA1	T718	E721Q	721	Missense	distal	3	no	55.943	57.655	EPSD	COSMIC	56.683	Gain
CAMK_CAMKL_AMPK_PRKAA1_ST	Q15910	EZH2	Q13131	PRKAA1	T718	A715V	715	Missense	distal	-3	no	55.943	58.386	EPSD	COSMIC	56.683	Gain
CAMK_CAMKL_AMPK_PRKAA1_ST	Q15910	EZH2	Q13131	PRKAA1	T718	D725Y	725	Missense	distal	7	no	55.943	57.411	EPSD	COSMIC	56.683	Gain
CAMK_CAMKL_AMPK_PRKAA1_ST	Q15910	EZH2	Q13131	PRKAA1	T718	E721V	721	Missense	distal	3	no	55.943	57.809	EPSD	COSMIC	56.683	Gain
CAMK_CAMKL_AMPK_PRKAA1_ST	P36956	SREBF1	Q13131	PRKAA1	S396	S396F	396	Missense	central	0	yes	60.521	0.000	EPSD	COSMIC	56.683	Loss
CAMK_CAMKL_AMPK_PRKAA1_ST	P36956	SREBF1	Q13131	PRKAA1	S396	K393R	393	Missense	distal	-3	no	60.521	65.162	EPSD	COSMIC	56.683	Up-regulation
CAMK_CAMKL_AMPK_PRKAA1_ST	P36956	SREBF1	Q13131	PRKAA1	S396	T389I	389	Missense	distal	-7	no	60.521	60.022	EPSD	COSMIC	56.683	Down-regulation
CAMK_CAMKL_AMPK_PRKAA1_ST	P36956	SREBF1	Q13131	PRKAA1	S396	K395N	395	Missense	proximal	-1	no	60.521	60.587	EPSD	COSMIC	56.683	Up-regulation
CAMK_CAMKL_AMPK_PRKAA1_ST	P36956	SREBF1	Q13131	PRKAA1	S434	P440H	440	Missense	distal	6	no	57.896	57.910	EPSD	COSMIC	56.683	Up-regulation
CAMK_CAMKL_AMPK_PRKAA1_ST	P36956	SREBF1	Q13131	PRKAA1	S439	L443F	443	Missense	distal	4	no	62.357	58.162	EPSD	COSMIC	56.683	Down-regulation
CAMK_CAMKL_AMPK_PRKAA1_ST	P36956	SREBF1	Q13131	PRKAA1	S439	P440H	440	Missense	proximal	1	no	62.357	65.001	EPSD	COSMIC	56.683	Up-regulation
CAMK_CAMKL_AMPK_PRKAA1_ST	P36956	SREBF1	Q13131	PRKAA1	S1019	R1012C	1012	Missense	distal	-7	no	60.775	59.382	EPSD	COSMIC;CCLE	56.683	Down-regulation
CAMK_CAMKL_AMPK_PRKAA1_ST	Q09472	EP300	Q13131	PRKAA1	S28	G30V	30	Missense	proximal	2	no	56.080	57.535	EPSD	COSMIC;CCLE	56.683	Gain
CAMK_CAMKL_AMPK_PRKAA1_ST	Q09472	EP300	Q13131	PRKAA1	S28	G30D	30	Missense	proximal	2	no	56.080	57.232	EPSD	COSMIC	56.683	Gain
CAMK_CAMKL_AMPK_PRKAA1_ST	Q09472	EP300	Q13131	PRKAA1	S89	M95V	95	Missense	distal	6	no	74.231	74.012	PhosphoSitePlus	COSMIC	56.683	Down-regulation
CAMK_CAMKL_AMPK_PRKAA1_ST	Q09472	EP300	Q13131	PRKAA1	S89	S87Y	87	Missense	proximal	-2	no	74.231	72.669	PhosphoSitePlus	COSMIC	56.683	Down-regulation
CAMK_CAMKL_AMPK_PRKAA1_ST	Q09472	EP300	Q13131	PRKAA1	T845	P842S	842	Missense	distal	-3	no	62.942	62.407	EPSD	COSMIC;CCLE	56.683	Down-regulation
CAMK_CAMKL_AMPK_PRKAA1_ST	Q09472	EP300	Q13131	PRKAA1	T845	T839I	839	Missense	distal	-6	no	62.942	59.803	EPSD	COSMIC	56.683	Down-regulation
CAMK_CAMKL_AMPK_PRKAA1_ST	Q09472	EP300	Q13131	PRKAA1	T845	P846S	846	Missense	proximal	1	no	62.942	63.575	EPSD	COSMIC	56.683	Up-regulation
CAMK_CAMKL_AMPK_PRKAA1_ST	Q09472	EP300	Q13131	PRKAA1	T845	P847S	847	Missense	proximal	2	no	62.942	62.399	EPSD	COSMIC	56.683	Down-regulation
CAMK_CAMKL_AMPK_PRKAA1_ST	Q09472	EP300	Q13131	PRKAA1	T845	I849T	849	Missense	distal	4	no	62.942	58.920	EPSD	COSMIC	56.683	Down-regulation
CAMK_CAMKL_AMPK_PRKAA1_ST	Q09472	EP300	Q13131	PRKAA1	T845	P842L	842	Missense	distal	-3	no	62.942	61.835	EPSD	COSMIC	56.683	Down-regulation
CAMK_CAMKL_AMPK_PRKAA1_ST	Q09472	EP300	Q13131	PRKAA1	T845	R838S	838	Missense	distal	-7	no	62.942	63.938	EPSD	COSMIC	56.683	Up-regulation
CAMK_CAMKL_AMPK_PRKAA1_ST	Q09472	EP300	Q13131	PRKAA1	T857	I859S	859	Missense	proximal	2	no	57.328	57.940	EPSD	COSMIC	56.683	Up-regulation
CAMK_CAMKL_AMPK_PRKAA1_ST	Q09472	EP300	Q13131	PRKAA1	T857	P864S	864	Missense	distal	7	no	57.328	57.826	EPSD	COSMIC	56.683	Up-regulation
CAMK_CAMKL_AMPK_PRKAA1_ST	Q09472	EP300	Q13131	PRKAA1	S1016	I1023V	1023	Missense	distal	7	no	61.915	60.717	EPSD	COSMIC	56.683	Down-regulation
CAMK_CAMKL_AMPK_PRKAA1_ST	Q09472	EP300	Q13131	PRKAA1	S1016	T1010I	1010	Missense	distal	-6	no	61.915	58.775	EPSD	COSMIC	56.683	Down-regulation
CAMK_CAMKL_AMPK_PRKAA1_ST	Q09472	EP300	Q13131	PRKAA1	S1016	E1013Q	1013	Missense	distal	-3	no	61.915	62.452	EPSD	COSMIC	56.683	Up-regulation
CAMK_CAMKL_AMPK_PRKAA1_ST	Q09472	EP300	Q13131	PRKAA1	S1016	T1010A	1010	Missense	distal	-6	no	61.915	62.118	EPSD	COSMIC	56.683	Up-regulation
CAMK_CAMKL_AMPK_PRKAA1_ST	Q09472	EP300	Q13131	PRKAA1	S1016	E1013G	1013	Missense	distal	-3	no	61.915	61.361	EPSD	COSMIC	56.683	Down-regulation
CAMK_CAMKL_AMPK_PRKAA1_ST	Q09472	EP300	Q13131	PRKAA1	S1016	E1011K	1011	Missense	distal	-5	no	61.915	59.267	EPSD	COSMIC	56.683	Down-regulation
CAMK_CAMKL_AMPK_PRKAA1_ST	Q09472	EP300	Q13131	PRKAA1	S1016	E1014D	1014	Missense	proximal	-2	no	61.915	61.339	EPSD	COSMIC	56.683	Down-regulation
CAMK_CAMKL_AMPK_PRKAA1_ST	Q09472	EP300	Q13131	PRKAA1	T1190	D1188N	1188	Missense	proximal	-2	no	62.566	63.618	EPSD	COSMIC	56.683	Up-regulation
CAMK_CAMKL_AMPK_PRKAA1_ST	Q09472	EP300	Q13131	PRKAA1	T1190	R1197W	1197	Missense	distal	7	no	62.566	62.791	EPSD	COSMIC	56.683	Up-regulation
CAMK_CAMKL_AMPK_PRKAA1_ST	Q09472	EP300	Q13131	PRKAA1	T1190	Q1195H	1195	Missense	distal	5	no	62.566	62.328	EPSD	COSMIC	56.683	Down-regulation
CAMK_CAMKL_AMPK_PRKAA1_ST	Q09472	EP300	Q13131	PRKAA1	T1190	C1183Y	1183	Missense	distal	-7	no	62.566	62.816	EPSD	COSMIC	56.683	Up-regulation
CAMK_CAMKL_AMPK_PRKAA1_ST	Q09472	EP300	Q13131	PRKAA1	T1296	T1300I	1300	Missense	distal	4	no	53.591	57.614	EPSD	COSMIC	56.683	Gain
CAMK_CAMKL_AMPK_PRKAA1_ST	Q09472	EP300	Q13131	PRKAA1	S1534	S1534G	1534	Missense	central	0	yes	58.344	0.000	EPSD	COSMIC	56.683	Loss
CAMK_CAMKL_AMPK_PRKAA1_ST	Q09472	EP300	Q13131	PRKAA1	S1534	E1536K	1536	Missense	proximal	2	no	58.344	57.950	EPSD	COSMIC	56.683	Down-regulation
CAMK_CAMKL_AMPK_PRKAA1_ST	Q09472	EP300	Q13131	PRKAA1	S1534	E1536G	1536	Missense	proximal	2	no	58.344	57.231	EPSD	COSMIC	56.683	Down-regulation
CAMK_CAMKL_AMPK_PRKAA1_ST	Q09472	EP300	Q13131	PRKAA1	S1534	T1541I	1541	Missense	distal	7	no	58.344	57.498	EPSD	COSMIC	56.683	Down-regulation
CAMK_CAMKL_AMPK_PRKAA1_ST	Q09472	EP300	Q13131	PRKAA1	S1834	G1839D	1839	Missense	distal	5	no	58.929	59.080	EPSD	COSMIC	56.683	Up-regulation
CAMK_CAMKL_AMPK_PRKAA1_ST	Q09472	EP300	Q13131	PRKAA1	S1834	T1838N	1838	Missense	distal	4	no	58.929	57.970	EPSD	COSMIC	56.683	Down-regulation
CAMK_CAMKL_AMPK_PRKAA1_ST	Q09472	EP300	Q13131	PRKAA1	S1834	G1839S	1839	Missense	distal	5	no	58.929	58.973	EPSD	COSMIC	56.683	Up-regulation
CAMK_CAMKL_AMPK_PRKAA1_ST	Q09472	EP300	Q13131	PRKAA1	S1834	R1837W	1837	Missense	distal	3	no	58.929	60.987	EPSD	COSMIC	56.683	Up-regulation
CAMK_CAMKL_AMPK_PRKAA1_ST	Q09472	EP300	Q13131	PRKAA1	S1849	P1855S	1855	Missense	distal	6	no	59.898	59.913	EPSD	COSMIC	56.683	Up-regulation
CAMK_CAMKL_AMPK_PRKAA1_ST	Q09472	EP300	Q13131	PRKAA1	S1849	G1842E	1842	Missense	distal	-7	no	59.898	58.692	EPSD	COSMIC	56.683	Down-regulation
CAMK_CAMKL_AMPK_PRKAA1_ST	Q09472	EP300	Q13131	PRKAA1	S1849	P1848S	1848	Missense	proximal	-1	no	59.898	59.943	EPSD	COSMIC	56.683	Up-regulation
CAMK_CAMKL_AMPK_PRKAA1_ST	Q09472	EP300	Q13131	PRKAA1	S1897	S1897F	1897	Missense	central	0	yes	62.414	0.000	EPSD	COSMIC	56.683	Loss
CAMK_CAMKL_AMPK_PRKAA1_ST	Q09472	EP300	Q13131	PRKAA1	S1897	G1899D	1899	Missense	proximal	2	no	62.414	63.566	EPSD	COSMIC	56.683	Up-regulation
CAMK_CAMKL_AMPK_PRKAA1_ST	Q09472	EP300	Q13131	PRKAA1	S2325	H2324T	2324	Missense	proximal	-1	no	59.282	59.238	EPSD	COSMIC	56.683	Down-regulation
CAMK_CAMKL_AMPK_PRKAA1_ST	Q09472	EP300	Q13131	PRKAA1	S2325	H2324Y	2324	Missense	proximal	-1	no	59.282	59.409	EPSD	COSMIC	56.683	Up-regulation
CAMK_CAMKL_AMPK_PRKAA1_ST	Q86TI0	TBC1D1	Q13131	PRKAA1	S237	R230M	230	Missense	distal	-7	no	63.626	65.049	EPSD;PhosphoSitePlus	COSMIC;GDSC;CCLE	56.683	Up-regulation
CAMK_CAMKL_AMPK_PRKAA1_ST	Q86TI0	TBC1D1	Q13131	PRKAA1	S237	S243L	243	Missense	distal	6	no	63.626	63.760	EPSD;PhosphoSitePlus	COSMIC	56.683	Up-regulation
CAMK_CAMKL_AMPK_PRKAA1_ST	Q86TI0	TBC1D1	Q13131	PRKAA1	S237	R230K	230	Missense	distal	-7	no	63.626	65.230	EPSD;PhosphoSitePlus	COSMIC	56.683	Up-regulation
CAMK_CAMKL_AMPK_PRKAA1_ST	Q86TI0	TBC1D1	Q13131	PRKAA1	S237	S237F	237	Missense	central	0	yes	63.626	0.000	EPSD;PhosphoSitePlus	COSMIC;GDSC;CCLE	56.683	Loss
CAMK_CAMKL_AMPK_PRKAA1_ST	Q86TI0	TBC1D1	Q13131	PRKAA1	S513	S507F	507	Missense	distal	-6	no	57.727	57.830	EPSD	COSMIC	56.683	Up-regulation
CAMK_CAMKL_AMPK_PRKAA1_ST	Q9H3M7	TXNIP	Q13131	PRKAA1	S304	S307Y	307	Missense	distal	3	no	62.361	63.281	EPSD	COSMIC	56.683	Up-regulation
CAMK_CAMKL_AMPK_PRKAA1_ST	Q9H3M7	TXNIP	Q13131	PRKAA1	S308	S307Y	307	Missense	proximal	-1	no	62.136	62.250	PhosphoSitePlus	COSMIC	56.683	Up-regulation
CAMK_CAMKL_AMPK_PRKAA1_ST	Q9H3M7	TXNIP	Q13131	PRKAA1	S315	E316K	316	Missense	proximal	1	no	61.575	62.505	EPSD	COSMIC	56.683	Up-regulation
CAMK_CAMKL_AMPK_PRKAA1_ST	Q9H3M7	TXNIP	Q13131	PRKAA1	S315	D321Y	321	Missense	distal	6	no	61.575	61.962	EPSD	COSMIC	56.683	Up-regulation
CAMK_CAMKL_AMPK_PRKAA1_ST	Q9H3M7	TXNIP	Q13131	PRKAA1	S318	E316K	316	Missense	proximal	-2	no	61.125	62.400	EPSD	COSMIC	56.683	Up-regulation
CAMK_CAMKL_AMPK_PRKAA1_ST	Q9H3M7	TXNIP	Q13131	PRKAA1	S318	D321Y	321	Missense	distal	3	no	61.125	61.304	EPSD	COSMIC	56.683	Up-regulation
CAMK_CAMKL_AMPK_PRKAA1_ST	Q9H3M7	TXNIP	Q13131	PRKAA1	S361	I363N	363	Missense	proximal	2	no	58.179	58.548	EPSD	COSMIC;GDSC;CCLE	56.683	Up-regulation
CAMK_CAMKL_AMPK_PRKAA1_ST	Q9H3M7	TXNIP	Q13131	PRKAA1	S361	D360H	360	Missense	proximal	-1	no	58.179	58.165	EPSD	COSMIC	56.683	Down-regulation
CAMK_CAMKL_AMPK_PRKAA1_ST	Q9H3M7	TXNIP	Q13131	PRKAA1	S361	G357D	357	Missense	distal	-4	no	58.179	61.693	EPSD	COSMIC	56.683	Up-regulation
CAMK_CAMKL_AMPK_PRKAA1_ST	Q07866	KLC1	Q13131	PRKAA1	S521	V527A	527	Missense	distal	6	no	59.065	59.270	PhosphoSitePlus	COSMIC	56.683	Up-regulation
CAMK_CAMKL_AMPK_PRKAA1_ST	Q07866	KLC1	Q13131	PRKAA1	S524	V529A	529	Missense	distal	5	no	60.598	60.698	EPSD	COSMIC	56.683	Up-regulation
CAMK_CAMKL_AMPK_PRKAA1_ST	Q07866	KLC1	Q13131	PRKAA1	S524	V527A	527	Missense	distal	3	no	60.598	55.721	EPSD	COSMIC	56.683	Loss
CAMK_CAMKL_AMPK_PRKAA1_ST	Q07866	KLC1	Q13131	PRKAA1	S557	R562C	562	Missense	distal	5	no	65.509	65.510	EPSD	COSMIC	56.683	Up-regulation
CAMK_CAMKL_AMPK_PRKAA1_ST	Q07866	KLC1	Q13131	PRKAA1	S557	R562H	562	Missense	distal	5	no	65.509	65.317	EPSD	COSMIC	56.683	Down-regulation
CAMK_CAMKL_AMPK_PRKAA1_ST	Q07866	KLC1	Q13131	PRKAA1	S557	C559Y	559	Missense	proximal	2	no	65.509	66.339	EPSD	COSMIC	56.683	Up-regulation
CAMK_CAMKL_AMPK_PRKAA1_ST	Q07866	KLC1	Q13131	PRKAA1	S557	V552I	552	Missense	distal	-5	no	65.509	70.952	EPSD	COSMIC	56.683	Up-regulation
CAMK_CAMKL_AMPK_PRKAA1_ST	Q07866	KLC1	Q13131	PRKAA1	S557	A556V	556	Missense	proximal	-1	no	65.509	65.418	EPSD	COSMIC	56.683	Down-regulation
CAMK_CAMKL_AMPK_PRKAA1_ST	Q07866	KLC1	Q13131	PRKAA1	S557	S557F	557	Missense	central	0	yes	65.509	0.000	EPSD	COSMIC	56.683	Loss
CAMK_CAMKL_AMPK_PRKAA1_ST	Q07866	KLC1	Q13131	PRKAA1	S557	V552M	552	Missense	distal	-5	no	65.509	70.205	EPSD	COSMIC	56.683	Up-regulation
CAMK_CAMKL_AMPK_PRKAA1_ST	P26358	DNMT1	Q13131	PRKAA1	S91	L92F	92	Missense	proximal	1	no	58.809	64.275	EPSD	COSMIC	56.683	Up-regulation
CAMK_CAMKL_AMPK_PRKAA1_ST	P26358	DNMT1	Q13131	PRKAA1	T137	S133F	133	Missense	distal	-4	no	61.124	59.277	EPSD	COSMIC	56.683	Down-regulation
CAMK_CAMKL_AMPK_PRKAA1_ST	P26358	DNMT1	Q13131	PRKAA1	T137	R140K	140	Missense	distal	3	no	61.124	62.531	EPSD	COSMIC	56.683	Up-regulation
CAMK_CAMKL_AMPK_PRKAA1_ST	P26358	DNMT1	Q13131	PRKAA1	T137	R136C	136	Missense	proximal	-1	no	61.124	61.271	EPSD	COSMIC	56.683	Up-regulation
CAMK_CAMKL_AMPK_PRKAA1_ST	P26358	DNMT1	Q13131	PRKAA1	T137	L132P	132	Missense	distal	-5	no	61.124	56.384	EPSD	COSMIC	56.683	Loss
CAMK_CAMKL_AMPK_PRKAA1_ST	P26358	DNMT1	Q13131	PRKAA1	T137	D144N	144	Missense	distal	7	no	61.124	62.645	EPSD	COSMIC	56.683	Up-regulation
CAMK_CAMKL_AMPK_PRKAA1_ST	P26358	DNMT1	Q13131	PRKAA1	S143	R140K	140	Missense	distal	-3	no	65.756	61.115	EPSD	COSMIC	56.683	Down-regulation
CAMK_CAMKL_AMPK_PRKAA1_ST	P26358	DNMT1	Q13131	PRKAA1	S143	R136C	136	Missense	distal	-7	no	65.756	64.363	EPSD	COSMIC	56.683	Down-regulation
CAMK_CAMKL_AMPK_PRKAA1_ST	P26358	DNMT1	Q13131	PRKAA1	S143	D144N	144	Missense	proximal	1	no	65.756	65.741	EPSD	COSMIC	56.683	Down-regulation
CAMK_CAMKL_AMPK_PRKAA1_ST	P26358	DNMT1	Q13131	PRKAA1	T162	T166I	166	Missense	distal	4	no	52.811	56.834	EPSD	COSMIC	56.683	Gain
CAMK_CAMKL_AMPK_PRKAA1_ST	P26358	DNMT1	Q13131	PRKAA1	S189	S189L	189	Missense	central	0	yes	67.901	0.000	EPSD	COSMIC	56.683	Loss
CAMK_CAMKL_AMPK_PRKAA1_ST	P26358	DNMT1	Q13131	PRKAA1	S189	S192F	192	Missense	distal	3	no	67.901	66.693	EPSD	COSMIC	56.683	Down-regulation
CAMK_CAMKL_AMPK_PRKAA1_ST	P26358	DNMT1	Q13131	PRKAA1	T208	R215T	215	Missense	distal	7	no	59.207	59.547	EPSD	COSMIC;CCLE	56.683	Up-regulation
CAMK_CAMKL_AMPK_PRKAA1_ST	P26358	DNMT1	Q13131	PRKAA1	T208	R205H	205	Missense	distal	-3	no	59.207	51.351	EPSD	COSMIC	56.683	Loss
CAMK_CAMKL_AMPK_PRKAA1_ST	P26358	DNMT1	Q13131	PRKAA1	T208	R215K	215	Missense	distal	7	no	59.207	58.320	EPSD	COSMIC	56.683	Down-regulation
CAMK_CAMKL_AMPK_PRKAA1_ST	P26358	DNMT1	Q13131	PRKAA1	S209	R215T	215	Missense	distal	6	no	69.962	70.003	EPSD	COSMIC;CCLE	56.683	Up-regulation
CAMK_CAMKL_AMPK_PRKAA1_ST	P26358	DNMT1	Q13131	PRKAA1	S209	P216L	216	Missense	distal	7	no	69.962	70.502	EPSD	COSMIC	56.683	Up-regulation
CAMK_CAMKL_AMPK_PRKAA1_ST	P26358	DNMT1	Q13131	PRKAA1	S209	R205H	205	Missense	distal	-4	no	69.962	66.575	EPSD	COSMIC	56.683	Down-regulation
CAMK_CAMKL_AMPK_PRKAA1_ST	P26358	DNMT1	Q13131	PRKAA1	S209	P216Q	216	Missense	distal	7	no	69.962	71.238	EPSD	COSMIC	56.683	Up-regulation
CAMK_CAMKL_AMPK_PRKAA1_ST	P26358	DNMT1	Q13131	PRKAA1	S209	R215K	215	Missense	distal	6	no	69.962	70.014	EPSD	COSMIC	56.683	Up-regulation
CAMK_CAMKL_AMPK_PRKAA1_ST	P26358	DNMT1	Q13131	PRKAA1	S288	K291N	291	Missense	distal	3	no	57.041	58.279	EPSD	COSMIC	56.683	Up-regulation
CAMK_CAMKL_AMPK_PRKAA1_ST	P26358	DNMT1	Q13131	PRKAA1	S288	R287K	287	Missense	proximal	-1	no	57.041	56.968	EPSD	COSMIC	56.683	Down-regulation
CAMK_CAMKL_AMPK_PRKAA1_ST	P26358	DNMT1	Q13131	PRKAA1	S288	D282Y	282	Missense	distal	-6	no	57.041	52.157	EPSD	COSMIC	56.683	Loss
CAMK_CAMKL_AMPK_PRKAA1_ST	P26358	DNMT1	Q13131	PRKAA1	S288	Q289E	289	Missense	proximal	1	no	57.041	57.857	EPSD	COSMIC	56.683	Up-regulation
CAMK_CAMKL_AMPK_PRKAA1_ST	P26358	DNMT1	Q13131	PRKAA1	S288	S288N	288	Missense	central	0	yes	57.041	0.000	EPSD	COSMIC	56.683	Loss
CAMK_CAMKL_AMPK_PRKAA1_ST	P26358	DNMT1	Q13131	PRKAA1	S288	K284Q	284	Missense	distal	-4	no	57.041	58.752	EPSD	COSMIC	56.683	Up-regulation
CAMK_CAMKL_AMPK_PRKAA1_ST	P26358	DNMT1	Q13131	PRKAA1	S288	D282N	282	Missense	distal	-6	no	57.041	54.776	EPSD	COSMIC	56.683	Loss
CAMK_CAMKL_AMPK_PRKAA1_ST	P26358	DNMT1	Q13131	PRKAA1	S312	I311M	311	Missense	proximal	-1	no	57.886	57.889	EPSD	COSMIC	56.683	Up-regulation
CAMK_CAMKL_AMPK_PRKAA1_ST	P26358	DNMT1	Q13131	PRKAA1	S312	Q310R	310	Missense	proximal	-2	no	57.886	57.423	EPSD	COSMIC	56.683	Down-regulation
CAMK_CAMKL_AMPK_PRKAA1_ST	P26358	DNMT1	Q13131	PRKAA1	S312	I311V	311	Missense	proximal	-1	no	57.886	57.802	EPSD	COSMIC	56.683	Down-regulation
CAMK_CAMKL_AMPK_PRKAA1_ST	P26358	DNMT1	Q13131	PRKAA1	S312	S312F	312	Missense	central	0	yes	57.886	0.000	EPSD	COSMIC	56.683	Loss
CAMK_CAMKL_AMPK_PRKAA1_ST	P26358	DNMT1	Q13131	PRKAA1	S312	E305G	305	Missense	distal	-7	no	57.886	59.091	EPSD	COSMIC	56.683	Up-regulation
CAMK_CAMKL_AMPK_PRKAA1_ST	P26358	DNMT1	Q13131	PRKAA1	S312	V307L	307	Missense	distal	-5	no	57.886	62.750	EPSD	COSMIC	56.683	Up-regulation
CAMK_CAMKL_AMPK_PRKAA1_ST	P26358	DNMT1	Q13131	PRKAA1	S312	V307G	307	Missense	distal	-5	no	57.886	58.564	EPSD	COSMIC	56.683	Up-regulation
CAMK_CAMKL_AMPK_PRKAA1_ST	P26358	DNMT1	Q13131	PRKAA1	T327	R325H	325	Missense	proximal	-2	no	60.113	57.392	EPSD	COSMIC	56.683	Down-regulation
CAMK_CAMKL_AMPK_PRKAA1_ST	P26358	DNMT1	Q13131	PRKAA1	T327	R325L	325	Missense	proximal	-2	no	60.113	58.927	EPSD	COSMIC	56.683	Down-regulation
CAMK_CAMKL_AMPK_PRKAA1_ST	P26358	DNMT1	Q13131	PRKAA1	T327	P332L	332	Missense	distal	5	no	60.113	60.107	EPSD	COSMIC	56.683	Down-regulation
CAMK_CAMKL_AMPK_PRKAA1_ST	P26358	DNMT1	Q13131	PRKAA1	T327	E321G	321	Missense	distal	-6	no	60.113	61.000	EPSD	COSMIC	56.683	Up-regulation
CAMK_CAMKL_AMPK_PRKAA1_ST	P26358	DNMT1	Q13131	PRKAA1	T328	R325H	325	Missense	distal	-3	no	59.040	51.184	EPSD	COSMIC	56.683	Loss
CAMK_CAMKL_AMPK_PRKAA1_ST	P26358	DNMT1	Q13131	PRKAA1	T328	R325L	325	Missense	distal	-3	no	59.040	49.074	EPSD	COSMIC	56.683	Loss
CAMK_CAMKL_AMPK_PRKAA1_ST	P26358	DNMT1	Q13131	PRKAA1	T328	P332L	332	Missense	distal	4	no	59.040	65.780	EPSD	COSMIC	56.683	Up-regulation
CAMK_CAMKL_AMPK_PRKAA1_ST	P26358	DNMT1	Q13131	PRKAA1	T328	E321G	321	Missense	distal	-7	no	59.040	60.245	EPSD	COSMIC	56.683	Up-regulation
CAMK_CAMKL_AMPK_PRKAA1_ST	P26358	DNMT1	Q13131	PRKAA1	T333	R339P	339	Missense	distal	6	no	62.772	62.864	EPSD	COSMIC	56.683	Up-regulation
CAMK_CAMKL_AMPK_PRKAA1_ST	P26358	DNMT1	Q13131	PRKAA1	T333	A340T	340	Missense	distal	7	no	62.772	62.398	EPSD	COSMIC;CCLE	56.683	Down-regulation
CAMK_CAMKL_AMPK_PRKAA1_ST	P26358	DNMT1	Q13131	PRKAA1	T333	R339H	339	Missense	distal	6	no	62.772	62.877	EPSD	COSMIC	56.683	Up-regulation
CAMK_CAMKL_AMPK_PRKAA1_ST	P26358	DNMT1	Q13131	PRKAA1	T333	P332L	332	Missense	proximal	-1	no	62.772	62.843	EPSD	COSMIC	56.683	Up-regulation
CAMK_CAMKL_AMPK_PRKAA1_ST	P26358	DNMT1	Q13131	PRKAA1	T342	R339P	339	Missense	distal	-3	no	71.964	63.104	EPSD	COSMIC	56.683	Down-regulation
CAMK_CAMKL_AMPK_PRKAA1_ST	P26358	DNMT1	Q13131	PRKAA1	T342	A340T	340	Missense	proximal	-2	no	71.964	71.306	EPSD	COSMIC;CCLE	56.683	Down-regulation
CAMK_CAMKL_AMPK_PRKAA1_ST	P26358	DNMT1	Q13131	PRKAA1	T342	R339H	339	Missense	distal	-3	no	71.964	64.108	EPSD	COSMIC	56.683	Down-regulation
CAMK_CAMKL_AMPK_PRKAA1_ST	P26358	DNMT1	Q13131	PRKAA1	S714	P710S	710	Missense	distal	-4	no	62.342	63.585	EPSD	COSMIC	56.683	Up-regulation
CAMK_CAMKL_AMPK_PRKAA1_ST	P26358	DNMT1	Q13131	PRKAA1	S714	M712T	712	Missense	proximal	-2	no	62.342	62.072	EPSD	COSMIC;GDSC	56.683	Down-regulation
CAMK_CAMKL_AMPK_PRKAA1_ST	P26358	DNMT1	Q13131	PRKAA1	S714	M712L	712	Missense	proximal	-2	no	62.342	62.329	EPSD	COSMIC	56.683	Down-regulation
CAMK_CAMKL_AMPK_PRKAA1_ST	P26358	DNMT1	Q13131	PRKAA1	S878	P879S	879	Missense	proximal	1	no	57.071	57.704	EPSD	COSMIC;CCLE	56.683	Up-regulation
CAMK_CAMKL_AMPK_PRKAA1_ST	P26358	DNMT1	Q13131	PRKAA1	S878	E877K	877	Missense	proximal	-1	no	57.071	57.046	EPSD	COSMIC	56.683	Down-regulation
CAMK_CAMKL_AMPK_PRKAA1_ST	P26358	DNMT1	Q13131	PRKAA1	S878	T882I	882	Missense	distal	4	no	57.071	61.094	EPSD	COSMIC	56.683	Up-regulation
CAMK_CAMKL_AMPK_PRKAA1_ST	P26358	DNMT1	Q13131	PRKAA1	S1447	P1440T	1440	Missense	distal	-7	no	59.007	59.421	EPSD	COSMIC	56.683	Up-regulation
CAMK_CAMKL_AMPK_PRKAA1_ST	P26358	DNMT1	Q13131	PRKAA1	S1447	P1440H	1440	Missense	distal	-7	no	59.007	57.255	EPSD	COSMIC	56.683	Down-regulation
CAMK_CAMKL_AMPK_PRKAA1_ST	P26358	DNMT1	Q13131	PRKAA1	S1447	R1453M	1453	Missense	distal	6	no	59.007	59.222	EPSD	COSMIC	56.683	Up-regulation
CAMK_CAMKL_AMPK_PRKAA1_ST	P26358	DNMT1	Q13131	PRKAA1	S1447	R1445W	1445	Missense	proximal	-2	no	59.007	56.668	EPSD	COSMIC	56.683	Loss
CAMK_CAMKL_AMPK_PRKAA1_ST	P26358	DNMT1	Q13131	PRKAA1	S1447	S1447L	1447	Missense	central	0	yes	59.007	0.000	EPSD	COSMIC	56.683	Loss
CAMK_CAMKL_AMPK_PRKAA1_ST	P26358	DNMT1	Q13131	PRKAA1	S1447	R1453C	1453	Missense	distal	6	no	59.007	59.338	EPSD	COSMIC	56.683	Up-regulation
CAMK_CAMKL_AMPK_PRKAA1_ST	Q00613	HSF1	Q13131	PRKAA1	T120	T120A	120	Missense	central	0	yes	65.215	0.000	EPSD	COSMIC	56.683	Loss
CAMK_CAMKL_AMPK_PRKAA1_ST	Q00613	HSF1	Q13131	PRKAA1	S121	T120A	120	Missense	proximal	-1	no	61.132	61.211	PhosphoSitePlus	COSMIC	56.683	Up-regulation
CAMK_CAMKL_AMPK_PRKAA1_ST	Q00613	HSF1	Q13131	PRKAA1	S136	D129G	129	Missense	distal	-7	no	65.929	67.234	EPSD	COSMIC	56.683	Up-regulation
CAMK_CAMKL_AMPK_PRKAA1_ST	Q00613	HSF1	Q13131	PRKAA1	S136	R133S	133	Missense	distal	-3	no	65.929	56.534	EPSD	COSMIC	56.683	Loss
CAMK_CAMKL_AMPK_PRKAA1_ST	Q00613	HSF1	Q13131	PRKAA1	S136	V137I	137	Missense	proximal	1	no	65.929	64.486	EPSD	COSMIC	56.683	Down-regulation
CAMK_CAMKL_AMPK_PRKAA1_ST	Q00613	HSF1	Q13131	PRKAA1	S136	K139N	139	Missense	distal	3	no	65.929	67.167	EPSD	COSMIC;GDSC;CCLE	56.683	Up-regulation
CAMK_CAMKL_AMPK_PRKAA1_ST	Q00613	HSF1	Q13131	PRKAA1	S230	R227Q	227	Missense	distal	-3	no	64.109	56.165	EPSD	COSMIC;GDSC	56.683	Loss
CAMK_CAMKL_AMPK_PRKAA1_ST	Q00613	HSF1	Q13131	PRKAA1	S230	G236S	236	Missense	distal	6	no	64.109	64.337	EPSD	COSMIC;CCLE	56.683	Up-regulation
CAMK_CAMKL_AMPK_PRKAA1_ST	Q00613	HSF1	Q13131	PRKAA1	S230	S237L	237	Missense	distal	7	no	64.109	64.151	EPSD	COSMIC	56.683	Up-regulation
CAMK_CAMKL_AMPK_PRKAA1_ST	Q00613	HSF1	Q13131	PRKAA1	S244	S237L	237	Missense	distal	-7	no	59.384	56.956	EPSD	COSMIC	56.683	Down-regulation
CAMK_CAMKL_AMPK_PRKAA1_ST	Q00613	HSF1	Q13131	PRKAA1	S244	P239H	239	Missense	distal	-5	no	59.384	57.567	EPSD	COSMIC	56.683	Down-regulation
CAMK_CAMKL_AMPK_PRKAA1_ST	Q00613	HSF1	Q13131	PRKAA1	S244	S244F	244	Missense	central	0	yes	59.384	0.000	EPSD	COSMIC	56.683	Loss
CAMK_CAMKL_AMPK_PRKAA1_ST	Q00613	HSF1	Q13131	PRKAA1	S248	S244F	244	Missense	distal	-4	no	58.601	56.754	EPSD	COSMIC	56.683	Down-regulation
CAMK_CAMKL_AMPK_PRKAA1_ST	Q00613	HSF1	Q13131	PRKAA1	S290	R287K	287	Missense	distal	-3	no	68.858	64.216	EPSD	COSMIC	56.683	Down-regulation
CAMK_CAMKL_AMPK_PRKAA1_ST	Q00613	HSF1	Q13131	PRKAA1	S290	S283N	283	Missense	distal	-7	no	68.858	67.767	EPSD	COSMIC	56.683	Down-regulation
CAMK_CAMKL_AMPK_PRKAA1_ST	Q00613	HSF1	Q13131	PRKAA1	S320	P318T	318	Missense	proximal	-2	no	66.156	62.924	EPSD	COSMIC	56.683	Down-regulation
CAMK_CAMKL_AMPK_PRKAA1_ST	Q00613	HSF1	Q13131	PRKAA1	S320	P327Q	327	Missense	distal	7	no	66.156	67.432	EPSD	COSMIC	56.683	Up-regulation
CAMK_CAMKL_AMPK_PRKAA1_ST	Q00613	HSF1	Q13131	PRKAA1	S363	S363P	363	Missense	central	0	yes	58.558	0.000	EPSD	COSMIC	56.683	Loss
CAMK_CAMKL_AMPK_PRKAA1_ST	Q00613	HSF1	Q13131	PRKAA1	S363	P365Q	365	Missense	proximal	2	no	58.558	57.632	EPSD	COSMIC	56.683	Down-regulation
CAMK_CAMKL_AMPK_PRKAA1_ST	Q00613	HSF1	Q13131	PRKAA1	S363	D356N	356	Missense	distal	-7	no	58.558	58.352	EPSD	COSMIC	56.683	Down-regulation
CAMK_CAMKL_AMPK_PRKAA1_ST	Q00613	HSF1	Q13131	PRKAA1	S363	P365T	365	Missense	proximal	2	no	58.558	58.261	EPSD	COSMIC	56.683	Down-regulation
CAMK_CAMKL_AMPK_PRKAA1_ST	Q00613	HSF1	Q13131	PRKAA1	S363	E358K	358	Missense	distal	-5	no	58.558	55.910	EPSD	COSMIC	56.683	Loss
CAMK_CAMKL_AMPK_PRKAA1_ST	Q00613	HSF1	Q13131	PRKAA1	S363	P365L	365	Missense	proximal	2	no	58.558	57.958	EPSD	COSMIC	56.683	Down-regulation
CAMK_CAMKL_AMPK_PRKAA1_ST	Q00613	HSF1	Q13131	PRKAA1	S438	S434N	434	Missense	distal	-4	no	60.281	55.481	EPSD	COSMIC	56.683	Loss
CAMK_CAMKL_AMPK_PRKAA1_ST	Q16875	PFKFB3	Q13131	PRKAA1	T36	V39I	39	Missense	distal	3	no	64.333	61.059	EPSD	COSMIC	56.683	Down-regulation
CAMK_CAMKL_AMPK_PRKAA1_ST	Q16875	PFKFB3	Q13131	PRKAA1	T36	P35S	35	Missense	proximal	-1	no	64.333	64.379	EPSD	COSMIC	56.683	Up-regulation
CAMK_CAMKL_AMPK_PRKAA1_ST	Q16875	PFKFB3	Q13131	PRKAA1	T36	G42E	42	Missense	distal	6	no	64.333	64.735	EPSD	COSMIC	56.683	Up-regulation
CAMK_CAMKL_AMPK_PRKAA1_ST	Q16875	PFKFB3	Q13131	PRKAA1	S83	S84F	84	Missense	proximal	1	no	66.571	71.111	EPSD	COSMIC	56.683	Up-regulation
CAMK_CAMKL_AMPK_PRKAA1_ST	Q16875	PFKFB3	Q13131	PRKAA1	S83	R89H	89	Missense	distal	6	no	66.571	66.676	EPSD	COSMIC	56.683	Up-regulation
CAMK_CAMKL_AMPK_PRKAA1_ST	Q16875	PFKFB3	Q13131	PRKAA1	S83	A78T	78	Missense	distal	-5	no	66.571	64.579	EPSD	COSMIC	56.683	Down-regulation
CAMK_CAMKL_AMPK_PRKAA1_ST	Q16875	PFKFB3	Q13131	PRKAA1	S83	R89L	89	Missense	distal	6	no	66.571	66.811	EPSD	COSMIC	56.683	Up-regulation
CAMK_CAMKL_AMPK_PRKAA1_ST	Q16875	PFKFB3	Q13131	PRKAA1	S83	R89S	89	Missense	distal	6	no	66.571	66.678	EPSD	COSMIC	56.683	Up-regulation
CAMK_CAMKL_AMPK_PRKAA1_ST	Q16875	PFKFB3	Q13131	PRKAA1	S211	S211L	211	Missense	central	0	yes	63.029	0.000	EPSD	COSMIC	56.683	Loss
CAMK_CAMKL_AMPK_PRKAA1_ST	Q16875	PFKFB3	Q13131	PRKAA1	S211	S211P	211	Missense	central	0	yes	63.029	0.000	EPSD	COSMIC	56.683	Loss
CAMK_CAMKL_AMPK_PRKAA1_ST	Q16875	PFKFB3	Q13131	PRKAA1	S211	S211R	211	Missense	central	0	yes	63.029	0.000	EPSD	COSMIC	56.683	Loss
CAMK_CAMKL_AMPK_PRKAA1_ST	Q16875	PFKFB3	Q13131	PRKAA1	S211	S211N	211	Missense	central	0	yes	63.029	0.000	EPSD	COSMIC	56.683	Loss
CAMK_CAMKL_AMPK_PRKAA1_ST	Q16875	PFKFB3	Q13131	PRKAA1	T359	G360R	360	Missense	proximal	1	no	57.676	56.102	EPSD	COSMIC	56.683	Loss
CAMK_CAMKL_AMPK_PRKAA1_ST	Q16875	PFKFB3	Q13131	PRKAA1	T359	R356C	356	Missense	distal	-3	no	57.676	43.529	EPSD	COSMIC	56.683	Loss
CAMK_CAMKL_AMPK_PRKAA1_ST	Q16875	PFKFB3	Q13131	PRKAA1	T359	Y354C	354	Missense	distal	-5	no	57.676	60.183	EPSD	COSMIC	56.683	Up-regulation
CAMK_CAMKL_AMPK_PRKAA1_ST	Q16875	PFKFB3	Q13131	PRKAA1	S461	S467N	467	Missense	distal	6	no	63.780	63.663	PhosphoSitePlus	COSMIC;GDSC;CCLE	56.683	Down-regulation
CAMK_CAMKL_AMPK_PRKAA1_ST	Q16875	PFKFB3	Q13131	PRKAA1	S461	S467L	467	Missense	distal	6	no	63.780	63.914	PhosphoSitePlus	COSMIC	56.683	Up-regulation
CAMK_CAMKL_AMPK_PRKAA1_ST	Q9P2M7	CGN	Q13131	PRKAA1	T217	R221L	221	Missense	distal	4	no	53.356	58.837	EPSD	COSMIC	56.683	Gain
CAMK_CAMKL_AMPK_PRKAA1_ST	Q9P2M7	CGN	Q13131	PRKAA1	S1080	E1084K	1084	Missense	distal	4	no	57.215	62.971	EPSD	COSMIC	56.683	Up-regulation
CAMK_CAMKL_AMPK_PRKAA1_ST	Q8IXJ6	SIRT2	Q13131	PRKAA1	S53	T48I	48	Missense	distal	-5	no	54.981	61.223	EPSD	COSMIC	56.683	Gain
CAMK_CAMKL_AMPK_PRKAA1_ST	Q8IXJ6	SIRT2	Q13131	PRKAA1	S100	P99L	99	Missense	proximal	-1	no	56.799	56.870	EPSD	COSMIC	56.683	Up-regulation
CAMK_CAMKL_AMPK_PRKAA1_ST	Q8IXJ6	SIRT2	Q13131	PRKAA1	T101	P99L	99	Missense	proximal	-2	no	58.596	55.621	PhosphoSitePlus	COSMIC	56.683	Loss
CAMK_CAMKL_AMPK_PRKAA1_ST	P14859	POU2F1	Q13131	PRKAA1	S78	S72G	72	Missense	distal	-6	no	57.356	56.862	EPSD	COSMIC	56.683	Down-regulation
CAMK_CAMKL_AMPK_PRKAA1_ST	P14859	POU2F1	Q13131	PRKAA1	S78	Q83H	83	Missense	distal	5	no	57.356	57.117	EPSD	COSMIC	56.683	Down-regulation
CAMK_CAMKL_AMPK_PRKAA1_ST	P14859	POU2F1	Q13131	PRKAA1	S78	P84T	84	Missense	distal	6	no	57.356	57.305	EPSD	COSMIC	56.683	Down-regulation
CAMK_CAMKL_AMPK_PRKAA1_ST	P14859	POU2F1	Q13131	PRKAA1	S78	D80N	80	Missense	proximal	2	no	57.356	56.469	EPSD	COSMIC	56.683	Loss
CAMK_CAMKL_AMPK_PRKAA1_ST	P14859	POU2F1	Q13131	PRKAA1	S78	S72F	72	Missense	distal	-6	no	57.356	57.458	EPSD	COSMIC;GDSC	56.683	Up-regulation
CAMK_CAMKL_AMPK_PRKAA1_ST	P14859	POU2F1	Q13131	PRKAA1	S335	A331V	331	Missense	distal	-4	no	69.234	68.241	PhosphoSitePlus	COSMIC	56.683	Down-regulation
CAMK_CAMKL_AMPK_PRKAA1_ST	P14859	POU2F1	Q13131	PRKAA1	S357	E354D	354	Missense	distal	-3	no	57.021	55.650	EPSD	COSMIC	56.683	Loss
CAMK_CAMKL_AMPK_PRKAA1_ST	P14859	POU2F1	Q13131	PRKAA1	S358	E354D	354	Missense	distal	-4	no	67.866	67.828	EPSD	COSMIC	56.683	Down-regulation
CAMK_CAMKL_AMPK_PRKAA1_ST	P14859	POU2F1	Q13131	PRKAA1	S358	P365S	365	Missense	distal	7	no	67.866	68.364	EPSD	COSMIC	56.683	Up-regulation
CAMK_CAMKL_AMPK_PRKAA1_ST	P14859	POU2F1	Q13131	PRKAA1	T384	R391H	391	Missense	distal	7	no	58.007	57.281	EPSD	COSMIC	56.683	Down-regulation
CAMK_CAMKL_AMPK_PRKAA1_ST	P14859	POU2F1	Q13131	PRKAA1	T384	N389S	389	Missense	distal	5	no	58.007	58.045	EPSD	COSMIC	56.683	Up-regulation
CAMK_CAMKL_AMPK_PRKAA1_ST	Q13363	CTBP1	Q13131	PRKAA1	S100	D106E	106	Missense	distal	6	no	58.947	59.420	EPSD	COSMIC	56.683	Up-regulation
CAMK_CAMKL_AMPK_PRKAA1_ST	Q13363	CTBP1	Q13131	PRKAA1	S100	D103V	103	Missense	distal	3	no	58.947	59.103	EPSD	COSMIC	56.683	Up-regulation
CAMK_CAMKL_AMPK_PRKAA1_ST	Q13363	CTBP1	Q13131	PRKAA1	S158	E160K	160	Missense	proximal	2	no	62.373	61.980	PhosphoSitePlus	COSMIC	56.683	Down-regulation
CAMK_CAMKL_AMPK_PRKAA1_ST	Q13363	CTBP1	Q13131	PRKAA1	S158	E152G	152	Missense	distal	-6	no	62.373	63.260	PhosphoSitePlus	COSMIC	56.683	Up-regulation
CAMK_CAMKL_AMPK_PRKAA1_ST	Q13363	CTBP1	Q13131	PRKAA1	S158	E164K	164	Missense	distal	6	no	62.373	62.145	PhosphoSitePlus	COSMIC;CCLE	56.683	Down-regulation
CAMK_CAMKL_AMPK_PRKAA1_ST	Q14247	CTTN	Q13131	PRKAA1	T76	K70N	70	Missense	distal	-6	no	56.517	57.648	EPSD	COSMIC	56.683	Gain
CAMK_CAMKL_AMPK_PRKAA1_ST	Q14247	CTTN	Q13131	PRKAA1	S282	R279W	279	Missense	distal	-3	no	65.321	-27.679	EPSD	COSMIC	56.683	Loss
CAMK_CAMKL_AMPK_PRKAA1_ST	Q14247	CTTN	Q13131	PRKAA1	S282	F287L	287	Missense	distal	5	no	65.321	65.482	EPSD	COSMIC	56.683	Up-regulation
CAMK_CAMKL_AMPK_PRKAA1_ST	Q14247	CTTN	Q13131	PRKAA1	S282	S277L	277	Missense	distal	-5	no	65.321	69.503	EPSD	COSMIC	56.683	Up-regulation
CAMK_CAMKL_AMPK_PRKAA1_ST	Q14247	CTTN	Q13131	PRKAA1	S332	E325D	325	Missense	distal	-7	no	56.880	56.781	EPSD	COSMIC	56.683	Down-regulation
CAMK_CAMKL_AMPK_PRKAA1_ST	Q14247	CTTN	Q13131	PRKAA1	S332	V330E	330	Missense	proximal	-2	no	56.880	55.735	EPSD	COSMIC	56.683	Loss
CAMK_CAMKL_AMPK_PRKAA1_ST	Q14247	CTTN	Q13131	PRKAA1	S332	T328A	328	Missense	distal	-4	no	56.880	57.736	EPSD	COSMIC	56.683	Up-regulation
CAMK_CAMKL_AMPK_PRKAA1_ST	Q14247	CTTN	Q13131	PRKAA1	T401	Q394K	394	Missense	distal	-7	no	59.063	60.489	PhosphoSitePlus	COSMIC	56.683	Up-regulation
CAMK_CAMKL_AMPK_PRKAA1_ST	Q14247	CTTN	Q13131	PRKAA1	T401	R396T	396	Missense	distal	-5	no	59.063	54.576	PhosphoSitePlus	COSMIC	56.683	Loss
CAMK_CAMKL_AMPK_PRKAA1_ST	Q14247	CTTN	Q13131	PRKAA1	S417	T411I	411	Missense	distal	-6	no	57.091	53.952	EPSD	COSMIC	56.683	Loss
CAMK_CAMKL_AMPK_PRKAA1_ST	Q14247	CTTN	Q13131	PRKAA1	S417	V420I	420	Missense	distal	3	no	57.091	53.817	EPSD	COSMIC	56.683	Loss
CAMK_CAMKL_AMPK_PRKAA1_ST	Q14247	CTTN	Q13131	PRKAA1	S438	P442L	442	Missense	distal	4	no	53.023	59.763	EPSD	COSMIC	56.683	Gain
CAMK_CAMKL_AMPK_PRKAA1_ST	Q14247	CTTN	Q13131	PRKAA1	S447	P442L	442	Missense	distal	-5	no	52.854	57.595	EPSD	COSMIC	56.683	Gain
CAMK_CAMKL_AMPK_PRKAA1_ST	Q9NZQ7	CD274	Q13131	PRKAA1	S279	T285A	285	Missense	distal	6	no	62.501	62.661	EPSD	COSMIC	56.683	Up-regulation
CAMK_CAMKL_AMPK_PRKAA1_ST	Q9NZQ7	CD274	Q13131	PRKAA1	S279	T277K	277	Missense	proximal	-2	no	62.501	65.322	EPSD	COSMIC	56.683	Up-regulation
CAMK_CAMKL_AMPK_PRKAA1_ST	Q9NZQ7	CD274	Q13131	PRKAA1	S279	C272Y	272	Missense	distal	-7	no	62.501	62.750	EPSD	COSMIC	56.683	Up-regulation
CAMK_CAMKL_AMPK_PRKAA1_ST	P15056	BRAF	Q13131	PRKAA1	S151	V157I	157	Missense	distal	6	no	59.762	59.551	EPSD	COSMIC;CCLE	56.683	Down-regulation
CAMK_CAMKL_AMPK_PRKAA1_ST	P15056	BRAF	Q13131	PRKAA1	S151	S151A	151	Missense	central	0	yes	59.762	0.000	EPSD	COSMIC	56.683	Loss
CAMK_CAMKL_AMPK_PRKAA1_ST	P15056	BRAF	Q13131	PRKAA1	S151	P149H	149	Missense	proximal	-2	no	59.762	55.253	EPSD	COSMIC	56.683	Loss
CAMK_CAMKL_AMPK_PRKAA1_ST	P15056	BRAF	Q13131	PRKAA1	S363	R360Q	360	Missense	distal	-3	no	60.159	52.215	EPSD	COSMIC	56.683	Loss
CAMK_CAMKL_AMPK_PRKAA1_ST	P15056	BRAF	Q13131	PRKAA1	S363	S365L	365	Missense	proximal	2	no	60.159	60.103	EPSD	COSMIC	56.683	Down-regulation
CAMK_CAMKL_AMPK_PRKAA1_ST	P15056	BRAF	Q13131	PRKAA1	S363	R362L	362	Missense	proximal	-1	no	60.159	60.218	EPSD	COSMIC	56.683	Up-regulation
CAMK_CAMKL_AMPK_PRKAA1_ST	P15056	BRAF	Q13131	PRKAA1	S363	Q356K	356	Missense	distal	-7	no	60.159	61.586	EPSD	COSMIC	56.683	Up-regulation
CAMK_CAMKL_AMPK_PRKAA1_ST	P15056	BRAF	Q13131	PRKAA1	S363	F357S	357	Missense	distal	-6	no	60.159	60.056	EPSD	COSMIC	56.683	Down-regulation
CAMK_CAMKL_AMPK_PRKAA1_ST	P15056	BRAF	Q13131	PRKAA1	S365	R360Q	360	Missense	distal	-5	no	71.119	65.437	EPSD	COSMIC	56.683	Down-regulation
CAMK_CAMKL_AMPK_PRKAA1_ST	P15056	BRAF	Q13131	PRKAA1	S365	S365L	365	Missense	central	0	yes	71.119	0.000	EPSD	COSMIC	56.683	Loss
CAMK_CAMKL_AMPK_PRKAA1_ST	P15056	BRAF	Q13131	PRKAA1	S365	R362L	362	Missense	distal	-3	no	71.119	61.153	EPSD	COSMIC	56.683	Down-regulation
CAMK_CAMKL_AMPK_PRKAA1_ST	P15056	BRAF	Q13131	PRKAA1	S430	S428L	428	Missense	proximal	-2	no	63.157	60.731	EPSD	COSMIC	56.683	Down-regulation
CAMK_CAMKL_AMPK_PRKAA1_ST	P15056	BRAF	Q13131	PRKAA1	S430	R424L	424	Missense	distal	-6	no	63.157	62.996	EPSD	COSMIC	56.683	Down-regulation
CAMK_CAMKL_AMPK_PRKAA1_ST	P15056	BRAF	Q13131	PRKAA1	T440	S447N	447	Missense	distal	7	no	58.124	58.426	EPSD	COSMIC	56.683	Up-regulation
CAMK_CAMKL_AMPK_PRKAA1_ST	P15056	BRAF	Q13131	PRKAA1	T440	R443I	443	Missense	distal	3	no	58.124	56.397	EPSD	COSMIC	56.683	Loss
CAMK_CAMKL_AMPK_PRKAA1_ST	P15056	BRAF	Q13131	PRKAA1	T440	R443T	443	Missense	distal	3	no	58.124	57.710	EPSD	COSMIC	56.683	Down-regulation
CAMK_CAMKL_AMPK_PRKAA1_ST	P15056	BRAF	Q13131	PRKAA1	T440	K439T	439	Missense	proximal	-1	no	58.124	58.173	EPSD	COSMIC	56.683	Up-regulation
CAMK_CAMKL_AMPK_PRKAA1_ST	P15056	BRAF	Q13131	PRKAA1	T440	G442S	442	Missense	proximal	2	no	58.124	58.633	EPSD	COSMIC	56.683	Up-regulation
CAMK_CAMKL_AMPK_PRKAA1_ST	P15056	BRAF	Q13131	PRKAA1	T440	T440P	440	Missense	central	0	yes	58.124	0.000	EPSD	COSMIC	56.683	Loss
CAMK_CAMKL_AMPK_PRKAA1_ST	P15056	BRAF	Q13131	PRKAA1	T440	L441V	441	Missense	proximal	1	no	58.124	58.914	EPSD	COSMIC	56.683	Up-regulation
CAMK_CAMKL_AMPK_PRKAA1_ST	P15056	BRAF	Q13131	PRKAA1	T440	K439Q	439	Missense	proximal	-1	no	58.124	58.226	EPSD	COSMIC	56.683	Up-regulation
CAMK_CAMKL_AMPK_PRKAA1_ST	P15056	BRAF	Q13131	PRKAA1	T440	S447C	447	Missense	distal	7	no	58.124	57.571	EPSD	COSMIC	56.683	Down-regulation
CAMK_CAMKL_AMPK_PRKAA1_ST	P15056	BRAF	Q13131	PRKAA1	T440	G442D	442	Missense	proximal	2	no	58.124	59.276	EPSD	COSMIC	56.683	Up-regulation
CAMK_CAMKL_AMPK_PRKAA1_ST	P15056	BRAF	Q13131	PRKAA1	T440	T440I	440	Missense	central	0	yes	58.124	0.000	EPSD	COSMIC	56.683	Loss
CAMK_CAMKL_AMPK_PRKAA1_ST	P15056	BRAF	Q13131	PRKAA1	S446	S447N	447	Missense	proximal	1	no	72.355	71.502	EPSD	COSMIC	56.683	Down-regulation
CAMK_CAMKL_AMPK_PRKAA1_ST	P15056	BRAF	Q13131	PRKAA1	S446	P453H	453	Missense	distal	7	no	72.355	71.541	EPSD	COSMIC	56.683	Down-regulation
CAMK_CAMKL_AMPK_PRKAA1_ST	P15056	BRAF	Q13131	PRKAA1	S446	P453T	453	Missense	distal	7	no	72.355	72.607	EPSD	COSMIC	56.683	Up-regulation
CAMK_CAMKL_AMPK_PRKAA1_ST	P15056	BRAF	Q13131	PRKAA1	S446	R443I	443	Missense	distal	-3	no	72.355	58.957	EPSD	COSMIC	56.683	Down-regulation
CAMK_CAMKL_AMPK_PRKAA1_ST	P15056	BRAF	Q13131	PRKAA1	S446	W450L	450	Missense	distal	4	no	72.355	74.587	EPSD	COSMIC	56.683	Up-regulation
CAMK_CAMKL_AMPK_PRKAA1_ST	P15056	BRAF	Q13131	PRKAA1	S446	R443T	443	Missense	distal	-3	no	72.355	58.244	EPSD	COSMIC	56.683	Down-regulation
CAMK_CAMKL_AMPK_PRKAA1_ST	P15056	BRAF	Q13131	PRKAA1	S446	K439T	439	Missense	distal	-7	no	72.355	69.895	EPSD	COSMIC	56.683	Down-regulation
CAMK_CAMKL_AMPK_PRKAA1_ST	P15056	BRAF	Q13131	PRKAA1	S446	G442S	442	Missense	distal	-4	no	72.355	74.899	EPSD	COSMIC	56.683	Up-regulation
CAMK_CAMKL_AMPK_PRKAA1_ST	P15056	BRAF	Q13131	PRKAA1	S446	T440P	440	Missense	distal	-6	no	72.355	72.239	EPSD	COSMIC	56.683	Down-regulation
CAMK_CAMKL_AMPK_PRKAA1_ST	P15056	BRAF	Q13131	PRKAA1	S446	L441V	441	Missense	distal	-5	no	72.355	67.492	EPSD	COSMIC	56.683	Down-regulation
CAMK_CAMKL_AMPK_PRKAA1_ST	P15056	BRAF	Q13131	PRKAA1	S446	K439Q	439	Missense	distal	-7	no	72.355	70.929	EPSD	COSMIC	56.683	Down-regulation
CAMK_CAMKL_AMPK_PRKAA1_ST	P15056	BRAF	Q13131	PRKAA1	S446	S447C	447	Missense	proximal	1	no	72.355	71.693	EPSD	COSMIC	56.683	Down-regulation
CAMK_CAMKL_AMPK_PRKAA1_ST	P15056	BRAF	Q13131	PRKAA1	S446	D449E	449	Missense	distal	3	no	72.355	70.646	EPSD	COSMIC	56.683	Down-regulation
CAMK_CAMKL_AMPK_PRKAA1_ST	P15056	BRAF	Q13131	PRKAA1	S446	G442D	442	Missense	distal	-4	no	72.355	75.869	EPSD	COSMIC	56.683	Up-regulation
CAMK_CAMKL_AMPK_PRKAA1_ST	P15056	BRAF	Q13131	PRKAA1	S446	T440I	440	Missense	distal	-6	no	72.355	69.216	EPSD	COSMIC	56.683	Down-regulation
CAMK_CAMKL_AMPK_PRKAA1_ST	P15056	BRAF	Q13131	PRKAA1	S446	W450R	450	Missense	distal	4	no	72.355	69.105	EPSD	COSMIC	56.683	Down-regulation
CAMK_CAMKL_AMPK_PRKAA1_ST	P15056	BRAF	Q13131	PRKAA1	S446	D449Y	449	Missense	distal	3	no	72.355	72.535	EPSD	COSMIC	56.683	Up-regulation
CAMK_CAMKL_AMPK_PRKAA1_ST	P15056	BRAF	Q13131	PRKAA1	S447	S447N	447	Missense	central	0	yes	63.427	0.000	EPSD	COSMIC	56.683	Loss
CAMK_CAMKL_AMPK_PRKAA1_ST	P15056	BRAF	Q13131	PRKAA1	S447	P453H	453	Missense	distal	6	no	63.427	63.441	EPSD	COSMIC	56.683	Up-regulation
CAMK_CAMKL_AMPK_PRKAA1_ST	P15056	BRAF	Q13131	PRKAA1	S447	P453T	453	Missense	distal	6	no	63.427	63.376	EPSD	COSMIC	56.683	Down-regulation
CAMK_CAMKL_AMPK_PRKAA1_ST	P15056	BRAF	Q13131	PRKAA1	S447	R443I	443	Missense	distal	-4	no	63.427	59.564	EPSD	COSMIC	56.683	Down-regulation
CAMK_CAMKL_AMPK_PRKAA1_ST	P15056	BRAF	Q13131	PRKAA1	S447	W450L	450	Missense	distal	3	no	63.427	60.038	EPSD	COSMIC	56.683	Down-regulation
CAMK_CAMKL_AMPK_PRKAA1_ST	P15056	BRAF	Q13131	PRKAA1	S447	R443T	443	Missense	distal	-4	no	63.427	61.107	EPSD	COSMIC	56.683	Down-regulation
CAMK_CAMKL_AMPK_PRKAA1_ST	P15056	BRAF	Q13131	PRKAA1	S447	G442S	442	Missense	distal	-5	no	63.427	63.430	EPSD	COSMIC	56.683	Up-regulation
CAMK_CAMKL_AMPK_PRKAA1_ST	P15056	BRAF	Q13131	PRKAA1	S447	T440P	440	Missense	distal	-7	no	63.427	63.013	EPSD	COSMIC	56.683	Down-regulation
CAMK_CAMKL_AMPK_PRKAA1_ST	P15056	BRAF	Q13131	PRKAA1	S447	D454N	454	Missense	distal	7	no	63.427	64.948	EPSD	COSMIC	56.683	Up-regulation
CAMK_CAMKL_AMPK_PRKAA1_ST	P15056	BRAF	Q13131	PRKAA1	S447	L441V	441	Missense	distal	-6	no	63.427	61.934	EPSD	COSMIC	56.683	Down-regulation
CAMK_CAMKL_AMPK_PRKAA1_ST	P15056	BRAF	Q13131	PRKAA1	S447	S447C	447	Missense	central	0	yes	63.427	0.000	EPSD	COSMIC	56.683	Loss
CAMK_CAMKL_AMPK_PRKAA1_ST	P15056	BRAF	Q13131	PRKAA1	S447	D449E	449	Missense	proximal	2	no	63.427	63.388	EPSD	COSMIC	56.683	Down-regulation
CAMK_CAMKL_AMPK_PRKAA1_ST	P15056	BRAF	Q13131	PRKAA1	S447	G442D	442	Missense	distal	-5	no	63.427	62.578	EPSD	COSMIC	56.683	Down-regulation
CAMK_CAMKL_AMPK_PRKAA1_ST	P15056	BRAF	Q13131	PRKAA1	S447	T440I	440	Missense	distal	-7	no	63.427	62.929	EPSD	COSMIC	56.683	Down-regulation
CAMK_CAMKL_AMPK_PRKAA1_ST	P15056	BRAF	Q13131	PRKAA1	S447	W450R	450	Missense	distal	3	no	63.427	61.369	EPSD	COSMIC	56.683	Down-regulation
CAMK_CAMKL_AMPK_PRKAA1_ST	P15056	BRAF	Q13131	PRKAA1	S447	D449Y	449	Missense	proximal	2	no	63.427	62.317	EPSD	COSMIC	56.683	Down-regulation
CAMK_CAMKL_AMPK_PRKAA1_ST	P15056	BRAF	Q13131	PRKAA1	T458	G455R	455	Missense	distal	-3	no	53.251	62.286	EPSD	COSMIC	56.683	Gain
CAMK_CAMKL_AMPK_PRKAA1_ST	P15056	BRAF	Q13131	PRKAA1	S465	G469S	469	Missense	distal	4	no	55.618	56.714	EPSD	COSMIC	56.683	Gain
CAMK_CAMKL_AMPK_PRKAA1_ST	P15056	BRAF	Q13131	PRKAA1	S465	V459L	459	Missense	distal	-6	no	55.618	57.112	EPSD	COSMIC	56.683	Gain
CAMK_CAMKL_AMPK_PRKAA1_ST	P15056	BRAF	Q13131	PRKAA1	S465	G469L	469	Missense	distal	4	no	55.618	63.302	EPSD	COSMIC	56.683	Gain
CAMK_CAMKL_AMPK_PRKAA1_ST	P15056	BRAF	Q13131	PRKAA1	S465	F468S	468	Missense	distal	3	no	55.618	56.827	EPSD	COSMIC	56.683	Gain
CAMK_CAMKL_AMPK_PRKAA1_ST	P15056	BRAF	Q13131	PRKAA1	S465	I463N	463	Missense	proximal	-2	no	55.618	56.836	EPSD	COSMIC	56.683	Gain
CAMK_CAMKL_AMPK_PRKAA1_ST	P15056	BRAF	Q13131	PRKAA1	S465	G460R	460	Missense	distal	-5	no	55.618	58.627	EPSD	COSMIC	56.683	Gain
CAMK_CAMKL_AMPK_PRKAA1_ST	P15056	BRAF	Q13131	PRKAA1	S465	I463S	463	Missense	proximal	-2	no	55.618	57.496	EPSD	COSMIC	56.683	Gain
CAMK_CAMKL_AMPK_PRKAA1_ST	P15056	BRAF	Q13131	PRKAA1	S467	G464R	464	Missense	distal	-3	no	54.974	64.009	EPSD	COSMIC	56.683	Gain
CAMK_CAMKL_AMPK_PRKAA1_ST	P15056	BRAF	Q13131	PRKAA1	S467	R462I	462	Missense	distal	-5	no	54.974	56.729	EPSD	COSMIC	56.683	Gain
CAMK_CAMKL_AMPK_PRKAA1_ST	P15056	BRAF	Q13131	PRKAA1	S467	I463S	463	Missense	distal	-4	no	54.974	57.772	EPSD	COSMIC	56.683	Gain
CAMK_CAMKL_AMPK_PRKAA1_ST	P15056	BRAF	Q13131	PRKAA1	S607	W604G	604	Missense	distal	-3	no	-26.769	57.196	EPSD	COSMIC	56.683	Gain
CAMK_CAMKL_AMPK_PRKAA1_ST	P15056	BRAF	Q13131	PRKAA1	S607	W604S	604	Missense	distal	-3	no	-26.769	56.836	EPSD	COSMIC	56.683	Gain
CAMK_CAMKL_AMPK_PRKAA1_ST	P15056	BRAF	Q13131	PRKAA1	S607	W604R	604	Missense	distal	-3	no	-26.769	66.231	EPSD	COSMIC	56.683	Gain
CAMK_CAMKL_AMPK_PRKAA1_ST	P15056	BRAF	Q13131	PRKAA1	S614	Q609R	609	Missense	distal	-5	no	54.769	60.451	EPSD	COSMIC	56.683	Gain
CAMK_CAMKL_AMPK_PRKAA1_ST	P15056	BRAF	Q13131	PRKAA1	S614	H608D	608	Missense	distal	-6	no	54.769	58.217	EPSD	COSMIC	56.683	Gain
CAMK_CAMKL_AMPK_PRKAA1_ST	P15056	BRAF	Q13131	PRKAA1	S616	L618S	618	Missense	proximal	2	no	63.466	63.522	EPSD	COSMIC	56.683	Up-regulation
CAMK_CAMKL_AMPK_PRKAA1_ST	P15056	BRAF	Q13131	PRKAA1	S616	S616F	616	Missense	central	0	yes	63.466	0.000	EPSD	COSMIC	56.683	Loss
CAMK_CAMKL_AMPK_PRKAA1_ST	P15056	BRAF	Q13131	PRKAA1	S616	G615R	615	Missense	proximal	-1	no	63.466	63.427	EPSD	COSMIC	56.683	Down-regulation
CAMK_CAMKL_AMPK_PRKAA1_ST	P15056	BRAF	Q13131	PRKAA1	S616	L618W	618	Missense	proximal	2	no	63.466	63.701	EPSD	COSMIC	56.683	Up-regulation
CAMK_CAMKL_AMPK_PRKAA1_ST	P15056	BRAF	Q13131	PRKAA1	S616	M620I	620	Missense	distal	4	no	63.466	62.966	EPSD	COSMIC	56.683	Down-regulation
CAMK_CAMKL_AMPK_PRKAA1_ST	P15056	BRAF	Q13131	PRKAA1	S616	F610S	610	Missense	distal	-6	no	63.466	63.363	EPSD	COSMIC	56.683	Down-regulation
CAMK_CAMKL_AMPK_PRKAA1_ST	P15056	BRAF	Q13131	PRKAA1	S616	Q609R	609	Missense	distal	-7	no	63.466	63.289	EPSD	COSMIC	56.683	Down-regulation
CAMK_CAMKL_AMPK_PRKAA1_ST	P15056	BRAF	Q13131	PRKAA1	S616	E611D	611	Missense	distal	-5	no	63.466	60.050	EPSD	COSMIC	56.683	Down-regulation
CAMK_CAMKL_AMPK_PRKAA1_ST	P15056	BRAF	Q13131	PRKAA1	S616	Q612R	612	Missense	distal	-4	no	63.466	64.934	EPSD	COSMIC	56.683	Up-regulation
CAMK_CAMKL_AMPK_PRKAA1_ST	P15056	BRAF	Q13131	PRKAA1	S616	F610I	610	Missense	distal	-6	no	63.466	60.690	EPSD	COSMIC	56.683	Down-regulation
CAMK_CAMKL_AMPK_PRKAA1_ST	P15056	BRAF	Q13131	PRKAA1	S616	S616P	616	Missense	central	0	yes	63.466	0.000	EPSD	COSMIC	56.683	Loss
CAMK_CAMKL_AMPK_PRKAA1_ST	P15056	BRAF	Q13131	PRKAA1	S616	S614F	614	Missense	proximal	-2	no	63.466	61.267	EPSD	COSMIC	56.683	Down-regulation
CAMK_CAMKL_AMPK_PRKAA1_ST	P15056	BRAF	Q13131	PRKAA1	S616	Q612E	612	Missense	distal	-4	no	63.466	64.879	EPSD	COSMIC	56.683	Up-regulation
CAMK_CAMKL_AMPK_PRKAA1_ST	P15056	BRAF	Q13131	PRKAA1	S616	I617T	617	Missense	proximal	1	no	63.466	64.002	EPSD	COSMIC	56.683	Up-regulation
CAMK_CAMKL_AMPK_PRKAA1_ST	P15056	BRAF	Q13131	PRKAA1	S616	W619R	619	Missense	distal	3	no	63.466	61.407	EPSD	COSMIC	56.683	Down-regulation
CAMK_CAMKL_AMPK_PRKAA1_ST	P15056	BRAF	Q13131	PRKAA1	S616	S614Y	614	Missense	proximal	-2	no	63.466	61.903	EPSD	COSMIC	56.683	Down-regulation
CAMK_CAMKL_AMPK_PRKAA1_ST	P15056	BRAF	Q13131	PRKAA1	S720	A718V	718	Missense	proximal	-2	no	61.501	63.533	EPSD	COSMIC	56.683	Up-regulation
CAMK_CAMKL_AMPK_PRKAA1_ST	P15056	BRAF	Q13131	PRKAA1	S720	R719P	719	Missense	proximal	-1	no	61.501	61.488	EPSD	COSMIC	56.683	Down-regulation
CAMK_CAMKL_AMPK_PRKAA1_ST	P15056	BRAF	Q13131	PRKAA1	S720	R719H	719	Missense	proximal	-1	no	61.501	61.520	EPSD	COSMIC	56.683	Up-regulation
CAMK_CAMKL_AMPK_PRKAA1_ST	P15056	BRAF	Q13131	PRKAA1	S720	E715K	715	Missense	distal	-5	no	61.501	58.853	EPSD	COSMIC	56.683	Down-regulation
CAMK_CAMKL_AMPK_PRKAA1_ST	P15056	BRAF	Q13131	PRKAA1	S720	S727T	727	Missense	distal	7	no	61.501	61.255	EPSD	COSMIC	56.683	Down-regulation
CAMK_CAMKL_AMPK_PRKAA1_ST	P15056	BRAF	Q13131	PRKAA1	S720	H725Q	725	Missense	distal	5	no	61.501	61.739	EPSD	COSMIC	56.683	Up-regulation
CAMK_CAMKL_AMPK_PRKAA1_ST	P15056	BRAF	Q13131	PRKAA1	S729	S732F	732	Missense	distal	3	no	73.936	72.728	PhosphoSitePlus	COSMIC	56.683	Down-regulation
CAMK_CAMKL_AMPK_PRKAA1_ST	P15056	BRAF	Q13131	PRKAA1	S729	A728D	728	Missense	proximal	-1	no	73.936	73.914	PhosphoSitePlus	COSMIC	56.683	Down-regulation
CAMK_CAMKL_AMPK_PRKAA1_ST	P15056	BRAF	Q13131	PRKAA1	S729	S727T	727	Missense	proximal	-2	no	73.936	71.253	PhosphoSitePlus	COSMIC	56.683	Down-regulation
CAMK_CAMKL_AMPK_PRKAA1_ST	P15056	BRAF	Q13131	PRKAA1	S729	H725Q	725	Missense	distal	-4	no	73.936	75.854	PhosphoSitePlus	COSMIC	56.683	Up-regulation
CAMK_CAMKL_AMPK_PRKAA1_ST	O14929	HAT1	Q13131	PRKAA1	S301	C299W	299	Missense	proximal	-2	no	61.163	65.935	EPSD	COSMIC	56.683	Up-regulation
CAMK_CAMKL_AMPK_PRKAA1_ST	Q12778	FOXO1	Q13131	PRKAA1	S22	R21L	21	Missense	proximal	-1	no	62.002	62.060	EPSD	COSMIC	56.683	Up-regulation
CAMK_CAMKL_AMPK_PRKAA1_ST	Q12778	FOXO1	Q13131	PRKAA1	S22	T24M	24	Missense	proximal	2	no	62.002	61.850	EPSD	COSMIC	56.683	Down-regulation
CAMK_CAMKL_AMPK_PRKAA1_ST	Q12778	FOXO1	Q13131	PRKAA1	S22	E15Q	15	Missense	distal	-7	no	62.002	61.969	EPSD	COSMIC	56.683	Down-regulation
CAMK_CAMKL_AMPK_PRKAA1_ST	Q12778	FOXO1	Q13131	PRKAA1	S22	R21S	21	Missense	proximal	-1	no	62.002	62.035	EPSD	COSMIC	56.683	Up-regulation
CAMK_CAMKL_AMPK_PRKAA1_ST	Q12778	FOXO1	Q13131	PRKAA1	S22	P28S	28	Missense	distal	6	no	62.002	62.017	EPSD	COSMIC	56.683	Up-regulation
CAMK_CAMKL_AMPK_PRKAA1_ST	Q12778	FOXO1	Q13131	PRKAA1	S22	P26L	26	Missense	distal	4	no	62.002	68.742	EPSD	COSMIC	56.683	Up-regulation
CAMK_CAMKL_AMPK_PRKAA1_ST	Q12778	FOXO1	Q13131	PRKAA1	S22	C23W	23	Missense	proximal	1	no	62.002	62.283	EPSD	COSMIC	56.683	Up-regulation
CAMK_CAMKL_AMPK_PRKAA1_ST	Q12778	FOXO1	Q13131	PRKAA1	S22	P26A	26	Missense	distal	4	no	62.002	64.211	EPSD	COSMIC	56.683	Up-regulation
CAMK_CAMKL_AMPK_PRKAA1_ST	Q12778	FOXO1	Q13131	PRKAA1	S22	R19P	19	Missense	distal	-3	no	62.002	53.142	EPSD	COSMIC	56.683	Loss
CAMK_CAMKL_AMPK_PRKAA1_ST	Q12778	FOXO1	Q13131	PRKAA1	S22	P16T	16	Missense	distal	-6	no	62.002	62.118	EPSD	COSMIC	56.683	Up-regulation
CAMK_CAMKL_AMPK_PRKAA1_ST	Q12778	FOXO1	Q13131	PRKAA1	S22	W25R	25	Missense	distal	3	no	62.002	59.944	EPSD	COSMIC	56.683	Down-regulation
CAMK_CAMKL_AMPK_PRKAA1_ST	Q12778	FOXO1	Q13131	PRKAA1	T24	R21L	21	Missense	distal	-3	no	60.529	50.562	EPSD	COSMIC	56.683	Loss
CAMK_CAMKL_AMPK_PRKAA1_ST	Q12778	FOXO1	Q13131	PRKAA1	T24	T24M	24	Missense	central	0	yes	60.529	0.000	EPSD	COSMIC	56.683	Loss
CAMK_CAMKL_AMPK_PRKAA1_ST	Q12778	FOXO1	Q13131	PRKAA1	T24	R21S	21	Missense	distal	-3	no	60.529	51.134	EPSD	COSMIC	56.683	Loss
CAMK_CAMKL_AMPK_PRKAA1_ST	Q12778	FOXO1	Q13131	PRKAA1	T24	P28S	28	Missense	distal	4	no	60.529	60.681	EPSD	COSMIC	56.683	Up-regulation
CAMK_CAMKL_AMPK_PRKAA1_ST	Q12778	FOXO1	Q13131	PRKAA1	T24	P26L	26	Missense	proximal	2	no	60.529	59.929	EPSD	COSMIC	56.683	Down-regulation
CAMK_CAMKL_AMPK_PRKAA1_ST	Q12778	FOXO1	Q13131	PRKAA1	T24	C23W	23	Missense	proximal	-1	no	60.529	60.469	EPSD	COSMIC	56.683	Down-regulation
CAMK_CAMKL_AMPK_PRKAA1_ST	Q12778	FOXO1	Q13131	PRKAA1	T24	P26A	26	Missense	proximal	2	no	60.529	59.785	EPSD	COSMIC	56.683	Down-regulation
CAMK_CAMKL_AMPK_PRKAA1_ST	Q12778	FOXO1	Q13131	PRKAA1	T24	R19P	19	Missense	distal	-5	no	60.529	56.965	EPSD	COSMIC	56.683	Down-regulation
CAMK_CAMKL_AMPK_PRKAA1_ST	Q12778	FOXO1	Q13131	PRKAA1	T24	W25R	25	Missense	proximal	1	no	60.529	59.923	EPSD	COSMIC	56.683	Down-regulation
CAMK_CAMKL_AMPK_PRKAA1_ST	Q12778	FOXO1	Q13131	PRKAA1	S164	W160C	160	Missense	distal	-4	no	54.236	67.210	EPSD	COSMIC	56.683	Gain
CAMK_CAMKL_AMPK_PRKAA1_ST	Q12778	FOXO1	Q13131	PRKAA1	S205	S203N	203	Missense	proximal	-2	no	57.171	56.511	EPSD	COSMIC	56.683	Loss
CAMK_CAMKL_AMPK_PRKAA1_ST	Q12778	FOXO1	Q13131	PRKAA1	S205	N204K	204	Missense	proximal	-1	no	57.171	57.105	EPSD	COSMIC	56.683	Down-regulation
CAMK_CAMKL_AMPK_PRKAA1_ST	Q12778	FOXO1	Q13131	PRKAA1	S205	S203R	203	Missense	proximal	-2	no	57.171	55.931	EPSD	COSMIC	56.683	Loss
CAMK_CAMKL_AMPK_PRKAA1_ST	Q12778	FOXO1	Q13131	PRKAA1	S205	D199H	199	Missense	distal	-6	no	57.171	53.723	EPSD	COSMIC	56.683	Loss
CAMK_CAMKL_AMPK_PRKAA1_ST	Q12778	FOXO1	Q13131	PRKAA1	S205	S205N	205	Missense	central	0	yes	57.171	0.000	EPSD	COSMIC	56.683	Loss
CAMK_CAMKL_AMPK_PRKAA1_ST	Q12778	FOXO1	Q13131	PRKAA1	S205	K210R	210	Missense	distal	5	no	57.171	57.230	EPSD	COSMIC	56.683	Up-regulation
CAMK_CAMKL_AMPK_PRKAA1_ST	Q12778	FOXO1	Q13131	PRKAA1	S206	S203R	203	Missense	distal	-3	no	49.498	58.894	EPSD	COSMIC	56.683	Gain
CAMK_CAMKL_AMPK_PRKAA1_ST	Q12778	FOXO1	Q13131	PRKAA1	S218	S218F	218	Missense	central	0	yes	57.131	0.000	EPSD	COSMIC	56.683	Loss
CAMK_CAMKL_AMPK_PRKAA1_ST	Q12778	FOXO1	Q13131	PRKAA1	S218	N216K	216	Missense	proximal	-2	no	57.131	57.930	EPSD	COSMIC	56.683	Up-regulation
CAMK_CAMKL_AMPK_PRKAA1_ST	Q12778	FOXO1	Q13131	PRKAA1	S290	S287N	287	Missense	distal	-3	no	55.036	58.495	EPSD	COSMIC	56.683	Gain
CAMK_CAMKL_AMPK_PRKAA1_ST	Q12778	FOXO1	Q13131	PRKAA1	T317	P315F	315	Missense	proximal	-2	no	62.020	59.273	EPSD	COSMIC	56.683	Down-regulation
CAMK_CAMKL_AMPK_PRKAA1_ST	Q12778	FOXO1	Q13131	PRKAA1	T317	W310C	310	Missense	distal	-7	no	62.020	58.829	EPSD	COSMIC	56.683	Down-regulation
CAMK_CAMKL_AMPK_PRKAA1_ST	Q12778	FOXO1	Q13131	PRKAA1	S319	P315F	315	Missense	distal	-4	no	64.829	64.226	EPSD	COSMIC	56.683	Down-regulation
CAMK_CAMKL_AMPK_PRKAA1_ST	Q12778	FOXO1	Q13131	PRKAA1	S345	S345Y	345	Missense	central	0	yes	57.965	0.000	EPSD	COSMIC;CCLE	56.683	Loss
CAMK_CAMKL_AMPK_PRKAA1_ST	Q12778	FOXO1	Q13131	PRKAA1	S345	V343E	343	Missense	proximal	-2	no	57.965	56.820	EPSD	COSMIC	56.683	Down-regulation
CAMK_CAMKL_AMPK_PRKAA1_ST	Q12778	FOXO1	Q13131	PRKAA1	S345	Y348F	348	Missense	distal	3	no	57.965	55.837	EPSD	COSMIC	56.683	Loss
CAMK_CAMKL_AMPK_PRKAA1_ST	Q12778	FOXO1	Q13131	PRKAA1	S345	V343A	343	Missense	proximal	-2	no	57.965	55.932	EPSD	COSMIC	56.683	Loss
CAMK_CAMKL_AMPK_PRKAA1_ST	Q12778	FOXO1	Q13131	PRKAA1	T649	S644I	644	Missense	distal	-5	no	56.935	61.695	PhosphoSitePlus	COSMIC	56.683	Up-regulation
CAMK_CAMKL_AMPK_PRKAA1_ST	P43405	SYK	Q13131	PRKAA1	S93	V100F	100	Missense	distal	7	no	55.925	56.947	EPSD	COSMIC	56.683	Gain
CAMK_CAMKL_AMPK_PRKAA1_ST	P43405	SYK	Q13131	PRKAA1	S93	Q94R	94	Missense	proximal	1	no	55.925	56.805	EPSD	COSMIC	56.683	Gain
CAMK_CAMKL_AMPK_PRKAA1_ST	P43405	SYK	Q13131	PRKAA1	S178	E177K	177	Missense	proximal	-1	no	65.506	65.481	PhosphoSitePlus	COSMIC	56.683	Down-regulation
CAMK_CAMKL_AMPK_PRKAA1_ST	P43405	SYK	Q13131	PRKAA1	S295	S297F	297	Missense	proximal	2	no	60.446	60.153	EPSD	COSMIC	56.683	Down-regulation
CAMK_CAMKL_AMPK_PRKAA1_ST	P43405	SYK	Q13131	PRKAA1	S295	I293L	293	Missense	proximal	-2	no	60.446	59.897	EPSD	COSMIC	56.683	Down-regulation
CAMK_CAMKL_AMPK_PRKAA1_ST	P43405	SYK	Q13131	PRKAA1	S295	S291P	291	Missense	distal	-4	no	60.446	59.203	EPSD	COSMIC	56.683	Down-regulation
CAMK_CAMKL_AMPK_PRKAA1_ST	P43405	SYK	Q13131	PRKAA1	S297	S297F	297	Missense	central	0	yes	61.680	0.000	EPSD	COSMIC	56.683	Loss
CAMK_CAMKL_AMPK_PRKAA1_ST	P43405	SYK	Q13131	PRKAA1	S297	I293L	293	Missense	distal	-4	no	61.680	62.983	EPSD	COSMIC	56.683	Up-regulation
CAMK_CAMKL_AMPK_PRKAA1_ST	P43405	SYK	Q13131	PRKAA1	S297	R304I	304	Missense	distal	7	no	61.680	61.174	EPSD	COSMIC	56.683	Down-regulation
CAMK_CAMKL_AMPK_PRKAA1_ST	P43405	SYK	Q13131	PRKAA1	S297	S291P	291	Missense	distal	-6	no	61.680	62.030	EPSD	COSMIC	56.683	Up-regulation
CAMK_CAMKL_AMPK_PRKAA1_ST	P43405	SYK	Q13131	PRKAA1	S307	A309S	309	Missense	proximal	2	no	57.039	57.239	EPSD	COSMIC	56.683	Up-regulation
CAMK_CAMKL_AMPK_PRKAA1_ST	P43405	SYK	Q13131	PRKAA1	S307	A309E	309	Missense	proximal	2	no	57.039	57.842	EPSD	COSMIC	56.683	Up-regulation
CAMK_CAMKL_AMPK_PRKAA1_ST	P43405	SYK	Q13131	PRKAA1	S307	G311E	311	Missense	distal	4	no	57.039	53.481	EPSD	COSMIC	56.683	Loss
CAMK_CAMKL_AMPK_PRKAA1_ST	P43405	SYK	Q13131	PRKAA1	S307	S306F	306	Missense	proximal	-1	no	57.039	56.992	EPSD	COSMIC	56.683	Down-regulation
CAMK_CAMKL_AMPK_PRKAA1_ST	P43405	SYK	Q13131	PRKAA1	S307	P308T	308	Missense	proximal	1	no	57.039	56.629	EPSD	COSMIC	56.683	Loss
CAMK_CAMKL_AMPK_PRKAA1_ST	P43405	SYK	Q13131	PRKAA1	S307	S307F	307	Missense	central	0	yes	57.039	0.000	EPSD	COSMIC	56.683	Loss
CAMK_CAMKL_AMPK_PRKAA1_ST	P43405	SYK	Q13131	PRKAA1	S307	R313W	313	Missense	distal	6	no	57.039	56.548	EPSD	COSMIC	56.683	Loss
CAMK_CAMKL_AMPK_PRKAA1_ST	P43405	SYK	Q13131	PRKAA1	S307	R304I	304	Missense	distal	-3	no	57.039	43.641	EPSD	COSMIC	56.683	Loss
CAMK_CAMKL_AMPK_PRKAA1_ST	P43405	SYK	Q13131	PRKAA1	S307	Q310L	310	Missense	distal	3	no	57.039	54.314	EPSD	COSMIC	56.683	Loss
CAMK_CAMKL_AMPK_PRKAA1_ST	P43405	SYK	Q13131	PRKAA1	S307	P308H	308	Missense	proximal	1	no	57.039	59.682	EPSD	COSMIC	56.683	Up-regulation
CAMK_CAMKL_AMPK_PRKAA1_ST	P43405	SYK	Q13131	PRKAA1	S307	R313L	313	Missense	distal	6	no	57.039	57.279	EPSD	COSMIC	56.683	Up-regulation
CAMK_CAMKL_AMPK_PRKAA1_ST	P43405	SYK	Q13131	PRKAA1	S316	A309S	309	Missense	distal	-7	no	59.006	61.708	EPSD	COSMIC	56.683	Up-regulation
CAMK_CAMKL_AMPK_PRKAA1_ST	P43405	SYK	Q13131	PRKAA1	S316	A309E	309	Missense	distal	-7	no	59.006	60.922	EPSD	COSMIC	56.683	Up-regulation
CAMK_CAMKL_AMPK_PRKAA1_ST	P43405	SYK	Q13131	PRKAA1	S316	G311E	311	Missense	distal	-5	no	59.006	61.572	EPSD	COSMIC	56.683	Up-regulation
CAMK_CAMKL_AMPK_PRKAA1_ST	P43405	SYK	Q13131	PRKAA1	S316	P322S	322	Missense	distal	6	no	59.006	59.021	EPSD	COSMIC	56.683	Up-regulation
CAMK_CAMKL_AMPK_PRKAA1_ST	P43405	SYK	Q13131	PRKAA1	S316	R313W	313	Missense	distal	-3	no	59.006	-33.994	EPSD	COSMIC	56.683	Loss
CAMK_CAMKL_AMPK_PRKAA1_ST	P43405	SYK	Q13131	PRKAA1	S316	Q310L	310	Missense	distal	-6	no	59.006	58.487	EPSD	COSMIC	56.683	Down-regulation
CAMK_CAMKL_AMPK_PRKAA1_ST	P43405	SYK	Q13131	PRKAA1	S316	P322L	322	Missense	distal	6	no	59.006	59.154	EPSD	COSMIC	56.683	Up-regulation
CAMK_CAMKL_AMPK_PRKAA1_ST	P43405	SYK	Q13131	PRKAA1	S316	R313L	313	Missense	distal	-3	no	59.006	49.039	EPSD	COSMIC	56.683	Loss
CAMK_CAMKL_AMPK_PRKAA1_ST	P43405	SYK	Q13131	PRKAA1	S316	S316N	316	Missense	central	0	yes	59.006	0.000	EPSD	COSMIC	56.683	Loss
CAMK_CAMKL_AMPK_PRKAA1_ST	P43405	SYK	Q13131	PRKAA1	S316	S316C	316	Missense	central	0	yes	59.006	0.000	EPSD	COSMIC	56.683	Loss
CAMK_CAMKL_AMPK_PRKAA1_ST	Q9NR19	ACSS2	Q13131	PRKAA1	S43	Q45H	45	Missense	proximal	2	no	61.788	62.560	EPSD	COSMIC	56.683	Up-regulation
CAMK_CAMKL_AMPK_PRKAA1_ST	Q9NR19	ACSS2	Q13131	PRKAA1	S659	R665L	665	Missense	distal	6	no	60.751	60.991	PhosphoSitePlus	COSMIC	56.683	Up-regulation
CAMK_CAMKL_AMPK_PRKAA1_ST	Q9NR19	ACSS2	Q13131	PRKAA1	S659	R664M	664	Missense	distal	5	no	60.751	60.571	PhosphoSitePlus	COSMIC	56.683	Down-regulation
CAMK_CAMKL_AMPK_PRKAA1_ST	Q9NR19	ACSS2	Q13131	PRKAA1	S659	R658C	658	Missense	proximal	-1	no	60.751	60.897	PhosphoSitePlus	COSMIC;GDSC;CCLE	56.683	Up-regulation
CAMK_CAMKL_AMPK_PRKAA1_ST	Q9NR19	ACSS2	Q13131	PRKAA1	S659	K656N	656	Missense	distal	-3	no	60.751	59.456	PhosphoSitePlus	COSMIC	56.683	Down-regulation
CAMK_CAMKL_AMPK_PRKAA1_ST	O00763	ACACB	Q13131	PRKAA1	S37	P43Q	43	Missense	distal	6	no	68.031	68.369	EPSD	COSMIC	56.683	Up-regulation
CAMK_CAMKL_AMPK_PRKAA1_ST	O00763	ACACB	Q13131	PRKAA1	S192	L199M	199	Missense	distal	7	no	59.804	57.800	EPSD	COSMIC	56.683	Down-regulation
CAMK_CAMKL_AMPK_PRKAA1_ST	O00763	ACACB	Q13131	PRKAA1	T216	E211G	211	Missense	distal	-5	no	60.087	57.521	EPSD	COSMIC	56.683	Down-regulation
CAMK_CAMKL_AMPK_PRKAA1_ST	O00763	ACACB	Q13131	PRKAA1	T216	A210T	210	Missense	distal	-6	no	60.087	59.884	EPSD	COSMIC	56.683	Down-regulation
CAMK_CAMKL_AMPK_PRKAA1_ST	O00763	ACACB	Q13131	PRKAA1	T216	A210S	210	Missense	distal	-6	no	60.087	59.418	EPSD	COSMIC	56.683	Down-regulation
CAMK_CAMKL_AMPK_PRKAA1_ST	O00763	ACACB	Q13131	PRKAA1	T216	R213G	213	Missense	distal	-3	no	60.087	51.052	EPSD	COSMIC	56.683	Loss
CAMK_CAMKL_AMPK_PRKAA1_ST	O00763	ACACB	Q13131	PRKAA1	T243	V244M	244	Missense	proximal	1	no	58.555	60.734	EPSD	COSMIC	56.683	Up-regulation
CAMK_CAMKL_AMPK_PRKAA1_ST	O00763	ACACB	Q13131	PRKAA1	T243	L238P	238	Missense	distal	-5	no	58.555	53.815	EPSD	COSMIC	56.683	Loss
CAMK_CAMKL_AMPK_PRKAA1_ST	O00763	ACACB	Q13131	PRKAA1	T243	V244G	244	Missense	proximal	1	no	58.555	59.279	EPSD	COSMIC	56.683	Up-regulation
CAMK_CAMKL_AMPK_PRKAA1_ST	O00763	ACACB	Q13131	PRKAA1	T243	A245V	245	Missense	proximal	2	no	58.555	59.701	EPSD	COSMIC	56.683	Up-regulation
CAMK_CAMKL_AMPK_PRKAA1_ST	O00763	ACACB	Q13131	PRKAA1	S469	A470V	470	Missense	proximal	1	no	65.316	66.775	EPSD	COSMIC	56.683	Up-regulation
CAMK_CAMKL_AMPK_PRKAA1_ST	O00763	ACACB	Q13131	PRKAA1	S469	P474S	474	Missense	distal	5	no	65.316	65.277	EPSD	COSMIC	56.683	Down-regulation
CAMK_CAMKL_AMPK_PRKAA1_ST	O00763	ACACB	Q13131	PRKAA1	S1340	V1337M	1337	Missense	distal	-3	no	59.875	55.407	EPSD	COSMIC;CCLE	56.683	Loss
CAMK_CAMKL_AMPK_PRKAA1_ST	O00763	ACACB	Q13131	PRKAA1	S1340	D1345E	1345	Missense	distal	5	no	59.875	59.722	EPSD	COSMIC	56.683	Down-regulation
CAMK_CAMKL_AMPK_PRKAA1_ST	O00763	ACACB	Q13131	PRKAA1	S1557	S1557F	1557	Missense	central	0	yes	67.527	0.000	EPSD	COSMIC	56.683	Loss
CAMK_CAMKL_AMPK_PRKAA1_ST	O00763	ACACB	Q13131	PRKAA1	S1557	E1564K	1564	Missense	distal	7	no	67.527	66.831	EPSD	COSMIC	56.683	Down-regulation
CAMK_CAMKL_AMPK_PRKAA1_ST	O00763	ACACB	Q13131	PRKAA1	S1557	Q1562H	1562	Missense	distal	5	no	67.527	67.289	EPSD	COSMIC	56.683	Down-regulation
CAMK_CAMKL_AMPK_PRKAA1_ST	O00763	ACACB	Q13131	PRKAA1	S1557	T1553K	1553	Missense	distal	-4	no	67.527	66.667	EPSD	COSMIC	56.683	Down-regulation
CAMK_CAMKL_AMPK_PRKAA1_ST	O00763	ACACB	Q13131	PRKAA1	S1620	R1626C	1626	Missense	distal	6	no	63.001	63.332	EPSD	COSMIC	56.683	Up-regulation
CAMK_CAMKL_AMPK_PRKAA1_ST	O00763	ACACB	Q13131	PRKAA1	S1620	R1621W	1621	Missense	proximal	1	no	63.001	63.607	EPSD	COSMIC;CCLE	56.683	Up-regulation
CAMK_CAMKL_AMPK_PRKAA1_ST	O00763	ACACB	Q13131	PRKAA1	S1620	V1615A	1615	Missense	distal	-5	no	63.001	64.194	EPSD	COSMIC	56.683	Up-regulation
CAMK_CAMKL_AMPK_PRKAA1_ST	O00763	ACACB	Q13131	PRKAA1	S1620	R1617H	1617	Missense	distal	-3	no	63.001	55.145	EPSD	COSMIC	56.683	Loss
CAMK_CAMKL_AMPK_PRKAA1_ST	O00763	ACACB	Q13131	PRKAA1	S1620	M1614L	1614	Missense	distal	-6	no	63.001	64.152	EPSD	COSMIC	56.683	Up-regulation
CAMK_CAMKL_AMPK_PRKAA1_ST	O00763	ACACB	Q13131	PRKAA1	S1620	R1626H	1626	Missense	distal	6	no	63.001	63.107	EPSD	COSMIC	56.683	Up-regulation
CAMK_CAMKL_AMPK_PRKAA1_ST	O00763	ACACB	Q13131	PRKAA1	T1641	R1637C	1637	Missense	distal	-4	no	54.868	59.179	EPSD	COSMIC	56.683	Gain
CAMK_CAMKL_AMPK_PRKAA1_ST	O00763	ACACB	Q13131	PRKAA1	S1877	V1878I	1878	Missense	proximal	1	no	57.528	56.085	EPSD	COSMIC	56.683	Loss
CAMK_CAMKL_AMPK_PRKAA1_ST	O00763	ACACB	Q13131	PRKAA1	S1877	E1884K	1884	Missense	distal	7	no	57.528	56.832	EPSD	COSMIC	56.683	Down-regulation
CAMK_CAMKL_AMPK_PRKAA1_ST	Q13501	SQSTM1	Q13131	PRKAA1	S24	R22W	22	Missense	proximal	-2	no	59.560	57.221	EPSD	COSMIC	56.683	Down-regulation
CAMK_CAMKL_AMPK_PRKAA1_ST	Q13501	SQSTM1	Q13131	PRKAA1	S49	V51L	51	Missense	proximal	2	no	58.303	57.301	EPSD	COSMIC	56.683	Down-regulation
CAMK_CAMKL_AMPK_PRKAA1_ST	Q13501	SQSTM1	Q13131	PRKAA1	S49	C44G	44	Missense	distal	-5	no	58.303	56.648	EPSD	COSMIC	56.683	Loss
CAMK_CAMKL_AMPK_PRKAA1_ST	Q13501	SQSTM1	Q13131	PRKAA1	S49	V51A	51	Missense	proximal	2	no	58.303	57.157	EPSD	COSMIC	56.683	Down-regulation
CAMK_CAMKL_AMPK_PRKAA1_ST	Q13501	SQSTM1	Q13131	PRKAA1	T164	A167T	167	Missense	distal	3	no	55.073	57.988	EPSD	COSMIC	56.683	Gain
CAMK_CAMKL_AMPK_PRKAA1_ST	Q13501	SQSTM1	Q13131	PRKAA1	T164	G158D	158	Missense	distal	-6	no	55.073	57.952	EPSD	COSMIC	56.683	Gain
CAMK_CAMKL_AMPK_PRKAA1_ST	Q13501	SQSTM1	Q13131	PRKAA1	S180	R183C	183	Missense	distal	3	no	57.331	56.151	EPSD	COSMIC	56.683	Loss
CAMK_CAMKL_AMPK_PRKAA1_ST	Q13501	SQSTM1	Q13131	PRKAA1	S233	S226F	226	Missense	distal	-7	no	58.665	56.072	EPSD	COSMIC	56.683	Loss
CAMK_CAMKL_AMPK_PRKAA1_ST	Q13501	SQSTM1	Q13131	PRKAA1	S233	K238E	238	Missense	distal	5	no	58.665	58.644	EPSD	COSMIC	56.683	Down-regulation
CAMK_CAMKL_AMPK_PRKAA1_ST	Q13501	SQSTM1	Q13131	PRKAA1	S284	C289Y	289	Missense	distal	5	no	63.501	63.553	EPSD	COSMIC;GDSC;CCLE	56.683	Up-regulation
CAMK_CAMKL_AMPK_PRKAA1_ST	Q13501	SQSTM1	Q13131	PRKAA1	S294	C289Y	289	Missense	distal	-5	no	64.675	62.168	PhosphoSitePlus	COSMIC;GDSC;CCLE	56.683	Down-regulation
CAMK_CAMKL_AMPK_PRKAA1_ST	Q13501	SQSTM1	Q13131	PRKAA1	S349	T350I	350	Missense	proximal	1	no	61.532	60.996	EPSD	COSMIC	56.683	Down-regulation
CMGC_CDK_CRK7_CDK12_ST	P24928	POLR2A	Q9NYV4	CDK12	S27	R33Q	33	Missense	distal	6	no	3.928	3.933	EPSD	COSMIC;CCLE	0.929	Up-regulation
CMGC_CDK_CRK7_CDK12_ST	P24928	POLR2A	Q9NYV4	CDK12	S27	G24A	24	Missense	distal	-3	no	3.928	3.936	EPSD	COSMIC	0.929	Up-regulation
CMGC_CDK_CRK7_CDK12_ST	P24928	POLR2A	Q9NYV4	CDK12	S217	E219V	219	Missense	proximal	2	no	4.639	4.527	EPSD	COSMIC	0.929	Down-regulation
CMGC_CDK_CRK7_CDK12_ST	P24928	POLR2A	Q9NYV4	CDK12	T368	T365I	365	Missense	distal	-3	no	4.124	4.084	EPSD	COSMIC	0.929	Down-regulation
CMGC_CDK_CRK7_CDK12_ST	P24928	POLR2A	Q9NYV4	CDK12	T368	R364C	364	Missense	distal	-4	no	4.124	4.046	EPSD	COSMIC	0.929	Down-regulation
CAMK_CAMK1_CAMK4_ST	Q9UQL6	HDAC5	Q16566	CAMK4	S16	L20M	20	Missense	distal	4	no	10.938	10.630	EPSD	COSMIC	9.847	Down-regulation
CAMK_CAMK1_CAMK4_ST	Q9UQL6	HDAC5	Q16566	CAMK4	S16	R13W	13	Missense	distal	-3	no	10.938	4.285	EPSD	COSMIC	9.847	Loss
CAMK_CAMK1_CAMK4_ST	Q9UQL6	HDAC5	Q16566	CAMK4	S16	L17F	17	Missense	proximal	1	no	10.938	10.808	EPSD	COSMIC	9.847	Down-regulation
CAMK_CAMK1_CAMK4_ST	Q9UQL6	HDAC5	Q16566	CAMK4	S16	E18Q	18	Missense	proximal	2	no	10.938	10.934	EPSD	COSMIC	9.847	Down-regulation
CAMK_CAMK1_CAMK4_ST	Q9UQL6	HDAC5	Q16566	CAMK4	S16	G12R	12	Missense	distal	-4	no	10.938	11.929	EPSD	COSMIC	9.847	Up-regulation
CAMK_CAMK1_CAMK4_ST	Q9UQL6	HDAC5	Q16566	CAMK4	S229	P236S	236	Missense	distal	7	no	7.429	11.005	EPSD	COSMIC	9.847	Gain
CAMK_CAMK1_CAMK4_ST	Q9UQL6	HDAC5	Q16566	CAMK4	S259	R255C	255	Missense	distal	-4	no	16.155	15.169	EPSD;PhosphoSitePlus	COSMIC	9.847	Down-regulation
CAMK_CAMK1_CAMK4_ST	Q9UQL6	HDAC5	Q16566	CAMK4	S259	R266C	266	Missense	distal	7	no	16.155	14.170	EPSD;PhosphoSitePlus	COSMIC	9.847	Down-regulation
CAMK_CAMK1_CAMK4_ST	Q9UQL6	HDAC5	Q16566	CAMK4	S259	R266H	266	Missense	distal	7	no	16.155	13.861	EPSD;PhosphoSitePlus	COSMIC	9.847	Down-regulation
CAMK_CAMK1_CAMK4_ST	Q9UQL6	HDAC5	Q16566	CAMK4	S279	R284C	284	Missense	distal	5	no	14.986	14.563	EPSD	COSMIC	9.847	Down-regulation
CAMK_CAMK1_CAMK4_ST	Q9UQL6	HDAC5	Q16566	CAMK4	S279	S279N	279	Missense	central	0	yes	14.986	0.000	EPSD	COSMIC	9.847	Loss
CAMK_CAMK1_CAMK4_ST	Q9UQL6	HDAC5	Q16566	CAMK4	S279	R284S	284	Missense	distal	5	no	14.986	14.947	EPSD	COSMIC	9.847	Down-regulation
CAMK_CAMK1_CAMK4_ST	Q9UQL6	HDAC5	Q16566	CAMK4	T479	R476H	476	Missense	distal	-3	no	13.294	5.568	EPSD	COSMIC	9.847	Loss
CAMK_CAMK1_CAMK4_ST	Q9UQL6	HDAC5	Q16566	CAMK4	T479	T473M	473	Missense	distal	-6	no	13.294	13.480	EPSD	COSMIC	9.847	Up-regulation
CAMK_CAMK1_CAMK4_ST	Q9UQL6	HDAC5	Q16566	CAMK4	T479	G474C	474	Missense	distal	-5	no	13.294	12.867	EPSD	COSMIC	9.847	Down-regulation
CAMK_CAMK1_CAMK4_ST	Q9UQL6	HDAC5	Q16566	CAMK4	T479	R476C	476	Missense	distal	-3	no	13.294	7.223	EPSD	COSMIC	9.847	Loss
CAMK_CAMK1_CAMK4_ST	Q9UQL6	HDAC5	Q16566	CAMK4	T479	T483M	483	Missense	distal	4	no	13.294	13.711	EPSD	COSMIC	9.847	Up-regulation
CAMK_CAMK1_CAMK4_ST	Q9UQL6	HDAC5	Q16566	CAMK4	T479	A478V	478	Missense	proximal	-1	no	13.294	12.078	EPSD	COSMIC;CCLE	9.847	Down-regulation
CAMK_CAMK1_CAMK4_ST	Q9UQL6	HDAC5	Q16566	CAMK4	T479	R482W	482	Missense	distal	3	no	13.294	13.342	EPSD	COSMIC	9.847	Up-regulation
CAMK_CAMK1_CAMK4_ST	Q9UQL6	HDAC5	Q16566	CAMK4	S498	R491W	491	Missense	distal	-7	no	16.621	14.588	PhosphoSitePlus;EPSD	COSMIC	9.847	Down-regulation
CAMK_CAMK1_CAMK4_ST	Q9UQL6	HDAC5	Q16566	CAMK4	T546	E553K	553	Missense	distal	7	no	9.485	10.017	EPSD	COSMIC	9.847	Gain
CAMK_CAMK1_CAMK4_ST	Q9UQL6	HDAC5	Q16566	CAMK4	S661	R658L	658	Missense	distal	-3	no	13.300	5.437	EPSD	COSMIC	9.847	Loss
CAMK_CAMK1_CAMK4_ST	Q9UQL6	HDAC5	Q16566	CAMK4	S661	R658H	658	Missense	distal	-3	no	13.300	5.574	EPSD	COSMIC	9.847	Loss
CAMK_CAMK1_CAMK4_ST	Q9UQL6	HDAC5	Q16566	CAMK4	S661	T659S	659	Missense	proximal	-2	no	13.300	14.143	EPSD	COSMIC	9.847	Up-regulation
CAMK_CAMK1_CAMK4_ST	Q9UQL6	HDAC5	Q16566	CAMK4	S662	T659S	659	Missense	distal	-3	no	8.197	10.150	EPSD	COSMIC	9.847	Gain
CAMK_CAMK1_CAMK4_ST	Q9UQL6	HDAC5	Q16566	CAMK4	S713	R717H	717	Missense	distal	4	no	10.541	10.228	EPSD	COSMIC	9.847	Down-regulation
CAMK_CAMK1_CAMK4_ST	Q9UQL6	HDAC5	Q16566	CAMK4	S713	R710Q	710	Missense	distal	-3	no	10.541	5.858	EPSD	COSMIC	9.847	Loss
CAMK_CAMK1_CAMK4_ST	Q9UQL6	HDAC5	Q16566	CAMK4	S713	Q719H	719	Missense	distal	6	no	10.541	10.458	EPSD	COSMIC	9.847	Down-regulation
CAMK_CAMK1_CAMK4_ST	Q9UQL6	HDAC5	Q16566	CAMK4	S713	S713G	713	Missense	central	0	yes	10.541	0.000	EPSD	COSMIC	9.847	Loss
CAMK_CAMK1_CAMK4_ST	Q9UQL6	HDAC5	Q16566	CAMK4	S1108	E1106K	1106	Missense	proximal	-2	no	10.348	11.728	EPSD	COSMIC	9.847	Up-regulation
CAMK_CAMK1_CAMK4_ST	Q9UQL6	HDAC5	Q16566	CAMK4	S1108	A1104T	1104	Missense	distal	-4	no	10.348	9.375	EPSD	COSMIC;CCLE	9.847	Loss
CAMK_CAMK1_CAMK4_ST	P16220	CREB1	Q16566	CAMK4	S98	S103N	103	Missense	distal	5	no	14.403	14.366	EPSD	COSMIC	9.847	Down-regulation
CAMK_CAMK1_CAMK4_ST	P16220	CREB1	Q16566	CAMK4	S98	R95I	95	Missense	distal	-3	no	14.403	6.901	EPSD	COSMIC	9.847	Loss
CAMK_CAMK1_CAMK4_ST	P16220	CREB1	Q16566	CAMK4	S98	I102M	102	Missense	distal	4	no	14.403	14.277	EPSD	COSMIC	9.847	Down-regulation
CAMK_CAMK1_CAMK4_ST	P16220	CREB1	Q16566	CAMK4	S114	S117N	117	Missense	distal	3	no	10.753	10.560	EPSD	COSMIC	9.847	Down-regulation
CAMK_CAMK1_CAMK4_ST	P16220	CREB1	Q16566	CAMK4	S114	V118L	118	Missense	distal	4	no	10.753	11.269	EPSD	COSMIC	9.847	Up-regulation
CAMK_CAMK1_CAMK4_ST	P16220	CREB1	Q16566	CAMK4	S114	E109K	109	Missense	distal	-5	no	10.753	11.355	EPSD	COSMIC	9.847	Up-regulation
CAMK_CAMK1_CAMK4_ST	P16220	CREB1	Q16566	CAMK4	S114	V118I	118	Missense	distal	4	no	10.753	11.086	EPSD	COSMIC	9.847	Up-regulation
CAMK_CAMK1_CAMK4_ST	P16220	CREB1	Q16566	CAMK4	S121	L128R	128	Missense	distal	7	no	8.992	10.298	EPSD	COSMIC	9.847	Gain
CAMK_CAMK1_CAMK4_ST	P16220	CREB1	Q16566	CAMK4	S133	L128R	128	Missense	distal	-5	no	14.892	13.113	PhosphoSitePlus	COSMIC	9.847	Down-regulation
CAMK_CAMK1_CAMK4_ST	P16220	CREB1	Q16566	CAMK4	S270	A269T	269	Missense	proximal	-1	no	10.294	9.431	EPSD	COSMIC	9.847	Loss
CAMK_CAMK1_CAMK4_ST	P16220	CREB1	Q16566	CAMK4	S270	P264T	264	Missense	distal	-6	no	10.294	10.197	EPSD	COSMIC;GDSC;CCLE	9.847	Down-regulation
CAMK_CAMK1_CAMK4_ST	P14866	HNRNPL	Q16566	CAMK4	S29	A36V	36	Missense	distal	7	no	13.658	12.362	EPSD	COSMIC	9.847	Down-regulation
CAMK_CAMK1_CAMK4_ST	P14866	HNRNPL	Q16566	CAMK4	T63	P58L	58	Missense	distal	-5	no	8.649	10.182	EPSD	COSMIC	9.847	Gain
CAMK_CAMK1_CAMK4_ST	P14866	HNRNPL	Q16566	CAMK4	S180	R181G	181	Missense	proximal	1	no	10.888	10.781	EPSD	COSMIC	9.847	Down-regulation
CAMK_CAMK1_CAMK4_ST	P14866	HNRNPL	Q16566	CAMK4	S180	R181C	181	Missense	proximal	1	no	10.888	10.767	EPSD	COSMIC	9.847	Down-regulation
CAMK_CAMK1_CAMK4_ST	P14866	HNRNPL	Q16566	CAMK4	S180	Y173C	173	Missense	distal	-7	no	10.888	11.368	EPSD	COSMIC	9.847	Up-regulation
CAMK_CAMK1_CAMK4_ST	P14866	HNRNPL	Q16566	CAMK4	S188	R181G	181	Missense	distal	-7	no	10.614	7.975	EPSD	COSMIC	9.847	Loss
CAMK_CAMK1_CAMK4_ST	P14866	HNRNPL	Q16566	CAMK4	S188	R181C	181	Missense	distal	-7	no	10.614	8.694	EPSD	COSMIC	9.847	Loss
CAMK_CAMK1_CAMK4_ST	P14866	HNRNPL	Q16566	CAMK4	S250	N252S	252	Missense	proximal	2	no	10.645	10.635	EPSD	COSMIC	9.847	Down-regulation
CAMK_CAMK1_CAMK4_ST	P14866	HNRNPL	Q16566	CAMK4	T487	T487I	487	Missense	central	0	yes	12.576	0.000	EPSD	COSMIC	9.847	Loss
CAMK_CAMK1_CAMK4_ST	P14866	HNRNPL	Q16566	CAMK4	S530	S536L	536	Missense	distal	6	no	10.781	10.595	EPSD	COSMIC	9.847	Down-regulation
CAMK_CAMK1_CAMK4_ST	P14866	HNRNPL	Q16566	CAMK4	S530	R528Q	528	Missense	proximal	-2	no	10.781	9.427	EPSD	COSMIC	9.847	Loss
CAMK_CAMK1_CAMK4_ST	P14866	HNRNPL	Q16566	CAMK4	S531	S536L	536	Missense	distal	5	no	12.818	12.674	EPSD	COSMIC	9.847	Down-regulation
CAMK_CAMK1_CAMK4_ST	P14866	HNRNPL	Q16566	CAMK4	S531	R528Q	528	Missense	distal	-3	no	12.818	8.135	EPSD	COSMIC	9.847	Loss
CAMK_CAMK1_CAMK4_ST	P14866	HNRNPL	Q16566	CAMK4	S536	E540G	540	Missense	distal	4	no	15.370	15.329	EPSD	COSMIC	9.847	Down-regulation
CAMK_CAMK1_CAMK4_ST	P14866	HNRNPL	Q16566	CAMK4	S536	R541C	541	Missense	distal	5	no	15.370	14.947	EPSD	COSMIC	9.847	Down-regulation
CAMK_CAMK1_CAMK4_ST	P14866	HNRNPL	Q16566	CAMK4	S536	E540K	540	Missense	distal	4	no	15.370	15.414	EPSD	COSMIC	9.847	Up-regulation
CAMK_CAMK1_CAMK4_ST	P14866	HNRNPL	Q16566	CAMK4	S536	S536L	536	Missense	central	0	yes	15.370	0.000	EPSD	COSMIC	9.847	Loss
CAMK_CAMK1_CAMK4_ST	P14866	HNRNPL	Q16566	CAMK4	S539	E540G	540	Missense	proximal	1	no	10.787	10.737	EPSD	COSMIC	9.847	Down-regulation
CAMK_CAMK1_CAMK4_ST	P14866	HNRNPL	Q16566	CAMK4	S539	R541C	541	Missense	proximal	2	no	10.787	10.829	EPSD	COSMIC	9.847	Up-regulation
CAMK_CAMK1_CAMK4_ST	P14866	HNRNPL	Q16566	CAMK4	S539	E540K	540	Missense	proximal	1	no	10.787	10.788	EPSD	COSMIC	9.847	Up-regulation
CAMK_CAMK1_CAMK4_ST	P14866	HNRNPL	Q16566	CAMK4	S539	S536L	536	Missense	distal	-3	no	10.787	7.192	EPSD	COSMIC	9.847	Loss
CAMK_CAMK1_CAMK4_ST	P14866	HNRNPL	Q16566	CAMK4	S543	E540G	540	Missense	distal	-3	no	10.875	9.682	EPSD	COSMIC	9.847	Loss
CAMK_CAMK1_CAMK4_ST	P14866	HNRNPL	Q16566	CAMK4	S543	R541C	541	Missense	proximal	-2	no	10.875	8.905	EPSD	COSMIC	9.847	Loss
CAMK_CAMK1_CAMK4_ST	P14866	HNRNPL	Q16566	CAMK4	S543	E540K	540	Missense	distal	-3	no	10.875	15.587	EPSD	COSMIC	9.847	Up-regulation
CAMK_CAMK1_CAMK4_ST	P14866	HNRNPL	Q16566	CAMK4	S543	S536L	536	Missense	distal	-7	no	10.875	9.561	EPSD	COSMIC	9.847	Loss
CAMK_CAMK1_CAMK4_ST	P14866	HNRNPL	Q16566	CAMK4	S544	E540G	540	Missense	distal	-4	no	16.211	16.027	PhosphoSitePlus	COSMIC	9.847	Down-regulation
CAMK_CAMK1_CAMK4_ST	P14866	HNRNPL	Q16566	CAMK4	S544	R541C	541	Missense	distal	-3	no	16.211	10.139	PhosphoSitePlus	COSMIC	9.847	Down-regulation
CAMK_CAMK1_CAMK4_ST	P14866	HNRNPL	Q16566	CAMK4	S544	E540K	540	Missense	distal	-4	no	16.211	16.641	PhosphoSitePlus	COSMIC	9.847	Up-regulation
CAMK_CAMK1_CAMK4_ST	Q99623	PHB2	Q16566	CAMK4	S151	T155A	155	Missense	distal	4	no	9.464	10.067	EPSD	COSMIC	9.847	Gain
CAMK_CAMK1_CAMK4_ST	Q99623	PHB2	Q16566	CAMK4	T169	R166W	166	Missense	distal	-3	no	14.945	8.293	EPSD	COSMIC;CCLE	9.847	Loss
CAMK_CAMK1_CAMK4_ST	Q99623	PHB2	Q16566	CAMK4	T169	R165C	165	Missense	distal	-4	no	14.945	13.959	EPSD	COSMIC	9.847	Down-regulation
CAMK_CAMK1_CAMK4_ST	Q99623	PHB2	Q16566	CAMK4	S176	D180Y	180	Missense	distal	4	no	12.550	12.487	EPSD	COSMIC	9.847	Down-regulation
CAMK_CAMK1_CAMK4_ST	Q99623	PHB2	Q16566	CAMK4	T194	A196V	196	Missense	proximal	2	no	10.549	10.567	EPSD	COSMIC	9.847	Up-regulation
CAMK_CAMK1_CAMK4_ST	Q9UQM7	CAMK2A	Q16566	CAMK4	S314	K317T	317	Missense	distal	3	no	12.919	12.910	EPSD	COSMIC	9.847	Down-regulation
CAMK_CAMK1_CAMK4_ST	Q04206	RELA	Q16566	CAMK4	S45	E39Q	39	Missense	distal	-6	no	10.149	10.204	EPSD	COSMIC	9.847	Up-regulation
CAMK_CAMK1_CAMK4_ST	Q04206	RELA	Q16566	CAMK4	S131	R124W	124	Missense	distal	-7	no	10.188	8.155	EPSD	COSMIC	9.847	Loss
CAMK_CAMK1_CAMK4_ST	Q04206	RELA	Q16566	CAMK4	S269	R267C	267	Missense	proximal	-2	no	10.555	8.585	EPSD	COSMIC	9.847	Loss
CAMK_CAMK1_CAMK4_ST	Q04206	RELA	Q16566	CAMK4	S269	R274Q	274	Missense	distal	5	no	10.555	10.411	EPSD	COSMIC	9.847	Down-regulation
CAMK_CAMK1_CAMK4_ST	Q04206	RELA	Q16566	CAMK4	S276	D277N	277	Missense	proximal	1	no	14.867	15.051	EPSD	COSMIC;CCLE	9.847	Up-regulation
CAMK_CAMK1_CAMK4_ST	Q04206	RELA	Q16566	CAMK4	S276	R274Q	274	Missense	proximal	-2	no	14.867	13.514	EPSD	COSMIC	9.847	Down-regulation
CAMK_CAMK1_CAMK4_ST	Q04206	RELA	Q16566	CAMK4	S276	R278Q	278	Missense	proximal	2	no	14.867	14.899	EPSD	COSMIC	9.847	Up-regulation
CAMK_CAMK1_CAMK4_ST	Q04206	RELA	Q16566	CAMK4	S281	D277N	277	Missense	distal	-4	no	12.264	12.588	EPSD	COSMIC;CCLE	9.847	Up-regulation
CAMK_CAMK1_CAMK4_ST	Q04206	RELA	Q16566	CAMK4	S281	R274Q	274	Missense	distal	-7	no	12.264	10.692	EPSD	COSMIC	9.847	Down-regulation
CAMK_CAMK1_CAMK4_ST	Q04206	RELA	Q16566	CAMK4	S281	R278Q	278	Missense	distal	-3	no	12.264	7.581	EPSD	COSMIC	9.847	Loss
CAMK_CAMK1_CAMK4_ST	Q04206	RELA	Q16566	CAMK4	T305	R302C	302	Missense	distal	-3	no	10.192	4.121	EPSD	COSMIC	9.847	Loss
CAMK_CAMK1_CAMK4_ST	Q04206	RELA	Q16566	CAMK4	T305	E300K	300	Missense	distal	-5	no	10.192	10.794	EPSD	COSMIC	9.847	Up-regulation
CAMK_CAMK1_CAMK4_ST	Q04206	RELA	Q16566	CAMK4	T305	T305A	305	Missense	central	0	yes	10.192	0.000	EPSD	COSMIC	9.847	Loss
CAMK_CAMK1_CAMK4_ST	Q04206	RELA	Q16566	CAMK4	S337	P334S	334	Missense	distal	-3	no	11.395	12.964	EPSD	COSMIC	9.847	Up-regulation
CAMK_CAMK1_CAMK4_ST	Q04206	RELA	Q16566	CAMK4	S337	R330C	330	Missense	distal	-7	no	11.395	9.476	EPSD	COSMIC	9.847	Loss
CAMK_CAMK1_CAMK4_ST	Q04206	RELA	Q16566	CAMK4	S338	P334S	334	Missense	distal	-4	no	12.082	13.700	EPSD	COSMIC	9.847	Up-regulation
CAMK_CAMK1_CAMK4_ST	Q04206	RELA	Q16566	CAMK4	S340	P334S	334	Missense	distal	-6	no	11.357	11.415	EPSD	COSMIC	9.847	Up-regulation
CAMK_CAMK1_CAMK4_ST	Q04206	RELA	Q16566	CAMK4	S536	F534L	534	Missense	proximal	-2	no	12.028	11.551	PhosphoSitePlus	COSMIC	9.847	Down-regulation
CAMK_CAMK1_CAMK4_ST	P16949	STMN1	Q16566	CAMK4	S16	R14C	14	Missense	proximal	-2	no	14.860	12.891	PhosphoSitePlus	COSMIC	9.847	Down-regulation
CAMK_CAMK1_CAMK4_ST	P16949	STMN1	Q16566	CAMK4	S16	Q18E	18	Missense	proximal	2	no	14.860	14.864	PhosphoSitePlus	COSMIC	9.847	Up-regulation
CAMK_CAMK1_CAMK4_ST	P16949	STMN1	Q16566	CAMK4	S63	R61S	61	Missense	proximal	-2	no	14.468	14.151	EPSD	COSMIC	9.847	Down-regulation
CAMK_CAMKL_AMPK_PRKAA2_ST	Q13393	PLD1	P54646	PRKAA2	S505	P507L	507	Missense	proximal	2	no	70.246	64.133	PhosphoSitePlus	COSMIC	46.832	Down-regulation
CAMK_CAMKL_AMPK_PRKAA2_ST	Q13393	PLD1	P54646	PRKAA2	S505	S511F	511	Missense	distal	6	no	70.246	67.921	PhosphoSitePlus	COSMIC	46.832	Down-regulation
CAMK_CAMKL_AMPK_PRKAA2_ST	Q13393	PLD1	P54646	PRKAA2	S511	A516E	516	Missense	distal	5	no	53.367	53.049	EPSD	COSMIC	46.832	Down-regulation
CAMK_CAMKL_AMPK_PRKAA2_ST	Q13393	PLD1	P54646	PRKAA2	S511	M517K	517	Missense	distal	6	no	53.367	55.007	EPSD	COSMIC	46.832	Up-regulation
CAMK_CAMKL_AMPK_PRKAA2_ST	Q13393	PLD1	P54646	PRKAA2	S511	M517L	517	Missense	distal	6	no	53.367	54.852	EPSD	COSMIC	46.832	Up-regulation
CAMK_CAMKL_AMPK_PRKAA2_ST	Q13393	PLD1	P54646	PRKAA2	S511	P507L	507	Missense	distal	-4	no	53.367	51.634	EPSD	COSMIC	46.832	Down-regulation
CAMK_CAMKL_AMPK_PRKAA2_ST	Q13393	PLD1	P54646	PRKAA2	S511	S511F	511	Missense	central	0	yes	53.367	0.000	EPSD	COSMIC	46.832	Loss
CAMK_CAMKL_AMPK_PRKAA2_ST	Q13393	PLD1	P54646	PRKAA2	S519	A516E	516	Missense	distal	-3	no	49.678	48.689	EPSD	COSMIC	46.832	Down-regulation
CAMK_CAMKL_AMPK_PRKAA2_ST	Q13393	PLD1	P54646	PRKAA2	S519	M517K	517	Missense	proximal	-2	no	49.678	50.112	EPSD	COSMIC	46.832	Up-regulation
CAMK_CAMKL_AMPK_PRKAA2_ST	Q13393	PLD1	P54646	PRKAA2	S519	M517L	517	Missense	proximal	-2	no	49.678	53.261	EPSD	COSMIC	46.832	Up-regulation
CAMK_CAMKL_AMPK_PRKAA2_ST	Q13393	PLD1	P54646	PRKAA2	S519	S519F	519	Missense	central	0	yes	49.678	0.000	EPSD	COSMIC	46.832	Loss
CAMK_CAMKL_AMPK_PRKAA2_ST	Q13393	PLD1	P54646	PRKAA2	S558	G552R	552	Missense	distal	-6	no	52.395	52.555	EPSD	COSMIC	46.832	Up-regulation
CAMK_CAMKL_AMPK_PRKAA2_ST	Q13393	PLD1	P54646	PRKAA2	S558	R555I	555	Missense	distal	-3	no	52.395	39.425	EPSD	COSMIC	46.832	Loss
CAMK_CAMKL_AMPK_PRKAA2_ST	Q13393	PLD1	P54646	PRKAA2	S629	G633V	633	Missense	distal	4	no	42.873	47.294	EPSD	COSMIC	46.832	Gain
CAMK_CAMKL_AMPK_PRKAA2_ST	Q13393	PLD1	P54646	PRKAA2	T673	P674S	674	Missense	proximal	1	no	54.619	54.720	EPSD	COSMIC;GDSC;CCLE	46.832	Up-regulation
CAMK_CAMKL_AMPK_PRKAA2_ST	Q13393	PLD1	P54646	PRKAA2	T673	D680E	680	Missense	distal	7	no	54.619	55.071	EPSD	COSMIC	46.832	Up-regulation
CAMK_CAMKL_AMPK_PRKAA2_ST	Q13393	PLD1	P54646	PRKAA2	T673	I668F	668	Missense	distal	-5	no	54.619	58.059	EPSD	COSMIC;GDSC	46.832	Up-regulation
CAMK_CAMKL_AMPK_PRKAA2_ST	Q9UQL6	HDAC5	P54646	PRKAA2	S16	L20M	20	Missense	distal	4	no	53.127	47.740	EPSD	COSMIC	46.832	Down-regulation
CAMK_CAMKL_AMPK_PRKAA2_ST	Q9UQL6	HDAC5	P54646	PRKAA2	S16	R13W	13	Missense	distal	-3	no	53.127	36.983	EPSD	COSMIC	46.832	Loss
CAMK_CAMKL_AMPK_PRKAA2_ST	Q9UQL6	HDAC5	P54646	PRKAA2	S16	L17F	17	Missense	proximal	1	no	53.127	53.018	EPSD	COSMIC	46.832	Down-regulation
CAMK_CAMKL_AMPK_PRKAA2_ST	Q9UQL6	HDAC5	P54646	PRKAA2	S16	E18Q	18	Missense	proximal	2	no	53.127	53.121	EPSD	COSMIC	46.832	Down-regulation
CAMK_CAMKL_AMPK_PRKAA2_ST	Q9UQL6	HDAC5	P54646	PRKAA2	S16	G12R	12	Missense	distal	-4	no	53.127	55.072	EPSD	COSMIC	46.832	Up-regulation
CAMK_CAMKL_AMPK_PRKAA2_ST	Q9UQL6	HDAC5	P54646	PRKAA2	S55	R60W	60	Missense	distal	5	no	60.257	60.133	EPSD	COSMIC	46.832	Down-regulation
CAMK_CAMKL_AMPK_PRKAA2_ST	Q9UQL6	HDAC5	P54646	PRKAA2	S55	P54S	54	Missense	proximal	-1	no	60.257	60.559	EPSD	COSMIC	46.832	Up-regulation
CAMK_CAMKL_AMPK_PRKAA2_ST	Q9UQL6	HDAC5	P54646	PRKAA2	S55	R60L	60	Missense	distal	5	no	60.257	60.460	EPSD	COSMIC	46.832	Up-regulation
CAMK_CAMKL_AMPK_PRKAA2_ST	Q9UQL6	HDAC5	P54646	PRKAA2	S55	G51E	51	Missense	distal	-4	no	60.257	60.668	EPSD	COSMIC	46.832	Up-regulation
CAMK_CAMKL_AMPK_PRKAA2_ST	Q9UQL6	HDAC5	P54646	PRKAA2	S225	L221F	221	Missense	distal	-4	no	48.892	49.367	EPSD	COSMIC	46.832	Up-regulation
CAMK_CAMKL_AMPK_PRKAA2_ST	Q9UQL6	HDAC5	P54646	PRKAA2	S225	G230A	230	Missense	distal	5	no	48.892	48.932	EPSD	COSMIC	46.832	Up-regulation
CAMK_CAMKL_AMPK_PRKAA2_ST	Q9UQL6	HDAC5	P54646	PRKAA2	S225	P232L	232	Missense	distal	7	no	48.892	47.163	EPSD	COSMIC	46.832	Down-regulation
CAMK_CAMKL_AMPK_PRKAA2_ST	Q9UQL6	HDAC5	P54646	PRKAA2	S225	S224R	224	Missense	proximal	-1	no	48.892	48.594	EPSD	COSMIC	46.832	Down-regulation
CAMK_CAMKL_AMPK_PRKAA2_ST	Q9UQL6	HDAC5	P54646	PRKAA2	S225	G230R	230	Missense	distal	5	no	48.892	48.764	EPSD	COSMIC;CCLE	46.832	Down-regulation
CAMK_CAMKL_AMPK_PRKAA2_ST	Q9UQL6	HDAC5	P54646	PRKAA2	S225	G230D	230	Missense	distal	5	no	48.892	48.940	EPSD	COSMIC;CCLE	46.832	Up-regulation
CAMK_CAMKL_AMPK_PRKAA2_ST	Q9UQL6	HDAC5	P54646	PRKAA2	S225	G230S	230	Missense	distal	5	no	48.892	48.909	EPSD	COSMIC	46.832	Up-regulation
CAMK_CAMKL_AMPK_PRKAA2_ST	Q9UQL6	HDAC5	P54646	PRKAA2	S225	P232T	232	Missense	distal	7	no	48.892	47.975	EPSD	COSMIC	46.832	Down-regulation
CAMK_CAMKL_AMPK_PRKAA2_ST	Q9UQL6	HDAC5	P54646	PRKAA2	S259	R255C	255	Missense	distal	-4	no	73.186	72.240	EPSD;PhosphoSitePlus	COSMIC	46.832	Down-regulation
CAMK_CAMKL_AMPK_PRKAA2_ST	Q9UQL6	HDAC5	P54646	PRKAA2	S259	R266C	266	Missense	distal	7	no	73.186	74.659	EPSD;PhosphoSitePlus	COSMIC	46.832	Up-regulation
CAMK_CAMKL_AMPK_PRKAA2_ST	Q9UQL6	HDAC5	P54646	PRKAA2	S259	R266H	266	Missense	distal	7	no	73.186	72.811	EPSD;PhosphoSitePlus	COSMIC	46.832	Down-regulation
CAMK_CAMKL_AMPK_PRKAA2_ST	Q9UQL6	HDAC5	P54646	PRKAA2	S278	R284C	284	Missense	distal	6	no	56.110	53.265	EPSD	COSMIC	46.832	Down-regulation
CAMK_CAMKL_AMPK_PRKAA2_ST	Q9UQL6	HDAC5	P54646	PRKAA2	S278	S279N	279	Missense	proximal	1	no	56.110	55.998	EPSD	COSMIC	46.832	Down-regulation
CAMK_CAMKL_AMPK_PRKAA2_ST	Q9UQL6	HDAC5	P54646	PRKAA2	S278	R284S	284	Missense	distal	6	no	56.110	56.459	EPSD	COSMIC	46.832	Up-regulation
CAMK_CAMKL_AMPK_PRKAA2_ST	Q9UQL6	HDAC5	P54646	PRKAA2	T479	R476H	476	Missense	distal	-3	no	49.467	37.452	EPSD	COSMIC	46.832	Loss
CAMK_CAMKL_AMPK_PRKAA2_ST	Q9UQL6	HDAC5	P54646	PRKAA2	T479	T473M	473	Missense	distal	-6	no	49.467	48.032	EPSD	COSMIC	46.832	Down-regulation
CAMK_CAMKL_AMPK_PRKAA2_ST	Q9UQL6	HDAC5	P54646	PRKAA2	T479	G474C	474	Missense	distal	-5	no	49.467	37.829	EPSD	COSMIC	46.832	Loss
CAMK_CAMKL_AMPK_PRKAA2_ST	Q9UQL6	HDAC5	P54646	PRKAA2	T479	R476C	476	Missense	distal	-3	no	49.467	36.195	EPSD	COSMIC	46.832	Loss
CAMK_CAMKL_AMPK_PRKAA2_ST	Q9UQL6	HDAC5	P54646	PRKAA2	T479	T483M	483	Missense	distal	4	no	49.467	48.913	EPSD	COSMIC	46.832	Down-regulation
CAMK_CAMKL_AMPK_PRKAA2_ST	Q9UQL6	HDAC5	P54646	PRKAA2	T479	A478V	478	Missense	proximal	-1	no	49.467	49.284	EPSD	COSMIC;CCLE	46.832	Down-regulation
CAMK_CAMKL_AMPK_PRKAA2_ST	Q9UQL6	HDAC5	P54646	PRKAA2	T479	R482W	482	Missense	distal	3	no	49.467	51.172	EPSD	COSMIC	46.832	Up-regulation
CAMK_CAMKL_AMPK_PRKAA2_ST	Q9UQL6	HDAC5	P54646	PRKAA2	S498	R491W	491	Missense	distal	-7	no	77.858	77.839	PhosphoSitePlus;EPSD	COSMIC	46.832	Down-regulation
CAMK_CAMKL_AMPK_PRKAA2_ST	Q9UQL6	HDAC5	P54646	PRKAA2	T650	A649T	649	Missense	proximal	-1	no	48.761	48.530	EPSD	COSMIC	46.832	Down-regulation
CAMK_CAMKL_AMPK_PRKAA2_ST	Q9UQL6	HDAC5	P54646	PRKAA2	S661	R658L	658	Missense	distal	-3	no	55.873	44.917	EPSD	COSMIC	46.832	Loss
CAMK_CAMKL_AMPK_PRKAA2_ST	Q9UQL6	HDAC5	P54646	PRKAA2	S661	R658H	658	Missense	distal	-3	no	55.873	43.858	EPSD	COSMIC	46.832	Loss
CAMK_CAMKL_AMPK_PRKAA2_ST	Q9UQL6	HDAC5	P54646	PRKAA2	S661	T659S	659	Missense	proximal	-2	no	55.873	58.847	EPSD	COSMIC	46.832	Up-regulation
CAMK_CAMKL_AMPK_PRKAA2_ST	Q9UQL6	HDAC5	P54646	PRKAA2	S799	R802H	802	Missense	distal	3	no	50.436	53.399	EPSD	COSMIC	46.832	Up-regulation
CAMK_CAMKL_AMPK_PRKAA2_ST	Q9UQL6	HDAC5	P54646	PRKAA2	S799	W792L	792	Missense	distal	-7	no	50.436	50.617	EPSD	COSMIC	46.832	Up-regulation
CAMK_CAMKL_AMPK_PRKAA2_ST	Q9UQL6	HDAC5	P54646	PRKAA2	S799	S799R	799	Missense	central	0	yes	50.436	0.000	EPSD	COSMIC	46.832	Loss
CAMK_CAMKL_AMPK_PRKAA2_ST	Q9UQL6	HDAC5	P54646	PRKAA2	S799	V801M	801	Missense	proximal	2	no	50.436	46.220	EPSD	COSMIC	46.832	Loss
CAMK_CAMKL_AMPK_PRKAA2_ST	Q9UQL6	HDAC5	P54646	PRKAA2	S799	A804E	804	Missense	distal	5	no	50.436	50.118	EPSD	COSMIC	46.832	Down-regulation
CAMK_CAMKL_AMPK_PRKAA2_ST	P09874	PARP1	P54646	PRKAA2	S25	P29L	29	Missense	distal	4	no	47.150	55.484	EPSD	COSMIC	46.832	Up-regulation
CAMK_CAMKL_AMPK_PRKAA2_ST	P09874	PARP1	P54646	PRKAA2	S25	E26K	26	Missense	proximal	1	no	47.150	47.094	EPSD	COSMIC	46.832	Down-regulation
CAMK_CAMKL_AMPK_PRKAA2_ST	P09874	PARP1	P54646	PRKAA2	S25	R18H	18	Missense	distal	-7	no	47.150	46.873	EPSD	COSMIC	46.832	Down-regulation
CAMK_CAMKL_AMPK_PRKAA2_ST	P09874	PARP1	P54646	PRKAA2	S25	D31N	31	Missense	distal	6	no	47.150	49.179	EPSD	COSMIC	46.832	Up-regulation
CAMK_CAMKL_AMPK_PRKAA2_ST	P09874	PARP1	P54646	PRKAA2	S120	G127R	127	Missense	distal	7	no	53.928	53.624	EPSD	COSMIC	46.832	Down-regulation
CAMK_CAMKL_AMPK_PRKAA2_ST	P09874	PARP1	P54646	PRKAA2	S120	T124M	124	Missense	distal	4	no	53.928	53.373	EPSD	COSMIC	46.832	Down-regulation
CAMK_CAMKL_AMPK_PRKAA2_ST	P09874	PARP1	P54646	PRKAA2	S177	R173Q	173	Missense	distal	-4	no	72.801	71.606	PhosphoSitePlus	COSMIC	46.832	Down-regulation
CAMK_CAMKL_AMPK_PRKAA2_ST	P09874	PARP1	P54646	PRKAA2	S177	R173W	173	Missense	distal	-4	no	72.801	70.734	PhosphoSitePlus	COSMIC	46.832	Down-regulation
CAMK_CAMKL_AMPK_PRKAA2_ST	P09874	PARP1	P54646	PRKAA2	S177	G183S	183	Missense	distal	6	no	72.801	73.893	PhosphoSitePlus	COSMIC	46.832	Up-regulation
CAMK_CAMKL_AMPK_PRKAA2_ST	P09874	PARP1	P54646	PRKAA2	S177	F172V	172	Missense	distal	-5	no	72.801	70.087	PhosphoSitePlus	COSMIC	46.832	Down-regulation
CAMK_CAMKL_AMPK_PRKAA2_ST	P09874	PARP1	P54646	PRKAA2	S179	G183S	183	Missense	distal	4	no	40.570	47.137	EPSD	COSMIC	46.832	Gain
CAMK_CAMKL_AMPK_PRKAA2_ST	P09874	PARP1	P54646	PRKAA2	T368	P370S	370	Missense	proximal	2	no	47.400	45.230	EPSD	COSMIC	46.832	Loss
CAMK_CAMKL_AMPK_PRKAA2_ST	P09874	PARP1	P54646	PRKAA2	T368	T361N	361	Missense	distal	-7	no	47.400	47.500	EPSD	COSMIC	46.832	Up-regulation
CAMK_CAMKL_AMPK_PRKAA2_ST	P09874	PARP1	P54646	PRKAA2	T368	S372F	372	Missense	distal	4	no	47.400	50.917	EPSD	COSMIC	46.832	Up-regulation
CAMK_CAMKL_AMPK_PRKAA2_ST	P09874	PARP1	P54646	PRKAA2	T368	S364F	364	Missense	distal	-4	no	47.400	46.164	EPSD	COSMIC	46.832	Loss
CAMK_CAMKL_AMPK_PRKAA2_ST	P09874	PARP1	P54646	PRKAA2	S372	P377S	377	Missense	distal	5	no	49.979	50.105	EPSD	COSMIC	46.832	Up-regulation
CAMK_CAMKL_AMPK_PRKAA2_ST	P09874	PARP1	P54646	PRKAA2	S372	P370S	370	Missense	proximal	-2	no	49.979	49.408	EPSD	COSMIC	46.832	Down-regulation
CAMK_CAMKL_AMPK_PRKAA2_ST	P09874	PARP1	P54646	PRKAA2	S372	S372F	372	Missense	central	0	yes	49.979	0.000	EPSD	COSMIC	46.832	Loss
CAMK_CAMKL_AMPK_PRKAA2_ST	P09874	PARP1	P54646	PRKAA2	T373	P377S	377	Missense	distal	4	no	49.281	51.130	EPSD	COSMIC	46.832	Up-regulation
CAMK_CAMKL_AMPK_PRKAA2_ST	P09874	PARP1	P54646	PRKAA2	T373	V380M	380	Missense	distal	7	no	49.281	51.038	EPSD	COSMIC	46.832	Up-regulation
CAMK_CAMKL_AMPK_PRKAA2_ST	P09874	PARP1	P54646	PRKAA2	T373	P370S	370	Missense	distal	-3	no	49.281	50.667	EPSD	COSMIC	46.832	Up-regulation
CAMK_CAMKL_AMPK_PRKAA2_ST	P09874	PARP1	P54646	PRKAA2	T373	S372F	372	Missense	proximal	-1	no	49.281	48.740	EPSD	COSMIC	46.832	Down-regulation
CAMK_CAMKL_AMPK_PRKAA2_ST	P09874	PARP1	P54646	PRKAA2	S375	P377S	377	Missense	proximal	2	no	48.725	46.555	EPSD	COSMIC	46.832	Loss
CAMK_CAMKL_AMPK_PRKAA2_ST	P09874	PARP1	P54646	PRKAA2	S375	V380M	380	Missense	distal	5	no	48.725	48.706	EPSD	COSMIC	46.832	Down-regulation
CAMK_CAMKL_AMPK_PRKAA2_ST	P09874	PARP1	P54646	PRKAA2	S375	P370S	370	Missense	distal	-5	no	48.725	51.110	EPSD	COSMIC	46.832	Up-regulation
CAMK_CAMKL_AMPK_PRKAA2_ST	P09874	PARP1	P54646	PRKAA2	S375	S372F	372	Missense	distal	-3	no	48.725	44.043	EPSD	COSMIC	46.832	Loss
CAMK_CAMKL_AMPK_PRKAA2_ST	P09874	PARP1	P54646	PRKAA2	S455	S455F	455	Missense	central	0	yes	53.514	0.000	EPSD	COSMIC	46.832	Loss
CAMK_CAMKL_AMPK_PRKAA2_ST	P09874	PARP1	P54646	PRKAA2	S455	E448K	448	Missense	distal	-7	no	53.514	53.708	EPSD	COSMIC	46.832	Up-regulation
CAMK_CAMKL_AMPK_PRKAA2_ST	P09874	PARP1	P54646	PRKAA2	S455	E456K	456	Missense	proximal	1	no	53.514	53.458	EPSD	COSMIC	46.832	Down-regulation
CAMK_CAMKL_AMPK_PRKAA2_ST	P09874	PARP1	P54646	PRKAA2	S455	R452Q	452	Missense	distal	-3	no	53.514	39.249	EPSD	COSMIC	46.832	Loss
CAMK_CAMKL_AMPK_PRKAA2_ST	P09874	PARP1	P54646	PRKAA2	S499	A494T	494	Missense	distal	-5	no	58.269	58.872	EPSD	COSMIC	46.832	Up-regulation
CAMK_CAMKL_AMPK_PRKAA2_ST	P09874	PARP1	P54646	PRKAA2	S499	P495S	495	Missense	distal	-4	no	58.269	58.248	EPSD	COSMIC	46.832	Down-regulation
CAMK_CAMKL_AMPK_PRKAA2_ST	P09874	PARP1	P54646	PRKAA2	S499	K498E	498	Missense	proximal	-1	no	58.269	58.490	EPSD	COSMIC	46.832	Up-regulation
CAMK_CAMKL_AMPK_PRKAA2_ST	P09874	PARP1	P54646	PRKAA2	S499	S499L	499	Missense	central	0	yes	58.269	0.000	EPSD	COSMIC	46.832	Loss
CAMK_CAMKL_AMPK_PRKAA2_ST	O00418	EEF2K	P54646	PRKAA2	T364	T364N	364	Missense	central	0	yes	47.763	0.000	EPSD	COSMIC	46.832	Loss
CAMK_CAMKL_AMPK_PRKAA2_ST	O00418	EEF2K	P54646	PRKAA2	S377	E383D	383	Missense	distal	6	no	55.566	54.956	EPSD	COSMIC	46.832	Down-regulation
CAMK_CAMKL_AMPK_PRKAA2_ST	O00418	EEF2K	P54646	PRKAA2	S377	S377L	377	Missense	central	0	yes	55.566	0.000	EPSD	COSMIC	46.832	Loss
CAMK_CAMKL_AMPK_PRKAA2_ST	O00418	EEF2K	P54646	PRKAA2	S377	P375S	375	Missense	proximal	-2	no	55.566	54.995	EPSD	COSMIC	46.832	Down-regulation
CAMK_CAMKL_AMPK_PRKAA2_ST	O00418	EEF2K	P54646	PRKAA2	S386	V388M	388	Missense	proximal	2	no	54.363	50.147	EPSD	COSMIC;CCLE	46.832	Down-regulation
CAMK_CAMKL_AMPK_PRKAA2_ST	O00418	EEF2K	P54646	PRKAA2	S386	E383D	383	Missense	distal	-3	no	54.363	61.102	EPSD	COSMIC	46.832	Up-regulation
CAMK_CAMKL_AMPK_PRKAA2_ST	O00418	EEF2K	P54646	PRKAA2	S386	T389I	389	Missense	distal	3	no	54.363	48.320	EPSD	COSMIC	46.832	Down-regulation
CAMK_CAMKL_AMPK_PRKAA2_ST	O00418	EEF2K	P54646	PRKAA2	S395	S398C	398	Missense	distal	3	no	65.193	60.302	EPSD	COSMIC	46.832	Down-regulation
CAMK_CAMKL_AMPK_PRKAA2_ST	O00418	EEF2K	P54646	PRKAA2	S395	V388M	388	Missense	distal	-7	no	65.193	65.228	EPSD	COSMIC;CCLE	46.832	Up-regulation
CAMK_CAMKL_AMPK_PRKAA2_ST	O00418	EEF2K	P54646	PRKAA2	S395	T389I	389	Missense	distal	-6	no	65.193	63.372	EPSD	COSMIC	46.832	Down-regulation
CAMK_CAMKL_AMPK_PRKAA2_ST	O00418	EEF2K	P54646	PRKAA2	S395	S399L	399	Missense	distal	4	no	65.193	71.678	EPSD	COSMIC	46.832	Up-regulation
CAMK_CAMKL_AMPK_PRKAA2_ST	O00418	EEF2K	P54646	PRKAA2	S395	P394L	394	Missense	proximal	-1	no	65.193	65.569	EPSD	COSMIC;GDSC;CCLE	46.832	Up-regulation
CAMK_CAMKL_AMPK_PRKAA2_ST	O00418	EEF2K	P54646	PRKAA2	S395	P394S	394	Missense	proximal	-1	no	65.193	65.496	EPSD	COSMIC	46.832	Up-regulation
CAMK_CAMKL_AMPK_PRKAA2_ST	O00418	EEF2K	P54646	PRKAA2	S398	S398C	398	Missense	central	0	yes	66.424	0.000	PhosphoSitePlus	COSMIC	46.832	Loss
CAMK_CAMKL_AMPK_PRKAA2_ST	O00418	EEF2K	P54646	PRKAA2	S398	S399L	399	Missense	proximal	1	no	66.424	66.440	PhosphoSitePlus	COSMIC	46.832	Up-regulation
CAMK_CAMKL_AMPK_PRKAA2_ST	O00418	EEF2K	P54646	PRKAA2	S398	P394L	394	Missense	distal	-4	no	66.424	64.692	PhosphoSitePlus	COSMIC;GDSC;CCLE	46.832	Down-regulation
CAMK_CAMKL_AMPK_PRKAA2_ST	O00418	EEF2K	P54646	PRKAA2	S398	P394S	394	Missense	distal	-4	no	66.424	66.403	PhosphoSitePlus	COSMIC	46.832	Down-regulation
CAMK_CAMKL_AMPK_PRKAA2_ST	O00418	EEF2K	P54646	PRKAA2	S474	G476C	476	Missense	proximal	2	no	25.091	48.047	EPSD	COSMIC	46.832	Gain
CAMK_CAMKL_AMPK_PRKAA2_ST	O00418	EEF2K	P54646	PRKAA2	S492	R493C	493	Missense	proximal	1	no	56.130	56.123	EPSD	COSMIC	46.832	Down-regulation
CAMK_CAMKL_AMPK_PRKAA2_ST	P28562	DUSP1	P54646	PRKAA2	T141	S146T	146	Missense	distal	5	no	46.858	46.603	EPSD	COSMIC	46.832	Loss
CAMK_CAMKL_AMPK_PRKAA2_ST	P28562	DUSP1	P54646	PRKAA2	T141	S140L	140	Missense	proximal	-1	no	46.858	46.931	EPSD	COSMIC	46.832	Up-regulation
CAMK_CAMKL_AMPK_PRKAA2_ST	P28562	DUSP1	P54646	PRKAA2	S334	A327T	327	Missense	distal	-7	no	71.466	71.525	PhosphoSitePlus	COSMIC	46.832	Up-regulation
CAMK_CAMKL_AMPK_PRKAA2_ST	P30260	CDC27	P54646	PRKAA2	S192	Q187L	187	Missense	distal	-5	no	35.560	48.991	EPSD	COSMIC	46.832	Gain
CAMK_CAMKL_AMPK_PRKAA2_ST	P30260	CDC27	P54646	PRKAA2	S222	S220A	220	Missense	proximal	-2	no	49.547	47.789	EPSD	COSMIC	46.832	Down-regulation
CAMK_CAMKL_AMPK_PRKAA2_ST	P30260	CDC27	P54646	PRKAA2	S233	I240L	240	Missense	distal	7	no	58.460	57.417	EPSD	COSMIC	46.832	Down-regulation
CAMK_CAMKL_AMPK_PRKAA2_ST	P30260	CDC27	P54646	PRKAA2	S237	I240L	240	Missense	distal	3	no	45.447	50.269	EPSD	COSMIC	46.832	Gain
CAMK_CAMKL_AMPK_PRKAA2_ST	P30260	CDC27	P54646	PRKAA2	T279	A273T	273	Missense	distal	-6	no	51.368	52.210	EPSD	COSMIC;CCLE	46.832	Up-regulation
CAMK_CAMKL_AMPK_PRKAA2_ST	P30260	CDC27	P54646	PRKAA2	T313	K319N	319	Missense	distal	6	no	51.952	52.812	EPSD	COSMIC	46.832	Up-regulation
CAMK_CAMKL_AMPK_PRKAA2_ST	P30260	CDC27	P54646	PRKAA2	T313	S312P	312	Missense	proximal	-1	no	51.952	51.649	EPSD	COSMIC	46.832	Down-regulation
CAMK_CAMKL_AMPK_PRKAA2_ST	P30260	CDC27	P54646	PRKAA2	T313	K318E	318	Missense	distal	5	no	51.952	51.944	EPSD	COSMIC	46.832	Down-regulation
CAMK_CAMKL_AMPK_PRKAA2_ST	P30260	CDC27	P54646	PRKAA2	T313	S312C	312	Missense	proximal	-1	no	51.952	51.557	EPSD	COSMIC	46.832	Down-regulation
CAMK_CAMKL_AMPK_PRKAA2_ST	P30260	CDC27	P54646	PRKAA2	S320	K319N	319	Missense	proximal	-1	no	61.039	61.578	EPSD	COSMIC	46.832	Up-regulation
CAMK_CAMKL_AMPK_PRKAA2_ST	P30260	CDC27	P54646	PRKAA2	S320	K318E	318	Missense	proximal	-2	no	61.039	61.808	EPSD	COSMIC	46.832	Up-regulation
CAMK_CAMKL_AMPK_PRKAA2_ST	P30260	CDC27	P54646	PRKAA2	S334	K330Q	330	Missense	distal	-4	no	57.850	57.089	EPSD	COSMIC	46.832	Down-regulation
CAMK_CAMKL_AMPK_PRKAA2_ST	P30260	CDC27	P54646	PRKAA2	S334	E341K	341	Missense	distal	7	no	57.850	57.541	EPSD	COSMIC	46.832	Down-regulation
CAMK_CAMKL_AMPK_PRKAA2_ST	P30260	CDC27	P54646	PRKAA2	S334	S339I	339	Missense	distal	5	no	57.850	57.665	EPSD	COSMIC	46.832	Down-regulation
CAMK_CAMKL_AMPK_PRKAA2_ST	P30260	CDC27	P54646	PRKAA2	S334	T329A	329	Missense	distal	-5	no	57.850	57.248	EPSD	COSMIC	46.832	Down-regulation
CAMK_CAMKL_AMPK_PRKAA2_ST	P30260	CDC27	P54646	PRKAA2	T349	G353C	353	Missense	distal	4	no	50.899	40.171	EPSD	COSMIC	46.832	Loss
CAMK_CAMKL_AMPK_PRKAA2_ST	P30260	CDC27	P54646	PRKAA2	T349	G353R	353	Missense	distal	4	no	50.899	47.465	EPSD	COSMIC	46.832	Down-regulation
CAMK_CAMKL_AMPK_PRKAA2_ST	P30260	CDC27	P54646	PRKAA2	T358	G353C	353	Missense	distal	-5	no	54.049	42.411	EPSD	COSMIC	46.832	Loss
CAMK_CAMKL_AMPK_PRKAA2_ST	P30260	CDC27	P54646	PRKAA2	T358	G353R	353	Missense	distal	-5	no	54.049	47.472	EPSD	COSMIC	46.832	Down-regulation
CAMK_CAMKL_AMPK_PRKAA2_ST	P30260	CDC27	P54646	PRKAA2	T368	P371L	371	Missense	distal	3	no	45.954	47.610	EPSD	COSMIC	46.832	Gain
CAMK_CAMKL_AMPK_PRKAA2_ST	P30260	CDC27	P54646	PRKAA2	S369	T368A	368	Missense	proximal	-1	no	47.841	48.072	EPSD	COSMIC;CCLE	46.832	Up-regulation
CAMK_CAMKL_AMPK_PRKAA2_ST	P30260	CDC27	P54646	PRKAA2	S369	L374P	374	Missense	distal	5	no	47.841	47.657	EPSD	COSMIC	46.832	Down-regulation
CAMK_CAMKL_AMPK_PRKAA2_ST	P30260	CDC27	P54646	PRKAA2	S369	P371L	371	Missense	proximal	2	no	47.841	41.729	EPSD	COSMIC	46.832	Loss
CAMK_CAMKL_AMPK_PRKAA2_ST	P30260	CDC27	P54646	PRKAA2	S379	S378N	378	Missense	proximal	-1	no	64.169	64.263	PhosphoSitePlus	COSMIC	46.832	Up-regulation
CAMK_CAMKL_AMPK_PRKAA2_ST	P30260	CDC27	P54646	PRKAA2	S379	L374P	374	Missense	distal	-5	no	64.169	57.294	PhosphoSitePlus	COSMIC	46.832	Down-regulation
CAMK_CAMKL_AMPK_PRKAA2_ST	P30260	CDC27	P54646	PRKAA2	T383	S378N	378	Missense	distal	-5	no	50.736	51.642	EPSD	COSMIC	46.832	Up-regulation
CAMK_CAMKL_AMPK_PRKAA2_ST	P30260	CDC27	P54646	PRKAA2	T383	T389A	389	Missense	distal	6	no	50.736	53.314	EPSD	COSMIC	46.832	Up-regulation
CAMK_CAMKL_AMPK_PRKAA2_ST	P30260	CDC27	P54646	PRKAA2	S384	S378N	378	Missense	distal	-6	no	53.314	52.931	EPSD	COSMIC	46.832	Down-regulation
CAMK_CAMKL_AMPK_PRKAA2_ST	P30260	CDC27	P54646	PRKAA2	S384	T389A	389	Missense	distal	5	no	53.314	53.592	EPSD	COSMIC	46.832	Up-regulation
CAMK_CAMKL_AMPK_PRKAA2_ST	P30260	CDC27	P54646	PRKAA2	S435	E439K	439	Missense	distal	4	no	48.758	43.666	EPSD	COSMIC	46.832	Loss
CAMK_CAMKL_AMPK_PRKAA2_ST	P30260	CDC27	P54646	PRKAA2	S435	L432S	432	Missense	distal	-3	no	48.758	52.189	EPSD	COSMIC	46.832	Up-regulation
CAMK_CAMKL_AMPK_PRKAA2_ST	P30260	CDC27	P54646	PRKAA2	S435	K441I	441	Missense	distal	6	no	48.758	45.268	EPSD	COSMIC	46.832	Loss
CAMK_CAMKL_AMPK_PRKAA2_ST	P30260	CDC27	P54646	PRKAA2	S435	I442V	442	Missense	distal	7	no	48.758	49.129	EPSD	COSMIC	46.832	Up-regulation
CAMK_CAMKL_AMPK_PRKAA2_ST	P30260	CDC27	P54646	PRKAA2	S523	I521M	521	Missense	proximal	-2	no	51.334	51.375	EPSD	COSMIC	46.832	Up-regulation
CAMK_CAMKL_AMPK_PRKAA2_ST	P30260	CDC27	P54646	PRKAA2	S523	F522L	522	Missense	proximal	-1	no	51.334	51.949	EPSD	COSMIC	46.832	Up-regulation
CAMK_CAMKL_AMPK_PRKAA2_ST	P30260	CDC27	P54646	PRKAA2	S523	I521K	521	Missense	proximal	-2	no	51.334	51.808	EPSD	COSMIC	46.832	Up-regulation
CAMK_CAMKL_AMPK_PRKAA2_ST	P30260	CDC27	P54646	PRKAA2	S523	I521L	521	Missense	proximal	-2	no	51.334	54.957	EPSD	COSMIC	46.832	Up-regulation
CAMK_CAMKL_AMPK_PRKAA2_ST	P30260	CDC27	P54646	PRKAA2	S523	E529Q	529	Missense	distal	6	no	51.334	51.540	EPSD	COSMIC	46.832	Up-regulation
CAMK_CAMKL_AMPK_PRKAA2_ST	O43524	FOXO3	P54646	PRKAA2	S75	M77L	77	Missense	proximal	2	no	48.531	47.600	EPSD	COSMIC	46.832	Down-regulation
CAMK_CAMKL_AMPK_PRKAA2_ST	O43524	FOXO3	P54646	PRKAA2	T179	P174S	174	Missense	distal	-5	no	67.236	69.620	EPSD;PhosphoSitePlus	COSMIC	46.832	Up-regulation
CAMK_CAMKL_AMPK_PRKAA2_ST	O43524	FOXO3	P54646	PRKAA2	T179	E185K	185	Missense	distal	6	no	67.236	67.795	EPSD;PhosphoSitePlus	COSMIC	46.832	Up-regulation
CAMK_CAMKL_AMPK_PRKAA2_ST	O43524	FOXO3	P54646	PRKAA2	S253	S253F	253	Missense	central	0	yes	51.904	0.000	EPSD	COSMIC	46.832	Loss
CAMK_CAMKL_AMPK_PRKAA2_ST	O43524	FOXO3	P54646	PRKAA2	S253	R248W	248	Missense	distal	-5	no	51.904	51.207	EPSD	COSMIC	46.832	Down-regulation
CAMK_CAMKL_AMPK_PRKAA2_ST	O43524	FOXO3	P54646	PRKAA2	S300	P295L	295	Missense	distal	-5	no	46.231	53.106	EPSD	COSMIC	46.832	Gain
CAMK_CAMKL_AMPK_PRKAA2_ST	O43524	FOXO3	P54646	PRKAA2	S315	S318C	318	Missense	distal	3	no	54.324	49.432	EPSD	COSMIC	46.832	Down-regulation
CAMK_CAMKL_AMPK_PRKAA2_ST	O43524	FOXO3	P54646	PRKAA2	T319	S318C	318	Missense	proximal	-1	no	52.081	51.686	EPSD	COSMIC	46.832	Down-regulation
CAMK_CAMKL_AMPK_PRKAA2_ST	O43524	FOXO3	P54646	PRKAA2	T319	R323C	323	Missense	distal	4	no	52.081	44.787	EPSD	COSMIC	46.832	Loss
CAMK_CAMKL_AMPK_PRKAA2_ST	O43524	FOXO3	P54646	PRKAA2	T319	R323H	323	Missense	distal	4	no	52.081	37.957	EPSD	COSMIC	46.832	Loss
CAMK_CAMKL_AMPK_PRKAA2_ST	O43524	FOXO3	P54646	PRKAA2	S357	P361L	361	Missense	distal	4	no	40.215	48.549	EPSD	COSMIC;GDSC;CCLE	46.832	Gain
CAMK_CAMKL_AMPK_PRKAA2_ST	O43524	FOXO3	P54646	PRKAA2	T363	P367L	367	Missense	distal	4	no	49.334	57.667	EPSD	COSMIC	46.832	Up-regulation
CAMK_CAMKL_AMPK_PRKAA2_ST	O43524	FOXO3	P54646	PRKAA2	T363	T370N	370	Missense	distal	7	no	49.334	49.225	EPSD	COSMIC	46.832	Down-regulation
CAMK_CAMKL_AMPK_PRKAA2_ST	O43524	FOXO3	P54646	PRKAA2	T363	P361L	361	Missense	proximal	-2	no	49.334	48.387	EPSD	COSMIC;GDSC;CCLE	46.832	Down-regulation
CAMK_CAMKL_AMPK_PRKAA2_ST	O43524	FOXO3	P54646	PRKAA2	T363	T363A	363	Missense	central	0	yes	49.334	0.000	EPSD	COSMIC;GDSC;CCLE	46.832	Loss
CAMK_CAMKL_AMPK_PRKAA2_ST	O43524	FOXO3	P54646	PRKAA2	T395	P397R	397	Missense	proximal	2	no	47.132	41.835	EPSD	COSMIC	46.832	Loss
CAMK_CAMKL_AMPK_PRKAA2_ST	O43524	FOXO3	P54646	PRKAA2	S399	P397R	397	Missense	proximal	-2	no	65.379	64.979	EPSD;PhosphoSitePlus	COSMIC	46.832	Down-regulation
CAMK_CAMKL_AMPK_PRKAA2_ST	O43524	FOXO3	P54646	PRKAA2	S413	F414Y	414	Missense	proximal	1	no	68.510	68.355	EPSD;PhosphoSitePlus	COSMIC	46.832	Down-regulation
CAMK_CAMKL_AMPK_PRKAA2_ST	O43524	FOXO3	P54646	PRKAA2	S428	G424V	424	Missense	distal	-4	no	47.039	48.121	EPSD	COSMIC	46.832	Up-regulation
CAMK_CAMKL_AMPK_PRKAA2_ST	O43524	FOXO3	P54646	PRKAA2	S429	G424V	424	Missense	distal	-5	no	48.023	46.896	EPSD	COSMIC	46.832	Down-regulation
CAMK_CAMKL_AMPK_PRKAA2_ST	O43524	FOXO3	P54646	PRKAA2	S551	M557R	557	Missense	distal	6	no	54.803	56.171	EPSD	COSMIC	46.832	Up-regulation
CAMK_CAMKL_AMPK_PRKAA2_ST	O43524	FOXO3	P54646	PRKAA2	S555	M557R	557	Missense	proximal	2	no	66.106	65.990	EPSD;PhosphoSitePlus	COSMIC	46.832	Down-regulation
CAMK_CAMKL_AMPK_PRKAA2_ST	O43524	FOXO3	P54646	PRKAA2	S588	T582P	582	Missense	distal	-6	no	75.453	74.646	EPSD;PhosphoSitePlus	COSMIC	46.832	Down-regulation
CAMK_CAMKL_AMPK_PRKAA2_ST	P08151	GLI1	P54646	PRKAA2	T63	G65C	65	Missense	proximal	2	no	36.275	59.231	EPSD	COSMIC	46.832	Gain
CAMK_CAMKL_AMPK_PRKAA2_ST	P08151	GLI1	P54646	PRKAA2	S84	S84F	84	Missense	central	0	yes	47.664	0.000	EPSD	COSMIC	46.832	Loss
CAMK_CAMKL_AMPK_PRKAA2_ST	P08151	GLI1	P54646	PRKAA2	S84	L88M	88	Missense	distal	4	no	47.664	42.278	EPSD	COSMIC	46.832	Loss
CAMK_CAMKL_AMPK_PRKAA2_ST	P08151	GLI1	P54646	PRKAA2	S89	S84F	84	Missense	distal	-5	no	54.351	56.826	EPSD	COSMIC	46.832	Up-regulation
CAMK_CAMKL_AMPK_PRKAA2_ST	P08151	GLI1	P54646	PRKAA2	S89	S92N	92	Missense	distal	3	no	54.351	53.825	EPSD	COSMIC	46.832	Down-regulation
CAMK_CAMKL_AMPK_PRKAA2_ST	P08151	GLI1	P54646	PRKAA2	S89	L88M	88	Missense	proximal	-1	no	54.351	53.885	EPSD	COSMIC	46.832	Down-regulation
CAMK_CAMKL_AMPK_PRKAA2_ST	P08151	GLI1	P54646	PRKAA2	S89	L95M	95	Missense	distal	6	no	54.351	52.866	EPSD	COSMIC	46.832	Down-regulation
CAMK_CAMKL_AMPK_PRKAA2_ST	P08151	GLI1	P54646	PRKAA2	S102	S105L	105	Missense	distal	3	no	69.119	67.039	EPSD;PhosphoSitePlus	COSMIC	46.832	Down-regulation
CAMK_CAMKL_AMPK_PRKAA2_ST	P08151	GLI1	P54646	PRKAA2	S102	P103R	103	Missense	proximal	1	no	69.119	69.021	EPSD;PhosphoSitePlus	COSMIC	46.832	Down-regulation
CAMK_CAMKL_AMPK_PRKAA2_ST	P08151	GLI1	P54646	PRKAA2	S102	P103S	103	Missense	proximal	1	no	69.119	69.221	EPSD;PhosphoSitePlus	COSMIC	46.832	Up-regulation
CAMK_CAMKL_AMPK_PRKAA2_ST	P08151	GLI1	P54646	PRKAA2	S102	V107I	107	Missense	distal	5	no	69.119	69.113	EPSD;PhosphoSitePlus	COSMIC	46.832	Down-regulation
CAMK_CAMKL_AMPK_PRKAA2_ST	P08151	GLI1	P54646	PRKAA2	S102	S105F	105	Missense	distal	3	no	69.119	64.956	EPSD;PhosphoSitePlus	COSMIC	46.832	Down-regulation
CAMK_CAMKL_AMPK_PRKAA2_ST	P08151	GLI1	P54646	PRKAA2	S102	L95M	95	Missense	distal	-7	no	69.119	68.978	EPSD;PhosphoSitePlus	COSMIC	46.832	Down-regulation
CAMK_CAMKL_AMPK_PRKAA2_ST	P08151	GLI1	P54646	PRKAA2	S102	S105Y	105	Missense	distal	3	no	69.119	63.334	EPSD;PhosphoSitePlus	COSMIC;GDSC	46.832	Down-regulation
CAMK_CAMKL_AMPK_PRKAA2_ST	P08151	GLI1	P54646	PRKAA2	S102	A108V	108	Missense	distal	6	no	69.119	62.842	EPSD;PhosphoSitePlus	COSMIC	46.832	Down-regulation
CAMK_CAMKL_AMPK_PRKAA2_ST	P08151	GLI1	P54646	PRKAA2	S102	S105T	105	Missense	distal	3	no	69.119	68.260	EPSD;PhosphoSitePlus	COSMIC	46.832	Down-regulation
CAMK_CAMKL_AMPK_PRKAA2_ST	P08151	GLI1	P54646	PRKAA2	T205	L211M	211	Missense	distal	6	no	47.728	46.244	EPSD	COSMIC	46.832	Loss
CAMK_CAMKL_AMPK_PRKAA2_ST	P08151	GLI1	P54646	PRKAA2	T205	P210A	210	Missense	distal	5	no	47.728	47.877	EPSD	COSMIC	46.832	Up-regulation
CAMK_CAMKL_AMPK_PRKAA2_ST	P08151	GLI1	P54646	PRKAA2	T205	M199V	199	Missense	distal	-6	no	47.728	47.443	EPSD	COSMIC	46.832	Down-regulation
CAMK_CAMKL_AMPK_PRKAA2_ST	P08151	GLI1	P54646	PRKAA2	T205	Q208L	208	Missense	distal	3	no	47.728	46.466	EPSD	COSMIC;GDSC	46.832	Loss
CAMK_CAMKL_AMPK_PRKAA2_ST	P08151	GLI1	P54646	PRKAA2	T205	D198Y	198	Missense	distal	-7	no	47.728	47.045	EPSD	COSMIC	46.832	Down-regulation
CAMK_CAMKL_AMPK_PRKAA2_ST	P08151	GLI1	P54646	PRKAA2	T205	Q208R	208	Missense	distal	3	no	47.728	43.780	EPSD	COSMIC	46.832	Loss
CAMK_CAMKL_AMPK_PRKAA2_ST	P08151	GLI1	P54646	PRKAA2	T374	C369F	369	Missense	distal	-5	no	39.630	52.855	EPSD	COSMIC	46.832	Gain
CAMK_CAMKL_AMPK_PRKAA2_ST	P08151	GLI1	P54646	PRKAA2	S408	S410C	410	Missense	proximal	2	no	68.083	69.993	PhosphoSitePlus;EPSD	COSMIC	46.832	Up-regulation
CAMK_CAMKL_AMPK_PRKAA2_ST	P08151	GLI1	P54646	PRKAA2	S408	P407S	407	Missense	proximal	-1	no	68.083	68.386	PhosphoSitePlus;EPSD	COSMIC	46.832	Up-regulation
CAMK_CAMKL_AMPK_PRKAA2_ST	P08151	GLI1	P54646	PRKAA2	S408	S408P	408	Missense	central	0	yes	68.083	0.000	PhosphoSitePlus;EPSD	COSMIC	46.832	Loss
CAMK_CAMKL_AMPK_PRKAA2_ST	P08151	GLI1	P54646	PRKAA2	S408	P414S	414	Missense	distal	6	no	68.083	70.244	PhosphoSitePlus;EPSD	COSMIC	46.832	Up-regulation
CAMK_CAMKL_AMPK_PRKAA2_ST	P08151	GLI1	P54646	PRKAA2	S408	R405Q	405	Missense	distal	-3	no	68.083	53.818	PhosphoSitePlus;EPSD	COSMIC	46.832	Down-regulation
CAMK_CAMKL_AMPK_PRKAA2_ST	P08151	GLI1	P54646	PRKAA2	S408	P414L	414	Missense	distal	6	no	68.083	70.012	PhosphoSitePlus;EPSD	COSMIC	46.832	Up-regulation
CAMK_CAMKL_AMPK_PRKAA2_ST	P08151	GLI1	P54646	PRKAA2	S408	K415Q	415	Missense	distal	7	no	68.083	67.403	PhosphoSitePlus;EPSD	COSMIC	46.832	Down-regulation
CAMK_CAMKL_AMPK_PRKAA2_ST	P08151	GLI1	P54646	PRKAA2	S410	P414L	414	Missense	distal	4	no	40.398	48.732	EPSD	COSMIC	46.832	Gain
CAMK_CAMKL_AMPK_PRKAA2_ST	P08151	GLI1	P54646	PRKAA2	S521	T514I	514	Missense	distal	-7	no	55.210	54.614	EPSD	COSMIC	46.832	Down-regulation
CAMK_CAMKL_AMPK_PRKAA2_ST	P08151	GLI1	P54646	PRKAA2	S521	G516S	516	Missense	distal	-5	no	55.210	54.322	EPSD	COSMIC	46.832	Down-regulation
CAMK_CAMKL_AMPK_PRKAA2_ST	P08151	GLI1	P54646	PRKAA2	S521	T525N	525	Missense	distal	4	no	55.210	49.882	EPSD	COSMIC	46.832	Down-regulation
CAMK_CAMKL_AMPK_PRKAA2_ST	P08151	GLI1	P54646	PRKAA2	S521	T525I	525	Missense	distal	4	no	55.210	52.723	EPSD	COSMIC	46.832	Down-regulation
CAMK_CAMKL_AMPK_PRKAA2_ST	P08151	GLI1	P54646	PRKAA2	S545	S538C	538	Missense	distal	-7	no	59.044	58.459	EPSD	COSMIC	46.832	Down-regulation
CAMK_CAMKL_AMPK_PRKAA2_ST	P08151	GLI1	P54646	PRKAA2	S545	R541C	541	Missense	distal	-4	no	59.044	58.097	EPSD	COSMIC;GDSC;CCLE	46.832	Down-regulation
CAMK_CAMKL_AMPK_PRKAA2_ST	P08151	GLI1	P54646	PRKAA2	S545	S550G	550	Missense	distal	5	no	59.044	59.026	EPSD	COSMIC	46.832	Down-regulation
CAMK_CAMKL_AMPK_PRKAA2_ST	P08151	GLI1	P54646	PRKAA2	S545	S548N	548	Missense	distal	3	no	59.044	58.518	EPSD	COSMIC	46.832	Down-regulation
CAMK_CAMKL_AMPK_PRKAA2_ST	P08151	GLI1	P54646	PRKAA2	S934	L931R	931	Missense	distal	-3	no	45.395	56.351	EPSD	COSMIC	46.832	Gain
CAMK_CAMKL_AMPK_PRKAA2_ST	P08151	GLI1	P54646	PRKAA2	S934	K929T	929	Missense	distal	-5	no	45.395	57.660	EPSD	COSMIC	46.832	Gain
CAMK_CAMKL_AMPK_PRKAA2_ST	P08151	GLI1	P54646	PRKAA2	S937	R940Q	940	Missense	distal	3	no	48.235	52.184	EPSD	COSMIC	46.832	Up-regulation
CAMK_CAMKL_AMPK_PRKAA2_ST	P08151	GLI1	P54646	PRKAA2	S937	R940W	940	Missense	distal	3	no	48.235	49.940	EPSD	COSMIC	46.832	Up-regulation
CAMK_CAMKL_AMPK_PRKAA2_ST	P08151	GLI1	P54646	PRKAA2	S937	L931R	931	Missense	distal	-6	no	48.235	49.051	EPSD	COSMIC	46.832	Up-regulation
CAMK_CAMKL_AMPK_PRKAA2_ST	P08151	GLI1	P54646	PRKAA2	S937	G933D	933	Missense	distal	-4	no	48.235	50.001	EPSD	COSMIC	46.832	Up-regulation
CAMK_CAMKL_AMPK_PRKAA2_ST	P08151	GLI1	P54646	PRKAA2	S937	G932E	932	Missense	distal	-5	no	48.235	44.741	EPSD	COSMIC;CCLE	46.832	Loss
CAMK_CAMKL_AMPK_PRKAA2_ST	P08151	GLI1	P54646	PRKAA2	S937	R940C	940	Missense	distal	3	no	48.235	48.111	EPSD	COSMIC	46.832	Down-regulation
CAMK_CAMKL_AMPK_PRKAA2_ST	P08151	GLI1	P54646	PRKAA2	S937	S934F	934	Missense	distal	-3	no	48.235	43.553	EPSD	COSMIC	46.832	Loss
CAMK_CAMKL_AMPK_PRKAA2_ST	P08151	GLI1	P54646	PRKAA2	S937	A941T	941	Missense	distal	4	no	48.235	54.498	EPSD	COSMIC	46.832	Up-regulation
CAMK_CAMKL_AMPK_PRKAA2_ST	P08151	GLI1	P54646	PRKAA2	S1071	R1068Q	1068	Missense	distal	-3	no	47.458	33.192	EPSD	COSMIC	46.832	Loss
CAMK_CAMKL_AMPK_PRKAA2_ST	P08151	GLI1	P54646	PRKAA2	S1071	R1068W	1068	Missense	distal	-3	no	47.458	31.314	EPSD	COSMIC	46.832	Loss
CAMK_CAMKL_AMPK_PRKAA2_ST	P08151	GLI1	P54646	PRKAA2	S1071	H1065N	1065	Missense	distal	-6	no	47.458	48.369	EPSD	COSMIC	46.832	Up-regulation
CAMK_CAMKL_AMPK_PRKAA2_ST	P08151	GLI1	P54646	PRKAA2	S1071	S1064P	1064	Missense	distal	-7	no	47.458	47.312	EPSD	COSMIC	46.832	Down-regulation
CAMK_CAMKL_AMPK_PRKAA2_ST	P08151	GLI1	P54646	PRKAA2	S1071	P1077H	1077	Missense	distal	6	no	47.458	48.177	EPSD	COSMIC	46.832	Up-regulation
CAMK_CAMKL_AMPK_PRKAA2_ST	P08151	GLI1	P54646	PRKAA2	T1074	R1068Q	1068	Missense	distal	-6	no	66.875	67.073	EPSD;PhosphoSitePlus	COSMIC	46.832	Up-regulation
CAMK_CAMKL_AMPK_PRKAA2_ST	P08151	GLI1	P54646	PRKAA2	T1074	R1068W	1068	Missense	distal	-6	no	66.875	66.546	EPSD;PhosphoSitePlus	COSMIC	46.832	Down-regulation
CAMK_CAMKL_AMPK_PRKAA2_ST	P08151	GLI1	P54646	PRKAA2	T1074	P1077H	1077	Missense	distal	3	no	66.875	68.809	EPSD;PhosphoSitePlus	COSMIC	46.832	Up-regulation
CAMK_CAMKL_AMPK_PRKAA2_ST	Q9BZL4	PPP1R12C	P54646	PRKAA2	T290	G285D	285	Missense	distal	-5	no	51.675	44.967	EPSD	COSMIC;CCLE	46.832	Loss
CAMK_CAMKL_AMPK_PRKAA2_ST	Q9BZL4	PPP1R12C	P54646	PRKAA2	S325	G329S	329	Missense	distal	4	no	53.368	59.935	EPSD	COSMIC	46.832	Up-regulation
CAMK_CAMKL_AMPK_PRKAA2_ST	Q9BZL4	PPP1R12C	P54646	PRKAA2	S344	S338N	338	Missense	distal	-6	no	55.060	54.677	EPSD	COSMIC	46.832	Down-regulation
CAMK_CAMKL_AMPK_PRKAA2_ST	Q9BZL4	PPP1R12C	P54646	PRKAA2	S399	P400L	400	Missense	proximal	1	no	54.644	54.761	EPSD	COSMIC	46.832	Up-regulation
CAMK_CAMKL_AMPK_PRKAA2_ST	Q9BZL4	PPP1R12C	P54646	PRKAA2	S399	P403R	403	Missense	distal	4	no	54.644	46.491	EPSD	COSMIC	46.832	Loss
CAMK_CAMKL_AMPK_PRKAA2_ST	Q9BZL4	PPP1R12C	P54646	PRKAA2	S450	S454F	454	Missense	distal	4	no	44.769	48.287	EPSD	COSMIC	46.832	Gain
CAMK_CAMKL_AMPK_PRKAA2_ST	Q9BZL4	PPP1R12C	P54646	PRKAA2	S452	S454F	454	Missense	proximal	2	no	70.646	56.435	PhosphoSitePlus	COSMIC	46.832	Down-regulation
CAMK_CAMKL_AMPK_PRKAA2_ST	Q9BZL4	PPP1R12C	P54646	PRKAA2	S452	Q448K	448	Missense	distal	-4	no	70.646	71.408	PhosphoSitePlus	COSMIC	46.832	Up-regulation
CAMK_CAMKL_AMPK_PRKAA2_ST	Q9BZL4	PPP1R12C	P54646	PRKAA2	S509	A511E	511	Missense	proximal	2	no	55.078	49.753	EPSD	COSMIC	46.832	Down-regulation
CAMK_CAMKL_AMPK_PRKAA2_ST	Q9BZL4	PPP1R12C	P54646	PRKAA2	S509	A511V	511	Missense	proximal	2	no	55.078	58.247	EPSD	COSMIC	46.832	Up-regulation
CAMK_CAMKL_AMPK_PRKAA2_ST	Q9BZL4	PPP1R12C	P54646	PRKAA2	S559	S559F	559	Missense	central	0	yes	49.854	0.000	EPSD	COSMIC	46.832	Loss
CAMK_CAMKL_AMPK_PRKAA2_ST	Q9BZL4	PPP1R12C	P54646	PRKAA2	S559	Q561H	561	Missense	proximal	2	no	49.854	47.533	EPSD	COSMIC	46.832	Down-regulation
CAMK_CAMKL_AMPK_PRKAA2_ST	Q9BXM7	PINK1	P54646	PRKAA2	S284	R279H	279	Missense	distal	-5	no	70.151	56.541	EPSD;PhosphoSitePlus	COSMIC	46.832	Down-regulation
CAMK_CAMKL_AMPK_PRKAA2_ST	Q9BXM7	PINK1	P54646	PRKAA2	S284	P289S	289	Missense	distal	5	no	70.151	70.277	EPSD;PhosphoSitePlus	COSMIC	46.832	Up-regulation
CAMK_CAMKL_AMPK_PRKAA2_ST	Q9BXM7	PINK1	P54646	PRKAA2	S284	V285M	285	Missense	proximal	1	no	70.151	70.224	EPSD;PhosphoSitePlus	COSMIC	46.832	Up-regulation
CAMK_CAMKL_AMPK_PRKAA2_ST	Q92819	HAS2	P54646	PRKAA2	T110	T110A	110	Missense	central	0	yes	64.631	0.000	PhosphoSitePlus	COSMIC	46.832	Loss
CAMK_CAMKL_AMPK_PRKAA2_ST	Q92819	HAS2	P54646	PRKAA2	T110	G113W	113	Missense	distal	3	no	64.631	62.607	PhosphoSitePlus	COSMIC	46.832	Down-regulation
CAMK_CAMKL_AMPK_PRKAA2_ST	Q92819	HAS2	P54646	PRKAA2	S334	L337F	337	Missense	distal	3	no	50.856	48.774	EPSD	COSMIC	46.832	Down-regulation
CAMK_CAMKL_AMPK_PRKAA2_ST	Q92819	HAS2	P54646	PRKAA2	S440	M444L	444	Missense	distal	4	no	44.081	49.468	EPSD	COSMIC;GDSC;CCLE	46.832	Gain
CAMK_CAMKL_AMPK_PRKAA2_ST	Q9UQB8	BAIAP2	P54646	PRKAA2	S259	S263F	263	Missense	distal	4	no	55.506	59.024	EPSD	COSMIC	46.832	Up-regulation
CAMK_CAMKL_AMPK_PRKAA2_ST	Q9UQB8	BAIAP2	P54646	PRKAA2	S259	L265P	265	Missense	distal	6	no	55.506	53.578	EPSD	COSMIC	46.832	Down-regulation
CAMK_CAMKL_AMPK_PRKAA2_ST	Q9UQB8	BAIAP2	P54646	PRKAA2	S261	S263F	263	Missense	proximal	2	no	54.374	40.163	EPSD	COSMIC	46.832	Loss
CAMK_CAMKL_AMPK_PRKAA2_ST	Q9UQB8	BAIAP2	P54646	PRKAA2	S261	L265P	265	Missense	distal	4	no	54.374	46.040	EPSD	COSMIC	46.832	Loss
CAMK_CAMKL_AMPK_PRKAA2_ST	Q9UQB8	BAIAP2	P54646	PRKAA2	S263	L265P	265	Missense	proximal	2	no	42.756	48.869	EPSD	COSMIC	46.832	Gain
CAMK_CAMKL_AMPK_PRKAA2_ST	Q9UQB8	BAIAP2	P54646	PRKAA2	S323	S323F	323	Missense	central	0	yes	49.561	0.000	EPSD	COSMIC	46.832	Loss
CAMK_CAMKL_AMPK_PRKAA2_ST	Q9UQB8	BAIAP2	P54646	PRKAA2	S323	R316H	316	Missense	distal	-7	no	49.561	49.284	EPSD	COSMIC	46.832	Down-regulation
CAMK_CAMKL_AMPK_PRKAA2_ST	Q9UQB8	BAIAP2	P54646	PRKAA2	S323	R316C	316	Missense	distal	-7	no	49.561	49.258	EPSD	COSMIC	46.832	Down-regulation
CAMK_CAMKL_AMPK_PRKAA2_ST	Q9UQB8	BAIAP2	P54646	PRKAA2	S323	A319S	319	Missense	distal	-4	no	49.561	50.951	EPSD	COSMIC	46.832	Up-regulation
CAMK_CAMKL_AMPK_PRKAA2_ST	Q9UQB8	BAIAP2	P54646	PRKAA2	S325	S323F	323	Missense	proximal	-2	no	53.701	47.392	EPSD	COSMIC	46.832	Down-regulation
CAMK_CAMKL_AMPK_PRKAA2_ST	Q9UQB8	BAIAP2	P54646	PRKAA2	S325	S331N	331	Missense	distal	6	no	53.701	54.485	EPSD	COSMIC;GDSC;CCLE	46.832	Up-regulation
CAMK_CAMKL_AMPK_PRKAA2_ST	Q9UQB8	BAIAP2	P54646	PRKAA2	S325	A319S	319	Missense	distal	-6	no	53.701	55.097	EPSD	COSMIC	46.832	Up-regulation
CAMK_CAMKL_AMPK_PRKAA2_ST	Q9UQB8	BAIAP2	P54646	PRKAA2	S329	S323F	323	Missense	distal	-6	no	55.272	53.944	EPSD	COSMIC	46.832	Down-regulation
CAMK_CAMKL_AMPK_PRKAA2_ST	Q9UQB8	BAIAP2	P54646	PRKAA2	S329	S331N	331	Missense	proximal	2	no	55.272	45.604	EPSD	COSMIC;GDSC;CCLE	46.832	Loss
CAMK_CAMKL_AMPK_PRKAA2_ST	Q9UQB8	BAIAP2	P54646	PRKAA2	S334	S331N	331	Missense	distal	-3	no	57.884	55.865	EPSD	COSMIC;GDSC;CCLE	46.832	Down-regulation
CAMK_CAMKL_AMPK_PRKAA2_ST	Q9UQB8	BAIAP2	P54646	PRKAA2	S336	S331N	331	Missense	distal	-5	no	53.770	54.676	EPSD	COSMIC;GDSC;CCLE	46.832	Up-regulation
CAMK_CAMKL_AMPK_PRKAA2_ST	Q9UQB8	BAIAP2	P54646	PRKAA2	S336	P342H	342	Missense	distal	6	no	53.770	54.490	EPSD	COSMIC	46.832	Up-regulation
CAMK_CAMKL_AMPK_PRKAA2_ST	Q9UQB8	BAIAP2	P54646	PRKAA2	S336	V343M	343	Missense	distal	7	no	53.770	55.527	EPSD	COSMIC	46.832	Up-regulation
CAMK_CAMKL_AMPK_PRKAA2_ST	Q9UQB8	BAIAP2	P54646	PRKAA2	S336	P342S	342	Missense	distal	6	no	53.770	55.931	EPSD	COSMIC	46.832	Up-regulation
CAMK_CAMKL_AMPK_PRKAA2_ST	Q9UQB8	BAIAP2	P54646	PRKAA2	T360	A354T	354	Missense	distal	-6	no	49.934	50.776	EPSD	COSMIC	46.832	Up-regulation
CAMK_CAMKL_AMPK_PRKAA2_ST	Q9UQB8	BAIAP2	P54646	PRKAA2	T360	R363C	363	Missense	distal	3	no	49.934	49.810	EPSD	COSMIC	46.832	Down-regulation
CAMK_CAMKL_AMPK_PRKAA2_ST	Q9UQB8	BAIAP2	P54646	PRKAA2	T360	S364N	364	Missense	distal	4	no	49.934	46.259	EPSD	COSMIC	46.832	Loss
CAMK_CAMKL_AMPK_PRKAA2_ST	Q9UQB8	BAIAP2	P54646	PRKAA2	S366	L371M	371	Missense	distal	5	no	65.938	65.682	PhosphoSitePlus	COSMIC	46.832	Down-regulation
CAMK_CAMKL_AMPK_PRKAA2_ST	Q9UQB8	BAIAP2	P54646	PRKAA2	S366	A369D	369	Missense	distal	3	no	65.938	67.133	PhosphoSitePlus	COSMIC	46.832	Up-regulation
CAMK_CAMKL_AMPK_PRKAA2_ST	Q9UQB8	BAIAP2	P54646	PRKAA2	S366	R373C	373	Missense	distal	7	no	65.938	67.411	PhosphoSitePlus	COSMIC	46.832	Up-regulation
CAMK_CAMKL_AMPK_PRKAA2_ST	Q9UQB8	BAIAP2	P54646	PRKAA2	S366	R363C	363	Missense	distal	-3	no	65.938	52.666	PhosphoSitePlus	COSMIC	46.832	Down-regulation
CAMK_CAMKL_AMPK_PRKAA2_ST	Q9UQB8	BAIAP2	P54646	PRKAA2	S366	S364N	364	Missense	proximal	-2	no	65.938	63.671	PhosphoSitePlus	COSMIC	46.832	Down-regulation
CAMK_CAMKL_AMPK_PRKAA2_ST	Q9UQB8	BAIAP2	P54646	PRKAA2	S391	G388R	388	Missense	distal	-3	no	38.495	50.430	EPSD	COSMIC	46.832	Gain
CAMK_CAMKL_AMPK_PRKAA2_ST	Q9UQB8	BAIAP2	P54646	PRKAA2	T392	L393I	393	Missense	proximal	1	no	52.040	51.851	EPSD	COSMIC	46.832	Down-regulation
CAMK_CAMKL_AMPK_PRKAA2_ST	Q9UQB8	BAIAP2	P54646	PRKAA2	T392	G388E	388	Missense	distal	-4	no	52.040	52.452	EPSD	COSMIC;GDSC;CCLE	46.832	Up-regulation
CAMK_CAMKL_AMPK_PRKAA2_ST	Q9UQB8	BAIAP2	P54646	PRKAA2	T392	T392I	392	Missense	central	0	yes	52.040	0.000	EPSD	COSMIC	46.832	Loss
CAMK_CAMKL_AMPK_PRKAA2_ST	Q9UQB8	BAIAP2	P54646	PRKAA2	T392	G388R	388	Missense	distal	-4	no	52.040	53.985	EPSD	COSMIC	46.832	Up-regulation
CAMK_CAMKL_AMPK_PRKAA2_ST	Q9UQB8	BAIAP2	P54646	PRKAA2	T392	L393H	393	Missense	proximal	1	no	52.040	51.882	EPSD	COSMIC	46.832	Down-regulation
CAMK_CAMKL_AMPK_PRKAA2_ST	Q9UQB8	BAIAP2	P54646	PRKAA2	T392	L394R	394	Missense	proximal	2	no	52.040	52.855	EPSD	COSMIC	46.832	Up-regulation
CAMK_CAMKL_AMPK_PRKAA2_ST	Q9UQB8	BAIAP2	P54646	PRKAA2	T392	A387T	387	Missense	distal	-5	no	52.040	52.643	EPSD	COSMIC	46.832	Up-regulation
CAMK_CAMKL_AMPK_PRKAA2_ST	Q13177	PAK2	P54646	PRKAA2	S19	I22M	22	Missense	distal	3	no	48.254	48.108	EPSD	COSMIC	46.832	Down-regulation
CAMK_CAMKL_AMPK_PRKAA2_ST	Q13177	PAK2	P54646	PRKAA2	S19	P15H	15	Missense	distal	-4	no	48.254	47.362	EPSD	COSMIC	46.832	Down-regulation
CAMK_CAMKL_AMPK_PRKAA2_ST	Q13177	PAK2	P54646	PRKAA2	S20	I22M	22	Missense	proximal	2	no	62.155	58.689	PhosphoSitePlus	COSMIC	46.832	Down-regulation
CAMK_CAMKL_AMPK_PRKAA2_ST	Q13177	PAK2	P54646	PRKAA2	S20	P15H	15	Missense	distal	-5	no	62.155	45.241	PhosphoSitePlus	COSMIC	46.832	Loss
CAMK_CAMKL_AMPK_PRKAA2_ST	Q13177	PAK2	P54646	PRKAA2	T195	R196Q	196	Missense	proximal	1	no	51.250	51.340	EPSD	COSMIC	46.832	Up-regulation
CAMK_CAMKL_AMPK_PRKAA2_ST	Q13177	PAK2	P54646	PRKAA2	S398	G405R	405	Missense	distal	7	no	50.360	50.056	EPSD	COSMIC	46.832	Down-regulation
CAMK_CAMKL_AMPK_PRKAA2_ST	Q13177	PAK2	P54646	PRKAA2	S398	P395H	395	Missense	distal	-3	no	50.360	47.256	EPSD	COSMIC	46.832	Down-regulation
CAMK_CAMKL_AMPK_PRKAA2_ST	O14920	IKBKB	P54646	PRKAA2	S177	E172G	172	Missense	distal	-5	no	74.270	77.764	PhosphoSitePlus;EPSD	COSMIC	46.832	Up-regulation
CAMK_CAMKL_AMPK_PRKAA2_ST	O14920	IKBKB	P54646	PRKAA2	S177	K171E	171	Missense	distal	-6	no	74.270	73.588	PhosphoSitePlus;EPSD	COSMIC;CCLE	46.832	Down-regulation
CAMK_CAMKL_AMPK_PRKAA2_ST	O14920	IKBKB	P54646	PRKAA2	S177	A170T	170	Missense	distal	-7	no	74.270	74.328	PhosphoSitePlus;EPSD	COSMIC	46.832	Up-regulation
CAMK_CAMKL_AMPK_PRKAA2_ST	O14920	IKBKB	P54646	PRKAA2	S177	K171T	171	Missense	distal	-6	no	74.270	74.605	PhosphoSitePlus;EPSD	COSMIC	46.832	Up-regulation
CAMK_CAMKL_AMPK_PRKAA2_ST	O14920	IKBKB	P54646	PRKAA2	S177	K171M	171	Missense	distal	-6	no	74.270	73.170	PhosphoSitePlus;EPSD	COSMIC	46.832	Down-regulation
CAMK_CAMKL_AMPK_PRKAA2_ST	O14920	IKBKB	P54646	PRKAA2	S177	K171Q	171	Missense	distal	-6	no	74.270	74.215	PhosphoSitePlus;EPSD	COSMIC	46.832	Down-regulation
CAMK_CAMKL_AMPK_PRKAA2_ST	O14920	IKBKB	P54646	PRKAA2	T368	G374R	374	Missense	distal	6	no	51.577	52.321	EPSD	COSMIC	46.832	Up-regulation
CAMK_CAMKL_AMPK_PRKAA2_ST	O14920	IKBKB	P54646	PRKAA2	T368	P363H	363	Missense	distal	-5	no	51.577	34.664	EPSD	COSMIC	46.832	Loss
CAMK_CAMKL_AMPK_PRKAA2_ST	O14920	IKBKB	P54646	PRKAA2	T368	G374S	374	Missense	distal	6	no	51.577	52.670	EPSD	COSMIC;GDSC;CCLE	46.832	Up-regulation
CAMK_CAMKL_AMPK_PRKAA2_ST	O14920	IKBKB	P54646	PRKAA2	T368	K375T	375	Missense	distal	7	no	51.577	52.055	EPSD	COSMIC	46.832	Up-regulation
CAMK_CAMKL_AMPK_PRKAA2_ST	O14920	IKBKB	P54646	PRKAA2	S372	G374R	374	Missense	proximal	2	no	33.403	51.322	EPSD	COSMIC	46.832	Gain
CAMK_CAMKL_AMPK_PRKAA2_ST	O14920	IKBKB	P54646	PRKAA2	S372	G374S	374	Missense	proximal	2	no	33.403	54.449	EPSD	COSMIC;GDSC;CCLE	46.832	Gain
CAMK_CAMKL_AMPK_PRKAA2_ST	O14920	IKBKB	P54646	PRKAA2	S409	R404L	404	Missense	distal	-5	no	41.256	51.435	EPSD	COSMIC	46.832	Gain
CAMK_CAMKL_AMPK_PRKAA2_ST	O14920	IKBKB	P54646	PRKAA2	S675	D674N	674	Missense	proximal	-1	no	50.915	51.448	EPSD	COSMIC	46.832	Up-regulation
CAMK_CAMKL_AMPK_PRKAA2_ST	O14920	IKBKB	P54646	PRKAA2	S675	N677D	677	Missense	proximal	2	no	50.915	48.266	EPSD	COSMIC;GDSC;CCLE	46.832	Down-regulation
CAMK_CAMKL_AMPK_PRKAA2_ST	O14920	IKBKB	P54646	PRKAA2	S675	S679F	679	Missense	distal	4	no	50.915	54.432	EPSD	COSMIC	46.832	Up-regulation
CAMK_CAMKL_AMPK_PRKAA2_ST	O14920	IKBKB	P54646	PRKAA2	S675	R680P	680	Missense	distal	5	no	50.915	50.934	EPSD	COSMIC	46.832	Up-regulation
CAMK_CAMKL_AMPK_PRKAA2_ST	O14920	IKBKB	P54646	PRKAA2	S675	A678V	678	Missense	distal	3	no	50.915	45.847	EPSD	COSMIC	46.832	Loss
CAMK_CAMKL_AMPK_PRKAA2_ST	O14920	IKBKB	P54646	PRKAA2	S689	Q683K	683	Missense	distal	-6	no	47.393	47.449	EPSD	COSMIC	46.832	Up-regulation
CAMK_CAMKL_AMPK_PRKAA2_ST	O14920	IKBKB	P54646	PRKAA2	S689	T693M	693	Missense	distal	4	no	47.393	46.838	EPSD	COSMIC;CCLE	46.832	Down-regulation
CAMK_CAMKL_AMPK_PRKAA2_ST	O14920	IKBKB	P54646	PRKAA2	S689	A694V	694	Missense	distal	5	no	47.393	47.192	EPSD	COSMIC	46.832	Down-regulation
CAMK_CAMKL_AMPK_PRKAA2_ST	O14920	IKBKB	P54646	PRKAA2	S689	T693A	693	Missense	distal	4	no	47.393	41.131	EPSD	COSMIC	46.832	Loss
CAMK_CAMKL_AMPK_PRKAA2_ST	O14920	IKBKB	P54646	PRKAA2	S689	S689F	689	Missense	central	0	yes	47.393	0.000	EPSD	COSMIC	46.832	Loss
CAMK_CAMKL_AMPK_PRKAA2_ST	O14920	IKBKB	P54646	PRKAA2	S692	T693M	693	Missense	proximal	1	no	50.831	50.750	EPSD	COSMIC;CCLE	46.832	Down-regulation
CAMK_CAMKL_AMPK_PRKAA2_ST	O14920	IKBKB	P54646	PRKAA2	S692	A694V	694	Missense	proximal	2	no	50.831	54.000	EPSD	COSMIC	46.832	Up-regulation
CAMK_CAMKL_AMPK_PRKAA2_ST	O14920	IKBKB	P54646	PRKAA2	S692	T693A	693	Missense	proximal	1	no	50.831	50.817	EPSD	COSMIC	46.832	Down-regulation
CAMK_CAMKL_AMPK_PRKAA2_ST	O14920	IKBKB	P54646	PRKAA2	S692	S689F	689	Missense	distal	-3	no	50.831	46.149	EPSD	COSMIC	46.832	Loss
CAMK_CAMKL_AMPK_PRKAA2_ST	O14920	IKBKB	P54646	PRKAA2	T693	T693M	693	Missense	central	0	yes	55.094	0.000	EPSD	COSMIC;CCLE	46.832	Loss
CAMK_CAMKL_AMPK_PRKAA2_ST	O14920	IKBKB	P54646	PRKAA2	T693	A694V	694	Missense	proximal	1	no	55.094	54.953	EPSD	COSMIC	46.832	Down-regulation
CAMK_CAMKL_AMPK_PRKAA2_ST	O14920	IKBKB	P54646	PRKAA2	T693	T693A	693	Missense	central	0	yes	55.094	0.000	EPSD	COSMIC	46.832	Loss
CAMK_CAMKL_AMPK_PRKAA2_ST	O14920	IKBKB	P54646	PRKAA2	T693	S689F	689	Missense	distal	-4	no	55.094	53.858	EPSD	COSMIC	46.832	Down-regulation
CAMK_CAMKL_AMPK_PRKAA2_ST	O14920	IKBKB	P54646	PRKAA2	S697	K703E	703	Missense	distal	6	no	49.686	49.127	EPSD	COSMIC	46.832	Down-regulation
CAMK_CAMKL_AMPK_PRKAA2_ST	O14920	IKBKB	P54646	PRKAA2	S697	T693M	693	Missense	distal	-4	no	49.686	49.414	EPSD	COSMIC;CCLE	46.832	Down-regulation
CAMK_CAMKL_AMPK_PRKAA2_ST	O14920	IKBKB	P54646	PRKAA2	S697	A694V	694	Missense	distal	-3	no	49.686	50.184	EPSD	COSMIC	46.832	Up-regulation
CAMK_CAMKL_AMPK_PRKAA2_ST	O14920	IKBKB	P54646	PRKAA2	S697	T693A	693	Missense	distal	-4	no	49.686	49.415	EPSD	COSMIC	46.832	Down-regulation
CAMK_CAMKL_AMPK_PRKAA2_ST	P05549	TFAP2A	P54646	PRKAA2	S119	P123L	123	Missense	distal	4	no	47.541	55.875	EPSD	COSMIC	46.832	Up-regulation
CAMK_CAMKL_AMPK_PRKAA2_ST	P05549	TFAP2A	P54646	PRKAA2	S119	R125Q	125	Missense	distal	6	no	47.541	47.460	EPSD	COSMIC	46.832	Down-regulation
CAMK_CAMKL_AMPK_PRKAA2_ST	P05549	TFAP2A	P54646	PRKAA2	S187	S187C	187	Missense	central	0	yes	56.740	0.000	EPSD	COSMIC	46.832	Loss
CAMK_CAMKL_AMPK_PRKAA2_ST	P05549	TFAP2A	P54646	PRKAA2	S187	S187F	187	Missense	central	0	yes	56.740	0.000	EPSD	COSMIC	46.832	Loss
CAMK_CAMKL_AMPK_PRKAA2_ST	P05549	TFAP2A	P54646	PRKAA2	S187	S183F	183	Missense	distal	-4	no	56.740	55.504	EPSD	COSMIC	46.832	Down-regulation
CAMK_CAMKL_AMPK_PRKAA2_ST	P05549	TFAP2A	P54646	PRKAA2	S191	S187C	187	Missense	distal	-4	no	49.438	48.407	EPSD	COSMIC	46.832	Down-regulation
CAMK_CAMKL_AMPK_PRKAA2_ST	P05549	TFAP2A	P54646	PRKAA2	S191	S187F	187	Missense	distal	-4	no	49.438	48.202	EPSD	COSMIC	46.832	Down-regulation
CAMK_CAMKL_AMPK_PRKAA2_ST	P05549	TFAP2A	P54646	PRKAA2	S219	G216C	216	Missense	distal	-3	no	67.563	66.226	PhosphoSitePlus	COSMIC;GDSC;CCLE	46.832	Down-regulation
CAMK_CAMKL_AMPK_PRKAA2_ST	P05549	TFAP2A	P54646	PRKAA2	S219	S213L	213	Missense	distal	-6	no	67.563	65.604	PhosphoSitePlus	COSMIC	46.832	Down-regulation
CAMK_CAMKL_AMPK_PRKAA2_ST	P05549	TFAP2A	P54646	PRKAA2	S219	L221I	221	Missense	proximal	2	no	67.563	71.960	PhosphoSitePlus	COSMIC	46.832	Up-regulation
CAMK_CAMKL_AMPK_PRKAA2_ST	P05549	TFAP2A	P54646	PRKAA2	S239	P240A	240	Missense	proximal	1	no	50.389	50.410	EPSD	COSMIC	46.832	Up-regulation
CAMK_CAMKL_AMPK_PRKAA2_ST	P05549	TFAP2A	P54646	PRKAA2	S239	P240R	240	Missense	proximal	1	no	50.389	50.292	EPSD	COSMIC	46.832	Down-regulation
CAMK_CAMKL_AMPK_PRKAA2_ST	P05549	TFAP2A	P54646	PRKAA2	S239	R236W	236	Missense	distal	-3	no	50.389	34.246	EPSD	COSMIC	46.832	Loss
AGC_NDR_NDR_STK38L_ST	O60285	NUAK1	Q9Y2H1	STK38L	S600	R595H	595	Missense	distal	-5	no	2.145	2.684	EPSD	COSMIC	2.379	Gain
AGC_NDR_NDR_STK38L_ST	O60285	NUAK1	Q9Y2H1	STK38L	S636	R629W	629	Missense	distal	-7	no	2.432	2.437	EPSD	COSMIC;GDSC	2.379	Up-regulation
AGC_NDR_NDR_STK38L_ST	O60285	NUAK1	Q9Y2H1	STK38L	S636	F637V	637	Missense	proximal	1	no	2.432	2.206	EPSD	COSMIC;GDSC;CCLE	2.379	Loss
AGC_NDR_NDR_STK38L_ST	O60285	NUAK1	Q9Y2H1	STK38L	S636	R629Q	629	Missense	distal	-7	no	2.432	2.424	EPSD	COSMIC;CCLE	2.379	Down-regulation
AGC_NDR_NDR_STK38L_ST	Q96QF0	RAB3IP	Q9Y2H1	STK38L	T141	A138T	138	Missense	distal	-3	no	2.261	2.397	EPSD	COSMIC	2.379	Gain
AGC_NDR_NDR_STK38L_ST	Q96QF0	RAB3IP	Q9Y2H1	STK38L	S154	S147I	147	Missense	distal	-7	no	3.223	3.215	EPSD	COSMIC	2.379	Down-regulation
AGC_NDR_NDR_STK38L_ST	Q96QF0	RAB3IP	Q9Y2H1	STK38L	S154	R160S	160	Missense	distal	6	no	3.223	3.232	EPSD	COSMIC	2.379	Up-regulation
AGC_NDR_NDR_STK38L_ST	Q96QF0	RAB3IP	Q9Y2H1	STK38L	T257	V252A	252	Missense	distal	-5	no	2.497	2.978	EPSD	COSMIC	2.379	Up-regulation
AGC_NDR_NDR_STK38L_ST	Q96QF0	RAB3IP	Q9Y2H1	STK38L	T257	L258P	258	Missense	proximal	1	no	2.497	2.381	EPSD	COSMIC	2.379	Down-regulation
AGC_NDR_NDR_STK38L_ST	Q96QF0	RAB3IP	Q9Y2H1	STK38L	T257	E251K	251	Missense	distal	-6	no	2.497	2.484	EPSD	COSMIC	2.379	Down-regulation
AGC_NDR_NDR_STK38L_ST	Q96QF0	RAB3IP	Q9Y2H1	STK38L	T257	P264A	264	Missense	distal	7	no	2.497	2.457	EPSD	COSMIC	2.379	Down-regulation
AGC_NDR_NDR_STK38L_ST	Q96QF0	RAB3IP	Q9Y2H1	STK38L	T257	A254T	254	Missense	distal	-3	no	2.497	2.633	EPSD	COSMIC	2.379	Up-regulation
AGC_NDR_NDR_STK38L_ST	Q96QF0	RAB3IP	Q9Y2H1	STK38L	S266	T265K	265	Missense	proximal	-1	no	2.583	2.720	EPSD	COSMIC	2.379	Up-regulation
AGC_NDR_NDR_STK38L_ST	Q96QF0	RAB3IP	Q9Y2H1	STK38L	S266	P264A	264	Missense	proximal	-2	no	2.583	2.597	EPSD	COSMIC	2.379	Up-regulation
AGC_NDR_NDR_STK38L_ST	Q96QF0	RAB3IP	Q9Y2H1	STK38L	S288	A292V	292	Missense	distal	4	no	8.086	6.997	PhosphoSitePlus	COSMIC	2.379	Down-regulation
AGC_NDR_NDR_STK38L_ST	P46937	YAP1	Q9Y2H1	STK38L	S103	R106G	106	Missense	distal	3	no	1.920	2.778	EPSD	COSMIC	2.379	Gain
AGC_NDR_NDR_STK38L_ST	P46937	YAP1	Q9Y2H1	STK38L	S105	R106G	106	Missense	proximal	1	no	3.816	3.892	EPSD	COSMIC	2.379	Up-regulation
AGC_NDR_NDR_STK38L_ST	P46937	YAP1	Q9Y2H1	STK38L	S105	S105P	105	Missense	central	0	yes	3.816	0.000	EPSD	COSMIC	2.379	Loss
AGC_NDR_NDR_STK38L_ST	P46937	YAP1	Q9Y2H1	STK38L	S105	K102R	102	Missense	distal	-3	no	3.816	3.903	EPSD	COSMIC	2.379	Up-regulation
AGC_NDR_NDR_STK38L_ST	P46937	YAP1	Q9Y2H1	STK38L	S109	R106G	106	Missense	distal	-3	no	2.488	2.310	EPSD	COSMIC	2.379	Loss
AGC_NDR_NDR_STK38L_ST	P46937	YAP1	Q9Y2H1	STK38L	S109	S105P	105	Missense	distal	-4	no	2.488	2.634	EPSD	COSMIC	2.379	Up-regulation
AGC_NDR_NDR_STK38L_ST	P46937	YAP1	Q9Y2H1	STK38L	S109	K102R	102	Missense	distal	-7	no	2.488	2.490	EPSD	COSMIC	2.379	Up-regulation
AGC_NDR_NDR_STK38L_ST	P46937	YAP1	Q9Y2H1	STK38L	S127	L132R	132	Missense	distal	5	no	9.436	9.254	PhosphoSitePlus	COSMIC	2.379	Down-regulation
AGC_NDR_NDR_STK38L_ST	P46937	YAP1	Q9Y2H1	STK38L	S127	Q133H	133	Missense	distal	6	no	9.436	9.275	PhosphoSitePlus	COSMIC	2.379	Down-regulation
AGC_NDR_NDR_STK38L_ST	P46937	YAP1	Q9Y2H1	STK38L	S127	S127F	127	Missense	central	0	yes	9.436	0.000	PhosphoSitePlus	COSMIC	2.379	Loss
AGC_NDR_NDR_STK38L_ST	P46937	YAP1	Q9Y2H1	STK38L	S127	A125G	125	Missense	proximal	-2	no	9.436	9.275	PhosphoSitePlus	COSMIC	2.379	Down-regulation
AGC_NDR_NDR_STK38L_ST	P46937	YAP1	Q9Y2H1	STK38L	T154	A152T	152	Missense	proximal	-2	no	2.447	2.375	EPSD	COSMIC	2.379	Loss
AGC_NDR_NDR_STK38L_ST	P46937	YAP1	Q9Y2H1	STK38L	T154	P151A	151	Missense	distal	-3	no	2.447	2.317	EPSD	COSMIC	2.379	Loss
AGC_NDR_NDR_STK38L_ST	P46937	YAP1	Q9Y2H1	STK38L	T154	L160H	160	Missense	distal	6	no	2.447	2.296	EPSD	COSMIC	2.379	Loss
AGC_NDR_NDR_STK38L_ST	P46937	YAP1	Q9Y2H1	STK38L	S163	I167T	167	Missense	distal	4	no	2.081	2.770	EPSD	COSMIC	2.379	Gain
AGC_NDR_NDR_STK38L_ST	P46937	YAP1	Q9Y2H1	STK38L	S163	E166G	166	Missense	distal	3	no	2.081	2.590	EPSD	COSMIC	2.379	Gain
AGC_NDR_NDR_STK38L_ST	P46937	YAP1	Q9Y2H1	STK38L	S289	P284L	284	Missense	distal	-5	no	3.334	3.320	EPSD	COSMIC	2.379	Down-regulation
AGC_NDR_NDR_STK38L_ST	P46937	YAP1	Q9Y2H1	STK38L	S336	A338T	338	Missense	proximal	2	no	3.535	3.552	EPSD	COSMIC	2.379	Up-regulation
AGC_NDR_NDR_STK38L_ST	P46937	YAP1	Q9Y2H1	STK38L	S336	M330I	330	Missense	distal	-6	no	3.535	3.495	EPSD	COSMIC;GDSC	2.379	Down-regulation
AGC_NDR_NDR_STK38L_ST	P46937	YAP1	Q9Y2H1	STK38L	S336	S340A	340	Missense	distal	4	no	3.535	3.541	EPSD	COSMIC;GDSC	2.379	Up-regulation
AGC_NDR_NDR_STK38L_ST	P46937	YAP1	Q9Y2H1	STK38L	T378	N380T	380	Missense	proximal	2	no	3.593	3.484	EPSD	COSMIC	2.379	Down-regulation
AGC_NDR_NDR_STK38L_ST	P46937	YAP1	Q9Y2H1	STK38L	T378	S382C	382	Missense	distal	4	no	3.593	3.047	EPSD	COSMIC	2.379	Down-regulation
AGC_NDR_NDR_STK38L_ST	P46937	YAP1	Q9Y2H1	STK38L	T378	D383H	383	Missense	distal	5	no	3.593	3.589	EPSD	COSMIC	2.379	Down-regulation
AGC_NDR_NDR_STK38L_ST	P46937	YAP1	Q9Y2H1	STK38L	T378	T378I	378	Missense	central	0	yes	3.593	0.000	EPSD	COSMIC	2.379	Loss
AGC_NDR_NDR_STK38L_ST	P46937	YAP1	Q9Y2H1	STK38L	T378	S371F	371	Missense	distal	-7	no	3.593	3.585	EPSD	COSMIC	2.379	Down-regulation
AGC_NDR_NDR_STK38L_ST	P46937	YAP1	Q9Y2H1	STK38L	T378	D383G	383	Missense	distal	5	no	3.593	3.741	EPSD	COSMIC	2.379	Up-regulation
AGC_NDR_NDR_STK38L_ST	P46937	YAP1	Q9Y2H1	STK38L	T378	S382T	382	Missense	distal	4	no	3.593	3.223	EPSD	COSMIC	2.379	Down-regulation
AGC_NDR_NDR_STK38L_ST	P46937	YAP1	Q9Y2H1	STK38L	T378	F385L	385	Missense	distal	7	no	3.593	3.608	EPSD	COSMIC	2.379	Up-regulation
AGC_NDR_NDR_STK38L_ST	P46937	YAP1	Q9Y2H1	STK38L	T378	T376A	376	Missense	proximal	-2	no	3.593	3.665	EPSD	COSMIC	2.379	Up-regulation
AGC_NDR_NDR_STK38L_ST	P46937	YAP1	Q9Y2H1	STK38L	T378	T376P	376	Missense	proximal	-2	no	3.593	3.651	EPSD	COSMIC	2.379	Up-regulation
AGC_NDR_NDR_STK38L_ST	P46937	YAP1	Q9Y2H1	STK38L	T378	T378M	378	Missense	central	0	yes	3.593	0.000	EPSD	COSMIC	2.379	Loss
AGC_NDR_NDR_STK38L_ST	P46937	YAP1	Q9Y2H1	STK38L	T378	M377V	377	Missense	proximal	-1	no	3.593	3.549	EPSD	COSMIC	2.379	Down-regulation
AGC_NDR_NDR_STK38L_ST	P46937	YAP1	Q9Y2H1	STK38L	T378	M377I	377	Missense	proximal	-1	no	3.593	3.529	EPSD	COSMIC;GDSC;CCLE	2.379	Down-regulation
AGC_NDR_NDR_STK38L_ST	P46937	YAP1	Q9Y2H1	STK38L	T379	D383H	383	Missense	distal	4	no	2.065	2.432	EPSD	COSMIC	2.379	Gain
AGC_NDR_NDR_STK38L_ST	P46937	YAP1	Q9Y2H1	STK38L	T379	D383G	383	Missense	distal	4	no	2.065	2.687	EPSD	COSMIC	2.379	Gain
AGC_NDR_NDR_STK38L_ST	P46937	YAP1	Q9Y2H1	STK38L	S397	D399G	399	Missense	proximal	2	no	7.869	7.746	EPSD	COSMIC	2.379	Down-regulation
AGC_NDR_NDR_STK38L_ST	P46937	YAP1	Q9Y2H1	STK38L	S397	T390I	390	Missense	distal	-7	no	7.869	7.872	EPSD	COSMIC	2.379	Up-regulation
AGC_NDR_NDR_STK38L_ST	P46937	YAP1	Q9Y2H1	STK38L	S397	E396K	396	Missense	proximal	-1	no	7.869	7.806	EPSD	COSMIC	2.379	Down-regulation
AGC_NDR_NDR_STK38L_ST	P46937	YAP1	Q9Y2H1	STK38L	S397	D399H	399	Missense	proximal	2	no	7.869	7.765	EPSD	COSMIC	2.379	Down-regulation
AGC_NDR_NDR_STK38L_ST	P46937	YAP1	Q9Y2H1	STK38L	S397	D395G	395	Missense	proximal	-2	no	7.869	7.659	EPSD	COSMIC	2.379	Down-regulation
AGC_NDR_NDR_STK38L_ST	P46937	YAP1	Q9Y2H1	STK38L	T428	D427H	427	Missense	proximal	-1	no	2.275	2.422	EPSD	COSMIC	2.379	Gain
AGC_NDR_NDR_STK38L_ST	P46937	YAP1	Q9Y2H1	STK38L	S499	L501I	501	Missense	proximal	2	no	2.920	2.917	EPSD	COSMIC	2.379	Down-regulation
AGC_NDR_NDR_STK38L_ST	Q9Y2H1	STK38L	Q9Y2H1	STK38L	T450	P456H	456	Missense	distal	6	no	3.445	3.295	EPSD	COSMIC	2.379	Down-regulation
AGC_NDR_NDR_STK38L_ST	Q9Y2H1	STK38L	Q9Y2H1	STK38L	T457	P456H	456	Missense	proximal	-1	no	2.107	2.599	EPSD	COSMIC	2.379	Gain
CK1_CK1_CK1-D_CSNK1E_ST	O15055	PER2	P49674	CSNK1E	T43	S36N	36	Missense	distal	-7	no	27.802	27.798	EPSD	COSMIC	22.404	Down-regulation
CK1_CK1_CK1-D_CSNK1E_ST	O15055	PER2	P49674	CSNK1E	T43	H41P	41	Missense	proximal	-2	no	27.802	31.205	EPSD	COSMIC	22.404	Up-regulation
CK1_CK1_CK1-D_CSNK1E_ST	O15055	PER2	P49674	CSNK1E	T43	S39N	39	Missense	distal	-4	no	27.802	22.268	EPSD	COSMIC;GDSC;CCLE	22.404	Loss
CK1_CK1_CK1-D_CSNK1E_ST	O15055	PER2	P49674	CSNK1E	T43	E45K	45	Missense	proximal	2	no	27.802	26.444	EPSD	COSMIC	22.404	Down-regulation
CK1_CK1_CK1-D_CSNK1E_ST	O15055	PER2	P49674	CSNK1E	S56	D52G	52	Missense	distal	-4	no	22.846	20.331	EPSD	COSMIC	22.404	Loss
CK1_CK1_CK1-D_CSNK1E_ST	O15055	PER2	P49674	CSNK1E	S56	S53L	53	Missense	distal	-3	no	22.846	19.660	EPSD	COSMIC	22.404	Loss
CK1_CK1_CK1-D_CSNK1E_ST	O15055	PER2	P49674	CSNK1E	S662	S665P	665	Missense	distal	3	no	39.470	38.488	PhosphoSitePlus;EPSD	COSMIC;GDSC;CCLE	22.404	Down-regulation
CK1_CK1_CK1-D_CSNK1E_ST	O15055	PER2	P49674	CSNK1E	S662	S665L	665	Missense	distal	3	no	39.470	32.667	PhosphoSitePlus;EPSD	COSMIC;GDSC;CCLE	22.404	Down-regulation
CK1_CK1_CK1-D_CSNK1E_ST	O15055	PER2	P49674	CSNK1E	S662	P657L	657	Missense	distal	-5	no	39.470	38.827	PhosphoSitePlus;EPSD	COSMIC;CCLE	22.404	Down-regulation
CK1_CK1_CK1-D_CSNK1E_ST	O15055	PER2	P49674	CSNK1E	S662	G658S	658	Missense	distal	-4	no	39.470	43.757	PhosphoSitePlus;EPSD	COSMIC	22.404	Up-regulation
CK1_CK1_CK1-D_CSNK1E_ST	O15055	PER2	P49674	CSNK1E	S662	A655S	655	Missense	distal	-7	no	39.470	39.473	PhosphoSitePlus;EPSD	COSMIC	22.404	Up-regulation
CK1_CK1_CK1-D_CSNK1E_ST	O15055	PER2	P49674	CSNK1E	S665	S665P	665	Missense	central	0	yes	39.530	0.000	EPSD;PhosphoSitePlus	COSMIC;GDSC;CCLE	22.404	Loss
CK1_CK1_CK1-D_CSNK1E_ST	O15055	PER2	P49674	CSNK1E	S665	S665L	665	Missense	central	0	yes	39.530	0.000	EPSD;PhosphoSitePlus	COSMIC;GDSC;CCLE	22.404	Loss
CK1_CK1_CK1-D_CSNK1E_ST	O15055	PER2	P49674	CSNK1E	S665	G658S	658	Missense	distal	-7	no	39.530	39.532	EPSD;PhosphoSitePlus	COSMIC	22.404	Up-regulation
CK1_CK1_CK1-D_CSNK1E_ST	O15055	PER2	P49674	CSNK1E	S668	S665P	665	Missense	distal	-3	no	35.036	35.469	EPSD;PhosphoSitePlus	COSMIC;GDSC;CCLE	22.404	Up-regulation
CK1_CK1_CK1-D_CSNK1E_ST	O15055	PER2	P49674	CSNK1E	S668	S665L	665	Missense	distal	-3	no	35.036	31.850	EPSD;PhosphoSitePlus	COSMIC;GDSC;CCLE	22.404	Down-regulation
CK1_CK1_CK1-D_CSNK1E_ST	O15055	PER2	P49674	CSNK1E	S696	S700F	700	Missense	distal	4	no	23.574	23.691	EPSD	COSMIC	22.404	Up-regulation
CK1_CK1_CK1-D_CSNK1E_ST	O15055	PER2	P49674	CSNK1E	S810	G815R	815	Missense	distal	5	no	25.780	25.662	EPSD	COSMIC	22.404	Down-regulation
CK1_CK1_CK1-D_CSNK1E_ST	O15055	PER2	P49674	CSNK1E	S810	G812R	812	Missense	proximal	2	no	25.780	24.287	EPSD	COSMIC;GDSC	22.404	Down-regulation
CK1_CK1_CK1-D_CSNK1E_ST	O15055	PER2	P49674	CSNK1E	S810	R805Q	805	Missense	distal	-5	no	25.780	26.199	EPSD	COSMIC;GDSC;CCLE	22.404	Up-regulation
CK1_CK1_CK1-D_CSNK1E_ST	O15055	PER2	P49674	CSNK1E	S971	S971L	971	Missense	central	0	yes	24.632	0.000	EPSD	COSMIC	22.404	Loss
CK1_CK1_CK1-D_CSNK1E_ST	O15055	PER2	P49674	CSNK1E	T1013	M1007L	1007	Missense	distal	-6	no	27.830	26.588	EPSD	COSMIC	22.404	Down-regulation
CK1_CK1_CK1-D_CSNK1E_ST	Q92997	DVL3	P49674	CSNK1E	S125	D130Y	130	Missense	distal	5	no	29.683	31.245	EPSD	COSMIC;GDSC;CCLE	22.404	Up-regulation
CK1_CK1_CK1-D_CSNK1E_ST	Q92997	DVL3	P49674	CSNK1E	S125	E127D	127	Missense	proximal	2	no	29.683	27.640	EPSD	COSMIC;GDSC;CCLE	22.404	Down-regulation
CK1_CK1_CK1-D_CSNK1E_ST	Q92997	DVL3	P49674	CSNK1E	S137	D130Y	130	Missense	distal	-7	no	29.116	29.112	EPSD	COSMIC;GDSC;CCLE	22.404	Down-regulation
CK1_CK1_CK1-D_CSNK1E_ST	Q92997	DVL3	P49674	CSNK1E	S137	Q142L	142	Missense	distal	5	no	29.116	30.604	EPSD	COSMIC;GDSC;CCLE	22.404	Up-regulation
CK1_CK1_CK1-D_CSNK1E_ST	Q92997	DVL3	P49674	CSNK1E	S137	R143Q	143	Missense	distal	6	no	29.116	28.052	EPSD	COSMIC	22.404	Down-regulation
CK1_CK1_CK1-D_CSNK1E_ST	Q92997	DVL3	P49674	CSNK1E	S137	T135R	135	Missense	proximal	-2	no	29.116	24.997	EPSD	COSMIC	22.404	Down-regulation
CK1_CK1_CK1-D_CSNK1E_ST	Q92997	DVL3	P49674	CSNK1E	S137	S137Y	137	Missense	central	0	yes	29.116	0.000	EPSD	COSMIC	22.404	Loss
CK1_CK1_CK1-D_CSNK1E_ST	Q92997	DVL3	P49674	CSNK1E	S140	Q142L	142	Missense	proximal	2	no	24.188	22.615	EPSD	COSMIC;GDSC;CCLE	22.404	Down-regulation
CK1_CK1_CK1-D_CSNK1E_ST	Q92997	DVL3	P49674	CSNK1E	S140	R143Q	143	Missense	distal	3	no	24.188	22.755	EPSD	COSMIC	22.404	Down-regulation
CK1_CK1_CK1-D_CSNK1E_ST	Q92997	DVL3	P49674	CSNK1E	S140	T135R	135	Missense	distal	-5	no	24.188	24.119	EPSD	COSMIC	22.404	Down-regulation
CK1_CK1_CK1-D_CSNK1E_ST	Q92997	DVL3	P49674	CSNK1E	S140	S137Y	137	Missense	distal	-3	no	24.188	19.958	EPSD	COSMIC	22.404	Loss
CK1_CK1_CK1-D_CSNK1E_ST	Q92997	DVL3	P49674	CSNK1E	T187	F190S	190	Missense	distal	3	no	21.230	23.758	EPSD	COSMIC	22.404	Gain
CK1_CK1_CK1-D_CSNK1E_ST	Q92997	DVL3	P49674	CSNK1E	S209	R216T	216	Missense	distal	7	no	36.405	36.654	EPSD	COSMIC;GDSC;CCLE	22.404	Up-regulation
CK1_CK1_CK1-D_CSNK1E_ST	Q92997	DVL3	P49674	CSNK1E	S268	S263F	263	Missense	distal	-5	no	23.063	21.343	EPSD	COSMIC	22.404	Loss
CK1_CK1_CK1-D_CSNK1E_ST	Q92997	DVL3	P49674	CSNK1E	S268	G275S	275	Missense	distal	7	no	23.063	22.858	EPSD	COSMIC	22.404	Down-regulation
CK1_CK1_CK1-D_CSNK1E_ST	Q92997	DVL3	P49674	CSNK1E	S421	E427G	427	Missense	distal	6	no	34.827	36.130	EPSD	COSMIC;GDSC;CCLE	22.404	Up-regulation
CK1_CK1_CK1-D_CSNK1E_ST	Q92997	DVL3	P49674	CSNK1E	S421	E423G	423	Missense	proximal	2	no	34.827	33.396	EPSD	COSMIC	22.404	Down-regulation
CK1_CK1_CK1-D_CSNK1E_ST	Q92997	DVL3	P49674	CSNK1E	S421	A420T	420	Missense	proximal	-1	no	34.827	29.052	EPSD	COSMIC	22.404	Down-regulation
CK1_CK1_CK1-D_CSNK1E_ST	Q92997	DVL3	P49674	CSNK1E	S421	V416I	416	Missense	distal	-5	no	34.827	34.429	EPSD	COSMIC;CCLE	22.404	Down-regulation
CK1_CK1_CK1-D_CSNK1E_ST	Q92997	DVL3	P49674	CSNK1E	S421	P422S	422	Missense	proximal	1	no	34.827	35.124	EPSD	COSMIC	22.404	Up-regulation
CK1_CK1_CK1-D_CSNK1E_ST	Q92997	DVL3	P49674	CSNK1E	S516	D519N	519	Missense	distal	3	no	27.900	21.805	EPSD	COSMIC	22.404	Loss
CK1_CK1_CK1-D_CSNK1E_ST	Q92997	DVL3	P49674	CSNK1E	S564	G562E	562	Missense	proximal	-2	no	24.646	23.546	EPSD	COSMIC	22.404	Down-regulation
CK1_CK1_CK1-D_CSNK1E_ST	Q92997	DVL3	P49674	CSNK1E	S564	S564G	564	Missense	central	0	yes	24.646	0.000	EPSD	COSMIC	22.404	Loss
CK1_CK1_CK1-D_CSNK1E_ST	Q92997	DVL3	P49674	CSNK1E	S567	G562E	562	Missense	distal	-5	no	37.739	37.425	EPSD	COSMIC	22.404	Down-regulation
CK1_CK1_CK1-D_CSNK1E_ST	Q92997	DVL3	P49674	CSNK1E	S567	S564G	564	Missense	distal	-3	no	37.739	38.016	EPSD	COSMIC	22.404	Up-regulation
CK1_CK1_CK1-D_CSNK1E_ST	Q92997	DVL3	P49674	CSNK1E	S567	G572C	572	Missense	distal	5	no	37.739	37.399	EPSD	COSMIC	22.404	Down-regulation
CK1_CK1_CK1-D_CSNK1E_ST	Q92997	DVL3	P49674	CSNK1E	S575	R580H	580	Missense	distal	5	no	23.230	22.655	EPSD	COSMIC	22.404	Down-regulation
CK1_CK1_CK1-D_CSNK1E_ST	Q92997	DVL3	P49674	CSNK1E	S575	G577D	577	Missense	proximal	2	no	23.230	22.619	EPSD	COSMIC	22.404	Down-regulation
CK1_CK1_CK1-D_CSNK1E_ST	Q92997	DVL3	P49674	CSNK1E	S575	G572C	572	Missense	distal	-3	no	23.230	19.680	EPSD	COSMIC	22.404	Loss
CK1_CK1_CK1-D_CSNK1E_ST	Q92997	DVL3	P49674	CSNK1E	S578	R580H	580	Missense	proximal	2	no	23.547	24.868	EPSD	COSMIC	22.404	Up-regulation
CK1_CK1_CK1-D_CSNK1E_ST	Q92997	DVL3	P49674	CSNK1E	S578	R585Q	585	Missense	distal	7	no	23.547	23.649	EPSD	COSMIC	22.404	Up-regulation
CK1_CK1_CK1-D_CSNK1E_ST	Q92997	DVL3	P49674	CSNK1E	S578	G577D	577	Missense	proximal	-1	no	23.547	23.038	EPSD	COSMIC	22.404	Down-regulation
CK1_CK1_CK1-D_CSNK1E_ST	Q92997	DVL3	P49674	CSNK1E	S578	G572C	572	Missense	distal	-6	no	23.547	22.939	EPSD	COSMIC	22.404	Down-regulation
CK1_CK1_CK1-D_CSNK1E_ST	Q92997	DVL3	P49674	CSNK1E	S598	P591Q	591	Missense	distal	-7	no	30.566	30.565	EPSD	COSMIC	22.404	Down-regulation
CK1_CK1_CK1-D_CSNK1E_ST	Q92997	DVL3	P49674	CSNK1E	S598	P591S	591	Missense	distal	-7	no	30.566	30.567	EPSD	COSMIC	22.404	Up-regulation
CK1_CK1_CK1-D_CSNK1E_ST	Q92997	DVL3	P49674	CSNK1E	S598	G602S	602	Missense	distal	4	no	30.566	30.456	EPSD	COSMIC	22.404	Down-regulation
CK1_CK1_CK1-D_CSNK1E_ST	Q92997	DVL3	P49674	CSNK1E	S603	G602S	602	Missense	proximal	-1	no	25.535	26.715	EPSD	COSMIC	22.404	Up-regulation
CK1_CK1_CK1-D_CSNK1E_ST	Q92997	DVL3	P49674	CSNK1E	T609	G602S	602	Missense	distal	-7	no	40.225	40.227	EPSD	COSMIC	22.404	Up-regulation
CK1_CK1_CK1-D_CSNK1E_ST	Q92997	DVL3	P49674	CSNK1E	S622	R617Q	617	Missense	distal	-5	no	23.100	23.518	EPSD	COSMIC	22.404	Up-regulation
CK1_CK1_CK1-D_CSNK1E_ST	Q92997	DVL3	P49674	CSNK1E	S622	R624H	624	Missense	proximal	2	no	23.100	24.420	EPSD	COSMIC	22.404	Up-regulation
CK1_CK1_CK1-D_CSNK1E_ST	Q92997	DVL3	P49674	CSNK1E	S697	R702C	702	Missense	distal	5	no	30.413	30.190	EPSD	COSMIC	22.404	Down-regulation
CK1_CK1_CK1-D_CSNK1E_ST	Q92997	DVL3	P49674	CSNK1E	S697	P691L	691	Missense	distal	-6	no	30.413	29.788	EPSD	COSMIC	22.404	Down-regulation
CK1_CK1_CK1-D_CSNK1E_ST	O95863	SNAI1	P49674	CSNK1E	S104	P102S	102	Missense	proximal	-2	no	33.743	35.072	PhosphoSitePlus;EPSD	COSMIC	22.404	Up-regulation
CK1_CK1_CK1-D_CSNK1E_ST	O95863	SNAI1	P49674	CSNK1E	S104	P105Q	105	Missense	proximal	1	no	33.743	32.917	PhosphoSitePlus;EPSD	COSMIC	22.404	Down-regulation
CK1_CK1_CK1-D_CSNK1E_ST	O95863	SNAI1	P49674	CSNK1E	S107	P102S	102	Missense	distal	-5	no	39.045	39.910	EPSD;PhosphoSitePlus	COSMIC	22.404	Up-regulation
CK1_CK1_CK1-D_CSNK1E_ST	O95863	SNAI1	P49674	CSNK1E	S107	P105Q	105	Missense	proximal	-2	no	39.045	34.687	EPSD;PhosphoSitePlus	COSMIC	22.404	Down-regulation
CK1_CK1_CK1-D_CSNK1E_ST	Q8TD43	TRPM4	P49674	CSNK1E	S104	T97M	97	Missense	distal	-7	no	23.239	23.234	EPSD	COSMIC	22.404	Down-regulation
CK1_CK1_CK1-D_CSNK1E_ST	Q8TD43	TRPM4	P49674	CSNK1E	S104	G111D	111	Missense	distal	7	no	23.239	23.195	EPSD	COSMIC	22.404	Down-regulation
CK1_CK1_CK1-D_CSNK1E_ST	Q8TD43	TRPM4	P49674	CSNK1E	S104	A101T	101	Missense	distal	-3	no	23.239	22.857	EPSD	COSMIC	22.404	Down-regulation
CK1_CK1_CK1-D_CSNK1E_ST	Q8TD43	TRPM4	P49674	CSNK1E	S255	R248C	248	Missense	distal	-7	no	22.910	22.913	EPSD	COSMIC	22.404	Up-regulation
CK1_CK1_CK1-D_CSNK1E_ST	Q8TD43	TRPM4	P49674	CSNK1E	S255	R250H	250	Missense	distal	-5	no	22.910	22.288	EPSD	COSMIC	22.404	Loss
CK1_CK1_CK1-D_CSNK1E_ST	Q8TD43	TRPM4	P49674	CSNK1E	S839	A841T	841	Missense	proximal	2	no	36.245	34.417	PhosphoSitePlus	COSMIC	22.404	Down-regulation
CK1_CK1_CK1-D_CSNK1E_ST	Q8TD43	TRPM4	P49674	CSNK1E	S1098	P1101L	1101	Missense	distal	3	no	24.945	19.124	EPSD	COSMIC	22.404	Loss
CK1_CK1_CK1-D_CSNK1E_ST	Q8TD43	TRPM4	P49674	CSNK1E	S1098	R1097Q	1097	Missense	proximal	-1	no	24.945	27.793	EPSD	COSMIC	22.404	Up-regulation
CK1_CK1_CK1-D_CSNK1E_ST	Q8TD43	TRPM4	P49674	CSNK1E	S1102	R1097Q	1097	Missense	distal	-5	no	22.259	22.678	EPSD	COSMIC	22.404	Gain
CK1_CK1_CK1-D_CSNK1E_ST	Q9Y6Q9	NCOA3	P49674	CSNK1E	S214	R218C	218	Missense	distal	4	no	37.141	37.145	EPSD	COSMIC	22.404	Up-regulation
CK1_CK1_CK1-D_CSNK1E_ST	Q9Y6Q9	NCOA3	P49674	CSNK1E	S214	E209K	209	Missense	distal	-5	no	37.141	36.259	EPSD	COSMIC	22.404	Down-regulation
CK1_CK1_CK1-D_CSNK1E_ST	Q9Y6Q9	NCOA3	P49674	CSNK1E	S214	R218H	218	Missense	distal	4	no	37.141	37.102	EPSD	COSMIC	22.404	Down-regulation
CK1_CK1_CK1-D_CSNK1E_ST	Q9Y6Q9	NCOA3	P49674	CSNK1E	S214	M217I	217	Missense	distal	3	no	37.141	33.796	EPSD	COSMIC	22.404	Down-regulation
CK1_CK1_CK1-D_CSNK1E_ST	Q9Y6Q9	NCOA3	P49674	CSNK1E	S214	Y221H	221	Missense	distal	7	no	37.141	36.690	EPSD	COSMIC	22.404	Down-regulation
CK1_CK1_CK1-D_CSNK1E_ST	Q9Y6Q9	NCOA3	P49674	CSNK1E	S214	A213T	213	Missense	proximal	-1	no	37.141	31.366	EPSD	COSMIC;GDSC	22.404	Down-regulation
CK1_CK1_CK1-D_CSNK1E_ST	Q9Y6Q9	NCOA3	P49674	CSNK1E	S214	E209D	209	Missense	distal	-5	no	37.141	36.913	EPSD	COSMIC	22.404	Down-regulation
CK1_CK1_CK1-D_CSNK1E_ST	Q9Y6Q9	NCOA3	P49674	CSNK1E	T282	M289L	289	Missense	distal	7	no	26.682	26.641	EPSD	COSMIC	22.404	Down-regulation
CK1_CK1_CK1-D_CSNK1E_ST	Q9Y6Q9	NCOA3	P49674	CSNK1E	T282	S288F	288	Missense	distal	6	no	26.682	23.477	EPSD	COSMIC	22.404	Down-regulation
CK1_CK1_CK1-D_CSNK1E_ST	Q9Y6Q9	NCOA3	P49674	CSNK1E	T282	R286K	286	Missense	distal	4	no	26.682	26.525	EPSD	COSMIC	22.404	Down-regulation
CK1_CK1_CK1-D_CSNK1E_ST	Q9Y6Q9	NCOA3	P49674	CSNK1E	T282	V277A	277	Missense	distal	-5	no	26.682	26.638	EPSD	COSMIC	22.404	Down-regulation
CK1_CK1_CK1-D_CSNK1E_ST	Q9Y6Q9	NCOA3	P49674	CSNK1E	T282	T282P	282	Missense	central	0	yes	26.682	0.000	EPSD	COSMIC	22.404	Loss
CK1_CK1_CK1-D_CSNK1E_ST	Q9Y6Q9	NCOA3	P49674	CSNK1E	S287	M289L	289	Missense	proximal	2	no	25.354	22.113	EPSD	COSMIC	22.404	Loss
CK1_CK1_CK1-D_CSNK1E_ST	Q9Y6Q9	NCOA3	P49674	CSNK1E	S287	S288F	288	Missense	proximal	1	no	25.354	24.318	EPSD	COSMIC	22.404	Down-regulation
CK1_CK1_CK1-D_CSNK1E_ST	Q9Y6Q9	NCOA3	P49674	CSNK1E	S287	R286K	286	Missense	proximal	-1	no	25.354	28.581	EPSD	COSMIC	22.404	Up-regulation
CK1_CK1_CK1-D_CSNK1E_ST	Q9Y6Q9	NCOA3	P49674	CSNK1E	S287	T282P	282	Missense	distal	-5	no	25.354	25.797	EPSD	COSMIC	22.404	Up-regulation
CK1_CK1_CK1-D_CSNK1E_ST	Q9Y6Q9	NCOA3	P49674	CSNK1E	S288	R286K	286	Missense	proximal	-2	no	21.260	24.177	EPSD	COSMIC	22.404	Gain
CK1_CK1_CK1-D_CSNK1E_ST	Q9Y6Q9	NCOA3	P49674	CSNK1E	T425	Q427H	427	Missense	proximal	2	no	25.196	24.684	EPSD	COSMIC	22.404	Down-regulation
CK1_CK1_CK1-D_CSNK1E_ST	Q9Y6Q9	NCOA3	P49674	CSNK1E	T425	P422A	422	Missense	distal	-3	no	25.196	23.250	EPSD	COSMIC	22.404	Down-regulation
CK1_CK1_CK1-D_CSNK1E_ST	Q9Y6Q9	NCOA3	P49674	CSNK1E	S567	N564S	564	Missense	distal	-3	no	20.191	22.456	EPSD	COSMIC	22.404	Gain
CK1_CK1_CK1-D_CSNK1E_ST	Q9Y6Q9	NCOA3	P49674	CSNK1E	S652	E648K	648	Missense	distal	-4	no	24.559	18.993	EPSD	COSMIC	22.404	Loss
CK1_CK1_CK1-D_CSNK1E_ST	Q9Y6Q9	NCOA3	P49674	CSNK1E	S712	K708T	708	Missense	distal	-4	no	23.305	27.414	EPSD	COSMIC	22.404	Up-regulation
CK1_CK1_CK1-D_CSNK1E_ST	Q9Y6Q9	NCOA3	P49674	CSNK1E	S712	G719E	719	Missense	distal	7	no	23.305	23.283	EPSD	COSMIC	22.404	Down-regulation
CK1_CK1_CK1-D_CSNK1E_ST	Q9Y6Q9	NCOA3	P49674	CSNK1E	S715	K708T	708	Missense	distal	-7	no	25.096	25.098	EPSD	COSMIC	22.404	Up-regulation
CK1_CK1_CK1-D_CSNK1E_ST	Q9Y6Q9	NCOA3	P49674	CSNK1E	S715	G719E	719	Missense	distal	4	no	25.096	25.149	EPSD	COSMIC	22.404	Up-regulation
CK1_CK1_CK1-D_CSNK1E_ST	Q9Y6Q9	NCOA3	P49674	CSNK1E	S771	N764Y	764	Missense	distal	-7	no	22.699	22.697	EPSD	COSMIC	22.404	Down-regulation
CK1_CK1_CK1-D_CSNK1E_ST	Q9Y6Q9	NCOA3	P49674	CSNK1E	S844	S842L	842	Missense	proximal	-2	no	28.117	21.503	EPSD	COSMIC	22.404	Loss
CK1_CK1_CK1-D_CSNK1E_ST	Q9Y6Q9	NCOA3	P49674	CSNK1E	S844	S847C	847	Missense	distal	3	no	28.117	19.025	EPSD	COSMIC	22.404	Loss
CK1_CK1_CK1-D_CSNK1E_ST	Q9Y6Q9	NCOA3	P49674	CSNK1E	S844	P850S	850	Missense	distal	6	no	28.117	27.480	EPSD	COSMIC	22.404	Down-regulation
CK1_CK1_CK1-D_CSNK1E_ST	Q9Y6Q9	NCOA3	P49674	CSNK1E	S916	P923Q	923	Missense	distal	7	no	24.860	25.060	EPSD	COSMIC	22.404	Up-regulation
CK1_CK1_CK1-D_CSNK1E_ST	Q9Y6Q9	NCOA3	P49674	CSNK1E	S916	L922S	922	Missense	distal	6	no	24.860	28.018	EPSD	COSMIC	22.404	Up-regulation
CK1_CK1_CK1-D_CSNK1E_ST	Q9Y6Q9	NCOA3	P49674	CSNK1E	S916	D919V	919	Missense	distal	3	no	24.860	15.489	EPSD	COSMIC	22.404	Loss
CK1_CK1_CK1-D_CSNK1E_ST	Q9Y6Q9	NCOA3	P49674	CSNK1E	S916	W920R	920	Missense	distal	4	no	24.860	24.843	EPSD	COSMIC	22.404	Down-regulation
CK1_CK1_CK1-D_CSNK1E_ST	Q9Y6Q9	NCOA3	P49674	CSNK1E	S917	D919V	919	Missense	proximal	2	no	21.526	23.924	EPSD	COSMIC	22.404	Gain
CK1_CK1_CK1-D_CSNK1E_ST	Q9Y6Q9	NCOA3	P49674	CSNK1E	S917	W920R	920	Missense	distal	3	no	21.526	25.031	EPSD	COSMIC	22.404	Gain
CK1_CK1_CK1-D_CSNK1E_ST	P49674	CSNK1E	P49674	CSNK1E	S368	S363F	363	Missense	distal	-5	no	35.358	33.639	EPSD;PhosphoSitePlus	COSMIC	22.404	Down-regulation
CK1_CK1_CK1-D_CSNK1E_ST	P49674	CSNK1E	P49674	CSNK1E	S368	D371N	371	Missense	distal	3	no	35.358	29.264	EPSD;PhosphoSitePlus	COSMIC	22.404	Down-regulation
CK1_CK1_CK1-D_CSNK1E_ST	P49674	CSNK1E	P49674	CSNK1E	S390	S390F	390	Missense	central	0	yes	23.913	0.000	EPSD	COSMIC	22.404	Loss
CK1_CK1_CK1-D_CSNK1E_ST	P49674	CSNK1E	P49674	CSNK1E	S405	P410L	410	Missense	distal	5	no	24.727	25.719	EPSD;PhosphoSitePlus	COSMIC	22.404	Up-regulation
CK1_CK1_CK1-D_CSNK1E_ST	P49674	CSNK1E	P49674	CSNK1E	S405	P403S	403	Missense	proximal	-2	no	24.727	26.056	EPSD;PhosphoSitePlus	COSMIC	22.404	Up-regulation
CK1_CK1_CK1-D_CSNK1E_ST	O14641	DVL2	P49674	CSNK1E	S155	S155L	155	Missense	central	0	yes	29.945	0.000	EPSD	COSMIC	22.404	Loss
CK1_CK1_CK1-D_CSNK1E_ST	O14641	DVL2	P49674	CSNK1E	S158	S155L	155	Missense	distal	-3	no	29.778	26.592	EPSD	COSMIC	22.404	Down-regulation
CK1_CK1_CK1-D_CSNK1E_ST	O14641	DVL2	P49674	CSNK1E	S195	L198P	198	Missense	distal	3	no	17.959	23.780	EPSD	COSMIC	22.404	Gain
CK1_CK1_CK1-D_CSNK1E_ST	O14641	DVL2	P49674	CSNK1E	S218	T224M	224	Missense	distal	6	no	21.743	24.380	EPSD	COSMIC	22.404	Gain
CK1_CK1_CK1-D_CSNK1E_ST	O14641	DVL2	P49674	CSNK1E	T224	T224M	224	Missense	central	0	yes	32.742	0.000	EPSD;PhosphoSitePlus	COSMIC	22.404	Loss
CK1_CK1_CK1-D_CSNK1E_ST	O14641	DVL2	P49674	CSNK1E	T224	S230F	230	Missense	distal	6	no	32.742	29.536	EPSD;PhosphoSitePlus	COSMIC	22.404	Down-regulation
CK1_CK1_CK1-D_CSNK1E_ST	O14641	DVL2	P49674	CSNK1E	T224	R231Q	231	Missense	distal	7	no	32.742	32.844	EPSD;PhosphoSitePlus	COSMIC	22.404	Up-regulation
CK1_CK1_CK1-D_CSNK1E_ST	O14641	DVL2	P49674	CSNK1E	S227	T224M	224	Missense	distal	-3	no	26.666	27.547	EPSD	COSMIC	22.404	Up-regulation
CK1_CK1_CK1-D_CSNK1E_ST	O14641	DVL2	P49674	CSNK1E	S227	S230F	230	Missense	distal	3	no	26.666	24.138	EPSD	COSMIC	22.404	Down-regulation
CK1_CK1_CK1-D_CSNK1E_ST	O14641	DVL2	P49674	CSNK1E	S227	L233R	233	Missense	distal	6	no	26.666	29.999	EPSD	COSMIC	22.404	Up-regulation
CK1_CK1_CK1-D_CSNK1E_ST	O14641	DVL2	P49674	CSNK1E	S227	R231Q	231	Missense	distal	4	no	26.666	26.669	EPSD	COSMIC	22.404	Up-regulation
CK1_CK1_CK1-D_CSNK1E_ST	O14641	DVL2	P49674	CSNK1E	S228	T224M	224	Missense	distal	-4	no	35.464	34.905	EPSD	COSMIC	22.404	Down-regulation
CK1_CK1_CK1-D_CSNK1E_ST	O14641	DVL2	P49674	CSNK1E	S228	S230F	230	Missense	proximal	2	no	35.464	34.276	EPSD	COSMIC	22.404	Down-regulation
CK1_CK1_CK1-D_CSNK1E_ST	O14641	DVL2	P49674	CSNK1E	S228	L233R	233	Missense	distal	5	no	35.464	35.508	EPSD	COSMIC	22.404	Up-regulation
CK1_CK1_CK1-D_CSNK1E_ST	O14641	DVL2	P49674	CSNK1E	S228	R235C	235	Missense	distal	7	no	35.464	35.526	EPSD	COSMIC	22.404	Up-regulation
CK1_CK1_CK1-D_CSNK1E_ST	O14641	DVL2	P49674	CSNK1E	S228	R231Q	231	Missense	distal	3	no	35.464	34.030	EPSD	COSMIC	22.404	Down-regulation
CK1_CK1_CK1-D_CSNK1E_ST	O14641	DVL2	P49674	CSNK1E	S230	L233R	233	Missense	distal	3	no	19.676	24.435	EPSD	COSMIC	22.404	Gain
CK1_CK1_CK1-D_CSNK1E_ST	O14641	DVL2	P49674	CSNK1E	S286	I282T	282	Missense	distal	-4	no	24.069	26.766	EPSD	COSMIC	22.404	Up-regulation
CK1_CK1_CK1-D_CSNK1E_ST	O14641	DVL2	P49674	CSNK1E	S404	D410H	410	Missense	distal	6	no	31.747	29.878	EPSD	COSMIC	22.404	Down-regulation
CK1_CK1_CK1-D_CSNK1E_ST	O14641	DVL2	P49674	CSNK1E	S407	D410H	410	Missense	distal	3	no	23.280	14.115	EPSD	COSMIC	22.404	Loss
CK1_CK1_CK1-D_CSNK1E_ST	O14641	DVL2	P49674	CSNK1E	S580	T575N	575	Missense	distal	-5	no	26.817	26.996	EPSD	COSMIC	22.404	Up-regulation
CK1_CK1_CK1-D_CSNK1E_ST	O14641	DVL2	P49674	CSNK1E	S614	G617S	617	Missense	distal	3	no	20.603	23.305	EPSD	COSMIC;GDSC;CCLE	22.404	Gain
CK1_CK1_CK1-D_CSNK1E_ST	O14641	DVL2	P49674	CSNK1E	S616	G617S	617	Missense	proximal	1	no	25.336	26.315	EPSD	COSMIC;GDSC;CCLE	22.404	Up-regulation
CK1_CK1_CK1-D_CSNK1E_ST	O14641	DVL2	P49674	CSNK1E	S618	G617S	617	Missense	proximal	-1	no	31.832	33.011	EPSD	COSMIC;GDSC;CCLE	22.404	Up-regulation
CK1_CK1_CK1-D_CSNK1E_ST	O14641	DVL2	P49674	CSNK1E	S618	S625P	625	Missense	distal	7	no	31.832	32.036	EPSD	COSMIC	22.404	Up-regulation
CK1_CK1_CK1-D_CSNK1E_ST	O14641	DVL2	P49674	CSNK1E	S618	P624L	624	Missense	distal	6	no	31.832	28.036	EPSD	COSMIC	22.404	Down-regulation
CK1_CK1_CK1-D_CSNK1E_ST	O14641	DVL2	P49674	CSNK1E	S620	R627Q	627	Missense	distal	7	no	24.754	24.856	EPSD	COSMIC	22.404	Up-regulation
CK1_CK1_CK1-D_CSNK1E_ST	O14641	DVL2	P49674	CSNK1E	S620	G617S	617	Missense	distal	-3	no	24.754	24.478	EPSD	COSMIC;GDSC;CCLE	22.404	Down-regulation
CK1_CK1_CK1-D_CSNK1E_ST	O14641	DVL2	P49674	CSNK1E	S620	S625P	625	Missense	distal	5	no	24.754	25.047	EPSD	COSMIC	22.404	Up-regulation
CK1_CK1_CK1-D_CSNK1E_ST	O14641	DVL2	P49674	CSNK1E	S620	P624L	624	Missense	distal	4	no	24.754	24.864	EPSD	COSMIC	22.404	Up-regulation
CK1_CK1_CK1-D_CSNK1E_ST	O14641	DVL2	P49674	CSNK1E	S622	R627Q	627	Missense	distal	5	no	39.245	37.714	EPSD	COSMIC	22.404	Down-regulation
CK1_CK1_CK1-D_CSNK1E_ST	O14641	DVL2	P49674	CSNK1E	S622	G617S	617	Missense	distal	-5	no	39.245	39.612	EPSD	COSMIC;GDSC;CCLE	22.404	Up-regulation
CK1_CK1_CK1-D_CSNK1E_ST	O14641	DVL2	P49674	CSNK1E	S622	S625P	625	Missense	distal	3	no	39.245	38.263	EPSD	COSMIC	22.404	Down-regulation
CK1_CK1_CK1-D_CSNK1E_ST	O14641	DVL2	P49674	CSNK1E	S622	P624L	624	Missense	proximal	2	no	39.245	38.295	EPSD	COSMIC	22.404	Down-regulation
CK1_CK1_CK1-D_CSNK1E_ST	O14641	DVL2	P49674	CSNK1E	S626	R627Q	627	Missense	proximal	1	no	33.690	33.301	EPSD	COSMIC	22.404	Down-regulation
CK1_CK1_CK1-D_CSNK1E_ST	O14641	DVL2	P49674	CSNK1E	S626	S625P	625	Missense	proximal	-1	no	33.690	32.786	EPSD	COSMIC	22.404	Down-regulation
CK1_CK1_CK1-D_CSNK1E_ST	O14641	DVL2	P49674	CSNK1E	S626	S630N	630	Missense	distal	4	no	33.690	33.782	EPSD	COSMIC	22.404	Up-regulation
CK1_CK1_CK1-D_CSNK1E_ST	O14641	DVL2	P49674	CSNK1E	S626	P624L	624	Missense	proximal	-2	no	33.690	28.405	EPSD	COSMIC	22.404	Down-regulation
CK1_CK1_CK1-D_CSNK1E_ST	O14641	DVL2	P49674	CSNK1E	S630	R627Q	627	Missense	distal	-3	no	25.061	24.900	EPSD	COSMIC	22.404	Down-regulation
CK1_CK1_CK1-D_CSNK1E_ST	O14641	DVL2	P49674	CSNK1E	S630	S625P	625	Missense	distal	-5	no	25.061	24.196	EPSD	COSMIC	22.404	Down-regulation
CK1_CK1_CK1-D_CSNK1E_ST	O14641	DVL2	P49674	CSNK1E	S630	S630N	630	Missense	central	0	yes	25.061	0.000	EPSD	COSMIC	22.404	Loss
CK1_CK1_CK1-D_CSNK1E_ST	O14641	DVL2	P49674	CSNK1E	S630	P624L	624	Missense	distal	-6	no	25.061	24.436	EPSD	COSMIC	22.404	Down-regulation
CK1_CK1_CK1-D_CSNK1E_ST	O14641	DVL2	P49674	CSNK1E	T652	L658P	658	Missense	distal	6	no	25.567	29.362	EPSD	COSMIC	22.404	Up-regulation
CK1_CK1_CK1-D_CSNK1E_ST	Q13148	TARDBP	P49674	CSNK1E	T88	D86Y	86	Missense	proximal	-2	no	24.176	22.674	EPSD	COSMIC	22.404	Down-regulation
CK1_CK1_CK1-D_CSNK1E_ST	Q13148	TARDBP	P49674	CSNK1E	T88	N81D	81	Missense	distal	-7	no	24.176	24.178	EPSD	COSMIC;GDSC;CCLE	22.404	Up-regulation
CK1_CK1_CK1-D_CSNK1E_ST	Q13148	TARDBP	P49674	CSNK1E	T88	M85V	85	Missense	distal	-3	no	24.176	22.192	EPSD	COSMIC	22.404	Loss
CK1_CK1_CK1-D_CSNK1E_ST	Q13148	TARDBP	P49674	CSNK1E	S91	D86Y	86	Missense	distal	-5	no	22.843	22.067	EPSD	COSMIC	22.404	Loss
CK1_CK1_CK1-D_CSNK1E_ST	Q13148	TARDBP	P49674	CSNK1E	S91	M85V	85	Missense	distal	-6	no	22.843	21.484	EPSD	COSMIC	22.404	Loss
CK1_CK1_CK1-D_CSNK1E_ST	Q13148	TARDBP	P49674	CSNK1E	S92	D86Y	86	Missense	distal	-6	no	27.727	27.645	EPSD	COSMIC	22.404	Down-regulation
CK1_CK1_CK1-D_CSNK1E_ST	Q13148	TARDBP	P49674	CSNK1E	S92	M85V	85	Missense	distal	-7	no	27.727	27.728	EPSD	COSMIC	22.404	Up-regulation
CK1_CK1_CK1-D_CSNK1E_ST	Q13148	TARDBP	P49674	CSNK1E	S242	L248S	248	Missense	distal	6	no	19.585	22.743	EPSD	COSMIC	22.404	Gain
CK1_CK1_CK1-D_CSNK1E_ST	Q13148	TARDBP	P49674	CSNK1E	S375	G368C	368	Missense	distal	-7	no	22.809	22.807	EPSD	COSMIC	22.404	Down-regulation
CK1_CK1_CK1-D_CSNK1E_ST	Q13148	TARDBP	P49674	CSNK1E	S389	N390D	390	Missense	proximal	1	no	25.241	25.075	EPSD	COSMIC	22.404	Down-regulation
CK1_CK1_CK1-D_CSNK1E_ST	O75581	LRP6	P49674	CSNK1E	S1444	S1447N	1447	Missense	distal	3	no	30.982	25.673	EPSD	COSMIC	22.404	Down-regulation
CK1_CK1_CK1-D_CSNK1E_ST	O75581	LRP6	P49674	CSNK1E	S1455	P1458L	1458	Missense	distal	3	no	23.599	17.778	EPSD	COSMIC;GDSC	22.404	Loss
CK1_CK1_CK1-D_CSNK1E_ST	O75581	LRP6	P49674	CSNK1E	S1455	P1459L	1459	Missense	distal	4	no	23.599	23.709	EPSD	COSMIC	22.404	Up-regulation
CK1_CK1_CK1-D_CSNK1E_ST	O75581	LRP6	P49674	CSNK1E	S1455	P1458S	1458	Missense	distal	3	no	23.599	24.581	EPSD	COSMIC;GDSC	22.404	Up-regulation
CK1_CK1_CK1-D_CSNK1E_ST	O75581	LRP6	P49674	CSNK1E	T1466	A1463V	1463	Missense	distal	-3	no	23.177	21.693	EPSD	COSMIC;GDSC;CCLE	22.404	Loss
CK1_CK1_CK1-D_CSNK1E_ST	O75581	LRP6	P49674	CSNK1E	T1466	P1459L	1459	Missense	distal	-7	no	23.177	23.173	EPSD	COSMIC	22.404	Down-regulation
CK1_CK1_CK1-D_CSNK1E_ST	O75581	LRP6	P49674	CSNK1E	T1466	H1464Y	1464	Missense	proximal	-2	no	23.177	22.375	EPSD	COSMIC	22.404	Loss
CK1_CK1_CK1-D_CSNK1E_ST	O75581	LRP6	P49674	CSNK1E	T1466	S1469A	1469	Missense	distal	3	no	23.177	17.017	EPSD	COSMIC	22.404	Loss
CK1_CK1_CK1-D_CSNK1E_ST	O75581	LRP6	P49674	CSNK1E	S1469	A1463V	1463	Missense	distal	-6	no	30.665	29.951	EPSD	COSMIC;GDSC;CCLE	22.404	Down-regulation
CK1_CK1_CK1-D_CSNK1E_ST	O75581	LRP6	P49674	CSNK1E	S1469	H1464Y	1464	Missense	distal	-5	no	30.665	30.979	EPSD	COSMIC	22.404	Up-regulation
CK1_CK1_CK1-D_CSNK1E_ST	O75581	LRP6	P49674	CSNK1E	S1469	S1469A	1469	Missense	central	0	yes	30.665	0.000	EPSD	COSMIC	22.404	Loss
CK1_CK1_CK1-D_CSNK1E_ST	O75581	LRP6	P49674	CSNK1E	S1472	S1469A	1469	Missense	distal	-3	no	35.188	33.676	EPSD	COSMIC	22.404	Down-regulation
CK1_CK1_CK1-D_CSNK1E_ST	O75581	LRP6	P49674	CSNK1E	T1476	S1469A	1469	Missense	distal	-7	no	25.298	25.295	EPSD	COSMIC	22.404	Down-regulation
CK1_CK1_CK1-D_CSNK1E_ST	O75581	LRP6	P49674	CSNK1E	S1544	R1545L	1545	Missense	proximal	1	no	23.885	23.966	EPSD	COSMIC	22.404	Up-regulation
CK1_CK1_CK1-D_CSNK1E_ST	O75581	LRP6	P49674	CSNK1E	S1544	A1542G	1542	Missense	proximal	-2	no	23.885	20.825	EPSD	COSMIC	22.404	Loss
CK1_CK1_CK1-D_CSNK1E_ST	O75581	LRP6	P49674	CSNK1E	S1544	P1543S	1543	Missense	proximal	-1	no	23.885	24.789	EPSD	COSMIC	22.404	Up-regulation
CK1_CK1_CK1-D_CSNK1E_ST	P12830	CDH1	P49674	CSNK1E	T576	L581P	581	Missense	distal	5	no	32.821	31.829	EPSD	COSMIC	22.404	Down-regulation
CK1_CK1_CK1-D_CSNK1E_ST	P12830	CDH1	P49674	CSNK1E	T576	G571S	571	Missense	distal	-5	no	32.821	33.188	EPSD	COSMIC	22.404	Up-regulation
CK1_CK1_CK1-D_CSNK1E_ST	P12830	CDH1	P49674	CSNK1E	T576	N570S	570	Missense	distal	-6	no	32.821	33.254	EPSD	COSMIC	22.404	Up-regulation
CK1_CK1_CK1-D_CSNK1E_ST	P12830	CDH1	P49674	CSNK1E	T576	P573S	573	Missense	distal	-3	no	32.821	32.388	EPSD	COSMIC	22.404	Down-regulation
CK1_CK1_CK1-D_CSNK1E_ST	P12830	CDH1	P49674	CSNK1E	S844	S838G	838	Missense	distal	-6	no	39.355	38.270	PhosphoSitePlus	COSMIC	22.404	Down-regulation
CK1_CK1_CK1-D_CSNK1E_ST	P12830	CDH1	P49674	CSNK1E	S844	S847F	847	Missense	distal	3	no	39.355	36.828	PhosphoSitePlus	COSMIC	22.404	Down-regulation
CK1_CK1_CK1-D_CSNK1E_ST	P12830	CDH1	P49674	CSNK1E	S844	S838I	838	Missense	distal	-6	no	39.355	39.530	PhosphoSitePlus	COSMIC	22.404	Up-regulation
CK1_CK1_CK1-D_CSNK1E_ST	P12830	CDH1	P49674	CSNK1E	S844	A842V	842	Missense	proximal	-2	no	39.355	37.369	PhosphoSitePlus	COSMIC	22.404	Down-regulation
CK1_CK1_CK1-D_CSNK1E_ST	P12830	CDH1	P49674	CSNK1E	S844	S846T	846	Missense	proximal	2	no	39.355	40.190	PhosphoSitePlus	COSMIC	22.404	Up-regulation
CK1_CK1_CK1-D_CSNK1E_ST	P12830	CDH1	P49674	CSNK1E	S844	L845V	845	Missense	proximal	1	no	39.355	39.691	PhosphoSitePlus	COSMIC	22.404	Up-regulation
CK1_CK1_CK1-D_CSNK1E_ST	P12830	CDH1	P49674	CSNK1E	S844	S840F	840	Missense	distal	-4	no	39.355	34.233	PhosphoSitePlus	COSMIC	22.404	Down-regulation
CK1_CK1_CK1-D_CSNK1E_ST	P12830	CDH1	P49674	CSNK1E	S844	S851L	851	Missense	distal	7	no	39.355	39.944	PhosphoSitePlus	COSMIC	22.404	Up-regulation
CK1_CK1_CK1-D_CSNK1E_ST	P12830	CDH1	P49674	CSNK1E	S847	E852D	852	Missense	distal	5	no	27.367	27.236	EPSD	COSMIC	22.404	Down-regulation
CK1_CK1_CK1-D_CSNK1E_ST	P12830	CDH1	P49674	CSNK1E	S847	S853P	853	Missense	distal	6	no	27.367	28.005	EPSD	COSMIC	22.404	Up-regulation
CK1_CK1_CK1-D_CSNK1E_ST	P12830	CDH1	P49674	CSNK1E	S847	D854Y	854	Missense	distal	7	no	27.367	28.092	EPSD	COSMIC	22.404	Up-regulation
CK1_CK1_CK1-D_CSNK1E_ST	P12830	CDH1	P49674	CSNK1E	S847	S847F	847	Missense	central	0	yes	27.367	0.000	EPSD	COSMIC	22.404	Loss
CK1_CK1_CK1-D_CSNK1E_ST	P12830	CDH1	P49674	CSNK1E	S847	A842V	842	Missense	distal	-5	no	27.367	27.412	EPSD	COSMIC	22.404	Up-regulation
CK1_CK1_CK1-D_CSNK1E_ST	P12830	CDH1	P49674	CSNK1E	S847	E852K	852	Missense	distal	5	no	27.367	27.430	EPSD	COSMIC	22.404	Up-regulation
CK1_CK1_CK1-D_CSNK1E_ST	P12830	CDH1	P49674	CSNK1E	S847	S846T	846	Missense	proximal	-1	no	27.367	25.267	EPSD	COSMIC	22.404	Down-regulation
CK1_CK1_CK1-D_CSNK1E_ST	P12830	CDH1	P49674	CSNK1E	S847	L845V	845	Missense	proximal	-2	no	27.367	32.854	EPSD	COSMIC	22.404	Up-regulation
CK1_CK1_CK1-D_CSNK1E_ST	P12830	CDH1	P49674	CSNK1E	S847	S840F	840	Missense	distal	-7	no	27.367	27.363	EPSD	COSMIC	22.404	Down-regulation
CK1_CK1_CK1-D_CSNK1E_ST	P12830	CDH1	P49674	CSNK1E	S847	S851L	851	Missense	distal	4	no	27.367	27.511	EPSD	COSMIC	22.404	Up-regulation
CK1_CK1_CK1-D_CSNK1E_ST	P12830	CDH1	P49674	CSNK1E	S850	L845V	845	Missense	distal	-5	no	21.848	22.756	EPSD	COSMIC	22.404	Gain
CK1_CK1_CK1-D_CSNK1E_ST	P12830	CDH1	P49674	CSNK1E	S851	D858E	858	Missense	distal	7	no	29.793	29.816	EPSD	COSMIC	22.404	Up-regulation
CK1_CK1_CK1-D_CSNK1E_ST	P12830	CDH1	P49674	CSNK1E	S851	E852D	852	Missense	proximal	1	no	29.793	29.932	EPSD	COSMIC	22.404	Up-regulation
CK1_CK1_CK1-D_CSNK1E_ST	P12830	CDH1	P49674	CSNK1E	S851	S853P	853	Missense	proximal	2	no	29.793	28.218	EPSD	COSMIC	22.404	Down-regulation
CK1_CK1_CK1-D_CSNK1E_ST	P12830	CDH1	P49674	CSNK1E	S851	D854Y	854	Missense	distal	3	no	29.793	19.137	EPSD	COSMIC	22.404	Loss
CK1_CK1_CK1-D_CSNK1E_ST	P12830	CDH1	P49674	CSNK1E	S851	S847F	847	Missense	distal	-4	no	29.793	24.671	EPSD	COSMIC	22.404	Down-regulation
CK1_CK1_CK1-D_CSNK1E_ST	P12830	CDH1	P49674	CSNK1E	S851	E852K	852	Missense	proximal	1	no	29.793	29.904	EPSD	COSMIC	22.404	Up-regulation
CK1_CK1_CK1-D_CSNK1E_ST	P12830	CDH1	P49674	CSNK1E	S851	S846T	846	Missense	distal	-5	no	29.793	28.485	EPSD	COSMIC	22.404	Down-regulation
CK1_CK1_CK1-D_CSNK1E_ST	P12830	CDH1	P49674	CSNK1E	S851	L845V	845	Missense	distal	-6	no	29.793	29.676	EPSD	COSMIC	22.404	Down-regulation
CK1_CK1_CK1-D_CSNK1E_ST	P12830	CDH1	P49674	CSNK1E	S851	Q857K	857	Missense	distal	6	no	29.793	28.554	EPSD	COSMIC	22.404	Down-regulation
CK1_CK1_CK1-D_CSNK1E_ST	P12830	CDH1	P49674	CSNK1E	S851	S851L	851	Missense	central	0	yes	29.793	0.000	EPSD	COSMIC	22.404	Loss
CK1_CK1_CK1-D_CSNK1E_ST	P12830	CDH1	P49674	CSNK1E	S853	D858E	858	Missense	distal	5	no	33.379	33.510	EPSD	COSMIC	22.404	Up-regulation
CK1_CK1_CK1-D_CSNK1E_ST	P12830	CDH1	P49674	CSNK1E	S853	E852D	852	Missense	proximal	-1	no	33.379	31.217	EPSD	COSMIC	22.404	Down-regulation
CK1_CK1_CK1-D_CSNK1E_ST	P12830	CDH1	P49674	CSNK1E	S853	S853P	853	Missense	central	0	yes	33.379	0.000	EPSD	COSMIC	22.404	Loss
CK1_CK1_CK1-D_CSNK1E_ST	P12830	CDH1	P49674	CSNK1E	S853	D854Y	854	Missense	proximal	1	no	33.379	32.979	EPSD	COSMIC	22.404	Down-regulation
CK1_CK1_CK1-D_CSNK1E_ST	P12830	CDH1	P49674	CSNK1E	S853	Y859C	859	Missense	distal	6	no	33.379	32.445	EPSD	COSMIC	22.404	Down-regulation
CK1_CK1_CK1-D_CSNK1E_ST	P12830	CDH1	P49674	CSNK1E	S853	S847F	847	Missense	distal	-6	no	33.379	32.229	EPSD	COSMIC	22.404	Down-regulation
CK1_CK1_CK1-D_CSNK1E_ST	P12830	CDH1	P49674	CSNK1E	S853	E852K	852	Missense	proximal	-1	no	33.379	29.872	EPSD	COSMIC	22.404	Down-regulation
CK1_CK1_CK1-D_CSNK1E_ST	P12830	CDH1	P49674	CSNK1E	S853	S846T	846	Missense	distal	-7	no	33.379	33.380	EPSD	COSMIC	22.404	Up-regulation
CK1_CK1_CK1-D_CSNK1E_ST	P12830	CDH1	P49674	CSNK1E	S853	Q857K	857	Missense	distal	4	no	33.379	33.219	EPSD	COSMIC	22.404	Down-regulation
CK1_CK1_CK1-D_CSNK1E_ST	P12830	CDH1	P49674	CSNK1E	S853	S851L	851	Missense	proximal	-2	no	33.379	26.764	EPSD	COSMIC	22.404	Down-regulation
CK1_CK1_CK1-D_CSNK1E_ST	Q13114	TRAF3	P49674	CSNK1E	S349	S352N	352	Missense	distal	3	no	37.747	32.437	PhosphoSitePlus	COSMIC;CCLE	22.404	Down-regulation
CK1_CK1_CK1-D_CSNK1E_ST	P25054	APC	P49674	CSNK1E	S5	A4S	4	Missense	proximal	-1	no	23.043	19.368	EPSD	COSMIC	22.404	Loss
CK1_CK1_CK1-D_CSNK1E_ST	P25054	APC	P49674	CSNK1E	S5	D7N	7	Missense	proximal	2	no	23.043	23.671	EPSD	COSMIC	22.404	Up-regulation
CK1_CK1_CK1-D_CSNK1E_ST	P25054	APC	P49674	CSNK1E	T39	K45R	45	Missense	distal	6	no	32.352	34.656	EPSD	COSMIC	22.404	Up-regulation
CK1_CK1_CK1-D_CSNK1E_ST	P25054	APC	P49674	CSNK1E	T39	L34F	34	Missense	distal	-5	no	32.352	32.141	EPSD	COSMIC	22.404	Down-regulation
CK1_CK1_CK1-D_CSNK1E_ST	P25054	APC	P49674	CSNK1E	T39	N32S	32	Missense	distal	-7	no	32.352	32.356	EPSD	COSMIC	22.404	Up-regulation
CK1_CK1_CK1-D_CSNK1E_ST	P25054	APC	P49674	CSNK1E	T39	L34R	34	Missense	distal	-5	no	32.352	32.482	EPSD	COSMIC	22.404	Up-regulation
CK1_CK1_CK1-D_CSNK1E_ST	P25054	APC	P49674	CSNK1E	T39	M44I	44	Missense	distal	5	no	32.352	33.136	EPSD	COSMIC	22.404	Up-regulation
CK1_CK1_CK1-D_CSNK1E_ST	P25054	APC	P49674	CSNK1E	T39	H33N	33	Missense	distal	-6	no	32.352	32.561	EPSD	COSMIC	22.404	Up-regulation
CK1_CK1_CK1-D_CSNK1E_ST	P25054	APC	P49674	CSNK1E	S62	A59G	59	Missense	distal	-3	no	22.018	23.806	EPSD	COSMIC	22.404	Gain
CK1_CK1_CK1-D_CSNK1E_ST	P25054	APC	P49674	CSNK1E	S102	S95F	95	Missense	distal	-7	no	29.973	29.969	EPSD	COSMIC	22.404	Down-regulation
CK1_CK1_CK1-D_CSNK1E_ST	P25054	APC	P49674	CSNK1E	S102	R99W	99	Missense	distal	-3	no	29.973	28.640	EPSD	COSMIC	22.404	Down-regulation
CK1_CK1_CK1-D_CSNK1E_ST	P25054	APC	P49674	CSNK1E	S102	S105G	105	Missense	distal	3	no	29.973	27.271	EPSD	COSMIC	22.404	Down-regulation
CK1_CK1_CK1-D_CSNK1E_ST	P25054	APC	P49674	CSNK1E	S111	M115I	115	Missense	distal	4	no	23.480	23.436	EPSD	COSMIC	22.404	Down-regulation
CK1_CK1_CK1-D_CSNK1E_ST	P25054	APC	P49674	CSNK1E	S111	C110Y	110	Missense	proximal	-1	no	23.480	24.724	EPSD	COSMIC	22.404	Up-regulation
CK1_CK1_CK1-D_CSNK1E_ST	P25054	APC	P49674	CSNK1E	S111	S117L	117	Missense	distal	6	no	23.480	20.323	EPSD	COSMIC	22.404	Loss
CK1_CK1_CK1-D_CSNK1E_ST	P25054	APC	P49674	CSNK1E	S111	S105G	105	Missense	distal	-6	no	23.480	22.394	EPSD	COSMIC	22.404	Loss
CK1_CK1_CK1-D_CSNK1E_ST	P25054	APC	P49674	CSNK1E	S117	P119A	119	Missense	proximal	2	no	20.865	25.102	EPSD	COSMIC	22.404	Gain
CK1_CK1_CK1-D_CSNK1E_ST	P25054	APC	P49674	CSNK1E	S117	M115I	115	Missense	proximal	-2	no	20.865	23.502	EPSD	COSMIC	22.404	Gain
CK1_CK1_CK1-D_CSNK1E_ST	P25054	APC	P49674	CSNK1E	S290	M284I	284	Missense	distal	-6	no	32.387	32.601	EPSD	COSMIC	22.404	Up-regulation
CK1_CK1_CK1-D_CSNK1E_ST	P25054	APC	P49674	CSNK1E	S290	R283L	283	Missense	distal	-7	no	32.387	32.388	EPSD	COSMIC	22.404	Up-regulation
CK1_CK1_CK1-D_CSNK1E_ST	P25054	APC	P49674	CSNK1E	S290	V291F	291	Missense	proximal	1	no	32.387	31.667	EPSD	COSMIC	22.404	Down-regulation
CK1_CK1_CK1-D_CSNK1E_ST	P25054	APC	P49674	CSNK1E	S290	D285N	285	Missense	distal	-5	no	32.387	32.167	EPSD	COSMIC	22.404	Down-regulation
CK1_CK1_CK1-D_CSNK1E_ST	P25054	APC	P49674	CSNK1E	S290	L292F	292	Missense	proximal	2	no	32.387	33.725	EPSD	COSMIC	22.404	Up-regulation
CK1_CK1_CK1-D_CSNK1E_ST	P25054	APC	P49674	CSNK1E	S290	T297A	297	Missense	distal	7	no	32.387	32.279	EPSD	COSMIC	22.404	Down-regulation
CK1_CK1_CK1-D_CSNK1E_ST	P25054	APC	P49674	CSNK1E	S293	V291F	291	Missense	proximal	-2	no	26.270	19.360	EPSD	COSMIC	22.404	Loss
CK1_CK1_CK1-D_CSNK1E_ST	P25054	APC	P49674	CSNK1E	S293	L292F	292	Missense	proximal	-1	no	26.270	26.870	EPSD	COSMIC	22.404	Up-regulation
CK1_CK1_CK1-D_CSNK1E_ST	P25054	APC	P49674	CSNK1E	S293	T297A	297	Missense	distal	4	no	26.270	26.241	EPSD	COSMIC	22.404	Down-regulation
CK1_CK1_CK1-D_CSNK1E_ST	P25054	APC	P49674	CSNK1E	S296	V291F	291	Missense	distal	-5	no	24.861	23.742	EPSD	COSMIC	22.404	Down-regulation
CK1_CK1_CK1-D_CSNK1E_ST	P25054	APC	P49674	CSNK1E	S296	R303K	303	Missense	distal	7	no	24.861	25.098	EPSD	COSMIC	22.404	Up-regulation
CK1_CK1_CK1-D_CSNK1E_ST	P25054	APC	P49674	CSNK1E	S296	P301L	301	Missense	distal	5	no	24.861	25.853	EPSD	COSMIC	22.404	Up-regulation
CK1_CK1_CK1-D_CSNK1E_ST	P25054	APC	P49674	CSNK1E	S296	L292F	292	Missense	distal	-4	no	24.861	28.031	EPSD	COSMIC	22.404	Up-regulation
CK1_CK1_CK1-D_CSNK1E_ST	P25054	APC	P49674	CSNK1E	S296	T297A	297	Missense	proximal	1	no	24.861	25.184	EPSD	COSMIC	22.404	Up-regulation
CK1_CK1_CK1-D_CSNK1E_ST	P25054	APC	P49674	CSNK1E	S299	T305R	305	Missense	distal	6	no	19.829	24.590	EPSD	COSMIC	22.404	Gain
CK1_CK1_CK1-D_CSNK1E_ST	P25054	APC	P49674	CSNK1E	S299	T297A	297	Missense	proximal	-2	no	19.829	23.477	EPSD	COSMIC	22.404	Gain
CK1_CK1_CK1-D_CSNK1E_ST	P25054	APC	P49674	CSNK1E	S747	L749F	749	Missense	proximal	2	no	32.569	33.906	EPSD	COSMIC	22.404	Up-regulation
CK1_CK1_CK1-D_CSNK1E_ST	P25054	APC	P49674	CSNK1E	S747	H753R	753	Missense	distal	6	no	32.569	34.801	EPSD	COSMIC	22.404	Up-regulation
CK1_CK1_CK1-D_CSNK1E_ST	P25054	APC	P49674	CSNK1E	S747	S744F	744	Missense	distal	-3	no	32.569	30.133	EPSD	COSMIC	22.404	Down-regulation
CK1_CK1_CK1-D_CSNK1E_ST	P25054	APC	P49674	CSNK1E	S747	P745R	745	Missense	proximal	-2	no	32.569	26.990	EPSD	COSMIC	22.404	Down-regulation
CK1_CK1_CK1-D_CSNK1E_ST	P25054	APC	P49674	CSNK1E	T899	A896S	896	Missense	distal	-3	no	22.179	23.691	EPSD	COSMIC	22.404	Gain
CK1_CK1_CK1-D_CSNK1E_ST	P25054	APC	P49674	CSNK1E	T899	S906F	906	Missense	distal	7	no	22.179	22.913	EPSD	COSMIC	22.404	Gain
CK1_CK1_CK1-D_CSNK1E_ST	P25054	APC	P49674	CSNK1E	T899	E893K	893	Missense	distal	-6	no	22.179	24.311	EPSD	COSMIC	22.404	Gain
CK1_CK1_CK1-D_CSNK1E_ST	P25054	APC	P49674	CSNK1E	T899	V894M	894	Missense	distal	-5	no	22.179	22.696	EPSD	COSMIC;CCLE	22.404	Gain
CK1_CK1_CK1-D_CSNK1E_ST	P25054	APC	P49674	CSNK1E	S906	T909P	909	Missense	distal	3	no	20.455	24.611	EPSD	COSMIC	22.404	Gain
CK1_CK1_CK1-D_CSNK1E_ST	P25054	APC	P49674	CSNK1E	S1117	N1118K	1118	Missense	proximal	1	no	22.552	22.358	EPSD	COSMIC;GDSC;CCLE	22.404	Loss
CK1_CK1_CK1-D_CSNK1E_ST	P25054	APC	P49674	CSNK1E	S1117	N1113D	1113	Missense	distal	-4	no	22.552	26.314	EPSD	COSMIC	22.404	Up-regulation
CK1_CK1_CK1-D_CSNK1E_ST	P25054	APC	P49674	CSNK1E	S1117	N1118D	1118	Missense	proximal	1	no	22.552	22.386	EPSD	COSMIC	22.404	Loss
CK1_CK1_CK1-D_CSNK1E_ST	P25054	APC	P49674	CSNK1E	S1117	T1112K	1112	Missense	distal	-5	no	22.552	22.297	EPSD	COSMIC	22.404	Loss
CK1_CK1_CK1-D_CSNK1E_ST	P25054	APC	P49674	CSNK1E	S1117	R1114G	1114	Missense	distal	-3	no	22.552	24.665	EPSD	COSMIC	22.404	Up-regulation
CK1_CK1_CK1-D_CSNK1E_ST	P25054	APC	P49674	CSNK1E	S1117	I1121S	1121	Missense	distal	4	no	22.552	22.578	EPSD	COSMIC	22.404	Up-regulation
CK1_CK1_CK1-D_CSNK1E_ST	P25054	APC	P49674	CSNK1E	S1117	S1117F	1117	Missense	central	0	yes	22.552	0.000	EPSD	COSMIC	22.404	Loss
CK1_CK1_CK1-D_CSNK1E_ST	P25054	APC	P49674	CSNK1E	S1117	G1120A	1120	Missense	distal	3	no	22.552	19.093	EPSD	COSMIC	22.404	Loss
CK1_CK1_CK1-D_CSNK1E_ST	P25054	APC	P49674	CSNK1E	S1117	T1112I	1112	Missense	distal	-5	no	22.552	22.861	EPSD	COSMIC	22.404	Up-regulation
CK1_CK1_CK1-D_CSNK1E_ST	P25054	APC	P49674	CSNK1E	S1117	H1119N	1119	Missense	proximal	2	no	22.552	22.740	EPSD	COSMIC	22.404	Up-regulation
CK1_CK1_CK1-D_CSNK1E_ST	P25054	APC	P49674	CSNK1E	S1215	E1209K	1209	Missense	distal	-6	no	20.873	23.004	EPSD	COSMIC;GDSC;CCLE	22.404	Gain
CK1_CK1_CK1-D_CSNK1E_ST	P25054	APC	P49674	CSNK1E	S1219	P1221L	1221	Missense	proximal	2	no	23.419	22.469	EPSD	COSMIC	22.404	Down-regulation
CK1_CK1_CK1-D_CSNK1E_ST	P25054	APC	P49674	CSNK1E	S1219	P1221A	1221	Missense	proximal	2	no	23.419	27.656	EPSD	COSMIC	22.404	Up-regulation
CK1_CK1_CK1-D_CSNK1E_ST	P25054	APC	P49674	CSNK1E	S1219	S1213L	1213	Missense	distal	-6	no	23.419	22.139	EPSD	COSMIC	22.404	Loss
CK1_CK1_CK1-D_CSNK1E_ST	P25054	APC	P49674	CSNK1E	S1219	S1223Y	1223	Missense	distal	4	no	23.419	23.568	EPSD	COSMIC	22.404	Up-regulation
CK1_CK1_CK1-D_CSNK1E_ST	P25054	APC	P49674	CSNK1E	S1279	E1286G	1286	Missense	distal	7	no	36.697	36.718	PhosphoSitePlus;EPSD	COSMIC	22.404	Up-regulation
CK1_CK1_CK1-D_CSNK1E_ST	P25054	APC	P49674	CSNK1E	S1279	E1284D	1284	Missense	distal	5	no	36.697	36.565	PhosphoSitePlus;EPSD	COSMIC	22.404	Down-regulation
CK1_CK1_CK1-D_CSNK1E_ST	P25054	APC	P49674	CSNK1E	S1279	S1275N	1275	Missense	distal	-4	no	36.697	31.163	PhosphoSitePlus;EPSD	COSMIC	22.404	Down-regulation
CK1_CK1_CK1-D_CSNK1E_ST	P25054	APC	P49674	CSNK1E	S1279	E1286Q	1286	Missense	distal	7	no	36.697	36.917	PhosphoSitePlus;EPSD	COSMIC	22.404	Up-regulation
CK1_CK1_CK1-D_CSNK1E_ST	P25054	APC	P49674	CSNK1E	S1279	C1274Y	1274	Missense	distal	-5	no	36.697	36.573	PhosphoSitePlus;EPSD	COSMIC	22.404	Down-regulation
CK1_CK1_CK1-D_CSNK1E_ST	P25054	APC	P49674	CSNK1E	S1279	D1285G	1285	Missense	distal	6	no	36.697	34.369	PhosphoSitePlus;EPSD	COSMIC	22.404	Down-regulation
CK1_CK1_CK1-D_CSNK1E_ST	P25054	APC	P49674	CSNK1E	S1279	R1273K	1273	Missense	distal	-6	no	36.697	37.835	PhosphoSitePlus;EPSD	COSMIC	22.404	Up-regulation
CK1_CK1_CK1-D_CSNK1E_ST	P25054	APC	P49674	CSNK1E	S1279	S1278P	1278	Missense	proximal	-1	no	36.697	35.793	PhosphoSitePlus;EPSD	COSMIC	22.404	Down-regulation
CK1_CK1_CK1-D_CSNK1E_ST	P25054	APC	P49674	CSNK1E	S1279	L1277F	1277	Missense	proximal	-2	no	36.697	35.275	PhosphoSitePlus;EPSD	COSMIC	22.404	Down-regulation
CK1_CK1_CK1-D_CSNK1E_ST	P25054	APC	P49674	CSNK1E	S1279	S1276L	1276	Missense	distal	-3	no	36.697	33.511	PhosphoSitePlus;EPSD	COSMIC	22.404	Down-regulation
CK1_CK1_CK1-D_CSNK1E_ST	P25054	APC	P49674	CSNK1E	S1279	S1276T	1276	Missense	distal	-3	no	36.697	34.803	PhosphoSitePlus;EPSD	COSMIC	22.404	Down-regulation
CK1_CK1_CK1-D_CSNK1E_ST	P25054	APC	P49674	CSNK1E	S1279	E1284K	1284	Missense	distal	5	no	36.697	36.760	PhosphoSitePlus;EPSD	COSMIC	22.404	Up-regulation
CK1_CK1_CK1-D_CSNK1E_ST	P25054	APC	P49674	CSNK1E	S1279	S1275T	1275	Missense	distal	-4	no	36.697	35.056	PhosphoSitePlus;EPSD	COSMIC;CCLE	22.404	Down-regulation
CK1_CK1_CK1-D_CSNK1E_ST	P25054	APC	P49674	CSNK1E	T1301	N1300S	1300	Missense	proximal	-1	no	16.070	22.853	EPSD	COSMIC	22.404	Gain
CK1_CK1_CK1-D_CSNK1E_ST	P25054	APC	P49674	CSNK1E	S1340	S1341R	1341	Missense	proximal	1	no	23.203	22.470	EPSD	COSMIC	22.404	Down-regulation
CK1_CK1_CK1-D_CSNK1E_ST	P25054	APC	P49674	CSNK1E	S1340	S1344F	1344	Missense	distal	4	no	23.203	23.321	EPSD	COSMIC	22.404	Up-regulation
CK1_CK1_CK1-D_CSNK1E_ST	P25054	APC	P49674	CSNK1E	S1340	G1339A	1339	Missense	proximal	-1	no	23.203	28.058	EPSD	COSMIC	22.404	Up-regulation
CK1_CK1_CK1-D_CSNK1E_ST	P25054	APC	P49674	CSNK1E	S1340	G1339D	1339	Missense	proximal	-1	no	23.203	22.694	EPSD	COSMIC	22.404	Down-regulation
CK1_CK1_CK1-D_CSNK1E_ST	P25054	APC	P49674	CSNK1E	S1340	S1346P	1346	Missense	distal	6	no	23.203	23.841	EPSD	COSMIC	22.404	Up-regulation
CK1_CK1_CK1-D_CSNK1E_ST	P25054	APC	P49674	CSNK1E	S1340	K1333R	1333	Missense	distal	-7	no	23.203	23.199	EPSD	COSMIC	22.404	Down-regulation
CK1_CK1_CK1-D_CSNK1E_ST	P25054	APC	P49674	CSNK1E	S1340	G1339S	1339	Missense	proximal	-1	no	23.203	24.383	EPSD	COSMIC	22.404	Up-regulation
CK1_CK1_CK1-D_CSNK1E_ST	P25054	APC	P49674	CSNK1E	S1340	R1336S	1336	Missense	distal	-4	no	23.203	26.688	EPSD	COSMIC	22.404	Up-regulation
CK1_CK1_CK1-D_CSNK1E_ST	P25054	APC	P49674	CSNK1E	S1340	R1336I	1336	Missense	distal	-4	no	23.203	22.349	EPSD	COSMIC	22.404	Loss
CK1_CK1_CK1-D_CSNK1E_ST	P25054	APC	P49674	CSNK1E	S1344	S1341R	1341	Missense	distal	-3	no	23.502	21.665	EPSD	COSMIC	22.404	Loss
CK1_CK1_CK1-D_CSNK1E_ST	P25054	APC	P49674	CSNK1E	S1344	S1344F	1344	Missense	central	0	yes	23.502	0.000	EPSD	COSMIC	22.404	Loss
CK1_CK1_CK1-D_CSNK1E_ST	P25054	APC	P49674	CSNK1E	S1344	G1339A	1339	Missense	distal	-5	no	23.502	23.224	EPSD	COSMIC	22.404	Down-regulation
CK1_CK1_CK1-D_CSNK1E_ST	P25054	APC	P49674	CSNK1E	S1344	G1339D	1339	Missense	distal	-5	no	23.502	22.960	EPSD	COSMIC	22.404	Down-regulation
CK1_CK1_CK1-D_CSNK1E_ST	P25054	APC	P49674	CSNK1E	S1344	H1349Y	1349	Missense	distal	5	no	23.502	24.788	EPSD	COSMIC	22.404	Up-regulation
CK1_CK1_CK1-D_CSNK1E_ST	P25054	APC	P49674	CSNK1E	S1344	R1348G	1348	Missense	distal	4	no	23.502	23.438	EPSD	COSMIC	22.404	Down-regulation
CK1_CK1_CK1-D_CSNK1E_ST	P25054	APC	P49674	CSNK1E	S1344	A1351T	1351	Missense	distal	7	no	23.502	23.610	EPSD	COSMIC	22.404	Up-regulation
CK1_CK1_CK1-D_CSNK1E_ST	P25054	APC	P49674	CSNK1E	S1344	K1350R	1350	Missense	distal	6	no	23.502	25.806	EPSD	COSMIC	22.404	Up-regulation
CK1_CK1_CK1-D_CSNK1E_ST	P25054	APC	P49674	CSNK1E	S1344	S1346P	1346	Missense	proximal	2	no	23.502	21.927	EPSD	COSMIC	22.404	Loss
CK1_CK1_CK1-D_CSNK1E_ST	P25054	APC	P49674	CSNK1E	S1344	K1350T	1350	Missense	distal	6	no	23.502	21.045	EPSD	COSMIC	22.404	Loss
CK1_CK1_CK1-D_CSNK1E_ST	P25054	APC	P49674	CSNK1E	S1344	G1339S	1339	Missense	distal	-5	no	23.502	23.869	EPSD	COSMIC	22.404	Up-regulation
CK1_CK1_CK1-D_CSNK1E_ST	P25054	APC	P49674	CSNK1E	S1364	K1363E	1363	Missense	proximal	-1	no	19.895	23.402	EPSD	COSMIC	22.404	Gain
CK1_CK1_CK1-D_CSNK1E_ST	P25054	APC	P49674	CSNK1E	T1368	A1366G	1366	Missense	proximal	-2	no	27.840	24.780	EPSD	COSMIC	22.404	Down-regulation
CK1_CK1_CK1-D_CSNK1E_ST	P25054	APC	P49674	CSNK1E	T1368	P1361L	1361	Missense	distal	-7	no	27.840	27.835	EPSD	COSMIC	22.404	Down-regulation
CK1_CK1_CK1-D_CSNK1E_ST	P25054	APC	P49674	CSNK1E	T1368	S1362F	1362	Missense	distal	-6	no	27.840	26.690	EPSD	COSMIC	22.404	Down-regulation
CK1_CK1_CK1-D_CSNK1E_ST	P25054	APC	P49674	CSNK1E	T1368	P1373S	1373	Missense	distal	5	no	27.840	27.547	EPSD	COSMIC	22.404	Down-regulation
CK1_CK1_CK1-D_CSNK1E_ST	P25054	APC	P49674	CSNK1E	T1368	T1368I	1368	Missense	central	0	yes	27.840	0.000	EPSD	COSMIC	22.404	Loss
CK1_CK1_CK1-D_CSNK1E_ST	P25054	APC	P49674	CSNK1E	T1368	S1364R	1364	Missense	distal	-4	no	27.840	24.355	EPSD	COSMIC	22.404	Down-regulation
CK1_CK1_CK1-D_CSNK1E_ST	P25054	APC	P49674	CSNK1E	T1368	P1369H	1369	Missense	proximal	1	no	27.840	27.833	EPSD	COSMIC	22.404	Down-regulation
CK1_CK1_CK1-D_CSNK1E_ST	P25054	APC	P49674	CSNK1E	T1368	K1363I	1363	Missense	distal	-5	no	27.840	28.404	EPSD	COSMIC	22.404	Up-regulation
CK1_CK1_CK1-D_CSNK1E_ST	P25054	APC	P49674	CSNK1E	T1368	K1363E	1363	Missense	distal	-5	no	27.840	28.722	EPSD	COSMIC	22.404	Up-regulation
CK1_CK1_CK1-D_CSNK1E_ST	P25054	APC	P49674	CSNK1E	T1368	E1374K	1374	Missense	distal	6	no	27.840	29.530	EPSD	COSMIC	22.404	Up-regulation
CK1_CK1_CK1-D_CSNK1E_ST	P25054	APC	P49674	CSNK1E	T1368	Q1367R	1367	Missense	proximal	-1	no	27.840	24.993	EPSD	COSMIC	22.404	Down-regulation
CK1_CK1_CK1-D_CSNK1E_ST	P25054	APC	P49674	CSNK1E	T1368	H1375Y	1375	Missense	distal	7	no	27.840	28.291	EPSD	COSMIC	22.404	Up-regulation
CK1_CK1_CK1-D_CSNK1E_ST	P25054	APC	P49674	CSNK1E	T1368	Q1367H	1367	Missense	proximal	-1	no	27.840	25.548	EPSD	COSMIC	22.404	Down-regulation
CK1_CK1_CK1-D_CSNK1E_ST	P25054	APC	P49674	CSNK1E	T1368	P1373T	1373	Missense	distal	5	no	27.840	27.501	EPSD	COSMIC	22.404	Down-regulation
CK1_CK1_CK1-D_CSNK1E_ST	P25054	APC	P49674	CSNK1E	T1368	P1373L	1373	Missense	distal	5	no	27.840	28.832	EPSD	COSMIC	22.404	Up-regulation
CK1_CK1_CK1-D_CSNK1E_ST	P25054	APC	P49674	CSNK1E	T1368	G1365D	1365	Missense	distal	-3	no	27.840	27.736	EPSD	COSMIC	22.404	Down-regulation
CK1_CK1_CK1-D_CSNK1E_ST	P25054	APC	P49674	CSNK1E	T1368	T1368K	1368	Missense	central	0	yes	27.840	0.000	EPSD	COSMIC	22.404	Loss
CK1_CK1_CK1-D_CSNK1E_ST	P25054	APC	P49674	CSNK1E	S1389	V1390I	1390	Missense	proximal	1	no	25.057	25.345	EPSD	COSMIC	22.404	Up-regulation
CK1_CK1_CK1-D_CSNK1E_ST	P25054	APC	P49674	CSNK1E	S1389	R1386S	1386	Missense	distal	-3	no	25.057	26.895	EPSD	COSMIC	22.404	Up-regulation
CK1_CK1_CK1-D_CSNK1E_ST	P25054	APC	P49674	CSNK1E	S1389	S1389C	1389	Missense	central	0	yes	25.057	0.000	EPSD	COSMIC	22.404	Loss
CK1_CK1_CK1-D_CSNK1E_ST	P25054	APC	P49674	CSNK1E	S1389	S1385R	1385	Missense	distal	-4	no	25.057	21.573	EPSD	COSMIC	22.404	Loss
CK1_CK1_CK1-D_CSNK1E_ST	P25054	APC	P49674	CSNK1E	S1389	C1387S	1387	Missense	proximal	-2	no	25.057	32.231	EPSD	COSMIC	22.404	Up-regulation
CK1_CK1_CK1-D_CSNK1E_ST	P25054	APC	P49674	CSNK1E	S1389	L1382F	1382	Missense	distal	-7	no	25.057	25.059	EPSD	COSMIC	22.404	Up-regulation
CK1_CK1_CK1-D_CSNK1E_ST	P25054	APC	P49674	CSNK1E	S1389	D1394N	1394	Missense	distal	5	no	25.057	25.402	EPSD	COSMIC	22.404	Up-regulation
CK1_CK1_CK1-D_CSNK1E_ST	P25054	APC	P49674	CSNK1E	S1389	S1395C	1395	Missense	distal	6	no	25.057	19.895	EPSD	COSMIC	22.404	Loss
CK1_CK1_CK1-D_CSNK1E_ST	P25054	APC	P49674	CSNK1E	S1389	L1382P	1382	Missense	distal	-7	no	25.057	25.062	EPSD	COSMIC	22.404	Up-regulation
CK1_CK1_CK1-D_CSNK1E_ST	P25054	APC	P49674	CSNK1E	S1389	V1390D	1390	Missense	proximal	1	no	25.057	24.879	EPSD	COSMIC	22.404	Down-regulation
CK1_CK1_CK1-D_CSNK1E_ST	P25054	APC	P49674	CSNK1E	S1389	S1389Y	1389	Missense	central	0	yes	25.057	0.000	EPSD	COSMIC	22.404	Loss
CK1_CK1_CK1-D_CSNK1E_ST	P25054	APC	P49674	CSNK1E	S1389	L1393P	1393	Missense	distal	4	no	25.057	24.947	EPSD	COSMIC	22.404	Down-regulation
CK1_CK1_CK1-D_CSNK1E_ST	P25054	APC	P49674	CSNK1E	S1391	C1387S	1387	Missense	distal	-4	no	16.567	23.166	EPSD	COSMIC	22.404	Gain
CK1_CK1_CK1-D_CSNK1E_ST	P25054	APC	P49674	CSNK1E	S1392	V1390I	1390	Missense	proximal	-2	no	34.913	35.252	EPSD;PhosphoSitePlus	COSMIC	22.404	Up-regulation
CK1_CK1_CK1-D_CSNK1E_ST	P25054	APC	P49674	CSNK1E	S1392	R1386S	1386	Missense	distal	-6	no	34.913	36.238	EPSD;PhosphoSitePlus	COSMIC	22.404	Up-regulation
CK1_CK1_CK1-D_CSNK1E_ST	P25054	APC	P49674	CSNK1E	S1392	S1389C	1389	Missense	distal	-3	no	34.913	31.639	EPSD;PhosphoSitePlus	COSMIC	22.404	Down-regulation
CK1_CK1_CK1-D_CSNK1E_ST	P25054	APC	P49674	CSNK1E	S1392	S1385R	1385	Missense	distal	-7	no	34.913	34.907	EPSD;PhosphoSitePlus	COSMIC	22.404	Down-regulation
CK1_CK1_CK1-D_CSNK1E_ST	P25054	APC	P49674	CSNK1E	S1392	C1387S	1387	Missense	distal	-5	no	34.913	36.474	EPSD;PhosphoSitePlus	COSMIC	22.404	Up-regulation
CK1_CK1_CK1-D_CSNK1E_ST	P25054	APC	P49674	CSNK1E	S1392	S1398T	1398	Missense	distal	6	no	34.913	30.328	EPSD;PhosphoSitePlus	COSMIC	22.404	Down-regulation
CK1_CK1_CK1-D_CSNK1E_ST	P25054	APC	P49674	CSNK1E	S1392	D1394N	1394	Missense	proximal	2	no	34.913	35.541	EPSD;PhosphoSitePlus	COSMIC	22.404	Up-regulation
CK1_CK1_CK1-D_CSNK1E_ST	P25054	APC	P49674	CSNK1E	S1392	S1395C	1395	Missense	distal	3	no	34.913	25.821	EPSD;PhosphoSitePlus	COSMIC	22.404	Down-regulation
CK1_CK1_CK1-D_CSNK1E_ST	P25054	APC	P49674	CSNK1E	S1392	V1390D	1390	Missense	proximal	-2	no	34.913	32.008	EPSD;PhosphoSitePlus	COSMIC	22.404	Down-regulation
CK1_CK1_CK1-D_CSNK1E_ST	P25054	APC	P49674	CSNK1E	S1392	S1389Y	1389	Missense	distal	-3	no	34.913	30.683	EPSD;PhosphoSitePlus	COSMIC	22.404	Down-regulation
CK1_CK1_CK1-D_CSNK1E_ST	P25054	APC	P49674	CSNK1E	S1392	L1393P	1393	Missense	proximal	1	no	34.913	35.269	EPSD;PhosphoSitePlus	COSMIC	22.404	Up-regulation
CK1_CK1_CK1-D_CSNK1E_ST	P25054	APC	P49674	CSNK1E	S1392	S1398N	1398	Missense	distal	6	no	34.913	31.721	EPSD;PhosphoSitePlus	COSMIC	22.404	Down-regulation
CK1_CK1_CK1-D_CSNK1E_ST	P25054	APC	P49674	CSNK1E	T1459	K1462R	1462	Missense	distal	3	no	20.494	23.966	EPSD	COSMIC	22.404	Gain
CK1_CK1_CK1-D_CSNK1E_ST	P25054	APC	P49674	CSNK1E	T1459	N1455D	1455	Missense	distal	-4	no	20.494	24.256	EPSD	COSMIC	22.404	Gain
CK1_CK1_CK1-D_CSNK1E_ST	P25054	APC	P49674	CSNK1E	S1505	S1501A	1501	Missense	distal	-4	no	29.860	30.752	EPSD	COSMIC	22.404	Up-regulation
CK1_CK1_CK1-D_CSNK1E_ST	P25054	APC	P49674	CSNK1E	S1505	G1499R	1499	Missense	distal	-6	no	29.860	29.621	EPSD	COSMIC	22.404	Down-regulation
CK1_CK1_CK1-D_CSNK1E_ST	P25054	APC	P49674	CSNK1E	S1505	D1512N	1512	Missense	distal	7	no	29.860	30.254	EPSD	COSMIC	22.404	Up-regulation
CK1_CK1_CK1-D_CSNK1E_ST	P25054	APC	P49674	CSNK1E	S1505	D1498N	1498	Missense	distal	-7	no	29.860	29.858	EPSD	COSMIC	22.404	Down-regulation
CK1_CK1_CK1-D_CSNK1E_ST	P25054	APC	P49674	CSNK1E	S1505	S1504F	1504	Missense	proximal	-1	no	29.860	22.153	EPSD	COSMIC	22.404	Loss
CK1_CK1_CK1-D_CSNK1E_ST	P25054	APC	P49674	CSNK1E	S1505	A1508V	1508	Missense	distal	3	no	29.860	27.434	EPSD	COSMIC	22.404	Down-regulation
CK1_CK1_CK1-D_CSNK1E_ST	P25054	APC	P49674	CSNK1E	S1505	S1503L	1503	Missense	proximal	-2	no	29.860	23.245	EPSD	COSMIC	22.404	Down-regulation
CK1_CK1_CK1-D_CSNK1E_ST	P25054	APC	P49674	CSNK1E	S1505	S1501F	1501	Missense	distal	-4	no	29.860	24.737	EPSD	COSMIC	22.404	Down-regulation
CK1_CK1_CK1-D_CSNK1E_ST	P25054	APC	P49674	CSNK1E	S1505	D1512V	1512	Missense	distal	7	no	29.860	30.598	EPSD	COSMIC	22.404	Up-regulation
CK1_CK1_CK1-D_CSNK1E_ST	P25054	APC	P49674	CSNK1E	S1539	T1537K	1537	Missense	proximal	-2	no	23.087	21.885	EPSD	COSMIC	22.404	Loss
CK1_CK1_CK1-D_CSNK1E_ST	P25054	APC	P49674	CSNK1E	S1539	E1536K	1536	Missense	distal	-3	no	23.087	24.177	EPSD	COSMIC	22.404	Up-regulation
CK1_CK1_CK1-D_CSNK1E_ST	P25054	APC	P49674	CSNK1E	S1539	S1545L	1545	Missense	distal	6	no	23.087	19.930	EPSD	COSMIC;GDSC;CCLE	22.404	Loss
CK1_CK1_CK1-D_CSNK1E_ST	P25054	APC	P49674	CSNK1E	S1539	G1534V	1534	Missense	distal	-5	no	23.087	22.853	EPSD	COSMIC	22.404	Down-regulation
CK1_CK1_CK1-D_CSNK1E_ST	P25054	APC	P49674	CSNK1E	S1539	G1534R	1534	Missense	distal	-5	no	23.087	22.076	EPSD	COSMIC	22.404	Loss
CK1_CK1_CK1-D_CSNK1E_ST	P25054	APC	P49674	CSNK1E	S1539	G1534E	1534	Missense	distal	-5	no	23.087	22.773	EPSD	COSMIC	22.404	Down-regulation
CK1_CK1_CK1-D_CSNK1E_ST	P25054	APC	P49674	CSNK1E	S1539	N1533D	1533	Missense	distal	-6	no	23.087	22.618	EPSD	COSMIC	22.404	Down-regulation
CK1_CK1_CK1-D_CSNK1E_ST	P25054	APC	P49674	CSNK1E	S1539	E1544K	1544	Missense	distal	5	no	23.087	23.150	EPSD	COSMIC	22.404	Up-regulation
CK1_CK1_CK1-D_CSNK1E_ST	P25054	APC	P49674	CSNK1E	S1610	R1607K	1607	Missense	distal	-3	no	23.379	23.933	EPSD	COSMIC	22.404	Up-regulation
CK1_CK1_CK1-D_CSNK1E_ST	P25054	APC	P49674	CSNK1E	S1610	P1609S	1609	Missense	proximal	-1	no	23.379	24.283	EPSD	COSMIC	22.404	Up-regulation
CK1_CK1_CK1-D_CSNK1E_ST	P25054	APC	P49674	CSNK1E	S1610	P1609L	1609	Missense	proximal	-1	no	23.379	15.976	EPSD	COSMIC	22.404	Loss
CK1_CK1_CK1-D_CSNK1E_ST	P25054	APC	P49674	CSNK1E	S1610	P1604S	1604	Missense	distal	-6	no	23.379	24.036	EPSD	COSMIC	22.404	Up-regulation
CK1_CK1_CK1-D_CSNK1E_ST	P25054	APC	P49674	CSNK1E	S1610	R1607S	1607	Missense	distal	-3	no	23.379	25.217	EPSD	COSMIC	22.404	Up-regulation
CK1_CK1_CK1-D_CSNK1E_ST	P25054	APC	P49674	CSNK1E	S1656	S1652P	1652	Missense	distal	-4	no	34.573	32.758	EPSD	COSMIC	22.404	Down-regulation
CK1_CK1_CK1-D_CSNK1E_ST	P25054	APC	P49674	CSNK1E	S1656	S1656F	1656	Missense	central	0	yes	34.573	0.000	EPSD	COSMIC	22.404	Loss
CK1_CK1_CK1-D_CSNK1E_ST	P25054	APC	P49674	CSNK1E	S1656	L1660P	1660	Missense	distal	4	no	34.573	34.463	EPSD	COSMIC	22.404	Down-regulation
CK1_CK1_CK1-D_CSNK1E_ST	P25054	APC	P49674	CSNK1E	S1656	E1663K	1663	Missense	distal	7	no	34.573	34.928	EPSD	COSMIC	22.404	Up-regulation
CK1_CK1_CK1-D_CSNK1E_ST	P25054	APC	P49674	CSNK1E	S1656	S1656Y	1656	Missense	central	0	yes	34.573	0.000	EPSD	COSMIC;GDSC;CCLE	22.404	Loss
CK1_CK1_CK1-D_CSNK1E_ST	P25054	APC	P49674	CSNK1E	S1656	L1657R	1657	Missense	proximal	1	no	34.573	34.492	EPSD	COSMIC	22.404	Down-regulation
CK1_CK1_CK1-D_CSNK1E_ST	P25054	APC	P49674	CSNK1E	S1656	S1658R	1658	Missense	proximal	2	no	34.573	31.789	EPSD	COSMIC	22.404	Down-regulation
CK1_CK1_CK1-D_CSNK1E_ST	P25054	APC	P49674	CSNK1E	S1664	L1660P	1660	Missense	distal	-4	no	21.160	27.638	EPSD	COSMIC	22.404	Gain
CK1_CK1_CK1-D_CSNK1E_ST	P25054	APC	P49674	CSNK1E	S1754	A1759E	1759	Missense	distal	5	no	25.033	25.140	EPSD	COSMIC	22.404	Up-regulation
CK1_CK1_CK1-D_CSNK1E_ST	P25054	APC	P49674	CSNK1E	S1754	P1760R	1760	Missense	distal	6	no	25.033	24.571	EPSD	COSMIC	22.404	Down-regulation
CK1_CK1_CK1-D_CSNK1E_ST	P25054	APC	P49674	CSNK1E	S1754	D1748N	1748	Missense	distal	-6	no	25.033	25.502	EPSD	COSMIC	22.404	Up-regulation
CK1_CK1_CK1-D_CSNK1E_ST	P25054	APC	P49674	CSNK1E	S1754	S1756C	1756	Missense	proximal	2	no	25.033	23.231	EPSD	COSMIC	22.404	Down-regulation
CK1_CK1_CK1-D_CSNK1E_ST	P25054	APC	P49674	CSNK1E	S1757	A1759E	1759	Missense	proximal	2	no	26.313	23.792	EPSD	COSMIC	22.404	Down-regulation
CK1_CK1_CK1-D_CSNK1E_ST	P25054	APC	P49674	CSNK1E	S1757	P1760R	1760	Missense	distal	3	no	26.313	25.251	EPSD	COSMIC	22.404	Down-regulation
CK1_CK1_CK1-D_CSNK1E_ST	P25054	APC	P49674	CSNK1E	S1757	S1756C	1756	Missense	proximal	-1	no	26.313	19.040	EPSD	COSMIC	22.404	Loss
CK1_CK1_CK1-D_CSNK1E_ST	P25054	APC	P49674	CSNK1E	S1896	N1903S	1903	Missense	distal	7	no	24.125	23.571	EPSD	COSMIC	22.404	Down-regulation
CK1_CK1_CK1-D_CSNK1E_ST	P25054	APC	P49674	CSNK1E	S1896	S1890L	1890	Missense	distal	-6	no	24.125	22.845	EPSD	COSMIC;GDSC;CCLE	22.404	Down-regulation
CK1_CK1_CK1-D_CSNK1E_ST	P25054	APC	P49674	CSNK1E	S1896	E1891K	1891	Missense	distal	-5	no	24.125	23.243	EPSD	COSMIC	22.404	Down-regulation
CK1_CK1_CK1-D_CSNK1E_ST	P25054	APC	P49674	CSNK1E	S1896	H1897P	1897	Missense	proximal	1	no	24.125	24.132	EPSD	COSMIC	22.404	Up-regulation
CK1_CK1_CK1-D_CSNK1E_ST	P25054	APC	P49674	CSNK1E	S1896	N1903Y	1903	Missense	distal	7	no	24.125	24.457	EPSD	COSMIC	22.404	Up-regulation
CK1_CK1_CK1-D_CSNK1E_ST	P25054	APC	P49674	CSNK1E	S1896	E1889G	1889	Missense	distal	-7	no	24.125	24.126	EPSD	COSMIC	22.404	Up-regulation
CK1_CK1_CK1-D_CSNK1E_ST	P25054	APC	P49674	CSNK1E	T1898	H1897P	1897	Missense	proximal	-1	no	17.832	22.636	EPSD	COSMIC	22.404	Gain
CK1_CK1_CK1-D_CSNK1E_ST	P25054	APC	P49674	CSNK1E	S2110	V2112I	2112	Missense	proximal	2	no	29.100	29.143	EPSD	COSMIC	22.404	Up-regulation
CK1_CK1_CK1-D_CSNK1E_ST	P25054	APC	P49674	CSNK1E	S2110	S2110F	2110	Missense	central	0	yes	29.100	0.000	EPSD	COSMIC	22.404	Loss
CK1_CK1_CK1-D_CSNK1E_ST	P25054	APC	P49674	CSNK1E	S2110	A2108T	2108	Missense	proximal	-2	no	29.100	25.453	EPSD	COSMIC	22.404	Down-regulation
CK1_CK1_CK1-D_CSNK1E_ST	P25054	APC	P49674	CSNK1E	S2110	S2113R	2113	Missense	distal	3	no	29.100	27.055	EPSD	COSMIC	22.404	Down-regulation
CK1_CK1_CK1-D_CSNK1E_ST	P25054	APC	P49674	CSNK1E	S2134	L2136F	2136	Missense	proximal	2	no	21.817	23.154	EPSD	COSMIC	22.404	Gain
CK1_CK1_CK1-D_CSNK1E_ST	P25054	APC	P49674	CSNK1E	S2140	L2136F	2136	Missense	distal	-4	no	19.515	22.685	EPSD	COSMIC	22.404	Gain
CK1_CK1_CK1-D_CSNK1E_ST	P25054	APC	P49674	CSNK1E	S2185	G2187E	2187	Missense	proximal	2	no	21.201	22.633	EPSD	COSMIC	22.404	Gain
CK1_CK1_CK1-D_CSNK1E_ST	P25054	APC	P49674	CSNK1E	S2241	S2241L	2241	Missense	central	0	yes	30.815	0.000	EPSD	COSMIC	22.404	Loss
CK1_CK1_CK1-D_CSNK1E_ST	P25054	APC	P49674	CSNK1E	S2241	V2236A	2236	Missense	distal	-5	no	30.815	30.771	EPSD	COSMIC	22.404	Down-regulation
CK1_CK1_CK1-D_CSNK1E_ST	P25054	APC	P49674	CSNK1E	S2241	V2246I	2246	Missense	distal	5	no	30.815	30.389	EPSD	COSMIC	22.404	Down-regulation
CK1_CK1_CK1-D_CSNK1E_ST	P25054	APC	P49674	CSNK1E	S2241	P2234L	2234	Missense	distal	-7	no	30.815	30.811	EPSD	COSMIC	22.404	Down-regulation
CK1_CK1_CK1-D_CSNK1E_ST	P25054	APC	P49674	CSNK1E	S2241	S2247P	2247	Missense	distal	6	no	30.815	31.453	EPSD	COSMIC	22.404	Up-regulation
CK1_CK1_CK1-D_CSNK1E_ST	P25054	APC	P49674	CSNK1E	S2241	R2237L	2237	Missense	distal	-4	no	30.815	26.007	EPSD	COSMIC	22.404	Down-regulation
CK1_CK1_CK1-D_CSNK1E_ST	P25054	APC	P49674	CSNK1E	S2241	S2242G	2242	Missense	proximal	1	no	30.815	29.836	EPSD	COSMIC	22.404	Down-regulation
CK1_CK1_CK1-D_CSNK1E_ST	P25054	APC	P49674	CSNK1E	S2244	S2241L	2241	Missense	distal	-3	no	27.434	24.248	EPSD	COSMIC	22.404	Down-regulation
CK1_CK1_CK1-D_CSNK1E_ST	P25054	APC	P49674	CSNK1E	S2244	V2246I	2246	Missense	proximal	2	no	27.434	27.477	EPSD	COSMIC	22.404	Up-regulation
CK1_CK1_CK1-D_CSNK1E_ST	P25054	APC	P49674	CSNK1E	S2244	S2247P	2247	Missense	distal	3	no	27.434	26.452	EPSD	COSMIC	22.404	Down-regulation
CK1_CK1_CK1-D_CSNK1E_ST	P25054	APC	P49674	CSNK1E	S2244	R2237L	2237	Missense	distal	-7	no	27.434	27.435	EPSD	COSMIC	22.404	Up-regulation
CK1_CK1_CK1-D_CSNK1E_ST	P25054	APC	P49674	CSNK1E	S2244	S2242G	2242	Missense	proximal	-2	no	27.434	25.233	EPSD	COSMIC	22.404	Down-regulation
CK1_CK1_CK1-D_CSNK1E_ST	P25054	APC	P49674	CSNK1E	S2244	K2249Q	2249	Missense	distal	5	no	27.434	26.560	EPSD	COSMIC	22.404	Down-regulation
CK1_CK1_CK1-D_CSNK1E_ST	P25054	APC	P49674	CSNK1E	S2247	V2246I	2246	Missense	proximal	-1	no	20.654	23.412	EPSD	COSMIC	22.404	Gain
CK1_CK1_CK1-D_CSNK1E_ST	P25054	APC	P49674	CSNK1E	T2266	T2266I	2266	Missense	central	0	yes	23.530	0.000	EPSD	COSMIC	22.404	Loss
CK1_CK1_CK1-D_CSNK1E_ST	P25054	APC	P49674	CSNK1E	T2266	T2268S	2268	Missense	proximal	2	no	23.530	22.696	EPSD	COSMIC	22.404	Down-regulation
CK1_CK1_CK1-D_CSNK1E_ST	P25054	APC	P49674	CSNK1E	T2266	S2270C	2270	Missense	distal	4	no	23.530	23.708	EPSD	COSMIC	22.404	Up-regulation
CK1_CK1_CK1-D_CSNK1E_ST	P25054	APC	P49674	CSNK1E	T2268	T2266I	2266	Missense	proximal	-2	no	20.565	22.565	EPSD	COSMIC	22.404	Gain
CK1_CK1_CK1-D_CSNK1E_ST	P25054	APC	P49674	CSNK1E	T2268	T2266S	2266	Missense	proximal	-2	no	20.565	23.354	EPSD	COSMIC	22.404	Gain
CK1_CK1_CK1-D_CSNK1E_ST	P25054	APC	P49674	CSNK1E	S2270	T2266I	2266	Missense	distal	-4	no	22.607	19.910	EPSD	COSMIC	22.404	Loss
CK1_CK1_CK1-D_CSNK1E_ST	P25054	APC	P49674	CSNK1E	S2270	T2266S	2266	Missense	distal	-4	no	22.607	24.248	EPSD	COSMIC	22.404	Up-regulation
CK1_CK1_CK1-D_CSNK1E_ST	P25054	APC	P49674	CSNK1E	S2270	T2268S	2268	Missense	proximal	-2	no	22.607	25.396	EPSD	COSMIC	22.404	Up-regulation
CK1_CK1_CK1-D_CSNK1E_ST	P25054	APC	P49674	CSNK1E	S2270	S2277F	2277	Missense	distal	7	no	22.607	23.340	EPSD	COSMIC	22.404	Up-regulation
CK1_CK1_CK1-D_CSNK1E_ST	P25054	APC	P49674	CSNK1E	S2270	A2274V	2274	Missense	distal	4	no	22.607	22.671	EPSD	COSMIC;GDSC	22.404	Up-regulation
CK1_CK1_CK1-D_CSNK1E_ST	P25054	APC	P49674	CSNK1E	S2270	S2270C	2270	Missense	central	0	yes	22.607	0.000	EPSD	COSMIC	22.404	Loss
CK1_CK1_CK1-D_CSNK1E_ST	P25054	APC	P49674	CSNK1E	S2302	S2307T	2307	Missense	distal	5	no	23.817	23.771	EPSD	COSMIC	22.404	Down-regulation
CK1_CK1_CK1-D_CSNK1E_ST	P25054	APC	P49674	CSNK1E	S2302	S2296N	2296	Missense	distal	-6	no	23.817	23.384	EPSD	COSMIC	22.404	Down-regulation
CK1_CK1_CK1-D_CSNK1E_ST	P25054	APC	P49674	CSNK1E	S2302	G2303R	2303	Missense	proximal	1	no	23.817	24.063	EPSD	COSMIC	22.404	Up-regulation
CK1_CK1_CK1-D_CSNK1E_ST	P25054	APC	P49674	CSNK1E	S2302	S2302L	2302	Missense	central	0	yes	23.817	0.000	EPSD	COSMIC	22.404	Loss
CK1_CK1_CK1-D_CSNK1E_ST	P25054	APC	P49674	CSNK1E	S2302	K2297E	2297	Missense	distal	-5	no	23.817	24.699	EPSD	COSMIC	22.404	Up-regulation
CK1_CK1_CK1-D_CSNK1E_ST	P25054	APC	P49674	CSNK1E	S2302	S2295L	2295	Missense	distal	-7	no	23.817	23.811	EPSD	COSMIC	22.404	Down-regulation
CK1_CK1_CK1-D_CSNK1E_ST	P25054	APC	P49674	CSNK1E	S2302	P2309L	2309	Missense	distal	7	no	23.817	24.202	EPSD	COSMIC	22.404	Up-regulation
CK1_CK1_CK1-D_CSNK1E_ST	P25054	APC	P49674	CSNK1E	S2304	S2307T	2307	Missense	distal	3	no	23.361	18.222	EPSD	COSMIC	22.404	Loss
CK1_CK1_CK1-D_CSNK1E_ST	P25054	APC	P49674	CSNK1E	S2304	G2303R	2303	Missense	proximal	-1	no	23.361	18.278	EPSD	COSMIC	22.404	Loss
CK1_CK1_CK1-D_CSNK1E_ST	P25054	APC	P49674	CSNK1E	S2304	S2302L	2302	Missense	proximal	-2	no	23.361	16.746	EPSD	COSMIC	22.404	Loss
CK1_CK1_CK1-D_CSNK1E_ST	P25054	APC	P49674	CSNK1E	S2304	K2297E	2297	Missense	distal	-7	no	23.361	23.360	EPSD	COSMIC	22.404	Down-regulation
CK1_CK1_CK1-D_CSNK1E_ST	P25054	APC	P49674	CSNK1E	S2304	P2309L	2309	Missense	distal	5	no	23.361	24.353	EPSD	COSMIC	22.404	Up-regulation
CK1_CK1_CK1-D_CSNK1E_ST	P25054	APC	P49674	CSNK1E	S2304	R2311T	2311	Missense	distal	7	no	23.361	23.610	EPSD	COSMIC	22.404	Up-regulation
CK1_CK1_CK1-D_CSNK1E_ST	P25054	APC	P49674	CSNK1E	S2349	T2348A	2348	Missense	proximal	-1	no	17.648	23.423	EPSD	COSMIC	22.404	Gain
CK1_CK1_CK1-D_CSNK1E_ST	P25054	APC	P49674	CSNK1E	S2359	S2355L	2355	Missense	distal	-4	no	22.635	14.343	EPSD	COSMIC	22.404	Loss
CK1_CK1_CK1-D_CSNK1E_ST	P25054	APC	P49674	CSNK1E	S2359	T2356I	2356	Missense	distal	-3	no	22.635	24.010	EPSD	COSMIC	22.404	Up-regulation
CK1_CK1_CK1-D_CSNK1E_ST	P25054	APC	P49674	CSNK1E	S2390	K2386M	2386	Missense	distal	-4	no	23.664	27.215	EPSD	COSMIC	22.404	Up-regulation
CK1_CK1_CK1-D_CSNK1E_ST	P25054	APC	P49674	CSNK1E	S2390	K2386N	2386	Missense	distal	-4	no	23.664	23.881	EPSD	COSMIC	22.404	Up-regulation
CK1_CK1_CK1-D_CSNK1E_ST	P25054	APC	P49674	CSNK1E	S2390	L2384I	2384	Missense	distal	-6	no	23.664	25.119	EPSD	COSMIC;CCLE	22.404	Up-regulation
CK1_CK1_CK1-D_CSNK1E_ST	P25054	APC	P49674	CSNK1E	S2390	P2392S	2392	Missense	proximal	2	no	23.664	25.239	EPSD	COSMIC	22.404	Up-regulation
CK1_CK1_CK1-D_CSNK1E_ST	P25054	APC	P49674	CSNK1E	S2396	N2402K	2402	Missense	distal	6	no	22.425	23.489	EPSD	COSMIC	22.404	Up-regulation
CK1_CK1_CK1-D_CSNK1E_ST	P25054	APC	P49674	CSNK1E	S2396	P2392S	2392	Missense	distal	-4	no	22.425	24.240	EPSD	COSMIC	22.404	Up-regulation
CK1_CK1_CK1-D_CSNK1E_ST	P25054	APC	P49674	CSNK1E	T2422	S2421T	2421	Missense	proximal	-1	no	23.894	21.794	EPSD	COSMIC	22.404	Loss
CK1_CK1_CK1-D_CSNK1E_ST	P25054	APC	P49674	CSNK1E	T2422	S2417Y	2417	Missense	distal	-5	no	23.894	22.210	EPSD	COSMIC	22.404	Loss
CK1_CK1_CK1-D_CSNK1E_ST	P25054	APC	P49674	CSNK1E	T2422	E2428K	2428	Missense	distal	6	no	23.894	25.584	EPSD	COSMIC	22.404	Up-regulation
CK1_CK1_CK1-D_CSNK1E_ST	P25054	APC	P49674	CSNK1E	T2422	E2415Q	2415	Missense	distal	-7	no	23.894	23.895	EPSD	COSMIC	22.404	Up-regulation
CK1_CK1_CK1-D_CSNK1E_ST	P25054	APC	P49674	CSNK1E	S2425	S2421T	2421	Missense	distal	-4	no	32.289	30.647	EPSD	COSMIC	22.404	Down-regulation
CK1_CK1_CK1-D_CSNK1E_ST	P25054	APC	P49674	CSNK1E	S2425	D2430N	2430	Missense	distal	5	no	32.289	32.633	EPSD	COSMIC	22.404	Up-regulation
CK1_CK1_CK1-D_CSNK1E_ST	P25054	APC	P49674	CSNK1E	S2425	E2428K	2428	Missense	distal	3	no	32.289	32.191	EPSD	COSMIC	22.404	Down-regulation
CK1_CK1_CK1-D_CSNK1E_ST	P25054	APC	P49674	CSNK1E	S2425	T2422S	2422	Missense	distal	-3	no	32.289	34.183	EPSD	COSMIC	22.404	Up-regulation
CK1_CK1_CK1-D_CSNK1E_ST	P25054	APC	P49674	CSNK1E	S2464	S2466F	2466	Missense	proximal	2	no	27.851	26.664	EPSD	COSMIC	22.404	Down-regulation
CK1_CK1_CK1-D_CSNK1E_ST	P25054	APC	P49674	CSNK1E	S2464	P2467S	2467	Missense	distal	3	no	27.851	28.833	EPSD	COSMIC;GDSC;CCLE	22.404	Up-regulation
CK1_CK1_CK1-D_CSNK1E_ST	P25054	APC	P49674	CSNK1E	S2464	P2467T	2467	Missense	distal	3	no	27.851	23.695	EPSD	COSMIC	22.404	Down-regulation
CK1_CK1_CK1-D_CSNK1E_ST	P25054	APC	P49674	CSNK1E	S2464	R2470G	2470	Missense	distal	6	no	27.851	25.160	EPSD	COSMIC	22.404	Down-regulation
CK1_CK1_CK1-D_CSNK1E_ST	P25054	APC	P49674	CSNK1E	S2464	R2470T	2470	Missense	distal	6	no	27.851	23.091	EPSD	COSMIC	22.404	Down-regulation
CK1_CK1_CK1-D_CSNK1E_ST	P25054	APC	P49674	CSNK1E	S2464	E2457G	2457	Missense	distal	-7	no	27.851	27.852	EPSD	COSMIC	22.404	Up-regulation
CK1_CK1_CK1-D_CSNK1E_ST	P25054	APC	P49674	CSNK1E	S2464	E2457D	2457	Missense	distal	-7	no	27.851	27.852	EPSD	COSMIC	22.404	Up-regulation
CK1_CK1_CK1-D_CSNK1E_ST	P25054	APC	P49674	CSNK1E	S2464	E2458V	2458	Missense	distal	-6	no	27.851	28.772	EPSD	COSMIC	22.404	Up-regulation
CK1_CK1_CK1-D_CSNK1E_ST	P25054	APC	P49674	CSNK1E	S2464	R2470K	2470	Missense	distal	6	no	27.851	25.548	EPSD	COSMIC	22.404	Down-regulation
CK1_CK1_CK1-D_CSNK1E_ST	P25054	APC	P49674	CSNK1E	S2464	S2466Y	2466	Missense	proximal	2	no	27.851	27.683	EPSD	COSMIC	22.404	Down-regulation
CK1_CK1_CK1-D_CSNK1E_ST	P25054	APC	P49674	CSNK1E	S2464	E2463D	2463	Missense	proximal	-1	no	27.851	25.690	EPSD	COSMIC	22.404	Down-regulation
CK1_CK1_CK1-D_CSNK1E_ST	P25054	APC	P49674	CSNK1E	S2473	S2466F	2466	Missense	distal	-7	no	31.375	31.372	EPSD	COSMIC	22.404	Down-regulation
CK1_CK1_CK1-D_CSNK1E_ST	P25054	APC	P49674	CSNK1E	S2473	P2467S	2467	Missense	distal	-6	no	31.375	32.032	EPSD	COSMIC;GDSC;CCLE	22.404	Up-regulation
CK1_CK1_CK1-D_CSNK1E_ST	P25054	APC	P49674	CSNK1E	S2473	P2467T	2467	Missense	distal	-6	no	31.375	31.675	EPSD	COSMIC	22.404	Up-regulation
CK1_CK1_CK1-D_CSNK1E_ST	P25054	APC	P49674	CSNK1E	S2473	R2470G	2470	Missense	distal	-3	no	31.375	33.489	EPSD	COSMIC	22.404	Up-regulation
CK1_CK1_CK1-D_CSNK1E_ST	P25054	APC	P49674	CSNK1E	S2473	R2470T	2470	Missense	distal	-3	no	31.375	31.319	EPSD	COSMIC	22.404	Down-regulation
CK1_CK1_CK1-D_CSNK1E_ST	P25054	APC	P49674	CSNK1E	S2473	T2475A	2475	Missense	proximal	2	no	31.375	33.203	EPSD	COSMIC	22.404	Up-regulation
CK1_CK1_CK1-D_CSNK1E_ST	P25054	APC	P49674	CSNK1E	S2473	R2470K	2470	Missense	distal	-3	no	31.375	31.929	EPSD	COSMIC	22.404	Up-regulation
CK1_CK1_CK1-D_CSNK1E_ST	P25054	APC	P49674	CSNK1E	S2473	A2479V	2479	Missense	distal	6	no	31.375	29.874	EPSD	COSMIC	22.404	Down-regulation
CK1_CK1_CK1-D_CSNK1E_ST	P25054	APC	P49674	CSNK1E	S2473	S2466Y	2466	Missense	distal	-7	no	31.375	31.370	EPSD	COSMIC	22.404	Down-regulation
CK1_CK1_CK1-D_CSNK1E_ST	P25054	APC	P49674	CSNK1E	S2473	S2473Y	2473	Missense	central	0	yes	31.375	0.000	EPSD	COSMIC	22.404	Loss
CK1_CK1_CK1-D_CSNK1E_ST	P25054	APC	P49674	CSNK1E	S2533	R2530W	2530	Missense	distal	-3	no	28.080	26.746	EPSD	COSMIC	22.404	Down-regulation
CK1_CK1_CK1-D_CSNK1E_ST	P25054	APC	P49674	CSNK1E	S2533	S2533F	2533	Missense	central	0	yes	28.080	0.000	EPSD	COSMIC	22.404	Loss
CK1_CK1_CK1-D_CSNK1E_ST	P25054	APC	P49674	CSNK1E	S2533	I2528V	2528	Missense	distal	-5	no	28.080	28.479	EPSD	COSMIC	22.404	Up-regulation
CK1_CK1_CK1-D_CSNK1E_ST	P25054	APC	P49674	CSNK1E	S2533	P2536S	2536	Missense	distal	3	no	28.080	29.062	EPSD	COSMIC	22.404	Up-regulation
CK1_CK1_CK1-D_CSNK1E_ST	P25054	APC	P49674	CSNK1E	S2533	D2527N	2527	Missense	distal	-6	no	28.080	28.549	EPSD	COSMIC	22.404	Up-regulation
CK1_CK1_CK1-D_CSNK1E_ST	P25054	APC	P49674	CSNK1E	S2533	P2536T	2536	Missense	distal	3	no	28.080	23.923	EPSD	COSMIC	22.404	Down-regulation
CK1_CK1_CK1-D_CSNK1E_ST	P25054	APC	P49674	CSNK1E	S2535	R2530W	2530	Missense	distal	-5	no	26.508	25.698	EPSD	COSMIC	22.404	Down-regulation
CK1_CK1_CK1-D_CSNK1E_ST	P25054	APC	P49674	CSNK1E	S2535	S2533F	2533	Missense	proximal	-2	no	26.508	18.471	EPSD	COSMIC	22.404	Loss
CK1_CK1_CK1-D_CSNK1E_ST	P25054	APC	P49674	CSNK1E	S2535	I2528V	2528	Missense	distal	-7	no	26.508	26.505	EPSD	COSMIC	22.404	Down-regulation
CK1_CK1_CK1-D_CSNK1E_ST	P25054	APC	P49674	CSNK1E	S2535	P2536S	2536	Missense	proximal	1	no	26.508	26.805	EPSD	COSMIC	22.404	Up-regulation
CK1_CK1_CK1-D_CSNK1E_ST	P25054	APC	P49674	CSNK1E	S2535	N2542S	2542	Missense	distal	7	no	26.508	25.954	EPSD	COSMIC	22.404	Down-regulation
CK1_CK1_CK1-D_CSNK1E_ST	P25054	APC	P49674	CSNK1E	S2535	P2536T	2536	Missense	proximal	1	no	26.508	26.193	EPSD	COSMIC	22.404	Down-regulation
CK1_CK1_CK1-D_CSNK1E_ST	P25054	APC	P49674	CSNK1E	T2546	K2553E	2553	Missense	distal	7	no	24.642	24.287	EPSD	COSMIC	22.404	Down-regulation
CK1_CK1_CK1-D_CSNK1E_ST	P25054	APC	P49674	CSNK1E	T2546	T2546A	2546	Missense	central	0	yes	24.642	0.000	EPSD	COSMIC	22.404	Loss
CK1_CK1_CK1-D_CSNK1E_ST	P25054	APC	P49674	CSNK1E	T2546	N2542S	2542	Missense	distal	-4	no	24.642	30.176	EPSD	COSMIC	22.404	Up-regulation
CK1_CK1_CK1-D_CSNK1E_ST	P25054	APC	P49674	CSNK1E	T2546	K2553R	2553	Missense	distal	7	no	24.642	24.405	EPSD	COSMIC	22.404	Down-regulation
CK1_CK1_CK1-D_CSNK1E_ST	P25054	APC	P49674	CSNK1E	T2546	E2550Q	2550	Missense	distal	4	no	24.642	24.655	EPSD	COSMIC;GDSC;CCLE	22.404	Up-regulation
CK1_CK1_CK1-D_CSNK1E_ST	P25054	APC	P49674	CSNK1E	T2563	W2564C	2564	Missense	proximal	1	no	24.739	25.246	EPSD	COSMIC	22.404	Up-regulation
CK1_CK1_CK1-D_CSNK1E_ST	P25054	APC	P49674	CSNK1E	T2563	R2560Q	2560	Missense	distal	-3	no	24.739	24.578	EPSD	COSMIC	22.404	Down-regulation
CK1_CK1_CK1-D_CSNK1E_ST	P25054	APC	P49674	CSNK1E	T2563	L2558H	2558	Missense	distal	-5	no	24.739	24.248	EPSD	COSMIC	22.404	Down-regulation
CK1_CK1_CK1-D_CSNK1E_ST	P25054	APC	P49674	CSNK1E	T2563	R2565I	2565	Missense	proximal	2	no	24.739	28.062	EPSD	COSMIC	22.404	Up-regulation
CK1_CK1_CK1-D_CSNK1E_ST	P25054	APC	P49674	CSNK1E	T2563	S2562G	2562	Missense	proximal	-1	no	24.739	23.559	EPSD	COSMIC;CCLE	22.404	Down-regulation
CK1_CK1_CK1-D_CSNK1E_ST	P25054	APC	P49674	CSNK1E	T2563	R2565K	2565	Missense	proximal	2	no	24.739	26.305	EPSD	COSMIC	22.404	Up-regulation
CK1_CK1_CK1-D_CSNK1E_ST	P25054	APC	P49674	CSNK1E	T2563	R2566I	2566	Missense	distal	3	no	24.739	22.785	EPSD	COSMIC	22.404	Down-regulation
CK1_CK1_CK1-D_CSNK1E_ST	P25054	APC	P49674	CSNK1E	T2563	S2570L	2570	Missense	distal	7	no	24.739	25.328	EPSD	COSMIC	22.404	Up-regulation
CK1_CK1_CK1-D_CSNK1E_ST	P25054	APC	P49674	CSNK1E	T2563	S2562C	2562	Missense	proximal	-1	no	24.739	17.466	EPSD	COSMIC	22.404	Loss
CK1_CK1_CK1-D_CSNK1E_ST	P25054	APC	P49674	CSNK1E	T2563	S2569R	2569	Missense	distal	6	no	24.739	24.914	EPSD	COSMIC;GDSC;CCLE	22.404	Up-regulation
CK1_CK1_CK1-D_CSNK1E_ST	P25054	APC	P49674	CSNK1E	S2569	W2564C	2564	Missense	distal	-5	no	23.725	24.352	EPSD	COSMIC	22.404	Up-regulation
CK1_CK1_CK1-D_CSNK1E_ST	P25054	APC	P49674	CSNK1E	S2569	R2565I	2565	Missense	distal	-4	no	23.725	22.871	EPSD	COSMIC	22.404	Down-regulation
CK1_CK1_CK1-D_CSNK1E_ST	P25054	APC	P49674	CSNK1E	S2569	S2562G	2562	Missense	distal	-7	no	23.725	23.723	EPSD	COSMIC;CCLE	22.404	Down-regulation
CK1_CK1_CK1-D_CSNK1E_ST	P25054	APC	P49674	CSNK1E	S2569	R2565K	2565	Missense	distal	-4	no	23.725	21.459	EPSD	COSMIC	22.404	Loss
CK1_CK1_CK1-D_CSNK1E_ST	P25054	APC	P49674	CSNK1E	S2569	R2566I	2566	Missense	distal	-3	no	23.725	25.042	EPSD	COSMIC	22.404	Up-regulation
CK1_CK1_CK1-D_CSNK1E_ST	P25054	APC	P49674	CSNK1E	S2569	S2570L	2570	Missense	proximal	1	no	23.725	23.073	EPSD	COSMIC	22.404	Down-regulation
CK1_CK1_CK1-D_CSNK1E_ST	P25054	APC	P49674	CSNK1E	S2569	S2562C	2562	Missense	distal	-7	no	23.725	23.722	EPSD	COSMIC	22.404	Down-regulation
CK1_CK1_CK1-D_CSNK1E_ST	P25054	APC	P49674	CSNK1E	S2569	I2573V	2573	Missense	distal	4	no	23.725	23.860	EPSD	COSMIC	22.404	Up-regulation
CK1_CK1_CK1-D_CSNK1E_ST	P25054	APC	P49674	CSNK1E	S2569	S2569R	2569	Missense	central	0	yes	23.725	0.000	EPSD	COSMIC;GDSC;CCLE	22.404	Loss
CK1_CK1_CK1-D_CSNK1E_ST	P25054	APC	P49674	CSNK1E	S2577	S2577L	2577	Missense	central	0	yes	25.007	0.000	EPSD	COSMIC	22.404	Loss
CK1_CK1_CK1-D_CSNK1E_ST	P25054	APC	P49674	CSNK1E	S2577	S2581N	2581	Missense	distal	4	no	25.007	25.099	EPSD	COSMIC	22.404	Up-regulation
CK1_CK1_CK1-D_CSNK1E_ST	P25054	APC	P49674	CSNK1E	S2577	S2570L	2570	Missense	distal	-7	no	25.007	25.002	EPSD	COSMIC	22.404	Down-regulation
CK1_CK1_CK1-D_CSNK1E_ST	P25054	APC	P49674	CSNK1E	S2577	I2573V	2573	Missense	distal	-4	no	25.007	24.837	EPSD	COSMIC	22.404	Down-regulation
CK1_CK1_CK1-D_CSNK1E_ST	P25054	APC	P49674	CSNK1E	S2580	S2577L	2577	Missense	distal	-3	no	32.695	29.509	EPSD	COSMIC	22.404	Down-regulation
CK1_CK1_CK1-D_CSNK1E_ST	P25054	APC	P49674	CSNK1E	S2580	S2581N	2581	Missense	proximal	1	no	32.695	32.366	EPSD	COSMIC	22.404	Down-regulation
CK1_CK1_CK1-D_CSNK1E_ST	P25054	APC	P49674	CSNK1E	S2580	I2573V	2573	Missense	distal	-7	no	32.695	32.692	EPSD	COSMIC	22.404	Down-regulation
CK1_CK1_CK1-D_CSNK1E_ST	P25054	APC	P49674	CSNK1E	S2580	E2587K	2587	Missense	distal	7	no	32.695	33.050	EPSD	COSMIC	22.404	Up-regulation
CK1_CK1_CK1-D_CSNK1E_ST	P25054	APC	P49674	CSNK1E	S2594	K2599N	2599	Missense	distal	5	no	22.380	22.530	EPSD	COSMIC	22.404	Gain
CK1_CK1_CK1-D_CSNK1E_ST	P25054	APC	P49674	CSNK1E	S2632	Q2628H	2628	Missense	distal	-4	no	31.939	29.999	EPSD	COSMIC	22.404	Down-regulation
CK1_CK1_CK1-D_CSNK1E_ST	P25054	APC	P49674	CSNK1E	S2632	G2637C	2637	Missense	distal	5	no	31.939	31.599	EPSD	COSMIC	22.404	Down-regulation
CK1_CK1_CK1-D_CSNK1E_ST	P25054	APC	P49674	CSNK1E	S2632	G2633S	2633	Missense	proximal	1	no	31.939	32.918	EPSD	COSMIC	22.404	Up-regulation
CK1_CK1_CK1-D_CSNK1E_ST	P25054	APC	P49674	CSNK1E	S2632	S2631F	2631	Missense	proximal	-1	no	31.939	24.233	EPSD	COSMIC	22.404	Down-regulation
CK1_CK1_CK1-D_CSNK1E_ST	P25054	APC	P49674	CSNK1E	S2632	A2638S	2638	Missense	distal	6	no	31.939	35.638	EPSD	COSMIC;GDSC;CCLE	22.404	Up-regulation
CK1_CK1_CK1-D_CSNK1E_ST	P25054	APC	P49674	CSNK1E	S2632	S2627F	2627	Missense	distal	-5	no	31.939	30.220	EPSD	COSMIC	22.404	Down-regulation
CK1_CK1_CK1-D_CSNK1E_ST	P25054	APC	P49674	CSNK1E	S2632	S2625N	2625	Missense	distal	-7	no	31.939	31.936	EPSD	COSMIC	22.404	Down-regulation
CK1_CK1_CK1-D_CSNK1E_ST	P25054	APC	P49674	CSNK1E	S2765	S2766N	2766	Missense	proximal	1	no	33.220	32.891	EPSD	COSMIC	22.404	Down-regulation
CK1_CK1_CK1-D_CSNK1E_ST	P25054	APC	P49674	CSNK1E	S2765	S2772P	2772	Missense	distal	7	no	33.220	33.424	EPSD	COSMIC	22.404	Up-regulation
CK1_CK1_CK1-D_CSNK1E_ST	P25054	APC	P49674	CSNK1E	S2765	S2763N	2763	Missense	proximal	-2	no	33.220	26.108	EPSD	COSMIC	22.404	Down-regulation
CK1_CK1_CK1-D_CSNK1E_ST	P25054	APC	P49674	CSNK1E	S2765	T2760A	2760	Missense	distal	-5	no	33.220	33.883	EPSD	COSMIC	22.404	Up-regulation
CK1_CK1_CK1-D_CSNK1E_ST	P25054	APC	P49674	CSNK1E	S2765	S2764Y	2764	Missense	proximal	-1	no	33.220	27.191	EPSD	COSMIC	22.404	Down-regulation
CK1_CK1_CK1-D_CSNK1E_ST	P25054	APC	P49674	CSNK1E	S2767	S2766N	2766	Missense	proximal	-1	no	29.400	22.618	EPSD	COSMIC	22.404	Down-regulation
CK1_CK1_CK1-D_CSNK1E_ST	P25054	APC	P49674	CSNK1E	S2767	S2772P	2772	Missense	distal	5	no	29.400	29.693	EPSD	COSMIC	22.404	Up-regulation
CK1_CK1_CK1-D_CSNK1E_ST	P25054	APC	P49674	CSNK1E	S2767	S2763N	2763	Missense	distal	-4	no	29.400	23.866	EPSD	COSMIC	22.404	Down-regulation
CK1_CK1_CK1-D_CSNK1E_ST	P25054	APC	P49674	CSNK1E	S2767	T2760A	2760	Missense	distal	-7	no	29.400	29.397	EPSD	COSMIC	22.404	Down-regulation
CK1_CK1_CK1-D_CSNK1E_ST	P25054	APC	P49674	CSNK1E	S2767	S2764Y	2764	Missense	distal	-3	no	29.400	25.170	EPSD	COSMIC	22.404	Down-regulation
CK1_CK1_CK1-D_CSNK1E_ST	P25054	APC	P49674	CSNK1E	S2768	S2766N	2766	Missense	proximal	-2	no	27.070	19.958	EPSD	COSMIC	22.404	Loss
CK1_CK1_CK1-D_CSNK1E_ST	P25054	APC	P49674	CSNK1E	S2768	S2772P	2772	Missense	distal	4	no	27.070	27.104	EPSD	COSMIC	22.404	Up-regulation
CK1_CK1_CK1-D_CSNK1E_ST	P25054	APC	P49674	CSNK1E	S2768	S2763N	2763	Missense	distal	-5	no	27.070	25.941	EPSD	COSMIC	22.404	Down-regulation
CK1_CK1_CK1-D_CSNK1E_ST	P25054	APC	P49674	CSNK1E	S2768	S2764Y	2764	Missense	distal	-4	no	27.070	21.929	EPSD	COSMIC	22.404	Loss
CK1_CK1_CK1-D_CSNK1E_ST	P25054	APC	P49674	CSNK1E	S2772	S2766N	2766	Missense	distal	-6	no	23.426	22.993	EPSD	COSMIC	22.404	Down-regulation
CK1_CK1_CK1-D_CSNK1E_ST	P25054	APC	P49674	CSNK1E	S2772	S2772P	2772	Missense	central	0	yes	23.426	0.000	EPSD	COSMIC	22.404	Loss
CK1_CK1_CK1-D_CSNK1E_ST	P25054	APC	P49674	CSNK1E	T2776	V2781A	2781	Missense	distal	5	no	25.531	24.614	EPSD	COSMIC	22.404	Down-regulation
CK1_CK1_CK1-D_CSNK1E_ST	P25054	APC	P49674	CSNK1E	T2776	S2772P	2772	Missense	distal	-4	no	25.531	23.716	EPSD	COSMIC	22.404	Down-regulation
CK1_CK1_CK1-D_CSNK1E_ST	P25054	APC	P49674	CSNK1E	T2776	V2781M	2781	Missense	distal	5	no	25.531	24.322	EPSD	COSMIC	22.404	Down-regulation
CK1_CK1_CK1-D_CSNK1E_ST	P25054	APC	P49674	CSNK1E	S2793	D2796N	2796	Missense	distal	3	no	26.193	20.098	EPSD	COSMIC	22.404	Loss
CK1_CK1_CK1-D_CSNK1E_ST	P25054	APC	P49674	CSNK1E	S2793	P2790L	2790	Missense	distal	-3	no	26.193	22.573	EPSD	COSMIC	22.404	Down-regulation
CK1_CK1_CK1-D_CSNK1E_ST	P25054	APC	P49674	CSNK1E	S2793	S2793G	2793	Missense	central	0	yes	26.193	0.000	EPSD	COSMIC	22.404	Loss
CK1_CK1_CK1-D_CSNK1E_ST	P25054	APC	P49674	CSNK1E	S2793	S2789I	2789	Missense	distal	-4	no	26.193	21.854	EPSD	COSMIC	22.404	Loss
CK1_CK1_CK1-D_CSNK1E_ST	P25054	APC	P49674	CSNK1E	S2793	N2787S	2787	Missense	distal	-6	no	26.193	26.626	EPSD	COSMIC	22.404	Up-regulation
CK1_CK1_CK1-D_CSNK1E_ST	P25054	APC	P49674	CSNK1E	S2793	T2798A	2798	Missense	distal	5	no	26.193	26.741	EPSD	COSMIC	22.404	Up-regulation
CK1_CK1_CK1-D_CSNK1E_ST	P25054	APC	P49674	CSNK1E	S2793	K2792R	2792	Missense	proximal	-1	no	26.193	22.966	EPSD	COSMIC	22.404	Down-regulation
CK1_CK1_CK1-D_CSNK1E_ST	P25054	APC	P49674	CSNK1E	S2793	D2796G	2796	Missense	distal	3	no	26.193	22.706	EPSD	COSMIC;GDSC;CCLE	22.404	Down-regulation
CK1_CK1_CK1-D_CSNK1E_ST	P25054	APC	P49674	CSNK1E	S2793	R2791S	2791	Missense	proximal	-2	no	26.193	33.101	EPSD	COSMIC	22.404	Up-regulation
CK1_CK1_CK1-D_CSNK1E_ST	P25054	APC	P49674	CSNK1E	S2797	D2796N	2796	Missense	proximal	-1	no	31.982	26.889	EPSD	COSMIC	22.404	Down-regulation
CK1_CK1_CK1-D_CSNK1E_ST	P25054	APC	P49674	CSNK1E	S2797	P2790L	2790	Missense	distal	-7	no	31.982	31.978	EPSD	COSMIC	22.404	Down-regulation
CK1_CK1_CK1-D_CSNK1E_ST	P25054	APC	P49674	CSNK1E	S2797	S2803P	2803	Missense	distal	6	no	31.982	32.620	EPSD	COSMIC	22.404	Up-regulation
CK1_CK1_CK1-D_CSNK1E_ST	P25054	APC	P49674	CSNK1E	S2797	S2793G	2793	Missense	distal	-4	no	31.982	27.695	EPSD	COSMIC	22.404	Down-regulation
CK1_CK1_CK1-D_CSNK1E_ST	P25054	APC	P49674	CSNK1E	S2797	T2798A	2798	Missense	proximal	1	no	31.982	32.306	EPSD	COSMIC	22.404	Up-regulation
CK1_CK1_CK1-D_CSNK1E_ST	P25054	APC	P49674	CSNK1E	S2797	K2792R	2792	Missense	distal	-5	no	31.982	32.168	EPSD	COSMIC	22.404	Up-regulation
CK1_CK1_CK1-D_CSNK1E_ST	P25054	APC	P49674	CSNK1E	S2797	D2796G	2796	Missense	proximal	-1	no	31.982	32.492	EPSD	COSMIC;GDSC;CCLE	22.404	Up-regulation
CK1_CK1_CK1-D_CSNK1E_ST	P25054	APC	P49674	CSNK1E	S2797	R2791S	2791	Missense	distal	-6	no	31.982	33.307	EPSD	COSMIC	22.404	Up-regulation
CK1_CK1_CK1-D_CSNK1E_ST	P25054	APC	P49674	CSNK1E	T2798	D2796N	2796	Missense	proximal	-2	no	23.150	20.072	EPSD	COSMIC	22.404	Loss
CK1_CK1_CK1-D_CSNK1E_ST	P25054	APC	P49674	CSNK1E	T2798	S2803P	2803	Missense	distal	5	no	23.150	23.443	EPSD	COSMIC	22.404	Up-regulation
CK1_CK1_CK1-D_CSNK1E_ST	P25054	APC	P49674	CSNK1E	T2798	S2793G	2793	Missense	distal	-5	no	23.150	22.784	EPSD	COSMIC	22.404	Down-regulation
CK1_CK1_CK1-D_CSNK1E_ST	P25054	APC	P49674	CSNK1E	T2798	T2798A	2798	Missense	central	0	yes	23.150	0.000	EPSD	COSMIC	22.404	Loss
CK1_CK1_CK1-D_CSNK1E_ST	P25054	APC	P49674	CSNK1E	T2798	K2792R	2792	Missense	distal	-6	no	23.150	22.013	EPSD	COSMIC	22.404	Loss
CK1_CK1_CK1-D_CSNK1E_ST	P25054	APC	P49674	CSNK1E	T2798	D2796G	2796	Missense	proximal	-2	no	23.150	24.982	EPSD	COSMIC;GDSC;CCLE	22.404	Up-regulation
CK1_CK1_CK1-D_CSNK1E_ST	P25054	APC	P49674	CSNK1E	T2798	R2791S	2791	Missense	distal	-7	no	23.150	23.157	EPSD	COSMIC	22.404	Up-regulation
CK1_CK1_CK1-D_CSNK1E_ST	P25054	APC	P49674	CSNK1E	S2799	T2798A	2798	Missense	proximal	-1	no	19.222	24.998	EPSD	COSMIC	22.404	Gain
CK1_CK1_CK1-D_CSNK1E_ST	P25054	APC	P49674	CSNK1E	S2825	T2820I	2820	Missense	distal	-5	no	22.865	23.174	EPSD	COSMIC	22.404	Up-regulation
CK1_CK1_CK1-D_CSNK1E_ST	P25054	APC	P49674	CSNK1E	S2825	S2825F	2825	Missense	central	0	yes	22.865	0.000	EPSD	COSMIC	22.404	Loss
CK1_CK1_CK1-D_CSNK1E_ST	P25054	APC	P49674	CSNK1E	S2825	D2821G	2821	Missense	distal	-4	no	22.865	20.350	EPSD	COSMIC	22.404	Loss
CK1_CK1_CK1-D_CSNK1E_ST	P25054	APC	P49674	CSNK1E	S2825	S2822N	2822	Missense	distal	-3	no	22.865	20.600	EPSD	COSMIC	22.404	Loss
CK1_CK1_CK1-D_CSNK1E_ST	P25054	APC	P49674	CSNK1E	S2825	G2827E	2827	Missense	proximal	2	no	22.865	24.297	EPSD	COSMIC	22.404	Up-regulation
CK1_CK1_CK1-D_CSNK1E_ST	P25054	APC	P49674	CSNK1E	S2825	E2824Q	2824	Missense	proximal	-1	no	22.865	18.978	EPSD	COSMIC	22.404	Loss
CK1_CK1_CK1-D_CSNK1E_ST	P25054	APC	P49674	CSNK1E	S2826	T2820I	2820	Missense	distal	-6	no	24.690	25.221	EPSD	COSMIC	22.404	Up-regulation
CK1_CK1_CK1-D_CSNK1E_ST	P25054	APC	P49674	CSNK1E	S2826	S2825F	2825	Missense	proximal	-1	no	24.690	16.984	EPSD	COSMIC	22.404	Loss
CK1_CK1_CK1-D_CSNK1E_ST	P25054	APC	P49674	CSNK1E	S2826	D2821G	2821	Missense	distal	-5	no	24.690	25.232	EPSD	COSMIC	22.404	Up-regulation
CK1_CK1_CK1-D_CSNK1E_ST	P25054	APC	P49674	CSNK1E	S2826	S2822N	2822	Missense	distal	-4	no	24.690	19.156	EPSD	COSMIC	22.404	Loss
CK1_CK1_CK1-D_CSNK1E_ST	P25054	APC	P49674	CSNK1E	S2826	R2833C	2833	Missense	distal	7	no	24.690	24.752	EPSD	COSMIC	22.404	Up-regulation
CK1_CK1_CK1-D_CSNK1E_ST	P25054	APC	P49674	CSNK1E	S2826	R2833H	2833	Missense	distal	7	no	24.690	24.823	EPSD	COSMIC	22.404	Up-regulation
CK1_CK1_CK1-D_CSNK1E_ST	P25054	APC	P49674	CSNK1E	S2826	G2827E	2827	Missense	proximal	1	no	24.690	25.036	EPSD	COSMIC	22.404	Up-regulation
CK1_CK1_CK1-D_CSNK1E_ST	P25054	APC	P49674	CSNK1E	S2826	E2824Q	2824	Missense	proximal	-2	no	24.690	22.304	EPSD	COSMIC	22.404	Loss
CK1_CK1_CK1-D_CSNK1E_ST	P25054	APC	P49674	CSNK1E	T2828	S2825F	2825	Missense	distal	-3	no	26.711	24.275	EPSD	COSMIC	22.404	Down-regulation
CK1_CK1_CK1-D_CSNK1E_ST	P25054	APC	P49674	CSNK1E	T2828	D2821G	2821	Missense	distal	-7	no	26.711	26.710	EPSD	COSMIC	22.404	Down-regulation
CK1_CK1_CK1-D_CSNK1E_ST	P25054	APC	P49674	CSNK1E	T2828	S2822N	2822	Missense	distal	-6	no	26.711	26.278	EPSD	COSMIC	22.404	Down-regulation
CK1_CK1_CK1-D_CSNK1E_ST	P25054	APC	P49674	CSNK1E	T2828	R2833C	2833	Missense	distal	5	no	26.711	26.488	EPSD	COSMIC	22.404	Down-regulation
CK1_CK1_CK1-D_CSNK1E_ST	P25054	APC	P49674	CSNK1E	T2828	R2833H	2833	Missense	distal	5	no	26.711	26.136	EPSD	COSMIC	22.404	Down-regulation
CK1_CK1_CK1-D_CSNK1E_ST	P25054	APC	P49674	CSNK1E	T2828	G2827E	2827	Missense	proximal	-1	no	26.711	28.362	EPSD	COSMIC	22.404	Up-regulation
CK1_CK1_CK1-D_CSNK1E_ST	P25054	APC	P49674	CSNK1E	T2828	E2824Q	2824	Missense	distal	-4	no	26.711	25.161	EPSD	COSMIC	22.404	Down-regulation
CK1_CK1_CK1-D_CSNK1E_ST	P35222	CTNNB1	P49674	CSNK1E	T41	S45T	45	Missense	distal	4	no	35.952	36.025	EPSD	COSMIC	22.404	Up-regulation
CK1_CK1_CK1-D_CSNK1E_ST	P35222	CTNNB1	P49674	CSNK1E	T41	P44S	44	Missense	distal	3	no	35.952	36.934	EPSD	COSMIC	22.404	Up-regulation
CK1_CK1_CK1-D_CSNK1E_ST	P35222	CTNNB1	P49674	CSNK1E	T41	A43V	43	Missense	proximal	2	no	35.952	33.786	EPSD	COSMIC	22.404	Down-regulation
CK1_CK1_CK1-D_CSNK1E_ST	P35222	CTNNB1	P49674	CSNK1E	T41	G48D	48	Missense	distal	7	no	35.952	35.908	EPSD	COSMIC	22.404	Down-regulation
CK1_CK1_CK1-D_CSNK1E_ST	P35222	CTNNB1	P49674	CSNK1E	T41	A39G	39	Missense	proximal	-2	no	35.952	32.892	EPSD	COSMIC	22.404	Down-regulation
CK1_CK1_CK1-D_CSNK1E_ST	P35222	CTNNB1	P49674	CSNK1E	T41	G38A	38	Missense	distal	-3	no	35.952	34.164	EPSD	COSMIC	22.404	Down-regulation
CK1_CK1_CK1-D_CSNK1E_ST	P35222	CTNNB1	P49674	CSNK1E	T41	T40I	40	Missense	proximal	-1	no	35.952	36.817	EPSD	COSMIC	22.404	Up-regulation
CK1_CK1_CK1-D_CSNK1E_ST	P35222	CTNNB1	P49674	CSNK1E	T41	P44A	44	Missense	distal	3	no	35.952	30.774	EPSD	COSMIC	22.404	Down-regulation
CK1_CK1_CK1-D_CSNK1E_ST	P35222	CTNNB1	P49674	CSNK1E	T41	I35T	35	Missense	distal	-6	no	35.952	35.421	EPSD	COSMIC	22.404	Down-regulation
CK1_CK1_CK1-D_CSNK1E_ST	P35222	CTNNB1	P49674	CSNK1E	T41	T41P	41	Missense	central	0	yes	35.952	0.000	EPSD	COSMIC	22.404	Loss
CK1_CK1_CK1-D_CSNK1E_ST	P35222	CTNNB1	P49674	CSNK1E	T41	T42R	42	Missense	proximal	1	no	35.952	35.831	EPSD	COSMIC	22.404	Down-regulation
CK1_CK1_CK1-D_CSNK1E_ST	P35222	CTNNB1	P49674	CSNK1E	T41	S45A	45	Missense	distal	4	no	35.952	35.997	EPSD	COSMIC	22.404	Up-regulation
CK1_CK1_CK1-D_CSNK1E_ST	P35222	CTNNB1	P49674	CSNK1E	T41	H36R	36	Missense	distal	-5	no	35.952	36.574	EPSD	COSMIC	22.404	Up-regulation
CK1_CK1_CK1-D_CSNK1E_ST	P35222	CTNNB1	P49674	CSNK1E	T41	G48S	48	Missense	distal	7	no	35.952	35.748	EPSD	COSMIC	22.404	Down-regulation
CK1_CK1_CK1-D_CSNK1E_ST	P35222	CTNNB1	P49674	CSNK1E	T41	T40A	40	Missense	proximal	-1	no	35.952	41.727	EPSD	COSMIC	22.404	Up-regulation
CK1_CK1_CK1-D_CSNK1E_ST	P35222	CTNNB1	P49674	CSNK1E	T41	A43T	43	Missense	proximal	2	no	35.952	34.125	EPSD	COSMIC	22.404	Down-regulation
CK1_CK1_CK1-D_CSNK1E_ST	P35222	CTNNB1	P49674	CSNK1E	T41	P44L	44	Missense	distal	3	no	35.952	30.131	EPSD	COSMIC	22.404	Down-regulation
CK1_CK1_CK1-D_CSNK1E_ST	P35222	CTNNB1	P49674	CSNK1E	T41	G34L	34	Missense	distal	-7	no	35.952	35.949	EPSD	COSMIC	22.404	Down-regulation
CK1_CK1_CK1-D_CSNK1E_ST	P35222	CTNNB1	P49674	CSNK1E	T41	T42I	42	Missense	proximal	1	no	35.952	36.535	EPSD	COSMIC	22.404	Up-regulation
CK1_CK1_CK1-D_CSNK1E_ST	P35222	CTNNB1	P49674	CSNK1E	T41	T42S	42	Missense	proximal	1	no	35.952	36.564	EPSD	COSMIC	22.404	Up-regulation
CK1_CK1_CK1-D_CSNK1E_ST	P35222	CTNNB1	P49674	CSNK1E	T41	T42K	42	Missense	proximal	1	no	35.952	36.041	EPSD	COSMIC	22.404	Up-regulation
CK1_CK1_CK1-D_CSNK1E_ST	P35222	CTNNB1	P49674	CSNK1E	T41	S47G	47	Missense	distal	6	no	35.952	33.436	EPSD	COSMIC	22.404	Down-regulation
CK1_CK1_CK1-D_CSNK1E_ST	P35222	CTNNB1	P49674	CSNK1E	T41	G48V	48	Missense	distal	7	no	35.952	36.647	EPSD	COSMIC	22.404	Up-regulation
CK1_CK1_CK1-D_CSNK1E_ST	P35222	CTNNB1	P49674	CSNK1E	T41	S47N	47	Missense	distal	6	no	35.952	32.760	EPSD	COSMIC	22.404	Down-regulation
CK1_CK1_CK1-D_CSNK1E_ST	P35222	CTNNB1	P49674	CSNK1E	T41	S37L	37	Missense	distal	-4	no	35.952	27.660	EPSD	COSMIC	22.404	Down-regulation
CK1_CK1_CK1-D_CSNK1E_ST	P35222	CTNNB1	P49674	CSNK1E	T41	A39T	39	Missense	proximal	-2	no	35.952	32.305	EPSD	COSMIC	22.404	Down-regulation
CK1_CK1_CK1-D_CSNK1E_ST	P35222	CTNNB1	P49674	CSNK1E	T41	H36Y	36	Missense	distal	-5	no	35.952	36.266	EPSD	COSMIC	22.404	Up-regulation
CK1_CK1_CK1-D_CSNK1E_ST	P35222	CTNNB1	P49674	CSNK1E	T41	A43P	43	Missense	proximal	2	no	35.952	31.715	EPSD	COSMIC	22.404	Down-regulation
CK1_CK1_CK1-D_CSNK1E_ST	P35222	CTNNB1	P49674	CSNK1E	T41	L46P	46	Missense	distal	5	no	35.952	34.960	EPSD	COSMIC	22.404	Down-regulation
CK1_CK1_CK1-D_CSNK1E_ST	P35222	CTNNB1	P49674	CSNK1E	T41	G38P	38	Missense	distal	-3	no	35.952	36.110	EPSD	COSMIC	22.404	Up-regulation
CK1_CK1_CK1-D_CSNK1E_ST	P35222	CTNNB1	P49674	CSNK1E	T41	G38D	38	Missense	distal	-3	no	35.952	35.849	EPSD	COSMIC	22.404	Down-regulation
CK1_CK1_CK1-D_CSNK1E_ST	P35222	CTNNB1	P49674	CSNK1E	T41	T42A	42	Missense	proximal	1	no	35.952	36.276	EPSD	COSMIC	22.404	Up-regulation
CK1_CK1_CK1-D_CSNK1E_ST	P35222	CTNNB1	P49674	CSNK1E	T41	L46V	46	Missense	distal	5	no	35.952	36.087	EPSD	COSMIC	22.404	Up-regulation
CK1_CK1_CK1-D_CSNK1E_ST	P35222	CTNNB1	P49674	CSNK1E	T41	S47L	47	Missense	distal	6	no	35.952	32.795	EPSD	COSMIC	22.404	Down-regulation
CK1_CK1_CK1-D_CSNK1E_ST	P35222	CTNNB1	P49674	CSNK1E	T41	I35M	35	Missense	distal	-6	no	35.952	35.738	EPSD	COSMIC	22.404	Down-regulation
CK1_CK1_CK1-D_CSNK1E_ST	P35222	CTNNB1	P49674	CSNK1E	T41	T40S	40	Missense	proximal	-1	no	35.952	38.053	EPSD	COSMIC	22.404	Up-regulation
CK1_CK1_CK1-D_CSNK1E_ST	P35222	CTNNB1	P49674	CSNK1E	T41	L46M	46	Missense	distal	5	no	35.952	34.877	EPSD	COSMIC	22.404	Down-regulation
CK1_CK1_CK1-D_CSNK1E_ST	P35222	CTNNB1	P49674	CSNK1E	T41	G34A	34	Missense	distal	-7	no	35.952	35.951	EPSD	COSMIC	22.404	Down-regulation
CK1_CK1_CK1-D_CSNK1E_ST	P35222	CTNNB1	P49674	CSNK1E	T41	S47T	47	Missense	distal	6	no	35.952	31.367	EPSD	COSMIC	22.404	Down-regulation
CK1_CK1_CK1-D_CSNK1E_ST	P35222	CTNNB1	P49674	CSNK1E	T41	G34I	34	Missense	distal	-7	no	35.952	35.954	EPSD	COSMIC	22.404	Up-regulation
CK1_CK1_CK1-D_CSNK1E_ST	P35222	CTNNB1	P49674	CSNK1E	T41	I35N	35	Missense	distal	-6	no	35.952	35.345	EPSD	COSMIC	22.404	Down-regulation
CK1_CK1_CK1-D_CSNK1E_ST	P35222	CTNNB1	P49674	CSNK1E	T41	T42Q	42	Missense	proximal	1	no	35.952	35.442	EPSD	COSMIC	22.404	Down-regulation
CK1_CK1_CK1-D_CSNK1E_ST	P35222	CTNNB1	P49674	CSNK1E	T41	S47C	47	Missense	distal	6	no	35.952	30.790	EPSD	COSMIC	22.404	Down-regulation
CK1_CK1_CK1-D_CSNK1E_ST	P35222	CTNNB1	P49674	CSNK1E	T41	S47R	47	Missense	distal	6	no	35.952	36.128	EPSD	COSMIC	22.404	Up-regulation
CK1_CK1_CK1-D_CSNK1E_ST	P35222	CTNNB1	P49674	CSNK1E	T41	A39V	39	Missense	proximal	-2	no	35.952	33.966	EPSD	COSMIC	22.404	Down-regulation
CK1_CK1_CK1-D_CSNK1E_ST	P35222	CTNNB1	P49674	CSNK1E	T41	S45E	45	Missense	distal	4	no	35.952	36.115	EPSD	COSMIC	22.404	Up-regulation
CK1_CK1_CK1-D_CSNK1E_ST	P35222	CTNNB1	P49674	CSNK1E	T41	G34D	34	Missense	distal	-7	no	35.952	35.953	EPSD	COSMIC	22.404	Up-regulation
CK1_CK1_CK1-D_CSNK1E_ST	P35222	CTNNB1	P49674	CSNK1E	T41	S37T	37	Missense	distal	-4	no	35.952	34.311	EPSD	COSMIC	22.404	Down-regulation
CK1_CK1_CK1-D_CSNK1E_ST	P35222	CTNNB1	P49674	CSNK1E	T41	I35K	35	Missense	distal	-6	no	35.952	35.591	EPSD	COSMIC	22.404	Down-regulation
CK1_CK1_CK1-D_CSNK1E_ST	P35222	CTNNB1	P49674	CSNK1E	T41	S45N	45	Missense	distal	4	no	35.952	36.044	EPSD	COSMIC	22.404	Up-regulation
CK1_CK1_CK1-D_CSNK1E_ST	P35222	CTNNB1	P49674	CSNK1E	T41	G38X	38	Missense	distal	-3	no	35.952	33.441	EPSD	COSMIC	22.404	Down-regulation
CK1_CK1_CK1-D_CSNK1E_ST	P35222	CTNNB1	P49674	CSNK1E	T41	L46Q	46	Missense	distal	5	no	35.952	34.464	EPSD	COSMIC	22.404	Down-regulation
CK1_CK1_CK1-D_CSNK1E_ST	P35222	CTNNB1	P49674	CSNK1E	T41	I35V	35	Missense	distal	-6	no	35.952	34.380	EPSD	COSMIC	22.404	Down-regulation
CK1_CK1_CK1-D_CSNK1E_ST	P35222	CTNNB1	P49674	CSNK1E	T41	S45X	45	Missense	distal	4	no	35.952	36.073	EPSD	COSMIC	22.404	Up-regulation
CK1_CK1_CK1-D_CSNK1E_ST	P35222	CTNNB1	P49674	CSNK1E	T41	G34C	34	Missense	distal	-7	no	35.952	35.951	EPSD	COSMIC	22.404	Down-regulation
CK1_CK1_CK1-D_CSNK1E_ST	P35222	CTNNB1	P49674	CSNK1E	T41	G38S	38	Missense	distal	-3	no	35.952	35.676	EPSD	COSMIC	22.404	Down-regulation
CK1_CK1_CK1-D_CSNK1E_ST	P35222	CTNNB1	P49674	CSNK1E	T41	S37V	37	Missense	distal	-4	no	35.952	31.443	EPSD	COSMIC	22.404	Down-regulation
CK1_CK1_CK1-D_CSNK1E_ST	P35222	CTNNB1	P49674	CSNK1E	T41	P44I	44	Missense	distal	3	no	35.952	32.936	EPSD	COSMIC	22.404	Down-regulation
CK1_CK1_CK1-D_CSNK1E_ST	P35222	CTNNB1	P49674	CSNK1E	T41	I35F	35	Missense	distal	-6	no	35.952	34.628	EPSD	COSMIC	22.404	Down-regulation
CK1_CK1_CK1-D_CSNK1E_ST	P35222	CTNNB1	P49674	CSNK1E	T41	S47I	47	Missense	distal	6	no	35.952	32.352	EPSD	COSMIC	22.404	Down-regulation
CK1_CK1_CK1-D_CSNK1E_ST	P35222	CTNNB1	P49674	CSNK1E	T41	S47Y	47	Missense	distal	6	no	35.952	31.724	EPSD	COSMIC	22.404	Down-regulation
CK1_CK1_CK1-D_CSNK1E_ST	P35222	CTNNB1	P49674	CSNK1E	T41	T40P	40	Missense	proximal	-1	no	35.952	37.148	EPSD	COSMIC	22.404	Up-regulation
CK1_CK1_CK1-D_CSNK1E_ST	P35222	CTNNB1	P49674	CSNK1E	S45	P44S	44	Missense	proximal	-1	no	38.292	39.196	PhosphoSitePlus	COSMIC	22.404	Up-regulation
CK1_CK1_CK1-D_CSNK1E_ST	P35222	CTNNB1	P49674	CSNK1E	S45	A43V	43	Missense	proximal	-2	no	38.292	36.305	PhosphoSitePlus	COSMIC	22.404	Down-regulation
CK1_CK1_CK1-D_CSNK1E_ST	P35222	CTNNB1	P49674	CSNK1E	S45	G48D	48	Missense	distal	3	no	38.292	41.778	PhosphoSitePlus	COSMIC	22.404	Up-regulation
CK1_CK1_CK1-D_CSNK1E_ST	P35222	CTNNB1	P49674	CSNK1E	S45	A39G	39	Missense	distal	-6	no	38.292	37.890	PhosphoSitePlus	COSMIC	22.404	Down-regulation
CK1_CK1_CK1-D_CSNK1E_ST	P35222	CTNNB1	P49674	CSNK1E	S45	N51T	51	Missense	distal	6	no	38.292	36.899	PhosphoSitePlus	COSMIC	22.404	Down-regulation
CK1_CK1_CK1-D_CSNK1E_ST	P35222	CTNNB1	P49674	CSNK1E	S45	P52L	52	Missense	distal	7	no	38.292	38.677	PhosphoSitePlus	COSMIC	22.404	Up-regulation
CK1_CK1_CK1-D_CSNK1E_ST	P35222	CTNNB1	P49674	CSNK1E	S45	N51S	51	Missense	distal	6	no	38.292	41.484	PhosphoSitePlus	COSMIC	22.404	Up-regulation
CK1_CK1_CK1-D_CSNK1E_ST	P35222	CTNNB1	P49674	CSNK1E	S45	G38A	38	Missense	distal	-7	no	38.292	38.291	PhosphoSitePlus	COSMIC	22.404	Down-regulation
CK1_CK1_CK1-D_CSNK1E_ST	P35222	CTNNB1	P49674	CSNK1E	S45	T40I	40	Missense	distal	-5	no	38.292	38.601	PhosphoSitePlus	COSMIC	22.404	Up-regulation
CK1_CK1_CK1-D_CSNK1E_ST	P35222	CTNNB1	P49674	CSNK1E	S45	P44A	44	Missense	proximal	-1	no	38.292	42.871	PhosphoSitePlus	COSMIC	22.404	Up-regulation
CK1_CK1_CK1-D_CSNK1E_ST	P35222	CTNNB1	P49674	CSNK1E	S45	T41P	41	Missense	distal	-4	no	38.292	38.117	PhosphoSitePlus	COSMIC	22.404	Down-regulation
CK1_CK1_CK1-D_CSNK1E_ST	P35222	CTNNB1	P49674	CSNK1E	S45	K49R	49	Missense	distal	4	no	38.292	38.449	PhosphoSitePlus	COSMIC	22.404	Up-regulation
CK1_CK1_CK1-D_CSNK1E_ST	P35222	CTNNB1	P49674	CSNK1E	S45	T42R	42	Missense	distal	-3	no	38.292	38.348	PhosphoSitePlus	COSMIC	22.404	Up-regulation
CK1_CK1_CK1-D_CSNK1E_ST	P35222	CTNNB1	P49674	CSNK1E	S45	S45A	45	Missense	central	0	yes	38.292	0.000	PhosphoSitePlus	COSMIC	22.404	Loss
CK1_CK1_CK1-D_CSNK1E_ST	P35222	CTNNB1	P49674	CSNK1E	S45	G48S	48	Missense	distal	3	no	38.292	40.993	PhosphoSitePlus	COSMIC	22.404	Up-regulation
CK1_CK1_CK1-D_CSNK1E_ST	P35222	CTNNB1	P49674	CSNK1E	S45	T40A	40	Missense	distal	-5	no	38.292	38.955	PhosphoSitePlus	COSMIC	22.404	Up-regulation
CK1_CK1_CK1-D_CSNK1E_ST	P35222	CTNNB1	P49674	CSNK1E	S45	A43T	43	Missense	proximal	-2	no	38.292	34.644	PhosphoSitePlus	COSMIC	22.404	Down-regulation
CK1_CK1_CK1-D_CSNK1E_ST	P35222	CTNNB1	P49674	CSNK1E	S45	P44L	44	Missense	proximal	-1	no	38.292	30.889	PhosphoSitePlus	COSMIC	22.404	Down-regulation
CK1_CK1_CK1-D_CSNK1E_ST	P35222	CTNNB1	P49674	CSNK1E	S45	T42I	42	Missense	distal	-3	no	38.292	39.666	PhosphoSitePlus	COSMIC	22.404	Up-regulation
CK1_CK1_CK1-D_CSNK1E_ST	P35222	CTNNB1	P49674	CSNK1E	S45	T42S	42	Missense	distal	-3	no	38.292	40.186	PhosphoSitePlus	COSMIC	22.404	Up-regulation
CK1_CK1_CK1-D_CSNK1E_ST	P35222	CTNNB1	P49674	CSNK1E	S45	T42K	42	Missense	distal	-3	no	38.292	38.902	PhosphoSitePlus	COSMIC	22.404	Up-regulation
CK1_CK1_CK1-D_CSNK1E_ST	P35222	CTNNB1	P49674	CSNK1E	S45	S47G	47	Missense	proximal	2	no	38.292	37.001	PhosphoSitePlus	COSMIC	22.404	Down-regulation
CK1_CK1_CK1-D_CSNK1E_ST	P35222	CTNNB1	P49674	CSNK1E	S45	G48V	48	Missense	distal	3	no	38.292	32.407	PhosphoSitePlus	COSMIC	22.404	Down-regulation
CK1_CK1_CK1-D_CSNK1E_ST	P35222	CTNNB1	P49674	CSNK1E	S45	S47N	47	Missense	proximal	2	no	38.292	37.017	PhosphoSitePlus	COSMIC	22.404	Down-regulation
CK1_CK1_CK1-D_CSNK1E_ST	P35222	CTNNB1	P49674	CSNK1E	S45	A39T	39	Missense	distal	-6	no	38.292	38.619	PhosphoSitePlus	COSMIC	22.404	Up-regulation
CK1_CK1_CK1-D_CSNK1E_ST	P35222	CTNNB1	P49674	CSNK1E	S45	K49T	49	Missense	distal	4	no	38.292	38.348	PhosphoSitePlus	COSMIC	22.404	Up-regulation
CK1_CK1_CK1-D_CSNK1E_ST	P35222	CTNNB1	P49674	CSNK1E	S45	G50D	50	Missense	distal	5	no	38.292	37.322	PhosphoSitePlus	COSMIC	22.404	Down-regulation
CK1_CK1_CK1-D_CSNK1E_ST	P35222	CTNNB1	P49674	CSNK1E	S45	A43P	43	Missense	proximal	-2	no	38.292	36.103	PhosphoSitePlus	COSMIC	22.404	Down-regulation
CK1_CK1_CK1-D_CSNK1E_ST	P35222	CTNNB1	P49674	CSNK1E	S45	L46P	46	Missense	proximal	1	no	38.292	38.647	PhosphoSitePlus	COSMIC	22.404	Up-regulation
CK1_CK1_CK1-D_CSNK1E_ST	P35222	CTNNB1	P49674	CSNK1E	S45	T42A	42	Missense	distal	-3	no	38.292	38.674	PhosphoSitePlus	COSMIC	22.404	Up-regulation
CK1_CK1_CK1-D_CSNK1E_ST	P35222	CTNNB1	P49674	CSNK1E	S45	L46V	46	Missense	proximal	1	no	38.292	38.627	PhosphoSitePlus	COSMIC	22.404	Up-regulation
CK1_CK1_CK1-D_CSNK1E_ST	P35222	CTNNB1	P49674	CSNK1E	S45	S47L	47	Missense	proximal	2	no	38.292	35.767	PhosphoSitePlus	COSMIC	22.404	Down-regulation
CK1_CK1_CK1-D_CSNK1E_ST	P35222	CTNNB1	P49674	CSNK1E	S45	T40S	40	Missense	distal	-5	no	38.292	39.600	PhosphoSitePlus	COSMIC	22.404	Up-regulation
CK1_CK1_CK1-D_CSNK1E_ST	P35222	CTNNB1	P49674	CSNK1E	S45	K49L	49	Missense	distal	4	no	38.292	38.420	PhosphoSitePlus	COSMIC	22.404	Up-regulation
CK1_CK1_CK1-D_CSNK1E_ST	P35222	CTNNB1	P49674	CSNK1E	S45	L46M	46	Missense	proximal	1	no	38.292	39.430	PhosphoSitePlus	COSMIC	22.404	Up-regulation
CK1_CK1_CK1-D_CSNK1E_ST	P35222	CTNNB1	P49674	CSNK1E	S45	S47T	47	Missense	proximal	2	no	38.292	39.126	PhosphoSitePlus	COSMIC	22.404	Up-regulation
CK1_CK1_CK1-D_CSNK1E_ST	P35222	CTNNB1	P49674	CSNK1E	S45	T41S	41	Missense	distal	-4	no	38.292	39.933	PhosphoSitePlus	COSMIC	22.404	Up-regulation
CK1_CK1_CK1-D_CSNK1E_ST	P35222	CTNNB1	P49674	CSNK1E	S45	T42Q	42	Missense	distal	-3	no	38.292	38.188	PhosphoSitePlus	COSMIC	22.404	Down-regulation
CK1_CK1_CK1-D_CSNK1E_ST	P35222	CTNNB1	P49674	CSNK1E	S45	S47C	47	Missense	proximal	2	no	38.292	36.489	PhosphoSitePlus	COSMIC	22.404	Down-regulation
CK1_CK1_CK1-D_CSNK1E_ST	P35222	CTNNB1	P49674	CSNK1E	S45	K49E	49	Missense	distal	4	no	38.292	38.438	PhosphoSitePlus	COSMIC	22.404	Up-regulation
CK1_CK1_CK1-D_CSNK1E_ST	P35222	CTNNB1	P49674	CSNK1E	S45	S47R	47	Missense	proximal	2	no	38.292	35.508	PhosphoSitePlus	COSMIC	22.404	Down-regulation
CK1_CK1_CK1-D_CSNK1E_ST	P35222	CTNNB1	P49674	CSNK1E	S45	A39V	39	Missense	distal	-6	no	38.292	37.578	PhosphoSitePlus	COSMIC	22.404	Down-regulation
CK1_CK1_CK1-D_CSNK1E_ST	P35222	CTNNB1	P49674	CSNK1E	S45	S45E	45	Missense	central	0	yes	38.292	0.000	PhosphoSitePlus	COSMIC	22.404	Loss
CK1_CK1_CK1-D_CSNK1E_ST	P35222	CTNNB1	P49674	CSNK1E	S45	G50S	50	Missense	distal	5	no	38.292	36.845	PhosphoSitePlus	COSMIC	22.404	Down-regulation
CK1_CK1_CK1-D_CSNK1E_ST	P35222	CTNNB1	P49674	CSNK1E	S45	S45N	45	Missense	central	0	yes	38.292	0.000	PhosphoSitePlus	COSMIC	22.404	Loss
CK1_CK1_CK1-D_CSNK1E_ST	P35222	CTNNB1	P49674	CSNK1E	S45	G38X	38	Missense	distal	-7	no	38.292	38.290	PhosphoSitePlus	COSMIC	22.404	Down-regulation
CK1_CK1_CK1-D_CSNK1E_ST	P35222	CTNNB1	P49674	CSNK1E	S45	L46Q	46	Missense	proximal	1	no	38.292	37.822	PhosphoSitePlus	COSMIC	22.404	Down-regulation
CK1_CK1_CK1-D_CSNK1E_ST	P35222	CTNNB1	P49674	CSNK1E	S45	S45X	45	Missense	central	0	yes	38.292	0.000	PhosphoSitePlus	COSMIC	22.404	Loss
CK1_CK1_CK1-D_CSNK1E_ST	P35222	CTNNB1	P49674	CSNK1E	S45	G38S	38	Missense	distal	-7	no	38.292	38.293	PhosphoSitePlus	COSMIC	22.404	Up-regulation
CK1_CK1_CK1-D_CSNK1E_ST	P35222	CTNNB1	P49674	CSNK1E	S45	P44I	44	Missense	proximal	-1	no	38.292	37.960	PhosphoSitePlus	COSMIC	22.404	Down-regulation
CK1_CK1_CK1-D_CSNK1E_ST	P35222	CTNNB1	P49674	CSNK1E	S45	S47I	47	Missense	proximal	2	no	38.292	38.831	PhosphoSitePlus	COSMIC	22.404	Up-regulation
CK1_CK1_CK1-D_CSNK1E_ST	P35222	CTNNB1	P49674	CSNK1E	S45	S47Y	47	Missense	proximal	2	no	38.292	38.123	PhosphoSitePlus	COSMIC	22.404	Down-regulation
CK1_CK1_CK1-D_CSNK1E_ST	P35222	CTNNB1	P49674	CSNK1E	S45	T40P	40	Missense	distal	-5	no	38.292	38.735	PhosphoSitePlus	COSMIC	22.404	Up-regulation
CK1_CK1_CK1-D_CSNK1E_ST	P35222	CTNNB1	P49674	CSNK1E	S73	G69A	69	Missense	distal	-4	no	18.299	23.478	EPSD	COSMIC	22.404	Gain
CK1_CK1_CK1-D_CSNK1E_ST	P35222	CTNNB1	P49674	CSNK1E	S250	M243T	243	Missense	distal	-7	no	24.069	24.074	EPSD	COSMIC	22.404	Up-regulation
CK1_CK1_CK1-D_CSNK1E_ST	P35222	CTNNB1	P49674	CSNK1E	S250	T257I	257	Missense	distal	7	no	24.069	23.876	EPSD	COSMIC	22.404	Down-regulation
CK1_CK1_CK1-D_CSNK1E_ST	P35222	CTNNB1	P49674	CSNK1E	S250	A255T	255	Missense	distal	5	no	24.069	23.521	EPSD	COSMIC	22.404	Down-regulation
CK1_CK1_CK1-D_CSNK1E_ST	P35222	CTNNB1	P49674	CSNK1E	S250	S246L	246	Missense	distal	-4	no	24.069	15.776	EPSD	COSMIC	22.404	Loss
CK1_CK1_CK1-D_CSNK1E_ST	P35222	CTNNB1	P49674	CSNK1E	S250	G245A	245	Missense	distal	-5	no	24.069	23.791	EPSD	COSMIC;GDSC	22.404	Down-regulation
CK1_CK1_CK1-D_CSNK1E_ST	P35222	CTNNB1	P49674	CSNK1E	S250	G245D	245	Missense	distal	-5	no	24.069	23.527	EPSD	COSMIC	22.404	Down-regulation
CK1_CK1_CK1-D_CSNK1E_ST	P35222	CTNNB1	P49674	CSNK1E	T556	E562K	562	Missense	distal	6	no	23.473	25.163	EPSD	COSMIC	22.404	Up-regulation
CK1_CK1_CK1-D_CSNK1E_ST	P35222	CTNNB1	P49674	CSNK1E	T556	T551K	551	Missense	distal	-5	no	23.473	23.218	EPSD	COSMIC	22.404	Down-regulation
CK1_CK1_CK1-D_CSNK1E_ST	P35222	CTNNB1	P49674	CSNK1E	T556	R549C	549	Missense	distal	-7	no	23.473	23.476	EPSD	COSMIC	22.404	Up-regulation
CK1_CK1_CK1-D_CSNK1E_ST	P35222	CTNNB1	P49674	CSNK1E	T556	E562G	562	Missense	distal	6	no	23.473	24.775	EPSD	COSMIC	22.404	Up-regulation
CK1_CK1_CK1-D_CSNK1E_ST	P35222	CTNNB1	P49674	CSNK1E	T556	Q558H	558	Missense	proximal	2	no	23.473	22.961	EPSD	COSMIC	22.404	Down-regulation
CK1_CK1_CK1-D_CSNK1E_ST	P35222	CTNNB1	P49674	CSNK1E	T556	G555A	555	Missense	proximal	-1	no	23.473	28.328	EPSD	COSMIC	22.404	Up-regulation
CK1_CK1_CK1-D_CSNK1E_ST	P35222	CTNNB1	P49674	CSNK1E	T556	R550H	550	Missense	distal	-6	no	23.473	24.156	EPSD	COSMIC	22.404	Up-regulation
CK1_CK1_CK1-D_CSNK1E_ST	P35222	CTNNB1	P49674	CSNK1E	T556	R550L	550	Missense	distal	-6	no	23.473	23.517	EPSD	COSMIC	22.404	Up-regulation
CK1_CK1_CK1-D_CSNK1E_ST	P35222	CTNNB1	P49674	CSNK1E	T556	G563R	563	Missense	distal	7	no	23.473	23.570	EPSD	COSMIC	22.404	Up-regulation
CK1_CK1_CK1-D_CSNK1E_ST	P35222	CTNNB1	P49674	CSNK1E	T556	S552F	552	Missense	distal	-4	no	23.473	18.351	EPSD	COSMIC	22.404	Loss
CK1_CK1_CK1-D_CSNK1E_ST	P35222	CTNNB1	P49674	CSNK1E	T556	G554D	554	Missense	proximal	-2	no	23.473	21.641	EPSD	COSMIC	22.404	Loss
CK1_CK1_CK1-D_CSNK1E_ST	P35222	CTNNB1	P49674	CSNK1E	T556	R550Q	550	Missense	distal	-6	no	23.473	23.929	EPSD	COSMIC	22.404	Up-regulation
CK1_CK1_CK1-D_CSNK1E_ST	P35222	CTNNB1	P49674	CSNK1E	T556	T551I	551	Missense	distal	-5	no	23.473	23.782	EPSD	COSMIC	22.404	Up-regulation
CK1_CK1_CK1-D_CSNK1E_ST	Q13541	EIF4EBP1	P49674	CSNK1E	S83	S85F	85	Missense	proximal	2	no	27.070	25.882	EPSD	COSMIC	22.404	Down-regulation
CK1_CK1_CK1-D_CSNK1E_ST	Q13541	EIF4EBP1	P49674	CSNK1E	S86	S85F	85	Missense	proximal	-1	no	28.540	20.834	EPSD	COSMIC	22.404	Loss
CK1_CK1_CK1-D_CSNK1E_ST	Q13541	EIF4EBP1	P49674	CSNK1E	S96	N100H	100	Missense	distal	4	no	33.148	33.190	EPSD	COSMIC	22.404	Up-regulation
CK1_CK1_CK1-D_CSNK1E_ST	Q9BZL6	PRKD2	P49674	CSNK1E	S43	P41L	41	Missense	proximal	-2	no	22.985	17.700	EPSD	COSMIC;GDSC;CCLE	22.404	Loss
CK1_CK1_CK1-D_CSNK1E_ST	Q9BZL6	PRKD2	P49674	CSNK1E	S43	H48Y	48	Missense	distal	5	no	22.985	24.271	EPSD	COSMIC	22.404	Up-regulation
CK1_CK1_CK1-D_CSNK1E_ST	Q9BZL6	PRKD2	P49674	CSNK1E	S43	S46C	46	Missense	distal	3	no	22.985	13.893	EPSD	COSMIC	22.404	Loss
CK1_CK1_CK1-D_CSNK1E_ST	Q9BZL6	PRKD2	P49674	CSNK1E	S200	R195S	195	Missense	distal	-5	no	21.945	23.322	EPSD	COSMIC	22.404	Gain
CK1_CK1_CK1-D_CSNK1E_ST	Q9BZL6	PRKD2	P49674	CSNK1E	S225	R232H	232	Missense	distal	7	no	23.231	23.363	EPSD	COSMIC	22.404	Up-regulation
CK1_CK1_CK1-D_CSNK1E_ST	Q9BZL6	PRKD2	P49674	CSNK1E	S225	E220K	220	Missense	distal	-5	no	23.231	22.349	EPSD	COSMIC	22.404	Loss
CK1_CK1_CK1-D_CSNK1E_ST	Q9BZL6	PRKD2	P49674	CSNK1E	S225	R232L	232	Missense	distal	7	no	23.231	23.519	EPSD	COSMIC	22.404	Up-regulation
CK1_CK1_CK1-D_CSNK1E_ST	Q9BZL6	PRKD2	P49674	CSNK1E	S238	S237F	237	Missense	proximal	-1	no	29.192	21.486	EPSD	COSMIC	22.404	Loss
CK1_CK1_CK1-D_CSNK1E_ST	Q9BZL6	PRKD2	P49674	CSNK1E	S238	R232H	232	Missense	distal	-6	no	29.192	29.875	EPSD	COSMIC	22.404	Up-regulation
CK1_CK1_CK1-D_CSNK1E_ST	Q9BZL6	PRKD2	P49674	CSNK1E	S238	S239F	239	Missense	proximal	1	no	29.192	28.156	EPSD	COSMIC	22.404	Down-regulation
CK1_CK1_CK1-D_CSNK1E_ST	Q9BZL6	PRKD2	P49674	CSNK1E	S238	S241Y	241	Missense	distal	3	no	29.192	19.321	EPSD	COSMIC	22.404	Loss
CK1_CK1_CK1-D_CSNK1E_ST	Q9BZL6	PRKD2	P49674	CSNK1E	S238	R232L	232	Missense	distal	-6	no	29.192	29.236	EPSD	COSMIC	22.404	Up-regulation
CK1_CK1_CK1-D_CSNK1E_ST	Q9BZL6	PRKD2	P49674	CSNK1E	S239	S237F	237	Missense	proximal	-2	no	22.518	14.481	EPSD	COSMIC	22.404	Loss
CK1_CK1_CK1-D_CSNK1E_ST	Q9BZL6	PRKD2	P49674	CSNK1E	S239	R232H	232	Missense	distal	-7	no	22.518	22.517	EPSD	COSMIC	22.404	Down-regulation
CK1_CK1_CK1-D_CSNK1E_ST	Q9BZL6	PRKD2	P49674	CSNK1E	S239	S239F	239	Missense	central	0	yes	22.518	0.000	EPSD	COSMIC	22.404	Loss
CK1_CK1_CK1-D_CSNK1E_ST	Q9BZL6	PRKD2	P49674	CSNK1E	S239	S241Y	241	Missense	proximal	2	no	22.518	22.350	EPSD	COSMIC	22.404	Loss
CK1_CK1_CK1-D_CSNK1E_ST	Q9BZL6	PRKD2	P49674	CSNK1E	S239	R232L	232	Missense	distal	-7	no	22.518	22.519	EPSD	COSMIC	22.404	Up-regulation
CK1_CK1_CK1-D_CSNK1E_ST	Q9BZL6	PRKD2	P49674	CSNK1E	S241	S237F	237	Missense	distal	-4	no	32.129	27.007	EPSD	COSMIC	22.404	Down-regulation
CK1_CK1_CK1-D_CSNK1E_ST	Q9BZL6	PRKD2	P49674	CSNK1E	S241	S239F	239	Missense	proximal	-2	no	32.129	24.092	EPSD	COSMIC	22.404	Down-regulation
CK1_CK1_CK1-D_CSNK1E_ST	Q9BZL6	PRKD2	P49674	CSNK1E	S241	S241Y	241	Missense	central	0	yes	32.129	0.000	EPSD	COSMIC	22.404	Loss
CK1_CK1_CK1-D_CSNK1E_ST	Q9BZL6	PRKD2	P49674	CSNK1E	S244	R249S	249	Missense	distal	5	no	36.151	34.822	PhosphoSitePlus	COSMIC	22.404	Down-regulation
CK1_CK1_CK1-D_CSNK1E_ST	Q9BZL6	PRKD2	P49674	CSNK1E	S244	S237F	237	Missense	distal	-7	no	36.151	36.147	PhosphoSitePlus	COSMIC	22.404	Down-regulation
CK1_CK1_CK1-D_CSNK1E_ST	Q9BZL6	PRKD2	P49674	CSNK1E	S244	S239F	239	Missense	distal	-5	no	36.151	34.432	PhosphoSitePlus	COSMIC	22.404	Down-regulation
CK1_CK1_CK1-D_CSNK1E_ST	Q9BZL6	PRKD2	P49674	CSNK1E	S244	S241Y	241	Missense	distal	-3	no	36.151	31.921	PhosphoSitePlus	COSMIC	22.404	Down-regulation
CK1_CK1_CK1-D_CSNK1E_ST	Q9BZL6	PRKD2	P49674	CSNK1E	S245	R249S	249	Missense	distal	4	no	25.853	25.680	EPSD	COSMIC	22.404	Down-regulation
CK1_CK1_CK1-D_CSNK1E_ST	Q9BZL6	PRKD2	P49674	CSNK1E	S245	S239F	239	Missense	distal	-6	no	25.853	24.703	EPSD	COSMIC	22.404	Down-regulation
CK1_CK1_CK1-D_CSNK1E_ST	Q9BZL6	PRKD2	P49674	CSNK1E	S245	S241Y	241	Missense	distal	-4	no	25.853	20.712	EPSD	COSMIC	22.404	Loss
CK1_CK1_CK1-D_CSNK1E_ST	Q9BZL6	PRKD2	P49674	CSNK1E	S344	S347C	347	Missense	distal	3	no	22.484	13.391	EPSD	COSMIC	22.404	Loss
CK1_CK1_CK1-D_CSNK1E_ST	Q9BZL6	PRKD2	P49674	CSNK1E	S347	S347C	347	Missense	central	0	yes	22.533	0.000	EPSD	COSMIC	22.404	Loss
CK1_CK1_CK1-D_CSNK1E_ST	Q9BZL6	PRKD2	P49674	CSNK1E	S347	H354L	354	Missense	distal	7	no	22.533	22.688	EPSD	COSMIC	22.404	Up-regulation
CK1_CK1_CK1-D_CSNK1E_ST	Q9BZL6	PRKD2	P49674	CSNK1E	T714	F707L	707	Missense	distal	-7	no	27.170	27.169	EPSD	COSMIC	22.404	Down-regulation
CK1_CK1_CK1-D_CSNK1E_ST	Q9BZL6	PRKD2	P49674	CSNK1E	T714	P720H	720	Missense	distal	6	no	27.170	24.476	EPSD	COSMIC	22.404	Down-regulation
CK1_CK1_CK1-D_CSNK1E_ST	Q9BZL6	PRKD2	P49674	CSNK1E	T714	G713R	713	Missense	proximal	-1	no	27.170	22.087	EPSD	COSMIC	22.404	Loss
CK1_CK1_CK1-D_CSNK1E_ST	Q9BZL6	PRKD2	P49674	CSNK1E	T714	G713E	713	Missense	proximal	-1	no	27.170	28.822	EPSD	COSMIC	22.404	Up-regulation
CK1_CK1_CK1-D_CSNK1E_ST	O60716	CTNND1	P49674	CSNK1E	S8	A14V	14	Missense	distal	6	no	30.444	28.942	EPSD	COSMIC	22.404	Down-regulation
CK1_CK1_CK1-D_CSNK1E_ST	O60716	CTNND1	P49674	CSNK1E	S8	S8L	8	Missense	central	0	yes	30.444	0.000	EPSD	COSMIC	22.404	Loss
CK1_CK1_CK1-D_CSNK1E_ST	O60716	CTNND1	P49674	CSNK1E	T9	A14V	14	Missense	distal	5	no	23.159	24.077	EPSD	COSMIC	22.404	Up-regulation
CK1_CK1_CK1-D_CSNK1E_ST	O60716	CTNND1	P49674	CSNK1E	T9	S8L	8	Missense	proximal	-1	no	23.159	14.852	EPSD	COSMIC	22.404	Loss
CK1_CK1_CK1-D_CSNK1E_ST	O60716	CTNND1	P49674	CSNK1E	S47	V46A	46	Missense	proximal	-1	no	17.610	25.278	EPSD	COSMIC	22.404	Gain
CK1_CK1_CK1-D_CSNK1E_ST	O60716	CTNND1	P49674	CSNK1E	T111	P105R	105	Missense	distal	-6	no	24.169	23.500	EPSD	COSMIC	22.404	Down-regulation
CK1_CK1_CK1-D_CSNK1E_ST	O60716	CTNND1	P49674	CSNK1E	T111	I108N	108	Missense	distal	-3	no	24.169	22.424	EPSD	COSMIC	22.404	Down-regulation
CK1_CK1_CK1-D_CSNK1E_ST	O60716	CTNND1	P49674	CSNK1E	T128	T134I	134	Missense	distal	6	no	21.448	22.433	EPSD	COSMIC	22.404	Gain
CK1_CK1_CK1-D_CSNK1E_ST	O60716	CTNND1	P49674	CSNK1E	S168	S168G	168	Missense	central	0	yes	25.621	0.000	EPSD	COSMIC	22.404	Loss
CK1_CK1_CK1-D_CSNK1E_ST	O60716	CTNND1	P49674	CSNK1E	S168	A167V	167	Missense	proximal	-1	no	25.621	17.953	EPSD	COSMIC	22.404	Loss
CK1_CK1_CK1-D_CSNK1E_ST	O60716	CTNND1	P49674	CSNK1E	S230	T235I	235	Missense	distal	5	no	22.077	23.116	EPSD	COSMIC	22.404	Gain
CK1_CK1_CK1-D_CSNK1E_ST	O60716	CTNND1	P49674	CSNK1E	S268	H273Y	273	Missense	distal	5	no	44.781	46.067	PhosphoSitePlus	COSMIC	22.404	Up-regulation
CK1_CK1_CK1-D_CSNK1E_ST	O60716	CTNND1	P49674	CSNK1E	S268	V270M	270	Missense	proximal	2	no	44.781	45.001	PhosphoSitePlus	COSMIC	22.404	Up-regulation
CK1_CK1_CK1-D_CSNK1E_ST	O60716	CTNND1	P49674	CSNK1E	S268	S269G	269	Missense	proximal	1	no	44.781	43.802	PhosphoSitePlus	COSMIC	22.404	Down-regulation
CK1_CK1_CK1-D_CSNK1E_ST	O60716	CTNND1	P49674	CSNK1E	S268	S268N	268	Missense	central	0	yes	44.781	0.000	PhosphoSitePlus	COSMIC	22.404	Loss
CK1_CK1_CK1-D_CSNK1E_ST	O60716	CTNND1	P49674	CSNK1E	S861	H863D	863	Missense	proximal	2	no	23.023	22.584	EPSD	COSMIC	22.404	Down-regulation
CK1_CK1_CK1-D_CSNK1E_ST	O60716	CTNND1	P49674	CSNK1E	S861	N855S	855	Missense	distal	-6	no	23.023	23.456	EPSD	COSMIC	22.404	Up-regulation
CK1_CK1_CK1-D_CSNK1E_ST	O60716	CTNND1	P49674	CSNK1E	S943	M936L	936	Missense	distal	-7	no	23.434	23.433	EPSD	COSMIC;GDSC	22.404	Down-regulation
CK1_CK1_CK1-D_CSNK1E_ST	O60353	FZD6	P49674	CSNK1E	S624	S620T	620	Missense	distal	-4	no	31.668	30.027	EPSD	COSMIC	22.404	Down-regulation
CK1_CK1_CK1-D_CSNK1E_ST	O60353	FZD6	P49674	CSNK1E	S624	S620L	620	Missense	distal	-4	no	31.668	23.375	EPSD	COSMIC	22.404	Down-regulation
CK1_CK1_CK1-D_CSNK1E_ST	O60353	FZD6	P49674	CSNK1E	S624	E617Q	617	Missense	distal	-7	no	31.668	31.669	EPSD	COSMIC	22.404	Up-regulation
CK1_CK1_CK1-D_CSNK1E_ST	O60353	FZD6	P49674	CSNK1E	S645	R647Q	647	Missense	proximal	2	no	33.678	35.510	EPSD	COSMIC;CCLE	22.404	Up-regulation
CK1_CK1_CK1-D_CSNK1E_ST	O60353	FZD6	P49674	CSNK1E	S648	R647Q	647	Missense	proximal	-1	no	22.685	25.532	PhosphoSitePlus	COSMIC;CCLE	22.404	Up-regulation
CK1_CK1_CK1-D_CSNK1E_ST	O60353	FZD6	P49674	CSNK1E	S674	P677S	677	Missense	distal	3	no	28.754	29.736	EPSD	COSMIC	22.404	Up-regulation
CK1_CK1_CK1-D_CSNK1E_ST	O60353	FZD6	P49674	CSNK1E	S675	P677S	677	Missense	proximal	2	no	22.598	24.173	EPSD	COSMIC	22.404	Up-regulation
CK1_CK1_CK1-D_CSNK1E_ST	O60353	FZD6	P49674	CSNK1E	S678	P677S	677	Missense	proximal	-1	no	22.221	23.125	EPSD	COSMIC	22.404	Gain
CAMK_CAMK1_CAMK1_ST	Q9UQL6	HDAC5	Q14012	CAMK1	S16	G12R	12	Missense	distal	-4	no	27.784	33.814	EPSD	COSMIC	32.882	Gain
CAMK_CAMK1_CAMK1_ST	Q9UQL6	HDAC5	Q14012	CAMK1	S259	R255C	255	Missense	distal	-4	no	50.374	42.969	EPSD;PhosphoSitePlus	COSMIC	32.882	Down-regulation
CAMK_CAMK1_CAMK1_ST	Q9UQL6	HDAC5	Q14012	CAMK1	S259	R266C	266	Missense	distal	7	no	50.374	51.458	EPSD;PhosphoSitePlus	COSMIC	32.882	Up-regulation
CAMK_CAMK1_CAMK1_ST	Q9UQL6	HDAC5	Q14012	CAMK1	S259	R266H	266	Missense	distal	7	no	50.374	50.859	EPSD;PhosphoSitePlus	COSMIC	32.882	Up-regulation
CAMK_CAMK1_CAMK1_ST	Q9UQL6	HDAC5	Q14012	CAMK1	S458	R455Q	455	Missense	distal	-3	no	39.914	30.847	EPSD	COSMIC	32.882	Loss
CAMK_CAMK1_CAMK1_ST	Q9UQL6	HDAC5	Q14012	CAMK1	S458	R455W	455	Missense	distal	-3	no	39.914	23.852	EPSD	COSMIC	32.882	Loss
CAMK_CAMK1_CAMK1_ST	Q9UQL6	HDAC5	Q14012	CAMK1	S458	L460I	460	Missense	proximal	2	no	39.914	40.530	EPSD	COSMIC	32.882	Up-regulation
CAMK_CAMK1_CAMK1_ST	Q9UQL6	HDAC5	Q14012	CAMK1	S498	R491W	491	Missense	distal	-7	no	50.850	49.761	PhosphoSitePlus;EPSD	COSMIC	32.882	Down-regulation
CAMK_CAMK1_CAMK1_ST	Q9UQL6	HDAC5	Q14012	CAMK1	T546	E550D	550	Missense	distal	4	no	36.489	37.475	EPSD	COSMIC	32.882	Up-regulation
CAMK_CAMK1_CAMK1_ST	Q9UQL6	HDAC5	Q14012	CAMK1	T546	E553K	553	Missense	distal	7	no	36.489	37.415	EPSD	COSMIC	32.882	Up-regulation
CAMK_CAMK1_CAMK1_ST	Q9UQL6	HDAC5	Q14012	CAMK1	S661	R658L	658	Missense	distal	-3	no	41.904	27.457	EPSD	COSMIC	32.882	Loss
CAMK_CAMK1_CAMK1_ST	Q9UQL6	HDAC5	Q14012	CAMK1	S661	R658H	658	Missense	distal	-3	no	41.904	34.677	EPSD	COSMIC	32.882	Down-regulation
CAMK_CAMK1_CAMK1_ST	Q9UQL6	HDAC5	Q14012	CAMK1	S661	T659S	659	Missense	proximal	-2	no	41.904	38.210	EPSD	COSMIC	32.882	Down-regulation
CAMK_CAMK1_CAMK1_ST	Q9UQL6	HDAC5	Q14012	CAMK1	S713	R717H	717	Missense	distal	4	no	31.893	33.216	EPSD	COSMIC	32.882	Gain
CAMK_CAMK1_CAMK1_ST	Q9UQL6	HDAC5	Q14012	CAMK1	S1108	E1106K	1106	Missense	proximal	-2	no	29.692	37.870	EPSD	COSMIC	32.882	Gain
CAMK_CAMK1_CAMK1_ST	P46527	CDKN1B	Q14012	CAMK1	S106	Q107R	107	Missense	proximal	1	no	34.909	37.468	EPSD	COSMIC	32.882	Up-regulation
CAMK_CAMK1_CAMK1_ST	P46527	CDKN1B	Q14012	CAMK1	S106	D108N	108	Missense	proximal	2	no	34.909	34.071	EPSD	COSMIC	32.882	Down-regulation
CAMK_CAMK1_CAMK1_ST	P46527	CDKN1B	Q14012	CAMK1	T157	A156V	156	Missense	proximal	-1	no	48.065	48.033	PhosphoSitePlus;EPSD	COSMIC	32.882	Down-regulation
CAMK_CAMK1_CAMK1_ST	P46527	CDKN1B	Q14012	CAMK1	T157	D158Y	158	Missense	proximal	1	no	48.065	48.117	PhosphoSitePlus;EPSD	COSMIC	32.882	Up-regulation
CAMK_CAMK1_CAMK1_ST	P46527	CDKN1B	Q14012	CAMK1	T157	T157N	157	Missense	central	0	yes	48.065	0.000	PhosphoSitePlus;EPSD	COSMIC	32.882	Loss
CAMK_CAMK1_CAMK1_ST	P46527	CDKN1B	Q14012	CAMK1	T157	D159Y	159	Missense	proximal	2	no	48.065	47.705	PhosphoSitePlus;EPSD	COSMIC	32.882	Down-regulation
CAMK_CAMK1_CAMK1_ST	P46527	CDKN1B	Q14012	CAMK1	T157	S161F	161	Missense	distal	4	no	48.065	48.846	PhosphoSitePlus;EPSD	COSMIC	32.882	Up-regulation
CAMK_CAMK1_CAMK1_ST	P46527	CDKN1B	Q14012	CAMK1	T170	R169K	169	Missense	proximal	-1	no	43.298	43.308	EPSD	COSMIC	32.882	Up-regulation
CAMK_CAMK1_CAMK1_ST	P46527	CDKN1B	Q14012	CAMK1	T170	N168K	168	Missense	proximal	-2	no	43.298	46.005	EPSD	COSMIC	32.882	Up-regulation
CAMK_CAMK1_CAMK1_ST	P46527	CDKN1B	Q14012	CAMK1	T198	R194K	194	Missense	distal	-4	no	47.865	45.522	EPSD;PhosphoSitePlus	COSMIC	32.882	Down-regulation
CAMK_CAMK1_CAMK1_ST	Q9NP62	GCM1	Q14012	CAMK1	S47	Y40F	40	Missense	distal	-7	no	46.907	45.858	PhosphoSitePlus	COSMIC	32.882	Down-regulation
CAMK_CAMK1_CAMK1_ST	Q9NP62	GCM1	Q14012	CAMK1	S47	S47L	47	Missense	central	0	yes	46.907	0.000	PhosphoSitePlus	COSMIC	32.882	Loss
CAMK_CAMK1_CAMK1_ST	Q9NP62	GCM1	Q14012	CAMK1	S269	S276C	276	Missense	distal	7	no	39.497	40.644	EPSD	COSMIC	32.882	Up-regulation
CAMK_CAMK1_CAMK1_ST	Q9NP62	GCM1	Q14012	CAMK1	S269	R266H	266	Missense	distal	-3	no	39.497	32.269	EPSD	COSMIC;GDSC;CCLE	32.882	Loss
CAMK_CAMK1_CAMK1_ST	Q9NP62	GCM1	Q14012	CAMK1	S269	Y263N	263	Missense	distal	-6	no	39.497	39.121	EPSD	COSMIC	32.882	Down-regulation
CAMK_CAMK1_CAMK1_ST	O43432	EIF4G3	Q14012	CAMK1	T168	S164I	164	Missense	distal	-4	no	36.626	35.888	EPSD	COSMIC	32.882	Down-regulation
CAMK_CAMK1_CAMK1_ST	O43432	EIF4G3	Q14012	CAMK1	T168	T175A	175	Missense	distal	7	no	36.626	38.138	EPSD	COSMIC	32.882	Up-regulation
CAMK_CAMK1_CAMK1_ST	O43432	EIF4G3	Q14012	CAMK1	S176	T179A	179	Missense	distal	3	no	37.890	37.895	EPSD	COSMIC	32.882	Up-regulation
CAMK_CAMK1_CAMK1_ST	O43432	EIF4G3	Q14012	CAMK1	S176	T175A	175	Missense	proximal	-1	no	37.890	37.888	EPSD	COSMIC	32.882	Down-regulation
CAMK_CAMK1_CAMK1_ST	O43432	EIF4G3	Q14012	CAMK1	T322	C319R	319	Missense	distal	-3	no	1.299	41.982	EPSD	COSMIC	32.882	Gain
CAMK_CAMK1_CAMK1_ST	O43432	EIF4G3	Q14012	CAMK1	S367	E364K	364	Missense	distal	-3	no	30.877	35.060	EPSD	COSMIC;GDSC;CCLE	32.882	Gain
CAMK_CAMK1_CAMK1_ST	O43432	EIF4G3	Q14012	CAMK1	S371	E370K	370	Missense	proximal	-1	no	37.311	37.377	EPSD	COSMIC	32.882	Up-regulation
CAMK_CAMK1_CAMK1_ST	O43432	EIF4G3	Q14012	CAMK1	S371	E364K	364	Missense	distal	-7	no	37.311	36.979	EPSD	COSMIC;GDSC;CCLE	32.882	Down-regulation
CAMK_CAMK1_CAMK1_ST	O43432	EIF4G3	Q14012	CAMK1	S371	T369M	369	Missense	proximal	-2	no	37.311	33.758	EPSD	COSMIC	32.882	Down-regulation
CAMK_CAMK1_CAMK1_ST	O43432	EIF4G3	Q14012	CAMK1	S371	S371R	371	Missense	central	0	yes	37.311	0.000	EPSD	COSMIC	32.882	Loss
CAMK_CAMK1_CAMK1_ST	O43432	EIF4G3	Q14012	CAMK1	S495	P496L	496	Missense	proximal	1	no	31.377	33.941	EPSD	COSMIC	32.882	Gain
CAMK_CAMK1_CAMK1_ST	O43432	EIF4G3	Q14012	CAMK1	S495	P496A	496	Missense	proximal	1	no	31.377	35.777	EPSD	COSMIC	32.882	Gain
CAMK_CAMK1_CAMK1_ST	O43432	EIF4G3	Q14012	CAMK1	T518	R515Q	515	Missense	distal	-3	no	43.249	34.183	EPSD	COSMIC	32.882	Down-regulation
CAMK_CAMK1_CAMK1_ST	O43432	EIF4G3	Q14012	CAMK1	T518	R517Q	517	Missense	proximal	-1	no	43.249	43.209	EPSD	COSMIC	32.882	Down-regulation
CAMK_CAMK1_CAMK1_ST	O43432	EIF4G3	Q14012	CAMK1	T518	P512S	512	Missense	distal	-6	no	43.249	43.966	EPSD	COSMIC	32.882	Up-regulation
CAMK_CAMK1_CAMK1_ST	O43432	EIF4G3	Q14012	CAMK1	S543	M548L	548	Missense	distal	5	no	36.795	36.645	EPSD	COSMIC;GDSC	32.882	Down-regulation
CAMK_CAMK1_CAMK1_ST	O43432	EIF4G3	Q14012	CAMK1	S543	L541I	541	Missense	proximal	-2	no	36.795	31.681	EPSD	COSMIC	32.882	Loss
CAMK_CAMK1_CAMK1_ST	O43432	EIF4G3	Q14012	CAMK1	S543	S549R	549	Missense	distal	6	no	36.795	36.968	EPSD	COSMIC	32.882	Up-regulation
CAMK_CAMK1_CAMK1_ST	O43432	EIF4G3	Q14012	CAMK1	S719	L726R	726	Missense	distal	7	no	33.860	33.077	EPSD	COSMIC	32.882	Down-regulation
CAMK_CAMK1_CAMK1_ST	O43432	EIF4G3	Q14012	CAMK1	S719	V720A	720	Missense	proximal	1	no	33.860	36.164	EPSD	COSMIC	32.882	Up-regulation
CAMK_CAMK1_CAMK1_ST	O43432	EIF4G3	Q14012	CAMK1	S719	L726M	726	Missense	distal	7	no	33.860	34.406	EPSD	COSMIC	32.882	Up-regulation
CAMK_CAMK1_CAMK1_ST	O43432	EIF4G3	Q14012	CAMK1	S719	I716M	716	Missense	distal	-3	no	33.860	17.602	EPSD	COSMIC	32.882	Loss
CAMK_CAMK1_CAMK1_ST	O43432	EIF4G3	Q14012	CAMK1	S741	K734N	734	Missense	distal	-7	no	39.711	39.649	EPSD	COSMIC	32.882	Down-regulation
CAMK_CAMK1_CAMK1_ST	O43432	EIF4G3	Q14012	CAMK1	S741	S741G	741	Missense	central	0	yes	39.711	0.000	EPSD	COSMIC	32.882	Loss
CAMK_CAMK1_CAMK1_ST	O43432	EIF4G3	Q14012	CAMK1	S741	Q742K	742	Missense	proximal	1	no	39.711	38.859	EPSD	COSMIC	32.882	Down-regulation
CAMK_CAMK1_CAMK1_ST	O43432	EIF4G3	Q14012	CAMK1	S741	S741R	741	Missense	central	0	yes	39.711	0.000	EPSD	COSMIC;GDSC	32.882	Loss
CAMK_CAMK1_CAMK1_ST	O43432	EIF4G3	Q14012	CAMK1	S741	D744N	744	Missense	distal	3	no	39.711	39.717	EPSD	COSMIC	32.882	Up-regulation
CAMK_CAMK1_CAMK1_ST	O43432	EIF4G3	Q14012	CAMK1	S741	P746L	746	Missense	distal	5	no	39.711	41.630	EPSD	COSMIC	32.882	Up-regulation
CAMK_CAMK1_CAMK1_ST	O43432	EIF4G3	Q14012	CAMK1	S741	E747K	747	Missense	distal	6	no	39.711	39.085	EPSD	COSMIC	32.882	Down-regulation
CAMK_CAMK1_CAMK1_ST	O43432	EIF4G3	Q14012	CAMK1	S778	G779E	779	Missense	proximal	1	no	29.418	36.429	EPSD	COSMIC	32.882	Gain
CAMK_CAMK1_CAMK1_ST	O43432	EIF4G3	Q14012	CAMK1	S866	A864V	864	Missense	proximal	-2	no	38.565	37.927	EPSD	COSMIC	32.882	Down-regulation
CAMK_CAMK1_CAMK1_ST	O43432	EIF4G3	Q14012	CAMK1	S866	E861K	861	Missense	distal	-5	no	38.565	41.285	EPSD	COSMIC	32.882	Up-regulation
CAMK_CAMK1_CAMK1_ST	O43432	EIF4G3	Q14012	CAMK1	S866	A864T	864	Missense	proximal	-2	no	38.565	41.931	EPSD	COSMIC	32.882	Up-regulation
CAMK_CAMK1_CAMK1_ST	O43432	EIF4G3	Q14012	CAMK1	S866	P868S	868	Missense	proximal	2	no	38.565	39.705	EPSD	COSMIC	32.882	Up-regulation
CAMK_CAMK1_CAMK1_ST	O43432	EIF4G3	Q14012	CAMK1	S866	P868L	868	Missense	proximal	2	no	38.565	39.029	EPSD	COSMIC	32.882	Up-regulation
CAMK_CAMK1_CAMK1_ST	O43432	EIF4G3	Q14012	CAMK1	S889	R887W	887	Missense	proximal	-2	no	41.360	32.450	EPSD	COSMIC	32.882	Loss
CAMK_CAMK1_CAMK1_ST	O43432	EIF4G3	Q14012	CAMK1	S889	A885V	885	Missense	distal	-4	no	41.360	39.735	EPSD	COSMIC;GDSC;CCLE	32.882	Down-regulation
CAMK_CAMK1_CAMK1_ST	O43432	EIF4G3	Q14012	CAMK1	S889	R886Q	886	Missense	distal	-3	no	41.360	32.293	EPSD	COSMIC;GDSC	32.882	Loss
CAMK_CAMK1_CAMK1_ST	O43432	EIF4G3	Q14012	CAMK1	S1074	Q1071K	1071	Missense	distal	-3	no	30.798	33.646	EPSD	COSMIC	32.882	Gain
CAMK_CAMK1_CAMK1_ST	O43432	EIF4G3	Q14012	CAMK1	S1093	R1092W	1092	Missense	proximal	-1	no	37.234	37.158	EPSD	COSMIC	32.882	Down-regulation
CAMK_CAMK1_CAMK1_ST	O43432	EIF4G3	Q14012	CAMK1	S1093	R1100K	1100	Missense	distal	7	no	37.234	37.478	EPSD	COSMIC	32.882	Up-regulation
CAMK_CAMK1_CAMK1_ST	O43432	EIF4G3	Q14012	CAMK1	T1127	R1129H	1129	Missense	proximal	2	no	39.298	39.770	EPSD	COSMIC	32.882	Up-regulation
CAMK_CAMK1_CAMK1_ST	O43432	EIF4G3	Q14012	CAMK1	T1127	R1134S	1134	Missense	distal	7	no	39.298	39.235	EPSD	COSMIC	32.882	Down-regulation
CAMK_CAMK1_CAMK1_ST	O43432	EIF4G3	Q14012	CAMK1	T1127	T1125P	1125	Missense	proximal	-2	no	39.298	31.041	EPSD	COSMIC	32.882	Loss
CAMK_CAMK1_CAMK1_ST	O43432	EIF4G3	Q14012	CAMK1	S1131	T1125P	1125	Missense	distal	-6	no	32.827	33.447	EPSD	COSMIC	32.882	Gain
CAMK_CAMK1_CAMK1_ST	O43432	EIF4G3	Q14012	CAMK1	T1145	P1142L	1142	Missense	distal	-3	no	18.683	34.028	EPSD	COSMIC	32.882	Gain
CAMK_CAMK1_CAMK1_ST	O43432	EIF4G3	Q14012	CAMK1	T1150	A1144T	1144	Missense	distal	-6	no	37.406	37.907	EPSD	COSMIC	32.882	Up-regulation
CAMK_CAMK1_CAMK1_ST	O43432	EIF4G3	Q14012	CAMK1	T1150	R1153W	1153	Missense	distal	3	no	37.406	37.426	EPSD	COSMIC	32.882	Up-regulation
CAMK_CAMK1_CAMK1_ST	O43432	EIF4G3	Q14012	CAMK1	T1150	P1148L	1148	Missense	proximal	-2	no	37.406	43.647	EPSD	COSMIC	32.882	Up-regulation
CAMK_CAMK1_CAMK1_ST	O43432	EIF4G3	Q14012	CAMK1	T1150	R1153S	1153	Missense	distal	3	no	37.406	37.417	EPSD	COSMIC	32.882	Up-regulation
CAMK_CAMK1_CAMK1_ST	O43432	EIF4G3	Q14012	CAMK1	T1150	P1148S	1148	Missense	proximal	-2	no	37.406	41.969	EPSD	COSMIC	32.882	Up-regulation
CAMK_CAMK1_CAMK1_ST	O43432	EIF4G3	Q14012	CAMK1	T1150	R1147W	1147	Missense	distal	-3	no	37.406	21.344	EPSD	COSMIC	32.882	Loss
CAMK_CAMK1_CAMK1_ST	O43432	EIF4G3	Q14012	CAMK1	T1150	S1156Y	1156	Missense	distal	6	no	37.406	37.262	EPSD	COSMIC	32.882	Down-regulation
CAMK_CAMK1_CAMK1_ST	O43432	EIF4G3	Q14012	CAMK1	S1156	R1153W	1153	Missense	distal	-3	no	48.289	32.227	PhosphoSitePlus	COSMIC	32.882	Loss
CAMK_CAMK1_CAMK1_ST	O43432	EIF4G3	Q14012	CAMK1	S1156	D1162Y	1162	Missense	distal	6	no	48.289	48.571	PhosphoSitePlus	COSMIC	32.882	Up-regulation
CAMK_CAMK1_CAMK1_ST	O43432	EIF4G3	Q14012	CAMK1	S1156	R1153S	1153	Missense	distal	-3	no	48.289	27.383	PhosphoSitePlus	COSMIC	32.882	Loss
CAMK_CAMK1_CAMK1_ST	O43432	EIF4G3	Q14012	CAMK1	S1156	D1162E	1162	Missense	distal	6	no	48.289	48.940	PhosphoSitePlus	COSMIC	32.882	Up-regulation
CAMK_CAMK1_CAMK1_ST	O43432	EIF4G3	Q14012	CAMK1	S1156	S1156Y	1156	Missense	central	0	yes	48.289	0.000	PhosphoSitePlus	COSMIC	32.882	Loss
CAMK_CAMK1_CAMK1_ST	O43432	EIF4G3	Q14012	CAMK1	S1165	D1162E	1162	Missense	distal	-3	no	3.803	36.162	EPSD	COSMIC	32.882	Gain
CAMK_CAMK1_CAMK1_ST	O43432	EIF4G3	Q14012	CAMK1	S1190	D1185Y	1185	Missense	distal	-5	no	28.843	35.216	EPSD	COSMIC	32.882	Gain
CAMK_CAMK1_CAMK1_ST	O43432	EIF4G3	Q14012	CAMK1	T1191	D1185Y	1185	Missense	distal	-6	no	40.781	40.989	EPSD	COSMIC	32.882	Up-regulation
CAMK_CAMK1_CAMK1_ST	O43432	EIF4G3	Q14012	CAMK1	T1191	K1197I	1197	Missense	distal	6	no	40.781	40.830	EPSD	COSMIC	32.882	Up-regulation
CAMK_CAMK1_CAMK1_ST	O43432	EIF4G3	Q14012	CAMK1	T1191	R1195Q	1195	Missense	distal	4	no	40.781	41.369	EPSD	COSMIC	32.882	Up-regulation
CAMK_CAMK1_CAMK1_ST	O43432	EIF4G3	Q14012	CAMK1	T1191	D1185E	1185	Missense	distal	-6	no	40.781	39.911	EPSD	COSMIC	32.882	Down-regulation
CAMK_CAMK1_CAMK1_ST	O43432	EIF4G3	Q14012	CAMK1	T1191	E1187G	1187	Missense	distal	-4	no	40.781	39.451	EPSD	COSMIC	32.882	Down-regulation
CAMK_CAMK1_CAMK1_ST	O43432	EIF4G3	Q14012	CAMK1	T1191	E1192A	1192	Missense	proximal	1	no	40.781	37.728	EPSD	COSMIC	32.882	Down-regulation
CAMK_CAMK1_CAMK1_ST	O43432	EIF4G3	Q14012	CAMK1	T1198	K1203I	1203	Missense	distal	5	no	37.923	34.787	EPSD	COSMIC	32.882	Down-regulation
CAMK_CAMK1_CAMK1_ST	O43432	EIF4G3	Q14012	CAMK1	T1198	E1200D	1200	Missense	proximal	2	no	37.923	38.052	EPSD	COSMIC	32.882	Up-regulation
CAMK_CAMK1_CAMK1_ST	O43432	EIF4G3	Q14012	CAMK1	T1198	K1197I	1197	Missense	proximal	-1	no	37.923	37.855	EPSD	COSMIC	32.882	Down-regulation
CAMK_CAMK1_CAMK1_ST	O43432	EIF4G3	Q14012	CAMK1	T1198	E1200Q	1200	Missense	proximal	2	no	37.923	37.117	EPSD	COSMIC	32.882	Down-regulation
CAMK_CAMK1_CAMK1_ST	O43432	EIF4G3	Q14012	CAMK1	T1198	R1195Q	1195	Missense	distal	-3	no	37.923	28.856	EPSD	COSMIC	32.882	Loss
CAMK_CAMK1_CAMK1_ST	O43432	EIF4G3	Q14012	CAMK1	T1198	S1201L	1201	Missense	distal	3	no	37.923	37.925	EPSD	COSMIC	32.882	Up-regulation
CAMK_CAMK1_CAMK1_ST	O43432	EIF4G3	Q14012	CAMK1	T1198	E1205K	1205	Missense	distal	7	no	37.923	38.849	EPSD	COSMIC	32.882	Up-regulation
CAMK_CAMK1_CAMK1_ST	O43432	EIF4G3	Q14012	CAMK1	T1198	E1192A	1192	Missense	distal	-6	no	37.923	38.600	EPSD	COSMIC	32.882	Up-regulation
CAMK_CAMK1_CAMK1_ST	O43432	EIF4G3	Q14012	CAMK1	T1273	S1270R	1270	Missense	distal	-3	no	28.657	49.563	EPSD	COSMIC	32.882	Gain
CAMK_CAMK1_CAMK1_ST	O43432	EIF4G3	Q14012	CAMK1	T1481	D1478N	1478	Missense	distal	-3	no	10.211	33.322	EPSD	COSMIC	32.882	Gain
CAMK_CAMK1_CAMK1_ST	O43432	EIF4G3	Q14012	CAMK1	S1582	E1579K	1579	Missense	distal	-3	no	35.382	39.564	EPSD	COSMIC	32.882	Up-regulation
CAMK_CAMK1_CAMK1_ST	O43432	EIF4G3	Q14012	CAMK1	S1582	E1583K	1583	Missense	proximal	1	no	35.382	28.354	EPSD	COSMIC	32.882	Loss
CAMK_CAMK1_CAMK1_ST	O43432	EIF4G3	Q14012	CAMK1	S1582	E1577K	1577	Missense	distal	-5	no	35.382	38.101	EPSD	COSMIC	32.882	Up-regulation
CAMK_CAMK1_CAMK1_ST	P24844	MYL9	Q14012	CAMK1	T11	P15S	15	Missense	distal	4	no	34.276	33.904	EPSD	COSMIC	32.882	Down-regulation
CAMK_CAMK1_CAMK1_ST	P24844	MYL9	Q14012	CAMK1	T11	R14Q	14	Missense	distal	3	no	34.276	34.274	EPSD	COSMIC	32.882	Down-regulation
CAMK_CAMK1_CAMK1_ST	P24844	MYL9	Q14012	CAMK1	T19	N21T	21	Missense	proximal	2	no	41.883	41.807	EPSD	COSMIC	32.882	Down-regulation
CAMK_CAMK1_CAMK1_ST	P24844	MYL9	Q14012	CAMK1	T19	P15S	15	Missense	distal	-4	no	41.883	44.536	EPSD	COSMIC	32.882	Up-regulation
CAMK_CAMK1_CAMK1_ST	P24844	MYL9	Q14012	CAMK1	T19	R14Q	14	Missense	distal	-5	no	41.883	39.631	EPSD	COSMIC	32.882	Down-regulation
CAMK_CAMK1_CAMK1_ST	P24844	MYL9	Q14012	CAMK1	S20	N21T	21	Missense	proximal	1	no	50.791	52.771	PhosphoSitePlus	COSMIC	32.882	Up-regulation
CAMK_CAMK1_CAMK1_ST	P24844	MYL9	Q14012	CAMK1	S20	P15S	15	Missense	distal	-5	no	50.791	48.992	PhosphoSitePlus	COSMIC	32.882	Down-regulation
CAMK_CAMK1_CAMK1_ST	P24844	MYL9	Q14012	CAMK1	S20	R14Q	14	Missense	distal	-6	no	50.791	49.347	PhosphoSitePlus	COSMIC	32.882	Down-regulation
CAMK_CAMK1_CAMK1_ST	P24844	MYL9	Q14012	CAMK1	T128	R124W	124	Missense	distal	-4	no	39.643	33.671	EPSD	COSMIC	32.882	Down-regulation
CAMK_CAMK1_CAMK1_ST	P24844	MYL9	Q14012	CAMK1	T128	M130I	130	Missense	proximal	2	no	39.643	41.010	EPSD	COSMIC	32.882	Up-regulation
CAMK_CAMK1_CAMK1_ST	P24844	MYL9	Q14012	CAMK1	T128	D121N	121	Missense	distal	-7	no	39.643	39.606	EPSD	COSMIC	32.882	Down-regulation
CAMK_CAMK1_CAMK1_ST	P24844	MYL9	Q14012	CAMK1	T128	L123V	123	Missense	distal	-5	no	39.643	35.804	EPSD	COSMIC	32.882	Down-regulation
CAMK_CAMK1_CAMK1_ST	P24844	MYL9	Q14012	CAMK1	T128	R124Q	124	Missense	distal	-4	no	39.643	37.112	EPSD	COSMIC	32.882	Down-regulation
CAMK_CAMK1_CAMK1_ST	Q05469	LIPE	Q14012	CAMK1	S607	V603I	603	Missense	distal	-4	no	34.844	34.580	EPSD	COSMIC	32.882	Down-regulation
CAMK_CAMK1_CAMK1_ST	Q05469	LIPE	Q14012	CAMK1	T813	R818Q	818	Missense	distal	5	no	43.057	42.097	EPSD	COSMIC;GDSC	32.882	Down-regulation
CAMK_CAMK1_CAMK1_ST	Q05469	LIPE	Q14012	CAMK1	T813	L815P	815	Missense	proximal	2	no	43.057	42.593	EPSD	COSMIC	32.882	Down-regulation
CAMK_CAMK1_CAMK1_ST	Q05469	LIPE	Q14012	CAMK1	S951	G953C	953	Missense	proximal	2	no	34.694	33.309	EPSD	COSMIC	32.882	Down-regulation
CAMK_CAMK1_CAMK1_ST	Q05469	LIPE	Q14012	CAMK1	T1052	P1054R	1054	Missense	proximal	2	no	35.892	36.830	EPSD	COSMIC	32.882	Up-regulation
CAMK_CAMK1_CAMK1_ST	Q05469	LIPE	Q14012	CAMK1	T1052	R1048H	1048	Missense	distal	-4	no	35.892	32.001	EPSD	COSMIC	32.882	Loss
CAMK_CAMK1_CAMK1_ST	Q9UQM7	CAMK2A	Q14012	CAMK1	T10	R8C	8	Missense	proximal	-2	no	35.370	26.512	EPSD	COSMIC	32.882	Loss
CAMK_CAMK1_CAMK1_ST	Q9UQM7	CAMK2A	Q14012	CAMK1	T10	T10M	10	Missense	central	0	yes	35.370	0.000	EPSD	COSMIC	32.882	Loss
CAMK_CAMK1_CAMK1_ST	Q9UQM7	CAMK2A	Q14012	CAMK1	T10	T10A	10	Missense	central	0	yes	35.370	0.000	EPSD	COSMIC	32.882	Loss
CAMK_CAMK1_CAMK1_ST	Q9UQM7	CAMK2A	Q14012	CAMK1	T10	Y13H	13	Missense	distal	3	no	35.370	35.388	EPSD	COSMIC	32.882	Up-regulation
CAMK_CAMK1_CAMK1_ST	Q9UQM7	CAMK2A	Q14012	CAMK1	T276	S272L	272	Missense	distal	-4	no	40.965	39.889	EPSD	COSMIC	32.882	Down-regulation
CAMK_CAMK1_CAMK1_ST	Q9UQM7	CAMK2A	Q14012	CAMK1	S314	K317T	317	Missense	distal	3	no	40.259	40.239	EPSD	COSMIC	32.882	Down-regulation
CAMK_CAMK1_CAMK1_ST	Q9UQM7	CAMK2A	Q14012	CAMK1	S331	V327G	327	Missense	distal	-4	no	40.579	39.359	EPSD	COSMIC	32.882	Down-regulation
CAMK_CAMK1_CAMK1_ST	Q9Y570	PPME1	Q14012	CAMK1	S15	L13I	13	Missense	proximal	-2	no	50.189	45.075	PhosphoSitePlus	COSMIC	32.882	Down-regulation
CAMK_CAMK1_CAMK1_ST	Q9Y570	PPME1	Q14012	CAMK1	S15	P14L	14	Missense	proximal	-1	no	50.189	50.196	PhosphoSitePlus	COSMIC;CCLE	32.882	Up-regulation
CAMK_CAMK1_CAMK1_ST	Q9Y570	PPME1	Q14012	CAMK1	S15	L10I	10	Missense	distal	-5	no	50.189	49.102	PhosphoSitePlus	COSMIC	32.882	Down-regulation
CAMK_CAMK1_CAMK1_ST	P39019	RPS19	Q14012	CAMK1	S59	L66F	66	Missense	distal	7	no	49.508	50.329	PhosphoSitePlus	COSMIC	32.882	Up-regulation
CAMK_CAMK1_CAMK1_ST	Q9UKV0	HDAC9	Q14012	CAMK1	S12	D9H	9	Missense	distal	-3	no	-2.290	33.243	EPSD	COSMIC	32.882	Gain
CAMK_CAMK1_CAMK1_ST	Q9UKV0	HDAC9	Q14012	CAMK1	T141	V138E	138	Missense	distal	-3	no	36.021	35.161	EPSD	COSMIC	32.882	Down-regulation
CAMK_CAMK1_CAMK1_ST	Q9UKV0	HDAC9	Q14012	CAMK1	T141	V138M	138	Missense	distal	-3	no	36.021	18.988	EPSD	COSMIC	32.882	Loss
CAMK_CAMK1_CAMK1_ST	Q9UKV0	HDAC9	Q14012	CAMK1	T141	R136M	136	Missense	distal	-5	no	36.021	34.932	EPSD	COSMIC	32.882	Down-regulation
CAMK_CAMK1_CAMK1_ST	Q9UKV0	HDAC9	Q14012	CAMK1	T141	S140N	140	Missense	proximal	-1	no	36.021	36.007	EPSD	COSMIC	32.882	Down-regulation
CAMK_CAMK1_CAMK1_ST	Q9UKV0	HDAC9	Q14012	CAMK1	T141	E142D	142	Missense	proximal	1	no	36.021	32.473	EPSD	COSMIC	32.882	Loss
CAMK_CAMK1_CAMK1_ST	Q9UKV0	HDAC9	Q14012	CAMK1	T141	A137T	137	Missense	distal	-4	no	36.021	36.832	EPSD	COSMIC	32.882	Up-regulation
CAMK_CAMK1_CAMK1_ST	Q9UKV0	HDAC9	Q14012	CAMK1	T141	L147I	147	Missense	distal	6	no	36.021	36.070	EPSD	COSMIC	32.882	Up-regulation
CAMK_CAMK1_CAMK1_ST	Q9UKV0	HDAC9	Q14012	CAMK1	S220	R227W	227	Missense	distal	7	no	48.863	49.425	PhosphoSitePlus;EPSD	COSMIC	32.882	Up-regulation
CAMK_CAMK1_CAMK1_ST	Q9UKV0	HDAC9	Q14012	CAMK1	S220	R216Q	216	Missense	distal	-4	no	48.863	46.332	PhosphoSitePlus;EPSD	COSMIC	32.882	Down-regulation
CAMK_CAMK1_CAMK1_ST	Q9UKV0	HDAC9	Q14012	CAMK1	S220	P222L	222	Missense	proximal	2	no	48.863	49.327	PhosphoSitePlus;EPSD	COSMIC	32.882	Up-regulation
CAMK_CAMK1_CAMK1_ST	Q9UKV0	HDAC9	Q14012	CAMK1	S220	R227Q	227	Missense	distal	7	no	48.863	48.514	PhosphoSitePlus;EPSD	COSMIC	32.882	Down-regulation
CAMK_CAMK1_CAMK1_ST	Q9UKV0	HDAC9	Q14012	CAMK1	S220	L215F	215	Missense	distal	-5	no	48.863	47.204	PhosphoSitePlus;EPSD	COSMIC	32.882	Down-regulation
CAMK_CAMK1_CAMK1_ST	Q9UKV0	HDAC9	Q14012	CAMK1	S220	P222H	222	Missense	proximal	2	no	48.863	50.273	PhosphoSitePlus;EPSD	COSMIC	32.882	Up-regulation
CAMK_CAMK1_CAMK1_ST	Q9UKV0	HDAC9	Q14012	CAMK1	S220	S220F	220	Missense	central	0	yes	48.863	0.000	PhosphoSitePlus;EPSD	COSMIC	32.882	Loss
CAMK_CAMK1_CAMK1_ST	Q9UKV0	HDAC9	Q14012	CAMK1	S240	P241T	241	Missense	proximal	1	no	36.517	39.675	EPSD	COSMIC	32.882	Up-regulation
CAMK_CAMK1_CAMK1_ST	Q9UKV0	HDAC9	Q14012	CAMK1	S240	S240I	240	Missense	central	0	yes	36.517	0.000	EPSD	COSMIC	32.882	Loss
CAMK_CAMK1_CAMK1_ST	Q9UKV0	HDAC9	Q14012	CAMK1	S240	D247Y	247	Missense	distal	7	no	36.517	34.049	EPSD	COSMIC	32.882	Down-regulation
CAMK_CAMK1_CAMK1_ST	Q9UKV0	HDAC9	Q14012	CAMK1	S240	R238K	238	Missense	proximal	-2	no	36.517	36.246	EPSD	COSMIC	32.882	Down-regulation
CAMK_CAMK1_CAMK1_ST	Q9UKV0	HDAC9	Q14012	CAMK1	S240	S240R	240	Missense	central	0	yes	36.517	0.000	EPSD	COSMIC	32.882	Loss
CAMK_CAMK1_CAMK1_ST	Q9UKV0	HDAC9	Q14012	CAMK1	S240	R245Q	245	Missense	distal	5	no	36.517	35.557	EPSD	COSMIC	32.882	Down-regulation
CAMK_CAMK1_CAMK1_ST	Q9UKV0	HDAC9	Q14012	CAMK1	S451	L454W	454	Missense	distal	3	no	50.030	50.037	EPSD;PhosphoSitePlus	COSMIC	32.882	Up-regulation
CAMK_CAMK1_CAMK1_ST	Q9UKV0	HDAC9	Q14012	CAMK1	S451	P445L	445	Missense	distal	-6	no	50.030	49.337	EPSD;PhosphoSitePlus	COSMIC	32.882	Down-regulation
CAMK_CAMK1_CAMK1_ST	Q9UKV0	HDAC9	Q14012	CAMK1	S451	N447D	447	Missense	distal	-4	no	50.030	46.527	EPSD;PhosphoSitePlus	COSMIC	32.882	Down-regulation
CAMK_CAMK1_CAMK1_ST	Q9UKV0	HDAC9	Q14012	CAMK1	S451	P453H	453	Missense	proximal	2	no	50.030	51.440	EPSD;PhosphoSitePlus	COSMIC	32.882	Up-regulation
CAMK_CAMK1_CAMK1_ST	Q9UKV0	HDAC9	Q14012	CAMK1	S451	R448L	448	Missense	distal	-3	no	50.030	35.583	EPSD;PhosphoSitePlus	COSMIC	32.882	Down-regulation
CAMK_CAMK1_CAMK1_ST	Q9UKV0	HDAC9	Q14012	CAMK1	S451	R448Q	448	Missense	distal	-3	no	50.030	40.964	EPSD;PhosphoSitePlus	COSMIC	32.882	Down-regulation
CAMK_CAMK1_CAMK1_ST	Q9UKV0	HDAC9	Q14012	CAMK1	S451	P453L	453	Missense	proximal	2	no	50.030	50.494	EPSD;PhosphoSitePlus	COSMIC	32.882	Up-regulation
CAMK_CAMK1_CAMK1_ST	Q9UKV0	HDAC9	Q14012	CAMK1	S451	T458R	458	Missense	distal	7	no	50.030	50.695	EPSD;PhosphoSitePlus	COSMIC	32.882	Up-regulation
CAMK_CAMK1_CAMK1_ST	Q9UKV0	HDAC9	Q14012	CAMK1	S451	P445T	445	Missense	distal	-6	no	50.030	49.410	EPSD;PhosphoSitePlus	COSMIC	32.882	Down-regulation
CAMK_CAMK1_CAMK1_ST	Q9UKV0	HDAC9	Q14012	CAMK1	S451	P455H	455	Missense	distal	4	no	50.030	51.128	EPSD;PhosphoSitePlus	COSMIC	32.882	Up-regulation
CAMK_CAMK1_CAMK1_ST	Q9UKV0	HDAC9	Q14012	CAMK1	S451	R444G	444	Missense	distal	-7	no	50.030	48.467	EPSD;PhosphoSitePlus	COSMIC	32.882	Down-regulation
CAMK_CAMK1_CAMK1_ST	Q9UKV0	HDAC9	Q14012	CAMK1	S451	Q456H	456	Missense	distal	5	no	50.030	49.291	EPSD;PhosphoSitePlus	COSMIC	32.882	Down-regulation
CAMK_CAMK1_CAMK1_ST	Q9UKV0	HDAC9	Q14012	CAMK1	S607	L600S	600	Missense	distal	-7	no	38.783	38.717	EPSD	COSMIC	32.882	Down-regulation
CAMK_CAMK1_CAMK1_ST	Q9UKV0	HDAC9	Q14012	CAMK1	S607	A614V	614	Missense	distal	7	no	38.783	37.911	EPSD	COSMIC;CCLE	32.882	Down-regulation
CAMK_CAMK1_CAMK1_ST	Q9UKV0	HDAC9	Q14012	CAMK1	S607	V606L	606	Missense	proximal	-1	no	38.783	38.811	EPSD	COSMIC	32.882	Up-regulation
CAMK_CAMK1_CAMK1_ST	Q9UKV0	HDAC9	Q14012	CAMK1	S607	V606I	606	Missense	proximal	-1	no	38.783	38.786	EPSD	COSMIC;CCLE	32.882	Up-regulation
CAMK_CAMK1_CAMK1_ST	Q9UKV0	HDAC9	Q14012	CAMK1	S607	V606A	606	Missense	proximal	-1	no	38.783	38.814	EPSD	COSMIC	32.882	Up-regulation
CAMK_CAMK1_CAMK1_ST	Q9UKV0	HDAC9	Q14012	CAMK1	S611	A614V	614	Missense	distal	3	no	38.514	38.522	EPSD	COSMIC;CCLE	32.882	Up-regulation
CAMK_CAMK1_CAMK1_ST	Q9UKV0	HDAC9	Q14012	CAMK1	S611	V606L	606	Missense	distal	-5	no	38.514	42.353	EPSD	COSMIC	32.882	Up-regulation
CAMK_CAMK1_CAMK1_ST	Q9UKV0	HDAC9	Q14012	CAMK1	S611	V606I	606	Missense	distal	-5	no	38.514	41.266	EPSD	COSMIC;CCLE	32.882	Up-regulation
CAMK_CAMK1_CAMK1_ST	Q9UKV0	HDAC9	Q14012	CAMK1	S611	V606A	606	Missense	distal	-5	no	38.514	36.576	EPSD	COSMIC	32.882	Down-regulation
CAMK_CAMK1_CAMK1_ST	Q9UKV0	HDAC9	Q14012	CAMK1	S767	G768E	768	Missense	proximal	1	no	37.250	44.260	EPSD	COSMIC	32.882	Up-regulation
CAMK_CAMK1_CAMK1_ST	Q9UKV0	HDAC9	Q14012	CAMK1	S767	E769G	769	Missense	proximal	2	no	37.250	36.912	EPSD	COSMIC	32.882	Down-regulation
CAMK_CAMK1_CAMK1_ST	Q9UKV0	HDAC9	Q14012	CAMK1	S767	L770M	770	Missense	distal	3	no	37.250	37.252	EPSD	COSMIC	32.882	Up-regulation
TK_Src_SrcA_YES1_Y	P09917	ALOX5	P07947	YES1	Y446	R439K	439	Missense	distal	-7	no	20.656	20.688	EPSD;PhosphoSitePlus	COSMIC	16.372	Up-regulation
TK_Src_SrcA_YES1_Y	Q05397	PTK2	P07947	YES1	Y407	D402V	402	Missense	distal	-5	no	18.472	18.098	EPSD	COSMIC	16.372	Down-regulation
TK_Src_SrcA_YES1_Y	Q05397	PTK2	P07947	YES1	Y407	D405G	405	Missense	proximal	-2	no	18.472	18.463	EPSD	COSMIC	16.372	Down-regulation
TK_Src_SrcA_YES1_Y	Q05397	PTK2	P07947	YES1	Y407	R413S	413	Missense	distal	6	no	18.472	17.019	EPSD	COSMIC	16.372	Down-regulation
TK_Src_SrcA_YES1_Y	Q05397	PTK2	P07947	YES1	Y407	E404A	404	Missense	distal	-3	no	18.472	22.575	EPSD	COSMIC	16.372	Up-regulation
TK_Src_SrcA_YES1_Y	Q05397	PTK2	P07947	YES1	Y576	R569L	569	Missense	distal	-7	no	26.056	26.020	EPSD	COSMIC	16.372	Down-regulation
TK_Src_SrcA_YES1_Y	Q05397	PTK2	P07947	YES1	Y576	A579V	579	Missense	distal	3	no	26.056	24.844	EPSD	COSMIC	16.372	Down-regulation
TK_Src_SrcA_YES1_Y	Q05397	PTK2	P07947	YES1	Y861	D868N	868	Missense	distal	7	no	28.135	28.339	EPSD;PhosphoSitePlus	COSMIC	16.372	Up-regulation
TK_Src_SrcA_YES1_Y	Q05397	PTK2	P07947	YES1	Y861	G865C	865	Missense	distal	4	no	28.135	28.095	EPSD;PhosphoSitePlus	COSMIC	16.372	Down-regulation
TK_Src_SrcA_YES1_Y	Q05397	PTK2	P07947	YES1	Y925	G930C	930	Missense	distal	5	no	29.173	28.522	PhosphoSitePlus;EPSD	COSMIC	16.372	Down-regulation
TK_Src_SrcA_YES1_Y	Q05397	PTK2	P07947	YES1	Y925	E926K	926	Missense	proximal	1	no	29.173	26.416	PhosphoSitePlus;EPSD	COSMIC	16.372	Down-regulation
TK_Src_SrcA_YES1_Y	Q05397	PTK2	P07947	YES1	Y925	Y925C	925	Missense	central	0	yes	29.173	0.000	PhosphoSitePlus;EPSD	COSMIC	16.372	Loss
TK_Src_SrcA_YES1_Y	Q05397	PTK2	P07947	YES1	Y925	R919L	919	Missense	distal	-6	no	29.173	29.878	PhosphoSitePlus;EPSD	COSMIC	16.372	Up-regulation
TK_Src_SrcA_YES1_Y	Q05397	PTK2	P07947	YES1	Y925	R919Q	919	Missense	distal	-6	no	29.173	29.260	PhosphoSitePlus;EPSD	COSMIC	16.372	Up-regulation
TK_Src_SrcA_YES1_Y	O60500	NPHS1	P07947	YES1	Y1193	G1190V	1190	Missense	distal	-3	no	13.755	17.660	PhosphoSitePlus	COSMIC	16.372	Gain
TK_Src_SrcA_YES1_Y	P04626	ERBB2	P07947	YES1	Y781	G778D	778	Missense	distal	-3	no	9.434	18.464	EPSD	COSMIC	16.372	Gain
TK_Src_SrcA_YES1_Y	P04626	ERBB2	P07947	YES1	Y923	A928T	928	Missense	distal	5	no	19.455	18.034	EPSD	COSMIC	16.372	Down-regulation
TK_Src_SrcA_YES1_Y	P04626	ERBB2	P07947	YES1	Y923	G925V	925	Missense	proximal	2	no	19.455	19.673	EPSD	COSMIC	16.372	Up-regulation
TK_Src_SrcA_YES1_Y	P04626	ERBB2	P07947	YES1	Y923	E930D	930	Missense	distal	7	no	19.455	18.893	EPSD	COSMIC;GDSC	16.372	Down-regulation
TK_Src_SrcA_YES1_Y	P04626	ERBB2	P07947	YES1	Y923	R929Q	929	Missense	distal	6	no	19.455	17.159	EPSD	COSMIC	16.372	Down-regulation
TK_Src_SrcA_YES1_Y	P04626	ERBB2	P07947	YES1	Y923	D924N	924	Missense	proximal	1	no	19.455	19.682	EPSD	COSMIC	16.372	Up-regulation
TK_Src_SrcA_YES1_Y	P04626	ERBB2	P07947	YES1	Y923	P927S	927	Missense	distal	4	no	19.455	19.322	EPSD	COSMIC	16.372	Down-regulation
TK_Src_SrcA_YES1_Y	P04626	ERBB2	P07947	YES1	Y923	T917S	917	Missense	distal	-6	no	19.455	19.401	EPSD	COSMIC	16.372	Down-regulation
TK_Src_SrcA_YES1_Y	P04626	ERBB2	P07947	YES1	Y923	P927Q	927	Missense	distal	4	no	19.455	19.571	EPSD	COSMIC	16.372	Up-regulation
TK_Src_SrcA_YES1_Y	P04626	ERBB2	P07947	YES1	Y1005	D1012N	1012	Missense	distal	7	no	17.646	17.849	EPSD	COSMIC	16.372	Up-regulation
TK_Src_SrcA_YES1_Y	P04626	ERBB2	P07947	YES1	Y1221	A1216D	1216	Missense	distal	-5	no	22.614	23.124	EPSD	COSMIC	16.372	Up-regulation
TK_Src_SrcA_YES1_Y	P04626	ERBB2	P07947	YES1	Y1221	P1227S	1227	Missense	distal	6	no	22.614	18.581	EPSD	COSMIC	16.372	Down-regulation
TK_Src_SrcA_YES1_Y	P04626	ERBB2	P07947	YES1	Y1222	A1216D	1216	Missense	distal	-6	no	16.726	17.123	EPSD	COSMIC	16.372	Up-regulation
TK_Src_SrcA_YES1_Y	P04626	ERBB2	P07947	YES1	Y1222	E1229Q	1229	Missense	distal	7	no	16.726	16.583	EPSD	COSMIC	16.372	Down-regulation
TK_Src_SrcA_YES1_Y	P04626	ERBB2	P07947	YES1	Y1222	E1229D	1229	Missense	distal	7	no	16.726	16.164	EPSD	COSMIC	16.372	Loss
TK_Src_SrcA_YES1_Y	P04626	ERBB2	P07947	YES1	Y1222	P1227S	1227	Missense	distal	5	no	16.726	15.786	EPSD	COSMIC	16.372	Loss
TK_Src_SrcA_YES1_Y	P04626	ERBB2	P07947	YES1	Y1248	N1245D	1245	Missense	distal	-3	no	16.654	21.062	EPSD	COSMIC	16.372	Up-regulation
TK_Src_SrcA_YES1_Y	P04626	ERBB2	P07947	YES1	Y1248	G1250S	1250	Missense	proximal	2	no	16.654	16.836	EPSD	COSMIC	16.372	Up-regulation
TK_Src_SrcA_YES1_Y	P04626	ERBB2	P07947	YES1	Y1248	P1254S	1254	Missense	distal	6	no	16.654	12.621	EPSD	COSMIC	16.372	Loss
TK_Src_SrcA_YES1_Y	P04626	ERBB2	P07947	YES1	Y1248	E1244D	1244	Missense	distal	-4	no	16.654	16.962	EPSD	COSMIC	16.372	Up-regulation
TK_Src_SrcA_YES1_Y	P04626	ERBB2	P07947	YES1	Y1248	T1242M	1242	Missense	distal	-6	no	16.654	16.700	EPSD	COSMIC	16.372	Up-regulation
TK_Src_SrcA_YES1_Y	Q969T9	WBP2	P07947	YES1	Y192	Y192H	192	Missense	central	0	yes	34.604	0.000	EPSD;PhosphoSitePlus	COSMIC	16.372	Loss
TK_Src_SrcA_YES1_Y	Q969T9	WBP2	P07947	YES1	Y192	P198Q	198	Missense	distal	6	no	34.604	29.727	EPSD;PhosphoSitePlus	COSMIC	16.372	Down-regulation
TK_Src_SrcA_YES1_Y	Q969T9	WBP2	P07947	YES1	Y192	P195S	195	Missense	distal	3	no	34.604	32.641	EPSD;PhosphoSitePlus	COSMIC	16.372	Down-regulation
TK_Src_SrcA_YES1_Y	Q969T9	WBP2	P07947	YES1	Y231	P237L	237	Missense	distal	6	no	27.279	21.753	PhosphoSitePlus;EPSD	COSMIC	16.372	Down-regulation
TK_Src_SrcA_YES1_Y	Q969T9	WBP2	P07947	YES1	Y241	P237L	237	Missense	distal	-4	no	17.240	13.935	EPSD	COSMIC	16.372	Loss
TK_Src_SrcA_YES1_Y	P46527	CDKN1B	P07947	YES1	Y74	G72A	72	Missense	proximal	-2	no	31.675	31.752	EPSD;PhosphoSitePlus	COSMIC	16.372	Up-regulation
TK_Src_SrcA_YES1_Y	P46527	CDKN1B	P07947	YES1	Y74	E71K	71	Missense	distal	-3	no	31.675	26.834	EPSD;PhosphoSitePlus	COSMIC	16.372	Down-regulation
TK_Src_SrcA_YES1_Y	P46527	CDKN1B	P07947	YES1	Y74	L70R	70	Missense	distal	-4	no	31.675	34.259	EPSD;PhosphoSitePlus	COSMIC	16.372	Up-regulation
TK_Src_SrcA_YES1_Y	P46527	CDKN1B	P07947	YES1	Y74	P69L	69	Missense	distal	-5	no	31.675	32.210	EPSD;PhosphoSitePlus	COSMIC	16.372	Up-regulation
TK_Src_SrcA_YES1_Y	P46527	CDKN1B	P07947	YES1	Y74	E80Q	80	Missense	distal	6	no	31.675	30.403	EPSD;PhosphoSitePlus	COSMIC	16.372	Down-regulation
TK_Src_SrcA_YES1_Y	P46527	CDKN1B	P07947	YES1	Y74	W76G	76	Missense	proximal	2	no	31.675	31.840	EPSD;PhosphoSitePlus	COSMIC	16.372	Up-regulation
TK_Src_SrcA_YES1_Y	P46527	CDKN1B	P07947	YES1	Y88	P91S	91	Missense	distal	3	no	30.194	28.231	EPSD;PhosphoSitePlus	COSMIC	16.372	Down-regulation
TK_Src_SrcA_YES1_Y	P46527	CDKN1B	P07947	YES1	Y88	R90K	90	Missense	proximal	2	no	30.194	30.457	EPSD;PhosphoSitePlus	COSMIC	16.372	Up-regulation
TK_Src_SrcA_YES1_Y	P46527	CDKN1B	P07947	YES1	Y88	R93W	93	Missense	distal	5	no	30.194	29.476	EPSD;PhosphoSitePlus	COSMIC	16.372	Down-regulation
TK_Src_SrcA_YES1_Y	P46527	CDKN1B	P07947	YES1	Y88	P94L	94	Missense	distal	6	no	30.194	24.668	EPSD;PhosphoSitePlus	COSMIC	16.372	Down-regulation
TK_Src_SrcA_YES1_Y	P46527	CDKN1B	P07947	YES1	Y88	Y88C	88	Missense	central	0	yes	30.194	0.000	EPSD;PhosphoSitePlus	COSMIC	16.372	Loss
TK_Src_SrcA_YES1_Y	P46527	CDKN1B	P07947	YES1	Y89	P91S	91	Missense	proximal	2	no	28.772	28.620	PhosphoSitePlus;EPSD	COSMIC	16.372	Down-regulation
TK_Src_SrcA_YES1_Y	P46527	CDKN1B	P07947	YES1	Y89	R90K	90	Missense	proximal	1	no	28.772	29.742	PhosphoSitePlus;EPSD	COSMIC	16.372	Up-regulation
TK_Src_SrcA_YES1_Y	P46527	CDKN1B	P07947	YES1	Y89	R93W	93	Missense	distal	4	no	28.772	28.348	PhosphoSitePlus;EPSD	COSMIC	16.372	Down-regulation
TK_Src_SrcA_YES1_Y	P46527	CDKN1B	P07947	YES1	Y89	P94L	94	Missense	distal	5	no	28.772	26.979	PhosphoSitePlus;EPSD	COSMIC	16.372	Down-regulation
TK_Src_SrcA_YES1_Y	P46527	CDKN1B	P07947	YES1	Y89	Y88C	88	Missense	proximal	-1	no	28.772	29.069	PhosphoSitePlus;EPSD	COSMIC	16.372	Up-regulation
TK_Src_SrcA_YES1_Y	Q16555	DPYSL2	P07947	YES1	Y479	R481H	481	Missense	proximal	2	no	31.780	31.588	PhosphoSitePlus	COSMIC	16.372	Down-regulation
TK_Src_SrcA_YES1_Y	Q16555	DPYSL2	P07947	YES1	Y479	R481C	481	Missense	proximal	2	no	31.780	31.750	PhosphoSitePlus	COSMIC	16.372	Down-regulation
TK_Src_SrcA_YES1_Y	Q16555	DPYSL2	P07947	YES1	Y499	R496Q	496	Missense	distal	-3	no	14.589	19.423	EPSD	COSMIC	16.372	Gain
TK_Src_SrcA_YES1_Y	Q16555	DPYSL2	P07947	YES1	Y499	V506A	506	Missense	distal	7	no	14.589	17.132	EPSD	COSMIC	16.372	Gain
TK_Src_SrcA_YES1_Y	P14921	ETS1	P07947	YES1	Y140	V137I	137	Missense	distal	-3	no	20.759	13.451	EPSD	COSMIC	16.372	Loss
TK_Src_SrcA_YES1_Y	P14921	ETS1	P07947	YES1	Y140	K134N	134	Missense	distal	-6	no	20.759	20.716	EPSD	COSMIC	16.372	Down-regulation
TK_Src_SrcA_YES1_Y	P14921	ETS1	P07947	YES1	Y140	E135D	135	Missense	distal	-5	no	20.759	20.864	EPSD	COSMIC	16.372	Up-regulation
TK_Src_SrcA_YES1_Y	P14921	ETS1	P07947	YES1	Y140	K134T	134	Missense	distal	-6	no	20.759	20.960	EPSD	COSMIC	16.372	Up-regulation
TK_Src_SrcA_YES1_Y	P14921	ETS1	P07947	YES1	Y283	D287N	287	Missense	distal	4	no	22.413	22.586	PhosphoSitePlus	COSMIC	16.372	Up-regulation
TK_Src_SrcA_YES1_Y	P14921	ETS1	P07947	YES1	Y283	R279H	279	Missense	distal	-4	no	22.413	20.320	PhosphoSitePlus	COSMIC;CCLE	16.372	Down-regulation
TK_Src_SrcA_YES1_Y	P14921	ETS1	P07947	YES1	Y283	Q278K	278	Missense	distal	-5	no	22.413	22.565	PhosphoSitePlus	COSMIC	16.372	Up-regulation
TK_Src_SrcA_YES1_Y	P14921	ETS1	P07947	YES1	Y283	L277R	277	Missense	distal	-6	no	22.413	21.708	PhosphoSitePlus	COSMIC	16.372	Down-regulation
TK_Src_SrcA_YES1_Y	P14921	ETS1	P07947	YES1	Y283	R279C	279	Missense	distal	-4	no	22.413	21.399	PhosphoSitePlus	COSMIC	16.372	Down-regulation
TK_Src_SrcA_YES1_Y	Q16543	CDC37	P07947	YES1	Y155	H161R	161	Missense	distal	6	no	14.706	18.897	EPSD	COSMIC;CCLE	16.372	Gain
TK_Src_SrcA_YES1_Y	Q16543	CDC37	P07947	YES1	Y298	P302H	302	Missense	distal	4	no	29.701	29.475	PhosphoSitePlus	COSMIC;CCLE	16.372	Down-regulation
TK_Src_SrcA_YES1_Y	P11802	CDK4	P07947	YES1	Y17	A10D	10	Missense	distal	-7	no	28.759	28.707	PhosphoSitePlus	COSMIC	16.372	Down-regulation
TK_Src_SrcA_YES1_Y	P11802	CDK4	P07947	YES1	Y17	K22R	22	Missense	distal	5	no	28.759	28.669	PhosphoSitePlus	COSMIC	16.372	Down-regulation
TK_Src_SrcA_YES1_Y	P11802	CDK4	P07947	YES1	Y17	A23T	23	Missense	distal	6	no	28.759	24.836	PhosphoSitePlus	COSMIC	16.372	Down-regulation
TK_Src_SrcA_YES1_Y	P11802	CDK4	P07947	YES1	Y165	Q168E	168	Missense	distal	3	no	17.679	18.357	EPSD	COSMIC	16.372	Up-regulation
TK_Src_SrcA_YES1_Y	P11802	CDK4	P07947	YES1	Y165	D158Y	158	Missense	distal	-7	no	17.679	17.665	EPSD	COSMIC	16.372	Down-regulation
TK_Src_SrcA_YES1_Y	P11802	CDK4	P07947	YES1	Y165	T172R	172	Missense	distal	7	no	17.679	18.730	EPSD	COSMIC	16.372	Up-regulation
TK_Src_SrcA_YES1_Y	P11802	CDK4	P07947	YES1	Y165	L161M	161	Missense	distal	-4	no	17.679	18.166	EPSD	COSMIC	16.372	Up-regulation
Other_IKK_TBK1_ST	Q96FA3	PELI1	Q9UHD2	TBK1	S125	S123R	123	Missense	proximal	-2	no	148.101	147.221	EPSD	COSMIC	145.681	Down-regulation
Other_IKK_TBK1_ST	Q96FA3	PELI1	Q9UHD2	TBK1	S293	R296K	296	Missense	distal	3	no	183.079	183.571	EPSD;PhosphoSitePlus	COSMIC	145.681	Up-regulation
Other_IKK_TBK1_ST	Q13501	SQSTM1	Q9UHD2	TBK1	S182	R183C	183	Missense	proximal	1	no	146.626	108.606	EPSD	COSMIC	145.681	Loss
Other_IKK_TBK1_ST	Q13501	SQSTM1	Q9UHD2	TBK1	S229	S226F	226	Missense	distal	-3	no	146.836	137.884	EPSD	COSMIC	145.681	Loss
Other_IKK_TBK1_ST	Q13501	SQSTM1	Q9UHD2	TBK1	S272	E274D	274	Missense	proximal	2	no	160.990	161.789	EPSD	COSMIC	145.681	Up-regulation
Other_IKK_TBK1_ST	Q13501	SQSTM1	Q9UHD2	TBK1	S275	E274D	274	Missense	proximal	-1	no	154.122	153.778	EPSD	COSMIC	145.681	Down-regulation
Other_IKK_TBK1_ST	Q13501	SQSTM1	Q9UHD2	TBK1	S276	E274D	274	Missense	proximal	-2	no	158.047	158.402	EPSD	COSMIC	145.681	Up-regulation
Other_IKK_TBK1_ST	Q13501	SQSTM1	Q9UHD2	TBK1	S288	C289Y	289	Missense	proximal	1	no	116.880	164.756	EPSD	COSMIC;GDSC;CCLE	145.681	Gain
Other_IKK_TBK1_ST	Q13501	SQSTM1	Q9UHD2	TBK1	S355	P359S	359	Missense	distal	4	no	155.173	161.395	EPSD	COSMIC	145.681	Up-regulation
Other_IKK_TBK1_ST	Q13501	SQSTM1	Q9UHD2	TBK1	S355	E362D	362	Missense	distal	7	no	155.173	155.148	EPSD	COSMIC	145.681	Down-regulation
Other_IKK_TBK1_ST	Q13501	SQSTM1	Q9UHD2	TBK1	S355	T350I	350	Missense	distal	-5	no	155.173	155.031	EPSD	COSMIC	145.681	Down-regulation
Other_IKK_TBK1_ST	Q13501	SQSTM1	Q9UHD2	TBK1	S355	E360K	360	Missense	distal	5	no	155.173	154.196	EPSD	COSMIC	145.681	Down-regulation
Other_IKK_TBK1_ST	Q13501	SQSTM1	Q9UHD2	TBK1	S365	P359S	359	Missense	distal	-6	no	156.094	170.543	EPSD	COSMIC	145.681	Up-regulation
Other_IKK_TBK1_ST	Q13501	SQSTM1	Q9UHD2	TBK1	S365	E362D	362	Missense	distal	-3	no	156.094	158.518	EPSD	COSMIC	145.681	Up-regulation
Other_IKK_TBK1_ST	Q13501	SQSTM1	Q9UHD2	TBK1	S365	S365N	365	Missense	central	0	yes	156.094	0.000	EPSD	COSMIC	145.681	Loss
Other_IKK_TBK1_ST	Q13501	SQSTM1	Q9UHD2	TBK1	S365	E360K	360	Missense	distal	-5	no	156.094	156.122	EPSD	COSMIC	145.681	Up-regulation
Other_IKK_TBK1_ST	Q13501	SQSTM1	Q9UHD2	TBK1	S365	P364S	364	Missense	proximal	-1	no	156.094	155.692	EPSD	COSMIC	145.681	Down-regulation
Other_IKK_TBK1_ST	Q13501	SQSTM1	Q9UHD2	TBK1	S366	P359S	359	Missense	distal	-7	no	155.023	155.536	EPSD	COSMIC	145.681	Up-regulation
Other_IKK_TBK1_ST	Q13501	SQSTM1	Q9UHD2	TBK1	S366	E362D	362	Missense	distal	-4	no	155.023	155.562	EPSD	COSMIC	145.681	Up-regulation
Other_IKK_TBK1_ST	Q13501	SQSTM1	Q9UHD2	TBK1	S366	S365N	365	Missense	proximal	-1	no	155.023	156.280	EPSD	COSMIC	145.681	Up-regulation
Other_IKK_TBK1_ST	Q13501	SQSTM1	Q9UHD2	TBK1	S366	E360K	360	Missense	distal	-6	no	155.023	152.246	EPSD	COSMIC	145.681	Down-regulation
Other_IKK_TBK1_ST	Q13501	SQSTM1	Q9UHD2	TBK1	S366	P364S	364	Missense	proximal	-2	no	155.023	156.113	EPSD	COSMIC	145.681	Up-regulation
Other_IKK_TBK1_ST	Q13501	SQSTM1	Q9UHD2	TBK1	S403	S403F	403	Missense	central	0	yes	177.440	0.000	PhosphoSitePlus	COSMIC	145.681	Loss
Other_IKK_TBK1_ST	Q96CV9	OPTN	Q9UHD2	TBK1	S308	N303K	303	Missense	distal	-5	no	145.900	146.364	EPSD	COSMIC	145.681	Up-regulation
Other_IKK_TBK1_ST	Q96CV9	OPTN	Q9UHD2	TBK1	S513	E507K	507	Missense	distal	-6	no	179.077	176.300	EPSD;PhosphoSitePlus	COSMIC	145.681	Down-regulation
Other_IKK_TBK1_ST	Q96CV9	OPTN	Q9UHD2	TBK1	S519	R524K	524	Missense	distal	5	no	150.700	148.606	EPSD	COSMIC;GDSC;CCLE	145.681	Down-regulation
Other_IKK_TBK1_ST	P23443	RPS6KB1	Q9UHD2	TBK1	T252	H245Y	245	Missense	distal	-7	no	145.889	145.814	EPSD	COSMIC	145.681	Down-regulation
Other_IKK_TBK1_ST	P23443	RPS6KB1	Q9UHD2	TBK1	T387	P391S	391	Missense	distal	4	no	159.307	165.529	EPSD	COSMIC	145.681	Up-regulation
Other_IKK_TBK1_ST	P23443	RPS6KB1	Q9UHD2	TBK1	T387	R388G	388	Missense	proximal	1	no	159.307	149.768	EPSD	COSMIC	145.681	Down-regulation
Other_IKK_TBK1_ST	P23443	RPS6KB1	Q9UHD2	TBK1	T390	P391S	391	Missense	proximal	1	no	158.953	150.619	EPSD	COSMIC	145.681	Down-regulation
Other_IKK_TBK1_ST	P23443	RPS6KB1	Q9UHD2	TBK1	T390	R388G	388	Missense	proximal	-2	no	158.953	158.226	EPSD	COSMIC	145.681	Down-regulation
Other_IKK_TBK1_ST	P23443	RPS6KB1	Q9UHD2	TBK1	T412	T412A	412	Missense	central	0	yes	153.850	0.000	EPSD	COSMIC	145.681	Loss
Other_IKK_TBK1_ST	P23443	RPS6KB1	Q9UHD2	TBK1	T412	V414E	414	Missense	proximal	2	no	153.850	151.929	EPSD	COSMIC	145.681	Down-regulation
Other_IKK_TBK1_ST	P23443	RPS6KB1	Q9UHD2	TBK1	S427	I432T	432	Missense	distal	5	no	167.277	168.664	EPSD	COSMIC	145.681	Up-regulation
Other_IKK_TBK1_ST	P23443	RPS6KB1	Q9UHD2	TBK1	S427	E429Q	429	Missense	proximal	2	no	167.277	165.435	EPSD	COSMIC	145.681	Down-regulation
Other_IKK_TBK1_ST	P23443	RPS6KB1	Q9UHD2	TBK1	T444	G440A	440	Missense	distal	-4	no	169.595	170.708	EPSD;PhosphoSitePlus	COSMIC	145.681	Up-regulation
Other_IKK_TBK1_ST	P23443	RPS6KB1	Q9UHD2	TBK1	T444	P445L	445	Missense	proximal	1	no	169.595	176.664	EPSD;PhosphoSitePlus	COSMIC	145.681	Up-regulation
Other_IKK_TBK1_ST	P23443	RPS6KB1	Q9UHD2	TBK1	S447	G440A	440	Missense	distal	-7	no	187.584	189.935	PhosphoSitePlus;EPSD	COSMIC	145.681	Up-regulation
Other_IKK_TBK1_ST	P23443	RPS6KB1	Q9UHD2	TBK1	S447	P445L	445	Missense	proximal	-2	no	187.584	188.522	PhosphoSitePlus;EPSD	COSMIC	145.681	Up-regulation
Other_IKK_TBK1_ST	P23443	RPS6KB1	Q9UHD2	TBK1	S447	G454W	454	Missense	distal	7	no	187.584	187.644	PhosphoSitePlus;EPSD	COSMIC	145.681	Up-regulation
Other_IKK_TBK1_ST	P23443	RPS6KB1	Q9UHD2	TBK1	S503	G504R	504	Missense	proximal	1	no	143.163	152.702	EPSD	COSMIC	145.681	Gain
Other_IKK_TBK1_ST	P23443	RPS6KB1	Q9UHD2	TBK1	S503	K508Q	508	Missense	distal	5	no	143.163	145.709	EPSD	COSMIC	145.681	Gain
Other_IKK_TBK1_ST	Q8TEV9	SMCR8	Q9UHD2	TBK1	S402	C406Y	406	Missense	distal	4	no	173.904	172.536	EPSD;PhosphoSitePlus	COSMIC	145.681	Down-regulation
Other_IKK_TBK1_ST	Q8TEV9	SMCR8	Q9UHD2	TBK1	S402	S401R	401	Missense	proximal	-1	no	173.904	174.133	EPSD;PhosphoSitePlus	COSMIC	145.681	Up-regulation
Other_IKK_TBK1_ST	Q8TEV9	SMCR8	Q9UHD2	TBK1	S402	D396N	396	Missense	distal	-6	no	173.904	169.751	EPSD;PhosphoSitePlus	COSMIC	145.681	Down-regulation
Other_IKK_TBK1_ST	Q8TEV9	SMCR8	Q9UHD2	TBK1	S402	S401N	401	Missense	proximal	-1	no	173.904	175.160	EPSD;PhosphoSitePlus	COSMIC;GDSC;CCLE	145.681	Up-regulation
Other_IKK_TBK1_ST	Q8TEV9	SMCR8	Q9UHD2	TBK1	S402	P407L	407	Missense	distal	5	no	173.904	172.875	EPSD;PhosphoSitePlus	COSMIC	145.681	Down-regulation
Other_IKK_TBK1_ST	Q8TEV9	SMCR8	Q9UHD2	TBK1	S417	V422G	422	Missense	distal	5	no	147.876	144.135	EPSD	COSMIC	145.681	Loss
Other_IKK_TBK1_ST	Q8TEV9	SMCR8	Q9UHD2	TBK1	T511	R510M	510	Missense	proximal	-1	no	147.255	147.103	EPSD	COSMIC	145.681	Down-regulation
Other_IKK_TBK1_ST	Q8TEV9	SMCR8	Q9UHD2	TBK1	S513	R510M	510	Missense	distal	-3	no	146.784	148.650	EPSD	COSMIC	145.681	Up-regulation
Other_IKK_TBK1_ST	Q8TEV9	SMCR8	Q9UHD2	TBK1	S516	T522I	522	Missense	distal	6	no	159.533	160.291	EPSD	COSMIC	145.681	Up-regulation
Other_IKK_TBK1_ST	Q8TEV9	SMCR8	Q9UHD2	TBK1	S516	R510M	510	Missense	distal	-6	no	159.533	150.822	EPSD	COSMIC	145.681	Down-regulation
Other_IKK_TBK1_ST	Q8TEV9	SMCR8	Q9UHD2	TBK1	S516	S521G	521	Missense	distal	5	no	159.533	155.929	EPSD	COSMIC	145.681	Down-regulation
Other_IKK_TBK1_ST	Q8TEV9	SMCR8	Q9UHD2	TBK1	S521	T522I	522	Missense	proximal	1	no	131.235	176.502	EPSD	COSMIC	145.681	Gain
Other_IKK_TBK1_ST	Q8TEV9	SMCR8	Q9UHD2	TBK1	S698	K703N	703	Missense	distal	5	no	158.080	158.144	EPSD	COSMIC	145.681	Up-regulation
Other_IKK_TBK1_ST	Q14653	IRF3	Q9UHD2	TBK1	S123	P124L	124	Missense	proximal	1	no	141.209	148.278	EPSD	COSMIC	145.681	Gain
Other_IKK_TBK1_ST	Q14653	IRF3	Q9UHD2	TBK1	S173	Q169R	169	Missense	distal	-4	no	174.935	173.922	EPSD;PhosphoSitePlus	COSMIC;CCLE	145.681	Down-regulation
Other_IKK_TBK1_ST	Q14653	IRF3	Q9UHD2	TBK1	S173	P166S	166	Missense	distal	-7	no	174.935	175.448	EPSD;PhosphoSitePlus	COSMIC	145.681	Up-regulation
Other_IKK_TBK1_ST	Q14653	IRF3	Q9UHD2	TBK1	S175	Q169R	169	Missense	distal	-6	no	184.189	178.042	EPSD;PhosphoSitePlus	COSMIC;CCLE	145.681	Down-regulation
Other_IKK_TBK1_ST	Q14653	IRF3	Q9UHD2	TBK1	S259	R262G	262	Missense	distal	3	no	149.360	149.857	EPSD	COSMIC;GDSC;CCLE	145.681	Up-regulation
Other_IKK_TBK1_ST	Q14653	IRF3	Q9UHD2	TBK1	S259	V261E	261	Missense	proximal	2	no	149.360	147.439	EPSD	COSMIC	145.681	Down-regulation
Other_IKK_TBK1_ST	Q14653	IRF3	Q9UHD2	TBK1	S339	G335E	335	Missense	distal	-4	no	165.824	166.188	EPSD	COSMIC	145.681	Up-regulation
Other_IKK_TBK1_ST	Q14653	IRF3	Q9UHD2	TBK1	S339	R341C	341	Missense	proximal	2	no	165.824	164.331	EPSD	COSMIC	145.681	Down-regulation
Other_IKK_TBK1_ST	Q14653	IRF3	Q9UHD2	TBK1	S339	G337A	337	Missense	proximal	-2	no	165.824	166.428	EPSD	COSMIC	145.681	Up-regulation
Other_IKK_TBK1_ST	Q14653	IRF3	Q9UHD2	TBK1	S339	G335V	335	Missense	distal	-4	no	165.824	166.231	EPSD	COSMIC	145.681	Up-regulation
Other_IKK_TBK1_ST	Q14653	IRF3	Q9UHD2	TBK1	S385	R380W	380	Missense	distal	-5	no	181.022	179.201	EPSD;PhosphoSitePlus	COSMIC	145.681	Down-regulation
Other_IKK_TBK1_ST	Q14653	IRF3	Q9UHD2	TBK1	S385	T390I	390	Missense	distal	5	no	181.022	179.635	EPSD;PhosphoSitePlus	COSMIC	145.681	Down-regulation
Other_IKK_TBK1_ST	Q14653	IRF3	Q9UHD2	TBK1	S385	T390P	390	Missense	distal	5	no	181.022	181.308	EPSD;PhosphoSitePlus	COSMIC	145.681	Up-regulation
Other_IKK_TBK1_ST	Q14653	IRF3	Q9UHD2	TBK1	S385	E388D	388	Missense	distal	3	no	181.022	181.748	EPSD;PhosphoSitePlus	COSMIC	145.681	Up-regulation
Other_IKK_TBK1_ST	Q14653	IRF3	Q9UHD2	TBK1	S386	R380W	380	Missense	distal	-6	no	184.690	159.245	EPSD;PhosphoSitePlus	COSMIC	145.681	Down-regulation
Other_IKK_TBK1_ST	Q14653	IRF3	Q9UHD2	TBK1	S386	T390I	390	Missense	distal	4	no	184.690	181.017	EPSD;PhosphoSitePlus	COSMIC	145.681	Down-regulation
Other_IKK_TBK1_ST	Q14653	IRF3	Q9UHD2	TBK1	S386	T390P	390	Missense	distal	4	no	184.690	181.352	EPSD;PhosphoSitePlus	COSMIC	145.681	Down-regulation
Other_IKK_TBK1_ST	Q14653	IRF3	Q9UHD2	TBK1	S386	E388D	388	Missense	proximal	2	no	184.690	185.490	EPSD;PhosphoSitePlus	COSMIC	145.681	Up-regulation
Other_IKK_TBK1_ST	Q14653	IRF3	Q9UHD2	TBK1	T390	T390I	390	Missense	central	0	yes	156.230	0.000	EPSD	COSMIC	145.681	Loss
Other_IKK_TBK1_ST	Q14653	IRF3	Q9UHD2	TBK1	T390	T390P	390	Missense	central	0	yes	156.230	0.000	EPSD	COSMIC	145.681	Loss
Other_IKK_TBK1_ST	Q14653	IRF3	Q9UHD2	TBK1	T390	E388D	388	Missense	proximal	-2	no	156.230	156.585	EPSD	COSMIC	145.681	Up-regulation
Other_IKK_TBK1_ST	Q14653	IRF3	Q9UHD2	TBK1	S396	T390I	390	Missense	distal	-6	no	177.185	172.527	EPSD;PhosphoSitePlus	COSMIC	145.681	Down-regulation
Other_IKK_TBK1_ST	Q14653	IRF3	Q9UHD2	TBK1	S396	T390P	390	Missense	distal	-6	no	177.185	170.798	EPSD;PhosphoSitePlus	COSMIC	145.681	Down-regulation
Other_IKK_TBK1_ST	Q14653	IRF3	Q9UHD2	TBK1	S396	P400Q	400	Missense	distal	4	no	177.185	179.387	EPSD;PhosphoSitePlus	COSMIC	145.681	Up-regulation
Other_IKK_TBK1_ST	Q14653	IRF3	Q9UHD2	TBK1	S396	P400T	400	Missense	distal	4	no	177.185	180.523	EPSD;PhosphoSitePlus	COSMIC	145.681	Up-regulation
Other_IKK_TBK1_ST	Q14653	IRF3	Q9UHD2	TBK1	S398	P400Q	400	Missense	proximal	2	no	172.439	174.081	EPSD;PhosphoSitePlus	COSMIC	145.681	Up-regulation
Other_IKK_TBK1_ST	Q14653	IRF3	Q9UHD2	TBK1	S398	P400T	400	Missense	proximal	2	no	172.439	178.298	EPSD;PhosphoSitePlus	COSMIC	145.681	Up-regulation
Other_IKK_TBK1_ST	Q14653	IRF3	Q9UHD2	TBK1	S402	D406E	406	Missense	distal	4	no	162.905	164.212	EPSD;PhosphoSitePlus	COSMIC	145.681	Up-regulation
Other_IKK_TBK1_ST	Q14653	IRF3	Q9UHD2	TBK1	S402	P400Q	400	Missense	proximal	-2	no	162.905	163.711	EPSD;PhosphoSitePlus	COSMIC	145.681	Up-regulation
Other_IKK_TBK1_ST	Q14653	IRF3	Q9UHD2	TBK1	S402	P400T	400	Missense	proximal	-2	no	162.905	163.382	EPSD;PhosphoSitePlus	COSMIC	145.681	Up-regulation
Other_IKK_TBK1_ST	Q14653	IRF3	Q9UHD2	TBK1	T404	Y411S	411	Missense	distal	7	no	160.981	160.930	PhosphoSitePlus;EPSD	COSMIC	145.681	Down-regulation
Other_IKK_TBK1_ST	Q14653	IRF3	Q9UHD2	TBK1	T404	D406E	406	Missense	proximal	2	no	160.981	160.181	PhosphoSitePlus;EPSD	COSMIC	145.681	Down-regulation
Other_IKK_TBK1_ST	Q14653	IRF3	Q9UHD2	TBK1	T404	P400Q	400	Missense	distal	-4	no	160.981	160.863	PhosphoSitePlus;EPSD	COSMIC	145.681	Down-regulation
Other_IKK_TBK1_ST	Q14653	IRF3	Q9UHD2	TBK1	T404	P400T	400	Missense	distal	-4	no	160.981	160.771	PhosphoSitePlus;EPSD	COSMIC	145.681	Down-regulation
Other_IKK_TBK1_ST	Q14653	IRF3	Q9UHD2	TBK1	S405	Y411S	411	Missense	distal	6	no	172.742	181.370	EPSD;PhosphoSitePlus	COSMIC	145.681	Up-regulation
Other_IKK_TBK1_ST	Q14653	IRF3	Q9UHD2	TBK1	S405	D406E	406	Missense	proximal	1	no	172.742	166.145	EPSD;PhosphoSitePlus	COSMIC	145.681	Down-regulation
Other_IKK_TBK1_ST	Q14653	IRF3	Q9UHD2	TBK1	S405	P400Q	400	Missense	distal	-5	no	172.742	174.285	EPSD;PhosphoSitePlus	COSMIC	145.681	Up-regulation
Other_IKK_TBK1_ST	Q14653	IRF3	Q9UHD2	TBK1	S405	P400T	400	Missense	distal	-5	no	172.742	173.233	EPSD;PhosphoSitePlus	COSMIC	145.681	Up-regulation
Other_IKK_TBK1_ST	Q01094	E2F1	Q9UHD2	TBK1	S131	R127L	127	Missense	distal	-4	no	144.557	145.693	EPSD	COSMIC	145.681	Gain
Other_IKK_TBK1_ST	Q01094	E2F1	Q9UHD2	TBK1	T329	S336L	336	Missense	distal	7	no	145.979	145.973	EPSD	COSMIC	145.681	Down-regulation
Other_IKK_TBK1_ST	Q01094	E2F1	Q9UHD2	TBK1	T329	I330T	330	Missense	proximal	1	no	145.979	100.712	EPSD	COSMIC	145.681	Loss
Other_IKK_TBK1_ST	Q01094	E2F1	Q9UHD2	TBK1	T329	P335Q	335	Missense	distal	6	no	145.979	150.052	EPSD	COSMIC;GDSC;CCLE	145.681	Up-regulation
Other_IKK_TBK1_ST	Q01094	E2F1	Q9UHD2	TBK1	T329	P335S	335	Missense	distal	6	no	145.979	150.859	EPSD	COSMIC	145.681	Up-regulation
Other_IKK_TBK1_ST	Q01094	E2F1	Q9UHD2	TBK1	T329	P334L	334	Missense	distal	5	no	145.979	144.951	EPSD	COSMIC	145.681	Loss
Other_IKK_TBK1_ST	Q01094	E2F1	Q9UHD2	TBK1	S332	S336L	336	Missense	distal	4	no	179.631	176.052	PhosphoSitePlus	COSMIC	145.681	Down-regulation
Other_IKK_TBK1_ST	Q01094	E2F1	Q9UHD2	TBK1	S332	I330T	330	Missense	proximal	-2	no	179.631	180.046	PhosphoSitePlus	COSMIC	145.681	Up-regulation
Other_IKK_TBK1_ST	Q01094	E2F1	Q9UHD2	TBK1	S332	P335Q	335	Missense	distal	3	no	179.631	178.734	PhosphoSitePlus	COSMIC;GDSC;CCLE	145.681	Down-regulation
Other_IKK_TBK1_ST	Q01094	E2F1	Q9UHD2	TBK1	S332	P335S	335	Missense	distal	3	no	179.631	177.981	PhosphoSitePlus	COSMIC	145.681	Down-regulation
Other_IKK_TBK1_ST	Q01094	E2F1	Q9UHD2	TBK1	S332	P334L	334	Missense	proximal	2	no	179.631	182.506	PhosphoSitePlus	COSMIC	145.681	Up-regulation
Other_IKK_TBK1_ST	Q01094	E2F1	Q9UHD2	TBK1	S340	S341F	341	Missense	proximal	1	no	137.052	159.218	EPSD	COSMIC	145.681	Gain
Other_IKK_TBK1_ST	Q01094	E2F1	Q9UHD2	TBK1	S341	S341F	341	Missense	central	0	yes	156.414	0.000	EPSD	COSMIC	145.681	Loss
Other_IKK_TBK1_ST	Q01094	E2F1	Q9UHD2	TBK1	S341	P346S	346	Missense	distal	5	no	156.414	157.085	EPSD	COSMIC;GDSC	145.681	Up-regulation
Other_IKK_TBK1_ST	Q01094	E2F1	Q9UHD2	TBK1	S341	S336L	336	Missense	distal	-5	no	156.414	156.547	EPSD	COSMIC	145.681	Up-regulation
Other_IKK_TBK1_ST	Q01094	E2F1	Q9UHD2	TBK1	S341	P335Q	335	Missense	distal	-6	no	156.414	172.485	EPSD	COSMIC;GDSC;CCLE	145.681	Up-regulation
Other_IKK_TBK1_ST	Q01094	E2F1	Q9UHD2	TBK1	S341	P335S	335	Missense	distal	-6	no	156.414	170.863	EPSD	COSMIC	145.681	Up-regulation
Other_IKK_TBK1_ST	Q01094	E2F1	Q9UHD2	TBK1	S341	P334L	334	Missense	distal	-7	no	156.414	157.006	EPSD	COSMIC	145.681	Up-regulation
Other_IKK_TBK1_ST	Q01094	E2F1	Q9UHD2	TBK1	T344	S341F	341	Missense	distal	-3	no	154.924	145.972	EPSD	COSMIC	145.681	Down-regulation
Other_IKK_TBK1_ST	Q01094	E2F1	Q9UHD2	TBK1	T344	P346S	346	Missense	proximal	2	no	154.924	161.084	EPSD	COSMIC;GDSC	145.681	Up-regulation
Other_IKK_TBK1_ST	Q01094	E2F1	Q9UHD2	TBK1	T344	L350V	350	Missense	distal	6	no	154.924	160.513	EPSD	COSMIC	145.681	Up-regulation
Other_IKK_TBK1_ST	Q01094	E2F1	Q9UHD2	TBK1	S347	L350V	350	Missense	distal	3	no	145.460	146.017	EPSD	COSMIC	145.681	Gain
Other_IKK_TBK1_ST	Q01094	E2F1	Q9UHD2	TBK1	S349	P346S	346	Missense	distal	-3	no	145.505	149.769	EPSD	COSMIC;GDSC	145.681	Gain
Other_IKK_TBK1_ST	Q01094	E2F1	Q9UHD2	TBK1	S352	P346S	346	Missense	distal	-6	no	142.453	156.901	EPSD	COSMIC;GDSC	145.681	Gain
Other_IKK_TBK1_ST	Q01094	E2F1	Q9UHD2	TBK1	S382	S382L	382	Missense	central	0	yes	150.970	0.000	EPSD	COSMIC	145.681	Loss
Other_IKK_TBK1_ST	Q92985	IRF7	Q9UHD2	TBK1	S388	G382R	382	Missense	distal	-6	no	133.400	147.206	EPSD	COSMIC	145.681	Gain
Other_IKK_TBK1_ST	Q92985	IRF7	Q9UHD2	TBK1	S471	S471N	471	Missense	central	0	yes	179.793	0.000	EPSD;PhosphoSitePlus	COSMIC	145.681	Loss
Other_IKK_TBK1_ST	Q92985	IRF7	Q9UHD2	TBK1	S472	S471N	471	Missense	proximal	-1	no	185.384	186.641	EPSD;PhosphoSitePlus	COSMIC	145.681	Up-regulation
Other_IKK_TBK1_ST	Q92985	IRF7	Q9UHD2	TBK1	S477	S484F	484	Missense	distal	7	no	177.525	177.636	PhosphoSitePlus;EPSD	COSMIC	145.681	Up-regulation
Other_IKK_TBK1_ST	Q92985	IRF7	Q9UHD2	TBK1	S477	S471N	471	Missense	distal	-6	no	177.525	169.105	PhosphoSitePlus;EPSD	COSMIC	145.681	Down-regulation
Other_IKK_TBK1_ST	Q92985	IRF7	Q9UHD2	TBK1	S479	S484F	484	Missense	distal	5	no	186.700	183.119	EPSD;PhosphoSitePlus	COSMIC	145.681	Down-regulation
Other_IKK_TBK1_ST	Q92985	IRF7	Q9UHD2	TBK1	S483	S484F	484	Missense	proximal	1	no	166.191	188.357	EPSD	COSMIC	145.681	Up-regulation
Other_IKK_TBK1_ST	Q92985	IRF7	Q9UHD2	TBK1	S487	S484F	484	Missense	distal	-3	no	149.138	140.186	EPSD	COSMIC	145.681	Loss
Other_IKK_TBK1_ST	Q92985	IRF7	Q9UHD2	TBK1	S487	E493Q	493	Missense	distal	6	no	149.138	150.667	EPSD	COSMIC	145.681	Up-regulation
Other_IKK_TBK1_ST	Q9BRV8	SIKE1	Q9UHD2	TBK1	S59	K66Q	66	Missense	distal	7	no	164.059	164.003	EPSD	COSMIC	145.681	Down-regulation
Other_IKK_TBK1_ST	Q9BRV8	SIKE1	Q9UHD2	TBK1	S59	D57H	57	Missense	proximal	-2	no	164.059	163.132	EPSD	COSMIC	145.681	Down-regulation
Other_IKK_TBK1_ST	Q9BRV8	SIKE1	Q9UHD2	TBK1	S59	Q55E	55	Missense	distal	-4	no	164.059	163.614	EPSD	COSMIC	145.681	Down-regulation
Other_IKK_TBK1_ST	Q9BRV8	SIKE1	Q9UHD2	TBK1	S59	D60N	60	Missense	proximal	1	no	164.059	150.519	EPSD	COSMIC	145.681	Down-regulation
Other_IKK_TBK1_ST	Q9BRV8	SIKE1	Q9UHD2	TBK1	S59	K62Q	62	Missense	distal	3	no	164.059	163.224	EPSD	COSMIC	145.681	Down-regulation
Other_IKK_TBK1_ST	Q9BRV8	SIKE1	Q9UHD2	TBK1	S133	A136V	136	Missense	distal	3	no	177.471	177.935	EPSD;PhosphoSitePlus	COSMIC	145.681	Up-regulation
Other_IKK_TBK1_ST	Q9BRV8	SIKE1	Q9UHD2	TBK1	S133	P126L	126	Missense	distal	-7	no	177.471	178.063	EPSD;PhosphoSitePlus	COSMIC	145.681	Up-regulation
Other_IKK_TBK1_ST	Q9BRV8	SIKE1	Q9UHD2	TBK1	S133	E139D	139	Missense	distal	6	no	177.471	176.043	EPSD;PhosphoSitePlus	COSMIC	145.681	Down-regulation
Other_IKK_TBK1_ST	P31749	AKT1	Q9UHD2	TBK1	T87	R86H	86	Missense	proximal	-1	no	145.011	146.155	EPSD	COSMIC;GDSC;CCLE	145.681	Gain
Other_IKK_TBK1_ST	P31749	AKT1	Q9UHD2	TBK1	T87	I84T	84	Missense	distal	-3	no	145.011	147.800	EPSD	COSMIC	145.681	Gain
Other_IKK_TBK1_ST	P31749	AKT1	Q9UHD2	TBK1	S122	E115K	115	Missense	distal	-7	no	162.113	161.581	EPSD	COSMIC	145.681	Down-regulation
Other_IKK_TBK1_ST	P31749	AKT1	Q9UHD2	TBK1	S122	G123D	123	Missense	proximal	1	no	162.113	164.344	EPSD	COSMIC	145.681	Up-regulation
Other_IKK_TBK1_ST	P31749	AKT1	Q9UHD2	TBK1	S122	D127N	127	Missense	distal	5	no	162.113	157.860	EPSD	COSMIC	145.681	Down-regulation
Other_IKK_TBK1_ST	P31749	AKT1	Q9UHD2	TBK1	S122	E116D	116	Missense	distal	-6	no	162.113	168.724	EPSD	COSMIC	145.681	Up-regulation
Other_IKK_TBK1_ST	P31749	AKT1	Q9UHD2	TBK1	S126	G130R	130	Missense	distal	4	no	143.033	148.324	EPSD	COSMIC	145.681	Gain
Other_IKK_TBK1_ST	P31749	AKT1	Q9UHD2	TBK1	T308	M306T	306	Missense	proximal	-2	no	166.338	166.602	EPSD;PhosphoSitePlus	COSMIC	145.681	Up-regulation
Other_IKK_TBK1_ST	P31749	AKT1	Q9UHD2	TBK1	T308	M306L	306	Missense	proximal	-2	no	166.338	167.064	EPSD;PhosphoSitePlus	COSMIC	145.681	Up-regulation
Other_IKK_TBK1_ST	P31749	AKT1	Q9UHD2	TBK1	T308	M306I	306	Missense	proximal	-2	no	166.338	166.188	EPSD;PhosphoSitePlus	COSMIC	145.681	Down-regulation
Other_IKK_TBK1_ST	P31749	AKT1	Q9UHD2	TBK1	T308	T312I	312	Missense	distal	4	no	166.338	162.664	EPSD;PhosphoSitePlus	COSMIC	145.681	Down-regulation
Other_IKK_TBK1_ST	P31749	AKT1	Q9UHD2	TBK1	T308	G303S	303	Missense	distal	-5	no	166.338	167.093	EPSD;PhosphoSitePlus	COSMIC	145.681	Up-regulation
Other_IKK_TBK1_ST	P31749	AKT1	Q9UHD2	TBK1	S457	E464K	464	Missense	distal	7	no	151.106	151.166	EPSD	COSMIC	145.681	Up-regulation
Other_IKK_TBK1_ST	P31749	AKT1	Q9UHD2	TBK1	S457	P452L	452	Missense	distal	-5	no	151.106	152.204	EPSD	COSMIC	145.681	Up-regulation
Other_IKK_TBK1_ST	P31749	AKT1	Q9UHD2	TBK1	S457	C460S	460	Missense	distal	3	no	151.106	149.278	EPSD	COSMIC	145.681	Down-regulation
Other_IKK_TBK1_ST	P31749	AKT1	Q9UHD2	TBK1	S457	M458I	458	Missense	proximal	1	no	151.106	154.505	EPSD	COSMIC	145.681	Up-regulation
Other_IKK_TBK1_ST	P31749	AKT1	Q9UHD2	TBK1	S473	S477N	477	Missense	distal	4	no	176.752	170.552	PhosphoSitePlus;EPSD	COSMIC	145.681	Down-regulation
Other_IKK_TBK1_ST	P31749	AKT1	Q9UHD2	TBK1	S473	P470L	470	Missense	distal	-3	no	176.752	177.571	PhosphoSitePlus;EPSD	COSMIC	145.681	Up-regulation
Other_IKK_TBK1_ST	P31749	AKT1	Q9UHD2	TBK1	S475	S477N	477	Missense	proximal	2	no	156.921	150.218	EPSD	COSMIC	145.681	Down-regulation
Other_IKK_TBK1_ST	P31749	AKT1	Q9UHD2	TBK1	S475	P470L	470	Missense	distal	-5	no	156.921	158.019	EPSD	COSMIC	145.681	Up-regulation
Other_IKK_TBK1_ST	P31749	AKT1	Q9UHD2	TBK1	S477	P470L	470	Missense	distal	-7	no	145.361	145.953	EPSD	COSMIC	145.681	Gain
Other_IKK_TBK1_ST	P42226	STAT6	Q9UHD2	TBK1	S407	I401M	401	Missense	distal	-6	no	181.141	180.626	PhosphoSitePlus	COSMIC	145.681	Down-regulation
Other_IKK_TBK1_ST	P42226	STAT6	Q9UHD2	TBK1	S407	V411M	411	Missense	distal	4	no	181.141	176.900	PhosphoSitePlus	COSMIC	145.681	Down-regulation
Other_IKK_TBK1_ST	P42226	STAT6	Q9UHD2	TBK1	S407	P400S	400	Missense	distal	-7	no	181.141	181.655	PhosphoSitePlus	COSMIC	145.681	Up-regulation
Other_IKK_TBK1_ST	P42226	STAT6	Q9UHD2	TBK1	S407	V414L	414	Missense	distal	7	no	181.141	181.084	PhosphoSitePlus	COSMIC	145.681	Down-regulation
Other_IKK_TBK1_ST	P42226	STAT6	Q9UHD2	TBK1	S407	V411L	411	Missense	distal	4	no	181.141	175.787	PhosphoSitePlus	COSMIC	145.681	Down-regulation
Other_IKK_TBK1_ST	P42226	STAT6	Q9UHD2	TBK1	S756	L761F	761	Missense	distal	5	no	146.709	144.828	EPSD	COSMIC;GDSC;CCLE	145.681	Loss
Other_IKK_TBK1_ST	P42226	STAT6	Q9UHD2	TBK1	S756	A753V	753	Missense	distal	-3	no	146.709	147.602	EPSD	COSMIC	145.681	Up-regulation
Other_IKK_TBK1_ST	P42226	STAT6	Q9UHD2	TBK1	S763	L761F	761	Missense	proximal	-2	no	165.908	164.693	EPSD	COSMIC;GDSC;CCLE	145.681	Down-regulation
Other_IKK_TBK1_ST	P42226	STAT6	Q9UHD2	TBK1	S827	Q831H	831	Missense	distal	4	no	145.999	144.453	EPSD	COSMIC	145.681	Loss
Other_IKK_TBK1_ST	P42226	STAT6	Q9UHD2	TBK1	S827	L824V	824	Missense	distal	-3	no	145.999	145.451	EPSD	COSMIC;GDSC	145.681	Loss
Other_IKK_TBK1_ST	Q9UHD2	TBK1	Q9UHD2	TBK1	T78	T79P	79	Missense	proximal	1	no	112.762	152.986	EPSD	COSMIC	145.681	Gain
Other_IKK_TBK1_ST	Q9UHD2	TBK1	Q9UHD2	TBK1	T79	T79P	79	Missense	central	0	yes	161.760	0.000	EPSD	COSMIC	145.681	Loss
Other_IKK_TBK1_ST	Q9UHD2	TBK1	Q9UHD2	TBK1	T79	R80T	80	Missense	proximal	1	no	161.760	121.660	EPSD	COSMIC	145.681	Loss
Other_IKK_TBK1_ST	Q9UHD2	TBK1	Q9UHD2	TBK1	T79	V83I	83	Missense	distal	4	no	161.760	153.426	EPSD	COSMIC	145.681	Down-regulation
Other_IKK_TBK1_ST	Q9UHD2	TBK1	Q9UHD2	TBK1	S172	S172Y	172	Missense	central	0	yes	192.036	0.000	PhosphoSitePlus	COSMIC	145.681	Loss
Other_IKK_TBK1_ST	Q9UHD2	TBK1	Q9UHD2	TBK1	T176	S172Y	172	Missense	distal	-4	no	158.077	156.597	EPSD	COSMIC	145.681	Down-regulation
Other_IKK_TBK1_ST	Q9UHD2	TBK1	Q9UHD2	TBK1	T176	D183G	183	Missense	distal	7	no	158.077	158.127	EPSD	COSMIC	145.681	Up-regulation
Other_IKK_TBK1_ST	Q9UHD2	TBK1	Q9UHD2	TBK1	S509	S510I	510	Missense	proximal	1	no	158.064	171.441	EPSD	COSMIC;GDSC;CCLE	145.681	Up-regulation
Other_IKK_TBK1_ST	Q9UHD2	TBK1	Q9UHD2	TBK1	S509	K504E	504	Missense	distal	-5	no	158.064	158.036	EPSD	COSMIC	145.681	Down-regulation
Other_IKK_TBK1_ST	Q9UHD2	TBK1	Q9UHD2	TBK1	S510	S510I	510	Missense	central	0	yes	161.396	0.000	EPSD	COSMIC;GDSC;CCLE	145.681	Loss
Other_IKK_TBK1_ST	Q9UHD2	TBK1	Q9UHD2	TBK1	S510	K504E	504	Missense	distal	-6	no	161.396	164.173	EPSD	COSMIC	145.681	Up-regulation
Other_IKK_TBK1_ST	Q9UHD2	TBK1	Q9UHD2	TBK1	S527	D534N	534	Missense	distal	7	no	157.770	157.850	EPSD	COSMIC	145.681	Up-regulation
Other_IKK_TBK1_ST	Q9UHD2	TBK1	Q9UHD2	TBK1	S716	I710N	710	Missense	distal	-6	no	166.161	170.460	EPSD	COSMIC	145.681	Up-regulation
Other_IKK_TBK1_ST	Q13568	IRF5	Q9UHD2	TBK1	S156	V163M	163	Missense	distal	7	no	160.190	160.139	EPSD	COSMIC	145.681	Down-regulation
Other_IKK_TBK1_ST	Q13568	IRF5	Q9UHD2	TBK1	S158	V163M	163	Missense	distal	5	no	182.527	181.811	EPSD;PhosphoSitePlus	COSMIC	145.681	Down-regulation
Other_IKK_TBK1_ST	Q13568	IRF5	Q9UHD2	TBK1	S293	L288F	288	Missense	distal	-5	no	177.832	176.486	PhosphoSitePlus;EPSD	COSMIC	145.681	Down-regulation
Other_IKK_TBK1_ST	Q13568	IRF5	Q9UHD2	TBK1	S293	P300S	300	Missense	distal	7	no	177.832	177.797	PhosphoSitePlus;EPSD	COSMIC	145.681	Down-regulation
Other_IKK_TBK1_ST	Q13568	IRF5	Q9UHD2	TBK1	S293	P300L	300	Missense	distal	7	no	177.832	177.791	PhosphoSitePlus;EPSD	COSMIC	145.681	Down-regulation
Other_IKK_TBK1_ST	Q13568	IRF5	Q9UHD2	TBK1	S293	E295K	295	Missense	proximal	2	no	177.832	175.938	PhosphoSitePlus;EPSD	COSMIC	145.681	Down-regulation
Other_IKK_TBK1_ST	Q13568	IRF5	Q9UHD2	TBK1	S440	R442Q	442	Missense	proximal	2	no	156.202	156.260	EPSD	COSMIC	145.681	Up-regulation
Other_IKK_TBK1_ST	Q13568	IRF5	Q9UHD2	TBK1	S446	R442Q	442	Missense	distal	-4	no	159.504	160.516	EPSD	COSMIC	145.681	Up-regulation
Other_IKK_TBK1_ST	Q13568	IRF5	Q9UHD2	TBK1	S467	Q468R	468	Missense	proximal	1	no	131.256	147.608	EPSD	COSMIC	145.681	Gain
Other_IKK_TBK1_ST	Q8IUC6	TICAM1	Q9UHD2	TBK1	S60	E62K	62	Missense	proximal	2	no	158.797	156.904	EPSD	COSMIC	145.681	Down-regulation
Other_IKK_TBK1_ST	Q8IUC6	TICAM1	Q9UHD2	TBK1	S60	R58M	58	Missense	proximal	-2	no	158.797	158.799	EPSD	COSMIC;GDSC;CCLE	145.681	Up-regulation
Other_IKK_TBK1_ST	Q8IUC6	TICAM1	Q9UHD2	TBK1	S223	S223I	223	Missense	central	0	yes	159.415	0.000	EPSD	COSMIC	145.681	Loss
Other_IKK_TBK1_ST	Q8IUC6	TICAM1	Q9UHD2	TBK1	S223	L218P	218	Missense	distal	-5	no	159.415	158.317	EPSD	COSMIC	145.681	Down-regulation
Other_IKK_TBK1_ST	Q8IUC6	TICAM1	Q9UHD2	TBK1	S223	S219I	219	Missense	distal	-4	no	159.415	158.252	EPSD	COSMIC	145.681	Down-regulation
Other_IKK_TBK1_ST	Q8IUC6	TICAM1	Q9UHD2	TBK1	S500	Q498K	498	Missense	proximal	-2	no	158.144	156.949	EPSD	COSMIC	145.681	Down-regulation
Other_IKK_TBK1_ST	Q8IUC6	TICAM1	Q9UHD2	TBK1	S500	T503M	503	Missense	distal	3	no	158.144	156.827	EPSD	COSMIC	145.681	Down-regulation
Other_IKK_TBK1_ST	Q04206	RELA	Q9UHD2	TBK1	S45	E39Q	39	Missense	distal	-6	no	150.604	163.106	EPSD	COSMIC	145.681	Up-regulation
Other_IKK_TBK1_ST	Q04206	RELA	Q9UHD2	TBK1	S261	R267C	267	Missense	distal	6	no	152.743	147.381	EPSD	COSMIC	145.681	Down-regulation
Other_IKK_TBK1_ST	Q04206	RELA	Q9UHD2	TBK1	S261	P256H	256	Missense	distal	-5	no	152.743	152.192	EPSD	COSMIC	145.681	Down-regulation
Other_IKK_TBK1_ST	Q04206	RELA	Q9UHD2	TBK1	S319	P326S	326	Missense	distal	7	no	158.507	158.472	EPSD	COSMIC	145.681	Down-regulation
Other_IKK_TBK1_ST	Q04206	RELA	Q9UHD2	TBK1	S319	M313I	313	Missense	distal	-6	no	158.507	159.022	EPSD	COSMIC	145.681	Up-regulation
Other_IKK_TBK1_ST	Q04206	RELA	Q9UHD2	TBK1	S319	R325W	325	Missense	distal	6	no	158.507	147.670	EPSD	COSMIC	145.681	Down-regulation
Other_IKK_TBK1_ST	Q04206	RELA	Q9UHD2	TBK1	S319	K314N	314	Missense	distal	-5	no	158.507	158.043	EPSD	COSMIC	145.681	Down-regulation
Other_IKK_TBK1_ST	Q04206	RELA	Q9UHD2	TBK1	S319	P324S	324	Missense	distal	5	no	158.507	159.178	EPSD	COSMIC	145.681	Up-regulation
Other_IKK_TBK1_ST	Q04206	RELA	Q9UHD2	TBK1	T322	P326S	326	Missense	distal	4	no	144.904	151.126	EPSD	COSMIC	145.681	Gain
Other_IKK_TBK1_ST	Q04206	RELA	Q9UHD2	TBK1	T322	R325W	325	Missense	distal	3	no	144.904	147.008	EPSD	COSMIC	145.681	Gain
Other_IKK_TBK1_ST	Q04206	RELA	Q9UHD2	TBK1	T322	P324S	324	Missense	proximal	2	no	144.904	151.064	EPSD	COSMIC	145.681	Gain
Other_IKK_TBK1_ST	Q04206	RELA	Q9UHD2	TBK1	S337	P334S	334	Missense	distal	-3	no	142.364	146.628	EPSD	COSMIC	145.681	Gain
Other_IKK_TBK1_ST	Q04206	RELA	Q9UHD2	TBK1	S340	P334S	334	Missense	distal	-6	no	137.356	151.804	EPSD	COSMIC	145.681	Gain
Other_IKK_TBK1_ST	Q04206	RELA	Q9UHD2	TBK1	T435	L440M	440	Missense	distal	5	no	145.704	146.825	EPSD	COSMIC	145.681	Up-regulation
Other_IKK_TBK1_ST	Q04206	RELA	Q9UHD2	TBK1	T435	T429P	429	Missense	distal	-6	no	145.704	139.317	EPSD	COSMIC	145.681	Loss
Other_IKK_TBK1_ST	Q04206	RELA	Q9UHD2	TBK1	S536	F534L	534	Missense	proximal	-2	no	167.526	168.741	PhosphoSitePlus	COSMIC	145.681	Up-regulation
Other_IKK_TBK1_ST	Q7Z434	MAVS	Q9UHD2	TBK1	S94	R98W	98	Missense	distal	4	no	165.735	154.514	EPSD	COSMIC	145.681	Down-regulation
Other_IKK_TBK1_ST	Q7Z434	MAVS	Q9UHD2	TBK1	S94	S90C	90	Missense	distal	-4	no	165.735	164.577	EPSD	COSMIC	145.681	Down-regulation
Other_IKK_TBK1_ST	Q7Z434	MAVS	Q9UHD2	TBK1	S94	S100L	100	Missense	distal	6	no	165.735	163.322	EPSD	COSMIC	145.681	Down-regulation
Other_IKK_TBK1_ST	Q7Z434	MAVS	Q9UHD2	TBK1	S100	R102H	102	Missense	proximal	2	no	149.638	148.047	EPSD	COSMIC;GDSC;CCLE	145.681	Down-regulation
Other_IKK_TBK1_ST	Q7Z434	MAVS	Q9UHD2	TBK1	S100	P103S	103	Missense	distal	3	no	149.638	147.987	EPSD	COSMIC	145.681	Down-regulation
Other_IKK_TBK1_ST	Q7Z434	MAVS	Q9UHD2	TBK1	S100	R98W	98	Missense	proximal	-2	no	149.638	146.702	EPSD	COSMIC	145.681	Down-regulation
Other_IKK_TBK1_ST	Q7Z434	MAVS	Q9UHD2	TBK1	S100	S100L	100	Missense	central	0	yes	149.638	0.000	EPSD	COSMIC	145.681	Loss
Other_IKK_TBK1_ST	Q7Z434	MAVS	Q9UHD2	TBK1	S100	P104L	104	Missense	distal	4	no	149.638	152.281	EPSD	COSMIC	145.681	Up-regulation
Other_IKK_TBK1_ST	Q7Z434	MAVS	Q9UHD2	TBK1	S111	P104L	104	Missense	distal	-7	no	190.929	191.521	EPSD	COSMIC	145.681	Up-regulation
Other_IKK_TBK1_ST	Q7Z434	MAVS	Q9UHD2	TBK1	S238	G242V	242	Missense	distal	4	no	137.812	149.002	EPSD	COSMIC	145.681	Gain
Other_IKK_TBK1_ST	Q7Z434	MAVS	Q9UHD2	TBK1	S246	V247F	247	Missense	proximal	1	no	125.003	155.728	EPSD	COSMIC	145.681	Gain
Other_IKK_TBK1_ST	Q7Z434	MAVS	Q9UHD2	TBK1	T250	V247F	247	Missense	distal	-3	no	154.502	149.543	EPSD	COSMIC	145.681	Down-regulation
Other_IKK_TBK1_ST	Q7Z434	MAVS	Q9UHD2	TBK1	S253	V247F	247	Missense	distal	-6	no	149.579	146.424	EPSD	COSMIC	145.681	Down-regulation
Other_IKK_TBK1_ST	Q7Z434	MAVS	Q9UHD2	TBK1	S275	G269D	269	Missense	distal	-6	no	135.816	149.879	EPSD	COSMIC	145.681	Gain
Other_IKK_TBK1_ST	Q7Z434	MAVS	Q9UHD2	TBK1	S361	K362Q	362	Missense	proximal	1	no	152.057	161.953	EPSD	COSMIC	145.681	Up-regulation
Other_IKK_TBK1_ST	Q7Z434	MAVS	Q9UHD2	TBK1	S361	A356G	356	Missense	distal	-5	no	152.057	151.769	EPSD	COSMIC	145.681	Down-regulation
Other_IKK_TBK1_ST	Q7Z434	MAVS	Q9UHD2	TBK1	S361	G357D	357	Missense	distal	-4	no	152.057	152.960	EPSD	COSMIC	145.681	Up-regulation
Other_IKK_TBK1_ST	Q7Z434	MAVS	Q9UHD2	TBK1	S361	R355H	355	Missense	distal	-6	no	152.057	150.521	EPSD	COSMIC;GDSC;CCLE	145.681	Down-regulation
Other_IKK_TBK1_ST	Q7Z434	MAVS	Q9UHD2	TBK1	S361	M367I	367	Missense	distal	6	no	152.057	146.818	EPSD	COSMIC	145.681	Down-regulation
Other_IKK_TBK1_ST	Q7Z434	MAVS	Q9UHD2	TBK1	T365	K362Q	362	Missense	distal	-3	no	141.243	148.324	EPSD	COSMIC	145.681	Gain
Other_IKK_TBK1_ST	Q7Z434	MAVS	Q9UHD2	TBK1	S366	K362Q	362	Missense	distal	-4	no	157.086	158.322	EPSD	COSMIC	145.681	Up-regulation
Other_IKK_TBK1_ST	Q7Z434	MAVS	Q9UHD2	TBK1	S366	M367I	367	Missense	proximal	1	no	157.086	160.485	EPSD	COSMIC	145.681	Up-regulation
Other_IKK_TBK1_ST	Q7Z434	MAVS	Q9UHD2	TBK1	S408	E410D	410	Missense	proximal	2	no	157.020	157.819	EPSD	COSMIC	145.681	Up-regulation
Other_IKK_TBK1_ST	Q7Z434	MAVS	Q9UHD2	TBK1	S408	S401T	401	Missense	distal	-7	no	157.020	157.483	EPSD	COSMIC	145.681	Up-regulation
Other_IKK_TBK1_ST	P30086	PEBP1	Q9UHD2	TBK1	S52	R49T	49	Missense	distal	-3	no	146.491	149.486	EPSD	COSMIC;GDSC;CCLE	145.681	Up-regulation
Other_IKK_TBK1_ST	P30086	PEBP1	Q9UHD2	TBK1	S52	D59E	59	Missense	distal	7	no	146.491	146.515	EPSD	COSMIC	145.681	Up-regulation
Other_IKK_TBK1_ST	P30086	PEBP1	Q9UHD2	TBK1	S60	K62R	62	Missense	proximal	2	no	153.647	153.641	EPSD	COSMIC	145.681	Down-regulation
Other_IKK_TBK1_ST	P30086	PEBP1	Q9UHD2	TBK1	S60	D59E	59	Missense	proximal	-1	no	153.647	153.991	EPSD	COSMIC	145.681	Up-regulation
Other_IKK_TBK1_ST	P30086	PEBP1	Q9UHD2	TBK1	S98	D105N	105	Missense	distal	7	no	145.978	146.059	EPSD	COSMIC	145.681	Up-regulation
Other_IKK_TBK1_ST	P30086	PEBP1	Q9UHD2	TBK1	S98	D105A	105	Missense	distal	7	no	145.978	146.001	EPSD	COSMIC	145.681	Up-regulation
Other_IKK_TBK1_ST	P30086	PEBP1	Q9UHD2	TBK1	S99	D105N	105	Missense	distal	6	no	158.633	160.949	EPSD	COSMIC	145.681	Up-regulation
Other_IKK_TBK1_ST	P30086	PEBP1	Q9UHD2	TBK1	S99	D105A	105	Missense	distal	6	no	158.633	163.755	EPSD	COSMIC	145.681	Up-regulation
Other_IKK_TBK1_ST	P30086	PEBP1	Q9UHD2	TBK1	T101	D105N	105	Missense	distal	4	no	152.009	149.676	EPSD	COSMIC	145.681	Down-regulation
Other_IKK_TBK1_ST	P30086	PEBP1	Q9UHD2	TBK1	T101	D105A	105	Missense	distal	4	no	152.009	156.881	EPSD	COSMIC	145.681	Up-regulation
Other_IKK_TBK1_ST	P30086	PEBP1	Q9UHD2	TBK1	S109	D105N	105	Missense	distal	-4	no	177.206	176.330	PhosphoSitePlus	COSMIC	145.681	Down-regulation
Other_IKK_TBK1_ST	P30086	PEBP1	Q9UHD2	TBK1	S109	G110R	110	Missense	proximal	1	no	177.206	186.745	PhosphoSitePlus	COSMIC	145.681	Up-regulation
Other_IKK_TBK1_ST	P30086	PEBP1	Q9UHD2	TBK1	S109	D105A	105	Missense	distal	-4	no	177.206	177.416	PhosphoSitePlus	COSMIC	145.681	Up-regulation
Other_IKK_TBK1_ST	P30086	PEBP1	Q9UHD2	TBK1	S153	R155G	155	Missense	proximal	2	no	158.653	155.907	EPSD	COSMIC	145.681	Down-regulation
Other_IKK_TBK1_ST	P03372	ESR1	Q9UHD2	TBK1	S104	F97L	97	Missense	distal	-7	no	154.752	156.768	EPSD	COSMIC	145.681	Up-regulation
Other_IKK_TBK1_ST	P03372	ESR1	Q9UHD2	TBK1	S104	M109T	109	Missense	distal	5	no	154.752	154.373	EPSD	COSMIC	145.681	Down-regulation
Other_IKK_TBK1_ST	P03372	ESR1	Q9UHD2	TBK1	S305	K303R	303	Missense	proximal	-2	no	183.655	184.254	PhosphoSitePlus	COSMIC	145.681	Up-regulation
Other_IKK_TBK1_ST	P03372	ESR1	Q9UHD2	TBK1	S305	K299R	299	Missense	distal	-6	no	183.655	192.787	PhosphoSitePlus	COSMIC	145.681	Up-regulation
Other_IKK_TBK1_ST	P03372	ESR1	Q9UHD2	TBK1	S305	N304S	304	Missense	proximal	-1	no	183.655	182.398	PhosphoSitePlus	COSMIC	145.681	Down-regulation
Other_IKK_TBK1_ST	P03372	ESR1	Q9UHD2	TBK1	S305	R300C	300	Missense	distal	-5	no	183.655	182.597	PhosphoSitePlus	COSMIC;CCLE	145.681	Down-regulation
Other_IKK_TBK1_ST	P03372	ESR1	Q9UHD2	TBK1	S305	A307P	307	Missense	proximal	2	no	183.655	179.465	PhosphoSitePlus	COSMIC	145.681	Down-regulation
Other_IKK_TBK1_ST	P03372	ESR1	Q9UHD2	TBK1	S305	N304H	304	Missense	proximal	-1	no	183.655	183.772	PhosphoSitePlus	COSMIC	145.681	Up-regulation
Other_IKK_TBK1_ST	P03372	ESR1	Q9UHD2	TBK1	S341	S338G	338	Missense	distal	-3	no	174.879	173.006	EPSD	COSMIC	145.681	Down-regulation
Other_IKK_TBK1_ST	P03372	ESR1	Q9UHD2	TBK1	S341	S338R	338	Missense	distal	-3	no	174.879	167.790	EPSD	COSMIC	145.681	Down-regulation
Other_IKK_TBK1_ST	P03372	ESR1	Q9UHD2	TBK1	S341	T347I	347	Missense	distal	6	no	174.879	175.638	EPSD	COSMIC	145.681	Up-regulation
Other_IKK_TBK1_ST	P03372	ESR1	Q9UHD2	TBK1	S341	M343L	343	Missense	proximal	2	no	174.879	173.990	EPSD	COSMIC	145.681	Down-regulation
Other_IKK_TBK1_ST	P03372	ESR1	Q9UHD2	TBK1	S554	G557R	557	Missense	distal	3	no	155.372	154.874	EPSD	COSMIC	145.681	Down-regulation
Other_IKK_TBK1_ST	P03372	ESR1	Q9UHD2	TBK1	S554	H550Y	550	Missense	distal	-4	no	155.372	154.966	EPSD	COSMIC	145.681	Down-regulation
Other_IKK_TBK1_ST	P03372	ESR1	Q9UHD2	TBK1	S554	L549P	549	Missense	distal	-5	no	155.372	154.273	EPSD	COSMIC	145.681	Down-regulation
Other_IKK_TBK1_ST	P03372	ESR1	Q9UHD2	TBK1	S554	V560M	560	Missense	distal	6	no	155.372	154.010	EPSD	COSMIC	145.681	Down-regulation
Other_IKK_TBK1_ST	P03372	ESR1	Q9UHD2	TBK1	S559	V560M	560	Missense	proximal	1	no	128.805	147.342	EPSD	COSMIC	145.681	Gain
Other_IKK_TBK1_ST	P03372	ESR1	Q9UHD2	TBK1	S573	S578Y	578	Missense	distal	5	no	146.561	143.373	EPSD	COSMIC	145.681	Loss
Other_IKK_TBK1_ST	P03372	ESR1	Q9UHD2	TBK1	S578	T585S	585	Missense	distal	7	no	159.592	159.573	EPSD	COSMIC	145.681	Down-regulation
Other_IKK_TBK1_ST	P03372	ESR1	Q9UHD2	TBK1	S578	S578Y	578	Missense	central	0	yes	159.592	0.000	EPSD	COSMIC	145.681	Loss
TK_Tie_TEK_Y	Q02763	TEK	Q02763	TEK	Y860	R867M	867	Missense	distal	7	no	2.860	2.856	EPSD	COSMIC	0.993	Down-regulation
TK_Tie_TEK_Y	Q02763	TEK	Q02763	TEK	Y860	I854F	854	Missense	distal	-6	no	2.860	2.709	EPSD	COSMIC	0.993	Down-regulation
TK_Tie_TEK_Y	Q02763	TEK	Q02763	TEK	Y992	G988S	988	Missense	distal	-4	no	3.019	2.915	PhosphoSitePlus;EPSD	COSMIC	0.993	Down-regulation
TK_Tie_TEK_Y	Q02763	TEK	Q02763	TEK	Y992	E990K	990	Missense	proximal	-2	no	3.019	3.061	PhosphoSitePlus;EPSD	COSMIC	0.993	Up-regulation
TK_Tie_TEK_Y	Q02763	TEK	Q02763	TEK	Y992	R999S	999	Missense	distal	7	no	3.019	3.010	PhosphoSitePlus;EPSD	COSMIC	0.993	Down-regulation
TK_Tie_TEK_Y	Q02763	TEK	Q02763	TEK	Y992	G988V	988	Missense	distal	-4	no	3.019	2.959	PhosphoSitePlus;EPSD	COSMIC	0.993	Down-regulation
TK_Tie_TEK_Y	Q02763	TEK	Q02763	TEK	Y1102	K1100Q	1100	Missense	proximal	-2	no	2.672	2.606	EPSD	COSMIC	0.993	Down-regulation
TK_Tie_TEK_Y	Q02763	TEK	Q02763	TEK	Y1108	F1111C	1111	Missense	distal	3	no	2.631	2.639	EPSD;PhosphoSitePlus	COSMIC;GDSC;CCLE	0.993	Up-regulation
TK_Tie_TEK_Y	Q02763	TEK	Q02763	TEK	Y1108	A1114E	1114	Missense	distal	6	no	2.631	2.610	EPSD;PhosphoSitePlus	COSMIC	0.993	Down-regulation
TK_Tie_TEK_Y	Q02763	TEK	Q02763	TEK	Y1108	E1109D	1109	Missense	proximal	1	no	2.631	2.528	EPSD;PhosphoSitePlus	COSMIC	0.993	Down-regulation
TK_Tie_TEK_Y	Q02763	TEK	Q02763	TEK	Y1113	F1111C	1111	Missense	proximal	-2	no	2.428	2.397	EPSD	COSMIC;GDSC;CCLE	0.993	Down-regulation
TK_Tie_TEK_Y	Q02763	TEK	Q02763	TEK	Y1113	A1114E	1114	Missense	proximal	1	no	2.428	2.419	EPSD	COSMIC	0.993	Down-regulation
TK_Tie_TEK_Y	Q02763	TEK	Q02763	TEK	Y1113	D1117H	1117	Missense	distal	4	no	2.428	2.134	EPSD	COSMIC	0.993	Down-regulation
TK_Tie_TEK_Y	Q02763	TEK	Q02763	TEK	Y1113	E1109D	1109	Missense	distal	-4	no	2.428	2.417	EPSD	COSMIC	0.993	Down-regulation
CAMK_PKD_PRKD3_ST	Q9UQL6	HDAC5	O94806	PRKD3	S7	E6K	6	Missense	proximal	-1	no	2.665	2.834	EPSD	COSMIC	1.136	Up-regulation
CAMK_PKD_PRKD3_ST	Q9UQL6	HDAC5	O94806	PRKD3	S7	R13W	13	Missense	distal	6	no	2.665	2.648	EPSD	COSMIC	1.136	Down-regulation
CAMK_PKD_PRKD3_ST	Q9UQL6	HDAC5	O94806	PRKD3	S7	G12R	12	Missense	distal	5	no	2.665	2.667	EPSD	COSMIC	1.136	Up-regulation
CAMK_PKD_PRKD3_ST	Q9UQL6	HDAC5	O94806	PRKD3	T199	G202S	202	Missense	distal	3	no	2.172	2.198	EPSD	COSMIC	1.136	Up-regulation
CAMK_PKD_PRKD3_ST	Q9UQL6	HDAC5	O94806	PRKD3	T199	P198T	198	Missense	proximal	-1	no	2.172	2.449	EPSD	COSMIC	1.136	Up-regulation
CAMK_PKD_PRKD3_ST	Q9UQL6	HDAC5	O94806	PRKD3	T199	S193L	193	Missense	distal	-6	no	2.172	2.064	EPSD	COSMIC	1.136	Down-regulation
CAMK_PKD_PRKD3_ST	Q9UQL6	HDAC5	O94806	PRKD3	T199	K196N	196	Missense	distal	-3	no	2.172	2.200	EPSD	COSMIC	1.136	Up-regulation
CAMK_PKD_PRKD3_ST	Q9UQL6	HDAC5	O94806	PRKD3	S229	G230A	230	Missense	proximal	1	no	1.147	1.179	EPSD	COSMIC	1.136	Up-regulation
CAMK_PKD_PRKD3_ST	Q9UQL6	HDAC5	O94806	PRKD3	S229	P232L	232	Missense	distal	3	no	1.147	1.100	EPSD	COSMIC	1.136	Loss
CAMK_PKD_PRKD3_ST	Q9UQL6	HDAC5	O94806	PRKD3	S229	S224R	224	Missense	distal	-5	no	1.147	1.333	EPSD	COSMIC	1.136	Up-regulation
CAMK_PKD_PRKD3_ST	Q9UQL6	HDAC5	O94806	PRKD3	S229	G230R	230	Missense	proximal	1	no	1.147	1.113	EPSD	COSMIC;CCLE	1.136	Loss
CAMK_PKD_PRKD3_ST	Q9UQL6	HDAC5	O94806	PRKD3	S229	G230D	230	Missense	proximal	1	no	1.147	1.139	EPSD	COSMIC;CCLE	1.136	Down-regulation
CAMK_PKD_PRKD3_ST	Q9UQL6	HDAC5	O94806	PRKD3	S229	P236S	236	Missense	distal	7	no	1.147	1.159	EPSD	COSMIC	1.136	Up-regulation
CAMK_PKD_PRKD3_ST	Q9UQL6	HDAC5	O94806	PRKD3	S229	G230S	230	Missense	proximal	1	no	1.147	1.178	EPSD	COSMIC	1.136	Up-regulation
CAMK_PKD_PRKD3_ST	Q9UQL6	HDAC5	O94806	PRKD3	S229	P232T	232	Missense	distal	3	no	1.147	1.040	EPSD	COSMIC	1.136	Loss
CAMK_PKD_PRKD3_ST	Q9UQL6	HDAC5	O94806	PRKD3	S469	R476H	476	Missense	distal	7	no	1.455	1.470	EPSD	COSMIC	1.136	Up-regulation
CAMK_PKD_PRKD3_ST	Q9UQL6	HDAC5	O94806	PRKD3	S469	T473M	473	Missense	distal	4	no	1.455	1.446	EPSD	COSMIC	1.136	Down-regulation
CAMK_PKD_PRKD3_ST	Q9UQL6	HDAC5	O94806	PRKD3	S469	G474C	474	Missense	distal	5	no	1.455	1.453	EPSD	COSMIC	1.136	Down-regulation
CAMK_PKD_PRKD3_ST	Q9UQL6	HDAC5	O94806	PRKD3	S469	R476C	476	Missense	distal	7	no	1.455	1.458	EPSD	COSMIC	1.136	Up-regulation
CAMK_PKD_PRKD3_ST	Q9UQL6	HDAC5	O94806	PRKD3	S469	H466N	466	Missense	distal	-3	no	1.455	1.473	EPSD	COSMIC	1.136	Up-regulation
CAMK_PKD_PRKD3_ST	Q9UQL6	HDAC5	O94806	PRKD3	S498	R491W	491	Missense	distal	-7	no	5.901	5.808	PhosphoSitePlus	COSMIC	1.136	Down-regulation
CAMK_PKD_PRKD3_ST	Q9UQL6	HDAC5	O94806	PRKD3	S1108	E1106K	1106	Missense	proximal	-2	no	1.221	1.245	EPSD	COSMIC	1.136	Up-regulation
CAMK_PKD_PRKD3_ST	Q9UQL6	HDAC5	O94806	PRKD3	S1108	A1104T	1104	Missense	distal	-4	no	1.221	1.244	EPSD	COSMIC;CCLE	1.136	Up-regulation
CAMK_PKD_PRKD3_ST	Q15139	PRKD1	O94806	PRKD3	S239	K245N	245	Missense	distal	6	no	2.155	2.117	EPSD	COSMIC	1.136	Down-regulation
CAMK_PKD_PRKD3_ST	Q15139	PRKD1	O94806	PRKD3	S239	S239L	239	Missense	central	0	yes	2.155	0.000	EPSD	COSMIC	1.136	Loss
CAMK_PKD_PRKD3_ST	Q15139	PRKD1	O94806	PRKD3	S412	S412F	412	Missense	central	0	yes	2.536	0.000	EPSD	COSMIC	1.136	Loss
CAMK_PKD_PRKD3_ST	Q15139	PRKD1	O94806	PRKD3	S412	Q411H	411	Missense	proximal	-1	no	2.536	2.406	EPSD	COSMIC	1.136	Down-regulation
CAMK_PKD_PRKD3_ST	Q15139	PRKD1	O94806	PRKD3	S412	V413D	413	Missense	proximal	1	no	2.536	2.524	EPSD	COSMIC	1.136	Down-regulation
CAMK_PKD_PRKD3_ST	Q15139	PRKD1	O94806	PRKD3	S412	Q411L	411	Missense	proximal	-1	no	2.536	2.329	EPSD	COSMIC	1.136	Down-regulation
CAMK_PKD_PRKD3_ST	Q15139	PRKD1	O94806	PRKD3	S549	T552I	552	Missense	distal	3	no	2.374	2.387	EPSD	COSMIC	1.136	Up-regulation
CAMK_PKD_PRKD3_ST	Q15139	PRKD1	O94806	PRKD3	S549	G553E	553	Missense	distal	4	no	2.374	2.368	EPSD	COSMIC	1.136	Down-regulation
CAMK_PKD_PRKD3_ST	Q15139	PRKD1	O94806	PRKD3	S549	P545H	545	Missense	distal	-4	no	2.374	2.390	EPSD	COSMIC	1.136	Up-regulation
CAMK_PKD_PRKD3_ST	Q15139	PRKD1	O94806	PRKD3	S549	P542R	542	Missense	distal	-7	no	2.374	2.618	EPSD	COSMIC	1.136	Up-regulation
CAMK_PKD_PRKD3_ST	Q15139	PRKD1	O94806	PRKD3	S549	P545S	545	Missense	distal	-4	no	2.374	2.375	EPSD	COSMIC	1.136	Up-regulation
CAMK_PKD_PRKD3_ST	Q15139	PRKD1	O94806	PRKD3	S738	G735V	735	Missense	distal	-3	no	5.753	5.789	PhosphoSitePlus;EPSD	COSMIC	1.136	Up-regulation
CAMK_PKD_PRKD3_ST	Q15139	PRKD1	O94806	PRKD3	S738	V743L	743	Missense	distal	5	no	5.753	5.751	PhosphoSitePlus;EPSD	COSMIC	1.136	Down-regulation
CAMK_PKD_PRKD3_ST	Q15139	PRKD1	O94806	PRKD3	S738	A731D	731	Missense	distal	-7	no	5.753	5.447	PhosphoSitePlus;EPSD	COSMIC	1.136	Down-regulation
CAMK_PKD_PRKD3_ST	Q15139	PRKD1	O94806	PRKD3	S742	A748T	748	Missense	distal	6	no	6.201	6.096	EPSD;PhosphoSitePlus	COSMIC	1.136	Down-regulation
CAMK_PKD_PRKD3_ST	Q15139	PRKD1	O94806	PRKD3	S742	G735V	735	Missense	distal	-7	no	6.201	6.029	EPSD;PhosphoSitePlus	COSMIC	1.136	Down-regulation
CAMK_PKD_PRKD3_ST	Q15139	PRKD1	O94806	PRKD3	S742	V743L	743	Missense	proximal	1	no	6.201	6.204	EPSD;PhosphoSitePlus	COSMIC	1.136	Up-regulation
CAMK_PKD_PRKD3_ST	Q15139	PRKD1	O94806	PRKD3	S742	T746I	746	Missense	distal	4	no	6.201	6.192	EPSD;PhosphoSitePlus	COSMIC	1.136	Down-regulation
CAMK_PKD_PRKD3_ST	Q9Y2X7	GIT1	O94806	PRKD3	S254	E259D	259	Missense	distal	5	no	3.124	3.125	EPSD	COSMIC	1.136	Up-regulation
CAMK_PKD_PRKD3_ST	Q9Y2X7	GIT1	O94806	PRKD3	T307	A311V	311	Missense	distal	4	no	1.729	1.739	EPSD	COSMIC	1.136	Up-regulation
CAMK_PKD_PRKD3_ST	Q9Y2X7	GIT1	O94806	PRKD3	S362	D365V	365	Missense	distal	3	no	1.686	1.699	EPSD	COSMIC	1.136	Up-regulation
CAMK_PKD_PRKD3_ST	Q9Y2X7	GIT1	O94806	PRKD3	T364	D365V	365	Missense	proximal	1	no	1.154	1.166	EPSD	COSMIC	1.136	Up-regulation
CAMK_PKD_PRKD3_ST	Q9Y2X7	GIT1	O94806	PRKD3	S449	S449G	449	Missense	central	0	yes	1.952	0.000	EPSD	COSMIC	1.136	Loss
CAMK_PKD_PRKD3_ST	Q9Y2X7	GIT1	O94806	PRKD3	S449	S449I	449	Missense	central	0	yes	1.952	0.000	EPSD	COSMIC	1.136	Loss
CAMK_PKD_PRKD3_ST	Q9Y2X7	GIT1	O94806	PRKD3	S563	A562V	562	Missense	proximal	-1	no	1.236	1.135	EPSD	COSMIC	1.136	Loss
CAMK_PKD_PRKD3_ST	Q9Y2X7	GIT1	O94806	PRKD3	S563	F567L	567	Missense	distal	4	no	1.236	1.233	EPSD	COSMIC	1.136	Down-regulation
CAMK_PKD_PRKD3_ST	Q9Y2X7	GIT1	O94806	PRKD3	S571	F567L	567	Missense	distal	-4	no	2.230	2.236	EPSD	COSMIC	1.136	Up-regulation
CAMK_PKD_PRKD3_ST	Q9Y2X7	GIT1	O94806	PRKD3	S581	R582H	582	Missense	proximal	1	no	1.581	1.632	EPSD	COSMIC	1.136	Up-regulation
CAMK_PKD_PRKD3_ST	Q9Y2X7	GIT1	O94806	PRKD3	S585	R582H	582	Missense	distal	-3	no	1.980	1.953	EPSD	COSMIC	1.136	Down-regulation
CAMK_PKD_PRKD3_ST	Q9Y2X7	GIT1	O94806	PRKD3	S700	R703Q	703	Missense	distal	3	no	1.372	1.429	EPSD	COSMIC	1.136	Up-regulation
TK_PDGFR_CSF1R_Y	P07333	CSF1R	P07333	CSF1R	Y571	Y571D	571	Missense	central	0	yes	0.000	0.000	EPSD	COSMIC;GDSC;CCLE	0.000	Loss
TK_PDGFR_CSF1R_Y	P07333	CSF1R	P07333	CSF1R	Y699	Y699D	699	Missense	central	0	yes	0.001	0.000	EPSD;PhosphoSitePlus	COSMIC	0.000	Loss
TK_PDGFR_CSF1R_Y	P07333	CSF1R	P07333	CSF1R	Y969	Y969C	969	Missense	central	0	yes	0.001	0.000	EPSD	COSMIC	0.000	Loss
TK_PDGFR_CSF1R_Y	P07333	CSF1R	P07333	CSF1R	Y969	Y969F	969	Missense	central	0	yes	0.001	0.000	EPSD	COSMIC	0.000	Loss
TK_PDGFR_CSF1R_Y	P07333	CSF1R	P07333	CSF1R	Y969	Y969N	969	Missense	central	0	yes	0.001	0.000	EPSD	COSMIC	0.000	Loss
TK_PDGFR_CSF1R_Y	P07333	CSF1R	P07333	CSF1R	Y969	Y969H	969	Missense	central	0	yes	0.001	0.000	EPSD	COSMIC	0.000	Loss
TK_PDGFR_CSF1R_Y	P07333	CSF1R	P07333	CSF1R	Y969	Y969D	969	Missense	central	0	yes	0.001	0.000	EPSD	COSMIC	0.000	Loss
AGC_PKC_PKCa_PRKCB_ST	P10636	MAPT	P05771-2	PRKCB	T167	E165K	165	Missense	proximal	-2	no	0.079	1.523	EPSD	COSMIC	0.942	Gain
AGC_PKC_PKCa_PRKCB_ST	P10636	MAPT	P05771-2	PRKCB	S171	P175S	175	Missense	distal	4	no	2.924	2.789	EPSD	COSMIC	0.942	Down-regulation
AGC_PKC_PKCa_PRKCB_ST	P10636	MAPT	P05771-2	PRKCB	S171	A166V	166	Missense	distal	-5	no	2.924	2.895	EPSD	COSMIC;CCLE	0.942	Down-regulation
AGC_PKC_PKCa_PRKCB_ST	P10636	MAPT	P05771-2	PRKCB	S171	E176G	176	Missense	distal	5	no	2.924	2.603	EPSD	COSMIC	0.942	Down-regulation
AGC_PKC_PKCa_PRKCB_ST	P10636	MAPT	P05771-2	PRKCB	S171	D177G	177	Missense	distal	6	no	2.924	2.243	EPSD	COSMIC	0.942	Down-regulation
AGC_PKC_PKCa_PRKCB_ST	P10636	MAPT	P05771-2	PRKCB	S171	E165K	165	Missense	distal	-6	no	2.924	3.069	EPSD	COSMIC	0.942	Up-regulation
AGC_PKC_PKCa_PRKCB_ST	P10636	MAPT	P05771-2	PRKCB	S171	G172V	172	Missense	proximal	1	no	2.924	3.996	EPSD	COSMIC	0.942	Up-regulation
AGC_PKC_PKCa_PRKCB_ST	P10636	MAPT	P05771-2	PRKCB	S214	E210Q	210	Missense	distal	-4	no	1.656	1.568	EPSD	COSMIC	0.942	Down-regulation
AGC_PKC_PKCa_PRKCB_ST	P10636	MAPT	P05771-2	PRKCB	S214	G207E	207	Missense	distal	-7	no	1.656	1.463	EPSD	COSMIC	0.942	Down-regulation
AGC_PKC_PKCa_PRKCB_ST	P10636	MAPT	P05771-2	PRKCB	S228	Q230R	230	Missense	proximal	2	no	-4.307	2.242	EPSD	COSMIC	0.942	Gain
AGC_PKC_PKCa_PRKCB_ST	P10636	MAPT	P05771-2	PRKCB	S235	A237T	237	Missense	proximal	2	no	-1.607	1.750	EPSD	COSMIC	0.942	Gain
AGC_PKC_PKCa_PRKCB_ST	P10636	MAPT	P05771-2	PRKCB	S341	G343R	343	Missense	proximal	2	no	-2.002	6.732	EPSD	COSMIC	0.942	Gain
AGC_PKC_PKCa_PRKCB_ST	P10636	MAPT	P05771-2	PRKCB	S355	A361S	361	Missense	distal	6	no	3.476	3.834	EPSD	COSMIC;GDSC;CCLE	0.942	Up-regulation
AGC_PKC_PKCa_PRKCB_ST	P10636	MAPT	P05771-2	PRKCB	S355	P354L	354	Missense	proximal	-1	no	3.476	3.527	EPSD	COSMIC	0.942	Up-regulation
AGC_PKC_PKCa_PRKCB_ST	P10636	MAPT	P05771-2	PRKCB	S369	V368I	368	Missense	proximal	-1	no	3.530	3.422	EPSD	COSMIC	0.942	Down-regulation
AGC_PKC_PKCa_PRKCB_ST	P10636	MAPT	P05771-2	PRKCB	S369	R370W	370	Missense	proximal	1	no	3.530	0.857	EPSD	COSMIC	0.942	Loss
AGC_PKC_PKCa_PRKCB_ST	P10636	MAPT	P05771-2	PRKCB	S396	R398C	398	Missense	proximal	2	no	3.192	-1.301	EPSD	COSMIC	0.942	Loss
AGC_PKC_PKCa_PRKCB_ST	P10636	MAPT	P05771-2	PRKCB	S396	S396F	396	Missense	central	0	yes	3.192	0.000	EPSD	COSMIC	0.942	Loss
AGC_PKC_PKCa_PRKCB_ST	P10636	MAPT	P05771-2	PRKCB	S396	D389N	389	Missense	distal	-7	no	3.192	3.368	EPSD	COSMIC;GDSC;CCLE	0.942	Up-regulation
AGC_PKC_PKCa_PRKCB_ST	P10636	MAPT	P05771-2	PRKCB	S400	R398C	398	Missense	proximal	-2	no	5.186	3.720	EPSD	COSMIC	0.942	Down-regulation
AGC_PKC_PKCa_PRKCB_ST	P10636	MAPT	P05771-2	PRKCB	S400	S396F	396	Missense	distal	-4	no	5.186	5.164	EPSD	COSMIC	0.942	Down-regulation
AGC_PKC_PKCa_PRKCB_ST	P10636	MAPT	P05771-2	PRKCB	T403	L410F	410	Missense	distal	7	no	1.137	1.134	EPSD	COSMIC	0.942	Down-regulation
AGC_PKC_PKCa_PRKCB_ST	P10636	MAPT	P05771-2	PRKCB	T403	R398C	398	Missense	distal	-5	no	1.137	0.903	EPSD	COSMIC	0.942	Loss
AGC_PKC_PKCa_PRKCB_ST	P10636	MAPT	P05771-2	PRKCB	T403	S396F	396	Missense	distal	-7	no	1.137	1.209	EPSD	COSMIC	0.942	Up-regulation
AGC_PKC_PKCa_PRKCB_ST	P10636	MAPT	P05771-2	PRKCB	S438	S443Y	443	Missense	distal	5	no	1.209	1.302	EPSD	COSMIC	0.942	Up-regulation
AGC_PKC_PKCa_PRKCB_ST	P10636	MAPT	P05771-2	PRKCB	T470	T466M	466	Missense	distal	-4	no	3.997	4.034	EPSD	COSMIC;GDSC;CCLE	0.942	Up-regulation
AGC_PKC_PKCa_PRKCB_ST	P10636	MAPT	P05771-2	PRKCB	T470	K467T	467	Missense	distal	-3	no	3.997	1.284	EPSD	COSMIC	0.942	Down-regulation
AGC_PKC_PKCa_PRKCB_ST	P10636	MAPT	P05771-2	PRKCB	T470	P477L	477	Missense	distal	7	no	3.997	3.964	EPSD	COSMIC	0.942	Down-regulation
AGC_PKC_PKCa_PRKCB_ST	P10636	MAPT	P05771-2	PRKCB	T470	P477S	477	Missense	distal	7	no	3.997	3.904	EPSD	COSMIC	0.942	Down-regulation
AGC_PKC_PKCa_PRKCB_ST	P10636	MAPT	P05771-2	PRKCB	S525	G521V	521	Missense	distal	-4	no	1.150	0.969	EPSD	COSMIC	0.942	Down-regulation
AGC_PKC_PKCa_PRKCB_ST	P10636	MAPT	P05771-2	PRKCB	S525	R526H	526	Missense	proximal	1	no	1.150	-0.557	EPSD	COSMIC	0.942	Loss
AGC_PKC_PKCa_PRKCB_ST	P10636	MAPT	P05771-2	PRKCB	S525	G518V	518	Missense	distal	-7	no	1.150	1.075	EPSD	COSMIC	0.942	Down-regulation
AGC_PKC_PKCa_PRKCB_ST	P10636	MAPT	P05771-2	PRKCB	S525	R528S	528	Missense	distal	3	no	1.150	0.384	EPSD	COSMIC	0.942	Loss
AGC_PKC_PKCa_PRKCB_ST	P10636	MAPT	P05771-2	PRKCB	S525	P530S	530	Missense	distal	5	no	1.150	1.207	EPSD	COSMIC	0.942	Up-regulation
AGC_PKC_PKCa_PRKCB_ST	P10636	MAPT	P05771-2	PRKCB	S531	R526H	526	Missense	distal	-5	no	1.751	1.503	EPSD	COSMIC	0.942	Down-regulation
AGC_PKC_PKCa_PRKCB_ST	P10636	MAPT	P05771-2	PRKCB	S531	R528S	528	Missense	distal	-3	no	1.751	-1.646	EPSD	COSMIC	0.942	Loss
AGC_PKC_PKCa_PRKCB_ST	P10636	MAPT	P05771-2	PRKCB	S531	P530S	530	Missense	proximal	-1	no	1.751	1.810	EPSD	COSMIC	0.942	Up-regulation
AGC_PKC_PKCa_PRKCB_ST	P10636	MAPT	P05771-2	PRKCB	S531	P536H	536	Missense	distal	5	no	1.751	1.837	EPSD	COSMIC	0.942	Up-regulation
AGC_PKC_PKCa_PRKCB_ST	P10636	MAPT	P05771-2	PRKCB	S531	P535Q	535	Missense	distal	4	no	1.751	2.014	EPSD	COSMIC	0.942	Up-regulation
AGC_PKC_PKCa_PRKCB_ST	P10636	MAPT	P05771-2	PRKCB	S555	P550S	550	Missense	distal	-5	no	2.171	2.197	EPSD	COSMIC	0.942	Up-regulation
AGC_PKC_PKCa_PRKCB_ST	P10636	MAPT	P05771-2	PRKCB	S555	R559C	559	Missense	distal	4	no	2.171	1.032	EPSD	COSMIC	0.942	Down-regulation
AGC_PKC_PKCa_PRKCB_ST	P10636	MAPT	P05771-2	PRKCB	S555	P553R	553	Missense	proximal	-2	no	2.171	4.003	EPSD	COSMIC	0.942	Up-regulation
AGC_PKC_PKCa_PRKCB_ST	P10636	MAPT	P05771-2	PRKCB	S555	P553L	553	Missense	proximal	-2	no	2.171	1.483	EPSD	COSMIC	0.942	Down-regulation
AGC_PKC_PKCa_PRKCB_ST	P10636	MAPT	P05771-2	PRKCB	S555	P549L	549	Missense	distal	-6	no	2.171	2.186	EPSD	COSMIC	0.942	Up-regulation
AGC_PKC_PKCa_PRKCB_ST	P10636	MAPT	P05771-2	PRKCB	S555	S555F	555	Missense	central	0	yes	2.171	0.000	EPSD	COSMIC	0.942	Loss
AGC_PKC_PKCa_PRKCB_ST	P10636	MAPT	P05771-2	PRKCB	S555	P553Q	553	Missense	proximal	-2	no	2.171	3.031	EPSD	COSMIC	0.942	Up-regulation
AGC_PKC_PKCa_PRKCB_ST	P10636	MAPT	P05771-2	PRKCB	S606	N613D	613	Missense	distal	7	no	1.921	1.841	EPSD	COSMIC	0.942	Down-regulation
AGC_PKC_PKCa_PRKCB_ST	P10636	MAPT	P05771-2	PRKCB	S606	S602G	602	Missense	distal	-4	no	1.921	2.014	EPSD	COSMIC	0.942	Up-regulation
AGC_PKC_PKCa_PRKCB_ST	P10636	MAPT	P05771-2	PRKCB	S606	C608W	608	Missense	proximal	2	no	1.921	-3.099	EPSD	COSMIC	0.942	Loss
AGC_PKC_PKCa_PRKCB_ST	P10636	MAPT	P05771-2	PRKCB	S606	S610L	610	Missense	distal	4	no	1.921	1.633	EPSD	COSMIC	0.942	Down-regulation
AGC_PKC_PKCa_PRKCB_ST	P10636	MAPT	P05771-2	PRKCB	S606	D600E	600	Missense	distal	-6	no	1.921	2.018	EPSD	COSMIC	0.942	Up-regulation
AGC_PKC_PKCa_PRKCB_ST	P10636	MAPT	P05771-2	PRKCB	S610	N613D	613	Missense	distal	3	no	2.799	2.743	EPSD	COSMIC	0.942	Down-regulation
AGC_PKC_PKCa_PRKCB_ST	P10636	MAPT	P05771-2	PRKCB	S610	C608W	608	Missense	proximal	-2	no	2.799	0.988	EPSD	COSMIC	0.942	Down-regulation
AGC_PKC_PKCa_PRKCB_ST	P10636	MAPT	P05771-2	PRKCB	S610	S610L	610	Missense	central	0	yes	2.799	0.000	EPSD	COSMIC	0.942	Loss
AGC_PKC_PKCa_PRKCB_ST	P10636	MAPT	P05771-2	PRKCB	S633	S633N	633	Missense	central	0	yes	1.139	0.000	EPSD	COSMIC	0.942	Loss
AGC_PKC_PKCa_PRKCB_ST	P10636	MAPT	P05771-2	PRKCB	S633	S633I	633	Missense	central	0	yes	1.139	0.000	EPSD	COSMIC	0.942	Loss
AGC_PKC_PKCa_PRKCB_ST	P10636	MAPT	P05771-2	PRKCB	S637	S633N	633	Missense	distal	-4	no	4.072	4.054	EPSD	COSMIC	0.942	Down-regulation
AGC_PKC_PKCa_PRKCB_ST	P10636	MAPT	P05771-2	PRKCB	S637	S633I	633	Missense	distal	-4	no	4.072	4.043	EPSD	COSMIC	0.942	Down-regulation
AGC_PKC_PKCa_PRKCB_ST	P10636	MAPT	P05771-2	PRKCB	S658	D662G	662	Missense	distal	4	no	3.767	3.353	EPSD	COSMIC	0.942	Down-regulation
AGC_PKC_PKCa_PRKCB_ST	P10636	MAPT	P05771-2	PRKCB	S658	K664N	664	Missense	distal	6	no	3.767	3.138	EPSD	COSMIC	0.942	Down-regulation
AGC_PKC_PKCa_PRKCB_ST	P10636	MAPT	P05771-2	PRKCB	S669	S669L	669	Missense	central	0	yes	3.675	0.000	EPSD	COSMIC	0.942	Loss
AGC_PKC_PKCa_PRKCB_ST	P10636	MAPT	P05771-2	PRKCB	S669	R666K	666	Missense	distal	-3	no	3.675	3.906	EPSD	COSMIC	0.942	Up-regulation
AGC_PKC_PKCa_PRKCB_ST	P10636	MAPT	P05771-2	PRKCB	S669	D662G	662	Missense	distal	-7	no	3.675	3.945	EPSD	COSMIC	0.942	Up-regulation
AGC_PKC_PKCa_PRKCB_ST	P10636	MAPT	P05771-2	PRKCB	S669	S673F	673	Missense	distal	4	no	3.675	3.525	EPSD	COSMIC	0.942	Down-regulation
AGC_PKC_PKCa_PRKCB_ST	P10636	MAPT	P05771-2	PRKCB	S669	K670N	670	Missense	proximal	1	no	3.675	0.855	EPSD	COSMIC	0.942	Loss
AGC_PKC_PKCa_PRKCB_ST	P10636	MAPT	P05771-2	PRKCB	S669	K664N	664	Missense	distal	-5	no	3.675	3.508	EPSD	COSMIC	0.942	Down-regulation
AGC_PKC_PKCa_PRKCB_ST	P10636	MAPT	P05771-2	PRKCB	S669	L674Q	674	Missense	distal	5	no	3.675	4.154	EPSD	COSMIC	0.942	Up-regulation
AGC_PKC_PKCa_PRKCB_ST	P10636	MAPT	P05771-2	PRKCB	T690	R696H	696	Missense	distal	6	no	3.504	2.744	EPSD	COSMIC	0.942	Down-regulation
AGC_PKC_PKCa_PRKCB_ST	P10636	MAPT	P05771-2	PRKCB	T690	G683R	683	Missense	distal	-7	no	3.504	3.152	EPSD	COSMIC;CCLE	0.942	Down-regulation
AGC_PKC_PKCa_PRKCB_ST	P10636	MAPT	P05771-2	PRKCB	T690	G683E	683	Missense	distal	-7	no	3.504	3.312	EPSD	COSMIC	0.942	Down-regulation
AGC_PKC_PKCa_PRKCB_ST	P10636	MAPT	P05771-2	PRKCB	T690	R696C	696	Missense	distal	6	no	3.504	2.309	EPSD	COSMIC	0.942	Down-regulation
AGC_PKC_PKCa_PRKCB_ST	P10636	MAPT	P05771-2	PRKCB	T690	G684E	684	Missense	distal	-6	no	3.504	3.771	EPSD	COSMIC	0.942	Up-regulation
AGC_PKC_PKCa_PRKCB_ST	P10636	MAPT	P05771-2	PRKCB	T694	R696H	696	Missense	proximal	2	no	2.834	-3.528	EPSD	COSMIC	0.942	Loss
AGC_PKC_PKCa_PRKCB_ST	P10636	MAPT	P05771-2	PRKCB	T694	R696C	696	Missense	proximal	2	no	2.834	-1.659	EPSD	COSMIC	0.942	Loss
AGC_PKC_PKCa_PRKCB_ST	P10636	MAPT	P05771-2	PRKCB	S721	R723W	723	Missense	proximal	2	no	2.050	-7.464	EPSD	COSMIC	0.942	Loss
AGC_PKC_PKCa_PRKCB_ST	P10636	MAPT	P05771-2	PRKCB	S721	V728M	728	Missense	distal	7	no	2.050	2.047	EPSD	COSMIC	0.942	Down-regulation
AGC_PKC_PKCa_PRKCB_ST	P10636	MAPT	P05771-2	PRKCB	S721	V728A	728	Missense	distal	7	no	2.050	2.105	EPSD	COSMIC	0.942	Up-regulation
AGC_PKC_PKCa_PRKCB_ST	P05107	ITGB2	P05771-2	PRKCB	T118	A112T	112	Missense	distal	-6	no	4.279	4.419	EPSD	COSMIC	0.942	Up-regulation
AGC_PKC_PKCa_PRKCB_ST	P05107	ITGB2	P05771-2	PRKCB	S496	S503F	503	Missense	distal	7	no	3.467	3.525	EPSD	COSMIC	0.942	Up-regulation
AGC_PKC_PKCa_PRKCB_ST	P05107	ITGB2	P05771-2	PRKCB	S591	R586W	586	Missense	distal	-5	no	5.199	4.821	EPSD	COSMIC	0.942	Down-regulation
AGC_PKC_PKCa_PRKCB_ST	P05107	ITGB2	P05771-2	PRKCB	S591	R595Q	595	Missense	distal	4	no	5.199	4.580	EPSD	COSMIC;GDSC	0.942	Down-regulation
AGC_PKC_PKCa_PRKCB_ST	P05107	ITGB2	P05771-2	PRKCB	S591	R593H	593	Missense	proximal	2	no	5.199	-1.162	EPSD	COSMIC	0.942	Loss
AGC_PKC_PKCa_PRKCB_ST	Q8NER1	TRPV1	P05771-2	PRKCB	S5	S6N	6	Missense	proximal	1	no	3.198	2.516	EPSD	COSMIC;GDSC;CCLE	0.942	Down-regulation
AGC_PKC_PKCa_PRKCB_ST	Q8NER1	TRPV1	P05771-2	PRKCB	S502	M503I	503	Missense	proximal	1	no	4.026	5.036	EPSD	COSMIC	0.942	Up-regulation
AGC_PKC_PKCa_PRKCB_ST	Q8NER1	TRPV1	P05771-2	PRKCB	S502	T505A	505	Missense	distal	3	no	4.026	3.632	EPSD	COSMIC	0.942	Down-regulation
AGC_PKC_PKCa_PRKCB_ST	Q8NER1	TRPV1	P05771-2	PRKCB	S502	F507L	507	Missense	distal	5	no	4.026	4.020	EPSD	COSMIC	0.942	Down-regulation
AGC_PKC_PKCa_PRKCB_ST	Q8NER1	TRPV1	P05771-2	PRKCB	S502	T505I	505	Missense	distal	3	no	4.026	3.639	EPSD	COSMIC	0.942	Down-regulation
AGC_PKC_PKCa_PRKCB_ST	Q8NER1	TRPV1	P05771-2	PRKCB	S502	R500W	500	Missense	proximal	-2	no	4.026	0.749	EPSD	COSMIC	0.942	Loss
AGC_PKC_PKCa_PRKCB_ST	Q8NER1	TRPV1	P05771-2	PRKCB	T705	K711R	711	Missense	distal	6	no	2.523	2.372	PhosphoSitePlus	COSMIC	0.942	Down-regulation
AGC_PKC_PKCa_PRKCB_ST	Q8NER1	TRPV1	P05771-2	PRKCB	S712	K711R	711	Missense	proximal	-1	no	2.279	2.455	EPSD	COSMIC	0.942	Up-regulation
AGC_PKC_PKCa_PRKCB_ST	Q8NER1	TRPV1	P05771-2	PRKCB	S712	M717T	717	Missense	distal	5	no	2.279	2.377	EPSD	COSMIC	0.942	Up-regulation
AGC_PKC_PKCa_PRKCB_ST	Q8NER1	TRPV1	P05771-2	PRKCB	S712	L714V	714	Missense	proximal	2	no	2.279	3.608	EPSD	COSMIC	0.942	Up-regulation
AGC_PKC_PKCa_PRKCB_ST	Q8NER1	TRPV1	P05771-2	PRKCB	S777	R772S	772	Missense	distal	-5	no	3.143	2.895	EPSD	COSMIC	0.942	Down-regulation
AGC_PKC_PKCa_PRKCB_ST	Q8NER1	TRPV1	P05771-2	PRKCB	S777	K771R	771	Missense	distal	-6	no	3.143	3.083	EPSD	COSMIC	0.942	Down-regulation
AGC_PKC_PKCa_PRKCB_ST	Q8NER1	TRPV1	P05771-2	PRKCB	S801	P795L	795	Missense	distal	-6	no	7.183	7.198	EPSD	COSMIC	0.942	Up-regulation
AGC_PKC_PKCa_PRKCB_ST	P98082	DAB2	P05771-2	PRKCB	S24	K26M	26	Missense	proximal	2	no	12.413	7.275	PhosphoSitePlus	COSMIC	0.942	Down-regulation
AGC_PKC_PKCa_PRKCB_ST	P98082	DAB2	P05771-2	PRKCB	S24	P23L	23	Missense	proximal	-1	no	12.413	12.464	PhosphoSitePlus	COSMIC	0.942	Up-regulation
AGC_PKC_PKCa_PRKCB_ST	P98082	DAB2	P05771-2	PRKCB	S24	G31V	31	Missense	distal	7	no	12.413	12.345	PhosphoSitePlus	COSMIC	0.942	Down-regulation
AGC_PKC_PKCa_PRKCB_ST	P98082	DAB2	P05771-2	PRKCB	S24	A18S	18	Missense	distal	-6	no	12.413	12.490	PhosphoSitePlus	COSMIC	0.942	Up-regulation
AGC_PKC_PKCa_PRKCB_ST	P98082	DAB2	P05771-2	PRKCB	S249	E252Q	252	Missense	distal	3	no	4.764	4.603	EPSD	COSMIC	0.942	Down-regulation
AGC_PKC_PKCa_PRKCB_ST	P98082	DAB2	P05771-2	PRKCB	S313	F311L	311	Missense	proximal	-2	no	1.710	1.878	EPSD	COSMIC;CCLE	0.942	Up-regulation
AGC_PKC_PKCa_PRKCB_ST	P98082	DAB2	P05771-2	PRKCB	S313	Q319P	319	Missense	distal	6	no	1.710	1.958	EPSD	COSMIC	0.942	Up-regulation
AGC_PKC_PKCa_PRKCB_ST	P98082	DAB2	P05771-2	PRKCB	S313	T307A	307	Missense	distal	-6	no	1.710	1.569	EPSD	COSMIC	0.942	Down-regulation
AGC_PKC_PKCa_PRKCB_ST	P98082	DAB2	P05771-2	PRKCB	S390	V391I	391	Missense	proximal	1	no	3.515	3.802	EPSD	COSMIC	0.942	Up-regulation
AGC_PKC_PKCa_PRKCB_ST	P98082	DAB2	P05771-2	PRKCB	S390	R384G	384	Missense	distal	-6	no	3.515	3.163	EPSD	COSMIC	0.942	Down-regulation
AGC_PKC_PKCa_PRKCB_ST	P98082	DAB2	P05771-2	PRKCB	S407	V412I	412	Missense	distal	5	no	1.602	1.695	EPSD	COSMIC	0.942	Up-regulation
AGC_PKC_PKCa_PRKCB_ST	P98082	DAB2	P05771-2	PRKCB	S407	P403L	403	Missense	distal	-4	no	1.602	1.564	EPSD	COSMIC	0.942	Down-regulation
AGC_PKC_PKCa_PRKCB_ST	P98082	DAB2	P05771-2	PRKCB	S436	G440R	440	Missense	distal	4	no	1.854	3.210	EPSD	COSMIC	0.942	Up-regulation
AGC_PKC_PKCa_PRKCB_ST	P98082	DAB2	P05771-2	PRKCB	S436	I431M	431	Missense	distal	-5	no	1.854	1.781	EPSD	COSMIC	0.942	Down-regulation
AGC_PKC_PKCa_PRKCB_ST	P98082	DAB2	P05771-2	PRKCB	S436	G442D	442	Missense	distal	6	no	1.854	2.535	EPSD	COSMIC	0.942	Up-regulation
AGC_PKC_PKCa_PRKCB_ST	P98082	DAB2	P05771-2	PRKCB	S436	R443W	443	Missense	distal	7	no	1.854	2.155	EPSD	COSMIC	0.942	Up-regulation
AGC_PKC_PKCa_PRKCB_ST	P98082	DAB2	P05771-2	PRKCB	S436	R443L	443	Missense	distal	7	no	1.854	2.084	EPSD	COSMIC	0.942	Up-regulation
AGC_PKC_PKCa_PRKCB_ST	P98082	DAB2	P05771-2	PRKCB	S471	T473K	473	Missense	proximal	2	no	-1.692	1.328	EPSD	COSMIC	0.942	Gain
AGC_PKC_PKCa_PRKCB_ST	P98082	DAB2	P05771-2	PRKCB	S723	V722I	722	Missense	proximal	-1	no	1.537	1.428	EPSD	COSMIC	0.942	Down-regulation
AGC_PKC_PKCa_PRKCB_ST	P98082	DAB2	P05771-2	PRKCB	S723	Q721K	721	Missense	proximal	-2	no	1.537	2.619	EPSD	COSMIC	0.942	Up-regulation
AGC_PKC_PKCa_PRKCB_ST	P98082	DAB2	P05771-2	PRKCB	S723	L724M	724	Missense	proximal	1	no	1.537	0.461	EPSD	COSMIC	0.942	Loss
AGC_PKC_PKCa_PRKCB_ST	P98082	DAB2	P05771-2	PRKCB	S723	K716N	716	Missense	distal	-7	no	1.537	1.839	EPSD	COSMIC	0.942	Up-regulation
AGC_PKC_PKCa_PRKCB_ST	P98082	DAB2	P05771-2	PRKCB	S723	Q721H	721	Missense	proximal	-2	no	1.537	0.493	EPSD	COSMIC	0.942	Loss
AGC_PKC_PKCa_PRKCB_ST	P98082	DAB2	P05771-2	PRKCB	S723	P725S	725	Missense	proximal	2	no	1.537	1.372	EPSD	COSMIC	0.942	Down-regulation
AGC_PKC_PKCa_PRKCB_ST	P98082	DAB2	P05771-2	PRKCB	S723	A718D	718	Missense	distal	-5	no	1.537	1.604	EPSD	COSMIC	0.942	Up-regulation
AGC_PKC_PKCa_PRKCB_ST	P98082	DAB2	P05771-2	PRKCB	S723	A718S	718	Missense	distal	-5	no	1.537	1.495	EPSD	COSMIC	0.942	Down-regulation
AGC_PKC_PKCa_PRKCB_ST	P05771	PRKCB	P05771-2	PRKCB	S16	R22G	22	Missense	distal	6	no	2.322	0.895	EPSD	COSMIC	0.942	Loss
AGC_PKC_PKCa_PRKCB_ST	P05771	PRKCB	P05771-2	PRKCB	T17	R22G	22	Missense	distal	5	no	3.564	3.134	EPSD	COSMIC	0.942	Down-regulation
AGC_PKC_PKCa_PRKCB_ST	P05771	PRKCB	P05771-2	PRKCB	T17	G24D	24	Missense	distal	7	no	3.564	3.337	EPSD	COSMIC	0.942	Down-regulation
AGC_PKC_PKCa_PRKCB_ST	P05771	PRKCB	P05771-2	PRKCB	T40	T40A	40	Missense	central	0	yes	3.397	0.000	EPSD	COSMIC	0.942	Loss
AGC_PKC_PKCa_PRKCB_ST	P05771	PRKCB	P05771-2	PRKCB	T40	N36T	36	Missense	distal	-4	no	3.397	3.365	EPSD	COSMIC	0.942	Down-regulation
AGC_PKC_PKCa_PRKCB_ST	P05771	PRKCB	P05771-2	PRKCB	T48	C50S	50	Missense	proximal	2	no	2.065	0.561	EPSD	COSMIC	0.942	Loss
AGC_PKC_PKCa_PRKCB_ST	P05771	PRKCB	P05771-2	PRKCB	T48	D55H	55	Missense	distal	7	no	2.065	2.217	EPSD	COSMIC	0.942	Up-regulation
AGC_PKC_PKCa_PRKCB_ST	P05771	PRKCB	P05771-2	PRKCB	T48	C53Y	53	Missense	distal	5	no	2.065	2.195	EPSD	COSMIC	0.942	Up-regulation
AGC_PKC_PKCa_PRKCB_ST	P05771	PRKCB	P05771-2	PRKCB	S111	T108M	108	Missense	distal	-3	no	2.681	2.160	EPSD	COSMIC	0.942	Down-regulation
AGC_PKC_PKCa_PRKCB_ST	P05771	PRKCB	P05771-2	PRKCB	S111	Y109H	109	Missense	proximal	-2	no	2.681	2.308	EPSD	COSMIC	0.942	Down-regulation
AGC_PKC_PKCa_PRKCB_ST	P05771	PRKCB	P05771-2	PRKCB	T314	K320R	320	Missense	distal	6	no	1.587	1.436	EPSD	COSMIC	0.942	Down-regulation
AGC_PKC_PKCa_PRKCB_ST	P05771	PRKCB	P05771-2	PRKCB	T314	K320N	320	Missense	distal	6	no	1.587	0.958	EPSD	COSMIC	0.942	Down-regulation
AGC_PKC_PKCa_PRKCB_ST	P05771	PRKCB	P05771-2	PRKCB	T314	I310T	310	Missense	distal	-4	no	1.587	1.566	EPSD	COSMIC	0.942	Down-regulation
AGC_PKC_PKCa_PRKCB_ST	P05771	PRKCB	P05771-2	PRKCB	T314	P317L	317	Missense	distal	3	no	1.587	1.200	EPSD	COSMIC	0.942	Down-regulation
AGC_PKC_PKCa_PRKCB_ST	P05771	PRKCB	P05771-2	PRKCB	T314	G313V	313	Missense	proximal	-1	no	1.587	1.648	EPSD	COSMIC	0.942	Up-regulation
AGC_PKC_PKCa_PRKCB_ST	P05771	PRKCB	P05771-2	PRKCB	T314	A308T	308	Missense	distal	-6	no	1.587	1.728	EPSD	COSMIC	0.942	Up-regulation
AGC_PKC_PKCa_PRKCB_ST	P05771	PRKCB	P05771-2	PRKCB	T364	E366K	366	Missense	proximal	2	no	-2.663	2.750	EPSD	COSMIC	0.942	Gain
AGC_PKC_PKCa_PRKCB_ST	P05771	PRKCB	P05771-2	PRKCB	T500	P505T	505	Missense	distal	5	no	2.613	2.737	EPSD	COSMIC	0.942	Up-regulation
AGC_PKC_PKCa_PRKCB_ST	P05771	PRKCB	P05771-2	PRKCB	T500	T504I	504	Missense	distal	4	no	2.613	2.783	EPSD	COSMIC	0.942	Up-regulation
AGC_PKC_PKCa_PRKCB_ST	P05771	PRKCB	P05771-2	PRKCB	T500	T498S	498	Missense	proximal	-2	no	2.613	2.047	EPSD	COSMIC	0.942	Down-regulation
AGC_PKC_PKCa_PRKCB_ST	P05771	PRKCB	P05771-2	PRKCB	T500	V496M	496	Missense	distal	-4	no	2.613	2.689	EPSD	COSMIC	0.942	Up-regulation
AGC_PKC_PKCa_PRKCB_ST	P05771	PRKCB	P05771-2	PRKCB	T500	T504N	504	Missense	distal	4	no	2.613	2.969	EPSD	COSMIC	0.942	Up-regulation
AGC_PKC_PKCa_PRKCB_ST	P05771	PRKCB	P05771-2	PRKCB	S565	A568T	568	Missense	distal	3	no	0.626	1.019	EPSD	COSMIC	0.942	Gain
AGC_PKC_PKCa_PRKCB_ST	P53004	BLVRA	P05771-2	PRKCB	S21	S21F	21	Missense	central	0	yes	6.698	0.000	EPSD	COSMIC	0.942	Loss
AGC_PKC_PKCa_PRKCB_ST	P53004	BLVRA	P05771-2	PRKCB	S230	R225Q	225	Missense	distal	-5	no	1.308	1.290	PhosphoSitePlus;EPSD	COSMIC	0.942	Down-regulation
AGC_PKC_PKCa_PRKCB_ST	P53004	BLVRA	P05771-2	PRKCB	S230	S235Y	235	Missense	distal	5	no	1.308	1.401	PhosphoSitePlus;EPSD	COSMIC	0.942	Up-regulation
AGC_PKC_PKCa_PRKCB_ST	P53004	BLVRA	P05771-2	PRKCB	S230	R227K	227	Missense	distal	-3	no	1.308	1.539	PhosphoSitePlus;EPSD	COSMIC	0.942	Up-regulation
AGC_PKC_PKCa_PRKCB_ST	Q07869	PPARA	P05771-2	PRKCB	S179	E180Q	180	Missense	proximal	1	no	2.928	4.108	EPSD;PhosphoSitePlus	COSMIC	0.942	Up-regulation
AGC_PKC_PKCa_PRKCB_ST	Q07869	PPARA	P05771-2	PRKCB	S230	R226W	226	Missense	distal	-4	no	2.949	3.527	PhosphoSitePlus;EPSD	COSMIC	0.942	Up-regulation
AGC_PKC_PKCa_PRKCB_ST	P15336	ATF2	P05771-2	PRKCB	S100	M107I	107	Missense	distal	7	no	5.803	5.744	EPSD	COSMIC;GDSC;CCLE	0.942	Down-regulation
AGC_PKC_PKCa_PRKCB_ST	P15336	ATF2	P05771-2	PRKCB	S100	K105T	105	Missense	distal	5	no	5.803	5.402	EPSD	COSMIC;GDSC;CCLE	0.942	Down-regulation
AGC_PKC_PKCa_PRKCB_ST	P15336	ATF2	P05771-2	PRKCB	S100	K106R	106	Missense	distal	6	no	5.803	5.652	EPSD	COSMIC	0.942	Down-regulation
AGC_PKC_PKCa_PRKCB_ST	P15336	ATF2	P05771-2	PRKCB	T253	S257R	257	Missense	distal	4	no	0.009	1.027	EPSD	COSMIC	0.942	Gain
AGC_PKC_PKCa_PRKCB_ST	P15336	ATF2	P05771-2	PRKCB	S314	R311Q	311	Missense	distal	-3	no	1.491	-1.707	EPSD	COSMIC;GDSC;CCLE	0.942	Loss
AGC_PKC_PKCa_PRKCB_ST	P15336	ATF2	P05771-2	PRKCB	S314	Q316K	316	Missense	proximal	2	no	1.491	6.417	EPSD	COSMIC	0.942	Up-regulation
AGC_PKC_PKCa_PRKCB_ST	P15336	ATF2	P05771-2	PRKCB	S314	Q317H	317	Missense	distal	3	no	1.491	1.250	EPSD	COSMIC	0.942	Down-regulation
AGC_PKC_PKCa_PRKCB_ST	P15336	ATF2	P05771-2	PRKCB	S340	Q337K	337	Missense	distal	-3	no	2.871	6.301	EPSD	COSMIC	0.942	Up-regulation
AGC_PKC_PKCa_PRKCB_ST	P15336	ATF2	P05771-2	PRKCB	S340	Q335H	335	Missense	distal	-5	no	2.871	2.641	EPSD	COSMIC	0.942	Down-regulation
AGC_PKC_PKCa_PRKCB_ST	P15336	ATF2	P05771-2	PRKCB	S340	R343L	343	Missense	distal	3	no	2.871	1.786	EPSD	COSMIC	0.942	Down-regulation
AGC_PKC_PKCa_PRKCB_ST	P15336	ATF2	P05771-2	PRKCB	S340	P334S	334	Missense	distal	-6	no	2.871	2.985	EPSD	COSMIC	0.942	Up-regulation
AGC_PKC_PKCa_PRKCB_ST	P15336	ATF2	P05771-2	PRKCB	S340	R345T	345	Missense	distal	5	no	2.871	2.531	EPSD	COSMIC	0.942	Down-regulation
AGC_PKC_PKCa_PRKCB_ST	P15336	ATF2	P05771-2	PRKCB	S340	R343Q	343	Missense	distal	3	no	2.871	2.307	EPSD	COSMIC	0.942	Down-regulation
AGC_PKC_PKCa_PRKCB_ST	P15336	ATF2	P05771-2	PRKCB	S340	A347T	347	Missense	distal	7	no	2.871	2.781	EPSD	COSMIC	0.942	Down-regulation
AGC_PKC_PKCa_PRKCB_ST	P15336	ATF2	P05771-2	PRKCB	S340	R345K	345	Missense	distal	5	no	2.871	2.933	EPSD	COSMIC	0.942	Up-regulation
AGC_PKC_PKCa_PRKCB_ST	P15336	ATF2	P05771-2	PRKCB	S367	A364T	364	Missense	distal	-3	no	0.774	2.220	EPSD	COSMIC	0.942	Gain
AGC_PKC_PKCa_PRKCB_ST	P15336	ATF2	P05771-2	PRKCB	S367	A365T	365	Missense	proximal	-2	no	0.774	1.179	EPSD	COSMIC	0.942	Gain
AGC_PKC_PKCa_PRKCB_ST	P43629	KIR3DL1	P05771-2	PRKCB	S225	E222K	222	Missense	distal	-3	no	-0.332	3.003	EPSD	COSMIC	0.942	Gain
AGC_PKC_PKCa_PRKCB_ST	P43629	KIR3DL1	P05771-2	PRKCB	S245	E238K	238	Missense	distal	-7	no	3.334	3.130	EPSD	COSMIC	0.942	Down-regulation
AGC_PKC_PKCa_PRKCB_ST	P43629	KIR3DL1	P05771-2	PRKCB	S245	S249F	249	Missense	distal	4	no	3.334	3.185	EPSD	COSMIC;GDSC;CCLE	0.942	Down-regulation
AGC_PKC_PKCa_PRKCB_ST	P43629	KIR3DL1	P05771-2	PRKCB	S415	R413P	413	Missense	proximal	-2	no	7.824	5.992	PhosphoSitePlus	COSMIC	0.942	Down-regulation
AGC_PKC_PKCa_PRKCB_ST	P43629	KIR3DL1	P05771-2	PRKCB	S415	R409T	409	Missense	distal	-6	no	7.824	7.674	PhosphoSitePlus	COSMIC	0.942	Down-regulation
AGC_PKC_PKCa_PRKCB_ST	P43629	KIR3DL1	P05771-2	PRKCB	S415	K419E	419	Missense	distal	4	no	7.824	7.233	PhosphoSitePlus	COSMIC	0.942	Down-regulation
AGC_PKC_PKCa_PRKCB_ST	P43629	KIR3DL1	P05771-2	PRKCB	S415	I411S	411	Missense	distal	-4	no	7.824	7.852	PhosphoSitePlus	COSMIC	0.942	Up-regulation
AGC_PKC_PKCa_PRKCB_ST	P56537	EIF6	P05771-2	PRKCB	S6	S6L	6	Missense	central	0	yes	1.585	0.000	EPSD	COSMIC	0.942	Loss
AGC_PKC_PKCa_PRKCB_ST	Q06124	PTPN11	P05771-2	PRKCB	S28	P33S	33	Missense	distal	5	no	0.909	0.966	EPSD	COSMIC	0.942	Gain
AGC_PKC_PKCa_PRKCB_ST	Q06124	PTPN11	P05771-2	PRKCB	S140	E139K	139	Missense	proximal	-1	no	1.121	1.265	EPSD	COSMIC	0.942	Up-regulation
AGC_PKC_PKCa_PRKCB_ST	Q06124	PTPN11	P05771-2	PRKCB	S140	G133D	133	Missense	distal	-7	no	1.121	0.851	EPSD	COSMIC	0.942	Loss
AGC_PKC_PKCa_PRKCB_ST	Q06124	PTPN11	P05771-2	PRKCB	S140	G133C	133	Missense	distal	-7	no	1.121	0.984	EPSD	COSMIC	0.942	Down-regulation
AGC_PKC_PKCa_PRKCB_ST	Q06124	PTPN11	P05771-2	PRKCB	S140	R138Q	138	Missense	proximal	-2	no	1.121	0.149	EPSD	COSMIC	0.942	Loss
AGC_PKC_PKCa_PRKCB_ST	Q06124	PTPN11	P05771-2	PRKCB	S142	E139K	139	Missense	distal	-3	no	-2.308	1.027	EPSD	COSMIC	0.942	Gain
AGC_PKC_PKCa_PRKCB_ST	Q06124	PTPN11	P05771-2	PRKCB	S160	G163C	163	Missense	distal	3	no	0.985	1.160	EPSD	COSMIC	0.942	Up-regulation
AGC_PKC_PKCa_PRKCB_ST	Q06124	PTPN11	P05771-2	PRKCB	T397	T397M	397	Missense	central	0	yes	1.295	0.000	EPSD	COSMIC	0.942	Loss
AGC_PKC_PKCa_PRKCB_ST	Q06124	PTPN11	P05771-2	PRKCB	T397	A392V	392	Missense	distal	-5	no	1.295	1.266	EPSD	COSMIC	0.942	Down-regulation
AGC_PKC_PKCa_PRKCB_ST	Q06124	PTPN11	P05771-2	PRKCB	T415	E416G	416	Missense	proximal	1	no	1.289	1.058	EPSD	COSMIC	0.942	Down-regulation
AGC_PKC_PKCa_PRKCB_ST	Q06124	PTPN11	P05771-2	PRKCB	T415	T415M	415	Missense	central	0	yes	1.289	0.000	EPSD	COSMIC	0.942	Loss
AGC_PKC_PKCa_PRKCB_ST	Q06124	PTPN11	P05771-2	PRKCB	T415	G413W	413	Missense	proximal	-2	no	1.289	-0.120	EPSD	COSMIC	0.942	Loss
AGC_PKC_PKCa_PRKCB_ST	Q06124	PTPN11	P05771-2	PRKCB	S503	M508V	508	Missense	distal	5	no	3.497	3.523	EPSD	COSMIC	0.942	Up-regulation
AGC_PKC_PKCa_PRKCB_ST	Q06124	PTPN11	P05771-2	PRKCB	S503	R502W	502	Missense	proximal	-1	no	3.497	2.628	EPSD	COSMIC	0.942	Down-regulation
AGC_PKC_PKCa_PRKCB_ST	Q06124	PTPN11	P05771-2	PRKCB	S503	S506L	506	Missense	distal	3	no	3.497	3.177	EPSD	COSMIC	0.942	Down-regulation
AGC_PKC_PKCa_PRKCB_ST	Q06124	PTPN11	P05771-2	PRKCB	S503	V509I	509	Missense	distal	6	no	3.497	3.615	EPSD	COSMIC	0.942	Up-regulation
AGC_PKC_PKCa_PRKCB_ST	Q06124	PTPN11	P05771-2	PRKCB	S503	Q504E	504	Missense	proximal	1	no	3.497	2.317	EPSD	COSMIC	0.942	Down-regulation
AGC_PKC_PKCa_PRKCB_ST	Q06124	PTPN11	P05771-2	PRKCB	S503	G507V	507	Missense	distal	4	no	3.497	3.917	EPSD	COSMIC	0.942	Up-regulation
AGC_PKC_PKCa_PRKCB_ST	Q06124	PTPN11	P05771-2	PRKCB	S503	G507R	507	Missense	distal	4	no	3.497	4.853	EPSD	COSMIC	0.942	Up-regulation
AGC_PKC_PKCa_PRKCB_ST	Q06124	PTPN11	P05771-2	PRKCB	S503	Q510K	510	Missense	distal	7	no	3.497	3.532	EPSD	COSMIC	0.942	Up-regulation
AGC_PKC_PKCa_PRKCB_ST	Q06124	PTPN11	P05771-2	PRKCB	S503	R505K	505	Missense	proximal	2	no	3.497	1.874	EPSD	COSMIC	0.942	Down-regulation
AGC_PKC_PKCa_PRKCB_ST	Q06124	PTPN11	P05771-2	PRKCB	S503	S506P	506	Missense	distal	3	no	3.497	3.564	EPSD	COSMIC	0.942	Up-regulation
AGC_PKC_PKCa_PRKCB_ST	Q06124	PTPN11	P05771-2	PRKCB	S503	G507E	507	Missense	distal	4	no	3.497	4.148	EPSD	COSMIC	0.942	Up-regulation
AGC_PKC_PKCa_PRKCB_ST	Q06124	PTPN11	P05771-2	PRKCB	S503	G507A	507	Missense	distal	4	no	3.497	3.365	EPSD	COSMIC	0.942	Down-regulation
AGC_PKC_PKCa_PRKCB_ST	Q06124	PTPN11	P05771-2	PRKCB	S503	R502Q	502	Missense	proximal	-1	no	3.497	3.312	EPSD	COSMIC	0.942	Down-regulation
AGC_PKC_PKCa_PRKCB_ST	Q06124	PTPN11	P05771-2	PRKCB	S503	Q510P	510	Missense	distal	7	no	3.497	3.684	EPSD	COSMIC	0.942	Up-regulation
AGC_PKC_PKCa_PRKCB_ST	Q06124	PTPN11	P05771-2	PRKCB	S503	G507W	507	Missense	distal	4	no	3.497	3.111	EPSD	COSMIC	0.942	Down-regulation
AGC_PKC_PKCa_PRKCB_ST	Q06124	PTPN11	P05771-2	PRKCB	S503	Q510E	510	Missense	distal	7	no	3.497	3.553	EPSD	COSMIC	0.942	Up-regulation
AGC_PKC_PKCa_PRKCB_ST	Q06124	PTPN11	P05771-2	PRKCB	S503	S506T	506	Missense	distal	3	no	3.497	3.677	EPSD	COSMIC	0.942	Up-regulation
AGC_PKC_PKCa_PRKCB_ST	Q06124	PTPN11	P05771-2	PRKCB	S503	S506A	506	Missense	distal	3	no	3.497	3.283	EPSD	COSMIC	0.942	Down-regulation
AGC_PKC_PKCa_PRKCB_ST	Q06124	PTPN11	P05771-2	PRKCB	S503	R502L	502	Missense	proximal	-1	no	3.497	2.885	EPSD	COSMIC	0.942	Down-regulation
AGC_PKC_PKCa_PRKCB_ST	Q06124	PTPN11	P05771-2	PRKCB	S503	T497I	497	Missense	distal	-6	no	3.497	3.387	EPSD	COSMIC	0.942	Down-regulation
AGC_PKC_PKCa_PRKCB_ST	Q06124	PTPN11	P05771-2	PRKCB	S503	M508I	508	Missense	distal	5	no	3.497	3.616	EPSD	COSMIC	0.942	Up-regulation
AGC_PKC_PKCa_PRKCB_ST	Q06124	PTPN11	P05771-2	PRKCB	S503	G507L	507	Missense	distal	4	no	3.497	3.548	EPSD	COSMIC	0.942	Up-regulation
AGC_PKC_PKCa_PRKCB_ST	Q06124	PTPN11	P05771-2	PRKCB	S503	S503F	503	Missense	central	0	yes	3.497	0.000	EPSD	COSMIC	0.942	Loss
AGC_PKC_PKCa_PRKCB_ST	Q06124	PTPN11	P05771-2	PRKCB	S539	E545K	545	Missense	distal	6	no	3.045	3.542	EPSD	COSMIC	0.942	Up-regulation
AGC_PKC_PKCa_PRKCB_ST	Q06124	PTPN11	P05771-2	PRKCB	S539	E545D	545	Missense	distal	6	no	3.045	2.645	EPSD	COSMIC	0.942	Down-regulation
AGC_PKC_PKCa_PRKCB_ST	Q06124	PTPN11	P05771-2	PRKCB	S539	I533V	533	Missense	distal	-6	no	3.045	3.081	EPSD	COSMIC	0.942	Up-regulation
AGC_PKC_PKCa_PRKCB_ST	Q06124	PTPN11	P05771-2	PRKCB	S539	Y546C	546	Missense	distal	7	no	3.045	3.128	EPSD	COSMIC	0.942	Up-regulation
AGC_PKC_PKCa_PRKCB_ST	Q06124	PTPN11	P05771-2	PRKCB	S539	G543E	543	Missense	distal	4	no	3.045	3.696	EPSD	COSMIC	0.942	Up-regulation
AGC_PKC_PKCa_PRKCB_ST	Q06124	PTPN11	P05771-2	PRKCB	S580	D579E	579	Missense	proximal	-1	no	9.230	9.316	EPSD	COSMIC	0.942	Up-regulation
AGC_PKC_PKCa_PRKCB_ST	Q06124	PTPN11	P05771-2	PRKCB	S580	R582G	582	Missense	proximal	2	no	9.230	0.496	EPSD	COSMIC	0.942	Loss
AGC_PKC_PKCa_PRKCB_ST	Q06124	PTPN11	P05771-2	PRKCB	S580	V583A	583	Missense	distal	3	no	9.230	9.385	EPSD	COSMIC	0.942	Up-regulation
AGC_PKC_PKCa_PRKCB_ST	Q06124	PTPN11	P05771-2	PRKCB	S580	V587A	587	Missense	distal	7	no	9.230	9.285	EPSD	COSMIC	0.942	Up-regulation
AGC_PKC_PKCa_PRKCB_ST	Q06124	PTPN11	P05771-2	PRKCB	S580	S580I	580	Missense	central	0	yes	9.230	0.000	EPSD	COSMIC	0.942	Loss
AGC_PKC_PKCa_PRKCB_ST	Q06124	PTPN11	P05771-2	PRKCB	S595	Q592H	592	Missense	distal	-3	no	7.313	7.525	EPSD	COSMIC	0.942	Up-regulation
AGC_PKC_PKCa_PRKCB_ST	Q06124	PTPN11	P05771-2	PRKCB	S595	K594R	594	Missense	proximal	-1	no	7.313	7.489	EPSD	COSMIC	0.942	Up-regulation
AGC_PKC_PKCa_PRKCB_ST	P49841	GSK3B	P05771-2	PRKCB	S2	S9F	9	Missense	distal	7	no	3.927	3.985	EPSD	COSMIC	0.942	Up-regulation
AGC_PKC_PKCa_PRKCB_ST	P49841	GSK3B	P05771-2	PRKCB	S2	S2P	2	Missense	central	0	yes	3.927	0.000	EPSD	COSMIC	0.942	Loss
AGC_PKC_PKCa_PRKCB_ST	P49841	GSK3B	P05771-2	PRKCB	S9	S9F	9	Missense	central	0	yes	2.332	0.000	PhosphoSitePlus	COSMIC	0.942	Loss
AGC_PKC_PKCa_PRKCB_ST	P49841	GSK3B	P05771-2	PRKCB	S9	P16A	16	Missense	distal	7	no	2.332	2.356	PhosphoSitePlus	COSMIC	0.942	Up-regulation
AGC_PKC_PKCa_PRKCB_ST	P49841	GSK3B	P05771-2	PRKCB	S9	S2P	2	Missense	distal	-7	no	2.332	2.457	PhosphoSitePlus	COSMIC	0.942	Up-regulation
AGC_PKC_PKCa_PRKCB_ST	P49841	GSK3B	P05771-2	PRKCB	S13	S9F	9	Missense	distal	-4	no	1.665	1.643	EPSD	COSMIC	0.942	Down-regulation
AGC_PKC_PKCa_PRKCB_ST	P49841	GSK3B	P05771-2	PRKCB	S13	P16A	16	Missense	distal	3	no	1.665	1.385	EPSD	COSMIC	0.942	Down-regulation
AGC_PKC_PKCa_PRKCB_ST	P49841	GSK3B	P05771-2	PRKCB	S25	A22T	22	Missense	distal	-3	no	0.733	2.179	EPSD	COSMIC	0.942	Gain
AGC_PKC_PKCa_PRKCB_ST	P49841	GSK3B	P05771-2	PRKCB	S29	S35R	35	Missense	distal	6	no	0.028	0.998	EPSD	COSMIC	0.942	Gain
AGC_PKC_PKCa_PRKCB_ST	P49841	GSK3B	P05771-2	PRKCB	S35	D31Y	31	Missense	distal	-4	no	2.853	2.734	EPSD	COSMIC	0.942	Down-regulation
AGC_PKC_PKCa_PRKCB_ST	P49841	GSK3B	P05771-2	PRKCB	S35	D33N	33	Missense	proximal	-2	no	2.853	3.378	EPSD	COSMIC	0.942	Up-regulation
AGC_PKC_PKCa_PRKCB_ST	P49841	GSK3B	P05771-2	PRKCB	S35	S35R	35	Missense	central	0	yes	2.853	0.000	EPSD	COSMIC	0.942	Loss
AGC_PKC_PKCa_PRKCB_ST	P49841	GSK3B	P05771-2	PRKCB	S35	V41G	41	Missense	distal	6	no	2.853	2.679	EPSD	COSMIC	0.942	Down-regulation
AGC_PKC_PKCa_PRKCB_ST	P49841	GSK3B	P05771-2	PRKCB	S35	V37G	37	Missense	proximal	2	no	2.853	-0.578	EPSD	COSMIC	0.942	Loss
AGC_PKC_PKCa_PRKCB_ST	P49841	GSK3B	P05771-2	PRKCB	S35	D33G	33	Missense	proximal	-2	no	2.853	3.233	EPSD	COSMIC;GDSC;CCLE	0.942	Up-regulation
AGC_PKC_PKCa_PRKCB_ST	P49841	GSK3B	P05771-2	PRKCB	S35	D33H	33	Missense	proximal	-2	no	2.853	3.085	EPSD	COSMIC	0.942	Up-regulation
AGC_PKC_PKCa_PRKCB_ST	P49841	GSK3B	P05771-2	PRKCB	S203	Q206K	206	Missense	distal	3	no	2.951	3.059	EPSD	COSMIC	0.942	Up-regulation
AGC_PKC_PKCa_PRKCB_ST	P49841	GSK3B	P05771-2	PRKCB	S203	L196V	196	Missense	distal	-7	no	2.951	2.964	EPSD	COSMIC	0.942	Up-regulation
AGC_PKC_PKCa_PRKCB_ST	P35579	MYH9	P05771-2	PRKCB	S197	V194M	194	Missense	distal	-3	no	3.845	3.058	EPSD	COSMIC	0.942	Down-regulation
AGC_PKC_PKCa_PRKCB_ST	P35579	MYH9	P05771-2	PRKCB	S197	A195T	195	Missense	proximal	-2	no	3.845	4.250	EPSD	COSMIC	0.942	Up-regulation
AGC_PKC_PKCa_PRKCB_ST	P35579	MYH9	P05771-2	PRKCB	S541	M547V	547	Missense	distal	6	no	1.313	0.996	EPSD	COSMIC;CCLE	0.942	Down-regulation
AGC_PKC_PKCa_PRKCB_ST	P35579	MYH9	P05771-2	PRKCB	S541	K545N	545	Missense	distal	4	no	1.313	0.737	EPSD	COSMIC	0.942	Loss
AGC_PKC_PKCa_PRKCB_ST	P35579	MYH9	P05771-2	PRKCB	S541	D539N	539	Missense	proximal	-2	no	1.313	1.838	EPSD	COSMIC	0.942	Up-regulation
AGC_PKC_PKCa_PRKCB_ST	P35579	MYH9	P05771-2	PRKCB	T725	L724V	724	Missense	proximal	-1	no	1.022	1.162	EPSD	COSMIC	0.942	Up-regulation
AGC_PKC_PKCa_PRKCB_ST	P35579	MYH9	P05771-2	PRKCB	T725	S728F	728	Missense	distal	3	no	1.022	0.759	EPSD	COSMIC	0.942	Loss
AGC_PKC_PKCa_PRKCB_ST	P35579	MYH9	P05771-2	PRKCB	S957	A958T	958	Missense	proximal	1	no	4.481	4.035	EPSD	COSMIC	0.942	Down-regulation
AGC_PKC_PKCa_PRKCB_ST	P35579	MYH9	P05771-2	PRKCB	S1122	S1126F	1126	Missense	distal	4	no	1.709	1.560	EPSD	COSMIC	0.942	Down-regulation
AGC_PKC_PKCa_PRKCB_ST	P35579	MYH9	P05771-2	PRKCB	S1122	L1116P	1116	Missense	distal	-6	no	1.709	1.694	EPSD	COSMIC	0.942	Down-regulation
AGC_PKC_PKCa_PRKCB_ST	P35579	MYH9	P05771-2	PRKCB	T1208	E1203K	1203	Missense	distal	-5	no	2.263	2.336	EPSD	COSMIC	0.942	Up-regulation
AGC_PKC_PKCa_PRKCB_ST	P35579	MYH9	P05771-2	PRKCB	T1208	A1202V	1202	Missense	distal	-6	no	2.263	2.329	EPSD	COSMIC	0.942	Up-regulation
AGC_PKC_PKCa_PRKCB_ST	P35579	MYH9	P05771-2	PRKCB	S1340	D1336N	1336	Missense	distal	-4	no	6.141	6.133	EPSD	COSMIC	0.942	Down-regulation
AGC_PKC_PKCa_PRKCB_ST	P35579	MYH9	P05771-2	PRKCB	S1340	S1340F	1340	Missense	central	0	yes	6.141	0.000	EPSD	COSMIC;GDSC;CCLE	0.942	Loss
AGC_PKC_PKCa_PRKCB_ST	P35579	MYH9	P05771-2	PRKCB	S1340	R1342Q	1342	Missense	proximal	2	no	6.141	-0.408	EPSD	COSMIC;CCLE	0.942	Loss
AGC_PKC_PKCa_PRKCB_ST	P35579	MYH9	P05771-2	PRKCB	S1480	A1484V	1484	Missense	distal	4	no	0.806	1.358	EPSD	COSMIC	0.942	Gain
AGC_PKC_PKCa_PRKCB_ST	P35579	MYH9	P05771-2	PRKCB	S1480	A1484T	1484	Missense	distal	4	no	0.806	1.249	EPSD	COSMIC	0.942	Gain
AGC_PKC_PKCa_PRKCB_ST	P35579	MYH9	P05771-2	PRKCB	S1511	L1509R	1509	Missense	proximal	-2	no	0.299	2.819	EPSD	COSMIC	0.942	Gain
AGC_PKC_PKCa_PRKCB_ST	P35579	MYH9	P05771-2	PRKCB	S1526	R1528W	1528	Missense	proximal	2	no	1.959	-7.554	EPSD	COSMIC	0.942	Loss
AGC_PKC_PKCa_PRKCB_ST	P35579	MYH9	P05771-2	PRKCB	S1892	R1893C	1893	Missense	proximal	1	no	3.035	0.398	EPSD	COSMIC	0.942	Loss
AGC_PKC_PKCa_PRKCB_ST	Q9UBS0	RPS6KB2	P05771-2	PRKCB	T228	A224T	224	Missense	distal	-4	no	1.590	1.486	EPSD	COSMIC	0.942	Down-regulation
AGC_PKC_PKCa_PRKCB_ST	Q9UBS0	RPS6KB2	P05771-2	PRKCB	T228	V225F	225	Missense	distal	-3	no	1.590	0.622	EPSD	COSMIC	0.942	Loss
AGC_PKC_PKCa_PRKCB_ST	Q9UBS0	RPS6KB2	P05771-2	PRKCB	S410	R413C	413	Missense	distal	3	no	7.610	6.757	EPSD	COSMIC	0.942	Down-regulation
AGC_PKC_PKCa_PRKCB_ST	Q9UBS0	RPS6KB2	P05771-2	PRKCB	S410	R413H	413	Missense	distal	3	no	7.610	6.805	EPSD	COSMIC	0.942	Down-regulation
AGC_PKC_PKCa_PRKCB_ST	Q9UBS0	RPS6KB2	P05771-2	PRKCB	S417	P421S	421	Missense	distal	4	no	1.767	1.633	EPSD	COSMIC	0.942	Down-regulation
AGC_PKC_PKCa_PRKCB_ST	Q9UBS0	RPS6KB2	P05771-2	PRKCB	S417	R413C	413	Missense	distal	-4	no	1.767	2.273	EPSD	COSMIC	0.942	Up-regulation
AGC_PKC_PKCa_PRKCB_ST	Q9UBS0	RPS6KB2	P05771-2	PRKCB	S417	R413H	413	Missense	distal	-4	no	1.767	2.074	EPSD	COSMIC	0.942	Up-regulation
AGC_PKC_PKCa_PRKCB_ST	Q9UBS0	RPS6KB2	P05771-2	PRKCB	S417	P421L	421	Missense	distal	4	no	1.767	1.345	EPSD	COSMIC	0.942	Down-regulation
AGC_PKC_PKCa_PRKCB_ST	Q9UBS0	RPS6KB2	P05771-2	PRKCB	S417	P424L	424	Missense	distal	7	no	1.767	1.735	EPSD	COSMIC	0.942	Down-regulation
AGC_PKC_PKCa_PRKCB_ST	Q9UBS0	RPS6KB2	P05771-2	PRKCB	S436	T443M	443	Missense	distal	7	no	0.912	0.944	EPSD	COSMIC	0.942	Gain
AGC_PKC_PKCa_PRKCB_ST	Q9UBS0	RPS6KB2	P05771-2	PRKCB	S468	S468P	468	Missense	central	0	yes	3.257	0.000	EPSD	COSMIC	0.942	Loss
AGC_PKC_PKCa_PRKCB_ST	Q9UBS0	RPS6KB2	P05771-2	PRKCB	S468	P463S	463	Missense	distal	-5	no	3.257	3.282	EPSD	COSMIC	0.942	Up-regulation
AGC_PKC_PKCa_PRKCB_ST	Q9UBS0	RPS6KB2	P05771-2	PRKCB	S468	R475G	475	Missense	distal	7	no	3.257	3.557	EPSD	COSMIC	0.942	Up-regulation
AGC_PKC_PKCa_PRKCB_ST	Q9UBS0	RPS6KB2	P05771-2	PRKCB	S468	P467H	467	Missense	proximal	-1	no	3.257	3.438	EPSD	COSMIC	0.942	Up-regulation
AGC_PKC_PKCa_PRKCB_ST	Q9UBS0	RPS6KB2	P05771-2	PRKCB	S468	R465H	465	Missense	distal	-3	no	3.257	0.270	EPSD	COSMIC	0.942	Loss
AGC_PKC_PKCa_PRKCB_ST	Q9UBS0	RPS6KB2	P05771-2	PRKCB	T470	S468P	468	Missense	proximal	-2	no	1.712	1.833	EPSD	COSMIC	0.942	Up-regulation
AGC_PKC_PKCa_PRKCB_ST	Q9UBS0	RPS6KB2	P05771-2	PRKCB	T470	P463S	463	Missense	distal	-7	no	1.712	1.587	EPSD	COSMIC	0.942	Down-regulation
AGC_PKC_PKCa_PRKCB_ST	Q9UBS0	RPS6KB2	P05771-2	PRKCB	T470	R477H	477	Missense	distal	7	no	1.712	1.938	EPSD	COSMIC	0.942	Up-regulation
AGC_PKC_PKCa_PRKCB_ST	Q9UBS0	RPS6KB2	P05771-2	PRKCB	T470	R475G	475	Missense	distal	5	no	1.712	1.283	EPSD	COSMIC	0.942	Down-regulation
AGC_PKC_PKCa_PRKCB_ST	Q9UBS0	RPS6KB2	P05771-2	PRKCB	T470	P467H	467	Missense	distal	-3	no	1.712	1.938	EPSD	COSMIC	0.942	Up-regulation
AGC_PKC_PKCa_PRKCB_ST	Q9UBS0	RPS6KB2	P05771-2	PRKCB	T470	R465H	465	Missense	distal	-5	no	1.712	1.465	EPSD	COSMIC	0.942	Down-regulation
AGC_PKC_PKCa_PRKCB_ST	Q9UBS0	RPS6KB2	P05771-2	PRKCB	S473	R479H	479	Missense	distal	6	no	10.091	9.331	PhosphoSitePlus	COSMIC;CCLE	0.942	Down-regulation
AGC_PKC_PKCa_PRKCB_ST	Q9UBS0	RPS6KB2	P05771-2	PRKCB	S473	S468P	468	Missense	distal	-5	no	10.091	10.065	PhosphoSitePlus	COSMIC	0.942	Down-regulation
AGC_PKC_PKCa_PRKCB_ST	Q9UBS0	RPS6KB2	P05771-2	PRKCB	S473	P480Q	480	Missense	distal	7	no	10.091	9.904	PhosphoSitePlus	COSMIC	0.942	Down-regulation
AGC_PKC_PKCa_PRKCB_ST	Q9UBS0	RPS6KB2	P05771-2	PRKCB	S473	R477H	477	Missense	distal	4	no	10.091	9.269	PhosphoSitePlus	COSMIC	0.942	Down-regulation
AGC_PKC_PKCa_PRKCB_ST	Q9UBS0	RPS6KB2	P05771-2	PRKCB	S473	R475G	475	Missense	proximal	2	no	10.091	1.357	PhosphoSitePlus	COSMIC	0.942	Down-regulation
AGC_PKC_PKCa_PRKCB_ST	Q9UBS0	RPS6KB2	P05771-2	PRKCB	S473	P467H	467	Missense	distal	-6	no	10.091	10.173	PhosphoSitePlus	COSMIC	0.942	Up-regulation
AGC_PKC_PKCa_PRKCB_ST	Q9H1D0	TRPV6	P05771-2	PRKCB	S182	R179H	179	Missense	distal	-3	no	3.656	0.670	EPSD	COSMIC	0.942	Loss
AGC_PKC_PKCa_PRKCB_ST	Q9H1D0	TRPV6	P05771-2	PRKCB	S182	R179C	179	Missense	distal	-3	no	3.656	-0.243	EPSD	COSMIC	0.942	Loss
AGC_PKC_PKCa_PRKCB_ST	Q9H1D0	TRPV6	P05771-2	PRKCB	S182	G189V	189	Missense	distal	7	no	3.656	3.588	EPSD	COSMIC	0.942	Down-regulation
AGC_PKC_PKCa_PRKCB_ST	Q9H1D0	TRPV6	P05771-2	PRKCB	S182	A185S	185	Missense	distal	3	no	3.656	3.870	EPSD	COSMIC	0.942	Up-regulation
AGC_PKC_PKCa_PRKCB_ST	Q9H1D0	TRPV6	P05771-2	PRKCB	S182	A187D	187	Missense	distal	5	no	3.656	3.745	EPSD	COSMIC	0.942	Up-regulation
AGC_PKC_PKCa_PRKCB_ST	Q9H1D0	TRPV6	P05771-2	PRKCB	S184	R179H	179	Missense	distal	-5	no	3.920	3.673	PhosphoSitePlus;EPSD	COSMIC	0.942	Down-regulation
AGC_PKC_PKCa_PRKCB_ST	Q9H1D0	TRPV6	P05771-2	PRKCB	S184	R179C	179	Missense	distal	-5	no	3.920	3.687	PhosphoSitePlus;EPSD	COSMIC	0.942	Down-regulation
AGC_PKC_PKCa_PRKCB_ST	Q9H1D0	TRPV6	P05771-2	PRKCB	S184	G189V	189	Missense	distal	5	no	3.920	3.937	PhosphoSitePlus;EPSD	COSMIC	0.942	Up-regulation
AGC_PKC_PKCa_PRKCB_ST	Q9H1D0	TRPV6	P05771-2	PRKCB	S184	A185S	185	Missense	proximal	1	no	3.920	3.310	PhosphoSitePlus;EPSD	COSMIC	0.942	Down-regulation
AGC_PKC_PKCa_PRKCB_ST	Q9H1D0	TRPV6	P05771-2	PRKCB	S184	A187D	187	Missense	distal	3	no	3.920	4.241	PhosphoSitePlus;EPSD	COSMIC	0.942	Up-regulation
AGC_PKC_PKCa_PRKCB_ST	Q9H1D0	TRPV6	P05771-2	PRKCB	S401	P402R	402	Missense	proximal	1	no	6.006	7.826	EPSD	COSMIC	0.942	Up-regulation
AGC_PKC_PKCa_PRKCB_ST	Q9H1D0	TRPV6	P05771-2	PRKCB	S401	R403Q	403	Missense	proximal	2	no	6.006	-0.543	EPSD	COSMIC	0.942	Loss
AGC_PKC_PKCa_PRKCB_ST	Q9H1D0	TRPV6	P05771-2	PRKCB	S401	L407I	407	Missense	distal	6	no	6.006	6.129	EPSD	COSMIC	0.942	Up-regulation
AGC_PKC_PKCa_PRKCB_ST	Q9H1D0	TRPV6	P05771-2	PRKCB	S401	R399H	399	Missense	proximal	-2	no	6.006	3.991	EPSD	COSMIC	0.942	Down-regulation
AGC_PKC_PKCa_PRKCB_ST	Q9H1D0	TRPV6	P05771-2	PRKCB	S401	R395W	395	Missense	distal	-6	no	6.006	5.561	EPSD	COSMIC	0.942	Down-regulation
AGC_PKC_PKCa_PRKCB_ST	Q9H1D0	TRPV6	P05771-2	PRKCB	S401	R399S	399	Missense	proximal	-2	no	6.006	4.053	EPSD	COSMIC	0.942	Down-regulation
AGC_PKC_PKCa_PRKCB_ST	Q9H1D0	TRPV6	P05771-2	PRKCB	S401	L407V	407	Missense	distal	6	no	6.006	6.011	EPSD	COSMIC	0.942	Up-regulation
AGC_PKC_PKCa_PRKCB_ST	Q9H1D0	TRPV6	P05771-2	PRKCB	S401	D404G	404	Missense	distal	3	no	6.006	5.636	EPSD	COSMIC	0.942	Down-regulation
AGC_PKC_PKCa_PRKCB_ST	Q9H1D0	TRPV6	P05771-2	PRKCB	S401	R403W	403	Missense	proximal	2	no	6.006	-3.508	EPSD	COSMIC	0.942	Loss
AGC_PKC_PKCa_PRKCB_ST	Q9H1D0	TRPV6	P05771-2	PRKCB	S401	S401R	401	Missense	central	0	yes	6.006	0.000	EPSD	COSMIC	0.942	Loss
AGC_PKC_PKCa_PRKCB_ST	Q9H1D0	TRPV6	P05771-2	PRKCB	T728	M721T	721	Missense	distal	-7	no	1.962	1.796	EPSD;PhosphoSitePlus	COSMIC	0.942	Down-regulation
AGC_PKC_PKCa_PRKCB_ST	Q9H1D0	TRPV6	P05771-2	PRKCB	T728	R730C	730	Missense	proximal	2	no	1.962	-2.531	EPSD;PhosphoSitePlus	COSMIC	0.942	Loss
AGC_PKC_PKCa_PRKCB_ST	Q9H1D0	TRPV6	P05771-2	PRKCB	T728	R726Q	726	Missense	proximal	-2	no	1.962	0.990	EPSD;PhosphoSitePlus	COSMIC	0.942	Down-regulation
AGC_PKC_PKCa_PRKCB_ST	Q9H1D0	TRPV6	P05771-2	PRKCB	T728	M721I	721	Missense	distal	-7	no	1.962	1.692	EPSD;PhosphoSitePlus	COSMIC	0.942	Down-regulation
AGC_PKC_PKCa_PRKCB_ST	Q9H1D0	TRPV6	P05771-2	PRKCB	T728	S729T	729	Missense	proximal	1	no	1.962	2.126	EPSD;PhosphoSitePlus	COSMIC	0.942	Up-regulation
AGC_PKC_PKCa_PRKCB_ST	Q9H1D0	TRPV6	P05771-2	PRKCB	T728	S729Y	729	Missense	proximal	1	no	1.962	3.174	EPSD;PhosphoSitePlus	COSMIC	0.942	Up-regulation
AGC_PKC_PKCa_PRKCB_ST	Q9H1D0	TRPV6	P05771-2	PRKCB	T728	S723L	723	Missense	distal	-5	no	1.962	1.955	EPSD;PhosphoSitePlus	COSMIC	0.942	Down-regulation
AGC_PKC_PKCa_PRKCB_ST	Q9H1D0	TRPV6	P05771-2	PRKCB	T728	W735L	735	Missense	distal	7	no	1.962	1.891	EPSD;PhosphoSitePlus	COSMIC	0.942	Down-regulation
AGC_PKC_PKCa_PRKCB_ST	Q9H1D0	TRPV6	P05771-2	PRKCB	T742	R744S	744	Missense	proximal	2	no	8.532	2.535	EPSD	COSMIC	0.942	Down-regulation
AGC_PKC_PKCa_PRKCB_ST	Q9H1D0	TRPV6	P05771-2	PRKCB	T742	R748C	748	Missense	distal	6	no	8.532	7.337	EPSD	COSMIC	0.942	Down-regulation
AGC_PKC_PKCa_PRKCB_ST	Q9H1D0	TRPV6	P05771-2	PRKCB	T742	R748H	748	Missense	distal	6	no	8.532	7.772	EPSD	COSMIC	0.942	Down-regulation
AGC_PKC_PKCa_PRKCB_ST	Q9H1D0	TRPV6	P05771-2	PRKCB	T742	R739P	739	Missense	distal	-3	no	8.532	5.319	EPSD	COSMIC	0.942	Down-regulation
AGC_PKC_PKCa_PRKCB_ST	Q9H1D0	TRPV6	P05771-2	PRKCB	T742	R739W	739	Missense	distal	-3	no	8.532	3.039	EPSD	COSMIC	0.942	Down-regulation
AGC_PKC_PKCa_PRKCB_ST	Q9H1D0	TRPV6	P05771-2	PRKCB	T742	R739Q	739	Missense	distal	-3	no	8.532	5.333	EPSD	COSMIC	0.942	Down-regulation
AGC_PKC_PKCa_PRKCB_ST	Q9H1D0	TRPV6	P05771-2	PRKCB	T742	G741R	741	Missense	proximal	-1	no	8.532	9.064	EPSD	COSMIC	0.942	Up-regulation
AGC_PKC_PKCa_PRKCB_ST	Q9H1D0	TRPV6	P05771-2	PRKCB	T742	R745S	745	Missense	distal	3	no	8.532	7.766	EPSD	COSMIC	0.942	Down-regulation
AGC_PKC_PKCa_PRKCB_ST	Q9H1D0	TRPV6	P05771-2	PRKCB	T742	G749R	749	Missense	distal	7	no	8.532	8.231	EPSD	COSMIC	0.942	Down-regulation
AGC_PKC_PKCa_PRKCB_ST	Q9H1D0	TRPV6	P05771-2	PRKCB	T742	W735L	735	Missense	distal	-7	no	8.532	8.374	EPSD	COSMIC	0.942	Down-regulation
AGC_PKC_PKCa_PRKCB_ST	P21730	C5AR1	P05771-2	PRKCB	S327	E331K	331	Missense	distal	4	no	1.648	2.239	EPSD	COSMIC	0.942	Up-regulation
AGC_PKC_PKCa_PRKCB_ST	P21730	C5AR1	P05771-2	PRKCB	S332	E331K	331	Missense	proximal	-1	no	1.111	1.254	EPSD	COSMIC	0.942	Up-regulation
AGC_PKC_PKCa_PRKCB_ST	P21730	C5AR1	P05771-2	PRKCB	S332	T336M	336	Missense	distal	4	no	1.111	1.170	EPSD	COSMIC	0.942	Up-regulation
AGC_PKC_PKCa_PRKCB_ST	P21730	C5AR1	P05771-2	PRKCB	S334	E331K	331	Missense	distal	-3	no	0.990	4.325	PhosphoSitePlus	COSMIC	0.942	Up-regulation
AGC_PKC_PKCa_PRKCB_ST	P21730	C5AR1	P05771-2	PRKCB	S334	T336M	336	Missense	proximal	2	no	0.990	-1.128	PhosphoSitePlus	COSMIC	0.942	Loss
AGC_PKC_PKCa_PRKCB_ST	P14598	NCF1	P05771-2	PRKCB	T356	P349R	349	Missense	distal	-7	no	4.947	4.551	EPSD	COSMIC	0.942	Down-regulation
AGC_PKC_PKCa_PRKCB_ST	Q14152	EIF3A	P05771-2	PRKCB	S108	I115M	115	Missense	distal	7	no	1.189	1.248	EPSD	COSMIC	0.942	Up-regulation
AGC_PKC_PKCa_PRKCB_ST	Q14152	EIF3A	P05771-2	PRKCB	S263	P267H	267	Missense	distal	4	no	1.904	1.965	EPSD	COSMIC	0.942	Up-regulation
AGC_PKC_PKCa_PRKCB_ST	Q14152	EIF3A	P05771-2	PRKCB	S263	I256V	256	Missense	distal	-7	no	1.904	2.073	EPSD	COSMIC	0.942	Up-regulation
AGC_PKC_PKCa_PRKCB_ST	Q14152	EIF3A	P05771-2	PRKCB	S319	D313Y	313	Missense	distal	-6	no	3.351	3.339	EPSD	COSMIC	0.942	Down-regulation
AGC_PKC_PKCa_PRKCB_ST	Q14152	EIF3A	P05771-2	PRKCB	S319	M315T	315	Missense	distal	-4	no	3.351	3.314	EPSD	COSMIC	0.942	Down-regulation
AGC_PKC_PKCa_PRKCB_ST	Q14152	EIF3A	P05771-2	PRKCB	S584	R581C	581	Missense	distal	-3	no	1.203	-2.697	EPSD	COSMIC	0.942	Loss
AGC_PKC_PKCa_PRKCB_ST	Q14152	EIF3A	P05771-2	PRKCB	S584	R589C	589	Missense	distal	5	no	1.203	0.759	EPSD	COSMIC;GDSC;CCLE	0.942	Loss
AGC_PKC_PKCa_PRKCB_ST	Q14152	EIF3A	P05771-2	PRKCB	T635	K632N	632	Missense	distal	-3	no	6.625	3.464	EPSD	COSMIC	0.942	Down-regulation
AGC_PKC_PKCa_PRKCB_ST	Q14152	EIF3A	P05771-2	PRKCB	T635	R639H	639	Missense	distal	4	no	6.625	5.803	EPSD	COSMIC	0.942	Down-regulation
AGC_PKC_PKCa_PRKCB_ST	Q14152	EIF3A	P05771-2	PRKCB	S978	R980C	980	Missense	proximal	2	no	3.884	-0.609	EPSD	COSMIC;GDSC;CCLE	0.942	Loss
AGC_PKC_PKCa_PRKCB_ST	Q14152	EIF3A	P05771-2	PRKCB	S978	D984N	984	Missense	distal	6	no	3.884	4.152	EPSD	COSMIC;GDSC	0.942	Up-regulation
AGC_PKC_PKCa_PRKCB_ST	Q14152	EIF3A	P05771-2	PRKCB	S978	G971A	971	Missense	distal	-7	no	3.884	3.773	EPSD	COSMIC	0.942	Down-regulation
AGC_PKC_PKCa_PRKCB_ST	Q14152	EIF3A	P05771-2	PRKCB	S978	R980H	980	Missense	proximal	2	no	3.884	-2.477	EPSD	COSMIC	0.942	Loss
AGC_PKC_PKCa_PRKCB_ST	Q14152	EIF3A	P05771-2	PRKCB	S978	D985G	985	Missense	distal	7	no	3.884	4.111	EPSD	COSMIC	0.942	Up-regulation
AGC_PKC_PKCa_PRKCB_ST	Q14152	EIF3A	P05771-2	PRKCB	S988	D984N	984	Missense	distal	-4	no	3.944	3.936	EPSD	COSMIC;GDSC	0.942	Down-regulation
AGC_PKC_PKCa_PRKCB_ST	Q14152	EIF3A	P05771-2	PRKCB	S988	D985G	985	Missense	distal	-3	no	3.944	3.627	EPSD	COSMIC	0.942	Down-regulation
AGC_PKC_PKCa_PRKCB_ST	Q14152	EIF3A	P05771-2	PRKCB	S988	R986W	986	Missense	proximal	-2	no	3.944	0.668	EPSD	COSMIC	0.942	Loss
AGC_PKC_PKCa_PRKCB_ST	Q14152	EIF3A	P05771-2	PRKCB	S988	R990H	990	Missense	proximal	2	no	3.944	-2.417	EPSD	COSMIC;CCLE	0.942	Loss
AGC_PKC_PKCa_PRKCB_ST	Q14152	EIF3A	P05771-2	PRKCB	S1028	R1030Q	1030	Missense	proximal	2	no	3.070	-3.479	EPSD	COSMIC;GDSC;CCLE	0.942	Loss
AGC_PKC_PKCa_PRKCB_ST	Q14152	EIF3A	P05771-2	PRKCB	S1028	R1026S	1026	Missense	proximal	-2	no	3.070	1.117	EPSD	COSMIC	0.942	Down-regulation
AGC_PKC_PKCa_PRKCB_ST	Q14152	EIF3A	P05771-2	PRKCB	S1059	D1055H	1055	Missense	distal	-4	no	3.998	3.989	EPSD	COSMIC	0.942	Down-regulation
AGC_PKC_PKCa_PRKCB_ST	Q14152	EIF3A	P05771-2	PRKCB	S1059	R1057L	1057	Missense	proximal	-2	no	3.998	1.478	EPSD	COSMIC	0.942	Down-regulation
AGC_PKC_PKCa_PRKCB_ST	Q14152	EIF3A	P05771-2	PRKCB	S1059	A1053V	1053	Missense	distal	-6	no	3.998	4.064	EPSD	COSMIC	0.942	Up-regulation
AGC_PKC_PKCa_PRKCB_ST	Q14152	EIF3A	P05771-2	PRKCB	S1149	M1143T	1143	Missense	distal	-6	no	5.495	5.599	EPSD	COSMIC	0.942	Up-regulation
AGC_PKC_PKCa_PRKCB_ST	Q14152	EIF3A	P05771-2	PRKCB	S1149	M1143I	1143	Missense	distal	-6	no	5.495	5.489	EPSD	COSMIC	0.942	Down-regulation
AGC_PKC_PKCa_PRKCB_ST	Q14152	EIF3A	P05771-2	PRKCB	S1195	S1198L	1198	Missense	distal	3	no	1.857	1.537	EPSD	COSMIC	0.942	Down-regulation
AGC_PKC_PKCa_PRKCB_ST	Q14152	EIF3A	P05771-2	PRKCB	S1262	S1257L	1257	Missense	distal	-5	no	2.811	2.805	EPSD	COSMIC	0.942	Down-regulation
AGC_PKC_PKCa_PRKCB_ST	Q14152	EIF3A	P05771-2	PRKCB	S1262	S1263I	1263	Missense	proximal	1	no	2.811	4.085	EPSD	COSMIC	0.942	Up-regulation
AGC_PKC_PKCa_PRKCB_ST	Q14152	EIF3A	P05771-2	PRKCB	S1262	D1267N	1267	Missense	distal	5	no	2.811	2.688	EPSD	COSMIC	0.942	Down-regulation
AGC_PKC_PKCa_PRKCB_ST	Q14152	EIF3A	P05771-2	PRKCB	S1262	R1268S	1268	Missense	distal	6	no	2.811	1.842	EPSD	COSMIC	0.942	Down-regulation
AGC_PKC_PKCa_PRKCB_ST	Q14152	EIF3A	P05771-2	PRKCB	S1263	S1257L	1257	Missense	distal	-6	no	6.275	6.176	EPSD	COSMIC	0.942	Down-regulation
AGC_PKC_PKCa_PRKCB_ST	Q14152	EIF3A	P05771-2	PRKCB	S1263	S1263I	1263	Missense	central	0	yes	6.275	0.000	EPSD	COSMIC	0.942	Loss
AGC_PKC_PKCa_PRKCB_ST	Q14152	EIF3A	P05771-2	PRKCB	S1263	D1267N	1267	Missense	distal	4	no	6.275	6.527	EPSD	COSMIC	0.942	Up-regulation
AGC_PKC_PKCa_PRKCB_ST	Q14152	EIF3A	P05771-2	PRKCB	S1263	R1268S	1268	Missense	distal	5	no	6.275	5.868	EPSD	COSMIC	0.942	Down-regulation
AGC_PKC_PKCa_PRKCB_ST	Q14152	EIF3A	P05771-2	PRKCB	S1302	R1295Q	1295	Missense	distal	-7	no	2.157	2.182	EPSD	COSMIC	0.942	Up-regulation
AGC_PKC_PKCa_PRKCB_ST	Q14152	EIF3A	P05771-2	PRKCB	S1302	P1299L	1299	Missense	distal	-3	no	2.157	1.213	EPSD	COSMIC	0.942	Down-regulation
AGC_PKC_PKCa_PRKCB_ST	Q14152	EIF3A	P05771-2	PRKCB	S1302	S1308R	1308	Missense	distal	6	no	2.157	3.126	EPSD	COSMIC	0.942	Up-regulation
AGC_PKC_PKCa_PRKCB_ST	Q14152	EIF3A	P05771-2	PRKCB	S1309	A1313T	1313	Missense	distal	4	no	1.871	2.314	EPSD	COSMIC	0.942	Up-regulation
AGC_PKC_PKCa_PRKCB_ST	Q14152	EIF3A	P05771-2	PRKCB	S1309	D1315N	1315	Missense	distal	6	no	1.871	2.139	EPSD	COSMIC	0.942	Up-regulation
AGC_PKC_PKCa_PRKCB_ST	Q14152	EIF3A	P05771-2	PRKCB	S1309	S1308R	1308	Missense	proximal	-1	no	1.871	2.476	EPSD	COSMIC	0.942	Up-regulation
AGC_PKC_PKCa_PRKCB_ST	P20700	LMNB1	P05771-2	PRKCB	S52	E54D	54	Missense	proximal	2	no	1.197	1.590	EPSD	COSMIC	0.942	Up-regulation
AGC_PKC_PKCa_PRKCB_ST	P20700	LMNB1	P05771-2	PRKCB	S200	T202I	202	Missense	proximal	2	no	2.652	2.013	EPSD	COSMIC	0.942	Down-regulation
AGC_PKC_PKCa_PRKCB_ST	P20700	LMNB1	P05771-2	PRKCB	S200	T202S	202	Missense	proximal	2	no	2.652	1.298	EPSD	COSMIC	0.942	Down-regulation
AGC_PKC_PKCa_PRKCB_ST	P20700	LMNB1	P05771-2	PRKCB	T219	Y212H	212	Missense	distal	-7	no	4.447	4.619	EPSD	COSMIC	0.942	Up-regulation
AGC_PKC_PKCa_PRKCB_ST	P20700	LMNB1	P05771-2	PRKCB	S232	S232F	232	Missense	central	0	yes	4.265	0.000	EPSD	COSMIC	0.942	Loss
AGC_PKC_PKCa_PRKCB_ST	P20700	LMNB1	P05771-2	PRKCB	S288	S288N	288	Missense	central	0	yes	3.903	0.000	EPSD	COSMIC;GDSC;CCLE	0.942	Loss
AGC_PKC_PKCa_PRKCB_ST	P20700	LMNB1	P05771-2	PRKCB	S302	E301K	301	Missense	proximal	-1	no	2.387	2.531	EPSD	COSMIC	0.942	Up-regulation
AGC_PKC_PKCa_PRKCB_ST	P20700	LMNB1	P05771-2	PRKCB	S302	N309H	309	Missense	distal	7	no	2.387	2.460	EPSD	COSMIC	0.942	Up-regulation
AGC_PKC_PKCa_PRKCB_ST	P20700	LMNB1	P05771-2	PRKCB	T340	R336C	336	Missense	distal	-4	no	2.010	2.516	EPSD	COSMIC	0.942	Up-regulation
AGC_PKC_PKCa_PRKCB_ST	P20700	LMNB1	P05771-2	PRKCB	T340	R336H	336	Missense	distal	-4	no	2.010	2.316	EPSD	COSMIC	0.942	Up-regulation
AGC_PKC_PKCa_PRKCB_ST	P20700	LMNB1	P05771-2	PRKCB	S395	V398M	398	Missense	distal	3	no	3.812	4.136	EPSD;PhosphoSitePlus	COSMIC	0.942	Up-regulation
AGC_PKC_PKCa_PRKCB_ST	P20700	LMNB1	P05771-2	PRKCB	S405	V409L	409	Missense	distal	4	no	7.169	6.800	PhosphoSitePlus;EPSD	COSMIC	0.942	Down-regulation
AGC_PKC_PKCa_PRKCB_ST	P20700	LMNB1	P05771-2	PRKCB	S405	V398M	398	Missense	distal	-7	no	7.169	7.270	PhosphoSitePlus;EPSD	COSMIC	0.942	Up-regulation
AGC_PKC_PKCa_PRKCB_ST	P20700	LMNB1	P05771-2	PRKCB	S408	V409L	409	Missense	proximal	1	no	1.690	2.043	EPSD	COSMIC	0.942	Up-regulation
AGC_PKC_PKCa_PRKCB_ST	P20700	LMNB1	P05771-2	PRKCB	T411	V409L	409	Missense	proximal	-2	no	2.783	1.844	EPSD	COSMIC	0.942	Down-regulation
AGC_PKC_PKCa_PRKCB_ST	P20700	LMNB1	P05771-2	PRKCB	T575	A578S	578	Missense	distal	3	no	1.841	2.055	EPSD	COSMIC	0.942	Up-regulation
AGC_PKC_PKCa_PRKCB_ST	P20700	LMNB1	P05771-2	PRKCB	S579	A578S	578	Missense	proximal	-1	no	2.788	2.759	EPSD	COSMIC	0.942	Down-regulation
AGC_PKC_PKCa_PRKCB_ST	Q5T7P8	SYT6	P05771-2	PRKCB	S148	M147T	147	Missense	proximal	-1	no	3.643	3.634	EPSD	COSMIC	0.942	Down-regulation
AGC_PKC_PKCa_PRKCB_ST	Q5T7P8	SYT6	P05771-2	PRKCB	S148	Q146L	146	Missense	proximal	-2	no	3.643	2.095	EPSD	COSMIC;CCLE	0.942	Down-regulation
AGC_PKC_PKCa_PRKCB_ST	Q5T7P8	SYT6	P05771-2	PRKCB	S169	H172R	172	Missense	distal	3	no	1.291	2.096	EPSD	COSMIC	0.942	Up-regulation
AGC_PKC_PKCa_PRKCB_ST	Q5T7P8	SYT6	P05771-2	PRKCB	S216	K223R	223	Missense	distal	7	no	2.342	2.231	EPSD	COSMIC	0.942	Down-regulation
AGC_PKC_PKCa_PRKCB_ST	Q5T7P8	SYT6	P05771-2	PRKCB	S216	S216L	216	Missense	central	0	yes	2.342	0.000	EPSD	COSMIC;CCLE	0.942	Loss
AGC_PKC_PKCa_PRKCB_ST	Q5T7P8	SYT6	P05771-2	PRKCB	T283	R284L	284	Missense	proximal	1	no	3.174	2.490	EPSD;PhosphoSitePlus	COSMIC	0.942	Down-regulation
AGC_PKC_PKCa_PRKCB_ST	Q5T7P8	SYT6	P05771-2	PRKCB	T283	K288M	288	Missense	distal	5	no	3.174	2.674	EPSD;PhosphoSitePlus	COSMIC	0.942	Down-regulation
AGC_PKC_PKCa_PRKCB_ST	Q5T7P8	SYT6	P05771-2	PRKCB	T283	L290P	290	Missense	distal	7	no	3.174	3.207	EPSD;PhosphoSitePlus	COSMIC;CCLE	0.942	Up-regulation
AGC_PKC_PKCa_PRKCB_ST	Q5T7P8	SYT6	P05771-2	PRKCB	T417	R411M	411	Missense	distal	-6	no	2.583	2.329	EPSD;PhosphoSitePlus	COSMIC	0.942	Down-regulation
AGC_PKC_PKCa_PRKCB_ST	Q5T7P8	SYT6	P05771-2	PRKCB	T418	R411M	411	Missense	distal	-7	no	5.603	5.980	PhosphoSitePlus;EPSD	COSMIC	0.942	Up-regulation
AGC_PKC_PKCa_PRKCB_ST	Q04637	EIF4G1	P05771-2	PRKCB	S45	Q49E	49	Missense	distal	4	no	1.205	1.119	EPSD	COSMIC	0.942	Down-regulation
AGC_PKC_PKCa_PRKCB_ST	Q04637	EIF4G1	P05771-2	PRKCB	S45	R48S	48	Missense	distal	3	no	1.205	0.439	EPSD	COSMIC	0.942	Loss
AGC_PKC_PKCa_PRKCB_ST	Q04637	EIF4G1	P05771-2	PRKCB	S45	P44S	44	Missense	proximal	-1	no	1.205	1.264	EPSD	COSMIC	0.942	Up-regulation
AGC_PKC_PKCa_PRKCB_ST	Q04637	EIF4G1	P05771-2	PRKCB	T179	E176V	176	Missense	distal	-3	no	2.988	3.877	EPSD	COSMIC	0.942	Up-regulation
AGC_PKC_PKCa_PRKCB_ST	Q04637	EIF4G1	P05771-2	PRKCB	T179	R183Q	183	Missense	distal	4	no	2.988	2.368	EPSD	COSMIC	0.942	Down-regulation
AGC_PKC_PKCa_PRKCB_ST	Q04637	EIF4G1	P05771-2	PRKCB	T179	D184G	184	Missense	distal	5	no	2.988	2.747	EPSD	COSMIC	0.942	Down-regulation
AGC_PKC_PKCa_PRKCB_ST	Q04637	EIF4G1	P05771-2	PRKCB	T179	P185L	185	Missense	distal	6	no	2.988	2.287	EPSD	COSMIC	0.942	Down-regulation
AGC_PKC_PKCa_PRKCB_ST	Q04637	EIF4G1	P05771-2	PRKCB	T179	T179M	179	Missense	central	0	yes	2.988	0.000	EPSD	COSMIC	0.942	Loss
AGC_PKC_PKCa_PRKCB_ST	Q04637	EIF4G1	P05771-2	PRKCB	T179	T179A	179	Missense	central	0	yes	2.988	0.000	EPSD	COSMIC	0.942	Loss
AGC_PKC_PKCa_PRKCB_ST	Q04637	EIF4G1	P05771-2	PRKCB	T179	R177C	177	Missense	proximal	-2	no	2.988	1.522	EPSD	COSMIC	0.942	Down-regulation
AGC_PKC_PKCa_PRKCB_ST	Q04637	EIF4G1	P05771-2	PRKCB	S204	G199D	199	Missense	distal	-5	no	3.028	3.144	EPSD	COSMIC	0.942	Up-regulation
AGC_PKC_PKCa_PRKCB_ST	Q04637	EIF4G1	P05771-2	PRKCB	S204	P208L	208	Missense	distal	4	no	3.028	2.605	EPSD	COSMIC	0.942	Down-regulation
AGC_PKC_PKCa_PRKCB_ST	Q04637	EIF4G1	P05771-2	PRKCB	S204	R201C	201	Missense	distal	-3	no	3.028	-0.871	EPSD	COSMIC	0.942	Loss
AGC_PKC_PKCa_PRKCB_ST	Q04637	EIF4G1	P05771-2	PRKCB	S204	R201H	201	Missense	distal	-3	no	3.028	0.041	EPSD	COSMIC	0.942	Loss
AGC_PKC_PKCa_PRKCB_ST	Q04637	EIF4G1	P05771-2	PRKCB	S204	T211M	211	Missense	distal	7	no	3.028	3.060	EPSD	COSMIC	0.942	Up-regulation
AGC_PKC_PKCa_PRKCB_ST	Q04637	EIF4G1	P05771-2	PRKCB	S679	S679F	679	Missense	central	0	yes	3.579	0.000	EPSD	COSMIC	0.942	Loss
AGC_PKC_PKCa_PRKCB_ST	Q04637	EIF4G1	P05771-2	PRKCB	S679	R675H	675	Missense	distal	-4	no	3.579	3.885	EPSD	COSMIC	0.942	Up-regulation
AGC_PKC_PKCa_PRKCB_ST	Q04637	EIF4G1	P05771-2	PRKCB	S679	G686D	686	Missense	distal	7	no	3.579	3.352	EPSD	COSMIC	0.942	Down-regulation
AGC_PKC_PKCa_PRKCB_ST	Q04637	EIF4G1	P05771-2	PRKCB	S679	R681H	681	Missense	proximal	2	no	3.579	-2.783	EPSD	COSMIC	0.942	Loss
AGC_PKC_PKCa_PRKCB_ST	Q04637	EIF4G1	P05771-2	PRKCB	S679	R675Q	675	Missense	distal	-4	no	3.579	3.700	EPSD	COSMIC	0.942	Up-regulation
AGC_PKC_PKCa_PRKCB_ST	Q04637	EIF4G1	P05771-2	PRKCB	S679	R681Q	681	Missense	proximal	2	no	3.579	-2.970	EPSD	COSMIC	0.942	Loss
AGC_PKC_PKCa_PRKCB_ST	Q04637	EIF4G1	P05771-2	PRKCB	S704	G698D	698	Missense	distal	-6	no	1.631	1.801	EPSD	COSMIC	0.942	Up-regulation
AGC_PKC_PKCa_PRKCB_ST	Q04637	EIF4G1	P05771-2	PRKCB	S704	A697V	697	Missense	distal	-7	no	1.631	1.668	EPSD	COSMIC	0.942	Up-regulation
AGC_PKC_PKCa_PRKCB_ST	Q04637	EIF4G1	P05771-2	PRKCB	S704	A697S	697	Missense	distal	-7	no	1.631	1.662	EPSD	COSMIC	0.942	Up-regulation
AGC_PKC_PKCa_PRKCB_ST	Q04637	EIF4G1	P05771-2	PRKCB	S704	L699M	699	Missense	distal	-5	no	1.631	1.640	EPSD	COSMIC	0.942	Up-regulation
AGC_PKC_PKCa_PRKCB_ST	Q04637	EIF4G1	P05771-2	PRKCB	S895	G897E	897	Missense	proximal	2	no	0.592	2.288	EPSD	COSMIC	0.942	Gain
AGC_PKC_PKCa_PRKCB_ST	Q04637	EIF4G1	P05771-2	PRKCB	S895	G897R	897	Missense	proximal	2	no	0.592	9.326	EPSD	COSMIC;GDSC	0.942	Gain
AGC_PKC_PKCa_PRKCB_ST	Q04637	EIF4G1	P05771-2	PRKCB	S1028	G1034D	1034	Missense	distal	6	no	4.075	4.756	EPSD	COSMIC	0.942	Up-regulation
AGC_PKC_PKCa_PRKCB_ST	Q04637	EIF4G1	P05771-2	PRKCB	S1028	K1026R	1026	Missense	proximal	-2	no	4.075	3.965	EPSD	COSMIC	0.942	Down-regulation
AGC_PKC_PKCa_PRKCB_ST	Q04637	EIF4G1	P05771-2	PRKCB	S1028	P1035L	1035	Missense	distal	7	no	4.075	4.042	EPSD	COSMIC	0.942	Down-regulation
AGC_PKC_PKCa_PRKCB_ST	Q04637	EIF4G1	P05771-2	PRKCB	S1028	G1027D	1027	Missense	proximal	-1	no	4.075	4.202	EPSD	COSMIC	0.942	Up-regulation
AGC_PKC_PKCa_PRKCB_ST	Q04637	EIF4G1	P05771-2	PRKCB	S1028	R1031H	1031	Missense	distal	3	no	4.075	3.270	EPSD	COSMIC	0.942	Down-regulation
AGC_PKC_PKCa_PRKCB_ST	Q04637	EIF4G1	P05771-2	PRKCB	S1028	G1033S	1033	Missense	distal	5	no	4.075	4.098	EPSD	COSMIC	0.942	Up-regulation
AGC_PKC_PKCa_PRKCB_ST	Q04637	EIF4G1	P05771-2	PRKCB	S1028	G1034S	1034	Missense	distal	6	no	4.075	4.533	EPSD	COSMIC	0.942	Up-regulation
AGC_PKC_PKCa_PRKCB_ST	Q04637	EIF4G1	P05771-2	PRKCB	S1028	R1032H	1032	Missense	distal	4	no	4.075	3.253	EPSD	COSMIC	0.942	Down-regulation
AGC_PKC_PKCa_PRKCB_ST	Q04637	EIF4G1	P05771-2	PRKCB	S1077	T1073P	1073	Missense	distal	-4	no	2.648	2.794	EPSD	COSMIC	0.942	Up-regulation
AGC_PKC_PKCa_PRKCB_ST	Q04637	EIF4G1	P05771-2	PRKCB	S1077	L1084R	1084	Missense	distal	7	no	2.648	2.418	EPSD	COSMIC	0.942	Down-regulation
AGC_PKC_PKCa_PRKCB_ST	Q04637	EIF4G1	P05771-2	PRKCB	S1077	S1077F	1077	Missense	central	0	yes	2.648	0.000	EPSD	COSMIC	0.942	Loss
AGC_PKC_PKCa_PRKCB_ST	Q04637	EIF4G1	P05771-2	PRKCB	S1077	S1077P	1077	Missense	central	0	yes	2.648	0.000	EPSD	COSMIC	0.942	Loss
AGC_PKC_PKCa_PRKCB_ST	Q04637	EIF4G1	P05771-2	PRKCB	T1117	S1118R	1118	Missense	proximal	1	no	-0.671	1.353	EPSD	COSMIC	0.942	Gain
AGC_PKC_PKCa_PRKCB_ST	Q04637	EIF4G1	P05771-2	PRKCB	S1144	R1150M	1150	Missense	distal	6	no	1.474	0.539	EPSD	COSMIC	0.942	Loss
AGC_PKC_PKCa_PRKCB_ST	Q04637	EIF4G1	P05771-2	PRKCB	S1144	R1139H	1139	Missense	distal	-5	no	1.474	1.227	EPSD	COSMIC	0.942	Down-regulation
AGC_PKC_PKCa_PRKCB_ST	Q04637	EIF4G1	P05771-2	PRKCB	S1144	E1149Q	1149	Missense	distal	5	no	1.474	1.605	EPSD	COSMIC	0.942	Up-regulation
AGC_PKC_PKCa_PRKCB_ST	Q04637	EIF4G1	P05771-2	PRKCB	S1144	R1143M	1143	Missense	proximal	-1	no	1.474	1.063	EPSD	COSMIC	0.942	Down-regulation
AGC_PKC_PKCa_PRKCB_ST	Q04637	EIF4G1	P05771-2	PRKCB	S1144	G1151D	1151	Missense	distal	7	no	1.474	1.248	EPSD	COSMIC	0.942	Down-regulation
AGC_PKC_PKCa_PRKCB_ST	Q04637	EIF4G1	P05771-2	PRKCB	S1144	R1148Q	1148	Missense	distal	4	no	1.474	0.855	EPSD	COSMIC	0.942	Loss
AGC_PKC_PKCa_PRKCB_ST	Q04637	EIF4G1	P05771-2	PRKCB	S1164	E1162K	1162	Missense	proximal	-2	no	0.693	2.138	EPSD	COSMIC	0.942	Gain
AGC_PKC_PKCa_PRKCB_ST	Q04637	EIF4G1	P05771-2	PRKCB	S1164	R1160S	1160	Missense	distal	-4	no	0.693	1.017	EPSD	COSMIC	0.942	Gain
AGC_PKC_PKCa_PRKCB_ST	Q04637	EIF4G1	P05771-2	PRKCB	S1164	R1160P	1160	Missense	distal	-4	no	0.693	1.114	EPSD	COSMIC	0.942	Gain
AGC_PKC_PKCa_PRKCB_ST	Q04637	EIF4G1	P05771-2	PRKCB	S1164	R1157W	1157	Missense	distal	-7	no	0.693	1.115	EPSD	COSMIC	0.942	Gain
AGC_PKC_PKCa_PRKCB_ST	Q04637	EIF4G1	P05771-2	PRKCB	S1164	E1165Q	1165	Missense	proximal	1	no	0.693	1.873	EPSD	COSMIC	0.942	Gain
AGC_PKC_PKCa_PRKCB_ST	Q04637	EIF4G1	P05771-2	PRKCB	T1182	T1182I	1182	Missense	central	0	yes	2.924	0.000	EPSD	COSMIC	0.942	Loss
AGC_PKC_PKCa_PRKCB_ST	Q04637	EIF4G1	P05771-2	PRKCB	T1182	A1177G	1177	Missense	distal	-5	no	2.924	2.876	EPSD	COSMIC	0.942	Down-regulation
AGC_PKC_PKCa_PRKCB_ST	Q04637	EIF4G1	P05771-2	PRKCB	T1182	D1175Y	1175	Missense	distal	-7	no	2.924	2.996	EPSD	COSMIC	0.942	Up-regulation
AGC_PKC_PKCa_PRKCB_ST	Q04637	EIF4G1	P05771-2	PRKCB	T1182	A1177V	1177	Missense	distal	-5	no	2.924	2.895	EPSD	COSMIC	0.942	Down-regulation
AGC_PKC_PKCa_PRKCB_ST	Q04637	EIF4G1	P05771-2	PRKCB	T1182	R1176C	1176	Missense	distal	-6	no	2.924	2.569	EPSD	COSMIC	0.942	Down-regulation
AGC_PKC_PKCa_PRKCB_ST	Q04637	EIF4G1	P05771-2	PRKCB	T1182	R1178W	1178	Missense	distal	-4	no	2.924	3.502	EPSD	COSMIC	0.942	Up-regulation
AGC_PKC_PKCa_PRKCB_ST	Q04637	EIF4G1	P05771-2	PRKCB	T1182	S1187F	1187	Missense	distal	5	no	2.924	2.880	EPSD	COSMIC	0.942	Down-regulation
AGC_PKC_PKCa_PRKCB_ST	Q04637	EIF4G1	P05771-2	PRKCB	T1182	S1187P	1187	Missense	distal	5	no	2.924	2.867	EPSD	COSMIC	0.942	Down-regulation
AGC_PKC_PKCa_PRKCB_ST	Q04637	EIF4G1	P05771-2	PRKCB	S1185	T1182I	1182	Missense	distal	-3	no	1.016	0.302	EPSD	COSMIC	0.942	Loss
AGC_PKC_PKCa_PRKCB_ST	Q04637	EIF4G1	P05771-2	PRKCB	S1185	E1191D	1191	Missense	distal	6	no	1.016	0.616	EPSD	COSMIC	0.942	Loss
AGC_PKC_PKCa_PRKCB_ST	Q04637	EIF4G1	P05771-2	PRKCB	S1185	R1178W	1178	Missense	distal	-7	no	1.016	1.437	EPSD	COSMIC	0.942	Up-regulation
AGC_PKC_PKCa_PRKCB_ST	Q04637	EIF4G1	P05771-2	PRKCB	S1185	S1187F	1187	Missense	proximal	2	no	1.016	-0.676	EPSD	COSMIC	0.942	Loss
AGC_PKC_PKCa_PRKCB_ST	Q04637	EIF4G1	P05771-2	PRKCB	S1185	S1187P	1187	Missense	proximal	2	no	1.016	1.180	EPSD	COSMIC	0.942	Up-regulation
AGC_PKC_PKCa_PRKCB_ST	Q04637	EIF4G1	P05771-2	PRKCB	S1185	E1192D	1192	Missense	distal	7	no	1.016	0.957	EPSD	COSMIC	0.942	Down-regulation
AGC_PKC_PKCa_PRKCB_ST	Q04637	EIF4G1	P05771-2	PRKCB	S1209	R1214W	1214	Missense	distal	5	no	2.740	2.045	EPSD	COSMIC	0.942	Down-regulation
AGC_PKC_PKCa_PRKCB_ST	Q04637	EIF4G1	P05771-2	PRKCB	S1209	R1216C	1216	Missense	distal	7	no	2.740	2.937	EPSD	COSMIC	0.942	Up-regulation
AGC_PKC_PKCa_PRKCB_ST	Q04637	EIF4G1	P05771-2	PRKCB	S1209	T1211M	1211	Missense	proximal	2	no	2.740	0.622	EPSD	COSMIC;CCLE	0.942	Loss
AGC_PKC_PKCa_PRKCB_ST	Q04637	EIF4G1	P05771-2	PRKCB	S1209	R1205C	1205	Missense	distal	-4	no	2.740	3.246	EPSD	COSMIC	0.942	Up-regulation
AGC_PKC_PKCa_PRKCB_ST	Q04637	EIF4G1	P05771-2	PRKCB	S1209	E1212K	1212	Missense	distal	3	no	2.740	2.688	EPSD	COSMIC	0.942	Down-regulation
AGC_PKC_PKCa_PRKCB_ST	Q04637	EIF4G1	P05771-2	PRKCB	S1209	R1205H	1205	Missense	distal	-4	no	2.740	3.046	EPSD	COSMIC;GDSC	0.942	Up-regulation
AGC_PKC_PKCa_PRKCB_ST	Q04637	EIF4G1	P05771-2	PRKCB	S1209	E1202Q	1202	Missense	distal	-7	no	2.740	2.606	EPSD	COSMIC	0.942	Down-regulation
AGC_PKC_PKCa_PRKCB_ST	Q04637	EIF4G1	P05771-2	PRKCB	S1209	A1208G	1208	Missense	proximal	-1	no	2.740	2.783	EPSD	COSMIC	0.942	Up-regulation
AGC_PKC_PKCa_PRKCB_ST	Q04637	EIF4G1	P05771-2	PRKCB	S1209	E1212D	1212	Missense	distal	3	no	2.740	2.485	EPSD	COSMIC	0.942	Down-regulation
AGC_PKC_PKCa_PRKCB_ST	Q04637	EIF4G1	P05771-2	PRKCB	S1238	E1240K	1240	Missense	proximal	2	no	-4.155	1.259	EPSD	COSMIC	0.942	Gain
AGC_PKC_PKCa_PRKCB_ST	O15350	TP73	P05771-2	PRKCB	S326	S333R	333	Missense	distal	7	no	6.967	6.797	EPSD	COSMIC	0.942	Down-regulation
AGC_PKC_PKCa_PRKCB_ST	O15350	TP73	P05771-2	PRKCB	S388	R390W	390	Missense	proximal	2	no	2.009	-7.504	PhosphoSitePlus	COSMIC;CCLE	0.942	Loss
AGC_PKC_PKCa_PRKCB_ST	O15350	TP73	P05771-2	PRKCB	S388	R390H	390	Missense	proximal	2	no	2.009	-4.353	PhosphoSitePlus	COSMIC	0.942	Loss
AGC_PKC_PKCa_PRKCB_ST	O15350	TP73	P05771-2	PRKCB	S426	V427I	427	Missense	proximal	1	no	3.051	3.338	EPSD	COSMIC;CCLE	0.942	Up-regulation
AGC_PKC_PKCa_PRKCB_ST	P28329	CHAT	P05771-2	PRKCB	S244	L248V	248	Missense	distal	4	no	1.015	1.384	EPSD	COSMIC	0.942	Up-regulation
AGC_PKC_PKCa_PRKCB_ST	P28329	CHAT	P05771-2	PRKCB	S244	L248P	248	Missense	distal	4	no	1.015	1.438	EPSD	COSMIC	0.942	Up-regulation
AGC_PKC_PKCa_PRKCB_ST	P28329	CHAT	P05771-2	PRKCB	S244	S240F	240	Missense	distal	-4	no	1.015	0.994	EPSD	COSMIC	0.942	Down-regulation
AGC_PKC_PKCa_PRKCB_ST	P28329	CHAT	P05771-2	PRKCB	S244	L243F	243	Missense	proximal	-1	no	1.015	1.173	EPSD	COSMIC	0.942	Up-regulation
AGC_PKC_PKCa_PRKCB_ST	P28329	CHAT	P05771-2	PRKCB	S244	D250N	250	Missense	distal	6	no	1.015	1.282	EPSD	COSMIC	0.942	Up-regulation
AGC_PKC_PKCa_PRKCB_ST	P28329	CHAT	P05771-2	PRKCB	S244	S237N	237	Missense	distal	-7	no	1.015	1.002	EPSD	COSMIC	0.942	Down-regulation
AGC_PKC_PKCa_PRKCB_ST	P28329	CHAT	P05771-2	PRKCB	T373	R375Q	375	Missense	proximal	2	no	4.094	-2.455	EPSD	COSMIC	0.942	Loss
AGC_PKC_PKCa_PRKCB_ST	P28329	CHAT	P05771-2	PRKCB	T373	K370R	370	Missense	distal	-3	no	4.094	3.863	EPSD	COSMIC	0.942	Down-regulation
AGC_PKC_PKCa_PRKCB_ST	P28329	CHAT	P05771-2	PRKCB	T373	T366M	366	Missense	distal	-7	no	4.094	4.260	EPSD	COSMIC	0.942	Up-regulation
AGC_PKC_PKCa_PRKCB_ST	P28329	CHAT	P05771-2	PRKCB	T373	V369M	369	Missense	distal	-4	no	4.094	4.170	EPSD	COSMIC	0.942	Up-regulation
AGC_PKC_PKCa_PRKCB_ST	P28329	CHAT	P05771-2	PRKCB	T373	D376G	376	Missense	distal	3	no	4.094	3.725	EPSD	COSMIC	0.942	Down-regulation
AGC_PKC_PKCa_PRKCB_ST	P28329	CHAT	P05771-2	PRKCB	S377	R375Q	375	Missense	proximal	-2	no	1.429	0.457	EPSD	COSMIC	0.942	Loss
AGC_PKC_PKCa_PRKCB_ST	P28329	CHAT	P05771-2	PRKCB	S377	R383S	383	Missense	distal	6	no	1.429	0.460	EPSD	COSMIC	0.942	Loss
AGC_PKC_PKCa_PRKCB_ST	P28329	CHAT	P05771-2	PRKCB	S377	K370R	370	Missense	distal	-7	no	1.429	1.474	EPSD	COSMIC	0.942	Up-regulation
AGC_PKC_PKCa_PRKCB_ST	P28329	CHAT	P05771-2	PRKCB	S377	R383C	383	Missense	distal	6	no	1.429	0.235	EPSD	COSMIC	0.942	Loss
AGC_PKC_PKCa_PRKCB_ST	P28329	CHAT	P05771-2	PRKCB	S377	D376G	376	Missense	proximal	-1	no	1.429	1.303	EPSD	COSMIC	0.942	Down-regulation
AGC_PKC_PKCa_PRKCB_ST	P28329	CHAT	P05771-2	PRKCB	S377	R383H	383	Missense	distal	6	no	1.429	0.669	EPSD	COSMIC	0.942	Loss
AGC_PKC_PKCa_PRKCB_ST	P28329	CHAT	P05771-2	PRKCB	T462	R466Q	466	Missense	distal	4	no	1.163	0.543	EPSD	COSMIC	0.942	Loss
AGC_PKC_PKCa_PRKCB_ST	P28329	CHAT	P05771-2	PRKCB	T462	R466L	466	Missense	distal	4	no	1.163	-0.143	EPSD	COSMIC	0.942	Loss
AGC_PKC_PKCa_PRKCB_ST	P28329	CHAT	P05771-2	PRKCB	T462	E455D	455	Missense	distal	-7	no	1.163	1.085	EPSD	COSMIC	0.942	Down-regulation
AGC_PKC_PKCa_PRKCB_ST	P28329	CHAT	P05771-2	PRKCB	S464	R466Q	466	Missense	proximal	2	no	5.753	-0.796	EPSD	COSMIC	0.942	Loss
AGC_PKC_PKCa_PRKCB_ST	P28329	CHAT	P05771-2	PRKCB	S464	R466L	466	Missense	proximal	2	no	5.753	-0.879	EPSD	COSMIC	0.942	Loss
AGC_PKC_PKCa_PRKCB_ST	P28329	CHAT	P05771-2	PRKCB	S465	R466Q	466	Missense	proximal	1	no	4.475	3.777	EPSD	COSMIC	0.942	Down-regulation
AGC_PKC_PKCa_PRKCB_ST	P28329	CHAT	P05771-2	PRKCB	S465	R466L	466	Missense	proximal	1	no	4.475	3.791	EPSD	COSMIC	0.942	Down-regulation
AGC_PKC_PKCa_PRKCB_ST	P28329	CHAT	P05771-2	PRKCB	S558	E555K	555	Missense	distal	-3	no	6.129	9.464	EPSD	COSMIC	0.942	Up-regulation
AGC_PKC_PKCa_PRKCB_ST	P28329	CHAT	P05771-2	PRKCB	S558	A557T	557	Missense	proximal	-1	no	6.129	6.283	EPSD	COSMIC;GDSC	0.942	Up-regulation
AGC_PKC_PKCa_PRKCB_ST	P28329	CHAT	P05771-2	PRKCB	S558	R560C	560	Missense	proximal	2	no	6.129	1.635	EPSD	COSMIC	0.942	Down-regulation
AGC_PKC_PKCa_PRKCB_ST	P28329	CHAT	P05771-2	PRKCB	S558	V551A	551	Missense	distal	-7	no	6.129	6.092	EPSD	COSMIC	0.942	Down-regulation
AGC_PKC_PKCa_PRKCB_ST	P28329	CHAT	P05771-2	PRKCB	S594	K588M	588	Missense	distal	-6	no	2.132	1.818	EPSD	COSMIC	0.942	Down-regulation
AGC_PKC_PKCa_PRKCB_ST	P28329	CHAT	P05771-2	PRKCB	S594	L599F	599	Missense	distal	5	no	2.132	2.138	EPSD	COSMIC	0.942	Up-regulation
AGC_PKC_PKCa_PRKCB_ST	P28329	CHAT	P05771-2	PRKCB	S594	E595K	595	Missense	proximal	1	no	2.132	4.124	EPSD	COSMIC	0.942	Up-regulation
AGC_PKC_PKCa_PRKCB_ST	P35637	FUS	P05771-2	PRKCB	S257	G255R	255	Missense	proximal	-2	no	4.568	6.435	PhosphoSitePlus	COSMIC	0.942	Up-regulation
AGC_PKC_PKCa_PRKCB_ST	P35637	FUS	P05771-2	PRKCB	S257	R259L	259	Missense	proximal	2	no	4.568	-2.064	PhosphoSitePlus	COSMIC	0.942	Loss
AGC_PKC_PKCa_PRKCB_ST	P35637	FUS	P05771-2	PRKCB	S257	G255C	255	Missense	proximal	-2	no	4.568	4.969	PhosphoSitePlus	COSMIC	0.942	Up-regulation
AGC_PKC_PKCa_PRKCB_ST	P35637	FUS	P05771-2	PRKCB	S277	D270V	270	Missense	distal	-7	no	1.565	1.761	EPSD	COSMIC	0.942	Up-regulation
AGC_PKC_PKCa_PRKCB_ST	P35637	FUS	P05771-2	PRKCB	S277	R274C	274	Missense	distal	-3	no	1.565	-2.334	EPSD	COSMIC	0.942	Loss
AGC_PKC_PKCa_PRKCB_ST	P35637	FUS	P05771-2	PRKCB	S277	D280E	280	Missense	distal	3	no	1.565	1.820	EPSD	COSMIC	0.942	Up-regulation
AGC_PKC_PKCa_PRKCB_ST	P35637	FUS	P05771-2	PRKCB	T326	P320S	320	Missense	distal	-6	no	2.138	2.252	EPSD	COSMIC	0.942	Up-regulation
AGC_PKC_PKCa_PRKCB_ST	P35637	FUS	P05771-2	PRKCB	T326	I322F	322	Missense	distal	-4	no	2.138	2.145	EPSD	COSMIC	0.942	Up-regulation
AGC_PKC_PKCa_PRKCB_ST	P35637	FUS	P05771-2	PRKCB	S346	S340F	340	Missense	distal	-6	no	1.509	1.404	EPSD	COSMIC	0.942	Down-regulation
AGC_PKC_PKCa_PRKCB_ST	P35637	FUS	P05771-2	PRKCB	S360	P363H	363	Missense	distal	3	no	1.325	1.219	EPSD	COSMIC	0.942	Down-regulation
AGC_PKC_PKCa_PRKCB_ST	P35637	FUS	P05771-2	PRKCB	S360	P363S	363	Missense	distal	3	no	1.325	1.259	EPSD	COSMIC	0.942	Down-regulation
AGC_PKC_PKCa_PRKCB_ST	P35637	FUS	P05771-2	PRKCB	S439	F438V	438	Missense	proximal	-1	no	4.862	4.844	EPSD	COSMIC	0.942	Down-regulation
AGC_PKC_PKCa_PRKCB_ST	P35637	FUS	P05771-2	PRKCB	S439	R441S	441	Missense	proximal	2	no	4.862	-1.135	EPSD	COSMIC	0.942	Loss
AGC_PKC_PKCa_PRKCB_ST	P35637	FUS	P05771-2	PRKCB	S439	S439C	439	Missense	central	0	yes	4.862	0.000	EPSD	COSMIC	0.942	Loss
AGC_PKC_PKCa_PRKCB_ST	Q9UBU3	GHRL	P05771-2	PRKCB	S41	P44L	44	Missense	distal	3	no	9.523	9.136	PhosphoSitePlus	COSMIC	0.942	Down-regulation
AGC_PKC_PKCa_PRKCB_ST	Q9UBU3	GHRL	P05771-2	PRKCB	S41	E40K	40	Missense	proximal	-1	no	9.523	9.667	PhosphoSitePlus	COSMIC	0.942	Up-regulation
AGC_PKC_PKCa_PRKCB_ST	Q9UBU3	GHRL	P05771-2	PRKCB	S41	P45L	45	Missense	distal	4	no	9.523	9.101	PhosphoSitePlus	COSMIC	0.942	Down-regulation
AGC_PKC_PKCa_PRKCB_ST	Q9UBU3	GHRL	P05771-2	PRKCB	S41	R38Q	38	Missense	distal	-3	no	9.523	6.325	PhosphoSitePlus	COSMIC	0.942	Down-regulation
AGC_PKC_PKCa_PRKCB_ST	P49840	GSK3A	P05771-2	PRKCB	S266	Q269R	269	Missense	distal	3	no	2.948	3.512	EPSD	COSMIC	0.942	Up-regulation
AGC_PKC_PKCa_PRKCB_ST	P49840	GSK3A	P05771-2	PRKCB	S266	G265V	265	Missense	proximal	-1	no	2.948	3.010	EPSD	COSMIC	0.942	Up-regulation
TK_Syk_SYK_Y	P02730	SLC4A1	P43405	SYK	Y8	M11T	11	Missense	distal	3	no	18.384	15.918	EPSD;PhosphoSitePlus	COSMIC	13.041	Down-regulation
TK_Syk_SYK_Y	P02730	SLC4A1	P43405	SYK	Y8	D6Y	6	Missense	proximal	-2	no	18.384	14.194	EPSD;PhosphoSitePlus	COSMIC	13.041	Down-regulation
TK_Syk_SYK_Y	P02730	SLC4A1	P43405	SYK	Y21	E17Q	17	Missense	distal	-4	no	26.467	24.770	EPSD;PhosphoSitePlus	COSMIC	13.041	Down-regulation
TK_Syk_SYK_Y	P02730	SLC4A1	P43405	SYK	Y21	Y21C	21	Missense	central	0	yes	26.467	0.000	EPSD;PhosphoSitePlus	COSMIC	13.041	Loss
TK_Syk_SYK_Y	P02730	SLC4A1	P43405	SYK	Y359	N365S	365	Missense	distal	6	no	17.193	17.206	EPSD;PhosphoSitePlus	COSMIC	13.041	Up-regulation
TK_Syk_SYK_Y	P02730	SLC4A1	P43405	SYK	Y359	D355N	355	Missense	distal	-4	no	17.193	15.950	EPSD;PhosphoSitePlus	COSMIC	13.041	Down-regulation
TK_Syk_SYK_Y	P02730	SLC4A1	P43405	SYK	Y904	D902N	902	Missense	proximal	-2	no	22.145	20.125	PhosphoSitePlus;EPSD	COSMIC	13.041	Down-regulation
TK_Syk_SYK_Y	P02730	SLC4A1	P43405	SYK	Y904	V907L	907	Missense	distal	3	no	22.145	21.104	PhosphoSitePlus;EPSD	COSMIC	13.041	Down-regulation
TK_Syk_SYK_Y	P29353	SHC1	P43405	SYK	Y349	E343K	343	Missense	distal	-6	no	15.004	14.173	EPSD	COSMIC	13.041	Down-regulation
TK_Syk_SYK_Y	P29353	SHC1	P43405	SYK	Y349	N351Y	351	Missense	proximal	2	no	15.004	12.807	EPSD	COSMIC	13.041	Loss
TK_Syk_SYK_Y	P29353	SHC1	P43405	SYK	Y349	P354L	354	Missense	distal	5	no	15.004	15.108	EPSD	COSMIC	13.041	Up-regulation
TK_Syk_SYK_Y	P29353	SHC1	P43405	SYK	Y349	E343D	343	Missense	distal	-6	no	15.004	14.624	EPSD	COSMIC	13.041	Down-regulation
TK_Syk_SYK_Y	P29353	SHC1	P43405	SYK	Y350	E343K	343	Missense	distal	-7	no	15.904	15.138	EPSD	COSMIC	13.041	Down-regulation
TK_Syk_SYK_Y	P29353	SHC1	P43405	SYK	Y350	E357D	357	Missense	distal	7	no	15.904	16.093	EPSD	COSMIC;GDSC	13.041	Up-regulation
TK_Syk_SYK_Y	P29353	SHC1	P43405	SYK	Y350	N351Y	351	Missense	proximal	1	no	15.904	15.140	EPSD	COSMIC	13.041	Down-regulation
TK_Syk_SYK_Y	P29353	SHC1	P43405	SYK	Y350	P354L	354	Missense	distal	4	no	15.904	14.927	EPSD	COSMIC	13.041	Down-regulation
TK_Syk_SYK_Y	P29353	SHC1	P43405	SYK	Y350	E343D	343	Missense	distal	-7	no	15.904	15.481	EPSD	COSMIC	13.041	Down-regulation
TK_Syk_SYK_Y	P29353	SHC1	P43405	SYK	Y427	V430I	430	Missense	distal	3	no	19.290	17.526	EPSD	COSMIC	13.041	Down-regulation
TK_Syk_SYK_Y	P29353	SHC1	P43405	SYK	Y427	S426C	426	Missense	proximal	-1	no	19.290	15.834	EPSD	COSMIC	13.041	Down-regulation
TK_Syk_SYK_Y	P29353	SHC1	P43405	SYK	Y427	S426P	426	Missense	proximal	-1	no	19.290	17.540	EPSD	COSMIC	13.041	Down-regulation
TK_Syk_SYK_Y	P31995	FCGR2C	P43405	SYK	Y287	G292S	292	Missense	distal	5	no	23.271	23.248	EPSD;PhosphoSitePlus	COSMIC	13.041	Down-regulation
TK_Syk_SYK_Y	P31995	FCGR2C	P43405	SYK	Y294	G292S	292	Missense	proximal	-2	no	16.044	16.698	EPSD	COSMIC	13.041	Up-regulation
TK_Syk_SYK_Y	P31995	FCGR2C	P43405	SYK	Y310	D304N	304	Missense	distal	-6	no	15.234	14.785	PhosphoSitePlus;EPSD	COSMIC	13.041	Down-regulation
TK_Syk_SYK_Y	P31995	FCGR2C	P43405	SYK	Y310	P314L	314	Missense	distal	4	no	15.234	14.257	PhosphoSitePlus;EPSD	COSMIC	13.041	Down-regulation
TK_Syk_SYK_Y	Q8IWV1	LAX1	P43405	SYK	Y193	P197L	197	Missense	distal	4	no	21.486	20.509	EPSD;PhosphoSitePlus	COSMIC	13.041	Down-regulation
TK_Syk_SYK_Y	Q8IWV1	LAX1	P43405	SYK	Y193	H191N	191	Missense	proximal	-2	no	21.486	22.643	EPSD;PhosphoSitePlus	COSMIC	13.041	Up-regulation
TK_Syk_SYK_Y	Q8IWV1	LAX1	P43405	SYK	Y373	E368K	368	Missense	distal	-5	no	29.132	28.478	EPSD;PhosphoSitePlus	COSMIC	13.041	Down-regulation
TK_Syk_SYK_Y	Q8IWV1	LAX1	P43405	SYK	Y373	D372N	372	Missense	proximal	-1	no	29.132	27.642	EPSD;PhosphoSitePlus	COSMIC;GDSC;CCLE	13.041	Down-regulation
TK_Syk_SYK_Y	Q8IWV1	LAX1	P43405	SYK	Y373	S370F	370	Missense	distal	-3	no	29.132	24.608	EPSD;PhosphoSitePlus	COSMIC	13.041	Down-regulation
TK_Syk_SYK_Y	P19174	PLCG1	P43405	SYK	Y472	E473K	473	Missense	proximal	1	no	16.799	13.318	EPSD	COSMIC	13.041	Down-regulation
TK_Syk_SYK_Y	P19174	PLCG1	P43405	SYK	Y771	Y775F	775	Missense	distal	4	no	17.856	17.410	PhosphoSitePlus;EPSD	COSMIC	13.041	Down-regulation
TK_Syk_SYK_Y	P19174	PLCG1	P43405	SYK	Y1253	Q1254K	1254	Missense	proximal	1	no	10.861	13.152	EPSD	COSMIC	13.041	Gain
TK_Syk_SYK_Y	Q8WV28	BLNK	P43405	SYK	Y72	Y72C	72	Missense	central	0	yes	26.174	0.000	EPSD;PhosphoSitePlus	COSMIC	13.041	Loss
TK_Syk_SYK_Y	Q8WV28	BLNK	P43405	SYK	Y72	D71N	71	Missense	proximal	-1	no	26.174	24.684	EPSD;PhosphoSitePlus	COSMIC	13.041	Down-regulation
TK_Syk_SYK_Y	Q8WV28	BLNK	P43405	SYK	Y84	S81L	81	Missense	distal	-3	no	22.896	17.776	EPSD;PhosphoSitePlus	COSMIC;CCLE	13.041	Down-regulation
TK_Syk_SYK_Y	Q8WV28	BLNK	P43405	SYK	Y84	E89K	89	Missense	distal	5	no	22.896	23.083	EPSD;PhosphoSitePlus	COSMIC	13.041	Up-regulation
TK_Syk_SYK_Y	Q8WV28	BLNK	P43405	SYK	Y84	M86T	86	Missense	proximal	2	no	22.896	23.631	EPSD;PhosphoSitePlus	COSMIC;CCLE	13.041	Up-regulation
TK_Syk_SYK_Y	Q8WV28	BLNK	P43405	SYK	Y96	P100S	100	Missense	distal	4	no	27.373	27.315	PhosphoSitePlus;EPSD	COSMIC	13.041	Down-regulation
TK_Syk_SYK_Y	Q8WV28	BLNK	P43405	SYK	Y96	E89K	89	Missense	distal	-7	no	27.373	26.606	PhosphoSitePlus;EPSD	COSMIC	13.041	Down-regulation
TK_Syk_SYK_Y	Q8WV28	BLNK	P43405	SYK	Y96	D94E	94	Missense	proximal	-2	no	27.373	26.566	PhosphoSitePlus;EPSD	COSMIC	13.041	Down-regulation
TK_Syk_SYK_Y	Q8WV28	BLNK	P43405	SYK	Y178	V180I	180	Missense	proximal	2	no	20.252	20.627	EPSD;PhosphoSitePlus	COSMIC	13.041	Up-regulation
TK_Syk_SYK_Y	Q8WV28	BLNK	P43405	SYK	Y178	L172F	172	Missense	distal	-6	no	20.252	19.782	EPSD;PhosphoSitePlus	COSMIC	13.041	Down-regulation
TK_Syk_SYK_Y	Q8WV28	BLNK	P43405	SYK	Y178	N185H	185	Missense	distal	7	no	20.252	20.057	EPSD;PhosphoSitePlus	COSMIC	13.041	Down-regulation
TK_Syk_SYK_Y	Q8WV28	BLNK	P43405	SYK	Y178	E175K	175	Missense	distal	-3	no	20.252	17.372	EPSD;PhosphoSitePlus	COSMIC	13.041	Down-regulation
TK_Syk_SYK_Y	Q8WV28	BLNK	P43405	SYK	Y189	N185H	185	Missense	distal	-4	no	24.592	23.520	EPSD;PhosphoSitePlus	COSMIC	13.041	Down-regulation
TK_Syk_SYK_Y	Q8WV28	BLNK	P43405	SYK	Y189	P192T	192	Missense	distal	3	no	24.592	20.475	EPSD;PhosphoSitePlus	COSMIC;GDSC;CCLE	13.041	Down-regulation
TK_Syk_SYK_Y	Q8WV28	BLNK	P43405	SYK	Y189	P192L	192	Missense	distal	3	no	24.592	20.857	EPSD;PhosphoSitePlus	COSMIC	13.041	Down-regulation
TK_Syk_SYK_Y	P16885	PLCG2	P43405	SYK	Y680	T683A	683	Missense	distal	3	no	12.648	14.850	EPSD	COSMIC	13.041	Gain
TK_Syk_SYK_Y	P16885	PLCG2	P43405	SYK	Y759	P762L	762	Missense	distal	3	no	16.328	12.594	PhosphoSitePlus	COSMIC	13.041	Loss
TK_Syk_SYK_Y	P16885	PLCG2	P43405	SYK	Y759	M758I	758	Missense	proximal	-1	no	16.328	16.346	PhosphoSitePlus	COSMIC	13.041	Up-regulation
TK_Syk_SYK_Y	P16885	PLCG2	P43405	SYK	Y811	G809A	809	Missense	proximal	-2	no	13.402	11.634	EPSD	COSMIC	13.041	Loss
TK_Syk_SYK_Y	P16885	PLCG2	P43405	SYK	Y811	W806L	806	Missense	distal	-5	no	13.402	13.576	EPSD	COSMIC	13.041	Up-regulation
TK_Syk_SYK_Y	P16885	PLCG2	P43405	SYK	Y811	G804W	804	Missense	distal	-7	no	13.402	12.580	EPSD	COSMIC	13.041	Loss
TK_Syk_SYK_Y	P16885	PLCG2	P43405	SYK	Y811	G809R	809	Missense	proximal	-2	no	13.402	12.145	EPSD	COSMIC	13.041	Loss
TK_Syk_SYK_Y	P16885	PLCG2	P43405	SYK	Y1048	E1041Q	1041	Missense	distal	-7	no	16.841	15.754	EPSD	COSMIC	13.041	Down-regulation
TK_Syk_SYK_Y	P16885	PLCG2	P43405	SYK	Y1048	E1041K	1041	Missense	distal	-7	no	16.841	16.074	EPSD	COSMIC	13.041	Down-regulation
TK_Syk_SYK_Y	P16885	PLCG2	P43405	SYK	Y1048	E1054Q	1054	Missense	distal	6	no	16.841	16.336	EPSD	COSMIC	13.041	Down-regulation
TK_Syk_SYK_Y	P14317	HCLS1	P43405	SYK	Y83	G85D	85	Missense	proximal	2	no	10.664	13.506	EPSD	COSMIC	13.041	Gain
TK_Syk_SYK_Y	P14317	HCLS1	P43405	SYK	Y83	G84E	84	Missense	proximal	1	no	10.664	13.916	EPSD	COSMIC	13.041	Gain
TK_Syk_SYK_Y	P14317	HCLS1	P43405	SYK	Y177	L173Q	173	Missense	distal	-4	no	12.126	13.523	EPSD	COSMIC	13.041	Gain
TK_Syk_SYK_Y	P14317	HCLS1	P43405	SYK	Y177	G174E	174	Missense	distal	-3	no	12.126	14.783	EPSD	COSMIC	13.041	Gain
TK_Syk_SYK_Y	P14317	HCLS1	P43405	SYK	Y177	A171E	171	Missense	distal	-6	no	12.126	13.552	EPSD	COSMIC	13.041	Gain
TK_Syk_SYK_Y	P14317	HCLS1	P43405	SYK	Y378	E373A	373	Missense	distal	-5	no	30.061	29.107	PhosphoSitePlus;EPSD	COSMIC;CCLE	13.041	Down-regulation
TK_Syk_SYK_Y	P14317	HCLS1	P43405	SYK	Y378	M384I	384	Missense	distal	6	no	30.061	30.032	PhosphoSitePlus;EPSD	COSMIC	13.041	Down-regulation
TK_Syk_SYK_Y	P14317	HCLS1	P43405	SYK	Y378	E382A	382	Missense	distal	4	no	30.061	29.749	PhosphoSitePlus;EPSD	COSMIC	13.041	Down-regulation
TK_Syk_SYK_Y	P14317	HCLS1	P43405	SYK	Y397	D396E	396	Missense	proximal	-1	no	29.543	27.872	EPSD;PhosphoSitePlus	COSMIC	13.041	Down-regulation
TK_Syk_SYK_Y	P14317	HCLS1	P43405	SYK	Y397	E392K	392	Missense	distal	-5	no	29.543	28.888	EPSD;PhosphoSitePlus	COSMIC	13.041	Down-regulation
TK_Syk_SYK_Y	P14317	HCLS1	P43405	SYK	Y397	E404Q	404	Missense	distal	7	no	29.543	29.087	EPSD;PhosphoSitePlus	COSMIC;CCLE	13.041	Down-regulation
TK_Syk_SYK_Y	P14317	HCLS1	P43405	SYK	Y397	G395E	395	Missense	proximal	-2	no	29.543	31.323	EPSD;PhosphoSitePlus	COSMIC	13.041	Up-regulation
TK_Syk_SYK_Y	P12318	FCGR2A	P43405	SYK	Y281	T277I	277	Missense	distal	-4	no	23.005	21.806	EPSD;PhosphoSitePlus	COSMIC	13.041	Down-regulation
TK_Syk_SYK_Y	P12318	FCGR2A	P43405	SYK	Y281	G286D	286	Missense	distal	5	no	23.005	22.902	EPSD;PhosphoSitePlus	COSMIC	13.041	Down-regulation
TK_Syk_SYK_Y	P12318	FCGR2A	P43405	SYK	Y281	G286S	286	Missense	distal	5	no	23.005	22.982	EPSD;PhosphoSitePlus	COSMIC;CCLE	13.041	Down-regulation
TK_Syk_SYK_Y	P12318	FCGR2A	P43405	SYK	Y288	G286D	286	Missense	proximal	-2	no	15.595	18.181	EPSD	COSMIC	13.041	Up-regulation
TK_Syk_SYK_Y	P12318	FCGR2A	P43405	SYK	Y288	G286S	286	Missense	proximal	-2	no	15.595	16.249	EPSD	COSMIC;CCLE	13.041	Up-regulation
TK_Syk_SYK_Y	P12318	FCGR2A	P43405	SYK	Y304	P309S	309	Missense	distal	5	no	15.344	15.251	PhosphoSitePlus;EPSD	COSMIC	13.041	Down-regulation
TK_Syk_SYK_Y	Q13422	IKZF1	P43405	SYK	Y293	L288M	288	Missense	distal	-5	no	15.490	16.108	EPSD	COSMIC	13.041	Up-regulation
TK_Syk_SYK_Y	Q13422	IKZF1	P43405	SYK	Y293	A297T	297	Missense	distal	4	no	15.490	15.656	EPSD	COSMIC	13.041	Up-regulation
TK_Syk_SYK_Y	Q13422	IKZF1	P43405	SYK	Y293	D290N	290	Missense	distal	-3	no	15.490	13.010	EPSD	COSMIC	13.041	Loss
TK_Syk_SYK_Y	Q13422	IKZF1	P43405	SYK	Y293	E300K	300	Missense	distal	7	no	15.490	15.172	EPSD	COSMIC	13.041	Down-regulation
TK_Syk_SYK_Y	Q13422	IKZF1	P43405	SYK	Y293	S298T	298	Missense	distal	5	no	15.490	15.611	EPSD	COSMIC	13.041	Up-regulation
TK_Syk_SYK_Y	Q13422	IKZF1	P43405	SYK	Y293	P292S	292	Missense	proximal	-1	no	15.490	17.240	EPSD	COSMIC	13.041	Up-regulation
TK_Syk_SYK_Y	Q13422	IKZF1	P43405	SYK	Y293	S289Y	289	Missense	distal	-4	no	15.490	14.028	EPSD	COSMIC	13.041	Down-regulation
TK_Syk_SYK_Y	Q13422	IKZF1	P43405	SYK	Y293	D290E	290	Missense	distal	-3	no	15.490	14.799	EPSD	COSMIC	13.041	Down-regulation
TK_Syk_SYK_Y	Q13422	IKZF1	P43405	SYK	Y293	S295G	295	Missense	proximal	2	no	15.490	15.119	EPSD	COSMIC	13.041	Down-regulation
TK_Syk_SYK_Y	Q13422	IKZF1	P43405	SYK	Y293	D290Y	290	Missense	distal	-3	no	15.490	10.059	EPSD	COSMIC	13.041	Loss
TK_Syk_SYK_Y	Q13422	IKZF1	P43405	SYK	Y293	T291R	291	Missense	proximal	-2	no	15.490	14.489	EPSD	COSMIC	13.041	Down-regulation
TK_Syk_SYK_Y	Q13422	IKZF1	P43405	SYK	Y293	E300Q	300	Missense	distal	7	no	15.490	15.035	EPSD	COSMIC	13.041	Down-regulation
TK_Syk_SYK_Y	Q13422	IKZF1	P43405	SYK	Y293	E300D	300	Missense	distal	7	no	15.490	15.679	EPSD	COSMIC	13.041	Up-regulation
TK_Syk_SYK_Y	Q13422	IKZF1	P43405	SYK	Y293	S296C	296	Missense	distal	3	no	15.490	13.422	EPSD	COSMIC	13.041	Down-regulation
TK_Syk_SYK_Y	Q13422	IKZF1	P43405	SYK	Y293	E300V	300	Missense	distal	7	no	15.490	14.879	EPSD	COSMIC	13.041	Down-regulation
TK_Syk_SYK_Y	Q13422	IKZF1	P43405	SYK	Y293	G287E	287	Missense	distal	-6	no	15.490	16.385	EPSD	COSMIC	13.041	Up-regulation
TK_Syk_SYK_Y	Q13422	IKZF1	P43405	SYK	Y299	E302K	302	Missense	distal	3	no	18.251	16.573	EPSD	COSMIC	13.041	Down-regulation
TK_Syk_SYK_Y	Q13422	IKZF1	P43405	SYK	Y299	E302G	302	Missense	distal	3	no	18.251	17.363	EPSD	COSMIC	13.041	Down-regulation
TK_Syk_SYK_Y	Q13422	IKZF1	P43405	SYK	Y299	M305I	305	Missense	distal	6	no	18.251	18.223	EPSD	COSMIC	13.041	Down-regulation
TK_Syk_SYK_Y	Q13422	IKZF1	P43405	SYK	Y299	E304K	304	Missense	distal	5	no	18.251	18.439	EPSD	COSMIC	13.041	Up-regulation
TK_Syk_SYK_Y	Q13422	IKZF1	P43405	SYK	Y299	A297T	297	Missense	proximal	-2	no	18.251	19.763	EPSD	COSMIC	13.041	Up-regulation
TK_Syk_SYK_Y	Q13422	IKZF1	P43405	SYK	Y299	E304Q	304	Missense	distal	5	no	18.251	18.526	EPSD	COSMIC	13.041	Up-regulation
TK_Syk_SYK_Y	Q13422	IKZF1	P43405	SYK	Y299	E300K	300	Missense	proximal	1	no	18.251	14.770	EPSD	COSMIC	13.041	Down-regulation
TK_Syk_SYK_Y	Q13422	IKZF1	P43405	SYK	Y299	M305L	305	Missense	distal	6	no	18.251	17.883	EPSD	COSMIC	13.041	Down-regulation
TK_Syk_SYK_Y	Q13422	IKZF1	P43405	SYK	Y299	M306I	306	Missense	distal	7	no	18.251	18.136	EPSD	COSMIC	13.041	Down-regulation
TK_Syk_SYK_Y	Q13422	IKZF1	P43405	SYK	Y299	S298T	298	Missense	proximal	-1	no	18.251	17.796	EPSD	COSMIC	13.041	Down-regulation
TK_Syk_SYK_Y	Q13422	IKZF1	P43405	SYK	Y299	P292S	292	Missense	distal	-7	no	18.251	18.519	EPSD	COSMIC	13.041	Up-regulation
TK_Syk_SYK_Y	Q13422	IKZF1	P43405	SYK	Y299	S295G	295	Missense	distal	-4	no	18.251	17.490	EPSD	COSMIC	13.041	Down-regulation
TK_Syk_SYK_Y	Q13422	IKZF1	P43405	SYK	Y299	E300Q	300	Missense	proximal	1	no	18.251	12.479	EPSD	COSMIC	13.041	Loss
TK_Syk_SYK_Y	Q13422	IKZF1	P43405	SYK	Y299	E300D	300	Missense	proximal	1	no	18.251	14.611	EPSD	COSMIC	13.041	Down-regulation
TK_Syk_SYK_Y	Q13422	IKZF1	P43405	SYK	Y299	S296C	296	Missense	distal	-3	no	18.251	13.975	EPSD	COSMIC	13.041	Down-regulation
TK_Syk_SYK_Y	Q13422	IKZF1	P43405	SYK	Y299	E300V	300	Missense	proximal	1	no	18.251	14.530	EPSD	COSMIC	13.041	Down-regulation
TK_Syk_SYK_Y	Q13422	IKZF1	P43405	SYK	Y321	A318T	318	Missense	distal	-3	no	10.848	13.115	EPSD	COSMIC	13.041	Gain
TK_Syk_SYK_Y	P13569	CFTR	P43405	SYK	Y512	D513N	513	Missense	proximal	1	no	13.984	12.666	PhosphoSitePlus	COSMIC	13.041	Loss
TK_Syk_SYK_Y	P13569	CFTR	P43405	SYK	Y512	Y512C	512	Missense	central	0	yes	13.984	0.000	PhosphoSitePlus	COSMIC	13.041	Loss
TK_Syk_SYK_Y	P13569	CFTR	P43405	SYK	Y512	R516K	516	Missense	distal	4	no	13.984	14.040	PhosphoSitePlus	COSMIC	13.041	Up-regulation
TK_Syk_SYK_Y	P13569	CFTR	P43405	SYK	Y512	D513H	513	Missense	proximal	1	no	13.984	11.842	PhosphoSitePlus	COSMIC	13.041	Loss
TK_Syk_SYK_Y	Q9GZY6	LAT2	P43405	SYK	Y40	R46C	46	Missense	distal	6	no	13.112	12.892	EPSD	COSMIC	13.041	Loss
TK_Syk_SYK_Y	Q9GZY6	LAT2	P43405	SYK	Y40	I39M	39	Missense	proximal	-1	no	13.112	13.094	EPSD	COSMIC	13.041	Down-regulation
TK_Syk_SYK_Y	Q9GZY6	LAT2	P43405	SYK	Y110	E108K	108	Missense	proximal	-2	no	20.418	18.531	EPSD	COSMIC	13.041	Down-regulation
TK_Syk_SYK_Y	Q9GZY6	LAT2	P43405	SYK	Y110	G105E	105	Missense	distal	-5	no	20.418	21.004	EPSD	COSMIC	13.041	Up-regulation
TK_Syk_SYK_Y	Q9GZY6	LAT2	P43405	SYK	Y136	E137V	137	Missense	proximal	1	no	21.870	18.149	EPSD;PhosphoSitePlus	COSMIC	13.041	Down-regulation
TK_Syk_SYK_Y	Q9GZY6	LAT2	P43405	SYK	Y193	E186G	186	Missense	distal	-7	no	22.652	21.855	EPSD;PhosphoSitePlus	COSMIC;GDSC;CCLE	13.041	Down-regulation
TK_Syk_SYK_Y	Q9GZY6	LAT2	P43405	SYK	Y193	E186K	186	Missense	distal	-7	no	22.652	21.886	EPSD;PhosphoSitePlus	COSMIC	13.041	Down-regulation
TK_Syk_SYK_Y	Q9GZY6	LAT2	P43405	SYK	Y193	S198F	198	Missense	distal	5	no	22.652	23.038	EPSD;PhosphoSitePlus	COSMIC	13.041	Up-regulation
TK_Syk_SYK_Y	Q9GZY6	LAT2	P43405	SYK	Y233	E227K	227	Missense	distal	-6	no	21.413	20.582	PhosphoSitePlus;EPSD	COSMIC	13.041	Down-regulation
TK_Syk_SYK_Y	Q9GZY6	LAT2	P43405	SYK	Y233	A239P	239	Missense	distal	6	no	21.413	21.599	PhosphoSitePlus;EPSD	COSMIC	13.041	Up-regulation
TK_Syk_SYK_Y	Q14247	CTTN	P43405	SYK	Y228	S224F	224	Missense	distal	-4	no	13.148	10.836	EPSD	COSMIC	13.041	Loss
TK_Syk_SYK_Y	Q14247	CTTN	P43405	SYK	Y310	G311E	311	Missense	proximal	1	no	10.988	14.240	EPSD	COSMIC	13.041	Gain
TK_Syk_SYK_Y	Q14247	CTTN	P43405	SYK	Y421	V420I	420	Missense	proximal	-1	no	19.566	20.613	PhosphoSitePlus	COSMIC	13.041	Up-regulation
TK_Syk_SYK_Y	Q14247	CTTN	P43405	SYK	Y421	S426F	426	Missense	distal	5	no	19.566	19.952	PhosphoSitePlus	COSMIC	13.041	Up-regulation
TK_Syk_SYK_Y	Q14247	CTTN	P43405	SYK	Y433	S438N	438	Missense	distal	5	no	13.165	13.225	EPSD	COSMIC	13.041	Up-regulation
TK_Syk_SYK_Y	Q14247	CTTN	P43405	SYK	Y433	T440P	440	Missense	distal	7	no	13.165	13.177	EPSD	COSMIC	13.041	Up-regulation
TK_Syk_SYK_Y	Q14247	CTTN	P43405	SYK	Y433	V437L	437	Missense	distal	4	no	13.165	12.704	EPSD	COSMIC	13.041	Loss
TK_Syk_SYK_Y	Q14247	CTTN	P43405	SYK	Y433	S426F	426	Missense	distal	-7	no	13.165	12.053	EPSD	COSMIC	13.041	Loss
TK_Syk_SYK_Y	Q14247	CTTN	P43405	SYK	Y470	Y464C	464	Missense	distal	-6	no	16.470	16.271	EPSD	COSMIC	13.041	Down-regulation
TK_Syk_SYK_Y	Q14247	CTTN	P43405	SYK	Y470	A463T	463	Missense	distal	-7	no	16.470	16.837	EPSD	COSMIC	13.041	Up-regulation
TK_Syk_SYK_Y	Q14247	CTTN	P43405	SYK	Y470	P476L	476	Missense	distal	6	no	16.470	16.064	EPSD	COSMIC;GDSC;CCLE	13.041	Down-regulation
TK_Syk_SYK_Y	P52566	ARHGDIB	P43405	SYK	Y24	K21Q	21	Missense	distal	-3	no	17.657	15.980	PhosphoSitePlus	COSMIC	13.041	Down-regulation
TK_Syk_SYK_Y	P52566	ARHGDIB	P43405	SYK	Y146	F141L	141	Missense	distal	-5	no	13.420	13.454	EPSD	COSMIC	13.041	Up-regulation
TK_Syk_SYK_Y	P52566	ARHGDIB	P43405	SYK	Y146	A139E	139	Missense	distal	-7	no	13.420	14.827	EPSD	COSMIC	13.041	Up-regulation
TK_Syk_SYK_Y	P52566	ARHGDIB	P43405	SYK	Y153	F155S	155	Missense	proximal	2	no	14.241	17.215	EPSD	COSMIC	13.041	Up-regulation
TK_Syk_SYK_Y	P52566	ARHGDIB	P43405	SYK	Y153	P158S	158	Missense	distal	5	no	14.241	14.147	EPSD	COSMIC	13.041	Down-regulation
TK_Syk_SYK_Y	P42229	STAT5A	P43405	SYK	Y694	A688D	688	Missense	distal	-6	no	15.261	16.305	PhosphoSitePlus	COSMIC	13.041	Up-regulation
TK_Syk_SYK_Y	P42229	STAT5A	P43405	SYK	Y720	A718D	718	Missense	proximal	-2	no	13.328	17.682	EPSD	COSMIC	13.041	Up-regulation
TK_Syk_SYK_Y	P42229	STAT5A	P43405	SYK	Y720	P725L	725	Missense	distal	5	no	13.328	13.432	EPSD	COSMIC	13.041	Up-regulation
TK_Syk_SYK_Y	P42229	STAT5A	P43405	SYK	Y720	P725H	725	Missense	distal	5	no	13.328	13.372	EPSD	COSMIC	13.041	Up-regulation
TK_Syk_SYK_Y	P42229	STAT5A	P43405	SYK	Y720	D722N	722	Missense	proximal	2	no	13.328	11.239	EPSD	COSMIC	13.041	Loss
TK_Syk_SYK_Y	P22681	CBL	P43405	SYK	Y141	R139T	139	Missense	proximal	-2	no	18.842	19.843	EPSD	COSMIC	13.041	Up-regulation
TK_Syk_SYK_Y	P22681	CBL	P43405	SYK	Y141	Y141C	141	Missense	central	0	yes	18.842	0.000	EPSD	COSMIC	13.041	Loss
TK_Syk_SYK_Y	P22681	CBL	P43405	SYK	Y455	E448Q	448	Missense	distal	-7	no	16.274	15.187	EPSD	COSMIC	13.041	Down-regulation
TK_Syk_SYK_Y	P22681	CBL	P43405	SYK	Y455	D456N	456	Missense	proximal	1	no	16.274	14.956	EPSD	COSMIC	13.041	Down-regulation
TK_Syk_SYK_Y	P22681	CBL	P43405	SYK	Y455	N454D	454	Missense	proximal	-1	no	16.274	17.764	EPSD	COSMIC	13.041	Up-regulation
TK_Syk_SYK_Y	P22681	CBL	P43405	SYK	Y455	D458N	458	Missense	distal	3	no	16.274	17.236	EPSD	COSMIC	13.041	Up-regulation
TK_Syk_SYK_Y	P22681	CBL	P43405	SYK	Y455	G449V	449	Missense	distal	-6	no	16.274	16.138	EPSD	COSMIC	13.041	Down-regulation
TK_Syk_SYK_Y	P22681	CBL	P43405	SYK	Y700	G694D	694	Missense	distal	-6	no	20.796	21.310	PhosphoSitePlus;EPSD	COSMIC	13.041	Up-regulation
TK_Syk_SYK_Y	P22681	CBL	P43405	SYK	Y700	M701V	701	Missense	proximal	1	no	20.796	22.614	PhosphoSitePlus;EPSD	COSMIC	13.041	Up-regulation
TK_Syk_SYK_Y	P22681	CBL	P43405	SYK	Y700	P703L	703	Missense	distal	3	no	20.796	17.062	PhosphoSitePlus;EPSD	COSMIC	13.041	Down-regulation
TK_Syk_SYK_Y	P22681	CBL	P43405	SYK	Y700	S704C	704	Missense	distal	4	no	20.796	19.880	PhosphoSitePlus;EPSD	COSMIC	13.041	Down-regulation
TK_Syk_SYK_Y	P22681	CBL	P43405	SYK	Y700	P707L	707	Missense	distal	7	no	20.796	20.097	PhosphoSitePlus;EPSD	COSMIC	13.041	Down-regulation
TK_Syk_SYK_Y	P22681	CBL	P43405	SYK	Y700	S705C	705	Missense	distal	5	no	20.796	21.012	PhosphoSitePlus;EPSD	COSMIC	13.041	Up-regulation
TK_Syk_SYK_Y	P22681	CBL	P43405	SYK	Y700	R706T	706	Missense	distal	6	no	20.796	20.855	PhosphoSitePlus;EPSD	COSMIC	13.041	Up-regulation
TK_Syk_SYK_Y	P22681	CBL	P43405	SYK	Y731	S728N	728	Missense	distal	-3	no	19.225	19.220	EPSD;PhosphoSitePlus	COSMIC	13.041	Down-regulation
TK_Syk_SYK_Y	P22681	CBL	P43405	SYK	Y731	Y731C	731	Missense	central	0	yes	19.225	0.000	EPSD;PhosphoSitePlus	COSMIC	13.041	Loss
TK_Syk_SYK_Y	P37840	SNCA	P43405	SYK	Y125	A124S	124	Missense	proximal	-1	no	26.604	28.594	EPSD;PhosphoSitePlus	COSMIC	13.041	Up-regulation
TK_Syk_SYK_Y	P37840	SNCA	P43405	SYK	Y125	E130V	130	Missense	distal	5	no	26.604	26.818	EPSD;PhosphoSitePlus	COSMIC	13.041	Up-regulation
TK_Syk_SYK_Y	P37840	SNCA	P43405	SYK	Y125	E130A	130	Missense	distal	5	no	26.604	27.006	EPSD;PhosphoSitePlus	COSMIC	13.041	Up-regulation
TK_Syk_SYK_Y	P37840	SNCA	P43405	SYK	Y125	D121Y	121	Missense	distal	-4	no	26.604	23.428	EPSD;PhosphoSitePlus	COSMIC	13.041	Down-regulation
TK_Syk_SYK_Y	P37840	SNCA	P43405	SYK	Y125	E123K	123	Missense	proximal	-2	no	26.604	24.717	EPSD;PhosphoSitePlus	COSMIC	13.041	Down-regulation
TK_Syk_SYK_Y	P37840	SNCA	P43405	SYK	Y125	D121E	121	Missense	distal	-4	no	26.604	25.327	EPSD;PhosphoSitePlus	COSMIC	13.041	Down-regulation
TK_Syk_SYK_Y	P37840	SNCA	P43405	SYK	Y133	E130V	130	Missense	distal	-3	no	19.060	14.325	PhosphoSitePlus;EPSD	COSMIC	13.041	Down-regulation
TK_Syk_SYK_Y	P37840	SNCA	P43405	SYK	Y133	D135E	135	Missense	proximal	2	no	19.060	17.999	PhosphoSitePlus;EPSD	COSMIC;GDSC;CCLE	13.041	Down-regulation
TK_Syk_SYK_Y	P37840	SNCA	P43405	SYK	Y133	E130A	130	Missense	distal	-3	no	19.060	13.977	PhosphoSitePlus;EPSD	COSMIC	13.041	Down-regulation
TK_Syk_SYK_Y	P37840	SNCA	P43405	SYK	Y136	E130V	130	Missense	distal	-6	no	20.521	19.490	EPSD;PhosphoSitePlus	COSMIC	13.041	Down-regulation
TK_Syk_SYK_Y	P37840	SNCA	P43405	SYK	Y136	D135E	135	Missense	proximal	-1	no	20.521	18.850	EPSD;PhosphoSitePlus	COSMIC;GDSC;CCLE	13.041	Down-regulation
TK_Syk_SYK_Y	P37840	SNCA	P43405	SYK	Y136	E130A	130	Missense	distal	-6	no	20.521	19.095	EPSD;PhosphoSitePlus	COSMIC	13.041	Down-regulation
TK_Syk_SYK_Y	P51452	DUSP3	P43405	SYK	Y23	P26L	26	Missense	distal	3	no	14.301	10.566	EPSD	COSMIC	13.041	Loss
TK_Syk_SYK_Y	P43405	SYK	P43405	SYK	Y28	G33D	33	Missense	distal	5	no	17.283	17.181	EPSD	COSMIC	13.041	Down-regulation
TK_Syk_SYK_Y	P43405	SYK	P43405	SYK	Y28	D27N	27	Missense	proximal	-1	no	17.283	15.793	EPSD	COSMIC	13.041	Down-regulation
TK_Syk_SYK_Y	P43405	SYK	P43405	SYK	Y28	R22Q	22	Missense	distal	-6	no	17.283	17.274	EPSD	COSMIC	13.041	Down-regulation
TK_Syk_SYK_Y	P43405	SYK	P43405	SYK	Y348	V347G	347	Missense	proximal	-1	no	25.445	26.896	EPSD;PhosphoSitePlus	COSMIC	13.041	Up-regulation
TK_Syk_SYK_Y	P43405	SYK	P43405	SYK	Y348	A353V	353	Missense	distal	5	no	25.445	25.257	EPSD;PhosphoSitePlus	COSMIC	13.041	Down-regulation
TK_Syk_SYK_Y	P43405	SYK	P43405	SYK	Y348	P342S	342	Missense	distal	-6	no	25.445	25.911	EPSD;PhosphoSitePlus	COSMIC	13.041	Up-regulation
TK_Syk_SYK_Y	P43405	SYK	P43405	SYK	Y348	M343L	343	Missense	distal	-5	no	25.445	24.827	EPSD;PhosphoSitePlus	COSMIC	13.041	Down-regulation
TK_Syk_SYK_Y	P43405	SYK	P43405	SYK	Y348	Y348D	348	Missense	central	0	yes	25.445	0.000	EPSD;PhosphoSitePlus	COSMIC	13.041	Loss
TK_Syk_SYK_Y	P43405	SYK	P43405	SYK	Y348	Y348H	348	Missense	central	0	yes	25.445	0.000	EPSD;PhosphoSitePlus	COSMIC	13.041	Loss
TK_Syk_SYK_Y	P43405	SYK	P43405	SYK	Y348	V347L	347	Missense	proximal	-1	no	25.445	23.903	EPSD;PhosphoSitePlus	COSMIC	13.041	Down-regulation
TK_Syk_SYK_Y	P43405	SYK	P43405	SYK	Y352	V347G	347	Missense	distal	-5	no	19.592	19.895	PhosphoSitePlus;EPSD	COSMIC	13.041	Up-regulation
TK_Syk_SYK_Y	P43405	SYK	P43405	SYK	Y352	A353V	353	Missense	proximal	1	no	19.592	22.610	PhosphoSitePlus;EPSD	COSMIC	13.041	Up-regulation
TK_Syk_SYK_Y	P43405	SYK	P43405	SYK	Y352	Y348D	348	Missense	distal	-4	no	19.592	22.768	PhosphoSitePlus;EPSD	COSMIC	13.041	Up-regulation
TK_Syk_SYK_Y	P43405	SYK	P43405	SYK	Y352	Y348H	348	Missense	distal	-4	no	19.592	20.453	PhosphoSitePlus;EPSD	COSMIC	13.041	Up-regulation
TK_Syk_SYK_Y	P43405	SYK	P43405	SYK	Y352	V347L	347	Missense	distal	-5	no	19.592	19.022	PhosphoSitePlus;EPSD	COSMIC	13.041	Down-regulation
TK_Syk_SYK_Y	P43405	SYK	P43405	SYK	Y364	V363I	363	Missense	proximal	-1	no	13.434	14.481	EPSD	COSMIC	13.041	Up-regulation
TK_Syk_SYK_Y	P43405	SYK	P43405	SYK	Y364	R367Q	367	Missense	distal	3	no	13.434	14.546	EPSD	COSMIC	13.041	Up-regulation
TK_Syk_SYK_Y	P43405	SYK	P43405	SYK	Y364	L365Q	365	Missense	proximal	1	no	13.434	13.338	EPSD	COSMIC	13.041	Down-regulation
TK_Syk_SYK_Y	P43405	SYK	P43405	SYK	Y525	R520C	520	Missense	distal	-5	no	17.499	17.079	EPSD;PhosphoSitePlus	COSMIC;CCLE	13.041	Down-regulation
TK_Syk_SYK_Y	P43405	SYK	P43405	SYK	Y525	R520H	520	Missense	distal	-5	no	17.499	17.663	EPSD;PhosphoSitePlus	COSMIC	13.041	Up-regulation
TK_Syk_SYK_Y	P43405	SYK	P43405	SYK	Y525	A528T	528	Missense	distal	3	no	17.499	15.297	EPSD;PhosphoSitePlus	COSMIC	13.041	Down-regulation
TK_Syk_SYK_Y	P43405	SYK	P43405	SYK	Y525	E523K	523	Missense	proximal	-2	no	17.499	15.612	EPSD;PhosphoSitePlus	COSMIC	13.041	Down-regulation
TK_Syk_SYK_Y	P43405	SYK	P43405	SYK	Y525	G532E	532	Missense	distal	7	no	17.499	17.975	EPSD;PhosphoSitePlus	COSMIC	13.041	Up-regulation
TK_Syk_SYK_Y	P43405	SYK	P43405	SYK	Y526	R520C	520	Missense	distal	-6	no	17.966	17.553	EPSD;PhosphoSitePlus	COSMIC;CCLE	13.041	Down-regulation
TK_Syk_SYK_Y	P43405	SYK	P43405	SYK	Y526	R520H	520	Missense	distal	-6	no	17.966	17.980	EPSD;PhosphoSitePlus	COSMIC	13.041	Up-regulation
TK_Syk_SYK_Y	P43405	SYK	P43405	SYK	Y526	A528T	528	Missense	proximal	2	no	17.966	19.062	EPSD;PhosphoSitePlus	COSMIC	13.041	Up-regulation
TK_Syk_SYK_Y	P43405	SYK	P43405	SYK	Y526	E523K	523	Missense	distal	-3	no	17.966	15.086	EPSD;PhosphoSitePlus	COSMIC	13.041	Down-regulation
TK_Syk_SYK_Y	P43405	SYK	P43405	SYK	Y526	G532E	532	Missense	distal	6	no	17.966	18.433	EPSD;PhosphoSitePlus	COSMIC	13.041	Up-regulation
TK_Syk_SYK_Y	Q06187	BTK	P43405	SYK	Y241	F242V	242	Missense	proximal	1	no	10.826	15.596	EPSD	COSMIC	13.041	Gain
TK_Syk_SYK_Y	Q06187	BTK	P43405	SYK	Y551	L547Q	547	Missense	distal	-4	no	15.858	17.254	PhosphoSitePlus	COSMIC	13.041	Up-regulation
TK_Syk_SYK_Y	Q06187	BTK	P43405	SYK	Y551	R544W	544	Missense	distal	-7	no	15.858	15.386	PhosphoSitePlus	COSMIC	13.041	Down-regulation
TK_Syk_SYK_Y	Q06187	BTK	P43405	SYK	Y551	S553R	553	Missense	proximal	2	no	15.858	14.161	PhosphoSitePlus	COSMIC	13.041	Down-regulation
TK_Syk_SYK_Y	Q06187	BTK	P43405	SYK	Y551	R544M	544	Missense	distal	-7	no	15.858	15.964	PhosphoSitePlus	COSMIC	13.041	Up-regulation
TK_Syk_SYK_Y	Q06187	BTK	P43405	SYK	Y551	E550K	550	Missense	proximal	-1	no	15.858	13.738	PhosphoSitePlus	COSMIC	13.041	Down-regulation
TK_Syk_SYK_Y	Q8N6F7	GCSAM	P43405	SYK	Y80	Q78H	78	Missense	proximal	-2	no	13.551	14.127	EPSD	COSMIC	13.041	Up-regulation
TK_Syk_SYK_Y	Q8N6F7	GCSAM	P43405	SYK	Y80	E83K	83	Missense	distal	3	no	13.551	11.873	EPSD	COSMIC	13.041	Loss
TK_Syk_SYK_Y	Q8N6F7	GCSAM	P43405	SYK	Y80	D74G	74	Missense	distal	-6	no	13.551	13.037	EPSD	COSMIC	13.041	Loss
TK_Syk_SYK_Y	Q8N6F7	GCSAM	P43405	SYK	Y107	N101D	101	Missense	distal	-6	no	22.062	22.511	EPSD;PhosphoSitePlus	COSMIC	13.041	Up-regulation
TK_Syk_SYK_Y	Q8N6F7	GCSAM	P43405	SYK	Y107	G100W	100	Missense	distal	-7	no	22.062	21.239	EPSD;PhosphoSitePlus	COSMIC	13.041	Down-regulation
TK_Syk_SYK_Y	Q8N6F7	GCSAM	P43405	SYK	Y128	S129L	129	Missense	proximal	1	no	14.817	12.706	PhosphoSitePlus;EPSD	COSMIC	13.041	Loss
TK_Syk_SYK_Y	Q8N6F7	GCSAM	P43405	SYK	Y148	E147G	147	Missense	proximal	-1	no	20.333	18.626	EPSD	COSMIC	13.041	Down-regulation
TK_Syk_SYK_Y	Q8N6F7	GCSAM	P43405	SYK	Y148	E145G	145	Missense	distal	-3	no	20.333	17.676	EPSD	COSMIC	13.041	Down-regulation
TK_Syk_SYK_Y	Q8N6F7	GCSAM	P43405	SYK	Y148	P153T	153	Missense	distal	5	no	20.333	20.360	EPSD	COSMIC;GDSC	13.041	Up-regulation
TK_Syk_SYK_Y	Q8N6F7	GCSAM	P43405	SYK	Y148	A141V	141	Missense	distal	-7	no	20.333	20.967	EPSD	COSMIC	13.041	Up-regulation
TK_Syk_SYK_Y	P10636	MAPT	P43405	SYK	Y514	G521V	521	Missense	distal	7	no	18.664	18.529	EPSD	COSMIC	13.041	Down-regulation
TK_Syk_SYK_Y	P10636	MAPT	P43405	SYK	Y514	G518V	518	Missense	distal	4	no	18.664	18.508	EPSD	COSMIC	13.041	Down-regulation
TK_Syk_SYK_Y	P10636	MAPT	P43405	SYK	Y514	R511C	511	Missense	distal	-3	no	18.664	17.095	EPSD	COSMIC;CCLE	13.041	Down-regulation
TK_Syk_SYK_Y	P10636	MAPT	P43405	SYK	Y514	G509V	509	Missense	distal	-5	no	18.664	18.362	EPSD	COSMIC	13.041	Down-regulation
TK_Syk_SYK_Y	P10636	MAPT	P43405	SYK	Y711	E708D	708	Missense	distal	-3	no	16.864	17.555	EPSD	COSMIC	13.041	Up-regulation
TK_Syk_SYK_Y	P10636	MAPT	P43405	SYK	Y711	G706R	706	Missense	distal	-5	no	16.864	16.517	EPSD	COSMIC	13.041	Down-regulation
TK_Syk_SYK_Y	P10636	MAPT	P43405	SYK	Y711	V710M	710	Missense	proximal	-1	no	16.864	17.893	EPSD	COSMIC	13.041	Up-regulation
TK_Syk_SYK_Y	P10636	MAPT	P43405	SYK	Y711	E708K	708	Missense	distal	-3	no	16.864	13.985	EPSD	COSMIC	13.041	Down-regulation
TK_Syk_SYK_Y	P10636	MAPT	P43405	SYK	Y711	V710A	710	Missense	proximal	-1	no	16.864	17.672	EPSD	COSMIC	13.041	Up-regulation
TK_Syk_SYK_Y	Q13094	LCP2	P43405	SYK	Y113	D112N	112	Missense	proximal	-1	no	26.457	24.967	PhosphoSitePlus;EPSD	COSMIC;GDSC;CCLE	13.041	Down-regulation
TK_Syk_SYK_Y	Q13094	LCP2	P43405	SYK	Y113	D119Y	119	Missense	distal	6	no	26.457	25.966	PhosphoSitePlus;EPSD	COSMIC	13.041	Down-regulation
TK_Syk_SYK_Y	Q13094	LCP2	P43405	SYK	Y113	E109K	109	Missense	distal	-4	no	26.457	25.279	PhosphoSitePlus;EPSD	COSMIC	13.041	Down-regulation
TK_Syk_SYK_Y	Q13094	LCP2	P43405	SYK	Y113	S115I	115	Missense	proximal	2	no	26.457	24.998	PhosphoSitePlus;EPSD	COSMIC	13.041	Down-regulation
TK_Syk_SYK_Y	Q13094	LCP2	P43405	SYK	Y145	P138R	138	Missense	distal	-7	no	28.463	28.322	EPSD	COSMIC;GDSC;CCLE	13.041	Down-regulation
TK_Syk_SYK_Y	Q13094	LCP2	P43405	SYK	Y145	A143T	143	Missense	proximal	-2	no	28.463	29.975	EPSD	COSMIC;GDSC;CCLE	13.041	Up-regulation
TK_Syk_SYK_Y	Q13094	LCP2	P43405	SYK	Y145	A143V	143	Missense	proximal	-2	no	28.463	28.769	EPSD	COSMIC	13.041	Up-regulation
TK_Syk_SYK_Y	Q13094	LCP2	P43405	SYK	Y145	P149T	149	Missense	distal	4	no	28.463	28.331	EPSD	COSMIC	13.041	Down-regulation
TK_Syk_SYK_Y	Q13094	LCP2	P43405	SYK	Y145	P149L	149	Missense	distal	4	no	28.463	27.486	EPSD	COSMIC	13.041	Down-regulation
TK_Syk_SYK_Y	Q13094	LCP2	P43405	SYK	Y173	P167S	167	Missense	distal	-6	no	14.138	14.604	EPSD	COSMIC	13.041	Up-regulation
TK_Syk_SYK_Y	Q13094	LCP2	P43405	SYK	Y173	S171F	171	Missense	proximal	-2	no	14.138	10.772	EPSD	COSMIC	13.041	Loss
TK_Syk_SYK_Y	Q13094	LCP2	P43405	SYK	Y459	Y459N	459	Missense	central	0	yes	14.950	0.000	EPSD	COSMIC	13.041	Loss
TK_Syk_SYK_Y	Q13094	LCP2	P43405	SYK	Y459	P458Q	458	Missense	proximal	-1	no	14.950	14.819	EPSD	COSMIC;GDSC;CCLE	13.041	Down-regulation
TK_Syk_SYK_Y	Q13094	LCP2	P43405	SYK	Y459	M462I	462	Missense	distal	3	no	14.950	12.144	EPSD	COSMIC	13.041	Loss
TK_Syk_SYK_Y	O14986	PIP5K1B	P43405	SYK	Y105	S108F	108	Missense	distal	3	no	16.430	13.055	PhosphoSitePlus	COSMIC	13.041	Down-regulation
STE_STE20_FRAY_STK39_ST	Q13621	SLC12A1	Q9UEW8	STK39	S91	H87Y	87	Missense	distal	-4	no	87.080	82.486	EPSD	COSMIC	61.825	Down-regulation
STE_STE20_FRAY_STK39_ST	Q13621	SLC12A1	Q9UEW8	STK39	S91	Y89H	89	Missense	proximal	-2	no	87.080	89.211	EPSD	COSMIC	61.825	Up-regulation
STE_STE20_FRAY_STK39_ST	Q13621	SLC12A1	Q9UEW8	STK39	T95	Y89H	89	Missense	distal	-6	no	174.299	174.660	EPSD;PhosphoSitePlus	COSMIC	61.825	Up-regulation
STE_STE20_FRAY_STK39_ST	Q13621	SLC12A1	Q9UEW8	STK39	T95	F101V	101	Missense	distal	6	no	174.299	172.897	EPSD;PhosphoSitePlus	COSMIC	61.825	Down-regulation
STE_STE20_FRAY_STK39_ST	Q13621	SLC12A1	Q9UEW8	STK39	T100	F101V	101	Missense	proximal	1	no	176.343	170.843	EPSD;PhosphoSitePlus	COSMIC	61.825	Down-regulation
STE_STE20_FRAY_STK39_ST	Q13621	SLC12A1	Q9UEW8	STK39	T105	I112R	112	Missense	distal	7	no	157.976	157.969	PhosphoSitePlus;EPSD	COSMIC	61.825	Down-regulation
STE_STE20_FRAY_STK39_ST	Q13621	SLC12A1	Q9UEW8	STK39	T105	F101V	101	Missense	distal	-4	no	157.976	152.688	PhosphoSitePlus;EPSD	COSMIC	61.825	Down-regulation
STE_STE20_FRAY_STK39_ST	Q13621	SLC12A1	Q9UEW8	STK39	T118	I112R	112	Missense	distal	-6	no	43.120	68.616	EPSD	COSMIC	61.825	Gain
STE_STE20_FRAY_STK39_ST	Q13621	SLC12A1	Q9UEW8	STK39	S120	G119S	119	Missense	proximal	-1	no	64.347	68.269	EPSD	COSMIC	61.825	Up-regulation
STE_STE20_FRAY_STK39_ST	Q13621	SLC12A1	Q9UEW8	STK39	T145	V152I	152	Missense	distal	7	no	90.681	90.688	EPSD	COSMIC	61.825	Up-regulation
STE_STE20_FRAY_STK39_ST	Q13621	SLC12A1	Q9UEW8	STK39	T882	M886V	886	Missense	distal	4	no	131.807	127.966	EPSD	COSMIC	61.825	Down-regulation
STE_STE20_FRAY_STK39_ST	Q13621	SLC12A1	Q9UEW8	STK39	T882	K876E	876	Missense	distal	-6	no	131.807	131.353	EPSD	COSMIC	61.825	Down-regulation
STE_STE20_FRAY_STK39_ST	Q13621	SLC12A1	Q9UEW8	STK39	T882	K875N	875	Missense	distal	-7	no	131.807	132.378	EPSD	COSMIC	61.825	Up-regulation
STE_STE20_FRAY_STK39_ST	Q13621	SLC12A1	Q9UEW8	STK39	S885	M886V	886	Missense	proximal	1	no	62.500	61.430	EPSD	COSMIC	61.825	Loss
STE_STE20_FRAY_STK39_ST	Q9Y6R1	SLC4A4	Q9UEW8	STK39	T49	R47H	47	Missense	proximal	-2	no	94.930	98.159	EPSD	COSMIC	61.825	Up-regulation
STE_STE20_FRAY_STK39_ST	Q9Y6R1	SLC4A4	Q9UEW8	STK39	T49	R47P	47	Missense	proximal	-2	no	94.930	93.308	EPSD	COSMIC	61.825	Down-regulation
STE_STE20_FRAY_STK39_ST	Q9Y6R1	SLC4A4	Q9UEW8	STK39	T49	R47C	47	Missense	proximal	-2	no	94.930	88.526	EPSD	COSMIC	61.825	Down-regulation
STE_STE20_FRAY_STK39_ST	Q9Y6R1	SLC4A4	Q9UEW8	STK39	T49	E56D	56	Missense	distal	7	no	94.930	94.952	EPSD	COSMIC	61.825	Up-regulation
STE_STE20_FRAY_STK39_ST	Q9Y6R1	SLC4A4	Q9UEW8	STK39	S61	E56D	56	Missense	distal	-5	no	36.912	68.418	EPSD	COSMIC	61.825	Gain
STE_STE20_FRAY_STK39_ST	Q9Y6R1	SLC4A4	Q9UEW8	STK39	S65	E58K	58	Missense	distal	-7	no	113.053	111.370	PhosphoSitePlus	COSMIC	61.825	Down-regulation
STE_STE20_FRAY_STK39_ST	Q9Y6R1	SLC4A4	Q9UEW8	STK39	T207	L209I	209	Missense	proximal	2	no	82.087	99.016	EPSD	COSMIC	61.825	Up-regulation
STE_STE20_FRAY_STK39_ST	Q9Y6R1	SLC4A4	Q9UEW8	STK39	T230	R236C	236	Missense	distal	6	no	77.218	76.008	EPSD	COSMIC	61.825	Down-regulation
STE_STE20_FRAY_STK39_ST	Q9Y6R1	SLC4A4	Q9UEW8	STK39	T230	R236H	236	Missense	distal	6	no	77.218	78.157	EPSD	COSMIC	61.825	Up-regulation
STE_STE20_FRAY_STK39_ST	Q9Y6R1	SLC4A4	Q9UEW8	STK39	T230	R236S	236	Missense	distal	6	no	77.218	76.814	EPSD	COSMIC	61.825	Down-regulation
STE_STE20_FRAY_STK39_ST	Q9Y6R1	SLC4A4	Q9UEW8	STK39	T230	S235G	235	Missense	distal	5	no	77.218	72.231	EPSD	COSMIC	61.825	Down-regulation
STE_STE20_FRAY_STK39_ST	Q9Y6R1	SLC4A4	Q9UEW8	STK39	S235	R236H	236	Missense	proximal	1	no	60.739	74.134	EPSD	COSMIC	61.825	Gain
STE_STE20_FRAY_STK39_ST	Q9Y6R1	SLC4A4	Q9UEW8	STK39	T239	R236C	236	Missense	distal	-3	no	65.823	63.926	EPSD	COSMIC	61.825	Down-regulation
STE_STE20_FRAY_STK39_ST	Q9Y6R1	SLC4A4	Q9UEW8	STK39	T239	R236H	236	Missense	distal	-3	no	65.823	67.889	EPSD	COSMIC	61.825	Up-regulation
STE_STE20_FRAY_STK39_ST	Q9Y6R1	SLC4A4	Q9UEW8	STK39	T239	T239I	239	Missense	central	0	yes	65.823	0.000	EPSD	COSMIC	61.825	Loss
STE_STE20_FRAY_STK39_ST	Q9Y6R1	SLC4A4	Q9UEW8	STK39	T239	R236S	236	Missense	distal	-3	no	65.823	64.607	EPSD	COSMIC	61.825	Down-regulation
STE_STE20_FRAY_STK39_ST	Q9Y6R1	SLC4A4	Q9UEW8	STK39	T239	S235G	235	Missense	distal	-4	no	65.823	56.971	EPSD	COSMIC	61.825	Loss
STE_STE20_FRAY_STK39_ST	Q9Y6R1	SLC4A4	Q9UEW8	STK39	T239	P241S	241	Missense	proximal	2	no	65.823	69.332	EPSD	COSMIC	61.825	Up-regulation
STE_STE20_FRAY_STK39_ST	Q9Y6R1	SLC4A4	Q9UEW8	STK39	S245	T239I	239	Missense	distal	-6	no	86.181	80.696	EPSD	COSMIC	61.825	Down-regulation
STE_STE20_FRAY_STK39_ST	Q9Y6R1	SLC4A4	Q9UEW8	STK39	S245	N252K	252	Missense	distal	7	no	86.181	86.195	EPSD	COSMIC	61.825	Up-regulation
STE_STE20_FRAY_STK39_ST	Q9Y6R1	SLC4A4	Q9UEW8	STK39	S245	P241S	241	Missense	distal	-4	no	86.181	82.933	EPSD	COSMIC	61.825	Down-regulation
STE_STE20_FRAY_STK39_ST	Q9Y6R1	SLC4A4	Q9UEW8	STK39	T249	S255P	255	Missense	distal	6	no	77.158	79.072	EPSD	COSMIC;GDSC;CCLE	61.825	Up-regulation
STE_STE20_FRAY_STK39_ST	Q9Y6R1	SLC4A4	Q9UEW8	STK39	T249	N252K	252	Missense	distal	3	no	77.158	77.781	EPSD	COSMIC	61.825	Up-regulation
STE_STE20_FRAY_STK39_ST	Q9Y6R1	SLC4A4	Q9UEW8	STK39	T249	T254P	254	Missense	distal	5	no	77.158	75.856	EPSD	COSMIC	61.825	Down-regulation
STE_STE20_FRAY_STK39_ST	Q9Y6R1	SLC4A4	Q9UEW8	STK39	T254	S257R	257	Missense	distal	3	no	139.254	140.060	EPSD	COSMIC	61.825	Up-regulation
STE_STE20_FRAY_STK39_ST	Q9Y6R1	SLC4A4	Q9UEW8	STK39	T254	S255P	255	Missense	proximal	1	no	139.254	158.479	EPSD	COSMIC;GDSC;CCLE	61.825	Up-regulation
STE_STE20_FRAY_STK39_ST	Q9Y6R1	SLC4A4	Q9UEW8	STK39	T254	N252K	252	Missense	proximal	-2	no	139.254	138.836	EPSD	COSMIC	61.825	Down-regulation
STE_STE20_FRAY_STK39_ST	Q9Y6R1	SLC4A4	Q9UEW8	STK39	T254	T254P	254	Missense	central	0	yes	139.254	0.000	EPSD	COSMIC	61.825	Loss
STE_STE20_FRAY_STK39_ST	Q9Y6R1	SLC4A4	Q9UEW8	STK39	S255	S257R	257	Missense	proximal	2	no	70.159	56.530	EPSD	COSMIC	61.825	Loss
STE_STE20_FRAY_STK39_ST	Q9Y6R1	SLC4A4	Q9UEW8	STK39	S255	S255P	255	Missense	central	0	yes	70.159	0.000	EPSD	COSMIC;GDSC;CCLE	61.825	Loss
STE_STE20_FRAY_STK39_ST	Q9Y6R1	SLC4A4	Q9UEW8	STK39	S255	N252K	252	Missense	distal	-3	no	70.159	74.496	EPSD	COSMIC	61.825	Up-regulation
STE_STE20_FRAY_STK39_ST	Q9Y6R1	SLC4A4	Q9UEW8	STK39	S255	T254P	254	Missense	proximal	-1	no	70.159	70.111	EPSD	COSMIC	61.825	Down-regulation
STE_STE20_FRAY_STK39_ST	Q9Y6R1	SLC4A4	Q9UEW8	STK39	S1026	K1022E	1022	Missense	distal	-4	no	98.211	80.480	EPSD	COSMIC	61.825	Down-regulation
STE_STE20_FRAY_STK39_ST	P55011	SLC12A2	Q9UEW8	STK39	T203	T207I	207	Missense	distal	4	no	187.879	177.622	EPSD;PhosphoSitePlus	COSMIC;GDSC;CCLE	61.825	Down-regulation
STE_STE20_FRAY_STK39_ST	P55011	SLC12A2	Q9UEW8	STK39	T207	T207I	207	Missense	central	0	yes	156.614	0.000	PhosphoSitePlus;EPSD	COSMIC;GDSC;CCLE	61.825	Loss
STE_STE20_FRAY_STK39_ST	P55011	SLC12A2	Q9UEW8	STK39	T212	T207I	207	Missense	distal	-5	no	177.988	153.572	EPSD;PhosphoSitePlus	COSMIC;GDSC;CCLE	61.825	Down-regulation
STE_STE20_FRAY_STK39_ST	P55011	SLC12A2	Q9UEW8	STK39	T212	T217I	217	Missense	distal	5	no	177.988	174.727	EPSD;PhosphoSitePlus	COSMIC	61.825	Down-regulation
STE_STE20_FRAY_STK39_ST	P55011	SLC12A2	Q9UEW8	STK39	T217	T217I	217	Missense	central	0	yes	170.055	0.000	EPSD	COSMIC	61.825	Loss
STE_STE20_FRAY_STK39_ST	P55011	SLC12A2	Q9UEW8	STK39	T266	V272L	272	Missense	distal	6	no	65.275	63.635	EPSD	COSMIC	61.825	Down-regulation
STE_STE20_FRAY_STK39_ST	P55011	SLC12A2	Q9UEW8	STK39	S944	P945S	945	Missense	proximal	1	no	72.744	53.519	EPSD	COSMIC	61.825	Loss
STE_STE20_FRAY_STK39_ST	P55011	SLC12A2	Q9UEW8	STK39	T947	P945S	945	Missense	proximal	-2	no	81.260	80.029	EPSD	COSMIC	61.825	Down-regulation
STE_STE20_FRAY_STK39_ST	P55011	SLC12A2	Q9UEW8	STK39	T964	D963V	963	Missense	proximal	-1	no	84.888	82.859	EPSD	COSMIC	61.825	Down-regulation
STE_STE20_FRAY_STK39_ST	P55011	SLC12A2	Q9UEW8	STK39	T964	K966I	966	Missense	proximal	2	no	84.888	78.404	EPSD	COSMIC	61.825	Down-regulation
STE_STE20_FRAY_STK39_ST	P55011	SLC12A2	Q9UEW8	STK39	T986	P988Q	988	Missense	proximal	2	no	101.283	98.467	EPSD	COSMIC	61.825	Down-regulation
STE_STE20_FRAY_STK39_ST	Q9H2X9	SLC12A5	Q9UEW8	STK39	S54	G60V	60	Missense	distal	6	no	63.461	64.157	EPSD	COSMIC;GDSC;CCLE	61.825	Up-regulation
STE_STE20_FRAY_STK39_ST	Q9H2X9	SLC12A5	Q9UEW8	STK39	T335	V336A	336	Missense	proximal	1	no	80.046	63.255	EPSD	COSMIC	61.825	Down-regulation
STE_STE20_FRAY_STK39_ST	Q9H2X9	SLC12A5	Q9UEW8	STK39	T335	L328Q	328	Missense	distal	-7	no	80.046	78.583	EPSD	COSMIC	61.825	Down-regulation
STE_STE20_FRAY_STK39_ST	Q9H2X9	SLC12A5	Q9UEW8	STK39	T335	R339W	339	Missense	distal	4	no	80.046	76.446	EPSD	COSMIC	61.825	Down-regulation
STE_STE20_FRAY_STK39_ST	Q9H2X9	SLC12A5	Q9UEW8	STK39	T335	L328M	328	Missense	distal	-7	no	80.046	78.392	EPSD	COSMIC	61.825	Down-regulation
STE_STE20_FRAY_STK39_ST	Q9H2X9	SLC12A5	Q9UEW8	STK39	T945	R951Q	951	Missense	distal	6	no	101.725	101.625	EPSD	COSMIC	61.825	Down-regulation
STE_STE20_FRAY_STK39_ST	Q9H2X9	SLC12A5	Q9UEW8	STK39	T945	R949W	949	Missense	distal	4	no	101.725	98.125	EPSD	COSMIC	61.825	Down-regulation
STE_STE20_FRAY_STK39_ST	Q9H2X9	SLC12A5	Q9UEW8	STK39	T1030	D1023Y	1023	Missense	distal	-7	no	116.173	117.536	EPSD	COSMIC	61.825	Up-regulation
STE_STE20_FRAY_STK39_ST	Q9H2X9	SLC12A5	Q9UEW8	STK39	S1045	S1045P	1045	Missense	central	0	yes	75.757	0.000	EPSD	COSMIC	61.825	Loss
STE_STE20_FRAY_STK39_ST	Q9H2X9	SLC12A5	Q9UEW8	STK39	S1045	S1049C	1049	Missense	distal	4	no	75.757	76.072	EPSD	COSMIC	61.825	Up-regulation
STE_STE20_FRAY_STK39_ST	Q9Y666	SLC12A7	Q9UEW8	STK39	S96	V100L	100	Missense	distal	4	no	71.876	64.240	EPSD	COSMIC	61.825	Down-regulation
STE_STE20_FRAY_STK39_ST	Q9Y666	SLC12A7	Q9UEW8	STK39	T958	D955N	955	Missense	distal	-3	no	81.330	79.953	EPSD	COSMIC	61.825	Down-regulation
STE_STE20_FRAY_STK39_ST	Q9Y666	SLC12A7	Q9UEW8	STK39	T958	A964T	964	Missense	distal	6	no	81.330	81.548	EPSD	COSMIC	61.825	Up-regulation
STE_STE20_FRAY_STK39_ST	Q9Y666	SLC12A7	Q9UEW8	STK39	T958	T962I	962	Missense	distal	4	no	81.330	71.073	EPSD	COSMIC;GDSC;CCLE	61.825	Down-regulation
STE_STE20_FRAY_STK39_ST	Q9Y666	SLC12A7	Q9UEW8	STK39	S960	D955N	955	Missense	distal	-5	no	72.283	56.204	EPSD	COSMIC	61.825	Loss
STE_STE20_FRAY_STK39_ST	Q9Y666	SLC12A7	Q9UEW8	STK39	S960	A964T	964	Missense	distal	4	no	72.283	87.759	EPSD	COSMIC	61.825	Up-regulation
STE_STE20_FRAY_STK39_ST	Q9Y666	SLC12A7	Q9UEW8	STK39	S960	T962I	962	Missense	proximal	2	no	72.283	63.894	EPSD	COSMIC;GDSC;CCLE	61.825	Down-regulation
STE_STE20_FRAY_STK39_ST	Q9Y666	SLC12A7	Q9UEW8	STK39	T962	D955N	955	Missense	distal	-7	no	71.316	72.021	EPSD	COSMIC	61.825	Up-regulation
STE_STE20_FRAY_STK39_ST	Q9Y666	SLC12A7	Q9UEW8	STK39	T962	A964T	964	Missense	proximal	2	no	71.316	89.925	EPSD	COSMIC	61.825	Up-regulation
STE_STE20_FRAY_STK39_ST	Q9Y666	SLC12A7	Q9UEW8	STK39	T962	T962I	962	Missense	central	0	yes	71.316	0.000	EPSD	COSMIC;GDSC;CCLE	61.825	Loss
STE_STE20_FRAY_STK39_ST	Q9Y666	SLC12A7	Q9UEW8	STK39	T980	I987M	987	Missense	distal	7	no	144.176	144.175	EPSD;PhosphoSitePlus	COSMIC	61.825	Down-regulation
STE_STE20_FRAY_STK39_ST	Q9Y666	SLC12A7	Q9UEW8	STK39	T982	I987M	987	Missense	distal	5	no	67.085	64.176	EPSD	COSMIC	61.825	Down-regulation
STE_STE20_FRAY_STK39_ST	Q9UHW9	SLC12A6	Q9UEW8	STK39	S29	P33L	33	Missense	distal	4	no	73.880	68.209	EPSD	COSMIC;CCLE	61.825	Down-regulation
STE_STE20_FRAY_STK39_ST	Q9UHW9	SLC12A6	Q9UEW8	STK39	S29	P33S	33	Missense	distal	4	no	73.880	72.862	EPSD	COSMIC	61.825	Down-regulation
STE_STE20_FRAY_STK39_ST	Q9UHW9	SLC12A6	Q9UEW8	STK39	S29	S29P	29	Missense	central	0	yes	73.880	0.000	EPSD	COSMIC;CCLE	61.825	Loss
STE_STE20_FRAY_STK39_ST	Q9UHW9	SLC12A6	Q9UEW8	STK39	S29	S32C	32	Missense	distal	3	no	73.880	72.712	EPSD	COSMIC	61.825	Down-regulation
STE_STE20_FRAY_STK39_ST	Q9UHW9	SLC12A6	Q9UEW8	STK39	T54	M60I	60	Missense	distal	6	no	71.164	70.597	EPSD	COSMIC	61.825	Down-regulation
STE_STE20_FRAY_STK39_ST	Q9UHW9	SLC12A6	Q9UEW8	STK39	T54	S55F	55	Missense	proximal	1	no	71.164	85.146	EPSD	COSMIC	61.825	Up-regulation
STE_STE20_FRAY_STK39_ST	Q9UHW9	SLC12A6	Q9UEW8	STK39	T54	S55Y	55	Missense	proximal	1	no	71.164	84.003	EPSD	COSMIC	61.825	Up-regulation
STE_STE20_FRAY_STK39_ST	Q9UHW9	SLC12A6	Q9UEW8	STK39	T68	S64F	64	Missense	distal	-4	no	72.709	71.159	EPSD	COSMIC	61.825	Down-regulation
STE_STE20_FRAY_STK39_ST	Q9UHW9	SLC12A6	Q9UEW8	STK39	T68	M63K	63	Missense	distal	-5	no	72.709	84.804	EPSD	COSMIC	61.825	Up-regulation
STE_STE20_FRAY_STK39_ST	Q9UHW9	SLC12A6	Q9UEW8	STK39	T68	S64Y	64	Missense	distal	-4	no	72.709	76.003	EPSD	COSMIC	61.825	Up-regulation
STE_STE20_FRAY_STK39_ST	Q9UHW9	SLC12A6	Q9UEW8	STK39	T72	P78H	78	Missense	distal	6	no	81.995	81.423	EPSD	COSMIC	61.825	Down-regulation
STE_STE20_FRAY_STK39_ST	Q9UHW9	SLC12A6	Q9UEW8	STK39	S96	I97V	97	Missense	proximal	1	no	125.264	124.972	EPSD;PhosphoSitePlus	COSMIC	61.825	Down-regulation
STE_STE20_FRAY_STK39_ST	Q9UHW9	SLC12A6	Q9UEW8	STK39	S96	G99W	99	Missense	distal	3	no	125.264	125.561	EPSD;PhosphoSitePlus	COSMIC	61.825	Up-regulation
STE_STE20_FRAY_STK39_ST	Q9UHW9	SLC12A6	Q9UEW8	STK39	S96	G99A	99	Missense	distal	3	no	125.264	125.619	EPSD;PhosphoSitePlus	COSMIC	61.825	Up-regulation
STE_STE20_FRAY_STK39_ST	Q9UHW9	SLC12A6	Q9UEW8	STK39	S147	R152H	152	Missense	distal	5	no	49.464	69.324	EPSD	COSMIC	61.825	Gain
STE_STE20_FRAY_STK39_ST	Q9UHW9	SLC12A6	Q9UEW8	STK39	S147	L149I	149	Missense	proximal	2	no	49.464	66.393	EPSD	COSMIC	61.825	Gain
STE_STE20_FRAY_STK39_ST	Q9UHW9	SLC12A6	Q9UEW8	STK39	S147	R143H	143	Missense	distal	-4	no	49.464	62.692	EPSD	COSMIC	61.825	Gain
STE_STE20_FRAY_STK39_ST	Q9UHW9	SLC12A6	Q9UEW8	STK39	T157	R152S	152	Missense	distal	-5	no	55.144	73.468	EPSD	COSMIC	61.825	Gain
STE_STE20_FRAY_STK39_ST	Q9UHW9	SLC12A6	Q9UEW8	STK39	T157	R152H	152	Missense	distal	-5	no	55.144	90.289	EPSD	COSMIC	61.825	Gain
STE_STE20_FRAY_STK39_ST	Q9UHW9	SLC12A6	Q9UEW8	STK39	T160	E165K	165	Missense	distal	5	no	133.263	139.798	EPSD;PhosphoSitePlus	COSMIC	61.825	Up-regulation
STE_STE20_FRAY_STK39_ST	Q9UHW9	SLC12A6	Q9UEW8	STK39	T187	M189I	189	Missense	proximal	2	no	72.686	75.702	EPSD	COSMIC	61.825	Up-regulation
STE_STE20_FRAY_STK39_ST	Q9UHW9	SLC12A6	Q9UEW8	STK39	T187	P183L	183	Missense	distal	-4	no	72.686	51.321	EPSD	COSMIC	61.825	Loss
STE_STE20_FRAY_STK39_ST	Q9UHW9	SLC12A6	Q9UEW8	STK39	T187	T180I	180	Missense	distal	-7	no	72.686	73.540	EPSD	COSMIC	61.825	Up-regulation
STE_STE20_FRAY_STK39_ST	Q9UHW9	SLC12A6	Q9UEW8	STK39	T1028	R1026Q	1026	Missense	proximal	-2	no	102.031	99.389	EPSD	COSMIC	61.825	Down-regulation
STE_STE20_FRAY_STK39_ST	Q9UHW9	SLC12A6	Q9UEW8	STK39	T1028	D1033N	1033	Missense	distal	5	no	102.031	89.857	EPSD	COSMIC	61.825	Down-regulation
STE_STE20_FRAY_STK39_ST	Q9UHW9	SLC12A6	Q9UEW8	STK39	T1028	R1026L	1026	Missense	proximal	-2	no	102.031	88.666	EPSD	COSMIC	61.825	Down-regulation
STE_STE20_FRAY_STK39_ST	Q9UHW9	SLC12A6	Q9UEW8	STK39	T1038	D1033N	1033	Missense	distal	-5	no	93.526	77.447	EPSD	COSMIC	61.825	Down-regulation
STE_STE20_FRAY_STK39_ST	Q9UHW9	SLC12A6	Q9UEW8	STK39	T1040	D1033N	1033	Missense	distal	-7	no	97.170	97.875	EPSD	COSMIC	61.825	Up-regulation
STE_STE20_FRAY_STK39_ST	Q9UHW9	SLC12A6	Q9UEW8	STK39	T1086	S1079F	1079	Missense	distal	-7	no	66.052	67.011	EPSD	COSMIC	61.825	Up-regulation
STE_STE20_FRAY_STK39_ST	Q9UHW9	SLC12A6	Q9UEW8	STK39	T1086	N1091K	1091	Missense	distal	5	no	66.052	70.513	EPSD	COSMIC	61.825	Up-regulation
STE_STE20_FRAY_STK39_ST	Q9UP95	SLC12A4	Q9UEW8	STK39	T5	V7G	7	Missense	proximal	2	no	86.231	87.952	EPSD;PhosphoSitePlus	COSMIC	61.825	Up-regulation
STE_STE20_FRAY_STK39_ST	Q9UP95	SLC12A4	Q9UEW8	STK39	T93	H99N	99	Missense	distal	6	no	102.478	100.908	EPSD	COSMIC	61.825	Down-regulation
STE_STE20_FRAY_STK39_ST	Q9UP95	SLC12A4	Q9UEW8	STK39	T93	V87L	87	Missense	distal	-6	no	102.478	104.645	EPSD	COSMIC	61.825	Up-regulation
STE_STE20_FRAY_STK39_ST	Q9UP95	SLC12A4	Q9UEW8	STK39	S973	E969K	969	Missense	distal	-4	no	44.689	62.420	EPSD	COSMIC	61.825	Gain
STE_STE20_FRAY_STK39_ST	Q9UP95	SLC12A4	Q9UEW8	STK39	T983	Y989C	989	Missense	distal	6	no	176.865	175.104	PhosphoSitePlus;EPSD	COSMIC	61.825	Down-regulation
STE_STE20_FRAY_STK39_ST	Q9UP95	SLC12A4	Q9UEW8	STK39	T983	D987N	987	Missense	distal	4	no	176.865	173.766	PhosphoSitePlus;EPSD	COSMIC	61.825	Down-regulation
STE_STE20_FRAY_STK39_ST	Q9UP95	SLC12A4	Q9UEW8	STK39	T983	R986L	986	Missense	distal	3	no	176.865	174.124	PhosphoSitePlus;EPSD	COSMIC	61.825	Down-regulation
STE_STE20_FRAY_STK39_ST	Q9UP95	SLC12A4	Q9UEW8	STK39	T985	Y989C	989	Missense	distal	4	no	90.002	87.137	EPSD	COSMIC	61.825	Down-regulation
STE_STE20_FRAY_STK39_ST	Q9UP95	SLC12A4	Q9UEW8	STK39	T985	D987N	987	Missense	proximal	2	no	90.002	79.044	EPSD	COSMIC	61.825	Down-regulation
STE_STE20_FRAY_STK39_ST	Q9UP95	SLC12A4	Q9UEW8	STK39	T985	R986L	986	Missense	proximal	1	no	90.002	82.853	EPSD	COSMIC	61.825	Down-regulation
STE_STE20_FRAY_STK39_ST	Q9UP95	SLC12A4	Q9UEW8	STK39	T991	Y989C	989	Missense	proximal	-2	no	98.365	90.862	EPSD	COSMIC	61.825	Down-regulation
STE_STE20_FRAY_STK39_ST	Q9UP95	SLC12A4	Q9UEW8	STK39	T991	D995A	995	Missense	distal	4	no	98.365	80.529	EPSD	COSMIC	61.825	Down-regulation
STE_STE20_FRAY_STK39_ST	Q9UP95	SLC12A4	Q9UEW8	STK39	T991	D987N	987	Missense	distal	-4	no	98.365	91.802	EPSD	COSMIC	61.825	Down-regulation
STE_STE20_FRAY_STK39_ST	Q9UP95	SLC12A4	Q9UEW8	STK39	T991	R986L	986	Missense	distal	-5	no	98.365	88.415	EPSD	COSMIC	61.825	Down-regulation
STE_STE20_FRAY_STK39_ST	Q9UP95	SLC12A4	Q9UEW8	STK39	T993	Y989C	989	Missense	distal	-4	no	106.793	94.100	EPSD	COSMIC	61.825	Down-regulation
STE_STE20_FRAY_STK39_ST	Q9UP95	SLC12A4	Q9UEW8	STK39	T993	D995A	995	Missense	proximal	2	no	106.793	84.095	EPSD	COSMIC	61.825	Down-regulation
STE_STE20_FRAY_STK39_ST	Q9UP95	SLC12A4	Q9UEW8	STK39	T993	D987N	987	Missense	distal	-6	no	106.793	116.423	EPSD	COSMIC	61.825	Up-regulation
STE_STE20_FRAY_STK39_ST	Q9UP95	SLC12A4	Q9UEW8	STK39	T993	R986L	986	Missense	distal	-7	no	106.793	108.546	EPSD	COSMIC	61.825	Up-regulation
STE_STE20_FRAY_STK39_ST	Q9UP95	SLC12A4	Q9UEW8	STK39	T1021	R1018H	1018	Missense	distal	-3	no	60.673	62.739	EPSD	COSMIC;GDSC;CCLE	61.825	Gain
STE_STE20_FRAY_STK39_ST	P55017	SLC12A3	Q9UEW8	STK39	T14	T9M	9	Missense	distal	-5	no	75.566	47.192	EPSD	COSMIC	61.825	Loss
STE_STE20_FRAY_STK39_ST	P55017	SLC12A3	Q9UEW8	STK39	T14	F20L	20	Missense	distal	6	no	75.566	72.522	EPSD	COSMIC	61.825	Down-regulation
STE_STE20_FRAY_STK39_ST	P55017	SLC12A3	Q9UEW8	STK39	T14	G18E	18	Missense	distal	4	no	75.566	81.893	EPSD	COSMIC	61.825	Up-regulation
STE_STE20_FRAY_STK39_ST	P55017	SLC12A3	Q9UEW8	STK39	T46	H41P	41	Missense	distal	-5	no	151.632	131.119	EPSD;PhosphoSitePlus	COSMIC	61.825	Down-regulation
STE_STE20_FRAY_STK39_ST	P55017	SLC12A3	Q9UEW8	STK39	T46	C52R	52	Missense	distal	6	no	151.632	152.842	EPSD;PhosphoSitePlus	COSMIC	61.825	Up-regulation
STE_STE20_FRAY_STK39_ST	P55017	SLC12A3	Q9UEW8	STK39	T50	C52R	52	Missense	proximal	2	no	82.847	72.963	EPSD	COSMIC	61.825	Down-regulation
STE_STE20_FRAY_STK39_ST	P55017	SLC12A3	Q9UEW8	STK39	T50	R54H	54	Missense	distal	4	no	82.847	87.869	EPSD	COSMIC;GDSC;CCLE	61.825	Up-regulation
STE_STE20_FRAY_STK39_ST	P55017	SLC12A3	Q9UEW8	STK39	T55	C52R	52	Missense	distal	-3	no	164.354	166.250	EPSD;PhosphoSitePlus	COSMIC	61.825	Up-regulation
STE_STE20_FRAY_STK39_ST	P55017	SLC12A3	Q9UEW8	STK39	T55	R54H	54	Missense	proximal	-1	no	164.354	159.294	EPSD;PhosphoSitePlus	COSMIC;GDSC;CCLE	61.825	Down-regulation
STE_STE20_FRAY_STK39_ST	P55017	SLC12A3	Q9UEW8	STK39	T60	R54H	54	Missense	distal	-6	no	159.444	148.886	PhosphoSitePlus;EPSD	COSMIC;GDSC;CCLE	61.825	Down-regulation
STE_STE20_FRAY_STK39_ST	P55017	SLC12A3	Q9UEW8	STK39	T74	K81R	81	Missense	distal	7	no	101.488	101.466	EPSD	COSMIC	61.825	Down-regulation
STE_STE20_FRAY_STK39_ST	P55017	SLC12A3	Q9UEW8	STK39	T85	S91F	91	Missense	distal	6	no	60.708	61.873	EPSD	COSMIC	61.825	Gain
STE_STE20_FRAY_STK39_ST	P55017	SLC12A3	Q9UEW8	STK39	T753	V754L	754	Missense	proximal	1	no	63.580	48.831	EPSD	COSMIC	61.825	Loss
STE_STE20_FRAY_STK39_ST	P55017	SLC12A3	Q9UEW8	STK39	T753	A749D	749	Missense	distal	-4	no	63.580	77.559	EPSD	COSMIC	61.825	Up-regulation
STE_STE20_FRAY_STK39_ST	P55017	SLC12A3	Q9UEW8	STK39	T753	E755K	755	Missense	proximal	2	no	63.580	72.863	EPSD	COSMIC	61.825	Up-regulation
STE_STE20_FRAY_STK39_ST	P55017	SLC12A3	Q9UEW8	STK39	T753	A749T	749	Missense	distal	-4	no	63.580	74.427	EPSD	COSMIC	61.825	Up-regulation
TKL_IRAK_IRAK1_ST	Q96FA3	PELI1	P51617	IRAK1	S70	A66V	66	Missense	distal	-4	no	121.890	121.782	EPSD;PhosphoSitePlus	COSMIC;CCLE	67.712	Down-regulation
TKL_IRAK_IRAK1_ST	Q96FA3	PELI1	P51617	IRAK1	S70	P63L	63	Missense	distal	-7	no	121.890	128.731	EPSD;PhosphoSitePlus	COSMIC	67.712	Up-regulation
TKL_IRAK_IRAK1_ST	Q96FA3	PELI1	P51617	IRAK1	T86	E90D	90	Missense	distal	4	no	110.913	110.792	EPSD;PhosphoSitePlus	COSMIC	67.712	Down-regulation
TKL_IRAK_IRAK1_ST	Q96FA3	PELI1	P51617	IRAK1	S125	S123R	123	Missense	proximal	-2	no	117.669	117.837	EPSD;PhosphoSitePlus	COSMIC	67.712	Up-regulation
TKL_IRAK_IRAK1_ST	Q96FA3	PELI1	P51617	IRAK1	T127	S123R	123	Missense	distal	-4	no	125.413	126.849	EPSD;PhosphoSitePlus	COSMIC	67.712	Up-regulation
TKL_IRAK_IRAK1_ST	Q96FA3	PELI1	P51617	IRAK1	S293	R296K	296	Missense	distal	3	no	116.243	113.118	EPSD;PhosphoSitePlus	COSMIC	67.712	Down-regulation
TKL_IRAK_IRAK1_ST	P51617	IRAK1	P51617	IRAK1	T113	S110P	110	Missense	distal	-3	no	81.507	81.734	EPSD	COSMIC	67.712	Up-regulation
TKL_IRAK_IRAK1_ST	P51617	IRAK1	P51617	IRAK1	T113	T114A	114	Missense	proximal	1	no	81.507	82.584	EPSD	COSMIC	67.712	Up-regulation
TKL_IRAK_IRAK1_ST	P51617	IRAK1	P51617	IRAK1	S119	I121L	121	Missense	proximal	2	no	77.258	70.584	EPSD	COSMIC	67.712	Down-regulation
TKL_IRAK_IRAK1_ST	P51617	IRAK1	P51617	IRAK1	S119	T114A	114	Missense	distal	-5	no	77.258	71.771	EPSD	COSMIC	67.712	Down-regulation
TKL_IRAK_IRAK1_ST	P51617	IRAK1	P51617	IRAK1	S131	R133W	133	Missense	proximal	2	no	80.572	68.190	EPSD	COSMIC;CCLE	67.712	Down-regulation
TKL_IRAK_IRAK1_ST	P51617	IRAK1	P51617	IRAK1	S131	P136Q	136	Missense	distal	5	no	80.572	80.027	EPSD	COSMIC	67.712	Down-regulation
TKL_IRAK_IRAK1_ST	P51617	IRAK1	P51617	IRAK1	S131	R133L	133	Missense	proximal	2	no	80.572	71.798	EPSD	COSMIC	67.712	Down-regulation
TKL_IRAK_IRAK1_ST	P51617	IRAK1	P51617	IRAK1	T209	S213L	213	Missense	distal	4	no	117.499	113.826	EPSD;PhosphoSitePlus	COSMIC	67.712	Down-regulation
TKL_IRAK_IRAK1_ST	P51617	IRAK1	P51617	IRAK1	T209	S206P	206	Missense	distal	-3	no	117.499	117.726	EPSD;PhosphoSitePlus	COSMIC	67.712	Up-regulation
TKL_IRAK_IRAK1_ST	P51617	IRAK1	P51617	IRAK1	T209	H210Q	210	Missense	proximal	1	no	117.499	117.228	EPSD;PhosphoSitePlus	COSMIC	67.712	Down-regulation
TKL_IRAK_IRAK1_ST	P51617	IRAK1	P51617	IRAK1	T209	H210R	210	Missense	proximal	1	no	117.499	116.956	EPSD;PhosphoSitePlus	COSMIC	67.712	Down-regulation
TKL_IRAK_IRAK1_ST	P51617	IRAK1	P51617	IRAK1	T209	C203S	203	Missense	distal	-6	no	117.499	113.979	EPSD;PhosphoSitePlus	COSMIC;GDSC	67.712	Down-regulation
TKL_IRAK_IRAK1_ST	P51617	IRAK1	P51617	IRAK1	T381	R380W	380	Missense	proximal	-1	no	80.256	82.886	EPSD	COSMIC	67.712	Up-regulation
TKL_IRAK_IRAK1_ST	P51617	IRAK1	P51617	IRAK1	T387	E393K	393	Missense	distal	6	no	112.578	115.546	PhosphoSitePlus;EPSD	COSMIC;GDSC;CCLE	67.712	Up-regulation
TKL_IRAK_IRAK1_ST	P51617	IRAK1	P51617	IRAK1	T387	P392L	392	Missense	distal	5	no	112.578	112.934	PhosphoSitePlus;EPSD	COSMIC	67.712	Up-regulation
TKL_IRAK_IRAK1_ST	P51617	IRAK1	P51617	IRAK1	T387	R380W	380	Missense	distal	-7	no	112.578	113.802	PhosphoSitePlus;EPSD	COSMIC	67.712	Up-regulation
TKL_IRAK_IRAK1_ST	P51617	IRAK1	P51617	IRAK1	S607	P614S	614	Missense	distal	7	no	64.828	72.681	EPSD	COSMIC	67.712	Gain
TKL_IRAK_IRAK1_ST	P51617	IRAK1	P51617	IRAK1	S607	R600H	600	Missense	distal	-7	no	64.828	67.745	EPSD	COSMIC	67.712	Gain
TKL_IRAK_IRAK1_ST	Q9HAT8	PELI2	P51617	IRAK1	S78	S72N	72	Missense	distal	-6	no	72.191	67.442	EPSD	COSMIC	67.712	Loss
TKL_IRAK_IRAK1_ST	Q9HAT8	PELI2	P51617	IRAK1	S78	S80F	80	Missense	proximal	2	no	72.191	59.555	EPSD	COSMIC	67.712	Loss
TKL_IRAK_IRAK1_ST	Q9HAT8	PELI2	P51617	IRAK1	S78	I79V	79	Missense	proximal	1	no	72.191	70.471	EPSD	COSMIC	67.712	Down-regulation
TKL_IRAK_IRAK1_ST	Q9HAT8	PELI2	P51617	IRAK1	S80	S80F	80	Missense	central	0	yes	91.169	0.000	EPSD	COSMIC	67.712	Loss
TKL_IRAK_IRAK1_ST	Q9HAT8	PELI2	P51617	IRAK1	S80	I79V	79	Missense	proximal	-1	no	91.169	86.994	EPSD	COSMIC	67.712	Down-regulation
TKL_IRAK_IRAK1_ST	Q9HAT8	PELI2	P51617	IRAK1	T82	V89L	89	Missense	distal	7	no	113.740	102.843	EPSD	COSMIC	67.712	Down-regulation
TKL_IRAK_IRAK1_ST	Q9HAT8	PELI2	P51617	IRAK1	T82	S80F	80	Missense	proximal	-2	no	113.740	113.559	EPSD	COSMIC	67.712	Down-regulation
TKL_IRAK_IRAK1_ST	Q9HAT8	PELI2	P51617	IRAK1	T82	I79V	79	Missense	distal	-3	no	113.740	113.518	EPSD	COSMIC	67.712	Down-regulation
TKL_IRAK_IRAK1_ST	Q9HAT8	PELI2	P51617	IRAK1	S84	V89L	89	Missense	distal	5	no	75.820	77.581	EPSD	COSMIC	67.712	Up-regulation
TKL_IRAK_IRAK1_ST	Q9HAT8	PELI2	P51617	IRAK1	S84	S80F	80	Missense	distal	-4	no	75.820	68.811	EPSD	COSMIC	67.712	Down-regulation
TKL_IRAK_IRAK1_ST	Q9HAT8	PELI2	P51617	IRAK1	S84	I79V	79	Missense	distal	-5	no	75.820	70.556	EPSD	COSMIC	67.712	Down-regulation
TKL_IRAK_IRAK1_ST	Q9HAT8	PELI2	P51617	IRAK1	T88	V89L	89	Missense	proximal	1	no	85.663	87.535	EPSD	COSMIC	67.712	Up-regulation
TKL_IRAK_IRAK1_ST	Q9HAT8	PELI2	P51617	IRAK1	S235	E236K	236	Missense	proximal	1	no	78.469	79.606	EPSD	COSMIC	67.712	Up-regulation
TKL_IRAK_IRAK1_ST	Q9HAT8	PELI2	P51617	IRAK1	T237	E236K	236	Missense	proximal	-1	no	68.495	69.995	EPSD	COSMIC	67.712	Up-regulation
TKL_IRAK_IRAK1_ST	Q9HAT8	PELI2	P51617	IRAK1	T290	I296N	296	Missense	distal	6	no	135.720	125.682	PhosphoSitePlus	COSMIC	67.712	Down-regulation
TKL_IRAK_IRAK1_ST	Q9HAT8	PELI2	P51617	IRAK1	S295	I296N	296	Missense	proximal	1	no	95.219	95.772	EPSD	COSMIC	67.712	Up-regulation
TKL_IRAK_IRAK1_ST	P40763	STAT3	P51617	IRAK1	T133	P132S	132	Missense	proximal	-1	no	81.042	77.987	EPSD	COSMIC	67.712	Down-regulation
TKL_IRAK_IRAK1_ST	P40763	STAT3	P51617	IRAK1	T133	G126E	126	Missense	distal	-7	no	81.042	79.295	EPSD	COSMIC	67.712	Down-regulation
TKL_IRAK_IRAK1_ST	P40763	STAT3	P51617	IRAK1	T133	G127C	127	Missense	distal	-6	no	81.042	96.693	EPSD	COSMIC	67.712	Up-regulation
TKL_IRAK_IRAK1_ST	P40763	STAT3	P51617	IRAK1	T133	T138M	138	Missense	distal	5	no	81.042	81.532	EPSD	COSMIC	67.712	Up-regulation
TKL_IRAK_IRAK1_ST	P40763	STAT3	P51617	IRAK1	T133	A129P	129	Missense	distal	-4	no	81.042	73.557	EPSD	COSMIC	67.712	Down-regulation
TKL_IRAK_IRAK1_ST	P40763	STAT3	P51617	IRAK1	T545	W546L	546	Missense	proximal	1	no	71.747	72.533	EPSD	COSMIC	67.712	Up-regulation
TKL_IRAK_IRAK1_ST	P40763	STAT3	P51617	IRAK1	T545	C550R	550	Missense	distal	5	no	71.747	70.446	EPSD	COSMIC	67.712	Down-regulation
TKL_IRAK_IRAK1_ST	P40763	STAT3	P51617	IRAK1	T545	G541R	541	Missense	distal	-4	no	71.747	84.290	EPSD	COSMIC	67.712	Up-regulation
TKL_IRAK_IRAK1_ST	P40763	STAT3	P51617	IRAK1	T632	K626N	626	Missense	distal	-6	no	75.720	76.146	EPSD	COSMIC	67.712	Up-regulation
TKL_IRAK_IRAK1_ST	P40763	STAT3	P51617	IRAK1	T632	E638Q	638	Missense	distal	6	no	75.720	80.473	EPSD	COSMIC	67.712	Up-regulation
TKL_IRAK_IRAK1_ST	P40763	STAT3	P51617	IRAK1	S727	D723N	723	Missense	distal	-4	no	112.460	108.639	PhosphoSitePlus	COSMIC	67.712	Down-regulation
CMGC_CDKL_CDKL5_ST	Q9HCJ2	LRRC4C	O76039	CDKL5	S173	R175C	175	Missense	proximal	2	no	4.176	4.187	EPSD	COSMIC;CCLE	2.968	Up-regulation
CMGC_CDKL_CDKL5_ST	Q9HCJ2	LRRC4C	O76039	CDKL5	S173	L177Q	177	Missense	distal	4	no	4.176	4.180	EPSD	COSMIC	2.968	Up-regulation
CMGC_CDKL_CDKL5_ST	Q9HCJ2	LRRC4C	O76039	CDKL5	S173	S173F	173	Missense	central	0	yes	4.176	0.000	EPSD	COSMIC	2.968	Loss
CMGC_CDKL_CDKL5_ST	Q9HCJ2	LRRC4C	O76039	CDKL5	S383	P389S	389	Missense	distal	6	no	2.790	3.161	EPSD	COSMIC	2.968	Gain
CMGC_CDKL_CDKL5_ST	Q9HCJ2	LRRC4C	O76039	CDKL5	S631	P624S	624	Missense	distal	-7	no	6.210	5.324	PhosphoSitePlus	COSMIC	2.968	Down-regulation
CMGC_CDKL_CDKL5_ST	Q9HCJ2	LRRC4C	O76039	CDKL5	S631	L625F	625	Missense	distal	-6	no	6.210	6.215	PhosphoSitePlus	COSMIC	2.968	Up-regulation
CMGC_CDKL_CDKL5_ST	Q9HCJ2	LRRC4C	O76039	CDKL5	S631	I627F	627	Missense	distal	-4	no	6.210	6.192	PhosphoSitePlus	COSMIC	2.968	Down-regulation
CMGC_CDKL_CDKL5_ST	Q9UPN4	CEP131	O76039	CDKL5	T23	P27L	27	Missense	distal	4	no	3.308	3.346	EPSD	COSMIC	2.968	Up-regulation
CMGC_CDKL_CDKL5_ST	Q9UPN4	CEP131	O76039	CDKL5	T23	S30Y	30	Missense	distal	7	no	3.308	3.365	EPSD	COSMIC	2.968	Up-regulation
CMGC_CDKL_CDKL5_ST	Q9UPN4	CEP131	O76039	CDKL5	S30	R31W	31	Missense	proximal	1	no	3.354	3.345	EPSD	COSMIC	2.968	Down-regulation
CMGC_CDKL_CDKL5_ST	Q9UPN4	CEP131	O76039	CDKL5	S30	P27L	27	Missense	distal	-3	no	3.354	3.649	EPSD	COSMIC	2.968	Up-regulation
CMGC_CDKL_CDKL5_ST	Q9UPN4	CEP131	O76039	CDKL5	S30	R32H	32	Missense	proximal	2	no	3.354	3.334	EPSD	COSMIC	2.968	Down-regulation
CMGC_CDKL_CDKL5_ST	Q9UPN4	CEP131	O76039	CDKL5	S30	S30Y	30	Missense	central	0	yes	3.354	0.000	EPSD	COSMIC	2.968	Loss
CMGC_CDKL_CDKL5_ST	Q9UPN4	CEP131	O76039	CDKL5	S30	A37T	37	Missense	distal	7	no	3.354	3.327	EPSD	COSMIC	2.968	Down-regulation
CMGC_CDKL_CDKL5_ST	Q9UPN4	CEP131	O76039	CDKL5	S35	R32H	32	Missense	distal	-3	no	3.858	3.175	PhosphoSitePlus	COSMIC	2.968	Down-regulation
CMGC_CDKL_CDKL5_ST	Q9UPN4	CEP131	O76039	CDKL5	S35	S30Y	30	Missense	distal	-5	no	3.858	4.349	PhosphoSitePlus	COSMIC	2.968	Up-regulation
CMGC_CDKL_CDKL5_ST	Q9UPN4	CEP131	O76039	CDKL5	S35	A37T	37	Missense	proximal	2	no	3.858	3.964	PhosphoSitePlus	COSMIC	2.968	Up-regulation
CMGC_CDKL_CDKL5_ST	Q9UPN4	CEP131	O76039	CDKL5	T38	R31W	31	Missense	distal	-7	no	3.304	3.593	EPSD	COSMIC	2.968	Up-regulation
CMGC_CDKL_CDKL5_ST	Q9UPN4	CEP131	O76039	CDKL5	T38	R32H	32	Missense	distal	-6	no	3.304	3.515	EPSD	COSMIC	2.968	Up-regulation
CMGC_CDKL_CDKL5_ST	Q9UPN4	CEP131	O76039	CDKL5	T38	V43I	43	Missense	distal	5	no	3.304	3.308	EPSD	COSMIC	2.968	Up-regulation
CMGC_CDKL_CDKL5_ST	Q9UPN4	CEP131	O76039	CDKL5	T38	A37T	37	Missense	proximal	-1	no	3.304	3.380	EPSD	COSMIC	2.968	Up-regulation
CMGC_CDKL_CDKL5_ST	Q9UPN4	CEP131	O76039	CDKL5	T39	R32H	32	Missense	distal	-7	no	3.966	4.902	EPSD	COSMIC	2.968	Up-regulation
CMGC_CDKL_CDKL5_ST	Q9UPN4	CEP131	O76039	CDKL5	T39	V43I	43	Missense	distal	4	no	3.966	3.954	EPSD	COSMIC	2.968	Down-regulation
CMGC_CDKL_CDKL5_ST	Q9UPN4	CEP131	O76039	CDKL5	T39	A37T	37	Missense	proximal	-2	no	3.966	3.983	EPSD	COSMIC	2.968	Up-regulation
CMGC_CDKL_CDKL5_ST	Q9UPN4	CEP131	O76039	CDKL5	S208	N210S	210	Missense	proximal	2	no	2.820	2.996	EPSD	COSMIC	2.968	Gain
CMGC_CDKL_CDKL5_ST	Q9UPN4	CEP131	O76039	CDKL5	T248	R241L	241	Missense	distal	-7	no	3.437	2.680	EPSD	COSMIC	2.968	Loss
CMGC_CDKL_CDKL5_ST	Q9UPN4	CEP131	O76039	CDKL5	T248	G249D	249	Missense	proximal	1	no	3.437	3.441	EPSD	COSMIC	2.968	Up-regulation
CMGC_CDKL_CDKL5_ST	Q9UPN4	CEP131	O76039	CDKL5	T248	R253W	253	Missense	distal	5	no	3.437	3.441	EPSD	COSMIC	2.968	Up-regulation
CMGC_CDKL_CDKL5_ST	Q9UPN4	CEP131	O76039	CDKL5	T248	R253L	253	Missense	distal	5	no	3.437	3.438	EPSD	COSMIC	2.968	Up-regulation
CMGC_CDKL_CDKL5_ST	Q9UPN4	CEP131	O76039	CDKL5	T248	R253Q	253	Missense	distal	5	no	3.437	3.440	EPSD	COSMIC	2.968	Up-regulation
CMGC_CDKL_CDKL5_ST	Q9UPN4	CEP131	O76039	CDKL5	T248	R241Q	241	Missense	distal	-7	no	3.437	3.611	EPSD	COSMIC	2.968	Up-regulation
CMGC_CDKL_CDKL5_ST	Q9UPN4	CEP131	O76039	CDKL5	T248	G245E	245	Missense	distal	-3	no	3.437	3.677	EPSD	COSMIC	2.968	Up-regulation
CMGC_CDKL_CDKL5_ST	Q9UPN4	CEP131	O76039	CDKL5	S453	P446Q	446	Missense	distal	-7	no	3.839	2.600	EPSD	COSMIC	2.968	Loss
CMGC_CDKL_CDKL5_ST	Q9UPN4	CEP131	O76039	CDKL5	S453	G455V	455	Missense	proximal	2	no	3.839	3.924	EPSD	COSMIC	2.968	Up-regulation
CMGC_CDKL_CDKL5_ST	Q9UPN4	CEP131	O76039	CDKL5	S534	Q530L	530	Missense	distal	-4	no	3.327	3.333	EPSD	COSMIC	2.968	Up-regulation
CMGC_CDKL_CDKL5_ST	Q9UPN4	CEP131	O76039	CDKL5	S549	G543V	543	Missense	distal	-6	no	3.467	3.466	EPSD	COSMIC	2.968	Down-regulation
CMGC_CDKL_CDKL5_ST	O76039	CDKL5	O76039	CDKL5	T169	N165H	165	Missense	distal	-4	no	12.683	12.679	EPSD;PhosphoSitePlus	COSMIC	2.968	Down-regulation
CMGC_CDKL_CDKL5_ST	O76039	CDKL5	O76039	CDKL5	S306	T299P	299	Missense	distal	-7	no	2.128	3.272	EPSD	COSMIC	2.968	Gain
CMGC_CDKL_CDKL5_ST	O76039	CDKL5	O76039	CDKL5	S343	L349R	349	Missense	distal	6	no	2.741	3.304	EPSD	COSMIC	2.968	Gain
CMGC_CDKL_CDKL5_ST	O76039	CDKL5	O76039	CDKL5	S350	P354L	354	Missense	distal	4	no	4.962	5.000	EPSD	COSMIC	2.968	Up-regulation
CMGC_CDKL_CDKL5_ST	O76039	CDKL5	O76039	CDKL5	S350	L349R	349	Missense	proximal	-1	no	4.962	4.929	EPSD	COSMIC	2.968	Down-regulation
CMGC_CDKL_CDKL5_ST	O76039	CDKL5	O76039	CDKL5	S375	N368H	368	Missense	distal	-7	no	2.764	4.326	EPSD	COSMIC	2.968	Gain
CMGC_CDKL_CDKL5_ST	O76039	CDKL5	O76039	CDKL5	T484	S479R	479	Missense	distal	-5	no	2.464	3.058	EPSD	COSMIC	2.968	Gain
CMGC_CDKL_CDKL5_ST	O76039	CDKL5	O76039	CDKL5	S526	S526Y	526	Missense	central	0	yes	2.979	0.000	EPSD	COSMIC	2.968	Loss
CMGC_CDKL_CDKL5_ST	O76039	CDKL5	O76039	CDKL5	S526	P530L	530	Missense	distal	4	no	2.979	3.018	EPSD	COSMIC	2.968	Up-regulation
CMGC_CDKL_CDKL5_ST	O76039	CDKL5	O76039	CDKL5	S526	T528P	528	Missense	proximal	2	no	2.979	3.015	EPSD	COSMIC	2.968	Up-regulation
CMGC_CDKL_CDKL5_ST	O76039	CDKL5	O76039	CDKL5	S526	P532L	532	Missense	distal	6	no	2.979	2.918	EPSD	COSMIC	2.968	Loss
CMGC_CDKL_CDKL5_ST	O76039	CDKL5	O76039	CDKL5	S565	R558H	558	Missense	distal	-7	no	2.434	3.369	EPSD	COSMIC	2.968	Gain
CMGC_CDKL_CDKL5_ST	O76039	CDKL5	O76039	CDKL5	T658	P655S	655	Missense	distal	-3	no	2.677	3.057	EPSD	COSMIC	2.968	Gain
CMGC_CDKL_CDKL5_ST	O76039	CDKL5	O76039	CDKL5	S766	E763G	763	Missense	distal	-3	no	4.173	3.934	EPSD	COSMIC	2.968	Down-regulation
CMGC_CDKL_CDKL5_ST	O76039	CDKL5	O76039	CDKL5	S766	S766G	766	Missense	central	0	yes	4.173	0.000	EPSD	COSMIC	2.968	Loss
CMGC_CDKL_CDKL5_ST	O76039	CDKL5	O76039	CDKL5	S768	E763G	763	Missense	distal	-5	no	2.983	2.831	EPSD	COSMIC	2.968	Loss
CMGC_CDKL_CDKL5_ST	O76039	CDKL5	O76039	CDKL5	S768	S766G	766	Missense	proximal	-2	no	2.983	3.330	EPSD	COSMIC	2.968	Up-regulation
CMGC_CDKL_CDKL5_ST	O76039	CDKL5	O76039	CDKL5	T792	K787N	787	Missense	distal	-5	no	2.440	3.122	EPSD	COSMIC	2.968	Gain
CMGC_CDKL_CDKL5_ST	O76039	CDKL5	O76039	CDKL5	S796	P799S	799	Missense	distal	3	no	3.186	2.536	EPSD	COSMIC	2.968	Loss
CMGC_CDKL_CDKL5_ST	O76039	CDKL5	O76039	CDKL5	S796	P794S	794	Missense	proximal	-2	no	3.186	2.708	EPSD	COSMIC	2.968	Loss
CMGC_CDKL_CDKL5_ST	O76039	CDKL5	O76039	CDKL5	T803	Q805H	805	Missense	proximal	2	no	2.974	2.912	EPSD	COSMIC	2.968	Loss
CMGC_CDKL_CDKL5_ST	O76039	CDKL5	O76039	CDKL5	T803	P799S	799	Missense	distal	-4	no	2.974	3.038	EPSD	COSMIC	2.968	Up-regulation
CMGC_CDKL_CDKL5_ST	Q66K74	MAP1S	O76039	CDKL5	S321	G320C	320	Missense	proximal	-1	no	4.124	4.136	EPSD	COSMIC	2.968	Up-regulation
CMGC_CDKL_CDKL5_ST	Q66K74	MAP1S	O76039	CDKL5	S321	A317V	317	Missense	distal	-4	no	4.124	4.113	EPSD	COSMIC	2.968	Down-regulation
CMGC_CDKL_CDKL5_ST	Q66K74	MAP1S	O76039	CDKL5	S321	R327C	327	Missense	distal	6	no	4.124	3.720	EPSD	COSMIC	2.968	Down-regulation
CMGC_CDKL_CDKL5_ST	Q66K74	MAP1S	O76039	CDKL5	S481	E474D	474	Missense	distal	-7	no	5.895	5.713	EPSD	COSMIC	2.968	Down-regulation
CMGC_CDKL_CDKL5_ST	Q66K74	MAP1S	O76039	CDKL5	S646	A648T	648	Missense	proximal	2	no	3.021	3.127	EPSD	COSMIC	2.968	Up-regulation
CMGC_CDKL_CDKL5_ST	Q66K74	MAP1S	O76039	CDKL5	S646	S651I	651	Missense	distal	5	no	3.021	3.024	EPSD	COSMIC	2.968	Up-regulation
CMGC_CDKL_CDKL5_ST	Q66K74	MAP1S	O76039	CDKL5	S651	A648T	648	Missense	distal	-3	no	3.564	2.957	EPSD	COSMIC	2.968	Loss
CMGC_CDKL_CDKL5_ST	Q66K74	MAP1S	O76039	CDKL5	S651	S651I	651	Missense	central	0	yes	3.564	0.000	EPSD	COSMIC	2.968	Loss
CMGC_CDKL_CDKL5_ST	Q66K74	MAP1S	O76039	CDKL5	S651	S657I	657	Missense	distal	6	no	3.564	3.222	EPSD	COSMIC	2.968	Down-regulation
CMGC_CDKL_CDKL5_ST	Q66K74	MAP1S	O76039	CDKL5	S657	G661A	661	Missense	distal	4	no	4.367	4.422	EPSD	COSMIC	2.968	Up-regulation
CMGC_CDKL_CDKL5_ST	Q66K74	MAP1S	O76039	CDKL5	S657	S651I	651	Missense	distal	-6	no	4.367	4.369	EPSD	COSMIC	2.968	Up-regulation
CMGC_CDKL_CDKL5_ST	Q66K74	MAP1S	O76039	CDKL5	S657	S657I	657	Missense	central	0	yes	4.367	0.000	EPSD	COSMIC	2.968	Loss
CMGC_CDKL_CDKL5_ST	Q66K74	MAP1S	O76039	CDKL5	S766	E772K	772	Missense	distal	6	no	5.382	5.387	EPSD	COSMIC	2.968	Up-regulation
CMGC_CDKL_CDKL5_ST	Q66K74	MAP1S	O76039	CDKL5	S788	S795P	795	Missense	distal	7	no	3.706	3.724	EPSD	COSMIC	2.968	Up-regulation
CMGC_CDKL_CDKL5_ST	Q66K74	MAP1S	O76039	CDKL5	T941	G937R	937	Missense	distal	-4	no	3.367	3.373	EPSD	COSMIC	2.968	Up-regulation
CMGC_CDKL_CDKL5_ST	Q8TDM6	DLG5	O76039	CDKL5	S204	M199L	199	Missense	distal	-5	no	2.825	3.015	EPSD	COSMIC	2.968	Gain
CMGC_CDKL_CDKL5_ST	Q8TDM6	DLG5	O76039	CDKL5	S711	V717I	717	Missense	distal	6	no	3.698	3.685	EPSD	COSMIC	2.968	Down-regulation
CMGC_CDKL_CDKL5_ST	Q8TDM6	DLG5	O76039	CDKL5	S711	K710T	710	Missense	proximal	-1	no	3.698	3.751	EPSD	COSMIC	2.968	Up-regulation
CMGC_CDKL_CDKL5_ST	Q8TDM6	DLG5	O76039	CDKL5	T849	E853Q	853	Missense	distal	4	no	4.364	4.322	EPSD	COSMIC	2.968	Down-regulation
CMGC_CDKL_CDKL5_ST	Q8TDM6	DLG5	O76039	CDKL5	T849	R855T	855	Missense	distal	6	no	4.364	4.053	EPSD	COSMIC	2.968	Down-regulation
CMGC_CDKL_CDKL5_ST	Q8TDM6	DLG5	O76039	CDKL5	T849	Y848C	848	Missense	proximal	-1	no	4.364	4.362	EPSD	COSMIC	2.968	Down-regulation
CMGC_CDKL_CDKL5_ST	Q8TDM6	DLG5	O76039	CDKL5	T849	D850E	850	Missense	proximal	1	no	4.364	4.391	EPSD	COSMIC	2.968	Up-regulation
CMGC_CDKL_CDKL5_ST	Q8TDM6	DLG5	O76039	CDKL5	S865	S866F	866	Missense	proximal	1	no	4.577	4.530	EPSD	COSMIC	2.968	Down-regulation
CMGC_CDKL_CDKL5_ST	Q8TDM6	DLG5	O76039	CDKL5	S897	R903C	903	Missense	distal	6	no	3.860	3.455	EPSD	COSMIC	2.968	Down-regulation
CMGC_CDKL_CDKL5_ST	Q8TDM6	DLG5	O76039	CDKL5	S897	R890H	890	Missense	distal	-7	no	3.860	4.795	EPSD	COSMIC;GDSC	2.968	Up-regulation
CMGC_CDKL_CDKL5_ST	Q8TDM6	DLG5	O76039	CDKL5	S900	R903C	903	Missense	distal	3	no	3.768	3.759	EPSD	COSMIC	2.968	Down-regulation
CMGC_CDKL_CDKL5_ST	Q8TDM6	DLG5	O76039	CDKL5	S1019	P1016L	1016	Missense	distal	-3	no	3.783	4.078	EPSD	COSMIC	2.968	Up-regulation
CMGC_CDKL_CDKL5_ST	Q8TDM6	DLG5	O76039	CDKL5	S1019	D1020N	1020	Missense	proximal	1	no	3.783	3.735	EPSD	COSMIC;GDSC	2.968	Down-regulation
CMGC_CDKL_CDKL5_ST	Q8TDM6	DLG5	O76039	CDKL5	S1076	S1075F	1075	Missense	proximal	-1	no	4.284	4.350	EPSD	COSMIC;CCLE	2.968	Up-regulation
CMGC_CDKL_CDKL5_ST	Q8TDM6	DLG5	O76039	CDKL5	S1118	R1111C	1111	Missense	distal	-7	no	4.571	4.851	EPSD	COSMIC	2.968	Up-regulation
CMGC_CDKL_CDKL5_ST	Q8TDM6	DLG5	O76039	CDKL5	S1265	S1258N	1258	Missense	distal	-7	no	4.843	3.690	EPSD	COSMIC	2.968	Down-regulation
CMGC_CDKL_CDKL5_ST	Q8TDM6	DLG5	O76039	CDKL5	S1265	S1264L	1264	Missense	proximal	-1	no	4.843	4.925	EPSD	COSMIC	2.968	Up-regulation
CMGC_CDKL_CDKL5_ST	Q8TDM6	DLG5	O76039	CDKL5	S1265	S1265N	1265	Missense	central	0	yes	4.843	0.000	EPSD	COSMIC	2.968	Loss
CMGC_CDKL_CDKL5_ST	Q8TDM6	DLG5	O76039	CDKL5	S1278	R1284Q	1284	Missense	distal	6	no	4.516	4.137	EPSD	COSMIC	2.968	Down-regulation
CMGC_CDKL_CDKL5_ST	Q8TDM6	DLG5	O76039	CDKL5	S1278	P1280S	1280	Missense	proximal	2	no	4.516	4.305	EPSD	COSMIC;CCLE	2.968	Down-regulation
CMGC_CDKL_CDKL5_ST	Q8TDM6	DLG5	O76039	CDKL5	S1278	R1273C	1273	Missense	distal	-5	no	4.516	4.287	EPSD	COSMIC	2.968	Down-regulation
CMGC_CDKL_CDKL5_ST	Q8TDM6	DLG5	O76039	CDKL5	T1677	T1677A	1677	Missense	central	0	yes	3.207	0.000	EPSD	COSMIC	2.968	Loss
CMGC_CDKL_CDKL5_ST	Q8TDM6	DLG5	O76039	CDKL5	T1677	D1673E	1673	Missense	distal	-4	no	3.207	3.210	EPSD	COSMIC	2.968	Up-regulation
CMGC_CDKL_CDKL5_ST	Q8TDM6	DLG5	O76039	CDKL5	T1677	T1679R	1679	Missense	proximal	2	no	3.207	3.153	EPSD	COSMIC	2.968	Down-regulation
CMGC_CDKL_CDKL5_ST	Q8TDM6	DLG5	O76039	CDKL5	T1677	A1676S	1676	Missense	proximal	-1	no	3.207	3.197	EPSD	COSMIC	2.968	Down-regulation
CMGC_CDKL_CDKL5_ST	Q8TDM6	DLG5	O76039	CDKL5	S1700	H1695Q	1695	Missense	distal	-5	no	4.675	5.055	EPSD	COSMIC	2.968	Up-regulation
CMGC_MAPK_p38_MAPK11_ST	P15336	ATF2	Q15759	MAPK11	T69	T73A	73	Missense	distal	4	no	47.733	47.701	PhosphoSitePlus;EPSD	COSMIC	33.886	Down-regulation
CMGC_MAPK_p38_MAPK11_ST	P15336	ATF2	Q15759	MAPK11	T69	F75L	75	Missense	distal	6	no	47.733	47.703	PhosphoSitePlus;EPSD	COSMIC	33.886	Down-regulation
CMGC_MAPK_p38_MAPK11_ST	P15336	ATF2	Q15759	MAPK11	T69	R74T	74	Missense	distal	5	no	47.733	47.756	PhosphoSitePlus;EPSD	COSMIC	33.886	Up-regulation
CMGC_MAPK_p38_MAPK11_ST	P15336	ATF2	Q15759	MAPK11	T69	I64V	64	Missense	distal	-5	no	47.733	47.730	PhosphoSitePlus;EPSD	COSMIC	33.886	Down-regulation
CMGC_MAPK_p38_MAPK11_ST	P15336	ATF2	Q15759	MAPK11	T69	D67E	67	Missense	proximal	-2	no	47.733	47.784	PhosphoSitePlus;EPSD	COSMIC	33.886	Up-regulation
CMGC_MAPK_p38_MAPK11_ST	P15336	ATF2	Q15759	MAPK11	T71	T73A	73	Missense	proximal	2	no	48.904	46.323	EPSD;PhosphoSitePlus	COSMIC	33.886	Down-regulation
CMGC_MAPK_p38_MAPK11_ST	P15336	ATF2	Q15759	MAPK11	T71	F75L	75	Missense	distal	4	no	48.904	48.595	EPSD;PhosphoSitePlus	COSMIC	33.886	Down-regulation
CMGC_MAPK_p38_MAPK11_ST	P15336	ATF2	Q15759	MAPK11	T71	R74T	74	Missense	distal	3	no	48.904	49.466	EPSD;PhosphoSitePlus	COSMIC	33.886	Up-regulation
CMGC_MAPK_p38_MAPK11_ST	P15336	ATF2	Q15759	MAPK11	T71	I64V	64	Missense	distal	-7	no	48.904	48.971	EPSD;PhosphoSitePlus	COSMIC	33.886	Up-regulation
CMGC_MAPK_p38_MAPK11_ST	P15336	ATF2	Q15759	MAPK11	T71	D67E	67	Missense	distal	-4	no	48.904	48.191	EPSD;PhosphoSitePlus	COSMIC	33.886	Down-regulation
CMGC_MAPK_p38_MAPK11_ST	P15336	ATF2	Q15759	MAPK11	S90	P91S	91	Missense	proximal	1	no	41.360	25.861	EPSD	COSMIC	33.886	Loss
CMGC_MAPK_p38_MAPK11_ST	P15336	ATF2	Q15759	MAPK11	S90	A89V	89	Missense	proximal	-1	no	41.360	40.617	EPSD	COSMIC	33.886	Down-regulation
CMGC_MAPK_p38_MAPK11_ST	P15336	ATF2	Q15759	MAPK11	S90	P91L	91	Missense	proximal	1	no	41.360	31.542	EPSD	COSMIC	33.886	Loss
CMGC_MAPK_p38_MAPK11_ST	P15336	ATF2	Q15759	MAPK11	S90	G83C	83	Missense	distal	-7	no	41.360	41.210	EPSD	COSMIC	33.886	Down-regulation
CMGC_MAPK_p38_MAPK11_ST	P15336	ATF2	Q15759	MAPK11	S112	M107I	107	Missense	distal	-5	no	44.471	44.262	EPSD	COSMIC;GDSC;CCLE	33.886	Down-regulation
CMGC_MAPK_p38_MAPK11_ST	P15336	ATF2	Q15759	MAPK11	S112	K105T	105	Missense	distal	-7	no	44.471	44.467	EPSD	COSMIC;GDSC;CCLE	33.886	Down-regulation
CMGC_MAPK_p38_MAPK11_ST	P15336	ATF2	Q15759	MAPK11	S112	K106R	106	Missense	distal	-6	no	44.471	44.428	EPSD	COSMIC	33.886	Down-regulation
CMGC_MAPK_p38_MAPK11_ST	P15336	ATF2	Q15759	MAPK11	S112	D110E	110	Missense	proximal	-2	no	44.471	44.523	EPSD	COSMIC	33.886	Up-regulation
CMGC_MAPK_p38_MAPK11_ST	P15336	ATF2	Q15759	MAPK11	T116	D110E	110	Missense	distal	-6	no	41.067	41.137	EPSD	COSMIC	33.886	Up-regulation
CMGC_MAPK_p38_MAPK11_ST	P15336	ATF2	Q15759	MAPK11	S136	P141T	141	Missense	distal	5	no	36.910	36.938	EPSD	COSMIC	33.886	Up-regulation
CMGC_MAPK_p38_MAPK11_ST	P15336	ATF2	Q15759	MAPK11	S136	P141L	141	Missense	distal	5	no	36.910	36.813	EPSD	COSMIC	33.886	Down-regulation
CMGC_MAPK_p38_MAPK11_ST	P15336	ATF2	Q15759	MAPK11	S136	P137S	137	Missense	proximal	1	no	36.910	21.411	EPSD	COSMIC	33.886	Loss
CMGC_MAPK_p38_MAPK11_ST	P15336	ATF2	Q15759	MAPK11	S265	S266P	266	Missense	proximal	1	no	22.073	37.572	EPSD	COSMIC	33.886	Gain
CMGC_MAPK_p38_MAPK11_ST	P15336	ATF2	Q15759	MAPK11	S314	R311Q	311	Missense	distal	-3	no	35.026	34.852	EPSD	COSMIC;GDSC;CCLE	33.886	Down-regulation
CMGC_MAPK_p38_MAPK11_ST	P15336	ATF2	Q15759	MAPK11	S314	Q316K	316	Missense	proximal	2	no	35.026	35.461	EPSD	COSMIC	33.886	Up-regulation
CMGC_MAPK_p38_MAPK11_ST	P15336	ATF2	Q15759	MAPK11	S314	Q317H	317	Missense	distal	3	no	35.026	35.038	EPSD	COSMIC	33.886	Up-regulation
CMGC_MAPK_p38_MAPK11_ST	P15336	ATF2	Q15759	MAPK11	T320	Q316K	316	Missense	distal	-4	no	32.684	35.093	EPSD	COSMIC	33.886	Gain
CMGC_MAPK_p38_MAPK11_ST	P15336	ATF2	Q15759	MAPK11	T325	P326L	326	Missense	proximal	1	no	40.490	30.673	EPSD	COSMIC;GDSC	33.886	Loss
CMGC_MAPK_p38_MAPK11_ST	P15336	ATF2	Q15759	MAPK11	T325	P326T	326	Missense	proximal	1	no	40.490	15.906	EPSD	COSMIC	33.886	Loss
CMGC_MAPK_p38_MAPK11_ST	P15336	ATF2	Q15759	MAPK11	T325	H331Y	331	Missense	distal	6	no	40.490	40.457	EPSD	COSMIC	33.886	Down-regulation
CMGC_MAPK_p38_MAPK11_ST	P15336	ATF2	Q15759	MAPK11	S328	P326L	326	Missense	proximal	-2	no	36.572	36.235	EPSD	COSMIC;GDSC	33.886	Down-regulation
CMGC_MAPK_p38_MAPK11_ST	P15336	ATF2	Q15759	MAPK11	S328	P326T	326	Missense	proximal	-2	no	36.572	36.706	EPSD	COSMIC	33.886	Up-regulation
CMGC_MAPK_p38_MAPK11_ST	P15336	ATF2	Q15759	MAPK11	S328	Q335H	335	Missense	distal	7	no	36.572	36.687	EPSD	COSMIC	33.886	Up-regulation
CMGC_MAPK_p38_MAPK11_ST	P15336	ATF2	Q15759	MAPK11	S328	P334S	334	Missense	distal	6	no	36.572	36.564	EPSD	COSMIC	33.886	Down-regulation
CMGC_MAPK_p38_MAPK11_ST	P15336	ATF2	Q15759	MAPK11	S328	H331Y	331	Missense	distal	3	no	36.572	36.791	EPSD	COSMIC	33.886	Up-regulation
CMGC_MAPK_p38_MAPK11_ST	P15336	ATF2	Q15759	MAPK11	T333	Q337K	337	Missense	distal	4	no	42.604	43.507	EPSD	COSMIC	33.886	Up-regulation
CMGC_MAPK_p38_MAPK11_ST	P15336	ATF2	Q15759	MAPK11	T333	P326L	326	Missense	distal	-7	no	42.604	42.518	EPSD	COSMIC;GDSC	33.886	Down-regulation
CMGC_MAPK_p38_MAPK11_ST	P15336	ATF2	Q15759	MAPK11	T333	P326T	326	Missense	distal	-7	no	42.604	42.721	EPSD	COSMIC	33.886	Up-regulation
CMGC_MAPK_p38_MAPK11_ST	P15336	ATF2	Q15759	MAPK11	T333	Q335H	335	Missense	proximal	2	no	42.604	41.509	EPSD	COSMIC	33.886	Down-regulation
CMGC_MAPK_p38_MAPK11_ST	P15336	ATF2	Q15759	MAPK11	T333	P334S	334	Missense	proximal	1	no	42.604	27.105	EPSD	COSMIC	33.886	Loss
CMGC_MAPK_p38_MAPK11_ST	P15336	ATF2	Q15759	MAPK11	T333	H331Y	331	Missense	proximal	-2	no	42.604	43.034	EPSD	COSMIC	33.886	Up-regulation
CMGC_MAPK_p38_MAPK11_ST	P15336	ATF2	Q15759	MAPK11	S446	S442L	442	Missense	distal	-4	no	43.614	40.326	EPSD	COSMIC	33.886	Down-regulation
CMGC_MAPK_p38_MAPK11_ST	P15336	ATF2	Q15759	MAPK11	S446	P444L	444	Missense	proximal	-2	no	43.614	43.278	EPSD	COSMIC	33.886	Down-regulation
CMGC_MAPK_p38_MAPK11_ST	P15336	ATF2	Q15759	MAPK11	S446	P444T	444	Missense	proximal	-2	no	43.614	43.749	EPSD	COSMIC	33.886	Up-regulation
CMGC_MAPK_p38_MAPK11_ST	P15336	ATF2	Q15759	MAPK11	S446	S442P	442	Missense	distal	-4	no	43.614	41.897	EPSD	COSMIC	33.886	Down-regulation
CMGC_MAPK_p38_MAPK11_ST	P15336	ATF2	Q15759	MAPK11	S446	P444Q	444	Missense	proximal	-2	no	43.614	42.884	EPSD	COSMIC	33.886	Down-regulation
CMGC_MAPK_p38_MAPK11_ST	P04179	SOD2	Q15759	MAPK11	S106	L105R	105	Missense	proximal	-1	no	47.202	47.480	EPSD;PhosphoSitePlus	COSMIC	33.886	Up-regulation
CMGC_MAPK_p38_MAPK11_ST	P04179	SOD2	Q15759	MAPK11	S106	G109C	109	Missense	distal	3	no	47.202	45.365	EPSD;PhosphoSitePlus	COSMIC	33.886	Down-regulation
CMGC_MAPK_p38_MAPK11_ST	Q15759	MAPK11	Q15759	MAPK11	S61	S56L	56	Missense	distal	-5	no	35.667	35.369	EPSD	COSMIC	33.886	Down-regulation
CMGC_MAPK_p38_MAPK11_ST	Q15759	MAPK11	Q15759	MAPK11	S243	I250F	250	Missense	distal	7	no	35.783	36.077	EPSD	COSMIC	33.886	Up-regulation
CMGC_MAPK_p38_MAPK11_ST	Q15759	MAPK11	Q15759	MAPK11	S261	M265I	265	Missense	distal	4	no	43.429	41.356	EPSD;PhosphoSitePlus	COSMIC;GDSC;CCLE	33.886	Down-regulation
CMGC_MAPK_p38_MAPK11_ST	O00418	EEF2K	Q15759	MAPK11	S359	T364N	364	Missense	distal	5	no	45.186	45.384	EPSD	COSMIC	33.886	Up-regulation
CMGC_MAPK_p38_MAPK11_ST	O00418	EEF2K	Q15759	MAPK11	S359	E355K	355	Missense	distal	-4	no	45.186	47.012	EPSD	COSMIC	33.886	Up-regulation
CMGC_MAPK_p38_MAPK11_ST	O00418	EEF2K	Q15759	MAPK11	S396	S398C	398	Missense	proximal	2	no	51.873	49.879	PhosphoSitePlus	COSMIC	33.886	Down-regulation
CMGC_MAPK_p38_MAPK11_ST	O00418	EEF2K	Q15759	MAPK11	S396	T389I	389	Missense	distal	-7	no	51.873	51.600	PhosphoSitePlus	COSMIC	33.886	Down-regulation
CMGC_MAPK_p38_MAPK11_ST	O00418	EEF2K	Q15759	MAPK11	S396	S399L	399	Missense	distal	3	no	51.873	50.452	PhosphoSitePlus	COSMIC	33.886	Down-regulation
CMGC_MAPK_p38_MAPK11_ST	O00418	EEF2K	Q15759	MAPK11	S396	P394L	394	Missense	proximal	-2	no	51.873	51.537	PhosphoSitePlus	COSMIC;GDSC;CCLE	33.886	Down-regulation
CMGC_MAPK_p38_MAPK11_ST	O00418	EEF2K	Q15759	MAPK11	S396	P394S	394	Missense	proximal	-2	no	51.873	51.812	PhosphoSitePlus	COSMIC	33.886	Down-regulation
CMGC_MAPK_p38_MAPK11_ST	O00418	EEF2K	Q15759	MAPK11	S398	S399L	399	Missense	proximal	1	no	29.409	35.090	EPSD	COSMIC	33.886	Gain
CMGC_MAPK_p38_MAPK11_ST	O00418	EEF2K	Q15759	MAPK11	T401	S398C	398	Missense	distal	-3	no	39.858	40.877	EPSD	COSMIC	33.886	Up-regulation
CMGC_MAPK_p38_MAPK11_ST	O00418	EEF2K	Q15759	MAPK11	T401	S399L	399	Missense	proximal	-2	no	39.858	39.583	EPSD	COSMIC	33.886	Down-regulation
CMGC_MAPK_p38_MAPK11_ST	O00418	EEF2K	Q15759	MAPK11	T401	P394L	394	Missense	distal	-7	no	39.858	39.773	EPSD	COSMIC;GDSC;CCLE	33.886	Down-regulation
CMGC_MAPK_p38_MAPK11_ST	O00418	EEF2K	Q15759	MAPK11	T401	P394S	394	Missense	distal	-7	no	39.858	39.997	EPSD	COSMIC	33.886	Up-regulation
CMGC_MAPK_p38_MAPK11_ST	Q00613	HSF1	Q15759	MAPK11	S230	R227Q	227	Missense	distal	-3	no	39.225	39.051	EPSD	COSMIC;GDSC	33.886	Down-regulation
CMGC_MAPK_p38_MAPK11_ST	Q00613	HSF1	Q15759	MAPK11	S230	G236S	236	Missense	distal	6	no	39.225	39.191	EPSD	COSMIC;CCLE	33.886	Down-regulation
CMGC_MAPK_p38_MAPK11_ST	Q00613	HSF1	Q15759	MAPK11	S230	S237L	237	Missense	distal	7	no	39.225	38.403	EPSD	COSMIC	33.886	Down-regulation
CMGC_MAPK_p38_MAPK11_ST	Q00613	HSF1	Q15759	MAPK11	S241	G236S	236	Missense	distal	-5	no	37.122	37.283	EPSD	COSMIC;CCLE	33.886	Up-regulation
CMGC_MAPK_p38_MAPK11_ST	Q00613	HSF1	Q15759	MAPK11	S241	S237L	237	Missense	distal	-4	no	37.122	33.834	EPSD	COSMIC	33.886	Loss
CMGC_MAPK_p38_MAPK11_ST	Q00613	HSF1	Q15759	MAPK11	S241	P239H	239	Missense	proximal	-2	no	37.122	36.520	EPSD	COSMIC	33.886	Down-regulation
CMGC_MAPK_p38_MAPK11_ST	Q00613	HSF1	Q15759	MAPK11	S241	S244F	244	Missense	distal	3	no	37.122	35.952	EPSD	COSMIC	33.886	Down-regulation
CMGC_MAPK_p38_MAPK11_ST	Q00613	HSF1	Q15759	MAPK11	S275	S279F	279	Missense	distal	4	no	42.662	41.345	EPSD	COSMIC	33.886	Down-regulation
CMGC_MAPK_p38_MAPK11_ST	Q00613	HSF1	Q15759	MAPK11	S275	P280L	280	Missense	distal	5	no	42.662	42.565	EPSD	COSMIC	33.886	Down-regulation
CMGC_MAPK_p38_MAPK11_ST	Q00613	HSF1	Q15759	MAPK11	S275	I268V	268	Missense	distal	-7	no	42.662	42.729	EPSD	COSMIC	33.886	Up-regulation
CMGC_MAPK_p38_MAPK11_ST	Q00613	HSF1	Q15759	MAPK11	S275	G281S	281	Missense	distal	6	no	42.662	42.629	EPSD	COSMIC	33.886	Down-regulation
CMGC_MAPK_p38_MAPK11_ST	Q00613	HSF1	Q15759	MAPK11	S279	S279F	279	Missense	central	0	yes	40.834	0.000	EPSD	COSMIC	33.886	Loss
CMGC_MAPK_p38_MAPK11_ST	Q00613	HSF1	Q15759	MAPK11	S279	P280L	280	Missense	proximal	1	no	40.834	31.016	EPSD	COSMIC	33.886	Loss
CMGC_MAPK_p38_MAPK11_ST	Q00613	HSF1	Q15759	MAPK11	S279	G281S	281	Missense	proximal	2	no	40.834	42.873	EPSD	COSMIC	33.886	Up-regulation
CMGC_MAPK_p38_MAPK11_ST	Q00613	HSF1	Q15759	MAPK11	S279	S283N	283	Missense	distal	4	no	40.834	39.552	EPSD	COSMIC	33.886	Down-regulation
CMGC_MAPK_p38_MAPK11_ST	Q00613	HSF1	Q15759	MAPK11	S292	R287K	287	Missense	distal	-5	no	44.972	45.142	EPSD	COSMIC	33.886	Up-regulation
CMGC_MAPK_p38_MAPK11_ST	Q00613	HSF1	Q15759	MAPK11	S303	S303G	303	Missense	central	0	yes	47.052	0.000	EPSD;PhosphoSitePlus	COSMIC	33.886	Loss
CMGC_MAPK_p38_MAPK11_ST	Q00613	HSF1	Q15759	MAPK11	S303	P304L	304	Missense	proximal	1	no	47.052	37.235	EPSD;PhosphoSitePlus	COSMIC;GDSC	33.886	Down-regulation
CMGC_MAPK_p38_MAPK11_ST	Q00613	HSF1	Q15759	MAPK11	S303	R309G	309	Missense	distal	6	no	47.052	47.040	EPSD;PhosphoSitePlus	COSMIC	33.886	Down-regulation
CMGC_MAPK_p38_MAPK11_ST	Q00613	HSF1	Q15759	MAPK11	S307	S303G	303	Missense	distal	-4	no	47.026	45.021	PhosphoSitePlus;EPSD	COSMIC	33.886	Down-regulation
CMGC_MAPK_p38_MAPK11_ST	Q00613	HSF1	Q15759	MAPK11	S307	P304L	304	Missense	distal	-3	no	47.026	47.443	PhosphoSitePlus;EPSD	COSMIC;GDSC	33.886	Up-regulation
CMGC_MAPK_p38_MAPK11_ST	Q00613	HSF1	Q15759	MAPK11	S307	R309G	309	Missense	proximal	2	no	47.026	45.732	PhosphoSitePlus;EPSD	COSMIC	33.886	Down-regulation
CMGC_MAPK_p38_MAPK11_ST	Q00613	HSF1	Q15759	MAPK11	S314	R309G	309	Missense	distal	-5	no	37.205	37.256	EPSD	COSMIC	33.886	Up-regulation
CMGC_MAPK_p38_MAPK11_ST	Q00613	HSF1	Q15759	MAPK11	S314	P318T	318	Missense	distal	4	no	37.205	37.259	EPSD	COSMIC	33.886	Up-regulation
CMGC_MAPK_p38_MAPK11_ST	Q00613	HSF1	Q15759	MAPK11	T323	P318T	318	Missense	distal	-5	no	34.256	34.336	EPSD	COSMIC	33.886	Up-regulation
CMGC_MAPK_p38_MAPK11_ST	Q00613	HSF1	Q15759	MAPK11	T323	L330V	330	Missense	distal	7	no	34.256	33.987	EPSD	COSMIC	33.886	Down-regulation
CMGC_MAPK_p38_MAPK11_ST	Q00613	HSF1	Q15759	MAPK11	T323	P327Q	327	Missense	distal	4	no	34.256	33.848	EPSD	COSMIC	33.886	Loss
CMGC_MAPK_p38_MAPK11_ST	Q00613	HSF1	Q15759	MAPK11	S326	L330V	330	Missense	distal	4	no	48.115	47.346	EPSD;PhosphoSitePlus	COSMIC	33.886	Down-regulation
CMGC_MAPK_p38_MAPK11_ST	Q00613	HSF1	Q15759	MAPK11	S326	P327Q	327	Missense	proximal	1	no	48.115	15.973	EPSD;PhosphoSitePlus	COSMIC	33.886	Loss
CMGC_MAPK_p38_MAPK11_ST	Q00613	HSF1	Q15759	MAPK11	T346	T349M	349	Missense	distal	3	no	35.196	34.602	EPSD	COSMIC	33.886	Down-regulation
CMGC_MAPK_p38_MAPK11_ST	Q00613	HSF1	Q15759	MAPK11	T346	P342T	342	Missense	distal	-4	no	35.196	36.317	EPSD	COSMIC	33.886	Up-regulation
CMGC_MAPK_p38_MAPK11_ST	Q00613	HSF1	Q15759	MAPK11	T346	S344C	344	Missense	proximal	-2	no	35.196	34.246	EPSD	COSMIC	33.886	Down-regulation
CMGC_MAPK_p38_MAPK11_ST	Q00613	HSF1	Q15759	MAPK11	S363	S363P	363	Missense	central	0	yes	44.089	0.000	EPSD	COSMIC	33.886	Loss
CMGC_MAPK_p38_MAPK11_ST	Q00613	HSF1	Q15759	MAPK11	S363	P365Q	365	Missense	proximal	2	no	44.089	44.021	EPSD	COSMIC	33.886	Down-regulation
CMGC_MAPK_p38_MAPK11_ST	Q00613	HSF1	Q15759	MAPK11	S363	D356N	356	Missense	distal	-7	no	44.089	44.077	EPSD	COSMIC	33.886	Down-regulation
CMGC_MAPK_p38_MAPK11_ST	Q00613	HSF1	Q15759	MAPK11	S363	P365T	365	Missense	proximal	2	no	44.089	45.472	EPSD	COSMIC	33.886	Up-regulation
CMGC_MAPK_p38_MAPK11_ST	Q00613	HSF1	Q15759	MAPK11	S363	E358K	358	Missense	distal	-5	no	44.089	44.104	EPSD	COSMIC	33.886	Up-regulation
CMGC_MAPK_p38_MAPK11_ST	Q00613	HSF1	Q15759	MAPK11	S363	P365L	365	Missense	proximal	2	no	44.089	44.352	EPSD	COSMIC	33.886	Up-regulation
CMGC_MAPK_p38_MAPK11_ST	Q00613	HSF1	Q15759	MAPK11	T369	S363P	363	Missense	distal	-6	no	45.588	45.493	EPSD	COSMIC	33.886	Down-regulation
CMGC_MAPK_p38_MAPK11_ST	Q00613	HSF1	Q15759	MAPK11	T369	P365Q	365	Missense	distal	-4	no	45.588	44.749	EPSD	COSMIC	33.886	Down-regulation
CMGC_MAPK_p38_MAPK11_ST	Q00613	HSF1	Q15759	MAPK11	T369	P365T	365	Missense	distal	-4	no	45.588	46.709	EPSD	COSMIC	33.886	Up-regulation
CMGC_MAPK_p38_MAPK11_ST	Q00613	HSF1	Q15759	MAPK11	T369	L374F	374	Missense	distal	5	no	45.588	46.120	EPSD	COSMIC	33.886	Up-regulation
CMGC_MAPK_p38_MAPK11_ST	Q00613	HSF1	Q15759	MAPK11	T369	P365L	365	Missense	distal	-4	no	45.588	44.017	EPSD	COSMIC	33.886	Down-regulation
CMGC_MAPK_p38_MAPK11_ST	Q00613	HSF1	Q15759	MAPK11	S419	L417Q	417	Missense	proximal	-2	no	42.318	41.924	EPSD	COSMIC	33.886	Down-regulation
CMGC_MAPK_p38_MAPK11_ST	Q00613	HSF1	Q15759	MAPK11	S419	V422M	422	Missense	distal	3	no	42.318	43.000	EPSD	COSMIC	33.886	Up-regulation
CMGC_MAPK_p38_MAPK11_ST	Q00613	HSF1	Q15759	MAPK11	S419	S419N	419	Missense	central	0	yes	42.318	0.000	EPSD	COSMIC	33.886	Loss
CMGC_MAPK_p38_MAPK11_ST	Q00613	HSF1	Q15759	MAPK11	S444	E447K	447	Missense	distal	3	no	41.001	41.582	EPSD	COSMIC	33.886	Up-regulation
CMGC_MAPK_p38_MAPK11_ST	Q00613	HSF1	Q15759	MAPK11	S458	P452H	452	Missense	distal	-6	no	42.074	41.991	EPSD	COSMIC	33.886	Down-regulation
CMGC_MAPK_p38_MAPK11_ST	Q8N122	RPTOR	Q15759	MAPK11	S696	E689K	689	Missense	distal	-7	no	35.586	35.673	EPSD	COSMIC	33.886	Up-regulation
CMGC_MAPK_p38_MAPK11_ST	Q8N122	RPTOR	Q15759	MAPK11	S696	S696Y	696	Missense	central	0	yes	35.586	0.000	EPSD	COSMIC	33.886	Loss
CMGC_MAPK_p38_MAPK11_ST	Q8N122	RPTOR	Q15759	MAPK11	S696	A693T	693	Missense	distal	-3	no	35.586	35.504	EPSD	COSMIC;GDSC;CCLE	33.886	Down-regulation
CMGC_MAPK_p38_MAPK11_ST	Q8N122	RPTOR	Q15759	MAPK11	S696	G702E	702	Missense	distal	6	no	35.586	35.555	EPSD	COSMIC	33.886	Down-regulation
CMGC_MAPK_p38_MAPK11_ST	Q8N122	RPTOR	Q15759	MAPK11	S696	S696A	696	Missense	central	0	yes	35.586	0.000	EPSD	COSMIC	33.886	Loss
CMGC_MAPK_p38_MAPK11_ST	Q8N122	RPTOR	Q15759	MAPK11	S704	D710N	710	Missense	distal	6	no	33.943	33.955	EPSD	COSMIC	33.886	Up-regulation
CMGC_MAPK_p38_MAPK11_ST	Q8N122	RPTOR	Q15759	MAPK11	S704	R709G	709	Missense	distal	5	no	33.943	34.120	EPSD	COSMIC	33.886	Up-regulation
CMGC_MAPK_p38_MAPK11_ST	Q8N122	RPTOR	Q15759	MAPK11	S704	G702E	702	Missense	proximal	-2	no	33.943	34.324	EPSD	COSMIC	33.886	Up-regulation
CMGC_MAPK_p38_MAPK11_ST	Q8N122	RPTOR	Q15759	MAPK11	T706	P712L	712	Missense	distal	6	no	35.602	35.639	EPSD	COSMIC	33.886	Up-regulation
CMGC_MAPK_p38_MAPK11_ST	Q8N122	RPTOR	Q15759	MAPK11	T706	D710N	710	Missense	distal	4	no	35.602	35.073	EPSD	COSMIC	33.886	Down-regulation
CMGC_MAPK_p38_MAPK11_ST	Q8N122	RPTOR	Q15759	MAPK11	T706	R709G	709	Missense	distal	3	no	35.602	36.162	EPSD	COSMIC	33.886	Up-regulation
CMGC_MAPK_p38_MAPK11_ST	Q8N122	RPTOR	Q15759	MAPK11	T706	G702E	702	Missense	distal	-4	no	35.602	35.634	EPSD	COSMIC	33.886	Up-regulation
CMGC_MAPK_p38_MAPK11_ST	Q8N122	RPTOR	Q15759	MAPK11	S711	R718C	718	Missense	distal	7	no	44.879	43.903	EPSD	COSMIC;CCLE	33.886	Down-regulation
CMGC_MAPK_p38_MAPK11_ST	Q8N122	RPTOR	Q15759	MAPK11	S711	P712L	712	Missense	proximal	1	no	44.879	35.061	EPSD	COSMIC	33.886	Down-regulation
CMGC_MAPK_p38_MAPK11_ST	Q8N122	RPTOR	Q15759	MAPK11	S711	P715S	715	Missense	distal	4	no	44.879	45.283	EPSD	COSMIC	33.886	Up-regulation
CMGC_MAPK_p38_MAPK11_ST	Q8N122	RPTOR	Q15759	MAPK11	S711	D710N	710	Missense	proximal	-1	no	44.879	44.787	EPSD	COSMIC	33.886	Down-regulation
CMGC_MAPK_p38_MAPK11_ST	Q8N122	RPTOR	Q15759	MAPK11	S711	R709G	709	Missense	proximal	-2	no	44.879	44.856	EPSD	COSMIC	33.886	Down-regulation
CMGC_MAPK_p38_MAPK11_ST	Q8N122	RPTOR	Q15759	MAPK11	T714	R718C	718	Missense	distal	4	no	41.037	39.472	EPSD	COSMIC;CCLE	33.886	Down-regulation
CMGC_MAPK_p38_MAPK11_ST	Q8N122	RPTOR	Q15759	MAPK11	T714	P712L	712	Missense	proximal	-2	no	41.037	40.700	EPSD	COSMIC	33.886	Down-regulation
CMGC_MAPK_p38_MAPK11_ST	Q8N122	RPTOR	Q15759	MAPK11	T714	P715S	715	Missense	proximal	1	no	41.037	25.538	EPSD	COSMIC	33.886	Loss
CMGC_MAPK_p38_MAPK11_ST	Q8N122	RPTOR	Q15759	MAPK11	T714	D710N	710	Missense	distal	-4	no	41.037	41.561	EPSD	COSMIC	33.886	Up-regulation
CMGC_MAPK_p38_MAPK11_ST	Q8N122	RPTOR	Q15759	MAPK11	T714	S719Y	719	Missense	distal	5	no	41.037	41.277	EPSD	COSMIC	33.886	Up-regulation
CMGC_MAPK_p38_MAPK11_ST	Q8N122	RPTOR	Q15759	MAPK11	T714	S721N	721	Missense	distal	7	no	41.037	40.390	EPSD	COSMIC	33.886	Down-regulation
CMGC_MAPK_p38_MAPK11_ST	Q8N122	RPTOR	Q15759	MAPK11	T714	V720L	720	Missense	distal	6	no	41.037	41.025	EPSD	COSMIC	33.886	Down-regulation
CMGC_MAPK_p38_MAPK11_ST	Q8N122	RPTOR	Q15759	MAPK11	T714	R709G	709	Missense	distal	-5	no	41.037	41.087	EPSD	COSMIC	33.886	Up-regulation
CMGC_MAPK_p38_MAPK11_ST	Q8N122	RPTOR	Q15759	MAPK11	T731	S738Y	738	Missense	distal	7	no	37.316	36.744	EPSD	COSMIC	33.886	Down-regulation
CMGC_MAPK_p38_MAPK11_ST	Q8N122	RPTOR	Q15759	MAPK11	T731	A730T	730	Missense	proximal	-1	no	37.316	37.635	EPSD	COSMIC	33.886	Up-regulation
CMGC_MAPK_p38_MAPK11_ST	Q8N122	RPTOR	Q15759	MAPK11	T731	T731A	731	Missense	central	0	yes	37.316	0.000	EPSD	COSMIC	33.886	Loss
CMGC_MAPK_p38_MAPK11_ST	Q8N122	RPTOR	Q15759	MAPK11	S771	A765T	765	Missense	distal	-6	no	49.052	49.081	PhosphoSitePlus;EPSD	COSMIC	33.886	Up-regulation
CMGC_MAPK_p38_MAPK11_ST	Q8N122	RPTOR	Q15759	MAPK11	S771	E775Q	775	Missense	distal	4	no	49.052	48.346	PhosphoSitePlus;EPSD	COSMIC	33.886	Down-regulation
CMGC_MAPK_p38_MAPK11_ST	Q8N122	RPTOR	Q15759	MAPK11	S771	S766T	766	Missense	distal	-5	no	49.052	48.973	PhosphoSitePlus;EPSD	COSMIC	33.886	Down-regulation
CMGC_MAPK_p38_MAPK11_ST	Q8N122	RPTOR	Q15759	MAPK11	T853	S854A	854	Missense	proximal	1	no	32.692	39.155	EPSD	COSMIC	33.886	Gain
CMGC_MAPK_p38_MAPK11_ST	Q8N122	RPTOR	Q15759	MAPK11	S863	K867R	867	Missense	distal	4	no	45.457	44.585	EPSD;PhosphoSitePlus	COSMIC	33.886	Down-regulation
CMGC_MAPK_p38_MAPK11_ST	Q8N122	RPTOR	Q15759	MAPK11	S863	G868S	868	Missense	distal	5	no	45.457	44.903	EPSD;PhosphoSitePlus	COSMIC	33.886	Down-regulation
CMGC_MAPK_p38_MAPK11_ST	Q8N122	RPTOR	Q15759	MAPK11	S863	P861L	861	Missense	proximal	-2	no	45.457	45.121	EPSD;PhosphoSitePlus	COSMIC	33.886	Down-regulation
CMGC_MAPK_p38_MAPK11_ST	Q8N122	RPTOR	Q15759	MAPK11	S863	V869M	869	Missense	distal	6	no	45.457	45.419	EPSD;PhosphoSitePlus	COSMIC	33.886	Down-regulation
CMGC_MAPK_p38_MAPK11_ST	Q8N122	RPTOR	Q15759	MAPK11	S863	A862T	862	Missense	proximal	-1	no	45.457	45.777	EPSD;PhosphoSitePlus	COSMIC	33.886	Up-regulation
CMGC_MAPK_p38_MAPK11_ST	Q8N122	RPTOR	Q15759	MAPK11	S877	A874V	874	Missense	distal	-3	no	36.051	36.684	EPSD	COSMIC;GDSC;CCLE	33.886	Up-regulation
CMGC_MAPK_p38_MAPK11_ST	Q8N122	RPTOR	Q15759	MAPK11	S877	P878S	878	Missense	proximal	1	no	36.051	20.552	EPSD	COSMIC	33.886	Loss
CMGC_MAPK_p38_MAPK11_ST	Q8N122	RPTOR	Q15759	MAPK11	S877	P879S	879	Missense	proximal	2	no	36.051	37.239	EPSD	COSMIC	33.886	Up-regulation
CMGC_MAPK_p38_MAPK11_ST	Q8N122	RPTOR	Q15759	MAPK11	S877	A880S	880	Missense	distal	3	no	36.051	37.027	EPSD	COSMIC	33.886	Up-regulation
CMGC_MAPK_p38_MAPK11_ST	Q8N122	RPTOR	Q15759	MAPK11	S877	P878L	878	Missense	proximal	1	no	36.051	26.233	EPSD	COSMIC	33.886	Loss
CMGC_MAPK_p38_MAPK11_ST	Q8N122	RPTOR	Q15759	MAPK11	S886	N890K	890	Missense	distal	4	no	33.841	35.214	EPSD	COSMIC	33.886	Gain
CMGC_MAPK_p38_MAPK11_ST	Q8N122	RPTOR	Q15759	MAPK11	S886	P879S	879	Missense	distal	-7	no	33.841	33.979	EPSD	COSMIC	33.886	Gain
CMGC_MAPK_p38_MAPK11_ST	Q8N122	RPTOR	Q15759	MAPK11	S886	A880S	880	Missense	distal	-6	no	33.841	33.980	EPSD	COSMIC	33.886	Gain
CMGC_MAPK_p38_MAPK11_ST	Q8N122	RPTOR	Q15759	MAPK11	S887	N890K	890	Missense	distal	3	no	42.638	43.361	EPSD	COSMIC	33.886	Up-regulation
CMGC_MAPK_p38_MAPK11_ST	Q8N122	RPTOR	Q15759	MAPK11	S887	T889A	889	Missense	proximal	2	no	42.638	40.057	EPSD	COSMIC	33.886	Down-regulation
CMGC_MAPK_p38_MAPK11_ST	Q8N122	RPTOR	Q15759	MAPK11	S887	D891Y	891	Missense	distal	4	no	42.638	42.288	EPSD	COSMIC	33.886	Down-regulation
CMGC_MAPK_p38_MAPK11_ST	Q8N122	RPTOR	Q15759	MAPK11	S887	A880S	880	Missense	distal	-7	no	42.638	42.805	EPSD	COSMIC	33.886	Up-regulation
CMGC_MAPK_p38_MAPK11_ST	Q8N122	RPTOR	Q15759	MAPK11	S898	R899L	899	Missense	proximal	1	no	-13.238	37.819	EPSD	COSMIC	33.886	Gain
CMGC_MAPK_p38_MAPK11_ST	Q8N122	RPTOR	Q15759	MAPK11	T917	P924T	924	Missense	distal	7	no	46.103	46.078	EPSD	COSMIC	33.886	Down-regulation
CMGC_MAPK_p38_MAPK11_ST	Q8N122	RPTOR	Q15759	MAPK11	T917	Y916C	916	Missense	proximal	-1	no	46.103	45.471	EPSD	COSMIC;GDSC;CCLE	33.886	Down-regulation
CMGC_MAPK_p38_MAPK11_ST	Q8N122	RPTOR	Q15759	MAPK11	T917	P911L	911	Missense	distal	-6	no	46.103	46.041	EPSD	COSMIC	33.886	Down-regulation
CMGC_MAPK_p38_MAPK11_ST	Q8N122	RPTOR	Q15759	MAPK11	T917	G910D	910	Missense	distal	-7	no	46.103	46.126	EPSD	COSMIC	33.886	Up-regulation
CMGC_MAPK_p38_MAPK11_ST	Q8N122	RPTOR	Q15759	MAPK11	T917	Q922R	922	Missense	distal	5	no	46.103	46.305	EPSD	COSMIC	33.886	Up-regulation
CMGC_MAPK_p38_MAPK11_ST	Q01094	E2F1	Q15759	MAPK11	S121	H114Y	114	Missense	distal	-7	no	46.718	46.797	EPSD	COSMIC	33.886	Up-regulation
CMGC_MAPK_p38_MAPK11_ST	Q01094	E2F1	Q15759	MAPK11	S121	R127L	127	Missense	distal	6	no	46.718	46.717	EPSD	COSMIC	33.886	Down-regulation
CMGC_MAPK_p38_MAPK11_ST	Q01094	E2F1	Q15759	MAPK11	S121	G116V	116	Missense	distal	-5	no	46.718	46.488	EPSD	COSMIC	33.886	Down-regulation
CMGC_MAPK_p38_MAPK11_ST	Q01094	E2F1	Q15759	MAPK11	S131	R127L	127	Missense	distal	-4	no	38.340	35.810	EPSD	COSMIC	33.886	Down-regulation
CMGC_MAPK_p38_MAPK11_ST	Q01094	E2F1	Q15759	MAPK11	S307	P312L	312	Missense	distal	5	no	34.651	34.554	EPSD	COSMIC	33.886	Down-regulation
CMGC_MAPK_p38_MAPK11_ST	Q01094	E2F1	Q15759	MAPK11	T311	S318F	318	Missense	distal	7	no	37.432	36.412	EPSD	COSMIC	33.886	Down-regulation
CMGC_MAPK_p38_MAPK11_ST	Q01094	E2F1	Q15759	MAPK11	T311	P312L	312	Missense	proximal	1	no	37.432	27.614	EPSD	COSMIC	33.886	Loss
CMGC_MAPK_p38_MAPK11_ST	Q01094	E2F1	Q15759	MAPK11	S327	I330T	330	Missense	distal	3	no	32.557	34.464	EPSD	COSMIC	33.886	Gain
CMGC_MAPK_p38_MAPK11_ST	Q01094	E2F1	Q15759	MAPK11	S332	S336L	336	Missense	distal	4	no	40.062	38.435	EPSD	COSMIC	33.886	Down-regulation
CMGC_MAPK_p38_MAPK11_ST	Q01094	E2F1	Q15759	MAPK11	S332	I330T	330	Missense	proximal	-2	no	40.062	41.286	EPSD	COSMIC	33.886	Up-regulation
CMGC_MAPK_p38_MAPK11_ST	Q01094	E2F1	Q15759	MAPK11	S332	P335Q	335	Missense	distal	3	no	40.062	39.559	EPSD	COSMIC;GDSC;CCLE	33.886	Down-regulation
CMGC_MAPK_p38_MAPK11_ST	Q01094	E2F1	Q15759	MAPK11	S332	P335S	335	Missense	distal	3	no	40.062	40.525	EPSD	COSMIC	33.886	Up-regulation
CMGC_MAPK_p38_MAPK11_ST	Q01094	E2F1	Q15759	MAPK11	S332	P334L	334	Missense	proximal	2	no	40.062	40.325	EPSD	COSMIC	33.886	Up-regulation
CMGC_MAPK_p38_MAPK11_ST	Q01094	E2F1	Q15759	MAPK11	S337	S341F	341	Missense	distal	4	no	50.382	49.065	EPSD	COSMIC	33.886	Down-regulation
CMGC_MAPK_p38_MAPK11_ST	Q01094	E2F1	Q15759	MAPK11	S337	S336L	336	Missense	proximal	-1	no	50.382	50.083	EPSD	COSMIC	33.886	Down-regulation
CMGC_MAPK_p38_MAPK11_ST	Q01094	E2F1	Q15759	MAPK11	S337	I330T	330	Missense	distal	-7	no	50.382	50.656	EPSD	COSMIC	33.886	Up-regulation
CMGC_MAPK_p38_MAPK11_ST	Q01094	E2F1	Q15759	MAPK11	S337	P335Q	335	Missense	proximal	-2	no	50.382	49.652	EPSD	COSMIC;GDSC;CCLE	33.886	Down-regulation
CMGC_MAPK_p38_MAPK11_ST	Q01094	E2F1	Q15759	MAPK11	S337	P335S	335	Missense	proximal	-2	no	50.382	50.321	EPSD	COSMIC	33.886	Down-regulation
CMGC_MAPK_p38_MAPK11_ST	Q01094	E2F1	Q15759	MAPK11	S337	P334L	334	Missense	distal	-3	no	50.382	50.800	EPSD	COSMIC	33.886	Up-regulation
CMGC_MAPK_p38_MAPK11_ST	Q01094	E2F1	Q15759	MAPK11	S340	S341F	341	Missense	proximal	1	no	35.695	3.761	EPSD	COSMIC	33.886	Loss
CMGC_MAPK_p38_MAPK11_ST	Q01094	E2F1	Q15759	MAPK11	S340	P346S	346	Missense	distal	6	no	35.695	35.687	EPSD	COSMIC;GDSC	33.886	Down-regulation
CMGC_MAPK_p38_MAPK11_ST	Q01094	E2F1	Q15759	MAPK11	S340	S336L	336	Missense	distal	-4	no	35.695	32.406	EPSD	COSMIC	33.886	Loss
CMGC_MAPK_p38_MAPK11_ST	Q01094	E2F1	Q15759	MAPK11	S340	P335Q	335	Missense	distal	-5	no	35.695	35.600	EPSD	COSMIC;GDSC;CCLE	33.886	Down-regulation
CMGC_MAPK_p38_MAPK11_ST	Q01094	E2F1	Q15759	MAPK11	S340	P335S	335	Missense	distal	-5	no	35.695	35.854	EPSD	COSMIC	33.886	Up-regulation
CMGC_MAPK_p38_MAPK11_ST	Q01094	E2F1	Q15759	MAPK11	S340	P334L	334	Missense	distal	-6	no	35.695	35.634	EPSD	COSMIC	33.886	Down-regulation
CMGC_MAPK_p38_MAPK11_ST	Q01094	E2F1	Q15759	MAPK11	S341	S341F	341	Missense	central	0	yes	39.854	0.000	EPSD	COSMIC	33.886	Loss
CMGC_MAPK_p38_MAPK11_ST	Q01094	E2F1	Q15759	MAPK11	S341	P346S	346	Missense	distal	5	no	39.854	39.481	EPSD	COSMIC;GDSC	33.886	Down-regulation
CMGC_MAPK_p38_MAPK11_ST	Q01094	E2F1	Q15759	MAPK11	S341	S336L	336	Missense	distal	-5	no	39.854	39.555	EPSD	COSMIC	33.886	Down-regulation
CMGC_MAPK_p38_MAPK11_ST	Q01094	E2F1	Q15759	MAPK11	S341	P335Q	335	Missense	distal	-6	no	39.854	39.801	EPSD	COSMIC;GDSC;CCLE	33.886	Down-regulation
CMGC_MAPK_p38_MAPK11_ST	Q01094	E2F1	Q15759	MAPK11	S341	P335S	335	Missense	distal	-6	no	39.854	39.949	EPSD	COSMIC	33.886	Up-regulation
CMGC_MAPK_p38_MAPK11_ST	Q01094	E2F1	Q15759	MAPK11	S341	P334L	334	Missense	distal	-7	no	39.854	39.768	EPSD	COSMIC	33.886	Down-regulation
CMGC_MAPK_p38_MAPK11_ST	Q01094	E2F1	Q15759	MAPK11	S349	P346S	346	Missense	distal	-3	no	35.962	35.820	EPSD	COSMIC;GDSC	33.886	Down-regulation
CMGC_MAPK_p38_MAPK11_ST	Q01094	E2F1	Q15759	MAPK11	S349	L350V	350	Missense	proximal	1	no	35.962	5.412	EPSD	COSMIC	33.886	Loss
CMGC_MAPK_p38_MAPK11_ST	Q01094	E2F1	Q15759	MAPK11	S352	P346S	346	Missense	distal	-6	no	35.108	35.203	EPSD	COSMIC;GDSC	33.886	Up-regulation
CMGC_MAPK_p38_MAPK11_ST	Q01094	E2F1	Q15759	MAPK11	S352	L350V	350	Missense	proximal	-2	no	35.108	34.960	EPSD	COSMIC	33.886	Down-regulation
CMGC_MAPK_p38_MAPK11_ST	Q01094	E2F1	Q15759	MAPK11	S375	S382L	382	Missense	distal	7	no	42.829	42.007	EPSD	COSMIC	33.886	Down-regulation
CMGC_MAPK_p38_MAPK11_ST	Q01094	E2F1	Q15759	MAPK11	S403	P404S	404	Missense	proximal	1	no	47.567	32.068	EPSD;PhosphoSitePlus	COSMIC	33.886	Loss
CMGC_MAPK_p38_MAPK11_ST	P00533	EGFR	Q15759	MAPK11	S50	D46N	46	Missense	distal	-4	no	33.387	33.911	EPSD	COSMIC	33.886	Gain
CMGC_MAPK_p38_MAPK11_ST	P00533	EGFR	Q15759	MAPK11	S227	G221V	221	Missense	distal	-6	no	34.848	34.728	EPSD	COSMIC	33.886	Down-regulation
CMGC_MAPK_p38_MAPK11_ST	P00533	EGFR	Q15759	MAPK11	S227	R222H	222	Missense	distal	-5	no	34.848	34.766	EPSD	COSMIC	33.886	Down-regulation
CMGC_MAPK_p38_MAPK11_ST	P00533	EGFR	Q15759	MAPK11	S227	G221W	221	Missense	distal	-6	no	34.848	34.814	EPSD	COSMIC	33.886	Down-regulation
CMGC_MAPK_p38_MAPK11_ST	P00533	EGFR	Q15759	MAPK11	S227	S227Y	227	Missense	central	0	yes	34.848	0.000	EPSD	COSMIC	33.886	Loss
CMGC_MAPK_p38_MAPK11_ST	P00533	EGFR	Q15759	MAPK11	S227	G225C	225	Missense	proximal	-2	no	34.848	34.592	EPSD	COSMIC	33.886	Down-regulation
CMGC_MAPK_p38_MAPK11_ST	P00533	EGFR	Q15759	MAPK11	S227	S220F	220	Missense	distal	-7	no	34.848	34.600	EPSD	COSMIC	33.886	Down-regulation
CMGC_MAPK_p38_MAPK11_ST	P00533	EGFR	Q15759	MAPK11	S227	C231S	231	Missense	distal	4	no	34.848	37.193	EPSD	COSMIC	33.886	Up-regulation
CMGC_MAPK_p38_MAPK11_ST	P00533	EGFR	Q15759	MAPK11	S511	A508V	508	Missense	distal	-3	no	42.006	42.640	EPSD	COSMIC	33.886	Up-regulation
CMGC_MAPK_p38_MAPK11_ST	P00533	EGFR	Q15759	MAPK11	S511	L509F	509	Missense	proximal	-2	no	42.006	41.171	EPSD	COSMIC	33.886	Down-regulation
CMGC_MAPK_p38_MAPK11_ST	P00533	EGFR	Q15759	MAPK11	S511	S511Y	511	Missense	central	0	yes	42.006	0.000	EPSD	COSMIC	33.886	Loss
CMGC_MAPK_p38_MAPK11_ST	P00533	EGFR	Q15759	MAPK11	T693	A698V	698	Missense	distal	5	no	43.228	43.879	EPSD	COSMIC	33.886	Up-regulation
CMGC_MAPK_p38_MAPK11_ST	P00533	EGFR	Q15759	MAPK11	T693	P691T	691	Missense	proximal	-2	no	43.228	43.362	EPSD	COSMIC	33.886	Up-regulation
CMGC_MAPK_p38_MAPK11_ST	P00533	EGFR	Q15759	MAPK11	T693	L688P	688	Missense	distal	-5	no	43.228	43.367	EPSD	COSMIC	33.886	Up-regulation
CMGC_MAPK_p38_MAPK11_ST	P00533	EGFR	Q15759	MAPK11	T693	P699S	699	Missense	distal	6	no	43.228	43.220	EPSD	COSMIC	33.886	Down-regulation
CMGC_MAPK_p38_MAPK11_ST	P00533	EGFR	Q15759	MAPK11	T693	V689M	689	Missense	distal	-4	no	43.228	43.148	EPSD	COSMIC	33.886	Down-regulation
CMGC_MAPK_p38_MAPK11_ST	P00533	EGFR	Q15759	MAPK11	T693	N700Y	700	Missense	distal	7	no	43.228	43.303	EPSD	COSMIC	33.886	Up-regulation
CMGC_MAPK_p38_MAPK11_ST	P00533	EGFR	Q15759	MAPK11	T693	L692P	692	Missense	proximal	-1	no	43.228	43.582	EPSD	COSMIC	33.886	Up-regulation
CMGC_MAPK_p38_MAPK11_ST	P00533	EGFR	Q15759	MAPK11	T693	P694S	694	Missense	proximal	1	no	43.228	27.729	EPSD	COSMIC	33.886	Loss
CMGC_MAPK_p38_MAPK11_ST	P00533	EGFR	Q15759	MAPK11	T693	N700S	700	Missense	distal	7	no	43.228	43.875	EPSD	COSMIC	33.886	Up-regulation
CMGC_MAPK_p38_MAPK11_ST	P00533	EGFR	Q15759	MAPK11	T693	E690K	690	Missense	distal	-3	no	43.228	43.262	EPSD	COSMIC	33.886	Up-regulation
CMGC_MAPK_p38_MAPK11_ST	P00533	EGFR	Q15759	MAPK11	T693	P691S	691	Missense	proximal	-2	no	43.228	43.166	EPSD	COSMIC	33.886	Down-regulation
CMGC_MAPK_p38_MAPK11_ST	P00533	EGFR	Q15759	MAPK11	T693	V689L	689	Missense	distal	-4	no	43.228	42.973	EPSD	COSMIC	33.886	Down-regulation
CMGC_MAPK_p38_MAPK11_ST	P00533	EGFR	Q15759	MAPK11	T693	E697D	697	Missense	distal	4	no	43.228	42.580	EPSD	COSMIC	33.886	Down-regulation
CMGC_MAPK_p38_MAPK11_ST	P00533	EGFR	Q15759	MAPK11	T693	P694L	694	Missense	proximal	1	no	43.228	33.410	EPSD	COSMIC	33.886	Loss
CMGC_MAPK_p38_MAPK11_ST	P00533	EGFR	Q15759	MAPK11	T693	L688F	688	Missense	distal	-5	no	43.228	43.234	EPSD	COSMIC	33.886	Up-regulation
CMGC_MAPK_p38_MAPK11_ST	P00533	EGFR	Q15759	MAPK11	T693	N700D	700	Missense	distal	7	no	43.228	43.297	EPSD	COSMIC	33.886	Up-regulation
CMGC_MAPK_p38_MAPK11_ST	P00533	EGFR	Q15759	MAPK11	T693	S695G	695	Missense	proximal	2	no	43.228	41.189	EPSD	COSMIC	33.886	Down-regulation
CMGC_MAPK_p38_MAPK11_ST	P00533	EGFR	Q15759	MAPK11	T693	R686S	686	Missense	distal	-7	no	43.228	43.323	EPSD	COSMIC	33.886	Up-regulation
CMGC_MAPK_p38_MAPK11_ST	P00533	EGFR	Q15759	MAPK11	T693	T693A	693	Missense	central	0	yes	43.228	0.000	EPSD	COSMIC	33.886	Loss
CMGC_MAPK_p38_MAPK11_ST	P00533	EGFR	Q15759	MAPK11	T693	E690V	690	Missense	distal	-3	no	43.228	44.328	EPSD	COSMIC	33.886	Up-regulation
CMGC_MAPK_p38_MAPK11_ST	P00533	EGFR	Q15759	MAPK11	T693	L692F	692	Missense	proximal	-1	no	43.228	42.659	EPSD	COSMIC	33.886	Down-regulation
CMGC_MAPK_p38_MAPK11_ST	P00533	EGFR	Q15759	MAPK11	T693	G696R	696	Missense	distal	3	no	43.228	42.667	EPSD	COSMIC	33.886	Down-regulation
CMGC_MAPK_p38_MAPK11_ST	P00533	EGFR	Q15759	MAPK11	T693	G696E	696	Missense	distal	3	no	43.228	42.965	EPSD	COSMIC	33.886	Down-regulation
CMGC_MAPK_p38_MAPK11_ST	P00533	EGFR	Q15759	MAPK11	S752	L747P	747	Missense	distal	-5	no	45.508	45.648	EPSD	COSMIC	33.886	Up-regulation
CMGC_MAPK_p38_MAPK11_ST	P00533	EGFR	Q15759	MAPK11	S752	L747F	747	Missense	distal	-5	no	45.508	45.515	EPSD	COSMIC	33.886	Up-regulation
CMGC_MAPK_p38_MAPK11_ST	P00533	EGFR	Q15759	MAPK11	S752	L747H	747	Missense	distal	-5	no	45.508	45.514	EPSD	COSMIC	33.886	Up-regulation
CMGC_MAPK_p38_MAPK11_ST	P00533	EGFR	Q15759	MAPK11	S752	L747S	747	Missense	distal	-5	no	45.508	45.807	EPSD	COSMIC	33.886	Up-regulation
CMGC_MAPK_p38_MAPK11_ST	P00533	EGFR	Q15759	MAPK11	S752	A750P	750	Missense	proximal	-2	no	45.508	45.839	EPSD	COSMIC	33.886	Up-regulation
CMGC_MAPK_p38_MAPK11_ST	P00533	EGFR	Q15759	MAPK11	S752	R748K	748	Missense	distal	-4	no	45.508	46.120	EPSD	COSMIC	33.886	Up-regulation
CMGC_MAPK_p38_MAPK11_ST	P00533	EGFR	Q15759	MAPK11	S752	I759V	759	Missense	distal	7	no	45.508	45.731	EPSD	COSMIC	33.886	Up-regulation
CMGC_MAPK_p38_MAPK11_ST	P00533	EGFR	Q15759	MAPK11	S752	K754Q	754	Missense	proximal	2	no	45.508	45.074	EPSD	COSMIC	33.886	Down-regulation
CMGC_MAPK_p38_MAPK11_ST	P00533	EGFR	Q15759	MAPK11	S752	T751A	751	Missense	proximal	-1	no	45.508	45.189	EPSD	COSMIC	33.886	Down-regulation
CMGC_MAPK_p38_MAPK11_ST	P00533	EGFR	Q15759	MAPK11	S752	E758G	758	Missense	distal	6	no	45.508	45.539	EPSD	COSMIC	33.886	Up-regulation
CMGC_MAPK_p38_MAPK11_ST	P00533	EGFR	Q15759	MAPK11	S752	K757N	757	Missense	distal	5	no	45.508	45.805	EPSD	COSMIC	33.886	Up-regulation
CMGC_MAPK_p38_MAPK11_ST	P00533	EGFR	Q15759	MAPK11	S752	S752Y	752	Missense	central	0	yes	45.508	0.000	EPSD	COSMIC	33.886	Loss
CMGC_MAPK_p38_MAPK11_ST	P00533	EGFR	Q15759	MAPK11	S752	T751I	751	Missense	proximal	-1	no	45.508	43.992	EPSD	COSMIC;GDSC;CCLE	33.886	Down-regulation
CMGC_MAPK_p38_MAPK11_ST	P00533	EGFR	Q15759	MAPK11	S752	E746V	746	Missense	distal	-6	no	45.508	45.322	EPSD	COSMIC	33.886	Down-regulation
CMGC_MAPK_p38_MAPK11_ST	P00533	EGFR	Q15759	MAPK11	S752	A750T	750	Missense	proximal	-2	no	45.508	45.974	EPSD	COSMIC	33.886	Up-regulation
CMGC_MAPK_p38_MAPK11_ST	P00533	EGFR	Q15759	MAPK11	S752	S752F	752	Missense	central	0	yes	45.508	0.000	EPSD	COSMIC	33.886	Loss
CMGC_MAPK_p38_MAPK11_ST	P00533	EGFR	Q15759	MAPK11	S752	E746A	746	Missense	distal	-6	no	45.508	45.470	EPSD	COSMIC;GDSC	33.886	Down-regulation
CMGC_MAPK_p38_MAPK11_ST	P00533	EGFR	Q15759	MAPK11	S752	A755D	755	Missense	distal	3	no	45.508	46.241	EPSD	COSMIC;CCLE	33.886	Up-regulation
CMGC_MAPK_p38_MAPK11_ST	P00533	EGFR	Q15759	MAPK11	S752	K754R	754	Missense	proximal	2	no	45.508	45.584	EPSD	COSMIC	33.886	Up-regulation
CMGC_MAPK_p38_MAPK11_ST	P00533	EGFR	Q15759	MAPK11	S752	E749K	749	Missense	distal	-3	no	45.508	45.543	EPSD	COSMIC	33.886	Up-regulation
CMGC_MAPK_p38_MAPK11_ST	P00533	EGFR	Q15759	MAPK11	S752	T751L	751	Missense	proximal	-1	no	45.508	44.799	EPSD	COSMIC	33.886	Down-regulation
CMGC_MAPK_p38_MAPK11_ST	P00533	EGFR	Q15759	MAPK11	S752	E758K	758	Missense	distal	6	no	45.508	45.507	EPSD	COSMIC	33.886	Down-regulation
CMGC_MAPK_p38_MAPK11_ST	P00533	EGFR	Q15759	MAPK11	S752	K745R	745	Missense	distal	-7	no	45.508	45.430	EPSD	COSMIC	33.886	Down-regulation
CMGC_MAPK_p38_MAPK11_ST	P00533	EGFR	Q15759	MAPK11	S752	E746I	746	Missense	distal	-6	no	45.508	45.276	EPSD	COSMIC	33.886	Down-regulation
CMGC_MAPK_p38_MAPK11_ST	P00533	EGFR	Q15759	MAPK11	S752	A755T	755	Missense	distal	3	no	45.508	46.267	EPSD	COSMIC	33.886	Up-regulation
CMGC_MAPK_p38_MAPK11_ST	P00533	EGFR	Q15759	MAPK11	S752	K754A	754	Missense	proximal	2	no	45.508	43.943	EPSD	COSMIC	33.886	Down-regulation
CMGC_MAPK_p38_MAPK11_ST	P00533	EGFR	Q15759	MAPK11	S752	N756S	756	Missense	distal	4	no	45.508	46.790	EPSD	COSMIC	33.886	Up-regulation
CMGC_MAPK_p38_MAPK11_ST	P00533	EGFR	Q15759	MAPK11	S752	N756Y	756	Missense	distal	4	no	45.508	45.688	EPSD	COSMIC	33.886	Up-regulation
CMGC_MAPK_p38_MAPK11_ST	P00533	EGFR	Q15759	MAPK11	S752	K757R	757	Missense	distal	5	no	45.508	45.584	EPSD	COSMIC	33.886	Up-regulation
CMGC_MAPK_p38_MAPK11_ST	P00533	EGFR	Q15759	MAPK11	S752	A755G	755	Missense	distal	3	no	45.508	46.266	EPSD	COSMIC	33.886	Up-regulation
CMGC_MAPK_p38_MAPK11_ST	P00533	EGFR	Q15759	MAPK11	S752	E746G	746	Missense	distal	-6	no	45.508	45.442	EPSD	COSMIC	33.886	Down-regulation
CMGC_MAPK_p38_MAPK11_ST	P00533	EGFR	Q15759	MAPK11	S752	E749V	749	Missense	distal	-3	no	45.508	46.609	EPSD	COSMIC	33.886	Up-regulation
CMGC_MAPK_p38_MAPK11_ST	P00533	EGFR	Q15759	MAPK11	S752	E749G	749	Missense	distal	-3	no	45.508	45.366	EPSD	COSMIC	33.886	Down-regulation
CMGC_MAPK_p38_MAPK11_ST	P00533	EGFR	Q15759	MAPK11	S752	S752P	752	Missense	central	0	yes	45.508	0.000	EPSD	COSMIC	33.886	Loss
CMGC_MAPK_p38_MAPK11_ST	P00533	EGFR	Q15759	MAPK11	S752	E758D	758	Missense	distal	6	no	45.508	45.540	EPSD	COSMIC	33.886	Up-regulation
CMGC_MAPK_p38_MAPK11_ST	P00533	EGFR	Q15759	MAPK11	S752	K745T	745	Missense	distal	-7	no	45.508	45.504	EPSD	COSMIC	33.886	Down-regulation
CMGC_MAPK_p38_MAPK11_ST	P00533	EGFR	Q15759	MAPK11	S752	E746K	746	Missense	distal	-6	no	45.508	45.548	EPSD	COSMIC;GDSC	33.886	Up-regulation
CMGC_MAPK_p38_MAPK11_ST	P00533	EGFR	Q15759	MAPK11	S752	A755V	755	Missense	distal	3	no	45.508	44.990	EPSD	COSMIC	33.886	Down-regulation
CMGC_MAPK_p38_MAPK11_ST	P00533	EGFR	Q15759	MAPK11	S752	L747V	747	Missense	distal	-5	no	45.508	45.416	EPSD	COSMIC	33.886	Down-regulation
CMGC_MAPK_p38_MAPK11_ST	P00533	EGFR	Q15759	MAPK11	S752	T751P	751	Missense	proximal	-1	no	45.508	45.153	EPSD	COSMIC	33.886	Down-regulation
CMGC_MAPK_p38_MAPK11_ST	P00533	EGFR	Q15759	MAPK11	S752	R748I	748	Missense	distal	-4	no	45.508	43.032	EPSD	COSMIC	33.886	Down-regulation
CMGC_MAPK_p38_MAPK11_ST	P00533	EGFR	Q15759	MAPK11	S752	K757M	757	Missense	distal	5	no	45.508	45.389	EPSD	COSMIC	33.886	Down-regulation
CMGC_MAPK_p38_MAPK11_ST	P00533	EGFR	Q15759	MAPK11	S752	P753F	753	Missense	proximal	1	no	45.508	-1.924	EPSD	COSMIC	33.886	Loss
CMGC_MAPK_p38_MAPK11_ST	P00533	EGFR	Q15759	MAPK11	S991	F997L	997	Missense	distal	6	no	37.298	37.268	EPSD	COSMIC	33.886	Down-regulation
CMGC_MAPK_p38_MAPK11_ST	P00533	EGFR	Q15759	MAPK11	S991	D984N	984	Missense	distal	-7	no	37.298	37.286	EPSD	COSMIC	33.886	Down-regulation
CMGC_MAPK_p38_MAPK11_ST	P00533	EGFR	Q15759	MAPK11	S991	M987R	987	Missense	distal	-4	no	37.298	39.653	EPSD	COSMIC	33.886	Up-regulation
CMGC_MAPK_p38_MAPK11_ST	P00533	EGFR	Q15759	MAPK11	S1026	S1025T	1025	Missense	proximal	-1	no	47.162	47.572	EPSD	COSMIC	33.886	Up-regulation
CMGC_MAPK_p38_MAPK11_ST	P00533	EGFR	Q15759	MAPK11	S1026	P1027S	1027	Missense	proximal	1	no	47.162	31.663	EPSD	COSMIC	33.886	Loss
CMGC_MAPK_p38_MAPK11_ST	P00533	EGFR	Q15759	MAPK11	S1026	P1019S	1019	Missense	distal	-7	no	47.162	47.300	EPSD	COSMIC	33.886	Up-regulation
CMGC_MAPK_p38_MAPK11_ST	P00533	EGFR	Q15759	MAPK11	S1026	G1022S	1022	Missense	distal	-4	no	47.162	49.166	EPSD	COSMIC	33.886	Up-regulation
CMGC_MAPK_p38_MAPK11_ST	P00533	EGFR	Q15759	MAPK11	S1026	S1028L	1028	Missense	proximal	2	no	47.162	46.237	EPSD	COSMIC	33.886	Down-regulation
CMGC_MAPK_p38_MAPK11_ST	P00533	EGFR	Q15759	MAPK11	S1026	Q1020H	1020	Missense	distal	-6	no	47.162	47.132	EPSD	COSMIC	33.886	Down-regulation
CMGC_MAPK_p38_MAPK11_ST	P00533	EGFR	Q15759	MAPK11	T1032	S1025T	1025	Missense	distal	-7	no	35.865	35.843	EPSD	COSMIC	33.886	Down-regulation
CMGC_MAPK_p38_MAPK11_ST	P00533	EGFR	Q15759	MAPK11	T1032	P1027S	1027	Missense	distal	-5	no	35.865	36.024	EPSD	COSMIC	33.886	Up-regulation
CMGC_MAPK_p38_MAPK11_ST	P00533	EGFR	Q15759	MAPK11	T1032	S1036R	1036	Missense	distal	4	no	35.865	35.084	EPSD	COSMIC	33.886	Down-regulation
CMGC_MAPK_p38_MAPK11_ST	P00533	EGFR	Q15759	MAPK11	T1032	S1028L	1028	Missense	distal	-4	no	35.865	32.577	EPSD	COSMIC	33.886	Loss
CMGC_MAPK_p38_MAPK11_ST	P00533	EGFR	Q15759	MAPK11	T1032	L1034I	1034	Missense	proximal	2	no	35.865	33.822	EPSD	COSMIC	33.886	Loss
CMGC_MAPK_p38_MAPK11_ST	P00533	EGFR	Q15759	MAPK11	S1037	T1041A	1041	Missense	distal	4	no	36.856	36.824	EPSD	COSMIC	33.886	Down-regulation
CMGC_MAPK_p38_MAPK11_ST	P00533	EGFR	Q15759	MAPK11	S1037	S1036R	1036	Missense	proximal	-1	no	36.856	36.835	EPSD	COSMIC	33.886	Down-regulation
CMGC_MAPK_p38_MAPK11_ST	P00533	EGFR	Q15759	MAPK11	S1037	L1034I	1034	Missense	distal	-3	no	36.856	37.732	EPSD	COSMIC	33.886	Up-regulation
CMGC_MAPK_p38_MAPK11_ST	P00533	EGFR	Q15759	MAPK11	S1039	T1041A	1041	Missense	proximal	2	no	46.998	44.416	PhosphoSitePlus;EPSD	COSMIC	33.886	Down-regulation
CMGC_MAPK_p38_MAPK11_ST	P00533	EGFR	Q15759	MAPK11	S1039	S1036R	1036	Missense	distal	-3	no	46.998	47.384	PhosphoSitePlus;EPSD	COSMIC	33.886	Up-regulation
CMGC_MAPK_p38_MAPK11_ST	P00533	EGFR	Q15759	MAPK11	S1039	L1034I	1034	Missense	distal	-5	no	46.998	46.908	PhosphoSitePlus;EPSD	COSMIC	33.886	Down-regulation
CMGC_MAPK_p38_MAPK11_ST	P00533	EGFR	Q15759	MAPK11	S1039	S1045F	1045	Missense	distal	6	no	46.998	47.073	PhosphoSitePlus;EPSD	COSMIC	33.886	Up-regulation
CMGC_MAPK_p38_MAPK11_ST	P00533	EGFR	Q15759	MAPK11	S1039	T1046I	1046	Missense	distal	7	no	46.998	46.050	PhosphoSitePlus;EPSD	COSMIC	33.886	Down-regulation
CMGC_MAPK_p38_MAPK11_ST	P00533	EGFR	Q15759	MAPK11	T1041	A1048V	1048	Missense	distal	7	no	45.985	45.594	EPSD;PhosphoSitePlus	COSMIC;GDSC;CCLE	33.886	Down-regulation
CMGC_MAPK_p38_MAPK11_ST	P00533	EGFR	Q15759	MAPK11	T1041	T1041A	1041	Missense	central	0	yes	45.985	0.000	EPSD;PhosphoSitePlus	COSMIC	33.886	Loss
CMGC_MAPK_p38_MAPK11_ST	P00533	EGFR	Q15759	MAPK11	T1041	S1036R	1036	Missense	distal	-5	no	45.985	45.774	EPSD;PhosphoSitePlus	COSMIC	33.886	Down-regulation
CMGC_MAPK_p38_MAPK11_ST	P00533	EGFR	Q15759	MAPK11	T1041	V1047M	1047	Missense	distal	6	no	45.985	45.946	EPSD;PhosphoSitePlus	COSMIC	33.886	Down-regulation
CMGC_MAPK_p38_MAPK11_ST	P00533	EGFR	Q15759	MAPK11	T1041	L1034I	1034	Missense	distal	-7	no	45.985	45.914	EPSD;PhosphoSitePlus	COSMIC	33.886	Down-regulation
CMGC_MAPK_p38_MAPK11_ST	P00533	EGFR	Q15759	MAPK11	T1041	S1045F	1045	Missense	distal	4	no	45.985	44.668	EPSD;PhosphoSitePlus	COSMIC	33.886	Down-regulation
CMGC_MAPK_p38_MAPK11_ST	P00533	EGFR	Q15759	MAPK11	T1041	A1048S	1048	Missense	distal	7	no	45.985	46.684	EPSD;PhosphoSitePlus	COSMIC	33.886	Up-regulation
CMGC_MAPK_p38_MAPK11_ST	P00533	EGFR	Q15759	MAPK11	T1041	A1048T	1048	Missense	distal	7	no	45.985	46.318	EPSD;PhosphoSitePlus	COSMIC	33.886	Up-regulation
CMGC_MAPK_p38_MAPK11_ST	P00533	EGFR	Q15759	MAPK11	T1041	T1046I	1046	Missense	distal	5	no	45.985	46.490	EPSD;PhosphoSitePlus	COSMIC	33.886	Up-regulation
CMGC_MAPK_p38_MAPK11_ST	Q8IW41	MAPKAPK5	Q15759	MAPK11	T182	Q184E	184	Missense	proximal	2	no	48.021	47.887	PhosphoSitePlus	COSMIC	33.886	Down-regulation
CMGC_MAPK_p38_MAPK11_ST	Q8IW41	MAPKAPK5	Q15759	MAPK11	T182	T186I	186	Missense	distal	4	no	48.021	45.568	PhosphoSitePlus	COSMIC	33.886	Down-regulation
CMGC_MAPK_p38_MAPK11_ST	Q8IW41	MAPKAPK5	Q15759	MAPK11	T186	Q184E	184	Missense	proximal	-2	no	41.298	41.653	EPSD	COSMIC	33.886	Up-regulation
CMGC_MAPK_p38_MAPK11_ST	Q8IW41	MAPKAPK5	Q15759	MAPK11	T186	T186I	186	Missense	central	0	yes	41.298	0.000	EPSD	COSMIC	33.886	Loss
CMGC_MAPK_p38_MAPK11_ST	P30305	CDC25B	Q15759	MAPK11	S50	A47P	47	Missense	distal	-3	no	35.045	34.774	EPSD	COSMIC	33.886	Down-regulation
CMGC_MAPK_p38_MAPK11_ST	P30305	CDC25B	Q15759	MAPK11	S50	P51L	51	Missense	proximal	1	no	35.045	25.227	EPSD	COSMIC	33.886	Loss
CMGC_MAPK_p38_MAPK11_ST	P30305	CDC25B	Q15759	MAPK11	S50	Q57R	57	Missense	distal	7	no	35.045	35.291	EPSD	COSMIC	33.886	Up-regulation
CMGC_MAPK_p38_MAPK11_ST	P30305	CDC25B	Q15759	MAPK11	S50	A48T	48	Missense	proximal	-2	no	35.045	35.510	EPSD	COSMIC	33.886	Up-regulation
CMGC_MAPK_p38_MAPK11_ST	P30305	CDC25B	Q15759	MAPK11	T54	A47P	47	Missense	distal	-7	no	35.036	35.063	EPSD	COSMIC	33.886	Up-regulation
CMGC_MAPK_p38_MAPK11_ST	P30305	CDC25B	Q15759	MAPK11	T54	P51L	51	Missense	distal	-3	no	35.036	35.453	EPSD	COSMIC	33.886	Up-regulation
CMGC_MAPK_p38_MAPK11_ST	P30305	CDC25B	Q15759	MAPK11	T54	Q57R	57	Missense	distal	3	no	35.036	35.223	EPSD	COSMIC	33.886	Up-regulation
CMGC_MAPK_p38_MAPK11_ST	P30305	CDC25B	Q15759	MAPK11	T54	A48T	48	Missense	distal	-6	no	35.036	35.064	EPSD	COSMIC	33.886	Up-regulation
CMGC_MAPK_p38_MAPK11_ST	P30305	CDC25B	Q15759	MAPK11	T69	E68K	68	Missense	proximal	-1	no	38.212	38.143	EPSD	COSMIC	33.886	Down-regulation
CMGC_MAPK_p38_MAPK11_ST	P30305	CDC25B	Q15759	MAPK11	T69	Q73H	73	Missense	distal	4	no	38.212	37.364	EPSD	COSMIC	33.886	Down-regulation
CMGC_MAPK_p38_MAPK11_ST	P30305	CDC25B	Q15759	MAPK11	S115	A109V	109	Missense	distal	-6	no	53.047	52.900	EPSD	COSMIC	33.886	Down-regulation
CMGC_MAPK_p38_MAPK11_ST	P30305	CDC25B	Q15759	MAPK11	S117	A124E	124	Missense	distal	7	no	43.493	43.953	EPSD	COSMIC	33.886	Up-regulation
CMGC_MAPK_p38_MAPK11_ST	P30305	CDC25B	Q15759	MAPK11	S160	V162L	162	Missense	proximal	2	no	34.688	35.954	EPSD	COSMIC	33.886	Up-regulation
CMGC_MAPK_p38_MAPK11_ST	P30305	CDC25B	Q15759	MAPK11	S186	A184V	184	Missense	proximal	-2	no	36.692	36.539	EPSD	COSMIC	33.886	Down-regulation
CMGC_MAPK_p38_MAPK11_ST	P30305	CDC25B	Q15759	MAPK11	S186	S188R	188	Missense	proximal	2	no	36.692	35.947	EPSD	COSMIC	33.886	Down-regulation
CMGC_MAPK_p38_MAPK11_ST	P30305	CDC25B	Q15759	MAPK11	S238	R241C	241	Missense	distal	3	no	38.938	37.662	EPSD	COSMIC	33.886	Down-regulation
CMGC_MAPK_p38_MAPK11_ST	P30305	CDC25B	Q15759	MAPK11	S238	L237H	237	Missense	proximal	-1	no	38.938	38.544	EPSD	COSMIC	33.886	Down-regulation
CMGC_MAPK_p38_MAPK11_ST	P30305	CDC25B	Q15759	MAPK11	S249	S249R	249	Missense	central	0	yes	45.401	0.000	PhosphoSitePlus	COSMIC	33.886	Loss
CMGC_MAPK_p38_MAPK11_ST	P30305	CDC25B	Q15759	MAPK11	S249	F256L	256	Missense	distal	7	no	45.401	45.599	PhosphoSitePlus	COSMIC;GDSC;CCLE	33.886	Up-regulation
CMGC_MAPK_p38_MAPK11_ST	P30305	CDC25B	Q15759	MAPK11	S249	A252V	252	Missense	distal	3	no	45.401	44.883	PhosphoSitePlus	COSMIC	33.886	Down-regulation
CMGC_MAPK_p38_MAPK11_ST	P30305	CDC25B	Q15759	MAPK11	S249	S249G	249	Missense	central	0	yes	45.401	0.000	PhosphoSitePlus	COSMIC	33.886	Loss
CMGC_MAPK_p38_MAPK11_ST	P30305	CDC25B	Q15759	MAPK11	S249	R255C	255	Missense	distal	6	no	45.401	45.454	PhosphoSitePlus	COSMIC	33.886	Up-regulation
CMGC_MAPK_p38_MAPK11_ST	P30305	CDC25B	Q15759	MAPK11	S321	S323N	323	Missense	proximal	2	no	45.485	45.272	EPSD	COSMIC	33.886	Down-regulation
CMGC_MAPK_p38_MAPK11_ST	P30305	CDC25B	Q15759	MAPK11	S321	P325L	325	Missense	distal	4	no	45.485	44.262	EPSD	COSMIC	33.886	Down-regulation
CMGC_MAPK_p38_MAPK11_ST	P30305	CDC25B	Q15759	MAPK11	S321	R320G	320	Missense	proximal	-1	no	45.485	45.600	EPSD	COSMIC	33.886	Up-regulation
CMGC_MAPK_p38_MAPK11_ST	P30305	CDC25B	Q15759	MAPK11	S321	S321F	321	Missense	central	0	yes	45.485	0.000	EPSD	COSMIC	33.886	Loss
CMGC_MAPK_p38_MAPK11_ST	P30305	CDC25B	Q15759	MAPK11	S321	C315W	315	Missense	distal	-6	no	45.485	45.581	EPSD	COSMIC;GDSC	33.886	Up-regulation
CMGC_MAPK_p38_MAPK11_ST	P30305	CDC25B	Q15759	MAPK11	S321	P322L	322	Missense	proximal	1	no	45.485	35.667	EPSD	COSMIC	33.886	Down-regulation
CMGC_MAPK_p38_MAPK11_ST	P30305	CDC25B	Q15759	MAPK11	S321	R317W	317	Missense	distal	-4	no	45.485	43.717	EPSD	COSMIC	33.886	Down-regulation
CMGC_MAPK_p38_MAPK11_ST	P30305	CDC25B	Q15759	MAPK11	T344	D343G	343	Missense	proximal	-1	no	33.833	33.902	EPSD	COSMIC	33.886	Gain
CMGC_MAPK_p38_MAPK11_ST	P30305	CDC25B	Q15759	MAPK11	T355	R352Q	352	Missense	distal	-3	no	40.945	40.771	EPSD	COSMIC	33.886	Down-regulation
CMGC_MAPK_p38_MAPK11_ST	P30305	CDC25B	Q15759	MAPK11	T355	R350T	350	Missense	distal	-5	no	40.945	41.077	EPSD	COSMIC	33.886	Up-regulation
CMGC_MAPK_p38_MAPK11_ST	P30305	CDC25B	Q15759	MAPK11	S375	S373N	373	Missense	proximal	-2	no	37.282	36.952	EPSD	COSMIC	33.886	Down-regulation
CMGC_MAPK_p38_MAPK11_ST	P30305	CDC25B	Q15759	MAPK11	S375	R372C	372	Missense	distal	-3	no	37.282	37.915	EPSD	COSMIC	33.886	Up-regulation
CMGC_MAPK_p38_MAPK11_ST	P30305	CDC25B	Q15759	MAPK11	S375	V370I	370	Missense	distal	-5	no	37.282	37.285	EPSD	COSMIC;GDSC;CCLE	33.886	Up-regulation
CMGC_MAPK_p38_MAPK11_ST	P30305	CDC25B	Q15759	MAPK11	S375	E380K	380	Missense	distal	5	no	37.282	37.181	EPSD	COSMIC	33.886	Down-regulation
CMGC_MAPK_p38_MAPK11_ST	P30305	CDC25B	Q15759	MAPK11	S416	A422T	422	Missense	distal	6	no	34.071	34.038	EPSD	COSMIC	33.886	Down-regulation
CMGC_MAPK_p38_MAPK11_ST	P30305	CDC25B	Q15759	MAPK11	S416	A422V	422	Missense	distal	6	no	34.071	34.108	EPSD	COSMIC	33.886	Up-regulation
CMGC_MAPK_p38_MAPK11_ST	P30305	CDC25B	Q15759	MAPK11	S416	Q410K	410	Missense	distal	-6	no	34.071	34.158	EPSD	COSMIC	33.886	Up-regulation
CMGC_MAPK_p38_MAPK11_ST	P30305	CDC25B	Q15759	MAPK11	S416	P417Q	417	Missense	proximal	1	no	34.071	1.928	EPSD	COSMIC	33.886	Loss
CMGC_MAPK_p38_MAPK11_ST	P30305	CDC25B	Q15759	MAPK11	S416	L423F	423	Missense	distal	7	no	34.071	33.873	EPSD	COSMIC	33.886	Loss
CMGC_MAPK_p38_MAPK11_ST	P30305	CDC25B	Q15759	MAPK11	S470	E464G	464	Missense	distal	-6	no	41.932	41.866	EPSD	COSMIC	33.886	Down-regulation
CMGC_MAPK_p38_MAPK11_ST	P30305	CDC25B	Q15759	MAPK11	S470	E464K	464	Missense	distal	-6	no	41.932	41.972	EPSD	COSMIC	33.886	Up-regulation
CMGC_MAPK_p38_MAPK11_ST	P30305	CDC25B	Q15759	MAPK11	S470	L477P	477	Missense	distal	7	no	41.932	42.413	EPSD	COSMIC	33.886	Up-regulation
CMGC_MAPK_p38_MAPK11_ST	P30305	CDC25B	Q15759	MAPK11	S470	A473V	473	Missense	distal	3	no	41.932	41.414	EPSD	COSMIC	33.886	Down-regulation
CMGC_MAPK_p38_MAPK11_ST	P30305	CDC25B	Q15759	MAPK11	S470	A463T	463	Missense	distal	-7	no	41.932	42.077	EPSD	COSMIC	33.886	Up-regulation
CMGC_MAPK_p38_MAPK11_ST	P30305	CDC25B	Q15759	MAPK11	S470	K469R	469	Missense	proximal	-1	no	41.932	41.819	EPSD	COSMIC	33.886	Down-regulation
CMGC_MAPK_p38_MAPK11_ST	P30305	CDC25B	Q15759	MAPK11	S476	K479N	479	Missense	distal	3	no	38.233	37.510	EPSD	COSMIC	33.886	Down-regulation
CMGC_MAPK_p38_MAPK11_ST	P30305	CDC25B	Q15759	MAPK11	S476	L477P	477	Missense	proximal	1	no	38.233	48.051	EPSD	COSMIC	33.886	Up-regulation
CMGC_MAPK_p38_MAPK11_ST	P30305	CDC25B	Q15759	MAPK11	S476	A473V	473	Missense	distal	-3	no	38.233	38.866	EPSD	COSMIC	33.886	Up-regulation
CMGC_MAPK_p38_MAPK11_ST	P30305	CDC25B	Q15759	MAPK11	S476	K469R	469	Missense	distal	-7	no	38.233	38.155	EPSD	COSMIC	33.886	Down-regulation
CMGC_MAPK_p38_MAPK11_ST	P30305	CDC25B	Q15759	MAPK11	S476	R480Q	480	Missense	distal	4	no	38.233	38.202	EPSD	COSMIC	33.886	Down-regulation
CMGC_MAPK_p38_MAPK11_ST	P41235	HNF4A	Q15759	MAPK11	S147	R140Q	140	Missense	distal	-7	no	37.117	37.003	EPSD	COSMIC;GDSC;CCLE	33.886	Down-regulation
CMGC_MAPK_p38_MAPK11_ST	P41235	HNF4A	Q15759	MAPK11	S147	S148F	148	Missense	proximal	1	no	37.117	5.183	EPSD	COSMIC	33.886	Loss
CMGC_MAPK_p38_MAPK11_ST	P41235	HNF4A	Q15759	MAPK11	S147	R141G	141	Missense	distal	-6	no	37.117	37.053	EPSD	COSMIC	33.886	Down-regulation
CMGC_MAPK_p38_MAPK11_ST	P41235	HNF4A	Q15759	MAPK11	S147	R141Q	141	Missense	distal	-6	no	37.117	37.072	EPSD	COSMIC	33.886	Down-regulation
CMGC_MAPK_p38_MAPK11_ST	P41235	HNF4A	Q15759	MAPK11	S167	Q164H	164	Missense	distal	-3	no	47.102	47.614	PhosphoSitePlus	COSMIC	33.886	Up-regulation
CMGC_MAPK_p38_MAPK11_ST	P41235	HNF4A	Q15759	MAPK11	S167	G171R	171	Missense	distal	4	no	47.102	46.596	PhosphoSitePlus	COSMIC	33.886	Down-regulation
CMGC_MAPK_p38_MAPK11_ST	P41235	HNF4A	Q15759	MAPK11	S167	P168T	168	Missense	proximal	1	no	47.102	22.517	PhosphoSitePlus	COSMIC	33.886	Loss
CMGC_MAPK_p38_MAPK11_ST	P41235	HNF4A	Q15759	MAPK11	S167	S170F	170	Missense	distal	3	no	47.102	45.931	PhosphoSitePlus	COSMIC	33.886	Down-regulation
CMGC_MAPK_p38_MAPK11_ST	P41235	HNF4A	Q15759	MAPK11	S167	R163G	163	Missense	distal	-4	no	47.102	45.856	PhosphoSitePlus	COSMIC	33.886	Down-regulation
CMGC_MAPK_p38_MAPK11_ST	P41235	HNF4A	Q15759	MAPK11	S167	R163Q	163	Missense	distal	-4	no	47.102	45.303	PhosphoSitePlus	COSMIC	33.886	Down-regulation
CMGC_MAPK_p38_MAPK11_ST	P41235	HNF4A	Q15759	MAPK11	S167	G174D	174	Missense	distal	7	no	47.102	47.156	PhosphoSitePlus	COSMIC	33.886	Up-regulation
CMGC_MAPK_p38_MAPK11_ST	P41235	HNF4A	Q15759	MAPK11	S318	L319P	319	Missense	proximal	1	no	29.556	39.374	EPSD	COSMIC	33.886	Gain
CMGC_MAPK_p38_MAPK11_ST	P41235	HNF4A	Q15759	MAPK11	S378	M373V	373	Missense	distal	-5	no	41.933	41.722	EPSD	COSMIC	33.886	Down-regulation
CMGC_MAPK_p38_MAPK11_ST	P41235	HNF4A	Q15759	MAPK11	S378	H384Y	384	Missense	distal	6	no	41.933	41.900	EPSD	COSMIC	33.886	Down-regulation
CMGC_MAPK_p38_MAPK11_ST	P41235	HNF4A	Q15759	MAPK11	S378	E372K	372	Missense	distal	-6	no	41.933	41.974	EPSD	COSMIC	33.886	Up-regulation
CMGC_MAPK_p38_MAPK11_ST	P41235	HNF4A	Q15759	MAPK11	T429	A427D	427	Missense	proximal	-2	no	35.953	35.857	EPSD	COSMIC	33.886	Down-regulation
CMGC_MAPK_p38_MAPK11_ST	P41235	HNF4A	Q15759	MAPK11	T429	P433T	433	Missense	distal	4	no	35.953	36.006	EPSD	COSMIC	33.886	Up-regulation
CMGC_MAPK_p38_MAPK11_ST	P41235	HNF4A	Q15759	MAPK11	T429	G425E	425	Missense	distal	-4	no	35.953	35.985	EPSD	COSMIC	33.886	Up-regulation
CMGC_MAPK_p38_MAPK11_ST	P41235	HNF4A	Q15759	MAPK11	T429	P430S	430	Missense	proximal	1	no	35.953	20.454	EPSD	COSMIC	33.886	Loss
CMGC_MAPK_p38_MAPK11_ST	P41235	HNF4A	Q15759	MAPK11	T429	A427T	427	Missense	proximal	-2	no	35.953	36.419	EPSD	COSMIC	33.886	Up-regulation
CMGC_MAPK_p38_MAPK11_ST	P41235	HNF4A	Q15759	MAPK11	T429	T429I	429	Missense	central	0	yes	35.953	0.000	EPSD	COSMIC	33.886	Loss
CMGC_MAPK_p38_MAPK11_ST	P41235	HNF4A	Q15759	MAPK11	T429	P423T	423	Missense	distal	-6	no	35.953	35.937	EPSD	COSMIC	33.886	Down-regulation
CMGC_MAPK_p38_MAPK11_ST	P41235	HNF4A	Q15759	MAPK11	T432	A427D	427	Missense	distal	-5	no	43.031	42.911	EPSD	COSMIC	33.886	Down-regulation
CMGC_MAPK_p38_MAPK11_ST	P41235	HNF4A	Q15759	MAPK11	T432	P433T	433	Missense	proximal	1	no	43.031	18.446	EPSD	COSMIC	33.886	Loss
CMGC_MAPK_p38_MAPK11_ST	P41235	HNF4A	Q15759	MAPK11	T432	G425E	425	Missense	distal	-7	no	43.031	43.069	EPSD	COSMIC	33.886	Up-regulation
CMGC_MAPK_p38_MAPK11_ST	P41235	HNF4A	Q15759	MAPK11	T432	P430S	430	Missense	proximal	-2	no	43.031	42.969	EPSD	COSMIC	33.886	Down-regulation
CMGC_MAPK_p38_MAPK11_ST	P41235	HNF4A	Q15759	MAPK11	T432	P437S	437	Missense	distal	5	no	43.031	42.657	EPSD	COSMIC	33.886	Down-regulation
CMGC_MAPK_p38_MAPK11_ST	P41235	HNF4A	Q15759	MAPK11	T432	A427T	427	Missense	distal	-5	no	43.031	43.035	EPSD	COSMIC	33.886	Up-regulation
CMGC_MAPK_p38_MAPK11_ST	P41235	HNF4A	Q15759	MAPK11	T432	T429I	429	Missense	distal	-3	no	43.031	44.135	EPSD	COSMIC	33.886	Up-regulation
CMGC_MAPK_p38_MAPK11_ST	P41235	HNF4A	Q15759	MAPK11	T432	G439C	439	Missense	distal	7	no	43.031	42.062	EPSD	COSMIC	33.886	Down-regulation
CMGC_MAPK_p38_MAPK11_ST	P41235	HNF4A	Q15759	MAPK11	T432	P437T	437	Missense	distal	5	no	43.031	43.058	EPSD	COSMIC	33.886	Up-regulation
CMGC_MAPK_p38_MAPK11_ST	P41235	HNF4A	Q15759	MAPK11	S436	P433T	433	Missense	distal	-3	no	35.117	35.306	EPSD	COSMIC	33.886	Up-regulation
CMGC_MAPK_p38_MAPK11_ST	P41235	HNF4A	Q15759	MAPK11	S436	P430S	430	Missense	distal	-6	no	35.117	35.212	EPSD	COSMIC	33.886	Up-regulation
CMGC_MAPK_p38_MAPK11_ST	P41235	HNF4A	Q15759	MAPK11	S436	P437S	437	Missense	proximal	1	no	35.117	19.618	EPSD	COSMIC	33.886	Loss
CMGC_MAPK_p38_MAPK11_ST	P41235	HNF4A	Q15759	MAPK11	S436	T429I	429	Missense	distal	-7	no	35.117	34.843	EPSD	COSMIC	33.886	Down-regulation
CMGC_MAPK_p38_MAPK11_ST	P41235	HNF4A	Q15759	MAPK11	S436	G439C	439	Missense	distal	3	no	35.117	33.280	EPSD	COSMIC	33.886	Loss
CMGC_MAPK_p38_MAPK11_ST	P41235	HNF4A	Q15759	MAPK11	S436	P437T	437	Missense	proximal	1	no	35.117	10.532	EPSD	COSMIC	33.886	Loss
CMGC_MAPK_p38_MAPK11_ST	P17544	ATF7	Q15759	MAPK11	S108	M107V	107	Missense	proximal	-1	no	33.895	33.414	EPSD	COSMIC	33.886	Loss
CMGC_MAPK_p38_MAPK11_ST	P17544	ATF7	Q15759	MAPK11	S108	M107R	107	Missense	proximal	-1	no	33.895	34.045	EPSD	COSMIC	33.886	Up-regulation
CMGC_MAPK_p38_MAPK11_ST	P17544	ATF7	Q15759	MAPK11	S108	L109V	109	Missense	proximal	1	no	33.895	3.345	EPSD	COSMIC	33.886	Loss
CMGC_MAPK_p38_MAPK11_ST	P17544	ATF7	Q15759	MAPK11	S108	S111F	111	Missense	distal	3	no	33.895	32.724	EPSD	COSMIC	33.886	Loss
CMGC_MAPK_p38_MAPK11_ST	P17544	ATF7	Q15759	MAPK11	T112	M107V	107	Missense	distal	-5	no	44.708	44.496	EPSD	COSMIC	33.886	Down-regulation
CMGC_MAPK_p38_MAPK11_ST	P17544	ATF7	Q15759	MAPK11	T112	M107R	107	Missense	distal	-5	no	44.708	44.676	EPSD	COSMIC	33.886	Down-regulation
CMGC_MAPK_p38_MAPK11_ST	P17544	ATF7	Q15759	MAPK11	T112	L109V	109	Missense	distal	-3	no	44.708	45.194	EPSD	COSMIC	33.886	Up-regulation
CMGC_MAPK_p38_MAPK11_ST	P17544	ATF7	Q15759	MAPK11	T112	S111F	111	Missense	proximal	-1	no	44.708	43.840	EPSD	COSMIC	33.886	Down-regulation
CMGC_MAPK_p38_MAPK11_ST	P17544	ATF7	Q15759	MAPK11	S128	S128F	128	Missense	central	0	yes	37.974	0.000	EPSD	COSMIC	33.886	Loss
CMGC_MAPK_p38_MAPK11_ST	P17544	ATF7	Q15759	MAPK11	S128	D131H	131	Missense	distal	3	no	37.974	37.264	EPSD	COSMIC	33.886	Down-regulation
CMGC_MAPK_p38_MAPK11_ST	P17544	ATF7	Q15759	MAPK11	S128	P133A	133	Missense	distal	5	no	37.974	37.611	EPSD	COSMIC	33.886	Down-regulation
CMGC_MAPK_p38_MAPK11_ST	P17544	ATF7	Q15759	MAPK11	S132	S128F	128	Missense	distal	-4	no	36.141	33.650	EPSD	COSMIC	33.886	Loss
CMGC_MAPK_p38_MAPK11_ST	P17544	ATF7	Q15759	MAPK11	S132	D131H	131	Missense	proximal	-1	no	36.141	35.423	EPSD	COSMIC	33.886	Down-regulation
CMGC_MAPK_p38_MAPK11_ST	P17544	ATF7	Q15759	MAPK11	S132	S139F	139	Missense	distal	7	no	36.141	35.121	EPSD	COSMIC	33.886	Down-regulation
CMGC_MAPK_p38_MAPK11_ST	P17544	ATF7	Q15759	MAPK11	S132	P133A	133	Missense	proximal	1	no	36.141	27.105	EPSD	COSMIC	33.886	Loss
CMGC_MAPK_p38_MAPK11_ST	P17544	ATF7	Q15759	MAPK11	S136	D131H	131	Missense	distal	-5	no	42.677	42.588	EPSD	COSMIC	33.886	Down-regulation
CMGC_MAPK_p38_MAPK11_ST	P17544	ATF7	Q15759	MAPK11	S136	S139F	139	Missense	distal	3	no	42.677	41.507	EPSD	COSMIC	33.886	Down-regulation
CMGC_MAPK_p38_MAPK11_ST	P17544	ATF7	Q15759	MAPK11	S136	P133A	133	Missense	distal	-3	no	42.677	42.948	EPSD	COSMIC	33.886	Up-regulation
CMGC_MAPK_p38_MAPK11_ST	P17544	ATF7	Q15759	MAPK11	S139	S139F	139	Missense	central	0	yes	40.831	0.000	EPSD	COSMIC	33.886	Loss
CMGC_MAPK_p38_MAPK11_ST	P17544	ATF7	Q15759	MAPK11	S139	K145N	145	Missense	distal	6	no	40.831	40.876	EPSD	COSMIC	33.886	Up-regulation
CMGC_MAPK_p38_MAPK11_ST	P17544	ATF7	Q15759	MAPK11	S139	K145M	145	Missense	distal	6	no	40.831	40.848	EPSD	COSMIC	33.886	Up-regulation
CMGC_MAPK_p38_MAPK11_ST	P17544	ATF7	Q15759	MAPK11	S139	P133A	133	Missense	distal	-6	no	40.831	40.787	EPSD	COSMIC	33.886	Down-regulation
CMGC_MAPK_p38_MAPK11_ST	P17544	ATF7	Q15759	MAPK11	T148	K145N	145	Missense	distal	-3	no	51.979	52.689	EPSD	COSMIC	33.886	Up-regulation
CMGC_MAPK_p38_MAPK11_ST	P17544	ATF7	Q15759	MAPK11	T148	K145M	145	Missense	distal	-3	no	51.979	51.994	EPSD	COSMIC	33.886	Up-regulation
CMGC_MAPK_p38_MAPK11_ST	P17544	ATF7	Q15759	MAPK11	T148	V147A	147	Missense	proximal	-1	no	51.979	52.721	EPSD	COSMIC	33.886	Up-regulation
CMGC_MAPK_p38_MAPK11_ST	P17544	ATF7	Q15759	MAPK11	T156	R163H	163	Missense	distal	7	no	38.937	38.806	EPSD	COSMIC	33.886	Down-regulation
CMGC_MAPK_p38_MAPK11_ST	P17544	ATF7	Q15759	MAPK11	T156	R163C	163	Missense	distal	7	no	38.937	37.961	EPSD	COSMIC	33.886	Down-regulation
CMGC_MAPK_p38_MAPK11_ST	P17544	ATF7	Q15759	MAPK11	T158	R163H	163	Missense	distal	5	no	43.279	43.518	EPSD	COSMIC	33.886	Up-regulation
CMGC_MAPK_p38_MAPK11_ST	P17544	ATF7	Q15759	MAPK11	T158	R163C	163	Missense	distal	5	no	43.279	43.405	EPSD	COSMIC	33.886	Up-regulation
CMGC_MAPK_p38_MAPK11_ST	P17544	ATF7	Q15759	MAPK11	S203	V207D	207	Missense	distal	4	no	32.501	34.144	EPSD	COSMIC	33.886	Gain
CMGC_MAPK_p38_MAPK11_ST	P17544	ATF7	Q15759	MAPK11	S257	I263L	263	Missense	distal	6	no	44.201	44.139	EPSD	COSMIC	33.886	Down-regulation
CMGC_MAPK_p38_MAPK11_ST	P17544	ATF7	Q15759	MAPK11	S315	S322L	322	Missense	distal	7	no	35.327	34.505	EPSD	COSMIC	33.886	Down-regulation
CMGC_MAPK_p38_MAPK11_ST	P17544	ATF7	Q15759	MAPK11	S315	P316S	316	Missense	proximal	1	no	35.327	19.829	EPSD	COSMIC	33.886	Loss
CMGC_MAPK_p38_MAPK11_ST	P17544	ATF7	Q15759	MAPK11	S315	H310P	310	Missense	distal	-5	no	35.327	35.461	EPSD	COSMIC;GDSC	33.886	Up-regulation
CMGC_MAPK_p38_MAPK11_ST	P17544	ATF7	Q15759	MAPK11	S322	S322L	322	Missense	central	0	yes	41.778	0.000	EPSD	COSMIC	33.886	Loss
CMGC_MAPK_p38_MAPK11_ST	P17544	ATF7	Q15759	MAPK11	S322	P316S	316	Missense	distal	-6	no	41.778	41.873	EPSD	COSMIC	33.886	Up-regulation
CMGC_MAPK_p38_MAPK11_ST	P17544	ATF7	Q15759	MAPK11	S322	P326L	326	Missense	distal	4	no	41.778	40.555	EPSD	COSMIC	33.886	Down-regulation
CMGC_MAPK_p38_MAPK11_ST	P17544	ATF7	Q15759	MAPK11	T327	S322L	322	Missense	distal	-5	no	44.232	43.934	EPSD	COSMIC	33.886	Down-regulation
CMGC_MAPK_p38_MAPK11_ST	P17544	ATF7	Q15759	MAPK11	T327	P326L	326	Missense	proximal	-1	no	44.232	43.878	EPSD	COSMIC	33.886	Down-regulation
CMGC_MAPK_p38_MAPK11_ST	P17544	ATF7	Q15759	MAPK11	S434	P435S	435	Missense	proximal	1	no	36.764	21.265	EPSD	COSMIC	33.886	Loss
CMGC_MAPK_p38_MAPK11_ST	P13807	GYS1	Q15759	MAPK11	S645	A640T	640	Missense	distal	-5	no	49.264	49.269	EPSD;PhosphoSitePlus	COSMIC	33.886	Up-regulation
CMGC_MAPK_p38_MAPK11_ST	P13807	GYS1	Q15759	MAPK11	S645	P646S	646	Missense	proximal	1	no	49.264	33.765	EPSD;PhosphoSitePlus	COSMIC;CCLE	33.886	Loss
CMGC_MAPK_p38_MAPK11_ST	P13807	GYS1	Q15759	MAPK11	S647	A640T	640	Missense	distal	-7	no	35.853	35.998	EPSD	COSMIC	33.886	Up-regulation
CMGC_MAPK_p38_MAPK11_ST	P13807	GYS1	Q15759	MAPK11	S647	S653C	653	Missense	distal	6	no	35.853	35.952	EPSD	COSMIC	33.886	Up-regulation
CMGC_MAPK_p38_MAPK11_ST	P13807	GYS1	Q15759	MAPK11	S647	P646S	646	Missense	proximal	-1	no	35.853	35.798	EPSD	COSMIC;CCLE	33.886	Down-regulation
CMGC_MAPK_p38_MAPK11_ST	P13807	GYS1	Q15759	MAPK11	S647	P654L	654	Missense	distal	7	no	35.853	35.372	EPSD	COSMIC;CCLE	33.886	Down-regulation
CMGC_MAPK_p38_MAPK11_ST	P13807	GYS1	Q15759	MAPK11	S653	S653C	653	Missense	central	0	yes	47.120	0.000	EPSD;PhosphoSitePlus	COSMIC	33.886	Loss
CMGC_MAPK_p38_MAPK11_ST	P13807	GYS1	Q15759	MAPK11	S653	P646S	646	Missense	distal	-7	no	47.120	47.259	EPSD;PhosphoSitePlus	COSMIC;CCLE	33.886	Up-regulation
CMGC_MAPK_p38_MAPK11_ST	P13807	GYS1	Q15759	MAPK11	S653	P654L	654	Missense	proximal	1	no	47.120	37.302	EPSD;PhosphoSitePlus	COSMIC;CCLE	33.886	Down-regulation
CMGC_MAPK_p38_MAPK11_ST	P13807	GYS1	Q15759	MAPK11	T713	T713M	713	Missense	central	0	yes	41.768	0.000	EPSD	COSMIC;CCLE	33.886	Loss
CMGC_MAPK_p38_MAPK11_ST	P13807	GYS1	Q15759	MAPK11	T715	T713M	713	Missense	proximal	-2	no	37.151	36.453	EPSD	COSMIC;CCLE	33.886	Down-regulation
CMGC_MAPK_p38_MAPK11_ST	P13807	GYS1	Q15759	MAPK11	S717	T713M	713	Missense	distal	-4	no	35.331	32.814	EPSD	COSMIC;CCLE	33.886	Loss
CMGC_MAPK_p38_MAPK11_ST	P13807	GYS1	Q15759	MAPK11	S718	T713M	713	Missense	distal	-5	no	38.533	38.433	EPSD	COSMIC;CCLE	33.886	Down-regulation
CMGC_MAPK_p38_MAPK11_ST	P13807	GYS1	Q15759	MAPK11	S727	E734K	734	Missense	distal	7	no	56.521	56.555	PhosphoSitePlus;EPSD	COSMIC	33.886	Up-regulation
CMGC_MAPK_p38_MAPK11_ST	P13807	GYS1	Q15759	MAPK11	T729	E735Q	735	Missense	distal	6	no	37.500	37.543	EPSD	COSMIC	33.886	Up-regulation
CMGC_MAPK_p38_MAPK11_ST	P13807	GYS1	Q15759	MAPK11	T729	E734K	734	Missense	distal	5	no	37.500	37.400	EPSD	COSMIC	33.886	Down-regulation
CMGC_MAPK_p38_MAPK11_ST	P13807	GYS1	Q15759	MAPK11	S731	E735Q	735	Missense	distal	4	no	40.841	40.135	EPSD	COSMIC	33.886	Down-regulation
CMGC_MAPK_p38_MAPK11_ST	P13807	GYS1	Q15759	MAPK11	S731	E734K	734	Missense	distal	3	no	40.841	41.423	EPSD	COSMIC	33.886	Up-regulation
CMGC_MAPK_p38_MAPK11_ST	Q02156	PRKCE	Q15759	MAPK11	T228	V232G	232	Missense	distal	4	no	33.020	35.142	EPSD	COSMIC	33.886	Gain
CMGC_MAPK_p38_MAPK11_ST	Q02156	PRKCE	Q15759	MAPK11	T309	N315D	315	Missense	distal	6	no	43.170	43.158	EPSD	COSMIC	33.886	Down-regulation
CMGC_MAPK_p38_MAPK11_ST	Q02156	PRKCE	Q15759	MAPK11	S329	P330S	330	Missense	proximal	1	no	42.861	27.362	EPSD	COSMIC	33.886	Loss
CMGC_MAPK_p38_MAPK11_ST	Q02156	PRKCE	Q15759	MAPK11	S337	P330S	330	Missense	distal	-7	no	34.854	34.993	EPSD	COSMIC	33.886	Up-regulation
CMGC_MAPK_p38_MAPK11_ST	Q02156	PRKCE	Q15759	MAPK11	S381	A378T	378	Missense	distal	-3	no	48.729	48.647	EPSD	COSMIC	33.886	Down-regulation
CMGC_MAPK_p38_MAPK11_ST	Q02156	PRKCE	Q15759	MAPK11	S388	P389T	389	Missense	proximal	1	no	39.349	14.764	EPSD	COSMIC	33.886	Loss
CMGC_MAPK_p38_MAPK11_ST	Q01844	EWSR1	Q15759	MAPK11	T79	T81S	81	Missense	proximal	2	no	48.696	48.501	PhosphoSitePlus	COSMIC	33.886	Down-regulation
CMGC_MAPK_p38_MAPK11_ST	Q01844	EWSR1	Q15759	MAPK11	T79	T75A	75	Missense	distal	-4	no	48.696	47.294	PhosphoSitePlus	COSMIC	33.886	Down-regulation
CMGC_MAPK_p38_MAPK11_ST	Q01844	EWSR1	Q15759	MAPK11	T79	P83H	83	Missense	distal	4	no	48.696	47.439	PhosphoSitePlus	COSMIC	33.886	Down-regulation
CMGC_MAPK_p38_MAPK11_ST	Q01844	EWSR1	Q15759	MAPK11	T79	T78I	78	Missense	proximal	-1	no	48.696	47.179	PhosphoSitePlus	COSMIC	33.886	Down-regulation
CMGC_MAPK_p38_MAPK11_ST	Q01844	EWSR1	Q15759	MAPK11	S259	S255C	255	Missense	distal	-4	no	34.104	30.503	EPSD	COSMIC	33.886	Loss
CMGC_MAPK_p38_MAPK11_ST	Q01844	EWSR1	Q15759	MAPK11	S259	Y254F	254	Missense	distal	-5	no	34.104	33.990	EPSD	COSMIC	33.886	Down-regulation
CMGC_MAPK_p38_MAPK11_ST	Q01844	EWSR1	Q15759	MAPK11	S259	S266L	266	Missense	distal	7	no	34.104	33.282	EPSD	COSMIC	33.886	Loss
CMGC_MAPK_p38_MAPK11_ST	Q01844	EWSR1	Q15759	MAPK11	S259	S259N	259	Missense	central	0	yes	34.104	0.000	EPSD	COSMIC	33.886	Loss
CMGC_MAPK_p38_MAPK11_ST	Q01844	EWSR1	Q15759	MAPK11	S259	S265N	265	Missense	distal	6	no	34.104	34.150	EPSD	COSMIC	33.886	Up-regulation
CMGC_MAPK_p38_MAPK11_ST	Q01844	EWSR1	Q15759	MAPK11	S259	S260N	260	Missense	proximal	1	no	34.104	8.173	EPSD	COSMIC;CCLE	33.886	Loss
CMGC_MAPK_p38_MAPK11_ST	P30281	CCND3	Q15759	MAPK11	S133	P134A	134	Missense	proximal	1	no	42.758	33.722	EPSD	COSMIC	33.886	Loss
CMGC_MAPK_p38_MAPK11_ST	P30281	CCND3	Q15759	MAPK11	S133	A131V	131	Missense	proximal	-2	no	42.758	42.605	EPSD	COSMIC	33.886	Down-regulation
CMGC_MAPK_p38_MAPK11_ST	P30281	CCND3	Q15759	MAPK11	S133	L137V	137	Missense	distal	4	no	42.758	41.988	EPSD	COSMIC	33.886	Down-regulation
CMGC_MAPK_p38_MAPK11_ST	P30281	CCND3	Q15759	MAPK11	S133	S133L	133	Missense	central	0	yes	42.758	0.000	EPSD	COSMIC	33.886	Loss
CMGC_MAPK_p38_MAPK11_ST	P30281	CCND3	Q15759	MAPK11	S264	K268E	268	Missense	distal	4	no	37.891	37.694	EPSD	COSMIC	33.886	Down-regulation
CMGC_MAPK_p38_MAPK11_ST	P30281	CCND3	Q15759	MAPK11	S264	P267L	267	Missense	distal	3	no	37.891	36.933	EPSD	COSMIC	33.886	Down-regulation
CMGC_MAPK_p38_MAPK11_ST	P30281	CCND3	Q15759	MAPK11	T281	P284S	284	Missense	distal	3	no	34.875	35.338	EPSD	COSMIC;CCLE	33.886	Up-regulation
CMGC_MAPK_p38_MAPK11_ST	P30281	CCND3	Q15759	MAPK11	T281	P284L	284	Missense	distal	3	no	34.875	33.917	EPSD	COSMIC;CCLE	33.886	Down-regulation
CMGC_MAPK_p38_MAPK11_ST	P30281	CCND3	Q15759	MAPK11	T281	T283I	283	Missense	proximal	2	no	34.875	31.712	EPSD	COSMIC;GDSC;CCLE	33.886	Loss
CMGC_MAPK_p38_MAPK11_ST	P30281	CCND3	Q15759	MAPK11	T281	V287G	287	Missense	distal	6	no	34.875	34.851	EPSD	COSMIC	33.886	Down-regulation
CMGC_MAPK_p38_MAPK11_ST	P30281	CCND3	Q15759	MAPK11	T281	P284R	284	Missense	distal	3	no	34.875	34.559	EPSD	COSMIC	33.886	Down-regulation
CMGC_MAPK_p38_MAPK11_ST	P30281	CCND3	Q15759	MAPK11	T281	D286G	286	Missense	distal	5	no	34.875	34.845	EPSD	COSMIC	33.886	Down-regulation
CMGC_MAPK_p38_MAPK11_ST	P30281	CCND3	Q15759	MAPK11	T281	V287D	287	Missense	distal	6	no	34.875	34.852	EPSD	COSMIC;CCLE	33.886	Down-regulation
CMGC_MAPK_p38_MAPK11_ST	P30281	CCND3	Q15759	MAPK11	T281	P284T	284	Missense	distal	3	no	34.875	35.120	EPSD	COSMIC	33.886	Up-regulation
CMGC_MAPK_p38_MAPK11_ST	P30281	CCND3	Q15759	MAPK11	T281	G277W	277	Missense	distal	-4	no	34.875	34.353	EPSD	COSMIC	33.886	Down-regulation
CMGC_MAPK_p38_MAPK11_ST	P30281	CCND3	Q15759	MAPK11	T283	P284S	284	Missense	proximal	1	no	51.057	35.559	PhosphoSitePlus	COSMIC;CCLE	33.886	Down-regulation
CMGC_MAPK_p38_MAPK11_ST	P30281	CCND3	Q15759	MAPK11	T283	P284L	284	Missense	proximal	1	no	51.057	41.240	PhosphoSitePlus	COSMIC;CCLE	33.886	Down-regulation
CMGC_MAPK_p38_MAPK11_ST	P30281	CCND3	Q15759	MAPK11	T283	I290R	290	Missense	distal	7	no	51.057	51.746	PhosphoSitePlus	COSMIC;CCLE	33.886	Up-regulation
CMGC_MAPK_p38_MAPK11_ST	P30281	CCND3	Q15759	MAPK11	T283	T283I	283	Missense	central	0	yes	51.057	0.000	PhosphoSitePlus	COSMIC;GDSC;CCLE	33.886	Loss
CMGC_MAPK_p38_MAPK11_ST	P30281	CCND3	Q15759	MAPK11	T283	V287G	287	Missense	distal	4	no	51.057	53.179	PhosphoSitePlus	COSMIC	33.886	Up-regulation
CMGC_MAPK_p38_MAPK11_ST	P30281	CCND3	Q15759	MAPK11	T283	P284R	284	Missense	proximal	1	no	51.057	-9.817	PhosphoSitePlus	COSMIC	33.886	Loss
CMGC_MAPK_p38_MAPK11_ST	P30281	CCND3	Q15759	MAPK11	T283	D286G	286	Missense	distal	3	no	51.057	51.083	PhosphoSitePlus	COSMIC	33.886	Up-regulation
CMGC_MAPK_p38_MAPK11_ST	P30281	CCND3	Q15759	MAPK11	T283	V287D	287	Missense	distal	4	no	51.057	52.700	PhosphoSitePlus	COSMIC;CCLE	33.886	Up-regulation
CMGC_MAPK_p38_MAPK11_ST	P30281	CCND3	Q15759	MAPK11	T283	P284T	284	Missense	proximal	1	no	51.057	26.473	PhosphoSitePlus	COSMIC	33.886	Loss
CMGC_MAPK_p38_MAPK11_ST	P30281	CCND3	Q15759	MAPK11	T283	G277W	277	Missense	distal	-6	no	51.057	51.024	PhosphoSitePlus	COSMIC	33.886	Down-regulation
CMGC_MAPK_p38_MAPK11_ST	P30281	CCND3	Q15759	MAPK11	T283	A289P	289	Missense	distal	6	no	51.057	51.045	PhosphoSitePlus	COSMIC	33.886	Down-regulation
CMGC_MAPK_p38_MAPK11_ST	P30281	CCND3	Q15759	MAPK11	T288	P284S	284	Missense	distal	-4	no	38.653	40.370	EPSD	COSMIC;CCLE	33.886	Up-regulation
CMGC_MAPK_p38_MAPK11_ST	P30281	CCND3	Q15759	MAPK11	T288	P284L	284	Missense	distal	-4	no	38.653	37.082	EPSD	COSMIC;CCLE	33.886	Down-regulation
CMGC_MAPK_p38_MAPK11_ST	P30281	CCND3	Q15759	MAPK11	T288	I290R	290	Missense	proximal	2	no	38.653	40.876	EPSD	COSMIC;CCLE	33.886	Up-regulation
CMGC_MAPK_p38_MAPK11_ST	P30281	CCND3	Q15759	MAPK11	T288	T283I	283	Missense	distal	-5	no	38.653	38.344	EPSD	COSMIC;GDSC;CCLE	33.886	Down-regulation
CMGC_MAPK_p38_MAPK11_ST	P30281	CCND3	Q15759	MAPK11	T288	V287G	287	Missense	proximal	-1	no	38.653	39.399	EPSD	COSMIC	33.886	Up-regulation
CMGC_MAPK_p38_MAPK11_ST	P30281	CCND3	Q15759	MAPK11	T288	P284R	284	Missense	distal	-4	no	38.653	39.613	EPSD	COSMIC	33.886	Up-regulation
CMGC_MAPK_p38_MAPK11_ST	P30281	CCND3	Q15759	MAPK11	T288	D286G	286	Missense	proximal	-2	no	38.653	38.324	EPSD	COSMIC	33.886	Down-regulation
CMGC_MAPK_p38_MAPK11_ST	P30281	CCND3	Q15759	MAPK11	T288	V287D	287	Missense	proximal	-1	no	38.653	39.329	EPSD	COSMIC;CCLE	33.886	Up-regulation
CMGC_MAPK_p38_MAPK11_ST	P30281	CCND3	Q15759	MAPK11	T288	P284T	284	Missense	distal	-4	no	38.653	39.774	EPSD	COSMIC	33.886	Up-regulation
CMGC_MAPK_p38_MAPK11_ST	P30281	CCND3	Q15759	MAPK11	T288	A289P	289	Missense	proximal	1	no	38.653	47.689	EPSD	COSMIC	33.886	Up-regulation
CMGC_MAPK_p38_MAPK11_ST	P04150	NR3C1	Q15759	MAPK11	S45	A49V	49	Missense	distal	4	no	37.002	34.987	EPSD	COSMIC	33.886	Down-regulation
CMGC_MAPK_p38_MAPK11_ST	P04150	NR3C1	Q15759	MAPK11	T145	A146V	146	Missense	proximal	1	no	37.721	6.389	EPSD	COSMIC;GDSC;CCLE	33.886	Loss
CMGC_MAPK_p38_MAPK11_ST	P04150	NR3C1	Q15759	MAPK11	T145	A146S	146	Missense	proximal	1	no	37.721	31.258	EPSD	COSMIC;GDSC;CCLE	33.886	Loss
CMGC_MAPK_p38_MAPK11_ST	P04150	NR3C1	Q15759	MAPK11	T145	S142L	142	Missense	distal	-3	no	37.721	38.282	EPSD	COSMIC	33.886	Up-regulation
CMGC_MAPK_p38_MAPK11_ST	P04150	NR3C1	Q15759	MAPK11	T145	A150S	150	Missense	distal	5	no	37.721	37.711	EPSD	COSMIC	33.886	Down-regulation
CMGC_MAPK_p38_MAPK11_ST	P04150	NR3C1	Q15759	MAPK11	S211	T208A	208	Missense	distal	-3	no	51.399	51.480	EPSD	COSMIC	33.886	Up-regulation
CMGC_MAPK_p38_MAPK11_ST	P04150	NR3C1	Q15759	MAPK11	S267	P268L	268	Missense	proximal	1	no	41.419	31.602	EPSD	COSMIC	33.886	Loss
CMGC_MAPK_p38_MAPK11_ST	P04150	NR3C1	Q15759	MAPK11	T288	E285K	285	Missense	distal	-3	no	39.583	39.618	EPSD	COSMIC	33.886	Up-regulation
CMGC_MAPK_p38_MAPK11_ST	P04150	NR3C1	Q15759	MAPK11	S340	A339S	339	Missense	proximal	-1	no	36.454	36.363	EPSD	COSMIC	33.886	Down-regulation
CMGC_MAPK_p38_MAPK11_ST	P04150	NR3C1	Q15759	MAPK11	S395	Y393H	393	Missense	proximal	-2	no	37.828	37.398	EPSD	COSMIC	33.886	Down-regulation
CMGC_MAPK_p38_MAPK11_ST	P04150	NR3C1	Q15759	MAPK11	S404	P405T	405	Missense	proximal	1	no	37.425	12.840	EPSD	COSMIC	33.886	Loss
TK_EGFR_ERBB4_Y	Q15303	ERBB4	Q15303	ERBB4	Y157	Y157C	157	Missense	central	0	yes	0.000	0.000	EPSD	COSMIC	0.000	Loss
TK_EGFR_ERBB4_Y	Q15303	ERBB4	Q15303	ERBB4	Y875	Y875C	875	Missense	central	0	yes	0.000	0.000	EPSD	COSMIC	0.000	Loss
TK_EGFR_ERBB4_Y	Q15303	ERBB4	Q15303	ERBB4	Y1035	Y1035H	1035	Missense	central	0	yes	0.000	0.000	EPSD	COSMIC;GDSC;CCLE	0.000	Loss
TK_EGFR_ERBB4_Y	Q15303	ERBB4	Q15303	ERBB4	Y1056	Y1056F	1056	Missense	central	0	yes	0.000	0.000	PhosphoSitePlus;EPSD	COSMIC	0.000	Loss
TK_EGFR_ERBB4_Y	Q15303	ERBB4	Q15303	ERBB4	Y1188	Y1188C	1188	Missense	central	0	yes	0.000	0.000	EPSD	COSMIC	0.000	Loss
TK_EGFR_ERBB4_Y	Q15303	ERBB4	Q15303	ERBB4	Y1242	Y1242C	1242	Missense	central	0	yes	0.000	0.000	EPSD	COSMIC;GDSC;CCLE	0.000	Loss
TK_EGFR_ERBB4_Y	Q15303	ERBB4	Q15303	ERBB4	Y1258	Y1258C	1258	Missense	central	0	yes	0.000	0.000	EPSD	COSMIC	0.000	Loss
TK_EGFR_ERBB4_Y	Q15303	ERBB4	Q15303	ERBB4	Y1262	Y1262C	1262	Missense	central	0	yes	0.000	0.000	EPSD	COSMIC	0.000	Loss
TK_EGFR_ERBB4_Y	Q15303	ERBB4	Q15303	ERBB4	Y1266	Y1266H	1266	Missense	central	0	yes	0.000	0.000	EPSD	COSMIC	0.000	Loss
TK_EGFR_ERBB4_Y	Q15303	ERBB4	Q15303	ERBB4	Y1301	Y1301C	1301	Missense	central	0	yes	0.000	0.000	EPSD	COSMIC	0.000	Loss
Other_NKF2_PINK1_ST	Q6NUN9	ZNF746	Q9BXM7	PINK1	T278	K271E	271	Missense	distal	-7	no	12.917	12.870	EPSD	COSMIC	11.649	Down-regulation
Other_NKF2_PINK1_ST	Q6NUN9	ZNF746	Q9BXM7	PINK1	T278	T278M	278	Missense	central	0	yes	12.917	0.000	EPSD	COSMIC	11.649	Loss
Other_NKF2_PINK1_ST	Q6NUN9	ZNF746	Q9BXM7	PINK1	S359	E357D	357	Missense	proximal	-2	no	12.836	11.633	EPSD	COSMIC	11.649	Loss
Other_NKF2_PINK1_ST	Q6NUN9	ZNF746	Q9BXM7	PINK1	S499	G502S	502	Missense	distal	3	no	13.659	15.110	EPSD	COSMIC	11.649	Up-regulation
Other_NKF2_PINK1_ST	Q6NUN9	ZNF746	Q9BXM7	PINK1	S499	G500S	500	Missense	proximal	1	no	13.659	14.464	EPSD	COSMIC	11.649	Up-regulation
Other_NKF2_PINK1_ST	Q6NUN9	ZNF746	Q9BXM7	PINK1	S499	G501S	501	Missense	proximal	2	no	13.659	15.073	EPSD	COSMIC	11.649	Up-regulation
Other_NKF2_PINK1_ST	Q6NUN9	ZNF746	Q9BXM7	PINK1	S613	P619L	619	Missense	distal	6	no	25.266	24.562	EPSD;PhosphoSitePlus	COSMIC	11.649	Down-regulation
Other_NKF2_PINK1_ST	Q6NUN9	ZNF746	Q9BXM7	PINK1	S613	P610S	610	Missense	distal	-3	no	25.266	25.178	EPSD;PhosphoSitePlus	COSMIC	11.649	Down-regulation
Other_NKF2_PINK1_ST	Q6NUN9	ZNF746	Q9BXM7	PINK1	S613	P619R	619	Missense	distal	6	no	25.266	26.837	EPSD;PhosphoSitePlus	COSMIC	11.649	Up-regulation
Other_NKF2_PINK1_ST	O95202	LETM1	Q9BXM7	PINK1	T192	R197K	197	Missense	distal	5	no	25.697	24.495	PhosphoSitePlus	COSMIC	11.649	Down-regulation
Other_NKF2_PINK1_ST	Q9BXM7	PINK1	Q9BXM7	PINK1	T257	S261P	261	Missense	distal	4	no	24.042	24.145	EPSD;PhosphoSitePlus	COSMIC	11.649	Up-regulation
Other_NKF2_PINK1_ST	Q9BXM7	PINK1	Q9BXM7	PINK1	S402	D406N	406	Missense	distal	4	no	24.684	24.298	PhosphoSitePlus;EPSD	COSMIC	11.649	Down-regulation
Other_NKF2_PINK1_ST	O60260	PRKN	Q9BXM7	PINK1	S65	Q71R	71	Missense	distal	6	no	27.647	28.305	PhosphoSitePlus	COSMIC	11.649	Up-regulation
Other_NKF2_PINK1_ST	O60260	PRKN	Q9BXM7	PINK1	S65	C59F	59	Missense	distal	-6	no	27.647	24.813	PhosphoSitePlus	COSMIC	11.649	Down-regulation
Other_NKF2_PINK1_ST	O60260	PRKN	Q9BXM7	PINK1	S65	V67F	67	Missense	proximal	2	no	27.647	27.164	PhosphoSitePlus	COSMIC	11.649	Down-regulation
Other_NKF2_PINK1_ST	O60260	PRKN	Q9BXM7	PINK1	S65	D62H	62	Missense	distal	-3	no	27.647	27.562	PhosphoSitePlus	COSMIC	11.649	Down-regulation
Other_NKF2_PINK1_ST	O60260	PRKN	Q9BXM7	PINK1	S65	V67D	67	Missense	proximal	2	no	27.647	26.432	PhosphoSitePlus	COSMIC	11.649	Down-regulation
Other_NKF2_PINK1_ST	O60260	PRKN	Q9BXM7	PINK1	S65	Q71P	71	Missense	distal	6	no	27.647	26.735	PhosphoSitePlus	COSMIC	11.649	Down-regulation
Other_NKF2_PINK1_ST	O60260	PRKN	Q9BXM7	PINK1	S65	H68Y	68	Missense	distal	3	no	27.647	26.686	PhosphoSitePlus	COSMIC	11.649	Down-regulation
Other_NKF2_PINK1_ST	O60260	PRKN	Q9BXM7	PINK1	S65	H68N	68	Missense	distal	3	no	27.647	27.316	PhosphoSitePlus	COSMIC	11.649	Down-regulation
Other_NKF2_PINK1_ST	O60260	PRKN	Q9BXM7	PINK1	S65	Q63K	63	Missense	proximal	-2	no	27.647	26.925	PhosphoSitePlus	COSMIC	11.649	Down-regulation
Other_NKF2_PINK1_ST	O60260	PRKN	Q9BXM7	PINK1	S65	N58I	58	Missense	distal	-7	no	27.647	27.653	PhosphoSitePlus	COSMIC	11.649	Up-regulation
Other_NKF2_PINK1_ST	O60260	PRKN	Q9BXM7	PINK1	S65	R72K	72	Missense	distal	7	no	27.647	27.597	PhosphoSitePlus	COSMIC	11.649	Down-regulation
Other_NKF2_PINK1_ST	O60260	PRKN	Q9BXM7	PINK1	T83	K76E	76	Missense	distal	-7	no	13.262	13.216	EPSD	COSMIC	11.649	Down-regulation
Other_NKF2_PINK1_ST	O60260	PRKN	Q9BXM7	PINK1	T83	M80I	80	Missense	distal	-3	no	13.262	13.360	EPSD	COSMIC	11.649	Up-regulation
Other_NKF2_PINK1_ST	O60260	PRKN	Q9BXM7	PINK1	T83	D86N	86	Missense	distal	3	no	13.262	13.516	EPSD	COSMIC	11.649	Up-regulation
Other_NKF2_PINK1_ST	O60260	PRKN	Q9BXM7	PINK1	T83	D86E	86	Missense	distal	3	no	13.262	13.899	EPSD	COSMIC	11.649	Up-regulation
Other_NKF2_PINK1_ST	O60260	PRKN	Q9BXM7	PINK1	T83	P88L	88	Missense	distal	5	no	13.262	12.370	EPSD	COSMIC	11.649	Down-regulation
Other_NKF2_PINK1_ST	O60260	PRKN	Q9BXM7	PINK1	T83	R89K	89	Missense	distal	6	no	13.262	12.550	EPSD	COSMIC	11.649	Down-regulation
Other_NKF2_PINK1_ST	O60260	PRKN	Q9BXM7	PINK1	T83	P88R	88	Missense	distal	5	no	13.262	13.463	EPSD	COSMIC	11.649	Up-regulation
Other_NKF2_PINK1_ST	O60260	PRKN	Q9BXM7	PINK1	T83	A82E	82	Missense	proximal	-1	no	13.262	14.055	EPSD	COSMIC	11.649	Up-regulation
Other_NKF2_PINK1_ST	O60260	PRKN	Q9BXM7	PINK1	T83	R89G	89	Missense	distal	6	no	13.262	10.264	EPSD	COSMIC	11.649	Loss
Other_NKF2_PINK1_ST	O60260	PRKN	Q9BXM7	PINK1	T83	D87Y	87	Missense	distal	4	no	13.262	13.491	EPSD	COSMIC	11.649	Up-regulation
Other_NKF2_PINK1_ST	O60260	PRKN	Q9BXM7	PINK1	T83	A82T	82	Missense	proximal	-1	no	13.262	13.456	EPSD	COSMIC	11.649	Up-regulation
Other_NKF2_PINK1_ST	O60260	PRKN	Q9BXM7	PINK1	S378	H373D	373	Missense	distal	-5	no	8.569	12.466	EPSD	COSMIC	11.649	Gain
TKL_RAF_RAF_RAF1_ST	P04049	RAF1	P04049	RAF1	S12	S12C	12	Missense	central	0	yes	9.852	0.000	EPSD	COSMIC	7.934	Loss
TKL_RAF_RAF_RAF1_ST	P04049	RAF1	P04049	RAF1	S12	G14S	14	Missense	proximal	2	no	9.852	10.332	EPSD	COSMIC	7.934	Up-regulation
TKL_RAF_RAF_RAF1_ST	P04049	RAF1	P04049	RAF1	S12	Q5H	5	Missense	distal	-7	no	9.852	10.291	EPSD	COSMIC	7.934	Up-regulation
TKL_RAF_RAF_RAF1_ST	P04049	RAF1	P04049	RAF1	T182	N189K	189	Missense	distal	7	no	7.941	7.742	EPSD	COSMIC	7.934	Loss
TKL_RAF_RAF_RAF1_ST	P04049	RAF1	P04049	RAF1	T182	S188N	188	Missense	distal	6	no	7.941	7.607	EPSD	COSMIC	7.934	Loss
TKL_RAF_RAF_RAF1_ST	P04049	RAF1	P04049	RAF1	T182	H175R	175	Missense	distal	-7	no	7.941	7.758	EPSD	COSMIC	7.934	Loss
TKL_RAF_RAF_RAF1_ST	P04049	RAF1	P04049	RAF1	T182	M183T	183	Missense	proximal	1	no	7.941	8.070	EPSD	COSMIC	7.934	Up-regulation
TKL_RAF_RAF_RAF1_ST	P04049	RAF1	P04049	RAF1	T182	S188R	188	Missense	distal	6	no	7.941	7.733	EPSD	COSMIC	7.934	Loss
TKL_RAF_RAF_RAF1_ST	P04049	RAF1	P04049	RAF1	S204	L209P	209	Missense	distal	5	no	10.128	10.411	EPSD	COSMIC	7.934	Up-regulation
TKL_RAF_RAF_RAF1_ST	P04049	RAF1	P04049	RAF1	S204	A208T	208	Missense	distal	4	no	10.128	10.231	EPSD	COSMIC	7.934	Up-regulation
TKL_RAF_RAF_RAF1_ST	P04049	RAF1	P04049	RAF1	S204	N198D	198	Missense	distal	-6	no	10.128	10.213	EPSD	COSMIC	7.934	Up-regulation
TKL_RAF_RAF_RAF1_ST	P04049	RAF1	P04049	RAF1	S204	S199F	199	Missense	distal	-5	no	10.128	10.027	EPSD	COSMIC	7.934	Down-regulation
TKL_RAF_RAF_RAF1_ST	P04049	RAF1	P04049	RAF1	S204	T200A	200	Missense	distal	-4	no	10.128	11.086	EPSD	COSMIC	7.934	Up-regulation
TKL_RAF_RAF_RAF1_ST	P04049	RAF1	P04049	RAF1	S204	G205R	205	Missense	proximal	1	no	10.128	9.715	EPSD	COSMIC	7.934	Down-regulation
TKL_RAF_RAF_RAF1_ST	P04049	RAF1	P04049	RAF1	S220	M217I	217	Missense	distal	-3	no	8.780	8.636	EPSD	COSMIC	7.934	Down-regulation
TKL_RAF_RAF_RAF1_ST	P04049	RAF1	P04049	RAF1	S257	S259A	259	Missense	proximal	2	no	11.654	12.443	EPSD	COSMIC	7.934	Up-regulation
TKL_RAF_RAF_RAF1_ST	P04049	RAF1	P04049	RAF1	S257	P261L	261	Missense	distal	4	no	11.654	12.804	EPSD	COSMIC	7.934	Up-regulation
TKL_RAF_RAF_RAF1_ST	P04049	RAF1	P04049	RAF1	S257	S259C	259	Missense	proximal	2	no	11.654	11.543	EPSD	COSMIC	7.934	Down-regulation
TKL_RAF_RAF_RAF1_ST	P04049	RAF1	P04049	RAF1	S257	S259P	259	Missense	proximal	2	no	11.654	12.269	EPSD	COSMIC	7.934	Up-regulation
TKL_RAF_RAF_RAF1_ST	P04049	RAF1	P04049	RAF1	S257	T260K	260	Missense	distal	3	no	11.654	11.921	EPSD	COSMIC	7.934	Up-regulation
TKL_RAF_RAF_RAF1_ST	P04049	RAF1	P04049	RAF1	S257	P261T	261	Missense	distal	4	no	11.654	12.604	EPSD	COSMIC	7.934	Up-regulation
TKL_RAF_RAF_RAF1_ST	P04049	RAF1	P04049	RAF1	S257	N262K	262	Missense	distal	5	no	11.654	11.534	EPSD	COSMIC	7.934	Down-regulation
TKL_RAF_RAF_RAF1_ST	P04049	RAF1	P04049	RAF1	S257	T260I	260	Missense	distal	3	no	11.654	12.131	EPSD	COSMIC	7.934	Up-regulation
TKL_RAF_RAF_RAF1_ST	P04049	RAF1	P04049	RAF1	S257	L251V	251	Missense	distal	-6	no	11.654	11.766	EPSD	COSMIC	7.934	Up-regulation
TKL_RAF_RAF_RAF1_ST	P04049	RAF1	P04049	RAF1	S257	P261S	261	Missense	distal	4	no	11.654	13.602	EPSD	COSMIC	7.934	Up-regulation
TKL_RAF_RAF_RAF1_ST	P04049	RAF1	P04049	RAF1	S257	V263A	263	Missense	distal	6	no	11.654	11.611	EPSD	COSMIC	7.934	Down-regulation
TKL_RAF_RAF_RAF1_ST	P04049	RAF1	P04049	RAF1	S257	V263D	263	Missense	distal	6	no	11.654	11.337	EPSD	COSMIC	7.934	Down-regulation
TKL_RAF_RAF_RAF1_ST	P04049	RAF1	P04049	RAF1	S259	S259A	259	Missense	central	0	yes	15.532	0.000	EPSD;PhosphoSitePlus	COSMIC	7.934	Loss
TKL_RAF_RAF_RAF1_ST	P04049	RAF1	P04049	RAF1	S259	P261L	261	Missense	proximal	2	no	15.532	14.979	EPSD;PhosphoSitePlus	COSMIC	7.934	Down-regulation
TKL_RAF_RAF_RAF1_ST	P04049	RAF1	P04049	RAF1	S259	S259C	259	Missense	central	0	yes	15.532	0.000	EPSD;PhosphoSitePlus	COSMIC	7.934	Loss
TKL_RAF_RAF_RAF1_ST	P04049	RAF1	P04049	RAF1	S259	S259P	259	Missense	central	0	yes	15.532	0.000	EPSD;PhosphoSitePlus	COSMIC	7.934	Loss
TKL_RAF_RAF_RAF1_ST	P04049	RAF1	P04049	RAF1	S259	T260K	260	Missense	proximal	1	no	15.532	15.396	EPSD;PhosphoSitePlus	COSMIC	7.934	Down-regulation
TKL_RAF_RAF_RAF1_ST	P04049	RAF1	P04049	RAF1	S259	P261T	261	Missense	proximal	2	no	15.532	14.917	EPSD;PhosphoSitePlus	COSMIC	7.934	Down-regulation
TKL_RAF_RAF_RAF1_ST	P04049	RAF1	P04049	RAF1	S259	N262K	262	Missense	distal	3	no	15.532	14.756	EPSD;PhosphoSitePlus	COSMIC	7.934	Down-regulation
TKL_RAF_RAF_RAF1_ST	P04049	RAF1	P04049	RAF1	S259	T260I	260	Missense	proximal	1	no	15.532	15.631	EPSD;PhosphoSitePlus	COSMIC	7.934	Up-regulation
TKL_RAF_RAF_RAF1_ST	P04049	RAF1	P04049	RAF1	S259	P261S	261	Missense	proximal	2	no	15.532	14.917	EPSD;PhosphoSitePlus	COSMIC	7.934	Down-regulation
TKL_RAF_RAF_RAF1_ST	P04049	RAF1	P04049	RAF1	S259	V263A	263	Missense	distal	4	no	15.532	15.566	EPSD;PhosphoSitePlus	COSMIC	7.934	Up-regulation
TKL_RAF_RAF_RAF1_ST	P04049	RAF1	P04049	RAF1	S259	V263D	263	Missense	distal	4	no	15.532	15.165	EPSD;PhosphoSitePlus	COSMIC	7.934	Down-regulation
TKL_RAF_RAF_RAF1_ST	P04049	RAF1	P04049	RAF1	T268	P261L	261	Missense	distal	-7	no	13.672	13.723	EPSD	COSMIC	7.934	Up-regulation
TKL_RAF_RAF_RAF1_ST	P04049	RAF1	P04049	RAF1	T268	D273Y	273	Missense	distal	5	no	13.672	13.328	EPSD	COSMIC	7.934	Down-regulation
TKL_RAF_RAF_RAF1_ST	P04049	RAF1	P04049	RAF1	T268	P261T	261	Missense	distal	-7	no	13.672	13.757	EPSD	COSMIC	7.934	Up-regulation
TKL_RAF_RAF_RAF1_ST	P04049	RAF1	P04049	RAF1	T268	N262K	262	Missense	distal	-6	no	13.672	13.618	EPSD	COSMIC	7.934	Down-regulation
TKL_RAF_RAF_RAF1_ST	P04049	RAF1	P04049	RAF1	T268	P261S	261	Missense	distal	-7	no	13.672	13.595	EPSD	COSMIC	7.934	Down-regulation
TKL_RAF_RAF_RAF1_ST	P04049	RAF1	P04049	RAF1	T268	V263A	263	Missense	distal	-5	no	13.672	13.604	EPSD	COSMIC	7.934	Down-regulation
TKL_RAF_RAF_RAF1_ST	P04049	RAF1	P04049	RAF1	T268	V263D	263	Missense	distal	-5	no	13.672	13.389	EPSD	COSMIC	7.934	Down-regulation
TKL_RAF_RAF_RAF1_ST	P04049	RAF1	P04049	RAF1	S338	R333C	333	Missense	distal	-5	no	14.086	13.783	EPSD;PhosphoSitePlus	COSMIC	7.934	Down-regulation
TKL_RAF_RAF_RAF1_ST	P04049	RAF1	P04049	RAF1	S338	Q335H	335	Missense	distal	-3	no	14.086	8.074	EPSD;PhosphoSitePlus	COSMIC;GDSC;CCLE	7.934	Down-regulation
TKL_RAF_RAF_RAF1_ST	P04049	RAF1	P04049	RAF1	S604	P600S	600	Missense	distal	-4	no	5.568	8.834	EPSD	COSMIC	7.934	Gain
TKL_RAF_RAF_RAF1_ST	P04049	RAF1	P04049	RAF1	S621	A620D	620	Missense	proximal	-1	no	15.150	15.039	PhosphoSitePlus;EPSD	COSMIC	7.934	Down-regulation
TKL_RAF_RAF_RAF1_ST	P04049	RAF1	P04049	RAF1	S621	R618L	618	Missense	distal	-3	no	15.150	12.564	PhosphoSitePlus;EPSD	COSMIC	7.934	Down-regulation
TKL_RAF_RAF_RAF1_ST	P04049	RAF1	P04049	RAF1	S621	R618Q	618	Missense	distal	-3	no	15.150	13.556	PhosphoSitePlus;EPSD	COSMIC	7.934	Down-regulation
TKL_RAF_RAF_RAF1_ST	Q13118	KLF10	P04049	RAF1	T93	P95H	95	Missense	proximal	2	no	13.824	12.752	PhosphoSitePlus	COSMIC;GDSC;CCLE	7.934	Down-regulation
TKL_RAF_RAF_RAF1_ST	Q13118	KLF10	P04049	RAF1	T93	S99F	99	Missense	distal	6	no	13.824	13.405	PhosphoSitePlus	COSMIC	7.934	Down-regulation
TKL_RAF_RAF_RAF1_ST	Q13118	KLF10	P04049	RAF1	S143	A150D	150	Missense	distal	7	no	8.635	9.045	EPSD	COSMIC	7.934	Up-regulation
TKL_RAF_RAF_RAF1_ST	Q92934	BAD	P04049	RAF1	S57	E53K	53	Missense	distal	-4	no	7.688	8.453	EPSD	COSMIC	7.934	Gain
TKL_RAF_RAF_RAF1_ST	Q92934	BAD	P04049	RAF1	S75	A78E	78	Missense	distal	3	no	17.199	18.353	PhosphoSitePlus;EPSD	COSMIC	7.934	Up-regulation
TKL_RAF_RAF_RAF1_ST	Q92934	BAD	P04049	RAF1	S97	P101S	101	Missense	distal	4	no	6.303	8.251	EPSD	COSMIC	7.934	Gain
TKL_RAF_RAF_RAF1_ST	Q92934	BAD	P04049	RAF1	S99	P102L	102	Missense	distal	3	no	13.786	13.522	EPSD;PhosphoSitePlus	COSMIC	7.934	Down-regulation
TKL_RAF_RAF_RAF1_ST	Q92934	BAD	P04049	RAF1	S99	S97P	97	Missense	proximal	-2	no	13.786	13.692	EPSD;PhosphoSitePlus	COSMIC	7.934	Down-regulation
TKL_RAF_RAF_RAF1_ST	Q92934	BAD	P04049	RAF1	S99	R98H	98	Missense	proximal	-1	no	13.786	13.721	EPSD;PhosphoSitePlus	COSMIC	7.934	Down-regulation
TKL_RAF_RAF_RAF1_ST	Q92934	BAD	P04049	RAF1	S99	P101S	101	Missense	proximal	2	no	13.786	13.171	EPSD;PhosphoSitePlus	COSMIC	7.934	Down-regulation
TKL_RAF_RAF_RAF1_ST	Q92934	BAD	P04049	RAF1	S118	S124F	124	Missense	distal	6	no	14.641	14.222	EPSD;PhosphoSitePlus	COSMIC	7.934	Down-regulation
TKL_RAF_RAF_RAF1_ST	Q92934	BAD	P04049	RAF1	S134	K127N	127	Missense	distal	-7	no	8.211	8.533	EPSD	COSMIC	7.934	Up-regulation
TKL_RAF_RAF_RAF1_ST	Q92934	BAD	P04049	RAF1	S134	K133N	133	Missense	proximal	-1	no	8.211	8.441	EPSD	COSMIC	7.934	Up-regulation
TKL_RAF_RAF_RAF1_ST	Q92934	BAD	P04049	RAF1	S144	W147R	147	Missense	distal	3	no	12.633	13.363	EPSD	COSMIC	7.934	Up-regulation
TKL_RAF_RAF_RAF1_ST	Q92934	BAD	P04049	RAF1	T148	W147R	147	Missense	proximal	-1	no	8.089	8.045	EPSD	COSMIC	7.934	Down-regulation
TKL_RAF_RAF_RAF1_ST	Q02750	MAP2K1	P04049	RAF1	S218	S212N	212	Missense	distal	-6	no	14.805	15.018	EPSD;PhosphoSitePlus	COSMIC	7.934	Up-regulation
TKL_RAF_RAF_RAF1_ST	Q02750	MAP2K1	P04049	RAF1	S218	L215F	215	Missense	distal	-3	no	14.805	13.215	EPSD;PhosphoSitePlus	COSMIC	7.934	Down-regulation
TKL_RAF_RAF_RAF1_ST	Q02750	MAP2K1	P04049	RAF1	S218	G213V	213	Missense	distal	-5	no	14.805	15.042	EPSD;PhosphoSitePlus	COSMIC	7.934	Up-regulation
TKL_RAF_RAF_RAF1_ST	Q02750	MAP2K1	P04049	RAF1	S218	S218F	218	Missense	central	0	yes	14.805	0.000	EPSD;PhosphoSitePlus	COSMIC	7.934	Loss
TKL_RAF_RAF_RAF1_ST	Q02750	MAP2K1	P04049	RAF1	S222	L215F	215	Missense	distal	-7	no	13.804	14.056	PhosphoSitePlus;EPSD	COSMIC	7.934	Up-regulation
TKL_RAF_RAF_RAF1_ST	Q02750	MAP2K1	P04049	RAF1	S222	Y229H	229	Missense	distal	7	no	13.804	14.252	PhosphoSitePlus;EPSD	COSMIC	7.934	Up-regulation
TKL_RAF_RAF_RAF1_ST	Q02750	MAP2K1	P04049	RAF1	S222	S218F	218	Missense	distal	-4	no	13.804	11.559	PhosphoSitePlus;EPSD	COSMIC	7.934	Down-regulation
TKL_RAF_RAF_RAF1_ST	Q02750	MAP2K1	P04049	RAF1	T292	P293S	293	Missense	proximal	1	no	9.208	8.777	EPSD	COSMIC	7.934	Down-regulation
TKL_RAF_RAF_RAF1_ST	Q02750	MAP2K1	P04049	RAF1	T292	R291K	291	Missense	proximal	-1	no	9.208	9.140	EPSD	COSMIC	7.934	Down-regulation
TKL_RAF_RAF_RAF1_ST	Q05639	EEF1A2	P04049	RAF1	S21	G14D	14	Missense	distal	-7	no	12.629	12.668	PhosphoSitePlus	COSMIC	7.934	Up-regulation
TKL_RAF_RAF_RAF1_ST	Q05639	EEF1A2	P04049	RAF1	S76	D74Y	74	Missense	proximal	-2	no	8.505	8.601	EPSD	COSMIC;GDSC;CCLE	7.934	Up-regulation
TKL_RAF_RAF_RAF1_ST	Q05639	EEF1A2	P04049	RAF1	S76	G70R	70	Missense	distal	-6	no	8.505	8.276	EPSD	COSMIC	7.934	Down-regulation
TKL_RAF_RAF_RAF1_ST	Q05639	EEF1A2	P04049	RAF1	S107	T104M	104	Missense	distal	-3	no	4.623	9.514	EPSD	COSMIC	7.934	Gain
TKL_RAF_RAF_RAF1_ST	Q05639	EEF1A2	P04049	RAF1	T279	P274L	274	Missense	distal	-5	no	10.255	10.505	EPSD	COSMIC	7.934	Up-regulation
TKL_RAF_RAF_RAF1_ST	Q05639	EEF1A2	P04049	RAF1	T279	P274S	274	Missense	distal	-5	no	10.255	10.387	EPSD	COSMIC	7.934	Up-regulation
TKL_RAF_RAF_RAF1_ST	Q05639	EEF1A2	P04049	RAF1	T279	A281V	281	Missense	proximal	2	no	10.255	9.990	EPSD	COSMIC;GDSC;CCLE	7.934	Down-regulation
TKL_RAF_RAF_RAF1_ST	Q05639	EEF1A2	P04049	RAF1	T279	P274R	274	Missense	distal	-5	no	10.255	10.482	EPSD	COSMIC	7.934	Up-regulation
TKL_RAF_RAF_RAF1_ST	Q05639	EEF1A2	P04049	RAF1	S358	I361T	361	Missense	distal	3	no	9.098	8.621	EPSD	COSMIC	7.934	Down-regulation
TKL_RAF_RAF_RAF1_ST	Q05639	EEF1A2	P04049	RAF1	S358	V360I	360	Missense	proximal	2	no	9.098	9.040	EPSD	COSMIC	7.934	Down-regulation
TKL_RAF_RAF_RAF1_ST	Q05639	EEF1A2	P04049	RAF1	T432	V435A	435	Missense	distal	3	no	10.550	9.920	EPSD	COSMIC	7.934	Down-regulation
TKL_RAF_RAF_RAF1_ST	P01106	MYC	P04049	RAF1	S6	N9H	9	Missense	distal	3	no	8.735	8.284	EPSD	COSMIC	7.934	Down-regulation
TKL_RAF_RAF_RAF1_ST	P01106	MYC	P04049	RAF1	S6	N11S	11	Missense	distal	5	no	8.735	8.362	EPSD	COSMIC	7.934	Down-regulation
TKL_RAF_RAF_RAF1_ST	P01106	MYC	P04049	RAF1	S6	Y12C	12	Missense	distal	6	no	8.735	8.819	EPSD	COSMIC	7.934	Up-regulation
TKL_RAF_RAF_RAF1_ST	P01106	MYC	P04049	RAF1	S6	N11Y	11	Missense	distal	5	no	8.735	8.670	EPSD	COSMIC	7.934	Down-regulation
TKL_RAF_RAF_RAF1_ST	P01106	MYC	P04049	RAF1	S6	F7L	7	Missense	proximal	1	no	8.735	8.669	EPSD	COSMIC	7.934	Down-regulation
TKL_RAF_RAF_RAF1_ST	P01106	MYC	P04049	RAF1	S6	S6R	6	Missense	central	0	yes	8.735	0.000	EPSD	COSMIC	7.934	Loss
TKL_RAF_RAF_RAF1_ST	P01106	MYC	P04049	RAF1	S6	N11D	11	Missense	distal	5	no	8.735	9.014	EPSD	COSMIC	7.934	Up-regulation
TKL_RAF_RAF_RAF1_ST	P01106	MYC	P04049	RAF1	S6	P2S	2	Missense	distal	-4	no	8.735	12.000	EPSD	COSMIC	7.934	Up-regulation
TKL_RAF_RAF_RAF1_ST	P01106	MYC	P04049	RAF1	S6	S6N	6	Missense	central	0	yes	8.735	0.000	EPSD	COSMIC;CCLE	7.934	Loss
TKL_RAF_RAF_RAF1_ST	P01106	MYC	P04049	RAF1	S6	V5I	5	Missense	proximal	-1	no	8.735	8.797	EPSD	COSMIC;CCLE	7.934	Up-regulation
TKL_RAF_RAF_RAF1_ST	P01106	MYC	P04049	RAF1	S6	V5A	5	Missense	proximal	-1	no	8.735	8.903	EPSD	COSMIC;CCLE	7.934	Up-regulation
TKL_RAF_RAF_RAF1_ST	P01106	MYC	P04049	RAF1	S6	R10K	10	Missense	distal	4	no	8.735	8.924	EPSD	COSMIC	7.934	Up-regulation
TKL_RAF_RAF_RAF1_ST	P01106	MYC	P04049	RAF1	S6	F7I	7	Missense	proximal	1	no	8.735	8.842	EPSD	COSMIC	7.934	Up-regulation
TKL_RAF_RAF_RAF1_ST	P01106	MYC	P04049	RAF1	S6	R10G	10	Missense	distal	4	no	8.735	10.262	EPSD	COSMIC	7.934	Up-regulation
TKL_RAF_RAF_RAF1_ST	P01106	MYC	P04049	RAF1	S6	R10M	10	Missense	distal	4	no	8.735	8.969	EPSD	COSMIC	7.934	Up-regulation
TKL_RAF_RAF_RAF1_ST	P01106	MYC	P04049	RAF1	S6	L3R	3	Missense	distal	-3	no	8.735	11.320	EPSD	COSMIC	7.934	Up-regulation
TKL_RAF_RAF_RAF1_ST	P01106	MYC	P04049	RAF1	S6	N9S	9	Missense	distal	3	no	8.735	6.871	EPSD	COSMIC	7.934	Loss
TKL_RAF_RAF_RAF1_ST	P01106	MYC	P04049	RAF1	S6	Y12S	12	Missense	distal	6	no	8.735	8.925	EPSD	COSMIC;CCLE	7.934	Up-regulation
TKL_RAF_RAF_RAF1_ST	P01106	MYC	P04049	RAF1	S6	R10W	10	Missense	distal	4	no	8.735	9.615	EPSD	COSMIC	7.934	Up-regulation
TKL_RAF_RAF_RAF1_ST	P01106	MYC	P04049	RAF1	S6	L3F	3	Missense	distal	-3	no	8.735	7.145	EPSD	COSMIC	7.934	Loss
TKL_RAF_RAF_RAF1_ST	P01106	MYC	P04049	RAF1	S6	S6D	6	Missense	central	0	yes	8.735	0.000	EPSD	COSMIC	7.934	Loss
TKL_RAF_RAF_RAF1_ST	P01106	MYC	P04049	RAF1	S6	S6G	6	Missense	central	0	yes	8.735	0.000	EPSD	COSMIC	7.934	Loss
TKL_RAF_RAF_RAF1_ST	P01106	MYC	P04049	RAF1	S6	Y12N	12	Missense	distal	6	no	8.735	8.591	EPSD	COSMIC	7.934	Down-regulation
TKL_RAF_RAF_RAF1_ST	P01106	MYC	P04049	RAF1	T8	N9H	9	Missense	proximal	1	no	14.011	13.845	PhosphoSitePlus	COSMIC	7.934	Down-regulation
TKL_RAF_RAF_RAF1_ST	P01106	MYC	P04049	RAF1	T8	N11S	11	Missense	distal	3	no	14.011	12.148	PhosphoSitePlus	COSMIC	7.934	Down-regulation
TKL_RAF_RAF_RAF1_ST	P01106	MYC	P04049	RAF1	T8	Y12C	12	Missense	distal	4	no	14.011	14.087	PhosphoSitePlus	COSMIC	7.934	Up-regulation
TKL_RAF_RAF_RAF1_ST	P01106	MYC	P04049	RAF1	T8	N11Y	11	Missense	distal	3	no	14.011	13.136	PhosphoSitePlus	COSMIC	7.934	Down-regulation
TKL_RAF_RAF_RAF1_ST	P01106	MYC	P04049	RAF1	T8	F7L	7	Missense	proximal	-1	no	14.011	14.185	PhosphoSitePlus	COSMIC	7.934	Up-regulation
TKL_RAF_RAF_RAF1_ST	P01106	MYC	P04049	RAF1	T8	S6R	6	Missense	proximal	-2	no	14.011	13.978	PhosphoSitePlus	COSMIC	7.934	Down-regulation
TKL_RAF_RAF_RAF1_ST	P01106	MYC	P04049	RAF1	T8	N11D	11	Missense	distal	3	no	14.011	13.550	PhosphoSitePlus	COSMIC	7.934	Down-regulation
TKL_RAF_RAF_RAF1_ST	P01106	MYC	P04049	RAF1	T8	P2S	2	Missense	distal	-6	no	14.011	13.705	PhosphoSitePlus	COSMIC	7.934	Down-regulation
TKL_RAF_RAF_RAF1_ST	P01106	MYC	P04049	RAF1	T8	S6N	6	Missense	proximal	-2	no	14.011	13.978	PhosphoSitePlus	COSMIC;CCLE	7.934	Down-regulation
TKL_RAF_RAF_RAF1_ST	P01106	MYC	P04049	RAF1	T8	S6T	6	Missense	proximal	-2	no	14.011	13.981	PhosphoSitePlus	COSMIC;CCLE	7.934	Down-regulation
TKL_RAF_RAF_RAF1_ST	P01106	MYC	P04049	RAF1	T8	V5I	5	Missense	distal	-3	no	14.011	15.933	PhosphoSitePlus	COSMIC;CCLE	7.934	Up-regulation
TKL_RAF_RAF_RAF1_ST	P01106	MYC	P04049	RAF1	T8	V5A	5	Missense	distal	-3	no	14.011	12.413	PhosphoSitePlus	COSMIC;CCLE	7.934	Down-regulation
TKL_RAF_RAF_RAF1_ST	P01106	MYC	P04049	RAF1	T8	R10K	10	Missense	proximal	2	no	14.011	14.087	PhosphoSitePlus	COSMIC	7.934	Up-regulation
TKL_RAF_RAF_RAF1_ST	P01106	MYC	P04049	RAF1	T8	F7I	7	Missense	proximal	-1	no	14.011	13.909	PhosphoSitePlus	COSMIC	7.934	Down-regulation
TKL_RAF_RAF_RAF1_ST	P01106	MYC	P04049	RAF1	T8	R10G	10	Missense	proximal	2	no	14.011	13.985	PhosphoSitePlus	COSMIC	7.934	Down-regulation
TKL_RAF_RAF_RAF1_ST	P01106	MYC	P04049	RAF1	T8	L14V	14	Missense	distal	6	no	14.011	13.716	PhosphoSitePlus	COSMIC	7.934	Down-regulation
TKL_RAF_RAF_RAF1_ST	P01106	MYC	P04049	RAF1	T8	R10M	10	Missense	proximal	2	no	14.011	14.469	PhosphoSitePlus	COSMIC	7.934	Up-regulation
TKL_RAF_RAF_RAF1_ST	P01106	MYC	P04049	RAF1	T8	L3R	3	Missense	distal	-5	no	14.011	13.988	PhosphoSitePlus	COSMIC	7.934	Down-regulation
TKL_RAF_RAF_RAF1_ST	P01106	MYC	P04049	RAF1	T8	N9S	9	Missense	proximal	1	no	14.011	13.525	PhosphoSitePlus	COSMIC	7.934	Down-regulation
TKL_RAF_RAF_RAF1_ST	P01106	MYC	P04049	RAF1	T8	Y12S	12	Missense	distal	4	no	14.011	14.957	PhosphoSitePlus	COSMIC;CCLE	7.934	Up-regulation
TKL_RAF_RAF_RAF1_ST	P01106	MYC	P04049	RAF1	T8	R10W	10	Missense	proximal	2	no	14.011	14.428	PhosphoSitePlus	COSMIC	7.934	Up-regulation
TKL_RAF_RAF_RAF1_ST	P01106	MYC	P04049	RAF1	T8	L3F	3	Missense	distal	-5	no	14.011	13.793	PhosphoSitePlus	COSMIC	7.934	Down-regulation
TKL_RAF_RAF_RAF1_ST	P01106	MYC	P04049	RAF1	T8	S6D	6	Missense	proximal	-2	no	14.011	13.884	PhosphoSitePlus	COSMIC	7.934	Down-regulation
TKL_RAF_RAF_RAF1_ST	P01106	MYC	P04049	RAF1	T8	S6G	6	Missense	proximal	-2	no	14.011	14.002	PhosphoSitePlus	COSMIC	7.934	Down-regulation
TKL_RAF_RAF_RAF1_ST	P01106	MYC	P04049	RAF1	T8	D15G	15	Missense	distal	7	no	14.011	13.551	PhosphoSitePlus	COSMIC	7.934	Down-regulation
TKL_RAF_RAF_RAF1_ST	P01106	MYC	P04049	RAF1	T8	L14F	14	Missense	distal	6	no	14.011	13.518	PhosphoSitePlus	COSMIC	7.934	Down-regulation
TKL_RAF_RAF_RAF1_ST	P01106	MYC	P04049	RAF1	T8	Y12N	12	Missense	distal	4	no	14.011	13.649	PhosphoSitePlus	COSMIC	7.934	Down-regulation
TKL_RAF_RAF_RAF1_ST	P01106	MYC	P04049	RAF1	S62	P59L	59	Missense	distal	-3	no	6.738	11.053	EPSD	COSMIC;CCLE	7.934	Gain
TKL_RAF_RAF_RAF1_ST	P01106	MYC	P04049	RAF1	S62	P59A	59	Missense	distal	-3	no	6.738	8.490	EPSD	COSMIC;CCLE	7.934	Gain
TKL_RAF_RAF_RAF1_ST	P01106	MYC	P04049	RAF1	S62	P59R	59	Missense	distal	-3	no	6.738	13.639	EPSD	COSMIC	7.934	Gain
TKL_RAF_RAF_RAF1_ST	P01106	MYC	P04049	RAF1	S62	P59S	59	Missense	distal	-3	no	6.738	9.298	EPSD	COSMIC;CCLE	7.934	Gain
TKL_RAF_RAF_RAF1_ST	P01106	MYC	P04049	RAF1	S62	P59Q	59	Missense	distal	-3	no	6.738	12.045	EPSD	COSMIC;CCLE	7.934	Gain
TKL_RAF_RAF_RAF1_ST	P01106	MYC	P04049	RAF1	S64	P60S	60	Missense	distal	-4	no	6.018	9.284	EPSD	COSMIC	7.934	Gain
TKL_RAF_RAF_RAF1_ST	P01106	MYC	P04049	RAF1	S159	K157T	157	Missense	proximal	-2	no	8.148	8.155	EPSD	COSMIC	7.934	Up-regulation
TKL_RAF_RAF_RAF1_ST	P01106	MYC	P04049	RAF1	S159	A155S	155	Missense	distal	-4	no	8.148	9.633	EPSD	COSMIC	7.934	Up-regulation
TKL_RAF_RAF_RAF1_ST	P01106	MYC	P04049	RAF1	S159	K157N	157	Missense	proximal	-2	no	8.148	8.151	EPSD	COSMIC	7.934	Up-regulation
TKL_RAF_RAF_RAF1_ST	P01106	MYC	P04049	RAF1	S159	A155T	155	Missense	distal	-4	no	8.148	7.190	EPSD	COSMIC	7.934	Loss
TKL_RAF_RAF_RAF1_ST	P01106	MYC	P04049	RAF1	S159	Y152N	152	Missense	distal	-7	no	8.148	8.536	EPSD	COSMIC	7.934	Up-regulation
TKL_RAF_RAF_RAF1_ST	P01106	MYC	P04049	RAF1	S159	N163K	163	Missense	distal	4	no	8.148	7.876	EPSD	COSMIC	7.934	Loss
TKL_RAF_RAF_RAF1_ST	P01106	MYC	P04049	RAF1	S159	P162R	162	Missense	distal	3	no	8.148	8.287	EPSD	COSMIC	7.934	Up-regulation
TKL_RAF_RAF_RAF1_ST	P01106	MYC	P04049	RAF1	S159	A154T	154	Missense	distal	-5	no	8.148	8.074	EPSD	COSMIC	7.934	Down-regulation
TKL_RAF_RAF_RAF1_ST	P01106	MYC	P04049	RAF1	S159	G160D	160	Missense	proximal	1	no	8.148	8.078	EPSD	COSMIC	7.934	Down-regulation
TKL_RAF_RAF_RAF1_ST	P01106	MYC	P04049	RAF1	S159	S159N	159	Missense	central	0	yes	8.148	0.000	EPSD	COSMIC	7.934	Loss
TKL_RAF_RAF_RAF1_ST	P01106	MYC	P04049	RAF1	S159	A165S	165	Missense	distal	6	no	8.148	8.412	EPSD	COSMIC	7.934	Up-regulation
TKL_RAF_RAF_RAF1_ST	P01106	MYC	P04049	RAF1	S159	A165T	165	Missense	distal	6	no	8.148	8.146	EPSD	COSMIC	7.934	Down-regulation
TKL_RAF_RAF_RAF1_ST	P01106	MYC	P04049	RAF1	S159	D158G	158	Missense	proximal	-1	no	8.148	8.357	EPSD	COSMIC	7.934	Up-regulation
TKL_RAF_RAF_RAF1_ST	P01106	MYC	P04049	RAF1	S159	R166H	166	Missense	distal	7	no	8.148	8.152	EPSD	COSMIC	7.934	Up-regulation
TKL_RAF_RAF_RAF1_ST	P01106	MYC	P04049	RAF1	S159	S161N	161	Missense	proximal	2	no	8.148	7.105	EPSD	COSMIC	7.934	Loss
TKL_RAF_RAF_RAF1_ST	P01106	MYC	P04049	RAF1	S159	R156G	156	Missense	distal	-3	no	8.148	0.639	EPSD	COSMIC	7.934	Loss
TKL_RAF_RAF_RAF1_ST	P01106	MYC	P04049	RAF1	S159	A154G	154	Missense	distal	-5	no	8.148	7.979	EPSD	COSMIC	7.934	Down-regulation
TKL_RAF_RAF_RAF1_ST	P01106	MYC	P04049	RAF1	S159	S159R	159	Missense	central	0	yes	8.148	0.000	EPSD	COSMIC	7.934	Loss
TKL_RAF_RAF_RAF1_ST	P01106	MYC	P04049	RAF1	S159	Q153H	153	Missense	distal	-6	no	8.148	8.529	EPSD	COSMIC	7.934	Up-regulation
TKL_RAF_RAF_RAF1_ST	P01106	MYC	P04049	RAF1	S159	A165D	165	Missense	distal	6	no	8.148	7.874	EPSD	COSMIC	7.934	Loss
TKL_RAF_RAF_RAF1_ST	P01106	MYC	P04049	RAF1	S202	P198S	198	Missense	distal	-4	no	9.051	12.317	EPSD	COSMIC	7.934	Up-regulation
TKL_RAF_RAF_RAF1_ST	P01106	MYC	P04049	RAF1	S202	S203R	203	Missense	proximal	1	no	9.051	9.066	EPSD	COSMIC	7.934	Up-regulation
TKL_RAF_RAF_RAF1_ST	P01106	MYC	P04049	RAF1	S202	P196S	196	Missense	distal	-6	no	9.051	8.745	EPSD	COSMIC	7.934	Down-regulation
TKL_RAF_RAF_RAF1_ST	P01106	MYC	P04049	RAF1	S202	S203N	203	Missense	proximal	1	no	9.051	9.537	EPSD	COSMIC;CCLE	7.934	Up-regulation
TKL_RAF_RAF_RAF1_ST	P01106	MYC	P04049	RAF1	S202	Y197D	197	Missense	distal	-5	no	9.051	8.877	EPSD	COSMIC	7.934	Down-regulation
TKL_RAF_RAF_RAF1_ST	P01106	MYC	P04049	RAF1	S202	S203T	203	Missense	proximal	1	no	9.051	9.188	EPSD	COSMIC	7.934	Up-regulation
TKL_RAF_RAF_RAF1_ST	P01106	MYC	P04049	RAF1	S202	F195L	195	Missense	distal	-7	no	9.051	8.799	EPSD	COSMIC	7.934	Down-regulation
TKL_RAF_RAF_RAF1_ST	P01106	MYC	P04049	RAF1	S202	S203I	203	Missense	proximal	1	no	9.051	9.287	EPSD	COSMIC	7.934	Up-regulation
TKL_RAF_RAF_RAF1_ST	P01106	MYC	P04049	RAF1	S202	P205S	205	Missense	distal	3	no	9.051	7.889	EPSD	COSMIC	7.934	Loss
TKL_RAF_RAF_RAF1_ST	P01106	MYC	P04049	RAF1	S202	N200I	200	Missense	proximal	-2	no	9.051	9.080	EPSD	COSMIC	7.934	Up-regulation
TKL_RAF_RAF_RAF1_ST	P01106	MYC	P04049	RAF1	S202	S204A	204	Missense	proximal	2	no	9.051	9.840	EPSD	COSMIC	7.934	Up-regulation
TKL_RAF_RAF_RAF1_ST	P01106	MYC	P04049	RAF1	S202	S207P	207	Missense	distal	5	no	9.051	9.710	EPSD	COSMIC	7.934	Up-regulation
TKL_RAF_RAF_RAF1_ST	P01106	MYC	P04049	RAF1	T343	S347F	347	Missense	distal	4	no	10.530	8.809	EPSD	COSMIC	7.934	Down-regulation
TKL_RAF_RAF_RAF1_ST	P01106	MYC	P04049	RAF1	T343	S337T	337	Missense	distal	-6	no	10.530	10.767	EPSD	COSMIC	7.934	Up-regulation
TKL_RAF_RAF_RAF1_ST	P01106	MYC	P04049	RAF1	T343	I336V	336	Missense	distal	-7	no	10.530	10.500	EPSD	COSMIC	7.934	Down-regulation
TKL_RAF_RAF_RAF1_ST	O14974	PPP1R12A	P04049	RAF1	T381	A378S	378	Missense	distal	-3	no	7.652	8.460	EPSD	COSMIC	7.934	Gain
TKL_RAF_RAF_RAF1_ST	O14974	PPP1R12A	P04049	RAF1	S472	R469C	469	Missense	distal	-3	no	8.586	1.593	EPSD	COSMIC	7.934	Loss
TKL_RAF_RAF_RAF1_ST	O14974	PPP1R12A	P04049	RAF1	S472	A465S	465	Missense	distal	-7	no	8.586	8.673	EPSD	COSMIC	7.934	Up-regulation
TKL_RAF_RAF_RAF1_ST	O14974	PPP1R12A	P04049	RAF1	S472	S478C	478	Missense	distal	6	no	8.586	8.480	EPSD	COSMIC	7.934	Down-regulation
TKL_RAF_RAF_RAF1_ST	O14974	PPP1R12A	P04049	RAF1	S520	T524A	524	Missense	distal	4	no	8.204	8.100	EPSD	COSMIC;GDSC;CCLE	7.934	Down-regulation
TKL_RAF_RAF_RAF1_ST	O14974	PPP1R12A	P04049	RAF1	S525	T524A	524	Missense	proximal	-1	no	10.526	10.618	EPSD	COSMIC;GDSC;CCLE	7.934	Up-regulation
TKL_RAF_RAF_RAF1_ST	O14974	PPP1R12A	P04049	RAF1	S585	T590R	590	Missense	distal	5	no	9.716	9.778	EPSD	COSMIC	7.934	Up-regulation
TKL_RAF_RAF_RAF1_ST	O14974	PPP1R12A	P04049	RAF1	S601	T598M	598	Missense	distal	-3	no	4.526	9.416	EPSD	COSMIC;CCLE	7.934	Gain
TKL_RAF_RAF_RAF1_ST	O14974	PPP1R12A	P04049	RAF1	T696	R694I	694	Missense	proximal	-2	no	13.629	13.658	PhosphoSitePlus	COSMIC	7.934	Up-regulation
TKL_RAF_RAF_RAF1_ST	O14974	PPP1R12A	P04049	RAF1	S716	R718Q	718	Missense	proximal	2	no	7.331	8.749	EPSD	COSMIC	7.934	Gain
TKL_RAF_RAF_RAF1_ST	O14974	PPP1R12A	P04049	RAF1	S759	Y766C	766	Missense	distal	7	no	9.199	9.496	EPSD	COSMIC	7.934	Up-regulation
TKL_RAF_RAF_RAF1_ST	O14974	PPP1R12A	P04049	RAF1	T892	G898D	898	Missense	distal	6	no	11.068	10.622	EPSD	COSMIC	7.934	Down-regulation
TKL_RAF_RAF_RAF1_ST	O14974	PPP1R12A	P04049	RAF1	T892	R889G	889	Missense	distal	-3	no	11.068	3.558	EPSD	COSMIC	7.934	Loss
TKL_RAF_RAF_RAF1_ST	O14974	PPP1R12A	P04049	RAF1	T892	S888F	888	Missense	distal	-4	no	11.068	8.822	EPSD	COSMIC	7.934	Down-regulation
CAMK_MAPKAPK_MK2_MAPKAPK2_ST	Q8N5C8	TAB3	P49137	MAPKAPK2	S103	H100P	100	Missense	distal	-3	no	12.834	12.929	EPSD	COSMIC	11.681	Up-regulation
CAMK_MAPKAPK_MK2_MAPKAPK2_ST	Q8N5C8	TAB3	P49137	MAPKAPK2	S103	S101I	101	Missense	proximal	-2	no	12.834	8.492	EPSD	COSMIC	11.681	Loss
CAMK_MAPKAPK_MK2_MAPKAPK2_ST	Q8N5C8	TAB3	P49137	MAPKAPK2	S103	R96Q	96	Missense	distal	-7	no	12.834	12.921	EPSD	COSMIC	11.681	Up-regulation
CAMK_MAPKAPK_MK2_MAPKAPK2_ST	Q8N5C8	TAB3	P49137	MAPKAPK2	S103	G105V	105	Missense	proximal	2	no	12.834	12.934	EPSD	COSMIC	11.681	Up-regulation
CAMK_MAPKAPK_MK2_MAPKAPK2_ST	Q8N5C8	TAB3	P49137	MAPKAPK2	S356	L351F	351	Missense	distal	-5	no	12.174	11.476	EPSD	COSMIC	11.681	Loss
CAMK_MAPKAPK_MK2_MAPKAPK2_ST	Q8N5C8	TAB3	P49137	MAPKAPK2	S357	L351F	351	Missense	distal	-6	no	12.050	12.127	EPSD	COSMIC	11.681	Up-regulation
CAMK_MAPKAPK_MK2_MAPKAPK2_ST	Q8N5C8	TAB3	P49137	MAPKAPK2	S385	P386S	386	Missense	proximal	1	no	18.895	18.784	EPSD	COSMIC	11.681	Down-regulation
CAMK_MAPKAPK_MK2_MAPKAPK2_ST	Q8N5C8	TAB3	P49137	MAPKAPK2	S385	P384H	384	Missense	proximal	-1	no	18.895	18.906	EPSD	COSMIC	11.681	Up-regulation
CAMK_MAPKAPK_MK2_MAPKAPK2_ST	Q8N5C8	TAB3	P49137	MAPKAPK2	S385	S388T	388	Missense	distal	3	no	18.895	18.968	EPSD	COSMIC	11.681	Up-regulation
CAMK_MAPKAPK_MK2_MAPKAPK2_ST	Q8N5C8	TAB3	P49137	MAPKAPK2	S385	A379T	379	Missense	distal	-6	no	18.895	18.864	EPSD	COSMIC	11.681	Down-regulation
CAMK_MAPKAPK_MK2_MAPKAPK2_ST	Q8N5C8	TAB3	P49137	MAPKAPK2	S409	S409A	409	Missense	central	0	yes	15.751	0.000	EPSD	COSMIC	11.681	Loss
CAMK_MAPKAPK_MK2_MAPKAPK2_ST	Q8N5C8	TAB3	P49137	MAPKAPK2	S411	S409A	409	Missense	proximal	-2	no	12.529	10.934	EPSD	COSMIC	11.681	Loss
CAMK_MAPKAPK_MK2_MAPKAPK2_ST	Q8N5C8	TAB3	P49137	MAPKAPK2	S415	S409A	409	Missense	distal	-6	no	17.875	17.890	EPSD	COSMIC	11.681	Up-regulation
CAMK_MAPKAPK_MK2_MAPKAPK2_ST	Q8N5C8	TAB3	P49137	MAPKAPK2	S442	C439Y	439	Missense	distal	-3	no	9.256	11.915	EPSD	COSMIC	11.681	Gain
CAMK_MAPKAPK_MK2_MAPKAPK2_ST	Q8N5C8	TAB3	P49137	MAPKAPK2	S444	P451S	451	Missense	distal	7	no	15.072	14.955	EPSD	COSMIC	11.681	Down-regulation
CAMK_MAPKAPK_MK2_MAPKAPK2_ST	Q8N5C8	TAB3	P49137	MAPKAPK2	S444	T440I	440	Missense	distal	-4	no	15.072	15.204	EPSD	COSMIC	11.681	Up-regulation
CAMK_MAPKAPK_MK2_MAPKAPK2_ST	Q8N5C8	TAB3	P49137	MAPKAPK2	S444	C439Y	439	Missense	distal	-5	no	15.072	14.704	EPSD	COSMIC	11.681	Down-regulation
CAMK_MAPKAPK_MK2_MAPKAPK2_ST	Q8N5C8	TAB3	P49137	MAPKAPK2	S504	G497E	497	Missense	distal	-7	no	11.715	11.657	EPSD	COSMIC	11.681	Loss
CAMK_MAPKAPK_MK2_MAPKAPK2_ST	Q8N5C8	TAB3	P49137	MAPKAPK2	S563	V562L	562	Missense	proximal	-1	no	17.200	17.198	EPSD	COSMIC	11.681	Down-regulation
CAMK_MAPKAPK_MK2_MAPKAPK2_ST	Q8N5C8	TAB3	P49137	MAPKAPK2	S645	R639K	639	Missense	distal	-6	no	16.864	16.920	EPSD	COSMIC	11.681	Up-regulation
CAMK_MAPKAPK_MK2_MAPKAPK2_ST	Q8N5C8	TAB3	P49137	MAPKAPK2	S645	K640E	640	Missense	distal	-5	no	16.864	17.471	EPSD	COSMIC	11.681	Up-regulation
CAMK_MAPKAPK_MK2_MAPKAPK2_ST	Q8N5C8	TAB3	P49137	MAPKAPK2	S669	R674H	674	Missense	distal	5	no	17.529	17.835	EPSD	COSMIC	11.681	Up-regulation
CAMK_MAPKAPK_MK2_MAPKAPK2_ST	Q8N5C8	TAB3	P49137	MAPKAPK2	S669	R674C	674	Missense	distal	5	no	17.529	17.755	EPSD	COSMIC	11.681	Up-regulation
CAMK_MAPKAPK_MK2_MAPKAPK2_ST	P30305	CDC25B	P49137	MAPKAPK2	S50	A47P	47	Missense	distal	-3	no	8.342	12.898	EPSD	COSMIC	11.681	Gain
CAMK_MAPKAPK_MK2_MAPKAPK2_ST	P30305	CDC25B	P49137	MAPKAPK2	S91	R93W	93	Missense	proximal	2	no	13.750	13.440	EPSD	COSMIC	11.681	Down-regulation
CAMK_MAPKAPK_MK2_MAPKAPK2_ST	P30305	CDC25B	P49137	MAPKAPK2	S91	S89P	89	Missense	proximal	-2	no	13.750	10.519	EPSD	COSMIC	11.681	Loss
CAMK_MAPKAPK_MK2_MAPKAPK2_ST	P30305	CDC25B	P49137	MAPKAPK2	S117	A124E	124	Missense	distal	7	no	13.328	13.205	EPSD	COSMIC	11.681	Down-regulation
CAMK_MAPKAPK_MK2_MAPKAPK2_ST	P30305	CDC25B	P49137	MAPKAPK2	T167	V162L	162	Missense	distal	-5	no	12.481	12.789	EPSD	COSMIC	11.681	Up-regulation
CAMK_MAPKAPK_MK2_MAPKAPK2_ST	P30305	CDC25B	P49137	MAPKAPK2	S169	V162L	162	Missense	distal	-7	no	12.723	12.721	PhosphoSitePlus;EPSD	COSMIC	11.681	Down-regulation
CAMK_MAPKAPK_MK2_MAPKAPK2_ST	P30305	CDC25B	P49137	MAPKAPK2	S169	R175Q	175	Missense	distal	6	no	12.723	12.703	PhosphoSitePlus;EPSD	COSMIC;GDSC	11.681	Down-regulation
CAMK_MAPKAPK_MK2_MAPKAPK2_ST	P30305	CDC25B	P49137	MAPKAPK2	S178	A184V	184	Missense	distal	6	no	17.061	17.047	EPSD	COSMIC	11.681	Down-regulation
CAMK_MAPKAPK_MK2_MAPKAPK2_ST	P30305	CDC25B	P49137	MAPKAPK2	S178	R175Q	175	Missense	distal	-3	no	17.061	11.297	EPSD	COSMIC;GDSC	11.681	Loss
CAMK_MAPKAPK_MK2_MAPKAPK2_ST	P30305	CDC25B	P49137	MAPKAPK2	S178	S178N	178	Missense	central	0	yes	17.061	0.000	EPSD	COSMIC;GDSC;CCLE	11.681	Loss
CAMK_MAPKAPK_MK2_MAPKAPK2_ST	P30305	CDC25B	P49137	MAPKAPK2	S229	S230F	230	Missense	proximal	1	no	12.727	12.484	EPSD	COSMIC	11.681	Down-regulation
CAMK_MAPKAPK_MK2_MAPKAPK2_ST	P30305	CDC25B	P49137	MAPKAPK2	S230	L237H	237	Missense	distal	7	no	16.350	16.270	EPSD	COSMIC	11.681	Down-regulation
CAMK_MAPKAPK_MK2_MAPKAPK2_ST	P30305	CDC25B	P49137	MAPKAPK2	S230	S230F	230	Missense	central	0	yes	16.350	0.000	EPSD	COSMIC	11.681	Loss
CAMK_MAPKAPK_MK2_MAPKAPK2_ST	P30305	CDC25B	P49137	MAPKAPK2	S323	S323N	323	Missense	central	0	yes	19.707	0.000	EPSD;PhosphoSitePlus	COSMIC	11.681	Loss
CAMK_MAPKAPK_MK2_MAPKAPK2_ST	P30305	CDC25B	P49137	MAPKAPK2	S323	P325L	325	Missense	proximal	2	no	19.707	19.484	EPSD;PhosphoSitePlus	COSMIC	11.681	Down-regulation
CAMK_MAPKAPK_MK2_MAPKAPK2_ST	P30305	CDC25B	P49137	MAPKAPK2	S323	R320G	320	Missense	distal	-3	no	19.707	9.047	EPSD;PhosphoSitePlus	COSMIC	11.681	Loss
CAMK_MAPKAPK_MK2_MAPKAPK2_ST	P30305	CDC25B	P49137	MAPKAPK2	S323	S321F	321	Missense	proximal	-2	no	19.707	14.280	EPSD;PhosphoSitePlus	COSMIC	11.681	Down-regulation
CAMK_MAPKAPK_MK2_MAPKAPK2_ST	P30305	CDC25B	P49137	MAPKAPK2	S323	R330Q	330	Missense	distal	7	no	19.707	19.344	EPSD;PhosphoSitePlus	COSMIC	11.681	Down-regulation
CAMK_MAPKAPK_MK2_MAPKAPK2_ST	P30305	CDC25B	P49137	MAPKAPK2	S323	P322L	322	Missense	proximal	-1	no	19.707	19.706	EPSD;PhosphoSitePlus	COSMIC	11.681	Down-regulation
CAMK_MAPKAPK_MK2_MAPKAPK2_ST	P30305	CDC25B	P49137	MAPKAPK2	S323	R317W	317	Missense	distal	-6	no	19.707	19.752	EPSD;PhosphoSitePlus	COSMIC	11.681	Up-regulation
CAMK_MAPKAPK_MK2_MAPKAPK2_ST	P30305	CDC25B	P49137	MAPKAPK2	S353	R352Q	352	Missense	proximal	-1	no	16.982	17.007	EPSD;PhosphoSitePlus	COSMIC	11.681	Up-regulation
CAMK_MAPKAPK_MK2_MAPKAPK2_ST	P30305	CDC25B	P49137	MAPKAPK2	S353	R350T	350	Missense	distal	-3	no	16.982	11.107	EPSD;PhosphoSitePlus	COSMIC	11.681	Loss
CAMK_MAPKAPK_MK2_MAPKAPK2_ST	P30305	CDC25B	P49137	MAPKAPK2	T355	R352Q	352	Missense	distal	-3	no	15.395	9.631	EPSD	COSMIC	11.681	Loss
CAMK_MAPKAPK_MK2_MAPKAPK2_ST	P30305	CDC25B	P49137	MAPKAPK2	T355	R350T	350	Missense	distal	-5	no	15.395	15.160	EPSD	COSMIC	11.681	Down-regulation
CAMK_MAPKAPK_MK2_MAPKAPK2_ST	P30305	CDC25B	P49137	MAPKAPK2	S375	S373N	373	Missense	proximal	-2	no	19.277	16.912	EPSD;PhosphoSitePlus	COSMIC	11.681	Down-regulation
CAMK_MAPKAPK_MK2_MAPKAPK2_ST	P30305	CDC25B	P49137	MAPKAPK2	S375	R372C	372	Missense	distal	-3	no	19.277	10.877	EPSD;PhosphoSitePlus	COSMIC	11.681	Loss
CAMK_MAPKAPK_MK2_MAPKAPK2_ST	P30305	CDC25B	P49137	MAPKAPK2	S375	V370I	370	Missense	distal	-5	no	19.277	19.396	EPSD;PhosphoSitePlus	COSMIC;GDSC;CCLE	11.681	Up-regulation
CAMK_MAPKAPK_MK2_MAPKAPK2_ST	P30305	CDC25B	P49137	MAPKAPK2	S375	E380K	380	Missense	distal	5	no	19.277	19.490	EPSD;PhosphoSitePlus	COSMIC	11.681	Up-regulation
CAMK_MAPKAPK_MK2_MAPKAPK2_ST	P30305	CDC25B	P49137	MAPKAPK2	S470	L477P	477	Missense	distal	7	no	11.585	12.059	EPSD	COSMIC	11.681	Gain
CAMK_MAPKAPK_MK2_MAPKAPK2_ST	P30305	CDC25B	P49137	MAPKAPK2	T561	R562W	562	Missense	proximal	1	no	12.938	12.810	EPSD	COSMIC	11.681	Down-regulation
CAMK_MAPKAPK_MK2_MAPKAPK2_ST	P30305	CDC25B	P49137	MAPKAPK2	T561	T556I	556	Missense	distal	-5	no	12.938	13.325	EPSD	COSMIC	11.681	Up-regulation
CAMK_MAPKAPK_MK2_MAPKAPK2_ST	P30305	CDC25B	P49137	MAPKAPK2	T561	R568Q	568	Missense	distal	7	no	12.938	12.575	EPSD	COSMIC	11.681	Down-regulation
CAMK_MAPKAPK_MK2_MAPKAPK2_ST	P30305	CDC25B	P49137	MAPKAPK2	T561	R558H	558	Missense	distal	-3	no	12.938	8.178	EPSD	COSMIC	11.681	Loss
CAMK_MAPKAPK_MK2_MAPKAPK2_ST	P30305	CDC25B	P49137	MAPKAPK2	T561	K560R	560	Missense	proximal	-1	no	12.938	12.917	EPSD	COSMIC	11.681	Down-regulation
CAMK_MAPKAPK_MK2_MAPKAPK2_ST	P30305	CDC25B	P49137	MAPKAPK2	S563	R562W	562	Missense	proximal	-1	no	12.463	12.481	EPSD	COSMIC	11.681	Up-regulation
CAMK_MAPKAPK_MK2_MAPKAPK2_ST	P30305	CDC25B	P49137	MAPKAPK2	S563	T556I	556	Missense	distal	-7	no	12.463	12.525	EPSD	COSMIC	11.681	Up-regulation
CAMK_MAPKAPK_MK2_MAPKAPK2_ST	P30305	CDC25B	P49137	MAPKAPK2	S563	R568Q	568	Missense	distal	5	no	12.463	12.682	EPSD	COSMIC	11.681	Up-regulation
CAMK_MAPKAPK_MK2_MAPKAPK2_ST	P30305	CDC25B	P49137	MAPKAPK2	S563	R570W	570	Missense	distal	7	no	12.463	12.191	EPSD	COSMIC	11.681	Down-regulation
CAMK_MAPKAPK_MK2_MAPKAPK2_ST	P30305	CDC25B	P49137	MAPKAPK2	S563	R558H	558	Missense	distal	-5	no	12.463	11.986	EPSD	COSMIC	11.681	Down-regulation
CAMK_MAPKAPK_MK2_MAPKAPK2_ST	P30305	CDC25B	P49137	MAPKAPK2	S563	K560R	560	Missense	distal	-3	no	12.463	17.587	EPSD	COSMIC	11.681	Up-regulation
CAMK_MAPKAPK_MK2_MAPKAPK2_ST	P30305	CDC25B	P49137	MAPKAPK2	S563	R570L	570	Missense	distal	7	no	12.463	12.079	EPSD	COSMIC	11.681	Down-regulation
CAMK_MAPKAPK_MK2_MAPKAPK2_ST	Q13151	HNRNPA0	P49137	MAPKAPK2	S84	A82V	82	Missense	proximal	-2	no	18.815	16.614	PhosphoSitePlus	COSMIC	11.681	Down-regulation
CAMK_MAPKAPK_MK2_MAPKAPK2_ST	Q13151	HNRNPA0	P49137	MAPKAPK2	S88	A82V	82	Missense	distal	-6	no	15.347	15.376	EPSD	COSMIC	11.681	Up-regulation
CAMK_MAPKAPK_MK2_MAPKAPK2_ST	P17302	GJA1	P49137	MAPKAPK2	S251	D245Y	245	Missense	distal	-6	no	12.263	12.302	EPSD	COSMIC	11.681	Up-regulation
CAMK_MAPKAPK_MK2_MAPKAPK2_ST	P17302	GJA1	P49137	MAPKAPK2	S251	P256T	256	Missense	distal	5	no	12.263	12.138	EPSD	COSMIC	11.681	Down-regulation
CAMK_MAPKAPK_MK2_MAPKAPK2_ST	P17302	GJA1	P49137	MAPKAPK2	S251	A253V	253	Missense	proximal	2	no	12.263	11.958	EPSD	COSMIC	11.681	Down-regulation
CAMK_MAPKAPK_MK2_MAPKAPK2_ST	P17302	GJA1	P49137	MAPKAPK2	S296	R299L	299	Missense	distal	3	no	16.244	16.197	EPSD	COSMIC;GDSC;CCLE	11.681	Down-regulation
CAMK_MAPKAPK_MK2_MAPKAPK2_ST	P17302	GJA1	P49137	MAPKAPK2	S296	N302S	302	Missense	distal	6	no	16.244	16.269	EPSD	COSMIC	11.681	Up-regulation
CAMK_MAPKAPK_MK2_MAPKAPK2_ST	P17302	GJA1	P49137	MAPKAPK2	S330	D336V	336	Missense	distal	6	no	12.334	12.342	EPSD	COSMIC	11.681	Up-regulation
CAMK_MAPKAPK_MK2_MAPKAPK2_ST	P17302	GJA1	P49137	MAPKAPK2	S365	P363L	363	Missense	proximal	-2	no	16.040	15.914	EPSD	COSMIC	11.681	Down-regulation
CAMK_MAPKAPK_MK2_MAPKAPK2_ST	P17302	GJA1	P49137	MAPKAPK2	S365	R370S	370	Missense	distal	5	no	16.040	16.021	EPSD	COSMIC	11.681	Down-regulation
CAMK_MAPKAPK_MK2_MAPKAPK2_ST	P17302	GJA1	P49137	MAPKAPK2	S369	P363L	363	Missense	distal	-6	no	17.238	17.269	EPSD	COSMIC	11.681	Up-regulation
CAMK_MAPKAPK_MK2_MAPKAPK2_ST	P17302	GJA1	P49137	MAPKAPK2	S369	R370S	370	Missense	proximal	1	no	17.238	17.214	EPSD	COSMIC	11.681	Down-regulation
CAMK_MAPKAPK_MK2_MAPKAPK2_ST	P17302	GJA1	P49137	MAPKAPK2	S372	R370S	370	Missense	proximal	-2	no	10.448	12.715	EPSD	COSMIC	11.681	Gain
CAMK_MAPKAPK_MK2_MAPKAPK2_ST	P17302	GJA1	P49137	MAPKAPK2	S373	R370S	370	Missense	distal	-3	no	17.666	11.337	EPSD	COSMIC	11.681	Loss
CAMK_MAPKAPK_MK2_MAPKAPK2_ST	P04792	HSPB1	P49137	MAPKAPK2	S15	P14S	14	Missense	proximal	-1	no	16.320	16.319	EPSD;PhosphoSitePlus	COSMIC	11.681	Down-regulation
CAMK_MAPKAPK_MK2_MAPKAPK2_ST	P04792	HSPB1	P49137	MAPKAPK2	S15	R20W	20	Missense	distal	5	no	16.320	16.539	EPSD;PhosphoSitePlus	COSMIC	11.681	Up-regulation
CAMK_MAPKAPK_MK2_MAPKAPK2_ST	P04792	HSPB1	P49137	MAPKAPK2	S15	R20Q	20	Missense	distal	5	no	16.320	16.539	EPSD;PhosphoSitePlus	COSMIC	11.681	Up-regulation
CAMK_MAPKAPK_MK2_MAPKAPK2_ST	P04792	HSPB1	P49137	MAPKAPK2	S15	F8L	8	Missense	distal	-7	no	16.320	16.263	EPSD;PhosphoSitePlus	COSMIC	11.681	Down-regulation
CAMK_MAPKAPK_MK2_MAPKAPK2_ST	P04792	HSPB1	P49137	MAPKAPK2	S49	S49G	49	Missense	central	0	yes	11.839	0.000	EPSD	COSMIC;CCLE	11.681	Loss
CAMK_MAPKAPK_MK2_MAPKAPK2_ST	P04792	HSPB1	P49137	MAPKAPK2	S49	S43L	43	Missense	distal	-6	no	11.839	11.871	EPSD	COSMIC	11.681	Up-regulation
CAMK_MAPKAPK_MK2_MAPKAPK2_ST	P04792	HSPB1	P49137	MAPKAPK2	S74	R75C	75	Missense	proximal	1	no	13.380	13.119	EPSD	COSMIC	11.681	Down-regulation
CAMK_MAPKAPK_MK2_MAPKAPK2_ST	P04792	HSPB1	P49137	MAPKAPK2	S78	R75C	75	Missense	distal	-3	no	17.170	8.771	PhosphoSitePlus;EPSD	COSMIC	11.681	Loss
CAMK_MAPKAPK_MK2_MAPKAPK2_ST	P04792	HSPB1	P49137	MAPKAPK2	S82	R75C	75	Missense	distal	-7	no	17.328	17.407	EPSD;PhosphoSitePlus	COSMIC	11.681	Up-regulation
CAMK_MAPKAPK_MK2_MAPKAPK2_ST	P04792	HSPB1	P49137	MAPKAPK2	S158	S154F	154	Missense	distal	-4	no	13.817	14.212	EPSD	COSMIC;GDSC;CCLE	11.681	Up-regulation
CAMK_MAPKAPK_MK2_MAPKAPK2_ST	P04792	HSPB1	P49137	MAPKAPK2	S158	T151A	151	Missense	distal	-7	no	13.817	13.838	EPSD	COSMIC;GDSC;CCLE	11.681	Up-regulation
CAMK_MAPKAPK_MK2_MAPKAPK2_ST	P53667	LIMK1	P49137	MAPKAPK2	S157	P155S	155	Missense	proximal	-2	no	9.165	12.396	EPSD	COSMIC	11.681	Gain
CAMK_MAPKAPK_MK2_MAPKAPK2_ST	P53667	LIMK1	P49137	MAPKAPK2	S210	G207R	207	Missense	distal	-3	no	4.810	15.470	EPSD	COSMIC	11.681	Gain
CAMK_MAPKAPK_MK2_MAPKAPK2_ST	P53667	LIMK1	P49137	MAPKAPK2	S286	S286I	286	Missense	central	0	yes	13.115	0.000	EPSD	COSMIC	11.681	Loss
CAMK_MAPKAPK_MK2_MAPKAPK2_ST	P53667	LIMK1	P49137	MAPKAPK2	S286	S286R	286	Missense	central	0	yes	13.115	0.000	EPSD	COSMIC	11.681	Loss
CAMK_MAPKAPK_MK2_MAPKAPK2_ST	P53667	LIMK1	P49137	MAPKAPK2	S286	S281N	281	Missense	distal	-5	no	13.115	12.417	EPSD	COSMIC;GDSC;CCLE	11.681	Down-regulation
CAMK_MAPKAPK_MK2_MAPKAPK2_ST	P53667	LIMK1	P49137	MAPKAPK2	S298	R295W	295	Missense	distal	-3	no	21.044	12.465	EPSD	COSMIC	11.681	Down-regulation
CAMK_MAPKAPK_MK2_MAPKAPK2_ST	P53667	LIMK1	P49137	MAPKAPK2	S323	R320L	320	Missense	distal	-3	no	21.826	16.735	PhosphoSitePlus	COSMIC;GDSC;CCLE	11.681	Down-regulation
CAMK_MAPKAPK_MK2_MAPKAPK2_ST	P53667	LIMK1	P49137	MAPKAPK2	S323	V326I	326	Missense	distal	3	no	21.826	21.776	PhosphoSitePlus	COSMIC	11.681	Down-regulation
CAMK_MAPKAPK_MK2_MAPKAPK2_ST	P53667	LIMK1	P49137	MAPKAPK2	S323	R320H	320	Missense	distal	-3	no	21.826	17.067	PhosphoSitePlus	COSMIC	11.681	Down-regulation
CAMK_MAPKAPK_MK2_MAPKAPK2_ST	P53667	LIMK1	P49137	MAPKAPK2	S323	E322D	322	Missense	proximal	-1	no	21.826	21.838	PhosphoSitePlus	COSMIC	11.681	Up-regulation
CAMK_MAPKAPK_MK2_MAPKAPK2_ST	P53667	LIMK1	P49137	MAPKAPK2	S637	G635S	635	Missense	proximal	-2	no	13.178	16.515	EPSD	COSMIC	11.681	Up-regulation
CAMK_MAPKAPK_MK2_MAPKAPK2_ST	P53667	LIMK1	P49137	MAPKAPK2	S637	G638R	638	Missense	proximal	1	no	13.178	13.621	EPSD	COSMIC	11.681	Up-regulation
CAMK_MAPKAPK_MK2_MAPKAPK2_ST	P53667	LIMK1	P49137	MAPKAPK2	S637	R634H	634	Missense	distal	-3	no	13.178	8.419	EPSD	COSMIC;GDSC	11.681	Loss
CAMK_MAPKAPK_MK2_MAPKAPK2_ST	P53667	LIMK1	P49137	MAPKAPK2	S637	P640S	640	Missense	distal	3	no	13.178	13.185	EPSD	COSMIC	11.681	Up-regulation
CAMK_MAPKAPK_MK2_MAPKAPK2_ST	Q96J92	WNK4	P49137	MAPKAPK2	S47	R44H	44	Missense	distal	-3	no	16.734	11.975	EPSD	COSMIC	11.681	Down-regulation
CAMK_MAPKAPK_MK2_MAPKAPK2_ST	Q96J92	WNK4	P49137	MAPKAPK2	S575	F569V	569	Missense	distal	-6	no	15.562	15.498	PhosphoSitePlus	COSMIC	11.681	Down-regulation
CAMK_MAPKAPK_MK2_MAPKAPK2_ST	Q96J92	WNK4	P49137	MAPKAPK2	S575	R572S	572	Missense	distal	-3	no	15.562	9.232	PhosphoSitePlus	COSMIC	11.681	Loss
CAMK_MAPKAPK_MK2_MAPKAPK2_ST	Q96J92	WNK4	P49137	MAPKAPK2	S575	R572C	572	Missense	distal	-3	no	15.562	7.162	PhosphoSitePlus	COSMIC	11.681	Loss
CAMK_MAPKAPK_MK2_MAPKAPK2_ST	Q96J92	WNK4	P49137	MAPKAPK2	S680	S674F	674	Missense	distal	-6	no	16.618	16.726	EPSD	COSMIC	11.681	Up-regulation
CAMK_MAPKAPK_MK2_MAPKAPK2_ST	Q96J92	WNK4	P49137	MAPKAPK2	S728	P727R	727	Missense	proximal	-1	no	11.762	11.751	EPSD	COSMIC	11.681	Down-regulation
CAMK_MAPKAPK_MK2_MAPKAPK2_ST	Q96J92	WNK4	P49137	MAPKAPK2	S728	G732E	732	Missense	distal	4	no	11.762	11.892	EPSD	COSMIC	11.681	Up-regulation
CAMK_MAPKAPK_MK2_MAPKAPK2_ST	Q96J92	WNK4	P49137	MAPKAPK2	S1035	P1042A	1042	Missense	distal	7	no	12.136	12.219	EPSD	COSMIC	11.681	Up-regulation
CAMK_MAPKAPK_MK2_MAPKAPK2_ST	Q96J92	WNK4	P49137	MAPKAPK2	S1201	R1199S	1199	Missense	proximal	-2	no	17.888	20.155	EPSD	COSMIC	11.681	Up-regulation
CAMK_MAPKAPK_MK2_MAPKAPK2_ST	P16220	CREB1	P49137	MAPKAPK2	S98	S103N	103	Missense	distal	5	no	14.856	15.095	EPSD	COSMIC	11.681	Up-regulation
CAMK_MAPKAPK_MK2_MAPKAPK2_ST	P16220	CREB1	P49137	MAPKAPK2	S98	R95I	95	Missense	distal	-3	no	14.856	9.567	EPSD	COSMIC	11.681	Loss
CAMK_MAPKAPK_MK2_MAPKAPK2_ST	P16220	CREB1	P49137	MAPKAPK2	S98	I102M	102	Missense	distal	4	no	14.856	14.948	EPSD	COSMIC	11.681	Up-regulation
CAMK_MAPKAPK_MK2_MAPKAPK2_ST	P16220	CREB1	P49137	MAPKAPK2	S133	L128R	128	Missense	distal	-5	no	17.252	16.911	PhosphoSitePlus	COSMIC	11.681	Down-regulation
CAMK_MAPKAPK_MK2_MAPKAPK2_ST	Q6JBY9	RCSD1	P49137	MAPKAPK2	S17	V12L	12	Missense	distal	-5	no	15.435	15.742	EPSD	COSMIC	11.681	Up-regulation
CAMK_MAPKAPK_MK2_MAPKAPK2_ST	Q6JBY9	RCSD1	P49137	MAPKAPK2	S17	S15L	15	Missense	proximal	-2	no	15.435	12.078	EPSD	COSMIC;GDSC;CCLE	11.681	Down-regulation
CAMK_MAPKAPK_MK2_MAPKAPK2_ST	Q6JBY9	RCSD1	P49137	MAPKAPK2	S17	D13G	13	Missense	distal	-4	no	15.435	15.512	EPSD	COSMIC	11.681	Up-regulation
CAMK_MAPKAPK_MK2_MAPKAPK2_ST	Q6JBY9	RCSD1	P49137	MAPKAPK2	S50	K46I	46	Missense	distal	-4	no	12.794	12.683	EPSD	COSMIC	11.681	Down-regulation
CAMK_MAPKAPK_MK2_MAPKAPK2_ST	Q6JBY9	RCSD1	P49137	MAPKAPK2	S50	S50F	50	Missense	central	0	yes	12.794	0.000	EPSD	COSMIC	11.681	Loss
CAMK_MAPKAPK_MK2_MAPKAPK2_ST	Q6JBY9	RCSD1	P49137	MAPKAPK2	S50	P48A	48	Missense	proximal	-2	no	12.794	14.431	EPSD	COSMIC	11.681	Up-regulation
CAMK_MAPKAPK_MK2_MAPKAPK2_ST	Q6JBY9	RCSD1	P49137	MAPKAPK2	S50	P55S	55	Missense	distal	5	no	12.794	12.712	EPSD	COSMIC	11.681	Down-regulation
CAMK_MAPKAPK_MK2_MAPKAPK2_ST	Q6JBY9	RCSD1	P49137	MAPKAPK2	S105	A104T	104	Missense	proximal	-1	no	12.299	12.291	EPSD	COSMIC	11.681	Down-regulation
CAMK_MAPKAPK_MK2_MAPKAPK2_ST	Q6JBY9	RCSD1	P49137	MAPKAPK2	S105	A104D	104	Missense	proximal	-1	no	12.299	12.308	EPSD	COSMIC	11.681	Up-regulation
CAMK_MAPKAPK_MK2_MAPKAPK2_ST	Q6JBY9	RCSD1	P49137	MAPKAPK2	S120	P117R	117	Missense	distal	-3	no	9.408	14.072	EPSD	COSMIC;GDSC;CCLE	11.681	Gain
CAMK_MAPKAPK_MK2_MAPKAPK2_ST	Q6JBY9	RCSD1	P49137	MAPKAPK2	S179	G182E	182	Missense	distal	3	no	19.154	19.237	PhosphoSitePlus;EPSD	COSMIC	11.681	Up-regulation
CAMK_MAPKAPK_MK2_MAPKAPK2_ST	Q6JBY9	RCSD1	P49137	MAPKAPK2	S179	E183K	183	Missense	distal	4	no	19.154	18.972	PhosphoSitePlus;EPSD	COSMIC	11.681	Down-regulation
CAMK_MAPKAPK_MK2_MAPKAPK2_ST	Q6JBY9	RCSD1	P49137	MAPKAPK2	S179	S179C	179	Missense	central	0	yes	19.154	0.000	PhosphoSitePlus;EPSD	COSMIC	11.681	Loss
CAMK_MAPKAPK_MK2_MAPKAPK2_ST	Q6JBY9	RCSD1	P49137	MAPKAPK2	S211	K210N	210	Missense	proximal	-1	no	13.244	13.248	EPSD	COSMIC	11.681	Up-regulation
CAMK_MAPKAPK_MK2_MAPKAPK2_ST	Q6JBY9	RCSD1	P49137	MAPKAPK2	S211	L207V	207	Missense	distal	-4	no	13.244	13.256	EPSD	COSMIC	11.681	Up-regulation
CAMK_MAPKAPK_MK2_MAPKAPK2_ST	Q6JBY9	RCSD1	P49137	MAPKAPK2	S211	S209C	209	Missense	proximal	-2	no	13.244	9.766	EPSD	COSMIC	11.681	Loss
CAMK_MAPKAPK_MK2_MAPKAPK2_ST	Q6JBY9	RCSD1	P49137	MAPKAPK2	S211	P208L	208	Missense	distal	-3	no	13.244	12.818	EPSD	COSMIC	11.681	Down-regulation
CAMK_MAPKAPK_MK2_MAPKAPK2_ST	Q6JBY9	RCSD1	P49137	MAPKAPK2	S242	K236E	236	Missense	distal	-6	no	11.822	11.759	EPSD	COSMIC	11.681	Down-regulation
CAMK_MAPKAPK_MK2_MAPKAPK2_ST	Q6JBY9	RCSD1	P49137	MAPKAPK2	S242	R241K	241	Missense	proximal	-1	no	11.822	11.843	EPSD	COSMIC;GDSC	11.681	Up-regulation
CAMK_MAPKAPK_MK2_MAPKAPK2_ST	Q6JBY9	RCSD1	P49137	MAPKAPK2	S242	P243L	243	Missense	proximal	1	no	11.822	11.913	EPSD	COSMIC	11.681	Up-regulation
CAMK_MAPKAPK_MK2_MAPKAPK2_ST	Q6JBY9	RCSD1	P49137	MAPKAPK2	S242	E247A	247	Missense	distal	5	no	11.822	11.770	EPSD	COSMIC	11.681	Down-regulation
CAMK_MAPKAPK_MK2_MAPKAPK2_ST	Q6JBY9	RCSD1	P49137	MAPKAPK2	S244	R241K	241	Missense	distal	-3	no	19.793	14.669	EPSD;PhosphoSitePlus	COSMIC;GDSC	11.681	Down-regulation
CAMK_MAPKAPK_MK2_MAPKAPK2_ST	Q6JBY9	RCSD1	P49137	MAPKAPK2	S244	E247A	247	Missense	distal	3	no	19.793	19.855	EPSD;PhosphoSitePlus	COSMIC	11.681	Up-regulation
CAMK_MAPKAPK_MK2_MAPKAPK2_ST	Q6JBY9	RCSD1	P49137	MAPKAPK2	S268	D272N	272	Missense	distal	4	no	16.196	16.197	EPSD	COSMIC	11.681	Up-regulation
CAMK_MAPKAPK_MK2_MAPKAPK2_ST	Q6JBY9	RCSD1	P49137	MAPKAPK2	S268	K263N	263	Missense	distal	-5	no	16.196	16.157	EPSD	COSMIC	11.681	Down-regulation
CAMK_MAPKAPK_MK2_MAPKAPK2_ST	Q6JBY9	RCSD1	P49137	MAPKAPK2	S298	A292V	292	Missense	distal	-6	no	16.417	16.446	EPSD	COSMIC	11.681	Up-regulation
CAMK_MAPKAPK_MK2_MAPKAPK2_ST	Q6JBY9	RCSD1	P49137	MAPKAPK2	S298	E302V	302	Missense	distal	4	no	16.417	16.348	EPSD	COSMIC	11.681	Down-regulation
CAMK_MAPKAPK_MK2_MAPKAPK2_ST	Q6JBY9	RCSD1	P49137	MAPKAPK2	S298	E293K	293	Missense	distal	-5	no	16.417	15.810	EPSD	COSMIC	11.681	Down-regulation
CAMK_MAPKAPK_MK2_MAPKAPK2_ST	Q6JBY9	RCSD1	P49137	MAPKAPK2	S394	P400S	400	Missense	distal	6	no	12.750	12.766	EPSD	COSMIC;GDSC	11.681	Up-regulation
CAMK_MAPKAPK_MK2_MAPKAPK2_ST	Q969V6	MRTFA	P49137	MAPKAPK2	S16	R21W	21	Missense	distal	5	no	11.897	12.116	EPSD	COSMIC	11.681	Up-regulation
CAMK_MAPKAPK_MK2_MAPKAPK2_ST	Q969V6	MRTFA	P49137	MAPKAPK2	S16	R19W	19	Missense	distal	3	no	11.897	11.859	EPSD	COSMIC	11.681	Down-regulation
CAMK_MAPKAPK_MK2_MAPKAPK2_ST	Q969V6	MRTFA	P49137	MAPKAPK2	S16	R21G	21	Missense	distal	5	no	11.897	12.168	EPSD	COSMIC	11.681	Up-regulation
CAMK_MAPKAPK_MK2_MAPKAPK2_ST	Q969V6	MRTFA	P49137	MAPKAPK2	S16	E12D	12	Missense	distal	-4	no	11.897	12.068	EPSD	COSMIC	11.681	Up-regulation
CAMK_MAPKAPK_MK2_MAPKAPK2_ST	Q969V6	MRTFA	P49137	MAPKAPK2	S16	E23D	23	Missense	distal	7	no	11.897	11.708	EPSD	COSMIC	11.681	Down-regulation
CAMK_MAPKAPK_MK2_MAPKAPK2_ST	Q969V6	MRTFA	P49137	MAPKAPK2	S16	S16R	16	Missense	central	0	yes	11.897	0.000	EPSD	COSMIC	11.681	Loss
CAMK_MAPKAPK_MK2_MAPKAPK2_ST	Q969V6	MRTFA	P49137	MAPKAPK2	T22	R21W	21	Missense	proximal	-1	no	14.050	14.068	EPSD	COSMIC	11.681	Up-regulation
CAMK_MAPKAPK_MK2_MAPKAPK2_ST	Q969V6	MRTFA	P49137	MAPKAPK2	T22	R19W	19	Missense	distal	-3	no	14.050	5.471	EPSD	COSMIC	11.681	Loss
CAMK_MAPKAPK_MK2_MAPKAPK2_ST	Q969V6	MRTFA	P49137	MAPKAPK2	T22	R21G	21	Missense	proximal	-1	no	14.050	14.078	EPSD	COSMIC	11.681	Up-regulation
CAMK_MAPKAPK_MK2_MAPKAPK2_ST	Q969V6	MRTFA	P49137	MAPKAPK2	T22	R28Q	28	Missense	distal	6	no	14.050	14.030	EPSD	COSMIC	11.681	Down-regulation
CAMK_MAPKAPK_MK2_MAPKAPK2_ST	Q969V6	MRTFA	P49137	MAPKAPK2	T22	E23D	23	Missense	proximal	1	no	14.050	13.616	EPSD	COSMIC	11.681	Down-regulation
CAMK_MAPKAPK_MK2_MAPKAPK2_ST	Q969V6	MRTFA	P49137	MAPKAPK2	T22	S16R	16	Missense	distal	-6	no	14.050	14.063	EPSD	COSMIC	11.681	Up-regulation
CAMK_MAPKAPK_MK2_MAPKAPK2_ST	Q969V6	MRTFA	P49137	MAPKAPK2	S124	D121N	121	Missense	distal	-3	no	11.233	11.807	EPSD	COSMIC	11.681	Gain
CAMK_MAPKAPK_MK2_MAPKAPK2_ST	Q969V6	MRTFA	P49137	MAPKAPK2	S136	P138L	138	Missense	proximal	2	no	12.858	12.635	EPSD	COSMIC	11.681	Down-regulation
CAMK_MAPKAPK_MK2_MAPKAPK2_ST	Q969V6	MRTFA	P49137	MAPKAPK2	S151	P157H	157	Missense	distal	6	no	12.201	12.184	EPSD	COSMIC	11.681	Down-regulation
CAMK_MAPKAPK_MK2_MAPKAPK2_ST	Q969V6	MRTFA	P49137	MAPKAPK2	S151	S154C	154	Missense	distal	3	no	12.201	12.082	EPSD	COSMIC	11.681	Down-regulation
CAMK_MAPKAPK_MK2_MAPKAPK2_ST	Q969V6	MRTFA	P49137	MAPKAPK2	S151	P157S	157	Missense	distal	6	no	12.201	12.218	EPSD	COSMIC	11.681	Up-regulation
CAMK_MAPKAPK_MK2_MAPKAPK2_ST	Q969V6	MRTFA	P49137	MAPKAPK2	S151	R144G	144	Missense	distal	-7	no	12.201	12.294	EPSD	COSMIC	11.681	Up-regulation
CAMK_MAPKAPK_MK2_MAPKAPK2_ST	Q969V6	MRTFA	P49137	MAPKAPK2	S154	P157H	157	Missense	distal	3	no	12.260	12.061	EPSD	COSMIC	11.681	Down-regulation
CAMK_MAPKAPK_MK2_MAPKAPK2_ST	Q969V6	MRTFA	P49137	MAPKAPK2	S154	S154C	154	Missense	central	0	yes	12.260	0.000	EPSD	COSMIC	11.681	Loss
CAMK_MAPKAPK_MK2_MAPKAPK2_ST	Q969V6	MRTFA	P49137	MAPKAPK2	S154	P157S	157	Missense	distal	3	no	12.260	12.267	EPSD	COSMIC	11.681	Up-regulation
CAMK_MAPKAPK_MK2_MAPKAPK2_ST	Q969V6	MRTFA	P49137	MAPKAPK2	S156	P157H	157	Missense	proximal	1	no	14.894	14.418	EPSD	COSMIC	11.681	Down-regulation
CAMK_MAPKAPK_MK2_MAPKAPK2_ST	Q969V6	MRTFA	P49137	MAPKAPK2	S156	S154C	154	Missense	proximal	-2	no	14.894	11.415	EPSD	COSMIC	11.681	Loss
CAMK_MAPKAPK_MK2_MAPKAPK2_ST	Q969V6	MRTFA	P49137	MAPKAPK2	S156	P157S	157	Missense	proximal	1	no	14.894	14.783	EPSD	COSMIC	11.681	Down-regulation
CAMK_MAPKAPK_MK2_MAPKAPK2_ST	Q969V6	MRTFA	P49137	MAPKAPK2	S156	Q163P	163	Missense	distal	7	no	14.894	15.345	EPSD	COSMIC	11.681	Up-regulation
CAMK_MAPKAPK_MK2_MAPKAPK2_ST	Q969V6	MRTFA	P49137	MAPKAPK2	S203	P205S	205	Missense	proximal	2	no	12.427	12.619	EPSD	COSMIC	11.681	Up-regulation
CAMK_MAPKAPK_MK2_MAPKAPK2_ST	Q969V6	MRTFA	P49137	MAPKAPK2	S203	P205H	205	Missense	proximal	2	no	12.427	12.004	EPSD	COSMIC	11.681	Down-regulation
CAMK_MAPKAPK_MK2_MAPKAPK2_ST	Q969V6	MRTFA	P49137	MAPKAPK2	S203	K202T	202	Missense	proximal	-1	no	12.427	12.412	EPSD	COSMIC	11.681	Down-regulation
CAMK_MAPKAPK_MK2_MAPKAPK2_ST	Q969V6	MRTFA	P49137	MAPKAPK2	S203	K202E	202	Missense	proximal	-1	no	12.427	12.417	EPSD	COSMIC	11.681	Down-regulation
CAMK_MAPKAPK_MK2_MAPKAPK2_ST	Q969V6	MRTFA	P49137	MAPKAPK2	S203	P205L	205	Missense	proximal	2	no	12.427	12.204	EPSD	COSMIC	11.681	Down-regulation
CAMK_MAPKAPK_MK2_MAPKAPK2_ST	Q969V6	MRTFA	P49137	MAPKAPK2	S303	P307S	307	Missense	distal	4	no	11.960	12.019	EPSD	COSMIC	11.681	Up-regulation
CAMK_MAPKAPK_MK2_MAPKAPK2_ST	Q969V6	MRTFA	P49137	MAPKAPK2	S303	R309C	309	Missense	distal	6	no	11.960	11.935	EPSD	COSMIC	11.681	Down-regulation
CAMK_MAPKAPK_MK2_MAPKAPK2_ST	Q969V6	MRTFA	P49137	MAPKAPK2	S303	E298K	298	Missense	distal	-5	no	11.960	11.352	EPSD	COSMIC	11.681	Loss
CAMK_MAPKAPK_MK2_MAPKAPK2_ST	Q969V6	MRTFA	P49137	MAPKAPK2	S303	S302R	302	Missense	proximal	-1	no	11.960	11.950	EPSD	COSMIC	11.681	Down-regulation
CAMK_MAPKAPK_MK2_MAPKAPK2_ST	Q969V6	MRTFA	P49137	MAPKAPK2	S303	S303R	303	Missense	central	0	yes	11.960	0.000	EPSD	COSMIC	11.681	Loss
CAMK_MAPKAPK_MK2_MAPKAPK2_ST	Q969V6	MRTFA	P49137	MAPKAPK2	T305	S302R	302	Missense	distal	-3	no	11.348	17.677	EPSD	COSMIC	11.681	Gain
CAMK_MAPKAPK_MK2_MAPKAPK2_ST	Q969V6	MRTFA	P49137	MAPKAPK2	S310	P307S	307	Missense	distal	-3	no	12.399	10.734	EPSD	COSMIC	11.681	Loss
CAMK_MAPKAPK_MK2_MAPKAPK2_ST	Q969V6	MRTFA	P49137	MAPKAPK2	S310	R309C	309	Missense	proximal	-1	no	12.399	12.420	EPSD	COSMIC	11.681	Up-regulation
CAMK_MAPKAPK_MK2_MAPKAPK2_ST	Q969V6	MRTFA	P49137	MAPKAPK2	S310	S312P	312	Missense	proximal	2	no	12.399	12.207	EPSD	COSMIC	11.681	Down-regulation
CAMK_MAPKAPK_MK2_MAPKAPK2_ST	Q969V6	MRTFA	P49137	MAPKAPK2	S310	S303R	303	Missense	distal	-7	no	12.399	12.365	EPSD	COSMIC	11.681	Down-regulation
CAMK_MAPKAPK_MK2_MAPKAPK2_ST	Q969V6	MRTFA	P49137	MAPKAPK2	S312	S319G	319	Missense	distal	7	no	18.848	18.643	EPSD;PhosphoSitePlus	COSMIC	11.681	Down-regulation
CAMK_MAPKAPK_MK2_MAPKAPK2_ST	Q969V6	MRTFA	P49137	MAPKAPK2	S312	P307S	307	Missense	distal	-5	no	18.848	18.859	EPSD;PhosphoSitePlus	COSMIC	11.681	Up-regulation
CAMK_MAPKAPK_MK2_MAPKAPK2_ST	Q969V6	MRTFA	P49137	MAPKAPK2	S312	R309C	309	Missense	distal	-3	no	18.848	10.449	EPSD;PhosphoSitePlus	COSMIC	11.681	Loss
CAMK_MAPKAPK_MK2_MAPKAPK2_ST	Q969V6	MRTFA	P49137	MAPKAPK2	S312	S312P	312	Missense	central	0	yes	18.848	0.000	EPSD;PhosphoSitePlus	COSMIC	11.681	Loss
CAMK_MAPKAPK_MK2_MAPKAPK2_ST	Q969V6	MRTFA	P49137	MAPKAPK2	T314	S319G	319	Missense	distal	5	no	11.501	11.791	EPSD	COSMIC	11.681	Gain
CAMK_MAPKAPK_MK2_MAPKAPK2_ST	Q969V6	MRTFA	P49137	MAPKAPK2	S316	S319G	319	Missense	distal	3	no	13.071	12.971	EPSD	COSMIC	11.681	Down-regulation
CAMK_MAPKAPK_MK2_MAPKAPK2_ST	Q969V6	MRTFA	P49137	MAPKAPK2	S316	R309C	309	Missense	distal	-7	no	13.071	13.150	EPSD	COSMIC	11.681	Up-regulation
CAMK_MAPKAPK_MK2_MAPKAPK2_ST	Q969V6	MRTFA	P49137	MAPKAPK2	S316	S320L	320	Missense	distal	4	no	13.071	12.918	EPSD	COSMIC	11.681	Down-regulation
CAMK_MAPKAPK_MK2_MAPKAPK2_ST	Q969V6	MRTFA	P49137	MAPKAPK2	S316	S312P	312	Missense	distal	-4	no	13.071	13.150	EPSD	COSMIC	11.681	Up-regulation
CAMK_MAPKAPK_MK2_MAPKAPK2_ST	Q969V6	MRTFA	P49137	MAPKAPK2	S316	S320G	320	Missense	distal	4	no	13.071	12.882	EPSD	COSMIC	11.681	Down-regulation
CAMK_MAPKAPK_MK2_MAPKAPK2_ST	Q969V6	MRTFA	P49137	MAPKAPK2	S318	S319G	319	Missense	proximal	1	no	13.122	12.702	EPSD	COSMIC	11.681	Down-regulation
CAMK_MAPKAPK_MK2_MAPKAPK2_ST	Q969V6	MRTFA	P49137	MAPKAPK2	S318	S320L	320	Missense	proximal	2	no	13.122	12.707	EPSD	COSMIC	11.681	Down-regulation
CAMK_MAPKAPK_MK2_MAPKAPK2_ST	Q969V6	MRTFA	P49137	MAPKAPK2	S318	S320G	320	Missense	proximal	2	no	13.122	12.687	EPSD	COSMIC	11.681	Down-regulation
CAMK_MAPKAPK_MK2_MAPKAPK2_ST	Q969V6	MRTFA	P49137	MAPKAPK2	S319	S319G	319	Missense	central	0	yes	14.066	0.000	EPSD	COSMIC	11.681	Loss
CAMK_MAPKAPK_MK2_MAPKAPK2_ST	Q969V6	MRTFA	P49137	MAPKAPK2	S319	S320L	320	Missense	proximal	1	no	14.066	14.267	EPSD	COSMIC	11.681	Up-regulation
CAMK_MAPKAPK_MK2_MAPKAPK2_ST	Q969V6	MRTFA	P49137	MAPKAPK2	S319	S312P	312	Missense	distal	-7	no	14.066	14.064	EPSD	COSMIC	11.681	Down-regulation
CAMK_MAPKAPK_MK2_MAPKAPK2_ST	Q969V6	MRTFA	P49137	MAPKAPK2	S319	S320G	320	Missense	proximal	1	no	14.066	13.646	EPSD	COSMIC	11.681	Down-regulation
CAMK_MAPKAPK_MK2_MAPKAPK2_ST	Q969V6	MRTFA	P49137	MAPKAPK2	S320	S319G	319	Missense	proximal	-1	no	12.164	12.182	EPSD	COSMIC	11.681	Up-regulation
CAMK_MAPKAPK_MK2_MAPKAPK2_ST	Q969V6	MRTFA	P49137	MAPKAPK2	S320	G327W	327	Missense	distal	7	no	12.164	12.125	EPSD	COSMIC	11.681	Down-regulation
CAMK_MAPKAPK_MK2_MAPKAPK2_ST	Q969V6	MRTFA	P49137	MAPKAPK2	S320	S320L	320	Missense	central	0	yes	12.164	0.000	EPSD	COSMIC	11.681	Loss
CAMK_MAPKAPK_MK2_MAPKAPK2_ST	Q969V6	MRTFA	P49137	MAPKAPK2	S320	S320G	320	Missense	central	0	yes	12.164	0.000	EPSD	COSMIC	11.681	Loss
CAMK_MAPKAPK_MK2_MAPKAPK2_ST	Q969V6	MRTFA	P49137	MAPKAPK2	S333	L328I	328	Missense	distal	-5	no	20.573	20.385	PhosphoSitePlus;EPSD	COSMIC	11.681	Down-regulation
CAMK_MAPKAPK_MK2_MAPKAPK2_ST	Q969V6	MRTFA	P49137	MAPKAPK2	S333	G327W	327	Missense	distal	-6	no	20.573	20.547	PhosphoSitePlus;EPSD	COSMIC	11.681	Down-regulation
CAMK_MAPKAPK_MK2_MAPKAPK2_ST	Q969V6	MRTFA	P49137	MAPKAPK2	S333	R330H	330	Missense	distal	-3	no	20.573	15.814	PhosphoSitePlus;EPSD	COSMIC	11.681	Down-regulation
CAMK_MAPKAPK_MK2_MAPKAPK2_ST	Q969V6	MRTFA	P49137	MAPKAPK2	S333	R330C	330	Missense	distal	-3	no	20.573	12.174	PhosphoSitePlus;EPSD	COSMIC	11.681	Down-regulation
CAMK_MAPKAPK_MK2_MAPKAPK2_ST	Q969V6	MRTFA	P49137	MAPKAPK2	S335	R330H	330	Missense	distal	-5	no	12.252	11.775	EPSD	COSMIC	11.681	Down-regulation
CAMK_MAPKAPK_MK2_MAPKAPK2_ST	Q969V6	MRTFA	P49137	MAPKAPK2	S335	A342T	342	Missense	distal	7	no	12.252	12.354	EPSD	COSMIC	11.681	Up-regulation
CAMK_MAPKAPK_MK2_MAPKAPK2_ST	Q969V6	MRTFA	P49137	MAPKAPK2	S335	R330C	330	Missense	distal	-5	no	12.252	11.648	EPSD	COSMIC	11.681	Loss
CAMK_MAPKAPK_MK2_MAPKAPK2_ST	Q969V6	MRTFA	P49137	MAPKAPK2	T417	G418A	418	Missense	proximal	1	no	11.535	11.895	EPSD	COSMIC	11.681	Gain
CAMK_MAPKAPK_MK2_MAPKAPK2_ST	Q969V6	MRTFA	P49137	MAPKAPK2	S449	G448S	448	Missense	proximal	-1	no	12.491	12.474	EPSD	COSMIC	11.681	Down-regulation
CAMK_MAPKAPK_MK2_MAPKAPK2_ST	Q969V6	MRTFA	P49137	MAPKAPK2	S449	P451S	451	Missense	proximal	2	no	12.491	12.683	EPSD	COSMIC	11.681	Up-regulation
CAMK_MAPKAPK_MK2_MAPKAPK2_ST	Q969V6	MRTFA	P49137	MAPKAPK2	S449	T447M	447	Missense	proximal	-2	no	12.491	12.120	EPSD	COSMIC	11.681	Down-regulation
CAMK_MAPKAPK_MK2_MAPKAPK2_ST	Q969V6	MRTFA	P49137	MAPKAPK2	S449	V442G	442	Missense	distal	-7	no	12.491	12.514	EPSD	COSMIC	11.681	Up-regulation
CAMK_MAPKAPK_MK2_MAPKAPK2_ST	Q969V6	MRTFA	P49137	MAPKAPK2	S449	P452S	452	Missense	distal	3	no	12.491	12.498	EPSD	COSMIC	11.681	Up-regulation
CAMK_MAPKAPK_MK2_MAPKAPK2_ST	Q969V6	MRTFA	P49137	MAPKAPK2	S454	P452S	452	Missense	proximal	-2	no	10.483	13.714	EPSD	COSMIC	11.681	Gain
CAMK_MAPKAPK_MK2_MAPKAPK2_ST	Q969V6	MRTFA	P49137	MAPKAPK2	S458	P457S	457	Missense	proximal	-1	no	13.699	13.698	EPSD	COSMIC	11.681	Down-regulation
CAMK_MAPKAPK_MK2_MAPKAPK2_ST	Q969V6	MRTFA	P49137	MAPKAPK2	S458	R460H	460	Missense	proximal	2	no	13.699	13.189	EPSD	COSMIC	11.681	Down-regulation
CAMK_MAPKAPK_MK2_MAPKAPK2_ST	Q969V6	MRTFA	P49137	MAPKAPK2	S458	P451S	451	Missense	distal	-7	no	13.699	13.702	EPSD	COSMIC	11.681	Up-regulation
CAMK_MAPKAPK_MK2_MAPKAPK2_ST	Q969V6	MRTFA	P49137	MAPKAPK2	S458	R460L	460	Missense	proximal	2	no	13.699	13.389	EPSD	COSMIC	11.681	Down-regulation
CAMK_MAPKAPK_MK2_MAPKAPK2_ST	Q969V6	MRTFA	P49137	MAPKAPK2	S507	P512H	512	Missense	distal	5	no	14.884	15.126	EPSD	COSMIC	11.681	Up-regulation
CAMK_MAPKAPK_MK2_MAPKAPK2_ST	Q969V6	MRTFA	P49137	MAPKAPK2	S507	G502D	502	Missense	distal	-5	no	14.884	14.988	EPSD	COSMIC	11.681	Up-regulation
CAMK_MAPKAPK_MK2_MAPKAPK2_ST	Q969V6	MRTFA	P49137	MAPKAPK2	S507	G513E	513	Missense	distal	6	no	14.884	14.899	EPSD	COSMIC	11.681	Up-regulation
CAMK_MAPKAPK_MK2_MAPKAPK2_ST	Q969V6	MRTFA	P49137	MAPKAPK2	S507	P512S	512	Missense	distal	5	no	14.884	14.801	EPSD	COSMIC	11.681	Down-regulation
CAMK_MAPKAPK_MK2_MAPKAPK2_ST	Q969V6	MRTFA	P49137	MAPKAPK2	S507	C509Y	509	Missense	proximal	2	no	14.884	14.594	EPSD	COSMIC	11.681	Down-regulation
CAMK_MAPKAPK_MK2_MAPKAPK2_ST	Q969V6	MRTFA	P49137	MAPKAPK2	S507	R504L	504	Missense	distal	-3	no	14.884	9.794	EPSD	COSMIC	11.681	Loss
CAMK_MAPKAPK_MK2_MAPKAPK2_ST	Q969V6	MRTFA	P49137	MAPKAPK2	S507	G514E	514	Missense	distal	7	no	14.884	15.166	EPSD	COSMIC	11.681	Up-regulation
CAMK_MAPKAPK_MK2_MAPKAPK2_ST	Q969V6	MRTFA	P49137	MAPKAPK2	S690	S695L	695	Missense	distal	5	no	11.869	12.039	EPSD	COSMIC	11.681	Up-regulation
CAMK_MAPKAPK_MK2_MAPKAPK2_ST	Q969V6	MRTFA	P49137	MAPKAPK2	S690	S683C	683	Missense	distal	-7	no	11.869	11.914	EPSD	COSMIC	11.681	Up-regulation
CAMK_MAPKAPK_MK2_MAPKAPK2_ST	Q969V6	MRTFA	P49137	MAPKAPK2	S690	S683P	683	Missense	distal	-7	no	11.869	11.867	EPSD	COSMIC	11.681	Down-regulation
CAMK_MAPKAPK_MK2_MAPKAPK2_ST	Q969V6	MRTFA	P49137	MAPKAPK2	S690	S683Y	683	Missense	distal	-7	no	11.869	11.945	EPSD	COSMIC	11.681	Up-regulation
CAMK_MAPKAPK_MK2_MAPKAPK2_ST	Q969V6	MRTFA	P49137	MAPKAPK2	S690	S695I	695	Missense	distal	5	no	11.869	12.073	EPSD	COSMIC	11.681	Up-regulation
CAMK_MAPKAPK_MK2_MAPKAPK2_ST	Q969V6	MRTFA	P49137	MAPKAPK2	S690	S683G	683	Missense	distal	-7	no	11.869	11.927	EPSD	COSMIC	11.681	Up-regulation
CAMK_MAPKAPK_MK2_MAPKAPK2_ST	Q969V6	MRTFA	P49137	MAPKAPK2	S695	S695L	695	Missense	central	0	yes	12.052	0.000	EPSD	COSMIC	11.681	Loss
CAMK_MAPKAPK_MK2_MAPKAPK2_ST	Q969V6	MRTFA	P49137	MAPKAPK2	S695	A699V	699	Missense	distal	4	no	12.052	11.901	EPSD	COSMIC	11.681	Down-regulation
CAMK_MAPKAPK_MK2_MAPKAPK2_ST	Q969V6	MRTFA	P49137	MAPKAPK2	S695	P698R	698	Missense	distal	3	no	12.052	11.989	EPSD	COSMIC	11.681	Down-regulation
CAMK_MAPKAPK_MK2_MAPKAPK2_ST	Q969V6	MRTFA	P49137	MAPKAPK2	S695	S701F	701	Missense	distal	6	no	12.052	12.007	EPSD	COSMIC	11.681	Down-regulation
CAMK_MAPKAPK_MK2_MAPKAPK2_ST	Q969V6	MRTFA	P49137	MAPKAPK2	S695	A702G	702	Missense	distal	7	no	12.052	11.646	EPSD	COSMIC	11.681	Loss
CAMK_MAPKAPK_MK2_MAPKAPK2_ST	Q969V6	MRTFA	P49137	MAPKAPK2	S695	S695I	695	Missense	central	0	yes	12.052	0.000	EPSD	COSMIC	11.681	Loss
CAMK_MAPKAPK_MK2_MAPKAPK2_ST	Q969V6	MRTFA	P49137	MAPKAPK2	S733	A731T	731	Missense	proximal	-2	no	12.082	11.923	EPSD	COSMIC	11.681	Down-regulation
CAMK_MAPKAPK_MK2_MAPKAPK2_ST	Q969V6	MRTFA	P49137	MAPKAPK2	S733	Q734K	734	Missense	proximal	1	no	12.082	12.130	EPSD	COSMIC	11.681	Up-regulation
CAMK_MAPKAPK_MK2_MAPKAPK2_ST	Q969V6	MRTFA	P49137	MAPKAPK2	S733	P726L	726	Missense	distal	-7	no	12.082	12.116	EPSD	COSMIC	11.681	Up-regulation
CAMK_MAPKAPK_MK2_MAPKAPK2_ST	Q969V6	MRTFA	P49137	MAPKAPK2	S733	P726S	726	Missense	distal	-7	no	12.082	12.084	EPSD	COSMIC	11.681	Up-regulation
CAMK_MAPKAPK_MK2_MAPKAPK2_ST	Q969V6	MRTFA	P49137	MAPKAPK2	S733	Q735K	735	Missense	proximal	2	no	12.082	11.984	EPSD	COSMIC	11.681	Down-regulation
CAMK_MAPKAPK_MK2_MAPKAPK2_ST	Q969V6	MRTFA	P49137	MAPKAPK2	S807	P805A	805	Missense	proximal	-2	no	11.343	12.979	EPSD	COSMIC	11.681	Gain
CAMK_MAPKAPK_MK2_MAPKAPK2_ST	Q969V6	MRTFA	P49137	MAPKAPK2	S859	S859P	859	Missense	central	0	yes	12.286	0.000	EPSD	COSMIC	11.681	Loss
CAMK_MAPKAPK_MK2_MAPKAPK2_ST	Q969V6	MRTFA	P49137	MAPKAPK2	S859	H856R	856	Missense	distal	-3	no	12.286	17.046	EPSD	COSMIC	11.681	Up-regulation
CAMK_MAPKAPK_MK2_MAPKAPK2_ST	Q969V6	MRTFA	P49137	MAPKAPK2	S859	I853V	853	Missense	distal	-6	no	12.286	12.292	EPSD	COSMIC	11.681	Up-regulation
CAMK_MAPKAPK_MK2_MAPKAPK2_ST	P63104	YWHAZ	P49137	MAPKAPK2	S58	R55C	55	Missense	distal	-3	no	17.304	8.904	PhosphoSitePlus	COSMIC	11.681	Loss
CAMK_MAPKAPK_MK2_MAPKAPK2_ST	Q9UKV8	AGO2	P49137	MAPKAPK2	S153	P155S	155	Missense	proximal	2	no	15.685	15.877	EPSD	COSMIC	11.681	Up-regulation
CAMK_MAPKAPK_MK2_MAPKAPK2_ST	Q9UKV8	AGO2	P49137	MAPKAPK2	S387	Y393H	393	Missense	distal	6	no	18.966	18.973	PhosphoSitePlus	COSMIC	11.681	Up-regulation
CAMK_MAPKAPK_MK2_MAPKAPK2_ST	Q9UKV8	AGO2	P49137	MAPKAPK2	S798	P802Q	802	Missense	distal	4	no	17.334	17.192	EPSD	COSMIC	11.681	Down-regulation
CAMK_MAPKAPK_MK2_MAPKAPK2_ST	Q00987	MDM2	P49137	MAPKAPK2	S40	G42A	42	Missense	proximal	2	no	12.898	13.303	EPSD	COSMIC	11.681	Up-regulation
CAMK_MAPKAPK_MK2_MAPKAPK2_ST	Q00987	MDM2	P49137	MAPKAPK2	S40	S40L	40	Missense	central	0	yes	12.898	0.000	EPSD	COSMIC	11.681	Loss
CAMK_MAPKAPK_MK2_MAPKAPK2_ST	Q00987	MDM2	P49137	MAPKAPK2	S40	A43E	43	Missense	distal	3	no	12.898	12.836	EPSD	COSMIC	11.681	Down-regulation
CAMK_MAPKAPK_MK2_MAPKAPK2_ST	Q00987	MDM2	P49137	MAPKAPK2	S40	G42C	42	Missense	proximal	2	no	12.898	12.932	EPSD	COSMIC	11.681	Up-regulation
CAMK_MAPKAPK_MK2_MAPKAPK2_ST	Q00987	MDM2	P49137	MAPKAPK2	S40	Q44K	44	Missense	distal	4	no	12.898	12.858	EPSD	COSMIC	11.681	Down-regulation
CAMK_MAPKAPK_MK2_MAPKAPK2_ST	Q00987	MDM2	P49137	MAPKAPK2	S40	L35F	35	Missense	distal	-5	no	12.898	12.200	EPSD	COSMIC	11.681	Down-regulation
CAMK_MAPKAPK_MK2_MAPKAPK2_ST	Q00987	MDM2	P49137	MAPKAPK2	S40	K45Q	45	Missense	distal	5	no	12.898	12.830	EPSD	COSMIC;CCLE	11.681	Down-regulation
CAMK_MAPKAPK_MK2_MAPKAPK2_ST	Q00987	MDM2	P49137	MAPKAPK2	S118	E114D	114	Missense	distal	-4	no	12.261	12.433	EPSD	COSMIC	11.681	Up-regulation
CAMK_MAPKAPK_MK2_MAPKAPK2_ST	Q00987	MDM2	P49137	MAPKAPK2	S118	D117N	117	Missense	proximal	-1	no	12.261	12.263	EPSD	COSMIC	11.681	Up-regulation
CAMK_MAPKAPK_MK2_MAPKAPK2_ST	Q00987	MDM2	P49137	MAPKAPK2	S118	E124K	124	Missense	distal	6	no	12.261	12.247	EPSD	COSMIC	11.681	Down-regulation
CAMK_MAPKAPK_MK2_MAPKAPK2_ST	Q00987	MDM2	P49137	MAPKAPK2	S118	S121F	121	Missense	distal	3	no	12.261	12.049	EPSD	COSMIC	11.681	Down-regulation
CAMK_MAPKAPK_MK2_MAPKAPK2_ST	Q00987	MDM2	P49137	MAPKAPK2	S157	P156R	156	Missense	proximal	-1	no	12.807	12.797	PhosphoSitePlus;EPSD	COSMIC	11.681	Down-regulation
CAMK_MAPKAPK_MK2_MAPKAPK2_ST	Q00987	MDM2	P49137	MAPKAPK2	S157	R155T	155	Missense	proximal	-2	no	12.807	13.320	PhosphoSitePlus;EPSD	COSMIC	11.681	Up-regulation
CAMK_MAPKAPK_MK2_MAPKAPK2_ST	Q00987	MDM2	P49137	MAPKAPK2	S157	S160F	160	Missense	distal	3	no	12.807	12.596	PhosphoSitePlus;EPSD	COSMIC	11.681	Down-regulation
CAMK_MAPKAPK_MK2_MAPKAPK2_ST	Q00987	MDM2	P49137	MAPKAPK2	S157	H151Y	151	Missense	distal	-6	no	12.807	12.834	PhosphoSitePlus;EPSD	COSMIC	11.681	Up-regulation
CAMK_MAPKAPK_MK2_MAPKAPK2_ST	Q00987	MDM2	P49137	MAPKAPK2	S157	P156S	156	Missense	proximal	-1	no	12.807	12.806	PhosphoSitePlus;EPSD	COSMIC	11.681	Down-regulation
CAMK_MAPKAPK_MK2_MAPKAPK2_ST	Q00987	MDM2	P49137	MAPKAPK2	S157	S159R	159	Missense	proximal	2	no	12.807	12.703	PhosphoSitePlus;EPSD	COSMIC	11.681	Down-regulation
CAMK_MAPKAPK_MK2_MAPKAPK2_ST	Q00987	MDM2	P49137	MAPKAPK2	S157	S159G	159	Missense	proximal	2	no	12.807	12.373	PhosphoSitePlus;EPSD	COSMIC	11.681	Down-regulation
CAMK_MAPKAPK_MK2_MAPKAPK2_ST	Q00987	MDM2	P49137	MAPKAPK2	S157	S159N	159	Missense	proximal	2	no	12.807	12.392	PhosphoSitePlus;EPSD	COSMIC	11.681	Down-regulation
CAMK_MAPKAPK_MK2_MAPKAPK2_ST	Q00987	MDM2	P49137	MAPKAPK2	S157	R161T	161	Missense	distal	4	no	12.807	12.920	PhosphoSitePlus;EPSD	COSMIC	11.681	Up-regulation
CAMK_MAPKAPK_MK2_MAPKAPK2_ST	Q00987	MDM2	P49137	MAPKAPK2	T158	P156R	156	Missense	proximal	-2	no	13.252	14.216	EPSD	COSMIC	11.681	Up-regulation
CAMK_MAPKAPK_MK2_MAPKAPK2_ST	Q00987	MDM2	P49137	MAPKAPK2	T158	R155T	155	Missense	distal	-3	no	13.252	7.376	EPSD	COSMIC	11.681	Loss
CAMK_MAPKAPK_MK2_MAPKAPK2_ST	Q00987	MDM2	P49137	MAPKAPK2	T158	S160F	160	Missense	proximal	2	no	13.252	12.537	EPSD	COSMIC	11.681	Down-regulation
CAMK_MAPKAPK_MK2_MAPKAPK2_ST	Q00987	MDM2	P49137	MAPKAPK2	T158	H151Y	151	Missense	distal	-7	no	13.252	13.271	EPSD	COSMIC	11.681	Up-regulation
CAMK_MAPKAPK_MK2_MAPKAPK2_ST	Q00987	MDM2	P49137	MAPKAPK2	T158	P156S	156	Missense	proximal	-2	no	13.252	16.483	EPSD	COSMIC	11.681	Up-regulation
CAMK_MAPKAPK_MK2_MAPKAPK2_ST	Q00987	MDM2	P49137	MAPKAPK2	T158	S159R	159	Missense	proximal	1	no	13.252	13.275	EPSD	COSMIC	11.681	Up-regulation
CAMK_MAPKAPK_MK2_MAPKAPK2_ST	Q00987	MDM2	P49137	MAPKAPK2	T158	S159G	159	Missense	proximal	1	no	13.252	12.832	EPSD	COSMIC	11.681	Down-regulation
CAMK_MAPKAPK_MK2_MAPKAPK2_ST	Q00987	MDM2	P49137	MAPKAPK2	T158	S159N	159	Missense	proximal	1	no	13.252	12.769	EPSD	COSMIC	11.681	Down-regulation
CAMK_MAPKAPK_MK2_MAPKAPK2_ST	Q00987	MDM2	P49137	MAPKAPK2	T158	R161T	161	Missense	distal	3	no	13.252	13.393	EPSD	COSMIC	11.681	Up-regulation
CAMK_MAPKAPK_MK2_MAPKAPK2_ST	Q00987	MDM2	P49137	MAPKAPK2	S160	P156R	156	Missense	distal	-4	no	12.455	12.386	EPSD	COSMIC	11.681	Down-regulation
CAMK_MAPKAPK_MK2_MAPKAPK2_ST	Q00987	MDM2	P49137	MAPKAPK2	S160	R155T	155	Missense	distal	-5	no	12.455	12.220	EPSD	COSMIC	11.681	Down-regulation
CAMK_MAPKAPK_MK2_MAPKAPK2_ST	Q00987	MDM2	P49137	MAPKAPK2	S160	S160F	160	Missense	central	0	yes	12.455	0.000	EPSD	COSMIC	11.681	Loss
CAMK_MAPKAPK_MK2_MAPKAPK2_ST	Q00987	MDM2	P49137	MAPKAPK2	S160	P156S	156	Missense	distal	-4	no	12.455	12.375	EPSD	COSMIC	11.681	Down-regulation
CAMK_MAPKAPK_MK2_MAPKAPK2_ST	Q00987	MDM2	P49137	MAPKAPK2	S160	S159R	159	Missense	proximal	-1	no	12.455	12.445	EPSD	COSMIC	11.681	Down-regulation
CAMK_MAPKAPK_MK2_MAPKAPK2_ST	Q00987	MDM2	P49137	MAPKAPK2	S160	S159G	159	Missense	proximal	-1	no	12.455	12.473	EPSD	COSMIC	11.681	Up-regulation
CAMK_MAPKAPK_MK2_MAPKAPK2_ST	Q00987	MDM2	P49137	MAPKAPK2	S160	S166C	166	Missense	distal	6	no	12.455	12.427	EPSD	COSMIC	11.681	Down-regulation
CAMK_MAPKAPK_MK2_MAPKAPK2_ST	Q00987	MDM2	P49137	MAPKAPK2	S160	E167Q	167	Missense	distal	7	no	12.455	12.043	EPSD	COSMIC	11.681	Down-regulation
CAMK_MAPKAPK_MK2_MAPKAPK2_ST	Q00987	MDM2	P49137	MAPKAPK2	S160	S159N	159	Missense	proximal	-1	no	12.455	12.470	EPSD	COSMIC	11.681	Up-regulation
CAMK_MAPKAPK_MK2_MAPKAPK2_ST	Q00987	MDM2	P49137	MAPKAPK2	S160	R161T	161	Missense	proximal	1	no	12.455	12.577	EPSD	COSMIC	11.681	Up-regulation
CAMK_MAPKAPK_MK2_MAPKAPK2_ST	Q00987	MDM2	P49137	MAPKAPK2	S160	S166F	166	Missense	distal	6	no	12.455	12.410	EPSD	COSMIC	11.681	Down-regulation
CAMK_MAPKAPK_MK2_MAPKAPK2_ST	Q00987	MDM2	P49137	MAPKAPK2	S166	E170D	170	Missense	distal	4	no	20.101	19.965	EPSD;PhosphoSitePlus	COSMIC	11.681	Down-regulation
CAMK_MAPKAPK_MK2_MAPKAPK2_ST	Q00987	MDM2	P49137	MAPKAPK2	S166	S160F	160	Missense	distal	-6	no	20.101	20.210	EPSD;PhosphoSitePlus	COSMIC	11.681	Up-regulation
CAMK_MAPKAPK_MK2_MAPKAPK2_ST	Q00987	MDM2	P49137	MAPKAPK2	S166	S159R	159	Missense	distal	-7	no	20.101	20.067	EPSD;PhosphoSitePlus	COSMIC	11.681	Down-regulation
CAMK_MAPKAPK_MK2_MAPKAPK2_ST	Q00987	MDM2	P49137	MAPKAPK2	S166	S159G	159	Missense	distal	-7	no	20.101	20.159	EPSD;PhosphoSitePlus	COSMIC	11.681	Up-regulation
CAMK_MAPKAPK_MK2_MAPKAPK2_ST	Q00987	MDM2	P49137	MAPKAPK2	S166	D173Y	173	Missense	distal	7	no	20.101	19.718	EPSD;PhosphoSitePlus	COSMIC	11.681	Down-regulation
CAMK_MAPKAPK_MK2_MAPKAPK2_ST	Q00987	MDM2	P49137	MAPKAPK2	S166	S166C	166	Missense	central	0	yes	20.101	0.000	EPSD;PhosphoSitePlus	COSMIC	11.681	Loss
CAMK_MAPKAPK_MK2_MAPKAPK2_ST	Q00987	MDM2	P49137	MAPKAPK2	S166	E167Q	167	Missense	proximal	1	no	20.101	19.588	EPSD;PhosphoSitePlus	COSMIC	11.681	Down-regulation
CAMK_MAPKAPK_MK2_MAPKAPK2_ST	Q00987	MDM2	P49137	MAPKAPK2	S166	S159N	159	Missense	distal	-7	no	20.101	20.151	EPSD;PhosphoSitePlus	COSMIC	11.681	Up-regulation
CAMK_MAPKAPK_MK2_MAPKAPK2_ST	Q00987	MDM2	P49137	MAPKAPK2	S166	R161T	161	Missense	distal	-5	no	20.101	19.867	EPSD;PhosphoSitePlus	COSMIC	11.681	Down-regulation
CAMK_MAPKAPK_MK2_MAPKAPK2_ST	Q00987	MDM2	P49137	MAPKAPK2	S166	S166F	166	Missense	central	0	yes	20.101	0.000	EPSD;PhosphoSitePlus	COSMIC	11.681	Loss
CAMK_MAPKAPK_MK2_MAPKAPK2_ST	Q00987	MDM2	P49137	MAPKAPK2	S172	E170D	170	Missense	proximal	-2	no	11.961	11.045	EPSD	COSMIC	11.681	Loss
CAMK_MAPKAPK_MK2_MAPKAPK2_ST	Q00987	MDM2	P49137	MAPKAPK2	S172	E178K	178	Missense	distal	6	no	11.961	11.946	EPSD	COSMIC	11.681	Down-regulation
CAMK_MAPKAPK_MK2_MAPKAPK2_ST	Q00987	MDM2	P49137	MAPKAPK2	S172	S176F	176	Missense	distal	4	no	11.961	11.650	EPSD	COSMIC	11.681	Loss
CAMK_MAPKAPK_MK2_MAPKAPK2_ST	Q00987	MDM2	P49137	MAPKAPK2	S172	G177D	177	Missense	distal	5	no	11.961	11.944	EPSD	COSMIC	11.681	Down-regulation
CAMK_MAPKAPK_MK2_MAPKAPK2_ST	Q00987	MDM2	P49137	MAPKAPK2	S172	R179P	179	Missense	distal	7	no	11.961	12.049	EPSD	COSMIC	11.681	Up-regulation
CAMK_MAPKAPK_MK2_MAPKAPK2_ST	Q00987	MDM2	P49137	MAPKAPK2	S172	D173Y	173	Missense	proximal	1	no	11.961	11.757	EPSD	COSMIC	11.681	Down-regulation
CAMK_MAPKAPK_MK2_MAPKAPK2_ST	Q00987	MDM2	P49137	MAPKAPK2	S172	S166C	166	Missense	distal	-6	no	11.961	12.023	EPSD	COSMIC	11.681	Up-regulation
CAMK_MAPKAPK_MK2_MAPKAPK2_ST	Q00987	MDM2	P49137	MAPKAPK2	S172	E167Q	167	Missense	distal	-5	no	11.961	11.447	EPSD	COSMIC	11.681	Loss
CAMK_MAPKAPK_MK2_MAPKAPK2_ST	Q00987	MDM2	P49137	MAPKAPK2	S172	S166F	166	Missense	distal	-6	no	11.961	12.069	EPSD	COSMIC	11.681	Up-regulation
CAMK_MAPKAPK_MK2_MAPKAPK2_ST	Q00987	MDM2	P49137	MAPKAPK2	S186	R183H	183	Missense	distal	-3	no	14.192	9.433	EPSD	COSMIC	11.681	Loss
CAMK_MAPKAPK_MK2_MAPKAPK2_ST	Q00987	MDM2	P49137	MAPKAPK2	S186	I189V	189	Missense	distal	3	no	14.192	14.242	EPSD	COSMIC	11.681	Up-regulation
CAMK_MAPKAPK_MK2_MAPKAPK2_ST	Q00987	MDM2	P49137	MAPKAPK2	S186	K185R	185	Missense	proximal	-1	no	14.192	14.171	EPSD	COSMIC	11.681	Down-regulation
CAMK_MAPKAPK_MK2_MAPKAPK2_ST	Q00987	MDM2	P49137	MAPKAPK2	S186	S190F	190	Missense	distal	4	no	14.192	13.881	EPSD	COSMIC	11.681	Down-regulation
CAMK_MAPKAPK_MK2_MAPKAPK2_ST	Q00987	MDM2	P49137	MAPKAPK2	S186	R183C	183	Missense	distal	-3	no	14.192	5.792	EPSD	COSMIC	11.681	Loss
CAMK_MAPKAPK_MK2_MAPKAPK2_ST	Q00987	MDM2	P49137	MAPKAPK2	S186	R179P	179	Missense	distal	-7	no	14.192	14.224	EPSD	COSMIC	11.681	Up-regulation
CAMK_MAPKAPK_MK2_MAPKAPK2_ST	Q00987	MDM2	P49137	MAPKAPK2	S188	R183H	183	Missense	distal	-5	no	14.269	13.792	EPSD	COSMIC	11.681	Down-regulation
CAMK_MAPKAPK_MK2_MAPKAPK2_ST	Q00987	MDM2	P49137	MAPKAPK2	S188	I189V	189	Missense	proximal	1	no	14.269	14.361	EPSD	COSMIC	11.681	Up-regulation
CAMK_MAPKAPK_MK2_MAPKAPK2_ST	Q00987	MDM2	P49137	MAPKAPK2	S188	K185R	185	Missense	distal	-3	no	14.269	19.393	EPSD	COSMIC	11.681	Up-regulation
CAMK_MAPKAPK_MK2_MAPKAPK2_ST	Q00987	MDM2	P49137	MAPKAPK2	S188	S190F	190	Missense	proximal	2	no	14.269	13.554	EPSD	COSMIC	11.681	Down-regulation
CAMK_MAPKAPK_MK2_MAPKAPK2_ST	Q00987	MDM2	P49137	MAPKAPK2	S188	R183C	183	Missense	distal	-5	no	14.269	13.664	EPSD	COSMIC	11.681	Down-regulation
CAMK_MAPKAPK_MK2_MAPKAPK2_ST	Q00987	MDM2	P49137	MAPKAPK2	S190	K185R	185	Missense	distal	-5	no	11.264	12.076	EPSD	COSMIC	11.681	Gain
CAMK_MAPKAPK_MK2_MAPKAPK2_ST	Q00987	MDM2	P49137	MAPKAPK2	S192	L199P	199	Missense	distal	7	no	11.511	11.985	EPSD	COSMIC	11.681	Gain
CAMK_MAPKAPK_MK2_MAPKAPK2_ST	Q00987	MDM2	P49137	MAPKAPK2	S262	L261R	261	Missense	proximal	-1	no	12.611	12.601	EPSD	COSMIC	11.681	Down-regulation
CAMK_MAPKAPK_MK2_MAPKAPK2_ST	Q00987	MDM2	P49137	MAPKAPK2	S262	E257K	257	Missense	distal	-5	no	12.611	12.003	EPSD	COSMIC	11.681	Down-regulation
CAMK_MAPKAPK_MK2_MAPKAPK2_ST	Q00987	MDM2	P49137	MAPKAPK2	S262	S262N	262	Missense	central	0	yes	12.611	0.000	EPSD	COSMIC	11.681	Loss
CAMK_MAPKAPK_MK2_MAPKAPK2_ST	Q00987	MDM2	P49137	MAPKAPK2	S262	D255N	255	Missense	distal	-7	no	12.611	12.621	EPSD	COSMIC	11.681	Up-regulation
CAMK_MAPKAPK_MK2_MAPKAPK2_ST	Q00987	MDM2	P49137	MAPKAPK2	S262	G265E	265	Missense	distal	3	no	12.611	12.694	EPSD	COSMIC	11.681	Up-regulation
CAMK_MAPKAPK_MK2_MAPKAPK2_ST	Q00987	MDM2	P49137	MAPKAPK2	S262	E263K	263	Missense	proximal	1	no	12.611	12.146	EPSD	COSMIC	11.681	Down-regulation
CAMK_MAPKAPK_MK2_MAPKAPK2_ST	Q9Y580	RBM7	P49137	MAPKAPK2	S88	D94A	94	Missense	distal	6	no	15.964	15.985	EPSD	COSMIC	11.681	Up-regulation
CAMK_MAPKAPK_MK2_MAPKAPK2_ST	Q9Y580	RBM7	P49137	MAPKAPK2	S96	D94A	94	Missense	proximal	-2	no	9.157	11.922	EPSD	COSMIC	11.681	Gain
CAMK_MAPKAPK_MK2_MAPKAPK2_ST	Q9Y580	RBM7	P49137	MAPKAPK2	S113	R119K	119	Missense	distal	6	no	13.214	13.186	EPSD	COSMIC	11.681	Down-regulation
CAMK_MAPKAPK_MK2_MAPKAPK2_ST	Q9Y580	RBM7	P49137	MAPKAPK2	S115	R119K	119	Missense	distal	4	no	11.996	11.821	EPSD	COSMIC	11.681	Down-regulation
CAMK_MAPKAPK_MK2_MAPKAPK2_ST	Q9Y580	RBM7	P49137	MAPKAPK2	S127	M124I	124	Missense	distal	-3	no	10.038	13.140	EPSD	COSMIC;GDSC;CCLE	11.681	Gain
CAMK_MAPKAPK_MK2_MAPKAPK2_ST	Q9Y580	RBM7	P49137	MAPKAPK2	S136	I131V	131	Missense	distal	-5	no	19.857	19.737	EPSD;PhosphoSitePlus	COSMIC	11.681	Down-regulation
CAMK_MAPKAPK_MK2_MAPKAPK2_ST	Q9Y580	RBM7	P49137	MAPKAPK2	S136	Q132H	132	Missense	distal	-4	no	19.857	19.907	EPSD;PhosphoSitePlus	COSMIC	11.681	Up-regulation
CAMK_MAPKAPK_MK2_MAPKAPK2_ST	Q9Y580	RBM7	P49137	MAPKAPK2	S136	I130V	130	Missense	distal	-6	no	19.857	19.862	EPSD;PhosphoSitePlus	COSMIC	11.681	Up-regulation
CAMK_MAPKAPK_MK2_MAPKAPK2_ST	Q9Y580	RBM7	P49137	MAPKAPK2	S136	Q129H	129	Missense	distal	-7	no	19.857	19.861	EPSD;PhosphoSitePlus	COSMIC	11.681	Up-regulation
CAMK_MAPKAPK_MK2_MAPKAPK2_ST	Q9Y580	RBM7	P49137	MAPKAPK2	S155	G158R	158	Missense	distal	3	no	15.293	15.324	EPSD	COSMIC;GDSC;CCLE	11.681	Up-regulation
CAMK_MAPKAPK_MK2_MAPKAPK2_ST	Q9Y580	RBM7	P49137	MAPKAPK2	S155	G161A	161	Missense	distal	6	no	15.293	15.314	EPSD	COSMIC	11.681	Up-regulation
CAMK_MAPKAPK_MK2_MAPKAPK2_ST	Q9Y580	RBM7	P49137	MAPKAPK2	S178	S185F	185	Missense	distal	7	no	13.579	13.000	EPSD	COSMIC	11.681	Down-regulation
CAMK_MAPKAPK_MK2_MAPKAPK2_ST	Q9Y580	RBM7	P49137	MAPKAPK2	S178	S184F	184	Missense	distal	6	no	13.579	13.535	EPSD	COSMIC	11.681	Down-regulation
CAMK_MAPKAPK_MK2_MAPKAPK2_ST	Q9Y580	RBM7	P49137	MAPKAPK2	S180	S185F	185	Missense	distal	5	no	13.837	14.226	EPSD	COSMIC	11.681	Up-regulation
CAMK_MAPKAPK_MK2_MAPKAPK2_ST	Q9Y580	RBM7	P49137	MAPKAPK2	S180	S184F	184	Missense	distal	4	no	13.837	13.527	EPSD	COSMIC	11.681	Down-regulation
CAMK_MAPKAPK_MK2_MAPKAPK2_ST	Q9Y580	RBM7	P49137	MAPKAPK2	S186	S185F	185	Missense	proximal	-1	no	14.525	14.541	EPSD	COSMIC	11.681	Up-regulation
CAMK_MAPKAPK_MK2_MAPKAPK2_ST	Q9Y580	RBM7	P49137	MAPKAPK2	S186	S184F	184	Missense	proximal	-2	no	14.525	9.099	EPSD	COSMIC	11.681	Loss
CAMK_MAPKAPK_MK2_MAPKAPK2_ST	Q9Y580	RBM7	P49137	MAPKAPK2	S204	R198C	198	Missense	distal	-6	no	16.724	16.774	PhosphoSitePlus;EPSD	COSMIC	11.681	Up-regulation
CAMK_MAPKAPK_MK2_MAPKAPK2_ST	Q9Y580	RBM7	P49137	MAPKAPK2	S204	V200I	200	Missense	distal	-4	no	16.724	16.652	PhosphoSitePlus;EPSD	COSMIC	11.681	Down-regulation
CAMK_MAPKAPK_MK2_MAPKAPK2_ST	O00418	EEF2K	P49137	MAPKAPK2	S366	T364N	364	Missense	proximal	-2	no	16.411	15.801	EPSD	COSMIC	11.681	Down-regulation
CAMK_MAPKAPK_MK2_MAPKAPK2_ST	O00418	EEF2K	P49137	MAPKAPK2	S368	T364N	364	Missense	distal	-4	no	14.738	14.948	EPSD	COSMIC	11.681	Up-regulation
CAMK_MAPKAPK_MK2_MAPKAPK2_ST	O00418	EEF2K	P49137	MAPKAPK2	S368	P375S	375	Missense	distal	7	no	14.738	14.621	EPSD	COSMIC	11.681	Down-regulation
CAMK_MAPKAPK_MK2_MAPKAPK2_ST	O00418	EEF2K	P49137	MAPKAPK2	S377	E383D	383	Missense	distal	6	no	17.589	17.574	PhosphoSitePlus	COSMIC	11.681	Down-regulation
CAMK_MAPKAPK_MK2_MAPKAPK2_ST	O00418	EEF2K	P49137	MAPKAPK2	S377	S377L	377	Missense	central	0	yes	17.589	0.000	PhosphoSitePlus	COSMIC	11.681	Loss
CAMK_MAPKAPK_MK2_MAPKAPK2_ST	O00418	EEF2K	P49137	MAPKAPK2	S377	P375S	375	Missense	proximal	-2	no	17.589	20.820	PhosphoSitePlus	COSMIC	11.681	Up-regulation
CAMK_MAPKAPK_MK2_MAPKAPK2_ST	O00418	EEF2K	P49137	MAPKAPK2	S396	P394S	394	Missense	proximal	-2	no	8.514	11.745	EPSD	COSMIC	11.681	Gain
CAMK_MAPKAPK_MK2_MAPKAPK2_ST	O00418	EEF2K	P49137	MAPKAPK2	S398	S398C	398	Missense	central	0	yes	12.900	0.000	EPSD	COSMIC	11.681	Loss
CAMK_MAPKAPK_MK2_MAPKAPK2_ST	O00418	EEF2K	P49137	MAPKAPK2	S398	S399L	399	Missense	proximal	1	no	12.900	13.101	EPSD	COSMIC	11.681	Up-regulation
CAMK_MAPKAPK_MK2_MAPKAPK2_ST	O00418	EEF2K	P49137	MAPKAPK2	S398	P394L	394	Missense	distal	-4	no	12.900	13.024	EPSD	COSMIC;GDSC;CCLE	11.681	Up-regulation
CAMK_MAPKAPK_MK2_MAPKAPK2_ST	O00418	EEF2K	P49137	MAPKAPK2	S398	P394S	394	Missense	distal	-4	no	12.900	12.820	EPSD	COSMIC	11.681	Down-regulation
CAMK_MAPKAPK_MK2_MAPKAPK2_ST	O00418	EEF2K	P49137	MAPKAPK2	S462	E455D	455	Missense	distal	-7	no	12.213	12.253	EPSD	COSMIC	11.681	Up-regulation
CAMK_MAPKAPK_MK2_MAPKAPK2_ST	P07101	TH	P49137	MAPKAPK2	S19	R15S	15	Missense	distal	-4	no	19.504	19.492	EPSD;PhosphoSitePlus	COSMIC	11.681	Down-regulation
CAMK_MAPKAPK_MK2_MAPKAPK2_ST	P07101	TH	P49137	MAPKAPK2	S19	A17V	17	Missense	proximal	-2	no	19.504	17.303	EPSD;PhosphoSitePlus	COSMIC;CCLE	11.681	Down-regulation
CAMK_MAPKAPK_MK2_MAPKAPK2_ST	P07101	TH	P49137	MAPKAPK2	S19	S19C	19	Missense	central	0	yes	19.504	0.000	EPSD;PhosphoSitePlus	COSMIC;GDSC;CCLE	11.681	Loss
CAMK_MAPKAPK_MK2_MAPKAPK2_ST	P07101	TH	P49137	MAPKAPK2	S19	V18M	18	Missense	proximal	-1	no	19.504	19.509	EPSD;PhosphoSitePlus	COSMIC	11.681	Up-regulation
CAMK_MAPKAPK_MK2_MAPKAPK2_ST	P07101	TH	P49137	MAPKAPK2	S40	G38W	38	Missense	proximal	-2	no	12.767	12.087	EPSD;PhosphoSitePlus	COSMIC	11.681	Down-regulation
CAMK_MAPKAPK_MK2_MAPKAPK2_ST	P07101	TH	P49137	MAPKAPK2	S40	P45S	45	Missense	distal	5	no	12.767	12.684	EPSD;PhosphoSitePlus	COSMIC	11.681	Down-regulation
CAMK_MAPKAPK_MK2_MAPKAPK2_ST	P07101	TH	P49137	MAPKAPK2	S40	A36T	36	Missense	distal	-4	no	12.767	12.642	EPSD;PhosphoSitePlus	COSMIC	11.681	Down-regulation
CAMK_MAPKAPK_MK2_MAPKAPK2_ST	P07101	TH	P49137	MAPKAPK2	S40	P37L	37	Missense	distal	-3	no	12.767	12.341	EPSD;PhosphoSitePlus	COSMIC	11.681	Down-regulation
CAMK_MAPKAPK_MK2_MAPKAPK2_ST	P07101	TH	P49137	MAPKAPK2	S40	P45L	45	Missense	distal	5	no	12.767	12.853	EPSD;PhosphoSitePlus	COSMIC	11.681	Up-regulation
CAMK_MAPKAPK_MK2_MAPKAPK2_ST	P07101	TH	P49137	MAPKAPK2	S40	P47H	47	Missense	distal	7	no	12.767	12.213	EPSD;PhosphoSitePlus	COSMIC	11.681	Down-regulation
CAMK_MAPKAPK_MK2_MAPKAPK2_ST	P07101	TH	P49137	MAPKAPK2	S71	R64Q	64	Missense	distal	-7	no	19.024	19.111	EPSD;PhosphoSitePlus	COSMIC;CCLE	11.681	Up-regulation
CAMK_MAPKAPK_MK2_MAPKAPK2_ST	P07101	TH	P49137	MAPKAPK2	S118	V112M	112	Missense	distal	-6	no	12.033	12.030	EPSD	COSMIC	11.681	Down-regulation
CAMK_MAPKAPK_MK2_MAPKAPK2_ST	P07101	TH	P49137	MAPKAPK2	S118	R120S	120	Missense	proximal	2	no	12.033	12.137	EPSD	COSMIC	11.681	Up-regulation
CAMK_MAPKAPK_MK2_MAPKAPK2_ST	P07101	TH	P49137	MAPKAPK2	S435	L434M	434	Missense	proximal	-1	no	13.210	13.218	EPSD	COSMIC	11.681	Up-regulation
CAMK_MAPKAPK_MK2_MAPKAPK2_ST	P07101	TH	P49137	MAPKAPK2	S435	E439A	439	Missense	distal	4	no	13.210	13.292	EPSD	COSMIC	11.681	Up-regulation
CAMK_MAPKAPK_MK2_MAPKAPK2_ST	P07101	TH	P49137	MAPKAPK2	S435	G428W	428	Missense	distal	-7	no	13.210	13.196	EPSD	COSMIC	11.681	Down-regulation
CAMK_MAPKAPK_MK2_MAPKAPK2_ST	P07101	TH	P49137	MAPKAPK2	S435	L430M	430	Missense	distal	-5	no	13.210	12.455	EPSD	COSMIC	11.681	Down-regulation
CAMK_MAPKAPK_MK2_MAPKAPK2_ST	P05783	KRT18	P49137	MAPKAPK2	S7	T4I	4	Missense	distal	-3	no	11.220	11.806	EPSD	COSMIC	11.681	Gain
CAMK_MAPKAPK_MK2_MAPKAPK2_ST	P05783	KRT18	P49137	MAPKAPK2	S30	S23G	23	Missense	distal	-7	no	16.484	16.542	EPSD	COSMIC	11.681	Up-regulation
CAMK_MAPKAPK_MK2_MAPKAPK2_ST	P05783	KRT18	P49137	MAPKAPK2	S53	G59R	59	Missense	distal	6	no	19.256	19.284	PhosphoSitePlus	COSMIC	11.681	Up-regulation
CAMK_MAPKAPK_MK2_MAPKAPK2_ST	P05783	KRT18	P49137	MAPKAPK2	S53	G59E	59	Missense	distal	6	no	19.256	19.271	PhosphoSitePlus	COSMIC	11.681	Up-regulation
CAMK_MAPKAPK_MK2_MAPKAPK2_ST	P05783	KRT18	P49137	MAPKAPK2	S93	R90C	90	Missense	distal	-3	no	13.121	4.722	EPSD	COSMIC	11.681	Loss
CAMK_MAPKAPK_MK2_MAPKAPK2_ST	P05783	KRT18	P49137	MAPKAPK2	S93	S100R	100	Missense	distal	7	no	13.121	13.149	EPSD	COSMIC	11.681	Up-regulation
CAMK_MAPKAPK_MK2_MAPKAPK2_ST	P05783	KRT18	P49137	MAPKAPK2	S100	S100R	100	Missense	central	0	yes	16.165	0.000	EPSD	COSMIC	11.681	Loss
CAMK_MAPKAPK_MK2_MAPKAPK2_ST	P05783	KRT18	P49137	MAPKAPK2	S127	E134Q	134	Missense	distal	7	no	12.738	12.326	EPSD	COSMIC	11.681	Down-regulation
CAMK_MAPKAPK_MK2_MAPKAPK2_ST	P18615	NELFE	P49137	MAPKAPK2	S37	L32P	32	Missense	distal	-5	no	11.861	11.356	EPSD	COSMIC	11.681	Loss
CAMK_MAPKAPK_MK2_MAPKAPK2_ST	P18615	NELFE	P49137	MAPKAPK2	S37	G44C	44	Missense	distal	7	no	11.861	11.841	EPSD	COSMIC	11.681	Down-regulation
CAMK_MAPKAPK_MK2_MAPKAPK2_ST	P18615	NELFE	P49137	MAPKAPK2	S39	L32P	32	Missense	distal	-7	no	12.722	12.688	EPSD	COSMIC	11.681	Down-regulation
CAMK_MAPKAPK_MK2_MAPKAPK2_ST	P18615	NELFE	P49137	MAPKAPK2	S39	V46D	46	Missense	distal	7	no	12.722	12.834	EPSD	COSMIC	11.681	Up-regulation
CAMK_MAPKAPK_MK2_MAPKAPK2_ST	P18615	NELFE	P49137	MAPKAPK2	S39	G44C	44	Missense	distal	5	no	12.722	12.677	EPSD	COSMIC	11.681	Down-regulation
CAMK_MAPKAPK_MK2_MAPKAPK2_ST	P18615	NELFE	P49137	MAPKAPK2	S51	G45D	45	Missense	distal	-6	no	21.458	21.439	PhosphoSitePlus;EPSD	COSMIC	11.681	Down-regulation
CAMK_MAPKAPK_MK2_MAPKAPK2_ST	P18615	NELFE	P49137	MAPKAPK2	S51	V46D	46	Missense	distal	-5	no	21.458	20.495	PhosphoSitePlus;EPSD	COSMIC	11.681	Down-regulation
CAMK_MAPKAPK_MK2_MAPKAPK2_ST	P18615	NELFE	P49137	MAPKAPK2	S51	G44C	44	Missense	distal	-7	no	21.458	21.445	PhosphoSitePlus;EPSD	COSMIC	11.681	Down-regulation
CAMK_MAPKAPK_MK2_MAPKAPK2_ST	P18615	NELFE	P49137	MAPKAPK2	S115	Q111H	111	Missense	distal	-4	no	17.486	17.536	EPSD;PhosphoSitePlus	COSMIC	11.681	Up-regulation
CAMK_MAPKAPK_MK2_MAPKAPK2_ST	P18615	NELFE	P49137	MAPKAPK2	S123	R125T	125	Missense	proximal	2	no	13.347	13.475	EPSD	COSMIC	11.681	Up-regulation
CAMK_MAPKAPK_MK2_MAPKAPK2_ST	P18615	NELFE	P49137	MAPKAPK2	S181	R186W	186	Missense	distal	5	no	13.293	13.512	EPSD	COSMIC	11.681	Up-regulation
CAMK_MAPKAPK_MK2_MAPKAPK2_ST	P18615	NELFE	P49137	MAPKAPK2	S181	R184K	184	Missense	distal	3	no	13.293	13.218	EPSD	COSMIC	11.681	Down-regulation
CAMK_MAPKAPK_MK2_MAPKAPK2_ST	P18615	NELFE	P49137	MAPKAPK2	S181	R186H	186	Missense	distal	5	no	13.293	13.599	EPSD	COSMIC	11.681	Up-regulation
CAMK_MAPKAPK_MK2_MAPKAPK2_ST	P18615	NELFE	P49137	MAPKAPK2	S181	S187G	187	Missense	distal	6	no	13.293	13.262	EPSD	COSMIC	11.681	Down-regulation
CAMK_MAPKAPK_MK2_MAPKAPK2_ST	P18615	NELFE	P49137	MAPKAPK2	S187	R186W	186	Missense	proximal	-1	no	19.365	19.383	EPSD	COSMIC	11.681	Up-regulation
CAMK_MAPKAPK_MK2_MAPKAPK2_ST	P18615	NELFE	P49137	MAPKAPK2	S187	R184K	184	Missense	distal	-3	no	19.365	14.241	EPSD	COSMIC	11.681	Down-regulation
CAMK_MAPKAPK_MK2_MAPKAPK2_ST	P18615	NELFE	P49137	MAPKAPK2	S187	R186H	186	Missense	proximal	-1	no	19.365	19.387	EPSD	COSMIC	11.681	Up-regulation
CAMK_MAPKAPK_MK2_MAPKAPK2_ST	P18615	NELFE	P49137	MAPKAPK2	S187	S187G	187	Missense	central	0	yes	19.365	0.000	EPSD	COSMIC	11.681	Loss
CAMK_MAPKAPK_MK2_MAPKAPK2_ST	P18615	NELFE	P49137	MAPKAPK2	S191	R198Q	198	Missense	distal	7	no	15.717	15.354	EPSD	COSMIC	11.681	Down-regulation
CAMK_MAPKAPK_MK2_MAPKAPK2_ST	P18615	NELFE	P49137	MAPKAPK2	S191	R198W	198	Missense	distal	7	no	15.717	15.444	EPSD	COSMIC	11.681	Down-regulation
CAMK_MAPKAPK_MK2_MAPKAPK2_ST	P18615	NELFE	P49137	MAPKAPK2	S191	R186W	186	Missense	distal	-5	no	15.717	15.362	EPSD	COSMIC	11.681	Down-regulation
CAMK_MAPKAPK_MK2_MAPKAPK2_ST	P18615	NELFE	P49137	MAPKAPK2	S191	R184K	184	Missense	distal	-7	no	15.717	15.791	EPSD	COSMIC	11.681	Up-regulation
CAMK_MAPKAPK_MK2_MAPKAPK2_ST	P18615	NELFE	P49137	MAPKAPK2	S191	R196Q	196	Missense	distal	5	no	15.717	15.936	EPSD	COSMIC	11.681	Up-regulation
CAMK_MAPKAPK_MK2_MAPKAPK2_ST	P18615	NELFE	P49137	MAPKAPK2	S191	R186H	186	Missense	distal	-5	no	15.717	15.239	EPSD	COSMIC	11.681	Down-regulation
CAMK_MAPKAPK_MK2_MAPKAPK2_ST	P18615	NELFE	P49137	MAPKAPK2	S191	S187G	187	Missense	distal	-4	no	15.717	16.054	EPSD	COSMIC	11.681	Up-regulation
CAMK_MAPKAPK_MK2_MAPKAPK2_ST	P18615	NELFE	P49137	MAPKAPK2	S251	S251P	251	Missense	central	0	yes	19.741	0.000	EPSD;PhosphoSitePlus	COSMIC	11.681	Loss
CAMK_MAPKAPK_MK2_MAPKAPK2_ST	P18615	NELFE	P49137	MAPKAPK2	S251	R247H	247	Missense	distal	-4	no	19.741	19.981	EPSD;PhosphoSitePlus	COSMIC	11.681	Up-regulation
CAMK_MAPKAPK_MK2_MAPKAPK2_ST	P18615	NELFE	P49137	MAPKAPK2	S251	R255Q	255	Missense	distal	4	no	19.741	19.605	EPSD;PhosphoSitePlus	COSMIC	11.681	Down-regulation
CAMK_MAPKAPK_MK2_MAPKAPK2_ST	P18615	NELFE	P49137	MAPKAPK2	S251	A257T	257	Missense	distal	6	no	19.741	19.749	EPSD;PhosphoSitePlus	COSMIC	11.681	Up-regulation
CAMK_MAPKAPK_MK2_MAPKAPK2_ST	P18615	NELFE	P49137	MAPKAPK2	S281	G278E	278	Missense	distal	-3	no	6.487	11.851	EPSD	COSMIC	11.681	Gain
CAMK_MAPKAPK_MK2_MAPKAPK2_ST	P49137	MAPKAPK2	P49137	MAPKAPK2	S328	W324C	324	Missense	distal	-4	no	12.202	12.211	EPSD	COSMIC	11.681	Up-regulation
CAMK_MAPKAPK_MK2_MAPKAPK2_ST	P49137	MAPKAPK2	P49137	MAPKAPK2	S328	P335S	335	Missense	distal	7	no	12.202	12.085	EPSD	COSMIC	11.681	Down-regulation
CAMK_MAPKAPK_MK2_MAPKAPK2_ST	P49137	MAPKAPK2	P49137	MAPKAPK2	S328	T329I	329	Missense	proximal	1	no	12.202	12.154	EPSD	COSMIC	11.681	Down-regulation
CAMK_MAPKAPK_MK2_MAPKAPK2_ST	Q07352	ZFP36L1	P49137	MAPKAPK2	S54	L57Q	57	Missense	distal	3	no	16.902	16.853	EPSD;PhosphoSitePlus	COSMIC	11.681	Down-regulation
CAMK_MAPKAPK_MK2_MAPKAPK2_ST	Q07352	ZFP36L1	P49137	MAPKAPK2	S54	P50L	50	Missense	distal	-4	no	16.902	17.026	EPSD;PhosphoSitePlus	COSMIC	11.681	Up-regulation
CAMK_MAPKAPK_MK2_MAPKAPK2_ST	Q07352	ZFP36L1	P49137	MAPKAPK2	S80	A76D	76	Missense	distal	-4	no	11.677	11.800	EPSD	COSMIC	11.681	Gain
CAMK_MAPKAPK_MK2_MAPKAPK2_ST	Q07352	ZFP36L1	P49137	MAPKAPK2	S90	S92L	92	Missense	proximal	2	no	15.713	15.298	EPSD	COSMIC	11.681	Down-regulation
CAMK_MAPKAPK_MK2_MAPKAPK2_ST	Q07352	ZFP36L1	P49137	MAPKAPK2	S92	L98P	98	Missense	distal	6	no	20.305	20.309	PhosphoSitePlus;EPSD	COSMIC	11.681	Up-regulation
CAMK_MAPKAPK_MK2_MAPKAPK2_ST	Q07352	ZFP36L1	P49137	MAPKAPK2	S92	S92L	92	Missense	central	0	yes	20.305	0.000	PhosphoSitePlus;EPSD	COSMIC	11.681	Loss
CAMK_MAPKAPK_MK2_MAPKAPK2_ST	Q07352	ZFP36L1	P49137	MAPKAPK2	T148	T155M	155	Missense	distal	7	no	14.848	14.401	EPSD	COSMIC	11.681	Down-regulation
CAMK_MAPKAPK_MK2_MAPKAPK2_ST	Q07352	ZFP36L1	P49137	MAPKAPK2	S192	R195C	195	Missense	distal	3	no	12.901	12.851	EPSD	COSMIC	11.681	Down-regulation
CAMK_MAPKAPK_MK2_MAPKAPK2_ST	Q07352	ZFP36L1	P49137	MAPKAPK2	S192	A188T	188	Missense	distal	-4	no	12.901	12.776	EPSD	COSMIC	11.681	Down-regulation
CAMK_MAPKAPK_MK2_MAPKAPK2_ST	Q07352	ZFP36L1	P49137	MAPKAPK2	S192	L191F	191	Missense	proximal	-1	no	12.901	12.917	EPSD	COSMIC	11.681	Up-regulation
CAMK_MAPKAPK_MK2_MAPKAPK2_ST	Q07352	ZFP36L1	P49137	MAPKAPK2	S201	R195C	195	Missense	distal	-6	no	12.685	12.735	EPSD	COSMIC	11.681	Up-regulation
CAMK_MAPKAPK_MK2_MAPKAPK2_ST	Q07352	ZFP36L1	P49137	MAPKAPK2	S201	A205V	205	Missense	distal	4	no	12.685	12.534	EPSD	COSMIC	11.681	Down-regulation
CAMK_MAPKAPK_MK2_MAPKAPK2_ST	Q07352	ZFP36L1	P49137	MAPKAPK2	S201	H200R	200	Missense	proximal	-1	no	12.685	12.662	EPSD	COSMIC	11.681	Down-regulation
CAMK_MAPKAPK_MK2_MAPKAPK2_ST	Q07352	ZFP36L1	P49137	MAPKAPK2	S203	A205V	205	Missense	proximal	2	no	15.900	15.595	EPSD;PhosphoSitePlus	COSMIC	11.681	Down-regulation
CAMK_MAPKAPK_MK2_MAPKAPK2_ST	Q07352	ZFP36L1	P49137	MAPKAPK2	S203	H200R	200	Missense	distal	-3	no	15.900	20.660	EPSD;PhosphoSitePlus	COSMIC	11.681	Up-regulation
CAMK_MAPKAPK_MK2_MAPKAPK2_ST	Q07352	ZFP36L1	P49137	MAPKAPK2	S283	D290E	290	Missense	distal	7	no	17.575	17.764	EPSD	COSMIC	11.681	Up-regulation
CAMK_MAPKAPK_MK2_MAPKAPK2_ST	Q07352	ZFP36L1	P49137	MAPKAPK2	S314	S311C	311	Missense	distal	-3	no	11.767	9.697	EPSD	COSMIC;GDSC	11.681	Loss
CAMK_MAPKAPK_MK2_MAPKAPK2_ST	Q07352	ZFP36L1	P49137	MAPKAPK2	S316	S311C	311	Missense	distal	-5	no	14.018	13.567	EPSD	COSMIC;GDSC	11.681	Down-regulation
CAMK_MAPKAPK_MK2_MAPKAPK2_ST	Q9NQC3	RTN4	P49137	MAPKAPK2	S15	Q20R	20	Missense	distal	5	no	12.823	12.604	EPSD	COSMIC	11.681	Down-regulation
CAMK_MAPKAPK_MK2_MAPKAPK2_ST	Q9NQC3	RTN4	P49137	MAPKAPK2	S15	S11L	11	Missense	distal	-4	no	12.823	13.027	EPSD	COSMIC	11.681	Up-regulation
CAMK_MAPKAPK_MK2_MAPKAPK2_ST	Q9NQC3	RTN4	P49137	MAPKAPK2	S15	S12L	12	Missense	distal	-3	no	12.823	14.062	EPSD	COSMIC	11.681	Up-regulation
CAMK_MAPKAPK_MK2_MAPKAPK2_ST	Q9NQC3	RTN4	P49137	MAPKAPK2	S150	P145H	145	Missense	distal	-5	no	11.742	11.429	EPSD	COSMIC	11.681	Loss
CAMK_MAPKAPK_MK2_MAPKAPK2_ST	Q9NQC3	RTN4	P49137	MAPKAPK2	S181	D186N	186	Missense	distal	5	no	18.474	18.440	EPSD	COSMIC	11.681	Down-regulation
CAMK_MAPKAPK_MK2_MAPKAPK2_ST	Q9NQC3	RTN4	P49137	MAPKAPK2	S184	D186N	186	Missense	proximal	2	no	15.518	15.554	EPSD	COSMIC	11.681	Up-regulation
CAMK_MAPKAPK_MK2_MAPKAPK2_ST	Q9NQC3	RTN4	P49137	MAPKAPK2	S196	R201H	201	Missense	distal	5	no	14.712	15.018	EPSD	COSMIC;GDSC;CCLE	11.681	Up-regulation
CAMK_MAPKAPK_MK2_MAPKAPK2_ST	Q9NQC3	RTN4	P49137	MAPKAPK2	S196	R201C	201	Missense	distal	5	no	14.712	14.938	EPSD	COSMIC	11.681	Up-regulation
CAMK_MAPKAPK_MK2_MAPKAPK2_ST	Q9NQC3	RTN4	P49137	MAPKAPK2	S196	A194D	194	Missense	proximal	-2	no	14.712	11.948	EPSD	COSMIC	11.681	Down-regulation
CAMK_MAPKAPK_MK2_MAPKAPK2_ST	Q9NQC3	RTN4	P49137	MAPKAPK2	S218	N215H	215	Missense	distal	-3	no	10.956	12.743	EPSD	COSMIC	11.681	Gain
CAMK_MAPKAPK_MK2_MAPKAPK2_ST	Q9NQC3	RTN4	P49137	MAPKAPK2	S239	L241F	241	Missense	proximal	2	no	13.945	13.646	EPSD	COSMIC;GDSC;CCLE	11.681	Down-regulation
CAMK_MAPKAPK_MK2_MAPKAPK2_ST	Q9NQC3	RTN4	P49137	MAPKAPK2	S245	L241F	241	Missense	distal	-4	no	11.788	11.978	EPSD	COSMIC;GDSC;CCLE	11.681	Up-regulation
CAMK_MAPKAPK_MK2_MAPKAPK2_ST	Q9NQC3	RTN4	P49137	MAPKAPK2	S245	L252V	252	Missense	distal	7	no	11.788	11.920	EPSD	COSMIC	11.681	Up-regulation
CAMK_MAPKAPK_MK2_MAPKAPK2_ST	Q9NQC3	RTN4	P49137	MAPKAPK2	S305	S303L	303	Missense	proximal	-2	no	13.544	10.187	EPSD	COSMIC	11.681	Loss
CAMK_MAPKAPK_MK2_MAPKAPK2_ST	Q9NQC3	RTN4	P49137	MAPKAPK2	S305	S303G	303	Missense	proximal	-2	no	13.544	10.207	EPSD	COSMIC	11.681	Loss
CAMK_MAPKAPK_MK2_MAPKAPK2_ST	Q9NQC3	RTN4	P49137	MAPKAPK2	S749	L747S	747	Missense	proximal	-2	no	8.739	12.096	EPSD	COSMIC	11.681	Gain
CAMK_MAPKAPK_MK2_MAPKAPK2_ST	Q9NQC3	RTN4	P49137	MAPKAPK2	S881	R887M	887	Missense	distal	6	no	13.058	13.044	EPSD	COSMIC	11.681	Down-regulation
CAMK_MAPKAPK_MK2_MAPKAPK2_ST	Q9NQC3	RTN4	P49137	MAPKAPK2	T890	R887M	887	Missense	distal	-3	no	12.221	3.831	EPSD	COSMIC	11.681	Loss
CAMK_MAPKAPK_MK2_MAPKAPK2_ST	Q9NQC3	RTN4	P49137	MAPKAPK2	S993	S993P	993	Missense	central	0	yes	18.917	0.000	EPSD	COSMIC	11.681	Loss
CAMK_MAPKAPK_MK2_MAPKAPK2_ST	Q9NQC3	RTN4	P49137	MAPKAPK2	S1094	V1099G	1099	Missense	distal	5	no	12.406	12.513	EPSD	COSMIC	11.681	Up-regulation
CAMK_MAPKAPK_MK2_MAPKAPK2_ST	P53350	PLK1	P49137	MAPKAPK2	S326	A328T	328	Missense	proximal	2	no	12.908	12.960	PhosphoSitePlus;EPSD	COSMIC	11.681	Up-regulation
CAMK_MAPKAPK_MK2_MAPKAPK2_ST	P53350	PLK1	P49137	MAPKAPK2	S330	R337Q	337	Missense	distal	7	no	12.702	12.339	EPSD	COSMIC	11.681	Down-regulation
CAMK_MAPKAPK_MK2_MAPKAPK2_ST	P53350	PLK1	P49137	MAPKAPK2	S330	A328T	328	Missense	proximal	-2	no	12.702	12.542	EPSD	COSMIC	11.681	Down-regulation
CAMK_MAPKAPK_MK2_MAPKAPK2_ST	P53350	PLK1	P49137	MAPKAPK2	S330	S335R	335	Missense	distal	5	no	12.702	12.720	EPSD	COSMIC;GDSC;CCLE	11.681	Up-regulation
CAMK_MAPKAPK_MK2_MAPKAPK2_ST	P53350	PLK1	P49137	MAPKAPK2	S565	E569G	569	Missense	distal	4	no	12.059	11.928	EPSD	COSMIC	11.681	Down-regulation
CAMK_MAPKAPK_MK2_MAPKAPK2_ST	P53350	PLK1	P49137	MAPKAPK2	S592	S595L	595	Missense	distal	3	no	12.258	12.142	EPSD	COSMIC;GDSC;CCLE	11.681	Down-regulation
CAMK_MAPKAPK_MK2_MAPKAPK2_ST	P53350	PLK1	P49137	MAPKAPK2	S592	N598Y	598	Missense	distal	6	no	12.258	12.241	EPSD	COSMIC	11.681	Down-regulation
CAMK_MAPKAPK_MK2_MAPKAPK2_ST	P53350	PLK1	P49137	MAPKAPK2	S597	S595L	595	Missense	proximal	-2	no	18.136	14.779	EPSD	COSMIC;GDSC;CCLE	11.681	Down-regulation
CAMK_MAPKAPK_MK2_MAPKAPK2_ST	P53350	PLK1	P49137	MAPKAPK2	S597	N598Y	598	Missense	proximal	1	no	18.136	18.065	EPSD	COSMIC	11.681	Down-regulation
CAMK_MAPKAPK_MK2_MAPKAPK2_ST	P53350	PLK1	P49137	MAPKAPK2	S597	K601N	601	Missense	distal	4	no	18.136	18.182	EPSD	COSMIC;GDSC;CCLE	11.681	Up-regulation
CAMK_MAPKAPK_MK2_MAPKAPK2_ST	Q9UPN4	CEP131	P49137	MAPKAPK2	T23	P27L	27	Missense	distal	4	no	11.711	11.617	EPSD	COSMIC	11.681	Loss
CAMK_MAPKAPK_MK2_MAPKAPK2_ST	Q9UPN4	CEP131	P49137	MAPKAPK2	T23	S30Y	30	Missense	distal	7	no	11.711	11.216	EPSD	COSMIC	11.681	Loss
CAMK_MAPKAPK_MK2_MAPKAPK2_ST	Q9UPN4	CEP131	P49137	MAPKAPK2	S30	R31W	31	Missense	proximal	1	no	13.101	12.973	EPSD	COSMIC	11.681	Down-regulation
CAMK_MAPKAPK_MK2_MAPKAPK2_ST	Q9UPN4	CEP131	P49137	MAPKAPK2	S30	P27L	27	Missense	distal	-3	no	13.101	12.675	EPSD	COSMIC	11.681	Down-regulation
CAMK_MAPKAPK_MK2_MAPKAPK2_ST	Q9UPN4	CEP131	P49137	MAPKAPK2	S30	R32H	32	Missense	proximal	2	no	13.101	12.590	EPSD	COSMIC	11.681	Down-regulation
CAMK_MAPKAPK_MK2_MAPKAPK2_ST	Q9UPN4	CEP131	P49137	MAPKAPK2	S30	S30Y	30	Missense	central	0	yes	13.101	0.000	EPSD	COSMIC	11.681	Loss
CAMK_MAPKAPK_MK2_MAPKAPK2_ST	Q9UPN4	CEP131	P49137	MAPKAPK2	S30	A37T	37	Missense	distal	7	no	13.101	13.203	EPSD	COSMIC	11.681	Up-regulation
CAMK_MAPKAPK_MK2_MAPKAPK2_ST	Q9UPN4	CEP131	P49137	MAPKAPK2	S35	R31W	31	Missense	distal	-4	no	16.560	16.779	EPSD	COSMIC	11.681	Up-regulation
CAMK_MAPKAPK_MK2_MAPKAPK2_ST	Q9UPN4	CEP131	P49137	MAPKAPK2	S35	R32H	32	Missense	distal	-3	no	16.560	11.801	EPSD	COSMIC	11.681	Down-regulation
CAMK_MAPKAPK_MK2_MAPKAPK2_ST	Q9UPN4	CEP131	P49137	MAPKAPK2	S35	S30Y	30	Missense	distal	-5	no	16.560	15.741	EPSD	COSMIC	11.681	Down-regulation
CAMK_MAPKAPK_MK2_MAPKAPK2_ST	Q9UPN4	CEP131	P49137	MAPKAPK2	S35	A37T	37	Missense	proximal	2	no	16.560	16.613	EPSD	COSMIC	11.681	Up-regulation
CAMK_MAPKAPK_MK2_MAPKAPK2_ST	Q9UPN4	CEP131	P49137	MAPKAPK2	S47	S52N	52	Missense	distal	5	no	21.293	21.532	PhosphoSitePlus;EPSD	COSMIC	11.681	Up-regulation
CAMK_MAPKAPK_MK2_MAPKAPK2_ST	Q9UPN4	CEP131	P49137	MAPKAPK2	S47	E53V	53	Missense	distal	6	no	21.293	21.285	PhosphoSitePlus;EPSD	COSMIC	11.681	Down-regulation
CAMK_MAPKAPK_MK2_MAPKAPK2_ST	Q9UPN4	CEP131	P49137	MAPKAPK2	S47	V43I	43	Missense	distal	-4	no	21.293	21.221	PhosphoSitePlus;EPSD	COSMIC	11.681	Down-regulation
CAMK_MAPKAPK_MK2_MAPKAPK2_ST	Q9UPN4	CEP131	P49137	MAPKAPK2	S76	N77S	77	Missense	proximal	1	no	11.451	11.933	EPSD	COSMIC	11.681	Gain
CAMK_MAPKAPK_MK2_MAPKAPK2_ST	Q9UPN4	CEP131	P49137	MAPKAPK2	S76	N71S	71	Missense	distal	-5	no	11.451	12.148	EPSD	COSMIC	11.681	Gain
CAMK_MAPKAPK_MK2_MAPKAPK2_ST	Q9UPN4	CEP131	P49137	MAPKAPK2	S78	N77S	77	Missense	proximal	-1	no	20.416	20.401	EPSD;PhosphoSitePlus	COSMIC	11.681	Down-regulation
CAMK_MAPKAPK_MK2_MAPKAPK2_ST	Q9UPN4	CEP131	P49137	MAPKAPK2	S78	N71S	71	Missense	distal	-7	no	20.416	20.366	EPSD;PhosphoSitePlus	COSMIC	11.681	Down-regulation
CAMK_MAPKAPK_MK2_MAPKAPK2_ST	Q9UPN4	CEP131	P49137	MAPKAPK2	S78	T80M	80	Missense	proximal	2	no	20.416	20.124	EPSD;PhosphoSitePlus	COSMIC	11.681	Down-regulation
CAMK_MAPKAPK_MK2_MAPKAPK2_ST	Q9UPN4	CEP131	P49137	MAPKAPK2	S78	R74I	74	Missense	distal	-4	no	20.416	20.549	EPSD;PhosphoSitePlus	COSMIC	11.681	Up-regulation
CAMK_MAPKAPK_MK2_MAPKAPK2_ST	Q9UPN4	CEP131	P49137	MAPKAPK2	S78	Q84H	84	Missense	distal	6	no	20.416	20.406	EPSD;PhosphoSitePlus	COSMIC	11.681	Down-regulation
CAMK_MAPKAPK_MK2_MAPKAPK2_ST	Q9UPN4	CEP131	P49137	MAPKAPK2	S89	Q84H	84	Missense	distal	-5	no	18.455	18.696	EPSD	COSMIC	11.681	Up-regulation
CAMK_MAPKAPK_MK2_MAPKAPK2_ST	Q9UPN4	CEP131	P49137	MAPKAPK2	S89	G88S	88	Missense	proximal	-1	no	18.455	18.438	EPSD	COSMIC	11.681	Down-regulation
CAMK_MAPKAPK_MK2_MAPKAPK2_ST	Q9UPN4	CEP131	P49137	MAPKAPK2	S114	S107R	107	Missense	distal	-7	no	15.748	15.714	EPSD	COSMIC	11.681	Down-regulation
CAMK_MAPKAPK_MK2_MAPKAPK2_ST	Q9UPN4	CEP131	P49137	MAPKAPK2	S114	A118T	118	Missense	distal	4	no	15.748	15.774	EPSD	COSMIC	11.681	Up-regulation
CAMK_MAPKAPK_MK2_MAPKAPK2_ST	Q9UPN4	CEP131	P49137	MAPKAPK2	S114	S107T	107	Missense	distal	-7	no	15.748	15.718	EPSD	COSMIC	11.681	Down-regulation
CAMK_MAPKAPK_MK2_MAPKAPK2_ST	Q9UPN4	CEP131	P49137	MAPKAPK2	S120	A118T	118	Missense	proximal	-2	no	12.275	12.116	EPSD	COSMIC	11.681	Down-regulation
CAMK_MAPKAPK_MK2_MAPKAPK2_ST	Q9UPN4	CEP131	P49137	MAPKAPK2	S120	W126R	126	Missense	distal	6	no	12.275	12.301	EPSD	COSMIC	11.681	Up-regulation
CAMK_MAPKAPK_MK2_MAPKAPK2_ST	Q9UPN4	CEP131	P49137	MAPKAPK2	S146	R143W	143	Missense	distal	-3	no	16.590	8.011	EPSD	COSMIC	11.681	Loss
CAMK_MAPKAPK_MK2_MAPKAPK2_ST	Q9UPN4	CEP131	P49137	MAPKAPK2	S146	R143Q	143	Missense	distal	-3	no	16.590	10.827	EPSD	COSMIC	11.681	Loss
CAMK_MAPKAPK_MK2_MAPKAPK2_ST	Q9UPN4	CEP131	P49137	MAPKAPK2	S146	N141K	141	Missense	distal	-5	no	16.590	16.629	EPSD	COSMIC	11.681	Up-regulation
CAMK_MAPKAPK_MK2_MAPKAPK2_ST	Q9UPN4	CEP131	P49137	MAPKAPK2	S208	S202F	202	Missense	distal	-6	no	12.030	12.139	EPSD	COSMIC	11.681	Up-regulation
CAMK_MAPKAPK_MK2_MAPKAPK2_ST	Q9UPN4	CEP131	P49137	MAPKAPK2	S208	Q204L	204	Missense	distal	-4	no	12.030	12.033	EPSD	COSMIC	11.681	Up-regulation
CAMK_MAPKAPK_MK2_MAPKAPK2_ST	Q9UPN4	CEP131	P49137	MAPKAPK2	S208	N210S	210	Missense	proximal	2	no	12.030	12.446	EPSD	COSMIC	11.681	Up-regulation
CAMK_MAPKAPK_MK2_MAPKAPK2_ST	Q9UPN4	CEP131	P49137	MAPKAPK2	T244	R241L	241	Missense	distal	-3	no	12.707	7.617	EPSD	COSMIC	11.681	Loss
CAMK_MAPKAPK_MK2_MAPKAPK2_ST	Q9UPN4	CEP131	P49137	MAPKAPK2	T244	H238Q	238	Missense	distal	-6	no	12.707	12.697	EPSD	COSMIC	11.681	Down-regulation
CAMK_MAPKAPK_MK2_MAPKAPK2_ST	Q9UPN4	CEP131	P49137	MAPKAPK2	T244	A240T	240	Missense	distal	-4	no	12.707	12.582	EPSD	COSMIC	11.681	Down-regulation
CAMK_MAPKAPK_MK2_MAPKAPK2_ST	Q9UPN4	CEP131	P49137	MAPKAPK2	T244	G249D	249	Missense	distal	5	no	12.707	12.691	EPSD	COSMIC	11.681	Down-regulation
CAMK_MAPKAPK_MK2_MAPKAPK2_ST	Q9UPN4	CEP131	P49137	MAPKAPK2	T244	T244I	244	Missense	central	0	yes	12.707	0.000	EPSD	COSMIC	11.681	Loss
CAMK_MAPKAPK_MK2_MAPKAPK2_ST	Q9UPN4	CEP131	P49137	MAPKAPK2	T244	R241Q	241	Missense	distal	-3	no	12.707	6.943	EPSD	COSMIC	11.681	Loss
CAMK_MAPKAPK_MK2_MAPKAPK2_ST	Q9UPN4	CEP131	P49137	MAPKAPK2	T244	G245E	245	Missense	proximal	1	no	12.707	13.210	EPSD	COSMIC	11.681	Up-regulation
CAMK_MAPKAPK_MK2_MAPKAPK2_ST	Q9UPN4	CEP131	P49137	MAPKAPK2	S308	E310D	310	Missense	proximal	2	no	16.279	16.035	EPSD	COSMIC	11.681	Down-regulation
CAMK_MAPKAPK_MK2_MAPKAPK2_ST	Q9UPN4	CEP131	P49137	MAPKAPK2	S308	E310K	310	Missense	proximal	2	no	16.279	15.980	EPSD	COSMIC	11.681	Down-regulation
CAMK_MAPKAPK_MK2_MAPKAPK2_ST	Q9UPN4	CEP131	P49137	MAPKAPK2	S308	R305Q	305	Missense	distal	-3	no	16.279	10.515	EPSD	COSMIC	11.681	Loss
CAMK_MAPKAPK_MK2_MAPKAPK2_ST	Q9UPN4	CEP131	P49137	MAPKAPK2	S308	R305W	305	Missense	distal	-3	no	16.279	7.700	EPSD	COSMIC	11.681	Loss
CAMK_MAPKAPK_MK2_MAPKAPK2_ST	Q9UPN4	CEP131	P49137	MAPKAPK2	S416	P418L	418	Missense	proximal	2	no	15.297	15.074	EPSD	COSMIC	11.681	Down-regulation
CAMK_MAPKAPK_MK2_MAPKAPK2_ST	Q9UPN4	CEP131	P49137	MAPKAPK2	S416	D415N	415	Missense	proximal	-1	no	15.297	15.299	EPSD	COSMIC;GDSC	11.681	Up-regulation
CAMK_MAPKAPK_MK2_MAPKAPK2_ST	Q9UPN4	CEP131	P49137	MAPKAPK2	S416	C410Y	410	Missense	distal	-6	no	15.297	15.338	EPSD	COSMIC	11.681	Up-regulation
CAMK_MAPKAPK_MK2_MAPKAPK2_ST	Q9UPN4	CEP131	P49137	MAPKAPK2	S613	A611T	611	Missense	proximal	-2	no	12.060	11.900	EPSD	COSMIC	11.681	Down-regulation
CAMK_MAPKAPK_MK2_MAPKAPK2_ST	Q9UPN4	CEP131	P49137	MAPKAPK2	S613	R618Q	618	Missense	distal	5	no	12.060	12.279	EPSD	COSMIC	11.681	Up-regulation
CAMK_MAPKAPK_MK2_MAPKAPK2_ST	Q9UPN4	CEP131	P49137	MAPKAPK2	S613	R618W	618	Missense	distal	5	no	12.060	12.279	EPSD	COSMIC	11.681	Up-regulation
CAMK_MAPKAPK_MK2_MAPKAPK2_ST	Q9UPN4	CEP131	P49137	MAPKAPK2	S731	L729M	729	Missense	proximal	-2	no	15.457	16.688	EPSD	COSMIC	11.681	Up-regulation
CAMK_MAPKAPK_MK2_MAPKAPK2_ST	Q9UPN4	CEP131	P49137	MAPKAPK2	S731	R727W	727	Missense	distal	-4	no	15.457	15.675	EPSD	COSMIC	11.681	Up-regulation
CAMK_MAPKAPK_MK2_MAPKAPK2_ST	Q9UPN4	CEP131	P49137	MAPKAPK2	S731	L732M	732	Missense	proximal	1	no	15.457	15.086	EPSD	COSMIC	11.681	Down-regulation
CAMK_MAPKAPK_MK2_MAPKAPK2_ST	Q9UPN4	CEP131	P49137	MAPKAPK2	S731	R727L	727	Missense	distal	-4	no	15.457	15.649	EPSD	COSMIC	11.681	Up-regulation
CAMK_MAPKAPK_MK2_MAPKAPK2_ST	Q9UPN4	CEP131	P49137	MAPKAPK2	S745	R747C	747	Missense	proximal	2	no	12.149	11.853	EPSD	COSMIC;GDSC	11.681	Down-regulation
CAMK_MAPKAPK_MK2_MAPKAPK2_ST	Q9UPN4	CEP131	P49137	MAPKAPK2	S745	R750C	750	Missense	distal	5	no	12.149	12.374	EPSD	COSMIC	11.681	Up-regulation
CAMK_MAPKAPK_MK2_MAPKAPK2_ST	Q9UPN4	CEP131	P49137	MAPKAPK2	S745	S740L	740	Missense	distal	-5	no	12.149	12.643	EPSD	COSMIC	11.681	Up-regulation
CAMK_MAPKAPK_MK2_MAPKAPK2_ST	Q9UPN4	CEP131	P49137	MAPKAPK2	S745	R747H	747	Missense	proximal	2	no	12.149	11.638	EPSD	COSMIC	11.681	Loss
CAMK_MAPKAPK_MK2_MAPKAPK2_ST	Q9UPN4	CEP131	P49137	MAPKAPK2	S798	E799Q	799	Missense	proximal	1	no	14.895	14.382	EPSD	COSMIC	11.681	Down-regulation
CAMK_MAPKAPK_MK2_MAPKAPK2_ST	Q9UPN4	CEP131	P49137	MAPKAPK2	S798	R795Q	795	Missense	distal	-3	no	14.895	9.131	EPSD	COSMIC	11.681	Loss
CAMK_MAPKAPK_MK2_MAPKAPK2_ST	Q9UPN4	CEP131	P49137	MAPKAPK2	S798	R795W	795	Missense	distal	-3	no	14.895	6.316	EPSD	COSMIC	11.681	Loss
CAMK_MAPKAPK_MK2_MAPKAPK2_ST	Q9UPN4	CEP131	P49137	MAPKAPK2	S798	L796Q	796	Missense	proximal	-2	no	14.895	15.993	EPSD	COSMIC	11.681	Up-regulation
CAMK_MAPKAPK_MK2_MAPKAPK2_ST	Q9UPN4	CEP131	P49137	MAPKAPK2	S798	E802Q	802	Missense	distal	4	no	14.895	14.753	EPSD	COSMIC	11.681	Down-regulation
CAMK_MAPKAPK_MK2_MAPKAPK2_ST	Q9UPN4	CEP131	P49137	MAPKAPK2	S990	N995I	995	Missense	distal	5	no	13.388	13.352	EPSD	COSMIC	11.681	Down-regulation
CAMK_MAPKAPK_MK2_MAPKAPK2_ST	Q9UPN4	CEP131	P49137	MAPKAPK2	S990	A984E	984	Missense	distal	-6	no	13.388	13.379	EPSD	COSMIC	11.681	Down-regulation
CAMK_MAPKAPK_MK2_MAPKAPK2_ST	Q9UPN4	CEP131	P49137	MAPKAPK2	S990	R993C	993	Missense	distal	3	no	13.388	13.338	EPSD	COSMIC	11.681	Down-regulation
CAMK_MAPKAPK_MK2_MAPKAPK2_ST	Q9UPN4	CEP131	P49137	MAPKAPK2	S990	S990F	990	Missense	central	0	yes	13.388	0.000	EPSD	COSMIC	11.681	Loss
CAMK_MAPKAPK_MK2_MAPKAPK2_ST	Q9UPN4	CEP131	P49137	MAPKAPK2	S1052	A1050V	1050	Missense	proximal	-2	no	12.011	9.810	EPSD	COSMIC	11.681	Loss
CAMK_MAPKAPK_MK2_MAPKAPK2_ST	Q9UPN4	CEP131	P49137	MAPKAPK2	S1052	E1059K	1059	Missense	distal	7	no	12.011	11.738	EPSD	COSMIC	11.681	Down-regulation
CAMK_MAPKAPK_MK2_MAPKAPK2_ST	Q9UPN4	CEP131	P49137	MAPKAPK2	S1052	A1045V	1045	Missense	distal	-7	no	12.011	12.055	EPSD	COSMIC	11.681	Up-regulation
CAMK_MAPKAPK_MK2_MAPKAPK2_ST	Q9UPN4	CEP131	P49137	MAPKAPK2	S1052	E1059D	1059	Missense	distal	7	no	12.011	11.822	EPSD	COSMIC	11.681	Down-regulation
CAMK_MAPKAPK_MK2_MAPKAPK2_ST	Q9UPN4	CEP131	P49137	MAPKAPK2	S1052	R1055L	1055	Missense	distal	3	no	12.011	11.964	EPSD	COSMIC	11.681	Down-regulation
CAMK_MAPKAPK_MK2_MAPKAPK2_ST	Q9UPN4	CEP131	P49137	MAPKAPK2	T1079	T1079M	1079	Missense	central	0	yes	12.633	0.000	EPSD	COSMIC	11.681	Loss
CAMK_MAPKAPK_MK2_MAPKAPK2_ST	Q9UPN4	CEP131	P49137	MAPKAPK2	T1079	P1078T	1078	Missense	proximal	-1	no	12.633	12.628	EPSD	COSMIC	11.681	Down-regulation
CAMK_MAPKAPK_MK2_MAPKAPK2_ST	P31749	AKT1	P49137	MAPKAPK2	T65	L62R	62	Missense	distal	-3	no	7.780	12.871	EPSD	COSMIC	11.681	Gain
CAMK_MAPKAPK_MK2_MAPKAPK2_ST	P31749	AKT1	P49137	MAPKAPK2	S124	G123D	123	Missense	proximal	-1	no	19.183	19.178	EPSD	COSMIC	11.681	Down-regulation
CAMK_MAPKAPK_MK2_MAPKAPK2_ST	P31749	AKT1	P49137	MAPKAPK2	S124	D127N	127	Missense	distal	3	no	19.183	19.135	EPSD	COSMIC	11.681	Down-regulation
CAMK_MAPKAPK_MK2_MAPKAPK2_ST	P31749	AKT1	P49137	MAPKAPK2	S124	G130R	130	Missense	distal	6	no	19.183	19.211	EPSD	COSMIC	11.681	Up-regulation
CAMK_MAPKAPK_MK2_MAPKAPK2_ST	P31749	AKT1	P49137	MAPKAPK2	S246	A250V	250	Missense	distal	4	no	13.107	12.956	EPSD	COSMIC	11.681	Down-regulation
CAMK_MAPKAPK_MK2_MAPKAPK2_ST	P31749	AKT1	P49137	MAPKAPK2	S246	Y253C	253	Missense	distal	7	no	13.107	13.376	EPSD	COSMIC	11.681	Up-regulation
CAMK_MAPKAPK_MK2_MAPKAPK2_ST	P31749	AKT1	P49137	MAPKAPK2	S246	R243H	243	Missense	distal	-3	no	13.107	8.348	EPSD	COSMIC	11.681	Loss
CAMK_MAPKAPK_MK2_MAPKAPK2_ST	P31749	AKT1	P49137	MAPKAPK2	S246	S240C	240	Missense	distal	-6	no	13.107	13.169	EPSD	COSMIC	11.681	Up-regulation
CAMK_MAPKAPK_MK2_MAPKAPK2_ST	P31749	AKT1	P49137	MAPKAPK2	S473	S477N	477	Missense	distal	4	no	12.620	12.426	PhosphoSitePlus	COSMIC	11.681	Down-regulation
CAMK_MAPKAPK_MK2_MAPKAPK2_ST	P31749	AKT1	P49137	MAPKAPK2	S473	P470L	470	Missense	distal	-3	no	12.620	12.194	PhosphoSitePlus	COSMIC	11.681	Down-regulation
CAMK_MAPKAPK_MK2_MAPKAPK2_ST	P31749	AKT1	P49137	MAPKAPK2	S477	S477N	477	Missense	central	0	yes	12.069	0.000	EPSD	COSMIC	11.681	Loss
CAMK_MAPKAPK_MK2_MAPKAPK2_ST	P31749	AKT1	P49137	MAPKAPK2	S477	P470L	470	Missense	distal	-7	no	12.069	12.103	EPSD	COSMIC	11.681	Up-regulation
CAMK_MAPKAPK_MK2_MAPKAPK2_ST	O15511	ARPC5	P49137	MAPKAPK2	S77	A75E	75	Missense	proximal	-2	no	16.791	14.942	PhosphoSitePlus	COSMIC;GDSC	11.681	Down-regulation
CAMK_MAPKAPK_MK2_MAPKAPK2_ST	O15511	ARPC5	P49137	MAPKAPK2	S77	R74W	74	Missense	distal	-3	no	16.791	8.213	PhosphoSitePlus	COSMIC	11.681	Loss
CAMK_MAPKAPK_MK2_MAPKAPK2_ST	O15511	ARPC5	P49137	MAPKAPK2	T146	R143C	143	Missense	distal	-3	no	11.823	3.423	EPSD	COSMIC	11.681	Loss
CAMK_MAPKAPK_MK2_MAPKAPK2_ST	P04637	TP53	P49137	MAPKAPK2	S15	P13S	13	Missense	proximal	-2	no	10.279	13.510	EPSD	COSMIC	11.681	Gain
CAMK_MAPKAPK_MK2_MAPKAPK2_ST	P04637	TP53	P49137	MAPKAPK2	S20	S20L	20	Missense	central	0	yes	12.451	0.000	PhosphoSitePlus	COSMIC	11.681	Loss
CAMK_MAPKAPK_MK2_MAPKAPK2_ST	P04637	TP53	P49137	MAPKAPK2	S20	Q16L	16	Missense	distal	-4	no	12.451	12.454	PhosphoSitePlus	COSMIC;GDSC;CCLE	11.681	Up-regulation
CAMK_MAPKAPK_MK2_MAPKAPK2_ST	P04637	TP53	P49137	MAPKAPK2	S20	P13S	13	Missense	distal	-7	no	12.451	12.453	PhosphoSitePlus	COSMIC	11.681	Up-regulation
CAMK_MAPKAPK_MK2_MAPKAPK2_ST	P04637	TP53	P49137	MAPKAPK2	S20	E17K	17	Missense	distal	-3	no	12.451	12.623	PhosphoSitePlus	COSMIC	11.681	Up-regulation
CAMK_MAPKAPK_MK2_MAPKAPK2_ST	P04637	TP53	P49137	MAPKAPK2	S20	P13L	13	Missense	distal	-7	no	12.451	12.486	PhosphoSitePlus	COSMIC	11.681	Up-regulation
CAMK_MAPKAPK_MK2_MAPKAPK2_ST	P04637	TP53	P49137	MAPKAPK2	S20	L26P	26	Missense	distal	6	no	12.451	12.455	PhosphoSitePlus	COSMIC	11.681	Up-regulation
CAMK_MAPKAPK_MK2_MAPKAPK2_ST	P04637	TP53	P49137	MAPKAPK2	S20	T18A	18	Missense	proximal	-2	no	12.451	12.611	PhosphoSitePlus	COSMIC	11.681	Up-regulation
CAMK_MAPKAPK_MK2_MAPKAPK2_ST	P04637	TP53	P49137	MAPKAPK2	S20	F19S	19	Missense	proximal	-1	no	12.451	12.435	PhosphoSitePlus	COSMIC	11.681	Down-regulation
CAMK_MAPKAPK_MK2_MAPKAPK2_ST	P04637	TP53	P49137	MAPKAPK2	S20	E17V	17	Missense	distal	-3	no	12.451	10.018	PhosphoSitePlus	COSMIC	11.681	Loss
CAMK_MAPKAPK_MK2_MAPKAPK2_ST	P04637	TP53	P49137	MAPKAPK2	S20	P27T	27	Missense	distal	7	no	12.451	12.637	PhosphoSitePlus	COSMIC	11.681	Up-regulation
CAMK_MAPKAPK_MK2_MAPKAPK2_ST	P04637	TP53	P49137	MAPKAPK2	S20	T18I	18	Missense	proximal	-2	no	12.451	9.864	PhosphoSitePlus	COSMIC	11.681	Loss
CAMK_MAPKAPK_MK2_MAPKAPK2_ST	P04637	TP53	P49137	MAPKAPK2	S20	T18K	18	Missense	proximal	-2	no	12.451	9.765	PhosphoSitePlus	COSMIC	11.681	Loss
CAMK_MAPKAPK_MK2_MAPKAPK2_ST	P04637	TP53	P49137	MAPKAPK2	S20	T18R	18	Missense	proximal	-2	no	12.451	11.939	PhosphoSitePlus	COSMIC	11.681	Down-regulation
CAMK_MAPKAPK_MK2_MAPKAPK2_ST	P04637	TP53	P49137	MAPKAPK2	S20	S15I	15	Missense	distal	-5	no	12.451	12.757	PhosphoSitePlus	COSMIC	11.681	Up-regulation
CAMK_MAPKAPK_MK2_MAPKAPK2_ST	P04637	TP53	P49137	MAPKAPK2	S127	C124L	124	Missense	distal	-3	no	8.447	11.756	EPSD	COSMIC	11.681	Gain
CAMK_MAPKAPK_MK2_MAPKAPK2_ST	P04637	TP53	P49137	MAPKAPK2	S149	W146R	146	Missense	distal	-3	no	5.018	13.597	EPSD	COSMIC	11.681	Gain
CAMK_MAPKAPK_MK2_MAPKAPK2_ST	P04637	TP53	P49137	MAPKAPK2	S183	G187V	187	Missense	distal	4	no	12.691	12.753	EPSD	COSMIC	11.681	Up-regulation
CAMK_MAPKAPK_MK2_MAPKAPK2_ST	P04637	TP53	P49137	MAPKAPK2	S183	G187D	187	Missense	distal	4	no	12.691	12.686	EPSD	COSMIC	11.681	Down-regulation
CAMK_MAPKAPK_MK2_MAPKAPK2_ST	P04637	TP53	P49137	MAPKAPK2	S183	G187A	187	Missense	distal	4	no	12.691	12.903	EPSD	COSMIC	11.681	Up-regulation
CAMK_MAPKAPK_MK2_MAPKAPK2_ST	P04637	TP53	P49137	MAPKAPK2	S183	S183C	183	Missense	central	0	yes	12.691	0.000	EPSD	COSMIC	11.681	Loss
CAMK_MAPKAPK_MK2_MAPKAPK2_ST	P04637	TP53	P49137	MAPKAPK2	S183	S183P	183	Missense	central	0	yes	12.691	0.000	EPSD	COSMIC	11.681	Loss
CAMK_MAPKAPK_MK2_MAPKAPK2_ST	P04637	TP53	P49137	MAPKAPK2	S183	S185G	185	Missense	proximal	2	no	12.691	12.257	EPSD	COSMIC	11.681	Down-regulation
CAMK_MAPKAPK_MK2_MAPKAPK2_ST	P04637	TP53	P49137	MAPKAPK2	S183	P190N	190	Missense	distal	7	no	12.691	12.284	EPSD	COSMIC	11.681	Down-regulation
CAMK_MAPKAPK_MK2_MAPKAPK2_ST	P04637	TP53	P49137	MAPKAPK2	S183	D184N	184	Missense	proximal	1	no	12.691	12.560	EPSD	COSMIC	11.681	Down-regulation
CAMK_MAPKAPK_MK2_MAPKAPK2_ST	P04637	TP53	P49137	MAPKAPK2	S183	S185R	185	Missense	proximal	2	no	12.691	12.587	EPSD	COSMIC	11.681	Down-regulation
CAMK_MAPKAPK_MK2_MAPKAPK2_ST	P04637	TP53	P49137	MAPKAPK2	S183	S183L	183	Missense	central	0	yes	12.691	0.000	EPSD	COSMIC	11.681	Loss
CAMK_MAPKAPK_MK2_MAPKAPK2_ST	P04637	TP53	P49137	MAPKAPK2	S183	R181L	181	Missense	proximal	-2	no	12.691	11.601	EPSD	COSMIC	11.681	Loss
CAMK_MAPKAPK_MK2_MAPKAPK2_ST	P04637	TP53	P49137	MAPKAPK2	S183	H178P	178	Missense	distal	-5	no	12.691	13.005	EPSD	COSMIC	11.681	Up-regulation
CAMK_MAPKAPK_MK2_MAPKAPK2_ST	P04637	TP53	P49137	MAPKAPK2	S183	D186N	186	Missense	distal	3	no	12.691	12.644	EPSD	COSMIC	11.681	Down-regulation
CAMK_MAPKAPK_MK2_MAPKAPK2_ST	P04637	TP53	P49137	MAPKAPK2	S183	A189S	189	Missense	distal	6	no	12.691	12.702	EPSD	COSMIC	11.681	Up-regulation
CAMK_MAPKAPK_MK2_MAPKAPK2_ST	P04637	TP53	P49137	MAPKAPK2	S183	H178L	178	Missense	distal	-5	no	12.691	13.510	EPSD	COSMIC	11.681	Up-regulation
CAMK_MAPKAPK_MK2_MAPKAPK2_ST	P04637	TP53	P49137	MAPKAPK2	S183	D184Y	184	Missense	proximal	1	no	12.691	12.488	EPSD	COSMIC	11.681	Down-regulation
CAMK_MAPKAPK_MK2_MAPKAPK2_ST	P04637	TP53	P49137	MAPKAPK2	S183	L188V	188	Missense	distal	5	no	12.691	12.705	EPSD	COSMIC	11.681	Up-regulation
CAMK_MAPKAPK_MK2_MAPKAPK2_ST	P04637	TP53	P49137	MAPKAPK2	S183	A189V	189	Missense	distal	6	no	12.691	12.678	EPSD	COSMIC	11.681	Down-regulation
CAMK_MAPKAPK_MK2_MAPKAPK2_ST	P04637	TP53	P49137	MAPKAPK2	S183	H178Y	178	Missense	distal	-5	no	12.691	12.196	EPSD	COSMIC	11.681	Down-regulation
CAMK_MAPKAPK_MK2_MAPKAPK2_ST	P04637	TP53	P49137	MAPKAPK2	S183	D186E	186	Missense	distal	3	no	12.691	12.785	EPSD	COSMIC	11.681	Up-regulation
CAMK_MAPKAPK_MK2_MAPKAPK2_ST	P04637	TP53	P49137	MAPKAPK2	S183	C182Y	182	Missense	proximal	-1	no	12.691	12.699	EPSD	COSMIC	11.681	Up-regulation
CAMK_MAPKAPK_MK2_MAPKAPK2_ST	P04637	TP53	P49137	MAPKAPK2	S183	D186H	186	Missense	distal	3	no	12.691	12.595	EPSD	COSMIC	11.681	Down-regulation
CAMK_MAPKAPK_MK2_MAPKAPK2_ST	P04637	TP53	P49137	MAPKAPK2	S183	L188Q	188	Missense	distal	5	no	12.691	12.760	EPSD	COSMIC	11.681	Up-regulation
CAMK_MAPKAPK_MK2_MAPKAPK2_ST	P04637	TP53	P49137	MAPKAPK2	S183	H178N	178	Missense	distal	-5	no	12.691	12.318	EPSD	COSMIC	11.681	Down-regulation
CAMK_MAPKAPK_MK2_MAPKAPK2_ST	P04637	TP53	P49137	MAPKAPK2	S183	G187R	187	Missense	distal	4	no	12.691	12.816	EPSD	COSMIC;GDSC	11.681	Up-regulation
CAMK_MAPKAPK_MK2_MAPKAPK2_ST	P04637	TP53	P49137	MAPKAPK2	S183	C182S	182	Missense	proximal	-1	no	12.691	12.681	EPSD	COSMIC	11.681	Down-regulation
CAMK_MAPKAPK_MK2_MAPKAPK2_ST	P04637	TP53	P49137	MAPKAPK2	S183	P190F	190	Missense	distal	7	no	12.691	11.995	EPSD	COSMIC	11.681	Down-regulation
CAMK_MAPKAPK_MK2_MAPKAPK2_ST	P04637	TP53	P49137	MAPKAPK2	S183	G187C	187	Missense	distal	4	no	12.691	12.703	EPSD	COSMIC	11.681	Up-regulation
CAMK_MAPKAPK_MK2_MAPKAPK2_ST	P04637	TP53	P49137	MAPKAPK2	S183	S185T	185	Missense	proximal	2	no	12.691	12.715	EPSD	COSMIC	11.681	Up-regulation
CAMK_MAPKAPK_MK2_MAPKAPK2_ST	P04637	TP53	P49137	MAPKAPK2	S183	P190H	190	Missense	distal	7	no	12.691	12.138	EPSD	COSMIC	11.681	Down-regulation
CAMK_MAPKAPK_MK2_MAPKAPK2_ST	P04637	TP53	P49137	MAPKAPK2	S183	S185N	185	Missense	proximal	2	no	12.691	12.276	EPSD	COSMIC	11.681	Down-regulation
CAMK_MAPKAPK_MK2_MAPKAPK2_ST	P04637	TP53	P49137	MAPKAPK2	S183	D186G	186	Missense	distal	3	no	12.691	12.701	EPSD	COSMIC	11.681	Up-regulation
CAMK_MAPKAPK_MK2_MAPKAPK2_ST	P04637	TP53	P49137	MAPKAPK2	S183	D186V	186	Missense	distal	3	no	12.691	12.742	EPSD	COSMIC	11.681	Up-regulation
CAMK_MAPKAPK_MK2_MAPKAPK2_ST	P04637	TP53	P49137	MAPKAPK2	S183	P177I	177	Missense	distal	-6	no	12.691	12.730	EPSD	COSMIC	11.681	Up-regulation
CAMK_MAPKAPK_MK2_MAPKAPK2_ST	P04637	TP53	P49137	MAPKAPK2	S183	P190A	190	Missense	distal	7	no	12.691	12.775	EPSD	COSMIC	11.681	Up-regulation
CAMK_MAPKAPK_MK2_MAPKAPK2_ST	P04637	TP53	P49137	MAPKAPK2	S183	S185C	185	Missense	proximal	2	no	12.691	12.292	EPSD	COSMIC	11.681	Down-regulation
CAMK_MAPKAPK_MK2_MAPKAPK2_ST	P04637	TP53	P49137	MAPKAPK2	S183	S185I	185	Missense	proximal	2	no	12.691	12.274	EPSD	COSMIC	11.681	Down-regulation
CAMK_MAPKAPK_MK2_MAPKAPK2_ST	P04637	TP53	P49137	MAPKAPK2	S183	A189P	189	Missense	distal	6	no	12.691	12.685	EPSD	COSMIC	11.681	Down-regulation
CAMK_MAPKAPK_MK2_MAPKAPK2_ST	P04637	TP53	P49137	MAPKAPK2	S183	E180Q	180	Missense	distal	-3	no	12.691	12.223	EPSD	COSMIC	11.681	Down-regulation
CAMK_MAPKAPK_MK2_MAPKAPK2_ST	P04637	TP53	P49137	MAPKAPK2	S183	R181S	181	Missense	proximal	-2	no	12.691	14.958	EPSD	COSMIC	11.681	Up-regulation
CAMK_MAPKAPK_MK2_MAPKAPK2_ST	P04637	TP53	P49137	MAPKAPK2	S183	C182R	182	Missense	proximal	-1	no	12.691	12.671	EPSD	COSMIC	11.681	Down-regulation
CAMK_MAPKAPK_MK2_MAPKAPK2_ST	P04637	TP53	P49137	MAPKAPK2	S183	E180G	180	Missense	distal	-3	no	12.691	7.327	EPSD	COSMIC	11.681	Loss
CAMK_MAPKAPK_MK2_MAPKAPK2_ST	P04637	TP53	P49137	MAPKAPK2	S183	L188M	188	Missense	distal	5	no	12.691	12.660	EPSD	COSMIC	11.681	Down-regulation
CAMK_MAPKAPK_MK2_MAPKAPK2_ST	P04637	TP53	P49137	MAPKAPK2	S183	P177F	177	Missense	distal	-6	no	12.691	12.800	EPSD	COSMIC	11.681	Up-regulation
CAMK_MAPKAPK_MK2_MAPKAPK2_ST	P04637	TP53	P49137	MAPKAPK2	S183	D184E	184	Missense	proximal	1	no	12.691	13.125	EPSD	COSMIC	11.681	Up-regulation
CAMK_MAPKAPK_MK2_MAPKAPK2_ST	P04637	TP53	P49137	MAPKAPK2	S183	A189G	189	Missense	distal	6	no	12.691	12.670	EPSD	COSMIC	11.681	Down-regulation
CAMK_MAPKAPK_MK2_MAPKAPK2_ST	P04637	TP53	P49137	MAPKAPK2	S183	R181G	181	Missense	proximal	-2	no	12.691	11.621	EPSD	COSMIC	11.681	Loss
CAMK_MAPKAPK_MK2_MAPKAPK2_ST	P04637	TP53	P49137	MAPKAPK2	S183	D186X	186	Missense	distal	3	no	12.691	12.687	EPSD	COSMIC	11.681	Down-regulation
CAMK_MAPKAPK_MK2_MAPKAPK2_ST	P04637	TP53	P49137	MAPKAPK2	S183	R181Y	181	Missense	proximal	-2	no	12.691	10.087	EPSD	COSMIC	11.681	Loss
CAMK_MAPKAPK_MK2_MAPKAPK2_ST	P04637	TP53	P49137	MAPKAPK2	S183	D184G	184	Missense	proximal	1	no	12.691	12.622	EPSD	COSMIC	11.681	Down-regulation
CAMK_MAPKAPK_MK2_MAPKAPK2_ST	P04637	TP53	P49137	MAPKAPK2	S215	F212L	212	Missense	distal	-3	no	5.642	11.756	EPSD	COSMIC	11.681	Gain
CAMK_MAPKAPK_MK2_MAPKAPK2_ST	P04637	TP53	P49137	MAPKAPK2	S269	G266T	266	Missense	distal	-3	no	8.205	12.989	EPSD	COSMIC	11.681	Gain
CAMK_MAPKAPK_MK2_MAPKAPK2_ST	P04637	TP53	P49137	MAPKAPK2	S269	G266K	266	Missense	distal	-3	no	8.205	13.741	EPSD	COSMIC	11.681	Gain
CAMK_MAPKAPK_MK2_MAPKAPK2_ST	P04637	TP53	P49137	MAPKAPK2	S269	G266S	266	Missense	distal	-3	no	8.205	12.535	EPSD	COSMIC	11.681	Gain
CAMK_MAPKAPK_MK2_MAPKAPK2_ST	P04637	TP53	P49137	MAPKAPK2	T284	D281R	281	Missense	distal	-3	no	5.002	12.121	EPSD	COSMIC	11.681	Gain
CAMK_MAPKAPK_MK2_MAPKAPK2_ST	P04637	TP53	P49137	MAPKAPK2	T312	P309R	309	Missense	distal	-3	no	8.099	12.763	EPSD	COSMIC	11.681	Gain
CAMK_MAPKAPK_MK2_MAPKAPK2_ST	P04637	TP53	P49137	MAPKAPK2	S313	N310H	310	Missense	distal	-3	no	10.100	11.886	EPSD	COSMIC	11.681	Gain
CAMK_MAPKAPK_MK2_MAPKAPK2_ST	P04637	TP53	P49137	MAPKAPK2	S314	N310T	310	Missense	distal	-4	no	12.556	12.346	EPSD	COSMIC	11.681	Down-regulation
CAMK_MAPKAPK_MK2_MAPKAPK2_ST	P04637	TP53	P49137	MAPKAPK2	S314	Q317R	317	Missense	distal	3	no	12.556	12.652	EPSD	COSMIC	11.681	Up-regulation
CAMK_MAPKAPK_MK2_MAPKAPK2_ST	P04637	TP53	P49137	MAPKAPK2	S314	P309S	309	Missense	distal	-5	no	12.556	12.566	EPSD	COSMIC;GDSC;CCLE	11.681	Up-regulation
CAMK_MAPKAPK_MK2_MAPKAPK2_ST	P04637	TP53	P49137	MAPKAPK2	S314	K319E	319	Missense	distal	5	no	12.556	12.342	EPSD	COSMIC	11.681	Down-regulation
CAMK_MAPKAPK_MK2_MAPKAPK2_ST	P04637	TP53	P49137	MAPKAPK2	S314	K320N	320	Missense	distal	6	no	12.556	12.562	EPSD	COSMIC;GDSC;CCLE	11.681	Up-regulation
CAMK_MAPKAPK_MK2_MAPKAPK2_ST	P04637	TP53	P49137	MAPKAPK2	S314	N310L	310	Missense	distal	-4	no	12.556	12.538	EPSD	COSMIC	11.681	Down-regulation
CAMK_MAPKAPK_MK2_MAPKAPK2_ST	P04637	TP53	P49137	MAPKAPK2	S314	T312S	312	Missense	proximal	-2	no	12.556	14.310	EPSD	COSMIC	11.681	Up-regulation
CAMK_MAPKAPK_MK2_MAPKAPK2_ST	P04637	TP53	P49137	MAPKAPK2	S314	N311Y	311	Missense	distal	-3	no	12.556	13.360	EPSD	COSMIC	11.681	Up-regulation
CAMK_MAPKAPK_MK2_MAPKAPK2_ST	P04637	TP53	P49137	MAPKAPK2	S314	A307T	307	Missense	distal	-7	no	12.556	12.535	EPSD	COSMIC	11.681	Down-regulation
CAMK_MAPKAPK_MK2_MAPKAPK2_ST	P04637	TP53	P49137	MAPKAPK2	S314	N311K	311	Missense	distal	-3	no	12.556	13.977	EPSD	COSMIC	11.681	Up-regulation
CAMK_MAPKAPK_MK2_MAPKAPK2_ST	P04637	TP53	P49137	MAPKAPK2	S314	Q317K	317	Missense	distal	3	no	12.556	12.577	EPSD	COSMIC	11.681	Up-regulation
CAMK_MAPKAPK_MK2_MAPKAPK2_ST	P04637	TP53	P49137	MAPKAPK2	S314	S315P	315	Missense	proximal	1	no	12.556	12.666	EPSD	COSMIC	11.681	Up-regulation
CAMK_MAPKAPK_MK2_MAPKAPK2_ST	P04637	TP53	P49137	MAPKAPK2	S314	N310H	310	Missense	distal	-4	no	12.556	12.585	EPSD	COSMIC	11.681	Up-regulation
CAMK_MAPKAPK_MK2_MAPKAPK2_ST	P04637	TP53	P49137	MAPKAPK2	S314	S314C	314	Missense	central	0	yes	12.556	0.000	EPSD	COSMIC	11.681	Loss
CAMK_MAPKAPK_MK2_MAPKAPK2_ST	P04637	TP53	P49137	MAPKAPK2	S314	P318A	318	Missense	distal	4	no	12.556	12.637	EPSD	COSMIC	11.681	Up-regulation
CAMK_MAPKAPK_MK2_MAPKAPK2_ST	P04637	TP53	P49137	MAPKAPK2	S314	P316L	316	Missense	proximal	2	no	12.556	12.333	EPSD	COSMIC	11.681	Down-regulation
CAMK_MAPKAPK_MK2_MAPKAPK2_ST	P04637	TP53	P49137	MAPKAPK2	S314	L308M	308	Missense	distal	-6	no	12.556	12.565	EPSD	COSMIC	11.681	Up-regulation
CAMK_MAPKAPK_MK2_MAPKAPK2_ST	P04637	TP53	P49137	MAPKAPK2	S314	S313C	313	Missense	proximal	-1	no	12.556	12.566	EPSD	COSMIC	11.681	Up-regulation
CAMK_MAPKAPK_MK2_MAPKAPK2_ST	P04637	TP53	P49137	MAPKAPK2	S314	N311H	311	Missense	distal	-3	no	12.556	14.342	EPSD	COSMIC	11.681	Up-regulation
CAMK_MAPKAPK_MK2_MAPKAPK2_ST	P04637	TP53	P49137	MAPKAPK2	S314	L308V	308	Missense	distal	-6	no	12.556	12.568	EPSD	COSMIC	11.681	Up-regulation
CAMK_MAPKAPK_MK2_MAPKAPK2_ST	P04637	TP53	P49137	MAPKAPK2	S314	S314F	314	Missense	central	0	yes	12.556	0.000	EPSD	COSMIC	11.681	Loss
CAMK_MAPKAPK_MK2_MAPKAPK2_ST	P04637	TP53	P49137	MAPKAPK2	S314	K319R	319	Missense	distal	5	no	12.556	12.269	EPSD	COSMIC	11.681	Down-regulation
CAMK_MAPKAPK_MK2_MAPKAPK2_ST	P04637	TP53	P49137	MAPKAPK2	S314	T312A	312	Missense	proximal	-2	no	12.556	12.715	EPSD	COSMIC	11.681	Up-regulation
CAMK_MAPKAPK_MK2_MAPKAPK2_ST	P04637	TP53	P49137	MAPKAPK2	S314	N310D	310	Missense	distal	-4	no	12.556	12.594	EPSD	COSMIC	11.681	Up-regulation
CAMK_MAPKAPK_MK2_MAPKAPK2_ST	P04637	TP53	P49137	MAPKAPK2	S314	N311D	311	Missense	distal	-3	no	12.556	11.982	EPSD	COSMIC	11.681	Down-regulation
CAMK_MAPKAPK_MK2_MAPKAPK2_ST	P04637	TP53	P49137	MAPKAPK2	S314	P309R	309	Missense	distal	-5	no	12.556	12.719	EPSD	COSMIC	11.681	Up-regulation
CAMK_MAPKAPK_MK2_MAPKAPK2_ST	P04637	TP53	P49137	MAPKAPK2	S314	S313N	313	Missense	proximal	-1	no	12.556	12.571	EPSD	COSMIC	11.681	Up-regulation
CAMK_MAPKAPK_MK2_MAPKAPK2_ST	P04637	TP53	P49137	MAPKAPK2	S314	Q317P	317	Missense	distal	3	no	12.556	12.714	EPSD	COSMIC	11.681	Up-regulation
CAMK_MAPKAPK_MK2_MAPKAPK2_ST	P04637	TP53	P49137	MAPKAPK2	S314	A307S	307	Missense	distal	-7	no	12.556	12.565	EPSD	COSMIC	11.681	Up-regulation
CAMK_MAPKAPK_MK2_MAPKAPK2_ST	P04637	TP53	P49137	MAPKAPK2	S314	P316S	316	Missense	proximal	2	no	12.556	12.748	EPSD	COSMIC	11.681	Up-regulation
CAMK_MAPKAPK_MK2_MAPKAPK2_ST	P04637	TP53	P49137	MAPKAPK2	S315	N310T	310	Missense	distal	-5	no	12.896	13.511	EPSD	COSMIC	11.681	Up-regulation
CAMK_MAPKAPK_MK2_MAPKAPK2_ST	P04637	TP53	P49137	MAPKAPK2	S315	Q317R	317	Missense	proximal	2	no	12.896	13.200	EPSD	COSMIC	11.681	Up-regulation
CAMK_MAPKAPK_MK2_MAPKAPK2_ST	P04637	TP53	P49137	MAPKAPK2	S315	P309S	309	Missense	distal	-6	no	12.896	12.895	EPSD	COSMIC;GDSC;CCLE	11.681	Down-regulation
CAMK_MAPKAPK_MK2_MAPKAPK2_ST	P04637	TP53	P49137	MAPKAPK2	S315	K319E	319	Missense	distal	4	no	12.896	13.077	EPSD	COSMIC	11.681	Up-regulation
CAMK_MAPKAPK_MK2_MAPKAPK2_ST	P04637	TP53	P49137	MAPKAPK2	S315	P322L	322	Missense	distal	7	no	12.896	12.422	EPSD	COSMIC	11.681	Down-regulation
CAMK_MAPKAPK_MK2_MAPKAPK2_ST	P04637	TP53	P49137	MAPKAPK2	S315	K320N	320	Missense	distal	5	no	12.896	12.830	EPSD	COSMIC;GDSC;CCLE	11.681	Down-regulation
CAMK_MAPKAPK_MK2_MAPKAPK2_ST	P04637	TP53	P49137	MAPKAPK2	S315	N310L	310	Missense	distal	-5	no	12.896	14.087	EPSD	COSMIC	11.681	Up-regulation
CAMK_MAPKAPK_MK2_MAPKAPK2_ST	P04637	TP53	P49137	MAPKAPK2	S315	T312S	312	Missense	distal	-3	no	12.896	12.441	EPSD	COSMIC	11.681	Down-regulation
CAMK_MAPKAPK_MK2_MAPKAPK2_ST	P04637	TP53	P49137	MAPKAPK2	S315	N311Y	311	Missense	distal	-4	no	12.896	13.018	EPSD	COSMIC	11.681	Up-regulation
CAMK_MAPKAPK_MK2_MAPKAPK2_ST	P04637	TP53	P49137	MAPKAPK2	S315	P322R	322	Missense	distal	7	no	12.896	12.807	EPSD	COSMIC	11.681	Down-regulation
CAMK_MAPKAPK_MK2_MAPKAPK2_ST	P04637	TP53	P49137	MAPKAPK2	S315	N311K	311	Missense	distal	-4	no	12.896	12.930	EPSD	COSMIC	11.681	Up-regulation
CAMK_MAPKAPK_MK2_MAPKAPK2_ST	P04637	TP53	P49137	MAPKAPK2	S315	Q317K	317	Missense	proximal	2	no	12.896	12.797	EPSD	COSMIC	11.681	Down-regulation
CAMK_MAPKAPK_MK2_MAPKAPK2_ST	P04637	TP53	P49137	MAPKAPK2	S315	S315P	315	Missense	central	0	yes	12.896	0.000	EPSD	COSMIC	11.681	Loss
CAMK_MAPKAPK_MK2_MAPKAPK2_ST	P04637	TP53	P49137	MAPKAPK2	S315	N310H	310	Missense	distal	-5	no	12.896	13.269	EPSD	COSMIC	11.681	Up-regulation
CAMK_MAPKAPK_MK2_MAPKAPK2_ST	P04637	TP53	P49137	MAPKAPK2	S315	S314C	314	Missense	proximal	-1	no	12.896	12.906	EPSD	COSMIC	11.681	Up-regulation
CAMK_MAPKAPK_MK2_MAPKAPK2_ST	P04637	TP53	P49137	MAPKAPK2	S315	P318A	318	Missense	distal	3	no	12.896	12.947	EPSD	COSMIC	11.681	Up-regulation
CAMK_MAPKAPK_MK2_MAPKAPK2_ST	P04637	TP53	P49137	MAPKAPK2	S315	P316L	316	Missense	proximal	1	no	12.896	12.986	EPSD	COSMIC	11.681	Up-regulation
CAMK_MAPKAPK_MK2_MAPKAPK2_ST	P04637	TP53	P49137	MAPKAPK2	S315	L308M	308	Missense	distal	-7	no	12.896	12.893	EPSD	COSMIC	11.681	Down-regulation
CAMK_MAPKAPK_MK2_MAPKAPK2_ST	P04637	TP53	P49137	MAPKAPK2	S315	S313C	313	Missense	proximal	-2	no	12.896	9.417	EPSD	COSMIC	11.681	Loss
CAMK_MAPKAPK_MK2_MAPKAPK2_ST	P04637	TP53	P49137	MAPKAPK2	S315	N311H	311	Missense	distal	-4	no	12.896	12.925	EPSD	COSMIC	11.681	Up-regulation
CAMK_MAPKAPK_MK2_MAPKAPK2_ST	P04637	TP53	P49137	MAPKAPK2	S315	L308V	308	Missense	distal	-7	no	12.896	12.898	EPSD	COSMIC	11.681	Up-regulation
CAMK_MAPKAPK_MK2_MAPKAPK2_ST	P04637	TP53	P49137	MAPKAPK2	S315	S314F	314	Missense	proximal	-1	no	12.896	12.912	EPSD	COSMIC	11.681	Up-regulation
CAMK_MAPKAPK_MK2_MAPKAPK2_ST	P04637	TP53	P49137	MAPKAPK2	S315	K319R	319	Missense	distal	4	no	12.896	13.071	EPSD	COSMIC	11.681	Up-regulation
CAMK_MAPKAPK_MK2_MAPKAPK2_ST	P04637	TP53	P49137	MAPKAPK2	S315	T312A	312	Missense	distal	-3	no	12.896	9.550	EPSD	COSMIC	11.681	Loss
CAMK_MAPKAPK_MK2_MAPKAPK2_ST	P04637	TP53	P49137	MAPKAPK2	S315	N310D	310	Missense	distal	-5	no	12.896	12.817	EPSD	COSMIC	11.681	Down-regulation
CAMK_MAPKAPK_MK2_MAPKAPK2_ST	P04637	TP53	P49137	MAPKAPK2	S315	N311D	311	Missense	distal	-4	no	12.896	12.934	EPSD	COSMIC	11.681	Up-regulation
CAMK_MAPKAPK_MK2_MAPKAPK2_ST	P04637	TP53	P49137	MAPKAPK2	S315	P309R	309	Missense	distal	-6	no	12.896	12.908	EPSD	COSMIC	11.681	Up-regulation
CAMK_MAPKAPK_MK2_MAPKAPK2_ST	P04637	TP53	P49137	MAPKAPK2	S315	S313N	313	Missense	proximal	-2	no	12.896	10.531	EPSD	COSMIC	11.681	Loss
CAMK_MAPKAPK_MK2_MAPKAPK2_ST	P04637	TP53	P49137	MAPKAPK2	S315	Q317P	317	Missense	proximal	2	no	12.896	13.112	EPSD	COSMIC	11.681	Up-regulation
CAMK_MAPKAPK_MK2_MAPKAPK2_ST	P04637	TP53	P49137	MAPKAPK2	S315	P316S	316	Missense	proximal	1	no	12.896	12.785	EPSD	COSMIC	11.681	Down-regulation
CAMK_MAPKAPK_MK2_MAPKAPK2_ST	P04637	TP53	P49137	MAPKAPK2	S362	G360A	360	Missense	proximal	-2	no	10.794	12.536	EPSD	COSMIC	11.681	Gain
CAMK_MAPKAPK_MK2_MAPKAPK2_ST	P04637	TP53	P49137	MAPKAPK2	S366	S367F	367	Missense	proximal	1	no	15.431	15.188	EPSD	COSMIC	11.681	Down-regulation
CAMK_MAPKAPK_MK2_MAPKAPK2_ST	P04637	TP53	P49137	MAPKAPK2	S366	K370N	370	Missense	distal	4	no	15.431	15.476	EPSD	COSMIC	11.681	Up-regulation
CAMK_MAPKAPK_MK2_MAPKAPK2_ST	P04637	TP53	P49137	MAPKAPK2	S366	G361E	361	Missense	distal	-5	no	15.431	16.259	EPSD	COSMIC	11.681	Up-regulation
CAMK_MAPKAPK_MK2_MAPKAPK2_ST	P04637	TP53	P49137	MAPKAPK2	S366	P359S	359	Missense	distal	-7	no	15.431	15.433	EPSD	COSMIC	11.681	Up-regulation
CAMK_MAPKAPK_MK2_MAPKAPK2_ST	P04637	TP53	P49137	MAPKAPK2	S366	A364D	364	Missense	proximal	-2	no	15.431	12.666	EPSD	COSMIC	11.681	Down-regulation
CAMK_MAPKAPK_MK2_MAPKAPK2_ST	P04637	TP53	P49137	MAPKAPK2	S366	H365Y	365	Missense	proximal	-1	no	15.431	15.437	EPSD	COSMIC	11.681	Up-regulation
CAMK_MAPKAPK_MK2_MAPKAPK2_ST	P04637	TP53	P49137	MAPKAPK2	S366	G360A	360	Missense	distal	-6	no	15.431	15.361	EPSD	COSMIC	11.681	Down-regulation
CAMK_MAPKAPK_MK2_MAPKAPK2_ST	P04637	TP53	P49137	MAPKAPK2	S366	A364T	364	Missense	proximal	-2	no	15.431	15.271	EPSD	COSMIC	11.681	Down-regulation
CAMK_MAPKAPK_MK2_MAPKAPK2_ST	P04637	TP53	P49137	MAPKAPK2	S366	S366A	366	Missense	central	0	yes	15.431	0.000	EPSD	COSMIC	11.681	Loss
CAMK_MAPKAPK_MK2_MAPKAPK2_ST	P04637	TP53	P49137	MAPKAPK2	S366	G361R	361	Missense	distal	-5	no	15.431	16.463	EPSD	COSMIC	11.681	Up-regulation
CAMK_MAPKAPK_MK2_MAPKAPK2_ST	P04637	TP53	P49137	MAPKAPK2	S366	K370Q	370	Missense	distal	4	no	15.431	15.470	EPSD	COSMIC	11.681	Up-regulation
CAMK_MAPKAPK_MK2_MAPKAPK2_ST	P04637	TP53	P49137	MAPKAPK2	S366	K373R	373	Missense	distal	7	no	15.431	15.654	EPSD	COSMIC	11.681	Up-regulation
CAMK_MAPKAPK_MK2_MAPKAPK2_ST	P04637	TP53	P49137	MAPKAPK2	S366	S371P	371	Missense	distal	5	no	15.431	15.513	EPSD	COSMIC	11.681	Up-regulation
CAMK_MAPKAPK_MK2_MAPKAPK2_ST	P04637	TP53	P49137	MAPKAPK2	S376	K373R	373	Missense	distal	-3	no	11.584	16.709	EPSD	COSMIC	11.681	Gain
CAMK_MAPKAPK_MK2_MAPKAPK2_ST	P04637	TP53	P49137	MAPKAPK2	S376	G374S	374	Missense	proximal	-2	no	11.584	14.922	EPSD	COSMIC	11.681	Gain
CAMK_MAPKAPK_MK2_MAPKAPK2_ST	P04637	TP53	P49137	MAPKAPK2	S378	L383F	383	Missense	distal	5	no	13.171	13.390	EPSD	COSMIC	11.681	Up-regulation
CAMK_MAPKAPK_MK2_MAPKAPK2_ST	P04637	TP53	P49137	MAPKAPK2	S378	R379H	379	Missense	proximal	1	no	13.171	12.782	EPSD	COSMIC	11.681	Down-regulation
CAMK_MAPKAPK_MK2_MAPKAPK2_ST	P04637	TP53	P49137	MAPKAPK2	S378	S376T	376	Missense	proximal	-2	no	13.171	11.417	EPSD	COSMIC	11.681	Loss
CAMK_MAPKAPK_MK2_MAPKAPK2_ST	P04637	TP53	P49137	MAPKAPK2	S378	H380Y	380	Missense	proximal	2	no	13.171	13.096	EPSD	COSMIC	11.681	Down-regulation
CAMK_MAPKAPK_MK2_MAPKAPK2_ST	P04637	TP53	P49137	MAPKAPK2	S378	T377I	377	Missense	proximal	-1	no	13.171	13.177	EPSD	COSMIC	11.681	Up-regulation
CAMK_MAPKAPK_MK2_MAPKAPK2_ST	P04637	TP53	P49137	MAPKAPK2	S378	S378F	378	Missense	central	0	yes	13.171	0.000	EPSD	COSMIC	11.681	Loss
CAMK_MAPKAPK_MK2_MAPKAPK2_ST	P04637	TP53	P49137	MAPKAPK2	S378	K381N	381	Missense	distal	3	no	13.171	13.158	EPSD	COSMIC	11.681	Down-regulation
CAMK_MAPKAPK_MK2_MAPKAPK2_ST	P04637	TP53	P49137	MAPKAPK2	S378	R379P	379	Missense	proximal	1	no	13.171	13.258	EPSD	COSMIC	11.681	Up-regulation
CAMK_MAPKAPK_MK2_MAPKAPK2_ST	P04637	TP53	P49137	MAPKAPK2	S378	M384I	384	Missense	distal	6	no	13.171	13.163	EPSD	COSMIC	11.681	Down-regulation
CAMK_MAPKAPK_MK2_MAPKAPK2_ST	P04637	TP53	P49137	MAPKAPK2	S378	K373R	373	Missense	distal	-5	no	13.171	13.983	EPSD	COSMIC	11.681	Up-regulation
CAMK_MAPKAPK_MK2_MAPKAPK2_ST	P04637	TP53	P49137	MAPKAPK2	S378	S376F	376	Missense	proximal	-2	no	13.171	7.745	EPSD	COSMIC	11.681	Loss
CAMK_MAPKAPK_MK2_MAPKAPK2_ST	P04637	TP53	P49137	MAPKAPK2	S378	G374S	374	Missense	distal	-4	no	13.171	12.834	EPSD	COSMIC	11.681	Down-regulation
CAMK_MAPKAPK_MK2_MAPKAPK2_ST	P04637	TP53	P49137	MAPKAPK2	S378	S376A	376	Missense	proximal	-2	no	13.171	11.576	EPSD	COSMIC	11.681	Loss
CAMK_MAPKAPK_MK2_MAPKAPK2_ST	P04637	TP53	P49137	MAPKAPK2	S378	S371P	371	Missense	distal	-7	no	13.171	13.169	EPSD	COSMIC	11.681	Down-regulation
CAMK_MAPKAPK_MK2_MAPKAPK2_ST	Q14134	TRIM29	P49137	MAPKAPK2	S21	D18N	18	Missense	distal	-3	no	12.763	13.336	EPSD	COSMIC	11.681	Up-regulation
CAMK_MAPKAPK_MK2_MAPKAPK2_ST	Q14134	TRIM29	P49137	MAPKAPK2	S21	S21L	21	Missense	central	0	yes	12.763	0.000	EPSD	COSMIC	11.681	Loss
CAMK_MAPKAPK_MK2_MAPKAPK2_ST	Q14134	TRIM29	P49137	MAPKAPK2	S21	E15G	15	Missense	distal	-6	no	12.763	12.841	EPSD	COSMIC	11.681	Up-regulation
CAMK_MAPKAPK_MK2_MAPKAPK2_ST	Q14134	TRIM29	P49137	MAPKAPK2	S23	G27D	27	Missense	distal	4	no	18.844	18.839	EPSD	COSMIC	11.681	Down-regulation
CAMK_MAPKAPK_MK2_MAPKAPK2_ST	Q14134	TRIM29	P49137	MAPKAPK2	S23	E30K	30	Missense	distal	7	no	18.844	18.572	EPSD	COSMIC;GDSC	11.681	Down-regulation
CAMK_MAPKAPK_MK2_MAPKAPK2_ST	Q14134	TRIM29	P49137	MAPKAPK2	S23	D18N	18	Missense	distal	-5	no	18.844	18.923	EPSD	COSMIC	11.681	Up-regulation
CAMK_MAPKAPK_MK2_MAPKAPK2_ST	Q14134	TRIM29	P49137	MAPKAPK2	S23	S21L	21	Missense	proximal	-2	no	18.844	15.487	EPSD	COSMIC	11.681	Down-regulation
CAMK_MAPKAPK_MK2_MAPKAPK2_ST	Q14134	TRIM29	P49137	MAPKAPK2	S28	G27D	27	Missense	proximal	-1	no	16.012	16.007	EPSD	COSMIC	11.681	Down-regulation
CAMK_MAPKAPK_MK2_MAPKAPK2_ST	Q14134	TRIM29	P49137	MAPKAPK2	S28	E30K	30	Missense	proximal	2	no	16.012	15.713	EPSD	COSMIC;GDSC	11.681	Down-regulation
CAMK_MAPKAPK_MK2_MAPKAPK2_ST	Q14134	TRIM29	P49137	MAPKAPK2	S28	G32D	32	Missense	distal	4	no	16.012	16.006	EPSD	COSMIC	11.681	Down-regulation
CAMK_MAPKAPK_MK2_MAPKAPK2_ST	Q14134	TRIM29	P49137	MAPKAPK2	S28	S21L	21	Missense	distal	-7	no	16.012	16.044	EPSD	COSMIC	11.681	Up-regulation
CAMK_MAPKAPK_MK2_MAPKAPK2_ST	Q14134	TRIM29	P49137	MAPKAPK2	S67	G65N	65	Missense	proximal	-2	no	11.067	12.040	EPSD	COSMIC	11.681	Gain
CAMK_MAPKAPK_MK2_MAPKAPK2_ST	Q14134	TRIM29	P49137	MAPKAPK2	S141	M143I	143	Missense	proximal	2	no	12.305	12.156	EPSD	COSMIC	11.681	Down-regulation
CAMK_MAPKAPK_MK2_MAPKAPK2_ST	Q14134	TRIM29	P49137	MAPKAPK2	S152	R155H	155	Missense	distal	3	no	17.151	17.014	EPSD	COSMIC	11.681	Down-regulation
CAMK_MAPKAPK_MK2_MAPKAPK2_ST	Q14134	TRIM29	P49137	MAPKAPK2	T158	R155H	155	Missense	distal	-3	no	13.302	8.542	EPSD	COSMIC	11.681	Loss
CAMK_MAPKAPK_MK2_MAPKAPK2_ST	Q14134	TRIM29	P49137	MAPKAPK2	T158	R163W	163	Missense	distal	5	no	13.302	13.521	EPSD	COSMIC	11.681	Up-regulation
CAMK_MAPKAPK_MK2_MAPKAPK2_ST	Q14134	TRIM29	P49137	MAPKAPK2	T158	S162L	162	Missense	distal	4	no	13.302	13.149	EPSD	COSMIC	11.681	Down-regulation
CAMK_MAPKAPK_MK2_MAPKAPK2_ST	Q14134	TRIM29	P49137	MAPKAPK2	S166	R163W	163	Missense	distal	-3	no	19.687	11.108	EPSD	COSMIC	11.681	Loss
CAMK_MAPKAPK_MK2_MAPKAPK2_ST	Q14134	TRIM29	P49137	MAPKAPK2	S166	E169K	169	Missense	distal	3	no	19.687	19.560	EPSD	COSMIC	11.681	Down-regulation
CAMK_MAPKAPK_MK2_MAPKAPK2_ST	Q14134	TRIM29	P49137	MAPKAPK2	S166	S168P	168	Missense	proximal	2	no	19.687	19.495	EPSD	COSMIC	11.681	Down-regulation
CAMK_MAPKAPK_MK2_MAPKAPK2_ST	Q14134	TRIM29	P49137	MAPKAPK2	S166	S162L	162	Missense	distal	-4	no	19.687	19.891	EPSD	COSMIC	11.681	Up-regulation
CAMK_MAPKAPK_MK2_MAPKAPK2_ST	Q14134	TRIM29	P49137	MAPKAPK2	S168	R163W	163	Missense	distal	-5	no	14.034	13.680	EPSD	COSMIC	11.681	Down-regulation
CAMK_MAPKAPK_MK2_MAPKAPK2_ST	Q14134	TRIM29	P49137	MAPKAPK2	S168	E169K	169	Missense	proximal	1	no	14.034	13.570	EPSD	COSMIC	11.681	Down-regulation
CAMK_MAPKAPK_MK2_MAPKAPK2_ST	Q14134	TRIM29	P49137	MAPKAPK2	S168	S168P	168	Missense	central	0	yes	14.034	0.000	EPSD	COSMIC	11.681	Loss
CAMK_MAPKAPK_MK2_MAPKAPK2_ST	Q14134	TRIM29	P49137	MAPKAPK2	S168	S162L	162	Missense	distal	-6	no	14.034	14.066	EPSD	COSMIC	11.681	Up-regulation
CAMK_MAPKAPK_MK2_MAPKAPK2_ST	Q14134	TRIM29	P49137	MAPKAPK2	S301	S301F	301	Missense	central	0	yes	14.704	0.000	EPSD	COSMIC	11.681	Loss
CAMK_MAPKAPK_MK2_MAPKAPK2_ST	Q14134	TRIM29	P49137	MAPKAPK2	S472	P477S	477	Missense	distal	5	no	12.203	12.120	EPSD	COSMIC	11.681	Down-regulation
CAMK_MAPKAPK_MK2_MAPKAPK2_ST	Q14134	TRIM29	P49137	MAPKAPK2	S472	G479C	479	Missense	distal	7	no	12.203	12.182	EPSD	COSMIC	11.681	Down-regulation
CAMK_MAPKAPK_MK2_MAPKAPK2_ST	Q14134	TRIM29	P49137	MAPKAPK2	S537	Q534H	534	Missense	distal	-3	no	10.937	11.942	EPSD	COSMIC	11.681	Gain
CAMK_MAPKAPK_MK2_MAPKAPK2_ST	Q14134	TRIM29	P49137	MAPKAPK2	S550	R549L	549	Missense	proximal	-1	no	13.078	13.089	PhosphoSitePlus;EPSD	COSMIC	11.681	Up-regulation
CAMK_MAPKAPK_MK2_MAPKAPK2_ST	Q14134	TRIM29	P49137	MAPKAPK2	S550	Y544C	544	Missense	distal	-6	no	13.078	13.038	PhosphoSitePlus;EPSD	COSMIC	11.681	Down-regulation
CAMK_MAPKAPK_MK2_MAPKAPK2_ST	Q14134	TRIM29	P49137	MAPKAPK2	S550	P553L	553	Missense	distal	3	no	13.078	12.969	PhosphoSitePlus;EPSD	COSMIC	11.681	Down-regulation
CAMK_MAPKAPK_MK2_MAPKAPK2_ST	Q14134	TRIM29	P49137	MAPKAPK2	S552	R549L	549	Missense	distal	-3	no	19.038	13.948	EPSD;PhosphoSitePlus	COSMIC	11.681	Down-regulation
CAMK_MAPKAPK_MK2_MAPKAPK2_ST	Q14134	TRIM29	P49137	MAPKAPK2	S552	T559A	559	Missense	distal	7	no	19.038	18.937	EPSD;PhosphoSitePlus	COSMIC	11.681	Down-regulation
CAMK_MAPKAPK_MK2_MAPKAPK2_ST	Q14134	TRIM29	P49137	MAPKAPK2	S552	P553L	553	Missense	proximal	1	no	19.038	19.129	EPSD;PhosphoSitePlus	COSMIC	11.681	Up-regulation
CAMK_MAPKAPK_MK2_MAPKAPK2_ST	P09917	ALOX5	P49137	MAPKAPK2	S272	L267M	267	Missense	distal	-5	no	17.029	16.273	EPSD;PhosphoSitePlus	COSMIC	11.681	Down-regulation
CAMK_MAPKAPK_MK2_MAPKAPK2_ST	O95453	PARN	P49137	MAPKAPK2	S167	Y161D	161	Missense	distal	-6	no	12.562	12.523	EPSD	COSMIC;CCLE	11.681	Down-regulation
CAMK_MAPKAPK_MK2_MAPKAPK2_ST	O95453	PARN	P49137	MAPKAPK2	S167	N165K	165	Missense	proximal	-2	no	12.562	10.485	EPSD	COSMIC	11.681	Loss
CAMK_MAPKAPK_MK2_MAPKAPK2_ST	O95453	PARN	P49137	MAPKAPK2	S342	A344V	344	Missense	proximal	2	no	12.180	11.875	EPSD	COSMIC;GDSC;CCLE	11.681	Down-regulation
CAMK_MAPKAPK_MK2_MAPKAPK2_ST	O95453	PARN	P49137	MAPKAPK2	S342	I338T	338	Missense	distal	-4	no	12.180	12.048	EPSD	COSMIC	11.681	Down-regulation
CAMK_MAPKAPK_MK2_MAPKAPK2_ST	O95453	PARN	P49137	MAPKAPK2	S342	E347K	347	Missense	distal	5	no	12.180	12.394	EPSD	COSMIC	11.681	Up-regulation
CAMK_MAPKAPK_MK2_MAPKAPK2_ST	O95453	PARN	P49137	MAPKAPK2	S342	D336N	336	Missense	distal	-6	no	12.180	12.188	EPSD	COSMIC	11.681	Up-regulation
CAMK_MAPKAPK_MK2_MAPKAPK2_ST	O95453	PARN	P49137	MAPKAPK2	T527	W526L	526	Missense	proximal	-1	no	12.253	12.245	EPSD	COSMIC	11.681	Down-regulation
CAMK_MAPKAPK_MK2_MAPKAPK2_ST	O95453	PARN	P49137	MAPKAPK2	T527	W526R	526	Missense	proximal	-1	no	12.253	12.235	EPSD	COSMIC	11.681	Down-regulation
CAMK_MAPKAPK_MK2_MAPKAPK2_ST	O95453	PARN	P49137	MAPKAPK2	S557	R554C	554	Missense	distal	-3	no	16.300	7.900	PhosphoSitePlus	COSMIC	11.681	Loss
CAMK_MAPKAPK_MK2_MAPKAPK2_ST	O95453	PARN	P49137	MAPKAPK2	S557	A560V	560	Missense	distal	3	no	16.300	16.195	PhosphoSitePlus	COSMIC	11.681	Down-regulation
CAMK_MAPKAPK_MK2_MAPKAPK2_ST	O95453	PARN	P49137	MAPKAPK2	S557	V564I	564	Missense	distal	7	no	16.300	16.260	PhosphoSitePlus	COSMIC	11.681	Down-regulation
CAMK_MAPKAPK_MK2_MAPKAPK2_ST	O95453	PARN	P49137	MAPKAPK2	S557	S557N	557	Missense	central	0	yes	16.300	0.000	PhosphoSitePlus	COSMIC	11.681	Loss
CAMK_MAPKAPK_MK2_MAPKAPK2_ST	O95453	PARN	P49137	MAPKAPK2	S570	V564I	564	Missense	distal	-6	no	15.897	15.892	EPSD	COSMIC	11.681	Down-regulation
CAMK_MAPKAPK_MK2_MAPKAPK2_ST	O95453	PARN	P49137	MAPKAPK2	S623	N627Y	627	Missense	distal	4	no	13.123	12.963	EPSD	COSMIC	11.681	Down-regulation
CAMK_MAPKAPK_MK2_MAPKAPK2_ST	P17844	DDX5	P49137	MAPKAPK2	S198	A193T	193	Missense	distal	-5	no	13.931	14.333	PhosphoSitePlus	COSMIC	11.681	Up-regulation
CAMK_MAPKAPK_MK2_MAPKAPK2_ST	P17844	DDX5	P49137	MAPKAPK2	S198	L196V	196	Missense	proximal	-2	no	13.931	13.492	PhosphoSitePlus	COSMIC	11.681	Down-regulation
CAMK_MAPKAPK_MK2_MAPKAPK2_ST	P17844	DDX5	P49137	MAPKAPK2	S519	D525Y	525	Missense	distal	6	no	13.223	13.214	EPSD	COSMIC	11.681	Down-regulation
CAMK_MAPKAPK_MK2_MAPKAPK2_ST	P17844	DDX5	P49137	MAPKAPK2	S519	Y514H	514	Missense	distal	-5	no	13.223	13.719	EPSD	COSMIC	11.681	Up-regulation
CAMK_MAPKAPK_MK2_MAPKAPK2_ST	Q92904	DAZL	P49137	MAPKAPK2	S14	S18C	18	Missense	distal	4	no	11.770	11.593	EPSD	COSMIC	11.681	Loss
CAMK_MAPKAPK_MK2_MAPKAPK2_ST	Q92904	DAZL	P49137	MAPKAPK2	S14	R15T	15	Missense	proximal	1	no	11.770	11.892	EPSD	COSMIC	11.681	Up-regulation
CAMK_MAPKAPK_MK2_MAPKAPK2_ST	Q92904	DAZL	P49137	MAPKAPK2	S65	V69A	69	Missense	distal	4	no	14.833	14.983	PhosphoSitePlus	COSMIC	11.681	Up-regulation
CAMK_MAPKAPK_MK2_MAPKAPK2_ST	Q92904	DAZL	P49137	MAPKAPK2	S65	V66L	66	Missense	proximal	1	no	14.833	14.844	PhosphoSitePlus	COSMIC	11.681	Up-regulation
CAMK_MAPKAPK_MK2_MAPKAPK2_ST	Q92904	DAZL	P49137	MAPKAPK2	S65	I71T	71	Missense	distal	6	no	14.833	14.856	PhosphoSitePlus	COSMIC	11.681	Up-regulation
CAMK_MAPKAPK_MK2_MAPKAPK2_ST	Q13546	RIPK1	P49137	MAPKAPK2	S320	A313T	313	Missense	distal	-7	no	17.125	17.104	PhosphoSitePlus	COSMIC	11.681	Down-regulation
CAMK_MAPKAPK_MK2_MAPKAPK2_ST	Q13546	RIPK1	P49137	MAPKAPK2	S320	V326L	326	Missense	distal	6	no	17.125	17.128	PhosphoSitePlus	COSMIC;GDSC;CCLE	11.681	Up-regulation
CAMK_MAPKAPK_MK2_MAPKAPK2_ST	Q13546	RIPK1	P49137	MAPKAPK2	S416	A421V	421	Missense	distal	5	no	14.768	14.912	EPSD	COSMIC	11.681	Up-regulation
CAMK_MAPKAPK_MK2_MAPKAPK2_ST	P11831	SRF	P49137	MAPKAPK2	S251	T244P	244	Missense	distal	-7	no	12.468	12.496	EPSD	COSMIC;GDSC;CCLE	11.681	Up-regulation
CAMK_MAPKAPK_MK2_MAPKAPK2_ST	P11831	SRF	P49137	MAPKAPK2	S251	V250M	250	Missense	proximal	-1	no	12.468	12.474	EPSD	COSMIC	11.681	Up-regulation
CAMK_MAPKAPK_MK2_MAPKAPK2_ST	P11831	SRF	P49137	MAPKAPK2	S435	V430M	430	Missense	distal	-5	no	12.240	11.792	EPSD	COSMIC	11.681	Down-regulation
CAMK_MAPKAPK_MK2_MAPKAPK2_ST	P11831	SRF	P49137	MAPKAPK2	S435	T429I	429	Missense	distal	-6	no	12.240	12.294	EPSD	COSMIC	11.681	Up-regulation
CAMK_MAPKAPK_MK2_MAPKAPK2_ST	P11831	SRF	P49137	MAPKAPK2	S435	A433T	433	Missense	proximal	-2	no	12.240	12.080	EPSD	COSMIC	11.681	Down-regulation
CAMK_MAPKAPK_MK2_MAPKAPK2_ST	P11831	SRF	P49137	MAPKAPK2	S435	A433V	433	Missense	proximal	-2	no	12.240	10.039	EPSD	COSMIC	11.681	Loss
CAMK_MAPKAPK_MK2_MAPKAPK2_ST	P11831	SRF	P49137	MAPKAPK2	S435	A437S	437	Missense	proximal	2	no	12.240	12.269	EPSD	COSMIC	11.681	Up-regulation
CAMK_MAPKAPK_MK2_MAPKAPK2_ST	Q13263	TRIM28	P49137	MAPKAPK2	S37	T34P	34	Missense	distal	-3	no	12.267	13.478	EPSD	COSMIC	11.681	Up-regulation
CAMK_MAPKAPK_MK2_MAPKAPK2_ST	Q13263	TRIM28	P49137	MAPKAPK2	S37	A38T	38	Missense	proximal	1	no	12.267	12.473	EPSD	COSMIC	11.681	Up-regulation
CAMK_MAPKAPK_MK2_MAPKAPK2_ST	Q13263	TRIM28	P49137	MAPKAPK2	S41	A38T	38	Missense	distal	-3	no	9.307	12.652	EPSD	COSMIC	11.681	Gain
CAMK_MAPKAPK_MK2_MAPKAPK2_ST	Q13263	TRIM28	P49137	MAPKAPK2	S43	A38T	38	Missense	distal	-5	no	11.362	11.765	EPSD	COSMIC	11.681	Gain
CAMK_MAPKAPK_MK2_MAPKAPK2_ST	Q13263	TRIM28	P49137	MAPKAPK2	S285	R282H	282	Missense	distal	-3	no	16.286	11.527	EPSD	COSMIC	11.681	Loss
CAMK_MAPKAPK_MK2_MAPKAPK2_ST	Q13263	TRIM28	P49137	MAPKAPK2	S285	D286E	286	Missense	proximal	1	no	16.286	16.720	EPSD	COSMIC	11.681	Up-regulation
CAMK_MAPKAPK_MK2_MAPKAPK2_ST	Q13263	TRIM28	P49137	MAPKAPK2	S285	K289Q	289	Missense	distal	4	no	16.286	16.325	EPSD	COSMIC	11.681	Up-regulation
CAMK_MAPKAPK_MK2_MAPKAPK2_ST	Q13263	TRIM28	P49137	MAPKAPK2	S437	S437F	437	Missense	central	0	yes	11.763	0.000	EPSD	COSMIC	11.681	Loss
CAMK_MAPKAPK_MK2_MAPKAPK2_ST	Q13263	TRIM28	P49137	MAPKAPK2	S437	P442L	442	Missense	distal	5	no	11.763	11.850	EPSD	COSMIC;GDSC	11.681	Up-regulation
CAMK_MAPKAPK_MK2_MAPKAPK2_ST	Q13263	TRIM28	P49137	MAPKAPK2	S473	E477D	477	Missense	distal	4	no	19.200	19.064	PhosphoSitePlus	COSMIC	11.681	Down-regulation
CAMK_MAPKAPK_MK2_MAPKAPK2_ST	Q13263	TRIM28	P49137	MAPKAPK2	S473	G467D	467	Missense	distal	-6	no	19.200	19.180	PhosphoSitePlus	COSMIC	11.681	Down-regulation
CAMK_MAPKAPK_MK2_MAPKAPK2_ST	Q13263	TRIM28	P49137	MAPKAPK2	S473	R472S	472	Missense	proximal	-1	no	19.200	19.210	PhosphoSitePlus	COSMIC	11.681	Up-regulation
CAMK_MAPKAPK_MK2_MAPKAPK2_ST	Q13263	TRIM28	P49137	MAPKAPK2	S473	G476C	476	Missense	distal	3	no	19.200	19.181	PhosphoSitePlus	COSMIC	11.681	Down-regulation
CAMK_MAPKAPK_MK2_MAPKAPK2_ST	Q13263	TRIM28	P49137	MAPKAPK2	S473	G480V	480	Missense	distal	7	no	19.200	19.181	PhosphoSitePlus	COSMIC	11.681	Down-regulation
CAMK_MAPKAPK_MK2_MAPKAPK2_ST	Q13263	TRIM28	P49137	MAPKAPK2	S489	R492L	492	Missense	distal	3	no	13.101	13.054	EPSD	COSMIC	11.681	Down-regulation
CAMK_MAPKAPK_MK2_MAPKAPK2_ST	Q13263	TRIM28	P49137	MAPKAPK2	S501	D500H	500	Missense	proximal	-1	no	12.041	12.040	EPSD	COSMIC	11.681	Down-regulation
CAMK_MAPKAPK_MK2_MAPKAPK2_ST	Q13263	TRIM28	P49137	MAPKAPK2	S594	R591L	591	Missense	distal	-3	no	14.830	9.740	EPSD	COSMIC	11.681	Loss
CAMK_MAPKAPK_MK2_MAPKAPK2_ST	Q13263	TRIM28	P49137	MAPKAPK2	S594	P590L	590	Missense	distal	-4	no	14.830	14.955	EPSD	COSMIC	11.681	Up-regulation
CAMK_MAPKAPK_MK2_MAPKAPK2_ST	Q13263	TRIM28	P49137	MAPKAPK2	S594	R591C	591	Missense	distal	-3	no	14.830	6.431	EPSD	COSMIC	11.681	Loss
CAMK_MAPKAPK_MK2_MAPKAPK2_ST	Q13263	TRIM28	P49137	MAPKAPK2	S598	R591L	591	Missense	distal	-7	no	14.103	14.170	EPSD	COSMIC	11.681	Up-regulation
CAMK_MAPKAPK_MK2_MAPKAPK2_ST	Q13263	TRIM28	P49137	MAPKAPK2	S598	R591C	591	Missense	distal	-7	no	14.103	14.183	EPSD	COSMIC	11.681	Up-regulation
CAMK_MAPKAPK_MK2_MAPKAPK2_ST	P33241	LSP1	P49137	MAPKAPK2	S141	P147L	147	Missense	distal	6	no	13.588	13.584	EPSD	COSMIC	11.681	Down-regulation
CAMK_MAPKAPK_MK2_MAPKAPK2_ST	P33241	LSP1	P49137	MAPKAPK2	S141	P145S	145	Missense	distal	4	no	13.588	13.647	EPSD	COSMIC	11.681	Up-regulation
CAMK_MAPKAPK_MK2_MAPKAPK2_ST	P33241	LSP1	P49137	MAPKAPK2	S177	G183R	183	Missense	distal	6	no	17.187	17.215	EPSD	COSMIC	11.681	Up-regulation
CAMK_MAPKAPK_MK2_MAPKAPK2_ST	P33241	LSP1	P49137	MAPKAPK2	S177	P178S	178	Missense	proximal	1	no	17.187	17.076	EPSD	COSMIC	11.681	Down-regulation
CAMK_MAPKAPK_MK2_MAPKAPK2_ST	P33241	LSP1	P49137	MAPKAPK2	S177	P178L	178	Missense	proximal	1	no	17.187	17.278	EPSD	COSMIC;GDSC;CCLE	11.681	Up-regulation
CAMK_MAPKAPK_MK2_MAPKAPK2_ST	P33241	LSP1	P49137	MAPKAPK2	S189	G183R	183	Missense	distal	-6	no	13.928	13.856	EPSD	COSMIC	11.681	Down-regulation
CAMK_MAPKAPK_MK2_MAPKAPK2_ST	P33241	LSP1	P49137	MAPKAPK2	S189	P191S	191	Missense	proximal	2	no	13.928	14.120	EPSD	COSMIC	11.681	Up-regulation
CAMK_MAPKAPK_MK2_MAPKAPK2_ST	P33241	LSP1	P49137	MAPKAPK2	S193	P191S	191	Missense	proximal	-2	no	12.194	15.425	EPSD	COSMIC	11.681	Up-regulation
CAMK_MAPKAPK_MK2_MAPKAPK2_ST	P33241	LSP1	P49137	MAPKAPK2	S204	R201K	201	Missense	distal	-3	no	18.238	13.114	EPSD	COSMIC	11.681	Down-regulation
CAMK_MAPKAPK_MK2_MAPKAPK2_ST	P33241	LSP1	P49137	MAPKAPK2	S204	R207C	207	Missense	distal	3	no	18.238	18.188	EPSD	COSMIC	11.681	Down-regulation
CAMK_MAPKAPK_MK2_MAPKAPK2_ST	P33241	LSP1	P49137	MAPKAPK2	S204	I209T	209	Missense	distal	5	no	18.238	17.992	EPSD	COSMIC	11.681	Down-regulation
CAMK_MAPKAPK_MK2_MAPKAPK2_ST	P33241	LSP1	P49137	MAPKAPK2	S214	K217N	217	Missense	distal	3	no	13.750	13.737	EPSD	COSMIC	11.681	Down-regulation
CAMK_MAPKAPK_MK2_MAPKAPK2_ST	P33241	LSP1	P49137	MAPKAPK2	S214	R207C	207	Missense	distal	-7	no	13.750	13.829	EPSD	COSMIC	11.681	Up-regulation
CAMK_MAPKAPK_MK2_MAPKAPK2_ST	P33241	LSP1	P49137	MAPKAPK2	S214	I209T	209	Missense	distal	-5	no	13.750	13.362	EPSD	COSMIC	11.681	Down-regulation
CAMK_MAPKAPK_MK2_MAPKAPK2_ST	P33241	LSP1	P49137	MAPKAPK2	S252	R249H	249	Missense	distal	-3	no	19.119	14.360	PhosphoSitePlus	COSMIC;GDSC	11.681	Down-regulation
CAMK_MAPKAPK_MK2_MAPKAPK2_ST	P33241	LSP1	P49137	MAPKAPK2	S252	A248T	248	Missense	distal	-4	no	19.119	18.994	PhosphoSitePlus	COSMIC;GDSC;CCLE	11.681	Down-regulation
CAMK_MAPKAPK_MK2_MAPKAPK2_ST	P33241	LSP1	P49137	MAPKAPK2	S265	R266W	266	Missense	proximal	1	no	12.598	12.470	EPSD	COSMIC	11.681	Down-regulation
CAMK_MAPKAPK_MK2_MAPKAPK2_ST	P33241	LSP1	P49137	MAPKAPK2	S265	R266G	266	Missense	proximal	1	no	12.598	12.154	EPSD	COSMIC	11.681	Down-regulation
CAMK_MAPKAPK_MK2_MAPKAPK2_ST	P33241	LSP1	P49137	MAPKAPK2	S276	P281L	281	Missense	distal	5	no	13.318	13.405	EPSD	COSMIC;GDSC	11.681	Up-regulation
CAMK_MAPKAPK_MK2_MAPKAPK2_ST	P33241	LSP1	P49137	MAPKAPK2	S276	A277V	277	Missense	proximal	1	no	13.318	13.568	EPSD	COSMIC	11.681	Up-regulation
CAMK_MAPKAPK_MK2_MAPKAPK2_ST	P33241	LSP1	P49137	MAPKAPK2	S276	P281S	281	Missense	distal	5	no	13.318	13.236	EPSD	COSMIC	11.681	Down-regulation
CAMK_MAPKAPK_MK2_MAPKAPK2_ST	P33241	LSP1	P49137	MAPKAPK2	S282	A277V	277	Missense	distal	-5	no	11.344	12.015	EPSD	COSMIC	11.681	Gain
CAMK_MAPKAPK_MK2_MAPKAPK2_ST	O75925	PIAS1	P49137	MAPKAPK2	S92	P86T	86	Missense	distal	-6	no	13.120	13.104	EPSD	COSMIC	11.681	Down-regulation
CAMK_MAPKAPK_MK2_MAPKAPK2_ST	O75925	PIAS1	P49137	MAPKAPK2	S106	S106L	106	Missense	central	0	yes	12.369	0.000	EPSD	COSMIC	11.681	Loss
CAMK_MAPKAPK_MK2_MAPKAPK2_ST	O75925	PIAS1	P49137	MAPKAPK2	S106	D100Y	100	Missense	distal	-6	no	12.369	12.407	EPSD	COSMIC	11.681	Up-regulation
CAMK_MAPKAPK_MK2_MAPKAPK2_ST	O75925	PIAS1	P49137	MAPKAPK2	S106	L108S	108	Missense	proximal	2	no	12.369	12.784	EPSD	COSMIC	11.681	Up-regulation
CAMK_MAPKAPK_MK2_MAPKAPK2_ST	O75925	PIAS1	P49137	MAPKAPK2	S106	H102Y	102	Missense	distal	-4	no	12.369	12.462	EPSD	COSMIC	11.681	Up-regulation
CAMK_MAPKAPK_MK2_MAPKAPK2_ST	O75925	PIAS1	P49137	MAPKAPK2	S106	P110L	110	Missense	distal	4	no	12.369	12.276	EPSD	COSMIC;GDSC;CCLE	11.681	Down-regulation
CAMK_MAPKAPK_MK2_MAPKAPK2_ST	O75925	PIAS1	P49137	MAPKAPK2	S451	V457L	457	Missense	distal	6	no	12.877	12.880	EPSD	COSMIC	11.681	Up-regulation
CAMK_MAPKAPK_MK2_MAPKAPK2_ST	O75925	PIAS1	P49137	MAPKAPK2	S485	P482S	482	Missense	distal	-3	no	14.895	13.230	EPSD	COSMIC	11.681	Down-regulation
CAMK_MAPKAPK_MK2_MAPKAPK2_ST	O75925	PIAS1	P49137	MAPKAPK2	T487	P482S	482	Missense	distal	-5	no	11.846	11.857	EPSD	COSMIC	11.681	Up-regulation
CAMK_MAPKAPK_MK2_MAPKAPK2_ST	O75925	PIAS1	P49137	MAPKAPK2	T635	T630I	630	Missense	distal	-5	no	14.759	15.146	EPSD	COSMIC	11.681	Up-regulation
CAMK_MAPKAPK_MK2_MAPKAPK2_ST	O75925	PIAS1	P49137	MAPKAPK2	T635	T628I	628	Missense	distal	-7	no	14.759	14.821	EPSD	COSMIC	11.681	Up-regulation
CAMK_MAPKAPK_MK2_MAPKAPK2_ST	Q00613	HSF1	P49137	MAPKAPK2	S136	D129G	129	Missense	distal	-7	no	17.499	17.517	EPSD	COSMIC	11.681	Up-regulation
CAMK_MAPKAPK_MK2_MAPKAPK2_ST	Q00613	HSF1	P49137	MAPKAPK2	S136	R133S	133	Missense	distal	-3	no	17.499	11.170	EPSD	COSMIC	11.681	Loss
CAMK_MAPKAPK_MK2_MAPKAPK2_ST	Q00613	HSF1	P49137	MAPKAPK2	S136	V137I	137	Missense	proximal	1	no	17.499	17.408	EPSD	COSMIC	11.681	Down-regulation
CAMK_MAPKAPK_MK2_MAPKAPK2_ST	Q00613	HSF1	P49137	MAPKAPK2	S136	K139N	139	Missense	distal	3	no	17.499	17.486	EPSD	COSMIC;GDSC;CCLE	11.681	Down-regulation
CAMK_MAPKAPK_MK2_MAPKAPK2_ST	Q00613	HSF1	P49137	MAPKAPK2	S218	L211P	211	Missense	distal	-7	no	12.045	12.010	EPSD	COSMIC	11.681	Down-regulation
CAMK_MAPKAPK_MK2_MAPKAPK2_ST	Q00613	HSF1	P49137	MAPKAPK2	S218	L211R	211	Missense	distal	-7	no	12.045	11.978	EPSD	COSMIC	11.681	Down-regulation
CAMK_MAPKAPK_MK2_MAPKAPK2_ST	Q00613	HSF1	P49137	MAPKAPK2	S230	R227Q	227	Missense	distal	-3	no	18.051	12.287	EPSD	COSMIC;GDSC	11.681	Down-regulation
CAMK_MAPKAPK_MK2_MAPKAPK2_ST	Q00613	HSF1	P49137	MAPKAPK2	S230	G236S	236	Missense	distal	6	no	18.051	18.082	EPSD	COSMIC;CCLE	11.681	Up-regulation
CAMK_MAPKAPK_MK2_MAPKAPK2_ST	Q00613	HSF1	P49137	MAPKAPK2	S230	S237L	237	Missense	distal	7	no	18.051	17.694	EPSD	COSMIC	11.681	Down-regulation
CAMK_MAPKAPK_MK2_MAPKAPK2_ST	Q00613	HSF1	P49137	MAPKAPK2	S248	S244F	244	Missense	distal	-4	no	12.237	12.632	EPSD	COSMIC	11.681	Up-regulation
CAMK_MAPKAPK_MK2_MAPKAPK2_ST	Q00613	HSF1	P49137	MAPKAPK2	S250	S244F	244	Missense	distal	-6	no	13.284	13.393	EPSD	COSMIC	11.681	Up-regulation
CAMK_MAPKAPK_MK2_MAPKAPK2_ST	Q00613	HSF1	P49137	MAPKAPK2	S251	S244F	244	Missense	distal	-7	no	13.186	13.275	EPSD	COSMIC	11.681	Up-regulation
CAMK_MAPKAPK_MK2_MAPKAPK2_ST	Q00613	HSF1	P49137	MAPKAPK2	S279	S279F	279	Missense	central	0	yes	11.909	0.000	EPSD	COSMIC	11.681	Loss
CAMK_MAPKAPK_MK2_MAPKAPK2_ST	Q00613	HSF1	P49137	MAPKAPK2	S279	P280L	280	Missense	proximal	1	no	11.909	12.000	EPSD	COSMIC	11.681	Up-regulation
CAMK_MAPKAPK_MK2_MAPKAPK2_ST	Q00613	HSF1	P49137	MAPKAPK2	S279	G281S	281	Missense	proximal	2	no	11.909	12.343	EPSD	COSMIC	11.681	Up-regulation
CAMK_MAPKAPK_MK2_MAPKAPK2_ST	Q00613	HSF1	P49137	MAPKAPK2	S279	S283N	283	Missense	distal	4	no	11.909	11.715	EPSD	COSMIC	11.681	Down-regulation
CAMK_MAPKAPK_MK2_MAPKAPK2_ST	Q00613	HSF1	P49137	MAPKAPK2	S283	S279F	279	Missense	distal	-4	no	11.368	11.763	EPSD	COSMIC	11.681	Gain
CAMK_MAPKAPK_MK2_MAPKAPK2_ST	Q00613	HSF1	P49137	MAPKAPK2	S283	G281S	281	Missense	proximal	-2	no	11.368	14.706	EPSD	COSMIC	11.681	Gain
CAMK_MAPKAPK_MK2_MAPKAPK2_ST	Q00613	HSF1	P49137	MAPKAPK2	S290	R287K	287	Missense	distal	-3	no	15.437	10.313	EPSD	COSMIC	11.681	Loss
CAMK_MAPKAPK_MK2_MAPKAPK2_ST	Q00613	HSF1	P49137	MAPKAPK2	S290	S283N	283	Missense	distal	-7	no	15.437	15.487	EPSD	COSMIC	11.681	Up-regulation
CAMK_MAPKAPK_MK2_MAPKAPK2_ST	Q00613	HSF1	P49137	MAPKAPK2	S292	R287K	287	Missense	distal	-5	no	15.145	14.333	EPSD	COSMIC	11.681	Down-regulation
CAMK_MAPKAPK_MK2_MAPKAPK2_ST	Q00613	HSF1	P49137	MAPKAPK2	S303	P304L	304	Missense	proximal	1	no	11.597	11.688	EPSD	COSMIC;GDSC	11.681	Gain
CAMK_MAPKAPK_MK2_MAPKAPK2_ST	Q00613	HSF1	P49137	MAPKAPK2	S307	S303G	303	Missense	distal	-4	no	12.426	12.763	EPSD	COSMIC	11.681	Up-regulation
CAMK_MAPKAPK_MK2_MAPKAPK2_ST	Q00613	HSF1	P49137	MAPKAPK2	S307	P304L	304	Missense	distal	-3	no	12.426	12.000	EPSD	COSMIC;GDSC	11.681	Down-regulation
CAMK_MAPKAPK_MK2_MAPKAPK2_ST	Q00613	HSF1	P49137	MAPKAPK2	S307	R309G	309	Missense	proximal	2	no	12.426	12.096	EPSD	COSMIC	11.681	Down-regulation
CAMK_MAPKAPK_MK2_MAPKAPK2_ST	Q00613	HSF1	P49137	MAPKAPK2	S320	P318T	318	Missense	proximal	-2	no	17.071	18.548	EPSD	COSMIC	11.681	Up-regulation
CAMK_MAPKAPK_MK2_MAPKAPK2_ST	Q00613	HSF1	P49137	MAPKAPK2	S320	P327Q	327	Missense	distal	7	no	17.071	16.619	EPSD	COSMIC	11.681	Down-regulation
CAMK_MAPKAPK_MK2_MAPKAPK2_ST	Q00613	HSF1	P49137	MAPKAPK2	S326	L330V	330	Missense	distal	4	no	12.640	12.664	EPSD	COSMIC	11.681	Up-regulation
CAMK_MAPKAPK_MK2_MAPKAPK2_ST	Q00613	HSF1	P49137	MAPKAPK2	S326	P327Q	327	Missense	proximal	1	no	12.640	12.100	EPSD	COSMIC	11.681	Down-regulation
CAMK_MAPKAPK_MK2_MAPKAPK2_ST	Q00613	HSF1	P49137	MAPKAPK2	S338	P342T	342	Missense	distal	4	no	12.439	12.546	EPSD	COSMIC	11.681	Up-regulation
CAMK_MAPKAPK_MK2_MAPKAPK2_ST	Q00613	HSF1	P49137	MAPKAPK2	S338	S344C	344	Missense	distal	6	no	12.439	12.411	EPSD	COSMIC	11.681	Down-regulation
CAMK_MAPKAPK_MK2_MAPKAPK2_ST	Q00613	HSF1	P49137	MAPKAPK2	S338	R336W	336	Missense	proximal	-2	no	12.439	10.689	EPSD	COSMIC	11.681	Loss
CAMK_MAPKAPK_MK2_MAPKAPK2_ST	Q00613	HSF1	P49137	MAPKAPK2	T355	D356N	356	Missense	proximal	1	no	13.826	13.695	EPSD	COSMIC	11.681	Down-regulation
CAMK_MAPKAPK_MK2_MAPKAPK2_ST	Q00613	HSF1	P49137	MAPKAPK2	T355	T349M	349	Missense	distal	-6	no	13.826	13.883	EPSD	COSMIC	11.681	Up-regulation
CAMK_MAPKAPK_MK2_MAPKAPK2_ST	Q00613	HSF1	P49137	MAPKAPK2	T355	H354Y	354	Missense	proximal	-1	no	13.826	13.832	EPSD	COSMIC	11.681	Up-regulation
CAMK_MAPKAPK_MK2_MAPKAPK2_ST	Q00613	HSF1	P49137	MAPKAPK2	T355	E358K	358	Missense	distal	3	no	13.826	13.699	EPSD	COSMIC	11.681	Down-regulation
CAMK_MAPKAPK_MK2_MAPKAPK2_ST	Q00613	HSF1	P49137	MAPKAPK2	S363	S363P	363	Missense	central	0	yes	18.111	0.000	EPSD	COSMIC	11.681	Loss
CAMK_MAPKAPK_MK2_MAPKAPK2_ST	Q00613	HSF1	P49137	MAPKAPK2	S363	P365Q	365	Missense	proximal	2	no	18.111	17.894	EPSD	COSMIC	11.681	Down-regulation
CAMK_MAPKAPK_MK2_MAPKAPK2_ST	Q00613	HSF1	P49137	MAPKAPK2	S363	D356N	356	Missense	distal	-7	no	18.111	18.121	EPSD	COSMIC	11.681	Up-regulation
CAMK_MAPKAPK_MK2_MAPKAPK2_ST	Q00613	HSF1	P49137	MAPKAPK2	S363	P365T	365	Missense	proximal	2	no	18.111	18.326	EPSD	COSMIC	11.681	Up-regulation
CAMK_MAPKAPK_MK2_MAPKAPK2_ST	Q00613	HSF1	P49137	MAPKAPK2	S363	E358K	358	Missense	distal	-5	no	18.111	17.503	EPSD	COSMIC	11.681	Down-regulation
CAMK_MAPKAPK_MK2_MAPKAPK2_ST	Q00613	HSF1	P49137	MAPKAPK2	S363	P365L	365	Missense	proximal	2	no	18.111	17.888	EPSD	COSMIC	11.681	Down-regulation
CAMK_MAPKAPK_MK2_MAPKAPK2_ST	Q00613	HSF1	P49137	MAPKAPK2	S458	P452H	452	Missense	distal	-6	no	12.274	12.351	EPSD	COSMIC	11.681	Up-regulation
CAMK_MAPKAPK_MK2_MAPKAPK2_ST	Q00613	HSF1	P49137	MAPKAPK2	S513	E519K	519	Missense	distal	6	no	12.325	12.310	EPSD	COSMIC	11.681	Down-regulation
CAMK_MAPKAPK_MK2_MAPKAPK2_ST	Q00613	HSF1	P49137	MAPKAPK2	S518	E519K	519	Missense	proximal	1	no	12.535	12.071	EPSD	COSMIC	11.681	Down-regulation
CAMK_MAPKAPK_MK2_MAPKAPK2_ST	Q07817	BCL2L1	P49137	MAPKAPK2	S62	A64T	64	Missense	proximal	2	no	12.896	12.949	PhosphoSitePlus	COSMIC;GDSC;CCLE	11.681	Up-regulation
CAMK_MAPKAPK_MK2_MAPKAPK2_ST	Q07817	BCL2L1	P49137	MAPKAPK2	S62	A60V	60	Missense	proximal	-2	no	12.896	10.696	PhosphoSitePlus	COSMIC;GDSC;CCLE	11.681	Loss
CAMK_MAPKAPK_MK2_MAPKAPK2_ST	Q16875	PFKFB3	P49137	MAPKAPK2	S22	G28E	28	Missense	distal	6	no	12.182	12.197	EPSD	COSMIC	11.681	Up-regulation
CAMK_MAPKAPK_MK2_MAPKAPK2_ST	Q16875	PFKFB3	P49137	MAPKAPK2	S22	C27R	27	Missense	distal	5	no	12.182	11.957	EPSD	COSMIC;CCLE	11.681	Down-regulation
CAMK_MAPKAPK_MK2_MAPKAPK2_ST	Q16875	PFKFB3	P49137	MAPKAPK2	S22	V15A	15	Missense	distal	-7	no	12.182	12.138	EPSD	COSMIC	11.681	Down-regulation
CAMK_MAPKAPK_MK2_MAPKAPK2_ST	Q16875	PFKFB3	P49137	MAPKAPK2	S211	S211L	211	Missense	central	0	yes	14.175	0.000	EPSD	COSMIC	11.681	Loss
CAMK_MAPKAPK_MK2_MAPKAPK2_ST	Q16875	PFKFB3	P49137	MAPKAPK2	S211	S211P	211	Missense	central	0	yes	14.175	0.000	EPSD	COSMIC	11.681	Loss
CAMK_MAPKAPK_MK2_MAPKAPK2_ST	Q16875	PFKFB3	P49137	MAPKAPK2	S211	S211R	211	Missense	central	0	yes	14.175	0.000	EPSD	COSMIC	11.681	Loss
CAMK_MAPKAPK_MK2_MAPKAPK2_ST	Q16875	PFKFB3	P49137	MAPKAPK2	S211	S211N	211	Missense	central	0	yes	14.175	0.000	EPSD	COSMIC	11.681	Loss
CAMK_MAPKAPK_MK2_MAPKAPK2_ST	Q16875	PFKFB3	P49137	MAPKAPK2	S446	R443Q	443	Missense	distal	-3	no	16.027	10.263	EPSD	COSMIC	11.681	Loss
CAMK_MAPKAPK_MK2_MAPKAPK2_ST	Q16875	PFKFB3	P49137	MAPKAPK2	S446	K451R	451	Missense	distal	5	no	16.027	15.740	EPSD	COSMIC	11.681	Down-regulation
CAMK_MAPKAPK_MK2_MAPKAPK2_ST	Q16875	PFKFB3	P49137	MAPKAPK2	S446	K450E	450	Missense	distal	4	no	16.027	16.208	EPSD	COSMIC	11.681	Up-regulation
CAMK_MAPKAPK_MK2_MAPKAPK2_ST	Q16875	PFKFB3	P49137	MAPKAPK2	S461	S467N	467	Missense	distal	6	no	18.167	18.143	PhosphoSitePlus	COSMIC;GDSC;CCLE	11.681	Down-regulation
CAMK_MAPKAPK_MK2_MAPKAPK2_ST	Q16875	PFKFB3	P49137	MAPKAPK2	S461	S467L	467	Missense	distal	6	no	18.167	18.147	PhosphoSitePlus	COSMIC	11.681	Down-regulation
CAMK_MAPKAPK_MK2_MAPKAPK2_ST	Q16875	PFKFB3	P49137	MAPKAPK2	S478	E481K	481	Missense	distal	3	no	15.214	15.087	EPSD	COSMIC	11.681	Down-regulation
CAMK_MAPKAPK_MK2_MAPKAPK2_ST	P49815	TSC2	P49137	MAPKAPK2	S311	G305E	305	Missense	distal	-6	no	14.604	14.525	EPSD	COSMIC	11.681	Down-regulation
CAMK_MAPKAPK_MK2_MAPKAPK2_ST	P49815	TSC2	P49137	MAPKAPK2	S311	A306T	306	Missense	distal	-5	no	14.604	15.006	EPSD	COSMIC	11.681	Up-regulation
CAMK_MAPKAPK_MK2_MAPKAPK2_ST	P49815	TSC2	P49137	MAPKAPK2	S311	Y310C	310	Missense	proximal	-1	no	14.604	14.596	EPSD	COSMIC	11.681	Down-regulation
CAMK_MAPKAPK_MK2_MAPKAPK2_ST	P49815	TSC2	P49137	MAPKAPK2	S311	P316L	316	Missense	distal	5	no	14.604	14.690	EPSD	COSMIC	11.681	Up-regulation
CAMK_MAPKAPK_MK2_MAPKAPK2_ST	P49815	TSC2	P49137	MAPKAPK2	S311	S311Y	311	Missense	central	0	yes	14.604	0.000	EPSD	COSMIC	11.681	Loss
CAMK_MAPKAPK_MK2_MAPKAPK2_ST	P49815	TSC2	P49137	MAPKAPK2	S311	G305V	305	Missense	distal	-6	no	14.604	14.564	EPSD	COSMIC	11.681	Down-regulation
CAMK_MAPKAPK_MK2_MAPKAPK2_ST	P49815	TSC2	P49137	MAPKAPK2	S311	A306S	306	Missense	distal	-5	no	14.604	15.088	EPSD	COSMIC	11.681	Up-regulation
CAMK_MAPKAPK_MK2_MAPKAPK2_ST	P49815	TSC2	P49137	MAPKAPK2	S540	S540F	540	Missense	central	0	yes	19.462	0.000	EPSD	COSMIC	11.681	Loss
CAMK_MAPKAPK_MK2_MAPKAPK2_ST	P49815	TSC2	P49137	MAPKAPK2	S540	P542L	542	Missense	proximal	2	no	19.462	19.239	EPSD	COSMIC	11.681	Down-regulation
CAMK_MAPKAPK_MK2_MAPKAPK2_ST	P49815	TSC2	P49137	MAPKAPK2	S540	S538P	538	Missense	proximal	-2	no	19.462	16.230	EPSD	COSMIC	11.681	Down-regulation
CAMK_MAPKAPK_MK2_MAPKAPK2_ST	P49815	TSC2	P49137	MAPKAPK2	S540	L539F	539	Missense	proximal	-1	no	19.462	19.478	EPSD	COSMIC	11.681	Up-regulation
CAMK_MAPKAPK_MK2_MAPKAPK2_ST	P49815	TSC2	P49137	MAPKAPK2	S540	P543Q	543	Missense	distal	3	no	19.462	19.303	EPSD	COSMIC	11.681	Down-regulation
CAMK_MAPKAPK_MK2_MAPKAPK2_ST	P49815	TSC2	P49137	MAPKAPK2	S609	R611Q	611	Missense	proximal	2	no	12.074	11.770	EPSD	COSMIC	11.681	Down-regulation
CAMK_MAPKAPK_MK2_MAPKAPK2_ST	P49815	TSC2	P49137	MAPKAPK2	S609	R611W	611	Missense	proximal	2	no	12.074	11.764	EPSD	COSMIC	11.681	Down-regulation
CAMK_MAPKAPK_MK2_MAPKAPK2_ST	P49815	TSC2	P49137	MAPKAPK2	S609	A614S	614	Missense	distal	5	no	12.074	12.035	EPSD	COSMIC	11.681	Down-regulation
CAMK_MAPKAPK_MK2_MAPKAPK2_ST	P49815	TSC2	P49137	MAPKAPK2	S609	T603I	603	Missense	distal	-6	no	12.074	12.128	EPSD	COSMIC	11.681	Up-regulation
CAMK_MAPKAPK_MK2_MAPKAPK2_ST	P49815	TSC2	P49137	MAPKAPK2	S609	R611P	611	Missense	proximal	2	no	12.074	11.987	EPSD	COSMIC	11.681	Down-regulation
CAMK_MAPKAPK_MK2_MAPKAPK2_ST	P49815	TSC2	P49137	MAPKAPK2	S609	I606F	606	Missense	distal	-3	no	12.074	6.159	EPSD	COSMIC	11.681	Loss
CAMK_MAPKAPK_MK2_MAPKAPK2_ST	P49815	TSC2	P49137	MAPKAPK2	S609	D616N	616	Missense	distal	7	no	12.074	11.896	EPSD	COSMIC	11.681	Down-regulation
CAMK_MAPKAPK_MK2_MAPKAPK2_ST	P49815	TSC2	P49137	MAPKAPK2	S937	E942K	942	Missense	distal	5	no	18.542	18.755	EPSD	COSMIC	11.681	Up-regulation
CAMK_MAPKAPK_MK2_MAPKAPK2_ST	P49815	TSC2	P49137	MAPKAPK2	S937	R936Q	936	Missense	proximal	-1	no	18.542	18.566	EPSD	COSMIC	11.681	Up-regulation
CAMK_MAPKAPK_MK2_MAPKAPK2_ST	P49815	TSC2	P49137	MAPKAPK2	S937	A935S	935	Missense	proximal	-2	no	18.542	20.137	EPSD	COSMIC	11.681	Up-regulation
CAMK_MAPKAPK_MK2_MAPKAPK2_ST	P49815	TSC2	P49137	MAPKAPK2	S937	S932N	932	Missense	distal	-5	no	18.542	17.845	EPSD	COSMIC	11.681	Down-regulation
CAMK_MAPKAPK_MK2_MAPKAPK2_ST	P49815	TSC2	P49137	MAPKAPK2	S937	T938I	938	Missense	proximal	1	no	18.542	18.495	EPSD	COSMIC	11.681	Down-regulation
CAMK_MAPKAPK_MK2_MAPKAPK2_ST	P49815	TSC2	P49137	MAPKAPK2	S939	E942K	942	Missense	distal	3	no	19.644	19.517	EPSD	COSMIC	11.681	Down-regulation
CAMK_MAPKAPK_MK2_MAPKAPK2_ST	P49815	TSC2	P49137	MAPKAPK2	S939	R936Q	936	Missense	distal	-3	no	19.644	13.880	EPSD	COSMIC	11.681	Down-regulation
CAMK_MAPKAPK_MK2_MAPKAPK2_ST	P49815	TSC2	P49137	MAPKAPK2	S939	K945E	945	Missense	distal	6	no	19.644	19.659	EPSD	COSMIC	11.681	Up-regulation
CAMK_MAPKAPK_MK2_MAPKAPK2_ST	P49815	TSC2	P49137	MAPKAPK2	S939	A935S	935	Missense	distal	-4	no	19.644	19.508	EPSD	COSMIC	11.681	Down-regulation
CAMK_MAPKAPK_MK2_MAPKAPK2_ST	P49815	TSC2	P49137	MAPKAPK2	S939	S932N	932	Missense	distal	-7	no	19.644	19.694	EPSD	COSMIC	11.681	Up-regulation
CAMK_MAPKAPK_MK2_MAPKAPK2_ST	P49815	TSC2	P49137	MAPKAPK2	S939	S946I	946	Missense	distal	7	no	19.644	19.381	EPSD	COSMIC	11.681	Down-regulation
CAMK_MAPKAPK_MK2_MAPKAPK2_ST	P49815	TSC2	P49137	MAPKAPK2	S939	T938I	938	Missense	proximal	-1	no	19.644	19.650	EPSD	COSMIC	11.681	Up-regulation
CAMK_MAPKAPK_MK2_MAPKAPK2_ST	P49815	TSC2	P49137	MAPKAPK2	S946	E942K	942	Missense	distal	-4	no	16.852	17.019	EPSD	COSMIC	11.681	Up-regulation
CAMK_MAPKAPK_MK2_MAPKAPK2_ST	P49815	TSC2	P49137	MAPKAPK2	S946	K945E	945	Missense	proximal	-1	no	16.852	16.842	EPSD	COSMIC	11.681	Down-regulation
CAMK_MAPKAPK_MK2_MAPKAPK2_ST	P49815	TSC2	P49137	MAPKAPK2	S946	S946I	946	Missense	central	0	yes	16.852	0.000	EPSD	COSMIC	11.681	Loss
CAMK_MAPKAPK_MK2_MAPKAPK2_ST	P49815	TSC2	P49137	MAPKAPK2	S960	N958S	958	Missense	proximal	-2	no	10.788	13.152	EPSD	COSMIC	11.681	Gain
CAMK_MAPKAPK_MK2_MAPKAPK2_ST	P49815	TSC2	P49137	MAPKAPK2	S979	S979R	979	Missense	central	0	yes	16.711	0.000	EPSD	COSMIC	11.681	Loss
CAMK_MAPKAPK_MK2_MAPKAPK2_ST	P49815	TSC2	P49137	MAPKAPK2	S979	E984V	984	Missense	distal	5	no	16.711	16.802	EPSD	COSMIC	11.681	Up-regulation
CAMK_MAPKAPK_MK2_MAPKAPK2_ST	P49815	TSC2	P49137	MAPKAPK2	S979	R976W	976	Missense	distal	-3	no	16.711	8.132	EPSD	COSMIC	11.681	Loss
CAMK_MAPKAPK_MK2_MAPKAPK2_ST	P49815	TSC2	P49137	MAPKAPK2	S979	S981R	981	Missense	proximal	2	no	16.711	16.607	EPSD	COSMIC	11.681	Down-regulation
CAMK_MAPKAPK_MK2_MAPKAPK2_ST	P49815	TSC2	P49137	MAPKAPK2	S979	V982I	982	Missense	distal	3	no	16.711	16.661	EPSD	COSMIC	11.681	Down-regulation
CAMK_MAPKAPK_MK2_MAPKAPK2_ST	P49815	TSC2	P49137	MAPKAPK2	S981	R988Q	988	Missense	distal	7	no	21.035	20.673	EPSD	COSMIC	11.681	Down-regulation
CAMK_MAPKAPK_MK2_MAPKAPK2_ST	P49815	TSC2	P49137	MAPKAPK2	S981	S979R	979	Missense	proximal	-2	no	21.035	18.769	EPSD	COSMIC	11.681	Down-regulation
CAMK_MAPKAPK_MK2_MAPKAPK2_ST	P49815	TSC2	P49137	MAPKAPK2	S981	E984V	984	Missense	distal	3	no	21.035	20.992	EPSD	COSMIC	11.681	Down-regulation
CAMK_MAPKAPK_MK2_MAPKAPK2_ST	P49815	TSC2	P49137	MAPKAPK2	S981	R976W	976	Missense	distal	-5	no	21.035	20.681	EPSD	COSMIC	11.681	Down-regulation
CAMK_MAPKAPK_MK2_MAPKAPK2_ST	P49815	TSC2	P49137	MAPKAPK2	S981	S981R	981	Missense	central	0	yes	21.035	0.000	EPSD	COSMIC	11.681	Loss
CAMK_MAPKAPK_MK2_MAPKAPK2_ST	P49815	TSC2	P49137	MAPKAPK2	S981	V982I	982	Missense	proximal	1	no	21.035	20.944	EPSD	COSMIC	11.681	Down-regulation
CAMK_MAPKAPK_MK2_MAPKAPK2_ST	P49815	TSC2	P49137	MAPKAPK2	S981	V987A	987	Missense	distal	6	no	21.035	21.049	EPSD	COSMIC	11.681	Up-regulation
CAMK_MAPKAPK_MK2_MAPKAPK2_ST	P49815	TSC2	P49137	MAPKAPK2	S983	R988Q	988	Missense	distal	5	no	12.332	12.551	EPSD	COSMIC	11.681	Up-regulation
CAMK_MAPKAPK_MK2_MAPKAPK2_ST	P49815	TSC2	P49137	MAPKAPK2	S983	S979R	979	Missense	distal	-4	no	12.332	12.344	EPSD	COSMIC	11.681	Up-regulation
CAMK_MAPKAPK_MK2_MAPKAPK2_ST	P49815	TSC2	P49137	MAPKAPK2	S983	E984V	984	Missense	proximal	1	no	12.332	12.439	EPSD	COSMIC	11.681	Up-regulation
CAMK_MAPKAPK_MK2_MAPKAPK2_ST	P49815	TSC2	P49137	MAPKAPK2	S983	R976W	976	Missense	distal	-7	no	12.332	12.411	EPSD	COSMIC	11.681	Up-regulation
CAMK_MAPKAPK_MK2_MAPKAPK2_ST	P49815	TSC2	P49137	MAPKAPK2	S983	S981R	981	Missense	proximal	-2	no	12.332	10.065	EPSD	COSMIC	11.681	Loss
CAMK_MAPKAPK_MK2_MAPKAPK2_ST	P49815	TSC2	P49137	MAPKAPK2	S983	V987A	987	Missense	distal	4	no	12.332	12.483	EPSD	COSMIC	11.681	Up-regulation
CAMK_MAPKAPK_MK2_MAPKAPK2_ST	P49815	TSC2	P49137	MAPKAPK2	S999	S1002L	1002	Missense	distal	3	no	13.470	13.354	EPSD	COSMIC	11.681	Down-regulation
CAMK_MAPKAPK_MK2_MAPKAPK2_ST	P49815	TSC2	P49137	MAPKAPK2	S999	T993M	993	Missense	distal	-6	no	13.470	13.526	EPSD	COSMIC	11.681	Up-regulation
CAMK_MAPKAPK_MK2_MAPKAPK2_ST	P49815	TSC2	P49137	MAPKAPK2	S999	S999L	999	Missense	central	0	yes	13.470	0.000	EPSD	COSMIC	11.681	Loss
CAMK_MAPKAPK_MK2_MAPKAPK2_ST	P49815	TSC2	P49137	MAPKAPK2	S999	S999P	999	Missense	central	0	yes	13.470	0.000	EPSD	COSMIC	11.681	Loss
CAMK_MAPKAPK_MK2_MAPKAPK2_ST	P49815	TSC2	P49137	MAPKAPK2	S1096	S1094L	1094	Missense	proximal	-2	no	13.090	9.732	EPSD	COSMIC	11.681	Loss
CAMK_MAPKAPK_MK2_MAPKAPK2_ST	P49815	TSC2	P49137	MAPKAPK2	S1096	G1099W	1099	Missense	distal	3	no	13.090	13.082	EPSD	COSMIC	11.681	Down-regulation
CAMK_MAPKAPK_MK2_MAPKAPK2_ST	P49815	TSC2	P49137	MAPKAPK2	S1096	E1093K	1093	Missense	distal	-3	no	13.090	13.261	EPSD	COSMIC	11.681	Up-regulation
CAMK_MAPKAPK_MK2_MAPKAPK2_ST	P49815	TSC2	P49137	MAPKAPK2	S1096	S1095I	1095	Missense	proximal	-1	no	13.090	13.092	EPSD	COSMIC	11.681	Up-regulation
CAMK_MAPKAPK_MK2_MAPKAPK2_ST	P49815	TSC2	P49137	MAPKAPK2	S1096	S1097C	1097	Missense	proximal	1	no	13.090	12.851	EPSD	COSMIC	11.681	Down-regulation
CAMK_MAPKAPK_MK2_MAPKAPK2_ST	P49815	TSC2	P49137	MAPKAPK2	S1121	V1128I	1128	Missense	distal	7	no	11.737	11.698	EPSD	COSMIC	11.681	Down-regulation
CAMK_MAPKAPK_MK2_MAPKAPK2_ST	P49815	TSC2	P49137	MAPKAPK2	S1121	G1117R	1117	Missense	distal	-4	no	11.737	11.412	EPSD	COSMIC	11.681	Loss
CAMK_MAPKAPK_MK2_MAPKAPK2_ST	P49815	TSC2	P49137	MAPKAPK2	S1121	A1124V	1124	Missense	distal	3	no	11.737	11.633	EPSD	COSMIC;CCLE	11.681	Loss
CAMK_MAPKAPK_MK2_MAPKAPK2_ST	P49815	TSC2	P49137	MAPKAPK2	S1121	R1125Q	1125	Missense	distal	4	no	11.737	11.602	EPSD	COSMIC	11.681	Loss
CAMK_MAPKAPK_MK2_MAPKAPK2_ST	P49815	TSC2	P49137	MAPKAPK2	S1121	R1127W	1127	Missense	distal	6	no	11.737	11.712	EPSD	COSMIC	11.681	Down-regulation
CAMK_MAPKAPK_MK2_MAPKAPK2_ST	P49815	TSC2	P49137	MAPKAPK2	S1121	R1122C	1122	Missense	proximal	1	no	11.737	11.476	EPSD	COSMIC;CCLE	11.681	Loss
CAMK_MAPKAPK_MK2_MAPKAPK2_ST	P49815	TSC2	P49137	MAPKAPK2	S1121	A1116V	1116	Missense	distal	-5	no	11.737	12.409	EPSD	COSMIC	11.681	Up-regulation
CAMK_MAPKAPK_MK2_MAPKAPK2_ST	P49815	TSC2	P49137	MAPKAPK2	S1130	V1128I	1128	Missense	proximal	-2	no	16.204	15.658	EPSD	COSMIC	11.681	Down-regulation
CAMK_MAPKAPK_MK2_MAPKAPK2_ST	P49815	TSC2	P49137	MAPKAPK2	S1130	M1131L	1131	Missense	proximal	1	no	16.204	16.575	EPSD	COSMIC	11.681	Up-regulation
CAMK_MAPKAPK_MK2_MAPKAPK2_ST	P49815	TSC2	P49137	MAPKAPK2	S1130	A1124V	1124	Missense	distal	-6	no	16.204	16.233	EPSD	COSMIC;CCLE	11.681	Up-regulation
CAMK_MAPKAPK_MK2_MAPKAPK2_ST	P49815	TSC2	P49137	MAPKAPK2	S1130	R1125Q	1125	Missense	distal	-5	no	16.204	15.486	EPSD	COSMIC	11.681	Down-regulation
CAMK_MAPKAPK_MK2_MAPKAPK2_ST	P49815	TSC2	P49137	MAPKAPK2	S1130	R1127W	1127	Missense	distal	-3	no	16.204	7.625	EPSD	COSMIC	11.681	Loss
CAMK_MAPKAPK_MK2_MAPKAPK2_ST	P49815	TSC2	P49137	MAPKAPK2	S1130	S1132L	1132	Missense	proximal	2	no	16.204	15.789	EPSD	COSMIC	11.681	Down-regulation
CAMK_MAPKAPK_MK2_MAPKAPK2_ST	P49815	TSC2	P49137	MAPKAPK2	S1130	R1129C	1129	Missense	proximal	-1	no	16.204	16.225	EPSD	COSMIC	11.681	Up-regulation
CAMK_MAPKAPK_MK2_MAPKAPK2_ST	P49815	TSC2	P49137	MAPKAPK2	S1130	S1130C	1130	Missense	central	0	yes	16.204	0.000	EPSD	COSMIC	11.681	Loss
CAMK_MAPKAPK_MK2_MAPKAPK2_ST	P49815	TSC2	P49137	MAPKAPK2	S1130	H1135R	1135	Missense	distal	5	no	16.204	15.898	EPSD	COSMIC	11.681	Down-regulation
CAMK_MAPKAPK_MK2_MAPKAPK2_ST	P49815	TSC2	P49137	MAPKAPK2	S1130	G1134S	1134	Missense	distal	4	no	16.204	16.393	EPSD	COSMIC	11.681	Up-regulation
CAMK_MAPKAPK_MK2_MAPKAPK2_ST	P49815	TSC2	P49137	MAPKAPK2	S1132	V1128I	1128	Missense	distal	-4	no	18.682	18.610	EPSD	COSMIC	11.681	Down-regulation
CAMK_MAPKAPK_MK2_MAPKAPK2_ST	P49815	TSC2	P49137	MAPKAPK2	S1132	M1131L	1131	Missense	proximal	-1	no	18.682	18.674	EPSD	COSMIC	11.681	Down-regulation
CAMK_MAPKAPK_MK2_MAPKAPK2_ST	P49815	TSC2	P49137	MAPKAPK2	S1132	R1125Q	1125	Missense	distal	-7	no	18.682	18.768	EPSD	COSMIC	11.681	Up-regulation
CAMK_MAPKAPK_MK2_MAPKAPK2_ST	P49815	TSC2	P49137	MAPKAPK2	S1132	R1127W	1127	Missense	distal	-5	no	18.682	18.327	EPSD	COSMIC	11.681	Down-regulation
CAMK_MAPKAPK_MK2_MAPKAPK2_ST	P49815	TSC2	P49137	MAPKAPK2	S1132	S1132L	1132	Missense	central	0	yes	18.682	0.000	EPSD	COSMIC	11.681	Loss
CAMK_MAPKAPK_MK2_MAPKAPK2_ST	P49815	TSC2	P49137	MAPKAPK2	S1132	R1129C	1129	Missense	distal	-3	no	18.682	10.282	EPSD	COSMIC	11.681	Loss
CAMK_MAPKAPK_MK2_MAPKAPK2_ST	P49815	TSC2	P49137	MAPKAPK2	S1132	S1130C	1130	Missense	proximal	-2	no	18.682	15.204	EPSD	COSMIC	11.681	Down-regulation
CAMK_MAPKAPK_MK2_MAPKAPK2_ST	P49815	TSC2	P49137	MAPKAPK2	S1132	H1135R	1135	Missense	distal	3	no	18.682	18.819	EPSD	COSMIC	11.681	Up-regulation
CAMK_MAPKAPK_MK2_MAPKAPK2_ST	P49815	TSC2	P49137	MAPKAPK2	S1132	G1134S	1134	Missense	proximal	2	no	18.682	19.116	EPSD	COSMIC	11.681	Up-regulation
CAMK_MAPKAPK_MK2_MAPKAPK2_ST	P49815	TSC2	P49137	MAPKAPK2	S1155	Q1148K	1148	Missense	distal	-7	no	14.029	14.017	EPSD	COSMIC	11.681	Down-regulation
CAMK_MAPKAPK_MK2_MAPKAPK2_ST	P49815	TSC2	P49137	MAPKAPK2	S1155	R1159Q	1159	Missense	distal	4	no	14.029	13.893	EPSD	COSMIC;GDSC;CCLE	11.681	Down-regulation
CAMK_MAPKAPK_MK2_MAPKAPK2_ST	P49815	TSC2	P49137	MAPKAPK2	S1155	G1151C	1151	Missense	distal	-4	no	14.029	13.931	EPSD	COSMIC	11.681	Down-regulation
CAMK_MAPKAPK_MK2_MAPKAPK2_ST	P49815	TSC2	P49137	MAPKAPK2	S1155	S1155F	1155	Missense	central	0	yes	14.029	0.000	EPSD	COSMIC	11.681	Loss
CAMK_MAPKAPK_MK2_MAPKAPK2_ST	P49815	TSC2	P49137	MAPKAPK2	S1155	S1152P	1152	Missense	distal	-3	no	14.029	15.693	EPSD	COSMIC	11.681	Up-regulation
CAMK_MAPKAPK_MK2_MAPKAPK2_ST	P49815	TSC2	P49137	MAPKAPK2	S1155	S1152C	1152	Missense	distal	-3	no	14.029	11.958	EPSD	COSMIC	11.681	Down-regulation
CAMK_MAPKAPK_MK2_MAPKAPK2_ST	P49815	TSC2	P49137	MAPKAPK2	S1254	A1257V	1257	Missense	distal	3	no	15.117	15.012	PhosphoSitePlus	COSMIC	11.681	Down-regulation
CAMK_MAPKAPK_MK2_MAPKAPK2_ST	P49815	TSC2	P49137	MAPKAPK2	S1254	S1252C	1252	Missense	proximal	-2	no	15.117	11.638	PhosphoSitePlus	COSMIC	11.681	Loss
CAMK_MAPKAPK_MK2_MAPKAPK2_ST	P49815	TSC2	P49137	MAPKAPK2	S1254	A1257E	1257	Missense	distal	3	no	15.117	15.055	PhosphoSitePlus	COSMIC	11.681	Down-regulation
CAMK_MAPKAPK_MK2_MAPKAPK2_ST	P49815	TSC2	P49137	MAPKAPK2	S1259	A1257V	1257	Missense	proximal	-2	no	12.844	10.644	EPSD	COSMIC	11.681	Loss
CAMK_MAPKAPK_MK2_MAPKAPK2_ST	P49815	TSC2	P49137	MAPKAPK2	S1259	S1252C	1252	Missense	distal	-7	no	12.844	12.889	EPSD	COSMIC	11.681	Up-regulation
CAMK_MAPKAPK_MK2_MAPKAPK2_ST	P49815	TSC2	P49137	MAPKAPK2	S1259	P1265S	1265	Missense	distal	6	no	12.844	12.861	EPSD	COSMIC	11.681	Up-regulation
CAMK_MAPKAPK_MK2_MAPKAPK2_ST	P49815	TSC2	P49137	MAPKAPK2	S1259	A1257E	1257	Missense	proximal	-2	no	12.844	10.995	EPSD	COSMIC	11.681	Loss
CAMK_MAPKAPK_MK2_MAPKAPK2_ST	P49815	TSC2	P49137	MAPKAPK2	S1259	K1262N	1262	Missense	distal	3	no	12.844	12.831	EPSD	COSMIC	11.681	Down-regulation
CAMK_MAPKAPK_MK2_MAPKAPK2_ST	P49815	TSC2	P49137	MAPKAPK2	S1269	S1274P	1274	Missense	distal	5	no	11.620	11.702	EPSD	COSMIC	11.681	Gain
CAMK_MAPKAPK_MK2_MAPKAPK2_ST	P49815	TSC2	P49137	MAPKAPK2	S1269	S1274N	1274	Missense	distal	5	no	11.620	11.859	EPSD	COSMIC	11.681	Gain
CAMK_MAPKAPK_MK2_MAPKAPK2_ST	P49815	TSC2	P49137	MAPKAPK2	T1271	P1265S	1265	Missense	distal	-6	no	17.058	17.057	EPSD	COSMIC	11.681	Down-regulation
CAMK_MAPKAPK_MK2_MAPKAPK2_ST	P49815	TSC2	P49137	MAPKAPK2	T1271	L1278M	1278	Missense	distal	7	no	17.058	17.269	EPSD	COSMIC	11.681	Up-regulation
CAMK_MAPKAPK_MK2_MAPKAPK2_ST	P49815	TSC2	P49137	MAPKAPK2	T1271	S1274P	1274	Missense	distal	3	no	17.058	17.051	EPSD	COSMIC	11.681	Down-regulation
CAMK_MAPKAPK_MK2_MAPKAPK2_ST	P49815	TSC2	P49137	MAPKAPK2	T1271	A1273V	1273	Missense	proximal	2	no	17.058	16.752	EPSD	COSMIC	11.681	Down-regulation
CAMK_MAPKAPK_MK2_MAPKAPK2_ST	P49815	TSC2	P49137	MAPKAPK2	T1271	R1268G	1268	Missense	distal	-3	no	17.058	6.398	EPSD	COSMIC	11.681	Loss
CAMK_MAPKAPK_MK2_MAPKAPK2_ST	P49815	TSC2	P49137	MAPKAPK2	T1271	S1276L	1276	Missense	distal	5	no	17.058	17.227	EPSD	COSMIC	11.681	Up-regulation
CAMK_MAPKAPK_MK2_MAPKAPK2_ST	P49815	TSC2	P49137	MAPKAPK2	T1271	S1274N	1274	Missense	distal	3	no	17.058	16.901	EPSD	COSMIC	11.681	Down-regulation
CAMK_MAPKAPK_MK2_MAPKAPK2_ST	P49815	TSC2	P49137	MAPKAPK2	T1271	S1269L	1269	Missense	proximal	-2	no	17.058	13.700	EPSD	COSMIC	11.681	Down-regulation
CAMK_MAPKAPK_MK2_MAPKAPK2_ST	P49815	TSC2	P49137	MAPKAPK2	S1336	S1334C	1334	Missense	proximal	-2	no	12.197	8.719	EPSD	COSMIC	11.681	Loss
CAMK_MAPKAPK_MK2_MAPKAPK2_ST	P49815	TSC2	P49137	MAPKAPK2	S1336	S1341F	1341	Missense	distal	5	no	12.197	12.585	EPSD	COSMIC	11.681	Up-regulation
CAMK_MAPKAPK_MK2_MAPKAPK2_ST	P49815	TSC2	P49137	MAPKAPK2	S1336	R1329H	1329	Missense	distal	-7	no	12.197	12.288	EPSD	COSMIC;GDSC	11.681	Up-regulation
CAMK_MAPKAPK_MK2_MAPKAPK2_ST	P49815	TSC2	P49137	MAPKAPK2	S1336	A1332V	1332	Missense	distal	-4	no	12.197	12.276	EPSD	COSMIC	11.681	Up-regulation
CAMK_MAPKAPK_MK2_MAPKAPK2_ST	P49815	TSC2	P49137	MAPKAPK2	S1336	T1330M	1330	Missense	distal	-6	no	12.197	12.253	EPSD	COSMIC	11.681	Up-regulation
CAMK_MAPKAPK_MK2_MAPKAPK2_ST	P49815	TSC2	P49137	MAPKAPK2	S1336	S1334R	1334	Missense	proximal	-2	no	12.197	9.930	EPSD	COSMIC	11.681	Loss
CAMK_MAPKAPK_MK2_MAPKAPK2_ST	P49815	TSC2	P49137	MAPKAPK2	S1336	R1335Q	1335	Missense	proximal	-1	no	12.197	12.221	EPSD	COSMIC	11.681	Up-regulation
CAMK_MAPKAPK_MK2_MAPKAPK2_ST	P49815	TSC2	P49137	MAPKAPK2	S1337	S1334R	1334	Missense	distal	-3	no	10.849	17.179	EPSD	COSMIC	11.681	Gain
CAMK_MAPKAPK_MK2_MAPKAPK2_ST	P49815	TSC2	P49137	MAPKAPK2	S1338	S1334C	1334	Missense	distal	-4	no	19.408	19.648	EPSD	COSMIC	11.681	Up-regulation
CAMK_MAPKAPK_MK2_MAPKAPK2_ST	P49815	TSC2	P49137	MAPKAPK2	S1338	S1341F	1341	Missense	distal	3	no	19.408	19.197	EPSD	COSMIC	11.681	Down-regulation
CAMK_MAPKAPK_MK2_MAPKAPK2_ST	P49815	TSC2	P49137	MAPKAPK2	S1338	A1332V	1332	Missense	distal	-6	no	19.408	19.438	EPSD	COSMIC	11.681	Up-regulation
CAMK_MAPKAPK_MK2_MAPKAPK2_ST	P49815	TSC2	P49137	MAPKAPK2	S1338	E1344D	1344	Missense	distal	6	no	19.408	19.394	EPSD	COSMIC	11.681	Down-regulation
CAMK_MAPKAPK_MK2_MAPKAPK2_ST	P49815	TSC2	P49137	MAPKAPK2	S1338	S1334R	1334	Missense	distal	-4	no	19.408	19.420	EPSD	COSMIC	11.681	Up-regulation
CAMK_MAPKAPK_MK2_MAPKAPK2_ST	P49815	TSC2	P49137	MAPKAPK2	S1338	R1335Q	1335	Missense	distal	-3	no	19.408	13.645	EPSD	COSMIC	11.681	Down-regulation
CAMK_MAPKAPK_MK2_MAPKAPK2_ST	P49815	TSC2	P49137	MAPKAPK2	S1340	S1334C	1334	Missense	distal	-6	no	13.750	13.813	EPSD	COSMIC	11.681	Up-regulation
CAMK_MAPKAPK_MK2_MAPKAPK2_ST	P49815	TSC2	P49137	MAPKAPK2	S1340	S1341F	1341	Missense	proximal	1	no	13.750	13.508	EPSD	COSMIC	11.681	Down-regulation
CAMK_MAPKAPK_MK2_MAPKAPK2_ST	P49815	TSC2	P49137	MAPKAPK2	S1340	E1344D	1344	Missense	distal	4	no	13.750	13.614	EPSD	COSMIC	11.681	Down-regulation
CAMK_MAPKAPK_MK2_MAPKAPK2_ST	P49815	TSC2	P49137	MAPKAPK2	S1340	S1334R	1334	Missense	distal	-6	no	13.750	13.763	EPSD	COSMIC	11.681	Up-regulation
CAMK_MAPKAPK_MK2_MAPKAPK2_ST	P49815	TSC2	P49137	MAPKAPK2	S1340	S1346C	1346	Missense	distal	6	no	13.750	13.722	EPSD	COSMIC	11.681	Down-regulation
CAMK_MAPKAPK_MK2_MAPKAPK2_ST	P49815	TSC2	P49137	MAPKAPK2	S1340	R1335Q	1335	Missense	distal	-5	no	13.750	13.033	EPSD	COSMIC	11.681	Down-regulation
CAMK_MAPKAPK_MK2_MAPKAPK2_ST	P49815	TSC2	P49137	MAPKAPK2	S1346	S1341F	1341	Missense	distal	-5	no	12.473	12.270	EPSD	COSMIC	11.681	Down-regulation
CAMK_MAPKAPK_MK2_MAPKAPK2_ST	P49815	TSC2	P49137	MAPKAPK2	S1346	E1344D	1344	Missense	proximal	-2	no	12.473	11.558	EPSD	COSMIC	11.681	Loss
CAMK_MAPKAPK_MK2_MAPKAPK2_ST	P49815	TSC2	P49137	MAPKAPK2	S1346	A1349S	1349	Missense	distal	3	no	12.473	12.428	EPSD	COSMIC	11.681	Down-regulation
CAMK_MAPKAPK_MK2_MAPKAPK2_ST	P49815	TSC2	P49137	MAPKAPK2	S1346	A1349V	1349	Missense	distal	3	no	12.473	12.369	EPSD	COSMIC;GDSC;CCLE	11.681	Down-regulation
CAMK_MAPKAPK_MK2_MAPKAPK2_ST	P49815	TSC2	P49137	MAPKAPK2	S1346	E1351K	1351	Missense	distal	5	no	12.473	12.687	EPSD	COSMIC	11.681	Up-regulation
CAMK_MAPKAPK_MK2_MAPKAPK2_ST	P49815	TSC2	P49137	MAPKAPK2	S1346	S1346C	1346	Missense	central	0	yes	12.473	0.000	EPSD	COSMIC	11.681	Loss
CAMK_MAPKAPK_MK2_MAPKAPK2_ST	P49815	TSC2	P49137	MAPKAPK2	S1364	S1365L	1365	Missense	proximal	1	no	14.445	14.646	EPSD	COSMIC	11.681	Up-regulation
CAMK_MAPKAPK_MK2_MAPKAPK2_ST	P49815	TSC2	P49137	MAPKAPK2	S1364	V1363M	1363	Missense	proximal	-1	no	14.445	14.451	EPSD	COSMIC	11.681	Up-regulation
CAMK_MAPKAPK_MK2_MAPKAPK2_ST	P49815	TSC2	P49137	MAPKAPK2	S1364	R1361Q	1361	Missense	distal	-3	no	14.445	8.681	EPSD	COSMIC	11.681	Loss
CAMK_MAPKAPK_MK2_MAPKAPK2_ST	P49815	TSC2	P49137	MAPKAPK2	S1364	G1367S	1367	Missense	distal	3	no	14.445	14.545	EPSD	COSMIC	11.681	Up-regulation
CAMK_MAPKAPK_MK2_MAPKAPK2_ST	P49815	TSC2	P49137	MAPKAPK2	S1364	S1364F	1364	Missense	central	0	yes	14.445	0.000	EPSD	COSMIC	11.681	Loss
CAMK_MAPKAPK_MK2_MAPKAPK2_ST	P49815	TSC2	P49137	MAPKAPK2	S1364	P1358H	1358	Missense	distal	-6	no	14.445	14.522	EPSD	COSMIC	11.681	Up-regulation
CAMK_MAPKAPK_MK2_MAPKAPK2_ST	P49815	TSC2	P49137	MAPKAPK2	S1364	S1371R	1371	Missense	distal	7	no	14.445	14.473	EPSD	COSMIC	11.681	Up-regulation
CAMK_MAPKAPK_MK2_MAPKAPK2_ST	P49815	TSC2	P49137	MAPKAPK2	S1364	S1364L	1364	Missense	central	0	yes	14.445	0.000	EPSD	COSMIC	11.681	Loss
CAMK_MAPKAPK_MK2_MAPKAPK2_ST	P49815	TSC2	P49137	MAPKAPK2	S1385	S1383C	1383	Missense	proximal	-2	no	11.883	8.405	EPSD	COSMIC	11.681	Loss
CAMK_MAPKAPK_MK2_MAPKAPK2_ST	P49815	TSC2	P49137	MAPKAPK2	S1385	S1383N	1383	Missense	proximal	-2	no	11.883	9.519	EPSD	COSMIC	11.681	Loss
CAMK_MAPKAPK_MK2_MAPKAPK2_ST	P49815	TSC2	P49137	MAPKAPK2	S1385	S1387L	1387	Missense	proximal	2	no	11.883	11.469	EPSD	COSMIC	11.681	Loss
CAMK_MAPKAPK_MK2_MAPKAPK2_ST	P49815	TSC2	P49137	MAPKAPK2	S1385	S1383R	1383	Missense	proximal	-2	no	11.883	9.617	EPSD	COSMIC	11.681	Loss
CAMK_MAPKAPK_MK2_MAPKAPK2_ST	P49815	TSC2	P49137	MAPKAPK2	S1385	S1379L	1379	Missense	distal	-6	no	11.883	11.915	EPSD	COSMIC	11.681	Up-regulation
CAMK_MAPKAPK_MK2_MAPKAPK2_ST	P49815	TSC2	P49137	MAPKAPK2	S1385	E1390G	1390	Missense	distal	5	no	11.883	12.081	EPSD	COSMIC	11.681	Up-regulation
CAMK_MAPKAPK_MK2_MAPKAPK2_ST	P49815	TSC2	P49137	MAPKAPK2	S1385	P1389H	1389	Missense	distal	4	no	11.883	11.640	EPSD	COSMIC	11.681	Loss
CAMK_MAPKAPK_MK2_MAPKAPK2_ST	P49815	TSC2	P49137	MAPKAPK2	S1385	S1385F	1385	Missense	central	0	yes	11.883	0.000	EPSD	COSMIC	11.681	Loss
CAMK_MAPKAPK_MK2_MAPKAPK2_ST	P49815	TSC2	P49137	MAPKAPK2	S1385	E1390D	1390	Missense	distal	5	no	11.883	12.065	EPSD	COSMIC	11.681	Up-regulation
CAMK_MAPKAPK_MK2_MAPKAPK2_ST	P49815	TSC2	P49137	MAPKAPK2	S1386	S1383R	1383	Missense	distal	-3	no	9.016	15.345	EPSD	COSMIC	11.681	Gain
CAMK_MAPKAPK_MK2_MAPKAPK2_ST	P49815	TSC2	P49137	MAPKAPK2	S1387	S1383C	1383	Missense	distal	-4	no	13.645	13.884	EPSD	COSMIC	11.681	Up-regulation
CAMK_MAPKAPK_MK2_MAPKAPK2_ST	P49815	TSC2	P49137	MAPKAPK2	S1387	S1383N	1383	Missense	distal	-4	no	13.645	13.866	EPSD	COSMIC	11.681	Up-regulation
CAMK_MAPKAPK_MK2_MAPKAPK2_ST	P49815	TSC2	P49137	MAPKAPK2	S1387	S1387L	1387	Missense	central	0	yes	13.645	0.000	EPSD	COSMIC	11.681	Loss
CAMK_MAPKAPK_MK2_MAPKAPK2_ST	P49815	TSC2	P49137	MAPKAPK2	S1387	S1383R	1383	Missense	distal	-4	no	13.645	13.656	EPSD	COSMIC	11.681	Up-regulation
CAMK_MAPKAPK_MK2_MAPKAPK2_ST	P49815	TSC2	P49137	MAPKAPK2	S1387	E1390G	1390	Missense	distal	3	no	13.645	13.561	EPSD	COSMIC	11.681	Down-regulation
CAMK_MAPKAPK_MK2_MAPKAPK2_ST	P49815	TSC2	P49137	MAPKAPK2	S1387	P1389H	1389	Missense	proximal	2	no	13.645	13.222	EPSD	COSMIC	11.681	Down-regulation
CAMK_MAPKAPK_MK2_MAPKAPK2_ST	P49815	TSC2	P49137	MAPKAPK2	S1387	S1385F	1385	Missense	proximal	-2	no	13.645	8.219	EPSD	COSMIC	11.681	Loss
CAMK_MAPKAPK_MK2_MAPKAPK2_ST	P49815	TSC2	P49137	MAPKAPK2	S1387	E1390D	1390	Missense	distal	3	no	13.645	13.552	EPSD	COSMIC	11.681	Down-regulation
CAMK_MAPKAPK_MK2_MAPKAPK2_ST	P49815	TSC2	P49137	MAPKAPK2	S1388	S1383C	1383	Missense	distal	-5	no	12.312	11.861	EPSD	COSMIC	11.681	Down-regulation
CAMK_MAPKAPK_MK2_MAPKAPK2_ST	P49815	TSC2	P49137	MAPKAPK2	S1388	S1383N	1383	Missense	distal	-5	no	12.312	11.615	EPSD	COSMIC	11.681	Loss
CAMK_MAPKAPK_MK2_MAPKAPK2_ST	P49815	TSC2	P49137	MAPKAPK2	S1388	S1387L	1387	Missense	proximal	-1	no	12.312	12.313	EPSD	COSMIC	11.681	Up-regulation
CAMK_MAPKAPK_MK2_MAPKAPK2_ST	P49815	TSC2	P49137	MAPKAPK2	S1388	S1383R	1383	Missense	distal	-5	no	12.312	12.465	EPSD	COSMIC	11.681	Up-regulation
CAMK_MAPKAPK_MK2_MAPKAPK2_ST	P49815	TSC2	P49137	MAPKAPK2	S1388	E1390G	1390	Missense	proximal	2	no	12.312	12.086	EPSD	COSMIC	11.681	Down-regulation
CAMK_MAPKAPK_MK2_MAPKAPK2_ST	P49815	TSC2	P49137	MAPKAPK2	S1388	P1389H	1389	Missense	proximal	1	no	12.312	11.837	EPSD	COSMIC	11.681	Down-regulation
CAMK_MAPKAPK_MK2_MAPKAPK2_ST	P49815	TSC2	P49137	MAPKAPK2	S1388	S1385F	1385	Missense	distal	-3	no	12.312	7.437	EPSD	COSMIC	11.681	Loss
CAMK_MAPKAPK_MK2_MAPKAPK2_ST	P49815	TSC2	P49137	MAPKAPK2	S1388	E1390D	1390	Missense	proximal	2	no	12.312	12.068	EPSD	COSMIC	11.681	Down-regulation
CAMK_MAPKAPK_MK2_MAPKAPK2_ST	P49815	TSC2	P49137	MAPKAPK2	S1418	E1413D	1413	Missense	distal	-5	no	12.237	11.512	EPSD	COSMIC	11.681	Loss
CAMK_MAPKAPK_MK2_MAPKAPK2_ST	P49815	TSC2	P49137	MAPKAPK2	S1418	P1412T	1412	Missense	distal	-6	no	12.237	12.221	EPSD	COSMIC	11.681	Down-regulation
CAMK_MAPKAPK_MK2_MAPKAPK2_ST	P49815	TSC2	P49137	MAPKAPK2	S1418	S1420C	1420	Missense	proximal	2	no	12.237	11.837	EPSD	COSMIC	11.681	Down-regulation
CAMK_MAPKAPK_MK2_MAPKAPK2_ST	P49815	TSC2	P49137	MAPKAPK2	S1420	E1413D	1413	Missense	distal	-7	no	18.558	18.597	EPSD	COSMIC	11.681	Up-regulation
CAMK_MAPKAPK_MK2_MAPKAPK2_ST	P49815	TSC2	P49137	MAPKAPK2	S1420	S1427R	1427	Missense	distal	7	no	18.558	18.586	EPSD	COSMIC	11.681	Up-regulation
CAMK_MAPKAPK_MK2_MAPKAPK2_ST	P49815	TSC2	P49137	MAPKAPK2	S1420	S1420C	1420	Missense	central	0	yes	18.558	0.000	EPSD	COSMIC	11.681	Loss
CAMK_MAPKAPK_MK2_MAPKAPK2_ST	P49815	TSC2	P49137	MAPKAPK2	S1447	S1454N	1454	Missense	distal	7	no	11.840	11.550	EPSD	COSMIC	11.681	Loss
CAMK_MAPKAPK_MK2_MAPKAPK2_ST	P49815	TSC2	P49137	MAPKAPK2	S1447	P1446S	1446	Missense	proximal	-1	no	11.840	11.839	EPSD	COSMIC	11.681	Down-regulation
CAMK_MAPKAPK_MK2_MAPKAPK2_ST	P49815	TSC2	P49137	MAPKAPK2	S1447	S1454G	1454	Missense	distal	7	no	11.840	11.635	EPSD	COSMIC	11.681	Loss
CAMK_MAPKAPK_MK2_MAPKAPK2_ST	P49815	TSC2	P49137	MAPKAPK2	S1447	L1445M	1445	Missense	proximal	-2	no	11.840	13.072	EPSD	COSMIC	11.681	Up-regulation
CAMK_MAPKAPK_MK2_MAPKAPK2_ST	P49815	TSC2	P49137	MAPKAPK2	S1447	R1451I	1451	Missense	distal	4	no	11.840	11.717	EPSD	COSMIC	11.681	Down-regulation
CAMK_MAPKAPK_MK2_MAPKAPK2_ST	P49815	TSC2	P49137	MAPKAPK2	S1448	P1446S	1446	Missense	proximal	-2	no	9.090	12.321	EPSD	COSMIC	11.681	Gain
CAMK_MAPKAPK_MK2_MAPKAPK2_ST	P49815	TSC2	P49137	MAPKAPK2	S1449	S1454N	1454	Missense	distal	5	no	15.020	15.259	EPSD	COSMIC	11.681	Up-regulation
CAMK_MAPKAPK_MK2_MAPKAPK2_ST	P49815	TSC2	P49137	MAPKAPK2	S1449	P1446S	1446	Missense	distal	-3	no	15.020	13.355	EPSD	COSMIC	11.681	Down-regulation
CAMK_MAPKAPK_MK2_MAPKAPK2_ST	P49815	TSC2	P49137	MAPKAPK2	S1449	S1454G	1454	Missense	distal	5	no	15.020	15.309	EPSD	COSMIC	11.681	Up-regulation
CAMK_MAPKAPK_MK2_MAPKAPK2_ST	P49815	TSC2	P49137	MAPKAPK2	S1449	L1445M	1445	Missense	distal	-4	no	15.020	14.979	EPSD	COSMIC	11.681	Down-regulation
CAMK_MAPKAPK_MK2_MAPKAPK2_ST	P49815	TSC2	P49137	MAPKAPK2	S1449	R1451I	1451	Missense	proximal	2	no	15.020	14.707	EPSD	COSMIC	11.681	Down-regulation
CAMK_MAPKAPK_MK2_MAPKAPK2_ST	P49815	TSC2	P49137	MAPKAPK2	S1454	S1454N	1454	Missense	central	0	yes	18.407	0.000	EPSD	COSMIC	11.681	Loss
CAMK_MAPKAPK_MK2_MAPKAPK2_ST	P49815	TSC2	P49137	MAPKAPK2	S1454	Y1461H	1461	Missense	distal	7	no	18.407	18.465	EPSD	COSMIC	11.681	Up-regulation
CAMK_MAPKAPK_MK2_MAPKAPK2_ST	P49815	TSC2	P49137	MAPKAPK2	S1454	R1459Q	1459	Missense	distal	5	no	18.407	18.626	EPSD	COSMIC	11.681	Up-regulation
CAMK_MAPKAPK_MK2_MAPKAPK2_ST	P49815	TSC2	P49137	MAPKAPK2	S1454	S1454G	1454	Missense	central	0	yes	18.407	0.000	EPSD	COSMIC	11.681	Loss
CAMK_MAPKAPK_MK2_MAPKAPK2_ST	P49815	TSC2	P49137	MAPKAPK2	S1454	R1451I	1451	Missense	distal	-3	no	18.407	13.118	EPSD	COSMIC	11.681	Down-regulation
CAMK_MAPKAPK_MK2_MAPKAPK2_ST	P49815	TSC2	P49137	MAPKAPK2	T1462	S1464F	1464	Missense	proximal	2	no	14.028	13.313	EPSD	COSMIC	11.681	Down-regulation
CAMK_MAPKAPK_MK2_MAPKAPK2_ST	P49815	TSC2	P49137	MAPKAPK2	T1462	S1464Y	1464	Missense	proximal	2	no	14.028	13.338	EPSD	COSMIC	11.681	Down-regulation
CAMK_MAPKAPK_MK2_MAPKAPK2_ST	P49815	TSC2	P49137	MAPKAPK2	T1462	Y1461H	1461	Missense	proximal	-1	no	14.028	14.022	EPSD	COSMIC	11.681	Down-regulation
CAMK_MAPKAPK_MK2_MAPKAPK2_ST	P49815	TSC2	P49137	MAPKAPK2	T1462	R1459Q	1459	Missense	distal	-3	no	14.028	8.264	EPSD	COSMIC	11.681	Loss
CAMK_MAPKAPK_MK2_MAPKAPK2_ST	P49815	TSC2	P49137	MAPKAPK2	T1462	I1463N	1463	Missense	proximal	1	no	14.028	13.447	EPSD	COSMIC	11.681	Down-regulation
CAMK_MAPKAPK_MK2_MAPKAPK2_ST	P49815	TSC2	P49137	MAPKAPK2	T1462	D1465N	1465	Missense	distal	3	no	14.028	13.981	EPSD	COSMIC	11.681	Down-regulation
CAMK_MAPKAPK_MK2_MAPKAPK2_ST	P49815	TSC2	P49137	MAPKAPK2	T1462	P1468T	1468	Missense	distal	6	no	14.028	14.042	EPSD	COSMIC	11.681	Up-regulation
CAMK_MAPKAPK_MK2_MAPKAPK2_ST	P49815	TSC2	P49137	MAPKAPK2	T1462	T1462I	1462	Missense	central	0	yes	14.028	0.000	EPSD	COSMIC	11.681	Loss
CAMK_MAPKAPK_MK2_MAPKAPK2_ST	P49815	TSC2	P49137	MAPKAPK2	T1462	S1464C	1464	Missense	proximal	2	no	14.028	13.628	EPSD	COSMIC	11.681	Down-regulation
CAMK_MAPKAPK_MK2_MAPKAPK2_ST	P49815	TSC2	P49137	MAPKAPK2	S1464	S1464F	1464	Missense	central	0	yes	13.136	0.000	EPSD	COSMIC	11.681	Loss
CAMK_MAPKAPK_MK2_MAPKAPK2_ST	P49815	TSC2	P49137	MAPKAPK2	S1464	S1464Y	1464	Missense	central	0	yes	13.136	0.000	EPSD	COSMIC	11.681	Loss
CAMK_MAPKAPK_MK2_MAPKAPK2_ST	P49815	TSC2	P49137	MAPKAPK2	S1464	Y1461H	1461	Missense	distal	-3	no	13.136	14.118	EPSD	COSMIC	11.681	Up-regulation
CAMK_MAPKAPK_MK2_MAPKAPK2_ST	P49815	TSC2	P49137	MAPKAPK2	S1464	R1459Q	1459	Missense	distal	-5	no	13.136	12.418	EPSD	COSMIC	11.681	Down-regulation
CAMK_MAPKAPK_MK2_MAPKAPK2_ST	P49815	TSC2	P49137	MAPKAPK2	S1464	I1463N	1463	Missense	proximal	-1	no	13.136	13.149	EPSD	COSMIC	11.681	Up-regulation
CAMK_MAPKAPK_MK2_MAPKAPK2_ST	P49815	TSC2	P49137	MAPKAPK2	S1464	R1471M	1471	Missense	distal	7	no	13.136	12.963	EPSD	COSMIC	11.681	Down-regulation
CAMK_MAPKAPK_MK2_MAPKAPK2_ST	P49815	TSC2	P49137	MAPKAPK2	S1464	R1470H	1470	Missense	distal	6	no	13.136	13.105	EPSD	COSMIC	11.681	Down-regulation
CAMK_MAPKAPK_MK2_MAPKAPK2_ST	P49815	TSC2	P49137	MAPKAPK2	S1464	D1465N	1465	Missense	proximal	1	no	13.136	13.004	EPSD	COSMIC	11.681	Down-regulation
CAMK_MAPKAPK_MK2_MAPKAPK2_ST	P49815	TSC2	P49137	MAPKAPK2	S1464	P1468T	1468	Missense	distal	4	no	13.136	13.243	EPSD	COSMIC	11.681	Up-regulation
CAMK_MAPKAPK_MK2_MAPKAPK2_ST	P49815	TSC2	P49137	MAPKAPK2	S1464	T1462I	1462	Missense	proximal	-2	no	13.136	10.549	EPSD	COSMIC	11.681	Loss
CAMK_MAPKAPK_MK2_MAPKAPK2_ST	P49815	TSC2	P49137	MAPKAPK2	S1464	S1464C	1464	Missense	central	0	yes	13.136	0.000	EPSD	COSMIC	11.681	Loss
CAMK_MAPKAPK_MK2_MAPKAPK2_ST	P49815	TSC2	P49137	MAPKAPK2	S1466	S1464F	1464	Missense	proximal	-2	no	13.799	8.373	EPSD	COSMIC	11.681	Loss
CAMK_MAPKAPK_MK2_MAPKAPK2_ST	P49815	TSC2	P49137	MAPKAPK2	S1466	S1464Y	1464	Missense	proximal	-2	no	13.799	8.928	EPSD	COSMIC	11.681	Loss
CAMK_MAPKAPK_MK2_MAPKAPK2_ST	P49815	TSC2	P49137	MAPKAPK2	S1466	Y1461H	1461	Missense	distal	-5	no	13.799	14.295	EPSD	COSMIC	11.681	Up-regulation
CAMK_MAPKAPK_MK2_MAPKAPK2_ST	P49815	TSC2	P49137	MAPKAPK2	S1466	R1459Q	1459	Missense	distal	-7	no	13.799	13.886	EPSD	COSMIC	11.681	Up-regulation
CAMK_MAPKAPK_MK2_MAPKAPK2_ST	P49815	TSC2	P49137	MAPKAPK2	S1466	I1463N	1463	Missense	distal	-3	no	13.799	12.542	EPSD	COSMIC	11.681	Down-regulation
CAMK_MAPKAPK_MK2_MAPKAPK2_ST	P49815	TSC2	P49137	MAPKAPK2	S1466	R1471M	1471	Missense	distal	5	no	13.799	13.918	EPSD	COSMIC	11.681	Up-regulation
CAMK_MAPKAPK_MK2_MAPKAPK2_ST	P49815	TSC2	P49137	MAPKAPK2	S1466	R1470H	1470	Missense	distal	4	no	13.799	13.561	EPSD	COSMIC	11.681	Down-regulation
CAMK_MAPKAPK_MK2_MAPKAPK2_ST	P49815	TSC2	P49137	MAPKAPK2	S1466	D1465N	1465	Missense	proximal	-1	no	13.799	13.801	EPSD	COSMIC	11.681	Up-regulation
CAMK_MAPKAPK_MK2_MAPKAPK2_ST	P49815	TSC2	P49137	MAPKAPK2	S1466	P1468T	1468	Missense	proximal	2	no	13.799	14.015	EPSD	COSMIC	11.681	Up-regulation
CAMK_MAPKAPK_MK2_MAPKAPK2_ST	P49815	TSC2	P49137	MAPKAPK2	S1466	T1462I	1462	Missense	distal	-4	no	13.799	13.932	EPSD	COSMIC	11.681	Up-regulation
CAMK_MAPKAPK_MK2_MAPKAPK2_ST	P49815	TSC2	P49137	MAPKAPK2	S1466	S1464C	1464	Missense	proximal	-2	no	13.799	10.321	EPSD	COSMIC	11.681	Loss
CAMK_MAPKAPK_MK2_MAPKAPK2_ST	P49815	TSC2	P49137	MAPKAPK2	S1730	R1729C	1729	Missense	proximal	-1	no	14.551	14.572	EPSD	COSMIC	11.681	Up-regulation
CAMK_MAPKAPK_MK2_MAPKAPK2_ST	P49815	TSC2	P49137	MAPKAPK2	S1730	R1729H	1729	Missense	proximal	-1	no	14.551	14.574	EPSD	COSMIC	11.681	Up-regulation
CAMK_MAPKAPK_MK2_MAPKAPK2_ST	P49815	TSC2	P49137	MAPKAPK2	S1730	P1737L	1737	Missense	distal	7	no	14.551	14.078	EPSD	COSMIC	11.681	Down-regulation
CAMK_MAPKAPK_MK2_MAPKAPK2_ST	P49815	TSC2	P49137	MAPKAPK2	S1730	T1733A	1733	Missense	distal	3	no	14.551	14.523	EPSD	COSMIC	11.681	Down-regulation
CAMK_MAPKAPK_MK2_MAPKAPK2_ST	P49815	TSC2	P49137	MAPKAPK2	S1730	H1726N	1726	Missense	distal	-4	no	14.551	14.521	EPSD	COSMIC	11.681	Down-regulation
CAMK_MAPKAPK_MK2_MAPKAPK2_ST	P49815	TSC2	P49137	MAPKAPK2	S1730	R1729S	1729	Missense	proximal	-1	no	14.551	14.561	EPSD	COSMIC	11.681	Up-regulation
CAMK_MAPKAPK_MK2_MAPKAPK2_ST	P49815	TSC2	P49137	MAPKAPK2	S1730	S1730F	1730	Missense	central	0	yes	14.551	0.000	EPSD	COSMIC	11.681	Loss
CAMK_MAPKAPK_MK2_MAPKAPK2_ST	P49815	TSC2	P49137	MAPKAPK2	S1730	S1730C	1730	Missense	central	0	yes	14.551	0.000	EPSD	COSMIC	11.681	Loss
CAMK_MAPKAPK_MK2_MAPKAPK2_ST	P49815	TSC2	P49137	MAPKAPK2	S1730	S1728P	1728	Missense	proximal	-2	no	14.551	11.320	EPSD	COSMIC	11.681	Loss
CAMK_MAPKAPK_MK2_MAPKAPK2_ST	P49815	TSC2	P49137	MAPKAPK2	S1730	P1732S	1732	Missense	proximal	2	no	14.551	14.743	EPSD	COSMIC	11.681	Up-regulation
CAMK_MAPKAPK_MK2_MAPKAPK2_ST	P49815	TSC2	P49137	MAPKAPK2	S1772	S1774T	1774	Missense	proximal	2	no	11.911	11.934	EPSD	COSMIC	11.681	Up-regulation
CAMK_MAPKAPK_MK2_MAPKAPK2_ST	P49815	TSC2	P49137	MAPKAPK2	S1772	P1770S	1770	Missense	proximal	-2	no	11.911	15.142	EPSD	COSMIC	11.681	Up-regulation
CAMK_MAPKAPK_MK2_MAPKAPK2_ST	P49815	TSC2	P49137	MAPKAPK2	S1772	P1771L	1771	Missense	proximal	-1	no	11.911	11.910	EPSD	COSMIC	11.681	Down-regulation
CAMK_MAPKAPK_MK2_MAPKAPK2_ST	P49815	TSC2	P49137	MAPKAPK2	S1772	A1778G	1778	Missense	distal	6	no	11.911	11.889	EPSD	COSMIC	11.681	Down-regulation
CAMK_MAPKAPK_MK2_MAPKAPK2_ST	P49815	TSC2	P49137	MAPKAPK2	S1772	A1776G	1776	Missense	distal	4	no	11.911	11.699	EPSD	COSMIC;GDSC;CCLE	11.681	Down-regulation
CAMK_MAPKAPK_MK2_MAPKAPK2_ST	P49815	TSC2	P49137	MAPKAPK2	S1774	P1781L	1781	Missense	distal	7	no	14.940	14.466	EPSD	COSMIC	11.681	Down-regulation
CAMK_MAPKAPK_MK2_MAPKAPK2_ST	P49815	TSC2	P49137	MAPKAPK2	S1774	P1770S	1770	Missense	distal	-4	no	14.940	14.860	EPSD	COSMIC	11.681	Down-regulation
CAMK_MAPKAPK_MK2_MAPKAPK2_ST	P49815	TSC2	P49137	MAPKAPK2	S1774	P1771L	1771	Missense	distal	-3	no	14.940	14.514	EPSD	COSMIC	11.681	Down-regulation
CAMK_MAPKAPK_MK2_MAPKAPK2_ST	P49815	TSC2	P49137	MAPKAPK2	S1774	A1778G	1778	Missense	distal	4	no	14.940	14.728	EPSD	COSMIC	11.681	Down-regulation
CAMK_MAPKAPK_MK2_MAPKAPK2_ST	P49815	TSC2	P49137	MAPKAPK2	S1774	S1772T	1772	Missense	proximal	-2	no	14.940	13.185	EPSD	COSMIC	11.681	Down-regulation
CAMK_MAPKAPK_MK2_MAPKAPK2_ST	P49815	TSC2	P49137	MAPKAPK2	S1774	A1776G	1776	Missense	proximal	2	no	14.940	14.534	EPSD	COSMIC;GDSC;CCLE	11.681	Down-regulation
CAMK_MAPKAPK_MK2_MAPKAPK2_ST	P49815	TSC2	P49137	MAPKAPK2	S1798	R1795H	1795	Missense	distal	-3	no	15.750	10.991	EPSD	COSMIC	11.681	Loss
CAMK_MAPKAPK_MK2_MAPKAPK2_ST	P49815	TSC2	P49137	MAPKAPK2	S1798	R1793Q	1793	Missense	distal	-5	no	15.750	15.032	EPSD	COSMIC	11.681	Down-regulation
CAMK_MAPKAPK_MK2_MAPKAPK2_ST	P49815	TSC2	P49137	MAPKAPK2	S1798	R1795C	1795	Missense	distal	-3	no	15.750	7.350	EPSD	COSMIC	11.681	Loss
CAMK_MAPKAPK_MK2_MAPKAPK2_ST	P49815	TSC2	P49137	MAPKAPK2	S1798	R1793W	1793	Missense	distal	-5	no	15.750	15.396	EPSD	COSMIC	11.681	Down-regulation
CAMK_MAPKAPK_MK2_MAPKAPK2_ST	P49815	TSC2	P49137	MAPKAPK2	S1798	G1791S	1791	Missense	distal	-7	no	15.750	15.692	EPSD	COSMIC	11.681	Down-regulation
CAMK_MAPKAPK_MK2_MAPKAPK2_ST	P49815	TSC2	P49137	MAPKAPK2	S1798	T1804I	1804	Missense	distal	6	no	15.750	15.727	EPSD	COSMIC	11.681	Down-regulation
CAMK_MAPKAPK_MK2_MAPKAPK2_ST	P49815	TSC2	P49137	MAPKAPK2	S1798	R1793H	1793	Missense	distal	-5	no	15.750	15.273	EPSD	COSMIC	11.681	Down-regulation
CAMK_MAPKAPK_MK2_MAPKAPK2_ST	P49815	TSC2	P49137	MAPKAPK2	S1798	R1793C	1793	Missense	distal	-5	no	15.750	15.145	EPSD	COSMIC	11.681	Down-regulation
CAMK_MAPKAPK_MK2_MAPKAPK2_ST	P30307	CDC25C	P49137	MAPKAPK2	S17	P19S	19	Missense	proximal	2	no	13.688	13.880	EPSD	COSMIC	11.681	Up-regulation
CAMK_MAPKAPK_MK2_MAPKAPK2_ST	P30307	CDC25C	P49137	MAPKAPK2	S216	S216L	216	Missense	central	0	yes	19.967	0.000	PhosphoSitePlus	COSMIC	11.681	Loss
CAMK_MAPKAPK_MK2_MAPKAPK2_ST	P30307	CDC25C	P49137	MAPKAPK2	S216	G210R	210	Missense	distal	-6	no	19.967	19.895	PhosphoSitePlus	COSMIC	11.681	Down-regulation
CAMK_MAPKAPK_MK2_MAPKAPK2_ST	P30307	CDC25C	P49137	MAPKAPK2	S247	Y245S	245	Missense	proximal	-2	no	7.312	12.183	EPSD	COSMIC	11.681	Gain
CAMK_MAPKAPK_MK2_MAPKAPK2_ST	P30307	CDC25C	P49137	MAPKAPK2	S449	R448Q	448	Missense	proximal	-1	no	13.827	13.852	EPSD	COSMIC	11.681	Up-regulation
CAMK_MAPKAPK_MK2_MAPKAPK2_ST	P30307	CDC25C	P49137	MAPKAPK2	S449	E443K	443	Missense	distal	-6	no	13.827	13.890	EPSD	COSMIC	11.681	Up-regulation
CAMK_MAPKAPK_MK2_MAPKAPK2_ST	P30307	CDC25C	P49137	MAPKAPK2	S451	R448Q	448	Missense	distal	-3	no	18.092	12.328	EPSD	COSMIC	11.681	Down-regulation
CAMK_MAPKAPK_MK2_MAPKAPK2_ST	Q14457	BECN1	P49137	MAPKAPK2	S64	E67K	67	Missense	distal	3	no	11.915	11.787	EPSD	COSMIC;GDSC	11.681	Down-regulation
CAMK_MAPKAPK_MK2_MAPKAPK2_ST	Q14457	BECN1	P49137	MAPKAPK2	S64	E61G	61	Missense	distal	-3	no	11.915	6.550	EPSD	COSMIC	11.681	Loss
CAMK_MAPKAPK_MK2_MAPKAPK2_ST	Q14457	BECN1	P49137	MAPKAPK2	S234	Q240H	240	Missense	distal	6	no	15.218	15.208	EPSD	COSMIC	11.681	Down-regulation
CAMK_MAPKAPK_MK2_MAPKAPK2_ST	P35900	KRT20	P49137	MAPKAPK2	S13	L12M	12	Missense	proximal	-1	no	19.361	19.369	PhosphoSitePlus	COSMIC	11.681	Up-regulation
CAMK_MAPKAPK_MK2_MAPKAPK2_ST	P35900	KRT20	P49137	MAPKAPK2	S15	L12M	12	Missense	distal	-3	no	13.805	10.505	EPSD	COSMIC	11.681	Loss
CAMK_MAPKAPK_MK2_MAPKAPK2_ST	P35900	KRT20	P49137	MAPKAPK2	T31	G38D	38	Missense	distal	7	no	13.404	13.496	EPSD	COSMIC	11.681	Up-regulation
CAMK_MAPKAPK_MK2_MAPKAPK2_ST	P35900	KRT20	P49137	MAPKAPK2	S34	G38D	38	Missense	distal	4	no	12.843	12.837	EPSD	COSMIC	11.681	Down-regulation
CAMK_MAPKAPK_MK2_MAPKAPK2_ST	P35900	KRT20	P49137	MAPKAPK2	S83	S83N	83	Missense	central	0	yes	13.206	0.000	EPSD	COSMIC	11.681	Loss
CAMK_MAPKAPK_MK2_MAPKAPK2_ST	P35900	KRT20	P49137	MAPKAPK2	S83	S83G	83	Missense	central	0	yes	13.206	0.000	EPSD	COSMIC	11.681	Loss
CAMK_MAPKAPK_MK2_MAPKAPK2_ST	P35900	KRT20	P49137	MAPKAPK2	S293	R291H	291	Missense	proximal	-2	no	17.428	14.997	EPSD	COSMIC	11.681	Down-regulation
CAMK_MAPKAPK_MK2_MAPKAPK2_ST	P35900	KRT20	P49137	MAPKAPK2	S293	E288Q	288	Missense	distal	-5	no	17.428	16.914	EPSD	COSMIC	11.681	Down-regulation
CAMK_MAPKAPK_MK2_MAPKAPK2_ST	P35900	KRT20	P49137	MAPKAPK2	S295	R291H	291	Missense	distal	-4	no	12.513	12.753	EPSD	COSMIC	11.681	Up-regulation
CAMK_MAPKAPK_MK2_MAPKAPK2_ST	P35900	KRT20	P49137	MAPKAPK2	S295	E288Q	288	Missense	distal	-7	no	12.513	12.565	EPSD	COSMIC	11.681	Up-regulation
CAMK_CAMKL_MARK_MARK3_ST	P27448	MARK3	P27448-3	MARK3	S368	E370Q	370	Missense	proximal	2	no	313.147	277.086	EPSD	COSMIC	255.132	Down-regulation
CAMK_CAMKL_MARK_MARK3_ST	P27448	MARK3	P27448-3	MARK3	S368	E370A	370	Missense	proximal	2	no	313.147	285.697	EPSD	COSMIC	255.132	Down-regulation
CAMK_CAMKL_MARK_MARK3_ST	P27448	MARK3	P27448-3	MARK3	S368	E370D	370	Missense	proximal	2	no	313.147	314.193	EPSD	COSMIC;GDSC	255.132	Up-regulation
CAMK_CAMKL_MARK_MARK3_ST	P27448	MARK3	P27448-3	MARK3	S369	E370Q	370	Missense	proximal	1	no	279.417	279.431	EPSD	COSMIC	255.132	Up-regulation
CAMK_CAMKL_MARK_MARK3_ST	P27448	MARK3	P27448-3	MARK3	S369	E370A	370	Missense	proximal	1	no	279.417	279.429	EPSD	COSMIC	255.132	Up-regulation
CAMK_CAMKL_MARK_MARK3_ST	P27448	MARK3	P27448-3	MARK3	S369	E370D	370	Missense	proximal	1	no	279.417	279.427	EPSD	COSMIC;GDSC	255.132	Up-regulation
CAMK_CAMKL_MARK_MARK3_ST	P27448	MARK3	P27448-3	MARK3	S383	S379I	379	Missense	distal	-4	no	295.051	291.237	EPSD	COSMIC	255.132	Down-regulation
CAMK_CAMKL_MARK_MARK3_ST	P27448	MARK3	P27448-3	MARK3	S383	S377G	377	Missense	distal	-6	no	295.051	294.627	EPSD	COSMIC	255.132	Down-regulation
CAMK_CAMKL_MARK_MARK3_ST	P27448	MARK3	P27448-3	MARK3	S390	T397S	397	Missense	distal	7	no	263.021	264.254	EPSD	COSMIC	255.132	Up-regulation
CAMK_CAMKL_MARK_MARK3_ST	P27448	MARK3	P27448-3	MARK3	S390	L393I	393	Missense	distal	3	no	263.021	263.241	EPSD	COSMIC	255.132	Up-regulation
CAMK_CAMKL_MARK_MARK3_ST	P27448	MARK3	P27448-3	MARK3	S391	T397S	397	Missense	distal	6	no	258.245	240.410	EPSD	COSMIC	255.132	Loss
CAMK_CAMKL_MARK_MARK3_ST	P27448	MARK3	P27448-3	MARK3	S391	L393I	393	Missense	proximal	2	no	258.245	234.979	EPSD	COSMIC	255.132	Loss
CAMK_CAMKL_MARK_MARK3_ST	P27448	MARK3	P27448-3	MARK3	S436	K434E	434	Missense	proximal	-2	no	265.635	247.910	EPSD	COSMIC	255.132	Loss
CAMK_CAMKL_MARK_MARK3_ST	P27448	MARK3	P27448-3	MARK3	S451	R453W	453	Missense	proximal	2	no	317.408	310.062	EPSD	COSMIC;GDSC;CCLE	255.132	Down-regulation
CAMK_CAMKL_MARK_MARK3_ST	P27448	MARK3	P27448-3	MARK3	S452	R453W	453	Missense	proximal	1	no	394.378	394.393	EPSD	COSMIC;GDSC;CCLE	255.132	Up-regulation
CAMK_CAMKL_MARK_MARK3_ST	P27448	MARK3	P27448-3	MARK3	S455	R453W	453	Missense	proximal	-2	no	258.075	246.158	EPSD	COSMIC;GDSC;CCLE	255.132	Loss
CAMK_CAMKL_MARK_MARK3_ST	P27448	MARK3	P27448-3	MARK3	S458	R453W	453	Missense	distal	-5	no	318.747	305.035	EPSD	COSMIC;GDSC;CCLE	255.132	Down-regulation
CAMK_CAMKL_MARK_MARK3_ST	P27448	MARK3	P27448-3	MARK3	S458	I465V	465	Missense	distal	7	no	318.747	319.041	EPSD	COSMIC	255.132	Up-regulation
CAMK_CAMKL_MARK_MARK3_ST	P27448	MARK3	P27448-3	MARK3	S469	I465V	465	Missense	distal	-4	no	343.219	340.125	EPSD	COSMIC	255.132	Down-regulation
CAMK_CAMKL_MARK_MARK3_ST	P27448	MARK3	P27448-3	MARK3	S499	P493H	493	Missense	distal	-6	no	263.040	265.233	EPSD	COSMIC	255.132	Up-regulation
CAMK_CAMKL_MARK_MARK3_ST	P27448	MARK3	P27448-3	MARK3	S499	S495N	495	Missense	distal	-4	no	263.040	274.923	EPSD	COSMIC	255.132	Up-regulation
CAMK_CAMKL_MARK_MARK3_ST	P27448	MARK3	P27448-3	MARK3	S529	T536S	536	Missense	distal	7	no	258.995	260.227	EPSD	COSMIC	255.132	Up-regulation
CAMK_CAMKL_MARK_MARK3_ST	P27448	MARK3	P27448-3	MARK3	S540	T536S	536	Missense	distal	-4	no	256.896	260.475	EPSD	COSMIC	255.132	Up-regulation
CAMK_CAMKL_MARK_MARK3_ST	P27448	MARK3	P27448-3	MARK3	T564	T559S	559	Missense	distal	-5	no	326.655	301.361	EPSD	COSMIC	255.132	Down-regulation
CAMK_CAMKL_MARK_MARK3_ST	P27448	MARK3	P27448-3	MARK3	T564	S563I	563	Missense	proximal	-1	no	326.655	326.702	EPSD	COSMIC	255.132	Up-regulation
CAMK_CAMKL_MARK_MARK3_ST	P27448	MARK3	P27448-3	MARK3	T564	R557Q	557	Missense	distal	-7	no	326.655	324.440	EPSD	COSMIC	255.132	Down-regulation
CAMK_CAMKL_MARK_MARK3_ST	P27448	MARK3	P27448-3	MARK3	T564	R557L	557	Missense	distal	-7	no	326.655	321.769	EPSD	COSMIC	255.132	Down-regulation
CAMK_CAMKL_MARK_MARK3_ST	P27448	MARK3	P27448-3	MARK3	T576	G579W	579	Missense	distal	3	no	260.044	259.576	EPSD	COSMIC	255.132	Down-regulation
CAMK_CAMKL_MARK_MARK3_ST	P27448	MARK3	P27448-3	MARK3	T591	P592L	592	Missense	proximal	1	no	257.916	257.909	EPSD	COSMIC	255.132	Down-regulation
CAMK_CAMKL_MARK_MARK3_ST	P27448	MARK3	P27448-3	MARK3	T591	A590T	590	Missense	proximal	-1	no	257.916	257.921	EPSD	COSMIC	255.132	Up-regulation
CAMK_CAMKL_MARK_MARK3_ST	P27448	MARK3	P27448-3	MARK3	S598	P592L	592	Missense	distal	-6	no	498.268	499.652	EPSD;PhosphoSitePlus	COSMIC	255.132	Up-regulation
CAMK_CAMKL_MARK_MARK3_ST	P27448	MARK3	P27448-3	MARK3	S598	L604P	604	Missense	distal	6	no	498.268	484.698	EPSD;PhosphoSitePlus	COSMIC	255.132	Down-regulation
CAMK_CAMKL_MARK_MARK3_ST	P27448	MARK3	P27448-3	MARK3	S601	L604P	604	Missense	distal	3	no	377.882	378.045	PhosphoSitePlus;EPSD	COSMIC	255.132	Up-regulation
CAMK_CAMKL_MARK_MARK3_ST	P27448	MARK3	P27448-3	MARK3	T602	L604P	604	Missense	proximal	2	no	369.966	411.644	EPSD;PhosphoSitePlus	COSMIC	255.132	Up-regulation
CAMK_CAMKL_MARK_MARK3_ST	P27448	MARK3	P27448-3	MARK3	S606	L604P	604	Missense	proximal	-2	no	332.106	331.269	EPSD;PhosphoSitePlus	COSMIC	255.132	Down-regulation
CAMK_CAMKL_MARK_MARK3_ST	P27448	MARK3	P27448-3	MARK3	T627	G633W	633	Missense	distal	6	no	339.169	332.592	EPSD	COSMIC	255.132	Down-regulation
CAMK_CAMKL_MARK_MARK3_ST	P27448	MARK3	P27448-3	MARK3	T627	P626Q	626	Missense	proximal	-1	no	339.169	339.857	EPSD	COSMIC	255.132	Up-regulation
CAMK_CAMKL_MARK_MARK3_ST	P27448	MARK3	P27448-3	MARK3	T627	T627A	627	Missense	central	0	yes	339.169	0.000	EPSD	COSMIC	255.132	Loss
CAMK_CAMKL_MARK_MARK3_ST	P27448	MARK3	P27448-3	MARK3	T627	R634K	634	Missense	distal	7	no	339.169	336.354	EPSD	COSMIC	255.132	Down-regulation
CAMK_CAMKL_MARK_MARK3_ST	P27448	MARK3	P27448-3	MARK3	S639	R634K	634	Missense	distal	-5	no	223.438	318.333	EPSD	COSMIC	255.132	Gain
CAMK_CAMKL_MARK_MARK3_ST	P27448	MARK3	P27448-3	MARK3	S663	R656C	656	Missense	distal	-7	no	360.773	356.322	EPSD	COSMIC	255.132	Down-regulation
CAMK_CAMKL_MARK_MARK3_ST	P27448	MARK3	P27448-3	MARK3	S663	L658P	658	Missense	distal	-5	no	360.773	252.870	EPSD	COSMIC	255.132	Loss
CAMK_CAMKL_MARK_MARK3_ST	P27448	MARK3	P27448-3	MARK3	S663	W662L	662	Missense	proximal	-1	no	360.773	360.498	EPSD	COSMIC	255.132	Down-regulation
CAMK_CAMKL_MARK_MARK3_ST	P27448	MARK3	P27448-3	MARK3	S663	R659C	659	Missense	distal	-4	no	360.773	353.977	EPSD	COSMIC	255.132	Down-regulation
CAMK_CAMKL_MARK_MARK3_ST	P27448	MARK3	P27448-3	MARK3	T666	D671E	671	Missense	distal	5	no	245.665	260.706	EPSD	COSMIC	255.132	Gain
CAMK_CAMKL_MARK_MARK3_ST	P27448	MARK3	P27448-3	MARK3	S668	D671E	671	Missense	distal	3	no	261.915	261.945	EPSD	COSMIC	255.132	Up-regulation
CAMK_CAMKL_MARK_MARK3_ST	P27448	MARK3	P27448-3	MARK3	S668	G673W	673	Missense	distal	5	no	261.915	270.387	EPSD	COSMIC	255.132	Up-regulation
CAMK_CAMKL_MARK_MARK3_ST	P27448	MARK3	P27448-3	MARK3	S668	W662L	662	Missense	distal	-6	no	261.915	261.770	EPSD	COSMIC	255.132	Down-regulation
CAMK_CAMKL_MARK_MARK3_ST	P27448	MARK3	P27448-3	MARK3	S668	D674G	674	Missense	distal	6	no	261.915	267.794	EPSD	COSMIC	255.132	Up-regulation
CAMK_CAMKL_MARK_MARK3_ST	P27448	MARK3	P27448-3	MARK3	S669	D671E	671	Missense	proximal	2	no	418.837	417.791	EPSD	COSMIC	255.132	Down-regulation
CAMK_CAMKL_MARK_MARK3_ST	P27448	MARK3	P27448-3	MARK3	S669	G673W	673	Missense	distal	4	no	418.837	418.562	EPSD	COSMIC	255.132	Down-regulation
CAMK_CAMKL_MARK_MARK3_ST	P27448	MARK3	P27448-3	MARK3	S669	W662L	662	Missense	distal	-7	no	418.837	418.849	EPSD	COSMIC	255.132	Up-regulation
CAMK_CAMKL_MARK_MARK3_ST	P27448	MARK3	P27448-3	MARK3	S669	D674G	674	Missense	distal	5	no	418.837	415.713	EPSD	COSMIC	255.132	Down-regulation
CAMK_CAMKL_MARK_MARK3_ST	P27448	MARK3	P27448-3	MARK3	S724	R729W	729	Missense	distal	5	no	353.601	344.387	EPSD	COSMIC	255.132	Down-regulation
CAMK_CAMKL_MARK_MARK3_ST	P27448	MARK3	P27448-3	MARK3	S724	R722I	722	Missense	proximal	-2	no	353.601	341.505	EPSD	COSMIC	255.132	Down-regulation
CAMK_CAMKL_MARK_MARK3_ST	P27448	MARK3	P27448-3	MARK3	S724	R722S	722	Missense	proximal	-2	no	353.601	337.281	EPSD	COSMIC	255.132	Down-regulation
CK1_CK1_CK1-G_CSNK1G2_ST	Q14457	BECN1	P78368	CSNK1G2	S7	K5R	5	Missense	proximal	-2	no	1.776	1.774	EPSD	COSMIC	1.578	Down-regulation
CK1_CK1_CK1-G_CSNK1G2_ST	Q14457	BECN1	P78368	CSNK1G2	T11	K5R	5	Missense	distal	-6	no	2.345	2.537	EPSD	COSMIC	1.578	Up-regulation
CK1_CK1_CK1-G_CSNK1G2_ST	Q14457	BECN1	P78368	CSNK1G2	T406	E404K	404	Missense	proximal	-2	no	7.721	7.735	EPSD;PhosphoSitePlus	COSMIC	1.578	Up-regulation
CK1_CK1_CK1-G_CSNK1G2_ST	Q14457	BECN1	P78368	CSNK1G2	S409	E404K	404	Missense	distal	-5	no	8.514	8.635	PhosphoSitePlus;EPSD	COSMIC	1.578	Up-regulation
CK1_CK1_CK1-G_CSNK1G2_ST	P84022	SMAD3	P78368	CSNK1G2	T8	P9L	9	Missense	proximal	1	no	3.665	3.575	EPSD	COSMIC	1.578	Down-regulation
CK1_CK1_CK1-G_CSNK1G2_ST	P84022	SMAD3	P78368	CSNK1G2	T8	I4V	4	Missense	distal	-4	no	3.665	3.701	EPSD	COSMIC	1.578	Up-regulation
CK1_CK1_CK1-G_CSNK1G2_ST	P84022	SMAD3	P78368	CSNK1G2	T388	S391R	391	Missense	distal	3	no	3.568	2.311	EPSD	COSMIC	1.578	Down-regulation
CK1_CK1_CK1-G_CSNK1G2_ST	P84022	SMAD3	P78368	CSNK1G2	T388	G381E	381	Missense	distal	-7	no	3.568	3.759	EPSD	COSMIC	1.578	Up-regulation
CK1_CK1_CK1-G_CSNK1G2_ST	O14654	IRS4	P78368	CSNK1G2	S66	R63W	63	Missense	distal	-3	no	3.144	3.115	EPSD	COSMIC	1.578	Down-regulation
CK1_CK1_CK1-G_CSNK1G2_ST	O14654	IRS4	P78368	CSNK1G2	S66	G61V	61	Missense	distal	-5	no	3.144	3.039	EPSD	COSMIC	1.578	Down-regulation
CK1_CK1_CK1-G_CSNK1G2_ST	O14654	IRS4	P78368	CSNK1G2	S68	R63W	63	Missense	distal	-5	no	1.608	1.611	EPSD	COSMIC	1.578	Up-regulation
CK1_CK1_CK1-G_CSNK1G2_ST	O14654	IRS4	P78368	CSNK1G2	S68	G61V	61	Missense	distal	-7	no	1.608	1.698	EPSD	COSMIC	1.578	Up-regulation
CK1_CK1_CK1-G_CSNK1G2_ST	O14654	IRS4	P78368	CSNK1G2	T208	A211S	211	Missense	distal	3	no	1.033	2.254	EPSD	COSMIC	1.578	Gain
CK1_CK1_CK1-G_CSNK1G2_ST	O14654	IRS4	P78368	CSNK1G2	S495	M488K	488	Missense	distal	-7	no	1.488	1.648	EPSD	COSMIC	1.578	Gain
CK1_CK1_CK1-G_CSNK1G2_ST	O14654	IRS4	P78368	CSNK1G2	S558	G557R	557	Missense	proximal	-1	no	1.678	1.037	EPSD	COSMIC	1.578	Loss
CK1_CK1_CK1-G_CSNK1G2_ST	O14654	IRS4	P78368	CSNK1G2	S558	G557V	557	Missense	proximal	-1	no	1.678	1.043	EPSD	COSMIC	1.578	Loss
CK1_CK1_CK1-G_CSNK1G2_ST	O14654	IRS4	P78368	CSNK1G2	S558	G559C	559	Missense	proximal	1	no	1.678	1.574	EPSD	COSMIC	1.578	Loss
CK1_CK1_CK1-G_CSNK1G2_ST	O14654	IRS4	P78368	CSNK1G2	S570	G571S	571	Missense	proximal	1	no	1.794	1.643	EPSD	COSMIC	1.578	Down-regulation
CK1_CK1_CK1-G_CSNK1G2_ST	O14654	IRS4	P78368	CSNK1G2	S570	G571R	571	Missense	proximal	1	no	1.794	1.656	EPSD	COSMIC	1.578	Down-regulation
CK1_CK1_CK1-G_CSNK1G2_ST	O14654	IRS4	P78368	CSNK1G2	T643	A640D	640	Missense	distal	-3	no	3.133	3.146	EPSD	COSMIC	1.578	Up-regulation
CK1_CK1_CK1-G_CSNK1G2_ST	O14654	IRS4	P78368	CSNK1G2	T643	A640G	640	Missense	distal	-3	no	3.133	3.170	EPSD	COSMIC	1.578	Up-regulation
CK1_CK1_CK1-G_CSNK1G2_ST	O14654	IRS4	P78368	CSNK1G2	T643	A640V	640	Missense	distal	-3	no	3.133	3.145	EPSD	COSMIC	1.578	Up-regulation
CK1_CK1_CK1-G_CSNK1G2_ST	O14654	IRS4	P78368	CSNK1G2	S804	S804R	804	Missense	central	0	yes	1.640	0.000	EPSD	COSMIC	1.578	Loss
CK1_CK1_CK1-G_CSNK1G2_ST	O14654	IRS4	P78368	CSNK1G2	S804	S804G	804	Missense	central	0	yes	1.640	0.000	EPSD	COSMIC	1.578	Loss
CK1_CK1_CK1-G_CSNK1G2_ST	O14654	IRS4	P78368	CSNK1G2	S804	S801P	801	Missense	distal	-3	no	1.640	1.623	EPSD	COSMIC	1.578	Down-regulation
AGC_PKC_PKCd_PRKCQ_ST	O94992	HEXIM1	Q04759	PRKCQ	S66	G63R	63	Missense	distal	-3	no	0.604	1.922	EPSD	COSMIC	1.204	Gain
AGC_PKC_PKCd_PRKCQ_ST	O94992	HEXIM1	Q04759	PRKCQ	S158	K159N	159	Missense	proximal	1	no	2.858	2.851	PhosphoSitePlus	COSMIC	1.204	Down-regulation
AGC_PKC_PKCd_PRKCQ_ST	P35241	RDX	Q04759	PRKCQ	S249	I245V	245	Missense	distal	-4	no	1.618	1.613	EPSD	COSMIC	1.204	Down-regulation
AGC_PKC_PKCd_PRKCQ_ST	P35241	RDX	Q04759	PRKCQ	T564	G571C	571	Missense	distal	7	no	1.468	1.462	PhosphoSitePlus	COSMIC	1.204	Down-regulation
AGC_PKC_PKCd_PRKCQ_ST	P35241	RDX	Q04759	PRKCQ	T564	R559C	559	Missense	distal	-5	no	1.468	1.206	PhosphoSitePlus	COSMIC	1.204	Down-regulation
AGC_PKC_PKCd_PRKCQ_ST	O15530	PDPK1	Q04759	PRKCQ	S6	V12M	12	Missense	distal	6	no	1.770	1.789	EPSD	COSMIC	1.204	Up-regulation
AGC_PKC_PKCd_PRKCQ_ST	O15530	PDPK1	Q04759	PRKCQ	S6	R3G	3	Missense	distal	-3	no	1.770	0.452	EPSD	COSMIC	1.204	Loss
AGC_PKC_PKCd_PRKCQ_ST	O15530	PDPK1	Q04759	PRKCQ	S241	Y248H	248	Missense	distal	7	no	1.793	1.786	PhosphoSitePlus;EPSD	COSMIC	1.204	Down-regulation
AGC_PKC_PKCd_PRKCQ_ST	O15530	PDPK1	Q04759	PRKCQ	S389	Q387R	387	Missense	proximal	-2	no	0.806	1.463	EPSD	COSMIC	1.204	Gain
AGC_PKC_PKCd_PRKCQ_ST	O15530	PDPK1	Q04759	PRKCQ	S390	Q387R	387	Missense	distal	-3	no	0.770	1.998	EPSD	COSMIC	1.204	Gain
AGC_PKC_PKCd_PRKCQ_ST	O15530	PDPK1	Q04759	PRKCQ	S410	G403W	403	Missense	distal	-7	no	1.791	1.790	EPSD	COSMIC	1.204	Down-regulation
AGC_PKC_PKCd_PRKCQ_ST	O15530	PDPK1	Q04759	PRKCQ	S410	G403E	403	Missense	distal	-7	no	1.791	1.792	EPSD	COSMIC	1.204	Up-regulation
AGC_PKC_PKCd_PRKCQ_ST	O15530	PDPK1	Q04759	PRKCQ	S410	G403S	403	Missense	distal	-7	no	1.791	1.787	EPSD	COSMIC	1.204	Down-regulation
AGC_PKC_PKCd_PRKCQ_ST	Q92934	BAD	Q04759	PRKCQ	S74	A78E	78	Missense	distal	4	no	1.454	1.416	EPSD	COSMIC	1.204	Down-regulation
AGC_PKC_PKCd_PRKCQ_ST	Q92934	BAD	Q04759	PRKCQ	S75	A78E	78	Missense	distal	3	no	2.338	2.332	PhosphoSitePlus;EPSD	COSMIC	1.204	Down-regulation
AGC_PKC_PKCd_PRKCQ_ST	Q92934	BAD	Q04759	PRKCQ	S97	P102L	102	Missense	distal	5	no	1.818	1.810	EPSD	COSMIC	1.204	Down-regulation
AGC_PKC_PKCd_PRKCQ_ST	Q92934	BAD	Q04759	PRKCQ	S97	S97P	97	Missense	central	0	yes	1.818	0.000	EPSD	COSMIC	1.204	Loss
AGC_PKC_PKCd_PRKCQ_ST	Q92934	BAD	Q04759	PRKCQ	S97	R98H	98	Missense	proximal	1	no	1.818	1.801	EPSD	COSMIC	1.204	Down-regulation
AGC_PKC_PKCd_PRKCQ_ST	Q92934	BAD	Q04759	PRKCQ	S97	P101S	101	Missense	distal	4	no	1.818	1.805	EPSD	COSMIC	1.204	Down-regulation
AGC_PKC_PKCd_PRKCQ_ST	Q92934	BAD	Q04759	PRKCQ	S99	P102L	102	Missense	distal	3	no	2.414	2.408	EPSD;PhosphoSitePlus	COSMIC	1.204	Down-regulation
AGC_PKC_PKCd_PRKCQ_ST	Q92934	BAD	Q04759	PRKCQ	S99	S97P	97	Missense	proximal	-2	no	2.414	2.486	EPSD;PhosphoSitePlus	COSMIC	1.204	Up-regulation
AGC_PKC_PKCd_PRKCQ_ST	Q92934	BAD	Q04759	PRKCQ	S99	R98H	98	Missense	proximal	-1	no	2.414	2.403	EPSD;PhosphoSitePlus	COSMIC	1.204	Down-regulation
AGC_PKC_PKCd_PRKCQ_ST	Q92934	BAD	Q04759	PRKCQ	S99	P101S	101	Missense	proximal	2	no	2.414	2.355	EPSD;PhosphoSitePlus	COSMIC	1.204	Down-regulation
AGC_PKC_PKCd_PRKCQ_ST	Q92934	BAD	Q04759	PRKCQ	S118	S124F	124	Missense	distal	6	no	2.130	2.118	EPSD	COSMIC	1.204	Down-regulation
AGC_PKC_PKCd_PRKCQ_ST	Q92934	BAD	Q04759	PRKCQ	S134	K127N	127	Missense	distal	-7	no	1.741	1.755	EPSD	COSMIC	1.204	Up-regulation
AGC_PKC_PKCd_PRKCQ_ST	Q92934	BAD	Q04759	PRKCQ	S134	K133N	133	Missense	proximal	-1	no	1.741	1.736	EPSD	COSMIC	1.204	Down-regulation
AGC_PKC_PKCd_PRKCQ_ST	Q92934	BAD	Q04759	PRKCQ	S144	W147R	147	Missense	distal	3	no	1.214	1.235	EPSD	COSMIC	1.204	Up-regulation
AGC_PKC_PKCd_PRKCQ_ST	Q92934	BAD	Q04759	PRKCQ	S145	W147R	147	Missense	proximal	2	no	2.381	2.646	EPSD	COSMIC	1.204	Up-regulation
AGC_PKC_PKCd_PRKCQ_ST	Q92934	BAD	Q04759	PRKCQ	S164	R161S	161	Missense	distal	-3	no	1.894	0.803	EPSD	COSMIC;GDSC	1.204	Loss
AGC_PKC_PKCd_PRKCQ_ST	Q92934	BAD	Q04759	PRKCQ	S164	P166S	166	Missense	proximal	2	no	1.894	1.835	EPSD	COSMIC	1.204	Down-regulation
AGC_PKC_PKCd_PRKCQ_ST	Q92934	BAD	Q04759	PRKCQ	S164	R161G	161	Missense	distal	-3	no	1.894	0.575	EPSD	COSMIC	1.204	Loss
AGC_PKC_PKCd_PRKCQ_ST	P15311	EZR	Q04759	PRKCQ	S249	R246K	246	Missense	distal	-3	no	1.607	1.189	EPSD	COSMIC	1.204	Loss
AGC_PKC_PKCd_PRKCQ_ST	P15311	EZR	Q04759	PRKCQ	S249	K253R	253	Missense	distal	4	no	1.607	1.670	EPSD	COSMIC;CCLE	1.204	Up-regulation
AGC_PKC_PKCd_PRKCQ_ST	P15311	EZR	Q04759	PRKCQ	T332	V333M	333	Missense	proximal	1	no	1.880	1.886	EPSD	COSMIC;CCLE	1.204	Up-regulation
AGC_PKC_PKCd_PRKCQ_ST	P15311	EZR	Q04759	PRKCQ	T332	V333L	333	Missense	proximal	1	no	1.880	1.881	EPSD	COSMIC	1.204	Up-regulation
AGC_PKC_PKCd_PRKCQ_ST	P15311	EZR	Q04759	PRKCQ	T332	E338G	338	Missense	distal	6	no	1.880	1.879	EPSD	COSMIC	1.204	Down-regulation
AGC_PKC_PKCd_PRKCQ_ST	Q04759	PRKCQ	Q04759	PRKCQ	S657	P653S	653	Missense	distal	-4	no	1.776	1.783	EPSD	COSMIC	1.204	Up-regulation
AGC_PKC_PKCd_PRKCQ_ST	Q04759	PRKCQ	Q04759	PRKCQ	S676	A678V	678	Missense	proximal	2	no	2.038	1.980	EPSD	COSMIC	1.204	Down-regulation
AGC_PKC_PKCd_PRKCQ_ST	Q04759	PRKCQ	Q04759	PRKCQ	S676	R674W	674	Missense	proximal	-2	no	2.038	1.324	EPSD	COSMIC;GDSC;CCLE	1.204	Down-regulation
AGC_PKC_PKCd_PRKCQ_ST	Q04759	PRKCQ	Q04759	PRKCQ	S676	R680K	680	Missense	distal	4	no	2.038	1.975	EPSD	COSMIC	1.204	Down-regulation
AGC_PKC_PKCd_PRKCQ_ST	Q04759	PRKCQ	Q04759	PRKCQ	S676	E671K	671	Missense	distal	-5	no	2.038	2.249	EPSD	COSMIC	1.204	Up-regulation
AGC_PKC_PKCd_PRKCQ_ST	Q04759	PRKCQ	Q04759	PRKCQ	S676	K672N	672	Missense	distal	-4	no	2.038	2.011	EPSD	COSMIC	1.204	Down-regulation
AGC_PKC_PKCd_PRKCQ_ST	Q04759	PRKCQ	Q04759	PRKCQ	S676	D679H	679	Missense	distal	3	no	2.038	2.043	EPSD	COSMIC	1.204	Up-regulation
AGC_PKC_PKCd_PRKCQ_ST	Q04759	PRKCQ	Q04759	PRKCQ	S695	P699L	699	Missense	distal	4	no	1.753	1.708	EPSD	COSMIC	1.204	Down-regulation
AGC_PKC_PKCd_PRKCQ_ST	Q04759	PRKCQ	Q04759	PRKCQ	S695	N693S	693	Missense	proximal	-2	no	1.753	1.805	EPSD	COSMIC	1.204	Up-regulation
AGC_PKC_PKCd_PRKCQ_ST	Q04759	PRKCQ	Q04759	PRKCQ	S706	P699L	699	Missense	distal	-7	no	1.770	1.778	EPSD	COSMIC	1.204	Up-regulation
AGC_PKC_PKCd_PRKCQ_ST	P35568	IRS1	Q04759	PRKCQ	S24	K27R	27	Missense	distal	3	no	1.549	1.558	EPSD	COSMIC	1.204	Up-regulation
AGC_PKC_PKCd_PRKCQ_ST	P35568	IRS1	Q04759	PRKCQ	S24	V31I	31	Missense	distal	7	no	1.549	1.537	EPSD	COSMIC	1.204	Down-regulation
AGC_PKC_PKCd_PRKCQ_ST	P35568	IRS1	Q04759	PRKCQ	S24	G17C	17	Missense	distal	-7	no	1.549	1.548	EPSD	COSMIC	1.204	Down-regulation
AGC_PKC_PKCd_PRKCQ_ST	P35568	IRS1	Q04759	PRKCQ	S36	G40V	40	Missense	distal	4	no	1.488	1.476	EPSD	COSMIC	1.204	Down-regulation
AGC_PKC_PKCd_PRKCQ_ST	P35568	IRS1	Q04759	PRKCQ	S36	G39R	39	Missense	distal	3	no	1.488	1.511	EPSD	COSMIC	1.204	Up-regulation
AGC_PKC_PKCd_PRKCQ_ST	P35568	IRS1	Q04759	PRKCQ	S36	A34S	34	Missense	proximal	-2	no	1.488	1.553	EPSD	COSMIC	1.204	Up-regulation
AGC_PKC_PKCd_PRKCQ_ST	P35568	IRS1	Q04759	PRKCQ	S36	V31I	31	Missense	distal	-5	no	1.488	1.516	EPSD	COSMIC	1.204	Up-regulation
AGC_PKC_PKCd_PRKCQ_ST	P35568	IRS1	Q04759	PRKCQ	S193	K190N	190	Missense	distal	-3	no	1.310	0.546	EPSD	COSMIC	1.204	Loss
AGC_PKC_PKCd_PRKCQ_ST	P35568	IRS1	Q04759	PRKCQ	S193	S189N	189	Missense	distal	-4	no	1.310	1.294	EPSD	COSMIC	1.204	Down-regulation
AGC_PKC_PKCd_PRKCQ_ST	P35568	IRS1	Q04759	PRKCQ	S268	R265C	265	Missense	distal	-3	no	1.946	0.647	EPSD	COSMIC	1.204	Loss
AGC_PKC_PKCd_PRKCQ_ST	P35568	IRS1	Q04759	PRKCQ	S268	S274P	274	Missense	distal	6	no	1.946	1.943	EPSD	COSMIC	1.204	Down-regulation
AGC_PKC_PKCd_PRKCQ_ST	P35568	IRS1	Q04759	PRKCQ	S270	R265C	265	Missense	distal	-5	no	2.580	2.319	EPSD	COSMIC	1.204	Down-regulation
AGC_PKC_PKCd_PRKCQ_ST	P35568	IRS1	Q04759	PRKCQ	S270	S274P	274	Missense	distal	4	no	2.580	2.594	EPSD	COSMIC	1.204	Up-regulation
AGC_PKC_PKCd_PRKCQ_ST	P35568	IRS1	Q04759	PRKCQ	S272	R265C	265	Missense	distal	-7	no	1.399	1.422	EPSD	COSMIC	1.204	Up-regulation
AGC_PKC_PKCd_PRKCQ_ST	P35568	IRS1	Q04759	PRKCQ	S272	S274P	274	Missense	proximal	2	no	1.399	1.458	EPSD	COSMIC	1.204	Up-regulation
AGC_PKC_PKCd_PRKCQ_ST	P35568	IRS1	Q04759	PRKCQ	S303	A310T	310	Missense	distal	7	no	1.174	1.206	EPSD	COSMIC	1.204	Gain
AGC_PKC_PKCd_PRKCQ_ST	P35568	IRS1	Q04759	PRKCQ	S303	A310V	310	Missense	distal	7	no	1.174	1.215	EPSD	COSMIC	1.204	Gain
AGC_PKC_PKCd_PRKCQ_ST	P35568	IRS1	Q04759	PRKCQ	T305	R301C	301	Missense	distal	-4	no	1.234	1.176	EPSD	COSMIC	1.204	Loss
AGC_PKC_PKCd_PRKCQ_ST	P35568	IRS1	Q04759	PRKCQ	T305	E306K	306	Missense	proximal	1	no	1.234	1.244	EPSD	COSMIC	1.204	Up-regulation
AGC_PKC_PKCd_PRKCQ_ST	P35568	IRS1	Q04759	PRKCQ	T305	A310T	310	Missense	distal	5	no	1.234	1.227	EPSD	COSMIC	1.204	Down-regulation
AGC_PKC_PKCd_PRKCQ_ST	P35568	IRS1	Q04759	PRKCQ	T305	R302L	302	Missense	distal	-3	no	1.234	-0.115	EPSD	COSMIC	1.204	Loss
AGC_PKC_PKCd_PRKCQ_ST	P35568	IRS1	Q04759	PRKCQ	T305	I308M	308	Missense	distal	3	no	1.234	1.239	EPSD	COSMIC	1.204	Up-regulation
AGC_PKC_PKCd_PRKCQ_ST	P35568	IRS1	Q04759	PRKCQ	T305	A310V	310	Missense	distal	5	no	1.234	1.224	EPSD	COSMIC	1.204	Down-regulation
AGC_PKC_PKCd_PRKCQ_ST	P35568	IRS1	Q04759	PRKCQ	S307	R301C	301	Missense	distal	-6	no	1.791	2.030	EPSD	COSMIC	1.204	Up-regulation
AGC_PKC_PKCd_PRKCQ_ST	P35568	IRS1	Q04759	PRKCQ	S307	E306K	306	Missense	proximal	-1	no	1.791	1.798	EPSD	COSMIC	1.204	Up-regulation
AGC_PKC_PKCd_PRKCQ_ST	P35568	IRS1	Q04759	PRKCQ	S307	A310T	310	Missense	distal	3	no	1.791	1.784	EPSD	COSMIC	1.204	Down-regulation
AGC_PKC_PKCd_PRKCQ_ST	P35568	IRS1	Q04759	PRKCQ	S307	P313L	313	Missense	distal	6	no	1.791	1.774	EPSD	COSMIC;GDSC;CCLE	1.204	Down-regulation
AGC_PKC_PKCd_PRKCQ_ST	P35568	IRS1	Q04759	PRKCQ	S307	R302L	302	Missense	distal	-5	no	1.791	1.516	EPSD	COSMIC	1.204	Down-regulation
AGC_PKC_PKCd_PRKCQ_ST	P35568	IRS1	Q04759	PRKCQ	S307	I308M	308	Missense	proximal	1	no	1.791	1.794	EPSD	COSMIC	1.204	Up-regulation
AGC_PKC_PKCd_PRKCQ_ST	P35568	IRS1	Q04759	PRKCQ	S307	A310V	310	Missense	distal	3	no	1.791	1.782	EPSD	COSMIC	1.204	Down-regulation
AGC_PKC_PKCd_PRKCQ_ST	P35568	IRS1	Q04759	PRKCQ	S323	R327L	327	Missense	distal	4	no	1.628	1.450	EPSD	COSMIC	1.204	Down-regulation
AGC_PKC_PKCd_PRKCQ_ST	P35568	IRS1	Q04759	PRKCQ	S323	R325H	325	Missense	proximal	2	no	1.628	1.403	EPSD	COSMIC;CCLE	1.204	Down-regulation
AGC_PKC_PKCd_PRKCQ_ST	P35568	IRS1	Q04759	PRKCQ	S323	R327C	327	Missense	distal	4	no	1.628	1.453	EPSD	COSMIC;CCLE	1.204	Down-regulation
AGC_PKC_PKCd_PRKCQ_ST	P35568	IRS1	Q04759	PRKCQ	S323	M316V	316	Missense	distal	-7	no	1.628	1.636	EPSD	COSMIC	1.204	Up-regulation
AGC_PKC_PKCd_PRKCQ_ST	P35568	IRS1	Q04759	PRKCQ	S323	M316I	316	Missense	distal	-7	no	1.628	1.633	EPSD	COSMIC	1.204	Up-regulation
AGC_PKC_PKCd_PRKCQ_ST	P35568	IRS1	Q04759	PRKCQ	S323	R325C	325	Missense	proximal	2	no	1.628	1.364	EPSD	COSMIC	1.204	Down-regulation
AGC_PKC_PKCd_PRKCQ_ST	P35568	IRS1	Q04759	PRKCQ	S323	F324L	324	Missense	proximal	1	no	1.628	1.626	EPSD	COSMIC	1.204	Down-regulation
AGC_PKC_PKCd_PRKCQ_ST	P35568	IRS1	Q04759	PRKCQ	S330	R327L	327	Missense	distal	-3	no	1.440	0.090	EPSD	COSMIC	1.204	Loss
AGC_PKC_PKCd_PRKCQ_ST	P35568	IRS1	Q04759	PRKCQ	S330	R325H	325	Missense	distal	-5	no	1.440	1.219	EPSD	COSMIC;CCLE	1.204	Down-regulation
AGC_PKC_PKCd_PRKCQ_ST	P35568	IRS1	Q04759	PRKCQ	S330	R327C	327	Missense	distal	-3	no	1.440	0.140	EPSD	COSMIC;CCLE	1.204	Loss
AGC_PKC_PKCd_PRKCQ_ST	P35568	IRS1	Q04759	PRKCQ	S330	E333K	333	Missense	distal	3	no	1.440	1.454	EPSD	COSMIC	1.204	Up-regulation
AGC_PKC_PKCd_PRKCQ_ST	P35568	IRS1	Q04759	PRKCQ	S330	G332R	332	Missense	proximal	2	no	1.440	1.719	EPSD	COSMIC	1.204	Up-regulation
AGC_PKC_PKCd_PRKCQ_ST	P35568	IRS1	Q04759	PRKCQ	S330	R325C	325	Missense	distal	-5	no	1.440	1.178	EPSD	COSMIC	1.204	Loss
AGC_PKC_PKCd_PRKCQ_ST	P35568	IRS1	Q04759	PRKCQ	S330	F324L	324	Missense	distal	-6	no	1.440	1.484	EPSD	COSMIC	1.204	Up-regulation
AGC_PKC_PKCd_PRKCQ_ST	P35568	IRS1	Q04759	PRKCQ	S341	S341L	341	Missense	central	0	yes	2.052	0.000	EPSD	COSMIC	1.204	Loss
AGC_PKC_PKCd_PRKCQ_ST	P35568	IRS1	Q04759	PRKCQ	S341	P346S	346	Missense	distal	5	no	2.052	2.049	EPSD	COSMIC	1.204	Down-regulation
AGC_PKC_PKCd_PRKCQ_ST	P35568	IRS1	Q04759	PRKCQ	S362	L369F	369	Missense	distal	7	no	1.815	1.802	EPSD	COSMIC	1.204	Down-regulation
AGC_PKC_PKCd_PRKCQ_ST	P35568	IRS1	Q04759	PRKCQ	S362	A356P	356	Missense	distal	-6	no	1.815	1.794	EPSD	COSMIC	1.204	Down-regulation
AGC_PKC_PKCd_PRKCQ_ST	P35568	IRS1	Q04759	PRKCQ	S362	R364Q	364	Missense	proximal	2	no	1.815	1.578	EPSD	COSMIC	1.204	Down-regulation
AGC_PKC_PKCd_PRKCQ_ST	P35568	IRS1	Q04759	PRKCQ	S362	R358Q	358	Missense	distal	-4	no	1.815	1.768	EPSD	COSMIC	1.204	Down-regulation
AGC_PKC_PKCd_PRKCQ_ST	P35568	IRS1	Q04759	PRKCQ	S362	G361S	361	Missense	proximal	-1	no	1.815	1.819	EPSD	COSMIC	1.204	Up-regulation
AGC_PKC_PKCd_PRKCQ_ST	P35568	IRS1	Q04759	PRKCQ	S383	A379P	379	Missense	distal	-4	no	1.259	1.261	EPSD	COSMIC	1.204	Up-regulation
AGC_PKC_PKCd_PRKCQ_ST	P35568	IRS1	Q04759	PRKCQ	S383	S383L	383	Missense	central	0	yes	1.259	0.000	EPSD	COSMIC	1.204	Loss
AGC_PKC_PKCd_PRKCQ_ST	P35568	IRS1	Q04759	PRKCQ	S383	R381L	381	Missense	proximal	-2	no	1.259	0.508	EPSD	COSMIC	1.204	Loss
AGC_PKC_PKCd_PRKCQ_ST	P35568	IRS1	Q04759	PRKCQ	S383	S383W	383	Missense	central	0	yes	1.259	0.000	EPSD	COSMIC	1.204	Loss
AGC_PKC_PKCd_PRKCQ_ST	P35568	IRS1	Q04759	PRKCQ	S383	P384S	384	Missense	proximal	1	no	1.259	1.257	EPSD	COSMIC	1.204	Down-regulation
AGC_PKC_PKCd_PRKCQ_ST	P35568	IRS1	Q04759	PRKCQ	S383	S385L	385	Missense	proximal	2	no	1.259	1.236	EPSD	COSMIC	1.204	Down-regulation
AGC_PKC_PKCd_PRKCQ_ST	P35568	IRS1	Q04759	PRKCQ	S412	S415L	415	Missense	distal	3	no	1.494	1.485	EPSD	COSMIC	1.204	Down-regulation
AGC_PKC_PKCd_PRKCQ_ST	P35568	IRS1	Q04759	PRKCQ	S412	G418V	418	Missense	distal	6	no	1.494	1.489	EPSD	COSMIC;GDSC;CCLE	1.204	Down-regulation
AGC_PKC_PKCd_PRKCQ_ST	P35568	IRS1	Q04759	PRKCQ	S413	S415L	415	Missense	proximal	2	no	2.138	2.116	EPSD	COSMIC	1.204	Down-regulation
AGC_PKC_PKCd_PRKCQ_ST	P35568	IRS1	Q04759	PRKCQ	S413	G418V	418	Missense	distal	5	no	2.138	2.136	EPSD	COSMIC;GDSC;CCLE	1.204	Down-regulation
AGC_PKC_PKCd_PRKCQ_ST	P35568	IRS1	Q04759	PRKCQ	S441	P435L	435	Missense	distal	-6	no	1.831	1.905	EPSD	COSMIC	1.204	Up-regulation
AGC_PKC_PKCd_PRKCQ_ST	P35568	IRS1	Q04759	PRKCQ	S441	R439Q	439	Missense	proximal	-2	no	1.831	1.175	EPSD	COSMIC	1.204	Loss
AGC_PKC_PKCd_PRKCQ_ST	P35568	IRS1	Q04759	PRKCQ	S441	D448E	448	Missense	distal	7	no	1.831	1.826	EPSD	COSMIC	1.204	Down-regulation
AGC_PKC_PKCd_PRKCQ_ST	P35568	IRS1	Q04759	PRKCQ	S441	S441Y	441	Missense	central	0	yes	1.831	0.000	EPSD	COSMIC	1.204	Loss
AGC_PKC_PKCd_PRKCQ_ST	P35568	IRS1	Q04759	PRKCQ	S441	S434G	434	Missense	distal	-7	no	1.831	1.835	EPSD	COSMIC	1.204	Up-regulation
AGC_PKC_PKCd_PRKCQ_ST	P35568	IRS1	Q04759	PRKCQ	S441	S441F	441	Missense	central	0	yes	1.831	0.000	EPSD	COSMIC	1.204	Loss
AGC_PKC_PKCd_PRKCQ_ST	P35568	IRS1	Q04759	PRKCQ	S441	R443C	443	Missense	proximal	2	no	1.831	1.566	EPSD	COSMIC	1.204	Down-regulation
AGC_PKC_PKCd_PRKCQ_ST	P35568	IRS1	Q04759	PRKCQ	S441	P435F	435	Missense	distal	-6	no	1.831	1.861	EPSD	COSMIC	1.204	Up-regulation
AGC_PKC_PKCd_PRKCQ_ST	P35568	IRS1	Q04759	PRKCQ	S441	P447L	447	Missense	distal	6	no	1.831	1.814	EPSD	COSMIC	1.204	Down-regulation
AGC_PKC_PKCd_PRKCQ_ST	P35568	IRS1	Q04759	PRKCQ	S441	R443L	443	Missense	proximal	2	no	1.831	1.552	EPSD	COSMIC	1.204	Down-regulation
AGC_PKC_PKCd_PRKCQ_ST	P35568	IRS1	Q04759	PRKCQ	S441	S444I	444	Missense	distal	3	no	1.831	1.822	EPSD	COSMIC	1.204	Down-regulation
AGC_PKC_PKCd_PRKCQ_ST	P35568	IRS1	Q04759	PRKCQ	T525	T530A	530	Missense	distal	5	no	1.703	1.710	EPSD	COSMIC	1.204	Up-regulation
AGC_PKC_PKCd_PRKCQ_ST	P35568	IRS1	Q04759	PRKCQ	T525	R520L	520	Missense	distal	-5	no	1.703	1.428	EPSD	COSMIC	1.204	Down-regulation
AGC_PKC_PKCd_PRKCQ_ST	P35568	IRS1	Q04759	PRKCQ	T525	F521I	521	Missense	distal	-4	no	1.703	1.694	EPSD	COSMIC	1.204	Down-regulation
AGC_PKC_PKCd_PRKCQ_ST	P35568	IRS1	Q04759	PRKCQ	T525	H526Y	526	Missense	proximal	1	no	1.703	1.702	EPSD	COSMIC	1.204	Down-regulation
AGC_PKC_PKCd_PRKCQ_ST	P35568	IRS1	Q04759	PRKCQ	T525	G529D	529	Missense	distal	4	no	1.703	1.694	EPSD	COSMIC	1.204	Down-regulation
AGC_PKC_PKCd_PRKCQ_ST	P35568	IRS1	Q04759	PRKCQ	S527	T530A	530	Missense	distal	3	no	1.950	1.957	EPSD	COSMIC	1.204	Up-regulation
AGC_PKC_PKCd_PRKCQ_ST	P35568	IRS1	Q04759	PRKCQ	S527	R520L	520	Missense	distal	-7	no	1.950	1.975	EPSD	COSMIC	1.204	Up-regulation
AGC_PKC_PKCd_PRKCQ_ST	P35568	IRS1	Q04759	PRKCQ	S527	T533I	533	Missense	distal	6	no	1.950	1.956	EPSD	COSMIC	1.204	Up-regulation
AGC_PKC_PKCd_PRKCQ_ST	P35568	IRS1	Q04759	PRKCQ	S527	F521I	521	Missense	distal	-6	no	1.950	1.986	EPSD	COSMIC	1.204	Up-regulation
AGC_PKC_PKCd_PRKCQ_ST	P35568	IRS1	Q04759	PRKCQ	S527	H526Y	526	Missense	proximal	-1	no	1.950	1.949	EPSD	COSMIC	1.204	Down-regulation
AGC_PKC_PKCd_PRKCQ_ST	P35568	IRS1	Q04759	PRKCQ	S527	G529D	529	Missense	proximal	2	no	1.950	1.939	EPSD	COSMIC	1.204	Down-regulation
AGC_PKC_PKCd_PRKCQ_ST	P35568	IRS1	Q04759	PRKCQ	S574	P578S	578	Missense	distal	4	no	1.323	1.309	EPSD	COSMIC	1.204	Down-regulation
AGC_PKC_PKCd_PRKCQ_ST	P35568	IRS1	Q04759	PRKCQ	S574	F576L	576	Missense	proximal	2	no	1.323	1.269	EPSD	COSMIC	1.204	Down-regulation
AGC_PKC_PKCd_PRKCQ_ST	P35568	IRS1	Q04759	PRKCQ	S603	H598R	598	Missense	distal	-5	no	2.139	2.360	EPSD	COSMIC	1.204	Up-regulation
AGC_PKC_PKCd_PRKCQ_ST	P35568	IRS1	Q04759	PRKCQ	S603	G596E	596	Missense	distal	-7	no	2.139	2.140	EPSD	COSMIC	1.204	Up-regulation
AGC_PKC_PKCd_PRKCQ_ST	P35568	IRS1	Q04759	PRKCQ	S603	H599Y	599	Missense	distal	-4	no	2.139	2.134	EPSD	COSMIC	1.204	Down-regulation
AGC_PKC_PKCd_PRKCQ_ST	P35568	IRS1	Q04759	PRKCQ	S603	H599Q	599	Missense	distal	-4	no	2.139	2.141	EPSD	COSMIC	1.204	Up-regulation
AGC_PKC_PKCd_PRKCQ_ST	P35568	IRS1	Q04759	PRKCQ	S629	G628D	628	Missense	proximal	-1	no	2.138	2.137	EPSD	COSMIC	1.204	Down-regulation
AGC_PKC_PKCd_PRKCQ_ST	P35568	IRS1	Q04759	PRKCQ	S629	R626Q	626	Missense	distal	-3	no	2.138	0.910	EPSD	COSMIC	1.204	Loss
AGC_PKC_PKCd_PRKCQ_ST	P35568	IRS1	Q04759	PRKCQ	S629	V622M	622	Missense	distal	-7	no	2.138	2.130	EPSD	COSMIC	1.204	Down-regulation
AGC_PKC_PKCd_PRKCQ_ST	P35568	IRS1	Q04759	PRKCQ	S629	G630E	630	Missense	proximal	1	no	2.138	2.139	EPSD	COSMIC	1.204	Up-regulation
AGC_PKC_PKCd_PRKCQ_ST	P35568	IRS1	Q04759	PRKCQ	S641	V640I	640	Missense	proximal	-1	no	1.435	1.437	EPSD	COSMIC;GDSC;CCLE	1.204	Up-regulation
AGC_PKC_PKCd_PRKCQ_ST	P35568	IRS1	Q04759	PRKCQ	S641	A642T	642	Missense	proximal	1	no	1.435	1.431	EPSD	COSMIC	1.204	Down-regulation
AGC_PKC_PKCd_PRKCQ_ST	P35568	IRS1	Q04759	PRKCQ	S792	R785Q	785	Missense	distal	-7	no	1.315	1.336	EPSD	COSMIC	1.204	Up-regulation
AGC_PKC_PKCd_PRKCQ_ST	P35568	IRS1	Q04759	PRKCQ	S792	S792F	792	Missense	central	0	yes	1.315	0.000	EPSD	COSMIC	1.204	Loss
AGC_PKC_PKCd_PRKCQ_ST	P35568	IRS1	Q04759	PRKCQ	S792	R790C	790	Missense	proximal	-2	no	1.315	0.611	EPSD	COSMIC	1.204	Loss
AGC_PKC_PKCd_PRKCQ_ST	P35568	IRS1	Q04759	PRKCQ	S792	Q787R	787	Missense	distal	-5	no	1.315	1.550	EPSD	COSMIC	1.204	Up-regulation
AGC_PKC_PKCd_PRKCQ_ST	P35568	IRS1	Q04759	PRKCQ	S862	T859M	859	Missense	distal	-3	no	1.309	1.385	EPSD	COSMIC	1.204	Up-regulation
AGC_PKC_PKCd_PRKCQ_ST	P35568	IRS1	Q04759	PRKCQ	S862	L855P	855	Missense	distal	-7	no	1.309	1.302	EPSD	COSMIC	1.204	Down-regulation
AGC_PKC_PKCd_PRKCQ_ST	P35568	IRS1	Q04759	PRKCQ	S862	R857Q	857	Missense	distal	-5	no	1.309	1.073	EPSD	COSMIC	1.204	Loss
AGC_PKC_PKCd_PRKCQ_ST	P35568	IRS1	Q04759	PRKCQ	S862	G864W	864	Missense	proximal	2	no	1.309	1.324	EPSD	COSMIC	1.204	Up-regulation
AGC_PKC_PKCd_PRKCQ_ST	P35568	IRS1	Q04759	PRKCQ	S862	P858H	858	Missense	distal	-4	no	1.309	1.302	EPSD	COSMIC	1.204	Down-regulation
AGC_PKC_PKCd_PRKCQ_ST	P35568	IRS1	Q04759	PRKCQ	S869	G864W	864	Missense	distal	-5	no	1.781	1.788	EPSD	COSMIC	1.204	Up-regulation
AGC_PKC_PKCd_PRKCQ_ST	P35568	IRS1	Q04759	PRKCQ	S869	P872T	872	Missense	distal	3	no	1.781	1.774	EPSD	COSMIC	1.204	Down-regulation
AGC_PKC_PKCd_PRKCQ_ST	P35568	IRS1	Q04759	PRKCQ	S995	M992K	992	Missense	distal	-3	no	0.745	1.484	EPSD	COSMIC	1.204	Gain
AGC_PKC_PKCd_PRKCQ_ST	P35568	IRS1	Q04759	PRKCQ	S1000	R998C	998	Missense	proximal	-2	no	1.727	1.024	EPSD	COSMIC;GDSC;CCLE	1.204	Loss
AGC_PKC_PKCd_PRKCQ_ST	P35568	IRS1	Q04759	PRKCQ	S1000	D1003H	1003	Missense	distal	3	no	1.727	1.732	EPSD	COSMIC	1.204	Up-regulation
AGC_PKC_PKCd_PRKCQ_ST	P35568	IRS1	Q04759	PRKCQ	S1000	P997S	997	Missense	distal	-3	no	1.727	1.623	EPSD	COSMIC	1.204	Down-regulation
AGC_PKC_PKCd_PRKCQ_ST	P35568	IRS1	Q04759	PRKCQ	S1084	P1079S	1079	Missense	distal	-5	no	1.829	1.831	EPSD	COSMIC	1.204	Up-regulation
AGC_PKC_PKCd_PRKCQ_ST	P35568	IRS1	Q04759	PRKCQ	S1084	S1078I	1078	Missense	distal	-6	no	1.829	1.905	EPSD	COSMIC	1.204	Up-regulation
AGC_PKC_PKCd_PRKCQ_ST	P35568	IRS1	Q04759	PRKCQ	S1084	V1087A	1087	Missense	distal	3	no	1.829	1.837	EPSD	COSMIC	1.204	Up-regulation
AGC_PKC_PKCd_PRKCQ_ST	P35568	IRS1	Q04759	PRKCQ	S1084	R1081C	1081	Missense	distal	-3	no	1.829	0.529	EPSD	COSMIC	1.204	Loss
AGC_PKC_PKCd_PRKCQ_ST	P35568	IRS1	Q04759	PRKCQ	S1100	R1097W	1097	Missense	distal	-3	no	2.727	1.415	EPSD	COSMIC	1.204	Down-regulation
AGC_PKC_PKCd_PRKCQ_ST	P35568	IRS1	Q04759	PRKCQ	S1100	E1102K	1102	Missense	proximal	2	no	2.727	2.935	EPSD	COSMIC	1.204	Up-regulation
AGC_PKC_PKCd_PRKCQ_ST	P35568	IRS1	Q04759	PRKCQ	S1101	R1097W	1097	Missense	distal	-4	no	2.483	2.426	PhosphoSitePlus	COSMIC	1.204	Down-regulation
AGC_PKC_PKCd_PRKCQ_ST	P35568	IRS1	Q04759	PRKCQ	S1101	E1102K	1102	Missense	proximal	1	no	2.483	2.492	PhosphoSitePlus	COSMIC	1.204	Up-regulation
AGC_PKC_PKCd_PRKCQ_ST	P35568	IRS1	Q04759	PRKCQ	S1105	E1102K	1102	Missense	distal	-3	no	0.278	1.295	EPSD	COSMIC	1.204	Gain
AGC_PKC_PKCd_PRKCQ_ST	P35568	IRS1	Q04759	PRKCQ	S1142	R1140C	1140	Missense	proximal	-2	no	2.325	1.622	EPSD	COSMIC;CCLE	1.204	Down-regulation
AGC_PKC_PKCd_PRKCQ_ST	P35568	IRS1	Q04759	PRKCQ	S1143	R1140C	1140	Missense	distal	-3	no	2.131	0.831	EPSD	COSMIC;CCLE	1.204	Loss
AGC_PKC_PKCd_PRKCQ_ST	P35568	IRS1	Q04759	PRKCQ	S1222	R1220C	1220	Missense	proximal	-2	no	1.283	0.580	EPSD	COSMIC	1.204	Loss
AGC_PKC_PKCd_PRKCQ_ST	P35568	IRS1	Q04759	PRKCQ	S1222	D1225Y	1225	Missense	distal	3	no	1.283	1.286	EPSD	COSMIC	1.204	Up-regulation
AGC_PKC_PKCd_PRKCQ_ST	P35568	IRS1	Q04759	PRKCQ	S1222	A1228V	1228	Missense	distal	6	no	1.283	1.264	EPSD	COSMIC	1.204	Down-regulation
AGC_PKC_PKCd_PRKCQ_ST	P35568	IRS1	Q04759	PRKCQ	S1222	E1224Q	1224	Missense	proximal	2	no	1.283	1.337	EPSD	COSMIC	1.204	Up-regulation
AGC_PKC_PKCd_PRKCQ_ST	P35568	IRS1	Q04759	PRKCQ	S1222	L1226V	1226	Missense	distal	4	no	1.283	1.266	EPSD	COSMIC	1.204	Down-regulation
AGC_PKC_PKCd_PRKCQ_ST	P35568	IRS1	Q04759	PRKCQ	S1223	R1220C	1220	Missense	distal	-3	no	2.309	1.009	EPSD	COSMIC	1.204	Loss
AGC_PKC_PKCd_PRKCQ_ST	P35568	IRS1	Q04759	PRKCQ	S1223	D1225Y	1225	Missense	proximal	2	no	2.309	2.356	EPSD	COSMIC	1.204	Up-regulation
AGC_PKC_PKCd_PRKCQ_ST	P35568	IRS1	Q04759	PRKCQ	S1223	A1228V	1228	Missense	distal	5	no	2.309	2.298	EPSD	COSMIC	1.204	Down-regulation
AGC_PKC_PKCd_PRKCQ_ST	P35568	IRS1	Q04759	PRKCQ	S1223	E1224Q	1224	Missense	proximal	1	no	2.309	2.312	EPSD	COSMIC	1.204	Up-regulation
AGC_PKC_PKCd_PRKCQ_ST	P35568	IRS1	Q04759	PRKCQ	S1223	L1226V	1226	Missense	distal	3	no	2.309	2.306	EPSD	COSMIC	1.204	Down-regulation
AGC_PKC_PKCd_PRKCQ_ST	P35236	PTPN7	Q04759	PRKCQ	S44	L38F	38	Missense	distal	-6	no	2.732	2.688	EPSD;PhosphoSitePlus	COSMIC	1.204	Down-regulation
AGC_PKC_PKCd_PRKCQ_ST	P35236	PTPN7	Q04759	PRKCQ	S44	R42G	42	Missense	proximal	-2	no	2.732	2.010	EPSD;PhosphoSitePlus	COSMIC	1.204	Down-regulation
AGC_PKC_PKCd_PRKCQ_ST	P35236	PTPN7	Q04759	PRKCQ	S44	R42W	42	Missense	proximal	-2	no	2.732	2.018	EPSD;PhosphoSitePlus	COSMIC	1.204	Down-regulation
AGC_PKC_PKCd_PRKCQ_ST	P35236	PTPN7	Q04759	PRKCQ	S44	M49I	49	Missense	distal	5	no	2.732	2.726	EPSD;PhosphoSitePlus	COSMIC	1.204	Down-regulation
AGC_PKC_PKCd_PRKCQ_ST	P35236	PTPN7	Q04759	PRKCQ	S44	R41K	41	Missense	distal	-3	no	2.732	2.314	EPSD;PhosphoSitePlus	COSMIC	1.204	Down-regulation
AGC_PKC_PKCd_PRKCQ_ST	P35236	PTPN7	Q04759	PRKCQ	S44	A47D	47	Missense	distal	3	no	2.732	2.725	EPSD;PhosphoSitePlus	COSMIC	1.204	Down-regulation
AGC_PKC_PKCd_PRKCQ_ST	P35236	PTPN7	Q04759	PRKCQ	S106	F101L	101	Missense	distal	-5	no	1.445	1.391	EPSD	COSMIC	1.204	Down-regulation
AGC_PKC_PKCd_PRKCQ_ST	P35236	PTPN7	Q04759	PRKCQ	S106	F101I	101	Missense	distal	-5	no	1.445	1.400	EPSD	COSMIC	1.204	Down-regulation
AGC_PKC_PKCd_PRKCQ_ST	P35236	PTPN7	Q04759	PRKCQ	S106	E100Q	100	Missense	distal	-6	no	1.445	1.395	EPSD	COSMIC	1.204	Down-regulation
AGC_PKC_PKCd_PRKCQ_ST	Q3V6T2	CCDC88A	Q04759	PRKCQ	S230	P225L	225	Missense	distal	-5	no	1.221	1.138	EPSD	COSMIC	1.204	Loss
AGC_PKC_PKCd_PRKCQ_ST	Q3V6T2	CCDC88A	Q04759	PRKCQ	S230	S229C	229	Missense	proximal	-1	no	1.221	1.217	EPSD	COSMIC	1.204	Down-regulation
AGC_PKC_PKCd_PRKCQ_ST	Q3V6T2	CCDC88A	Q04759	PRKCQ	S230	S228T	228	Missense	proximal	-2	no	1.221	1.143	EPSD	COSMIC	1.204	Loss
AGC_PKC_PKCd_PRKCQ_ST	Q3V6T2	CCDC88A	Q04759	PRKCQ	S245	H248Y	248	Missense	distal	3	no	2.334	2.332	EPSD	COSMIC	1.204	Down-regulation
AGC_PKC_PKCd_PRKCQ_ST	Q3V6T2	CCDC88A	Q04759	PRKCQ	S245	S250L	250	Missense	distal	5	no	2.334	2.328	EPSD	COSMIC;GDSC;CCLE	1.204	Down-regulation
AGC_PKC_PKCd_PRKCQ_ST	Q3V6T2	CCDC88A	Q04759	PRKCQ	S245	R242Q	242	Missense	distal	-3	no	2.334	1.106	EPSD	COSMIC	1.204	Loss
AGC_PKC_PKCd_PRKCQ_ST	Q3V6T2	CCDC88A	Q04759	PRKCQ	S245	R246T	246	Missense	proximal	1	no	2.334	2.315	EPSD	COSMIC	1.204	Down-regulation
AGC_PKC_PKCd_PRKCQ_ST	Q3V6T2	CCDC88A	Q04759	PRKCQ	S1176	E1173K	1173	Missense	distal	-3	no	0.332	1.348	EPSD	COSMIC	1.204	Gain
AGC_PKC_PKCd_PRKCQ_ST	Q3V6T2	CCDC88A	Q04759	PRKCQ	S1417	R1414H	1414	Missense	distal	-3	no	1.768	0.655	EPSD	COSMIC	1.204	Loss
AGC_PKC_PKCd_PRKCQ_ST	Q3V6T2	CCDC88A	Q04759	PRKCQ	S1417	R1414C	1414	Missense	distal	-3	no	1.768	0.469	EPSD	COSMIC	1.204	Loss
AGC_PKC_PKCd_PRKCQ_ST	Q3V6T2	CCDC88A	Q04759	PRKCQ	S1417	R1412W	1412	Missense	distal	-5	no	1.768	1.507	EPSD	COSMIC	1.204	Down-regulation
AGC_PKC_PKCd_PRKCQ_ST	Q3V6T2	CCDC88A	Q04759	PRKCQ	S1417	R1412L	1412	Missense	distal	-5	no	1.768	1.493	EPSD	COSMIC	1.204	Down-regulation
AGC_PKC_PKCd_PRKCQ_ST	Q3V6T2	CCDC88A	Q04759	PRKCQ	S1427	F1431C	1431	Missense	distal	4	no	2.116	2.087	EPSD	COSMIC;CCLE	1.204	Down-regulation
AGC_PKC_PKCd_PRKCQ_ST	Q3V6T2	CCDC88A	Q04759	PRKCQ	S1462	K1459N	1459	Missense	distal	-3	no	1.420	0.657	EPSD	COSMIC	1.204	Loss
AGC_PKC_PKCd_PRKCQ_ST	Q3V6T2	CCDC88A	Q04759	PRKCQ	S1462	K1459Q	1459	Missense	distal	-3	no	1.420	0.610	EPSD	COSMIC	1.204	Loss
AGC_PKC_PKCd_PRKCQ_ST	Q3V6T2	CCDC88A	Q04759	PRKCQ	S1491	S1489F	1489	Missense	proximal	-2	no	1.838	1.845	EPSD	COSMIC	1.204	Up-regulation
AGC_PKC_PKCd_PRKCQ_ST	Q3V6T2	CCDC88A	Q04759	PRKCQ	S1491	R1487C	1487	Missense	distal	-4	no	1.838	1.779	EPSD	COSMIC;GDSC	1.204	Down-regulation
AGC_PKC_PKCd_PRKCQ_ST	Q3V6T2	CCDC88A	Q04759	PRKCQ	S1491	D1494N	1494	Missense	distal	3	no	1.838	1.842	EPSD	COSMIC;CCLE	1.204	Up-regulation
AGC_PKC_PKCd_PRKCQ_ST	Q3V6T2	CCDC88A	Q04759	PRKCQ	S1587	R1592T	1592	Missense	distal	5	no	1.968	1.939	EPSD	COSMIC	1.204	Down-regulation
AGC_PKC_PKCd_PRKCQ_ST	Q3V6T2	CCDC88A	Q04759	PRKCQ	S1587	V1580A	1580	Missense	distal	-7	no	1.968	1.961	EPSD	COSMIC	1.204	Down-regulation
AGC_PKC_PKCd_PRKCQ_ST	Q3V6T2	CCDC88A	Q04759	PRKCQ	S1587	A1586T	1586	Missense	proximal	-1	no	1.968	1.964	EPSD	COSMIC	1.204	Down-regulation
AGC_PKC_PKCd_PRKCQ_ST	Q3V6T2	CCDC88A	Q04759	PRKCQ	S1587	G1591A	1591	Missense	distal	4	no	1.968	2.003	EPSD	COSMIC	1.204	Up-regulation
AGC_PKC_PKCd_PRKCQ_ST	Q3V6T2	CCDC88A	Q04759	PRKCQ	S1594	G1591A	1591	Missense	distal	-3	no	1.161	1.251	EPSD	COSMIC	1.204	Gain
AGC_PKC_PKCd_PRKCQ_ST	Q3V6T2	CCDC88A	Q04759	PRKCQ	T1650	Q1644K	1644	Missense	distal	-6	no	1.311	1.210	EPSD	COSMIC	1.204	Down-regulation
AGC_PKC_PKCd_PRKCQ_ST	Q3V6T2	CCDC88A	Q04759	PRKCQ	T1650	R1651T	1651	Missense	proximal	1	no	1.311	1.293	EPSD	COSMIC	1.204	Down-regulation
AGC_PKC_PKCd_PRKCQ_ST	Q3V6T2	CCDC88A	Q04759	PRKCQ	T1650	Q1644R	1644	Missense	distal	-6	no	1.311	1.106	EPSD	COSMIC	1.204	Loss
AGC_PKC_PKCd_PRKCQ_ST	Q3V6T2	CCDC88A	Q04759	PRKCQ	T1650	L1656F	1656	Missense	distal	6	no	1.311	1.320	EPSD	COSMIC	1.204	Up-regulation
AGC_PKC_PKCd_PRKCQ_ST	Q3V6T2	CCDC88A	Q04759	PRKCQ	S1653	I1660M	1660	Missense	distal	7	no	1.580	1.555	EPSD	COSMIC	1.204	Down-regulation
AGC_PKC_PKCd_PRKCQ_ST	Q3V6T2	CCDC88A	Q04759	PRKCQ	S1653	R1651T	1651	Missense	proximal	-2	no	1.580	0.894	EPSD	COSMIC	1.204	Loss
AGC_PKC_PKCd_PRKCQ_ST	Q3V6T2	CCDC88A	Q04759	PRKCQ	S1653	L1656F	1656	Missense	distal	3	no	1.580	1.583	EPSD	COSMIC	1.204	Up-regulation
AGC_PKC_PKCd_PRKCQ_ST	Q3V6T2	CCDC88A	Q04759	PRKCQ	S1675	G1677E	1677	Missense	proximal	2	no	1.302	1.291	EPSD	COSMIC	1.204	Down-regulation
AGC_PKC_PKCd_PRKCQ_ST	Q3V6T2	CCDC88A	Q04759	PRKCQ	S1675	H1669Y	1669	Missense	distal	-6	no	1.302	1.320	EPSD	COSMIC	1.204	Up-regulation
AGC_PKC_PKCd_PRKCQ_ST	Q3V6T2	CCDC88A	Q04759	PRKCQ	S1675	H1669R	1669	Missense	distal	-6	no	1.302	1.097	EPSD	COSMIC	1.204	Loss
AGC_PKC_PKCd_PRKCQ_ST	Q3V6T2	CCDC88A	Q04759	PRKCQ	S1695	K1692R	1692	Missense	distal	-3	no	1.459	1.876	EPSD	COSMIC	1.204	Up-regulation
AGC_PKC_PKCd_PRKCQ_ST	Q3V6T2	CCDC88A	Q04759	PRKCQ	S1695	L1693F	1693	Missense	proximal	-2	no	1.459	1.608	EPSD	COSMIC	1.204	Up-regulation
AGC_PKC_PKCd_PRKCQ_ST	Q3V6T2	CCDC88A	Q04759	PRKCQ	S1702	D1708G	1708	Missense	distal	6	no	1.507	1.508	EPSD	COSMIC	1.204	Up-regulation
AGC_PKC_PKCd_PRKCQ_ST	Q3V6T2	CCDC88A	Q04759	PRKCQ	S1702	D1708H	1708	Missense	distal	6	no	1.507	1.518	EPSD	COSMIC	1.204	Up-regulation
AGC_PKC_PKCd_PRKCQ_ST	Q3V6T2	CCDC88A	Q04759	PRKCQ	S1715	D1708G	1708	Missense	distal	-7	no	1.492	1.491	EPSD	COSMIC	1.204	Down-regulation
AGC_PKC_PKCd_PRKCQ_ST	Q3V6T2	CCDC88A	Q04759	PRKCQ	S1715	D1708H	1708	Missense	distal	-7	no	1.492	1.486	EPSD	COSMIC	1.204	Down-regulation
AGC_PKC_PKCd_PRKCQ_ST	Q3V6T2	CCDC88A	Q04759	PRKCQ	S1728	V1735L	1735	Missense	distal	7	no	1.622	1.613	EPSD	COSMIC	1.204	Down-regulation
AGC_PKC_PKCd_PRKCQ_ST	Q3V6T2	CCDC88A	Q04759	PRKCQ	S1736	P1740S	1740	Missense	distal	4	no	1.991	1.977	EPSD	COSMIC	1.204	Down-regulation
AGC_PKC_PKCd_PRKCQ_ST	Q3V6T2	CCDC88A	Q04759	PRKCQ	S1736	V1735L	1735	Missense	proximal	-1	no	1.991	1.992	EPSD	COSMIC	1.204	Up-regulation
AGC_PKC_PKCd_PRKCQ_ST	Q3V6T2	CCDC88A	Q04759	PRKCQ	S1796	R1791K	1791	Missense	distal	-5	no	1.239	1.163	EPSD	COSMIC	1.204	Loss
AGC_PKC_PKCd_PRKCQ_ST	Q3V6T2	CCDC88A	Q04759	PRKCQ	S1796	P1803S	1803	Missense	distal	7	no	1.239	1.244	EPSD	COSMIC	1.204	Up-regulation
AGC_PKC_PKCd_PRKCQ_ST	Q3V6T2	CCDC88A	Q04759	PRKCQ	S1796	S1796C	1796	Missense	central	0	yes	1.239	0.000	EPSD	COSMIC	1.204	Loss
AGC_PKC_PKCd_PRKCQ_ST	Q3V6T2	CCDC88A	Q04759	PRKCQ	S1796	A1800E	1800	Missense	distal	4	no	1.239	1.201	EPSD	COSMIC	1.204	Loss
AGC_PKC_PKCd_PRKCQ_ST	Q3V6T2	CCDC88A	Q04759	PRKCQ	S1796	P1798L	1798	Missense	proximal	2	no	1.239	1.158	EPSD	COSMIC	1.204	Loss
AGC_PKC_PKCd_PRKCQ_ST	Q3V6T2	CCDC88A	Q04759	PRKCQ	S1806	A1812V	1812	Missense	distal	6	no	1.551	1.531	EPSD	COSMIC	1.204	Down-regulation
AGC_PKC_PKCd_PRKCQ_ST	Q3V6T2	CCDC88A	Q04759	PRKCQ	S1806	V1808M	1808	Missense	proximal	2	no	1.551	1.623	EPSD	COSMIC	1.204	Up-regulation
AGC_PKC_PKCd_PRKCQ_ST	Q3V6T2	CCDC88A	Q04759	PRKCQ	S1806	V1808L	1808	Missense	proximal	2	no	1.551	1.568	EPSD	COSMIC	1.204	Up-regulation
AGC_PKC_PKCd_PRKCQ_ST	Q3V6T2	CCDC88A	Q04759	PRKCQ	S1806	P1803S	1803	Missense	distal	-3	no	1.551	1.446	EPSD	COSMIC	1.204	Down-regulation
AGC_PKC_PKCd_PRKCQ_ST	Q3V6T2	CCDC88A	Q04759	PRKCQ	S1806	A1800E	1800	Missense	distal	-6	no	1.551	1.604	EPSD	COSMIC	1.204	Up-regulation
AGC_PKC_PKCd_PRKCQ_ST	Q3V6T2	CCDC88A	Q04759	PRKCQ	S1806	E1813K	1813	Missense	distal	7	no	1.551	1.502	EPSD	COSMIC	1.204	Down-regulation
AGC_PKC_PKCd_PRKCQ_ST	Q3V6T2	CCDC88A	Q04759	PRKCQ	S1806	R1804C	1804	Missense	proximal	-2	no	1.551	0.847	EPSD	COSMIC	1.204	Loss
AGC_PKC_PKCd_PRKCQ_ST	Q3V6T2	CCDC88A	Q04759	PRKCQ	S1807	A1812V	1812	Missense	distal	5	no	1.539	1.529	EPSD	COSMIC	1.204	Down-regulation
AGC_PKC_PKCd_PRKCQ_ST	Q3V6T2	CCDC88A	Q04759	PRKCQ	S1807	V1808M	1808	Missense	proximal	1	no	1.539	1.546	EPSD	COSMIC	1.204	Up-regulation
AGC_PKC_PKCd_PRKCQ_ST	Q3V6T2	CCDC88A	Q04759	PRKCQ	S1807	V1808L	1808	Missense	proximal	1	no	1.539	1.541	EPSD	COSMIC	1.204	Up-regulation
AGC_PKC_PKCd_PRKCQ_ST	Q3V6T2	CCDC88A	Q04759	PRKCQ	S1807	P1803S	1803	Missense	distal	-4	no	1.539	1.547	EPSD	COSMIC	1.204	Up-regulation
AGC_PKC_PKCd_PRKCQ_ST	Q3V6T2	CCDC88A	Q04759	PRKCQ	S1807	A1800E	1800	Missense	distal	-7	no	1.539	1.545	EPSD	COSMIC	1.204	Up-regulation
AGC_PKC_PKCd_PRKCQ_ST	Q3V6T2	CCDC88A	Q04759	PRKCQ	S1807	E1813K	1813	Missense	distal	6	no	1.539	1.577	EPSD	COSMIC	1.204	Up-regulation
AGC_PKC_PKCd_PRKCQ_ST	Q3V6T2	CCDC88A	Q04759	PRKCQ	S1807	R1804C	1804	Missense	distal	-3	no	1.539	0.240	EPSD	COSMIC	1.204	Loss
AGC_PKC_PKCd_PRKCQ_ST	Q3V6T2	CCDC88A	Q04759	PRKCQ	S1820	R1817K	1817	Missense	distal	-3	no	2.075	1.658	EPSD	COSMIC	1.204	Down-regulation
AGC_PKC_PKCd_PRKCQ_ST	Q3V6T2	CCDC88A	Q04759	PRKCQ	S1820	R1817Q	1817	Missense	distal	-3	no	2.075	0.847	EPSD	COSMIC	1.204	Loss
AGC_PKC_PKCd_PRKCQ_ST	Q3V6T2	CCDC88A	Q04759	PRKCQ	S1820	F1824S	1824	Missense	distal	4	no	2.075	2.076	EPSD	COSMIC	1.204	Up-regulation
AGC_PKC_PKCd_PRKCQ_ST	Q3V6T2	CCDC88A	Q04759	PRKCQ	S1820	E1813K	1813	Missense	distal	-7	no	2.075	2.058	EPSD	COSMIC	1.204	Down-regulation
AGC_PKC_PKCd_PRKCQ_ST	Q3V6T2	CCDC88A	Q04759	PRKCQ	S1820	T1815S	1815	Missense	distal	-5	no	2.075	2.149	EPSD	COSMIC	1.204	Up-regulation
AGC_PKC_PKCd_PRKCQ_ST	Q3V6T2	CCDC88A	Q04759	PRKCQ	S1820	R1818K	1818	Missense	proximal	-2	no	2.075	1.831	EPSD	COSMIC	1.204	Down-regulation
AGC_PKC_PKCd_PRKCQ_ST	Q3V6T2	CCDC88A	Q04759	PRKCQ	S1820	K1827N	1827	Missense	distal	7	no	2.075	2.112	EPSD	COSMIC	1.204	Up-regulation
AGC_PKC_PKCd_PRKCQ_ST	Q3V6T2	CCDC88A	Q04759	PRKCQ	S1820	L1825F	1825	Missense	distal	5	no	2.075	2.080	EPSD	COSMIC	1.204	Up-regulation
AGC_PKC_PKCd_PRKCQ_ST	O95267	RASGRP1	Q04759	PRKCQ	T184	L183V	183	Missense	proximal	-1	no	1.751	1.750	PhosphoSitePlus	COSMIC	1.204	Down-regulation
AGC_PKC_PKCd_PRKCQ_ST	O95267	RASGRP1	Q04759	PRKCQ	T184	R181M	181	Missense	distal	-3	no	1.751	0.594	PhosphoSitePlus	COSMIC	1.204	Loss
AGC_PKC_PKCd_PRKCQ_ST	O95267	RASGRP1	Q04759	PRKCQ	S198	E205K	205	Missense	distal	7	no	2.197	2.148	EPSD	COSMIC	1.204	Down-regulation
AGC_PKC_PKCd_PRKCQ_ST	O95267	RASGRP1	Q04759	PRKCQ	S661	R663Q	663	Missense	proximal	2	no	1.503	1.266	EPSD	COSMIC	1.204	Down-regulation
AGC_PKC_PKCd_PRKCQ_ST	O95267	RASGRP1	Q04759	PRKCQ	S661	L662F	662	Missense	proximal	1	no	1.503	1.506	EPSD	COSMIC	1.204	Up-regulation
AGC_PKC_PKCd_PRKCQ_ST	O95267	RASGRP1	Q04759	PRKCQ	S661	S661A	661	Missense	central	0	yes	1.503	0.000	EPSD	COSMIC;GDSC	1.204	Loss
AGC_PKC_PKCd_PRKCQ_ST	O95267	RASGRP1	Q04759	PRKCQ	S711	S708R	708	Missense	distal	-3	no	0.579	1.669	EPSD	COSMIC	1.204	Gain
AGC_PKC_PKCd_PRKCQ_ST	O95267	RASGRP1	Q04759	PRKCQ	S732	E738K	738	Missense	distal	6	no	1.220	1.258	EPSD	COSMIC	1.204	Up-regulation
AGC_PKC_PKCd_PRKCQ_ST	Q9BXL7	CARD11	Q04759	PRKCQ	S34	H31R	31	Missense	distal	-3	no	0.922	2.035	EPSD	COSMIC	1.204	Gain
AGC_PKC_PKCd_PRKCQ_ST	Q9BXL7	CARD11	Q04759	PRKCQ	S116	T112I	112	Missense	distal	-4	no	2.631	2.636	EPSD	COSMIC	1.204	Up-regulation
AGC_PKC_PKCd_PRKCQ_ST	Q9BXL7	CARD11	Q04759	PRKCQ	S116	G123D	123	Missense	distal	7	no	2.631	2.632	EPSD	COSMIC	1.204	Up-regulation
AGC_PKC_PKCd_PRKCQ_ST	Q9BXL7	CARD11	Q04759	PRKCQ	S116	S116P	116	Missense	central	0	yes	2.631	0.000	EPSD	COSMIC	1.204	Loss
AGC_PKC_PKCd_PRKCQ_ST	Q9BXL7	CARD11	Q04759	PRKCQ	S116	F115L	115	Missense	proximal	-1	no	2.631	2.629	EPSD	COSMIC	1.204	Down-regulation
AGC_PKC_PKCd_PRKCQ_ST	Q9BXL7	CARD11	Q04759	PRKCQ	S116	T117A	117	Missense	proximal	1	no	2.631	2.636	EPSD	COSMIC	1.204	Up-regulation
AGC_PKC_PKCd_PRKCQ_ST	Q9BXL7	CARD11	Q04759	PRKCQ	S116	R113Q	113	Missense	distal	-3	no	2.631	1.403	EPSD	COSMIC	1.204	Down-regulation
AGC_PKC_PKCd_PRKCQ_ST	Q9BXL7	CARD11	Q04759	PRKCQ	S116	F115S	115	Missense	proximal	-1	no	2.631	2.634	EPSD	COSMIC	1.204	Up-regulation
AGC_PKC_PKCd_PRKCQ_ST	Q9BXL7	CARD11	Q04759	PRKCQ	S116	R114K	114	Missense	proximal	-2	no	2.631	2.387	EPSD	COSMIC;GDSC;CCLE	1.204	Down-regulation
AGC_PKC_PKCd_PRKCQ_ST	Q9BXL7	CARD11	Q04759	PRKCQ	S116	G123C	123	Missense	distal	7	no	2.631	2.626	EPSD	COSMIC	1.204	Down-regulation
AGC_PKC_PKCd_PRKCQ_ST	Q9BXL7	CARD11	Q04759	PRKCQ	S439	E432K	432	Missense	distal	-7	no	2.329	2.312	EPSD	COSMIC	1.204	Down-regulation
AGC_PKC_PKCd_PRKCQ_ST	Q9BXL7	CARD11	Q04759	PRKCQ	S439	D441N	441	Missense	proximal	2	no	2.329	2.378	EPSD	COSMIC	1.204	Up-regulation
AGC_PKC_PKCd_PRKCQ_ST	Q9BXL7	CARD11	Q04759	PRKCQ	S439	N444K	444	Missense	distal	5	no	2.329	2.344	EPSD	COSMIC	1.204	Up-regulation
AGC_PKC_PKCd_PRKCQ_ST	Q9BXL7	CARD11	Q04759	PRKCQ	S439	R436W	436	Missense	distal	-3	no	2.329	1.017	EPSD	COSMIC	1.204	Loss
AGC_PKC_PKCd_PRKCQ_ST	Q9BXL7	CARD11	Q04759	PRKCQ	S439	R437C	437	Missense	proximal	-2	no	2.329	1.626	EPSD	COSMIC	1.204	Down-regulation
AGC_PKC_PKCd_PRKCQ_ST	Q9BXL7	CARD11	Q04759	PRKCQ	S439	R436Q	436	Missense	distal	-3	no	2.329	1.101	EPSD	COSMIC;GDSC;CCLE	1.204	Loss
AGC_PKC_PKCd_PRKCQ_ST	Q9BXL7	CARD11	Q04759	PRKCQ	S439	S439F	439	Missense	central	0	yes	2.329	0.000	EPSD	COSMIC	1.204	Loss
AGC_PKC_PKCd_PRKCQ_ST	Q9BXL7	CARD11	Q04759	PRKCQ	S512	R509I	509	Missense	distal	-3	no	1.722	0.410	EPSD	COSMIC	1.204	Loss
AGC_PKC_PKCd_PRKCQ_ST	Q9BXL7	CARD11	Q04759	PRKCQ	S512	P513F	513	Missense	proximal	1	no	1.722	1.720	EPSD	COSMIC	1.204	Down-regulation
AGC_PKC_PKCd_PRKCQ_ST	Q9BXL7	CARD11	Q04759	PRKCQ	S512	P513S	513	Missense	proximal	1	no	1.722	1.721	EPSD	COSMIC	1.204	Down-regulation
AGC_PKC_PKCd_PRKCQ_ST	Q9BXL7	CARD11	Q04759	PRKCQ	S512	S512F	512	Missense	central	0	yes	1.722	0.000	EPSD	COSMIC	1.204	Loss
AGC_PKC_PKCd_PRKCQ_ST	Q9BXL7	CARD11	Q04759	PRKCQ	S512	P513L	513	Missense	proximal	1	no	1.722	1.717	EPSD	COSMIC	1.204	Down-regulation
AGC_PKC_PKCd_PRKCQ_ST	Q9BXL7	CARD11	Q04759	PRKCQ	S512	P513H	513	Missense	proximal	1	no	1.722	1.720	EPSD	COSMIC	1.204	Down-regulation
AGC_PKC_PKCd_PRKCQ_ST	Q9BXL7	CARD11	Q04759	PRKCQ	S512	A510V	510	Missense	proximal	-2	no	1.722	1.605	EPSD	COSMIC;GDSC;CCLE	1.204	Down-regulation
AGC_PKC_PKCd_PRKCQ_ST	Q9BXL7	CARD11	Q04759	PRKCQ	S520	P513F	513	Missense	distal	-7	no	2.190	2.193	EPSD	COSMIC	1.204	Up-regulation
AGC_PKC_PKCd_PRKCQ_ST	Q9BXL7	CARD11	Q04759	PRKCQ	S520	A524S	524	Missense	distal	4	no	2.190	2.192	EPSD	COSMIC	1.204	Up-regulation
AGC_PKC_PKCd_PRKCQ_ST	Q9BXL7	CARD11	Q04759	PRKCQ	S520	P513S	513	Missense	distal	-7	no	2.190	2.193	EPSD	COSMIC	1.204	Up-regulation
AGC_PKC_PKCd_PRKCQ_ST	Q9BXL7	CARD11	Q04759	PRKCQ	S520	H527N	527	Missense	distal	7	no	2.190	2.192	EPSD	COSMIC;GDSC;CCLE	1.204	Up-regulation
AGC_PKC_PKCd_PRKCQ_ST	Q9BXL7	CARD11	Q04759	PRKCQ	S520	P513L	513	Missense	distal	-7	no	2.190	2.197	EPSD	COSMIC	1.204	Up-regulation
AGC_PKC_PKCd_PRKCQ_ST	Q9BXL7	CARD11	Q04759	PRKCQ	S520	K525R	525	Missense	distal	5	no	2.190	2.200	EPSD	COSMIC	1.204	Up-regulation
AGC_PKC_PKCd_PRKCQ_ST	Q9BXL7	CARD11	Q04759	PRKCQ	S520	P513H	513	Missense	distal	-7	no	2.190	2.192	EPSD	COSMIC	1.204	Up-regulation
AGC_PKC_PKCd_PRKCQ_ST	Q9BXL7	CARD11	Q04759	PRKCQ	S520	A524T	524	Missense	distal	4	no	2.190	2.166	EPSD	COSMIC	1.204	Down-regulation
AGC_PKC_PKCd_PRKCQ_ST	Q9BXL7	CARD11	Q04759	PRKCQ	S520	H527R	527	Missense	distal	7	no	2.190	2.097	EPSD	COSMIC	1.204	Down-regulation
AGC_PKC_PKCd_PRKCQ_ST	Q9BXL7	CARD11	Q04759	PRKCQ	S538	G540R	540	Missense	proximal	2	no	1.039	1.319	EPSD	COSMIC;GDSC	1.204	Gain
AGC_PKC_PKCd_PRKCQ_ST	Q9BXL7	CARD11	Q04759	PRKCQ	S558	R557S	557	Missense	proximal	-1	no	2.001	1.993	EPSD	COSMIC	1.204	Down-regulation
AGC_PKC_PKCd_PRKCQ_ST	Q9BXL7	CARD11	Q04759	PRKCQ	S558	P554S	554	Missense	distal	-4	no	2.001	2.008	EPSD	COSMIC	1.204	Up-regulation
AGC_PKC_PKCd_PRKCQ_ST	Q9BXL7	CARD11	Q04759	PRKCQ	S558	A565V	565	Missense	distal	7	no	2.001	2.041	EPSD	COSMIC	1.204	Up-regulation
AGC_PKC_PKCd_PRKCQ_ST	Q9BXL7	CARD11	Q04759	PRKCQ	S558	P553T	553	Missense	distal	-5	no	2.001	1.929	EPSD	COSMIC	1.204	Down-regulation
AGC_PKC_PKCd_PRKCQ_ST	Q9BXL7	CARD11	Q04759	PRKCQ	S558	A565T	565	Missense	distal	7	no	2.001	2.033	EPSD	COSMIC	1.204	Up-regulation
AGC_PKC_PKCd_PRKCQ_ST	Q9BXL7	CARD11	Q04759	PRKCQ	S558	S559C	559	Missense	proximal	1	no	2.001	1.998	EPSD	COSMIC	1.204	Down-regulation
AGC_PKC_PKCd_PRKCQ_ST	Q9BXL7	CARD11	Q04759	PRKCQ	S559	R557S	557	Missense	proximal	-2	no	1.890	1.282	PhosphoSitePlus	COSMIC	1.204	Down-regulation
AGC_PKC_PKCd_PRKCQ_ST	Q9BXL7	CARD11	Q04759	PRKCQ	S559	P554S	554	Missense	distal	-5	no	1.890	1.892	PhosphoSitePlus	COSMIC	1.204	Up-regulation
AGC_PKC_PKCd_PRKCQ_ST	Q9BXL7	CARD11	Q04759	PRKCQ	S559	A565V	565	Missense	distal	6	no	1.890	1.871	PhosphoSitePlus	COSMIC	1.204	Down-regulation
AGC_PKC_PKCd_PRKCQ_ST	Q9BXL7	CARD11	Q04759	PRKCQ	S559	E566K	566	Missense	distal	7	no	1.890	1.841	PhosphoSitePlus	COSMIC	1.204	Down-regulation
AGC_PKC_PKCd_PRKCQ_ST	Q9BXL7	CARD11	Q04759	PRKCQ	S559	P553T	553	Missense	distal	-6	no	1.890	1.959	PhosphoSitePlus	COSMIC	1.204	Up-regulation
AGC_PKC_PKCd_PRKCQ_ST	Q9BXL7	CARD11	Q04759	PRKCQ	S559	A565T	565	Missense	distal	6	no	1.890	1.871	PhosphoSitePlus	COSMIC	1.204	Down-regulation
AGC_PKC_PKCd_PRKCQ_ST	Q9BXL7	CARD11	Q04759	PRKCQ	S559	S559C	559	Missense	central	0	yes	1.890	0.000	PhosphoSitePlus	COSMIC	1.204	Loss
AGC_PKC_PKCd_PRKCQ_ST	Q9BXL7	CARD11	Q04759	PRKCQ	S562	E566K	566	Missense	distal	4	no	1.116	1.239	EPSD	COSMIC	1.204	Gain
AGC_PKC_PKCd_PRKCQ_ST	Q9BXL7	CARD11	Q04759	PRKCQ	S644	L645P	645	Missense	proximal	1	no	2.782	2.787	EPSD	COSMIC	1.204	Up-regulation
AGC_PKC_PKCd_PRKCQ_ST	Q9BXL7	CARD11	Q04759	PRKCQ	S644	L645Q	645	Missense	proximal	1	no	2.782	2.786	EPSD	COSMIC	1.204	Up-regulation
AGC_PKC_PKCd_PRKCQ_ST	Q9BXL7	CARD11	Q04759	PRKCQ	S644	F649S	649	Missense	distal	5	no	2.782	2.784	EPSD	COSMIC	1.204	Up-regulation
AGC_PKC_PKCd_PRKCQ_ST	Q9BXL7	CARD11	Q04759	PRKCQ	S644	M639V	639	Missense	distal	-5	no	2.782	2.709	EPSD	COSMIC	1.204	Down-regulation
AGC_PKC_PKCd_PRKCQ_ST	Q9BXL7	CARD11	Q04759	PRKCQ	S644	R647S	647	Missense	distal	3	no	2.782	2.769	EPSD	COSMIC	1.204	Down-regulation
AGC_PKC_PKCd_PRKCQ_ST	Q9BXL7	CARD11	Q04759	PRKCQ	S652	T654I	654	Missense	proximal	2	no	1.778	1.773	EPSD	COSMIC	1.204	Down-regulation
AGC_PKC_PKCd_PRKCQ_ST	Q9BXL7	CARD11	Q04759	PRKCQ	S652	L645P	645	Missense	distal	-7	no	1.778	1.771	EPSD	COSMIC	1.204	Down-regulation
AGC_PKC_PKCd_PRKCQ_ST	Q9BXL7	CARD11	Q04759	PRKCQ	S652	L645Q	645	Missense	distal	-7	no	1.778	1.774	EPSD	COSMIC	1.204	Down-regulation
AGC_PKC_PKCd_PRKCQ_ST	Q9BXL7	CARD11	Q04759	PRKCQ	S652	F649S	649	Missense	distal	-3	no	1.778	1.750	EPSD	COSMIC	1.204	Down-regulation
AGC_PKC_PKCd_PRKCQ_ST	Q9BXL7	CARD11	Q04759	PRKCQ	S652	R647S	647	Missense	distal	-5	no	1.778	1.588	EPSD	COSMIC	1.204	Down-regulation
AGC_PKC_PKCd_PRKCQ_ST	Q9BXL7	CARD11	Q04759	PRKCQ	S886	R888H	888	Missense	proximal	2	no	1.869	1.644	EPSD	COSMIC	1.204	Down-regulation
AGC_PKC_PKCd_PRKCQ_ST	Q9BXL7	CARD11	Q04759	PRKCQ	S886	S879L	879	Missense	distal	-7	no	1.869	1.874	EPSD	COSMIC	1.204	Up-regulation
AGC_PKC_PKCd_PRKCQ_ST	Q9BXL7	CARD11	Q04759	PRKCQ	S886	A892E	892	Missense	distal	6	no	1.869	1.855	EPSD	COSMIC	1.204	Down-regulation
AGC_PKC_PKCd_PRKCQ_ST	Q9BXL7	CARD11	Q04759	PRKCQ	S886	R891Q	891	Missense	distal	5	no	1.869	1.845	EPSD	COSMIC	1.204	Down-regulation
AGC_PKC_PKCd_PRKCQ_ST	Q9BXL7	CARD11	Q04759	PRKCQ	S886	V885I	885	Missense	proximal	-1	no	1.869	1.871	EPSD	COSMIC	1.204	Up-regulation
AGC_PKC_PKCd_PRKCQ_ST	Q9BXL7	CARD11	Q04759	PRKCQ	S886	R891L	891	Missense	distal	5	no	1.869	1.840	EPSD	COSMIC;CCLE	1.204	Down-regulation
AGC_PKC_PKCd_PRKCQ_ST	Q9BXL7	CARD11	Q04759	PRKCQ	S886	S893C	893	Missense	distal	7	no	1.869	1.886	EPSD	COSMIC	1.204	Up-regulation
AGC_PKC_PKCd_PRKCQ_ST	Q9BXL7	CARD11	Q04759	PRKCQ	S886	S890L	890	Missense	distal	4	no	1.869	1.838	EPSD	COSMIC	1.204	Down-regulation
AGC_PKC_PKCd_PRKCQ_ST	Q9BXL7	CARD11	Q04759	PRKCQ	S886	S893N	893	Missense	distal	7	no	1.869	1.875	EPSD	COSMIC	1.204	Up-regulation
AGC_PKC_PKCd_PRKCQ_ST	Q9BXL7	CARD11	Q04759	PRKCQ	S886	R884L	884	Missense	proximal	-2	no	1.869	1.119	EPSD	COSMIC	1.204	Loss
AGC_PKC_PKCd_PRKCQ_ST	Q9BXL7	CARD11	Q04759	PRKCQ	S923	P926S	926	Missense	distal	3	no	2.375	2.378	EPSD	COSMIC	1.204	Up-regulation
AGC_PKC_PKCd_PRKCQ_ST	Q9BXL7	CARD11	Q04759	PRKCQ	S923	S929R	929	Missense	distal	6	no	2.375	2.406	EPSD	COSMIC	1.204	Up-regulation
AGC_PKC_PKCd_PRKCQ_ST	Q9BXL7	CARD11	Q04759	PRKCQ	S923	R920C	920	Missense	distal	-3	no	2.375	1.076	EPSD	COSMIC	1.204	Loss
AGC_PKC_PKCd_PRKCQ_ST	Q9BXL7	CARD11	Q04759	PRKCQ	S923	S925N	925	Missense	proximal	2	no	2.375	2.389	EPSD	COSMIC	1.204	Up-regulation
AGC_PKC_PKCd_PRKCQ_ST	Q9BXL7	CARD11	Q04759	PRKCQ	S923	R918Q	918	Missense	distal	-5	no	2.375	2.139	EPSD	COSMIC	1.204	Down-regulation
AGC_PKC_PKCd_PRKCQ_ST	P10588	NR2F6	Q04759	PRKCQ	S83	N87K	87	Missense	distal	4	no	1.324	1.416	PhosphoSitePlus	COSMIC	1.204	Up-regulation
AGC_PKC_PKCd_PRKCQ_ST	P10588	NR2F6	Q04759	PRKCQ	S83	L88F	88	Missense	distal	5	no	1.324	1.328	PhosphoSitePlus	COSMIC;CCLE	1.204	Up-regulation
AGC_PKC_PKCd_PRKCQ_ST	P10588	NR2F6	Q04759	PRKCQ	S83	S78C	78	Missense	distal	-5	no	1.324	1.253	PhosphoSitePlus	COSMIC	1.204	Down-regulation
AGC_PKC_PKCd_PRKCQ_ST	P10588	NR2F6	Q04759	PRKCQ	S89	N87K	87	Missense	proximal	-2	no	2.271	2.688	EPSD	COSMIC	1.204	Up-regulation
AGC_PKC_PKCd_PRKCQ_ST	P10588	NR2F6	Q04759	PRKCQ	S89	L88F	88	Missense	proximal	-1	no	2.271	2.273	EPSD	COSMIC;CCLE	1.204	Up-regulation
AGC_PKC_PKCd_PRKCQ_ST	P01116	KRAS	Q04759	PRKCQ	S172	K169N	169	Missense	distal	-3	no	2.221	1.457	EPSD	COSMIC	1.204	Down-regulation
AGC_PKC_PKCd_PRKCQ_ST	P01116	KRAS	Q04759	PRKCQ	S172	G179S	179	Missense	distal	7	no	2.221	2.198	EPSD	COSMIC	1.204	Down-regulation
AGC_PKC_PKCd_PRKCQ_ST	P01116	KRAS	Q04759	PRKCQ	S172	K170Q	170	Missense	proximal	-2	no	2.221	1.808	EPSD	COSMIC	1.204	Down-regulation
AGC_PKC_PKCd_PRKCQ_ST	P01116	KRAS	Q04759	PRKCQ	S172	G179V	179	Missense	distal	7	no	2.221	2.229	EPSD	COSMIC	1.204	Up-regulation
AGC_PKC_PKCd_PRKCQ_ST	P01116	KRAS	Q04759	PRKCQ	S172	K176T	176	Missense	distal	4	no	2.221	2.112	EPSD	COSMIC	1.204	Down-regulation
AGC_PKC_PKCd_PRKCQ_ST	P15407	FOSL1	Q04759	PRKCQ	S251	D257H	257	Missense	distal	6	no	1.542	1.553	EPSD	COSMIC	1.204	Up-regulation
AGC_PKC_PKCd_PRKCQ_ST	P15407	FOSL1	Q04759	PRKCQ	S251	G256E	256	Missense	distal	5	no	1.542	1.543	EPSD	COSMIC	1.204	Up-regulation
AGC_PKC_PKCd_PRKCQ_ST	P15407	FOSL1	Q04759	PRKCQ	S251	C244F	244	Missense	distal	-7	no	1.542	1.539	EPSD	COSMIC	1.204	Down-regulation
AGC_PKC_PKCd_PRKCQ_ST	P15407	FOSL1	Q04759	PRKCQ	S252	D257H	257	Missense	distal	5	no	2.235	2.242	EPSD	COSMIC	1.204	Up-regulation
AGC_PKC_PKCd_PRKCQ_ST	P15407	FOSL1	Q04759	PRKCQ	S252	G256E	256	Missense	distal	4	no	2.235	2.232	EPSD	COSMIC	1.204	Down-regulation
AGC_PKC_PKCd_PRKCQ_ST	P15407	FOSL1	Q04759	PRKCQ	S253	D257H	257	Missense	distal	4	no	1.518	1.561	EPSD	COSMIC	1.204	Up-regulation
AGC_PKC_PKCd_PRKCQ_ST	P26038	MSN	Q04759	PRKCQ	S6	R8P	8	Missense	proximal	2	no	1.727	1.530	EPSD	COSMIC	1.204	Down-regulation
AGC_PKC_PKCd_PRKCQ_ST	P26038	MSN	Q04759	PRKCQ	S6	S6I	6	Missense	central	0	yes	1.727	0.000	EPSD	COSMIC	1.204	Loss
AGC_PKC_PKCd_PRKCQ_ST	P26038	MSN	Q04759	PRKCQ	S74	F80L	80	Missense	distal	6	no	2.000	1.992	EPSD	COSMIC	1.204	Down-regulation
AGC_PKC_PKCd_PRKCQ_ST	P26038	MSN	Q04759	PRKCQ	S74	R71W	71	Missense	distal	-3	no	2.000	0.688	EPSD	COSMIC	1.204	Loss
AGC_PKC_PKCd_PRKCQ_ST	P26038	MSN	Q04759	PRKCQ	S214	S214L	214	Missense	central	0	yes	2.190	0.000	EPSD	COSMIC	1.204	Loss
AGC_PKC_PKCd_PRKCQ_ST	P26038	MSN	Q04759	PRKCQ	S214	G219W	219	Missense	distal	5	no	2.190	2.193	EPSD	COSMIC	1.204	Up-regulation
AGC_PKC_PKCd_PRKCQ_ST	P26038	MSN	Q04759	PRKCQ	S249	S249C	249	Missense	central	0	yes	1.577	0.000	EPSD	COSMIC	1.204	Loss
AGC_PKC_PKCd_PRKCQ_ST	P26038	MSN	Q04759	PRKCQ	S249	F255C	255	Missense	distal	6	no	1.577	1.571	EPSD	COSMIC	1.204	Down-regulation
AGC_PKC_PKCd_PRKCQ_ST	P26038	MSN	Q04759	PRKCQ	S249	K254N	254	Missense	distal	5	no	1.577	1.563	EPSD	COSMIC	1.204	Down-regulation
AGC_PKC_PKCd_PRKCQ_ST	P26038	MSN	Q04759	PRKCQ	S384	K380R	380	Missense	distal	-4	no	2.355	2.380	EPSD	COSMIC	1.204	Up-regulation
AGC_PKC_PKCd_PRKCQ_ST	P26038	MSN	Q04759	PRKCQ	S504	A498V	498	Missense	distal	-6	no	1.474	1.544	EPSD	COSMIC	1.204	Up-regulation
AGC_PKC_PKCd_PRKCQ_ST	P26038	MSN	Q04759	PRKCQ	S504	R508H	508	Missense	distal	4	no	1.474	1.324	EPSD	COSMIC	1.204	Down-regulation
AGC_PKC_PKCd_PRKCQ_ST	P26038	MSN	Q04759	PRKCQ	S536	L529Q	529	Missense	distal	-7	no	1.722	1.718	EPSD	COSMIC	1.204	Down-regulation
AGC_PKC_PKCd_PRKCQ_ST	P26038	MSN	Q04759	PRKCQ	T558	R560H	560	Missense	proximal	2	no	1.471	1.245	PhosphoSitePlus	COSMIC;GDSC;CCLE	1.204	Down-regulation
AGC_PKC_PKCd_PRKCQ_ST	P26038	MSN	Q04759	PRKCQ	T558	K555R	555	Missense	distal	-3	no	1.471	1.888	PhosphoSitePlus	COSMIC	1.204	Up-regulation
AGC_PKC_PKCd_PRKCQ_ST	O43516	WIPF1	Q04759	PRKCQ	S135	G132R	132	Missense	distal	-3	no	0.589	1.907	EPSD	COSMIC;GDSC;CCLE	1.204	Gain
AGC_PKC_PKCd_PRKCQ_ST	O43516	WIPF1	Q04759	PRKCQ	S137	G132R	132	Missense	distal	-5	no	2.250	2.519	EPSD	COSMIC;GDSC;CCLE	1.204	Up-regulation
AGC_PKC_PKCd_PRKCQ_ST	O43516	WIPF1	Q04759	PRKCQ	S214	P220L	220	Missense	distal	6	no	1.518	1.501	EPSD	COSMIC	1.204	Down-regulation
AGC_PKC_PKCd_PRKCQ_ST	O43516	WIPF1	Q04759	PRKCQ	S276	N273K	273	Missense	distal	-3	no	1.112	1.875	EPSD	COSMIC	1.204	Gain
AGC_PKC_PKCd_PRKCQ_ST	O43516	WIPF1	Q04759	PRKCQ	S301	V294M	294	Missense	distal	-7	no	1.451	1.443	EPSD	COSMIC	1.204	Down-regulation
AGC_PKC_PKCd_PRKCQ_ST	O43516	WIPF1	Q04759	PRKCQ	S301	R299Q	299	Missense	proximal	-2	no	1.451	0.794	EPSD	COSMIC	1.204	Loss
AGC_PKC_PKCd_PRKCQ_ST	O43516	WIPF1	Q04759	PRKCQ	S340	P347T	347	Missense	distal	7	no	1.634	1.661	EPSD	COSMIC	1.204	Up-regulation
AGC_PKC_PKCd_PRKCQ_ST	O43516	WIPF1	Q04759	PRKCQ	S340	P346L	346	Missense	distal	6	no	1.634	1.617	EPSD	COSMIC	1.204	Down-regulation
AGC_PKC_PKCd_PRKCQ_ST	O43516	WIPF1	Q04759	PRKCQ	S340	S344F	344	Missense	distal	4	no	1.634	1.633	EPSD	COSMIC	1.204	Down-regulation
AGC_PKC_PKCd_PRKCQ_ST	O43516	WIPF1	Q04759	PRKCQ	S340	S344P	344	Missense	distal	4	no	1.634	1.648	EPSD	COSMIC;GDSC;CCLE	1.204	Up-regulation
AGC_PKC_PKCd_PRKCQ_ST	O43516	WIPF1	Q04759	PRKCQ	S390	G389D	389	Missense	proximal	-1	no	1.714	1.713	EPSD	COSMIC;CCLE	1.204	Down-regulation
AGC_PKC_PKCd_PRKCQ_ST	O43516	WIPF1	Q04759	PRKCQ	S424	R422K	422	Missense	proximal	-2	no	1.282	1.038	EPSD	COSMIC	1.204	Loss
AGC_PKC_PKCd_PRKCQ_ST	O43516	WIPF1	Q04759	PRKCQ	S434	T435P	435	Missense	proximal	1	no	1.313	1.316	EPSD	COSMIC	1.204	Up-regulation
AGC_PKC_PKCd_PRKCQ_ST	O43516	WIPF1	Q04759	PRKCQ	S434	P432S	432	Missense	proximal	-2	no	1.313	1.240	EPSD	COSMIC	1.204	Down-regulation
AGC_PKC_PKCd_PRKCQ_ST	O43516	WIPF1	Q04759	PRKCQ	S434	G440S	440	Missense	distal	6	no	1.313	1.333	EPSD	COSMIC	1.204	Up-regulation
AGC_PKC_PKCd_PRKCQ_ST	O43516	WIPF1	Q04759	PRKCQ	S436	T435P	435	Missense	proximal	-1	no	1.374	1.378	EPSD	COSMIC	1.204	Up-regulation
AGC_PKC_PKCd_PRKCQ_ST	O43516	WIPF1	Q04759	PRKCQ	S436	P432S	432	Missense	distal	-4	no	1.374	1.382	EPSD	COSMIC	1.204	Up-regulation
AGC_PKC_PKCd_PRKCQ_ST	O43516	WIPF1	Q04759	PRKCQ	S436	G440S	440	Missense	distal	4	no	1.374	1.411	EPSD	COSMIC	1.204	Up-regulation
AGC_PKC_PKCd_PRKCQ_ST	O43516	WIPF1	Q04759	PRKCQ	S488	R485L	485	Missense	distal	-3	no	2.044	0.695	PhosphoSitePlus	COSMIC	1.204	Loss
AGC_PKC_PKCd_PRKCQ_ST	O43516	WIPF1	Q04759	PRKCQ	S488	R485Q	485	Missense	distal	-3	no	2.044	0.816	PhosphoSitePlus	COSMIC	1.204	Loss
AGC_PKC_PKCd_PRKCQ_ST	Q9Y4G8	RAPGEF2	Q04759	PRKCQ	S276	T275N	275	Missense	proximal	-1	no	1.646	1.649	EPSD	COSMIC	1.204	Up-regulation
AGC_PKC_PKCd_PRKCQ_ST	Q9Y4G8	RAPGEF2	Q04759	PRKCQ	S276	K273R	273	Missense	distal	-3	no	1.646	2.064	EPSD	COSMIC	1.204	Up-regulation
AGC_PKC_PKCd_PRKCQ_ST	Q9Y4G8	RAPGEF2	Q04759	PRKCQ	S478	S478L	478	Missense	central	0	yes	1.434	0.000	EPSD	COSMIC	1.204	Loss
AGC_PKC_PKCd_PRKCQ_ST	Q9Y4G8	RAPGEF2	Q04759	PRKCQ	S478	L477F	477	Missense	proximal	-1	no	1.434	1.436	EPSD	COSMIC	1.204	Up-regulation
AGC_PKC_PKCd_PRKCQ_ST	Q9Y4G8	RAPGEF2	Q04759	PRKCQ	S912	N914S	914	Missense	proximal	2	no	1.529	1.515	EPSD	COSMIC	1.204	Down-regulation
AGC_PKC_PKCd_PRKCQ_ST	Q9Y4G8	RAPGEF2	Q04759	PRKCQ	S959	R958H	958	Missense	proximal	-1	no	1.710	1.699	EPSD	COSMIC	1.204	Down-regulation
AGC_PKC_PKCd_PRKCQ_ST	Q9Y4G8	RAPGEF2	Q04759	PRKCQ	S959	R958C	958	Missense	proximal	-1	no	1.710	1.698	EPSD	COSMIC	1.204	Down-regulation
AGC_PKC_PKCd_PRKCQ_ST	Q9Y4G8	RAPGEF2	Q04759	PRKCQ	S960	R958H	958	Missense	proximal	-2	no	2.930	2.328	PhosphoSitePlus	COSMIC	1.204	Down-regulation
AGC_PKC_PKCd_PRKCQ_ST	Q9Y4G8	RAPGEF2	Q04759	PRKCQ	S960	R958C	958	Missense	proximal	-2	no	2.930	2.227	PhosphoSitePlus	COSMIC	1.204	Down-regulation
AGC_PKC_PKCd_PRKCQ_ST	Q9Y4G8	RAPGEF2	Q04759	PRKCQ	S1089	K1086R	1086	Missense	distal	-3	no	1.308	1.725	EPSD	COSMIC	1.204	Up-regulation
AGC_PKC_PKCd_PRKCQ_ST	Q9Y4G8	RAPGEF2	Q04759	PRKCQ	S1089	L1096F	1096	Missense	distal	7	no	1.308	1.295	EPSD	COSMIC	1.204	Down-regulation
AGC_PKC_PKCd_PRKCQ_ST	Q9Y4G8	RAPGEF2	Q04759	PRKCQ	S1089	S1095F	1095	Missense	distal	6	no	1.308	1.296	EPSD	COSMIC	1.204	Down-regulation
AGC_PKC_PKCd_PRKCQ_ST	Q9Y4G8	RAPGEF2	Q04759	PRKCQ	S1153	R1151L	1151	Missense	proximal	-2	no	1.545	0.794	EPSD	COSMIC	1.204	Loss
AGC_PKC_PKCd_PRKCQ_ST	Q9Y4G8	RAPGEF2	Q04759	PRKCQ	S1153	S1159P	1159	Missense	distal	6	no	1.545	1.541	EPSD	COSMIC	1.204	Down-regulation
AGC_PKC_PKCd_PRKCQ_ST	Q9Y4G8	RAPGEF2	Q04759	PRKCQ	S1153	S1159Y	1159	Missense	distal	6	no	1.545	1.530	EPSD	COSMIC	1.204	Down-regulation
AGC_PKC_PKCd_PRKCQ_ST	Q9Y4G8	RAPGEF2	Q04759	PRKCQ	S1153	S1150C	1150	Missense	distal	-3	no	1.545	1.335	EPSD	COSMIC	1.204	Down-regulation
AGC_PKC_PKCd_PRKCQ_ST	Q9Y4G8	RAPGEF2	Q04759	PRKCQ	S1176	E1170K	1170	Missense	distal	-6	no	1.864	1.713	EPSD	COSMIC	1.204	Down-regulation
AGC_PKC_PKCd_PRKCQ_ST	Q9Y4G8	RAPGEF2	Q04759	PRKCQ	S1248	R1246C	1246	Missense	proximal	-2	no	1.374	0.671	EPSD	COSMIC;GDSC;CCLE	1.204	Loss
AGC_PKC_PKCd_PRKCQ_ST	Q9Y4G8	RAPGEF2	Q04759	PRKCQ	S1251	R1246C	1246	Missense	distal	-5	no	1.215	0.954	EPSD	COSMIC;GDSC;CCLE	1.204	Loss
AGC_PKC_PKCd_PRKCQ_ST	Q9Y4G8	RAPGEF2	Q04759	PRKCQ	S1251	D1258N	1258	Missense	distal	7	no	1.215	1.198	EPSD	COSMIC	1.204	Loss
AGC_PKC_PKCd_PRKCQ_ST	Q9Y4G8	RAPGEF2	Q04759	PRKCQ	S1325	E1318Q	1318	Missense	distal	-7	no	1.277	1.273	EPSD	COSMIC	1.204	Down-regulation
AGC_PKC_PKCd_PRKCQ_ST	Q9Y4G8	RAPGEF2	Q04759	PRKCQ	S1325	G1331R	1331	Missense	distal	6	no	1.277	1.329	EPSD	COSMIC	1.204	Up-regulation
AGC_PKC_PKCd_PRKCQ_ST	Q9Y4G8	RAPGEF2	Q04759	PRKCQ	S1337	G1334R	1334	Missense	distal	-3	no	0.301	1.619	EPSD	COSMIC	1.204	Gain
AGC_PKC_PKCd_PRKCQ_ST	Q13191	CBLB	Q04759	PRKCQ	S277	G281R	281	Missense	distal	4	no	1.339	1.522	EPSD	COSMIC	1.204	Up-regulation
AGC_PKC_PKCd_PRKCQ_ST	Q13191	CBLB	Q04759	PRKCQ	S277	I284M	284	Missense	distal	7	no	1.339	1.314	EPSD	COSMIC	1.204	Down-regulation
AGC_PKC_PKCd_PRKCQ_ST	Q13191	CBLB	Q04759	PRKCQ	S277	P280H	280	Missense	distal	3	no	1.339	1.336	EPSD	COSMIC	1.204	Down-regulation
AGC_PKC_PKCd_PRKCQ_ST	Q13191	CBLB	Q04759	PRKCQ	S282	G281R	281	Missense	proximal	-1	no	1.782	1.794	PhosphoSitePlus	COSMIC	1.204	Up-regulation
AGC_PKC_PKCd_PRKCQ_ST	Q13191	CBLB	Q04759	PRKCQ	S282	I284M	284	Missense	proximal	2	no	1.782	1.826	PhosphoSitePlus	COSMIC	1.204	Up-regulation
AGC_PKC_PKCd_PRKCQ_ST	Q13191	CBLB	Q04759	PRKCQ	S282	R286Q	286	Missense	distal	4	no	1.782	1.629	PhosphoSitePlus	COSMIC	1.204	Down-regulation
AGC_PKC_PKCd_PRKCQ_ST	Q13191	CBLB	Q04759	PRKCQ	S282	P280H	280	Missense	proximal	-2	no	1.782	1.715	PhosphoSitePlus	COSMIC	1.204	Down-regulation
AGC_PKC_PKCd_PRKCQ_ST	Q13191	CBLB	Q04759	PRKCQ	S533	P534S	534	Missense	proximal	1	no	1.241	1.240	EPSD	COSMIC	1.204	Down-regulation
AGC_PKC_PKCd_PRKCQ_ST	Q13191	CBLB	Q04759	PRKCQ	S533	R538C	538	Missense	distal	5	no	1.241	1.212	EPSD	COSMIC	1.204	Down-regulation
AGC_PKC_PKCd_PRKCQ_ST	Q13191	CBLB	Q04759	PRKCQ	S634	R640W	640	Missense	distal	6	no	1.742	1.695	EPSD	COSMIC	1.204	Down-regulation
AGC_PKC_PKCd_PRKCQ_ST	Q13191	CBLB	Q04759	PRKCQ	S634	L638Q	638	Missense	distal	4	no	1.742	1.767	EPSD	COSMIC	1.204	Up-regulation
AGC_PKC_PKCd_PRKCQ_ST	Q13191	CBLB	Q04759	PRKCQ	S634	L638P	638	Missense	distal	4	no	1.742	1.787	EPSD	COSMIC	1.204	Up-regulation
AGC_PKC_PKCd_PRKCQ_ST	Q13191	CBLB	Q04759	PRKCQ	S656	L660F	660	Missense	distal	4	no	1.350	1.381	EPSD	COSMIC	1.204	Up-regulation
AGC_PKC_PKCd_PRKCQ_ST	Q13191	CBLB	Q04759	PRKCQ	S656	G658A	658	Missense	proximal	2	no	1.350	1.392	EPSD	COSMIC	1.204	Up-regulation
AGC_PKC_PKCd_PRKCQ_ST	Q13191	CBLB	Q04759	PRKCQ	S656	L649S	649	Missense	distal	-7	no	1.350	1.346	EPSD	COSMIC	1.204	Down-regulation
AGC_PKC_PKCd_PRKCQ_ST	Q13191	CBLB	Q04759	PRKCQ	S656	G661A	661	Missense	distal	5	no	1.350	1.358	EPSD	COSMIC	1.204	Up-regulation
AGC_PKC_PKCd_PRKCQ_ST	Q13191	CBLB	Q04759	PRKCQ	S672	P673L	673	Missense	proximal	1	no	1.394	1.390	EPSD	COSMIC	1.204	Down-regulation
AGC_PKC_PKCd_PRKCQ_ST	Q13191	CBLB	Q04759	PRKCQ	S672	P668L	668	Missense	distal	-4	no	1.394	1.376	EPSD	COSMIC	1.204	Down-regulation
AGC_PKC_PKCd_PRKCQ_ST	Q13191	CBLB	Q04759	PRKCQ	S672	P676H	676	Missense	distal	4	no	1.394	1.377	EPSD	COSMIC	1.204	Down-regulation
AGC_PKC_PKCd_PRKCQ_ST	Q13191	CBLB	Q04759	PRKCQ	S793	P789L	789	Missense	distal	-4	no	1.494	1.476	EPSD	COSMIC	1.204	Down-regulation
AGC_PKC_PKCd_PRKCQ_ST	Q13191	CBLB	Q04759	PRKCQ	S793	D787E	787	Missense	distal	-6	no	1.494	1.497	EPSD	COSMIC	1.204	Up-regulation
AGC_PKC_PKCd_PRKCQ_ST	Q13191	CBLB	Q04759	PRKCQ	S800	L804F	804	Missense	distal	4	no	1.372	1.403	EPSD	COSMIC	1.204	Up-regulation
AGC_PKC_PKCd_PRKCQ_ST	Q13191	CBLB	Q04759	PRKCQ	S846	R844W	844	Missense	proximal	-2	no	1.221	0.506	EPSD	COSMIC	1.204	Loss
AGC_PKC_PKCd_PRKCQ_ST	Q13191	CBLB	Q04759	PRKCQ	S846	R844Q	844	Missense	proximal	-2	no	1.221	0.565	EPSD	COSMIC	1.204	Loss
AGC_PKC_PKCd_PRKCQ_ST	Q13191	CBLB	Q04759	PRKCQ	S846	L851I	851	Missense	distal	5	no	1.221	1.222	EPSD	COSMIC	1.204	Up-regulation
AGC_PKC_PKCd_PRKCQ_ST	Q13191	CBLB	Q04759	PRKCQ	S847	R844W	844	Missense	distal	-3	no	1.864	0.552	EPSD	COSMIC	1.204	Loss
AGC_PKC_PKCd_PRKCQ_ST	Q13191	CBLB	Q04759	PRKCQ	S847	R844Q	844	Missense	distal	-3	no	1.864	0.636	EPSD	COSMIC	1.204	Loss
AGC_PKC_PKCd_PRKCQ_ST	Q13191	CBLB	Q04759	PRKCQ	S847	L851I	851	Missense	distal	4	no	1.864	1.871	EPSD	COSMIC	1.204	Up-regulation
AGC_PKC_PKCd_PRKCQ_ST	Q13191	CBLB	Q04759	PRKCQ	S886	Y889C	889	Missense	distal	3	no	1.420	1.418	EPSD	COSMIC	1.204	Down-regulation
AGC_PKC_PKCd_PRKCQ_ST	Q13191	CBLB	Q04759	PRKCQ	S886	N883K	883	Missense	distal	-3	no	1.420	2.183	EPSD	COSMIC	1.204	Up-regulation
AGC_PKC_PKCd_PRKCQ_ST	Q13191	CBLB	Q04759	PRKCQ	S886	R884K	884	Missense	proximal	-2	no	1.420	1.176	EPSD	COSMIC	1.204	Loss
AGC_PKC_PKCd_PRKCQ_ST	Q13191	CBLB	Q04759	PRKCQ	S896	A903T	903	Missense	distal	7	no	1.198	1.230	EPSD	COSMIC	1.204	Gain
AGC_PKC_PKCd_PRKCQ_ST	Q13191	CBLB	Q04759	PRKCQ	S896	A903S	903	Missense	distal	7	no	1.198	1.208	EPSD	COSMIC;GDSC;CCLE	1.204	Gain
AGC_PKC_PKCd_PRKCQ_ST	Q13191	CBLB	Q04759	PRKCQ	S977	P973L	973	Missense	distal	-4	no	1.450	1.432	EPSD	COSMIC	1.204	Down-regulation
AGC_PKC_PKCd_PRKCQ_ST	Q13191	CBLB	Q04759	PRKCQ	S977	S977F	977	Missense	central	0	yes	1.450	0.000	EPSD	COSMIC	1.204	Loss
AGC_PKC_PKCd_PRKCQ_ST	Q13191	CBLB	Q04759	PRKCQ	S977	R979H	979	Missense	proximal	2	no	1.450	1.225	EPSD	COSMIC	1.204	Down-regulation
AGC_PKC_PKCd_PRKCQ_ST	Q5JVS0	HABP4	Q04759	PRKCQ	S316	S320F	320	Missense	distal	4	no	1.524	1.523	EPSD	COSMIC	1.204	Down-regulation
AGC_PKC_PKCd_PRKCQ_ST	Q5JVS0	HABP4	Q04759	PRKCQ	S316	S320P	320	Missense	distal	4	no	1.524	1.537	EPSD	COSMIC	1.204	Up-regulation
AGC_PKC_PKCd_PRKCQ_ST	Q5JVS0	HABP4	Q04759	PRKCQ	S316	R312Q	312	Missense	distal	-4	no	1.524	1.476	EPSD	COSMIC;GDSC;CCLE	1.204	Down-regulation
AGC_PKC_PKCd_PRKCQ_ST	Q5JVS0	HABP4	Q04759	PRKCQ	T375	R379Q	379	Missense	distal	4	no	1.246	1.093	PhosphoSitePlus;EPSD	COSMIC	1.204	Loss
AGC_PKC_PKCd_PRKCQ_ST	Q5JVS0	HABP4	Q04759	PRKCQ	T375	R379W	379	Missense	distal	4	no	1.246	1.075	PhosphoSitePlus;EPSD	COSMIC;GDSC	1.204	Loss
AGC_PKC_PKCd_PRKCQ_ST	Q5JVS0	HABP4	Q04759	PRKCQ	T375	G377A	377	Missense	proximal	2	no	1.246	1.288	PhosphoSitePlus;EPSD	COSMIC	1.204	Up-regulation
AGC_PKC_PKCd_PRKCQ_ST	Q9UEW8	STK39	Q04759	PRKCQ	S142	L141V	141	Missense	proximal	-1	no	1.248	1.246	EPSD	COSMIC	1.204	Down-regulation
AGC_PKC_PKCd_PRKCQ_ST	Q9UEW8	STK39	Q04759	PRKCQ	S323	P322S	322	Missense	proximal	-1	no	1.819	1.820	PhosphoSitePlus;EPSD	COSMIC	1.204	Up-regulation
AGC_PKC_PKCd_PRKCQ_ST	P32942	ICAM3	Q04759	PRKCQ	S518	E512G	512	Missense	distal	-6	no	2.100	2.091	PhosphoSitePlus	COSMIC	1.204	Down-regulation
AGC_PKC_PKCd_PRKCQ_ST	O14974	PPP1R12A	Q04759	PRKCQ	S299	D296N	296	Missense	distal	-3	no	1.172	1.392	EPSD	COSMIC	1.204	Gain
AGC_PKC_PKCd_PRKCQ_ST	O14974	PPP1R12A	Q04759	PRKCQ	S332	A331V	331	Missense	proximal	-1	no	1.700	1.696	EPSD	COSMIC	1.204	Down-regulation
AGC_PKC_PKCd_PRKCQ_ST	O14974	PPP1R12A	Q04759	PRKCQ	S332	R333H	333	Missense	proximal	1	no	1.700	1.683	EPSD	COSMIC	1.204	Down-regulation
AGC_PKC_PKCd_PRKCQ_ST	O14974	PPP1R12A	Q04759	PRKCQ	S332	I334L	334	Missense	proximal	2	no	1.700	1.688	EPSD	COSMIC	1.204	Down-regulation
AGC_PKC_PKCd_PRKCQ_ST	O14974	PPP1R12A	Q04759	PRKCQ	S336	A331V	331	Missense	distal	-5	no	1.562	1.501	EPSD	COSMIC	1.204	Down-regulation
AGC_PKC_PKCd_PRKCQ_ST	O14974	PPP1R12A	Q04759	PRKCQ	S336	R333H	333	Missense	distal	-3	no	1.562	0.449	EPSD	COSMIC	1.204	Loss
AGC_PKC_PKCd_PRKCQ_ST	O14974	PPP1R12A	Q04759	PRKCQ	S336	I334L	334	Missense	proximal	-2	no	1.562	1.544	EPSD	COSMIC	1.204	Down-regulation
AGC_PKC_PKCd_PRKCQ_ST	O14974	PPP1R12A	Q04759	PRKCQ	S432	R428K	428	Missense	distal	-4	no	1.559	1.534	EPSD	COSMIC;GDSC;CCLE	1.204	Down-regulation
AGC_PKC_PKCd_PRKCQ_ST	O14974	PPP1R12A	Q04759	PRKCQ	S472	R469C	469	Missense	distal	-3	no	1.692	0.393	EPSD	COSMIC	1.204	Loss
AGC_PKC_PKCd_PRKCQ_ST	O14974	PPP1R12A	Q04759	PRKCQ	S472	A465S	465	Missense	distal	-7	no	1.692	1.693	EPSD	COSMIC	1.204	Up-regulation
AGC_PKC_PKCd_PRKCQ_ST	O14974	PPP1R12A	Q04759	PRKCQ	S472	S478C	478	Missense	distal	6	no	1.692	1.674	EPSD	COSMIC	1.204	Down-regulation
AGC_PKC_PKCd_PRKCQ_ST	O14974	PPP1R12A	Q04759	PRKCQ	S477	S478C	478	Missense	proximal	1	no	1.608	1.604	EPSD	COSMIC	1.204	Down-regulation
AGC_PKC_PKCd_PRKCQ_ST	O14974	PPP1R12A	Q04759	PRKCQ	S478	S478C	478	Missense	central	0	yes	1.328	0.000	EPSD	COSMIC	1.204	Loss
AGC_PKC_PKCd_PRKCQ_ST	O14974	PPP1R12A	Q04759	PRKCQ	S507	T508S	508	Missense	proximal	1	no	2.184	2.186	EPSD	COSMIC	1.204	Up-regulation
AGC_PKC_PKCd_PRKCQ_ST	O14974	PPP1R12A	Q04759	PRKCQ	S519	T524A	524	Missense	distal	5	no	1.411	1.418	EPSD	COSMIC;GDSC;CCLE	1.204	Up-regulation
AGC_PKC_PKCd_PRKCQ_ST	O14974	PPP1R12A	Q04759	PRKCQ	S520	T524A	524	Missense	distal	4	no	1.331	1.354	EPSD	COSMIC;GDSC;CCLE	1.204	Up-regulation
AGC_PKC_PKCd_PRKCQ_ST	O14974	PPP1R12A	Q04759	PRKCQ	S554	S554F	554	Missense	central	0	yes	1.320	0.000	EPSD	COSMIC	1.204	Loss
AGC_PKC_PKCd_PRKCQ_ST	O14974	PPP1R12A	Q04759	PRKCQ	S554	S554C	554	Missense	central	0	yes	1.320	0.000	EPSD	COSMIC	1.204	Loss
AGC_PKC_PKCd_PRKCQ_ST	O14974	PPP1R12A	Q04759	PRKCQ	S668	R663I	663	Missense	distal	-5	no	2.668	2.401	EPSD	COSMIC	1.204	Down-regulation
AGC_PKC_PKCd_PRKCQ_ST	O14974	PPP1R12A	Q04759	PRKCQ	S686	E679Q	679	Missense	distal	-7	no	1.839	1.834	EPSD	COSMIC	1.204	Down-regulation
AGC_PKC_PKCd_PRKCQ_ST	O14974	PPP1R12A	Q04759	PRKCQ	S686	E679K	679	Missense	distal	-7	no	1.839	1.821	EPSD	COSMIC;CCLE	1.204	Down-regulation
AGC_PKC_PKCd_PRKCQ_ST	O14974	PPP1R12A	Q04759	PRKCQ	S692	R694I	694	Missense	proximal	2	no	1.489	1.222	EPSD	COSMIC	1.204	Down-regulation
AGC_PKC_PKCd_PRKCQ_ST	O14974	PPP1R12A	Q04759	PRKCQ	S695	R694I	694	Missense	proximal	-1	no	1.491	1.478	EPSD	COSMIC	1.204	Down-regulation
AGC_PKC_PKCd_PRKCQ_ST	O14974	PPP1R12A	Q04759	PRKCQ	T696	R694I	694	Missense	proximal	-2	no	1.373	0.640	EPSD	COSMIC	1.204	Loss
AGC_PKC_PKCd_PRKCQ_ST	O14974	PPP1R12A	Q04759	PRKCQ	S716	R718Q	718	Missense	proximal	2	no	2.440	2.202	EPSD	COSMIC	1.204	Down-regulation
AGC_PKC_PKCd_PRKCQ_ST	O14974	PPP1R12A	Q04759	PRKCQ	S852	R851H	851	Missense	proximal	-1	no	2.201	2.191	EPSD	COSMIC	1.204	Down-regulation
AGC_PKC_PKCd_PRKCQ_ST	O14974	PPP1R12A	Q04759	PRKCQ	S852	R851C	851	Missense	proximal	-1	no	2.201	2.189	EPSD	COSMIC	1.204	Down-regulation
AGC_PKC_PKCd_PRKCQ_ST	O14974	PPP1R12A	Q04759	PRKCQ	T853	R851H	851	Missense	proximal	-2	no	1.351	0.748	PhosphoSitePlus	COSMIC	1.204	Loss
AGC_PKC_PKCd_PRKCQ_ST	O14974	PPP1R12A	Q04759	PRKCQ	T853	R851C	851	Missense	proximal	-2	no	1.351	0.647	PhosphoSitePlus	COSMIC	1.204	Loss
AGC_PKC_PKCd_PRKCQ_ST	O14974	PPP1R12A	Q04759	PRKCQ	S903	G898D	898	Missense	distal	-5	no	1.716	1.702	EPSD	COSMIC	1.204	Down-regulation
AGC_PKC_PKCd_PRKCQ_ST	O14974	PPP1R12A	Q04759	PRKCQ	S903	S910T	910	Missense	distal	7	no	1.716	1.738	EPSD	COSMIC	1.204	Up-regulation
AGC_PKC_PKCd_PRKCQ_ST	O14974	PPP1R12A	Q04759	PRKCQ	S921	S922P	922	Missense	proximal	1	no	1.657	1.658	EPSD	COSMIC	1.204	Up-regulation
AGC_PKC_PKCd_PRKCQ_ST	O14974	PPP1R12A	Q04759	PRKCQ	S922	S922P	922	Missense	central	0	yes	1.269	0.000	EPSD	COSMIC	1.204	Loss
AGC_PKC_PKCd_PRKCQ_ST	O14974	PPP1R12A	Q04759	PRKCQ	S929	S922P	922	Missense	distal	-7	no	1.417	1.414	EPSD	COSMIC	1.204	Down-regulation
AGC_PKC_PKCd_PRKCQ_ST	O14974	PPP1R12A	Q04759	PRKCQ	S929	D931N	931	Missense	proximal	2	no	1.417	1.466	EPSD	COSMIC	1.204	Up-regulation
AGC_PKC_PKCd_PRKCQ_ST	Q15052	ARHGEF6	Q04759	PRKCQ	S101	L103P	103	Missense	proximal	2	no	1.420	1.501	EPSD	COSMIC	1.204	Up-regulation
AGC_PKC_PKCd_PRKCQ_ST	Q15052	ARHGEF6	Q04759	PRKCQ	S101	N95S	95	Missense	distal	-6	no	1.420	1.375	EPSD	COSMIC	1.204	Down-regulation
AGC_PKC_PKCd_PRKCQ_ST	Q15052	ARHGEF6	Q04759	PRKCQ	S150	Q149E	149	Missense	proximal	-1	no	1.234	1.232	EPSD	COSMIC	1.204	Down-regulation
AGC_PKC_PKCd_PRKCQ_ST	Q15052	ARHGEF6	Q04759	PRKCQ	S150	Q147H	147	Missense	distal	-3	no	1.234	1.349	EPSD	COSMIC	1.204	Up-regulation
AGC_PKC_PKCd_PRKCQ_ST	Q15052	ARHGEF6	Q04759	PRKCQ	S220	P226S	226	Missense	distal	6	no	1.562	1.566	EPSD	COSMIC	1.204	Up-regulation
AGC_PKC_PKCd_PRKCQ_ST	Q15052	ARHGEF6	Q04759	PRKCQ	S220	S219C	219	Missense	proximal	-1	no	1.562	1.558	EPSD	COSMIC	1.204	Down-regulation
AGC_PKC_PKCd_PRKCQ_ST	Q15052	ARHGEF6	Q04759	PRKCQ	S220	S220R	220	Missense	central	0	yes	1.562	0.000	EPSD	COSMIC	1.204	Loss
AGC_PKC_PKCd_PRKCQ_ST	Q15052	ARHGEF6	Q04759	PRKCQ	S225	P226S	226	Missense	proximal	1	no	2.148	2.147	PhosphoSitePlus;EPSD	COSMIC	1.204	Down-regulation
AGC_PKC_PKCd_PRKCQ_ST	Q15052	ARHGEF6	Q04759	PRKCQ	S225	S219C	219	Missense	distal	-6	no	2.148	2.216	PhosphoSitePlus;EPSD	COSMIC	1.204	Up-regulation
AGC_PKC_PKCd_PRKCQ_ST	Q15052	ARHGEF6	Q04759	PRKCQ	S225	V229D	229	Missense	distal	4	no	2.148	2.150	PhosphoSitePlus;EPSD	COSMIC	1.204	Up-regulation
AGC_PKC_PKCd_PRKCQ_ST	Q15052	ARHGEF6	Q04759	PRKCQ	S225	S220R	220	Missense	distal	-5	no	2.148	2.338	PhosphoSitePlus;EPSD	COSMIC	1.204	Up-regulation
AGC_PKC_PKCd_PRKCQ_ST	Q15052	ARHGEF6	Q04759	PRKCQ	S488	M487R	487	Missense	proximal	-1	no	1.525	1.535	EPSD;PhosphoSitePlus	COSMIC;GDSC;CCLE	1.204	Up-regulation
AGC_PKC_PKCd_PRKCQ_ST	Q15052	ARHGEF6	Q04759	PRKCQ	S488	A483E	483	Missense	distal	-5	no	1.525	1.473	EPSD;PhosphoSitePlus	COSMIC	1.204	Down-regulation
AGC_PKC_PKCd_PRKCQ_ST	Q15052	ARHGEF6	Q04759	PRKCQ	S488	P485H	485	Missense	distal	-3	no	1.525	1.398	EPSD;PhosphoSitePlus	COSMIC	1.204	Down-regulation
AGC_PKC_PKCd_PRKCQ_ST	Q15052	ARHGEF6	Q04759	PRKCQ	S488	S488R	488	Missense	central	0	yes	1.525	0.000	EPSD;PhosphoSitePlus	COSMIC	1.204	Loss
AGC_PKC_PKCd_PRKCQ_ST	Q15052	ARHGEF6	Q04759	PRKCQ	S488	R486L	486	Missense	proximal	-2	no	1.525	0.775	EPSD;PhosphoSitePlus	COSMIC	1.204	Loss
AGC_PKC_PKCd_PRKCQ_ST	Q15052	ARHGEF6	Q04759	PRKCQ	S560	S554T	554	Missense	distal	-6	no	1.452	1.530	EPSD	COSMIC	1.204	Up-regulation
AGC_PKC_PKCd_PRKCQ_ST	Q15052	ARHGEF6	Q04759	PRKCQ	S560	S561L	561	Missense	proximal	1	no	1.452	1.448	EPSD	COSMIC	1.204	Down-regulation
AGC_PKC_PKCd_PRKCQ_ST	Q15052	ARHGEF6	Q04759	PRKCQ	S560	A566T	566	Missense	distal	6	no	1.452	1.432	EPSD	COSMIC	1.204	Down-regulation
AGC_PKC_PKCd_PRKCQ_ST	Q15052	ARHGEF6	Q04759	PRKCQ	S560	A566S	566	Missense	distal	6	no	1.452	1.458	EPSD	COSMIC	1.204	Up-regulation
AGC_PKC_PKCd_PRKCQ_ST	Q15052	ARHGEF6	Q04759	PRKCQ	S561	S554T	554	Missense	distal	-7	no	1.365	1.366	EPSD	COSMIC	1.204	Up-regulation
AGC_PKC_PKCd_PRKCQ_ST	Q15052	ARHGEF6	Q04759	PRKCQ	S561	S561L	561	Missense	central	0	yes	1.365	0.000	EPSD	COSMIC	1.204	Loss
AGC_PKC_PKCd_PRKCQ_ST	Q15052	ARHGEF6	Q04759	PRKCQ	S561	A566T	566	Missense	distal	5	no	1.365	1.358	EPSD	COSMIC	1.204	Down-regulation
AGC_PKC_PKCd_PRKCQ_ST	Q15052	ARHGEF6	Q04759	PRKCQ	S561	A566S	566	Missense	distal	5	no	1.365	1.364	EPSD	COSMIC	1.204	Down-regulation
AGC_PKC_PKCd_PRKCQ_ST	Q15052	ARHGEF6	Q04759	PRKCQ	S620	K617M	617	Missense	distal	-3	no	1.272	0.532	EPSD	COSMIC	1.204	Loss
AGC_PKC_PKCd_PRKCQ_ST	Q15052	ARHGEF6	Q04759	PRKCQ	S620	T625M	625	Missense	distal	5	no	1.272	1.278	EPSD	COSMIC	1.204	Up-regulation
AGC_PKC_PKCd_PRKCQ_ST	Q15052	ARHGEF6	Q04759	PRKCQ	S620	S620R	620	Missense	central	0	yes	1.272	0.000	EPSD	COSMIC	1.204	Loss
AGC_PKC_PKCd_PRKCQ_ST	Q15052	ARHGEF6	Q04759	PRKCQ	S620	K627N	627	Missense	distal	7	no	1.272	1.308	EPSD	COSMIC	1.204	Up-regulation
AGC_PKC_PKCd_PRKCQ_ST	Q15052	ARHGEF6	Q04759	PRKCQ	S620	K617N	617	Missense	distal	-3	no	1.272	0.508	EPSD	COSMIC	1.204	Loss
AGC_PKC_PKCd_PRKCQ_ST	Q15052	ARHGEF6	Q04759	PRKCQ	S622	S620R	620	Missense	proximal	-2	no	1.156	1.764	EPSD	COSMIC	1.204	Gain
AGC_PKC_PKCd_PRKCQ_ST	Q15052	ARHGEF6	Q04759	PRKCQ	T635	R637K	637	Missense	proximal	2	no	1.566	1.484	EPSD	COSMIC	1.204	Down-regulation
AGC_PKC_PKCd_PRKCQ_ST	Q15052	ARHGEF6	Q04759	PRKCQ	S640	R647W	647	Missense	distal	7	no	1.823	1.922	EPSD	COSMIC	1.204	Up-regulation
AGC_PKC_PKCd_PRKCQ_ST	Q15052	ARHGEF6	Q04759	PRKCQ	S640	R637K	637	Missense	distal	-3	no	1.823	1.405	EPSD	COSMIC	1.204	Down-regulation
AGC_PKC_PKCd_PRKCQ_ST	Q15052	ARHGEF6	Q04759	PRKCQ	S649	R647W	647	Missense	proximal	-2	no	1.243	0.529	EPSD	COSMIC	1.204	Loss
AGC_PKC_PKCd_PRKCQ_ST	Q15052	ARHGEF6	Q04759	PRKCQ	S649	T650S	650	Missense	proximal	1	no	1.243	1.245	EPSD	COSMIC;GDSC;CCLE	1.204	Up-regulation
AGC_PKC_PKCd_PRKCQ_ST	Q15052	ARHGEF6	Q04759	PRKCQ	S649	E654K	654	Missense	distal	5	no	1.243	1.262	EPSD	COSMIC;GDSC;CCLE	1.204	Up-regulation
AGC_PKC_PKCd_PRKCQ_ST	Q15052	ARHGEF6	Q04759	PRKCQ	T650	E654K	654	Missense	distal	4	no	1.117	1.241	EPSD	COSMIC;GDSC;CCLE	1.204	Gain
AGC_PKC_PKCd_PRKCQ_ST	Q15052	ARHGEF6	Q04759	PRKCQ	S679	G677R	677	Missense	proximal	-2	no	1.116	1.839	EPSD	COSMIC	1.204	Gain
AGC_PKC_PKCd_PRKCQ_ST	Q15052	ARHGEF6	Q04759	PRKCQ	S684	P691S	691	Missense	distal	7	no	2.236	2.241	EPSD	COSMIC;GDSC;CCLE	1.204	Up-regulation
AGC_PKC_PKCd_PRKCQ_ST	Q15052	ARHGEF6	Q04759	PRKCQ	S684	S684C	684	Missense	central	0	yes	2.236	0.000	EPSD	COSMIC	1.204	Loss
AGC_PKC_PKCd_PRKCQ_ST	Q15052	ARHGEF6	Q04759	PRKCQ	S684	G677R	677	Missense	distal	-7	no	2.236	2.211	EPSD	COSMIC	1.204	Down-regulation
AGC_PKC_PKCd_PRKCQ_ST	Q15052	ARHGEF6	Q04759	PRKCQ	S684	D683V	683	Missense	proximal	-1	no	2.236	2.234	EPSD	COSMIC	1.204	Down-regulation
AGC_PKC_PKCd_PRKCQ_ST	Q15052	ARHGEF6	Q04759	PRKCQ	S684	L690I	690	Missense	distal	6	no	2.236	2.237	EPSD	COSMIC	1.204	Up-regulation
AGC_PKC_PKCd_PRKCQ_ST	Q8IV61	RASGRP3	Q04759	PRKCQ	T133	R135T	135	Missense	proximal	2	no	2.341	2.079	PhosphoSitePlus	COSMIC;CCLE	1.204	Down-regulation
AGC_PKC_PKCd_PRKCQ_ST	Q8IV61	RASGRP3	Q04759	PRKCQ	T133	M129I	129	Missense	distal	-4	no	2.341	2.326	PhosphoSitePlus	COSMIC	1.204	Down-regulation
AGC_PKC_PKCd_PRKCQ_ST	Q8IV61	RASGRP3	Q04759	PRKCQ	S385	S387L	387	Missense	proximal	2	no	1.489	1.466	EPSD	COSMIC	1.204	Down-regulation
AGC_PKC_PKCd_PRKCQ_ST	Q8IV61	RASGRP3	Q04759	PRKCQ	S385	S387P	387	Missense	proximal	2	no	1.489	1.548	EPSD	COSMIC	1.204	Up-regulation
AGC_PKC_PKCd_PRKCQ_ST	Q8IV61	RASGRP3	Q04759	PRKCQ	S385	P392H	392	Missense	distal	7	no	1.489	1.498	EPSD	COSMIC	1.204	Up-regulation
AGC_PKC_PKCd_PRKCQ_ST	Q8IV61	RASGRP3	Q04759	PRKCQ	S385	Q388R	388	Missense	distal	3	no	1.489	1.507	EPSD	COSMIC	1.204	Up-regulation
AGC_PKC_PKCd_PRKCQ_ST	Q8IV61	RASGRP3	Q04759	PRKCQ	S385	S385Y	385	Missense	central	0	yes	1.489	0.000	EPSD	COSMIC	1.204	Loss
AGC_PKC_PKCd_PRKCQ_ST	Q8IV61	RASGRP3	Q04759	PRKCQ	S385	K386I	386	Missense	proximal	1	no	1.489	1.480	EPSD	COSMIC	1.204	Down-regulation
AGC_PKC_PKCd_PRKCQ_ST	Q8IV61	RASGRP3	Q04759	PRKCQ	S391	Q388R	388	Missense	distal	-3	no	0.787	2.015	EPSD	COSMIC	1.204	Gain
AGC_PKC_PKCd_PRKCQ_ST	Q8IV61	RASGRP3	Q04759	PRKCQ	S552	P551L	551	Missense	proximal	-1	no	1.608	1.605	EPSD	COSMIC	1.204	Down-regulation
AGC_PKC_PKCd_PRKCQ_ST	Q8IV61	RASGRP3	Q04759	PRKCQ	S552	P551S	551	Missense	proximal	-1	no	1.608	1.610	EPSD	COSMIC	1.204	Up-regulation
AGC_PKC_PKCd_PRKCQ_ST	Q8IV61	RASGRP3	Q04759	PRKCQ	S552	A548S	548	Missense	distal	-4	no	1.608	1.618	EPSD	COSMIC	1.204	Up-regulation
AGC_PKC_PKCd_PRKCQ_ST	Q8IV61	RASGRP3	Q04759	PRKCQ	S638	A645T	645	Missense	distal	7	no	1.681	1.713	EPSD	COSMIC	1.204	Up-regulation
AGC_PKC_PKCd_PRKCQ_ST	Q8IV61	RASGRP3	Q04759	PRKCQ	S638	A644T	644	Missense	distal	6	no	1.681	1.662	EPSD	COSMIC	1.204	Down-regulation
AGC_PKA_PRKACB_ST	Q01130	SRSF2	P22694	PRKACB	S121	S128N	128	Missense	distal	7	no	3.788	3.772	PhosphoSitePlus;EPSD	COSMIC	2.323	Down-regulation
AGC_PKA_PRKACB_ST	Q01130	SRSF2	P22694	PRKACB	S121	R117G	117	Missense	distal	-4	no	3.788	3.707	PhosphoSitePlus;EPSD	COSMIC	2.323	Down-regulation
AGC_PKA_PRKACB_ST	Q01130	SRSF2	P22694	PRKACB	S121	R125H	125	Missense	distal	4	no	3.788	3.785	PhosphoSitePlus;EPSD	COSMIC	2.323	Down-regulation
AGC_PKA_PRKACB_ST	Q01130	SRSF2	P22694	PRKACB	S121	R123W	123	Missense	proximal	2	no	3.788	3.811	PhosphoSitePlus;EPSD	COSMIC	2.323	Up-regulation
AGC_PKA_PRKACB_ST	Q01130	SRSF2	P22694	PRKACB	S121	R127C	127	Missense	distal	6	no	3.788	3.820	PhosphoSitePlus;EPSD	COSMIC	2.323	Up-regulation
AGC_PKA_PRKACB_ST	Q01130	SRSF2	P22694	PRKACB	S128	R125T	125	Missense	distal	-3	no	2.373	0.155	EPSD;PhosphoSitePlus	COSMIC	2.323	Loss
AGC_PKA_PRKACB_ST	Q01130	SRSF2	P22694	PRKACB	S128	S128N	128	Missense	central	0	yes	2.373	0.000	EPSD;PhosphoSitePlus	COSMIC	2.323	Loss
AGC_PKA_PRKACB_ST	Q01130	SRSF2	P22694	PRKACB	S128	S130F	130	Missense	proximal	2	no	2.373	2.375	EPSD;PhosphoSitePlus	COSMIC	2.323	Up-regulation
AGC_PKA_PRKACB_ST	Q01130	SRSF2	P22694	PRKACB	S128	S132R	132	Missense	distal	4	no	2.373	2.377	EPSD;PhosphoSitePlus	COSMIC	2.323	Up-regulation
AGC_PKA_PRKACB_ST	Q01130	SRSF2	P22694	PRKACB	S128	R125H	125	Missense	distal	-3	no	2.373	0.515	EPSD;PhosphoSitePlus	COSMIC	2.323	Loss
AGC_PKA_PRKACB_ST	Q01130	SRSF2	P22694	PRKACB	S128	R123W	123	Missense	distal	-5	no	2.373	2.452	EPSD;PhosphoSitePlus	COSMIC	2.323	Up-regulation
AGC_PKA_PRKACB_ST	Q01130	SRSF2	P22694	PRKACB	S128	R127C	127	Missense	proximal	-1	no	2.373	2.396	EPSD;PhosphoSitePlus	COSMIC	2.323	Up-regulation
AGC_PKA_PRKACB_ST	Q01130	SRSF2	P22694	PRKACB	S130	R125T	125	Missense	distal	-5	no	2.496	2.452	EPSD;PhosphoSitePlus	COSMIC	2.323	Down-regulation
AGC_PKA_PRKACB_ST	Q01130	SRSF2	P22694	PRKACB	S130	S128N	128	Missense	proximal	-2	no	2.496	2.698	EPSD;PhosphoSitePlus	COSMIC	2.323	Up-regulation
AGC_PKA_PRKACB_ST	Q01130	SRSF2	P22694	PRKACB	S130	S130F	130	Missense	central	0	yes	2.496	0.000	EPSD;PhosphoSitePlus	COSMIC	2.323	Loss
AGC_PKA_PRKACB_ST	Q01130	SRSF2	P22694	PRKACB	S130	S132R	132	Missense	proximal	2	no	2.496	2.477	EPSD;PhosphoSitePlus	COSMIC	2.323	Down-regulation
AGC_PKA_PRKACB_ST	Q01130	SRSF2	P22694	PRKACB	S130	R137T	137	Missense	distal	7	no	2.496	2.493	EPSD;PhosphoSitePlus	COSMIC	2.323	Down-regulation
AGC_PKA_PRKACB_ST	Q01130	SRSF2	P22694	PRKACB	S130	R125H	125	Missense	distal	-5	no	2.496	2.650	EPSD;PhosphoSitePlus	COSMIC	2.323	Up-regulation
AGC_PKA_PRKACB_ST	Q01130	SRSF2	P22694	PRKACB	S130	R123W	123	Missense	distal	-7	no	2.496	2.318	EPSD;PhosphoSitePlus	COSMIC	2.323	Loss
AGC_PKA_PRKACB_ST	Q01130	SRSF2	P22694	PRKACB	S130	R127C	127	Missense	distal	-3	no	2.496	0.469	EPSD;PhosphoSitePlus	COSMIC	2.323	Loss
AGC_PKA_PRKACB_ST	Q01130	SRSF2	P22694	PRKACB	S134	S128N	128	Missense	distal	-6	no	2.934	2.963	EPSD	COSMIC	2.323	Up-regulation
AGC_PKA_PRKACB_ST	Q01130	SRSF2	P22694	PRKACB	S134	S130F	130	Missense	distal	-4	no	2.934	2.950	EPSD	COSMIC	2.323	Up-regulation
AGC_PKA_PRKACB_ST	Q01130	SRSF2	P22694	PRKACB	S134	S132R	132	Missense	proximal	-2	no	2.934	3.577	EPSD	COSMIC	2.323	Up-regulation
AGC_PKA_PRKACB_ST	Q01130	SRSF2	P22694	PRKACB	S134	S140N	140	Missense	distal	6	no	2.934	2.946	EPSD	COSMIC	2.323	Up-regulation
AGC_PKA_PRKACB_ST	Q01130	SRSF2	P22694	PRKACB	S134	R137T	137	Missense	distal	3	no	2.934	2.880	EPSD	COSMIC	2.323	Down-regulation
AGC_PKA_PRKACB_ST	Q01130	SRSF2	P22694	PRKACB	S134	R127C	127	Missense	distal	-7	no	2.934	2.703	EPSD	COSMIC	2.323	Down-regulation
AGC_PKA_PRKACB_ST	Q01130	SRSF2	P22694	PRKACB	S136	S130F	130	Missense	distal	-6	no	3.388	3.394	EPSD	COSMIC	2.323	Up-regulation
AGC_PKA_PRKACB_ST	Q01130	SRSF2	P22694	PRKACB	S136	S132R	132	Missense	distal	-4	no	3.388	3.433	EPSD	COSMIC	2.323	Up-regulation
AGC_PKA_PRKACB_ST	Q01130	SRSF2	P22694	PRKACB	S136	S140N	140	Missense	distal	4	no	3.388	3.390	EPSD	COSMIC	2.323	Up-regulation
AGC_PKA_PRKACB_ST	Q01130	SRSF2	P22694	PRKACB	S136	R137T	137	Missense	proximal	1	no	3.388	3.612	EPSD	COSMIC	2.323	Up-regulation
AGC_PKA_PRKACB_ST	Q01130	SRSF2	P22694	PRKACB	S142	S140N	140	Missense	proximal	-2	no	2.123	2.326	EPSD	COSMIC	2.323	Gain
AGC_PKA_PRKACB_ST	Q01130	SRSF2	P22694	PRKACB	T153	S157T	157	Missense	distal	4	no	2.409	2.412	EPSD	COSMIC	2.323	Up-regulation
AGC_PKA_PRKACB_ST	Q01130	SRSF2	P22694	PRKACB	T153	S159Y	159	Missense	distal	6	no	2.409	2.419	EPSD	COSMIC	2.323	Up-regulation
AGC_PKA_PRKACB_ST	Q01130	SRSF2	P22694	PRKACB	T153	S157F	157	Missense	distal	4	no	2.409	2.405	EPSD	COSMIC	2.323	Down-regulation
AGC_PKA_PRKACB_ST	Q01130	SRSF2	P22694	PRKACB	T153	R152S	152	Missense	proximal	-1	no	2.409	2.449	EPSD	COSMIC	2.323	Up-regulation
AGC_PKA_PRKACB_ST	Q01130	SRSF2	P22694	PRKACB	T153	T153A	153	Missense	central	0	yes	2.409	0.000	EPSD	COSMIC	2.323	Loss
AGC_PKA_PRKACB_ST	Q01130	SRSF2	P22694	PRKACB	T153	S147W	147	Missense	distal	-6	no	2.409	2.422	EPSD	COSMIC	2.323	Up-regulation
AGC_PKA_PRKACB_ST	Q01130	SRSF2	P22694	PRKACB	T153	R150W	150	Missense	distal	-3	no	2.409	0.308	EPSD	COSMIC	2.323	Loss
AGC_PKA_PRKACB_ST	Q01130	SRSF2	P22694	PRKACB	T153	S151P	151	Missense	proximal	-2	no	2.409	2.571	EPSD	COSMIC	2.323	Up-regulation
AGC_PKA_PRKACB_ST	Q01130	SRSF2	P22694	PRKACB	S171	S171Y	171	Missense	central	0	yes	2.390	0.000	EPSD;PhosphoSitePlus	COSMIC	2.323	Loss
AGC_PKA_PRKACB_ST	Q01130	SRSF2	P22694	PRKACB	S171	A166S	166	Missense	distal	-5	no	2.390	2.186	EPSD;PhosphoSitePlus	COSMIC	2.323	Loss
AGC_PKA_PRKACB_ST	Q01130	SRSF2	P22694	PRKACB	S171	S173F	173	Missense	proximal	2	no	2.390	2.393	EPSD;PhosphoSitePlus	COSMIC	2.323	Up-regulation
AGC_PKA_PRKACB_ST	Q01130	SRSF2	P22694	PRKACB	S171	S169T	169	Missense	proximal	-2	no	2.390	2.559	EPSD;PhosphoSitePlus	COSMIC	2.323	Up-regulation
AGC_PKA_PRKACB_ST	Q01130	SRSF2	P22694	PRKACB	S171	K172R	172	Missense	proximal	1	no	2.390	1.798	EPSD;PhosphoSitePlus	COSMIC	2.323	Loss
AGC_PKA_PRKACB_ST	Q01130	SRSF2	P22694	PRKACB	S171	S169F	169	Missense	proximal	-2	no	2.390	2.520	EPSD;PhosphoSitePlus	COSMIC;GDSC;CCLE	2.323	Up-regulation
AGC_PKA_PRKACB_ST	Q01130	SRSF2	P22694	PRKACB	S183	S179F	179	Missense	distal	-4	no	3.859	3.875	EPSD	COSMIC	2.323	Up-regulation
AGC_PKA_PRKACB_ST	Q01130	SRSF2	P22694	PRKACB	S183	S183Y	183	Missense	central	0	yes	3.859	0.000	EPSD	COSMIC	2.323	Loss
AGC_PKA_PRKACB_ST	Q01130	SRSF2	P22694	PRKACB	S185	S179F	179	Missense	distal	-6	no	4.744	4.750	EPSD	COSMIC	2.323	Up-regulation
AGC_PKA_PRKACB_ST	Q01130	SRSF2	P22694	PRKACB	S185	S183Y	183	Missense	proximal	-2	no	4.744	4.798	EPSD	COSMIC	2.323	Up-regulation
AGC_PKA_PRKACB_ST	Q01130	SRSF2	P22694	PRKACB	S191	V195M	195	Missense	distal	4	no	3.821	3.818	EPSD	COSMIC	2.323	Down-regulation
AGC_PKA_PRKACB_ST	Q01130	SRSF2	P22694	PRKACB	S191	K197N	197	Missense	distal	6	no	3.821	3.794	EPSD	COSMIC	2.323	Down-regulation
AGC_PKA_PRKACB_ST	Q01130	SRSF2	P22694	PRKACB	S191	S196F	196	Missense	distal	5	no	3.821	3.822	EPSD	COSMIC	2.323	Up-regulation
AGC_PKA_PRKACB_ST	Q01130	SRSF2	P22694	PRKACB	S191	V195L	195	Missense	distal	4	no	3.821	3.817	EPSD	COSMIC	2.323	Down-regulation
AGC_PKA_PRKACB_ST	Q01130	SRSF2	P22694	PRKACB	S200	V195M	195	Missense	distal	-5	no	3.925	4.020	EPSD	COSMIC	2.323	Up-regulation
AGC_PKA_PRKACB_ST	Q01130	SRSF2	P22694	PRKACB	S200	S204L	204	Missense	distal	4	no	3.925	3.926	EPSD	COSMIC	2.323	Up-regulation
AGC_PKA_PRKACB_ST	Q01130	SRSF2	P22694	PRKACB	S200	K197N	197	Missense	distal	-3	no	3.925	1.824	EPSD	COSMIC	2.323	Loss
AGC_PKA_PRKACB_ST	Q01130	SRSF2	P22694	PRKACB	S200	S196F	196	Missense	distal	-4	no	3.925	3.942	EPSD	COSMIC	2.323	Up-regulation
AGC_PKA_PRKACB_ST	Q01130	SRSF2	P22694	PRKACB	S200	V195L	195	Missense	distal	-5	no	3.925	3.912	EPSD	COSMIC	2.323	Down-regulation
AGC_PKA_PRKACB_ST	Q01130	SRSF2	P22694	PRKACB	S200	S206A	206	Missense	distal	6	no	3.925	3.929	EPSD	COSMIC	2.323	Up-regulation
AGC_PKA_PRKACB_ST	P08138	NGFR	P22694	PRKACB	S303	V309M	309	Missense	distal	6	no	7.142	7.123	PhosphoSitePlus	COSMIC	2.323	Down-regulation
AGC_PKA_PRKACB_ST	P08138	NGFR	P22694	PRKACB	S303	D304N	304	Missense	proximal	1	no	7.142	6.898	PhosphoSitePlus	COSMIC	2.323	Down-regulation
CK1_CK1_CK1-G_CSNK1G1_ST	P25054	APC	Q9HCP0	CSNK1G1	S95	S95F	95	Missense	central	0	yes	2.401	0.000	EPSD	COSMIC	1.928	Loss
CK1_CK1_CK1-G_CSNK1G1_ST	P25054	APC	Q9HCP0	CSNK1G1	S95	R94H	94	Missense	proximal	-1	no	2.401	2.419	EPSD	COSMIC	1.928	Up-regulation
CK1_CK1_CK1-G_CSNK1G1_ST	P25054	APC	Q9HCP0	CSNK1G1	S95	R99W	99	Missense	distal	4	no	2.401	2.299	EPSD	COSMIC	1.928	Down-regulation
CK1_CK1_CK1-G_CSNK1G1_ST	P25054	APC	Q9HCP0	CSNK1G1	S95	R94C	94	Missense	proximal	-1	no	2.401	2.412	EPSD	COSMIC;GDSC;CCLE	1.928	Up-regulation
CK1_CK1_CK1-G_CSNK1G1_ST	P25054	APC	Q9HCP0	CSNK1G1	S95	K90N	90	Missense	distal	-5	no	2.401	2.377	EPSD	COSMIC	1.928	Down-regulation
CK1_CK1_CK1-G_CSNK1G1_ST	P25054	APC	Q9HCP0	CSNK1G1	S95	R88W	88	Missense	distal	-7	no	2.401	2.390	EPSD	COSMIC	1.928	Down-regulation
CK1_CK1_CK1-G_CSNK1G1_ST	P25054	APC	Q9HCP0	CSNK1G1	S95	S89L	89	Missense	distal	-6	no	2.401	1.604	EPSD	COSMIC	1.928	Loss
CK1_CK1_CK1-G_CSNK1G1_ST	P25054	APC	Q9HCP0	CSNK1G1	S98	S95F	95	Missense	distal	-3	no	2.046	1.589	EPSD	COSMIC	1.928	Loss
CK1_CK1_CK1-G_CSNK1G1_ST	P25054	APC	Q9HCP0	CSNK1G1	S98	R94H	94	Missense	distal	-4	no	2.046	2.047	EPSD	COSMIC	1.928	Up-regulation
CK1_CK1_CK1-G_CSNK1G1_ST	P25054	APC	Q9HCP0	CSNK1G1	S98	R99W	99	Missense	proximal	1	no	2.046	2.070	EPSD	COSMIC	1.928	Up-regulation
CK1_CK1_CK1-G_CSNK1G1_ST	P25054	APC	Q9HCP0	CSNK1G1	S98	R94C	94	Missense	distal	-4	no	2.046	2.048	EPSD	COSMIC;GDSC;CCLE	1.928	Up-regulation
CK1_CK1_CK1-G_CSNK1G1_ST	P25054	APC	Q9HCP0	CSNK1G1	S98	S105G	105	Missense	distal	7	no	2.046	2.053	EPSD	COSMIC	1.928	Up-regulation
CK1_CK1_CK1-G_CSNK1G1_ST	P25054	APC	Q9HCP0	CSNK1G1	S299	T305R	305	Missense	distal	6	no	1.952	2.019	EPSD	COSMIC	1.928	Up-regulation
CK1_CK1_CK1-G_CSNK1G1_ST	P25054	APC	Q9HCP0	CSNK1G1	S299	R303K	303	Missense	distal	4	no	1.952	1.883	EPSD	COSMIC	1.928	Loss
CK1_CK1_CK1-G_CSNK1G1_ST	P25054	APC	Q9HCP0	CSNK1G1	S299	P301L	301	Missense	proximal	2	no	1.952	1.804	EPSD	COSMIC	1.928	Loss
CK1_CK1_CK1-G_CSNK1G1_ST	P25054	APC	Q9HCP0	CSNK1G1	S299	L292F	292	Missense	distal	-7	no	1.952	1.849	EPSD	COSMIC	1.928	Loss
CK1_CK1_CK1-G_CSNK1G1_ST	P25054	APC	Q9HCP0	CSNK1G1	S299	T297A	297	Missense	proximal	-2	no	1.952	1.933	EPSD	COSMIC	1.928	Down-regulation
CK1_CK1_CK1-G_CSNK1G1_ST	P25054	APC	Q9HCP0	CSNK1G1	S559	E565V	565	Missense	distal	6	no	2.048	2.178	EPSD	COSMIC	1.928	Up-regulation
CK1_CK1_CK1-G_CSNK1G1_ST	P25054	APC	Q9HCP0	CSNK1G1	S559	K560E	560	Missense	proximal	1	no	2.048	2.069	EPSD	COSMIC	1.928	Up-regulation
CK1_CK1_CK1-G_CSNK1G1_ST	P25054	APC	Q9HCP0	CSNK1G1	S751	P745R	745	Missense	distal	-6	no	1.836	1.947	EPSD	COSMIC	1.928	Gain
CK1_CK1_CK1-G_CSNK1G1_ST	P25054	APC	Q9HCP0	CSNK1G1	S780	L779V	779	Missense	proximal	-1	no	2.279	2.267	EPSD	COSMIC	1.928	Down-regulation
CK1_CK1_CK1-G_CSNK1G1_ST	P25054	APC	Q9HCP0	CSNK1G1	S780	N778D	778	Missense	proximal	-2	no	2.279	2.313	EPSD	COSMIC	1.928	Up-regulation
CK1_CK1_CK1-G_CSNK1G1_ST	P25054	APC	Q9HCP0	CSNK1G1	S780	K782E	782	Missense	proximal	2	no	2.279	2.261	EPSD	COSMIC	1.928	Down-regulation
CK1_CK1_CK1-G_CSNK1G1_ST	P25054	APC	Q9HCP0	CSNK1G1	S780	D777Y	777	Missense	distal	-3	no	2.279	1.931	EPSD	COSMIC	1.928	Down-regulation
CK1_CK1_CK1-G_CSNK1G1_ST	P25054	APC	Q9HCP0	CSNK1G1	S780	P781L	781	Missense	proximal	1	no	2.279	2.622	EPSD	COSMIC	1.928	Up-regulation
CK1_CK1_CK1-G_CSNK1G1_ST	P25054	APC	Q9HCP0	CSNK1G1	S780	N775S	775	Missense	distal	-5	no	2.279	2.193	EPSD	COSMIC	1.928	Down-regulation
CK1_CK1_CK1-G_CSNK1G1_ST	P25054	APC	Q9HCP0	CSNK1G1	S780	L779S	779	Missense	proximal	-1	no	2.279	2.343	EPSD	COSMIC	1.928	Up-regulation
CK1_CK1_CK1-G_CSNK1G1_ST	P25054	APC	Q9HCP0	CSNK1G1	S780	H785D	785	Missense	distal	5	no	2.279	2.281	EPSD	COSMIC	1.928	Up-regulation
CK1_CK1_CK1-G_CSNK1G1_ST	P25054	APC	Q9HCP0	CSNK1G1	T867	E868K	868	Missense	proximal	1	no	1.988	1.968	EPSD	COSMIC	1.928	Down-regulation
CK1_CK1_CK1-G_CSNK1G1_ST	P25054	APC	Q9HCP0	CSNK1G1	T867	P870S	870	Missense	distal	3	no	1.988	2.102	EPSD	COSMIC	1.928	Up-regulation
CK1_CK1_CK1-G_CSNK1G1_ST	P25054	APC	Q9HCP0	CSNK1G1	T867	P870L	870	Missense	distal	3	no	1.988	2.009	EPSD	COSMIC	1.928	Up-regulation
CK1_CK1_CK1-G_CSNK1G1_ST	P25054	APC	Q9HCP0	CSNK1G1	T867	N862K	862	Missense	distal	-5	no	1.988	2.011	EPSD	COSMIC;GDSC	1.928	Up-regulation
CK1_CK1_CK1-G_CSNK1G1_ST	P25054	APC	Q9HCP0	CSNK1G1	T867	A866V	866	Missense	proximal	-1	no	1.988	2.007	EPSD	COSMIC	1.928	Up-regulation
CK1_CK1_CK1-G_CSNK1G1_ST	P25054	APC	Q9HCP0	CSNK1G1	T867	G861C	861	Missense	distal	-6	no	1.988	1.373	EPSD	COSMIC	1.928	Loss
CK1_CK1_CK1-G_CSNK1G1_ST	P25054	APC	Q9HCP0	CSNK1G1	S874	E868K	868	Missense	distal	-6	no	2.555	2.410	EPSD	COSMIC	1.928	Down-regulation
CK1_CK1_CK1-G_CSNK1G1_ST	P25054	APC	Q9HCP0	CSNK1G1	S874	K875R	875	Missense	proximal	1	no	2.555	2.537	EPSD	COSMIC	1.928	Down-regulation
CK1_CK1_CK1-G_CSNK1G1_ST	P25054	APC	Q9HCP0	CSNK1G1	S874	P870S	870	Missense	distal	-4	no	2.555	2.616	EPSD	COSMIC	1.928	Up-regulation
CK1_CK1_CK1-G_CSNK1G1_ST	P25054	APC	Q9HCP0	CSNK1G1	S874	P870L	870	Missense	distal	-4	no	2.555	2.609	EPSD	COSMIC	1.928	Up-regulation
CK1_CK1_CK1-G_CSNK1G1_ST	P25054	APC	Q9HCP0	CSNK1G1	S874	I880T	880	Missense	distal	6	no	2.555	2.268	EPSD	COSMIC	1.928	Down-regulation
CK1_CK1_CK1-G_CSNK1G1_ST	P25054	APC	Q9HCP0	CSNK1G1	S874	I880F	880	Missense	distal	6	no	2.555	2.381	EPSD	COSMIC	1.928	Down-regulation
CK1_CK1_CK1-G_CSNK1G1_ST	P25054	APC	Q9HCP0	CSNK1G1	T883	I880T	880	Missense	distal	-3	no	1.640	2.000	EPSD	COSMIC	1.928	Gain
CK1_CK1_CK1-G_CSNK1G1_ST	P25054	APC	Q9HCP0	CSNK1G1	S963	S963I	963	Missense	central	0	yes	3.170	0.000	EPSD	COSMIC	1.928	Loss
CK1_CK1_CK1-G_CSNK1G1_ST	P25054	APC	Q9HCP0	CSNK1G1	S963	Y956H	956	Missense	distal	-7	no	3.170	3.201	EPSD	COSMIC	1.928	Up-regulation
CK1_CK1_CK1-G_CSNK1G1_ST	P25054	APC	Q9HCP0	CSNK1G1	S963	S966R	966	Missense	distal	3	no	3.170	3.079	EPSD	COSMIC	1.928	Down-regulation
CK1_CK1_CK1-G_CSNK1G1_ST	P25054	APC	Q9HCP0	CSNK1G1	S963	Y956C	956	Missense	distal	-7	no	3.170	3.214	EPSD	COSMIC	1.928	Up-regulation
CK1_CK1_CK1-G_CSNK1G1_ST	P25054	APC	Q9HCP0	CSNK1G1	S1180	D1174G	1174	Missense	distal	-6	no	2.050	2.091	EPSD	COSMIC	1.928	Up-regulation
CK1_CK1_CK1-G_CSNK1G1_ST	P25054	APC	Q9HCP0	CSNK1G1	S1180	I1177M	1177	Missense	distal	-3	no	2.050	2.127	EPSD	COSMIC;GDSC;CCLE	1.928	Up-regulation
CK1_CK1_CK1-G_CSNK1G1_ST	P25054	APC	Q9HCP0	CSNK1G1	S1180	T1185K	1185	Missense	distal	5	no	2.050	2.047	EPSD	COSMIC	1.928	Down-regulation
CK1_CK1_CK1-G_CSNK1G1_ST	P25054	APC	Q9HCP0	CSNK1G1	S1180	D1174N	1174	Missense	distal	-6	no	2.050	1.639	EPSD	COSMIC	1.928	Loss
CK1_CK1_CK1-G_CSNK1G1_ST	P25054	APC	Q9HCP0	CSNK1G1	S1180	P1176L	1176	Missense	distal	-4	no	2.050	2.103	EPSD	COSMIC	1.928	Up-regulation
CK1_CK1_CK1-G_CSNK1G1_ST	P25054	APC	Q9HCP0	CSNK1G1	S1180	I1177V	1177	Missense	distal	-3	no	2.050	2.226	EPSD	COSMIC	1.928	Up-regulation
CK1_CK1_CK1-G_CSNK1G1_ST	P25054	APC	Q9HCP0	CSNK1G1	S1180	Q1175K	1175	Missense	distal	-5	no	2.050	2.045	EPSD	COSMIC	1.928	Down-regulation
CK1_CK1_CK1-G_CSNK1G1_ST	P25054	APC	Q9HCP0	CSNK1G1	S1371	A1366G	1366	Missense	distal	-5	no	1.970	1.879	EPSD	COSMIC	1.928	Loss
CK1_CK1_CK1-G_CSNK1G1_ST	P25054	APC	Q9HCP0	CSNK1G1	S1371	P1373S	1373	Missense	proximal	2	no	1.970	1.767	EPSD	COSMIC	1.928	Loss
CK1_CK1_CK1-G_CSNK1G1_ST	P25054	APC	Q9HCP0	CSNK1G1	S1371	T1368I	1368	Missense	distal	-3	no	1.970	1.610	EPSD	COSMIC	1.928	Loss
CK1_CK1_CK1-G_CSNK1G1_ST	P25054	APC	Q9HCP0	CSNK1G1	S1371	S1364R	1364	Missense	distal	-7	no	1.970	1.813	EPSD	COSMIC	1.928	Loss
CK1_CK1_CK1-G_CSNK1G1_ST	P25054	APC	Q9HCP0	CSNK1G1	S1371	P1369H	1369	Missense	proximal	-2	no	1.970	2.007	EPSD	COSMIC	1.928	Up-regulation
CK1_CK1_CK1-G_CSNK1G1_ST	P25054	APC	Q9HCP0	CSNK1G1	S1371	E1374K	1374	Missense	distal	3	no	1.970	1.956	EPSD	COSMIC	1.928	Down-regulation
CK1_CK1_CK1-G_CSNK1G1_ST	P25054	APC	Q9HCP0	CSNK1G1	S1371	Q1367R	1367	Missense	distal	-4	no	1.970	1.974	EPSD	COSMIC	1.928	Up-regulation
CK1_CK1_CK1-G_CSNK1G1_ST	P25054	APC	Q9HCP0	CSNK1G1	S1371	H1375Y	1375	Missense	distal	4	no	1.970	2.063	EPSD	COSMIC	1.928	Up-regulation
CK1_CK1_CK1-G_CSNK1G1_ST	P25054	APC	Q9HCP0	CSNK1G1	S1371	Q1367H	1367	Missense	distal	-4	no	1.970	1.975	EPSD	COSMIC	1.928	Up-regulation
CK1_CK1_CK1-G_CSNK1G1_ST	P25054	APC	Q9HCP0	CSNK1G1	S1371	P1373T	1373	Missense	proximal	2	no	1.970	1.932	EPSD	COSMIC	1.928	Down-regulation
CK1_CK1_CK1-G_CSNK1G1_ST	P25054	APC	Q9HCP0	CSNK1G1	S1371	P1373L	1373	Missense	proximal	2	no	1.970	1.823	EPSD	COSMIC	1.928	Loss
CK1_CK1_CK1-G_CSNK1G1_ST	P25054	APC	Q9HCP0	CSNK1G1	S1371	T1368S	1368	Missense	distal	-3	no	1.970	2.094	EPSD	COSMIC	1.928	Up-regulation
CK1_CK1_CK1-G_CSNK1G1_ST	P25054	APC	Q9HCP0	CSNK1G1	S1371	G1365D	1365	Missense	distal	-6	no	1.970	1.929	EPSD	COSMIC	1.928	Down-regulation
CK1_CK1_CK1-G_CSNK1G1_ST	P25054	APC	Q9HCP0	CSNK1G1	S1371	T1368K	1368	Missense	distal	-3	no	1.970	1.638	EPSD	COSMIC	1.928	Loss
CK1_CK1_CK1-G_CSNK1G1_ST	P25054	APC	Q9HCP0	CSNK1G1	T1445	P1439S	1439	Missense	distal	-6	no	1.482	2.514	EPSD	COSMIC	1.928	Gain
CK1_CK1_CK1-G_CSNK1G1_ST	P25054	APC	Q9HCP0	CSNK1G1	T1445	P1442S	1442	Missense	distal	-3	no	1.482	1.956	EPSD	COSMIC	1.928	Gain
CK1_CK1_CK1-G_CSNK1G1_ST	P25054	APC	Q9HCP0	CSNK1G1	S1503	P1497S	1497	Missense	distal	-6	no	1.443	2.476	EPSD	COSMIC	1.928	Gain
CK1_CK1_CK1-G_CSNK1G1_ST	P25054	APC	Q9HCP0	CSNK1G1	S1504	S1501A	1501	Missense	distal	-3	no	5.966	5.499	EPSD;PhosphoSitePlus	COSMIC	1.928	Down-regulation
CK1_CK1_CK1-G_CSNK1G1_ST	P25054	APC	Q9HCP0	CSNK1G1	S1504	P1497S	1497	Missense	distal	-7	no	5.966	6.128	EPSD;PhosphoSitePlus	COSMIC	1.928	Up-regulation
CK1_CK1_CK1-G_CSNK1G1_ST	P25054	APC	Q9HCP0	CSNK1G1	S1504	G1499R	1499	Missense	distal	-5	no	5.966	6.039	EPSD;PhosphoSitePlus	COSMIC	1.928	Up-regulation
CK1_CK1_CK1-G_CSNK1G1_ST	P25054	APC	Q9HCP0	CSNK1G1	S1504	D1498N	1498	Missense	distal	-6	no	5.966	5.555	EPSD;PhosphoSitePlus	COSMIC	1.928	Down-regulation
CK1_CK1_CK1-G_CSNK1G1_ST	P25054	APC	Q9HCP0	CSNK1G1	S1504	S1504F	1504	Missense	central	0	yes	5.966	0.000	EPSD;PhosphoSitePlus	COSMIC	1.928	Loss
CK1_CK1_CK1-G_CSNK1G1_ST	P25054	APC	Q9HCP0	CSNK1G1	S1504	A1508V	1508	Missense	distal	4	no	5.966	5.933	EPSD;PhosphoSitePlus	COSMIC	1.928	Down-regulation
CK1_CK1_CK1-G_CSNK1G1_ST	P25054	APC	Q9HCP0	CSNK1G1	S1504	P1497L	1497	Missense	distal	-7	no	5.966	5.982	EPSD;PhosphoSitePlus	COSMIC	1.928	Up-regulation
CK1_CK1_CK1-G_CSNK1G1_ST	P25054	APC	Q9HCP0	CSNK1G1	S1504	S1503L	1503	Missense	proximal	-1	no	5.966	5.902	EPSD;PhosphoSitePlus	COSMIC	1.928	Down-regulation
CK1_CK1_CK1-G_CSNK1G1_ST	P25054	APC	Q9HCP0	CSNK1G1	S1504	S1501F	1501	Missense	distal	-3	no	5.966	5.509	EPSD;PhosphoSitePlus	COSMIC	1.928	Down-regulation
CK1_CK1_CK1-G_CSNK1G1_ST	P25054	APC	Q9HCP0	CSNK1G1	S1505	S1501A	1501	Missense	distal	-4	no	5.317	5.292	EPSD;PhosphoSitePlus	COSMIC	1.928	Down-regulation
CK1_CK1_CK1-G_CSNK1G1_ST	P25054	APC	Q9HCP0	CSNK1G1	S1505	G1499R	1499	Missense	distal	-6	no	5.317	4.563	EPSD;PhosphoSitePlus	COSMIC	1.928	Down-regulation
CK1_CK1_CK1-G_CSNK1G1_ST	P25054	APC	Q9HCP0	CSNK1G1	S1505	D1512N	1512	Missense	distal	7	no	5.317	5.321	EPSD;PhosphoSitePlus	COSMIC	1.928	Up-regulation
CK1_CK1_CK1-G_CSNK1G1_ST	P25054	APC	Q9HCP0	CSNK1G1	S1505	D1498N	1498	Missense	distal	-7	no	5.317	5.097	EPSD;PhosphoSitePlus	COSMIC	1.928	Down-regulation
CK1_CK1_CK1-G_CSNK1G1_ST	P25054	APC	Q9HCP0	CSNK1G1	S1505	S1504F	1504	Missense	proximal	-1	no	5.317	5.185	EPSD;PhosphoSitePlus	COSMIC	1.928	Down-regulation
CK1_CK1_CK1-G_CSNK1G1_ST	P25054	APC	Q9HCP0	CSNK1G1	S1505	A1508V	1508	Missense	distal	3	no	5.317	5.332	EPSD;PhosphoSitePlus	COSMIC	1.928	Up-regulation
CK1_CK1_CK1-G_CSNK1G1_ST	P25054	APC	Q9HCP0	CSNK1G1	S1505	S1503L	1503	Missense	proximal	-2	no	5.317	5.304	EPSD;PhosphoSitePlus	COSMIC	1.928	Down-regulation
CK1_CK1_CK1-G_CSNK1G1_ST	P25054	APC	Q9HCP0	CSNK1G1	S1505	S1501F	1501	Missense	distal	-4	no	5.317	5.283	EPSD;PhosphoSitePlus	COSMIC	1.928	Down-regulation
CK1_CK1_CK1-G_CSNK1G1_ST	P25054	APC	Q9HCP0	CSNK1G1	S1505	D1512V	1512	Missense	distal	7	no	5.317	5.328	EPSD;PhosphoSitePlus	COSMIC	1.928	Up-regulation
CK1_CK1_CK1-G_CSNK1G1_ST	P25054	APC	Q9HCP0	CSNK1G1	S1507	S1501A	1501	Missense	distal	-6	no	5.668	4.793	PhosphoSitePlus;EPSD	COSMIC	1.928	Down-regulation
CK1_CK1_CK1-G_CSNK1G1_ST	P25054	APC	Q9HCP0	CSNK1G1	S1507	D1512N	1512	Missense	distal	5	no	5.668	5.670	PhosphoSitePlus;EPSD	COSMIC	1.928	Up-regulation
CK1_CK1_CK1-G_CSNK1G1_ST	P25054	APC	Q9HCP0	CSNK1G1	S1507	S1504F	1504	Missense	distal	-3	no	5.668	5.212	PhosphoSitePlus;EPSD	COSMIC	1.928	Down-regulation
CK1_CK1_CK1-G_CSNK1G1_ST	P25054	APC	Q9HCP0	CSNK1G1	S1507	A1508V	1508	Missense	proximal	1	no	5.668	5.775	PhosphoSitePlus;EPSD	COSMIC	1.928	Up-regulation
CK1_CK1_CK1-G_CSNK1G1_ST	P25054	APC	Q9HCP0	CSNK1G1	S1507	P1514S	1514	Missense	distal	7	no	5.668	5.662	PhosphoSitePlus;EPSD	COSMIC	1.928	Down-regulation
CK1_CK1_CK1-G_CSNK1G1_ST	P25054	APC	Q9HCP0	CSNK1G1	S1507	S1503L	1503	Missense	distal	-4	no	5.668	5.662	PhosphoSitePlus;EPSD	COSMIC	1.928	Down-regulation
CK1_CK1_CK1-G_CSNK1G1_ST	P25054	APC	Q9HCP0	CSNK1G1	S1507	S1501F	1501	Missense	distal	-6	no	5.668	4.751	PhosphoSitePlus;EPSD	COSMIC	1.928	Down-regulation
CK1_CK1_CK1-G_CSNK1G1_ST	P25054	APC	Q9HCP0	CSNK1G1	S1510	P1514L	1514	Missense	distal	4	no	5.287	5.485	EPSD;PhosphoSitePlus	COSMIC	1.928	Up-regulation
CK1_CK1_CK1-G_CSNK1G1_ST	P25054	APC	Q9HCP0	CSNK1G1	S1510	D1512N	1512	Missense	proximal	2	no	5.287	5.242	EPSD;PhosphoSitePlus	COSMIC	1.928	Down-regulation
CK1_CK1_CK1-G_CSNK1G1_ST	P25054	APC	Q9HCP0	CSNK1G1	S1510	S1504F	1504	Missense	distal	-6	no	5.287	4.370	EPSD;PhosphoSitePlus	COSMIC	1.928	Down-regulation
CK1_CK1_CK1-G_CSNK1G1_ST	P25054	APC	Q9HCP0	CSNK1G1	S1510	A1508V	1508	Missense	proximal	-2	no	5.287	5.306	EPSD;PhosphoSitePlus	COSMIC	1.928	Up-regulation
CK1_CK1_CK1-G_CSNK1G1_ST	P25054	APC	Q9HCP0	CSNK1G1	S1510	P1514S	1514	Missense	distal	4	no	5.287	5.341	EPSD;PhosphoSitePlus	COSMIC	1.928	Up-regulation
CK1_CK1_CK1-G_CSNK1G1_ST	P25054	APC	Q9HCP0	CSNK1G1	S1510	I1516V	1516	Missense	distal	6	no	5.287	5.238	EPSD;PhosphoSitePlus	COSMIC	1.928	Down-regulation
CK1_CK1_CK1-G_CSNK1G1_ST	P25054	APC	Q9HCP0	CSNK1G1	S1510	S1503L	1503	Missense	distal	-7	no	5.287	5.142	EPSD;PhosphoSitePlus	COSMIC	1.928	Down-regulation
CK1_CK1_CK1-G_CSNK1G1_ST	P25054	APC	Q9HCP0	CSNK1G1	S1510	F1515L	1515	Missense	distal	5	no	5.287	5.290	EPSD;PhosphoSitePlus	COSMIC	1.928	Up-regulation
CK1_CK1_CK1-G_CSNK1G1_ST	P25054	APC	Q9HCP0	CSNK1G1	S1510	D1512V	1512	Missense	proximal	2	no	5.287	5.201	EPSD;PhosphoSitePlus	COSMIC	1.928	Down-regulation
CK1_CK1_CK1-G_CSNK1G1_ST	P25054	APC	Q9HCP0	CSNK1G1	S1539	T1537K	1537	Missense	proximal	-2	no	2.392	2.359	EPSD	COSMIC	1.928	Down-regulation
CK1_CK1_CK1-G_CSNK1G1_ST	P25054	APC	Q9HCP0	CSNK1G1	S1539	E1536K	1536	Missense	distal	-3	no	2.392	2.339	EPSD	COSMIC	1.928	Down-regulation
CK1_CK1_CK1-G_CSNK1G1_ST	P25054	APC	Q9HCP0	CSNK1G1	S1539	S1545L	1545	Missense	distal	6	no	2.392	2.572	EPSD	COSMIC;GDSC;CCLE	1.928	Up-regulation
CK1_CK1_CK1-G_CSNK1G1_ST	P25054	APC	Q9HCP0	CSNK1G1	S1539	G1534V	1534	Missense	distal	-5	no	2.392	2.475	EPSD	COSMIC	1.928	Up-regulation
CK1_CK1_CK1-G_CSNK1G1_ST	P25054	APC	Q9HCP0	CSNK1G1	S1539	G1534R	1534	Missense	distal	-5	no	2.392	2.465	EPSD	COSMIC	1.928	Up-regulation
CK1_CK1_CK1-G_CSNK1G1_ST	P25054	APC	Q9HCP0	CSNK1G1	S1539	G1534E	1534	Missense	distal	-5	no	2.392	2.460	EPSD	COSMIC	1.928	Up-regulation
CK1_CK1_CK1-G_CSNK1G1_ST	P25054	APC	Q9HCP0	CSNK1G1	S1539	N1533D	1533	Missense	distal	-6	no	2.392	2.803	EPSD	COSMIC	1.928	Up-regulation
CK1_CK1_CK1-G_CSNK1G1_ST	P25054	APC	Q9HCP0	CSNK1G1	S1539	E1544K	1544	Missense	distal	5	no	2.392	2.391	EPSD	COSMIC	1.928	Down-regulation
CK1_CK1_CK1-G_CSNK1G1_ST	P25054	APC	Q9HCP0	CSNK1G1	S1559	A1553G	1553	Missense	distal	-6	no	1.294	2.002	EPSD	COSMIC	1.928	Gain
CK1_CK1_CK1-G_CSNK1G1_ST	P25054	APC	Q9HCP0	CSNK1G1	S1610	P1604S	1604	Missense	distal	-6	no	1.394	2.427	EPSD	COSMIC	1.928	Gain
CK1_CK1_CK1-G_CSNK1G1_ST	P25054	APC	Q9HCP0	CSNK1G1	S1652	S1652P	1652	Missense	central	0	yes	2.224	0.000	EPSD	COSMIC	1.928	Loss
CK1_CK1_CK1-G_CSNK1G1_ST	P25054	APC	Q9HCP0	CSNK1G1	S1652	S1656F	1656	Missense	distal	4	no	2.224	2.009	EPSD	COSMIC	1.928	Down-regulation
CK1_CK1_CK1-G_CSNK1G1_ST	P25054	APC	Q9HCP0	CSNK1G1	S1652	P1648A	1648	Missense	distal	-4	no	2.224	2.259	EPSD	COSMIC	1.928	Up-regulation
CK1_CK1_CK1-G_CSNK1G1_ST	P25054	APC	Q9HCP0	CSNK1G1	S1652	S1656Y	1656	Missense	distal	4	no	2.224	2.175	EPSD	COSMIC;GDSC;CCLE	1.928	Down-regulation
CK1_CK1_CK1-G_CSNK1G1_ST	P25054	APC	Q9HCP0	CSNK1G1	S1652	E1645Q	1645	Missense	distal	-7	no	2.224	2.207	EPSD	COSMIC	1.928	Down-regulation
CK1_CK1_CK1-G_CSNK1G1_ST	P25054	APC	Q9HCP0	CSNK1G1	S1652	L1657R	1657	Missense	distal	5	no	2.224	2.219	EPSD	COSMIC	1.928	Down-regulation
CK1_CK1_CK1-G_CSNK1G1_ST	P25054	APC	Q9HCP0	CSNK1G1	S1652	S1658R	1658	Missense	distal	6	no	2.224	2.097	EPSD	COSMIC	1.928	Down-regulation
CK1_CK1_CK1-G_CSNK1G1_ST	P25054	APC	Q9HCP0	CSNK1G1	T1655	S1652P	1652	Missense	distal	-3	no	2.326	1.852	EPSD	COSMIC	1.928	Loss
CK1_CK1_CK1-G_CSNK1G1_ST	P25054	APC	Q9HCP0	CSNK1G1	T1655	S1656F	1656	Missense	proximal	1	no	2.326	2.226	EPSD	COSMIC	1.928	Down-regulation
CK1_CK1_CK1-G_CSNK1G1_ST	P25054	APC	Q9HCP0	CSNK1G1	T1655	L1660P	1660	Missense	distal	5	no	2.326	2.322	EPSD	COSMIC	1.928	Down-regulation
CK1_CK1_CK1-G_CSNK1G1_ST	P25054	APC	Q9HCP0	CSNK1G1	T1655	P1648A	1648	Missense	distal	-7	no	2.326	2.252	EPSD	COSMIC	1.928	Down-regulation
CK1_CK1_CK1-G_CSNK1G1_ST	P25054	APC	Q9HCP0	CSNK1G1	T1655	S1656Y	1656	Missense	proximal	1	no	2.326	2.267	EPSD	COSMIC;GDSC;CCLE	1.928	Down-regulation
CK1_CK1_CK1-G_CSNK1G1_ST	P25054	APC	Q9HCP0	CSNK1G1	T1655	L1657R	1657	Missense	proximal	2	no	2.326	2.407	EPSD	COSMIC	1.928	Up-regulation
CK1_CK1_CK1-G_CSNK1G1_ST	P25054	APC	Q9HCP0	CSNK1G1	T1655	S1658R	1658	Missense	distal	3	no	2.326	2.236	EPSD	COSMIC	1.928	Down-regulation
CK1_CK1_CK1-G_CSNK1G1_ST	P25054	APC	Q9HCP0	CSNK1G1	S1658	S1652P	1652	Missense	distal	-6	no	2.003	0.971	EPSD	COSMIC	1.928	Loss
CK1_CK1_CK1-G_CSNK1G1_ST	P25054	APC	Q9HCP0	CSNK1G1	S1658	S1656F	1656	Missense	proximal	-2	no	2.003	1.967	EPSD	COSMIC	1.928	Down-regulation
CK1_CK1_CK1-G_CSNK1G1_ST	P25054	APC	Q9HCP0	CSNK1G1	S1658	L1660P	1660	Missense	proximal	2	no	2.003	2.150	EPSD	COSMIC	1.928	Up-regulation
CK1_CK1_CK1-G_CSNK1G1_ST	P25054	APC	Q9HCP0	CSNK1G1	S1658	E1663K	1663	Missense	distal	5	no	2.003	2.002	EPSD	COSMIC	1.928	Down-regulation
CK1_CK1_CK1-G_CSNK1G1_ST	P25054	APC	Q9HCP0	CSNK1G1	S1658	S1656Y	1656	Missense	proximal	-2	no	2.003	1.977	EPSD	COSMIC;GDSC;CCLE	1.928	Down-regulation
CK1_CK1_CK1-G_CSNK1G1_ST	P25054	APC	Q9HCP0	CSNK1G1	S1658	S1664F	1664	Missense	distal	6	no	2.003	1.922	EPSD	COSMIC	1.928	Loss
CK1_CK1_CK1-G_CSNK1G1_ST	P25054	APC	Q9HCP0	CSNK1G1	S1658	L1657R	1657	Missense	proximal	-1	no	2.003	1.916	EPSD	COSMIC	1.928	Loss
CK1_CK1_CK1-G_CSNK1G1_ST	P25054	APC	Q9HCP0	CSNK1G1	S1658	S1658R	1658	Missense	central	0	yes	2.003	0.000	EPSD	COSMIC	1.928	Loss
CK1_CK1_CK1-G_CSNK1G1_ST	P25054	APC	Q9HCP0	CSNK1G1	S1658	S1664Y	1664	Missense	distal	6	no	2.003	1.956	EPSD	COSMIC	1.928	Down-regulation
CK1_CK1_CK1-G_CSNK1G1_ST	P25054	APC	Q9HCP0	CSNK1G1	S1658	P1665T	1665	Missense	distal	7	no	2.003	2.005	EPSD	COSMIC	1.928	Up-regulation
CK1_CK1_CK1-G_CSNK1G1_ST	P25054	APC	Q9HCP0	CSNK1G1	T1661	P1666L	1666	Missense	distal	5	no	2.545	2.549	EPSD	COSMIC	1.928	Up-regulation
CK1_CK1_CK1-G_CSNK1G1_ST	P25054	APC	Q9HCP0	CSNK1G1	T1661	S1656F	1656	Missense	distal	-5	no	2.545	2.657	EPSD	COSMIC	1.928	Up-regulation
CK1_CK1_CK1-G_CSNK1G1_ST	P25054	APC	Q9HCP0	CSNK1G1	T1661	L1660P	1660	Missense	proximal	-1	no	2.545	2.418	EPSD	COSMIC	1.928	Down-regulation
CK1_CK1_CK1-G_CSNK1G1_ST	P25054	APC	Q9HCP0	CSNK1G1	T1661	E1663K	1663	Missense	proximal	2	no	2.545	2.563	EPSD	COSMIC	1.928	Up-regulation
CK1_CK1_CK1-G_CSNK1G1_ST	P25054	APC	Q9HCP0	CSNK1G1	T1661	S1656Y	1656	Missense	distal	-5	no	2.545	2.645	EPSD	COSMIC;GDSC;CCLE	1.928	Up-regulation
CK1_CK1_CK1-G_CSNK1G1_ST	P25054	APC	Q9HCP0	CSNK1G1	T1661	S1664F	1664	Missense	distal	3	no	2.545	2.329	EPSD	COSMIC	1.928	Down-regulation
CK1_CK1_CK1-G_CSNK1G1_ST	P25054	APC	Q9HCP0	CSNK1G1	T1661	L1657R	1657	Missense	distal	-4	no	2.545	2.523	EPSD	COSMIC	1.928	Down-regulation
CK1_CK1_CK1-G_CSNK1G1_ST	P25054	APC	Q9HCP0	CSNK1G1	T1661	S1658R	1658	Missense	distal	-3	no	2.545	2.113	EPSD	COSMIC	1.928	Down-regulation
CK1_CK1_CK1-G_CSNK1G1_ST	P25054	APC	Q9HCP0	CSNK1G1	T1661	S1664Y	1664	Missense	distal	3	no	2.545	2.429	EPSD	COSMIC	1.928	Down-regulation
CK1_CK1_CK1-G_CSNK1G1_ST	P25054	APC	Q9HCP0	CSNK1G1	T1661	P1665T	1665	Missense	distal	4	no	2.545	2.233	EPSD	COSMIC	1.928	Down-regulation
CK1_CK1_CK1-G_CSNK1G1_ST	P25054	APC	Q9HCP0	CSNK1G1	S1737	A1731D	1731	Missense	distal	-6	no	1.606	2.273	EPSD	COSMIC	1.928	Gain
CK1_CK1_CK1-G_CSNK1G1_ST	P25054	APC	Q9HCP0	CSNK1G1	S1861	S1864Y	1864	Missense	distal	3	no	1.959	1.844	EPSD	COSMIC;GDSC;CCLE	1.928	Loss
CK1_CK1_CK1-G_CSNK1G1_ST	P25054	APC	Q9HCP0	CSNK1G1	S1861	R1858Q	1858	Missense	distal	-3	no	1.959	1.903	EPSD	COSMIC	1.928	Loss
CK1_CK1_CK1-G_CSNK1G1_ST	P25054	APC	Q9HCP0	CSNK1G1	S1861	F1867V	1867	Missense	distal	6	no	1.959	2.084	EPSD	COSMIC	1.928	Up-regulation
CK1_CK1_CK1-G_CSNK1G1_ST	P25054	APC	Q9HCP0	CSNK1G1	S1861	S1864F	1864	Missense	distal	3	no	1.959	1.744	EPSD	COSMIC	1.928	Loss
CK1_CK1_CK1-G_CSNK1G1_ST	P25054	APC	Q9HCP0	CSNK1G1	S1861	S1861F	1861	Missense	central	0	yes	1.959	0.000	EPSD	COSMIC	1.928	Loss
CK1_CK1_CK1-G_CSNK1G1_ST	P25054	APC	Q9HCP0	CSNK1G1	S1861	S1857L	1857	Missense	distal	-4	no	1.959	1.953	EPSD	COSMIC;GDSC;CCLE	1.928	Down-regulation
CK1_CK1_CK1-G_CSNK1G1_ST	P25054	APC	Q9HCP0	CSNK1G1	S1861	D1868H	1868	Missense	distal	7	no	1.959	1.968	EPSD	COSMIC	1.928	Up-regulation
CK1_CK1_CK1-G_CSNK1G1_ST	P25054	APC	Q9HCP0	CSNK1G1	S1861	L1862F	1862	Missense	proximal	1	no	1.959	1.745	EPSD	COSMIC	1.928	Loss
CK1_CK1_CK1-G_CSNK1G1_ST	P25054	APC	Q9HCP0	CSNK1G1	S1861	L1865P	1865	Missense	distal	4	no	1.959	1.762	EPSD	COSMIC	1.928	Loss
CK1_CK1_CK1-G_CSNK1G1_ST	P25054	APC	Q9HCP0	CSNK1G1	S1861	C1855R	1855	Missense	distal	-6	no	1.959	1.820	EPSD	COSMIC	1.928	Loss
CK1_CK1_CK1-G_CSNK1G1_ST	P25054	APC	Q9HCP0	CSNK1G1	S1863	S1864Y	1864	Missense	proximal	1	no	2.538	2.478	EPSD	COSMIC;GDSC;CCLE	1.928	Down-regulation
CK1_CK1_CK1-G_CSNK1G1_ST	P25054	APC	Q9HCP0	CSNK1G1	S1863	R1858Q	1858	Missense	distal	-5	no	2.538	2.545	EPSD	COSMIC	1.928	Up-regulation
CK1_CK1_CK1-G_CSNK1G1_ST	P25054	APC	Q9HCP0	CSNK1G1	S1863	F1867V	1867	Missense	distal	4	no	2.538	2.815	EPSD	COSMIC	1.928	Up-regulation
CK1_CK1_CK1-G_CSNK1G1_ST	P25054	APC	Q9HCP0	CSNK1G1	S1863	S1864F	1864	Missense	proximal	1	no	2.538	2.438	EPSD	COSMIC	1.928	Down-regulation
CK1_CK1_CK1-G_CSNK1G1_ST	P25054	APC	Q9HCP0	CSNK1G1	S1863	D1869G	1869	Missense	distal	6	no	2.538	2.551	EPSD	COSMIC	1.928	Up-regulation
CK1_CK1_CK1-G_CSNK1G1_ST	P25054	APC	Q9HCP0	CSNK1G1	S1863	S1861F	1861	Missense	proximal	-2	no	2.538	2.502	EPSD	COSMIC	1.928	Down-regulation
CK1_CK1_CK1-G_CSNK1G1_ST	P25054	APC	Q9HCP0	CSNK1G1	S1863	S1857L	1857	Missense	distal	-6	no	2.538	1.742	EPSD	COSMIC;GDSC;CCLE	1.928	Loss
CK1_CK1_CK1-G_CSNK1G1_ST	P25054	APC	Q9HCP0	CSNK1G1	S1863	D1868H	1868	Missense	distal	5	no	2.538	2.536	EPSD	COSMIC	1.928	Down-regulation
CK1_CK1_CK1-G_CSNK1G1_ST	P25054	APC	Q9HCP0	CSNK1G1	S1863	L1862F	1862	Missense	proximal	-1	no	2.538	2.470	EPSD	COSMIC	1.928	Down-regulation
CK1_CK1_CK1-G_CSNK1G1_ST	P25054	APC	Q9HCP0	CSNK1G1	S1863	L1865P	1865	Missense	proximal	2	no	2.538	2.685	EPSD	COSMIC	1.928	Up-regulation
CK1_CK1_CK1-G_CSNK1G1_ST	P25054	APC	Q9HCP0	CSNK1G1	S2034	L2027P	2027	Missense	distal	-7	no	2.197	2.181	EPSD	COSMIC	1.928	Down-regulation
CK1_CK1_CK1-G_CSNK1G1_ST	P25054	APC	Q9HCP0	CSNK1G1	S2034	L2030I	2030	Missense	distal	-4	no	2.197	2.180	EPSD	COSMIC	1.928	Down-regulation
CK1_CK1_CK1-G_CSNK1G1_ST	P25054	APC	Q9HCP0	CSNK1G1	S2034	D2037H	2037	Missense	distal	3	no	2.197	2.082	EPSD	COSMIC	1.928	Down-regulation
CK1_CK1_CK1-G_CSNK1G1_ST	P25054	APC	Q9HCP0	CSNK1G1	S2134	S2129L	2129	Missense	distal	-5	no	1.986	2.093	EPSD	COSMIC;GDSC	1.928	Up-regulation
CK1_CK1_CK1-G_CSNK1G1_ST	P25054	APC	Q9HCP0	CSNK1G1	S2134	D2131Y	2131	Missense	distal	-3	no	1.986	1.638	EPSD	COSMIC	1.928	Loss
CK1_CK1_CK1-G_CSNK1G1_ST	P25054	APC	Q9HCP0	CSNK1G1	S2134	S2134C	2134	Missense	central	0	yes	1.986	0.000	EPSD	COSMIC;GDSC;CCLE	1.928	Loss
CK1_CK1_CK1-G_CSNK1G1_ST	P25054	APC	Q9HCP0	CSNK1G1	S2134	S2137F	2137	Missense	distal	3	no	1.986	1.771	EPSD	COSMIC	1.928	Loss
CK1_CK1_CK1-G_CSNK1G1_ST	P25054	APC	Q9HCP0	CSNK1G1	S2134	L2136F	2136	Missense	proximal	2	no	1.986	2.092	EPSD	COSMIC	1.928	Up-regulation
CK1_CK1_CK1-G_CSNK1G1_ST	P25054	APC	Q9HCP0	CSNK1G1	S2134	A2128V	2128	Missense	distal	-6	no	1.986	2.000	EPSD	COSMIC	1.928	Up-regulation
CK1_CK1_CK1-G_CSNK1G1_ST	P25054	APC	Q9HCP0	CSNK1G1	S2134	G2141R	2141	Missense	distal	7	no	1.986	1.987	EPSD	COSMIC	1.928	Up-regulation
CK1_CK1_CK1-G_CSNK1G1_ST	P25054	APC	Q9HCP0	CSNK1G1	S2146	H2149N	2149	Missense	distal	3	no	2.097	2.168	EPSD	COSMIC	1.928	Up-regulation
CK1_CK1_CK1-G_CSNK1G1_ST	P25054	APC	Q9HCP0	CSNK1G1	S2146	P2147A	2147	Missense	proximal	1	no	2.097	2.331	EPSD	COSMIC	1.928	Up-regulation
CK1_CK1_CK1-G_CSNK1G1_ST	P25054	APC	Q9HCP0	CSNK1G1	S2146	G2145E	2145	Missense	proximal	-1	no	2.097	2.012	EPSD	COSMIC	1.928	Down-regulation
CK1_CK1_CK1-G_CSNK1G1_ST	P25054	APC	Q9HCP0	CSNK1G1	S2146	G2141R	2141	Missense	distal	-5	no	2.097	2.170	EPSD	COSMIC	1.928	Up-regulation
CK1_CK1_CK1-G_CSNK1G1_ST	P25054	APC	Q9HCP0	CSNK1G1	T2269	T2266I	2266	Missense	distal	-3	no	1.982	1.622	EPSD	COSMIC	1.928	Loss
CK1_CK1_CK1-G_CSNK1G1_ST	P25054	APC	Q9HCP0	CSNK1G1	T2269	T2266S	2266	Missense	distal	-3	no	1.982	2.106	EPSD	COSMIC	1.928	Up-regulation
CK1_CK1_CK1-G_CSNK1G1_ST	P25054	APC	Q9HCP0	CSNK1G1	T2269	T2268S	2268	Missense	proximal	-1	no	1.982	2.077	EPSD	COSMIC	1.928	Up-regulation
CK1_CK1_CK1-G_CSNK1G1_ST	P25054	APC	Q9HCP0	CSNK1G1	T2269	A2274V	2274	Missense	distal	5	no	1.982	1.986	EPSD	COSMIC;GDSC	1.928	Up-regulation
CK1_CK1_CK1-G_CSNK1G1_ST	P25054	APC	Q9HCP0	CSNK1G1	T2269	S2270C	2270	Missense	proximal	1	no	1.982	1.869	EPSD	COSMIC	1.928	Loss
CK1_CK1_CK1-G_CSNK1G1_ST	P25054	APC	Q9HCP0	CSNK1G1	T2289	A2286S	2286	Missense	distal	-3	no	1.539	2.005	EPSD	COSMIC	1.928	Gain
CK1_CK1_CK1-G_CSNK1G1_ST	P25054	APC	Q9HCP0	CSNK1G1	T2308	P2309L	2309	Missense	proximal	1	no	1.705	2.048	EPSD	COSMIC	1.928	Gain
CK1_CK1_CK1-G_CSNK1G1_ST	P25054	APC	Q9HCP0	CSNK1G1	S2349	S2355L	2355	Missense	distal	6	no	1.975	2.155	EPSD	COSMIC	1.928	Up-regulation
CK1_CK1_CK1-G_CSNK1G1_ST	P25054	APC	Q9HCP0	CSNK1G1	S2349	Q2344E	2344	Missense	distal	-5	no	1.975	1.963	EPSD	COSMIC	1.928	Down-regulation
CK1_CK1_CK1-G_CSNK1G1_ST	P25054	APC	Q9HCP0	CSNK1G1	S2349	T2356I	2356	Missense	distal	7	no	1.975	1.974	EPSD	COSMIC	1.928	Down-regulation
CK1_CK1_CK1-G_CSNK1G1_ST	P25054	APC	Q9HCP0	CSNK1G1	S2359	S2355L	2355	Missense	distal	-4	no	2.784	2.777	EPSD	COSMIC	1.928	Down-regulation
CK1_CK1_CK1-G_CSNK1G1_ST	P25054	APC	Q9HCP0	CSNK1G1	S2359	T2356I	2356	Missense	distal	-3	no	2.784	2.424	EPSD	COSMIC	1.928	Down-regulation
CK1_CK1_CK1-G_CSNK1G1_ST	P25054	APC	Q9HCP0	CSNK1G1	S2374	Q2375L	2375	Missense	proximal	1	no	2.089	2.278	EPSD	COSMIC	1.928	Up-regulation
CK1_CK1_CK1-G_CSNK1G1_ST	P25054	APC	Q9HCP0	CSNK1G1	S2374	T2379I	2379	Missense	distal	5	no	2.089	2.090	EPSD	COSMIC	1.928	Up-regulation
CK1_CK1_CK1-G_CSNK1G1_ST	P25054	APC	Q9HCP0	CSNK1G1	S2374	Q2375R	2375	Missense	proximal	1	no	2.089	2.052	EPSD	COSMIC	1.928	Down-regulation
CK1_CK1_CK1-G_CSNK1G1_ST	P25054	APC	Q9HCP0	CSNK1G1	S2374	L2378F	2378	Missense	distal	4	no	2.089	1.730	EPSD	COSMIC	1.928	Loss
CK1_CK1_CK1-G_CSNK1G1_ST	P25054	APC	Q9HCP0	CSNK1G1	S2374	Q2372P	2372	Missense	proximal	-2	no	2.089	2.060	EPSD	COSMIC	1.928	Down-regulation
CK1_CK1_CK1-G_CSNK1G1_ST	P25054	APC	Q9HCP0	CSNK1G1	S2396	N2402K	2402	Missense	distal	6	no	2.015	1.912	EPSD	COSMIC	1.928	Loss
CK1_CK1_CK1-G_CSNK1G1_ST	P25054	APC	Q9HCP0	CSNK1G1	S2396	P2392S	2392	Missense	distal	-4	no	2.015	2.075	EPSD	COSMIC	1.928	Up-regulation
CK1_CK1_CK1-G_CSNK1G1_ST	P25054	APC	Q9HCP0	CSNK1G1	S2427	S2421T	2421	Missense	distal	-6	no	2.689	2.132	EPSD	COSMIC	1.928	Down-regulation
CK1_CK1_CK1-G_CSNK1G1_ST	P25054	APC	Q9HCP0	CSNK1G1	S2427	D2430N	2430	Missense	distal	3	no	2.689	2.644	EPSD	COSMIC	1.928	Down-regulation
CK1_CK1_CK1-G_CSNK1G1_ST	P25054	APC	Q9HCP0	CSNK1G1	S2427	E2428K	2428	Missense	proximal	1	no	2.689	2.669	EPSD	COSMIC	1.928	Down-regulation
CK1_CK1_CK1-G_CSNK1G1_ST	P25054	APC	Q9HCP0	CSNK1G1	S2427	T2422S	2422	Missense	distal	-5	no	2.689	2.626	EPSD	COSMIC	1.928	Down-regulation
CK1_CK1_CK1-G_CSNK1G1_ST	P25054	APC	Q9HCP0	CSNK1G1	S2466	P2467S	2467	Missense	proximal	1	no	1.876	2.105	EPSD	COSMIC;GDSC;CCLE	1.928	Gain
CK1_CK1_CK1-G_CSNK1G1_ST	P25054	APC	Q9HCP0	CSNK1G1	S2466	P2467T	2467	Missense	proximal	1	no	1.876	1.963	EPSD	COSMIC	1.928	Gain
CK1_CK1_CK1-G_CSNK1G1_ST	P25054	APC	Q9HCP0	CSNK1G1	S2466	E2463D	2463	Missense	distal	-3	no	1.876	2.260	EPSD	COSMIC	1.928	Gain
CK1_CK1_CK1-G_CSNK1G1_ST	P25054	APC	Q9HCP0	CSNK1G1	S2575	S2577L	2577	Missense	proximal	2	no	2.091	2.146	EPSD	COSMIC	1.928	Up-regulation
CK1_CK1_CK1-G_CSNK1G1_ST	P25054	APC	Q9HCP0	CSNK1G1	S2575	S2581N	2581	Missense	distal	6	no	2.091	2.087	EPSD	COSMIC	1.928	Down-regulation
CK1_CK1_CK1-G_CSNK1G1_ST	P25054	APC	Q9HCP0	CSNK1G1	S2575	S2570L	2570	Missense	distal	-5	no	2.091	2.197	EPSD	COSMIC	1.928	Up-regulation
CK1_CK1_CK1-G_CSNK1G1_ST	P25054	APC	Q9HCP0	CSNK1G1	S2575	I2573V	2573	Missense	proximal	-2	no	2.091	2.113	EPSD	COSMIC	1.928	Up-regulation
CK1_CK1_CK1-G_CSNK1G1_ST	P25054	APC	Q9HCP0	CSNK1G1	S2575	S2569R	2569	Missense	distal	-6	no	2.091	1.169	EPSD	COSMIC;GDSC;CCLE	1.928	Loss
CK1_CK1_CK1-G_CSNK1G1_ST	P25054	APC	Q9HCP0	CSNK1G1	S2627	Q2628H	2628	Missense	proximal	1	no	2.082	2.034	EPSD	COSMIC	1.928	Down-regulation
CK1_CK1_CK1-G_CSNK1G1_ST	P25054	APC	Q9HCP0	CSNK1G1	S2627	G2633S	2633	Missense	distal	6	no	2.082	2.136	EPSD	COSMIC	1.928	Up-regulation
CK1_CK1_CK1-G_CSNK1G1_ST	P25054	APC	Q9HCP0	CSNK1G1	S2627	S2631F	2631	Missense	distal	4	no	2.082	1.868	EPSD	COSMIC	1.928	Loss
CK1_CK1_CK1-G_CSNK1G1_ST	P25054	APC	Q9HCP0	CSNK1G1	S2627	S2627F	2627	Missense	central	0	yes	2.082	0.000	EPSD	COSMIC	1.928	Loss
CK1_CK1_CK1-G_CSNK1G1_ST	P25054	APC	Q9HCP0	CSNK1G1	S2627	P2622S	2622	Missense	distal	-5	no	2.082	1.937	EPSD	COSMIC	1.928	Down-regulation
CK1_CK1_CK1-G_CSNK1G1_ST	P25054	APC	Q9HCP0	CSNK1G1	S2627	S2621F	2621	Missense	distal	-6	no	2.082	1.165	EPSD	COSMIC	1.928	Loss
CK1_CK1_CK1-G_CSNK1G1_ST	P25054	APC	Q9HCP0	CSNK1G1	S2627	P2622L	2622	Missense	distal	-5	no	2.082	2.044	EPSD	COSMIC	1.928	Down-regulation
CK1_CK1_CK1-G_CSNK1G1_ST	P25054	APC	Q9HCP0	CSNK1G1	S2627	S2625N	2625	Missense	proximal	-2	no	2.082	2.047	EPSD	COSMIC	1.928	Down-regulation
CK1_CK1_CK1-G_CSNK1G1_ST	O75581	LRP6	Q9HCP0	CSNK1G1	S646	N651S	651	Missense	distal	5	no	2.084	2.089	EPSD	COSMIC	1.928	Up-regulation
CK1_CK1_CK1-G_CSNK1G1_ST	O75581	LRP6	Q9HCP0	CSNK1G1	T1408	G1406W	1406	Missense	proximal	-2	no	1.931	1.893	EPSD	COSMIC	1.928	Loss
CK1_CK1_CK1-G_CSNK1G1_ST	O75581	LRP6	Q9HCP0	CSNK1G1	T1408	N1411T	1411	Missense	distal	3	no	1.931	1.878	EPSD	COSMIC	1.928	Loss
CK1_CK1_CK1-G_CSNK1G1_ST	O75581	LRP6	Q9HCP0	CSNK1G1	T1511	S1508R	1508	Missense	distal	-3	no	3.064	2.632	EPSD	COSMIC	1.928	Down-regulation
CK1_CK1_CK1-G_CSNK1G1_ST	O75581	LRP6	Q9HCP0	CSNK1G1	T1511	S1514A	1514	Missense	distal	3	no	3.064	2.926	EPSD	COSMIC	1.928	Down-regulation
CK1_CK1_CK1-G_CSNK1G1_ST	O75581	LRP6	Q9HCP0	CSNK1G1	T1511	N1507K	1507	Missense	distal	-4	no	3.064	3.041	EPSD	COSMIC	1.928	Down-regulation
CK1_CK1_CK1-G_CSNK1G1_ST	Q04206	RELA	Q9HCP0	CSNK1G1	S311	M313I	313	Missense	proximal	2	no	1.998	1.975	EPSD	COSMIC	1.928	Down-regulation
CK1_CK1_CK1-G_CSNK1G1_ST	Q04206	RELA	Q9HCP0	CSNK1G1	S311	K314N	314	Missense	distal	3	no	1.998	2.087	EPSD	COSMIC	1.928	Up-regulation
CK1_CK1_CK1-G_CSNK1G1_ST	Q04206	RELA	Q9HCP0	CSNK1G1	S311	T305A	305	Missense	distal	-6	no	1.998	1.679	EPSD	COSMIC	1.928	Loss
CK1_CK1_CK1-G_CSNK1G1_ST	Q04206	RELA	Q9HCP0	CSNK1G1	S536	F534L	534	Missense	proximal	-2	no	3.108	3.131	PhosphoSitePlus	COSMIC	1.928	Up-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	P12931	SRC	O14757	CHEK1	S12	K9T	9	Missense	distal	-3	no	8.908	-7.835	EPSD	COSMIC	5.604	Loss
CAMK_CAMKL_CHK1_CHEK1_ST	P12931	SRC	O14757	CHEK1	S12	R16H	16	Missense	distal	4	no	8.908	9.069	EPSD	COSMIC	5.604	Up-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	P12931	SRC	O14757	CHEK1	S12	R15C	15	Missense	distal	3	no	8.908	7.961	EPSD	COSMIC	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	P12931	SRC	O14757	CHEK1	S17	R16H	16	Missense	proximal	-1	no	9.633	9.758	EPSD	COSMIC	5.604	Up-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	P12931	SRC	O14757	CHEK1	S17	A21T	21	Missense	distal	4	no	9.633	9.451	EPSD	COSMIC	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	P12931	SRC	O14757	CHEK1	S17	R15C	15	Missense	proximal	-2	no	9.633	9.581	EPSD	COSMIC	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	P12931	SRC	O14757	CHEK1	S17	P20S	20	Missense	distal	3	no	9.633	9.303	EPSD	COSMIC	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	P12931	SRC	O14757	CHEK1	S43	A44V	44	Missense	proximal	1	no	5.985	5.960	EPSD	COSMIC	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	P12931	SRC	O14757	CHEK1	S43	D45N	45	Missense	proximal	2	no	5.985	5.700	EPSD	COSMIC	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	P12931	SRC	O14757	CHEK1	S43	G46S	46	Missense	distal	3	no	5.985	6.072	EPSD	COSMIC	5.604	Up-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	P12931	SRC	O14757	CHEK1	S51	A44V	44	Missense	distal	-7	no	11.266	10.609	PhosphoSitePlus;EPSD	COSMIC	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	P12931	SRC	O14757	CHEK1	S51	D45N	45	Missense	distal	-6	no	11.266	11.479	PhosphoSitePlus;EPSD	COSMIC	5.604	Up-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	P12931	SRC	O14757	CHEK1	S51	A57V	57	Missense	distal	6	no	11.266	11.153	PhosphoSitePlus;EPSD	COSMIC	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	P12931	SRC	O14757	CHEK1	S51	G46S	46	Missense	distal	-5	no	11.266	11.220	PhosphoSitePlus;EPSD	COSMIC	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	P12931	SRC	O14757	CHEK1	T101	E100Q	100	Missense	proximal	-1	no	6.978	7.084	EPSD	COSMIC	5.604	Up-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	P12931	SRC	O14757	CHEK1	T246	V247L	247	Missense	proximal	1	no	7.750	7.748	EPSD	COSMIC	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	P12931	SRC	O14757	CHEK1	T246	K252N	252	Missense	distal	6	no	7.750	7.885	EPSD	COSMIC	5.604	Up-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	P12931	SRC	O14757	CHEK1	T246	T250M	250	Missense	distal	4	no	7.750	7.849	EPSD	COSMIC;GDSC;CCLE	5.604	Up-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	P12931	SRC	O14757	CHEK1	T443	V448L	448	Missense	distal	5	no	6.263	6.104	EPSD	COSMIC	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	P12931	SRC	O14757	CHEK1	T443	Y439S	439	Missense	distal	-4	no	6.263	6.440	EPSD	COSMIC	5.604	Up-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	P12931	SRC	O14757	CHEK1	T443	L438R	438	Missense	distal	-5	no	6.263	3.286	EPSD	COSMIC	5.604	Loss
CAMK_CAMKL_CHK1_CHEK1_ST	Q6PD62	CTR9	O14757	CHEK1	T39	Q36R	36	Missense	distal	-3	no	3.310	10.517	EPSD	COSMIC	5.604	Gain
CAMK_CAMKL_CHK1_CHEK1_ST	Q6PD62	CTR9	O14757	CHEK1	T263	S267N	267	Missense	distal	4	no	12.864	12.884	EPSD	COSMIC;GDSC;CCLE	5.604	Up-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q6PD62	CTR9	O14757	CHEK1	T766	L764F	764	Missense	proximal	-2	no	8.467	8.652	EPSD	COSMIC	5.604	Up-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q6PD62	CTR9	O14757	CHEK1	S1054	S1059F	1059	Missense	distal	5	no	9.751	9.426	EPSD	COSMIC	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q6PD62	CTR9	O14757	CHEK1	S1081	R1075K	1075	Missense	distal	-6	no	8.022	8.012	PhosphoSitePlus	COSMIC	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q6PD62	CTR9	O14757	CHEK1	S1081	R1080W	1080	Missense	proximal	-1	no	8.022	8.139	PhosphoSitePlus	COSMIC	5.604	Up-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q6PD62	CTR9	O14757	CHEK1	S1081	R1077Q	1077	Missense	distal	-4	no	8.022	8.182	PhosphoSitePlus	COSMIC;GDSC	5.604	Up-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	P11047	LAMC1	O14757	CHEK1	S159	R156C	156	Missense	distal	-3	no	7.612	-0.479	EPSD	COSMIC;GDSC;CCLE	5.604	Loss
CAMK_CAMKL_CHK1_CHEK1_ST	P11047	LAMC1	O14757	CHEK1	T258	R255C	255	Missense	distal	-3	no	13.605	5.514	PhosphoSitePlus	COSMIC	5.604	Loss
CAMK_CAMKL_CHK1_CHEK1_ST	P11047	LAMC1	O14757	CHEK1	S1552	D1547Y	1547	Missense	distal	-5	no	6.723	6.814	EPSD	COSMIC	5.604	Up-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	P11047	LAMC1	O14757	CHEK1	S1559	K1566N	1566	Missense	distal	7	no	14.923	14.984	EPSD	COSMIC	5.604	Up-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	P11047	LAMC1	O14757	CHEK1	S1559	A1565S	1565	Missense	distal	6	no	14.923	14.535	EPSD	COSMIC	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q9NUU7	DDX19A	O14757	CHEK1	T34	G36C	36	Missense	proximal	2	no	7.302	7.006	EPSD	COSMIC	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q9NUU7	DDX19A	O14757	CHEK1	S92	P86T	86	Missense	distal	-6	no	7.232	7.204	PhosphoSitePlus	COSMIC	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q9NUU7	DDX19A	O14757	CHEK1	S92	S85F	85	Missense	distal	-7	no	7.232	5.500	PhosphoSitePlus	COSMIC	5.604	Loss
CAMK_CAMKL_CHK1_CHEK1_ST	Q9NUU7	DDX19A	O14757	CHEK1	S346	A350S	350	Missense	distal	4	no	7.002	6.809	EPSD	COSMIC	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q9NUU7	DDX19A	O14757	CHEK1	S353	A350S	350	Missense	distal	-3	no	8.920	5.936	EPSD	COSMIC	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q9NUU7	DDX19A	O14757	CHEK1	T467	D469N	469	Missense	proximal	2	no	11.433	11.148	EPSD	COSMIC	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	P22626	HNRNPA2B1	O14757	CHEK1	S85	M79R	79	Missense	distal	-6	no	7.328	7.186	EPSD	COSMIC	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	P22626	HNRNPA2B1	O14757	CHEK1	S85	A81G	81	Missense	distal	-4	no	7.328	7.283	EPSD	COSMIC	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	P22626	HNRNPA2B1	O14757	CHEK1	S102	S102A	102	Missense	central	0	yes	9.122	0.000	EPSD	COSMIC	5.604	Loss
CAMK_CAMKL_CHK1_CHEK1_ST	P22626	HNRNPA2B1	O14757	CHEK1	S102	A107V	107	Missense	distal	5	no	9.122	9.018	EPSD	COSMIC	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	P22626	HNRNPA2B1	O14757	CHEK1	S102	G106E	106	Missense	distal	4	no	9.122	9.013	EPSD	COSMIC	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	P22626	HNRNPA2B1	O14757	CHEK1	T176	H180R	180	Missense	distal	4	no	8.724	8.563	EPSD	COSMIC	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	P22626	HNRNPA2B1	O14757	CHEK1	T176	V170A	170	Missense	distal	-6	no	8.724	8.586	EPSD	COSMIC;GDSC;CCLE	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	P22626	HNRNPA2B1	O14757	CHEK1	T176	T176A	176	Missense	central	0	yes	8.724	0.000	EPSD	COSMIC	5.604	Loss
CAMK_CAMKL_CHK1_CHEK1_ST	P22626	HNRNPA2B1	O14757	CHEK1	S189	R190G	190	Missense	proximal	1	no	8.250	8.242	EPSD	COSMIC	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	P22626	HNRNPA2B1	O14757	CHEK1	S189	A187T	187	Missense	proximal	-2	no	8.250	8.390	EPSD	COSMIC	5.604	Up-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	P22626	HNRNPA2B1	O14757	CHEK1	S231	N226K	226	Missense	distal	-5	no	7.700	8.594	EPSD	COSMIC	5.604	Up-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	P84098	RPL19	O14757	CHEK1	S12	S12A	12	Missense	central	0	yes	11.238	0.000	EPSD;PhosphoSitePlus	COSMIC	5.604	Loss
CAMK_CAMKL_CHK1_CHEK1_ST	P84098	RPL19	O14757	CHEK1	S12	K8E	8	Missense	distal	-4	no	11.238	11.340	EPSD;PhosphoSitePlus	COSMIC	5.604	Up-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	P84098	RPL19	O14757	CHEK1	T29	I32L	32	Missense	distal	3	no	6.088	6.028	EPSD	COSMIC	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	P84098	RPL19	O14757	CHEK1	T29	N27K	27	Missense	proximal	-2	no	6.088	5.817	EPSD	COSMIC	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	P84098	RPL19	O14757	CHEK1	T56	R52P	52	Missense	distal	-4	no	5.624	5.552	PhosphoSitePlus;EPSD	COSMIC	5.604	Loss
CAMK_CAMKL_CHK1_CHEK1_ST	P84098	RPL19	O14757	CHEK1	T56	R62Q	62	Missense	distal	6	no	5.624	5.617	PhosphoSitePlus;EPSD	COSMIC	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	P84098	RPL19	O14757	CHEK1	T56	R60Q	60	Missense	distal	4	no	5.624	5.623	PhosphoSitePlus;EPSD	COSMIC	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	P84098	RPL19	O14757	CHEK1	T67	R71W	71	Missense	distal	4	no	10.349	10.412	EPSD	COSMIC	5.604	Up-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	P84098	RPL19	O14757	CHEK1	T67	R70H	70	Missense	distal	3	no	10.349	10.379	EPSD	COSMIC	5.604	Up-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	P84098	RPL19	O14757	CHEK1	T67	R62Q	62	Missense	distal	-5	no	10.349	9.952	EPSD	COSMIC	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	P84098	RPL19	O14757	CHEK1	T67	R60Q	60	Missense	distal	-7	no	10.349	10.607	EPSD	COSMIC	5.604	Up-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	P84098	RPL19	O14757	CHEK1	T84	M89I	89	Missense	distal	5	no	9.913	9.882	EPSD	COSMIC	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	P84098	RPL19	O14757	CHEK1	T84	G77C	77	Missense	distal	-7	no	9.913	9.147	EPSD	COSMIC	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	P84098	RPL19	O14757	CHEK1	S189	I185F	185	Missense	distal	-4	no	6.586	6.324	EPSD	COSMIC	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	P84098	RPL19	O14757	CHEK1	S189	T194A	194	Missense	distal	5	no	6.586	6.827	EPSD	COSMIC	5.604	Up-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	P67809	YBX1	O14757	CHEK1	S176	P178S	178	Missense	proximal	2	no	6.877	6.953	EPSD	COSMIC	5.604	Up-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	P67809	YBX1	O14757	CHEK1	S176	E172K	172	Missense	distal	-4	no	6.877	6.774	EPSD	COSMIC	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	P67809	YBX1	O14757	CHEK1	S176	S174L	174	Missense	proximal	-2	no	6.877	6.982	EPSD	COSMIC	5.604	Up-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	P67809	YBX1	O14757	CHEK1	S176	E179K	179	Missense	distal	3	no	6.877	6.061	EPSD	COSMIC	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q7Z2Z1	TICRR	O14757	CHEK1	T207	Y209F	209	Missense	proximal	2	no	8.967	9.119	EPSD	COSMIC	5.604	Up-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q7Z2Z1	TICRR	O14757	CHEK1	T626	R623I	623	Missense	distal	-3	no	8.697	-0.061	EPSD	COSMIC	5.604	Loss
CAMK_CAMKL_CHK1_CHEK1_ST	Q7Z2Z1	TICRR	O14757	CHEK1	S836	E840A	840	Missense	distal	4	no	7.648	7.883	EPSD	COSMIC	5.604	Up-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q7Z2Z1	TICRR	O14757	CHEK1	S836	R832C	832	Missense	distal	-4	no	7.648	7.274	EPSD	COSMIC	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q7Z2Z1	TICRR	O14757	CHEK1	S836	S829G	829	Missense	distal	-7	no	7.648	7.427	EPSD	COSMIC	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q7Z2Z1	TICRR	O14757	CHEK1	S836	S829R	829	Missense	distal	-7	no	7.648	7.389	EPSD	COSMIC	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q7Z2Z1	TICRR	O14757	CHEK1	S865	H863P	863	Missense	proximal	-2	no	12.767	12.887	EPSD;PhosphoSitePlus	COSMIC;GDSC;CCLE	5.604	Up-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q7Z2Z1	TICRR	O14757	CHEK1	S938	V942A	942	Missense	distal	4	no	11.595	11.678	EPSD	COSMIC	5.604	Up-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q7Z2Z1	TICRR	O14757	CHEK1	S1045	H1044Y	1044	Missense	proximal	-1	no	9.058	9.100	EPSD;PhosphoSitePlus	COSMIC	5.604	Up-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q7Z2Z1	TICRR	O14757	CHEK1	S1057	R1063Q	1063	Missense	distal	6	no	9.076	9.069	EPSD	COSMIC;GDSC	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q7Z2Z1	TICRR	O14757	CHEK1	S1057	N1056K	1056	Missense	proximal	-1	no	9.076	8.870	EPSD	COSMIC	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q7Z2Z1	TICRR	O14757	CHEK1	S1125	Q1129H	1129	Missense	distal	4	no	9.804	9.966	EPSD	COSMIC	5.604	Up-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q7Z2Z1	TICRR	O14757	CHEK1	S1125	T1127I	1127	Missense	proximal	2	no	9.804	9.690	EPSD	COSMIC;GDSC	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q7Z2Z1	TICRR	O14757	CHEK1	S1125	R1122T	1122	Missense	distal	-3	no	9.804	-10.765	EPSD	COSMIC	5.604	Loss
CAMK_CAMKL_CHK1_CHEK1_ST	Q7Z2Z1	TICRR	O14757	CHEK1	S1161	E1155D	1155	Missense	distal	-6	no	6.137	6.087	EPSD	COSMIC;GDSC	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q7Z2Z1	TICRR	O14757	CHEK1	S1161	G1164S	1164	Missense	distal	3	no	6.137	6.224	EPSD	COSMIC	5.604	Up-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q7Z2Z1	TICRR	O14757	CHEK1	S1224	P1223S	1223	Missense	proximal	-1	no	6.096	5.649	EPSD	COSMIC	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q7Z2Z1	TICRR	O14757	CHEK1	S1224	P1229L	1229	Missense	distal	5	no	6.096	5.934	EPSD	COSMIC	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q7Z2Z1	TICRR	O14757	CHEK1	S1224	S1231L	1231	Missense	distal	7	no	6.096	6.088	EPSD	COSMIC	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q7Z2Z1	TICRR	O14757	CHEK1	S1224	P1228L	1228	Missense	distal	4	no	6.096	5.992	EPSD	COSMIC	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q7Z2Z1	TICRR	O14757	CHEK1	S1394	E1397K	1397	Missense	distal	3	no	6.766	5.950	EPSD	COSMIC	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q7Z2Z1	TICRR	O14757	CHEK1	S1428	P1434L	1434	Missense	distal	6	no	6.687	6.477	EPSD	COSMIC	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q7Z2Z1	TICRR	O14757	CHEK1	S1714	G1711E	1711	Missense	distal	-3	no	7.331	8.017	EPSD	COSMIC	5.604	Up-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q7Z2Z1	TICRR	O14757	CHEK1	S1714	L1709V	1709	Missense	distal	-5	no	7.331	3.854	EPSD	COSMIC	5.604	Loss
CAMK_CAMKL_CHK1_CHEK1_ST	Q7Z2Z1	TICRR	O14757	CHEK1	S1806	A1811S	1811	Missense	distal	5	no	6.466	6.448	EPSD	COSMIC	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q7Z2Z1	TICRR	O14757	CHEK1	S1894	R1891H	1891	Missense	distal	-3	no	7.027	1.218	EPSD;PhosphoSitePlus	COSMIC	5.604	Loss
CAMK_CAMKL_CHK1_CHEK1_ST	Q7Z2Z1	TICRR	O14757	CHEK1	S1894	K1900E	1900	Missense	distal	6	no	7.027	6.758	EPSD;PhosphoSitePlus	COSMIC	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q7Z2Z1	TICRR	O14757	CHEK1	S1894	R1899W	1899	Missense	distal	5	no	7.027	6.859	EPSD;PhosphoSitePlus	COSMIC	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q7Z2Z1	TICRR	O14757	CHEK1	S1894	R1890H	1890	Missense	distal	-4	no	7.027	6.830	EPSD;PhosphoSitePlus	COSMIC	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q7Z2Z1	TICRR	O14757	CHEK1	S1894	R1890C	1890	Missense	distal	-4	no	7.027	6.654	EPSD;PhosphoSitePlus	COSMIC	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q7Z2Z1	TICRR	O14757	CHEK1	T1898	R1891H	1891	Missense	distal	-7	no	9.472	9.413	PhosphoSitePlus;EPSD	COSMIC	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q7Z2Z1	TICRR	O14757	CHEK1	T1898	K1900E	1900	Missense	proximal	2	no	9.472	9.430	PhosphoSitePlus;EPSD	COSMIC	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q7Z2Z1	TICRR	O14757	CHEK1	T1898	R1899W	1899	Missense	proximal	1	no	9.472	9.442	PhosphoSitePlus;EPSD	COSMIC	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q9NRL2	BAZ1A	O14757	CHEK1	S601	T603I	603	Missense	proximal	2	no	7.837	7.723	EPSD	COSMIC;GDSC	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q9NRL2	BAZ1A	O14757	CHEK1	S601	D607H	607	Missense	distal	6	no	7.837	8.397	EPSD	COSMIC	5.604	Up-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q9NRL2	BAZ1A	O14757	CHEK1	S960	A963V	963	Missense	distal	3	no	9.431	9.675	EPSD	COSMIC	5.604	Up-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q9NRL2	BAZ1A	O14757	CHEK1	S960	G958E	958	Missense	proximal	-2	no	9.431	9.359	EPSD	COSMIC	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q9NRL2	BAZ1A	O14757	CHEK1	S1205	R1200H	1200	Missense	distal	-5	no	9.737	7.272	EPSD	COSMIC	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q9NRL2	BAZ1A	O14757	CHEK1	S1205	R1207K	1207	Missense	proximal	2	no	9.737	10.423	EPSD	COSMIC	5.604	Up-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q9NRL2	BAZ1A	O14757	CHEK1	S1206	R1200H	1200	Missense	distal	-6	no	9.311	9.420	EPSD	COSMIC	5.604	Up-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q9NRL2	BAZ1A	O14757	CHEK1	S1296	Y1294H	1294	Missense	proximal	-2	no	9.263	9.315	EPSD	COSMIC	5.604	Up-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q9NRL2	BAZ1A	O14757	CHEK1	S1320	S1314T	1314	Missense	distal	-6	no	8.923	8.992	PhosphoSitePlus	COSMIC	5.604	Up-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	P54132	BLM	O14757	CHEK1	S42	T41A	41	Missense	proximal	-1	no	6.851	6.979	EPSD	COSMIC	5.604	Up-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	P54132	BLM	O14757	CHEK1	S42	F35Y	35	Missense	distal	-7	no	6.851	6.924	EPSD	COSMIC	5.604	Up-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	P54132	BLM	O14757	CHEK1	S42	F37Y	37	Missense	distal	-5	no	6.851	6.542	EPSD	COSMIC	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	P54132	BLM	O14757	CHEK1	S42	N45S	45	Missense	distal	3	no	6.851	6.009	EPSD	COSMIC	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	P54132	BLM	O14757	CHEK1	S42	S42Y	42	Missense	central	0	yes	6.851	0.000	EPSD	COSMIC	5.604	Loss
CAMK_CAMKL_CHK1_CHEK1_ST	P54132	BLM	O14757	CHEK1	S104	G102D	102	Missense	proximal	-2	no	10.128	10.042	EPSD	COSMIC	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	P54132	BLM	O14757	CHEK1	S104	F111V	111	Missense	distal	7	no	10.128	10.686	EPSD	COSMIC	5.604	Up-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	P54132	BLM	O14757	CHEK1	S104	P109L	109	Missense	distal	5	no	10.128	9.966	EPSD	COSMIC	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	P54132	BLM	O14757	CHEK1	S104	P109S	109	Missense	distal	5	no	10.128	10.210	EPSD	COSMIC	5.604	Up-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	P54132	BLM	O14757	CHEK1	S104	R101T	101	Missense	distal	-3	no	10.128	-10.441	EPSD	COSMIC	5.604	Loss
CAMK_CAMKL_CHK1_CHEK1_ST	P54132	BLM	O14757	CHEK1	S104	D110Y	110	Missense	distal	6	no	10.128	11.053	EPSD	COSMIC	5.604	Up-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	P54132	BLM	O14757	CHEK1	S104	S104L	104	Missense	central	0	yes	10.128	0.000	EPSD	COSMIC	5.604	Loss
CAMK_CAMKL_CHK1_CHEK1_ST	P54132	BLM	O14757	CHEK1	S104	L107S	107	Missense	distal	3	no	10.128	10.562	EPSD	COSMIC	5.604	Up-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	P54132	BLM	O14757	CHEK1	T182	H176D	176	Missense	distal	-6	no	10.690	10.488	EPSD;PhosphoSitePlus	COSMIC	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	P54132	BLM	O14757	CHEK1	S269	K271R	271	Missense	proximal	2	no	9.017	8.331	EPSD	COSMIC	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	P54132	BLM	O14757	CHEK1	T359	E356K	356	Missense	distal	-3	no	2.702	5.965	EPSD	COSMIC	5.604	Gain
CAMK_CAMKL_CHK1_CHEK1_ST	P54132	BLM	O14757	CHEK1	S367	H374Y	374	Missense	distal	7	no	6.144	5.829	EPSD	COSMIC	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	P54132	BLM	O14757	CHEK1	S367	I366T	366	Missense	proximal	-1	no	6.144	6.231	EPSD	COSMIC;GDSC	5.604	Up-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	P54132	BLM	O14757	CHEK1	S367	C361Y	361	Missense	distal	-6	no	6.144	6.270	EPSD	COSMIC;CCLE	5.604	Up-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	P54132	BLM	O14757	CHEK1	S367	A363S	363	Missense	distal	-4	no	6.144	5.764	EPSD	COSMIC	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	P54132	BLM	O14757	CHEK1	S367	H374D	374	Missense	distal	7	no	6.144	6.735	EPSD	COSMIC	5.604	Up-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	P54132	BLM	O14757	CHEK1	T412	N417S	417	Missense	distal	5	no	6.894	6.896	EPSD	COSMIC	5.604	Up-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	P54132	BLM	O14757	CHEK1	T412	D415Y	415	Missense	distal	3	no	6.894	4.109	EPSD	COSMIC	5.604	Loss
CAMK_CAMKL_CHK1_CHEK1_ST	P54132	BLM	O14757	CHEK1	S517	R510K	510	Missense	distal	-7	no	5.016	6.196	EPSD	COSMIC	5.604	Gain
CAMK_CAMKL_CHK1_CHEK1_ST	P54132	BLM	O14757	CHEK1	S539	Q533H	533	Missense	distal	-6	no	8.908	8.936	PhosphoSitePlus;EPSD	COSMIC	5.604	Up-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	P54132	BLM	O14757	CHEK1	S597	R599K	599	Missense	proximal	2	no	5.636	6.322	EPSD	COSMIC	5.604	Up-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	P54132	BLM	O14757	CHEK1	S597	G590A	590	Missense	distal	-7	no	5.636	6.307	EPSD	COSMIC	5.604	Up-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	P54132	BLM	O14757	CHEK1	S602	D606N	606	Missense	distal	4	no	7.824	7.793	EPSD	COSMIC	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	P54132	BLM	O14757	CHEK1	S602	R599K	599	Missense	distal	-3	no	7.824	3.999	EPSD	COSMIC	5.604	Loss
CAMK_CAMKL_CHK1_CHEK1_ST	P54132	BLM	O14757	CHEK1	S646	S646G	646	Missense	central	0	yes	9.083	0.000	EPSD;PhosphoSitePlus	COSMIC	5.604	Loss
CAMK_CAMKL_CHK1_CHEK1_ST	P54132	BLM	O14757	CHEK1	S823	M816I	816	Missense	distal	-7	no	6.061	5.819	EPSD	COSMIC	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	P54132	BLM	O14757	CHEK1	S823	P822S	822	Missense	proximal	-1	no	6.061	5.614	EPSD	COSMIC	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	P54132	BLM	O14757	CHEK1	S1128	S1121F	1121	Missense	distal	-7	no	8.259	6.527	EPSD	COSMIC	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	P54132	BLM	O14757	CHEK1	S1128	S1121Y	1121	Missense	distal	-7	no	8.259	6.601	EPSD	COSMIC;CCLE	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	P54132	BLM	O14757	CHEK1	S1128	G1134C	1134	Missense	distal	6	no	8.259	8.428	EPSD	COSMIC	5.604	Up-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	P54132	BLM	O14757	CHEK1	S1128	I1126M	1126	Missense	proximal	-2	no	8.259	8.273	EPSD	COSMIC	5.604	Up-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	P54132	BLM	O14757	CHEK1	S1375	T1371M	1371	Missense	distal	-4	no	5.848	6.044	EPSD	COSMIC	5.604	Up-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	P54132	BLM	O14757	CHEK1	S1375	S1373F	1373	Missense	proximal	-2	no	5.848	6.138	EPSD	COSMIC	5.604	Up-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	P54132	BLM	O14757	CHEK1	S1375	S1368Y	1368	Missense	distal	-7	no	5.848	4.190	EPSD	COSMIC	5.604	Loss
CAMK_CAMKL_CHK1_CHEK1_ST	P54132	BLM	O14757	CHEK1	S1375	S1380R	1380	Missense	distal	5	no	5.848	5.745	EPSD	COSMIC	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	P54132	BLM	O14757	CHEK1	S1375	A1382T	1382	Missense	distal	7	no	5.848	5.732	EPSD	COSMIC	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	P54132	BLM	O14757	CHEK1	S1383	S1380R	1380	Missense	distal	-3	no	-2.295	7.401	EPSD	COSMIC	5.604	Gain
CAMK_CAMKL_CHK1_CHEK1_ST	O00716	E2F3	O14757	CHEK1	S124	G120D	120	Missense	distal	-4	no	12.407	12.443	PhosphoSitePlus	COSMIC	5.604	Up-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	O00716	E2F3	O14757	CHEK1	T181	T177S	177	Missense	distal	-4	no	8.888	8.940	EPSD	COSMIC	5.604	Up-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	O00716	E2F3	O14757	CHEK1	T181	E175Q	175	Missense	distal	-6	no	8.888	9.012	EPSD	COSMIC	5.604	Up-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	O00716	E2F3	O14757	CHEK1	T181	K176N	176	Missense	distal	-5	no	8.888	7.995	EPSD	COSMIC	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	O00716	E2F3	O14757	CHEK1	T181	T181A	181	Missense	central	0	yes	8.888	0.000	EPSD	COSMIC	5.604	Loss
CAMK_CAMKL_CHK1_CHEK1_ST	O00716	E2F3	O14757	CHEK1	T181	L183V	183	Missense	proximal	2	no	8.888	9.176	EPSD	COSMIC	5.604	Up-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	O00716	E2F3	O14757	CHEK1	T181	T177M	177	Missense	distal	-4	no	8.888	9.084	EPSD	COSMIC	5.604	Up-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	O00716	E2F3	O14757	CHEK1	T181	L183F	183	Missense	proximal	2	no	8.888	9.138	EPSD	COSMIC	5.604	Up-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	O00716	E2F3	O14757	CHEK1	T181	Y179C	179	Missense	proximal	-2	no	8.888	8.824	EPSD	COSMIC	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	O00716	E2F3	O14757	CHEK1	S235	K234N	234	Missense	proximal	-1	no	8.306	8.512	EPSD	COSMIC	5.604	Up-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	O00716	E2F3	O14757	CHEK1	S235	K234T	234	Missense	proximal	-1	no	8.306	8.498	EPSD	COSMIC	5.604	Up-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	O00716	E2F3	O14757	CHEK1	S308	D312E	312	Missense	distal	4	no	6.273	6.181	EPSD	COSMIC	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	O00716	E2F3	O14757	CHEK1	S308	Q302E	302	Missense	distal	-6	no	6.273	6.149	EPSD	COSMIC	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	O00716	E2F3	O14757	CHEK1	S308	S308N	308	Missense	central	0	yes	6.273	0.000	EPSD	COSMIC	5.604	Loss
CAMK_CAMKL_CHK1_CHEK1_ST	O14757	CHEK1	O14757	CHEK1	S280	R275S	275	Missense	distal	-5	no	10.080	9.868	EPSD	COSMIC	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	O14757	CHEK1	O14757	CHEK1	S280	P276L	276	Missense	distal	-4	no	10.080	9.895	EPSD	COSMIC	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	O14757	CHEK1	O14757	CHEK1	S296	F300L	300	Missense	distal	4	no	6.583	6.521	PhosphoSitePlus;EPSD	COSMIC	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	O14757	CHEK1	O14757	CHEK1	S296	P302A	302	Missense	distal	6	no	6.583	6.352	PhosphoSitePlus;EPSD	COSMIC	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	O14757	CHEK1	O14757	CHEK1	S316	P321L	321	Missense	distal	5	no	5.834	5.672	EPSD;PhosphoSitePlus	COSMIC	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	O14757	CHEK1	O14757	CHEK1	S316	P321T	321	Missense	distal	5	no	5.834	5.693	EPSD;PhosphoSitePlus	COSMIC	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	O14757	CHEK1	O14757	CHEK1	S316	R322C	322	Missense	distal	6	no	5.834	6.128	EPSD;PhosphoSitePlus	COSMIC	5.604	Up-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	O14757	CHEK1	O14757	CHEK1	S316	V312M	312	Missense	distal	-4	no	5.834	5.678	EPSD;PhosphoSitePlus	COSMIC;CCLE	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	O14757	CHEK1	O14757	CHEK1	S316	E320K	320	Missense	distal	4	no	5.834	5.828	EPSD;PhosphoSitePlus	COSMIC	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	O14757	CHEK1	O14757	CHEK1	T382	K375R	375	Missense	distal	-7	no	9.696	8.516	EPSD;PhosphoSitePlus	COSMIC	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	O14757	CHEK1	O14757	CHEK1	T382	L384F	384	Missense	proximal	2	no	9.696	9.945	EPSD;PhosphoSitePlus	COSMIC	5.604	Up-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	O14757	CHEK1	O14757	CHEK1	T382	M377I	377	Missense	distal	-5	no	9.696	12.038	EPSD;PhosphoSitePlus	COSMIC	5.604	Up-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	O14757	CHEK1	O14757	CHEK1	T382	K375Q	375	Missense	distal	-7	no	9.696	8.774	EPSD;PhosphoSitePlus	COSMIC	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q14669	TRIP12	O14757	CHEK1	S36	S34I	34	Missense	proximal	-2	no	8.119	8.247	EPSD	COSMIC	5.604	Up-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q14669	TRIP12	O14757	CHEK1	S36	V41M	41	Missense	distal	5	no	8.119	8.092	EPSD	COSMIC	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q14669	TRIP12	O14757	CHEK1	T54	P49Q	49	Missense	distal	-5	no	8.431	9.765	EPSD	COSMIC	5.604	Up-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q14669	TRIP12	O14757	CHEK1	S77	P78L	78	Missense	proximal	1	no	8.888	8.916	EPSD	COSMIC	5.604	Up-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q14669	TRIP12	O14757	CHEK1	S77	N84S	84	Missense	distal	7	no	8.888	8.659	EPSD	COSMIC	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q14669	TRIP12	O14757	CHEK1	S77	R74C	74	Missense	distal	-3	no	8.888	0.797	EPSD	COSMIC	5.604	Loss
CAMK_CAMKL_CHK1_CHEK1_ST	Q14669	TRIP12	O14757	CHEK1	S85	P78L	78	Missense	distal	-7	no	7.771	7.557	EPSD	COSMIC	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q14669	TRIP12	O14757	CHEK1	S85	A89G	89	Missense	distal	4	no	7.771	7.644	EPSD	COSMIC	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q14669	TRIP12	O14757	CHEK1	S85	N84S	84	Missense	proximal	-1	no	7.771	7.553	EPSD	COSMIC	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q14669	TRIP12	O14757	CHEK1	S100	S100F	100	Missense	central	0	yes	9.903	0.000	EPSD	COSMIC	5.604	Loss
CAMK_CAMKL_CHK1_CHEK1_ST	Q14669	TRIP12	O14757	CHEK1	S165	G162R	162	Missense	distal	-3	no	1.491	9.266	EPSD	COSMIC	5.604	Gain
CAMK_CAMKL_CHK1_CHEK1_ST	Q14669	TRIP12	O14757	CHEK1	T192	G189R	189	Missense	distal	-3	no	2.492	10.267	EPSD	COSMIC	5.604	Gain
CAMK_CAMKL_CHK1_CHEK1_ST	Q14669	TRIP12	O14757	CHEK1	S236	P242T	242	Missense	distal	6	no	6.191	5.882	EPSD	COSMIC	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q14669	TRIP12	O14757	CHEK1	S236	K230E	230	Missense	distal	-6	no	6.191	6.160	EPSD	COSMIC	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q14669	TRIP12	O14757	CHEK1	S236	A237T	237	Missense	proximal	1	no	6.191	6.181	EPSD	COSMIC;GDSC;CCLE	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q14669	TRIP12	O14757	CHEK1	S238	P242T	242	Missense	distal	4	no	8.739	8.610	EPSD	COSMIC	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q14669	TRIP12	O14757	CHEK1	S238	A237T	237	Missense	proximal	-1	no	8.739	8.610	EPSD	COSMIC;GDSC;CCLE	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q14669	TRIP12	O14757	CHEK1	S246	P242T	242	Missense	distal	-4	no	8.213	7.926	EPSD	COSMIC	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q14669	TRIP12	O14757	CHEK1	S246	S246N	246	Missense	central	0	yes	8.213	0.000	EPSD	COSMIC	5.604	Loss
CAMK_CAMKL_CHK1_CHEK1_ST	Q14669	TRIP12	O14757	CHEK1	S246	K253E	253	Missense	distal	7	no	8.213	8.379	EPSD	COSMIC	5.604	Up-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q14669	TRIP12	O14757	CHEK1	S340	L342P	342	Missense	proximal	2	no	7.556	7.874	EPSD	COSMIC	5.604	Up-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q14669	TRIP12	O14757	CHEK1	S340	A333S	333	Missense	distal	-7	no	7.556	7.106	EPSD	COSMIC	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q14669	TRIP12	O14757	CHEK1	S340	R337W	337	Missense	distal	-3	no	7.556	-26.047	EPSD	COSMIC	5.604	Loss
CAMK_CAMKL_CHK1_CHEK1_ST	Q14669	TRIP12	O14757	CHEK1	S340	G343C	343	Missense	distal	3	no	7.556	6.694	EPSD	COSMIC	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q14669	TRIP12	O14757	CHEK1	S340	R338L	338	Missense	proximal	-2	no	7.556	7.562	EPSD	COSMIC	5.604	Up-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q14669	TRIP12	O14757	CHEK1	S780	R781W	781	Missense	proximal	1	no	8.069	8.039	EPSD	COSMIC	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q14669	TRIP12	O14757	CHEK1	S780	I778V	778	Missense	proximal	-2	no	8.069	8.132	EPSD	COSMIC	5.604	Up-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q14669	TRIP12	O14757	CHEK1	T1032	S1036P	1036	Missense	distal	4	no	6.788	6.928	EPSD	COSMIC	5.604	Up-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q14669	TRIP12	O14757	CHEK1	T1055	G1051E	1051	Missense	distal	-4	no	10.496	10.673	EPSD	COSMIC	5.604	Up-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q14669	TRIP12	O14757	CHEK1	S1078	N1084S	1084	Missense	distal	6	no	12.866	12.732	PhosphoSitePlus	COSMIC	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q14669	TRIP12	O14757	CHEK1	S1078	K1079E	1079	Missense	proximal	1	no	12.866	12.940	PhosphoSitePlus	COSMIC	5.604	Up-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q14669	TRIP12	O14757	CHEK1	S1146	R1145H	1145	Missense	proximal	-1	no	5.626	5.752	EPSD	COSMIC	5.604	Up-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q14669	TRIP12	O14757	CHEK1	S1367	E1373K	1373	Missense	distal	6	no	8.740	9.010	EPSD	COSMIC	5.604	Up-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q14669	TRIP12	O14757	CHEK1	S1367	R1364W	1364	Missense	distal	-3	no	8.740	-24.863	EPSD	COSMIC	5.604	Loss
CAMK_CAMKL_CHK1_CHEK1_ST	Q14669	TRIP12	O14757	CHEK1	S1376	E1373K	1373	Missense	distal	-3	no	2.906	6.169	EPSD	COSMIC	5.604	Gain
CAMK_CAMKL_CHK1_CHEK1_ST	Q14669	TRIP12	O14757	CHEK1	T1377	E1373K	1373	Missense	distal	-4	no	11.435	11.333	EPSD	COSMIC	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q14669	TRIP12	O14757	CHEK1	T1377	N1382S	1382	Missense	distal	5	no	11.435	11.437	EPSD	COSMIC	5.604	Up-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q14669	TRIP12	O14757	CHEK1	T1377	P1383S	1383	Missense	distal	6	no	11.435	10.816	EPSD	COSMIC	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q14669	TRIP12	O14757	CHEK1	T1377	L1384V	1384	Missense	distal	7	no	11.435	11.572	EPSD	COSMIC	5.604	Up-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q14669	TRIP12	O14757	CHEK1	T1421	Q1420H	1420	Missense	proximal	-1	no	7.001	7.111	EPSD	COSMIC	5.604	Up-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q14669	TRIP12	O14757	CHEK1	T1421	G1414S	1414	Missense	distal	-7	no	7.001	7.222	EPSD	COSMIC	5.604	Up-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q9UKI8	TLK1	O14757	CHEK1	S188	A193T	193	Missense	distal	5	no	9.328	9.087	EPSD	COSMIC	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q9UKI8	TLK1	O14757	CHEK1	S679	N677S	677	Missense	proximal	-2	no	7.733	7.544	EPSD;PhosphoSitePlus	COSMIC	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q9UKI8	TLK1	O14757	CHEK1	S679	L684P	684	Missense	distal	5	no	7.733	7.895	EPSD;PhosphoSitePlus	COSMIC	5.604	Up-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q9UKI8	TLK1	O14757	CHEK1	S679	L684F	684	Missense	distal	5	no	7.733	7.652	EPSD;PhosphoSitePlus	COSMIC	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q9UKI8	TLK1	O14757	CHEK1	S743	R740T	740	Missense	distal	-3	no	8.144	-12.425	PhosphoSitePlus;EPSD	COSMIC	5.604	Loss
CAMK_CAMKL_CHK1_CHEK1_ST	Q9UKI8	TLK1	O14757	CHEK1	S743	R739L	739	Missense	distal	-4	no	8.144	7.888	PhosphoSitePlus;EPSD	COSMIC	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	P49761	CLK3	O14757	CHEK1	S157	S157F	157	Missense	central	0	yes	10.275	0.000	PhosphoSitePlus	COSMIC	5.604	Loss
CAMK_CAMKL_CHK1_CHEK1_ST	P49761	CLK3	O14757	CHEK1	S173	R170K	170	Missense	distal	-3	no	8.724	4.899	EPSD	COSMIC	5.604	Loss
CAMK_CAMKL_CHK1_CHEK1_ST	P49761	CLK3	O14757	CHEK1	S175	R170K	170	Missense	distal	-5	no	8.264	9.440	EPSD	COSMIC	5.604	Up-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	P49761	CLK3	O14757	CHEK1	S186	P192T	192	Missense	distal	6	no	13.199	12.890	EPSD	COSMIC	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	P49761	CLK3	O14757	CHEK1	S197	R198K	198	Missense	proximal	1	no	6.038	6.039	EPSD	COSMIC	5.604	Up-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	P49761	CLK3	O14757	CHEK1	S197	H200N	200	Missense	distal	3	no	6.038	6.852	EPSD	COSMIC	5.604	Up-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	P49761	CLK3	O14757	CHEK1	S197	P192T	192	Missense	distal	-5	no	6.038	8.689	EPSD	COSMIC	5.604	Up-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	P49761	CLK3	O14757	CHEK1	S197	R194T	194	Missense	distal	-3	no	6.038	-14.531	EPSD	COSMIC	5.604	Loss
CAMK_CAMKL_CHK1_CHEK1_ST	P49761	CLK3	O14757	CHEK1	S199	R198K	198	Missense	proximal	-1	no	9.036	8.888	EPSD	COSMIC	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	P49761	CLK3	O14757	CHEK1	S199	H200N	200	Missense	proximal	1	no	9.036	9.073	EPSD	COSMIC	5.604	Up-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	P49761	CLK3	O14757	CHEK1	S199	P192T	192	Missense	distal	-7	no	9.036	8.839	EPSD	COSMIC	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	P49761	CLK3	O14757	CHEK1	S199	R194T	194	Missense	distal	-5	no	9.036	9.957	EPSD	COSMIC	5.604	Up-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	P49761	CLK3	O14757	CHEK1	S215	R219W	219	Missense	distal	4	no	9.322	9.385	EPSD	COSMIC	5.604	Up-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	P49761	CLK3	O14757	CHEK1	S226	E229D	229	Missense	distal	3	no	9.928	10.025	EPSD	COSMIC	5.604	Up-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	P49761	CLK3	O14757	CHEK1	S226	R219W	219	Missense	distal	-7	no	9.928	8.382	EPSD	COSMIC	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	P49761	CLK3	O14757	CHEK1	S243	R236H	236	Missense	distal	-7	no	9.239	9.180	EPSD	COSMIC	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	P49761	CLK3	O14757	CHEK1	S243	R242L	242	Missense	proximal	-1	no	9.239	9.338	EPSD	COSMIC	5.604	Up-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	P49761	CLK3	O14757	CHEK1	S243	R236C	236	Missense	distal	-7	no	9.239	8.511	EPSD	COSMIC	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	P49761	CLK3	O14757	CHEK1	S243	R238P	238	Missense	distal	-5	no	9.239	7.509	EPSD	COSMIC	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	P49761	CLK3	O14757	CHEK1	S243	R250Q	250	Missense	distal	7	no	9.239	9.394	EPSD	COSMIC	5.604	Up-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	P49761	CLK3	O14757	CHEK1	S243	S243L	243	Missense	central	0	yes	9.239	0.000	EPSD	COSMIC	5.604	Loss
CAMK_CAMKL_CHK1_CHEK1_ST	P49761	CLK3	O14757	CHEK1	S243	R238H	238	Missense	distal	-5	no	9.239	6.774	EPSD	COSMIC	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	P49761	CLK3	O14757	CHEK1	S265	R261C	261	Missense	distal	-4	no	10.395	10.022	EPSD	COSMIC	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	P49761	CLK3	O14757	CHEK1	S267	R261C	261	Missense	distal	-6	no	8.524	8.640	EPSD	COSMIC	5.604	Up-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	P49761	CLK3	O14757	CHEK1	S463	T462A	462	Missense	proximal	-1	no	6.624	6.753	EPSD	COSMIC	5.604	Up-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	P49761	CLK3	O14757	CHEK1	S463	K457E	457	Missense	distal	-6	no	6.624	6.592	EPSD	COSMIC	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	P49761	CLK3	O14757	CHEK1	S463	K457N	457	Missense	distal	-6	no	6.624	6.756	EPSD	COSMIC	5.604	Up-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	P49761	CLK3	O14757	CHEK1	S637	T632P	632	Missense	distal	-5	no	6.277	3.626	EPSD	COSMIC	5.604	Loss
CAMK_CAMKL_CHK1_CHEK1_ST	Q53H47	SETMAR	O14757	CHEK1	S508	R507Q	507	Missense	proximal	-1	no	9.479	9.494	PhosphoSitePlus	COSMIC	5.604	Up-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	P85299	PRR5	O14757	CHEK1	S11	R5W	5	Missense	distal	-6	no	5.730	6.050	EPSD	COSMIC	5.604	Up-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	P85299	PRR5	O14757	CHEK1	S11	L18P	18	Missense	distal	7	no	5.730	5.793	EPSD	COSMIC	5.604	Up-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	P85299	PRR5	O14757	CHEK1	S240	R237H	237	Missense	distal	-3	no	12.950	7.141	PhosphoSitePlus	COSMIC	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	P85299	PRR5	O14757	CHEK1	S240	V243M	243	Missense	distal	3	no	12.950	12.524	PhosphoSitePlus	COSMIC	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	P85299	PRR5	O14757	CHEK1	S240	V243L	243	Missense	distal	3	no	12.950	12.178	PhosphoSitePlus	COSMIC	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	P85299	PRR5	O14757	CHEK1	S240	R236C	236	Missense	distal	-4	no	12.950	12.577	PhosphoSitePlus	COSMIC	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	P85299	PRR5	O14757	CHEK1	S240	R236L	236	Missense	distal	-4	no	12.950	12.695	PhosphoSitePlus	COSMIC	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	P85299	PRR5	O14757	CHEK1	S240	R236F	236	Missense	distal	-4	no	12.950	12.400	PhosphoSitePlus	COSMIC	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	P85299	PRR5	O14757	CHEK1	S240	G241R	241	Missense	proximal	1	no	12.950	12.959	PhosphoSitePlus	COSMIC	5.604	Up-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	P85299	PRR5	O14757	CHEK1	S240	L244P	244	Missense	distal	4	no	12.950	13.054	PhosphoSitePlus	COSMIC	5.604	Up-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	P85299	PRR5	O14757	CHEK1	S240	N247K	247	Missense	distal	7	no	12.950	12.889	PhosphoSitePlus	COSMIC	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	P85299	PRR5	O14757	CHEK1	S240	R233L	233	Missense	distal	-7	no	12.950	12.326	PhosphoSitePlus	COSMIC	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	P85299	PRR5	O14757	CHEK1	S240	L235F	235	Missense	distal	-5	no	12.950	9.387	PhosphoSitePlus	COSMIC	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	P85299	PRR5	O14757	CHEK1	S254	T257M	257	Missense	distal	3	no	9.157	9.213	EPSD	COSMIC	5.604	Up-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	P85299	PRR5	O14757	CHEK1	S254	R251G	251	Missense	distal	-3	no	9.157	1.382	EPSD	COSMIC	5.604	Loss
CAMK_CAMKL_CHK1_CHEK1_ST	P85299	PRR5	O14757	CHEK1	S254	N247K	247	Missense	distal	-7	no	9.157	10.615	EPSD	COSMIC	5.604	Up-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	P85299	PRR5	O14757	CHEK1	S282	R280S	280	Missense	proximal	-2	no	9.869	9.770	EPSD	COSMIC	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	P85299	PRR5	O14757	CHEK1	S282	R280M	280	Missense	proximal	-2	no	9.869	9.912	EPSD	COSMIC	5.604	Up-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	P85299	PRR5	O14757	CHEK1	S282	V283M	283	Missense	proximal	1	no	9.869	9.861	EPSD	COSMIC	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	P85299	PRR5	O14757	CHEK1	S282	G275S	275	Missense	distal	-7	no	9.869	10.090	EPSD	COSMIC	5.604	Up-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	O75461	E2F6	O14757	CHEK1	S52	Y50F	50	Missense	proximal	-2	no	6.974	7.152	PhosphoSitePlus;EPSD	COSMIC	5.604	Up-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	O75461	E2F6	O14757	CHEK1	S52	M53I	53	Missense	proximal	1	no	6.974	6.953	PhosphoSitePlus;EPSD	COSMIC	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	P04637	TP53	O14757	CHEK1	S37	M40I	40	Missense	distal	3	no	8.422	8.135	PhosphoSitePlus;EPSD	COSMIC	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	P04637	TP53	O14757	CHEK1	S37	V31I	31	Missense	distal	-6	no	8.422	8.409	PhosphoSitePlus;EPSD	COSMIC;GDSC;CCLE	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	P04637	TP53	O14757	CHEK1	S37	P36L	36	Missense	proximal	-1	no	8.422	8.236	PhosphoSitePlus;EPSD	COSMIC;GDSC;CCLE	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	P04637	TP53	O14757	CHEK1	S37	S33T	33	Missense	distal	-4	no	8.422	8.371	PhosphoSitePlus;EPSD	COSMIC	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	P04637	TP53	O14757	CHEK1	S37	D41N	41	Missense	distal	4	no	8.422	8.392	PhosphoSitePlus;EPSD	COSMIC	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	P04637	TP53	O14757	CHEK1	S37	L35F	35	Missense	proximal	-2	no	8.422	8.607	PhosphoSitePlus;EPSD	COSMIC	5.604	Up-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	P04637	TP53	O14757	CHEK1	S37	Q38L	38	Missense	proximal	1	no	8.422	8.379	PhosphoSitePlus;EPSD	COSMIC	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	P04637	TP53	O14757	CHEK1	S37	M44I	44	Missense	distal	7	no	8.422	8.146	PhosphoSitePlus;EPSD	COSMIC	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	P04637	TP53	O14757	CHEK1	S37	P36S	36	Missense	proximal	-1	no	8.422	7.975	PhosphoSitePlus;EPSD	COSMIC;GDSC;CCLE	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	P04637	TP53	O14757	CHEK1	S37	A39V	39	Missense	proximal	2	no	8.422	7.859	PhosphoSitePlus;EPSD	COSMIC	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	P04637	TP53	O14757	CHEK1	S37	A39S	39	Missense	proximal	2	no	8.422	7.966	PhosphoSitePlus;EPSD	COSMIC	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	P04637	TP53	O14757	CHEK1	S37	D42Y	42	Missense	distal	5	no	8.422	7.881	PhosphoSitePlus;EPSD	COSMIC	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	P04637	TP53	O14757	CHEK1	S37	M44R	44	Missense	distal	7	no	8.422	8.530	PhosphoSitePlus;EPSD	COSMIC	5.604	Up-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	P04637	TP53	O14757	CHEK1	S37	M44V	44	Missense	distal	7	no	8.422	8.566	PhosphoSitePlus;EPSD	COSMIC	5.604	Up-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	P04637	TP53	O14757	CHEK1	S37	N30K	30	Missense	distal	-7	no	8.422	9.880	PhosphoSitePlus;EPSD	COSMIC	5.604	Up-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	P04637	TP53	O14757	CHEK1	S37	M44T	44	Missense	distal	7	no	8.422	8.371	PhosphoSitePlus;EPSD	COSMIC	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	P04637	TP53	O14757	CHEK1	S37	A39T	39	Missense	proximal	2	no	8.422	7.574	PhosphoSitePlus;EPSD	COSMIC	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	P04637	TP53	O14757	CHEK1	S37	L43F	43	Missense	distal	6	no	8.422	8.416	PhosphoSitePlus;EPSD	COSMIC	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	P04637	TP53	O14757	CHEK1	S37	D41H	41	Missense	distal	4	no	8.422	8.584	PhosphoSitePlus;EPSD	COSMIC	5.604	Up-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	P04637	TP53	O14757	CHEK1	S37	P36R	36	Missense	proximal	-1	no	8.422	8.137	PhosphoSitePlus;EPSD	COSMIC	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	P04637	TP53	O14757	CHEK1	S37	L35R	35	Missense	proximal	-2	no	8.422	8.416	PhosphoSitePlus;EPSD	COSMIC	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	P04637	TP53	O14757	CHEK1	S37	L35H	35	Missense	proximal	-2	no	8.422	8.481	PhosphoSitePlus;EPSD	COSMIC	5.604	Up-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	P04637	TP53	O14757	CHEK1	S37	L35P	35	Missense	proximal	-2	no	8.422	8.601	PhosphoSitePlus;EPSD	COSMIC	5.604	Up-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	P04637	TP53	O14757	CHEK1	S37	L35I	35	Missense	proximal	-2	no	8.422	8.445	PhosphoSitePlus;EPSD	COSMIC	5.604	Up-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	P04637	TP53	O14757	CHEK1	S37	L35V	35	Missense	proximal	-2	no	8.422	8.509	PhosphoSitePlus;EPSD	COSMIC	5.604	Up-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	P04637	TP53	O14757	CHEK1	S37	D41E	41	Missense	distal	4	no	8.422	8.330	PhosphoSitePlus;EPSD	COSMIC	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	P04637	TP53	O14757	CHEK1	S127	V122L	122	Missense	distal	-5	no	2.181	5.657	EPSD	COSMIC	5.604	Gain
CAMK_CAMKL_CHK1_CHEK1_ST	P04637	TP53	O14757	CHEK1	S149	W146R	146	Missense	distal	-3	no	-26.325	7.278	EPSD	COSMIC	5.604	Gain
CAMK_CAMKL_CHK1_CHEK1_ST	P04637	TP53	O14757	CHEK1	S183	H178L	178	Missense	distal	-5	no	2.591	8.033	EPSD	COSMIC	5.604	Gain
CAMK_CAMKL_CHK1_CHEK1_ST	P04637	TP53	O14757	CHEK1	T211	D208H	208	Missense	distal	-3	no	3.066	6.593	EPSD	COSMIC	5.604	Gain
CAMK_CAMKL_CHK1_CHEK1_ST	P04637	TP53	O14757	CHEK1	S269	G266A	266	Missense	distal	-3	no	5.247	6.310	EPSD	COSMIC	5.604	Gain
CAMK_CAMKL_CHK1_CHEK1_ST	P04637	TP53	O14757	CHEK1	S269	G266K	266	Missense	distal	-3	no	5.247	9.196	EPSD	COSMIC	5.604	Gain
CAMK_CAMKL_CHK1_CHEK1_ST	P04637	TP53	O14757	CHEK1	S269	L265Q	265	Missense	distal	-4	no	5.247	5.663	EPSD	COSMIC	5.604	Gain
CAMK_CAMKL_CHK1_CHEK1_ST	P04637	TP53	O14757	CHEK1	T284	D281R	281	Missense	distal	-3	no	-1.807	7.530	EPSD	COSMIC	5.604	Gain
CAMK_CAMKL_CHK1_CHEK1_ST	P04637	TP53	O14757	CHEK1	T312	A307T	307	Missense	distal	-5	no	1.918	5.778	EPSD	COSMIC	5.604	Gain
CAMK_CAMKL_CHK1_CHEK1_ST	P04637	TP53	O14757	CHEK1	T312	P309R	309	Missense	distal	-3	no	1.918	9.055	EPSD	COSMIC	5.604	Gain
CAMK_CAMKL_CHK1_CHEK1_ST	P04637	TP53	O14757	CHEK1	S366	S367F	367	Missense	proximal	1	no	7.200	7.195	EPSD	COSMIC	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	P04637	TP53	O14757	CHEK1	S366	K370N	370	Missense	distal	4	no	7.200	7.267	EPSD	COSMIC	5.604	Up-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	P04637	TP53	O14757	CHEK1	S366	G361E	361	Missense	distal	-5	no	7.200	5.979	EPSD	COSMIC	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	P04637	TP53	O14757	CHEK1	S366	P359S	359	Missense	distal	-7	no	7.200	7.870	EPSD	COSMIC	5.604	Up-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	P04637	TP53	O14757	CHEK1	S366	A364D	364	Missense	proximal	-2	no	7.200	7.132	EPSD	COSMIC	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	P04637	TP53	O14757	CHEK1	S366	H365Y	365	Missense	proximal	-1	no	7.200	7.242	EPSD	COSMIC	5.604	Up-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	P04637	TP53	O14757	CHEK1	S366	G360A	360	Missense	distal	-6	no	7.200	7.036	EPSD	COSMIC	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	P04637	TP53	O14757	CHEK1	S366	A364T	364	Missense	proximal	-2	no	7.200	7.339	EPSD	COSMIC	5.604	Up-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	P04637	TP53	O14757	CHEK1	S366	S366A	366	Missense	central	0	yes	7.200	0.000	EPSD	COSMIC	5.604	Loss
CAMK_CAMKL_CHK1_CHEK1_ST	P04637	TP53	O14757	CHEK1	S366	G361R	361	Missense	distal	-5	no	7.200	7.365	EPSD	COSMIC	5.604	Up-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	P04637	TP53	O14757	CHEK1	S366	K370Q	370	Missense	distal	4	no	7.200	7.297	EPSD	COSMIC	5.604	Up-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	P04637	TP53	O14757	CHEK1	S366	K373R	373	Missense	distal	7	no	7.200	7.124	EPSD	COSMIC	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	P04637	TP53	O14757	CHEK1	S366	S371P	371	Missense	distal	5	no	7.200	7.118	EPSD	COSMIC	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	P04637	TP53	O14757	CHEK1	S376	K373R	373	Missense	distal	-3	no	2.992	6.817	EPSD	COSMIC	5.604	Gain
CAMK_CAMKL_CHK1_CHEK1_ST	O15350	TP73	O14757	CHEK1	S426	V427I	427	Missense	proximal	1	no	6.018	5.988	EPSD	COSMIC;CCLE	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q12789	GTF3C1	O14757	CHEK1	S480	R484G	484	Missense	distal	4	no	6.209	6.226	EPSD	COSMIC	5.604	Up-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q12789	GTF3C1	O14757	CHEK1	T508	N503K	503	Missense	distal	-5	no	7.593	8.487	EPSD	COSMIC	5.604	Up-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q12789	GTF3C1	O14757	CHEK1	S546	E541K	541	Missense	distal	-5	no	3.504	6.065	EPSD	COSMIC	5.604	Gain
CAMK_CAMKL_CHK1_CHEK1_ST	Q12789	GTF3C1	O14757	CHEK1	S667	V660F	660	Missense	distal	-7	no	13.699	12.173	PhosphoSitePlus	COSMIC	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q12789	GTF3C1	O14757	CHEK1	S667	R664L	664	Missense	distal	-3	no	13.699	-4.848	PhosphoSitePlus	COSMIC	5.604	Loss
CAMK_CAMKL_CHK1_CHEK1_ST	Q12789	GTF3C1	O14757	CHEK1	S667	V663M	663	Missense	distal	-4	no	13.699	13.543	PhosphoSitePlus	COSMIC	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q12789	GTF3C1	O14757	CHEK1	S667	R673Q	673	Missense	distal	6	no	13.699	13.692	PhosphoSitePlus	COSMIC	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q12789	GTF3C1	O14757	CHEK1	S667	S667Y	667	Missense	central	0	yes	13.699	0.000	PhosphoSitePlus	COSMIC	5.604	Loss
CAMK_CAMKL_CHK1_CHEK1_ST	Q12789	GTF3C1	O14757	CHEK1	S695	P694T	694	Missense	proximal	-1	no	7.572	7.329	EPSD	COSMIC	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q12789	GTF3C1	O14757	CHEK1	S695	P694L	694	Missense	proximal	-1	no	7.572	7.385	EPSD	COSMIC	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q12789	GTF3C1	O14757	CHEK1	T725	P728A	728	Missense	distal	3	no	7.270	7.034	EPSD	COSMIC	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q12789	GTF3C1	O14757	CHEK1	T725	R722M	722	Missense	distal	-3	no	7.270	2.121	EPSD	COSMIC	5.604	Loss
CAMK_CAMKL_CHK1_CHEK1_ST	Q12789	GTF3C1	O14757	CHEK1	S761	G762E	762	Missense	proximal	1	no	7.852	7.935	EPSD	COSMIC;CCLE	5.604	Up-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q12789	GTF3C1	O14757	CHEK1	S761	R763W	763	Missense	proximal	2	no	7.852	7.678	EPSD	COSMIC	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q12789	GTF3C1	O14757	CHEK1	S836	V841L	841	Missense	distal	5	no	7.266	7.107	EPSD	COSMIC;GDSC;CCLE	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q12789	GTF3C1	O14757	CHEK1	S845	V841L	841	Missense	distal	-4	no	6.410	6.162	EPSD	COSMIC;GDSC;CCLE	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q12789	GTF3C1	O14757	CHEK1	S1062	D1069V	1069	Missense	distal	7	no	11.732	11.470	EPSD	COSMIC	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q12789	GTF3C1	O14757	CHEK1	S1063	D1069V	1069	Missense	distal	6	no	7.279	7.739	EPSD	COSMIC	5.604	Up-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q12789	GTF3C1	O14757	CHEK1	S1173	R1170T	1170	Missense	distal	-3	no	9.124	-11.445	EPSD	COSMIC;CCLE	5.604	Loss
CAMK_CAMKL_CHK1_CHEK1_ST	Q12789	GTF3C1	O14757	CHEK1	S1173	N1172S	1172	Missense	proximal	-1	no	9.124	8.905	EPSD	COSMIC	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q12789	GTF3C1	O14757	CHEK1	S1173	S1168G	1168	Missense	distal	-5	no	9.124	9.170	EPSD	COSMIC;GDSC;CCLE	5.604	Up-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q12789	GTF3C1	O14757	CHEK1	S1202	N1206T	1206	Missense	distal	4	no	9.980	9.971	EPSD	COSMIC	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q12789	GTF3C1	O14757	CHEK1	S1202	R1207W	1207	Missense	distal	5	no	9.980	9.812	EPSD	COSMIC	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q12789	GTF3C1	O14757	CHEK1	S1202	R1205Q	1205	Missense	distal	3	no	9.980	11.042	EPSD	COSMIC	5.604	Up-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q12789	GTF3C1	O14757	CHEK1	S1202	V1209L	1209	Missense	distal	7	no	9.980	9.844	EPSD	COSMIC	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q12789	GTF3C1	O14757	CHEK1	S1379	S1379I	1379	Missense	central	0	yes	7.706	0.000	EPSD	COSMIC	5.604	Loss
CAMK_CAMKL_CHK1_CHEK1_ST	Q12789	GTF3C1	O14757	CHEK1	S1379	A1381V	1381	Missense	proximal	2	no	7.706	7.143	EPSD	COSMIC	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q12789	GTF3C1	O14757	CHEK1	S1379	R1383K	1383	Missense	distal	4	no	7.706	7.608	EPSD	COSMIC	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q12789	GTF3C1	O14757	CHEK1	S1379	R1383S	1383	Missense	distal	4	no	7.706	7.656	EPSD	COSMIC	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q12789	GTF3C1	O14757	CHEK1	S1380	S1379I	1379	Missense	proximal	-1	no	10.872	10.989	EPSD	COSMIC	5.604	Up-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q12789	GTF3C1	O14757	CHEK1	S1380	A1381V	1381	Missense	proximal	1	no	10.872	10.847	EPSD	COSMIC	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q12789	GTF3C1	O14757	CHEK1	S1380	R1383K	1383	Missense	distal	3	no	10.872	11.518	EPSD	COSMIC	5.604	Up-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q12789	GTF3C1	O14757	CHEK1	S1380	R1383S	1383	Missense	distal	3	no	10.872	10.874	EPSD	COSMIC	5.604	Up-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q12789	GTF3C1	O14757	CHEK1	S1641	K1636R	1636	Missense	distal	-5	no	6.862	5.686	EPSD	COSMIC	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q12789	GTF3C1	O14757	CHEK1	S1767	R1765W	1765	Missense	proximal	-2	no	13.121	13.243	EPSD	COSMIC	5.604	Up-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q12789	GTF3C1	O14757	CHEK1	S1865	S1868G	1868	Missense	distal	3	no	10.048	9.961	EPSD	COSMIC	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q5T8P6	RBM26	O14757	CHEK1	S186	R193C	193	Missense	distal	7	no	9.794	9.389	EPSD	COSMIC	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q5T8P6	RBM26	O14757	CHEK1	S186	R193H	193	Missense	distal	7	no	9.794	9.501	EPSD	COSMIC	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q5T8P6	RBM26	O14757	CHEK1	S188	R193C	193	Missense	distal	5	no	9.428	9.184	EPSD	COSMIC	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q5T8P6	RBM26	O14757	CHEK1	S188	R193H	193	Missense	distal	5	no	9.428	9.444	EPSD	COSMIC	5.604	Up-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q5T8P6	RBM26	O14757	CHEK1	T493	G500S	500	Missense	distal	7	no	5.819	5.720	EPSD	COSMIC	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q5T8P6	RBM26	O14757	CHEK1	S518	N517I	517	Missense	proximal	-1	no	7.708	7.607	EPSD	COSMIC;GDSC	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q5T8P6	RBM26	O14757	CHEK1	S608	E606D	606	Missense	proximal	-2	no	7.751	7.737	EPSD	COSMIC	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q5T8P6	RBM26	O14757	CHEK1	S689	S689Y	689	Missense	central	0	yes	6.947	0.000	EPSD	COSMIC	5.604	Loss
CAMK_CAMKL_CHK1_CHEK1_ST	Q5T8P6	RBM26	O14757	CHEK1	S689	L694V	694	Missense	distal	5	no	6.947	7.106	EPSD	COSMIC	5.604	Up-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q5T8P6	RBM26	O14757	CHEK1	S689	G693S	693	Missense	distal	4	no	6.947	6.880	EPSD	COSMIC	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q5T8P6	RBM26	O14757	CHEK1	S795	D789N	789	Missense	distal	-6	no	5.513	5.726	EPSD	COSMIC	5.604	Gain
CAMK_CAMKL_CHK1_CHEK1_ST	Q5T8P6	RBM26	O14757	CHEK1	S795	D789H	789	Missense	distal	-6	no	5.513	5.715	EPSD	COSMIC	5.604	Gain
CAMK_CAMKL_CHK1_CHEK1_ST	Q5T8P6	RBM26	O14757	CHEK1	S795	L800V	800	Missense	distal	5	no	5.513	5.672	EPSD	COSMIC	5.604	Gain
CAMK_CAMKL_CHK1_CHEK1_ST	Q5T8P6	RBM26	O14757	CHEK1	S795	G797E	797	Missense	proximal	2	no	5.513	6.127	EPSD	COSMIC	5.604	Gain
CAMK_CAMKL_CHK1_CHEK1_ST	Q5T8P6	RBM26	O14757	CHEK1	S795	E790K	790	Missense	distal	-5	no	5.513	8.075	EPSD	COSMIC	5.604	Gain
CAMK_CAMKL_CHK1_CHEK1_ST	Q5T8P6	RBM26	O14757	CHEK1	T839	T839A	839	Missense	central	0	yes	12.756	0.000	PhosphoSitePlus	COSMIC	5.604	Loss
CAMK_CAMKL_CHK1_CHEK1_ST	Q5T8P6	RBM26	O14757	CHEK1	T839	E833D	833	Missense	distal	-6	no	12.756	12.706	PhosphoSitePlus	COSMIC	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	P16989	YBX3	O14757	CHEK1	T112	E114D	114	Missense	proximal	2	no	11.798	11.715	PhosphoSitePlus	COSMIC	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	P16989	YBX3	O14757	CHEK1	T112	G105E	105	Missense	distal	-7	no	11.798	12.242	PhosphoSitePlus	COSMIC	5.604	Up-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	P16989	YBX3	O14757	CHEK1	T112	R109Q	109	Missense	distal	-3	no	11.798	4.591	PhosphoSitePlus	COSMIC	5.604	Loss
CAMK_CAMKL_CHK1_CHEK1_ST	P16989	YBX3	O14757	CHEK1	S203	E198D	198	Missense	distal	-5	no	6.827	7.227	EPSD	COSMIC	5.604	Up-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	P16989	YBX3	O14757	CHEK1	S217	R224C	224	Missense	distal	7	no	9.466	9.061	EPSD	COSMIC	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	P16989	YBX3	O14757	CHEK1	S217	R224H	224	Missense	distal	7	no	9.466	9.173	EPSD	COSMIC	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	P16989	YBX3	O14757	CHEK1	S217	R220W	220	Missense	distal	3	no	9.466	9.328	EPSD	COSMIC;CCLE	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	P16989	YBX3	O14757	CHEK1	S217	R214Q	214	Missense	distal	-3	no	9.466	2.259	EPSD	COSMIC	5.604	Loss
CAMK_CAMKL_CHK1_CHEK1_ST	P16989	YBX3	O14757	CHEK1	S217	A219P	219	Missense	proximal	2	no	9.466	8.933	EPSD	COSMIC	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	P16989	YBX3	O14757	CHEK1	T286	R292C	292	Missense	distal	6	no	6.117	6.410	EPSD	COSMIC	5.604	Up-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	P16989	YBX3	O14757	CHEK1	T286	R283Q	283	Missense	distal	-3	no	6.117	-1.090	EPSD	COSMIC	5.604	Loss
CAMK_CAMKL_CHK1_CHEK1_ST	P16989	YBX3	O14757	CHEK1	S293	R292C	292	Missense	proximal	-1	no	11.199	11.234	EPSD	COSMIC	5.604	Up-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q27J81	INF2	O14757	CHEK1	S129	V125M	125	Missense	distal	-4	no	9.006	8.851	EPSD	COSMIC	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q27J81	INF2	O14757	CHEK1	S343	S343F	343	Missense	central	0	yes	10.055	0.000	EPSD	COSMIC	5.604	Loss
CAMK_CAMKL_CHK1_CHEK1_ST	Q27J81	INF2	O14757	CHEK1	S574	S574F	574	Missense	central	0	yes	7.239	0.000	PhosphoSitePlus	COSMIC;GDSC;CCLE	5.604	Loss
CAMK_CAMKL_CHK1_CHEK1_ST	Q27J81	INF2	O14757	CHEK1	S586	D591G	591	Missense	distal	5	no	7.871	7.593	EPSD	COSMIC	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q27J81	INF2	O14757	CHEK1	S607	P609S	609	Missense	proximal	2	no	8.081	8.158	EPSD	COSMIC	5.604	Up-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q27J81	INF2	O14757	CHEK1	S855	E860K	860	Missense	distal	5	no	12.364	12.298	EPSD	COSMIC;GDSC;CCLE	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q27J81	INF2	O14757	CHEK1	S1077	R1070W	1070	Missense	distal	-7	no	12.154	10.609	EPSD	COSMIC	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q27J81	INF2	O14757	CHEK1	S1077	P1071L	1071	Missense	distal	-6	no	12.154	12.081	EPSD	COSMIC	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q27J81	INF2	O14757	CHEK1	S1194	E1195K	1195	Missense	proximal	1	no	8.336	8.262	EPSD	COSMIC	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q27J81	INF2	O14757	CHEK1	S1229	D1236G	1236	Missense	distal	7	no	6.137	5.844	EPSD	COSMIC	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	P30304	CDC25A	O14757	CHEK1	S76	N70H	70	Missense	distal	-6	no	13.331	13.319	PhosphoSitePlus;EPSD	COSMIC	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	P30304	CDC25A	O14757	CHEK1	S76	S69G	69	Missense	distal	-7	no	13.331	13.110	PhosphoSitePlus;EPSD	COSMIC	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	P30304	CDC25A	O14757	CHEK1	S124	D128G	128	Missense	distal	4	no	10.290	10.306	EPSD;PhosphoSitePlus	COSMIC	5.604	Up-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	P30304	CDC25A	O14757	CHEK1	S178	L184F	184	Missense	distal	6	no	11.553	11.546	EPSD;PhosphoSitePlus	COSMIC	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	P30304	CDC25A	O14757	CHEK1	S293	S293N	293	Missense	central	0	yes	9.771	0.000	EPSD;PhosphoSitePlus	COSMIC	5.604	Loss
CAMK_CAMKL_CHK1_CHEK1_ST	P30304	CDC25A	O14757	CHEK1	S505	S505R	505	Missense	central	0	yes	7.469	0.000	EPSD	COSMIC	5.604	Loss
CAMK_CAMKL_CHK1_CHEK1_ST	P30304	CDC25A	O14757	CHEK1	S505	K500N	500	Missense	distal	-5	no	7.469	6.575	EPSD	COSMIC	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	P30304	CDC25A	O14757	CHEK1	T507	S505R	505	Missense	proximal	-2	no	6.453	6.552	EPSD;PhosphoSitePlus	COSMIC	5.604	Up-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	P30304	CDC25A	O14757	CHEK1	T507	K500N	500	Missense	distal	-7	no	6.453	4.995	EPSD;PhosphoSitePlus	COSMIC	5.604	Loss
CAMK_CAMKL_CHK1_CHEK1_ST	P46013	MKI67	O14757	CHEK1	T109	F111L	111	Missense	proximal	2	no	7.616	7.366	EPSD	COSMIC	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	P46013	MKI67	O14757	CHEK1	S125	R123H	123	Missense	proximal	-2	no	7.054	7.119	EPSD	COSMIC	5.604	Up-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	P46013	MKI67	O14757	CHEK1	S125	S130C	130	Missense	distal	5	no	7.054	6.707	EPSD	COSMIC	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	P46013	MKI67	O14757	CHEK1	S166	D165N	165	Missense	proximal	-1	no	8.077	8.166	EPSD	COSMIC	5.604	Up-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	P46013	MKI67	O14757	CHEK1	S166	T167I	167	Missense	proximal	1	no	8.077	8.034	EPSD	COSMIC	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	P46013	MKI67	O14757	CHEK1	S166	K160N	160	Missense	distal	-6	no	8.077	8.209	EPSD	COSMIC	5.604	Up-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	P46013	MKI67	O14757	CHEK1	S166	D170E	170	Missense	distal	4	no	8.077	7.985	EPSD	COSMIC	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	P46013	MKI67	O14757	CHEK1	S296	G300V	300	Missense	distal	4	no	11.621	11.665	EPSD	COSMIC	5.604	Up-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	P46013	MKI67	O14757	CHEK1	S296	H301Y	301	Missense	distal	5	no	11.621	11.254	EPSD	COSMIC	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	P46013	MKI67	O14757	CHEK1	T389	G386A	386	Missense	distal	-3	no	5.250	6.313	EPSD	COSMIC	5.604	Gain
CAMK_CAMKL_CHK1_CHEK1_ST	P46013	MKI67	O14757	CHEK1	T391	G386A	386	Missense	distal	-5	no	5.729	2.954	EPSD	COSMIC	5.604	Loss
CAMK_CAMKL_CHK1_CHEK1_ST	P46013	MKI67	O14757	CHEK1	T391	T389S	389	Missense	proximal	-2	no	5.729	5.475	EPSD	COSMIC	5.604	Loss
CAMK_CAMKL_CHK1_CHEK1_ST	P46013	MKI67	O14757	CHEK1	T391	G386S	386	Missense	distal	-5	no	5.729	5.683	EPSD	COSMIC;GDSC;CCLE	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	P46013	MKI67	O14757	CHEK1	S396	T389S	389	Missense	distal	-7	no	9.227	10.094	EPSD	COSMIC	5.604	Up-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	P46013	MKI67	O14757	CHEK1	S396	P402T	402	Missense	distal	6	no	9.227	8.919	EPSD	COSMIC	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	P46013	MKI67	O14757	CHEK1	T401	E406G	406	Missense	distal	5	no	9.023	8.747	EPSD	COSMIC	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	P46013	MKI67	O14757	CHEK1	T401	E406K	406	Missense	distal	5	no	9.023	8.958	EPSD	COSMIC	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	P46013	MKI67	O14757	CHEK1	T401	P402T	402	Missense	proximal	1	no	9.023	9.068	EPSD	COSMIC	5.604	Up-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	P46013	MKI67	O14757	CHEK1	S507	R505C	505	Missense	proximal	-2	no	9.465	9.414	EPSD	COSMIC	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	P46013	MKI67	O14757	CHEK1	S507	R505H	505	Missense	proximal	-2	no	9.465	9.530	EPSD	COSMIC;GDSC	5.604	Up-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	P46013	MKI67	O14757	CHEK1	S558	E553K	553	Missense	distal	-5	no	3.293	5.855	EPSD	COSMIC	5.604	Gain
CAMK_CAMKL_CHK1_CHEK1_ST	P46013	MKI67	O14757	CHEK1	S598	R596S	596	Missense	proximal	-2	no	9.987	9.888	EPSD	COSMIC	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	P46013	MKI67	O14757	CHEK1	S598	A604V	604	Missense	distal	6	no	9.987	9.875	EPSD	COSMIC;CCLE	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	P46013	MKI67	O14757	CHEK1	S598	R595H	595	Missense	distal	-3	no	9.987	4.178	EPSD	COSMIC	5.604	Loss
CAMK_CAMKL_CHK1_CHEK1_ST	P46013	MKI67	O14757	CHEK1	S660	A662T	662	Missense	proximal	2	no	7.377	6.529	EPSD	COSMIC	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	P46013	MKI67	O14757	CHEK1	T694	T694M	694	Missense	central	0	yes	10.172	0.000	EPSD	COSMIC	5.604	Loss
CAMK_CAMKL_CHK1_CHEK1_ST	P46013	MKI67	O14757	CHEK1	T708	Q705R	705	Missense	distal	-3	no	-1.164	6.043	EPSD	COSMIC	5.604	Gain
CAMK_CAMKL_CHK1_CHEK1_ST	P46013	MKI67	O14757	CHEK1	S713	H710R	710	Missense	distal	-3	no	4.435	10.245	EPSD	COSMIC;GDSC;CCLE	5.604	Gain
CAMK_CAMKL_CHK1_CHEK1_ST	P46013	MKI67	O14757	CHEK1	S793	G790E	790	Missense	distal	-3	no	5.356	6.042	EPSD	COSMIC	5.604	Gain
CAMK_CAMKL_CHK1_CHEK1_ST	P46013	MKI67	O14757	CHEK1	S853	L854V	854	Missense	proximal	1	no	9.469	9.472	EPSD	COSMIC	5.604	Up-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	P46013	MKI67	O14757	CHEK1	S853	S853Y	853	Missense	central	0	yes	9.469	0.000	EPSD	COSMIC;GDSC;CCLE	5.604	Loss
CAMK_CAMKL_CHK1_CHEK1_ST	P46013	MKI67	O14757	CHEK1	S853	K857Q	857	Missense	distal	4	no	9.469	9.567	EPSD	COSMIC	5.604	Up-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	P46013	MKI67	O14757	CHEK1	S853	K857E	857	Missense	distal	4	no	9.469	9.475	EPSD	COSMIC	5.604	Up-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	P46013	MKI67	O14757	CHEK1	T1335	E1338Q	1338	Missense	distal	3	no	9.811	9.411	EPSD	COSMIC	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	P46013	MKI67	O14757	CHEK1	T1335	P1333L	1333	Missense	proximal	-2	no	9.811	9.632	EPSD	COSMIC	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	P46013	MKI67	O14757	CHEK1	T1335	T1335A	1335	Missense	central	0	yes	9.811	0.000	EPSD	COSMIC	5.604	Loss
CAMK_CAMKL_CHK1_CHEK1_ST	P46013	MKI67	O14757	CHEK1	S1405	V1400L	1400	Missense	distal	-5	no	5.388	8.864	EPSD	COSMIC	5.604	Gain
CAMK_CAMKL_CHK1_CHEK1_ST	P46013	MKI67	O14757	CHEK1	S1533	R1530Q	1530	Missense	distal	-3	no	12.861	5.654	EPSD	COSMIC	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	P46013	MKI67	O14757	CHEK1	T1577	S1571N	1571	Missense	distal	-6	no	11.310	11.351	EPSD	COSMIC	5.604	Up-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	P46013	MKI67	O14757	CHEK1	T1577	R1574Q	1574	Missense	distal	-3	no	11.310	4.103	EPSD	COSMIC	5.604	Loss
CAMK_CAMKL_CHK1_CHEK1_ST	P46013	MKI67	O14757	CHEK1	T1577	L1575P	1575	Missense	proximal	-2	no	11.310	11.489	EPSD	COSMIC	5.604	Up-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	P46013	MKI67	O14757	CHEK1	T1577	K1572M	1572	Missense	distal	-5	no	11.310	8.738	EPSD	COSMIC	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	P46013	MKI67	O14757	CHEK1	T1601	L1594F	1594	Missense	distal	-7	no	7.610	6.762	EPSD	COSMIC;GDSC;CCLE	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	P46013	MKI67	O14757	CHEK1	T1601	R1598L	1598	Missense	distal	-3	no	7.610	-10.937	EPSD	COSMIC	5.604	Loss
CAMK_CAMKL_CHK1_CHEK1_ST	P46013	MKI67	O14757	CHEK1	T1601	E1603D	1603	Missense	proximal	2	no	7.610	7.527	EPSD	COSMIC	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	P46013	MKI67	O14757	CHEK1	T1635	K1639T	1639	Missense	distal	4	no	7.087	7.146	EPSD	COSMIC	5.604	Up-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	P46013	MKI67	O14757	CHEK1	T1635	V1642M	1642	Missense	distal	7	no	7.087	6.943	EPSD	COSMIC	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	P46013	MKI67	O14757	CHEK1	T1635	V1640G	1640	Missense	distal	5	no	7.087	6.981	EPSD	COSMIC	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	P46013	MKI67	O14757	CHEK1	T1764	F1768L	1768	Missense	distal	4	no	9.501	9.440	PhosphoSitePlus	COSMIC	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	P46013	MKI67	O14757	CHEK1	T1764	A1770V	1770	Missense	distal	6	no	9.501	9.389	PhosphoSitePlus	COSMIC	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	P46013	MKI67	O14757	CHEK1	T1943	K1947E	1947	Missense	distal	4	no	9.129	9.135	EPSD	COSMIC	5.604	Up-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	P46013	MKI67	O14757	CHEK1	T1943	R1940W	1940	Missense	distal	-3	no	9.129	-24.474	EPSD	COSMIC	5.604	Loss
CAMK_CAMKL_CHK1_CHEK1_ST	P46013	MKI67	O14757	CHEK1	T1943	A1948T	1948	Missense	distal	5	no	9.129	8.888	EPSD	COSMIC	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	P46013	MKI67	O14757	CHEK1	T1943	K1949R	1949	Missense	distal	6	no	9.129	9.217	EPSD	COSMIC	5.604	Up-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	P46013	MKI67	O14757	CHEK1	T1943	S1937N	1937	Missense	distal	-6	no	9.129	9.170	EPSD	COSMIC;GDSC	5.604	Up-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	P46013	MKI67	O14757	CHEK1	T1943	A1950T	1950	Missense	distal	7	no	9.129	9.012	EPSD	COSMIC	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	P46013	MKI67	O14757	CHEK1	T2143	L2140R	2140	Missense	distal	-3	no	-8.186	10.361	EPSD	COSMIC;GDSC;CCLE	5.604	Gain
CAMK_CAMKL_CHK1_CHEK1_ST	P46013	MKI67	O14757	CHEK1	S2173	A2171V	2171	Missense	proximal	-2	no	5.584	5.660	EPSD	COSMIC	5.604	Gain
CAMK_CAMKL_CHK1_CHEK1_ST	P46013	MKI67	O14757	CHEK1	S2252	E2249K	2249	Missense	distal	-3	no	3.791	7.054	EPSD	COSMIC	5.604	Gain
CAMK_CAMKL_CHK1_CHEK1_ST	P46013	MKI67	O14757	CHEK1	S2261	M2266T	2266	Missense	distal	5	no	13.599	13.489	EPSD	COSMIC	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	P46013	MKI67	O14757	CHEK1	S2261	V2262A	2262	Missense	proximal	1	no	13.599	13.624	EPSD	COSMIC	5.604	Up-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	P46013	MKI67	O14757	CHEK1	S2261	T2268K	2268	Missense	distal	7	no	13.599	13.834	EPSD	COSMIC	5.604	Up-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	P46013	MKI67	O14757	CHEK1	T2333	T2337N	2337	Missense	distal	4	no	6.417	6.425	EPSD	COSMIC	5.604	Up-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	P46013	MKI67	O14757	CHEK1	T2333	P2331T	2331	Missense	proximal	-2	no	6.417	6.387	EPSD	COSMIC	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	P46013	MKI67	O14757	CHEK1	T2333	D2334H	2334	Missense	proximal	1	no	6.417	6.272	EPSD	COSMIC	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	P46013	MKI67	O14757	CHEK1	T2333	G2327D	2327	Missense	distal	-6	no	6.417	6.207	EPSD	COSMIC	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	P46013	MKI67	O14757	CHEK1	S2382	T2389R	2389	Missense	distal	7	no	9.988	10.147	EPSD	COSMIC	5.604	Up-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	P46013	MKI67	O14757	CHEK1	S2382	D2388H	2388	Missense	distal	6	no	9.988	10.547	EPSD	COSMIC	5.604	Up-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	P46013	MKI67	O14757	CHEK1	S2382	L2376I	2376	Missense	distal	-6	no	9.988	9.962	EPSD	COSMIC;GDSC;CCLE	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	P46013	MKI67	O14757	CHEK1	T2516	T2513R	2513	Missense	distal	-3	no	-11.563	9.006	EPSD	COSMIC	5.604	Gain
CAMK_CAMKL_CHK1_CHEK1_ST	P46013	MKI67	O14757	CHEK1	T2577	D2579V	2579	Missense	proximal	2	no	6.245	5.672	EPSD	COSMIC	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	P46013	MKI67	O14757	CHEK1	S2920	P2914L	2914	Missense	distal	-6	no	5.683	5.610	EPSD	COSMIC	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	P46013	MKI67	O14757	CHEK1	S2920	A2919T	2919	Missense	proximal	-1	no	5.683	5.554	EPSD	COSMIC	5.604	Loss
CAMK_CAMKL_CHK1_CHEK1_ST	P46013	MKI67	O14757	CHEK1	S2920	S2920N	2920	Missense	central	0	yes	5.683	0.000	EPSD	COSMIC	5.604	Loss
CAMK_CAMKL_CHK1_CHEK1_ST	P46013	MKI67	O14757	CHEK1	S3041	A3037T	3037	Missense	distal	-4	no	11.028	10.597	EPSD	COSMIC	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	P46013	MKI67	O14757	CHEK1	S3041	V3045M	3045	Missense	distal	4	no	11.028	11.027	EPSD	COSMIC	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	P46013	MKI67	O14757	CHEK1	S3249	T3247A	3247	Missense	proximal	-2	no	8.179	8.039	EPSD	COSMIC	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	P46013	MKI67	O14757	CHEK1	S3249	D3252N	3252	Missense	distal	3	no	8.179	7.462	EPSD	COSMIC	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q14186	TFDP1	O14757	CHEK1	S120	G115D	115	Missense	distal	-5	no	9.814	8.992	EPSD	COSMIC	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q14186	TFDP1	O14757	CHEK1	S120	G113S	113	Missense	distal	-7	no	9.814	10.035	EPSD	COSMIC	5.604	Up-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q14186	TFDP1	O14757	CHEK1	T132	G131R	131	Missense	proximal	-1	no	6.695	6.678	EPSD	COSMIC	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q14186	TFDP1	O14757	CHEK1	T133	G131R	131	Missense	proximal	-2	no	7.856	7.822	EPSD	COSMIC	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q14186	TFDP1	O14757	CHEK1	S134	G131R	131	Missense	distal	-3	no	4.726	12.500	EPSD	COSMIC	5.604	Gain
CAMK_CAMKL_CHK1_CHEK1_ST	Q14186	TFDP1	O14757	CHEK1	S147	I153T	153	Missense	distal	6	no	8.124	8.392	EPSD	COSMIC	5.604	Up-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q14186	TFDP1	O14757	CHEK1	S147	A144V	144	Missense	distal	-3	no	8.124	6.373	EPSD	COSMIC	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q14186	TFDP1	O14757	CHEK1	S147	D150N	150	Missense	distal	3	no	8.124	7.408	EPSD	COSMIC;GDSC;CCLE	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q14186	TFDP1	O14757	CHEK1	S315	G312R	312	Missense	distal	-3	no	1.282	9.056	EPSD	COSMIC	5.604	Gain
CAMK_CAMKL_CHK1_CHEK1_ST	Q14186	TFDP1	O14757	CHEK1	T388	V393I	393	Missense	distal	5	no	5.810	5.752	EPSD	COSMIC	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q14186	TFDP1	O14757	CHEK1	T388	E395D	395	Missense	distal	7	no	5.810	5.868	EPSD	COSMIC	5.604	Up-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q9UJM3	ERRFI1	O14757	CHEK1	S302	E304V	304	Missense	proximal	2	no	10.251	9.596	PhosphoSitePlus;EPSD	COSMIC	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q9UJM3	ERRFI1	O14757	CHEK1	S334	R331C	331	Missense	distal	-3	no	8.988	0.896	EPSD	COSMIC	5.604	Loss
CAMK_CAMKL_CHK1_CHEK1_ST	Q9UJM3	ERRFI1	O14757	CHEK1	S334	P339L	339	Missense	distal	5	no	8.988	8.826	EPSD	COSMIC	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q9UJM3	ERRFI1	O14757	CHEK1	S334	R331H	331	Missense	distal	-3	no	8.988	3.178	EPSD	COSMIC	5.604	Loss
CAMK_CAMKL_CHK1_CHEK1_ST	Q9UJM3	ERRFI1	O14757	CHEK1	S334	L338F	338	Missense	distal	4	no	8.988	9.049	EPSD	COSMIC	5.604	Up-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q9BXW9	FANCD2	O14757	CHEK1	S8	E14D	14	Missense	distal	6	no	8.107	8.193	EPSD	COSMIC	5.604	Up-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q9BXW9	FANCD2	O14757	CHEK1	S331	A329T	329	Missense	proximal	-2	no	10.926	11.065	PhosphoSitePlus	COSMIC	5.604	Up-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q9BXW9	FANCD2	O14757	CHEK1	S717	P714L	714	Missense	distal	-3	no	5.613	-5.797	EPSD	COSMIC	5.604	Loss
CAMK_CAMKL_CHK1_CHEK1_ST	Q9BXW9	FANCD2	O14757	CHEK1	S717	G713D	713	Missense	distal	-4	no	5.613	5.649	EPSD	COSMIC	5.604	Up-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q9BXW9	FANCD2	O14757	CHEK1	S978	L972I	972	Missense	distal	-6	no	5.665	5.639	EPSD	COSMIC	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q9BXW9	FANCD2	O14757	CHEK1	S978	T981I	981	Missense	distal	3	no	5.665	5.433	EPSD	COSMIC	5.604	Loss
CAMK_CAMKL_CHK1_CHEK1_ST	Q9UKM9	RALY	O14757	CHEK1	T160	P153S	153	Missense	distal	-7	no	7.506	8.176	PhosphoSitePlus	COSMIC	5.604	Up-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q9UKM9	RALY	O14757	CHEK1	T160	R156W	156	Missense	distal	-4	no	7.506	6.744	PhosphoSitePlus	COSMIC;GDSC	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q9UKM9	RALY	O14757	CHEK1	T160	N161T	161	Missense	proximal	1	no	7.506	7.516	PhosphoSitePlus	COSMIC	5.604	Up-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q9UKM9	RALY	O14757	CHEK1	S184	L187M	187	Missense	distal	3	no	6.004	6.351	EPSD	COSMIC	5.604	Up-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q12888	TP53BP1	O14757	CHEK1	S232	P227L	227	Missense	distal	-5	no	2.520	7.227	EPSD	COSMIC	5.604	Gain
CAMK_CAMKL_CHK1_CHEK1_ST	Q12888	TP53BP1	O14757	CHEK1	S233	S232F	232	Missense	proximal	-1	no	5.475	5.749	EPSD	COSMIC	5.604	Gain
CAMK_CAMKL_CHK1_CHEK1_ST	Q12888	TP53BP1	O14757	CHEK1	T804	E811G	811	Missense	distal	7	no	6.551	6.316	EPSD	COSMIC	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q12888	TP53BP1	O14757	CHEK1	T902	S899R	899	Missense	distal	-3	no	-3.836	5.860	EPSD	COSMIC	5.604	Gain
CAMK_CAMKL_CHK1_CHEK1_ST	Q12888	TP53BP1	O14757	CHEK1	T1012	N1006Y	1006	Missense	distal	-6	no	6.883	7.003	EPSD	COSMIC	5.604	Up-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q12888	TP53BP1	O14757	CHEK1	S1034	S1028I	1028	Missense	distal	-6	no	6.117	6.116	EPSD	COSMIC	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q12888	TP53BP1	O14757	CHEK1	S1034	A1027G	1027	Missense	distal	-7	no	6.117	5.446	EPSD	COSMIC	5.604	Loss
CAMK_CAMKL_CHK1_CHEK1_ST	Q12888	TP53BP1	O14757	CHEK1	S1067	S1068F	1068	Missense	proximal	1	no	6.563	6.558	EPSD	COSMIC	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q12888	TP53BP1	O14757	CHEK1	S1067	F1065I	1065	Missense	proximal	-2	no	6.563	6.401	EPSD	COSMIC	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q12888	TP53BP1	O14757	CHEK1	S1094	P1089L	1089	Missense	distal	-5	no	2.502	7.209	EPSD	COSMIC	5.604	Gain
CAMK_CAMKL_CHK1_CHEK1_ST	Q12888	TP53BP1	O14757	CHEK1	S1208	G1203C	1203	Missense	distal	-5	no	7.549	7.036	EPSD	COSMIC	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q12888	TP53BP1	O14757	CHEK1	S1208	E1204V	1204	Missense	distal	-4	no	7.549	7.338	EPSD	COSMIC	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q12888	TP53BP1	O14757	CHEK1	T1270	E1271Q	1271	Missense	proximal	1	no	8.486	8.420	EPSD	COSMIC	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q12888	TP53BP1	O14757	CHEK1	T1270	P1276L	1276	Missense	distal	6	no	8.486	8.276	EPSD	COSMIC	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q12888	TP53BP1	O14757	CHEK1	T1270	E1266Q	1266	Missense	distal	-4	no	8.486	8.443	EPSD	COSMIC	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q12888	TP53BP1	O14757	CHEK1	T1270	E1272K	1272	Missense	proximal	2	no	8.486	8.528	EPSD	COSMIC	5.604	Up-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q12888	TP53BP1	O14757	CHEK1	S1317	R1314H	1314	Missense	distal	-3	no	11.275	5.465	EPSD	COSMIC	5.604	Loss
CAMK_CAMKL_CHK1_CHEK1_ST	Q12888	TP53BP1	O14757	CHEK1	S1430	S1435F	1435	Missense	distal	5	no	6.504	6.179	EPSD	COSMIC	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q12888	TP53BP1	O14757	CHEK1	S1462	R1458H	1458	Missense	distal	-4	no	11.811	11.614	EPSD	COSMIC	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q12888	TP53BP1	O14757	CHEK1	S1631	S1635P	1635	Missense	distal	4	no	8.527	8.667	EPSD	COSMIC	5.604	Up-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q12888	TP53BP1	O14757	CHEK1	S1631	G1625R	1625	Missense	distal	-6	no	8.527	8.409	EPSD	COSMIC	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q12888	TP53BP1	O14757	CHEK1	S1631	S1635F	1635	Missense	distal	4	no	8.527	8.625	EPSD	COSMIC	5.604	Up-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q12888	TP53BP1	O14757	CHEK1	T1672	E1676Q	1676	Missense	distal	4	no	7.063	7.154	EPSD	COSMIC	5.604	Up-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q12888	TP53BP1	O14757	CHEK1	T1672	P1679S	1679	Missense	distal	7	no	7.063	7.007	EPSD	COSMIC	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q12888	TP53BP1	O14757	CHEK1	S1853	Y1846C	1846	Missense	distal	-7	no	5.803	6.474	EPSD	COSMIC	5.604	Up-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q12888	TP53BP1	O14757	CHEK1	S1853	R1858I	1858	Missense	distal	5	no	5.803	5.763	EPSD	COSMIC;CCLE	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q14966	ZNF638	O14757	CHEK1	S36	R41K	41	Missense	distal	5	no	9.476	9.600	EPSD	COSMIC	5.604	Up-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q14966	ZNF638	O14757	CHEK1	S193	P190R	190	Missense	distal	-3	no	2.562	9.698	EPSD	COSMIC;GDSC;CCLE	5.604	Gain
CAMK_CAMKL_CHK1_CHEK1_ST	Q14966	ZNF638	O14757	CHEK1	S488	R487C	487	Missense	proximal	-1	no	10.760	10.795	EPSD	COSMIC;GDSC	5.604	Up-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q14966	ZNF638	O14757	CHEK1	S488	S490F	490	Missense	proximal	2	no	10.760	10.616	EPSD	COSMIC	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q14966	ZNF638	O14757	CHEK1	S488	R486T	486	Missense	proximal	-2	no	10.760	10.915	EPSD	COSMIC;GDSC;CCLE	5.604	Up-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q14966	ZNF638	O14757	CHEK1	S490	R487C	487	Missense	distal	-3	no	8.142	0.051	EPSD	COSMIC;GDSC	5.604	Loss
CAMK_CAMKL_CHK1_CHEK1_ST	Q14966	ZNF638	O14757	CHEK1	S490	S490F	490	Missense	central	0	yes	8.142	0.000	EPSD	COSMIC	5.604	Loss
CAMK_CAMKL_CHK1_CHEK1_ST	Q14966	ZNF638	O14757	CHEK1	S490	R486T	486	Missense	distal	-4	no	8.142	7.783	EPSD	COSMIC;GDSC;CCLE	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q14966	ZNF638	O14757	CHEK1	S501	S508T	508	Missense	distal	7	no	9.081	9.014	EPSD	COSMIC	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q14966	ZNF638	O14757	CHEK1	S510	S508T	508	Missense	proximal	-2	no	9.474	9.728	EPSD	COSMIC	5.604	Up-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q14966	ZNF638	O14757	CHEK1	S520	P518L	518	Missense	proximal	-2	no	6.328	6.149	EPSD	COSMIC;CCLE	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q14966	ZNF638	O14757	CHEK1	S522	P518L	518	Missense	distal	-4	no	7.756	7.572	EPSD	COSMIC;CCLE	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q14966	ZNF638	O14757	CHEK1	S537	R534T	534	Missense	distal	-3	no	7.789	-12.780	EPSD	COSMIC	5.604	Loss
CAMK_CAMKL_CHK1_CHEK1_ST	Q14966	ZNF638	O14757	CHEK1	S537	R540C	540	Missense	distal	3	no	7.789	6.842	EPSD	COSMIC	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q14966	ZNF638	O14757	CHEK1	S539	R534T	534	Missense	distal	-5	no	9.882	10.803	EPSD	COSMIC	5.604	Up-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q14966	ZNF638	O14757	CHEK1	S539	R540C	540	Missense	proximal	1	no	9.882	9.872	EPSD	COSMIC	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q14966	ZNF638	O14757	CHEK1	S541	R534T	534	Missense	distal	-7	no	7.529	6.922	EPSD	COSMIC	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q14966	ZNF638	O14757	CHEK1	S541	R540C	540	Missense	proximal	-1	no	7.529	7.564	EPSD	COSMIC	5.604	Up-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q14966	ZNF638	O14757	CHEK1	S560	M564L	564	Missense	distal	4	no	8.999	8.925	EPSD	COSMIC	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q14966	ZNF638	O14757	CHEK1	S560	R557L	557	Missense	distal	-3	no	8.999	-9.548	EPSD	COSMIC	5.604	Loss
CAMK_CAMKL_CHK1_CHEK1_ST	Q14966	ZNF638	O14757	CHEK1	S560	E562K	562	Missense	proximal	2	no	8.999	9.040	EPSD	COSMIC	5.604	Up-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q14966	ZNF638	O14757	CHEK1	S605	A600V	600	Missense	distal	-5	no	5.251	7.691	EPSD	COSMIC	5.604	Gain
CAMK_CAMKL_CHK1_CHEK1_ST	Q14966	ZNF638	O14757	CHEK1	S641	L644R	644	Missense	distal	3	no	6.761	7.193	EPSD	COSMIC	5.604	Up-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q14966	ZNF638	O14757	CHEK1	S661	R667W	667	Missense	distal	6	no	5.901	6.367	EPSD	COSMIC;GDSC;CCLE	5.604	Up-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q14966	ZNF638	O14757	CHEK1	S661	Q654R	654	Missense	distal	-7	no	5.901	5.643	EPSD	COSMIC;GDSC;CCLE	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q14966	ZNF638	O14757	CHEK1	S671	Q670L	670	Missense	proximal	-1	no	6.735	6.819	EPSD	COSMIC	5.604	Up-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q14966	ZNF638	O14757	CHEK1	S671	R667W	667	Missense	distal	-4	no	6.735	5.973	EPSD	COSMIC;GDSC;CCLE	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q14966	ZNF638	O14757	CHEK1	S801	Q797H	797	Missense	distal	-4	no	6.110	5.752	EPSD	COSMIC	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q14966	ZNF638	O14757	CHEK1	S801	V805M	805	Missense	distal	4	no	6.110	6.109	EPSD	COSMIC	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q14966	ZNF638	O14757	CHEK1	S801	A803S	803	Missense	proximal	2	no	6.110	5.653	EPSD	COSMIC	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q14966	ZNF638	O14757	CHEK1	S801	S808F	808	Missense	distal	7	no	6.110	5.680	EPSD	COSMIC	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q14966	ZNF638	O14757	CHEK1	S801	G796E	796	Missense	distal	-5	no	6.110	4.889	EPSD	COSMIC	5.604	Loss
CAMK_CAMKL_CHK1_CHEK1_ST	Q14966	ZNF638	O14757	CHEK1	S1052	L1048V	1048	Missense	distal	-4	no	5.557	5.805	EPSD	COSMIC	5.604	Gain
CAMK_CAMKL_CHK1_CHEK1_ST	Q14966	ZNF638	O14757	CHEK1	S1245	S1245C	1245	Missense	central	0	yes	6.669	0.000	EPSD	COSMIC	5.604	Loss
CAMK_CAMKL_CHK1_CHEK1_ST	Q14966	ZNF638	O14757	CHEK1	S1245	E1241V	1241	Missense	distal	-4	no	6.669	6.458	EPSD	COSMIC	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q14966	ZNF638	O14757	CHEK1	S1245	E1248Q	1248	Missense	distal	3	no	6.669	6.269	EPSD	COSMIC	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q14966	ZNF638	O14757	CHEK1	S1468	L1463F	1463	Missense	distal	-5	no	9.304	5.741	EPSD	COSMIC	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q14966	ZNF638	O14757	CHEK1	S1468	R1470K	1470	Missense	proximal	2	no	9.304	9.990	EPSD	COSMIC	5.604	Up-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q14966	ZNF638	O14757	CHEK1	S1468	R1470M	1470	Missense	proximal	2	no	9.304	9.473	EPSD	COSMIC	5.604	Up-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q14966	ZNF638	O14757	CHEK1	S1468	I1471V	1471	Missense	distal	3	no	9.304	10.018	EPSD	COSMIC	5.604	Up-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q14966	ZNF638	O14757	CHEK1	S1479	R1484I	1484	Missense	distal	5	no	6.658	6.618	EPSD	COSMIC	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q14966	ZNF638	O14757	CHEK1	T1487	R1484I	1484	Missense	distal	-3	no	9.382	0.624	EPSD	COSMIC	5.604	Loss
CAMK_CAMKL_CHK1_CHEK1_ST	Q14966	ZNF638	O14757	CHEK1	S1823	S1825F	1825	Missense	proximal	2	no	6.539	6.394	EPSD	COSMIC	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q14966	ZNF638	O14757	CHEK1	S1823	V1827L	1827	Missense	distal	4	no	6.539	6.464	EPSD	COSMIC	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q14966	ZNF638	O14757	CHEK1	T1848	P1852L	1852	Missense	distal	4	no	8.423	8.320	EPSD	COSMIC	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q14966	ZNF638	O14757	CHEK1	T1853	P1852L	1852	Missense	proximal	-1	no	5.828	5.642	EPSD	COSMIC	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q99590	SCAF11	O14757	CHEK1	S413	T410R	410	Missense	distal	-3	no	-13.453	7.116	EPSD	COSMIC	5.604	Gain
CAMK_CAMKL_CHK1_CHEK1_ST	Q99590	SCAF11	O14757	CHEK1	S472	S473L	473	Missense	proximal	1	no	6.655	6.646	EPSD	COSMIC	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q99590	SCAF11	O14757	CHEK1	S472	R469T	469	Missense	distal	-3	no	6.655	-13.914	EPSD	COSMIC	5.604	Loss
CAMK_CAMKL_CHK1_CHEK1_ST	Q99590	SCAF11	O14757	CHEK1	T640	H637Y	637	Missense	distal	-3	no	7.041	-4.093	EPSD	COSMIC	5.604	Loss
CAMK_CAMKL_CHK1_CHEK1_ST	Q99590	SCAF11	O14757	CHEK1	T640	I645V	645	Missense	distal	5	no	7.041	7.099	EPSD	COSMIC	5.604	Up-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q99590	SCAF11	O14757	CHEK1	S687	T689S	689	Missense	proximal	2	no	5.215	5.606	EPSD	COSMIC	5.604	Gain
CAMK_CAMKL_CHK1_CHEK1_ST	Q99590	SCAF11	O14757	CHEK1	T689	T695A	695	Missense	distal	6	no	6.485	6.563	EPSD	COSMIC	5.604	Up-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q99590	SCAF11	O14757	CHEK1	T689	E690A	690	Missense	proximal	1	no	6.485	6.403	EPSD	COSMIC	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q99590	SCAF11	O14757	CHEK1	S796	R793I	793	Missense	distal	-3	no	7.134	-1.624	EPSD	COSMIC	5.604	Loss
CAMK_CAMKL_CHK1_CHEK1_ST	Q99590	SCAF11	O14757	CHEK1	S796	P803L	803	Missense	distal	7	no	7.134	7.071	EPSD	COSMIC;GDSC;CCLE	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q99590	SCAF11	O14757	CHEK1	T823	K829R	829	Missense	distal	6	no	9.084	9.172	EPSD	COSMIC	5.604	Up-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q99590	SCAF11	O14757	CHEK1	S832	K829R	829	Missense	distal	-3	no	5.434	9.259	EPSD	COSMIC	5.604	Gain
CAMK_CAMKL_CHK1_CHEK1_ST	Q99590	SCAF11	O14757	CHEK1	S846	R847H	847	Missense	proximal	1	no	7.652	7.587	EPSD	COSMIC	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q99590	SCAF11	O14757	CHEK1	S846	P851L	851	Missense	distal	5	no	7.652	7.490	EPSD	COSMIC	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q99590	SCAF11	O14757	CHEK1	S846	S850F	850	Missense	distal	4	no	7.652	7.750	EPSD	COSMIC	5.604	Up-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q99590	SCAF11	O14757	CHEK1	S846	R847C	847	Missense	proximal	1	no	7.652	7.642	EPSD	COSMIC	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q99590	SCAF11	O14757	CHEK1	S850	R847H	847	Missense	distal	-3	no	9.731	3.921	EPSD	COSMIC	5.604	Loss
CAMK_CAMKL_CHK1_CHEK1_ST	Q99590	SCAF11	O14757	CHEK1	S850	P851L	851	Missense	proximal	1	no	9.731	9.759	EPSD	COSMIC	5.604	Up-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q99590	SCAF11	O14757	CHEK1	S850	S850F	850	Missense	central	0	yes	9.731	0.000	EPSD	COSMIC	5.604	Loss
CAMK_CAMKL_CHK1_CHEK1_ST	Q99590	SCAF11	O14757	CHEK1	S850	R847C	847	Missense	distal	-3	no	9.731	1.639	EPSD	COSMIC	5.604	Loss
CAMK_CAMKL_CHK1_CHEK1_ST	Q99590	SCAF11	O14757	CHEK1	S880	T887A	887	Missense	distal	7	no	8.233	8.349	EPSD	COSMIC	5.604	Up-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q99590	SCAF11	O14757	CHEK1	S902	P896S	896	Missense	distal	-6	no	7.337	7.239	EPSD	COSMIC	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q99590	SCAF11	O14757	CHEK1	S902	S901F	901	Missense	proximal	-1	no	7.337	7.611	EPSD	COSMIC	5.604	Up-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q99590	SCAF11	O14757	CHEK1	S911	E915K	915	Missense	distal	4	no	10.838	10.832	EPSD	COSMIC;GDSC;CCLE	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q99590	SCAF11	O14757	CHEK1	S937	R940M	940	Missense	distal	3	no	8.093	8.009	EPSD	COSMIC	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q99590	SCAF11	O14757	CHEK1	S937	S937C	937	Missense	central	0	yes	8.093	0.000	EPSD	COSMIC	5.604	Loss
CAMK_CAMKL_CHK1_CHEK1_ST	Q99590	SCAF11	O14757	CHEK1	S937	W932L	932	Missense	distal	-5	no	8.093	11.929	EPSD	COSMIC	5.604	Up-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q99590	SCAF11	O14757	CHEK1	S939	R940M	940	Missense	proximal	1	no	7.553	7.513	EPSD	COSMIC	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q99590	SCAF11	O14757	CHEK1	S939	S937C	937	Missense	proximal	-2	no	7.553	7.600	EPSD	COSMIC	5.604	Up-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q99590	SCAF11	O14757	CHEK1	S939	W932L	932	Missense	distal	-7	no	7.553	8.474	EPSD	COSMIC	5.604	Up-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q99590	SCAF11	O14757	CHEK1	S943	K948N	948	Missense	distal	5	no	6.778	6.756	EPSD	COSMIC	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q99590	SCAF11	O14757	CHEK1	S943	R940M	940	Missense	distal	-3	no	6.778	1.630	EPSD	COSMIC	5.604	Loss
CAMK_CAMKL_CHK1_CHEK1_ST	Q99590	SCAF11	O14757	CHEK1	S943	S937C	937	Missense	distal	-6	no	6.778	6.814	EPSD	COSMIC	5.604	Up-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q99590	SCAF11	O14757	CHEK1	S951	K948N	948	Missense	distal	-3	no	8.936	2.393	EPSD	COSMIC	5.604	Loss
CAMK_CAMKL_CHK1_CHEK1_ST	Q99590	SCAF11	O14757	CHEK1	S953	K948N	948	Missense	distal	-5	no	8.300	7.406	EPSD	COSMIC	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q99590	SCAF11	O14757	CHEK1	S1030	E1026K	1026	Missense	distal	-4	no	8.788	8.686	EPSD	COSMIC	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q99590	SCAF11	O14757	CHEK1	S1030	R1037S	1037	Missense	distal	7	no	8.788	8.695	EPSD	COSMIC	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q99590	SCAF11	O14757	CHEK1	S1030	T1025A	1025	Missense	distal	-5	no	8.788	4.927	EPSD	COSMIC	5.604	Loss
CAMK_CAMKL_CHK1_CHEK1_ST	Q99590	SCAF11	O14757	CHEK1	S1104	S1110L	1110	Missense	distal	6	no	6.104	6.514	EPSD	COSMIC;GDSC;CCLE	5.604	Up-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q99590	SCAF11	O14757	CHEK1	S1104	L1103F	1103	Missense	proximal	-1	no	6.104	6.118	EPSD	COSMIC	5.604	Up-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q99590	SCAF11	O14757	CHEK1	S1127	S1122F	1122	Missense	distal	-5	no	7.093	6.717	PhosphoSitePlus	COSMIC	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q99590	SCAF11	O14757	CHEK1	S1147	S1144R	1144	Missense	distal	-3	no	-2.201	7.494	EPSD	COSMIC	5.604	Gain
CAMK_CAMKL_CHK1_CHEK1_ST	Q99590	SCAF11	O14757	CHEK1	S1170	S1169R	1169	Missense	proximal	-1	no	8.243	8.404	EPSD	COSMIC	5.604	Up-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q99590	SCAF11	O14757	CHEK1	S1170	R1164Q	1164	Missense	distal	-6	no	8.243	8.325	EPSD	COSMIC	5.604	Up-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q99590	SCAF11	O14757	CHEK1	S1170	S1170L	1170	Missense	central	0	yes	8.243	0.000	EPSD	COSMIC	5.604	Loss
CAMK_CAMKL_CHK1_CHEK1_ST	Q99590	SCAF11	O14757	CHEK1	S1170	M1177I	1177	Missense	distal	7	no	8.243	7.966	EPSD	COSMIC;GDSC;CCLE	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q9UQ35	SRRM2	O14757	CHEK1	S24	G17R	17	Missense	distal	-7	no	11.692	11.653	EPSD	COSMIC	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q9UQ35	SRRM2	O14757	CHEK1	S24	R29H	29	Missense	distal	5	no	11.692	11.708	EPSD	COSMIC	5.604	Up-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q9UQ35	SRRM2	O14757	CHEK1	S24	G28D	28	Missense	distal	4	no	11.692	11.675	EPSD	COSMIC	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q9UQ35	SRRM2	O14757	CHEK1	T111	G113R	113	Missense	proximal	2	no	6.570	6.539	EPSD	COSMIC	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q9UQ35	SRRM2	O14757	CHEK1	S178	P185Q	185	Missense	distal	7	no	10.891	11.083	EPSD	COSMIC	5.604	Up-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q9UQ35	SRRM2	O14757	CHEK1	S178	R175Q	175	Missense	distal	-3	no	10.891	3.684	EPSD	COSMIC	5.604	Loss
CAMK_CAMKL_CHK1_CHEK1_ST	Q9UQ35	SRRM2	O14757	CHEK1	T184	P185Q	185	Missense	proximal	1	no	10.108	10.179	EPSD	COSMIC	5.604	Up-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q9UQ35	SRRM2	O14757	CHEK1	S202	R207H	207	Missense	distal	5	no	6.308	6.324	EPSD	COSMIC	5.604	Up-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q9UQ35	SRRM2	O14757	CHEK1	S202	S202C	202	Missense	central	0	yes	6.308	0.000	EPSD	COSMIC	5.604	Loss
CAMK_CAMKL_CHK1_CHEK1_ST	Q9UQ35	SRRM2	O14757	CHEK1	S202	R198H	198	Missense	distal	-4	no	6.308	6.111	EPSD	COSMIC	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q9UQ35	SRRM2	O14757	CHEK1	S212	R207H	207	Missense	distal	-5	no	6.451	3.986	EPSD	COSMIC	5.604	Loss
CAMK_CAMKL_CHK1_CHEK1_ST	Q9UQ35	SRRM2	O14757	CHEK1	S222	H229Y	229	Missense	distal	7	no	11.709	11.395	EPSD	COSMIC	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q9UQ35	SRRM2	O14757	CHEK1	T233	H229Y	229	Missense	distal	-4	no	8.336	8.048	EPSD	COSMIC	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q9UQ35	SRRM2	O14757	CHEK1	S279	S277T	277	Missense	proximal	-2	no	10.720	10.974	EPSD	COSMIC	5.604	Up-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q9UQ35	SRRM2	O14757	CHEK1	S279	R280Q	280	Missense	proximal	1	no	10.720	10.729	EPSD	COSMIC	5.604	Up-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q9UQ35	SRRM2	O14757	CHEK1	S279	R278Q	278	Missense	proximal	-1	no	10.720	10.736	EPSD	COSMIC	5.604	Up-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q9UQ35	SRRM2	O14757	CHEK1	S281	S277T	277	Missense	distal	-4	no	8.075	8.024	EPSD	COSMIC	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q9UQ35	SRRM2	O14757	CHEK1	S281	R280Q	280	Missense	proximal	-1	no	8.075	8.090	EPSD	COSMIC	5.604	Up-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q9UQ35	SRRM2	O14757	CHEK1	S281	R278Q	278	Missense	distal	-3	no	8.075	0.868	EPSD	COSMIC	5.604	Loss
CAMK_CAMKL_CHK1_CHEK1_ST	Q9UQ35	SRRM2	O14757	CHEK1	S297	A290S	290	Missense	distal	-7	no	8.855	8.405	EPSD	COSMIC	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q9UQ35	SRRM2	O14757	CHEK1	S323	K329R	329	Missense	distal	6	no	9.116	9.204	EPSD	COSMIC	5.604	Up-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q9UQ35	SRRM2	O14757	CHEK1	S323	T326I	326	Missense	distal	3	no	9.116	8.885	EPSD	COSMIC	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q9UQ35	SRRM2	O14757	CHEK1	S323	R320W	320	Missense	distal	-3	no	9.116	-24.487	EPSD	COSMIC	5.604	Loss
CAMK_CAMKL_CHK1_CHEK1_ST	Q9UQ35	SRRM2	O14757	CHEK1	S323	E325Q	325	Missense	proximal	2	no	9.116	9.001	EPSD	COSMIC	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q9UQ35	SRRM2	O14757	CHEK1	T348	S351N	351	Missense	distal	3	no	5.816	6.657	EPSD	COSMIC	5.604	Up-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q9UQ35	SRRM2	O14757	CHEK1	S404	D402G	402	Missense	proximal	-2	no	9.541	9.627	EPSD	COSMIC	5.604	Up-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q9UQ35	SRRM2	O14757	CHEK1	S404	R403C	403	Missense	proximal	-1	no	9.541	9.576	EPSD	COSMIC;GDSC;CCLE	5.604	Up-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q9UQ35	SRRM2	O14757	CHEK1	S404	R403H	403	Missense	proximal	-1	no	9.541	9.667	EPSD	COSMIC;GDSC;CCLE	5.604	Up-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q9UQ35	SRRM2	O14757	CHEK1	S404	P406S	406	Missense	proximal	2	no	9.541	9.618	EPSD	COSMIC	5.604	Up-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q9UQ35	SRRM2	O14757	CHEK1	S404	T400I	400	Missense	distal	-4	no	9.541	9.612	EPSD	COSMIC;GDSC;CCLE	5.604	Up-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q9UQ35	SRRM2	O14757	CHEK1	S486	A490T	490	Missense	distal	4	no	6.013	5.831	EPSD	COSMIC;GDSC	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q9UQ35	SRRM2	O14757	CHEK1	S486	R479C	479	Missense	distal	-7	no	6.013	5.285	EPSD	COSMIC	5.604	Loss
CAMK_CAMKL_CHK1_CHEK1_ST	Q9UQ35	SRRM2	O14757	CHEK1	S486	R479H	479	Missense	distal	-7	no	6.013	5.954	EPSD	COSMIC	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q9UQ35	SRRM2	O14757	CHEK1	S495	A490T	490	Missense	distal	-5	no	6.706	10.567	EPSD	COSMIC;GDSC	5.604	Up-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q9UQ35	SRRM2	O14757	CHEK1	S495	R496W	496	Missense	proximal	1	no	6.706	6.676	EPSD	COSMIC	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q9UQ35	SRRM2	O14757	CHEK1	S497	A490T	490	Missense	distal	-7	no	11.538	10.221	EPSD	COSMIC;GDSC	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q9UQ35	SRRM2	O14757	CHEK1	S497	R496W	496	Missense	proximal	-1	no	11.538	11.655	EPSD	COSMIC	5.604	Up-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q9UQ35	SRRM2	O14757	CHEK1	T499	R496W	496	Missense	distal	-3	no	8.894	-24.709	EPSD	COSMIC	5.604	Loss
CAMK_CAMKL_CHK1_CHEK1_ST	Q9UQ35	SRRM2	O14757	CHEK1	T501	R496W	496	Missense	distal	-5	no	10.444	9.585	EPSD	COSMIC	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q9UQ35	SRRM2	O14757	CHEK1	S506	Q512H	512	Missense	distal	6	no	10.490	10.785	EPSD	COSMIC;GDSC;CCLE	5.604	Up-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q9UQ35	SRRM2	O14757	CHEK1	S510	R514H	514	Missense	distal	4	no	8.007	8.168	EPSD	COSMIC;CCLE	5.604	Up-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q9UQ35	SRRM2	O14757	CHEK1	S510	Q512H	512	Missense	proximal	2	no	8.007	7.497	EPSD	COSMIC;GDSC;CCLE	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q9UQ35	SRRM2	O14757	CHEK1	S518	R514H	514	Missense	distal	-4	no	9.935	9.738	EPSD	COSMIC;CCLE	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q9UQ35	SRRM2	O14757	CHEK1	S518	R524S	524	Missense	distal	6	no	9.935	9.847	EPSD	COSMIC	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q9UQ35	SRRM2	O14757	CHEK1	S518	Q512H	512	Missense	distal	-6	no	9.935	9.963	EPSD	COSMIC;GDSC;CCLE	5.604	Up-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q9UQ35	SRRM2	O14757	CHEK1	S527	R524S	524	Missense	distal	-3	no	10.142	0.446	EPSD	COSMIC	5.604	Loss
CAMK_CAMKL_CHK1_CHEK1_ST	Q9UQ35	SRRM2	O14757	CHEK1	S534	G541C	541	Missense	distal	7	no	10.389	9.978	EPSD	COSMIC	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q9UQ35	SRRM2	O14757	CHEK1	S534	Q538R	538	Missense	distal	4	no	10.389	10.390	EPSD	COSMIC	5.604	Up-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q9UQ35	SRRM2	O14757	CHEK1	S536	G541C	541	Missense	distal	5	no	10.394	10.238	EPSD	COSMIC	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q9UQ35	SRRM2	O14757	CHEK1	S536	Q538R	538	Missense	proximal	2	no	10.394	9.866	EPSD	COSMIC	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q9UQ35	SRRM2	O14757	CHEK1	S543	G541C	541	Missense	proximal	-2	no	5.717	5.632	EPSD	COSMIC	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q9UQ35	SRRM2	O14757	CHEK1	S543	Q538R	538	Missense	distal	-5	no	5.717	6.114	EPSD	COSMIC	5.604	Up-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q9UQ35	SRRM2	O14757	CHEK1	S562	A557T	557	Missense	distal	-5	no	7.793	11.654	EPSD	COSMIC	5.604	Up-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q9UQ35	SRRM2	O14757	CHEK1	S564	A557T	557	Missense	distal	-7	no	10.230	8.914	EPSD	COSMIC	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q9UQ35	SRRM2	O14757	CHEK1	S573	R574C	574	Missense	proximal	1	no	7.570	7.561	EPSD	COSMIC	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q9UQ35	SRRM2	O14757	CHEK1	S573	R572I	572	Missense	proximal	-1	no	7.570	7.527	EPSD	COSMIC	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q9UQ35	SRRM2	O14757	CHEK1	S573	S573Y	573	Missense	central	0	yes	7.570	0.000	EPSD	COSMIC	5.604	Loss
CAMK_CAMKL_CHK1_CHEK1_ST	Q9UQ35	SRRM2	O14757	CHEK1	S573	R574H	574	Missense	proximal	1	no	7.570	7.505	EPSD	COSMIC	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q9UQ35	SRRM2	O14757	CHEK1	S575	R574C	574	Missense	proximal	-1	no	11.312	11.347	EPSD	COSMIC	5.604	Up-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q9UQ35	SRRM2	O14757	CHEK1	S575	R572I	572	Missense	distal	-3	no	11.312	2.554	EPSD	COSMIC	5.604	Loss
CAMK_CAMKL_CHK1_CHEK1_ST	Q9UQ35	SRRM2	O14757	CHEK1	S575	R581W	581	Missense	distal	6	no	11.312	11.778	EPSD	COSMIC;GDSC;CCLE	5.604	Up-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q9UQ35	SRRM2	O14757	CHEK1	S575	S573Y	573	Missense	proximal	-2	no	11.312	11.424	EPSD	COSMIC	5.604	Up-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q9UQ35	SRRM2	O14757	CHEK1	S575	R574H	574	Missense	proximal	-1	no	11.312	11.437	EPSD	COSMIC	5.604	Up-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q9UQ35	SRRM2	O14757	CHEK1	S575	G582S	582	Missense	distal	7	no	11.312	11.213	EPSD	COSMIC	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q9UQ35	SRRM2	O14757	CHEK1	T577	R574C	574	Missense	distal	-3	no	10.330	2.238	EPSD	COSMIC	5.604	Loss
CAMK_CAMKL_CHK1_CHEK1_ST	Q9UQ35	SRRM2	O14757	CHEK1	T577	R572I	572	Missense	distal	-5	no	10.330	11.275	EPSD	COSMIC	5.604	Up-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q9UQ35	SRRM2	O14757	CHEK1	T577	R581W	581	Missense	distal	4	no	10.330	10.393	EPSD	COSMIC;GDSC;CCLE	5.604	Up-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q9UQ35	SRRM2	O14757	CHEK1	T577	S573Y	573	Missense	distal	-4	no	10.330	10.153	EPSD	COSMIC	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q9UQ35	SRRM2	O14757	CHEK1	T577	R574H	574	Missense	distal	-3	no	10.330	4.520	EPSD	COSMIC	5.604	Loss
CAMK_CAMKL_CHK1_CHEK1_ST	Q9UQ35	SRRM2	O14757	CHEK1	T577	G582S	582	Missense	distal	5	no	10.330	10.521	EPSD	COSMIC	5.604	Up-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q9UQ35	SRRM2	O14757	CHEK1	S584	R581W	581	Missense	distal	-3	no	7.028	-26.575	EPSD	COSMIC;GDSC;CCLE	5.604	Loss
CAMK_CAMKL_CHK1_CHEK1_ST	Q9UQ35	SRRM2	O14757	CHEK1	S584	G582S	582	Missense	proximal	-2	no	7.028	6.895	EPSD	COSMIC	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q9UQ35	SRRM2	O14757	CHEK1	S586	R581W	581	Missense	distal	-5	no	9.434	8.575	EPSD	COSMIC;GDSC;CCLE	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q9UQ35	SRRM2	O14757	CHEK1	S586	G582S	582	Missense	distal	-4	no	9.434	9.100	EPSD	COSMIC	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q9UQ35	SRRM2	O14757	CHEK1	T588	R581W	581	Missense	distal	-7	no	9.565	8.019	EPSD	COSMIC;GDSC;CCLE	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q9UQ35	SRRM2	O14757	CHEK1	T588	G582S	582	Missense	distal	-6	no	9.565	9.527	EPSD	COSMIC	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q9UQ35	SRRM2	O14757	CHEK1	T588	R595L	595	Missense	distal	7	no	9.565	9.465	EPSD	COSMIC	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q9UQ35	SRRM2	O14757	CHEK1	S594	P599S	599	Missense	distal	5	no	8.725	8.807	EPSD	COSMIC	5.604	Up-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q9UQ35	SRRM2	O14757	CHEK1	S594	R595L	595	Missense	proximal	1	no	8.725	8.690	EPSD	COSMIC	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q9UQ35	SRRM2	O14757	CHEK1	S596	P599S	599	Missense	distal	3	no	9.124	8.794	EPSD	COSMIC	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q9UQ35	SRRM2	O14757	CHEK1	S596	R602H	602	Missense	distal	6	no	9.124	9.412	EPSD	COSMIC	5.604	Up-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q9UQ35	SRRM2	O14757	CHEK1	S596	R595L	595	Missense	proximal	-1	no	9.124	9.223	EPSD	COSMIC	5.604	Up-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q9UQ35	SRRM2	O14757	CHEK1	T598	P599S	599	Missense	proximal	1	no	9.349	9.386	EPSD	COSMIC	5.604	Up-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q9UQ35	SRRM2	O14757	CHEK1	T598	R602H	602	Missense	distal	4	no	9.349	9.511	EPSD	COSMIC	5.604	Up-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q9UQ35	SRRM2	O14757	CHEK1	T598	R605Q	605	Missense	distal	7	no	9.349	9.504	EPSD	COSMIC	5.604	Up-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q9UQ35	SRRM2	O14757	CHEK1	T598	R595L	595	Missense	distal	-3	no	9.349	-9.197	EPSD	COSMIC	5.604	Loss
CAMK_CAMKL_CHK1_CHEK1_ST	Q9UQ35	SRRM2	O14757	CHEK1	T600	P599S	599	Missense	proximal	-1	no	10.532	10.085	EPSD	COSMIC	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q9UQ35	SRRM2	O14757	CHEK1	T600	R602H	602	Missense	proximal	2	no	10.532	10.551	EPSD	COSMIC	5.604	Up-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q9UQ35	SRRM2	O14757	CHEK1	T600	R605Q	605	Missense	distal	5	no	10.532	10.608	EPSD	COSMIC	5.604	Up-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q9UQ35	SRRM2	O14757	CHEK1	T600	R595L	595	Missense	distal	-5	no	10.532	13.509	EPSD	COSMIC	5.604	Up-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q9UQ35	SRRM2	O14757	CHEK1	S604	P599S	599	Missense	distal	-5	no	9.233	10.752	EPSD	COSMIC	5.604	Up-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q9UQ35	SRRM2	O14757	CHEK1	S604	R602H	602	Missense	proximal	-2	no	9.233	9.297	EPSD	COSMIC	5.604	Up-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q9UQ35	SRRM2	O14757	CHEK1	S604	R605Q	605	Missense	proximal	1	no	9.233	9.241	EPSD	COSMIC	5.604	Up-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q9UQ35	SRRM2	O14757	CHEK1	S604	R611L	611	Missense	distal	7	no	9.233	9.132	EPSD	COSMIC	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q9UQ35	SRRM2	O14757	CHEK1	S606	G613S	613	Missense	distal	7	no	11.265	11.167	EPSD	COSMIC	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q9UQ35	SRRM2	O14757	CHEK1	S606	P599S	599	Missense	distal	-7	no	11.265	11.935	EPSD	COSMIC	5.604	Up-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q9UQ35	SRRM2	O14757	CHEK1	S606	R602H	602	Missense	distal	-4	no	11.265	11.068	EPSD	COSMIC	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q9UQ35	SRRM2	O14757	CHEK1	S606	R605Q	605	Missense	proximal	-1	no	11.265	11.281	EPSD	COSMIC	5.604	Up-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q9UQ35	SRRM2	O14757	CHEK1	S606	R611L	611	Missense	distal	5	no	11.265	11.125	EPSD	COSMIC	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q9UQ35	SRRM2	O14757	CHEK1	T608	G613S	613	Missense	distal	5	no	8.834	9.025	EPSD	COSMIC	5.604	Up-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q9UQ35	SRRM2	O14757	CHEK1	T608	R602H	602	Missense	distal	-6	no	8.834	8.944	EPSD	COSMIC	5.604	Up-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q9UQ35	SRRM2	O14757	CHEK1	T608	R605Q	605	Missense	distal	-3	no	8.834	1.627	EPSD	COSMIC	5.604	Loss
CAMK_CAMKL_CHK1_CHEK1_ST	Q9UQ35	SRRM2	O14757	CHEK1	T608	R611L	611	Missense	distal	3	no	8.834	8.402	EPSD	COSMIC	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q9UQ35	SRRM2	O14757	CHEK1	S615	G613S	613	Missense	proximal	-2	no	8.413	8.280	EPSD	COSMIC	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q9UQ35	SRRM2	O14757	CHEK1	S615	R611L	611	Missense	distal	-4	no	8.413	8.157	EPSD	COSMIC	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q9UQ35	SRRM2	O14757	CHEK1	S615	R622K	622	Missense	distal	7	no	8.413	8.488	EPSD	COSMIC	5.604	Up-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q9UQ35	SRRM2	O14757	CHEK1	S615	R616W	616	Missense	proximal	1	no	8.413	8.383	EPSD	COSMIC;CCLE	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q9UQ35	SRRM2	O14757	CHEK1	S617	G613S	613	Missense	distal	-4	no	10.600	10.266	EPSD	COSMIC	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q9UQ35	SRRM2	O14757	CHEK1	S617	R611L	611	Missense	distal	-6	no	10.600	10.705	EPSD	COSMIC	5.604	Up-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q9UQ35	SRRM2	O14757	CHEK1	S617	R622K	622	Missense	distal	5	no	10.600	10.724	EPSD	COSMIC	5.604	Up-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q9UQ35	SRRM2	O14757	CHEK1	S617	R616W	616	Missense	proximal	-1	no	10.600	10.718	EPSD	COSMIC;CCLE	5.604	Up-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q9UQ35	SRRM2	O14757	CHEK1	T619	G613S	613	Missense	distal	-6	no	9.168	9.131	EPSD	COSMIC	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q9UQ35	SRRM2	O14757	CHEK1	T619	R622K	622	Missense	distal	3	no	9.168	9.815	EPSD	COSMIC	5.604	Up-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q9UQ35	SRRM2	O14757	CHEK1	T619	R616W	616	Missense	distal	-3	no	9.168	-24.435	EPSD	COSMIC;CCLE	5.604	Loss
CAMK_CAMKL_CHK1_CHEK1_ST	Q9UQ35	SRRM2	O14757	CHEK1	S625	R622K	622	Missense	distal	-3	no	10.749	6.924	EPSD	COSMIC	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q9UQ35	SRRM2	O14757	CHEK1	T627	R622K	622	Missense	distal	-5	no	8.793	9.969	EPSD	COSMIC	5.604	Up-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q9UQ35	SRRM2	O14757	CHEK1	S629	R636H	636	Missense	distal	7	no	9.936	9.643	EPSD	COSMIC	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q9UQ35	SRRM2	O14757	CHEK1	S629	R622K	622	Missense	distal	-7	no	9.936	11.116	EPSD	COSMIC	5.604	Up-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q9UQ35	SRRM2	O14757	CHEK1	S635	R636H	636	Missense	proximal	1	no	9.654	9.588	EPSD	COSMIC	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q9UQ35	SRRM2	O14757	CHEK1	S637	R636H	636	Missense	proximal	-1	no	11.078	11.203	EPSD	COSMIC	5.604	Up-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q9UQ35	SRRM2	O14757	CHEK1	S639	R636H	636	Missense	distal	-3	no	10.214	4.405	EPSD	COSMIC	5.604	Loss
CAMK_CAMKL_CHK1_CHEK1_ST	Q9UQ35	SRRM2	O14757	CHEK1	S639	R646S	646	Missense	distal	7	no	10.214	10.121	EPSD	COSMIC	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q9UQ35	SRRM2	O14757	CHEK1	S644	S647A	647	Missense	distal	3	no	6.073	6.168	EPSD	COSMIC	5.604	Up-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q9UQ35	SRRM2	O14757	CHEK1	S644	R646S	646	Missense	proximal	2	no	6.073	6.169	EPSD	COSMIC	5.604	Up-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q9UQ35	SRRM2	O14757	CHEK1	S649	P652A	652	Missense	distal	3	no	8.534	8.299	EPSD	COSMIC	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q9UQ35	SRRM2	O14757	CHEK1	S649	R655C	655	Missense	distal	6	no	8.534	8.828	EPSD	COSMIC;GDSC;CCLE	5.604	Up-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q9UQ35	SRRM2	O14757	CHEK1	S649	S647A	647	Missense	proximal	-2	no	8.534	8.649	EPSD	COSMIC	5.604	Up-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q9UQ35	SRRM2	O14757	CHEK1	S649	R646S	646	Missense	distal	-3	no	8.534	-1.162	EPSD	COSMIC	5.604	Loss
CAMK_CAMKL_CHK1_CHEK1_ST	Q9UQ35	SRRM2	O14757	CHEK1	S649	R655H	655	Missense	distal	6	no	8.534	8.822	EPSD	COSMIC	5.604	Up-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q9UQ35	SRRM2	O14757	CHEK1	T651	P652A	652	Missense	proximal	1	no	9.375	9.429	EPSD	COSMIC	5.604	Up-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q9UQ35	SRRM2	O14757	CHEK1	T651	R655C	655	Missense	distal	4	no	9.375	9.478	EPSD	COSMIC;GDSC;CCLE	5.604	Up-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q9UQ35	SRRM2	O14757	CHEK1	T651	S647A	647	Missense	distal	-4	no	9.375	9.754	EPSD	COSMIC	5.604	Up-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q9UQ35	SRRM2	O14757	CHEK1	T651	R657H	657	Missense	distal	6	no	9.375	9.663	EPSD	COSMIC	5.604	Up-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q9UQ35	SRRM2	O14757	CHEK1	T651	R646S	646	Missense	distal	-5	no	9.375	9.163	EPSD	COSMIC	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q9UQ35	SRRM2	O14757	CHEK1	T651	R655H	655	Missense	distal	4	no	9.375	9.536	EPSD	COSMIC	5.604	Up-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q9UQ35	SRRM2	O14757	CHEK1	T651	R657L	657	Missense	distal	6	no	9.375	9.696	EPSD	COSMIC	5.604	Up-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q9UQ35	SRRM2	O14757	CHEK1	S660	R655C	655	Missense	distal	-5	no	11.050	10.371	EPSD	COSMIC;GDSC;CCLE	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q9UQ35	SRRM2	O14757	CHEK1	S660	R666H	666	Missense	distal	6	no	11.050	11.338	EPSD	COSMIC	5.604	Up-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q9UQ35	SRRM2	O14757	CHEK1	S660	A664T	664	Missense	distal	4	no	11.050	10.868	EPSD	COSMIC	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q9UQ35	SRRM2	O14757	CHEK1	S660	R657H	657	Missense	distal	-3	no	11.050	5.240	EPSD	COSMIC	5.604	Loss
CAMK_CAMKL_CHK1_CHEK1_ST	Q9UQ35	SRRM2	O14757	CHEK1	S660	R655H	655	Missense	distal	-5	no	11.050	8.585	EPSD	COSMIC	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q9UQ35	SRRM2	O14757	CHEK1	S660	R657L	657	Missense	distal	-3	no	11.050	-7.497	EPSD	COSMIC	5.604	Loss
CAMK_CAMKL_CHK1_CHEK1_ST	Q9UQ35	SRRM2	O14757	CHEK1	T662	R655C	655	Missense	distal	-7	no	8.408	7.680	EPSD	COSMIC;GDSC;CCLE	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q9UQ35	SRRM2	O14757	CHEK1	T662	R666H	666	Missense	distal	4	no	8.408	8.569	EPSD	COSMIC	5.604	Up-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q9UQ35	SRRM2	O14757	CHEK1	T662	A664T	664	Missense	proximal	2	no	8.408	7.560	EPSD	COSMIC	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q9UQ35	SRRM2	O14757	CHEK1	T662	R657H	657	Missense	distal	-5	no	8.408	5.943	EPSD	COSMIC	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q9UQ35	SRRM2	O14757	CHEK1	T662	R655H	655	Missense	distal	-7	no	8.408	8.349	EPSD	COSMIC	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q9UQ35	SRRM2	O14757	CHEK1	T662	R657L	657	Missense	distal	-5	no	8.408	11.385	EPSD	COSMIC	5.604	Up-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q9UQ35	SRRM2	O14757	CHEK1	S669	R666H	666	Missense	distal	-3	no	8.147	2.338	EPSD	COSMIC	5.604	Loss
CAMK_CAMKL_CHK1_CHEK1_ST	Q9UQ35	SRRM2	O14757	CHEK1	S669	A664T	664	Missense	distal	-5	no	8.147	12.008	EPSD	COSMIC	5.604	Up-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q9UQ35	SRRM2	O14757	CHEK1	S671	R666H	666	Missense	distal	-5	no	10.095	7.630	EPSD	COSMIC	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q9UQ35	SRRM2	O14757	CHEK1	S671	A664T	664	Missense	distal	-7	no	10.095	8.778	EPSD	COSMIC	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q9UQ35	SRRM2	O14757	CHEK1	T673	R666H	666	Missense	distal	-7	no	9.960	9.901	EPSD	COSMIC	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q9UQ35	SRRM2	O14757	CHEK1	S683	T685A	685	Missense	proximal	2	no	9.973	10.821	EPSD	COSMIC	5.604	Up-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q9UQ35	SRRM2	O14757	CHEK1	T685	T685A	685	Missense	central	0	yes	9.371	0.000	EPSD	COSMIC	5.604	Loss
CAMK_CAMKL_CHK1_CHEK1_ST	Q9UQ35	SRRM2	O14757	CHEK1	S692	T685A	685	Missense	distal	-7	no	5.825	7.142	EPSD	COSMIC	5.604	Up-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q9UQ35	SRRM2	O14757	CHEK1	S692	R695K	695	Missense	distal	3	no	5.825	6.471	EPSD	COSMIC	5.604	Up-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q9UQ35	SRRM2	O14757	CHEK1	T696	R695K	695	Missense	proximal	-1	no	8.455	8.306	EPSD	COSMIC	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q9UQ35	SRRM2	O14757	CHEK1	S702	R695K	695	Missense	distal	-7	no	8.184	9.364	EPSD	COSMIC	5.604	Up-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q9UQ35	SRRM2	O14757	CHEK1	S724	R730Q	730	Missense	distal	6	no	9.792	9.785	EPSD	COSMIC	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q9UQ35	SRRM2	O14757	CHEK1	S724	S726L	726	Missense	proximal	2	no	9.792	9.398	EPSD	COSMIC	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q9UQ35	SRRM2	O14757	CHEK1	S724	S724F	724	Missense	central	0	yes	9.792	0.000	EPSD	COSMIC	5.604	Loss
CAMK_CAMKL_CHK1_CHEK1_ST	Q9UQ35	SRRM2	O14757	CHEK1	S726	S726L	726	Missense	central	0	yes	9.372	0.000	EPSD	COSMIC	5.604	Loss
CAMK_CAMKL_CHK1_CHEK1_ST	Q9UQ35	SRRM2	O14757	CHEK1	S726	S724F	724	Missense	proximal	-2	no	9.372	9.662	EPSD	COSMIC	5.604	Up-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q9UQ35	SRRM2	O14757	CHEK1	T736	S741G	741	Missense	distal	5	no	6.428	6.237	EPSD	COSMIC	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q9UQ35	SRRM2	O14757	CHEK1	T736	R730Q	730	Missense	distal	-6	no	6.428	6.510	EPSD	COSMIC	5.604	Up-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q9UQ35	SRRM2	O14757	CHEK1	T736	R740K	740	Missense	distal	4	no	6.428	6.330	EPSD	COSMIC	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q9UQ35	SRRM2	O14757	CHEK1	T736	R742K	742	Missense	distal	6	no	6.428	6.340	EPSD	COSMIC	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q9UQ35	SRRM2	O14757	CHEK1	S743	S741G	741	Missense	proximal	-2	no	6.639	6.771	EPSD	COSMIC	5.604	Up-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q9UQ35	SRRM2	O14757	CHEK1	S743	R740K	740	Missense	distal	-3	no	6.639	2.813	EPSD	COSMIC	5.604	Loss
CAMK_CAMKL_CHK1_CHEK1_ST	Q9UQ35	SRRM2	O14757	CHEK1	S743	P747L	747	Missense	distal	4	no	6.639	6.535	EPSD	COSMIC	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q9UQ35	SRRM2	O14757	CHEK1	S743	R742K	742	Missense	proximal	-1	no	6.639	6.490	EPSD	COSMIC	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q9UQ35	SRRM2	O14757	CHEK1	S745	S741G	741	Missense	distal	-4	no	8.179	8.513	EPSD	COSMIC	5.604	Up-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q9UQ35	SRRM2	O14757	CHEK1	S745	R740K	740	Missense	distal	-5	no	8.179	9.354	EPSD	COSMIC	5.604	Up-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q9UQ35	SRRM2	O14757	CHEK1	S745	P747L	747	Missense	proximal	2	no	8.179	7.861	EPSD	COSMIC	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q9UQ35	SRRM2	O14757	CHEK1	S745	R742K	742	Missense	distal	-3	no	8.179	4.353	EPSD	COSMIC	5.604	Loss
CAMK_CAMKL_CHK1_CHEK1_ST	Q9UQ35	SRRM2	O14757	CHEK1	S756	S755F	755	Missense	proximal	-1	no	9.432	9.706	EPSD	COSMIC	5.604	Up-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q9UQ35	SRRM2	O14757	CHEK1	S761	S755F	755	Missense	distal	-6	no	7.275	7.548	EPSD	COSMIC	5.604	Up-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q9UQ35	SRRM2	O14757	CHEK1	S761	S764L	764	Missense	distal	3	no	7.275	6.841	EPSD	COSMIC	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q9UQ35	SRRM2	O14757	CHEK1	S763	S764L	764	Missense	proximal	1	no	9.043	9.034	EPSD	COSMIC	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q9UQ35	SRRM2	O14757	CHEK1	S780	P784L	784	Missense	distal	4	no	11.388	11.285	EPSD	COSMIC	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q9UQ35	SRRM2	O14757	CHEK1	S799	P804A	804	Missense	distal	5	no	5.671	5.772	EPSD	COSMIC	5.604	Up-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q9UQ35	SRRM2	O14757	CHEK1	S799	R796C	796	Missense	distal	-3	no	5.671	-2.420	EPSD	COSMIC	5.604	Loss
CAMK_CAMKL_CHK1_CHEK1_ST	Q9UQ35	SRRM2	O14757	CHEK1	S799	Q803L	803	Missense	distal	4	no	5.671	5.657	EPSD	COSMIC	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q9UQ35	SRRM2	O14757	CHEK1	S808	Q803L	803	Missense	distal	-5	no	2.825	6.198	EPSD	COSMIC	5.604	Gain
CAMK_CAMKL_CHK1_CHEK1_ST	Q9UQ35	SRRM2	O14757	CHEK1	S817	R814C	814	Missense	distal	-3	no	6.577	-1.515	EPSD	COSMIC	5.604	Loss
CAMK_CAMKL_CHK1_CHEK1_ST	Q9UQ35	SRRM2	O14757	CHEK1	S817	R816H	816	Missense	proximal	-1	no	6.577	6.702	EPSD	COSMIC	5.604	Up-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q9UQ35	SRRM2	O14757	CHEK1	S817	R814H	814	Missense	distal	-3	no	6.577	0.767	EPSD	COSMIC;CCLE	5.604	Loss
CAMK_CAMKL_CHK1_CHEK1_ST	Q9UQ35	SRRM2	O14757	CHEK1	S819	R814C	814	Missense	distal	-5	no	7.934	7.256	EPSD	COSMIC	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q9UQ35	SRRM2	O14757	CHEK1	S819	R816H	816	Missense	distal	-3	no	7.934	2.125	EPSD	COSMIC	5.604	Loss
CAMK_CAMKL_CHK1_CHEK1_ST	Q9UQ35	SRRM2	O14757	CHEK1	S819	R814H	814	Missense	distal	-5	no	7.934	5.469	EPSD	COSMIC;CCLE	5.604	Loss
CAMK_CAMKL_CHK1_CHEK1_ST	Q9UQ35	SRRM2	O14757	CHEK1	S831	K828E	828	Missense	distal	-3	no	8.136	4.873	EPSD	COSMIC	5.604	Loss
CAMK_CAMKL_CHK1_CHEK1_ST	Q9UQ35	SRRM2	O14757	CHEK1	S831	R832T	832	Missense	proximal	1	no	8.136	8.118	EPSD	COSMIC	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q9UQ35	SRRM2	O14757	CHEK1	S831	P830S	830	Missense	proximal	-1	no	8.136	7.689	EPSD	COSMIC	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q9UQ35	SRRM2	O14757	CHEK1	S854	T856R	856	Missense	proximal	2	no	5.868	6.164	EPSD	COSMIC	5.604	Up-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q9UQ35	SRRM2	O14757	CHEK1	S887	T885I	885	Missense	proximal	-2	no	9.297	9.171	EPSD	COSMIC	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q9UQ35	SRRM2	O14757	CHEK1	S887	C891Y	891	Missense	distal	4	no	9.297	9.317	EPSD	COSMIC	5.604	Up-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q9UQ35	SRRM2	O14757	CHEK1	S887	S892L	892	Missense	distal	5	no	9.297	9.053	EPSD	COSMIC	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q9UQ35	SRRM2	O14757	CHEK1	S901	S901C	901	Missense	central	0	yes	6.530	0.000	EPSD	COSMIC	5.604	Loss
CAMK_CAMKL_CHK1_CHEK1_ST	Q9UQ35	SRRM2	O14757	CHEK1	S901	R906T	906	Missense	distal	5	no	6.530	6.410	EPSD	COSMIC	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q9UQ35	SRRM2	O14757	CHEK1	S901	P897S	897	Missense	distal	-4	no	6.530	6.293	EPSD	COSMIC	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q9UQ35	SRRM2	O14757	CHEK1	S929	S931C	931	Missense	proximal	2	no	8.316	7.955	EPSD	COSMIC	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q9UQ35	SRRM2	O14757	CHEK1	S929	P925L	925	Missense	distal	-4	no	8.316	8.132	EPSD	COSMIC	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q9UQ35	SRRM2	O14757	CHEK1	S1101	S1101F	1101	Missense	central	0	yes	6.646	0.000	EPSD	COSMIC	5.604	Loss
CAMK_CAMKL_CHK1_CHEK1_ST	Q9UQ35	SRRM2	O14757	CHEK1	S1101	S1103Y	1103	Missense	proximal	2	no	6.646	6.349	EPSD	COSMIC	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q9UQ35	SRRM2	O14757	CHEK1	S1101	R1098Q	1098	Missense	distal	-3	no	6.646	-0.561	EPSD	COSMIC	5.604	Loss
CAMK_CAMKL_CHK1_CHEK1_ST	Q9UQ35	SRRM2	O14757	CHEK1	S1140	S1144L	1144	Missense	distal	4	no	6.166	6.203	EPSD	COSMIC	5.604	Up-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q9UQ35	SRRM2	O14757	CHEK1	S1214	P1209L	1209	Missense	distal	-5	no	6.835	11.541	EPSD	COSMIC	5.604	Up-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q9UQ35	SRRM2	O14757	CHEK1	S1214	P1209S	1209	Missense	distal	-5	no	6.835	8.353	EPSD	COSMIC	5.604	Up-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q9UQ35	SRRM2	O14757	CHEK1	S1214	G1217W	1217	Missense	distal	3	no	6.835	6.781	EPSD	COSMIC	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q9UQ35	SRRM2	O14757	CHEK1	S1214	G1217R	1217	Missense	distal	3	no	6.835	6.919	EPSD	COSMIC	5.604	Up-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q9UQ35	SRRM2	O14757	CHEK1	S1266	M1263T	1263	Missense	distal	-3	no	6.016	-9.404	EPSD	COSMIC;GDSC;CCLE	5.604	Loss
CAMK_CAMKL_CHK1_CHEK1_ST	Q9UQ35	SRRM2	O14757	CHEK1	S1266	N1267D	1267	Missense	proximal	1	no	6.016	6.124	EPSD	COSMIC	5.604	Up-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q9UQ35	SRRM2	O14757	CHEK1	S1415	S1415L	1415	Missense	central	0	yes	7.237	0.000	EPSD	COSMIC	5.604	Loss
CAMK_CAMKL_CHK1_CHEK1_ST	Q9UQ35	SRRM2	O14757	CHEK1	S1415	E1417K	1417	Missense	proximal	2	no	7.237	7.279	EPSD	COSMIC	5.604	Up-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q9UQ35	SRRM2	O14757	CHEK1	S1415	V1410I	1410	Missense	distal	-5	no	7.237	8.682	EPSD	COSMIC	5.604	Up-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q9UQ35	SRRM2	O14757	CHEK1	S1415	S1419R	1419	Missense	distal	4	no	7.237	7.287	EPSD	COSMIC;GDSC;CCLE	5.604	Up-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q9UQ35	SRRM2	O14757	CHEK1	S1419	S1415L	1415	Missense	distal	-4	no	8.175	8.227	EPSD	COSMIC	5.604	Up-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q9UQ35	SRRM2	O14757	CHEK1	S1419	E1417K	1417	Missense	proximal	-2	no	8.175	8.032	EPSD	COSMIC	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q9UQ35	SRRM2	O14757	CHEK1	S1419	S1419R	1419	Missense	central	0	yes	8.175	0.000	EPSD	COSMIC;GDSC;CCLE	5.604	Loss
CAMK_CAMKL_CHK1_CHEK1_ST	Q9UQ35	SRRM2	O14757	CHEK1	S1421	S1415L	1415	Missense	distal	-6	no	6.266	6.291	EPSD	COSMIC	5.604	Up-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q9UQ35	SRRM2	O14757	CHEK1	S1421	E1417K	1417	Missense	distal	-4	no	6.266	6.164	EPSD	COSMIC	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q9UQ35	SRRM2	O14757	CHEK1	S1421	S1419R	1419	Missense	proximal	-2	no	6.266	6.366	EPSD	COSMIC;GDSC;CCLE	5.604	Up-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q9UQ35	SRRM2	O14757	CHEK1	S1436	G1430D	1430	Missense	distal	-6	no	12.624	12.414	EPSD	COSMIC	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q9UQ35	SRRM2	O14757	CHEK1	S1436	R1437S	1437	Missense	proximal	1	no	12.624	12.598	EPSD	COSMIC	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q9UQ35	SRRM2	O14757	CHEK1	S1441	S1444F	1444	Missense	distal	3	no	7.836	8.024	EPSD	COSMIC;GDSC;CCLE	5.604	Up-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q9UQ35	SRRM2	O14757	CHEK1	S1441	R1437S	1437	Missense	distal	-4	no	7.836	7.528	EPSD	COSMIC	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q9UQ35	SRRM2	O14757	CHEK1	S1441	R1437K	1437	Missense	distal	-4	no	7.836	7.937	EPSD	COSMIC	5.604	Up-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q9UQ35	SRRM2	O14757	CHEK1	S1443	S1444F	1444	Missense	proximal	1	no	5.936	5.931	EPSD	COSMIC;GDSC;CCLE	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q9UQ35	SRRM2	O14757	CHEK1	S1443	R1437S	1437	Missense	distal	-6	no	5.936	6.016	EPSD	COSMIC	5.604	Up-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q9UQ35	SRRM2	O14757	CHEK1	S1443	R1437K	1437	Missense	distal	-6	no	5.936	5.926	EPSD	COSMIC	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q9UQ35	SRRM2	O14757	CHEK1	S1451	S1444F	1444	Missense	distal	-7	no	9.066	7.334	EPSD	COSMIC;GDSC;CCLE	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q9UQ35	SRRM2	O14757	CHEK1	S1451	P1454L	1454	Missense	distal	3	no	9.066	8.302	EPSD	COSMIC	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q9UQ35	SRRM2	O14757	CHEK1	S1474	R1475G	1475	Missense	proximal	1	no	10.843	10.835	EPSD	COSMIC	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q9UQ35	SRRM2	O14757	CHEK1	S1474	S1474F	1474	Missense	central	0	yes	10.843	0.000	EPSD	COSMIC	5.604	Loss
CAMK_CAMKL_CHK1_CHEK1_ST	Q9UQ35	SRRM2	O14757	CHEK1	S1478	R1475G	1475	Missense	distal	-3	no	8.662	0.888	EPSD	COSMIC	5.604	Loss
CAMK_CAMKL_CHK1_CHEK1_ST	Q9UQ35	SRRM2	O14757	CHEK1	S1478	S1474F	1474	Missense	distal	-4	no	8.662	8.420	EPSD	COSMIC	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q9UQ35	SRRM2	O14757	CHEK1	S1478	S1483F	1483	Missense	distal	5	no	8.662	8.337	EPSD	COSMIC	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q9UQ35	SRRM2	O14757	CHEK1	S1497	R1498H	1498	Missense	proximal	1	no	7.995	7.929	EPSD;PhosphoSitePlus	COSMIC;GDSC;CCLE	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q9UQ35	SRRM2	O14757	CHEK1	S1497	S1502F	1502	Missense	distal	5	no	7.995	7.670	EPSD;PhosphoSitePlus	COSMIC	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q9UQ35	SRRM2	O14757	CHEK1	S1499	R1498H	1498	Missense	proximal	-1	no	8.804	8.930	EPSD;PhosphoSitePlus	COSMIC;GDSC;CCLE	5.604	Up-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q9UQ35	SRRM2	O14757	CHEK1	S1499	S1502F	1502	Missense	distal	3	no	8.804	8.993	EPSD;PhosphoSitePlus	COSMIC	5.604	Up-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q9UQ35	SRRM2	O14757	CHEK1	S1501	R1498H	1498	Missense	distal	-3	no	8.668	2.859	EPSD	COSMIC;GDSC;CCLE	5.604	Loss
CAMK_CAMKL_CHK1_CHEK1_ST	Q9UQ35	SRRM2	O14757	CHEK1	S1501	S1502F	1502	Missense	proximal	1	no	8.668	8.663	EPSD	COSMIC	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q9UQ35	SRRM2	O14757	CHEK1	S1517	D1524H	1524	Missense	distal	7	no	7.818	7.227	EPSD	COSMIC	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q9UQ35	SRRM2	O14757	CHEK1	S1519	D1524H	1524	Missense	distal	5	no	7.222	7.048	EPSD	COSMIC	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q9UQ35	SRRM2	O14757	CHEK1	S1539	D1546G	1546	Missense	distal	7	no	7.300	7.007	EPSD	COSMIC	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q9UQ35	SRRM2	O14757	CHEK1	S1541	D1546G	1546	Missense	distal	5	no	8.184	7.906	EPSD	COSMIC	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q9UQ35	SRRM2	O14757	CHEK1	S1577	R1574W	1574	Missense	distal	-3	no	7.120	-26.483	EPSD	COSMIC	5.604	Loss
CAMK_CAMKL_CHK1_CHEK1_ST	Q9UQ35	SRRM2	O14757	CHEK1	S1577	R1578Q	1578	Missense	proximal	1	no	7.120	7.129	EPSD	COSMIC;GDSC	5.604	Up-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q9UQ35	SRRM2	O14757	CHEK1	S1579	R1574W	1574	Missense	distal	-5	no	7.043	6.184	EPSD	COSMIC	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q9UQ35	SRRM2	O14757	CHEK1	S1579	R1578Q	1578	Missense	proximal	-1	no	7.043	7.058	EPSD	COSMIC;GDSC	5.604	Up-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q9UQ35	SRRM2	O14757	CHEK1	S1581	R1574W	1574	Missense	distal	-7	no	7.711	6.166	EPSD	COSMIC	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q9UQ35	SRRM2	O14757	CHEK1	S1581	R1578Q	1578	Missense	distal	-3	no	7.711	0.504	EPSD	COSMIC;GDSC	5.604	Loss
CAMK_CAMKL_CHK1_CHEK1_ST	Q9UQ35	SRRM2	O14757	CHEK1	S1596	R1595H	1595	Missense	proximal	-1	no	6.205	6.330	EPSD	COSMIC	5.604	Up-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q9UQ35	SRRM2	O14757	CHEK1	S1596	S1601P	1601	Missense	distal	5	no	6.205	6.123	EPSD	COSMIC	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q9UQ35	SRRM2	O14757	CHEK1	S1598	R1595H	1595	Missense	distal	-3	no	6.624	0.815	EPSD	COSMIC	5.604	Loss
CAMK_CAMKL_CHK1_CHEK1_ST	Q9UQ35	SRRM2	O14757	CHEK1	S1598	S1601P	1601	Missense	distal	3	no	6.624	6.953	EPSD	COSMIC	5.604	Up-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q9UQ35	SRRM2	O14757	CHEK1	S1600	R1595H	1595	Missense	distal	-5	no	8.519	6.054	EPSD	COSMIC	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q9UQ35	SRRM2	O14757	CHEK1	S1600	S1601P	1601	Missense	proximal	1	no	8.519	8.482	EPSD	COSMIC	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q9UQ35	SRRM2	O14757	CHEK1	S1616	P1622L	1622	Missense	distal	6	no	8.302	8.092	EPSD	COSMIC	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q9UQ35	SRRM2	O14757	CHEK1	S1638	R1637G	1637	Missense	proximal	-1	no	7.683	7.700	EPSD	COSMIC	5.604	Up-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q9UQ35	SRRM2	O14757	CHEK1	S1638	P1633L	1633	Missense	distal	-5	no	7.683	12.390	EPSD	COSMIC	5.604	Up-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q9UQ35	SRRM2	O14757	CHEK1	S1640	R1637G	1637	Missense	distal	-3	no	7.474	-0.300	EPSD	COSMIC	5.604	Loss
CAMK_CAMKL_CHK1_CHEK1_ST	Q9UQ35	SRRM2	O14757	CHEK1	S1640	P1633L	1633	Missense	distal	-7	no	7.474	7.260	EPSD	COSMIC	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q9UQ35	SRRM2	O14757	CHEK1	S1648	T1655I	1655	Missense	distal	7	no	12.260	12.035	EPSD	COSMIC	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q9UQ35	SRRM2	O14757	CHEK1	S1672	S1674P	1674	Missense	proximal	2	no	10.112	10.035	EPSD	COSMIC;GDSC;CCLE	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q9UQ35	SRRM2	O14757	CHEK1	S1672	P1676Q	1676	Missense	distal	4	no	10.112	10.022	EPSD	COSMIC	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q9UQ35	SRRM2	O14757	CHEK1	S1690	E1696K	1696	Missense	distal	6	no	6.896	7.165	EPSD	COSMIC	5.604	Up-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q9UQ35	SRRM2	O14757	CHEK1	S1690	R1688H	1688	Missense	proximal	-2	no	6.896	6.960	EPSD	COSMIC	5.604	Up-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q9UQ35	SRRM2	O14757	CHEK1	S1691	E1696K	1696	Missense	distal	5	no	5.807	5.742	EPSD	COSMIC	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q9UQ35	SRRM2	O14757	CHEK1	S1691	R1688H	1688	Missense	distal	-3	no	5.807	-0.002	EPSD	COSMIC	5.604	Loss
CAMK_CAMKL_CHK1_CHEK1_ST	Q9UQ35	SRRM2	O14757	CHEK1	S1711	A1710V	1710	Missense	proximal	-1	no	6.961	6.883	EPSD	COSMIC;GDSC;CCLE	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q9UQ35	SRRM2	O14757	CHEK1	S1711	R1706K	1706	Missense	distal	-5	no	6.961	8.137	EPSD	COSMIC	5.604	Up-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q9UQ35	SRRM2	O14757	CHEK1	S1711	R1705C	1705	Missense	distal	-6	no	6.961	7.077	EPSD	COSMIC	5.604	Up-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q9UQ35	SRRM2	O14757	CHEK1	T1720	P1721S	1721	Missense	proximal	1	no	7.375	7.412	EPSD	COSMIC	5.604	Up-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q9UQ35	SRRM2	O14757	CHEK1	S1729	E1734K	1734	Missense	distal	5	no	6.212	6.147	EPSD	COSMIC	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q9UQ35	SRRM2	O14757	CHEK1	S1747	S1741C	1741	Missense	distal	-6	no	10.408	10.443	EPSD	COSMIC;GDSC;CCLE	5.604	Up-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q9UQ35	SRRM2	O14757	CHEK1	S1762	K1766T	1766	Missense	distal	4	no	7.307	7.366	EPSD	COSMIC	5.604	Up-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q9UQ35	SRRM2	O14757	CHEK1	S1762	R1758W	1758	Missense	distal	-4	no	7.307	6.545	EPSD	COSMIC	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q9UQ35	SRRM2	O14757	CHEK1	S1762	R1761L	1761	Missense	proximal	-1	no	7.307	7.406	EPSD	COSMIC;CCLE	5.604	Up-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q9UQ35	SRRM2	O14757	CHEK1	S1762	G1760V	1760	Missense	proximal	-2	no	7.307	7.365	EPSD	COSMIC	5.604	Up-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q9UQ35	SRRM2	O14757	CHEK1	S1764	K1766T	1766	Missense	proximal	2	no	10.026	9.043	EPSD	COSMIC	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q9UQ35	SRRM2	O14757	CHEK1	S1764	R1758W	1758	Missense	distal	-6	no	10.026	10.346	EPSD	COSMIC	5.604	Up-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q9UQ35	SRRM2	O14757	CHEK1	S1764	R1761L	1761	Missense	distal	-3	no	10.026	-8.521	EPSD	COSMIC;CCLE	5.604	Loss
CAMK_CAMKL_CHK1_CHEK1_ST	Q9UQ35	SRRM2	O14757	CHEK1	S1764	G1760V	1760	Missense	distal	-4	no	10.026	9.992	EPSD	COSMIC	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q9UQ35	SRRM2	O14757	CHEK1	S1775	R1779T	1779	Missense	distal	4	no	13.234	13.194	EPSD	COSMIC	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q9UQ35	SRRM2	O14757	CHEK1	T1784	R1788Q	1788	Missense	distal	4	no	6.236	6.235	EPSD	COSMIC;CCLE	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q9UQ35	SRRM2	O14757	CHEK1	T1784	R1779T	1779	Missense	distal	-5	no	6.236	7.157	EPSD	COSMIC	5.604	Up-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q9UQ35	SRRM2	O14757	CHEK1	S1791	R1788Q	1788	Missense	distal	-3	no	9.800	2.593	EPSD	COSMIC;CCLE	5.604	Loss
CAMK_CAMKL_CHK1_CHEK1_ST	Q9UQ35	SRRM2	O14757	CHEK1	S1791	S1796P	1796	Missense	distal	5	no	9.800	9.718	EPSD	COSMIC	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q9UQ35	SRRM2	O14757	CHEK1	S1793	R1788Q	1788	Missense	distal	-5	no	10.373	9.977	EPSD	COSMIC;CCLE	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q9UQ35	SRRM2	O14757	CHEK1	S1793	S1796P	1796	Missense	distal	3	no	10.373	10.702	EPSD	COSMIC	5.604	Up-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q9UQ35	SRRM2	O14757	CHEK1	S1818	R1814Q	1814	Missense	distal	-4	no	9.078	9.238	EPSD	COSMIC	5.604	Up-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q9UQ35	SRRM2	O14757	CHEK1	S1830	E1829K	1829	Missense	proximal	-1	no	8.697	8.639	EPSD	COSMIC	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q9UQ35	SRRM2	O14757	CHEK1	S1842	R1839S	1839	Missense	distal	-3	no	9.900	0.204	EPSD	COSMIC	5.604	Loss
CAMK_CAMKL_CHK1_CHEK1_ST	Q9UQ35	SRRM2	O14757	CHEK1	S1842	R1838Q	1838	Missense	distal	-4	no	9.900	10.060	EPSD	COSMIC	5.604	Up-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q9UQ35	SRRM2	O14757	CHEK1	T1844	R1839S	1839	Missense	distal	-5	no	8.740	8.529	EPSD	COSMIC	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q9UQ35	SRRM2	O14757	CHEK1	T1844	R1838Q	1838	Missense	distal	-6	no	8.740	8.822	EPSD	COSMIC	5.604	Up-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q9UQ35	SRRM2	O14757	CHEK1	S1852	R1855S	1855	Missense	distal	3	no	8.816	8.819	EPSD	COSMIC	5.604	Up-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q9UQ35	SRRM2	O14757	CHEK1	S1852	R1855C	1855	Missense	distal	3	no	8.816	7.869	EPSD	COSMIC;GDSC;CCLE	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q9UQ35	SRRM2	O14757	CHEK1	S1852	R1853H	1853	Missense	proximal	1	no	8.816	8.751	EPSD	COSMIC	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q9UQ35	SRRM2	O14757	CHEK1	S1854	R1855S	1855	Missense	proximal	1	no	8.432	8.406	EPSD	COSMIC	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q9UQ35	SRRM2	O14757	CHEK1	S1854	R1855C	1855	Missense	proximal	1	no	8.432	8.422	EPSD	COSMIC;GDSC;CCLE	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q9UQ35	SRRM2	O14757	CHEK1	S1854	R1853H	1853	Missense	proximal	-1	no	8.432	8.558	EPSD	COSMIC	5.604	Up-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q9UQ35	SRRM2	O14757	CHEK1	T1856	R1855S	1855	Missense	proximal	-1	no	8.195	8.034	EPSD	COSMIC	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q9UQ35	SRRM2	O14757	CHEK1	T1856	R1855C	1855	Missense	proximal	-1	no	8.195	8.230	EPSD	COSMIC;GDSC;CCLE	5.604	Up-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q9UQ35	SRRM2	O14757	CHEK1	T1856	R1853H	1853	Missense	distal	-3	no	8.195	2.386	EPSD	COSMIC	5.604	Loss
CAMK_CAMKL_CHK1_CHEK1_ST	Q9UQ35	SRRM2	O14757	CHEK1	S1866	A1868V	1868	Missense	proximal	2	no	10.039	9.476	EPSD	COSMIC	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q9UQ35	SRRM2	O14757	CHEK1	S1878	S1878F	1878	Missense	central	0	yes	6.953	0.000	EPSD	COSMIC	5.604	Loss
CAMK_CAMKL_CHK1_CHEK1_ST	Q9UQ35	SRRM2	O14757	CHEK1	S1878	R1874Q	1874	Missense	distal	-4	no	6.953	7.113	EPSD	COSMIC	5.604	Up-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q9UQ35	SRRM2	O14757	CHEK1	T1880	S1878F	1878	Missense	proximal	-2	no	6.239	6.528	EPSD	COSMIC	5.604	Up-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q9UQ35	SRRM2	O14757	CHEK1	T1880	R1886H	1886	Missense	distal	6	no	6.239	6.527	EPSD	COSMIC	5.604	Up-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q9UQ35	SRRM2	O14757	CHEK1	T1880	R1874Q	1874	Missense	distal	-6	no	6.239	6.321	EPSD	COSMIC	5.604	Up-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q9UQ35	SRRM2	O14757	CHEK1	S1888	P1894Q	1894	Missense	distal	6	no	10.205	9.667	EPSD	COSMIC	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q9UQ35	SRRM2	O14757	CHEK1	S1888	V1895A	1895	Missense	distal	7	no	10.205	10.126	EPSD	COSMIC	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q9UQ35	SRRM2	O14757	CHEK1	S1888	R1886H	1886	Missense	proximal	-2	no	10.205	10.270	EPSD	COSMIC	5.604	Up-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q9UQ35	SRRM2	O14757	CHEK1	S1888	P1894S	1894	Missense	distal	6	no	10.205	9.586	EPSD	COSMIC	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q9UQ35	SRRM2	O14757	CHEK1	S1890	P1894Q	1894	Missense	distal	4	no	7.529	7.439	EPSD	COSMIC	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q9UQ35	SRRM2	O14757	CHEK1	S1890	V1895A	1895	Missense	distal	5	no	7.529	7.632	EPSD	COSMIC	5.604	Up-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q9UQ35	SRRM2	O14757	CHEK1	S1890	R1886H	1886	Missense	distal	-4	no	7.529	7.331	EPSD	COSMIC	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q9UQ35	SRRM2	O14757	CHEK1	S1890	P1894S	1894	Missense	distal	4	no	7.529	7.389	EPSD	COSMIC	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q9UQ35	SRRM2	O14757	CHEK1	T1892	R1899L	1899	Missense	distal	7	no	8.214	8.113	EPSD	COSMIC	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q9UQ35	SRRM2	O14757	CHEK1	T1892	P1894Q	1894	Missense	proximal	2	no	8.214	8.724	EPSD	COSMIC	5.604	Up-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q9UQ35	SRRM2	O14757	CHEK1	T1892	V1895A	1895	Missense	distal	3	no	8.214	7.969	EPSD	COSMIC	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q9UQ35	SRRM2	O14757	CHEK1	T1892	R1886H	1886	Missense	distal	-6	no	8.214	8.323	EPSD	COSMIC	5.604	Up-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q9UQ35	SRRM2	O14757	CHEK1	T1892	P1894S	1894	Missense	proximal	2	no	8.214	8.290	EPSD	COSMIC	5.604	Up-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q9UQ35	SRRM2	O14757	CHEK1	S1900	R1899L	1899	Missense	proximal	-1	no	8.678	8.777	EPSD	COSMIC	5.604	Up-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q9UQ35	SRRM2	O14757	CHEK1	S1900	P1894Q	1894	Missense	distal	-6	no	8.678	8.582	EPSD	COSMIC	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q9UQ35	SRRM2	O14757	CHEK1	S1900	V1895A	1895	Missense	distal	-5	no	8.678	6.239	EPSD	COSMIC	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q9UQ35	SRRM2	O14757	CHEK1	S1900	S1902Y	1902	Missense	proximal	2	no	8.678	8.381	EPSD	COSMIC;GDSC;CCLE	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q9UQ35	SRRM2	O14757	CHEK1	S1900	P1894S	1894	Missense	distal	-6	no	8.678	8.581	EPSD	COSMIC	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q9UQ35	SRRM2	O14757	CHEK1	S1902	R1899L	1899	Missense	distal	-3	no	8.410	-10.136	EPSD	COSMIC	5.604	Loss
CAMK_CAMKL_CHK1_CHEK1_ST	Q9UQ35	SRRM2	O14757	CHEK1	S1902	V1895A	1895	Missense	distal	-7	no	8.410	9.067	EPSD	COSMIC	5.604	Up-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q9UQ35	SRRM2	O14757	CHEK1	S1902	S1902Y	1902	Missense	central	0	yes	8.410	0.000	EPSD	COSMIC;GDSC;CCLE	5.604	Loss
CAMK_CAMKL_CHK1_CHEK1_ST	Q9UQ35	SRRM2	O14757	CHEK1	T1904	R1899L	1899	Missense	distal	-5	no	8.797	11.773	EPSD	COSMIC	5.604	Up-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q9UQ35	SRRM2	O14757	CHEK1	T1904	S1902Y	1902	Missense	proximal	-2	no	8.797	8.909	EPSD	COSMIC;GDSC;CCLE	5.604	Up-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q9UQ35	SRRM2	O14757	CHEK1	S1923	R1921G	1921	Missense	proximal	-2	no	9.000	9.034	EPSD	COSMIC	5.604	Up-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q9UQ35	SRRM2	O14757	CHEK1	S1925	R1921G	1921	Missense	distal	-4	no	10.440	10.467	EPSD	COSMIC	5.604	Up-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q9UQ35	SRRM2	O14757	CHEK1	T1927	R1921G	1921	Missense	distal	-6	no	9.219	9.337	EPSD	COSMIC	5.604	Up-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q9UQ35	SRRM2	O14757	CHEK1	S1935	R1938T	1938	Missense	distal	3	no	7.026	6.885	EPSD	COSMIC	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q9UQ35	SRRM2	O14757	CHEK1	S1937	R1938T	1938	Missense	proximal	1	no	8.934	8.916	EPSD	COSMIC	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q9UQ35	SRRM2	O14757	CHEK1	S1937	R1944H	1944	Missense	distal	7	no	8.934	8.641	EPSD	COSMIC	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q9UQ35	SRRM2	O14757	CHEK1	T1939	R1938T	1938	Missense	proximal	-1	no	8.050	8.093	EPSD	COSMIC	5.604	Up-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q9UQ35	SRRM2	O14757	CHEK1	T1939	R1945H	1945	Missense	distal	6	no	8.050	8.338	EPSD	COSMIC	5.604	Up-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q9UQ35	SRRM2	O14757	CHEK1	T1939	R1944H	1944	Missense	distal	5	no	8.050	8.066	EPSD	COSMIC	5.604	Up-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q9UQ35	SRRM2	O14757	CHEK1	T1941	R1938T	1938	Missense	distal	-3	no	10.178	-10.391	EPSD	COSMIC	5.604	Loss
CAMK_CAMKL_CHK1_CHEK1_ST	Q9UQ35	SRRM2	O14757	CHEK1	T1941	R1947L	1947	Missense	distal	6	no	10.178	10.500	EPSD	COSMIC	5.604	Up-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q9UQ35	SRRM2	O14757	CHEK1	T1941	R1945H	1945	Missense	distal	4	no	10.178	10.339	EPSD	COSMIC	5.604	Up-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q9UQ35	SRRM2	O14757	CHEK1	T1941	R1944H	1944	Missense	distal	3	no	10.178	10.208	EPSD	COSMIC	5.604	Up-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q9UQ35	SRRM2	O14757	CHEK1	T1941	R1947H	1947	Missense	distal	6	no	10.178	10.466	EPSD	COSMIC	5.604	Up-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q9UQ35	SRRM2	O14757	CHEK1	S1946	R1947L	1947	Missense	proximal	1	no	11.287	11.252	EPSD	COSMIC	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q9UQ35	SRRM2	O14757	CHEK1	S1946	R1945H	1945	Missense	proximal	-1	no	11.287	11.413	EPSD	COSMIC	5.604	Up-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q9UQ35	SRRM2	O14757	CHEK1	S1946	R1944H	1944	Missense	proximal	-2	no	11.287	11.352	EPSD	COSMIC	5.604	Up-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q9UQ35	SRRM2	O14757	CHEK1	S1946	R1947H	1947	Missense	proximal	1	no	11.287	11.222	EPSD	COSMIC	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q9UQ35	SRRM2	O14757	CHEK1	S1946	P1951S	1951	Missense	distal	5	no	11.287	11.369	EPSD	COSMIC	5.604	Up-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q9UQ35	SRRM2	O14757	CHEK1	S1948	R1947L	1947	Missense	proximal	-1	no	10.690	10.789	EPSD	COSMIC	5.604	Up-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q9UQ35	SRRM2	O14757	CHEK1	S1948	R1945H	1945	Missense	distal	-3	no	10.690	4.881	EPSD	COSMIC	5.604	Loss
CAMK_CAMKL_CHK1_CHEK1_ST	Q9UQ35	SRRM2	O14757	CHEK1	S1948	R1944H	1944	Missense	distal	-4	no	10.690	10.493	EPSD	COSMIC	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q9UQ35	SRRM2	O14757	CHEK1	S1948	R1947H	1947	Missense	proximal	-1	no	10.690	10.815	EPSD	COSMIC	5.604	Up-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q9UQ35	SRRM2	O14757	CHEK1	S1948	P1951S	1951	Missense	distal	3	no	10.690	10.360	EPSD	COSMIC	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q9UQ35	SRRM2	O14757	CHEK1	T1950	R1947L	1947	Missense	distal	-3	no	9.383	-9.163	EPSD	COSMIC	5.604	Loss
CAMK_CAMKL_CHK1_CHEK1_ST	Q9UQ35	SRRM2	O14757	CHEK1	T1950	R1945H	1945	Missense	distal	-5	no	9.383	6.918	EPSD	COSMIC	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q9UQ35	SRRM2	O14757	CHEK1	T1950	R1944H	1944	Missense	distal	-6	no	9.383	9.493	EPSD	COSMIC	5.604	Up-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q9UQ35	SRRM2	O14757	CHEK1	T1950	R1947H	1947	Missense	distal	-3	no	9.383	3.574	EPSD	COSMIC	5.604	Loss
CAMK_CAMKL_CHK1_CHEK1_ST	Q9UQ35	SRRM2	O14757	CHEK1	T1950	P1951S	1951	Missense	proximal	1	no	9.383	9.420	EPSD	COSMIC	5.604	Up-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q9UQ35	SRRM2	O14757	CHEK1	S1958	S1958F	1958	Missense	central	0	yes	10.255	0.000	EPSD	COSMIC	5.604	Loss
CAMK_CAMKL_CHK1_CHEK1_ST	Q9UQ35	SRRM2	O14757	CHEK1	S1958	P1951S	1951	Missense	distal	-7	no	10.255	10.924	EPSD	COSMIC	5.604	Up-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q9UQ35	SRRM2	O14757	CHEK1	S1960	S1958F	1958	Missense	proximal	-2	no	11.578	11.868	EPSD	COSMIC	5.604	Up-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q9UQ35	SRRM2	O14757	CHEK1	S1960	R1967K	1967	Missense	distal	7	no	11.578	11.653	EPSD	COSMIC	5.604	Up-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q9UQ35	SRRM2	O14757	CHEK1	T1962	R1969Q	1969	Missense	distal	7	no	9.102	9.257	EPSD	COSMIC	5.604	Up-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q9UQ35	SRRM2	O14757	CHEK1	T1962	S1958F	1958	Missense	distal	-4	no	9.102	8.860	EPSD	COSMIC	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q9UQ35	SRRM2	O14757	CHEK1	T1962	R1967K	1967	Missense	distal	5	no	9.102	9.226	EPSD	COSMIC	5.604	Up-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q9UQ35	SRRM2	O14757	CHEK1	S1970	R1969Q	1969	Missense	proximal	-1	no	9.380	9.395	EPSD	COSMIC	5.604	Up-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q9UQ35	SRRM2	O14757	CHEK1	S1970	R1967K	1967	Missense	distal	-3	no	9.380	5.555	EPSD	COSMIC	5.604	Loss
CAMK_CAMKL_CHK1_CHEK1_ST	Q9UQ35	SRRM2	O14757	CHEK1	S1972	R1969Q	1969	Missense	distal	-3	no	9.850	2.643	EPSD	COSMIC	5.604	Loss
CAMK_CAMKL_CHK1_CHEK1_ST	Q9UQ35	SRRM2	O14757	CHEK1	S1972	R1967K	1967	Missense	distal	-5	no	9.850	11.025	EPSD	COSMIC	5.604	Up-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q9UQ35	SRRM2	O14757	CHEK1	T1974	R1969Q	1969	Missense	distal	-5	no	8.174	7.778	EPSD	COSMIC	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q9UQ35	SRRM2	O14757	CHEK1	T1974	R1967K	1967	Missense	distal	-7	no	8.174	9.354	EPSD	COSMIC	5.604	Up-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q9UQ35	SRRM2	O14757	CHEK1	S1994	S1996F	1996	Missense	proximal	2	no	10.602	10.457	EPSD	COSMIC	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q9UQ35	SRRM2	O14757	CHEK1	S1996	S1996F	1996	Missense	central	0	yes	9.955	0.000	EPSD	COSMIC	5.604	Loss
CAMK_CAMKL_CHK1_CHEK1_ST	Q9UQ35	SRRM2	O14757	CHEK1	T1998	S1996F	1996	Missense	proximal	-2	no	8.160	8.449	EPSD	COSMIC	5.604	Up-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q9UQ35	SRRM2	O14757	CHEK1	S2006	R2007H	2007	Missense	proximal	1	no	11.305	11.239	EPSD	COSMIC	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q9UQ35	SRRM2	O14757	CHEK1	S2006	R2009Q	2009	Missense	distal	3	no	11.305	12.367	EPSD	COSMIC	5.604	Up-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q9UQ35	SRRM2	O14757	CHEK1	S2008	R2007H	2007	Missense	proximal	-1	no	10.311	10.436	EPSD	COSMIC	5.604	Up-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q9UQ35	SRRM2	O14757	CHEK1	S2008	R2009Q	2009	Missense	proximal	1	no	10.311	10.319	EPSD	COSMIC	5.604	Up-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q9UQ35	SRRM2	O14757	CHEK1	T2010	R2007H	2007	Missense	distal	-3	no	7.039	1.230	EPSD	COSMIC	5.604	Loss
CAMK_CAMKL_CHK1_CHEK1_ST	Q9UQ35	SRRM2	O14757	CHEK1	T2010	R2017C	2017	Missense	distal	7	no	7.039	6.634	EPSD	COSMIC	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q9UQ35	SRRM2	O14757	CHEK1	T2010	R2009Q	2009	Missense	proximal	-1	no	7.039	7.055	EPSD	COSMIC	5.604	Up-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q9UQ35	SRRM2	O14757	CHEK1	S2018	S2018F	2018	Missense	central	0	yes	10.226	0.000	EPSD	COSMIC	5.604	Loss
CAMK_CAMKL_CHK1_CHEK1_ST	Q9UQ35	SRRM2	O14757	CHEK1	S2018	R2017C	2017	Missense	proximal	-1	no	10.226	10.261	EPSD	COSMIC	5.604	Up-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q9UQ35	SRRM2	O14757	CHEK1	S2020	S2018F	2018	Missense	proximal	-2	no	10.148	10.438	EPSD	COSMIC	5.604	Up-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q9UQ35	SRRM2	O14757	CHEK1	S2020	R2017C	2017	Missense	distal	-3	no	10.148	2.057	EPSD	COSMIC	5.604	Loss
CAMK_CAMKL_CHK1_CHEK1_ST	Q9UQ35	SRRM2	O14757	CHEK1	T2022	S2018F	2018	Missense	distal	-4	no	7.122	6.880	EPSD	COSMIC	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q9UQ35	SRRM2	O14757	CHEK1	T2022	R2017C	2017	Missense	distal	-5	no	7.122	6.444	EPSD	COSMIC	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q9UQ35	SRRM2	O14757	CHEK1	S2030	R2033Q	2033	Missense	distal	3	no	8.049	9.111	EPSD	COSMIC	5.604	Up-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q9UQ35	SRRM2	O14757	CHEK1	S2032	R2033Q	2033	Missense	proximal	1	no	12.257	12.265	EPSD	COSMIC	5.604	Up-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q9UQ35	SRRM2	O14757	CHEK1	S2032	R2039C	2039	Missense	distal	7	no	12.257	11.851	EPSD	COSMIC	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q9UQ35	SRRM2	O14757	CHEK1	T2034	R2033Q	2033	Missense	proximal	-1	no	6.689	6.704	EPSD	COSMIC	5.604	Up-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q9UQ35	SRRM2	O14757	CHEK1	T2034	R2039C	2039	Missense	distal	5	no	6.689	6.445	EPSD	COSMIC	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q9UQ35	SRRM2	O14757	CHEK1	S2042	A2049V	2049	Missense	distal	7	no	12.881	12.960	EPSD	COSMIC	5.604	Up-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q9UQ35	SRRM2	O14757	CHEK1	S2042	A2049G	2049	Missense	distal	7	no	12.881	12.930	EPSD	COSMIC	5.604	Up-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q9UQ35	SRRM2	O14757	CHEK1	S2042	A2049P	2049	Missense	distal	7	no	12.881	12.887	EPSD	COSMIC	5.604	Up-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q9UQ35	SRRM2	O14757	CHEK1	S2042	L2048V	2048	Missense	distal	6	no	12.881	12.748	EPSD	COSMIC;GDSC;CCLE	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q9UQ35	SRRM2	O14757	CHEK1	S2042	R2039C	2039	Missense	distal	-3	no	12.881	4.790	EPSD	COSMIC	5.604	Loss
CAMK_CAMKL_CHK1_CHEK1_ST	Q9UQ35	SRRM2	O14757	CHEK1	S2044	A2049V	2049	Missense	distal	5	no	9.101	8.998	EPSD	COSMIC	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q9UQ35	SRRM2	O14757	CHEK1	S2044	A2049G	2049	Missense	distal	5	no	9.101	8.892	EPSD	COSMIC	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q9UQ35	SRRM2	O14757	CHEK1	S2044	A2049P	2049	Missense	distal	5	no	9.101	9.001	EPSD	COSMIC	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q9UQ35	SRRM2	O14757	CHEK1	S2044	L2048V	2048	Missense	distal	4	no	9.101	9.176	EPSD	COSMIC;GDSC;CCLE	5.604	Up-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q9UQ35	SRRM2	O14757	CHEK1	S2044	R2039C	2039	Missense	distal	-5	no	9.101	8.423	EPSD	COSMIC	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q9UQ35	SRRM2	O14757	CHEK1	S2046	A2049V	2049	Missense	distal	3	no	8.169	8.413	EPSD	COSMIC	5.604	Up-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q9UQ35	SRRM2	O14757	CHEK1	S2046	A2049G	2049	Missense	distal	3	no	8.169	7.987	EPSD	COSMIC	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q9UQ35	SRRM2	O14757	CHEK1	S2046	A2049P	2049	Missense	distal	3	no	8.169	8.404	EPSD	COSMIC	5.604	Up-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q9UQ35	SRRM2	O14757	CHEK1	S2046	L2048V	2048	Missense	proximal	2	no	8.169	8.456	EPSD	COSMIC;GDSC;CCLE	5.604	Up-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q9UQ35	SRRM2	O14757	CHEK1	S2046	R2039C	2039	Missense	distal	-7	no	8.169	7.441	EPSD	COSMIC	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q9UQ35	SRRM2	O14757	CHEK1	S2054	A2049V	2049	Missense	distal	-5	no	7.310	9.750	EPSD	COSMIC	5.604	Up-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q9UQ35	SRRM2	O14757	CHEK1	S2054	A2049G	2049	Missense	distal	-5	no	7.310	10.085	EPSD	COSMIC	5.604	Up-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q9UQ35	SRRM2	O14757	CHEK1	S2054	A2049P	2049	Missense	distal	-5	no	7.310	8.520	EPSD	COSMIC	5.604	Up-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q9UQ35	SRRM2	O14757	CHEK1	S2054	L2048V	2048	Missense	distal	-6	no	7.310	7.298	EPSD	COSMIC;GDSC;CCLE	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q9UQ35	SRRM2	O14757	CHEK1	S2054	T2058I	2058	Missense	distal	4	no	7.310	7.351	EPSD	COSMIC	5.604	Up-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q9UQ35	SRRM2	O14757	CHEK1	S2056	A2062D	2062	Missense	distal	6	no	10.857	10.285	EPSD	COSMIC	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q9UQ35	SRRM2	O14757	CHEK1	S2056	A2049V	2049	Missense	distal	-7	no	10.857	10.201	EPSD	COSMIC	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q9UQ35	SRRM2	O14757	CHEK1	S2056	A2049G	2049	Missense	distal	-7	no	10.857	10.186	EPSD	COSMIC	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q9UQ35	SRRM2	O14757	CHEK1	S2056	A2049P	2049	Missense	distal	-7	no	10.857	9.737	EPSD	COSMIC	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q9UQ35	SRRM2	O14757	CHEK1	S2056	T2058I	2058	Missense	proximal	2	no	10.857	10.742	EPSD	COSMIC	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q9UQ35	SRRM2	O14757	CHEK1	T2058	A2062D	2062	Missense	distal	4	no	7.889	7.746	EPSD	COSMIC	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q9UQ35	SRRM2	O14757	CHEK1	T2058	T2058I	2058	Missense	central	0	yes	7.889	0.000	EPSD	COSMIC	5.604	Loss
CAMK_CAMKL_CHK1_CHEK1_ST	Q9UQ35	SRRM2	O14757	CHEK1	T2069	A2062D	2062	Missense	distal	-7	no	9.104	8.424	EPSD	COSMIC	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q9UQ35	SRRM2	O14757	CHEK1	T2069	P2073S	2073	Missense	distal	4	no	9.104	8.964	EPSD	COSMIC	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q9UQ35	SRRM2	O14757	CHEK1	T2069	S2067P	2067	Missense	proximal	-2	no	9.104	9.388	EPSD	COSMIC	5.604	Up-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q9UQ35	SRRM2	O14757	CHEK1	T2069	A2074D	2074	Missense	distal	5	no	9.104	9.172	EPSD	COSMIC	5.604	Up-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q9UQ35	SRRM2	O14757	CHEK1	S2079	P2073S	2073	Missense	distal	-6	no	7.835	7.738	EPSD	COSMIC	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q9UQ35	SRRM2	O14757	CHEK1	S2079	R2078C	2078	Missense	proximal	-1	no	7.835	7.870	EPSD	COSMIC	5.604	Up-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q9UQ35	SRRM2	O14757	CHEK1	S2079	A2074D	2074	Missense	distal	-5	no	7.835	9.788	EPSD	COSMIC	5.604	Up-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q9UQ35	SRRM2	O14757	CHEK1	S2079	R2078H	2078	Missense	proximal	-1	no	7.835	7.961	EPSD	COSMIC	5.604	Up-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q9UQ35	SRRM2	O14757	CHEK1	S2081	R2078C	2078	Missense	distal	-3	no	10.233	2.142	EPSD	COSMIC	5.604	Loss
CAMK_CAMKL_CHK1_CHEK1_ST	Q9UQ35	SRRM2	O14757	CHEK1	S2081	A2074D	2074	Missense	distal	-7	no	10.233	9.553	EPSD	COSMIC	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q9UQ35	SRRM2	O14757	CHEK1	S2081	R2078H	2078	Missense	distal	-3	no	10.233	4.424	EPSD	COSMIC	5.604	Loss
CAMK_CAMKL_CHK1_CHEK1_ST	Q9UQ35	SRRM2	O14757	CHEK1	S2090	R2089Q	2089	Missense	proximal	-1	no	10.934	10.950	EPSD	COSMIC	5.604	Up-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q9UQ35	SRRM2	O14757	CHEK1	T2092	R2089Q	2089	Missense	distal	-3	no	7.816	0.609	EPSD	COSMIC	5.604	Loss
CAMK_CAMKL_CHK1_CHEK1_ST	Q9UQ35	SRRM2	O14757	CHEK1	S2147	T2144R	2144	Missense	distal	-3	no	-9.646	10.923	EPSD	COSMIC	5.604	Gain
CAMK_CAMKL_CHK1_CHEK1_ST	Q9UQ35	SRRM2	O14757	CHEK1	S2209	P2214L	2214	Missense	distal	5	no	10.101	9.939	EPSD	COSMIC	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q9UQ35	SRRM2	O14757	CHEK1	S2209	A2202V	2202	Missense	distal	-7	no	10.101	9.444	EPSD	COSMIC;GDSC;CCLE	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q9UQ35	SRRM2	O14757	CHEK1	S2219	P2214L	2214	Missense	distal	-5	no	2.929	7.636	EPSD	COSMIC	5.604	Gain
CAMK_CAMKL_CHK1_CHEK1_ST	Q9UQ35	SRRM2	O14757	CHEK1	T2261	A2267V	2267	Missense	distal	6	no	5.910	5.798	EPSD	COSMIC	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q9UQ35	SRRM2	O14757	CHEK1	T2261	A2257S	2257	Missense	distal	-4	no	5.910	5.531	EPSD	COSMIC	5.604	Loss
CAMK_CAMKL_CHK1_CHEK1_ST	Q9UQ35	SRRM2	O14757	CHEK1	T2261	S2259C	2259	Missense	proximal	-2	no	5.910	5.958	EPSD	COSMIC	5.604	Up-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q9UQ35	SRRM2	O14757	CHEK1	T2291	P2293S	2293	Missense	proximal	2	no	8.619	8.695	EPSD	COSMIC	5.604	Up-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q9UQ35	SRRM2	O14757	CHEK1	T2291	P2290S	2290	Missense	proximal	-1	no	8.619	8.172	EPSD	COSMIC;GDSC;CCLE	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q9UQ35	SRRM2	O14757	CHEK1	T2291	D2286N	2286	Missense	distal	-5	no	8.619	9.887	EPSD	COSMIC	5.604	Up-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q9UQ35	SRRM2	O14757	CHEK1	S2382	N2379K	2379	Missense	distal	-3	no	-0.909	5.634	EPSD	COSMIC	5.604	Gain
CAMK_CAMKL_CHK1_CHEK1_ST	Q9UQ35	SRRM2	O14757	CHEK1	S2407	D2403H	2403	Missense	distal	-4	no	13.696	13.436	EPSD	COSMIC	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q9UQ35	SRRM2	O14757	CHEK1	S2407	P2400L	2400	Missense	distal	-7	no	13.696	13.482	EPSD	COSMIC	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q9UQ35	SRRM2	O14757	CHEK1	T2409	D2403H	2403	Missense	distal	-6	no	6.681	6.883	EPSD	COSMIC	5.604	Up-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q9UQ35	SRRM2	O14757	CHEK1	S2421	R2423W	2423	Missense	proximal	2	no	7.443	7.268	EPSD	COSMIC	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q9UQ35	SRRM2	O14757	CHEK1	S2426	R2423W	2423	Missense	distal	-3	no	9.019	-24.584	EPSD	COSMIC	5.604	Loss
CAMK_CAMKL_CHK1_CHEK1_ST	Q9UQ35	SRRM2	O14757	CHEK1	S2533	S2539F	2539	Missense	distal	6	no	7.570	7.973	EPSD	COSMIC	5.604	Up-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q9UQ35	SRRM2	O14757	CHEK1	S2581	T2583P	2583	Missense	proximal	2	no	10.877	11.192	EPSD	COSMIC	5.604	Up-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q9UQ35	SRRM2	O14757	CHEK1	S2581	K2577M	2577	Missense	distal	-4	no	10.877	10.612	EPSD	COSMIC	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q9UQ35	SRRM2	O14757	CHEK1	S2677	R2676H	2676	Missense	proximal	-1	no	6.507	6.632	EPSD	COSMIC	5.604	Up-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q9UQ35	SRRM2	O14757	CHEK1	S2677	S2684F	2684	Missense	distal	7	no	6.507	6.077	EPSD	COSMIC	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q9UQ35	SRRM2	O14757	CHEK1	S2677	R2673W	2673	Missense	distal	-4	no	6.507	5.745	EPSD	COSMIC	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q9UQ35	SRRM2	O14757	CHEK1	S2692	Y2693C	2693	Missense	proximal	1	no	6.488	6.521	EPSD	COSMIC	5.604	Up-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q9UQ35	SRRM2	O14757	CHEK1	S2692	R2699C	2699	Missense	distal	7	no	6.488	6.082	EPSD	COSMIC;GDSC;CCLE	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q9UQ35	SRRM2	O14757	CHEK1	S2702	R2699C	2699	Missense	distal	-3	no	8.080	-0.012	EPSD	COSMIC;GDSC;CCLE	5.604	Loss
CAMK_CAMKL_CHK1_CHEK1_ST	Q9UQ35	SRRM2	O14757	CHEK1	S2727	R2721T	2721	Missense	distal	-6	no	8.884	9.033	EPSD	COSMIC	5.604	Up-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q9UQ35	SRRM2	O14757	CHEK1	T2738	P2739S	2739	Missense	proximal	1	no	8.671	8.707	EPSD	COSMIC	5.604	Up-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q9UQ35	SRRM2	O14757	CHEK1	S2748	R2747C	2747	Missense	proximal	-1	no	5.978	6.013	EPSD	COSMIC	5.604	Up-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q9P2D1	CHD7	O14757	CHEK1	S417	P421L	421	Missense	distal	4	no	9.414	9.311	EPSD	COSMIC	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q9P2D1	CHD7	O14757	CHEK1	T689	A685E	685	Missense	distal	-4	no	7.870	8.002	EPSD	COSMIC	5.604	Up-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q9P2D1	CHD7	O14757	CHEK1	T689	E682K	682	Missense	distal	-7	no	7.870	8.567	EPSD	COSMIC	5.604	Up-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q9P2D1	CHD7	O14757	CHEK1	T689	T689M	689	Missense	central	0	yes	7.870	0.000	EPSD	COSMIC	5.604	Loss
CAMK_CAMKL_CHK1_CHEK1_ST	Q9P2D1	CHD7	O14757	CHEK1	T1227	L1229F	1229	Missense	proximal	2	no	6.721	6.971	PhosphoSitePlus	COSMIC	5.604	Up-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q9P2D1	CHD7	O14757	CHEK1	T1227	L1229V	1229	Missense	proximal	2	no	6.721	7.009	PhosphoSitePlus	COSMIC	5.604	Up-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q9P2D1	CHD7	O14757	CHEK1	T1227	S1230F	1230	Missense	distal	3	no	6.721	6.909	PhosphoSitePlus	COSMIC	5.604	Up-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q9P2D1	CHD7	O14757	CHEK1	T1635	R1629H	1629	Missense	distal	-6	no	9.656	9.765	EPSD	COSMIC	5.604	Up-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q9P2D1	CHD7	O14757	CHEK1	T1635	R1632C	1632	Missense	distal	-3	no	9.656	1.564	EPSD	COSMIC;CCLE	5.604	Loss
CAMK_CAMKL_CHK1_CHEK1_ST	Q9P2D1	CHD7	O14757	CHEK1	T1635	G1628R	1628	Missense	distal	-7	no	9.656	9.617	EPSD	COSMIC	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q9P2D1	CHD7	O14757	CHEK1	S2533	H2529Q	2529	Missense	distal	-4	no	5.504	5.862	EPSD	COSMIC	5.604	Gain
CAMK_CAMKL_CHK1_CHEK1_ST	Q13439	GOLGA4	O14757	CHEK1	S10	K8T	8	Missense	proximal	-2	no	6.808	7.144	EPSD	COSMIC	5.604	Up-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q13439	GOLGA4	O14757	CHEK1	S37	E44Q	44	Missense	distal	7	no	8.135	8.050	EPSD	COSMIC	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q13439	GOLGA4	O14757	CHEK1	T39	E44Q	44	Missense	distal	5	no	8.217	8.104	EPSD	COSMIC	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q13439	GOLGA4	O14757	CHEK1	S41	E44Q	44	Missense	distal	3	no	6.884	6.484	EPSD	COSMIC	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q13439	GOLGA4	O14757	CHEK1	S71	R68W	68	Missense	distal	-3	no	7.854	-25.749	PhosphoSitePlus	COSMIC;GDSC	5.604	Loss
CAMK_CAMKL_CHK1_CHEK1_ST	Q13439	GOLGA4	O14757	CHEK1	S71	S71F	71	Missense	central	0	yes	7.854	0.000	PhosphoSitePlus	COSMIC	5.604	Loss
CAMK_CAMKL_CHK1_CHEK1_ST	Q13439	GOLGA4	O14757	CHEK1	S71	R68Q	68	Missense	distal	-3	no	7.854	0.648	PhosphoSitePlus	COSMIC	5.604	Loss
CAMK_CAMKL_CHK1_CHEK1_ST	Q13439	GOLGA4	O14757	CHEK1	S98	S98Y	98	Missense	central	0	yes	13.469	0.000	EPSD	COSMIC;GDSC	5.604	Loss
CAMK_CAMKL_CHK1_CHEK1_ST	Q13439	GOLGA4	O14757	CHEK1	S98	S97Y	97	Missense	proximal	-1	no	13.469	13.798	EPSD	COSMIC	5.604	Up-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q13439	GOLGA4	O14757	CHEK1	S151	R148Q	148	Missense	distal	-3	no	7.434	0.227	EPSD	COSMIC	5.604	Loss
CAMK_CAMKL_CHK1_CHEK1_ST	Q13439	GOLGA4	O14757	CHEK1	S179	Q175H	175	Missense	distal	-4	no	6.395	6.038	EPSD	COSMIC	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q13439	GOLGA4	O14757	CHEK1	S1124	N1123T	1123	Missense	proximal	-1	no	5.763	5.749	EPSD	COSMIC	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q13439	GOLGA4	O14757	CHEK1	S1124	S1124F	1124	Missense	central	0	yes	5.763	0.000	EPSD	COSMIC	5.604	Loss
CAMK_CAMKL_CHK1_CHEK1_ST	Q13439	GOLGA4	O14757	CHEK1	S1124	S1119F	1119	Missense	distal	-5	no	5.763	5.388	EPSD	COSMIC	5.604	Loss
CAMK_CAMKL_CHK1_CHEK1_ST	Q13439	GOLGA4	O14757	CHEK1	T1746	R1743I	1743	Missense	distal	-3	no	15.138	6.380	EPSD	COSMIC;GDSC;CCLE	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q13439	GOLGA4	O14757	CHEK1	S1809	K1806N	1806	Missense	distal	-3	no	7.128	0.585	EPSD	COSMIC;GDSC;CCLE	5.604	Loss
CAMK_CAMKL_CHK1_CHEK1_ST	Q13439	GOLGA4	O14757	CHEK1	S1809	S1809F	1809	Missense	central	0	yes	7.128	0.000	EPSD	COSMIC	5.604	Loss
CAMK_CAMKL_CHK1_CHEK1_ST	Q13439	GOLGA4	O14757	CHEK1	S1809	I1811M	1811	Missense	proximal	2	no	7.128	7.708	EPSD	COSMIC	5.604	Up-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q13439	GOLGA4	O14757	CHEK1	S1861	Q1854K	1854	Missense	distal	-7	no	4.787	5.709	EPSD	COSMIC	5.604	Gain
CAMK_CAMKL_CHK1_CHEK1_ST	Q9UEY8	ADD3	O14757	CHEK1	S42	P43S	43	Missense	proximal	1	no	7.170	7.206	EPSD	COSMIC	5.604	Up-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q9UEY8	ADD3	O14757	CHEK1	S180	R177K	177	Missense	distal	-3	no	10.811	6.985	EPSD	COSMIC	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q9UEY8	ADD3	O14757	CHEK1	S402	P407L	407	Missense	distal	5	no	12.112	11.950	EPSD	COSMIC;CCLE	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q9UEY8	ADD3	O14757	CHEK1	S402	E405K	405	Missense	distal	3	no	12.112	11.296	EPSD	COSMIC	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q9UEY8	ADD3	O14757	CHEK1	S461	G458R	458	Missense	distal	-3	no	2.223	9.998	EPSD	COSMIC;CCLE	5.604	Gain
CAMK_CAMKL_CHK1_CHEK1_ST	Q9UEY8	ADD3	O14757	CHEK1	S693	R690H	690	Missense	distal	-3	no	8.097	2.288	PhosphoSitePlus	COSMIC;GDSC;CCLE	5.604	Loss
CAMK_CAMKL_CHK1_CHEK1_ST	Q9UEY8	ADD3	O14757	CHEK1	S693	N698K	698	Missense	distal	5	no	8.097	8.119	PhosphoSitePlus	COSMIC	5.604	Up-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q9UEY8	ADD3	O14757	CHEK1	S693	F689V	689	Missense	distal	-4	no	8.097	8.639	PhosphoSitePlus	COSMIC	5.604	Up-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q9BW19	KIFC1	O14757	CHEK1	S71	H66R	66	Missense	distal	-5	no	5.969	8.434	EPSD	COSMIC	5.604	Up-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q9BW19	KIFC1	O14757	CHEK1	S71	S65F	65	Missense	distal	-6	no	5.969	6.243	EPSD	COSMIC	5.604	Up-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q9BW19	KIFC1	O14757	CHEK1	S71	S71F	71	Missense	central	0	yes	5.969	0.000	EPSD	COSMIC	5.604	Loss
CAMK_CAMKL_CHK1_CHEK1_ST	Q9BW19	KIFC1	O14757	CHEK1	T359	E355K	355	Missense	distal	-4	no	7.057	6.955	EPSD	COSMIC	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q9BW19	KIFC1	O14757	CHEK1	S373	R376Q	376	Missense	distal	3	no	4.752	5.814	EPSD	COSMIC	5.604	Gain
CAMK_CAMKL_CHK1_CHEK1_ST	Q9BW19	KIFC1	O14757	CHEK1	S648	E644G	644	Missense	distal	-4	no	6.706	6.529	EPSD	COSMIC;GDSC	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q9BW19	KIFC1	O14757	CHEK1	S648	S648F	648	Missense	central	0	yes	6.706	0.000	EPSD	COSMIC	5.604	Loss
CAMK_CAMKL_CHK1_CHEK1_ST	Q9BW19	KIFC1	O14757	CHEK1	S648	R655L	655	Missense	distal	7	no	6.706	6.606	EPSD	COSMIC	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	P43243	MATR3	O14757	CHEK1	S22	G25R	25	Missense	distal	3	no	6.427	6.512	EPSD	COSMIC	5.604	Up-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	P43243	MATR3	O14757	CHEK1	S22	A23V	23	Missense	proximal	1	no	6.427	6.403	EPSD	COSMIC	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	P43243	MATR3	O14757	CHEK1	S22	G25V	25	Missense	distal	3	no	6.427	6.853	EPSD	COSMIC	5.604	Up-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	P43243	MATR3	O14757	CHEK1	S22	G16C	16	Missense	distal	-6	no	6.427	6.425	EPSD	COSMIC	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	P43243	MATR3	O14757	CHEK1	S41	G48E	48	Missense	distal	7	no	5.391	5.625	EPSD	COSMIC	5.604	Gain
CAMK_CAMKL_CHK1_CHEK1_ST	P43243	MATR3	O14757	CHEK1	S54	A53E	53	Missense	proximal	-1	no	12.242	11.979	EPSD	COSMIC	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	P43243	MATR3	O14757	CHEK1	S54	G48E	48	Missense	distal	-6	no	12.242	12.082	EPSD	COSMIC	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	P43243	MATR3	O14757	CHEK1	T150	L156I	156	Missense	distal	6	no	10.156	9.789	EPSD;PhosphoSitePlus	COSMIC	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	P43243	MATR3	O14757	CHEK1	T166	G162C	162	Missense	distal	-4	no	6.691	6.291	EPSD	COSMIC	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	P43243	MATR3	O14757	CHEK1	T166	P170Q	170	Missense	distal	4	no	6.691	6.601	EPSD	COSMIC	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	P43243	MATR3	O14757	CHEK1	S188	S195T	195	Missense	distal	7	no	9.262	9.195	EPSD	COSMIC	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	P43243	MATR3	O14757	CHEK1	S195	N197T	197	Missense	proximal	2	no	10.722	10.149	PhosphoSitePlus;EPSD	COSMIC	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	P43243	MATR3	O14757	CHEK1	S195	D201H	201	Missense	distal	6	no	10.722	11.282	PhosphoSitePlus;EPSD	COSMIC	5.604	Up-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	P43243	MATR3	O14757	CHEK1	S234	S234F	234	Missense	central	0	yes	6.706	0.000	EPSD	COSMIC	5.604	Loss
CAMK_CAMKL_CHK1_CHEK1_ST	P43243	MATR3	O14757	CHEK1	S248	D247N	247	Missense	proximal	-1	no	6.962	7.050	EPSD	COSMIC	5.604	Up-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	P43243	MATR3	O14757	CHEK1	S248	R255Q	255	Missense	distal	7	no	6.962	7.116	EPSD	COSMIC	5.604	Up-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	P43243	MATR3	O14757	CHEK1	S307	N303H	303	Missense	distal	-4	no	6.619	6.435	EPSD	COSMIC	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	P43243	MATR3	O14757	CHEK1	T396	G392D	392	Missense	distal	-4	no	7.798	7.834	EPSD	COSMIC;CCLE	5.604	Up-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	P43243	MATR3	O14757	CHEK1	S533	I537V	537	Missense	distal	4	no	11.499	11.559	EPSD	COSMIC	5.604	Up-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	P43243	MATR3	O14757	CHEK1	S592	R593Q	593	Missense	proximal	1	no	6.533	6.542	EPSD	COSMIC	5.604	Up-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	P43243	MATR3	O14757	CHEK1	S596	R593Q	593	Missense	distal	-3	no	10.374	3.167	EPSD	COSMIC	5.604	Loss
CAMK_CAMKL_CHK1_CHEK1_ST	P43243	MATR3	O14757	CHEK1	S598	R593Q	593	Missense	distal	-5	no	8.638	8.242	EPSD	COSMIC	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	P33992	MCM5	O14757	CHEK1	S423	V418G	418	Missense	distal	-5	no	11.644	11.979	EPSD	COSMIC	5.604	Up-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	P33992	MCM5	O14757	CHEK1	S423	R425Q	425	Missense	proximal	2	no	11.644	12.173	EPSD	COSMIC	5.604	Up-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	P33992	MCM5	O14757	CHEK1	S423	S423L	423	Missense	central	0	yes	11.644	0.000	EPSD	COSMIC	5.604	Loss
CAMK_CAMKL_CHK1_CHEK1_ST	P33992	MCM5	O14757	CHEK1	S423	I428V	428	Missense	distal	5	no	11.644	11.702	EPSD	COSMIC	5.604	Up-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	P33992	MCM5	O14757	CHEK1	S605	D601G	601	Missense	distal	-4	no	9.322	9.286	EPSD	COSMIC;GDSC;CCLE	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	P33992	MCM5	O14757	CHEK1	S605	D601N	601	Missense	distal	-4	no	9.322	9.246	EPSD	COSMIC	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	P33992	MCM5	O14757	CHEK1	T633	A640D	640	Missense	distal	7	no	5.688	6.030	PhosphoSitePlus	COSMIC	5.604	Up-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	P33992	MCM5	O14757	CHEK1	T633	A640V	640	Missense	distal	7	no	5.688	5.768	PhosphoSitePlus	COSMIC	5.604	Up-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q96T58	SPEN	O14757	CHEK1	S43	A48T	48	Missense	distal	5	no	10.511	10.270	EPSD	COSMIC	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q96T58	SPEN	O14757	CHEK1	S43	G45V	45	Missense	proximal	2	no	10.511	10.470	EPSD	COSMIC	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q96T58	SPEN	O14757	CHEK1	S43	R41S	41	Missense	proximal	-2	no	10.511	10.412	EPSD	COSMIC	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q96T58	SPEN	O14757	CHEK1	S43	P39L	39	Missense	distal	-4	no	10.511	10.327	EPSD	COSMIC	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q96T58	SPEN	O14757	CHEK1	S190	H197Y	197	Missense	distal	7	no	6.239	5.925	EPSD	COSMIC;GDSC;CCLE	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q96T58	SPEN	O14757	CHEK1	S190	R189Q	189	Missense	proximal	-1	no	6.239	6.255	EPSD	COSMIC;GDSC;CCLE	5.604	Up-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q96T58	SPEN	O14757	CHEK1	S190	P191Q	191	Missense	proximal	1	no	6.239	6.311	EPSD	COSMIC	5.604	Up-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q96T58	SPEN	O14757	CHEK1	S190	R193H	193	Missense	distal	3	no	6.239	6.270	EPSD	COSMIC	5.604	Up-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q96T58	SPEN	O14757	CHEK1	S190	R187W	187	Missense	distal	-3	no	6.239	-27.364	EPSD	COSMIC	5.604	Loss
CAMK_CAMKL_CHK1_CHEK1_ST	Q96T58	SPEN	O14757	CHEK1	S190	P191L	191	Missense	proximal	1	no	6.239	6.267	EPSD	COSMIC	5.604	Up-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q96T58	SPEN	O14757	CHEK1	S244	S250C	250	Missense	distal	6	no	6.042	6.424	EPSD	COSMIC	5.604	Up-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q96T58	SPEN	O14757	CHEK1	S244	R243Q	243	Missense	proximal	-1	no	6.042	6.058	EPSD	COSMIC;GDSC;CCLE	5.604	Up-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q96T58	SPEN	O14757	CHEK1	S244	S248P	248	Missense	distal	4	no	6.042	6.182	EPSD	COSMIC	5.604	Up-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q96T58	SPEN	O14757	CHEK1	S260	A262S	262	Missense	proximal	2	no	8.135	7.679	EPSD	COSMIC	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q96T58	SPEN	O14757	CHEK1	S260	P265T	265	Missense	distal	5	no	8.135	7.995	EPSD	COSMIC	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q96T58	SPEN	O14757	CHEK1	S260	Q256E	256	Missense	distal	-4	no	8.135	8.179	EPSD	COSMIC;CCLE	5.604	Up-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q96T58	SPEN	O14757	CHEK1	S270	P265T	265	Missense	distal	-5	no	5.461	8.112	EPSD	COSMIC	5.604	Gain
CAMK_CAMKL_CHK1_CHEK1_ST	Q96T58	SPEN	O14757	CHEK1	S270	S268F	268	Missense	proximal	-2	no	5.461	5.751	EPSD	COSMIC;GDSC;CCLE	5.604	Gain
CAMK_CAMKL_CHK1_CHEK1_ST	Q96T58	SPEN	O14757	CHEK1	S278	G271S	271	Missense	distal	-7	no	7.149	7.370	EPSD	COSMIC	5.604	Up-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q96T58	SPEN	O14757	CHEK1	T534	S529L	529	Missense	distal	-5	no	2.558	5.746	EPSD	COSMIC	5.604	Gain
CAMK_CAMKL_CHK1_CHEK1_ST	Q96T58	SPEN	O14757	CHEK1	S623	D625N	625	Missense	proximal	2	no	7.308	7.024	EPSD	COSMIC	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q96T58	SPEN	O14757	CHEK1	S623	Y624C	624	Missense	proximal	1	no	7.308	7.342	EPSD	COSMIC	5.604	Up-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q96T58	SPEN	O14757	CHEK1	S623	E619K	619	Missense	distal	-4	no	7.308	7.206	EPSD	COSMIC	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q96T58	SPEN	O14757	CHEK1	T638	S635R	635	Missense	distal	-3	no	-1.923	7.773	EPSD	COSMIC	5.604	Gain
CAMK_CAMKL_CHK1_CHEK1_ST	Q96T58	SPEN	O14757	CHEK1	S646	Y650C	650	Missense	distal	4	no	6.338	6.318	EPSD	COSMIC	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q96T58	SPEN	O14757	CHEK1	S646	T641A	641	Missense	distal	-5	no	6.338	2.477	EPSD	COSMIC	5.604	Loss
CAMK_CAMKL_CHK1_CHEK1_ST	Q96T58	SPEN	O14757	CHEK1	S696	R700K	700	Missense	distal	4	no	11.234	11.136	EPSD	COSMIC	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q96T58	SPEN	O14757	CHEK1	S696	R693K	693	Missense	distal	-3	no	11.234	7.409	EPSD	COSMIC	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q96T58	SPEN	O14757	CHEK1	S696	Y695C	695	Missense	proximal	-1	no	11.234	11.101	EPSD	COSMIC	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q96T58	SPEN	O14757	CHEK1	S696	R693M	693	Missense	distal	-3	no	11.234	6.086	EPSD	COSMIC	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q96T58	SPEN	O14757	CHEK1	S727	S727N	727	Missense	central	0	yes	8.901	0.000	EPSD	COSMIC	5.604	Loss
CAMK_CAMKL_CHK1_CHEK1_ST	Q96T58	SPEN	O14757	CHEK1	S727	S725R	725	Missense	proximal	-2	no	8.901	9.000	EPSD	COSMIC	5.604	Up-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q96T58	SPEN	O14757	CHEK1	S727	P728L	728	Missense	proximal	1	no	8.901	8.929	EPSD	COSMIC	5.604	Up-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q96T58	SPEN	O14757	CHEK1	S736	S742F	742	Missense	distal	6	no	13.238	13.641	EPSD	COSMIC	5.604	Up-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q96T58	SPEN	O14757	CHEK1	S736	G738E	738	Missense	proximal	2	no	13.238	13.852	EPSD	COSMIC	5.604	Up-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q96T58	SPEN	O14757	CHEK1	S736	P737S	737	Missense	proximal	1	no	13.238	13.275	EPSD	COSMIC	5.604	Up-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q96T58	SPEN	O14757	CHEK1	S736	Q743E	743	Missense	distal	7	no	13.238	13.324	EPSD	COSMIC	5.604	Up-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q96T58	SPEN	O14757	CHEK1	S749	S742F	742	Missense	distal	-7	no	7.076	5.344	EPSD	COSMIC	5.604	Loss
CAMK_CAMKL_CHK1_CHEK1_ST	Q96T58	SPEN	O14757	CHEK1	S749	A744V	744	Missense	distal	-5	no	7.076	9.516	EPSD	COSMIC	5.604	Up-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q96T58	SPEN	O14757	CHEK1	S749	Q743E	743	Missense	distal	-6	no	7.076	6.952	EPSD	COSMIC	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q96T58	SPEN	O14757	CHEK1	S749	S751F	751	Missense	proximal	2	no	7.076	6.932	EPSD	COSMIC	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q96T58	SPEN	O14757	CHEK1	S749	R746S	746	Missense	distal	-3	no	7.076	-2.620	EPSD	COSMIC	5.604	Loss
CAMK_CAMKL_CHK1_CHEK1_ST	Q96T58	SPEN	O14757	CHEK1	S757	D761E	761	Missense	distal	4	no	6.656	6.564	EPSD	COSMIC	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q96T58	SPEN	O14757	CHEK1	S757	S751F	751	Missense	distal	-6	no	6.656	6.929	EPSD	COSMIC	5.604	Up-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q96T58	SPEN	O14757	CHEK1	S765	S770F	770	Missense	distal	5	no	8.886	8.561	EPSD	COSMIC	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q96T58	SPEN	O14757	CHEK1	S765	D761E	761	Missense	distal	-4	no	8.886	9.028	EPSD	COSMIC	5.604	Up-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q96T58	SPEN	O14757	CHEK1	S765	P771S	771	Missense	distal	6	no	8.886	8.267	EPSD	COSMIC	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q96T58	SPEN	O14757	CHEK1	S830	K825N	825	Missense	distal	-5	no	6.492	5.598	EPSD	COSMIC	5.604	Loss
CAMK_CAMKL_CHK1_CHEK1_ST	Q96T58	SPEN	O14757	CHEK1	S830	S832G	832	Missense	proximal	2	no	6.492	6.427	EPSD	COSMIC	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q96T58	SPEN	O14757	CHEK1	S830	S835F	835	Missense	distal	5	no	6.492	6.167	EPSD	COSMIC	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q96T58	SPEN	O14757	CHEK1	S830	R824P	824	Missense	distal	-6	no	6.492	6.669	EPSD	COSMIC	5.604	Up-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q96T58	SPEN	O14757	CHEK1	S832	K825N	825	Missense	distal	-7	no	6.015	4.557	EPSD	COSMIC	5.604	Loss
CAMK_CAMKL_CHK1_CHEK1_ST	Q96T58	SPEN	O14757	CHEK1	S832	S832G	832	Missense	central	0	yes	6.015	0.000	EPSD	COSMIC	5.604	Loss
CAMK_CAMKL_CHK1_CHEK1_ST	Q96T58	SPEN	O14757	CHEK1	S832	T838R	838	Missense	distal	6	no	6.015	5.792	EPSD	COSMIC	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q96T58	SPEN	O14757	CHEK1	S832	S835F	835	Missense	distal	3	no	6.015	6.203	EPSD	COSMIC	5.604	Up-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q96T58	SPEN	O14757	CHEK1	S847	R844Q	844	Missense	distal	-3	no	11.313	4.106	EPSD	COSMIC	5.604	Loss
CAMK_CAMKL_CHK1_CHEK1_ST	Q96T58	SPEN	O14757	CHEK1	S847	P851L	851	Missense	distal	4	no	11.313	11.209	EPSD	COSMIC	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q96T58	SPEN	O14757	CHEK1	S847	S853N	853	Missense	distal	6	no	11.313	11.447	EPSD	COSMIC	5.604	Up-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q96T58	SPEN	O14757	CHEK1	S946	S946L	946	Missense	central	0	yes	6.815	0.000	EPSD	COSMIC	5.604	Loss
CAMK_CAMKL_CHK1_CHEK1_ST	Q96T58	SPEN	O14757	CHEK1	S946	K943R	943	Missense	distal	-3	no	6.815	10.641	EPSD	COSMIC	5.604	Up-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q96T58	SPEN	O14757	CHEK1	S946	V951M	951	Missense	distal	5	no	6.815	6.788	EPSD	COSMIC	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q96T58	SPEN	O14757	CHEK1	T1059	C1066G	1066	Missense	distal	7	no	12.296	12.707	PhosphoSitePlus	COSMIC	5.604	Up-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q96T58	SPEN	O14757	CHEK1	T1059	K1064N	1064	Missense	distal	5	no	12.296	12.273	PhosphoSitePlus	COSMIC	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q96T58	SPEN	O14757	CHEK1	T1059	A1061G	1061	Missense	proximal	2	no	12.296	11.774	PhosphoSitePlus	COSMIC	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q96T58	SPEN	O14757	CHEK1	T1059	K1064E	1064	Missense	distal	5	no	12.296	12.361	PhosphoSitePlus	COSMIC;GDSC;CCLE	5.604	Up-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q96T58	SPEN	O14757	CHEK1	S1082	S1082L	1082	Missense	central	0	yes	8.936	0.000	EPSD	COSMIC;GDSC;CCLE	5.604	Loss
CAMK_CAMKL_CHK1_CHEK1_ST	Q96T58	SPEN	O14757	CHEK1	S1194	K1197T	1197	Missense	distal	3	no	7.605	6.818	EPSD	COSMIC	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q96T58	SPEN	O14757	CHEK1	S1194	D1198N	1198	Missense	distal	4	no	7.605	7.574	EPSD	COSMIC	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q96T58	SPEN	O14757	CHEK1	S1252	D1254N	1254	Missense	proximal	2	no	9.043	8.758	EPSD	COSMIC;GDSC;CCLE	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q96T58	SPEN	O14757	CHEK1	S1252	G1259S	1259	Missense	distal	7	no	9.043	8.944	EPSD	COSMIC	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q96T58	SPEN	O14757	CHEK1	S1252	E1253K	1253	Missense	proximal	1	no	9.043	8.969	EPSD	COSMIC	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q96T58	SPEN	O14757	CHEK1	S1252	Q1250H	1250	Missense	proximal	-2	no	9.043	9.061	EPSD	COSMIC	5.604	Up-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q96T58	SPEN	O14757	CHEK1	S1252	S1255F	1255	Missense	distal	3	no	9.043	9.231	EPSD	COSMIC	5.604	Up-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q96T58	SPEN	O14757	CHEK1	S1268	D1274Y	1274	Missense	distal	6	no	9.381	10.306	EPSD	COSMIC	5.604	Up-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q96T58	SPEN	O14757	CHEK1	S1268	E1271A	1271	Missense	distal	3	no	9.381	8.015	EPSD	COSMIC;GDSC	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q96T58	SPEN	O14757	CHEK1	S1268	E1271G	1271	Missense	distal	3	no	9.381	7.833	EPSD	COSMIC	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q96T58	SPEN	O14757	CHEK1	S1268	H1270Y	1270	Missense	proximal	2	no	9.381	9.161	EPSD	COSMIC	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q96T58	SPEN	O14757	CHEK1	S1306	Y1312F	1312	Missense	distal	6	no	7.820	7.481	EPSD	COSMIC	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q96T58	SPEN	O14757	CHEK1	S1369	G1376D	1376	Missense	distal	7	no	9.734	10.026	EPSD	COSMIC	5.604	Up-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q96T58	SPEN	O14757	CHEK1	S1424	L1426V	1426	Missense	proximal	2	no	9.156	9.444	EPSD	COSMIC	5.604	Up-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q96T58	SPEN	O14757	CHEK1	T1441	T1444S	1444	Missense	distal	3	no	5.510	5.654	EPSD	COSMIC	5.604	Gain
CAMK_CAMKL_CHK1_CHEK1_ST	Q96T58	SPEN	O14757	CHEK1	S1453	S1455P	1455	Missense	proximal	2	no	13.331	13.255	EPSD	COSMIC	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q96T58	SPEN	O14757	CHEK1	S1453	S1455F	1455	Missense	proximal	2	no	13.331	13.187	EPSD	COSMIC	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q96T58	SPEN	O14757	CHEK1	S1453	S1455A	1455	Missense	proximal	2	no	13.331	13.788	EPSD	COSMIC	5.604	Up-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q96T58	SPEN	O14757	CHEK1	S1453	R1458L	1458	Missense	distal	5	no	13.331	13.191	EPSD	COSMIC	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q96T58	SPEN	O14757	CHEK1	S1485	D1484V	1484	Missense	proximal	-1	no	9.113	9.239	EPSD	COSMIC	5.604	Up-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q96T58	SPEN	O14757	CHEK1	S1485	E1481K	1481	Missense	distal	-4	no	9.113	9.011	EPSD	COSMIC	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q96T58	SPEN	O14757	CHEK1	S1485	V1483I	1483	Missense	proximal	-2	no	9.113	9.050	EPSD	COSMIC	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q96T58	SPEN	O14757	CHEK1	T1502	K1496Q	1496	Missense	distal	-6	no	7.571	7.664	EPSD	COSMIC	5.604	Up-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q96T58	SPEN	O14757	CHEK1	T1502	M1495T	1495	Missense	distal	-7	no	7.571	7.105	EPSD	COSMIC	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q96T58	SPEN	O14757	CHEK1	T1502	G1506W	1506	Missense	distal	4	no	7.571	7.618	EPSD	COSMIC	5.604	Up-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q96T58	SPEN	O14757	CHEK1	S1504	G1506W	1506	Missense	proximal	2	no	13.048	12.843	EPSD	COSMIC	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q96T58	SPEN	O14757	CHEK1	S1566	S1566F	1566	Missense	central	0	yes	5.651	0.000	EPSD	COSMIC	5.604	Loss
CAMK_CAMKL_CHK1_CHEK1_ST	Q96T58	SPEN	O14757	CHEK1	S1566	R1559S	1559	Missense	distal	-7	no	5.651	5.910	EPSD	COSMIC	5.604	Up-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q96T58	SPEN	O14757	CHEK1	S1566	T1573I	1573	Missense	distal	7	no	5.651	5.425	EPSD	COSMIC	5.604	Loss
CAMK_CAMKL_CHK1_CHEK1_ST	Q96T58	SPEN	O14757	CHEK1	S1566	E1567K	1567	Missense	proximal	1	no	5.651	5.577	EPSD	COSMIC	5.604	Loss
CAMK_CAMKL_CHK1_CHEK1_ST	Q96T58	SPEN	O14757	CHEK1	S1566	E1567Q	1567	Missense	proximal	1	no	5.651	5.585	EPSD	COSMIC;CCLE	5.604	Loss
CAMK_CAMKL_CHK1_CHEK1_ST	Q96T58	SPEN	O14757	CHEK1	T1826	R1823C	1823	Missense	distal	-3	no	7.038	-1.053	EPSD	COSMIC	5.604	Loss
CAMK_CAMKL_CHK1_CHEK1_ST	Q96T58	SPEN	O14757	CHEK1	T1826	A1830S	1830	Missense	distal	4	no	7.038	6.845	EPSD	COSMIC	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q96T58	SPEN	O14757	CHEK1	T1826	R1823S	1823	Missense	distal	-3	no	7.038	-2.658	EPSD	COSMIC	5.604	Loss
CAMK_CAMKL_CHK1_CHEK1_ST	Q96T58	SPEN	O14757	CHEK1	S1857	N1856S	1856	Missense	proximal	-1	no	11.825	11.606	EPSD	COSMIC	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q96T58	SPEN	O14757	CHEK1	S1857	R1859W	1859	Missense	proximal	2	no	11.825	11.650	EPSD	COSMIC;GDSC;CCLE	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q96T58	SPEN	O14757	CHEK1	S1857	P1858L	1858	Missense	proximal	1	no	11.825	11.852	EPSD	COSMIC	5.604	Up-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q96T58	SPEN	O14757	CHEK1	S1857	R1854Q	1854	Missense	distal	-3	no	11.825	4.618	EPSD	COSMIC	5.604	Loss
CAMK_CAMKL_CHK1_CHEK1_ST	Q96T58	SPEN	O14757	CHEK1	S1857	N1856T	1856	Missense	proximal	-1	no	11.825	11.811	EPSD	COSMIC	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q96T58	SPEN	O14757	CHEK1	T1930	E1925K	1925	Missense	distal	-5	no	3.049	5.611	EPSD	COSMIC	5.604	Gain
CAMK_CAMKL_CHK1_CHEK1_ST	Q96T58	SPEN	O14757	CHEK1	S2305	S2311T	2311	Missense	distal	6	no	6.146	6.457	EPSD	COSMIC	5.604	Up-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q96T58	SPEN	O14757	CHEK1	S2305	S2311A	2311	Missense	distal	6	no	6.146	6.535	EPSD	COSMIC	5.604	Up-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q96T58	SPEN	O14757	CHEK1	S2305	S2311L	2311	Missense	distal	6	no	6.146	6.556	EPSD	COSMIC	5.604	Up-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q96T58	SPEN	O14757	CHEK1	S2305	R2302I	2302	Missense	distal	-3	no	6.146	-2.612	EPSD	COSMIC	5.604	Loss
CAMK_CAMKL_CHK1_CHEK1_ST	Q96T58	SPEN	O14757	CHEK1	S2392	S2392F	2392	Missense	central	0	yes	8.135	0.000	EPSD	COSMIC	5.604	Loss
CAMK_CAMKL_CHK1_CHEK1_ST	Q96T58	SPEN	O14757	CHEK1	S2392	Q2396E	2396	Missense	distal	4	no	8.135	8.043	EPSD	COSMIC	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q96T58	SPEN	O14757	CHEK1	S2407	L2402P	2402	Missense	distal	-5	no	6.767	2.060	EPSD	COSMIC	5.604	Loss
CAMK_CAMKL_CHK1_CHEK1_ST	Q96T58	SPEN	O14757	CHEK1	S2407	S2411P	2411	Missense	distal	4	no	6.767	6.907	EPSD	COSMIC	5.604	Up-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q96T58	SPEN	O14757	CHEK1	S2407	E2409D	2409	Missense	proximal	2	no	6.767	6.684	EPSD	COSMIC	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q96T58	SPEN	O14757	CHEK1	S2407	N2410S	2410	Missense	distal	3	no	6.767	5.926	EPSD	COSMIC	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q96T58	SPEN	O14757	CHEK1	T2423	S2416C	2416	Missense	distal	-7	no	6.850	5.862	EPSD	COSMIC	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q96T58	SPEN	O14757	CHEK1	T2423	P2429S	2429	Missense	distal	6	no	6.850	6.230	EPSD	COSMIC	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q96T58	SPEN	O14757	CHEK1	T2423	E2418Q	2418	Missense	distal	-5	no	6.850	7.840	EPSD	COSMIC	5.604	Up-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q96T58	SPEN	O14757	CHEK1	S2452	S2452F	2452	Missense	central	0	yes	10.929	0.000	EPSD	COSMIC;GDSC;CCLE	5.604	Loss
CAMK_CAMKL_CHK1_CHEK1_ST	Q96T58	SPEN	O14757	CHEK1	S2860	A2863S	2863	Missense	distal	3	no	6.934	6.840	EPSD	COSMIC	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q96T58	SPEN	O14757	CHEK1	S2860	S2860F	2860	Missense	central	0	yes	6.934	0.000	EPSD	COSMIC	5.604	Loss
CAMK_CAMKL_CHK1_CHEK1_ST	Q96T58	SPEN	O14757	CHEK1	S3035	G3032R	3032	Missense	distal	-3	no	1.958	9.733	EPSD	COSMIC	5.604	Gain
CAMK_CAMKL_CHK1_CHEK1_ST	Q96T58	SPEN	O14757	CHEK1	T3102	I3108V	3108	Missense	distal	6	no	6.301	6.534	EPSD	COSMIC	5.604	Up-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q96T58	SPEN	O14757	CHEK1	T3102	E3097D	3097	Missense	distal	-5	no	6.301	6.700	EPSD	COSMIC	5.604	Up-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q96T58	SPEN	O14757	CHEK1	T3102	E3097K	3097	Missense	distal	-5	no	6.301	8.863	EPSD	COSMIC;CCLE	5.604	Up-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q96T58	SPEN	O14757	CHEK1	T3102	T3104M	3104	Missense	proximal	2	no	6.301	6.766	EPSD	COSMIC	5.604	Up-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q96T58	SPEN	O14757	CHEK1	T3139	R3136C	3136	Missense	distal	-3	no	6.682	-1.409	EPSD	COSMIC	5.604	Loss
CAMK_CAMKL_CHK1_CHEK1_ST	Q96T58	SPEN	O14757	CHEK1	T3139	P3140S	3140	Missense	proximal	1	no	6.682	6.719	EPSD	COSMIC	5.604	Up-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q96T58	SPEN	O14757	CHEK1	T3568	A3564G	3564	Missense	distal	-4	no	7.244	7.199	EPSD	COSMIC	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q96T58	SPEN	O14757	CHEK1	T3568	R3565Q	3565	Missense	distal	-3	no	7.244	0.037	EPSD	COSMIC	5.604	Loss
CAMK_CAMKL_CHK1_CHEK1_ST	Q96T58	SPEN	O14757	CHEK1	T3568	G3562R	3562	Missense	distal	-6	no	7.244	7.126	EPSD	COSMIC	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q9NRM7	LATS2	O14757	CHEK1	T5	A8V	8	Missense	distal	3	no	6.148	6.392	EPSD	COSMIC	5.604	Up-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q9NRM7	LATS2	O14757	CHEK1	T58	Q62K	62	Missense	distal	4	no	6.889	6.792	EPSD	COSMIC	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q9NRM7	LATS2	O14757	CHEK1	T58	Q61R	61	Missense	distal	3	no	6.889	5.827	EPSD	COSMIC	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q9NRM7	LATS2	O14757	CHEK1	T58	S54N	54	Missense	distal	-4	no	6.889	7.184	EPSD	COSMIC	5.604	Up-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q9NRM7	LATS2	O14757	CHEK1	T58	G53E	53	Missense	distal	-5	no	6.889	5.668	EPSD	COSMIC	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q9NRM7	LATS2	O14757	CHEK1	S172	T165A	165	Missense	distal	-7	no	6.543	7.859	EPSD	COSMIC	5.604	Up-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q9NRM7	LATS2	O14757	CHEK1	S172	R169Q	169	Missense	distal	-3	no	6.543	-0.664	EPSD	COSMIC;GDSC	5.604	Loss
CAMK_CAMKL_CHK1_CHEK1_ST	Q9NRM7	LATS2	O14757	CHEK1	S172	D178N	178	Missense	distal	6	no	6.543	6.861	EPSD	COSMIC	5.604	Up-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q9NRM7	LATS2	O14757	CHEK1	S274	R271H	271	Missense	distal	-3	no	8.401	2.591	EPSD	COSMIC;CCLE	5.604	Loss
CAMK_CAMKL_CHK1_CHEK1_ST	Q9NRM7	LATS2	O14757	CHEK1	S274	S274F	274	Missense	central	0	yes	8.401	0.000	EPSD	COSMIC	5.604	Loss
CAMK_CAMKL_CHK1_CHEK1_ST	Q9NRM7	LATS2	O14757	CHEK1	S380	S380F	380	Missense	central	0	yes	16.516	0.000	EPSD	COSMIC	5.604	Loss
CAMK_CAMKL_CHK1_CHEK1_ST	Q9NRM7	LATS2	O14757	CHEK1	S380	R378W	378	Missense	proximal	-2	no	16.516	16.638	EPSD	COSMIC	5.604	Up-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q9NRM7	LATS2	O14757	CHEK1	S380	D379G	379	Missense	proximal	-1	no	16.516	16.565	EPSD	COSMIC	5.604	Up-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q9NRM7	LATS2	O14757	CHEK1	S408	R415W	415	Missense	distal	7	no	10.512	10.011	EPSD;PhosphoSitePlus	COSMIC	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q9NRM7	LATS2	O14757	CHEK1	S408	S408C	408	Missense	central	0	yes	10.512	0.000	EPSD;PhosphoSitePlus	COSMIC	5.604	Loss
CAMK_CAMKL_CHK1_CHEK1_ST	Q9NRM7	LATS2	O14757	CHEK1	S408	P401Q	401	Missense	distal	-7	no	10.512	11.180	EPSD;PhosphoSitePlus	COSMIC	5.604	Up-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q9NRM7	LATS2	O14757	CHEK1	S446	V447L	447	Missense	proximal	1	no	6.887	6.885	EPSD	COSMIC	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q9NRM7	LATS2	O14757	CHEK1	S446	V447E	447	Missense	proximal	1	no	6.887	6.994	EPSD	COSMIC	5.604	Up-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q9NRM7	LATS2	O14757	CHEK1	S528	D532N	532	Missense	distal	4	no	11.224	11.193	EPSD	COSMIC	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q9NRM7	LATS2	O14757	CHEK1	S528	Q530L	530	Missense	proximal	2	no	11.224	10.396	EPSD	COSMIC	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q9NRM7	LATS2	O14757	CHEK1	S528	K527Q	527	Missense	proximal	-1	no	11.224	11.387	EPSD	COSMIC	5.604	Up-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q9NRM7	LATS2	O14757	CHEK1	S528	R525H	525	Missense	distal	-3	no	11.224	5.414	EPSD	COSMIC;GDSC;CCLE	5.604	Loss
CAMK_CAMKL_CHK1_CHEK1_ST	Q9NRM7	LATS2	O14757	CHEK1	S528	L533P	533	Missense	distal	5	no	11.224	11.385	EPSD	COSMIC	5.604	Up-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q9NRM7	LATS2	O14757	CHEK1	S598	S596R	596	Missense	proximal	-2	no	6.398	6.497	EPSD	COSMIC	5.604	Up-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q9NRM7	LATS2	O14757	CHEK1	S598	P599L	599	Missense	proximal	1	no	6.398	6.425	EPSD	COSMIC	5.604	Up-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q9NRM7	LATS2	O14757	CHEK1	S598	K595R	595	Missense	distal	-3	no	6.398	10.223	EPSD	COSMIC	5.604	Up-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q9NRM7	LATS2	O14757	CHEK1	S835	P838S	838	Missense	distal	3	no	7.876	7.547	PhosphoSitePlus;EPSD	COSMIC	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q9NRM7	LATS2	O14757	CHEK1	S839	D843G	843	Missense	distal	4	no	5.616	5.633	EPSD	COSMIC	5.604	Up-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q9NRM7	LATS2	O14757	CHEK1	S839	P838S	838	Missense	proximal	-1	no	5.616	5.169	EPSD	COSMIC	5.604	Loss
CAMK_CAMKL_CHK1_CHEK1_ST	Q5UIP0	RIF1	O14757	CHEK1	S7	P11T	11	Missense	distal	4	no	9.501	9.373	EPSD	COSMIC	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q5UIP0	RIF1	O14757	CHEK1	S740	D744N	744	Missense	distal	4	no	7.255	7.225	EPSD	COSMIC	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q5UIP0	RIF1	O14757	CHEK1	S740	S740Y	740	Missense	central	0	yes	7.255	0.000	EPSD	COSMIC	5.604	Loss
CAMK_CAMKL_CHK1_CHEK1_ST	Q5UIP0	RIF1	O14757	CHEK1	S782	K775E	775	Missense	distal	-7	no	6.330	5.633	EPSD	COSMIC	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q5UIP0	RIF1	O14757	CHEK1	S782	W789L	789	Missense	distal	7	no	6.330	6.731	EPSD	COSMIC	5.604	Up-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q5UIP0	RIF1	O14757	CHEK1	S782	R785T	785	Missense	distal	3	no	6.330	6.190	EPSD	COSMIC;GDSC;CCLE	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q5UIP0	RIF1	O14757	CHEK1	S802	E795K	795	Missense	distal	-7	no	10.559	11.256	EPSD	COSMIC	5.604	Up-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q5UIP0	RIF1	O14757	CHEK1	S802	K805I	805	Missense	distal	3	no	10.559	9.541	EPSD	COSMIC	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q5UIP0	RIF1	O14757	CHEK1	S1030	G1037C	1037	Missense	distal	7	no	8.098	7.687	EPSD	COSMIC	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q5UIP0	RIF1	O14757	CHEK1	S1046	L1040F	1040	Missense	distal	-6	no	5.521	5.771	EPSD	COSMIC	5.604	Gain
CAMK_CAMKL_CHK1_CHEK1_ST	Q5UIP0	RIF1	O14757	CHEK1	S1184	S1179L	1179	Missense	distal	-5	no	7.967	11.155	EPSD	COSMIC	5.604	Up-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q5UIP0	RIF1	O14757	CHEK1	S1184	S1184L	1184	Missense	central	0	yes	7.967	0.000	EPSD	COSMIC	5.604	Loss
CAMK_CAMKL_CHK1_CHEK1_ST	Q5UIP0	RIF1	O14757	CHEK1	S1184	R1181W	1181	Missense	distal	-3	no	7.967	-25.636	EPSD	COSMIC	5.604	Loss
CAMK_CAMKL_CHK1_CHEK1_ST	Q5UIP0	RIF1	O14757	CHEK1	S1189	S1184L	1184	Missense	distal	-5	no	4.280	7.468	EPSD	COSMIC	5.604	Gain
CAMK_CAMKL_CHK1_CHEK1_ST	Q5UIP0	RIF1	O14757	CHEK1	S1236	N1232S	1232	Missense	distal	-4	no	7.864	7.570	EPSD	COSMIC	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q5UIP0	RIF1	O14757	CHEK1	T1372	E1369A	1369	Missense	distal	-3	no	7.207	7.584	EPSD	COSMIC	5.604	Up-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q5UIP0	RIF1	O14757	CHEK1	T1372	E1375Q	1375	Missense	distal	3	no	7.207	6.807	EPSD	COSMIC	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q5UIP0	RIF1	O14757	CHEK1	T1372	E1375D	1375	Missense	distal	3	no	7.207	7.305	EPSD	COSMIC	5.604	Up-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q5UIP0	RIF1	O14757	CHEK1	T1372	V1373A	1373	Missense	proximal	1	no	7.207	7.231	EPSD	COSMIC	5.604	Up-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q5UIP0	RIF1	O14757	CHEK1	S1418	R1416Q	1416	Missense	proximal	-2	no	8.615	8.661	EPSD	COSMIC;CCLE	5.604	Up-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q5UIP0	RIF1	O14757	CHEK1	S1418	K1412I	1412	Missense	distal	-6	no	8.615	8.704	EPSD	COSMIC	5.604	Up-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q5UIP0	RIF1	O14757	CHEK1	S1418	R1416P	1416	Missense	proximal	-2	no	8.615	8.800	EPSD	COSMIC	5.604	Up-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q5UIP0	RIF1	O14757	CHEK1	S1422	R1416Q	1416	Missense	distal	-6	no	7.244	7.326	EPSD	COSMIC;CCLE	5.604	Up-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q5UIP0	RIF1	O14757	CHEK1	S1422	R1416P	1416	Missense	distal	-6	no	7.244	7.421	EPSD	COSMIC	5.604	Up-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q5UIP0	RIF1	O14757	CHEK1	S1437	E1430G	1430	Missense	distal	-7	no	7.019	6.574	EPSD	COSMIC;GDSC;CCLE	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q5UIP0	RIF1	O14757	CHEK1	T1534	Q1537K	1537	Missense	distal	3	no	11.148	10.732	EPSD	COSMIC	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q5UIP0	RIF1	O14757	CHEK1	T1534	Q1537H	1537	Missense	distal	3	no	11.148	10.116	EPSD	COSMIC	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q5UIP0	RIF1	O14757	CHEK1	T1538	Q1537K	1537	Missense	proximal	-1	no	7.580	7.416	EPSD	COSMIC	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q5UIP0	RIF1	O14757	CHEK1	T1538	Q1537H	1537	Missense	proximal	-1	no	7.580	7.690	EPSD	COSMIC	5.604	Up-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q5UIP0	RIF1	O14757	CHEK1	S1542	Q1537K	1537	Missense	distal	-5	no	5.816	7.388	EPSD	COSMIC	5.604	Up-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q5UIP0	RIF1	O14757	CHEK1	S1542	Q1537H	1537	Missense	distal	-5	no	5.816	3.747	EPSD	COSMIC	5.604	Loss
CAMK_CAMKL_CHK1_CHEK1_ST	Q5UIP0	RIF1	O14757	CHEK1	S1608	K1615I	1615	Missense	distal	7	no	6.922	6.462	EPSD	COSMIC;CCLE	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q5UIP0	RIF1	O14757	CHEK1	S1608	I1614T	1614	Missense	distal	6	no	6.922	7.190	EPSD	COSMIC	5.604	Up-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q5UIP0	RIF1	O14757	CHEK1	S1608	D1611H	1611	Missense	distal	3	no	6.922	5.393	EPSD	COSMIC	5.604	Loss
CAMK_CAMKL_CHK1_CHEK1_ST	Q5UIP0	RIF1	O14757	CHEK1	T1656	N1654I	1654	Missense	proximal	-2	no	6.845	6.784	EPSD	COSMIC	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q5UIP0	RIF1	O14757	CHEK1	S1688	S1693N	1693	Missense	distal	5	no	8.193	8.191	EPSD	COSMIC	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q5UIP0	RIF1	O14757	CHEK1	S1793	E1790D	1790	Missense	distal	-3	no	6.332	4.084	EPSD	COSMIC	5.604	Loss
CAMK_CAMKL_CHK1_CHEK1_ST	Q5UIP0	RIF1	O14757	CHEK1	S1793	D1789N	1789	Missense	distal	-4	no	6.332	6.256	EPSD	COSMIC	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q5UIP0	RIF1	O14757	CHEK1	S1793	H1797Y	1797	Missense	distal	4	no	6.332	6.294	EPSD	COSMIC	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q5UIP0	RIF1	O14757	CHEK1	T1822	P1828S	1828	Missense	distal	6	no	7.091	6.472	EPSD	COSMIC	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q5UIP0	RIF1	O14757	CHEK1	T1822	K1817E	1817	Missense	distal	-5	no	7.091	4.529	EPSD	COSMIC	5.604	Loss
CAMK_CAMKL_CHK1_CHEK1_ST	Q5UIP0	RIF1	O14757	CHEK1	S1826	P1828S	1828	Missense	proximal	2	no	6.399	6.476	EPSD	COSMIC	5.604	Up-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q5UIP0	RIF1	O14757	CHEK1	S2224	I2219L	2219	Missense	distal	-5	no	8.876	10.907	EPSD	COSMIC	5.604	Up-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q5UIP0	RIF1	O14757	CHEK1	S2224	D2217N	2217	Missense	distal	-7	no	8.876	8.569	EPSD	COSMIC	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q5UIP0	RIF1	O14757	CHEK1	S2393	S2391Y	2391	Missense	proximal	-2	no	6.016	6.128	EPSD	COSMIC	5.604	Up-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q5UIP0	RIF1	O14757	CHEK1	S2393	E2396D	2396	Missense	distal	3	no	6.016	6.113	EPSD	COSMIC	5.604	Up-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q5UIP0	RIF1	O14757	CHEK1	S2393	D2395N	2395	Missense	proximal	2	no	6.016	5.731	EPSD	COSMIC	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q5UIP0	RIF1	O14757	CHEK1	S2393	S2391F	2391	Missense	proximal	-2	no	6.016	6.305	EPSD	COSMIC	5.604	Up-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q5UIP0	RIF1	O14757	CHEK1	S2401	E2396D	2396	Missense	distal	-5	no	6.579	6.978	EPSD	COSMIC	5.604	Up-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q5UIP0	RIF1	O14757	CHEK1	S2401	D2395N	2395	Missense	distal	-6	no	6.579	6.792	EPSD	COSMIC	5.604	Up-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q5UIP0	RIF1	O14757	CHEK1	S2401	I2403M	2403	Missense	proximal	2	no	6.579	7.158	EPSD	COSMIC	5.604	Up-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q5UIP0	RIF1	O14757	CHEK1	S2465	L2459V	2459	Missense	distal	-6	no	6.321	6.308	EPSD	COSMIC	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q5UIP0	RIF1	O14757	CHEK1	S2465	R2462H	2462	Missense	distal	-3	no	6.321	0.511	EPSD	COSMIC	5.604	Loss
CAMK_CAMKL_CHK1_CHEK1_ST	Q5UIP0	RIF1	O14757	CHEK1	S2465	S2471T	2471	Missense	distal	6	no	6.321	6.631	EPSD	COSMIC	5.604	Up-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q5UIP0	RIF1	O14757	CHEK1	S2467	R2462H	2462	Missense	distal	-5	no	6.646	4.181	EPSD	COSMIC	5.604	Loss
CAMK_CAMKL_CHK1_CHEK1_ST	Q5UIP0	RIF1	O14757	CHEK1	S2467	S2471T	2471	Missense	distal	4	no	6.646	6.657	EPSD	COSMIC	5.604	Up-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q96GD4	AURKB	O14757	CHEK1	S45	V47D	47	Missense	proximal	2	no	5.374	5.947	EPSD	COSMIC	5.604	Gain
CAMK_CAMKL_CHK1_CHEK1_ST	Q96GD4	AURKB	O14757	CHEK1	T73	T69A	69	Missense	distal	-4	no	10.670	11.101	EPSD	COSMIC	5.604	Up-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q96GD4	AURKB	O14757	CHEK1	T73	T69N	69	Missense	distal	-4	no	10.670	11.015	EPSD	COSMIC	5.604	Up-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q96GD4	AURKB	O14757	CHEK1	T73	R70Q	70	Missense	distal	-3	no	10.670	3.463	EPSD	COSMIC	5.604	Loss
CAMK_CAMKL_CHK1_CHEK1_ST	Q96GD4	AURKB	O14757	CHEK1	T73	T69K	69	Missense	distal	-4	no	10.670	11.130	EPSD	COSMIC	5.604	Up-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q96GD4	AURKB	O14757	CHEK1	T73	F77L	77	Missense	distal	4	no	10.670	10.608	EPSD	COSMIC	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q96GD4	AURKB	O14757	CHEK1	T73	H71Y	71	Missense	proximal	-2	no	10.670	10.619	EPSD	COSMIC	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q96GD4	AURKB	O14757	CHEK1	T73	F72L	72	Missense	proximal	-1	no	10.670	10.657	EPSD	COSMIC	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q96GD4	AURKB	O14757	CHEK1	S313	E314K	314	Missense	proximal	1	no	8.877	8.803	EPSD	COSMIC	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q96GD4	AURKB	O14757	CHEK1	S331	R333W	333	Missense	proximal	2	no	7.984	7.810	PhosphoSitePlus	COSMIC	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q96GD4	AURKB	O14757	CHEK1	S331	P337L	337	Missense	distal	6	no	7.984	7.774	PhosphoSitePlus	COSMIC	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q96GD4	AURKB	O14757	CHEK1	S331	R333Q	333	Missense	proximal	2	no	7.984	8.513	PhosphoSitePlus	COSMIC	5.604	Up-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q96GD4	AURKB	O14757	CHEK1	S331	W326R	326	Missense	distal	-5	no	7.984	8.843	PhosphoSitePlus	COSMIC	5.604	Up-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q96GD4	AURKB	O14757	CHEK1	S331	R328Q	328	Missense	distal	-3	no	7.984	0.777	PhosphoSitePlus	COSMIC	5.604	Loss
CAMK_CAMKL_CHK1_CHEK1_ST	Q96GD4	AURKB	O14757	CHEK1	S331	P337S	337	Missense	distal	6	no	7.984	7.365	PhosphoSitePlus	COSMIC	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q96GD4	AURKB	O14757	CHEK1	S331	A329V	329	Missense	proximal	-2	no	7.984	8.061	PhosphoSitePlus	COSMIC	5.604	Up-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q96GD4	AURKB	O14757	CHEK1	S331	R333M	333	Missense	proximal	2	no	7.984	8.153	PhosphoSitePlus	COSMIC	5.604	Up-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q96GD4	AURKB	O14757	CHEK1	S331	R328W	328	Missense	distal	-3	no	7.984	-25.619	PhosphoSitePlus	COSMIC	5.604	Loss
CAMK_CAMKL_CHK1_CHEK1_ST	Q96GD4	AURKB	O14757	CHEK1	S331	R332W	332	Missense	proximal	1	no	7.984	7.954	PhosphoSitePlus	COSMIC	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q96GD4	AURKB	O14757	CHEK1	S331	W326L	326	Missense	distal	-5	no	7.984	11.820	PhosphoSitePlus	COSMIC	5.604	Up-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q96PK6	RBM14	O14757	CHEK1	S147	E145V	145	Missense	proximal	-2	no	5.557	5.687	EPSD	COSMIC	5.604	Gain
CAMK_CAMKL_CHK1_CHEK1_ST	Q96PK6	RBM14	O14757	CHEK1	S147	G150S	150	Missense	distal	3	no	5.557	5.644	EPSD	COSMIC	5.604	Gain
CAMK_CAMKL_CHK1_CHEK1_ST	Q96PK6	RBM14	O14757	CHEK1	S147	Q151P	151	Missense	distal	4	no	5.557	5.647	EPSD	COSMIC;GDSC	5.604	Gain
CAMK_CAMKL_CHK1_CHEK1_ST	Q96PK6	RBM14	O14757	CHEK1	S215	R218C	218	Missense	distal	3	no	10.265	9.318	EPSD	COSMIC	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q96PK6	RBM14	O14757	CHEK1	S215	R214H	214	Missense	proximal	-1	no	10.265	10.391	EPSD	COSMIC	5.604	Up-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q96PK6	RBM14	O14757	CHEK1	T231	T231M	231	Missense	central	0	yes	6.366	0.000	EPSD	COSMIC	5.604	Loss
CAMK_CAMKL_CHK1_CHEK1_ST	Q96PK6	RBM14	O14757	CHEK1	T231	T236I	236	Missense	distal	5	no	6.366	6.446	EPSD	COSMIC	5.604	Up-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q96PK6	RBM14	O14757	CHEK1	S294	G287C	287	Missense	distal	-7	no	5.932	5.166	EPSD	COSMIC;GDSC;CCLE	5.604	Loss
CAMK_CAMKL_CHK1_CHEK1_ST	Q96PK6	RBM14	O14757	CHEK1	S560	P554L	554	Missense	distal	-6	no	7.634	7.561	EPSD	COSMIC	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q96PK6	RBM14	O14757	CHEK1	S560	V566F	566	Missense	distal	6	no	7.634	7.761	EPSD	COSMIC	5.604	Up-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q96PK6	RBM14	O14757	CHEK1	S560	A565T	565	Missense	distal	5	no	7.634	7.393	EPSD	COSMIC	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q96PK6	RBM14	O14757	CHEK1	S618	R615H	615	Missense	distal	-3	no	7.059	1.249	EPSD;PhosphoSitePlus	COSMIC	5.604	Loss
CAMK_CAMKL_CHK1_CHEK1_ST	Q96PK6	RBM14	O14757	CHEK1	S627	S631P	631	Missense	distal	4	no	7.028	7.168	PhosphoSitePlus;EPSD	COSMIC	5.604	Up-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q96PK6	RBM14	O14757	CHEK1	T629	S631P	631	Missense	proximal	2	no	10.671	10.594	EPSD;PhosphoSitePlus	COSMIC	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q13907	IDI1	O14757	CHEK1	S55	T61I	61	Missense	distal	6	no	14.294	14.026	PhosphoSitePlus	COSMIC	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q13907	IDI1	O14757	CHEK1	S55	R52Q	52	Missense	distal	-3	no	14.294	7.087	PhosphoSitePlus	COSMIC	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q13907	IDI1	O14757	CHEK1	S55	L49F	49	Missense	distal	-6	no	14.294	14.543	PhosphoSitePlus	COSMIC	5.604	Up-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q13907	IDI1	O14757	CHEK1	S55	L50S	50	Missense	distal	-5	no	14.294	11.106	PhosphoSitePlus	COSMIC	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q13907	IDI1	O14757	CHEK1	S188	T194M	194	Missense	distal	6	no	11.910	12.000	EPSD	COSMIC	5.604	Up-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q13907	IDI1	O14757	CHEK1	S188	P195L	195	Missense	distal	7	no	11.910	11.847	EPSD	COSMIC	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q13907	IDI1	O14757	CHEK1	S188	E190K	190	Missense	proximal	2	no	11.910	11.951	EPSD	COSMIC	5.604	Up-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	O14757	CHEK1	O14757	CHEK1	T378	K375R	375	Missense	distal	-3	no	6.209	10.035	PhosphoSitePlus	COSMIC	5.604	Up-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	O14757	CHEK1	O14757	CHEK1	T378	R372W	372	Missense	distal	-6	no	6.209	6.529	PhosphoSitePlus	COSMIC	5.604	Up-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	O14757	CHEK1	O14757	CHEK1	T378	V374F	374	Missense	distal	-4	no	6.209	5.667	PhosphoSitePlus	COSMIC	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	O14757	CHEK1	O14757	CHEK1	T378	T382S	382	Missense	distal	4	no	6.209	6.198	PhosphoSitePlus	COSMIC	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	O14757	CHEK1	O14757	CHEK1	T378	L384F	384	Missense	distal	6	no	6.209	6.203	PhosphoSitePlus	COSMIC	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	O14757	CHEK1	O14757	CHEK1	T378	M377I	377	Missense	proximal	-1	no	6.209	6.116	PhosphoSitePlus	COSMIC	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	O14757	CHEK1	O14757	CHEK1	T378	K375Q	375	Missense	distal	-3	no	6.209	2.828	PhosphoSitePlus	COSMIC	5.604	Loss
CAMK_CAMKL_CHK1_CHEK1_ST	Q9H8G2	CAAP1	O14757	CHEK1	S7	G3A	3	Missense	distal	-4	no	5.962	6.007	EPSD	COSMIC	5.604	Up-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q9H8G2	CAAP1	O14757	CHEK1	S7	R8W	8	Missense	proximal	1	no	5.962	5.932	EPSD	COSMIC	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q9H8G2	CAAP1	O14757	CHEK1	S7	R8Q	8	Missense	proximal	1	no	5.962	5.970	EPSD	COSMIC	5.604	Up-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q9Y520	PRRC2C	O14757	CHEK1	S191	E195K	195	Missense	distal	4	no	7.641	7.635	EPSD	COSMIC	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q9Y520	PRRC2C	O14757	CHEK1	S191	G186D	186	Missense	distal	-5	no	7.641	6.819	EPSD	COSMIC	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q9Y520	PRRC2C	O14757	CHEK1	S208	E209Q	209	Missense	proximal	1	no	6.325	6.259	EPSD	COSMIC;CCLE	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q9Y520	PRRC2C	O14757	CHEK1	S208	D201N	201	Missense	distal	-7	no	6.325	6.017	EPSD	COSMIC	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q9Y520	PRRC2C	O14757	CHEK1	S344	G341R	341	Missense	distal	-3	no	0.913	8.687	EPSD	COSMIC	5.604	Gain
CAMK_CAMKL_CHK1_CHEK1_ST	Q9Y520	PRRC2C	O14757	CHEK1	S403	T402I	402	Missense	proximal	-1	no	8.824	8.737	EPSD	COSMIC	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q9Y520	PRRC2C	O14757	CHEK1	S403	L406P	406	Missense	distal	3	no	8.824	9.588	EPSD	COSMIC	5.604	Up-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q9Y520	PRRC2C	O14757	CHEK1	S403	S404L	404	Missense	proximal	1	no	8.824	8.815	EPSD	COSMIC	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q9Y520	PRRC2C	O14757	CHEK1	S453	Q451H	451	Missense	proximal	-2	no	8.461	8.480	EPSD	COSMIC	5.604	Up-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q9Y520	PRRC2C	O14757	CHEK1	S453	R450I	450	Missense	distal	-3	no	8.461	-0.297	EPSD	COSMIC	5.604	Loss
CAMK_CAMKL_CHK1_CHEK1_ST	Q9Y520	PRRC2C	O14757	CHEK1	S453	S456T	456	Missense	distal	3	no	8.461	8.318	EPSD	COSMIC	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q9Y520	PRRC2C	O14757	CHEK1	S500	P499A	499	Missense	proximal	-1	no	8.114	8.000	EPSD	COSMIC	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q9Y520	PRRC2C	O14757	CHEK1	S500	G493C	493	Missense	distal	-7	no	8.114	7.348	EPSD	COSMIC	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q9Y520	PRRC2C	O14757	CHEK1	S500	E506D	506	Missense	distal	6	no	8.114	8.200	EPSD	COSMIC	5.604	Up-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q9Y520	PRRC2C	O14757	CHEK1	S500	R507T	507	Missense	distal	7	no	8.114	7.954	EPSD	COSMIC	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q9Y520	PRRC2C	O14757	CHEK1	S633	S633N	633	Missense	central	0	yes	5.644	0.000	EPSD	COSMIC	5.604	Loss
CAMK_CAMKL_CHK1_CHEK1_ST	Q9Y520	PRRC2C	O14757	CHEK1	S633	Q631L	631	Missense	proximal	-2	no	5.644	5.604	EPSD	COSMIC;CCLE	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q9Y520	PRRC2C	O14757	CHEK1	S633	P626T	626	Missense	distal	-7	no	5.644	5.447	EPSD	COSMIC	5.604	Loss
CAMK_CAMKL_CHK1_CHEK1_ST	Q9Y520	PRRC2C	O14757	CHEK1	S799	A797T	797	Missense	proximal	-2	no	5.549	5.689	EPSD	COSMIC	5.604	Gain
CAMK_CAMKL_CHK1_CHEK1_ST	Q9Y520	PRRC2C	O14757	CHEK1	S799	A793T	793	Missense	distal	-6	no	5.549	5.745	EPSD	COSMIC	5.604	Gain
CAMK_CAMKL_CHK1_CHEK1_ST	Q9Y520	PRRC2C	O14757	CHEK1	S799	L806P	806	Missense	distal	7	no	5.549	5.612	EPSD	COSMIC	5.604	Gain
CAMK_CAMKL_CHK1_CHEK1_ST	Q9Y520	PRRC2C	O14757	CHEK1	T826	E830K	830	Missense	distal	4	no	6.156	6.150	EPSD	COSMIC	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q9Y520	PRRC2C	O14757	CHEK1	T826	V832A	832	Missense	distal	6	no	6.156	6.268	EPSD	COSMIC	5.604	Up-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q9Y520	PRRC2C	O14757	CHEK1	S876	S878P	878	Missense	proximal	2	no	6.991	6.914	EPSD	COSMIC	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q9Y520	PRRC2C	O14757	CHEK1	S905	A906S	906	Missense	proximal	1	no	7.115	7.097	EPSD	COSMIC	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q9Y520	PRRC2C	O14757	CHEK1	S905	A906T	906	Missense	proximal	1	no	7.115	7.105	EPSD	COSMIC	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q9Y520	PRRC2C	O14757	CHEK1	S924	R923I	923	Missense	proximal	-1	no	8.986	8.942	EPSD	COSMIC;CCLE	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q9Y520	PRRC2C	O14757	CHEK1	S924	H927P	927	Missense	distal	3	no	8.986	9.287	EPSD	COSMIC	5.604	Up-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q9Y520	PRRC2C	O14757	CHEK1	S924	S926T	926	Missense	proximal	2	no	8.986	8.594	EPSD	COSMIC	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q9Y520	PRRC2C	O14757	CHEK1	S924	S926C	926	Missense	proximal	2	no	8.986	8.624	EPSD	COSMIC	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q9Y520	PRRC2C	O14757	CHEK1	S926	R923I	923	Missense	distal	-3	no	9.532	0.774	EPSD	COSMIC;CCLE	5.604	Loss
CAMK_CAMKL_CHK1_CHEK1_ST	Q9Y520	PRRC2C	O14757	CHEK1	S926	H927P	927	Missense	proximal	1	no	9.532	9.535	EPSD	COSMIC	5.604	Up-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q9Y520	PRRC2C	O14757	CHEK1	S926	S926C	926	Missense	central	0	yes	9.532	0.000	EPSD	COSMIC	5.604	Loss
CAMK_CAMKL_CHK1_CHEK1_ST	Q9Y520	PRRC2C	O14757	CHEK1	S999	R1002K	1002	Missense	distal	3	no	6.359	7.006	EPSD	COSMIC	5.604	Up-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q9Y520	PRRC2C	O14757	CHEK1	S999	G994S	994	Missense	distal	-5	no	6.359	6.313	EPSD	COSMIC	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q9Y520	PRRC2C	O14757	CHEK1	S999	R1002M	1002	Missense	distal	3	no	6.359	6.275	EPSD	COSMIC	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q9Y520	PRRC2C	O14757	CHEK1	S999	W993L	993	Missense	distal	-6	no	6.359	6.144	EPSD	COSMIC	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q9Y520	PRRC2C	O14757	CHEK1	S999	N1000K	1000	Missense	proximal	1	no	6.359	6.388	EPSD	COSMIC	5.604	Up-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q9Y520	PRRC2C	O14757	CHEK1	S999	P997S	997	Missense	proximal	-2	no	6.359	6.075	EPSD	COSMIC;CCLE	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q9Y520	PRRC2C	O14757	CHEK1	S1155	K1161Q	1161	Missense	distal	6	no	7.537	7.618	EPSD	COSMIC;CCLE	5.604	Up-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q9Y520	PRRC2C	O14757	CHEK1	T1215	R1212T	1212	Missense	distal	-3	no	9.178	-11.390	EPSD	COSMIC	5.604	Loss
CAMK_CAMKL_CHK1_CHEK1_ST	Q9Y520	PRRC2C	O14757	CHEK1	T1215	G1211S	1211	Missense	distal	-4	no	9.178	8.844	EPSD	COSMIC	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q9Y520	PRRC2C	O14757	CHEK1	T1215	G1211V	1211	Missense	distal	-4	no	9.178	9.144	EPSD	COSMIC	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q9Y520	PRRC2C	O14757	CHEK1	T1215	G1213V	1213	Missense	proximal	-2	no	9.178	9.237	EPSD	COSMIC	5.604	Up-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q9Y520	PRRC2C	O14757	CHEK1	T1215	H1214Q	1214	Missense	proximal	-1	no	9.178	9.068	EPSD	COSMIC;CCLE	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q9Y520	PRRC2C	O14757	CHEK1	T1215	R1212G	1212	Missense	distal	-3	no	9.178	1.404	EPSD	COSMIC	5.604	Loss
CAMK_CAMKL_CHK1_CHEK1_ST	Q9Y520	PRRC2C	O14757	CHEK1	T1215	G1213S	1213	Missense	proximal	-2	no	9.178	9.046	EPSD	COSMIC	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q9Y520	PRRC2C	O14757	CHEK1	S1242	R1245W	1245	Missense	distal	3	no	7.926	7.788	EPSD	COSMIC	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q9Y520	PRRC2C	O14757	CHEK1	S1242	R1245Q	1245	Missense	distal	3	no	7.926	8.988	EPSD	COSMIC	5.604	Up-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q9Y520	PRRC2C	O14757	CHEK1	S1248	R1245W	1245	Missense	distal	-3	no	7.198	-26.405	EPSD	COSMIC	5.604	Loss
CAMK_CAMKL_CHK1_CHEK1_ST	Q9Y520	PRRC2C	O14757	CHEK1	S1248	R1245Q	1245	Missense	distal	-3	no	7.198	-0.009	EPSD	COSMIC	5.604	Loss
CAMK_CAMKL_CHK1_CHEK1_ST	Q9Y520	PRRC2C	O14757	CHEK1	S1248	V1254I	1254	Missense	distal	6	no	7.198	6.964	EPSD	COSMIC	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q9Y520	PRRC2C	O14757	CHEK1	T1364	R1358H	1358	Missense	distal	-6	no	6.899	7.008	EPSD	COSMIC;CCLE	5.604	Up-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q9Y520	PRRC2C	O14757	CHEK1	T1364	R1371W	1371	Missense	distal	7	no	6.899	6.397	EPSD	COSMIC	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q9Y520	PRRC2C	O14757	CHEK1	T1364	R1366Q	1366	Missense	proximal	2	no	6.899	7.427	EPSD	COSMIC	5.604	Up-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q9Y520	PRRC2C	O14757	CHEK1	T1364	L1365V	1365	Missense	proximal	1	no	6.899	6.901	EPSD	COSMIC	5.604	Up-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q9Y520	PRRC2C	O14757	CHEK1	T1364	R1371Q	1371	Missense	distal	7	no	6.899	7.053	EPSD	COSMIC	5.604	Up-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q9Y520	PRRC2C	O14757	CHEK1	S1488	P1481S	1481	Missense	distal	-7	no	5.267	5.937	EPSD	COSMIC	5.604	Gain
CAMK_CAMKL_CHK1_CHEK1_ST	Q9Y520	PRRC2C	O14757	CHEK1	S1544	R1551H	1551	Missense	distal	7	no	9.518	9.225	EPSD	COSMIC	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q9Y520	PRRC2C	O14757	CHEK1	S1544	E1537D	1537	Missense	distal	-7	no	9.518	9.065	EPSD	COSMIC	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q9Y520	PRRC2C	O14757	CHEK1	S1568	R1571G	1571	Missense	distal	3	no	9.330	9.245	EPSD	COSMIC;CCLE	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q9Y520	PRRC2C	O14757	CHEK1	S1568	N1572K	1572	Missense	distal	4	no	9.330	9.263	EPSD	COSMIC	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q9Y520	PRRC2C	O14757	CHEK1	S1568	P1561F	1561	Missense	distal	-7	no	9.330	8.268	EPSD	COSMIC	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q9Y520	PRRC2C	O14757	CHEK1	S1568	R1575K	1575	Missense	distal	7	no	9.330	9.405	EPSD	COSMIC	5.604	Up-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q9Y520	PRRC2C	O14757	CHEK1	T1625	S1624P	1624	Missense	proximal	-1	no	7.071	7.518	EPSD	COSMIC	5.604	Up-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q9Y520	PRRC2C	O14757	CHEK1	T1625	K1622R	1622	Missense	distal	-3	no	7.071	10.897	EPSD	COSMIC	5.604	Up-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q9Y520	PRRC2C	O14757	CHEK1	T1625	G1626W	1626	Missense	proximal	1	no	7.071	7.050	EPSD	COSMIC	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q9Y520	PRRC2C	O14757	CHEK1	T1625	S1624C	1624	Missense	proximal	-1	no	7.071	7.267	EPSD	COSMIC	5.604	Up-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q9Y520	PRRC2C	O14757	CHEK1	S1962	I1958V	1958	Missense	distal	-4	no	7.933	8.213	EPSD	COSMIC	5.604	Up-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q9Y520	PRRC2C	O14757	CHEK1	S2122	P2116S	2116	Missense	distal	-6	no	9.468	9.371	EPSD	COSMIC	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q9Y520	PRRC2C	O14757	CHEK1	S2506	G2507D	2507	Missense	proximal	1	no	6.287	6.375	EPSD	COSMIC;CCLE	5.604	Up-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q9Y520	PRRC2C	O14757	CHEK1	S2506	A2502S	2502	Missense	distal	-4	no	6.287	5.908	EPSD	COSMIC	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q9Y520	PRRC2C	O14757	CHEK1	S2577	Q2574K	2574	Missense	distal	-3	no	2.778	6.159	EPSD	COSMIC	5.604	Gain
CAMK_CAMKL_CHK1_CHEK1_ST	Q9Y520	PRRC2C	O14757	CHEK1	S2665	D2668H	2668	Missense	distal	3	no	6.843	5.314	EPSD	COSMIC;CCLE	5.604	Loss
CAMK_CAMKL_CHK1_CHEK1_ST	Q9Y520	PRRC2C	O14757	CHEK1	S2692	P2687L	2687	Missense	distal	-5	no	8.173	12.880	EPSD	COSMIC	5.604	Up-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q9Y520	PRRC2C	O14757	CHEK1	S2692	S2694G	2694	Missense	proximal	2	no	8.173	8.108	EPSD	COSMIC	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q9NS23	RASSF1	O14757	CHEK1	S179	P181S	181	Missense	proximal	2	no	12.253	12.329	EPSD	COSMIC;GDSC;CCLE	5.604	Up-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q9NS23	RASSF1	O14757	CHEK1	S179	P177S	177	Missense	proximal	-2	no	12.253	11.969	EPSD	COSMIC	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q9NS23	RASSF1	O14757	CHEK1	S179	S179R	179	Missense	central	0	yes	12.253	0.000	EPSD	COSMIC	5.604	Loss
CAMK_CAMKL_CHK1_CHEK1_ST	Q9NS23	RASSF1	O14757	CHEK1	S179	R176C	176	Missense	distal	-3	no	12.253	4.161	EPSD	COSMIC;GDSC	5.604	Loss
CAMK_CAMKL_CHK1_CHEK1_ST	Q9NS23	RASSF1	O14757	CHEK1	S179	S183R	183	Missense	distal	4	no	12.253	12.303	EPSD	COSMIC	5.604	Up-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q9NS23	RASSF1	O14757	CHEK1	S179	R176H	176	Missense	distal	-3	no	12.253	6.443	EPSD	COSMIC	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q9NS23	RASSF1	O14757	CHEK1	S182	S179R	179	Missense	distal	-3	no	0.543	10.239	EPSD	COSMIC	5.604	Gain
CAMK_CAMKL_CHK1_CHEK1_ST	Q9NS23	RASSF1	O14757	CHEK1	S188	P181S	181	Missense	distal	-7	no	9.034	9.704	EPSD	COSMIC;GDSC;CCLE	5.604	Up-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q9NS23	RASSF1	O14757	CHEK1	S188	R193W	193	Missense	distal	5	no	9.034	8.866	EPSD	COSMIC	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q9NS23	RASSF1	O14757	CHEK1	S188	A192V	192	Missense	distal	4	no	9.034	8.952	EPSD	COSMIC	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q9NS23	RASSF1	O14757	CHEK1	S188	L189Q	189	Missense	proximal	1	no	9.034	9.078	EPSD	COSMIC	5.604	Up-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q9NS23	RASSF1	O14757	CHEK1	S188	S183R	183	Missense	distal	-5	no	9.034	9.246	EPSD	COSMIC	5.604	Up-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q9NS23	RASSF1	O14757	CHEK1	S188	R194Q	194	Missense	distal	6	no	9.034	9.028	EPSD	COSMIC	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q9NS23	RASSF1	O14757	CHEK1	S201	R205H	205	Missense	distal	4	no	6.475	6.636	EPSD	COSMIC;CCLE	5.604	Up-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q9NS23	RASSF1	O14757	CHEK1	S201	T200I	200	Missense	proximal	-1	no	6.475	6.388	EPSD	COSMIC	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q9NS23	RASSF1	O14757	CHEK1	S201	G197R	197	Missense	distal	-4	no	6.475	6.449	EPSD	COSMIC	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q9NS23	RASSF1	O14757	CHEK1	S201	R194Q	194	Missense	distal	-7	no	6.475	6.733	EPSD	COSMIC	5.604	Up-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q9NS23	RASSF1	O14757	CHEK1	T206	R205H	205	Missense	proximal	-1	no	5.700	5.825	EPSD	COSMIC;CCLE	5.604	Up-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q9NS23	RASSF1	O14757	CHEK1	T206	T200I	200	Missense	distal	-6	no	5.700	5.629	EPSD	COSMIC	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	O75151	PHF2	O14757	CHEK1	S705	A712D	712	Missense	distal	7	no	5.433	5.775	EPSD	COSMIC	5.604	Gain
CAMK_CAMKL_CHK1_CHEK1_ST	O75151	PHF2	O14757	CHEK1	S899	P906Q	906	Missense	distal	7	no	10.805	10.997	EPSD	COSMIC	5.604	Up-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	O75151	PHF2	O14757	CHEK1	S899	Y904F	904	Missense	distal	5	no	10.805	10.934	EPSD	COSMIC	5.604	Up-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	O75151	PHF2	O14757	CHEK1	S929	R926Q	926	Missense	distal	-3	no	8.732	1.525	PhosphoSitePlus	COSMIC	5.604	Loss
CAMK_CAMKL_CHK1_CHEK1_ST	O75151	PHF2	O14757	CHEK1	S929	R922S	922	Missense	distal	-7	no	8.732	8.991	PhosphoSitePlus	COSMIC	5.604	Up-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	O75151	PHF2	O14757	CHEK1	S1056	R1054Q	1054	Missense	proximal	-2	no	10.666	10.712	EPSD	COSMIC;CCLE	5.604	Up-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	O75151	PHF2	O14757	CHEK1	S1058	R1054Q	1054	Missense	distal	-4	no	6.255	6.415	EPSD	COSMIC;CCLE	5.604	Up-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	P52272	HNRNPM	O14757	CHEK1	S225	V230M	230	Missense	distal	5	no	7.770	7.743	EPSD	COSMIC	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	P52272	HNRNPM	O14757	CHEK1	S365	R371C	371	Missense	distal	6	no	10.196	10.490	EPSD	COSMIC	5.604	Up-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	P52272	HNRNPM	O14757	CHEK1	S432	R429H	429	Missense	distal	-3	no	8.821	3.012	PhosphoSitePlus	COSMIC	5.604	Loss
CAMK_CAMKL_CHK1_CHEK1_ST	P52272	HNRNPM	O14757	CHEK1	S432	G426D	426	Missense	distal	-6	no	8.821	8.611	PhosphoSitePlus	COSMIC	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	P52272	HNRNPM	O14757	CHEK1	S432	G426S	426	Missense	distal	-6	no	8.821	8.784	PhosphoSitePlus	COSMIC	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	P52272	HNRNPM	O14757	CHEK1	S432	G426C	426	Missense	distal	-6	no	8.821	8.819	PhosphoSitePlus	COSMIC	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	P52272	HNRNPM	O14757	CHEK1	S432	E433Q	433	Missense	proximal	1	no	8.821	8.755	PhosphoSitePlus	COSMIC;GDSC;CCLE	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	P52272	HNRNPM	O14757	CHEK1	S446	E448Q	448	Missense	proximal	2	no	8.749	8.633	EPSD	COSMIC	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	P52272	HNRNPM	O14757	CHEK1	S446	R449H	449	Missense	distal	3	no	8.749	8.779	EPSD	COSMIC	5.604	Up-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	P52272	HNRNPM	O14757	CHEK1	S446	V447M	447	Missense	proximal	1	no	8.749	8.741	EPSD	COSMIC	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	P52272	HNRNPM	O14757	CHEK1	S452	E448Q	448	Missense	distal	-4	no	10.492	10.449	EPSD	COSMIC	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	P52272	HNRNPM	O14757	CHEK1	S452	M450V	450	Missense	proximal	-2	no	10.492	10.542	EPSD	COSMIC	5.604	Up-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	P52272	HNRNPM	O14757	CHEK1	S452	G458C	458	Missense	distal	6	no	10.492	10.662	EPSD	COSMIC	5.604	Up-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	P52272	HNRNPM	O14757	CHEK1	S452	R449H	449	Missense	distal	-3	no	10.492	4.683	EPSD	COSMIC	5.604	Loss
CAMK_CAMKL_CHK1_CHEK1_ST	P52272	HNRNPM	O14757	CHEK1	S452	V447M	447	Missense	distal	-5	no	10.492	9.596	EPSD	COSMIC	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	P52272	HNRNPM	O14757	CHEK1	S467	A466T	466	Missense	proximal	-1	no	6.839	6.711	EPSD	COSMIC	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	P52272	HNRNPM	O14757	CHEK1	S467	M472L	472	Missense	distal	5	no	6.839	6.708	EPSD	COSMIC	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	P52272	HNRNPM	O14757	CHEK1	S467	G473V	473	Missense	distal	6	no	6.839	6.903	EPSD	COSMIC	5.604	Up-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	P52272	HNRNPM	O14757	CHEK1	S467	G473D	473	Missense	distal	6	no	6.839	6.443	EPSD	COSMIC	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	P52272	HNRNPM	O14757	CHEK1	S467	R471C	471	Missense	distal	4	no	6.839	6.943	EPSD	COSMIC	5.604	Up-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	P52272	HNRNPM	O14757	CHEK1	S468	A466T	466	Missense	proximal	-2	no	6.452	6.592	EPSD	COSMIC	5.604	Up-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	P52272	HNRNPM	O14757	CHEK1	S468	M472L	472	Missense	distal	4	no	6.452	6.379	EPSD	COSMIC	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	P52272	HNRNPM	O14757	CHEK1	S468	G473V	473	Missense	distal	5	no	6.452	6.558	EPSD	COSMIC	5.604	Up-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	P52272	HNRNPM	O14757	CHEK1	S468	G473D	473	Missense	distal	5	no	6.452	6.731	EPSD	COSMIC	5.604	Up-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	P52272	HNRNPM	O14757	CHEK1	S468	R471C	471	Missense	distal	3	no	6.452	5.505	EPSD	COSMIC	5.604	Loss
CAMK_CAMKL_CHK1_CHEK1_ST	P52272	HNRNPM	O14757	CHEK1	S481	E477Q	477	Missense	distal	-4	no	10.530	10.486	EPSD	COSMIC	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	P52272	HNRNPM	O14757	CHEK1	S513	R510H	510	Missense	distal	-3	no	13.070	7.261	EPSD	COSMIC	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	P52272	HNRNPM	O14757	CHEK1	S513	Q506R	506	Missense	distal	-7	no	13.070	12.812	EPSD	COSMIC	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	P52272	HNRNPM	O14757	CHEK1	S513	M511I	511	Missense	proximal	-2	no	13.070	13.056	EPSD	COSMIC	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	P52272	HNRNPM	O14757	CHEK1	S513	R510C	510	Missense	distal	-3	no	13.070	4.979	EPSD	COSMIC	5.604	Loss
CAMK_CAMKL_CHK1_CHEK1_ST	P52272	HNRNPM	O14757	CHEK1	S528	A535V	535	Missense	distal	7	no	6.152	6.231	EPSD	COSMIC	5.604	Up-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	P52272	HNRNPM	O14757	CHEK1	S528	L527P	527	Missense	proximal	-1	no	6.152	6.339	EPSD	COSMIC	5.604	Up-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	P52272	HNRNPM	O14757	CHEK1	S528	V533A	533	Missense	distal	5	no	6.152	6.256	EPSD	COSMIC	5.604	Up-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	P52272	HNRNPM	O14757	CHEK1	S528	R531H	531	Missense	distal	3	no	6.152	6.183	EPSD	COSMIC	5.604	Up-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	P52272	HNRNPM	O14757	CHEK1	T553	V547M	547	Missense	distal	-6	no	9.689	9.739	EPSD	COSMIC	5.604	Up-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	P52272	HNRNPM	O14757	CHEK1	S701	C694G	694	Missense	distal	-7	no	6.393	7.159	EPSD	COSMIC	5.604	Up-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	P52272	HNRNPM	O14757	CHEK1	S701	A705T	705	Missense	distal	4	no	6.393	6.211	EPSD	COSMIC	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q15648	MED1	O14757	CHEK1	S18	M16I	16	Missense	proximal	-2	no	8.941	8.927	EPSD	COSMIC	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q15648	MED1	O14757	CHEK1	S256	M253V	253	Missense	distal	-3	no	6.456	3.141	EPSD	COSMIC;GDSC	5.604	Loss
CAMK_CAMKL_CHK1_CHEK1_ST	Q15648	MED1	O14757	CHEK1	S434	G436V	436	Missense	proximal	2	no	6.500	6.459	EPSD	COSMIC	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q15648	MED1	O14757	CHEK1	S545	P542Q	542	Missense	distal	-3	no	6.816	6.746	EPSD	COSMIC	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q15648	MED1	O14757	CHEK1	S588	R585Q	585	Missense	distal	-3	no	10.283	3.076	EPSD	COSMIC	5.604	Loss
CAMK_CAMKL_CHK1_CHEK1_ST	Q15648	MED1	O14757	CHEK1	S671	S673F	673	Missense	proximal	2	no	12.462	12.318	EPSD	COSMIC	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q15648	MED1	O14757	CHEK1	T704	D706H	706	Missense	proximal	2	no	7.190	6.647	PhosphoSitePlus	COSMIC	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q15648	MED1	O14757	CHEK1	S951	G955S	955	Missense	distal	4	no	8.786	8.719	EPSD	COSMIC	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q15648	MED1	O14757	CHEK1	S951	H950Y	950	Missense	proximal	-1	no	8.786	8.828	EPSD	COSMIC	5.604	Up-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q15648	MED1	O14757	CHEK1	T998	G993E	993	Missense	distal	-5	no	6.888	5.666	EPSD	COSMIC	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q15648	MED1	O14757	CHEK1	T998	T998I	998	Missense	central	0	yes	6.888	0.000	EPSD	COSMIC	5.604	Loss
CAMK_CAMKL_CHK1_CHEK1_ST	Q15648	MED1	O14757	CHEK1	T998	S1000F	1000	Missense	proximal	2	no	6.888	6.743	EPSD	COSMIC	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q15648	MED1	O14757	CHEK1	S1000	G993E	993	Missense	distal	-7	no	10.031	10.475	EPSD	COSMIC	5.604	Up-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q15648	MED1	O14757	CHEK1	S1000	T998I	998	Missense	proximal	-2	no	10.031	9.905	EPSD	COSMIC	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q15648	MED1	O14757	CHEK1	S1000	S1000F	1000	Missense	central	0	yes	10.031	0.000	EPSD	COSMIC	5.604	Loss
CAMK_CAMKL_CHK1_CHEK1_ST	Q15648	MED1	O14757	CHEK1	S1207	G1214E	1214	Missense	distal	7	no	5.984	6.218	EPSD	COSMIC	5.604	Up-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q16204	CCDC6	O14757	CHEK1	S65	L59F	59	Missense	distal	-6	no	12.699	12.948	EPSD	COSMIC	5.604	Up-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q16204	CCDC6	O14757	CHEK1	S240	P242S	242	Missense	proximal	2	no	6.503	6.580	EPSD;PhosphoSitePlus	COSMIC	5.604	Up-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q16204	CCDC6	O14757	CHEK1	S240	V239A	239	Missense	proximal	-1	no	6.503	6.581	EPSD;PhosphoSitePlus	COSMIC;GDSC	5.604	Up-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q16204	CCDC6	O14757	CHEK1	S244	P242S	242	Missense	proximal	-2	no	5.651	5.367	PhosphoSitePlus;EPSD	COSMIC	5.604	Loss
CAMK_CAMKL_CHK1_CHEK1_ST	Q16204	CCDC6	O14757	CHEK1	S244	V239A	239	Missense	distal	-5	no	5.651	3.212	PhosphoSitePlus;EPSD	COSMIC;GDSC	5.604	Loss
CAMK_CAMKL_CHK1_CHEK1_ST	Q16204	CCDC6	O14757	CHEK1	S249	P242S	242	Missense	distal	-7	no	9.198	9.868	EPSD	COSMIC	5.604	Up-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q16204	CCDC6	O14757	CHEK1	S323	E324K	324	Missense	proximal	1	no	12.375	12.301	EPSD	COSMIC	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q16204	CCDC6	O14757	CHEK1	S327	E324K	324	Missense	distal	-3	no	5.399	8.662	EPSD	COSMIC	5.604	Gain
CAMK_CAMKL_CHK1_CHEK1_ST	Q16204	CCDC6	O14757	CHEK1	S419	R415W	415	Missense	distal	-4	no	6.785	6.023	EPSD	COSMIC	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q16204	CCDC6	O14757	CHEK1	S419	P412H	412	Missense	distal	-7	no	6.785	7.136	EPSD	COSMIC	5.604	Up-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q16204	CCDC6	O14757	CHEK1	S419	R425Q	425	Missense	distal	6	no	6.785	6.779	EPSD	COSMIC	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q9Y2T7	YBX2	O14757	CHEK1	T115	D118N	118	Missense	distal	3	no	11.717	11.001	PhosphoSitePlus	COSMIC	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	O95785	WIZ	O14757	CHEK1	S886	R890W	890	Missense	distal	4	no	5.688	5.751	EPSD	COSMIC	5.604	Up-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	O95785	WIZ	O14757	CHEK1	S886	R890L	890	Missense	distal	4	no	5.688	5.674	EPSD	COSMIC	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	O95785	WIZ	O14757	CHEK1	S886	R882W	882	Missense	distal	-4	no	5.688	4.926	EPSD	COSMIC	5.604	Loss
CAMK_CAMKL_CHK1_CHEK1_ST	O95785	WIZ	O14757	CHEK1	S1129	D1130N	1130	Missense	proximal	1	no	7.695	7.587	PhosphoSitePlus	COSMIC	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	O95785	WIZ	O14757	CHEK1	S1391	T1385M	1385	Missense	distal	-6	no	7.047	7.039	EPSD	COSMIC	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	O95785	WIZ	O14757	CHEK1	S1468	G1472C	1472	Missense	distal	4	no	5.685	5.772	EPSD	COSMIC	5.604	Up-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q86WB0	ZC3HC1	O14757	CHEK1	T84	R81G	81	Missense	distal	-3	no	10.986	3.211	PhosphoSitePlus	COSMIC	5.604	Loss
CAMK_CAMKL_CHK1_CHEK1_ST	Q86WB0	ZC3HC1	O14757	CHEK1	T84	F85L	85	Missense	proximal	1	no	10.986	10.982	PhosphoSitePlus	COSMIC	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q86WB0	ZC3HC1	O14757	CHEK1	S354	T352I	352	Missense	proximal	-2	no	10.381	10.255	EPSD	COSMIC	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q86WB0	ZC3HC1	O14757	CHEK1	S354	R353Q	353	Missense	proximal	-1	no	10.381	10.396	EPSD	COSMIC	5.604	Up-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q86WB0	ZC3HC1	O14757	CHEK1	S354	S354C	354	Missense	central	0	yes	10.381	0.000	EPSD	COSMIC	5.604	Loss
CAMK_CAMKL_CHK1_CHEK1_ST	Q86WB0	ZC3HC1	O14757	CHEK1	S354	D356H	356	Missense	proximal	2	no	10.381	9.838	EPSD	COSMIC;GDSC;CCLE	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q86WB0	ZC3HC1	O14757	CHEK1	T379	P377T	377	Missense	proximal	-2	no	9.170	9.140	EPSD	COSMIC	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q86WB0	ZC3HC1	O14757	CHEK1	T379	P377Q	377	Missense	proximal	-2	no	9.170	9.031	EPSD	COSMIC	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q86WB0	ZC3HC1	O14757	CHEK1	T379	R376H	376	Missense	distal	-3	no	9.170	3.360	EPSD	COSMIC	5.604	Loss
CAMK_CAMKL_CHK1_CHEK1_ST	Q86WB0	ZC3HC1	O14757	CHEK1	T379	T372I	372	Missense	distal	-7	no	9.170	9.394	EPSD	COSMIC	5.604	Up-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q86WB0	ZC3HC1	O14757	CHEK1	S407	D412H	412	Missense	distal	5	no	13.059	12.885	EPSD	COSMIC	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q86WB0	ZC3HC1	O14757	CHEK1	S407	A400P	400	Missense	distal	-7	no	13.059	11.940	EPSD	COSMIC;GDSC	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q86WB0	ZC3HC1	O14757	CHEK1	S407	S408F	408	Missense	proximal	1	no	13.059	13.054	EPSD	COSMIC	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q86WB0	ZC3HC1	O14757	CHEK1	S407	R404C	404	Missense	distal	-3	no	13.059	4.968	EPSD	COSMIC	5.604	Loss
CAMK_CAMKL_CHK1_CHEK1_ST	Q86WB0	ZC3HC1	O14757	CHEK1	S471	Q470R	470	Missense	proximal	-1	no	8.256	8.241	EPSD	COSMIC	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	P08631	HCK	O14757	CHEK1	S181	S183Y	183	Missense	proximal	2	no	5.617	5.320	EPSD	COSMIC	5.604	Loss
CAMK_CAMKL_CHK1_CHEK1_ST	P08631	HCK	O14757	CHEK1	S181	D188E	188	Missense	distal	7	no	5.617	5.559	EPSD	COSMIC	5.604	Loss
CAMK_CAMKL_CHK1_CHEK1_ST	P08631	HCK	O14757	CHEK1	S181	D188N	188	Missense	distal	7	no	5.617	5.455	EPSD	COSMIC	5.604	Loss
CAMK_CAMKL_CHK1_CHEK1_ST	P08631	HCK	O14757	CHEK1	S296	G295E	295	Missense	proximal	-1	no	5.778	5.670	EPSD	COSMIC	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	P08631	HCK	O14757	CHEK1	S296	T291M	291	Missense	distal	-5	no	5.778	3.460	EPSD	COSMIC	5.604	Loss
CAMK_CAMKL_CHK1_CHEK1_ST	P08631	HCK	O14757	CHEK1	S296	V289L	289	Missense	distal	-7	no	5.778	5.100	EPSD	COSMIC	5.604	Loss
CAMK_CAMKL_CHK1_CHEK1_ST	P08631	HCK	O14757	CHEK1	S296	A301V	301	Missense	distal	5	no	5.778	5.674	EPSD	COSMIC	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	P49790	NUP153	O14757	CHEK1	S320	M318I	318	Missense	proximal	-2	no	7.054	7.040	EPSD	COSMIC;GDSC;CCLE	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	P49790	NUP153	O14757	CHEK1	S320	A325G	325	Missense	distal	5	no	7.054	6.844	EPSD	COSMIC	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	P49790	NUP153	O14757	CHEK1	S320	A323V	323	Missense	distal	3	no	7.054	7.298	EPSD	COSMIC;GDSC	5.604	Up-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	P49790	NUP153	O14757	CHEK1	S320	M318T	318	Missense	proximal	-2	no	7.054	7.166	EPSD	COSMIC	5.604	Up-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	P49790	NUP153	O14757	CHEK1	S330	A325G	325	Missense	distal	-5	no	5.272	8.046	EPSD;PhosphoSitePlus	COSMIC	5.604	Gain
CAMK_CAMKL_CHK1_CHEK1_ST	P49790	NUP153	O14757	CHEK1	S374	T377A	377	Missense	distal	3	no	6.002	6.239	EPSD	COSMIC	5.604	Up-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	P49790	NUP153	O14757	CHEK1	S660	S660L	660	Missense	central	0	yes	5.790	0.000	EPSD	COSMIC	5.604	Loss
CAMK_CAMKL_CHK1_CHEK1_ST	P49790	NUP153	O14757	CHEK1	S660	G653R	653	Missense	distal	-7	no	5.790	5.752	EPSD	COSMIC	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	P49790	NUP153	O14757	CHEK1	S660	S655N	655	Missense	distal	-5	no	5.790	6.283	EPSD	COSMIC	5.604	Up-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	P49790	NUP153	O14757	CHEK1	S660	C664R	664	Missense	distal	4	no	5.790	5.686	EPSD	COSMIC	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	P49790	NUP153	O14757	CHEK1	S1019	E1012Q	1012	Missense	distal	-7	no	9.747	9.522	EPSD	COSMIC;GDSC;CCLE	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	P49790	NUP153	O14757	CHEK1	S1019	S1018F	1018	Missense	proximal	-1	no	9.747	10.021	EPSD	COSMIC	5.604	Up-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q9NWH9	SLTM	O14757	CHEK1	S97	D101E	101	Missense	distal	4	no	5.727	5.636	EPSD	COSMIC	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q9NWH9	SLTM	O14757	CHEK1	S330	K326N	326	Missense	distal	-4	no	6.399	6.284	EPSD	COSMIC	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q9NWH9	SLTM	O14757	CHEK1	S330	S325C	325	Missense	distal	-5	no	6.399	5.932	EPSD	COSMIC	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q9NWH9	SLTM	O14757	CHEK1	S330	S325A	325	Missense	distal	-5	no	6.399	3.671	EPSD	COSMIC;GDSC;CCLE	5.604	Loss
CAMK_CAMKL_CHK1_CHEK1_ST	Q9NWH9	SLTM	O14757	CHEK1	S550	E545D	545	Missense	distal	-5	no	5.294	5.693	EPSD	COSMIC	5.604	Gain
CAMK_CAMKL_CHK1_CHEK1_ST	Q9NWH9	SLTM	O14757	CHEK1	S551	V558G	558	Missense	distal	7	no	11.796	11.766	EPSD	COSMIC	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q9NWH9	SLTM	O14757	CHEK1	S551	E545D	545	Missense	distal	-6	no	11.796	11.746	EPSD	COSMIC	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q9NWH9	SLTM	O14757	CHEK1	S551	S550T	550	Missense	proximal	-1	no	11.796	12.000	EPSD	COSMIC	5.604	Up-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q9NWH9	SLTM	O14757	CHEK1	S551	S551F	551	Missense	central	0	yes	11.796	0.000	EPSD	COSMIC	5.604	Loss
CAMK_CAMKL_CHK1_CHEK1_ST	Q9NWH9	SLTM	O14757	CHEK1	S882	R879G	879	Missense	distal	-3	no	6.683	-1.091	EPSD	COSMIC	5.604	Loss
CAMK_CAMKL_CHK1_CHEK1_ST	Q9NWH9	SLTM	O14757	CHEK1	S882	M889I	889	Missense	distal	7	no	6.683	6.407	EPSD	COSMIC	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q9NWH9	SLTM	O14757	CHEK1	S882	P877S	877	Missense	distal	-5	no	6.683	8.202	EPSD	COSMIC	5.604	Up-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q9NWH9	SLTM	O14757	CHEK1	S909	S904F	904	Missense	distal	-5	no	8.091	7.716	EPSD	COSMIC	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q9NWH9	SLTM	O14757	CHEK1	S909	G915A	915	Missense	distal	6	no	8.091	8.268	EPSD	COSMIC	5.604	Up-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q9NWH9	SLTM	O14757	CHEK1	S962	W968G	968	Missense	distal	6	no	9.658	9.316	EPSD	COSMIC	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q9NWH9	SLTM	O14757	CHEK1	S962	G963R	963	Missense	proximal	1	no	9.658	9.666	EPSD	COSMIC	5.604	Up-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q9NWH9	SLTM	O14757	CHEK1	S962	R956C	956	Missense	distal	-6	no	9.658	9.774	EPSD	COSMIC	5.604	Up-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q9NWH9	SLTM	O14757	CHEK1	S962	E955K	955	Missense	distal	-7	no	9.658	10.355	EPSD	COSMIC	5.604	Up-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	O15294	OGT	O14757	CHEK1	S20	Q22K	22	Missense	proximal	2	no	11.636	11.793	PhosphoSitePlus	COSMIC	5.604	Up-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	O15294	OGT	O14757	CHEK1	S491	A494T	494	Missense	distal	3	no	5.861	5.623	EPSD	COSMIC	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	O15294	OGT	O14757	CHEK1	S491	D495G	495	Missense	distal	4	no	5.861	5.877	EPSD	COSMIC	5.604	Up-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	O15294	OGT	O14757	CHEK1	T819	R825C	825	Missense	distal	6	no	8.146	8.440	EPSD	COSMIC	5.604	Up-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q8NG66	NEK11	O14757	CHEK1	S273	N269K	269	Missense	distal	-4	no	9.778	9.893	PhosphoSitePlus	COSMIC	5.604	Up-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q8NG66	NEK11	O14757	CHEK1	S273	M267I	267	Missense	distal	-6	no	9.778	9.715	PhosphoSitePlus	COSMIC	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q8NG66	NEK11	O14757	CHEK1	S334	T329S	329	Missense	distal	-5	no	9.919	8.787	EPSD	COSMIC	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q8NG66	NEK11	O14757	CHEK1	S334	M339T	339	Missense	distal	5	no	9.919	9.809	EPSD	COSMIC	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	P10636	MAPT	O14757	CHEK1	S113	I108V	108	Missense	distal	-5	no	5.761	4.316	EPSD	COSMIC	5.604	Loss
CAMK_CAMKL_CHK1_CHEK1_ST	P10636	MAPT	O14757	CHEK1	S113	G107R	107	Missense	distal	-6	no	5.761	5.644	EPSD	COSMIC	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	P10636	MAPT	O14757	CHEK1	T167	P160Q	160	Missense	distal	-7	no	7.796	8.464	EPSD	COSMIC	5.604	Up-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	P10636	MAPT	O14757	CHEK1	T167	A166V	166	Missense	proximal	-1	no	7.796	7.718	EPSD	COSMIC;CCLE	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	P10636	MAPT	O14757	CHEK1	T167	E165K	165	Missense	proximal	-2	no	7.796	7.653	EPSD	COSMIC	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	P10636	MAPT	O14757	CHEK1	T167	P160S	160	Missense	distal	-7	no	7.796	8.466	EPSD	COSMIC	5.604	Up-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	P10636	MAPT	O14757	CHEK1	T167	G172V	172	Missense	distal	5	no	7.796	7.902	EPSD	COSMIC	5.604	Up-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	P10636	MAPT	O14757	CHEK1	S171	A166V	166	Missense	distal	-5	no	5.554	7.993	EPSD	COSMIC;CCLE	5.604	Gain
CAMK_CAMKL_CHK1_CHEK1_ST	P10636	MAPT	O14757	CHEK1	S171	D177G	177	Missense	distal	6	no	5.554	5.950	EPSD	COSMIC	5.604	Gain
CAMK_CAMKL_CHK1_CHEK1_ST	P10636	MAPT	O14757	CHEK1	S214	E210Q	210	Missense	distal	-4	no	12.525	12.482	EPSD	COSMIC	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	P10636	MAPT	O14757	CHEK1	S214	G207E	207	Missense	distal	-7	no	12.525	12.970	EPSD	COSMIC	5.604	Up-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	P10636	MAPT	O14757	CHEK1	S341	A337T	337	Missense	distal	-4	no	10.855	10.425	EPSD	COSMIC	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	P10636	MAPT	O14757	CHEK1	S341	G343R	343	Missense	proximal	2	no	10.855	10.825	EPSD	COSMIC	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	P10636	MAPT	O14757	CHEK1	S341	D345G	345	Missense	distal	4	no	10.855	10.872	EPSD	COSMIC	5.604	Up-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	P10636	MAPT	O14757	CHEK1	S341	K347N	347	Missense	distal	6	no	10.855	10.990	EPSD	COSMIC	5.604	Up-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	P10636	MAPT	O14757	CHEK1	S369	V368I	368	Missense	proximal	-1	no	6.623	6.485	EPSD	COSMIC	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	P10636	MAPT	O14757	CHEK1	S369	R370W	370	Missense	proximal	1	no	6.623	6.593	EPSD	COSMIC	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	P10636	MAPT	O14757	CHEK1	T386	G385V	385	Missense	proximal	-1	no	7.562	7.638	EPSD	COSMIC	5.604	Up-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	P10636	MAPT	O14757	CHEK1	T386	T386I	386	Missense	central	0	yes	7.562	0.000	EPSD	COSMIC	5.604	Loss
CAMK_CAMKL_CHK1_CHEK1_ST	P10636	MAPT	O14757	CHEK1	T386	D389N	389	Missense	distal	3	no	7.562	6.845	EPSD	COSMIC;GDSC;CCLE	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	P10636	MAPT	O14757	CHEK1	S451	S447P	447	Missense	distal	-4	no	9.414	9.650	EPSD	COSMIC	5.604	Up-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	P10636	MAPT	O14757	CHEK1	S451	R448Q	448	Missense	distal	-3	no	9.414	2.207	EPSD	COSMIC	5.604	Loss
CAMK_CAMKL_CHK1_CHEK1_ST	P10636	MAPT	O14757	CHEK1	S502	P506S	506	Missense	distal	4	no	5.680	5.540	EPSD	COSMIC	5.604	Loss
CAMK_CAMKL_CHK1_CHEK1_ST	P10636	MAPT	O14757	CHEK1	S502	A495T	495	Missense	distal	-7	no	5.680	4.363	EPSD	COSMIC	5.604	Loss
CAMK_CAMKL_CHK1_CHEK1_ST	P10636	MAPT	O14757	CHEK1	S502	G509V	509	Missense	distal	7	no	5.680	5.710	EPSD	COSMIC	5.604	Up-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	P10636	MAPT	O14757	CHEK1	S502	P506L	506	Missense	distal	4	no	5.680	5.576	EPSD	COSMIC	5.604	Loss
CAMK_CAMKL_CHK1_CHEK1_ST	P10636	MAPT	O14757	CHEK1	T529	R526H	526	Missense	distal	-3	no	6.339	0.530	EPSD	COSMIC	5.604	Loss
CAMK_CAMKL_CHK1_CHEK1_ST	P10636	MAPT	O14757	CHEK1	T529	R528S	528	Missense	proximal	-1	no	6.339	6.178	EPSD	COSMIC	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	P10636	MAPT	O14757	CHEK1	T529	P530S	530	Missense	proximal	1	no	6.339	6.375	EPSD	COSMIC	5.604	Up-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	P10636	MAPT	O14757	CHEK1	T529	P536H	536	Missense	distal	7	no	6.339	6.083	EPSD	COSMIC	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	P10636	MAPT	O14757	CHEK1	T529	P535Q	535	Missense	distal	6	no	6.339	5.800	EPSD	COSMIC	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	P10636	MAPT	O14757	CHEK1	S531	R526H	526	Missense	distal	-5	no	7.782	5.316	EPSD	COSMIC	5.604	Loss
CAMK_CAMKL_CHK1_CHEK1_ST	P10636	MAPT	O14757	CHEK1	S531	R528S	528	Missense	distal	-3	no	7.782	-1.914	EPSD	COSMIC	5.604	Loss
CAMK_CAMKL_CHK1_CHEK1_ST	P10636	MAPT	O14757	CHEK1	S531	P530S	530	Missense	proximal	-1	no	7.782	7.335	EPSD	COSMIC	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	P10636	MAPT	O14757	CHEK1	S531	P536H	536	Missense	distal	5	no	7.782	7.776	EPSD	COSMIC	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	P10636	MAPT	O14757	CHEK1	S531	P535Q	535	Missense	distal	4	no	7.782	7.692	EPSD	COSMIC	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	P10636	MAPT	O14757	CHEK1	S554	P550S	550	Missense	distal	-4	no	6.234	5.997	EPSD	COSMIC	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	P10636	MAPT	O14757	CHEK1	S554	R559C	559	Missense	distal	5	no	6.234	5.990	EPSD	COSMIC	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	P10636	MAPT	O14757	CHEK1	S554	P553R	553	Missense	proximal	-1	no	6.234	5.948	EPSD	COSMIC	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	P10636	MAPT	O14757	CHEK1	S554	P553L	553	Missense	proximal	-1	no	6.234	6.047	EPSD	COSMIC	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	P10636	MAPT	O14757	CHEK1	S554	P549L	549	Missense	distal	-5	no	6.234	10.941	EPSD	COSMIC	5.604	Up-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	P10636	MAPT	O14757	CHEK1	S554	S555F	555	Missense	proximal	1	no	6.234	6.229	EPSD	COSMIC	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	P10636	MAPT	O14757	CHEK1	S554	P553Q	553	Missense	proximal	-1	no	6.234	5.963	EPSD	COSMIC	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	P10636	MAPT	O14757	CHEK1	T562	V565M	565	Missense	distal	3	no	9.518	9.092	EPSD	COSMIC	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	P10636	MAPT	O14757	CHEK1	T562	P566S	566	Missense	distal	4	no	9.518	9.378	EPSD	COSMIC	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	P10636	MAPT	O14757	CHEK1	T562	R559C	559	Missense	distal	-3	no	9.518	1.426	EPSD	COSMIC	5.604	Loss
CAMK_CAMKL_CHK1_CHEK1_ST	P10636	MAPT	O14757	CHEK1	T562	S555F	555	Missense	distal	-7	no	9.518	7.786	EPSD	COSMIC	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	P10636	MAPT	O14757	CHEK1	T562	P568S	568	Missense	distal	6	no	9.518	8.898	EPSD	COSMIC	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	P10636	MAPT	O14757	CHEK1	S579	T580N	580	Missense	proximal	1	no	6.137	6.126	EPSD	COSMIC	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	P10636	MAPT	O14757	CHEK1	S579	G578S	578	Missense	proximal	-1	no	6.137	5.958	EPSD	COSMIC	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	P10636	MAPT	O14757	CHEK1	S610	N613D	613	Missense	distal	3	no	5.724	6.440	EPSD	COSMIC	5.604	Up-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	P10636	MAPT	O14757	CHEK1	S610	C608W	608	Missense	proximal	-2	no	5.724	5.897	EPSD	COSMIC	5.604	Up-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	P10636	MAPT	O14757	CHEK1	S610	S610L	610	Missense	central	0	yes	5.724	0.000	EPSD	COSMIC	5.604	Loss
CAMK_CAMKL_CHK1_CHEK1_ST	P10636	MAPT	O14757	CHEK1	S637	S633N	633	Missense	distal	-4	no	7.829	8.123	EPSD	COSMIC	5.604	Up-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	P10636	MAPT	O14757	CHEK1	S637	S633I	633	Missense	distal	-4	no	7.829	7.849	EPSD	COSMIC	5.604	Up-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	P10636	MAPT	O14757	CHEK1	S641	H647Y	647	Missense	distal	6	no	9.317	9.683	EPSD	COSMIC	5.604	Up-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	P10636	MAPT	O14757	CHEK1	S669	S669L	669	Missense	central	0	yes	8.551	0.000	EPSD	COSMIC	5.604	Loss
CAMK_CAMKL_CHK1_CHEK1_ST	P10636	MAPT	O14757	CHEK1	S669	R666K	666	Missense	distal	-3	no	8.551	4.726	EPSD	COSMIC	5.604	Loss
CAMK_CAMKL_CHK1_CHEK1_ST	P10636	MAPT	O14757	CHEK1	S669	D662G	662	Missense	distal	-7	no	8.551	8.560	EPSD	COSMIC	5.604	Up-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	P10636	MAPT	O14757	CHEK1	S669	S673F	673	Missense	distal	4	no	8.551	8.649	EPSD	COSMIC	5.604	Up-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	P10636	MAPT	O14757	CHEK1	S669	K670N	670	Missense	proximal	1	no	8.551	8.522	EPSD	COSMIC	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	P10636	MAPT	O14757	CHEK1	S669	K664N	664	Missense	distal	-5	no	8.551	7.657	EPSD	COSMIC	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	P10636	MAPT	O14757	CHEK1	S669	L674Q	674	Missense	distal	5	no	8.551	8.767	EPSD	COSMIC	5.604	Up-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	P10636	MAPT	O14757	CHEK1	S673	R666K	666	Missense	distal	-7	no	5.292	6.472	EPSD	COSMIC	5.604	Gain
CAMK_CAMKL_CHK1_CHEK1_ST	P10636	MAPT	O14757	CHEK1	T690	R696H	696	Missense	distal	6	no	5.675	5.963	EPSD	COSMIC	5.604	Up-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	P10636	MAPT	O14757	CHEK1	T690	G683R	683	Missense	distal	-7	no	5.675	5.637	EPSD	COSMIC;CCLE	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	P10636	MAPT	O14757	CHEK1	T690	G683E	683	Missense	distal	-7	no	5.675	6.120	EPSD	COSMIC	5.604	Up-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	P10636	MAPT	O14757	CHEK1	T690	R696C	696	Missense	distal	6	no	5.675	5.969	EPSD	COSMIC	5.604	Up-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	P10636	MAPT	O14757	CHEK1	T690	G684E	684	Missense	distal	-6	no	5.675	5.515	EPSD	COSMIC	5.604	Loss
CAMK_CAMKL_CHK1_CHEK1_ST	P10636	MAPT	O14757	CHEK1	S726	G732S	732	Missense	distal	6	no	10.748	10.535	EPSD	COSMIC	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	P10636	MAPT	O14757	CHEK1	S726	G732C	732	Missense	distal	6	no	10.748	10.917	EPSD	COSMIC	5.604	Up-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	P10636	MAPT	O14757	CHEK1	S726	R723W	723	Missense	distal	-3	no	10.748	-22.856	EPSD	COSMIC	5.604	Loss
CAMK_CAMKL_CHK1_CHEK1_ST	P10636	MAPT	O14757	CHEK1	S726	V728M	728	Missense	proximal	2	no	10.748	10.927	EPSD	COSMIC	5.604	Up-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	P10636	MAPT	O14757	CHEK1	S726	V728A	728	Missense	proximal	2	no	10.748	11.310	EPSD	COSMIC	5.604	Up-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q04837	SSBP1	O14757	CHEK1	S67	G68A	68	Missense	proximal	1	no	8.214	8.215	PhosphoSitePlus	COSMIC	5.604	Up-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q14676	MDC1	O14757	CHEK1	S108	P103L	103	Missense	distal	-5	no	2.955	7.662	EPSD	COSMIC	5.604	Gain
CAMK_CAMKL_CHK1_CHEK1_ST	Q14676	MDC1	O14757	CHEK1	S112	P109A	109	Missense	distal	-3	no	7.587	8.012	EPSD	COSMIC	5.604	Up-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q14676	MDC1	O14757	CHEK1	S112	R116S	116	Missense	distal	4	no	7.587	7.537	EPSD	COSMIC	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q14676	MDC1	O14757	CHEK1	S112	H113P	113	Missense	proximal	1	no	7.587	7.590	EPSD	COSMIC	5.604	Up-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q14676	MDC1	O14757	CHEK1	S112	E119G	119	Missense	distal	7	no	7.587	7.352	EPSD	COSMIC	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q14676	MDC1	O14757	CHEK1	S168	E170D	170	Missense	proximal	2	no	6.964	6.881	EPSD	COSMIC	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q14676	MDC1	O14757	CHEK1	S168	D173N	173	Missense	distal	5	no	6.964	6.875	EPSD	COSMIC	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q14676	MDC1	O14757	CHEK1	T378	Q373L	373	Missense	distal	-5	no	3.926	7.299	EPSD	COSMIC	5.604	Gain
CAMK_CAMKL_CHK1_CHEK1_ST	Q14676	MDC1	O14757	CHEK1	T447	R444Q	444	Missense	distal	-3	no	12.033	4.826	EPSD	COSMIC	5.604	Loss
CAMK_CAMKL_CHK1_CHEK1_ST	Q14676	MDC1	O14757	CHEK1	T447	T448I	448	Missense	proximal	1	no	12.033	11.990	EPSD	COSMIC	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q14676	MDC1	O14757	CHEK1	S453	T448I	448	Missense	distal	-5	no	6.224	6.249	EPSD	COSMIC	5.604	Up-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q14676	MDC1	O14757	CHEK1	S485	F492V	492	Missense	distal	7	no	13.565	14.123	EPSD	COSMIC	5.604	Up-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q14676	MDC1	O14757	CHEK1	S485	E486K	486	Missense	proximal	1	no	13.565	13.491	EPSD	COSMIC	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q14676	MDC1	O14757	CHEK1	S874	S874C	874	Missense	central	0	yes	7.950	0.000	EPSD	COSMIC	5.604	Loss
CAMK_CAMKL_CHK1_CHEK1_ST	Q14676	MDC1	O14757	CHEK1	S874	R871K	871	Missense	distal	-3	no	7.950	4.125	EPSD	COSMIC	5.604	Loss
CAMK_CAMKL_CHK1_CHEK1_ST	Q14676	MDC1	O14757	CHEK1	S874	G878V	878	Missense	distal	4	no	7.950	7.994	EPSD	COSMIC	5.604	Up-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q14676	MDC1	O14757	CHEK1	S981	P983S	983	Missense	proximal	2	no	5.787	5.864	EPSD	COSMIC	5.604	Up-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q14676	MDC1	O14757	CHEK1	S981	S986F	986	Missense	distal	5	no	5.787	5.462	EPSD	COSMIC	5.604	Loss
CAMK_CAMKL_CHK1_CHEK1_ST	Q14676	MDC1	O14757	CHEK1	S981	P985L	985	Missense	distal	4	no	5.787	5.683	EPSD	COSMIC	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q14676	MDC1	O14757	CHEK1	S981	G978R	978	Missense	distal	-3	no	5.787	13.561	EPSD	COSMIC	5.604	Up-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q14676	MDC1	O14757	CHEK1	S981	S981A	981	Missense	central	0	yes	5.787	0.000	EPSD	COSMIC	5.604	Loss
CAMK_CAMKL_CHK1_CHEK1_ST	Q14676	MDC1	O14757	CHEK1	S1095	P1090L	1090	Missense	distal	-5	no	1.064	5.771	EPSD	COSMIC	5.604	Gain
CAMK_CAMKL_CHK1_CHEK1_ST	Q14676	MDC1	O14757	CHEK1	S1122	P1119R	1119	Missense	distal	-3	no	-0.518	6.619	EPSD	COSMIC	5.604	Gain
CAMK_CAMKL_CHK1_CHEK1_ST	Q14676	MDC1	O14757	CHEK1	T1150	A1145T	1145	Missense	distal	-5	no	3.461	7.322	EPSD	COSMIC	5.604	Gain
CAMK_CAMKL_CHK1_CHEK1_ST	Q14676	MDC1	O14757	CHEK1	T1220	R1217Q	1217	Missense	distal	-3	no	8.632	1.425	EPSD	COSMIC	5.604	Loss
CAMK_CAMKL_CHK1_CHEK1_ST	Q14676	MDC1	O14757	CHEK1	T1220	T1213A	1213	Missense	distal	-7	no	8.632	9.949	EPSD	COSMIC	5.604	Up-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q14676	MDC1	O14757	CHEK1	T1220	T1215I	1215	Missense	distal	-5	no	8.632	8.657	EPSD	COSMIC	5.604	Up-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q14676	MDC1	O14757	CHEK1	T1254	Q1251R	1251	Missense	distal	-3	no	1.339	8.546	EPSD	COSMIC	5.604	Gain
CAMK_CAMKL_CHK1_CHEK1_ST	Q14676	MDC1	O14757	CHEK1	T1295	T1302N	1302	Missense	distal	7	no	8.594	8.890	EPSD	COSMIC	5.604	Up-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q14676	MDC1	O14757	CHEK1	T1295	P1300L	1300	Missense	distal	5	no	8.594	8.432	EPSD	COSMIC	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q14676	MDC1	O14757	CHEK1	T1302	R1308W	1308	Missense	distal	6	no	8.841	9.308	EPSD	COSMIC	5.604	Up-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q14676	MDC1	O14757	CHEK1	T1302	T1302N	1302	Missense	central	0	yes	8.841	0.000	EPSD	COSMIC	5.604	Loss
CAMK_CAMKL_CHK1_CHEK1_ST	Q14676	MDC1	O14757	CHEK1	T1302	P1300L	1300	Missense	proximal	-2	no	8.841	8.662	EPSD	COSMIC	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q14676	MDC1	O14757	CHEK1	T1314	S1318F	1318	Missense	distal	4	no	8.538	8.636	EPSD	COSMIC	5.604	Up-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q14676	MDC1	O14757	CHEK1	T1314	R1308W	1308	Missense	distal	-6	no	8.538	8.858	EPSD	COSMIC	5.604	Up-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q14676	MDC1	O14757	CHEK1	T1314	R1311M	1311	Missense	distal	-3	no	8.538	3.390	EPSD	COSMIC	5.604	Loss
CAMK_CAMKL_CHK1_CHEK1_ST	Q14676	MDC1	O14757	CHEK1	T1314	M1316V	1316	Missense	proximal	2	no	8.538	8.359	EPSD	COSMIC	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q14676	MDC1	O14757	CHEK1	T1314	S1318A	1318	Missense	distal	4	no	8.538	8.732	EPSD	COSMIC	5.604	Up-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q14676	MDC1	O14757	CHEK1	T1314	M1316T	1316	Missense	proximal	2	no	8.538	8.073	EPSD	COSMIC	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q14676	MDC1	O14757	CHEK1	T1343	Q1340R	1340	Missense	distal	-3	no	1.534	8.741	EPSD	COSMIC	5.604	Gain
CAMK_CAMKL_CHK1_CHEK1_ST	Q14676	MDC1	O14757	CHEK1	T1418	E1415K	1415	Missense	distal	-3	no	4.807	8.070	EPSD	COSMIC	5.604	Gain
CAMK_CAMKL_CHK1_CHEK1_ST	Q14676	MDC1	O14757	CHEK1	T1560	A1555T	1555	Missense	distal	-5	no	3.924	7.785	EPSD	COSMIC	5.604	Gain
CAMK_CAMKL_CHK1_CHEK1_ST	Q14676	MDC1	O14757	CHEK1	T1688	S1686F	1686	Missense	proximal	-2	no	7.838	8.128	EPSD	COSMIC	5.604	Up-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q14676	MDC1	O14757	CHEK1	T1688	P1693L	1693	Missense	distal	5	no	7.838	7.677	EPSD	COSMIC	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q14676	MDC1	O14757	CHEK1	T1688	T1683A	1683	Missense	distal	-5	no	7.838	3.978	EPSD	COSMIC	5.604	Loss
CAMK_CAMKL_CHK1_CHEK1_ST	Q14676	MDC1	O14757	CHEK1	T1688	R1690K	1690	Missense	proximal	2	no	7.838	8.524	EPSD	COSMIC;GDSC;CCLE	5.604	Up-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q14676	MDC1	O14757	CHEK1	S1814	R1811C	1811	Missense	distal	-3	no	8.693	0.601	EPSD	COSMIC	5.604	Loss
CAMK_CAMKL_CHK1_CHEK1_ST	Q14676	MDC1	O14757	CHEK1	S1878	E1872Q	1872	Missense	distal	-6	no	7.677	7.801	EPSD	COSMIC	5.604	Up-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q14676	MDC1	O14757	CHEK1	S1878	R1882Q	1882	Missense	distal	4	no	7.677	7.676	EPSD	COSMIC	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q14676	MDC1	O14757	CHEK1	S1878	I1876T	1876	Missense	proximal	-2	no	7.677	7.803	EPSD	COSMIC	5.604	Up-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q14676	MDC1	O14757	CHEK1	S1878	E1872K	1872	Missense	distal	-6	no	7.677	7.708	EPSD	COSMIC	5.604	Up-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q14676	MDC1	O14757	CHEK1	S1878	R1875K	1875	Missense	distal	-3	no	7.677	3.851	EPSD	COSMIC	5.604	Loss
CAMK_CAMKL_CHK1_CHEK1_ST	P52292	KPNA2	O14757	CHEK1	T25	D23Y	23	Missense	proximal	-2	no	6.135	6.200	EPSD	COSMIC;CCLE	5.604	Up-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	P52292	KPNA2	O14757	CHEK1	T25	R30C	30	Missense	distal	5	no	6.135	5.891	EPSD	COSMIC	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	P52292	KPNA2	O14757	CHEK1	S54	S55L	55	Missense	proximal	1	no	11.941	11.932	PhosphoSitePlus	COSMIC	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	P52292	KPNA2	O14757	CHEK1	T230	R227H	227	Missense	distal	-3	no	5.966	0.157	EPSD	COSMIC	5.604	Loss
CAMK_CAMKL_CHK1_CHEK1_ST	P25205	MCM3	O14757	CHEK1	S112	R114Q	114	Missense	proximal	2	no	5.335	5.864	EPSD	COSMIC	5.604	Gain
CAMK_CAMKL_CHK1_CHEK1_ST	P25205	MCM3	O14757	CHEK1	S160	T163I	163	Missense	distal	3	no	12.830	12.598	PhosphoSitePlus	COSMIC	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	P25205	MCM3	O14757	CHEK1	S269	A262T	262	Missense	distal	-7	no	8.468	7.151	EPSD	COSMIC	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	P25205	MCM3	O14757	CHEK1	S269	K270N	270	Missense	proximal	1	no	8.468	8.439	EPSD	COSMIC	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	P25205	MCM3	O14757	CHEK1	S269	N264K	264	Missense	distal	-5	no	8.468	9.361	EPSD	COSMIC	5.604	Up-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	P25205	MCM3	O14757	CHEK1	S269	A272V	272	Missense	distal	3	no	8.468	8.712	EPSD	COSMIC	5.604	Up-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	P25205	MCM3	O14757	CHEK1	S269	K270T	270	Missense	proximal	1	no	8.468	8.449	EPSD	COSMIC	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	P25205	MCM3	O14757	CHEK1	S269	A272T	272	Missense	distal	3	no	8.468	8.230	EPSD	COSMIC	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	P25205	MCM3	O14757	CHEK1	S275	K270N	270	Missense	distal	-5	no	6.935	6.042	EPSD	COSMIC	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	P25205	MCM3	O14757	CHEK1	S275	E279K	279	Missense	distal	4	no	6.935	6.929	EPSD	COSMIC	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	P25205	MCM3	O14757	CHEK1	S275	A272V	272	Missense	distal	-3	no	6.935	5.184	EPSD	COSMIC	5.604	Loss
CAMK_CAMKL_CHK1_CHEK1_ST	P25205	MCM3	O14757	CHEK1	S275	K270T	270	Missense	distal	-5	no	6.935	6.681	EPSD	COSMIC	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	P25205	MCM3	O14757	CHEK1	S275	A278T	278	Missense	distal	3	no	6.935	6.698	EPSD	COSMIC	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	P25205	MCM3	O14757	CHEK1	S275	A282V	282	Missense	distal	7	no	6.935	7.015	EPSD	COSMIC	5.604	Up-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	P25205	MCM3	O14757	CHEK1	S275	A272T	272	Missense	distal	-3	no	6.935	-6.922	EPSD	COSMIC	5.604	Loss
CAMK_CAMKL_CHK1_CHEK1_ST	P25205	MCM3	O14757	CHEK1	S277	A272T	272	Missense	distal	-5	no	2.301	6.162	EPSD	COSMIC	5.604	Gain
CAMK_CAMKL_CHK1_CHEK1_ST	P25205	MCM3	O14757	CHEK1	S292	S292F	292	Missense	central	0	yes	5.857	0.000	EPSD	COSMIC	5.604	Loss
CAMK_CAMKL_CHK1_CHEK1_ST	P25205	MCM3	O14757	CHEK1	S292	T290N	290	Missense	proximal	-2	no	5.857	5.792	EPSD	COSMIC	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	P25205	MCM3	O14757	CHEK1	S292	L299P	299	Missense	distal	7	no	5.857	5.920	EPSD	COSMIC	5.604	Up-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	P25205	MCM3	O14757	CHEK1	S292	T290S	290	Missense	proximal	-2	no	5.857	5.603	EPSD	COSMIC	5.604	Loss
CAMK_CAMKL_CHK1_CHEK1_ST	P25205	MCM3	O14757	CHEK1	S374	S374F	374	Missense	central	0	yes	10.691	0.000	EPSD	COSMIC	5.604	Loss
CAMK_CAMKL_CHK1_CHEK1_ST	P25205	MCM3	O14757	CHEK1	S374	T379R	379	Missense	distal	5	no	10.691	10.810	EPSD	COSMIC	5.604	Up-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	P25205	MCM3	O14757	CHEK1	T383	T384A	384	Missense	proximal	1	no	7.953	7.964	EPSD	COSMIC	5.604	Up-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	P25205	MCM3	O14757	CHEK1	T383	T379R	379	Missense	distal	-4	no	7.953	8.312	EPSD	COSMIC	5.604	Up-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	P25205	MCM3	O14757	CHEK1	T384	T384A	384	Missense	central	0	yes	5.864	0.000	EPSD	COSMIC	5.604	Loss
CAMK_CAMKL_CHK1_CHEK1_ST	P25205	MCM3	O14757	CHEK1	T384	R391H	391	Missense	distal	7	no	5.864	5.571	EPSD	COSMIC	5.604	Loss
CAMK_CAMKL_CHK1_CHEK1_ST	P25205	MCM3	O14757	CHEK1	T384	T379R	379	Missense	distal	-5	no	5.864	4.943	EPSD	COSMIC	5.604	Loss
CAMK_CAMKL_CHK1_CHEK1_ST	P25205	MCM3	O14757	CHEK1	S564	K557E	557	Missense	distal	-7	no	6.591	5.894	EPSD	COSMIC;CCLE	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	P25205	MCM3	O14757	CHEK1	S564	K569N	569	Missense	distal	5	no	6.591	6.568	EPSD	COSMIC	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	P25205	MCM3	O14757	CHEK1	S599	R596H	596	Missense	distal	-3	no	8.306	2.497	EPSD	COSMIC	5.604	Loss
CAMK_CAMKL_CHK1_CHEK1_ST	P25205	MCM3	O14757	CHEK1	S599	M603L	603	Missense	distal	4	no	8.306	8.232	EPSD	COSMIC	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	P25205	MCM3	O14757	CHEK1	S668	K663Q	663	Missense	distal	-5	no	11.313	9.741	EPSD	COSMIC	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	P25205	MCM3	O14757	CHEK1	S668	R667Q	667	Missense	proximal	-1	no	11.313	11.328	EPSD	COSMIC	5.604	Up-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	P25205	MCM3	O14757	CHEK1	S668	E673K	673	Missense	distal	5	no	11.313	11.248	EPSD	COSMIC	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	P25205	MCM3	O14757	CHEK1	S668	R664C	664	Missense	distal	-4	no	11.313	10.939	EPSD	COSMIC	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	P25205	MCM3	O14757	CHEK1	S668	E669K	669	Missense	proximal	1	no	11.313	11.239	EPSD	COSMIC	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	P25205	MCM3	O14757	CHEK1	S672	E669K	669	Missense	distal	-3	no	5.415	8.677	EPSD	COSMIC	5.604	Gain
CAMK_CAMKL_CHK1_CHEK1_ST	P25205	MCM3	O14757	CHEK1	T694	R695H	695	Missense	proximal	1	no	6.911	6.846	EPSD	COSMIC	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	P25205	MCM3	O14757	CHEK1	T694	K688N	688	Missense	distal	-6	no	6.911	7.043	EPSD	COSMIC	5.604	Up-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	P25205	MCM3	O14757	CHEK1	T694	D701N	701	Missense	distal	7	no	6.911	6.750	EPSD	COSMIC	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	P25205	MCM3	O14757	CHEK1	T694	R695L	695	Missense	proximal	1	no	6.911	6.877	EPSD	COSMIC	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	P25205	MCM3	O14757	CHEK1	T694	R695C	695	Missense	proximal	1	no	6.911	6.901	EPSD	COSMIC	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	P25205	MCM3	O14757	CHEK1	T694	D698N	698	Missense	distal	4	no	6.911	6.881	EPSD	COSMIC	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	O95707	POP4	O14757	CHEK1	S10	A8T	8	Missense	proximal	-2	no	6.269	6.409	PhosphoSitePlus	COSMIC	5.604	Up-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	O95707	POP4	O14757	CHEK1	S10	S17F	17	Missense	distal	7	no	6.269	5.839	PhosphoSitePlus	COSMIC	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	O95707	POP4	O14757	CHEK1	S17	S17F	17	Missense	central	0	yes	6.378	0.000	EPSD	COSMIC	5.604	Loss
CAMK_CAMKL_CHK1_CHEK1_ST	P35612	ADD2	O14757	CHEK1	S396	P401S	401	Missense	distal	5	no	10.020	10.102	EPSD	COSMIC	5.604	Up-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	P35612	ADD2	O14757	CHEK1	S396	T403M	403	Missense	distal	7	no	10.020	10.072	EPSD	COSMIC;GDSC;CCLE	5.604	Up-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	P35612	ADD2	O14757	CHEK1	S396	S396N	396	Missense	central	0	yes	10.020	0.000	EPSD	COSMIC	5.604	Loss
CAMK_CAMKL_CHK1_CHEK1_ST	P35612	ADD2	O14757	CHEK1	S532	S528T	528	Missense	distal	-4	no	10.836	10.785	EPSD	COSMIC	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	P35612	ADD2	O14757	CHEK1	S667	L662F	662	Missense	distal	-5	no	6.906	3.343	EPSD	COSMIC	5.604	Loss
CAMK_CAMKL_CHK1_CHEK1_ST	P35612	ADD2	O14757	CHEK1	S667	S663N	663	Missense	distal	-4	no	6.906	7.201	EPSD	COSMIC	5.604	Up-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	P35612	ADD2	O14757	CHEK1	S703	P698L	698	Missense	distal	-5	no	3.754	8.461	EPSD	COSMIC	5.604	Gain
CAMK_CAMKL_CHK1_CHEK1_ST	P35612	ADD2	O14757	CHEK1	T711	P712S	712	Missense	proximal	1	no	6.300	6.337	EPSD	COSMIC	5.604	Up-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	P35612	ADD2	O14757	CHEK1	T711	F709Y	709	Missense	proximal	-2	no	6.300	6.123	EPSD	COSMIC	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	P35612	ADD2	O14757	CHEK1	T711	S718R	718	Missense	distal	7	no	6.300	6.393	EPSD	COSMIC;GDSC;CCLE	5.604	Up-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	P35612	ADD2	O14757	CHEK1	T711	F709L	709	Missense	proximal	-2	no	6.300	6.116	EPSD	COSMIC	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	P35612	ADD2	O14757	CHEK1	S713	P712S	712	Missense	proximal	-1	no	8.097	7.650	PhosphoSitePlus	COSMIC	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	P35612	ADD2	O14757	CHEK1	S713	F709Y	709	Missense	distal	-4	no	8.097	8.163	PhosphoSitePlus	COSMIC	5.604	Up-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	P35612	ADD2	O14757	CHEK1	S713	S718R	718	Missense	distal	5	no	8.097	7.994	PhosphoSitePlus	COSMIC;GDSC;CCLE	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	P35612	ADD2	O14757	CHEK1	S713	F709L	709	Missense	distal	-4	no	8.097	8.392	PhosphoSitePlus	COSMIC	5.604	Up-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q8IY67	RAVER1	O14757	CHEK1	T214	G211R	211	Missense	distal	-3	no	-1.630	6.145	EPSD	COSMIC	5.604	Gain
CAMK_CAMKL_CHK1_CHEK1_ST	Q8IY67	RAVER1	O14757	CHEK1	S243	A241V	241	Missense	proximal	-2	no	11.519	11.596	EPSD	COSMIC	5.604	Up-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q8IY67	RAVER1	O14757	CHEK1	S243	D236N	236	Missense	distal	-7	no	11.519	11.211	EPSD	COSMIC	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q8IY67	RAVER1	O14757	CHEK1	S243	R240Q	240	Missense	distal	-3	no	11.519	4.312	EPSD	COSMIC	5.604	Loss
CAMK_CAMKL_CHK1_CHEK1_ST	Q8IY67	RAVER1	O14757	CHEK1	S243	R240W	240	Missense	distal	-3	no	11.519	-22.084	EPSD	COSMIC	5.604	Loss
CAMK_CAMKL_CHK1_CHEK1_ST	Q8IY67	RAVER1	O14757	CHEK1	S243	F250L	250	Missense	distal	7	no	11.519	11.941	EPSD	COSMIC	5.604	Up-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q8IY67	RAVER1	O14757	CHEK1	S485	S485P	485	Missense	central	0	yes	6.939	0.000	EPSD	COSMIC	5.604	Loss
CAMK_CAMKL_CHK1_CHEK1_ST	Q8IY67	RAVER1	O14757	CHEK1	S583	P580R	580	Missense	distal	-3	no	4.586	11.723	EPSD	COSMIC	5.604	Gain
CAMK_CAMKL_CHK1_CHEK1_ST	P35611	ADD1	O14757	CHEK1	S355	G361V	361	Missense	distal	6	no	7.969	8.033	EPSD	COSMIC	5.604	Up-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	P35611	ADD1	O14757	CHEK1	S408	D409N	409	Missense	proximal	1	no	8.571	8.463	EPSD	COSMIC;GDSC;CCLE	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	P35611	ADD1	O14757	CHEK1	T470	G477E	477	Missense	distal	7	no	5.527	5.762	EPSD	COSMIC	5.604	Gain
CAMK_CAMKL_CHK1_CHEK1_ST	P35611	ADD1	O14757	CHEK1	T482	G477E	477	Missense	distal	-5	no	8.115	6.894	EPSD	COSMIC	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	P35611	ADD1	O14757	CHEK1	S645	P639H	639	Missense	distal	-6	no	5.682	5.614	EPSD	COSMIC	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	P35611	ADD1	O14757	CHEK1	S645	E651D	651	Missense	distal	6	no	5.682	5.768	EPSD	COSMIC	5.604	Up-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	P35611	ADD1	O14757	CHEK1	S669	P670F	670	Missense	proximal	1	no	6.914	6.946	EPSD	COSMIC	5.604	Up-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	P35611	ADD1	O14757	CHEK1	S726	S726L	726	Missense	central	0	yes	11.735	0.000	PhosphoSitePlus	COSMIC	5.604	Loss
CAMK_CAMKL_CHK1_CHEK1_ST	Q6UB98	ANKRD12	O14757	CHEK1	S149	S149N	149	Missense	central	0	yes	9.906	0.000	EPSD	COSMIC	5.604	Loss
CAMK_CAMKL_CHK1_CHEK1_ST	Q6UB98	ANKRD12	O14757	CHEK1	S526	T531N	531	Missense	distal	5	no	7.615	7.835	EPSD	COSMIC	5.604	Up-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q6UB98	ANKRD12	O14757	CHEK1	S526	R522S	522	Missense	distal	-4	no	7.615	7.307	EPSD	COSMIC	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q6UB98	ANKRD12	O14757	CHEK1	S555	E552K	552	Missense	distal	-3	no	2.916	6.179	EPSD	COSMIC	5.604	Gain
CAMK_CAMKL_CHK1_CHEK1_ST	Q6UB98	ANKRD12	O14757	CHEK1	S903	D898G	898	Missense	distal	-5	no	7.850	8.671	EPSD	COSMIC;GDSC;CCLE	5.604	Up-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q6UB98	ANKRD12	O14757	CHEK1	S903	E905K	905	Missense	proximal	2	no	7.850	7.891	EPSD	COSMIC	5.604	Up-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q6UB98	ANKRD12	O14757	CHEK1	S903	R909M	909	Missense	distal	6	no	7.850	8.163	EPSD	COSMIC;GDSC;CCLE	5.604	Up-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q6UB98	ANKRD12	O14757	CHEK1	S1047	S1041N	1041	Missense	distal	-6	no	10.093	10.134	EPSD	COSMIC;GDSC;CCLE	5.604	Up-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q6UB98	ANKRD12	O14757	CHEK1	S1047	D1050A	1050	Missense	distal	3	no	10.093	8.630	EPSD	COSMIC	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q6UB98	ANKRD12	O14757	CHEK1	S1056	D1050A	1050	Missense	distal	-6	no	6.113	6.159	EPSD	COSMIC	5.604	Up-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q6UB98	ANKRD12	O14757	CHEK1	S1085	S1085N	1085	Missense	central	0	yes	8.603	0.000	EPSD	COSMIC	5.604	Loss
CAMK_CAMKL_CHK1_CHEK1_ST	Q6UB98	ANKRD12	O14757	CHEK1	S1143	R1140I	1140	Missense	distal	-3	no	14.270	5.512	EPSD	COSMIC	5.604	Loss
CAMK_CAMKL_CHK1_CHEK1_ST	Q6UB98	ANKRD12	O14757	CHEK1	S1166	R1163I	1163	Missense	distal	-3	no	8.505	-0.253	EPSD	COSMIC	5.604	Loss
CAMK_CAMKL_CHK1_CHEK1_ST	Q6UB98	ANKRD12	O14757	CHEK1	S1290	K1295I	1295	Missense	distal	5	no	7.393	7.229	EPSD	COSMIC	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q6UB98	ANKRD12	O14757	CHEK1	S1290	S1288R	1288	Missense	proximal	-2	no	7.393	7.492	EPSD	COSMIC	5.604	Up-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q6UB98	ANKRD12	O14757	CHEK1	S1311	R1309S	1309	Missense	proximal	-2	no	6.033	5.934	EPSD	COSMIC	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q6UB98	ANKRD12	O14757	CHEK1	S1311	R1308Q	1308	Missense	distal	-3	no	6.033	-1.174	EPSD	COSMIC;GDSC;CCLE	5.604	Loss
CAMK_CAMKL_CHK1_CHEK1_ST	Q6UB98	ANKRD12	O14757	CHEK1	S1790	R1791H	1791	Missense	proximal	1	no	9.650	9.585	EPSD	COSMIC;GDSC;CCLE	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q6UB98	ANKRD12	O14757	CHEK1	S1790	V1792I	1792	Missense	proximal	2	no	9.650	9.250	EPSD	COSMIC;GDSC;CCLE	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q6UB98	ANKRD12	O14757	CHEK1	S1790	R1785L	1785	Missense	distal	-5	no	9.650	12.627	EPSD	COSMIC	5.604	Up-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q9H8N7	ZNF395	O14757	CHEK1	S13	G10R	10	Missense	distal	-3	no	0.241	8.016	EPSD	COSMIC;GDSC;CCLE	5.604	Gain
CAMK_CAMKL_CHK1_CHEK1_ST	Q9H8N7	ZNF395	O14757	CHEK1	S275	C282Y	282	Missense	distal	7	no	8.740	8.538	EPSD	COSMIC	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q9H8N7	ZNF395	O14757	CHEK1	S447	S447L	447	Missense	central	0	yes	8.186	0.000	PhosphoSitePlus	COSMIC	5.604	Loss
CAMK_CAMKL_CHK1_CHEK1_ST	Q9H8N7	ZNF395	O14757	CHEK1	S449	S447L	447	Missense	proximal	-2	no	10.362	10.467	EPSD	COSMIC	5.604	Up-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q9H8N7	ZNF395	O14757	CHEK1	S474	Q473H	473	Missense	proximal	-1	no	8.825	8.935	EPSD	COSMIC	5.604	Up-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q9H8N7	ZNF395	O14757	CHEK1	S474	A476T	476	Missense	proximal	2	no	8.825	7.977	EPSD	COSMIC	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	P12956	XRCC6	O14757	CHEK1	S53	M48V	48	Missense	distal	-5	no	5.603	6.500	EPSD	COSMIC	5.604	Gain
CAMK_CAMKL_CHK1_CHEK1_ST	P12956	XRCC6	O14757	CHEK1	T170	M167K	167	Missense	distal	-3	no	8.495	9.819	EPSD	COSMIC	5.604	Up-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	P12956	XRCC6	O14757	CHEK1	T334	I328V	328	Missense	distal	-6	no	6.400	6.413	EPSD	COSMIC	5.604	Up-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	P12956	XRCC6	O14757	CHEK1	T334	F340L	340	Missense	distal	6	no	6.400	6.407	EPSD	COSMIC	5.604	Up-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	P12956	XRCC6	O14757	CHEK1	T334	E330K	330	Missense	distal	-4	no	6.400	6.298	EPSD	COSMIC	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	P12956	XRCC6	O14757	CHEK1	T334	R339Q	339	Missense	distal	5	no	6.400	6.475	EPSD	COSMIC;CCLE	5.604	Up-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	P12956	XRCC6	O14757	CHEK1	S477	R470C	470	Missense	distal	-7	no	12.198	11.471	PhosphoSitePlus	COSMIC	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	P12956	XRCC6	O14757	CHEK1	S477	P481S	481	Missense	distal	4	no	12.198	12.058	PhosphoSitePlus	COSMIC	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q13043	STK4	O14757	CHEK1	T120	R115L	115	Missense	distal	-5	no	8.540	11.517	EPSD	COSMIC;GDSC;CCLE	5.604	Up-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q13043	STK4	O14757	CHEK1	T120	E123K	123	Missense	distal	3	no	8.540	7.724	EPSD	COSMIC	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q13043	STK4	O14757	CHEK1	T122	R115L	115	Missense	distal	-7	no	6.461	5.836	EPSD	COSMIC;GDSC;CCLE	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q13043	STK4	O14757	CHEK1	T122	E123K	123	Missense	proximal	1	no	6.461	6.387	EPSD	COSMIC	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q13043	STK4	O14757	CHEK1	T187	V184M	184	Missense	distal	-3	no	2.683	5.998	EPSD	COSMIC	5.604	Gain
CAMK_CAMKL_CHK1_CHEK1_ST	Q13043	STK4	O14757	CHEK1	S307	R310W	310	Missense	distal	3	no	12.367	12.229	EPSD	COSMIC	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q13043	STK4	O14757	CHEK1	S307	V312M	312	Missense	distal	5	no	12.367	12.340	EPSD	COSMIC	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q13043	STK4	O14757	CHEK1	S307	R304H	304	Missense	distal	-3	no	12.367	6.558	EPSD	COSMIC	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q13043	STK4	O14757	CHEK1	T387	R384S	384	Missense	distal	-3	no	8.578	-1.117	EPSD	COSMIC	5.604	Loss
CAMK_CAMKL_CHK1_CHEK1_ST	O75592	MYCBP2	O14757	CHEK1	S87	E93D	93	Missense	distal	6	no	9.871	9.958	EPSD	COSMIC	5.604	Up-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	O75592	MYCBP2	O14757	CHEK1	S89	V96L	96	Missense	distal	7	no	9.675	9.538	EPSD	COSMIC	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	O75592	MYCBP2	O14757	CHEK1	S89	E93D	93	Missense	distal	4	no	9.675	9.767	EPSD	COSMIC	5.604	Up-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	O75592	MYCBP2	O14757	CHEK1	S89	V96A	96	Missense	distal	7	no	9.675	9.595	EPSD	COSMIC	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	O75592	MYCBP2	O14757	CHEK1	S89	T95A	95	Missense	distal	6	no	9.675	9.752	EPSD	COSMIC	5.604	Up-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	O75592	MYCBP2	O14757	CHEK1	S351	I349V	349	Missense	proximal	-2	no	9.354	9.417	EPSD	COSMIC	5.604	Up-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	O75592	MYCBP2	O14757	CHEK1	S376	E373K	373	Missense	distal	-3	no	2.896	6.159	EPSD	COSMIC	5.604	Gain
CAMK_CAMKL_CHK1_CHEK1_ST	O75592	MYCBP2	O14757	CHEK1	S861	P863A	863	Missense	proximal	2	no	12.192	12.725	EPSD	COSMIC	5.604	Up-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	O75592	MYCBP2	O14757	CHEK1	S861	A857T	857	Missense	distal	-4	no	12.192	11.762	EPSD	COSMIC	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	O75592	MYCBP2	O14757	CHEK1	S1123	D1118N	1118	Missense	distal	-5	no	13.742	15.010	EPSD	COSMIC	5.604	Up-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	O75592	MYCBP2	O14757	CHEK1	T1148	A1154T	1154	Missense	distal	6	no	9.680	9.602	EPSD	COSMIC	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	O75592	MYCBP2	O14757	CHEK1	T1148	R1145S	1145	Missense	distal	-3	no	9.680	-0.016	EPSD	COSMIC	5.604	Loss
CAMK_CAMKL_CHK1_CHEK1_ST	O75592	MYCBP2	O14757	CHEK1	S1176	G1173C	1173	Missense	distal	-3	no	6.584	6.267	EPSD	COSMIC	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	O75592	MYCBP2	O14757	CHEK1	S1176	A1183S	1183	Missense	distal	7	no	6.584	6.534	EPSD	COSMIC	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	O75592	MYCBP2	O14757	CHEK1	S1176	E1178Q	1178	Missense	proximal	2	no	6.584	6.468	EPSD	COSMIC	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	O75592	MYCBP2	O14757	CHEK1	S1189	K1186N	1186	Missense	distal	-3	no	7.319	0.776	EPSD	COSMIC	5.604	Loss
CAMK_CAMKL_CHK1_CHEK1_ST	O75592	MYCBP2	O14757	CHEK1	S1189	A1183S	1183	Missense	distal	-6	no	7.319	7.445	EPSD	COSMIC	5.604	Up-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	O75592	MYCBP2	O14757	CHEK1	S1189	K1190R	1190	Missense	proximal	1	no	7.319	7.318	EPSD	COSMIC	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	O75592	MYCBP2	O14757	CHEK1	S1189	S1189C	1189	Missense	central	0	yes	7.319	0.000	EPSD	COSMIC	5.604	Loss
CAMK_CAMKL_CHK1_CHEK1_ST	O75592	MYCBP2	O14757	CHEK1	S1472	G1474A	1474	Missense	proximal	2	no	7.680	8.201	EPSD	COSMIC;GDSC;CCLE	5.604	Up-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	O75592	MYCBP2	O14757	CHEK1	S1472	H1477L	1477	Missense	distal	5	no	7.680	7.524	EPSD	COSMIC	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	O75592	MYCBP2	O14757	CHEK1	S1472	L1466M	1466	Missense	distal	-6	no	7.680	7.718	EPSD	COSMIC	5.604	Up-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	O75592	MYCBP2	O14757	CHEK1	S1586	S1586R	1586	Missense	central	0	yes	6.682	0.000	EPSD	COSMIC	5.604	Loss
CAMK_CAMKL_CHK1_CHEK1_ST	O75592	MYCBP2	O14757	CHEK1	S1757	T1764M	1764	Missense	distal	7	no	7.310	7.362	EPSD	COSMIC	5.604	Up-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	O75592	MYCBP2	O14757	CHEK1	S1757	T1764R	1764	Missense	distal	7	no	7.310	7.470	EPSD	COSMIC	5.604	Up-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	O75592	MYCBP2	O14757	CHEK1	S1757	L1760F	1760	Missense	distal	3	no	7.310	7.933	EPSD	COSMIC	5.604	Up-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	O75592	MYCBP2	O14757	CHEK1	T1767	T1764R	1764	Missense	distal	-3	no	-13.556	7.013	EPSD	COSMIC	5.604	Gain
CAMK_CAMKL_CHK1_CHEK1_ST	O75592	MYCBP2	O14757	CHEK1	S2353	R2358G	2358	Missense	distal	5	no	6.610	6.522	EPSD	COSMIC	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	O75592	MYCBP2	O14757	CHEK1	S2353	L2349P	2349	Missense	distal	-4	no	6.610	6.794	EPSD	COSMIC	5.604	Up-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	O75592	MYCBP2	O14757	CHEK1	S2353	P2359S	2359	Missense	distal	6	no	6.610	5.991	EPSD	COSMIC	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	O75592	MYCBP2	O14757	CHEK1	S2353	P2356S	2356	Missense	distal	3	no	6.610	6.281	EPSD	COSMIC	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	O75592	MYCBP2	O14757	CHEK1	T2355	R2358G	2358	Missense	distal	3	no	6.273	6.188	EPSD	COSMIC	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	O75592	MYCBP2	O14757	CHEK1	T2355	L2349P	2349	Missense	distal	-6	no	6.273	6.346	EPSD	COSMIC	5.604	Up-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	O75592	MYCBP2	O14757	CHEK1	T2355	P2359S	2359	Missense	distal	4	no	6.273	6.133	EPSD	COSMIC	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	O75592	MYCBP2	O14757	CHEK1	T2355	P2356S	2356	Missense	proximal	1	no	6.273	6.310	EPSD	COSMIC	5.604	Up-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	O75592	MYCBP2	O14757	CHEK1	S2661	N2657K	2657	Missense	distal	-4	no	7.309	7.424	EPSD	COSMIC	5.604	Up-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	O75592	MYCBP2	O14757	CHEK1	S2745	A2739S	2739	Missense	distal	-6	no	9.153	9.279	EPSD	COSMIC	5.604	Up-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	O75592	MYCBP2	O14757	CHEK1	S2768	S2762Y	2762	Missense	distal	-6	no	10.948	11.110	EPSD	COSMIC	5.604	Up-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	O75592	MYCBP2	O14757	CHEK1	S2774	R2780Q	2780	Missense	distal	6	no	6.470	6.464	EPSD	COSMIC	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	O75592	MYCBP2	O14757	CHEK1	S2783	R2780Q	2780	Missense	distal	-3	no	9.509	2.302	EPSD	COSMIC	5.604	Loss
CAMK_CAMKL_CHK1_CHEK1_ST	O75592	MYCBP2	O14757	CHEK1	S2783	S2783F	2783	Missense	central	0	yes	9.509	0.000	EPSD	COSMIC	5.604	Loss
CAMK_CAMKL_CHK1_CHEK1_ST	O75592	MYCBP2	O14757	CHEK1	S2783	S2782L	2782	Missense	proximal	-1	no	9.509	9.769	EPSD	COSMIC	5.604	Up-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	O75592	MYCBP2	O14757	CHEK1	S2794	S2797L	2797	Missense	distal	3	no	6.415	5.981	EPSD	COSMIC	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	O75592	MYCBP2	O14757	CHEK1	S2794	S2800N	2800	Missense	distal	6	no	6.415	6.549	EPSD	COSMIC	5.604	Up-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	O75592	MYCBP2	O14757	CHEK1	S2806	S2800N	2800	Missense	distal	-6	no	10.069	10.110	EPSD	COSMIC	5.604	Up-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	O75592	MYCBP2	O14757	CHEK1	S2831	R2830H	2830	Missense	proximal	-1	no	7.183	7.308	EPSD	COSMIC	5.604	Up-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	O75592	MYCBP2	O14757	CHEK1	S2831	R2828W	2828	Missense	distal	-3	no	7.183	-26.421	EPSD	COSMIC	5.604	Loss
CAMK_CAMKL_CHK1_CHEK1_ST	O75592	MYCBP2	O14757	CHEK1	S2831	P2827L	2827	Missense	distal	-4	no	7.183	6.999	EPSD	COSMIC	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	O75592	MYCBP2	O14757	CHEK1	S2833	P2840S	2840	Missense	distal	7	no	5.981	5.925	EPSD	COSMIC	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	O75592	MYCBP2	O14757	CHEK1	S2833	R2830H	2830	Missense	distal	-3	no	5.981	0.171	EPSD	COSMIC	5.604	Loss
CAMK_CAMKL_CHK1_CHEK1_ST	O75592	MYCBP2	O14757	CHEK1	S2833	R2828W	2828	Missense	distal	-5	no	5.981	5.122	EPSD	COSMIC	5.604	Loss
CAMK_CAMKL_CHK1_CHEK1_ST	O75592	MYCBP2	O14757	CHEK1	S2833	P2827L	2827	Missense	distal	-6	no	5.981	5.907	EPSD	COSMIC	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	O75592	MYCBP2	O14757	CHEK1	S2882	V2886L	2886	Missense	distal	4	no	6.114	6.039	EPSD	COSMIC	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	O75592	MYCBP2	O14757	CHEK1	S2882	R2879T	2879	Missense	distal	-3	no	6.114	-14.455	EPSD	COSMIC	5.604	Loss
CAMK_CAMKL_CHK1_CHEK1_ST	O75592	MYCBP2	O14757	CHEK1	S2907	D2914N	2914	Missense	distal	7	no	7.040	6.879	EPSD	COSMIC	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	O75592	MYCBP2	O14757	CHEK1	S2907	D2914G	2914	Missense	distal	7	no	7.040	6.748	EPSD	COSMIC	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	O75592	MYCBP2	O14757	CHEK1	S2907	T2909A	2909	Missense	proximal	2	no	7.040	7.888	EPSD	COSMIC	5.604	Up-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	O75592	MYCBP2	O14757	CHEK1	S2907	T2909I	2909	Missense	proximal	2	no	7.040	6.926	EPSD	COSMIC	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	O75592	MYCBP2	O14757	CHEK1	S2907	S2911N	2911	Missense	distal	4	no	7.040	7.060	EPSD	COSMIC	5.604	Up-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	O75592	MYCBP2	O14757	CHEK1	S3388	P3392S	3392	Missense	distal	4	no	6.107	5.967	EPSD	COSMIC	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	O75592	MYCBP2	O14757	CHEK1	S3388	P3390F	3390	Missense	proximal	2	no	6.107	6.039	EPSD	COSMIC	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	O75592	MYCBP2	O14757	CHEK1	S3440	E3445K	3445	Missense	distal	5	no	12.195	12.129	EPSD	COSMIC	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	O75592	MYCBP2	O14757	CHEK1	S3467	I3460V	3460	Missense	distal	-7	no	9.344	9.781	EPSD	COSMIC	5.604	Up-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	O75592	MYCBP2	O14757	CHEK1	S3489	A3490T	3490	Missense	proximal	1	no	10.182	10.171	EPSD	COSMIC	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	O75592	MYCBP2	O14757	CHEK1	S3489	A3490V	3490	Missense	proximal	1	no	10.182	10.157	EPSD	COSMIC	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	O75592	MYCBP2	O14757	CHEK1	S3758	R3755C	3755	Missense	distal	-3	no	10.523	2.431	EPSD	COSMIC	5.604	Loss
CAMK_CAMKL_CHK1_CHEK1_ST	O75592	MYCBP2	O14757	CHEK1	S4022	Q4019R	4019	Missense	distal	-3	no	2.211	9.418	EPSD	COSMIC	5.604	Gain
CAMK_CAMKL_CHK1_CHEK1_ST	O75592	MYCBP2	O14757	CHEK1	T4089	G4092V	4092	Missense	distal	3	no	7.236	7.662	EPSD	COSMIC	5.604	Up-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	O75592	MYCBP2	O14757	CHEK1	S4591	T4590A	4590	Missense	proximal	-1	no	9.205	9.334	EPSD	COSMIC	5.604	Up-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	O75592	MYCBP2	O14757	CHEK1	S4591	T4590N	4590	Missense	proximal	-1	no	9.205	9.219	EPSD	COSMIC	5.604	Up-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	O75592	MYCBP2	O14757	CHEK1	S4591	S4591N	4591	Missense	central	0	yes	9.205	0.000	EPSD	COSMIC	5.604	Loss
CAMK_CAMKL_CHK1_CHEK1_ST	Q9BRD0	BUD13	O14757	CHEK1	S18	E11Q	11	Missense	distal	-7	no	17.342	17.117	PhosphoSitePlus	COSMIC	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q9BRD0	BUD13	O14757	CHEK1	T135	R132H	132	Missense	distal	-3	no	9.017	3.207	EPSD	COSMIC	5.604	Loss
CAMK_CAMKL_CHK1_CHEK1_ST	Q9BRD0	BUD13	O14757	CHEK1	T135	P128S	128	Missense	distal	-7	no	9.017	9.687	EPSD	COSMIC	5.604	Up-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q9BRD0	BUD13	O14757	CHEK1	T135	R130S	130	Missense	distal	-5	no	9.017	8.805	EPSD	COSMIC	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q9BRD0	BUD13	O14757	CHEK1	T147	R144H	144	Missense	distal	-3	no	10.525	4.716	EPSD	COSMIC	5.604	Loss
CAMK_CAMKL_CHK1_CHEK1_ST	Q9BRD0	BUD13	O14757	CHEK1	T147	H145Q	145	Missense	proximal	-2	no	10.525	10.507	EPSD	COSMIC	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q9BRD0	BUD13	O14757	CHEK1	T159	H157R	157	Missense	proximal	-2	no	8.933	8.869	EPSD	COSMIC	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q9BRD0	BUD13	O14757	CHEK1	T159	R156C	156	Missense	distal	-3	no	8.933	0.842	EPSD	COSMIC	5.604	Loss
CAMK_CAMKL_CHK1_CHEK1_ST	Q9BRD0	BUD13	O14757	CHEK1	T159	R156H	156	Missense	distal	-3	no	8.933	3.124	EPSD	COSMIC	5.604	Loss
CAMK_CAMKL_CHK1_CHEK1_ST	Q9BRD0	BUD13	O14757	CHEK1	T159	P162S	162	Missense	distal	3	no	8.933	8.604	EPSD	COSMIC	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q9BRD0	BUD13	O14757	CHEK1	S172	P177L	177	Missense	distal	5	no	7.652	7.490	EPSD	COSMIC	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q9BRD0	BUD13	O14757	CHEK1	S184	D183N	183	Missense	proximal	-1	no	11.487	11.576	EPSD	COSMIC	5.604	Up-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q9BRD0	BUD13	O14757	CHEK1	S184	P177L	177	Missense	distal	-7	no	11.487	11.273	EPSD	COSMIC	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q9BRD0	BUD13	O14757	CHEK1	S197	R194H	194	Missense	distal	-3	no	11.188	5.378	EPSD	COSMIC	5.604	Loss
CAMK_CAMKL_CHK1_CHEK1_ST	Q9BRD0	BUD13	O14757	CHEK1	S197	S197P	197	Missense	central	0	yes	11.188	0.000	EPSD	COSMIC	5.604	Loss
CAMK_CAMKL_CHK1_CHEK1_ST	Q9BRD0	BUD13	O14757	CHEK1	S197	P200L	200	Missense	distal	3	no	11.188	10.424	EPSD	COSMIC	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q9BRD0	BUD13	O14757	CHEK1	S210	Q207K	207	Missense	distal	-3	no	2.908	6.290	EPSD	COSMIC	5.604	Gain
CAMK_CAMKL_CHK1_CHEK1_ST	Q9BRD0	BUD13	O14757	CHEK1	S235	R242K	242	Missense	distal	7	no	9.590	9.665	EPSD	COSMIC	5.604	Up-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q9BRD0	BUD13	O14757	CHEK1	S235	D237H	237	Missense	proximal	2	no	9.590	9.047	EPSD	COSMIC	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q9BRD0	BUD13	O14757	CHEK1	S235	R232H	232	Missense	distal	-3	no	9.590	3.781	EPSD	COSMIC	5.604	Loss
CAMK_CAMKL_CHK1_CHEK1_ST	Q9BRD0	BUD13	O14757	CHEK1	S235	D237A	237	Missense	proximal	2	no	9.590	9.580	EPSD	COSMIC	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q9BRD0	BUD13	O14757	CHEK1	S235	G234S	234	Missense	proximal	-1	no	9.590	9.412	EPSD	COSMIC	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q9BRD0	BUD13	O14757	CHEK1	S271	R268C	268	Missense	distal	-3	no	7.796	-0.295	EPSD	COSMIC	5.604	Loss
CAMK_CAMKL_CHK1_CHEK1_ST	Q9BRD0	BUD13	O14757	CHEK1	S271	H269Y	269	Missense	proximal	-2	no	7.796	7.745	EPSD	COSMIC	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q9BRD0	BUD13	O14757	CHEK1	S296	P291Q	291	Missense	distal	-5	no	9.392	10.726	EPSD	COSMIC	5.604	Up-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q9BRD0	BUD13	O14757	CHEK1	S385	H383Y	383	Missense	proximal	-2	no	8.920	8.869	EPSD	COSMIC	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q9BRD0	BUD13	O14757	CHEK1	S385	S388C	388	Missense	distal	3	no	8.920	7.971	EPSD	COSMIC	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q9BRD0	BUD13	O14757	CHEK1	S401	S407P	407	Missense	distal	6	no	11.927	12.547	EPSD	COSMIC	5.604	Up-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	O60343	TBC1D4	O14757	CHEK1	S66	Q67R	67	Missense	proximal	1	no	9.780	9.772	EPSD	COSMIC	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	O60343	TBC1D4	O14757	CHEK1	S66	G73D	73	Missense	distal	7	no	9.780	10.073	EPSD	COSMIC	5.604	Up-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	O60343	TBC1D4	O14757	CHEK1	S66	E70K	70	Missense	distal	4	no	9.780	9.774	EPSD	COSMIC	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	O60343	TBC1D4	O14757	CHEK1	S66	G73S	73	Missense	distal	7	no	9.780	9.682	EPSD	COSMIC	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	O60343	TBC1D4	O14757	CHEK1	S318	G321S	321	Missense	distal	3	no	9.143	9.230	EPSD	COSMIC;GDSC	5.604	Up-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	O60343	TBC1D4	O14757	CHEK1	S318	R324W	324	Missense	distal	6	no	9.143	9.610	EPSD	COSMIC	5.604	Up-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	O60343	TBC1D4	O14757	CHEK1	S341	P335L	335	Missense	distal	-6	no	7.708	7.635	EPSD	COSMIC	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	O60343	TBC1D4	O14757	CHEK1	S341	S344C	344	Missense	distal	3	no	7.708	6.758	EPSD	COSMIC	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	O60343	TBC1D4	O14757	CHEK1	T356	S351L	351	Missense	distal	-5	no	3.595	6.783	EPSD	COSMIC	5.604	Gain
CAMK_CAMKL_CHK1_CHEK1_ST	O60343	TBC1D4	O14757	CHEK1	S485	Q481H	481	Missense	distal	-4	no	10.062	9.704	EPSD;PhosphoSitePlus	COSMIC	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	O60343	TBC1D4	O14757	CHEK1	S751	L758I	758	Missense	distal	7	no	10.184	9.900	EPSD	COSMIC	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	O60343	TBC1D4	O14757	CHEK1	S771	R773Q	773	Missense	proximal	2	no	9.775	10.304	EPSD	COSMIC	5.604	Up-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	O60343	TBC1D4	O14757	CHEK1	S771	R775H	775	Missense	distal	4	no	9.775	9.936	EPSD	COSMIC	5.604	Up-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	O60343	TBC1D4	O14757	CHEK1	S782	S787A	787	Missense	distal	5	no	8.379	8.398	EPSD	COSMIC	5.604	Up-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	O60343	TBC1D4	O14757	CHEK1	S782	A781D	781	Missense	proximal	-1	no	8.379	8.175	EPSD	COSMIC	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	O60343	TBC1D4	O14757	CHEK1	S782	P783A	783	Missense	proximal	1	no	8.379	8.434	EPSD	COSMIC	5.604	Up-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	O60343	TBC1D4	O14757	CHEK1	S782	R775H	775	Missense	distal	-7	no	8.379	8.320	EPSD	COSMIC	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	O60343	TBC1D4	O14757	CHEK1	S822	G823V	823	Missense	proximal	1	no	9.075	9.051	EPSD	COSMIC	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	O60343	TBC1D4	O14757	CHEK1	S822	G823W	823	Missense	proximal	1	no	9.075	9.053	EPSD	COSMIC	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	O60343	TBC1D4	O14757	CHEK1	S822	V819I	819	Missense	distal	-3	no	9.075	8.780	EPSD	COSMIC	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	O60343	TBC1D4	O14757	CHEK1	S951	S951F	951	Missense	central	0	yes	6.741	0.000	EPSD	COSMIC	5.604	Loss
CAMK_CAMKL_CHK1_CHEK1_ST	O60343	TBC1D4	O14757	CHEK1	S1126	L1123R	1123	Missense	distal	-3	no	-3.754	14.793	EPSD	COSMIC;GDSC;CCLE	5.604	Gain
CAMK_CAMKL_CHK1_CHEK1_ST	O60343	TBC1D4	O14757	CHEK1	S1154	T1147K	1147	Missense	distal	-7	no	3.876	5.663	EPSD	COSMIC	5.604	Gain
CAMK_CAMKL_CHK1_CHEK1_ST	O60343	TBC1D4	O14757	CHEK1	S1207	A1205T	1205	Missense	proximal	-2	no	11.305	11.444	EPSD	COSMIC	5.604	Up-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	P36507	MAP2K2	O14757	CHEK1	S30	E27K	27	Missense	distal	-3	no	4.946	8.209	EPSD	COSMIC	5.604	Gain
CAMK_CAMKL_CHK1_CHEK1_ST	P36507	MAP2K2	O14757	CHEK1	T59	F57C	57	Missense	proximal	-2	no	7.692	7.450	PhosphoSitePlus	COSMIC	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	P36507	MAP2K2	O14757	CHEK1	T59	V64D	64	Missense	distal	5	no	7.692	7.864	PhosphoSitePlus	COSMIC	5.604	Up-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	P36507	MAP2K2	O14757	CHEK1	T59	K61T	61	Missense	proximal	2	no	7.692	6.709	PhosphoSitePlus	COSMIC	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	P36507	MAP2K2	O14757	CHEK1	T59	Q60H	60	Missense	proximal	1	no	7.692	7.618	PhosphoSitePlus	COSMIC	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	P36507	MAP2K2	O14757	CHEK1	S306	D311Y	311	Missense	distal	5	no	8.439	7.898	EPSD	COSMIC	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	P36507	MAP2K2	O14757	CHEK1	S306	P300R	300	Missense	distal	-6	no	8.439	8.262	EPSD	COSMIC	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	P36507	MAP2K2	O14757	CHEK1	S306	R299M	299	Missense	distal	-7	no	8.439	8.298	EPSD	COSMIC	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	P36507	MAP2K2	O14757	CHEK1	S306	R299S	299	Missense	distal	-7	no	8.439	8.699	EPSD	COSMIC	5.604	Up-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	P36507	MAP2K2	O14757	CHEK1	S306	R303H	303	Missense	distal	-3	no	8.439	2.630	EPSD	COSMIC	5.604	Loss
CAMK_CAMKL_CHK1_CHEK1_ST	P36507	MAP2K2	O14757	CHEK1	S306	G309R	309	Missense	distal	3	no	8.439	8.524	EPSD	COSMIC	5.604	Up-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	P36507	MAP2K2	O14757	CHEK1	S306	R313Q	313	Missense	distal	7	no	8.439	8.594	EPSD	COSMIC	5.604	Up-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	P36507	MAP2K2	O14757	CHEK1	S312	G309R	309	Missense	distal	-3	no	0.210	7.984	EPSD	COSMIC	5.604	Gain
CAMK_CAMKL_CHK1_CHEK1_ST	Q9GZR7	DDX24	O14757	CHEK1	S82	E89K	89	Missense	distal	7	no	7.723	7.557	PhosphoSitePlus	COSMIC	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q9GZR7	DDX24	O14757	CHEK1	S82	K75N	75	Missense	distal	-7	no	7.723	6.265	PhosphoSitePlus	COSMIC	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q9GZR7	DDX24	O14757	CHEK1	S82	E88Q	88	Missense	distal	6	no	7.723	8.074	PhosphoSitePlus	COSMIC	5.604	Up-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q9GZR7	DDX24	O14757	CHEK1	S82	E85K	85	Missense	distal	3	no	7.723	6.907	PhosphoSitePlus	COSMIC	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q9GZR7	DDX24	O14757	CHEK1	S208	S213G	213	Missense	distal	5	no	8.739	8.548	EPSD	COSMIC	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q9GZR7	DDX24	O14757	CHEK1	S208	R201G	201	Missense	distal	-7	no	8.739	8.777	EPSD	COSMIC	5.604	Up-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q9GZR7	DDX24	O14757	CHEK1	S208	P215S	215	Missense	distal	7	no	8.739	8.683	EPSD	COSMIC	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q9GZR7	DDX24	O14757	CHEK1	S208	R201M	201	Missense	distal	-7	no	8.739	8.598	EPSD	COSMIC	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q9GZR7	DDX24	O14757	CHEK1	S208	R205Q	205	Missense	distal	-3	no	8.739	1.532	EPSD	COSMIC	5.604	Loss
CAMK_CAMKL_CHK1_CHEK1_ST	Q9GZR7	DDX24	O14757	CHEK1	S287	E284K	284	Missense	distal	-3	no	5.332	8.595	EPSD	COSMIC	5.604	Gain
CAMK_CAMKL_CHK1_CHEK1_ST	Q9GZR7	DDX24	O14757	CHEK1	T532	M529I	529	Missense	distal	-3	no	5.746	2.137	EPSD	COSMIC	5.604	Loss
CAMK_CAMKL_CHK1_CHEK1_ST	Q9GZR7	DDX24	O14757	CHEK1	T532	L535R	535	Missense	distal	3	no	5.746	6.178	EPSD	COSMIC	5.604	Up-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q9GZR7	DDX24	O14757	CHEK1	T532	K527N	527	Missense	distal	-5	no	5.746	4.852	EPSD	COSMIC	5.604	Loss
CAMK_CAMKL_CHK1_CHEK1_ST	Q9GZR7	DDX24	O14757	CHEK1	S797	R793C	793	Missense	distal	-4	no	7.379	7.005	EPSD	COSMIC	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q9GZR7	DDX24	O14757	CHEK1	S797	P799S	799	Missense	proximal	2	no	7.379	7.456	EPSD	COSMIC	5.604	Up-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q9GZR7	DDX24	O14757	CHEK1	S797	R793H	793	Missense	distal	-4	no	7.379	7.182	EPSD	COSMIC	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q14247	CTTN	O14757	CHEK1	S150	G143W	143	Missense	distal	-7	no	10.762	9.178	EPSD	COSMIC	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q14247	CTTN	O14757	CHEK1	S150	Y154C	154	Missense	distal	4	no	10.762	10.742	EPSD	COSMIC;CCLE	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q14247	CTTN	O14757	CHEK1	S155	Y154C	154	Missense	proximal	-1	no	6.590	6.457	EPSD	COSMIC;CCLE	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q14247	CTTN	O14757	CHEK1	S187	D190N	190	Missense	distal	3	no	9.171	8.455	EPSD	COSMIC	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q14247	CTTN	O14757	CHEK1	S192	D190N	190	Missense	proximal	-2	no	9.783	9.925	EPSD	COSMIC	5.604	Up-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q14247	CTTN	O14757	CHEK1	S224	S224F	224	Missense	central	0	yes	8.271	0.000	EPSD	COSMIC	5.604	Loss
CAMK_CAMKL_CHK1_CHEK1_ST	Q14247	CTTN	O14757	CHEK1	S282	R279W	279	Missense	distal	-3	no	8.959	-24.644	EPSD	COSMIC	5.604	Loss
CAMK_CAMKL_CHK1_CHEK1_ST	Q14247	CTTN	O14757	CHEK1	S282	F287L	287	Missense	distal	5	no	8.959	9.040	EPSD	COSMIC	5.604	Up-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q14247	CTTN	O14757	CHEK1	S282	S277L	277	Missense	distal	-5	no	8.959	12.147	EPSD	COSMIC	5.604	Up-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q14247	CTTN	O14757	CHEK1	S322	R316W	316	Missense	distal	-6	no	5.399	5.719	EPSD	COSMIC	5.604	Gain
CAMK_CAMKL_CHK1_CHEK1_ST	Q14247	CTTN	O14757	CHEK1	T399	Q394K	394	Missense	distal	-5	no	6.087	7.659	EPSD	COSMIC	5.604	Up-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q14247	CTTN	O14757	CHEK1	T399	R396T	396	Missense	distal	-3	no	6.087	-14.482	EPSD	COSMIC	5.604	Loss
CAMK_CAMKL_CHK1_CHEK1_ST	Q14247	CTTN	O14757	CHEK1	S405	T411I	411	Missense	distal	6	no	5.971	5.703	EPSD	COSMIC	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q14247	CTTN	O14757	CHEK1	S417	T411I	411	Missense	distal	-6	no	7.084	7.014	EPSD	COSMIC	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q14247	CTTN	O14757	CHEK1	S417	V420I	420	Missense	distal	3	no	7.084	6.371	EPSD	COSMIC	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q9BTD8	RBM42	O14757	CHEK1	S406	V412M	412	Missense	distal	6	no	11.286	11.410	PhosphoSitePlus	COSMIC	5.604	Up-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q9BTD8	RBM42	O14757	CHEK1	S406	R399C	399	Missense	distal	-7	no	11.286	10.558	PhosphoSitePlus	COSMIC	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q9BTD8	RBM42	O14757	CHEK1	S406	P405L	405	Missense	proximal	-1	no	11.286	11.099	PhosphoSitePlus	COSMIC	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q9BTD8	RBM42	O14757	CHEK1	S406	V412L	412	Missense	distal	6	no	11.286	11.419	PhosphoSitePlus	COSMIC	5.604	Up-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q9BTD8	RBM42	O14757	CHEK1	S406	F407C	407	Missense	proximal	1	no	11.286	11.306	PhosphoSitePlus	COSMIC	5.604	Up-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q9BTD8	RBM42	O14757	CHEK1	S406	S406C	406	Missense	central	0	yes	11.286	0.000	PhosphoSitePlus	COSMIC	5.604	Loss
CAMK_CAMKL_CHK1_CHEK1_ST	Q9BTD8	RBM42	O14757	CHEK1	S406	F407L	407	Missense	proximal	1	no	11.286	11.281	PhosphoSitePlus	COSMIC	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q9BTD8	RBM42	O14757	CHEK1	S406	R403H	403	Missense	distal	-3	no	11.286	5.476	PhosphoSitePlus	COSMIC	5.604	Loss
CAMK_CAMKL_CHK1_CHEK1_ST	P39748	FEN1	O14757	CHEK1	S335	R332H	332	Missense	distal	-3	no	8.627	2.818	EPSD	COSMIC	5.604	Loss
CAMK_CAMKL_CHK1_CHEK1_ST	P39748	FEN1	O14757	CHEK1	S335	R332S	332	Missense	distal	-3	no	8.627	-1.069	EPSD	COSMIC	5.604	Loss
CAMK_CAMKL_CHK1_CHEK1_ST	Q99848	EBNA1BP2	O14757	CHEK1	T134	P129S	129	Missense	distal	-5	no	4.931	6.450	EPSD	COSMIC	5.604	Gain
CAMK_CAMKL_CHK1_CHEK1_ST	Q99848	EBNA1BP2	O14757	CHEK1	S207	L213F	213	Missense	distal	6	no	6.142	6.136	EPSD	COSMIC	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q13263	TRIM28	O14757	CHEK1	T34	T34P	34	Missense	central	0	yes	5.619	0.000	EPSD	COSMIC	5.604	Loss
CAMK_CAMKL_CHK1_CHEK1_ST	Q13263	TRIM28	O14757	CHEK1	T34	A38T	38	Missense	distal	4	no	5.619	5.437	EPSD	COSMIC	5.604	Loss
CAMK_CAMKL_CHK1_CHEK1_ST	Q13263	TRIM28	O14757	CHEK1	S138	T144N	144	Missense	distal	6	no	5.776	5.600	EPSD	COSMIC	5.604	Loss
CAMK_CAMKL_CHK1_CHEK1_ST	Q13263	TRIM28	O14757	CHEK1	S138	A142T	142	Missense	distal	4	no	5.776	5.594	EPSD	COSMIC	5.604	Loss
CAMK_CAMKL_CHK1_CHEK1_ST	Q13263	TRIM28	O14757	CHEK1	S138	G139D	139	Missense	proximal	1	no	5.776	5.864	EPSD	COSMIC	5.604	Up-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q13263	TRIM28	O14757	CHEK1	S138	A143T	143	Missense	distal	5	no	5.776	5.535	EPSD	COSMIC	5.604	Loss
CAMK_CAMKL_CHK1_CHEK1_ST	Q13263	TRIM28	O14757	CHEK1	S285	R282H	282	Missense	distal	-3	no	8.908	3.099	EPSD	COSMIC	5.604	Loss
CAMK_CAMKL_CHK1_CHEK1_ST	Q13263	TRIM28	O14757	CHEK1	S285	D286E	286	Missense	proximal	1	no	8.908	8.904	EPSD	COSMIC	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q13263	TRIM28	O14757	CHEK1	S285	K289Q	289	Missense	distal	4	no	8.908	9.006	EPSD	COSMIC	5.604	Up-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q13263	TRIM28	O14757	CHEK1	S437	S437F	437	Missense	central	0	yes	9.298	0.000	EPSD	COSMIC	5.604	Loss
CAMK_CAMKL_CHK1_CHEK1_ST	Q13263	TRIM28	O14757	CHEK1	S437	P442L	442	Missense	distal	5	no	9.298	9.136	EPSD	COSMIC;GDSC	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q13263	TRIM28	O14757	CHEK1	S473	E477D	477	Missense	distal	4	no	8.214	8.306	PhosphoSitePlus	COSMIC	5.604	Up-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q13263	TRIM28	O14757	CHEK1	S473	G467D	467	Missense	distal	-6	no	8.214	8.004	PhosphoSitePlus	COSMIC	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q13263	TRIM28	O14757	CHEK1	S473	R472S	472	Missense	proximal	-1	no	8.214	8.053	PhosphoSitePlus	COSMIC	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q13263	TRIM28	O14757	CHEK1	S473	G476C	476	Missense	distal	3	no	8.214	7.352	PhosphoSitePlus	COSMIC	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q13263	TRIM28	O14757	CHEK1	S473	G480V	480	Missense	distal	7	no	8.214	8.244	PhosphoSitePlus	COSMIC	5.604	Up-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q13263	TRIM28	O14757	CHEK1	S594	R591L	591	Missense	distal	-3	no	8.218	-10.329	EPSD	COSMIC	5.604	Loss
CAMK_CAMKL_CHK1_CHEK1_ST	Q13263	TRIM28	O14757	CHEK1	S594	P590L	590	Missense	distal	-4	no	8.218	8.033	EPSD	COSMIC	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q13263	TRIM28	O14757	CHEK1	S594	R591C	591	Missense	distal	-3	no	8.218	0.126	EPSD	COSMIC	5.604	Loss
CAMK_CAMKL_CHK1_CHEK1_ST	Q13263	TRIM28	O14757	CHEK1	S752	P753H	753	Missense	proximal	1	no	6.033	6.030	EPSD	COSMIC	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q13263	TRIM28	O14757	CHEK1	S752	A745G	745	Missense	distal	-7	no	6.033	5.362	EPSD	COSMIC	5.604	Loss
CAMK_CAMKL_CHK1_CHEK1_ST	Q13263	TRIM28	O14757	CHEK1	S752	R746H	746	Missense	distal	-6	no	6.033	6.142	EPSD	COSMIC;GDSC;CCLE	5.604	Up-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q13263	TRIM28	O14757	CHEK1	S756	P753H	753	Missense	distal	-3	no	8.323	9.650	EPSD	COSMIC	5.604	Up-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	P49792	RANBP2	O14757	CHEK1	S313	V307I	307	Missense	distal	-6	no	7.683	7.670	EPSD	COSMIC	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	P49792	RANBP2	O14757	CHEK1	S313	L312F	312	Missense	proximal	-1	no	7.683	7.696	EPSD	COSMIC	5.604	Up-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	P49792	RANBP2	O14757	CHEK1	T1310	A1307V	1307	Missense	distal	-3	no	6.861	5.109	EPSD	COSMIC	5.604	Loss
CAMK_CAMKL_CHK1_CHEK1_ST	P49792	RANBP2	O14757	CHEK1	T1310	V1312A	1312	Missense	proximal	2	no	6.861	7.423	EPSD	COSMIC	5.604	Up-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	P49792	RANBP2	O14757	CHEK1	T1310	A1315G	1315	Missense	distal	5	no	6.861	6.651	EPSD	COSMIC	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	P49792	RANBP2	O14757	CHEK1	T1310	A1315T	1315	Missense	distal	5	no	6.861	6.620	EPSD	COSMIC	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	P49792	RANBP2	O14757	CHEK1	S1833	S1835R	1835	Missense	proximal	2	no	6.053	5.958	EPSD	COSMIC	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	P49792	RANBP2	O14757	CHEK1	S1955	S1953L	1953	Missense	proximal	-2	no	9.165	9.269	EPSD	COSMIC	5.604	Up-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	P49792	RANBP2	O14757	CHEK1	S1972	K1969N	1969	Missense	distal	-3	no	6.041	-0.502	EPSD	COSMIC	5.604	Loss
CAMK_CAMKL_CHK1_CHEK1_ST	P49792	RANBP2	O14757	CHEK1	S1972	D1965G	1965	Missense	distal	-7	no	6.041	6.049	EPSD	COSMIC	5.604	Up-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	P49792	RANBP2	O14757	CHEK1	T1992	T1992P	1992	Missense	central	0	yes	5.696	0.000	EPSD	COSMIC	5.604	Loss
CAMK_CAMKL_CHK1_CHEK1_ST	P49792	RANBP2	O14757	CHEK1	T2458	T2458P	2458	Missense	central	0	yes	6.832	0.000	EPSD	COSMIC	5.604	Loss
CAMK_CAMKL_CHK1_CHEK1_ST	P49792	RANBP2	O14757	CHEK1	S2558	S2555G	2555	Missense	distal	-3	no	3.691	5.613	EPSD	COSMIC	5.604	Gain
CAMK_CAMKL_CHK1_CHEK1_ST	P49792	RANBP2	O14757	CHEK1	S2849	T2846K	2846	Missense	distal	-3	no	-10.534	6.209	EPSD	COSMIC	5.604	Gain
CAMK_CAMKL_CHK1_CHEK1_ST	P49792	RANBP2	O14757	CHEK1	S2889	G2886R	2886	Missense	distal	-3	no	0.600	8.374	EPSD	COSMIC	5.604	Gain
CAMK_CAMKL_CHK1_CHEK1_ST	P49792	RANBP2	O14757	CHEK1	S2900	E2897K	2897	Missense	distal	-3	no	2.521	5.784	EPSD	COSMIC	5.604	Gain
CAMK_CAMKL_CHK1_CHEK1_ST	Q9BQG0	MYBBP1A	O14757	CHEK1	T79	R76H	76	Missense	distal	-3	no	8.017	2.208	EPSD	COSMIC	5.604	Loss
CAMK_CAMKL_CHK1_CHEK1_ST	Q9BQG0	MYBBP1A	O14757	CHEK1	S399	P401L	401	Missense	proximal	2	no	7.515	7.197	EPSD	COSMIC	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q9BQG0	MYBBP1A	O14757	CHEK1	S698	R704H	704	Missense	distal	6	no	7.415	7.703	EPSD	COSMIC	5.604	Up-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q9BQG0	MYBBP1A	O14757	CHEK1	S795	S792R	792	Missense	distal	-3	no	0.124	9.820	EPSD	COSMIC	5.604	Gain
CAMK_CAMKL_CHK1_CHEK1_ST	Q9BQG0	MYBBP1A	O14757	CHEK1	S1000	S1003F	1003	Missense	distal	3	no	6.898	7.087	EPSD	COSMIC	5.604	Up-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q9BQG0	MYBBP1A	O14757	CHEK1	S1243	R1240Q	1240	Missense	distal	-3	no	8.906	1.699	EPSD	COSMIC	5.604	Loss
CAMK_CAMKL_CHK1_CHEK1_ST	Q9BQG0	MYBBP1A	O14757	CHEK1	S1243	R1240W	1240	Missense	distal	-3	no	8.906	-24.697	EPSD	COSMIC	5.604	Loss
CAMK_CAMKL_CHK1_CHEK1_ST	Q9BQG0	MYBBP1A	O14757	CHEK1	S1310	V1305A	1305	Missense	distal	-5	no	10.671	8.232	PhosphoSitePlus	COSMIC	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q9HC62	SENP2	O14757	CHEK1	S32	S34C	34	Missense	proximal	2	no	14.222	13.860	EPSD	COSMIC	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q9HC62	SENP2	O14757	CHEK1	S34	S34C	34	Missense	central	0	yes	10.144	0.000	EPSD	COSMIC	5.604	Loss
CAMK_CAMKL_CHK1_CHEK1_ST	Q9HC62	SENP2	O14757	CHEK1	S333	S335R	335	Missense	proximal	2	no	11.612	11.517	EPSD	COSMIC	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q08AD1	CAMSAP2	O14757	CHEK1	S86	L89F	89	Missense	distal	3	no	9.242	9.864	EPSD	COSMIC	5.604	Up-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q08AD1	CAMSAP2	O14757	CHEK1	S86	C82F	82	Missense	distal	-4	no	9.242	9.066	EPSD	COSMIC	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q08AD1	CAMSAP2	O14757	CHEK1	S415	S416Y	416	Missense	proximal	1	no	9.017	8.999	EPSD	COSMIC	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q08AD1	CAMSAP2	O14757	CHEK1	S415	S414F	414	Missense	proximal	-1	no	9.017	9.291	EPSD	COSMIC	5.604	Up-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q08AD1	CAMSAP2	O14757	CHEK1	S415	Y419F	419	Missense	distal	4	no	9.017	8.941	EPSD	COSMIC	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q08AD1	CAMSAP2	O14757	CHEK1	S416	S416Y	416	Missense	central	0	yes	8.725	0.000	EPSD	COSMIC	5.604	Loss
CAMK_CAMKL_CHK1_CHEK1_ST	Q08AD1	CAMSAP2	O14757	CHEK1	S416	F423L	423	Missense	distal	7	no	8.725	9.148	EPSD	COSMIC	5.604	Up-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q08AD1	CAMSAP2	O14757	CHEK1	S416	S414F	414	Missense	proximal	-2	no	8.725	9.015	EPSD	COSMIC	5.604	Up-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q08AD1	CAMSAP2	O14757	CHEK1	S416	Y419F	419	Missense	distal	3	no	8.725	10.142	EPSD	COSMIC	5.604	Up-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q08AD1	CAMSAP2	O14757	CHEK1	S464	N471K	471	Missense	distal	7	no	9.056	8.995	PhosphoSitePlus	COSMIC	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q08AD1	CAMSAP2	O14757	CHEK1	S484	R480M	480	Missense	distal	-4	no	10.197	10.033	EPSD	COSMIC	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q08AD1	CAMSAP2	O14757	CHEK1	S484	N482K	482	Missense	proximal	-2	no	10.197	9.926	EPSD	COSMIC	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q08AD1	CAMSAP2	O14757	CHEK1	T614	S611R	611	Missense	distal	-3	no	-3.695	6.001	EPSD	COSMIC	5.604	Gain
CAMK_CAMKL_CHK1_CHEK1_ST	Q08AD1	CAMSAP2	O14757	CHEK1	T644	T644I	644	Missense	central	0	yes	9.236	0.000	EPSD	COSMIC	5.604	Loss
CAMK_CAMKL_CHK1_CHEK1_ST	Q08AD1	CAMSAP2	O14757	CHEK1	T644	S639L	639	Missense	distal	-5	no	9.236	12.424	EPSD	COSMIC	5.604	Up-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q08AD1	CAMSAP2	O14757	CHEK1	S677	L672F	672	Missense	distal	-5	no	5.615	2.052	EPSD	COSMIC	5.604	Loss
CAMK_CAMKL_CHK1_CHEK1_ST	Q08AD1	CAMSAP2	O14757	CHEK1	S677	P674L	674	Missense	distal	-3	no	5.615	-5.794	EPSD	COSMIC	5.604	Loss
CAMK_CAMKL_CHK1_CHEK1_ST	Q08AD1	CAMSAP2	O14757	CHEK1	S677	E670D	670	Missense	distal	-7	no	5.615	5.162	EPSD	COSMIC	5.604	Loss
CAMK_CAMKL_CHK1_CHEK1_ST	Q08AD1	CAMSAP2	O14757	CHEK1	S677	L672V	672	Missense	distal	-5	no	5.615	2.139	EPSD	COSMIC	5.604	Loss
CAMK_CAMKL_CHK1_CHEK1_ST	Q08AD1	CAMSAP2	O14757	CHEK1	S687	G686C	686	Missense	proximal	-1	no	7.151	7.169	EPSD	COSMIC	5.604	Up-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q08AD1	CAMSAP2	O14757	CHEK1	S687	S690A	690	Missense	distal	3	no	7.151	7.245	EPSD	COSMIC	5.604	Up-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q08AD1	CAMSAP2	O14757	CHEK1	S687	G686S	686	Missense	proximal	-1	no	7.151	6.973	EPSD	COSMIC	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q08AD1	CAMSAP2	O14757	CHEK1	S699	E702D	702	Missense	distal	3	no	5.540	5.637	EPSD	COSMIC	5.604	Gain
CAMK_CAMKL_CHK1_CHEK1_ST	Q08AD1	CAMSAP2	O14757	CHEK1	T711	L708R	708	Missense	distal	-3	no	-9.444	9.102	EPSD	COSMIC	5.604	Gain
CAMK_CAMKL_CHK1_CHEK1_ST	Q08AD1	CAMSAP2	O14757	CHEK1	T826	A829S	829	Missense	distal	3	no	6.153	6.059	EPSD	COSMIC	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q08AD1	CAMSAP2	O14757	CHEK1	T826	V824I	824	Missense	proximal	-2	no	6.153	6.089	EPSD	COSMIC	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q08AD1	CAMSAP2	O14757	CHEK1	T826	K823N	823	Missense	distal	-3	no	6.153	-0.390	EPSD	COSMIC	5.604	Loss
CAMK_CAMKL_CHK1_CHEK1_ST	Q08AD1	CAMSAP2	O14757	CHEK1	T826	A819S	819	Missense	distal	-7	no	6.153	5.703	EPSD	COSMIC	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q08AD1	CAMSAP2	O14757	CHEK1	T826	D827N	827	Missense	proximal	1	no	6.153	6.045	EPSD	COSMIC	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q08AD1	CAMSAP2	O14757	CHEK1	S844	T837P	837	Missense	distal	-7	no	7.017	7.214	EPSD	COSMIC	5.604	Up-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q08AD1	CAMSAP2	O14757	CHEK1	S844	S842N	842	Missense	proximal	-2	no	7.017	7.206	EPSD	COSMIC	5.604	Up-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q08AD1	CAMSAP2	O14757	CHEK1	S844	D847H	847	Missense	distal	3	no	7.017	5.488	EPSD	COSMIC	5.604	Loss
CAMK_CAMKL_CHK1_CHEK1_ST	Q08AD1	CAMSAP2	O14757	CHEK1	S900	S901Y	901	Missense	proximal	1	no	7.439	7.422	EPSD	COSMIC	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q08AD1	CAMSAP2	O14757	CHEK1	S980	R987Q	987	Missense	distal	7	no	6.922	7.077	EPSD	COSMIC	5.604	Up-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q08AD1	CAMSAP2	O14757	CHEK1	S980	S982F	982	Missense	proximal	2	no	6.922	6.778	EPSD	COSMIC	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q08AD1	CAMSAP2	O14757	CHEK1	T1004	R1001M	1001	Missense	distal	-3	no	9.217	4.068	EPSD	COSMIC	5.604	Loss
CAMK_CAMKL_CHK1_CHEK1_ST	Q08AD1	CAMSAP2	O14757	CHEK1	T1004	D1010G	1010	Missense	distal	6	no	9.217	9.613	EPSD	COSMIC	5.604	Up-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q08AD1	CAMSAP2	O14757	CHEK1	T1004	R1007W	1007	Missense	distal	3	no	9.217	9.079	EPSD	COSMIC	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q08AD1	CAMSAP2	O14757	CHEK1	S1019	R1017M	1017	Missense	proximal	-2	no	8.023	8.065	EPSD	COSMIC	5.604	Up-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q08AD1	CAMSAP2	O14757	CHEK1	S1019	R1014Q	1014	Missense	distal	-5	no	8.023	7.626	EPSD	COSMIC	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q08AD1	CAMSAP2	O14757	CHEK1	S1019	P1013A	1013	Missense	distal	-6	no	8.023	7.799	EPSD	COSMIC	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q08AD1	CAMSAP2	O14757	CHEK1	S1127	I1124M	1124	Missense	distal	-3	no	2.096	5.706	EPSD	COSMIC	5.604	Gain
CAMK_CAMKL_CHK1_CHEK1_ST	Q08AD1	CAMSAP2	O14757	CHEK1	S1268	R1271I	1271	Missense	distal	3	no	9.792	9.420	EPSD	COSMIC	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q08AD1	CAMSAP2	O14757	CHEK1	S1268	K1263Q	1263	Missense	distal	-5	no	9.792	8.220	EPSD	COSMIC	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q08AD1	CAMSAP2	O14757	CHEK1	S1268	K1267N	1267	Missense	proximal	-1	no	9.792	9.997	EPSD	COSMIC	5.604	Up-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q08AD1	CAMSAP2	O14757	CHEK1	S1313	S1313F	1313	Missense	central	0	yes	9.915	0.000	EPSD	COSMIC	5.604	Loss
CAMK_CAMKL_CHK1_CHEK1_ST	Q08AD1	CAMSAP2	O14757	CHEK1	S1313	E1312Q	1312	Missense	proximal	-1	no	9.915	10.021	EPSD	COSMIC;CCLE	5.604	Up-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q08AD1	CAMSAP2	O14757	CHEK1	S1313	L1318V	1318	Missense	distal	5	no	9.915	10.073	EPSD	COSMIC	5.604	Up-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q9Y3Y2	CHTOP	O14757	CHEK1	T212	A207T	207	Missense	distal	-5	no	3.459	7.319	PhosphoSitePlus	COSMIC;GDSC;CCLE	5.604	Gain
CAMK_CAMKL_CHK1_CHEK1_ST	Q9Y3Y2	CHTOP	O14757	CHEK1	S225	K226Q	226	Missense	proximal	1	no	9.106	9.114	EPSD	COSMIC	5.604	Up-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q9Y3Y2	CHTOP	O14757	CHEK1	S225	S225L	225	Missense	central	0	yes	9.106	0.000	EPSD	COSMIC	5.604	Loss
CAMK_CAMKL_CHK1_CHEK1_ST	P30305	CDC25B	O14757	CHEK1	T167	V162L	162	Missense	distal	-5	no	7.142	10.619	EPSD	COSMIC	5.604	Up-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	P30305	CDC25B	O14757	CHEK1	S178	A184V	184	Missense	distal	6	no	10.481	10.368	EPSD	COSMIC	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	P30305	CDC25B	O14757	CHEK1	S178	R175Q	175	Missense	distal	-3	no	10.481	3.274	EPSD	COSMIC;GDSC	5.604	Loss
CAMK_CAMKL_CHK1_CHEK1_ST	P30305	CDC25B	O14757	CHEK1	S178	S178N	178	Missense	central	0	yes	10.481	0.000	EPSD	COSMIC;GDSC;CCLE	5.604	Loss
CAMK_CAMKL_CHK1_CHEK1_ST	P30305	CDC25B	O14757	CHEK1	S230	L237H	237	Missense	distal	7	no	9.172	8.980	EPSD;PhosphoSitePlus	COSMIC	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	P30305	CDC25B	O14757	CHEK1	S230	S230F	230	Missense	central	0	yes	9.172	0.000	EPSD;PhosphoSitePlus	COSMIC	5.604	Loss
CAMK_CAMKL_CHK1_CHEK1_ST	P30305	CDC25B	O14757	CHEK1	S323	S323N	323	Missense	central	0	yes	8.657	0.000	EPSD	COSMIC	5.604	Loss
CAMK_CAMKL_CHK1_CHEK1_ST	P30305	CDC25B	O14757	CHEK1	S323	P325L	325	Missense	proximal	2	no	8.657	8.339	EPSD	COSMIC	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	P30305	CDC25B	O14757	CHEK1	S323	R320G	320	Missense	distal	-3	no	8.657	0.882	EPSD	COSMIC	5.604	Loss
CAMK_CAMKL_CHK1_CHEK1_ST	P30305	CDC25B	O14757	CHEK1	S323	S321F	321	Missense	proximal	-2	no	8.657	8.947	EPSD	COSMIC	5.604	Up-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	P30305	CDC25B	O14757	CHEK1	S323	R330Q	330	Missense	distal	7	no	8.657	8.812	EPSD	COSMIC	5.604	Up-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	P30305	CDC25B	O14757	CHEK1	S323	P322L	322	Missense	proximal	-1	no	8.657	8.471	EPSD	COSMIC	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	P30305	CDC25B	O14757	CHEK1	S323	R317W	317	Missense	distal	-6	no	8.657	8.977	EPSD	COSMIC	5.604	Up-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	P30305	CDC25B	O14757	CHEK1	S353	R352Q	352	Missense	proximal	-1	no	9.037	9.052	EPSD	COSMIC	5.604	Up-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	P30305	CDC25B	O14757	CHEK1	S353	R350T	350	Missense	distal	-3	no	9.037	-11.532	EPSD	COSMIC	5.604	Loss
CAMK_CAMKL_CHK1_CHEK1_ST	P30305	CDC25B	O14757	CHEK1	T355	R352Q	352	Missense	distal	-3	no	7.993	0.787	EPSD	COSMIC	5.604	Loss
CAMK_CAMKL_CHK1_CHEK1_ST	P30305	CDC25B	O14757	CHEK1	T355	R350T	350	Missense	distal	-5	no	7.993	8.914	EPSD	COSMIC	5.604	Up-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	P30305	CDC25B	O14757	CHEK1	S375	S373N	373	Missense	proximal	-2	no	9.149	9.338	EPSD	COSMIC	5.604	Up-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	P30305	CDC25B	O14757	CHEK1	S375	R372C	372	Missense	distal	-3	no	9.149	1.058	EPSD	COSMIC	5.604	Loss
CAMK_CAMKL_CHK1_CHEK1_ST	P30305	CDC25B	O14757	CHEK1	S375	V370I	370	Missense	distal	-5	no	9.149	10.595	EPSD	COSMIC;GDSC;CCLE	5.604	Up-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	P30305	CDC25B	O14757	CHEK1	S375	E380K	380	Missense	distal	5	no	9.149	9.084	EPSD	COSMIC	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	P30305	CDC25B	O14757	CHEK1	T561	R568Q	568	Missense	distal	7	no	5.539	5.694	EPSD	COSMIC	5.604	Gain
CAMK_CAMKL_CHK1_CHEK1_ST	P30305	CDC25B	O14757	CHEK1	T561	K560R	560	Missense	proximal	-1	no	5.539	5.687	EPSD	COSMIC	5.604	Gain
CAMK_CAMKL_CHK1_CHEK1_ST	P30305	CDC25B	O14757	CHEK1	S563	R562W	562	Missense	proximal	-1	no	6.380	6.497	PhosphoSitePlus;EPSD	COSMIC	5.604	Up-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	P30305	CDC25B	O14757	CHEK1	S563	T556I	556	Missense	distal	-7	no	6.380	6.604	PhosphoSitePlus;EPSD	COSMIC	5.604	Up-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	P30305	CDC25B	O14757	CHEK1	S563	R568Q	568	Missense	distal	5	no	6.380	6.455	PhosphoSitePlus;EPSD	COSMIC	5.604	Up-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	P30305	CDC25B	O14757	CHEK1	S563	R570W	570	Missense	distal	7	no	6.380	5.878	PhosphoSitePlus;EPSD	COSMIC	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	P30305	CDC25B	O14757	CHEK1	S563	R558H	558	Missense	distal	-5	no	6.380	3.915	PhosphoSitePlus;EPSD	COSMIC	5.604	Loss
CAMK_CAMKL_CHK1_CHEK1_ST	P30305	CDC25B	O14757	CHEK1	S563	K560R	560	Missense	distal	-3	no	6.380	10.205	PhosphoSitePlus;EPSD	COSMIC	5.604	Up-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	P30305	CDC25B	O14757	CHEK1	S563	R570L	570	Missense	distal	7	no	6.380	6.279	PhosphoSitePlus;EPSD	COSMIC	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q5JSZ5	PRRC2B	O14757	CHEK1	S37	P41L	41	Missense	distal	4	no	5.727	5.623	EPSD	COSMIC	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q5JSZ5	PRRC2B	O14757	CHEK1	S104	A103T	103	Missense	proximal	-1	no	5.996	5.867	EPSD	COSMIC	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q5JSZ5	PRRC2B	O14757	CHEK1	S120	G114S	114	Missense	distal	-6	no	8.802	8.764	EPSD	COSMIC	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q5JSZ5	PRRC2B	O14757	CHEK1	S166	S166F	166	Missense	central	0	yes	9.677	0.000	PhosphoSitePlus	COSMIC	5.604	Loss
CAMK_CAMKL_CHK1_CHEK1_ST	Q5JSZ5	PRRC2B	O14757	CHEK1	S166	L165F	165	Missense	proximal	-1	no	9.677	9.690	PhosphoSitePlus	COSMIC;GDSC;CCLE	5.604	Up-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q5JSZ5	PRRC2B	O14757	CHEK1	S236	G231D	231	Missense	distal	-5	no	12.090	11.268	EPSD	COSMIC	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q5JSZ5	PRRC2B	O14757	CHEK1	S236	G240V	240	Missense	distal	4	no	12.090	12.134	EPSD	COSMIC	5.604	Up-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q5JSZ5	PRRC2B	O14757	CHEK1	S236	G238E	238	Missense	proximal	2	no	12.090	12.704	EPSD	COSMIC	5.604	Up-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q5JSZ5	PRRC2B	O14757	CHEK1	S266	V261I	261	Missense	distal	-5	no	4.527	5.973	EPSD	COSMIC	5.604	Gain
CAMK_CAMKL_CHK1_CHEK1_ST	Q5JSZ5	PRRC2B	O14757	CHEK1	T736	P737S	737	Missense	proximal	1	no	6.742	6.779	EPSD	COSMIC;GDSC;CCLE	5.604	Up-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q5JSZ5	PRRC2B	O14757	CHEK1	T736	P741H	741	Missense	distal	5	no	6.742	6.736	EPSD	COSMIC	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q5JSZ5	PRRC2B	O14757	CHEK1	S778	M772T	772	Missense	distal	-6	no	7.062	7.070	EPSD	COSMIC	5.604	Up-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q5JSZ5	PRRC2B	O14757	CHEK1	S778	R773P	773	Missense	distal	-5	no	7.062	5.332	EPSD	COSMIC;GDSC;CCLE	5.604	Loss
CAMK_CAMKL_CHK1_CHEK1_ST	Q5JSZ5	PRRC2B	O14757	CHEK1	T895	G894E	894	Missense	proximal	-1	no	6.965	6.857	EPSD	COSMIC	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q5JSZ5	PRRC2B	O14757	CHEK1	T895	R888L	888	Missense	distal	-7	no	6.965	6.340	EPSD	COSMIC	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q5JSZ5	PRRC2B	O14757	CHEK1	S1153	G1156E	1156	Missense	distal	3	no	4.071	5.618	EPSD	COSMIC	5.604	Gain
CAMK_CAMKL_CHK1_CHEK1_ST	Q5JSZ5	PRRC2B	O14757	CHEK1	S1422	V1427M	1427	Missense	distal	5	no	9.656	9.629	EPSD	COSMIC	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q5JSZ5	PRRC2B	O14757	CHEK1	S1458	T1463M	1463	Missense	distal	5	no	10.513	10.623	EPSD	COSMIC;GDSC;CCLE	5.604	Up-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q5JSZ5	PRRC2B	O14757	CHEK1	S1458	R1455C	1455	Missense	distal	-3	no	10.513	2.422	EPSD	COSMIC	5.604	Loss
CAMK_CAMKL_CHK1_CHEK1_ST	Q5JSZ5	PRRC2B	O14757	CHEK1	S1458	R1455P	1455	Missense	distal	-3	no	10.513	3.376	EPSD	COSMIC	5.604	Loss
CAMK_CAMKL_CHK1_CHEK1_ST	Q5JSZ5	PRRC2B	O14757	CHEK1	S1470	T1463M	1463	Missense	distal	-7	no	7.134	7.600	EPSD	COSMIC;GDSC;CCLE	5.604	Up-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q5JSZ5	PRRC2B	O14757	CHEK1	S1470	P1471Q	1471	Missense	proximal	1	no	7.134	7.205	EPSD	COSMIC	5.604	Up-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q5JSZ5	PRRC2B	O14757	CHEK1	S1508	P1504S	1504	Missense	distal	-4	no	6.461	6.224	EPSD	COSMIC	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q5JSZ5	PRRC2B	O14757	CHEK1	S1595	L1594V	1594	Missense	proximal	-1	no	8.712	8.706	EPSD	COSMIC	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q5JSZ5	PRRC2B	O14757	CHEK1	S1595	R1592L	1592	Missense	distal	-3	no	8.712	-9.835	EPSD	COSMIC	5.604	Loss
CAMK_CAMKL_CHK1_CHEK1_ST	Q5JSZ5	PRRC2B	O14757	CHEK1	S1683	E1678K	1678	Missense	distal	-5	no	4.145	6.706	EPSD	COSMIC	5.604	Gain
CAMK_CAMKL_CHK1_CHEK1_ST	Q5JSZ5	PRRC2B	O14757	CHEK1	S1754	A1757V	1757	Missense	distal	3	no	9.353	9.598	EPSD	COSMIC	5.604	Up-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q5JSZ5	PRRC2B	O14757	CHEK1	S1803	G1800R	1800	Missense	distal	-3	no	-0.947	6.828	EPSD	COSMIC	5.604	Gain
CAMK_CAMKL_CHK1_CHEK1_ST	Q5JSZ5	PRRC2B	O14757	CHEK1	S1858	R1860C	1860	Missense	proximal	2	no	6.978	6.712	EPSD	COSMIC	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q5JSZ5	PRRC2B	O14757	CHEK1	S1858	A1862D	1862	Missense	distal	4	no	6.978	6.835	EPSD	COSMIC	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q5JSZ5	PRRC2B	O14757	CHEK1	S1858	K1861N	1861	Missense	distal	3	no	6.978	7.175	EPSD	COSMIC	5.604	Up-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q5JSZ5	PRRC2B	O14757	CHEK1	S2085	I2091L	2091	Missense	distal	6	no	11.961	12.328	EPSD	COSMIC	5.604	Up-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q5JSZ5	PRRC2B	O14757	CHEK1	S2085	R2082Q	2082	Missense	distal	-3	no	11.961	4.754	EPSD	COSMIC	5.604	Loss
CAMK_CAMKL_CHK1_CHEK1_ST	Q5JSZ5	PRRC2B	O14757	CHEK1	S2085	P2089S	2089	Missense	distal	4	no	11.961	11.821	EPSD	COSMIC	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q5JSZ5	PRRC2B	O14757	CHEK1	S2085	S2085F	2085	Missense	central	0	yes	11.961	0.000	EPSD	COSMIC	5.604	Loss
CAMK_CAMKL_CHK1_CHEK1_ST	Q5JSZ5	PRRC2B	O14757	CHEK1	S2103	P2100H	2100	Missense	distal	-3	no	6.503	7.830	EPSD	COSMIC	5.604	Up-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q5JSZ5	PRRC2B	O14757	CHEK1	S2103	L2098M	2098	Missense	distal	-5	no	6.503	2.129	EPSD	COSMIC	5.604	Loss
CAMK_CAMKL_CHK1_CHEK1_ST	Q5JSZ5	PRRC2B	O14757	CHEK1	S2161	S2165G	2165	Missense	distal	4	no	9.690	9.757	EPSD	COSMIC	5.604	Up-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q5JSZ5	PRRC2B	O14757	CHEK1	S2161	P2159S	2159	Missense	proximal	-2	no	9.690	9.406	EPSD	COSMIC;GDSC	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q5JSZ5	PRRC2B	O14757	CHEK1	S2161	Y2157H	2157	Missense	distal	-4	no	9.690	9.978	EPSD	COSMIC	5.604	Up-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q5JSZ5	PRRC2B	O14757	CHEK1	S2161	R2158M	2158	Missense	distal	-3	no	9.690	4.542	EPSD	COSMIC	5.604	Loss
CAMK_CAMKL_CHK1_CHEK1_ST	P02545	LMNA	O14757	CHEK1	T10	G13A	13	Missense	distal	3	no	7.061	7.243	EPSD	COSMIC	5.604	Up-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	P02545	LMNA	O14757	CHEK1	S51	E55K	55	Missense	distal	4	no	9.757	9.751	EPSD	COSMIC	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	P02545	LMNA	O14757	CHEK1	T64	L61I	61	Missense	distal	-3	no	-3.900	5.889	EPSD	COSMIC;GDSC;CCLE	5.604	Gain
CAMK_CAMKL_CHK1_CHEK1_ST	P02545	LMNA	O14757	CHEK1	S75	K78E	78	Missense	distal	3	no	10.848	11.664	EPSD	COSMIC	5.604	Up-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	P02545	LMNA	O14757	CHEK1	S75	E73K	73	Missense	proximal	-2	no	10.848	10.705	EPSD	COSMIC	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	P02545	LMNA	O14757	CHEK1	T199	Q198K	198	Missense	proximal	-1	no	7.521	7.357	EPSD	COSMIC	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	P02545	LMNA	O14757	CHEK1	T199	L197M	197	Missense	proximal	-2	no	7.521	7.558	EPSD	COSMIC	5.604	Up-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	P02545	LMNA	O14757	CHEK1	T224	N231D	231	Missense	distal	7	no	10.611	10.772	EPSD	COSMIC	5.604	Up-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	P02545	LMNA	O14757	CHEK1	T224	V227M	227	Missense	distal	3	no	10.611	10.185	EPSD	COSMIC	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	P02545	LMNA	O14757	CHEK1	T224	R225Q	225	Missense	proximal	1	no	10.611	10.619	EPSD	COSMIC	5.604	Up-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	P02545	LMNA	O14757	CHEK1	S268	L271P	271	Missense	distal	3	no	11.876	12.640	EPSD	COSMIC	5.604	Up-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	P02545	LMNA	O14757	CHEK1	S268	L271R	271	Missense	distal	3	no	11.876	12.308	EPSD	COSMIC	5.604	Up-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	P02545	LMNA	O14757	CHEK1	S268	Y267C	267	Missense	proximal	-1	no	11.876	11.743	EPSD	COSMIC	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	P02545	LMNA	O14757	CHEK1	S268	D272Y	272	Missense	distal	4	no	11.876	12.000	EPSD	COSMIC	5.604	Up-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	P02545	LMNA	O14757	CHEK1	S268	A269V	269	Missense	proximal	1	no	11.876	11.852	EPSD	COSMIC	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	P02545	LMNA	O14757	CHEK1	S301	R298L	298	Missense	distal	-3	no	10.314	-8.232	EPSD	COSMIC	5.604	Loss
CAMK_CAMKL_CHK1_CHEK1_ST	P02545	LMNA	O14757	CHEK1	S301	R298C	298	Missense	distal	-3	no	10.314	2.223	EPSD	COSMIC;GDSC;CCLE	5.604	Loss
CAMK_CAMKL_CHK1_CHEK1_ST	P02545	LMNA	O14757	CHEK1	S301	R296C	296	Missense	distal	-5	no	10.314	9.636	EPSD	COSMIC	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	P02545	LMNA	O14757	CHEK1	S307	Q310K	310	Missense	distal	3	no	7.332	6.916	PhosphoSitePlus	COSMIC	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	P02545	LMNA	O14757	CHEK1	S392	L389R	389	Missense	distal	-3	no	-5.953	12.593	EPSD	COSMIC	5.604	Gain
CAMK_CAMKL_CHK1_CHEK1_ST	P02545	LMNA	O14757	CHEK1	S404	S403F	403	Missense	proximal	-1	no	7.892	8.166	EPSD	COSMIC	5.604	Up-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	P02545	LMNA	O14757	CHEK1	S404	R401W	401	Missense	distal	-3	no	7.892	-25.712	EPSD	COSMIC	5.604	Loss
CAMK_CAMKL_CHK1_CHEK1_ST	P02545	LMNA	O14757	CHEK1	T548	D555Y	555	Missense	distal	7	no	12.081	11.175	EPSD	COSMIC	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	P02545	LMNA	O14757	CHEK1	T585	S583A	583	Missense	proximal	-2	no	6.830	6.945	EPSD	COSMIC	5.604	Up-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	P02545	LMNA	O14757	CHEK1	T585	N580K	580	Missense	distal	-5	no	6.830	7.724	EPSD	COSMIC	5.604	Up-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	P02545	LMNA	O14757	CHEK1	T585	C588W	588	Missense	distal	3	no	6.830	7.640	EPSD	COSMIC	5.604	Up-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	P02545	LMNA	O14757	CHEK1	S657	I663M	663	Missense	distal	6	no	10.155	10.514	EPSD	COSMIC	5.604	Up-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	P02545	LMNA	O14757	CHEK1	S657	Q659L	659	Missense	proximal	2	no	10.155	9.328	EPSD	COSMIC	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	P02545	LMNA	O14757	CHEK1	S657	R654Q	654	Missense	distal	-3	no	10.155	2.948	EPSD	COSMIC	5.604	Loss
CAMK_CAMKL_CHK1_CHEK1_ST	O15151	MDM4	O14757	CHEK1	S127	Q133E	133	Missense	distal	6	no	6.492	6.141	EPSD	COSMIC	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	O15151	MDM4	O14757	CHEK1	T150	S144L	144	Missense	distal	-6	no	9.666	9.690	EPSD	COSMIC	5.604	Up-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	O15151	MDM4	O14757	CHEK1	T150	P156H	156	Missense	distal	6	no	9.666	9.422	EPSD	COSMIC	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	O15151	MDM4	O14757	CHEK1	T150	I155V	155	Missense	distal	5	no	9.666	9.724	EPSD	COSMIC	5.604	Up-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	O15151	MDM4	O14757	CHEK1	T150	R147K	147	Missense	distal	-3	no	9.666	5.840	EPSD	COSMIC	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	O15151	MDM4	O14757	CHEK1	S342	L337V	337	Missense	distal	-5	no	8.442	4.965	PhosphoSitePlus;EPSD	COSMIC	5.604	Loss
CAMK_CAMKL_CHK1_CHEK1_ST	O15151	MDM4	O14757	CHEK1	S342	S342F	342	Missense	central	0	yes	8.442	0.000	PhosphoSitePlus;EPSD	COSMIC	5.604	Loss
CAMK_CAMKL_CHK1_CHEK1_ST	O15151	MDM4	O14757	CHEK1	S367	S367L	367	Missense	central	0	yes	8.466	0.000	EPSD;PhosphoSitePlus	COSMIC;GDSC;CCLE	5.604	Loss
CAMK_CAMKL_CHK1_CHEK1_ST	O15151	MDM4	O14757	CHEK1	S367	V370F	370	Missense	distal	3	no	8.466	8.315	EPSD;PhosphoSitePlus	COSMIC	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	O15151	MDM4	O14757	CHEK1	S367	T365I	365	Missense	proximal	-2	no	8.466	8.340	EPSD;PhosphoSitePlus	COSMIC	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	O15151	MDM4	O14757	CHEK1	S367	R364G	364	Missense	distal	-3	no	8.466	0.691	EPSD;PhosphoSitePlus	COSMIC	5.604	Loss
CAMK_CAMKL_CHK1_CHEK1_ST	O95625	ZBTB11	O14757	CHEK1	S130	I129L	129	Missense	proximal	-1	no	9.242	9.386	EPSD	COSMIC	5.604	Up-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	O95625	ZBTB11	O14757	CHEK1	S130	P128S	128	Missense	proximal	-2	no	9.242	8.958	EPSD	COSMIC	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	O95625	ZBTB11	O14757	CHEK1	S511	G515V	515	Missense	distal	4	no	9.371	9.415	EPSD;PhosphoSitePlus	COSMIC	5.604	Up-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	O95625	ZBTB11	O14757	CHEK1	S537	Q540E	540	Missense	distal	3	no	5.926	6.326	PhosphoSitePlus;EPSD	COSMIC	5.604	Up-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	O95625	ZBTB11	O14757	CHEK1	S665	R667L	667	Missense	proximal	2	no	6.915	6.616	EPSD	COSMIC	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	O95625	ZBTB11	O14757	CHEK1	S665	R658K	658	Missense	distal	-7	no	6.915	8.095	EPSD	COSMIC	5.604	Up-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	O95625	ZBTB11	O14757	CHEK1	T909	V915F	915	Missense	distal	6	no	7.303	7.430	EPSD	COSMIC	5.604	Up-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	O95625	ZBTB11	O14757	CHEK1	T909	R912Q	912	Missense	distal	3	no	7.303	8.366	EPSD	COSMIC	5.604	Up-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	O95625	ZBTB11	O14757	CHEK1	T909	R903H	903	Missense	distal	-6	no	7.303	7.413	EPSD	COSMIC	5.604	Up-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q9UPP1	PHF8	O14757	CHEK1	S104	K106N	106	Missense	proximal	2	no	9.702	9.293	EPSD	COSMIC	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q9UPP1	PHF8	O14757	CHEK1	S105	K106N	106	Missense	proximal	1	no	9.913	9.884	EPSD	COSMIC	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q9UPP1	PHF8	O14757	CHEK1	S105	K112M	112	Missense	distal	7	no	9.913	9.730	EPSD	COSMIC	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q9UPP1	PHF8	O14757	CHEK1	T118	P115R	115	Missense	distal	-3	no	-1.392	5.744	EPSD	COSMIC	5.604	Gain
CAMK_CAMKL_CHK1_CHEK1_ST	Q9UPP1	PHF8	O14757	CHEK1	S621	T614A	614	Missense	distal	-7	no	4.821	6.137	EPSD	COSMIC	5.604	Gain
CAMK_CAMKL_CHK1_CHEK1_ST	Q9UPP1	PHF8	O14757	CHEK1	S826	E831D	831	Missense	distal	5	no	6.625	6.627	EPSD	COSMIC	5.604	Up-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q9UPP1	PHF8	O14757	CHEK1	S826	W822C	822	Missense	distal	-4	no	6.625	7.014	EPSD	COSMIC	5.604	Up-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q9UPP1	PHF8	O14757	CHEK1	S826	P819L	819	Missense	distal	-7	no	6.625	6.411	EPSD	COSMIC	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q9UPP1	PHF8	O14757	CHEK1	S840	D839N	839	Missense	proximal	-1	no	5.661	5.750	EPSD	COSMIC	5.604	Up-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q9UPP1	PHF8	O14757	CHEK1	S840	D836G	836	Missense	distal	-4	no	5.661	5.625	EPSD	COSMIC	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q9UPP1	PHF8	O14757	CHEK1	S874	P878Q	878	Missense	distal	4	no	6.172	6.083	EPSD	COSMIC	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q9UPP1	PHF8	O14757	CHEK1	S874	A877S	877	Missense	distal	3	no	6.172	6.078	EPSD	COSMIC	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q9UPP1	PHF8	O14757	CHEK1	S874	R867C	867	Missense	distal	-7	no	6.172	5.444	EPSD	COSMIC	5.604	Loss
CAMK_CAMKL_CHK1_CHEK1_ST	Q9UPP1	PHF8	O14757	CHEK1	T900	T907K	907	Missense	distal	7	no	5.875	6.110	EPSD	COSMIC	5.604	Up-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q9UPP1	PHF8	O14757	CHEK1	T900	G899R	899	Missense	proximal	-1	no	5.875	5.858	EPSD	COSMIC	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q9UPP1	PHF8	O14757	CHEK1	T900	R897C	897	Missense	distal	-3	no	5.875	-2.217	EPSD	COSMIC	5.604	Loss
CAMK_CAMKL_CHK1_CHEK1_ST	Q9UPP1	PHF8	O14757	CHEK1	T900	P895L	895	Missense	distal	-5	no	5.875	10.581	EPSD	COSMIC	5.604	Up-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q9UPP1	PHF8	O14757	CHEK1	T900	R894H	894	Missense	distal	-6	no	5.875	5.984	EPSD	COSMIC	5.604	Up-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q9UPP1	PHF8	O14757	CHEK1	S904	T907K	907	Missense	distal	3	no	10.335	11.123	PhosphoSitePlus	COSMIC	5.604	Up-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q9UPP1	PHF8	O14757	CHEK1	S904	G899R	899	Missense	distal	-5	no	10.335	10.501	PhosphoSitePlus	COSMIC	5.604	Up-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q9UPP1	PHF8	O14757	CHEK1	S904	R897C	897	Missense	distal	-7	no	10.335	9.607	PhosphoSitePlus	COSMIC	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q9UPP1	PHF8	O14757	CHEK1	S1021	L1015F	1015	Missense	distal	-6	no	11.227	11.476	EPSD	COSMIC	5.604	Up-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q9UPP1	PHF8	O14757	CHEK1	S1021	Q1017L	1017	Missense	distal	-4	no	11.227	10.811	EPSD	COSMIC	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q9UPP1	PHF8	O14757	CHEK1	S1021	R1018K	1018	Missense	distal	-3	no	11.227	7.401	EPSD	COSMIC	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q9H0H5	RACGAP1	O14757	CHEK1	T63	D69N	69	Missense	distal	6	no	8.710	9.028	EPSD	COSMIC	5.604	Up-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q9H0H5	RACGAP1	O14757	CHEK1	S185	T186A	186	Missense	proximal	1	no	6.899	6.910	EPSD	COSMIC	5.604	Up-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q9H0H5	RACGAP1	O14757	CHEK1	S185	K178N	178	Missense	distal	-7	no	6.899	5.441	EPSD	COSMIC	5.604	Loss
CAMK_CAMKL_CHK1_CHEK1_ST	Q9H0H5	RACGAP1	O14757	CHEK1	S185	E181G	181	Missense	distal	-4	no	6.899	6.722	EPSD	COSMIC	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q9H0H5	RACGAP1	O14757	CHEK1	T186	T186A	186	Missense	central	0	yes	9.475	0.000	EPSD	COSMIC	5.604	Loss
CAMK_CAMKL_CHK1_CHEK1_ST	Q9H0H5	RACGAP1	O14757	CHEK1	T186	E181G	181	Missense	distal	-5	no	9.475	10.697	EPSD	COSMIC	5.604	Up-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q9H0H5	RACGAP1	O14757	CHEK1	S187	T186A	186	Missense	proximal	-1	no	10.203	10.332	EPSD	COSMIC	5.604	Up-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q9H0H5	RACGAP1	O14757	CHEK1	S187	E181G	181	Missense	distal	-6	no	10.203	10.363	EPSD	COSMIC	5.604	Up-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q9H0H5	RACGAP1	O14757	CHEK1	S203	R202H	202	Missense	proximal	-1	no	6.016	6.142	PhosphoSitePlus	COSMIC	5.604	Up-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q9H0H5	RACGAP1	O14757	CHEK1	T272	T277M	277	Missense	distal	5	no	7.235	7.345	EPSD	COSMIC	5.604	Up-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q9H0H5	RACGAP1	O14757	CHEK1	S299	R306W	306	Missense	distal	7	no	7.389	6.888	EPSD	COSMIC	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q9H0H5	RACGAP1	O14757	CHEK1	T405	R402I	402	Missense	distal	-3	no	7.444	-1.314	EPSD	COSMIC	5.604	Loss
CAMK_CAMKL_CHK1_CHEK1_ST	Q9H0H5	RACGAP1	O14757	CHEK1	T405	R402T	402	Missense	distal	-3	no	7.444	-13.125	EPSD	COSMIC	5.604	Loss
CAMK_CAMKL_CHK1_CHEK1_ST	Q9H0H5	RACGAP1	O14757	CHEK1	S590	P589F	589	Missense	proximal	-1	no	8.547	8.373	EPSD	COSMIC	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q9H0H5	RACGAP1	O14757	CHEK1	S600	R599C	599	Missense	proximal	-1	no	9.329	9.364	EPSD	COSMIC	5.604	Up-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q9UMR2	DDX19B	O14757	CHEK1	S93	Y89C	89	Missense	distal	-4	no	7.232	7.343	PhosphoSitePlus	COSMIC	5.604	Up-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q9UMR2	DDX19B	O14757	CHEK1	S154	V156A	156	Missense	proximal	2	no	5.204	5.767	EPSD	COSMIC	5.604	Gain
CAMK_CAMKL_CHK1_CHEK1_ST	Q9UMR2	DDX19B	O14757	CHEK1	S354	G357C	357	Missense	distal	3	no	8.920	8.058	EPSD	COSMIC	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q86UE8	TLK2	O14757	CHEK1	S44	S41C	41	Missense	distal	-3	no	4.321	5.925	EPSD	COSMIC	5.604	Gain
CAMK_CAMKL_CHK1_CHEK1_ST	Q86UE8	TLK2	O14757	CHEK1	S111	P106L	106	Missense	distal	-5	no	1.892	6.599	EPSD	COSMIC	5.604	Gain
CAMK_CAMKL_CHK1_CHEK1_ST	Q86UE8	TLK2	O14757	CHEK1	S196	K199E	199	Missense	distal	3	no	5.326	6.142	EPSD	COSMIC	5.604	Gain
CAMK_CAMKL_CHK1_CHEK1_ST	Q86UE8	TLK2	O14757	CHEK1	T268	R262Q	262	Missense	distal	-6	no	13.094	13.176	EPSD	COSMIC;GDSC;CCLE	5.604	Up-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q86UE8	TLK2	O14757	CHEK1	S686	Q685H	685	Missense	proximal	-1	no	7.842	7.952	PhosphoSitePlus	COSMIC	5.604	Up-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q86UE8	TLK2	O14757	CHEK1	S686	G682V	682	Missense	distal	-4	no	7.842	7.808	PhosphoSitePlus	COSMIC	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q92974	ARHGEF2	O14757	CHEK1	T103	A104T	104	Missense	proximal	1	no	9.192	9.182	EPSD	COSMIC;CCLE	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q92974	ARHGEF2	O14757	CHEK1	T103	K100M	100	Missense	distal	-3	no	9.192	7.869	EPSD	COSMIC	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q92974	ARHGEF2	O14757	CHEK1	T103	A96V	96	Missense	distal	-7	no	9.192	8.536	EPSD	COSMIC	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q92974	ARHGEF2	O14757	CHEK1	S122	Y125S	125	Missense	distal	3	no	6.578	7.806	EPSD	COSMIC	5.604	Up-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q92974	ARHGEF2	O14757	CHEK1	S122	D128Y	128	Missense	distal	6	no	6.578	7.503	EPSD	COSMIC	5.604	Up-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q92974	ARHGEF2	O14757	CHEK1	S122	D128E	128	Missense	distal	6	no	6.578	6.492	EPSD	COSMIC	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q92974	ARHGEF2	O14757	CHEK1	S122	S122L	122	Missense	central	0	yes	6.578	0.000	EPSD	COSMIC	5.604	Loss
CAMK_CAMKL_CHK1_CHEK1_ST	Q92974	ARHGEF2	O14757	CHEK1	S142	S137F	137	Missense	distal	-5	no	6.650	6.274	EPSD	COSMIC	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q92974	ARHGEF2	O14757	CHEK1	S142	R138S	138	Missense	distal	-4	no	6.650	6.342	EPSD	COSMIC	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q92974	ARHGEF2	O14757	CHEK1	S142	R141S	141	Missense	proximal	-1	no	6.650	6.489	EPSD	COSMIC	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q92974	ARHGEF2	O14757	CHEK1	S142	R141C	141	Missense	proximal	-1	no	6.650	6.685	EPSD	COSMIC	5.604	Up-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q92974	ARHGEF2	O14757	CHEK1	S142	R141L	141	Missense	proximal	-1	no	6.650	6.749	EPSD	COSMIC	5.604	Up-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q92974	ARHGEF2	O14757	CHEK1	S172	S174P	174	Missense	proximal	2	no	10.777	10.701	PhosphoSitePlus	COSMIC	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q92974	ARHGEF2	O14757	CHEK1	S172	R168L	168	Missense	distal	-4	no	10.777	10.522	PhosphoSitePlus	COSMIC	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q92974	ARHGEF2	O14757	CHEK1	S172	T175K	175	Missense	distal	3	no	10.777	11.565	PhosphoSitePlus	COSMIC	5.604	Up-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q92974	ARHGEF2	O14757	CHEK1	T184	R183S	183	Missense	proximal	-1	no	10.615	10.454	EPSD	COSMIC	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q92974	ARHGEF2	O14757	CHEK1	T184	S186F	186	Missense	proximal	2	no	10.615	10.471	EPSD	COSMIC	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q92974	ARHGEF2	O14757	CHEK1	S186	R183S	183	Missense	distal	-3	no	7.012	-2.683	EPSD	COSMIC	5.604	Loss
CAMK_CAMKL_CHK1_CHEK1_ST	Q92974	ARHGEF2	O14757	CHEK1	S186	S186F	186	Missense	central	0	yes	7.012	0.000	EPSD	COSMIC	5.604	Loss
CAMK_CAMKL_CHK1_CHEK1_ST	Q92974	ARHGEF2	O14757	CHEK1	T258	R259S	259	Missense	proximal	1	no	6.469	6.443	EPSD	COSMIC	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q92974	ARHGEF2	O14757	CHEK1	T258	M257I	257	Missense	proximal	-1	no	6.469	6.376	EPSD	COSMIC	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q92974	ARHGEF2	O14757	CHEK1	T455	T455K	455	Missense	central	0	yes	7.432	0.000	EPSD	COSMIC	5.604	Loss
CAMK_CAMKL_CHK1_CHEK1_ST	Q92974	ARHGEF2	O14757	CHEK1	T455	M449I	449	Missense	distal	-6	no	7.432	7.369	EPSD	COSMIC	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q92974	ARHGEF2	O14757	CHEK1	S645	R642C	642	Missense	distal	-3	no	10.882	2.790	EPSD	COSMIC	5.604	Loss
CAMK_CAMKL_CHK1_CHEK1_ST	Q92974	ARHGEF2	O14757	CHEK1	S645	S645F	645	Missense	central	0	yes	10.882	0.000	EPSD	COSMIC	5.604	Loss
CAMK_CAMKL_CHK1_CHEK1_ST	Q92974	ARHGEF2	O14757	CHEK1	S691	E688K	688	Missense	distal	-3	no	3.401	6.664	EPSD	COSMIC	5.604	Gain
CAMK_CAMKL_CHK1_CHEK1_ST	Q92974	ARHGEF2	O14757	CHEK1	S719	S721C	721	Missense	proximal	2	no	10.291	9.930	EPSD	COSMIC	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q92974	ARHGEF2	O14757	CHEK1	S719	D718H	718	Missense	proximal	-1	no	10.291	10.448	EPSD	COSMIC	5.604	Up-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q92974	ARHGEF2	O14757	CHEK1	S782	A780S	780	Missense	proximal	-2	no	11.920	11.806	EPSD	COSMIC	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q92974	ARHGEF2	O14757	CHEK1	S782	R783Q	783	Missense	proximal	1	no	11.920	11.929	EPSD	COSMIC;CCLE	5.604	Up-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q92974	ARHGEF2	O14757	CHEK1	S886	R885W	885	Missense	proximal	-1	no	10.562	10.680	EPSD	COSMIC	5.604	Up-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q92974	ARHGEF2	O14757	CHEK1	S886	R883Q	883	Missense	distal	-3	no	10.562	3.355	EPSD	COSMIC	5.604	Loss
CAMK_CAMKL_CHK1_CHEK1_ST	Q92974	ARHGEF2	O14757	CHEK1	S886	R884C	884	Missense	proximal	-2	no	10.562	10.511	EPSD	COSMIC	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q92974	ARHGEF2	O14757	CHEK1	S886	R884H	884	Missense	proximal	-2	no	10.562	10.627	EPSD	COSMIC	5.604	Up-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q92974	ARHGEF2	O14757	CHEK1	S886	R885C	885	Missense	proximal	-1	no	10.562	10.597	EPSD	COSMIC;CCLE	5.604	Up-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q92974	ARHGEF2	O14757	CHEK1	S886	L887F	887	Missense	proximal	1	no	10.562	10.566	EPSD	COSMIC	5.604	Up-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q92974	ARHGEF2	O14757	CHEK1	S886	P882L	882	Missense	distal	-4	no	10.562	10.378	EPSD	COSMIC	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q92974	ARHGEF2	O14757	CHEK1	S886	P888S	888	Missense	proximal	2	no	10.562	10.639	EPSD	COSMIC	5.604	Up-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q92974	ARHGEF2	O14757	CHEK1	S886	P888L	888	Missense	proximal	2	no	10.562	10.245	EPSD	COSMIC	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q92974	ARHGEF2	O14757	CHEK1	S960	L955V	955	Missense	distal	-5	no	6.584	3.107	EPSD	COSMIC	5.604	Loss
CAMK_CAMKL_CHK1_CHEK1_ST	Q9Y570	PPME1	O14757	CHEK1	S15	L13I	13	Missense	proximal	-2	no	13.534	13.557	PhosphoSitePlus	COSMIC	5.604	Up-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q9Y570	PPME1	O14757	CHEK1	S15	P14L	14	Missense	proximal	-1	no	13.534	13.348	PhosphoSitePlus	COSMIC;CCLE	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q9Y570	PPME1	O14757	CHEK1	S15	L10I	10	Missense	distal	-5	no	13.534	11.503	PhosphoSitePlus	COSMIC	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q9Y570	PPME1	O14757	CHEK1	S42	P43L	43	Missense	proximal	1	no	9.468	9.496	EPSD	COSMIC;CCLE	5.604	Up-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	P27816	MAP4	O14757	CHEK1	S440	S439P	439	Missense	proximal	-1	no	5.241	5.688	EPSD	COSMIC	5.604	Gain
CAMK_CAMKL_CHK1_CHEK1_ST	P27816	MAP4	O14757	CHEK1	T451	D449Y	449	Missense	proximal	-2	no	9.226	9.291	EPSD	COSMIC	5.604	Up-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	P27816	MAP4	O14757	CHEK1	T451	T451A	451	Missense	central	0	yes	9.226	0.000	EPSD	COSMIC	5.604	Loss
CAMK_CAMKL_CHK1_CHEK1_ST	P27816	MAP4	O14757	CHEK1	T451	N457T	457	Missense	distal	6	no	9.226	9.402	EPSD	COSMIC	5.604	Up-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	P27816	MAP4	O14757	CHEK1	S602	S609Y	609	Missense	distal	7	no	8.609	8.095	EPSD	COSMIC	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	P27816	MAP4	O14757	CHEK1	S602	I601V	601	Missense	proximal	-1	no	8.609	8.747	EPSD	COSMIC	5.604	Up-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	P27816	MAP4	O14757	CHEK1	S742	G746S	746	Missense	distal	4	no	6.278	6.211	EPSD	COSMIC	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	P27816	MAP4	O14757	CHEK1	S742	L743F	743	Missense	proximal	1	no	6.278	6.282	EPSD	COSMIC;GDSC	5.604	Up-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	P27816	MAP4	O14757	CHEK1	S742	N737S	737	Missense	distal	-5	no	6.278	5.785	EPSD	COSMIC	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	P27816	MAP4	O14757	CHEK1	S801	Q805H	805	Missense	distal	4	no	6.145	6.306	EPSD	COSMIC	5.604	Up-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	P27816	MAP4	O14757	CHEK1	S915	R919W	919	Missense	distal	4	no	6.537	6.600	EPSD	COSMIC	5.604	Up-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	P27816	MAP4	O14757	CHEK1	T925	R919W	919	Missense	distal	-6	no	7.980	8.300	PhosphoSitePlus	COSMIC	5.604	Up-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	P27816	MAP4	O14757	CHEK1	S996	A989V	989	Missense	distal	-7	no	5.698	5.041	EPSD	COSMIC	5.604	Loss
CAMK_CAMKL_CHK1_CHEK1_ST	P27816	MAP4	O14757	CHEK1	S1041	I1045F	1045	Missense	distal	4	no	8.448	8.495	EPSD	COSMIC	5.604	Up-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	P27816	MAP4	O14757	CHEK1	S1073	A1067V	1067	Missense	distal	-6	no	7.338	7.476	EPSD	COSMIC	5.604	Up-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	P27816	MAP4	O14757	CHEK1	S1073	K1070N	1070	Missense	distal	-3	no	7.338	0.795	EPSD	COSMIC	5.604	Loss
CAMK_CAMKL_CHK1_CHEK1_ST	Q9UK53	ING1	O14757	CHEK1	S269	A272D	272	Missense	distal	3	no	4.676	6.140	EPSD	COSMIC	5.604	Gain
CAMK_CAMKL_CHK1_CHEK1_ST	Q9UK53	ING1	O14757	CHEK1	S342	A341V	341	Missense	proximal	-1	no	8.514	8.436	EPSD	COSMIC	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q9UK53	ING1	O14757	CHEK1	S342	P343T	343	Missense	proximal	1	no	8.514	8.558	EPSD	COSMIC	5.604	Up-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q9UK53	ING1	O14757	CHEK1	S342	D349N	349	Missense	distal	7	no	8.514	8.352	EPSD	COSMIC	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q9UK53	ING1	O14757	CHEK1	S342	E338D	338	Missense	distal	-4	no	8.514	8.373	EPSD	COSMIC	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	O43395	PRPF3	O14757	CHEK1	T280	A287V	287	Missense	distal	7	no	9.397	9.477	EPSD	COSMIC	5.604	Up-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	O43395	PRPF3	O14757	CHEK1	T280	R277H	277	Missense	distal	-3	no	9.397	3.588	EPSD	COSMIC;CCLE	5.604	Loss
CAMK_CAMKL_CHK1_CHEK1_ST	O43395	PRPF3	O14757	CHEK1	T280	R286C	286	Missense	distal	6	no	9.397	9.691	EPSD	COSMIC	5.604	Up-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	O43395	PRPF3	O14757	CHEK1	T280	R277C	277	Missense	distal	-3	no	9.397	1.306	EPSD	COSMIC	5.604	Loss
CAMK_CAMKL_CHK1_CHEK1_ST	O43395	PRPF3	O14757	CHEK1	T280	A287D	287	Missense	distal	7	no	9.397	9.739	EPSD	COSMIC	5.604	Up-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	O43395	PRPF3	O14757	CHEK1	T280	A283P	283	Missense	distal	3	no	9.397	9.633	EPSD	COSMIC	5.604	Up-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	O43395	PRPF3	O14757	CHEK1	S552	K557T	557	Missense	distal	5	no	7.654	7.411	EPSD	COSMIC	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	O43395	PRPF3	O14757	CHEK1	S552	N553D	553	Missense	proximal	1	no	7.654	7.761	EPSD	COSMIC	5.604	Up-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	O43395	PRPF3	O14757	CHEK1	S552	P554T	554	Missense	proximal	2	no	7.654	7.339	EPSD	COSMIC	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q00341	HDLBP	O14757	CHEK1	S126	Q123R	123	Missense	distal	-3	no	2.648	9.855	EPSD	COSMIC	5.604	Gain
CAMK_CAMKL_CHK1_CHEK1_ST	Q00341	HDLBP	O14757	CHEK1	T149	I143F	143	Missense	distal	-6	no	6.467	6.742	EPSD	COSMIC	5.604	Up-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q00341	HDLBP	O14757	CHEK1	T149	Q148H	148	Missense	proximal	-1	no	6.467	6.578	EPSD	COSMIC;GDSC;CCLE	5.604	Up-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q00341	HDLBP	O14757	CHEK1	T149	R146G	146	Missense	distal	-3	no	6.467	-1.307	EPSD	COSMIC	5.604	Loss
CAMK_CAMKL_CHK1_CHEK1_ST	Q00341	HDLBP	O14757	CHEK1	T149	A153V	153	Missense	distal	4	no	6.467	6.385	EPSD	COSMIC	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q00341	HDLBP	O14757	CHEK1	S611	I615M	615	Missense	distal	4	no	10.896	10.955	EPSD	COSMIC;GDSC;CCLE	5.604	Up-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q00341	HDLBP	O14757	CHEK1	S611	R608C	608	Missense	distal	-3	no	10.896	2.805	EPSD	COSMIC	5.604	Loss
CAMK_CAMKL_CHK1_CHEK1_ST	Q00341	HDLBP	O14757	CHEK1	S622	I615M	615	Missense	distal	-7	no	6.131	6.373	EPSD	COSMIC;GDSC;CCLE	5.604	Up-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q00341	HDLBP	O14757	CHEK1	S622	E620K	620	Missense	proximal	-2	no	6.131	5.988	EPSD	COSMIC	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q00341	HDLBP	O14757	CHEK1	S622	E625K	625	Missense	distal	3	no	6.131	5.315	EPSD	COSMIC	5.604	Loss
CAMK_CAMKL_CHK1_CHEK1_ST	Q00341	HDLBP	O14757	CHEK1	S645	A639V	639	Missense	distal	-6	no	13.038	13.176	EPSD	COSMIC	5.604	Up-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q00341	HDLBP	O14757	CHEK1	S645	I646F	646	Missense	proximal	1	no	13.038	13.069	EPSD	COSMIC	5.604	Up-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q00341	HDLBP	O14757	CHEK1	S645	S645Y	645	Missense	central	0	yes	13.038	0.000	EPSD	COSMIC	5.604	Loss
CAMK_CAMKL_CHK1_CHEK1_ST	Q00341	HDLBP	O14757	CHEK1	S667	L664R	664	Missense	distal	-3	no	-11.102	7.445	EPSD	COSMIC	5.604	Gain
CAMK_CAMKL_CHK1_CHEK1_ST	Q00341	HDLBP	O14757	CHEK1	S706	A712G	712	Missense	distal	6	no	10.384	10.207	EPSD	COSMIC	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q00341	HDLBP	O14757	CHEK1	S756	R751L	751	Missense	distal	-5	no	3.289	6.265	EPSD	COSMIC	5.604	Gain
CAMK_CAMKL_CHK1_CHEK1_ST	Q00341	HDLBP	O14757	CHEK1	T757	R760H	760	Missense	distal	3	no	9.881	9.912	EPSD	COSMIC	5.604	Up-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q00341	HDLBP	O14757	CHEK1	T757	R751L	751	Missense	distal	-6	no	9.881	9.986	EPSD	COSMIC	5.604	Up-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q00341	HDLBP	O14757	CHEK1	T842	D845N	845	Missense	distal	3	no	9.276	8.560	EPSD	COSMIC	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q00341	HDLBP	O14757	CHEK1	S1245	A1241T	1241	Missense	distal	-4	no	7.392	6.962	EPSD	COSMIC	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q86WR7	PROSER2	O14757	CHEK1	S27	R24P	24	Missense	distal	-3	no	7.358	0.221	EPSD	COSMIC	5.604	Loss
CAMK_CAMKL_CHK1_CHEK1_ST	Q86WR7	PROSER2	O14757	CHEK1	S31	R24P	24	Missense	distal	-7	no	5.817	5.407	EPSD	COSMIC	5.604	Loss
CAMK_CAMKL_CHK1_CHEK1_ST	Q86WR7	PROSER2	O14757	CHEK1	S38	S43R	43	Missense	distal	5	no	6.454	6.351	EPSD	COSMIC	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q86WR7	PROSER2	O14757	CHEK1	S43	S43R	43	Missense	central	0	yes	9.852	0.000	PhosphoSitePlus	COSMIC	5.604	Loss
CAMK_CAMKL_CHK1_CHEK1_ST	Q86WR7	PROSER2	O14757	CHEK1	T45	S43R	43	Missense	proximal	-2	no	10.315	10.414	EPSD	COSMIC	5.604	Up-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q86WR7	PROSER2	O14757	CHEK1	S179	R186K	186	Missense	distal	7	no	7.143	7.218	EPSD	COSMIC	5.604	Up-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q86WR7	PROSER2	O14757	CHEK1	S179	S179P	179	Missense	central	0	yes	7.143	0.000	EPSD	COSMIC	5.604	Loss
CAMK_CAMKL_CHK1_CHEK1_ST	Q86WR7	PROSER2	O14757	CHEK1	S179	P181L	181	Missense	proximal	2	no	7.143	6.826	EPSD	COSMIC	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q86WR7	PROSER2	O14757	CHEK1	S255	R252H	252	Missense	distal	-3	no	7.441	1.632	EPSD	COSMIC	5.604	Loss
CAMK_CAMKL_CHK1_CHEK1_ST	Q86WR7	PROSER2	O14757	CHEK1	S277	L271M	271	Missense	distal	-6	no	5.663	5.700	EPSD	COSMIC	5.604	Up-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q86WR7	PROSER2	O14757	CHEK1	S277	V278M	278	Missense	proximal	1	no	5.663	5.655	EPSD	COSMIC	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q86WR7	PROSER2	O14757	CHEK1	S400	A398T	398	Missense	proximal	-2	no	8.119	8.259	EPSD	COSMIC	5.604	Up-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q86WR7	PROSER2	O14757	CHEK1	S400	D399G	399	Missense	proximal	-1	no	8.119	8.168	EPSD	COSMIC	5.604	Up-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q86WR7	PROSER2	O14757	CHEK1	S400	P404T	404	Missense	distal	4	no	8.119	7.991	EPSD	COSMIC	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q86WR7	PROSER2	O14757	CHEK1	S400	Q393H	393	Missense	distal	-7	no	8.119	7.802	EPSD	COSMIC	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q86WR7	PROSER2	O14757	CHEK1	S435	L428V	428	Missense	distal	-7	no	8.060	8.738	EPSD	COSMIC;CCLE	5.604	Up-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q14004	CDK13	O14757	CHEK1	S16	G13R	13	Missense	distal	-3	no	2.743	10.518	EPSD	COSMIC	5.604	Gain
CAMK_CAMKL_CHK1_CHEK1_ST	Q14004	CDK13	O14757	CHEK1	S238	R234S	234	Missense	distal	-4	no	5.799	5.491	EPSD	COSMIC;CCLE	5.604	Loss
CAMK_CAMKL_CHK1_CHEK1_ST	Q14004	CDK13	O14757	CHEK1	S238	E241V	241	Missense	distal	3	no	5.799	4.678	EPSD	COSMIC	5.604	Loss
CAMK_CAMKL_CHK1_CHEK1_ST	Q14004	CDK13	O14757	CHEK1	S285	R280H	280	Missense	distal	-5	no	11.317	8.852	EPSD	COSMIC	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q14004	CDK13	O14757	CHEK1	S285	H279Y	279	Missense	distal	-6	no	11.317	11.449	EPSD	COSMIC	5.604	Up-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q14004	CDK13	O14757	CHEK1	S285	S286F	286	Missense	proximal	1	no	11.317	11.312	EPSD	COSMIC	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q14004	CDK13	O14757	CHEK1	S285	S285I	285	Missense	central	0	yes	11.317	0.000	EPSD	COSMIC	5.604	Loss
CAMK_CAMKL_CHK1_CHEK1_ST	Q14004	CDK13	O14757	CHEK1	S325	D323N	323	Missense	proximal	-2	no	8.291	8.433	EPSD	COSMIC;CCLE	5.604	Up-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q14004	CDK13	O14757	CHEK1	S342	R338L	338	Missense	distal	-4	no	5.769	5.513	EPSD	COSMIC	5.604	Loss
CAMK_CAMKL_CHK1_CHEK1_ST	Q14004	CDK13	O14757	CHEK1	S342	K339T	339	Missense	distal	-3	no	5.769	-10.974	EPSD	COSMIC	5.604	Loss
CAMK_CAMKL_CHK1_CHEK1_ST	Q14004	CDK13	O14757	CHEK1	S342	S340F	340	Missense	proximal	-2	no	5.769	6.059	EPSD	COSMIC;CCLE	5.604	Up-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q14004	CDK13	O14757	CHEK1	S360	R366H	366	Missense	distal	6	no	10.887	11.175	EPSD	COSMIC	5.604	Up-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q14004	CDK13	O14757	CHEK1	S369	S375T	375	Missense	distal	6	no	7.734	8.044	EPSD	COSMIC	5.604	Up-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q14004	CDK13	O14757	CHEK1	S369	Y376C	376	Missense	distal	7	no	7.734	7.935	EPSD	COSMIC	5.604	Up-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q14004	CDK13	O14757	CHEK1	S369	R366H	366	Missense	distal	-3	no	7.734	1.924	EPSD	COSMIC	5.604	Loss
CAMK_CAMKL_CHK1_CHEK1_ST	Q14004	CDK13	O14757	CHEK1	S369	S369G	369	Missense	central	0	yes	7.734	0.000	EPSD	COSMIC	5.604	Loss
CAMK_CAMKL_CHK1_CHEK1_ST	Q14004	CDK13	O14757	CHEK1	S369	R372H	372	Missense	distal	3	no	7.734	7.764	EPSD	COSMIC	5.604	Up-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q14004	CDK13	O14757	CHEK1	S369	R372C	372	Missense	distal	3	no	7.734	6.786	EPSD	COSMIC	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q14004	CDK13	O14757	CHEK1	S375	Y376C	376	Missense	proximal	1	no	8.517	8.551	EPSD	COSMIC	5.604	Up-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q14004	CDK13	O14757	CHEK1	S375	S369G	369	Missense	distal	-6	no	8.517	8.555	EPSD	COSMIC	5.604	Up-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q14004	CDK13	O14757	CHEK1	S375	G379D	379	Missense	distal	4	no	8.517	8.501	EPSD	COSMIC	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q14004	CDK13	O14757	CHEK1	S375	R372H	372	Missense	distal	-3	no	8.517	2.708	EPSD	COSMIC	5.604	Loss
CAMK_CAMKL_CHK1_CHEK1_ST	Q14004	CDK13	O14757	CHEK1	S375	R372C	372	Missense	distal	-3	no	8.517	0.426	EPSD	COSMIC	5.604	Loss
CAMK_CAMKL_CHK1_CHEK1_ST	Q14004	CDK13	O14757	CHEK1	S433	R427I	427	Missense	distal	-6	no	11.421	11.500	EPSD	COSMIC	5.604	Up-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q14004	CDK13	O14757	CHEK1	S433	S439F	439	Missense	distal	6	no	11.421	11.824	EPSD	COSMIC	5.604	Up-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q14004	CDK13	O14757	CHEK1	S437	S439F	439	Missense	proximal	2	no	10.637	10.492	PhosphoSitePlus	COSMIC	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q14004	CDK13	O14757	CHEK1	S863	R868W	868	Missense	distal	5	no	12.300	12.131	EPSD	COSMIC	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q14004	CDK13	O14757	CHEK1	S863	P869L	869	Missense	distal	6	no	12.300	12.090	EPSD	COSMIC;CCLE	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q14004	CDK13	O14757	CHEK1	T871	R868W	868	Missense	distal	-3	no	8.053	-25.550	EPSD	COSMIC	5.604	Loss
CAMK_CAMKL_CHK1_CHEK1_ST	Q14004	CDK13	O14757	CHEK1	T871	P869L	869	Missense	proximal	-2	no	8.053	7.874	EPSD	COSMIC;CCLE	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q14004	CDK13	O14757	CHEK1	T871	W878L	878	Missense	distal	7	no	8.053	8.454	EPSD	COSMIC	5.604	Up-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q14004	CDK13	O14757	CHEK1	T871	I875S	875	Missense	distal	4	no	8.053	8.002	EPSD	COSMIC	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q14004	CDK13	O14757	CHEK1	T1058	D1052N	1052	Missense	distal	-6	no	7.433	7.647	EPSD	COSMIC	5.604	Up-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q14004	CDK13	O14757	CHEK1	S1343	G1340R	1340	Missense	distal	-3	no	4.025	11.799	EPSD	COSMIC;GDSC;CCLE	5.604	Gain
CAMK_CAMKL_CHK1_CHEK1_ST	Q6T4R5	NHS	O14757	CHEK1	S140	R144S	144	Missense	distal	4	no	10.545	10.494	EPSD	COSMIC	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q6T4R5	NHS	O14757	CHEK1	S140	R144M	144	Missense	distal	4	no	10.545	10.605	EPSD	COSMIC	5.604	Up-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q6T4R5	NHS	O14757	CHEK1	S471	S477Y	477	Missense	distal	6	no	5.591	6.333	EPSD	COSMIC	5.604	Gain
CAMK_CAMKL_CHK1_CHEK1_ST	Q6T4R5	NHS	O14757	CHEK1	S471	S477F	477	Missense	distal	6	no	5.591	5.994	EPSD	COSMIC	5.604	Gain
CAMK_CAMKL_CHK1_CHEK1_ST	Q6T4R5	NHS	O14757	CHEK1	S566	L563Q	563	Missense	distal	-3	no	-4.378	6.962	EPSD	COSMIC	5.604	Gain
CAMK_CAMKL_CHK1_CHEK1_ST	Q6T4R5	NHS	O14757	CHEK1	S877	S884P	884	Missense	distal	7	no	5.841	5.896	EPSD	COSMIC	5.604	Up-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q6T4R5	NHS	O14757	CHEK1	S1062	P1066S	1066	Missense	distal	4	no	10.875	10.735	EPSD	COSMIC	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q6T4R5	NHS	O14757	CHEK1	S1062	S1067A	1067	Missense	distal	5	no	10.875	10.894	EPSD	COSMIC	5.604	Up-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q6T4R5	NHS	O14757	CHEK1	T1255	V1251L	1251	Missense	distal	-4	no	9.929	9.681	EPSD	COSMIC	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q6T4R5	NHS	O14757	CHEK1	S1461	G1462R	1462	Missense	proximal	1	no	13.096	13.105	EPSD	COSMIC	5.604	Up-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q6T4R5	NHS	O14757	CHEK1	S1461	G1462W	1462	Missense	proximal	1	no	13.096	13.075	EPSD	COSMIC	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q6T4R5	NHS	O14757	CHEK1	S1465	G1462R	1462	Missense	distal	-3	no	-2.158	5.617	EPSD	COSMIC	5.604	Gain
CAMK_CAMKL_CHK1_CHEK1_ST	Q5JTH9	RRP12	O14757	CHEK1	S23	I30V	30	Missense	distal	7	no	6.161	6.582	EPSD	COSMIC	5.604	Up-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q5JTH9	RRP12	O14757	CHEK1	S180	F187L	187	Missense	distal	7	no	10.028	10.450	EPSD	COSMIC;GDSC;CCLE	5.604	Up-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q5JTH9	RRP12	O14757	CHEK1	S180	P181S	181	Missense	proximal	1	no	10.028	10.065	EPSD	COSMIC	5.604	Up-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q5JTH9	RRP12	O14757	CHEK1	S180	V178I	178	Missense	proximal	-2	no	10.028	9.965	EPSD	COSMIC	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q5JTH9	RRP12	O14757	CHEK1	S180	P181H	181	Missense	proximal	1	no	10.028	10.025	EPSD	COSMIC	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q5JTH9	RRP12	O14757	CHEK1	S327	E320A	320	Missense	distal	-7	no	7.213	7.439	EPSD	COSMIC	5.604	Up-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q5JTH9	RRP12	O14757	CHEK1	S327	L330F	330	Missense	distal	3	no	7.213	7.835	EPSD	COSMIC	5.604	Up-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q5JTH9	RRP12	O14757	CHEK1	S652	R654H	654	Missense	proximal	2	no	7.770	7.789	EPSD	COSMIC	5.604	Up-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q5JTH9	RRP12	O14757	CHEK1	S737	L732I	732	Missense	distal	-5	no	8.407	6.375	EPSD	COSMIC	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q5JTH9	RRP12	O14757	CHEK1	S737	P743S	743	Missense	distal	6	no	8.407	7.787	EPSD	COSMIC	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q5JTH9	RRP12	O14757	CHEK1	S746	P743S	743	Missense	distal	-3	no	6.596	4.037	EPSD	COSMIC	5.604	Loss
CAMK_CAMKL_CHK1_CHEK1_ST	Q5JTH9	RRP12	O14757	CHEK1	S746	T749I	749	Missense	distal	3	no	6.596	6.365	EPSD	COSMIC	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q5JTH9	RRP12	O14757	CHEK1	S829	T828S	828	Missense	proximal	-1	no	6.515	6.310	EPSD	COSMIC	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q5JTH9	RRP12	O14757	CHEK1	S1049	E1055K	1055	Missense	distal	6	no	11.218	11.488	PhosphoSitePlus	COSMIC	5.604	Up-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q5JTH9	RRP12	O14757	CHEK1	S1105	A1101S	1101	Missense	distal	-4	no	10.895	10.516	EPSD	COSMIC	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q5JTH9	RRP12	O14757	CHEK1	S1105	A1107T	1107	Missense	proximal	2	no	10.895	10.047	EPSD	COSMIC;GDSC;CCLE	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q5JTH9	RRP12	O14757	CHEK1	S1105	R1102L	1102	Missense	distal	-3	no	10.895	-7.651	EPSD	COSMIC;GDSC;CCLE	5.604	Loss
CAMK_CAMKL_CHK1_CHEK1_ST	Q9HAW4	CLSPN	O14757	CHEK1	S341	S337F	337	Missense	distal	-4	no	5.730	5.488	EPSD	COSMIC	5.604	Loss
CAMK_CAMKL_CHK1_CHEK1_ST	Q9HAW4	CLSPN	O14757	CHEK1	S341	I347V	347	Missense	distal	6	no	5.730	5.964	EPSD	COSMIC	5.604	Up-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q9HAW4	CLSPN	O14757	CHEK1	S798	G804E	804	Missense	distal	6	no	7.299	6.817	EPSD	COSMIC	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q9HAW4	CLSPN	O14757	CHEK1	S798	R795C	795	Missense	distal	-3	no	7.299	-0.792	EPSD	COSMIC	5.604	Loss
CAMK_CAMKL_CHK1_CHEK1_ST	Q9HAW4	CLSPN	O14757	CHEK1	S798	F799C	799	Missense	proximal	1	no	7.299	7.320	EPSD	COSMIC	5.604	Up-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q9HAW4	CLSPN	O14757	CHEK1	S810	G804E	804	Missense	distal	-6	no	7.595	7.435	EPSD	COSMIC	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q9HAW4	CLSPN	O14757	CHEK1	S810	S808F	808	Missense	proximal	-2	no	7.595	7.885	EPSD	COSMIC	5.604	Up-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q9HAW4	CLSPN	O14757	CHEK1	S921	L927V	927	Missense	distal	6	no	9.563	9.430	EPSD	COSMIC	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q9HAW4	CLSPN	O14757	CHEK1	S921	T916I	916	Missense	distal	-5	no	9.563	9.588	EPSD	COSMIC	5.604	Up-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q9HAW4	CLSPN	O14757	CHEK1	S921	H926Y	926	Missense	distal	5	no	9.563	9.197	EPSD	COSMIC	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q9HAW4	CLSPN	O14757	CHEK1	S969	K966R	966	Missense	distal	-3	no	2.130	5.955	EPSD	COSMIC	5.604	Gain
CAMK_CAMKL_CHK1_CHEK1_ST	Q9HAW4	CLSPN	O14757	CHEK1	T1105	H1102R	1102	Missense	distal	-3	no	2.683	8.492	EPSD	COSMIC	5.604	Gain
CAMK_CAMKL_CHK1_CHEK1_ST	Q9HAW4	CLSPN	O14757	CHEK1	S1156	M1149I	1149	Missense	distal	-7	no	8.978	8.735	EPSD	COSMIC	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q9HAW4	CLSPN	O14757	CHEK1	S1156	D1155E	1155	Missense	proximal	-1	no	8.978	8.919	EPSD	COSMIC	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q9HAW4	CLSPN	O14757	CHEK1	S1223	E1230K	1230	Missense	distal	7	no	9.247	9.082	EPSD	COSMIC	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q9HAW4	CLSPN	O14757	CHEK1	S1223	R1224H	1224	Missense	proximal	1	no	9.247	9.182	EPSD	COSMIC	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q9HAW4	CLSPN	O14757	CHEK1	S1233	E1230K	1230	Missense	distal	-3	no	3.283	6.546	EPSD	COSMIC	5.604	Gain
CAMK_CAMKL_CHK1_CHEK1_ST	Q9HAW4	CLSPN	O14757	CHEK1	S1246	P1244S	1244	Missense	proximal	-2	no	7.155	6.871	EPSD	COSMIC	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q9HAW4	CLSPN	O14757	CHEK1	S1246	G1253S	1253	Missense	distal	7	no	7.155	7.057	EPSD	COSMIC	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q9HAW4	CLSPN	O14757	CHEK1	S1246	V1250A	1250	Missense	distal	4	no	7.155	7.238	EPSD	COSMIC	5.604	Up-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q9HAW4	CLSPN	O14757	CHEK1	S1300	A1295V	1295	Missense	distal	-5	no	6.030	8.470	EPSD	COSMIC	5.604	Up-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q9HAW4	CLSPN	O14757	CHEK1	S1300	E1298G	1298	Missense	proximal	-2	no	6.030	6.102	EPSD	COSMIC	5.604	Up-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q9HAW4	CLSPN	O14757	CHEK1	S1310	P1315L	1315	Missense	distal	5	no	8.199	8.037	EPSD	COSMIC	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q9HAW4	CLSPN	O14757	CHEK1	S1310	P1309R	1309	Missense	proximal	-1	no	8.199	7.914	EPSD	COSMIC	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q14738	PPP2R5D	O14757	CHEK1	S88	R91H	91	Missense	distal	3	no	8.975	9.006	EPSD	COSMIC	5.604	Up-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q14738	PPP2R5D	O14757	CHEK1	S88	Q87K	87	Missense	proximal	-1	no	8.975	8.811	EPSD	COSMIC	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q14738	PPP2R5D	O14757	CHEK1	S88	R86W	86	Missense	proximal	-2	no	8.975	9.097	EPSD	COSMIC	5.604	Up-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q14738	PPP2R5D	O14757	CHEK1	S88	S90Y	90	Missense	proximal	2	no	8.975	8.678	EPSD	COSMIC	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q14738	PPP2R5D	O14757	CHEK1	S89	R91H	91	Missense	proximal	2	no	7.439	7.458	EPSD	COSMIC	5.604	Up-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q14738	PPP2R5D	O14757	CHEK1	S89	Q87K	87	Missense	proximal	-2	no	7.439	7.212	EPSD	COSMIC	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q14738	PPP2R5D	O14757	CHEK1	S89	R86W	86	Missense	distal	-3	no	7.439	-26.164	EPSD	COSMIC	5.604	Loss
CAMK_CAMKL_CHK1_CHEK1_ST	Q14738	PPP2R5D	O14757	CHEK1	S89	S90Y	90	Missense	proximal	1	no	7.439	7.421	EPSD	COSMIC	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q14738	PPP2R5D	O14757	CHEK1	S90	Q87K	87	Missense	distal	-3	no	2.244	5.626	EPSD	COSMIC	5.604	Gain
CAMK_CAMKL_CHK1_CHEK1_ST	Q14738	PPP2R5D	O14757	CHEK1	S573	R570Q	570	Missense	distal	-3	no	13.785	6.578	EPSD	COSMIC	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q14738	PPP2R5D	O14757	CHEK1	S573	V579M	579	Missense	distal	6	no	13.785	13.910	EPSD	COSMIC	5.604	Up-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	P55039	DRG2	O14757	CHEK1	S72	T77K	77	Missense	distal	5	no	5.814	6.057	PhosphoSitePlus	COSMIC	5.604	Up-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	P55039	DRG2	O14757	CHEK1	S72	T77I	77	Missense	distal	5	no	5.814	5.893	PhosphoSitePlus	COSMIC	5.604	Up-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	P55039	DRG2	O14757	CHEK1	S72	G69V	69	Missense	distal	-3	no	5.814	5.125	PhosphoSitePlus	COSMIC	5.604	Loss
CAMK_CAMKL_CHK1_CHEK1_ST	O43660	PLRG1	O14757	CHEK1	S119	L126S	126	Missense	distal	7	no	12.179	12.186	PhosphoSitePlus	COSMIC	5.604	Up-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	O43660	PLRG1	O14757	CHEK1	T386	H381R	381	Missense	distal	-5	no	8.114	10.579	EPSD	COSMIC	5.604	Up-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	O43660	PLRG1	O14757	CHEK1	T386	P392Q	392	Missense	distal	6	no	8.114	7.575	EPSD	COSMIC	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	O43660	PLRG1	O14757	CHEK1	T386	G390C	390	Missense	distal	4	no	8.114	8.201	EPSD	COSMIC	5.604	Up-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	P15822	HIVEP1	O14757	CHEK1	S148	R144H	144	Missense	distal	-4	no	9.483	9.286	EPSD	COSMIC	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	P15822	HIVEP1	O14757	CHEK1	S523	A525V	525	Missense	proximal	2	no	7.735	7.172	EPSD	COSMIC;GDSC;CCLE	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	P15822	HIVEP1	O14757	CHEK1	S577	P583T	583	Missense	distal	6	no	9.026	8.718	EPSD	COSMIC	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	P15822	HIVEP1	O14757	CHEK1	S577	P578S	578	Missense	proximal	1	no	9.026	9.063	EPSD	COSMIC	5.604	Up-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	P15822	HIVEP1	O14757	CHEK1	S577	V570L	570	Missense	distal	-7	no	9.026	8.349	EPSD	COSMIC	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	P15822	HIVEP1	O14757	CHEK1	S681	P688S	688	Missense	distal	7	no	9.543	9.488	EPSD	COSMIC	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	P15822	HIVEP1	O14757	CHEK1	S698	Q701H	701	Missense	distal	3	no	7.030	5.999	EPSD	COSMIC	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	P15822	HIVEP1	O14757	CHEK1	S779	S785L	785	Missense	distal	6	no	10.293	10.703	EPSD	COSMIC	5.604	Up-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	P15822	HIVEP1	O14757	CHEK1	S779	S785P	785	Missense	distal	6	no	10.293	10.913	EPSD	COSMIC	5.604	Up-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	P15822	HIVEP1	O14757	CHEK1	S779	P783S	783	Missense	distal	4	no	10.293	10.153	EPSD	COSMIC	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	P15822	HIVEP1	O14757	CHEK1	S804	P810L	810	Missense	distal	6	no	10.048	9.838	EPSD	COSMIC;CCLE	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	P15822	HIVEP1	O14757	CHEK1	S804	S807F	807	Missense	distal	3	no	10.048	10.236	EPSD	COSMIC	5.604	Up-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	P15822	HIVEP1	O14757	CHEK1	S805	P810L	810	Missense	distal	5	no	9.547	9.385	EPSD	COSMIC;CCLE	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	P15822	HIVEP1	O14757	CHEK1	S805	S807F	807	Missense	proximal	2	no	9.547	9.403	EPSD	COSMIC	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	P15822	HIVEP1	O14757	CHEK1	S841	I836F	836	Missense	distal	-5	no	6.547	5.015	EPSD	COSMIC	5.604	Loss
CAMK_CAMKL_CHK1_CHEK1_ST	P15822	HIVEP1	O14757	CHEK1	S866	S864N	864	Missense	proximal	-2	no	7.550	7.739	EPSD	COSMIC	5.604	Up-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	P15822	HIVEP1	O14757	CHEK1	T1274	E1275Q	1275	Missense	proximal	1	no	5.923	5.857	EPSD	COSMIC	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	P15822	HIVEP1	O14757	CHEK1	S1368	I1371T	1371	Missense	distal	3	no	9.521	9.752	EPSD	COSMIC	5.604	Up-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	P15822	HIVEP1	O14757	CHEK1	S1387	F1388L	1388	Missense	proximal	1	no	6.320	6.316	EPSD	COSMIC	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	P15822	HIVEP1	O14757	CHEK1	S1387	K1386E	1386	Missense	proximal	-1	no	6.320	6.378	EPSD	COSMIC	5.604	Up-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	P15822	HIVEP1	O14757	CHEK1	S1434	N1436S	1436	Missense	proximal	2	no	11.920	11.738	EPSD	COSMIC	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	P15822	HIVEP1	O14757	CHEK1	S1434	G1427V	1427	Missense	distal	-7	no	11.920	11.935	EPSD	COSMIC	5.604	Up-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	P15822	HIVEP1	O14757	CHEK1	S1952	Q1950H	1950	Missense	proximal	-2	no	11.395	11.413	EPSD	COSMIC;CCLE	5.604	Up-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	P15822	HIVEP1	O14757	CHEK1	S1952	L1947F	1947	Missense	distal	-5	no	11.395	7.831	EPSD	COSMIC	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	P15822	HIVEP1	O14757	CHEK1	S2101	R2096H	2096	Missense	distal	-5	no	5.982	3.517	EPSD	COSMIC;CCLE	5.604	Loss
CAMK_CAMKL_CHK1_CHEK1_ST	P15822	HIVEP1	O14757	CHEK1	S2101	G2094V	2094	Missense	distal	-7	no	5.982	5.997	EPSD	COSMIC	5.604	Up-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	P15822	HIVEP1	O14757	CHEK1	T2109	T2111A	2111	Missense	proximal	2	no	5.024	5.872	EPSD	COSMIC	5.604	Gain
CAMK_CAMKL_CHK1_CHEK1_ST	P15822	HIVEP1	O14757	CHEK1	S2273	A2277V	2277	Missense	distal	4	no	7.067	6.985	EPSD	COSMIC	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	P15822	HIVEP1	O14757	CHEK1	S2599	N2592S	2592	Missense	distal	-7	no	8.799	9.336	EPSD	COSMIC	5.604	Up-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	P15822	HIVEP1	O14757	CHEK1	S2599	P2604L	2604	Missense	distal	5	no	8.799	8.637	EPSD	COSMIC	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	P15822	HIVEP1	O14757	CHEK1	S2669	S2669F	2669	Missense	central	0	yes	9.447	0.000	EPSD	COSMIC	5.604	Loss
CAMK_CAMKL_CHK1_CHEK1_ST	P15822	HIVEP1	O14757	CHEK1	T2699	V2705M	2705	Missense	distal	6	no	6.307	6.432	EPSD	COSMIC	5.604	Up-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	P15822	HIVEP1	O14757	CHEK1	T2699	D2704Y	2704	Missense	distal	5	no	6.307	5.766	EPSD	COSMIC	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	P15822	HIVEP1	O14757	CHEK1	T2699	S2706G	2706	Missense	distal	7	no	6.307	6.406	EPSD	COSMIC	5.604	Up-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	P15822	HIVEP1	O14757	CHEK1	T2699	R2695M	2695	Missense	distal	-4	no	6.307	6.144	EPSD	COSMIC	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q53F19	NCBP3	O14757	CHEK1	S73	E68K	68	Missense	distal	-5	no	3.770	6.332	EPSD	COSMIC	5.604	Gain
CAMK_CAMKL_CHK1_CHEK1_ST	Q53F19	NCBP3	O14757	CHEK1	S100	H97R	97	Missense	distal	-3	no	5.301	11.110	PhosphoSitePlus	COSMIC	5.604	Gain
CAMK_CAMKL_CHK1_CHEK1_ST	Q53F19	NCBP3	O14757	CHEK1	S193	E194K	194	Missense	proximal	1	no	11.703	11.629	EPSD	COSMIC	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q53F19	NCBP3	O14757	CHEK1	S387	R386W	386	Missense	proximal	-1	no	7.910	8.027	EPSD	COSMIC	5.604	Up-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q53F19	NCBP3	O14757	CHEK1	S387	S387R	387	Missense	central	0	yes	7.910	0.000	EPSD	COSMIC	5.604	Loss
CAMK_CAMKL_CHK1_CHEK1_ST	Q53F19	NCBP3	O14757	CHEK1	S387	L380V	380	Missense	distal	-7	no	7.910	8.588	EPSD	COSMIC	5.604	Up-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q53F19	NCBP3	O14757	CHEK1	S387	R391Q	391	Missense	distal	4	no	7.910	7.909	EPSD	COSMIC	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q53F19	NCBP3	O14757	CHEK1	S387	S389C	389	Missense	proximal	2	no	7.910	7.549	EPSD	COSMIC	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q53F19	NCBP3	O14757	CHEK1	S387	R386Q	386	Missense	proximal	-1	no	7.910	7.925	EPSD	COSMIC;GDSC	5.604	Up-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q53F19	NCBP3	O14757	CHEK1	S389	R386W	386	Missense	distal	-3	no	7.654	-25.949	EPSD	COSMIC	5.604	Loss
CAMK_CAMKL_CHK1_CHEK1_ST	Q53F19	NCBP3	O14757	CHEK1	S389	S387R	387	Missense	proximal	-2	no	7.654	7.753	EPSD	COSMIC	5.604	Up-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q53F19	NCBP3	O14757	CHEK1	S389	R391Q	391	Missense	proximal	2	no	7.654	8.183	EPSD	COSMIC	5.604	Up-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q53F19	NCBP3	O14757	CHEK1	S389	S389C	389	Missense	central	0	yes	7.654	0.000	EPSD	COSMIC	5.604	Loss
CAMK_CAMKL_CHK1_CHEK1_ST	Q53F19	NCBP3	O14757	CHEK1	S389	R386Q	386	Missense	distal	-3	no	7.654	0.447	EPSD	COSMIC;GDSC	5.604	Loss
CAMK_CAMKL_CHK1_CHEK1_ST	Q53F19	NCBP3	O14757	CHEK1	S412	T413M	413	Missense	proximal	1	no	5.794	5.773	EPSD	COSMIC	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q53F19	NCBP3	O14757	CHEK1	S412	M410I	410	Missense	proximal	-2	no	5.794	5.780	EPSD	COSMIC;GDSC	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q53F19	NCBP3	O14757	CHEK1	S412	E407Q	407	Missense	distal	-5	no	5.794	6.784	EPSD	COSMIC	5.604	Up-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q53F19	NCBP3	O14757	CHEK1	S412	S419R	419	Missense	distal	7	no	5.794	5.887	EPSD	COSMIC	5.604	Up-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q53F19	NCBP3	O14757	CHEK1	S444	D443N	443	Missense	proximal	-1	no	9.003	9.092	EPSD	COSMIC	5.604	Up-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q53F19	NCBP3	O14757	CHEK1	S444	R441M	441	Missense	distal	-3	no	9.003	3.855	EPSD	COSMIC	5.604	Loss
CAMK_CAMKL_CHK1_CHEK1_ST	Q53F19	NCBP3	O14757	CHEK1	S500	R497I	497	Missense	distal	-3	no	10.886	2.128	EPSD	COSMIC;GDSC	5.604	Loss
CAMK_CAMKL_CHK1_CHEK1_ST	Q53F19	NCBP3	O14757	CHEK1	S500	P501S	501	Missense	proximal	1	no	10.886	10.923	EPSD	COSMIC	5.604	Up-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q53F19	NCBP3	O14757	CHEK1	S500	P501L	501	Missense	proximal	1	no	10.886	10.914	EPSD	COSMIC	5.604	Up-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q53F19	NCBP3	O14757	CHEK1	S506	P501S	501	Missense	distal	-5	no	4.156	5.675	EPSD	COSMIC	5.604	Gain
CAMK_CAMKL_CHK1_CHEK1_ST	Q53F19	NCBP3	O14757	CHEK1	S506	P501L	501	Missense	distal	-5	no	4.156	8.863	EPSD	COSMIC	5.604	Gain
CAMK_CAMKL_CHK1_CHEK1_ST	Q53F19	NCBP3	O14757	CHEK1	S516	V511I	511	Missense	distal	-5	no	10.489	11.935	EPSD	COSMIC;GDSC	5.604	Up-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q53F19	NCBP3	O14757	CHEK1	S516	V510F	510	Missense	distal	-6	no	10.489	10.751	EPSD	COSMIC;GDSC	5.604	Up-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q53F19	NCBP3	O14757	CHEK1	S516	P509L	509	Missense	distal	-7	no	10.489	10.275	EPSD	COSMIC	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q53F19	NCBP3	O14757	CHEK1	S516	S516F	516	Missense	central	0	yes	10.489	0.000	EPSD	COSMIC	5.604	Loss
CAMK_CAMKL_CHK1_CHEK1_ST	Q53F19	NCBP3	O14757	CHEK1	S516	S521G	521	Missense	distal	5	no	10.489	10.298	EPSD	COSMIC	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q53F19	NCBP3	O14757	CHEK1	S516	L523P	523	Missense	distal	7	no	10.489	10.552	EPSD	COSMIC	5.604	Up-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q53F19	NCBP3	O14757	CHEK1	S530	P526S	526	Missense	distal	-4	no	5.879	5.643	EPSD	COSMIC	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q53F19	NCBP3	O14757	CHEK1	S530	Q528R	528	Missense	proximal	-2	no	5.879	5.833	EPSD	COSMIC	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q53F19	NCBP3	O14757	CHEK1	S530	A535T	535	Missense	distal	5	no	5.879	5.638	EPSD	COSMIC;GDSC	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q53F19	NCBP3	O14757	CHEK1	S530	S530C	530	Missense	central	0	yes	5.879	0.000	EPSD	COSMIC	5.604	Loss
CAMK_CAMKL_CHK1_CHEK1_ST	Q53F19	NCBP3	O14757	CHEK1	S530	L523P	523	Missense	distal	-7	no	5.879	6.094	EPSD	COSMIC	5.604	Up-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q53F19	NCBP3	O14757	CHEK1	S613	E619K	619	Missense	distal	6	no	5.434	5.704	EPSD	COSMIC	5.604	Gain
CAMK_CAMKL_CHK1_CHEK1_ST	Q53F19	NCBP3	O14757	CHEK1	S613	I606V	606	Missense	distal	-7	no	5.434	5.870	EPSD	COSMIC	5.604	Gain
CAMK_CAMKL_CHK1_CHEK1_ST	Q9HB96	FANCE	O14757	CHEK1	S374	S380F	380	Missense	distal	6	no	14.596	14.999	EPSD;PhosphoSitePlus	COSMIC	5.604	Up-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q9HB96	FANCE	O14757	CHEK1	S486	Y489F	489	Missense	distal	3	no	4.840	6.257	EPSD	COSMIC	5.604	Gain
CAMK_CAMKL_CHK1_CHEK1_ST	Q96QD9	FYTTD1	O14757	CHEK1	T6	R7Q	7	Missense	proximal	1	no	7.471	7.479	EPSD	COSMIC	5.604	Up-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q96QD9	FYTTD1	O14757	CHEK1	S118	L125V	125	Missense	distal	7	no	7.159	7.296	EPSD	COSMIC	5.604	Up-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q96QD9	FYTTD1	O14757	CHEK1	S118	R122H	122	Missense	distal	4	no	7.159	7.320	EPSD	COSMIC	5.604	Up-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	P06493	CDK1	O14757	CHEK1	T25	V18L	18	Missense	distal	-7	no	10.871	10.193	EPSD	COSMIC	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	P06493	CDK1	O14757	CHEK1	T25	V30E	30	Missense	distal	5	no	10.871	11.041	EPSD	COSMIC	5.604	Up-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	P06493	CDK1	O14757	CHEK1	S53	S53C	53	Missense	central	0	yes	5.802	0.000	EPSD	COSMIC	5.604	Loss
CAMK_CAMKL_CHK1_CHEK1_ST	P06493	CDK1	O14757	CHEK1	T183	G177R	177	Missense	distal	-6	no	7.979	7.862	EPSD	COSMIC;GDSC;CCLE	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	P06493	CDK1	O14757	CHEK1	S208	S208L	208	Missense	central	0	yes	9.309	0.000	PhosphoSitePlus	COSMIC	5.604	Loss
CAMK_CAMKL_CHK1_CHEK1_ST	P06493	CDK1	O14757	CHEK1	S208	P202L	202	Missense	distal	-6	no	9.309	9.236	PhosphoSitePlus	COSMIC	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q9BY77	POLDIP3	O14757	CHEK1	S127	A129V	129	Missense	proximal	2	no	7.112	6.549	EPSD	COSMIC;CCLE	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q9BY77	POLDIP3	O14757	CHEK1	T256	R255W	255	Missense	proximal	-1	no	7.393	7.510	EPSD	COSMIC	5.604	Up-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q9BY77	POLDIP3	O14757	CHEK1	T256	M253V	253	Missense	distal	-3	no	7.393	4.078	EPSD	COSMIC	5.604	Loss
CAMK_CAMKL_CHK1_CHEK1_ST	Q9BY77	POLDIP3	O14757	CHEK1	T256	T256A	256	Missense	central	0	yes	7.393	0.000	EPSD	COSMIC;GDSC;CCLE	5.604	Loss
CAMK_CAMKL_CHK1_CHEK1_ST	Q9BY77	POLDIP3	O14757	CHEK1	S375	R379H	379	Missense	distal	4	no	6.093	6.254	EPSD	COSMIC	5.604	Up-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q9BY77	POLDIP3	O14757	CHEK1	S375	E374K	374	Missense	proximal	-1	no	6.093	6.035	EPSD	COSMIC	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q9BY77	POLDIP3	O14757	CHEK1	S383	P390H	390	Missense	distal	7	no	9.236	8.980	EPSD	COSMIC	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q9BY77	POLDIP3	O14757	CHEK1	S383	R379H	379	Missense	distal	-4	no	9.236	9.038	EPSD	COSMIC	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q9BY77	POLDIP3	O14757	CHEK1	S383	S383Y	383	Missense	central	0	yes	9.236	0.000	EPSD	COSMIC	5.604	Loss
CAMK_CAMKL_CHK1_CHEK1_ST	Q9BY77	POLDIP3	O14757	CHEK1	S383	A384S	384	Missense	proximal	1	no	9.236	9.218	EPSD	COSMIC;GDSC;CCLE	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	P26373	RPL13	O14757	CHEK1	S77	V70A	70	Missense	distal	-7	no	9.940	10.596	EPSD	COSMIC	5.604	Up-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	P26373	RPL13	O14757	CHEK1	S77	A84G	84	Missense	distal	7	no	9.940	9.989	EPSD	COSMIC	5.604	Up-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	P26373	RPL13	O14757	CHEK1	S77	E80K	80	Missense	distal	3	no	9.940	9.124	EPSD	COSMIC	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	P26373	RPL13	O14757	CHEK1	S106	A112T	112	Missense	distal	6	no	8.211	8.134	EPSD	COSMIC	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	P26373	RPL13	O14757	CHEK1	S132	S139N	139	Missense	distal	7	no	7.319	7.548	EPSD	COSMIC	5.604	Up-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	P26373	RPL13	O14757	CHEK1	S132	K135N	135	Missense	distal	3	no	7.319	7.516	EPSD	COSMIC	5.604	Up-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	P26373	RPL13	O14757	CHEK1	S132	P128L	128	Missense	distal	-4	no	7.319	7.135	EPSD	COSMIC	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	P26373	RPL13	O14757	CHEK1	S139	S140Y	140	Missense	proximal	1	no	6.106	6.089	EPSD	COSMIC	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	P26373	RPL13	O14757	CHEK1	S139	S139N	139	Missense	central	0	yes	6.106	0.000	EPSD	COSMIC	5.604	Loss
CAMK_CAMKL_CHK1_CHEK1_ST	P26373	RPL13	O14757	CHEK1	S139	K135N	135	Missense	distal	-4	no	6.106	5.992	EPSD	COSMIC	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	P26373	RPL13	O14757	CHEK1	S140	S140Y	140	Missense	central	0	yes	6.494	0.000	EPSD	COSMIC	5.604	Loss
CAMK_CAMKL_CHK1_CHEK1_ST	P26373	RPL13	O14757	CHEK1	S140	S139N	139	Missense	proximal	-1	no	6.494	6.713	EPSD	COSMIC	5.604	Up-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	P26373	RPL13	O14757	CHEK1	S140	K135N	135	Missense	distal	-5	no	6.494	5.601	EPSD	COSMIC	5.604	Loss
CAMK_CAMKL_CHK1_CHEK1_ST	P26373	RPL13	O14757	CHEK1	T170	R167L	167	Missense	distal	-3	no	14.182	-4.365	PhosphoSitePlus	COSMIC;CCLE	5.604	Loss
CAMK_CAMKL_CHK1_CHEK1_ST	P26373	RPL13	O14757	CHEK1	T170	N175S	175	Missense	distal	5	no	14.182	14.184	PhosphoSitePlus	COSMIC	5.604	Up-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	P18858	LIG1	O14757	CHEK1	T97	P95H	95	Missense	proximal	-2	no	6.890	6.770	EPSD	COSMIC	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	P18858	LIG1	O14757	CHEK1	T97	N102H	102	Missense	distal	5	no	6.890	6.804	EPSD	COSMIC	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	P18858	LIG1	O14757	CHEK1	T311	R305G	305	Missense	distal	-6	no	7.858	7.976	EPSD	COSMIC	5.604	Up-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	P18858	LIG1	O14757	CHEK1	T311	N314K	314	Missense	distal	3	no	7.858	7.661	EPSD	COSMIC	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	P18858	LIG1	O14757	CHEK1	T311	T311K	311	Missense	central	0	yes	7.858	0.000	EPSD	COSMIC	5.604	Loss
CAMK_CAMKL_CHK1_CHEK1_ST	P18858	LIG1	O14757	CHEK1	T311	L315F	315	Missense	distal	4	no	7.858	7.920	EPSD	COSMIC	5.604	Up-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	P18858	LIG1	O14757	CHEK1	T311	S318I	318	Missense	distal	7	no	7.858	7.566	EPSD	COSMIC	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	P18858	LIG1	O14757	CHEK1	S419	S419P	419	Missense	central	0	yes	7.217	0.000	EPSD	COSMIC	5.604	Loss
CAMK_CAMKL_CHK1_CHEK1_ST	P18858	LIG1	O14757	CHEK1	S419	S417R	417	Missense	proximal	-2	no	7.217	7.316	EPSD	COSMIC	5.604	Up-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	P18858	LIG1	O14757	CHEK1	S419	A418T	418	Missense	proximal	-1	no	7.217	7.089	EPSD	COSMIC	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	P18858	LIG1	O14757	CHEK1	T420	S417R	417	Missense	distal	-3	no	0.169	9.865	EPSD	COSMIC	5.604	Gain
CAMK_CAMKL_CHK1_CHEK1_ST	P18858	LIG1	O14757	CHEK1	S447	G448R	448	Missense	proximal	1	no	8.545	8.554	EPSD	COSMIC	5.604	Up-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	P18858	LIG1	O14757	CHEK1	S447	R449W	449	Missense	proximal	2	no	8.545	8.370	EPSD	COSMIC	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	P18858	LIG1	O14757	CHEK1	S447	R451H	451	Missense	distal	4	no	8.545	8.706	EPSD	COSMIC	5.604	Up-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	P18858	LIG1	O14757	CHEK1	S447	F441L	441	Missense	distal	-6	no	8.545	8.296	EPSD	COSMIC	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	P18858	LIG1	O14757	CHEK1	S552	G550S	550	Missense	proximal	-2	no	7.927	7.794	EPSD	COSMIC	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	P18858	LIG1	O14757	CHEK1	S552	R549L	549	Missense	distal	-3	no	7.927	-10.620	EPSD	COSMIC	5.604	Loss
CAMK_CAMKL_CHK1_CHEK1_ST	P18858	LIG1	O14757	CHEK1	T889	P884L	884	Missense	distal	-5	no	4.106	8.813	EPSD	COSMIC;CCLE	5.604	Gain
CAMK_CAMKL_CHK1_CHEK1_ST	P18858	LIG1	O14757	CHEK1	S901	N905K	905	Missense	distal	4	no	14.400	14.332	EPSD	COSMIC	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	P43405	SYK	O14757	CHEK1	S93	S96F	96	Missense	distal	3	no	7.128	7.316	EPSD	COSMIC	5.604	Up-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	P43405	SYK	O14757	CHEK1	S93	S93F	93	Missense	central	0	yes	7.128	0.000	EPSD	COSMIC	5.604	Loss
CAMK_CAMKL_CHK1_CHEK1_ST	P43405	SYK	O14757	CHEK1	S93	H92Y	92	Missense	proximal	-1	no	7.128	7.170	EPSD	COSMIC	5.604	Up-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	P43405	SYK	O14757	CHEK1	S93	D87Y	87	Missense	distal	-6	no	7.128	7.462	EPSD	COSMIC	5.604	Up-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	P43405	SYK	O14757	CHEK1	S93	V100F	100	Missense	distal	7	no	7.128	6.569	EPSD	COSMIC	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	P43405	SYK	O14757	CHEK1	S93	Q94R	94	Missense	proximal	1	no	7.128	7.119	EPSD	COSMIC	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	P43405	SYK	O14757	CHEK1	S178	E177K	177	Missense	proximal	-1	no	8.923	8.865	EPSD	COSMIC	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	P43405	SYK	O14757	CHEK1	T256	K261R	261	Missense	distal	5	no	8.766	8.643	EPSD	COSMIC	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	P43405	SYK	O14757	CHEK1	S295	S297F	297	Missense	proximal	2	no	11.476	11.332	PhosphoSitePlus	COSMIC	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	P43405	SYK	O14757	CHEK1	S295	I293L	293	Missense	proximal	-2	no	11.476	11.453	PhosphoSitePlus	COSMIC	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	P43405	SYK	O14757	CHEK1	S295	S291P	291	Missense	distal	-4	no	11.476	11.713	PhosphoSitePlus	COSMIC	5.604	Up-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	P43405	SYK	O14757	CHEK1	S297	S297F	297	Missense	central	0	yes	5.822	0.000	EPSD	COSMIC	5.604	Loss
CAMK_CAMKL_CHK1_CHEK1_ST	P43405	SYK	O14757	CHEK1	S297	I293L	293	Missense	distal	-4	no	5.822	5.854	EPSD	COSMIC	5.604	Up-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	P43405	SYK	O14757	CHEK1	S297	R304I	304	Missense	distal	7	no	5.822	5.437	EPSD	COSMIC	5.604	Loss
CAMK_CAMKL_CHK1_CHEK1_ST	P43405	SYK	O14757	CHEK1	S297	S291P	291	Missense	distal	-6	no	5.822	5.919	EPSD	COSMIC	5.604	Up-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	P43405	SYK	O14757	CHEK1	S307	A309S	309	Missense	proximal	2	no	12.325	11.869	EPSD	COSMIC	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	P43405	SYK	O14757	CHEK1	S307	A309E	309	Missense	proximal	2	no	12.325	12.418	EPSD	COSMIC	5.604	Up-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	P43405	SYK	O14757	CHEK1	S307	G311E	311	Missense	distal	4	no	12.325	12.216	EPSD	COSMIC	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	P43405	SYK	O14757	CHEK1	S307	S306F	306	Missense	proximal	-1	no	12.325	12.599	EPSD	COSMIC	5.604	Up-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	P43405	SYK	O14757	CHEK1	S307	P308T	308	Missense	proximal	1	no	12.325	12.369	EPSD	COSMIC	5.604	Up-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	P43405	SYK	O14757	CHEK1	S307	S307F	307	Missense	central	0	yes	12.325	0.000	EPSD	COSMIC	5.604	Loss
CAMK_CAMKL_CHK1_CHEK1_ST	P43405	SYK	O14757	CHEK1	S307	R313W	313	Missense	distal	6	no	12.325	12.791	EPSD	COSMIC	5.604	Up-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	P43405	SYK	O14757	CHEK1	S307	R304I	304	Missense	distal	-3	no	12.325	3.567	EPSD	COSMIC	5.604	Loss
CAMK_CAMKL_CHK1_CHEK1_ST	P43405	SYK	O14757	CHEK1	S307	Q310L	310	Missense	distal	3	no	12.325	10.831	EPSD	COSMIC	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	P43405	SYK	O14757	CHEK1	S307	P308H	308	Missense	proximal	1	no	12.325	12.322	EPSD	COSMIC	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	P43405	SYK	O14757	CHEK1	S307	R313L	313	Missense	distal	6	no	12.325	12.647	EPSD	COSMIC	5.604	Up-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	P43405	SYK	O14757	CHEK1	S316	A309S	309	Missense	distal	-7	no	8.686	8.236	EPSD	COSMIC	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	P43405	SYK	O14757	CHEK1	S316	A309E	309	Missense	distal	-7	no	8.686	8.459	EPSD	COSMIC	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	P43405	SYK	O14757	CHEK1	S316	G311E	311	Missense	distal	-5	no	8.686	7.465	EPSD	COSMIC	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	P43405	SYK	O14757	CHEK1	S316	P322S	322	Missense	distal	6	no	8.686	8.066	EPSD	COSMIC	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	P43405	SYK	O14757	CHEK1	S316	R313W	313	Missense	distal	-3	no	8.686	-24.917	EPSD	COSMIC	5.604	Loss
CAMK_CAMKL_CHK1_CHEK1_ST	P43405	SYK	O14757	CHEK1	S316	Q310L	310	Missense	distal	-6	no	8.686	8.708	EPSD	COSMIC	5.604	Up-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	P43405	SYK	O14757	CHEK1	S316	P322L	322	Missense	distal	6	no	8.686	8.476	EPSD	COSMIC	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	P43405	SYK	O14757	CHEK1	S316	R313L	313	Missense	distal	-3	no	8.686	-9.861	EPSD	COSMIC	5.604	Loss
CAMK_CAMKL_CHK1_CHEK1_ST	P43405	SYK	O14757	CHEK1	S316	S316N	316	Missense	central	0	yes	8.686	0.000	EPSD	COSMIC	5.604	Loss
CAMK_CAMKL_CHK1_CHEK1_ST	P43405	SYK	O14757	CHEK1	S316	S316C	316	Missense	central	0	yes	8.686	0.000	EPSD	COSMIC	5.604	Loss
CAMK_CAMKL_CHK1_CHEK1_ST	P43405	SYK	O14757	CHEK1	S579	T582A	582	Missense	distal	3	no	5.736	5.973	EPSD	COSMIC	5.604	Up-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	P43405	SYK	O14757	CHEK1	S579	A583T	583	Missense	distal	4	no	5.736	5.554	EPSD	COSMIC	5.604	Loss
CAMK_CAMKL_CHK1_CHEK1_ST	P43405	SYK	O14757	CHEK1	S579	M584I	584	Missense	distal	5	no	5.736	5.705	EPSD	COSMIC	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	P52294	KPNA1	O14757	CHEK1	S244	S244I	244	Missense	central	0	yes	13.709	0.000	EPSD	COSMIC	5.604	Loss
CAMK_CAMKL_CHK1_CHEK1_ST	Q8N4C8	MINK1	O14757	CHEK1	T187	P192L	192	Missense	distal	5	no	8.698	8.536	EPSD	COSMIC	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q8N4C8	MINK1	O14757	CHEK1	T187	P192S	192	Missense	distal	5	no	8.698	8.780	EPSD	COSMIC	5.604	Up-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q8N4C8	MINK1	O14757	CHEK1	T187	V182A	182	Missense	distal	-5	no	8.698	6.258	EPSD	COSMIC	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q8N4C8	MINK1	O14757	CHEK1	S674	Q670H	670	Missense	distal	-4	no	10.421	10.064	EPSD	COSMIC	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q8N4C8	MINK1	O14757	CHEK1	S674	T681N	681	Missense	distal	7	no	10.421	10.717	EPSD	COSMIC	5.604	Up-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q8N4C8	MINK1	O14757	CHEK1	S699	S701F	701	Missense	proximal	2	no	9.766	9.621	EPSD	COSMIC	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q8N4C8	MINK1	O14757	CHEK1	S701	S701F	701	Missense	central	0	yes	9.668	0.000	EPSD	COSMIC	5.604	Loss
CAMK_CAMKL_CHK1_CHEK1_ST	Q8N4C8	MINK1	O14757	CHEK1	S749	P742L	742	Missense	distal	-7	no	8.314	8.100	EPSD	COSMIC	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q8N4C8	MINK1	O14757	CHEK1	S749	R746C	746	Missense	distal	-3	no	8.314	0.222	EPSD	COSMIC	5.604	Loss
CAMK_CAMKL_CHK1_CHEK1_ST	Q8N4C8	MINK1	O14757	CHEK1	S749	L751F	751	Missense	proximal	2	no	8.314	8.564	EPSD	COSMIC	5.604	Up-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q8N4C8	MINK1	O14757	CHEK1	S749	E745D	745	Missense	distal	-4	no	8.314	8.173	EPSD	COSMIC	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q8N4C8	MINK1	O14757	CHEK1	S993	P999H	999	Missense	distal	6	no	10.038	9.794	EPSD	COSMIC	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q8N4C8	MINK1	O14757	CHEK1	S1006	E1010V	1010	Missense	distal	4	no	11.868	12.020	EPSD	COSMIC	5.604	Up-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q8N4C8	MINK1	O14757	CHEK1	S1006	P999H	999	Missense	distal	-7	no	11.868	12.219	EPSD	COSMIC	5.604	Up-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	P30307	CDC25C	O14757	CHEK1	S147	K140N	140	Missense	distal	-7	no	7.791	6.333	EPSD	COSMIC	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	P30307	CDC25C	O14757	CHEK1	S147	D154N	154	Missense	distal	7	no	7.791	7.629	EPSD	COSMIC	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	P30307	CDC25C	O14757	CHEK1	S216	S216L	216	Missense	central	0	yes	12.705	0.000	PhosphoSitePlus	COSMIC	5.604	Loss
CAMK_CAMKL_CHK1_CHEK1_ST	P30307	CDC25C	O14757	CHEK1	S216	G210R	210	Missense	distal	-6	no	12.705	12.587	PhosphoSitePlus	COSMIC	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	P30307	CDC25C	O14757	CHEK1	S247	S247F	247	Missense	central	0	yes	8.170	0.000	EPSD	COSMIC	5.604	Loss
CAMK_CAMKL_CHK1_CHEK1_ST	P30307	CDC25C	O14757	CHEK1	S247	Y245S	245	Missense	proximal	-2	no	8.170	8.057	EPSD	COSMIC	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	P30307	CDC25C	O14757	CHEK1	S247	K244T	244	Missense	distal	-3	no	8.170	-8.574	EPSD	COSMIC	5.604	Loss
CAMK_CAMKL_CHK1_CHEK1_ST	P30307	CDC25C	O14757	CHEK1	S247	G250E	250	Missense	distal	3	no	8.170	9.717	EPSD	COSMIC	5.604	Up-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	P30307	CDC25C	O14757	CHEK1	S247	G250W	250	Missense	distal	3	no	8.170	8.117	EPSD	COSMIC	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	P30307	CDC25C	O14757	CHEK1	S247	S247C	247	Missense	central	0	yes	8.170	0.000	EPSD	COSMIC	5.604	Loss
CAMK_CAMKL_CHK1_CHEK1_ST	P30307	CDC25C	O14757	CHEK1	S263	D266H	266	Missense	distal	3	no	10.181	8.651	EPSD	COSMIC	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	P30307	CDC25C	O14757	CHEK1	S263	L264R	264	Missense	proximal	1	no	10.181	10.216	EPSD	COSMIC	5.604	Up-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	P30307	CDC25C	O14757	CHEK1	S449	R448Q	448	Missense	proximal	-1	no	9.931	9.947	EPSD	COSMIC	5.604	Up-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	P30307	CDC25C	O14757	CHEK1	S449	E443K	443	Missense	distal	-6	no	9.931	9.963	EPSD	COSMIC	5.604	Up-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	P30307	CDC25C	O14757	CHEK1	S451	R448Q	448	Missense	distal	-3	no	6.936	-0.271	EPSD	COSMIC	5.604	Loss
CAMK_CAMKL_CHK1_CHEK1_ST	Q02750	MAP2K1	O14757	CHEK1	T55	K57E	57	Missense	proximal	2	no	7.717	7.675	PhosphoSitePlus	COSMIC	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q02750	MAP2K1	O14757	CHEK1	T55	R49L	49	Missense	distal	-6	no	7.717	7.821	PhosphoSitePlus	COSMIC	5.604	Up-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q02750	MAP2K1	O14757	CHEK1	T55	F53Y	53	Missense	proximal	-2	no	7.717	7.539	PhosphoSitePlus	COSMIC	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q02750	MAP2K1	O14757	CHEK1	T55	R49C	49	Missense	distal	-6	no	7.717	7.833	PhosphoSitePlus	COSMIC;GDSC;CCLE	5.604	Up-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q02750	MAP2K1	O14757	CHEK1	T55	L54P	54	Missense	proximal	-1	no	7.717	7.903	PhosphoSitePlus	COSMIC	5.604	Up-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q02750	MAP2K1	O14757	CHEK1	T55	Q58H	58	Missense	distal	3	no	7.717	6.685	PhosphoSitePlus	COSMIC	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q02750	MAP2K1	O14757	CHEK1	T55	T55P	55	Missense	central	0	yes	7.717	0.000	PhosphoSitePlus	COSMIC	5.604	Loss
CAMK_CAMKL_CHK1_CHEK1_ST	Q02750	MAP2K1	O14757	CHEK1	T55	E51G	51	Missense	distal	-4	no	7.717	7.540	PhosphoSitePlus	COSMIC	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q02750	MAP2K1	O14757	CHEK1	T55	V60E	60	Missense	distal	5	no	7.717	7.888	PhosphoSitePlus	COSMIC;GDSC;CCLE	5.604	Up-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q02750	MAP2K1	O14757	CHEK1	T55	V60M	60	Missense	distal	5	no	7.717	7.690	PhosphoSitePlus	COSMIC	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q02750	MAP2K1	O14757	CHEK1	T292	P293S	293	Missense	proximal	1	no	5.758	5.795	EPSD	COSMIC	5.604	Up-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q02750	MAP2K1	O14757	CHEK1	T292	R291K	291	Missense	proximal	-1	no	5.758	5.610	EPSD	COSMIC	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q02750	MAP2K1	O14757	CHEK1	S298	G301E	301	Missense	distal	3	no	7.076	8.623	EPSD	COSMIC	5.604	Up-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q02750	MAP2K1	O14757	CHEK1	S298	P293S	293	Missense	distal	-5	no	7.076	8.595	EPSD	COSMIC	5.604	Up-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q02750	MAP2K1	O14757	CHEK1	S298	R291K	291	Missense	distal	-7	no	7.076	8.256	EPSD	COSMIC	5.604	Up-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	P06400	RB1	O14757	CHEK1	S37	D32N	32	Missense	distal	-5	no	4.871	6.139	EPSD	COSMIC	5.604	Gain
CAMK_CAMKL_CHK1_CHEK1_ST	P06400	RB1	O14757	CHEK1	S83	V81I	81	Missense	proximal	-2	no	6.116	6.052	EPSD	COSMIC	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	P06400	RB1	O14757	CHEK1	S83	K80N	80	Missense	distal	-3	no	6.116	-0.427	EPSD	COSMIC;GDSC;CCLE	5.604	Loss
CAMK_CAMKL_CHK1_CHEK1_ST	P06400	RB1	O14757	CHEK1	S163	S163N	163	Missense	central	0	yes	7.685	0.000	EPSD	COSMIC	5.604	Loss
CAMK_CAMKL_CHK1_CHEK1_ST	P06400	RB1	O14757	CHEK1	S163	L158S	158	Missense	distal	-5	no	7.685	4.497	EPSD	COSMIC	5.604	Loss
CAMK_CAMKL_CHK1_CHEK1_ST	P06400	RB1	O14757	CHEK1	S163	E166K	166	Missense	distal	3	no	7.685	6.869	EPSD	COSMIC	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	P06400	RB1	O14757	CHEK1	S163	A160S	160	Missense	distal	-3	no	7.685	4.700	EPSD	COSMIC	5.604	Loss
CAMK_CAMKL_CHK1_CHEK1_ST	P06400	RB1	O14757	CHEK1	S163	S163I	163	Missense	central	0	yes	7.685	0.000	EPSD	COSMIC	5.604	Loss
CAMK_CAMKL_CHK1_CHEK1_ST	P06400	RB1	O14757	CHEK1	S163	L161F	161	Missense	proximal	-2	no	7.685	7.869	EPSD	COSMIC	5.604	Up-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	P06400	RB1	O14757	CHEK1	S163	D156H	156	Missense	distal	-7	no	7.685	7.596	EPSD	COSMIC	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	P06400	RB1	O14757	CHEK1	S260	Q257R	257	Missense	distal	-3	no	-0.608	6.599	EPSD	COSMIC	5.604	Gain
CAMK_CAMKL_CHK1_CHEK1_ST	P06400	RB1	O14757	CHEK1	S612	R611S	611	Missense	proximal	-1	no	6.544	6.383	PhosphoSitePlus	COSMIC	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	P06400	RB1	O14757	CHEK1	S612	S612P	612	Missense	central	0	yes	6.544	0.000	PhosphoSitePlus	COSMIC	5.604	Loss
CAMK_CAMKL_CHK1_CHEK1_ST	P06400	RB1	O14757	CHEK1	S612	Y606C	606	Missense	distal	-6	no	6.544	6.418	PhosphoSitePlus	COSMIC	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	P06400	RB1	O14757	CHEK1	S612	P609S	609	Missense	distal	-3	no	6.544	3.985	PhosphoSitePlus	COSMIC	5.604	Loss
CAMK_CAMKL_CHK1_CHEK1_ST	P06400	RB1	O14757	CHEK1	S612	M605T	605	Missense	distal	-7	no	6.544	6.078	PhosphoSitePlus	COSMIC	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	P06400	RB1	O14757	CHEK1	S612	L607V	607	Missense	distal	-5	no	6.544	3.067	PhosphoSitePlus	COSMIC	5.604	Loss
CAMK_CAMKL_CHK1_CHEK1_ST	P06400	RB1	O14757	CHEK1	S612	L607I	607	Missense	distal	-5	no	6.544	4.513	PhosphoSitePlus	COSMIC	5.604	Loss
CAMK_CAMKL_CHK1_CHEK1_ST	P06400	RB1	O14757	CHEK1	T619	T620M	620	Missense	proximal	1	no	7.081	7.060	EPSD	COSMIC	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	P06400	RB1	O14757	CHEK1	T619	A626G	626	Missense	distal	7	no	7.081	7.131	EPSD	COSMIC	5.604	Up-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	P06400	RB1	O14757	CHEK1	T619	S612P	612	Missense	distal	-7	no	7.081	6.412	EPSD	COSMIC	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	P06400	RB1	O14757	CHEK1	T619	R621C	621	Missense	proximal	2	no	7.081	6.815	EPSD	COSMIC	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	P06400	RB1	O14757	CHEK1	T619	R621S	621	Missense	proximal	2	no	7.081	7.177	EPSD	COSMIC;GDSC	5.604	Up-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	P06400	RB1	O14757	CHEK1	T619	T625A	625	Missense	distal	6	no	7.081	7.159	EPSD	COSMIC	5.604	Up-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	P06400	RB1	O14757	CHEK1	T619	R621P	621	Missense	proximal	2	no	7.081	7.100	EPSD	COSMIC	5.604	Up-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	P06400	RB1	O14757	CHEK1	S624	Q631K	631	Missense	distal	7	no	11.640	11.560	EPSD	COSMIC	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	P06400	RB1	O14757	CHEK1	S624	T620M	620	Missense	distal	-4	no	11.640	11.836	EPSD	COSMIC	5.604	Up-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	P06400	RB1	O14757	CHEK1	S624	A626G	626	Missense	proximal	2	no	11.640	11.119	EPSD	COSMIC	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	P06400	RB1	O14757	CHEK1	S624	E629K	629	Missense	distal	5	no	11.640	11.575	EPSD	COSMIC	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	P06400	RB1	O14757	CHEK1	S624	R621C	621	Missense	distal	-3	no	11.640	3.549	EPSD	COSMIC	5.604	Loss
CAMK_CAMKL_CHK1_CHEK1_ST	P06400	RB1	O14757	CHEK1	S624	R621S	621	Missense	distal	-3	no	11.640	1.944	EPSD	COSMIC;GDSC	5.604	Loss
CAMK_CAMKL_CHK1_CHEK1_ST	P06400	RB1	O14757	CHEK1	S624	T625A	625	Missense	proximal	1	no	11.640	11.650	EPSD	COSMIC	5.604	Up-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	P06400	RB1	O14757	CHEK1	S624	R621P	621	Missense	distal	-3	no	11.640	4.503	EPSD	COSMIC	5.604	Loss
CAMK_CAMKL_CHK1_CHEK1_ST	P06400	RB1	O14757	CHEK1	T766	T766I	766	Missense	central	0	yes	5.906	0.000	EPSD	COSMIC	5.604	Loss
CAMK_CAMKL_CHK1_CHEK1_ST	P06400	RB1	O14757	CHEK1	T766	A772S	772	Missense	distal	6	no	5.906	5.518	EPSD	COSMIC	5.604	Loss
CAMK_CAMKL_CHK1_CHEK1_ST	P06400	RB1	O14757	CHEK1	T766	I768F	768	Missense	proximal	2	no	5.906	6.268	EPSD	COSMIC	5.604	Up-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	P06400	RB1	O14757	CHEK1	T766	S773F	773	Missense	distal	7	no	5.906	5.476	EPSD	COSMIC	5.604	Loss
CAMK_CAMKL_CHK1_CHEK1_ST	P06400	RB1	O14757	CHEK1	T778	P776R	776	Missense	proximal	-2	no	7.192	7.007	EPSD	COSMIC	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	P06400	RB1	O14757	CHEK1	T778	H784Y	784	Missense	distal	6	no	7.192	7.558	EPSD	COSMIC	5.604	Up-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	P06400	RB1	O14757	CHEK1	T778	A772S	772	Missense	distal	-6	no	7.192	7.319	EPSD	COSMIC	5.604	Up-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	P06400	RB1	O14757	CHEK1	T778	P777S	777	Missense	proximal	-1	no	7.192	6.745	EPSD	COSMIC	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	P06400	RB1	O14757	CHEK1	T778	S773F	773	Missense	distal	-5	no	7.192	6.817	EPSD	COSMIC	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	P19838	NFKB1	O14757	CHEK1	S73	P70H	70	Missense	distal	-3	no	5.133	6.460	EPSD	COSMIC	5.604	Gain
CAMK_CAMKL_CHK1_CHEK1_ST	P19838	NFKB1	O14757	CHEK1	S328	R335W	335	Missense	distal	7	no	8.043	7.542	PhosphoSitePlus	COSMIC	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	P19838	NFKB1	O14757	CHEK1	S337	D338N	338	Missense	proximal	1	no	7.660	7.552	EPSD	COSMIC	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	P19838	NFKB1	O14757	CHEK1	S337	R335W	335	Missense	proximal	-2	no	7.660	7.782	EPSD	COSMIC	5.604	Up-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	P19838	NFKB1	O14757	CHEK1	S899	P905S	905	Missense	distal	6	no	7.058	6.438	EPSD	COSMIC	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	P19838	NFKB1	O14757	CHEK1	S899	S893P	893	Missense	distal	-6	no	7.058	7.155	EPSD	COSMIC	5.604	Up-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	P19838	NFKB1	O14757	CHEK1	S899	S893Y	893	Missense	distal	-6	no	7.058	7.219	EPSD	COSMIC	5.604	Up-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	P19838	NFKB1	O14757	CHEK1	S899	S893F	893	Missense	distal	-6	no	7.058	7.331	EPSD	COSMIC	5.604	Up-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	P19838	NFKB1	O14757	CHEK1	S937	R934H	934	Missense	distal	-3	no	9.519	3.710	EPSD	COSMIC	5.604	Loss
CAMK_CAMKL_CHK1_CHEK1_ST	P19838	NFKB1	O14757	CHEK1	S937	E930K	930	Missense	distal	-7	no	9.519	10.216	EPSD	COSMIC	5.604	Up-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	P19838	NFKB1	O14757	CHEK1	S937	T939I	939	Missense	proximal	2	no	9.519	9.405	EPSD	COSMIC	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q9BXB4	OSBPL11	O14757	CHEK1	S170	S172G	172	Missense	proximal	2	no	5.967	5.902	EPSD	COSMIC	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q9BXB4	OSBPL11	O14757	CHEK1	S174	S172G	172	Missense	proximal	-2	no	11.064	11.197	EPSD	COSMIC	5.604	Up-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q9BXB4	OSBPL11	O14757	CHEK1	S189	S184L	184	Missense	distal	-5	no	9.297	12.485	PhosphoSitePlus	COSMIC;GDSC;CCLE	5.604	Up-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q96RL1	UIMC1	O14757	CHEK1	S12	R15W	15	Missense	distal	3	no	7.956	7.818	EPSD	COSMIC	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q96RL1	UIMC1	O14757	CHEK1	S101	A96T	96	Missense	distal	-5	no	3.262	7.122	EPSD	COSMIC	5.604	Gain
CAMK_CAMKL_CHK1_CHEK1_ST	Q96RL1	UIMC1	O14757	CHEK1	S463	I469M	469	Missense	distal	6	no	10.592	10.951	EPSD	COSMIC	5.604	Up-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q96RL1	UIMC1	O14757	CHEK1	S545	G548V	548	Missense	distal	3	no	5.707	6.133	EPSD	COSMIC	5.604	Up-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q96RL1	UIMC1	O14757	CHEK1	S545	K544I	544	Missense	proximal	-1	no	5.707	5.811	EPSD	COSMIC	5.604	Up-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q96RL1	UIMC1	O14757	CHEK1	S547	G548V	548	Missense	proximal	1	no	6.130	6.107	EPSD	COSMIC	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q96RL1	UIMC1	O14757	CHEK1	S547	K544I	544	Missense	distal	-3	no	6.130	1.198	EPSD	COSMIC	5.604	Loss
CAMK_CAMKL_CHK1_CHEK1_ST	Q96RL1	UIMC1	O14757	CHEK1	S602	E605Q	605	Missense	distal	3	no	11.383	10.983	EPSD	COSMIC;GDSC;CCLE	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q96RL1	UIMC1	O14757	CHEK1	S602	G596R	596	Missense	distal	-6	no	11.383	11.265	EPSD	COSMIC	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q96RL1	UIMC1	O14757	CHEK1	S627	E633G	633	Missense	distal	6	no	7.791	8.274	PhosphoSitePlus	COSMIC	5.604	Up-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q96RL1	UIMC1	O14757	CHEK1	S627	H634Y	634	Missense	distal	7	no	7.791	7.477	PhosphoSitePlus	COSMIC	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q96ST3	SIN3A	O14757	CHEK1	S139	Y144H	144	Missense	distal	5	no	5.638	6.005	EPSD	COSMIC	5.604	Up-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q96ST3	SIN3A	O14757	CHEK1	S295	T292M	292	Missense	distal	-3	no	-6.987	8.434	EPSD	COSMIC	5.604	Gain
CAMK_CAMKL_CHK1_CHEK1_ST	Q96ST3	SIN3A	O14757	CHEK1	T432	G433E	433	Missense	proximal	1	no	9.233	9.316	EPSD	COSMIC	5.604	Up-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q96ST3	SIN3A	O14757	CHEK1	S641	I636V	636	Missense	distal	-5	no	6.078	4.632	EPSD	COSMIC	5.604	Loss
CAMK_CAMKL_CHK1_CHEK1_ST	Q96ST3	SIN3A	O14757	CHEK1	S641	R642C	642	Missense	proximal	1	no	6.078	6.068	EPSD	COSMIC;CCLE	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q96ST3	SIN3A	O14757	CHEK1	S911	L906Q	906	Missense	distal	-5	no	13.347	9.974	EPSD	COSMIC	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q96ST3	SIN3A	O14757	CHEK1	S911	R908Q	908	Missense	distal	-3	no	13.347	6.140	EPSD	COSMIC;CCLE	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q96ST3	SIN3A	O14757	CHEK1	S938	D936G	936	Missense	proximal	-2	no	8.201	8.287	EPSD	COSMIC	5.604	Up-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q96ST3	SIN3A	O14757	CHEK1	S938	S938G	938	Missense	central	0	yes	8.201	0.000	EPSD	COSMIC	5.604	Loss
CAMK_CAMKL_CHK1_CHEK1_ST	Q13470	TNK1	O14757	CHEK1	S68	K73N	73	Missense	distal	5	no	10.801	10.778	EPSD	COSMIC	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q13470	TNK1	O14757	CHEK1	T209	R207H	207	Missense	proximal	-2	no	5.548	5.612	EPSD	COSMIC	5.604	Gain
CAMK_CAMKL_CHK1_CHEK1_ST	Q13470	TNK1	O14757	CHEK1	S500	G498D	498	Missense	proximal	-2	no	5.794	5.708	EPSD	COSMIC	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q13470	TNK1	O14757	CHEK1	S508	G510D	510	Missense	proximal	2	no	5.696	6.228	EPSD	COSMIC	5.604	Up-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q13470	TNK1	O14757	CHEK1	S508	G510S	510	Missense	proximal	2	no	5.696	5.761	EPSD	COSMIC	5.604	Up-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q13470	TNK1	O14757	CHEK1	S508	L509I	509	Missense	proximal	1	no	5.696	5.670	EPSD	COSMIC	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q13470	TNK1	O14757	CHEK1	S508	G510C	510	Missense	proximal	2	no	5.696	5.400	EPSD	COSMIC	5.604	Loss
CAMK_CAMKL_CHK1_CHEK1_ST	Q13470	TNK1	O14757	CHEK1	S508	R512H	512	Missense	distal	4	no	5.696	5.858	EPSD	COSMIC	5.604	Up-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q13470	TNK1	O14757	CHEK1	S550	R554M	554	Missense	distal	4	no	6.088	6.148	EPSD	COSMIC	5.604	Up-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q13470	TNK1	O14757	CHEK1	S550	S545G	545	Missense	distal	-5	no	6.088	6.134	EPSD	COSMIC	5.604	Up-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q32P44	EML3	O14757	CHEK1	S156	S156C	156	Missense	central	0	yes	9.006	0.000	EPSD	COSMIC	5.604	Loss
CAMK_CAMKL_CHK1_CHEK1_ST	Q32P44	EML3	O14757	CHEK1	S156	A149T	149	Missense	distal	-7	no	9.006	7.690	EPSD	COSMIC	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q32P44	EML3	O14757	CHEK1	S156	D150N	150	Missense	distal	-6	no	9.006	9.220	EPSD	COSMIC	5.604	Up-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q32P44	EML3	O14757	CHEK1	S156	S159F	159	Missense	distal	3	no	9.006	9.195	EPSD	COSMIC	5.604	Up-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q32P44	EML3	O14757	CHEK1	S156	S157C	157	Missense	proximal	1	no	9.006	9.022	EPSD	COSMIC	5.604	Up-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q32P44	EML3	O14757	CHEK1	S156	R154Q	154	Missense	proximal	-2	no	9.006	9.052	EPSD	COSMIC	5.604	Up-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q32P44	EML3	O14757	CHEK1	S157	S156C	156	Missense	proximal	-1	no	7.989	8.185	EPSD	COSMIC	5.604	Up-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q32P44	EML3	O14757	CHEK1	S157	D150N	150	Missense	distal	-7	no	7.989	7.681	EPSD	COSMIC	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q32P44	EML3	O14757	CHEK1	S157	S159F	159	Missense	proximal	2	no	7.989	7.844	EPSD	COSMIC	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q32P44	EML3	O14757	CHEK1	S157	S157C	157	Missense	central	0	yes	7.989	0.000	EPSD	COSMIC	5.604	Loss
CAMK_CAMKL_CHK1_CHEK1_ST	Q32P44	EML3	O14757	CHEK1	S157	R154Q	154	Missense	distal	-3	no	7.989	0.782	EPSD	COSMIC	5.604	Loss
CAMK_CAMKL_CHK1_CHEK1_ST	Q32P44	EML3	O14757	CHEK1	S176	S176Y	176	Missense	central	0	yes	8.278	0.000	PhosphoSitePlus	COSMIC	5.604	Loss
CAMK_CAMKL_CHK1_CHEK1_ST	Q32P44	EML3	O14757	CHEK1	S176	S171A	171	Missense	distal	-5	no	8.278	5.550	PhosphoSitePlus	COSMIC	5.604	Loss
CAMK_CAMKL_CHK1_CHEK1_ST	Q32P44	EML3	O14757	CHEK1	S176	S177F	177	Missense	proximal	1	no	8.278	8.273	PhosphoSitePlus	COSMIC	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q32P44	EML3	O14757	CHEK1	S176	A178S	178	Missense	proximal	2	no	8.278	7.822	PhosphoSitePlus	COSMIC	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q32P44	EML3	O14757	CHEK1	S176	S171L	171	Missense	distal	-5	no	8.278	11.466	PhosphoSitePlus	COSMIC	5.604	Up-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q32P44	EML3	O14757	CHEK1	S186	G185R	185	Missense	proximal	-1	no	10.618	10.601	EPSD	COSMIC;CCLE	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q32P44	EML3	O14757	CHEK1	S186	R190C	190	Missense	distal	4	no	10.618	10.722	EPSD	COSMIC	5.604	Up-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q32P44	EML3	O14757	CHEK1	S186	G192R	192	Missense	distal	6	no	10.618	10.494	EPSD	COSMIC	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q32P44	EML3	O14757	CHEK1	S186	R190H	190	Missense	distal	4	no	10.618	10.779	EPSD	COSMIC	5.604	Up-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q32P44	EML3	O14757	CHEK1	S186	T187R	187	Missense	proximal	1	no	10.618	10.636	EPSD	COSMIC	5.604	Up-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q32P44	EML3	O14757	CHEK1	S198	L196V	196	Missense	proximal	-2	no	5.937	6.023	EPSD	COSMIC	5.604	Up-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q32P44	EML3	O14757	CHEK1	S198	R205W	205	Missense	distal	7	no	5.937	5.435	EPSD	COSMIC	5.604	Loss
CAMK_CAMKL_CHK1_CHEK1_ST	Q32P44	EML3	O14757	CHEK1	S198	P199S	199	Missense	proximal	1	no	5.937	5.973	EPSD	COSMIC	5.604	Up-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q32P44	EML3	O14757	CHEK1	S198	S197C	197	Missense	proximal	-1	no	5.937	6.133	EPSD	COSMIC	5.604	Up-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q32P44	EML3	O14757	CHEK1	S198	G192R	192	Missense	distal	-6	no	5.937	5.819	EPSD	COSMIC	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q32P44	EML3	O14757	CHEK1	S198	P202R	202	Missense	distal	4	no	5.937	5.847	EPSD	COSMIC	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q32P44	EML3	O14757	CHEK1	S198	S204Y	204	Missense	distal	6	no	5.937	6.678	EPSD	COSMIC	5.604	Up-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q32P44	EML3	O14757	CHEK1	S198	S198C	198	Missense	central	0	yes	5.937	0.000	EPSD	COSMIC	5.604	Loss
CAMK_CAMKL_CHK1_CHEK1_ST	Q32P44	EML3	O14757	CHEK1	S198	G201V	201	Missense	distal	3	no	5.937	6.363	EPSD	COSMIC	5.604	Up-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q32P44	EML3	O14757	CHEK1	S490	D491N	491	Missense	proximal	1	no	9.058	8.950	EPSD	COSMIC	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q32P44	EML3	O14757	CHEK1	S844	G837V	837	Missense	distal	-7	no	5.660	5.675	EPSD	COSMIC	5.604	Up-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q32P44	EML3	O14757	CHEK1	S887	T881K	881	Missense	distal	-6	no	8.202	8.042	EPSD	COSMIC	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q9Y4F5	CEP170B	O14757	CHEK1	T303	P298L	298	Missense	distal	-5	no	2.476	7.183	EPSD	COSMIC;GDSC	5.604	Gain
CAMK_CAMKL_CHK1_CHEK1_ST	Q9Y4F5	CEP170B	O14757	CHEK1	T358	E355K	355	Missense	distal	-3	no	3.776	7.039	EPSD	COSMIC;GDSC;CCLE	5.604	Gain
CAMK_CAMKL_CHK1_CHEK1_ST	Q9Y4F5	CEP170B	O14757	CHEK1	S421	S425I	425	Missense	distal	4	no	8.973	9.025	EPSD	COSMIC	5.604	Up-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q9Y4F5	CEP170B	O14757	CHEK1	S466	G465S	465	Missense	proximal	-1	no	11.921	11.743	EPSD	COSMIC	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q9Y4F5	CEP170B	O14757	CHEK1	S466	R469Q	469	Missense	distal	3	no	11.921	12.984	EPSD	COSMIC	5.604	Up-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q9Y4F5	CEP170B	O14757	CHEK1	T472	G465S	465	Missense	distal	-7	no	12.226	12.448	EPSD	COSMIC	5.604	Up-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q9Y4F5	CEP170B	O14757	CHEK1	T472	R469Q	469	Missense	distal	-3	no	12.226	5.019	EPSD	COSMIC	5.604	Loss
CAMK_CAMKL_CHK1_CHEK1_ST	Q9Y4F5	CEP170B	O14757	CHEK1	S478	T485P	485	Missense	distal	7	no	11.308	11.430	EPSD	COSMIC	5.604	Up-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q9Y4F5	CEP170B	O14757	CHEK1	S512	R516W	516	Missense	distal	4	no	9.430	9.493	EPSD	COSMIC	5.604	Up-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q9Y4F5	CEP170B	O14757	CHEK1	S512	S512F	512	Missense	central	0	yes	9.430	0.000	EPSD	COSMIC;CCLE	5.604	Loss
CAMK_CAMKL_CHK1_CHEK1_ST	Q9Y4F5	CEP170B	O14757	CHEK1	T531	T531K	531	Missense	central	0	yes	5.646	0.000	EPSD	COSMIC	5.604	Loss
CAMK_CAMKL_CHK1_CHEK1_ST	Q9Y4F5	CEP170B	O14757	CHEK1	T531	V525L	525	Missense	distal	-6	no	5.646	5.659	EPSD	COSMIC	5.604	Up-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q9Y4F5	CEP170B	O14757	CHEK1	T531	P527L	527	Missense	distal	-4	no	5.646	5.462	EPSD	COSMIC	5.604	Loss
CAMK_CAMKL_CHK1_CHEK1_ST	Q9Y4F5	CEP170B	O14757	CHEK1	T531	P529L	529	Missense	proximal	-2	no	5.646	5.467	EPSD	COSMIC	5.604	Loss
CAMK_CAMKL_CHK1_CHEK1_ST	Q9Y4F5	CEP170B	O14757	CHEK1	S605	R609H	609	Missense	distal	4	no	12.206	12.367	EPSD	COSMIC	5.604	Up-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q9Y4F5	CEP170B	O14757	CHEK1	S619	S619C	619	Missense	central	0	yes	7.776	0.000	EPSD	COSMIC	5.604	Loss
CAMK_CAMKL_CHK1_CHEK1_ST	Q9Y4F5	CEP170B	O14757	CHEK1	S619	D620H	620	Missense	proximal	1	no	7.776	7.631	EPSD	COSMIC	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q9Y4F5	CEP170B	O14757	CHEK1	S619	R616K	616	Missense	distal	-3	no	7.776	3.950	EPSD	COSMIC	5.604	Loss
CAMK_CAMKL_CHK1_CHEK1_ST	Q9Y4F5	CEP170B	O14757	CHEK1	S619	D621H	621	Missense	proximal	2	no	7.776	7.233	EPSD	COSMIC	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q9Y4F5	CEP170B	O14757	CHEK1	S636	R637W	637	Missense	proximal	1	no	6.435	6.406	EPSD	COSMIC;CCLE	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q9Y4F5	CEP170B	O14757	CHEK1	S636	P643T	643	Missense	distal	7	no	6.435	6.313	EPSD	COSMIC;CCLE	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q9Y4F5	CEP170B	O14757	CHEK1	S636	P643L	643	Missense	distal	7	no	6.435	6.372	EPSD	COSMIC	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q9Y4F5	CEP170B	O14757	CHEK1	S655	P656L	656	Missense	proximal	1	no	6.178	6.205	PhosphoSitePlus	COSMIC	5.604	Up-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q9Y4F5	CEP170B	O14757	CHEK1	S711	G714S	714	Missense	distal	3	no	7.834	7.921	EPSD	COSMIC	5.604	Up-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q9Y4F5	CEP170B	O14757	CHEK1	S711	P715L	715	Missense	distal	4	no	7.834	7.730	EPSD	COSMIC	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q9Y4F5	CEP170B	O14757	CHEK1	S711	E716D	716	Missense	distal	5	no	7.834	7.835	EPSD	COSMIC	5.604	Up-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q9Y4F5	CEP170B	O14757	CHEK1	S772	S772R	772	Missense	central	0	yes	8.222	0.000	EPSD	COSMIC	5.604	Loss
CAMK_CAMKL_CHK1_CHEK1_ST	Q9Y4F5	CEP170B	O14757	CHEK1	S868	P873L	873	Missense	distal	5	no	8.373	8.211	EPSD	COSMIC	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q9Y4F5	CEP170B	O14757	CHEK1	S875	P873L	873	Missense	proximal	-2	no	6.636	6.457	EPSD	COSMIC	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q9Y4F5	CEP170B	O14757	CHEK1	S875	P878L	878	Missense	distal	3	no	6.636	5.873	EPSD	COSMIC	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q9Y4F5	CEP170B	O14757	CHEK1	S930	D934N	934	Missense	distal	4	no	7.980	7.949	EPSD	COSMIC	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q9Y4F5	CEP170B	O14757	CHEK1	S1057	D1059G	1059	Missense	proximal	2	no	8.934	8.403	EPSD	COSMIC	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q9Y4F5	CEP170B	O14757	CHEK1	S1057	N1064T	1064	Missense	distal	7	no	8.934	8.638	EPSD	COSMIC;GDSC	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q9Y4F5	CEP170B	O14757	CHEK1	S1057	L1055I	1055	Missense	proximal	-2	no	8.934	8.957	EPSD	COSMIC	5.604	Up-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q9Y4F5	CEP170B	O14757	CHEK1	S1057	V1051F	1051	Missense	distal	-6	no	8.934	9.196	EPSD	COSMIC	5.604	Up-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q9Y4F5	CEP170B	O14757	CHEK1	S1057	A1053D	1053	Missense	distal	-4	no	8.934	8.925	EPSD	COSMIC	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q9Y4F5	CEP170B	O14757	CHEK1	S1114	R1119C	1119	Missense	distal	5	no	12.353	12.109	EPSD	COSMIC	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q9Y4F5	CEP170B	O14757	CHEK1	S1165	D1168E	1168	Missense	distal	3	no	6.049	5.952	EPSD	COSMIC	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q9Y4F5	CEP170B	O14757	CHEK1	S1165	I1169S	1169	Missense	distal	4	no	6.049	5.998	EPSD	COSMIC	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q9Y4F5	CEP170B	O14757	CHEK1	S1179	T1183A	1183	Missense	distal	4	no	6.912	7.094	EPSD	COSMIC	5.604	Up-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q9Y4F5	CEP170B	O14757	CHEK1	S1179	A1177T	1177	Missense	proximal	-2	no	6.912	7.051	EPSD	COSMIC	5.604	Up-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q9Y4F5	CEP170B	O14757	CHEK1	S1179	R1176Q	1176	Missense	distal	-3	no	6.912	-0.295	EPSD	COSMIC	5.604	Loss
CAMK_CAMKL_CHK1_CHEK1_ST	Q9Y4F5	CEP170B	O14757	CHEK1	T1210	A1216T	1216	Missense	distal	6	no	7.302	7.224	EPSD	COSMIC	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q9Y4F5	CEP170B	O14757	CHEK1	S1239	R1238H	1238	Missense	proximal	-1	no	6.819	6.945	EPSD	COSMIC	5.604	Up-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q9Y4F5	CEP170B	O14757	CHEK1	S1296	P1299L	1299	Missense	distal	3	no	9.962	9.198	EPSD	COSMIC	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q8WWI1	LMO7	O14757	CHEK1	S56	K58N	58	Missense	proximal	2	no	10.722	10.313	EPSD	COSMIC	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q8WWI1	LMO7	O14757	CHEK1	T117	L122F	122	Missense	distal	5	no	9.164	9.083	EPSD	COSMIC	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q8WWI1	LMO7	O14757	CHEK1	T117	N124D	124	Missense	distal	7	no	9.164	9.326	EPSD	COSMIC	5.604	Up-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q8WWI1	LMO7	O14757	CHEK1	S246	S252C	252	Missense	distal	6	no	8.531	8.913	EPSD	COSMIC	5.604	Up-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q8WWI1	LMO7	O14757	CHEK1	S246	S246F	246	Missense	central	0	yes	8.531	0.000	EPSD	COSMIC	5.604	Loss
CAMK_CAMKL_CHK1_CHEK1_ST	Q8WWI1	LMO7	O14757	CHEK1	S300	R297S	297	Missense	distal	-3	no	9.257	-0.438	EPSD	COSMIC	5.604	Loss
CAMK_CAMKL_CHK1_CHEK1_ST	Q8WWI1	LMO7	O14757	CHEK1	S300	A307V	307	Missense	distal	7	no	9.257	9.337	EPSD	COSMIC	5.604	Up-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q8WWI1	LMO7	O14757	CHEK1	S300	S300L	300	Missense	central	0	yes	9.257	0.000	EPSD	COSMIC	5.604	Loss
CAMK_CAMKL_CHK1_CHEK1_ST	Q8WWI1	LMO7	O14757	CHEK1	S300	A301P	301	Missense	proximal	1	no	9.257	9.203	EPSD	COSMIC	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q8WWI1	LMO7	O14757	CHEK1	S300	S295L	295	Missense	distal	-5	no	9.257	12.445	EPSD	COSMIC	5.604	Up-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q8WWI1	LMO7	O14757	CHEK1	S322	K317T	317	Missense	distal	-5	no	11.502	11.248	EPSD	COSMIC	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q8WWI1	LMO7	O14757	CHEK1	S322	L328M	328	Missense	distal	6	no	11.502	11.494	EPSD	COSMIC	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q8WWI1	LMO7	O14757	CHEK1	S322	S322C	322	Missense	central	0	yes	11.502	0.000	EPSD	COSMIC	5.604	Loss
CAMK_CAMKL_CHK1_CHEK1_ST	Q8WWI1	LMO7	O14757	CHEK1	S322	P315L	315	Missense	distal	-7	no	11.502	11.288	EPSD	COSMIC	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q8WWI1	LMO7	O14757	CHEK1	S322	S318T	318	Missense	distal	-4	no	11.502	11.451	EPSD	COSMIC	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q8WWI1	LMO7	O14757	CHEK1	S392	E386K	386	Missense	distal	-6	no	8.963	8.995	EPSD	COSMIC	5.604	Up-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q8WWI1	LMO7	O14757	CHEK1	S392	R391W	391	Missense	proximal	-1	no	8.963	9.081	EPSD	COSMIC	5.604	Up-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q8WWI1	LMO7	O14757	CHEK1	S407	P408S	408	Missense	proximal	1	no	8.258	8.295	EPSD	COSMIC	5.604	Up-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q8WWI1	LMO7	O14757	CHEK1	S407	P408H	408	Missense	proximal	1	no	8.258	8.255	EPSD	COSMIC	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q8WWI1	LMO7	O14757	CHEK1	T485	R487S	487	Missense	proximal	2	no	7.614	7.709	EPSD	COSMIC	5.604	Up-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q8WWI1	LMO7	O14757	CHEK1	S540	R537K	537	Missense	distal	-3	no	8.736	4.910	EPSD	COSMIC	5.604	Loss
CAMK_CAMKL_CHK1_CHEK1_ST	Q8WWI1	LMO7	O14757	CHEK1	S706	S702L	702	Missense	distal	-4	no	6.000	6.052	EPSD	COSMIC	5.604	Up-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q8WWI1	LMO7	O14757	CHEK1	S706	N700T	700	Missense	distal	-6	no	6.000	6.028	EPSD	COSMIC	5.604	Up-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q8WWI1	LMO7	O14757	CHEK1	S751	S751I	751	Missense	central	0	yes	7.402	0.000	EPSD	COSMIC	5.604	Loss
CAMK_CAMKL_CHK1_CHEK1_ST	Q8WWI1	LMO7	O14757	CHEK1	S751	D747V	747	Missense	distal	-4	no	7.402	7.332	EPSD	COSMIC	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q8WWI1	LMO7	O14757	CHEK1	S751	S754I	754	Missense	distal	3	no	7.402	7.027	EPSD	COSMIC	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q8WWI1	LMO7	O14757	CHEK1	S751	D747E	747	Missense	distal	-4	no	7.402	7.543	EPSD	COSMIC	5.604	Up-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q8WWI1	LMO7	O14757	CHEK1	S751	R748T	748	Missense	distal	-3	no	7.402	-13.167	EPSD	COSMIC	5.604	Loss
CAMK_CAMKL_CHK1_CHEK1_ST	Q8WWI1	LMO7	O14757	CHEK1	S805	S799P	799	Missense	distal	-6	no	9.189	9.286	EPSD	COSMIC	5.604	Up-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q8WWI1	LMO7	O14757	CHEK1	S805	S799L	799	Missense	distal	-6	no	9.189	9.213	EPSD	COSMIC	5.604	Up-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q8WWI1	LMO7	O14757	CHEK1	S805	R801K	801	Missense	distal	-4	no	9.189	9.290	EPSD	COSMIC	5.604	Up-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q8WWI1	LMO7	O14757	CHEK1	S805	R800Q	800	Missense	distal	-5	no	9.189	8.793	EPSD	COSMIC	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q8WWI1	LMO7	O14757	CHEK1	S805	E811K	811	Missense	distal	6	no	9.189	9.459	EPSD	COSMIC	5.604	Up-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q8WWI1	LMO7	O14757	CHEK1	T818	E811K	811	Missense	distal	-7	no	9.464	10.161	EPSD	COSMIC	5.604	Up-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q8WWI1	LMO7	O14757	CHEK1	T818	S825I	825	Missense	distal	7	no	9.464	9.172	EPSD	COSMIC	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q8WWI1	LMO7	O14757	CHEK1	S878	S873L	873	Missense	distal	-5	no	2.591	5.779	EPSD	COSMIC	5.604	Gain
CAMK_CAMKL_CHK1_CHEK1_ST	Q8WWI1	LMO7	O14757	CHEK1	S884	S878N	878	Missense	distal	-6	no	6.625	6.666	EPSD	COSMIC	5.604	Up-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q8WWI1	LMO7	O14757	CHEK1	S884	S878P	878	Missense	distal	-6	no	6.625	6.722	EPSD	COSMIC	5.604	Up-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q8WWI1	LMO7	O14757	CHEK1	S910	R915K	915	Missense	distal	5	no	9.994	10.118	EPSD	COSMIC	5.604	Up-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q8WWI1	LMO7	O14757	CHEK1	S910	S910L	910	Missense	central	0	yes	9.994	0.000	EPSD	COSMIC	5.604	Loss
CAMK_CAMKL_CHK1_CHEK1_ST	Q8WWI1	LMO7	O14757	CHEK1	S910	R907S	907	Missense	distal	-3	no	9.994	0.298	EPSD	COSMIC	5.604	Loss
CAMK_CAMKL_CHK1_CHEK1_ST	Q8WWI1	LMO7	O14757	CHEK1	S971	S968A	968	Missense	distal	-3	no	4.115	7.099	EPSD	COSMIC	5.604	Gain
CAMK_CAMKL_CHK1_CHEK1_ST	Q8WWI1	LMO7	O14757	CHEK1	S988	P989T	989	Missense	proximal	1	no	5.666	5.710	EPSD	COSMIC	5.604	Up-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q8WWI1	LMO7	O14757	CHEK1	S1454	E1457K	1457	Missense	distal	3	no	7.215	6.399	EPSD	COSMIC	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q8WWI1	LMO7	O14757	CHEK1	S1461	E1457K	1457	Missense	distal	-4	no	9.508	9.405	EPSD	COSMIC	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q8WWI1	LMO7	O14757	CHEK1	S1537	T1532A	1532	Missense	distal	-5	no	6.306	2.445	EPSD	COSMIC	5.604	Loss
CAMK_CAMKL_CHK1_CHEK1_ST	Q8WWI1	LMO7	O14757	CHEK1	S1563	R1560H	1560	Missense	distal	-3	no	8.438	2.629	EPSD	COSMIC	5.604	Loss
CAMK_CAMKL_CHK1_CHEK1_ST	Q8WWI1	LMO7	O14757	CHEK1	S1563	R1560C	1560	Missense	distal	-3	no	8.438	0.347	EPSD	COSMIC	5.604	Loss
CAMK_CAMKL_CHK1_CHEK1_ST	Q8WWI1	LMO7	O14757	CHEK1	S1593	S1586C	1586	Missense	distal	-7	no	9.703	8.716	EPSD	COSMIC	5.604	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q9Y6W5	WASF2	P27361	MAPK3	T129	N134K	134	Missense	distal	5	no	13.089	13.059	EPSD	COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q9Y6W5	WASF2	P27361	MAPK3	T137	N134K	134	Missense	distal	-3	no	14.841	14.834	EPSD	COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q9Y6W5	WASF2	P27361	MAPK3	S257	P260S	260	Missense	distal	3	no	16.804	16.799	EPSD	COSMIC;CCLE	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q9Y6W5	WASF2	P27361	MAPK3	S257	S261F	261	Missense	distal	4	no	16.804	16.389	EPSD	COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q9Y6W5	WASF2	P27361	MAPK3	S257	E264K	264	Missense	distal	7	no	16.804	16.874	EPSD	COSMIC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q9Y6W5	WASF2	P27361	MAPK3	S259	P260S	260	Missense	proximal	1	no	16.799	7.745	EPSD	COSMIC;CCLE	9.358	Loss
CMGC_MAPK_ERK1_MAPK3_ST	Q9Y6W5	WASF2	P27361	MAPK3	S259	S261F	261	Missense	proximal	2	no	16.799	16.748	EPSD	COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q9Y6W5	WASF2	P27361	MAPK3	S259	E264K	264	Missense	distal	5	no	16.799	16.671	EPSD	COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q9Y6W5	WASF2	P27361	MAPK3	S296	P302T	302	Missense	distal	6	no	16.695	16.669	EPSD	COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q9Y6W5	WASF2	P27361	MAPK3	S296	R291G	291	Missense	distal	-5	no	16.695	16.697	EPSD	COSMIC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q9Y6W5	WASF2	P27361	MAPK3	S308	P302T	302	Missense	distal	-6	no	17.128	17.044	EPSD	COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q9Y6W5	WASF2	P27361	MAPK3	S308	G315R	315	Missense	distal	7	no	17.128	17.158	EPSD	COSMIC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q9Y6W5	WASF2	P27361	MAPK3	S428	S429F	429	Missense	proximal	1	no	8.290	11.130	EPSD	COSMIC	9.358	Gain
CMGC_MAPK_ERK1_MAPK3_ST	Q9Y6W5	WASF2	P27361	MAPK3	S484	E480K	480	Missense	distal	-4	no	11.190	11.130	EPSD	COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P11388	TOP2A	P27361	MAPK3	S802	M809V	809	Missense	distal	7	no	16.067	15.935	EPSD	COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P11388	TOP2A	P27361	MAPK3	T950	T947I	947	Missense	distal	-3	no	16.507	16.425	EPSD	COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P11388	TOP2A	P27361	MAPK3	T950	T947A	947	Missense	distal	-3	no	16.507	16.445	EPSD	COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P11388	TOP2A	P27361	MAPK3	T950	T950A	950	Missense	central	0	yes	16.507	0.000	EPSD	COSMIC	9.358	Loss
CMGC_MAPK_ERK1_MAPK3_ST	P11388	TOP2A	P27361	MAPK3	S1045	A1046P	1046	Missense	proximal	1	no	5.010	14.250	EPSD	COSMIC	9.358	Gain
CMGC_MAPK_ERK1_MAPK3_ST	P11388	TOP2A	P27361	MAPK3	S1115	K1110E	1110	Missense	distal	-5	no	11.365	11.376	EPSD	COSMIC;GDSC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P11388	TOP2A	P27361	MAPK3	T1124	Y1127C	1127	Missense	distal	3	no	9.508	9.453	EPSD	COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P11388	TOP2A	P27361	MAPK3	S1213	Q1206H	1206	Missense	distal	-7	no	14.675	14.664	EPSD;PhosphoSitePlus	COSMIC;GDSC;CCLE	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P11388	TOP2A	P27361	MAPK3	S1213	Q1206K	1206	Missense	distal	-7	no	14.675	14.676	EPSD;PhosphoSitePlus	COSMIC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P11388	TOP2A	P27361	MAPK3	S1213	P1214S	1214	Missense	proximal	1	no	14.675	5.621	EPSD;PhosphoSitePlus	COSMIC	9.358	Loss
CMGC_MAPK_ERK1_MAPK3_ST	P11388	TOP2A	P27361	MAPK3	S1247	E1242K	1242	Missense	distal	-5	no	16.348	16.336	EPSD;PhosphoSitePlus	COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P11388	TOP2A	P27361	MAPK3	S1377	D1383N	1383	Missense	distal	6	no	9.456	9.403	EPSD	COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P11388	TOP2A	P27361	MAPK3	S1393	V1388L	1388	Missense	distal	-5	no	15.613	15.629	EPSD;PhosphoSitePlus	COSMIC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q07820	MCL1	P27361	MAPK3	S64	G58S	58	Missense	distal	-6	no	16.414	16.477	EPSD	COSMIC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q07820	MCL1	P27361	MAPK3	S64	G59E	59	Missense	distal	-5	no	16.414	16.423	EPSD	COSMIC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q07820	MCL1	P27361	MAPK3	S64	P65L	65	Missense	proximal	1	no	16.414	7.376	EPSD	COSMIC	9.358	Loss
CMGC_MAPK_ERK1_MAPK3_ST	Q07820	MCL1	P27361	MAPK3	S67	D72G	72	Missense	distal	5	no	9.460	9.438	EPSD	COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q07820	MCL1	P27361	MAPK3	S67	P65L	65	Missense	proximal	-2	no	9.460	8.076	EPSD	COSMIC	9.358	Loss
CMGC_MAPK_ERK1_MAPK3_ST	Q07820	MCL1	P27361	MAPK3	T70	D72G	72	Missense	proximal	2	no	16.270	16.265	EPSD	COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q07820	MCL1	P27361	MAPK3	T70	P65L	65	Missense	distal	-5	no	16.270	16.216	EPSD	COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q07820	MCL1	P27361	MAPK3	T70	A77V	77	Missense	distal	7	no	16.270	16.242	EPSD	COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q07820	MCL1	P27361	MAPK3	T92	P93R	93	Missense	proximal	1	no	13.770	4.269	PhosphoSitePlus;EPSD	COSMIC	9.358	Loss
CMGC_MAPK_ERK1_MAPK3_ST	Q07820	MCL1	P27361	MAPK3	T92	F99L	99	Missense	distal	7	no	13.770	13.549	PhosphoSitePlus;EPSD	COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q07820	MCL1	P27361	MAPK3	T92	P87L	87	Missense	distal	-5	no	13.770	13.715	PhosphoSitePlus;EPSD	COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q07820	MCL1	P27361	MAPK3	S121	L126M	126	Missense	distal	5	no	14.022	13.902	EPSD	COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q07820	MCL1	P27361	MAPK3	S121	A116P	116	Missense	distal	-5	no	14.022	14.116	EPSD	COSMIC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q07820	MCL1	P27361	MAPK3	S121	P122L	122	Missense	proximal	1	no	14.022	4.984	EPSD	COSMIC	9.358	Loss
CMGC_MAPK_ERK1_MAPK3_ST	Q07820	MCL1	P27361	MAPK3	T163	E169K	169	Missense	distal	6	no	16.774	16.698	EPSD;PhosphoSitePlus	COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q07820	MCL1	P27361	MAPK3	T163	P161F	161	Missense	proximal	-2	no	16.774	14.398	EPSD;PhosphoSitePlus	COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q07820	MCL1	P27361	MAPK3	T163	P161H	161	Missense	proximal	-2	no	16.774	15.546	EPSD;PhosphoSitePlus	COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q07820	MCL1	P27361	MAPK3	T163	G158R	158	Missense	distal	-5	no	16.774	16.772	EPSD;PhosphoSitePlus	COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q07820	MCL1	P27361	MAPK3	T163	G158D	158	Missense	distal	-5	no	16.774	16.783	EPSD;PhosphoSitePlus	COSMIC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P15056	BRAF	P27361	MAPK3	S151	V157I	157	Missense	distal	6	no	14.464	14.333	EPSD	COSMIC;CCLE	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P15056	BRAF	P27361	MAPK3	S151	S151A	151	Missense	central	0	yes	14.464	0.000	EPSD	COSMIC	9.358	Loss
CMGC_MAPK_ERK1_MAPK3_ST	P15056	BRAF	P27361	MAPK3	S151	P149H	149	Missense	proximal	-2	no	14.464	13.237	EPSD	COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P15056	BRAF	P27361	MAPK3	S317	A322V	322	Missense	distal	5	no	15.604	15.593	EPSD	COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P15056	BRAF	P27361	MAPK3	S317	T310I	310	Missense	distal	-7	no	15.604	15.719	EPSD	COSMIC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P15056	BRAF	P27361	MAPK3	S317	S323L	323	Missense	distal	6	no	15.604	15.248	EPSD	COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P15056	BRAF	P27361	MAPK3	S317	A322T	322	Missense	distal	5	no	15.604	15.724	EPSD	COSMIC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P15056	BRAF	P27361	MAPK3	S317	P321L	321	Missense	distal	4	no	15.604	15.450	EPSD	COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P15056	BRAF	P27361	MAPK3	S317	L312P	312	Missense	distal	-5	no	15.604	15.659	EPSD	COSMIC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P15056	BRAF	P27361	MAPK3	S317	G315V	315	Missense	proximal	-2	no	15.604	16.066	EPSD	COSMIC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P15056	BRAF	P27361	MAPK3	S319	A322V	322	Missense	distal	3	no	11.603	11.609	EPSD	COSMIC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P15056	BRAF	P27361	MAPK3	S319	S323L	323	Missense	distal	4	no	11.603	11.399	EPSD	COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P15056	BRAF	P27361	MAPK3	S319	A322T	322	Missense	distal	3	no	11.603	11.633	EPSD	COSMIC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P15056	BRAF	P27361	MAPK3	S319	I326T	326	Missense	distal	7	no	11.603	11.323	EPSD	COSMIC;GDSC;CCLE	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P15056	BRAF	P27361	MAPK3	S319	P321L	321	Missense	proximal	2	no	11.603	11.581	EPSD	COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P15056	BRAF	P27361	MAPK3	S319	L312P	312	Missense	distal	-7	no	11.603	11.496	EPSD	COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P15056	BRAF	P27361	MAPK3	S319	G315V	315	Missense	distal	-4	no	11.603	11.489	EPSD	COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P15056	BRAF	P27361	MAPK3	S333	T332I	332	Missense	proximal	-1	no	16.812	16.711	EPSD	COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P15056	BRAF	P27361	MAPK3	S333	L331F	331	Missense	proximal	-2	no	16.812	15.820	EPSD	COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P15056	BRAF	P27361	MAPK3	S333	P334S	334	Missense	proximal	1	no	16.812	7.758	EPSD	COSMIC	9.358	Loss
CMGC_MAPK_ERK1_MAPK3_ST	P15056	BRAF	P27361	MAPK3	S333	G327W	327	Missense	distal	-6	no	16.812	16.191	EPSD	COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P15056	BRAF	P27361	MAPK3	S333	S339F	339	Missense	distal	6	no	16.812	16.098	EPSD	COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P15056	BRAF	P27361	MAPK3	S333	I326T	326	Missense	distal	-7	no	16.812	16.697	EPSD	COSMIC;GDSC;CCLE	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P15056	BRAF	P27361	MAPK3	S333	S337L	337	Missense	distal	4	no	16.812	16.608	EPSD	COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P15056	BRAF	P27361	MAPK3	S333	S337P	337	Missense	distal	4	no	16.812	16.763	EPSD	COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P15056	BRAF	P27361	MAPK3	S335	T332I	332	Missense	distal	-3	no	16.219	16.137	EPSD	COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P15056	BRAF	P27361	MAPK3	S335	L331F	331	Missense	distal	-4	no	16.219	16.170	EPSD	COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P15056	BRAF	P27361	MAPK3	S335	P334S	334	Missense	proximal	-1	no	16.219	16.213	EPSD	COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P15056	BRAF	P27361	MAPK3	S335	P341T	341	Missense	distal	6	no	16.219	16.194	EPSD	COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P15056	BRAF	P27361	MAPK3	S335	S339F	339	Missense	distal	4	no	16.219	15.804	EPSD	COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P15056	BRAF	P27361	MAPK3	S335	P341S	341	Missense	distal	6	no	16.219	16.348	EPSD	COSMIC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P15056	BRAF	P27361	MAPK3	S335	S337L	337	Missense	proximal	2	no	16.219	16.195	EPSD	COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P15056	BRAF	P27361	MAPK3	S335	S337P	337	Missense	proximal	2	no	16.219	16.217	EPSD	COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P15056	BRAF	P27361	MAPK3	T401	P407L	407	Missense	distal	6	no	15.379	15.153	PhosphoSitePlus;EPSD	COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P15056	BRAF	P27361	MAPK3	T401	A404V	404	Missense	distal	3	no	15.379	15.386	PhosphoSitePlus;EPSD	COSMIC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P15056	BRAF	P27361	MAPK3	T401	P403L	403	Missense	proximal	2	no	15.379	15.358	PhosphoSitePlus;EPSD	COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P15056	BRAF	P27361	MAPK3	T401	A400S	400	Missense	proximal	-1	no	15.379	15.513	PhosphoSitePlus;EPSD	COSMIC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P15056	BRAF	P27361	MAPK3	S419	G421R	421	Missense	proximal	2	no	14.652	14.657	EPSD	COSMIC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P15056	BRAF	P27361	MAPK3	S419	G421V	421	Missense	proximal	2	no	14.652	14.644	EPSD	COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P15056	BRAF	P27361	MAPK3	S419	V413M	413	Missense	distal	-6	no	14.652	14.560	EPSD	COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P15056	BRAF	P27361	MAPK3	S419	P422A	422	Missense	distal	3	no	14.652	14.604	EPSD	COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P15056	BRAF	P27361	MAPK3	S419	N412S	412	Missense	distal	-7	no	14.652	14.585	EPSD	COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P15056	BRAF	P27361	MAPK3	S419	L416S	416	Missense	distal	-3	no	14.652	14.728	EPSD	COSMIC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P15056	BRAF	P27361	MAPK3	S419	P420S	420	Missense	proximal	1	no	14.652	5.599	EPSD	COSMIC	9.358	Loss
CMGC_MAPK_ERK1_MAPK3_ST	P15056	BRAF	P27361	MAPK3	S419	R424L	424	Missense	distal	5	no	14.652	14.525	EPSD	COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P15056	BRAF	P27361	MAPK3	S467	G469X	469	Missense	proximal	2	no	10.411	10.394	EPSD	COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P15056	BRAF	P27361	MAPK3	S467	G469S	469	Missense	proximal	2	no	10.411	10.428	EPSD	COSMIC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P15056	BRAF	P27361	MAPK3	S467	Y472S	472	Missense	distal	5	no	10.411	10.627	EPSD	COSMIC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P15056	BRAF	P27361	MAPK3	S467	Y472C	472	Missense	distal	5	no	10.411	10.104	EPSD	COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P15056	BRAF	P27361	MAPK3	S467	S467F	467	Missense	central	0	yes	10.411	0.000	EPSD	COSMIC	9.358	Loss
CMGC_MAPK_ERK1_MAPK3_ST	P15056	BRAF	P27361	MAPK3	S467	G464R	464	Missense	distal	-3	no	10.411	10.406	EPSD	COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P15056	BRAF	P27361	MAPK3	S467	G469L	469	Missense	proximal	2	no	10.411	10.404	EPSD	COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P15056	BRAF	P27361	MAPK3	S467	F468S	468	Missense	proximal	1	no	10.411	7.571	EPSD	COSMIC	9.358	Loss
CMGC_MAPK_ERK1_MAPK3_ST	P15056	BRAF	P27361	MAPK3	S467	S465F	465	Missense	proximal	-2	no	10.411	9.111	EPSD	COSMIC	9.358	Loss
CMGC_MAPK_ERK1_MAPK3_ST	P15056	BRAF	P27361	MAPK3	S467	V471A	471	Missense	distal	4	no	10.411	10.303	EPSD	COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P15056	BRAF	P27361	MAPK3	S467	R462I	462	Missense	distal	-5	no	10.411	10.362	EPSD	COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P15056	BRAF	P27361	MAPK3	S467	T470I	470	Missense	distal	3	no	10.411	10.373	EPSD	COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P15056	BRAF	P27361	MAPK3	S467	I463N	463	Missense	distal	-4	no	10.411	10.509	EPSD	COSMIC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P15056	BRAF	P27361	MAPK3	S467	G460R	460	Missense	distal	-7	no	10.411	10.456	EPSD	COSMIC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P15056	BRAF	P27361	MAPK3	S467	F468L	468	Missense	proximal	1	no	10.411	7.587	EPSD	COSMIC	9.358	Loss
CMGC_MAPK_ERK1_MAPK3_ST	P15056	BRAF	P27361	MAPK3	S467	I463S	463	Missense	distal	-4	no	10.411	10.570	EPSD	COSMIC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P15056	BRAF	P27361	MAPK3	S602	R603Q	603	Missense	proximal	1	no	8.078	9.635	EPSD	COSMIC	9.358	Gain
CMGC_MAPK_ERK1_MAPK3_ST	P15056	BRAF	P27361	MAPK3	S675	K680N	680	Missense	distal	5	no	15.482	15.512	EPSD	COSMIC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P15056	BRAF	P27361	MAPK3	S675	P676S	676	Missense	proximal	1	no	15.482	6.429	EPSD	COSMIC	9.358	Loss
CMGC_MAPK_ERK1_MAPK3_ST	P15056	BRAF	P27361	MAPK3	S675	R682W	682	Missense	distal	7	no	15.482	16.059	EPSD	COSMIC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P15056	BRAF	P27361	MAPK3	S675	L674Q	674	Missense	proximal	-1	no	15.482	15.490	EPSD	COSMIC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P15056	BRAF	P27361	MAPK3	S675	R682Q	682	Missense	distal	7	no	15.482	15.512	EPSD	COSMIC;CCLE	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P15056	BRAF	P27361	MAPK3	S675	Y673C	673	Missense	proximal	-2	no	15.482	13.275	EPSD	COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P15056	BRAF	P27361	MAPK3	S675	S679N	679	Missense	distal	4	no	15.482	15.336	EPSD	COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P15056	BRAF	P27361	MAPK3	S750	I755V	755	Missense	distal	5	no	17.108	17.235	EPSD	COSMIC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P15056	BRAF	P27361	MAPK3	S750	C748Y	748	Missense	proximal	-2	no	17.108	19.315	EPSD	COSMIC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P15056	BRAF	P27361	MAPK3	T753	Y760C	760	Missense	distal	7	no	19.962	20.319	EPSD;PhosphoSitePlus	COSMIC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P15056	BRAF	P27361	MAPK3	T753	G759R	759	Missense	distal	6	no	19.962	19.952	EPSD;PhosphoSitePlus	COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P15056	BRAF	P27361	MAPK3	T753	I755V	755	Missense	proximal	2	no	19.962	19.971	EPSD;PhosphoSitePlus	COSMIC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P15056	BRAF	P27361	MAPK3	T753	G758E	758	Missense	distal	5	no	19.962	20.002	EPSD;PhosphoSitePlus	COSMIC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P15056	BRAF	P27361	MAPK3	T753	C748Y	748	Missense	distal	-5	no	19.962	20.060	EPSD;PhosphoSitePlus	COSMIC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P04626	ERBB2	P27361	MAPK3	S196	S189C	189	Missense	distal	-7	no	18.475	18.744	EPSD	COSMIC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P04626	ERBB2	P27361	MAPK3	S196	C195Y	195	Missense	proximal	-1	no	18.475	18.625	EPSD	COSMIC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P04626	ERBB2	P27361	MAPK3	S196	P197L	197	Missense	proximal	1	no	18.475	9.437	EPSD	COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P04626	ERBB2	P27361	MAPK3	S196	P197S	197	Missense	proximal	1	no	18.475	9.421	EPSD	COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P04626	ERBB2	P27361	MAPK3	S196	G201V	201	Missense	distal	5	no	18.475	18.273	EPSD	COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P04626	ERBB2	P27361	MAPK3	S196	K200N	200	Missense	distal	4	no	18.475	18.467	EPSD	COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P04626	ERBB2	P27361	MAPK3	S196	S196P	196	Missense	central	0	yes	18.475	0.000	EPSD	COSMIC	9.358	Loss
CMGC_MAPK_ERK1_MAPK3_ST	P04626	ERBB2	P27361	MAPK3	S196	R190L	190	Missense	distal	-6	no	18.475	18.303	EPSD	COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P04626	ERBB2	P27361	MAPK3	S196	R190Q	190	Missense	distal	-6	no	18.475	18.484	EPSD	COSMIC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P04626	ERBB2	P27361	MAPK3	S196	M198T	198	Missense	proximal	2	no	18.475	18.507	EPSD	COSMIC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P04626	ERBB2	P27361	MAPK3	S196	A191P	191	Missense	distal	-5	no	18.475	18.569	EPSD	COSMIC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P04626	ERBB2	P27361	MAPK3	S196	K200R	200	Missense	distal	4	no	18.475	18.467	EPSD	COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P04626	ERBB2	P27361	MAPK3	S196	A191V	191	Missense	distal	-5	no	18.475	18.498	EPSD	COSMIC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P04626	ERBB2	P27361	MAPK3	S196	A191S	191	Missense	distal	-5	no	18.475	18.574	EPSD	COSMIC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P04626	ERBB2	P27361	MAPK3	T701	E695G	695	Missense	distal	-6	no	18.033	17.987	PhosphoSitePlus	COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P04626	ERBB2	P27361	MAPK3	T701	G704R	704	Missense	distal	3	no	18.033	18.026	PhosphoSitePlus	COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P04626	ERBB2	P27361	MAPK3	T701	P702L	702	Missense	proximal	1	no	18.033	8.995	PhosphoSitePlus	COSMIC	9.358	Loss
CMGC_MAPK_ERK1_MAPK3_ST	P04626	ERBB2	P27361	MAPK3	T701	A705V	705	Missense	distal	4	no	18.033	18.141	PhosphoSitePlus	COSMIC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P04626	ERBB2	P27361	MAPK3	T701	E698V	698	Missense	distal	-3	no	18.033	17.980	PhosphoSitePlus	COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P04626	ERBB2	P27361	MAPK3	T701	P699L	699	Missense	proximal	-2	no	18.033	16.648	PhosphoSitePlus	COSMIC;CCLE	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P04626	ERBB2	P27361	MAPK3	T701	E698K	698	Missense	distal	-3	no	18.033	18.001	PhosphoSitePlus	COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P04626	ERBB2	P27361	MAPK3	T759	S760F	760	Missense	proximal	1	no	7.302	10.142	EPSD	COSMIC	9.358	Gain
CMGC_MAPK_ERK1_MAPK3_ST	P04626	ERBB2	P27361	MAPK3	T759	S760P	760	Missense	proximal	1	no	7.302	16.356	EPSD	COSMIC	9.358	Gain
CMGC_MAPK_ERK1_MAPK3_ST	P04626	ERBB2	P27361	MAPK3	S760	V754M	754	Missense	distal	-6	no	15.436	15.344	EPSD	COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P04626	ERBB2	P27361	MAPK3	S760	L755A	755	Missense	distal	-5	no	15.436	15.397	EPSD	COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P04626	ERBB2	P27361	MAPK3	S760	L755P	755	Missense	distal	-5	no	15.436	15.490	EPSD	COSMIC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P04626	ERBB2	P27361	MAPK3	S760	S760F	760	Missense	central	0	yes	15.436	0.000	EPSD	COSMIC	9.358	Loss
CMGC_MAPK_ERK1_MAPK3_ST	P04626	ERBB2	P27361	MAPK3	S760	E757K	757	Missense	distal	-3	no	15.436	15.405	EPSD	COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P04626	ERBB2	P27361	MAPK3	S760	E757D	757	Missense	distal	-3	no	15.436	15.433	EPSD	COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P04626	ERBB2	P27361	MAPK3	S760	S760P	760	Missense	central	0	yes	15.436	0.000	EPSD	COSMIC	9.358	Loss
CMGC_MAPK_ERK1_MAPK3_ST	P04626	ERBB2	P27361	MAPK3	S760	P761L	761	Missense	proximal	1	no	15.436	6.398	EPSD	COSMIC	9.358	Loss
CMGC_MAPK_ERK1_MAPK3_ST	P04626	ERBB2	P27361	MAPK3	S760	L755R	755	Missense	distal	-5	no	15.436	15.450	EPSD	COSMIC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P04626	ERBB2	P27361	MAPK3	S760	L755F	755	Missense	distal	-5	no	15.436	15.361	EPSD	COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P04626	ERBB2	P27361	MAPK3	S779	L785P	785	Missense	distal	6	no	16.319	16.546	EPSD	COSMIC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P04626	ERBB2	P27361	MAPK3	S779	R784H	784	Missense	distal	5	no	16.319	16.355	EPSD	COSMIC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P04626	ERBB2	P27361	MAPK3	S779	L786M	786	Missense	distal	7	no	16.319	16.500	EPSD	COSMIC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P04626	ERBB2	P27361	MAPK3	S779	G776C	776	Missense	distal	-3	no	16.319	16.174	EPSD	COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P04626	ERBB2	P27361	MAPK3	S779	R784S	784	Missense	distal	5	no	16.319	16.463	EPSD	COSMIC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P04626	ERBB2	P27361	MAPK3	S779	L785R	785	Missense	distal	6	no	16.319	16.434	EPSD	COSMIC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P04626	ERBB2	P27361	MAPK3	S779	S779P	779	Missense	central	0	yes	16.319	0.000	EPSD	COSMIC	9.358	Loss
CMGC_MAPK_ERK1_MAPK3_ST	P04626	ERBB2	P27361	MAPK3	S779	P780L	780	Missense	proximal	1	no	16.319	7.281	EPSD	COSMIC	9.358	Loss
CMGC_MAPK_ERK1_MAPK3_ST	P04626	ERBB2	P27361	MAPK3	S779	V773M	773	Missense	distal	-6	no	16.319	16.227	EPSD	COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P04626	ERBB2	P27361	MAPK3	S779	P780T	780	Missense	proximal	1	no	16.319	7.442	EPSD	COSMIC	9.358	Loss
CMGC_MAPK_ERK1_MAPK3_ST	P04626	ERBB2	P27361	MAPK3	S779	L786V	786	Missense	distal	7	no	16.319	16.367	EPSD	COSMIC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P04626	ERBB2	P27361	MAPK3	S779	Y781C	781	Missense	proximal	2	no	16.319	16.280	EPSD	COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P04626	ERBB2	P27361	MAPK3	S779	L785F	785	Missense	distal	6	no	16.319	15.962	EPSD	COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P04626	ERBB2	P27361	MAPK3	S779	V777E	777	Missense	proximal	-2	no	16.319	16.327	EPSD	COSMIC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P04626	ERBB2	P27361	MAPK3	S779	G778D	778	Missense	proximal	-1	no	16.319	16.338	EPSD	COSMIC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P04626	ERBB2	P27361	MAPK3	S779	V773A	773	Missense	distal	-6	no	16.319	16.332	EPSD	COSMIC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P04626	ERBB2	P27361	MAPK3	S779	P780S	780	Missense	proximal	1	no	16.319	7.266	EPSD	COSMIC	9.358	Loss
CMGC_MAPK_ERK1_MAPK3_ST	P04626	ERBB2	P27361	MAPK3	S779	A775G	775	Missense	distal	-4	no	16.319	16.413	EPSD	COSMIC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P04626	ERBB2	P27361	MAPK3	S779	V782A	782	Missense	distal	3	no	16.319	16.313	EPSD	COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P04626	ERBB2	P27361	MAPK3	S779	G776L	776	Missense	distal	-3	no	16.319	16.276	EPSD	COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P04626	ERBB2	P27361	MAPK3	S779	V782M	782	Missense	distal	3	no	16.319	16.295	EPSD	COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P04626	ERBB2	P27361	MAPK3	S998	P996S	996	Missense	proximal	-2	no	18.499	17.423	EPSD	COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P04626	ERBB2	P27361	MAPK3	S1050	S1051F	1051	Missense	proximal	1	no	8.529	11.368	EPSD	COSMIC	9.358	Gain
CMGC_MAPK_ERK1_MAPK3_ST	P04626	ERBB2	P27361	MAPK3	T1060	L1061P	1061	Missense	proximal	1	no	8.266	17.304	EPSD	COSMIC	9.358	Gain
CMGC_MAPK_ERK1_MAPK3_ST	P04626	ERBB2	P27361	MAPK3	S1073	S1078F	1078	Missense	distal	5	no	17.843	17.418	EPSD	COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P04626	ERBB2	P27361	MAPK3	S1073	P1074A	1074	Missense	proximal	1	no	17.843	8.603	EPSD	COSMIC	9.358	Loss
CMGC_MAPK_ERK1_MAPK3_ST	P04626	ERBB2	P27361	MAPK3	S1107	P1102S	1102	Missense	distal	-5	no	14.208	14.213	EPSD	COSMIC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P04626	ERBB2	P27361	MAPK3	S1107	D1105N	1105	Missense	proximal	-2	no	14.208	13.795	EPSD	COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P04626	ERBB2	P27361	MAPK3	S1107	S1107N	1107	Missense	central	0	yes	14.208	0.000	EPSD	COSMIC	9.358	Loss
CMGC_MAPK_ERK1_MAPK3_ST	P04626	ERBB2	P27361	MAPK3	S1107	E1114G	1114	Missense	distal	7	no	14.208	14.243	EPSD	COSMIC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P04626	ERBB2	P27361	MAPK3	S1107	D1105Y	1105	Missense	proximal	-2	no	14.208	14.506	EPSD	COSMIC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P04626	ERBB2	P27361	MAPK3	S1107	R1111Q	1111	Missense	distal	4	no	14.208	14.164	EPSD	COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P04626	ERBB2	P27361	MAPK3	S1107	E1114Q	1114	Missense	distal	7	no	14.208	14.303	EPSD	COSMIC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P04626	ERBB2	P27361	MAPK3	S1134	A1129V	1129	Missense	distal	-5	no	16.818	16.841	EPSD	COSMIC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P04626	ERBB2	P27361	MAPK3	S1134	C1133S	1133	Missense	proximal	-1	no	16.818	17.045	EPSD	COSMIC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P04626	ERBB2	P27361	MAPK3	S1151	D1144N	1144	Missense	distal	-7	no	17.420	17.445	EPSD	COSMIC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P04626	ERBB2	P27361	MAPK3	S1151	P1156H	1156	Missense	distal	5	no	17.420	17.355	EPSD	COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P04626	ERBB2	P27361	MAPK3	S1151	R1146W	1146	Missense	distal	-5	no	17.420	17.266	EPSD	COSMIC;GDSC;CCLE	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P04626	ERBB2	P27361	MAPK3	S1151	R1153L	1153	Missense	proximal	2	no	17.420	17.409	EPSD	COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P04626	ERBB2	P27361	MAPK3	S1151	D1144H	1144	Missense	distal	-7	no	17.420	17.449	EPSD	COSMIC;GDSC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P04626	ERBB2	P27361	MAPK3	S1151	P1147S	1147	Missense	distal	-4	no	17.420	17.448	EPSD	COSMIC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P04626	ERBB2	P27361	MAPK3	S1151	S1151L	1151	Missense	central	0	yes	17.420	0.000	EPSD	COSMIC	9.358	Loss
CMGC_MAPK_ERK1_MAPK3_ST	P04626	ERBB2	P27361	MAPK3	T1172	L1173P	1173	Missense	proximal	1	no	7.016	16.055	EPSD	COSMIC	9.358	Gain
CMGC_MAPK_ERK1_MAPK3_ST	P04626	ERBB2	P27361	MAPK3	S1174	L1167F	1167	Missense	distal	-7	no	17.467	17.542	EPSD	COSMIC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P04626	ERBB2	P27361	MAPK3	S1174	L1173P	1173	Missense	proximal	-1	no	17.467	17.562	EPSD	COSMIC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P04626	ERBB2	P27361	MAPK3	S1174	S1174F	1174	Missense	central	0	yes	17.467	0.000	EPSD	COSMIC	9.358	Loss
CMGC_MAPK_ERK1_MAPK3_ST	P04626	ERBB2	P27361	MAPK3	S1174	P1170A	1170	Missense	distal	-4	no	17.467	17.363	EPSD	COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P04626	ERBB2	P27361	MAPK3	S1174	G1176W	1176	Missense	proximal	2	no	17.467	17.411	EPSD	COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P04626	ERBB2	P27361	MAPK3	S1174	K1171M	1171	Missense	distal	-3	no	17.467	17.391	EPSD	COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P04626	ERBB2	P27361	MAPK3	S1174	P1175R	1175	Missense	proximal	1	no	17.467	7.967	EPSD	COSMIC	9.358	Loss
CMGC_MAPK_ERK1_MAPK3_ST	P04626	ERBB2	P27361	MAPK3	S1174	K1177E	1177	Missense	distal	3	no	17.467	17.478	EPSD	COSMIC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P04626	ERBB2	P27361	MAPK3	S1174	L1167V	1167	Missense	distal	-7	no	17.467	17.472	EPSD	COSMIC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P04626	ERBB2	P27361	MAPK3	T1198	G1201V	1201	Missense	distal	3	no	15.781	15.759	EPSD	COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P04626	ERBB2	P27361	MAPK3	T1198	G1202V	1202	Missense	distal	4	no	15.781	15.719	EPSD	COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P04626	ERBB2	P27361	MAPK3	T1198	E1195K	1195	Missense	distal	-3	no	15.781	15.750	EPSD	COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P04626	ERBB2	P27361	MAPK3	T1198	L1197F	1197	Missense	proximal	-1	no	15.781	15.666	EPSD	COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P04626	ERBB2	P27361	MAPK3	T1198	V1191M	1191	Missense	distal	-7	no	15.781	15.837	EPSD	COSMIC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P04626	ERBB2	P27361	MAPK3	T1198	Q1200H	1200	Missense	proximal	2	no	15.781	15.788	EPSD	COSMIC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P04626	ERBB2	P27361	MAPK3	T1198	A1204T	1204	Missense	distal	6	no	15.781	16.152	EPSD	COSMIC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P04626	ERBB2	P27361	MAPK3	S1214	P1211H	1211	Missense	distal	-3	no	16.479	16.439	EPSD	COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P04626	ERBB2	P27361	MAPK3	S1214	P1210S	1210	Missense	distal	-4	no	16.479	16.506	EPSD	COSMIC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P04626	ERBB2	P27361	MAPK3	S1214	A1216D	1216	Missense	proximal	2	no	16.479	16.506	EPSD	COSMIC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P04626	ERBB2	P27361	MAPK3	S1214	A1212G	1212	Missense	proximal	-2	no	16.479	16.713	EPSD	COSMIC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P04626	ERBB2	P27361	MAPK3	S1235	E1229Q	1229	Missense	distal	-6	no	11.082	10.947	EPSD	COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P04626	ERBB2	P27361	MAPK3	S1235	T1242M	1242	Missense	distal	7	no	11.082	11.413	EPSD	COSMIC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P04626	ERBB2	P27361	MAPK3	S1235	E1229D	1229	Missense	distal	-6	no	11.082	11.037	EPSD	COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P04626	ERBB2	P27361	MAPK3	S1235	R1230Q	1230	Missense	distal	-5	no	11.082	11.074	EPSD	COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P04626	ERBB2	P27361	MAPK3	S1235	P1233L	1233	Missense	proximal	-2	no	11.082	9.697	EPSD	COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P04626	ERBB2	P27361	MAPK3	T1236	E1229Q	1229	Missense	distal	-7	no	12.477	12.526	EPSD	COSMIC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P04626	ERBB2	P27361	MAPK3	T1236	T1242M	1242	Missense	distal	6	no	12.477	11.983	EPSD	COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P04626	ERBB2	P27361	MAPK3	T1236	E1229D	1229	Missense	distal	-7	no	12.477	12.487	EPSD	COSMIC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P04626	ERBB2	P27361	MAPK3	T1236	R1230Q	1230	Missense	distal	-6	no	12.477	12.486	EPSD	COSMIC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P04626	ERBB2	P27361	MAPK3	T1236	P1233L	1233	Missense	distal	-3	no	12.477	12.393	EPSD	COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P04626	ERBB2	P27361	MAPK3	T1240	N1245D	1245	Missense	distal	5	no	17.623	17.704	EPSD	COSMIC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P04626	ERBB2	P27361	MAPK3	T1240	E1244D	1244	Missense	distal	4	no	17.623	17.604	EPSD	COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P04626	ERBB2	P27361	MAPK3	T1240	T1242M	1242	Missense	proximal	2	no	17.623	17.591	EPSD	COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P04626	ERBB2	P27361	MAPK3	T1240	P1233L	1233	Missense	distal	-7	no	17.623	17.730	EPSD	COSMIC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P04626	ERBB2	P27361	MAPK3	T1242	N1245D	1245	Missense	distal	3	no	10.287	10.297	EPSD	COSMIC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P04626	ERBB2	P27361	MAPK3	T1242	E1244D	1244	Missense	proximal	2	no	10.287	10.284	EPSD	COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P04626	ERBB2	P27361	MAPK3	T1242	T1242M	1242	Missense	central	0	yes	10.287	0.000	EPSD	COSMIC	9.358	Loss
CMGC_MAPK_ERK1_MAPK3_ST	P10636	MAPT	P27361	MAPK3	T69	E62K	62	Missense	distal	-7	no	15.297	15.348	EPSD	COSMIC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P10636	MAPT	P27361	MAPK3	T111	I108V	108	Missense	distal	-3	no	15.249	15.288	EPSD	COSMIC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P10636	MAPT	P27361	MAPK3	T111	G107R	107	Missense	distal	-4	no	15.249	15.211	EPSD	COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P10636	MAPT	P27361	MAPK3	S228	S227N	227	Missense	proximal	-1	no	17.196	17.147	EPSD	COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P10636	MAPT	P27361	MAPK3	S228	S227I	227	Missense	proximal	-1	no	17.196	17.064	EPSD	COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P10636	MAPT	P27361	MAPK3	S228	E226K	226	Missense	proximal	-2	no	17.196	16.501	EPSD	COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P10636	MAPT	P27361	MAPK3	S228	Q230R	230	Missense	proximal	2	no	17.196	17.205	EPSD	COSMIC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P10636	MAPT	P27361	MAPK3	S228	P233S	233	Missense	distal	5	no	17.196	17.239	EPSD	COSMIC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P10636	MAPT	P27361	MAPK3	S228	D225E	225	Missense	distal	-3	no	17.196	17.199	EPSD	COSMIC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P10636	MAPT	P27361	MAPK3	S228	S227G	227	Missense	proximal	-1	no	17.196	17.130	EPSD	COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P10636	MAPT	P27361	MAPK3	S228	S235L	235	Missense	distal	7	no	17.196	17.465	EPSD	COSMIC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P10636	MAPT	P27361	MAPK3	S232	S227N	227	Missense	distal	-5	no	16.576	16.536	EPSD	COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P10636	MAPT	P27361	MAPK3	S232	S227I	227	Missense	distal	-5	no	16.576	16.482	EPSD	COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P10636	MAPT	P27361	MAPK3	S232	A237T	237	Missense	distal	5	no	16.576	16.696	EPSD	COSMIC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P10636	MAPT	P27361	MAPK3	S232	E226K	226	Missense	distal	-6	no	16.576	16.434	EPSD	COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P10636	MAPT	P27361	MAPK3	S232	Q230R	230	Missense	proximal	-2	no	16.576	16.940	EPSD	COSMIC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P10636	MAPT	P27361	MAPK3	S232	S238P	238	Missense	distal	6	no	16.576	16.446	EPSD	COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P10636	MAPT	P27361	MAPK3	S232	P233S	233	Missense	proximal	1	no	16.576	7.523	EPSD	COSMIC	9.358	Loss
CMGC_MAPK_ERK1_MAPK3_ST	P10636	MAPT	P27361	MAPK3	S232	S238F	238	Missense	distal	6	no	16.576	15.862	EPSD	COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P10636	MAPT	P27361	MAPK3	S232	D225E	225	Missense	distal	-7	no	16.576	16.566	EPSD	COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P10636	MAPT	P27361	MAPK3	S232	S227G	227	Missense	distal	-5	no	16.576	16.533	EPSD	COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P10636	MAPT	P27361	MAPK3	S232	S235L	235	Missense	distal	3	no	16.576	16.544	EPSD	COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P10636	MAPT	P27361	MAPK3	S238	A237T	237	Missense	proximal	-1	no	16.113	16.216	EPSD	COSMIC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P10636	MAPT	P27361	MAPK3	S238	A240S	240	Missense	proximal	2	no	16.113	16.152	EPSD	COSMIC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P10636	MAPT	P27361	MAPK3	S238	D242N	242	Missense	distal	4	no	16.113	16.086	EPSD	COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P10636	MAPT	P27361	MAPK3	S238	R244W	244	Missense	distal	6	no	16.113	15.290	EPSD	COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P10636	MAPT	P27361	MAPK3	S238	S238P	238	Missense	central	0	yes	16.113	0.000	EPSD	COSMIC	9.358	Loss
CMGC_MAPK_ERK1_MAPK3_ST	P10636	MAPT	P27361	MAPK3	S238	P233S	233	Missense	distal	-5	no	16.113	16.118	EPSD	COSMIC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P10636	MAPT	P27361	MAPK3	S238	S238F	238	Missense	central	0	yes	16.113	0.000	EPSD	COSMIC	9.358	Loss
CMGC_MAPK_ERK1_MAPK3_ST	P10636	MAPT	P27361	MAPK3	S238	G243D	243	Missense	distal	5	no	16.113	16.136	EPSD	COSMIC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P10636	MAPT	P27361	MAPK3	S238	S235L	235	Missense	distal	-3	no	16.113	16.037	EPSD	COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P10636	MAPT	P27361	MAPK3	S411	L410F	410	Missense	proximal	-1	no	14.840	14.725	EPSD	COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P10636	MAPT	P27361	MAPK3	S411	P412S	412	Missense	proximal	1	no	14.840	5.787	EPSD	COSMIC	9.358	Loss
CMGC_MAPK_ERK1_MAPK3_ST	P10636	MAPT	P27361	MAPK3	T416	L410F	410	Missense	distal	-6	no	14.703	14.568	EPSD	COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P10636	MAPT	P27361	MAPK3	T416	P412S	412	Missense	distal	-4	no	14.703	14.730	EPSD	COSMIC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P10636	MAPT	P27361	MAPK3	S438	S443Y	443	Missense	distal	5	no	20.015	19.799	EPSD	COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P10636	MAPT	P27361	MAPK3	T470	T466M	466	Missense	distal	-4	no	14.131	14.009	EPSD	COSMIC;GDSC;CCLE	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P10636	MAPT	P27361	MAPK3	T470	K467T	467	Missense	distal	-3	no	14.131	14.151	EPSD	COSMIC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P10636	MAPT	P27361	MAPK3	T470	P477L	477	Missense	distal	7	no	14.131	14.323	EPSD	COSMIC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P10636	MAPT	P27361	MAPK3	T470	P477S	477	Missense	distal	7	no	14.131	14.053	EPSD	COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P10636	MAPT	P27361	MAPK3	T492	K491R	491	Missense	proximal	-1	no	13.516	13.530	EPSD	COSMIC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P10636	MAPT	P27361	MAPK3	T492	R487G	487	Missense	distal	-5	no	13.516	13.519	EPSD	COSMIC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P10636	MAPT	P27361	MAPK3	T492	A495T	495	Missense	distal	3	no	13.516	13.547	EPSD	COSMIC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P10636	MAPT	P27361	MAPK3	T492	P493L	493	Missense	proximal	1	no	13.516	4.478	EPSD	COSMIC	9.358	Loss
CMGC_MAPK_ERK1_MAPK3_ST	P10636	MAPT	P27361	MAPK3	T498	K491R	491	Missense	distal	-7	no	16.656	16.655	EPSD	COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P10636	MAPT	P27361	MAPK3	T498	A495T	495	Missense	distal	-3	no	16.656	16.717	EPSD	COSMIC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P10636	MAPT	P27361	MAPK3	T498	P493L	493	Missense	distal	-5	no	16.656	16.601	EPSD	COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P10636	MAPT	P27361	MAPK3	S516	G521V	521	Missense	distal	5	no	17.816	17.614	EPSD	COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P10636	MAPT	P27361	MAPK3	S516	G518V	518	Missense	proximal	2	no	17.816	17.807	EPSD	COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P10636	MAPT	P27361	MAPK3	S516	R511C	511	Missense	distal	-5	no	17.816	17.700	EPSD	COSMIC;CCLE	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P10636	MAPT	P27361	MAPK3	S516	G509V	509	Missense	distal	-7	no	17.816	17.927	EPSD	COSMIC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P10636	MAPT	P27361	MAPK3	S519	G521V	521	Missense	proximal	2	no	18.268	18.259	EPSD	COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P10636	MAPT	P27361	MAPK3	S519	R526H	526	Missense	distal	7	no	18.268	18.235	EPSD	COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P10636	MAPT	P27361	MAPK3	S519	G518V	518	Missense	proximal	-1	no	18.268	18.249	EPSD	COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P10636	MAPT	P27361	MAPK3	T522	G521V	521	Missense	proximal	-1	no	17.797	17.779	EPSD	COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P10636	MAPT	P27361	MAPK3	T522	R526H	526	Missense	distal	4	no	17.797	17.803	EPSD	COSMIC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P10636	MAPT	P27361	MAPK3	T522	G518V	518	Missense	distal	-4	no	17.797	17.683	EPSD	COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P10636	MAPT	P27361	MAPK3	T522	R528S	528	Missense	distal	6	no	17.797	18.039	EPSD	COSMIC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P10636	MAPT	P27361	MAPK3	S525	R526H	526	Missense	proximal	1	no	9.028	10.773	EPSD	COSMIC	9.358	Gain
CMGC_MAPK_ERK1_MAPK3_ST	P10636	MAPT	P27361	MAPK3	T529	R526H	526	Missense	distal	-3	no	14.948	14.954	EPSD	COSMIC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P10636	MAPT	P27361	MAPK3	T529	R528S	528	Missense	proximal	-1	no	14.948	14.990	EPSD	COSMIC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P10636	MAPT	P27361	MAPK3	T529	P530S	530	Missense	proximal	1	no	14.948	5.895	EPSD	COSMIC	9.358	Loss
CMGC_MAPK_ERK1_MAPK3_ST	P10636	MAPT	P27361	MAPK3	T529	P536H	536	Missense	distal	7	no	14.948	15.008	EPSD	COSMIC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P10636	MAPT	P27361	MAPK3	T529	P535Q	535	Missense	distal	6	no	14.948	14.767	EPSD	COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P10636	MAPT	P27361	MAPK3	T534	R528S	528	Missense	distal	-6	no	15.838	15.999	EPSD	COSMIC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P10636	MAPT	P27361	MAPK3	T534	P530S	530	Missense	distal	-4	no	15.838	15.866	EPSD	COSMIC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P10636	MAPT	P27361	MAPK3	T534	P536H	536	Missense	proximal	2	no	15.838	15.825	EPSD	COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P10636	MAPT	P27361	MAPK3	T534	P535Q	535	Missense	proximal	1	no	15.838	7.895	EPSD	COSMIC	9.358	Loss
CMGC_MAPK_ERK1_MAPK3_ST	P10636	MAPT	P27361	MAPK3	T534	E539Q	539	Missense	distal	5	no	15.838	15.717	EPSD	COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P10636	MAPT	P27361	MAPK3	T548	P550S	550	Missense	proximal	2	no	15.971	15.973	EPSD	COSMIC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P10636	MAPT	P27361	MAPK3	T548	P553R	553	Missense	distal	5	no	15.971	15.871	EPSD	COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P10636	MAPT	P27361	MAPK3	T548	P553L	553	Missense	distal	5	no	15.971	15.743	EPSD	COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P10636	MAPT	P27361	MAPK3	T548	P549L	549	Missense	proximal	1	no	15.971	6.933	EPSD	COSMIC	9.358	Loss
CMGC_MAPK_ERK1_MAPK3_ST	P10636	MAPT	P27361	MAPK3	T548	S555F	555	Missense	distal	7	no	15.971	16.462	EPSD	COSMIC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P10636	MAPT	P27361	MAPK3	T548	P553Q	553	Missense	distal	5	no	15.971	15.869	EPSD	COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P10636	MAPT	P27361	MAPK3	S552	P550S	550	Missense	proximal	-2	no	17.740	16.664	EPSD	COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P10636	MAPT	P27361	MAPK3	S552	R559C	559	Missense	distal	7	no	17.740	18.182	EPSD	COSMIC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P10636	MAPT	P27361	MAPK3	S552	P553R	553	Missense	proximal	1	no	17.740	8.239	EPSD	COSMIC	9.358	Loss
CMGC_MAPK_ERK1_MAPK3_ST	P10636	MAPT	P27361	MAPK3	S552	P553L	553	Missense	proximal	1	no	17.740	8.702	EPSD	COSMIC	9.358	Loss
CMGC_MAPK_ERK1_MAPK3_ST	P10636	MAPT	P27361	MAPK3	S552	P549L	549	Missense	distal	-3	no	17.740	17.656	EPSD	COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P10636	MAPT	P27361	MAPK3	S552	S555F	555	Missense	distal	3	no	17.740	17.675	EPSD	COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P10636	MAPT	P27361	MAPK3	S552	P553Q	553	Missense	proximal	1	no	17.740	9.796	EPSD	COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P10636	MAPT	P27361	MAPK3	S554	S555F	555	Missense	proximal	1	no	6.676	9.516	EPSD	COSMIC	9.358	Gain
CMGC_MAPK_ERK1_MAPK3_ST	P10636	MAPT	P27361	MAPK3	S713	G706R	706	Missense	distal	-7	no	17.918	17.963	EPSD	COSMIC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P10636	MAPT	P27361	MAPK3	S713	V710M	710	Missense	distal	-3	no	17.918	17.863	EPSD	COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P10636	MAPT	P27361	MAPK3	S713	E708K	708	Missense	distal	-5	no	17.918	17.906	EPSD	COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P10636	MAPT	P27361	MAPK3	S713	V710A	710	Missense	distal	-3	no	17.918	17.898	EPSD	COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P10636	MAPT	P27361	MAPK3	S721	R723W	723	Missense	proximal	2	no	16.315	16.255	EPSD	COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P10636	MAPT	P27361	MAPK3	S721	V728M	728	Missense	distal	7	no	16.315	16.447	EPSD	COSMIC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P10636	MAPT	P27361	MAPK3	S721	V728A	728	Missense	distal	7	no	16.315	16.343	EPSD	COSMIC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P10636	MAPT	P27361	MAPK3	S739	G732S	732	Missense	distal	-7	no	19.967	19.929	EPSD	COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P10636	MAPT	P27361	MAPK3	S739	D735N	735	Missense	distal	-4	no	19.967	19.941	EPSD	COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P10636	MAPT	P27361	MAPK3	S739	G732C	732	Missense	distal	-7	no	19.967	20.198	EPSD	COSMIC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P10636	MAPT	P27361	MAPK3	S739	T744M	744	Missense	distal	5	no	19.967	19.711	EPSD	COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P10636	MAPT	P27361	MAPK3	S739	A743T	743	Missense	distal	4	no	19.967	20.185	EPSD	COSMIC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P10636	MAPT	P27361	MAPK3	T744	E748K	748	Missense	distal	4	no	9.660	9.621	EPSD	COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P10636	MAPT	P27361	MAPK3	T744	T744M	744	Missense	central	0	yes	9.660	0.000	EPSD	COSMIC	9.358	Loss
CMGC_MAPK_ERK1_MAPK3_ST	P10636	MAPT	P27361	MAPK3	T744	A743T	743	Missense	proximal	-1	no	9.660	9.763	EPSD	COSMIC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P10636	MAPT	P27361	MAPK3	S752	E748K	748	Missense	distal	-4	no	10.482	10.422	EPSD	COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q13541	EIF4EBP1	P27361	MAPK3	S65	L59Q	59	Missense	distal	-6	no	14.573	14.754	PhosphoSitePlus	COSMIC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q13541	EIF4EBP1	P27361	MAPK3	S65	M60I	60	Missense	distal	-5	no	14.573	14.597	PhosphoSitePlus	COSMIC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q13541	EIF4EBP1	P27361	MAPK3	S65	P72S	72	Missense	distal	7	no	14.573	14.495	PhosphoSitePlus	COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q13541	EIF4EBP1	P27361	MAPK3	S65	R63W	63	Missense	proximal	-2	no	14.573	12.676	PhosphoSitePlus	COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q13541	EIF4EBP1	P27361	MAPK3	T70	P72S	72	Missense	proximal	2	no	16.526	16.528	EPSD	COSMIC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q13541	EIF4EBP1	P27361	MAPK3	T70	R63W	63	Missense	distal	-7	no	16.526	16.772	EPSD	COSMIC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q13541	EIF4EBP1	P27361	MAPK3	S83	S85F	85	Missense	proximal	2	no	15.837	15.787	EPSD	COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q13541	EIF4EBP1	P27361	MAPK3	S86	S85F	85	Missense	proximal	-1	no	11.448	11.244	EPSD	COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q13541	EIF4EBP1	P27361	MAPK3	S94	N100H	100	Missense	distal	6	no	10.288	10.294	EPSD	COSMIC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q13541	EIF4EBP1	P27361	MAPK3	S96	N100H	100	Missense	distal	4	no	11.635	11.641	EPSD	COSMIC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q13541	EIF4EBP1	P27361	MAPK3	S101	N100H	100	Missense	proximal	-1	no	17.868	17.877	EPSD	COSMIC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q13541	EIF4EBP1	P27361	MAPK3	S101	R106L	106	Missense	distal	5	no	17.868	17.741	EPSD	COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q13541	EIF4EBP1	P27361	MAPK3	S112	R106L	106	Missense	distal	-6	no	10.620	10.449	EPSD	COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P49715	CEBPA	P27361	MAPK3	S17	S21G	21	Missense	distal	4	no	9.965	9.804	EPSD	COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P49715	CEBPA	P27361	MAPK3	S17	S21R	21	Missense	distal	4	no	9.965	9.818	EPSD	COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P49715	CEBPA	P27361	MAPK3	S17	L19Q	19	Missense	proximal	2	no	9.965	9.966	EPSD	COSMIC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P49715	CEBPA	P27361	MAPK3	S17	P14R	14	Missense	distal	-3	no	9.965	9.919	EPSD	COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P49715	CEBPA	P27361	MAPK3	S17	E10K	10	Missense	distal	-7	no	9.965	10.016	EPSD	COSMIC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P49715	CEBPA	P27361	MAPK3	S17	P14L	14	Missense	distal	-3	no	9.965	9.881	EPSD	COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P49715	CEBPA	P27361	MAPK3	S21	S21G	21	Missense	central	0	yes	17.921	0.000	PhosphoSitePlus	COSMIC	9.358	Loss
CMGC_MAPK_ERK1_MAPK3_ST	P49715	CEBPA	P27361	MAPK3	S21	S21R	21	Missense	central	0	yes	17.921	0.000	PhosphoSitePlus	COSMIC	9.358	Loss
CMGC_MAPK_ERK1_MAPK3_ST	P49715	CEBPA	P27361	MAPK3	S21	L19Q	19	Missense	proximal	-2	no	17.921	17.541	PhosphoSitePlus	COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P49715	CEBPA	P27361	MAPK3	S21	S27R	27	Missense	distal	6	no	17.921	17.679	PhosphoSitePlus	COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P49715	CEBPA	P27361	MAPK3	S21	P14R	14	Missense	distal	-7	no	17.921	17.966	PhosphoSitePlus	COSMIC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P49715	CEBPA	P27361	MAPK3	S21	P14L	14	Missense	distal	-7	no	17.921	18.028	PhosphoSitePlus	COSMIC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P49715	CEBPA	P27361	MAPK3	S190	P184R	184	Missense	distal	-6	no	10.568	10.493	EPSD	COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P49715	CEBPA	P27361	MAPK3	S190	P186S	186	Missense	distal	-4	no	10.568	10.596	EPSD	COSMIC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P49715	CEBPA	P27361	MAPK3	S190	P183Q	183	Missense	distal	-7	no	10.568	10.613	EPSD	COSMIC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P49715	CEBPA	P27361	MAPK3	S190	P197Q	197	Missense	distal	7	no	10.568	10.690	EPSD	COSMIC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P49715	CEBPA	P27361	MAPK3	T226	G223S	223	Missense	distal	-3	no	13.568	13.601	EPSD	COSMIC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P49715	CEBPA	P27361	MAPK3	T226	P227S	227	Missense	proximal	1	no	13.568	4.515	EPSD	COSMIC	9.358	Loss
CMGC_MAPK_ERK1_MAPK3_ST	P49715	CEBPA	P27361	MAPK3	T226	G223R	223	Missense	distal	-3	no	13.568	13.563	EPSD	COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P49715	CEBPA	P27361	MAPK3	T226	H224Q	224	Missense	proximal	-2	no	13.568	13.032	EPSD	COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P49715	CEBPA	P27361	MAPK3	T226	P233R	233	Missense	distal	7	no	13.568	13.660	EPSD	COSMIC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P49715	CEBPA	P27361	MAPK3	T230	G223S	223	Missense	distal	-7	no	16.495	16.457	EPSD	COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P49715	CEBPA	P27361	MAPK3	T230	P227S	227	Missense	distal	-3	no	16.495	16.487	EPSD	COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P49715	CEBPA	P27361	MAPK3	T230	G223R	223	Missense	distal	-7	no	16.495	16.540	EPSD	COSMIC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P49715	CEBPA	P27361	MAPK3	T230	H224Q	224	Missense	distal	-6	no	16.495	16.509	EPSD	COSMIC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P49715	CEBPA	P27361	MAPK3	T230	P233R	233	Missense	distal	3	no	16.495	16.468	EPSD	COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P49715	CEBPA	P27361	MAPK3	S234	P239A	239	Missense	distal	5	no	15.675	15.463	EPSD	COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P49715	CEBPA	P27361	MAPK3	S234	P227S	227	Missense	distal	-7	no	15.675	15.637	EPSD	COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P49715	CEBPA	P27361	MAPK3	S234	P233R	233	Missense	proximal	-1	no	15.675	15.627	EPSD	COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P49715	CEBPA	P27361	MAPK3	S332	T337M	337	Missense	distal	5	no	10.348	10.093	EPSD	COSMIC;GDSC;CCLE	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P49715	CEBPA	P27361	MAPK3	S332	T337S	337	Missense	distal	5	no	10.348	10.484	EPSD	COSMIC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P49715	CEBPA	P27361	MAPK3	S332	L331Q	331	Missense	proximal	-1	no	10.348	10.357	EPSD	COSMIC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P49715	CEBPA	P27361	MAPK3	S332	L335Q	335	Missense	distal	3	no	10.348	10.358	EPSD	COSMIC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P49715	CEBPA	P27361	MAPK3	S332	L338P	338	Missense	distal	6	no	10.348	10.575	EPSD	COSMIC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P49715	CEBPA	P27361	MAPK3	S332	R339P	339	Missense	distal	7	no	10.348	10.256	EPSD	COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P49715	CEBPA	P27361	MAPK3	S332	R333P	333	Missense	proximal	1	no	10.348	19.849	EPSD	COSMIC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q16828	DUSP6	P27361	MAPK3	S159	G166V	166	Missense	distal	7	no	16.518	16.697	EPSD;PhosphoSitePlus	COSMIC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q16828	DUSP6	P27361	MAPK3	S159	C155R	155	Missense	distal	-4	no	16.518	16.679	EPSD;PhosphoSitePlus	COSMIC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q16828	DUSP6	P27361	MAPK3	S159	L165F	165	Missense	distal	6	no	16.518	16.161	EPSD;PhosphoSitePlus	COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q16828	DUSP6	P27361	MAPK3	S197	T192A	192	Missense	distal	-5	no	17.628	17.545	EPSD;PhosphoSitePlus	COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q16828	DUSP6	P27361	MAPK3	S197	P198L	198	Missense	proximal	1	no	17.628	8.590	EPSD;PhosphoSitePlus	COSMIC	9.358	Loss
CMGC_MAPK_ERK1_MAPK3_ST	Q16828	DUSP6	P27361	MAPK3	S197	D193Y	193	Missense	distal	-4	no	17.628	17.560	EPSD;PhosphoSitePlus	COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q16828	DUSP6	P27361	MAPK3	S197	S190L	190	Missense	distal	-7	no	17.628	17.773	EPSD;PhosphoSitePlus	COSMIC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q16828	DUSP6	P27361	MAPK3	S197	D193H	193	Missense	distal	-4	no	17.628	17.600	EPSD;PhosphoSitePlus	COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q16828	DUSP6	P27361	MAPK3	S205	P198L	198	Missense	distal	-7	no	9.420	9.527	EPSD	COSMIC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q16828	DUSP6	P27361	MAPK3	S205	P207Q	207	Missense	proximal	2	no	9.420	9.400	EPSD	COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q16828	DUSP6	P27361	MAPK3	S205	P212L	212	Missense	distal	7	no	9.420	9.613	EPSD	COSMIC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q16828	DUSP6	P27361	MAPK3	S331	G338S	338	Missense	distal	7	no	14.771	14.632	EPSD	COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q16828	DUSP6	P27361	MAPK3	S331	M325L	325	Missense	distal	-6	no	14.771	14.861	EPSD	COSMIC;CCLE	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q16828	DUSP6	P27361	MAPK3	S331	M337L	337	Missense	distal	6	no	14.771	15.064	EPSD	COSMIC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q16828	DUSP6	P27361	MAPK3	S351	P358L	358	Missense	distal	7	no	16.986	17.179	EPSD	COSMIC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P41235	HNF4A	P27361	MAPK3	S142	R140Q	140	Missense	proximal	-2	no	9.379	9.015	EPSD;PhosphoSitePlus	COSMIC;GDSC;CCLE	9.358	Loss
CMGC_MAPK_ERK1_MAPK3_ST	P41235	HNF4A	P27361	MAPK3	S142	S148F	148	Missense	distal	6	no	9.379	8.665	EPSD;PhosphoSitePlus	COSMIC	9.358	Loss
CMGC_MAPK_ERK1_MAPK3_ST	P41235	HNF4A	P27361	MAPK3	S142	R141G	141	Missense	proximal	-1	no	9.379	9.354	EPSD;PhosphoSitePlus	COSMIC	9.358	Loss
CMGC_MAPK_ERK1_MAPK3_ST	P41235	HNF4A	P27361	MAPK3	S142	R141Q	141	Missense	proximal	-1	no	9.379	9.340	EPSD;PhosphoSitePlus	COSMIC	9.358	Loss
CMGC_MAPK_ERK1_MAPK3_ST	P41235	HNF4A	P27361	MAPK3	S147	S148F	148	Missense	proximal	1	no	8.136	10.975	EPSD;PhosphoSitePlus	COSMIC	9.358	Gain
CMGC_MAPK_ERK1_MAPK3_ST	P41235	HNF4A	P27361	MAPK3	S167	Q164H	164	Missense	distal	-3	no	14.115	14.129	EPSD;PhosphoSitePlus	COSMIC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P41235	HNF4A	P27361	MAPK3	S167	G171R	171	Missense	distal	4	no	14.115	14.129	EPSD;PhosphoSitePlus	COSMIC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P41235	HNF4A	P27361	MAPK3	S167	P168T	168	Missense	proximal	1	no	14.115	5.237	EPSD;PhosphoSitePlus	COSMIC	9.358	Loss
CMGC_MAPK_ERK1_MAPK3_ST	P41235	HNF4A	P27361	MAPK3	S167	S170F	170	Missense	distal	3	no	14.115	14.050	EPSD;PhosphoSitePlus	COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P41235	HNF4A	P27361	MAPK3	S167	R163G	163	Missense	distal	-4	no	14.115	14.153	EPSD;PhosphoSitePlus	COSMIC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P41235	HNF4A	P27361	MAPK3	S167	R163Q	163	Missense	distal	-4	no	14.115	14.125	EPSD;PhosphoSitePlus	COSMIC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P41235	HNF4A	P27361	MAPK3	S167	G174D	174	Missense	distal	7	no	14.115	14.082	EPSD;PhosphoSitePlus	COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P41235	HNF4A	P27361	MAPK3	S318	L319P	319	Missense	proximal	1	no	7.385	16.423	EPSD	COSMIC	9.358	Gain
CMGC_MAPK_ERK1_MAPK3_ST	P41235	HNF4A	P27361	MAPK3	S378	M373V	373	Missense	distal	-5	no	16.130	16.173	EPSD	COSMIC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P41235	HNF4A	P27361	MAPK3	S378	H384Y	384	Missense	distal	6	no	16.130	15.971	EPSD	COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P41235	HNF4A	P27361	MAPK3	S378	E372K	372	Missense	distal	-6	no	16.130	15.989	EPSD	COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P41235	HNF4A	P27361	MAPK3	T429	A427D	427	Missense	proximal	-2	no	13.500	14.244	EPSD	COSMIC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P41235	HNF4A	P27361	MAPK3	T429	P433T	433	Missense	distal	4	no	13.500	13.436	EPSD	COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P41235	HNF4A	P27361	MAPK3	T429	G425E	425	Missense	distal	-4	no	13.500	13.514	EPSD	COSMIC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P41235	HNF4A	P27361	MAPK3	T429	P430S	430	Missense	proximal	1	no	13.500	4.446	EPSD	COSMIC	9.358	Loss
CMGC_MAPK_ERK1_MAPK3_ST	P41235	HNF4A	P27361	MAPK3	T429	A427T	427	Missense	proximal	-2	no	13.500	14.865	EPSD	COSMIC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P41235	HNF4A	P27361	MAPK3	T429	T429I	429	Missense	central	0	yes	13.500	0.000	EPSD	COSMIC	9.358	Loss
CMGC_MAPK_ERK1_MAPK3_ST	P41235	HNF4A	P27361	MAPK3	T429	P423T	423	Missense	distal	-6	no	13.500	13.416	EPSD	COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P41235	HNF4A	P27361	MAPK3	T432	A427D	427	Missense	distal	-5	no	17.272	17.337	EPSD	COSMIC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P41235	HNF4A	P27361	MAPK3	T432	P433T	433	Missense	proximal	1	no	17.272	8.395	EPSD	COSMIC	9.358	Loss
CMGC_MAPK_ERK1_MAPK3_ST	P41235	HNF4A	P27361	MAPK3	T432	G425E	425	Missense	distal	-7	no	17.272	17.267	EPSD	COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P41235	HNF4A	P27361	MAPK3	T432	P430S	430	Missense	proximal	-2	no	17.272	16.196	EPSD	COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P41235	HNF4A	P27361	MAPK3	T432	P437S	437	Missense	distal	5	no	17.272	17.315	EPSD	COSMIC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P41235	HNF4A	P27361	MAPK3	T432	A427T	427	Missense	distal	-5	no	17.272	17.356	EPSD	COSMIC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P41235	HNF4A	P27361	MAPK3	T432	T429I	429	Missense	distal	-3	no	17.272	17.191	EPSD	COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P41235	HNF4A	P27361	MAPK3	T432	G439C	439	Missense	distal	7	no	17.272	17.745	EPSD	COSMIC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P41235	HNF4A	P27361	MAPK3	T432	P437T	437	Missense	distal	5	no	17.272	17.180	EPSD	COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P41235	HNF4A	P27361	MAPK3	S436	P433T	433	Missense	distal	-3	no	15.690	15.652	EPSD	COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P41235	HNF4A	P27361	MAPK3	S436	P430S	430	Missense	distal	-6	no	15.690	15.775	EPSD	COSMIC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P41235	HNF4A	P27361	MAPK3	S436	P437S	437	Missense	proximal	1	no	15.690	6.637	EPSD	COSMIC	9.358	Loss
CMGC_MAPK_ERK1_MAPK3_ST	P41235	HNF4A	P27361	MAPK3	S436	T429I	429	Missense	distal	-7	no	15.690	15.805	EPSD	COSMIC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P41235	HNF4A	P27361	MAPK3	S436	G439C	439	Missense	distal	3	no	15.690	15.620	EPSD	COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P41235	HNF4A	P27361	MAPK3	S436	P437T	437	Missense	proximal	1	no	15.690	6.813	EPSD	COSMIC	9.358	Loss
CMGC_MAPK_ERK1_MAPK3_ST	P41235	HNF4A	P27361	MAPK3	T455	A452D	452	Missense	distal	-3	no	9.549	9.618	EPSD	COSMIC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P41235	HNF4A	P27361	MAPK3	T455	L460V	460	Missense	distal	5	no	9.549	9.553	EPSD	COSMIC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P41235	HNF4A	P27361	MAPK3	T455	P459T	459	Missense	distal	4	no	9.549	9.485	EPSD	COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P41235	HNF4A	P27361	MAPK3	T455	P459S	459	Missense	distal	4	no	9.549	9.598	EPSD	COSMIC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P41235	HNF4A	P27361	MAPK3	T455	P450L	450	Missense	distal	-5	no	9.549	9.494	EPSD	COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P41235	HNF4A	P27361	MAPK3	T455	A454T	454	Missense	proximal	-1	no	9.549	9.652	EPSD	COSMIC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P41235	HNF4A	P27361	MAPK3	S461	L460V	460	Missense	proximal	-1	no	10.418	10.423	EPSD;PhosphoSitePlus	COSMIC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P41235	HNF4A	P27361	MAPK3	S461	P459T	459	Missense	proximal	-2	no	10.418	9.432	EPSD;PhosphoSitePlus	COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P41235	HNF4A	P27361	MAPK3	S461	P459S	459	Missense	proximal	-2	no	10.418	9.342	EPSD;PhosphoSitePlus	COSMIC	9.358	Loss
CMGC_MAPK_ERK1_MAPK3_ST	P41235	HNF4A	P27361	MAPK3	S461	A454T	454	Missense	distal	-7	no	10.418	10.345	EPSD;PhosphoSitePlus	COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q9NYV6	RRN3	P27361	MAPK3	S172	D171E	171	Missense	proximal	-1	no	10.486	10.508	EPSD	COSMIC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q9NYV6	RRN3	P27361	MAPK3	S409	G404E	404	Missense	distal	-5	no	10.269	10.278	EPSD	COSMIC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q9NYV6	RRN3	P27361	MAPK3	S409	S409P	409	Missense	central	0	yes	10.269	0.000	EPSD	COSMIC	9.358	Loss
CMGC_MAPK_ERK1_MAPK3_ST	Q9NYV6	RRN3	P27361	MAPK3	T623	P624L	624	Missense	proximal	1	no	16.050	7.012	EPSD	COSMIC	9.358	Loss
CMGC_MAPK_ERK1_MAPK3_ST	Q9NYV6	RRN3	P27361	MAPK3	T623	N616S	616	Missense	distal	-7	no	16.050	15.982	EPSD	COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q9NYV6	RRN3	P27361	MAPK3	T623	T629M	629	Missense	distal	6	no	16.050	15.556	EPSD	COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q9NYV6	RRN3	P27361	MAPK3	T623	T618I	618	Missense	distal	-5	no	16.050	15.971	EPSD	COSMIC;CCLE	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q9NYV6	RRN3	P27361	MAPK3	S625	P624L	624	Missense	proximal	-1	no	9.466	9.372	EPSD	COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q9NYV6	RRN3	P27361	MAPK3	S625	T629M	629	Missense	distal	4	no	9.466	9.201	EPSD	COSMIC	9.358	Loss
CMGC_MAPK_ERK1_MAPK3_ST	Q9NYV6	RRN3	P27361	MAPK3	S625	T618I	618	Missense	distal	-7	no	9.466	9.581	EPSD	COSMIC;CCLE	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q9NYV6	RRN3	P27361	MAPK3	S626	P624L	624	Missense	proximal	-2	no	12.891	11.507	EPSD	COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q9NYV6	RRN3	P27361	MAPK3	S626	T629M	629	Missense	distal	3	no	12.891	12.843	EPSD	COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q9NYV6	RRN3	P27361	MAPK3	S633	T629M	629	Missense	distal	-4	no	18.912	18.791	PhosphoSitePlus	COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q9NYV6	RRN3	P27361	MAPK3	S635	T629M	629	Missense	distal	-6	no	10.745	10.492	EPSD	COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q9NYV6	RRN3	P27361	MAPK3	S636	T629M	629	Missense	distal	-7	no	11.145	11.274	EPSD	COSMIC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q9NYV6	RRN3	P27361	MAPK3	S649	P650S	650	Missense	proximal	1	no	20.025	10.972	EPSD	COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q9NYV6	RRN3	P27361	MAPK3	S649	P650L	650	Missense	proximal	1	no	20.025	10.987	EPSD	COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q9NYV6	RRN3	P27361	MAPK3	S649	P648H	648	Missense	proximal	-1	no	20.025	19.980	EPSD	COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P07101	TH	P27361	MAPK3	T3	A6T	6	Missense	distal	3	no	12.306	12.336	EPSD	COSMIC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P07101	TH	P27361	MAPK3	T3	A6P	6	Missense	distal	3	no	12.306	12.354	EPSD	COSMIC;GDSC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P07101	TH	P27361	MAPK3	T8	R15S	15	Missense	distal	7	no	13.260	13.091	EPSD	COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P07101	TH	P27361	MAPK3	T8	A6T	6	Missense	proximal	-2	no	13.260	14.625	EPSD	COSMIC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P07101	TH	P27361	MAPK3	T8	A6P	6	Missense	proximal	-2	no	13.260	15.611	EPSD	COSMIC;GDSC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P07101	TH	P27361	MAPK3	S62	R64Q	64	Missense	proximal	2	no	17.063	17.053	EPSD;PhosphoSitePlus	COSMIC;CCLE	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P07101	TH	P27361	MAPK3	S118	V112M	112	Missense	distal	-6	no	17.120	17.027	EPSD	COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P07101	TH	P27361	MAPK3	S118	R120S	120	Missense	proximal	2	no	17.120	17.132	EPSD	COSMIC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P07101	TH	P27361	MAPK3	S502	S509F	509	Missense	distal	7	no	17.074	17.565	EPSD	COSMIC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P07101	TH	P27361	MAPK3	S502	V506M	506	Missense	distal	4	no	17.074	16.919	EPSD	COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P07101	TH	P27361	MAPK3	S502	P503H	503	Missense	proximal	1	no	17.074	9.318	EPSD	COSMIC	9.358	Loss
CMGC_MAPK_ERK1_MAPK3_ST	P49790	NUP153	P27361	MAPK3	T102	T97A	97	Missense	distal	-5	no	13.795	13.712	EPSD	COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P49790	NUP153	P27361	MAPK3	S174	H176R	176	Missense	proximal	2	no	10.339	10.342	EPSD	COSMIC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P49790	NUP153	P27361	MAPK3	S174	I181L	181	Missense	distal	7	no	10.339	10.211	EPSD	COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P49790	NUP153	P27361	MAPK3	S174	D171N	171	Missense	distal	-3	no	10.339	10.318	EPSD	COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P49790	NUP153	P27361	MAPK3	S174	Q175R	175	Missense	proximal	1	no	10.339	8.783	EPSD	COSMIC	9.358	Loss
CMGC_MAPK_ERK1_MAPK3_ST	P49790	NUP153	P27361	MAPK3	S240	G237V	237	Missense	distal	-3	no	16.590	16.550	EPSD	COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P49790	NUP153	P27361	MAPK3	S257	F259L	259	Missense	proximal	2	no	15.553	15.580	EPSD;PhosphoSitePlus	COSMIC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P49790	NUP153	P27361	MAPK3	S257	Y260N	260	Missense	distal	3	no	15.553	15.563	EPSD;PhosphoSitePlus	COSMIC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P49790	NUP153	P27361	MAPK3	T281	R279Q	279	Missense	proximal	-2	no	13.963	13.599	EPSD	COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P49790	NUP153	P27361	MAPK3	S320	M318I	318	Missense	proximal	-2	no	17.303	18.219	EPSD;PhosphoSitePlus	COSMIC;GDSC;CCLE	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P49790	NUP153	P27361	MAPK3	S320	A325G	325	Missense	distal	5	no	17.303	17.494	EPSD;PhosphoSitePlus	COSMIC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P49790	NUP153	P27361	MAPK3	S320	A323V	323	Missense	distal	3	no	17.303	17.309	EPSD;PhosphoSitePlus	COSMIC;GDSC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P49790	NUP153	P27361	MAPK3	S320	M318T	318	Missense	proximal	-2	no	17.303	19.071	EPSD;PhosphoSitePlus	COSMIC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P49790	NUP153	P27361	MAPK3	S334	S333P	333	Missense	proximal	-1	no	14.207	14.213	EPSD;PhosphoSitePlus	COSMIC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P49790	NUP153	P27361	MAPK3	S334	P335L	335	Missense	proximal	1	no	14.207	5.169	EPSD;PhosphoSitePlus	COSMIC	9.358	Loss
CMGC_MAPK_ERK1_MAPK3_ST	P49790	NUP153	P27361	MAPK3	S334	V332F	332	Missense	proximal	-2	no	14.207	13.485	EPSD;PhosphoSitePlus	COSMIC;GDSC;CCLE	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P49790	NUP153	P27361	MAPK3	S338	S333P	333	Missense	distal	-5	no	16.571	16.566	EPSD;PhosphoSitePlus	COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P49790	NUP153	P27361	MAPK3	S338	P335L	335	Missense	distal	-3	no	16.571	16.487	EPSD;PhosphoSitePlus	COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P49790	NUP153	P27361	MAPK3	S338	V332F	332	Missense	distal	-6	no	16.571	16.433	EPSD;PhosphoSitePlus	COSMIC;GDSC;CCLE	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P49790	NUP153	P27361	MAPK3	T413	G415R	415	Missense	proximal	2	no	14.096	14.101	EPSD;PhosphoSitePlus	COSMIC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P49790	NUP153	P27361	MAPK3	T486	P485L	485	Missense	proximal	-1	no	10.174	10.079	EPSD	COSMIC;GDSC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P49790	NUP153	P27361	MAPK3	S491	P485L	485	Missense	distal	-6	no	15.623	15.376	EPSD	COSMIC;GDSC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P49790	NUP153	P27361	MAPK3	S516	S518R	518	Missense	proximal	2	no	17.006	16.993	PhosphoSitePlus;EPSD	COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P49790	NUP153	P27361	MAPK3	S516	P517S	517	Missense	proximal	1	no	17.006	7.952	PhosphoSitePlus;EPSD	COSMIC	9.358	Loss
CMGC_MAPK_ERK1_MAPK3_ST	P49790	NUP153	P27361	MAPK3	S516	P523S	523	Missense	distal	7	no	17.006	16.928	PhosphoSitePlus;EPSD	COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P49790	NUP153	P27361	MAPK3	S516	S522F	522	Missense	distal	6	no	17.006	16.292	PhosphoSitePlus;EPSD	COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P49790	NUP153	P27361	MAPK3	S522	S518R	518	Missense	distal	-4	no	16.518	16.441	EPSD;PhosphoSitePlus	COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P49790	NUP153	P27361	MAPK3	S522	P517S	517	Missense	distal	-5	no	16.518	16.523	EPSD;PhosphoSitePlus	COSMIC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P49790	NUP153	P27361	MAPK3	S522	P523S	523	Missense	proximal	1	no	16.518	7.465	EPSD;PhosphoSitePlus	COSMIC	9.358	Loss
CMGC_MAPK_ERK1_MAPK3_ST	P49790	NUP153	P27361	MAPK3	S522	S522F	522	Missense	central	0	yes	16.518	0.000	EPSD;PhosphoSitePlus	COSMIC	9.358	Loss
CMGC_MAPK_ERK1_MAPK3_ST	P49790	NUP153	P27361	MAPK3	S529	P523S	523	Missense	distal	-6	no	15.387	15.472	EPSD;PhosphoSitePlus	COSMIC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P49790	NUP153	P27361	MAPK3	S529	T535I	535	Missense	distal	6	no	15.387	14.973	EPSD;PhosphoSitePlus	COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P49790	NUP153	P27361	MAPK3	S529	S522F	522	Missense	distal	-7	no	15.387	15.607	EPSD;PhosphoSitePlus	COSMIC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P49790	NUP153	P27361	MAPK3	S573	I569V	569	Missense	distal	-4	no	9.772	9.779	EPSD	COSMIC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P49790	NUP153	P27361	MAPK3	T588	P589S	589	Missense	proximal	1	no	14.960	5.907	EPSD	COSMIC;GDSC	9.358	Loss
CMGC_MAPK_ERK1_MAPK3_ST	P49790	NUP153	P27361	MAPK3	S614	P620S	620	Missense	distal	6	no	15.797	15.926	EPSD	COSMIC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P49790	NUP153	P27361	MAPK3	S619	P620S	620	Missense	proximal	1	no	14.573	5.519	EPSD	COSMIC	9.358	Loss
CMGC_MAPK_ERK1_MAPK3_ST	P49790	NUP153	P27361	MAPK3	S633	A631S	631	Missense	proximal	-2	no	15.589	16.864	EPSD	COSMIC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P49790	NUP153	P27361	MAPK3	S687	T691I	691	Missense	distal	4	no	13.863	13.635	EPSD	COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P49790	NUP153	P27361	MAPK3	S687	Q694H	694	Missense	distal	7	no	13.863	13.801	EPSD	COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P49790	NUP153	P27361	MAPK3	S687	S687P	687	Missense	central	0	yes	13.863	0.000	EPSD	COSMIC	9.358	Loss
CMGC_MAPK_ERK1_MAPK3_ST	P49790	NUP153	P27361	MAPK3	T699	Q694H	694	Missense	distal	-5	no	15.269	15.285	EPSD	COSMIC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P49790	NUP153	P27361	MAPK3	S711	G712W	712	Missense	proximal	1	no	6.625	10.260	EPSD	COSMIC	9.358	Gain
CMGC_MAPK_ERK1_MAPK3_ST	P49790	NUP153	P27361	MAPK3	T747	V743A	743	Missense	distal	-4	no	13.833	13.853	EPSD	COSMIC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P49790	NUP153	P27361	MAPK3	S902	S895L	895	Missense	distal	-7	no	13.463	13.608	EPSD	COSMIC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P49790	NUP153	P27361	MAPK3	S902	S902Y	902	Missense	central	0	yes	13.463	0.000	EPSD	COSMIC	9.358	Loss
CMGC_MAPK_ERK1_MAPK3_ST	P49790	NUP153	P27361	MAPK3	S902	K904I	904	Missense	proximal	2	no	13.463	13.444	EPSD	COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P49790	NUP153	P27361	MAPK3	S902	S900Y	900	Missense	proximal	-2	no	13.463	13.230	EPSD	COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P49790	NUP153	P27361	MAPK3	T996	V1002A	1002	Missense	distal	6	no	13.637	13.550	EPSD	COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P49790	NUP153	P27361	MAPK3	T996	T996I	996	Missense	central	0	yes	13.637	0.000	EPSD	COSMIC	9.358	Loss
CMGC_MAPK_ERK1_MAPK3_ST	P49790	NUP153	P27361	MAPK3	S1017	S1018F	1018	Missense	proximal	1	no	9.246	12.086	EPSD	COSMIC	9.358	Gain
CMGC_MAPK_ERK1_MAPK3_ST	P49790	NUP153	P27361	MAPK3	T1032	A1036P	1036	Missense	distal	4	no	14.509	14.791	EPSD	COSMIC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P49790	NUP153	P27361	MAPK3	T1032	P1035S	1035	Missense	distal	3	no	14.509	14.504	EPSD	COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P49790	NUP153	P27361	MAPK3	T1114	S1115F	1115	Missense	proximal	1	no	7.000	9.840	EPSD	COSMIC	9.358	Gain
CMGC_MAPK_ERK1_MAPK3_ST	P49790	NUP153	P27361	MAPK3	S1152	S1146F	1146	Missense	distal	-6	no	10.188	9.721	EPSD	COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P49790	NUP153	P27361	MAPK3	S1456	V1454M	1454	Missense	proximal	-2	no	9.519	8.419	EPSD	COSMIC;GDSC;CCLE	9.358	Loss
CMGC_MAPK_ERK1_MAPK3_ST	P49790	NUP153	P27361	MAPK3	S1457	V1454M	1454	Missense	distal	-3	no	9.644	9.589	EPSD	COSMIC;GDSC;CCLE	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P49790	NUP153	P27361	MAPK3	S1461	V1454M	1454	Missense	distal	-7	no	11.219	11.274	EPSD	COSMIC;GDSC;CCLE	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P49790	NUP153	P27361	MAPK3	S1461	I1467M	1467	Missense	distal	6	no	11.219	11.139	EPSD	COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P04049	RAF1	P27361	MAPK3	S25	F22L	22	Missense	distal	-3	no	10.015	10.081	EPSD	COSMIC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P04049	RAF1	P27361	MAPK3	S29	V33L	33	Missense	distal	4	no	15.915	15.935	EPSD	COSMIC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P04049	RAF1	P27361	MAPK3	S29	F22L	22	Missense	distal	-7	no	15.915	15.841	EPSD	COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P04049	RAF1	P27361	MAPK3	T234	A237T	237	Missense	distal	3	no	14.194	14.224	EPSD	COSMIC;CCLE	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P04049	RAF1	P27361	MAPK3	S244	A237T	237	Missense	distal	-7	no	16.383	16.309	EPSD	COSMIC;CCLE	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P04049	RAF1	P27361	MAPK3	S244	L251V	251	Missense	distal	7	no	16.383	16.431	EPSD	COSMIC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P04049	RAF1	P27361	MAPK3	S244	S244R	244	Missense	central	0	yes	16.383	0.000	EPSD	COSMIC	9.358	Loss
CMGC_MAPK_ERK1_MAPK3_ST	P04049	RAF1	P27361	MAPK3	T258	S259P	259	Missense	proximal	1	no	6.027	15.080	EPSD	COSMIC	9.358	Gain
CMGC_MAPK_ERK1_MAPK3_ST	P04049	RAF1	P27361	MAPK3	T260	S259A	259	Missense	proximal	-1	no	13.506	13.373	EPSD	COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P04049	RAF1	P27361	MAPK3	T260	P261L	261	Missense	proximal	1	no	13.506	4.468	EPSD	COSMIC	9.358	Loss
CMGC_MAPK_ERK1_MAPK3_ST	P04049	RAF1	P27361	MAPK3	T260	S259C	259	Missense	proximal	-1	no	13.506	13.280	EPSD	COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P04049	RAF1	P27361	MAPK3	T260	S259P	259	Missense	proximal	-1	no	13.506	13.512	EPSD	COSMIC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P04049	RAF1	P27361	MAPK3	T260	T260K	260	Missense	central	0	yes	13.506	0.000	EPSD	COSMIC	9.358	Loss
CMGC_MAPK_ERK1_MAPK3_ST	P04049	RAF1	P27361	MAPK3	T260	P261T	261	Missense	proximal	1	no	13.506	4.629	EPSD	COSMIC	9.358	Loss
CMGC_MAPK_ERK1_MAPK3_ST	P04049	RAF1	P27361	MAPK3	T260	N262K	262	Missense	proximal	2	no	13.506	13.508	EPSD	COSMIC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P04049	RAF1	P27361	MAPK3	T260	T260I	260	Missense	central	0	yes	13.506	0.000	EPSD	COSMIC	9.358	Loss
CMGC_MAPK_ERK1_MAPK3_ST	P04049	RAF1	P27361	MAPK3	T260	P261S	261	Missense	proximal	1	no	13.506	4.453	EPSD	COSMIC	9.358	Loss
CMGC_MAPK_ERK1_MAPK3_ST	P04049	RAF1	P27361	MAPK3	T260	V263A	263	Missense	distal	3	no	13.506	13.500	EPSD	COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P04049	RAF1	P27361	MAPK3	T260	V263D	263	Missense	distal	3	no	13.506	13.533	EPSD	COSMIC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P04049	RAF1	P27361	MAPK3	S283	I277N	277	Missense	distal	-6	no	9.633	9.909	EPSD	COSMIC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P04049	RAF1	P27361	MAPK3	S283	R282Q	282	Missense	proximal	-1	no	9.633	9.594	EPSD	COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P04049	RAF1	P27361	MAPK3	S283	S289L	289	Missense	distal	6	no	9.633	9.277	EPSD	COSMIC	9.358	Loss
CMGC_MAPK_ERK1_MAPK3_ST	P04049	RAF1	P27361	MAPK3	S283	S285F	285	Missense	proximal	2	no	9.633	9.583	EPSD	COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P04049	RAF1	P27361	MAPK3	S289	S295G	295	Missense	distal	6	no	16.543	16.311	PhosphoSitePlus;EPSD	COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P04049	RAF1	P27361	MAPK3	S289	R282Q	282	Missense	distal	-7	no	16.543	16.542	PhosphoSitePlus;EPSD	COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P04049	RAF1	P27361	MAPK3	S289	S295C	295	Missense	distal	6	no	16.543	15.676	PhosphoSitePlus;EPSD	COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P04049	RAF1	P27361	MAPK3	S289	S289L	289	Missense	central	0	yes	16.543	0.000	PhosphoSitePlus;EPSD	COSMIC	9.358	Loss
CMGC_MAPK_ERK1_MAPK3_ST	P04049	RAF1	P27361	MAPK3	S289	S291L	291	Missense	proximal	2	no	16.543	16.520	PhosphoSitePlus;EPSD	COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P04049	RAF1	P27361	MAPK3	S289	S285F	285	Missense	distal	-4	no	16.543	16.354	PhosphoSitePlus;EPSD	COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P04049	RAF1	P27361	MAPK3	S296	S295G	295	Missense	proximal	-1	no	17.053	16.988	EPSD;PhosphoSitePlus	COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P04049	RAF1	P27361	MAPK3	S296	S301R	301	Missense	distal	5	no	17.053	16.910	EPSD;PhosphoSitePlus	COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P04049	RAF1	P27361	MAPK3	S296	S295C	295	Missense	proximal	-1	no	17.053	16.827	EPSD;PhosphoSitePlus	COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P04049	RAF1	P27361	MAPK3	S296	S289L	289	Missense	distal	-7	no	17.053	17.198	EPSD;PhosphoSitePlus	COSMIC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P04049	RAF1	P27361	MAPK3	S296	S291L	291	Missense	distal	-5	no	17.053	16.994	EPSD;PhosphoSitePlus	COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P04049	RAF1	P27361	MAPK3	S301	S295G	295	Missense	distal	-6	no	15.772	15.710	EPSD;PhosphoSitePlus	COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P04049	RAF1	P27361	MAPK3	S301	S301R	301	Missense	central	0	yes	15.772	0.000	EPSD;PhosphoSitePlus	COSMIC	9.358	Loss
CMGC_MAPK_ERK1_MAPK3_ST	P04049	RAF1	P27361	MAPK3	S301	S295C	295	Missense	distal	-6	no	15.772	15.213	EPSD;PhosphoSitePlus	COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P04049	RAF1	P27361	MAPK3	S306	V312E	312	Missense	distal	6	no	9.232	9.539	EPSD	COSMIC	9.358	Gain
CMGC_MAPK_ERK1_MAPK3_ST	P04049	RAF1	P27361	MAPK3	T310	V312E	312	Missense	proximal	2	no	17.122	17.138	EPSD	COSMIC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P04049	RAF1	P27361	MAPK3	S339	R333C	333	Missense	distal	-6	no	10.322	9.924	EPSD	COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P04049	RAF1	P27361	MAPK3	S339	Q335H	335	Missense	distal	-4	no	10.322	10.326	EPSD	COSMIC;GDSC;CCLE	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P04049	RAF1	P27361	MAPK3	S359	G361A	361	Missense	proximal	2	no	9.764	9.742	EPSD	COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P04049	RAF1	P27361	MAPK3	S359	S359C	359	Missense	central	0	yes	9.764	0.000	EPSD	COSMIC	9.358	Loss
CMGC_MAPK_ERK1_MAPK3_ST	P04049	RAF1	P27361	MAPK3	S359	G361R	361	Missense	proximal	2	no	9.764	9.768	EPSD	COSMIC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P04049	RAF1	P27361	MAPK3	S359	K365R	365	Missense	distal	6	no	9.764	9.730	EPSD	COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P04049	RAF1	P27361	MAPK3	S359	G366D	366	Missense	distal	7	no	9.764	9.731	EPSD	COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P04049	RAF1	P27361	MAPK3	S494	R495H	495	Missense	proximal	1	no	8.109	9.854	EPSD	COSMIC;GDSC;CCLE	9.358	Gain
CMGC_MAPK_ERK1_MAPK3_ST	P04049	RAF1	P27361	MAPK3	S642	P643S	643	Missense	proximal	1	no	20.254	11.201	EPSD	COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q16690	DUSP5	P27361	MAPK3	S346	P347S	347	Missense	proximal	1	no	16.493	7.439	EPSD;PhosphoSitePlus	COSMIC	9.358	Loss
CMGC_MAPK_ERK1_MAPK3_ST	P15336	ATF2	P27361	MAPK3	T69	T73A	73	Missense	distal	4	no	14.813	14.595	PhosphoSitePlus;EPSD	COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P15336	ATF2	P27361	MAPK3	T69	F75L	75	Missense	distal	6	no	14.813	15.170	PhosphoSitePlus;EPSD	COSMIC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P15336	ATF2	P27361	MAPK3	T69	R74T	74	Missense	distal	5	no	14.813	14.821	PhosphoSitePlus;EPSD	COSMIC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P15336	ATF2	P27361	MAPK3	T69	I64V	64	Missense	distal	-5	no	14.813	14.832	PhosphoSitePlus;EPSD	COSMIC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P15336	ATF2	P27361	MAPK3	T69	D67E	67	Missense	proximal	-2	no	14.813	14.774	PhosphoSitePlus;EPSD	COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P15336	ATF2	P27361	MAPK3	T71	T73A	73	Missense	proximal	2	no	14.842	14.815	EPSD;PhosphoSitePlus	COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P15336	ATF2	P27361	MAPK3	T71	F75L	75	Missense	distal	4	no	14.842	15.053	EPSD;PhosphoSitePlus	COSMIC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P15336	ATF2	P27361	MAPK3	T71	R74T	74	Missense	distal	3	no	14.842	14.851	EPSD;PhosphoSitePlus	COSMIC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P15336	ATF2	P27361	MAPK3	T71	I64V	64	Missense	distal	-7	no	14.842	14.800	EPSD;PhosphoSitePlus	COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P15336	ATF2	P27361	MAPK3	T71	D67E	67	Missense	distal	-4	no	14.842	14.853	EPSD;PhosphoSitePlus	COSMIC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P15336	ATF2	P27361	MAPK3	S90	P91S	91	Missense	proximal	1	no	15.922	6.868	EPSD	COSMIC	9.358	Loss
CMGC_MAPK_ERK1_MAPK3_ST	P15336	ATF2	P27361	MAPK3	S90	A89V	89	Missense	proximal	-1	no	15.922	15.971	EPSD	COSMIC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P15336	ATF2	P27361	MAPK3	S90	P91L	91	Missense	proximal	1	no	15.922	6.884	EPSD	COSMIC	9.358	Loss
CMGC_MAPK_ERK1_MAPK3_ST	P15336	ATF2	P27361	MAPK3	S90	G83C	83	Missense	distal	-7	no	15.922	16.154	EPSD	COSMIC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P15336	ATF2	P27361	MAPK3	S112	M107I	107	Missense	distal	-5	no	15.741	15.765	EPSD	COSMIC;GDSC;CCLE	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P15336	ATF2	P27361	MAPK3	S112	K105T	105	Missense	distal	-7	no	15.741	15.734	EPSD	COSMIC;GDSC;CCLE	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P15336	ATF2	P27361	MAPK3	S112	K106R	106	Missense	distal	-6	no	15.741	15.739	EPSD	COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P15336	ATF2	P27361	MAPK3	S112	D110E	110	Missense	proximal	-2	no	15.741	15.702	EPSD	COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P15336	ATF2	P27361	MAPK3	T116	D110E	110	Missense	distal	-6	no	14.801	14.846	EPSD	COSMIC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P15336	ATF2	P27361	MAPK3	S136	P141T	141	Missense	distal	5	no	16.279	16.187	EPSD	COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P15336	ATF2	P27361	MAPK3	S136	P141L	141	Missense	distal	5	no	16.279	16.052	EPSD	COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P15336	ATF2	P27361	MAPK3	S136	P137S	137	Missense	proximal	1	no	16.279	7.226	EPSD	COSMIC	9.358	Loss
CMGC_MAPK_ERK1_MAPK3_ST	P15336	ATF2	P27361	MAPK3	S143	P141T	141	Missense	proximal	-2	no	10.251	9.265	EPSD	COSMIC	9.358	Loss
CMGC_MAPK_ERK1_MAPK3_ST	P15336	ATF2	P27361	MAPK3	S143	P141L	141	Missense	proximal	-2	no	10.251	8.866	EPSD	COSMIC	9.358	Loss
CMGC_MAPK_ERK1_MAPK3_ST	P15336	ATF2	P27361	MAPK3	S143	D147Y	147	Missense	distal	4	no	10.251	10.154	EPSD	COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P15336	ATF2	P27361	MAPK3	S143	P137S	137	Missense	distal	-6	no	10.251	10.335	EPSD	COSMIC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P15336	ATF2	P27361	MAPK3	S143	T144I	144	Missense	proximal	1	no	10.251	9.620	EPSD	COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P15336	ATF2	P27361	MAPK3	S146	D147Y	147	Missense	proximal	1	no	8.905	10.458	EPSD	COSMIC	9.358	Gain
CMGC_MAPK_ERK1_MAPK3_ST	P15336	ATF2	P27361	MAPK3	S265	S266P	266	Missense	proximal	1	no	5.843	14.896	EPSD	COSMIC	9.358	Gain
CMGC_MAPK_ERK1_MAPK3_ST	P15336	ATF2	P27361	MAPK3	S266	S266P	266	Missense	central	0	yes	17.433	0.000	EPSD	COSMIC	9.358	Loss
CMGC_MAPK_ERK1_MAPK3_ST	P15336	ATF2	P27361	MAPK3	S266	P269Q	269	Missense	distal	3	no	17.433	17.407	EPSD	COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P15336	ATF2	P27361	MAPK3	S266	S265F	265	Missense	proximal	-1	no	17.433	17.229	EPSD	COSMIC;GDSC;CCLE	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P15336	ATF2	P27361	MAPK3	S266	P269S	269	Missense	distal	3	no	17.433	17.429	EPSD	COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P15336	ATF2	P27361	MAPK3	T325	P326L	326	Missense	proximal	1	no	14.306	5.268	EPSD	COSMIC;GDSC	9.358	Loss
CMGC_MAPK_ERK1_MAPK3_ST	P15336	ATF2	P27361	MAPK3	T325	P326T	326	Missense	proximal	1	no	14.306	5.429	EPSD	COSMIC	9.358	Loss
CMGC_MAPK_ERK1_MAPK3_ST	P15336	ATF2	P27361	MAPK3	T325	H331Y	331	Missense	distal	6	no	14.306	14.146	EPSD	COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P15336	ATF2	P27361	MAPK3	S328	P326L	326	Missense	proximal	-2	no	17.676	16.292	EPSD	COSMIC;GDSC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P15336	ATF2	P27361	MAPK3	S328	P326T	326	Missense	proximal	-2	no	17.676	16.690	EPSD	COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P15336	ATF2	P27361	MAPK3	S328	Q335H	335	Missense	distal	7	no	17.676	17.614	EPSD	COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P15336	ATF2	P27361	MAPK3	S328	P334S	334	Missense	distal	6	no	17.676	17.806	EPSD	COSMIC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P15336	ATF2	P27361	MAPK3	S328	H331Y	331	Missense	distal	3	no	17.676	17.660	EPSD	COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P15336	ATF2	P27361	MAPK3	T333	Q337K	337	Missense	distal	4	no	15.687	15.739	EPSD	COSMIC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P15336	ATF2	P27361	MAPK3	T333	P326L	326	Missense	distal	-7	no	15.687	15.794	EPSD	COSMIC;GDSC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P15336	ATF2	P27361	MAPK3	T333	P326T	326	Missense	distal	-7	no	15.687	15.726	EPSD	COSMIC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P15336	ATF2	P27361	MAPK3	T333	Q335H	335	Missense	proximal	2	no	15.687	15.693	EPSD	COSMIC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P15336	ATF2	P27361	MAPK3	T333	P334S	334	Missense	proximal	1	no	15.687	6.633	EPSD	COSMIC	9.358	Loss
CMGC_MAPK_ERK1_MAPK3_ST	P15336	ATF2	P27361	MAPK3	T333	H331Y	331	Missense	proximal	-2	no	15.687	15.605	EPSD	COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P15336	ATF2	P27361	MAPK3	S446	S442L	442	Missense	distal	-4	no	17.263	17.123	EPSD	COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P15336	ATF2	P27361	MAPK3	S446	P444L	444	Missense	proximal	-2	no	17.263	15.879	EPSD	COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P15336	ATF2	P27361	MAPK3	S446	P444T	444	Missense	proximal	-2	no	17.263	16.277	EPSD	COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P15336	ATF2	P27361	MAPK3	S446	S442P	442	Missense	distal	-4	no	17.263	17.236	EPSD	COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P15336	ATF2	P27361	MAPK3	S446	P444Q	444	Missense	proximal	-2	no	17.263	15.499	EPSD	COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P15336	ATF2	P27361	MAPK3	S497	V493I	493	Missense	distal	-4	no	9.495	9.488	EPSD	COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P15336	ATF2	P27361	MAPK3	S497	Q501K	501	Missense	distal	4	no	9.495	9.548	EPSD	COSMIC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P15336	ATF2	P27361	MAPK3	S498	V493I	493	Missense	distal	-5	no	12.964	12.945	EPSD	COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P15336	ATF2	P27361	MAPK3	S498	Q501K	501	Missense	distal	3	no	12.964	12.962	EPSD	COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P15336	ATF2	P27361	MAPK3	S500	V493I	493	Missense	distal	-7	no	12.203	12.245	EPSD	COSMIC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P15336	ATF2	P27361	MAPK3	S500	Q501K	501	Missense	proximal	1	no	12.203	2.994	EPSD	COSMIC	9.358	Loss
CMGC_MAPK_ERK1_MAPK3_ST	P49023	PXN	P27361	MAPK3	T29	P22L	22	Missense	distal	-7	no	16.399	16.506	EPSD	COSMIC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P49023	PXN	P27361	MAPK3	T29	P22H	22	Missense	distal	-7	no	16.399	16.433	EPSD	COSMIC;GDSC;CCLE	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P49023	PXN	P27361	MAPK3	T29	P30L	30	Missense	proximal	1	no	16.399	7.361	EPSD	COSMIC	9.358	Loss
CMGC_MAPK_ERK1_MAPK3_ST	P49023	PXN	P27361	MAPK3	S32	P30L	30	Missense	proximal	-2	no	10.893	9.509	EPSD	COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P49023	PXN	P27361	MAPK3	S85	S83N	83	Missense	proximal	-2	no	15.864	14.920	EPSD	COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P49023	PXN	P27361	MAPK3	S106	P107L	107	Missense	proximal	1	no	16.832	7.794	EPSD	COSMIC;GDSC	9.358	Loss
CMGC_MAPK_ERK1_MAPK3_ST	P49023	PXN	P27361	MAPK3	S106	P107Q	107	Missense	proximal	1	no	16.832	8.888	EPSD	COSMIC	9.358	Loss
CMGC_MAPK_ERK1_MAPK3_ST	P49023	PXN	P27361	MAPK3	S119	F120S	120	Missense	proximal	1	no	10.827	7.987	EPSD	COSMIC	9.358	Loss
CMGC_MAPK_ERK1_MAPK3_ST	P49023	PXN	P27361	MAPK3	S119	S126P	126	Missense	distal	7	no	10.827	10.904	EPSD	COSMIC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P49023	PXN	P27361	MAPK3	S130	V133I	133	Missense	distal	3	no	15.799	15.785	EPSD;PhosphoSitePlus	COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P49023	PXN	P27361	MAPK3	S130	A127T	127	Missense	distal	-3	no	15.799	15.860	EPSD;PhosphoSitePlus	COSMIC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P49023	PXN	P27361	MAPK3	S130	T136M	136	Missense	distal	6	no	15.799	15.304	EPSD;PhosphoSitePlus	COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P49023	PXN	P27361	MAPK3	S130	S126P	126	Missense	distal	-4	no	15.799	15.771	EPSD;PhosphoSitePlus	COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P49023	PXN	P27361	MAPK3	S170	D165Y	165	Missense	distal	-5	no	15.357	15.328	EPSD	COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P49023	PXN	P27361	MAPK3	S170	G175W	175	Missense	distal	5	no	15.357	14.810	EPSD	COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P49023	PXN	P27361	MAPK3	S170	P163L	163	Missense	distal	-7	no	15.357	15.464	EPSD	COSMIC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P49023	PXN	P27361	MAPK3	S170	P172L	172	Missense	proximal	2	no	15.357	15.335	EPSD	COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P49023	PXN	P27361	MAPK3	S170	P171S	171	Missense	proximal	1	no	15.357	6.303	EPSD	COSMIC	9.358	Loss
CMGC_MAPK_ERK1_MAPK3_ST	P49023	PXN	P27361	MAPK3	S170	N168I	168	Missense	proximal	-2	no	15.357	15.539	EPSD	COSMIC;GDSC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P49023	PXN	P27361	MAPK3	S178	G175W	175	Missense	distal	-3	no	15.251	15.079	EPSD	COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P49023	PXN	P27361	MAPK3	S178	P172L	172	Missense	distal	-6	no	15.251	15.004	EPSD	COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P49023	PXN	P27361	MAPK3	S178	P171S	171	Missense	distal	-7	no	15.251	15.214	EPSD	COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P49023	PXN	P27361	MAPK3	S230	P231L	231	Missense	proximal	1	no	14.654	5.616	EPSD	COSMIC;CCLE	9.358	Loss
CMGC_MAPK_ERK1_MAPK3_ST	P49023	PXN	P27361	MAPK3	S230	P229L	229	Missense	proximal	-1	no	14.654	14.559	EPSD	COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P49023	PXN	P27361	MAPK3	S244	E241D	241	Missense	distal	-3	no	12.682	12.679	EPSD	COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P49023	PXN	P27361	MAPK3	S303	P304L	304	Missense	proximal	1	no	16.789	7.751	EPSD	COSMIC	9.358	Loss
CMGC_MAPK_ERK1_MAPK3_ST	P49023	PXN	P27361	MAPK3	S303	P304R	304	Missense	proximal	1	no	16.789	7.288	EPSD	COSMIC	9.358	Loss
CMGC_MAPK_ERK1_MAPK3_ST	P49023	PXN	P27361	MAPK3	S303	G300R	300	Missense	distal	-3	no	16.789	16.784	EPSD	COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P49023	PXN	P27361	MAPK3	S303	E309K	309	Missense	distal	6	no	16.789	16.713	EPSD	COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P49023	PXN	P27361	MAPK3	S303	D298Y	298	Missense	distal	-5	no	16.789	16.760	EPSD	COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P49023	PXN	P27361	MAPK3	S303	S303R	303	Missense	central	0	yes	16.789	0.000	EPSD	COSMIC	9.358	Loss
CMGC_MAPK_ERK1_MAPK3_ST	P49023	PXN	P27361	MAPK3	S303	G306R	306	Missense	distal	3	no	16.789	16.783	EPSD	COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P49023	PXN	P27361	MAPK3	S303	R301Q	301	Missense	proximal	-2	no	16.789	16.425	EPSD	COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P49023	PXN	P27361	MAPK3	S303	G299S	299	Missense	distal	-4	no	16.789	16.828	EPSD	COSMIC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P49023	PXN	P27361	MAPK3	S320	S322A	322	Missense	proximal	2	no	10.939	10.900	EPSD	COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P49023	PXN	P27361	MAPK3	S322	P328S	328	Missense	distal	6	no	17.609	17.739	EPSD	COSMIC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P49023	PXN	P27361	MAPK3	S322	S322A	322	Missense	central	0	yes	17.609	0.000	EPSD	COSMIC	9.358	Loss
CMGC_MAPK_ERK1_MAPK3_ST	P49023	PXN	P27361	MAPK3	S332	P328S	328	Missense	distal	-4	no	10.497	10.525	EPSD	COSMIC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P49023	PXN	P27361	MAPK3	S332	L338P	338	Missense	distal	6	no	10.497	10.724	EPSD	COSMIC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P49023	PXN	P27361	MAPK3	S332	G331W	331	Missense	proximal	-1	no	10.497	10.283	EPSD	COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P49023	PXN	P27361	MAPK3	S340	L338P	338	Missense	proximal	-2	no	8.495	9.880	EPSD	COSMIC	9.358	Gain
CMGC_MAPK_ERK1_MAPK3_ST	P49023	PXN	P27361	MAPK3	S414	K407E	407	Missense	distal	-7	no	16.600	16.548	EPSD	COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P49023	PXN	P27361	MAPK3	S414	R416H	416	Missense	proximal	2	no	16.600	16.597	EPSD	COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P49023	PXN	P27361	MAPK3	S414	F413L	413	Missense	proximal	-1	no	16.600	16.715	EPSD	COSMIC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P42224	STAT1	P27361	MAPK3	S485	P491L	491	Missense	distal	6	no	10.553	10.326	EPSD	COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P42224	STAT1	P27361	MAPK3	S485	P491A	491	Missense	distal	6	no	10.553	10.157	EPSD	COSMIC;GDSC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P42224	STAT1	P27361	MAPK3	S485	A479V	479	Missense	distal	-6	no	10.553	10.539	EPSD	COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P42224	STAT1	P27361	MAPK3	T489	P491L	491	Missense	proximal	2	no	11.420	11.398	EPSD	COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P42224	STAT1	P27361	MAPK3	T489	P491A	491	Missense	proximal	2	no	11.420	11.383	EPSD	COSMIC;GDSC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P42224	STAT1	P27361	MAPK3	S532	D534Y	534	Missense	proximal	2	no	18.108	18.098	EPSD	COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P42224	STAT1	P27361	MAPK3	S606	R608Q	608	Missense	proximal	2	no	10.573	10.564	EPSD	COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P42224	STAT1	P27361	MAPK3	S727	E730K	730	Missense	distal	3	no	21.132	21.121	PhosphoSitePlus	COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P14618	PKM	P27361	MAPK3	T25	A20T	20	Missense	distal	-5	no	9.773	9.856	EPSD	COSMIC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P14618	PKM	P27361	MAPK3	T25	R32L	32	Missense	distal	7	no	9.773	9.873	EPSD	COSMIC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P14618	PKM	P27361	MAPK3	S37	R32L	32	Missense	distal	-5	no	16.418	16.404	PhosphoSitePlus	COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P14618	PKM	P27361	MAPK3	T80	H81P	81	Missense	proximal	1	no	8.102	15.858	EPSD	COSMIC	9.358	Gain
CMGC_MAPK_ERK1_MAPK3_ST	P14618	PKM	P27361	MAPK3	S97	I103T	103	Missense	distal	6	no	9.239	9.654	EPSD	COSMIC	9.358	Gain
CMGC_MAPK_ERK1_MAPK3_ST	P14618	PKM	P27361	MAPK3	S243	F244L	244	Missense	proximal	1	no	10.490	7.666	EPSD	COSMIC	9.358	Loss
CMGC_MAPK_ERK1_MAPK3_ST	P14618	PKM	P27361	MAPK3	S243	M239I	239	Missense	distal	-4	no	10.490	10.511	EPSD	COSMIC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P14618	PKM	P27361	MAPK3	S420	G415R	415	Missense	distal	-5	no	11.313	11.311	EPSD	COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P14618	PKM	P27361	MAPK3	S420	E418D	418	Missense	proximal	-2	no	11.313	11.352	EPSD	COSMIC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P14618	PKM	P27361	MAPK3	S420	S420F	420	Missense	central	0	yes	11.313	0.000	EPSD	COSMIC	9.358	Loss
CMGC_MAPK_ERK1_MAPK3_ST	P14618	PKM	P27361	MAPK3	S420	V414M	414	Missense	distal	-6	no	11.313	11.221	EPSD	COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P14618	PKM	P27361	MAPK3	S420	G415D	415	Missense	distal	-5	no	11.313	11.322	EPSD	COSMIC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P14618	PKM	P27361	MAPK3	S420	A413T	413	Missense	distal	-7	no	11.313	11.240	EPSD	COSMIC;GDSC;CCLE	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P14618	PKM	P27361	MAPK3	S420	A427V	427	Missense	distal	7	no	11.313	11.285	EPSD	COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P56270	MAZ	P27361	MAPK3	T72	A78V	78	Missense	distal	6	no	15.569	15.657	PhosphoSitePlus	COSMIC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P56270	MAZ	P27361	MAPK3	T72	A68T	68	Missense	distal	-4	no	15.569	15.643	PhosphoSitePlus	COSMIC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P56270	MAZ	P27361	MAPK3	S323	D330A	330	Missense	distal	7	no	10.768	11.008	EPSD	COSMIC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P56270	MAZ	P27361	MAPK3	S468	A462V	462	Missense	distal	-6	no	12.051	12.037	EPSD	COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P56270	MAZ	P27361	MAPK3	S468	E463G	463	Missense	distal	-5	no	12.051	12.042	EPSD	COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P56270	MAZ	P27361	MAPK3	S468	G461E	461	Missense	distal	-7	no	12.051	12.045	EPSD	COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P56270	MAZ	P27361	MAPK3	S469	A462V	462	Missense	distal	-7	no	12.228	12.227	EPSD	COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P56270	MAZ	P27361	MAPK3	S469	E463G	463	Missense	distal	-6	no	12.228	12.182	EPSD	COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q9BUB5	MKNK1	P27361	MAPK3	S221	E220K	220	Missense	proximal	-1	no	12.818	12.788	EPSD	COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q9BUB5	MKNK1	P27361	MAPK3	S221	P214S	214	Missense	distal	-7	no	12.818	12.781	EPSD	COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q9BUB5	MKNK1	P27361	MAPK3	S221	N216I	216	Missense	distal	-5	no	12.818	12.765	EPSD	COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q9BUB5	MKNK1	P27361	MAPK3	S226	D232Y	232	Missense	distal	6	no	15.959	15.753	EPSD	COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q9BUB5	MKNK1	P27361	MAPK3	S226	E220K	220	Missense	distal	-6	no	15.959	15.817	EPSD	COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q9BUB5	MKNK1	P27361	MAPK3	T250	T249P	249	Missense	proximal	-1	no	14.883	14.920	EPSD	COSMIC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q9BUB5	MKNK1	P27361	MAPK3	T250	T249I	249	Missense	proximal	-1	no	14.883	14.782	EPSD	COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q9BUB5	MKNK1	P27361	MAPK3	T250	T254S	254	Missense	distal	4	no	14.883	14.996	EPSD	COSMIC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q9BUB5	MKNK1	P27361	MAPK3	T250	S244Y	244	Missense	distal	-6	no	14.883	14.630	EPSD	COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q9BUB5	MKNK1	P27361	MAPK3	T255	T249P	249	Missense	distal	-6	no	17.074	17.158	EPSD	COSMIC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q9BUB5	MKNK1	P27361	MAPK3	T255	G258D	258	Missense	distal	3	no	17.074	17.079	EPSD	COSMIC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q9BUB5	MKNK1	P27361	MAPK3	T255	T249I	249	Missense	distal	-6	no	17.074	16.844	EPSD	COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q9BUB5	MKNK1	P27361	MAPK3	T255	T254S	254	Missense	proximal	-1	no	17.074	17.105	EPSD	COSMIC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q9BUB5	MKNK1	P27361	MAPK3	T385	P384H	384	Missense	proximal	-1	no	14.907	14.862	PhosphoSitePlus	COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q9BUB5	MKNK1	P27361	MAPK3	T385	T385P	385	Missense	central	0	yes	14.907	0.000	PhosphoSitePlus	COSMIC	9.358	Loss
CMGC_MAPK_ERK1_MAPK3_ST	Q9BUB5	MKNK1	P27361	MAPK3	T385	P386L	386	Missense	proximal	1	no	14.907	5.869	PhosphoSitePlus	COSMIC;GDSC;CCLE	9.358	Loss
CMGC_MAPK_ERK1_MAPK3_ST	Q9BUB5	MKNK1	P27361	MAPK3	T385	L383P	383	Missense	proximal	-2	no	14.907	16.291	PhosphoSitePlus	COSMIC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q9BUB5	MKNK1	P27361	MAPK3	T385	L383F	383	Missense	proximal	-2	no	14.907	13.915	PhosphoSitePlus	COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q9BUB5	MKNK1	P27361	MAPK3	T385	P384L	384	Missense	proximal	-1	no	14.907	14.812	PhosphoSitePlus	COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q9BUB5	MKNK1	P27361	MAPK3	T385	K381E	381	Missense	distal	-4	no	14.907	14.967	PhosphoSitePlus	COSMIC;GDSC;CCLE	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q9BUB5	MKNK1	P27361	MAPK3	S437	L431P	431	Missense	distal	-6	no	17.038	17.285	EPSD	COSMIC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q9BUB5	MKNK1	P27361	MAPK3	S437	K435N	435	Missense	proximal	-2	no	17.038	17.358	EPSD	COSMIC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q9BUB5	MKNK1	P27361	MAPK3	S437	C440F	440	Missense	distal	3	no	17.038	17.059	EPSD	COSMIC;GDSC;CCLE	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q9BUB5	MKNK1	P27361	MAPK3	S460	P461L	461	Missense	proximal	1	no	19.168	10.130	EPSD	COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q9BUB5	MKNK1	P27361	MAPK3	S460	G456V	456	Missense	distal	-4	no	19.168	19.054	EPSD	COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q9UJY1	HSPB8	P27361	MAPK3	S24	P20L	20	Missense	distal	-4	no	19.917	19.804	PhosphoSitePlus;EPSD	COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q9UJY1	HSPB8	P27361	MAPK3	S24	P20T	20	Missense	distal	-4	no	19.917	19.886	PhosphoSitePlus;EPSD	COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q9UJY1	HSPB8	P27361	MAPK3	S24	R22Q	22	Missense	proximal	-2	no	19.917	19.553	PhosphoSitePlus;EPSD	COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q9UJY1	HSPB8	P27361	MAPK3	S24	P25L	25	Missense	proximal	1	no	19.917	10.879	PhosphoSitePlus;EPSD	COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q9UJY1	HSPB8	P27361	MAPK3	S24	R17C	17	Missense	distal	-7	no	19.917	20.104	PhosphoSitePlus;EPSD	COSMIC;GDSC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q9UJY1	HSPB8	P27361	MAPK3	S24	R22W	22	Missense	proximal	-2	no	19.917	18.020	PhosphoSitePlus;EPSD	COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q9UJY1	HSPB8	P27361	MAPK3	S27	P20L	20	Missense	distal	-7	no	11.443	11.550	EPSD;PhosphoSitePlus	COSMIC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q9UJY1	HSPB8	P27361	MAPK3	S27	P20T	20	Missense	distal	-7	no	11.443	11.482	EPSD;PhosphoSitePlus	COSMIC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q9UJY1	HSPB8	P27361	MAPK3	S27	R22Q	22	Missense	distal	-5	no	11.443	11.435	EPSD;PhosphoSitePlus	COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q9UJY1	HSPB8	P27361	MAPK3	S27	P25L	25	Missense	proximal	-2	no	11.443	10.059	EPSD;PhosphoSitePlus	COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q9UJY1	HSPB8	P27361	MAPK3	S27	R22W	22	Missense	distal	-5	no	11.443	11.289	EPSD;PhosphoSitePlus	COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q9UJY1	HSPB8	P27361	MAPK3	S27	D33N	33	Missense	distal	6	no	11.443	11.390	EPSD;PhosphoSitePlus	COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q9UJY1	HSPB8	P27361	MAPK3	S104	V102A	102	Missense	proximal	-2	no	11.361	10.665	EPSD	COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q05682	CALD1	P27361	MAPK3	S129	L130P	130	Missense	proximal	1	no	7.799	16.837	EPSD	COSMIC	9.358	Gain
CMGC_MAPK_ERK1_MAPK3_ST	Q05682	CALD1	P27361	MAPK3	T167	V168F	168	Missense	proximal	1	no	7.455	10.664	EPSD	COSMIC	9.358	Gain
CMGC_MAPK_ERK1_MAPK3_ST	Q05682	CALD1	P27361	MAPK3	S480	R484H	484	Missense	distal	4	no	10.179	10.185	EPSD	COSMIC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q05682	CALD1	P27361	MAPK3	S480	M482I	482	Missense	proximal	2	no	10.179	10.187	EPSD	COSMIC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q05682	CALD1	P27361	MAPK3	S480	R484Q	484	Missense	distal	4	no	10.179	10.134	EPSD	COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q05682	CALD1	P27361	MAPK3	S480	R484L	484	Missense	distal	4	no	10.179	10.122	EPSD	COSMIC;GDSC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q05682	CALD1	P27361	MAPK3	S480	R484G	484	Missense	distal	4	no	10.179	10.164	EPSD	COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q05682	CALD1	P27361	MAPK3	S480	E477K	477	Missense	distal	-3	no	10.179	10.147	EPSD	COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q05682	CALD1	P27361	MAPK3	T638	G641S	641	Missense	distal	3	no	13.188	13.203	EPSD	COSMIC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q05682	CALD1	P27361	MAPK3	T638	P633S	633	Missense	distal	-5	no	13.188	13.193	EPSD	COSMIC;GDSC;CCLE	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q05682	CALD1	P27361	MAPK3	S700	E707K	707	Missense	distal	7	no	9.340	9.411	EPSD	COSMIC	9.358	Gain
CMGC_MAPK_ERK1_MAPK3_ST	Q05682	CALD1	P27361	MAPK3	S724	T726I	726	Missense	proximal	2	no	15.284	15.260	EPSD	COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q05682	CALD1	P27361	MAPK3	T730	T726I	726	Missense	distal	-4	no	13.698	13.597	EPSD	COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q05682	CALD1	P27361	MAPK3	T730	N732H	732	Missense	proximal	2	no	13.698	13.700	EPSD	COSMIC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q05682	CALD1	P27361	MAPK3	T730	K733N	733	Missense	distal	3	no	13.698	13.701	EPSD	COSMIC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q05682	CALD1	P27361	MAPK3	T730	N732S	732	Missense	proximal	2	no	13.698	13.715	EPSD	COSMIC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q05682	CALD1	P27361	MAPK3	S759	S765F	765	Missense	distal	6	no	13.838	13.124	PhosphoSitePlus;EPSD	COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q05682	CALD1	P27361	MAPK3	S789	D785N	785	Missense	distal	-4	no	18.446	18.420	EPSD;PhosphoSitePlus	COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P14598	NCF1	P27361	MAPK3	S345	P349R	349	Missense	distal	4	no	16.846	16.749	EPSD;PhosphoSitePlus	COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P14598	NCF1	P27361	MAPK3	S348	P349R	349	Missense	proximal	1	no	18.072	8.571	PhosphoSitePlus;EPSD	COSMIC	9.358	Loss
CMGC_MAPK_ERK1_MAPK3_ST	P53004	BLVRA	P27361	MAPK3	S211	W215C	215	Missense	distal	4	no	14.049	14.159	EPSD	COSMIC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P53004	BLVRA	P27361	MAPK3	S230	R225Q	225	Missense	distal	-5	no	12.213	12.205	PhosphoSitePlus	COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P53004	BLVRA	P27361	MAPK3	S230	S235Y	235	Missense	distal	5	no	12.213	11.997	PhosphoSitePlus	COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P53004	BLVRA	P27361	MAPK3	S230	R227K	227	Missense	distal	-3	no	12.213	12.200	PhosphoSitePlus	COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P38936	CDKN1A	P27361	MAPK3	T57	D62Y	62	Missense	distal	5	no	13.226	13.052	EPSD	COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P38936	CDKN1A	P27361	MAPK3	T57	D62H	62	Missense	distal	5	no	13.226	13.160	EPSD	COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P38936	CDKN1A	P27361	MAPK3	T57	D52V	52	Missense	distal	-5	no	13.226	13.185	EPSD	COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P38936	CDKN1A	P27361	MAPK3	T57	T57R	57	Missense	central	0	yes	13.226	0.000	EPSD	COSMIC	9.358	Loss
CMGC_MAPK_ERK1_MAPK3_ST	P38936	CDKN1A	P27361	MAPK3	S98	T97I	97	Missense	proximal	-1	no	15.652	15.551	EPSD;PhosphoSitePlus	COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P38936	CDKN1A	P27361	MAPK3	S130	E125Q	125	Missense	distal	-5	no	16.417	16.399	PhosphoSitePlus;EPSD	COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P38936	CDKN1A	P27361	MAPK3	S130	S137T	137	Missense	distal	7	no	16.417	16.536	PhosphoSitePlus;EPSD	COSMIC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P38936	CDKN1A	P27361	MAPK3	S137	R143W	143	Missense	distal	6	no	10.411	9.589	EPSD	COSMIC;GDSC;CCLE	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P38936	CDKN1A	P27361	MAPK3	S137	Q138E	138	Missense	proximal	1	no	10.411	9.107	EPSD	COSMIC	9.358	Loss
CMGC_MAPK_ERK1_MAPK3_ST	P38936	CDKN1A	P27361	MAPK3	S137	G139C	139	Missense	proximal	2	no	10.411	10.367	EPSD	COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P38936	CDKN1A	P27361	MAPK3	T145	D149N	149	Missense	distal	4	no	9.904	9.877	EPSD	COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P38936	CDKN1A	P27361	MAPK3	T145	R143W	143	Missense	proximal	-2	no	9.904	8.008	EPSD	COSMIC;GDSC;CCLE	9.358	Loss
CMGC_MAPK_ERK1_MAPK3_ST	P38936	CDKN1A	P27361	MAPK3	T145	Q138E	138	Missense	distal	-7	no	9.904	9.855	EPSD	COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P38936	CDKN1A	P27361	MAPK3	T145	G139C	139	Missense	distal	-6	no	9.904	9.407	EPSD	COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q9NYA1	SPHK1	P27361	MAPK3	T193	L194P	194	Missense	proximal	1	no	5.047	14.085	EPSD	COSMIC	9.358	Gain
CMGC_MAPK_ERK1_MAPK3_ST	Q9NYA1	SPHK1	P27361	MAPK3	S225	G219A	219	Missense	distal	-6	no	17.081	16.827	PhosphoSitePlus	COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q92934	BAD	P27361	MAPK3	S25	A27T	27	Missense	proximal	2	no	18.920	18.947	EPSD	COSMIC;GDSC;CCLE	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q92934	BAD	P27361	MAPK3	S57	E53K	53	Missense	distal	-4	no	9.816	9.756	EPSD	COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q92934	BAD	P27361	MAPK3	S57	S59R	59	Missense	proximal	2	no	9.816	9.803	EPSD	COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q92934	BAD	P27361	MAPK3	S75	A78E	78	Missense	distal	3	no	11.801	11.832	PhosphoSitePlus	COSMIC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q92934	BAD	P27361	MAPK3	S91	S97P	97	Missense	distal	6	no	16.824	16.694	EPSD	COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q92934	BAD	P27361	MAPK3	S91	R98H	98	Missense	distal	7	no	16.824	16.791	EPSD	COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q92934	BAD	P27361	MAPK3	S97	R98H	98	Missense	proximal	1	no	8.023	9.768	EPSD	COSMIC	9.358	Gain
CMGC_MAPK_ERK1_MAPK3_ST	Q92934	BAD	P27361	MAPK3	S124	S124F	124	Missense	central	0	yes	10.499	0.000	EPSD	COSMIC	9.358	Loss
CMGC_MAPK_ERK1_MAPK3_ST	Q92934	BAD	P27361	MAPK3	S124	K127N	127	Missense	distal	3	no	10.499	10.502	EPSD	COSMIC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q92934	BAD	P27361	MAPK3	T139	K133N	133	Missense	distal	-6	no	9.743	9.778	EPSD	COSMIC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q92934	BAD	P27361	MAPK3	S144	W147R	147	Missense	distal	3	no	9.462	9.540	EPSD	COSMIC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q92934	BAD	P27361	MAPK3	S146	W147R	147	Missense	proximal	1	no	12.087	10.490	EPSD	COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q92934	BAD	P27361	MAPK3	S153	W147R	147	Missense	distal	-6	no	9.155	9.677	EPSD	COSMIC	9.358	Gain
CMGC_MAPK_ERK1_MAPK3_ST	Q9H8Y8	GORASP2	P27361	MAPK3	T222	P223H	223	Missense	proximal	1	no	14.203	6.447	PhosphoSitePlus;EPSD	COSMIC	9.358	Loss
CMGC_MAPK_ERK1_MAPK3_ST	Q9H8Y8	GORASP2	P27361	MAPK3	T222	P226S	226	Missense	distal	4	no	14.203	14.252	PhosphoSitePlus;EPSD	COSMIC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q9H8Y8	GORASP2	P27361	MAPK3	T222	D229N	229	Missense	distal	7	no	14.203	14.262	PhosphoSitePlus;EPSD	COSMIC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q9H8Y8	GORASP2	P27361	MAPK3	T225	P223H	223	Missense	proximal	-2	no	14.707	13.479	EPSD;PhosphoSitePlus	COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q9H8Y8	GORASP2	P27361	MAPK3	T225	P226S	226	Missense	proximal	1	no	14.707	5.653	EPSD;PhosphoSitePlus	COSMIC	9.358	Loss
CMGC_MAPK_ERK1_MAPK3_ST	Q9H8Y8	GORASP2	P27361	MAPK3	T225	D229N	229	Missense	distal	4	no	14.707	14.680	EPSD;PhosphoSitePlus	COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q9H8Y8	GORASP2	P27361	MAPK3	S245	S243Y	243	Missense	proximal	-2	no	16.426	16.193	EPSD	COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q9H8Y8	GORASP2	P27361	MAPK3	S245	P241S	241	Missense	distal	-4	no	16.426	16.454	EPSD	COSMIC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q9H8Y8	GORASP2	P27361	MAPK3	S245	I252M	252	Missense	distal	7	no	16.426	16.478	EPSD	COSMIC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q9H8Y8	GORASP2	P27361	MAPK3	T415	P416S	416	Missense	proximal	1	no	13.920	4.867	EPSD	COSMIC	9.358	Loss
CMGC_MAPK_ERK1_MAPK3_ST	Q9H8Y8	GORASP2	P27361	MAPK3	S441	A446V	446	Missense	distal	5	no	10.611	10.600	EPSD	COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q9H8Y8	GORASP2	P27361	MAPK3	S451	E450V	450	Missense	proximal	-1	no	18.525	18.466	EPSD	COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q9H8Y8	GORASP2	P27361	MAPK3	S451	A446V	446	Missense	distal	-5	no	18.525	18.548	EPSD	COSMIC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P19793	RXRA	P27361	MAPK3	S49	P50S	50	Missense	proximal	1	no	16.919	7.865	EPSD	COSMIC;GDSC;CCLE	9.358	Loss
CMGC_MAPK_ERK1_MAPK3_ST	P19793	RXRA	P27361	MAPK3	T82	G86C	86	Missense	distal	4	no	16.644	16.301	EPSD	COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P19793	RXRA	P27361	MAPK3	S225	D229G	229	Missense	distal	4	no	9.861	9.820	EPSD	COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P19793	RXRA	P27361	MAPK3	S225	S222L	222	Missense	distal	-3	no	9.861	9.786	EPSD	COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P19793	RXRA	P27361	MAPK3	S260	M254I	254	Missense	distal	-6	no	19.444	19.467	PhosphoSitePlus	COSMIC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P78536	ADAM17	P27361	MAPK3	S770	E774K	774	Missense	distal	4	no	11.205	11.167	EPSD	COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P78536	ADAM17	P27361	MAPK3	S770	D765N	765	Missense	distal	-5	no	11.205	11.200	EPSD	COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q8WX93	PALLD	P27361	MAPK3	S9	D16Y	16	Missense	distal	7	no	9.510	9.659	EPSD	COSMIC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q8WX93	PALLD	P27361	MAPK3	S9	G3E	3	Missense	distal	-6	no	9.510	9.556	EPSD	COSMIC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q8WX93	PALLD	P27361	MAPK3	S9	F10L	10	Missense	proximal	1	no	9.510	6.686	EPSD	COSMIC;CCLE	9.358	Loss
CMGC_MAPK_ERK1_MAPK3_ST	Q8WX93	PALLD	P27361	MAPK3	S15	D16Y	16	Missense	proximal	1	no	10.249	11.802	EPSD	COSMIC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q8WX93	PALLD	P27361	MAPK3	S15	F10L	10	Missense	distal	-5	no	10.249	10.324	EPSD	COSMIC;CCLE	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q8WX93	PALLD	P27361	MAPK3	S71	P72T	72	Missense	proximal	1	no	15.044	6.167	EPSD	COSMIC	9.358	Loss
CMGC_MAPK_ERK1_MAPK3_ST	Q8WX93	PALLD	P27361	MAPK3	S71	I64F	64	Missense	distal	-7	no	15.044	15.072	EPSD	COSMIC;CCLE	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q8WX93	PALLD	P27361	MAPK3	T100	E107Q	107	Missense	distal	7	no	14.893	14.988	EPSD	COSMIC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q8WX93	PALLD	P27361	MAPK3	S115	P116S	116	Missense	proximal	1	no	16.440	7.387	EPSD	COSMIC	9.358	Loss
CMGC_MAPK_ERK1_MAPK3_ST	Q8WX93	PALLD	P27361	MAPK3	S115	I113N	113	Missense	proximal	-2	no	16.440	16.259	EPSD	COSMIC;CCLE	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q8WX93	PALLD	P27361	MAPK3	S132	R135G	135	Missense	distal	3	no	9.644	9.650	EPSD	COSMIC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q8WX93	PALLD	P27361	MAPK3	S132	S136G	136	Missense	distal	4	no	9.644	9.483	EPSD	COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q8WX93	PALLD	P27361	MAPK3	T147	V152I	152	Missense	distal	5	no	13.536	13.410	EPSD	COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q8WX93	PALLD	P27361	MAPK3	T147	R143H	143	Missense	distal	-4	no	13.536	13.550	EPSD	COSMIC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q8WX93	PALLD	P27361	MAPK3	S166	Q159K	159	Missense	distal	-7	no	9.452	9.454	EPSD	COSMIC;GDSC;CCLE	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q8WX93	PALLD	P27361	MAPK3	S166	Q167E	167	Missense	proximal	1	no	9.452	8.148	EPSD	COSMIC	9.358	Loss
CMGC_MAPK_ERK1_MAPK3_ST	Q8WX93	PALLD	P27361	MAPK3	S192	G195E	195	Missense	distal	3	no	13.583	13.585	EPSD	COSMIC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q8WX93	PALLD	P27361	MAPK3	S192	K187R	187	Missense	distal	-5	no	13.583	13.584	EPSD	COSMIC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q8WX93	PALLD	P27361	MAPK3	S199	D201H	201	Missense	proximal	2	no	15.780	15.776	EPSD	COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q8WX93	PALLD	P27361	MAPK3	S199	S206P	206	Missense	distal	7	no	15.780	15.857	EPSD	COSMIC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q8WX93	PALLD	P27361	MAPK3	S199	G195E	195	Missense	distal	-4	no	15.780	15.794	EPSD	COSMIC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q8WX93	PALLD	P27361	MAPK3	S206	N209D	209	Missense	distal	3	no	15.447	15.458	EPSD	COSMIC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q8WX93	PALLD	P27361	MAPK3	S206	D201H	201	Missense	distal	-5	no	15.447	15.446	EPSD	COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q8WX93	PALLD	P27361	MAPK3	S206	S206P	206	Missense	central	0	yes	15.447	0.000	EPSD	COSMIC	9.358	Loss
CMGC_MAPK_ERK1_MAPK3_ST	Q8WX93	PALLD	P27361	MAPK3	S222	M224I	224	Missense	proximal	2	no	17.496	17.505	EPSD	COSMIC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q8WX93	PALLD	P27361	MAPK3	S222	M224T	224	Missense	proximal	2	no	17.496	17.529	EPSD	COSMIC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q8WX93	PALLD	P27361	MAPK3	S222	E225A	225	Missense	distal	3	no	17.496	17.465	EPSD	COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q8WX93	PALLD	P27361	MAPK3	S236	M230I	230	Missense	distal	-6	no	13.902	13.926	EPSD	COSMIC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q8WX93	PALLD	P27361	MAPK3	S236	P237S	237	Missense	proximal	1	no	13.902	4.849	EPSD	COSMIC	9.358	Loss
CMGC_MAPK_ERK1_MAPK3_ST	Q8WX93	PALLD	P27361	MAPK3	S236	G238E	238	Missense	proximal	2	no	13.902	13.910	EPSD	COSMIC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q8WX93	PALLD	P27361	MAPK3	S236	G238V	238	Missense	proximal	2	no	13.902	13.894	EPSD	COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q8WX93	PALLD	P27361	MAPK3	S236	S236Y	236	Missense	central	0	yes	13.902	0.000	EPSD	COSMIC;GDSC;CCLE	9.358	Loss
CMGC_MAPK_ERK1_MAPK3_ST	Q8WX93	PALLD	P27361	MAPK3	S401	P402S	402	Missense	proximal	1	no	16.434	7.380	EPSD	COSMIC	9.358	Loss
CMGC_MAPK_ERK1_MAPK3_ST	Q8WX93	PALLD	P27361	MAPK3	S401	G405R	405	Missense	distal	4	no	16.434	16.448	EPSD	COSMIC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q8WX93	PALLD	P27361	MAPK3	S401	S399L	399	Missense	proximal	-2	no	16.434	16.126	EPSD	COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q8WX93	PALLD	P27361	MAPK3	S401	P402Q	402	Missense	proximal	1	no	16.434	8.490	EPSD	COSMIC	9.358	Loss
CMGC_MAPK_ERK1_MAPK3_ST	Q8WX93	PALLD	P27361	MAPK3	S423	T425N	425	Missense	proximal	2	no	15.594	15.588	EPSD	COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q8WX93	PALLD	P27361	MAPK3	S484	G478R	478	Missense	distal	-6	no	15.389	15.291	EPSD	COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q8WX93	PALLD	P27361	MAPK3	S484	R488Q	488	Missense	distal	4	no	15.389	15.345	EPSD	COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q8WX93	PALLD	P27361	MAPK3	S484	G478V	478	Missense	distal	-6	no	15.389	15.122	EPSD	COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q8WX93	PALLD	P27361	MAPK3	S484	G478W	478	Missense	distal	-6	no	15.389	14.769	EPSD	COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q8WX93	PALLD	P27361	MAPK3	T751	S755Y	755	Missense	distal	4	no	16.181	15.965	EPSD	COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q8WX93	PALLD	P27361	MAPK3	S754	S755Y	755	Missense	proximal	1	no	9.171	11.176	EPSD	COSMIC	9.358	Gain
CMGC_MAPK_ERK1_MAPK3_ST	Q8WX93	PALLD	P27361	MAPK3	S755	S755Y	755	Missense	central	0	yes	14.535	0.000	EPSD	COSMIC	9.358	Loss
CMGC_MAPK_ERK1_MAPK3_ST	Q8WX93	PALLD	P27361	MAPK3	S830	S835Y	835	Missense	distal	5	no	15.452	15.236	EPSD	COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q8WX93	PALLD	P27361	MAPK3	S830	S835A	835	Missense	distal	5	no	15.452	15.197	EPSD	COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q8WX93	PALLD	P27361	MAPK3	S839	S835Y	835	Missense	distal	-4	no	14.054	13.951	EPSD	COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q8WX93	PALLD	P27361	MAPK3	S839	S835A	835	Missense	distal	-4	no	14.054	13.922	EPSD	COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q8WX93	PALLD	P27361	MAPK3	T877	P878A	878	Missense	proximal	1	no	13.510	4.270	EPSD	COSMIC	9.358	Loss
CMGC_MAPK_ERK1_MAPK3_ST	Q9UBN7	HDAC6	P27361	MAPK3	S22	P20R	20	Missense	proximal	-2	no	19.697	18.297	EPSD	COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q9UBN7	HDAC6	P27361	MAPK3	S27	Q25R	25	Missense	proximal	-2	no	9.165	9.528	EPSD	COSMIC;CCLE	9.358	Gain
CMGC_MAPK_ERK1_MAPK3_ST	Q9UBN7	HDAC6	P27361	MAPK3	S28	Q25R	25	Missense	distal	-3	no	9.646	9.653	EPSD	COSMIC;CCLE	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q9UBN7	HDAC6	P27361	MAPK3	S28	N34S	34	Missense	distal	6	no	9.646	9.874	EPSD	COSMIC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q9UBN7	HDAC6	P27361	MAPK3	S412	P416S	416	Missense	distal	4	no	14.743	14.792	EPSD	COSMIC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q9UBN7	HDAC6	P27361	MAPK3	T527	P528Q	528	Missense	proximal	1	no	14.189	6.245	EPSD	COSMIC	9.358	Loss
CMGC_MAPK_ERK1_MAPK3_ST	Q9UBN7	HDAC6	P27361	MAPK3	T527	G521R	521	Missense	distal	-6	no	14.189	14.091	EPSD	COSMIC;GDSC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q9UBN7	HDAC6	P27361	MAPK3	T527	R529C	529	Missense	proximal	2	no	14.189	14.140	EPSD	COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q9UBN7	HDAC6	P27361	MAPK3	S886	G880V	880	Missense	distal	-6	no	9.709	9.441	EPSD	COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q9UBN7	HDAC6	P27361	MAPK3	S886	G888W	888	Missense	proximal	2	no	9.709	9.653	EPSD	COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q9UBN7	HDAC6	P27361	MAPK3	T1021	S1026I	1026	Missense	distal	5	no	15.977	15.584	EPSD	COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q9UBN7	HDAC6	P27361	MAPK3	T1021	S1025L	1025	Missense	distal	4	no	15.977	15.773	EPSD	COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q9UBN7	HDAC6	P27361	MAPK3	T1021	G1014W	1014	Missense	distal	-7	no	15.977	16.268	EPSD	COSMIC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q9UBN7	HDAC6	P27361	MAPK3	T1021	T1016N	1016	Missense	distal	-5	no	15.977	15.952	EPSD	COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q9UBN7	HDAC6	P27361	MAPK3	T1031	P1032L	1032	Missense	proximal	1	no	16.435	7.397	EPSD;PhosphoSitePlus	COSMIC	9.358	Loss
CMGC_MAPK_ERK1_MAPK3_ST	Q9UBN7	HDAC6	P27361	MAPK3	T1031	S1026I	1026	Missense	distal	-5	no	16.435	16.341	EPSD;PhosphoSitePlus	COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q9UBN7	HDAC6	P27361	MAPK3	T1031	S1025L	1025	Missense	distal	-6	no	16.435	16.103	EPSD;PhosphoSitePlus	COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q9UBN7	HDAC6	P27361	MAPK3	S1035	P1032L	1032	Missense	distal	-3	no	17.446	17.362	PhosphoSitePlus;EPSD	COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q9UBN7	HDAC6	P27361	MAPK3	S1035	T1040P	1040	Missense	distal	5	no	17.446	17.538	PhosphoSitePlus;EPSD	COSMIC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q9UBN7	HDAC6	P27361	MAPK3	T1041	I1044M	1044	Missense	distal	3	no	14.772	14.762	EPSD	COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q9UBN7	HDAC6	P27361	MAPK3	T1041	T1040P	1040	Missense	proximal	-1	no	14.772	14.809	EPSD	COSMIC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q9UBN7	HDAC6	P27361	MAPK3	T1048	I1044M	1044	Missense	distal	-4	no	9.982	9.961	EPSD	COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q9UBN7	HDAC6	P27361	MAPK3	S1062	Q1069H	1069	Missense	distal	7	no	9.401	9.339	EPSD	COSMIC	9.358	Loss
CMGC_MAPK_ERK1_MAPK3_ST	Q9UBN7	HDAC6	P27361	MAPK3	S1062	S1068F	1068	Missense	distal	6	no	9.401	8.687	EPSD	COSMIC;GDSC;CCLE	9.358	Loss
CMGC_MAPK_ERK1_MAPK3_ST	Q9UBN7	HDAC6	P27361	MAPK3	S1068	Q1069H	1069	Missense	proximal	1	no	10.297	10.486	EPSD	COSMIC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q9UBN7	HDAC6	P27361	MAPK3	S1068	S1068F	1068	Missense	central	0	yes	10.297	0.000	EPSD	COSMIC;GDSC;CCLE	9.358	Loss
CMGC_MAPK_ERK1_MAPK3_ST	Q04637	EIF4G1	P27361	MAPK3	S15	P21L	21	Missense	distal	6	no	15.941	15.714	EPSD	COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q04637	EIF4G1	P27361	MAPK3	S15	P10S	10	Missense	distal	-5	no	15.941	15.946	EPSD	COSMIC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q04637	EIF4G1	P27361	MAPK3	T43	Q49E	49	Missense	distal	6	no	12.683	12.862	EPSD	COSMIC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q04637	EIF4G1	P27361	MAPK3	T43	R48S	48	Missense	distal	5	no	12.683	12.826	EPSD	COSMIC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q04637	EIF4G1	P27361	MAPK3	T43	P44S	44	Missense	proximal	1	no	12.683	3.629	EPSD	COSMIC	9.358	Loss
CMGC_MAPK_ERK1_MAPK3_ST	Q04637	EIF4G1	P27361	MAPK3	S60	S64L	64	Missense	distal	4	no	9.815	9.611	EPSD	COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q04637	EIF4G1	P27361	MAPK3	S60	R55Q	55	Missense	distal	-5	no	9.815	9.807	EPSD	COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q04637	EIF4G1	P27361	MAPK3	S60	R55W	55	Missense	distal	-5	no	9.815	9.661	EPSD	COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q04637	EIF4G1	P27361	MAPK3	S60	P59L	59	Missense	proximal	-1	no	9.815	9.720	EPSD	COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q04637	EIF4G1	P27361	MAPK3	S134	T136M	136	Missense	proximal	2	no	16.905	16.873	EPSD	COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q04637	EIF4G1	P27361	MAPK3	S134	G139W	139	Missense	distal	5	no	16.905	16.358	EPSD	COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q04637	EIF4G1	P27361	MAPK3	S134	P131S	131	Missense	distal	-3	no	16.905	16.896	EPSD	COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q04637	EIF4G1	P27361	MAPK3	T205	G199D	199	Missense	distal	-6	no	13.845	13.846	EPSD	COSMIC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q04637	EIF4G1	P27361	MAPK3	T205	P208L	208	Missense	distal	3	no	13.845	13.808	EPSD	COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q04637	EIF4G1	P27361	MAPK3	T205	S204T	204	Missense	proximal	-1	no	13.845	13.814	EPSD	COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q04637	EIF4G1	P27361	MAPK3	T205	R201C	201	Missense	distal	-4	no	13.845	13.684	EPSD	COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q04637	EIF4G1	P27361	MAPK3	T205	R201H	201	Missense	distal	-4	no	13.845	13.859	EPSD	COSMIC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q04637	EIF4G1	P27361	MAPK3	T205	T211M	211	Missense	distal	6	no	13.845	13.351	EPSD	COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q04637	EIF4G1	P27361	MAPK3	T207	P208L	208	Missense	proximal	1	no	17.338	8.300	EPSD	COSMIC	9.358	Loss
CMGC_MAPK_ERK1_MAPK3_ST	Q04637	EIF4G1	P27361	MAPK3	T207	S204T	204	Missense	distal	-3	no	17.338	17.308	EPSD	COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q04637	EIF4G1	P27361	MAPK3	T207	G214S	214	Missense	distal	7	no	17.338	17.199	EPSD	COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q04637	EIF4G1	P27361	MAPK3	T207	R201C	201	Missense	distal	-6	no	17.338	16.939	EPSD	COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q04637	EIF4G1	P27361	MAPK3	T207	R201H	201	Missense	distal	-6	no	17.338	17.334	EPSD	COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q04637	EIF4G1	P27361	MAPK3	T207	T211M	211	Missense	distal	4	no	17.338	17.073	EPSD	COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q04637	EIF4G1	P27361	MAPK3	T223	G221S	221	Missense	proximal	-2	no	11.997	13.038	EPSD	COSMIC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q04637	EIF4G1	P27361	MAPK3	T223	I229N	229	Missense	distal	6	no	11.997	12.338	EPSD	COSMIC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q04637	EIF4G1	P27361	MAPK3	T223	T223M	223	Missense	central	0	yes	11.997	0.000	EPSD	COSMIC	9.358	Loss
CMGC_MAPK_ERK1_MAPK3_ST	Q04637	EIF4G1	P27361	MAPK3	S253	E256K	256	Missense	distal	3	no	15.425	15.414	EPSD	COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q04637	EIF4G1	P27361	MAPK3	S253	P250S	250	Missense	distal	-3	no	15.425	15.416	EPSD	COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q04637	EIF4G1	P27361	MAPK3	S253	S260L	260	Missense	distal	7	no	15.425	15.695	EPSD	COSMIC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q04637	EIF4G1	P27361	MAPK3	S253	G249C	249	Missense	distal	-4	no	15.425	15.225	EPSD	COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q04637	EIF4G1	P27361	MAPK3	S253	P248S	248	Missense	distal	-5	no	15.425	15.430	EPSD	COSMIC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q04637	EIF4G1	P27361	MAPK3	S253	S255L	255	Missense	proximal	2	no	15.425	15.401	EPSD	COSMIC;GDSC;CCLE	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q04637	EIF4G1	P27361	MAPK3	S257	E256K	256	Missense	proximal	-1	no	10.015	9.985	EPSD	COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q04637	EIF4G1	P27361	MAPK3	S257	P250S	250	Missense	distal	-7	no	10.015	9.978	EPSD	COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q04637	EIF4G1	P27361	MAPK3	S257	S260L	260	Missense	distal	3	no	10.015	9.983	EPSD	COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q04637	EIF4G1	P27361	MAPK3	S257	P264S	264	Missense	distal	7	no	10.015	9.938	EPSD	COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q04637	EIF4G1	P27361	MAPK3	S257	S255L	255	Missense	proximal	-2	no	10.015	9.707	EPSD	COSMIC;GDSC;CCLE	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q04637	EIF4G1	P27361	MAPK3	S261	E256K	256	Missense	distal	-5	no	18.445	18.433	EPSD	COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q04637	EIF4G1	P27361	MAPK3	S261	T265K	265	Missense	distal	4	no	18.445	18.419	EPSD	COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q04637	EIF4G1	P27361	MAPK3	S261	S260L	260	Missense	proximal	-1	no	18.445	18.356	EPSD	COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q04637	EIF4G1	P27361	MAPK3	S261	P264S	264	Missense	distal	3	no	18.445	18.440	EPSD	COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q04637	EIF4G1	P27361	MAPK3	S261	P266S	266	Missense	distal	5	no	18.445	18.488	EPSD	COSMIC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q04637	EIF4G1	P27361	MAPK3	S261	S255L	255	Missense	distal	-6	no	18.445	18.113	EPSD	COSMIC;GDSC;CCLE	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q04637	EIF4G1	P27361	MAPK3	S263	P270S	270	Missense	distal	7	no	16.762	16.685	EPSD	COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q04637	EIF4G1	P27361	MAPK3	S263	E256K	256	Missense	distal	-7	no	16.762	16.814	EPSD	COSMIC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q04637	EIF4G1	P27361	MAPK3	S263	T265K	265	Missense	proximal	2	no	16.762	16.757	EPSD	COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q04637	EIF4G1	P27361	MAPK3	S263	S260L	260	Missense	distal	-3	no	16.762	16.687	EPSD	COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q04637	EIF4G1	P27361	MAPK3	S263	S269Y	269	Missense	distal	6	no	16.762	16.380	EPSD	COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q04637	EIF4G1	P27361	MAPK3	S263	P264S	264	Missense	proximal	1	no	16.762	7.709	EPSD	COSMIC	9.358	Loss
CMGC_MAPK_ERK1_MAPK3_ST	Q04637	EIF4G1	P27361	MAPK3	S263	P266S	266	Missense	distal	3	no	16.762	16.757	EPSD	COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q04637	EIF4G1	P27361	MAPK3	S263	S269F	269	Missense	distal	6	no	16.762	16.048	EPSD	COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q04637	EIF4G1	P27361	MAPK3	T265	P270S	270	Missense	distal	5	no	17.256	17.299	EPSD	COSMIC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q04637	EIF4G1	P27361	MAPK3	T265	T265K	265	Missense	central	0	yes	17.256	0.000	EPSD	COSMIC	9.358	Loss
CMGC_MAPK_ERK1_MAPK3_ST	Q04637	EIF4G1	P27361	MAPK3	T265	S260L	260	Missense	distal	-5	no	17.256	17.197	EPSD	COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q04637	EIF4G1	P27361	MAPK3	T265	S269Y	269	Missense	distal	4	no	17.256	17.040	EPSD	COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q04637	EIF4G1	P27361	MAPK3	T265	P264S	264	Missense	proximal	-1	no	17.256	17.251	EPSD	COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q04637	EIF4G1	P27361	MAPK3	T265	P266S	266	Missense	proximal	1	no	17.256	8.203	EPSD	COSMIC	9.358	Loss
CMGC_MAPK_ERK1_MAPK3_ST	Q04637	EIF4G1	P27361	MAPK3	T265	S269F	269	Missense	distal	4	no	17.256	16.842	EPSD	COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q04637	EIF4G1	P27361	MAPK3	S267	P270S	270	Missense	distal	3	no	17.935	17.931	EPSD	COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q04637	EIF4G1	P27361	MAPK3	S267	T265K	265	Missense	proximal	-2	no	17.935	16.581	EPSD	COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q04637	EIF4G1	P27361	MAPK3	S267	P274S	274	Missense	distal	7	no	17.935	17.858	EPSD	COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q04637	EIF4G1	P27361	MAPK3	S267	S260L	260	Missense	distal	-7	no	17.935	18.080	EPSD	COSMIC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q04637	EIF4G1	P27361	MAPK3	S267	S269Y	269	Missense	proximal	2	no	17.935	17.914	EPSD	COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q04637	EIF4G1	P27361	MAPK3	S267	P264S	264	Missense	distal	-3	no	17.935	17.927	EPSD	COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q04637	EIF4G1	P27361	MAPK3	S267	P266S	266	Missense	proximal	-1	no	17.935	17.930	EPSD	COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q04637	EIF4G1	P27361	MAPK3	S267	S269F	269	Missense	proximal	2	no	17.935	17.885	EPSD	COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q04637	EIF4G1	P27361	MAPK3	S269	S276Y	276	Missense	distal	7	no	18.952	19.207	EPSD	COSMIC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q04637	EIF4G1	P27361	MAPK3	S269	S276F	276	Missense	distal	7	no	18.952	19.443	EPSD	COSMIC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q04637	EIF4G1	P27361	MAPK3	S269	P270S	270	Missense	proximal	1	no	18.952	9.899	EPSD	COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q04637	EIF4G1	P27361	MAPK3	S269	T265K	265	Missense	distal	-4	no	18.952	18.927	EPSD	COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q04637	EIF4G1	P27361	MAPK3	S269	P274S	274	Missense	distal	5	no	18.952	18.996	EPSD	COSMIC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q04637	EIF4G1	P27361	MAPK3	S269	S269Y	269	Missense	central	0	yes	18.952	0.000	EPSD	COSMIC	9.358	Loss
CMGC_MAPK_ERK1_MAPK3_ST	Q04637	EIF4G1	P27361	MAPK3	S269	P264S	264	Missense	distal	-5	no	18.952	18.958	EPSD	COSMIC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q04637	EIF4G1	P27361	MAPK3	S269	P266S	266	Missense	distal	-3	no	18.952	18.944	EPSD	COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q04637	EIF4G1	P27361	MAPK3	S269	S269F	269	Missense	central	0	yes	18.952	0.000	EPSD	COSMIC	9.358	Loss
CMGC_MAPK_ERK1_MAPK3_ST	Q04637	EIF4G1	P27361	MAPK3	T301	E306D	306	Missense	distal	5	no	14.959	14.941	EPSD	COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q04637	EIF4G1	P27361	MAPK3	T301	E298D	298	Missense	distal	-3	no	14.959	14.956	EPSD	COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q04637	EIF4G1	P27361	MAPK3	T301	E299D	299	Missense	proximal	-2	no	14.959	14.998	EPSD	COSMIC;GDSC;CCLE	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q04637	EIF4G1	P27361	MAPK3	T301	S300L	300	Missense	proximal	-1	no	14.959	14.870	EPSD	COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q04637	EIF4G1	P27361	MAPK3	S314	P315S	315	Missense	proximal	1	no	16.880	7.827	EPSD	COSMIC	9.358	Loss
CMGC_MAPK_ERK1_MAPK3_ST	Q04637	EIF4G1	P27361	MAPK3	S314	R312H	312	Missense	proximal	-2	no	16.880	17.052	EPSD	COSMIC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q04637	EIF4G1	P27361	MAPK3	T318	E322K	322	Missense	distal	4	no	15.004	14.966	EPSD	COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q04637	EIF4G1	P27361	MAPK3	T318	P315S	315	Missense	distal	-3	no	15.004	14.996	EPSD	COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q04637	EIF4G1	P27361	MAPK3	T318	R312H	312	Missense	distal	-6	no	15.004	15.000	EPSD	COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q04637	EIF4G1	P27361	MAPK3	S343	P350L	350	Missense	distal	7	no	16.407	16.600	EPSD	COSMIC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q04637	EIF4G1	P27361	MAPK3	S343	P350H	350	Missense	distal	7	no	16.407	16.467	EPSD	COSMIC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q04637	EIF4G1	P27361	MAPK3	S343	S341Y	341	Missense	proximal	-2	no	16.407	16.174	EPSD	COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q04637	EIF4G1	P27361	MAPK3	S343	L345F	345	Missense	proximal	2	no	16.407	16.380	EPSD	COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q04637	EIF4G1	P27361	MAPK3	S343	P344S	344	Missense	proximal	1	no	16.407	7.354	EPSD	COSMIC	9.358	Loss
CMGC_MAPK_ERK1_MAPK3_ST	Q04637	EIF4G1	P27361	MAPK3	T349	P350L	350	Missense	proximal	1	no	15.553	6.515	EPSD	COSMIC	9.358	Loss
CMGC_MAPK_ERK1_MAPK3_ST	Q04637	EIF4G1	P27361	MAPK3	T349	P350H	350	Missense	proximal	1	no	15.553	7.797	EPSD	COSMIC	9.358	Loss
CMGC_MAPK_ERK1_MAPK3_ST	Q04637	EIF4G1	P27361	MAPK3	T349	S353C	353	Missense	distal	4	no	15.553	15.049	EPSD	COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q04637	EIF4G1	P27361	MAPK3	T349	L345F	345	Missense	distal	-4	no	15.553	15.504	EPSD	COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q04637	EIF4G1	P27361	MAPK3	T349	P344S	344	Missense	distal	-5	no	15.553	15.558	EPSD	COSMIC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q04637	EIF4G1	P27361	MAPK3	S353	P350L	350	Missense	distal	-3	no	9.377	9.293	EPSD	COSMIC	9.358	Loss
CMGC_MAPK_ERK1_MAPK3_ST	Q04637	EIF4G1	P27361	MAPK3	S353	P350H	350	Missense	distal	-3	no	9.377	9.337	EPSD	COSMIC	9.358	Loss
CMGC_MAPK_ERK1_MAPK3_ST	Q04637	EIF4G1	P27361	MAPK3	S353	S353C	353	Missense	central	0	yes	9.377	0.000	EPSD	COSMIC	9.358	Loss
CMGC_MAPK_ERK1_MAPK3_ST	Q04637	EIF4G1	P27361	MAPK3	S353	H359R	359	Missense	distal	6	no	9.377	9.358	EPSD	COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q04637	EIF4G1	P27361	MAPK3	S409	S416L	416	Missense	distal	7	no	14.402	14.672	EPSD	COSMIC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q04637	EIF4G1	P27361	MAPK3	S409	D414N	414	Missense	distal	5	no	14.402	14.322	EPSD	COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q04637	EIF4G1	P27361	MAPK3	S409	P408S	408	Missense	proximal	-1	no	14.402	14.396	EPSD	COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q04637	EIF4G1	P27361	MAPK3	S409	G406V	406	Missense	distal	-3	no	14.402	14.363	EPSD	COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q04637	EIF4G1	P27361	MAPK3	S409	L404F	404	Missense	distal	-5	no	14.402	14.328	EPSD	COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q04637	EIF4G1	P27361	MAPK3	S409	A407D	407	Missense	proximal	-2	no	14.402	15.146	EPSD	COSMIC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q04637	EIF4G1	P27361	MAPK3	S409	S409L	409	Missense	central	0	yes	14.402	0.000	EPSD	COSMIC	9.358	Loss
CMGC_MAPK_ERK1_MAPK3_ST	Q04637	EIF4G1	P27361	MAPK3	S409	A412S	412	Missense	distal	3	no	14.402	14.446	EPSD	COSMIC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q04637	EIF4G1	P27361	MAPK3	S416	S416L	416	Missense	central	0	yes	15.309	0.000	EPSD	COSMIC	9.358	Loss
CMGC_MAPK_ERK1_MAPK3_ST	Q04637	EIF4G1	P27361	MAPK3	S416	D414N	414	Missense	proximal	-2	no	15.309	14.895	EPSD	COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q04637	EIF4G1	P27361	MAPK3	S416	E422Q	422	Missense	distal	6	no	15.309	15.129	EPSD	COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q04637	EIF4G1	P27361	MAPK3	S416	S409L	409	Missense	distal	-7	no	15.309	15.453	EPSD	COSMIC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q04637	EIF4G1	P27361	MAPK3	S416	A412S	412	Missense	distal	-4	no	15.309	15.440	EPSD	COSMIC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q04637	EIF4G1	P27361	MAPK3	T441	A440V	440	Missense	proximal	-1	no	15.263	15.312	EPSD	COSMIC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q04637	EIF4G1	P27361	MAPK3	T441	T436K	436	Missense	distal	-5	no	15.263	15.232	EPSD	COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q04637	EIF4G1	P27361	MAPK3	T441	P434L	434	Missense	distal	-7	no	15.263	15.370	EPSD	COSMIC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q04637	EIF4G1	P27361	MAPK3	T441	T444M	444	Missense	distal	3	no	15.263	15.214	EPSD	COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q04637	EIF4G1	P27361	MAPK3	T441	P434S	434	Missense	distal	-7	no	15.263	15.225	EPSD	COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q04637	EIF4G1	P27361	MAPK3	T441	S439F	439	Missense	proximal	-2	no	15.263	13.963	EPSD	COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q04637	EIF4G1	P27361	MAPK3	T441	P446S	446	Missense	distal	5	no	15.263	15.306	EPSD	COSMIC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q04637	EIF4G1	P27361	MAPK3	S450	M457I	457	Missense	distal	7	no	15.530	15.478	EPSD	COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q04637	EIF4G1	P27361	MAPK3	S450	M457V	457	Missense	distal	7	no	15.530	15.398	EPSD	COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q04637	EIF4G1	P27361	MAPK3	S450	E455D	455	Missense	distal	5	no	15.530	15.512	EPSD	COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q04637	EIF4G1	P27361	MAPK3	S450	T444M	444	Missense	distal	-6	no	15.530	15.277	EPSD	COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q04637	EIF4G1	P27361	MAPK3	S450	A452S	452	Missense	proximal	2	no	15.530	15.569	EPSD	COSMIC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q04637	EIF4G1	P27361	MAPK3	S450	P446S	446	Missense	distal	-4	no	15.530	15.557	EPSD	COSMIC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q04637	EIF4G1	P27361	MAPK3	S450	S450F	450	Missense	central	0	yes	15.530	0.000	EPSD	COSMIC	9.358	Loss
CMGC_MAPK_ERK1_MAPK3_ST	Q04637	EIF4G1	P27361	MAPK3	S450	E456G	456	Missense	distal	6	no	15.530	15.429	EPSD	COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q04637	EIF4G1	P27361	MAPK3	S488	A493T	493	Missense	distal	5	no	9.928	10.047	EPSD	COSMIC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q04637	EIF4G1	P27361	MAPK3	S488	I491T	491	Missense	distal	3	no	9.928	9.966	EPSD	COSMIC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q04637	EIF4G1	P27361	MAPK3	S488	E481Q	481	Missense	distal	-7	no	9.928	9.977	EPSD	COSMIC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q04637	EIF4G1	P27361	MAPK3	S488	P492Q	492	Missense	distal	4	no	9.928	9.786	EPSD	COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q04637	EIF4G1	P27361	MAPK3	T489	A493T	493	Missense	distal	4	no	14.445	14.663	EPSD	COSMIC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q04637	EIF4G1	P27361	MAPK3	T489	I491T	491	Missense	proximal	2	no	14.445	14.469	EPSD	COSMIC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q04637	EIF4G1	P27361	MAPK3	T489	P492Q	492	Missense	distal	3	no	14.445	14.418	EPSD	COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q04637	EIF4G1	P27361	MAPK3	S496	A502S	502	Missense	distal	6	no	8.986	9.512	EPSD	COSMIC	9.358	Gain
CMGC_MAPK_ERK1_MAPK3_ST	Q04637	EIF4G1	P27361	MAPK3	T647	R650W	650	Missense	distal	3	no	15.888	15.810	EPSD	COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q04637	EIF4G1	P27361	MAPK3	T647	K643R	643	Missense	distal	-4	no	15.888	15.895	EPSD	COSMIC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q04637	EIF4G1	P27361	MAPK3	T647	K643T	643	Missense	distal	-4	no	15.888	15.914	EPSD	COSMIC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q04637	EIF4G1	P27361	MAPK3	T647	K643N	643	Missense	distal	-4	no	15.888	15.911	EPSD	COSMIC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q04637	EIF4G1	P27361	MAPK3	T647	K643M	643	Missense	distal	-4	no	15.888	15.793	EPSD	COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q04637	EIF4G1	P27361	MAPK3	T667	N661H	661	Missense	distal	-6	no	14.292	14.250	EPSD	COSMIC;GDSC;CCLE	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q04637	EIF4G1	P27361	MAPK3	T667	D665Y	665	Missense	proximal	-2	no	14.292	14.590	EPSD	COSMIC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q04637	EIF4G1	P27361	MAPK3	T667	P668A	668	Missense	proximal	1	no	14.292	5.053	EPSD	COSMIC	9.358	Loss
CMGC_MAPK_ERK1_MAPK3_ST	Q04637	EIF4G1	P27361	MAPK3	T667	P668L	668	Missense	proximal	1	no	14.292	5.254	EPSD	COSMIC	9.358	Loss
CMGC_MAPK_ERK1_MAPK3_ST	Q04637	EIF4G1	P27361	MAPK3	T667	D665N	665	Missense	proximal	-2	no	14.292	13.879	EPSD	COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q04637	EIF4G1	P27361	MAPK3	T667	P668Q	668	Missense	proximal	1	no	14.292	6.348	EPSD	COSMIC	9.358	Loss
CMGC_MAPK_ERK1_MAPK3_ST	Q04637	EIF4G1	P27361	MAPK3	T667	P664T	664	Missense	distal	-3	no	14.292	14.254	EPSD	COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q04637	EIF4G1	P27361	MAPK3	S669	R675H	675	Missense	distal	6	no	10.901	10.920	EPSD	COSMIC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q04637	EIF4G1	P27361	MAPK3	S669	D665Y	665	Missense	distal	-4	no	10.901	10.834	EPSD	COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q04637	EIF4G1	P27361	MAPK3	S669	P668A	668	Missense	proximal	-1	no	10.901	10.762	EPSD	COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q04637	EIF4G1	P27361	MAPK3	S669	P668L	668	Missense	proximal	-1	no	10.901	10.807	EPSD	COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q04637	EIF4G1	P27361	MAPK3	S669	D665N	665	Missense	distal	-4	no	10.901	10.875	EPSD	COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q04637	EIF4G1	P27361	MAPK3	S669	P668Q	668	Missense	proximal	-1	no	10.901	10.815	EPSD	COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q04637	EIF4G1	P27361	MAPK3	S669	P664T	664	Missense	distal	-5	no	10.901	10.891	EPSD	COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q04637	EIF4G1	P27361	MAPK3	S669	R675Q	675	Missense	distal	6	no	10.901	10.832	EPSD	COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q04637	EIF4G1	P27361	MAPK3	S704	G698D	698	Missense	distal	-6	no	9.880	9.882	EPSD	COSMIC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q04637	EIF4G1	P27361	MAPK3	S704	A697V	697	Missense	distal	-7	no	9.880	9.879	EPSD	COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q04637	EIF4G1	P27361	MAPK3	S704	A697S	697	Missense	distal	-7	no	9.880	9.730	EPSD	COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q04637	EIF4G1	P27361	MAPK3	S704	L699M	699	Missense	distal	-5	no	9.880	9.822	EPSD	COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q04637	EIF4G1	P27361	MAPK3	S895	L896P	896	Missense	proximal	1	no	7.577	16.615	EPSD	COSMIC	9.358	Gain
CMGC_MAPK_ERK1_MAPK3_ST	Q04637	EIF4G1	P27361	MAPK3	S1041	R1042H	1042	Missense	proximal	1	no	7.650	9.395	EPSD	COSMIC	9.358	Gain
CMGC_MAPK_ERK1_MAPK3_ST	Q04637	EIF4G1	P27361	MAPK3	T1066	S1067P	1067	Missense	proximal	1	no	5.103	14.156	EPSD	COSMIC	9.358	Gain
CMGC_MAPK_ERK1_MAPK3_ST	Q04637	EIF4G1	P27361	MAPK3	S1110	A1108T	1108	Missense	proximal	-2	no	8.098	9.463	EPSD	COSMIC	9.358	Gain
CMGC_MAPK_ERK1_MAPK3_ST	Q04637	EIF4G1	P27361	MAPK3	T1179	R1173W	1173	Missense	distal	-6	no	14.976	14.454	EPSD	COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q04637	EIF4G1	P27361	MAPK3	T1179	T1182I	1182	Missense	distal	3	no	14.976	14.938	EPSD	COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q04637	EIF4G1	P27361	MAPK3	T1179	A1177G	1177	Missense	proximal	-2	no	14.976	15.211	EPSD	COSMIC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q04637	EIF4G1	P27361	MAPK3	T1179	D1175Y	1175	Missense	distal	-4	no	14.976	14.909	EPSD	COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q04637	EIF4G1	P27361	MAPK3	T1179	A1177V	1177	Missense	proximal	-2	no	14.976	15.673	EPSD	COSMIC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q04637	EIF4G1	P27361	MAPK3	T1179	R1176C	1176	Missense	distal	-3	no	14.976	14.836	EPSD	COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q04637	EIF4G1	P27361	MAPK3	T1179	R1178W	1178	Missense	proximal	-1	no	14.976	14.738	EPSD	COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q04637	EIF4G1	P27361	MAPK3	T1179	L1174F	1174	Missense	distal	-5	no	14.976	14.902	EPSD	COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q04637	EIF4G1	P27361	MAPK3	S1185	T1182I	1182	Missense	distal	-3	no	9.656	9.574	EPSD	COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q04637	EIF4G1	P27361	MAPK3	S1185	E1191D	1191	Missense	distal	6	no	9.656	9.611	EPSD	COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q04637	EIF4G1	P27361	MAPK3	S1185	R1178W	1178	Missense	distal	-7	no	9.656	9.901	EPSD	COSMIC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q04637	EIF4G1	P27361	MAPK3	S1185	S1187F	1187	Missense	proximal	2	no	9.656	9.605	EPSD	COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q04637	EIF4G1	P27361	MAPK3	S1185	S1187P	1187	Missense	proximal	2	no	9.656	9.654	EPSD	COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q04637	EIF4G1	P27361	MAPK3	S1185	E1192D	1192	Missense	distal	7	no	9.656	9.658	EPSD	COSMIC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q04637	EIF4G1	P27361	MAPK3	S1231	A1236V	1236	Missense	distal	5	no	15.873	15.862	EPSD	COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q04637	EIF4G1	P27361	MAPK3	S1231	A1226D	1226	Missense	distal	-5	no	15.873	15.938	EPSD	COSMIC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q04637	EIF4G1	P27361	MAPK3	S1231	A1225S	1225	Missense	distal	-6	no	15.873	16.190	EPSD	COSMIC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q04637	EIF4G1	P27361	MAPK3	S1231	A1236T	1236	Missense	distal	5	no	15.873	15.993	EPSD	COSMIC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q04637	EIF4G1	P27361	MAPK3	S1231	S1238C	1238	Missense	distal	7	no	15.873	16.485	EPSD	COSMIC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q04637	EIF4G1	P27361	MAPK3	S1231	A1235V	1235	Missense	distal	4	no	15.873	15.981	EPSD	COSMIC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q04637	EIF4G1	P27361	MAPK3	S1231	A1226S	1226	Missense	distal	-5	no	15.873	15.972	EPSD	COSMIC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q04637	EIF4G1	P27361	MAPK3	S1271	I1277F	1277	Missense	distal	6	no	14.412	14.268	EPSD	COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q04637	EIF4G1	P27361	MAPK3	S1271	S1273F	1273	Missense	proximal	2	no	14.412	14.362	EPSD	COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q04637	EIF4G1	P27361	MAPK3	S1271	V1266M	1266	Missense	distal	-5	no	14.412	14.369	EPSD	COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q04637	EIF4G1	P27361	MAPK3	S1271	L1275F	1275	Missense	distal	4	no	14.412	14.201	EPSD	COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q04637	EIF4G1	P27361	MAPK3	S1271	A1270T	1270	Missense	proximal	-1	no	14.412	14.515	EPSD	COSMIC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q04637	EIF4G1	P27361	MAPK3	S1271	S1273P	1273	Missense	proximal	2	no	14.412	14.410	EPSD	COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q04637	EIF4G1	P27361	MAPK3	T1495	I1491V	1491	Missense	distal	-4	no	13.357	13.365	EPSD	COSMIC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q04637	EIF4G1	P27361	MAPK3	T1495	P1496L	1496	Missense	proximal	1	no	13.357	4.319	EPSD	COSMIC	9.358	Loss
CMGC_MAPK_ERK1_MAPK3_ST	Q04637	EIF4G1	P27361	MAPK3	T1495	I1491T	1491	Missense	distal	-4	no	13.357	13.458	EPSD	COSMIC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q04637	EIF4G1	P27361	MAPK3	T1495	I1491N	1491	Missense	distal	-4	no	13.357	13.455	EPSD	COSMIC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q04637	EIF4G1	P27361	MAPK3	T1495	D1500G	1500	Missense	distal	5	no	13.357	13.335	EPSD	COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q04637	EIF4G1	P27361	MAPK3	T1495	I1492N	1492	Missense	distal	-3	no	13.357	13.424	EPSD	COSMIC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q04637	EIF4G1	P27361	MAPK3	T1495	I1492T	1492	Missense	distal	-3	no	13.357	13.439	EPSD	COSMIC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q04637	EIF4G1	P27361	MAPK3	T1495	I1492V	1492	Missense	distal	-3	no	13.357	13.396	EPSD	COSMIC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q04637	EIF4G1	P27361	MAPK3	T1495	T1495N	1495	Missense	central	0	yes	13.357	0.000	EPSD	COSMIC	9.358	Loss
CMGC_MAPK_ERK1_MAPK3_ST	P50616	TOB1	P27361	MAPK3	S14	F11C	11	Missense	distal	-3	no	9.455	9.419	EPSD	COSMIC;GDSC;CCLE	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P50616	TOB1	P27361	MAPK3	S147	D144N	144	Missense	distal	-3	no	10.821	10.799	EPSD	COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P50616	TOB1	P27361	MAPK3	S164	T166I	166	Missense	proximal	2	no	16.627	16.603	EPSD;PhosphoSitePlus	COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P50616	TOB1	P27361	MAPK3	S164	R170W	170	Missense	distal	6	no	16.627	15.804	EPSD;PhosphoSitePlus	COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P50616	TOB1	P27361	MAPK3	T166	T166I	166	Missense	central	0	yes	9.578	0.000	EPSD	COSMIC	9.358	Loss
CMGC_MAPK_ERK1_MAPK3_ST	P50616	TOB1	P27361	MAPK3	T166	R170W	170	Missense	distal	4	no	9.578	9.111	EPSD	COSMIC	9.358	Loss
CMGC_MAPK_ERK1_MAPK3_ST	P50616	TOB1	P27361	MAPK3	S205	L211F	211	Missense	distal	6	no	16.223	15.865	EPSD	COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P50616	TOB1	P27361	MAPK3	S268	P269A	269	Missense	proximal	1	no	16.658	7.418	EPSD	COSMIC	9.358	Loss
CMGC_MAPK_ERK1_MAPK3_ST	P50616	TOB1	P27361	MAPK3	S268	L267F	267	Missense	proximal	-1	no	16.658	16.542	EPSD	COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P49815	TSC2	P27361	MAPK3	T23	I17N	17	Missense	distal	-6	no	18.214	18.490	EPSD	COSMIC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P49815	TSC2	P27361	MAPK3	T23	G22R	22	Missense	proximal	-1	no	18.214	18.238	EPSD	COSMIC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P49815	TSC2	P27361	MAPK3	T23	G20E	20	Missense	distal	-3	no	18.214	18.227	EPSD	COSMIC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P49815	TSC2	P27361	MAPK3	S30	E32D	32	Missense	proximal	2	no	10.019	10.016	EPSD	COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P49815	TSC2	P27361	MAPK3	S30	G33R	33	Missense	distal	3	no	10.019	10.012	EPSD	COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P49815	TSC2	P27361	MAPK3	S540	S540F	540	Missense	central	0	yes	16.225	0.000	EPSD	COSMIC	9.358	Loss
CMGC_MAPK_ERK1_MAPK3_ST	P49815	TSC2	P27361	MAPK3	S540	P542L	542	Missense	proximal	2	no	16.225	16.203	EPSD	COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P49815	TSC2	P27361	MAPK3	S540	S538P	538	Missense	proximal	-2	no	16.225	17.301	EPSD	COSMIC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P49815	TSC2	P27361	MAPK3	S540	L539F	539	Missense	proximal	-1	no	16.225	16.110	EPSD	COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P49815	TSC2	P27361	MAPK3	S540	P543Q	543	Missense	distal	3	no	16.225	16.198	EPSD	COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P49815	TSC2	P27361	MAPK3	S664	P670S	670	Missense	distal	6	no	18.206	18.336	PhosphoSitePlus	COSMIC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P49815	TSC2	P27361	MAPK3	S664	P665F	665	Missense	proximal	1	no	18.206	11.993	PhosphoSitePlus	COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P49815	TSC2	P27361	MAPK3	S664	P665S	665	Missense	proximal	1	no	18.206	9.153	PhosphoSitePlus	COSMIC	9.358	Loss
CMGC_MAPK_ERK1_MAPK3_ST	P49815	TSC2	P27361	MAPK3	S664	P666S	666	Missense	proximal	2	no	18.206	18.208	PhosphoSitePlus	COSMIC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P49815	TSC2	P27361	MAPK3	S775	T771A	771	Missense	distal	-4	no	10.332	10.258	EPSD	COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P49815	TSC2	P27361	MAPK3	S775	A772T	772	Missense	distal	-3	no	10.332	10.393	EPSD	COSMIC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P49815	TSC2	P27361	MAPK3	S775	V769M	769	Missense	distal	-6	no	10.332	10.240	EPSD	COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P49815	TSC2	P27361	MAPK3	S775	V769A	769	Missense	distal	-6	no	10.332	10.345	EPSD	COSMIC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P49815	TSC2	P27361	MAPK3	S775	S775C	775	Missense	central	0	yes	10.332	0.000	EPSD	COSMIC	9.358	Loss
CMGC_MAPK_ERK1_MAPK3_ST	P49815	TSC2	P27361	MAPK3	S923	D925Y	925	Missense	proximal	2	no	11.019	11.008	EPSD	COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P49815	TSC2	P27361	MAPK3	S923	S918F	918	Missense	distal	-5	no	11.019	10.884	EPSD	COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P49815	TSC2	P27361	MAPK3	S923	E929D	929	Missense	distal	6	no	11.019	10.974	EPSD	COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P49815	TSC2	P27361	MAPK3	S923	P928S	928	Missense	distal	5	no	11.019	11.062	EPSD	COSMIC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P49815	TSC2	P27361	MAPK3	S923	P928L	928	Missense	distal	5	no	11.019	10.791	EPSD	COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P49815	TSC2	P27361	MAPK3	S923	L916R	916	Missense	distal	-7	no	11.019	10.957	EPSD	COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P49815	TSC2	P27361	MAPK3	S923	D926H	926	Missense	distal	3	no	11.019	11.015	EPSD	COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P49815	TSC2	P27361	MAPK3	S923	T927I	927	Missense	distal	4	no	11.019	10.790	EPSD	COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P49815	TSC2	P27361	MAPK3	T927	D925Y	925	Missense	proximal	-2	no	15.895	16.193	EPSD	COSMIC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P49815	TSC2	P27361	MAPK3	T927	E929D	929	Missense	proximal	2	no	15.895	15.892	EPSD	COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P49815	TSC2	P27361	MAPK3	T927	P928S	928	Missense	proximal	1	no	15.895	6.842	EPSD	COSMIC	9.358	Loss
CMGC_MAPK_ERK1_MAPK3_ST	P49815	TSC2	P27361	MAPK3	T927	P928L	928	Missense	proximal	1	no	15.895	6.857	EPSD	COSMIC	9.358	Loss
CMGC_MAPK_ERK1_MAPK3_ST	P49815	TSC2	P27361	MAPK3	T927	D926H	926	Missense	proximal	-1	no	15.895	15.903	EPSD	COSMIC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P49815	TSC2	P27361	MAPK3	T927	S932N	932	Missense	distal	5	no	15.895	15.773	EPSD	COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P49815	TSC2	P27361	MAPK3	T927	T927I	927	Missense	central	0	yes	15.895	0.000	EPSD	COSMIC	9.358	Loss
CMGC_MAPK_ERK1_MAPK3_ST	P49815	TSC2	P27361	MAPK3	S960	N958S	958	Missense	proximal	-2	no	14.575	15.519	EPSD	COSMIC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P49815	TSC2	P27361	MAPK3	S960	P962F	962	Missense	proximal	2	no	14.575	14.526	EPSD	COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P49815	TSC2	P27361	MAPK3	S960	P962S	962	Missense	proximal	2	no	14.575	14.577	EPSD	COSMIC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P49815	TSC2	P27361	MAPK3	S1002	S1002L	1002	Missense	central	0	yes	9.362	0.000	EPSD	COSMIC	9.358	Loss
CMGC_MAPK_ERK1_MAPK3_ST	P49815	TSC2	P27361	MAPK3	S1002	V1008M	1008	Missense	distal	6	no	9.362	9.152	EPSD	COSMIC;CCLE	9.358	Loss
CMGC_MAPK_ERK1_MAPK3_ST	P49815	TSC2	P27361	MAPK3	S1002	S999T	999	Missense	distal	-3	no	9.362	9.332	EPSD	COSMIC	9.358	Loss
CMGC_MAPK_ERK1_MAPK3_ST	P49815	TSC2	P27361	MAPK3	S1002	S999L	999	Missense	distal	-3	no	9.362	9.287	EPSD	COSMIC	9.358	Loss
CMGC_MAPK_ERK1_MAPK3_ST	P49815	TSC2	P27361	MAPK3	S1002	S999P	999	Missense	distal	-3	no	9.362	9.371	EPSD	COSMIC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P49815	TSC2	P27361	MAPK3	S1045	R1044K	1044	Missense	proximal	-1	no	14.972	14.959	EPSD	COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P49815	TSC2	P27361	MAPK3	S1045	A1040T	1040	Missense	distal	-5	no	14.972	15.055	EPSD	COSMIC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P49815	TSC2	P27361	MAPK3	S1045	P1042S	1042	Missense	distal	-3	no	14.972	14.964	EPSD	COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P49815	TSC2	P27361	MAPK3	S1097	S1094L	1094	Missense	distal	-3	no	16.656	16.580	EPSD	COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P49815	TSC2	P27361	MAPK3	S1097	G1099W	1099	Missense	proximal	2	no	16.656	16.600	EPSD	COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P49815	TSC2	P27361	MAPK3	S1097	E1093K	1093	Missense	distal	-4	no	16.656	16.596	EPSD	COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P49815	TSC2	P27361	MAPK3	S1097	S1095I	1095	Missense	proximal	-2	no	16.656	15.894	EPSD	COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P49815	TSC2	P27361	MAPK3	S1097	S1097C	1097	Missense	central	0	yes	16.656	0.000	EPSD	COSMIC	9.358	Loss
CMGC_MAPK_ERK1_MAPK3_ST	P49815	TSC2	P27361	MAPK3	S1147	A1141E	1141	Missense	distal	-6	no	9.148	9.448	EPSD	COSMIC	9.358	Gain
CMGC_MAPK_ERK1_MAPK3_ST	P49815	TSC2	P27361	MAPK3	S1155	Q1148K	1148	Missense	distal	-7	no	14.750	14.751	EPSD	COSMIC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P49815	TSC2	P27361	MAPK3	S1155	R1159Q	1159	Missense	distal	4	no	14.750	14.705	EPSD	COSMIC;GDSC;CCLE	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P49815	TSC2	P27361	MAPK3	S1155	G1151C	1151	Missense	distal	-4	no	14.750	14.550	EPSD	COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P49815	TSC2	P27361	MAPK3	S1155	S1155F	1155	Missense	central	0	yes	14.750	0.000	EPSD	COSMIC	9.358	Loss
CMGC_MAPK_ERK1_MAPK3_ST	P49815	TSC2	P27361	MAPK3	S1155	S1152P	1152	Missense	distal	-3	no	14.750	14.758	EPSD	COSMIC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P49815	TSC2	P27361	MAPK3	S1155	S1152C	1152	Missense	distal	-3	no	14.750	14.572	EPSD	COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P49815	TSC2	P27361	MAPK3	S1304	E1301D	1301	Missense	distal	-3	no	15.828	15.825	EPSD	COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P49815	TSC2	P27361	MAPK3	S1304	E1307K	1307	Missense	distal	3	no	15.828	15.817	EPSD	COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P49815	TSC2	P27361	MAPK3	S1304	P1309S	1309	Missense	distal	5	no	15.828	15.871	EPSD	COSMIC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P49815	TSC2	P27361	MAPK3	S1304	V1298M	1298	Missense	distal	-6	no	15.828	15.736	EPSD	COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P49815	TSC2	P27361	MAPK3	S1304	P1305L	1305	Missense	proximal	1	no	15.828	6.790	EPSD	COSMIC;GDSC	9.358	Loss
CMGC_MAPK_ERK1_MAPK3_ST	P49815	TSC2	P27361	MAPK3	S1304	A1297T	1297	Missense	distal	-7	no	15.828	15.754	EPSD	COSMIC;GDSC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P49815	TSC2	P27361	MAPK3	S1304	G1303R	1303	Missense	proximal	-1	no	15.828	15.852	EPSD	COSMIC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P49815	TSC2	P27361	MAPK3	S1340	S1341F	1341	Missense	proximal	1	no	8.165	11.005	EPSD	COSMIC	9.358	Gain
CMGC_MAPK_ERK1_MAPK3_ST	P49815	TSC2	P27361	MAPK3	S1387	S1383C	1383	Missense	distal	-4	no	9.585	9.347	EPSD	COSMIC	9.358	Loss
CMGC_MAPK_ERK1_MAPK3_ST	P49815	TSC2	P27361	MAPK3	S1387	S1383N	1383	Missense	distal	-4	no	9.585	9.524	EPSD	COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P49815	TSC2	P27361	MAPK3	S1387	S1387L	1387	Missense	central	0	yes	9.585	0.000	EPSD	COSMIC	9.358	Loss
CMGC_MAPK_ERK1_MAPK3_ST	P49815	TSC2	P27361	MAPK3	S1387	S1383R	1383	Missense	distal	-4	no	9.585	9.508	EPSD	COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P49815	TSC2	P27361	MAPK3	S1387	E1390G	1390	Missense	distal	3	no	9.585	9.583	EPSD	COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P49815	TSC2	P27361	MAPK3	S1387	P1389H	1389	Missense	proximal	2	no	9.585	9.571	EPSD	COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P49815	TSC2	P27361	MAPK3	S1387	S1385F	1385	Missense	proximal	-2	no	9.585	8.285	EPSD	COSMIC	9.358	Loss
CMGC_MAPK_ERK1_MAPK3_ST	P49815	TSC2	P27361	MAPK3	S1387	E1390D	1390	Missense	distal	3	no	9.585	9.587	EPSD	COSMIC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P49815	TSC2	P27361	MAPK3	S1388	S1383C	1383	Missense	distal	-5	no	16.488	16.326	EPSD	COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P49815	TSC2	P27361	MAPK3	S1388	S1383N	1383	Missense	distal	-5	no	16.488	16.447	EPSD	COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P49815	TSC2	P27361	MAPK3	S1388	S1387L	1387	Missense	proximal	-1	no	16.488	16.399	EPSD	COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P49815	TSC2	P27361	MAPK3	S1388	S1383R	1383	Missense	distal	-5	no	16.488	16.442	EPSD	COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P49815	TSC2	P27361	MAPK3	S1388	E1390G	1390	Missense	proximal	2	no	16.488	16.479	EPSD	COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P49815	TSC2	P27361	MAPK3	S1388	P1389H	1389	Missense	proximal	1	no	16.488	8.732	EPSD	COSMIC	9.358	Loss
CMGC_MAPK_ERK1_MAPK3_ST	P49815	TSC2	P27361	MAPK3	S1388	S1385F	1385	Missense	distal	-3	no	16.488	16.346	EPSD	COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P49815	TSC2	P27361	MAPK3	S1388	E1390D	1390	Missense	proximal	2	no	16.488	16.485	EPSD	COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P49815	TSC2	P27361	MAPK3	S1411	K1404T	1404	Missense	distal	-7	no	15.709	15.701	EPSD	COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P49815	TSC2	P27361	MAPK3	S1411	R1409Q	1409	Missense	proximal	-2	no	15.709	15.345	EPSD	COSMIC;GDSC;CCLE	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P49815	TSC2	P27361	MAPK3	S1411	G1408V	1408	Missense	distal	-3	no	15.709	15.669	EPSD	COSMIC;GDSC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P49815	TSC2	P27361	MAPK3	S1411	V1407M	1407	Missense	distal	-4	no	15.709	15.681	EPSD	COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P49815	TSC2	P27361	MAPK3	S1411	R1409W	1409	Missense	proximal	-2	no	15.709	13.812	EPSD	COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P49815	TSC2	P27361	MAPK3	S1411	E1413D	1413	Missense	proximal	2	no	15.709	15.706	EPSD	COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P49815	TSC2	P27361	MAPK3	S1411	P1412T	1412	Missense	proximal	1	no	15.709	6.831	EPSD	COSMIC	9.358	Loss
CMGC_MAPK_ERK1_MAPK3_ST	P49815	TSC2	P27361	MAPK3	S1448	S1454N	1454	Missense	distal	6	no	9.785	9.556	EPSD	COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P49815	TSC2	P27361	MAPK3	S1448	P1446S	1446	Missense	proximal	-2	no	9.785	8.709	EPSD	COSMIC	9.358	Loss
CMGC_MAPK_ERK1_MAPK3_ST	P49815	TSC2	P27361	MAPK3	S1448	S1454G	1454	Missense	distal	6	no	9.785	9.553	EPSD	COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P49815	TSC2	P27361	MAPK3	S1448	P1441S	1441	Missense	distal	-7	no	9.785	9.748	EPSD	COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P49815	TSC2	P27361	MAPK3	S1448	L1445M	1445	Missense	distal	-3	no	9.785	9.734	EPSD	COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P49815	TSC2	P27361	MAPK3	S1448	R1451I	1451	Missense	distal	3	no	9.785	9.756	EPSD	COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P49815	TSC2	P27361	MAPK3	S1449	S1454N	1454	Missense	distal	5	no	17.069	16.947	EPSD	COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P49815	TSC2	P27361	MAPK3	S1449	P1446S	1446	Missense	distal	-3	no	17.069	17.061	EPSD	COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P49815	TSC2	P27361	MAPK3	S1449	S1454G	1454	Missense	distal	5	no	17.069	17.005	EPSD	COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P49815	TSC2	P27361	MAPK3	S1449	L1445M	1445	Missense	distal	-4	no	17.069	17.030	EPSD	COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P49815	TSC2	P27361	MAPK3	S1449	R1451I	1451	Missense	proximal	2	no	17.069	17.047	EPSD	COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P49815	TSC2	P27361	MAPK3	S1452	S1454N	1454	Missense	proximal	2	no	17.941	17.924	EPSD	COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P49815	TSC2	P27361	MAPK3	S1452	R1459Q	1459	Missense	distal	7	no	17.941	17.971	EPSD	COSMIC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P49815	TSC2	P27361	MAPK3	S1452	P1446S	1446	Missense	distal	-6	no	17.941	18.026	EPSD	COSMIC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P49815	TSC2	P27361	MAPK3	S1452	S1454G	1454	Missense	proximal	2	no	17.941	17.925	EPSD	COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P49815	TSC2	P27361	MAPK3	S1452	L1445M	1445	Missense	distal	-7	no	17.941	18.002	EPSD	COSMIC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P49815	TSC2	P27361	MAPK3	S1452	R1451I	1451	Missense	proximal	-1	no	17.941	17.852	EPSD	COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P49815	TSC2	P27361	MAPK3	S1464	S1464F	1464	Missense	central	0	yes	9.946	0.000	EPSD	COSMIC	9.358	Loss
CMGC_MAPK_ERK1_MAPK3_ST	P49815	TSC2	P27361	MAPK3	S1464	S1464Y	1464	Missense	central	0	yes	9.946	0.000	EPSD	COSMIC	9.358	Loss
CMGC_MAPK_ERK1_MAPK3_ST	P49815	TSC2	P27361	MAPK3	S1464	Y1461H	1461	Missense	distal	-3	no	9.946	9.978	EPSD	COSMIC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P49815	TSC2	P27361	MAPK3	S1464	R1459Q	1459	Missense	distal	-5	no	9.946	9.939	EPSD	COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P49815	TSC2	P27361	MAPK3	S1464	I1463N	1463	Missense	proximal	-1	no	9.946	10.029	EPSD	COSMIC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P49815	TSC2	P27361	MAPK3	S1464	R1471M	1471	Missense	distal	7	no	9.946	10.227	EPSD	COSMIC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P49815	TSC2	P27361	MAPK3	S1464	R1470H	1470	Missense	distal	6	no	9.946	9.965	EPSD	COSMIC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P49815	TSC2	P27361	MAPK3	S1464	D1465N	1465	Missense	proximal	1	no	9.946	4.459	EPSD	COSMIC	9.358	Loss
CMGC_MAPK_ERK1_MAPK3_ST	P49815	TSC2	P27361	MAPK3	S1464	P1468T	1468	Missense	distal	4	no	9.946	9.882	EPSD	COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P49815	TSC2	P27361	MAPK3	S1464	T1462I	1462	Missense	proximal	-2	no	9.946	9.094	EPSD	COSMIC	9.358	Loss
CMGC_MAPK_ERK1_MAPK3_ST	P49815	TSC2	P27361	MAPK3	S1464	S1464C	1464	Missense	central	0	yes	9.946	0.000	EPSD	COSMIC	9.358	Loss
CMGC_MAPK_ERK1_MAPK3_ST	P49815	TSC2	P27361	MAPK3	S1539	K1544N	1544	Missense	distal	5	no	9.681	9.711	EPSD	COSMIC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P49815	TSC2	P27361	MAPK3	S1539	P1538I	1538	Missense	proximal	-1	no	9.681	9.544	EPSD	COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P49815	TSC2	P27361	MAPK3	S1539	D1535N	1535	Missense	distal	-4	no	9.681	9.655	EPSD	COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P49815	TSC2	P27361	MAPK3	S1539	P1538L	1538	Missense	proximal	-1	no	9.681	9.587	EPSD	COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P49815	TSC2	P27361	MAPK3	S1539	Y1540D	1540	Missense	proximal	1	no	9.681	8.128	EPSD	COSMIC	9.358	Loss
CMGC_MAPK_ERK1_MAPK3_ST	P49815	TSC2	P27361	MAPK3	S1539	D1541A	1541	Missense	proximal	2	no	9.681	9.654	EPSD	COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P49815	TSC2	P27361	MAPK3	S1539	Q1536H	1536	Missense	distal	-3	no	9.681	9.695	EPSD	COSMIC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P49815	TSC2	P27361	MAPK3	S1772	S1774T	1774	Missense	proximal	2	no	10.774	10.763	EPSD	COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P49815	TSC2	P27361	MAPK3	S1772	P1770S	1770	Missense	proximal	-2	no	10.774	9.698	EPSD	COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P49815	TSC2	P27361	MAPK3	S1772	P1771L	1771	Missense	proximal	-1	no	10.774	10.679	EPSD	COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P49815	TSC2	P27361	MAPK3	S1772	A1778G	1778	Missense	distal	6	no	10.774	11.067	EPSD	COSMIC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P49815	TSC2	P27361	MAPK3	S1772	A1776G	1776	Missense	distal	4	no	10.774	10.944	EPSD	COSMIC;GDSC;CCLE	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P49815	TSC2	P27361	MAPK3	T1780	P1781L	1781	Missense	proximal	1	no	16.371	7.333	EPSD	COSMIC	9.358	Loss
CMGC_MAPK_ERK1_MAPK3_ST	P49815	TSC2	P27361	MAPK3	T1780	A1782V	1782	Missense	proximal	2	no	16.371	16.385	EPSD	COSMIC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P49815	TSC2	P27361	MAPK3	T1780	S1774T	1774	Missense	distal	-6	no	16.371	16.203	EPSD	COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P49815	TSC2	P27361	MAPK3	T1780	G1787S	1787	Missense	distal	7	no	16.371	16.232	EPSD	COSMIC;GDSC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P49815	TSC2	P27361	MAPK3	T1780	P1786S	1786	Missense	distal	6	no	16.371	16.501	EPSD	COSMIC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P49815	TSC2	P27361	MAPK3	T1780	A1778G	1778	Missense	proximal	-2	no	16.371	16.606	EPSD	COSMIC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P49815	TSC2	P27361	MAPK3	T1780	P1786R	1786	Missense	distal	6	no	16.371	16.259	EPSD	COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P49815	TSC2	P27361	MAPK3	T1780	P1784S	1784	Missense	distal	4	no	16.371	16.420	EPSD	COSMIC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P49815	TSC2	P27361	MAPK3	T1780	A1776G	1776	Missense	distal	-4	no	16.371	16.465	EPSD	COSMIC;GDSC;CCLE	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P49815	TSC2	P27361	MAPK3	T1780	P1784R	1784	Missense	distal	4	no	16.371	16.274	EPSD	COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P49815	TSC2	P27361	MAPK3	T1785	P1781L	1781	Missense	distal	-4	no	18.431	18.318	EPSD	COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P49815	TSC2	P27361	MAPK3	T1785	A1782V	1782	Missense	distal	-3	no	18.431	18.450	EPSD	COSMIC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P49815	TSC2	P27361	MAPK3	T1785	G1787S	1787	Missense	proximal	2	no	18.431	18.448	EPSD	COSMIC;GDSC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P49815	TSC2	P27361	MAPK3	T1785	P1786S	1786	Missense	proximal	1	no	18.431	9.377	EPSD	COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P49815	TSC2	P27361	MAPK3	T1785	G1791S	1791	Missense	distal	6	no	18.431	18.663	EPSD	COSMIC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P49815	TSC2	P27361	MAPK3	T1785	V1790M	1790	Missense	distal	5	no	18.431	18.307	EPSD	COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P49815	TSC2	P27361	MAPK3	T1785	A1778G	1778	Missense	distal	-7	no	18.431	18.319	EPSD	COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P49815	TSC2	P27361	MAPK3	T1785	P1786R	1786	Missense	proximal	1	no	18.431	8.930	EPSD	COSMIC	9.358	Loss
CMGC_MAPK_ERK1_MAPK3_ST	P49815	TSC2	P27361	MAPK3	T1785	P1784S	1784	Missense	proximal	-1	no	18.431	18.425	EPSD	COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P49815	TSC2	P27361	MAPK3	T1785	P1784R	1784	Missense	proximal	-1	no	18.431	18.383	EPSD	COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P49815	TSC2	P27361	MAPK3	S1798	R1795H	1795	Missense	distal	-3	no	9.592	9.599	EPSD	COSMIC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P49815	TSC2	P27361	MAPK3	S1798	R1793Q	1793	Missense	distal	-5	no	9.592	9.585	EPSD	COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P49815	TSC2	P27361	MAPK3	S1798	R1795C	1795	Missense	distal	-3	no	9.592	9.452	EPSD	COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P49815	TSC2	P27361	MAPK3	S1798	R1793W	1793	Missense	distal	-5	no	9.592	9.439	EPSD	COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P49815	TSC2	P27361	MAPK3	S1798	G1791S	1791	Missense	distal	-7	no	9.592	9.555	EPSD	COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P49815	TSC2	P27361	MAPK3	S1798	T1804I	1804	Missense	distal	6	no	9.592	9.178	EPSD	COSMIC	9.358	Loss
CMGC_MAPK_ERK1_MAPK3_ST	P49815	TSC2	P27361	MAPK3	S1798	R1793H	1793	Missense	distal	-5	no	9.592	9.602	EPSD	COSMIC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P49815	TSC2	P27361	MAPK3	S1798	R1793C	1793	Missense	distal	-5	no	9.592	9.476	EPSD	COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P10415	BCL2	P27361	MAPK3	T56	F49C	49	Missense	distal	-7	no	15.980	16.030	EPSD;PhosphoSitePlus	COSMIC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P10415	BCL2	P27361	MAPK3	T56	S51Y	51	Missense	distal	-5	no	15.980	15.916	EPSD;PhosphoSitePlus	COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P10415	BCL2	P27361	MAPK3	T56	P57S	57	Missense	proximal	1	no	15.980	6.926	EPSD;PhosphoSitePlus	COSMIC	9.358	Loss
CMGC_MAPK_ERK1_MAPK3_ST	P10415	BCL2	P27361	MAPK3	T56	F49S	49	Missense	distal	-7	no	15.980	15.761	EPSD;PhosphoSitePlus	COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P10415	BCL2	P27361	MAPK3	T56	H58L	58	Missense	proximal	2	no	15.980	15.972	EPSD;PhosphoSitePlus	COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P10415	BCL2	P27361	MAPK3	T56	Q52P	52	Missense	distal	-4	no	15.980	16.019	EPSD;PhosphoSitePlus	COSMIC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P10415	BCL2	P27361	MAPK3	T56	S51P	51	Missense	distal	-5	no	15.980	15.975	EPSD;PhosphoSitePlus	COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P10415	BCL2	P27361	MAPK3	T56	S50P	50	Missense	distal	-6	no	15.980	15.895	EPSD;PhosphoSitePlus	COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P10415	BCL2	P27361	MAPK3	T56	H58R	58	Missense	proximal	2	no	15.980	15.983	EPSD;PhosphoSitePlus	COSMIC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P10415	BCL2	P27361	MAPK3	T56	A60G	60	Missense	distal	4	no	15.980	16.150	EPSD;PhosphoSitePlus	COSMIC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P10415	BCL2	P27361	MAPK3	T56	P57L	57	Missense	proximal	1	no	15.980	6.942	EPSD;PhosphoSitePlus	COSMIC	9.358	Loss
CMGC_MAPK_ERK1_MAPK3_ST	P10415	BCL2	P27361	MAPK3	T56	A60D	60	Missense	distal	4	no	15.980	16.191	EPSD;PhosphoSitePlus	COSMIC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P10415	BCL2	P27361	MAPK3	T56	Q52H	52	Missense	distal	-4	no	15.980	15.984	EPSD;PhosphoSitePlus	COSMIC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P10415	BCL2	P27361	MAPK3	T56	P57A	57	Missense	proximal	1	no	15.980	6.740	EPSD;PhosphoSitePlus	COSMIC	9.358	Loss
CMGC_MAPK_ERK1_MAPK3_ST	P10415	BCL2	P27361	MAPK3	S70	T74N	74	Missense	distal	4	no	17.225	17.192	EPSD	COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P10415	BCL2	P27361	MAPK3	S70	T69A	69	Missense	proximal	-1	no	17.225	17.122	EPSD	COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P10415	BCL2	P27361	MAPK3	S70	A67V	67	Missense	distal	-3	no	17.225	17.245	EPSD	COSMIC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P10415	BCL2	P27361	MAPK3	S70	P65S	65	Missense	distal	-5	no	17.225	17.230	EPSD	COSMIC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P10415	BCL2	P27361	MAPK3	S70	A76T	76	Missense	distal	6	no	17.225	17.596	EPSD	COSMIC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P10415	BCL2	P27361	MAPK3	S70	A77V	77	Missense	distal	7	no	17.225	17.197	EPSD	COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P10415	BCL2	P27361	MAPK3	S70	P71S	71	Missense	proximal	1	no	17.225	8.172	EPSD	COSMIC	9.358	Loss
CMGC_MAPK_ERK1_MAPK3_ST	P10415	BCL2	P27361	MAPK3	S70	D64G	64	Missense	distal	-6	no	17.225	17.224	EPSD	COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P10415	BCL2	P27361	MAPK3	S70	A76S	76	Missense	distal	6	no	17.225	17.751	EPSD	COSMIC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P10415	BCL2	P27361	MAPK3	S70	T74A	74	Missense	distal	4	no	17.225	17.007	EPSD	COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P10415	BCL2	P27361	MAPK3	S70	T74I	74	Missense	distal	4	no	17.225	16.997	EPSD	COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P10415	BCL2	P27361	MAPK3	S70	T69P	69	Missense	proximal	-1	no	17.225	17.262	EPSD	COSMIC;CCLE	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P10415	BCL2	P27361	MAPK3	S70	V66I	66	Missense	distal	-4	no	17.225	17.218	EPSD	COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P10415	BCL2	P27361	MAPK3	S70	P65Q	65	Missense	distal	-5	no	17.225	17.177	EPSD	COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P10415	BCL2	P27361	MAPK3	T74	T74N	74	Missense	central	0	yes	17.429	0.000	PhosphoSitePlus;EPSD	COSMIC	9.358	Loss
CMGC_MAPK_ERK1_MAPK3_ST	P10415	BCL2	P27361	MAPK3	T74	T69A	69	Missense	distal	-5	no	17.429	17.346	PhosphoSitePlus;EPSD	COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P10415	BCL2	P27361	MAPK3	T74	A76T	76	Missense	proximal	2	no	17.429	17.457	PhosphoSitePlus;EPSD	COSMIC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P10415	BCL2	P27361	MAPK3	T74	A77V	77	Missense	distal	3	no	17.429	17.436	PhosphoSitePlus;EPSD	COSMIC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P10415	BCL2	P27361	MAPK3	T74	P71S	71	Missense	distal	-3	no	17.429	17.421	PhosphoSitePlus;EPSD	COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P10415	BCL2	P27361	MAPK3	T74	A76S	76	Missense	proximal	2	no	17.429	17.468	PhosphoSitePlus;EPSD	COSMIC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P10415	BCL2	P27361	MAPK3	T74	T74A	74	Missense	central	0	yes	17.429	0.000	PhosphoSitePlus;EPSD	COSMIC	9.358	Loss
CMGC_MAPK_ERK1_MAPK3_ST	P10415	BCL2	P27361	MAPK3	T74	A80V	80	Missense	distal	6	no	17.429	17.517	PhosphoSitePlus;EPSD	COSMIC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P10415	BCL2	P27361	MAPK3	T74	T74I	74	Missense	central	0	yes	17.429	0.000	PhosphoSitePlus;EPSD	COSMIC	9.358	Loss
CMGC_MAPK_ERK1_MAPK3_ST	P10415	BCL2	P27361	MAPK3	T74	T69P	69	Missense	distal	-5	no	17.429	17.440	PhosphoSitePlus;EPSD	COSMIC;CCLE	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P10415	BCL2	P27361	MAPK3	S87	L86F	86	Missense	proximal	-1	no	13.964	13.848	EPSD;PhosphoSitePlus	COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P10415	BCL2	P27361	MAPK3	S87	A85V	85	Missense	proximal	-2	no	13.964	14.660	EPSD;PhosphoSitePlus	COSMIC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P10415	BCL2	P27361	MAPK3	S87	P91S	91	Missense	distal	4	no	13.964	14.013	EPSD;PhosphoSitePlus	COSMIC;GDSC;CCLE	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P10415	BCL2	P27361	MAPK3	S87	G83E	83	Missense	distal	-4	no	13.964	13.978	EPSD;PhosphoSitePlus	COSMIC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P10415	BCL2	P27361	MAPK3	S87	P91A	91	Missense	distal	4	no	13.964	13.682	EPSD;PhosphoSitePlus	COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P10415	BCL2	P27361	MAPK3	S87	P90T	90	Missense	distal	3	no	13.964	13.946	EPSD;PhosphoSitePlus	COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P10415	BCL2	P27361	MAPK3	S87	H94Y	94	Missense	distal	7	no	13.964	14.082	EPSD;PhosphoSitePlus	COSMIC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P10415	BCL2	P27361	MAPK3	S87	A85T	85	Missense	proximal	-2	no	13.964	15.329	EPSD;PhosphoSitePlus	COSMIC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P10415	BCL2	P27361	MAPK3	S87	V93L	93	Missense	distal	6	no	13.964	14.046	EPSD;PhosphoSitePlus	COSMIC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P10415	BCL2	P27361	MAPK3	S87	P91L	91	Missense	distal	4	no	13.964	13.809	EPSD;PhosphoSitePlus	COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P10415	BCL2	P27361	MAPK3	S87	S87N	87	Missense	central	0	yes	13.964	0.000	EPSD;PhosphoSitePlus	COSMIC	9.358	Loss
CMGC_MAPK_ERK1_MAPK3_ST	P10415	BCL2	P27361	MAPK3	S87	A80V	80	Missense	distal	-7	no	13.964	13.963	EPSD;PhosphoSitePlus	COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q9NQ66	PLCB1	P27361	MAPK3	T39	P40S	40	Missense	proximal	1	no	15.226	6.172	EPSD	COSMIC	9.358	Loss
CMGC_MAPK_ERK1_MAPK3_ST	Q9NQ66	PLCB1	P27361	MAPK3	S387	I386T	386	Missense	proximal	-1	no	9.702	9.803	EPSD	COSMIC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q9NQ66	PLCB1	P27361	MAPK3	S387	K389M	389	Missense	proximal	2	no	9.702	9.675	EPSD	COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q9NQ66	PLCB1	P27361	MAPK3	S410	S403L	403	Missense	distal	-7	no	9.264	9.408	EPSD	COSMIC	9.358	Gain
CMGC_MAPK_ERK1_MAPK3_ST	Q9NQ66	PLCB1	P27361	MAPK3	S417	N413K	413	Missense	distal	-4	no	16.108	16.085	EPSD	COSMIC;GDSC;CCLE	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q9NQ66	PLCB1	P27361	MAPK3	S417	D416V	416	Missense	proximal	-1	no	16.108	16.071	EPSD	COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q9NQ66	PLCB1	P27361	MAPK3	S417	P418S	418	Missense	proximal	1	no	16.108	7.055	EPSD	COSMIC	9.358	Loss
CMGC_MAPK_ERK1_MAPK3_ST	Q9NQ66	PLCB1	P27361	MAPK3	S417	K423E	423	Missense	distal	6	no	16.108	16.184	EPSD	COSMIC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q9NQ66	PLCB1	P27361	MAPK3	S417	D416N	416	Missense	proximal	-1	no	16.108	16.106	EPSD	COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q9NQ66	PLCB1	P27361	MAPK3	S454	E447K	447	Missense	distal	-7	no	15.399	15.450	EPSD	COSMIC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q9NQ66	PLCB1	P27361	MAPK3	S454	M456I	456	Missense	proximal	2	no	15.399	15.407	EPSD	COSMIC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q9NQ66	PLCB1	P27361	MAPK3	S454	Y460C	460	Missense	distal	6	no	15.399	14.914	EPSD	COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q9NQ66	PLCB1	P27361	MAPK3	S454	K461I	461	Missense	distal	7	no	15.399	15.622	EPSD	COSMIC;GDSC;CCLE	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q9NQ66	PLCB1	P27361	MAPK3	S501	G503E	503	Missense	proximal	2	no	17.376	17.384	EPSD	COSMIC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q9NQ66	PLCB1	P27361	MAPK3	S582	G575R	575	Missense	distal	-7	no	17.743	17.788	EPSD	COSMIC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q9NQ66	PLCB1	P27361	MAPK3	S582	G575E	575	Missense	distal	-7	no	17.743	17.737	EPSD	COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q9NQ66	PLCB1	P27361	MAPK3	S582	Y589S	589	Missense	distal	7	no	17.743	17.488	EPSD	COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q9NQ66	PLCB1	P27361	MAPK3	S582	P583A	583	Missense	proximal	1	no	17.743	8.503	EPSD	COSMIC	9.358	Loss
CMGC_MAPK_ERK1_MAPK3_ST	Q9NQ66	PLCB1	P27361	MAPK3	S582	E585K	585	Missense	distal	3	no	17.743	17.732	EPSD	COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q9NQ66	PLCB1	P27361	MAPK3	T871	T869I	869	Missense	proximal	-2	no	15.473	14.620	EPSD	COSMIC;CCLE	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q9NQ66	PLCB1	P27361	MAPK3	T871	H866R	866	Missense	distal	-5	no	15.473	15.463	EPSD	COSMIC;CCLE	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q9NQ66	PLCB1	P27361	MAPK3	T871	Q877K	877	Missense	distal	6	no	15.473	15.576	EPSD	COSMIC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q9NQ66	PLCB1	P27361	MAPK3	S876	T869I	869	Missense	distal	-7	no	9.885	10.000	EPSD	COSMIC;CCLE	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q9NQ66	PLCB1	P27361	MAPK3	S876	Q877K	877	Missense	proximal	1	no	9.885	0.676	EPSD	COSMIC	9.358	Loss
CMGC_MAPK_ERK1_MAPK3_ST	Q9NQ66	PLCB1	P27361	MAPK3	S876	Q882K	882	Missense	distal	6	no	9.885	9.989	EPSD	COSMIC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q9NQ66	PLCB1	P27361	MAPK3	S982	D984H	984	Missense	proximal	2	no	17.827	17.823	PhosphoSitePlus	COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q9NQ66	PLCB1	P27361	MAPK3	S982	E979K	979	Missense	distal	-3	no	17.827	17.796	PhosphoSitePlus	COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q9NQ66	PLCB1	P27361	MAPK3	T1197	E1202K	1202	Missense	distal	5	no	20.818	20.690	EPSD	COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q9NQ66	PLCB1	P27361	MAPK3	T1197	P1198L	1198	Missense	proximal	1	no	20.818	11.780	EPSD	COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q9NQ66	PLCB1	P27361	MAPK3	T1197	P1190N	1190	Missense	distal	-7	no	20.818	20.848	EPSD	COSMIC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q9NQ66	PLCB1	P27361	MAPK3	T1197	S1199Y	1199	Missense	proximal	2	no	20.818	20.796	EPSD	COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q9NQ66	PLCB1	P27361	MAPK3	S1199	E1202K	1202	Missense	distal	3	no	10.765	10.754	EPSD	COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q9NQ66	PLCB1	P27361	MAPK3	S1199	P1198L	1198	Missense	proximal	-1	no	10.765	10.670	EPSD	COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q9NQ66	PLCB1	P27361	MAPK3	S1199	S1199Y	1199	Missense	central	0	yes	10.765	0.000	EPSD	COSMIC	9.358	Loss
CMGC_MAPK_ERK1_MAPK3_ST	Q9NQ66	PLCB1	P27361	MAPK3	S1200	E1202K	1202	Missense	proximal	2	no	12.511	12.503	EPSD	COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q9NQ66	PLCB1	P27361	MAPK3	S1200	P1198L	1198	Missense	proximal	-2	no	12.511	11.126	EPSD	COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q9NQ66	PLCB1	P27361	MAPK3	S1200	S1199Y	1199	Missense	proximal	-1	no	12.511	12.434	EPSD	COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q13950	RUNX2	P27361	MAPK3	S24	P29H	29	Missense	distal	5	no	10.701	10.636	EPSD;PhosphoSitePlus	COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q13950	RUNX2	P27361	MAPK3	S28	P29H	29	Missense	proximal	1	no	16.754	8.998	EPSD;PhosphoSitePlus	COSMIC	9.358	Loss
CMGC_MAPK_ERK1_MAPK3_ST	Q13950	RUNX2	P27361	MAPK3	S43	P36S	36	Missense	distal	-7	no	17.125	17.087	EPSD;PhosphoSitePlus	COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q13950	RUNX2	P27361	MAPK3	S118	D117N	117	Missense	proximal	-1	no	17.239	17.237	EPSD	COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q13950	RUNX2	P27361	MAPK3	S118	L122M	122	Missense	distal	4	no	17.239	17.064	EPSD	COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q13950	RUNX2	P27361	MAPK3	S275	P274S	274	Missense	proximal	-1	no	15.279	15.273	EPSD;PhosphoSitePlus	COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q13950	RUNX2	P27361	MAPK3	S275	A273G	273	Missense	proximal	-2	no	15.279	15.513	EPSD;PhosphoSitePlus	COSMIC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q13950	RUNX2	P27361	MAPK3	S294	S293P	293	Missense	proximal	-1	no	14.564	14.570	EPSD;PhosphoSitePlus	COSMIC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q13950	RUNX2	P27361	MAPK3	S294	S298F	298	Missense	distal	4	no	14.564	14.149	EPSD;PhosphoSitePlus	COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q13950	RUNX2	P27361	MAPK3	S298	S293P	293	Missense	distal	-5	no	9.480	9.475	EPSD	COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q13950	RUNX2	P27361	MAPK3	S298	S305F	305	Missense	distal	7	no	9.480	9.971	EPSD	COSMIC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q13950	RUNX2	P27361	MAPK3	S298	S305T	305	Missense	distal	7	no	9.480	9.599	EPSD	COSMIC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q13950	RUNX2	P27361	MAPK3	S298	S298F	298	Missense	central	0	yes	9.480	0.000	EPSD	COSMIC	9.358	Loss
CMGC_MAPK_ERK1_MAPK3_ST	Q13950	RUNX2	P27361	MAPK3	S302	S305F	305	Missense	distal	3	no	10.485	10.420	EPSD	COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q13950	RUNX2	P27361	MAPK3	S302	S305T	305	Missense	distal	3	no	10.485	10.471	EPSD	COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q13950	RUNX2	P27361	MAPK3	S302	S308F	308	Missense	distal	6	no	10.485	9.771	EPSD	COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q13950	RUNX2	P27361	MAPK3	S302	S298F	298	Missense	distal	-4	no	10.485	10.296	EPSD	COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q13950	RUNX2	P27361	MAPK3	S305	S305F	305	Missense	central	0	yes	10.376	0.000	EPSD	COSMIC	9.358	Loss
CMGC_MAPK_ERK1_MAPK3_ST	Q13950	RUNX2	P27361	MAPK3	S305	S308F	308	Missense	distal	3	no	10.376	10.311	EPSD	COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q13950	RUNX2	P27361	MAPK3	S305	S298F	298	Missense	distal	-7	no	10.376	10.595	EPSD	COSMIC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q13950	RUNX2	P27361	MAPK3	S312	S305F	305	Missense	distal	-7	no	13.545	13.764	PhosphoSitePlus;EPSD	COSMIC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q13950	RUNX2	P27361	MAPK3	S312	S305T	305	Missense	distal	-7	no	13.545	13.622	PhosphoSitePlus;EPSD	COSMIC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q13950	RUNX2	P27361	MAPK3	S312	S308F	308	Missense	distal	-4	no	13.545	13.356	PhosphoSitePlus;EPSD	COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q13950	RUNX2	P27361	MAPK3	T319	R325P	325	Missense	distal	6	no	14.702	14.814	EPSD	COSMIC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q13950	RUNX2	P27361	MAPK3	T319	S322F	322	Missense	distal	3	no	14.702	14.638	EPSD	COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q13950	RUNX2	P27361	MAPK3	T319	P320T	320	Missense	proximal	1	no	14.702	5.825	EPSD	COSMIC	9.358	Loss
CMGC_MAPK_ERK1_MAPK3_ST	Q13950	RUNX2	P27361	MAPK3	S322	R325P	325	Missense	distal	3	no	10.246	10.272	EPSD	COSMIC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q13950	RUNX2	P27361	MAPK3	S322	S322F	322	Missense	central	0	yes	10.246	0.000	EPSD	COSMIC	9.358	Loss
CMGC_MAPK_ERK1_MAPK3_ST	Q13950	RUNX2	P27361	MAPK3	S322	T327N	327	Missense	distal	5	no	10.246	10.259	EPSD	COSMIC;CCLE	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q13950	RUNX2	P27361	MAPK3	S322	P320T	320	Missense	proximal	-2	no	10.246	9.260	EPSD	COSMIC	9.358	Loss
CMGC_MAPK_ERK1_MAPK3_ST	Q13950	RUNX2	P27361	MAPK3	T324	R325P	325	Missense	proximal	1	no	5.981	15.482	EPSD	COSMIC	9.358	Gain
CMGC_MAPK_ERK1_MAPK3_ST	Q13950	RUNX2	P27361	MAPK3	S340	R338C	338	Missense	proximal	-2	no	10.197	8.081	EPSD;PhosphoSitePlus	COSMIC	9.358	Loss
CMGC_MAPK_ERK1_MAPK3_ST	Q13950	RUNX2	P27361	MAPK3	S340	A345D	345	Missense	distal	5	no	10.197	10.410	EPSD;PhosphoSitePlus	COSMIC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q13950	RUNX2	P27361	MAPK3	S465	S467F	467	Missense	proximal	2	no	15.290	15.240	EPSD	COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q13950	RUNX2	P27361	MAPK3	S465	S467Y	467	Missense	proximal	2	no	15.290	15.269	EPSD	COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q13950	RUNX2	P27361	MAPK3	S465	P472T	472	Missense	distal	7	no	15.290	15.331	EPSD	COSMIC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q13950	RUNX2	P27361	MAPK3	S465	G462E	462	Missense	distal	-3	no	15.290	15.303	EPSD	COSMIC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q13950	RUNX2	P27361	MAPK3	S465	P466H	466	Missense	proximal	1	no	15.290	7.535	EPSD	COSMIC	9.358	Loss
CMGC_MAPK_ERK1_MAPK3_ST	Q13950	RUNX2	P27361	MAPK3	S465	P466L	466	Missense	proximal	1	no	15.290	6.252	EPSD	COSMIC	9.358	Loss
CMGC_MAPK_ERK1_MAPK3_ST	Q13950	RUNX2	P27361	MAPK3	S499	D492N	492	Missense	distal	-7	no	11.318	11.343	EPSD	COSMIC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q13950	RUNX2	P27361	MAPK3	S499	S503F	503	Missense	distal	4	no	11.318	10.904	EPSD	COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q13950	RUNX2	P27361	MAPK3	S499	A496T	496	Missense	distal	-3	no	11.318	11.380	EPSD	COSMIC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q13950	RUNX2	P27361	MAPK3	S501	S503F	503	Missense	proximal	2	no	11.548	11.498	EPSD	COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q13950	RUNX2	P27361	MAPK3	S501	A496T	496	Missense	distal	-5	no	11.548	11.632	EPSD	COSMIC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q13950	RUNX2	P27361	MAPK3	S502	S503F	503	Missense	proximal	1	no	12.013	14.853	EPSD	COSMIC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q13950	RUNX2	P27361	MAPK3	S502	A496T	496	Missense	distal	-6	no	12.013	12.161	EPSD	COSMIC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q13950	RUNX2	P27361	MAPK3	S503	S503F	503	Missense	central	0	yes	20.559	0.000	EPSD;PhosphoSitePlus	COSMIC	9.358	Loss
CMGC_MAPK_ERK1_MAPK3_ST	Q13950	RUNX2	P27361	MAPK3	S503	A496T	496	Missense	distal	-7	no	20.559	20.486	EPSD;PhosphoSitePlus	COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P17655	CAPN2	P27361	MAPK3	S50	P52Q	52	Missense	proximal	2	no	11.625	11.605	PhosphoSitePlus	COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P17655	CAPN2	P27361	MAPK3	T344	R337C	337	Missense	distal	-7	no	14.586	14.773	EPSD	COSMIC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P17655	CAPN2	P27361	MAPK3	T406	T406P	406	Missense	central	0	yes	9.557	0.000	EPSD	COSMIC	9.358	Loss
CMGC_MAPK_ERK1_MAPK3_ST	P17655	CAPN2	P27361	MAPK3	T464	R461S	461	Missense	distal	-3	no	9.340	9.378	EPSD	COSMIC	9.358	Gain
CMGC_MAPK_ERK1_MAPK3_ST	P28324	ELK4	P27361	MAPK3	S137	R138H	138	Missense	proximal	1	no	8.483	10.227	EPSD	COSMIC	9.358	Gain
CMGC_MAPK_ERK1_MAPK3_ST	P28324	ELK4	P27361	MAPK3	S230	T227I	227	Missense	distal	-3	no	17.506	17.425	EPSD	COSMIC;GDSC;CCLE	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P28324	ELK4	P27361	MAPK3	S230	Q223K	223	Missense	distal	-7	no	17.506	17.508	EPSD	COSMIC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P28324	ELK4	P27361	MAPK3	S230	S230F	230	Missense	central	0	yes	17.506	0.000	EPSD	COSMIC	9.358	Loss
CMGC_MAPK_ERK1_MAPK3_ST	P28324	ELK4	P27361	MAPK3	S381	P382H	382	Missense	proximal	1	no	16.534	8.778	EPSD;PhosphoSitePlus	COSMIC	9.358	Loss
CMGC_MAPK_ERK1_MAPK3_ST	P28324	ELK4	P27361	MAPK3	S381	L380V	380	Missense	proximal	-1	no	16.534	16.539	EPSD;PhosphoSitePlus	COSMIC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P28324	ELK4	P27361	MAPK3	S387	P382H	382	Missense	distal	-5	no	17.434	17.403	PhosphoSitePlus;EPSD	COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P28324	ELK4	P27361	MAPK3	S387	L380V	380	Missense	distal	-7	no	17.434	17.438	PhosphoSitePlus;EPSD	COSMIC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P28324	ELK4	P27361	MAPK3	T420	D427N	427	Missense	distal	7	no	18.224	18.283	EPSD	COSMIC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P28324	ELK4	P27361	MAPK3	T420	F424L	424	Missense	distal	4	no	18.224	18.435	EPSD	COSMIC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P28324	ELK4	P27361	MAPK3	T420	G414W	414	Missense	distal	-6	no	18.224	17.604	EPSD	COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P28324	ELK4	P27361	MAPK3	T420	P421F	421	Missense	proximal	1	no	18.224	12.010	EPSD	COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P28324	ELK4	P27361	MAPK3	S425	K430N	430	Missense	distal	5	no	22.250	22.280	EPSD	COSMIC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P28324	ELK4	P27361	MAPK3	S425	D427N	427	Missense	proximal	2	no	22.250	22.244	EPSD	COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P28324	ELK4	P27361	MAPK3	S425	F424L	424	Missense	proximal	-1	no	22.250	22.365	EPSD	COSMIC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P28324	ELK4	P27361	MAPK3	S425	L428P	428	Missense	distal	3	no	22.250	22.287	EPSD	COSMIC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P28324	ELK4	P27361	MAPK3	S425	P421F	421	Missense	distal	-4	no	22.250	22.088	EPSD	COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	O75030	MITF	P27361	MAPK3	S175	V168F	168	Missense	distal	-7	no	10.252	10.322	EPSD	COSMIC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	O75030	MITF	P27361	MAPK3	S175	A177V	177	Missense	proximal	2	no	10.252	10.265	EPSD	COSMIC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	O75030	MITF	P27361	MAPK3	S175	N179I	179	Missense	distal	4	no	10.252	10.058	EPSD	COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	O75030	MITF	P27361	MAPK3	S175	P170L	170	Missense	distal	-5	no	10.252	10.198	EPSD	COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	O75030	MITF	P27361	MAPK3	S175	P170S	170	Missense	distal	-5	no	10.252	10.257	EPSD	COSMIC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	O75030	MITF	P27361	MAPK3	S180	A177V	177	Missense	distal	-3	no	20.188	20.207	EPSD	COSMIC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	O75030	MITF	P27361	MAPK3	S180	N179I	179	Missense	proximal	-1	no	20.188	20.105	EPSD	COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	O75030	MITF	P27361	MAPK3	S216	R217H	217	Missense	proximal	1	no	8.475	10.220	EPSD	COSMIC	9.358	Gain
CMGC_MAPK_ERK1_MAPK3_ST	O75030	MITF	P27361	MAPK3	S216	R217W	217	Missense	proximal	1	no	8.475	10.072	EPSD	COSMIC	9.358	Gain
CMGC_MAPK_ERK1_MAPK3_ST	O75030	MITF	P27361	MAPK3	S414	R420Q	420	Missense	distal	6	no	16.855	16.786	EPSD	COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	O75030	MITF	P27361	MAPK3	S414	C413F	413	Missense	proximal	-1	no	16.855	16.878	EPSD	COSMIC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	O75030	MITF	P27361	MAPK3	S491	V493I	493	Missense	proximal	2	no	15.940	15.930	EPSD	COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	O75030	MITF	P27361	MAPK3	S491	D487N	487	Missense	distal	-4	no	15.940	15.914	EPSD	COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	O75030	MITF	P27361	MAPK3	S491	T489N	489	Missense	proximal	-2	no	15.940	14.905	EPSD	COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	O75030	MITF	P27361	MAPK3	S501	A507T	507	Missense	distal	6	no	8.994	9.365	EPSD	COSMIC	9.358	Gain
CMGC_MAPK_ERK1_MAPK3_ST	O75030	MITF	P27361	MAPK3	S504	S504F	504	Missense	central	0	yes	19.521	0.000	EPSD	COSMIC	9.358	Loss
CMGC_MAPK_ERK1_MAPK3_ST	O75030	MITF	P27361	MAPK3	S504	A507T	507	Missense	distal	3	no	19.521	19.552	EPSD	COSMIC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	O75030	MITF	P27361	MAPK3	S504	S511I	511	Missense	distal	7	no	19.521	19.920	EPSD	COSMIC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	O75030	MITF	P27361	MAPK3	T510	S512I	512	Missense	proximal	2	no	10.527	10.492	EPSD	COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	O75030	MITF	P27361	MAPK3	T510	S504F	504	Missense	distal	-6	no	10.527	10.060	EPSD	COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	O75030	MITF	P27361	MAPK3	T510	A507T	507	Missense	distal	-3	no	10.527	10.589	EPSD	COSMIC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	O75030	MITF	P27361	MAPK3	T510	R513W	513	Missense	distal	3	no	10.527	10.449	EPSD	COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	O75030	MITF	P27361	MAPK3	T510	S511I	511	Missense	proximal	1	no	10.527	10.073	EPSD	COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	O75030	MITF	P27361	MAPK3	S511	S512I	512	Missense	proximal	1	no	9.833	9.379	EPSD	COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	O75030	MITF	P27361	MAPK3	S511	S504F	504	Missense	distal	-7	no	9.833	10.052	EPSD	COSMIC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	O75030	MITF	P27361	MAPK3	S511	A507T	507	Missense	distal	-4	no	9.833	9.906	EPSD	COSMIC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	O75030	MITF	P27361	MAPK3	S511	R513W	513	Missense	proximal	2	no	9.833	9.772	EPSD	COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	O75030	MITF	P27361	MAPK3	S511	S518I	518	Missense	distal	7	no	9.833	10.231	EPSD	COSMIC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	O75030	MITF	P27361	MAPK3	S511	S511I	511	Missense	central	0	yes	9.833	0.000	EPSD	COSMIC	9.358	Loss
CMGC_MAPK_ERK1_MAPK3_ST	O75030	MITF	P27361	MAPK3	S512	S512I	512	Missense	central	0	yes	10.216	0.000	EPSD	COSMIC	9.358	Loss
CMGC_MAPK_ERK1_MAPK3_ST	O75030	MITF	P27361	MAPK3	S512	A507T	507	Missense	distal	-5	no	10.216	10.299	EPSD	COSMIC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	O75030	MITF	P27361	MAPK3	S512	R513W	513	Missense	proximal	1	no	10.216	11.813	EPSD	COSMIC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	O75030	MITF	P27361	MAPK3	S512	S518I	518	Missense	distal	6	no	10.216	9.646	EPSD	COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	O75030	MITF	P27361	MAPK3	S512	S511I	511	Missense	proximal	-1	no	10.216	10.085	EPSD	COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	O75030	MITF	P27361	MAPK3	S515	S512I	512	Missense	distal	-3	no	10.739	10.628	EPSD	COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	O75030	MITF	P27361	MAPK3	S515	R513W	513	Missense	proximal	-2	no	10.739	8.843	EPSD	COSMIC	9.358	Loss
CMGC_MAPK_ERK1_MAPK3_ST	O75030	MITF	P27361	MAPK3	S515	T522M	522	Missense	distal	7	no	10.739	11.071	EPSD	COSMIC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	O75030	MITF	P27361	MAPK3	S515	S518I	518	Missense	distal	3	no	10.739	10.688	EPSD	COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	O75030	MITF	P27361	MAPK3	S515	S511I	511	Missense	distal	-4	no	10.739	10.580	EPSD	COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P03372	ESR1	P27361	MAPK3	S104	F97L	97	Missense	distal	-7	no	16.662	16.587	EPSD;PhosphoSitePlus	COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P03372	ESR1	P27361	MAPK3	S104	M109T	109	Missense	distal	5	no	16.662	16.917	EPSD;PhosphoSitePlus	COSMIC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P03372	ESR1	P27361	MAPK3	S106	P113L	113	Missense	distal	7	no	16.212	16.404	EPSD;PhosphoSitePlus	COSMIC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P03372	ESR1	P27361	MAPK3	S106	P113Q	113	Missense	distal	7	no	16.212	16.333	EPSD;PhosphoSitePlus	COSMIC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P03372	ESR1	P27361	MAPK3	S106	H112L	112	Missense	distal	6	no	16.212	16.078	EPSD;PhosphoSitePlus	COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P03372	ESR1	P27361	MAPK3	S106	M109T	109	Missense	distal	3	no	16.212	16.260	EPSD;PhosphoSitePlus	COSMIC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P03372	ESR1	P27361	MAPK3	S118	P113L	113	Missense	distal	-5	no	15.977	15.923	PhosphoSitePlus;EPSD	COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P03372	ESR1	P27361	MAPK3	S118	P113Q	113	Missense	distal	-5	no	15.977	15.929	PhosphoSitePlus;EPSD	COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P03372	ESR1	P27361	MAPK3	S118	L117Q	117	Missense	proximal	-1	no	15.977	15.986	PhosphoSitePlus;EPSD	COSMIC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P03372	ESR1	P27361	MAPK3	S118	H112L	112	Missense	distal	-6	no	15.977	15.810	PhosphoSitePlus;EPSD	COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P03372	ESR1	P27361	MAPK3	S118	S118P	118	Missense	central	0	yes	15.977	0.000	PhosphoSitePlus;EPSD	COSMIC	9.358	Loss
CMGC_MAPK_ERK1_MAPK3_ST	P03372	ESR1	P27361	MAPK3	S294	K299R	299	Missense	distal	5	no	14.592	14.600	EPSD	COSMIC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P03372	ESR1	P27361	MAPK3	S294	P295L	295	Missense	proximal	1	no	14.592	5.554	EPSD	COSMIC	9.358	Loss
CMGC_MAPK_ERK1_MAPK3_ST	P03372	ESR1	P27361	MAPK3	S294	R300C	300	Missense	distal	6	no	14.592	13.966	EPSD	COSMIC;CCLE	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P03372	ESR1	P27361	MAPK3	S294	L296P	296	Missense	proximal	2	no	14.592	14.613	EPSD	COSMIC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P03372	ESR1	P27361	MAPK3	S294	N290K	290	Missense	distal	-4	no	14.592	14.569	EPSD	COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P03372	ESR1	P27361	MAPK3	S294	S294R	294	Missense	central	0	yes	14.592	0.000	EPSD	COSMIC	9.358	Loss
CMGC_MAPK_ERK1_MAPK3_ST	P03372	ESR1	P27361	MAPK3	S294	A288T	288	Missense	distal	-6	no	14.592	14.740	EPSD	COSMIC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P03372	ESR1	P27361	MAPK3	S294	R287H	287	Missense	distal	-7	no	14.592	14.580	EPSD	COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P03372	ESR1	P27361	MAPK3	S294	R287C	287	Missense	distal	-7	no	14.592	14.778	EPSD	COSMIC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P03372	ESR1	P27361	MAPK3	S573	S578Y	578	Missense	distal	5	no	9.490	9.274	EPSD	COSMIC	9.358	Loss
CMGC_MAPK_ERK1_MAPK3_ST	P03372	ESR1	P27361	MAPK3	S575	S578Y	578	Missense	distal	3	no	11.699	11.669	EPSD	COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P03372	ESR1	P27361	MAPK3	S576	S578Y	578	Missense	proximal	2	no	13.096	13.074	EPSD	COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P03372	ESR1	P27361	MAPK3	S578	T585S	585	Missense	distal	7	no	10.031	9.912	EPSD	COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P03372	ESR1	P27361	MAPK3	S578	S578Y	578	Missense	central	0	yes	10.031	0.000	EPSD	COSMIC	9.358	Loss
CMGC_MAPK_ERK1_MAPK3_ST	Q969V6	MRTFA	P27361	MAPK3	S6	L4F	4	Missense	proximal	-2	no	15.035	14.043	EPSD	COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q969V6	MRTFA	P27361	MAPK3	S6	P2S	2	Missense	distal	-4	no	15.035	15.062	EPSD	COSMIC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q969V6	MRTFA	P27361	MAPK3	S6	E12D	12	Missense	distal	6	no	15.035	14.990	EPSD	COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q969V6	MRTFA	P27361	MAPK3	S6	P2L	2	Missense	distal	-4	no	15.035	14.922	EPSD	COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q969V6	MRTFA	P27361	MAPK3	S6	K5E	5	Missense	proximal	-1	no	15.035	15.065	EPSD	COSMIC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q969V6	MRTFA	P27361	MAPK3	S6	P2R	2	Missense	distal	-4	no	15.035	14.985	EPSD	COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q969V6	MRTFA	P27361	MAPK3	S114	S114C	114	Missense	central	0	yes	9.475	0.000	EPSD	COSMIC	9.358	Loss
CMGC_MAPK_ERK1_MAPK3_ST	Q969V6	MRTFA	P27361	MAPK3	S114	D116N	116	Missense	proximal	2	no	9.475	9.469	EPSD	COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q969V6	MRTFA	P27361	MAPK3	S114	P107H	107	Missense	distal	-7	no	9.475	9.509	EPSD	COSMIC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q969V6	MRTFA	P27361	MAPK3	S114	S113C	113	Missense	proximal	-1	no	9.475	9.248	EPSD	COSMIC	9.358	Loss
CMGC_MAPK_ERK1_MAPK3_ST	Q969V6	MRTFA	P27361	MAPK3	S114	D121N	121	Missense	distal	7	no	9.475	9.534	EPSD	COSMIC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q969V6	MRTFA	P27361	MAPK3	S114	K108M	108	Missense	distal	-6	no	9.475	9.212	EPSD	COSMIC	9.358	Loss
CMGC_MAPK_ERK1_MAPK3_ST	Q969V6	MRTFA	P27361	MAPK3	S114	E117K	117	Missense	distal	3	no	9.475	9.464	EPSD	COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q969V6	MRTFA	P27361	MAPK3	S124	E126G	126	Missense	proximal	2	no	14.389	14.381	EPSD	COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q969V6	MRTFA	P27361	MAPK3	S124	E126K	126	Missense	proximal	2	no	14.389	14.381	EPSD	COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q969V6	MRTFA	P27361	MAPK3	S124	P125L	125	Missense	proximal	1	no	14.389	5.351	EPSD	COSMIC	9.358	Loss
CMGC_MAPK_ERK1_MAPK3_ST	Q969V6	MRTFA	P27361	MAPK3	S124	D121N	121	Missense	distal	-3	no	14.389	14.367	EPSD	COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q969V6	MRTFA	P27361	MAPK3	S124	E117K	117	Missense	distal	-7	no	14.389	14.440	EPSD	COSMIC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q969V6	MRTFA	P27361	MAPK3	S130	E126G	126	Missense	distal	-4	no	12.425	12.410	EPSD	COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q969V6	MRTFA	P27361	MAPK3	S130	E126K	126	Missense	distal	-4	no	12.425	12.365	EPSD	COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q969V6	MRTFA	P27361	MAPK3	S130	P125L	125	Missense	distal	-5	no	12.425	12.370	EPSD	COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q969V6	MRTFA	P27361	MAPK3	S133	E126G	126	Missense	distal	-7	no	9.705	9.710	EPSD	COSMIC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q969V6	MRTFA	P27361	MAPK3	S133	E126K	126	Missense	distal	-7	no	9.705	9.756	EPSD	COSMIC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q969V6	MRTFA	P27361	MAPK3	S133	P138L	138	Missense	distal	5	no	9.705	9.477	EPSD	COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q969V6	MRTFA	P27361	MAPK3	S139	P138L	138	Missense	proximal	-1	no	16.084	15.989	EPSD	COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q969V6	MRTFA	P27361	MAPK3	S139	R144G	144	Missense	distal	5	no	16.084	16.163	EPSD	COSMIC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q969V6	MRTFA	P27361	MAPK3	S156	P157H	157	Missense	proximal	1	no	17.380	9.624	EPSD	COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q969V6	MRTFA	P27361	MAPK3	S156	S154C	154	Missense	proximal	-2	no	17.380	14.940	EPSD	COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q969V6	MRTFA	P27361	MAPK3	S156	P157S	157	Missense	proximal	1	no	17.380	8.327	EPSD	COSMIC	9.358	Loss
CMGC_MAPK_ERK1_MAPK3_ST	Q969V6	MRTFA	P27361	MAPK3	S156	Q163P	163	Missense	distal	7	no	17.380	17.258	EPSD	COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q969V6	MRTFA	P27361	MAPK3	S162	Q163P	163	Missense	proximal	1	no	7.734	15.678	EPSD	COSMIC	9.358	Gain
CMGC_MAPK_ERK1_MAPK3_ST	Q969V6	MRTFA	P27361	MAPK3	T204	P205S	205	Missense	proximal	1	no	14.685	5.632	EPSD	COSMIC	9.358	Loss
CMGC_MAPK_ERK1_MAPK3_ST	Q969V6	MRTFA	P27361	MAPK3	T204	P205H	205	Missense	proximal	1	no	14.685	6.929	EPSD	COSMIC	9.358	Loss
CMGC_MAPK_ERK1_MAPK3_ST	Q969V6	MRTFA	P27361	MAPK3	T204	K202T	202	Missense	proximal	-2	no	14.685	16.040	EPSD	COSMIC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q969V6	MRTFA	P27361	MAPK3	T204	K202E	202	Missense	proximal	-2	no	14.685	15.379	EPSD	COSMIC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q969V6	MRTFA	P27361	MAPK3	T204	P205L	205	Missense	proximal	1	no	14.685	5.647	EPSD	COSMIC	9.358	Loss
CMGC_MAPK_ERK1_MAPK3_ST	Q969V6	MRTFA	P27361	MAPK3	T305	P307S	307	Missense	proximal	2	no	14.807	14.809	EPSD	COSMIC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q969V6	MRTFA	P27361	MAPK3	T305	R309C	309	Missense	distal	4	no	14.807	14.450	EPSD	COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q969V6	MRTFA	P27361	MAPK3	T305	E298K	298	Missense	distal	-7	no	14.807	14.858	EPSD	COSMIC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q969V6	MRTFA	P27361	MAPK3	T305	S312P	312	Missense	distal	7	no	14.807	14.884	EPSD	COSMIC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q969V6	MRTFA	P27361	MAPK3	T305	S302R	302	Missense	distal	-3	no	14.807	14.769	EPSD	COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q969V6	MRTFA	P27361	MAPK3	T305	S303R	303	Missense	proximal	-2	no	14.807	14.483	EPSD	COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q969V6	MRTFA	P27361	MAPK3	S316	S319G	319	Missense	distal	3	no	10.121	10.106	EPSD	COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q969V6	MRTFA	P27361	MAPK3	S316	R309C	309	Missense	distal	-7	no	10.121	10.308	EPSD	COSMIC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q969V6	MRTFA	P27361	MAPK3	S316	S320L	320	Missense	distal	4	no	10.121	9.918	EPSD	COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q969V6	MRTFA	P27361	MAPK3	S316	S312P	312	Missense	distal	-4	no	10.121	10.094	EPSD	COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q969V6	MRTFA	P27361	MAPK3	S316	S320G	320	Missense	distal	4	no	10.121	9.960	EPSD	COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q969V6	MRTFA	P27361	MAPK3	S385	P391L	391	Missense	distal	6	no	16.483	16.256	EPSD	COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q969V6	MRTFA	P27361	MAPK3	T450	P457S	457	Missense	distal	7	no	14.442	14.365	EPSD	COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q969V6	MRTFA	P27361	MAPK3	T450	G448S	448	Missense	proximal	-2	no	14.442	15.482	EPSD	COSMIC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q969V6	MRTFA	P27361	MAPK3	T450	P451S	451	Missense	proximal	1	no	14.442	5.389	EPSD	COSMIC	9.358	Loss
CMGC_MAPK_ERK1_MAPK3_ST	Q969V6	MRTFA	P27361	MAPK3	T450	T447M	447	Missense	distal	-3	no	14.442	14.345	EPSD	COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q969V6	MRTFA	P27361	MAPK3	T450	P452S	452	Missense	proximal	2	no	14.442	14.444	EPSD	COSMIC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q969V6	MRTFA	P27361	MAPK3	S454	P457S	457	Missense	distal	3	no	18.254	18.250	PhosphoSitePlus	COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q969V6	MRTFA	P27361	MAPK3	S454	R460H	460	Missense	distal	6	no	18.254	18.273	PhosphoSitePlus	COSMIC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q969V6	MRTFA	P27361	MAPK3	S454	G448S	448	Missense	distal	-6	no	18.254	18.317	PhosphoSitePlus	COSMIC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q969V6	MRTFA	P27361	MAPK3	S454	P451S	451	Missense	distal	-3	no	18.254	18.246	PhosphoSitePlus	COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q969V6	MRTFA	P27361	MAPK3	S454	R460L	460	Missense	distal	6	no	18.254	18.140	PhosphoSitePlus	COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q969V6	MRTFA	P27361	MAPK3	S454	T447M	447	Missense	distal	-7	no	18.254	18.383	PhosphoSitePlus	COSMIC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q969V6	MRTFA	P27361	MAPK3	S454	P452S	452	Missense	proximal	-2	no	18.254	17.178	PhosphoSitePlus	COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q969V6	MRTFA	P27361	MAPK3	T456	P457S	457	Missense	proximal	1	no	15.933	6.879	EPSD	COSMIC	9.358	Loss
CMGC_MAPK_ERK1_MAPK3_ST	Q969V6	MRTFA	P27361	MAPK3	T456	R460H	460	Missense	distal	4	no	15.933	15.939	EPSD	COSMIC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q969V6	MRTFA	P27361	MAPK3	T456	P451S	451	Missense	distal	-5	no	15.933	15.938	EPSD	COSMIC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q969V6	MRTFA	P27361	MAPK3	T456	R460L	460	Missense	distal	4	no	15.933	15.876	EPSD	COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q969V6	MRTFA	P27361	MAPK3	T456	P452S	452	Missense	distal	-4	no	15.933	15.960	EPSD	COSMIC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q969V6	MRTFA	P27361	MAPK3	T471	G477C	477	Missense	distal	6	no	15.026	14.392	EPSD	COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q969V6	MRTFA	P27361	MAPK3	T471	G473V	473	Missense	proximal	2	no	15.026	15.018	EPSD	COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q969V6	MRTFA	P27361	MAPK3	T471	P472H	472	Missense	proximal	1	no	15.026	7.271	EPSD	COSMIC	9.358	Loss
CMGC_MAPK_ERK1_MAPK3_ST	Q969V6	MRTFA	P27361	MAPK3	T471	G473R	473	Missense	proximal	2	no	15.026	15.031	EPSD	COSMIC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q969V6	MRTFA	P27361	MAPK3	T471	E468D	468	Missense	distal	-3	no	15.026	15.023	EPSD	COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q969V6	MRTFA	P27361	MAPK3	T471	D474G	474	Missense	distal	3	no	15.026	15.022	EPSD	COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q969V6	MRTFA	P27361	MAPK3	T471	E468K	468	Missense	distal	-3	no	15.026	14.995	EPSD	COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q969V6	MRTFA	P27361	MAPK3	T471	D474Y	474	Missense	distal	3	no	15.026	15.007	EPSD	COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q969V6	MRTFA	P27361	MAPK3	T471	P472T	472	Missense	proximal	1	no	15.026	6.149	EPSD	COSMIC	9.358	Loss
CMGC_MAPK_ERK1_MAPK3_ST	Q969V6	MRTFA	P27361	MAPK3	S482	G477C	477	Missense	distal	-5	no	15.230	15.111	EPSD	COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q969V6	MRTFA	P27361	MAPK3	S482	M479T	479	Missense	distal	-3	no	15.230	15.327	EPSD	COSMIC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q969V6	MRTFA	P27361	MAPK3	S482	T485M	485	Missense	distal	3	no	15.230	15.181	EPSD	COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q969V6	MRTFA	P27361	MAPK3	S482	L489P	489	Missense	distal	7	no	15.230	15.037	EPSD	COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q969V6	MRTFA	P27361	MAPK3	S482	T488A	488	Missense	distal	6	no	15.230	14.859	EPSD	COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q969V6	MRTFA	P27361	MAPK3	S482	T485A	485	Missense	distal	3	no	15.230	15.199	EPSD	COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q969V6	MRTFA	P27361	MAPK3	S482	P483H	483	Missense	proximal	1	no	15.230	7.474	EPSD	COSMIC	9.358	Loss
CMGC_MAPK_ERK1_MAPK3_ST	Q969V6	MRTFA	P27361	MAPK3	S482	T488M	488	Missense	distal	6	no	15.230	14.735	EPSD	COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q969V6	MRTFA	P27361	MAPK3	S511	A516G	516	Missense	distal	5	no	13.970	14.160	EPSD	COSMIC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q969V6	MRTFA	P27361	MAPK3	S511	A516T	516	Missense	distal	5	no	13.970	14.089	EPSD	COSMIC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q969V6	MRTFA	P27361	MAPK3	S511	P512H	512	Missense	proximal	1	no	13.970	6.214	EPSD	COSMIC	9.358	Loss
CMGC_MAPK_ERK1_MAPK3_ST	Q969V6	MRTFA	P27361	MAPK3	S511	G513E	513	Missense	proximal	2	no	13.970	13.978	EPSD	COSMIC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q969V6	MRTFA	P27361	MAPK3	S511	P512S	512	Missense	proximal	1	no	13.970	4.916	EPSD	COSMIC	9.358	Loss
CMGC_MAPK_ERK1_MAPK3_ST	Q969V6	MRTFA	P27361	MAPK3	S511	L518V	518	Missense	distal	7	no	13.970	14.018	EPSD	COSMIC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q969V6	MRTFA	P27361	MAPK3	S511	C509Y	509	Missense	proximal	-2	no	13.970	16.177	EPSD	COSMIC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q969V6	MRTFA	P27361	MAPK3	S511	R515L	515	Missense	distal	4	no	13.970	13.913	EPSD	COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q969V6	MRTFA	P27361	MAPK3	S511	R504L	504	Missense	distal	-7	no	13.970	14.032	EPSD	COSMIC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q969V6	MRTFA	P27361	MAPK3	S511	A516V	516	Missense	distal	5	no	13.970	13.958	EPSD	COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q969V6	MRTFA	P27361	MAPK3	S511	R515Q	515	Missense	distal	4	no	13.970	13.925	EPSD	COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q969V6	MRTFA	P27361	MAPK3	S511	R515W	515	Missense	distal	4	no	13.970	13.502	EPSD	COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q969V6	MRTFA	P27361	MAPK3	S511	G514E	514	Missense	distal	3	no	13.970	13.972	EPSD	COSMIC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q969V6	MRTFA	P27361	MAPK3	T573	L571P	571	Missense	proximal	-2	no	15.710	17.094	EPSD	COSMIC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q969V6	MRTFA	P27361	MAPK3	T573	A569P	569	Missense	distal	-4	no	15.710	15.815	EPSD	COSMIC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q969V6	MRTFA	P27361	MAPK3	T573	K576R	576	Missense	distal	3	no	15.710	15.712	EPSD	COSMIC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q969V6	MRTFA	P27361	MAPK3	T573	A567P	567	Missense	distal	-6	no	15.710	15.942	EPSD	COSMIC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q969V6	MRTFA	P27361	MAPK3	T573	P566L	566	Missense	distal	-7	no	15.710	15.817	EPSD	COSMIC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q969V6	MRTFA	P27361	MAPK3	T573	T573M	573	Missense	central	0	yes	15.710	0.000	EPSD	COSMIC	9.358	Loss
CMGC_MAPK_ERK1_MAPK3_ST	Q969V6	MRTFA	P27361	MAPK3	S691	S695L	695	Missense	distal	4	no	9.810	9.607	EPSD	COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q969V6	MRTFA	P27361	MAPK3	S691	P698R	698	Missense	distal	7	no	9.810	9.902	EPSD	COSMIC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q969V6	MRTFA	P27361	MAPK3	S691	S695I	695	Missense	distal	4	no	9.810	9.469	EPSD	COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q969V6	MRTFA	P27361	MAPK3	S695	S695L	695	Missense	central	0	yes	19.377	0.000	EPSD	COSMIC	9.358	Loss
CMGC_MAPK_ERK1_MAPK3_ST	Q969V6	MRTFA	P27361	MAPK3	S695	A699V	699	Missense	distal	4	no	19.377	19.485	EPSD	COSMIC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q969V6	MRTFA	P27361	MAPK3	S695	P698R	698	Missense	distal	3	no	19.377	19.350	EPSD	COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q969V6	MRTFA	P27361	MAPK3	S695	S701F	701	Missense	distal	6	no	19.377	18.663	EPSD	COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q969V6	MRTFA	P27361	MAPK3	S695	A702G	702	Missense	distal	7	no	19.377	19.170	EPSD	COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q969V6	MRTFA	P27361	MAPK3	S695	S695I	695	Missense	central	0	yes	19.377	0.000	EPSD	COSMIC	9.358	Loss
CMGC_MAPK_ERK1_MAPK3_ST	Q969V6	MRTFA	P27361	MAPK3	S785	P779L	779	Missense	distal	-6	no	15.049	14.802	EPSD	COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q969V6	MRTFA	P27361	MAPK3	S785	S785P	785	Missense	central	0	yes	15.049	0.000	EPSD	COSMIC	9.358	Loss
CMGC_MAPK_ERK1_MAPK3_ST	Q969V6	MRTFA	P27361	MAPK3	S785	P779S	779	Missense	distal	-6	no	15.049	15.134	EPSD	COSMIC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q969V6	MRTFA	P27361	MAPK3	S792	S785P	785	Missense	distal	-7	no	14.836	14.874	EPSD	COSMIC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q969V6	MRTFA	P27361	MAPK3	S807	R813C	813	Missense	distal	6	no	18.667	18.042	EPSD	COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q969V6	MRTFA	P27361	MAPK3	S807	P808T	808	Missense	proximal	1	no	18.667	9.790	EPSD	COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q969V6	MRTFA	P27361	MAPK3	S807	P805A	805	Missense	proximal	-2	no	18.667	16.317	EPSD	COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q969V6	MRTFA	P27361	MAPK3	S807	S809P	809	Missense	proximal	2	no	18.667	18.665	EPSD	COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q969V6	MRTFA	P27361	MAPK3	S807	P803L	803	Missense	distal	-4	no	18.667	18.555	EPSD	COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q969V6	MRTFA	P27361	MAPK3	S859	S859P	859	Missense	central	0	yes	17.202	0.000	EPSD	COSMIC	9.358	Loss
CMGC_MAPK_ERK1_MAPK3_ST	Q969V6	MRTFA	P27361	MAPK3	S859	H856R	856	Missense	distal	-3	no	17.202	17.196	EPSD	COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q969V6	MRTFA	P27361	MAPK3	S859	I853V	853	Missense	distal	-6	no	17.202	17.271	EPSD	COSMIC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q13614	MTMR2	P27361	MAPK3	S21	A28V	28	Missense	distal	7	no	10.732	10.704	EPSD	COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q13614	MTMR2	P27361	MAPK3	S21	A28T	28	Missense	distal	7	no	10.732	10.505	EPSD	COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q13614	MTMR2	P27361	MAPK3	S26	A28V	28	Missense	proximal	2	no	10.236	10.249	EPSD	COSMIC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q13614	MTMR2	P27361	MAPK3	S26	A28T	28	Missense	proximal	2	no	10.236	10.263	EPSD	COSMIC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q13614	MTMR2	P27361	MAPK3	S27	A28V	28	Missense	proximal	1	no	10.494	10.311	EPSD	COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q13614	MTMR2	P27361	MAPK3	S27	A28T	28	Missense	proximal	1	no	10.494	10.856	EPSD	COSMIC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q13614	MTMR2	P27361	MAPK3	S29	A28V	28	Missense	proximal	-1	no	10.079	10.129	EPSD	COSMIC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q13614	MTMR2	P27361	MAPK3	S29	A28T	28	Missense	proximal	-1	no	10.079	10.183	EPSD	COSMIC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q13614	MTMR2	P27361	MAPK3	S58	R62M	62	Missense	distal	4	no	14.679	14.447	PhosphoSitePlus	COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q13614	MTMR2	P27361	MAPK3	S58	D55N	55	Missense	distal	-3	no	14.679	14.657	PhosphoSitePlus	COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q13614	MTMR2	P27361	MAPK3	S58	V63I	63	Missense	distal	5	no	14.679	14.552	PhosphoSitePlus	COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q13614	MTMR2	P27361	MAPK3	S622	R621Q	621	Missense	proximal	-1	no	10.697	10.658	EPSD	COSMIC;GDSC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q13614	MTMR2	P27361	MAPK3	S622	A629T	629	Missense	distal	7	no	10.697	10.469	EPSD	COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q13614	MTMR2	P27361	MAPK3	S622	A629S	629	Missense	distal	7	no	10.697	10.351	EPSD	COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q13614	MTMR2	P27361	MAPK3	S624	R621Q	621	Missense	distal	-3	no	10.491	10.484	EPSD	COSMIC;GDSC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q13614	MTMR2	P27361	MAPK3	S624	A629T	629	Missense	distal	5	no	10.491	10.611	EPSD	COSMIC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q13614	MTMR2	P27361	MAPK3	S624	A629S	629	Missense	distal	5	no	10.491	10.747	EPSD	COSMIC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q13614	MTMR2	P27361	MAPK3	S625	R621Q	621	Missense	distal	-4	no	11.539	11.549	EPSD	COSMIC;GDSC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q13614	MTMR2	P27361	MAPK3	S625	A629T	629	Missense	distal	4	no	11.539	11.757	EPSD	COSMIC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q13614	MTMR2	P27361	MAPK3	S625	A629S	629	Missense	distal	4	no	11.539	11.870	EPSD	COSMIC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q13614	MTMR2	P27361	MAPK3	S626	R621Q	621	Missense	distal	-5	no	11.190	11.183	EPSD	COSMIC;GDSC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q13614	MTMR2	P27361	MAPK3	S626	A629T	629	Missense	distal	3	no	11.190	11.220	EPSD	COSMIC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q13614	MTMR2	P27361	MAPK3	S626	A629S	629	Missense	distal	3	no	11.190	11.234	EPSD	COSMIC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q13614	MTMR2	P27361	MAPK3	S630	A629T	629	Missense	proximal	-1	no	9.300	9.403	EPSD	COSMIC	9.358	Gain
CMGC_MAPK_ERK1_MAPK3_ST	Q13614	MTMR2	P27361	MAPK3	S630	A629S	629	Missense	proximal	-1	no	9.300	9.433	EPSD	COSMIC	9.358	Gain
CMGC_MAPK_ERK1_MAPK3_ST	Q13614	MTMR2	P27361	MAPK3	S631	A629T	629	Missense	proximal	-2	no	17.752	19.117	EPSD	COSMIC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q13614	MTMR2	P27361	MAPK3	S631	P638S	638	Missense	distal	7	no	17.752	17.674	EPSD	COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q13614	MTMR2	P27361	MAPK3	S631	A629S	629	Missense	proximal	-2	no	17.752	19.026	EPSD	COSMIC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q13614	MTMR2	P27361	MAPK3	T637	P638S	638	Missense	proximal	1	no	16.641	7.587	EPSD	COSMIC	9.358	Loss
CMGC_MAPK_ERK1_MAPK3_ST	Q13614	MTMR2	P27361	MAPK3	T637	Q640K	640	Missense	distal	3	no	16.641	16.639	EPSD	COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P41212	ETV6	P27361	MAPK3	T4	C8Y	8	Missense	distal	4	no	13.152	13.439	EPSD	COSMIC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P41212	ETV6	P27361	MAPK3	T4	S2C	2	Missense	proximal	-2	no	13.152	10.712	EPSD	COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P41212	ETV6	P27361	MAPK3	T4	T4I	4	Missense	central	0	yes	13.152	0.000	EPSD	COSMIC	9.358	Loss
CMGC_MAPK_ERK1_MAPK3_ST	P41212	ETV6	P27361	MAPK3	S16	P23Q	23	Missense	distal	7	no	10.814	10.936	EPSD	COSMIC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P41212	ETV6	P27361	MAPK3	S16	S22R	22	Missense	distal	6	no	10.814	10.572	EPSD	COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P41212	ETV6	P27361	MAPK3	T18	P25R	25	Missense	distal	7	no	18.242	18.334	EPSD	COSMIC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P41212	ETV6	P27361	MAPK3	T18	P23Q	23	Missense	distal	5	no	18.242	18.139	EPSD	COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P41212	ETV6	P27361	MAPK3	T18	S22R	22	Missense	distal	4	no	18.242	18.095	EPSD	COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P41212	ETV6	P27361	MAPK3	S22	A28P	28	Missense	distal	6	no	18.707	19.103	EPSD	COSMIC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P41212	ETV6	P27361	MAPK3	S22	P25R	25	Missense	distal	3	no	18.707	18.681	EPSD	COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P41212	ETV6	P27361	MAPK3	S22	P23Q	23	Missense	proximal	1	no	18.707	10.763	EPSD	COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P41212	ETV6	P27361	MAPK3	S22	A28V	28	Missense	distal	6	no	18.707	18.794	EPSD	COSMIC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P41212	ETV6	P27361	MAPK3	S22	S22R	22	Missense	central	0	yes	18.707	0.000	EPSD	COSMIC	9.358	Loss
CMGC_MAPK_ERK1_MAPK3_ST	P41212	ETV6	P27361	MAPK3	S22	S29F	29	Missense	distal	7	no	18.707	19.198	EPSD	COSMIC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P41212	ETV6	P27361	MAPK3	S26	A28P	28	Missense	proximal	2	no	12.337	12.374	EPSD	COSMIC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P41212	ETV6	P27361	MAPK3	S26	P25R	25	Missense	proximal	-1	no	12.337	12.289	EPSD	COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P41212	ETV6	P27361	MAPK3	S26	P23Q	23	Missense	distal	-3	no	12.337	12.283	EPSD	COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P41212	ETV6	P27361	MAPK3	S26	A28V	28	Missense	proximal	2	no	12.337	12.350	EPSD	COSMIC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P41212	ETV6	P27361	MAPK3	S26	S22R	22	Missense	distal	-4	no	12.337	12.260	EPSD	COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P41212	ETV6	P27361	MAPK3	S26	S29F	29	Missense	distal	3	no	12.337	12.272	EPSD	COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P41212	ETV6	P27361	MAPK3	S29	A28P	28	Missense	proximal	-1	no	9.503	9.642	EPSD	COSMIC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P41212	ETV6	P27361	MAPK3	S29	P25R	25	Missense	distal	-4	no	9.503	9.453	EPSD	COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P41212	ETV6	P27361	MAPK3	S29	P23Q	23	Missense	distal	-6	no	9.503	9.437	EPSD	COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P41212	ETV6	P27361	MAPK3	S29	A28V	28	Missense	proximal	-1	no	9.503	9.552	EPSD	COSMIC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P41212	ETV6	P27361	MAPK3	S29	P36L	36	Missense	distal	7	no	9.503	9.695	EPSD	COSMIC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P41212	ETV6	P27361	MAPK3	S29	S22R	22	Missense	distal	-7	no	9.503	9.586	EPSD	COSMIC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P41212	ETV6	P27361	MAPK3	S29	S29F	29	Missense	central	0	yes	9.503	0.000	EPSD	COSMIC	9.358	Loss
CMGC_MAPK_ERK1_MAPK3_ST	P41212	ETV6	P27361	MAPK3	S30	A28P	28	Missense	proximal	-2	no	7.612	9.963	EPSD	COSMIC	9.358	Gain
CMGC_MAPK_ERK1_MAPK3_ST	P41212	ETV6	P27361	MAPK3	T31	A28P	28	Missense	distal	-3	no	15.403	15.503	EPSD	COSMIC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P41212	ETV6	P27361	MAPK3	T31	P25R	25	Missense	distal	-6	no	15.403	15.327	EPSD	COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P41212	ETV6	P27361	MAPK3	T31	A28V	28	Missense	distal	-3	no	15.403	15.422	EPSD	COSMIC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P41212	ETV6	P27361	MAPK3	T31	P36L	36	Missense	distal	5	no	15.403	15.175	EPSD	COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P41212	ETV6	P27361	MAPK3	T31	P38L	38	Missense	distal	7	no	15.403	15.596	EPSD	COSMIC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P41212	ETV6	P27361	MAPK3	T31	S29F	29	Missense	proximal	-2	no	15.403	14.103	EPSD	COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P41212	ETV6	P27361	MAPK3	S47	I48F	48	Missense	proximal	1	no	7.604	10.898	EPSD	COSMIC	9.358	Gain
CMGC_MAPK_ERK1_MAPK3_ST	P41212	ETV6	P27361	MAPK3	T86	D83E	83	Missense	distal	-3	no	10.112	10.115	EPSD	COSMIC;GDSC;CCLE	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P41212	ETV6	P27361	MAPK3	S131	G137V	137	Missense	distal	6	no	15.976	15.770	EPSD	COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P41212	ETV6	P27361	MAPK3	S131	P132S	132	Missense	proximal	1	no	15.976	6.923	EPSD	COSMIC	9.358	Loss
CMGC_MAPK_ERK1_MAPK3_ST	P41212	ETV6	P27361	MAPK3	S131	P136S	136	Missense	distal	5	no	15.976	16.019	EPSD	COSMIC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P41212	ETV6	P27361	MAPK3	T161	N156S	156	Missense	distal	-5	no	13.998	14.039	EPSD	COSMIC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P41212	ETV6	P27361	MAPK3	T161	D155Y	155	Missense	distal	-6	no	13.998	13.806	EPSD	COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P41212	ETV6	P27361	MAPK3	T161	Q159R	159	Missense	proximal	-2	no	13.998	14.362	EPSD	COSMIC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P41212	ETV6	P27361	MAPK3	T161	P162S	162	Missense	proximal	1	no	13.998	4.945	EPSD	COSMIC	9.358	Loss
CMGC_MAPK_ERK1_MAPK3_ST	P41212	ETV6	P27361	MAPK3	T161	S165C	165	Missense	distal	4	no	13.998	13.495	EPSD	COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P41212	ETV6	P27361	MAPK3	T161	V166M	166	Missense	distal	5	no	13.998	13.874	EPSD	COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P41212	ETV6	P27361	MAPK3	T161	D167H	167	Missense	distal	6	no	13.998	13.952	EPSD	COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P41212	ETV6	P27361	MAPK3	S184	E177Q	177	Missense	distal	-7	no	16.650	16.700	EPSD	COSMIC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P41212	ETV6	P27361	MAPK3	S184	I186V	186	Missense	proximal	2	no	16.650	16.660	EPSD	COSMIC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P41212	ETV6	P27361	MAPK3	S184	R191W	191	Missense	distal	7	no	16.650	17.226	EPSD	COSMIC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P41212	ETV6	P27361	MAPK3	S193	P194A	194	Missense	proximal	1	no	16.703	7.463	EPSD	COSMIC;GDSC;CCLE	9.358	Loss
CMGC_MAPK_ERK1_MAPK3_ST	P41212	ETV6	P27361	MAPK3	S193	P194L	194	Missense	proximal	1	no	16.703	7.665	EPSD	COSMIC	9.358	Loss
CMGC_MAPK_ERK1_MAPK3_ST	P41212	ETV6	P27361	MAPK3	S193	P200L	200	Missense	distal	7	no	16.703	16.895	EPSD	COSMIC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P41212	ETV6	P27361	MAPK3	S193	I186V	186	Missense	distal	-7	no	16.703	16.661	EPSD	COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P41212	ETV6	P27361	MAPK3	S193	R191W	191	Missense	proximal	-2	no	16.703	14.806	EPSD	COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P41212	ETV6	P27361	MAPK3	S203	L201P	201	Missense	proximal	-2	no	17.076	18.460	EPSD	COSMIC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P41212	ETV6	P27361	MAPK3	S203	P204S	204	Missense	proximal	1	no	17.076	8.023	EPSD	COSMIC	9.358	Loss
CMGC_MAPK_ERK1_MAPK3_ST	P41212	ETV6	P27361	MAPK3	S203	P200L	200	Missense	distal	-3	no	17.076	16.992	EPSD	COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P41212	ETV6	P27361	MAPK3	S213	R211C	211	Missense	proximal	-2	no	15.938	13.822	EPSD;PhosphoSitePlus	COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P41212	ETV6	P27361	MAPK3	S213	S213F	213	Missense	central	0	yes	15.938	0.000	EPSD;PhosphoSitePlus	COSMIC	9.358	Loss
CMGC_MAPK_ERK1_MAPK3_ST	P41212	ETV6	P27361	MAPK3	S213	A218T	218	Missense	distal	5	no	15.938	16.058	EPSD;PhosphoSitePlus	COSMIC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P41212	ETV6	P27361	MAPK3	S236	S236L	236	Missense	central	0	yes	10.493	0.000	EPSD	COSMIC	9.358	Loss
CMGC_MAPK_ERK1_MAPK3_ST	P41212	ETV6	P27361	MAPK3	S236	P239S	239	Missense	distal	3	no	10.493	10.489	EPSD	COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P41212	ETV6	P27361	MAPK3	S236	E231Q	231	Missense	distal	-5	no	10.493	10.475	EPSD	COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P41212	ETV6	P27361	MAPK3	S238	C245Y	245	Missense	distal	7	no	17.742	17.385	EPSD	COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P41212	ETV6	P27361	MAPK3	S238	H244Y	244	Missense	distal	6	no	17.742	17.582	EPSD	COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P41212	ETV6	P27361	MAPK3	S238	S236L	236	Missense	proximal	-2	no	17.742	17.433	EPSD	COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P41212	ETV6	P27361	MAPK3	S238	P239S	239	Missense	proximal	1	no	17.742	8.688	EPSD	COSMIC	9.358	Loss
CMGC_MAPK_ERK1_MAPK3_ST	P41212	ETV6	P27361	MAPK3	S238	E231Q	231	Missense	distal	-7	no	17.742	17.791	EPSD	COSMIC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P41212	ETV6	P27361	MAPK3	S248	C245Y	245	Missense	distal	-3	no	9.596	9.711	EPSD	COSMIC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P41212	ETV6	P27361	MAPK3	S248	H244Y	244	Missense	distal	-4	no	9.596	9.556	EPSD	COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P41212	ETV6	P27361	MAPK3	S248	P253S	253	Missense	distal	5	no	9.596	9.639	EPSD	COSMIC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P41212	ETV6	P27361	MAPK3	S257	R259W	259	Missense	proximal	2	no	18.675	18.615	PhosphoSitePlus;EPSD	COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P41212	ETV6	P27361	MAPK3	S257	R259Q	259	Missense	proximal	2	no	18.675	18.666	PhosphoSitePlus;EPSD	COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P41212	ETV6	P27361	MAPK3	S257	E261K	261	Missense	distal	4	no	18.675	18.637	PhosphoSitePlus;EPSD	COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P41212	ETV6	P27361	MAPK3	S257	R259G	259	Missense	proximal	2	no	18.675	18.671	PhosphoSitePlus;EPSD	COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P41212	ETV6	P27361	MAPK3	S257	P253S	253	Missense	distal	-4	no	18.675	18.703	PhosphoSitePlus;EPSD	COSMIC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P41212	ETV6	P27361	MAPK3	S271	P270S	270	Missense	proximal	-1	no	15.378	15.372	EPSD	COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P41212	ETV6	P27361	MAPK3	S271	P272R	272	Missense	proximal	1	no	15.378	5.877	EPSD	COSMIC	9.358	Loss
CMGC_MAPK_ERK1_MAPK3_ST	P41212	ETV6	P27361	MAPK3	S271	L277P	277	Missense	distal	6	no	15.378	15.605	EPSD	COSMIC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P41212	ETV6	P27361	MAPK3	S307	L306F	306	Missense	proximal	-1	no	9.603	9.488	EPSD	COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P41212	ETV6	P27361	MAPK3	S307	I304M	304	Missense	distal	-3	no	9.603	9.587	EPSD	COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P41212	ETV6	P27361	MAPK3	S323	P324Q	324	Missense	proximal	1	no	16.845	8.901	EPSD	COSMIC	9.358	Loss
CMGC_MAPK_ERK1_MAPK3_ST	P41212	ETV6	P27361	MAPK3	S323	A329T	329	Missense	distal	6	no	16.845	17.216	EPSD	COSMIC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P41212	ETV6	P27361	MAPK3	S323	H328Y	328	Missense	distal	5	no	16.845	16.737	EPSD	COSMIC;GDSC;CCLE	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P41212	ETV6	P27361	MAPK3	T422	S428G	428	Missense	distal	6	no	14.210	13.978	EPSD	COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P41212	ETV6	P27361	MAPK3	T422	E425G	425	Missense	distal	3	no	14.210	14.208	EPSD	COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P41212	ETV6	P27361	MAPK3	T422	S428N	428	Missense	distal	6	no	14.210	13.981	EPSD	COSMIC;GDSC;CCLE	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P41212	ETV6	P27361	MAPK3	T422	R418G	418	Missense	distal	-4	no	14.210	14.249	EPSD	COSMIC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P41212	ETV6	P27361	MAPK3	T422	F417L	417	Missense	distal	-5	no	14.210	14.285	EPSD	COSMIC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P41212	ETV6	P27361	MAPK3	T422	L415V	415	Missense	distal	-7	no	14.210	14.215	EPSD	COSMIC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P41212	ETV6	P27361	MAPK3	T422	F417C	417	Missense	distal	-5	no	14.210	14.183	EPSD	COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P41212	ETV6	P27361	MAPK3	T422	M427I	427	Missense	distal	5	no	14.210	14.208	EPSD	COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P41212	ETV6	P27361	MAPK3	T422	R418M	418	Missense	distal	-4	no	14.210	14.107	EPSD	COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P41212	ETV6	P27361	MAPK3	T422	M420I	420	Missense	proximal	-2	no	14.210	15.126	EPSD	COSMIC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P41212	ETV6	P27361	MAPK3	S439	S439F	439	Missense	central	0	yes	9.952	0.000	EPSD	COSMIC	9.358	Loss
CMGC_MAPK_ERK1_MAPK3_ST	P41212	ETV6	P27361	MAPK3	S439	Q440L	440	Missense	proximal	1	no	9.952	8.858	EPSD	COSMIC	9.358	Loss
CMGC_MAPK_ERK1_MAPK3_ST	P41212	ETV6	P27361	MAPK3	S439	E441K	441	Missense	proximal	2	no	9.952	9.945	EPSD	COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P41212	ETV6	P27361	MAPK3	S439	L434V	434	Missense	distal	-5	no	9.952	9.936	EPSD	COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P19419	ELK1	P27361	MAPK3	T133	P131Q	131	Missense	proximal	-2	no	15.764	14.000	EPSD	COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P19419	ELK1	P27361	MAPK3	T133	K130N	130	Missense	distal	-3	no	15.764	15.770	EPSD	COSMIC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P19419	ELK1	P27361	MAPK3	T133	P134S	134	Missense	proximal	1	no	15.764	6.710	EPSD	COSMIC	9.358	Loss
CMGC_MAPK_ERK1_MAPK3_ST	P19419	ELK1	P27361	MAPK3	S304	P305S	305	Missense	proximal	1	no	14.893	5.840	EPSD	COSMIC	9.358	Loss
CMGC_MAPK_ERK1_MAPK3_ST	P19419	ELK1	P27361	MAPK3	S304	Q309R	309	Missense	distal	5	no	14.893	14.895	EPSD	COSMIC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P19419	ELK1	P27361	MAPK3	T336	R335W	335	Missense	proximal	-1	no	15.581	15.343	EPSD	COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P19419	ELK1	P27361	MAPK3	T353	Q346H	346	Missense	distal	-7	no	14.553	14.543	EPSD	COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P19419	ELK1	P27361	MAPK3	T353	A351G	351	Missense	proximal	-2	no	14.553	14.788	EPSD	COSMIC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P19419	ELK1	P27361	MAPK3	S383	R388C	388	Missense	distal	5	no	16.736	16.357	EPSD;PhosphoSitePlus	COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P19419	ELK1	P27361	MAPK3	S383	S380I	380	Missense	distal	-3	no	16.736	16.625	EPSD;PhosphoSitePlus	COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P19419	ELK1	P27361	MAPK3	S389	S394P	394	Missense	distal	5	no	16.106	16.063	PhosphoSitePlus;EPSD	COSMIC;GDSC;CCLE	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P19419	ELK1	P27361	MAPK3	S389	R388C	388	Missense	proximal	-1	no	16.106	15.921	PhosphoSitePlus;EPSD	COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P19419	ELK1	P27361	MAPK3	S389	S394F	394	Missense	distal	5	no	16.106	15.681	PhosphoSitePlus;EPSD	COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P19419	ELK1	P27361	MAPK3	S411	S409F	409	Missense	proximal	-2	no	10.146	8.846	EPSD	COSMIC	9.358	Loss
CMGC_MAPK_ERK1_MAPK3_ST	P19419	ELK1	P27361	MAPK3	S422	P425S	425	Missense	distal	3	no	21.537	21.532	EPSD	COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P12980	LYL1	P27361	MAPK3	S25	P32A	32	Missense	distal	7	no	18.155	18.424	EPSD	COSMIC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P12980	LYL1	P27361	MAPK3	S25	S25N	25	Missense	central	0	yes	18.155	0.000	EPSD	COSMIC	9.358	Loss
CMGC_MAPK_ERK1_MAPK3_ST	P12980	LYL1	P27361	MAPK3	S36	E43K	43	Missense	distal	7	no	17.023	17.094	PhosphoSitePlus	COSMIC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P12980	LYL1	P27361	MAPK3	S36	P32A	32	Missense	distal	-4	no	17.023	16.918	PhosphoSitePlus	COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P12980	LYL1	P27361	MAPK3	S36	A35D	35	Missense	proximal	-1	no	17.023	17.110	PhosphoSitePlus	COSMIC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P12980	LYL1	P27361	MAPK3	S52	V45A	45	Missense	distal	-7	no	17.100	17.101	EPSD	COSMIC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P12980	LYL1	P27361	MAPK3	S260	D256N	256	Missense	distal	-4	no	19.473	19.447	EPSD	COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P12980	LYL1	P27361	MAPK3	S276	L275F	275	Missense	proximal	-1	no	18.036	17.920	EPSD	COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P08047	SP1	P27361	MAPK3	S59	S59Y	59	Missense	central	0	yes	16.761	0.000	PhosphoSitePlus;EPSD	COSMIC	9.358	Loss
CMGC_MAPK_ERK1_MAPK3_ST	P08047	SP1	P27361	MAPK3	S73	E72K	72	Missense	proximal	-1	no	14.920	14.890	EPSD	COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P08047	SP1	P27361	MAPK3	S73	N79K	79	Missense	distal	6	no	14.920	14.941	EPSD	COSMIC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P08047	SP1	P27361	MAPK3	T278	T278M	278	Missense	central	0	yes	14.656	0.000	EPSD	COSMIC	9.358	Loss
CMGC_MAPK_ERK1_MAPK3_ST	P08047	SP1	P27361	MAPK3	T453	P458H	458	Missense	distal	5	no	14.945	14.880	EPSD;PhosphoSitePlus	COSMIC;GDSC;CCLE	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P08047	SP1	P27361	MAPK3	T453	R452W	452	Missense	proximal	-1	no	14.945	14.706	EPSD;PhosphoSitePlus	COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P08047	SP1	P27361	MAPK3	S661	R654M	654	Missense	distal	-7	no	10.288	10.410	EPSD	COSMIC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P08047	SP1	P27361	MAPK3	S661	R654G	654	Missense	distal	-7	no	10.288	10.243	EPSD	COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P08047	SP1	P27361	MAPK3	T739	T739P	739	Missense	central	0	yes	15.700	0.000	EPSD;PhosphoSitePlus	COSMIC	9.358	Loss
CMGC_MAPK_ERK1_MAPK3_ST	P08047	SP1	P27361	MAPK3	T739	T746P	746	Missense	distal	7	no	15.700	15.659	EPSD;PhosphoSitePlus	COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P08047	SP1	P27361	MAPK3	T739	S732L	732	Missense	distal	-7	no	15.700	15.844	EPSD;PhosphoSitePlus	COSMIC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P08047	SP1	P27361	MAPK3	T745	T746P	746	Missense	proximal	1	no	6.461	15.338	EPSD	COSMIC	9.358	Gain
CMGC_MAPK_ERK1_MAPK3_ST	P55211	CASP9	P27361	MAPK3	S87	S87L	87	Missense	central	0	yes	12.012	0.000	EPSD	COSMIC;GDSC;CCLE	9.358	Loss
CMGC_MAPK_ERK1_MAPK3_ST	P55211	CASP9	P27361	MAPK3	S87	R90H	90	Missense	distal	3	no	12.012	12.020	EPSD	COSMIC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P55211	CASP9	P27361	MAPK3	T107	T107A	107	Missense	central	0	yes	14.149	0.000	EPSD	COSMIC	9.358	Loss
CMGC_MAPK_ERK1_MAPK3_ST	P55211	CASP9	P27361	MAPK3	T107	V109L	109	Missense	proximal	2	no	14.149	14.151	EPSD	COSMIC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P55211	CASP9	P27361	MAPK3	T125	T125P	125	Missense	central	0	yes	16.610	0.000	PhosphoSitePlus	COSMIC	9.358	Loss
CMGC_MAPK_ERK1_MAPK3_ST	P55211	CASP9	P27361	MAPK3	S302	E297G	297	Missense	distal	-5	no	16.569	16.560	EPSD	COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P55211	CASP9	P27361	MAPK3	S302	G295V	295	Missense	distal	-7	no	16.569	16.680	EPSD	COSMIC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P55211	CASP9	P27361	MAPK3	S307	S310I	310	Missense	distal	3	no	16.881	16.830	EPSD	COSMIC;CCLE	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P55211	CASP9	P27361	MAPK3	T317	P318S	318	Missense	proximal	1	no	15.422	6.368	EPSD	COSMIC	9.358	Loss
CMGC_MAPK_ERK1_MAPK3_ST	P55211	CASP9	P27361	MAPK3	T317	S310I	310	Missense	distal	-7	no	15.422	15.613	EPSD	COSMIC;CCLE	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	O43561	LAT	P27361	MAPK3	S74	S69A	69	Missense	distal	-5	no	9.977	9.878	EPSD	COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	O43561	LAT	P27361	MAPK3	S74	P76S	76	Missense	proximal	2	no	9.977	9.979	EPSD	COSMIC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	O43561	LAT	P27361	MAPK3	S84	S84F	84	Missense	central	0	yes	17.347	0.000	EPSD	COSMIC	9.358	Loss
CMGC_MAPK_ERK1_MAPK3_ST	O43561	LAT	P27361	MAPK3	S84	P85S	85	Missense	proximal	1	no	17.347	8.293	EPSD	COSMIC	9.358	Loss
CMGC_MAPK_ERK1_MAPK3_ST	O43561	LAT	P27361	MAPK3	T94	S96I	96	Missense	proximal	2	no	14.599	14.564	EPSD	COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	O43561	LAT	P27361	MAPK3	T94	T94M	94	Missense	central	0	yes	14.599	0.000	EPSD	COSMIC	9.358	Loss
CMGC_MAPK_ERK1_MAPK3_ST	O43561	LAT	P27361	MAPK3	T94	R93Q	93	Missense	proximal	-1	no	14.599	14.560	EPSD	COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	O43561	LAT	P27361	MAPK3	T94	S97F	97	Missense	distal	3	no	14.599	14.535	EPSD	COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	O43561	LAT	P27361	MAPK3	T94	P95S	95	Missense	proximal	1	no	14.599	5.546	EPSD	COSMIC	9.358	Loss
CMGC_MAPK_ERK1_MAPK3_ST	O43561	LAT	P27361	MAPK3	T94	R98W	98	Missense	distal	4	no	14.599	14.132	EPSD	COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	O43561	LAT	P27361	MAPK3	S96	S96I	96	Missense	central	0	yes	9.599	0.000	EPSD	COSMIC	9.358	Loss
CMGC_MAPK_ERK1_MAPK3_ST	O43561	LAT	P27361	MAPK3	S96	G103A	103	Missense	distal	7	no	9.599	9.806	EPSD	COSMIC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	O43561	LAT	P27361	MAPK3	S96	T94M	94	Missense	proximal	-2	no	9.599	7.831	EPSD	COSMIC	9.358	Loss
CMGC_MAPK_ERK1_MAPK3_ST	O43561	LAT	P27361	MAPK3	S96	R93Q	93	Missense	distal	-3	no	9.599	9.592	EPSD	COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	O43561	LAT	P27361	MAPK3	S96	S97F	97	Missense	proximal	1	no	9.599	12.439	EPSD	COSMIC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	O43561	LAT	P27361	MAPK3	S96	P95S	95	Missense	proximal	-1	no	9.599	9.593	EPSD	COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	O43561	LAT	P27361	MAPK3	S96	R98W	98	Missense	proximal	2	no	9.599	9.539	EPSD	COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	O43561	LAT	P27361	MAPK3	S97	R98W	98	Missense	proximal	1	no	9.104	10.701	EPSD	COSMIC	9.358	Gain
CMGC_MAPK_ERK1_MAPK3_ST	O43561	LAT	P27361	MAPK3	T184	R188W	188	Missense	distal	4	no	13.929	13.461	EPSD	COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	O43561	LAT	P27361	MAPK3	T184	A181S	181	Missense	distal	-3	no	13.929	14.020	EPSD	COSMIC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	O43561	LAT	P27361	MAPK3	T184	R188L	188	Missense	distal	4	no	13.929	13.872	EPSD	COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	O43561	LAT	P27361	MAPK3	S240	E246D	246	Missense	distal	6	no	9.498	9.453	EPSD	COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	O43561	LAT	P27361	MAPK3	S240	Q242K	242	Missense	proximal	2	no	9.498	9.504	EPSD	COSMIC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	O43561	LAT	P27361	MAPK3	S240	L239M	239	Missense	proximal	-1	no	9.498	9.431	EPSD	COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	O43561	LAT	P27361	MAPK3	S240	A244V	244	Missense	distal	4	no	9.498	9.606	EPSD	COSMIC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	O43561	LAT	P27361	MAPK3	S240	P236L	236	Missense	distal	-4	no	9.498	9.385	EPSD	COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	O43561	LAT	P27361	MAPK3	S241	E246D	246	Missense	distal	5	no	10.504	10.486	EPSD	COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	O43561	LAT	P27361	MAPK3	S241	Q242K	242	Missense	proximal	1	no	10.504	1.295	EPSD	COSMIC	9.358	Loss
CMGC_MAPK_ERK1_MAPK3_ST	O43561	LAT	P27361	MAPK3	S241	L239M	239	Missense	proximal	-2	no	10.504	9.134	EPSD	COSMIC	9.358	Loss
CMGC_MAPK_ERK1_MAPK3_ST	O43561	LAT	P27361	MAPK3	S241	A244V	244	Missense	distal	3	no	10.504	10.511	EPSD	COSMIC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	O43561	LAT	P27361	MAPK3	S241	P236L	236	Missense	distal	-5	no	10.504	10.450	EPSD	COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q15788	NCOA1	P27361	MAPK3	S97	V94I	94	Missense	distal	-3	no	9.649	9.610	EPSD	COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q15788	NCOA1	P27361	MAPK3	S97	D93N	93	Missense	distal	-4	no	9.649	9.623	EPSD	COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q15788	NCOA1	P27361	MAPK3	S97	D92Y	92	Missense	distal	-5	no	9.649	9.620	EPSD	COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q15788	NCOA1	P27361	MAPK3	S325	F330L	330	Missense	distal	5	no	18.757	18.911	EPSD	COSMIC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q15788	NCOA1	P27361	MAPK3	S325	R320C	320	Missense	distal	-5	no	18.757	18.641	EPSD	COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q15788	NCOA1	P27361	MAPK3	S325	S327F	327	Missense	proximal	2	no	18.757	18.707	EPSD	COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q15788	NCOA1	P27361	MAPK3	S325	P326L	326	Missense	proximal	1	no	18.757	9.719	EPSD	COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q15788	NCOA1	P27361	MAPK3	S372	P373S	373	Missense	proximal	1	no	16.818	7.765	EPSD	COSMIC;GDSC;CCLE	9.358	Loss
CMGC_MAPK_ERK1_MAPK3_ST	Q15788	NCOA1	P27361	MAPK3	S372	D365N	365	Missense	distal	-7	no	16.818	16.843	EPSD	COSMIC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q15788	NCOA1	P27361	MAPK3	S372	S372G	372	Missense	central	0	yes	16.818	0.000	EPSD	COSMIC	9.358	Loss
CMGC_MAPK_ERK1_MAPK3_ST	Q15788	NCOA1	P27361	MAPK3	S517	S523G	523	Missense	distal	6	no	16.656	16.423	EPSD	COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q15788	NCOA1	P27361	MAPK3	S558	S557I	557	Missense	proximal	-1	no	14.632	14.501	EPSD	COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q15788	NCOA1	P27361	MAPK3	S603	D604G	604	Missense	proximal	1	no	9.461	6.523	EPSD	COSMIC	9.358	Loss
CMGC_MAPK_ERK1_MAPK3_ST	Q15788	NCOA1	P27361	MAPK3	S679	G674S	674	Missense	distal	-5	no	10.883	10.927	EPSD	COSMIC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q15788	NCOA1	P27361	MAPK3	S679	S682L	682	Missense	distal	3	no	10.883	10.851	EPSD	COSMIC;GDSC;CCLE	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q15788	NCOA1	P27361	MAPK3	S679	P677L	677	Missense	proximal	-2	no	10.883	9.499	EPSD	COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q15788	NCOA1	P27361	MAPK3	S698	R692W	692	Missense	distal	-6	no	15.369	14.847	EPSD	COSMIC;GDSC;CCLE	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q15788	NCOA1	P27361	MAPK3	T789	P790S	790	Missense	proximal	1	no	14.106	5.053	EPSD	COSMIC	9.358	Loss
CMGC_MAPK_ERK1_MAPK3_ST	Q15788	NCOA1	P27361	MAPK3	T979	T979M	979	Missense	central	0	yes	15.913	0.000	EPSD	COSMIC;GDSC;CCLE	9.358	Loss
CMGC_MAPK_ERK1_MAPK3_ST	Q15788	NCOA1	P27361	MAPK3	T979	E986K	986	Missense	distal	7	no	15.913	15.984	EPSD	COSMIC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q15788	NCOA1	P27361	MAPK3	T979	M984K	984	Missense	distal	5	no	15.913	16.152	EPSD	COSMIC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q15788	NCOA1	P27361	MAPK3	S997	S999T	999	Missense	proximal	2	no	16.555	16.544	EPSD	COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q15788	NCOA1	P27361	MAPK3	S997	Y995H	995	Missense	proximal	-2	no	16.555	16.637	EPSD	COSMIC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q15788	NCOA1	P27361	MAPK3	S997	Y991N	991	Missense	distal	-6	no	16.555	16.686	EPSD	COSMIC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q15788	NCOA1	P27361	MAPK3	S997	P994S	994	Missense	distal	-3	no	16.555	16.547	EPSD	COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q15788	NCOA1	P27361	MAPK3	S999	Y995H	995	Missense	distal	-4	no	15.214	15.254	EPSD	COSMIC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q15788	NCOA1	P27361	MAPK3	S999	P994S	994	Missense	distal	-5	no	15.214	15.219	EPSD	COSMIC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q15788	NCOA1	P27361	MAPK3	S1006	R1013S	1013	Missense	distal	7	no	15.764	15.595	EPSD	COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q15788	NCOA1	P27361	MAPK3	S1006	S999T	999	Missense	distal	-7	no	15.764	15.841	EPSD	COSMIC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q15788	NCOA1	P27361	MAPK3	T1026	T1020A	1020	Missense	distal	-6	no	13.828	13.680	EPSD	COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q15788	NCOA1	P27361	MAPK3	T1026	M1021T	1021	Missense	distal	-5	no	13.828	13.931	EPSD	COSMIC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q15788	NCOA1	P27361	MAPK3	T1026	R1029G	1029	Missense	distal	3	no	13.828	13.835	EPSD	COSMIC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q15788	NCOA1	P27361	MAPK3	S1033	R1029G	1029	Missense	distal	-4	no	14.922	14.960	EPSD	COSMIC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q15788	NCOA1	P27361	MAPK3	T1099	N1105S	1105	Missense	distal	6	no	13.844	14.073	EPSD	COSMIC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q15788	NCOA1	P27361	MAPK3	T1099	P1100L	1100	Missense	proximal	1	no	13.844	4.806	EPSD	COSMIC	9.358	Loss
CMGC_MAPK_ERK1_MAPK3_ST	Q15788	NCOA1	P27361	MAPK3	T1099	P1100T	1100	Missense	proximal	1	no	13.844	4.967	EPSD	COSMIC	9.358	Loss
CMGC_MAPK_ERK1_MAPK3_ST	Q15788	NCOA1	P27361	MAPK3	T1099	P1100H	1100	Missense	proximal	1	no	13.844	6.088	EPSD	COSMIC	9.358	Loss
CMGC_MAPK_ERK1_MAPK3_ST	Q15788	NCOA1	P27361	MAPK3	T1179	T1175K	1175	Missense	distal	-4	no	17.543	17.517	PhosphoSitePlus;EPSD	COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q15788	NCOA1	P27361	MAPK3	T1179	T1175M	1175	Missense	distal	-4	no	17.543	17.421	PhosphoSitePlus;EPSD	COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q15788	NCOA1	P27361	MAPK3	S1250	P1251H	1251	Missense	proximal	1	no	15.421	7.666	EPSD	COSMIC	9.358	Loss
CMGC_MAPK_ERK1_MAPK3_ST	Q15788	NCOA1	P27361	MAPK3	S1250	P1251L	1251	Missense	proximal	1	no	15.421	6.383	EPSD	COSMIC	9.358	Loss
CMGC_MAPK_ERK1_MAPK3_ST	Q15788	NCOA1	P27361	MAPK3	S1250	N1244S	1244	Missense	distal	-6	no	15.421	15.544	EPSD	COSMIC;GDSC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q15788	NCOA1	P27361	MAPK3	T1271	P1272S	1272	Missense	proximal	1	no	16.115	7.062	EPSD	COSMIC	9.358	Loss
CMGC_MAPK_ERK1_MAPK3_ST	Q15788	NCOA1	P27361	MAPK3	S1279	P1272S	1272	Missense	distal	-7	no	15.028	14.991	EPSD	COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q15788	NCOA1	P27361	MAPK3	T1426	P1420L	1420	Missense	distal	-6	no	20.148	19.901	EPSD	COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q96RK0	CIC	P27361	MAPK3	S12	R6G	6	Missense	distal	-6	no	11.236	11.334	EPSD	COSMIC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q96RK0	CIC	P27361	MAPK3	S12	P10S	10	Missense	proximal	-2	no	11.236	10.160	EPSD	COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q96RK0	CIC	P27361	MAPK3	S105	G107E	107	Missense	proximal	2	no	18.171	18.179	EPSD	COSMIC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q96RK0	CIC	P27361	MAPK3	S105	G109R	109	Missense	distal	4	no	18.171	18.185	EPSD	COSMIC;GDSC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q96RK0	CIC	P27361	MAPK3	S105	P106S	106	Missense	proximal	1	no	18.171	9.118	EPSD	COSMIC	9.358	Loss
CMGC_MAPK_ERK1_MAPK3_ST	Q96RK0	CIC	P27361	MAPK3	S157	A151V	151	Missense	distal	-6	no	15.106	15.092	EPSD	COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q96RK0	CIC	P27361	MAPK3	S157	I155V	155	Missense	proximal	-2	no	15.106	15.290	EPSD	COSMIC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q96RK0	CIC	P27361	MAPK3	S157	S157C	157	Missense	central	0	yes	15.106	0.000	EPSD	COSMIC	9.358	Loss
CMGC_MAPK_ERK1_MAPK3_ST	Q96RK0	CIC	P27361	MAPK3	S157	M156I	156	Missense	proximal	-1	no	15.106	15.130	EPSD	COSMIC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q96RK0	CIC	P27361	MAPK3	S157	I160N	160	Missense	distal	3	no	15.106	15.136	EPSD	COSMIC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q96RK0	CIC	P27361	MAPK3	S157	L162F	162	Missense	distal	5	no	15.106	14.952	EPSD	COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q96RK0	CIC	P27361	MAPK3	S157	P158L	158	Missense	proximal	1	no	15.106	6.068	EPSD	COSMIC	9.358	Loss
CMGC_MAPK_ERK1_MAPK3_ST	Q96RK0	CIC	P27361	MAPK3	S191	R195Q	195	Missense	distal	4	no	15.426	15.381	EPSD	COSMIC;GDSC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q96RK0	CIC	P27361	MAPK3	S191	R190C	190	Missense	proximal	-1	no	15.426	15.241	EPSD	COSMIC;CCLE	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q96RK0	CIC	P27361	MAPK3	S349	A354S	354	Missense	distal	5	no	9.953	10.208	EPSD	COSMIC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q96RK0	CIC	P27361	MAPK3	S349	R351W	351	Missense	proximal	2	no	9.953	9.893	EPSD	COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q96RK0	CIC	P27361	MAPK3	S349	R353Q	353	Missense	distal	4	no	9.953	9.909	EPSD	COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q96RK0	CIC	P27361	MAPK3	S349	A350V	350	Missense	proximal	1	no	9.953	9.770	EPSD	COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q96RK0	CIC	P27361	MAPK3	S496	S501Y	501	Missense	distal	5	no	17.896	17.680	EPSD	COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q96RK0	CIC	P27361	MAPK3	S496	P497S	497	Missense	proximal	1	no	17.896	8.843	EPSD	COSMIC	9.358	Loss
CMGC_MAPK_ERK1_MAPK3_ST	Q96RK0	CIC	P27361	MAPK3	S496	R500H	500	Missense	distal	4	no	17.896	17.902	EPSD	COSMIC;GDSC;CCLE	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q96RK0	CIC	P27361	MAPK3	S502	P509L	509	Missense	distal	7	no	10.102	10.295	EPSD	COSMIC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q96RK0	CIC	P27361	MAPK3	S502	P509S	509	Missense	distal	7	no	10.102	10.025	EPSD	COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q96RK0	CIC	P27361	MAPK3	S502	R507H	507	Missense	distal	5	no	10.102	10.138	EPSD	COSMIC;GDSC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q96RK0	CIC	P27361	MAPK3	S502	S501Y	501	Missense	proximal	-1	no	10.102	10.026	EPSD	COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q96RK0	CIC	P27361	MAPK3	S502	P497S	497	Missense	distal	-5	no	10.102	10.107	EPSD	COSMIC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q96RK0	CIC	P27361	MAPK3	S502	R500H	500	Missense	proximal	-2	no	10.102	10.275	EPSD	COSMIC;GDSC;CCLE	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q96RK0	CIC	P27361	MAPK3	S502	P508H	508	Missense	distal	6	no	10.102	10.009	EPSD	COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q96RK0	CIC	P27361	MAPK3	S538	S535F	535	Missense	distal	-3	no	15.087	14.945	EPSD	COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q96RK0	CIC	P27361	MAPK3	S538	A536V	536	Missense	proximal	-2	no	15.087	15.784	EPSD	COSMIC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q96RK0	CIC	P27361	MAPK3	S538	A531T	531	Missense	distal	-7	no	15.087	15.013	EPSD	COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q96RK0	CIC	P27361	MAPK3	S538	P532L	532	Missense	distal	-6	no	15.087	14.840	EPSD	COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q96RK0	CIC	P27361	MAPK3	S538	S538L	538	Missense	central	0	yes	15.087	0.000	EPSD	COSMIC	9.358	Loss
CMGC_MAPK_ERK1_MAPK3_ST	Q96RK0	CIC	P27361	MAPK3	S538	A544P	544	Missense	distal	6	no	15.087	15.483	EPSD	COSMIC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q96RK0	CIC	P27361	MAPK3	S543	A544P	544	Missense	proximal	1	no	7.696	16.936	EPSD	COSMIC	9.358	Gain
CMGC_MAPK_ERK1_MAPK3_ST	Q96RK0	CIC	P27361	MAPK3	T583	A578V	578	Missense	distal	-5	no	16.618	16.641	EPSD	COSMIC;GDSC;CCLE	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q96RK0	CIC	P27361	MAPK3	S700	A699V	699	Missense	proximal	-1	no	15.564	15.614	EPSD	COSMIC;GDSC;CCLE	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q96RK0	CIC	P27361	MAPK3	S700	T693A	693	Missense	distal	-7	no	15.564	15.638	EPSD	COSMIC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q96RK0	CIC	P27361	MAPK3	S700	P701S	701	Missense	proximal	1	no	15.564	6.511	EPSD	COSMIC	9.358	Loss
CMGC_MAPK_ERK1_MAPK3_ST	Q96RK0	CIC	P27361	MAPK3	S700	A697T	697	Missense	distal	-3	no	15.564	15.626	EPSD	COSMIC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q96RK0	CIC	P27361	MAPK3	S700	R696W	696	Missense	distal	-4	no	15.564	15.357	EPSD	COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q96RK0	CIC	P27361	MAPK3	S700	A699T	699	Missense	proximal	-1	no	15.564	15.667	EPSD	COSMIC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q96RK0	CIC	P27361	MAPK3	S700	A705T	705	Missense	distal	5	no	15.564	15.684	EPSD	COSMIC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q96RK0	CIC	P27361	MAPK3	S721	G720V	720	Missense	proximal	-1	no	16.522	16.504	EPSD	COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q96RK0	CIC	P27361	MAPK3	S721	G714V	714	Missense	distal	-7	no	16.522	16.633	EPSD	COSMIC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q96RK0	CIC	P27361	MAPK3	S721	R716W	716	Missense	distal	-5	no	16.522	16.368	EPSD	COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q96RK0	CIC	P27361	MAPK3	S721	S726R	726	Missense	distal	5	no	16.522	16.378	EPSD	COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q96RK0	CIC	P27361	MAPK3	S721	S721F	721	Missense	central	0	yes	16.522	0.000	EPSD	COSMIC	9.358	Loss
CMGC_MAPK_ERK1_MAPK3_ST	Q96RK0	CIC	P27361	MAPK3	S721	S721C	721	Missense	central	0	yes	16.522	0.000	EPSD	COSMIC	9.358	Loss
CMGC_MAPK_ERK1_MAPK3_ST	Q96RK0	CIC	P27361	MAPK3	S739	P742S	742	Missense	distal	3	no	15.295	15.290	EPSD	COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q96RK0	CIC	P27361	MAPK3	S739	K732Q	732	Missense	distal	-7	no	15.295	15.293	EPSD	COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q96RK0	CIC	P27361	MAPK3	S904	A900V	900	Missense	distal	-4	no	16.255	16.235	EPSD	COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q96RK0	CIC	P27361	MAPK3	S904	P897R	897	Missense	distal	-7	no	16.255	16.301	EPSD	COSMIC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q96RK0	CIC	P27361	MAPK3	S904	P911S	911	Missense	distal	7	no	16.255	16.178	EPSD	COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q96RK0	CIC	P27361	MAPK3	S904	P911L	911	Missense	distal	7	no	16.255	16.448	EPSD	COSMIC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q96RK0	CIC	P27361	MAPK3	S946	P943S	943	Missense	distal	-3	no	16.358	16.349	EPSD	COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q96RK0	CIC	P27361	MAPK3	S946	F949L	949	Missense	distal	3	no	16.358	16.390	EPSD	COSMIC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q96RK0	CIC	P27361	MAPK3	S946	S946I	946	Missense	central	0	yes	16.358	0.000	EPSD	COSMIC	9.358	Loss
CMGC_MAPK_ERK1_MAPK3_ST	Q96RK0	CIC	P27361	MAPK3	S946	V945M	945	Missense	proximal	-1	no	16.358	16.287	EPSD	COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q96RK0	CIC	P27361	MAPK3	S982	P987S	987	Missense	distal	5	no	19.417	19.460	EPSD	COSMIC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q96RK0	CIC	P27361	MAPK3	S982	P983S	983	Missense	proximal	1	no	19.417	10.364	EPSD	COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q96RK0	CIC	P27361	MAPK3	S982	L986V	986	Missense	distal	4	no	19.417	19.397	EPSD	COSMIC;GDSC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q96RK0	CIC	P27361	MAPK3	S982	P980L	980	Missense	proximal	-2	no	19.417	18.033	EPSD	COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q96RK0	CIC	P27361	MAPK3	T1145	P1146L	1146	Missense	proximal	1	no	15.413	6.375	EPSD	COSMIC;GDSC	9.358	Loss
CMGC_MAPK_ERK1_MAPK3_ST	Q96RK0	CIC	P27361	MAPK3	T1145	A1147V	1147	Missense	proximal	2	no	15.413	15.426	EPSD	COSMIC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q96RK0	CIC	P27361	MAPK3	T1145	P1141S	1141	Missense	distal	-4	no	15.413	15.440	EPSD	COSMIC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q96RK0	CIC	P27361	MAPK3	T1145	P1148L	1148	Missense	distal	3	no	15.413	15.376	EPSD	COSMIC;GDSC;CCLE	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q96RK0	CIC	P27361	MAPK3	T1145	P1138L	1138	Missense	distal	-7	no	15.413	15.520	EPSD	COSMIC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q96RK0	CIC	P27361	MAPK3	T1145	P1141T	1141	Missense	distal	-4	no	15.413	15.382	EPSD	COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q96RK0	CIC	P27361	MAPK3	T1145	A1142T	1142	Missense	distal	-3	no	15.413	15.474	EPSD	COSMIC;GDSC;CCLE	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q96RK0	CIC	P27361	MAPK3	S1150	P1146L	1146	Missense	distal	-4	no	18.693	18.580	EPSD	COSMIC;GDSC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q96RK0	CIC	P27361	MAPK3	S1150	A1147V	1147	Missense	distal	-3	no	18.693	18.712	EPSD	COSMIC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q96RK0	CIC	P27361	MAPK3	S1150	P1148L	1148	Missense	proximal	-2	no	18.693	17.309	EPSD	COSMIC;GDSC;CCLE	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q96RK0	CIC	P27361	MAPK3	S1150	A1155T	1155	Missense	distal	5	no	18.693	18.812	EPSD	COSMIC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q96RK0	CIC	P27361	MAPK3	S1173	P1177H	1177	Missense	distal	4	no	16.957	16.866	EPSD	COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q96RK0	CIC	P27361	MAPK3	S1173	P1174L	1174	Missense	proximal	1	no	16.957	7.919	EPSD	COSMIC	9.358	Loss
CMGC_MAPK_ERK1_MAPK3_ST	Q96RK0	CIC	P27361	MAPK3	S1221	E1222Q	1222	Missense	proximal	1	no	8.698	10.002	EPSD	COSMIC	9.358	Gain
CMGC_MAPK_ERK1_MAPK3_ST	Q96RK0	CIC	P27361	MAPK3	T1228	P1230S	1230	Missense	proximal	2	no	15.870	15.872	EPSD	COSMIC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q96RK0	CIC	P27361	MAPK3	T1228	P1234L	1234	Missense	distal	6	no	15.870	15.644	EPSD	COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q96RK0	CIC	P27361	MAPK3	T1228	P1229A	1229	Missense	proximal	1	no	15.870	6.631	EPSD	COSMIC	9.358	Loss
CMGC_MAPK_ERK1_MAPK3_ST	Q96RK0	CIC	P27361	MAPK3	T1228	T1228I	1228	Missense	central	0	yes	15.870	0.000	EPSD	COSMIC	9.358	Loss
CMGC_MAPK_ERK1_MAPK3_ST	Q96RK0	CIC	P27361	MAPK3	T1228	P1234S	1234	Missense	distal	6	no	15.870	16.000	EPSD	COSMIC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q96RK0	CIC	P27361	MAPK3	T1228	E1222Q	1222	Missense	distal	-6	no	15.870	15.736	EPSD	COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q96RK0	CIC	P27361	MAPK3	T1228	P1227A	1227	Missense	proximal	-1	no	15.870	15.731	EPSD	COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q96RK0	CIC	P27361	MAPK3	T1228	E1222G	1222	Missense	distal	-6	no	15.870	15.824	EPSD	COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q96RK0	CIC	P27361	MAPK3	T1228	P1232L	1232	Missense	distal	4	no	15.870	15.716	EPSD	COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q96RK0	CIC	P27361	MAPK3	T1240	P1236S	1236	Missense	distal	-4	no	16.065	16.092	EPSD	COSMIC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q96RK0	CIC	P27361	MAPK3	T1240	P1234L	1234	Missense	distal	-6	no	16.065	15.818	EPSD	COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q96RK0	CIC	P27361	MAPK3	T1240	W1239R	1239	Missense	proximal	-1	no	16.065	16.303	EPSD	COSMIC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q96RK0	CIC	P27361	MAPK3	T1240	T1242R	1242	Missense	proximal	2	no	16.065	16.064	EPSD	COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q96RK0	CIC	P27361	MAPK3	T1240	P1234S	1234	Missense	distal	-6	no	16.065	16.149	EPSD	COSMIC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q96RK0	CIC	P27361	MAPK3	T1240	T1240R	1240	Missense	central	0	yes	16.065	0.000	EPSD	COSMIC	9.358	Loss
CMGC_MAPK_ERK1_MAPK3_ST	Q96RK0	CIC	P27361	MAPK3	S1246	P1248L	1248	Missense	proximal	2	no	18.368	18.347	EPSD	COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q96RK0	CIC	P27361	MAPK3	S1246	W1239R	1239	Missense	distal	-7	no	18.368	18.122	EPSD	COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q96RK0	CIC	P27361	MAPK3	S1246	P1248S	1248	Missense	proximal	2	no	18.368	18.370	EPSD	COSMIC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q96RK0	CIC	P27361	MAPK3	S1246	T1242R	1242	Missense	distal	-4	no	18.368	18.349	EPSD	COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q96RK0	CIC	P27361	MAPK3	S1246	T1240R	1240	Missense	distal	-6	no	18.368	18.376	EPSD	COSMIC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q96RK0	CIC	P27361	MAPK3	T1291	P1292S	1292	Missense	proximal	1	no	16.488	7.434	EPSD	COSMIC	9.358	Loss
CMGC_MAPK_ERK1_MAPK3_ST	Q96RK0	CIC	P27361	MAPK3	T1291	P1292L	1292	Missense	proximal	1	no	16.488	7.450	EPSD	COSMIC	9.358	Loss
CMGC_MAPK_ERK1_MAPK3_ST	Q96RK0	CIC	P27361	MAPK3	T1291	P1295S	1295	Missense	distal	4	no	16.488	16.537	EPSD	COSMIC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q96RK0	CIC	P27361	MAPK3	T1291	R1286C	1286	Missense	distal	-5	no	16.488	16.371	EPSD	COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q96RK0	CIC	P27361	MAPK3	T1291	S1294L	1294	Missense	distal	3	no	16.488	16.456	EPSD	COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q96RK0	CIC	P27361	MAPK3	T1291	P1292T	1292	Missense	proximal	1	no	16.488	7.610	EPSD	COSMIC	9.358	Loss
CMGC_MAPK_ERK1_MAPK3_ST	Q96RK0	CIC	P27361	MAPK3	T1291	P1292H	1292	Missense	proximal	1	no	16.488	8.732	EPSD	COSMIC	9.358	Loss
CMGC_MAPK_ERK1_MAPK3_ST	Q96RK0	CIC	P27361	MAPK3	T1291	G1287R	1287	Missense	distal	-4	no	16.488	16.449	EPSD	COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q96RK0	CIC	P27361	MAPK3	T1291	P1293S	1293	Missense	proximal	2	no	16.488	16.490	EPSD	COSMIC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q96RK0	CIC	P27361	MAPK3	T1291	P1290L	1290	Missense	proximal	-1	no	16.488	16.393	EPSD	COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q96RK0	CIC	P27361	MAPK3	T1291	P1290S	1290	Missense	proximal	-1	no	16.488	16.482	EPSD	COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q96RK0	CIC	P27361	MAPK3	S1294	P1292S	1292	Missense	proximal	-2	no	19.937	18.861	EPSD	COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q96RK0	CIC	P27361	MAPK3	S1294	P1292L	1292	Missense	proximal	-2	no	19.937	18.553	EPSD	COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q96RK0	CIC	P27361	MAPK3	S1294	P1295S	1295	Missense	proximal	1	no	19.937	10.884	EPSD	COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q96RK0	CIC	P27361	MAPK3	S1294	S1294L	1294	Missense	central	0	yes	19.937	0.000	EPSD	COSMIC	9.358	Loss
CMGC_MAPK_ERK1_MAPK3_ST	Q96RK0	CIC	P27361	MAPK3	S1294	P1292T	1292	Missense	proximal	-2	no	19.937	18.951	EPSD	COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q96RK0	CIC	P27361	MAPK3	S1294	P1292H	1292	Missense	proximal	-2	no	19.937	18.709	EPSD	COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q96RK0	CIC	P27361	MAPK3	S1294	G1287R	1287	Missense	distal	-7	no	19.937	19.982	EPSD	COSMIC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q96RK0	CIC	P27361	MAPK3	S1294	P1293S	1293	Missense	proximal	-1	no	19.937	19.931	EPSD	COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q96RK0	CIC	P27361	MAPK3	S1294	P1290L	1290	Missense	distal	-4	no	19.937	19.824	EPSD	COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q96RK0	CIC	P27361	MAPK3	S1294	P1290S	1290	Missense	distal	-4	no	19.937	19.965	EPSD	COSMIC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q96RK0	CIC	P27361	MAPK3	T1318	R1313W	1313	Missense	distal	-5	no	14.369	14.215	EPSD	COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q96RK0	CIC	P27361	MAPK3	T1318	P1319L	1319	Missense	proximal	1	no	14.369	5.331	EPSD	COSMIC	9.358	Loss
CMGC_MAPK_ERK1_MAPK3_ST	Q96RK0	CIC	P27361	MAPK3	T1318	G1316R	1316	Missense	proximal	-2	no	14.369	15.085	EPSD	COSMIC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q96RK0	CIC	P27361	MAPK3	T1318	G1316E	1316	Missense	proximal	-2	no	14.369	14.839	EPSD	COSMIC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q96RK0	CIC	P27361	MAPK3	S1373	E1368Q	1368	Missense	distal	-5	no	15.892	15.873	EPSD	COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q96RK0	CIC	P27361	MAPK3	S1373	T1375I	1375	Missense	proximal	2	no	15.892	15.868	EPSD	COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q96RK0	CIC	P27361	MAPK3	S1373	R1366W	1366	Missense	distal	-7	no	15.892	16.138	EPSD	COSMIC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q96RK0	CIC	P27361	MAPK3	S1373	S1378P	1378	Missense	distal	5	no	15.892	15.849	EPSD	COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q96RK0	CIC	P27361	MAPK3	S1382	R1384Q	1384	Missense	proximal	2	no	14.315	14.306	EPSD	COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q96RK0	CIC	P27361	MAPK3	S1382	S1382A	1382	Missense	central	0	yes	14.315	0.000	EPSD	COSMIC	9.358	Loss
CMGC_MAPK_ERK1_MAPK3_ST	Q96RK0	CIC	P27361	MAPK3	S1382	S1382L	1382	Missense	central	0	yes	14.315	0.000	EPSD	COSMIC	9.358	Loss
CMGC_MAPK_ERK1_MAPK3_ST	Q96RK0	CIC	P27361	MAPK3	S1382	T1375I	1375	Missense	distal	-7	no	14.315	14.430	EPSD	COSMIC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q96RK0	CIC	P27361	MAPK3	S1382	S1378P	1378	Missense	distal	-4	no	14.315	14.288	EPSD	COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q96RK0	CIC	P27361	MAPK3	S1409	R1412H	1412	Missense	distal	3	no	18.257	18.265	PhosphoSitePlus;EPSD	COSMIC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q96RK0	CIC	P27361	MAPK3	S1409	T1408I	1408	Missense	proximal	-1	no	18.257	18.156	PhosphoSitePlus;EPSD	COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q96RK0	CIC	P27361	MAPK3	S1409	R1416H	1416	Missense	distal	7	no	18.257	18.225	PhosphoSitePlus;EPSD	COSMIC;CCLE	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q96RK0	CIC	P27361	MAPK3	S1409	R1415L	1415	Missense	distal	6	no	18.257	18.142	PhosphoSitePlus;EPSD	COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q96RK0	CIC	P27361	MAPK3	T1426	C1432Y	1432	Missense	distal	6	no	14.172	14.657	EPSD	COSMIC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q96RK0	CIC	P27361	MAPK3	T1426	S1421G	1421	Missense	distal	-5	no	14.172	14.128	EPSD	COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q96RK0	CIC	P27361	MAPK3	T1426	P1427L	1427	Missense	proximal	1	no	14.172	5.134	EPSD	COSMIC	9.358	Loss
CMGC_MAPK_ERK1_MAPK3_ST	Q96RK0	CIC	P27361	MAPK3	T1426	P1424S	1424	Missense	proximal	-2	no	14.172	13.096	EPSD	COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q96RK0	CIC	P27361	MAPK3	T1426	S1419G	1419	Missense	distal	-7	no	14.172	14.210	EPSD	COSMIC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q96RK0	CIC	P27361	MAPK3	T1426	S1422W	1422	Missense	distal	-4	no	14.172	13.887	EPSD	COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q96RK0	CIC	P27361	MAPK3	S1461	S1461F	1461	Missense	central	0	yes	9.672	0.000	EPSD	COSMIC	9.358	Loss
CMGC_MAPK_ERK1_MAPK3_ST	Q96RK0	CIC	P27361	MAPK3	S1461	R1464W	1464	Missense	distal	3	no	9.672	9.594	EPSD	COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q96RK0	CIC	P27361	MAPK3	S1461	L1467M	1467	Missense	distal	6	no	9.672	9.380	EPSD	COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q96RK0	CIC	P27361	MAPK3	S1461	R1465H	1465	Missense	distal	4	no	9.672	9.678	EPSD	COSMIC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q96RK0	CIC	P27361	MAPK3	S1461	R1465C	1465	Missense	distal	4	no	9.672	9.315	EPSD	COSMIC	9.358	Loss
CMGC_MAPK_ERK1_MAPK3_ST	Q96RK0	CIC	P27361	MAPK3	S1461	Y1460H	1460	Missense	proximal	-1	no	9.672	9.710	EPSD	COSMIC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q96RK0	CIC	P27361	MAPK3	S1461	P1459S	1459	Missense	proximal	-2	no	9.672	8.596	EPSD	COSMIC	9.358	Loss
CMGC_MAPK_ERK1_MAPK3_ST	Q96RK0	CIC	P27361	MAPK3	S1461	S1462A	1462	Missense	proximal	1	no	9.672	9.486	EPSD	COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q96RK0	CIC	P27361	MAPK3	S1595	P1599S	1599	Missense	distal	4	no	18.888	18.937	EPSD	COSMIC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q96RK0	CIC	P27361	MAPK3	S1595	E1589Q	1589	Missense	distal	-6	no	18.888	18.753	EPSD	COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q96RK0	CIC	P27361	MAPK3	S1595	S1595F	1595	Missense	central	0	yes	18.888	0.000	EPSD	COSMIC	9.358	Loss
CMGC_MAPK_ERK1_MAPK3_ST	Q96RK0	CIC	P27361	MAPK3	S1595	P1594L	1594	Missense	proximal	-1	no	18.888	18.793	EPSD	COSMIC;CCLE	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q96RK0	CIC	P27361	MAPK3	S1595	P1592H	1592	Missense	distal	-3	no	18.888	18.848	EPSD	COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q96RK0	CIC	P27361	MAPK3	S1595	P1592L	1592	Missense	distal	-3	no	18.888	18.804	EPSD	COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q96RK0	CIC	P27361	MAPK3	S1595	P1592A	1592	Missense	distal	-3	no	18.888	18.788	EPSD	COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q96RK0	CIC	P27361	MAPK3	S1595	P1597S	1597	Missense	proximal	2	no	18.888	18.890	EPSD	COSMIC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P61586	RHOA	P27361	MAPK3	S73	R70K	70	Missense	distal	-3	no	11.807	11.794	EPSD	COSMIC;GDSC;CCLE	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P61586	RHOA	P27361	MAPK3	S73	S73Y	73	Missense	central	0	yes	11.807	0.000	EPSD	COSMIC	9.358	Loss
CMGC_MAPK_ERK1_MAPK3_ST	P61586	RHOA	P27361	MAPK3	S73	I80M	80	Missense	distal	7	no	11.807	11.859	EPSD	COSMIC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P61586	RHOA	P27361	MAPK3	S73	P75L	75	Missense	proximal	2	no	11.807	11.785	EPSD	COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P61586	RHOA	P27361	MAPK3	S73	R68L	68	Missense	distal	-5	no	11.807	11.793	EPSD	COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P61586	RHOA	P27361	MAPK3	S73	D76H	76	Missense	distal	3	no	11.807	11.803	EPSD	COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P61586	RHOA	P27361	MAPK3	S73	D78V	78	Missense	distal	5	no	11.807	11.582	EPSD	COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P61586	RHOA	P27361	MAPK3	S73	P75T	75	Missense	proximal	2	no	11.807	11.798	EPSD	COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P61586	RHOA	P27361	MAPK3	S73	R68H	68	Missense	distal	-5	no	11.807	11.816	EPSD	COSMIC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P61586	RHOA	P27361	MAPK3	S73	L72P	72	Missense	proximal	-1	no	11.807	11.902	EPSD	COSMIC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P61586	RHOA	P27361	MAPK3	S88	S88I	88	Missense	central	0	yes	17.374	0.000	PhosphoSitePlus;EPSD	COSMIC	9.358	Loss
CMGC_MAPK_ERK1_MAPK3_ST	P61586	RHOA	P27361	MAPK3	S88	C83Y	83	Missense	distal	-5	no	17.374	17.472	PhosphoSitePlus;EPSD	COSMIC;CCLE	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P61586	RHOA	P27361	MAPK3	S88	P89L	89	Missense	proximal	1	no	17.374	8.336	PhosphoSitePlus;EPSD	COSMIC	9.358	Loss
CMGC_MAPK_ERK1_MAPK3_ST	P61586	RHOA	P27361	MAPK3	S88	P89R	89	Missense	proximal	1	no	17.374	7.873	PhosphoSitePlus;EPSD	COSMIC	9.358	Loss
CMGC_MAPK_ERK1_MAPK3_ST	P61586	RHOA	P27361	MAPK3	S88	D90N	90	Missense	proximal	2	no	17.374	17.368	PhosphoSitePlus;EPSD	COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P61586	RHOA	P27361	MAPK3	T100	W99R	99	Missense	proximal	-1	no	13.651	13.889	EPSD;PhosphoSitePlus	COSMIC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P61586	RHOA	P27361	MAPK3	T100	H105R	105	Missense	distal	5	no	13.651	13.615	EPSD;PhosphoSitePlus	COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P61586	RHOA	P27361	MAPK3	T100	E102K	102	Missense	proximal	2	no	13.651	13.643	EPSD;PhosphoSitePlus	COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P61586	RHOA	P27361	MAPK3	T100	P101S	101	Missense	proximal	1	no	13.651	4.597	EPSD;PhosphoSitePlus	COSMIC	9.358	Loss
CMGC_MAPK_ERK1_MAPK3_ST	P61586	RHOA	P27361	MAPK3	S160	A161P	161	Missense	proximal	1	no	6.328	15.567	EPSD	COSMIC	9.358	Gain
CMGC_MAPK_ERK1_MAPK3_ST	Q92793	CREBBP	P27361	MAPK3	S19	F22L	22	Missense	distal	3	no	18.110	18.142	EPSD	COSMIC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q92793	CREBBP	P27361	MAPK3	S19	P12H	12	Missense	distal	-7	no	18.110	18.144	EPSD	COSMIC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q92793	CREBBP	P27361	MAPK3	S19	P20T	20	Missense	proximal	1	no	18.110	9.232	EPSD	COSMIC	9.358	Loss
CMGC_MAPK_ERK1_MAPK3_ST	Q92793	CREBBP	P27361	MAPK3	S19	G21D	21	Missense	proximal	2	no	18.110	18.115	EPSD	COSMIC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q92793	CREBBP	P27361	MAPK3	S23	F22L	22	Missense	proximal	-1	no	10.043	10.159	EPSD	COSMIC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q92793	CREBBP	P27361	MAPK3	S23	P20T	20	Missense	distal	-3	no	10.043	10.005	EPSD	COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q92793	CREBBP	P27361	MAPK3	S23	G21D	21	Missense	proximal	-2	no	10.043	10.553	EPSD	COSMIC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q92793	CREBBP	P27361	MAPK3	S93	V89M	89	Missense	distal	-4	no	16.984	16.956	PhosphoSitePlus	COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q92793	CREBBP	P27361	MAPK3	S121	S121I	121	Missense	central	0	yes	14.842	0.000	EPSD	COSMIC	9.358	Loss
CMGC_MAPK_ERK1_MAPK3_ST	Q92793	CREBBP	P27361	MAPK3	S121	S128C	128	Missense	distal	7	no	14.842	15.454	EPSD	COSMIC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q92793	CREBBP	P27361	MAPK3	S121	S116G	116	Missense	distal	-5	no	14.842	14.799	EPSD	COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q92793	CREBBP	P27361	MAPK3	S274	P275L	275	Missense	proximal	1	no	15.055	6.017	EPSD	COSMIC	9.358	Loss
CMGC_MAPK_ERK1_MAPK3_ST	Q92793	CREBBP	P27361	MAPK3	S274	P275S	275	Missense	proximal	1	no	15.055	6.001	EPSD	COSMIC	9.358	Loss
CMGC_MAPK_ERK1_MAPK3_ST	Q92793	CREBBP	P27361	MAPK3	S274	Q278P	278	Missense	distal	4	no	15.055	15.197	EPSD	COSMIC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q92793	CREBBP	P27361	MAPK3	S274	S274N	274	Missense	central	0	yes	15.055	0.000	EPSD	COSMIC	9.358	Loss
CMGC_MAPK_ERK1_MAPK3_ST	Q92793	CREBBP	P27361	MAPK3	S274	G268R	268	Missense	distal	-6	no	15.055	14.957	EPSD	COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q92793	CREBBP	P27361	MAPK3	S274	P275Q	275	Missense	proximal	1	no	15.055	7.111	EPSD	COSMIC	9.358	Loss
CMGC_MAPK_ERK1_MAPK3_ST	Q92793	CREBBP	P27361	MAPK3	S281	P275L	275	Missense	distal	-6	no	10.367	10.120	EPSD	COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q92793	CREBBP	P27361	MAPK3	S281	P275S	275	Missense	distal	-6	no	10.367	10.452	EPSD	COSMIC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q92793	CREBBP	P27361	MAPK3	S281	Q278P	278	Missense	distal	-3	no	10.367	10.421	EPSD	COSMIC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q92793	CREBBP	P27361	MAPK3	S281	S274N	274	Missense	distal	-7	no	10.367	10.434	EPSD	COSMIC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q92793	CREBBP	P27361	MAPK3	S281	P275Q	275	Missense	distal	-6	no	10.367	10.301	EPSD	COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q92793	CREBBP	P27361	MAPK3	S745	R742P	742	Missense	distal	-3	no	14.467	14.514	EPSD	COSMIC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q92793	CREBBP	P27361	MAPK3	S745	M747V	747	Missense	proximal	2	no	14.467	14.485	EPSD	COSMIC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q92793	CREBBP	P27361	MAPK3	S745	V751A	751	Missense	distal	6	no	14.467	14.380	EPSD	COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q92793	CREBBP	P27361	MAPK3	S745	R742L	742	Missense	distal	-3	no	14.467	14.429	EPSD	COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q92793	CREBBP	P27361	MAPK3	T974	V978M	978	Missense	distal	4	no	13.887	13.732	EPSD	COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q92793	CREBBP	P27361	MAPK3	T974	P975S	975	Missense	proximal	1	no	13.887	4.834	EPSD	COSMIC	9.358	Loss
CMGC_MAPK_ERK1_MAPK3_ST	Q92793	CREBBP	P27361	MAPK3	T974	D969H	969	Missense	distal	-5	no	13.887	13.885	EPSD	COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q92793	CREBBP	P27361	MAPK3	T974	A981T	981	Missense	distal	7	no	13.887	13.660	EPSD	COSMIC;GDSC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q92793	CREBBP	P27361	MAPK3	T974	S977L	977	Missense	distal	3	no	13.887	13.855	EPSD	COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q92793	CREBBP	P27361	MAPK3	T974	S967N	967	Missense	distal	-7	no	13.887	13.954	EPSD	COSMIC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q92793	CREBBP	P27361	MAPK3	T974	S977P	977	Missense	distal	3	no	13.887	13.892	EPSD	COSMIC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q92793	CREBBP	P27361	MAPK3	T974	N970I	970	Missense	distal	-4	no	13.887	13.789	EPSD	COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q92793	CREBBP	P27361	MAPK3	S976	S977P	977	Missense	proximal	1	no	7.439	16.493	EPSD	COSMIC	9.358	Gain
CMGC_MAPK_ERK1_MAPK3_ST	Q92793	CREBBP	P27361	MAPK3	S1019	E1016D	1016	Missense	distal	-3	no	9.471	9.468	EPSD	COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q92793	CREBBP	P27361	MAPK3	S1019	M1021I	1021	Missense	proximal	2	no	9.471	9.479	EPSD	COSMIC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q92793	CREBBP	P27361	MAPK3	S1019	G1015V	1015	Missense	distal	-4	no	9.471	9.357	EPSD	COSMIC	9.358	Loss
CMGC_MAPK_ERK1_MAPK3_ST	Q92793	CREBBP	P27361	MAPK3	S1019	E1020V	1020	Missense	proximal	1	no	9.471	9.296	EPSD	COSMIC	9.358	Loss
CMGC_MAPK_ERK1_MAPK3_ST	Q92793	CREBBP	P27361	MAPK3	S1019	E1020G	1020	Missense	proximal	1	no	9.471	7.180	EPSD	COSMIC	9.358	Loss
CMGC_MAPK_ERK1_MAPK3_ST	Q92793	CREBBP	P27361	MAPK3	S1019	E1020Q	1020	Missense	proximal	1	no	9.471	10.775	EPSD	COSMIC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q92793	CREBBP	P27361	MAPK3	S1019	K1014Q	1014	Missense	distal	-5	no	9.471	9.464	EPSD	COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q92793	CREBBP	P27361	MAPK3	S1076	A1071T	1071	Missense	distal	-5	no	17.240	17.323	EPSD	COSMIC;GDSC;CCLE	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q92793	CREBBP	P27361	MAPK3	S1076	S1072F	1072	Missense	distal	-4	no	17.240	17.051	EPSD	COSMIC;GDSC;CCLE	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q92793	CREBBP	P27361	MAPK3	S1076	G1069S	1069	Missense	distal	-7	no	17.240	17.202	EPSD	COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q92793	CREBBP	P27361	MAPK3	S1076	P1080R	1080	Missense	distal	4	no	17.240	17.142	EPSD	COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q92793	CREBBP	P27361	MAPK3	S1076	G1069R	1069	Missense	distal	-7	no	17.240	17.285	EPSD	COSMIC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q92793	CREBBP	P27361	MAPK3	S1076	R1081H	1081	Missense	distal	5	no	17.240	17.275	EPSD	COSMIC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q92793	CREBBP	P27361	MAPK3	S1076	G1069D	1069	Missense	distal	-7	no	17.240	17.245	EPSD	COSMIC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q92793	CREBBP	P27361	MAPK3	S1076	Q1073E	1073	Missense	distal	-3	no	17.240	17.266	EPSD	COSMIC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q92793	CREBBP	P27361	MAPK3	S1076	Q1079H	1079	Missense	distal	3	no	17.240	17.247	EPSD	COSMIC;GDSC;CCLE	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q92793	CREBBP	P27361	MAPK3	S1386	S1388F	1388	Missense	proximal	2	no	9.555	9.505	EPSD	COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q92793	CREBBP	P27361	MAPK3	S1386	S1386C	1386	Missense	central	0	yes	9.555	0.000	EPSD	COSMIC	9.358	Loss
CMGC_MAPK_ERK1_MAPK3_ST	Q92793	CREBBP	P27361	MAPK3	S1386	G1383V	1383	Missense	distal	-3	no	9.555	9.515	EPSD	COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q92793	CREBBP	P27361	MAPK3	S1386	F1379V	1379	Missense	distal	-7	no	9.555	9.485	EPSD	COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q92793	CREBBP	P27361	MAPK3	S1578	E1576K	1576	Missense	proximal	-2	no	9.970	9.276	EPSD	COSMIC	9.358	Loss
CMGC_MAPK_ERK1_MAPK3_ST	Q92793	CREBBP	P27361	MAPK3	S1578	A1571D	1571	Missense	distal	-7	no	9.970	9.863	EPSD	COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q92793	CREBBP	P27361	MAPK3	S1578	S1578C	1578	Missense	central	0	yes	9.970	0.000	EPSD	COSMIC	9.358	Loss
CMGC_MAPK_ERK1_MAPK3_ST	Q92793	CREBBP	P27361	MAPK3	S1578	E1576D	1576	Missense	proximal	-2	no	9.970	10.009	EPSD	COSMIC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q92793	CREBBP	P27361	MAPK3	S1578	S1582R	1582	Missense	distal	4	no	9.970	9.824	EPSD	COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q92793	CREBBP	P27361	MAPK3	S1763	P1759T	1759	Missense	distal	-4	no	17.993	17.962	EPSD	COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q92793	CREBBP	P27361	MAPK3	S1763	Q1765L	1765	Missense	proximal	2	no	17.993	17.992	EPSD	COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q92793	CREBBP	P27361	MAPK3	S1763	Q1756R	1756	Missense	distal	-7	no	17.993	17.994	EPSD	COSMIC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q92793	CREBBP	P27361	MAPK3	S1763	Q1765R	1765	Missense	proximal	2	no	17.993	18.003	EPSD	COSMIC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q92793	CREBBP	P27361	MAPK3	S1884	P1885S	1885	Missense	proximal	1	no	17.209	8.155	EPSD	COSMIC	9.358	Loss
CMGC_MAPK_ERK1_MAPK3_ST	Q92793	CREBBP	P27361	MAPK3	S1884	Q1880L	1880	Missense	distal	-4	no	17.209	17.136	EPSD	COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q92793	CREBBP	P27361	MAPK3	S1884	Q1879E	1879	Missense	distal	-5	no	17.209	17.227	EPSD	COSMIC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q92793	CREBBP	P27361	MAPK3	S1884	Q1879K	1879	Missense	distal	-5	no	17.209	17.216	EPSD	COSMIC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q92793	CREBBP	P27361	MAPK3	S1884	P1889L	1889	Missense	distal	5	no	17.209	16.981	EPSD	COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q92793	CREBBP	P27361	MAPK3	T1892	P1885S	1885	Missense	distal	-7	no	16.726	16.689	EPSD	COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q92793	CREBBP	P27361	MAPK3	T1892	S1898I	1898	Missense	distal	6	no	16.726	16.157	EPSD	COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q92793	CREBBP	P27361	MAPK3	T1892	P1897H	1897	Missense	distal	5	no	16.726	16.661	EPSD	COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q92793	CREBBP	P27361	MAPK3	T1892	P1889L	1889	Missense	distal	-3	no	16.726	16.642	EPSD	COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q92793	CREBBP	P27361	MAPK3	T1892	T1894M	1894	Missense	proximal	2	no	16.726	16.694	EPSD	COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q92793	CREBBP	P27361	MAPK3	T1894	S1898I	1898	Missense	distal	4	no	9.983	9.642	EPSD	COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q92793	CREBBP	P27361	MAPK3	T1894	P1897H	1897	Missense	distal	3	no	9.983	9.964	EPSD	COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q92793	CREBBP	P27361	MAPK3	T1894	P1889L	1889	Missense	distal	-5	no	9.983	9.929	EPSD	COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q92793	CREBBP	P27361	MAPK3	T1894	T1894M	1894	Missense	central	0	yes	9.983	0.000	EPSD	COSMIC	9.358	Loss
CMGC_MAPK_ERK1_MAPK3_ST	Q92793	CREBBP	P27361	MAPK3	T1894	P1900H	1900	Missense	distal	6	no	9.983	9.890	EPSD	COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q92793	CREBBP	P27361	MAPK3	T1899	T1902M	1902	Missense	distal	3	no	18.704	18.655	EPSD	COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q92793	CREBBP	P27361	MAPK3	T1899	S1898I	1898	Missense	proximal	-1	no	18.704	18.572	EPSD	COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q92793	CREBBP	P27361	MAPK3	T1899	Q1904H	1904	Missense	distal	5	no	18.704	18.741	EPSD	COSMIC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q92793	CREBBP	P27361	MAPK3	T1899	P1897H	1897	Missense	proximal	-2	no	18.704	17.476	EPSD	COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q92793	CREBBP	P27361	MAPK3	T1899	P1905L	1905	Missense	distal	6	no	18.704	18.477	EPSD	COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q92793	CREBBP	P27361	MAPK3	T1899	T1894M	1894	Missense	distal	-5	no	18.704	18.601	EPSD	COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q92793	CREBBP	P27361	MAPK3	T1899	P1900H	1900	Missense	proximal	1	no	18.704	10.948	EPSD	COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q92793	CREBBP	P27361	MAPK3	S1912	S1912P	1912	Missense	central	0	yes	16.281	0.000	EPSD	COSMIC	9.358	Loss
CMGC_MAPK_ERK1_MAPK3_ST	Q92793	CREBBP	P27361	MAPK3	S1912	Q1908R	1908	Missense	distal	-4	no	16.281	16.270	EPSD	COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q92793	CREBBP	P27361	MAPK3	S1912	P1911L	1911	Missense	proximal	-1	no	16.281	16.186	EPSD	COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q92793	CREBBP	P27361	MAPK3	S1912	A1907V	1907	Missense	distal	-5	no	16.281	16.304	EPSD	COSMIC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q92793	CREBBP	P27361	MAPK3	S1912	S1912L	1912	Missense	central	0	yes	16.281	0.000	EPSD	COSMIC	9.358	Loss
CMGC_MAPK_ERK1_MAPK3_ST	Q92793	CREBBP	P27361	MAPK3	S1912	A1907T	1907	Missense	distal	-5	no	16.281	16.364	EPSD	COSMIC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q92793	CREBBP	P27361	MAPK3	S1912	P1905L	1905	Missense	distal	-7	no	16.281	16.388	EPSD	COSMIC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q92793	CREBBP	P27361	MAPK3	S1912	P1909L	1909	Missense	distal	-3	no	16.281	16.196	EPSD	COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q92793	CREBBP	P27361	MAPK3	S1912	P1913L	1913	Missense	proximal	1	no	16.281	7.242	EPSD	COSMIC	9.358	Loss
CMGC_MAPK_ERK1_MAPK3_ST	Q92793	CREBBP	P27361	MAPK3	T1990	R1985L	1985	Missense	distal	-5	no	12.179	12.165	EPSD	COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q92793	CREBBP	P27361	MAPK3	T1990	P1997L	1997	Missense	distal	7	no	12.179	12.371	EPSD	COSMIC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q92793	CREBBP	P27361	MAPK3	T1990	P1991L	1991	Missense	proximal	1	no	12.179	3.141	EPSD	COSMIC	9.358	Loss
CMGC_MAPK_ERK1_MAPK3_ST	Q92793	CREBBP	P27361	MAPK3	T1990	R1985H	1985	Missense	distal	-5	no	12.179	12.188	EPSD	COSMIC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q92793	CREBBP	P27361	MAPK3	T1990	A1996V	1996	Missense	distal	6	no	12.179	12.266	EPSD	COSMIC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q92793	CREBBP	P27361	MAPK3	S1993	P1997L	1997	Missense	distal	4	no	9.797	9.642	EPSD	COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q92793	CREBBP	P27361	MAPK3	S1993	P1991L	1991	Missense	proximal	-2	no	9.797	8.413	EPSD	COSMIC	9.358	Loss
CMGC_MAPK_ERK1_MAPK3_ST	Q92793	CREBBP	P27361	MAPK3	S1993	A1996V	1996	Missense	distal	3	no	9.797	9.803	EPSD	COSMIC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q92793	CREBBP	P27361	MAPK3	S2063	V2056M	2056	Missense	distal	-7	no	15.063	15.118	EPSD	COSMIC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q92793	CREBBP	P27361	MAPK3	S2063	S2065N	2065	Missense	proximal	2	no	15.063	15.045	EPSD	COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q92793	CREBBP	P27361	MAPK3	S2076	S2076L	2076	Missense	central	0	yes	16.918	0.000	EPSD	COSMIC;GDSC;CCLE	9.358	Loss
CMGC_MAPK_ERK1_MAPK3_ST	Q92793	CREBBP	P27361	MAPK3	S2078	S2076L	2076	Missense	proximal	-2	no	9.749	9.441	EPSD	COSMIC;GDSC;CCLE	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q92793	CREBBP	P27361	MAPK3	S2079	S2076L	2076	Missense	distal	-3	no	17.643	17.567	EPSD	COSMIC;GDSC;CCLE	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q92793	CREBBP	P27361	MAPK3	S2307	P2311L	2311	Missense	distal	4	no	15.501	15.347	EPSD	COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q92793	CREBBP	P27361	MAPK3	S2307	P2313L	2313	Missense	distal	6	no	15.501	15.275	EPSD	COSMIC;GDSC;CCLE	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q92793	CREBBP	P27361	MAPK3	S2307	G2306V	2306	Missense	proximal	-1	no	15.501	15.483	EPSD	COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q92793	CREBBP	P27361	MAPK3	S2307	S2307F	2307	Missense	central	0	yes	15.501	0.000	EPSD	COSMIC	9.358	Loss
CMGC_MAPK_ERK1_MAPK3_ST	Q92793	CREBBP	P27361	MAPK3	S2307	P2308L	2308	Missense	proximal	1	no	15.501	6.463	EPSD	COSMIC	9.358	Loss
CMGC_MAPK_ERK1_MAPK3_ST	Q92793	CREBBP	P27361	MAPK3	S2315	Q2318E	2318	Missense	distal	3	no	16.838	16.846	EPSD	COSMIC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q92793	CREBBP	P27361	MAPK3	S2315	P2311L	2311	Missense	distal	-4	no	16.838	16.725	EPSD	COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q92793	CREBBP	P27361	MAPK3	S2315	P2313L	2313	Missense	proximal	-2	no	16.838	15.453	EPSD	COSMIC;GDSC;CCLE	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q92793	CREBBP	P27361	MAPK3	S2315	S2322L	2322	Missense	distal	7	no	16.838	17.108	EPSD	COSMIC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q92793	CREBBP	P27361	MAPK3	S2315	P2308L	2308	Missense	distal	-7	no	16.838	16.945	EPSD	COSMIC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q92793	CREBBP	P27361	MAPK3	S2328	Q2324H	2324	Missense	distal	-4	no	9.512	9.516	EPSD	COSMIC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q92793	CREBBP	P27361	MAPK3	S2328	G2323K	2323	Missense	distal	-5	no	9.512	9.509	EPSD	COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q92793	CREBBP	P27361	MAPK3	S2328	A2327V	2327	Missense	proximal	-1	no	9.512	9.562	EPSD	COSMIC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q92793	CREBBP	P27361	MAPK3	S2328	Q2324K	2324	Missense	distal	-4	no	9.512	9.495	EPSD	COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q92793	CREBBP	P27361	MAPK3	S2328	S2322L	2322	Missense	distal	-6	no	9.512	9.181	EPSD	COSMIC	9.358	Loss
CMGC_MAPK_ERK1_MAPK3_ST	Q92793	CREBBP	P27361	MAPK3	S2328	L2330R	2330	Missense	proximal	2	no	9.512	9.523	EPSD	COSMIC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q92793	CREBBP	P27361	MAPK3	S2328	P2331L	2331	Missense	distal	3	no	9.512	9.476	EPSD	COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q92793	CREBBP	P27361	MAPK3	S2328	P2325L	2325	Missense	distal	-3	no	9.512	9.428	EPSD	COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q92793	CREBBP	P27361	MAPK3	S2328	P2331T	2331	Missense	distal	3	no	9.512	9.494	EPSD	COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q92793	CREBBP	P27361	MAPK3	S2345	P2352L	2352	Missense	distal	7	no	15.983	16.176	EPSD	COSMIC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q92793	CREBBP	P27361	MAPK3	S2345	N2341K	2341	Missense	distal	-4	no	15.983	15.961	EPSD	COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q92793	CREBBP	P27361	MAPK3	S2345	P2346L	2346	Missense	proximal	1	no	15.983	6.945	EPSD	COSMIC	9.358	Loss
CMGC_MAPK_ERK1_MAPK3_ST	Q92793	CREBBP	P27361	MAPK3	S2345	S2338C	2338	Missense	distal	-7	no	15.983	16.253	EPSD	COSMIC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q92793	CREBBP	P27361	MAPK3	S2345	S2345F	2345	Missense	central	0	yes	15.983	0.000	EPSD	COSMIC	9.358	Loss
CMGC_MAPK_ERK1_MAPK3_ST	Q92793	CREBBP	P27361	MAPK3	S2351	P2358S	2358	Missense	distal	7	no	15.918	15.841	EPSD	COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q92793	CREBBP	P27361	MAPK3	S2351	P2352L	2352	Missense	proximal	1	no	15.918	6.880	EPSD	COSMIC	9.358	Loss
CMGC_MAPK_ERK1_MAPK3_ST	Q92793	CREBBP	P27361	MAPK3	S2351	P2346L	2346	Missense	distal	-5	no	15.918	15.864	EPSD	COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q92793	CREBBP	P27361	MAPK3	S2351	S2356P	2356	Missense	distal	5	no	15.918	15.875	EPSD	COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q92793	CREBBP	P27361	MAPK3	S2351	R2353W	2353	Missense	proximal	2	no	15.918	15.858	EPSD	COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q92793	CREBBP	P27361	MAPK3	S2351	S2345F	2345	Missense	distal	-6	no	15.918	15.451	EPSD	COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q92793	CREBBP	P27361	MAPK3	S2356	P2358S	2358	Missense	proximal	2	no	9.396	9.398	EPSD	COSMIC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q92793	CREBBP	P27361	MAPK3	S2356	P2352L	2352	Missense	distal	-4	no	9.396	9.284	EPSD	COSMIC	9.358	Loss
CMGC_MAPK_ERK1_MAPK3_ST	Q92793	CREBBP	P27361	MAPK3	S2356	P2363L	2363	Missense	distal	7	no	9.396	9.589	EPSD	COSMIC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q92793	CREBBP	P27361	MAPK3	S2356	S2361F	2361	Missense	distal	5	no	9.396	8.972	EPSD	COSMIC	9.358	Loss
CMGC_MAPK_ERK1_MAPK3_ST	Q92793	CREBBP	P27361	MAPK3	S2356	S2356P	2356	Missense	central	0	yes	9.396	0.000	EPSD	COSMIC	9.358	Loss
CMGC_MAPK_ERK1_MAPK3_ST	Q92793	CREBBP	P27361	MAPK3	S2356	R2353W	2353	Missense	distal	-3	no	9.396	9.229	EPSD	COSMIC	9.358	Loss
CMGC_MAPK_ERK1_MAPK3_ST	Q92793	CREBBP	P27361	MAPK3	S2361	P2358S	2358	Missense	distal	-3	no	10.060	10.052	EPSD	COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q92793	CREBBP	P27361	MAPK3	S2361	P2363L	2363	Missense	proximal	2	no	10.060	10.039	EPSD	COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q92793	CREBBP	P27361	MAPK3	S2361	S2361F	2361	Missense	central	0	yes	10.060	0.000	EPSD	COSMIC	9.358	Loss
CMGC_MAPK_ERK1_MAPK3_ST	Q92793	CREBBP	P27361	MAPK3	S2361	R2366W	2366	Missense	distal	5	no	10.060	9.592	EPSD	COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q92793	CREBBP	P27361	MAPK3	S2361	S2356P	2356	Missense	distal	-5	no	10.060	10.055	EPSD	COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q92793	CREBBP	P27361	MAPK3	S2361	R2366Q	2366	Missense	distal	5	no	10.060	10.059	EPSD	COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q92793	CREBBP	P27361	MAPK3	S2362	P2358S	2358	Missense	distal	-4	no	16.541	16.568	EPSD	COSMIC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q92793	CREBBP	P27361	MAPK3	S2362	P2369T	2369	Missense	distal	7	no	16.541	16.582	EPSD	COSMIC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q92793	CREBBP	P27361	MAPK3	S2362	P2363L	2363	Missense	proximal	1	no	16.541	7.503	EPSD	COSMIC	9.358	Loss
CMGC_MAPK_ERK1_MAPK3_ST	Q92793	CREBBP	P27361	MAPK3	S2362	S2361F	2361	Missense	proximal	-1	no	16.541	16.337	EPSD	COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q92793	CREBBP	P27361	MAPK3	S2362	R2366W	2366	Missense	distal	4	no	16.541	16.073	EPSD	COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q92793	CREBBP	P27361	MAPK3	S2362	S2356P	2356	Missense	distal	-6	no	16.541	16.456	EPSD	COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q92793	CREBBP	P27361	MAPK3	S2362	R2366Q	2366	Missense	distal	4	no	16.541	16.496	EPSD	COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q92793	CREBBP	P27361	MAPK3	S2364	P2358S	2358	Missense	distal	-6	no	17.386	17.471	EPSD	COSMIC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q92793	CREBBP	P27361	MAPK3	S2364	P2369T	2369	Missense	distal	5	no	17.386	17.293	EPSD	COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q92793	CREBBP	P27361	MAPK3	S2364	P2363L	2363	Missense	proximal	-1	no	17.386	17.291	EPSD	COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q92793	CREBBP	P27361	MAPK3	S2364	S2361F	2361	Missense	distal	-3	no	17.386	17.245	EPSD	COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q92793	CREBBP	P27361	MAPK3	S2364	R2366W	2366	Missense	proximal	2	no	17.386	17.326	EPSD	COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q92793	CREBBP	P27361	MAPK3	S2364	R2366Q	2366	Missense	proximal	2	no	17.386	17.377	EPSD	COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q92793	CREBBP	P27361	MAPK3	S2372	S2377L	2377	Missense	distal	5	no	16.983	16.713	EPSD	COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q92793	CREBBP	P27361	MAPK3	S2372	P2369T	2369	Missense	distal	-3	no	16.983	16.945	EPSD	COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q92793	CREBBP	P27361	MAPK3	S2372	S2372W	2372	Missense	central	0	yes	16.983	0.000	EPSD	COSMIC	9.358	Loss
CMGC_MAPK_ERK1_MAPK3_ST	Q92793	CREBBP	P27361	MAPK3	S2372	R2366W	2366	Missense	distal	-6	no	16.983	16.461	EPSD	COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q92793	CREBBP	P27361	MAPK3	S2372	R2366Q	2366	Missense	distal	-6	no	16.983	16.993	EPSD	COSMIC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q92793	CREBBP	P27361	MAPK3	S2372	Q2379H	2379	Missense	distal	7	no	16.983	16.921	EPSD	COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q92793	CREBBP	P27361	MAPK3	S2377	S2377L	2377	Missense	central	0	yes	16.925	0.000	EPSD	COSMIC	9.358	Loss
CMGC_MAPK_ERK1_MAPK3_ST	Q92793	CREBBP	P27361	MAPK3	S2377	H2384R	2384	Missense	distal	7	no	16.925	16.958	EPSD	COSMIC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q92793	CREBBP	P27361	MAPK3	S2377	P2383L	2383	Missense	distal	6	no	16.925	16.698	EPSD	COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q92793	CREBBP	P27361	MAPK3	S2377	S2372W	2372	Missense	distal	-5	no	16.925	16.726	EPSD	COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q92793	CREBBP	P27361	MAPK3	S2377	P2383S	2383	Missense	distal	6	no	16.925	17.055	EPSD	COSMIC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q92793	CREBBP	P27361	MAPK3	S2377	H2384N	2384	Missense	distal	7	no	16.925	16.954	EPSD	COSMIC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q92793	CREBBP	P27361	MAPK3	S2377	Q2379H	2379	Missense	proximal	2	no	16.925	16.932	EPSD	COSMIC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q92793	CREBBP	P27361	MAPK3	S2382	S2377L	2377	Missense	distal	-5	no	16.838	16.779	EPSD	COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q92793	CREBBP	P27361	MAPK3	S2382	H2384R	2384	Missense	proximal	2	no	16.838	16.841	EPSD	COSMIC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q92793	CREBBP	P27361	MAPK3	S2382	P2383L	2383	Missense	proximal	1	no	16.838	7.800	EPSD	COSMIC	9.358	Loss
CMGC_MAPK_ERK1_MAPK3_ST	Q92793	CREBBP	P27361	MAPK3	S2382	P2383S	2383	Missense	proximal	1	no	16.838	7.785	EPSD	COSMIC	9.358	Loss
CMGC_MAPK_ERK1_MAPK3_ST	Q92793	CREBBP	P27361	MAPK3	S2382	H2384N	2384	Missense	proximal	2	no	16.838	16.836	EPSD	COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q92793	CREBBP	P27361	MAPK3	S2382	P2385S	2385	Missense	distal	3	no	16.838	16.834	EPSD	COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q92793	CREBBP	P27361	MAPK3	S2382	Q2379H	2379	Missense	distal	-3	no	16.838	16.852	EPSD	COSMIC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q92793	CREBBP	P27361	MAPK3	T2414	P2415L	2415	Missense	proximal	1	no	16.841	7.803	EPSD	COSMIC	9.358	Loss
CMGC_MAPK_ERK1_MAPK3_ST	Q92793	CREBBP	P27361	MAPK3	T2414	P2410S	2410	Missense	distal	-4	no	16.841	16.868	EPSD	COSMIC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q92793	CREBBP	P27361	MAPK3	T2414	A2419V	2419	Missense	distal	5	no	16.841	16.829	EPSD	COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q92793	CREBBP	P27361	MAPK3	T2414	M2408V	2408	Missense	distal	-6	no	16.841	16.933	EPSD	COSMIC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q92793	CREBBP	P27361	MAPK3	T2414	L2409H	2409	Missense	distal	-5	no	16.841	16.864	EPSD	COSMIC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q92793	CREBBP	P27361	MAPK3	T2414	S2421F	2421	Missense	distal	7	no	16.841	17.332	EPSD	COSMIC;GDSC;CCLE	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q92793	CREBBP	P27361	MAPK3	S2416	P2415L	2415	Missense	proximal	-1	no	11.532	11.437	EPSD	COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q92793	CREBBP	P27361	MAPK3	S2416	P2410S	2410	Missense	distal	-6	no	11.532	11.616	EPSD	COSMIC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q92793	CREBBP	P27361	MAPK3	S2416	A2419V	2419	Missense	distal	3	no	11.532	11.538	EPSD	COSMIC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q92793	CREBBP	P27361	MAPK3	S2416	L2409H	2409	Missense	distal	-7	no	11.532	11.459	EPSD	COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q92793	CREBBP	P27361	MAPK3	S2416	S2421F	2421	Missense	distal	5	no	11.532	11.107	EPSD	COSMIC;GDSC;CCLE	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q92793	CREBBP	P27361	MAPK3	S2422	P2415L	2415	Missense	distal	-7	no	9.858	9.965	EPSD	COSMIC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q92793	CREBBP	P27361	MAPK3	S2422	A2419V	2419	Missense	distal	-3	no	9.858	9.877	EPSD	COSMIC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q92793	CREBBP	P27361	MAPK3	S2422	D2429Y	2429	Missense	distal	7	no	9.858	10.006	EPSD	COSMIC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q92793	CREBBP	P27361	MAPK3	S2422	S2421F	2421	Missense	proximal	-1	no	9.858	9.653	EPSD	COSMIC;GDSC;CCLE	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q92793	CREBBP	P27361	MAPK3	S2425	A2419V	2419	Missense	distal	-6	no	10.188	10.174	EPSD	COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q92793	CREBBP	P27361	MAPK3	S2425	D2429Y	2429	Missense	distal	4	no	10.188	10.091	EPSD	COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q92793	CREBBP	P27361	MAPK3	S2425	S2421F	2421	Missense	distal	-4	no	10.188	9.999	EPSD	COSMIC;GDSC;CCLE	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P32121	ARRB2	P27361	MAPK3	S14	V21M	21	Missense	distal	7	no	16.586	16.718	PhosphoSitePlus;EPSD	COSMIC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P32121	ARRB2	P27361	MAPK3	T276	R283Q	283	Missense	distal	7	no	16.109	16.139	EPSD;PhosphoSitePlus	COSMIC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P32121	ARRB2	P27361	MAPK3	T276	R283W	283	Missense	distal	7	no	16.109	16.685	EPSD;PhosphoSitePlus	COSMIC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P32121	ARRB2	P27361	MAPK3	T276	D281V	281	Missense	distal	5	no	16.109	15.884	EPSD;PhosphoSitePlus	COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P32121	ARRB2	P27361	MAPK3	T276	T276I	276	Missense	central	0	yes	16.109	0.000	EPSD;PhosphoSitePlus	COSMIC	9.358	Loss
CMGC_MAPK_ERK1_MAPK3_ST	Q01196	RUNX1	P27361	MAPK3	T14	T14M	14	Missense	central	0	yes	15.553	0.000	EPSD	COSMIC	9.358	Loss
CMGC_MAPK_ERK1_MAPK3_ST	Q01196	RUNX1	P27361	MAPK3	S17	K24N	24	Missense	distal	7	no	10.932	10.923	EPSD	COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q01196	RUNX1	P27361	MAPK3	S17	P22L	22	Missense	distal	5	no	10.932	10.704	EPSD	COSMIC;CCLE	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q01196	RUNX1	P27361	MAPK3	S17	P22Q	22	Missense	distal	5	no	10.932	10.830	EPSD	COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q01196	RUNX1	P27361	MAPK3	S17	T14M	14	Missense	distal	-3	no	10.932	10.835	EPSD	COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q01196	RUNX1	P27361	MAPK3	T18	K24N	24	Missense	distal	6	no	9.446	9.425	EPSD	COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q01196	RUNX1	P27361	MAPK3	T18	M25K	25	Missense	distal	7	no	9.446	9.171	EPSD	COSMIC	9.358	Loss
CMGC_MAPK_ERK1_MAPK3_ST	Q01196	RUNX1	P27361	MAPK3	T18	P22L	22	Missense	distal	4	no	9.446	9.292	EPSD	COSMIC;CCLE	9.358	Loss
CMGC_MAPK_ERK1_MAPK3_ST	Q01196	RUNX1	P27361	MAPK3	T18	P22Q	22	Missense	distal	4	no	9.446	9.304	EPSD	COSMIC	9.358	Loss
CMGC_MAPK_ERK1_MAPK3_ST	Q01196	RUNX1	P27361	MAPK3	T18	T14M	14	Missense	distal	-4	no	9.446	9.325	EPSD	COSMIC	9.358	Loss
CMGC_MAPK_ERK1_MAPK3_ST	Q01196	RUNX1	P27361	MAPK3	S21	K24N	24	Missense	distal	3	no	17.104	17.107	EPSD	COSMIC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q01196	RUNX1	P27361	MAPK3	S21	M25K	25	Missense	distal	4	no	17.104	17.344	EPSD	COSMIC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q01196	RUNX1	P27361	MAPK3	S21	E27Q	27	Missense	distal	6	no	17.104	16.924	EPSD	COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q01196	RUNX1	P27361	MAPK3	S21	A28E	28	Missense	distal	7	no	17.104	16.862	EPSD	COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q01196	RUNX1	P27361	MAPK3	S21	P22L	22	Missense	proximal	1	no	17.104	8.066	EPSD	COSMIC;CCLE	9.358	Loss
CMGC_MAPK_ERK1_MAPK3_ST	Q01196	RUNX1	P27361	MAPK3	S21	P22Q	22	Missense	proximal	1	no	17.104	9.160	EPSD	COSMIC	9.358	Loss
CMGC_MAPK_ERK1_MAPK3_ST	Q01196	RUNX1	P27361	MAPK3	S21	E27K	27	Missense	distal	6	no	17.104	17.028	EPSD	COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q01196	RUNX1	P27361	MAPK3	S21	T14M	14	Missense	distal	-7	no	17.104	17.232	EPSD	COSMIC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q01196	RUNX1	P27361	MAPK3	S26	E27Q	27	Missense	proximal	1	no	8.677	9.981	EPSD	COSMIC	9.358	Gain
CMGC_MAPK_ERK1_MAPK3_ST	Q01196	RUNX1	P27361	MAPK3	S67	L71M	71	Missense	distal	4	no	17.053	16.878	EPSD	COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q01196	RUNX1	P27361	MAPK3	S67	V63A	63	Missense	distal	-4	no	17.053	17.073	EPSD	COSMIC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q01196	RUNX1	P27361	MAPK3	S67	L62R	62	Missense	distal	-5	no	17.053	17.067	EPSD	COSMIC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q01196	RUNX1	P27361	MAPK3	S67	F70Y	70	Missense	distal	3	no	17.053	17.087	EPSD	COSMIC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q01196	RUNX1	P27361	MAPK3	S67	F70L	70	Missense	distal	3	no	17.053	17.085	EPSD	COSMIC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q01196	RUNX1	P27361	MAPK3	S67	T65A	65	Missense	proximal	-2	no	17.053	15.688	EPSD	COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q01196	RUNX1	P27361	MAPK3	S67	S73F	73	Missense	distal	6	no	17.053	16.339	EPSD	COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q01196	RUNX1	P27361	MAPK3	S67	D66N	66	Missense	proximal	-1	no	17.053	17.051	EPSD	COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q01196	RUNX1	P27361	MAPK3	S67	C72Y	72	Missense	distal	5	no	17.053	17.360	EPSD	COSMIC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q01196	RUNX1	P27361	MAPK3	S67	N69S	69	Missense	proximal	2	no	17.053	17.070	EPSD	COSMIC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q01196	RUNX1	P27361	MAPK3	S67	P68L	68	Missense	proximal	1	no	17.053	8.015	EPSD	COSMIC	9.358	Loss
CMGC_MAPK_ERK1_MAPK3_ST	Q01196	RUNX1	P27361	MAPK3	S67	S67I	67	Missense	central	0	yes	17.053	0.000	EPSD	COSMIC	9.358	Loss
CMGC_MAPK_ERK1_MAPK3_ST	Q01196	RUNX1	P27361	MAPK3	S67	E61K	61	Missense	distal	-6	no	17.053	16.911	EPSD	COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q01196	RUNX1	P27361	MAPK3	S67	S67R	67	Missense	central	0	yes	17.053	0.000	EPSD	COSMIC;CCLE	9.358	Loss
CMGC_MAPK_ERK1_MAPK3_ST	Q01196	RUNX1	P27361	MAPK3	S67	S73C	73	Missense	distal	6	no	17.053	16.186	EPSD	COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q01196	RUNX1	P27361	MAPK3	S67	F70S	70	Missense	distal	3	no	17.053	17.117	EPSD	COSMIC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q01196	RUNX1	P27361	MAPK3	S67	D66Y	66	Missense	proximal	-1	no	17.053	17.023	EPSD	COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q01196	RUNX1	P27361	MAPK3	T84	L85P	85	Missense	proximal	1	no	3.508	12.546	EPSD	COSMIC	9.358	Gain
CMGC_MAPK_ERK1_MAPK3_ST	Q01196	RUNX1	P27361	MAPK3	T147	L148P	148	Missense	proximal	1	no	4.973	14.011	EPSD	COSMIC	9.358	Gain
CMGC_MAPK_ERK1_MAPK3_ST	Q01196	RUNX1	P27361	MAPK3	S193	Q186H	186	Missense	distal	-7	no	10.905	10.895	EPSD	COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q01196	RUNX1	P27361	MAPK3	S193	S199R	199	Missense	distal	6	no	10.905	10.663	EPSD	COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q01196	RUNX1	P27361	MAPK3	S193	R197L	197	Missense	distal	4	no	10.905	10.848	EPSD	COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q01196	RUNX1	P27361	MAPK3	S193	E196G	196	Missense	distal	3	no	10.905	10.903	EPSD	COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q01196	RUNX1	P27361	MAPK3	S193	F194S	194	Missense	proximal	1	no	10.905	8.065	EPSD	COSMIC	9.358	Loss
CMGC_MAPK_ERK1_MAPK3_ST	Q01196	RUNX1	P27361	MAPK3	S193	T187I	187	Missense	distal	-6	no	10.905	10.675	EPSD	COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q01196	RUNX1	P27361	MAPK3	S193	Q186E	186	Missense	distal	-7	no	10.905	10.855	EPSD	COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q01196	RUNX1	P27361	MAPK3	S193	E196K	196	Missense	distal	3	no	10.905	10.894	EPSD	COSMIC;CCLE	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q01196	RUNX1	P27361	MAPK3	S193	S199N	199	Missense	distal	6	no	10.905	10.676	EPSD	COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q01196	RUNX1	P27361	MAPK3	S193	S191T	191	Missense	proximal	-2	no	10.905	10.995	EPSD	COSMIC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q01196	RUNX1	P27361	MAPK3	S212	A208G	208	Missense	distal	-4	no	17.427	17.520	EPSD	COSMIC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q01196	RUNX1	P27361	MAPK3	S212	S212L	212	Missense	central	0	yes	17.427	0.000	EPSD	COSMIC	9.358	Loss
CMGC_MAPK_ERK1_MAPK3_ST	Q01196	RUNX1	P27361	MAPK3	S212	R205Q	205	Missense	distal	-7	no	17.427	17.426	EPSD	COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q01196	RUNX1	P27361	MAPK3	S212	R205L	205	Missense	distal	-7	no	17.427	17.489	EPSD	COSMIC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q01196	RUNX1	P27361	MAPK3	S212	R210K	210	Missense	proximal	-2	no	17.427	16.487	EPSD	COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q01196	RUNX1	P27361	MAPK3	S212	T219M	219	Missense	distal	7	no	17.427	17.759	EPSD	COSMIC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q01196	RUNX1	P27361	MAPK3	S212	A208V	208	Missense	distal	-4	no	17.427	17.407	EPSD	COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q01196	RUNX1	P27361	MAPK3	S212	R205W	205	Missense	distal	-7	no	17.427	17.673	EPSD	COSMIC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q01196	RUNX1	P27361	MAPK3	S212	P218S	218	Missense	distal	6	no	17.427	17.557	EPSD	COSMIC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q01196	RUNX1	P27361	MAPK3	S212	P216L	216	Missense	distal	4	no	17.427	17.272	EPSD	COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q01196	RUNX1	P27361	MAPK3	S212	A208T	208	Missense	distal	-4	no	17.427	17.500	EPSD	COSMIC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q01196	RUNX1	P27361	MAPK3	S212	A217V	217	Missense	distal	5	no	17.427	17.416	EPSD	COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q01196	RUNX1	P27361	MAPK3	S212	R206H	206	Missense	distal	-6	no	17.427	17.422	EPSD	COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q01196	RUNX1	P27361	MAPK3	S212	P218L	218	Missense	distal	6	no	17.427	17.200	EPSD	COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q01196	RUNX1	P27361	MAPK3	S212	V211A	211	Missense	proximal	-1	no	17.427	17.377	EPSD	COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q01196	RUNX1	P27361	MAPK3	S212	M209I	209	Missense	distal	-3	no	17.427	17.443	EPSD	COSMIC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q01196	RUNX1	P27361	MAPK3	T219	L226F	226	Missense	distal	7	no	13.849	14.070	EPSD	COSMIC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q01196	RUNX1	P27361	MAPK3	T219	S212L	212	Missense	distal	-7	no	13.849	13.994	EPSD	COSMIC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q01196	RUNX1	P27361	MAPK3	T219	A224V	224	Missense	distal	5	no	13.849	13.838	EPSD	COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q01196	RUNX1	P27361	MAPK3	T219	R223C	223	Missense	distal	4	no	13.849	13.492	EPSD	COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q01196	RUNX1	P27361	MAPK3	T219	T219M	219	Missense	central	0	yes	13.849	0.000	EPSD	COSMIC	9.358	Loss
CMGC_MAPK_ERK1_MAPK3_ST	Q01196	RUNX1	P27361	MAPK3	T219	S225F	225	Missense	distal	6	no	13.849	13.136	EPSD	COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q01196	RUNX1	P27361	MAPK3	T219	P218S	218	Missense	proximal	-1	no	13.849	13.844	EPSD	COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q01196	RUNX1	P27361	MAPK3	T219	A224T	224	Missense	distal	5	no	13.849	13.969	EPSD	COSMIC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q01196	RUNX1	P27361	MAPK3	T219	P216L	216	Missense	distal	-3	no	13.849	13.765	EPSD	COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q01196	RUNX1	P27361	MAPK3	T219	A217V	217	Missense	proximal	-2	no	13.849	14.546	EPSD	COSMIC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q01196	RUNX1	P27361	MAPK3	T219	R223P	223	Missense	distal	4	no	13.849	13.947	EPSD	COSMIC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q01196	RUNX1	P27361	MAPK3	T219	P218L	218	Missense	proximal	-1	no	13.849	13.755	EPSD	COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q01196	RUNX1	P27361	MAPK3	T219	R223H	223	Missense	distal	4	no	13.849	13.855	EPSD	COSMIC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q01196	RUNX1	P27361	MAPK3	T219	P222S	222	Missense	distal	3	no	13.849	13.845	EPSD	COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q01196	RUNX1	P27361	MAPK3	S225	L226F	226	Missense	proximal	1	no	7.415	10.239	EPSD	COSMIC	9.358	Gain
CMGC_MAPK_ERK1_MAPK3_ST	Q01196	RUNX1	P27361	MAPK3	S249	T243I	243	Missense	distal	-6	no	15.212	14.982	EPSD	COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q01196	RUNX1	P27361	MAPK3	S249	P250L	250	Missense	proximal	1	no	15.212	6.174	EPSD	COSMIC	9.358	Loss
CMGC_MAPK_ERK1_MAPK3_ST	Q01196	RUNX1	P27361	MAPK3	S249	P251L	251	Missense	proximal	2	no	15.212	15.191	EPSD	COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q01196	RUNX1	P27361	MAPK3	S249	T243K	243	Missense	distal	-6	no	15.212	15.222	EPSD	COSMIC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q01196	RUNX1	P27361	MAPK3	S253	P250L	250	Missense	distal	-3	no	11.376	11.292	EPSD	COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q01196	RUNX1	P27361	MAPK3	S253	P251L	251	Missense	proximal	-2	no	11.376	9.992	EPSD	COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q01196	RUNX1	P27361	MAPK3	S253	Y260F	260	Missense	distal	7	no	11.376	11.612	EPSD	COSMIC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q01196	RUNX1	P27361	MAPK3	S253	Y258C	258	Missense	distal	5	no	11.376	11.069	EPSD	COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q01196	RUNX1	P27361	MAPK3	S266	S268F	268	Missense	proximal	2	no	14.622	14.572	EPSD	COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q01196	RUNX1	P27361	MAPK3	S266	P267S	267	Missense	proximal	1	no	14.622	5.569	EPSD	COSMIC	9.358	Loss
CMGC_MAPK_ERK1_MAPK3_ST	Q01196	RUNX1	P27361	MAPK3	S266	T273M	273	Missense	distal	7	no	14.622	14.954	EPSD	COSMIC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q01196	RUNX1	P27361	MAPK3	S266	G262R	262	Missense	distal	-4	no	14.622	14.584	EPSD	COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q01196	RUNX1	P27361	MAPK3	S266	P271Q	271	Missense	distal	5	no	14.622	14.520	EPSD	COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q01196	RUNX1	P27361	MAPK3	S266	Y260F	260	Missense	distal	-6	no	14.622	14.408	EPSD	COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q01196	RUNX1	P27361	MAPK3	S266	P271S	271	Missense	distal	5	no	14.622	14.665	EPSD	COSMIC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q01196	RUNX1	P27361	MAPK3	S266	A265S	265	Missense	proximal	-1	no	14.622	14.756	EPSD	COSMIC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q01196	RUNX1	P27361	MAPK3	S266	L261P	261	Missense	distal	-5	no	14.622	14.677	EPSD	COSMIC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q01196	RUNX1	P27361	MAPK3	S266	A272G	272	Missense	distal	6	no	14.622	14.915	EPSD	COSMIC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q01196	RUNX1	P27361	MAPK3	T273	P277L	277	Missense	distal	4	no	16.566	16.411	EPSD	COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q01196	RUNX1	P27361	MAPK3	T273	S268F	268	Missense	distal	-5	no	16.566	16.432	EPSD	COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q01196	RUNX1	P27361	MAPK3	T273	P267S	267	Missense	distal	-6	no	16.566	16.650	EPSD	COSMIC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q01196	RUNX1	P27361	MAPK3	T273	S276L	276	Missense	distal	3	no	16.566	16.534	EPSD	COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q01196	RUNX1	P27361	MAPK3	T273	T273M	273	Missense	central	0	yes	16.566	0.000	EPSD	COSMIC	9.358	Loss
CMGC_MAPK_ERK1_MAPK3_ST	Q01196	RUNX1	P27361	MAPK3	T273	P271Q	271	Missense	proximal	-2	no	16.566	14.802	EPSD	COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q01196	RUNX1	P27361	MAPK3	T273	P271S	271	Missense	proximal	-2	no	16.566	15.490	EPSD	COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q01196	RUNX1	P27361	MAPK3	T273	R279C	279	Missense	distal	6	no	16.566	15.940	EPSD	COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q01196	RUNX1	P27361	MAPK3	T273	A272G	272	Missense	proximal	-1	no	16.566	16.634	EPSD	COSMIC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q01196	RUNX1	P27361	MAPK3	T273	R279P	279	Missense	distal	6	no	16.566	16.678	EPSD	COSMIC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q01196	RUNX1	P27361	MAPK3	S276	P277L	277	Missense	proximal	1	no	17.718	8.680	PhosphoSitePlus;EPSD	COSMIC	9.358	Loss
CMGC_MAPK_ERK1_MAPK3_ST	Q01196	RUNX1	P27361	MAPK3	S276	S276L	276	Missense	central	0	yes	17.718	0.000	PhosphoSitePlus;EPSD	COSMIC	9.358	Loss
CMGC_MAPK_ERK1_MAPK3_ST	Q01196	RUNX1	P27361	MAPK3	S276	T273M	273	Missense	distal	-3	no	17.718	17.621	PhosphoSitePlus;EPSD	COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q01196	RUNX1	P27361	MAPK3	S276	G282S	282	Missense	distal	6	no	17.718	17.950	PhosphoSitePlus;EPSD	COSMIC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q01196	RUNX1	P27361	MAPK3	S276	P271Q	271	Missense	distal	-5	no	17.718	17.670	PhosphoSitePlus;EPSD	COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q01196	RUNX1	P27361	MAPK3	S276	P271S	271	Missense	distal	-5	no	17.718	17.723	PhosphoSitePlus;EPSD	COSMIC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q01196	RUNX1	P27361	MAPK3	S276	R279C	279	Missense	distal	3	no	17.718	17.654	PhosphoSitePlus;EPSD	COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q01196	RUNX1	P27361	MAPK3	S276	A272G	272	Missense	distal	-4	no	17.718	17.811	PhosphoSitePlus;EPSD	COSMIC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q01196	RUNX1	P27361	MAPK3	S276	R279P	279	Missense	distal	3	no	17.718	17.744	PhosphoSitePlus;EPSD	COSMIC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q01196	RUNX1	P27361	MAPK3	S329	F326S	326	Missense	distal	-3	no	16.748	16.890	EPSD	COSMIC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q01196	RUNX1	P27361	MAPK3	S329	P323S	323	Missense	distal	-6	no	16.748	16.833	EPSD	COSMIC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q01196	RUNX1	P27361	MAPK3	S329	P332L	332	Missense	distal	3	no	16.748	16.712	EPSD	COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q01196	RUNX1	P27361	MAPK3	S329	S335L	335	Missense	distal	6	no	16.748	16.392	EPSD	COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q01196	RUNX1	P27361	MAPK3	T331	F326S	326	Missense	distal	-5	no	14.765	14.900	EPSD	COSMIC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q01196	RUNX1	P27361	MAPK3	T331	G338V	338	Missense	distal	7	no	14.765	14.944	EPSD	COSMIC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q01196	RUNX1	P27361	MAPK3	T331	P332L	332	Missense	proximal	1	no	14.765	5.727	EPSD	COSMIC	9.358	Loss
CMGC_MAPK_ERK1_MAPK3_ST	Q01196	RUNX1	P27361	MAPK3	T331	S335L	335	Missense	distal	4	no	14.765	14.562	EPSD	COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q01196	RUNX1	P27361	MAPK3	S373	G367D	367	Missense	distal	-6	no	15.549	15.550	EPSD	COSMIC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q01196	RUNX1	P27361	MAPK3	S373	S373L	373	Missense	central	0	yes	15.549	0.000	EPSD	COSMIC	9.358	Loss
CMGC_MAPK_ERK1_MAPK3_ST	Q01196	RUNX1	P27361	MAPK3	S373	Q370R	370	Missense	distal	-3	no	15.549	15.556	EPSD	COSMIC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q01196	RUNX1	P27361	MAPK3	S373	P368M	368	Missense	distal	-5	no	15.549	15.435	EPSD	COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q01196	RUNX1	P27361	MAPK3	S373	Y380C	380	Missense	distal	7	no	15.549	15.906	EPSD	COSMIC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q01196	RUNX1	P27361	MAPK3	S373	S375F	375	Missense	proximal	2	no	15.549	15.498	EPSD	COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q01196	RUNX1	P27361	MAPK3	S373	G366A	366	Missense	distal	-7	no	15.549	15.661	EPSD	COSMIC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q01196	RUNX1	P27361	MAPK3	S373	F369I	369	Missense	distal	-4	no	15.549	15.578	EPSD	COSMIC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q01196	RUNX1	P27361	MAPK3	S373	P368L	368	Missense	distal	-5	no	15.549	15.494	EPSD	COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q01196	RUNX1	P27361	MAPK3	S375	S373L	373	Missense	proximal	-2	no	9.448	9.139	EPSD	COSMIC	9.358	Loss
CMGC_MAPK_ERK1_MAPK3_ST	Q01196	RUNX1	P27361	MAPK3	S375	Q370R	370	Missense	distal	-5	no	9.448	9.455	EPSD	COSMIC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q01196	RUNX1	P27361	MAPK3	S375	P368M	368	Missense	distal	-7	no	9.448	9.615	EPSD	COSMIC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q01196	RUNX1	P27361	MAPK3	S375	Y380C	380	Missense	distal	5	no	9.448	9.140	EPSD	COSMIC	9.358	Loss
CMGC_MAPK_ERK1_MAPK3_ST	Q01196	RUNX1	P27361	MAPK3	S375	G381V	381	Missense	distal	6	no	9.448	9.242	EPSD	COSMIC	9.358	Loss
CMGC_MAPK_ERK1_MAPK3_ST	Q01196	RUNX1	P27361	MAPK3	S375	S375F	375	Missense	central	0	yes	9.448	0.000	EPSD	COSMIC	9.358	Loss
CMGC_MAPK_ERK1_MAPK3_ST	Q01196	RUNX1	P27361	MAPK3	S375	G381C	381	Missense	distal	6	no	9.448	8.813	EPSD	COSMIC	9.358	Loss
CMGC_MAPK_ERK1_MAPK3_ST	Q01196	RUNX1	P27361	MAPK3	S375	F369I	369	Missense	distal	-6	no	9.448	9.516	EPSD	COSMIC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q01196	RUNX1	P27361	MAPK3	S375	P368L	368	Missense	distal	-7	no	9.448	9.555	EPSD	COSMIC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q01196	RUNX1	P27361	MAPK3	S375	G381R	381	Missense	distal	6	no	9.448	9.438	EPSD	COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q01196	RUNX1	P27361	MAPK3	S386	A384T	384	Missense	proximal	-2	no	8.212	9.577	EPSD	COSMIC	9.358	Gain
CMGC_MAPK_ERK1_MAPK3_ST	Q01196	RUNX1	P27361	MAPK3	S397	G393A	393	Missense	distal	-4	no	15.994	15.901	EPSD	COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q01196	RUNX1	P27361	MAPK3	S397	E395K	395	Missense	proximal	-2	no	15.994	15.300	EPSD	COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q01196	RUNX1	P27361	MAPK3	S397	V392G	392	Missense	distal	-5	no	15.994	16.026	EPSD	COSMIC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q01196	RUNX1	P27361	MAPK3	S397	S397L	397	Missense	central	0	yes	15.994	0.000	EPSD	COSMIC	9.358	Loss
CMGC_MAPK_ERK1_MAPK3_ST	Q01196	RUNX1	P27361	MAPK3	S397	P398Q	398	Missense	proximal	1	no	15.994	8.050	EPSD	COSMIC	9.358	Loss
CMGC_MAPK_ERK1_MAPK3_ST	Q01196	RUNX1	P27361	MAPK3	S397	P398L	398	Missense	proximal	1	no	15.994	6.956	EPSD	COSMIC	9.358	Loss
CMGC_MAPK_ERK1_MAPK3_ST	Q01196	RUNX1	P27361	MAPK3	S397	R396H	396	Missense	proximal	-1	no	15.994	15.996	EPSD	COSMIC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q01196	RUNX1	P27361	MAPK3	S397	G394S	394	Missense	distal	-3	no	15.994	16.026	EPSD	COSMIC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q01196	RUNX1	P27361	MAPK3	S397	G393D	393	Missense	distal	-4	no	15.994	15.997	EPSD	COSMIC;CCLE	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q01196	RUNX1	P27361	MAPK3	S397	R400H	400	Missense	distal	3	no	15.994	16.002	EPSD	COSMIC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q01196	RUNX1	P27361	MAPK3	S397	P399T	399	Missense	proximal	2	no	15.994	15.984	EPSD	COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q01196	RUNX1	P27361	MAPK3	S397	R396P	396	Missense	proximal	-1	no	15.994	16.041	EPSD	COSMIC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q01196	RUNX1	P27361	MAPK3	S397	S390F	390	Missense	distal	-7	no	15.994	16.213	EPSD	COSMIC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q01196	RUNX1	P27361	MAPK3	S397	S397P	397	Missense	central	0	yes	15.994	0.000	EPSD	COSMIC	9.358	Loss
CMGC_MAPK_ERK1_MAPK3_ST	Q01196	RUNX1	P27361	MAPK3	S397	R396C	396	Missense	proximal	-1	no	15.994	15.809	EPSD	COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q01196	RUNX1	P27361	MAPK3	S397	S397A	397	Missense	central	0	yes	15.994	0.000	EPSD	COSMIC	9.358	Loss
CMGC_MAPK_ERK1_MAPK3_ST	Q01196	RUNX1	P27361	MAPK3	S431	E429D	429	Missense	proximal	-2	no	10.464	10.503	EPSD	COSMIC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q01196	RUNX1	P27361	MAPK3	S431	S433N	433	Missense	proximal	2	no	10.464	10.447	EPSD	COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q01196	RUNX1	P27361	MAPK3	S431	P436C	436	Missense	distal	5	no	10.464	9.984	EPSD	COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q01196	RUNX1	P27361	MAPK3	S431	V425M	425	Missense	distal	-6	no	10.464	10.372	EPSD	COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q01196	RUNX1	P27361	MAPK3	S431	E429K	429	Missense	proximal	-2	no	10.464	9.770	EPSD	COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q01196	RUNX1	P27361	MAPK3	S431	S431G	431	Missense	central	0	yes	10.464	0.000	EPSD	COSMIC	9.358	Loss
CMGC_MAPK_ERK1_MAPK3_ST	Q01196	RUNX1	P27361	MAPK3	S431	V426M	426	Missense	distal	-5	no	10.464	10.422	EPSD	COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q01196	RUNX1	P27361	MAPK3	S431	V426E	426	Missense	distal	-5	no	10.464	10.505	EPSD	COSMIC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q01196	RUNX1	P27361	MAPK3	S435	E429D	429	Missense	distal	-6	no	19.908	19.864	EPSD	COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q01196	RUNX1	P27361	MAPK3	S435	A440V	440	Missense	distal	5	no	19.908	19.897	EPSD	COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q01196	RUNX1	P27361	MAPK3	S435	S433N	433	Missense	proximal	-2	no	19.908	18.964	EPSD	COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q01196	RUNX1	P27361	MAPK3	S435	P436C	436	Missense	proximal	1	no	19.908	4.600	EPSD	COSMIC	9.358	Loss
CMGC_MAPK_ERK1_MAPK3_ST	Q01196	RUNX1	P27361	MAPK3	S435	S442F	442	Missense	distal	7	no	19.908	20.399	EPSD	COSMIC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q01196	RUNX1	P27361	MAPK3	S435	E429K	429	Missense	distal	-6	no	19.908	19.766	EPSD	COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q01196	RUNX1	P27361	MAPK3	S435	S431G	431	Missense	distal	-4	no	19.908	19.870	EPSD	COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q01196	RUNX1	P27361	MAPK3	S435	M439L	439	Missense	distal	4	no	19.908	20.083	EPSD	COSMIC;CCLE	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q01196	RUNX1	P27361	MAPK3	S435	M439T	439	Missense	distal	4	no	19.908	20.173	EPSD	COSMIC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q01196	RUNX1	P27361	MAPK3	S442	A440V	440	Missense	proximal	-2	no	8.749	9.445	EPSD	COSMIC	9.358	Gain
CMGC_MAPK_ERK1_MAPK3_ST	Q01860	POU5F1	P27361	MAPK3	S12	A10S	10	Missense	proximal	-2	no	14.085	15.359	EPSD	COSMIC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q01860	POU5F1	P27361	MAPK3	T118	V122M	122	Missense	distal	4	no	16.550	16.395	EPSD	COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q01860	POU5F1	P27361	MAPK3	T118	A121V	121	Missense	distal	3	no	16.550	16.556	EPSD	COSMIC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P49841	GSK3B	P27361	MAPK3	S21	A22T	22	Missense	proximal	1	no	9.036	9.399	EPSD	COSMIC	9.358	Gain
CMGC_MAPK_ERK1_MAPK3_ST	P49841	GSK3B	P27361	MAPK3	T43	G47C	47	Missense	distal	4	no	15.457	15.114	EPSD;PhosphoSitePlus	COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P49841	GSK3B	P27361	MAPK3	T43	V41G	41	Missense	proximal	-2	no	15.457	14.995	EPSD;PhosphoSitePlus	COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P49841	GSK3B	P27361	MAPK3	T43	V37G	37	Missense	distal	-6	no	15.457	15.724	EPSD;PhosphoSitePlus	COSMIC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P49841	GSK3B	P27361	MAPK3	S66	Y71H	71	Missense	distal	5	no	9.307	9.415	EPSD	COSMIC	9.358	Gain
CMGC_MAPK_ERK1_MAPK3_ST	P49841	GSK3B	P27361	MAPK3	T275	R278M	278	Missense	distal	3	no	15.173	15.133	EPSD	COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P49841	GSK3B	P27361	MAPK3	T324	R319C	319	Missense	distal	-5	no	14.724	14.608	EPSD	COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P49841	GSK3B	P27361	MAPK3	T324	R319Q	319	Missense	distal	-5	no	14.724	14.717	EPSD	COSMIC;GDSC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P49841	GSK3B	P27361	MAPK3	T390	Q385P	385	Missense	distal	-5	no	13.079	13.127	PhosphoSitePlus;EPSD	COSMIC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P49841	GSK3B	P27361	MAPK3	T390	P391L	391	Missense	proximal	1	no	13.079	4.041	PhosphoSitePlus;EPSD	COSMIC	9.358	Loss
CMGC_MAPK_ERK1_MAPK3_ST	P49841	GSK3B	P27361	MAPK3	T390	A397V	397	Missense	distal	7	no	13.079	13.051	PhosphoSitePlus;EPSD	COSMIC;CCLE	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q16584	MAP3K11	P27361	MAPK3	S15	S19N	19	Missense	distal	4	no	11.096	10.950	EPSD	COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q16584	MAP3K11	P27361	MAPK3	S35	R31W	31	Missense	distal	-4	no	17.686	17.478	EPSD	COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q16584	MAP3K11	P27361	MAPK3	S507	T503A	503	Missense	distal	-4	no	15.795	15.721	EPSD	COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q16584	MAP3K11	P27361	MAPK3	S507	H500R	500	Missense	distal	-7	no	15.795	15.806	EPSD	COSMIC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q16584	MAP3K11	P27361	MAPK3	S507	R501C	501	Missense	distal	-6	no	15.795	15.396	EPSD	COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q16584	MAP3K11	P27361	MAPK3	S524	G520W	520	Missense	distal	-4	no	15.473	15.227	EPSD	COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q16584	MAP3K11	P27361	MAPK3	S524	P521S	521	Missense	distal	-3	no	15.473	15.464	EPSD	COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q16584	MAP3K11	P27361	MAPK3	S570	W566C	566	Missense	distal	-4	no	17.779	17.825	EPSD	COSMIC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q16584	MAP3K11	P27361	MAPK3	S570	W564L	564	Missense	distal	-6	no	17.779	18.130	EPSD	COSMIC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q16584	MAP3K11	P27361	MAPK3	S674	T680M	680	Missense	distal	6	no	16.454	15.960	EPSD	COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q16584	MAP3K11	P27361	MAPK3	S674	G672R	672	Missense	proximal	-2	no	16.454	17.170	EPSD	COSMIC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q16584	MAP3K11	P27361	MAPK3	S674	R671H	671	Missense	distal	-3	no	16.454	16.461	EPSD	COSMIC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q16584	MAP3K11	P27361	MAPK3	S674	P679L	679	Missense	distal	5	no	16.454	16.226	EPSD	COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q16584	MAP3K11	P27361	MAPK3	S674	P667S	667	Missense	distal	-7	no	16.454	16.417	EPSD	COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q16584	MAP3K11	P27361	MAPK3	T677	T680M	680	Missense	distal	3	no	17.924	17.876	EPSD	COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q16584	MAP3K11	P27361	MAPK3	T677	G672R	672	Missense	distal	-5	no	17.924	17.922	EPSD	COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q16584	MAP3K11	P27361	MAPK3	T677	R671H	671	Missense	distal	-6	no	17.924	17.920	EPSD	COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q16584	MAP3K11	P27361	MAPK3	T677	P683S	683	Missense	distal	6	no	17.924	18.054	EPSD	COSMIC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q16584	MAP3K11	P27361	MAPK3	T677	P679L	679	Missense	proximal	2	no	17.924	17.903	EPSD	COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q16584	MAP3K11	P27361	MAPK3	T677	P683L	683	Missense	distal	6	no	17.924	17.698	EPSD	COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q16584	MAP3K11	P27361	MAPK3	T680	T680M	680	Missense	central	0	yes	15.975	0.000	EPSD	COSMIC	9.358	Loss
CMGC_MAPK_ERK1_MAPK3_ST	Q16584	MAP3K11	P27361	MAPK3	T680	P683S	683	Missense	distal	3	no	15.975	15.970	EPSD	COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q16584	MAP3K11	P27361	MAPK3	T680	P679L	679	Missense	proximal	-1	no	15.975	15.880	EPSD	COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q16584	MAP3K11	P27361	MAPK3	T680	P683L	683	Missense	distal	3	no	15.975	15.938	EPSD	COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q16584	MAP3K11	P27361	MAPK3	T682	T680M	680	Missense	proximal	-2	no	15.983	14.215	EPSD	COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q16584	MAP3K11	P27361	MAPK3	T682	P683S	683	Missense	proximal	1	no	15.983	6.930	EPSD	COSMIC	9.358	Loss
CMGC_MAPK_ERK1_MAPK3_ST	Q16584	MAP3K11	P27361	MAPK3	T682	P679L	679	Missense	distal	-3	no	15.983	15.899	EPSD	COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q16584	MAP3K11	P27361	MAPK3	T682	P683L	683	Missense	proximal	1	no	15.983	6.945	EPSD	COSMIC	9.358	Loss
CMGC_MAPK_ERK1_MAPK3_ST	Q16584	MAP3K11	P27361	MAPK3	S693	P691H	691	Missense	proximal	-2	no	17.772	16.544	EPSD	COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q16584	MAP3K11	P27361	MAPK3	S693	I696F	696	Missense	distal	3	no	17.772	17.758	EPSD	COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q16584	MAP3K11	P27361	MAPK3	T702	T702M	702	Missense	central	0	yes	14.155	0.000	EPSD	COSMIC	9.358	Loss
CMGC_MAPK_ERK1_MAPK3_ST	Q16584	MAP3K11	P27361	MAPK3	T702	I696F	696	Missense	distal	-6	no	14.155	14.086	EPSD	COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q16584	MAP3K11	P27361	MAPK3	T702	D704A	704	Missense	proximal	2	no	14.155	14.128	EPSD	COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q16584	MAP3K11	P27361	MAPK3	S705	T702M	702	Missense	distal	-3	no	17.626	17.529	PhosphoSitePlus;EPSD	COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q16584	MAP3K11	P27361	MAPK3	S705	D704A	704	Missense	proximal	-1	no	17.626	17.539	PhosphoSitePlus;EPSD	COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q16584	MAP3K11	P27361	MAPK3	T708	T702M	702	Missense	distal	-6	no	15.274	15.021	EPSD	COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q16584	MAP3K11	P27361	MAPK3	T708	D704A	704	Missense	distal	-4	no	15.274	15.177	EPSD	COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q16584	MAP3K11	P27361	MAPK3	S727	R730H	730	Missense	distal	3	no	16.214	16.222	EPSD	COSMIC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q16584	MAP3K11	P27361	MAPK3	S727	Q722L	722	Missense	distal	-5	no	16.214	16.208	EPSD	COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q16584	MAP3K11	P27361	MAPK3	S740	R735C	735	Missense	distal	-5	no	17.364	17.248	EPSD	COSMIC;GDSC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q16584	MAP3K11	P27361	MAPK3	S740	R735S	735	Missense	distal	-5	no	17.364	17.410	EPSD	COSMIC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q16584	MAP3K11	P27361	MAPK3	T752	P750S	750	Missense	proximal	-2	no	18.143	17.067	EPSD	COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q16584	MAP3K11	P27361	MAPK3	T755	G762V	762	Missense	distal	7	no	15.926	16.105	EPSD	COSMIC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q16584	MAP3K11	P27361	MAPK3	T755	P750S	750	Missense	distal	-5	no	15.926	15.931	EPSD	COSMIC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q16584	MAP3K11	P27361	MAPK3	S758	G762V	762	Missense	distal	4	no	16.235	16.173	EPSD;PhosphoSitePlus	COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q16584	MAP3K11	P27361	MAPK3	S770	L772F	772	Missense	proximal	2	no	14.890	14.863	EPSD	COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q16584	MAP3K11	P27361	MAPK3	S770	R773H	773	Missense	distal	3	no	14.890	14.898	EPSD	COSMIC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q16584	MAP3K11	P27361	MAPK3	S780	P786S	786	Missense	distal	6	no	11.080	11.209	EPSD	COSMIC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q16584	MAP3K11	P27361	MAPK3	S780	R773H	773	Missense	distal	-7	no	11.080	11.069	EPSD	COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q16584	MAP3K11	P27361	MAPK3	S789	P786S	786	Missense	distal	-3	no	16.353	16.344	EPSD	COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q16584	MAP3K11	P27361	MAPK3	S793	P786S	786	Missense	distal	-7	no	17.525	17.487	EPSD	COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q16584	MAP3K11	P27361	MAPK3	S793	R799C	799	Missense	distal	6	no	17.525	16.899	EPSD	COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q16584	MAP3K11	P27361	MAPK3	S815	D808E	808	Missense	distal	-7	no	11.816	11.805	EPSD	COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q16584	MAP3K11	P27361	MAPK3	S815	D810H	810	Missense	distal	-5	no	11.816	11.814	EPSD	COSMIC;GDSC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q96FF9	CDCA5	P27361	MAPK3	S15	G16R	16	Missense	proximal	1	no	8.350	10.388	EPSD	COSMIC	9.358	Gain
CMGC_MAPK_ERK1_MAPK3_ST	Q96FF9	CDCA5	P27361	MAPK3	S21	R18K	18	Missense	distal	-3	no	17.568	17.555	EPSD	COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q96FF9	CDCA5	P27361	MAPK3	S21	G16R	16	Missense	distal	-5	no	17.568	17.566	EPSD	COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q96FF9	CDCA5	P27361	MAPK3	T48	T48I	48	Missense	central	0	yes	17.066	0.000	EPSD	COSMIC	9.358	Loss
CMGC_MAPK_ERK1_MAPK3_ST	Q96FF9	CDCA5	P27361	MAPK3	S75	V68I	68	Missense	distal	-7	no	16.138	16.180	EPSD	COSMIC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q96FF9	CDCA5	P27361	MAPK3	S75	R81S	81	Missense	distal	6	no	16.138	16.379	EPSD	COSMIC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q96FF9	CDCA5	P27361	MAPK3	S79	R81S	81	Missense	proximal	2	no	14.812	14.825	EPSD;PhosphoSitePlus	COSMIC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q96FF9	CDCA5	P27361	MAPK3	S83	R81S	81	Missense	proximal	-2	no	10.115	10.439	EPSD	COSMIC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q96FF9	CDCA5	P27361	MAPK3	T111	P116F	116	Missense	distal	5	no	16.827	16.445	EPSD	COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q96FF9	CDCA5	P27361	MAPK3	S114	P116F	116	Missense	proximal	2	no	9.766	9.718	EPSD	COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q96FF9	CDCA5	P27361	MAPK3	T115	P116F	116	Missense	proximal	1	no	15.340	9.126	EPSD	COSMIC	9.358	Loss
CMGC_MAPK_ERK1_MAPK3_ST	Q96FF9	CDCA5	P27361	MAPK3	T159	G161S	161	Missense	proximal	2	no	14.467	14.484	EPSD	COSMIC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q96FF9	CDCA5	P27361	MAPK3	T159	S164F	164	Missense	distal	5	no	14.467	14.042	EPSD	COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q96FF9	CDCA5	P27361	MAPK3	S181	S181L	181	Missense	central	0	yes	13.270	0.000	EPSD	COSMIC	9.358	Loss
CMGC_MAPK_ERK1_MAPK3_ST	Q96FF9	CDCA5	P27361	MAPK3	S209	L205F	205	Missense	distal	-4	no	14.429	14.380	PhosphoSitePlus;EPSD	COSMIC;GDSC;CCLE	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P23396	RPS3	P27361	MAPK3	T42	P43S	43	Missense	proximal	1	no	15.833	6.779	PhosphoSitePlus	COSMIC	9.358	Loss
CMGC_MAPK_ERK1_MAPK3_ST	P17861	XBP1	P27361	MAPK3	T14	D12V	12	Missense	proximal	-2	no	14.755	14.708	EPSD	COSMIC;GDSC;CCLE	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P17861	XBP1	P27361	MAPK3	S47	S47R	47	Missense	central	0	yes	15.607	0.000	EPSD	COSMIC	9.358	Loss
CMGC_MAPK_ERK1_MAPK3_ST	P17861	XBP1	P27361	MAPK3	S47	A51V	51	Missense	distal	4	no	15.607	15.715	EPSD	COSMIC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P17861	XBP1	P27361	MAPK3	S47	E49K	49	Missense	proximal	2	no	15.607	15.600	EPSD	COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P17861	XBP1	P27361	MAPK3	S68	T65M	65	Missense	distal	-3	no	17.359	17.262	PhosphoSitePlus;EPSD	COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P17861	XBP1	P27361	MAPK3	S181	Q179R	179	Missense	proximal	-2	no	16.372	16.736	EPSD;PhosphoSitePlus	COSMIC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P17861	XBP1	P27361	MAPK3	S181	S187C	187	Missense	distal	6	no	16.372	15.505	EPSD;PhosphoSitePlus	COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q8IZP0	ABI1	P27361	MAPK3	S22	N25S	25	Missense	distal	3	no	10.338	10.359	EPSD	COSMIC;CCLE	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q8IZP0	ABI1	P27361	MAPK3	S183	G190E	190	Missense	distal	7	no	18.665	18.630	EPSD;PhosphoSitePlus	COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q8IZP0	ABI1	P27361	MAPK3	S183	G188R	188	Missense	distal	5	no	18.665	18.586	EPSD;PhosphoSitePlus	COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q8IZP0	ABI1	P27361	MAPK3	T196	G193R	193	Missense	distal	-3	no	14.732	14.727	EPSD	COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q8IZP0	ABI1	P27361	MAPK3	T196	G190E	190	Missense	distal	-6	no	14.732	14.778	EPSD	COSMIC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q8IZP0	ABI1	P27361	MAPK3	T196	N195S	195	Missense	proximal	-1	no	14.732	14.781	EPSD	COSMIC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q8IZP0	ABI1	P27361	MAPK3	S216	T215N	215	Missense	proximal	-1	no	14.903	14.884	EPSD;PhosphoSitePlus	COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q8IZP0	ABI1	P27361	MAPK3	S216	P217L	217	Missense	proximal	1	no	14.903	5.865	EPSD;PhosphoSitePlus	COSMIC	9.358	Loss
CMGC_MAPK_ERK1_MAPK3_ST	Q8IZP0	ABI1	P27361	MAPK3	S225	H224Y	224	Missense	proximal	-1	no	15.792	15.754	EPSD;PhosphoSitePlus	COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q8IZP0	ABI1	P27361	MAPK3	T238	S240I	240	Missense	proximal	2	no	10.382	10.347	EPSD	COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q8IZP0	ABI1	P27361	MAPK3	T238	S243G	243	Missense	distal	5	no	10.382	10.318	EPSD	COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q8IZP0	ABI1	P27361	MAPK3	T265	P266H	266	Missense	proximal	1	no	15.364	7.608	EPSD;PhosphoSitePlus	COSMIC	9.358	Loss
CMGC_MAPK_ERK1_MAPK3_ST	Q8IZP0	ABI1	P27361	MAPK3	T265	P268T	268	Missense	distal	3	no	15.364	15.345	EPSD;PhosphoSitePlus	COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q8IZP0	ABI1	P27361	MAPK3	S267	P266H	266	Missense	proximal	-1	no	15.644	15.599	EPSD;PhosphoSitePlus	COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q8IZP0	ABI1	P27361	MAPK3	S267	P268T	268	Missense	proximal	1	no	15.644	6.767	EPSD;PhosphoSitePlus	COSMIC	9.358	Loss
CMGC_MAPK_ERK1_MAPK3_ST	Q8IZP0	ABI1	P27361	MAPK3	T325	S326F	326	Missense	proximal	1	no	7.478	10.317	EPSD	COSMIC	9.358	Gain
CMGC_MAPK_ERK1_MAPK3_ST	Q8IZP0	ABI1	P27361	MAPK3	T336	P337T	337	Missense	proximal	1	no	15.296	6.418	EPSD	COSMIC	9.358	Loss
CMGC_MAPK_ERK1_MAPK3_ST	Q8IZP0	ABI1	P27361	MAPK3	T336	S338C	338	Missense	proximal	2	no	15.296	15.234	EPSD	COSMIC;GDSC;CCLE	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q8IZP0	ABI1	P27361	MAPK3	T336	T336A	336	Missense	central	0	yes	15.296	0.000	EPSD	COSMIC	9.358	Loss
CMGC_MAPK_ERK1_MAPK3_ST	Q8IZP0	ABI1	P27361	MAPK3	S392	P399S	399	Missense	distal	7	no	14.393	14.315	EPSD;PhosphoSitePlus	COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q8IZP0	ABI1	P27361	MAPK3	S392	A390T	390	Missense	proximal	-2	no	14.393	15.758	EPSD;PhosphoSitePlus	COSMIC;GDSC;CCLE	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q8IZP0	ABI1	P27361	MAPK3	S392	P399T	399	Missense	distal	7	no	14.393	14.434	EPSD;PhosphoSitePlus	COSMIC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q8IZP0	ABI1	P27361	MAPK3	T394	P400L	400	Missense	distal	6	no	14.735	14.508	EPSD;PhosphoSitePlus	COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q8IZP0	ABI1	P27361	MAPK3	T394	P399S	399	Missense	distal	5	no	14.735	14.778	EPSD;PhosphoSitePlus	COSMIC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q8IZP0	ABI1	P27361	MAPK3	T394	A390T	390	Missense	distal	-4	no	14.735	14.808	EPSD;PhosphoSitePlus	COSMIC;GDSC;CCLE	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q8IZP0	ABI1	P27361	MAPK3	T394	P399T	399	Missense	distal	5	no	14.735	14.642	EPSD;PhosphoSitePlus	COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q8IZP0	ABI1	P27361	MAPK3	S410	D403N	403	Missense	distal	-7	no	16.907	16.932	PhosphoSitePlus;EPSD	COSMIC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q8IZP0	ABI1	P27361	MAPK3	S410	P412H	412	Missense	proximal	2	no	16.907	16.894	PhosphoSitePlus;EPSD	COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q8IZP0	ABI1	P27361	MAPK3	S410	P416T	416	Missense	distal	6	no	16.907	16.882	PhosphoSitePlus;EPSD	COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q8IZP0	ABI1	P27361	MAPK3	S410	P414S	414	Missense	distal	4	no	16.907	16.956	PhosphoSitePlus;EPSD	COSMIC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q8IZP0	ABI1	P27361	MAPK3	S410	P412L	412	Missense	proximal	2	no	16.907	16.886	PhosphoSitePlus;EPSD	COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q8IZP0	ABI1	P27361	MAPK3	S410	P411S	411	Missense	proximal	1	no	16.907	7.854	PhosphoSitePlus;EPSD	COSMIC	9.358	Loss
CMGC_MAPK_ERK1_MAPK3_ST	Q8IZP0	ABI1	P27361	MAPK3	S410	P417T	417	Missense	distal	7	no	16.907	16.948	PhosphoSitePlus;EPSD	COSMIC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q8IZP0	ABI1	P27361	MAPK3	S410	P412T	412	Missense	proximal	2	no	16.907	16.898	PhosphoSitePlus;EPSD	COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q8IZP0	ABI1	P27361	MAPK3	S410	P413H	413	Missense	distal	3	no	16.907	16.888	PhosphoSitePlus;EPSD	COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q8IZP0	ABI1	P27361	MAPK3	S466	A471T	471	Missense	distal	5	no	9.532	9.652	EPSD	COSMIC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q8IZP0	ABI1	P27361	MAPK3	S466	D460N	460	Missense	distal	-6	no	9.532	9.470	EPSD	COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q8IZP0	ABI1	P27361	MAPK3	S466	G470V	470	Missense	distal	4	no	9.532	9.470	EPSD	COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q8IZP0	ABI1	P27361	MAPK3	S502	G497V	497	Missense	distal	-5	no	12.209	12.176	EPSD	COSMIC;CCLE	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P35658	NUP214	P27361	MAPK3	S30	V25M	25	Missense	distal	-5	no	15.068	15.025	EPSD	COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P35658	NUP214	P27361	MAPK3	S201	C199F	199	Missense	proximal	-2	no	15.156	16.296	EPSD	COSMIC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P35658	NUP214	P27361	MAPK3	S268	T267M	267	Missense	proximal	-1	no	15.272	15.147	EPSD	COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P35658	NUP214	P27361	MAPK3	S268	A274V	274	Missense	distal	6	no	15.272	15.359	EPSD	COSMIC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P35658	NUP214	P27361	MAPK3	S268	E266K	266	Missense	proximal	-2	no	15.272	14.578	EPSD	COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P35658	NUP214	P27361	MAPK3	S268	D262Y	262	Missense	distal	-6	no	15.272	15.079	EPSD	COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P35658	NUP214	P27361	MAPK3	T416	S412F	412	Missense	distal	-4	no	14.782	14.593	EPSD	COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P35658	NUP214	P27361	MAPK3	S430	G424A	424	Missense	distal	-6	no	18.796	18.542	EPSD	COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P35658	NUP214	P27361	MAPK3	S430	P435S	435	Missense	distal	5	no	18.796	18.839	EPSD	COSMIC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P35658	NUP214	P27361	MAPK3	S430	P431S	431	Missense	proximal	1	no	18.796	9.743	EPSD	COSMIC;GDSC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P35658	NUP214	P27361	MAPK3	S430	R426Q	426	Missense	distal	-4	no	18.796	18.807	EPSD	COSMIC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P35658	NUP214	P27361	MAPK3	S430	T437I	437	Missense	distal	7	no	18.796	19.076	EPSD	COSMIC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P35658	NUP214	P27361	MAPK3	S433	P435S	435	Missense	proximal	2	no	9.866	9.868	EPSD	COSMIC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P35658	NUP214	P27361	MAPK3	S433	P431S	431	Missense	proximal	-2	no	9.866	8.790	EPSD	COSMIC;GDSC	9.358	Loss
CMGC_MAPK_ERK1_MAPK3_ST	P35658	NUP214	P27361	MAPK3	S433	S440P	440	Missense	distal	7	no	9.866	9.944	EPSD	COSMIC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P35658	NUP214	P27361	MAPK3	S433	T437I	437	Missense	distal	4	no	9.866	9.638	EPSD	COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P35658	NUP214	P27361	MAPK3	T434	P435S	435	Missense	proximal	1	no	14.751	5.698	EPSD	COSMIC	9.358	Loss
CMGC_MAPK_ERK1_MAPK3_ST	P35658	NUP214	P27361	MAPK3	T434	P431S	431	Missense	distal	-3	no	14.751	14.743	EPSD	COSMIC;GDSC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P35658	NUP214	P27361	MAPK3	T434	S440P	440	Missense	distal	6	no	14.751	14.622	EPSD	COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P35658	NUP214	P27361	MAPK3	T434	T437I	437	Missense	distal	3	no	14.751	14.713	EPSD	COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P35658	NUP214	P27361	MAPK3	T437	P435S	435	Missense	proximal	-2	no	16.689	15.613	EPSD	COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P35658	NUP214	P27361	MAPK3	T437	P431S	431	Missense	distal	-6	no	16.689	16.773	EPSD	COSMIC;GDSC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P35658	NUP214	P27361	MAPK3	T437	S440P	440	Missense	distal	3	no	16.689	16.693	EPSD	COSMIC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P35658	NUP214	P27361	MAPK3	T437	T437I	437	Missense	central	0	yes	16.689	0.000	EPSD	COSMIC	9.358	Loss
CMGC_MAPK_ERK1_MAPK3_ST	P35658	NUP214	P27361	MAPK3	T439	S440P	440	Missense	proximal	1	no	7.609	16.663	EPSD	COSMIC	9.358	Gain
CMGC_MAPK_ERK1_MAPK3_ST	P35658	NUP214	P27361	MAPK3	S440	P435S	435	Missense	distal	-5	no	9.966	9.971	EPSD	COSMIC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P35658	NUP214	P27361	MAPK3	S440	S440P	440	Missense	central	0	yes	9.966	0.000	EPSD	COSMIC	9.358	Loss
CMGC_MAPK_ERK1_MAPK3_ST	P35658	NUP214	P27361	MAPK3	S440	T437I	437	Missense	distal	-3	no	9.966	9.885	EPSD	COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P35658	NUP214	P27361	MAPK3	S462	A465V	465	Missense	distal	3	no	16.511	16.517	EPSD	COSMIC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P35658	NUP214	P27361	MAPK3	S462	P455L	455	Missense	distal	-7	no	16.511	16.618	EPSD	COSMIC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P35658	NUP214	P27361	MAPK3	S462	A456T	456	Missense	distal	-6	no	16.511	16.659	EPSD	COSMIC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P35658	NUP214	P27361	MAPK3	S462	T469P	469	Missense	distal	7	no	16.511	16.470	EPSD	COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P35658	NUP214	P27361	MAPK3	S483	T480A	480	Missense	distal	-3	no	10.983	10.922	EPSD	COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P35658	NUP214	P27361	MAPK3	S483	A478T	478	Missense	distal	-5	no	10.983	11.066	EPSD	COSMIC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P35658	NUP214	P27361	MAPK3	S501	P499S	499	Missense	proximal	-2	no	12.628	11.552	EPSD	COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P35658	NUP214	P27361	MAPK3	T519	T519P	519	Missense	central	0	yes	11.920	0.000	EPSD	COSMIC	9.358	Loss
CMGC_MAPK_ERK1_MAPK3_ST	P35658	NUP214	P27361	MAPK3	T519	S518G	518	Missense	proximal	-1	no	11.920	11.854	EPSD	COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P35658	NUP214	P27361	MAPK3	T519	G516D	516	Missense	distal	-3	no	11.920	11.930	EPSD	COSMIC;CCLE	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P35658	NUP214	P27361	MAPK3	T519	P524L	524	Missense	distal	5	no	11.920	11.692	EPSD	COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P35658	NUP214	P27361	MAPK3	T533	L530Q	530	Missense	distal	-3	no	14.038	14.068	EPSD	COSMIC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P35658	NUP214	P27361	MAPK3	T533	K527E	527	Missense	distal	-6	no	14.038	14.180	EPSD	COSMIC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P35658	NUP214	P27361	MAPK3	T533	P534S	534	Missense	proximal	1	no	14.038	4.985	EPSD	COSMIC	9.358	Loss
CMGC_MAPK_ERK1_MAPK3_ST	P35658	NUP214	P27361	MAPK3	T533	S537A	537	Missense	distal	4	no	14.038	13.707	EPSD	COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P35658	NUP214	P27361	MAPK3	T533	A531T	531	Missense	proximal	-2	no	14.038	15.403	EPSD	COSMIC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P35658	NUP214	P27361	MAPK3	T533	A531V	531	Missense	proximal	-2	no	14.038	14.735	EPSD	COSMIC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P35658	NUP214	P27361	MAPK3	S537	L530Q	530	Missense	distal	-7	no	15.176	15.113	EPSD	COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P35658	NUP214	P27361	MAPK3	S537	P534S	534	Missense	distal	-3	no	15.176	15.168	EPSD	COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P35658	NUP214	P27361	MAPK3	S537	S537A	537	Missense	central	0	yes	15.176	0.000	EPSD	COSMIC	9.358	Loss
CMGC_MAPK_ERK1_MAPK3_ST	P35658	NUP214	P27361	MAPK3	S537	A531T	531	Missense	distal	-6	no	15.176	15.324	EPSD	COSMIC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P35658	NUP214	P27361	MAPK3	S537	A531V	531	Missense	distal	-6	no	15.176	15.163	EPSD	COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P35658	NUP214	P27361	MAPK3	T560	V562M	562	Missense	proximal	2	no	16.717	16.699	EPSD	COSMIC;GDSC;CCLE	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P35658	NUP214	P27361	MAPK3	T560	E558K	558	Missense	proximal	-2	no	16.717	16.023	EPSD	COSMIC;GDSC;CCLE	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P35658	NUP214	P27361	MAPK3	T560	L557F	557	Missense	distal	-3	no	16.717	16.651	EPSD	COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P35658	NUP214	P27361	MAPK3	T560	P561T	561	Missense	proximal	1	no	16.717	7.840	EPSD	COSMIC	9.358	Loss
CMGC_MAPK_ERK1_MAPK3_ST	P35658	NUP214	P27361	MAPK3	T560	P561L	561	Missense	proximal	1	no	16.717	7.679	EPSD	COSMIC	9.358	Loss
CMGC_MAPK_ERK1_MAPK3_ST	P35658	NUP214	P27361	MAPK3	T598	P599L	599	Missense	proximal	1	no	15.639	6.601	EPSD	COSMIC	9.358	Loss
CMGC_MAPK_ERK1_MAPK3_ST	P35658	NUP214	P27361	MAPK3	T598	P599S	599	Missense	proximal	1	no	15.639	6.586	EPSD	COSMIC	9.358	Loss
CMGC_MAPK_ERK1_MAPK3_ST	P35658	NUP214	P27361	MAPK3	T598	A595V	595	Missense	distal	-3	no	15.639	15.659	EPSD	COSMIC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P35658	NUP214	P27361	MAPK3	T598	A595T	595	Missense	distal	-3	no	15.639	15.701	EPSD	COSMIC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P35658	NUP214	P27361	MAPK3	T598	S605Y	605	Missense	distal	7	no	15.639	15.894	EPSD	COSMIC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P35658	NUP214	P27361	MAPK3	S610	S610L	610	Missense	central	0	yes	17.882	0.000	EPSD	COSMIC;GDSC;CCLE	9.358	Loss
CMGC_MAPK_ERK1_MAPK3_ST	P35658	NUP214	P27361	MAPK3	S610	A606V	606	Missense	distal	-4	no	17.882	17.862	EPSD	COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P35658	NUP214	P27361	MAPK3	S610	P608L	608	Missense	proximal	-2	no	17.882	16.498	EPSD	COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P35658	NUP214	P27361	MAPK3	S610	A606T	606	Missense	distal	-4	no	17.882	17.956	EPSD	COSMIC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P35658	NUP214	P27361	MAPK3	S610	S605Y	605	Missense	distal	-5	no	17.882	17.818	EPSD	COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P35658	NUP214	P27361	MAPK3	S625	G622V	622	Missense	distal	-3	no	9.540	9.501	EPSD	COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P35658	NUP214	P27361	MAPK3	S625	S625F	625	Missense	central	0	yes	9.540	0.000	EPSD	COSMIC	9.358	Loss
CMGC_MAPK_ERK1_MAPK3_ST	P35658	NUP214	P27361	MAPK3	S625	S631L	631	Missense	distal	6	no	9.540	9.184	EPSD	COSMIC	9.358	Loss
CMGC_MAPK_ERK1_MAPK3_ST	P35658	NUP214	P27361	MAPK3	S625	S631P	631	Missense	distal	6	no	9.540	9.411	EPSD	COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P35658	NUP214	P27361	MAPK3	S625	A619T	619	Missense	distal	-6	no	9.540	9.688	EPSD	COSMIC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P35658	NUP214	P27361	MAPK3	T628	G622V	622	Missense	distal	-6	no	14.879	14.611	EPSD	COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P35658	NUP214	P27361	MAPK3	T628	S625F	625	Missense	distal	-3	no	14.879	14.737	EPSD	COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P35658	NUP214	P27361	MAPK3	T628	S631L	631	Missense	distal	3	no	14.879	14.847	EPSD	COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P35658	NUP214	P27361	MAPK3	T628	S631P	631	Missense	distal	3	no	14.879	14.883	EPSD	COSMIC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P35658	NUP214	P27361	MAPK3	S635	S636F	636	Missense	proximal	1	no	7.401	10.240	EPSD	COSMIC	9.358	Gain
CMGC_MAPK_ERK1_MAPK3_ST	P35658	NUP214	P27361	MAPK3	S646	P647S	647	Missense	proximal	1	no	15.451	6.398	EPSD	COSMIC	9.358	Loss
CMGC_MAPK_ERK1_MAPK3_ST	P35658	NUP214	P27361	MAPK3	S646	L644S	644	Missense	proximal	-2	no	15.451	15.759	EPSD	COSMIC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P35658	NUP214	P27361	MAPK3	S646	S648L	648	Missense	proximal	2	no	15.451	15.428	EPSD	COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P35658	NUP214	P27361	MAPK3	S666	P672S	672	Missense	distal	6	no	17.714	17.844	EPSD	COSMIC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P35658	NUP214	P27361	MAPK3	S666	T670A	670	Missense	distal	4	no	17.714	17.496	EPSD	COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P35658	NUP214	P27361	MAPK3	S666	T670I	670	Missense	distal	4	no	17.714	17.486	EPSD	COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P35658	NUP214	P27361	MAPK3	T670	P672S	672	Missense	proximal	2	no	13.880	13.882	EPSD	COSMIC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P35658	NUP214	P27361	MAPK3	T670	T670A	670	Missense	central	0	yes	13.880	0.000	EPSD	COSMIC	9.358	Loss
CMGC_MAPK_ERK1_MAPK3_ST	P35658	NUP214	P27361	MAPK3	T670	A674T	674	Missense	distal	4	no	13.880	14.098	EPSD	COSMIC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P35658	NUP214	P27361	MAPK3	T670	T670I	670	Missense	central	0	yes	13.880	0.000	EPSD	COSMIC	9.358	Loss
CMGC_MAPK_ERK1_MAPK3_ST	P35658	NUP214	P27361	MAPK3	S678	P672S	672	Missense	distal	-6	no	16.323	16.408	EPSD	COSMIC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P35658	NUP214	P27361	MAPK3	S678	A674T	674	Missense	distal	-4	no	16.323	16.397	EPSD	COSMIC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P35658	NUP214	P27361	MAPK3	S678	K682N	682	Missense	distal	4	no	16.323	16.315	EPSD	COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P35658	NUP214	P27361	MAPK3	S807	P805H	805	Missense	proximal	-2	no	9.430	8.202	EPSD	COSMIC	9.358	Loss
CMGC_MAPK_ERK1_MAPK3_ST	P35658	NUP214	P27361	MAPK3	S807	P805S	805	Missense	proximal	-2	no	9.430	8.354	EPSD	COSMIC	9.358	Loss
CMGC_MAPK_ERK1_MAPK3_ST	P35658	NUP214	P27361	MAPK3	S940	P933L	933	Missense	distal	-7	no	13.923	14.030	EPSD	COSMIC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P35658	NUP214	P27361	MAPK3	S940	P941H	941	Missense	proximal	1	no	13.923	6.167	EPSD	COSMIC;GDSC;CCLE	9.358	Loss
CMGC_MAPK_ERK1_MAPK3_ST	P35658	NUP214	P27361	MAPK3	T956	R960T	960	Missense	distal	4	no	14.021	14.054	EPSD	COSMIC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P35658	NUP214	P27361	MAPK3	S991	E997K	997	Missense	distal	6	no	9.484	9.408	EPSD	COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P35658	NUP214	P27361	MAPK3	S991	T987I	987	Missense	distal	-4	no	9.484	9.383	EPSD	COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P35658	NUP214	P27361	MAPK3	S991	E995D	995	Missense	distal	4	no	9.484	9.464	EPSD	COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P35658	NUP214	P27361	MAPK3	S991	S993F	993	Missense	proximal	2	no	9.484	9.433	EPSD	COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P35658	NUP214	P27361	MAPK3	S991	S985C	985	Missense	distal	-6	no	9.484	8.925	EPSD	COSMIC	9.358	Loss
CMGC_MAPK_ERK1_MAPK3_ST	P35658	NUP214	P27361	MAPK3	T1021	P1022L	1022	Missense	proximal	1	no	14.464	5.426	EPSD	COSMIC	9.358	Loss
CMGC_MAPK_ERK1_MAPK3_ST	P35658	NUP214	P27361	MAPK3	T1021	R1020H	1020	Missense	proximal	-1	no	14.464	14.467	EPSD	COSMIC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P35658	NUP214	P27361	MAPK3	T1021	V1018M	1018	Missense	distal	-3	no	14.464	14.409	EPSD	COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P35658	NUP214	P27361	MAPK3	S1081	V1075M	1075	Missense	distal	-6	no	14.585	14.493	EPSD	COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P35658	NUP214	P27361	MAPK3	S1081	T1074I	1074	Missense	distal	-7	no	14.585	14.700	EPSD	COSMIC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P35658	NUP214	P27361	MAPK3	T1134	G1140C	1140	Missense	distal	6	no	15.218	14.583	EPSD	COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P35658	NUP214	P27361	MAPK3	T1134	T1137I	1137	Missense	distal	3	no	15.218	15.180	EPSD	COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P35658	NUP214	P27361	MAPK3	T1134	P1132T	1132	Missense	proximal	-2	no	15.218	14.232	EPSD	COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P35658	NUP214	P27361	MAPK3	S1136	G1140C	1140	Missense	distal	4	no	9.690	9.348	EPSD	COSMIC	9.358	Loss
CMGC_MAPK_ERK1_MAPK3_ST	P35658	NUP214	P27361	MAPK3	S1136	T1137I	1137	Missense	proximal	1	no	9.690	9.060	EPSD	COSMIC	9.358	Loss
CMGC_MAPK_ERK1_MAPK3_ST	P35658	NUP214	P27361	MAPK3	S1136	P1132T	1132	Missense	distal	-4	no	9.690	9.660	EPSD	COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P35658	NUP214	P27361	MAPK3	T1150	P1157Q	1157	Missense	distal	7	no	15.675	15.797	EPSD	COSMIC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P35658	NUP214	P27361	MAPK3	T1156	Q1162L	1162	Missense	distal	6	no	14.200	14.154	EPSD	COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P35658	NUP214	P27361	MAPK3	T1156	P1157Q	1157	Missense	proximal	1	no	14.200	6.256	EPSD	COSMIC	9.358	Loss
CMGC_MAPK_ERK1_MAPK3_ST	P35658	NUP214	P27361	MAPK3	T1156	V1158M	1158	Missense	proximal	2	no	14.200	14.182	EPSD	COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P35658	NUP214	P27361	MAPK3	T1178	G1182S	1182	Missense	distal	4	no	12.304	12.465	EPSD	COSMIC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P35658	NUP214	P27361	MAPK3	T1201	S1202P	1202	Missense	proximal	1	no	6.403	15.456	EPSD	COSMIC	9.358	Gain
CMGC_MAPK_ERK1_MAPK3_ST	P35658	NUP214	P27361	MAPK3	T1203	A1206T	1206	Missense	distal	3	no	16.186	16.216	EPSD	COSMIC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P35658	NUP214	P27361	MAPK3	T1203	V1200M	1200	Missense	distal	-3	no	16.186	16.131	EPSD	COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P35658	NUP214	P27361	MAPK3	T1203	S1202P	1202	Missense	proximal	-1	no	16.186	16.192	EPSD	COSMIC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P35658	NUP214	P27361	MAPK3	T1203	S1207F	1207	Missense	distal	4	no	16.186	15.771	EPSD	COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P35658	NUP214	P27361	MAPK3	T1203	S1205L	1205	Missense	proximal	2	no	16.186	16.162	EPSD	COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P35658	NUP214	P27361	MAPK3	S1215	K1212N	1212	Missense	distal	-3	no	11.303	11.310	EPSD	COSMIC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P35658	NUP214	P27361	MAPK3	S1217	K1212N	1212	Missense	distal	-5	no	17.250	17.256	EPSD	COSMIC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P35658	NUP214	P27361	MAPK3	T1231	A1238V	1238	Missense	distal	7	no	15.182	15.154	EPSD	COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P35658	NUP214	P27361	MAPK3	T1243	A1242S	1242	Missense	proximal	-1	no	15.805	15.939	EPSD	COSMIC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P35658	NUP214	P27361	MAPK3	T1243	G1241V	1241	Missense	proximal	-2	no	15.805	16.267	EPSD	COSMIC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P35658	NUP214	P27361	MAPK3	T1243	A1238V	1238	Missense	distal	-5	no	15.805	15.828	EPSD	COSMIC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P35658	NUP214	P27361	MAPK3	T1243	G1241W	1241	Missense	proximal	-2	no	15.805	14.625	EPSD	COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P35658	NUP214	P27361	MAPK3	T1243	T1246A	1246	Missense	distal	3	no	15.805	15.775	EPSD	COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P35658	NUP214	P27361	MAPK3	S1307	A1302T	1302	Missense	distal	-5	no	9.475	9.558	EPSD	COSMIC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P35658	NUP214	P27361	MAPK3	S1307	P1314L	1314	Missense	distal	7	no	9.475	9.668	EPSD	COSMIC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P35658	NUP214	P27361	MAPK3	S1307	P1314S	1314	Missense	distal	7	no	9.475	9.398	EPSD	COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P35658	NUP214	P27361	MAPK3	S1307	T1312N	1312	Missense	distal	5	no	9.475	9.489	EPSD	COSMIC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P35658	NUP214	P27361	MAPK3	S1307	L1310F	1310	Missense	distal	3	no	9.475	9.443	EPSD	COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P35658	NUP214	P27361	MAPK3	T1312	P1314L	1314	Missense	proximal	2	no	14.510	14.489	EPSD	COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P35658	NUP214	P27361	MAPK3	T1312	P1314S	1314	Missense	proximal	2	no	14.510	14.512	EPSD	COSMIC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P35658	NUP214	P27361	MAPK3	T1312	S1307T	1307	Missense	distal	-5	no	14.510	14.494	EPSD	COSMIC;GDSC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P35658	NUP214	P27361	MAPK3	T1312	T1312N	1312	Missense	central	0	yes	14.510	0.000	EPSD	COSMIC	9.358	Loss
CMGC_MAPK_ERK1_MAPK3_ST	P35658	NUP214	P27361	MAPK3	T1312	L1310F	1310	Missense	proximal	-2	no	14.510	13.518	EPSD	COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P35658	NUP214	P27361	MAPK3	T1312	S1315Y	1315	Missense	distal	3	no	14.510	14.480	EPSD	COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P35658	NUP214	P27361	MAPK3	T1568	E1566D	1566	Missense	proximal	-2	no	14.113	14.152	EPSD	COSMIC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P35658	NUP214	P27361	MAPK3	T1568	P1575L	1575	Missense	distal	7	no	14.113	14.305	EPSD	COSMIC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P35658	NUP214	P27361	MAPK3	T1568	S1564F	1564	Missense	distal	-4	no	14.113	13.924	EPSD	COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P35658	NUP214	P27361	MAPK3	T1568	G1573V	1573	Missense	distal	5	no	14.113	13.911	EPSD	COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P35658	NUP214	P27361	MAPK3	S1790	S1789C	1789	Missense	proximal	-1	no	16.879	16.653	EPSD	COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P35658	NUP214	P27361	MAPK3	S1790	T1793A	1793	Missense	distal	3	no	16.879	16.849	EPSD	COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P35658	NUP214	P27361	MAPK3	S1790	G1796V	1796	Missense	distal	6	no	16.879	16.673	EPSD	COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P35658	NUP214	P27361	MAPK3	S1809	Q1814H	1814	Missense	distal	5	no	15.741	15.778	PhosphoSitePlus;EPSD	COSMIC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P35658	NUP214	P27361	MAPK3	S1937	P1943L	1943	Missense	distal	6	no	9.400	9.173	EPSD	COSMIC	9.358	Loss
CMGC_MAPK_ERK1_MAPK3_ST	P35658	NUP214	P27361	MAPK3	S1937	T1944S	1944	Missense	distal	7	no	9.400	9.281	EPSD	COSMIC	9.358	Loss
CMGC_MAPK_ERK1_MAPK3_ST	P35658	NUP214	P27361	MAPK3	T1946	P1943L	1943	Missense	distal	-3	no	10.439	10.354	EPSD	COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P35658	NUP214	P27361	MAPK3	T1946	T1944S	1944	Missense	proximal	-2	no	10.439	10.348	EPSD	COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P35658	NUP214	P27361	MAPK3	T1946	G1945V	1945	Missense	proximal	-1	no	10.439	10.420	EPSD	COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P35658	NUP214	P27361	MAPK3	S1963	P1964L	1964	Missense	proximal	1	no	17.142	8.104	EPSD	COSMIC	9.358	Loss
CMGC_MAPK_ERK1_MAPK3_ST	P35658	NUP214	P27361	MAPK3	S1978	P1974L	1974	Missense	distal	-4	no	15.610	15.498	EPSD	COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P35658	NUP214	P27361	MAPK3	S1978	G1971C	1971	Missense	distal	-7	no	15.610	15.842	EPSD	COSMIC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P35658	NUP214	P27361	MAPK3	S1978	P1979H	1979	Missense	proximal	1	no	15.610	7.854	EPSD	COSMIC	9.358	Loss
CMGC_MAPK_ERK1_MAPK3_ST	P35658	NUP214	P27361	MAPK3	T1981	P1974L	1974	Missense	distal	-7	no	10.100	10.207	EPSD	COSMIC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P35658	NUP214	P27361	MAPK3	T1981	P1986T	1986	Missense	distal	5	no	10.100	10.008	EPSD	COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P35658	NUP214	P27361	MAPK3	T1981	P1979H	1979	Missense	proximal	-2	no	10.100	8.872	EPSD	COSMIC	9.358	Loss
CMGC_MAPK_ERK1_MAPK3_ST	P35658	NUP214	P27361	MAPK3	S1985	P1986T	1986	Missense	proximal	1	no	14.286	5.408	EPSD	COSMIC	9.358	Loss
CMGC_MAPK_ERK1_MAPK3_ST	P35658	NUP214	P27361	MAPK3	S1985	P1979H	1979	Missense	distal	-6	no	14.286	14.206	EPSD	COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P35658	NUP214	P27361	MAPK3	S2002	G2005S	2005	Missense	distal	3	no	16.922	16.937	EPSD	COSMIC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P35658	NUP214	P27361	MAPK3	S2002	G1995S	1995	Missense	distal	-7	no	16.922	16.884	EPSD	COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q15672	TWIST1	P27361	MAPK3	S8	S11L	11	Missense	distal	3	no	14.982	14.950	EPSD	COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q15672	TWIST1	P27361	MAPK3	S11	S11L	11	Missense	central	0	yes	16.222	0.000	EPSD	COSMIC	9.358	Loss
CMGC_MAPK_ERK1_MAPK3_ST	Q15672	TWIST1	P27361	MAPK3	S20	R26W	26	Missense	distal	6	no	9.358	8.535	EPSD	COSMIC	9.358	Loss
CMGC_MAPK_ERK1_MAPK3_ST	Q15672	TWIST1	P27361	MAPK3	S68	R74S	74	Missense	distal	6	no	17.779	18.021	PhosphoSitePlus	COSMIC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q15672	TWIST1	P27361	MAPK3	S68	P66A	66	Missense	proximal	-2	no	17.779	15.428	PhosphoSitePlus	COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q15672	TWIST1	P27361	MAPK3	S99	E104K	104	Missense	distal	5	no	17.724	17.595	EPSD	COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q15672	TWIST1	P27361	MAPK3	S99	P100S	100	Missense	proximal	1	no	17.724	8.670	EPSD	COSMIC	9.358	Loss
CMGC_MAPK_ERK1_MAPK3_ST	Q15672	TWIST1	P27361	MAPK3	S102	E104K	104	Missense	proximal	2	no	10.246	10.239	EPSD	COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q15672	TWIST1	P27361	MAPK3	S102	P100S	100	Missense	proximal	-2	no	10.246	9.170	EPSD	COSMIC	9.358	Loss
CMGC_MAPK_ERK1_MAPK3_ST	Q15672	TWIST1	P27361	MAPK3	S102	T108M	108	Missense	distal	6	no	10.246	9.752	EPSD	COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P28562	DUSP1	P27361	MAPK3	T141	S146T	146	Missense	distal	5	no	12.707	12.572	EPSD	COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P28562	DUSP1	P27361	MAPK3	T141	S140L	140	Missense	proximal	-1	no	12.707	12.619	EPSD	COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P28562	DUSP1	P27361	MAPK3	S296	M302V	302	Missense	distal	6	no	16.534	16.744	EPSD	COSMIC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P28562	DUSP1	P27361	MAPK3	S323	M326T	326	Missense	distal	3	no	14.525	14.574	EPSD	COSMIC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P28562	DUSP1	P27361	MAPK3	S323	A327T	327	Missense	distal	4	no	14.525	14.743	EPSD	COSMIC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P28562	DUSP1	P27361	MAPK3	S323	A319V	319	Missense	distal	-4	no	14.525	14.505	EPSD	COSMIC;GDSC;CCLE	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P28562	DUSP1	P27361	MAPK3	S359	S355R	355	Missense	distal	-4	no	18.543	18.466	EPSD;PhosphoSitePlus	COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P28562	DUSP1	P27361	MAPK3	S359	P360L	360	Missense	proximal	1	no	18.543	9.505	EPSD;PhosphoSitePlus	COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P28562	DUSP1	P27361	MAPK3	S364	P360L	360	Missense	distal	-4	no	19.350	19.237	PhosphoSitePlus;EPSD	COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q92974	ARHGEF2	P27361	MAPK3	S127	D128Y	128	Missense	proximal	1	no	8.747	10.300	EPSD	COSMIC	9.358	Gain
CMGC_MAPK_ERK1_MAPK3_ST	Q92974	ARHGEF2	P27361	MAPK3	S129	S122L	122	Missense	distal	-7	no	9.246	9.391	EPSD	COSMIC	9.358	Gain
CMGC_MAPK_ERK1_MAPK3_ST	Q92974	ARHGEF2	P27361	MAPK3	S163	R168L	168	Missense	distal	5	no	16.999	16.872	EPSD	COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q92974	ARHGEF2	P27361	MAPK3	S163	D161N	161	Missense	proximal	-2	no	16.999	16.586	EPSD	COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q92974	ARHGEF2	P27361	MAPK3	S163	P164L	164	Missense	proximal	1	no	16.999	7.961	EPSD	COSMIC	9.358	Loss
CMGC_MAPK_ERK1_MAPK3_ST	Q92974	ARHGEF2	P27361	MAPK3	S172	S174P	174	Missense	proximal	2	no	9.741	9.739	EPSD	COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q92974	ARHGEF2	P27361	MAPK3	S172	R168L	168	Missense	distal	-4	no	9.741	9.677	EPSD	COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q92974	ARHGEF2	P27361	MAPK3	S172	T175K	175	Missense	distal	3	no	9.741	9.730	EPSD	COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q92974	ARHGEF2	P27361	MAPK3	T455	T455K	455	Missense	central	0	yes	12.419	0.000	EPSD	COSMIC	9.358	Loss
CMGC_MAPK_ERK1_MAPK3_ST	Q92974	ARHGEF2	P27361	MAPK3	T455	M449I	449	Missense	distal	-6	no	12.419	12.442	EPSD	COSMIC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q92974	ARHGEF2	P27361	MAPK3	S648	R642C	642	Missense	distal	-6	no	17.806	17.407	EPSD	COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q92974	ARHGEF2	P27361	MAPK3	S648	S645F	645	Missense	distal	-3	no	17.806	17.664	EPSD	COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q92974	ARHGEF2	P27361	MAPK3	T679	L685V	685	Missense	distal	6	no	15.038	14.956	EPSD;PhosphoSitePlus	COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q92974	ARHGEF2	P27361	MAPK3	S696	D690H	690	Missense	distal	-6	no	15.941	15.837	EPSD	COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q92974	ARHGEF2	P27361	MAPK3	S696	G703A	703	Missense	distal	7	no	15.941	16.148	EPSD	COSMIC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q92974	ARHGEF2	P27361	MAPK3	S733	L731V	731	Missense	proximal	-2	no	18.244	17.974	EPSD	COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q92974	ARHGEF2	P27361	MAPK3	S733	P734Q	734	Missense	proximal	1	no	18.244	10.300	EPSD	COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q92974	ARHGEF2	P27361	MAPK3	S733	S733L	733	Missense	central	0	yes	18.244	0.000	EPSD	COSMIC	9.358	Loss
CMGC_MAPK_ERK1_MAPK3_ST	Q92974	ARHGEF2	P27361	MAPK3	S886	L887F	887	Missense	proximal	1	no	7.286	10.111	EPSD	COSMIC	9.358	Gain
CMGC_MAPK_ERK1_MAPK3_ST	Q92974	ARHGEF2	P27361	MAPK3	S932	P933S	933	Missense	proximal	1	no	14.564	5.510	EPSD	COSMIC	9.358	Loss
CMGC_MAPK_ERK1_MAPK3_ST	Q92974	ARHGEF2	P27361	MAPK3	S932	S932N	932	Missense	central	0	yes	14.564	0.000	EPSD	COSMIC	9.358	Loss
CMGC_MAPK_ERK1_MAPK3_ST	Q92974	ARHGEF2	P27361	MAPK3	S932	E934K	934	Missense	proximal	2	no	14.564	14.556	EPSD	COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q92974	ARHGEF2	P27361	MAPK3	S932	G931V	931	Missense	proximal	-1	no	14.564	14.545	EPSD	COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q92974	ARHGEF2	P27361	MAPK3	S932	R927S	927	Missense	distal	-5	no	14.564	14.609	EPSD	COSMIC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q92974	ARHGEF2	P27361	MAPK3	S932	E926Q	926	Missense	distal	-6	no	14.564	14.429	EPSD	COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q92974	ARHGEF2	P27361	MAPK3	S947	E948Q	948	Missense	proximal	1	no	8.487	9.792	EPSD	COSMIC	9.358	Gain
CMGC_MAPK_ERK1_MAPK3_ST	Q92974	ARHGEF2	P27361	MAPK3	S956	S952R	952	Missense	distal	-4	no	16.965	16.888	EPSD	COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q92974	ARHGEF2	P27361	MAPK3	S956	G951E	951	Missense	distal	-5	no	16.965	16.974	EPSD	COSMIC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q92974	ARHGEF2	P27361	MAPK3	S956	S952T	952	Missense	distal	-4	no	16.965	16.907	EPSD	COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q92974	ARHGEF2	P27361	MAPK3	S956	L955V	955	Missense	proximal	-1	no	16.965	16.969	EPSD	COSMIC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q92974	ARHGEF2	P27361	MAPK3	S960	L955V	955	Missense	distal	-5	no	20.015	19.999	EPSD	COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q15796	SMAD2	P27361	MAPK3	T8	F7S	7	Missense	proximal	-1	no	15.951	16.155	EPSD;PhosphoSitePlus	COSMIC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q15796	SMAD2	P27361	MAPK3	T8	V12L	12	Missense	distal	4	no	15.951	15.970	EPSD;PhosphoSitePlus	COSMIC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q15796	SMAD2	P27361	MAPK3	T8	S2P	2	Missense	distal	-6	no	15.951	15.866	EPSD;PhosphoSitePlus	COSMIC;GDSC;CCLE	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q15796	SMAD2	P27361	MAPK3	T8	S2L	2	Missense	distal	-6	no	15.951	15.619	EPSD;PhosphoSitePlus	COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q15796	SMAD2	P27361	MAPK3	T8	S3F	3	Missense	distal	-5	no	15.951	15.816	EPSD;PhosphoSitePlus	COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q15796	SMAD2	P27361	MAPK3	S47	K53E	53	Missense	distal	6	no	9.541	9.617	EPSD	COSMIC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q15796	SMAD2	P27361	MAPK3	S47	W40G	40	Missense	distal	-7	no	9.541	9.250	EPSD	COSMIC	9.358	Loss
CMGC_MAPK_ERK1_MAPK3_ST	Q15796	SMAD2	P27361	MAPK3	S47	A44T	44	Missense	distal	-3	no	9.541	9.603	EPSD	COSMIC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q15796	SMAD2	P27361	MAPK3	S47	K54T	54	Missense	distal	7	no	9.541	9.485	EPSD	COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q15796	SMAD2	P27361	MAPK3	S47	E42Q	42	Missense	distal	-5	no	9.541	9.523	EPSD	COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q15796	SMAD2	P27361	MAPK3	T172	Y165D	165	Missense	distal	-7	no	13.836	13.760	EPSD	COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q15796	SMAD2	P27361	MAPK3	T172	P177S	177	Missense	distal	5	no	13.836	13.879	EPSD	COSMIC;GDSC;CCLE	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q15796	SMAD2	P27361	MAPK3	T172	R169G	169	Missense	distal	-3	no	13.836	13.841	EPSD	COSMIC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q15796	SMAD2	P27361	MAPK3	T172	Y167C	167	Missense	distal	-5	no	13.836	13.737	EPSD	COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q15796	SMAD2	P27361	MAPK3	T172	H166Q	166	Missense	distal	-6	no	13.836	13.850	EPSD	COSMIC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q15796	SMAD2	P27361	MAPK3	T172	Y165F	165	Missense	distal	-7	no	13.836	13.936	EPSD	COSMIC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q15796	SMAD2	P27361	MAPK3	T220	T220M	220	Missense	central	0	yes	15.000	0.000	EPSD;PhosphoSitePlus	COSMIC;GDSC;CCLE	9.358	Loss
CMGC_MAPK_ERK1_MAPK3_ST	Q15796	SMAD2	P27361	MAPK3	T220	E219K	219	Missense	proximal	-1	no	15.000	14.970	EPSD;PhosphoSitePlus	COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q15796	SMAD2	P27361	MAPK3	T220	P218L	218	Missense	proximal	-2	no	15.000	13.616	EPSD;PhosphoSitePlus	COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q15796	SMAD2	P27361	MAPK3	T220	T220A	220	Missense	central	0	yes	15.000	0.000	EPSD;PhosphoSitePlus	COSMIC	9.358	Loss
CMGC_MAPK_ERK1_MAPK3_ST	Q15796	SMAD2	P27361	MAPK3	T220	P221S	221	Missense	proximal	1	no	15.000	5.947	EPSD;PhosphoSitePlus	COSMIC	9.358	Loss
CMGC_MAPK_ERK1_MAPK3_ST	Q15796	SMAD2	P27361	MAPK3	T220	P218S	218	Missense	proximal	-2	no	15.000	13.924	EPSD;PhosphoSitePlus	COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q15796	SMAD2	P27361	MAPK3	T220	Q213H	213	Missense	distal	-7	no	15.000	14.990	EPSD;PhosphoSitePlus	COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q15796	SMAD2	P27361	MAPK3	T220	P223S	223	Missense	distal	3	no	15.000	14.996	EPSD;PhosphoSitePlus	COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q15796	SMAD2	P27361	MAPK3	S245	D242E	242	Missense	distal	-3	no	20.102	20.105	EPSD;PhosphoSitePlus	COSMIC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q15796	SMAD2	P27361	MAPK3	S245	L249V	249	Missense	distal	4	no	20.102	20.082	EPSD;PhosphoSitePlus	COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q15796	SMAD2	P27361	MAPK3	S245	E248Q	248	Missense	distal	3	no	20.102	20.093	EPSD;PhosphoSitePlus	COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q15796	SMAD2	P27361	MAPK3	S245	S245C	245	Missense	central	0	yes	20.102	0.000	EPSD;PhosphoSitePlus	COSMIC	9.358	Loss
CMGC_MAPK_ERK1_MAPK3_ST	Q15796	SMAD2	P27361	MAPK3	S245	P246L	246	Missense	proximal	1	no	20.102	11.064	EPSD;PhosphoSitePlus	COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q15796	SMAD2	P27361	MAPK3	S245	S240R	240	Missense	distal	-5	no	20.102	20.056	EPSD;PhosphoSitePlus	COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q15796	SMAD2	P27361	MAPK3	S250	S255F	255	Missense	distal	5	no	17.689	17.264	EPSD;PhosphoSitePlus	COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q15796	SMAD2	P27361	MAPK3	S250	L249V	249	Missense	proximal	-1	no	17.689	17.694	EPSD;PhosphoSitePlus	COSMIC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q15796	SMAD2	P27361	MAPK3	S250	E248Q	248	Missense	proximal	-2	no	17.689	17.571	EPSD;PhosphoSitePlus	COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q15796	SMAD2	P27361	MAPK3	S250	S245C	245	Missense	distal	-5	no	17.689	17.527	EPSD;PhosphoSitePlus	COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q15796	SMAD2	P27361	MAPK3	S250	P246L	246	Missense	distal	-4	no	17.689	17.576	EPSD;PhosphoSitePlus	COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q15796	SMAD2	P27361	MAPK3	S255	S255F	255	Missense	central	0	yes	18.277	0.000	PhosphoSitePlus;EPSD	COSMIC	9.358	Loss
CMGC_MAPK_ERK1_MAPK3_ST	Q15796	SMAD2	P27361	MAPK3	S255	L249V	249	Missense	distal	-6	no	18.277	18.279	PhosphoSitePlus;EPSD	COSMIC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q15796	SMAD2	P27361	MAPK3	S255	E248Q	248	Missense	distal	-7	no	18.277	18.327	PhosphoSitePlus;EPSD	COSMIC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q15796	SMAD2	P27361	MAPK3	S417	M416V	416	Missense	proximal	-1	no	9.485	9.556	EPSD	COSMIC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q15796	SMAD2	P27361	MAPK3	S417	M416R	416	Missense	proximal	-1	no	9.485	9.598	EPSD	COSMIC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q15796	SMAD2	P27361	MAPK3	S417	R410G	410	Missense	distal	-7	no	9.485	9.440	EPSD	COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q15796	SMAD2	P27361	MAPK3	S417	K420Q	420	Missense	distal	3	no	9.485	9.487	EPSD	COSMIC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q15796	SMAD2	P27361	MAPK3	S417	S417N	417	Missense	central	0	yes	9.485	0.000	EPSD	COSMIC	9.358	Loss
CMGC_MAPK_ERK1_MAPK3_ST	Q15796	SMAD2	P27361	MAPK3	S417	T413N	413	Missense	distal	-4	no	9.485	9.482	EPSD	COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q15796	SMAD2	P27361	MAPK3	T454	D450H	450	Missense	distal	-4	no	9.423	9.396	EPSD	COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q15796	SMAD2	P27361	MAPK3	T454	G457R	457	Missense	distal	3	no	9.423	9.417	EPSD	COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q15796	SMAD2	P27361	MAPK3	T454	P459H	459	Missense	distal	5	no	9.423	9.358	EPSD	COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q15796	SMAD2	P27361	MAPK3	S458	R462C	462	Missense	distal	4	no	15.165	14.808	EPSD	COSMIC;GDSC;CCLE	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q15796	SMAD2	P27361	MAPK3	S458	C463F	463	Missense	distal	5	no	15.165	15.264	EPSD	COSMIC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q15796	SMAD2	P27361	MAPK3	S458	G457R	457	Missense	proximal	-1	no	15.165	15.190	EPSD	COSMIC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q15796	SMAD2	P27361	MAPK3	S458	S465I	465	Missense	distal	7	no	15.165	15.564	EPSD	COSMIC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q15796	SMAD2	P27361	MAPK3	S458	C463Y	463	Missense	distal	5	no	15.165	15.473	EPSD	COSMIC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q15796	SMAD2	P27361	MAPK3	S458	S465N	465	Missense	distal	7	no	15.165	15.331	EPSD	COSMIC;GDSC;CCLE	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q15796	SMAD2	P27361	MAPK3	S458	P459H	459	Missense	proximal	1	no	15.165	7.410	EPSD	COSMIC	9.358	Loss
CMGC_MAPK_ERK1_MAPK3_ST	Q15796	SMAD2	P27361	MAPK3	S458	S465R	465	Missense	distal	7	no	15.165	15.335	EPSD	COSMIC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q15796	SMAD2	P27361	MAPK3	S458	S464L	464	Missense	distal	6	no	15.165	14.809	EPSD	COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q15796	SMAD2	P27361	MAPK3	S464	R462C	462	Missense	proximal	-2	no	9.782	7.666	EPSD	COSMIC;GDSC;CCLE	9.358	Loss
CMGC_MAPK_ERK1_MAPK3_ST	Q15796	SMAD2	P27361	MAPK3	S464	C463F	463	Missense	proximal	-1	no	9.782	9.805	EPSD	COSMIC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q15796	SMAD2	P27361	MAPK3	S464	G457R	457	Missense	distal	-7	no	9.782	9.827	EPSD	COSMIC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q15796	SMAD2	P27361	MAPK3	S464	S465I	465	Missense	proximal	1	no	9.782	9.328	EPSD	COSMIC	9.358	Loss
CMGC_MAPK_ERK1_MAPK3_ST	Q15796	SMAD2	P27361	MAPK3	S464	C463Y	463	Missense	proximal	-1	no	9.782	9.932	EPSD	COSMIC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q15796	SMAD2	P27361	MAPK3	S464	S465N	465	Missense	proximal	1	no	9.782	4.747	EPSD	COSMIC;GDSC;CCLE	9.358	Loss
CMGC_MAPK_ERK1_MAPK3_ST	Q15796	SMAD2	P27361	MAPK3	S464	P459H	459	Missense	distal	-5	no	9.782	9.751	EPSD	COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q15796	SMAD2	P27361	MAPK3	S464	S465R	465	Missense	proximal	1	no	9.782	9.335	EPSD	COSMIC	9.358	Loss
CMGC_MAPK_ERK1_MAPK3_ST	Q15796	SMAD2	P27361	MAPK3	S464	S464L	464	Missense	central	0	yes	9.782	0.000	EPSD	COSMIC	9.358	Loss
CMGC_MAPK_ERK1_MAPK3_ST	P16144	ITGB4	P27361	MAPK3	S7	G3R	3	Missense	distal	-4	no	14.938	14.900	EPSD	COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P16144	ITGB4	P27361	MAPK3	S7	A10D	10	Missense	distal	3	no	14.938	14.972	EPSD	COSMIC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P16144	ITGB4	P27361	MAPK3	S99	S102P	102	Missense	distal	3	no	9.797	9.802	EPSD	COSMIC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P16144	ITGB4	P27361	MAPK3	S99	T94I	94	Missense	distal	-5	no	9.797	9.718	EPSD	COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P16144	ITGB4	P27361	MAPK3	S102	S102P	102	Missense	central	0	yes	16.331	0.000	EPSD	COSMIC	9.358	Loss
CMGC_MAPK_ERK1_MAPK3_ST	P16144	ITGB4	P27361	MAPK3	S102	V108A	108	Missense	distal	6	no	16.331	16.244	EPSD	COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P16144	ITGB4	P27361	MAPK3	S202	N205S	205	Missense	distal	3	no	12.834	12.855	EPSD	COSMIC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P16144	ITGB4	P27361	MAPK3	S202	K204N	204	Missense	proximal	2	no	12.834	12.833	EPSD	COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P16144	ITGB4	P27361	MAPK3	S377	A374S	374	Missense	distal	-3	no	17.332	17.424	EPSD	COSMIC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P16144	ITGB4	P27361	MAPK3	S377	T383I	383	Missense	distal	6	no	17.332	16.917	EPSD	COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P16144	ITGB4	P27361	MAPK3	S397	E404K	404	Missense	distal	7	no	9.948	10.019	EPSD	COSMIC;GDSC;CCLE	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P16144	ITGB4	P27361	MAPK3	S397	T393M	393	Missense	distal	-4	no	9.948	9.826	EPSD	COSMIC;GDSC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P16144	ITGB4	P27361	MAPK3	S397	R401Q	401	Missense	distal	4	no	9.948	9.904	EPSD	COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P16144	ITGB4	P27361	MAPK3	S397	H399Y	399	Missense	proximal	2	no	9.948	9.941	EPSD	COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P16144	ITGB4	P27361	MAPK3	S397	E404Q	404	Missense	distal	7	no	9.948	10.043	EPSD	COSMIC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P16144	ITGB4	P27361	MAPK3	S1345	G1340W	1340	Missense	distal	-5	no	10.061	9.905	EPSD	COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P16144	ITGB4	P27361	MAPK3	S1356	V1353I	1353	Missense	distal	-3	no	16.245	16.206	PhosphoSitePlus	COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P16144	ITGB4	P27361	MAPK3	S1360	V1353I	1353	Missense	distal	-7	no	10.739	10.781	EPSD	COSMIC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P16144	ITGB4	P27361	MAPK3	S1360	V1365I	1365	Missense	distal	5	no	10.739	10.613	EPSD	COSMIC;GDSC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P16144	ITGB4	P27361	MAPK3	S1474	H1472Y	1472	Missense	proximal	-2	no	16.072	15.990	EPSD	COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P16144	ITGB4	P27361	MAPK3	S1474	V1481M	1481	Missense	distal	7	no	16.072	16.204	EPSD	COSMIC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P16144	ITGB4	P27361	MAPK3	S1474	V1477M	1477	Missense	distal	3	no	16.072	16.047	EPSD	COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P16144	ITGB4	P27361	MAPK3	S1653	S1656L	1656	Missense	distal	3	no	15.774	15.742	EPSD	COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P16144	ITGB4	P27361	MAPK3	S1653	L1657M	1657	Missense	distal	4	no	15.774	15.599	EPSD	COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P16144	ITGB4	P27361	MAPK3	S1653	L1647M	1647	Missense	distal	-6	no	15.774	15.684	EPSD	COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P16144	ITGB4	P27361	MAPK3	S1653	P1654T	1654	Missense	proximal	1	no	15.774	6.897	EPSD	COSMIC	9.358	Loss
CMGC_MAPK_ERK1_MAPK3_ST	P16144	ITGB4	P27361	MAPK3	S1696	R1700W	1700	Missense	distal	4	no	14.845	14.378	EPSD	COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P16144	ITGB4	P27361	MAPK3	S1696	R1691W	1691	Missense	distal	-5	no	14.845	14.691	EPSD	COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P16144	ITGB4	P27361	MAPK3	S1696	E1698K	1698	Missense	proximal	2	no	14.845	14.838	EPSD	COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P16144	ITGB4	P27361	MAPK3	S1696	P1697S	1697	Missense	proximal	1	no	14.845	5.792	EPSD	COSMIC;GDSC	9.358	Loss
CMGC_MAPK_ERK1_MAPK3_ST	P16144	ITGB4	P27361	MAPK3	T1793	R1794P	1794	Missense	proximal	1	no	7.477	16.978	EPSD	COSMIC;CCLE	9.358	Gain
CMGC_MAPK_ERK1_MAPK3_ST	P16144	ITGB4	P27361	MAPK3	T1804	S1802R	1802	Missense	proximal	-2	no	10.793	10.469	EPSD	COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P16144	ITGB4	P27361	MAPK3	T1804	Q1798H	1798	Missense	distal	-6	no	10.793	10.779	EPSD	COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P16144	ITGB4	P27361	MAPK3	S1808	S1802R	1802	Missense	distal	-6	no	9.657	9.496	EPSD	COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	O95817	BAG3	P27361	MAPK3	S173	R170L	170	Missense	distal	-3	no	15.221	15.183	EPSD	COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	O95817	BAG3	P27361	MAPK3	S183	P189L	189	Missense	distal	6	no	9.410	9.184	EPSD	COSMIC;GDSC;CCLE	9.358	Loss
CMGC_MAPK_ERK1_MAPK3_ST	O95817	BAG3	P27361	MAPK3	S198	Y205C	205	Missense	distal	7	no	9.281	9.638	EPSD	COSMIC	9.358	Gain
CMGC_MAPK_ERK1_MAPK3_ST	O95817	BAG3	P27361	MAPK3	S264	R261W	261	Missense	distal	-3	no	13.797	13.630	EPSD	COSMIC;CCLE	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	O95817	BAG3	P27361	MAPK3	S264	P265L	265	Missense	proximal	1	no	13.797	4.759	EPSD	COSMIC	9.358	Loss
CMGC_MAPK_ERK1_MAPK3_ST	O95817	BAG3	P27361	MAPK3	S264	S269F	269	Missense	distal	5	no	13.797	13.373	EPSD	COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	O95817	BAG3	P27361	MAPK3	S264	R258W	258	Missense	distal	-6	no	13.797	13.275	EPSD	COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	O95817	BAG3	P27361	MAPK3	S279	S275I	275	Missense	distal	-4	no	16.045	15.885	EPSD	COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	O95817	BAG3	P27361	MAPK3	S279	R282K	282	Missense	distal	3	no	16.045	16.043	EPSD	COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	O95817	BAG3	P27361	MAPK3	S284	R282K	282	Missense	proximal	-2	no	9.560	8.620	EPSD	COSMIC	9.358	Loss
CMGC_MAPK_ERK1_MAPK3_ST	O95817	BAG3	P27361	MAPK3	T285	R282K	282	Missense	distal	-3	no	16.402	16.389	PhosphoSitePlus;EPSD	COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	O95817	BAG3	P27361	MAPK3	S289	R282K	282	Missense	distal	-7	no	16.568	16.569	EPSD;PhosphoSitePlus	COSMIC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	O95817	BAG3	P27361	MAPK3	S377	P376S	376	Missense	proximal	-1	no	15.872	15.866	EPSD	COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	O95817	BAG3	P27361	MAPK3	S377	P375L	375	Missense	proximal	-2	no	15.872	14.488	EPSD	COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	O95817	BAG3	P27361	MAPK3	T406	A413V	413	Missense	distal	7	no	13.749	13.721	EPSD	COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	O95817	BAG3	P27361	MAPK3	T406	E404K	404	Missense	proximal	-2	no	13.749	13.055	EPSD	COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	O95817	BAG3	P27361	MAPK3	T406	A405T	405	Missense	proximal	-1	no	13.749	13.852	EPSD	COSMIC;GDSC;CCLE	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	O95817	BAG3	P27361	MAPK3	T566	S564N	564	Missense	proximal	-2	no	10.269	9.324	EPSD	COSMIC	9.358	Loss
CMGC_MAPK_ERK1_MAPK3_ST	O95817	BAG3	P27361	MAPK3	T568	A574V	574	Missense	distal	6	no	18.226	18.313	EPSD	COSMIC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	O95817	BAG3	P27361	MAPK3	T568	S564N	564	Missense	distal	-4	no	18.226	18.165	EPSD	COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P20339	RAB5A	P27361	MAPK3	S3	R4P	4	Missense	proximal	1	no	4.080	13.581	EPSD	COSMIC	9.358	Gain
CMGC_MAPK_ERK1_MAPK3_ST	P20339	RAB5A	P27361	MAPK3	S123	P124L	124	Missense	proximal	1	no	14.916	5.878	PhosphoSitePlus	COSMIC	9.358	Loss
CMGC_MAPK_ERK1_MAPK3_ST	P20339	RAB5A	P27361	MAPK3	T202	D200G	200	Missense	proximal	-2	no	11.081	10.572	EPSD	COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P20339	RAB5A	P27361	MAPK3	T205	D200G	200	Missense	distal	-5	no	11.801	11.792	EPSD	COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q15648	MED1	P27361	MAPK3	S18	M16I	16	Missense	proximal	-2	no	9.100	10.015	EPSD	COSMIC	9.358	Gain
CMGC_MAPK_ERK1_MAPK3_ST	Q15648	MED1	P27361	MAPK3	T212	L211R	211	Missense	proximal	-1	no	15.272	15.319	EPSD	COSMIC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q15648	MED1	P27361	MAPK3	S238	N245S	245	Missense	distal	7	no	16.950	16.784	EPSD	COSMIC;GDSC;CCLE	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q15648	MED1	P27361	MAPK3	S434	G436V	436	Missense	proximal	2	no	15.651	15.642	EPSD	COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q15648	MED1	P27361	MAPK3	S448	R449H	449	Missense	proximal	1	no	7.622	9.367	EPSD	COSMIC	9.358	Gain
CMGC_MAPK_ERK1_MAPK3_ST	Q15648	MED1	P27361	MAPK3	T522	D521N	521	Missense	proximal	-1	no	13.472	13.470	EPSD	COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q15648	MED1	P27361	MAPK3	S545	P542Q	542	Missense	distal	-3	no	15.497	15.443	EPSD	COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q15648	MED1	P27361	MAPK3	T562	T564I	564	Missense	proximal	2	no	15.389	15.365	EPSD	COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q15648	MED1	P27361	MAPK3	T562	P568Q	568	Missense	distal	6	no	15.389	15.208	EPSD	COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q15648	MED1	P27361	MAPK3	T562	P568S	568	Missense	distal	6	no	15.389	15.519	EPSD	COSMIC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q15648	MED1	P27361	MAPK3	T562	P563T	563	Missense	proximal	1	no	15.389	6.512	EPSD	COSMIC	9.358	Loss
CMGC_MAPK_ERK1_MAPK3_ST	Q15648	MED1	P27361	MAPK3	S621	T623P	623	Missense	proximal	2	no	15.019	15.028	EPSD	COSMIC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q15648	MED1	P27361	MAPK3	S621	G614E	614	Missense	distal	-7	no	15.019	15.014	EPSD	COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q15648	MED1	P27361	MAPK3	T623	T623P	623	Missense	central	0	yes	15.231	0.000	EPSD	COSMIC	9.358	Loss
CMGC_MAPK_ERK1_MAPK3_ST	Q15648	MED1	P27361	MAPK3	T628	T623P	623	Missense	distal	-5	no	15.844	15.855	EPSD	COSMIC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q15648	MED1	P27361	MAPK3	S675	S673F	673	Missense	proximal	-2	no	16.204	14.904	EPSD	COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q15648	MED1	P27361	MAPK3	T735	H737Y	737	Missense	proximal	2	no	14.724	14.717	EPSD	COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q15648	MED1	P27361	MAPK3	T739	H737Y	737	Missense	proximal	-2	no	13.584	13.502	EPSD	COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q15648	MED1	P27361	MAPK3	T805	D798N	798	Missense	distal	-7	no	15.425	15.449	EPSD	COSMIC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q15648	MED1	P27361	MAPK3	T805	S810C	810	Missense	distal	5	no	15.425	14.902	EPSD	COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q15648	MED1	P27361	MAPK3	S848	L841V	841	Missense	distal	-7	no	15.619	15.623	EPSD	COSMIC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q15648	MED1	P27361	MAPK3	S848	L841F	841	Missense	distal	-7	no	15.619	15.693	EPSD	COSMIC;GDSC;CCLE	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q15648	MED1	P27361	MAPK3	T998	G993E	993	Missense	distal	-5	no	14.578	14.587	EPSD	COSMIC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q15648	MED1	P27361	MAPK3	T998	T998I	998	Missense	central	0	yes	14.578	0.000	EPSD	COSMIC	9.358	Loss
CMGC_MAPK_ERK1_MAPK3_ST	Q15648	MED1	P27361	MAPK3	T998	S1000F	1000	Missense	proximal	2	no	14.578	14.528	EPSD	COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q15648	MED1	P27361	MAPK3	S1021	P1022Q	1022	Missense	proximal	1	no	15.783	7.839	EPSD	COSMIC	9.358	Loss
CMGC_MAPK_ERK1_MAPK3_ST	Q15648	MED1	P27361	MAPK3	S1023	P1022Q	1022	Missense	proximal	-1	no	9.492	9.405	EPSD	COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q15648	MED1	P27361	MAPK3	S1036	S1042L	1042	Missense	distal	6	no	10.136	9.779	EPSD	COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q15648	MED1	P27361	MAPK3	S1042	G1044C	1044	Missense	proximal	2	no	17.902	17.857	EPSD	COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q15648	MED1	P27361	MAPK3	S1042	S1042L	1042	Missense	central	0	yes	17.902	0.000	EPSD	COSMIC	9.358	Loss
CMGC_MAPK_ERK1_MAPK3_ST	Q15648	MED1	P27361	MAPK3	S1045	G1044C	1044	Missense	proximal	-1	no	9.698	9.537	EPSD	COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q15648	MED1	P27361	MAPK3	S1045	P1052F	1052	Missense	distal	7	no	9.698	10.112	EPSD	COSMIC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q15648	MED1	P27361	MAPK3	S1045	P1052S	1052	Missense	distal	7	no	9.698	9.621	EPSD	COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q15648	MED1	P27361	MAPK3	S1045	S1042L	1042	Missense	distal	-3	no	9.698	9.622	EPSD	COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q15648	MED1	P27361	MAPK3	T1051	G1044C	1044	Missense	distal	-7	no	14.190	14.422	EPSD	COSMIC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q15648	MED1	P27361	MAPK3	T1051	P1052F	1052	Missense	proximal	1	no	14.190	7.976	EPSD	COSMIC	9.358	Loss
CMGC_MAPK_ERK1_MAPK3_ST	Q15648	MED1	P27361	MAPK3	T1051	P1052S	1052	Missense	proximal	1	no	14.190	5.137	EPSD	COSMIC	9.358	Loss
CMGC_MAPK_ERK1_MAPK3_ST	Q15648	MED1	P27361	MAPK3	T1057	P1052F	1052	Missense	distal	-5	no	14.005	13.876	EPSD	COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q15648	MED1	P27361	MAPK3	T1057	P1052S	1052	Missense	distal	-5	no	14.005	14.010	EPSD	COSMIC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q15648	MED1	P27361	MAPK3	S1156	P1157A	1157	Missense	proximal	1	no	16.897	7.658	EPSD	COSMIC	9.358	Loss
CMGC_MAPK_ERK1_MAPK3_ST	Q15648	MED1	P27361	MAPK3	S1207	G1214E	1214	Missense	distal	7	no	14.894	14.859	EPSD	COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q15648	MED1	P27361	MAPK3	T1215	G1214E	1214	Missense	proximal	-1	no	16.152	16.193	EPSD	COSMIC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q15648	MED1	P27361	MAPK3	T1215	P1217L	1217	Missense	proximal	2	no	16.152	16.130	EPSD	COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q15648	MED1	P27361	MAPK3	S1223	P1217L	1217	Missense	distal	-6	no	15.688	15.441	EPSD	COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q15648	MED1	P27361	MAPK3	S1223	G1228D	1228	Missense	distal	5	no	15.688	15.711	EPSD	COSMIC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q15648	MED1	P27361	MAPK3	T1259	P1260S	1260	Missense	proximal	1	no	14.469	5.416	EPSD	COSMIC	9.358	Loss
CMGC_MAPK_ERK1_MAPK3_ST	Q15648	MED1	P27361	MAPK3	S1271	S1272F	1272	Missense	proximal	1	no	6.822	9.662	EPSD	COSMIC	9.358	Gain
CMGC_MAPK_ERK1_MAPK3_ST	Q15648	MED1	P27361	MAPK3	S1272	S1272F	1272	Missense	central	0	yes	10.362	0.000	EPSD	COSMIC	9.358	Loss
CMGC_MAPK_ERK1_MAPK3_ST	Q15648	MED1	P27361	MAPK3	S1272	A1268T	1268	Missense	distal	-4	no	10.362	10.435	EPSD	COSMIC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q15648	MED1	P27361	MAPK3	S1272	S1278A	1278	Missense	distal	6	no	10.362	9.836	EPSD	COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q15648	MED1	P27361	MAPK3	S1294	S1290Y	1290	Missense	distal	-4	no	15.910	15.807	EPSD	COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q15648	MED1	P27361	MAPK3	T1440	R1445C	1445	Missense	distal	5	no	13.736	13.356	EPSD	COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q15648	MED1	P27361	MAPK3	S1447	R1445C	1445	Missense	proximal	-2	no	16.294	14.178	EPSD	COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q15648	MED1	P27361	MAPK3	S1449	R1445C	1445	Missense	distal	-4	no	9.714	9.553	EPSD	COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q15648	MED1	P27361	MAPK3	S1453	P1458S	1458	Missense	distal	5	no	17.235	17.278	EPSD	COSMIC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q15648	MED1	P27361	MAPK3	T1457	P1458S	1458	Missense	proximal	1	no	14.176	5.122	PhosphoSitePlus;EPSD	COSMIC	9.358	Loss
CMGC_MAPK_ERK1_MAPK3_ST	Q15648	MED1	P27361	MAPK3	S1479	E1473D	1473	Missense	distal	-6	no	16.450	16.406	EPSD	COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q15648	MED1	P27361	MAPK3	S1479	S1479N	1479	Missense	central	0	yes	16.450	0.000	EPSD	COSMIC	9.358	Loss
CMGC_MAPK_ERK1_MAPK3_ST	Q15648	MED1	P27361	MAPK3	S1532	S1525F	1525	Missense	distal	-7	no	9.482	9.701	EPSD	COSMIC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q15648	MED1	P27361	MAPK3	S1532	H1526Y	1526	Missense	distal	-6	no	9.482	9.393	EPSD	COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q15648	MED1	P27361	MAPK3	S1558	P1562S	1562	Missense	distal	4	no	10.298	10.347	EPSD	COSMIC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q15648	MED1	P27361	MAPK3	S1561	P1562S	1562	Missense	proximal	1	no	17.939	8.885	EPSD	COSMIC	9.358	Loss
CMGC_MAPK_ERK1_MAPK3_ST	O75582	RPS6KA5	P27361	MAPK3	S253	G251R	251	Missense	proximal	-2	no	14.937	15.653	EPSD	COSMIC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	O75582	RPS6KA5	P27361	MAPK3	S253	E260K	260	Missense	distal	7	no	14.937	15.008	EPSD	COSMIC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	O75582	RPS6KA5	P27361	MAPK3	S360	A362T	362	Missense	proximal	2	no	17.950	17.977	PhosphoSitePlus;EPSD	COSMIC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	O75582	RPS6KA5	P27361	MAPK3	S360	P357S	357	Missense	distal	-3	no	17.950	17.941	PhosphoSitePlus;EPSD	COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	O75582	RPS6KA5	P27361	MAPK3	S360	E354K	354	Missense	distal	-6	no	17.950	17.808	PhosphoSitePlus;EPSD	COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	O75582	RPS6KA5	P27361	MAPK3	S367	A362T	362	Missense	distal	-5	no	9.675	9.758	EPSD	COSMIC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	O75582	RPS6KA5	P27361	MAPK3	T581	P582L	582	Missense	proximal	1	no	17.145	8.107	EPSD;PhosphoSitePlus	COSMIC	9.358	Loss
CMGC_MAPK_ERK1_MAPK3_ST	O75582	RPS6KA5	P27361	MAPK3	T581	P578H	578	Missense	distal	-3	no	17.145	17.105	EPSD;PhosphoSitePlus	COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	O75582	RPS6KA5	P27361	MAPK3	T581	P578S	578	Missense	distal	-3	no	17.145	17.137	EPSD;PhosphoSitePlus	COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	O75582	RPS6KA5	P27361	MAPK3	T700	M699T	699	Missense	proximal	-1	no	16.688	16.813	EPSD	COSMIC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	O75582	RPS6KA5	P27361	MAPK3	S768	E761K	761	Missense	distal	-7	no	9.457	9.508	EPSD	COSMIC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	O75582	RPS6KA5	P27361	MAPK3	S768	S766P	766	Missense	proximal	-2	no	9.457	10.533	EPSD	COSMIC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	O75582	RPS6KA5	P27361	MAPK3	S770	S766P	766	Missense	distal	-4	no	10.362	10.334	EPSD	COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	O75582	RPS6KA5	P27361	MAPK3	T793	D787N	787	Missense	distal	-6	no	9.895	9.833	EPSD	COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P29590	PML	P27361	MAPK3	T28	P26S	26	Missense	proximal	-2	no	18.543	17.467	PhosphoSitePlus;EPSD	COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P29590	PML	P27361	MAPK3	S30	P26S	26	Missense	distal	-4	no	10.710	10.737	EPSD	COSMIC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P29590	PML	P27361	MAPK3	S38	R44Q	44	Missense	distal	6	no	17.527	17.458	EPSD;PhosphoSitePlus	COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P29590	PML	P27361	MAPK3	S40	R44Q	44	Missense	distal	4	no	16.781	16.737	EPSD;PhosphoSitePlus	COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P29590	PML	P27361	MAPK3	T196	T198M	198	Missense	proximal	2	no	16.585	16.553	EPSD	COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P29590	PML	P27361	MAPK3	T196	N193S	193	Missense	distal	-3	no	16.585	16.630	EPSD	COSMIC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P29590	PML	P27361	MAPK3	T482	Q483P	483	Missense	proximal	1	no	6.684	14.628	EPSD	COSMIC	9.358	Gain
CMGC_MAPK_ERK1_MAPK3_ST	P29590	PML	P27361	MAPK3	S505	P506L	506	Missense	proximal	1	no	14.608	5.570	EPSD	COSMIC	9.358	Loss
CMGC_MAPK_ERK1_MAPK3_ST	P29590	PML	P27361	MAPK3	T513	S514P	514	Missense	proximal	1	no	9.007	18.061	EPSD	COSMIC	9.358	Gain
CMGC_MAPK_ERK1_MAPK3_ST	P29590	PML	P27361	MAPK3	S518	S514P	514	Missense	distal	-4	no	16.965	16.938	EPSD	COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P29590	PML	P27361	MAPK3	S561	S562P	562	Missense	proximal	1	no	4.824	13.877	EPSD	COSMIC	9.358	Gain
CMGC_MAPK_ERK1_MAPK3_ST	P29590	PML	P27361	MAPK3	S583	S583L	583	Missense	central	0	yes	9.745	0.000	EPSD	COSMIC	9.358	Loss
CMGC_MAPK_ERK1_MAPK3_ST	P29590	PML	P27361	MAPK3	S804	S804G	804	Missense	central	0	yes	10.169	0.000	EPSD	COSMIC	9.358	Loss
CMGC_MAPK_ERK1_MAPK3_ST	P29590	PML	P27361	MAPK3	T867	G871D	871	Missense	distal	4	no	17.550	17.591	EPSD	COSMIC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P29590	PML	P27361	MAPK3	T867	R872H	872	Missense	distal	5	no	17.550	17.586	EPSD	COSMIC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P29590	PML	P27361	MAPK3	S879	Q881R	881	Missense	proximal	2	no	11.285	11.294	EPSD	COSMIC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P29590	PML	P27361	MAPK3	S879	R872H	872	Missense	distal	-7	no	11.285	11.273	EPSD	COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	O15027	SEC16A	P27361	MAPK3	T19	A21V	21	Missense	proximal	2	no	16.670	16.683	EPSD	COSMIC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	O15027	SEC16A	P27361	MAPK3	T19	G16C	16	Missense	distal	-3	no	16.670	16.525	EPSD	COSMIC;CCLE	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	O15027	SEC16A	P27361	MAPK3	T19	A22V	22	Missense	distal	3	no	16.670	16.676	EPSD	COSMIC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	O15027	SEC16A	P27361	MAPK3	T19	G16S	16	Missense	distal	-3	no	16.670	16.702	EPSD	COSMIC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	O15027	SEC16A	P27361	MAPK3	S23	A21V	21	Missense	proximal	-2	no	16.737	17.434	EPSD	COSMIC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	O15027	SEC16A	P27361	MAPK3	S23	G16C	16	Missense	distal	-7	no	16.737	16.969	EPSD	COSMIC;CCLE	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	O15027	SEC16A	P27361	MAPK3	S23	A22V	22	Missense	proximal	-1	no	16.737	16.787	EPSD	COSMIC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	O15027	SEC16A	P27361	MAPK3	S23	G16S	16	Missense	distal	-7	no	16.737	16.700	EPSD	COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	O15027	SEC16A	P27361	MAPK3	S23	P27S	27	Missense	distal	4	no	16.737	16.786	EPSD	COSMIC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	O15027	SEC16A	P27361	MAPK3	S25	A21V	21	Missense	distal	-4	no	11.977	11.956	EPSD	COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	O15027	SEC16A	P27361	MAPK3	S25	Q32K	32	Missense	distal	7	no	11.977	11.952	EPSD	COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	O15027	SEC16A	P27361	MAPK3	S25	A22V	22	Missense	distal	-3	no	11.977	11.996	EPSD	COSMIC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	O15027	SEC16A	P27361	MAPK3	S25	P27S	27	Missense	proximal	2	no	11.977	11.978	EPSD	COSMIC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	O15027	SEC16A	P27361	MAPK3	S122	P128L	128	Missense	distal	6	no	11.074	10.848	EPSD	COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	O15027	SEC16A	P27361	MAPK3	T123	P128L	128	Missense	distal	5	no	9.400	9.172	EPSD	COSMIC	9.358	Loss
CMGC_MAPK_ERK1_MAPK3_ST	O15027	SEC16A	P27361	MAPK3	S136	P143L	143	Missense	distal	7	no	13.354	13.546	EPSD	COSMIC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	O15027	SEC16A	P27361	MAPK3	S153	S153F	153	Missense	central	0	yes	9.913	0.000	EPSD	COSMIC	9.358	Loss
CMGC_MAPK_ERK1_MAPK3_ST	O15027	SEC16A	P27361	MAPK3	S153	A160T	160	Missense	distal	7	no	9.913	9.686	EPSD	COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	O15027	SEC16A	P27361	MAPK3	S153	R150W	150	Missense	distal	-3	no	9.913	9.746	EPSD	COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	O15027	SEC16A	P27361	MAPK3	S153	E148K	148	Missense	distal	-5	no	9.913	9.901	EPSD	COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	O15027	SEC16A	P27361	MAPK3	S153	P151S	151	Missense	proximal	-2	no	9.913	8.837	EPSD	COSMIC	9.358	Loss
CMGC_MAPK_ERK1_MAPK3_ST	O15027	SEC16A	P27361	MAPK3	S153	L159F	159	Missense	distal	6	no	9.913	9.556	EPSD	COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	O15027	SEC16A	P27361	MAPK3	S164	P165S	165	Missense	proximal	1	no	14.950	5.896	EPSD	COSMIC;GDSC	9.358	Loss
CMGC_MAPK_ERK1_MAPK3_ST	O15027	SEC16A	P27361	MAPK3	S164	A160T	160	Missense	distal	-4	no	14.950	15.023	EPSD	COSMIC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	O15027	SEC16A	P27361	MAPK3	S164	R161W	161	Missense	distal	-3	no	14.950	14.782	EPSD	COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	O15027	SEC16A	P27361	MAPK3	S164	S164R	164	Missense	central	0	yes	14.950	0.000	EPSD	COSMIC	9.358	Loss
CMGC_MAPK_ERK1_MAPK3_ST	O15027	SEC16A	P27361	MAPK3	S164	L159F	159	Missense	distal	-5	no	14.950	14.875	EPSD	COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	O15027	SEC16A	P27361	MAPK3	S228	D224N	224	Missense	distal	-4	no	14.235	14.209	EPSD	COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	O15027	SEC16A	P27361	MAPK3	S304	P305L	305	Missense	proximal	1	no	17.175	8.137	EPSD	COSMIC	9.358	Loss
CMGC_MAPK_ERK1_MAPK3_ST	O15027	SEC16A	P27361	MAPK3	S304	S306T	306	Missense	proximal	2	no	17.175	17.164	EPSD	COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	O15027	SEC16A	P27361	MAPK3	S304	N299S	299	Missense	distal	-5	no	17.175	17.215	EPSD	COSMIC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	O15027	SEC16A	P27361	MAPK3	S304	S303F	303	Missense	proximal	-1	no	17.175	16.971	EPSD	COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	O15027	SEC16A	P27361	MAPK3	S346	G353R	353	Missense	distal	7	no	10.009	10.039	EPSD	COSMIC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	O15027	SEC16A	P27361	MAPK3	S346	S351N	351	Missense	distal	5	no	10.009	9.886	EPSD	COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	O15027	SEC16A	P27361	MAPK3	S383	G382D	382	Missense	proximal	-1	no	9.968	9.987	EPSD	COSMIC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	O15027	SEC16A	P27361	MAPK3	S383	P376L	376	Missense	distal	-7	no	9.968	10.075	EPSD	COSMIC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	O15027	SEC16A	P27361	MAPK3	S383	F385L	385	Missense	proximal	2	no	9.968	9.995	EPSD	COSMIC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	O15027	SEC16A	P27361	MAPK3	S383	S383I	383	Missense	central	0	yes	9.968	0.000	EPSD	COSMIC	9.358	Loss
CMGC_MAPK_ERK1_MAPK3_ST	O15027	SEC16A	P27361	MAPK3	S391	G395D	395	Missense	distal	4	no	16.022	16.063	EPSD	COSMIC;GDSC;CCLE	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	O15027	SEC16A	P27361	MAPK3	S391	T397K	397	Missense	distal	6	no	16.022	15.969	EPSD	COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	O15027	SEC16A	P27361	MAPK3	S391	V393I	393	Missense	proximal	2	no	16.022	16.012	EPSD	COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	O15027	SEC16A	P27361	MAPK3	S391	F385L	385	Missense	distal	-6	no	16.022	16.158	EPSD	COSMIC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	O15027	SEC16A	P27361	MAPK3	S403	V402A	402	Missense	proximal	-1	no	9.765	9.715	EPSD	COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	O15027	SEC16A	P27361	MAPK3	S403	T397K	397	Missense	distal	-6	no	9.765	9.775	EPSD	COSMIC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	O15027	SEC16A	P27361	MAPK3	S403	Q404H	404	Missense	proximal	1	no	9.765	9.953	EPSD	COSMIC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	O15027	SEC16A	P27361	MAPK3	S403	E399K	399	Missense	distal	-4	no	9.765	9.705	EPSD	COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	O15027	SEC16A	P27361	MAPK3	S403	V410M	410	Missense	distal	7	no	9.765	9.897	EPSD	COSMIC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	O15027	SEC16A	P27361	MAPK3	T415	P416Q	416	Missense	proximal	1	no	16.637	8.693	EPSD	COSMIC	9.358	Loss
CMGC_MAPK_ERK1_MAPK3_ST	O15027	SEC16A	P27361	MAPK3	T415	S417N	417	Missense	proximal	2	no	16.637	16.620	EPSD	COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	O15027	SEC16A	P27361	MAPK3	T415	V410M	410	Missense	distal	-5	no	16.637	16.595	EPSD	COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	O15027	SEC16A	P27361	MAPK3	S417	P416Q	416	Missense	proximal	-1	no	18.390	18.303	EPSD	COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	O15027	SEC16A	P27361	MAPK3	S417	S417N	417	Missense	central	0	yes	18.390	0.000	EPSD	COSMIC	9.358	Loss
CMGC_MAPK_ERK1_MAPK3_ST	O15027	SEC16A	P27361	MAPK3	S417	V410M	410	Missense	distal	-7	no	18.390	18.446	EPSD	COSMIC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	O15027	SEC16A	P27361	MAPK3	S432	S431N	431	Missense	proximal	-1	no	12.316	12.267	EPSD	COSMIC;CCLE	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	O15027	SEC16A	P27361	MAPK3	S432	E434K	434	Missense	proximal	2	no	12.316	12.309	EPSD	COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	O15027	SEC16A	P27361	MAPK3	S432	P435L	435	Missense	distal	3	no	12.316	12.279	EPSD	COSMIC;CCLE	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	O15027	SEC16A	P27361	MAPK3	S432	P435Q	435	Missense	distal	3	no	12.316	12.289	EPSD	COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	O15027	SEC16A	P27361	MAPK3	S542	A549V	549	Missense	distal	7	no	14.056	14.028	EPSD	COSMIC;CCLE	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	O15027	SEC16A	P27361	MAPK3	S542	E541V	541	Missense	proximal	-1	no	14.056	13.996	EPSD	COSMIC;GDSC;CCLE	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	O15027	SEC16A	P27361	MAPK3	S597	A598V	598	Missense	proximal	1	no	10.748	10.565	EPSD	COSMIC;GDSC;CCLE	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	O15027	SEC16A	P27361	MAPK3	S597	P600L	600	Missense	distal	3	no	10.748	10.712	EPSD	COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	O15027	SEC16A	P27361	MAPK3	S597	A599T	599	Missense	proximal	2	no	10.748	10.776	EPSD	COSMIC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	O15027	SEC16A	P27361	MAPK3	S597	R593W	593	Missense	distal	-4	no	10.748	10.541	EPSD	COSMIC;GDSC;CCLE	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	O15027	SEC16A	P27361	MAPK3	S597	P600Q	600	Missense	distal	3	no	10.748	10.722	EPSD	COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	O15027	SEC16A	P27361	MAPK3	S639	S644F	644	Missense	distal	5	no	15.854	15.429	EPSD	COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	O15027	SEC16A	P27361	MAPK3	S639	P641L	641	Missense	proximal	2	no	15.854	15.832	EPSD	COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	O15027	SEC16A	P27361	MAPK3	S639	P640Q	640	Missense	proximal	1	no	15.854	7.910	EPSD	COSMIC	9.358	Loss
CMGC_MAPK_ERK1_MAPK3_ST	O15027	SEC16A	P27361	MAPK3	S639	G632D	632	Missense	distal	-7	no	15.854	15.859	EPSD	COSMIC;CCLE	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	O15027	SEC16A	P27361	MAPK3	S779	P774L	774	Missense	distal	-5	no	14.828	14.773	EPSD	COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	O15027	SEC16A	P27361	MAPK3	S779	P774S	774	Missense	distal	-5	no	14.828	14.833	EPSD	COSMIC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	O15027	SEC16A	P27361	MAPK3	S779	S783N	783	Missense	distal	4	no	14.828	14.681	EPSD	COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	O15027	SEC16A	P27361	MAPK3	S779	G775R	775	Missense	distal	-4	no	14.828	14.789	EPSD	COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	O15027	SEC16A	P27361	MAPK3	S847	A840D	840	Missense	distal	-7	no	9.555	9.448	EPSD	COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	O15027	SEC16A	P27361	MAPK3	S847	S847N	847	Missense	central	0	yes	9.555	0.000	EPSD	COSMIC	9.358	Loss
CMGC_MAPK_ERK1_MAPK3_ST	O15027	SEC16A	P27361	MAPK3	S847	S852C	852	Missense	distal	5	no	9.555	9.032	EPSD	COSMIC	9.358	Loss
CMGC_MAPK_ERK1_MAPK3_ST	O15027	SEC16A	P27361	MAPK3	S891	P893Q	893	Missense	proximal	2	no	16.934	16.914	EPSD	COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	O15027	SEC16A	P27361	MAPK3	S891	P886F	886	Missense	distal	-5	no	16.934	16.805	EPSD	COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	O15027	SEC16A	P27361	MAPK3	S891	P885S	885	Missense	distal	-6	no	16.934	17.019	EPSD	COSMIC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	O15027	SEC16A	P27361	MAPK3	S1149	D1143Y	1143	Missense	distal	-6	no	9.735	9.543	EPSD	COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	O15027	SEC16A	P27361	MAPK3	S1149	P1154H	1154	Missense	distal	5	no	9.735	9.670	EPSD	COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	O15027	SEC16A	P27361	MAPK3	S1149	Y1142N	1142	Missense	distal	-7	no	9.735	9.684	EPSD	COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	O15027	SEC16A	P27361	MAPK3	S1149	T1147M	1147	Missense	proximal	-2	no	9.735	7.967	EPSD	COSMIC	9.358	Loss
CMGC_MAPK_ERK1_MAPK3_ST	O15027	SEC16A	P27361	MAPK3	S1149	R1145H	1145	Missense	distal	-4	no	9.735	9.749	EPSD	COSMIC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	O15027	SEC16A	P27361	MAPK3	S1184	L1185P	1185	Missense	proximal	1	no	6.183	15.221	EPSD	COSMIC	9.358	Gain
CMGC_MAPK_ERK1_MAPK3_ST	O15027	SEC16A	P27361	MAPK3	S1187	L1185P	1185	Missense	proximal	-2	no	8.032	9.416	EPSD	COSMIC	9.358	Gain
CMGC_MAPK_ERK1_MAPK3_ST	O15027	SEC16A	P27361	MAPK3	S1196	R1189H	1189	Missense	distal	-7	no	9.865	9.854	EPSD	COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	O15027	SEC16A	P27361	MAPK3	S1196	S1191C	1191	Missense	distal	-5	no	9.865	9.703	EPSD	COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	O15027	SEC16A	P27361	MAPK3	S1196	H1197N	1197	Missense	proximal	1	no	9.865	3.533	EPSD	COSMIC	9.358	Loss
CMGC_MAPK_ERK1_MAPK3_ST	O15027	SEC16A	P27361	MAPK3	S1204	A1209S	1209	Missense	distal	5	no	9.170	9.425	EPSD	COSMIC	9.358	Gain
CMGC_MAPK_ERK1_MAPK3_ST	O15027	SEC16A	P27361	MAPK3	S1204	H1205Y	1205	Missense	proximal	1	no	9.170	9.877	EPSD	COSMIC	9.358	Gain
CMGC_MAPK_ERK1_MAPK3_ST	O15027	SEC16A	P27361	MAPK3	S1211	A1209S	1209	Missense	proximal	-2	no	8.724	9.999	EPSD	COSMIC	9.358	Gain
CMGC_MAPK_ERK1_MAPK3_ST	O15027	SEC16A	P27361	MAPK3	S1220	P1218Q	1218	Missense	proximal	-2	no	10.987	9.223	EPSD	COSMIC	9.358	Loss
CMGC_MAPK_ERK1_MAPK3_ST	O15027	SEC16A	P27361	MAPK3	S1220	L1216P	1216	Missense	distal	-4	no	10.987	11.099	EPSD	COSMIC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	O15027	SEC16A	P27361	MAPK3	S1220	H1222Y	1222	Missense	proximal	2	no	10.987	10.980	EPSD	COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	O15027	SEC16A	P27361	MAPK3	S1220	D1224N	1224	Missense	distal	4	no	10.987	10.960	EPSD	COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	O15027	SEC16A	P27361	MAPK3	S1220	P1215L	1215	Missense	distal	-5	no	10.987	10.932	EPSD	COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	O15027	SEC16A	P27361	MAPK3	S1263	F1267I	1267	Missense	distal	4	no	15.153	15.227	EPSD	COSMIC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	O15027	SEC16A	P27361	MAPK3	S1263	R1260I	1260	Missense	distal	-3	no	15.153	15.080	EPSD	COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	O15027	SEC16A	P27361	MAPK3	S1263	S1263F	1263	Missense	central	0	yes	15.153	0.000	EPSD	COSMIC	9.358	Loss
CMGC_MAPK_ERK1_MAPK3_ST	O15027	SEC16A	P27361	MAPK3	S1263	P1270T	1270	Missense	distal	7	no	15.153	15.194	EPSD	COSMIC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	O15027	SEC16A	P27361	MAPK3	S1395	L1391V	1391	Missense	distal	-4	no	15.285	15.274	EPSD	COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	O15027	SEC16A	P27361	MAPK3	S1395	G1393R	1393	Missense	proximal	-2	no	15.285	16.002	EPSD	COSMIC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	O15027	SEC16A	P27361	MAPK3	S1395	W1390C	1390	Missense	distal	-5	no	15.285	15.323	EPSD	COSMIC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	O15027	SEC16A	P27361	MAPK3	S1423	E1419K	1419	Missense	distal	-4	no	9.762	9.702	EPSD	COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	O15027	SEC16A	P27361	MAPK3	S1423	Q1421K	1421	Missense	proximal	-2	no	9.762	9.185	EPSD	COSMIC	9.358	Loss
CMGC_MAPK_ERK1_MAPK3_ST	O15027	SEC16A	P27361	MAPK3	T1551	L1552P	1552	Missense	proximal	1	no	4.915	13.953	EPSD	COSMIC	9.358	Gain
CMGC_MAPK_ERK1_MAPK3_ST	O15027	SEC16A	P27361	MAPK3	S1623	I1630V	1630	Missense	distal	7	no	10.809	10.729	EPSD	COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	O15027	SEC16A	P27361	MAPK3	S1623	S1623C	1623	Missense	central	0	yes	10.809	0.000	EPSD	COSMIC	9.358	Loss
CMGC_MAPK_ERK1_MAPK3_ST	O15027	SEC16A	P27361	MAPK3	S1623	P1622H	1622	Missense	proximal	-1	no	10.809	10.764	EPSD	COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	O15027	SEC16A	P27361	MAPK3	S1663	L1656M	1656	Missense	distal	-7	no	16.551	16.611	EPSD	COSMIC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	O15027	SEC16A	P27361	MAPK3	S1663	P1659L	1659	Missense	distal	-4	no	16.551	16.438	EPSD	COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	O15027	SEC16A	P27361	MAPK3	T1729	P1723S	1723	Missense	distal	-6	no	16.604	16.688	EPSD	COSMIC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	O15027	SEC16A	P27361	MAPK3	T1729	P1727S	1727	Missense	proximal	-2	no	16.604	15.528	EPSD	COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	O15027	SEC16A	P27361	MAPK3	S1761	P1758H	1758	Missense	distal	-3	no	15.333	15.293	EPSD	COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	O15027	SEC16A	P27361	MAPK3	S1761	S1765L	1765	Missense	distal	4	no	15.333	15.130	EPSD	COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	O15027	SEC16A	P27361	MAPK3	S1761	P1767L	1767	Missense	distal	6	no	15.333	15.107	EPSD	COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	O15027	SEC16A	P27361	MAPK3	S1761	A1759T	1759	Missense	proximal	-2	no	15.333	16.698	EPSD	COSMIC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	O15027	SEC16A	P27361	MAPK3	S1766	S1765L	1765	Missense	proximal	-1	no	16.108	16.019	EPSD	COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	O15027	SEC16A	P27361	MAPK3	S1766	P1767L	1767	Missense	proximal	1	no	16.108	7.069	EPSD	COSMIC	9.358	Loss
CMGC_MAPK_ERK1_MAPK3_ST	O15027	SEC16A	P27361	MAPK3	S1766	A1759T	1759	Missense	distal	-7	no	16.108	16.034	EPSD	COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	O15027	SEC16A	P27361	MAPK3	T1810	L1815F	1815	Missense	distal	5	no	13.414	13.261	EPSD	COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	O15027	SEC16A	P27361	MAPK3	S1844	P1851L	1851	Missense	distal	7	no	16.566	16.758	EPSD	COSMIC;GDSC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	O15027	SEC16A	P27361	MAPK3	T1876	K1871Q	1871	Missense	distal	-5	no	13.176	13.169	EPSD	COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	O15027	SEC16A	P27361	MAPK3	T1876	T1880M	1880	Missense	distal	4	no	13.176	12.910	EPSD	COSMIC;GDSC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	O15027	SEC16A	P27361	MAPK3	T1876	S1878L	1878	Missense	proximal	2	no	13.176	13.152	EPSD	COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	O15027	SEC16A	P27361	MAPK3	T1876	P1877H	1877	Missense	proximal	1	no	13.176	5.420	EPSD	COSMIC	9.358	Loss
CMGC_MAPK_ERK1_MAPK3_ST	O15027	SEC16A	P27361	MAPK3	S1905	E1909K	1909	Missense	distal	4	no	18.669	18.631	EPSD	COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	O15027	SEC16A	P27361	MAPK3	S1905	K1911E	1911	Missense	distal	6	no	18.669	18.745	EPSD	COSMIC;GDSC;CCLE	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	O15027	SEC16A	P27361	MAPK3	T1980	P1975S	1975	Missense	distal	-5	no	9.506	9.511	EPSD	COSMIC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	O15027	SEC16A	P27361	MAPK3	T1980	P1975L	1975	Missense	distal	-5	no	9.506	9.451	EPSD	COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	O15027	SEC16A	P27361	MAPK3	T1980	P1983S	1983	Missense	distal	3	no	9.506	9.501	EPSD	COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	O15027	SEC16A	P27361	MAPK3	T1980	P1978S	1978	Missense	proximal	-2	no	9.506	8.430	EPSD	COSMIC;CCLE	9.358	Loss
CMGC_MAPK_ERK1_MAPK3_ST	O15027	SEC16A	P27361	MAPK3	T2053	P2046L	2046	Missense	distal	-7	no	13.944	14.052	EPSD	COSMIC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	O15027	SEC16A	P27361	MAPK3	T2053	P2059S	2059	Missense	distal	6	no	13.944	14.074	EPSD	COSMIC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	O15027	SEC16A	P27361	MAPK3	T2053	T2053I	2053	Missense	central	0	yes	13.944	0.000	EPSD	COSMIC;GDSC;CCLE	9.358	Loss
CMGC_MAPK_ERK1_MAPK3_ST	O15027	SEC16A	P27361	MAPK3	T2053	N2048D	2048	Missense	distal	-5	no	13.944	13.950	EPSD	COSMIC;GDSC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q9NRA0	SPHK2	P27361	MAPK3	S107	T102P	102	Missense	distal	-5	no	15.947	15.958	EPSD	COSMIC;GDSC;CCLE	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q9NRA0	SPHK2	P27361	MAPK3	S107	S105N	105	Missense	proximal	-2	no	15.947	15.003	EPSD	COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q9NRA0	SPHK2	P27361	MAPK3	S107	R104W	104	Missense	distal	-3	no	15.947	15.780	EPSD	COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q9NRA0	SPHK2	P27361	MAPK3	S107	R104Q	104	Missense	distal	-3	no	15.947	15.940	EPSD	COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q9NRA0	SPHK2	P27361	MAPK3	S107	A112V	112	Missense	distal	5	no	15.947	15.936	EPSD	COSMIC;GDSC;CCLE	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q9NRA0	SPHK2	P27361	MAPK3	S387	P380L	380	Missense	distal	-7	no	18.067	18.174	PhosphoSitePlus;EPSD	COSMIC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q9NRA0	SPHK2	P27361	MAPK3	S387	P380H	380	Missense	distal	-7	no	18.067	18.101	PhosphoSitePlus;EPSD	COSMIC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q9NRA0	SPHK2	P27361	MAPK3	T389	R396H	396	Missense	distal	7	no	15.007	14.974	EPSD	COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q9NRA0	SPHK2	P27361	MAPK3	T404	S399L	399	Missense	distal	-5	no	15.509	15.449	EPSD	COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q9NRA0	SPHK2	P27361	MAPK3	T404	P407Q	407	Missense	distal	3	no	15.509	15.482	EPSD	COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q9NRA0	SPHK2	P27361	MAPK3	T404	D406G	406	Missense	proximal	2	no	15.509	15.504	EPSD	COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q9NRA0	SPHK2	P27361	MAPK3	T404	A397T	397	Missense	distal	-7	no	15.509	15.436	EPSD	COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q9NRA0	SPHK2	P27361	MAPK3	T404	P405Q	405	Missense	proximal	1	no	15.509	7.565	EPSD	COSMIC	9.358	Loss
CMGC_MAPK_ERK1_MAPK3_ST	Q9NRA0	SPHK2	P27361	MAPK3	T404	P405L	405	Missense	proximal	1	no	15.509	6.471	EPSD	COSMIC	9.358	Loss
CMGC_MAPK_ERK1_MAPK3_ST	Q9NRA0	SPHK2	P27361	MAPK3	T404	P405S	405	Missense	proximal	1	no	15.509	6.456	EPSD	COSMIC	9.358	Loss
CMGC_MAPK_ERK1_MAPK3_ST	Q9NRA0	SPHK2	P27361	MAPK3	S414	S419F	419	Missense	distal	5	no	15.285	14.860	EPSD	COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q9NRA0	SPHK2	P27361	MAPK3	S414	H417N	417	Missense	distal	3	no	15.285	15.278	EPSD	COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q9NRA0	SPHK2	P27361	MAPK3	S414	R418C	418	Missense	distal	4	no	15.285	14.928	EPSD	COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q9NRA0	SPHK2	P27361	MAPK3	S414	P407Q	407	Missense	distal	-7	no	15.285	15.329	EPSD	COSMIC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q9NRA0	SPHK2	P27361	MAPK3	S473	P469L	469	Missense	distal	-4	no	16.344	16.231	EPSD	COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q9NRA0	SPHK2	P27361	MAPK3	S484	E488K	488	Missense	distal	4	no	17.628	17.589	EPSD	COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q9NRA0	SPHK2	P27361	MAPK3	T503	S496P	496	Missense	distal	-7	no	14.766	14.804	EPSD	COSMIC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q9NRA0	SPHK2	P27361	MAPK3	T503	R507Q	507	Missense	distal	4	no	14.766	14.722	EPSD	COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q9NRA0	SPHK2	P27361	MAPK3	T614	G617S	617	Missense	distal	3	no	17.419	17.434	EPSD;PhosphoSitePlus	COSMIC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q9NRA0	SPHK2	P27361	MAPK3	T614	T620A	620	Missense	distal	6	no	17.419	17.048	EPSD;PhosphoSitePlus	COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P05412	JUN	P27361	MAPK3	S63	K56N	56	Missense	distal	-7	no	15.849	15.833	EPSD;PhosphoSitePlus	COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P05412	JUN	P27361	MAPK3	S63	L61F	61	Missense	proximal	-2	no	15.849	14.857	EPSD;PhosphoSitePlus	COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P05412	JUN	P27361	MAPK3	S73	R78H	78	Missense	distal	5	no	16.312	16.348	PhosphoSitePlus;EPSD	COSMIC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P05412	JUN	P27361	MAPK3	T91	P92Q	92	Missense	proximal	1	no	15.046	7.102	EPSD	COSMIC	9.358	Loss
CMGC_MAPK_ERK1_MAPK3_ST	P05412	JUN	P27361	MAPK3	T91	L98M	98	Missense	distal	7	no	15.046	15.227	EPSD	COSMIC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P05412	JUN	P27361	MAPK3	T91	P94S	94	Missense	distal	3	no	15.046	15.042	EPSD	COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P05412	JUN	P27361	MAPK3	T93	P100L	100	Missense	distal	7	no	12.688	12.880	EPSD	COSMIC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P05412	JUN	P27361	MAPK3	T93	P92Q	92	Missense	proximal	-1	no	12.688	12.601	EPSD	COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P05412	JUN	P27361	MAPK3	T93	L98M	98	Missense	distal	5	no	12.688	12.568	EPSD	COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P05412	JUN	P27361	MAPK3	T93	P94S	94	Missense	proximal	1	no	12.688	3.634	EPSD	COSMIC	9.358	Loss
CMGC_MAPK_ERK1_MAPK3_ST	P05412	JUN	P27361	MAPK3	T239	P240Q	240	Missense	proximal	1	no	15.173	7.229	EPSD	COSMIC	9.358	Loss
CMGC_MAPK_ERK1_MAPK3_ST	P05412	JUN	P27361	MAPK3	T239	T239I	239	Missense	central	0	yes	15.173	0.000	EPSD	COSMIC	9.358	Loss
CMGC_MAPK_ERK1_MAPK3_ST	P05412	JUN	P27361	MAPK3	S243	P240Q	240	Missense	distal	-3	no	18.294	18.240	EPSD	COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P05412	JUN	P27361	MAPK3	S243	T239I	239	Missense	distal	-4	no	18.294	18.193	EPSD	COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q03060	CREM	P27361	MAPK3	S24	S29L	29	Missense	distal	5	no	11.372	11.101	EPSD	COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q03060	CREM	P27361	MAPK3	S24	T18N	18	Missense	distal	-6	no	11.372	11.418	EPSD	COSMIC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q03060	CREM	P27361	MAPK3	S24	T21A	21	Missense	distal	-3	no	11.372	11.310	EPSD	COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q03060	CREM	P27361	MAPK3	S24	D27G	27	Missense	distal	3	no	11.372	11.367	EPSD	COSMIC;GDSC;CCLE	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q03060	CREM	P27361	MAPK3	S24	G28S	28	Missense	distal	4	no	11.372	11.533	EPSD	COSMIC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q03060	CREM	P27361	MAPK3	S24	G28C	28	Missense	distal	4	no	11.372	11.029	EPSD	COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q03060	CREM	P27361	MAPK3	S287	L291P	291	Missense	distal	4	no	14.982	15.136	EPSD	COSMIC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q03060	CREM	P27361	MAPK3	S290	L291P	291	Missense	proximal	1	no	9.745	18.783	EPSD	COSMIC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q03060	CREM	P27361	MAPK3	S293	E300K	300	Missense	distal	7	no	14.622	14.693	EPSD	COSMIC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q03060	CREM	P27361	MAPK3	S293	L291P	291	Missense	proximal	-2	no	14.622	16.007	EPSD	COSMIC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q02750	MAP2K1	P27361	MAPK3	T23	S24Y	24	Missense	proximal	1	no	7.913	9.918	EPSD	COSMIC	9.358	Gain
CMGC_MAPK_ERK1_MAPK3_ST	Q02750	MAP2K1	P27361	MAPK3	S24	E27K	27	Missense	distal	3	no	9.481	9.471	EPSD	COSMIC;CCLE	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q02750	MAP2K1	P27361	MAPK3	S24	S24Y	24	Missense	central	0	yes	9.481	0.000	EPSD	COSMIC	9.358	Loss
CMGC_MAPK_ERK1_MAPK3_ST	Q02750	MAP2K1	P27361	MAPK3	S24	E27V	27	Missense	distal	3	no	9.481	9.457	EPSD	COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q02750	MAP2K1	P27361	MAPK3	S24	G22V	22	Missense	proximal	-2	no	9.481	9.944	EPSD	COSMIC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q02750	MAP2K1	P27361	MAPK3	S24	S18A	18	Missense	distal	-6	no	9.481	9.165	EPSD	COSMIC	9.358	Loss
CMGC_MAPK_ERK1_MAPK3_ST	Q02750	MAP2K1	P27361	MAPK3	S24	L30F	30	Missense	distal	6	no	9.481	9.124	EPSD	COSMIC	9.358	Loss
CMGC_MAPK_ERK1_MAPK3_ST	Q02750	MAP2K1	P27361	MAPK3	S25	E27K	27	Missense	proximal	2	no	11.000	10.993	EPSD	COSMIC;CCLE	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q02750	MAP2K1	P27361	MAPK3	S25	S24Y	24	Missense	proximal	-1	no	11.000	10.924	EPSD	COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q02750	MAP2K1	P27361	MAPK3	S25	E27V	27	Missense	proximal	2	no	11.000	10.984	EPSD	COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q02750	MAP2K1	P27361	MAPK3	S25	G22V	22	Missense	distal	-3	no	11.000	10.961	EPSD	COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q02750	MAP2K1	P27361	MAPK3	S25	S18A	18	Missense	distal	-7	no	11.000	11.150	EPSD	COSMIC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q02750	MAP2K1	P27361	MAPK3	S25	L30F	30	Missense	distal	5	no	11.000	10.847	EPSD	COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q02750	MAP2K1	P27361	MAPK3	S222	L215F	215	Missense	distal	-7	no	9.353	9.427	EPSD	COSMIC	9.358	Gain
CMGC_MAPK_ERK1_MAPK3_ST	Q02750	MAP2K1	P27361	MAPK3	S231	Y229H	229	Missense	proximal	-2	no	17.940	18.022	EPSD	COSMIC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q02750	MAP2K1	P27361	MAPK3	T286	A283V	283	Missense	distal	-3	no	14.936	14.955	PhosphoSitePlus;EPSD	COSMIC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q02750	MAP2K1	P27361	MAPK3	T286	P293S	293	Missense	distal	7	no	14.936	14.859	PhosphoSitePlus;EPSD	COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q02750	MAP2K1	P27361	MAPK3	T286	R291K	291	Missense	distal	5	no	14.936	14.928	PhosphoSitePlus;EPSD	COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q02750	MAP2K1	P27361	MAPK3	T292	P293S	293	Missense	proximal	1	no	16.441	7.388	EPSD;PhosphoSitePlus	COSMIC	9.358	Loss
CMGC_MAPK_ERK1_MAPK3_ST	Q02750	MAP2K1	P27361	MAPK3	T292	R291K	291	Missense	proximal	-1	no	16.441	16.428	EPSD;PhosphoSitePlus	COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q02750	MAP2K1	P27361	MAPK3	S299	P306H	306	Missense	distal	7	no	9.721	9.781	EPSD	COSMIC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q02750	MAP2K1	P27361	MAPK3	S299	G301E	301	Missense	proximal	2	no	9.721	9.729	EPSD	COSMIC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q02750	MAP2K1	P27361	MAPK3	S299	P293S	293	Missense	distal	-6	no	9.721	9.806	EPSD	COSMIC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q02750	MAP2K1	P27361	MAPK3	S377	L375P	375	Missense	proximal	-2	no	9.215	10.599	EPSD	COSMIC	9.358	Gain
CMGC_MAPK_ERK1_MAPK3_ST	Q02750	MAP2K1	P27361	MAPK3	S385	P387S	387	Missense	proximal	2	no	9.803	9.804	EPSD	COSMIC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q02750	MAP2K1	P27361	MAPK3	S385	A390T	390	Missense	distal	5	no	9.803	9.922	EPSD	COSMIC;GDSC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q02750	MAP2K1	P27361	MAPK3	S385	N382H	382	Missense	distal	-3	no	9.803	9.815	EPSD	COSMIC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q02750	MAP2K1	P27361	MAPK3	T386	P387S	387	Missense	proximal	1	no	20.053	11.000	EPSD	COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q02750	MAP2K1	P27361	MAPK3	T386	A390T	390	Missense	distal	4	no	20.053	20.271	EPSD	COSMIC;GDSC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q02750	MAP2K1	P27361	MAPK3	T386	N382H	382	Missense	distal	-4	no	20.053	20.051	EPSD	COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q02750	MAP2K1	P27361	MAPK3	T388	P387S	387	Missense	proximal	-1	no	10.530	10.524	EPSD	COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q02750	MAP2K1	P27361	MAPK3	T388	A390T	390	Missense	proximal	2	no	10.530	10.557	EPSD	COSMIC;GDSC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q02750	MAP2K1	P27361	MAPK3	T388	N382H	382	Missense	distal	-6	no	10.530	10.488	EPSD	COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q00613	HSF1	P27361	MAPK3	S244	S237L	237	Missense	distal	-7	no	15.761	15.906	EPSD	COSMIC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q00613	HSF1	P27361	MAPK3	S244	P239H	239	Missense	distal	-5	no	15.761	15.730	EPSD	COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q00613	HSF1	P27361	MAPK3	S244	S244F	244	Missense	central	0	yes	15.761	0.000	EPSD	COSMIC	9.358	Loss
CMGC_MAPK_ERK1_MAPK3_ST	Q00613	HSF1	P27361	MAPK3	S275	S279F	279	Missense	distal	4	no	17.431	17.016	EPSD	COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q00613	HSF1	P27361	MAPK3	S275	P280L	280	Missense	distal	5	no	17.431	17.203	EPSD	COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q00613	HSF1	P27361	MAPK3	S275	I268V	268	Missense	distal	-7	no	17.431	17.388	EPSD	COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q00613	HSF1	P27361	MAPK3	S275	G281S	281	Missense	distal	6	no	17.431	17.663	EPSD	COSMIC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q00613	HSF1	P27361	MAPK3	S279	S279F	279	Missense	central	0	yes	14.389	0.000	EPSD	COSMIC	9.358	Loss
CMGC_MAPK_ERK1_MAPK3_ST	Q00613	HSF1	P27361	MAPK3	S279	P280L	280	Missense	proximal	1	no	14.389	5.351	EPSD	COSMIC	9.358	Loss
CMGC_MAPK_ERK1_MAPK3_ST	Q00613	HSF1	P27361	MAPK3	S279	G281S	281	Missense	proximal	2	no	14.389	14.406	EPSD	COSMIC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q00613	HSF1	P27361	MAPK3	S279	S283N	283	Missense	distal	4	no	14.389	14.243	EPSD	COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q00613	HSF1	P27361	MAPK3	S303	S303G	303	Missense	central	0	yes	17.854	0.000	EPSD	COSMIC	9.358	Loss
CMGC_MAPK_ERK1_MAPK3_ST	Q00613	HSF1	P27361	MAPK3	S303	P304L	304	Missense	proximal	1	no	17.854	8.816	EPSD	COSMIC;GDSC	9.358	Loss
CMGC_MAPK_ERK1_MAPK3_ST	Q00613	HSF1	P27361	MAPK3	S303	R309G	309	Missense	distal	6	no	17.854	17.863	EPSD	COSMIC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q00613	HSF1	P27361	MAPK3	S307	S303G	303	Missense	distal	-4	no	16.210	16.172	PhosphoSitePlus;EPSD	COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q00613	HSF1	P27361	MAPK3	S307	P304L	304	Missense	distal	-3	no	16.210	16.126	PhosphoSitePlus;EPSD	COSMIC;GDSC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q00613	HSF1	P27361	MAPK3	S307	R309G	309	Missense	proximal	2	no	16.210	16.206	PhosphoSitePlus;EPSD	COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q00613	HSF1	P27361	MAPK3	S314	R309G	309	Missense	distal	-5	no	17.255	17.257	EPSD	COSMIC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q00613	HSF1	P27361	MAPK3	S314	P318T	318	Missense	distal	4	no	17.255	17.191	EPSD	COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q00613	HSF1	P27361	MAPK3	S326	L330V	330	Missense	distal	4	no	15.827	15.807	EPSD;PhosphoSitePlus	COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q00613	HSF1	P27361	MAPK3	S326	P327Q	327	Missense	proximal	1	no	15.827	7.883	EPSD;PhosphoSitePlus	COSMIC	9.358	Loss
CMGC_MAPK_ERK1_MAPK3_ST	Q00613	HSF1	P27361	MAPK3	S363	S363P	363	Missense	central	0	yes	17.748	0.000	EPSD	COSMIC	9.358	Loss
CMGC_MAPK_ERK1_MAPK3_ST	Q00613	HSF1	P27361	MAPK3	S363	P365Q	365	Missense	proximal	2	no	17.748	17.728	EPSD	COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q00613	HSF1	P27361	MAPK3	S363	D356N	356	Missense	distal	-7	no	17.748	17.773	EPSD	COSMIC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q00613	HSF1	P27361	MAPK3	S363	P365T	365	Missense	proximal	2	no	17.748	17.739	EPSD	COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q00613	HSF1	P27361	MAPK3	S363	E358K	358	Missense	distal	-5	no	17.748	17.736	EPSD	COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q00613	HSF1	P27361	MAPK3	S363	P365L	365	Missense	proximal	2	no	17.748	17.726	EPSD	COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q00613	HSF1	P27361	MAPK3	T369	S363P	363	Missense	distal	-6	no	15.694	15.609	EPSD	COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q00613	HSF1	P27361	MAPK3	T369	P365Q	365	Missense	distal	-4	no	15.694	15.654	EPSD	COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q00613	HSF1	P27361	MAPK3	T369	P365T	365	Missense	distal	-4	no	15.694	15.663	EPSD	COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q00613	HSF1	P27361	MAPK3	T369	L374F	374	Missense	distal	5	no	15.694	15.540	EPSD	COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q00613	HSF1	P27361	MAPK3	T369	P365L	365	Missense	distal	-4	no	15.694	15.581	EPSD	COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q00613	HSF1	P27361	MAPK3	S419	L417Q	417	Missense	proximal	-2	no	15.478	15.098	EPSD	COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q00613	HSF1	P27361	MAPK3	S419	V422M	422	Missense	distal	3	no	15.478	15.453	EPSD	COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q00613	HSF1	P27361	MAPK3	S419	S419N	419	Missense	central	0	yes	15.478	0.000	EPSD	COSMIC	9.358	Loss
CMGC_MAPK_ERK1_MAPK3_ST	Q00613	HSF1	P27361	MAPK3	S444	E447K	447	Missense	distal	3	no	18.515	18.504	EPSD	COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q00613	HSF1	P27361	MAPK3	S458	P452H	452	Missense	distal	-6	no	15.842	15.762	EPSD	COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q00613	HSF1	P27361	MAPK3	S513	E519K	519	Missense	distal	6	no	9.594	9.517	EPSD	COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q00613	HSF1	P27361	MAPK3	S518	E519K	519	Missense	proximal	1	no	10.477	2.572	EPSD	COSMIC	9.358	Loss
CMGC_MAPK_ERK1_MAPK3_ST	Q9UIG0	BAZ1B	P27361	MAPK3	S197	T203S	203	Missense	distal	6	no	17.898	18.052	EPSD	COSMIC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q9UIG0	BAZ1B	P27361	MAPK3	S204	L205F	205	Missense	proximal	1	no	8.969	11.794	EPSD	COSMIC	9.358	Gain
CMGC_MAPK_ERK1_MAPK3_ST	Q9UIG0	BAZ1B	P27361	MAPK3	S349	S347G	347	Missense	proximal	-2	no	14.444	13.404	EPSD	COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q9UIG0	BAZ1B	P27361	MAPK3	S361	P362L	362	Missense	proximal	1	no	16.637	7.599	EPSD	COSMIC	9.358	Loss
CMGC_MAPK_ERK1_MAPK3_ST	Q9UIG0	BAZ1B	P27361	MAPK3	S423	L428M	428	Missense	distal	5	no	16.421	16.301	EPSD	COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q9UIG0	BAZ1B	P27361	MAPK3	T430	K432Q	432	Missense	proximal	2	no	15.578	15.572	EPSD	COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q9UIG0	BAZ1B	P27361	MAPK3	T430	L428M	428	Missense	proximal	-2	no	15.578	14.208	EPSD	COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q9UIG0	BAZ1B	P27361	MAPK3	T430	K432I	432	Missense	proximal	2	no	15.578	15.559	EPSD	COSMIC;GDSC;CCLE	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q9UIG0	BAZ1B	P27361	MAPK3	T460	P461S	461	Missense	proximal	1	no	14.590	5.537	EPSD	COSMIC	9.358	Loss
CMGC_MAPK_ERK1_MAPK3_ST	Q9UIG0	BAZ1B	P27361	MAPK3	T460	R455W	455	Missense	distal	-5	no	14.590	14.436	EPSD	COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q9ULV5	HSF4	P27361	MAPK3	T221	S217R	217	Missense	distal	-4	no	13.799	13.722	EPSD	COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	C9JLW8	MCRIP1	P27361	MAPK3	S4	P5S	5	Missense	proximal	1	no	15.252	6.198	EPSD	COSMIC	9.358	Loss
CMGC_MAPK_ERK1_MAPK3_ST	C9JLW8	MCRIP1	P27361	MAPK3	S17	N12K	12	Missense	distal	-5	no	11.407	11.401	EPSD	COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	C9JLW8	MCRIP1	P27361	MAPK3	S17	T16K	16	Missense	proximal	-1	no	11.407	11.382	EPSD	COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	C9JLW8	MCRIP1	P27361	MAPK3	S18	N12K	12	Missense	distal	-6	no	19.364	19.328	EPSD	COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	C9JLW8	MCRIP1	P27361	MAPK3	S18	T16K	16	Missense	proximal	-2	no	19.364	18.009	EPSD	COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	C9JLW8	MCRIP1	P27361	MAPK3	S21	T16K	16	Missense	distal	-5	no	19.985	19.954	PhosphoSitePlus;EPSD	COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	C9JLW8	MCRIP1	P27361	MAPK3	T30	V37I	37	Missense	distal	7	no	15.497	15.578	EPSD;PhosphoSitePlus	COSMIC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	C9JLW8	MCRIP1	P27361	MAPK3	S74	K79R	79	Missense	distal	5	no	9.842	9.851	EPSD	COSMIC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	C9JLW8	MCRIP1	P27361	MAPK3	S74	I81V	81	Missense	distal	7	no	9.842	9.762	EPSD	COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	C9JLW8	MCRIP1	P27361	MAPK3	S84	K79R	79	Missense	distal	-5	no	9.736	9.737	EPSD	COSMIC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	C9JLW8	MCRIP1	P27361	MAPK3	S84	R88C	88	Missense	distal	4	no	9.736	9.379	EPSD	COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	C9JLW8	MCRIP1	P27361	MAPK3	S84	I81V	81	Missense	distal	-3	no	9.736	9.775	EPSD	COSMIC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q8N122	RPTOR	P27361	MAPK3	S8	S3Y	3	Missense	distal	-5	no	16.132	16.068	EPSD;PhosphoSitePlus	COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q8N122	RPTOR	P27361	MAPK3	S696	E689K	689	Missense	distal	-7	no	16.759	16.810	PhosphoSitePlus;EPSD	COSMIC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q8N122	RPTOR	P27361	MAPK3	S696	S696Y	696	Missense	central	0	yes	16.759	0.000	PhosphoSitePlus;EPSD	COSMIC	9.358	Loss
CMGC_MAPK_ERK1_MAPK3_ST	Q8N122	RPTOR	P27361	MAPK3	S696	A693T	693	Missense	distal	-3	no	16.759	16.820	PhosphoSitePlus;EPSD	COSMIC;GDSC;CCLE	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q8N122	RPTOR	P27361	MAPK3	S696	G702E	702	Missense	distal	6	no	16.759	16.860	PhosphoSitePlus;EPSD	COSMIC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q8N122	RPTOR	P27361	MAPK3	S696	S696A	696	Missense	central	0	yes	16.759	0.000	PhosphoSitePlus;EPSD	COSMIC	9.358	Loss
CMGC_MAPK_ERK1_MAPK3_ST	Q8N122	RPTOR	P27361	MAPK3	T706	P712L	712	Missense	distal	6	no	16.131	15.905	EPSD	COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q8N122	RPTOR	P27361	MAPK3	T706	D710N	710	Missense	distal	4	no	16.131	16.104	EPSD	COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q8N122	RPTOR	P27361	MAPK3	T706	R709G	709	Missense	distal	3	no	16.131	16.138	EPSD	COSMIC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q8N122	RPTOR	P27361	MAPK3	T706	G702E	702	Missense	distal	-4	no	16.131	16.146	EPSD	COSMIC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q8N122	RPTOR	P27361	MAPK3	S711	R718C	718	Missense	distal	7	no	17.781	18.224	EPSD	COSMIC;CCLE	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q8N122	RPTOR	P27361	MAPK3	S711	P712L	712	Missense	proximal	1	no	17.781	8.743	EPSD	COSMIC	9.358	Loss
CMGC_MAPK_ERK1_MAPK3_ST	Q8N122	RPTOR	P27361	MAPK3	S711	P715S	715	Missense	distal	4	no	17.781	17.830	EPSD	COSMIC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q8N122	RPTOR	P27361	MAPK3	S711	D710N	710	Missense	proximal	-1	no	17.781	17.779	EPSD	COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q8N122	RPTOR	P27361	MAPK3	S711	R709G	709	Missense	proximal	-2	no	17.781	17.065	EPSD	COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q8N122	RPTOR	P27361	MAPK3	T714	R718C	718	Missense	distal	4	no	15.978	15.621	EPSD	COSMIC;CCLE	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q8N122	RPTOR	P27361	MAPK3	T714	P712L	712	Missense	proximal	-2	no	15.978	14.593	EPSD	COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q8N122	RPTOR	P27361	MAPK3	T714	P715S	715	Missense	proximal	1	no	15.978	6.924	EPSD	COSMIC	9.358	Loss
CMGC_MAPK_ERK1_MAPK3_ST	Q8N122	RPTOR	P27361	MAPK3	T714	D710N	710	Missense	distal	-4	no	15.978	15.952	EPSD	COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q8N122	RPTOR	P27361	MAPK3	T714	S719Y	719	Missense	distal	5	no	15.978	15.761	EPSD	COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q8N122	RPTOR	P27361	MAPK3	T714	S721N	721	Missense	distal	7	no	15.978	16.143	EPSD	COSMIC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q8N122	RPTOR	P27361	MAPK3	T714	V720L	720	Missense	distal	6	no	15.978	16.059	EPSD	COSMIC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q8N122	RPTOR	P27361	MAPK3	T714	R709G	709	Missense	distal	-5	no	15.978	15.980	EPSD	COSMIC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q8N122	RPTOR	P27361	MAPK3	S771	A765T	765	Missense	distal	-6	no	18.362	18.510	EPSD	COSMIC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q8N122	RPTOR	P27361	MAPK3	S771	E775Q	775	Missense	distal	4	no	18.362	18.271	EPSD	COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q8N122	RPTOR	P27361	MAPK3	S771	S766T	766	Missense	distal	-5	no	18.362	18.347	EPSD	COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q8N122	RPTOR	P27361	MAPK3	S792	A790S	790	Missense	proximal	-2	no	8.446	9.721	EPSD	COSMIC	9.358	Gain
CMGC_MAPK_ERK1_MAPK3_ST	Q8N122	RPTOR	P27361	MAPK3	S803	T809I	809	Missense	distal	6	no	10.000	9.585	EPSD	COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q8N122	RPTOR	P27361	MAPK3	S803	L796I	796	Missense	distal	-7	no	10.000	10.047	EPSD	COSMIC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q8N122	RPTOR	P27361	MAPK3	S803	S798F	798	Missense	distal	-5	no	10.000	9.866	EPSD	COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q8N122	RPTOR	P27361	MAPK3	S803	L799H	799	Missense	distal	-4	no	10.000	10.077	EPSD	COSMIC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q8N122	RPTOR	P27361	MAPK3	S803	Y808C	808	Missense	distal	5	no	10.000	9.693	EPSD	COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q8N122	RPTOR	P27361	MAPK3	S863	K867R	867	Missense	distal	4	no	17.807	17.799	EPSD;PhosphoSitePlus	COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q8N122	RPTOR	P27361	MAPK3	S863	G868S	868	Missense	distal	5	no	17.807	17.872	EPSD;PhosphoSitePlus	COSMIC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q8N122	RPTOR	P27361	MAPK3	S863	P861L	861	Missense	proximal	-2	no	17.807	16.423	EPSD;PhosphoSitePlus	COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q8N122	RPTOR	P27361	MAPK3	S863	V869M	869	Missense	distal	6	no	17.807	17.597	EPSD;PhosphoSitePlus	COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q8N122	RPTOR	P27361	MAPK3	S863	A862T	862	Missense	proximal	-1	no	17.807	17.911	EPSD;PhosphoSitePlus	COSMIC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q8N122	RPTOR	P27361	MAPK3	S877	A874V	874	Missense	distal	-3	no	16.346	16.365	EPSD	COSMIC;GDSC;CCLE	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q8N122	RPTOR	P27361	MAPK3	S877	P878S	878	Missense	proximal	1	no	16.346	7.293	EPSD	COSMIC	9.358	Loss
CMGC_MAPK_ERK1_MAPK3_ST	Q8N122	RPTOR	P27361	MAPK3	S877	P879S	879	Missense	proximal	2	no	16.346	16.348	EPSD	COSMIC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q8N122	RPTOR	P27361	MAPK3	S877	A880S	880	Missense	distal	3	no	16.346	16.390	EPSD	COSMIC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q8N122	RPTOR	P27361	MAPK3	S877	P878L	878	Missense	proximal	1	no	16.346	7.308	EPSD	COSMIC	9.358	Loss
CMGC_MAPK_ERK1_MAPK3_ST	Q8N122	RPTOR	P27361	MAPK3	S881	A874V	874	Missense	distal	-7	no	9.382	9.381	EPSD	COSMIC;GDSC;CCLE	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q8N122	RPTOR	P27361	MAPK3	S881	P878S	878	Missense	distal	-3	no	9.382	9.373	EPSD	COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q8N122	RPTOR	P27361	MAPK3	S881	P879S	879	Missense	proximal	-2	no	9.382	8.306	EPSD	COSMIC	9.358	Loss
CMGC_MAPK_ERK1_MAPK3_ST	Q8N122	RPTOR	P27361	MAPK3	S881	A880S	880	Missense	proximal	-1	no	9.382	9.516	EPSD	COSMIC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q8N122	RPTOR	P27361	MAPK3	S881	P878L	878	Missense	distal	-3	no	9.382	9.298	EPSD	COSMIC	9.358	Loss
CMGC_MAPK_ERK1_MAPK3_ST	Q8N122	RPTOR	P27361	MAPK3	S898	R905W	905	Missense	distal	7	no	8.814	9.390	EPSD	COSMIC	9.358	Gain
CMGC_MAPK_ERK1_MAPK3_ST	Q8N122	RPTOR	P27361	MAPK3	T917	P924T	924	Missense	distal	7	no	14.001	14.042	EPSD	COSMIC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q8N122	RPTOR	P27361	MAPK3	T917	Y916C	916	Missense	proximal	-1	no	14.001	13.851	EPSD	COSMIC;GDSC;CCLE	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q8N122	RPTOR	P27361	MAPK3	T917	P911L	911	Missense	distal	-6	no	14.001	13.754	EPSD	COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q8N122	RPTOR	P27361	MAPK3	T917	G910D	910	Missense	distal	-7	no	14.001	14.006	EPSD	COSMIC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q8N122	RPTOR	P27361	MAPK3	T917	Q922R	922	Missense	distal	5	no	14.001	14.002	EPSD	COSMIC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q8N122	RPTOR	P27361	MAPK3	S920	P924T	924	Missense	distal	4	no	10.601	10.537	EPSD	COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q8N122	RPTOR	P27361	MAPK3	S920	R925W	925	Missense	distal	5	no	10.601	10.133	EPSD	COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q8N122	RPTOR	P27361	MAPK3	S920	Y916C	916	Missense	distal	-4	no	10.601	10.466	EPSD	COSMIC;GDSC;CCLE	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q8N122	RPTOR	P27361	MAPK3	S920	R925Q	925	Missense	distal	5	no	10.601	10.600	EPSD	COSMIC;CCLE	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q8N122	RPTOR	P27361	MAPK3	S920	R927Q	927	Missense	distal	7	no	10.601	10.631	EPSD	COSMIC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q8N122	RPTOR	P27361	MAPK3	S920	R927W	927	Missense	distal	7	no	10.601	11.178	EPSD	COSMIC;CCLE	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q8N122	RPTOR	P27361	MAPK3	S920	Q922R	922	Missense	proximal	2	no	10.601	10.611	EPSD	COSMIC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P49407	ARRB1	P27361	MAPK3	S86	P88S	88	Missense	proximal	2	no	10.307	10.308	EPSD	COSMIC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P49407	ARRB1	P27361	MAPK3	S412	G411S	411	Missense	proximal	-1	no	19.354	19.420	PhosphoSitePlus	COSMIC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P27361	MAPK3	P27361	MAPK3	S263	I257V	257	Missense	distal	-6	no	18.959	19.028	EPSD	COSMIC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P27361	MAPK3	P27361	MAPK3	S263	I260H	260	Missense	distal	-3	no	18.959	19.039	EPSD	COSMIC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P31645	SLC6A4	P27361	MAPK3	S52	Y47C	47	Missense	distal	-5	no	17.221	17.123	EPSD	COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P31645	SLC6A4	P27361	MAPK3	S52	G56E	56	Missense	distal	4	no	17.221	17.282	EPSD	COSMIC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P31645	SLC6A4	P27361	MAPK3	T616	G623R	623	Missense	distal	7	no	19.810	19.840	PhosphoSitePlus	COSMIC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P33076	CIITA	P27361	MAPK3	S280	G276D	276	Missense	distal	-4	no	19.345	19.348	PhosphoSitePlus;EPSD	COSMIC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P33076	CIITA	P27361	MAPK3	S280	G276V	276	Missense	distal	-4	no	19.345	19.231	PhosphoSitePlus;EPSD	COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P33076	CIITA	P27361	MAPK3	S280	P281L	281	Missense	proximal	1	no	19.345	10.307	PhosphoSitePlus;EPSD	COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P33076	CIITA	P27361	MAPK3	S280	S286F	286	Missense	distal	6	no	19.345	18.631	PhosphoSitePlus;EPSD	COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P33076	CIITA	P27361	MAPK3	S280	S280Y	280	Missense	central	0	yes	19.345	0.000	PhosphoSitePlus;EPSD	COSMIC	9.358	Loss
CMGC_MAPK_ERK1_MAPK3_ST	P33076	CIITA	P27361	MAPK3	S280	G276S	276	Missense	distal	-4	no	19.345	19.383	PhosphoSitePlus;EPSD	COSMIC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P33076	CIITA	P27361	MAPK3	S288	A291S	291	Missense	distal	3	no	16.051	16.094	EPSD;PhosphoSitePlus	COSMIC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P33076	CIITA	P27361	MAPK3	S288	P281L	281	Missense	distal	-7	no	16.051	16.158	EPSD;PhosphoSitePlus	COSMIC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P33076	CIITA	P27361	MAPK3	S288	S286F	286	Missense	proximal	-2	no	16.051	14.751	EPSD;PhosphoSitePlus	COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P33076	CIITA	P27361	MAPK3	S288	P289L	289	Missense	proximal	1	no	16.051	7.013	EPSD;PhosphoSitePlus	COSMIC	9.358	Loss
CMGC_MAPK_ERK1_MAPK3_ST	P33076	CIITA	P27361	MAPK3	T740	R742K	742	Missense	proximal	2	no	17.067	17.063	EPSD	COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P33076	CIITA	P27361	MAPK3	T740	L739F	739	Missense	proximal	-1	no	17.067	16.951	EPSD	COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P33076	CIITA	P27361	MAPK3	T740	L733P	733	Missense	distal	-7	no	17.067	16.960	EPSD	COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P33076	CIITA	P27361	MAPK3	T740	P734R	734	Missense	distal	-6	no	17.067	16.991	EPSD	COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P33076	CIITA	P27361	MAPK3	T740	R745K	745	Missense	distal	5	no	17.067	17.058	EPSD	COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P33076	CIITA	P27361	MAPK3	S942	G949E	949	Missense	distal	7	no	9.374	9.339	EPSD	COSMIC	9.358	Loss
CMGC_MAPK_ERK1_MAPK3_ST	P78347	GTF2I	P27361	MAPK3	S210	G213E	213	Missense	distal	3	no	15.908	15.910	EPSD	COSMIC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P78347	GTF2I	P27361	MAPK3	S210	S214N	214	Missense	distal	4	no	15.908	15.761	EPSD	COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P78347	GTF2I	P27361	MAPK3	S515	R514I	514	Missense	proximal	-1	no	15.756	15.666	EPSD	COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P78347	GTF2I	P27361	MAPK3	T558	P559L	559	Missense	proximal	1	no	15.496	6.458	EPSD	COSMIC	9.358	Loss
CMGC_MAPK_ERK1_MAPK3_ST	P78347	GTF2I	P27361	MAPK3	S620	T622A	622	Missense	proximal	2	no	16.076	16.048	EPSD	COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P78347	GTF2I	P27361	MAPK3	S668	S668P	668	Missense	central	0	yes	18.117	0.000	EPSD	COSMIC	9.358	Loss
CMGC_MAPK_ERK1_MAPK3_ST	P78347	GTF2I	P27361	MAPK3	S674	S668P	668	Missense	distal	-6	no	17.285	17.201	EPSD	COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P78347	GTF2I	P27361	MAPK3	T703	T707I	707	Missense	distal	4	no	15.287	15.059	EPSD	COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P78347	GTF2I	P27361	MAPK3	S722	F721L	721	Missense	proximal	-1	no	9.743	9.858	EPSD	COSMIC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q14790	CASP8	P27361	MAPK3	S60	K63T	63	Missense	distal	3	no	9.486	9.496	EPSD	COSMIC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q14790	CASP8	P27361	MAPK3	S60	S60F	60	Missense	central	0	yes	9.486	0.000	EPSD	COSMIC	9.358	Loss
CMGC_MAPK_ERK1_MAPK3_ST	Q14790	CASP8	P27361	MAPK3	S60	L54S	54	Missense	distal	-6	no	9.486	9.818	EPSD	COSMIC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q14790	CASP8	P27361	MAPK3	S60	L65R	65	Missense	distal	5	no	9.486	9.613	EPSD	COSMIC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q14790	CASP8	P27361	MAPK3	S60	L66H	66	Missense	distal	6	no	9.486	9.620	EPSD	COSMIC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q14790	CASP8	P27361	MAPK3	S192	S186N	186	Missense	distal	-6	no	18.257	18.135	EPSD	COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q14790	CASP8	P27361	MAPK3	S192	S188A	188	Missense	distal	-4	no	18.257	18.125	EPSD	COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q14790	CASP8	P27361	MAPK3	S209	S211L	211	Missense	proximal	2	no	9.436	9.413	EPSD	COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q14790	CASP8	P27361	MAPK3	S209	C203G	203	Missense	distal	-6	no	9.436	9.933	EPSD	COSMIC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q14790	CASP8	P27361	MAPK3	S209	C203Y	203	Missense	distal	-6	no	9.436	9.742	EPSD	COSMIC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q14790	CASP8	P27361	MAPK3	S209	V205I	205	Missense	distal	-4	no	9.436	9.429	EPSD	COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q14790	CASP8	P27361	MAPK3	S209	S209L	209	Missense	central	0	yes	9.436	0.000	EPSD	COSMIC	9.358	Loss
CMGC_MAPK_ERK1_MAPK3_ST	Q14790	CASP8	P27361	MAPK3	S209	T207I	207	Missense	proximal	-2	no	9.436	8.584	EPSD	COSMIC	9.358	Loss
CMGC_MAPK_ERK1_MAPK3_ST	Q14790	CASP8	P27361	MAPK3	S209	S211C	211	Missense	proximal	2	no	9.436	9.375	EPSD	COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q14790	CASP8	P27361	MAPK3	S209	D216G	216	Missense	distal	7	no	9.436	9.469	EPSD	COSMIC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q14790	CASP8	P27361	MAPK3	S209	P212L	212	Missense	distal	3	no	9.436	9.400	EPSD	COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q14790	CASP8	P27361	MAPK3	S209	P212T	212	Missense	distal	3	no	9.436	9.418	EPSD	COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q14790	CASP8	P27361	MAPK3	S209	P212A	212	Missense	distal	3	no	9.436	9.388	EPSD	COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q14790	CASP8	P27361	MAPK3	S209	R213S	213	Missense	distal	4	no	9.436	9.583	EPSD	COSMIC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q14790	CASP8	P27361	MAPK3	S211	S211L	211	Missense	central	0	yes	16.399	0.000	EPSD	COSMIC	9.358	Loss
CMGC_MAPK_ERK1_MAPK3_ST	Q14790	CASP8	P27361	MAPK3	S211	V205I	205	Missense	distal	-6	no	16.399	16.330	EPSD	COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q14790	CASP8	P27361	MAPK3	S211	S209L	209	Missense	proximal	-2	no	16.399	16.091	EPSD	COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q14790	CASP8	P27361	MAPK3	S211	T207I	207	Missense	distal	-4	no	16.399	16.298	EPSD	COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q14790	CASP8	P27361	MAPK3	S211	S211C	211	Missense	central	0	yes	16.399	0.000	EPSD	COSMIC	9.358	Loss
CMGC_MAPK_ERK1_MAPK3_ST	Q14790	CASP8	P27361	MAPK3	S211	D216G	216	Missense	distal	5	no	16.399	16.376	EPSD	COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q14790	CASP8	P27361	MAPK3	S211	P212L	212	Missense	proximal	1	no	16.399	7.361	EPSD	COSMIC	9.358	Loss
CMGC_MAPK_ERK1_MAPK3_ST	Q14790	CASP8	P27361	MAPK3	S211	P212T	212	Missense	proximal	1	no	16.399	7.522	EPSD	COSMIC	9.358	Loss
CMGC_MAPK_ERK1_MAPK3_ST	Q14790	CASP8	P27361	MAPK3	S211	P212A	212	Missense	proximal	1	no	16.399	7.159	EPSD	COSMIC	9.358	Loss
CMGC_MAPK_ERK1_MAPK3_ST	Q14790	CASP8	P27361	MAPK3	S211	R213S	213	Missense	proximal	2	no	16.399	16.412	EPSD	COSMIC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q14790	CASP8	P27361	MAPK3	T221	L222P	222	Missense	proximal	1	no	6.231	15.269	EPSD	COSMIC	9.358	Gain
CMGC_MAPK_ERK1_MAPK3_ST	Q14790	CASP8	P27361	MAPK3	T273	E275D	275	Missense	proximal	2	no	9.733	9.731	EPSD	COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q14790	CASP8	P27361	MAPK3	T273	E275Q	275	Missense	proximal	2	no	9.733	9.720	EPSD	COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q14790	CASP8	P27361	MAPK3	T273	T273I	273	Missense	central	0	yes	9.733	0.000	EPSD	COSMIC	9.358	Loss
CMGC_MAPK_ERK1_MAPK3_ST	Q14790	CASP8	P27361	MAPK3	T273	H278L	278	Missense	distal	5	no	9.733	9.570	EPSD	COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q14790	CASP8	P27361	MAPK3	T273	L277F	277	Missense	distal	4	no	9.733	9.522	EPSD	COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q14790	CASP8	P27361	MAPK3	T273	D266N	266	Missense	distal	-7	no	9.733	9.758	EPSD	COSMIC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q14790	CASP8	P27361	MAPK3	T273	E280Q	280	Missense	distal	7	no	9.733	9.828	EPSD	COSMIC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q14790	CASP8	P27361	MAPK3	T273	E276K	276	Missense	distal	3	no	9.733	9.723	EPSD	COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q14790	CASP8	P27361	MAPK3	T273	A267T	267	Missense	distal	-6	no	9.733	9.881	EPSD	COSMIC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q14790	CASP8	P27361	MAPK3	T273	F274Y	274	Missense	proximal	1	no	9.733	8.899	EPSD	COSMIC	9.358	Loss
CMGC_MAPK_ERK1_MAPK3_ST	Q14790	CASP8	P27361	MAPK3	T273	F274L	274	Missense	proximal	1	no	9.733	6.909	EPSD	COSMIC	9.358	Loss
CMGC_MAPK_ERK1_MAPK3_ST	Q14790	CASP8	P27361	MAPK3	T273	T272M	272	Missense	proximal	-1	no	9.733	9.608	EPSD	COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q14790	CASP8	P27361	MAPK3	T273	E276V	276	Missense	distal	3	no	9.733	9.709	EPSD	COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q14790	CASP8	P27361	MAPK3	T273	F274C	274	Missense	proximal	1	no	9.733	0.639	EPSD	COSMIC	9.358	Loss
CMGC_MAPK_ERK1_MAPK3_ST	Q14790	CASP8	P27361	MAPK3	T273	H278N	278	Missense	distal	5	no	9.733	9.719	EPSD	COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q14790	CASP8	P27361	MAPK3	T273	G268V	268	Missense	distal	-5	no	9.733	9.701	EPSD	COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q14790	CASP8	P27361	MAPK3	T273	G268R	268	Missense	distal	-5	no	9.733	9.731	EPSD	COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q14790	CASP8	P27361	MAPK3	T273	H278Y	278	Missense	distal	5	no	9.733	9.625	EPSD	COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q14790	CASP8	P27361	MAPK3	S387	L385P	385	Missense	proximal	-2	no	18.014	19.398	PhosphoSitePlus	COSMIC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q14790	CASP8	P27361	MAPK3	S387	T390I	390	Missense	distal	3	no	18.014	17.976	PhosphoSitePlus	COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q14790	CASP8	P27361	MAPK3	S387	P394L	394	Missense	distal	7	no	18.014	18.206	PhosphoSitePlus	COSMIC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q14790	CASP8	P27361	MAPK3	S387	D384N	384	Missense	distal	-3	no	18.014	17.992	PhosphoSitePlus	COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q14790	CASP8	P27361	MAPK3	S387	P388S	388	Missense	proximal	1	no	18.014	8.960	PhosphoSitePlus	COSMIC;CCLE	9.358	Loss
CMGC_MAPK_ERK1_MAPK3_ST	Q14790	CASP8	P27361	MAPK3	S387	P394S	394	Missense	distal	7	no	18.014	17.936	PhosphoSitePlus	COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q14790	CASP8	P27361	MAPK3	S387	R391G	391	Missense	distal	4	no	18.014	18.000	PhosphoSitePlus	COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q14790	CASP8	P27361	MAPK3	S387	P394Q	394	Missense	distal	7	no	18.014	18.136	PhosphoSitePlus	COSMIC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q14790	CASP8	P27361	MAPK3	S387	T390M	390	Missense	distal	3	no	18.014	17.965	PhosphoSitePlus	COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q14790	CASP8	P27361	MAPK3	S387	P388L	388	Missense	proximal	1	no	18.014	8.976	PhosphoSitePlus	COSMIC	9.358	Loss
CMGC_MAPK_ERK1_MAPK3_ST	Q14790	CASP8	P27361	MAPK3	S387	S386L	386	Missense	proximal	-1	no	18.014	17.925	PhosphoSitePlus	COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q14790	CASP8	P27361	MAPK3	S387	P394T	394	Missense	distal	7	no	18.014	18.055	PhosphoSitePlus	COSMIC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q14790	CASP8	P27361	MAPK3	T469	L474P	474	Missense	distal	5	no	9.209	9.436	EPSD	COSMIC	9.358	Gain
CMGC_MAPK_ERK1_MAPK3_ST	Q9BR01	SULT4A1	P27361	MAPK3	T8	P9A	9	Missense	proximal	1	no	15.149	5.910	EPSD	COSMIC	9.358	Loss
CMGC_MAPK_ERK1_MAPK3_ST	Q9BR01	SULT4A1	P27361	MAPK3	T8	F15L	15	Missense	distal	7	no	15.149	14.928	EPSD	COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q9BR01	SULT4A1	P27361	MAPK3	T8	P12L	12	Missense	distal	4	no	15.149	14.995	EPSD	COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q9BR01	SULT4A1	P27361	MAPK3	T11	P9A	9	Missense	proximal	-2	no	17.810	15.459	PhosphoSitePlus	COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q9BR01	SULT4A1	P27361	MAPK3	T11	F15L	15	Missense	distal	4	no	17.810	18.021	PhosphoSitePlus	COSMIC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q9BR01	SULT4A1	P27361	MAPK3	T11	P12L	12	Missense	proximal	1	no	17.810	8.772	PhosphoSitePlus	COSMIC	9.358	Loss
CMGC_MAPK_ERK1_MAPK3_ST	O43521	BCL2L11	P27361	MAPK3	S59	P60S	60	Missense	proximal	1	no	16.761	7.707	EPSD	COSMIC	9.358	Loss
CMGC_MAPK_ERK1_MAPK3_ST	O43521	BCL2L11	P27361	MAPK3	S59	P66S	66	Missense	distal	7	no	16.761	16.683	EPSD	COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	O43521	BCL2L11	P27361	MAPK3	S59	G58S	58	Missense	proximal	-1	no	16.761	16.827	EPSD	COSMIC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	O43521	BCL2L11	P27361	MAPK3	S69	P66S	66	Missense	distal	-3	no	18.489	18.481	PhosphoSitePlus	COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	O43521	BCL2L11	P27361	MAPK3	S69	A74V	74	Missense	distal	5	no	18.489	18.478	PhosphoSitePlus	COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	O43521	BCL2L11	P27361	MAPK3	S69	P72S	72	Missense	distal	3	no	18.489	18.485	PhosphoSitePlus	COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	O43521	BCL2L11	P27361	MAPK3	S69	R76K	76	Missense	distal	7	no	18.489	18.495	PhosphoSitePlus	COSMIC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	O43521	BCL2L11	P27361	MAPK3	S69	R76S	76	Missense	distal	7	no	18.489	18.320	PhosphoSitePlus	COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	O43521	BCL2L11	P27361	MAPK3	S77	P78S	78	Missense	proximal	1	no	15.478	6.424	EPSD	COSMIC	9.358	Loss
CMGC_MAPK_ERK1_MAPK3_ST	O43521	BCL2L11	P27361	MAPK3	S77	A74V	74	Missense	distal	-3	no	15.478	15.497	EPSD	COSMIC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	O43521	BCL2L11	P27361	MAPK3	S77	P72S	72	Missense	distal	-5	no	15.478	15.483	EPSD	COSMIC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	O43521	BCL2L11	P27361	MAPK3	S77	R76K	76	Missense	proximal	-1	no	15.478	15.464	EPSD	COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	O43521	BCL2L11	P27361	MAPK3	S77	R84K	84	Missense	distal	7	no	15.478	15.483	EPSD	COSMIC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	O43521	BCL2L11	P27361	MAPK3	S77	R76S	76	Missense	proximal	-1	no	15.478	15.519	EPSD	COSMIC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	O43521	BCL2L11	P27361	MAPK3	S77	P78L	78	Missense	proximal	1	no	15.478	6.440	EPSD	COSMIC;GDSC;CCLE	9.358	Loss
CMGC_MAPK_ERK1_MAPK3_ST	O43521	BCL2L11	P27361	MAPK3	S92	S93F	93	Missense	proximal	1	no	7.900	10.740	EPSD	COSMIC	9.358	Gain
CMGC_MAPK_ERK1_MAPK3_ST	O43521	BCL2L11	P27361	MAPK3	S98	S104R	104	Missense	distal	6	no	10.615	10.373	EPSD	COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	O43521	BCL2L11	P27361	MAPK3	S98	F97L	97	Missense	proximal	-1	no	10.615	10.730	EPSD	COSMIC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	O43521	BCL2L11	P27361	MAPK3	S98	D100G	100	Missense	proximal	2	no	10.615	10.610	EPSD	COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	O43521	BCL2L11	P27361	MAPK3	S98	S93F	93	Missense	distal	-5	no	10.615	10.481	EPSD	COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	O43521	BCL2L11	P27361	MAPK3	S98	S94T	94	Missense	distal	-4	no	10.615	10.557	EPSD	COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	O43521	BCL2L11	P27361	MAPK3	S104	A106S	106	Missense	proximal	2	no	14.210	14.249	EPSD	COSMIC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	O43521	BCL2L11	P27361	MAPK3	S104	S104R	104	Missense	central	0	yes	14.210	0.000	EPSD	COSMIC	9.358	Loss
CMGC_MAPK_ERK1_MAPK3_ST	O43521	BCL2L11	P27361	MAPK3	S104	F97L	97	Missense	distal	-7	no	14.210	14.136	EPSD	COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	O43521	BCL2L11	P27361	MAPK3	S104	D100G	100	Missense	distal	-4	no	14.210	14.207	EPSD	COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	O43521	BCL2L11	P27361	MAPK3	T116	P120S	120	Missense	distal	4	no	16.362	16.411	EPSD	COSMIC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	O43521	BCL2L11	P27361	MAPK3	S118	P120S	120	Missense	proximal	2	no	17.819	17.821	EPSD	COSMIC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q9ULC4	MCTS1	P27361	MAPK3	S118	P114S	114	Missense	distal	-4	no	14.525	14.552	EPSD	COSMIC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P42229	STAT5A	P27361	MAPK3	S128	P129L	129	Missense	proximal	1	no	12.917	3.879	EPSD	COSMIC	9.358	Loss
CMGC_MAPK_ERK1_MAPK3_ST	P42229	STAT5A	P27361	MAPK3	S128	D135H	135	Missense	distal	7	no	12.917	12.948	EPSD	COSMIC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P42229	STAT5A	P27361	MAPK3	S128	S128F	128	Missense	central	0	yes	12.917	0.000	EPSD	COSMIC	9.358	Loss
CMGC_MAPK_ERK1_MAPK3_ST	P42229	STAT5A	P27361	MAPK3	S193	A187G	187	Missense	distal	-6	no	16.457	16.711	EPSD	COSMIC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P42229	STAT5A	P27361	MAPK3	S193	R200W	200	Missense	distal	7	no	16.457	17.034	EPSD	COSMIC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P42229	STAT5A	P27361	MAPK3	S193	Q188P	188	Missense	distal	-5	no	16.457	16.505	EPSD	COSMIC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P42229	STAT5A	P27361	MAPK3	S193	R200L	200	Missense	distal	7	no	16.457	16.558	EPSD	COSMIC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P42229	STAT5A	P27361	MAPK3	S193	S193R	193	Missense	central	0	yes	16.457	0.000	EPSD	COSMIC	9.358	Loss
CMGC_MAPK_ERK1_MAPK3_ST	P42229	STAT5A	P27361	MAPK3	S726	P725L	725	Missense	proximal	-1	no	15.734	15.639	EPSD	COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P42229	STAT5A	P27361	MAPK3	S726	P731T	731	Missense	distal	5	no	15.734	15.641	EPSD	COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P42229	STAT5A	P27361	MAPK3	S726	P725H	725	Missense	proximal	-1	no	15.734	15.689	EPSD	COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P42229	STAT5A	P27361	MAPK3	S726	D722N	722	Missense	distal	-4	no	15.734	15.708	EPSD	COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P42229	STAT5A	P27361	MAPK3	S777	R778C	778	Missense	proximal	1	no	9.885	4.078	EPSD	COSMIC;CCLE	9.358	Loss
CMGC_MAPK_ERK1_MAPK3_ST	P42229	STAT5A	P27361	MAPK3	S777	S780L	780	Missense	distal	3	no	9.885	9.853	EPSD	COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P42229	STAT5A	P27361	MAPK3	S777	S774T	774	Missense	distal	-3	no	9.885	9.855	EPSD	COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P42229	STAT5A	P27361	MAPK3	S777	R770Q	770	Missense	distal	-7	no	9.885	9.884	EPSD	COSMIC;GDSC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P42229	STAT5A	P27361	MAPK3	S777	S777Y	777	Missense	central	0	yes	9.885	0.000	EPSD	COSMIC;GDSC	9.358	Loss
CMGC_MAPK_ERK1_MAPK3_ST	P42229	STAT5A	P27361	MAPK3	S780	R778C	778	Missense	proximal	-2	no	18.628	16.512	PhosphoSitePlus	COSMIC;CCLE	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P42229	STAT5A	P27361	MAPK3	S780	S780L	780	Missense	central	0	yes	18.628	0.000	PhosphoSitePlus	COSMIC	9.358	Loss
CMGC_MAPK_ERK1_MAPK3_ST	P42229	STAT5A	P27361	MAPK3	S780	S774T	774	Missense	distal	-6	no	18.628	18.459	PhosphoSitePlus	COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P42229	STAT5A	P27361	MAPK3	S780	S777Y	777	Missense	distal	-3	no	18.628	18.565	PhosphoSitePlus	COSMIC;GDSC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P42229	STAT5A	P27361	MAPK3	T787	S780L	780	Missense	distal	-7	no	9.323	9.467	EPSD	COSMIC	9.358	Gain
CMGC_MAPK_ERK1_MAPK3_ST	Q15366	PCBP2	P27361	MAPK3	S173	P174S	174	Missense	proximal	1	no	16.839	7.786	EPSD;PhosphoSitePlus	COSMIC	9.358	Loss
CMGC_MAPK_ERK1_MAPK3_ST	Q15366	PCBP2	P27361	MAPK3	S173	M166V	166	Missense	distal	-7	no	16.839	16.783	EPSD;PhosphoSitePlus	COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q15366	PCBP2	P27361	MAPK3	S173	V178A	178	Missense	distal	5	no	16.839	16.850	EPSD;PhosphoSitePlus	COSMIC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q15366	PCBP2	P27361	MAPK3	S173	V178M	178	Missense	distal	5	no	16.839	16.715	EPSD;PhosphoSitePlus	COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q15366	PCBP2	P27361	MAPK3	S188	P186L	186	Missense	proximal	-2	no	9.654	8.270	EPSD	COSMIC	9.358	Loss
CMGC_MAPK_ERK1_MAPK3_ST	Q15366	PCBP2	P27361	MAPK3	S189	P186L	186	Missense	distal	-3	no	16.547	16.463	EPSD;PhosphoSitePlus	COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q15366	PCBP2	P27361	MAPK3	S208	P214S	214	Missense	distal	6	no	11.745	11.875	EPSD	COSMIC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q15366	PCBP2	P27361	MAPK3	S208	S215T	215	Missense	distal	7	no	11.745	11.864	EPSD	COSMIC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q15366	PCBP2	P27361	MAPK3	S208	P210S	210	Missense	proximal	2	no	11.745	11.747	EPSD	COSMIC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q15366	PCBP2	P27361	MAPK3	S208	G203V	203	Missense	distal	-5	no	11.745	11.713	EPSD	COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q15366	PCBP2	P27361	MAPK3	T213	P214S	214	Missense	proximal	1	no	14.340	5.287	EPSD;PhosphoSitePlus	COSMIC	9.358	Loss
CMGC_MAPK_ERK1_MAPK3_ST	Q15366	PCBP2	P27361	MAPK3	T213	S215T	215	Missense	proximal	2	no	14.340	14.329	EPSD;PhosphoSitePlus	COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q15366	PCBP2	P27361	MAPK3	T213	P210S	210	Missense	distal	-3	no	14.340	14.332	EPSD;PhosphoSitePlus	COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q15366	PCBP2	P27361	MAPK3	S272	S271R	271	Missense	proximal	-1	no	17.860	17.818	PhosphoSitePlus;EPSD	COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q15366	PCBP2	P27361	MAPK3	S272	S270T	270	Missense	proximal	-2	no	17.860	17.950	PhosphoSitePlus;EPSD	COSMIC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q15366	PCBP2	P27361	MAPK3	S272	S266T	266	Missense	distal	-6	no	17.860	17.692	PhosphoSitePlus;EPSD	COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q15366	PCBP2	P27361	MAPK3	S340	V335F	335	Missense	distal	-5	no	10.281	10.222	EPSD	COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q8N9N5	BANP	P27361	MAPK3	S90	S90N	90	Missense	central	0	yes	14.270	0.000	EPSD	COSMIC	9.358	Loss
CMGC_MAPK_ERK1_MAPK3_ST	Q8N9N5	BANP	P27361	MAPK3	S100	S100F	100	Missense	central	0	yes	16.242	0.000	EPSD	COSMIC	9.358	Loss
CMGC_MAPK_ERK1_MAPK3_ST	Q8N9N5	BANP	P27361	MAPK3	S334	R335Q	335	Missense	proximal	1	no	8.285	9.842	EPSD	COSMIC	9.358	Gain
CMGC_MAPK_ERK1_MAPK3_ST	Q8N9N5	BANP	P27361	MAPK3	T337	R335Q	335	Missense	proximal	-2	no	16.081	15.717	PhosphoSitePlus;EPSD	COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q8N9N5	BANP	P27361	MAPK3	T337	S341P	341	Missense	distal	4	no	16.081	16.032	PhosphoSitePlus;EPSD	COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q8N9N5	BANP	P27361	MAPK3	T337	S332R	332	Missense	distal	-5	no	16.081	16.035	PhosphoSitePlus;EPSD	COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q8N9N5	BANP	P27361	MAPK3	T352	P348S	348	Missense	distal	-4	no	14.465	14.492	EPSD;PhosphoSitePlus	COSMIC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q8N9N5	BANP	P27361	MAPK3	T352	S357R	357	Missense	distal	5	no	14.465	14.321	EPSD;PhosphoSitePlus	COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q16559	TAL2	P27361	MAPK3	S100	P101H	101	Missense	proximal	1	no	19.528	11.772	PhosphoSitePlus	COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	O00429	DNM1L	P27361	MAPK3	S126	S119L	119	Missense	distal	-7	no	16.284	16.429	EPSD	COSMIC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	O00429	DNM1L	P27361	MAPK3	S126	K133N	133	Missense	distal	7	no	16.284	16.275	EPSD	COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	O00429	DNM1L	P27361	MAPK3	S126	G124E	124	Missense	proximal	-2	no	16.284	16.755	EPSD	COSMIC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	O00429	DNM1L	P27361	MAPK3	S126	G124R	124	Missense	proximal	-2	no	16.284	17.001	EPSD	COSMIC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	O00429	DNM1L	P27361	MAPK3	S126	G120C	120	Missense	distal	-6	no	16.284	15.788	EPSD	COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	O00429	DNM1L	P27361	MAPK3	S136	K133N	133	Missense	distal	-3	no	16.887	16.893	EPSD	COSMIC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	O00429	DNM1L	P27361	MAPK3	S412	V417A	417	Missense	distal	5	no	10.500	10.511	EPSD	COSMIC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	O00429	DNM1L	P27361	MAPK3	S412	R419W	419	Missense	distal	7	no	10.500	11.076	EPSD	COSMIC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	O00429	DNM1L	P27361	MAPK3	S412	P409S	409	Missense	distal	-3	no	10.500	10.491	EPSD	COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	O00429	DNM1L	P27361	MAPK3	S544	A543S	543	Missense	proximal	-1	no	9.422	9.556	EPSD	COSMIC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	O00429	DNM1L	P27361	MAPK3	S544	A539V	539	Missense	distal	-5	no	9.422	9.445	EPSD	COSMIC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	O00429	DNM1L	P27361	MAPK3	S544	Q545K	545	Missense	proximal	1	no	9.422	0.213	EPSD	COSMIC	9.358	Loss
CMGC_MAPK_ERK1_MAPK3_ST	O00429	DNM1L	P27361	MAPK3	S544	S538N	538	Missense	distal	-6	no	9.422	9.300	EPSD	COSMIC	9.358	Loss
CMGC_MAPK_ERK1_MAPK3_ST	O00429	DNM1L	P27361	MAPK3	S548	A543S	543	Missense	distal	-5	no	16.860	16.959	EPSD	COSMIC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	O00429	DNM1L	P27361	MAPK3	S548	Q545K	545	Missense	distal	-3	no	16.860	16.855	EPSD	COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	O00429	DNM1L	P27361	MAPK3	S616	P611L	611	Missense	distal	-5	no	18.171	18.116	PhosphoSitePlus	COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	O00429	DNM1L	P27361	MAPK3	S616	A622D	622	Missense	distal	6	no	18.171	18.520	PhosphoSitePlus	COSMIC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P17542	TAL1	P27361	MAPK3	S172	R169K	169	Missense	distal	-3	no	14.841	14.828	EPSD	COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P17542	TAL1	P27361	MAPK3	S172	M176I	176	Missense	distal	4	no	14.841	14.878	EPSD	COSMIC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P17542	TAL1	P27361	MAPK3	S172	E175K	175	Missense	distal	3	no	14.841	14.831	EPSD	COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P17542	TAL1	P27361	MAPK3	S172	S172Y	172	Missense	central	0	yes	14.841	0.000	EPSD	COSMIC	9.358	Loss
CMGC_MAPK_ERK1_MAPK3_ST	P17542	TAL1	P27361	MAPK3	S172	T179S	179	Missense	distal	7	no	14.841	14.723	EPSD	COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P17542	TAL1	P27361	MAPK3	S172	P171H	171	Missense	proximal	-1	no	14.841	14.796	EPSD	COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P17542	TAL1	P27361	MAPK3	S300	D302Y	302	Missense	proximal	2	no	15.182	15.171	EPSD	COSMIC;GDSC;CCLE	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P17542	TAL1	P27361	MAPK3	S300	S300N	300	Missense	central	0	yes	15.182	0.000	EPSD	COSMIC	9.358	Loss
CMGC_MAPK_ERK1_MAPK3_ST	P17542	TAL1	P27361	MAPK3	S300	S303R	303	Missense	distal	3	no	15.182	15.160	EPSD	COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P17542	TAL1	P27361	MAPK3	S300	G297V	297	Missense	distal	-3	no	15.182	15.142	EPSD	COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P17542	TAL1	P27361	MAPK3	S303	D302Y	302	Missense	proximal	-1	no	11.936	11.906	EPSD	COSMIC;GDSC;CCLE	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P17542	TAL1	P27361	MAPK3	S303	S300N	300	Missense	distal	-3	no	11.936	11.892	EPSD	COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P17542	TAL1	P27361	MAPK3	S303	S303R	303	Missense	central	0	yes	11.936	0.000	EPSD	COSMIC	9.358	Loss
CMGC_MAPK_ERK1_MAPK3_ST	P17542	TAL1	P27361	MAPK3	S303	G297V	297	Missense	distal	-6	no	11.936	11.669	EPSD	COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P17542	TAL1	P27361	MAPK3	S303	P308T	308	Missense	distal	5	no	11.936	11.844	EPSD	COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P17542	TAL1	P27361	MAPK3	T313	R315H	315	Missense	proximal	2	no	9.647	9.644	EPSD	COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P17542	TAL1	P27361	MAPK3	T313	R315L	315	Missense	proximal	2	no	9.647	9.636	EPSD	COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P17542	TAL1	P27361	MAPK3	T313	A314T	314	Missense	proximal	1	no	9.647	10.009	EPSD	COSMIC;CCLE	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P17542	TAL1	P27361	MAPK3	T313	T313M	313	Missense	central	0	yes	9.647	0.000	EPSD	COSMIC	9.358	Loss
CMGC_MAPK_ERK1_MAPK3_ST	P17542	TAL1	P27361	MAPK3	T313	P308T	308	Missense	distal	-5	no	9.647	9.636	EPSD	COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P17542	TAL1	P27361	MAPK3	S316	R315H	315	Missense	proximal	-1	no	9.898	9.901	EPSD	COSMIC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P17542	TAL1	P27361	MAPK3	S316	R315L	315	Missense	proximal	-1	no	9.898	9.851	EPSD	COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P17542	TAL1	P27361	MAPK3	S316	A314T	314	Missense	proximal	-2	no	9.898	11.263	EPSD	COSMIC;CCLE	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P17542	TAL1	P27361	MAPK3	S316	T313M	313	Missense	distal	-3	no	9.898	9.801	EPSD	COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q13485	SMAD4	P27361	MAPK3	T9	A15V	15	Missense	distal	6	no	14.802	14.889	EPSD	COSMIC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q13485	SMAD4	P27361	MAPK3	T9	A15T	15	Missense	distal	6	no	14.802	15.173	EPSD	COSMIC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q13485	SMAD4	P27361	MAPK3	T9	I6V	6	Missense	distal	-3	no	14.802	14.841	EPSD	COSMIC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q13485	SMAD4	P27361	MAPK3	T9	N3D	3	Missense	distal	-6	no	14.802	14.864	EPSD	COSMIC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q13485	SMAD4	P27361	MAPK3	S138	L143F	143	Missense	distal	5	no	15.185	15.031	EPSD	COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q13485	SMAD4	P27361	MAPK3	S138	E134D	134	Missense	distal	-4	no	15.185	15.173	EPSD	COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q13485	SMAD4	P27361	MAPK3	S138	R135Q	135	Missense	distal	-3	no	15.185	15.177	EPSD	COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q13485	SMAD4	P27361	MAPK3	S138	Y133H	133	Missense	distal	-5	no	15.185	15.212	EPSD	COSMIC;GDSC;CCLE	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q13485	SMAD4	P27361	MAPK3	S138	G140E	140	Missense	proximal	2	no	15.185	15.193	EPSD	COSMIC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q13485	SMAD4	P27361	MAPK3	S138	H132L	132	Missense	distal	-6	no	15.185	15.018	EPSD	COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q13485	SMAD4	P27361	MAPK3	S138	L143H	143	Missense	distal	5	no	15.185	15.347	EPSD	COSMIC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q13485	SMAD4	P27361	MAPK3	S138	S138L	138	Missense	central	0	yes	15.185	0.000	EPSD	COSMIC	9.358	Loss
CMGC_MAPK_ERK1_MAPK3_ST	Q13485	SMAD4	P27361	MAPK3	S138	H132N	132	Missense	distal	-6	no	15.185	15.227	EPSD	COSMIC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q13485	SMAD4	P27361	MAPK3	T277	A274E	274	Missense	distal	-3	no	16.892	16.964	PhosphoSitePlus	COSMIC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q13485	SMAD4	P27361	MAPK3	T277	P275S	275	Missense	proximal	-2	no	16.892	15.816	PhosphoSitePlus	COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q13485	SMAD4	P27361	MAPK3	T277	P275L	275	Missense	proximal	-2	no	16.892	15.508	PhosphoSitePlus	COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q13485	SMAD4	P27361	MAPK3	T277	R272S	272	Missense	distal	-5	no	16.892	16.938	PhosphoSitePlus	COSMIC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q13485	SMAD4	P27361	MAPK3	T277	T273S	273	Missense	distal	-4	no	16.892	16.950	PhosphoSitePlus	COSMIC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q13485	SMAD4	P27361	MAPK3	T277	P281L	281	Missense	distal	4	no	16.892	16.738	PhosphoSitePlus	COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q13485	SMAD4	P27361	MAPK3	T277	T277R	277	Missense	central	0	yes	16.892	0.000	PhosphoSitePlus	COSMIC	9.358	Loss
CMGC_MAPK_ERK1_MAPK3_ST	Q13485	SMAD4	P27361	MAPK3	S504	G508S	508	Missense	distal	4	no	9.251	9.412	EPSD	COSMIC	9.358	Gain
CMGC_MAPK_ERK1_MAPK3_ST	Q13485	SMAD4	P27361	MAPK3	S504	P511L	511	Missense	distal	7	no	9.251	9.444	EPSD	COSMIC	9.358	Gain
CMGC_MAPK_ERK1_MAPK3_ST	Q13485	SMAD4	P27361	MAPK3	S504	P511Q	511	Missense	distal	7	no	9.251	9.373	EPSD	COSMIC	9.358	Gain
CMGC_MAPK_ERK1_MAPK3_ST	P00533	EGFR	P27361	MAPK3	S77	L76P	76	Missense	proximal	-1	no	10.908	11.003	EPSD	COSMIC;GDSC;CCLE	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P00533	EGFR	P27361	MAPK3	S227	G221V	221	Missense	distal	-6	no	15.963	15.696	EPSD	COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P00533	EGFR	P27361	MAPK3	S227	R222H	222	Missense	distal	-5	no	15.963	15.973	EPSD	COSMIC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P00533	EGFR	P27361	MAPK3	S227	G221W	221	Missense	distal	-6	no	15.963	15.343	EPSD	COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P00533	EGFR	P27361	MAPK3	S227	S227Y	227	Missense	central	0	yes	15.963	0.000	EPSD	COSMIC	9.358	Loss
CMGC_MAPK_ERK1_MAPK3_ST	P00533	EGFR	P27361	MAPK3	S227	G225C	225	Missense	proximal	-2	no	15.963	14.564	EPSD	COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P00533	EGFR	P27361	MAPK3	S227	S220F	220	Missense	distal	-7	no	15.963	16.182	EPSD	COSMIC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P00533	EGFR	P27361	MAPK3	S227	C231S	231	Missense	distal	4	no	15.963	16.467	EPSD	COSMIC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P00533	EGFR	P27361	MAPK3	S229	R222H	222	Missense	distal	-7	no	10.196	10.185	EPSD	COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P00533	EGFR	P27361	MAPK3	S229	S227Y	227	Missense	proximal	-2	no	10.196	9.963	EPSD	COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P00533	EGFR	P27361	MAPK3	S229	G225C	225	Missense	distal	-4	no	10.196	9.997	EPSD	COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P00533	EGFR	P27361	MAPK3	S229	C231S	231	Missense	proximal	2	no	10.196	10.258	EPSD	COSMIC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P00533	EGFR	P27361	MAPK3	S511	A508V	508	Missense	distal	-3	no	15.023	15.042	EPSD	COSMIC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P00533	EGFR	P27361	MAPK3	S511	L509F	509	Missense	proximal	-2	no	15.023	14.031	EPSD	COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P00533	EGFR	P27361	MAPK3	S511	S511Y	511	Missense	central	0	yes	15.023	0.000	EPSD	COSMIC	9.358	Loss
CMGC_MAPK_ERK1_MAPK3_ST	P00533	EGFR	P27361	MAPK3	T693	A698V	698	Missense	distal	5	no	18.879	18.868	PhosphoSitePlus	COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P00533	EGFR	P27361	MAPK3	T693	P691T	691	Missense	proximal	-2	no	18.879	17.893	PhosphoSitePlus	COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P00533	EGFR	P27361	MAPK3	T693	L688P	688	Missense	distal	-5	no	18.879	18.934	PhosphoSitePlus	COSMIC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P00533	EGFR	P27361	MAPK3	T693	P699S	699	Missense	distal	6	no	18.879	19.009	PhosphoSitePlus	COSMIC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P00533	EGFR	P27361	MAPK3	T693	V689M	689	Missense	distal	-4	no	18.879	18.851	PhosphoSitePlus	COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P00533	EGFR	P27361	MAPK3	T693	N700Y	700	Missense	distal	7	no	18.879	18.968	PhosphoSitePlus	COSMIC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P00533	EGFR	P27361	MAPK3	T693	L692P	692	Missense	proximal	-1	no	18.879	18.973	PhosphoSitePlus	COSMIC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P00533	EGFR	P27361	MAPK3	T693	P694S	694	Missense	proximal	1	no	18.879	9.825	PhosphoSitePlus	COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P00533	EGFR	P27361	MAPK3	T693	N700S	700	Missense	distal	7	no	18.879	18.713	PhosphoSitePlus	COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P00533	EGFR	P27361	MAPK3	T693	E690K	690	Missense	distal	-3	no	18.879	18.848	PhosphoSitePlus	COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P00533	EGFR	P27361	MAPK3	T693	P691S	691	Missense	proximal	-2	no	18.879	17.803	PhosphoSitePlus	COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P00533	EGFR	P27361	MAPK3	T693	V689L	689	Missense	distal	-4	no	18.879	18.891	PhosphoSitePlus	COSMIC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P00533	EGFR	P27361	MAPK3	T693	E697D	697	Missense	distal	4	no	18.879	18.859	PhosphoSitePlus	COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P00533	EGFR	P27361	MAPK3	T693	P694L	694	Missense	proximal	1	no	18.879	9.841	PhosphoSitePlus	COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P00533	EGFR	P27361	MAPK3	T693	L688F	688	Missense	distal	-5	no	18.879	18.804	PhosphoSitePlus	COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P00533	EGFR	P27361	MAPK3	T693	N700D	700	Missense	distal	7	no	18.879	18.820	PhosphoSitePlus	COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P00533	EGFR	P27361	MAPK3	T693	S695G	695	Missense	proximal	2	no	18.879	18.862	PhosphoSitePlus	COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P00533	EGFR	P27361	MAPK3	T693	R686S	686	Missense	distal	-7	no	18.879	18.796	PhosphoSitePlus	COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P00533	EGFR	P27361	MAPK3	T693	T693A	693	Missense	central	0	yes	18.879	0.000	PhosphoSitePlus	COSMIC	9.358	Loss
CMGC_MAPK_ERK1_MAPK3_ST	P00533	EGFR	P27361	MAPK3	T693	E690V	690	Missense	distal	-3	no	18.879	18.826	PhosphoSitePlus	COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P00533	EGFR	P27361	MAPK3	T693	L692F	692	Missense	proximal	-1	no	18.879	18.764	PhosphoSitePlus	COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P00533	EGFR	P27361	MAPK3	T693	G696R	696	Missense	distal	3	no	18.879	18.872	PhosphoSitePlus	COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P00533	EGFR	P27361	MAPK3	T693	G696E	696	Missense	distal	3	no	18.879	18.881	PhosphoSitePlus	COSMIC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P00533	EGFR	P27361	MAPK3	S752	L747P	747	Missense	distal	-5	no	15.913	15.967	EPSD	COSMIC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P00533	EGFR	P27361	MAPK3	S752	L747F	747	Missense	distal	-5	no	15.913	15.838	EPSD	COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P00533	EGFR	P27361	MAPK3	S752	L747H	747	Missense	distal	-5	no	15.913	15.936	EPSD	COSMIC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P00533	EGFR	P27361	MAPK3	S752	L747S	747	Missense	distal	-5	no	15.913	15.972	EPSD	COSMIC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P00533	EGFR	P27361	MAPK3	S752	A750P	750	Missense	proximal	-2	no	15.913	18.263	EPSD	COSMIC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P00533	EGFR	P27361	MAPK3	S752	R748K	748	Missense	distal	-4	no	15.913	15.906	EPSD	COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P00533	EGFR	P27361	MAPK3	S752	I759V	759	Missense	distal	7	no	15.913	15.832	EPSD	COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P00533	EGFR	P27361	MAPK3	S752	K754Q	754	Missense	proximal	2	no	15.913	15.907	EPSD	COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P00533	EGFR	P27361	MAPK3	S752	T751A	751	Missense	proximal	-1	no	15.913	15.809	EPSD	COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P00533	EGFR	P27361	MAPK3	S752	E758G	758	Missense	distal	6	no	15.913	15.812	EPSD	COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P00533	EGFR	P27361	MAPK3	S752	K757N	757	Missense	distal	5	no	15.913	15.942	EPSD	COSMIC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P00533	EGFR	P27361	MAPK3	S752	S752Y	752	Missense	central	0	yes	15.913	0.000	EPSD	COSMIC	9.358	Loss
CMGC_MAPK_ERK1_MAPK3_ST	P00533	EGFR	P27361	MAPK3	S752	T751I	751	Missense	proximal	-1	no	15.913	15.811	EPSD	COSMIC;GDSC;CCLE	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P00533	EGFR	P27361	MAPK3	S752	E746V	746	Missense	distal	-6	no	15.913	15.599	EPSD	COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P00533	EGFR	P27361	MAPK3	S752	A750T	750	Missense	proximal	-2	no	15.913	17.278	EPSD	COSMIC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P00533	EGFR	P27361	MAPK3	S752	S752F	752	Missense	central	0	yes	15.913	0.000	EPSD	COSMIC	9.358	Loss
CMGC_MAPK_ERK1_MAPK3_ST	P00533	EGFR	P27361	MAPK3	S752	E746A	746	Missense	distal	-6	no	15.913	15.613	EPSD	COSMIC;GDSC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P00533	EGFR	P27361	MAPK3	S752	A755D	755	Missense	distal	3	no	15.913	15.946	EPSD	COSMIC;CCLE	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P00533	EGFR	P27361	MAPK3	S752	K754R	754	Missense	proximal	2	no	15.913	15.916	EPSD	COSMIC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P00533	EGFR	P27361	MAPK3	S752	E749K	749	Missense	distal	-3	no	15.913	15.881	EPSD	COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P00533	EGFR	P27361	MAPK3	S752	T751L	751	Missense	proximal	-1	no	15.913	15.854	EPSD	COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P00533	EGFR	P27361	MAPK3	S752	E758K	758	Missense	distal	6	no	15.913	15.836	EPSD	COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P00533	EGFR	P27361	MAPK3	S752	K745R	745	Missense	distal	-7	no	15.913	15.912	EPSD	COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P00533	EGFR	P27361	MAPK3	S752	E746I	746	Missense	distal	-6	no	15.913	15.531	EPSD	COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P00533	EGFR	P27361	MAPK3	S752	A755T	755	Missense	distal	3	no	15.913	15.943	EPSD	COSMIC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P00533	EGFR	P27361	MAPK3	S752	K754A	754	Missense	proximal	2	no	15.913	15.890	EPSD	COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P00533	EGFR	P27361	MAPK3	S752	N756S	756	Missense	distal	4	no	15.913	16.059	EPSD	COSMIC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P00533	EGFR	P27361	MAPK3	S752	N756Y	756	Missense	distal	4	no	15.913	15.843	EPSD	COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P00533	EGFR	P27361	MAPK3	S752	K757R	757	Missense	distal	5	no	15.913	15.921	EPSD	COSMIC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P00533	EGFR	P27361	MAPK3	S752	A755G	755	Missense	distal	3	no	15.913	15.941	EPSD	COSMIC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P00533	EGFR	P27361	MAPK3	S752	E746G	746	Missense	distal	-6	no	15.913	15.867	EPSD	COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P00533	EGFR	P27361	MAPK3	S752	E749V	749	Missense	distal	-3	no	15.913	15.860	EPSD	COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P00533	EGFR	P27361	MAPK3	S752	E749G	749	Missense	distal	-3	no	15.913	15.900	EPSD	COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P00533	EGFR	P27361	MAPK3	S752	S752P	752	Missense	central	0	yes	15.913	0.000	EPSD	COSMIC	9.358	Loss
CMGC_MAPK_ERK1_MAPK3_ST	P00533	EGFR	P27361	MAPK3	S752	E758D	758	Missense	distal	6	no	15.913	15.868	EPSD	COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P00533	EGFR	P27361	MAPK3	S752	K745T	745	Missense	distal	-7	no	15.913	15.905	EPSD	COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P00533	EGFR	P27361	MAPK3	S752	E746K	746	Missense	distal	-6	no	15.913	15.771	EPSD	COSMIC;GDSC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P00533	EGFR	P27361	MAPK3	S752	A755V	755	Missense	distal	3	no	15.913	15.919	EPSD	COSMIC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P00533	EGFR	P27361	MAPK3	S752	L747V	747	Missense	distal	-5	no	15.913	15.896	EPSD	COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P00533	EGFR	P27361	MAPK3	S752	T751P	751	Missense	proximal	-1	no	15.913	15.949	EPSD	COSMIC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P00533	EGFR	P27361	MAPK3	S752	R748I	748	Missense	distal	-4	no	15.913	15.830	EPSD	COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P00533	EGFR	P27361	MAPK3	S752	K757M	757	Missense	distal	5	no	15.913	15.674	EPSD	COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P00533	EGFR	P27361	MAPK3	S752	P753F	753	Missense	proximal	1	no	15.913	9.699	EPSD	COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P00533	EGFR	P27361	MAPK3	S991	F997L	997	Missense	distal	6	no	16.779	17.136	EPSD	COSMIC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P00533	EGFR	P27361	MAPK3	S991	D984N	984	Missense	distal	-7	no	16.779	16.804	EPSD	COSMIC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P00533	EGFR	P27361	MAPK3	S991	M987R	987	Missense	distal	-4	no	16.779	16.882	EPSD	COSMIC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P00533	EGFR	P27361	MAPK3	S1026	S1025T	1025	Missense	proximal	-1	no	16.359	16.329	EPSD	COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P00533	EGFR	P27361	MAPK3	S1026	P1027S	1027	Missense	proximal	1	no	16.359	7.306	EPSD	COSMIC	9.358	Loss
CMGC_MAPK_ERK1_MAPK3_ST	P00533	EGFR	P27361	MAPK3	S1026	P1019S	1019	Missense	distal	-7	no	16.359	16.322	EPSD	COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P00533	EGFR	P27361	MAPK3	S1026	G1022S	1022	Missense	distal	-4	no	16.359	16.398	EPSD	COSMIC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P00533	EGFR	P27361	MAPK3	S1026	S1028L	1028	Missense	proximal	2	no	16.359	16.336	EPSD	COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P00533	EGFR	P27361	MAPK3	S1026	Q1020H	1020	Missense	distal	-6	no	16.359	16.345	EPSD	COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P00533	EGFR	P27361	MAPK3	S1028	S1025T	1025	Missense	distal	-3	no	9.954	9.923	EPSD	COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P00533	EGFR	P27361	MAPK3	S1028	P1027S	1027	Missense	proximal	-1	no	9.954	9.948	EPSD	COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P00533	EGFR	P27361	MAPK3	S1028	G1022S	1022	Missense	distal	-6	no	9.954	10.016	EPSD	COSMIC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P00533	EGFR	P27361	MAPK3	S1028	S1028L	1028	Missense	central	0	yes	9.954	0.000	EPSD	COSMIC	9.358	Loss
CMGC_MAPK_ERK1_MAPK3_ST	P00533	EGFR	P27361	MAPK3	S1028	L1034I	1034	Missense	distal	6	no	9.954	9.741	EPSD	COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P00533	EGFR	P27361	MAPK3	T1032	S1025T	1025	Missense	distal	-7	no	13.788	13.864	EPSD	COSMIC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P00533	EGFR	P27361	MAPK3	T1032	P1027S	1027	Missense	distal	-5	no	13.788	13.793	EPSD	COSMIC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P00533	EGFR	P27361	MAPK3	T1032	S1036R	1036	Missense	distal	4	no	13.788	13.641	EPSD	COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P00533	EGFR	P27361	MAPK3	T1032	S1028L	1028	Missense	distal	-4	no	13.788	13.647	EPSD	COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P00533	EGFR	P27361	MAPK3	T1032	L1034I	1034	Missense	proximal	2	no	13.788	13.776	EPSD	COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P00533	EGFR	P27361	MAPK3	S1057	C1058Y	1058	Missense	proximal	1	no	1.858	10.117	EPSD	COSMIC	9.358	Gain
CMGC_MAPK_ERK1_MAPK3_ST	P00533	EGFR	P27361	MAPK3	S1064	C1058Y	1058	Missense	distal	-6	no	9.176	9.482	EPSD	COSMIC	9.358	Gain
CMGC_MAPK_ERK1_MAPK3_ST	P00533	EGFR	P27361	MAPK3	S1064	S1071L	1071	Missense	distal	7	no	9.176	9.446	EPSD	COSMIC	9.358	Gain
CMGC_MAPK_ERK1_MAPK3_ST	P00533	EGFR	P27361	MAPK3	T1085	D1084G	1084	Missense	proximal	-1	no	10.911	10.892	EPSD	COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P00533	EGFR	P27361	MAPK3	T1085	D1083G	1083	Missense	proximal	-2	no	10.911	10.402	EPSD	COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P00533	EGFR	P27361	MAPK3	T1085	P1088S	1088	Missense	distal	3	no	10.911	10.906	EPSD	COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P00533	EGFR	P27361	MAPK3	S1153	A1155D	1155	Missense	proximal	2	no	15.338	15.365	EPSD	COSMIC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P00533	EGFR	P27361	MAPK3	S1153	V1147I	1147	Missense	distal	-6	no	15.338	15.269	EPSD	COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P00533	EGFR	P27361	MAPK3	S1153	Q1159H	1159	Missense	distal	6	no	15.338	15.426	EPSD	COSMIC;GDSC;CCLE	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P00533	EGFR	P27361	MAPK3	S1153	A1158P	1158	Missense	distal	5	no	15.338	15.550	EPSD	COSMIC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P00533	EGFR	P27361	MAPK3	S1153	D1152H	1152	Missense	proximal	-1	no	15.338	15.345	EPSD	COSMIC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P00533	EGFR	P27361	MAPK3	S1190	K1188T	1188	Missense	proximal	-2	no	8.240	9.595	EPSD	COSMIC	9.358	Gain
CMGC_MAPK_ERK1_MAPK3_ST	P00533	EGFR	P27361	MAPK3	S1204	R1199M	1199	Missense	distal	-5	no	11.806	11.733	EPSD	COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P00533	EGFR	P27361	MAPK3	S1204	S1204R	1204	Missense	central	0	yes	11.806	0.000	EPSD	COSMIC	9.358	Loss
CMGC_MAPK_ERK1_MAPK3_ST	P00533	EGFR	P27361	MAPK3	S1204	A1201T	1201	Missense	distal	-3	no	11.806	11.868	EPSD	COSMIC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P00533	EGFR	P27361	MAPK3	S1204	F1207C	1207	Missense	distal	3	no	11.806	11.785	EPSD	COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P00533	EGFR	P27361	MAPK3	S1204	R1199T	1199	Missense	distal	-5	no	11.806	11.836	EPSD	COSMIC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P00533	EGFR	P27361	MAPK3	S1204	V1200I	1200	Missense	distal	-4	no	11.806	11.799	EPSD	COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P00533	EGFR	P27361	MAPK3	S1205	R1199M	1199	Missense	distal	-6	no	10.816	10.555	EPSD	COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P00533	EGFR	P27361	MAPK3	S1205	S1204R	1204	Missense	proximal	-1	no	10.816	10.775	EPSD	COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P00533	EGFR	P27361	MAPK3	S1205	A1201T	1201	Missense	distal	-4	no	10.816	10.890	EPSD	COSMIC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P00533	EGFR	P27361	MAPK3	S1205	F1207C	1207	Missense	proximal	2	no	10.816	10.805	EPSD	COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P00533	EGFR	P27361	MAPK3	S1205	R1199T	1199	Missense	distal	-6	no	10.816	10.808	EPSD	COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P00533	EGFR	P27361	MAPK3	S1205	V1200I	1200	Missense	distal	-5	no	10.816	10.798	EPSD	COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P63000	RAC1	P27361	MAPK3	S71	L67I	67	Missense	distal	-4	no	11.073	11.054	EPSD	COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P63000	RAC1	P27361	MAPK3	S71	D65Y	65	Missense	distal	-6	no	11.073	10.880	EPSD	COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P63000	RAC1	P27361	MAPK3	S71	P69L	69	Missense	proximal	-2	no	11.073	9.689	EPSD	COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P63000	RAC1	P27361	MAPK3	S71	D65N	65	Missense	distal	-6	no	11.073	11.011	EPSD	COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P63000	RAC1	P27361	MAPK3	S89	N92I	92	Missense	distal	3	no	12.292	12.261	EPSD	COSMIC;CCLE	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P63000	RAC1	P27361	MAPK3	S89	S89L	89	Missense	central	0	yes	12.292	0.000	EPSD	COSMIC	9.358	Loss
CMGC_MAPK_ERK1_MAPK3_ST	P63000	RAC1	P27361	MAPK3	S89	N92S	92	Missense	distal	3	no	12.292	12.313	EPSD	COSMIC;CCLE	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P63000	RAC1	P27361	MAPK3	S89	E91Q	91	Missense	proximal	2	no	12.292	12.279	EPSD	COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P63000	RAC1	P27361	MAPK3	S89	S86F	86	Missense	distal	-3	no	12.292	12.150	EPSD	COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P63000	RAC1	P27361	MAPK3	T108	T115A	115	Missense	distal	7	no	16.930	17.158	PhosphoSitePlus	COSMIC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P63000	RAC1	P27361	MAPK3	T108	V113L	113	Missense	distal	5	no	16.930	16.926	PhosphoSitePlus	COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	O60244	MED14	P27361	MAPK3	S120	A126D	126	Missense	distal	6	no	9.266	9.615	EPSD	COSMIC	9.358	Gain
CMGC_MAPK_ERK1_MAPK3_ST	O60244	MED14	P27361	MAPK3	S151	A153V	153	Missense	proximal	2	no	10.021	10.034	EPSD	COSMIC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	O60244	MED14	P27361	MAPK3	S986	P984S	984	Missense	proximal	-2	no	17.048	15.972	PhosphoSitePlus	COSMIC;GDSC;CCLE	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	O60244	MED14	P27361	MAPK3	S986	N979H	979	Missense	distal	-7	no	17.048	17.052	PhosphoSitePlus	COSMIC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	O60244	MED14	P27361	MAPK3	S1061	S1054R	1054	Missense	distal	-7	no	13.717	13.800	EPSD	COSMIC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	O60244	MED14	P27361	MAPK3	S1086	A1082V	1082	Missense	distal	-4	no	15.169	15.149	EPSD	COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	O60244	MED14	P27361	MAPK3	S1086	G1079V	1079	Missense	distal	-7	no	15.169	15.280	EPSD	COSMIC;GDSC;CCLE	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	O60244	MED14	P27361	MAPK3	S1112	S1116F	1116	Missense	distal	4	no	16.484	16.070	EPSD	COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	O60244	MED14	P27361	MAPK3	S1119	S1116F	1116	Missense	distal	-3	no	14.917	14.776	EPSD	COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	O60244	MED14	P27361	MAPK3	S1119	R1123C	1123	Missense	distal	4	no	14.917	14.560	EPSD	COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	O60244	MED14	P27361	MAPK3	S1128	R1123C	1123	Missense	distal	-5	no	16.417	16.301	EPSD	COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	O60244	MED14	P27361	MAPK3	S1136	P1139S	1139	Missense	distal	3	no	16.122	16.117	EPSD	COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	O60244	MED14	P27361	MAPK3	S1144	P1139S	1139	Missense	distal	-5	no	16.725	16.730	EPSD	COSMIC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	O60244	MED14	P27361	MAPK3	S1144	R1146Q	1146	Missense	proximal	2	no	16.725	16.715	EPSD	COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	O60244	MED14	P27361	MAPK3	S1151	R1146Q	1146	Missense	distal	-5	no	9.953	9.945	EPSD	COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	O60244	MED14	P27361	MAPK3	S1254	N1258Y	1258	Missense	distal	4	no	15.993	15.924	EPSD	COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	O60244	MED14	P27361	MAPK3	S1254	K1248Q	1248	Missense	distal	-6	no	15.993	16.001	EPSD	COSMIC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P61978	HNRNPK	P27361	MAPK3	S75	N73D	73	Missense	proximal	-2	no	9.027	9.440	EPSD	COSMIC	9.358	Gain
CMGC_MAPK_ERK1_MAPK3_ST	P61978	HNRNPK	P27361	MAPK3	S116	L123P	123	Missense	distal	7	no	16.938	16.746	EPSD	COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P61978	HNRNPK	P27361	MAPK3	S116	T118A	118	Missense	proximal	2	no	16.938	16.911	EPSD	COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P61978	HNRNPK	P27361	MAPK3	S284	M283T	283	Missense	proximal	-1	no	16.461	16.586	PhosphoSitePlus;EPSD	COSMIC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P61978	HNRNPK	P27361	MAPK3	S379	G376D	376	Missense	distal	-3	no	10.614	10.624	EPSD	COSMIC;CCLE	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P61978	HNRNPK	P27361	MAPK3	S379	S372A	372	Missense	distal	-7	no	10.614	10.764	EPSD	COSMIC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P61978	HNRNPK	P27361	MAPK3	T440	R433W	433	Missense	distal	-7	no	11.582	11.828	EPSD	COSMIC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P61978	HNRNPK	P27361	MAPK3	T440	I435V	435	Missense	distal	-5	no	11.582	11.601	EPSD	COSMIC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P61978	HNRNPK	P27361	MAPK3	T440	I435T	435	Missense	distal	-5	no	11.582	11.661	EPSD	COSMIC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P29966	MARCKS	P27361	MAPK3	S118	A122T	122	Missense	distal	4	no	17.485	17.703	EPSD	COSMIC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P29966	MARCKS	P27361	MAPK3	S118	T120M	120	Missense	proximal	2	no	17.485	17.453	EPSD	COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P29966	MARCKS	P27361	MAPK3	S135	S131A	131	Missense	distal	-4	no	17.009	16.877	EPSD	COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P29966	MARCKS	P27361	MAPK3	S135	A142P	142	Missense	distal	7	no	17.009	16.741	EPSD	COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P29966	MARCKS	P27361	MAPK3	T143	A142P	142	Missense	proximal	-1	no	13.202	13.342	EPSD	COSMIC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P29966	MARCKS	P27361	MAPK3	S145	A142P	142	Missense	distal	-3	no	16.801	16.901	EPSD	COSMIC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	O43524	FOXO3	P27361	MAPK3	S7	A2V	2	Missense	distal	-5	no	16.050	16.073	EPSD	COSMIC;CCLE	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	O43524	FOXO3	P27361	MAPK3	S7	A6S	6	Missense	proximal	-1	no	16.050	16.183	EPSD	COSMIC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	O43524	FOXO3	P27361	MAPK3	S12	A6S	6	Missense	distal	-6	no	18.980	19.296	EPSD;PhosphoSitePlus	COSMIC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	O43524	FOXO3	P27361	MAPK3	S26	R29L	29	Missense	distal	3	no	11.724	11.714	EPSD	COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	O43524	FOXO3	P27361	MAPK3	S43	E50D	50	Missense	distal	7	no	14.611	14.613	EPSD	COSMIC;CCLE	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	O43524	FOXO3	P27361	MAPK3	S161	R154Q	154	Missense	distal	-7	no	10.249	10.248	EPSD	COSMIC;GDSC;CCLE	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	O43524	FOXO3	P27361	MAPK3	S294	P295L	295	Missense	proximal	1	no	18.649	9.611	PhosphoSitePlus;EPSD	COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	O43524	FOXO3	P27361	MAPK3	S299	P295L	295	Missense	distal	-4	no	9.609	9.496	EPSD	COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	O43524	FOXO3	P27361	MAPK3	S325	S318C	318	Missense	distal	-7	no	15.988	16.258	EPSD	COSMIC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	O43524	FOXO3	P27361	MAPK3	S325	R323C	323	Missense	proximal	-2	no	15.988	13.872	EPSD	COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	O43524	FOXO3	P27361	MAPK3	S325	E332Q	332	Missense	distal	7	no	15.988	16.083	EPSD	COSMIC;CCLE	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	O43524	FOXO3	P27361	MAPK3	S325	R323H	323	Missense	proximal	-2	no	15.988	16.161	EPSD	COSMIC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	O43524	FOXO3	P27361	MAPK3	S344	A341T	341	Missense	distal	-3	no	17.722	17.783	EPSD;PhosphoSitePlus	COSMIC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	O43524	FOXO3	P27361	MAPK3	S355	P361L	361	Missense	distal	6	no	16.937	16.710	EPSD	COSMIC;GDSC;CCLE	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	O43524	FOXO3	P27361	MAPK3	S402	P397R	397	Missense	distal	-5	no	15.143	15.103	EPSD	COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	O43524	FOXO3	P27361	MAPK3	S413	F414Y	414	Missense	proximal	1	no	9.925	9.090	EPSD	COSMIC	9.358	Loss
CMGC_MAPK_ERK1_MAPK3_ST	O43524	FOXO3	P27361	MAPK3	S425	G424V	424	Missense	proximal	-1	no	16.864	16.846	EPSD;PhosphoSitePlus	COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	O43524	FOXO3	P27361	MAPK3	S429	G424V	424	Missense	distal	-5	no	10.656	10.623	EPSD	COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q13115	DUSP4	P27361	MAPK3	S112	S112N	112	Missense	central	0	yes	17.462	0.000	EPSD	COSMIC	9.358	Loss
CMGC_MAPK_ERK1_MAPK3_ST	Q13115	DUSP4	P27361	MAPK3	T188	G187R	187	Missense	proximal	-1	no	11.851	11.875	EPSD	COSMIC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q13115	DUSP4	P27361	MAPK3	S345	S345I	345	Missense	central	0	yes	15.420	0.000	EPSD	COSMIC;GDSC	9.358	Loss
CMGC_MAPK_ERK1_MAPK3_ST	Q13115	DUSP4	P27361	MAPK3	T356	T361S	361	Missense	distal	5	no	13.385	13.521	EPSD	COSMIC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q13115	DUSP4	P27361	MAPK3	T359	T361S	361	Missense	proximal	2	no	16.806	16.818	EPSD	COSMIC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q13115	DUSP4	P27361	MAPK3	S367	T361S	361	Missense	distal	-6	no	11.751	11.920	EPSD	COSMIC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q13115	DUSP4	P27361	MAPK3	S371	S376L	376	Missense	distal	5	no	10.009	9.738	EPSD	COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q13115	DUSP4	P27361	MAPK3	S376	S380C	380	Missense	distal	4	no	9.397	8.894	EPSD	COSMIC	9.358	Loss
CMGC_MAPK_ERK1_MAPK3_ST	Q13115	DUSP4	P27361	MAPK3	S376	S376L	376	Missense	central	0	yes	9.397	0.000	EPSD	COSMIC	9.358	Loss
CMGC_MAPK_ERK1_MAPK3_ST	Q13115	DUSP4	P27361	MAPK3	S380	S380C	380	Missense	central	0	yes	10.090	0.000	EPSD	COSMIC	9.358	Loss
CMGC_MAPK_ERK1_MAPK3_ST	Q13115	DUSP4	P27361	MAPK3	S380	S376L	376	Missense	distal	-4	no	10.090	9.949	EPSD	COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q13115	DUSP4	P27361	MAPK3	S386	S380C	380	Missense	distal	-6	no	18.530	17.971	EPSD;PhosphoSitePlus	COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q9UHB6	LIMA1	P27361	MAPK3	S4	R9S	9	Missense	distal	5	no	16.033	16.177	EPSD	COSMIC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q9UHB6	LIMA1	P27361	MAPK3	S4	R9M	9	Missense	distal	5	no	16.033	15.786	EPSD	COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q9UHB6	LIMA1	P27361	MAPK3	S218	A219P	219	Missense	proximal	1	no	6.285	15.525	EPSD	COSMIC	9.358	Gain
CMGC_MAPK_ERK1_MAPK3_ST	Q9UHB6	LIMA1	P27361	MAPK3	T265	S266F	266	Missense	proximal	1	no	8.017	10.856	EPSD	COSMIC	9.358	Gain
CMGC_MAPK_ERK1_MAPK3_ST	Q9UHB6	LIMA1	P27361	MAPK3	T265	S266P	266	Missense	proximal	1	no	8.017	17.070	EPSD	COSMIC	9.358	Gain
CMGC_MAPK_ERK1_MAPK3_ST	Q9UHB6	LIMA1	P27361	MAPK3	T337	P338T	338	Missense	proximal	1	no	14.391	5.514	EPSD	COSMIC	9.358	Loss
CMGC_MAPK_ERK1_MAPK3_ST	Q9UHB6	LIMA1	P27361	MAPK3	T337	R335S	335	Missense	proximal	-2	no	14.391	14.715	EPSD	COSMIC;CCLE	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q9UHB6	LIMA1	P27361	MAPK3	S362	L361P	361	Missense	proximal	-1	no	17.888	17.982	EPSD;PhosphoSitePlus	COSMIC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q9UHB6	LIMA1	P27361	MAPK3	S362	S365F	365	Missense	distal	3	no	17.888	17.823	EPSD;PhosphoSitePlus	COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q9UHB6	LIMA1	P27361	MAPK3	S362	S369G	369	Missense	distal	7	no	17.888	18.027	EPSD;PhosphoSitePlus	COSMIC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q9UHB6	LIMA1	P27361	MAPK3	S362	P360S	360	Missense	proximal	-2	no	17.888	16.812	EPSD;PhosphoSitePlus	COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q9UHB6	LIMA1	P27361	MAPK3	S374	S373N	373	Missense	proximal	-1	no	16.594	16.545	PhosphoSitePlus;EPSD	COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q9UHB6	LIMA1	P27361	MAPK3	S374	P376I	376	Missense	proximal	2	no	16.594	16.560	PhosphoSitePlus;EPSD	COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q9UHB6	LIMA1	P27361	MAPK3	S374	P376L	376	Missense	proximal	2	no	16.594	16.572	PhosphoSitePlus;EPSD	COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q9UHB6	LIMA1	P27361	MAPK3	S374	P376T	376	Missense	proximal	2	no	16.594	16.584	PhosphoSitePlus;EPSD	COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q9UHB6	LIMA1	P27361	MAPK3	S374	S369G	369	Missense	distal	-5	no	16.594	16.550	PhosphoSitePlus;EPSD	COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q9UHB6	LIMA1	P27361	MAPK3	S374	L370V	370	Missense	distal	-4	no	16.594	16.582	PhosphoSitePlus;EPSD	COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q9UHB6	LIMA1	P27361	MAPK3	S374	A378P	378	Missense	distal	4	no	16.594	16.876	PhosphoSitePlus;EPSD	COSMIC;CCLE	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q9UHB6	LIMA1	P27361	MAPK3	S490	A496T	496	Missense	distal	6	no	17.216	17.586	EPSD	COSMIC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q9UHB6	LIMA1	P27361	MAPK3	S490	A496V	496	Missense	distal	6	no	17.216	17.303	EPSD	COSMIC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q9UHB6	LIMA1	P27361	MAPK3	S490	P497S	497	Missense	distal	7	no	17.216	17.138	EPSD	COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q9UHB6	LIMA1	P27361	MAPK3	S581	S582F	582	Missense	proximal	1	no	8.500	11.340	EPSD	COSMIC	9.358	Gain
CMGC_MAPK_ERK1_MAPK3_ST	Q9UHB6	LIMA1	P27361	MAPK3	S596	S601F	601	Missense	distal	5	no	9.672	9.248	EPSD	COSMIC	9.358	Loss
CMGC_MAPK_ERK1_MAPK3_ST	Q9UHB6	LIMA1	P27361	MAPK3	S596	F591L	591	Missense	distal	-5	no	9.672	9.747	EPSD	COSMIC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q9UHB6	LIMA1	P27361	MAPK3	S596	S601Y	601	Missense	distal	5	no	9.672	9.456	EPSD	COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q9UHB6	LIMA1	P27361	MAPK3	S596	R589H	589	Missense	distal	-7	no	9.672	9.661	EPSD	COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q9UHB6	LIMA1	P27361	MAPK3	S596	Q598E	598	Missense	proximal	2	no	9.672	9.685	EPSD	COSMIC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q9UHB6	LIMA1	P27361	MAPK3	S596	R589I	589	Missense	distal	-7	no	9.672	9.781	EPSD	COSMIC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q9UHB6	LIMA1	P27361	MAPK3	S596	R589W	589	Missense	distal	-7	no	9.672	9.918	EPSD	COSMIC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q9UHB6	LIMA1	P27361	MAPK3	S604	S601F	601	Missense	distal	-3	no	16.043	15.902	EPSD;PhosphoSitePlus	COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q9UHB6	LIMA1	P27361	MAPK3	S604	V608M	608	Missense	distal	4	no	16.043	15.888	EPSD;PhosphoSitePlus	COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q9UHB6	LIMA1	P27361	MAPK3	S604	S601Y	601	Missense	distal	-3	no	16.043	15.980	EPSD;PhosphoSitePlus	COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q9UHB6	LIMA1	P27361	MAPK3	S604	Q598E	598	Missense	distal	-6	no	16.043	16.178	EPSD;PhosphoSitePlus	COSMIC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q9UHB6	LIMA1	P27361	MAPK3	S609	V608M	608	Missense	proximal	-1	no	16.753	16.682	EPSD	COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q9UHB6	LIMA1	P27361	MAPK3	S619	S625F	625	Missense	distal	6	no	9.465	8.752	EPSD	COSMIC	9.358	Loss
CMGC_MAPK_ERK1_MAPK3_ST	Q9UHB6	LIMA1	P27361	MAPK3	S619	S617N	617	Missense	proximal	-2	no	9.465	8.521	EPSD	COSMIC	9.358	Loss
CMGC_MAPK_ERK1_MAPK3_ST	Q9UHB6	LIMA1	P27361	MAPK3	S686	A684T	684	Missense	proximal	-2	no	8.242	9.607	EPSD	COSMIC	9.358	Gain
CMGC_MAPK_ERK1_MAPK3_ST	Q9UHB6	LIMA1	P27361	MAPK3	S692	D687N	687	Missense	distal	-5	no	10.352	10.347	EPSD	COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q9UHB6	LIMA1	P27361	MAPK3	S692	E688V	688	Missense	distal	-4	no	10.352	10.225	EPSD	COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q9UHB6	LIMA1	P27361	MAPK3	S692	D690H	690	Missense	proximal	-2	no	10.352	10.732	EPSD	COSMIC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q9UHB6	LIMA1	P27361	MAPK3	S698	Q700H	700	Missense	proximal	2	no	15.761	15.768	EPSD	COSMIC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q9UHB6	LIMA1	P27361	MAPK3	S704	N706I	706	Missense	proximal	2	no	10.127	10.109	EPSD	COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q9UHB6	LIMA1	P27361	MAPK3	S704	Q700H	700	Missense	distal	-4	no	10.127	10.131	EPSD	COSMIC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q9UHB6	LIMA1	P27361	MAPK3	S704	V711A	711	Missense	distal	7	no	10.127	10.155	EPSD	COSMIC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q9UHB6	LIMA1	P27361	MAPK3	S704	S709C	709	Missense	distal	5	no	10.127	9.604	EPSD	COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P24941	CDK2	P27361	MAPK3	T221	R217W	217	Missense	distal	-4	no	17.340	17.132	EPSD	COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P24941	CDK2	P27361	MAPK3	T221	R217L	217	Missense	distal	-4	no	17.340	17.277	EPSD	COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P24941	CDK2	P27361	MAPK3	T221	V226M	226	Missense	distal	5	no	17.340	17.215	EPSD	COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P24941	CDK2	P27361	MAPK3	T221	R214W	214	Missense	distal	-7	no	17.340	17.586	EPSD	COSMIC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q05209	PTPN12	P27361	MAPK3	S19	D26A	26	Missense	distal	7	no	15.619	15.858	EPSD	COSMIC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q05209	PTPN12	P27361	MAPK3	S186	R187P	187	Missense	proximal	1	no	7.172	16.672	EPSD	COSMIC	9.358	Gain
CMGC_MAPK_ERK1_MAPK3_ST	Q05209	PTPN12	P27361	MAPK3	S332	E326D	326	Missense	distal	-6	no	17.090	17.046	EPSD	COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q05209	PTPN12	P27361	MAPK3	S332	E326G	326	Missense	distal	-6	no	17.090	17.045	EPSD	COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q05209	PTPN12	P27361	MAPK3	S332	P335S	335	Missense	distal	3	no	17.090	17.086	EPSD	COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q05209	PTPN12	P27361	MAPK3	T367	L366V	366	Missense	proximal	-1	no	13.676	13.681	EPSD	COSMIC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q05209	PTPN12	P27361	MAPK3	T367	P370S	370	Missense	distal	3	no	13.676	13.672	EPSD	COSMIC;GDSC;CCLE	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q05209	PTPN12	P27361	MAPK3	T367	P361L	361	Missense	distal	-6	no	13.676	13.429	EPSD	COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q05209	PTPN12	P27361	MAPK3	S369	L366V	366	Missense	distal	-3	no	15.786	15.789	EPSD	COSMIC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q05209	PTPN12	P27361	MAPK3	S369	P370S	370	Missense	proximal	1	no	15.786	6.732	EPSD	COSMIC;GDSC;CCLE	9.358	Loss
CMGC_MAPK_ERK1_MAPK3_ST	Q05209	PTPN12	P27361	MAPK3	S449	T454A	454	Missense	distal	5	no	9.846	9.727	EPSD	COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q05209	PTPN12	P27361	MAPK3	S449	T454I	454	Missense	distal	5	no	9.846	9.589	EPSD	COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q05209	PTPN12	P27361	MAPK3	S449	D451N	451	Missense	proximal	2	no	9.846	9.841	EPSD	COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q05209	PTPN12	P27361	MAPK3	S449	E445G	445	Missense	distal	-4	no	9.846	9.832	EPSD	COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q05209	PTPN12	P27361	MAPK3	S449	E445D	445	Missense	distal	-4	no	9.846	9.835	EPSD	COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q05209	PTPN12	P27361	MAPK3	S468	I462N	462	Missense	distal	-6	no	17.703	17.979	EPSD	COSMIC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q05209	PTPN12	P27361	MAPK3	S468	K463I	463	Missense	distal	-5	no	17.703	17.655	EPSD	COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q05209	PTPN12	P27361	MAPK3	S468	K474N	474	Missense	distal	6	no	17.703	17.682	EPSD	COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q05209	PTPN12	P27361	MAPK3	S468	I471V	471	Missense	distal	3	no	17.703	17.717	EPSD	COSMIC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q05209	PTPN12	P27361	MAPK3	T509	P511Q	511	Missense	proximal	2	no	15.251	15.231	EPSD	COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q05209	PTPN12	P27361	MAPK3	S537	W536R	536	Missense	proximal	-1	no	10.914	11.152	EPSD	COSMIC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q05209	PTPN12	P27361	MAPK3	S537	T535M	535	Missense	proximal	-2	no	10.914	9.146	EPSD	COSMIC	9.358	Loss
CMGC_MAPK_ERK1_MAPK3_ST	Q05209	PTPN12	P27361	MAPK3	T569	T574A	574	Missense	distal	5	no	16.217	16.098	EPSD	COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q05209	PTPN12	P27361	MAPK3	T569	T574I	574	Missense	distal	5	no	16.217	15.960	EPSD	COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q05209	PTPN12	P27361	MAPK3	T569	T574P	574	Missense	distal	5	no	16.217	16.310	EPSD	COSMIC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q05209	PTPN12	P27361	MAPK3	T569	T574S	574	Missense	distal	5	no	16.217	16.353	EPSD	COSMIC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q05209	PTPN12	P27361	MAPK3	T569	T573A	573	Missense	distal	4	no	16.217	15.999	EPSD	COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q05209	PTPN12	P27361	MAPK3	S571	T574A	574	Missense	distal	3	no	16.653	16.622	PhosphoSitePlus	COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q05209	PTPN12	P27361	MAPK3	S571	T574I	574	Missense	distal	3	no	16.653	16.615	PhosphoSitePlus	COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q05209	PTPN12	P27361	MAPK3	S571	T574P	574	Missense	distal	3	no	16.653	16.671	PhosphoSitePlus	COSMIC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q05209	PTPN12	P27361	MAPK3	S571	T574S	574	Missense	distal	3	no	16.653	16.666	PhosphoSitePlus	COSMIC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q05209	PTPN12	P27361	MAPK3	S571	T573A	573	Missense	proximal	2	no	16.653	16.625	PhosphoSitePlus	COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q05209	PTPN12	P27361	MAPK3	T573	T574P	574	Missense	proximal	1	no	5.274	14.151	EPSD	COSMIC	9.358	Gain
CMGC_MAPK_ERK1_MAPK3_ST	Q05209	PTPN12	P27361	MAPK3	T578	T574A	574	Missense	distal	-4	no	13.705	13.632	EPSD	COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q05209	PTPN12	P27361	MAPK3	T578	T574I	574	Missense	distal	-4	no	13.705	13.604	EPSD	COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q05209	PTPN12	P27361	MAPK3	T578	T574P	574	Missense	distal	-4	no	13.705	13.736	EPSD	COSMIC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q05209	PTPN12	P27361	MAPK3	T578	T574S	574	Missense	distal	-4	no	13.705	13.763	EPSD	COSMIC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q05209	PTPN12	P27361	MAPK3	T578	T573A	573	Missense	distal	-5	no	13.705	13.622	EPSD	COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q05209	PTPN12	P27361	MAPK3	T578	D585G	585	Missense	distal	7	no	13.705	13.738	EPSD	COSMIC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q05209	PTPN12	P27361	MAPK3	T578	L581I	581	Missense	distal	3	no	13.705	13.686	EPSD	COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q05209	PTPN12	P27361	MAPK3	S588	L590I	590	Missense	proximal	2	no	16.520	16.509	EPSD	COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q05209	PTPN12	P27361	MAPK3	S588	D585G	585	Missense	distal	-3	no	16.520	16.511	EPSD	COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q05209	PTPN12	P27361	MAPK3	S588	L581I	581	Missense	distal	-7	no	16.520	16.567	EPSD	COSMIC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q05209	PTPN12	P27361	MAPK3	T593	L590I	590	Missense	distal	-3	no	14.354	14.318	EPSD	COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q05209	PTPN12	P27361	MAPK3	S596	L590I	590	Missense	distal	-6	no	10.282	10.215	EPSD	COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q05209	PTPN12	P27361	MAPK3	S673	P676H	676	Missense	distal	3	no	15.757	15.738	EPSD	COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q05209	PTPN12	P27361	MAPK3	S673	R680K	680	Missense	distal	7	no	15.757	15.763	EPSD	COSMIC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q05209	PTPN12	P27361	MAPK3	S673	P678R	678	Missense	distal	5	no	15.757	15.657	EPSD	COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q05209	PTPN12	P27361	MAPK3	T681	P676H	676	Missense	distal	-5	no	13.665	13.634	EPSD	COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q05209	PTPN12	P27361	MAPK3	T681	R680K	680	Missense	proximal	-1	no	13.665	13.651	EPSD	COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q05209	PTPN12	P27361	MAPK3	T681	A688V	688	Missense	distal	7	no	13.665	13.637	EPSD	COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q05209	PTPN12	P27361	MAPK3	T681	P678R	678	Missense	distal	-3	no	13.665	13.618	EPSD	COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q05209	PTPN12	P27361	MAPK3	S684	R680K	680	Missense	distal	-4	no	12.824	12.817	EPSD	COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q05209	PTPN12	P27361	MAPK3	S684	A688V	688	Missense	distal	4	no	12.824	12.932	EPSD	COSMIC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q05209	PTPN12	P27361	MAPK3	S684	P678R	678	Missense	distal	-6	no	12.824	12.748	EPSD	COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q05209	PTPN12	P27361	MAPK3	T693	S697T	697	Missense	distal	4	no	14.867	14.754	EPSD	COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q05209	PTPN12	P27361	MAPK3	T693	E698Q	698	Missense	distal	5	no	14.867	14.745	EPSD	COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q05209	PTPN12	P27361	MAPK3	T693	W699L	699	Missense	distal	6	no	14.867	15.575	EPSD	COSMIC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q05209	PTPN12	P27361	MAPK3	T693	T693P	693	Missense	central	0	yes	14.867	0.000	EPSD	COSMIC	9.358	Loss
CMGC_MAPK_ERK1_MAPK3_ST	Q05209	PTPN12	P27361	MAPK3	T693	A688V	688	Missense	distal	-5	no	14.867	14.890	EPSD	COSMIC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q05209	PTPN12	P27361	MAPK3	T693	P694H	694	Missense	proximal	1	no	14.867	7.111	EPSD	COSMIC	9.358	Loss
CMGC_MAPK_ERK1_MAPK3_ST	Q05209	PTPN12	P27361	MAPK3	T693	T693A	693	Missense	central	0	yes	14.867	0.000	EPSD	COSMIC	9.358	Loss
CMGC_MAPK_ERK1_MAPK3_ST	Q05209	PTPN12	P27361	MAPK3	T693	T693I	693	Missense	central	0	yes	14.867	0.000	EPSD	COSMIC	9.358	Loss
CMGC_MAPK_ERK1_MAPK3_ST	Q05209	PTPN12	P27361	MAPK3	T693	N692K	692	Missense	proximal	-1	no	14.867	14.860	EPSD	COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q96Q27	ASB2	P27361	MAPK3	S28	P25S	25	Missense	distal	-3	no	10.955	10.947	EPSD	COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q96Q27	ASB2	P27361	MAPK3	S28	S29L	29	Missense	proximal	1	no	10.955	10.971	EPSD	COSMIC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q96Q27	ASB2	P27361	MAPK3	S28	R21S	21	Missense	distal	-7	no	10.955	10.872	EPSD	COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q96Q27	ASB2	P27361	MAPK3	S28	R32W	32	Missense	distal	4	no	10.955	10.488	EPSD	COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q96Q27	ASB2	P27361	MAPK3	S28	R32Q	32	Missense	distal	4	no	10.955	10.911	EPSD	COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q96Q27	ASB2	P27361	MAPK3	S28	M35I	35	Missense	distal	7	no	10.955	10.903	EPSD	COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q96Q27	ASB2	P27361	MAPK3	S28	E27Q	27	Missense	proximal	-1	no	10.955	10.899	EPSD	COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q96Q27	ASB2	P27361	MAPK3	S28	M35V	35	Missense	distal	7	no	10.955	10.823	EPSD	COSMIC;GDSC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q96Q27	ASB2	P27361	MAPK3	S29	P25S	25	Missense	distal	-4	no	17.534	17.561	EPSD	COSMIC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q96Q27	ASB2	P27361	MAPK3	S29	S29L	29	Missense	central	0	yes	17.534	0.000	EPSD	COSMIC	9.358	Loss
CMGC_MAPK_ERK1_MAPK3_ST	Q96Q27	ASB2	P27361	MAPK3	S29	R32W	32	Missense	distal	3	no	17.534	17.456	EPSD	COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q96Q27	ASB2	P27361	MAPK3	S29	M35I	35	Missense	distal	6	no	17.534	17.613	EPSD	COSMIC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q96Q27	ASB2	P27361	MAPK3	S29	E27Q	27	Missense	proximal	-2	no	17.534	17.416	EPSD	COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q96Q27	ASB2	P27361	MAPK3	S29	M35V	35	Missense	distal	6	no	17.534	17.744	EPSD	COSMIC;GDSC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q96Q27	ASB2	P27361	MAPK3	S199	R200H	200	Missense	proximal	1	no	8.184	9.929	EPSD	COSMIC	9.358	Gain
CMGC_MAPK_ERK1_MAPK3_ST	Q96Q27	ASB2	P27361	MAPK3	S199	R200P	200	Missense	proximal	1	no	8.184	17.685	EPSD	COSMIC	9.358	Gain
CMGC_MAPK_ERK1_MAPK3_ST	Q96Q27	ASB2	P27361	MAPK3	S323	R316H	316	Missense	distal	-7	no	15.103	15.092	PhosphoSitePlus	COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q96Q27	ASB2	P27361	MAPK3	S323	V322I	322	Missense	proximal	-1	no	15.103	15.056	PhosphoSitePlus	COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q96Q27	ASB2	P27361	MAPK3	S323	P324S	324	Missense	proximal	1	no	15.103	6.050	PhosphoSitePlus	COSMIC	9.358	Loss
CMGC_MAPK_ERK1_MAPK3_ST	P16949	STMN1	P27361	MAPK3	S25	Q18E	18	Missense	distal	-7	no	20.581	20.531	PhosphoSitePlus;EPSD	COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P16949	STMN1	P27361	MAPK3	S38	D44N	44	Missense	distal	6	no	17.700	17.647	EPSD;PhosphoSitePlus	COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P16949	STMN1	P27361	MAPK3	S38	P36L	36	Missense	proximal	-2	no	17.700	16.315	EPSD;PhosphoSitePlus	COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q9UKX7	NUP50	P27361	MAPK3	T184	N178Y	178	Missense	distal	-6	no	13.471	13.341	EPSD	COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q9UKX7	NUP50	P27361	MAPK3	T184	T184A	184	Missense	central	0	yes	13.471	0.000	EPSD	COSMIC	9.358	Loss
CMGC_MAPK_ERK1_MAPK3_ST	Q9UKX7	NUP50	P27361	MAPK3	S221	L224F	224	Missense	distal	3	no	17.386	17.354	EPSD;PhosphoSitePlus	COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q9UKX7	NUP50	P27361	MAPK3	S223	L224F	224	Missense	proximal	1	no	8.218	11.042	EPSD	COSMIC	9.358	Gain
CMGC_MAPK_ERK1_MAPK3_ST	Q9UKX7	NUP50	P27361	MAPK3	T246	M251V	251	Missense	distal	5	no	14.067	14.191	EPSD	COSMIC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q9UKX7	NUP50	P27361	MAPK3	S270	L264I	264	Missense	distal	-6	no	10.911	10.844	EPSD	COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q9UKX7	NUP50	P27361	MAPK3	S270	G274D	274	Missense	distal	4	no	10.911	10.952	EPSD	COSMIC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q9UKX7	NUP50	P27361	MAPK3	S270	G274S	274	Missense	distal	4	no	10.911	11.071	EPSD	COSMIC;CCLE	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q9UKX7	NUP50	P27361	MAPK3	S270	T267A	267	Missense	distal	-3	no	10.911	10.849	EPSD	COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q9UKX7	NUP50	P27361	MAPK3	S315	P316Q	316	Missense	proximal	1	no	15.216	7.272	PhosphoSitePlus;EPSD	COSMIC	9.358	Loss
CMGC_MAPK_ERK1_MAPK3_ST	Q15746	MYLK	P27361	MAPK3	S259	A266V	266	Missense	distal	7	no	9.463	9.435	EPSD	COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q15746	MYLK	P27361	MAPK3	S299	G303C	303	Missense	distal	4	no	13.189	12.846	EPSD	COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q15746	MYLK	P27361	MAPK3	S299	S298Y	298	Missense	proximal	-1	no	13.189	13.112	EPSD	COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q15746	MYLK	P27361	MAPK3	S305	G303C	303	Missense	proximal	-2	no	14.547	13.148	EPSD	COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q15746	MYLK	P27361	MAPK3	S305	S312N	312	Missense	distal	7	no	14.547	14.713	EPSD	COSMIC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q15746	MYLK	P27361	MAPK3	S305	S298Y	298	Missense	distal	-7	no	14.547	14.666	EPSD	COSMIC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q15746	MYLK	P27361	MAPK3	S328	D327N	327	Missense	proximal	-1	no	15.316	15.314	EPSD	COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q15746	MYLK	P27361	MAPK3	S328	E323K	323	Missense	distal	-5	no	15.316	15.304	EPSD	COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q15746	MYLK	P27361	MAPK3	S343	S344F	344	Missense	proximal	1	no	7.254	10.093	EPSD	COSMIC	9.358	Gain
CMGC_MAPK_ERK1_MAPK3_ST	Q15746	MYLK	P27361	MAPK3	S365	P359L	359	Missense	distal	-6	no	17.290	17.043	EPSD	COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q15746	MYLK	P27361	MAPK3	S515	D522Y	522	Missense	distal	7	no	9.561	9.710	EPSD	COSMIC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q15746	MYLK	P27361	MAPK3	S515	S515P	515	Missense	central	0	yes	9.561	0.000	EPSD	COSMIC	9.358	Loss
CMGC_MAPK_ERK1_MAPK3_ST	Q15746	MYLK	P27361	MAPK3	S947	Q949R	949	Missense	proximal	2	no	16.192	16.202	EPSD	COSMIC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q15746	MYLK	P27361	MAPK3	S947	E940K	940	Missense	distal	-7	no	16.192	16.244	EPSD	COSMIC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q15746	MYLK	P27361	MAPK3	S947	P948S	948	Missense	proximal	1	no	16.192	7.139	EPSD	COSMIC;GDSC;CCLE	9.358	Loss
CMGC_MAPK_ERK1_MAPK3_ST	Q15746	MYLK	P27361	MAPK3	S947	S947N	947	Missense	central	0	yes	16.192	0.000	EPSD	COSMIC	9.358	Loss
CMGC_MAPK_ERK1_MAPK3_ST	Q15746	MYLK	P27361	MAPK3	T978	V971G	971	Missense	distal	-7	no	18.294	18.183	EPSD	COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q15746	MYLK	P27361	MAPK3	T978	P976L	976	Missense	proximal	-2	no	18.294	16.910	EPSD	COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q15746	MYLK	P27361	MAPK3	S1208	R1205G	1205	Missense	distal	-3	no	9.454	9.459	EPSD	COSMIC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q15746	MYLK	P27361	MAPK3	T1230	P1232L	1232	Missense	proximal	2	no	16.362	16.341	EPSD	COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q15746	MYLK	P27361	MAPK3	T1337	I1343T	1343	Missense	distal	6	no	13.218	13.633	EPSD	COSMIC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q15746	MYLK	P27361	MAPK3	T1337	P1338S	1338	Missense	proximal	1	no	13.218	4.164	EPSD	COSMIC	9.358	Loss
CMGC_MAPK_ERK1_MAPK3_ST	Q15746	MYLK	P27361	MAPK3	S1659	D1666N	1666	Missense	distal	7	no	14.109	14.168	EPSD	COSMIC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q15746	MYLK	P27361	MAPK3	S1776	P1777S	1777	Missense	proximal	1	no	16.022	6.968	EPSD	COSMIC	9.358	Loss
CMGC_MAPK_ERK1_MAPK3_ST	Q15746	MYLK	P27361	MAPK3	S1776	L1781F	1781	Missense	distal	5	no	16.022	15.868	EPSD	COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q15746	MYLK	P27361	MAPK3	S1779	P1777S	1777	Missense	proximal	-2	no	17.370	16.294	PhosphoSitePlus	COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q15746	MYLK	P27361	MAPK3	S1779	L1781F	1781	Missense	proximal	2	no	17.370	17.343	PhosphoSitePlus	COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q15746	MYLK	P27361	MAPK3	S1788	L1781F	1781	Missense	distal	-7	no	9.286	9.361	EPSD	COSMIC	9.358	Gain
CMGC_MAPK_ERK1_MAPK3_ST	O75581	LRP6	P27361	MAPK3	S1471	H1464Y	1464	Missense	distal	-7	no	9.564	9.611	EPSD	COSMIC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	O75581	LRP6	P27361	MAPK3	S1471	S1469A	1469	Missense	proximal	-2	no	9.564	8.289	EPSD	COSMIC	9.358	Loss
CMGC_MAPK_ERK1_MAPK3_ST	O75581	LRP6	P27361	MAPK3	S1490	S1490F	1490	Missense	central	0	yes	18.153	0.000	PhosphoSitePlus;EPSD	COSMIC	9.358	Loss
CMGC_MAPK_ERK1_MAPK3_ST	O75581	LRP6	P27361	MAPK3	S1490	S1496L	1496	Missense	distal	6	no	18.153	17.796	PhosphoSitePlus;EPSD	COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	O75581	LRP6	P27361	MAPK3	S1508	S1508R	1508	Missense	central	0	yes	16.432	0.000	EPSD	COSMIC	9.358	Loss
CMGC_MAPK_ERK1_MAPK3_ST	O75581	LRP6	P27361	MAPK3	S1508	S1514A	1514	Missense	distal	6	no	16.432	15.907	EPSD	COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	O75581	LRP6	P27361	MAPK3	S1508	F1502C	1502	Missense	distal	-6	no	16.432	16.340	EPSD	COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	O75581	LRP6	P27361	MAPK3	S1508	N1507K	1507	Missense	proximal	-1	no	16.432	16.426	EPSD	COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	O75581	LRP6	P27361	MAPK3	T1511	S1508R	1508	Missense	distal	-3	no	9.366	9.328	EPSD	COSMIC	9.358	Loss
CMGC_MAPK_ERK1_MAPK3_ST	O75581	LRP6	P27361	MAPK3	T1511	S1514A	1514	Missense	distal	3	no	9.366	9.322	EPSD	COSMIC	9.358	Loss
CMGC_MAPK_ERK1_MAPK3_ST	O75581	LRP6	P27361	MAPK3	T1511	N1507K	1507	Missense	distal	-4	no	9.366	9.343	EPSD	COSMIC	9.358	Loss
CMGC_MAPK_ERK1_MAPK3_ST	O75581	LRP6	P27361	MAPK3	S1521	P1528H	1528	Missense	distal	7	no	11.130	11.189	EPSD	COSMIC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	O75581	LRP6	P27361	MAPK3	S1521	Y1520C	1520	Missense	proximal	-1	no	11.130	10.979	EPSD	COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	O75581	LRP6	P27361	MAPK3	S1521	S1514A	1514	Missense	distal	-7	no	11.130	11.279	EPSD	COSMIC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	O75581	LRP6	P27361	MAPK3	S1521	R1523Q	1523	Missense	proximal	2	no	11.130	11.120	EPSD	COSMIC;GDSC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	O75581	LRP6	P27361	MAPK3	T1530	P1528H	1528	Missense	proximal	-2	no	17.151	15.924	EPSD	COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	O75581	LRP6	P27361	MAPK3	T1530	R1523Q	1523	Missense	distal	-7	no	17.151	17.150	EPSD	COSMIC;GDSC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	O75581	LRP6	P27361	MAPK3	T1572	P1571S	1571	Missense	proximal	-1	no	17.564	17.558	EPSD;PhosphoSitePlus	COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	O75581	LRP6	P27361	MAPK3	S1575	E1581Q	1581	Missense	distal	6	no	10.244	10.065	EPSD	COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	O75581	LRP6	P27361	MAPK3	S1575	P1571S	1571	Missense	distal	-4	no	10.244	10.271	EPSD	COSMIC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	O75581	LRP6	P27361	MAPK3	S1590	P1589R	1589	Missense	proximal	-1	no	19.917	19.869	EPSD	COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	O75581	LRP6	P27361	MAPK3	S1607	H1600Q	1600	Missense	distal	-7	no	21.647	21.658	EPSD	COSMIC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	O75581	LRP6	P27361	MAPK3	S1607	P1604L	1604	Missense	distal	-3	no	21.647	21.563	EPSD	COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q02447	SP3	P27361	MAPK3	S73	D77H	77	Missense	distal	4	no	18.394	18.373	PhosphoSitePlus	COSMIC;CCLE	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q02447	SP3	P27361	MAPK3	S73	D77E	77	Missense	distal	4	no	18.394	18.414	PhosphoSitePlus	COSMIC;CCLE	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q02447	SP3	P27361	MAPK3	T115	S113T	113	Missense	proximal	-2	no	14.514	14.604	EPSD	COSMIC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q02447	SP3	P27361	MAPK3	S317	I320V	320	Missense	distal	3	no	16.716	16.730	EPSD	COSMIC;GDSC;CCLE	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q02447	SP3	P27361	MAPK3	S317	R315Q	315	Missense	proximal	-2	no	16.716	16.352	EPSD	COSMIC;GDSC;CCLE	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q02447	SP3	P27361	MAPK3	S317	R315L	315	Missense	proximal	-2	no	16.716	16.732	EPSD	COSMIC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q02447	SP3	P27361	MAPK3	S317	T323S	323	Missense	distal	6	no	16.716	16.871	EPSD	COSMIC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q02447	SP3	P27361	MAPK3	S317	R311K	311	Missense	distal	-6	no	16.716	16.718	EPSD	COSMIC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q02447	SP3	P27361	MAPK3	S317	R315P	315	Missense	proximal	-2	no	16.716	18.116	EPSD	COSMIC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q8IX03	WWC1	P27361	MAPK3	S270	Q276R	276	Missense	distal	6	no	11.158	11.228	EPSD	COSMIC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q8IX03	WWC1	P27361	MAPK3	S270	P272R	272	Missense	proximal	2	no	11.158	11.148	EPSD	COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q8IX03	WWC1	P27361	MAPK3	S358	G365W	365	Missense	distal	7	no	15.901	16.507	EPSD	COSMIC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q8IX03	WWC1	P27361	MAPK3	S358	R360H	360	Missense	proximal	2	no	15.901	15.898	EPSD	COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q8IX03	WWC1	P27361	MAPK3	S438	S434F	434	Missense	distal	-4	no	16.373	16.184	EPSD	COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q8IX03	WWC1	P27361	MAPK3	S441	S434F	434	Missense	distal	-7	no	11.099	11.318	EPSD	COSMIC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q8IX03	WWC1	P27361	MAPK3	S441	S448Y	448	Missense	distal	7	no	11.099	11.354	EPSD	COSMIC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q8IX03	WWC1	P27361	MAPK3	T527	L521V	521	Missense	distal	-6	no	16.615	16.617	EPSD	COSMIC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q8IX03	WWC1	P27361	MAPK3	S876	E873K	873	Missense	distal	-3	no	14.104	14.073	EPSD	COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q8IX03	WWC1	P27361	MAPK3	S876	D869H	869	Missense	distal	-7	no	14.104	14.134	EPSD	COSMIC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q8IX03	WWC1	P27361	MAPK3	S876	G881E	881	Missense	distal	5	no	14.104	14.145	EPSD	COSMIC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q8IX03	WWC1	P27361	MAPK3	S876	G881V	881	Missense	distal	5	no	14.104	13.902	EPSD	COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q8IX03	WWC1	P27361	MAPK3	T895	P900T	900	Missense	distal	5	no	16.724	16.631	EPSD	COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q8IX03	WWC1	P27361	MAPK3	T895	P898L	898	Missense	distal	3	no	16.724	16.687	EPSD	COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q8IX03	WWC1	P27361	MAPK3	T895	P900S	900	Missense	distal	5	no	16.724	16.767	EPSD	COSMIC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q8IX03	WWC1	P27361	MAPK3	T895	P896L	896	Missense	proximal	1	no	16.724	7.686	EPSD	COSMIC	9.358	Loss
CMGC_MAPK_ERK1_MAPK3_ST	Q8IX03	WWC1	P27361	MAPK3	S899	P900T	900	Missense	proximal	1	no	16.387	7.510	EPSD	COSMIC	9.358	Loss
CMGC_MAPK_ERK1_MAPK3_ST	Q8IX03	WWC1	P27361	MAPK3	S899	P898L	898	Missense	proximal	-1	no	16.387	16.292	EPSD	COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q8IX03	WWC1	P27361	MAPK3	S899	P900S	900	Missense	proximal	1	no	16.387	7.333	EPSD	COSMIC	9.358	Loss
CMGC_MAPK_ERK1_MAPK3_ST	Q8IX03	WWC1	P27361	MAPK3	S899	P896L	896	Missense	distal	-3	no	16.387	16.303	EPSD	COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q8IX03	WWC1	P27361	MAPK3	T912	P913S	913	Missense	proximal	1	no	14.243	5.189	EPSD	COSMIC	9.358	Loss
CMGC_MAPK_ERK1_MAPK3_ST	Q8IX03	WWC1	P27361	MAPK3	S914	P913S	913	Missense	proximal	-1	no	9.490	9.484	EPSD	COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q8IX03	WWC1	P27361	MAPK3	T929	K928Q	928	Missense	proximal	-1	no	10.266	10.240	EPSD	COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q8IX03	WWC1	P27361	MAPK3	S931	K928Q	928	Missense	distal	-3	no	16.230	16.236	EPSD	COSMIC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P11362	FGFR1	P27361	MAPK3	S450	S451F	451	Missense	proximal	1	no	7.350	10.190	EPSD	COSMIC	9.358	Gain
CMGC_MAPK_ERK1_MAPK3_ST	P11362	FGFR1	P27361	MAPK3	T454	S451F	451	Missense	distal	-3	no	14.335	14.194	EPSD	COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P11362	FGFR1	P27361	MAPK3	T454	R448Q	448	Missense	distal	-6	no	14.335	14.345	EPSD	COSMIC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P11362	FGFR1	P27361	MAPK3	T454	S451C	451	Missense	distal	-3	no	14.335	14.158	EPSD	COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P11362	FGFR1	P27361	MAPK3	T454	G459R	459	Missense	distal	5	no	14.335	14.256	EPSD	COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P11362	FGFR1	P27361	MAPK3	T454	T454N	454	Missense	central	0	yes	14.335	0.000	EPSD	COSMIC	9.358	Loss
CMGC_MAPK_ERK1_MAPK3_ST	P11362	FGFR1	P27361	MAPK3	T454	S447P	447	Missense	distal	-7	no	14.335	14.373	EPSD	COSMIC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P11362	FGFR1	P27361	MAPK3	T454	M456I	456	Missense	proximal	2	no	14.335	14.344	EPSD	COSMIC;GDSC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P11362	FGFR1	P27361	MAPK3	T454	M456V	456	Missense	proximal	2	no	14.335	14.354	EPSD	COSMIC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P11362	FGFR1	P27361	MAPK3	T454	S447L	447	Missense	distal	-7	no	14.335	14.480	EPSD	COSMIC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P11362	FGFR1	P27361	MAPK3	T454	R448L	448	Missense	distal	-6	no	14.335	14.164	EPSD	COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P11362	FGFR1	P27361	MAPK3	T454	L457R	457	Missense	distal	3	no	14.335	14.345	EPSD	COSMIC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P11362	FGFR1	P27361	MAPK3	S588	E582G	582	Missense	distal	-6	no	9.602	9.556	EPSD	COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P11362	FGFR1	P27361	MAPK3	S588	E582K	582	Missense	distal	-6	no	9.602	9.460	EPSD	COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P11362	FGFR1	P27361	MAPK3	S588	E592G	592	Missense	distal	4	no	9.602	9.541	EPSD	COSMIC;GDSC;CCLE	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P11362	FGFR1	P27361	MAPK3	S588	P591Q	591	Missense	distal	3	no	9.602	9.576	EPSD	COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P11362	FGFR1	P27361	MAPK3	S588	E592K	592	Missense	distal	4	no	9.602	9.564	EPSD	COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P11362	FGFR1	P27361	MAPK3	S588	P587H	587	Missense	proximal	-1	no	9.602	9.557	EPSD	COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P11362	FGFR1	P27361	MAPK3	S777	S779C	779	Missense	proximal	2	no	17.575	17.514	PhosphoSitePlus	COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P11362	FGFR1	P27361	MAPK3	S777	R784Q	784	Missense	distal	7	no	17.575	17.605	PhosphoSitePlus	COSMIC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P11362	FGFR1	P27361	MAPK3	S777	R784W	784	Missense	distal	7	no	17.575	18.152	PhosphoSitePlus	COSMIC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P11362	FGFR1	P27361	MAPK3	S777	P772S	772	Missense	distal	-5	no	17.575	17.580	PhosphoSitePlus	COSMIC;GDSC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P11362	FGFR1	P27361	MAPK3	S777	D782N	782	Missense	distal	5	no	17.575	17.495	PhosphoSitePlus	COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P11362	FGFR1	P27361	MAPK3	S777	P772H	772	Missense	distal	-5	no	17.575	17.544	PhosphoSitePlus	COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P11362	FGFR1	P27361	MAPK3	S779	S779C	779	Missense	central	0	yes	10.185	0.000	EPSD	COSMIC	9.358	Loss
CMGC_MAPK_ERK1_MAPK3_ST	P11362	FGFR1	P27361	MAPK3	S779	R784Q	784	Missense	distal	5	no	10.185	10.184	EPSD	COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P11362	FGFR1	P27361	MAPK3	S779	R784W	784	Missense	distal	5	no	10.185	9.717	EPSD	COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P11362	FGFR1	P27361	MAPK3	S779	P772S	772	Missense	distal	-7	no	10.185	10.148	EPSD	COSMIC;GDSC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P11362	FGFR1	P27361	MAPK3	S779	D782N	782	Missense	distal	3	no	10.185	10.175	EPSD	COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P11362	FGFR1	P27361	MAPK3	S779	P772H	772	Missense	distal	-7	no	10.185	10.219	EPSD	COSMIC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P11362	FGFR1	P27361	MAPK3	S785	G791E	791	Missense	distal	6	no	9.263	9.364	EPSD	COSMIC	9.358	Gain
CMGC_MAPK_ERK1_MAPK3_ST	P11362	FGFR1	P27361	MAPK3	S789	S790P	790	Missense	proximal	1	no	6.486	15.540	EPSD	COSMIC	9.358	Gain
CMGC_MAPK_ERK1_MAPK3_ST	P11362	FGFR1	P27361	MAPK3	S797	H798Y	798	Missense	proximal	1	no	8.661	9.369	EPSD	COSMIC	9.358	Gain
CMGC_MAPK_ERK1_MAPK3_ST	O15525	MAFG	P27361	MAPK3	S124	A118T	118	Missense	distal	-6	no	15.420	15.568	PhosphoSitePlus	COSMIC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	O15525	MAFG	P27361	MAPK3	S124	R130Q	130	Missense	distal	6	no	15.420	15.351	PhosphoSitePlus	COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P14784	IL2RB	P27361	MAPK3	S431	G436V	436	Missense	distal	5	no	14.421	14.220	EPSD	COSMIC;CCLE	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P14784	IL2RB	P27361	MAPK3	S458	R465K	465	Missense	distal	7	no	9.727	9.733	EPSD	COSMIC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P14784	IL2RB	P27361	MAPK3	S458	G451D	451	Missense	distal	-7	no	9.727	9.732	EPSD	COSMIC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P14784	IL2RB	P27361	MAPK3	T476	P474H	474	Missense	proximal	-2	no	15.038	13.810	PhosphoSitePlus	COSMIC;GDSC;CCLE	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P14784	IL2RB	P27361	MAPK3	T533	S538F	538	Missense	distal	5	no	9.774	9.349	EPSD	COSMIC	9.358	Loss
CMGC_MAPK_ERK1_MAPK3_ST	P14784	IL2RB	P27361	MAPK3	T533	R528H	528	Missense	distal	-5	no	9.774	9.783	EPSD	COSMIC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P14784	IL2RB	P27361	MAPK3	T533	A527S	527	Missense	distal	-6	no	9.774	10.090	EPSD	COSMIC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P14784	IL2RB	P27361	MAPK3	S538	Q543H	543	Missense	distal	5	no	10.159	10.197	EPSD	COSMIC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P14784	IL2RB	P27361	MAPK3	S538	S538F	538	Missense	central	0	yes	10.159	0.000	EPSD	COSMIC	9.358	Loss
CMGC_MAPK_ERK1_MAPK3_ST	P06239	LCK	P27361	MAPK3	S59	P57L	57	Missense	proximal	-2	no	17.222	15.837	PhosphoSitePlus	COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P06239	LCK	P27361	MAPK3	S75	D77N	77	Missense	proximal	2	no	9.553	9.547	EPSD	COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P06239	LCK	P27361	MAPK3	S75	G78R	78	Missense	distal	3	no	9.553	9.546	EPSD	COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P06239	LCK	P27361	MAPK3	S156	F151S	151	Missense	distal	-5	no	10.064	10.198	EPSD	COSMIC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P06239	LCK	P27361	MAPK3	S156	G161R	161	Missense	distal	5	no	10.064	9.985	EPSD	COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P06239	LCK	P27361	MAPK3	S156	A160V	160	Missense	distal	4	no	10.064	10.172	EPSD	COSMIC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P06239	LCK	P27361	MAPK3	S162	G161R	161	Missense	proximal	-1	no	9.683	9.707	EPSD	COSMIC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P06239	LCK	P27361	MAPK3	S162	A160V	160	Missense	proximal	-2	no	9.683	10.380	EPSD	COSMIC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P06239	LCK	P27361	MAPK3	S194	P200L	200	Missense	distal	6	no	16.825	16.598	EPSD	COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P06239	LCK	P27361	MAPK3	S194	D187N	187	Missense	distal	-7	no	16.825	16.850	EPSD	COSMIC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P06239	LCK	P27361	MAPK3	S194	I197F	197	Missense	distal	3	no	16.825	16.812	EPSD	COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P06239	LCK	P27361	MAPK3	S281	P282L	282	Missense	proximal	1	no	15.533	6.495	EPSD	COSMIC	9.358	Loss
CMGC_MAPK_ERK1_MAPK3_ST	P06239	LCK	P27361	MAPK3	S281	A287V	287	Missense	distal	6	no	15.533	15.621	EPSD	COSMIC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P06239	LCK	P27361	MAPK3	S281	K276E	276	Missense	distal	-5	no	15.533	15.545	EPSD	COSMIC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P06239	LCK	P27361	MAPK3	T330	P331S	331	Missense	proximal	1	no	15.376	6.323	EPSD	COSMIC	9.358	Loss
CMGC_MAPK_ERK1_MAPK3_ST	P06239	LCK	P27361	MAPK3	S373	S377G	377	Missense	distal	4	no	9.982	9.821	EPSD	COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P06239	LCK	P27361	MAPK3	S373	K379E	379	Missense	distal	6	no	9.982	10.058	EPSD	COSMIC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P06239	LCK	P27361	MAPK3	S373	R366W	366	Missense	distal	-7	no	9.982	10.227	EPSD	COSMIC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P06239	LCK	P27361	MAPK3	S373	N369S	369	Missense	distal	-4	no	9.982	10.043	EPSD	COSMIC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P06239	LCK	P27361	MAPK3	T501	G503D	503	Missense	proximal	2	no	11.178	11.183	EPSD	COSMIC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P06239	LCK	P27361	MAPK3	T501	A500T	500	Missense	proximal	-1	no	11.178	11.281	EPSD	COSMIC;GDSC;CCLE	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P06239	LCK	P27361	MAPK3	T501	Q508H	508	Missense	distal	7	no	11.178	11.116	EPSD	COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P42702	LIFR	P27361	MAPK3	S368	S374G	374	Missense	distal	6	no	10.615	10.383	EPSD	COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P42702	LIFR	P27361	MAPK3	S368	S374I	374	Missense	distal	6	no	10.615	10.045	EPSD	COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P42702	LIFR	P27361	MAPK3	S368	P364T	364	Missense	distal	-4	no	10.615	10.584	EPSD	COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P42702	LIFR	P27361	MAPK3	S368	F375V	375	Missense	distal	7	no	10.615	10.442	EPSD	COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P42702	LIFR	P27361	MAPK3	S534	H528Y	528	Missense	distal	-6	no	17.155	17.067	EPSD	COSMIC;GDSC;CCLE	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P42702	LIFR	P27361	MAPK3	S534	K537N	537	Missense	distal	3	no	17.155	17.158	EPSD	COSMIC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P42702	LIFR	P27361	MAPK3	T541	K537N	537	Missense	distal	-4	no	10.356	10.379	EPSD	COSMIC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P42702	LIFR	P27361	MAPK3	T541	S546N	546	Missense	distal	5	no	10.356	10.234	EPSD	COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P42702	LIFR	P27361	MAPK3	S887	V888F	888	Missense	proximal	1	no	8.215	11.424	EPSD	COSMIC	9.358	Gain
CMGC_MAPK_ERK1_MAPK3_ST	P42702	LIFR	P27361	MAPK3	T904	P902L	902	Missense	proximal	-2	no	15.727	14.342	EPSD	COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P42702	LIFR	P27361	MAPK3	T904	T904A	904	Missense	central	0	yes	15.727	0.000	EPSD	COSMIC	9.358	Loss
CMGC_MAPK_ERK1_MAPK3_ST	P42702	LIFR	P27361	MAPK3	S927	E934K	934	Missense	distal	7	no	16.348	16.419	EPSD	COSMIC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P42702	LIFR	P27361	MAPK3	S1041	P1042S	1042	Missense	proximal	1	no	17.599	8.546	EPSD	COSMIC	9.358	Loss
CMGC_MAPK_ERK1_MAPK3_ST	P42702	LIFR	P27361	MAPK3	S1041	R1046I	1046	Missense	distal	5	no	17.599	17.350	EPSD	COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P42702	LIFR	P27361	MAPK3	S1041	P1042L	1042	Missense	proximal	1	no	17.599	8.561	EPSD	COSMIC	9.358	Loss
CMGC_MAPK_ERK1_MAPK3_ST	P42702	LIFR	P27361	MAPK3	S1041	V1040E	1040	Missense	proximal	-1	no	17.599	17.659	EPSD	COSMIC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P42702	LIFR	P27361	MAPK3	S1044	P1042S	1042	Missense	proximal	-2	no	17.176	16.100	PhosphoSitePlus	COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P42702	LIFR	P27361	MAPK3	S1044	R1046I	1046	Missense	proximal	2	no	17.176	17.153	PhosphoSitePlus	COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P42702	LIFR	P27361	MAPK3	S1044	P1042L	1042	Missense	proximal	-2	no	17.176	15.792	PhosphoSitePlus	COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P42702	LIFR	P27361	MAPK3	S1044	V1040E	1040	Missense	distal	-4	no	17.176	17.304	PhosphoSitePlus	COSMIC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P42702	LIFR	P27361	MAPK3	S1044	D1049Y	1049	Missense	distal	5	no	17.176	17.002	PhosphoSitePlus	COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P42702	LIFR	P27361	MAPK3	S1056	P1060A	1060	Missense	distal	4	no	11.583	11.301	EPSD	COSMIC;GDSC;CCLE	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P42702	LIFR	P27361	MAPK3	S1056	D1049Y	1049	Missense	distal	-7	no	11.583	11.659	EPSD	COSMIC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P42702	LIFR	P27361	MAPK3	S1059	P1060A	1060	Missense	proximal	1	no	16.075	6.835	EPSD	COSMIC;GDSC;CCLE	9.358	Loss
CMGC_MAPK_ERK1_MAPK3_ST	P42702	LIFR	P27361	MAPK3	S1062	P1060A	1060	Missense	proximal	-2	no	11.245	8.894	EPSD	COSMIC;GDSC;CCLE	9.358	Loss
CMGC_MAPK_ERK1_MAPK3_ST	P42702	LIFR	P27361	MAPK3	S1062	F1068L	1068	Missense	distal	6	no	11.245	11.602	EPSD	COSMIC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P42702	LIFR	P27361	MAPK3	S1077	G1084E	1084	Missense	distal	7	no	17.669	17.634	EPSD	COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P42702	LIFR	P27361	MAPK3	S1077	P1072H	1072	Missense	distal	-5	no	17.669	17.638	EPSD	COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P42702	LIFR	P27361	MAPK3	S1086	G1084E	1084	Missense	proximal	-2	no	12.169	12.640	EPSD	COSMIC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P42702	LIFR	P27361	MAPK3	S1086	N1089H	1089	Missense	distal	3	no	12.169	12.176	EPSD	COSMIC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P42702	LIFR	P27361	MAPK3	T1088	N1089H	1089	Missense	proximal	1	no	5.388	11.721	EPSD	COSMIC	9.358	Gain
CMGC_MAPK_ERK1_MAPK3_ST	Q14247	CTTN	P27361	MAPK3	S150	G143W	143	Missense	distal	-7	no	9.177	9.468	EPSD	COSMIC	9.358	Gain
CMGC_MAPK_ERK1_MAPK3_ST	Q14247	CTTN	P27361	MAPK3	T401	Q394K	394	Missense	distal	-7	no	14.928	14.930	EPSD	COSMIC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q14247	CTTN	P27361	MAPK3	T401	R396T	396	Missense	distal	-5	no	14.928	14.958	EPSD	COSMIC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q14247	CTTN	P27361	MAPK3	S405	T411I	411	Missense	distal	6	no	18.528	18.113	PhosphoSitePlus;EPSD	COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q14247	CTTN	P27361	MAPK3	S418	T411I	411	Missense	distal	-7	no	18.198	18.313	EPSD;PhosphoSitePlus	COSMIC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q14247	CTTN	P27361	MAPK3	S418	V420I	420	Missense	proximal	2	no	18.198	18.188	EPSD;PhosphoSitePlus	COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q14247	CTTN	P27361	MAPK3	S426	V420I	420	Missense	distal	-6	no	11.240	11.171	EPSD	COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q14247	CTTN	P27361	MAPK3	S426	S426F	426	Missense	central	0	yes	11.240	0.000	EPSD	COSMIC	9.358	Loss
CMGC_MAPK_ERK1_MAPK3_ST	Q14247	CTTN	P27361	MAPK3	S432	S438N	438	Missense	distal	6	no	9.815	9.586	EPSD	COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q14247	CTTN	P27361	MAPK3	S432	V437L	437	Missense	distal	5	no	9.815	9.811	EPSD	COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q14247	CTTN	P27361	MAPK3	S432	S426F	426	Missense	distal	-6	no	9.815	9.348	EPSD	COSMIC	9.358	Loss
CMGC_MAPK_ERK1_MAPK3_ST	P62070	RRAS2	P27361	MAPK3	S186	Q179R	179	Missense	distal	-7	no	20.949	20.950	PhosphoSitePlus	COSMIC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q08499	PDE4D	P27361	MAPK3	S18	G13S	13	Missense	distal	-5	no	10.692	10.736	EPSD	COSMIC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q08499	PDE4D	P27361	MAPK3	S18	G22S	22	Missense	distal	4	no	10.692	10.853	EPSD	COSMIC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q08499	PDE4D	P27361	MAPK3	S18	R11Q	11	Missense	distal	-7	no	10.692	10.691	EPSD	COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q08499	PDE4D	P27361	MAPK3	S164	D167N	167	Missense	distal	3	no	13.348	13.337	EPSD	COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q08499	PDE4D	P27361	MAPK3	S164	S171N	171	Missense	distal	7	no	13.348	13.513	EPSD	COSMIC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q08499	PDE4D	P27361	MAPK3	S171	D167N	167	Missense	distal	-4	no	15.078	15.052	EPSD	COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q08499	PDE4D	P27361	MAPK3	S171	S171N	171	Missense	central	0	yes	15.078	0.000	EPSD	COSMIC	9.358	Loss
CMGC_MAPK_ERK1_MAPK3_ST	Q08499	PDE4D	P27361	MAPK3	S171	L176P	176	Missense	distal	5	no	15.078	15.306	EPSD	COSMIC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q08499	PDE4D	P27361	MAPK3	S202	R208Q	208	Missense	distal	6	no	16.308	16.239	EPSD	COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q08499	PDE4D	P27361	MAPK3	S202	S207F	207	Missense	distal	5	no	16.308	15.884	EPSD	COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q08499	PDE4D	P27361	MAPK3	S207	R208Q	208	Missense	proximal	1	no	8.019	9.576	EPSD	COSMIC	9.358	Gain
CMGC_MAPK_ERK1_MAPK3_ST	Q08499	PDE4D	P27361	MAPK3	S348	P349S	349	Missense	proximal	1	no	16.099	7.046	EPSD	COSMIC	9.358	Loss
CMGC_MAPK_ERK1_MAPK3_ST	Q08499	PDE4D	P27361	MAPK3	S348	S348F	348	Missense	central	0	yes	16.099	0.000	EPSD	COSMIC	9.358	Loss
CMGC_MAPK_ERK1_MAPK3_ST	Q08499	PDE4D	P27361	MAPK3	S362	Q363P	363	Missense	proximal	1	no	11.284	19.228	EPSD	COSMIC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q08499	PDE4D	P27361	MAPK3	S374	H372N	372	Missense	proximal	-2	no	9.804	9.012	EPSD	COSMIC	9.358	Loss
CMGC_MAPK_ERK1_MAPK3_ST	Q08499	PDE4D	P27361	MAPK3	S374	S375F	375	Missense	proximal	1	no	9.804	12.644	EPSD	COSMIC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q08499	PDE4D	P27361	MAPK3	S657	E655G	655	Missense	proximal	-2	no	15.411	14.941	EPSD	COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q08499	PDE4D	P27361	MAPK3	S715	P716S	716	Missense	proximal	1	no	20.327	11.274	EPSD	COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q08499	PDE4D	P27361	MAPK3	S715	P718S	718	Missense	distal	3	no	20.327	20.323	EPSD	COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q08499	PDE4D	P27361	MAPK3	S717	P716S	716	Missense	proximal	-1	no	14.599	14.593	EPSD	COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q08499	PDE4D	P27361	MAPK3	S717	P718S	718	Missense	proximal	1	no	14.599	5.546	EPSD	COSMIC	9.358	Loss
CMGC_MAPK_ERK1_MAPK3_ST	Q08499	PDE4D	P27361	MAPK3	S806	R805L	805	Missense	proximal	-1	no	18.466	18.419	EPSD	COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q08499	PDE4D	P27361	MAPK3	S806	S806A	806	Missense	central	0	yes	18.466	0.000	EPSD	COSMIC	9.358	Loss
CMGC_MAPK_ERK1_MAPK3_ST	O95644	NFATC1	P27361	MAPK3	S117	P113S	113	Missense	distal	-4	no	16.395	16.422	EPSD	COSMIC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	O95644	NFATC1	P27361	MAPK3	S117	A112T	112	Missense	distal	-5	no	16.395	16.478	EPSD	COSMIC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	O95644	NFATC1	P27361	MAPK3	S117	P118L	118	Missense	proximal	1	no	16.395	7.357	EPSD	COSMIC	9.358	Loss
CMGC_MAPK_ERK1_MAPK3_ST	O95644	NFATC1	P27361	MAPK3	S151	K149R	149	Missense	proximal	-2	no	13.591	14.532	EPSD	COSMIC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	O95644	NFATC1	P27361	MAPK3	S151	S153F	153	Missense	proximal	2	no	13.591	13.541	EPSD	COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	O95644	NFATC1	P27361	MAPK3	S172	D167H	167	Missense	distal	-5	no	13.563	13.562	PhosphoSitePlus	COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	O95644	NFATC1	P27361	MAPK3	S175	R180Q	180	Missense	distal	5	no	9.388	9.386	EPSD	COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	O95644	NFATC1	P27361	MAPK3	S211	Q206H	206	Missense	distal	-5	no	13.644	13.661	EPSD	COSMIC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	O95644	NFATC1	P27361	MAPK3	S211	T214I	214	Missense	distal	3	no	13.644	13.606	EPSD	COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	O95644	NFATC1	P27361	MAPK3	S233	S237P	237	Missense	distal	4	no	16.952	16.904	EPSD	COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	O95644	NFATC1	P27361	MAPK3	S233	C228Y	228	Missense	distal	-5	no	16.952	17.051	EPSD	COSMIC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	O95644	NFATC1	P27361	MAPK3	S233	S233F	233	Missense	central	0	yes	16.952	0.000	EPSD	COSMIC	9.358	Loss
CMGC_MAPK_ERK1_MAPK3_ST	O95644	NFATC1	P27361	MAPK3	S233	R235W	235	Missense	proximal	2	no	16.952	16.892	EPSD	COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	O95644	NFATC1	P27361	MAPK3	S237	S237P	237	Missense	central	0	yes	13.662	0.000	EPSD	COSMIC	9.358	Loss
CMGC_MAPK_ERK1_MAPK3_ST	O95644	NFATC1	P27361	MAPK3	S237	S233F	233	Missense	distal	-4	no	13.662	13.473	EPSD	COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	O95644	NFATC1	P27361	MAPK3	S237	R235W	235	Missense	proximal	-2	no	13.662	11.765	EPSD	COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	O95644	NFATC1	P27361	MAPK3	S239	S237P	237	Missense	proximal	-2	no	9.105	10.181	EPSD	COSMIC	9.358	Gain
CMGC_MAPK_ERK1_MAPK3_ST	O95644	NFATC1	P27361	MAPK3	S241	S237P	237	Missense	distal	-4	no	16.639	16.612	EPSD	COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	O95644	NFATC1	P27361	MAPK3	S241	R235W	235	Missense	distal	-6	no	16.639	16.117	EPSD	COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	O95644	NFATC1	P27361	MAPK3	S256	S257F	257	Missense	proximal	1	no	6.800	9.640	EPSD	COSMIC	9.358	Gain
CMGC_MAPK_ERK1_MAPK3_ST	O95644	NFATC1	P27361	MAPK3	S261	S257F	257	Missense	distal	-4	no	16.253	16.064	EPSD	COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	O95644	NFATC1	P27361	MAPK3	S261	A260T	260	Missense	proximal	-1	no	16.253	16.356	EPSD	COSMIC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	O95644	NFATC1	P27361	MAPK3	S261	R258I	258	Missense	distal	-3	no	16.253	16.179	EPSD	COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	O95644	NFATC1	P27361	MAPK3	S261	R255K	255	Missense	distal	-6	no	16.253	16.255	EPSD	COSMIC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	O95644	NFATC1	P27361	MAPK3	S278	T284M	284	Missense	distal	6	no	18.844	18.350	EPSD	COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	O95644	NFATC1	P27361	MAPK3	S282	S286L	286	Missense	distal	4	no	17.928	17.725	EPSD	COSMIC;GDSC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	O95644	NFATC1	P27361	MAPK3	S282	P287L	287	Missense	distal	5	no	17.928	17.700	EPSD	COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	O95644	NFATC1	P27361	MAPK3	S282	T284M	284	Missense	proximal	2	no	17.928	17.896	EPSD	COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	O95644	NFATC1	P27361	MAPK3	T284	S286L	286	Missense	proximal	2	no	16.135	16.112	EPSD	COSMIC;GDSC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	O95644	NFATC1	P27361	MAPK3	T284	P287L	287	Missense	distal	3	no	16.135	16.098	EPSD	COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	O95644	NFATC1	P27361	MAPK3	T284	T284M	284	Missense	central	0	yes	16.135	0.000	EPSD	COSMIC	9.358	Loss
CMGC_MAPK_ERK1_MAPK3_ST	O95644	NFATC1	P27361	MAPK3	S286	S286L	286	Missense	central	0	yes	14.954	0.000	EPSD	COSMIC;GDSC	9.358	Loss
CMGC_MAPK_ERK1_MAPK3_ST	O95644	NFATC1	P27361	MAPK3	S286	R292W	292	Missense	distal	6	no	14.954	14.131	EPSD	COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	O95644	NFATC1	P27361	MAPK3	S286	P287L	287	Missense	proximal	1	no	14.954	5.916	EPSD	COSMIC	9.358	Loss
CMGC_MAPK_ERK1_MAPK3_ST	O95644	NFATC1	P27361	MAPK3	S286	R292Q	292	Missense	distal	6	no	14.954	14.885	EPSD	COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	O95644	NFATC1	P27361	MAPK3	S286	T284M	284	Missense	proximal	-2	no	14.954	13.186	EPSD	COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	O95644	NFATC1	P27361	MAPK3	S290	S286L	286	Missense	distal	-4	no	17.580	17.440	EPSD	COSMIC;GDSC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	O95644	NFATC1	P27361	MAPK3	S290	R292W	292	Missense	proximal	2	no	17.580	17.519	EPSD	COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	O95644	NFATC1	P27361	MAPK3	S290	P287L	287	Missense	distal	-3	no	17.580	17.496	EPSD	COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	O95644	NFATC1	P27361	MAPK3	S290	R292Q	292	Missense	proximal	2	no	17.580	17.571	EPSD	COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	O95644	NFATC1	P27361	MAPK3	S290	T284M	284	Missense	distal	-6	no	17.580	17.327	EPSD	COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	O95644	NFATC1	P27361	MAPK3	S359	D365N	365	Missense	distal	6	no	16.717	16.664	EPSD	COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	O95644	NFATC1	P27361	MAPK3	S359	P363H	363	Missense	distal	4	no	16.717	16.625	EPSD	COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	O95644	NFATC1	P27361	MAPK3	S373	R378W	378	Missense	distal	5	no	9.537	9.069	EPSD	COSMIC	9.358	Loss
CMGC_MAPK_ERK1_MAPK3_ST	O95644	NFATC1	P27361	MAPK3	S373	A367G	367	Missense	distal	-6	no	9.537	9.791	EPSD	COSMIC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	O95644	NFATC1	P27361	MAPK3	S373	E369K	369	Missense	distal	-4	no	9.537	9.477	EPSD	COSMIC;CCLE	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	O95644	NFATC1	P27361	MAPK3	S373	S373C	373	Missense	central	0	yes	9.537	0.000	EPSD	COSMIC	9.358	Loss
CMGC_MAPK_ERK1_MAPK3_ST	O95644	NFATC1	P27361	MAPK3	S403	W396G	396	Missense	distal	-7	no	17.502	17.211	EPSD	COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	O95644	NFATC1	P27361	MAPK3	S403	P410L	410	Missense	distal	7	no	17.502	17.694	EPSD	COSMIC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	O95644	NFATC1	P27361	MAPK3	S403	S406F	406	Missense	distal	3	no	17.502	17.437	EPSD	COSMIC;CCLE	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	O95644	NFATC1	P27361	MAPK3	S403	A397S	397	Missense	distal	-6	no	17.502	17.818	EPSD	COSMIC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	O95644	NFATC1	P27361	MAPK3	S409	P410L	410	Missense	proximal	1	no	14.915	5.877	EPSD	COSMIC	9.358	Loss
CMGC_MAPK_ERK1_MAPK3_ST	O95644	NFATC1	P27361	MAPK3	S409	A414T	414	Missense	distal	5	no	14.915	15.035	EPSD	COSMIC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	O95644	NFATC1	P27361	MAPK3	S409	S406F	406	Missense	distal	-3	no	14.915	14.774	EPSD	COSMIC;CCLE	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	O95644	NFATC1	P27361	MAPK3	S409	P413H	413	Missense	distal	4	no	14.915	14.824	EPSD	COSMIC;CCLE	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	O95644	NFATC1	P27361	MAPK3	T504	T505P	505	Missense	proximal	1	no	6.704	15.581	EPSD	COSMIC	9.358	Gain
CMGC_MAPK_ERK1_MAPK3_ST	O95644	NFATC1	P27361	MAPK3	S506	T505P	505	Missense	proximal	-1	no	10.807	10.843	EPSD	COSMIC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	O95644	NFATC1	P27361	MAPK3	S675	C679W	679	Missense	distal	4	no	10.462	10.352	EPSD	COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	O95644	NFATC1	P27361	MAPK3	S723	V718L	718	Missense	distal	-5	no	17.323	17.339	EPSD	COSMIC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	O95644	NFATC1	P27361	MAPK3	S723	G716V	716	Missense	distal	-7	no	17.323	17.434	EPSD	COSMIC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	O95644	NFATC1	P27361	MAPK3	S723	L725F	725	Missense	proximal	2	no	17.323	17.296	EPSD	COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	O95644	NFATC1	P27361	MAPK3	S723	P724L	724	Missense	proximal	1	no	17.323	8.285	EPSD	COSMIC	9.358	Loss
CMGC_MAPK_ERK1_MAPK3_ST	O95644	NFATC1	P27361	MAPK3	S723	R727K	727	Missense	distal	4	no	17.323	17.331	EPSD	COSMIC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	O95644	NFATC1	P27361	MAPK3	S723	P717L	717	Missense	distal	-6	no	17.323	17.076	EPSD	COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	O95644	NFATC1	P27361	MAPK3	S765	P762L	762	Missense	distal	-3	no	17.045	16.961	EPSD	COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	O95644	NFATC1	P27361	MAPK3	S765	P762S	762	Missense	distal	-3	no	17.045	17.037	EPSD	COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	O95644	NFATC1	P27361	MAPK3	S765	D770N	770	Missense	distal	5	no	17.045	16.965	EPSD	COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	O95644	NFATC1	P27361	MAPK3	S765	A760T	760	Missense	distal	-5	no	17.045	17.128	EPSD	COSMIC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	O95644	NFATC1	P27361	MAPK3	S765	D770Y	770	Missense	distal	5	no	17.045	16.871	EPSD	COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	O95644	NFATC1	P27361	MAPK3	S765	V764M	764	Missense	proximal	-1	no	17.045	16.974	EPSD	COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	O95644	NFATC1	P27361	MAPK3	S772	A775S	775	Missense	distal	3	no	16.186	16.230	EPSD	COSMIC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	O95644	NFATC1	P27361	MAPK3	S772	D770N	770	Missense	proximal	-2	no	16.186	15.773	EPSD	COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	O95644	NFATC1	P27361	MAPK3	S772	D770Y	770	Missense	proximal	-2	no	16.186	16.484	EPSD	COSMIC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	O95644	NFATC1	P27361	MAPK3	S782	A781V	781	Missense	proximal	-1	no	16.229	16.278	EPSD	COSMIC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	O95644	NFATC1	P27361	MAPK3	S782	A775S	775	Missense	distal	-7	no	16.229	16.079	EPSD	COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	O95644	NFATC1	P27361	MAPK3	S813	P806L	806	Missense	distal	-7	no	19.567	19.675	EPSD	COSMIC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	O95644	NFATC1	P27361	MAPK3	S813	P819L	819	Missense	distal	6	no	19.567	19.341	EPSD	COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	O95644	NFATC1	P27361	MAPK3	S813	G815V	815	Missense	proximal	2	no	19.567	19.559	EPSD	COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	O95644	NFATC1	P27361	MAPK3	S813	S813L	813	Missense	central	0	yes	19.567	0.000	EPSD	COSMIC	9.358	Loss
CMGC_MAPK_ERK1_MAPK3_ST	O95644	NFATC1	P27361	MAPK3	S887	T881M	881	Missense	distal	-6	no	15.808	15.555	EPSD	COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	O95644	NFATC1	P27361	MAPK3	S887	R893W	893	Missense	distal	6	no	15.808	14.985	EPSD	COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	O95644	NFATC1	P27361	MAPK3	S887	R883H	883	Missense	distal	-4	no	15.808	15.822	EPSD	COSMIC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	O95644	NFATC1	P27361	MAPK3	S887	A890V	890	Missense	distal	3	no	15.808	15.815	EPSD	COSMIC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	O95644	NFATC1	P27361	MAPK3	S903	A907V	907	Missense	distal	4	no	16.396	16.504	EPSD	COSMIC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P04637	TP53	P27361	MAPK3	S15	E11Q	11	Missense	distal	-4	no	12.832	12.789	EPSD;PhosphoSitePlus	COSMIC;GDSC;CCLE	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P04637	TP53	P27361	MAPK3	S15	S20L	20	Missense	distal	5	no	12.832	12.561	EPSD;PhosphoSitePlus	COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P04637	TP53	P27361	MAPK3	S15	Q16L	16	Missense	proximal	1	no	12.832	11.738	EPSD;PhosphoSitePlus	COSMIC;GDSC;CCLE	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P04637	TP53	P27361	MAPK3	S15	P13S	13	Missense	proximal	-2	no	12.832	11.756	EPSD;PhosphoSitePlus	COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P04637	TP53	P27361	MAPK3	S15	E17K	17	Missense	proximal	2	no	12.832	12.824	EPSD;PhosphoSitePlus	COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P04637	TP53	P27361	MAPK3	S15	V10I	10	Missense	distal	-5	no	12.832	12.813	EPSD;PhosphoSitePlus	COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P04637	TP53	P27361	MAPK3	S15	P8L	8	Missense	distal	-7	no	12.832	12.939	EPSD;PhosphoSitePlus	COSMIC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P04637	TP53	P27361	MAPK3	S15	P8S	8	Missense	distal	-7	no	12.832	12.794	EPSD;PhosphoSitePlus	COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P04637	TP53	P27361	MAPK3	S15	P13L	13	Missense	proximal	-2	no	12.832	11.448	EPSD;PhosphoSitePlus	COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P04637	TP53	P27361	MAPK3	S15	V10G	10	Missense	distal	-5	no	12.832	12.864	EPSD;PhosphoSitePlus	COSMIC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P04637	TP53	P27361	MAPK3	S15	T18A	18	Missense	distal	3	no	12.832	12.802	EPSD;PhosphoSitePlus	COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P04637	TP53	P27361	MAPK3	S15	F19S	19	Missense	distal	4	no	12.832	13.246	EPSD;PhosphoSitePlus	COSMIC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P04637	TP53	P27361	MAPK3	S15	E17V	17	Missense	proximal	2	no	12.832	12.815	EPSD;PhosphoSitePlus	COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P04637	TP53	P27361	MAPK3	S15	S9G	9	Missense	distal	-6	no	12.832	12.770	EPSD;PhosphoSitePlus	COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P04637	TP53	P27361	MAPK3	S15	T18I	18	Missense	distal	3	no	12.832	12.794	EPSD;PhosphoSitePlus	COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P04637	TP53	P27361	MAPK3	S15	T18K	18	Missense	distal	3	no	12.832	12.822	EPSD;PhosphoSitePlus	COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P04637	TP53	P27361	MAPK3	S15	T18R	18	Missense	distal	3	no	12.832	12.823	EPSD;PhosphoSitePlus	COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P04637	TP53	P27361	MAPK3	S15	S15I	15	Missense	central	0	yes	12.832	0.000	EPSD;PhosphoSitePlus	COSMIC	9.358	Loss
CMGC_MAPK_ERK1_MAPK3_ST	P04637	TP53	P27361	MAPK3	T18	E11Q	11	Missense	distal	-7	no	10.342	10.391	EPSD	COSMIC;GDSC;CCLE	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P04637	TP53	P27361	MAPK3	T18	S20L	20	Missense	proximal	2	no	10.342	10.318	EPSD	COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P04637	TP53	P27361	MAPK3	T18	Q16L	16	Missense	proximal	-2	no	10.342	10.721	EPSD	COSMIC;GDSC;CCLE	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P04637	TP53	P27361	MAPK3	T18	P13S	13	Missense	distal	-5	no	10.342	10.347	EPSD	COSMIC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P04637	TP53	P27361	MAPK3	T18	E17K	17	Missense	proximal	-1	no	10.342	10.311	EPSD	COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P04637	TP53	P27361	MAPK3	T18	P13L	13	Missense	distal	-5	no	10.342	10.287	EPSD	COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P04637	TP53	P27361	MAPK3	T18	T18A	18	Missense	central	0	yes	10.342	0.000	EPSD	COSMIC	9.358	Loss
CMGC_MAPK_ERK1_MAPK3_ST	P04637	TP53	P27361	MAPK3	T18	F19S	19	Missense	proximal	1	no	10.342	7.502	EPSD	COSMIC	9.358	Loss
CMGC_MAPK_ERK1_MAPK3_ST	P04637	TP53	P27361	MAPK3	T18	E17V	17	Missense	proximal	-1	no	10.342	10.282	EPSD	COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P04637	TP53	P27361	MAPK3	T18	T18I	18	Missense	central	0	yes	10.342	0.000	EPSD	COSMIC	9.358	Loss
CMGC_MAPK_ERK1_MAPK3_ST	P04637	TP53	P27361	MAPK3	T18	T18K	18	Missense	central	0	yes	10.342	0.000	EPSD	COSMIC	9.358	Loss
CMGC_MAPK_ERK1_MAPK3_ST	P04637	TP53	P27361	MAPK3	T18	T18R	18	Missense	central	0	yes	10.342	0.000	EPSD	COSMIC	9.358	Loss
CMGC_MAPK_ERK1_MAPK3_ST	P04637	TP53	P27361	MAPK3	T18	S15I	15	Missense	distal	-3	no	10.342	10.230	EPSD	COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P04637	TP53	P27361	MAPK3	S20	S20L	20	Missense	central	0	yes	10.750	0.000	EPSD	COSMIC	9.358	Loss
CMGC_MAPK_ERK1_MAPK3_ST	P04637	TP53	P27361	MAPK3	S20	Q16L	16	Missense	distal	-4	no	10.750	10.677	EPSD	COSMIC;GDSC;CCLE	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P04637	TP53	P27361	MAPK3	S20	P13S	13	Missense	distal	-7	no	10.750	10.713	EPSD	COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P04637	TP53	P27361	MAPK3	S20	E17K	17	Missense	distal	-3	no	10.750	10.719	EPSD	COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P04637	TP53	P27361	MAPK3	S20	P13L	13	Missense	distal	-7	no	10.750	10.858	EPSD	COSMIC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P04637	TP53	P27361	MAPK3	S20	L26P	26	Missense	distal	6	no	10.750	10.977	EPSD	COSMIC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P04637	TP53	P27361	MAPK3	S20	T18A	18	Missense	proximal	-2	no	10.750	9.385	EPSD	COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P04637	TP53	P27361	MAPK3	S20	F19S	19	Missense	proximal	-1	no	10.750	10.955	EPSD	COSMIC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P04637	TP53	P27361	MAPK3	S20	E17V	17	Missense	distal	-3	no	10.750	10.698	EPSD	COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P04637	TP53	P27361	MAPK3	S20	P27T	27	Missense	distal	7	no	10.750	10.791	EPSD	COSMIC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P04637	TP53	P27361	MAPK3	S20	T18I	18	Missense	proximal	-2	no	10.750	9.898	EPSD	COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P04637	TP53	P27361	MAPK3	S20	T18K	18	Missense	proximal	-2	no	10.750	9.396	EPSD	COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P04637	TP53	P27361	MAPK3	S20	T18R	18	Missense	proximal	-2	no	10.750	10.336	EPSD	COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P04637	TP53	P27361	MAPK3	S20	S15I	15	Missense	distal	-5	no	10.750	10.656	EPSD	COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P04637	TP53	P27361	MAPK3	S33	M40I	40	Missense	distal	7	no	15.325	15.273	EPSD	COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P04637	TP53	P27361	MAPK3	S33	V31I	31	Missense	proximal	-2	no	15.325	15.141	EPSD	COSMIC;GDSC;CCLE	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P04637	TP53	P27361	MAPK3	S33	P36L	36	Missense	distal	3	no	15.325	15.288	EPSD	COSMIC;GDSC;CCLE	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P04637	TP53	P27361	MAPK3	S33	L35F	35	Missense	proximal	2	no	15.325	15.298	EPSD	COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P04637	TP53	P27361	MAPK3	S33	Q38L	38	Missense	distal	5	no	15.325	15.200	EPSD	COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P04637	TP53	P27361	MAPK3	S33	S37T	37	Missense	distal	4	no	15.325	15.212	EPSD	COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P04637	TP53	P27361	MAPK3	S33	L26P	26	Missense	distal	-7	no	15.325	15.218	EPSD	COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P04637	TP53	P27361	MAPK3	S33	P36S	36	Missense	distal	3	no	15.325	15.320	EPSD	COSMIC;GDSC;CCLE	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P04637	TP53	P27361	MAPK3	S33	A39V	39	Missense	distal	6	no	15.325	15.412	EPSD	COSMIC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P04637	TP53	P27361	MAPK3	S33	A39S	39	Missense	distal	6	no	15.325	15.851	EPSD	COSMIC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P04637	TP53	P27361	MAPK3	S33	N30K	30	Missense	distal	-3	no	15.325	15.318	EPSD	COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P04637	TP53	P27361	MAPK3	S33	A39T	39	Missense	distal	6	no	15.325	15.696	EPSD	COSMIC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P04637	TP53	P27361	MAPK3	S33	P27T	27	Missense	distal	-6	no	15.325	15.241	EPSD	COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P04637	TP53	P27361	MAPK3	S33	P36R	36	Missense	distal	3	no	15.325	15.298	EPSD	COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P04637	TP53	P27361	MAPK3	S33	L35R	35	Missense	proximal	2	no	15.325	15.336	EPSD	COSMIC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P04637	TP53	P27361	MAPK3	S33	L35H	35	Missense	proximal	2	no	15.325	15.333	EPSD	COSMIC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P04637	TP53	P27361	MAPK3	S33	L35P	35	Missense	proximal	2	no	15.325	15.347	EPSD	COSMIC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P04637	TP53	P27361	MAPK3	S33	L35I	35	Missense	proximal	2	no	15.325	15.313	EPSD	COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P04637	TP53	P27361	MAPK3	S33	L35V	35	Missense	proximal	2	no	15.325	15.323	EPSD	COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P04637	TP53	P27361	MAPK3	S46	M40I	40	Missense	distal	-6	no	14.562	14.585	EPSD	COSMIC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P04637	TP53	P27361	MAPK3	S46	W53C	53	Missense	distal	7	no	14.562	14.428	EPSD	COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P04637	TP53	P27361	MAPK3	S46	W53G	53	Missense	distal	7	no	14.562	13.955	EPSD	COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P04637	TP53	P27361	MAPK3	S46	S46F	46	Missense	central	0	yes	14.562	0.000	EPSD	COSMIC	9.358	Loss
CMGC_MAPK_ERK1_MAPK3_ST	P04637	TP53	P27361	MAPK3	S46	D49Y	49	Missense	distal	3	no	14.562	14.542	EPSD	COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P04637	TP53	P27361	MAPK3	S46	P47L	47	Missense	proximal	1	no	14.562	5.524	EPSD	COSMIC	9.358	Loss
CMGC_MAPK_ERK1_MAPK3_ST	P04637	TP53	P27361	MAPK3	S46	D49H	49	Missense	distal	3	no	14.562	14.558	EPSD	COSMIC;GDSC;CCLE	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P04637	TP53	P27361	MAPK3	S46	P47S	47	Missense	proximal	1	no	14.562	5.508	EPSD	COSMIC	9.358	Loss
CMGC_MAPK_ERK1_MAPK3_ST	P04637	TP53	P27361	MAPK3	S46	D41N	41	Missense	distal	-5	no	14.562	14.556	EPSD	COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P04637	TP53	P27361	MAPK3	S46	D48H	48	Missense	proximal	2	no	14.562	14.558	EPSD	COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P04637	TP53	P27361	MAPK3	S46	D49N	49	Missense	distal	3	no	14.562	14.551	EPSD	COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P04637	TP53	P27361	MAPK3	S46	M44I	44	Missense	proximal	-2	no	14.562	15.477	EPSD	COSMIC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P04637	TP53	P27361	MAPK3	S46	Q52H	52	Missense	distal	6	no	14.562	14.650	EPSD	COSMIC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P04637	TP53	P27361	MAPK3	S46	D49V	49	Missense	distal	3	no	14.562	14.535	EPSD	COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P04637	TP53	P27361	MAPK3	S46	A39V	39	Missense	distal	-7	no	14.562	14.561	EPSD	COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P04637	TP53	P27361	MAPK3	S46	A39S	39	Missense	distal	-7	no	14.562	14.412	EPSD	COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P04637	TP53	P27361	MAPK3	S46	D42Y	42	Missense	distal	-4	no	14.562	14.494	EPSD	COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P04637	TP53	P27361	MAPK3	S46	M44R	44	Missense	proximal	-2	no	14.562	15.916	EPSD	COSMIC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P04637	TP53	P27361	MAPK3	S46	S46P	46	Missense	central	0	yes	14.562	0.000	EPSD	COSMIC	9.358	Loss
CMGC_MAPK_ERK1_MAPK3_ST	P04637	TP53	P27361	MAPK3	S46	M44V	44	Missense	proximal	-2	no	14.562	15.662	EPSD	COSMIC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P04637	TP53	P27361	MAPK3	S46	L45P	45	Missense	proximal	-1	no	14.562	14.656	EPSD	COSMIC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P04637	TP53	P27361	MAPK3	S46	M44T	44	Missense	proximal	-2	no	14.562	16.330	EPSD	COSMIC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P04637	TP53	P27361	MAPK3	S46	A39T	39	Missense	distal	-7	no	14.562	14.488	EPSD	COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P04637	TP53	P27361	MAPK3	S46	L43F	43	Missense	distal	-3	no	14.562	14.496	EPSD	COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P04637	TP53	P27361	MAPK3	S46	D41H	41	Missense	distal	-5	no	14.562	14.560	EPSD	COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P04637	TP53	P27361	MAPK3	S46	D49E	49	Missense	distal	3	no	14.562	14.559	EPSD	COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P04637	TP53	P27361	MAPK3	S46	D49G	49	Missense	distal	3	no	14.562	14.557	EPSD	COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P04637	TP53	P27361	MAPK3	S46	D48A	48	Missense	proximal	2	no	14.562	14.535	EPSD	COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P04637	TP53	P27361	MAPK3	S46	D48Y	48	Missense	proximal	2	no	14.562	14.552	EPSD	COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P04637	TP53	P27361	MAPK3	S46	D48E	48	Missense	proximal	2	no	14.562	14.564	EPSD	COSMIC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P04637	TP53	P27361	MAPK3	S46	D49I	49	Missense	distal	3	no	14.562	14.521	EPSD	COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P04637	TP53	P27361	MAPK3	T81	P77A	77	Missense	distal	-4	no	16.918	16.814	EPSD	COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P04637	TP53	P27361	MAPK3	T81	A76T	76	Missense	distal	-5	no	16.918	17.002	EPSD	COSMIC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P04637	TP53	P27361	MAPK3	T81	A83T	83	Missense	proximal	2	no	16.918	16.946	EPSD	COSMIC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P04637	TP53	P27361	MAPK3	T81	T81I	81	Missense	central	0	yes	16.918	0.000	EPSD	COSMIC	9.358	Loss
CMGC_MAPK_ERK1_MAPK3_ST	P04637	TP53	P27361	MAPK3	T81	A84V	84	Missense	distal	3	no	16.918	16.925	EPSD	COSMIC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P04637	TP53	P27361	MAPK3	T81	P80L	80	Missense	proximal	-1	no	16.918	16.824	EPSD	COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P04637	TP53	P27361	MAPK3	T81	A86V	86	Missense	distal	5	no	16.918	16.907	EPSD	COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P04637	TP53	P27361	MAPK3	T81	P85S	85	Missense	distal	4	no	16.918	16.967	EPSD	COSMIC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P04637	TP53	P27361	MAPK3	T81	A79T	79	Missense	proximal	-2	no	16.918	18.283	EPSD	COSMIC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P04637	TP53	P27361	MAPK3	T81	A84G	84	Missense	distal	3	no	16.918	16.947	EPSD	COSMIC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P04637	TP53	P27361	MAPK3	T81	A78V	78	Missense	distal	-3	no	16.918	16.938	EPSD	COSMIC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P04637	TP53	P27361	MAPK3	T81	A78S	78	Missense	distal	-3	no	16.918	17.010	EPSD	COSMIC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P04637	TP53	P27361	MAPK3	T81	P87L	87	Missense	distal	6	no	16.918	16.692	EPSD	COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P04637	TP53	P27361	MAPK3	T81	P85L	85	Missense	distal	4	no	16.918	16.764	EPSD	COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P04637	TP53	P27361	MAPK3	T81	P82S	82	Missense	proximal	1	no	16.918	7.865	EPSD	COSMIC	9.358	Loss
CMGC_MAPK_ERK1_MAPK3_ST	P04637	TP53	P27361	MAPK3	T81	P77S	77	Missense	distal	-4	no	16.918	16.946	EPSD	COSMIC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P04637	TP53	P27361	MAPK3	T81	P80S	80	Missense	proximal	-1	no	16.918	16.913	EPSD	COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P04637	TP53	P27361	MAPK3	T81	A84T	84	Missense	distal	3	no	16.918	16.949	EPSD	COSMIC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P04637	TP53	P27361	MAPK3	T81	A83E	83	Missense	proximal	2	no	16.918	16.948	EPSD	COSMIC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P04637	TP53	P27361	MAPK3	T81	P85T	85	Missense	distal	4	no	16.918	16.854	EPSD	COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P04637	TP53	P27361	MAPK3	T81	P75S	75	Missense	distal	-6	no	16.918	17.003	EPSD	COSMIC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P04637	TP53	P27361	MAPK3	T81	A76V	76	Missense	distal	-5	no	16.918	16.941	EPSD	COSMIC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P04637	TP53	P27361	MAPK3	T81	P75R	75	Missense	distal	-6	no	16.918	16.843	EPSD	COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P04637	TP53	P27361	MAPK3	T81	P87H	87	Missense	distal	6	no	16.918	16.825	EPSD	COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P04637	TP53	P27361	MAPK3	T81	P87T	87	Missense	distal	6	no	16.918	16.893	EPSD	COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P04637	TP53	P27361	MAPK3	T81	P87S	87	Missense	distal	6	no	16.918	17.048	EPSD	COSMIC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P04637	TP53	P27361	MAPK3	T81	P87R	87	Missense	distal	6	no	16.918	16.806	EPSD	COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P04637	TP53	P27361	MAPK3	T81	P87C	87	Missense	distal	6	no	16.918	16.181	EPSD	COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P04637	TP53	P27361	MAPK3	T81	A86E	86	Missense	distal	5	no	16.918	17.150	EPSD	COSMIC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P04637	TP53	P27361	MAPK3	T81	A86S	86	Missense	distal	5	no	16.918	17.174	EPSD	COSMIC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P04637	TP53	P27361	MAPK3	T81	A83V	83	Missense	proximal	2	no	16.918	16.932	EPSD	COSMIC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P04637	TP53	P27361	MAPK3	S106	Q104H	104	Missense	proximal	-2	no	8.918	9.454	EPSD	COSMIC	9.358	Gain
CMGC_MAPK_ERK1_MAPK3_ST	P04637	TP53	P27361	MAPK3	S127	C124W	124	Missense	distal	-3	no	16.318	16.290	EPSD	COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P04637	TP53	P27361	MAPK3	S127	C124F	124	Missense	distal	-3	no	16.318	16.354	EPSD	COSMIC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P04637	TP53	P27361	MAPK3	S127	C124S	124	Missense	distal	-3	no	16.318	16.496	EPSD	COSMIC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P04637	TP53	P27361	MAPK3	S127	S127A	127	Missense	central	0	yes	16.318	0.000	EPSD	COSMIC	9.358	Loss
CMGC_MAPK_ERK1_MAPK3_ST	P04637	TP53	P27361	MAPK3	S127	S127L	127	Missense	central	0	yes	16.318	0.000	EPSD	COSMIC	9.358	Loss
CMGC_MAPK_ERK1_MAPK3_ST	P04637	TP53	P27361	MAPK3	S127	C124T	124	Missense	distal	-3	no	16.318	16.465	EPSD	COSMIC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P04637	TP53	P27361	MAPK3	S127	S127I	127	Missense	central	0	yes	16.318	0.000	EPSD	COSMIC	9.358	Loss
CMGC_MAPK_ERK1_MAPK3_ST	P04637	TP53	P27361	MAPK3	S127	S127G	127	Missense	central	0	yes	16.318	0.000	EPSD	COSMIC	9.358	Loss
CMGC_MAPK_ERK1_MAPK3_ST	P04637	TP53	P27361	MAPK3	S127	N131H	131	Missense	distal	4	no	16.318	16.324	EPSD	COSMIC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P04637	TP53	P27361	MAPK3	S127	N131D	131	Missense	distal	4	no	16.318	16.345	EPSD	COSMIC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P04637	TP53	P27361	MAPK3	S127	T125I	125	Missense	proximal	-2	no	16.318	15.465	EPSD	COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P04637	TP53	P27361	MAPK3	S127	F134I	134	Missense	distal	7	no	16.318	16.225	EPSD	COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P04637	TP53	P27361	MAPK3	S127	K120T	120	Missense	distal	-7	no	16.318	16.311	EPSD	COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P04637	TP53	P27361	MAPK3	S127	F134S	134	Missense	distal	7	no	16.318	15.827	EPSD	COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P04637	TP53	P27361	MAPK3	S127	T125K	125	Missense	proximal	-2	no	16.318	14.963	EPSD	COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P04637	TP53	P27361	MAPK3	S127	M133I	133	Missense	distal	6	no	16.318	16.397	EPSD	COSMIC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P04637	TP53	P27361	MAPK3	S127	N131K	131	Missense	distal	4	no	16.318	16.326	EPSD	COSMIC;CCLE	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P04637	TP53	P27361	MAPK3	S127	P128S	128	Missense	proximal	1	no	16.318	7.264	EPSD	COSMIC	9.358	Loss
CMGC_MAPK_ERK1_MAPK3_ST	P04637	TP53	P27361	MAPK3	S127	M133L	133	Missense	distal	6	no	16.318	16.610	EPSD	COSMIC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P04637	TP53	P27361	MAPK3	S127	A129T	129	Missense	proximal	2	no	16.318	16.345	EPSD	COSMIC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P04637	TP53	P27361	MAPK3	S127	T123I	123	Missense	distal	-4	no	16.318	16.217	EPSD	COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P04637	TP53	P27361	MAPK3	S127	A129G	129	Missense	proximal	2	no	16.318	16.340	EPSD	COSMIC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P04637	TP53	P27361	MAPK3	S127	K132W	132	Missense	distal	5	no	16.318	15.858	EPSD	COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P04637	TP53	P27361	MAPK3	S127	A129V	129	Missense	proximal	2	no	16.318	16.331	EPSD	COSMIC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P04637	TP53	P27361	MAPK3	S127	P128A	128	Missense	proximal	1	no	16.318	7.078	EPSD	COSMIC	9.358	Loss
CMGC_MAPK_ERK1_MAPK3_ST	P04637	TP53	P27361	MAPK3	S127	L130I	130	Missense	distal	3	no	16.318	16.298	EPSD	COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P04637	TP53	P27361	MAPK3	S127	S121F	121	Missense	distal	-6	no	16.318	15.851	EPSD	COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P04637	TP53	P27361	MAPK3	S127	A129D	129	Missense	proximal	2	no	16.318	16.345	EPSD	COSMIC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P04637	TP53	P27361	MAPK3	S127	K120Q	120	Missense	distal	-7	no	16.318	16.316	EPSD	COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P04637	TP53	P27361	MAPK3	S127	T125S	125	Missense	proximal	-2	no	16.318	16.228	EPSD	COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P04637	TP53	P27361	MAPK3	S127	P128L	128	Missense	proximal	1	no	16.318	7.280	EPSD	COSMIC	9.358	Loss
CMGC_MAPK_ERK1_MAPK3_ST	P04637	TP53	P27361	MAPK3	S127	V122L	122	Missense	distal	-5	no	16.318	16.334	EPSD	COSMIC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P04637	TP53	P27361	MAPK3	S127	C124L	124	Missense	distal	-3	no	16.318	16.420	EPSD	COSMIC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P04637	TP53	P27361	MAPK3	S127	N131T	131	Missense	distal	4	no	16.318	16.351	EPSD	COSMIC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P04637	TP53	P27361	MAPK3	S127	M133V	133	Missense	distal	6	no	16.318	16.528	EPSD	COSMIC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P04637	TP53	P27361	MAPK3	T150	P151N	151	Missense	proximal	1	no	12.555	-1.533	EPSD	COSMIC	9.358	Loss
CMGC_MAPK_ERK1_MAPK3_ST	P04637	TP53	P27361	MAPK3	T150	P152A	152	Missense	proximal	2	no	12.555	12.518	EPSD	COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P04637	TP53	P27361	MAPK3	T150	P152T	152	Missense	proximal	2	no	12.555	12.546	EPSD	COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P04637	TP53	P27361	MAPK3	T150	P152H	152	Missense	proximal	2	no	12.555	12.542	EPSD	COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P04637	TP53	P27361	MAPK3	T150	P153T	153	Missense	distal	3	no	12.555	12.537	EPSD	COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P04637	TP53	P27361	MAPK3	T150	V147I	147	Missense	distal	-3	no	12.555	12.516	EPSD	COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P04637	TP53	P27361	MAPK3	T150	P153L	153	Missense	distal	3	no	12.555	12.519	EPSD	COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P04637	TP53	P27361	MAPK3	T150	V147D	147	Missense	distal	-3	no	12.555	12.605	EPSD	COSMIC;GDSC;CCLE	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P04637	TP53	P27361	MAPK3	T150	S149P	149	Missense	proximal	-1	no	12.555	12.561	EPSD	COSMIC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P04637	TP53	P27361	MAPK3	T150	P152K	152	Missense	proximal	2	no	12.555	12.541	EPSD	COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P04637	TP53	P27361	MAPK3	T150	P153S	153	Missense	distal	3	no	12.555	12.550	EPSD	COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P04637	TP53	P27361	MAPK3	T150	G154C	154	Missense	distal	4	no	12.555	12.212	EPSD	COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P04637	TP53	P27361	MAPK3	T150	S149F	149	Missense	proximal	-1	no	12.555	12.351	EPSD	COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P04637	TP53	P27361	MAPK3	T150	G154D	154	Missense	distal	4	no	12.555	12.596	EPSD	COSMIC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P04637	TP53	P27361	MAPK3	T150	V157I	157	Missense	distal	7	no	12.555	12.636	EPSD	COSMIC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P04637	TP53	P27361	MAPK3	T150	W146R	146	Missense	distal	-4	no	12.555	12.763	EPSD	COSMIC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P04637	TP53	P27361	MAPK3	T150	Q144R	144	Missense	distal	-6	no	12.555	12.546	EPSD	COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P04637	TP53	P27361	MAPK3	T150	D148V	148	Missense	proximal	-2	no	12.555	12.508	EPSD	COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P04637	TP53	P27361	MAPK3	T150	S149Y	149	Missense	proximal	-1	no	12.555	12.479	EPSD	COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P04637	TP53	P27361	MAPK3	T150	T150I	150	Missense	central	0	yes	12.555	0.000	EPSD	COSMIC	9.358	Loss
CMGC_MAPK_ERK1_MAPK3_ST	P04637	TP53	P27361	MAPK3	T150	S149T	149	Missense	proximal	-1	no	12.555	12.525	EPSD	COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P04637	TP53	P27361	MAPK3	T150	W146G	146	Missense	distal	-4	no	12.555	12.801	EPSD	COSMIC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P04637	TP53	P27361	MAPK3	T150	L145M	145	Missense	distal	-5	no	12.555	12.497	EPSD	COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P04637	TP53	P27361	MAPK3	T150	V143L	143	Missense	distal	-7	no	12.555	12.551	EPSD	COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P04637	TP53	P27361	MAPK3	T150	R156S	156	Missense	distal	6	no	12.555	12.797	EPSD	COSMIC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P04637	TP53	P27361	MAPK3	T150	D148E	148	Missense	proximal	-2	no	12.555	12.516	EPSD	COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P04637	TP53	P27361	MAPK3	T150	V147F	147	Missense	distal	-3	no	12.555	12.486	EPSD	COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P04637	TP53	P27361	MAPK3	T150	T155A	155	Missense	distal	5	no	12.555	12.436	EPSD	COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P04637	TP53	P27361	MAPK3	T150	V147E	147	Missense	distal	-3	no	12.555	12.608	EPSD	COSMIC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P04637	TP53	P27361	MAPK3	T150	G154I	154	Missense	distal	4	no	12.555	12.375	EPSD	COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P04637	TP53	P27361	MAPK3	T150	D148G	148	Missense	proximal	-2	no	12.555	12.046	EPSD	COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P04637	TP53	P27361	MAPK3	T150	Q144K	144	Missense	distal	-6	no	12.555	12.548	EPSD	COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P04637	TP53	P27361	MAPK3	T150	V147A	147	Missense	distal	-3	no	12.555	12.536	EPSD	COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P04637	TP53	P27361	MAPK3	T150	L145V	145	Missense	distal	-5	no	12.555	12.539	EPSD	COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P04637	TP53	P27361	MAPK3	T150	T150K	150	Missense	central	0	yes	12.555	0.000	EPSD	COSMIC	9.358	Loss
CMGC_MAPK_ERK1_MAPK3_ST	P04637	TP53	P27361	MAPK3	T150	P153H	153	Missense	distal	3	no	12.555	12.536	EPSD	COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P04637	TP53	P27361	MAPK3	T150	V157E	157	Missense	distal	7	no	12.555	12.341	EPSD	COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P04637	TP53	P27361	MAPK3	T150	T155S	155	Missense	distal	5	no	12.555	12.691	EPSD	COSMIC;CCLE	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P04637	TP53	P27361	MAPK3	T150	D148H	148	Missense	proximal	-2	no	12.555	12.934	EPSD	COSMIC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P04637	TP53	P27361	MAPK3	T150	P153A	153	Missense	distal	3	no	12.555	12.507	EPSD	COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P04637	TP53	P27361	MAPK3	T150	T150R	150	Missense	central	0	yes	12.555	0.000	EPSD	COSMIC	9.358	Loss
CMGC_MAPK_ERK1_MAPK3_ST	P04637	TP53	P27361	MAPK3	T150	T155L	155	Missense	distal	5	no	12.555	12.420	EPSD	COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P04637	TP53	P27361	MAPK3	T150	G154A	154	Missense	distal	4	no	12.555	12.385	EPSD	COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P04637	TP53	P27361	MAPK3	T150	T150A	150	Missense	central	0	yes	12.555	0.000	EPSD	COSMIC	9.358	Loss
CMGC_MAPK_ERK1_MAPK3_ST	P04637	TP53	P27361	MAPK3	T150	W146C	146	Missense	distal	-4	no	12.555	12.602	EPSD	COSMIC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P04637	TP53	P27361	MAPK3	T150	P153F	153	Missense	distal	3	no	12.555	12.486	EPSD	COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P04637	TP53	P27361	MAPK3	T150	D148Y	148	Missense	proximal	-2	no	12.555	12.853	EPSD	COSMIC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P04637	TP53	P27361	MAPK3	T150	G154R	154	Missense	distal	4	no	12.555	12.569	EPSD	COSMIC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P04637	TP53	P27361	MAPK3	S313	S314F	314	Missense	proximal	1	no	7.097	9.937	EPSD	COSMIC	9.358	Gain
CMGC_MAPK_ERK1_MAPK3_ST	P04637	TP53	P27361	MAPK3	S314	S315P	315	Missense	proximal	1	no	7.190	16.244	EPSD	COSMIC	9.358	Gain
CMGC_MAPK_ERK1_MAPK3_ST	P04637	TP53	P27361	MAPK3	S315	N310T	310	Missense	distal	-5	no	16.542	16.567	EPSD	COSMIC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P04637	TP53	P27361	MAPK3	S315	Q317R	317	Missense	proximal	2	no	16.542	16.551	EPSD	COSMIC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P04637	TP53	P27361	MAPK3	S315	P309S	309	Missense	distal	-6	no	16.542	16.626	EPSD	COSMIC;GDSC;CCLE	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P04637	TP53	P27361	MAPK3	S315	K319E	319	Missense	distal	4	no	16.542	16.580	EPSD	COSMIC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P04637	TP53	P27361	MAPK3	S315	P322L	322	Missense	distal	7	no	16.542	16.734	EPSD	COSMIC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P04637	TP53	P27361	MAPK3	S315	K320N	320	Missense	distal	5	no	16.542	16.572	EPSD	COSMIC;GDSC;CCLE	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P04637	TP53	P27361	MAPK3	S315	N310L	310	Missense	distal	-5	no	16.542	16.523	EPSD	COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P04637	TP53	P27361	MAPK3	S315	T312S	312	Missense	distal	-3	no	16.542	16.572	EPSD	COSMIC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P04637	TP53	P27361	MAPK3	S315	N311Y	311	Missense	distal	-4	no	16.542	16.500	EPSD	COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P04637	TP53	P27361	MAPK3	S315	P322R	322	Missense	distal	7	no	16.542	16.634	EPSD	COSMIC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P04637	TP53	P27361	MAPK3	S315	N311K	311	Missense	distal	-4	no	16.542	16.519	EPSD	COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P04637	TP53	P27361	MAPK3	S315	Q317K	317	Missense	proximal	2	no	16.542	16.548	EPSD	COSMIC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P04637	TP53	P27361	MAPK3	S315	S315P	315	Missense	central	0	yes	16.542	0.000	EPSD	COSMIC	9.358	Loss
CMGC_MAPK_ERK1_MAPK3_ST	P04637	TP53	P27361	MAPK3	S315	N310H	310	Missense	distal	-5	no	16.542	16.546	EPSD	COSMIC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P04637	TP53	P27361	MAPK3	S315	S314C	314	Missense	proximal	-1	no	16.542	16.315	EPSD	COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P04637	TP53	P27361	MAPK3	S315	P318A	318	Missense	distal	3	no	16.542	16.493	EPSD	COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P04637	TP53	P27361	MAPK3	S315	P316L	316	Missense	proximal	1	no	16.542	7.504	EPSD	COSMIC	9.358	Loss
CMGC_MAPK_ERK1_MAPK3_ST	P04637	TP53	P27361	MAPK3	S315	L308M	308	Missense	distal	-7	no	16.542	16.602	EPSD	COSMIC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P04637	TP53	P27361	MAPK3	S315	S313C	313	Missense	proximal	-2	no	16.542	14.102	EPSD	COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P04637	TP53	P27361	MAPK3	S315	N311H	311	Missense	distal	-4	no	16.542	16.540	EPSD	COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P04637	TP53	P27361	MAPK3	S315	L308V	308	Missense	distal	-7	no	16.542	16.546	EPSD	COSMIC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P04637	TP53	P27361	MAPK3	S315	S314F	314	Missense	proximal	-1	no	16.542	16.338	EPSD	COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P04637	TP53	P27361	MAPK3	S315	K319R	319	Missense	distal	4	no	16.542	16.534	EPSD	COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P04637	TP53	P27361	MAPK3	S315	T312A	312	Missense	distal	-3	no	16.542	16.480	EPSD	COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P04637	TP53	P27361	MAPK3	S315	N310D	310	Missense	distal	-5	no	16.542	16.548	EPSD	COSMIC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P04637	TP53	P27361	MAPK3	S315	N311D	311	Missense	distal	-4	no	16.542	16.568	EPSD	COSMIC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P04637	TP53	P27361	MAPK3	S315	P309R	309	Missense	distal	-6	no	16.542	16.466	EPSD	COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P04637	TP53	P27361	MAPK3	S315	S313N	313	Missense	proximal	-2	no	16.542	15.597	EPSD	COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P04637	TP53	P27361	MAPK3	S315	Q317P	317	Missense	proximal	2	no	16.542	16.562	EPSD	COSMIC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P04637	TP53	P27361	MAPK3	S315	P316S	316	Missense	proximal	1	no	16.542	7.488	EPSD	COSMIC	9.358	Loss
CMGC_MAPK_ERK1_MAPK3_ST	P04637	TP53	P27361	MAPK3	S366	S367F	367	Missense	proximal	1	no	8.875	11.714	EPSD	COSMIC	9.358	Gain
CMGC_MAPK_ERK1_MAPK3_ST	P04637	TP53	P27361	MAPK3	S366	A364D	364	Missense	proximal	-2	no	8.875	9.619	EPSD	COSMIC	9.358	Gain
CMGC_MAPK_ERK1_MAPK3_ST	P04637	TP53	P27361	MAPK3	S366	A364T	364	Missense	proximal	-2	no	8.875	10.240	EPSD	COSMIC	9.358	Gain
CMGC_MAPK_ERK1_MAPK3_ST	P04637	TP53	P27361	MAPK3	S367	S367F	367	Missense	central	0	yes	10.558	0.000	EPSD	COSMIC	9.358	Loss
CMGC_MAPK_ERK1_MAPK3_ST	P04637	TP53	P27361	MAPK3	S367	K370N	370	Missense	distal	3	no	10.558	10.561	EPSD	COSMIC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P04637	TP53	P27361	MAPK3	S367	G361E	361	Missense	distal	-6	no	10.558	10.604	EPSD	COSMIC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P04637	TP53	P27361	MAPK3	S367	A364D	364	Missense	distal	-3	no	10.558	10.627	EPSD	COSMIC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P04637	TP53	P27361	MAPK3	S367	H365Y	365	Missense	proximal	-2	no	10.558	10.477	EPSD	COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P04637	TP53	P27361	MAPK3	S367	G360A	360	Missense	distal	-7	no	10.558	10.670	EPSD	COSMIC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P04637	TP53	P27361	MAPK3	S367	A364T	364	Missense	distal	-3	no	10.558	10.620	EPSD	COSMIC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P04637	TP53	P27361	MAPK3	S367	S366A	366	Missense	proximal	-1	no	10.558	10.425	EPSD	COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P04637	TP53	P27361	MAPK3	S367	G361R	361	Missense	distal	-6	no	10.558	10.460	EPSD	COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P04637	TP53	P27361	MAPK3	S367	K370Q	370	Missense	distal	3	no	10.558	10.560	EPSD	COSMIC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P04637	TP53	P27361	MAPK3	S367	K373R	373	Missense	distal	6	no	10.558	10.524	EPSD	COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P04637	TP53	P27361	MAPK3	S367	G374S	374	Missense	distal	7	no	10.558	10.419	EPSD	COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P04637	TP53	P27361	MAPK3	S367	S371P	371	Missense	distal	4	no	10.558	10.509	EPSD	COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P04637	TP53	P27361	MAPK3	S376	K370N	370	Missense	distal	-6	no	10.149	10.185	EPSD	COSMIC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P04637	TP53	P27361	MAPK3	S376	L383F	383	Missense	distal	7	no	10.149	10.370	EPSD	COSMIC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P04637	TP53	P27361	MAPK3	S376	R379H	379	Missense	distal	3	no	10.149	10.157	EPSD	COSMIC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P04637	TP53	P27361	MAPK3	S376	H380Y	380	Missense	distal	4	no	10.149	10.073	EPSD	COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P04637	TP53	P27361	MAPK3	S376	T377I	377	Missense	proximal	1	no	10.149	9.519	EPSD	COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P04637	TP53	P27361	MAPK3	S376	S378F	378	Missense	proximal	2	no	10.149	10.099	EPSD	COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P04637	TP53	P27361	MAPK3	S376	K370Q	370	Missense	distal	-6	no	10.149	10.156	EPSD	COSMIC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P04637	TP53	P27361	MAPK3	S376	K381N	381	Missense	distal	5	no	10.149	10.179	EPSD	COSMIC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P04637	TP53	P27361	MAPK3	S376	R379P	379	Missense	distal	3	no	10.149	10.176	EPSD	COSMIC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P04637	TP53	P27361	MAPK3	S376	K373R	373	Missense	distal	-3	no	10.149	10.162	EPSD	COSMIC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P04637	TP53	P27361	MAPK3	S376	S376F	376	Missense	central	0	yes	10.149	0.000	EPSD	COSMIC	9.358	Loss
CMGC_MAPK_ERK1_MAPK3_ST	P04637	TP53	P27361	MAPK3	S376	G374S	374	Missense	proximal	-2	no	10.149	11.189	EPSD	COSMIC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P04637	TP53	P27361	MAPK3	S376	S376A	376	Missense	central	0	yes	10.149	0.000	EPSD	COSMIC	9.358	Loss
CMGC_MAPK_ERK1_MAPK3_ST	P04637	TP53	P27361	MAPK3	S376	S371P	371	Missense	distal	-5	no	10.149	10.144	EPSD	COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P04637	TP53	P27361	MAPK3	T377	S378F	378	Missense	proximal	1	no	8.789	11.628	EPSD	COSMIC	9.358	Gain
CMGC_MAPK_ERK1_MAPK3_ST	P04637	TP53	P27361	MAPK3	S378	L383F	383	Missense	distal	5	no	9.499	9.345	EPSD	COSMIC	9.358	Loss
CMGC_MAPK_ERK1_MAPK3_ST	P04637	TP53	P27361	MAPK3	S378	R379H	379	Missense	proximal	1	no	9.499	11.244	EPSD	COSMIC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P04637	TP53	P27361	MAPK3	S378	S376T	376	Missense	proximal	-2	no	9.499	9.589	EPSD	COSMIC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P04637	TP53	P27361	MAPK3	S378	H380Y	380	Missense	proximal	2	no	9.499	9.493	EPSD	COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P04637	TP53	P27361	MAPK3	S378	T377I	377	Missense	proximal	-1	no	9.499	9.398	EPSD	COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P04637	TP53	P27361	MAPK3	S378	S378F	378	Missense	central	0	yes	9.499	0.000	EPSD	COSMIC	9.358	Loss
CMGC_MAPK_ERK1_MAPK3_ST	P04637	TP53	P27361	MAPK3	S378	K381N	381	Missense	distal	3	no	9.499	9.502	EPSD	COSMIC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P04637	TP53	P27361	MAPK3	S378	R379P	379	Missense	proximal	1	no	9.499	19.000	EPSD	COSMIC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P04637	TP53	P27361	MAPK3	S378	M384I	384	Missense	distal	6	no	9.499	9.579	EPSD	COSMIC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P04637	TP53	P27361	MAPK3	S378	K373R	373	Missense	distal	-5	no	9.499	9.500	EPSD	COSMIC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P04637	TP53	P27361	MAPK3	S378	S376F	376	Missense	proximal	-2	no	9.499	8.199	EPSD	COSMIC	9.358	Loss
CMGC_MAPK_ERK1_MAPK3_ST	P04637	TP53	P27361	MAPK3	S378	G374S	374	Missense	distal	-4	no	9.499	9.538	EPSD	COSMIC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P04637	TP53	P27361	MAPK3	S378	S376A	376	Missense	proximal	-2	no	9.499	8.224	EPSD	COSMIC	9.358	Loss
CMGC_MAPK_ERK1_MAPK3_ST	P04637	TP53	P27361	MAPK3	S378	S371P	371	Missense	distal	-7	no	9.499	9.537	EPSD	COSMIC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P04637	TP53	P27361	MAPK3	S392	P390L	390	Missense	proximal	-2	no	10.933	9.549	PhosphoSitePlus;EPSD	COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P04637	TP53	P27361	MAPK3	S392	S392P	392	Missense	central	0	yes	10.933	0.000	PhosphoSitePlus;EPSD	COSMIC	9.358	Loss
CMGC_MAPK_ERK1_MAPK3_ST	P04637	TP53	P27361	MAPK3	S392	K386N	386	Missense	distal	-6	no	10.933	10.969	PhosphoSitePlus;EPSD	COSMIC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P04637	TP53	P27361	MAPK3	S392	G389E	389	Missense	distal	-3	no	10.933	10.946	PhosphoSitePlus;EPSD	COSMIC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P04637	TP53	P27361	MAPK3	S392	S392L	392	Missense	central	0	yes	10.933	0.000	PhosphoSitePlus;EPSD	COSMIC	9.358	Loss
CMGC_MAPK_ERK1_MAPK3_ST	P04637	TP53	P27361	MAPK3	S392	D391N	391	Missense	proximal	-1	no	10.933	10.931	PhosphoSitePlus;EPSD	COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P04637	TP53	P27361	MAPK3	S392	D391Y	391	Missense	proximal	-1	no	10.933	10.903	PhosphoSitePlus;EPSD	COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P04637	TP53	P27361	MAPK3	S392	G389V	389	Missense	distal	-3	no	10.933	10.893	PhosphoSitePlus;EPSD	COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P27708	CAD	P27361	MAPK3	T504	R500L	500	Missense	distal	-4	no	14.150	14.087	EPSD	COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P27708	CAD	P27361	MAPK3	T504	E507D	507	Missense	distal	3	no	14.150	14.152	EPSD	COSMIC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P27708	CAD	P27361	MAPK3	S690	S691P	691	Missense	proximal	1	no	8.177	17.230	EPSD	COSMIC	9.358	Gain
CMGC_MAPK_ERK1_MAPK3_ST	P27708	CAD	P27361	MAPK3	S980	T981P	981	Missense	proximal	1	no	7.591	16.469	EPSD	COSMIC	9.358	Gain
CMGC_MAPK_ERK1_MAPK3_ST	P27708	CAD	P27361	MAPK3	S1038	P1039L	1039	Missense	proximal	1	no	15.210	6.172	EPSD	COSMIC	9.358	Loss
CMGC_MAPK_ERK1_MAPK3_ST	P27708	CAD	P27361	MAPK3	S1038	S1038F	1038	Missense	central	0	yes	15.210	0.000	EPSD	COSMIC	9.358	Loss
CMGC_MAPK_ERK1_MAPK3_ST	P27708	CAD	P27361	MAPK3	S1038	C1032G	1032	Missense	distal	-6	no	15.210	15.706	EPSD	COSMIC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P27708	CAD	P27361	MAPK3	S1038	S1044L	1044	Missense	distal	6	no	15.210	14.853	EPSD	COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P27708	CAD	P27361	MAPK3	S1222	P1224H	1224	Missense	proximal	2	no	10.154	10.140	EPSD	COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P27708	CAD	P27361	MAPK3	S1222	P1224S	1224	Missense	proximal	2	no	10.154	10.155	EPSD	COSMIC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P27708	CAD	P27361	MAPK3	S1267	A1272V	1272	Missense	distal	5	no	11.697	11.686	EPSD	COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P27708	CAD	P27361	MAPK3	S1267	F1266L	1266	Missense	proximal	-1	no	11.697	11.813	EPSD	COSMIC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P27708	CAD	P27361	MAPK3	S1267	V1263L	1263	Missense	distal	-4	no	11.697	11.709	EPSD	COSMIC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P27708	CAD	P27361	MAPK3	S1267	A1272T	1272	Missense	distal	5	no	11.697	11.817	EPSD	COSMIC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P27708	CAD	P27361	MAPK3	S1407	R1403Q	1403	Missense	distal	-4	no	10.659	10.669	EPSD	COSMIC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P27708	CAD	P27361	MAPK3	S1407	R1404H	1404	Missense	distal	-3	no	10.659	10.665	EPSD	COSMIC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P27708	CAD	P27361	MAPK3	S1407	R1414H	1414	Missense	distal	7	no	10.659	10.626	EPSD	COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P27708	CAD	P27361	MAPK3	S1407	A1400P	1400	Missense	distal	-7	no	10.659	10.547	EPSD	COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P27708	CAD	P27361	MAPK3	S1407	R1403W	1403	Missense	distal	-4	no	10.659	10.451	EPSD	COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P27708	CAD	P27361	MAPK3	S1407	R1414C	1414	Missense	distal	7	no	10.659	11.101	EPSD	COSMIC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P27708	CAD	P27361	MAPK3	T1833	R1839H	1839	Missense	distal	6	no	15.527	15.546	EPSD	COSMIC;GDSC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P27708	CAD	P27361	MAPK3	T1906	G1908C	1908	Missense	proximal	2	no	16.229	16.185	EPSD	COSMIC;GDSC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P27708	CAD	P27361	MAPK3	S1915	H1919Y	1919	Missense	distal	4	no	15.217	15.142	EPSD	COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P27708	CAD	P27361	MAPK3	S1915	G1908C	1908	Missense	distal	-7	no	15.217	15.449	EPSD	COSMIC;GDSC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q969H0	FBXW7	P27361	MAPK3	T205	F209C	209	Missense	distal	4	no	15.034	14.945	PhosphoSitePlus	COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q969H0	FBXW7	P27361	MAPK3	T205	D211N	211	Missense	distal	6	no	15.034	14.982	PhosphoSitePlus	COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q969H0	FBXW7	P27361	MAPK3	T205	S203L	203	Missense	proximal	-2	no	15.034	14.726	PhosphoSitePlus	COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q969H0	FBXW7	P27361	MAPK3	T205	L199F	199	Missense	distal	-6	no	15.034	14.899	PhosphoSitePlus	COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q969H0	FBXW7	P27361	MAPK3	T205	V200I	200	Missense	distal	-5	no	15.034	15.016	PhosphoSitePlus	COSMIC;GDSC;CCLE	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q969H0	FBXW7	P27361	MAPK3	T205	D211Y	211	Missense	distal	6	no	15.034	14.828	PhosphoSitePlus	COSMIC;GDSC;CCLE	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q969H0	FBXW7	P27361	MAPK3	S349	G345D	345	Missense	distal	-4	no	16.748	16.751	EPSD	COSMIC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q969H0	FBXW7	P27361	MAPK3	S349	A354S	354	Missense	distal	5	no	16.748	17.003	EPSD	COSMIC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q969H0	FBXW7	P27361	MAPK3	S372	H379Y	379	Missense	distal	7	no	15.767	15.884	EPSD	COSMIC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q969H0	FBXW7	P27361	MAPK3	S372	H379P	379	Missense	distal	7	no	15.767	15.707	EPSD	COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q969H0	FBXW7	P27361	MAPK3	S372	R367P	367	Missense	distal	-5	no	15.767	15.807	EPSD	COSMIC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q969H0	FBXW7	P27361	MAPK3	S372	V375M	375	Missense	distal	3	no	15.767	15.742	EPSD	COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q969H0	FBXW7	P27361	MAPK3	S372	H379R	379	Missense	distal	7	no	15.767	15.799	EPSD	COSMIC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q969H0	FBXW7	P27361	MAPK3	S372	K371T	371	Missense	proximal	-1	no	15.767	15.791	EPSD	COSMIC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q969H0	FBXW7	P27361	MAPK3	S372	G378E	378	Missense	distal	6	no	15.767	15.867	EPSD	COSMIC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q969H0	FBXW7	P27361	MAPK3	S372	P373L	373	Missense	proximal	1	no	15.767	6.729	EPSD	COSMIC	9.358	Loss
CMGC_MAPK_ERK1_MAPK3_ST	Q969H0	FBXW7	P27361	MAPK3	S372	E369G	369	Missense	distal	-3	no	15.767	15.754	EPSD	COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q969H0	FBXW7	P27361	MAPK3	S372	R366S	366	Missense	distal	-6	no	15.767	15.927	EPSD	COSMIC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q969H0	FBXW7	P27361	MAPK3	S372	R366T	366	Missense	distal	-6	no	15.767	15.759	EPSD	COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q969H0	FBXW7	P27361	MAPK3	S372	L376S	376	Missense	distal	4	no	15.767	15.970	EPSD	COSMIC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q969H0	FBXW7	P27361	MAPK3	S372	R366M	366	Missense	distal	-6	no	15.767	15.505	EPSD	COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q969H0	FBXW7	P27361	MAPK3	S688	A685E	685	Missense	distal	-3	no	9.905	9.977	EPSD	COSMIC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q969H0	FBXW7	P27361	MAPK3	S688	A685V	685	Missense	distal	-3	no	9.905	9.925	EPSD	COSMIC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q969H0	FBXW7	P27361	MAPK3	S688	G687V	687	Missense	proximal	-1	no	9.905	9.887	EPSD	COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q969H0	FBXW7	P27361	MAPK3	S688	S688I	688	Missense	central	0	yes	9.905	0.000	EPSD	COSMIC	9.358	Loss
CMGC_MAPK_ERK1_MAPK3_ST	Q969H0	FBXW7	P27361	MAPK3	S688	T692S	692	Missense	distal	4	no	9.905	10.018	EPSD	COSMIC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q969H0	FBXW7	P27361	MAPK3	S688	V686D	686	Missense	proximal	-2	no	9.905	9.953	EPSD	COSMIC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q969H0	FBXW7	P27361	MAPK3	S688	V683M	683	Missense	distal	-5	no	9.905	9.863	EPSD	COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q969H0	FBXW7	P27361	MAPK3	S688	T692I	692	Missense	distal	4	no	9.905	9.677	EPSD	COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q969H0	FBXW7	P27361	MAPK3	S688	R689E	689	Missense	proximal	1	no	9.905	10.158	EPSD	COSMIC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P10275	AR	P27361	MAPK3	T18	A22T	22	Missense	distal	4	no	10.192	10.410	EPSD	COSMIC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P10275	AR	P27361	MAPK3	T18	F23L	23	Missense	distal	5	no	10.192	10.346	EPSD	COSMIC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P10275	AR	P27361	MAPK3	T18	Q24H	24	Missense	distal	6	no	10.192	10.280	EPSD	COSMIC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P10275	AR	P27361	MAPK3	T18	R13W	13	Missense	distal	-5	no	10.192	10.038	EPSD	COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P10275	AR	P27361	MAPK3	T18	G21A	21	Missense	distal	3	no	10.192	10.163	EPSD	COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P10275	AR	P27361	MAPK3	T18	P12A	12	Missense	distal	-6	no	10.192	9.960	EPSD	COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P10275	AR	P27361	MAPK3	S83	Q79E	79	Missense	distal	-4	no	16.226	16.269	EPSD	COSMIC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P10275	AR	P27361	MAPK3	S83	Q86K	86	Missense	distal	3	no	16.226	16.224	EPSD	COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P10275	AR	P27361	MAPK3	S83	E81Q	81	Missense	proximal	-2	no	16.226	16.108	EPSD	COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P10275	AR	P27361	MAPK3	S83	Q90H	90	Missense	distal	7	no	16.226	16.164	EPSD	COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P10275	AR	P27361	MAPK3	S83	Q79R	79	Missense	distal	-4	no	16.226	16.216	EPSD	COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P10275	AR	P27361	MAPK3	S83	P84H	84	Missense	proximal	1	no	16.226	8.470	EPSD	COSMIC	9.358	Loss
CMGC_MAPK_ERK1_MAPK3_ST	P10275	AR	P27361	MAPK3	S96	S96Y	96	Missense	central	0	yes	16.503	0.000	EPSD	COSMIC	9.358	Loss
CMGC_MAPK_ERK1_MAPK3_ST	P10275	AR	P27361	MAPK3	S96	Q90H	90	Missense	distal	-6	no	16.503	16.489	EPSD	COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P10275	AR	P27361	MAPK3	S96	S96F	96	Missense	central	0	yes	16.503	0.000	EPSD	COSMIC	9.358	Loss
CMGC_MAPK_ERK1_MAPK3_ST	P10275	AR	P27361	MAPK3	S258	L257P	257	Missense	proximal	-1	no	15.215	15.310	EPSD	COSMIC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P10275	AR	P27361	MAPK3	S258	R264Q	264	Missense	distal	6	no	15.215	15.146	EPSD	COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P10275	AR	P27361	MAPK3	S258	E252G	252	Missense	distal	-6	no	15.215	15.169	EPSD	COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P10275	AR	P27361	MAPK3	S258	E252K	252	Missense	distal	-6	no	15.215	15.073	EPSD	COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P10275	AR	P27361	MAPK3	S258	E255K	255	Missense	distal	-3	no	15.215	15.184	EPSD	COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P10275	AR	P27361	MAPK3	T282	R280H	280	Missense	proximal	-2	no	14.843	15.016	EPSD	COSMIC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P10275	AR	P27361	MAPK3	T282	E289G	289	Missense	distal	7	no	14.843	14.878	EPSD	COSMIC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P10275	AR	P27361	MAPK3	T282	P276S	276	Missense	distal	-6	no	14.843	14.928	EPSD	COSMIC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P10275	AR	P27361	MAPK3	T282	P283S	283	Missense	proximal	1	no	14.843	5.790	EPSD	COSMIC	9.358	Loss
CMGC_MAPK_ERK1_MAPK3_ST	P10275	AR	P27361	MAPK3	T282	A278T	278	Missense	distal	-4	no	14.843	14.917	EPSD	COSMIC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P10275	AR	P27361	MAPK3	T282	A285D	285	Missense	distal	3	no	14.843	14.877	EPSD	COSMIC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P10275	AR	P27361	MAPK3	T282	A278V	278	Missense	distal	-4	no	14.843	14.823	EPSD	COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P10275	AR	P27361	MAPK3	T282	A285V	285	Missense	distal	3	no	14.843	14.850	EPSD	COSMIC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P10275	AR	P27361	MAPK3	S310	D305N	305	Missense	distal	-5	no	15.424	15.418	EPSD	COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P10275	AR	P27361	MAPK3	S310	S310F	310	Missense	central	0	yes	15.424	0.000	EPSD	COSMIC	9.358	Loss
CMGC_MAPK_ERK1_MAPK3_ST	P10275	AR	P27361	MAPK3	S310	E304K	304	Missense	distal	-6	no	15.424	15.282	EPSD	COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P10275	AR	P27361	MAPK3	S310	T306I	306	Missense	distal	-4	no	15.424	15.322	EPSD	COSMIC;GDSC;CCLE	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P10275	AR	P27361	MAPK3	S310	F312L	312	Missense	proximal	2	no	15.424	15.450	EPSD	COSMIC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P10275	AR	P27361	MAPK3	S426	A430T	430	Missense	distal	4	no	16.776	16.994	EPSD	COSMIC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P10275	AR	P27361	MAPK3	S426	A420E	420	Missense	distal	-6	no	16.776	17.076	EPSD	COSMIC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P10275	AR	P27361	MAPK3	S426	G421V	421	Missense	distal	-5	no	16.776	16.743	EPSD	COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P10275	AR	P27361	MAPK3	S426	A430S	430	Missense	distal	4	no	16.776	17.107	EPSD	COSMIC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P10275	AR	P27361	MAPK3	S426	G421R	421	Missense	distal	-5	no	16.776	16.774	EPSD	COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P10275	AR	P27361	MAPK3	S426	S433L	433	Missense	distal	7	no	16.776	17.046	EPSD	COSMIC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P10275	AR	P27361	MAPK3	S426	S424C	424	Missense	proximal	-2	no	16.776	14.336	EPSD	COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P10275	AR	P27361	MAPK3	S426	S424F	424	Missense	proximal	-2	no	16.776	15.476	EPSD	COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P10275	AR	P27361	MAPK3	S516	P515H	515	Missense	proximal	-1	no	17.503	17.458	EPSD;PhosphoSitePlus	COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P10275	AR	P27361	MAPK3	S516	E523K	523	Missense	distal	7	no	17.503	17.573	EPSD;PhosphoSitePlus	COSMIC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P10275	AR	P27361	MAPK3	S516	P515S	515	Missense	proximal	-1	no	17.503	17.497	EPSD;PhosphoSitePlus	COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P10275	AR	P27361	MAPK3	S651	A646D	646	Missense	distal	-5	no	18.402	18.466	PhosphoSitePlus;EPSD	COSMIC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P10275	AR	P27361	MAPK3	S651	S648R	648	Missense	distal	-3	no	18.402	18.364	PhosphoSitePlus;EPSD	COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P10275	AR	P27361	MAPK3	S651	S648N	648	Missense	distal	-3	no	18.402	18.358	PhosphoSitePlus;EPSD	COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P10275	AR	P27361	MAPK3	S651	E654K	654	Missense	distal	3	no	18.402	18.391	PhosphoSitePlus;EPSD	COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P10275	AR	P27361	MAPK3	S651	S647F	647	Missense	distal	-4	no	18.402	18.213	PhosphoSitePlus;EPSD	COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P10275	AR	P27361	MAPK3	S651	E655D	655	Missense	distal	4	no	18.402	18.382	PhosphoSitePlus;EPSD	COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P10275	AR	P27361	MAPK3	T657	V662A	662	Missense	distal	5	no	9.892	9.904	EPSD	COSMIC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P10275	AR	P27361	MAPK3	T657	E654K	654	Missense	distal	-3	no	9.892	9.861	EPSD	COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P10275	AR	P27361	MAPK3	T657	K659N	659	Missense	proximal	2	no	9.892	9.891	EPSD	COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P10275	AR	P27361	MAPK3	T657	S663L	663	Missense	distal	6	no	9.892	9.536	EPSD	COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P10275	AR	P27361	MAPK3	T657	E655D	655	Missense	proximal	-2	no	9.892	9.931	EPSD	COSMIC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q15750	TAB1	P27361	MAPK3	T376	M372I	372	Missense	distal	-4	no	15.035	15.055	EPSD	COSMIC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q15750	TAB1	P27361	MAPK3	T376	S373G	373	Missense	distal	-3	no	15.035	15.002	EPSD	COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q15750	TAB1	P27361	MAPK3	T376	E371K	371	Missense	distal	-5	no	15.035	15.023	EPSD	COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q15750	TAB1	P27361	MAPK3	S378	M372I	372	Missense	distal	-6	no	16.242	16.265	EPSD	COSMIC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q15750	TAB1	P27361	MAPK3	S378	S373G	373	Missense	distal	-5	no	16.242	16.198	EPSD	COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q15750	TAB1	P27361	MAPK3	S378	E371K	371	Missense	distal	-7	no	16.242	16.293	EPSD	COSMIC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q15750	TAB1	P27361	MAPK3	T431	T435I	435	Missense	distal	4	no	13.827	13.599	EPSD	COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q15750	TAB1	P27361	MAPK3	T431	Q437K	437	Missense	distal	6	no	13.827	13.930	EPSD	COSMIC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q15750	TAB1	P27361	MAPK3	S438	P439L	439	Missense	proximal	1	no	16.253	7.215	PhosphoSitePlus	COSMIC	9.358	Loss
CMGC_MAPK_ERK1_MAPK3_ST	Q15750	TAB1	P27361	MAPK3	S438	T435I	435	Missense	distal	-3	no	16.253	16.172	PhosphoSitePlus	COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q15750	TAB1	P27361	MAPK3	S438	Q437K	437	Missense	proximal	-1	no	16.253	16.279	PhosphoSitePlus	COSMIC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q15750	TAB1	P27361	MAPK3	S492	R489C	489	Missense	distal	-3	no	10.093	9.953	EPSD	COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q15750	TAB1	P27361	MAPK3	S492	Y488C	488	Missense	distal	-4	no	10.093	9.958	EPSD	COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P35228	NOS2	P27361	MAPK3	S37	T40I	40	Missense	distal	3	no	16.647	16.609	EPSD	COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P35228	NOS2	P27361	MAPK3	S37	C33S	33	Missense	distal	-4	no	16.647	16.885	EPSD	COSMIC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P35228	NOS2	P27361	MAPK3	S37	V39E	39	Missense	proximal	2	no	16.647	16.663	EPSD	COSMIC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P35228	NOS2	P27361	MAPK3	S56	P59L	59	Missense	distal	3	no	14.780	14.744	EPSD	COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P35228	NOS2	P27361	MAPK3	S56	S50N	50	Missense	distal	-6	no	14.780	14.658	EPSD	COSMIC;GDSC;CCLE	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P35228	NOS2	P27361	MAPK3	S67	K65M	65	Missense	proximal	-2	no	15.378	14.964	EPSD	COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P35228	NOS2	P27361	MAPK3	S67	K65N	65	Missense	proximal	-2	no	15.378	15.698	EPSD	COSMIC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P35228	NOS2	P27361	MAPK3	S67	G64E	64	Missense	distal	-3	no	15.378	15.391	EPSD	COSMIC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P35228	NOS2	P27361	MAPK3	T77	R83W	83	Missense	distal	6	no	15.836	15.013	EPSD	COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P35228	NOS2	P27361	MAPK3	S80	R83W	83	Missense	distal	3	no	9.549	9.471	EPSD	COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P35228	NOS2	P27361	MAPK3	S81	R83W	83	Missense	proximal	2	no	15.418	15.357	EPSD	COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P35228	NOS2	P27361	MAPK3	S745	Q741H	741	Missense	distal	-4	no	15.298	15.302	PhosphoSitePlus	COSMIC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P35228	NOS2	P27361	MAPK3	S898	L900V	900	Missense	proximal	2	no	9.855	9.853	EPSD	COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P35228	NOS2	P27361	MAPK3	S898	L900M	900	Missense	proximal	2	no	9.855	9.835	EPSD	COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P35228	NOS2	P27361	MAPK3	S898	V891M	891	Missense	distal	-7	no	9.855	9.911	EPSD	COSMIC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P35228	NOS2	P27361	MAPK3	S898	S898Y	898	Missense	central	0	yes	9.855	0.000	EPSD	COSMIC	9.358	Loss
CMGC_MAPK_ERK1_MAPK3_ST	P35228	NOS2	P27361	MAPK3	S898	S892F	892	Missense	distal	-6	no	9.855	9.388	EPSD	COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P13631	RARG	P27361	MAPK3	S36	P37L	37	Missense	proximal	1	no	16.532	7.494	EPSD	COSMIC	9.358	Loss
CMGC_MAPK_ERK1_MAPK3_ST	P13631	RARG	P27361	MAPK3	S43	P37L	37	Missense	distal	-6	no	14.622	14.375	EPSD	COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P13631	RARG	P27361	MAPK3	S43	L49P	49	Missense	distal	6	no	14.622	14.849	EPSD	COSMIC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P13631	RARG	P27361	MAPK3	S43	F46V	46	Missense	distal	3	no	14.622	14.650	EPSD	COSMIC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P13631	RARG	P27361	MAPK3	S77	E72K	72	Missense	distal	-5	no	18.579	18.567	EPSD	COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P13631	RARG	P27361	MAPK3	S77	P82S	82	Missense	distal	5	no	18.579	18.622	EPSD	COSMIC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P13631	RARG	P27361	MAPK3	S77	P83L	83	Missense	distal	6	no	18.579	18.352	EPSD	COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P13631	RARG	P27361	MAPK3	S79	V86I	86	Missense	distal	7	no	17.409	17.489	PhosphoSitePlus	COSMIC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P13631	RARG	P27361	MAPK3	S79	E72K	72	Missense	distal	-7	no	17.409	17.460	PhosphoSitePlus	COSMIC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P13631	RARG	P27361	MAPK3	S79	P82S	82	Missense	distal	3	no	17.409	17.404	PhosphoSitePlus	COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P13631	RARG	P27361	MAPK3	S79	P83L	83	Missense	distal	4	no	17.409	17.254	PhosphoSitePlus	COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P13631	RARG	P27361	MAPK3	S79	R85Q	85	Missense	distal	6	no	17.409	17.340	PhosphoSitePlus	COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P13631	RARG	P27361	MAPK3	S176	S179R	179	Missense	distal	3	no	16.552	16.530	EPSD	COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P13631	RARG	P27361	MAPK3	S179	S179R	179	Missense	central	0	yes	13.070	0.000	EPSD	COSMIC	9.358	Loss
CMGC_MAPK_ERK1_MAPK3_ST	P13631	RARG	P27361	MAPK3	S426	G430S	430	Missense	distal	4	no	9.686	9.846	EPSD	COSMIC;GDSC;CCLE	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P13631	RARG	P27361	MAPK3	S427	G430S	430	Missense	distal	3	no	10.051	10.067	EPSD	COSMIC;GDSC;CCLE	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P13631	RARG	P27361	MAPK3	S436	G430S	430	Missense	distal	-6	no	10.454	10.516	EPSD	COSMIC;GDSC;CCLE	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P33981	TTK	P27361	MAPK3	S108	N106T	106	Missense	proximal	-2	no	8.562	9.596	EPSD	COSMIC	9.358	Gain
CMGC_MAPK_ERK1_MAPK3_ST	P33981	TTK	P27361	MAPK3	S214	V208A	208	Missense	distal	-6	no	10.029	10.042	EPSD	COSMIC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P33981	TTK	P27361	MAPK3	S436	T441I	441	Missense	distal	5	no	17.730	17.472	EPSD	COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P33981	TTK	P27361	MAPK3	S440	T441I	441	Missense	proximal	1	no	9.428	8.798	EPSD	COSMIC	9.358	Loss
CMGC_MAPK_ERK1_MAPK3_ST	P33981	TTK	P27361	MAPK3	T453	S455N	455	Missense	proximal	2	no	10.836	10.819	EPSD	COSMIC;GDSC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P33981	TTK	P27361	MAPK3	T453	T458A	458	Missense	distal	5	no	10.836	10.717	EPSD	COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P33981	TTK	P27361	MAPK3	T453	K452N	452	Missense	proximal	-1	no	10.836	10.842	EPSD	COSMIC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P33981	TTK	P27361	MAPK3	T453	K452E	452	Missense	proximal	-1	no	10.836	10.867	EPSD	COSMIC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P33981	TTK	P27361	MAPK3	T453	S455R	455	Missense	proximal	2	no	10.836	10.824	EPSD	COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P33981	TTK	P27361	MAPK3	T453	S455I	455	Missense	proximal	2	no	10.836	10.801	EPSD	COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P33981	TTK	P27361	MAPK3	S464	C465F	465	Missense	proximal	1	no	1.232	10.326	EPSD	COSMIC	9.358	Gain
CMGC_MAPK_ERK1_MAPK3_ST	P33981	TTK	P27361	MAPK3	T468	D474N	474	Missense	distal	6	no	15.750	15.698	EPSD	COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P33981	TTK	P27361	MAPK3	T468	C465F	465	Missense	distal	-3	no	15.750	15.787	EPSD	COSMIC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P33981	TTK	P27361	MAPK3	T468	T468A	468	Missense	central	0	yes	15.750	0.000	EPSD	COSMIC	9.358	Loss
CMGC_MAPK_ERK1_MAPK3_ST	P33981	TTK	P27361	MAPK3	T468	M463T	463	Missense	distal	-5	no	15.750	15.853	EPSD	COSMIC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P33981	TTK	P27361	MAPK3	S582	R587Q	587	Missense	distal	5	no	9.807	9.805	EPSD	COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P33981	TTK	P27361	MAPK3	S582	I586V	586	Missense	distal	4	no	9.807	9.925	EPSD	COSMIC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P33981	TTK	P27361	MAPK3	S582	I586T	586	Missense	distal	4	no	9.807	10.035	EPSD	COSMIC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P33981	TTK	P27361	MAPK3	S582	L588F	588	Missense	distal	6	no	9.807	9.450	EPSD	COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P33981	TTK	P27361	MAPK3	S582	H581Q	581	Missense	proximal	-1	no	9.807	9.765	EPSD	COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P33981	TTK	P27361	MAPK3	S821	P822S	822	Missense	proximal	1	no	15.858	6.805	PhosphoSitePlus	COSMIC	9.358	Loss
CMGC_MAPK_ERK1_MAPK3_ST	P33981	TTK	P27361	MAPK3	S821	A828V	828	Missense	distal	7	no	15.858	15.830	PhosphoSitePlus	COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P33981	TTK	P27361	MAPK3	S821	N823H	823	Missense	proximal	2	no	15.858	15.861	PhosphoSitePlus	COSMIC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P33981	TTK	P27361	MAPK3	S844	K848R	848	Missense	distal	4	no	10.791	10.783	EPSD	COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P33981	TTK	P27361	MAPK3	S844	N843I	843	Missense	proximal	-1	no	10.791	10.708	EPSD	COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P33981	TTK	P27361	MAPK3	S847	K848R	848	Missense	proximal	1	no	3.450	11.103	EPSD	COSMIC	9.358	Gain
CMGC_MAPK_ERK1_MAPK3_ST	P33981	TTK	P27361	MAPK3	T849	K856N	856	Missense	distal	7	no	11.635	11.626	EPSD	COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P33981	TTK	P27361	MAPK3	T849	G855R	855	Missense	distal	6	no	11.635	11.626	EPSD	COSMIC;GDSC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P33981	TTK	P27361	MAPK3	T849	G855E	855	Missense	distal	6	no	11.635	11.736	EPSD	COSMIC;CCLE	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P33981	TTK	P27361	MAPK3	T849	K848R	848	Missense	proximal	-1	no	11.635	11.649	EPSD	COSMIC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P33981	TTK	P27361	MAPK3	T849	K853Q	853	Missense	distal	4	no	11.635	11.583	EPSD	COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P33981	TTK	P27361	MAPK3	T849	N843I	843	Missense	distal	-6	no	11.635	11.360	EPSD	COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P33981	TTK	P27361	MAPK3	T849	K852Q	852	Missense	distal	3	no	11.635	11.637	EPSD	COSMIC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q86UR1	NOXA1	P27361	MAPK3	S239	R241I	241	Missense	proximal	2	no	14.287	14.265	EPSD	COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q86UR1	NOXA1	P27361	MAPK3	S239	P240Q	240	Missense	proximal	1	no	14.287	6.343	EPSD	COSMIC	9.358	Loss
CMGC_MAPK_ERK1_MAPK3_ST	Q86UR1	NOXA1	P27361	MAPK3	S239	S234P	234	Missense	distal	-5	no	14.287	14.282	EPSD	COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q86UR1	NOXA1	P27361	MAPK3	S239	H245Y	245	Missense	distal	6	no	14.287	14.128	EPSD	COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q86UR1	NOXA1	P27361	MAPK3	S239	S239P	239	Missense	central	0	yes	14.287	0.000	EPSD	COSMIC	9.358	Loss
CMGC_MAPK_ERK1_MAPK3_ST	Q86UR1	NOXA1	P27361	MAPK3	S282	P286L	286	Missense	distal	4	no	16.898	16.743	PhosphoSitePlus	COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q86UR1	NOXA1	P27361	MAPK3	S409	V404M	404	Missense	distal	-5	no	10.299	10.257	EPSD	COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q86UR1	NOXA1	P27361	MAPK3	S409	P415R	415	Missense	distal	6	no	10.299	10.187	EPSD	COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q86UR1	NOXA1	P27361	MAPK3	S409	S411P	411	Missense	proximal	2	no	10.299	10.297	EPSD	COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	O60331	PIP5K1C	P27361	MAPK3	S355	A352V	352	Missense	distal	-3	no	9.471	9.490	EPSD	COSMIC;GDSC;CCLE	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	O60331	PIP5K1C	P27361	MAPK3	S355	A352T	352	Missense	distal	-3	no	9.471	9.532	EPSD	COSMIC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	O60331	PIP5K1C	P27361	MAPK3	S453	G460S	460	Missense	distal	7	no	13.524	13.384	EPSD	COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	O60331	PIP5K1C	P27361	MAPK3	S453	G460C	460	Missense	distal	7	no	13.524	13.996	EPSD	COSMIC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	O60331	PIP5K1C	P27361	MAPK3	S453	S448F	448	Missense	distal	-5	no	13.524	13.389	EPSD	COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	O60331	PIP5K1C	P27361	MAPK3	S515	T512M	512	Missense	distal	-3	no	11.215	11.118	EPSD	COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	O60331	PIP5K1C	P27361	MAPK3	S515	E517K	517	Missense	proximal	2	no	11.215	11.207	EPSD	COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	O60331	PIP5K1C	P27361	MAPK3	T531	S532P	532	Missense	proximal	1	no	4.408	13.462	EPSD	COSMIC;GDSC;CCLE	9.358	Gain
CMGC_MAPK_ERK1_MAPK3_ST	O60331	PIP5K1C	P27361	MAPK3	S539	R538L	538	Missense	proximal	-1	no	16.757	16.710	EPSD	COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	O60331	PIP5K1C	P27361	MAPK3	S539	S532P	532	Missense	distal	-7	no	16.757	16.794	EPSD	COSMIC;GDSC;CCLE	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	O60331	PIP5K1C	P27361	MAPK3	T553	R552G	552	Missense	proximal	-1	no	10.824	10.800	EPSD	COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	O60331	PIP5K1C	P27361	MAPK3	T553	R552C	552	Missense	proximal	-1	no	10.824	10.639	EPSD	COSMIC;GDSC;CCLE	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	O60331	PIP5K1C	P27361	MAPK3	T553	R552L	552	Missense	proximal	-1	no	10.824	10.777	EPSD	COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	O60331	PIP5K1C	P27361	MAPK3	S650	L652F	652	Missense	proximal	2	no	18.963	18.936	PhosphoSitePlus	COSMIC;CCLE	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	O60331	PIP5K1C	P27361	MAPK3	S650	H653P	653	Missense	distal	3	no	18.963	18.982	PhosphoSitePlus	COSMIC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	O60331	PIP5K1C	P27361	MAPK3	S655	L652F	652	Missense	distal	-3	no	9.580	9.514	EPSD	COSMIC;CCLE	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	O60331	PIP5K1C	P27361	MAPK3	S655	H653P	653	Missense	proximal	-2	no	9.580	10.807	EPSD	COSMIC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P27824	CANX	P27361	MAPK3	S55	K61I	61	Missense	distal	6	no	18.319	17.958	EPSD	COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P27824	CANX	P27361	MAPK3	S55	P52H	52	Missense	distal	-3	no	18.319	18.279	EPSD	COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P27824	CANX	P27361	MAPK3	S55	K57N	57	Missense	proximal	2	no	18.319	18.318	EPSD	COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P27824	CANX	P27361	MAPK3	S564	S564G	564	Missense	central	0	yes	11.048	0.000	EPSD	COSMIC	9.358	Loss
CMGC_MAPK_ERK1_MAPK3_ST	P27824	CANX	P27361	MAPK3	S564	E557K	557	Missense	distal	-7	no	11.048	11.100	EPSD	COSMIC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P27824	CANX	P27361	MAPK3	S583	I579S	579	Missense	distal	-4	no	18.094	18.253	PhosphoSitePlus	COSMIC;CCLE	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P27824	CANX	P27361	MAPK3	S583	P584Q	584	Missense	proximal	1	no	18.094	10.150	PhosphoSitePlus	COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q12931	TRAP1	P27361	MAPK3	S282	F280L	280	Missense	proximal	-2	no	9.034	10.025	EPSD	COSMIC	9.358	Gain
CMGC_MAPK_ERK1_MAPK3_ST	Q12931	TRAP1	P27361	MAPK3	S472	Q479H	479	Missense	distal	7	no	9.483	9.420	EPSD	COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q92908	GATA6	P27361	MAPK3	S44	E51K	51	Missense	distal	7	no	9.510	9.581	EPSD	COSMIC;GDSC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q92908	GATA6	P27361	MAPK3	T62	A57D	57	Missense	distal	-5	no	10.474	10.538	EPSD	COSMIC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q92908	GATA6	P27361	MAPK3	S436	S437P	437	Missense	proximal	1	no	8.256	17.310	EPSD	COSMIC	9.358	Gain
CMGC_MAPK_ERK1_MAPK3_ST	Q92908	GATA6	P27361	MAPK3	T515	S518F	518	Missense	distal	3	no	18.227	18.163	EPSD	COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q92908	GATA6	P27361	MAPK3	S531	T537A	537	Missense	distal	6	no	17.038	16.667	EPSD	COSMIC;GDSC;CCLE	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q92908	GATA6	P27361	MAPK3	S531	S531Y	531	Missense	central	0	yes	17.038	0.000	EPSD	COSMIC	9.358	Loss
CMGC_MAPK_ERK1_MAPK3_ST	Q92908	GATA6	P27361	MAPK3	T534	T537A	537	Missense	distal	3	no	9.798	9.767	EPSD	COSMIC;GDSC;CCLE	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q92908	GATA6	P27361	MAPK3	T534	A541V	541	Missense	distal	7	no	9.798	9.770	EPSD	COSMIC;GDSC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q92908	GATA6	P27361	MAPK3	T534	S531Y	531	Missense	distal	-3	no	9.798	9.735	EPSD	COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q86UC2	RSPH3	P27361	MAPK3	T243	E248K	248	Missense	distal	5	no	16.075	15.947	EPSD	COSMIC;CCLE	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q86UC2	RSPH3	P27361	MAPK3	T243	P246R	246	Missense	distal	3	no	16.075	16.049	EPSD	COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q86UC2	RSPH3	P27361	MAPK3	T286	A292P	292	Missense	distal	6	no	16.241	16.637	PhosphoSitePlus	COSMIC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q86UC2	RSPH3	P27361	MAPK3	T286	D282E	282	Missense	distal	-4	no	16.241	16.252	PhosphoSitePlus	COSMIC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q86UC2	RSPH3	P27361	MAPK3	T286	A279E	279	Missense	distal	-7	no	16.241	16.124	PhosphoSitePlus	COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q86UC2	RSPH3	P27361	MAPK3	S553	E556K	556	Missense	distal	3	no	11.104	11.094	EPSD	COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q9UQC2	GAB2	P27361	MAPK3	S140	P138R	138	Missense	proximal	-2	no	9.973	8.573	EPSD	COSMIC	9.358	Loss
CMGC_MAPK_ERK1_MAPK3_ST	Q9UQC2	GAB2	P27361	MAPK3	S141	P138R	138	Missense	distal	-3	no	18.281	18.235	EPSD	COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q9UQC2	GAB2	P27361	MAPK3	T171	S164F	164	Missense	distal	-7	no	9.953	10.173	EPSD	COSMIC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q9UQC2	GAB2	P27361	MAPK3	T171	P174S	174	Missense	distal	3	no	9.953	9.949	EPSD	COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q9UQC2	GAB2	P27361	MAPK3	T171	P167S	167	Missense	distal	-4	no	9.953	9.981	EPSD	COSMIC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q9UQC2	GAB2	P27361	MAPK3	T265	T259M	259	Missense	distal	-6	no	9.756	9.503	EPSD	COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q9UQC2	GAB2	P27361	MAPK3	T265	P269S	269	Missense	distal	4	no	9.756	9.805	EPSD	COSMIC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q9UQC2	GAB2	P27361	MAPK3	T265	N258S	258	Missense	distal	-7	no	9.756	9.689	EPSD	COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q9UQC2	GAB2	P27361	MAPK3	T294	D288N	288	Missense	distal	-6	no	9.384	9.322	EPSD	COSMIC	9.358	Loss
CMGC_MAPK_ERK1_MAPK3_ST	Q9UQC2	GAB2	P27361	MAPK3	T294	T297M	297	Missense	distal	3	no	9.384	9.335	EPSD	COSMIC;GDSC	9.358	Loss
CMGC_MAPK_ERK1_MAPK3_ST	Q9UQC2	GAB2	P27361	MAPK3	T294	T287I	287	Missense	distal	-7	no	9.384	9.499	EPSD	COSMIC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q9UQC2	GAB2	P27361	MAPK3	T294	T301N	301	Missense	distal	7	no	9.384	9.431	EPSD	COSMIC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q9UQC2	GAB2	P27361	MAPK3	T319	M314I	314	Missense	distal	-5	no	16.047	16.071	EPSD	COSMIC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q9UQC2	GAB2	P27361	MAPK3	T319	P317L	317	Missense	proximal	-2	no	16.047	14.662	EPSD	COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q9UQC2	GAB2	P27361	MAPK3	T319	A318T	318	Missense	proximal	-1	no	16.047	16.150	EPSD	COSMIC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q9UQC2	GAB2	P27361	MAPK3	S368	Q370R	370	Missense	proximal	2	no	16.275	16.284	EPSD	COSMIC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q9UQC2	GAB2	P27361	MAPK3	S368	G367D	367	Missense	proximal	-1	no	16.275	16.294	EPSD	COSMIC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q9UQC2	GAB2	P27361	MAPK3	T391	L392P	392	Missense	proximal	1	no	7.081	16.119	EPSD	COSMIC	9.358	Gain
CMGC_MAPK_ERK1_MAPK3_ST	Q9UQC2	GAB2	P27361	MAPK3	S480	D487N	487	Missense	distal	7	no	17.922	17.981	EPSD	COSMIC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q9UQC2	GAB2	P27361	MAPK3	S480	H484N	484	Missense	distal	4	no	17.922	17.916	EPSD	COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q9UQC2	GAB2	P27361	MAPK3	S543	P544H	544	Missense	proximal	1	no	15.174	7.418	EPSD	COSMIC	9.358	Loss
CMGC_MAPK_ERK1_MAPK3_ST	Q9UQC2	GAB2	P27361	MAPK3	S543	D537G	537	Missense	distal	-6	no	15.174	15.172	EPSD	COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q9UQC2	GAB2	P27361	MAPK3	S543	E538K	538	Missense	distal	-5	no	15.174	15.162	EPSD	COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q9UQC2	GAB2	P27361	MAPK3	S623	Q620P	620	Missense	distal	-3	no	18.019	18.073	PhosphoSitePlus	COSMIC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q9UQC2	GAB2	P27361	MAPK3	S625	S631C	631	Missense	distal	6	no	16.490	15.623	EPSD	COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q9UQC2	GAB2	P27361	MAPK3	S625	Q620P	620	Missense	distal	-5	no	16.490	16.538	EPSD	COSMIC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q9UQC2	GAB2	P27361	MAPK3	S634	V635I	635	Missense	proximal	1	no	9.648	9.563	EPSD	COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q9UQC2	GAB2	P27361	MAPK3	S634	S631C	631	Missense	distal	-3	no	9.648	9.470	EPSD	COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P10828	THRB	P27361	MAPK3	S55	L58F	58	Missense	distal	3	no	16.674	16.641	EPSD	COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P10828	THRB	P27361	MAPK3	S55	I59L	59	Missense	distal	4	no	16.674	16.811	EPSD	COSMIC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P10828	THRB	P27361	MAPK3	S55	Q53R	53	Missense	proximal	-2	no	16.674	17.038	EPSD	COSMIC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P10828	THRB	P27361	MAPK3	S142	S142F	142	Missense	central	0	yes	10.118	0.000	PhosphoSitePlus	COSMIC	9.358	Loss
CMGC_MAPK_ERK1_MAPK3_ST	P10301	RRAS	P27361	MAPK3	S201	R207K	207	Missense	distal	6	no	20.640	20.674	PhosphoSitePlus	COSMIC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P10301	RRAS	P27361	MAPK3	S201	A205V	205	Missense	distal	4	no	20.640	20.748	PhosphoSitePlus	COSMIC;GDSC;CCLE	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P10301	RRAS	P27361	MAPK3	S204	R207K	207	Missense	distal	3	no	11.768	11.767	EPSD	COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P10301	RRAS	P27361	MAPK3	S204	A205V	205	Missense	proximal	1	no	11.768	11.585	EPSD	COSMIC;GDSC;CCLE	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q92797	SYMPK	P27361	MAPK3	S16	V9I	9	Missense	distal	-7	no	10.950	10.992	EPSD	COSMIC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q92797	SYMPK	P27361	MAPK3	S16	R11H	11	Missense	distal	-5	no	10.950	10.960	EPSD	COSMIC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q92797	SYMPK	P27361	MAPK3	S16	E22K	22	Missense	distal	6	no	10.950	10.874	EPSD	COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q92797	SYMPK	P27361	MAPK3	S16	R12W	12	Missense	distal	-4	no	10.950	10.743	EPSD	COSMIC;CCLE	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q92797	SYMPK	P27361	MAPK3	S16	R12Q	12	Missense	distal	-4	no	10.950	10.960	EPSD	COSMIC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q92797	SYMPK	P27361	MAPK3	S195	T193A	193	Missense	proximal	-2	no	16.815	15.450	EPSD	COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q92797	SYMPK	P27361	MAPK3	S938	P939T	939	Missense	proximal	1	no	16.166	7.288	EPSD	COSMIC	9.358	Loss
CMGC_MAPK_ERK1_MAPK3_ST	Q92797	SYMPK	P27361	MAPK3	S938	P939S	939	Missense	proximal	1	no	16.166	7.112	EPSD	COSMIC	9.358	Loss
CMGC_MAPK_ERK1_MAPK3_ST	Q92797	SYMPK	P27361	MAPK3	S1081	P1084F	1084	Missense	distal	3	no	9.423	9.354	EPSD	COSMIC	9.358	Loss
CMGC_MAPK_ERK1_MAPK3_ST	Q92797	SYMPK	P27361	MAPK3	T1083	P1084F	1084	Missense	proximal	1	no	16.399	10.185	EPSD	COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q92797	SYMPK	P27361	MAPK3	S1169	G1165R	1165	Missense	distal	-4	no	10.433	10.395	EPSD	COSMIC;CCLE	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q92797	SYMPK	P27361	MAPK3	S1171	G1165R	1165	Missense	distal	-6	no	17.186	17.088	EPSD	COSMIC;CCLE	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q92797	SYMPK	P27361	MAPK3	S1243	Q1245H	1245	Missense	proximal	2	no	17.169	17.176	EPSD	COSMIC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q92797	SYMPK	P27361	MAPK3	T1246	Q1245H	1245	Missense	proximal	-1	no	9.525	9.566	EPSD	COSMIC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q9NRF2	SH2B1	P27361	MAPK3	S25	E31D	31	Missense	distal	6	no	13.831	13.786	EPSD	COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q9NRF2	SH2B1	P27361	MAPK3	S88	A81T	81	Missense	distal	-7	no	17.328	17.254	EPSD	COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q9NRF2	SH2B1	P27361	MAPK3	S88	S84N	84	Missense	distal	-4	no	17.328	17.267	EPSD	COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q9NRF2	SH2B1	P27361	MAPK3	S96	P103T	103	Missense	distal	7	no	16.625	16.666	PhosphoSitePlus	COSMIC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q9NRF2	SH2B1	P27361	MAPK3	S102	L108V	108	Missense	distal	6	no	16.228	16.146	EPSD	COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q9NRF2	SH2B1	P27361	MAPK3	S102	P103T	103	Missense	proximal	1	no	16.228	7.351	EPSD	COSMIC	9.358	Loss
CMGC_MAPK_ERK1_MAPK3_ST	Q9NRF2	SH2B1	P27361	MAPK3	S102	E109Q	109	Missense	distal	7	no	16.228	16.323	EPSD	COSMIC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q9NRF2	SH2B1	P27361	MAPK3	S138	S139F	139	Missense	proximal	1	no	8.216	11.056	EPSD	COSMIC	9.358	Gain
CMGC_MAPK_ERK1_MAPK3_ST	Q9NRF2	SH2B1	P27361	MAPK3	S144	S139F	139	Missense	distal	-5	no	9.509	9.375	EPSD	COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q9NRF2	SH2B1	P27361	MAPK3	S144	K146R	146	Missense	proximal	2	no	9.509	9.513	EPSD	COSMIC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q9NRF2	SH2B1	P27361	MAPK3	S144	K151N	151	Missense	distal	7	no	9.509	9.500	EPSD	COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q9NRF2	SH2B1	P27361	MAPK3	S219	D216G	216	Missense	distal	-3	no	15.125	15.115	EPSD	COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q9NRF2	SH2B1	P27361	MAPK3	S219	P220S	220	Missense	proximal	1	no	15.125	6.072	EPSD	COSMIC	9.358	Loss
CMGC_MAPK_ERK1_MAPK3_ST	Q9NRF2	SH2B1	P27361	MAPK3	S376	C380R	380	Missense	distal	4	no	11.443	11.800	EPSD	COSMIC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q9NRF2	SH2B1	P27361	MAPK3	S376	P377L	377	Missense	proximal	1	no	11.443	2.405	EPSD	COSMIC	9.358	Loss
CMGC_MAPK_ERK1_MAPK3_ST	Q9NRF2	SH2B1	P27361	MAPK3	S384	C380R	380	Missense	distal	-4	no	13.920	14.081	EPSD	COSMIC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q9NRF2	SH2B1	P27361	MAPK3	S384	P377L	377	Missense	distal	-7	no	13.920	14.027	EPSD	COSMIC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P53355	DAPK1	P27361	MAPK3	T180	P186L	186	Missense	distal	6	no	11.848	11.621	EPSD	COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P53355	DAPK1	P27361	MAPK3	T612	R611Q	611	Missense	proximal	-1	no	13.278	13.239	EPSD	COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P53355	DAPK1	P27361	MAPK3	T612	L616F	616	Missense	distal	4	no	13.278	13.067	EPSD	COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P53355	DAPK1	P27361	MAPK3	S734	R730K	730	Missense	distal	-4	no	20.876	20.869	PhosphoSitePlus	COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P53355	DAPK1	P27361	MAPK3	S734	P733L	733	Missense	proximal	-1	no	20.876	20.782	PhosphoSitePlus	COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P53355	DAPK1	P27361	MAPK3	T1053	K1047T	1047	Missense	distal	-6	no	14.530	14.520	EPSD	COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P53355	DAPK1	P27361	MAPK3	T1053	H1059R	1059	Missense	distal	6	no	14.530	14.511	EPSD	COSMIC;GDSC;CCLE	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P53355	DAPK1	P27361	MAPK3	T1053	A1056V	1056	Missense	distal	3	no	14.530	14.536	EPSD	COSMIC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P53355	DAPK1	P27361	MAPK3	S1115	A1117S	1117	Missense	proximal	2	no	10.334	10.373	EPSD	COSMIC;GDSC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P53355	DAPK1	P27361	MAPK3	S1115	E1119D	1119	Missense	distal	4	no	10.334	10.314	EPSD	COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P53355	DAPK1	P27361	MAPK3	S1425	T1419S	1419	Missense	distal	-6	no	9.567	9.735	EPSD	COSMIC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q16254	E2F4	P27361	MAPK3	S218	P212S	212	Missense	distal	-6	no	16.771	16.855	EPSD	COSMIC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q16254	E2F4	P27361	MAPK3	S218	P219S	219	Missense	proximal	1	no	16.771	7.717	EPSD	COSMIC	9.358	Loss
CMGC_MAPK_ERK1_MAPK3_ST	Q16254	E2F4	P27361	MAPK3	S218	E213K	213	Missense	distal	-5	no	16.771	16.759	EPSD	COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q16254	E2F4	P27361	MAPK3	T224	P219S	219	Missense	distal	-5	no	16.649	16.654	EPSD	COSMIC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q16254	E2F4	P27361	MAPK3	T224	P229L	229	Missense	distal	5	no	16.649	16.421	EPSD	COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q16254	E2F4	P27361	MAPK3	S244	R241C	241	Missense	distal	-3	no	16.884	16.744	EPSD;PhosphoSitePlus	COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q16254	E2F4	P27361	MAPK3	S244	P242L	242	Missense	proximal	-2	no	16.884	15.500	EPSD;PhosphoSitePlus	COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q16254	E2F4	P27361	MAPK3	T248	R241C	241	Missense	distal	-7	no	12.642	12.829	EPSD	COSMIC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q16254	E2F4	P27361	MAPK3	T248	S255N	255	Missense	distal	7	no	12.642	12.808	EPSD	COSMIC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q16254	E2F4	P27361	MAPK3	T248	P242L	242	Missense	distal	-6	no	12.642	12.395	EPSD	COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q16254	E2F4	P27361	MAPK3	S384	R382C	382	Missense	proximal	-2	no	17.924	15.808	PhosphoSitePlus;EPSD	COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q16254	E2F4	P27361	MAPK3	S384	D391H	391	Missense	distal	7	no	17.924	17.954	PhosphoSitePlus;EPSD	COSMIC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q16254	E2F4	P27361	MAPK3	S384	D391N	391	Missense	distal	7	no	17.924	17.983	PhosphoSitePlus;EPSD	COSMIC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q8NET8	TRPV3	P27361	MAPK3	T264	A270P	270	Missense	distal	6	no	13.493	13.889	PhosphoSitePlus	COSMIC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q8NET8	TRPV3	P27361	MAPK3	T264	E257K	257	Missense	distal	-7	no	13.493	13.545	PhosphoSitePlus	COSMIC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q8NET8	TRPV3	P27361	MAPK3	T264	A269E	269	Missense	distal	5	no	13.493	13.725	PhosphoSitePlus	COSMIC;GDSC;CCLE	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q8NET8	TRPV3	P27361	MAPK3	T264	F259V	259	Missense	distal	-5	no	13.493	13.552	PhosphoSitePlus	COSMIC;CCLE	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q8NET8	TRPV3	P27361	MAPK3	T264	L268P	268	Missense	distal	4	no	13.493	13.648	PhosphoSitePlus	COSMIC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P41182	BCL6	P27361	MAPK3	S3	A5T	5	Missense	proximal	2	no	12.756	12.784	EPSD	COSMIC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P41182	BCL6	P27361	MAPK3	S3	S3L	3	Missense	central	0	yes	12.756	0.000	EPSD	COSMIC	9.358	Loss
CMGC_MAPK_ERK1_MAPK3_ST	P41182	BCL6	P27361	MAPK3	S3	Q10R	10	Missense	distal	7	no	12.756	12.727	EPSD	COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P41182	BCL6	P27361	MAPK3	S3	P4L	4	Missense	proximal	1	no	12.756	3.718	EPSD	COSMIC	9.358	Loss
CMGC_MAPK_ERK1_MAPK3_ST	P41182	BCL6	P27361	MAPK3	S250	S250Y	250	Missense	central	0	yes	16.503	0.000	EPSD	COSMIC	9.358	Loss
CMGC_MAPK_ERK1_MAPK3_ST	P41182	BCL6	P27361	MAPK3	S250	P245L	245	Missense	distal	-5	no	16.503	16.448	EPSD	COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P41182	BCL6	P27361	MAPK3	S250	N252H	252	Missense	proximal	2	no	16.503	16.505	EPSD	COSMIC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P41182	BCL6	P27361	MAPK3	S250	C254Y	254	Missense	distal	4	no	16.503	16.790	EPSD	COSMIC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P41182	BCL6	P27361	MAPK3	S260	E263K	263	Missense	distal	3	no	15.759	15.749	EPSD	COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P41182	BCL6	P27361	MAPK3	S260	P261S	261	Missense	proximal	1	no	15.759	6.706	EPSD	COSMIC	9.358	Loss
CMGC_MAPK_ERK1_MAPK3_ST	P41182	BCL6	P27361	MAPK3	S260	E267K	267	Missense	distal	7	no	15.759	15.830	EPSD	COSMIC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P41182	BCL6	P27361	MAPK3	S260	S260L	260	Missense	central	0	yes	15.759	0.000	EPSD	COSMIC	9.358	Loss
CMGC_MAPK_ERK1_MAPK3_ST	P41182	BCL6	P27361	MAPK3	S260	C254Y	254	Missense	distal	-6	no	15.759	16.065	EPSD	COSMIC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P41182	BCL6	P27361	MAPK3	S260	P261L	261	Missense	proximal	1	no	15.759	6.721	EPSD	COSMIC	9.358	Loss
CMGC_MAPK_ERK1_MAPK3_ST	P41182	BCL6	P27361	MAPK3	S330	G327C	327	Missense	distal	-3	no	15.960	15.815	EPSD	COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P41182	BCL6	P27361	MAPK3	S330	V329A	329	Missense	proximal	-1	no	15.960	15.910	EPSD	COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P41182	BCL6	P27361	MAPK3	S330	S330C	330	Missense	central	0	yes	15.960	0.000	EPSD	COSMIC	9.358	Loss
CMGC_MAPK_ERK1_MAPK3_ST	P41182	BCL6	P27361	MAPK3	S330	G327S	327	Missense	distal	-3	no	15.960	15.992	EPSD	COSMIC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P41182	BCL6	P27361	MAPK3	S333	G327C	327	Missense	distal	-6	no	17.639	17.142	PhosphoSitePlus;EPSD	COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P41182	BCL6	P27361	MAPK3	S333	V329A	329	Missense	distal	-4	no	17.639	17.660	PhosphoSitePlus;EPSD	COSMIC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P41182	BCL6	P27361	MAPK3	S333	S330C	330	Missense	distal	-3	no	17.639	17.462	PhosphoSitePlus;EPSD	COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P41182	BCL6	P27361	MAPK3	S333	G327S	327	Missense	distal	-6	no	17.639	17.702	PhosphoSitePlus;EPSD	COSMIC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P41182	BCL6	P27361	MAPK3	S333	D338G	338	Missense	distal	5	no	17.639	17.617	PhosphoSitePlus;EPSD	COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P41182	BCL6	P27361	MAPK3	S343	P344A	344	Missense	proximal	1	no	20.314	11.074	EPSD;PhosphoSitePlus	COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P41182	BCL6	P27361	MAPK3	S343	S349G	349	Missense	distal	6	no	20.314	20.082	EPSD;PhosphoSitePlus	COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P41182	BCL6	P27361	MAPK3	S343	D338G	338	Missense	distal	-5	no	20.314	20.305	EPSD;PhosphoSitePlus	COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P41182	BCL6	P27361	MAPK3	S361	S361F	361	Missense	central	0	yes	16.217	0.000	EPSD	COSMIC	9.358	Loss
CMGC_MAPK_ERK1_MAPK3_ST	P41182	BCL6	P27361	MAPK3	S361	L356F	356	Missense	distal	-5	no	16.217	16.143	EPSD	COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P41182	BCL6	P27361	MAPK3	S361	C354Y	354	Missense	distal	-7	no	16.217	16.066	EPSD	COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P41182	BCL6	P27361	MAPK3	S361	P367H	367	Missense	distal	6	no	16.217	16.124	EPSD	COSMIC;GDSC;CCLE	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P41182	BCL6	P27361	MAPK3	S361	P363S	363	Missense	proximal	2	no	16.217	16.219	EPSD	COSMIC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P41182	BCL6	P27361	MAPK3	S361	P363L	363	Missense	proximal	2	no	16.217	16.196	EPSD	COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P41182	BCL6	P27361	MAPK3	S361	S359F	359	Missense	proximal	-2	no	16.217	14.917	EPSD	COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P41182	BCL6	P27361	MAPK3	S361	P362S	362	Missense	proximal	1	no	16.217	7.164	EPSD	COSMIC	9.358	Loss
CMGC_MAPK_ERK1_MAPK3_ST	P41182	BCL6	P27361	MAPK3	S361	Q357H	357	Missense	distal	-4	no	16.217	16.221	EPSD	COSMIC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P41182	BCL6	P27361	MAPK3	S361	A364S	364	Missense	distal	3	no	16.217	16.261	EPSD	COSMIC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P41182	BCL6	P27361	MAPK3	S366	S361F	361	Missense	distal	-5	no	15.222	15.088	EPSD	COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P41182	BCL6	P27361	MAPK3	S366	P367H	367	Missense	proximal	1	no	15.222	7.467	EPSD	COSMIC;GDSC;CCLE	9.358	Loss
CMGC_MAPK_ERK1_MAPK3_ST	P41182	BCL6	P27361	MAPK3	S366	P363S	363	Missense	distal	-3	no	15.222	15.214	EPSD	COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P41182	BCL6	P27361	MAPK3	S366	P363L	363	Missense	distal	-3	no	15.222	15.138	EPSD	COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P41182	BCL6	P27361	MAPK3	S366	D369Y	369	Missense	distal	3	no	15.222	15.203	EPSD	COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P41182	BCL6	P27361	MAPK3	S366	S359F	359	Missense	distal	-7	no	15.222	15.442	EPSD	COSMIC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P41182	BCL6	P27361	MAPK3	S366	P362S	362	Missense	distal	-4	no	15.222	15.250	EPSD	COSMIC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P41182	BCL6	P27361	MAPK3	S366	A364S	364	Missense	proximal	-2	no	15.222	16.497	EPSD	COSMIC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P41182	BCL6	P27361	MAPK3	S404	A410T	410	Missense	distal	6	no	15.477	15.848	EPSD	COSMIC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P41182	BCL6	P27361	MAPK3	S404	R402C	402	Missense	proximal	-2	no	15.477	13.362	EPSD	COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P41182	BCL6	P27361	MAPK3	S427	S434N	434	Missense	distal	7	no	16.223	16.389	EPSD	COSMIC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P41182	BCL6	P27361	MAPK3	S457	T455M	455	Missense	proximal	-2	no	16.788	15.019	EPSD	COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P41182	BCL6	P27361	MAPK3	S457	P458S	458	Missense	proximal	1	no	16.788	7.734	EPSD	COSMIC;GDSC;CCLE	9.358	Loss
CMGC_MAPK_ERK1_MAPK3_ST	P41182	BCL6	P27361	MAPK3	S457	V450I	450	Missense	distal	-7	no	16.788	16.830	EPSD	COSMIC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P41182	BCL6	P27361	MAPK3	S457	G456V	456	Missense	proximal	-1	no	16.788	16.770	EPSD	COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P41182	BCL6	P27361	MAPK3	S457	M454V	454	Missense	distal	-3	no	16.788	16.843	EPSD	COSMIC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P41182	BCL6	P27361	MAPK3	S457	P458L	458	Missense	proximal	1	no	16.788	7.750	EPSD	COSMIC	9.358	Loss
CMGC_MAPK_ERK1_MAPK3_ST	P41182	BCL6	P27361	MAPK3	S460	T455M	455	Missense	distal	-5	no	9.365	9.263	EPSD	COSMIC	9.358	Loss
CMGC_MAPK_ERK1_MAPK3_ST	P41182	BCL6	P27361	MAPK3	S460	P458S	458	Missense	proximal	-2	no	9.365	8.289	EPSD	COSMIC;GDSC;CCLE	9.358	Loss
CMGC_MAPK_ERK1_MAPK3_ST	P41182	BCL6	P27361	MAPK3	S460	G456V	456	Missense	distal	-4	no	9.365	9.252	EPSD	COSMIC	9.358	Loss
CMGC_MAPK_ERK1_MAPK3_ST	P41182	BCL6	P27361	MAPK3	S460	M454V	454	Missense	distal	-6	no	9.365	9.457	EPSD	COSMIC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P41182	BCL6	P27361	MAPK3	S460	P458L	458	Missense	proximal	-2	no	9.365	7.981	EPSD	COSMIC	9.358	Loss
CMGC_MAPK_ERK1_MAPK3_ST	P41182	BCL6	P27361	MAPK3	S466	P472L	472	Missense	distal	6	no	16.090	15.863	EPSD	COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q13164	MAPK7	P27361	MAPK3	S210	R205P	205	Missense	distal	-5	no	12.253	12.294	EPSD	COSMIC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q13164	MAPK7	P27361	MAPK3	S210	R205C	205	Missense	distal	-5	no	12.253	12.137	EPSD	COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q13164	MAPK7	P27361	MAPK3	T280	P281S	281	Missense	proximal	1	no	15.650	6.596	EPSD	COSMIC	9.358	Loss
CMGC_MAPK_ERK1_MAPK3_ST	Q13164	MAPK7	P27361	MAPK3	S282	V289L	289	Missense	distal	7	no	16.909	16.860	EPSD	COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q13164	MAPK7	P27361	MAPK3	S282	A288V	288	Missense	distal	6	no	16.909	16.996	EPSD	COSMIC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q13164	MAPK7	P27361	MAPK3	S282	P281S	281	Missense	proximal	-1	no	16.909	16.903	EPSD	COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q13164	MAPK7	P27361	MAPK3	S421	C414Y	414	Missense	distal	-7	no	15.099	14.947	EPSD	COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q13164	MAPK7	P27361	MAPK3	S433	M431I	431	Missense	proximal	-2	no	14.748	15.664	EPSD	COSMIC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q13164	MAPK7	P27361	MAPK3	S433	P438L	438	Missense	distal	5	no	14.748	14.520	EPSD	COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q13164	MAPK7	P27361	MAPK3	T553	G550D	550	Missense	distal	-3	no	9.750	9.760	EPSD	COSMIC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q13164	MAPK7	P27361	MAPK3	T553	G558R	558	Missense	distal	5	no	9.750	9.671	EPSD	COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q13164	MAPK7	P27361	MAPK3	T553	A557V	557	Missense	distal	4	no	9.750	9.858	EPSD	COSMIC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q13164	MAPK7	P27361	MAPK3	T553	G558V	558	Missense	distal	5	no	9.750	9.549	EPSD	COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q13164	MAPK7	P27361	MAPK3	T594	A592V	592	Missense	proximal	-2	no	13.741	14.438	EPSD	COSMIC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q13164	MAPK7	P27361	MAPK3	T594	V600L	600	Missense	distal	6	no	13.741	13.823	EPSD	COSMIC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q13164	MAPK7	P27361	MAPK3	T594	P591L	591	Missense	distal	-3	no	13.741	13.657	EPSD	COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q13164	MAPK7	P27361	MAPK3	T594	T594M	594	Missense	central	0	yes	13.741	0.000	EPSD	COSMIC	9.358	Loss
CMGC_MAPK_ERK1_MAPK3_ST	Q13164	MAPK7	P27361	MAPK3	T594	T594I	594	Missense	central	0	yes	13.741	0.000	EPSD	COSMIC	9.358	Loss
CMGC_MAPK_ERK1_MAPK3_ST	Q13164	MAPK7	P27361	MAPK3	T594	P589H	589	Missense	distal	-5	no	13.741	13.710	EPSD	COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q13164	MAPK7	P27361	MAPK3	S720	E723K	723	Missense	distal	3	no	9.594	9.583	EPSD	COSMIC;GDSC;CCLE	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q13164	MAPK7	P27361	MAPK3	S720	S718F	718	Missense	proximal	-2	no	9.594	8.294	EPSD	COSMIC;GDSC;CCLE	9.358	Loss
CMGC_MAPK_ERK1_MAPK3_ST	Q13164	MAPK7	P27361	MAPK3	T733	P728H	728	Missense	distal	-5	no	14.651	14.620	PhosphoSitePlus	COSMIC;GDSC;CCLE	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q13164	MAPK7	P27361	MAPK3	T733	T733I	733	Missense	central	0	yes	14.651	0.000	PhosphoSitePlus	COSMIC	9.358	Loss
CMGC_MAPK_ERK1_MAPK3_ST	Q13164	MAPK7	P27361	MAPK3	S754	N752H	752	Missense	proximal	-2	no	9.140	9.933	EPSD	COSMIC	9.358	Gain
CMGC_MAPK_ERK1_MAPK3_ST	Q13164	MAPK7	P27361	MAPK3	S803	L806R	806	Missense	distal	3	no	17.284	17.294	EPSD	COSMIC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q13164	MAPK7	P27361	MAPK3	S803	S803F	803	Missense	central	0	yes	17.284	0.000	EPSD	COSMIC	9.358	Loss
CMGC_MAPK_ERK1_MAPK3_ST	Q13164	MAPK7	P27361	MAPK3	S803	M805V	805	Missense	proximal	2	no	17.284	17.302	EPSD	COSMIC;GDSC;CCLE	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q13164	MAPK7	P27361	MAPK3	S803	P804S	804	Missense	proximal	1	no	17.284	8.230	EPSD	COSMIC	9.358	Loss
CMGC_MAPK_ERK1_MAPK3_ST	Q13164	MAPK7	P27361	MAPK3	S803	D809N	809	Missense	distal	6	no	17.284	17.231	EPSD	COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q01844	EWSR1	P27361	MAPK3	T79	T81S	81	Missense	proximal	2	no	13.962	13.974	PhosphoSitePlus	COSMIC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q01844	EWSR1	P27361	MAPK3	T79	T75A	75	Missense	distal	-4	no	13.962	13.889	PhosphoSitePlus	COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q01844	EWSR1	P27361	MAPK3	T79	P83H	83	Missense	distal	4	no	13.962	13.871	PhosphoSitePlus	COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q01844	EWSR1	P27361	MAPK3	T79	T78I	78	Missense	proximal	-1	no	13.962	13.861	PhosphoSitePlus	COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q01844	EWSR1	P27361	MAPK3	S416	P421S	421	Missense	distal	5	no	10.319	10.362	EPSD	COSMIC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q01844	EWSR1	P27361	MAPK3	S416	D412N	412	Missense	distal	-4	no	10.319	10.293	EPSD	COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q01844	EWSR1	P27361	MAPK3	S416	T414A	414	Missense	proximal	-2	no	10.319	8.954	EPSD	COSMIC	9.358	Loss
CMGC_MAPK_ERK1_MAPK3_ST	Q9H9Z2	LIN28A	P27361	MAPK3	T189	E193K	193	Missense	distal	4	no	12.129	12.090	EPSD	COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q9H9Z2	LIN28A	P27361	MAPK3	S200	P205Q	205	Missense	distal	5	no	18.673	18.571	PhosphoSitePlus	COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q9H9Z2	LIN28A	P27361	MAPK3	S200	P201S	201	Missense	proximal	1	no	18.673	9.620	PhosphoSitePlus	COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q9H9Z2	LIN28A	P27361	MAPK3	S200	P205L	205	Missense	distal	5	no	18.673	18.445	PhosphoSitePlus	COSMIC;GDSC;CCLE	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q9H9Z2	LIN28A	P27361	MAPK3	S200	L204F	204	Missense	distal	4	no	18.673	18.462	PhosphoSitePlus	COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q9H9Z2	LIN28A	P27361	MAPK3	S200	E193K	193	Missense	distal	-7	no	18.673	18.724	PhosphoSitePlus	COSMIC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q9H9Z2	LIN28A	P27361	MAPK3	S200	E206K	206	Missense	distal	6	no	18.673	18.597	PhosphoSitePlus	COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q9H9Z2	LIN28A	P27361	MAPK3	T202	P205Q	205	Missense	distal	3	no	10.015	9.988	EPSD	COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q9H9Z2	LIN28A	P27361	MAPK3	T202	P201S	201	Missense	proximal	-1	no	10.015	10.009	EPSD	COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q9H9Z2	LIN28A	P27361	MAPK3	T202	Q208H	208	Missense	distal	6	no	10.015	10.103	EPSD	COSMIC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q9H9Z2	LIN28A	P27361	MAPK3	T202	P205L	205	Missense	distal	3	no	10.015	9.978	EPSD	COSMIC;GDSC;CCLE	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q9H9Z2	LIN28A	P27361	MAPK3	T202	L204F	204	Missense	proximal	2	no	10.015	9.988	EPSD	COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q9H9Z2	LIN28A	P27361	MAPK3	T202	E206K	206	Missense	distal	4	no	10.015	9.976	EPSD	COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q12772	SREBF2	P27361	MAPK3	S79	S73L	73	Missense	distal	-6	no	9.393	9.062	EPSD	COSMIC	9.358	Loss
CMGC_MAPK_ERK1_MAPK3_ST	Q12772	SREBF2	P27361	MAPK3	S79	S79N	79	Missense	central	0	yes	9.393	0.000	EPSD	COSMIC	9.358	Loss
CMGC_MAPK_ERK1_MAPK3_ST	Q12772	SREBF2	P27361	MAPK3	S79	G76D	76	Missense	distal	-3	no	9.393	9.403	EPSD	COSMIC;CCLE	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q12772	SREBF2	P27361	MAPK3	S79	A83D	83	Missense	distal	4	no	9.393	9.605	EPSD	COSMIC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q12772	SREBF2	P27361	MAPK3	S79	P86L	86	Missense	distal	7	no	9.393	9.586	EPSD	COSMIC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q12772	SREBF2	P27361	MAPK3	S101	S101F	101	Missense	central	0	yes	16.091	0.000	EPSD	COSMIC	9.358	Loss
CMGC_MAPK_ERK1_MAPK3_ST	Q12772	SREBF2	P27361	MAPK3	S101	S99F	99	Missense	proximal	-2	no	16.091	14.791	EPSD	COSMIC;GDSC;CCLE	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q12772	SREBF2	P27361	MAPK3	S106	S101F	101	Missense	distal	-5	no	14.132	13.998	EPSD	COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q12772	SREBF2	P27361	MAPK3	S106	S99F	99	Missense	distal	-7	no	14.132	14.352	EPSD	COSMIC;GDSC;CCLE	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q12772	SREBF2	P27361	MAPK3	S117	P118S	118	Missense	proximal	1	no	16.101	7.047	EPSD	COSMIC	9.358	Loss
CMGC_MAPK_ERK1_MAPK3_ST	Q12772	SREBF2	P27361	MAPK3	T124	P118S	118	Missense	distal	-6	no	16.527	16.612	EPSD	COSMIC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q12772	SREBF2	P27361	MAPK3	T153	P160Q	160	Missense	distal	7	no	13.587	13.708	EPSD	COSMIC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q12772	SREBF2	P27361	MAPK3	T153	V150A	150	Missense	distal	-3	no	13.587	13.567	EPSD	COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q12772	SREBF2	P27361	MAPK3	T153	P160L	160	Missense	distal	7	no	13.587	13.779	EPSD	COSMIC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q12772	SREBF2	P27361	MAPK3	T155	P160Q	160	Missense	distal	5	no	10.450	10.348	EPSD	COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q12772	SREBF2	P27361	MAPK3	T155	V150A	150	Missense	distal	-5	no	10.450	10.427	EPSD	COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q12772	SREBF2	P27361	MAPK3	T155	P160L	160	Missense	distal	5	no	10.450	10.222	EPSD	COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q12772	SREBF2	P27361	MAPK3	S455	L457F	457	Missense	proximal	2	no	19.584	19.557	PhosphoSitePlus;EPSD	COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q12772	SREBF2	P27361	MAPK3	S455	K462N	462	Missense	distal	7	no	19.584	19.574	PhosphoSitePlus;EPSD	COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q12772	SREBF2	P27361	MAPK3	S455	K462E	462	Missense	distal	7	no	19.584	19.513	PhosphoSitePlus;EPSD	COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q12772	SREBF2	P27361	MAPK3	S455	A461T	461	Missense	distal	6	no	19.584	19.954	PhosphoSitePlus;EPSD	COSMIC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q12772	SREBF2	P27361	MAPK3	S469	S469F	469	Missense	central	0	yes	18.967	0.000	EPSD	COSMIC	9.358	Loss
CMGC_MAPK_ERK1_MAPK3_ST	Q12772	SREBF2	P27361	MAPK3	S469	S469A	469	Missense	central	0	yes	18.967	0.000	EPSD	COSMIC	9.358	Loss
CMGC_MAPK_ERK1_MAPK3_ST	Q12772	SREBF2	P27361	MAPK3	S469	S469C	469	Missense	central	0	yes	18.967	0.000	EPSD	COSMIC	9.358	Loss
CMGC_MAPK_ERK1_MAPK3_ST	Q12772	SREBF2	P27361	MAPK3	S469	K462N	462	Missense	distal	-7	no	18.967	18.951	EPSD	COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q12772	SREBF2	P27361	MAPK3	S469	K462E	462	Missense	distal	-7	no	18.967	18.916	EPSD	COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q12772	SREBF2	P27361	MAPK3	S469	P470S	470	Missense	proximal	1	no	18.967	9.913	EPSD	COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q12772	SREBF2	P27361	MAPK3	S914	E910K	910	Missense	distal	-4	no	17.229	17.169	EPSD	COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q12772	SREBF2	P27361	MAPK3	S1094	S1094F	1094	Missense	central	0	yes	9.761	0.000	EPSD	COSMIC	9.358	Loss
CMGC_MAPK_ERK1_MAPK3_ST	Q12772	SREBF2	P27361	MAPK3	S1094	S1098F	1098	Missense	distal	4	no	9.761	9.346	EPSD	COSMIC	9.358	Loss
CMGC_MAPK_ERK1_MAPK3_ST	Q12772	SREBF2	P27361	MAPK3	S1098	S1094F	1094	Missense	distal	-4	no	16.461	16.272	EPSD	COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q12772	SREBF2	P27361	MAPK3	S1098	S1098F	1098	Missense	central	0	yes	16.461	0.000	EPSD	COSMIC	9.358	Loss
CMGC_MAPK_ERK1_MAPK3_ST	Q12772	SREBF2	P27361	MAPK3	S1121	C1122S	1122	Missense	proximal	1	no	4.014	10.269	EPSD	COSMIC	9.358	Gain
CMGC_MAPK_ERK1_MAPK3_ST	P05787	KRT8	P27361	MAPK3	S24	S31A	31	Missense	distal	7	no	11.213	11.559	EPSD	COSMIC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P05787	KRT8	P27361	MAPK3	S24	S31Y	31	Missense	distal	7	no	11.213	11.468	EPSD	COSMIC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P05787	KRT8	P27361	MAPK3	T26	S31A	31	Missense	distal	5	no	9.689	9.434	EPSD	COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P05787	KRT8	P27361	MAPK3	T26	S31Y	31	Missense	distal	5	no	9.689	9.473	EPSD	COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P05787	KRT8	P27361	MAPK3	S31	S31A	31	Missense	central	0	yes	10.269	0.000	EPSD	COSMIC	9.358	Loss
CMGC_MAPK_ERK1_MAPK3_ST	P05787	KRT8	P27361	MAPK3	S31	S36L	36	Missense	distal	5	no	10.269	9.999	EPSD	COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P05787	KRT8	P27361	MAPK3	S31	S31Y	31	Missense	central	0	yes	10.269	0.000	EPSD	COSMIC	9.358	Loss
CMGC_MAPK_ERK1_MAPK3_ST	P05787	KRT8	P27361	MAPK3	S31	S35F	35	Missense	distal	4	no	10.269	9.855	EPSD	COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P05787	KRT8	P27361	MAPK3	S34	S35F	35	Missense	proximal	1	no	7.698	10.538	EPSD	COSMIC	9.358	Gain
CMGC_MAPK_ERK1_MAPK3_ST	P05787	KRT8	P27361	MAPK3	S37	S43F	43	Missense	distal	6	no	11.111	10.397	EPSD	COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P05787	KRT8	P27361	MAPK3	S37	S31A	31	Missense	distal	-6	no	11.111	10.794	EPSD	COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P05787	KRT8	P27361	MAPK3	S37	S36L	36	Missense	proximal	-1	no	11.111	11.022	EPSD	COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P05787	KRT8	P27361	MAPK3	S37	S43I	43	Missense	distal	6	no	11.111	10.541	EPSD	COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P05787	KRT8	P27361	MAPK3	S37	S43R	43	Missense	distal	6	no	11.111	10.869	EPSD	COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P05787	KRT8	P27361	MAPK3	S37	S31Y	31	Missense	distal	-6	no	11.111	10.858	EPSD	COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P05787	KRT8	P27361	MAPK3	S37	S35F	35	Missense	proximal	-2	no	11.111	9.811	EPSD	COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P05787	KRT8	P27361	MAPK3	S74	S71R	71	Missense	distal	-3	no	16.819	16.781	EPSD	COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P05787	KRT8	P27361	MAPK3	S74	S71I	71	Missense	distal	-3	no	16.819	16.708	EPSD	COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P05787	KRT8	P27361	MAPK3	S74	V77G	77	Missense	distal	3	no	16.819	16.841	EPSD	COSMIC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P05787	KRT8	P27361	MAPK3	S432	G434S	434	Missense	proximal	2	no	15.714	15.730	PhosphoSitePlus	COSMIC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P05787	KRT8	P27361	MAPK3	S436	G434S	434	Missense	proximal	-2	no	10.523	11.563	EPSD	COSMIC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P05787	KRT8	P27361	MAPK3	S451	S449F	449	Missense	proximal	-2	no	12.153	10.853	EPSD	COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P05787	KRT8	P27361	MAPK3	S451	S449A	449	Missense	proximal	-2	no	12.153	10.878	EPSD	COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P05787	KRT8	P27361	MAPK3	S451	S458F	458	Missense	distal	7	no	12.153	12.644	EPSD	COSMIC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P05787	KRT8	P27361	MAPK3	S451	S458T	458	Missense	distal	7	no	12.153	12.271	EPSD	COSMIC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P05787	KRT8	P27361	MAPK3	S451	R454G	454	Missense	distal	3	no	12.153	12.160	EPSD	COSMIC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P05787	KRT8	P27361	MAPK3	S451	A447V	447	Missense	distal	-4	no	12.153	12.133	EPSD	COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P05787	KRT8	P27361	MAPK3	S457	R459M	459	Missense	proximal	2	no	9.641	9.610	EPSD	COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P05787	KRT8	P27361	MAPK3	S457	S458F	458	Missense	proximal	1	no	9.641	12.481	EPSD	COSMIC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P05787	KRT8	P27361	MAPK3	S457	S458T	458	Missense	proximal	1	no	9.641	9.817	EPSD	COSMIC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P05787	KRT8	P27361	MAPK3	S457	R454G	454	Missense	distal	-3	no	9.641	9.646	EPSD	COSMIC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P05787	KRT8	P27361	MAPK3	S477	S477F	477	Missense	central	0	yes	11.362	0.000	EPSD	COSMIC	9.358	Loss
CMGC_MAPK_ERK1_MAPK3_ST	P05787	KRT8	P27361	MAPK3	S477	S478C	478	Missense	proximal	1	no	11.362	5.108	EPSD	COSMIC	9.358	Loss
CMGC_MAPK_ERK1_MAPK3_ST	P06401	PGR	P27361	MAPK3	S20	E22K	22	Missense	proximal	2	no	18.590	18.582	EPSD	COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P06401	PGR	P27361	MAPK3	S20	P21S	21	Missense	proximal	1	no	18.590	9.536	EPSD	COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P06401	PGR	P27361	MAPK3	S20	V23I	23	Missense	distal	3	no	18.590	18.576	EPSD	COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P06401	PGR	P27361	MAPK3	S20	A15V	15	Missense	distal	-5	no	18.590	18.613	EPSD	COSMIC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P06401	PGR	P27361	MAPK3	S20	G24V	24	Missense	distal	4	no	18.590	18.527	EPSD	COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P06401	PGR	P27361	MAPK3	S20	P26Q	26	Missense	distal	6	no	18.590	18.408	EPSD	COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P06401	PGR	P27361	MAPK3	S25	P31T	31	Missense	distal	6	no	19.870	19.845	EPSD	COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P06401	PGR	P27361	MAPK3	S25	E22K	22	Missense	distal	-3	no	19.870	19.839	EPSD	COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P06401	PGR	P27361	MAPK3	S25	P21S	21	Missense	distal	-4	no	19.870	19.898	EPSD	COSMIC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P06401	PGR	P27361	MAPK3	S25	V23I	23	Missense	proximal	-2	no	19.870	19.686	EPSD	COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P06401	PGR	P27361	MAPK3	S25	G24V	24	Missense	proximal	-1	no	19.870	19.852	EPSD	COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P06401	PGR	P27361	MAPK3	S25	P26Q	26	Missense	proximal	1	no	19.870	11.927	EPSD	COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P06401	PGR	P27361	MAPK3	S102	G97E	97	Missense	distal	-5	no	16.064	16.073	EPSD	COSMIC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P06401	PGR	P27361	MAPK3	S102	P103L	103	Missense	proximal	1	no	16.064	7.026	EPSD	COSMIC	9.358	Loss
CMGC_MAPK_ERK1_MAPK3_ST	P06401	PGR	P27361	MAPK3	S102	S99N	99	Missense	distal	-3	no	16.064	16.019	EPSD	COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P06401	PGR	P27361	MAPK3	S102	P103H	103	Missense	proximal	1	no	16.064	8.308	EPSD	COSMIC	9.358	Loss
CMGC_MAPK_ERK1_MAPK3_ST	P06401	PGR	P27361	MAPK3	S130	P131S	131	Missense	proximal	1	no	15.019	5.965	EPSD	COSMIC	9.358	Loss
CMGC_MAPK_ERK1_MAPK3_ST	P06401	PGR	P27361	MAPK3	S130	T137I	137	Missense	distal	7	no	15.019	15.299	EPSD	COSMIC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P06401	PGR	P27361	MAPK3	S162	S168F	168	Missense	distal	6	no	16.966	16.252	EPSD	COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P06401	PGR	P27361	MAPK3	S162	R167W	167	Missense	distal	5	no	16.966	16.498	EPSD	COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P06401	PGR	P27361	MAPK3	S162	M165I	165	Missense	distal	3	no	16.966	16.976	EPSD	COSMIC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P06401	PGR	P27361	MAPK3	S190	R187W	187	Missense	distal	-3	no	15.067	14.899	EPSD	COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P06401	PGR	P27361	MAPK3	S190	R187L	187	Missense	distal	-3	no	15.067	15.029	EPSD	COSMIC;CCLE	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P06401	PGR	P27361	MAPK3	S213	A208D	208	Missense	distal	-5	no	15.680	15.744	EPSD	COSMIC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P06401	PGR	P27361	MAPK3	S213	V219F	219	Missense	distal	6	no	15.680	15.404	EPSD	COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P06401	PGR	P27361	MAPK3	S294	V300M	300	Missense	distal	6	no	17.200	16.989	PhosphoSitePlus	COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P06401	PGR	P27361	MAPK3	S294	A287V	287	Missense	distal	-7	no	17.200	17.199	PhosphoSitePlus	COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P06401	PGR	P27361	MAPK3	S294	A290E	290	Missense	distal	-4	no	17.200	17.307	PhosphoSitePlus	COSMIC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P06401	PGR	P27361	MAPK3	S294	P291S	291	Missense	distal	-3	no	17.200	17.191	PhosphoSitePlus	COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P06401	PGR	P27361	MAPK3	S328	A333S	333	Missense	distal	5	no	10.883	11.138	EPSD	COSMIC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P06401	PGR	P27361	MAPK3	S328	D330E	330	Missense	proximal	2	no	10.883	10.886	EPSD	COSMIC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P06401	PGR	P27361	MAPK3	S328	Q322R	322	Missense	distal	-6	no	10.883	10.873	EPSD	COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P06401	PGR	P27361	MAPK3	S328	Q322K	322	Missense	distal	-6	no	10.883	10.875	EPSD	COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P06401	PGR	P27361	MAPK3	S328	Q322H	322	Missense	distal	-6	no	10.883	10.869	EPSD	COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P06401	PGR	P27361	MAPK3	S345	C347G	347	Missense	proximal	2	no	15.926	15.971	EPSD	COSMIC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P06401	PGR	P27361	MAPK3	S345	S344T	344	Missense	proximal	-1	no	15.926	15.896	EPSD	COSMIC;GDSC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P06401	PGR	P27361	MAPK3	S345	S349L	349	Missense	distal	4	no	15.926	15.723	EPSD	COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P06401	PGR	P27361	MAPK3	S345	P352L	352	Missense	distal	7	no	15.926	16.119	EPSD	COSMIC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P06401	PGR	P27361	MAPK3	T351	C347G	347	Missense	distal	-4	no	17.189	17.388	EPSD	COSMIC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P06401	PGR	P27361	MAPK3	T351	S344T	344	Missense	distal	-7	no	17.189	17.265	EPSD	COSMIC;GDSC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P06401	PGR	P27361	MAPK3	T351	S349L	349	Missense	proximal	-2	no	17.189	16.880	EPSD	COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P06401	PGR	P27361	MAPK3	T351	V353A	353	Missense	proximal	2	no	17.189	17.175	EPSD	COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P06401	PGR	P27361	MAPK3	T351	D357N	357	Missense	distal	6	no	17.189	17.136	EPSD	COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P06401	PGR	P27361	MAPK3	T351	P352L	352	Missense	proximal	1	no	17.189	8.151	EPSD	COSMIC	9.358	Loss
CMGC_MAPK_ERK1_MAPK3_ST	P06401	PGR	P27361	MAPK3	S400	R399C	399	Missense	proximal	-1	no	13.499	13.314	EPSD	COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P06401	PGR	P27361	MAPK3	S400	R399S	399	Missense	proximal	-1	no	13.499	13.541	EPSD	COSMIC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P06401	PGR	P27361	MAPK3	S400	R402C	402	Missense	proximal	2	no	13.499	13.450	EPSD	COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P06401	PGR	P27361	MAPK3	S400	P401L	401	Missense	proximal	1	no	13.499	4.461	EPSD	COSMIC	9.358	Loss
CMGC_MAPK_ERK1_MAPK3_ST	P06401	PGR	P27361	MAPK3	S400	R402H	402	Missense	proximal	2	no	13.499	13.496	EPSD	COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P06401	PGR	P27361	MAPK3	S554	P547L	547	Missense	distal	-7	no	17.793	17.900	EPSD	COSMIC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P06401	PGR	P27361	MAPK3	S558	Q564R	564	Missense	distal	6	no	10.925	10.995	EPSD	COSMIC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P06401	PGR	P27361	MAPK3	S676	I681M	681	Missense	distal	5	no	17.015	17.017	EPSD	COSMIC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P06401	PGR	P27361	MAPK3	S676	I681L	681	Missense	distal	5	no	17.015	17.137	EPSD	COSMIC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q15596	NCOA2	P27361	MAPK3	T197	P191L	191	Missense	distal	-6	no	10.003	9.756	EPSD	COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q15596	NCOA2	P27361	MAPK3	T197	N199S	199	Missense	proximal	2	no	10.003	10.020	EPSD	COSMIC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q15596	NCOA2	P27361	MAPK3	S402	S399G	399	Missense	distal	-3	no	16.657	16.625	EPSD	COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q15596	NCOA2	P27361	MAPK3	S402	L395P	395	Missense	distal	-7	no	16.657	16.550	EPSD	COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q15596	NCOA2	P27361	MAPK3	T457	P458T	458	Missense	proximal	1	no	13.288	4.411	EPSD	COSMIC;GDSC;CCLE	9.358	Loss
CMGC_MAPK_ERK1_MAPK3_ST	Q15596	NCOA2	P27361	MAPK3	S469	S473T	473	Missense	distal	4	no	14.720	14.607	EPSD	COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q15596	NCOA2	P27361	MAPK3	S469	M467I	467	Missense	proximal	-2	no	14.720	15.636	EPSD	COSMIC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q15596	NCOA2	P27361	MAPK3	S469	P470S	470	Missense	proximal	1	no	14.720	5.666	EPSD	COSMIC;GDSC;CCLE	9.358	Loss
CMGC_MAPK_ERK1_MAPK3_ST	Q15596	NCOA2	P27361	MAPK3	S474	S473T	473	Missense	proximal	-1	no	16.202	16.171	EPSD	COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q15596	NCOA2	P27361	MAPK3	S474	M467I	467	Missense	distal	-7	no	16.202	16.188	EPSD	COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q15596	NCOA2	P27361	MAPK3	S474	P470S	470	Missense	distal	-4	no	16.202	16.229	EPSD	COSMIC;GDSC;CCLE	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q15596	NCOA2	P27361	MAPK3	S474	G480R	480	Missense	distal	6	no	16.202	16.192	EPSD	COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q15596	NCOA2	P27361	MAPK3	S487	G480R	480	Missense	distal	-7	no	14.608	14.653	EPSD	COSMIC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q15596	NCOA2	P27361	MAPK3	S565	V567F	567	Missense	proximal	2	no	17.377	17.352	EPSD	COSMIC;GDSC;CCLE	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q15596	NCOA2	P27361	MAPK3	S655	S662L	662	Missense	distal	7	no	14.809	15.079	EPSD	COSMIC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q15596	NCOA2	P27361	MAPK3	S655	P656S	656	Missense	proximal	1	no	14.809	5.756	EPSD	COSMIC	9.358	Loss
CMGC_MAPK_ERK1_MAPK3_ST	Q15596	NCOA2	P27361	MAPK3	S671	G670S	670	Missense	proximal	-1	no	9.373	9.439	EPSD	COSMIC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q15596	NCOA2	P27361	MAPK3	S736	P737S	737	Missense	proximal	1	no	18.552	9.498	PhosphoSitePlus	COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q15596	NCOA2	P27361	MAPK3	T763	D756V	756	Missense	distal	-7	no	14.607	14.714	EPSD	COSMIC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q15596	NCOA2	P27361	MAPK3	S851	A848V	848	Missense	distal	-3	no	17.368	17.387	EPSD	COSMIC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q15596	NCOA2	P27361	MAPK3	S851	E849K	849	Missense	proximal	-2	no	17.368	16.673	EPSD	COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q15596	NCOA2	P27361	MAPK3	S851	G857A	857	Missense	distal	6	no	17.368	17.074	EPSD	COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q15596	NCOA2	P27361	MAPK3	T854	A848V	848	Missense	distal	-6	no	15.982	15.969	EPSD	COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q15596	NCOA2	P27361	MAPK3	T854	E849K	849	Missense	distal	-5	no	15.982	15.970	EPSD	COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q15596	NCOA2	P27361	MAPK3	T854	G857A	857	Missense	distal	3	no	15.982	15.954	EPSD	COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q15596	NCOA2	P27361	MAPK3	S895	T897A	897	Missense	proximal	2	no	18.373	18.345	EPSD	COSMIC;CCLE	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q15596	NCOA2	P27361	MAPK3	S1059	L1064P	1064	Missense	distal	5	no	14.165	14.393	EPSD	COSMIC;CCLE	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q15596	NCOA2	P27361	MAPK3	S1059	P1055L	1055	Missense	distal	-4	no	14.165	14.052	EPSD	COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q15596	NCOA2	P27361	MAPK3	S1072	H1067R	1067	Missense	distal	-5	no	15.613	15.604	EPSD	COSMIC;GDSC;CCLE	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q15596	NCOA2	P27361	MAPK3	S1072	P1073Q	1073	Missense	proximal	1	no	15.613	7.669	EPSD	COSMIC	9.358	Loss
CMGC_MAPK_ERK1_MAPK3_ST	Q15596	NCOA2	P27361	MAPK3	T1273	G1269W	1269	Missense	distal	-4	no	12.431	12.186	EPSD	COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P17676	CEBPB	P27361	MAPK3	S76	H69Q	69	Missense	distal	-7	no	16.206	16.216	EPSD	COSMIC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P36956	SREBF1	P27361	MAPK3	T105	P99S	99	Missense	distal	-6	no	13.759	13.843	EPSD	COSMIC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P36956	SREBF1	P27361	MAPK3	T105	S112A	112	Missense	distal	7	no	13.759	14.104	EPSD	COSMIC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P36956	SREBF1	P27361	MAPK3	T105	P111L	111	Missense	distal	6	no	13.759	13.532	EPSD	COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P36956	SREBF1	P27361	MAPK3	T105	Y110C	110	Missense	distal	5	no	13.759	13.451	EPSD	COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P36956	SREBF1	P27361	MAPK3	T105	P106H	106	Missense	proximal	1	no	13.759	6.003	EPSD	COSMIC	9.358	Loss
CMGC_MAPK_ERK1_MAPK3_ST	P36956	SREBF1	P27361	MAPK3	S117	K123E	123	Missense	distal	6	no	14.822	14.898	PhosphoSitePlus	COSMIC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P36956	SREBF1	P27361	MAPK3	S117	S112A	112	Missense	distal	-5	no	14.822	14.723	PhosphoSitePlus	COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P36956	SREBF1	P27361	MAPK3	S117	P111L	111	Missense	distal	-6	no	14.822	14.575	PhosphoSitePlus	COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P36956	SREBF1	P27361	MAPK3	S117	Y110C	110	Missense	distal	-7	no	14.822	14.973	PhosphoSitePlus	COSMIC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P36956	SREBF1	P27361	MAPK3	S117	G119W	119	Missense	proximal	2	no	14.822	14.766	PhosphoSitePlus	COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P36956	SREBF1	P27361	MAPK3	T426	E420K	420	Missense	distal	-6	no	13.292	13.150	EPSD	COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P36956	SREBF1	P27361	MAPK3	T426	D423G	423	Missense	distal	-3	no	13.292	13.282	EPSD	COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P36956	SREBF1	P27361	MAPK3	S434	P440H	440	Missense	distal	6	no	15.678	15.585	EPSD	COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P36956	SREBF1	P27361	MAPK3	S439	L443F	443	Missense	distal	4	no	17.730	17.519	EPSD	COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P36956	SREBF1	P27361	MAPK3	S439	P440H	440	Missense	proximal	1	no	17.730	9.974	EPSD	COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P36956	SREBF1	P27361	MAPK3	S461	G454D	454	Missense	distal	-7	no	21.242	21.247	EPSD	COSMIC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P36956	SREBF1	P27361	MAPK3	S461	P459H	459	Missense	proximal	-2	no	21.242	20.014	EPSD	COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P36956	SREBF1	P27361	MAPK3	S524	S520N	520	Missense	distal	-4	no	17.382	17.321	EPSD	COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P36956	SREBF1	P27361	MAPK3	S524	G531A	531	Missense	distal	7	no	17.382	17.588	EPSD	COSMIC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P36956	SREBF1	P27361	MAPK3	S524	H523N	523	Missense	proximal	-1	no	17.382	17.372	EPSD	COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P36956	SREBF1	P27361	MAPK3	S1049	T1051I	1051	Missense	proximal	2	no	14.297	14.273	EPSD	COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P36956	SREBF1	P27361	MAPK3	S1049	A1046V	1046	Missense	distal	-3	no	14.297	14.316	EPSD	COSMIC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P36956	SREBF1	P27361	MAPK3	S1049	G1047W	1047	Missense	proximal	-2	no	14.297	13.117	EPSD	COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	O60504	SORBS3	P27361	MAPK3	S24	G20D	20	Missense	distal	-4	no	10.905	10.909	EPSD	COSMIC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	O60504	SORBS3	P27361	MAPK3	S24	P19S	19	Missense	distal	-5	no	10.905	10.910	EPSD	COSMIC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	O60504	SORBS3	P27361	MAPK3	T64	Y63H	63	Missense	proximal	-1	no	13.317	13.354	EPSD	COSMIC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	O60504	SORBS3	P27361	MAPK3	T106	N102K	102	Missense	distal	-4	no	9.482	9.460	EPSD	COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	O60504	SORBS3	P27361	MAPK3	S197	G195E	195	Missense	proximal	-2	no	9.069	9.539	EPSD	COSMIC	9.358	Gain
CMGC_MAPK_ERK1_MAPK3_ST	O60504	SORBS3	P27361	MAPK3	S299	R296M	296	Missense	distal	-3	no	16.716	16.627	EPSD	COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	O60504	SORBS3	P27361	MAPK3	S303	R296M	296	Missense	distal	-7	no	14.827	14.949	EPSD	COSMIC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	O60504	SORBS3	P27361	MAPK3	S339	A344V	344	Missense	distal	5	no	15.206	15.195	EPSD	COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	O60504	SORBS3	P27361	MAPK3	S348	A344V	344	Missense	distal	-4	no	15.273	15.253	EPSD	COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	O60504	SORBS3	P27361	MAPK3	S373	E379K	379	Missense	distal	6	no	14.892	14.816	EPSD	COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	O60504	SORBS3	P27361	MAPK3	S373	E379G	379	Missense	distal	6	no	14.892	14.791	EPSD	COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	O60504	SORBS3	P27361	MAPK3	S395	A393V	393	Missense	proximal	-2	no	15.013	15.710	EPSD	COSMIC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	O60504	SORBS3	P27361	MAPK3	S530	A537T	537	Missense	distal	7	no	16.232	16.004	EPSD	COSMIC;GDSC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	O60504	SORBS3	P27361	MAPK3	S530	D523E	523	Missense	distal	-7	no	16.232	16.221	EPSD	COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	O60504	SORBS3	P27361	MAPK3	S530	R532C	532	Missense	proximal	2	no	16.232	16.183	EPSD	COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	O60504	SORBS3	P27361	MAPK3	S545	S551N	551	Missense	distal	6	no	18.021	17.793	EPSD	COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	O60504	SORBS3	P27361	MAPK3	S545	A540S	540	Missense	distal	-5	no	18.021	18.120	EPSD	COSMIC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	O60504	SORBS3	P27361	MAPK3	S545	R550H	550	Missense	distal	5	no	18.021	18.057	EPSD	COSMIC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	O60504	SORBS3	P27361	MAPK3	S545	A548T	548	Missense	distal	3	no	18.021	18.052	EPSD	COSMIC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	O60504	SORBS3	P27361	MAPK3	S551	S551N	551	Missense	central	0	yes	16.335	0.000	EPSD	COSMIC	9.358	Loss
CMGC_MAPK_ERK1_MAPK3_ST	O60504	SORBS3	P27361	MAPK3	S551	R550H	550	Missense	proximal	-1	no	16.335	16.337	EPSD	COSMIC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	O60504	SORBS3	P27361	MAPK3	S551	A548T	548	Missense	distal	-3	no	16.335	16.396	EPSD	COSMIC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	O60504	SORBS3	P27361	MAPK3	S563	R565H	565	Missense	proximal	2	no	14.694	14.691	EPSD	COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	O60504	SORBS3	P27361	MAPK3	T585	T580I	580	Missense	distal	-5	no	15.686	15.608	EPSD	COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	O60504	SORBS3	P27361	MAPK3	T585	G584D	584	Missense	proximal	-1	no	15.686	15.706	EPSD	COSMIC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	O60504	SORBS3	P27361	MAPK3	S606	G603W	603	Missense	distal	-3	no	16.076	15.903	EPSD	COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P04150	NR3C1	P27361	MAPK3	T8	R11I	11	Missense	distal	3	no	15.349	15.320	EPSD	COSMIC;GDSC;CCLE	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P04150	NR3C1	P27361	MAPK3	T8	P15L	15	Missense	distal	7	no	15.349	15.542	EPSD	COSMIC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P04150	NR3C1	P27361	MAPK3	S17	R23K	23	Missense	distal	6	no	9.363	9.397	EPSD	COSMIC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P04150	NR3C1	P27361	MAPK3	S17	R11I	11	Missense	distal	-6	no	9.363	9.125	EPSD	COSMIC;GDSC;CCLE	9.358	Loss
CMGC_MAPK_ERK1_MAPK3_ST	P04150	NR3C1	P27361	MAPK3	S17	P15L	15	Missense	proximal	-2	no	9.363	7.979	EPSD	COSMIC	9.358	Loss
CMGC_MAPK_ERK1_MAPK3_ST	P04150	NR3C1	P27361	MAPK3	S45	A49V	49	Missense	distal	4	no	14.239	14.347	EPSD	COSMIC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P04150	NR3C1	P27361	MAPK3	S203	T208A	208	Missense	distal	5	no	15.329	15.210	EPSD	COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P04150	NR3C1	P27361	MAPK3	S211	T208A	208	Missense	distal	-3	no	15.027	14.966	EPSD	COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P04150	NR3C1	P27361	MAPK3	S267	P268L	268	Missense	proximal	1	no	16.626	7.588	EPSD	COSMIC	9.358	Loss
CMGC_MAPK_ERK1_MAPK3_ST	P04150	NR3C1	P27361	MAPK3	T288	E285K	285	Missense	distal	-3	no	14.563	14.532	EPSD	COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P04150	NR3C1	P27361	MAPK3	S395	Y393H	393	Missense	proximal	-2	no	16.269	16.351	EPSD	COSMIC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P04150	NR3C1	P27361	MAPK3	S404	P405T	405	Missense	proximal	1	no	15.097	6.220	EPSD	COSMIC	9.358	Loss
CMGC_MAPK_ERK1_MAPK3_ST	P04150	NR3C1	P27361	MAPK3	S408	G415V	415	Missense	distal	7	no	11.181	11.360	EPSD	COSMIC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P04150	NR3C1	P27361	MAPK3	S408	P405T	405	Missense	distal	-3	no	11.181	11.143	EPSD	COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P04150	NR3C1	P27361	MAPK3	T413	G415V	415	Missense	proximal	2	no	9.451	9.442	EPSD	COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P04150	NR3C1	P27361	MAPK3	S650	S651F	651	Missense	proximal	1	no	7.707	10.546	EPSD	COSMIC	9.358	Gain
CMGC_MAPK_ERK1_MAPK3_ST	P43364	MAGEA11	P27361	MAPK3	S13	R19K	19	Missense	distal	6	no	16.354	16.388	EPSD	COSMIC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P43364	MAGEA11	P27361	MAPK3	S13	L10V	10	Missense	distal	-3	no	16.354	16.357	EPSD	COSMIC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P43364	MAGEA11	P27361	MAPK3	S13	R6C	6	Missense	distal	-7	no	16.354	16.541	EPSD	COSMIC;CCLE	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P43364	MAGEA11	P27361	MAPK3	S76	R79T	79	Missense	distal	3	no	15.314	15.323	EPSD	COSMIC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P43364	MAGEA11	P27361	MAPK3	S76	P77S	77	Missense	proximal	1	no	15.314	6.261	EPSD	COSMIC	9.358	Loss
CMGC_MAPK_ERK1_MAPK3_ST	P43364	MAGEA11	P27361	MAPK3	S174	S179L	179	Missense	distal	5	no	17.385	17.114	PhosphoSitePlus	COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P43364	MAGEA11	P27361	MAPK3	S181	S179L	179	Missense	proximal	-2	no	15.962	15.654	EPSD	COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P43364	MAGEA11	P27361	MAPK3	S181	D186N	186	Missense	distal	5	no	15.962	15.881	EPSD	COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P43364	MAGEA11	P27361	MAPK3	S208	G204R	204	Missense	distal	-4	no	15.720	15.682	EPSD	COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P43364	MAGEA11	P27361	MAPK3	S216	D220Y	220	Missense	distal	4	no	12.555	12.458	EPSD	COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P43364	MAGEA11	P27361	MAPK3	S216	F217L	217	Missense	proximal	1	no	12.555	9.730	EPSD	COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P10242	MYB	P27361	MAPK3	S370	V377A	377	Missense	distal	7	no	15.888	15.916	EPSD	COSMIC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P10242	MYB	P27361	MAPK3	S370	S363F	363	Missense	distal	-7	no	15.888	16.108	EPSD	COSMIC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P10242	MYB	P27361	MAPK3	S370	S370L	370	Missense	central	0	yes	15.888	0.000	EPSD	COSMIC	9.358	Loss
CMGC_MAPK_ERK1_MAPK3_ST	P10242	MYB	P27361	MAPK3	S370	A369T	369	Missense	proximal	-1	no	15.888	15.992	EPSD	COSMIC;GDSC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P10242	MYB	P27361	MAPK3	T420	S421F	421	Missense	proximal	1	no	7.123	9.962	EPSD	COSMIC	9.358	Gain
CMGC_MAPK_ERK1_MAPK3_ST	P10242	MYB	P27361	MAPK3	T433	F435L	435	Missense	proximal	2	no	13.926	13.953	EPSD	COSMIC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P10242	MYB	P27361	MAPK3	T433	P434L	434	Missense	proximal	1	no	13.926	4.888	EPSD	COSMIC	9.358	Loss
CMGC_MAPK_ERK1_MAPK3_ST	P10242	MYB	P27361	MAPK3	T433	T430A	430	Missense	distal	-3	no	13.926	13.864	EPSD	COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P10242	MYB	P27361	MAPK3	T433	T432A	432	Missense	proximal	-1	no	13.926	13.822	EPSD	COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P10242	MYB	P27361	MAPK3	T433	R437K	437	Missense	distal	4	no	13.926	13.934	EPSD	COSMIC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P10242	MYB	P27361	MAPK3	T433	T433A	433	Missense	central	0	yes	13.926	0.000	EPSD	COSMIC	9.358	Loss
CMGC_MAPK_ERK1_MAPK3_ST	P10242	MYB	P27361	MAPK3	T452	P453T	453	Missense	proximal	1	no	14.557	5.680	EPSD	COSMIC	9.358	Loss
CMGC_MAPK_ERK1_MAPK3_ST	P10242	MYB	P27361	MAPK3	T452	R451H	451	Missense	proximal	-1	no	14.557	14.560	EPSD	COSMIC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P10242	MYB	P27361	MAPK3	S463	F470L	470	Missense	distal	7	no	15.643	15.422	EPSD	COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P10242	MYB	P27361	MAPK3	S463	P464R	464	Missense	proximal	1	no	15.643	6.142	EPSD	COSMIC	9.358	Loss
CMGC_MAPK_ERK1_MAPK3_ST	P10242	MYB	P27361	MAPK3	S463	P469L	469	Missense	distal	6	no	15.643	15.416	EPSD	COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P10242	MYB	P27361	MAPK3	S463	R465K	465	Missense	proximal	2	no	15.643	15.639	EPSD	COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P10242	MYB	P27361	MAPK3	S463	P464L	464	Missense	proximal	1	no	15.643	6.605	EPSD	COSMIC	9.358	Loss
CMGC_MAPK_ERK1_MAPK3_ST	P10242	MYB	P27361	MAPK3	S463	S462T	462	Missense	proximal	-1	no	15.643	15.613	EPSD	COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P10242	MYB	P27361	MAPK3	S463	R465Q	465	Missense	proximal	2	no	15.643	15.634	EPSD	COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P10242	MYB	P27361	MAPK3	T466	F470L	470	Missense	distal	4	no	16.505	16.716	EPSD	COSMIC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P10242	MYB	P27361	MAPK3	T466	P464R	464	Missense	proximal	-2	no	16.505	15.105	EPSD	COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P10242	MYB	P27361	MAPK3	T466	P469L	469	Missense	distal	3	no	16.505	16.468	EPSD	COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P10242	MYB	P27361	MAPK3	T466	R465K	465	Missense	proximal	-1	no	16.505	16.492	EPSD	COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P10242	MYB	P27361	MAPK3	T466	P464L	464	Missense	proximal	-2	no	16.505	15.121	EPSD	COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P10242	MYB	P27361	MAPK3	T466	A473S	473	Missense	distal	7	no	16.505	16.159	EPSD	COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P10242	MYB	P27361	MAPK3	T466	S462T	462	Missense	distal	-4	no	16.505	16.447	EPSD	COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P10242	MYB	P27361	MAPK3	T466	R465Q	465	Missense	proximal	-1	no	16.505	16.466	EPSD	COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P10242	MYB	P27361	MAPK3	T468	F470L	470	Missense	proximal	2	no	14.934	14.961	EPSD	COSMIC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P10242	MYB	P27361	MAPK3	T468	P464R	464	Missense	distal	-4	no	14.934	14.884	EPSD	COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P10242	MYB	P27361	MAPK3	T468	P469L	469	Missense	proximal	1	no	14.934	5.896	EPSD	COSMIC	9.358	Loss
CMGC_MAPK_ERK1_MAPK3_ST	P10242	MYB	P27361	MAPK3	T468	R465K	465	Missense	distal	-3	no	14.934	14.921	EPSD	COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P10242	MYB	P27361	MAPK3	T468	P464L	464	Missense	distal	-4	no	14.934	14.821	EPSD	COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P10242	MYB	P27361	MAPK3	T468	A473S	473	Missense	distal	5	no	14.934	15.189	EPSD	COSMIC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P10242	MYB	P27361	MAPK3	T468	S462T	462	Missense	distal	-6	no	14.934	14.765	EPSD	COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P10242	MYB	P27361	MAPK3	T468	R465Q	465	Missense	distal	-3	no	14.934	14.926	EPSD	COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P10242	MYB	P27361	MAPK3	T490	D497Y	497	Missense	distal	7	no	15.901	16.049	EPSD	COSMIC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P10242	MYB	P27361	MAPK3	T490	L494V	494	Missense	distal	4	no	15.901	15.881	EPSD	COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P10242	MYB	P27361	MAPK3	S532	E531K	531	Missense	proximal	-1	no	16.221	16.190	PhosphoSitePlus	COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P10242	MYB	P27361	MAPK3	S532	I526F	526	Missense	distal	-6	no	16.221	16.152	PhosphoSitePlus	COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P10242	MYB	P27361	MAPK3	S532	I526S	526	Missense	distal	-6	no	16.221	16.619	PhosphoSitePlus	COSMIC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P10242	MYB	P27361	MAPK3	S532	E529D	529	Missense	distal	-3	no	16.221	16.217	PhosphoSitePlus	COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P10242	MYB	P27361	MAPK3	S532	S532F	532	Missense	central	0	yes	16.221	0.000	PhosphoSitePlus	COSMIC;CCLE	9.358	Loss
CMGC_MAPK_ERK1_MAPK3_ST	P10242	MYB	P27361	MAPK3	S532	P533L	533	Missense	proximal	1	no	16.221	7.183	PhosphoSitePlus	COSMIC	9.358	Loss
CMGC_MAPK_ERK1_MAPK3_ST	P10242	MYB	P27361	MAPK3	S532	P533S	533	Missense	proximal	1	no	16.221	7.167	PhosphoSitePlus	COSMIC	9.358	Loss
CMGC_MAPK_ERK1_MAPK3_ST	P10242	MYB	P27361	MAPK3	S560	A563S	563	Missense	distal	3	no	15.465	15.509	EPSD	COSMIC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P10242	MYB	P27361	MAPK3	S560	T553A	553	Missense	distal	-7	no	15.465	15.538	EPSD	COSMIC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P10242	MYB	P27361	MAPK3	S560	P566R	566	Missense	distal	6	no	15.465	15.353	EPSD	COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P10242	MYB	P27361	MAPK3	S560	T553K	553	Missense	distal	-7	no	15.465	15.472	EPSD	COSMIC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P10242	MYB	P27361	MAPK3	S560	S560L	560	Missense	central	0	yes	15.465	0.000	EPSD	COSMIC	9.358	Loss
CMGC_MAPK_ERK1_MAPK3_ST	P10242	MYB	P27361	MAPK3	S560	T557M	557	Missense	distal	-3	no	15.465	15.368	EPSD	COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P10242	MYB	P27361	MAPK3	S599	P600R	600	Missense	proximal	1	no	13.762	4.262	EPSD	COSMIC	9.358	Loss
CMGC_MAPK_ERK1_MAPK3_ST	P10242	MYB	P27361	MAPK3	S599	A598S	598	Missense	proximal	-1	no	13.762	13.896	EPSD	COSMIC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P10242	MYB	P27361	MAPK3	S599	P603R	603	Missense	distal	4	no	13.762	13.665	EPSD	COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P10242	MYB	P27361	MAPK3	S599	S606T	606	Missense	distal	7	no	13.762	13.881	EPSD	COSMIC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P10242	MYB	P27361	MAPK3	S599	C604R	604	Missense	distal	5	no	13.762	14.142	EPSD	COSMIC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P10242	MYB	P27361	MAPK3	S605	P600R	600	Missense	distal	-5	no	9.681	9.641	EPSD	COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P10242	MYB	P27361	MAPK3	S605	E609V	609	Missense	distal	4	no	9.681	9.558	EPSD	COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P10242	MYB	P27361	MAPK3	S605	A598S	598	Missense	distal	-7	no	9.681	9.531	EPSD	COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P10242	MYB	P27361	MAPK3	S605	P610T	610	Missense	distal	5	no	9.681	9.589	EPSD	COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P10242	MYB	P27361	MAPK3	S605	P603R	603	Missense	proximal	-2	no	9.681	8.281	EPSD	COSMIC	9.358	Loss
CMGC_MAPK_ERK1_MAPK3_ST	P10242	MYB	P27361	MAPK3	S605	A611V	611	Missense	distal	6	no	9.681	9.768	EPSD	COSMIC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P10242	MYB	P27361	MAPK3	S605	S606T	606	Missense	proximal	1	no	9.681	9.858	EPSD	COSMIC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P10242	MYB	P27361	MAPK3	S605	C604R	604	Missense	proximal	-1	no	9.681	9.866	EPSD	COSMIC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P10242	MYB	P27361	MAPK3	S624	Y629H	629	Missense	distal	5	no	9.371	9.479	EPSD	COSMIC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P10242	MYB	P27361	MAPK3	S624	S623F	623	Missense	proximal	-1	no	9.371	9.166	EPSD	COSMIC	9.358	Loss
CMGC_MAPK_ERK1_MAPK3_ST	P10242	MYB	P27361	MAPK3	S624	T621I	621	Missense	distal	-3	no	9.371	9.289	EPSD	COSMIC	9.358	Loss
CMGC_MAPK_ERK1_MAPK3_ST	P10242	MYB	P27361	MAPK3	S624	M620I	620	Missense	distal	-4	no	9.371	9.391	EPSD	COSMIC;CCLE	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P10242	MYB	P27361	MAPK3	S624	S624R	624	Missense	central	0	yes	9.371	0.000	EPSD	COSMIC	9.358	Loss
CMGC_MAPK_ERK1_MAPK3_ST	P35568	IRS1	P27361	MAPK3	S3	G9D	9	Missense	distal	6	no	13.892	13.948	EPSD	COSMIC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P35568	IRS1	P27361	MAPK3	S193	K190N	190	Missense	distal	-3	no	13.681	13.688	EPSD	COSMIC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P35568	IRS1	P27361	MAPK3	S193	S189N	189	Missense	distal	-4	no	13.681	13.620	EPSD	COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P35568	IRS1	P27361	MAPK3	S273	S274P	274	Missense	proximal	1	no	6.022	15.075	EPSD	COSMIC	9.358	Gain
CMGC_MAPK_ERK1_MAPK3_ST	P35568	IRS1	P27361	MAPK3	S295	R301C	301	Missense	distal	6	no	10.617	9.991	EPSD	COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P35568	IRS1	P27361	MAPK3	S295	Q296R	296	Missense	proximal	1	no	10.617	9.060	EPSD	COSMIC;GDSC	9.358	Loss
CMGC_MAPK_ERK1_MAPK3_ST	P35568	IRS1	P27361	MAPK3	S295	R302L	302	Missense	distal	7	no	10.617	10.717	EPSD	COSMIC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P35568	IRS1	P27361	MAPK3	S295	L289F	289	Missense	distal	-6	no	10.617	10.481	EPSD	COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P35568	IRS1	P27361	MAPK3	S295	P292S	292	Missense	distal	-3	no	10.617	10.608	EPSD	COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P35568	IRS1	P27361	MAPK3	S295	P294T	294	Missense	proximal	-1	no	10.617	10.581	EPSD	COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P35568	IRS1	P27361	MAPK3	S312	E306K	306	Missense	distal	-6	no	14.927	14.786	EPSD	COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P35568	IRS1	P27361	MAPK3	S312	A310T	310	Missense	proximal	-2	no	14.927	16.292	EPSD	COSMIC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P35568	IRS1	P27361	MAPK3	S312	P313L	313	Missense	proximal	1	no	14.927	5.889	EPSD	COSMIC;GDSC;CCLE	9.358	Loss
CMGC_MAPK_ERK1_MAPK3_ST	P35568	IRS1	P27361	MAPK3	S312	M316V	316	Missense	distal	4	no	14.927	15.082	EPSD	COSMIC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P35568	IRS1	P27361	MAPK3	S312	M316I	316	Missense	distal	4	no	14.927	14.965	EPSD	COSMIC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P35568	IRS1	P27361	MAPK3	S312	I308M	308	Missense	distal	-4	no	14.927	14.907	EPSD	COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P35568	IRS1	P27361	MAPK3	S312	A310V	310	Missense	proximal	-2	no	14.927	15.624	EPSD	COSMIC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P35568	IRS1	P27361	MAPK3	S323	R327L	327	Missense	distal	4	no	10.232	10.175	EPSD	COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P35568	IRS1	P27361	MAPK3	S323	R325H	325	Missense	proximal	2	no	10.232	10.229	EPSD	COSMIC;CCLE	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P35568	IRS1	P27361	MAPK3	S323	R327C	327	Missense	distal	4	no	10.232	9.875	EPSD	COSMIC;CCLE	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P35568	IRS1	P27361	MAPK3	S323	M316V	316	Missense	distal	-7	no	10.232	10.176	EPSD	COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P35568	IRS1	P27361	MAPK3	S323	M316I	316	Missense	distal	-7	no	10.232	10.218	EPSD	COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P35568	IRS1	P27361	MAPK3	S323	R325C	325	Missense	proximal	2	no	10.232	10.183	EPSD	COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P35568	IRS1	P27361	MAPK3	S323	F324L	324	Missense	proximal	1	no	10.232	7.407	EPSD	COSMIC	9.358	Loss
CMGC_MAPK_ERK1_MAPK3_ST	P35568	IRS1	P27361	MAPK3	S345	S341L	341	Missense	distal	-4	no	17.160	17.020	EPSD	COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P35568	IRS1	P27361	MAPK3	S345	N352D	352	Missense	distal	7	no	17.160	17.101	EPSD	COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P35568	IRS1	P27361	MAPK3	S345	P349L	349	Missense	distal	4	no	17.160	17.006	EPSD	COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P35568	IRS1	P27361	MAPK3	S345	P346S	346	Missense	proximal	1	no	17.160	8.107	EPSD	COSMIC	9.358	Loss
CMGC_MAPK_ERK1_MAPK3_ST	P35568	IRS1	P27361	MAPK3	S348	S341L	341	Missense	distal	-7	no	17.318	17.463	EPSD	COSMIC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P35568	IRS1	P27361	MAPK3	S348	N352D	352	Missense	distal	4	no	17.318	17.345	EPSD	COSMIC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P35568	IRS1	P27361	MAPK3	S348	P349L	349	Missense	proximal	1	no	17.318	8.280	EPSD	COSMIC	9.358	Loss
CMGC_MAPK_ERK1_MAPK3_ST	P35568	IRS1	P27361	MAPK3	S348	P346S	346	Missense	proximal	-2	no	17.318	16.242	EPSD	COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P35568	IRS1	P27361	MAPK3	S383	A379P	379	Missense	distal	-4	no	16.168	16.272	EPSD	COSMIC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P35568	IRS1	P27361	MAPK3	S383	S383L	383	Missense	central	0	yes	16.168	0.000	EPSD	COSMIC	9.358	Loss
CMGC_MAPK_ERK1_MAPK3_ST	P35568	IRS1	P27361	MAPK3	S383	R381L	381	Missense	proximal	-2	no	16.168	16.184	EPSD	COSMIC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P35568	IRS1	P27361	MAPK3	S383	S383W	383	Missense	central	0	yes	16.168	0.000	EPSD	COSMIC	9.358	Loss
CMGC_MAPK_ERK1_MAPK3_ST	P35568	IRS1	P27361	MAPK3	S383	P384S	384	Missense	proximal	1	no	16.168	7.114	EPSD	COSMIC	9.358	Loss
CMGC_MAPK_ERK1_MAPK3_ST	P35568	IRS1	P27361	MAPK3	S383	S385L	385	Missense	proximal	2	no	16.168	16.145	EPSD	COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P35568	IRS1	P27361	MAPK3	S388	S383L	383	Missense	distal	-5	no	13.889	13.829	EPSD	COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P35568	IRS1	P27361	MAPK3	S388	R381L	381	Missense	distal	-7	no	13.889	13.951	EPSD	COSMIC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P35568	IRS1	P27361	MAPK3	S388	S383W	383	Missense	distal	-5	no	13.889	13.690	EPSD	COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P35568	IRS1	P27361	MAPK3	S388	S395I	395	Missense	distal	7	no	13.889	14.287	EPSD	COSMIC;GDSC;CCLE	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P35568	IRS1	P27361	MAPK3	S388	P384S	384	Missense	distal	-4	no	13.889	13.916	EPSD	COSMIC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P35568	IRS1	P27361	MAPK3	S388	S385L	385	Missense	distal	-3	no	13.889	13.813	EPSD	COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P35568	IRS1	P27361	MAPK3	S419	S415L	415	Missense	distal	-4	no	14.960	14.820	EPSD	COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P35568	IRS1	P27361	MAPK3	S419	G418V	418	Missense	proximal	-1	no	14.960	14.942	EPSD	COSMIC;GDSC;CCLE	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P35568	IRS1	P27361	MAPK3	S419	D422N	422	Missense	distal	3	no	14.960	14.950	EPSD	COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P35568	IRS1	P27361	MAPK3	S419	G423C	423	Missense	distal	4	no	14.960	14.617	EPSD	COSMIC;GDSC;CCLE	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P35568	IRS1	P27361	MAPK3	S419	G424C	424	Missense	distal	5	no	14.960	14.502	EPSD	COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P35568	IRS1	P27361	MAPK3	S434	P435L	435	Missense	proximal	1	no	15.936	6.898	EPSD	COSMIC	9.358	Loss
CMGC_MAPK_ERK1_MAPK3_ST	P35568	IRS1	P27361	MAPK3	S434	R439Q	439	Missense	distal	5	no	15.936	15.935	EPSD	COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P35568	IRS1	P27361	MAPK3	S434	S441Y	441	Missense	distal	7	no	15.936	16.191	EPSD	COSMIC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P35568	IRS1	P27361	MAPK3	S434	S434G	434	Missense	central	0	yes	15.936	0.000	EPSD	COSMIC	9.358	Loss
CMGC_MAPK_ERK1_MAPK3_ST	P35568	IRS1	P27361	MAPK3	S434	S441F	441	Missense	distal	7	no	15.936	16.427	EPSD	COSMIC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P35568	IRS1	P27361	MAPK3	S434	P435F	435	Missense	proximal	1	no	15.936	9.723	EPSD	COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P35568	IRS1	P27361	MAPK3	T446	G451C	451	Missense	distal	5	no	15.156	14.698	EPSD	COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P35568	IRS1	P27361	MAPK3	T446	D448E	448	Missense	proximal	2	no	15.156	15.159	EPSD	COSMIC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P35568	IRS1	P27361	MAPK3	T446	S441Y	441	Missense	distal	-5	no	15.156	15.093	EPSD	COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P35568	IRS1	P27361	MAPK3	T446	T453I	453	Missense	distal	7	no	15.156	15.436	EPSD	COSMIC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P35568	IRS1	P27361	MAPK3	T446	S441F	441	Missense	distal	-5	no	15.156	15.022	EPSD	COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P35568	IRS1	P27361	MAPK3	T446	R443C	443	Missense	distal	-3	no	15.156	15.016	EPSD	COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P35568	IRS1	P27361	MAPK3	T446	P447L	447	Missense	proximal	1	no	15.156	6.118	EPSD	COSMIC	9.358	Loss
CMGC_MAPK_ERK1_MAPK3_ST	P35568	IRS1	P27361	MAPK3	T446	R443L	443	Missense	distal	-3	no	15.156	15.119	EPSD	COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P35568	IRS1	P27361	MAPK3	T446	S444I	444	Missense	proximal	-2	no	15.156	14.394	EPSD	COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P35568	IRS1	P27361	MAPK3	T446	S449P	449	Missense	distal	3	no	15.156	15.161	EPSD	COSMIC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P35568	IRS1	P27361	MAPK3	T453	G451C	451	Missense	proximal	-2	no	15.804	14.405	EPSD	COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P35568	IRS1	P27361	MAPK3	T453	E460K	460	Missense	distal	7	no	15.804	15.875	EPSD	COSMIC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P35568	IRS1	P27361	MAPK3	T453	G458A	458	Missense	distal	5	no	15.804	15.614	EPSD	COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P35568	IRS1	P27361	MAPK3	T453	T453I	453	Missense	central	0	yes	15.804	0.000	EPSD	COSMIC	9.358	Loss
CMGC_MAPK_ERK1_MAPK3_ST	P35568	IRS1	P27361	MAPK3	T453	P447L	447	Missense	distal	-6	no	15.804	15.557	EPSD	COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P35568	IRS1	P27361	MAPK3	T453	S449P	449	Missense	distal	-4	no	15.804	15.777	EPSD	COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P35568	IRS1	P27361	MAPK3	T495	T495A	495	Missense	central	0	yes	17.120	0.000	EPSD	COSMIC	9.358	Loss
CMGC_MAPK_ERK1_MAPK3_ST	P35568	IRS1	P27361	MAPK3	T495	G489D	489	Missense	distal	-6	no	17.120	17.122	EPSD	COSMIC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P35568	IRS1	P27361	MAPK3	T495	G497E	497	Missense	proximal	2	no	17.120	17.128	EPSD	COSMIC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P35568	IRS1	P27361	MAPK3	T495	H492Y	492	Missense	distal	-3	no	17.120	17.088	EPSD	COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P35568	IRS1	P27361	MAPK3	S503	G497E	497	Missense	distal	-6	no	14.163	14.209	EPSD	COSMIC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P35568	IRS1	P27361	MAPK3	S531	T530A	530	Missense	proximal	-1	no	14.834	14.731	EPSD	COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P35568	IRS1	P27361	MAPK3	S531	T533I	533	Missense	proximal	2	no	14.834	14.810	EPSD	COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P35568	IRS1	P27361	MAPK3	S531	H536N	536	Missense	distal	5	no	14.834	14.820	EPSD	COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P35568	IRS1	P27361	MAPK3	S531	H526Y	526	Missense	distal	-5	no	14.834	14.807	EPSD	COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P35568	IRS1	P27361	MAPK3	S531	G529D	529	Missense	proximal	-2	no	14.834	15.344	EPSD	COSMIC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P35568	IRS1	P27361	MAPK3	S531	T535A	535	Missense	distal	4	no	14.834	14.616	EPSD	COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P35568	IRS1	P27361	MAPK3	S531	Q537R	537	Missense	distal	6	no	14.834	14.904	EPSD	COSMIC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P35568	IRS1	P27361	MAPK3	S603	H598R	598	Missense	distal	-5	no	9.681	9.671	EPSD	COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P35568	IRS1	P27361	MAPK3	S603	G596E	596	Missense	distal	-7	no	9.681	9.675	EPSD	COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P35568	IRS1	P27361	MAPK3	S603	H599Y	599	Missense	distal	-4	no	9.681	9.640	EPSD	COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P35568	IRS1	P27361	MAPK3	S603	H599Q	599	Missense	distal	-4	no	9.681	9.677	EPSD	COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P35568	IRS1	P27361	MAPK3	S616	V622M	622	Missense	distal	6	no	18.082	17.871	PhosphoSitePlus	COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P35568	IRS1	P27361	MAPK3	S616	P614A	614	Missense	proximal	-2	no	18.082	15.731	PhosphoSitePlus	COSMIC;CCLE	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P35568	IRS1	P27361	MAPK3	S636	V640I	640	Missense	distal	4	no	16.332	16.214	EPSD	COSMIC;GDSC;CCLE	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P35568	IRS1	P27361	MAPK3	S636	A642T	642	Missense	distal	6	no	16.332	16.702	EPSD	COSMIC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P35568	IRS1	P27361	MAPK3	S636	G630E	630	Missense	distal	-6	no	16.332	16.377	EPSD	COSMIC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P35568	IRS1	P27361	MAPK3	S666	G661D	661	Missense	distal	-5	no	13.469	13.478	EPSD	COSMIC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P35568	IRS1	P27361	MAPK3	S666	G669S	669	Missense	distal	3	no	13.469	13.485	EPSD	COSMIC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P35568	IRS1	P27361	MAPK3	S666	M664I	664	Missense	proximal	-2	no	13.469	14.385	EPSD	COSMIC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P35568	IRS1	P27361	MAPK3	S672	G677D	677	Missense	distal	5	no	15.175	15.198	EPSD	COSMIC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P35568	IRS1	P27361	MAPK3	S672	G669S	669	Missense	distal	-3	no	15.175	15.207	EPSD	COSMIC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P35568	IRS1	P27361	MAPK3	S672	G677V	677	Missense	distal	5	no	15.175	14.973	EPSD	COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P35568	IRS1	P27361	MAPK3	S672	P679T	679	Missense	distal	7	no	15.175	15.216	EPSD	COSMIC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P35568	IRS1	P27361	MAPK3	S672	P679L	679	Missense	distal	7	no	15.175	15.367	EPSD	COSMIC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P35568	IRS1	P27361	MAPK3	S694	Y695F	695	Missense	proximal	1	no	8.531	9.366	EPSD	COSMIC;GDSC	9.358	Gain
CMGC_MAPK_ERK1_MAPK3_ST	P35568	IRS1	P27361	MAPK3	S736	D731G	731	Missense	distal	-5	no	15.159	15.150	EPSD	COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P35568	IRS1	P27361	MAPK3	S736	V738G	738	Missense	proximal	2	no	15.159	15.168	EPSD	COSMIC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P35568	IRS1	P27361	MAPK3	S736	G739E	739	Missense	distal	3	no	15.159	15.161	EPSD	COSMIC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P35568	IRS1	P27361	MAPK3	S736	N734I	734	Missense	proximal	-2	no	15.159	15.341	EPSD	COSMIC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P35568	IRS1	P27361	MAPK3	S736	N734K	734	Missense	proximal	-2	no	15.159	14.839	EPSD	COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P35568	IRS1	P27361	MAPK3	S745	V738G	738	Missense	distal	-7	no	15.265	15.154	EPSD	COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P35568	IRS1	P27361	MAPK3	S745	G739E	739	Missense	distal	-6	no	15.265	15.311	EPSD	COSMIC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P35568	IRS1	P27361	MAPK3	S892	L885Q	885	Missense	distal	-7	no	18.854	18.791	EPSD	COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P35568	IRS1	P27361	MAPK3	S918	P912L	912	Missense	distal	-6	no	15.353	15.106	EPSD	COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P35568	IRS1	P27361	MAPK3	S918	V913L	913	Missense	distal	-5	no	15.353	15.369	EPSD	COSMIC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P35568	IRS1	P27361	MAPK3	S918	H916Y	916	Missense	proximal	-2	no	15.353	15.271	EPSD	COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P35568	IRS1	P27361	MAPK3	S918	G911D	911	Missense	distal	-7	no	15.353	15.358	EPSD	COSMIC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P35568	IRS1	P27361	MAPK3	S1000	R998C	998	Missense	proximal	-2	no	10.799	8.683	EPSD	COSMIC;GDSC;CCLE	9.358	Loss
CMGC_MAPK_ERK1_MAPK3_ST	P35568	IRS1	P27361	MAPK3	S1000	D1003H	1003	Missense	distal	3	no	10.799	10.795	EPSD	COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P35568	IRS1	P27361	MAPK3	S1000	P997S	997	Missense	distal	-3	no	10.799	10.790	EPSD	COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P35568	IRS1	P27361	MAPK3	S1005	S1011I	1011	Missense	distal	6	no	15.382	14.813	EPSD	COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P35568	IRS1	P27361	MAPK3	S1005	R998C	998	Missense	distal	-7	no	15.382	15.569	EPSD	COSMIC;GDSC;CCLE	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P35568	IRS1	P27361	MAPK3	S1005	D1003H	1003	Missense	proximal	-2	no	15.382	15.762	EPSD	COSMIC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P35568	IRS1	P27361	MAPK3	S1005	P1009S	1009	Missense	distal	4	no	15.382	15.431	EPSD	COSMIC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P35568	IRS1	P27361	MAPK3	S1011	S1011I	1011	Missense	central	0	yes	9.596	0.000	EPSD	COSMIC	9.358	Loss
CMGC_MAPK_ERK1_MAPK3_ST	P35568	IRS1	P27361	MAPK3	S1011	P1009S	1009	Missense	proximal	-2	no	9.596	8.520	EPSD	COSMIC	9.358	Loss
CMGC_MAPK_ERK1_MAPK3_ST	P35568	IRS1	P27361	MAPK3	S1011	D1014G	1014	Missense	distal	3	no	9.596	9.591	EPSD	COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P35568	IRS1	P27361	MAPK3	S1043	A1042T	1042	Missense	proximal	-1	no	16.583	16.686	EPSD	COSMIC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P35568	IRS1	P27361	MAPK3	S1043	A1050V	1050	Missense	distal	7	no	16.583	16.555	EPSD	COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P35568	IRS1	P27361	MAPK3	S1043	S1043F	1043	Missense	central	0	yes	16.583	0.000	EPSD	COSMIC	9.358	Loss
CMGC_MAPK_ERK1_MAPK3_ST	P35568	IRS1	P27361	MAPK3	S1078	P1079S	1079	Missense	proximal	1	no	14.980	5.926	EPSD	COSMIC	9.358	Loss
CMGC_MAPK_ERK1_MAPK3_ST	P35568	IRS1	P27361	MAPK3	S1078	S1078I	1078	Missense	central	0	yes	14.980	0.000	EPSD	COSMIC	9.358	Loss
CMGC_MAPK_ERK1_MAPK3_ST	P35568	IRS1	P27361	MAPK3	S1078	R1074L	1074	Missense	distal	-4	no	14.980	14.916	EPSD	COSMIC;CCLE	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P35568	IRS1	P27361	MAPK3	S1078	R1074Q	1074	Missense	distal	-4	no	14.980	14.990	EPSD	COSMIC;GDSC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P35568	IRS1	P27361	MAPK3	S1078	R1081C	1081	Missense	distal	3	no	14.980	14.916	EPSD	COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P35568	IRS1	P27361	MAPK3	T1107	E1102K	1102	Missense	distal	-5	no	14.450	14.438	EPSD	COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P35568	IRS1	P27361	MAPK3	S1145	R1140C	1140	Missense	distal	-5	no	11.323	11.207	EPSD	COSMIC;CCLE	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P35568	IRS1	P27361	MAPK3	S1145	R1152S	1152	Missense	distal	7	no	11.323	11.154	EPSD	COSMIC;GDSC;CCLE	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P35568	IRS1	P27361	MAPK3	S1145	R1152M	1152	Missense	distal	7	no	11.323	11.604	EPSD	COSMIC;GDSC;CCLE	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P35568	IRS1	P27361	MAPK3	T1196	P1202L	1202	Missense	distal	6	no	15.427	15.200	EPSD	COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P35568	IRS1	P27361	MAPK3	S1218	G1212V	1212	Missense	distal	-6	no	10.887	10.619	EPSD	COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P35568	IRS1	P27361	MAPK3	S1218	R1220C	1220	Missense	proximal	2	no	10.887	10.838	EPSD	COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P35568	IRS1	P27361	MAPK3	S1218	D1225Y	1225	Missense	distal	7	no	10.887	11.035	EPSD	COSMIC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P35568	IRS1	P27361	MAPK3	S1218	E1224Q	1224	Missense	distal	6	no	10.887	10.707	EPSD	COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P35568	IRS1	P27361	MAPK3	T1219	G1212V	1212	Missense	distal	-7	no	10.236	10.347	EPSD	COSMIC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P35568	IRS1	P27361	MAPK3	T1219	R1220C	1220	Missense	proximal	1	no	10.236	4.428	EPSD	COSMIC	9.358	Loss
CMGC_MAPK_ERK1_MAPK3_ST	P35568	IRS1	P27361	MAPK3	T1219	D1225Y	1225	Missense	distal	6	no	10.236	10.030	EPSD	COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P35568	IRS1	P27361	MAPK3	T1219	E1224Q	1224	Missense	distal	5	no	10.236	10.114	EPSD	COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P35568	IRS1	P27361	MAPK3	T1219	L1226V	1226	Missense	distal	7	no	10.236	10.284	EPSD	COSMIC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P35568	IRS1	P27361	MAPK3	S1222	R1220C	1220	Missense	proximal	-2	no	12.032	9.916	EPSD	COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P35568	IRS1	P27361	MAPK3	S1222	D1225Y	1225	Missense	distal	3	no	12.032	12.013	EPSD	COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P35568	IRS1	P27361	MAPK3	S1222	A1228V	1228	Missense	distal	6	no	12.032	12.119	EPSD	COSMIC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P35568	IRS1	P27361	MAPK3	S1222	E1224Q	1224	Missense	proximal	2	no	12.032	12.019	EPSD	COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P35568	IRS1	P27361	MAPK3	S1222	L1226V	1226	Missense	distal	4	no	12.032	12.012	EPSD	COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P35568	IRS1	P27361	MAPK3	S1223	R1220C	1220	Missense	distal	-3	no	11.468	11.328	EPSD	COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P35568	IRS1	P27361	MAPK3	S1223	D1225Y	1225	Missense	proximal	2	no	11.468	11.458	EPSD	COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P35568	IRS1	P27361	MAPK3	S1223	A1228V	1228	Missense	distal	5	no	11.468	11.457	EPSD	COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P35568	IRS1	P27361	MAPK3	S1223	E1224Q	1224	Missense	proximal	1	no	11.468	12.772	EPSD	COSMIC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P35568	IRS1	P27361	MAPK3	S1223	L1226V	1226	Missense	distal	3	no	11.468	11.463	EPSD	COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P35568	IRS1	P27361	MAPK3	S1227	R1220C	1220	Missense	distal	-7	no	10.304	10.491	EPSD	COSMIC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P35568	IRS1	P27361	MAPK3	S1227	D1225Y	1225	Missense	proximal	-2	no	10.304	10.602	EPSD	COSMIC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P35568	IRS1	P27361	MAPK3	S1227	A1228V	1228	Missense	proximal	1	no	10.304	10.121	EPSD	COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P35568	IRS1	P27361	MAPK3	S1227	E1224Q	1224	Missense	distal	-3	no	10.304	10.278	EPSD	COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P35568	IRS1	P27361	MAPK3	S1227	L1226V	1226	Missense	proximal	-1	no	10.304	10.309	EPSD	COSMIC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P35568	IRS1	P27361	MAPK3	S1231	Q1235P	1235	Missense	distal	4	no	9.321	9.464	EPSD	COSMIC	9.358	Gain
CMGC_MAPK_ERK1_MAPK3_ST	P35568	IRS1	P27361	MAPK3	S1231	E1224Q	1224	Missense	distal	-7	no	9.321	9.371	EPSD	COSMIC	9.358	Gain
CMGC_MAPK_ERK1_MAPK3_ST	P46527	CDKN1B	P27361	MAPK3	S10	R5L	5	Missense	distal	-5	no	14.456	14.442	EPSD	COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P46527	CDKN1B	P27361	MAPK3	S10	E14K	14	Missense	distal	4	no	14.456	14.418	EPSD	COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P46527	CDKN1B	P27361	MAPK3	S10	M16T	16	Missense	distal	6	no	14.456	14.950	EPSD	COSMIC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P46527	CDKN1B	P27361	MAPK3	S10	N3D	3	Missense	distal	-7	no	14.456	14.432	EPSD	COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P46527	CDKN1B	P27361	MAPK3	S10	P11S	11	Missense	proximal	1	no	14.456	5.403	EPSD	COSMIC	9.358	Loss
CMGC_MAPK_ERK1_MAPK3_ST	P46527	CDKN1B	P27361	MAPK3	S10	S12N	12	Missense	proximal	2	no	14.456	14.439	EPSD	COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P46527	CDKN1B	P27361	MAPK3	S10	D17E	17	Missense	distal	7	no	14.456	14.454	EPSD	COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P46527	CDKN1B	P27361	MAPK3	S106	Q107R	107	Missense	proximal	1	no	9.902	8.345	EPSD	COSMIC	9.358	Loss
CMGC_MAPK_ERK1_MAPK3_ST	P46527	CDKN1B	P27361	MAPK3	S106	D108N	108	Missense	proximal	2	no	9.902	9.896	EPSD	COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P46527	CDKN1B	P27361	MAPK3	S175	R169K	169	Missense	distal	-6	no	10.278	10.280	EPSD	COSMIC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P46527	CDKN1B	P27361	MAPK3	S175	N168K	168	Missense	distal	-7	no	10.278	10.294	EPSD	COSMIC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P46527	CDKN1B	P27361	MAPK3	S175	G182D	182	Missense	distal	7	no	10.278	10.245	EPSD	COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P46527	CDKN1B	P27361	MAPK3	S178	V184L	184	Missense	distal	6	no	20.295	20.377	EPSD	COSMIC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P46527	CDKN1B	P27361	MAPK3	S178	G182D	182	Missense	distal	4	no	20.295	20.336	EPSD	COSMIC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P46527	CDKN1B	P27361	MAPK3	T187	V184L	184	Missense	distal	-3	no	17.172	17.169	PhosphoSitePlus	COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P46527	CDKN1B	P27361	MAPK3	T187	G182D	182	Missense	distal	-5	no	17.172	17.181	PhosphoSitePlus	COSMIC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P46527	CDKN1B	P27361	MAPK3	T187	R194K	194	Missense	distal	7	no	17.172	17.178	PhosphoSitePlus	COSMIC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q14934	NFATC4	P27361	MAPK3	S73	P75H	75	Missense	proximal	2	no	16.925	16.911	EPSD	COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q14934	NFATC4	P27361	MAPK3	S73	P66H	66	Missense	distal	-7	no	16.925	16.959	EPSD	COSMIC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q14934	NFATC4	P27361	MAPK3	S73	P66A	66	Missense	distal	-7	no	16.925	17.037	EPSD	COSMIC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q14934	NFATC4	P27361	MAPK3	S73	P69L	69	Missense	distal	-4	no	16.925	16.812	EPSD	COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q14934	NFATC4	P27361	MAPK3	S73	R77Q	77	Missense	distal	4	no	16.925	16.880	EPSD	COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q14934	NFATC4	P27361	MAPK3	S73	P78A	78	Missense	distal	5	no	16.925	16.713	EPSD	COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q14934	NFATC4	P27361	MAPK3	S73	S73L	73	Missense	central	0	yes	16.925	0.000	EPSD	COSMIC	9.358	Loss
CMGC_MAPK_ERK1_MAPK3_ST	Q14934	NFATC4	P27361	MAPK3	S122	P125H	125	Missense	distal	3	no	16.946	16.927	EPSD	COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q14934	NFATC4	P27361	MAPK3	S122	P128S	128	Missense	distal	6	no	16.946	17.076	EPSD	COSMIC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q14934	NFATC4	P27361	MAPK3	S122	S122C	122	Missense	central	0	yes	16.946	0.000	EPSD	COSMIC	9.358	Loss
CMGC_MAPK_ERK1_MAPK3_ST	Q14934	NFATC4	P27361	MAPK3	S122	S120Y	120	Missense	proximal	-2	no	16.946	16.713	EPSD	COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q14934	NFATC4	P27361	MAPK3	S122	P123S	123	Missense	proximal	1	no	16.946	7.892	EPSD	COSMIC	9.358	Loss
CMGC_MAPK_ERK1_MAPK3_ST	Q14934	NFATC4	P27361	MAPK3	S122	P125Q	125	Missense	distal	3	no	16.946	16.919	EPSD	COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q14934	NFATC4	P27361	MAPK3	S122	P127L	127	Missense	distal	5	no	16.946	16.718	EPSD	COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q14934	NFATC4	P27361	MAPK3	S122	T124M	124	Missense	proximal	2	no	16.946	16.913	EPSD	COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q14934	NFATC4	P27361	MAPK3	T124	P125H	125	Missense	proximal	1	no	15.979	8.223	EPSD	COSMIC	9.358	Loss
CMGC_MAPK_ERK1_MAPK3_ST	Q14934	NFATC4	P27361	MAPK3	T124	P128S	128	Missense	distal	4	no	15.979	16.028	EPSD	COSMIC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q14934	NFATC4	P27361	MAPK3	T124	S122C	122	Missense	proximal	-2	no	15.979	13.539	EPSD	COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q14934	NFATC4	P27361	MAPK3	T124	S120Y	120	Missense	distal	-4	no	15.979	15.876	EPSD	COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q14934	NFATC4	P27361	MAPK3	T124	P123S	123	Missense	proximal	-1	no	15.979	15.973	EPSD	COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q14934	NFATC4	P27361	MAPK3	T124	P125Q	125	Missense	proximal	1	no	15.979	8.035	EPSD	COSMIC	9.358	Loss
CMGC_MAPK_ERK1_MAPK3_ST	Q14934	NFATC4	P27361	MAPK3	T124	P127L	127	Missense	distal	3	no	15.979	15.942	EPSD	COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q14934	NFATC4	P27361	MAPK3	T124	A130V	130	Missense	distal	6	no	15.979	16.066	EPSD	COSMIC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q14934	NFATC4	P27361	MAPK3	T124	T124M	124	Missense	central	0	yes	15.979	0.000	EPSD	COSMIC	9.358	Loss
CMGC_MAPK_ERK1_MAPK3_ST	Q14934	NFATC4	P27361	MAPK3	S142	P148S	148	Missense	distal	6	no	17.252	17.381	EPSD	COSMIC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q14934	NFATC4	P27361	MAPK3	S142	G141W	141	Missense	proximal	-1	no	17.252	17.037	EPSD	COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q14934	NFATC4	P27361	MAPK3	S142	R144I	144	Missense	proximal	2	no	17.252	17.229	EPSD	COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q14934	NFATC4	P27361	MAPK3	S142	P149Q	149	Missense	distal	7	no	17.252	17.373	EPSD	COSMIC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q14934	NFATC4	P27361	MAPK3	S142	R144K	144	Missense	proximal	2	no	17.252	17.248	EPSD	COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q14934	NFATC4	P27361	MAPK3	S142	W138L	138	Missense	distal	-4	no	17.252	17.396	EPSD	COSMIC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q14934	NFATC4	P27361	MAPK3	S168	G163W	163	Missense	distal	-5	no	15.668	15.512	EPSD	COSMIC;GDSC;CCLE	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q14934	NFATC4	P27361	MAPK3	S168	S168N	168	Missense	central	0	yes	15.668	0.000	EPSD	COSMIC	9.358	Loss
CMGC_MAPK_ERK1_MAPK3_ST	Q14934	NFATC4	P27361	MAPK3	S168	G163R	163	Missense	distal	-5	no	15.668	15.666	EPSD	COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q14934	NFATC4	P27361	MAPK3	S168	G162V	162	Missense	distal	-6	no	15.668	15.401	EPSD	COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q14934	NFATC4	P27361	MAPK3	S170	G163W	163	Missense	distal	-7	no	17.114	17.405	EPSD	COSMIC;GDSC;CCLE	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q14934	NFATC4	P27361	MAPK3	S170	S168N	168	Missense	proximal	-2	no	17.114	16.170	EPSD	COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q14934	NFATC4	P27361	MAPK3	S170	G163R	163	Missense	distal	-7	no	17.114	17.159	EPSD	COSMIC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q14934	NFATC4	P27361	MAPK3	S213	R219I	219	Missense	distal	6	no	16.269	15.941	EPSD	COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q14934	NFATC4	P27361	MAPK3	S213	R208C	208	Missense	distal	-5	no	16.269	16.153	EPSD	COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q14934	NFATC4	P27361	MAPK3	S213	S217L	217	Missense	distal	4	no	16.269	16.066	EPSD	COSMIC;CCLE	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q14934	NFATC4	P27361	MAPK3	S213	R219Q	219	Missense	distal	6	no	16.269	16.200	EPSD	COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q14934	NFATC4	P27361	MAPK3	S213	S207F	207	Missense	distal	-6	no	16.269	15.802	EPSD	COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q14934	NFATC4	P27361	MAPK3	S213	P216L	216	Missense	distal	3	no	16.269	16.232	EPSD	COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q14934	NFATC4	P27361	MAPK3	S213	P214Q	214	Missense	proximal	1	no	16.269	8.325	EPSD	COSMIC	9.358	Loss
CMGC_MAPK_ERK1_MAPK3_ST	Q14934	NFATC4	P27361	MAPK3	S213	A206T	206	Missense	distal	-7	no	16.269	16.196	EPSD	COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q14934	NFATC4	P27361	MAPK3	S217	R219I	219	Missense	proximal	2	no	17.123	17.100	EPSD	COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q14934	NFATC4	P27361	MAPK3	S217	S217L	217	Missense	central	0	yes	17.123	0.000	EPSD	COSMIC;CCLE	9.358	Loss
CMGC_MAPK_ERK1_MAPK3_ST	Q14934	NFATC4	P27361	MAPK3	S217	R219Q	219	Missense	proximal	2	no	17.123	17.113	EPSD	COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q14934	NFATC4	P27361	MAPK3	S217	P216L	216	Missense	proximal	-1	no	17.123	17.028	EPSD	COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q14934	NFATC4	P27361	MAPK3	S217	P214Q	214	Missense	distal	-3	no	17.123	17.069	EPSD	COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q14934	NFATC4	P27361	MAPK3	S217	P224T	224	Missense	distal	7	no	17.123	17.164	EPSD	COSMIC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q14934	NFATC4	P27361	MAPK3	S217	R223W	223	Missense	distal	6	no	17.123	16.300	EPSD	COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q14934	NFATC4	P27361	MAPK3	S221	R219I	219	Missense	proximal	-2	no	14.393	13.955	EPSD	COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q14934	NFATC4	P27361	MAPK3	S221	P227Q	227	Missense	distal	6	no	14.393	14.212	EPSD	COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q14934	NFATC4	P27361	MAPK3	S221	P227H	227	Missense	distal	6	no	14.393	14.300	EPSD	COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q14934	NFATC4	P27361	MAPK3	S221	E228K	228	Missense	distal	7	no	14.393	14.464	EPSD	COSMIC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q14934	NFATC4	P27361	MAPK3	S221	S217L	217	Missense	distal	-4	no	14.393	14.253	EPSD	COSMIC;CCLE	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q14934	NFATC4	P27361	MAPK3	S221	R219Q	219	Missense	proximal	-2	no	14.393	14.029	EPSD	COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q14934	NFATC4	P27361	MAPK3	S221	P216L	216	Missense	distal	-5	no	14.393	14.339	EPSD	COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q14934	NFATC4	P27361	MAPK3	S221	P214Q	214	Missense	distal	-7	no	14.393	14.438	EPSD	COSMIC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q14934	NFATC4	P27361	MAPK3	S221	P224T	224	Missense	distal	3	no	14.393	14.375	EPSD	COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q14934	NFATC4	P27361	MAPK3	S221	R223W	223	Missense	proximal	2	no	14.393	14.333	EPSD	COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q14934	NFATC4	P27361	MAPK3	S221	T226S	226	Missense	distal	5	no	14.393	14.529	EPSD	COSMIC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q14934	NFATC4	P27361	MAPK3	T226	R219I	219	Missense	distal	-7	no	16.191	16.299	EPSD	COSMIC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q14934	NFATC4	P27361	MAPK3	T226	P227Q	227	Missense	proximal	1	no	16.191	8.247	EPSD	COSMIC	9.358	Loss
CMGC_MAPK_ERK1_MAPK3_ST	Q14934	NFATC4	P27361	MAPK3	T226	P227H	227	Missense	proximal	1	no	16.191	8.435	EPSD	COSMIC	9.358	Loss
CMGC_MAPK_ERK1_MAPK3_ST	Q14934	NFATC4	P27361	MAPK3	T226	E228K	228	Missense	proximal	2	no	16.191	16.183	EPSD	COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q14934	NFATC4	P27361	MAPK3	T226	R219Q	219	Missense	distal	-7	no	16.191	16.190	EPSD	COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q14934	NFATC4	P27361	MAPK3	T226	P224T	224	Missense	proximal	-2	no	16.191	15.205	EPSD	COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q14934	NFATC4	P27361	MAPK3	T226	R223W	223	Missense	distal	-3	no	16.191	16.023	EPSD	COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q14934	NFATC4	P27361	MAPK3	T226	W231S	231	Missense	distal	5	no	16.191	16.802	EPSD	COSMIC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q14934	NFATC4	P27361	MAPK3	S237	G235S	235	Missense	proximal	-2	no	16.625	17.665	EPSD	COSMIC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q14934	NFATC4	P27361	MAPK3	S237	R241L	241	Missense	distal	4	no	16.625	16.568	EPSD	COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q14934	NFATC4	P27361	MAPK3	S237	R241Q	241	Missense	distal	4	no	16.625	16.581	EPSD	COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q14934	NFATC4	P27361	MAPK3	S237	W231S	231	Missense	distal	-6	no	16.625	17.308	EPSD	COSMIC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q14934	NFATC4	P27361	MAPK3	T256	P257S	257	Missense	proximal	1	no	14.002	4.948	EPSD	COSMIC	9.358	Loss
CMGC_MAPK_ERK1_MAPK3_ST	Q14934	NFATC4	P27361	MAPK3	T256	R261W	261	Missense	distal	5	no	14.002	13.534	EPSD	COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q14934	NFATC4	P27361	MAPK3	T256	P253L	253	Missense	distal	-3	no	14.002	13.917	EPSD	COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q14934	NFATC4	P27361	MAPK3	T256	P260Q	260	Missense	distal	4	no	14.002	13.860	EPSD	COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q14934	NFATC4	P27361	MAPK3	T256	R261Q	261	Missense	distal	5	no	14.002	14.000	EPSD	COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q14934	NFATC4	P27361	MAPK3	T256	S259F	259	Missense	distal	3	no	14.002	13.937	EPSD	COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q14934	NFATC4	P27361	MAPK3	S259	P257S	257	Missense	proximal	-2	no	18.063	16.987	EPSD	COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q14934	NFATC4	P27361	MAPK3	S259	R261W	261	Missense	proximal	2	no	18.063	18.002	EPSD	COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q14934	NFATC4	P27361	MAPK3	S259	P253L	253	Missense	distal	-6	no	18.063	17.815	EPSD	COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q14934	NFATC4	P27361	MAPK3	S259	P260Q	260	Missense	proximal	1	no	18.063	10.119	EPSD	COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q14934	NFATC4	P27361	MAPK3	S259	R261Q	261	Missense	proximal	2	no	18.063	18.053	EPSD	COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q14934	NFATC4	P27361	MAPK3	S259	P265L	265	Missense	distal	6	no	18.063	17.836	EPSD	COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q14934	NFATC4	P27361	MAPK3	S259	S259F	259	Missense	central	0	yes	18.063	0.000	EPSD	COSMIC	9.358	Loss
CMGC_MAPK_ERK1_MAPK3_ST	Q14934	NFATC4	P27361	MAPK3	S264	P257S	257	Missense	distal	-7	no	17.258	17.220	EPSD	COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q14934	NFATC4	P27361	MAPK3	S264	R261W	261	Missense	distal	-3	no	17.258	17.091	EPSD	COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q14934	NFATC4	P27361	MAPK3	S264	P260Q	260	Missense	distal	-4	no	17.258	17.218	EPSD	COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q14934	NFATC4	P27361	MAPK3	S264	R261Q	261	Missense	distal	-3	no	17.258	17.250	EPSD	COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q14934	NFATC4	P27361	MAPK3	S264	P265L	265	Missense	proximal	1	no	17.258	8.220	EPSD	COSMIC	9.358	Loss
CMGC_MAPK_ERK1_MAPK3_ST	Q14934	NFATC4	P27361	MAPK3	S264	Y271H	271	Missense	distal	7	no	17.258	17.140	EPSD	COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q14934	NFATC4	P27361	MAPK3	S264	R269Q	269	Missense	distal	5	no	17.258	17.256	EPSD	COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q14934	NFATC4	P27361	MAPK3	S264	R269W	269	Missense	distal	5	no	17.258	16.790	EPSD	COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q14934	NFATC4	P27361	MAPK3	S264	R270H	270	Missense	distal	6	no	17.258	17.277	EPSD	COSMIC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q14934	NFATC4	P27361	MAPK3	S264	R270C	270	Missense	distal	6	no	17.258	16.632	EPSD	COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q14934	NFATC4	P27361	MAPK3	S264	S259F	259	Missense	distal	-5	no	17.258	17.124	EPSD	COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q14934	NFATC4	P27361	MAPK3	T276	P277Q	277	Missense	proximal	1	no	16.487	8.543	EPSD	COSMIC	9.358	Loss
CMGC_MAPK_ERK1_MAPK3_ST	Q14934	NFATC4	P27361	MAPK3	T276	S272F	272	Missense	distal	-4	no	16.487	16.298	EPSD	COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q14934	NFATC4	P27361	MAPK3	T276	G275S	275	Missense	proximal	-1	no	16.487	16.552	EPSD	COSMIC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q14934	NFATC4	P27361	MAPK3	T276	S273L	273	Missense	distal	-3	no	16.487	16.411	EPSD	COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q14934	NFATC4	P27361	MAPK3	T276	P282A	282	Missense	distal	6	no	16.487	16.091	EPSD	COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q14934	NFATC4	P27361	MAPK3	T276	Y271H	271	Missense	distal	-5	no	16.487	16.514	EPSD	COSMIC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q14934	NFATC4	P27361	MAPK3	T276	R269Q	269	Missense	distal	-7	no	16.487	16.486	EPSD	COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q14934	NFATC4	P27361	MAPK3	T276	S272P	272	Missense	distal	-4	no	16.487	16.459	EPSD	COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q14934	NFATC4	P27361	MAPK3	T276	R269W	269	Missense	distal	-7	no	16.487	16.732	EPSD	COSMIC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q14934	NFATC4	P27361	MAPK3	T276	S281F	281	Missense	distal	5	no	16.487	16.062	EPSD	COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q14934	NFATC4	P27361	MAPK3	T276	R270H	270	Missense	distal	-6	no	16.487	16.482	EPSD	COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q14934	NFATC4	P27361	MAPK3	T276	R270C	270	Missense	distal	-6	no	16.487	16.088	EPSD	COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q14934	NFATC4	P27361	MAPK3	T276	S274L	274	Missense	proximal	-2	no	16.487	16.178	EPSD	COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q14934	NFATC4	P27361	MAPK3	S281	R286W	286	Missense	distal	5	no	16.490	16.022	EPSD	COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q14934	NFATC4	P27361	MAPK3	S281	P277Q	277	Missense	distal	-4	no	16.490	16.450	EPSD	COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q14934	NFATC4	P27361	MAPK3	S281	S285P	285	Missense	distal	4	no	16.490	16.441	EPSD	COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q14934	NFATC4	P27361	MAPK3	S281	G275S	275	Missense	distal	-6	no	16.490	16.552	EPSD	COSMIC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q14934	NFATC4	P27361	MAPK3	S281	G288W	288	Missense	distal	7	no	16.490	17.096	EPSD	COSMIC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q14934	NFATC4	P27361	MAPK3	S281	P282A	282	Missense	proximal	1	no	16.490	7.250	EPSD	COSMIC	9.358	Loss
CMGC_MAPK_ERK1_MAPK3_ST	Q14934	NFATC4	P27361	MAPK3	S281	R286H	286	Missense	distal	5	no	16.490	16.525	EPSD	COSMIC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q14934	NFATC4	P27361	MAPK3	S281	R287H	287	Missense	distal	6	no	16.490	16.509	EPSD	COSMIC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q14934	NFATC4	P27361	MAPK3	S281	R287S	287	Missense	distal	6	no	16.490	16.731	EPSD	COSMIC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q14934	NFATC4	P27361	MAPK3	S281	S281F	281	Missense	central	0	yes	16.490	0.000	EPSD	COSMIC	9.358	Loss
CMGC_MAPK_ERK1_MAPK3_ST	Q14934	NFATC4	P27361	MAPK3	S281	S274L	274	Missense	distal	-7	no	16.490	16.634	EPSD	COSMIC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q14934	NFATC4	P27361	MAPK3	S311	P314S	314	Missense	distal	3	no	18.249	18.244	EPSD	COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q14934	NFATC4	P27361	MAPK3	S311	P312S	312	Missense	proximal	1	no	18.249	9.196	EPSD	COSMIC	9.358	Loss
CMGC_MAPK_ERK1_MAPK3_ST	Q14934	NFATC4	P27361	MAPK3	S311	P304L	304	Missense	distal	-7	no	18.249	18.356	EPSD	COSMIC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q14934	NFATC4	P27361	MAPK3	S311	D316Y	316	Missense	distal	5	no	18.249	18.075	EPSD	COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q14934	NFATC4	P27361	MAPK3	S311	F315L	315	Missense	distal	4	no	18.249	18.460	EPSD	COSMIC;CCLE	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q14934	NFATC4	P27361	MAPK3	S334	S335P	335	Missense	proximal	1	no	8.571	17.624	EPSD	COSMIC	9.358	Gain
CMGC_MAPK_ERK1_MAPK3_ST	Q14934	NFATC4	P27361	MAPK3	S382	D376N	376	Missense	distal	-6	no	15.232	15.170	EPSD	COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q14934	NFATC4	P27361	MAPK3	S382	V380A	380	Missense	proximal	-2	no	15.232	14.535	EPSD	COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q14934	NFATC4	P27361	MAPK3	S382	P383T	383	Missense	proximal	1	no	15.232	6.354	EPSD	COSMIC	9.358	Loss
CMGC_MAPK_ERK1_MAPK3_ST	Q14934	NFATC4	P27361	MAPK3	S382	S387F	387	Missense	distal	5	no	15.232	14.807	EPSD	COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q14934	NFATC4	P27361	MAPK3	S382	D376Y	376	Missense	distal	-6	no	15.232	15.039	EPSD	COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q14934	NFATC4	P27361	MAPK3	S395	P396T	396	Missense	proximal	1	no	13.646	4.769	EPSD	COSMIC	9.358	Loss
CMGC_MAPK_ERK1_MAPK3_ST	Q14934	NFATC4	P27361	MAPK3	S395	A402V	402	Missense	distal	7	no	13.646	13.619	EPSD	COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q14934	NFATC4	P27361	MAPK3	S395	R399K	399	Missense	distal	4	no	13.646	13.655	EPSD	COSMIC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q14934	NFATC4	P27361	MAPK3	S395	G392V	392	Missense	distal	-3	no	13.646	13.607	EPSD	COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q14934	NFATC4	P27361	MAPK3	S395	F398S	398	Missense	distal	3	no	13.646	13.711	EPSD	COSMIC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q14934	NFATC4	P27361	MAPK3	S395	I391T	391	Missense	distal	-4	no	13.646	13.748	EPSD	COSMIC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q14934	NFATC4	P27361	MAPK3	S395	S395I	395	Missense	central	0	yes	13.646	0.000	EPSD	COSMIC	9.358	Loss
CMGC_MAPK_ERK1_MAPK3_ST	Q14934	NFATC4	P27361	MAPK3	S592	E589K	589	Missense	distal	-3	no	14.486	14.455	EPSD	COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q14934	NFATC4	P27361	MAPK3	S592	S594L	594	Missense	proximal	2	no	14.486	14.462	EPSD	COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q14934	NFATC4	P27361	MAPK3	S592	P586H	586	Missense	distal	-6	no	14.486	14.406	EPSD	COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q14934	NFATC4	P27361	MAPK3	S592	P593S	593	Missense	proximal	1	no	14.486	5.432	EPSD	COSMIC	9.358	Loss
CMGC_MAPK_ERK1_MAPK3_ST	Q14934	NFATC4	P27361	MAPK3	S592	R599I	599	Missense	distal	7	no	14.486	14.715	EPSD	COSMIC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q14934	NFATC4	P27361	MAPK3	S592	S594R	594	Missense	proximal	2	no	14.486	14.473	EPSD	COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q14934	NFATC4	P27361	MAPK3	S676	P677A	677	Missense	proximal	1	no	15.164	5.925	PhosphoSitePlus	COSMIC	9.358	Loss
CMGC_MAPK_ERK1_MAPK3_ST	Q14934	NFATC4	P27361	MAPK3	S676	S676N	676	Missense	central	0	yes	15.164	0.000	PhosphoSitePlus	COSMIC	9.358	Loss
CMGC_MAPK_ERK1_MAPK3_ST	Q14934	NFATC4	P27361	MAPK3	S676	G671W	671	Missense	distal	-5	no	15.164	15.008	PhosphoSitePlus	COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q14934	NFATC4	P27361	MAPK3	S676	R675H	675	Missense	proximal	-1	no	15.164	15.167	PhosphoSitePlus	COSMIC;CCLE	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q14934	NFATC4	P27361	MAPK3	S676	R672W	672	Missense	distal	-4	no	15.164	14.957	PhosphoSitePlus	COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q14934	NFATC4	P27361	MAPK3	S676	S669A	669	Missense	distal	-7	no	15.164	15.314	PhosphoSitePlus	COSMIC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q14934	NFATC4	P27361	MAPK3	S676	G671R	671	Missense	distal	-5	no	15.164	15.162	PhosphoSitePlus	COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q14934	NFATC4	P27361	MAPK3	S676	F683C	683	Missense	distal	7	no	15.164	15.285	PhosphoSitePlus	COSMIC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q14934	NFATC4	P27361	MAPK3	S676	R675C	675	Missense	proximal	-1	no	15.164	14.979	PhosphoSitePlus	COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q14934	NFATC4	P27361	MAPK3	S716	P723L	723	Missense	distal	7	no	17.356	17.549	EPSD	COSMIC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q14934	NFATC4	P27361	MAPK3	S716	P721H	721	Missense	distal	5	no	17.356	17.291	EPSD	COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q14934	NFATC4	P27361	MAPK3	S716	F709C	709	Missense	distal	-7	no	17.356	17.407	EPSD	COSMIC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q14934	NFATC4	P27361	MAPK3	S716	R719K	719	Missense	distal	3	no	17.356	17.354	EPSD	COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q14934	NFATC4	P27361	MAPK3	S716	P723S	723	Missense	distal	7	no	17.356	17.279	EPSD	COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q14934	NFATC4	P27361	MAPK3	S819	G824C	824	Missense	distal	5	no	18.092	17.633	EPSD	COSMIC;CCLE	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q14934	NFATC4	P27361	MAPK3	S819	P817S	817	Missense	proximal	-2	no	18.092	17.016	EPSD	COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q14934	NFATC4	P27361	MAPK3	S819	P820A	820	Missense	proximal	1	no	18.092	8.852	EPSD	COSMIC	9.358	Loss
CMGC_MAPK_ERK1_MAPK3_ST	Q14934	NFATC4	P27361	MAPK3	S819	S819F	819	Missense	central	0	yes	18.092	0.000	EPSD	COSMIC	9.358	Loss
CMGC_MAPK_ERK1_MAPK3_ST	Q14934	NFATC4	P27361	MAPK3	S819	A818V	818	Missense	proximal	-1	no	18.092	18.141	EPSD	COSMIC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q14934	NFATC4	P27361	MAPK3	S819	A818S	818	Missense	proximal	-1	no	18.092	18.225	EPSD	COSMIC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q14934	NFATC4	P27361	MAPK3	S819	P825S	825	Missense	distal	6	no	18.092	18.221	EPSD	COSMIC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q14934	NFATC4	P27361	MAPK3	S819	P815H	815	Missense	distal	-4	no	18.092	18.056	EPSD	COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q14934	NFATC4	P27361	MAPK3	S819	P813S	813	Missense	distal	-6	no	18.092	18.176	EPSD	COSMIC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q14934	NFATC4	P27361	MAPK3	S819	E823A	823	Missense	distal	4	no	18.092	17.861	EPSD	COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q14934	NFATC4	P27361	MAPK3	S819	R812W	812	Missense	distal	-7	no	18.092	18.338	EPSD	COSMIC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q14934	NFATC4	P27361	MAPK3	S819	F826Y	826	Missense	distal	7	no	18.092	17.856	EPSD	COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q14934	NFATC4	P27361	MAPK3	S819	P815S	815	Missense	distal	-4	no	18.092	18.119	EPSD	COSMIC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P02686	MBP	P27361	MAPK3	S19	A12S	12	Missense	distal	-7	no	9.539	9.389	EPSD	COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P02686	MBP	P27361	MAPK3	S26	K28N	28	Missense	proximal	2	no	9.387	9.386	EPSD	COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P02686	MBP	P27361	MAPK3	T106	D104N	104	Missense	proximal	-2	no	9.764	9.350	EPSD	COSMIC	9.358	Loss
CMGC_MAPK_ERK1_MAPK3_ST	P02686	MBP	P27361	MAPK3	T106	P100S	100	Missense	distal	-6	no	9.764	9.848	EPSD	COSMIC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P02686	MBP	P27361	MAPK3	T229	T229M	229	Missense	central	0	yes	15.084	0.000	EPSD	COSMIC	9.358	Loss
CMGC_MAPK_ERK1_MAPK3_ST	P02686	MBP	P27361	MAPK3	T229	P235S	235	Missense	distal	6	no	15.084	15.214	EPSD	COSMIC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P02686	MBP	P27361	MAPK3	T229	R231C	231	Missense	proximal	2	no	15.084	15.035	EPSD	COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P02686	MBP	P27361	MAPK3	T229	S236L	236	Missense	distal	7	no	15.084	15.354	EPSD	COSMIC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P02686	MBP	P27361	MAPK3	T232	T229M	229	Missense	distal	-3	no	15.869	15.772	PhosphoSitePlus	COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P02686	MBP	P27361	MAPK3	T232	G238E	238	Missense	distal	6	no	15.869	15.970	PhosphoSitePlus	COSMIC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P02686	MBP	P27361	MAPK3	T232	P235S	235	Missense	distal	3	no	15.869	15.865	PhosphoSitePlus	COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P02686	MBP	P27361	MAPK3	T232	R231C	231	Missense	proximal	-1	no	15.869	15.684	PhosphoSitePlus	COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P02686	MBP	P27361	MAPK3	T232	S236L	236	Missense	distal	4	no	15.869	15.666	PhosphoSitePlus	COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P02686	MBP	P27361	MAPK3	S285	K286E	286	Missense	proximal	1	no	1.912	9.817	EPSD	COSMIC	9.358	Gain
CMGC_MAPK_ERK1_MAPK3_ST	P02686	MBP	P27361	MAPK3	S295	S295G	295	Missense	central	0	yes	10.143	0.000	EPSD	COSMIC	9.358	Loss
CMGC_MAPK_ERK1_MAPK3_ST	P02686	MBP	P27361	MAPK3	S295	R296P	296	Missense	proximal	1	no	10.143	19.644	EPSD	COSMIC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P02686	MBP	P27361	MAPK3	S295	R296C	296	Missense	proximal	1	no	10.143	4.336	EPSD	COSMIC	9.358	Loss
CMGC_MAPK_ERK1_MAPK3_ST	P02686	MBP	P27361	MAPK3	S295	K289M	289	Missense	distal	-6	no	10.143	9.880	EPSD	COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P02686	MBP	P27361	MAPK3	S299	S295G	295	Missense	distal	-4	no	18.653	18.614	EPSD	COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P02686	MBP	P27361	MAPK3	S299	R296P	296	Missense	distal	-3	no	18.653	18.699	EPSD	COSMIC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P02686	MBP	P27361	MAPK3	S299	R296C	296	Missense	distal	-3	no	18.653	18.512	EPSD	COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q9UPT5	EXOC7	P27361	MAPK3	S130	P134Q	134	Missense	distal	4	no	16.918	16.776	EPSD	COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q9UPT5	EXOC7	P27361	MAPK3	S250	G246V	246	Missense	distal	-4	no	18.233	18.119	PhosphoSitePlus	COSMIC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q9UPT5	EXOC7	P27361	MAPK3	T260	K258N	258	Missense	proximal	-2	no	14.904	15.224	EPSD	COSMIC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q9UPT5	EXOC7	P27361	MAPK3	T260	V266I	266	Missense	distal	6	no	14.904	14.773	EPSD	COSMIC	9.358	Down-regulation
TKL_RIPK_RIPK3_ST	Q9UER7	DAXX	Q9Y572	RIPK3	S33	A31V	31	Missense	proximal	-2	no	27.419	25.018	EPSD	COSMIC	23.118	Down-regulation
TKL_RIPK_RIPK3_ST	Q9UER7	DAXX	Q9Y572	RIPK3	S110	R115C	115	Missense	distal	5	no	27.214	26.881	EPSD	COSMIC	23.118	Down-regulation
TKL_RIPK_RIPK3_ST	Q9UER7	DAXX	Q9Y572	RIPK3	S110	A103G	103	Missense	distal	-7	no	27.214	27.217	EPSD	COSMIC	23.118	Up-regulation
TKL_RIPK_RIPK3_ST	Q9UER7	DAXX	Q9Y572	RIPK3	S110	S114C	114	Missense	distal	4	no	27.214	28.247	EPSD	COSMIC	23.118	Up-regulation
TKL_RIPK_RIPK3_ST	Q9UER7	DAXX	Q9Y572	RIPK3	S110	A103S	103	Missense	distal	-7	no	27.214	28.564	EPSD	COSMIC	23.118	Up-regulation
TKL_RIPK_RIPK3_ST	Q9UER7	DAXX	Q9Y572	RIPK3	S110	R115W	115	Missense	distal	5	no	27.214	26.944	EPSD	COSMIC	23.118	Down-regulation
TKL_RIPK_RIPK3_ST	Q9UER7	DAXX	Q9Y572	RIPK3	T181	R185C	185	Missense	distal	4	no	25.707	25.115	EPSD	COSMIC	23.118	Down-regulation
TKL_RIPK_RIPK3_ST	Q9UER7	DAXX	Q9Y572	RIPK3	T181	Q177E	177	Missense	distal	-4	no	25.707	25.722	EPSD	COSMIC	23.118	Up-regulation
TKL_RIPK_RIPK3_ST	Q9UER7	DAXX	Q9Y572	RIPK3	S561	F567S	567	Missense	distal	6	no	22.855	24.420	EPSD	COSMIC	23.118	Gain
TKL_RIPK_RIPK3_ST	Q9UER7	DAXX	Q9Y572	RIPK3	S561	E559K	559	Missense	proximal	-2	no	22.855	24.026	EPSD	COSMIC	23.118	Gain
TKL_RIPK_RIPK3_ST	Q9UER7	DAXX	Q9Y572	RIPK3	T584	S589F	589	Missense	distal	5	no	24.391	25.231	EPSD	COSMIC	23.118	Up-regulation
TKL_RIPK_RIPK3_ST	Q9UER7	DAXX	Q9Y572	RIPK3	T584	S581F	581	Missense	distal	-3	no	24.391	22.306	EPSD	COSMIC	23.118	Loss
TKL_RIPK_RIPK3_ST	Q9UER7	DAXX	Q9Y572	RIPK3	T584	D577Y	577	Missense	distal	-7	no	24.391	25.187	EPSD	COSMIC;GDSC;CCLE	23.118	Up-regulation
TKL_RIPK_RIPK3_ST	Q9UER7	DAXX	Q9Y572	RIPK3	T584	T584M	584	Missense	central	0	yes	24.391	0.000	EPSD	COSMIC	23.118	Loss
TKL_RIPK_RIPK3_ST	Q9UER7	DAXX	Q9Y572	RIPK3	T584	S581C	581	Missense	distal	-3	no	24.391	22.575	EPSD	COSMIC	23.118	Loss
TKL_RIPK_RIPK3_ST	Q9UER7	DAXX	Q9Y572	RIPK3	S625	P628S	628	Missense	distal	3	no	20.948	32.557	EPSD	COSMIC	23.118	Gain
TKL_RIPK_RIPK3_ST	Q9UER7	DAXX	Q9Y572	RIPK3	S632	P628S	628	Missense	distal	-4	no	28.632	28.316	EPSD	COSMIC	23.118	Down-regulation
TKL_RIPK_RIPK3_ST	Q9UER7	DAXX	Q9Y572	RIPK3	S632	P627L	627	Missense	distal	-5	no	28.632	29.091	EPSD	COSMIC	23.118	Up-regulation
TKL_RIPK_RIPK3_ST	Q9UER7	DAXX	Q9Y572	RIPK3	S632	P627S	627	Missense	distal	-5	no	28.632	29.704	EPSD	COSMIC	23.118	Up-regulation
TKL_RIPK_RIPK3_ST	Q9UER7	DAXX	Q9Y572	RIPK3	S632	E635Q	635	Missense	distal	3	no	28.632	28.860	EPSD	COSMIC	23.118	Up-regulation
TKL_RIPK_RIPK3_ST	Q9UER7	DAXX	Q9Y572	RIPK3	S632	S632F	632	Missense	central	0	yes	28.632	0.000	EPSD	COSMIC	23.118	Loss
TKL_RIPK_RIPK3_ST	Q9UER7	DAXX	Q9Y572	RIPK3	T639	E635Q	635	Missense	distal	-4	no	25.590	25.575	EPSD	COSMIC	23.118	Down-regulation
TKL_RIPK_RIPK3_ST	Q9UER7	DAXX	Q9Y572	RIPK3	T639	P643S	643	Missense	distal	4	no	25.590	23.757	EPSD	COSMIC	23.118	Down-regulation
TKL_RIPK_RIPK3_ST	Q9UER7	DAXX	Q9Y572	RIPK3	T639	S632F	632	Missense	distal	-7	no	25.590	24.553	EPSD	COSMIC	23.118	Down-regulation
TKL_RIPK_RIPK3_ST	Q9UER7	DAXX	Q9Y572	RIPK3	S668	S675F	675	Missense	distal	7	no	51.604	50.176	PhosphoSitePlus	COSMIC	23.118	Down-regulation
TKL_RIPK_RIPK3_ST	Q9UER7	DAXX	Q9Y572	RIPK3	S668	C664R	664	Missense	distal	-4	no	51.604	51.607	PhosphoSitePlus	COSMIC	23.118	Up-regulation
TKL_RIPK_RIPK3_ST	Q9UER7	DAXX	Q9Y572	RIPK3	S668	S668C	668	Missense	central	0	yes	51.604	0.000	PhosphoSitePlus	COSMIC	23.118	Loss
TKL_RIPK_RIPK3_ST	Q9UER7	DAXX	Q9Y572	RIPK3	S668	S668N	668	Missense	central	0	yes	51.604	0.000	PhosphoSitePlus	COSMIC	23.118	Loss
TKL_RIPK_RIPK3_ST	Q9UER7	DAXX	Q9Y572	RIPK3	S668	T665I	665	Missense	distal	-3	no	51.604	51.516	PhosphoSitePlus	COSMIC	23.118	Down-regulation
TKL_RIPK_RIPK3_ST	Q9UER7	DAXX	Q9Y572	RIPK3	S690	S688C	688	Missense	proximal	-2	no	26.081	22.425	EPSD	COSMIC	23.118	Loss
TKL_RIPK_RIPK3_ST	Q9UER7	DAXX	Q9Y572	RIPK3	T695	C699Y	699	Missense	distal	4	no	23.693	22.578	EPSD	COSMIC	23.118	Loss
TKL_RIPK_RIPK3_ST	Q9UER7	DAXX	Q9Y572	RIPK3	T695	L698F	698	Missense	distal	3	no	23.693	24.953	EPSD	COSMIC	23.118	Up-regulation
TKL_RIPK_RIPK3_ST	Q9UER7	DAXX	Q9Y572	RIPK3	T695	S688C	688	Missense	distal	-7	no	23.693	22.282	EPSD	COSMIC	23.118	Loss
TKL_RIPK_RIPK3_ST	Q9UER7	DAXX	Q9Y572	RIPK3	T709	R705W	705	Missense	distal	-4	no	31.362	31.344	EPSD	COSMIC;GDSC;CCLE	23.118	Down-regulation
TKL_RIPK_RIPK3_ST	Q9UER7	DAXX	Q9Y572	RIPK3	T709	H711Y	711	Missense	proximal	2	no	31.362	31.194	EPSD	COSMIC	23.118	Down-regulation
TKL_RIPK_RIPK3_ST	Q9UER7	DAXX	Q9Y572	RIPK3	T709	R705L	705	Missense	distal	-4	no	31.362	31.384	EPSD	COSMIC	23.118	Up-regulation
TKL_RIPK_RIPK3_ST	Q9UER7	DAXX	Q9Y572	RIPK3	T709	P703S	703	Missense	distal	-6	no	31.362	31.961	EPSD	COSMIC	23.118	Up-regulation
TKL_RIPK_RIPK3_ST	Q9UER7	DAXX	Q9Y572	RIPK3	S739	D738V	738	Missense	proximal	-1	no	27.218	27.112	EPSD	COSMIC	23.118	Down-regulation
TKL_RIPK_RIPK3_ST	Q9Y572	RIPK3	Q9Y572	RIPK3	S199	S199P	199	Missense	central	0	yes	55.827	0.000	EPSD	COSMIC	23.118	Loss
TKL_RIPK_RIPK3_ST	Q9Y572	RIPK3	Q9Y572	RIPK3	S199	V194E	194	Missense	distal	-5	no	55.827	55.713	EPSD	COSMIC	23.118	Down-regulation
TKL_RIPK_RIPK3_ST	Q9Y572	RIPK3	Q9Y572	RIPK3	S199	R196Q	196	Missense	distal	-3	no	55.827	56.187	EPSD	COSMIC	23.118	Up-regulation
TKL_RIPK_RIPK3_ST	Q9Y572	RIPK3	Q9Y572	RIPK3	T333	R340H	340	Missense	distal	7	no	25.511	25.101	EPSD	COSMIC	23.118	Down-regulation
TKL_RIPK_RIPK3_ST	Q9Y572	RIPK3	Q9Y572	RIPK3	T333	I334V	334	Missense	proximal	1	no	25.511	26.463	EPSD	COSMIC	23.118	Up-regulation
TKL_RIPK_RIPK3_ST	Q9Y572	RIPK3	Q9Y572	RIPK3	S339	R340H	340	Missense	proximal	1	no	26.917	26.848	EPSD	COSMIC	23.118	Down-regulation
TKL_RIPK_RIPK3_ST	Q9Y572	RIPK3	Q9Y572	RIPK3	S339	I334V	334	Missense	distal	-5	no	26.917	26.473	EPSD	COSMIC	23.118	Down-regulation
TKL_RIPK_RIPK3_ST	Q9Y572	RIPK3	Q9Y572	RIPK3	T416	P421A	421	Missense	distal	5	no	25.166	24.658	EPSD	COSMIC	23.118	Down-regulation
TKL_RIPK_RIPK3_ST	Q9Y572	RIPK3	Q9Y572	RIPK3	T416	S418R	418	Missense	proximal	2	no	25.166	25.470	EPSD	COSMIC	23.118	Up-regulation
TKL_RIPK_RIPK3_ST	Q9Y572	RIPK3	Q9Y572	RIPK3	T416	P419S	419	Missense	distal	3	no	25.166	36.775	EPSD	COSMIC	23.118	Up-regulation
TKL_RIPK_RIPK3_ST	Q8NB16	MLKL	Q9Y572	RIPK3	T357	E351Q	351	Missense	distal	-6	no	44.609	44.845	PhosphoSitePlus;EPSD	COSMIC	23.118	Up-regulation
TKL_RIPK_RIPK3_ST	Q8NB16	MLKL	Q9Y572	RIPK3	T357	Q356R	356	Missense	proximal	-1	no	44.609	45.163	PhosphoSitePlus;EPSD	COSMIC	23.118	Up-regulation
TKL_RIPK_RIPK3_ST	Q8NB16	MLKL	Q9Y572	RIPK3	T357	T364M	364	Missense	distal	7	no	44.609	44.356	PhosphoSitePlus;EPSD	COSMIC	23.118	Down-regulation
TKL_RIPK_RIPK3_ST	Q8NB16	MLKL	Q9Y572	RIPK3	T357	T364K	364	Missense	distal	7	no	44.609	45.022	PhosphoSitePlus;EPSD	COSMIC	23.118	Up-regulation
TKL_RIPK_RIPK3_ST	Q8NB16	MLKL	Q9Y572	RIPK3	S358	E351Q	351	Missense	distal	-7	no	47.147	47.151	EPSD;PhosphoSitePlus	COSMIC	23.118	Up-regulation
TKL_RIPK_RIPK3_ST	Q8NB16	MLKL	Q9Y572	RIPK3	S358	Q356R	356	Missense	proximal	-2	no	47.147	44.415	EPSD;PhosphoSitePlus	COSMIC	23.118	Down-regulation
TKL_RIPK_RIPK3_ST	Q8NB16	MLKL	Q9Y572	RIPK3	S358	T364M	364	Missense	distal	6	no	47.147	46.021	EPSD;PhosphoSitePlus	COSMIC	23.118	Down-regulation
TKL_RIPK_RIPK3_ST	Q8NB16	MLKL	Q9Y572	RIPK3	S358	T364K	364	Missense	distal	6	no	47.147	46.916	EPSD;PhosphoSitePlus	COSMIC	23.118	Down-regulation
TKL_RIPK_RIPK3_ST	P09622	DLD	Q9Y572	RIPK3	T135	H140N	140	Missense	distal	5	no	42.289	42.151	PhosphoSitePlus	COSMIC	23.118	Down-regulation
TKL_RIPK_RIPK3_ST	P09622	DLD	Q9Y572	RIPK3	T135	A139T	139	Missense	distal	4	no	42.289	41.948	PhosphoSitePlus	COSMIC	23.118	Down-regulation
TKL_RIPK_RIPK3_ST	P09622	DLD	Q9Y572	RIPK3	S230	L228F	228	Missense	proximal	-2	no	25.363	26.023	EPSD	COSMIC	23.118	Up-regulation
TKL_RIPK_RIPK3_ST	P09622	DLD	Q9Y572	RIPK3	S230	I224V	224	Missense	distal	-6	no	25.363	25.313	EPSD	COSMIC	23.118	Down-regulation
TKL_RIPK_RIPK3_ST	P09622	DLD	Q9Y572	RIPK3	S230	G236C	236	Missense	distal	6	no	25.363	27.440	EPSD	COSMIC	23.118	Up-regulation
TKL_RIPK_RIPK3_ST	P09622	DLD	Q9Y572	RIPK3	S230	G229K	229	Missense	proximal	-1	no	25.363	24.104	EPSD	COSMIC	23.118	Down-regulation
TKL_RIPK_RIPK3_ST	P09622	DLD	Q9Y572	RIPK3	T276	F272C	272	Missense	distal	-4	no	25.073	25.169	EPSD	COSMIC	23.118	Up-regulation
TKL_RIPK_RIPK3_ST	P09622	DLD	Q9Y572	RIPK3	T276	G280E	280	Missense	distal	4	no	25.073	23.989	EPSD	COSMIC	23.118	Down-regulation
STE_STE20_KHS_MAP4K1_ST	Q16584	MAP3K11	Q92918	MAP4K1	T277	A283T	283	Missense	distal	6	no	2.492	2.396	EPSD	COSMIC	2.024	Down-regulation
STE_STE20_KHS_MAP4K1_ST	Q16584	MAP3K11	Q92918	MAP4K1	T277	R272W	272	Missense	distal	-5	no	2.492	2.649	EPSD	COSMIC	2.024	Up-regulation
STE_STE20_KHS_MAP4K1_ST	Q16584	MAP3K11	Q92918	MAP4K1	T277	R272P	272	Missense	distal	-5	no	2.492	2.538	EPSD	COSMIC	2.024	Up-regulation
STE_STE20_KHS_MAP4K1_ST	Q16584	MAP3K11	Q92918	MAP4K1	T277	R272Q	272	Missense	distal	-5	no	2.492	2.596	EPSD	COSMIC	2.024	Up-regulation
STE_STE20_KHS_MAP4K1_ST	Q16584	MAP3K11	Q92918	MAP4K1	S281	A283T	283	Missense	proximal	2	no	7.980	7.620	PhosphoSitePlus	COSMIC	2.024	Down-regulation
STE_STE20_KHS_MAP4K1_ST	Q16584	MAP3K11	Q92918	MAP4K1	T526	G520W	520	Missense	distal	-6	no	4.012	4.222	EPSD	COSMIC	2.024	Up-regulation
STE_STE20_KHS_MAP4K1_ST	Q16584	MAP3K11	Q92918	MAP4K1	T526	P521S	521	Missense	distal	-5	no	4.012	3.909	EPSD	COSMIC	2.024	Down-regulation
STE_STE20_KHS_MAP4K1_ST	Q16584	MAP3K11	Q92918	MAP4K1	T677	P683S	683	Missense	distal	6	no	0.441	2.082	EPSD	COSMIC	2.024	Gain
STE_STE20_KHS_MAP4K1_ST	Q16584	MAP3K11	Q92918	MAP4K1	S693	P691H	691	Missense	proximal	-2	no	2.901	2.893	EPSD	COSMIC	2.024	Down-regulation
STE_STE20_KHS_MAP4K1_ST	Q16584	MAP3K11	Q92918	MAP4K1	S693	I696F	696	Missense	distal	3	no	2.901	2.980	EPSD	COSMIC	2.024	Up-regulation
STE_STE20_KHS_MAP4K1_ST	Q16584	MAP3K11	Q92918	MAP4K1	S746	P750S	750	Missense	distal	4	no	2.845	2.799	EPSD	COSMIC	2.024	Down-regulation
STE_STE20_KHS_MAP4K1_ST	Q16584	MAP3K11	Q92918	MAP4K1	S774	L772F	772	Missense	proximal	-2	no	3.104	3.121	EPSD	COSMIC	2.024	Up-regulation
STE_STE20_KHS_MAP4K1_ST	Q16584	MAP3K11	Q92918	MAP4K1	S774	R773H	773	Missense	proximal	-1	no	3.104	2.835	EPSD	COSMIC	2.024	Down-regulation
STE_STE20_KHS_MAP4K1_ST	Q9BXL7	CARD11	Q92918	MAP4K1	S212	K215M	215	Missense	distal	3	no	2.422	2.508	EPSD	COSMIC	2.024	Up-regulation
STE_STE20_KHS_MAP4K1_ST	Q9BXL7	CARD11	Q92918	MAP4K1	S212	A205V	205	Missense	distal	-7	no	2.422	2.261	EPSD	COSMIC	2.024	Down-regulation
STE_STE20_KHS_MAP4K1_ST	Q9BXL7	CARD11	Q92918	MAP4K1	S212	A209S	209	Missense	distal	-3	no	2.422	2.612	EPSD	COSMIC;GDSC;CCLE	2.024	Up-regulation
STE_STE20_KHS_MAP4K1_ST	Q9BXL7	CARD11	Q92918	MAP4K1	S212	M217L	217	Missense	distal	5	no	2.422	2.354	EPSD	COSMIC	2.024	Down-regulation
STE_STE20_KHS_MAP4K1_ST	Q9BXL7	CARD11	Q92918	MAP4K1	S212	E214D	214	Missense	proximal	2	no	2.422	2.108	EPSD	COSMIC	2.024	Down-regulation
STE_STE20_KHS_MAP4K1_ST	Q9BXL7	CARD11	Q92918	MAP4K1	S212	E213K	213	Missense	proximal	1	no	2.422	2.551	EPSD	COSMIC	2.024	Up-regulation
STE_STE20_KHS_MAP4K1_ST	Q9BXL7	CARD11	Q92918	MAP4K1	S433	E432K	432	Missense	proximal	-1	no	2.160	2.545	EPSD	COSMIC	2.024	Up-regulation
STE_STE20_KHS_MAP4K1_ST	Q9BXL7	CARD11	Q92918	MAP4K1	S433	A426V	426	Missense	distal	-7	no	2.160	2.000	EPSD	COSMIC	2.024	Loss
STE_STE20_KHS_MAP4K1_ST	Q9BXL7	CARD11	Q92918	MAP4K1	S433	R436W	436	Missense	distal	3	no	2.160	2.166	EPSD	COSMIC	2.024	Up-regulation
STE_STE20_KHS_MAP4K1_ST	Q9BXL7	CARD11	Q92918	MAP4K1	S433	R437C	437	Missense	distal	4	no	2.160	1.802	EPSD	COSMIC	2.024	Loss
STE_STE20_KHS_MAP4K1_ST	Q9BXL7	CARD11	Q92918	MAP4K1	S433	R436Q	436	Missense	distal	3	no	2.160	2.030	EPSD	COSMIC;GDSC;CCLE	2.024	Down-regulation
STE_STE20_KHS_MAP4K1_ST	Q9BXL7	CARD11	Q92918	MAP4K1	S433	A426T	426	Missense	distal	-7	no	2.160	2.028	EPSD	COSMIC	2.024	Down-regulation
STE_STE20_KHS_MAP4K1_ST	Q9BXL7	CARD11	Q92918	MAP4K1	S433	S439F	439	Missense	distal	6	no	2.160	0.580	EPSD	COSMIC	2.024	Loss
STE_STE20_KHS_MAP4K1_ST	Q9BXL7	CARD11	Q92918	MAP4K1	T532	H527N	527	Missense	distal	-5	no	2.288	2.334	EPSD	COSMIC;GDSC;CCLE	2.024	Up-regulation
STE_STE20_KHS_MAP4K1_ST	Q9BXL7	CARD11	Q92918	MAP4K1	T532	S538F	538	Missense	distal	6	no	2.288	0.708	EPSD	COSMIC	2.024	Loss
STE_STE20_KHS_MAP4K1_ST	Q9BXL7	CARD11	Q92918	MAP4K1	T532	K525R	525	Missense	distal	-7	no	2.288	2.181	EPSD	COSMIC	2.024	Down-regulation
STE_STE20_KHS_MAP4K1_ST	Q9BXL7	CARD11	Q92918	MAP4K1	T532	T532M	532	Missense	central	0	yes	2.288	0.000	EPSD	COSMIC;GDSC	2.024	Loss
STE_STE20_KHS_MAP4K1_ST	Q9BXL7	CARD11	Q92918	MAP4K1	T532	H527R	527	Missense	distal	-5	no	2.288	2.129	EPSD	COSMIC	2.024	Down-regulation
STE_STE20_KHS_MAP4K1_ST	Q9BXL7	CARD11	Q92918	MAP4K1	T532	E530D	530	Missense	proximal	-2	no	2.288	2.133	EPSD	COSMIC;GDSC	2.024	Down-regulation
STE_STE20_KHS_MAP4K1_ST	Q9BXL7	CARD11	Q92918	MAP4K1	S535	S538F	538	Missense	distal	3	no	3.463	3.523	EPSD	COSMIC	2.024	Up-regulation
STE_STE20_KHS_MAP4K1_ST	Q9BXL7	CARD11	Q92918	MAP4K1	S535	G540E	540	Missense	distal	5	no	3.463	3.486	EPSD	COSMIC	2.024	Up-regulation
STE_STE20_KHS_MAP4K1_ST	Q9BXL7	CARD11	Q92918	MAP4K1	S535	G540R	540	Missense	distal	5	no	3.463	3.530	EPSD	COSMIC;GDSC	2.024	Up-regulation
STE_STE20_KHS_MAP4K1_ST	Q9BXL7	CARD11	Q92918	MAP4K1	S535	T532M	532	Missense	distal	-3	no	3.463	3.382	EPSD	COSMIC;GDSC	2.024	Down-regulation
STE_STE20_KHS_MAP4K1_ST	Q9BXL7	CARD11	Q92918	MAP4K1	S535	E530D	530	Missense	distal	-5	no	3.463	3.523	EPSD	COSMIC;GDSC	2.024	Up-regulation
STE_STE20_KHS_MAP4K1_ST	Q9BXL7	CARD11	Q92918	MAP4K1	S556	K550N	550	Missense	distal	-6	no	7.521	7.678	PhosphoSitePlus;EPSD	COSMIC	2.024	Up-regulation
STE_STE20_KHS_MAP4K1_ST	Q9BXL7	CARD11	Q92918	MAP4K1	S556	R557S	557	Missense	proximal	1	no	7.521	7.364	PhosphoSitePlus;EPSD	COSMIC	2.024	Down-regulation
STE_STE20_KHS_MAP4K1_ST	Q9BXL7	CARD11	Q92918	MAP4K1	S556	P554S	554	Missense	proximal	-2	no	7.521	7.625	PhosphoSitePlus;EPSD	COSMIC	2.024	Up-regulation
STE_STE20_KHS_MAP4K1_ST	Q9BXL7	CARD11	Q92918	MAP4K1	S556	P553T	553	Missense	distal	-3	no	7.521	7.558	PhosphoSitePlus;EPSD	COSMIC	2.024	Up-regulation
STE_STE20_KHS_MAP4K1_ST	Q9BXL7	CARD11	Q92918	MAP4K1	S556	S559C	559	Missense	distal	3	no	7.521	7.466	PhosphoSitePlus;EPSD	COSMIC	2.024	Down-regulation
STE_STE20_KHS_MAP4K1_ST	Q9BXL7	CARD11	Q92918	MAP4K1	S558	R557S	557	Missense	proximal	-1	no	8.222	8.354	EPSD;PhosphoSitePlus	COSMIC	2.024	Up-regulation
STE_STE20_KHS_MAP4K1_ST	Q9BXL7	CARD11	Q92918	MAP4K1	S558	P554S	554	Missense	distal	-4	no	8.222	7.881	EPSD;PhosphoSitePlus	COSMIC	2.024	Down-regulation
STE_STE20_KHS_MAP4K1_ST	Q9BXL7	CARD11	Q92918	MAP4K1	S558	A565V	565	Missense	distal	7	no	8.222	8.226	EPSD;PhosphoSitePlus	COSMIC	2.024	Up-regulation
STE_STE20_KHS_MAP4K1_ST	Q9BXL7	CARD11	Q92918	MAP4K1	S558	P553T	553	Missense	distal	-5	no	8.222	8.338	EPSD;PhosphoSitePlus	COSMIC	2.024	Up-regulation
STE_STE20_KHS_MAP4K1_ST	Q9BXL7	CARD11	Q92918	MAP4K1	S558	A565T	565	Missense	distal	7	no	8.222	8.212	EPSD;PhosphoSitePlus	COSMIC	2.024	Down-regulation
STE_STE20_KHS_MAP4K1_ST	Q9BXL7	CARD11	Q92918	MAP4K1	S558	S559C	559	Missense	proximal	1	no	8.222	8.168	EPSD;PhosphoSitePlus	COSMIC	2.024	Down-regulation
STE_STE20_KHS_MAP4K1_ST	Q9BXL7	CARD11	Q92918	MAP4K1	T564	R557S	557	Missense	distal	-7	no	3.729	4.064	EPSD	COSMIC	2.024	Up-regulation
STE_STE20_KHS_MAP4K1_ST	Q9BXL7	CARD11	Q92918	MAP4K1	T564	G569E	569	Missense	distal	5	no	3.729	3.753	EPSD	COSMIC	2.024	Up-regulation
STE_STE20_KHS_MAP4K1_ST	Q9BXL7	CARD11	Q92918	MAP4K1	T564	A565V	565	Missense	proximal	1	no	3.729	3.491	EPSD	COSMIC	2.024	Down-regulation
STE_STE20_KHS_MAP4K1_ST	Q9BXL7	CARD11	Q92918	MAP4K1	T564	E566K	566	Missense	proximal	2	no	3.729	3.633	EPSD	COSMIC	2.024	Down-regulation
STE_STE20_KHS_MAP4K1_ST	Q9BXL7	CARD11	Q92918	MAP4K1	T564	P568Q	568	Missense	distal	4	no	3.729	3.493	EPSD	COSMIC	2.024	Down-regulation
STE_STE20_KHS_MAP4K1_ST	Q9BXL7	CARD11	Q92918	MAP4K1	T564	P567S	567	Missense	distal	3	no	3.729	3.733	EPSD	COSMIC	2.024	Up-regulation
STE_STE20_KHS_MAP4K1_ST	Q9BXL7	CARD11	Q92918	MAP4K1	T564	A565T	565	Missense	proximal	1	no	3.729	3.548	EPSD	COSMIC	2.024	Down-regulation
STE_STE20_KHS_MAP4K1_ST	Q9BXL7	CARD11	Q92918	MAP4K1	T564	S559C	559	Missense	distal	-5	no	3.729	3.906	EPSD	COSMIC	2.024	Up-regulation
STE_STE20_KHS_MAP4K1_ST	Q9BXL7	CARD11	Q92918	MAP4K1	T564	D571N	571	Missense	distal	7	no	3.729	3.727	EPSD	COSMIC	2.024	Down-regulation
STE_STE20_KHS_MAP4K1_ST	Q9BXL7	CARD11	Q92918	MAP4K1	S615	S618C	618	Missense	distal	3	no	2.675	2.620	EPSD	COSMIC	2.024	Down-regulation
STE_STE20_KHS_MAP4K1_ST	Q9BXL7	CARD11	Q92918	MAP4K1	S615	S618F	618	Missense	distal	3	no	2.675	2.736	EPSD	COSMIC	2.024	Up-regulation
STE_STE20_KHS_MAP4K1_ST	Q9BXL7	CARD11	Q92918	MAP4K1	S615	S615F	615	Missense	central	0	yes	2.675	0.000	EPSD	COSMIC	2.024	Loss
STE_STE20_KHS_MAP4K1_ST	Q9BXL7	CARD11	Q92918	MAP4K1	S615	S622H	622	Missense	distal	7	no	2.675	2.667	EPSD	COSMIC	2.024	Down-regulation
STE_STE20_KHS_MAP4K1_ST	Q9BXL7	CARD11	Q92918	MAP4K1	S615	S622F	622	Missense	distal	7	no	2.675	2.660	EPSD	COSMIC	2.024	Down-regulation
STE_STE20_KHS_MAP4K1_ST	Q9BXL7	CARD11	Q92918	MAP4K1	S615	P613L	613	Missense	proximal	-2	no	2.675	2.471	EPSD	COSMIC	2.024	Down-regulation
STE_STE20_KHS_MAP4K1_ST	Q9BXL7	CARD11	Q92918	MAP4K1	S615	R608C	608	Missense	distal	-7	no	2.675	2.799	EPSD	COSMIC	2.024	Up-regulation
STE_STE20_KHS_MAP4K1_ST	Q9BXL7	CARD11	Q92918	MAP4K1	S615	S622C	622	Missense	distal	7	no	2.675	2.664	EPSD	COSMIC	2.024	Down-regulation
STE_STE20_KHS_MAP4K1_ST	Q9BXL7	CARD11	Q92918	MAP4K1	S615	S618A	618	Missense	distal	3	no	2.675	2.332	EPSD	COSMIC;CCLE	2.024	Down-regulation
STE_STE20_KHS_MAP4K1_ST	Q9BXL7	CARD11	Q92918	MAP4K1	S615	S619F	619	Missense	distal	4	no	2.675	2.740	EPSD	COSMIC	2.024	Up-regulation
STE_STE20_KHS_MAP4K1_ST	Q9BXL7	CARD11	Q92918	MAP4K1	S615	H617Y	617	Missense	proximal	2	no	2.675	2.680	EPSD	COSMIC	2.024	Up-regulation
STE_STE20_KHS_MAP4K1_ST	Q9BXL7	CARD11	Q92918	MAP4K1	S615	S615P	615	Missense	central	0	yes	2.675	0.000	EPSD	COSMIC	2.024	Loss
STE_STE20_KHS_MAP4K1_ST	Q9BXL7	CARD11	Q92918	MAP4K1	S625	Y631C	631	Missense	distal	6	no	1.676	2.137	EPSD	COSMIC	2.024	Gain
STE_STE20_KHS_MAP4K1_ST	Q9BXL7	CARD11	Q92918	MAP4K1	S652	T654I	654	Missense	proximal	2	no	3.120	3.148	EPSD	COSMIC	2.024	Up-regulation
STE_STE20_KHS_MAP4K1_ST	Q9BXL7	CARD11	Q92918	MAP4K1	S652	L645P	645	Missense	distal	-7	no	3.120	2.981	EPSD	COSMIC	2.024	Down-regulation
STE_STE20_KHS_MAP4K1_ST	Q9BXL7	CARD11	Q92918	MAP4K1	S652	L645Q	645	Missense	distal	-7	no	3.120	3.073	EPSD	COSMIC	2.024	Down-regulation
STE_STE20_KHS_MAP4K1_ST	Q9BXL7	CARD11	Q92918	MAP4K1	S652	F649S	649	Missense	distal	-3	no	3.120	3.083	EPSD	COSMIC	2.024	Down-regulation
STE_STE20_KHS_MAP4K1_ST	Q9BXL7	CARD11	Q92918	MAP4K1	S652	R647S	647	Missense	distal	-5	no	3.120	3.063	EPSD	COSMIC	2.024	Down-regulation
STE_STE20_KHS_MAP4K1_ST	Q9BXL7	CARD11	Q92918	MAP4K1	T864	R866Q	866	Missense	proximal	2	no	2.650	2.773	EPSD	COSMIC	2.024	Up-regulation
STE_STE20_KHS_MAP4K1_ST	Q9BXL7	CARD11	Q92918	MAP4K1	T864	L868F	868	Missense	distal	4	no	2.650	2.768	EPSD	COSMIC	2.024	Up-regulation
STE_STE20_KHS_MAP4K1_ST	Q9BXL7	CARD11	Q92918	MAP4K1	T864	T861A	861	Missense	distal	-3	no	2.650	2.472	EPSD	COSMIC	2.024	Down-regulation
STE_STE20_KHS_MAP4K1_ST	Q9BXL7	CARD11	Q92918	MAP4K1	T864	T864A	864	Missense	central	0	yes	2.650	0.000	EPSD	COSMIC	2.024	Loss
STE_STE20_KHS_MAP4K1_ST	Q9BXL7	CARD11	Q92918	MAP4K1	T864	R869Q	869	Missense	distal	5	no	2.650	2.604	EPSD	COSMIC	2.024	Down-regulation
STE_STE20_KHS_MAP4K1_ST	Q9BXL7	CARD11	Q92918	MAP4K1	T864	T861I	861	Missense	distal	-3	no	2.650	2.697	EPSD	COSMIC	2.024	Up-regulation
STE_STE20_KHS_MAP4K1_ST	Q9BXL7	CARD11	Q92918	MAP4K1	T880	S879L	879	Missense	proximal	-1	no	2.799	2.616	EPSD	COSMIC	2.024	Down-regulation
STE_STE20_KHS_MAP4K1_ST	Q9BXL7	CARD11	Q92918	MAP4K1	T880	L878F	878	Missense	proximal	-2	no	2.799	2.816	EPSD	COSMIC	2.024	Up-regulation
STE_STE20_KHS_MAP4K1_ST	Q9BXL7	CARD11	Q92918	MAP4K1	T880	V885I	885	Missense	distal	5	no	2.799	2.761	EPSD	COSMIC	2.024	Down-regulation
STE_STE20_KHS_MAP4K1_ST	Q9BXL7	CARD11	Q92918	MAP4K1	T880	R884L	884	Missense	distal	4	no	2.799	2.490	EPSD	COSMIC	2.024	Down-regulation
STE_STE20_KHS_MAP4K1_ST	Q9BXL7	CARD11	Q92918	MAP4K1	S923	P926S	926	Missense	distal	3	no	2.838	2.842	EPSD	COSMIC	2.024	Up-regulation
STE_STE20_KHS_MAP4K1_ST	Q9BXL7	CARD11	Q92918	MAP4K1	S923	S929R	929	Missense	distal	6	no	2.838	0.899	EPSD	COSMIC	2.024	Loss
STE_STE20_KHS_MAP4K1_ST	Q9BXL7	CARD11	Q92918	MAP4K1	S923	R920C	920	Missense	distal	-3	no	2.838	2.770	EPSD	COSMIC	2.024	Down-regulation
STE_STE20_KHS_MAP4K1_ST	Q9BXL7	CARD11	Q92918	MAP4K1	S923	S925N	925	Missense	proximal	2	no	2.838	2.321	EPSD	COSMIC	2.024	Down-regulation
STE_STE20_KHS_MAP4K1_ST	Q9BXL7	CARD11	Q92918	MAP4K1	S923	R918Q	918	Missense	distal	-5	no	2.838	2.942	EPSD	COSMIC	2.024	Up-regulation
STE_STE20_KHS_MAP4K1_ST	Q9BXL7	CARD11	Q92918	MAP4K1	T1020	Q1018H	1018	Missense	proximal	-2	no	2.283	2.188	EPSD	COSMIC	2.024	Down-regulation
STE_STE20_KHS_MAP4K1_ST	Q9BXL7	CARD11	Q92918	MAP4K1	T1020	E1021K	1021	Missense	proximal	1	no	2.283	2.412	EPSD	COSMIC	2.024	Up-regulation
STE_STE20_KHS_MAP4K1_ST	Q9BXL7	CARD11	Q92918	MAP4K1	T1020	R1016K	1016	Missense	distal	-4	no	2.283	2.434	EPSD	COSMIC	2.024	Up-regulation
STE_STE20_KHS_MAP4K1_ST	Q9BXL7	CARD11	Q92918	MAP4K1	T1020	R1017K	1017	Missense	distal	-3	no	2.283	2.195	EPSD	COSMIC	2.024	Down-regulation
STE_STE20_KHS_MAP4K1_ST	Q9BXL7	CARD11	Q92918	MAP4K1	T1020	I1024T	1024	Missense	distal	4	no	2.283	2.110	EPSD	COSMIC	2.024	Down-regulation
STE_STE20_KHS_MAP4K1_ST	Q9BXL7	CARD11	Q92918	MAP4K1	T1020	L1015F	1015	Missense	distal	-5	no	2.283	2.362	EPSD	COSMIC	2.024	Up-regulation
STE_STE20_KHS_MAP4K1_ST	Q9BXL7	CARD11	Q92918	MAP4K1	T1020	E1013K	1013	Missense	distal	-7	no	2.283	2.319	EPSD	COSMIC	2.024	Up-regulation
STE_STE20_KHS_MAP4K1_ST	Q92918	MAP4K1	Q92918	MAP4K1	T165	A160D	160	Missense	distal	-5	no	9.210	9.375	PhosphoSitePlus	COSMIC	2.024	Up-regulation
STE_STE20_KHS_MAP4K1_ST	Q92918	MAP4K1	Q92918	MAP4K1	S320	R316W	316	Missense	distal	-4	no	2.186	2.222	EPSD	COSMIC	2.024	Up-regulation
STE_STE20_KHS_MAP4K1_ST	Q92918	MAP4K1	Q92918	MAP4K1	S320	R317W	317	Missense	distal	-3	no	2.186	2.137	EPSD	COSMIC	2.024	Down-regulation
STE_STE20_KHS_MAP4K1_ST	Q92918	MAP4K1	Q92918	MAP4K1	S320	R317Q	317	Missense	distal	-3	no	2.186	2.082	EPSD	COSMIC	2.024	Down-regulation
STE_STE20_KHS_MAP4K1_ST	Q92918	MAP4K1	Q92918	MAP4K1	S320	P315S	315	Missense	distal	-5	no	2.186	2.084	EPSD	COSMIC	2.024	Down-regulation
STE_STE20_KHS_MAP4K1_ST	Q92918	MAP4K1	Q92918	MAP4K1	S320	R323L	323	Missense	distal	3	no	2.186	2.128	EPSD	COSMIC	2.024	Down-regulation
STE_STE20_KHS_MAP4K1_ST	Q92918	MAP4K1	Q92918	MAP4K1	S320	R319L	319	Missense	proximal	-1	no	2.186	2.134	EPSD	COSMIC	2.024	Down-regulation
STE_STE20_KHS_MAP4K1_ST	Q92918	MAP4K1	Q92918	MAP4K1	S407	D408G	408	Missense	proximal	1	no	2.828	2.814	EPSD	COSMIC	2.024	Down-regulation
STE_STE20_KHS_MAP4K1_ST	Q92918	MAP4K1	Q92918	MAP4K1	S407	G410S	410	Missense	distal	3	no	2.828	2.869	EPSD	COSMIC	2.024	Up-regulation
STE_STE20_KHS_MAP4K1_ST	Q92918	MAP4K1	Q92918	MAP4K1	T445	H449Y	449	Missense	distal	4	no	2.333	2.508	EPSD	COSMIC	2.024	Up-regulation
STE_STE20_KHS_MAP4K1_ST	Q92918	MAP4K1	Q92918	MAP4K1	T445	G440R	440	Missense	distal	-5	no	2.333	2.221	EPSD	COSMIC	2.024	Down-regulation
STE_STE20_KHS_MAP4K1_ST	Q92918	MAP4K1	Q92918	MAP4K1	S447	H449Y	449	Missense	proximal	2	no	2.900	2.905	EPSD	COSMIC	2.024	Up-regulation
STE_STE20_KHS_MAP4K1_ST	Q92918	MAP4K1	Q92918	MAP4K1	S447	G440R	440	Missense	distal	-7	no	2.900	2.905	EPSD	COSMIC	2.024	Up-regulation
STE_STE20_KHS_MAP4K1_ST	Q92918	MAP4K1	Q92918	MAP4K1	T451	H449Y	449	Missense	proximal	-2	no	3.361	3.197	EPSD	COSMIC	2.024	Down-regulation
STE_STE20_KHS_MAP4K1_ST	Q92918	MAP4K1	Q92918	MAP4K1	S463	D467H	467	Missense	distal	4	no	2.243	2.284	EPSD	COSMIC;GDSC;CCLE	2.024	Up-regulation
STE_STE20_KHS_MAP4K1_ST	Q92918	MAP4K1	Q92918	MAP4K1	S797	R793H	793	Missense	distal	-4	no	3.366	3.519	EPSD	COSMIC	2.024	Up-regulation
STE_STE20_KHS_MAP4K1_ST	Q92918	MAP4K1	Q92918	MAP4K1	S797	R793C	793	Missense	distal	-4	no	3.366	3.465	EPSD	COSMIC	2.024	Up-regulation
STE_STE20_KHS_MAP4K1_ST	Q92918	MAP4K1	Q92918	MAP4K1	S797	S797P	797	Missense	central	0	yes	3.366	0.000	EPSD	COSMIC	2.024	Loss
STE_STE20_KHS_MAP4K1_ST	Q13094	LCP2	Q92918	MAP4K1	S106	D112N	112	Missense	distal	6	no	1.597	2.527	EPSD	COSMIC;GDSC;CCLE	2.024	Gain
STE_STE20_KHS_MAP4K1_ST	Q13094	LCP2	Q92918	MAP4K1	S246	D251N	251	Missense	distal	5	no	2.359	2.301	EPSD	COSMIC	2.024	Down-regulation
STE_STE20_KHS_MAP4K1_ST	Q13094	LCP2	Q92918	MAP4K1	S246	L243I	243	Missense	distal	-3	no	2.359	2.452	EPSD	COSMIC	2.024	Up-regulation
STE_STE20_KHS_MAP4K1_ST	Q13094	LCP2	Q92918	MAP4K1	S246	D244H	244	Missense	proximal	-2	no	2.359	2.471	EPSD	COSMIC	2.024	Up-regulation
STE_STE20_KHS_MAP4K1_ST	Q13094	LCP2	Q92918	MAP4K1	S297	R293S	293	Missense	distal	-4	no	3.146	3.280	EPSD	COSMIC	2.024	Up-regulation
STE_STE20_KHS_MAP4K1_ST	Q13094	LCP2	Q92918	MAP4K1	S344	S338N	338	Missense	distal	-6	no	2.268	2.117	EPSD	COSMIC;GDSC;CCLE	2.024	Down-regulation
STE_STE20_KHS_MAP4K1_ST	Q13094	LCP2	Q92918	MAP4K1	S369	S376F	376	Missense	distal	7	no	4.461	4.445	EPSD	COSMIC	2.024	Down-regulation
STE_STE20_KHS_MAP4K1_ST	Q13094	LCP2	Q92918	MAP4K1	S369	P372S	372	Missense	distal	3	no	4.461	4.464	EPSD	COSMIC	2.024	Up-regulation
STE_STE20_KHS_MAP4K1_ST	Q13094	LCP2	Q92918	MAP4K1	S369	A363T	363	Missense	distal	-6	no	4.461	4.426	EPSD	COSMIC	2.024	Down-regulation
STE_STE20_KHS_MAP4K1_ST	Q13094	LCP2	Q92918	MAP4K1	S376	S376F	376	Missense	central	0	yes	9.054	0.000	PhosphoSitePlus	COSMIC	2.024	Loss
STE_STE20_KHS_MAP4K1_ST	Q13094	LCP2	Q92918	MAP4K1	S376	P372S	372	Missense	distal	-4	no	9.054	8.713	PhosphoSitePlus	COSMIC	2.024	Down-regulation
TK_Eph_EPHB2_Y	P10301	RRAS	P29323	EPHB2	Y66	C70R	70	Missense	distal	4	no	0.830	0.829	PhosphoSitePlus	COSMIC	0.394	Down-regulation
TK_Eph_EPHB2_Y	P10301	RRAS	P29323	EPHB2	Y66	E63D	63	Missense	distal	-3	no	0.830	0.815	PhosphoSitePlus	COSMIC	0.394	Down-regulation
Other_CAMKK_CAMKK-Meta_CAMKK1_ST	Q16566	CAMK4	Q8N5S9	CAMKK1	S12	S10P	10	Missense	proximal	-2	no	2.421	2.342	EPSD;PhosphoSitePlus	COSMIC	1.176	Down-regulation
Other_CAMKK_CAMKK-Meta_CAMKK1_ST	Q16566	CAMK4	Q8N5S9	CAMKK1	S12	S15Y	15	Missense	distal	3	no	2.421	2.426	EPSD;PhosphoSitePlus	COSMIC	1.176	Up-regulation
Other_CAMKK_CAMKK-Meta_CAMKK1_ST	Q16566	CAMK4	Q8N5S9	CAMKK1	S13	S10P	10	Missense	distal	-3	no	2.064	1.967	EPSD;PhosphoSitePlus	COSMIC	1.176	Down-regulation
Other_CAMKK_CAMKK-Meta_CAMKK1_ST	Q16566	CAMK4	Q8N5S9	CAMKK1	S13	S15Y	15	Missense	proximal	2	no	2.064	2.130	EPSD;PhosphoSitePlus	COSMIC	1.176	Up-regulation
Other_CAMKK_CAMKK-Meta_CAMKK1_ST	Q16566	CAMK4	Q8N5S9	CAMKK1	T204	P210H	210	Missense	distal	6	no	3.913	3.914	EPSD	COSMIC	1.176	Up-regulation
Other_CAMKK_CAMKK-Meta_CAMKK1_ST	Q8TDC3	BRSK1	Q8N5S9	CAMKK1	T189	S190N	190	Missense	proximal	1	no	4.887	4.870	EPSD	COSMIC	1.176	Down-regulation
Other_CAMKK_CAMKK-Meta_CAMKK1_ST	Q8TDC3	BRSK1	Q8N5S9	CAMKK1	T189	P194L	194	Missense	distal	5	no	4.887	4.868	EPSD	COSMIC	1.176	Down-regulation
Other_CAMKK_CAMKK-Meta_CAMKK1_ST	Q8TDC3	BRSK1	Q8N5S9	CAMKK1	T189	G183E	183	Missense	distal	-6	no	4.887	4.920	EPSD	COSMIC	1.176	Up-regulation
Other_CAMKK_CAMKK-Meta_CAMKK1_ST	Q8TDC3	BRSK1	Q8N5S9	CAMKK1	T406	S413F	413	Missense	distal	7	no	1.986	1.942	EPSD	COSMIC	1.176	Down-regulation
Other_CAMKK_CAMKK-Meta_CAMKK1_ST	Q8TDC3	BRSK1	Q8N5S9	CAMKK1	T406	G410R	410	Missense	distal	4	no	1.986	2.019	EPSD	COSMIC	1.176	Up-regulation
Other_CAMKK_CAMKK-Meta_CAMKK1_ST	Q8TDC3	BRSK1	Q8N5S9	CAMKK1	T406	S404C	404	Missense	proximal	-2	no	1.986	2.013	EPSD	COSMIC	1.176	Up-regulation
Other_CAMKK_CAMKK-Meta_CAMKK1_ST	Q8TDC3	BRSK1	Q8N5S9	CAMKK1	T406	S399F	399	Missense	distal	-7	no	1.986	1.949	EPSD	COSMIC	1.176	Down-regulation
Other_CAMKK_CAMKK-Meta_CAMKK1_ST	Q8TDC3	BRSK1	Q8N5S9	CAMKK1	T438	V433I	433	Missense	distal	-5	no	1.116	1.178	EPSD	COSMIC	1.176	Gain
Other_CAMKK_CAMKK-Meta_CAMKK1_ST	Q8TDC3	BRSK1	Q8N5S9	CAMKK1	S499	P506S	506	Missense	distal	7	no	1.631	1.738	EPSD	COSMIC	1.176	Up-regulation
Other_CAMKK_CAMKK-Meta_CAMKK1_ST	Q8TDC3	BRSK1	Q8N5S9	CAMKK1	S499	P493Q	493	Missense	distal	-6	no	1.631	1.666	EPSD	COSMIC	1.176	Up-regulation
Other_CAMKK_CAMKK-Meta_CAMKK1_ST	Q8TDC3	BRSK1	Q8N5S9	CAMKK1	S499	P493L	493	Missense	distal	-6	no	1.631	1.663	EPSD	COSMIC	1.176	Up-regulation
Other_CAMKK_CAMKK-Meta_CAMKK1_ST	Q8TDC3	BRSK1	Q8N5S9	CAMKK1	S512	P509L	509	Missense	distal	-3	no	0.977	1.284	EPSD	COSMIC	1.176	Gain
Other_CAMKK_CAMKK-Meta_CAMKK1_ST	Q8TDC3	BRSK1	Q8N5S9	CAMKK1	S527	P528L	528	Missense	proximal	1	no	1.843	1.812	EPSD	COSMIC	1.176	Down-regulation
Other_CAMKK_CAMKK-Meta_CAMKK1_ST	Q8TDC3	BRSK1	Q8N5S9	CAMKK1	S527	R525W	525	Missense	proximal	-2	no	1.843	1.854	EPSD	COSMIC	1.176	Up-regulation
Other_CAMKK_CAMKK-Meta_CAMKK1_ST	Q8TDC3	BRSK1	Q8N5S9	CAMKK1	S527	T523M	523	Missense	distal	-4	no	1.843	1.686	EPSD	COSMIC	1.176	Down-regulation
Other_CAMKK_CAMKK-Meta_CAMKK1_ST	Q8TDC3	BRSK1	Q8N5S9	CAMKK1	S527	G530R	530	Missense	distal	3	no	1.843	1.788	EPSD	COSMIC	1.176	Down-regulation
Other_CAMKK_CAMKK-Meta_CAMKK1_ST	Q8TDC3	BRSK1	Q8N5S9	CAMKK1	S676	R678C	678	Missense	proximal	2	no	0.996	1.470	EPSD	COSMIC	1.176	Gain
Other_CAMKK_CAMKK-Meta_CAMKK1_ST	Q13131	PRKAA1	Q8N5S9	CAMKK1	T244	N249H	249	Missense	distal	5	no	1.490	1.494	EPSD	COSMIC	1.176	Up-regulation
Other_CAMKK_CAMKK-Meta_CAMKK1_ST	Q13131	PRKAA1	Q8N5S9	CAMKK1	T244	P250H	250	Missense	distal	6	no	1.490	1.492	EPSD	COSMIC	1.176	Up-regulation
Other_CAMKK_CAMKK-Meta_CAMKK1_ST	Q13131	PRKAA1	Q8N5S9	CAMKK1	T244	L248F	248	Missense	distal	4	no	1.490	1.447	EPSD	COSMIC	1.176	Down-regulation
Other_CAMKK_CAMKK-Meta_CAMKK1_ST	Q13131	PRKAA1	Q8N5S9	CAMKK1	T490	V497A	497	Missense	distal	7	no	1.195	1.236	EPSD	COSMIC	1.176	Up-regulation
Other_CAMKK_CAMKK-Meta_CAMKK1_ST	Q13131	PRKAA1	Q8N5S9	CAMKK1	T490	A484D	484	Missense	distal	-6	no	1.195	1.163	EPSD	COSMIC	1.176	Loss
Other_CAMKK_CAMKK-Meta_CAMKK1_ST	Q13131	PRKAA1	Q8N5S9	CAMKK1	S498	V497A	497	Missense	proximal	-1	no	1.198	1.207	EPSD	COSMIC	1.176	Up-regulation
Other_CAMKK_CAMKK-Meta_CAMKK1_ST	Q13131	PRKAA1	Q8N5S9	CAMKK1	S498	R501G	501	Missense	distal	3	no	1.198	1.252	EPSD	COSMIC	1.176	Up-regulation
Other_CAMKK_CAMKK-Meta_CAMKK1_ST	Q13131	PRKAA1	Q8N5S9	CAMKK1	S498	R505K	505	Missense	distal	7	no	1.198	1.204	EPSD	COSMIC	1.176	Up-regulation
Other_CAMKK_CAMKK-Meta_CAMKK1_ST	Q13131	PRKAA1	Q8N5S9	CAMKK1	S498	R505G	505	Missense	distal	7	no	1.198	1.226	EPSD	COSMIC	1.176	Up-regulation
Other_CAMKK_CAMKK-Meta_CAMKK1_ST	Q13131	PRKAA1	Q8N5S9	CAMKK1	T522	S524F	524	Missense	proximal	2	no	1.486	1.542	EPSD	COSMIC	1.176	Up-regulation
Other_CAMKK_CAMKK-Meta_CAMKK1_ST	Q13131	PRKAA1	Q8N5S9	CAMKK1	S524	S524F	524	Missense	central	0	yes	1.448	0.000	EPSD	COSMIC	1.176	Loss
Other_CAMKK_CAMKK-Meta_CAMKK1_ST	Q13131	PRKAA1	Q8N5S9	CAMKK1	S524	S531F	531	Missense	distal	7	no	1.448	1.404	EPSD	COSMIC	1.176	Down-regulation
Other_CAMKK_CAMKK-Meta_CAMKK1_ST	Q13131	PRKAA1	Q8N5S9	CAMKK1	S527	S524F	524	Missense	distal	-3	no	2.750	2.814	EPSD	COSMIC	1.176	Up-regulation
Other_CAMKK_CAMKK-Meta_CAMKK1_ST	Q13131	PRKAA1	Q8N5S9	CAMKK1	S527	S531F	531	Missense	distal	4	no	2.750	2.578	EPSD	COSMIC	1.176	Down-regulation
Other_CAMKK_CAMKK-Meta_CAMKK1_ST	Q8IU85	CAMK1D	Q8N5S9	CAMKK1	S179	V177L	177	Missense	proximal	-2	no	1.759	1.717	EPSD	COSMIC	1.176	Down-regulation
Other_CAMKK_CAMKK-Meta_CAMKK1_ST	Q8IU85	CAMK1D	Q8N5S9	CAMKK1	T180	V177L	177	Missense	distal	-3	no	4.531	4.525	PhosphoSitePlus	COSMIC	1.176	Down-regulation
Other_CAMKK_CAMKK-Meta_CAMKK1_ST	Q8IU85	CAMK1D	Q8N5S9	CAMKK1	T184	V177L	177	Missense	distal	-7	no	1.972	1.921	EPSD	COSMIC	1.176	Down-regulation
Other_CAMKK_CAMKK-Meta_CAMKK1_ST	Q8IU85	CAMK1D	Q8N5S9	CAMKK1	S327	S330N	330	Missense	distal	3	no	1.519	1.511	EPSD	COSMIC	1.176	Down-regulation
Other_CAMKK_CAMKK-Meta_CAMKK1_ST	Q8IU85	CAMK1D	Q8N5S9	CAMKK1	S327	S326R	326	Missense	proximal	-1	no	1.519	1.529	EPSD	COSMIC	1.176	Up-regulation
Other_CAMKK_CAMKK-Meta_CAMKK1_ST	Q8IU85	CAMK1D	Q8N5S9	CAMKK1	S327	L322V	322	Missense	distal	-5	no	1.519	1.516	EPSD	COSMIC	1.176	Down-regulation
Other_CAMKK_CAMKK-Meta_CAMKK1_ST	Q14012	CAMK1	Q8N5S9	CAMKK1	S176	P171L	171	Missense	distal	-5	no	2.101	1.892	EPSD	COSMIC	1.176	Down-regulation
Other_CAMKK_CAMKK-Meta_CAMKK1_ST	Q14012	CAMK1	Q8N5S9	CAMKK1	T177	P171L	171	Missense	distal	-6	no	4.909	4.941	PhosphoSitePlus	COSMIC	1.176	Up-regulation
CK1_CK1_CK1-D_CSNK1D_ST	O15055	PER2	P48730	CSNK1D	S24	P18L	18	Missense	distal	-6	no	11.707	12.655	EPSD	COSMIC	11.915	Gain
CK1_CK1_CK1-D_CSNK1D_ST	O15055	PER2	P48730	CSNK1D	S24	P27Q	27	Missense	distal	3	no	11.707	13.026	EPSD	COSMIC	11.915	Gain
CK1_CK1_CK1-D_CSNK1D_ST	O15055	PER2	P48730	CSNK1D	S24	P21T	21	Missense	distal	-3	no	11.707	14.024	EPSD	COSMIC	11.915	Gain
CK1_CK1_CK1-D_CSNK1D_ST	O15055	PER2	P48730	CSNK1D	S56	D52G	52	Missense	distal	-4	no	12.088	12.040	EPSD	COSMIC	11.915	Down-regulation
CK1_CK1_CK1-D_CSNK1D_ST	O15055	PER2	P48730	CSNK1D	S56	S53L	53	Missense	distal	-3	no	12.088	9.884	EPSD	COSMIC	11.915	Loss
CK1_CK1_CK1-D_CSNK1D_ST	O15055	PER2	P48730	CSNK1D	S82	A86T	86	Missense	distal	4	no	14.216	14.663	EPSD	COSMIC	11.915	Up-regulation
CK1_CK1_CK1-D_CSNK1D_ST	O15055	PER2	P48730	CSNK1D	S662	S665P	665	Missense	distal	3	no	13.333	10.565	PhosphoSitePlus;EPSD	COSMIC;GDSC;CCLE	11.915	Loss
CK1_CK1_CK1-D_CSNK1D_ST	O15055	PER2	P48730	CSNK1D	S662	S665L	665	Missense	distal	3	no	13.333	11.545	PhosphoSitePlus;EPSD	COSMIC;GDSC;CCLE	11.915	Loss
CK1_CK1_CK1-D_CSNK1D_ST	O15055	PER2	P48730	CSNK1D	S662	P657L	657	Missense	distal	-5	no	13.333	11.700	PhosphoSitePlus;EPSD	COSMIC;CCLE	11.915	Loss
CK1_CK1_CK1-D_CSNK1D_ST	O15055	PER2	P48730	CSNK1D	S662	G658S	658	Missense	distal	-4	no	13.333	13.624	PhosphoSitePlus;EPSD	COSMIC	11.915	Up-regulation
CK1_CK1_CK1-D_CSNK1D_ST	O15055	PER2	P48730	CSNK1D	S662	A655S	655	Missense	distal	-7	no	13.333	12.856	PhosphoSitePlus;EPSD	COSMIC	11.915	Down-regulation
CK1_CK1_CK1-D_CSNK1D_ST	O15055	PER2	P48730	CSNK1D	S665	S665P	665	Missense	central	0	yes	14.104	0.000	EPSD;PhosphoSitePlus	COSMIC;GDSC;CCLE	11.915	Loss
CK1_CK1_CK1-D_CSNK1D_ST	O15055	PER2	P48730	CSNK1D	S665	S665L	665	Missense	central	0	yes	14.104	0.000	EPSD;PhosphoSitePlus	COSMIC;GDSC;CCLE	11.915	Loss
CK1_CK1_CK1-D_CSNK1D_ST	O15055	PER2	P48730	CSNK1D	S665	G658S	658	Missense	distal	-7	no	14.104	13.449	EPSD;PhosphoSitePlus	COSMIC	11.915	Down-regulation
CK1_CK1_CK1-D_CSNK1D_ST	O15055	PER2	P48730	CSNK1D	S668	S665P	665	Missense	distal	-3	no	15.530	11.531	EPSD;PhosphoSitePlus	COSMIC;GDSC;CCLE	11.915	Loss
CK1_CK1_CK1-D_CSNK1D_ST	O15055	PER2	P48730	CSNK1D	S668	S665L	665	Missense	distal	-3	no	15.530	13.326	EPSD;PhosphoSitePlus	COSMIC;GDSC;CCLE	11.915	Down-regulation
CK1_CK1_CK1-D_CSNK1D_ST	O15055	PER2	P48730	CSNK1D	S671	S665P	665	Missense	distal	-6	no	12.258	10.615	EPSD	COSMIC;GDSC;CCLE	11.915	Loss
CK1_CK1_CK1-D_CSNK1D_ST	O15055	PER2	P48730	CSNK1D	S671	S665L	665	Missense	distal	-6	no	12.258	11.563	EPSD	COSMIC;GDSC;CCLE	11.915	Loss
CK1_CK1_CK1-D_CSNK1D_ST	O15055	PER2	P48730	CSNK1D	S696	S700F	700	Missense	distal	4	no	14.592	15.015	EPSD	COSMIC	11.915	Up-regulation
CK1_CK1_CK1-D_CSNK1D_ST	O15055	PER2	P48730	CSNK1D	S771	P770L	770	Missense	proximal	-1	no	15.052	15.346	EPSD	COSMIC	11.915	Up-regulation
CK1_CK1_CK1-D_CSNK1D_ST	O15055	PER2	P48730	CSNK1D	S771	R773Q	773	Missense	proximal	2	no	15.052	15.163	EPSD	COSMIC;GDSC	11.915	Up-regulation
CK1_CK1_CK1-D_CSNK1D_ST	O15055	PER2	P48730	CSNK1D	T774	P770L	770	Missense	distal	-4	no	12.777	12.974	EPSD	COSMIC	11.915	Up-regulation
CK1_CK1_CK1-D_CSNK1D_ST	O15055	PER2	P48730	CSNK1D	T774	R773Q	773	Missense	proximal	-1	no	12.777	13.063	EPSD	COSMIC;GDSC	11.915	Up-regulation
CK1_CK1_CK1-D_CSNK1D_ST	O15055	PER2	P48730	CSNK1D	S810	G815R	815	Missense	distal	5	no	13.908	13.648	EPSD	COSMIC	11.915	Down-regulation
CK1_CK1_CK1-D_CSNK1D_ST	O15055	PER2	P48730	CSNK1D	S810	G812R	812	Missense	proximal	2	no	13.908	13.305	EPSD	COSMIC;GDSC	11.915	Down-regulation
CK1_CK1_CK1-D_CSNK1D_ST	O15055	PER2	P48730	CSNK1D	S810	R805Q	805	Missense	distal	-5	no	13.908	14.685	EPSD	COSMIC;GDSC;CCLE	11.915	Up-regulation
CK1_CK1_CK1-D_CSNK1D_ST	O15055	PER2	P48730	CSNK1D	S977	S971L	971	Missense	distal	-6	no	12.031	11.336	EPSD	COSMIC	11.915	Loss
CK1_CK1_CK1-D_CSNK1D_ST	O15055	PER2	P48730	CSNK1D	S1236	S1229F	1229	Missense	distal	-7	no	12.959	11.879	EPSD	COSMIC	11.915	Loss
CK1_CK1_CK1-D_CSNK1D_ST	O15055	PER2	P48730	CSNK1D	S1236	S1229P	1229	Missense	distal	-7	no	12.959	13.444	EPSD	COSMIC	11.915	Up-regulation
CK1_CK1_CK1-D_CSNK1D_ST	P27707	DCK	P48730	CSNK1D	S11	A14V	14	Missense	distal	3	no	16.389	13.211	EPSD;PhosphoSitePlus	COSMIC;CCLE	11.915	Down-regulation
CK1_CK1_CK1-D_CSNK1D_ST	P27707	DCK	P48730	CSNK1D	S13	A14V	14	Missense	proximal	1	no	9.797	13.498	EPSD	COSMIC;CCLE	11.915	Gain
CK1_CK1_CK1-D_CSNK1D_ST	P27707	DCK	P48730	CSNK1D	S15	A14V	14	Missense	proximal	-1	no	13.354	12.807	EPSD;PhosphoSitePlus	COSMIC;CCLE	11.915	Down-regulation
CK1_CK1_CK1-D_CSNK1D_ST	P27707	DCK	P48730	CSNK1D	T19	A14V	14	Missense	distal	-5	no	16.185	16.679	EPSD	COSMIC;CCLE	11.915	Up-regulation
CK1_CK1_CK1-D_CSNK1D_ST	P10636	MAPT	P48730	CSNK1D	S56	E62K	62	Missense	distal	6	no	16.124	14.326	EPSD	COSMIC	11.915	Down-regulation
CK1_CK1_CK1-D_CSNK1D_ST	P10636	MAPT	P48730	CSNK1D	S64	E62K	62	Missense	proximal	-2	no	15.022	13.747	EPSD	COSMIC	11.915	Down-regulation
CK1_CK1_CK1-D_CSNK1D_ST	P10636	MAPT	P48730	CSNK1D	S68	E62K	62	Missense	distal	-6	no	14.093	13.293	EPSD	COSMIC	11.915	Down-regulation
CK1_CK1_CK1-D_CSNK1D_ST	P10636	MAPT	P48730	CSNK1D	S113	I108V	108	Missense	distal	-5	no	16.388	18.451	EPSD	COSMIC	11.915	Up-regulation
CK1_CK1_CK1-D_CSNK1D_ST	P10636	MAPT	P48730	CSNK1D	S113	G107R	107	Missense	distal	-6	no	16.388	16.807	EPSD	COSMIC	11.915	Up-regulation
CK1_CK1_CK1-D_CSNK1D_ST	P10636	MAPT	P48730	CSNK1D	T123	V122M	122	Missense	proximal	-1	no	12.455	11.339	EPSD	COSMIC	11.915	Loss
CK1_CK1_CK1-D_CSNK1D_ST	P10636	MAPT	P48730	CSNK1D	S171	P175S	175	Missense	distal	4	no	13.725	13.420	EPSD	COSMIC	11.915	Down-regulation
CK1_CK1_CK1-D_CSNK1D_ST	P10636	MAPT	P48730	CSNK1D	S171	A166V	166	Missense	distal	-5	no	13.725	14.219	EPSD	COSMIC;CCLE	11.915	Up-regulation
CK1_CK1_CK1-D_CSNK1D_ST	P10636	MAPT	P48730	CSNK1D	S171	E176G	176	Missense	distal	5	no	13.725	14.158	EPSD	COSMIC	11.915	Up-regulation
CK1_CK1_CK1-D_CSNK1D_ST	P10636	MAPT	P48730	CSNK1D	S171	D177G	177	Missense	distal	6	no	13.725	13.138	EPSD	COSMIC	11.915	Down-regulation
CK1_CK1_CK1-D_CSNK1D_ST	P10636	MAPT	P48730	CSNK1D	S171	E165K	165	Missense	distal	-6	no	13.725	12.925	EPSD	COSMIC	11.915	Down-regulation
CK1_CK1_CK1-D_CSNK1D_ST	P10636	MAPT	P48730	CSNK1D	S171	G172V	172	Missense	proximal	1	no	13.725	13.830	EPSD	COSMIC	11.915	Up-regulation
CK1_CK1_CK1-D_CSNK1D_ST	P10636	MAPT	P48730	CSNK1D	S228	S227N	227	Missense	proximal	-1	no	15.102	15.436	EPSD	COSMIC	11.915	Up-regulation
CK1_CK1_CK1-D_CSNK1D_ST	P10636	MAPT	P48730	CSNK1D	S228	S227I	227	Missense	proximal	-1	no	15.102	16.182	EPSD	COSMIC	11.915	Up-regulation
CK1_CK1_CK1-D_CSNK1D_ST	P10636	MAPT	P48730	CSNK1D	S228	E226K	226	Missense	proximal	-2	no	15.102	13.826	EPSD	COSMIC	11.915	Down-regulation
CK1_CK1_CK1-D_CSNK1D_ST	P10636	MAPT	P48730	CSNK1D	S228	Q230R	230	Missense	proximal	2	no	15.102	14.991	EPSD	COSMIC	11.915	Down-regulation
CK1_CK1_CK1-D_CSNK1D_ST	P10636	MAPT	P48730	CSNK1D	S228	P233S	233	Missense	distal	5	no	15.102	15.240	EPSD	COSMIC	11.915	Up-regulation
CK1_CK1_CK1-D_CSNK1D_ST	P10636	MAPT	P48730	CSNK1D	S228	D225E	225	Missense	distal	-3	no	15.102	14.221	EPSD	COSMIC	11.915	Down-regulation
CK1_CK1_CK1-D_CSNK1D_ST	P10636	MAPT	P48730	CSNK1D	S228	S227G	227	Missense	proximal	-1	no	15.102	15.041	EPSD	COSMIC	11.915	Down-regulation
CK1_CK1_CK1-D_CSNK1D_ST	P10636	MAPT	P48730	CSNK1D	S228	S235L	235	Missense	distal	7	no	15.102	16.907	EPSD	COSMIC	11.915	Up-regulation
CK1_CK1_CK1-D_CSNK1D_ST	P10636	MAPT	P48730	CSNK1D	S238	A237T	237	Missense	proximal	-1	no	14.130	12.776	EPSD	COSMIC	11.915	Down-regulation
CK1_CK1_CK1-D_CSNK1D_ST	P10636	MAPT	P48730	CSNK1D	S238	A240S	240	Missense	proximal	2	no	14.130	13.397	EPSD	COSMIC	11.915	Down-regulation
CK1_CK1_CK1-D_CSNK1D_ST	P10636	MAPT	P48730	CSNK1D	S238	D242N	242	Missense	distal	4	no	14.130	13.429	EPSD	COSMIC	11.915	Down-regulation
CK1_CK1_CK1-D_CSNK1D_ST	P10636	MAPT	P48730	CSNK1D	S238	R244W	244	Missense	distal	6	no	14.130	16.158	EPSD	COSMIC	11.915	Up-regulation
CK1_CK1_CK1-D_CSNK1D_ST	P10636	MAPT	P48730	CSNK1D	S238	S238P	238	Missense	central	0	yes	14.130	0.000	EPSD	COSMIC	11.915	Loss
CK1_CK1_CK1-D_CSNK1D_ST	P10636	MAPT	P48730	CSNK1D	S238	P233S	233	Missense	distal	-5	no	14.130	14.137	EPSD	COSMIC	11.915	Up-regulation
CK1_CK1_CK1-D_CSNK1D_ST	P10636	MAPT	P48730	CSNK1D	S238	S238F	238	Missense	central	0	yes	14.130	0.000	EPSD	COSMIC	11.915	Loss
CK1_CK1_CK1-D_CSNK1D_ST	P10636	MAPT	P48730	CSNK1D	S238	G243D	243	Missense	distal	5	no	14.130	13.674	EPSD	COSMIC	11.915	Down-regulation
CK1_CK1_CK1-D_CSNK1D_ST	P10636	MAPT	P48730	CSNK1D	S238	S235L	235	Missense	distal	-3	no	14.130	11.926	EPSD	COSMIC	11.915	Down-regulation
CK1_CK1_CK1-D_CSNK1D_ST	P10636	MAPT	P48730	CSNK1D	S355	A361S	361	Missense	distal	6	no	11.733	13.373	EPSD	COSMIC;GDSC;CCLE	11.915	Gain
CK1_CK1_CK1-D_CSNK1D_ST	P10636	MAPT	P48730	CSNK1D	S355	P354L	354	Missense	proximal	-1	no	11.733	12.027	EPSD	COSMIC	11.915	Gain
CK1_CK1_CK1-D_CSNK1D_ST	P10636	MAPT	P48730	CSNK1D	S388	G385V	385	Missense	distal	-3	no	14.560	11.967	EPSD	COSMIC	11.915	Down-regulation
CK1_CK1_CK1-D_CSNK1D_ST	P10636	MAPT	P48730	CSNK1D	S388	T386I	386	Missense	proximal	-2	no	14.560	8.916	EPSD	COSMIC	11.915	Loss
CK1_CK1_CK1-D_CSNK1D_ST	P10636	MAPT	P48730	CSNK1D	S388	D389N	389	Missense	proximal	1	no	14.560	13.252	EPSD	COSMIC;GDSC;CCLE	11.915	Down-regulation
CK1_CK1_CK1-D_CSNK1D_ST	P10636	MAPT	P48730	CSNK1D	S512	P506S	506	Missense	distal	-6	no	11.717	13.360	EPSD	COSMIC	11.915	Gain
CK1_CK1_CK1-D_CSNK1D_ST	P10636	MAPT	P48730	CSNK1D	S512	P506L	506	Missense	distal	-6	no	11.717	12.665	EPSD	COSMIC	11.915	Gain
CK1_CK1_CK1-D_CSNK1D_ST	P10636	MAPT	P48730	CSNK1D	S515	R511C	511	Missense	distal	-4	no	11.805	12.221	EPSD	COSMIC;CCLE	11.915	Gain
CK1_CK1_CK1-D_CSNK1D_ST	P10636	MAPT	P48730	CSNK1D	S515	G509V	509	Missense	distal	-6	no	11.805	12.299	EPSD	COSMIC	11.915	Gain
CK1_CK1_CK1-D_CSNK1D_ST	P10636	MAPT	P48730	CSNK1D	S519	R526H	526	Missense	distal	7	no	10.261	13.214	EPSD	COSMIC	11.915	Gain
CK1_CK1_CK1-D_CSNK1D_ST	P10636	MAPT	P48730	CSNK1D	T522	G521V	521	Missense	proximal	-1	no	14.745	15.069	EPSD	COSMIC	11.915	Up-regulation
CK1_CK1_CK1-D_CSNK1D_ST	P10636	MAPT	P48730	CSNK1D	T522	R526H	526	Missense	distal	4	no	14.745	15.264	EPSD	COSMIC	11.915	Up-regulation
CK1_CK1_CK1-D_CSNK1D_ST	P10636	MAPT	P48730	CSNK1D	T522	G518V	518	Missense	distal	-4	no	14.745	14.570	EPSD	COSMIC	11.915	Down-regulation
CK1_CK1_CK1-D_CSNK1D_ST	P10636	MAPT	P48730	CSNK1D	T522	R528S	528	Missense	distal	6	no	14.745	17.656	EPSD	COSMIC	11.915	Up-regulation
CK1_CK1_CK1-D_CSNK1D_ST	P10636	MAPT	P48730	CSNK1D	S525	G521V	521	Missense	distal	-4	no	12.146	11.971	EPSD	COSMIC	11.915	Down-regulation
CK1_CK1_CK1-D_CSNK1D_ST	P10636	MAPT	P48730	CSNK1D	S525	R526H	526	Missense	proximal	1	no	12.146	14.266	EPSD	COSMIC	11.915	Up-regulation
CK1_CK1_CK1-D_CSNK1D_ST	P10636	MAPT	P48730	CSNK1D	S525	G518V	518	Missense	distal	-7	no	12.146	9.891	EPSD	COSMIC	11.915	Loss
CK1_CK1_CK1-D_CSNK1D_ST	P10636	MAPT	P48730	CSNK1D	S525	R528S	528	Missense	distal	3	no	12.146	15.390	EPSD	COSMIC	11.915	Up-regulation
CK1_CK1_CK1-D_CSNK1D_ST	P10636	MAPT	P48730	CSNK1D	S525	P530S	530	Missense	distal	5	no	12.146	12.284	EPSD	COSMIC	11.915	Up-regulation
CK1_CK1_CK1-D_CSNK1D_ST	P10636	MAPT	P48730	CSNK1D	S669	D662G	662	Missense	distal	-7	no	11.479	12.260	EPSD	COSMIC	11.915	Gain
CK1_CK1_CK1-D_CSNK1D_ST	P10636	MAPT	P48730	CSNK1D	S669	K670N	670	Missense	proximal	1	no	11.479	13.634	EPSD	COSMIC	11.915	Gain
CK1_CK1_CK1-D_CSNK1D_ST	P10636	MAPT	P48730	CSNK1D	S669	K664N	664	Missense	distal	-5	no	11.479	13.723	EPSD	COSMIC	11.915	Gain
CK1_CK1_CK1-D_CSNK1D_ST	P10636	MAPT	P48730	CSNK1D	S713	E708D	708	Missense	distal	-5	no	13.580	12.560	EPSD	COSMIC	11.915	Down-regulation
CK1_CK1_CK1-D_CSNK1D_ST	P10636	MAPT	P48730	CSNK1D	S713	G706R	706	Missense	distal	-7	no	13.580	11.768	EPSD	COSMIC	11.915	Loss
CK1_CK1_CK1-D_CSNK1D_ST	P10636	MAPT	P48730	CSNK1D	S713	V710M	710	Missense	distal	-3	no	13.580	14.986	EPSD	COSMIC	11.915	Up-regulation
CK1_CK1_CK1-D_CSNK1D_ST	P10636	MAPT	P48730	CSNK1D	S713	E708K	708	Missense	distal	-5	no	13.580	12.003	EPSD	COSMIC	11.915	Down-regulation
CK1_CK1_CK1-D_CSNK1D_ST	P10636	MAPT	P48730	CSNK1D	S713	V710A	710	Missense	distal	-3	no	13.580	14.387	EPSD	COSMIC	11.915	Up-regulation
CK1_CK1_CK1-D_CSNK1D_ST	P10636	MAPT	P48730	CSNK1D	S721	R723W	723	Missense	proximal	2	no	18.393	14.764	EPSD	COSMIC	11.915	Down-regulation
CK1_CK1_CK1-D_CSNK1D_ST	P10636	MAPT	P48730	CSNK1D	S721	V728M	728	Missense	distal	7	no	18.393	18.597	EPSD	COSMIC	11.915	Up-regulation
CK1_CK1_CK1-D_CSNK1D_ST	P10636	MAPT	P48730	CSNK1D	S721	V728A	728	Missense	distal	7	no	18.393	17.471	EPSD	COSMIC	11.915	Down-regulation
CK1_CK1_CK1-D_CSNK1D_ST	P10636	MAPT	P48730	CSNK1D	S733	G732S	732	Missense	proximal	-1	no	15.204	15.265	EPSD	COSMIC	11.915	Up-regulation
CK1_CK1_CK1-D_CSNK1D_ST	P10636	MAPT	P48730	CSNK1D	S733	D735N	735	Missense	proximal	2	no	15.204	14.681	EPSD	COSMIC	11.915	Down-regulation
CK1_CK1_CK1-D_CSNK1D_ST	P10636	MAPT	P48730	CSNK1D	S733	G732C	732	Missense	proximal	-1	no	15.204	14.776	EPSD	COSMIC	11.915	Down-regulation
CK1_CK1_CK1-D_CSNK1D_ST	P10636	MAPT	P48730	CSNK1D	S733	V728M	728	Missense	distal	-5	no	15.204	13.651	EPSD	COSMIC	11.915	Down-regulation
CK1_CK1_CK1-D_CSNK1D_ST	P10636	MAPT	P48730	CSNK1D	S733	V728A	728	Missense	distal	-5	no	15.204	14.711	EPSD	COSMIC	11.915	Down-regulation
CK1_CK1_CK1-D_CSNK1D_ST	Q99814	EPAS1	P48730	CSNK1D	S383	S383C	383	Missense	central	0	yes	16.536	0.000	EPSD;PhosphoSitePlus	COSMIC	11.915	Loss
CK1_CK1_CK1-D_CSNK1D_ST	Q99814	EPAS1	P48730	CSNK1D	S383	A381V	381	Missense	proximal	-2	no	16.536	13.836	EPSD;PhosphoSitePlus	COSMIC	11.915	Down-regulation
CK1_CK1_CK1-D_CSNK1D_ST	Q13148	TARDBP	P48730	CSNK1D	S20	D13N	13	Missense	distal	-7	no	15.835	16.699	EPSD	COSMIC;GDSC;CCLE	11.915	Up-regulation
CK1_CK1_CK1-D_CSNK1D_ST	Q13148	TARDBP	P48730	CSNK1D	T88	D86Y	86	Missense	proximal	-2	no	13.047	8.615	EPSD	COSMIC	11.915	Loss
CK1_CK1_CK1-D_CSNK1D_ST	Q13148	TARDBP	P48730	CSNK1D	T88	N81D	81	Missense	distal	-7	no	13.047	12.183	EPSD	COSMIC;GDSC;CCLE	11.915	Down-regulation
CK1_CK1_CK1-D_CSNK1D_ST	Q13148	TARDBP	P48730	CSNK1D	T88	M85V	85	Missense	distal	-3	no	13.047	11.642	EPSD	COSMIC	11.915	Loss
CK1_CK1_CK1-D_CSNK1D_ST	Q13148	TARDBP	P48730	CSNK1D	S92	D86Y	86	Missense	distal	-6	no	14.725	13.134	EPSD;PhosphoSitePlus	COSMIC	11.915	Down-regulation
CK1_CK1_CK1-D_CSNK1D_ST	Q13148	TARDBP	P48730	CSNK1D	S92	M85V	85	Missense	distal	-7	no	14.725	13.322	EPSD;PhosphoSitePlus	COSMIC	11.915	Down-regulation
CK1_CK1_CK1-D_CSNK1D_ST	Q13148	TARDBP	P48730	CSNK1D	S317	A321V	321	Missense	distal	4	no	13.388	14.639	EPSD;PhosphoSitePlus	COSMIC;GDSC;CCLE	11.915	Up-regulation
CK1_CK1_CK1-D_CSNK1D_ST	Q13148	TARDBP	P48730	CSNK1D	S333	G338D	338	Missense	distal	5	no	14.810	14.353	EPSD;PhosphoSitePlus	COSMIC	11.915	Down-regulation
CK1_CK1_CK1-D_CSNK1D_ST	Q13148	TARDBP	P48730	CSNK1D	S333	Q327K	327	Missense	distal	-6	no	14.810	14.832	EPSD;PhosphoSitePlus	COSMIC	11.915	Up-regulation
CK1_CK1_CK1-D_CSNK1D_ST	Q13148	TARDBP	P48730	CSNK1D	S333	A329V	329	Missense	distal	-4	no	14.810	14.043	EPSD;PhosphoSitePlus	COSMIC	11.915	Down-regulation
CK1_CK1_CK1-D_CSNK1D_ST	Q13148	TARDBP	P48730	CSNK1D	S350	Q356K	356	Missense	distal	6	no	15.183	15.138	EPSD	COSMIC	11.915	Down-regulation
CK1_CK1_CK1-D_CSNK1D_ST	Q13148	TARDBP	P48730	CSNK1D	S350	N355S	355	Missense	distal	5	no	15.183	15.281	EPSD	COSMIC	11.915	Up-regulation
CK1_CK1_CK1-D_CSNK1D_ST	Q13148	TARDBP	P48730	CSNK1D	S375	G368C	368	Missense	distal	-7	no	12.222	10.523	EPSD	COSMIC	11.915	Loss
CK1_CK1_CK1-D_CSNK1D_ST	Q13148	TARDBP	P48730	CSNK1D	S389	N390D	390	Missense	proximal	1	no	12.633	13.941	EPSD;PhosphoSitePlus	COSMIC	11.915	Up-regulation
CK1_CK1_CK1-D_CSNK1D_ST	Q13148	TARDBP	P48730	CSNK1D	S393	N390D	390	Missense	distal	-3	no	18.774	21.216	PhosphoSitePlus;EPSD	COSMIC	11.915	Up-regulation
CK1_CK1_CK1-D_CSNK1D_ST	Q13148	TARDBP	P48730	CSNK1D	S395	N390D	390	Missense	distal	-5	no	17.157	15.470	EPSD;PhosphoSitePlus	COSMIC	11.915	Down-regulation
CK1_CK1_CK1-D_CSNK1D_ST	O14641	DVL2	P48730	CSNK1D	S59	K54N	54	Missense	distal	-5	no	9.997	12.242	EPSD	COSMIC	11.915	Gain
CK1_CK1_CK1-D_CSNK1D_ST	O14641	DVL2	P48730	CSNK1D	S169	G175W	175	Missense	distal	6	no	12.854	13.442	EPSD	COSMIC	11.915	Up-regulation
CK1_CK1_CK1-D_CSNK1D_ST	O14641	DVL2	P48730	CSNK1D	S169	H172D	172	Missense	distal	3	no	12.854	13.217	EPSD	COSMIC;CCLE	11.915	Up-regulation
CK1_CK1_CK1-D_CSNK1D_ST	O14641	DVL2	P48730	CSNK1D	S195	L198P	198	Missense	distal	3	no	12.326	11.346	EPSD	COSMIC	11.915	Loss
CK1_CK1_CK1-D_CSNK1D_ST	O14641	DVL2	P48730	CSNK1D	S207	E214G	214	Missense	distal	7	no	12.071	12.255	EPSD	COSMIC	11.915	Up-regulation
CK1_CK1_CK1-D_CSNK1D_ST	O14641	DVL2	P48730	CSNK1D	S211	E214G	214	Missense	distal	3	no	13.144	12.700	EPSD	COSMIC	11.915	Down-regulation
CK1_CK1_CK1-D_CSNK1D_ST	O14641	DVL2	P48730	CSNK1D	S218	T224M	224	Missense	distal	6	no	10.724	14.512	EPSD	COSMIC	11.915	Gain
CK1_CK1_CK1-D_CSNK1D_ST	O14641	DVL2	P48730	CSNK1D	T224	T224M	224	Missense	central	0	yes	12.393	0.000	EPSD;PhosphoSitePlus	COSMIC	11.915	Loss
CK1_CK1_CK1-D_CSNK1D_ST	O14641	DVL2	P48730	CSNK1D	T224	S230F	230	Missense	distal	6	no	12.393	11.845	EPSD;PhosphoSitePlus	COSMIC	11.915	Loss
CK1_CK1_CK1-D_CSNK1D_ST	O14641	DVL2	P48730	CSNK1D	T224	R231Q	231	Missense	distal	7	no	12.393	13.663	EPSD;PhosphoSitePlus	COSMIC	11.915	Up-regulation
CK1_CK1_CK1-D_CSNK1D_ST	O14641	DVL2	P48730	CSNK1D	S228	L233R	233	Missense	distal	5	no	11.514	12.440	EPSD	COSMIC	11.915	Gain
CK1_CK1_CK1-D_CSNK1D_ST	O14641	DVL2	P48730	CSNK1D	S228	R231Q	231	Missense	distal	3	no	11.514	13.308	EPSD	COSMIC	11.915	Gain
CK1_CK1_CK1-D_CSNK1D_ST	O14641	DVL2	P48730	CSNK1D	S286	I282T	282	Missense	distal	-4	no	13.541	13.164	EPSD	COSMIC	11.915	Down-regulation
CK1_CK1_CK1-D_CSNK1D_ST	O14641	DVL2	P48730	CSNK1D	S358	P359T	359	Missense	proximal	1	no	15.495	14.321	EPSD	COSMIC;GDSC;CCLE	11.915	Down-regulation
CK1_CK1_CK1-D_CSNK1D_ST	O14641	DVL2	P48730	CSNK1D	T403	D410H	410	Missense	distal	7	no	12.220	14.629	EPSD	COSMIC	11.915	Up-regulation
CK1_CK1_CK1-D_CSNK1D_ST	O14641	DVL2	P48730	CSNK1D	S425	S418F	418	Missense	distal	-7	no	13.355	12.275	EPSD	COSMIC	11.915	Down-regulation
CK1_CK1_CK1-D_CSNK1D_ST	O14641	DVL2	P48730	CSNK1D	S425	A429T	429	Missense	distal	4	no	13.355	13.803	EPSD	COSMIC	11.915	Up-regulation
CK1_CK1_CK1-D_CSNK1D_ST	O14641	DVL2	P48730	CSNK1D	S580	T575N	575	Missense	distal	-5	no	10.067	13.198	EPSD	COSMIC	11.915	Gain
CK1_CK1_CK1-D_CSNK1D_ST	O14641	DVL2	P48730	CSNK1D	S616	G617S	617	Missense	proximal	1	no	16.189	13.030	EPSD	COSMIC;GDSC;CCLE	11.915	Down-regulation
CK1_CK1_CK1-D_CSNK1D_ST	O14641	DVL2	P48730	CSNK1D	S618	S625P	625	Missense	distal	7	no	11.808	12.669	EPSD	COSMIC	11.915	Gain
CK1_CK1_CK1-D_CSNK1D_ST	O14641	DVL2	P48730	CSNK1D	S618	P624L	624	Missense	distal	6	no	11.808	12.414	EPSD	COSMIC	11.915	Gain
CK1_CK1_CK1-D_CSNK1D_ST	O14641	DVL2	P48730	CSNK1D	S620	R627Q	627	Missense	distal	7	no	12.404	13.674	EPSD	COSMIC	11.915	Up-regulation
CK1_CK1_CK1-D_CSNK1D_ST	O14641	DVL2	P48730	CSNK1D	S620	G617S	617	Missense	distal	-3	no	12.404	13.152	EPSD	COSMIC;GDSC;CCLE	11.915	Up-regulation
CK1_CK1_CK1-D_CSNK1D_ST	O14641	DVL2	P48730	CSNK1D	S620	S625P	625	Missense	distal	5	no	12.404	12.266	EPSD	COSMIC	11.915	Down-regulation
CK1_CK1_CK1-D_CSNK1D_ST	O14641	DVL2	P48730	CSNK1D	S620	P624L	624	Missense	distal	4	no	12.404	12.463	EPSD	COSMIC	11.915	Up-regulation
CK1_CK1_CK1-D_CSNK1D_ST	Q00987	MDM2	P48730	CSNK1D	S17	E23K	23	Missense	distal	6	no	13.405	11.607	EPSD	COSMIC	11.915	Loss
CK1_CK1_CK1-D_CSNK1D_ST	Q00987	MDM2	P48730	CSNK1D	S17	T10I	10	Missense	distal	-7	no	13.405	14.344	EPSD	COSMIC	11.915	Up-regulation
CK1_CK1_CK1-D_CSNK1D_ST	Q00987	MDM2	P48730	CSNK1D	S17	D11N	11	Missense	distal	-6	no	13.405	13.484	EPSD	COSMIC	11.915	Up-regulation
CK1_CK1_CK1-D_CSNK1D_ST	Q00987	MDM2	P48730	CSNK1D	S17	T16I	16	Missense	proximal	-1	no	13.405	15.029	EPSD	COSMIC	11.915	Up-regulation
CK1_CK1_CK1-D_CSNK1D_ST	Q00987	MDM2	P48730	CSNK1D	T49	Y56F	56	Missense	distal	7	no	11.079	12.234	EPSD	COSMIC	11.915	Gain
CK1_CK1_CK1-D_CSNK1D_ST	Q00987	MDM2	P48730	CSNK1D	S118	E114D	114	Missense	distal	-4	no	16.891	16.751	EPSD;PhosphoSitePlus	COSMIC	11.915	Down-regulation
CK1_CK1_CK1-D_CSNK1D_ST	Q00987	MDM2	P48730	CSNK1D	S118	D117N	117	Missense	proximal	-1	no	16.891	16.889	EPSD;PhosphoSitePlus	COSMIC	11.915	Down-regulation
CK1_CK1_CK1-D_CSNK1D_ST	Q00987	MDM2	P48730	CSNK1D	S118	E124K	124	Missense	distal	6	no	16.891	15.093	EPSD;PhosphoSitePlus	COSMIC	11.915	Down-regulation
CK1_CK1_CK1-D_CSNK1D_ST	Q00987	MDM2	P48730	CSNK1D	S118	S121F	121	Missense	distal	3	no	16.891	15.731	EPSD;PhosphoSitePlus	COSMIC	11.915	Down-regulation
CK1_CK1_CK1-D_CSNK1D_ST	Q00987	MDM2	P48730	CSNK1D	S121	E114D	114	Missense	distal	-7	no	17.914	16.808	EPSD;PhosphoSitePlus	COSMIC	11.915	Down-regulation
CK1_CK1_CK1-D_CSNK1D_ST	Q00987	MDM2	P48730	CSNK1D	S121	D117N	117	Missense	distal	-4	no	17.914	17.907	EPSD;PhosphoSitePlus	COSMIC	11.915	Down-regulation
CK1_CK1_CK1-D_CSNK1D_ST	Q00987	MDM2	P48730	CSNK1D	S121	E124K	124	Missense	distal	3	no	17.914	17.024	EPSD;PhosphoSitePlus	COSMIC	11.915	Down-regulation
CK1_CK1_CK1-D_CSNK1D_ST	Q00987	MDM2	P48730	CSNK1D	S121	S121F	121	Missense	central	0	yes	17.914	0.000	EPSD;PhosphoSitePlus	COSMIC	11.915	Loss
CK1_CK1_CK1-D_CSNK1D_ST	Q00987	MDM2	P48730	CSNK1D	S121	C127Y	127	Missense	distal	6	no	17.914	20.063	EPSD;PhosphoSitePlus	COSMIC	11.915	Up-regulation
CK1_CK1_CK1-D_CSNK1D_ST	Q00987	MDM2	P48730	CSNK1D	S121	H128D	128	Missense	distal	7	no	17.914	15.504	EPSD;PhosphoSitePlus	COSMIC	11.915	Down-regulation
CK1_CK1_CK1-D_CSNK1D_ST	Q00987	MDM2	P48730	CSNK1D	S166	E170D	170	Missense	distal	4	no	12.934	13.557	EPSD;PhosphoSitePlus	COSMIC	11.915	Up-regulation
CK1_CK1_CK1-D_CSNK1D_ST	Q00987	MDM2	P48730	CSNK1D	S166	S160F	160	Missense	distal	-6	no	12.934	12.206	EPSD;PhosphoSitePlus	COSMIC	11.915	Down-regulation
CK1_CK1_CK1-D_CSNK1D_ST	Q00987	MDM2	P48730	CSNK1D	S166	S159R	159	Missense	distal	-7	no	12.934	11.777	EPSD;PhosphoSitePlus	COSMIC	11.915	Loss
CK1_CK1_CK1-D_CSNK1D_ST	Q00987	MDM2	P48730	CSNK1D	S166	S159G	159	Missense	distal	-7	no	12.934	13.589	EPSD;PhosphoSitePlus	COSMIC	11.915	Up-regulation
CK1_CK1_CK1-D_CSNK1D_ST	Q00987	MDM2	P48730	CSNK1D	S166	D173Y	173	Missense	distal	7	no	12.934	12.723	EPSD;PhosphoSitePlus	COSMIC	11.915	Down-regulation
CK1_CK1_CK1-D_CSNK1D_ST	Q00987	MDM2	P48730	CSNK1D	S166	S166C	166	Missense	central	0	yes	12.934	0.000	EPSD;PhosphoSitePlus	COSMIC	11.915	Loss
CK1_CK1_CK1-D_CSNK1D_ST	Q00987	MDM2	P48730	CSNK1D	S166	E167Q	167	Missense	proximal	1	no	12.934	12.249	EPSD;PhosphoSitePlus	COSMIC	11.915	Down-regulation
CK1_CK1_CK1-D_CSNK1D_ST	Q00987	MDM2	P48730	CSNK1D	S166	S159N	159	Missense	distal	-7	no	12.934	13.672	EPSD;PhosphoSitePlus	COSMIC	11.915	Up-regulation
CK1_CK1_CK1-D_CSNK1D_ST	Q00987	MDM2	P48730	CSNK1D	S166	R161T	161	Missense	distal	-5	no	12.934	11.611	EPSD;PhosphoSitePlus	COSMIC	11.915	Loss
CK1_CK1_CK1-D_CSNK1D_ST	Q00987	MDM2	P48730	CSNK1D	S166	S166F	166	Missense	central	0	yes	12.934	0.000	EPSD;PhosphoSitePlus	COSMIC	11.915	Loss
CK1_CK1_CK1-D_CSNK1D_ST	Q00987	MDM2	P48730	CSNK1D	S172	E170D	170	Missense	proximal	-2	no	16.843	16.471	EPSD;PhosphoSitePlus	COSMIC	11.915	Down-regulation
CK1_CK1_CK1-D_CSNK1D_ST	Q00987	MDM2	P48730	CSNK1D	S172	E178K	178	Missense	distal	6	no	16.843	15.044	EPSD;PhosphoSitePlus	COSMIC	11.915	Down-regulation
CK1_CK1_CK1-D_CSNK1D_ST	Q00987	MDM2	P48730	CSNK1D	S172	S176F	176	Missense	distal	4	no	16.843	17.266	EPSD;PhosphoSitePlus	COSMIC	11.915	Up-regulation
CK1_CK1_CK1-D_CSNK1D_ST	Q00987	MDM2	P48730	CSNK1D	S172	G177D	177	Missense	distal	5	no	16.843	16.386	EPSD;PhosphoSitePlus	COSMIC	11.915	Down-regulation
CK1_CK1_CK1-D_CSNK1D_ST	Q00987	MDM2	P48730	CSNK1D	S172	R179P	179	Missense	distal	7	no	16.843	17.177	EPSD;PhosphoSitePlus	COSMIC	11.915	Up-regulation
CK1_CK1_CK1-D_CSNK1D_ST	Q00987	MDM2	P48730	CSNK1D	S172	D173Y	173	Missense	proximal	1	no	16.843	14.323	EPSD;PhosphoSitePlus	COSMIC	11.915	Down-regulation
CK1_CK1_CK1-D_CSNK1D_ST	Q00987	MDM2	P48730	CSNK1D	S172	S166C	166	Missense	distal	-6	no	16.843	16.583	EPSD;PhosphoSitePlus	COSMIC	11.915	Down-regulation
CK1_CK1_CK1-D_CSNK1D_ST	Q00987	MDM2	P48730	CSNK1D	S172	E167Q	167	Missense	distal	-5	no	16.843	16.479	EPSD;PhosphoSitePlus	COSMIC	11.915	Down-regulation
CK1_CK1_CK1-D_CSNK1D_ST	Q00987	MDM2	P48730	CSNK1D	S172	S166F	166	Missense	distal	-6	no	16.843	16.114	EPSD;PhosphoSitePlus	COSMIC	11.915	Down-regulation
CK1_CK1_CK1-D_CSNK1D_ST	Q00987	MDM2	P48730	CSNK1D	S176	E170D	170	Missense	distal	-6	no	20.743	20.056	EPSD;PhosphoSitePlus	COSMIC	11.915	Down-regulation
CK1_CK1_CK1-D_CSNK1D_ST	Q00987	MDM2	P48730	CSNK1D	S176	R183H	183	Missense	distal	7	no	20.743	23.697	EPSD;PhosphoSitePlus	COSMIC	11.915	Up-regulation
CK1_CK1_CK1-D_CSNK1D_ST	Q00987	MDM2	P48730	CSNK1D	S176	E178K	178	Missense	proximal	2	no	20.743	19.981	EPSD;PhosphoSitePlus	COSMIC	11.915	Down-regulation
CK1_CK1_CK1-D_CSNK1D_ST	Q00987	MDM2	P48730	CSNK1D	S176	S176F	176	Missense	central	0	yes	20.743	0.000	EPSD;PhosphoSitePlus	COSMIC	11.915	Loss
CK1_CK1_CK1-D_CSNK1D_ST	Q00987	MDM2	P48730	CSNK1D	S176	G177D	177	Missense	proximal	1	no	20.743	20.212	EPSD;PhosphoSitePlus	COSMIC	11.915	Down-regulation
CK1_CK1_CK1-D_CSNK1D_ST	Q00987	MDM2	P48730	CSNK1D	S176	R183C	183	Missense	distal	7	no	20.743	18.829	EPSD;PhosphoSitePlus	COSMIC	11.915	Down-regulation
CK1_CK1_CK1-D_CSNK1D_ST	Q00987	MDM2	P48730	CSNK1D	S176	R179P	179	Missense	distal	3	no	20.743	21.218	EPSD;PhosphoSitePlus	COSMIC	11.915	Up-regulation
CK1_CK1_CK1-D_CSNK1D_ST	Q00987	MDM2	P48730	CSNK1D	S176	D173Y	173	Missense	distal	-3	no	20.743	19.239	EPSD;PhosphoSitePlus	COSMIC	11.915	Down-regulation
CK1_CK1_CK1-D_CSNK1D_ST	Q00987	MDM2	P48730	CSNK1D	S190	R183H	183	Missense	distal	-7	no	12.818	11.975	EPSD	COSMIC	11.915	Down-regulation
CK1_CK1_CK1-D_CSNK1D_ST	Q00987	MDM2	P48730	CSNK1D	S190	I189V	189	Missense	proximal	-1	no	12.818	12.002	EPSD	COSMIC	11.915	Down-regulation
CK1_CK1_CK1-D_CSNK1D_ST	Q00987	MDM2	P48730	CSNK1D	S190	K185R	185	Missense	distal	-5	no	12.818	13.254	EPSD	COSMIC	11.915	Up-regulation
CK1_CK1_CK1-D_CSNK1D_ST	Q00987	MDM2	P48730	CSNK1D	S190	S190F	190	Missense	central	0	yes	12.818	0.000	EPSD	COSMIC	11.915	Loss
CK1_CK1_CK1-D_CSNK1D_ST	Q00987	MDM2	P48730	CSNK1D	S190	R183C	183	Missense	distal	-7	no	12.818	12.931	EPSD	COSMIC	11.915	Up-regulation
CK1_CK1_CK1-D_CSNK1D_ST	Q00987	MDM2	P48730	CSNK1D	S190	S196F	196	Missense	distal	6	no	12.818	12.271	EPSD	COSMIC	11.915	Down-regulation
CK1_CK1_CK1-D_CSNK1D_ST	Q00987	MDM2	P48730	CSNK1D	S220	N221I	221	Missense	proximal	1	no	18.742	17.988	EPSD;PhosphoSitePlus	COSMIC	11.915	Down-regulation
CK1_CK1_CK1-D_CSNK1D_ST	Q00987	MDM2	P48730	CSNK1D	S220	D223H	223	Missense	distal	3	no	18.742	18.379	EPSD;PhosphoSitePlus	COSMIC	11.915	Down-regulation
CK1_CK1_CK1-D_CSNK1D_ST	Q00987	MDM2	P48730	CSNK1D	S220	D223E	223	Missense	distal	3	no	18.742	19.063	EPSD;PhosphoSitePlus	COSMIC	11.915	Up-regulation
CK1_CK1_CK1-D_CSNK1D_ST	Q00987	MDM2	P48730	CSNK1D	S220	T218M	218	Missense	proximal	-2	no	18.742	15.496	EPSD;PhosphoSitePlus	COSMIC	11.915	Down-regulation
CK1_CK1_CK1-D_CSNK1D_ST	Q00987	MDM2	P48730	CSNK1D	S220	S220L	220	Missense	central	0	yes	18.742	0.000	EPSD;PhosphoSitePlus	COSMIC	11.915	Loss
CK1_CK1_CK1-D_CSNK1D_ST	Q00987	MDM2	P48730	CSNK1D	S220	D223N	223	Missense	distal	3	no	18.742	19.183	EPSD;PhosphoSitePlus	COSMIC	11.915	Up-regulation
CK1_CK1_CK1-D_CSNK1D_ST	Q00987	MDM2	P48730	CSNK1D	S220	D225N	225	Missense	distal	5	no	18.742	19.173	EPSD;PhosphoSitePlus	COSMIC	11.915	Up-regulation
CK1_CK1_CK1-D_CSNK1D_ST	Q00987	MDM2	P48730	CSNK1D	S220	T216S	216	Missense	distal	-4	no	18.742	19.138	EPSD;PhosphoSitePlus	COSMIC	11.915	Up-regulation
CK1_CK1_CK1-D_CSNK1D_ST	Q00987	MDM2	P48730	CSNK1D	S220	S220W	220	Missense	central	0	yes	18.742	0.000	EPSD;PhosphoSitePlus	COSMIC	11.915	Loss
CK1_CK1_CK1-D_CSNK1D_ST	Q00987	MDM2	P48730	CSNK1D	S220	S215C	215	Missense	distal	-5	no	18.742	18.152	EPSD;PhosphoSitePlus	COSMIC	11.915	Down-regulation
CK1_CK1_CK1-D_CSNK1D_ST	Q00987	MDM2	P48730	CSNK1D	S220	S213N	213	Missense	distal	-7	no	18.742	19.479	EPSD;PhosphoSitePlus	COSMIC	11.915	Up-regulation
CK1_CK1_CK1-D_CSNK1D_ST	Q00987	MDM2	P48730	CSNK1D	S220	E214K	214	Missense	distal	-6	no	18.742	17.942	EPSD;PhosphoSitePlus	COSMIC	11.915	Down-regulation
CK1_CK1_CK1-D_CSNK1D_ST	Q00987	MDM2	P48730	CSNK1D	S229	D223H	223	Missense	distal	-6	no	13.469	12.326	EPSD;PhosphoSitePlus	COSMIC	11.915	Down-regulation
CK1_CK1_CK1-D_CSNK1D_ST	Q00987	MDM2	P48730	CSNK1D	S229	D223E	223	Missense	distal	-6	no	13.469	14.156	EPSD;PhosphoSitePlus	COSMIC	11.915	Up-regulation
CK1_CK1_CK1-D_CSNK1D_ST	Q00987	MDM2	P48730	CSNK1D	S229	S229N	229	Missense	central	0	yes	13.469	0.000	EPSD;PhosphoSitePlus	COSMIC	11.915	Loss
CK1_CK1_CK1-D_CSNK1D_ST	Q00987	MDM2	P48730	CSNK1D	S229	E230Q	230	Missense	proximal	1	no	13.469	12.783	EPSD;PhosphoSitePlus	COSMIC	11.915	Down-regulation
CK1_CK1_CK1-D_CSNK1D_ST	Q00987	MDM2	P48730	CSNK1D	S229	D223N	223	Missense	distal	-6	no	13.469	13.547	EPSD;PhosphoSitePlus	COSMIC	11.915	Up-regulation
CK1_CK1_CK1-D_CSNK1D_ST	Q00987	MDM2	P48730	CSNK1D	S229	V228L	228	Missense	proximal	-1	no	13.469	13.319	EPSD;PhosphoSitePlus	COSMIC	11.915	Down-regulation
CK1_CK1_CK1-D_CSNK1D_ST	Q00987	MDM2	P48730	CSNK1D	S229	D225N	225	Missense	distal	-4	no	13.469	13.463	EPSD;PhosphoSitePlus	COSMIC	11.915	Down-regulation
CK1_CK1_CK1-D_CSNK1D_ST	Q00987	MDM2	P48730	CSNK1D	S229	W235C	235	Missense	distal	6	no	13.469	9.366	EPSD;PhosphoSitePlus	COSMIC	11.915	Loss
CK1_CK1_CK1-D_CSNK1D_ST	Q00987	MDM2	P48730	CSNK1D	S229	V228A	228	Missense	proximal	-1	no	13.469	14.015	EPSD;PhosphoSitePlus	COSMIC	11.915	Up-regulation
CK1_CK1_CK1-D_CSNK1D_ST	Q00987	MDM2	P48730	CSNK1D	S229	V228I	228	Missense	proximal	-1	no	13.469	14.284	EPSD;PhosphoSitePlus	COSMIC	11.915	Up-regulation
CK1_CK1_CK1-D_CSNK1D_ST	Q00987	MDM2	P48730	CSNK1D	S240	W235C	235	Missense	distal	-5	no	17.704	20.484	EPSD;PhosphoSitePlus	COSMIC	11.915	Up-regulation
CK1_CK1_CK1-D_CSNK1D_ST	Q00987	MDM2	P48730	CSNK1D	S240	S240L	240	Missense	central	0	yes	17.704	0.000	EPSD;PhosphoSitePlus	COSMIC	11.915	Loss
CK1_CK1_CK1-D_CSNK1D_ST	Q00987	MDM2	P48730	CSNK1D	S240	D237H	237	Missense	distal	-3	no	17.704	15.765	EPSD;PhosphoSitePlus	COSMIC	11.915	Down-regulation
CK1_CK1_CK1-D_CSNK1D_ST	Q00987	MDM2	P48730	CSNK1D	S240	D239Y	239	Missense	proximal	-1	no	17.704	16.173	EPSD;PhosphoSitePlus	COSMIC	11.915	Down-regulation
CK1_CK1_CK1-D_CSNK1D_ST	Q00987	MDM2	P48730	CSNK1D	S240	D243H	243	Missense	distal	3	no	17.704	17.341	EPSD;PhosphoSitePlus	COSMIC	11.915	Down-regulation
CK1_CK1_CK1-D_CSNK1D_ST	Q00987	MDM2	P48730	CSNK1D	S242	W235C	235	Missense	distal	-7	no	14.165	14.656	EPSD	COSMIC	11.915	Up-regulation
CK1_CK1_CK1-D_CSNK1D_ST	Q00987	MDM2	P48730	CSNK1D	S242	S240L	240	Missense	proximal	-2	no	14.165	10.545	EPSD	COSMIC	11.915	Loss
CK1_CK1_CK1-D_CSNK1D_ST	Q00987	MDM2	P48730	CSNK1D	S242	D237H	237	Missense	distal	-5	no	14.165	12.193	EPSD	COSMIC	11.915	Down-regulation
CK1_CK1_CK1-D_CSNK1D_ST	Q00987	MDM2	P48730	CSNK1D	S242	D239Y	239	Missense	distal	-3	no	14.165	12.661	EPSD	COSMIC	11.915	Down-regulation
CK1_CK1_CK1-D_CSNK1D_ST	Q00987	MDM2	P48730	CSNK1D	S242	D243H	243	Missense	proximal	1	no	14.165	14.996	EPSD	COSMIC	11.915	Up-regulation
CK1_CK1_CK1-D_CSNK1D_ST	Q00987	MDM2	P48730	CSNK1D	S246	S253Y	253	Missense	distal	7	no	21.837	22.695	EPSD	COSMIC	11.915	Up-regulation
CK1_CK1_CK1-D_CSNK1D_ST	Q00987	MDM2	P48730	CSNK1D	S246	E252Q	252	Missense	distal	6	no	21.837	20.083	EPSD	COSMIC	11.915	Down-regulation
CK1_CK1_CK1-D_CSNK1D_ST	Q00987	MDM2	P48730	CSNK1D	S246	S240L	240	Missense	distal	-6	no	21.837	21.142	EPSD	COSMIC	11.915	Down-regulation
CK1_CK1_CK1-D_CSNK1D_ST	Q00987	MDM2	P48730	CSNK1D	S246	D239Y	239	Missense	distal	-7	no	21.837	19.532	EPSD	COSMIC	11.915	Down-regulation
CK1_CK1_CK1-D_CSNK1D_ST	Q00987	MDM2	P48730	CSNK1D	S246	D243H	243	Missense	distal	-3	no	21.837	19.898	EPSD	COSMIC	11.915	Down-regulation
CK1_CK1_CK1-D_CSNK1D_ST	Q00987	MDM2	P48730	CSNK1D	S253	E257K	257	Missense	distal	4	no	12.531	12.999	EPSD;PhosphoSitePlus	COSMIC	11.915	Up-regulation
CK1_CK1_CK1-D_CSNK1D_ST	Q00987	MDM2	P48730	CSNK1D	S253	S253Y	253	Missense	central	0	yes	12.531	0.000	EPSD;PhosphoSitePlus	COSMIC	11.915	Loss
CK1_CK1_CK1-D_CSNK1D_ST	Q00987	MDM2	P48730	CSNK1D	S253	E252Q	252	Missense	proximal	-1	no	12.531	11.746	EPSD;PhosphoSitePlus	COSMIC	11.915	Loss
CK1_CK1_CK1-D_CSNK1D_ST	Q00987	MDM2	P48730	CSNK1D	S253	D255N	255	Missense	proximal	2	no	12.531	12.008	EPSD;PhosphoSitePlus	COSMIC	11.915	Down-regulation
CK1_CK1_CK1-D_CSNK1D_ST	Q00987	MDM2	P48730	CSNK1D	S253	L254V	254	Missense	proximal	1	no	12.531	13.526	EPSD;PhosphoSitePlus	COSMIC	11.915	Up-regulation
CK1_CK1_CK1-D_CSNK1D_ST	Q00987	MDM2	P48730	CSNK1D	S260	L261R	261	Missense	proximal	1	no	12.807	11.876	EPSD;PhosphoSitePlus	COSMIC	11.915	Loss
CK1_CK1_CK1-D_CSNK1D_ST	Q00987	MDM2	P48730	CSNK1D	S260	E257K	257	Missense	distal	-3	no	12.807	10.160	EPSD;PhosphoSitePlus	COSMIC	11.915	Loss
CK1_CK1_CK1-D_CSNK1D_ST	Q00987	MDM2	P48730	CSNK1D	S260	S253Y	253	Missense	distal	-7	no	12.807	10.375	EPSD;PhosphoSitePlus	COSMIC	11.915	Loss
CK1_CK1_CK1-D_CSNK1D_ST	Q00987	MDM2	P48730	CSNK1D	S260	S262N	262	Missense	proximal	2	no	12.807	12.655	EPSD;PhosphoSitePlus	COSMIC	11.915	Down-regulation
CK1_CK1_CK1-D_CSNK1D_ST	Q00987	MDM2	P48730	CSNK1D	S260	D255N	255	Missense	distal	-5	no	12.807	14.493	EPSD;PhosphoSitePlus	COSMIC	11.915	Up-regulation
CK1_CK1_CK1-D_CSNK1D_ST	Q00987	MDM2	P48730	CSNK1D	S260	L254V	254	Missense	distal	-6	no	12.807	13.346	EPSD;PhosphoSitePlus	COSMIC	11.915	Up-regulation
CK1_CK1_CK1-D_CSNK1D_ST	Q00987	MDM2	P48730	CSNK1D	S260	G265E	265	Missense	distal	5	no	12.807	12.374	EPSD;PhosphoSitePlus	COSMIC	11.915	Down-regulation
CK1_CK1_CK1-D_CSNK1D_ST	Q00987	MDM2	P48730	CSNK1D	S260	E263K	263	Missense	distal	3	no	12.807	11.917	EPSD;PhosphoSitePlus	COSMIC	11.915	Down-regulation
CK1_CK1_CK1-D_CSNK1D_ST	Q00987	MDM2	P48730	CSNK1D	S262	L261R	261	Missense	proximal	-1	no	16.277	15.944	EPSD;PhosphoSitePlus	COSMIC	11.915	Down-regulation
CK1_CK1_CK1-D_CSNK1D_ST	Q00987	MDM2	P48730	CSNK1D	S262	E257K	257	Missense	distal	-5	no	16.277	14.700	EPSD;PhosphoSitePlus	COSMIC	11.915	Down-regulation
CK1_CK1_CK1-D_CSNK1D_ST	Q00987	MDM2	P48730	CSNK1D	S262	S262N	262	Missense	central	0	yes	16.277	0.000	EPSD;PhosphoSitePlus	COSMIC	11.915	Loss
CK1_CK1_CK1-D_CSNK1D_ST	Q00987	MDM2	P48730	CSNK1D	S262	D255N	255	Missense	distal	-7	no	16.277	17.141	EPSD;PhosphoSitePlus	COSMIC	11.915	Up-regulation
CK1_CK1_CK1-D_CSNK1D_ST	Q00987	MDM2	P48730	CSNK1D	S262	G265E	265	Missense	distal	3	no	16.277	16.721	EPSD;PhosphoSitePlus	COSMIC	11.915	Up-regulation
CK1_CK1_CK1-D_CSNK1D_ST	Q00987	MDM2	P48730	CSNK1D	S262	E263K	263	Missense	proximal	1	no	16.277	12.896	EPSD;PhosphoSitePlus	COSMIC	11.915	Down-regulation
CK1_CK1_CK1-D_CSNK1D_ST	Q00987	MDM2	P48730	CSNK1D	S269	D272N	272	Missense	distal	3	no	14.868	15.309	EPSD;PhosphoSitePlus	COSMIC	11.915	Up-regulation
CK1_CK1_CK1-D_CSNK1D_ST	Q00987	MDM2	P48730	CSNK1D	S269	Y276C	276	Missense	distal	7	no	14.868	12.621	EPSD;PhosphoSitePlus	COSMIC	11.915	Down-regulation
CK1_CK1_CK1-D_CSNK1D_ST	Q00987	MDM2	P48730	CSNK1D	S269	Y276H	276	Missense	distal	7	no	14.868	17.489	EPSD;PhosphoSitePlus	COSMIC	11.915	Up-regulation
CK1_CK1_CK1-D_CSNK1D_ST	Q00987	MDM2	P48730	CSNK1D	S269	S262N	262	Missense	distal	-7	no	14.868	15.605	EPSD;PhosphoSitePlus	COSMIC	11.915	Up-regulation
CK1_CK1_CK1-D_CSNK1D_ST	Q00987	MDM2	P48730	CSNK1D	S269	G265E	265	Missense	distal	-4	no	14.868	15.057	EPSD;PhosphoSitePlus	COSMIC	11.915	Up-regulation
CK1_CK1_CK1-D_CSNK1D_ST	Q00987	MDM2	P48730	CSNK1D	S269	E271D	271	Missense	proximal	2	no	14.868	14.722	EPSD;PhosphoSitePlus	COSMIC	11.915	Down-regulation
CK1_CK1_CK1-D_CSNK1D_ST	Q00987	MDM2	P48730	CSNK1D	S269	E263K	263	Missense	distal	-6	no	14.868	14.069	EPSD;PhosphoSitePlus	COSMIC	11.915	Down-regulation
CK1_CK1_CK1-D_CSNK1D_ST	Q00987	MDM2	P48730	CSNK1D	T279	G284W	284	Missense	distal	5	no	14.446	13.074	EPSD;PhosphoSitePlus	COSMIC	11.915	Down-regulation
CK1_CK1_CK1-D_CSNK1D_ST	Q00987	MDM2	P48730	CSNK1D	T279	D272N	272	Missense	distal	-7	no	14.446	15.310	EPSD;PhosphoSitePlus	COSMIC	11.915	Up-regulation
CK1_CK1_CK1-D_CSNK1D_ST	Q00987	MDM2	P48730	CSNK1D	T279	Y276C	276	Missense	distal	-3	no	14.446	13.893	EPSD;PhosphoSitePlus	COSMIC	11.915	Down-regulation
CK1_CK1_CK1-D_CSNK1D_ST	Q00987	MDM2	P48730	CSNK1D	T279	Y276H	276	Missense	distal	-3	no	14.446	14.012	EPSD;PhosphoSitePlus	COSMIC	11.915	Down-regulation
CK1_CK1_CK1-D_CSNK1D_ST	Q00987	MDM2	P48730	CSNK1D	T279	A283T	283	Missense	distal	4	no	14.446	14.894	EPSD;PhosphoSitePlus	COSMIC	11.915	Up-regulation
CK1_CK1_CK1-D_CSNK1D_ST	Q00987	MDM2	P48730	CSNK1D	T279	Y281H	281	Missense	proximal	2	no	14.446	15.265	EPSD;PhosphoSitePlus	COSMIC	11.915	Up-regulation
CK1_CK1_CK1-D_CSNK1D_ST	Q00987	MDM2	P48730	CSNK1D	T279	T279P	279	Missense	central	0	yes	14.446	0.000	EPSD;PhosphoSitePlus	COSMIC	11.915	Loss
CK1_CK1_CK1-D_CSNK1D_ST	Q00987	MDM2	P48730	CSNK1D	T279	V278D	278	Missense	proximal	-1	no	14.446	14.519	EPSD;PhosphoSitePlus	COSMIC	11.915	Up-regulation
CK1_CK1_CK1-D_CSNK1D_ST	Q00987	MDM2	P48730	CSNK1D	T279	E285K	285	Missense	distal	6	no	14.446	12.648	EPSD;PhosphoSitePlus	COSMIC	11.915	Down-regulation
CK1_CK1_CK1-D_CSNK1D_ST	Q00987	MDM2	P48730	CSNK1D	T279	V278A	278	Missense	proximal	-1	no	14.446	14.993	EPSD;PhosphoSitePlus	COSMIC	11.915	Up-regulation
CK1_CK1_CK1-D_CSNK1D_ST	Q00987	MDM2	P48730	CSNK1D	S286	G284W	284	Missense	proximal	-2	no	13.625	6.137	EPSD	COSMIC	11.915	Loss
CK1_CK1_CK1-D_CSNK1D_ST	Q00987	MDM2	P48730	CSNK1D	S286	A283T	283	Missense	distal	-3	no	13.625	14.477	EPSD	COSMIC	11.915	Up-regulation
CK1_CK1_CK1-D_CSNK1D_ST	Q00987	MDM2	P48730	CSNK1D	S286	Y281H	281	Missense	distal	-5	no	13.625	12.843	EPSD	COSMIC	11.915	Down-regulation
CK1_CK1_CK1-D_CSNK1D_ST	Q00987	MDM2	P48730	CSNK1D	S286	T279P	279	Missense	distal	-7	no	13.625	15.355	EPSD	COSMIC	11.915	Up-regulation
CK1_CK1_CK1-D_CSNK1D_ST	Q00987	MDM2	P48730	CSNK1D	S286	E285K	285	Missense	proximal	-1	no	13.625	12.839	EPSD	COSMIC	11.915	Down-regulation
CK1_CK1_CK1-D_CSNK1D_ST	Q00987	MDM2	P48730	CSNK1D	S286	D287N	287	Missense	proximal	1	no	13.625	12.317	EPSD	COSMIC	11.915	Down-regulation
CK1_CK1_CK1-D_CSNK1D_ST	Q00987	MDM2	P48730	CSNK1D	S286	F291S	291	Missense	distal	5	no	13.625	14.105	EPSD	COSMIC	11.915	Up-regulation
CK1_CK1_CK1-D_CSNK1D_ST	Q00987	MDM2	P48730	CSNK1D	S286	E292K	292	Missense	distal	6	no	13.625	11.826	EPSD	COSMIC	11.915	Loss
CK1_CK1_CK1-D_CSNK1D_ST	Q00987	MDM2	P48730	CSNK1D	S290	G284W	284	Missense	distal	-6	no	17.099	15.990	EPSD;PhosphoSitePlus	COSMIC	11.915	Down-regulation
CK1_CK1_CK1-D_CSNK1D_ST	Q00987	MDM2	P48730	CSNK1D	S290	A283T	283	Missense	distal	-7	no	17.099	15.378	EPSD;PhosphoSitePlus	COSMIC	11.915	Down-regulation
CK1_CK1_CK1-D_CSNK1D_ST	Q00987	MDM2	P48730	CSNK1D	S290	E285K	285	Missense	distal	-5	no	17.099	15.522	EPSD;PhosphoSitePlus	COSMIC	11.915	Down-regulation
CK1_CK1_CK1-D_CSNK1D_ST	Q00987	MDM2	P48730	CSNK1D	S290	E296D	296	Missense	distal	6	no	17.099	16.055	EPSD;PhosphoSitePlus	COSMIC	11.915	Down-regulation
CK1_CK1_CK1-D_CSNK1D_ST	Q00987	MDM2	P48730	CSNK1D	S290	D294Y	294	Missense	distal	4	no	17.099	17.305	EPSD;PhosphoSitePlus	COSMIC	11.915	Up-regulation
CK1_CK1_CK1-D_CSNK1D_ST	Q00987	MDM2	P48730	CSNK1D	S290	D287N	287	Missense	distal	-3	no	17.099	14.657	EPSD;PhosphoSitePlus	COSMIC	11.915	Down-regulation
CK1_CK1_CK1-D_CSNK1D_ST	Q00987	MDM2	P48730	CSNK1D	S290	F291S	291	Missense	proximal	1	no	17.099	15.708	EPSD;PhosphoSitePlus	COSMIC	11.915	Down-regulation
CK1_CK1_CK1-D_CSNK1D_ST	Q00987	MDM2	P48730	CSNK1D	S290	E292K	292	Missense	proximal	2	no	17.099	16.337	EPSD;PhosphoSitePlus	COSMIC	11.915	Down-regulation
CK1_CK1_CK1-D_CSNK1D_ST	Q00987	MDM2	P48730	CSNK1D	S290	I297M	297	Missense	distal	7	no	17.099	18.458	EPSD;PhosphoSitePlus	COSMIC	11.915	Up-regulation
CK1_CK1_CK1-D_CSNK1D_ST	Q00987	MDM2	P48730	CSNK1D	S342	E340D	340	Missense	proximal	-2	no	15.826	15.454	EPSD;PhosphoSitePlus	COSMIC	11.915	Down-regulation
CK1_CK1_CK1-D_CSNK1D_ST	Q00987	MDM2	P48730	CSNK1D	S342	D337N	337	Missense	distal	-5	no	15.826	17.512	EPSD;PhosphoSitePlus	COSMIC	11.915	Up-regulation
CK1_CK1_CK1-D_CSNK1D_ST	Q00987	MDM2	P48730	CSNK1D	S350	G356S	356	Missense	distal	6	no	22.545	24.016	EPSD;PhosphoSitePlus	COSMIC	11.915	Up-regulation
CK1_CK1_CK1-D_CSNK1D_ST	Q00987	MDM2	P48730	CSNK1D	S350	E355Q	355	Missense	distal	5	no	22.545	22.082	EPSD;PhosphoSitePlus	COSMIC	11.915	Down-regulation
CK1_CK1_CK1-D_CSNK1D_ST	Q00987	MDM2	P48730	CSNK1D	S350	E354K	354	Missense	distal	4	no	22.545	23.013	EPSD;PhosphoSitePlus	COSMIC	11.915	Up-regulation
CK1_CK1_CK1-D_CSNK1D_ST	Q00987	MDM2	P48730	CSNK1D	S350	E355K	355	Missense	distal	5	no	22.545	22.669	EPSD;PhosphoSitePlus	COSMIC	11.915	Up-regulation
CK1_CK1_CK1-D_CSNK1D_ST	Q00987	MDM2	P48730	CSNK1D	T351	G356S	356	Missense	distal	5	no	12.837	12.909	PhosphoSitePlus;EPSD	COSMIC	11.915	Up-regulation
CK1_CK1_CK1-D_CSNK1D_ST	Q00987	MDM2	P48730	CSNK1D	T351	E355Q	355	Missense	distal	4	no	12.837	13.351	PhosphoSitePlus;EPSD	COSMIC	11.915	Up-regulation
CK1_CK1_CK1-D_CSNK1D_ST	Q00987	MDM2	P48730	CSNK1D	T351	E354K	354	Missense	distal	3	no	12.837	11.948	PhosphoSitePlus;EPSD	COSMIC	11.915	Down-regulation
CK1_CK1_CK1-D_CSNK1D_ST	Q00987	MDM2	P48730	CSNK1D	T351	E355K	355	Missense	distal	4	no	12.837	13.305	PhosphoSitePlus;EPSD	COSMIC	11.915	Up-regulation
CK1_CK1_CK1-D_CSNK1D_ST	Q00987	MDM2	P48730	CSNK1D	T365	I366V	366	Missense	proximal	1	no	9.226	11.925	EPSD;PhosphoSitePlus	COSMIC	11.915	Gain
CK1_CK1_CK1-D_CSNK1D_ST	Q00987	MDM2	P48730	CSNK1D	S373	I366V	366	Missense	distal	-7	no	15.172	13.877	EPSD;PhosphoSitePlus	COSMIC	11.915	Down-regulation
CK1_CK1_CK1-D_CSNK1D_ST	Q00987	MDM2	P48730	CSNK1D	S373	E376D	376	Missense	distal	3	no	15.172	14.851	EPSD;PhosphoSitePlus	COSMIC	11.915	Down-regulation
CK1_CK1_CK1-D_CSNK1D_ST	Q00987	MDM2	P48730	CSNK1D	S373	D379G	379	Missense	distal	6	no	15.172	14.585	EPSD;PhosphoSitePlus	COSMIC	11.915	Down-regulation
CK1_CK1_CK1-D_CSNK1D_ST	Q00987	MDM2	P48730	CSNK1D	S386	Q384R	384	Missense	proximal	-2	no	17.010	15.527	EPSD;PhosphoSitePlus	COSMIC	11.915	Down-regulation
CK1_CK1_CK1-D_CSNK1D_ST	Q00987	MDM2	P48730	CSNK1D	S386	D393E	393	Missense	distal	7	no	17.010	16.623	EPSD;PhosphoSitePlus	COSMIC	11.915	Down-regulation
CK1_CK1_CK1-D_CSNK1D_ST	Q00987	MDM2	P48730	CSNK1D	S386	D393H	393	Missense	distal	7	no	17.010	19.420	EPSD;PhosphoSitePlus	COSMIC	11.915	Up-regulation
CK1_CK1_CK1-D_CSNK1D_ST	Q00987	MDM2	P48730	CSNK1D	S386	A385V	385	Missense	proximal	-1	no	17.010	16.464	EPSD;PhosphoSitePlus	COSMIC	11.915	Down-regulation
CK1_CK1_CK1-D_CSNK1D_ST	Q00987	MDM2	P48730	CSNK1D	S386	D379G	379	Missense	distal	-7	no	17.010	17.792	EPSD;PhosphoSitePlus	COSMIC	11.915	Up-regulation
CK1_CK1_CK1-D_CSNK1D_ST	Q00987	MDM2	P48730	CSNK1D	S395	D393E	393	Missense	proximal	-2	no	11.686	12.058	EPSD	COSMIC	11.915	Gain
CK1_CK1_CK1-D_CSNK1D_ST	Q00987	MDM2	P48730	CSNK1D	S395	D393H	393	Missense	proximal	-2	no	11.686	12.409	EPSD	COSMIC	11.915	Gain
CK1_CK1_CK1-D_CSNK1D_ST	Q00987	MDM2	P48730	CSNK1D	S407	Y405C	405	Missense	proximal	-2	no	7.258	11.956	EPSD	COSMIC	11.915	Gain
CK1_CK1_CK1-D_CSNK1D_ST	Q00987	MDM2	P48730	CSNK1D	T419	E413K	413	Missense	distal	-6	no	14.470	13.670	EPSD;PhosphoSitePlus	COSMIC	11.915	Down-regulation
CK1_CK1_CK1-D_CSNK1D_ST	Q00987	MDM2	P48730	CSNK1D	T419	E413G	413	Missense	distal	-6	no	14.470	13.563	EPSD;PhosphoSitePlus	COSMIC	11.915	Down-regulation
CK1_CK1_CK1-D_CSNK1D_ST	Q00987	MDM2	P48730	CSNK1D	T419	E415Q	415	Missense	distal	-4	no	14.470	14.369	EPSD;PhosphoSitePlus	COSMIC	11.915	Down-regulation
CK1_CK1_CK1-D_CSNK1D_ST	Q00987	MDM2	P48730	CSNK1D	T419	T419I	419	Missense	central	0	yes	14.470	0.000	EPSD;PhosphoSitePlus	COSMIC	11.915	Loss
CK1_CK1_CK1-D_CSNK1D_ST	Q00987	MDM2	P48730	CSNK1D	T419	S425C	425	Missense	distal	6	no	14.470	9.483	EPSD;PhosphoSitePlus	COSMIC	11.915	Loss
CK1_CK1_CK1-D_CSNK1D_ST	Q00987	MDM2	P48730	CSNK1D	T419	F414I	414	Missense	distal	-5	no	14.470	13.992	EPSD;PhosphoSitePlus	COSMIC	11.915	Down-regulation
CK1_CK1_CK1-D_CSNK1D_ST	Q00987	MDM2	P48730	CSNK1D	T419	V426A	426	Missense	distal	7	no	14.470	13.548	EPSD;PhosphoSitePlus	COSMIC	11.915	Down-regulation
CK1_CK1_CK1-D_CSNK1D_ST	Q00987	MDM2	P48730	CSNK1D	S425	T419I	419	Missense	distal	-6	no	13.778	13.935	EPSD	COSMIC	11.915	Up-regulation
CK1_CK1_CK1-D_CSNK1D_ST	Q00987	MDM2	P48730	CSNK1D	S425	S425C	425	Missense	central	0	yes	13.778	0.000	EPSD	COSMIC	11.915	Loss
CK1_CK1_CK1-D_CSNK1D_ST	Q00987	MDM2	P48730	CSNK1D	S425	S429R	429	Missense	distal	4	no	13.778	14.023	EPSD	COSMIC	11.915	Up-regulation
CK1_CK1_CK1-D_CSNK1D_ST	Q00987	MDM2	P48730	CSNK1D	S425	V426A	426	Missense	proximal	1	no	13.778	10.076	EPSD	COSMIC	11.915	Loss
CK1_CK1_CK1-D_CSNK1D_ST	P56817	BACE1	P48730	CSNK1D	S59	R57C	57	Missense	proximal	-2	no	10.607	12.299	EPSD	COSMIC	11.915	Gain
CK1_CK1_CK1-D_CSNK1D_ST	P56817	BACE1	P48730	CSNK1D	T292	P298S	298	Missense	distal	6	no	10.051	12.342	EPSD	COSMIC	11.915	Gain
CK1_CK1_CK1-D_CSNK1D_ST	P12830	CDH1	P48730	CSNK1D	T790	R796W	796	Missense	distal	6	no	10.369	12.396	EPSD	COSMIC	11.915	Gain
CK1_CK1_CK1-D_CSNK1D_ST	P12830	CDH1	P48730	CSNK1D	S838	G837E	837	Missense	proximal	-1	no	13.691	14.604	EPSD	COSMIC	11.915	Up-regulation
CK1_CK1_CK1-D_CSNK1D_ST	P12830	CDH1	P48730	CSNK1D	S838	D834H	834	Missense	distal	-4	no	13.691	13.456	EPSD	COSMIC	11.915	Down-regulation
CK1_CK1_CK1-D_CSNK1D_ST	P12830	CDH1	P48730	CSNK1D	S838	S838G	838	Missense	central	0	yes	13.691	0.000	EPSD	COSMIC	11.915	Loss
CK1_CK1_CK1-D_CSNK1D_ST	P12830	CDH1	P48730	CSNK1D	S838	F833Y	833	Missense	distal	-5	no	13.691	13.176	EPSD	COSMIC	11.915	Down-regulation
CK1_CK1_CK1-D_CSNK1D_ST	P12830	CDH1	P48730	CSNK1D	S838	S838I	838	Missense	central	0	yes	13.691	0.000	EPSD	COSMIC	11.915	Loss
CK1_CK1_CK1-D_CSNK1D_ST	P12830	CDH1	P48730	CSNK1D	S838	A842V	842	Missense	distal	4	no	13.691	14.942	EPSD	COSMIC	11.915	Up-regulation
CK1_CK1_CK1-D_CSNK1D_ST	P12830	CDH1	P48730	CSNK1D	S838	L845V	845	Missense	distal	7	no	13.691	13.268	EPSD	COSMIC	11.915	Down-regulation
CK1_CK1_CK1-D_CSNK1D_ST	P12830	CDH1	P48730	CSNK1D	S838	S840F	840	Missense	proximal	2	no	13.691	13.017	EPSD	COSMIC	11.915	Down-regulation
CK1_CK1_CK1-D_CSNK1D_ST	P12830	CDH1	P48730	CSNK1D	S840	G837E	837	Missense	distal	-3	no	15.917	16.018	EPSD	COSMIC	11.915	Up-regulation
CK1_CK1_CK1-D_CSNK1D_ST	P12830	CDH1	P48730	CSNK1D	S840	D834H	834	Missense	distal	-6	no	15.917	14.774	EPSD	COSMIC	11.915	Down-regulation
CK1_CK1_CK1-D_CSNK1D_ST	P12830	CDH1	P48730	CSNK1D	S840	S838G	838	Missense	proximal	-2	no	15.917	16.520	EPSD	COSMIC	11.915	Up-regulation
CK1_CK1_CK1-D_CSNK1D_ST	P12830	CDH1	P48730	CSNK1D	S840	F833Y	833	Missense	distal	-7	no	15.917	14.565	EPSD	COSMIC	11.915	Down-regulation
CK1_CK1_CK1-D_CSNK1D_ST	P12830	CDH1	P48730	CSNK1D	S840	S847F	847	Missense	distal	7	no	15.917	17.930	EPSD	COSMIC	11.915	Up-regulation
CK1_CK1_CK1-D_CSNK1D_ST	P12830	CDH1	P48730	CSNK1D	S840	S838I	838	Missense	proximal	-2	no	15.917	11.880	EPSD	COSMIC	11.915	Loss
CK1_CK1_CK1-D_CSNK1D_ST	P12830	CDH1	P48730	CSNK1D	S840	A842V	842	Missense	proximal	2	no	15.917	14.757	EPSD	COSMIC	11.915	Down-regulation
CK1_CK1_CK1-D_CSNK1D_ST	P12830	CDH1	P48730	CSNK1D	S840	S846T	846	Missense	distal	6	no	15.917	13.014	EPSD	COSMIC	11.915	Down-regulation
CK1_CK1_CK1-D_CSNK1D_ST	P12830	CDH1	P48730	CSNK1D	S840	L845V	845	Missense	distal	5	no	15.917	16.271	EPSD	COSMIC	11.915	Up-regulation
CK1_CK1_CK1-D_CSNK1D_ST	P12830	CDH1	P48730	CSNK1D	S840	S840F	840	Missense	central	0	yes	15.917	0.000	EPSD	COSMIC	11.915	Loss
CK1_CK1_CK1-D_CSNK1D_ST	P12830	CDH1	P48730	CSNK1D	S844	G837E	837	Missense	distal	-7	no	22.190	22.514	PhosphoSitePlus	COSMIC	11.915	Up-regulation
CK1_CK1_CK1-D_CSNK1D_ST	P12830	CDH1	P48730	CSNK1D	S844	S838G	838	Missense	distal	-6	no	22.190	21.542	PhosphoSitePlus	COSMIC	11.915	Down-regulation
CK1_CK1_CK1-D_CSNK1D_ST	P12830	CDH1	P48730	CSNK1D	S844	S847F	847	Missense	distal	3	no	22.190	21.031	PhosphoSitePlus	COSMIC	11.915	Down-regulation
CK1_CK1_CK1-D_CSNK1D_ST	P12830	CDH1	P48730	CSNK1D	S844	S838I	838	Missense	distal	-6	no	22.190	21.131	PhosphoSitePlus	COSMIC	11.915	Down-regulation
CK1_CK1_CK1-D_CSNK1D_ST	P12830	CDH1	P48730	CSNK1D	S844	A842V	842	Missense	proximal	-2	no	22.190	19.490	PhosphoSitePlus	COSMIC	11.915	Down-regulation
CK1_CK1_CK1-D_CSNK1D_ST	P12830	CDH1	P48730	CSNK1D	S844	S846T	846	Missense	proximal	2	no	22.190	21.418	PhosphoSitePlus	COSMIC	11.915	Down-regulation
CK1_CK1_CK1-D_CSNK1D_ST	P12830	CDH1	P48730	CSNK1D	S844	L845V	845	Missense	proximal	1	no	22.190	23.185	PhosphoSitePlus	COSMIC	11.915	Up-regulation
CK1_CK1_CK1-D_CSNK1D_ST	P12830	CDH1	P48730	CSNK1D	S844	S840F	840	Missense	distal	-4	no	22.190	21.860	PhosphoSitePlus	COSMIC	11.915	Down-regulation
CK1_CK1_CK1-D_CSNK1D_ST	P12830	CDH1	P48730	CSNK1D	S844	S851L	851	Missense	distal	7	no	22.190	23.996	PhosphoSitePlus	COSMIC	11.915	Up-regulation
CK1_CK1_CK1-D_CSNK1D_ST	P25054	APC	P48730	CSNK1D	S5	A4S	4	Missense	proximal	-1	no	12.628	11.818	EPSD	COSMIC	11.915	Loss
CK1_CK1_CK1-D_CSNK1D_ST	P25054	APC	P48730	CSNK1D	S5	D7N	7	Missense	proximal	2	no	12.628	12.105	EPSD	COSMIC	11.915	Down-regulation
CK1_CK1_CK1-D_CSNK1D_ST	P25054	APC	P48730	CSNK1D	S102	S95F	95	Missense	distal	-7	no	12.883	11.803	EPSD	COSMIC	11.915	Loss
CK1_CK1_CK1-D_CSNK1D_ST	P25054	APC	P48730	CSNK1D	S102	R99W	99	Missense	distal	-3	no	12.883	11.073	EPSD	COSMIC	11.915	Loss
CK1_CK1_CK1-D_CSNK1D_ST	P25054	APC	P48730	CSNK1D	S102	S105G	105	Missense	distal	3	no	12.883	11.961	EPSD	COSMIC	11.915	Down-regulation
CK1_CK1_CK1-D_CSNK1D_ST	P25054	APC	P48730	CSNK1D	S111	M115I	115	Missense	distal	4	no	17.073	16.719	EPSD	COSMIC	11.915	Down-regulation
CK1_CK1_CK1-D_CSNK1D_ST	P25054	APC	P48730	CSNK1D	S111	C110Y	110	Missense	proximal	-1	no	17.073	16.369	EPSD	COSMIC	11.915	Down-regulation
CK1_CK1_CK1-D_CSNK1D_ST	P25054	APC	P48730	CSNK1D	S111	S117L	117	Missense	distal	6	no	17.073	15.388	EPSD	COSMIC	11.915	Down-regulation
CK1_CK1_CK1-D_CSNK1D_ST	P25054	APC	P48730	CSNK1D	S111	S105G	105	Missense	distal	-6	no	17.073	16.425	EPSD	COSMIC	11.915	Down-regulation
CK1_CK1_CK1-D_CSNK1D_ST	P25054	APC	P48730	CSNK1D	S705	H712N	712	Missense	distal	7	no	12.044	9.366	EPSD	COSMIC	11.915	Loss
CK1_CK1_CK1-D_CSNK1D_ST	P25054	APC	P48730	CSNK1D	S705	A703V	703	Missense	proximal	-2	no	12.044	9.344	EPSD	COSMIC	11.915	Loss
CK1_CK1_CK1-D_CSNK1D_ST	P25054	APC	P48730	CSNK1D	S705	S705C	705	Missense	central	0	yes	12.044	0.000	EPSD	COSMIC	11.915	Loss
CK1_CK1_CK1-D_CSNK1D_ST	P25054	APC	P48730	CSNK1D	S705	V704I	704	Missense	proximal	-1	no	12.044	12.859	EPSD	COSMIC	11.915	Up-regulation
CK1_CK1_CK1-D_CSNK1D_ST	P25054	APC	P48730	CSNK1D	S705	G702W	702	Missense	distal	-3	no	12.044	9.795	EPSD	COSMIC	11.915	Loss
CK1_CK1_CK1-D_CSNK1D_ST	P25054	APC	P48730	CSNK1D	S705	A703G	703	Missense	proximal	-2	no	12.044	11.380	EPSD	COSMIC	11.915	Loss
CK1_CK1_CK1-D_CSNK1D_ST	P25054	APC	P48730	CSNK1D	S705	D700Y	700	Missense	distal	-5	no	12.044	10.854	EPSD	COSMIC	11.915	Loss
CK1_CK1_CK1-D_CSNK1D_ST	P25054	APC	P48730	CSNK1D	S780	L779V	779	Missense	proximal	-1	no	12.201	12.351	EPSD	COSMIC	11.915	Up-regulation
CK1_CK1_CK1-D_CSNK1D_ST	P25054	APC	P48730	CSNK1D	S780	N778D	778	Missense	proximal	-2	no	12.201	14.534	EPSD	COSMIC	11.915	Up-regulation
CK1_CK1_CK1-D_CSNK1D_ST	P25054	APC	P48730	CSNK1D	S780	K782E	782	Missense	proximal	2	no	12.201	12.963	EPSD	COSMIC	11.915	Up-regulation
CK1_CK1_CK1-D_CSNK1D_ST	P25054	APC	P48730	CSNK1D	S780	D777Y	777	Missense	distal	-3	no	12.201	10.696	EPSD	COSMIC	11.915	Loss
CK1_CK1_CK1-D_CSNK1D_ST	P25054	APC	P48730	CSNK1D	S780	P781L	781	Missense	proximal	1	no	12.201	12.152	EPSD	COSMIC	11.915	Down-regulation
CK1_CK1_CK1-D_CSNK1D_ST	P25054	APC	P48730	CSNK1D	S780	N775S	775	Missense	distal	-5	no	12.201	10.504	EPSD	COSMIC	11.915	Loss
CK1_CK1_CK1-D_CSNK1D_ST	P25054	APC	P48730	CSNK1D	S780	L779S	779	Missense	proximal	-1	no	12.201	12.086	EPSD	COSMIC	11.915	Down-regulation
CK1_CK1_CK1-D_CSNK1D_ST	P25054	APC	P48730	CSNK1D	S780	H785D	785	Missense	distal	5	no	12.201	13.437	EPSD	COSMIC	11.915	Up-regulation
CK1_CK1_CK1-D_CSNK1D_ST	P25054	APC	P48730	CSNK1D	S846	L852S	852	Missense	distal	6	no	11.334	13.020	EPSD	COSMIC	11.915	Gain
CK1_CK1_CK1-D_CSNK1D_ST	P25054	APC	P48730	CSNK1D	S846	L852M	852	Missense	distal	6	no	11.334	13.905	EPSD	COSMIC	11.915	Gain
CK1_CK1_CK1-D_CSNK1D_ST	P25054	APC	P48730	CSNK1D	S874	K875R	875	Missense	proximal	1	no	9.881	12.057	EPSD	COSMIC	11.915	Gain
CK1_CK1_CK1-D_CSNK1D_ST	P25054	APC	P48730	CSNK1D	S874	I880F	880	Missense	distal	6	no	9.881	12.049	EPSD	COSMIC	11.915	Gain
CK1_CK1_CK1-D_CSNK1D_ST	P25054	APC	P48730	CSNK1D	S895	A896S	896	Missense	proximal	1	no	11.681	12.117	EPSD	COSMIC	11.915	Gain
CK1_CK1_CK1-D_CSNK1D_ST	P25054	APC	P48730	CSNK1D	S905	T909I	909	Missense	distal	4	no	12.169	11.821	EPSD	COSMIC	11.915	Loss
CK1_CK1_CK1-D_CSNK1D_ST	P25054	APC	P48730	CSNK1D	S905	H898Y	898	Missense	distal	-7	no	12.169	11.738	EPSD	COSMIC	11.915	Loss
CK1_CK1_CK1-D_CSNK1D_ST	P25054	APC	P48730	CSNK1D	S905	S905G	905	Missense	central	0	yes	12.169	0.000	EPSD	COSMIC	11.915	Loss
CK1_CK1_CK1-D_CSNK1D_ST	P25054	APC	P48730	CSNK1D	S905	T909A	909	Missense	distal	4	no	12.169	11.721	EPSD	COSMIC	11.915	Loss
CK1_CK1_CK1-D_CSNK1D_ST	P25054	APC	P48730	CSNK1D	S905	S908T	908	Missense	distal	3	no	12.169	10.633	EPSD	COSMIC	11.915	Loss
CK1_CK1_CK1-D_CSNK1D_ST	P25054	APC	P48730	CSNK1D	S905	T899I	899	Missense	distal	-6	no	12.169	12.327	EPSD	COSMIC	11.915	Up-regulation
CK1_CK1_CK1-D_CSNK1D_ST	P25054	APC	P48730	CSNK1D	S905	S906F	906	Missense	proximal	1	no	12.169	13.560	EPSD	COSMIC	11.915	Up-regulation
CK1_CK1_CK1-D_CSNK1D_ST	P25054	APC	P48730	CSNK1D	S905	L912V	912	Missense	distal	7	no	12.169	11.745	EPSD	COSMIC	11.915	Loss
CK1_CK1_CK1-D_CSNK1D_ST	P25054	APC	P48730	CSNK1D	S905	Q901R	901	Missense	distal	-4	no	12.169	11.865	EPSD	COSMIC	11.915	Loss
CK1_CK1_CK1-D_CSNK1D_ST	P25054	APC	P48730	CSNK1D	S905	T909P	909	Missense	distal	4	no	12.169	12.196	EPSD	COSMIC	11.915	Up-regulation
CK1_CK1_CK1-D_CSNK1D_ST	P25054	APC	P48730	CSNK1D	S905	E911G	911	Missense	distal	6	no	12.169	10.538	EPSD	COSMIC	11.915	Loss
CK1_CK1_CK1-D_CSNK1D_ST	P25054	APC	P48730	CSNK1D	S905	D903G	903	Missense	proximal	-2	no	12.169	12.061	EPSD	COSMIC	11.915	Down-regulation
CK1_CK1_CK1-D_CSNK1D_ST	P25054	APC	P48730	CSNK1D	T930	A927G	927	Missense	distal	-3	no	11.218	13.005	EPSD	COSMIC;GDSC;CCLE	11.915	Gain
CK1_CK1_CK1-D_CSNK1D_ST	P25054	APC	P48730	CSNK1D	S987	P981L	981	Missense	distal	-6	no	11.866	12.814	EPSD	COSMIC	11.915	Gain
CK1_CK1_CK1-D_CSNK1D_ST	P25054	APC	P48730	CSNK1D	S987	K993N	993	Missense	distal	6	no	11.866	13.061	EPSD	COSMIC;GDSC;CCLE	11.915	Gain
CK1_CK1_CK1-D_CSNK1D_ST	P25054	APC	P48730	CSNK1D	S1032	E1034D	1034	Missense	proximal	2	no	15.228	15.082	EPSD	COSMIC;GDSC;CCLE	11.915	Down-regulation
CK1_CK1_CK1-D_CSNK1D_ST	P25054	APC	P48730	CSNK1D	S1032	Y1027D	1027	Missense	distal	-5	no	15.228	16.418	EPSD	COSMIC	11.915	Up-regulation
CK1_CK1_CK1-D_CSNK1D_ST	P25054	APC	P48730	CSNK1D	S1032	N1026K	1026	Missense	distal	-6	no	15.228	15.038	EPSD	COSMIC	11.915	Down-regulation
CK1_CK1_CK1-D_CSNK1D_ST	P25054	APC	P48730	CSNK1D	S1032	D1033N	1033	Missense	proximal	1	no	15.228	13.920	EPSD	COSMIC	11.915	Down-regulation
CK1_CK1_CK1-D_CSNK1D_ST	P25054	APC	P48730	CSNK1D	S1032	I1025V	1025	Missense	distal	-7	no	15.228	13.933	EPSD	COSMIC	11.915	Down-regulation
CK1_CK1_CK1-D_CSNK1D_ST	P25054	APC	P48730	CSNK1D	S1032	I1025M	1025	Missense	distal	-7	no	15.228	15.337	EPSD	COSMIC	11.915	Up-regulation
CK1_CK1_CK1-D_CSNK1D_ST	P25054	APC	P48730	CSNK1D	S1032	K1030E	1030	Missense	proximal	-2	no	15.228	16.504	EPSD	COSMIC	11.915	Up-regulation
CK1_CK1_CK1-D_CSNK1D_ST	P25054	APC	P48730	CSNK1D	S1032	Y1027C	1027	Missense	distal	-5	no	15.228	15.818	EPSD	COSMIC	11.915	Up-regulation
CK1_CK1_CK1-D_CSNK1D_ST	P25054	APC	P48730	CSNK1D	S1081	D1083E	1083	Missense	proximal	2	no	12.862	13.008	EPSD	COSMIC	11.915	Up-regulation
CK1_CK1_CK1-D_CSNK1D_ST	P25054	APC	P48730	CSNK1D	S1081	T1074A	1074	Missense	distal	-7	no	12.862	14.583	EPSD	COSMIC	11.915	Up-regulation
CK1_CK1_CK1-D_CSNK1D_ST	P25054	APC	P48730	CSNK1D	S1081	T1074I	1074	Missense	distal	-7	no	12.862	13.801	EPSD	COSMIC	11.915	Up-regulation
CK1_CK1_CK1-D_CSNK1D_ST	P25054	APC	P48730	CSNK1D	S1081	D1084Y	1084	Missense	distal	3	no	12.862	9.832	EPSD	COSMIC	11.915	Loss
CK1_CK1_CK1-D_CSNK1D_ST	P25054	APC	P48730	CSNK1D	S1081	S1081I	1081	Missense	central	0	yes	12.862	0.000	EPSD	COSMIC	11.915	Loss
CK1_CK1_CK1-D_CSNK1D_ST	P25054	APC	P48730	CSNK1D	S1104	Y1102H	1102	Missense	proximal	-2	no	6.851	12.005	EPSD	COSMIC	11.915	Gain
CK1_CK1_CK1-D_CSNK1D_ST	P25054	APC	P48730	CSNK1D	S1128	V1125A	1125	Missense	distal	-3	no	14.298	15.104	EPSD	COSMIC;GDSC	11.915	Up-regulation
CK1_CK1_CK1-D_CSNK1D_ST	P25054	APC	P48730	CSNK1D	S1128	L1129S	1129	Missense	proximal	1	no	14.298	12.027	EPSD	COSMIC	11.915	Down-regulation
CK1_CK1_CK1-D_CSNK1D_ST	P25054	APC	P48730	CSNK1D	S1128	D1134Y	1134	Missense	distal	6	no	14.298	12.345	EPSD	COSMIC	11.915	Down-regulation
CK1_CK1_CK1-D_CSNK1D_ST	P25054	APC	P48730	CSNK1D	S1128	V1125L	1125	Missense	distal	-3	no	14.298	15.434	EPSD	COSMIC	11.915	Up-regulation
CK1_CK1_CK1-D_CSNK1D_ST	P25054	APC	P48730	CSNK1D	S1128	D1134H	1134	Missense	distal	6	no	14.298	13.528	EPSD	COSMIC	11.915	Down-regulation
CK1_CK1_CK1-D_CSNK1D_ST	P25054	APC	P48730	CSNK1D	S1128	D1134N	1134	Missense	distal	6	no	14.298	14.738	EPSD	COSMIC	11.915	Up-regulation
CK1_CK1_CK1-D_CSNK1D_ST	P25054	APC	P48730	CSNK1D	S1128	I1121S	1121	Missense	distal	-7	no	14.298	14.603	EPSD	COSMIC	11.915	Up-regulation
CK1_CK1_CK1-D_CSNK1D_ST	P25054	APC	P48730	CSNK1D	S1128	D1133H	1133	Missense	distal	5	no	14.298	13.062	EPSD	COSMIC	11.915	Down-regulation
CK1_CK1_CK1-D_CSNK1D_ST	P25054	APC	P48730	CSNK1D	T1220	P1221L	1221	Missense	proximal	1	no	12.367	12.318	EPSD	COSMIC	11.915	Down-regulation
CK1_CK1_CK1-D_CSNK1D_ST	P25054	APC	P48730	CSNK1D	T1220	S1219T	1219	Missense	proximal	-1	no	12.367	11.823	EPSD	COSMIC	11.915	Loss
CK1_CK1_CK1-D_CSNK1D_ST	P25054	APC	P48730	CSNK1D	T1220	P1221A	1221	Missense	proximal	1	no	12.367	9.612	EPSD	COSMIC	11.915	Loss
CK1_CK1_CK1-D_CSNK1D_ST	P25054	APC	P48730	CSNK1D	T1220	S1213L	1213	Missense	distal	-7	no	12.367	10.667	EPSD	COSMIC	11.915	Loss
CK1_CK1_CK1-D_CSNK1D_ST	P25054	APC	P48730	CSNK1D	T1220	S1223Y	1223	Missense	distal	3	no	12.367	8.538	EPSD	COSMIC	11.915	Loss
CK1_CK1_CK1-D_CSNK1D_ST	P25054	APC	P48730	CSNK1D	S1222	P1221L	1221	Missense	proximal	-1	no	15.401	15.695	EPSD	COSMIC	11.915	Up-regulation
CK1_CK1_CK1-D_CSNK1D_ST	P25054	APC	P48730	CSNK1D	S1222	S1219T	1219	Missense	distal	-3	no	15.401	13.718	EPSD	COSMIC	11.915	Down-regulation
CK1_CK1_CK1-D_CSNK1D_ST	P25054	APC	P48730	CSNK1D	S1222	P1221A	1221	Missense	proximal	-1	no	15.401	16.391	EPSD	COSMIC	11.915	Up-regulation
CK1_CK1_CK1-D_CSNK1D_ST	P25054	APC	P48730	CSNK1D	S1222	S1223Y	1223	Missense	proximal	1	no	15.401	15.509	EPSD	COSMIC	11.915	Up-regulation
CK1_CK1_CK1-D_CSNK1D_ST	P25054	APC	P48730	CSNK1D	T1301	I1307K	1307	Missense	distal	6	no	12.823	13.900	EPSD	COSMIC;GDSC	11.915	Up-regulation
CK1_CK1_CK1-D_CSNK1D_ST	P25054	APC	P48730	CSNK1D	T1301	N1300S	1300	Missense	proximal	-1	no	12.823	12.489	EPSD	COSMIC	11.915	Down-regulation
CK1_CK1_CK1-D_CSNK1D_ST	P25054	APC	P48730	CSNK1D	T1301	D1297E	1297	Missense	distal	-4	no	12.823	12.964	EPSD	COSMIC	11.915	Up-regulation
CK1_CK1_CK1-D_CSNK1D_ST	P25054	APC	P48730	CSNK1D	T1301	D1297A	1297	Missense	distal	-4	no	12.823	13.367	EPSD	COSMIC	11.915	Up-regulation
CK1_CK1_CK1-D_CSNK1D_ST	P25054	APC	P48730	CSNK1D	T1301	E1306K	1306	Missense	distal	5	no	12.823	12.947	EPSD	COSMIC	11.915	Up-regulation
CK1_CK1_CK1-D_CSNK1D_ST	P25054	APC	P48730	CSNK1D	T1301	A1305G	1305	Missense	distal	4	no	12.823	13.116	EPSD	COSMIC	11.915	Up-regulation
CK1_CK1_CK1-D_CSNK1D_ST	P25054	APC	P48730	CSNK1D	T1301	K1308E	1308	Missense	distal	7	no	12.823	12.582	EPSD	COSMIC	11.915	Down-regulation
CK1_CK1_CK1-D_CSNK1D_ST	P25054	APC	P48730	CSNK1D	T1301	A1305E	1305	Missense	distal	4	no	12.823	12.766	EPSD	COSMIC	11.915	Down-regulation
CK1_CK1_CK1-D_CSNK1D_ST	P25054	APC	P48730	CSNK1D	T1301	N1300K	1300	Missense	proximal	-1	no	12.823	12.556	EPSD	COSMIC	11.915	Down-regulation
CK1_CK1_CK1-D_CSNK1D_ST	P25054	APC	P48730	CSNK1D	T1301	A1296V	1296	Missense	distal	-5	no	12.823	13.317	EPSD	COSMIC	11.915	Up-regulation
CK1_CK1_CK1-D_CSNK1D_ST	P25054	APC	P48730	CSNK1D	S1315	K1308E	1308	Missense	distal	-7	no	10.149	12.082	EPSD	COSMIC	11.915	Gain
CK1_CK1_CK1-D_CSNK1D_ST	P25054	APC	P48730	CSNK1D	S1343	S1341R	1341	Missense	proximal	-2	no	11.943	11.228	EPSD	COSMIC	11.915	Loss
CK1_CK1_CK1-D_CSNK1D_ST	P25054	APC	P48730	CSNK1D	S1343	S1344F	1344	Missense	proximal	1	no	11.943	13.334	EPSD	COSMIC	11.915	Up-regulation
CK1_CK1_CK1-D_CSNK1D_ST	P25054	APC	P48730	CSNK1D	S1343	G1339A	1339	Missense	distal	-4	no	11.943	12.535	EPSD	COSMIC	11.915	Up-regulation
CK1_CK1_CK1-D_CSNK1D_ST	P25054	APC	P48730	CSNK1D	S1343	G1339D	1339	Missense	distal	-4	no	11.943	11.992	EPSD	COSMIC	11.915	Up-regulation
CK1_CK1_CK1-D_CSNK1D_ST	P25054	APC	P48730	CSNK1D	S1343	H1349Y	1349	Missense	distal	6	no	11.943	10.760	EPSD	COSMIC	11.915	Loss
CK1_CK1_CK1-D_CSNK1D_ST	P25054	APC	P48730	CSNK1D	S1343	R1348G	1348	Missense	distal	5	no	11.943	12.203	EPSD	COSMIC	11.915	Up-regulation
CK1_CK1_CK1-D_CSNK1D_ST	P25054	APC	P48730	CSNK1D	S1343	K1350R	1350	Missense	distal	7	no	11.943	11.545	EPSD	COSMIC	11.915	Loss
CK1_CK1_CK1-D_CSNK1D_ST	P25054	APC	P48730	CSNK1D	S1343	S1346P	1346	Missense	distal	3	no	11.943	9.175	EPSD	COSMIC	11.915	Loss
CK1_CK1_CK1-D_CSNK1D_ST	P25054	APC	P48730	CSNK1D	S1343	K1350T	1350	Missense	distal	7	no	11.943	13.273	EPSD	COSMIC	11.915	Up-regulation
CK1_CK1_CK1-D_CSNK1D_ST	P25054	APC	P48730	CSNK1D	S1343	G1339S	1339	Missense	distal	-4	no	11.943	12.235	EPSD	COSMIC	11.915	Up-regulation
CK1_CK1_CK1-D_CSNK1D_ST	P25054	APC	P48730	CSNK1D	S1343	R1336S	1336	Missense	distal	-7	no	11.943	13.101	EPSD	COSMIC	11.915	Up-regulation
CK1_CK1_CK1-D_CSNK1D_ST	P25054	APC	P48730	CSNK1D	S1343	R1336I	1336	Missense	distal	-7	no	11.943	12.795	EPSD	COSMIC	11.915	Up-regulation
CK1_CK1_CK1-D_CSNK1D_ST	P25054	APC	P48730	CSNK1D	S1360	K1363E	1363	Missense	distal	3	no	11.394	12.284	EPSD	COSMIC	11.915	Gain
CK1_CK1_CK1-D_CSNK1D_ST	P25054	APC	P48730	CSNK1D	S1360	Q1367H	1367	Missense	distal	7	no	11.394	13.077	EPSD	COSMIC	11.915	Gain
CK1_CK1_CK1-D_CSNK1D_ST	P25054	APC	P48730	CSNK1D	T1368	A1366G	1366	Missense	proximal	-2	no	14.760	14.097	EPSD	COSMIC	11.915	Down-regulation
CK1_CK1_CK1-D_CSNK1D_ST	P25054	APC	P48730	CSNK1D	T1368	P1361L	1361	Missense	distal	-7	no	14.760	12.576	EPSD	COSMIC	11.915	Down-regulation
CK1_CK1_CK1-D_CSNK1D_ST	P25054	APC	P48730	CSNK1D	T1368	S1362F	1362	Missense	distal	-6	no	14.760	14.031	EPSD	COSMIC	11.915	Down-regulation
CK1_CK1_CK1-D_CSNK1D_ST	P25054	APC	P48730	CSNK1D	T1368	P1373S	1373	Missense	distal	5	no	14.760	14.898	EPSD	COSMIC	11.915	Up-regulation
CK1_CK1_CK1-D_CSNK1D_ST	P25054	APC	P48730	CSNK1D	T1368	T1368I	1368	Missense	central	0	yes	14.760	0.000	EPSD	COSMIC	11.915	Loss
CK1_CK1_CK1-D_CSNK1D_ST	P25054	APC	P48730	CSNK1D	T1368	S1364R	1364	Missense	distal	-4	no	14.760	14.253	EPSD	COSMIC	11.915	Down-regulation
CK1_CK1_CK1-D_CSNK1D_ST	P25054	APC	P48730	CSNK1D	T1368	P1369H	1369	Missense	proximal	1	no	14.760	15.900	EPSD	COSMIC	11.915	Up-regulation
CK1_CK1_CK1-D_CSNK1D_ST	P25054	APC	P48730	CSNK1D	T1368	K1363I	1363	Missense	distal	-5	no	14.760	14.166	EPSD	COSMIC	11.915	Down-regulation
CK1_CK1_CK1-D_CSNK1D_ST	P25054	APC	P48730	CSNK1D	T1368	K1363E	1363	Missense	distal	-5	no	14.760	16.338	EPSD	COSMIC	11.915	Up-regulation
CK1_CK1_CK1-D_CSNK1D_ST	P25054	APC	P48730	CSNK1D	T1368	E1374K	1374	Missense	distal	6	no	14.760	12.962	EPSD	COSMIC	11.915	Down-regulation
CK1_CK1_CK1-D_CSNK1D_ST	P25054	APC	P48730	CSNK1D	T1368	Q1367R	1367	Missense	proximal	-1	no	14.760	14.474	EPSD	COSMIC	11.915	Down-regulation
CK1_CK1_CK1-D_CSNK1D_ST	P25054	APC	P48730	CSNK1D	T1368	H1375Y	1375	Missense	distal	7	no	14.760	12.139	EPSD	COSMIC	11.915	Down-regulation
CK1_CK1_CK1-D_CSNK1D_ST	P25054	APC	P48730	CSNK1D	T1368	Q1367H	1367	Missense	proximal	-1	no	14.760	13.294	EPSD	COSMIC	11.915	Down-regulation
CK1_CK1_CK1-D_CSNK1D_ST	P25054	APC	P48730	CSNK1D	T1368	P1373T	1373	Missense	distal	5	no	14.760	13.778	EPSD	COSMIC	11.915	Down-regulation
CK1_CK1_CK1-D_CSNK1D_ST	P25054	APC	P48730	CSNK1D	T1368	P1373L	1373	Missense	distal	5	no	14.760	13.640	EPSD	COSMIC	11.915	Down-regulation
CK1_CK1_CK1-D_CSNK1D_ST	P25054	APC	P48730	CSNK1D	T1368	G1365D	1365	Missense	distal	-3	no	14.760	15.742	EPSD	COSMIC	11.915	Up-regulation
CK1_CK1_CK1-D_CSNK1D_ST	P25054	APC	P48730	CSNK1D	T1368	T1368K	1368	Missense	central	0	yes	14.760	0.000	EPSD	COSMIC	11.915	Loss
CK1_CK1_CK1-D_CSNK1D_ST	P25054	APC	P48730	CSNK1D	S1371	P1369H	1369	Missense	proximal	-2	no	9.985	12.307	EPSD	COSMIC	11.915	Gain
CK1_CK1_CK1-D_CSNK1D_ST	P25054	APC	P48730	CSNK1D	S1389	R1386S	1386	Missense	distal	-3	no	11.322	12.509	EPSD	COSMIC	11.915	Gain
CK1_CK1_CK1-D_CSNK1D_ST	P25054	APC	P48730	CSNK1D	S1389	L1382F	1382	Missense	distal	-7	no	11.322	11.941	EPSD	COSMIC	11.915	Gain
CK1_CK1_CK1-D_CSNK1D_ST	P25054	APC	P48730	CSNK1D	S1389	L1382P	1382	Missense	distal	-7	no	11.322	13.506	EPSD	COSMIC	11.915	Gain
CK1_CK1_CK1-D_CSNK1D_ST	P25054	APC	P48730	CSNK1D	S1504	A1508V	1508	Missense	distal	4	no	10.743	11.994	EPSD;PhosphoSitePlus	COSMIC	11.915	Gain
CK1_CK1_CK1-D_CSNK1D_ST	P25054	APC	P48730	CSNK1D	S1505	S1501A	1501	Missense	distal	-4	no	14.387	14.688	EPSD;PhosphoSitePlus	COSMIC	11.915	Up-regulation
CK1_CK1_CK1-D_CSNK1D_ST	P25054	APC	P48730	CSNK1D	S1505	G1499R	1499	Missense	distal	-6	no	14.387	14.805	EPSD;PhosphoSitePlus	COSMIC	11.915	Up-regulation
CK1_CK1_CK1-D_CSNK1D_ST	P25054	APC	P48730	CSNK1D	S1505	D1512N	1512	Missense	distal	7	no	14.387	14.119	EPSD;PhosphoSitePlus	COSMIC	11.915	Down-regulation
CK1_CK1_CK1-D_CSNK1D_ST	P25054	APC	P48730	CSNK1D	S1505	D1498N	1498	Missense	distal	-7	no	14.387	15.251	EPSD;PhosphoSitePlus	COSMIC	11.915	Up-regulation
CK1_CK1_CK1-D_CSNK1D_ST	P25054	APC	P48730	CSNK1D	S1505	S1504F	1504	Missense	proximal	-1	no	14.387	14.899	EPSD;PhosphoSitePlus	COSMIC	11.915	Up-regulation
CK1_CK1_CK1-D_CSNK1D_ST	P25054	APC	P48730	CSNK1D	S1505	A1508V	1508	Missense	distal	3	no	14.387	11.209	EPSD;PhosphoSitePlus	COSMIC	11.915	Loss
CK1_CK1_CK1-D_CSNK1D_ST	P25054	APC	P48730	CSNK1D	S1505	S1503L	1503	Missense	proximal	-2	no	14.387	10.766	EPSD;PhosphoSitePlus	COSMIC	11.915	Loss
CK1_CK1_CK1-D_CSNK1D_ST	P25054	APC	P48730	CSNK1D	S1505	S1501F	1501	Missense	distal	-4	no	14.387	14.056	EPSD;PhosphoSitePlus	COSMIC	11.915	Down-regulation
CK1_CK1_CK1-D_CSNK1D_ST	P25054	APC	P48730	CSNK1D	S1505	D1512V	1512	Missense	distal	7	no	14.387	14.699	EPSD;PhosphoSitePlus	COSMIC	11.915	Up-regulation
CK1_CK1_CK1-D_CSNK1D_ST	P25054	APC	P48730	CSNK1D	S1539	T1537K	1537	Missense	proximal	-2	no	13.822	12.021	EPSD	COSMIC	11.915	Down-regulation
CK1_CK1_CK1-D_CSNK1D_ST	P25054	APC	P48730	CSNK1D	S1539	E1536K	1536	Missense	distal	-3	no	13.822	11.175	EPSD	COSMIC	11.915	Loss
CK1_CK1_CK1-D_CSNK1D_ST	P25054	APC	P48730	CSNK1D	S1539	S1545L	1545	Missense	distal	6	no	13.822	12.137	EPSD	COSMIC;GDSC;CCLE	11.915	Down-regulation
CK1_CK1_CK1-D_CSNK1D_ST	P25054	APC	P48730	CSNK1D	S1539	G1534V	1534	Missense	distal	-5	no	13.822	14.526	EPSD	COSMIC	11.915	Up-regulation
CK1_CK1_CK1-D_CSNK1D_ST	P25054	APC	P48730	CSNK1D	S1539	G1534R	1534	Missense	distal	-5	no	13.822	13.495	EPSD	COSMIC	11.915	Down-regulation
CK1_CK1_CK1-D_CSNK1D_ST	P25054	APC	P48730	CSNK1D	S1539	G1534E	1534	Missense	distal	-5	no	13.822	14.636	EPSD	COSMIC	11.915	Up-regulation
CK1_CK1_CK1-D_CSNK1D_ST	P25054	APC	P48730	CSNK1D	S1539	N1533D	1533	Missense	distal	-6	no	13.822	13.743	EPSD	COSMIC	11.915	Down-regulation
CK1_CK1_CK1-D_CSNK1D_ST	P25054	APC	P48730	CSNK1D	S1539	E1544K	1544	Missense	distal	5	no	13.822	13.946	EPSD	COSMIC	11.915	Up-regulation
CK1_CK1_CK1-D_CSNK1D_ST	P25054	APC	P48730	CSNK1D	T1556	D1558N	1558	Missense	proximal	2	no	12.380	11.857	EPSD	COSMIC	11.915	Loss
CK1_CK1_CK1-D_CSNK1D_ST	P25054	APC	P48730	CSNK1D	T1556	A1553T	1553	Missense	distal	-3	no	12.380	13.232	EPSD	COSMIC	11.915	Up-regulation
CK1_CK1_CK1-D_CSNK1D_ST	P25054	APC	P48730	CSNK1D	T1556	D1562G	1562	Missense	distal	6	no	12.380	11.793	EPSD	COSMIC	11.915	Loss
CK1_CK1_CK1-D_CSNK1D_ST	P25054	APC	P48730	CSNK1D	T1556	K1561N	1561	Missense	distal	5	no	12.380	12.663	EPSD	COSMIC;GDSC;CCLE	11.915	Up-regulation
CK1_CK1_CK1-D_CSNK1D_ST	P25054	APC	P48730	CSNK1D	T1556	E1550K	1550	Missense	distal	-6	no	12.380	11.581	EPSD	COSMIC	11.915	Loss
CK1_CK1_CK1-D_CSNK1D_ST	P25054	APC	P48730	CSNK1D	T1556	A1553G	1553	Missense	distal	-3	no	12.380	14.166	EPSD	COSMIC	11.915	Up-regulation
CK1_CK1_CK1-D_CSNK1D_ST	P25054	APC	P48730	CSNK1D	S1757	A1759E	1759	Missense	proximal	2	no	12.417	12.201	EPSD	COSMIC	11.915	Down-regulation
CK1_CK1_CK1-D_CSNK1D_ST	P25054	APC	P48730	CSNK1D	S1757	P1760R	1760	Missense	distal	3	no	12.417	11.942	EPSD	COSMIC	11.915	Down-regulation
CK1_CK1_CK1-D_CSNK1D_ST	P25054	APC	P48730	CSNK1D	S1757	S1756C	1756	Missense	proximal	-1	no	12.417	11.928	EPSD	COSMIC	11.915	Down-regulation
CK1_CK1_CK1-D_CSNK1D_ST	P25054	APC	P48730	CSNK1D	S1837	P1843S	1843	Missense	distal	6	no	9.958	12.250	EPSD	COSMIC	11.915	Gain
CK1_CK1_CK1-D_CSNK1D_ST	P25054	APC	P48730	CSNK1D	S1861	S1864Y	1864	Missense	distal	3	no	12.600	8.771	EPSD	COSMIC;GDSC;CCLE	11.915	Loss
CK1_CK1_CK1-D_CSNK1D_ST	P25054	APC	P48730	CSNK1D	S1861	R1858Q	1858	Missense	distal	-3	no	12.600	10.581	EPSD	COSMIC	11.915	Loss
CK1_CK1_CK1-D_CSNK1D_ST	P25054	APC	P48730	CSNK1D	S1861	F1867V	1867	Missense	distal	6	no	12.600	10.410	EPSD	COSMIC	11.915	Loss
CK1_CK1_CK1-D_CSNK1D_ST	P25054	APC	P48730	CSNK1D	S1861	S1864F	1864	Missense	distal	3	no	12.600	11.441	EPSD	COSMIC	11.915	Loss
CK1_CK1_CK1-D_CSNK1D_ST	P25054	APC	P48730	CSNK1D	S1861	S1861F	1861	Missense	central	0	yes	12.600	0.000	EPSD	COSMIC	11.915	Loss
CK1_CK1_CK1-D_CSNK1D_ST	P25054	APC	P48730	CSNK1D	S1861	S1857L	1857	Missense	distal	-4	no	12.600	12.333	EPSD	COSMIC;GDSC;CCLE	11.915	Down-regulation
CK1_CK1_CK1-D_CSNK1D_ST	P25054	APC	P48730	CSNK1D	S1861	D1868H	1868	Missense	distal	7	no	12.600	15.010	EPSD	COSMIC	11.915	Up-regulation
CK1_CK1_CK1-D_CSNK1D_ST	P25054	APC	P48730	CSNK1D	S1861	L1862F	1862	Missense	proximal	1	no	12.600	11.721	EPSD	COSMIC	11.915	Loss
CK1_CK1_CK1-D_CSNK1D_ST	P25054	APC	P48730	CSNK1D	S1861	L1865P	1865	Missense	distal	4	no	12.600	12.541	EPSD	COSMIC	11.915	Down-regulation
CK1_CK1_CK1-D_CSNK1D_ST	P25054	APC	P48730	CSNK1D	S1861	C1855R	1855	Missense	distal	-6	no	12.600	12.630	EPSD	COSMIC	11.915	Up-regulation
CK1_CK1_CK1-D_CSNK1D_ST	P25054	APC	P48730	CSNK1D	S1863	S1864Y	1864	Missense	proximal	1	no	12.254	12.362	EPSD	COSMIC;GDSC;CCLE	11.915	Up-regulation
CK1_CK1_CK1-D_CSNK1D_ST	P25054	APC	P48730	CSNK1D	S1863	R1858Q	1858	Missense	distal	-5	no	12.254	13.031	EPSD	COSMIC	11.915	Up-regulation
CK1_CK1_CK1-D_CSNK1D_ST	P25054	APC	P48730	CSNK1D	S1863	F1867V	1867	Missense	distal	4	no	12.254	12.912	EPSD	COSMIC	11.915	Up-regulation
CK1_CK1_CK1-D_CSNK1D_ST	P25054	APC	P48730	CSNK1D	S1863	S1864F	1864	Missense	proximal	1	no	12.254	13.645	EPSD	COSMIC	11.915	Up-regulation
CK1_CK1_CK1-D_CSNK1D_ST	P25054	APC	P48730	CSNK1D	S1863	D1869G	1869	Missense	distal	6	no	12.254	11.667	EPSD	COSMIC	11.915	Loss
CK1_CK1_CK1-D_CSNK1D_ST	P25054	APC	P48730	CSNK1D	S1863	S1861F	1861	Missense	proximal	-2	no	12.254	10.513	EPSD	COSMIC	11.915	Loss
CK1_CK1_CK1-D_CSNK1D_ST	P25054	APC	P48730	CSNK1D	S1863	S1857L	1857	Missense	distal	-6	no	12.254	11.559	EPSD	COSMIC;GDSC;CCLE	11.915	Loss
CK1_CK1_CK1-D_CSNK1D_ST	P25054	APC	P48730	CSNK1D	S1863	D1868H	1868	Missense	distal	5	no	12.254	11.018	EPSD	COSMIC	11.915	Loss
CK1_CK1_CK1-D_CSNK1D_ST	P25054	APC	P48730	CSNK1D	S1863	L1862F	1862	Missense	proximal	-1	no	12.254	12.651	EPSD	COSMIC	11.915	Up-regulation
CK1_CK1_CK1-D_CSNK1D_ST	P25054	APC	P48730	CSNK1D	S1863	L1865P	1865	Missense	proximal	2	no	12.254	13.158	EPSD	COSMIC	11.915	Up-regulation
CK1_CK1_CK1-D_CSNK1D_ST	P25054	APC	P48730	CSNK1D	S1864	D1871N	1871	Missense	distal	7	no	12.673	12.405	EPSD	COSMIC	11.915	Down-regulation
CK1_CK1_CK1-D_CSNK1D_ST	P25054	APC	P48730	CSNK1D	S1864	S1864Y	1864	Missense	central	0	yes	12.673	0.000	EPSD	COSMIC;GDSC;CCLE	11.915	Loss
CK1_CK1_CK1-D_CSNK1D_ST	P25054	APC	P48730	CSNK1D	S1864	R1858Q	1858	Missense	distal	-6	no	12.673	12.339	EPSD	COSMIC	11.915	Down-regulation
CK1_CK1_CK1-D_CSNK1D_ST	P25054	APC	P48730	CSNK1D	S1864	F1867V	1867	Missense	distal	3	no	12.673	10.332	EPSD	COSMIC	11.915	Loss
CK1_CK1_CK1-D_CSNK1D_ST	P25054	APC	P48730	CSNK1D	S1864	S1864F	1864	Missense	central	0	yes	12.673	0.000	EPSD	COSMIC	11.915	Loss
CK1_CK1_CK1-D_CSNK1D_ST	P25054	APC	P48730	CSNK1D	S1864	D1869G	1869	Missense	distal	5	no	12.673	13.129	EPSD	COSMIC	11.915	Up-regulation
CK1_CK1_CK1-D_CSNK1D_ST	P25054	APC	P48730	CSNK1D	S1864	S1861F	1861	Missense	distal	-3	no	12.673	10.586	EPSD	COSMIC	11.915	Loss
CK1_CK1_CK1-D_CSNK1D_ST	P25054	APC	P48730	CSNK1D	S1864	S1857L	1857	Missense	distal	-7	no	12.673	10.973	EPSD	COSMIC;GDSC;CCLE	11.915	Loss
CK1_CK1_CK1-D_CSNK1D_ST	P25054	APC	P48730	CSNK1D	S1864	D1868H	1868	Missense	distal	4	no	12.673	13.041	EPSD	COSMIC	11.915	Up-regulation
CK1_CK1_CK1-D_CSNK1D_ST	P25054	APC	P48730	CSNK1D	S1864	L1862F	1862	Missense	proximal	-2	no	12.673	14.552	EPSD	COSMIC	11.915	Up-regulation
CK1_CK1_CK1-D_CSNK1D_ST	P25054	APC	P48730	CSNK1D	S1864	L1865P	1865	Missense	proximal	1	no	12.673	12.721	EPSD	COSMIC	11.915	Up-regulation
CK1_CK1_CK1-D_CSNK1D_ST	P25054	APC	P48730	CSNK1D	S1896	N1903S	1903	Missense	distal	7	no	12.520	11.718	EPSD	COSMIC	11.915	Loss
CK1_CK1_CK1-D_CSNK1D_ST	P25054	APC	P48730	CSNK1D	S1896	S1890L	1890	Missense	distal	-6	no	12.520	11.826	EPSD	COSMIC;GDSC;CCLE	11.915	Loss
CK1_CK1_CK1-D_CSNK1D_ST	P25054	APC	P48730	CSNK1D	S1896	E1891K	1891	Missense	distal	-5	no	12.520	10.943	EPSD	COSMIC	11.915	Loss
CK1_CK1_CK1-D_CSNK1D_ST	P25054	APC	P48730	CSNK1D	S1896	H1897P	1897	Missense	proximal	1	no	12.520	11.380	EPSD	COSMIC	11.915	Loss
CK1_CK1_CK1-D_CSNK1D_ST	P25054	APC	P48730	CSNK1D	S1896	N1903Y	1903	Missense	distal	7	no	12.520	12.577	EPSD	COSMIC	11.915	Up-regulation
CK1_CK1_CK1-D_CSNK1D_ST	P25054	APC	P48730	CSNK1D	S1896	E1889G	1889	Missense	distal	-7	no	12.520	12.196	EPSD	COSMIC	11.915	Down-regulation
CK1_CK1_CK1-D_CSNK1D_ST	P25054	APC	P48730	CSNK1D	S2034	L2027P	2027	Missense	distal	-7	no	12.704	14.889	EPSD	COSMIC	11.915	Up-regulation
CK1_CK1_CK1-D_CSNK1D_ST	P25054	APC	P48730	CSNK1D	S2034	L2030I	2030	Missense	distal	-4	no	12.704	12.951	EPSD	COSMIC	11.915	Up-regulation
CK1_CK1_CK1-D_CSNK1D_ST	P25054	APC	P48730	CSNK1D	S2034	D2037H	2037	Missense	distal	3	no	12.704	12.342	EPSD	COSMIC	11.915	Down-regulation
CK1_CK1_CK1-D_CSNK1D_ST	P25054	APC	P48730	CSNK1D	S2064	P2065L	2065	Missense	proximal	1	no	13.639	13.591	EPSD	COSMIC	11.915	Down-regulation
CK1_CK1_CK1-D_CSNK1D_ST	P25054	APC	P48730	CSNK1D	S2064	R2066K	2066	Missense	proximal	2	no	13.639	13.629	EPSD	COSMIC	11.915	Down-regulation
CK1_CK1_CK1-D_CSNK1D_ST	P25054	APC	P48730	CSNK1D	S2064	N2060D	2060	Missense	distal	-4	no	13.639	13.645	EPSD	COSMIC	11.915	Up-regulation
CK1_CK1_CK1-D_CSNK1D_ST	P25054	APC	P48730	CSNK1D	S2064	M2068I	2068	Missense	distal	4	no	13.639	13.285	EPSD	COSMIC	11.915	Down-regulation
CK1_CK1_CK1-D_CSNK1D_ST	P25054	APC	P48730	CSNK1D	S2064	D2059N	2059	Missense	distal	-5	no	13.639	15.326	EPSD	COSMIC	11.915	Up-regulation
CK1_CK1_CK1-D_CSNK1D_ST	P25054	APC	P48730	CSNK1D	S2064	G2070A	2070	Missense	distal	6	no	13.639	13.470	EPSD	COSMIC	11.915	Down-regulation
CK1_CK1_CK1-D_CSNK1D_ST	P25054	APC	P48730	CSNK1D	S2064	G2070V	2070	Missense	distal	6	no	13.639	12.373	EPSD	COSMIC	11.915	Down-regulation
CK1_CK1_CK1-D_CSNK1D_ST	P25054	APC	P48730	CSNK1D	S2064	I2071T	2071	Missense	distal	7	no	13.639	15.666	EPSD	COSMIC	11.915	Up-regulation
CK1_CK1_CK1-D_CSNK1D_ST	P25054	APC	P48730	CSNK1D	S2064	N2067I	2067	Missense	distal	3	no	13.639	11.041	EPSD	COSMIC	11.915	Loss
CK1_CK1_CK1-D_CSNK1D_ST	P25054	APC	P48730	CSNK1D	S2064	K2057R	2057	Missense	distal	-7	no	13.639	13.436	EPSD	COSMIC	11.915	Down-regulation
CK1_CK1_CK1-D_CSNK1D_ST	P25054	APC	P48730	CSNK1D	S2093	F2099C	2099	Missense	distal	6	no	13.557	9.118	EPSD	COSMIC	11.915	Loss
CK1_CK1_CK1-D_CSNK1D_ST	P25054	APC	P48730	CSNK1D	S2093	P2094L	2094	Missense	proximal	1	no	13.557	13.508	EPSD	COSMIC	11.915	Down-regulation
CK1_CK1_CK1-D_CSNK1D_ST	P25054	APC	P48730	CSNK1D	S2093	N2098S	2098	Missense	distal	5	no	13.557	13.654	EPSD	COSMIC	11.915	Up-regulation
CK1_CK1_CK1-D_CSNK1D_ST	P25054	APC	P48730	CSNK1D	S2093	S2093Y	2093	Missense	central	0	yes	13.557	0.000	EPSD	COSMIC	11.915	Loss
CK1_CK1_CK1-D_CSNK1D_ST	P25054	APC	P48730	CSNK1D	S2093	L2092I	2092	Missense	proximal	-1	no	13.557	14.522	EPSD	COSMIC	11.915	Up-regulation
CK1_CK1_CK1-D_CSNK1D_ST	P25054	APC	P48730	CSNK1D	S2110	V2112I	2112	Missense	proximal	2	no	11.746	13.013	EPSD	COSMIC	11.915	Gain
CK1_CK1_CK1-D_CSNK1D_ST	P25054	APC	P48730	CSNK1D	S2110	A2108T	2108	Missense	proximal	-2	no	11.746	12.088	EPSD	COSMIC	11.915	Gain
CK1_CK1_CK1-D_CSNK1D_ST	P25054	APC	P48730	CSNK1D	S2125	S2125F	2125	Missense	central	0	yes	12.879	0.000	EPSD	COSMIC	11.915	Loss
CK1_CK1_CK1-D_CSNK1D_ST	P25054	APC	P48730	CSNK1D	S2125	S2129L	2129	Missense	distal	4	no	12.879	13.244	EPSD	COSMIC;GDSC	11.915	Up-regulation
CK1_CK1_CK1-D_CSNK1D_ST	P25054	APC	P48730	CSNK1D	S2125	R2126G	2126	Missense	proximal	1	no	12.879	14.699	EPSD	COSMIC	11.915	Up-regulation
CK1_CK1_CK1-D_CSNK1D_ST	P25054	APC	P48730	CSNK1D	S2125	D2131Y	2131	Missense	distal	6	no	12.879	10.926	EPSD	COSMIC	11.915	Loss
CK1_CK1_CK1-D_CSNK1D_ST	P25054	APC	P48730	CSNK1D	S2125	A2128V	2128	Missense	distal	3	no	12.879	9.701	EPSD	COSMIC	11.915	Loss
CK1_CK1_CK1-D_CSNK1D_ST	P25054	APC	P48730	CSNK1D	S2125	A2121V	2121	Missense	distal	-4	no	12.879	12.112	EPSD	COSMIC	11.915	Down-regulation
CK1_CK1_CK1-D_CSNK1D_ST	P25054	APC	P48730	CSNK1D	S2125	R2126S	2126	Missense	proximal	1	no	12.879	11.539	EPSD	COSMIC	11.915	Loss
CK1_CK1_CK1-D_CSNK1D_ST	P25054	APC	P48730	CSNK1D	S2129	S2125F	2125	Missense	distal	-4	no	12.464	12.133	EPSD	COSMIC	11.915	Down-regulation
CK1_CK1_CK1-D_CSNK1D_ST	P25054	APC	P48730	CSNK1D	S2129	S2129L	2129	Missense	central	0	yes	12.464	0.000	EPSD	COSMIC;GDSC	11.915	Loss
CK1_CK1_CK1-D_CSNK1D_ST	P25054	APC	P48730	CSNK1D	S2129	R2126G	2126	Missense	distal	-3	no	12.464	12.903	EPSD	COSMIC	11.915	Up-regulation
CK1_CK1_CK1-D_CSNK1D_ST	P25054	APC	P48730	CSNK1D	S2129	D2131Y	2131	Missense	proximal	2	no	12.464	10.192	EPSD	COSMIC	11.915	Loss
CK1_CK1_CK1-D_CSNK1D_ST	P25054	APC	P48730	CSNK1D	S2129	S2134C	2134	Missense	distal	5	no	12.464	12.820	EPSD	COSMIC;GDSC;CCLE	11.915	Up-regulation
CK1_CK1_CK1-D_CSNK1D_ST	P25054	APC	P48730	CSNK1D	S2129	L2136F	2136	Missense	distal	7	no	12.464	12.671	EPSD	COSMIC	11.915	Up-regulation
CK1_CK1_CK1-D_CSNK1D_ST	P25054	APC	P48730	CSNK1D	S2129	A2128V	2128	Missense	proximal	-1	no	12.464	11.917	EPSD	COSMIC	11.915	Down-regulation
CK1_CK1_CK1-D_CSNK1D_ST	P25054	APC	P48730	CSNK1D	S2129	R2126S	2126	Missense	distal	-3	no	12.464	13.652	EPSD	COSMIC	11.915	Up-regulation
CK1_CK1_CK1-D_CSNK1D_ST	P25054	APC	P48730	CSNK1D	S2132	S2125F	2125	Missense	distal	-7	no	13.042	11.962	EPSD	COSMIC	11.915	Down-regulation
CK1_CK1_CK1-D_CSNK1D_ST	P25054	APC	P48730	CSNK1D	S2132	S2129L	2129	Missense	distal	-3	no	13.042	10.837	EPSD	COSMIC;GDSC	11.915	Loss
CK1_CK1_CK1-D_CSNK1D_ST	P25054	APC	P48730	CSNK1D	S2132	R2126G	2126	Missense	distal	-6	no	13.042	12.623	EPSD	COSMIC	11.915	Down-regulation
CK1_CK1_CK1-D_CSNK1D_ST	P25054	APC	P48730	CSNK1D	S2132	D2131Y	2131	Missense	proximal	-1	no	13.042	11.512	EPSD	COSMIC	11.915	Loss
CK1_CK1_CK1-D_CSNK1D_ST	P25054	APC	P48730	CSNK1D	S2132	S2134C	2134	Missense	proximal	2	no	13.042	12.207	EPSD	COSMIC;GDSC;CCLE	11.915	Down-regulation
CK1_CK1_CK1-D_CSNK1D_ST	P25054	APC	P48730	CSNK1D	S2132	S2137F	2137	Missense	distal	5	no	13.042	12.562	EPSD	COSMIC	11.915	Down-regulation
CK1_CK1_CK1-D_CSNK1D_ST	P25054	APC	P48730	CSNK1D	S2132	L2136F	2136	Missense	distal	4	no	13.042	13.101	EPSD	COSMIC	11.915	Up-regulation
CK1_CK1_CK1-D_CSNK1D_ST	P25054	APC	P48730	CSNK1D	S2132	A2128V	2128	Missense	distal	-4	no	13.042	12.275	EPSD	COSMIC	11.915	Down-regulation
CK1_CK1_CK1-D_CSNK1D_ST	P25054	APC	P48730	CSNK1D	S2132	R2126S	2126	Missense	distal	-6	no	13.042	13.272	EPSD	COSMIC	11.915	Up-regulation
CK1_CK1_CK1-D_CSNK1D_ST	P25054	APC	P48730	CSNK1D	S2143	H2149N	2149	Missense	distal	6	no	11.031	12.241	EPSD	COSMIC	11.915	Gain
CK1_CK1_CK1-D_CSNK1D_ST	P25054	APC	P48730	CSNK1D	S2207	M2213I	2213	Missense	distal	6	no	13.333	9.732	EPSD	COSMIC	11.915	Loss
CK1_CK1_CK1-D_CSNK1D_ST	P25054	APC	P48730	CSNK1D	S2207	S2205P	2205	Missense	proximal	-2	no	13.333	12.444	EPSD	COSMIC	11.915	Down-regulation
CK1_CK1_CK1-D_CSNK1D_ST	P25054	APC	P48730	CSNK1D	S2207	S2205Y	2205	Missense	proximal	-2	no	13.333	9.611	EPSD	COSMIC	11.915	Loss
CK1_CK1_CK1-D_CSNK1D_ST	P25054	APC	P48730	CSNK1D	S2207	M2213V	2213	Missense	distal	6	no	13.333	9.710	EPSD	COSMIC	11.915	Loss
CK1_CK1_CK1-D_CSNK1D_ST	P25054	APC	P48730	CSNK1D	S2207	K2202E	2202	Missense	distal	-5	no	13.333	14.910	EPSD	COSMIC	11.915	Up-regulation
CK1_CK1_CK1-D_CSNK1D_ST	P25054	APC	P48730	CSNK1D	S2244	S2241L	2241	Missense	distal	-3	no	13.176	10.971	EPSD	COSMIC	11.915	Loss
CK1_CK1_CK1-D_CSNK1D_ST	P25054	APC	P48730	CSNK1D	S2244	V2246I	2246	Missense	proximal	2	no	13.176	14.443	EPSD	COSMIC	11.915	Up-regulation
CK1_CK1_CK1-D_CSNK1D_ST	P25054	APC	P48730	CSNK1D	S2244	S2247P	2247	Missense	distal	3	no	13.176	10.407	EPSD	COSMIC	11.915	Loss
CK1_CK1_CK1-D_CSNK1D_ST	P25054	APC	P48730	CSNK1D	S2244	R2237L	2237	Missense	distal	-7	no	13.176	12.634	EPSD	COSMIC	11.915	Down-regulation
CK1_CK1_CK1-D_CSNK1D_ST	P25054	APC	P48730	CSNK1D	S2244	S2242G	2242	Missense	proximal	-2	no	13.176	13.779	EPSD	COSMIC	11.915	Up-regulation
CK1_CK1_CK1-D_CSNK1D_ST	P25054	APC	P48730	CSNK1D	S2244	K2249Q	2249	Missense	distal	5	no	13.176	12.589	EPSD	COSMIC	11.915	Down-regulation
CK1_CK1_CK1-D_CSNK1D_ST	P25054	APC	P48730	CSNK1D	S2290	S2296N	2296	Missense	distal	6	no	12.000	11.556	EPSD	COSMIC	11.915	Loss
CK1_CK1_CK1-D_CSNK1D_ST	P25054	APC	P48730	CSNK1D	S2290	K2297E	2297	Missense	distal	7	no	12.000	11.758	EPSD	COSMIC	11.915	Loss
CK1_CK1_CK1-D_CSNK1D_ST	P25054	APC	P48730	CSNK1D	S2290	V2285A	2285	Missense	distal	-5	no	12.000	11.506	EPSD	COSMIC	11.915	Loss
CK1_CK1_CK1-D_CSNK1D_ST	P25054	APC	P48730	CSNK1D	S2290	G2294R	2294	Missense	distal	4	no	12.000	12.122	EPSD	COSMIC	11.915	Up-regulation
CK1_CK1_CK1-D_CSNK1D_ST	P25054	APC	P48730	CSNK1D	S2290	S2295L	2295	Missense	distal	5	no	12.000	10.741	EPSD	COSMIC	11.915	Loss
CK1_CK1_CK1-D_CSNK1D_ST	P25054	APC	P48730	CSNK1D	S2290	A2286S	2286	Missense	distal	-4	no	12.000	11.699	EPSD	COSMIC	11.915	Loss
CK1_CK1_CK1-D_CSNK1D_ST	P25054	APC	P48730	CSNK1D	S2290	V2285I	2285	Missense	distal	-5	no	12.000	9.937	EPSD	COSMIC	11.915	Loss
CK1_CK1_CK1-D_CSNK1D_ST	P25054	APC	P48730	CSNK1D	S2290	G2293C	2293	Missense	distal	3	no	12.000	9.910	EPSD	COSMIC	11.915	Loss
CK1_CK1_CK1-D_CSNK1D_ST	P25054	APC	P48730	CSNK1D	S2290	P2284S	2284	Missense	distal	-6	no	12.000	13.642	EPSD	COSMIC	11.915	Up-regulation
CK1_CK1_CK1-D_CSNK1D_ST	P25054	APC	P48730	CSNK1D	S2307	G2303R	2303	Missense	distal	-4	no	12.844	12.627	EPSD	COSMIC	11.915	Down-regulation
CK1_CK1_CK1-D_CSNK1D_ST	P25054	APC	P48730	CSNK1D	S2307	S2302L	2302	Missense	distal	-5	no	12.844	11.204	EPSD	COSMIC	11.915	Loss
CK1_CK1_CK1-D_CSNK1D_ST	P25054	APC	P48730	CSNK1D	S2307	A2313T	2313	Missense	distal	6	no	12.844	11.582	EPSD	COSMIC	11.915	Loss
CK1_CK1_CK1-D_CSNK1D_ST	P25054	APC	P48730	CSNK1D	S2307	P2309L	2309	Missense	proximal	2	no	12.844	11.939	EPSD	COSMIC	11.915	Down-regulation
CK1_CK1_CK1-D_CSNK1D_ST	P25054	APC	P48730	CSNK1D	S2307	R2311T	2311	Missense	distal	4	no	12.844	12.876	EPSD	COSMIC	11.915	Up-regulation
CK1_CK1_CK1-D_CSNK1D_ST	P25054	APC	P48730	CSNK1D	S2310	S2307T	2307	Missense	distal	-3	no	13.717	12.034	EPSD	COSMIC	11.915	Down-regulation
CK1_CK1_CK1-D_CSNK1D_ST	P25054	APC	P48730	CSNK1D	S2310	G2303R	2303	Missense	distal	-7	no	13.717	11.904	EPSD	COSMIC	11.915	Loss
CK1_CK1_CK1-D_CSNK1D_ST	P25054	APC	P48730	CSNK1D	S2310	A2313T	2313	Missense	distal	3	no	13.717	12.502	EPSD	COSMIC	11.915	Down-regulation
CK1_CK1_CK1-D_CSNK1D_ST	P25054	APC	P48730	CSNK1D	S2310	P2309L	2309	Missense	proximal	-1	no	13.717	14.011	EPSD	COSMIC	11.915	Up-regulation
CK1_CK1_CK1-D_CSNK1D_ST	P25054	APC	P48730	CSNK1D	S2310	R2311T	2311	Missense	proximal	1	no	13.717	13.522	EPSD	COSMIC	11.915	Down-regulation
CK1_CK1_CK1-D_CSNK1D_ST	P25054	APC	P48730	CSNK1D	S2310	P2316L	2316	Missense	distal	6	no	13.717	14.323	EPSD	COSMIC	11.915	Up-regulation
CK1_CK1_CK1-D_CSNK1D_ST	P25054	APC	P48730	CSNK1D	S2337	K2341N	2341	Missense	distal	4	no	13.073	12.527	EPSD	COSMIC	11.915	Down-regulation
CK1_CK1_CK1-D_CSNK1D_ST	P25054	APC	P48730	CSNK1D	S2337	Q2344E	2344	Missense	distal	7	no	13.073	11.959	EPSD	COSMIC	11.915	Down-regulation
CK1_CK1_CK1-D_CSNK1D_ST	P25054	APC	P48730	CSNK1D	S2359	S2355L	2355	Missense	distal	-4	no	14.602	14.335	EPSD	COSMIC	11.915	Down-regulation
CK1_CK1_CK1-D_CSNK1D_ST	P25054	APC	P48730	CSNK1D	S2359	T2356I	2356	Missense	distal	-3	no	14.602	8.213	EPSD	COSMIC	11.915	Loss
CK1_CK1_CK1-D_CSNK1D_ST	P25054	APC	P48730	CSNK1D	S2427	S2421T	2421	Missense	distal	-6	no	12.268	11.051	EPSD	COSMIC	11.915	Loss
CK1_CK1_CK1-D_CSNK1D_ST	P25054	APC	P48730	CSNK1D	S2427	D2430N	2430	Missense	distal	3	no	12.268	12.709	EPSD	COSMIC	11.915	Up-regulation
CK1_CK1_CK1-D_CSNK1D_ST	P25054	APC	P48730	CSNK1D	S2427	E2428K	2428	Missense	proximal	1	no	12.268	8.886	EPSD	COSMIC	11.915	Loss
CK1_CK1_CK1-D_CSNK1D_ST	P25054	APC	P48730	CSNK1D	S2427	T2422S	2422	Missense	distal	-5	no	12.268	13.702	EPSD	COSMIC	11.915	Up-regulation
CK1_CK1_CK1-D_CSNK1D_ST	P25054	APC	P48730	CSNK1D	S2427	R2434I	2434	Missense	distal	7	no	12.268	11.969	EPSD	COSMIC	11.915	Down-regulation
CK1_CK1_CK1-D_CSNK1D_ST	P25054	APC	P48730	CSNK1D	S2464	S2466F	2466	Missense	proximal	2	no	13.202	12.528	EPSD	COSMIC	11.915	Down-regulation
CK1_CK1_CK1-D_CSNK1D_ST	P25054	APC	P48730	CSNK1D	S2464	P2467S	2467	Missense	distal	3	no	13.202	15.970	EPSD	COSMIC;GDSC;CCLE	11.915	Up-regulation
CK1_CK1_CK1-D_CSNK1D_ST	P25054	APC	P48730	CSNK1D	S2464	P2467T	2467	Missense	distal	3	no	13.202	14.435	EPSD	COSMIC	11.915	Up-regulation
CK1_CK1_CK1-D_CSNK1D_ST	P25054	APC	P48730	CSNK1D	S2464	R2470G	2470	Missense	distal	6	no	13.202	14.642	EPSD	COSMIC	11.915	Up-regulation
CK1_CK1_CK1-D_CSNK1D_ST	P25054	APC	P48730	CSNK1D	S2464	R2470T	2470	Missense	distal	6	no	13.202	13.211	EPSD	COSMIC	11.915	Up-regulation
CK1_CK1_CK1-D_CSNK1D_ST	P25054	APC	P48730	CSNK1D	S2464	E2457G	2457	Missense	distal	-7	no	13.202	12.878	EPSD	COSMIC	11.915	Down-regulation
CK1_CK1_CK1-D_CSNK1D_ST	P25054	APC	P48730	CSNK1D	S2464	E2457D	2457	Missense	distal	-7	no	13.202	12.097	EPSD	COSMIC	11.915	Down-regulation
CK1_CK1_CK1-D_CSNK1D_ST	P25054	APC	P48730	CSNK1D	S2464	E2458V	2458	Missense	distal	-6	no	13.202	12.789	EPSD	COSMIC	11.915	Down-regulation
CK1_CK1_CK1-D_CSNK1D_ST	P25054	APC	P48730	CSNK1D	S2464	R2470K	2470	Missense	distal	6	no	13.202	14.475	EPSD	COSMIC	11.915	Up-regulation
CK1_CK1_CK1-D_CSNK1D_ST	P25054	APC	P48730	CSNK1D	S2464	S2466Y	2466	Missense	proximal	2	no	13.202	11.302	EPSD	COSMIC	11.915	Loss
CK1_CK1_CK1-D_CSNK1D_ST	P25054	APC	P48730	CSNK1D	S2464	E2463D	2463	Missense	proximal	-1	no	13.202	12.687	EPSD	COSMIC	11.915	Down-regulation
CK1_CK1_CK1-D_CSNK1D_ST	P25054	APC	P48730	CSNK1D	S2557	R2560Q	2560	Missense	distal	3	no	10.511	12.305	EPSD	COSMIC	11.915	Gain
CK1_CK1_CK1-D_CSNK1D_ST	P25054	APC	P48730	CSNK1D	T2563	R2565I	2565	Missense	proximal	2	no	11.231	12.306	EPSD	COSMIC	11.915	Gain
CK1_CK1_CK1-D_CSNK1D_ST	P25054	APC	P48730	CSNK1D	T2563	S2570L	2570	Missense	distal	7	no	11.231	13.036	EPSD	COSMIC	11.915	Gain
CK1_CK1_CK1-D_CSNK1D_ST	P25054	APC	P48730	CSNK1D	S2575	I2573V	2573	Missense	proximal	-2	no	10.014	12.616	EPSD	COSMIC	11.915	Gain
CK1_CK1_CK1-D_CSNK1D_ST	P25054	APC	P48730	CSNK1D	S2578	I2573V	2573	Missense	distal	-5	no	10.030	12.092	EPSD	COSMIC	11.915	Gain
CK1_CK1_CK1-D_CSNK1D_ST	P25054	APC	P48730	CSNK1D	S2580	S2577L	2577	Missense	distal	-3	no	13.437	11.233	EPSD	COSMIC	11.915	Loss
CK1_CK1_CK1-D_CSNK1D_ST	P25054	APC	P48730	CSNK1D	S2580	S2581N	2581	Missense	proximal	1	no	13.437	14.758	EPSD	COSMIC	11.915	Up-regulation
CK1_CK1_CK1-D_CSNK1D_ST	P25054	APC	P48730	CSNK1D	S2580	I2573V	2573	Missense	distal	-7	no	13.437	12.143	EPSD	COSMIC	11.915	Down-regulation
CK1_CK1_CK1-D_CSNK1D_ST	P25054	APC	P48730	CSNK1D	S2580	E2587K	2587	Missense	distal	7	no	13.437	13.679	EPSD	COSMIC	11.915	Up-regulation
CK1_CK1_CK1-D_CSNK1D_ST	P25054	APC	P48730	CSNK1D	S2581	S2577L	2577	Missense	distal	-4	no	12.419	12.152	EPSD	COSMIC	11.915	Down-regulation
CK1_CK1_CK1-D_CSNK1D_ST	P25054	APC	P48730	CSNK1D	S2581	S2581N	2581	Missense	central	0	yes	12.419	0.000	EPSD	COSMIC	11.915	Loss
CK1_CK1_CK1-D_CSNK1D_ST	P25054	APC	P48730	CSNK1D	S2581	E2587K	2587	Missense	distal	6	no	12.419	10.621	EPSD	COSMIC	11.915	Loss
CK1_CK1_CK1-D_CSNK1D_ST	P25054	APC	P48730	CSNK1D	T2611	G2610A	2610	Missense	proximal	-1	no	11.987	12.857	EPSD	COSMIC	11.915	Up-regulation
CK1_CK1_CK1-D_CSNK1D_ST	P25054	APC	P48730	CSNK1D	T2611	A2608T	2608	Missense	distal	-3	no	11.987	12.839	EPSD	COSMIC;CCLE	11.915	Up-regulation
CK1_CK1_CK1-D_CSNK1D_ST	P25054	APC	P48730	CSNK1D	T2629	Q2628H	2628	Missense	proximal	-1	no	12.809	11.343	EPSD	COSMIC	11.915	Loss
CK1_CK1_CK1-D_CSNK1D_ST	P25054	APC	P48730	CSNK1D	T2629	G2633S	2633	Missense	distal	4	no	12.809	12.685	EPSD	COSMIC	11.915	Down-regulation
CK1_CK1_CK1-D_CSNK1D_ST	P25054	APC	P48730	CSNK1D	T2629	S2631F	2631	Missense	proximal	2	no	12.809	12.135	EPSD	COSMIC	11.915	Down-regulation
CK1_CK1_CK1-D_CSNK1D_ST	P25054	APC	P48730	CSNK1D	T2629	S2627F	2627	Missense	proximal	-2	no	12.809	11.067	EPSD	COSMIC	11.915	Loss
CK1_CK1_CK1-D_CSNK1D_ST	P25054	APC	P48730	CSNK1D	T2629	P2622S	2622	Missense	distal	-7	no	12.809	12.324	EPSD	COSMIC	11.915	Down-regulation
CK1_CK1_CK1-D_CSNK1D_ST	P25054	APC	P48730	CSNK1D	T2629	P2622L	2622	Missense	distal	-7	no	12.809	10.624	EPSD	COSMIC	11.915	Loss
CK1_CK1_CK1-D_CSNK1D_ST	P25054	APC	P48730	CSNK1D	T2629	S2625N	2625	Missense	distal	-4	no	12.809	12.560	EPSD	COSMIC	11.915	Down-regulation
CK1_CK1_CK1-D_CSNK1D_ST	P25054	APC	P48730	CSNK1D	S2631	Q2628H	2628	Missense	distal	-3	no	11.893	13.395	EPSD	COSMIC	11.915	Gain
CK1_CK1_CK1-D_CSNK1D_ST	P25054	APC	P48730	CSNK1D	T2635	Q2628H	2628	Missense	distal	-7	no	12.118	10.597	EPSD	COSMIC	11.915	Loss
CK1_CK1_CK1-D_CSNK1D_ST	P25054	APC	P48730	CSNK1D	T2635	G2637C	2637	Missense	proximal	2	no	12.118	10.913	EPSD	COSMIC	11.915	Loss
CK1_CK1_CK1-D_CSNK1D_ST	P25054	APC	P48730	CSNK1D	T2635	G2633S	2633	Missense	proximal	-2	no	12.118	11.515	EPSD	COSMIC	11.915	Loss
CK1_CK1_CK1-D_CSNK1D_ST	P25054	APC	P48730	CSNK1D	T2635	S2631F	2631	Missense	distal	-4	no	12.118	11.787	EPSD	COSMIC	11.915	Loss
CK1_CK1_CK1-D_CSNK1D_ST	P25054	APC	P48730	CSNK1D	T2635	A2638S	2638	Missense	distal	3	no	12.118	12.439	EPSD	COSMIC;GDSC;CCLE	11.915	Up-regulation
CK1_CK1_CK1-D_CSNK1D_ST	P25054	APC	P48730	CSNK1D	T2635	S2640L	2640	Missense	distal	5	no	12.118	10.859	EPSD	COSMIC	11.915	Loss
CK1_CK1_CK1-D_CSNK1D_ST	P25054	APC	P48730	CSNK1D	T2676	R2670T	2670	Missense	distal	-6	no	12.372	11.385	EPSD	COSMIC	11.915	Loss
CK1_CK1_CK1-D_CSNK1D_ST	P25054	APC	P48730	CSNK1D	T2676	V2682M	2682	Missense	distal	6	no	12.372	15.995	EPSD	COSMIC	11.915	Up-regulation
CK1_CK1_CK1-D_CSNK1D_ST	P25054	APC	P48730	CSNK1D	T2676	S2674F	2674	Missense	proximal	-2	no	12.372	10.631	EPSD	COSMIC	11.915	Loss
CK1_CK1_CK1-D_CSNK1D_ST	P25054	APC	P48730	CSNK1D	T2676	R2670I	2670	Missense	distal	-6	no	12.372	11.543	EPSD	COSMIC	11.915	Loss
CK1_CK1_CK1-D_CSNK1D_ST	P25054	APC	P48730	CSNK1D	T2679	V2682M	2682	Missense	distal	3	no	9.175	12.163	EPSD	COSMIC	11.915	Gain
CK1_CK1_CK1-D_CSNK1D_ST	P25054	APC	P48730	CSNK1D	T2782	V2781A	2781	Missense	proximal	-1	no	12.427	12.973	EPSD	COSMIC	11.915	Up-regulation
CK1_CK1_CK1-D_CSNK1D_ST	P25054	APC	P48730	CSNK1D	T2782	S2789I	2789	Missense	distal	7	no	12.427	12.655	EPSD	COSMIC	11.915	Up-regulation
CK1_CK1_CK1-D_CSNK1D_ST	P25054	APC	P48730	CSNK1D	T2782	N2787S	2787	Missense	distal	5	no	12.427	12.524	EPSD	COSMIC	11.915	Up-regulation
CK1_CK1_CK1-D_CSNK1D_ST	P25054	APC	P48730	CSNK1D	T2782	V2781M	2781	Missense	proximal	-1	no	12.427	11.311	EPSD	COSMIC	11.915	Loss
CK1_CK1_CK1-D_CSNK1D_ST	P25054	APC	P48730	CSNK1D	S2797	D2796N	2796	Missense	proximal	-1	no	12.827	12.824	EPSD	COSMIC	11.915	Down-regulation
CK1_CK1_CK1-D_CSNK1D_ST	P25054	APC	P48730	CSNK1D	S2797	P2790L	2790	Missense	distal	-7	no	12.827	10.642	EPSD	COSMIC	11.915	Loss
CK1_CK1_CK1-D_CSNK1D_ST	P25054	APC	P48730	CSNK1D	S2797	S2803P	2803	Missense	distal	6	no	12.827	10.535	EPSD	COSMIC	11.915	Loss
CK1_CK1_CK1-D_CSNK1D_ST	P25054	APC	P48730	CSNK1D	S2797	S2793G	2793	Missense	distal	-4	no	12.827	12.535	EPSD	COSMIC	11.915	Down-regulation
CK1_CK1_CK1-D_CSNK1D_ST	P25054	APC	P48730	CSNK1D	S2797	T2798A	2798	Missense	proximal	1	no	12.827	11.246	EPSD	COSMIC	11.915	Loss
CK1_CK1_CK1-D_CSNK1D_ST	P25054	APC	P48730	CSNK1D	S2797	K2792R	2792	Missense	distal	-5	no	12.827	13.263	EPSD	COSMIC	11.915	Up-regulation
CK1_CK1_CK1-D_CSNK1D_ST	P25054	APC	P48730	CSNK1D	S2797	D2796G	2796	Missense	proximal	-1	no	12.827	12.429	EPSD	COSMIC;GDSC;CCLE	11.915	Down-regulation
CK1_CK1_CK1-D_CSNK1D_ST	P25054	APC	P48730	CSNK1D	S2797	R2791S	2791	Missense	distal	-6	no	12.827	13.056	EPSD	COSMIC	11.915	Up-regulation
CK1_CK1_CK1-D_CSNK1D_ST	P25054	APC	P48730	CSNK1D	S2826	T2820I	2820	Missense	distal	-6	no	12.151	12.309	EPSD	COSMIC	11.915	Up-regulation
CK1_CK1_CK1-D_CSNK1D_ST	P25054	APC	P48730	CSNK1D	S2826	S2825F	2825	Missense	proximal	-1	no	12.151	12.664	EPSD	COSMIC	11.915	Up-regulation
CK1_CK1_CK1-D_CSNK1D_ST	P25054	APC	P48730	CSNK1D	S2826	D2821G	2821	Missense	distal	-5	no	12.151	12.357	EPSD	COSMIC	11.915	Up-regulation
CK1_CK1_CK1-D_CSNK1D_ST	P25054	APC	P48730	CSNK1D	S2826	S2822N	2822	Missense	distal	-4	no	12.151	11.902	EPSD	COSMIC	11.915	Loss
CK1_CK1_CK1-D_CSNK1D_ST	P25054	APC	P48730	CSNK1D	S2826	R2833C	2833	Missense	distal	7	no	12.151	10.237	EPSD	COSMIC	11.915	Loss
CK1_CK1_CK1-D_CSNK1D_ST	P25054	APC	P48730	CSNK1D	S2826	R2833H	2833	Missense	distal	7	no	12.151	15.105	EPSD	COSMIC	11.915	Up-regulation
CK1_CK1_CK1-D_CSNK1D_ST	P25054	APC	P48730	CSNK1D	S2826	G2827E	2827	Missense	proximal	1	no	12.151	11.537	EPSD	COSMIC	11.915	Loss
CK1_CK1_CK1-D_CSNK1D_ST	P25054	APC	P48730	CSNK1D	S2826	E2824Q	2824	Missense	proximal	-2	no	12.151	11.837	EPSD	COSMIC	11.915	Loss
CK1_CK1_CK1-D_CSNK1D_ST	P04637	TP53	P48730	CSNK1D	S6	E11Q	11	Missense	distal	5	no	15.860	15.397	EPSD	COSMIC;GDSC;CCLE	11.915	Down-regulation
CK1_CK1_CK1-D_CSNK1D_ST	P04637	TP53	P48730	CSNK1D	S6	P13S	13	Missense	distal	7	no	15.860	14.999	EPSD	COSMIC	11.915	Down-regulation
CK1_CK1_CK1-D_CSNK1D_ST	P04637	TP53	P48730	CSNK1D	S6	V10I	10	Missense	distal	4	no	15.860	14.709	EPSD	COSMIC	11.915	Down-regulation
CK1_CK1_CK1-D_CSNK1D_ST	P04637	TP53	P48730	CSNK1D	S6	P8L	8	Missense	proximal	2	no	15.860	14.955	EPSD	COSMIC	11.915	Down-regulation
CK1_CK1_CK1-D_CSNK1D_ST	P04637	TP53	P48730	CSNK1D	S6	P8S	8	Missense	proximal	2	no	15.860	16.474	EPSD	COSMIC	11.915	Up-regulation
CK1_CK1_CK1-D_CSNK1D_ST	P04637	TP53	P48730	CSNK1D	S6	P13L	13	Missense	distal	7	no	15.860	16.805	EPSD	COSMIC	11.915	Up-regulation
CK1_CK1_CK1-D_CSNK1D_ST	P04637	TP53	P48730	CSNK1D	S6	Q5H	5	Missense	proximal	-1	no	15.860	14.394	EPSD	COSMIC	11.915	Down-regulation
CK1_CK1_CK1-D_CSNK1D_ST	P04637	TP53	P48730	CSNK1D	S6	V10G	10	Missense	distal	4	no	15.860	14.902	EPSD	COSMIC	11.915	Down-regulation
CK1_CK1_CK1-D_CSNK1D_ST	P04637	TP53	P48730	CSNK1D	S6	E3G	3	Missense	distal	-3	no	15.860	15.759	EPSD	COSMIC	11.915	Down-regulation
CK1_CK1_CK1-D_CSNK1D_ST	P04637	TP53	P48730	CSNK1D	S6	D7H	7	Missense	proximal	1	no	15.860	16.691	EPSD	COSMIC	11.915	Up-regulation
CK1_CK1_CK1-D_CSNK1D_ST	P04637	TP53	P48730	CSNK1D	S6	S9G	9	Missense	distal	3	no	15.860	14.938	EPSD	COSMIC	11.915	Down-regulation
CK1_CK1_CK1-D_CSNK1D_ST	P04637	TP53	P48730	CSNK1D	S6	D7Y	7	Missense	proximal	1	no	15.860	13.340	EPSD	COSMIC	11.915	Down-regulation
CK1_CK1_CK1-D_CSNK1D_ST	P04637	TP53	P48730	CSNK1D	S9	E11Q	11	Missense	proximal	2	no	18.861	18.220	PhosphoSitePlus;EPSD	COSMIC;GDSC;CCLE	11.915	Down-regulation
CK1_CK1_CK1-D_CSNK1D_ST	P04637	TP53	P48730	CSNK1D	S9	Q16L	16	Missense	distal	7	no	18.861	18.870	PhosphoSitePlus;EPSD	COSMIC;GDSC;CCLE	11.915	Up-regulation
CK1_CK1_CK1-D_CSNK1D_ST	P04637	TP53	P48730	CSNK1D	S9	P13S	13	Missense	distal	4	no	18.861	18.556	PhosphoSitePlus;EPSD	COSMIC	11.915	Down-regulation
CK1_CK1_CK1-D_CSNK1D_ST	P04637	TP53	P48730	CSNK1D	S9	V10I	10	Missense	proximal	1	no	18.861	16.162	PhosphoSitePlus;EPSD	COSMIC	11.915	Down-regulation
CK1_CK1_CK1-D_CSNK1D_ST	P04637	TP53	P48730	CSNK1D	S9	P8L	8	Missense	proximal	-1	no	18.861	19.155	PhosphoSitePlus;EPSD	COSMIC	11.915	Up-regulation
CK1_CK1_CK1-D_CSNK1D_ST	P04637	TP53	P48730	CSNK1D	S9	P8S	8	Missense	proximal	-1	no	18.861	19.040	PhosphoSitePlus;EPSD	COSMIC	11.915	Up-regulation
CK1_CK1_CK1-D_CSNK1D_ST	P04637	TP53	P48730	CSNK1D	S9	P13L	13	Missense	distal	4	no	18.861	18.920	PhosphoSitePlus;EPSD	COSMIC	11.915	Up-regulation
CK1_CK1_CK1-D_CSNK1D_ST	P04637	TP53	P48730	CSNK1D	S9	Q5H	5	Missense	distal	-4	no	18.861	18.586	PhosphoSitePlus;EPSD	COSMIC	11.915	Down-regulation
CK1_CK1_CK1-D_CSNK1D_ST	P04637	TP53	P48730	CSNK1D	S9	V10G	10	Missense	proximal	1	no	18.861	18.756	PhosphoSitePlus;EPSD	COSMIC	11.915	Down-regulation
CK1_CK1_CK1-D_CSNK1D_ST	P04637	TP53	P48730	CSNK1D	S9	E3G	3	Missense	distal	-6	no	18.861	17.954	PhosphoSitePlus;EPSD	COSMIC	11.915	Down-regulation
CK1_CK1_CK1-D_CSNK1D_ST	P04637	TP53	P48730	CSNK1D	S9	D7H	7	Missense	proximal	-2	no	18.861	19.583	PhosphoSitePlus;EPSD	COSMIC	11.915	Up-regulation
CK1_CK1_CK1-D_CSNK1D_ST	P04637	TP53	P48730	CSNK1D	S9	S9G	9	Missense	central	0	yes	18.861	0.000	PhosphoSitePlus;EPSD	COSMIC	11.915	Loss
CK1_CK1_CK1-D_CSNK1D_ST	P04637	TP53	P48730	CSNK1D	S9	S15I	15	Missense	distal	6	no	18.861	16.146	PhosphoSitePlus;EPSD	COSMIC	11.915	Down-regulation
CK1_CK1_CK1-D_CSNK1D_ST	P04637	TP53	P48730	CSNK1D	S9	D7Y	7	Missense	proximal	-2	no	18.861	14.428	PhosphoSitePlus;EPSD	COSMIC	11.915	Down-regulation
CK1_CK1_CK1-D_CSNK1D_ST	P04637	TP53	P48730	CSNK1D	S15	E11Q	11	Missense	distal	-4	no	13.127	13.026	EPSD	COSMIC;GDSC;CCLE	11.915	Down-regulation
CK1_CK1_CK1-D_CSNK1D_ST	P04637	TP53	P48730	CSNK1D	S15	S20L	20	Missense	distal	5	no	13.127	11.868	EPSD	COSMIC	11.915	Loss
CK1_CK1_CK1-D_CSNK1D_ST	P04637	TP53	P48730	CSNK1D	S15	Q16L	16	Missense	proximal	1	no	13.127	13.537	EPSD	COSMIC;GDSC;CCLE	11.915	Up-regulation
CK1_CK1_CK1-D_CSNK1D_ST	P04637	TP53	P48730	CSNK1D	S15	P13S	13	Missense	proximal	-2	no	13.127	14.016	EPSD	COSMIC	11.915	Up-regulation
CK1_CK1_CK1-D_CSNK1D_ST	P04637	TP53	P48730	CSNK1D	S15	E17K	17	Missense	proximal	2	no	13.127	12.365	EPSD	COSMIC	11.915	Down-regulation
CK1_CK1_CK1-D_CSNK1D_ST	P04637	TP53	P48730	CSNK1D	S15	V10I	10	Missense	distal	-5	no	13.127	11.064	EPSD	COSMIC	11.915	Loss
CK1_CK1_CK1-D_CSNK1D_ST	P04637	TP53	P48730	CSNK1D	S15	P8L	8	Missense	distal	-7	no	13.127	10.942	EPSD	COSMIC	11.915	Loss
CK1_CK1_CK1-D_CSNK1D_ST	P04637	TP53	P48730	CSNK1D	S15	P8S	8	Missense	distal	-7	no	13.127	12.642	EPSD	COSMIC	11.915	Down-regulation
CK1_CK1_CK1-D_CSNK1D_ST	P04637	TP53	P48730	CSNK1D	S15	P13L	13	Missense	proximal	-2	no	13.127	10.395	EPSD	COSMIC	11.915	Loss
CK1_CK1_CK1-D_CSNK1D_ST	P04637	TP53	P48730	CSNK1D	S15	V10G	10	Missense	distal	-5	no	13.127	12.422	EPSD	COSMIC	11.915	Down-regulation
CK1_CK1_CK1-D_CSNK1D_ST	P04637	TP53	P48730	CSNK1D	S15	T18A	18	Missense	distal	3	no	13.127	14.341	EPSD	COSMIC	11.915	Up-regulation
CK1_CK1_CK1-D_CSNK1D_ST	P04637	TP53	P48730	CSNK1D	S15	F19S	19	Missense	distal	4	no	13.127	12.704	EPSD	COSMIC	11.915	Down-regulation
CK1_CK1_CK1-D_CSNK1D_ST	P04637	TP53	P48730	CSNK1D	S15	E17V	17	Missense	proximal	2	no	13.127	12.183	EPSD	COSMIC	11.915	Down-regulation
CK1_CK1_CK1-D_CSNK1D_ST	P04637	TP53	P48730	CSNK1D	S15	S9G	9	Missense	distal	-6	no	13.127	12.479	EPSD	COSMIC	11.915	Down-regulation
CK1_CK1_CK1-D_CSNK1D_ST	P04637	TP53	P48730	CSNK1D	S15	T18I	18	Missense	distal	3	no	13.127	11.706	EPSD	COSMIC	11.915	Loss
CK1_CK1_CK1-D_CSNK1D_ST	P04637	TP53	P48730	CSNK1D	S15	T18K	18	Missense	distal	3	no	13.127	13.295	EPSD	COSMIC	11.915	Up-regulation
CK1_CK1_CK1-D_CSNK1D_ST	P04637	TP53	P48730	CSNK1D	S15	T18R	18	Missense	distal	3	no	13.127	11.420	EPSD	COSMIC	11.915	Loss
CK1_CK1_CK1-D_CSNK1D_ST	P04637	TP53	P48730	CSNK1D	S15	S15I	15	Missense	central	0	yes	13.127	0.000	EPSD	COSMIC	11.915	Loss
CK1_CK1_CK1-D_CSNK1D_ST	P04637	TP53	P48730	CSNK1D	S20	S20L	20	Missense	central	0	yes	12.521	0.000	EPSD;PhosphoSitePlus	COSMIC	11.915	Loss
CK1_CK1_CK1-D_CSNK1D_ST	P04637	TP53	P48730	CSNK1D	S20	Q16L	16	Missense	distal	-4	no	12.521	12.457	EPSD;PhosphoSitePlus	COSMIC;GDSC;CCLE	11.915	Down-regulation
CK1_CK1_CK1-D_CSNK1D_ST	P04637	TP53	P48730	CSNK1D	S20	P13S	13	Missense	distal	-7	no	12.521	12.036	EPSD;PhosphoSitePlus	COSMIC	11.915	Down-regulation
CK1_CK1_CK1-D_CSNK1D_ST	P04637	TP53	P48730	CSNK1D	S20	E17K	17	Missense	distal	-3	no	12.521	9.874	EPSD;PhosphoSitePlus	COSMIC	11.915	Loss
CK1_CK1_CK1-D_CSNK1D_ST	P04637	TP53	P48730	CSNK1D	S20	P13L	13	Missense	distal	-7	no	12.521	10.336	EPSD;PhosphoSitePlus	COSMIC	11.915	Loss
CK1_CK1_CK1-D_CSNK1D_ST	P04637	TP53	P48730	CSNK1D	S20	L26P	26	Missense	distal	6	no	12.521	11.914	EPSD;PhosphoSitePlus	COSMIC	11.915	Loss
CK1_CK1_CK1-D_CSNK1D_ST	P04637	TP53	P48730	CSNK1D	S20	T18A	18	Missense	proximal	-2	no	12.521	12.179	EPSD;PhosphoSitePlus	COSMIC	11.915	Down-regulation
CK1_CK1_CK1-D_CSNK1D_ST	P04637	TP53	P48730	CSNK1D	S20	F19S	19	Missense	proximal	-1	no	12.521	12.008	EPSD;PhosphoSitePlus	COSMIC	11.915	Down-regulation
CK1_CK1_CK1-D_CSNK1D_ST	P04637	TP53	P48730	CSNK1D	S20	E17V	17	Missense	distal	-3	no	12.521	9.827	EPSD;PhosphoSitePlus	COSMIC	11.915	Loss
CK1_CK1_CK1-D_CSNK1D_ST	P04637	TP53	P48730	CSNK1D	S20	P27T	27	Missense	distal	7	no	12.521	13.915	EPSD;PhosphoSitePlus	COSMIC	11.915	Up-regulation
CK1_CK1_CK1-D_CSNK1D_ST	P04637	TP53	P48730	CSNK1D	S20	T18I	18	Missense	proximal	-2	no	12.521	6.876	EPSD;PhosphoSitePlus	COSMIC	11.915	Loss
CK1_CK1_CK1-D_CSNK1D_ST	P04637	TP53	P48730	CSNK1D	S20	T18K	18	Missense	proximal	-2	no	12.521	10.719	EPSD;PhosphoSitePlus	COSMIC	11.915	Loss
CK1_CK1_CK1-D_CSNK1D_ST	P04637	TP53	P48730	CSNK1D	S20	T18R	18	Missense	proximal	-2	no	12.521	10.198	EPSD;PhosphoSitePlus	COSMIC	11.915	Loss
CK1_CK1_CK1-D_CSNK1D_ST	P04637	TP53	P48730	CSNK1D	S20	S15I	15	Missense	distal	-5	no	12.521	11.378	EPSD;PhosphoSitePlus	COSMIC	11.915	Loss
CK1_CK1_CK1-D_CSNK1D_ST	P04637	TP53	P48730	CSNK1D	S37	L35R	35	Missense	proximal	-2	no	9.023	11.928	EPSD	COSMIC	11.915	Gain
CK1_CK1_CK1-D_CSNK1D_ST	P04637	TP53	P48730	CSNK1D	S37	L35H	35	Missense	proximal	-2	no	9.023	14.076	EPSD	COSMIC	11.915	Gain
CK1_CK1_CK1-D_CSNK1D_ST	P04637	TP53	P48730	CSNK1D	S46	M44T	44	Missense	proximal	-2	no	10.073	13.319	EPSD	COSMIC	11.915	Gain
CK1_CK1_CK1-D_CSNK1D_ST	P04637	TP53	P48730	CSNK1D	S127	C124W	124	Missense	distal	-3	no	12.589	11.416	EPSD	COSMIC	11.915	Loss
CK1_CK1_CK1-D_CSNK1D_ST	P04637	TP53	P48730	CSNK1D	S127	C124F	124	Missense	distal	-3	no	12.589	12.327	EPSD	COSMIC	11.915	Down-regulation
CK1_CK1_CK1-D_CSNK1D_ST	P04637	TP53	P48730	CSNK1D	S127	C124S	124	Missense	distal	-3	no	12.589	14.413	EPSD	COSMIC	11.915	Up-regulation
CK1_CK1_CK1-D_CSNK1D_ST	P04637	TP53	P48730	CSNK1D	S127	S127A	127	Missense	central	0	yes	12.589	0.000	EPSD	COSMIC	11.915	Loss
CK1_CK1_CK1-D_CSNK1D_ST	P04637	TP53	P48730	CSNK1D	S127	S127L	127	Missense	central	0	yes	12.589	0.000	EPSD	COSMIC	11.915	Loss
CK1_CK1_CK1-D_CSNK1D_ST	P04637	TP53	P48730	CSNK1D	S127	C124T	124	Missense	distal	-3	no	12.589	12.731	EPSD	COSMIC	11.915	Up-regulation
CK1_CK1_CK1-D_CSNK1D_ST	P04637	TP53	P48730	CSNK1D	S127	S127I	127	Missense	central	0	yes	12.589	0.000	EPSD	COSMIC	11.915	Loss
CK1_CK1_CK1-D_CSNK1D_ST	P04637	TP53	P48730	CSNK1D	S127	S127G	127	Missense	central	0	yes	12.589	0.000	EPSD	COSMIC	11.915	Loss
CK1_CK1_CK1-D_CSNK1D_ST	P04637	TP53	P48730	CSNK1D	S127	N131H	131	Missense	distal	4	no	12.589	13.658	EPSD	COSMIC	11.915	Up-regulation
CK1_CK1_CK1-D_CSNK1D_ST	P04637	TP53	P48730	CSNK1D	S127	N131D	131	Missense	distal	4	no	12.589	13.290	EPSD	COSMIC	11.915	Up-regulation
CK1_CK1_CK1-D_CSNK1D_ST	P04637	TP53	P48730	CSNK1D	S127	T125I	125	Missense	proximal	-2	no	12.589	6.944	EPSD	COSMIC	11.915	Loss
CK1_CK1_CK1-D_CSNK1D_ST	P04637	TP53	P48730	CSNK1D	S127	F134I	134	Missense	distal	7	no	12.589	10.803	EPSD	COSMIC	11.915	Loss
CK1_CK1_CK1-D_CSNK1D_ST	P04637	TP53	P48730	CSNK1D	S127	K120T	120	Missense	distal	-7	no	12.589	12.298	EPSD	COSMIC	11.915	Down-regulation
CK1_CK1_CK1-D_CSNK1D_ST	P04637	TP53	P48730	CSNK1D	S127	F134S	134	Missense	distal	7	no	12.589	10.575	EPSD	COSMIC	11.915	Loss
CK1_CK1_CK1-D_CSNK1D_ST	P04637	TP53	P48730	CSNK1D	S127	T125K	125	Missense	proximal	-2	no	12.589	10.787	EPSD	COSMIC	11.915	Loss
CK1_CK1_CK1-D_CSNK1D_ST	P04637	TP53	P48730	CSNK1D	S127	M133I	133	Missense	distal	6	no	12.589	8.988	EPSD	COSMIC	11.915	Loss
CK1_CK1_CK1-D_CSNK1D_ST	P04637	TP53	P48730	CSNK1D	S127	N131K	131	Missense	distal	4	no	12.589	13.135	EPSD	COSMIC;CCLE	11.915	Up-regulation
CK1_CK1_CK1-D_CSNK1D_ST	P04637	TP53	P48730	CSNK1D	S127	P128S	128	Missense	proximal	1	no	12.589	10.270	EPSD	COSMIC	11.915	Loss
CK1_CK1_CK1-D_CSNK1D_ST	P04637	TP53	P48730	CSNK1D	S127	M133L	133	Missense	distal	6	no	12.589	10.018	EPSD	COSMIC	11.915	Loss
CK1_CK1_CK1-D_CSNK1D_ST	P04637	TP53	P48730	CSNK1D	S127	A129T	129	Missense	proximal	2	no	12.589	11.083	EPSD	COSMIC	11.915	Loss
CK1_CK1_CK1-D_CSNK1D_ST	P04637	TP53	P48730	CSNK1D	S127	T123I	123	Missense	distal	-4	no	12.589	12.965	EPSD	COSMIC	11.915	Up-regulation
CK1_CK1_CK1-D_CSNK1D_ST	P04637	TP53	P48730	CSNK1D	S127	A129G	129	Missense	proximal	2	no	12.589	12.224	EPSD	COSMIC	11.915	Down-regulation
CK1_CK1_CK1-D_CSNK1D_ST	P04637	TP53	P48730	CSNK1D	S127	K132W	132	Missense	distal	5	no	12.589	11.526	EPSD	COSMIC	11.915	Loss
CK1_CK1_CK1-D_CSNK1D_ST	P04637	TP53	P48730	CSNK1D	S127	A129V	129	Missense	proximal	2	no	12.589	11.429	EPSD	COSMIC	11.915	Loss
CK1_CK1_CK1-D_CSNK1D_ST	P04637	TP53	P48730	CSNK1D	S127	P128A	128	Missense	proximal	1	no	12.589	9.833	EPSD	COSMIC	11.915	Loss
CK1_CK1_CK1-D_CSNK1D_ST	P04637	TP53	P48730	CSNK1D	S127	L130I	130	Missense	distal	3	no	12.589	11.420	EPSD	COSMIC	11.915	Loss
CK1_CK1_CK1-D_CSNK1D_ST	P04637	TP53	P48730	CSNK1D	S127	S121F	121	Missense	distal	-6	no	12.589	11.860	EPSD	COSMIC	11.915	Loss
CK1_CK1_CK1-D_CSNK1D_ST	P04637	TP53	P48730	CSNK1D	S127	A129D	129	Missense	proximal	2	no	12.589	12.227	EPSD	COSMIC	11.915	Down-regulation
CK1_CK1_CK1-D_CSNK1D_ST	P04637	TP53	P48730	CSNK1D	S127	K120Q	120	Missense	distal	-7	no	12.589	13.064	EPSD	COSMIC	11.915	Up-regulation
CK1_CK1_CK1-D_CSNK1D_ST	P04637	TP53	P48730	CSNK1D	S127	T125S	125	Missense	proximal	-2	no	12.589	10.981	EPSD	COSMIC	11.915	Loss
CK1_CK1_CK1-D_CSNK1D_ST	P04637	TP53	P48730	CSNK1D	S127	P128L	128	Missense	proximal	1	no	12.589	12.540	EPSD	COSMIC	11.915	Down-regulation
CK1_CK1_CK1-D_CSNK1D_ST	P04637	TP53	P48730	CSNK1D	S127	V122L	122	Missense	distal	-5	no	12.589	10.029	EPSD	COSMIC	11.915	Loss
CK1_CK1_CK1-D_CSNK1D_ST	P04637	TP53	P48730	CSNK1D	S127	C124L	124	Missense	distal	-3	no	12.589	12.209	EPSD	COSMIC	11.915	Down-regulation
CK1_CK1_CK1-D_CSNK1D_ST	P04637	TP53	P48730	CSNK1D	S127	N131T	131	Missense	distal	4	no	12.589	13.172	EPSD	COSMIC	11.915	Up-regulation
CK1_CK1_CK1-D_CSNK1D_ST	P04637	TP53	P48730	CSNK1D	S127	M133V	133	Missense	distal	6	no	12.589	8.965	EPSD	COSMIC	11.915	Loss
CK1_CK1_CK1-D_CSNK1D_ST	P04637	TP53	P48730	CSNK1D	S362	P359S	359	Missense	distal	-3	no	8.183	12.183	EPSD	COSMIC	11.915	Gain
CK1_CK1_CK1-D_CSNK1D_ST	P04637	TP53	P48730	CSNK1D	S367	A364D	364	Missense	distal	-3	no	9.315	12.083	EPSD	COSMIC	11.915	Gain
CK1_CK1_CK1-D_CSNK1D_ST	P49810	PSEN2	P48730	CSNK1D	S9	E10K	10	Missense	proximal	1	no	13.968	10.587	EPSD	COSMIC	11.915	Loss
CK1_CK1_CK1-D_CSNK1D_ST	P49810	PSEN2	P48730	CSNK1D	S9	S9N	9	Missense	central	0	yes	13.968	0.000	EPSD	COSMIC;GDSC;CCLE	11.915	Loss
CK1_CK1_CK1-D_CSNK1D_ST	P49810	PSEN2	P48730	CSNK1D	T18	M21L	21	Missense	distal	3	no	13.520	12.243	EPSD	COSMIC	11.915	Down-regulation
CK1_CK1_CK1-D_CSNK1D_ST	P49810	PSEN2	P48730	CSNK1D	S19	M21L	21	Missense	proximal	2	no	14.760	13.995	EPSD	COSMIC	11.915	Down-regulation
CK1_CK1_CK1-D_CSNK1D_ST	P49810	PSEN2	P48730	CSNK1D	T27	M21L	21	Missense	distal	-6	no	15.278	15.664	EPSD	COSMIC	11.915	Up-regulation
CK1_CK1_CK1-D_CSNK1D_ST	P49810	PSEN2	P48730	CSNK1D	T27	P28S	28	Missense	proximal	1	no	15.278	12.959	EPSD	COSMIC	11.915	Down-regulation
CK1_CK1_CK1-D_CSNK1D_ST	P49810	PSEN2	P48730	CSNK1D	T27	G34D	34	Missense	distal	7	no	15.278	15.481	EPSD	COSMIC;GDSC;CCLE	11.915	Up-regulation
CK1_CK1_CK1-D_CSNK1D_ST	P49810	PSEN2	P48730	CSNK1D	S327	E325G	325	Missense	proximal	-2	no	18.777	18.298	EPSD;PhosphoSitePlus	COSMIC	11.915	Down-regulation
CK1_CK1_CK1-D_CSNK1D_ST	P49810	PSEN2	P48730	CSNK1D	S327	E322A	322	Missense	distal	-5	no	18.777	18.174	EPSD;PhosphoSitePlus	COSMIC	11.915	Down-regulation
CK1_CK1_CK1-D_CSNK1D_ST	P49810	PSEN2	P48730	CSNK1D	S327	D320N	320	Missense	distal	-7	no	18.777	19.641	EPSD;PhosphoSitePlus	COSMIC	11.915	Up-regulation
CK1_CK1_CK1-D_CSNK1D_ST	P49810	PSEN2	P48730	CSNK1D	S327	E324G	324	Missense	distal	-3	no	18.777	18.676	EPSD;PhosphoSitePlus	COSMIC	11.915	Down-regulation
CK1_CK1_CK1-D_CSNK1D_ST	P49810	PSEN2	P48730	CSNK1D	S330	P337H	337	Missense	distal	7	no	13.880	16.499	PhosphoSitePlus;EPSD	COSMIC	11.915	Up-regulation
CK1_CK1_CK1-D_CSNK1D_ST	P49810	PSEN2	P48730	CSNK1D	S330	E325G	325	Missense	distal	-5	no	13.880	13.066	PhosphoSitePlus;EPSD	COSMIC	11.915	Down-regulation
CK1_CK1_CK1-D_CSNK1D_ST	P49810	PSEN2	P48730	CSNK1D	S330	S335L	335	Missense	distal	5	no	13.880	12.622	PhosphoSitePlus;EPSD	COSMIC	11.915	Down-regulation
CK1_CK1_CK1-D_CSNK1D_ST	P49810	PSEN2	P48730	CSNK1D	S330	E324G	324	Missense	distal	-6	no	13.880	12.974	PhosphoSitePlus;EPSD	COSMIC	11.915	Down-regulation
CK1_CK1_CK1-D_CSNK1D_ST	P35222	CTNNB1	P48730	CSNK1D	T3	A5V	5	Missense	proximal	2	no	15.968	14.809	EPSD	COSMIC	11.915	Down-regulation
CK1_CK1_CK1-D_CSNK1D_ST	P35222	CTNNB1	P48730	CSNK1D	T3	Q4H	4	Missense	proximal	1	no	15.968	17.567	EPSD	COSMIC	11.915	Up-regulation
CK1_CK1_CK1-D_CSNK1D_ST	P35222	CTNNB1	P48730	CSNK1D	T3	M8I	8	Missense	distal	5	no	15.968	15.461	EPSD	COSMIC	11.915	Down-regulation
CK1_CK1_CK1-D_CSNK1D_ST	P35222	CTNNB1	P48730	CSNK1D	T3	T3I	3	Missense	central	0	yes	15.968	0.000	EPSD	COSMIC	11.915	Loss
CK1_CK1_CK1-D_CSNK1D_ST	P35222	CTNNB1	P48730	CSNK1D	T3	E9K	9	Missense	distal	6	no	15.968	14.170	EPSD	COSMIC	11.915	Down-regulation
CK1_CK1_CK1-D_CSNK1D_ST	P35222	CTNNB1	P48730	CSNK1D	T3	D6G	6	Missense	distal	3	no	15.968	15.846	EPSD	COSMIC;GDSC;CCLE	11.915	Down-regulation
CK1_CK1_CK1-D_CSNK1D_ST	P35222	CTNNB1	P48730	CSNK1D	S23	Q28E	28	Missense	distal	5	no	12.113	12.576	EPSD	COSMIC	11.915	Up-regulation
CK1_CK1_CK1-D_CSNK1D_ST	P35222	CTNNB1	P48730	CSNK1D	S23	A21V	21	Missense	proximal	-2	no	12.113	9.413	EPSD	COSMIC	11.915	Loss
CK1_CK1_CK1-D_CSNK1D_ST	P35222	CTNNB1	P48730	CSNK1D	S23	A21T	21	Missense	proximal	-2	no	12.113	12.454	EPSD	COSMIC	11.915	Up-regulation
CK1_CK1_CK1-D_CSNK1D_ST	P35222	CTNNB1	P48730	CSNK1D	S23	V22I	22	Missense	proximal	-1	no	12.113	12.928	EPSD	COSMIC	11.915	Up-regulation
CK1_CK1_CK1-D_CSNK1D_ST	P35222	CTNNB1	P48730	CSNK1D	S23	S29P	29	Missense	distal	6	no	12.113	9.821	EPSD	COSMIC	11.915	Loss
CK1_CK1_CK1-D_CSNK1D_ST	P35222	CTNNB1	P48730	CSNK1D	S23	A20V	20	Missense	distal	-3	no	12.113	11.306	EPSD	COSMIC	11.915	Loss
CK1_CK1_CK1-D_CSNK1D_ST	P35222	CTNNB1	P48730	CSNK1D	S23	P16T	16	Missense	distal	-7	no	12.113	10.383	EPSD	COSMIC	11.915	Loss
CK1_CK1_CK1-D_CSNK1D_ST	P35222	CTNNB1	P48730	CSNK1D	S23	D17H	17	Missense	distal	-6	no	12.113	10.970	EPSD	COSMIC	11.915	Loss
CK1_CK1_CK1-D_CSNK1D_ST	P35222	CTNNB1	P48730	CSNK1D	S23	Q27H	27	Missense	distal	4	no	12.113	12.591	EPSD	COSMIC	11.915	Up-regulation
CK1_CK1_CK1-D_CSNK1D_ST	P35222	CTNNB1	P48730	CSNK1D	S23	S23N	23	Missense	central	0	yes	12.113	0.000	EPSD	COSMIC	11.915	Loss
CK1_CK1_CK1-D_CSNK1D_ST	P35222	CTNNB1	P48730	CSNK1D	S23	S29F	29	Missense	distal	6	no	12.113	11.565	EPSD	COSMIC	11.915	Loss
CK1_CK1_CK1-D_CSNK1D_ST	P35222	CTNNB1	P48730	CSNK1D	S23	Y30C	30	Missense	distal	7	no	12.113	9.866	EPSD	COSMIC	11.915	Loss
CK1_CK1_CK1-D_CSNK1D_ST	P35222	CTNNB1	P48730	CSNK1D	S23	S29Y	29	Missense	distal	6	no	12.113	9.276	EPSD	COSMIC	11.915	Loss
CK1_CK1_CK1-D_CSNK1D_ST	P35222	CTNNB1	P48730	CSNK1D	S23	S23R	23	Missense	central	0	yes	12.113	0.000	EPSD	COSMIC	11.915	Loss
CK1_CK1_CK1-D_CSNK1D_ST	P35222	CTNNB1	P48730	CSNK1D	S23	H24Y	24	Missense	proximal	1	no	12.113	8.762	EPSD	COSMIC	11.915	Loss
CK1_CK1_CK1-D_CSNK1D_ST	P35222	CTNNB1	P48730	CSNK1D	S23	W25R	25	Missense	proximal	2	no	12.113	15.741	EPSD	COSMIC	11.915	Up-regulation
CK1_CK1_CK1-D_CSNK1D_ST	P35222	CTNNB1	P48730	CSNK1D	S23	V22A	22	Missense	proximal	-1	no	12.113	12.659	EPSD	COSMIC	11.915	Up-regulation
CK1_CK1_CK1-D_CSNK1D_ST	P35222	CTNNB1	P48730	CSNK1D	S23	W25L	25	Missense	proximal	2	no	12.113	14.456	EPSD	COSMIC	11.915	Up-regulation
CK1_CK1_CK1-D_CSNK1D_ST	P35222	CTNNB1	P48730	CSNK1D	S23	H24Q	24	Missense	proximal	1	no	12.113	10.514	EPSD	COSMIC	11.915	Loss
CK1_CK1_CK1-D_CSNK1D_ST	P35222	CTNNB1	P48730	CSNK1D	S23	S23G	23	Missense	central	0	yes	12.113	0.000	EPSD	COSMIC	11.915	Loss
CK1_CK1_CK1-D_CSNK1D_ST	P35222	CTNNB1	P48730	CSNK1D	S23	V22G	22	Missense	proximal	-1	no	12.113	11.788	EPSD	COSMIC	11.915	Loss
CK1_CK1_CK1-D_CSNK1D_ST	P35222	CTNNB1	P48730	CSNK1D	S23	S29A	29	Missense	distal	6	no	12.113	10.472	EPSD	COSMIC	11.915	Loss
CK1_CK1_CK1-D_CSNK1D_ST	P35222	CTNNB1	P48730	CSNK1D	S23	D17Y	17	Missense	distal	-6	no	12.113	10.522	EPSD	COSMIC	11.915	Loss
CK1_CK1_CK1-D_CSNK1D_ST	P35222	CTNNB1	P48730	CSNK1D	S23	A21D	21	Missense	proximal	-2	no	12.113	11.557	EPSD	COSMIC	11.915	Loss
CK1_CK1_CK1-D_CSNK1D_ST	P35222	CTNNB1	P48730	CSNK1D	S23	P16L	16	Missense	distal	-7	no	12.113	9.928	EPSD	COSMIC	11.915	Loss
CK1_CK1_CK1-D_CSNK1D_ST	P35222	CTNNB1	P48730	CSNK1D	S23	Y30S	30	Missense	distal	7	no	12.113	11.254	EPSD	COSMIC	11.915	Loss
CK1_CK1_CK1-D_CSNK1D_ST	P35222	CTNNB1	P48730	CSNK1D	S23	H24R	24	Missense	proximal	1	no	12.113	9.993	EPSD	COSMIC	11.915	Loss
CK1_CK1_CK1-D_CSNK1D_ST	P35222	CTNNB1	P48730	CSNK1D	S23	Q26R	26	Missense	distal	3	no	12.113	10.319	EPSD	COSMIC;GDSC;CCLE	11.915	Loss
CK1_CK1_CK1-D_CSNK1D_ST	P35222	CTNNB1	P48730	CSNK1D	S23	R18K	18	Missense	distal	-5	no	12.113	11.676	EPSD	COSMIC	11.915	Loss
CK1_CK1_CK1-D_CSNK1D_ST	P35222	CTNNB1	P48730	CSNK1D	S23	Q28R	28	Missense	distal	5	no	12.113	12.749	EPSD	COSMIC	11.915	Up-regulation
CK1_CK1_CK1-D_CSNK1D_ST	P35222	CTNNB1	P48730	CSNK1D	S23	P16S	16	Missense	distal	-7	no	12.113	11.628	EPSD	COSMIC	11.915	Loss
CK1_CK1_CK1-D_CSNK1D_ST	P35222	CTNNB1	P48730	CSNK1D	S23	A20T	20	Missense	distal	-3	no	12.113	12.965	EPSD	COSMIC	11.915	Up-regulation
CK1_CK1_CK1-D_CSNK1D_ST	P35222	CTNNB1	P48730	CSNK1D	S23	S29T	29	Missense	distal	6	no	12.113	9.210	EPSD	COSMIC	11.915	Loss
CK1_CK1_CK1-D_CSNK1D_ST	P35222	CTNNB1	P48730	CSNK1D	S23	K19D	19	Missense	distal	-4	no	12.113	12.122	EPSD	COSMIC	11.915	Up-regulation
CK1_CK1_CK1-D_CSNK1D_ST	P35222	CTNNB1	P48730	CSNK1D	S33	A39G	39	Missense	distal	6	no	14.040	14.209	EPSD	COSMIC	11.915	Up-regulation
CK1_CK1_CK1-D_CSNK1D_ST	P35222	CTNNB1	P48730	CSNK1D	S33	G38A	38	Missense	distal	5	no	14.040	13.725	EPSD	COSMIC	11.915	Down-regulation
CK1_CK1_CK1-D_CSNK1D_ST	P35222	CTNNB1	P48730	CSNK1D	S33	T40I	40	Missense	distal	7	no	14.040	12.013	EPSD	COSMIC	11.915	Down-regulation
CK1_CK1_CK1-D_CSNK1D_ST	P35222	CTNNB1	P48730	CSNK1D	S33	I35T	35	Missense	proximal	2	no	14.040	12.426	EPSD	COSMIC	11.915	Down-regulation
CK1_CK1_CK1-D_CSNK1D_ST	P35222	CTNNB1	P48730	CSNK1D	S33	Q28E	28	Missense	distal	-5	no	14.040	14.404	EPSD	COSMIC	11.915	Up-regulation
CK1_CK1_CK1-D_CSNK1D_ST	P35222	CTNNB1	P48730	CSNK1D	S33	D32E	32	Missense	proximal	-1	no	14.040	14.555	EPSD	COSMIC	11.915	Up-regulation
CK1_CK1_CK1-D_CSNK1D_ST	P35222	CTNNB1	P48730	CSNK1D	S33	H36R	36	Missense	distal	3	no	14.040	11.959	EPSD	COSMIC	11.915	Down-regulation
CK1_CK1_CK1-D_CSNK1D_ST	P35222	CTNNB1	P48730	CSNK1D	S33	T40A	40	Missense	distal	7	no	14.040	12.245	EPSD	COSMIC	11.915	Down-regulation
CK1_CK1_CK1-D_CSNK1D_ST	P35222	CTNNB1	P48730	CSNK1D	S33	G34L	34	Missense	proximal	1	no	14.040	13.150	EPSD	COSMIC	11.915	Down-regulation
CK1_CK1_CK1-D_CSNK1D_ST	P35222	CTNNB1	P48730	CSNK1D	S33	S33L	33	Missense	central	0	yes	14.040	0.000	EPSD	COSMIC;CCLE	11.915	Loss
CK1_CK1_CK1-D_CSNK1D_ST	P35222	CTNNB1	P48730	CSNK1D	S33	S29P	29	Missense	distal	-4	no	14.040	13.575	EPSD	COSMIC	11.915	Down-regulation
CK1_CK1_CK1-D_CSNK1D_ST	P35222	CTNNB1	P48730	CSNK1D	S33	L31P	31	Missense	proximal	-2	no	14.040	16.771	EPSD	COSMIC	11.915	Up-regulation
CK1_CK1_CK1-D_CSNK1D_ST	P35222	CTNNB1	P48730	CSNK1D	S33	S37L	37	Missense	distal	4	no	14.040	14.404	EPSD	COSMIC	11.915	Up-regulation
CK1_CK1_CK1-D_CSNK1D_ST	P35222	CTNNB1	P48730	CSNK1D	S33	A39T	39	Missense	distal	6	no	14.040	12.778	EPSD	COSMIC	11.915	Down-regulation
CK1_CK1_CK1-D_CSNK1D_ST	P35222	CTNNB1	P48730	CSNK1D	S33	Q27H	27	Missense	distal	-6	no	14.040	13.031	EPSD	COSMIC	11.915	Down-regulation
CK1_CK1_CK1-D_CSNK1D_ST	P35222	CTNNB1	P48730	CSNK1D	S33	S33N	33	Missense	central	0	yes	14.040	0.000	EPSD	COSMIC	11.915	Loss
CK1_CK1_CK1-D_CSNK1D_ST	P35222	CTNNB1	P48730	CSNK1D	S33	H36Y	36	Missense	distal	3	no	14.040	11.373	EPSD	COSMIC	11.915	Loss
CK1_CK1_CK1-D_CSNK1D_ST	P35222	CTNNB1	P48730	CSNK1D	S33	S29F	29	Missense	distal	-4	no	14.040	13.709	EPSD	COSMIC	11.915	Down-regulation
CK1_CK1_CK1-D_CSNK1D_ST	P35222	CTNNB1	P48730	CSNK1D	S33	Y30C	30	Missense	distal	-3	no	14.040	13.487	EPSD	COSMIC	11.915	Down-regulation
CK1_CK1_CK1-D_CSNK1D_ST	P35222	CTNNB1	P48730	CSNK1D	S33	S29Y	29	Missense	distal	-4	no	14.040	13.203	EPSD	COSMIC	11.915	Down-regulation
CK1_CK1_CK1-D_CSNK1D_ST	P35222	CTNNB1	P48730	CSNK1D	S33	G38P	38	Missense	distal	5	no	14.040	13.974	EPSD	COSMIC	11.915	Down-regulation
CK1_CK1_CK1-D_CSNK1D_ST	P35222	CTNNB1	P48730	CSNK1D	S33	G38D	38	Missense	distal	5	no	14.040	13.583	EPSD	COSMIC	11.915	Down-regulation
CK1_CK1_CK1-D_CSNK1D_ST	P35222	CTNNB1	P48730	CSNK1D	S33	I35M	35	Missense	proximal	2	no	14.040	12.445	EPSD	COSMIC	11.915	Down-regulation
CK1_CK1_CK1-D_CSNK1D_ST	P35222	CTNNB1	P48730	CSNK1D	S33	T40S	40	Missense	distal	7	no	14.040	11.785	EPSD	COSMIC	11.915	Loss
CK1_CK1_CK1-D_CSNK1D_ST	P35222	CTNNB1	P48730	CSNK1D	S33	S29A	29	Missense	distal	-4	no	14.040	14.341	EPSD	COSMIC	11.915	Up-regulation
CK1_CK1_CK1-D_CSNK1D_ST	P35222	CTNNB1	P48730	CSNK1D	S33	G34A	34	Missense	proximal	1	no	14.040	10.444	EPSD	COSMIC	11.915	Loss
CK1_CK1_CK1-D_CSNK1D_ST	P35222	CTNNB1	P48730	CSNK1D	S33	L31W	31	Missense	proximal	-2	no	14.040	10.776	EPSD	COSMIC	11.915	Loss
CK1_CK1_CK1-D_CSNK1D_ST	P35222	CTNNB1	P48730	CSNK1D	S33	G34I	34	Missense	proximal	1	no	14.040	11.446	EPSD	COSMIC	11.915	Loss
CK1_CK1_CK1-D_CSNK1D_ST	P35222	CTNNB1	P48730	CSNK1D	S33	I35N	35	Missense	proximal	2	no	14.040	13.047	EPSD	COSMIC	11.915	Down-regulation
CK1_CK1_CK1-D_CSNK1D_ST	P35222	CTNNB1	P48730	CSNK1D	S33	D32C	32	Missense	proximal	-1	no	14.040	13.214	EPSD	COSMIC	11.915	Down-regulation
CK1_CK1_CK1-D_CSNK1D_ST	P35222	CTNNB1	P48730	CSNK1D	S33	Y30S	30	Missense	distal	-3	no	14.040	15.312	EPSD	COSMIC	11.915	Up-regulation
CK1_CK1_CK1-D_CSNK1D_ST	P35222	CTNNB1	P48730	CSNK1D	S33	L31M	31	Missense	proximal	-2	no	14.040	16.022	EPSD	COSMIC	11.915	Up-regulation
CK1_CK1_CK1-D_CSNK1D_ST	P35222	CTNNB1	P48730	CSNK1D	S33	A39V	39	Missense	distal	6	no	14.040	12.943	EPSD	COSMIC	11.915	Down-regulation
CK1_CK1_CK1-D_CSNK1D_ST	P35222	CTNNB1	P48730	CSNK1D	S33	L31Q	31	Missense	proximal	-2	no	14.040	18.428	EPSD	COSMIC	11.915	Up-regulation
CK1_CK1_CK1-D_CSNK1D_ST	P35222	CTNNB1	P48730	CSNK1D	S33	G34D	34	Missense	proximal	1	no	14.040	13.508	EPSD	COSMIC	11.915	Down-regulation
CK1_CK1_CK1-D_CSNK1D_ST	P35222	CTNNB1	P48730	CSNK1D	S33	Q26R	26	Missense	distal	-7	no	14.040	13.361	EPSD	COSMIC;GDSC;CCLE	11.915	Down-regulation
CK1_CK1_CK1-D_CSNK1D_ST	P35222	CTNNB1	P48730	CSNK1D	S33	S37T	37	Missense	distal	4	no	14.040	14.318	EPSD	COSMIC	11.915	Up-regulation
CK1_CK1_CK1-D_CSNK1D_ST	P35222	CTNNB1	P48730	CSNK1D	S33	I35K	35	Missense	proximal	2	no	14.040	12.954	EPSD	COSMIC	11.915	Down-regulation
CK1_CK1_CK1-D_CSNK1D_ST	P35222	CTNNB1	P48730	CSNK1D	S33	Q28R	28	Missense	distal	-5	no	14.040	13.263	EPSD	COSMIC	11.915	Down-regulation
CK1_CK1_CK1-D_CSNK1D_ST	P35222	CTNNB1	P48730	CSNK1D	S33	D32F	32	Missense	proximal	-1	no	14.040	14.215	EPSD	COSMIC	11.915	Up-regulation
CK1_CK1_CK1-D_CSNK1D_ST	P35222	CTNNB1	P48730	CSNK1D	S33	G38X	38	Missense	distal	5	no	14.040	13.486	EPSD	COSMIC	11.915	Down-regulation
CK1_CK1_CK1-D_CSNK1D_ST	P35222	CTNNB1	P48730	CSNK1D	S33	D32X	32	Missense	proximal	-1	no	14.040	13.613	EPSD	COSMIC	11.915	Down-regulation
CK1_CK1_CK1-D_CSNK1D_ST	P35222	CTNNB1	P48730	CSNK1D	S33	S33K	33	Missense	central	0	yes	14.040	0.000	EPSD	COSMIC	11.915	Loss
CK1_CK1_CK1-D_CSNK1D_ST	P35222	CTNNB1	P48730	CSNK1D	S33	I35V	35	Missense	proximal	2	no	14.040	12.773	EPSD	COSMIC	11.915	Down-regulation
CK1_CK1_CK1-D_CSNK1D_ST	P35222	CTNNB1	P48730	CSNK1D	S33	S29T	29	Missense	distal	-4	no	14.040	13.643	EPSD	COSMIC	11.915	Down-regulation
CK1_CK1_CK1-D_CSNK1D_ST	P35222	CTNNB1	P48730	CSNK1D	S33	G34C	34	Missense	proximal	1	no	14.040	11.544	EPSD	COSMIC	11.915	Loss
CK1_CK1_CK1-D_CSNK1D_ST	P35222	CTNNB1	P48730	CSNK1D	S33	G38S	38	Missense	distal	5	no	14.040	14.112	EPSD	COSMIC	11.915	Up-regulation
CK1_CK1_CK1-D_CSNK1D_ST	P35222	CTNNB1	P48730	CSNK1D	S33	S37V	37	Missense	distal	4	no	14.040	15.121	EPSD	COSMIC	11.915	Up-regulation
CK1_CK1_CK1-D_CSNK1D_ST	P35222	CTNNB1	P48730	CSNK1D	S33	I35F	35	Missense	proximal	2	no	14.040	12.524	EPSD	COSMIC	11.915	Down-regulation
CK1_CK1_CK1-D_CSNK1D_ST	P35222	CTNNB1	P48730	CSNK1D	S33	T40P	40	Missense	distal	7	no	14.040	12.646	EPSD	COSMIC	11.915	Down-regulation
CK1_CK1_CK1-D_CSNK1D_ST	P35222	CTNNB1	P48730	CSNK1D	T40	T41P	41	Missense	proximal	1	no	11.145	12.320	EPSD	COSMIC	11.915	Gain
CK1_CK1_CK1-D_CSNK1D_ST	P35222	CTNNB1	P48730	CSNK1D	T40	T42I	42	Missense	proximal	2	no	11.145	12.759	EPSD	COSMIC	11.915	Gain
CK1_CK1_CK1-D_CSNK1D_ST	P35222	CTNNB1	P48730	CSNK1D	T40	T42S	42	Missense	proximal	2	no	11.145	11.917	EPSD	COSMIC	11.915	Gain
CK1_CK1_CK1-D_CSNK1D_ST	P35222	CTNNB1	P48730	CSNK1D	T40	S47G	47	Missense	distal	7	no	11.145	12.012	EPSD	COSMIC	11.915	Gain
CK1_CK1_CK1-D_CSNK1D_ST	P35222	CTNNB1	P48730	CSNK1D	T40	S47N	47	Missense	distal	7	no	11.145	11.947	EPSD	COSMIC	11.915	Gain
CK1_CK1_CK1-D_CSNK1D_ST	P35222	CTNNB1	P48730	CSNK1D	T40	T42A	42	Missense	proximal	2	no	11.145	12.651	EPSD	COSMIC	11.915	Gain
CK1_CK1_CK1-D_CSNK1D_ST	P35222	CTNNB1	P48730	CSNK1D	T40	S47L	47	Missense	distal	7	no	11.145	12.951	EPSD	COSMIC	11.915	Gain
CK1_CK1_CK1-D_CSNK1D_ST	P35222	CTNNB1	P48730	CSNK1D	T40	L46M	46	Missense	distal	6	no	11.145	13.716	EPSD	COSMIC	11.915	Gain
CK1_CK1_CK1-D_CSNK1D_ST	P35222	CTNNB1	P48730	CSNK1D	T40	G34A	34	Missense	distal	-6	no	11.145	11.952	EPSD	COSMIC	11.915	Gain
CK1_CK1_CK1-D_CSNK1D_ST	P35222	CTNNB1	P48730	CSNK1D	T40	S47T	47	Missense	distal	7	no	11.145	13.400	EPSD	COSMIC	11.915	Gain
CK1_CK1_CK1-D_CSNK1D_ST	P35222	CTNNB1	P48730	CSNK1D	T40	I35N	35	Missense	distal	-5	no	11.145	13.984	EPSD	COSMIC	11.915	Gain
CK1_CK1_CK1-D_CSNK1D_ST	P35222	CTNNB1	P48730	CSNK1D	T40	I35V	35	Missense	distal	-5	no	11.145	13.208	EPSD	COSMIC	11.915	Gain
CK1_CK1_CK1-D_CSNK1D_ST	P35222	CTNNB1	P48730	CSNK1D	T40	S47Y	47	Missense	distal	7	no	11.145	12.004	EPSD	COSMIC	11.915	Gain
CK1_CK1_CK1-D_CSNK1D_ST	P35222	CTNNB1	P48730	CSNK1D	T41	S45T	45	Missense	distal	4	no	11.711	11.989	EPSD	COSMIC	11.915	Gain
CK1_CK1_CK1-D_CSNK1D_ST	P35222	CTNNB1	P48730	CSNK1D	T41	P44S	44	Missense	distal	3	no	11.711	14.479	EPSD	COSMIC	11.915	Gain
CK1_CK1_CK1-D_CSNK1D_ST	P35222	CTNNB1	P48730	CSNK1D	T41	T40I	40	Missense	proximal	-1	no	11.711	13.334	EPSD	COSMIC	11.915	Gain
CK1_CK1_CK1-D_CSNK1D_ST	P35222	CTNNB1	P48730	CSNK1D	T41	P44A	44	Missense	distal	3	no	11.711	14.157	EPSD	COSMIC	11.915	Gain
CK1_CK1_CK1-D_CSNK1D_ST	P35222	CTNNB1	P48730	CSNK1D	T41	H36R	36	Missense	distal	-5	no	11.711	13.561	EPSD	COSMIC	11.915	Gain
CK1_CK1_CK1-D_CSNK1D_ST	P35222	CTNNB1	P48730	CSNK1D	T41	T40A	40	Missense	proximal	-1	no	11.711	13.065	EPSD	COSMIC	11.915	Gain
CK1_CK1_CK1-D_CSNK1D_ST	P35222	CTNNB1	P48730	CSNK1D	T41	P44L	44	Missense	distal	3	no	11.711	12.691	EPSD	COSMIC	11.915	Gain
CK1_CK1_CK1-D_CSNK1D_ST	P35222	CTNNB1	P48730	CSNK1D	T41	G48V	48	Missense	distal	7	no	11.711	12.226	EPSD	COSMIC	11.915	Gain
CK1_CK1_CK1-D_CSNK1D_ST	P35222	CTNNB1	P48730	CSNK1D	T41	A39T	39	Missense	proximal	-2	no	11.711	12.052	EPSD	COSMIC	11.915	Gain
CK1_CK1_CK1-D_CSNK1D_ST	P35222	CTNNB1	P48730	CSNK1D	T41	H36Y	36	Missense	distal	-5	no	11.711	12.492	EPSD	COSMIC	11.915	Gain
CK1_CK1_CK1-D_CSNK1D_ST	P35222	CTNNB1	P48730	CSNK1D	T41	L46P	46	Missense	distal	5	no	11.711	12.831	EPSD	COSMIC	11.915	Gain
CK1_CK1_CK1-D_CSNK1D_ST	P35222	CTNNB1	P48730	CSNK1D	T41	G38D	38	Missense	distal	-3	no	11.711	12.692	EPSD	COSMIC	11.915	Gain
CK1_CK1_CK1-D_CSNK1D_ST	P35222	CTNNB1	P48730	CSNK1D	T41	L46V	46	Missense	distal	5	no	11.711	12.065	EPSD	COSMIC	11.915	Gain
CK1_CK1_CK1-D_CSNK1D_ST	P35222	CTNNB1	P48730	CSNK1D	T41	T40S	40	Missense	proximal	-1	no	11.711	12.254	EPSD	COSMIC	11.915	Gain
CK1_CK1_CK1-D_CSNK1D_ST	P35222	CTNNB1	P48730	CSNK1D	T41	L46M	46	Missense	distal	5	no	11.711	12.857	EPSD	COSMIC	11.915	Gain
CK1_CK1_CK1-D_CSNK1D_ST	P35222	CTNNB1	P48730	CSNK1D	T41	I35N	35	Missense	distal	-6	no	11.711	12.420	EPSD	COSMIC	11.915	Gain
CK1_CK1_CK1-D_CSNK1D_ST	P35222	CTNNB1	P48730	CSNK1D	T41	T42Q	42	Missense	proximal	1	no	11.711	12.426	EPSD	COSMIC	11.915	Gain
CK1_CK1_CK1-D_CSNK1D_ST	P35222	CTNNB1	P48730	CSNK1D	T41	I35K	35	Missense	distal	-6	no	11.711	12.229	EPSD	COSMIC	11.915	Gain
CK1_CK1_CK1-D_CSNK1D_ST	P35222	CTNNB1	P48730	CSNK1D	T41	L46Q	46	Missense	distal	5	no	11.711	12.002	EPSD	COSMIC	11.915	Gain
CK1_CK1_CK1-D_CSNK1D_ST	P35222	CTNNB1	P48730	CSNK1D	T41	I35V	35	Missense	distal	-6	no	11.711	12.615	EPSD	COSMIC	11.915	Gain
CK1_CK1_CK1-D_CSNK1D_ST	P35222	CTNNB1	P48730	CSNK1D	T41	S45X	45	Missense	distal	4	no	11.711	12.013	EPSD	COSMIC	11.915	Gain
CK1_CK1_CK1-D_CSNK1D_ST	P35222	CTNNB1	P48730	CSNK1D	T41	G38S	38	Missense	distal	-3	no	11.711	12.459	EPSD	COSMIC	11.915	Gain
CK1_CK1_CK1-D_CSNK1D_ST	P35222	CTNNB1	P48730	CSNK1D	T41	I35F	35	Missense	distal	-6	no	11.711	12.041	EPSD	COSMIC	11.915	Gain
CK1_CK1_CK1-D_CSNK1D_ST	P35222	CTNNB1	P48730	CSNK1D	T41	T40P	40	Missense	proximal	-1	no	11.711	12.075	EPSD	COSMIC	11.915	Gain
CK1_CK1_CK1-D_CSNK1D_ST	P35222	CTNNB1	P48730	CSNK1D	T42	A43V	43	Missense	proximal	1	no	9.971	13.672	EPSD	COSMIC	11.915	Gain
CK1_CK1_CK1-D_CSNK1D_ST	P35222	CTNNB1	P48730	CSNK1D	T42	A43P	43	Missense	proximal	1	no	9.971	12.726	EPSD	COSMIC	11.915	Gain
CK1_CK1_CK1-D_CSNK1D_ST	P35222	CTNNB1	P48730	CSNK1D	S45	P44S	44	Missense	proximal	-1	no	13.837	14.016	PhosphoSitePlus	COSMIC	11.915	Up-regulation
CK1_CK1_CK1-D_CSNK1D_ST	P35222	CTNNB1	P48730	CSNK1D	S45	A43V	43	Missense	proximal	-2	no	13.837	11.137	PhosphoSitePlus	COSMIC	11.915	Loss
CK1_CK1_CK1-D_CSNK1D_ST	P35222	CTNNB1	P48730	CSNK1D	S45	G48D	48	Missense	distal	3	no	13.837	13.959	PhosphoSitePlus	COSMIC	11.915	Up-regulation
CK1_CK1_CK1-D_CSNK1D_ST	P35222	CTNNB1	P48730	CSNK1D	S45	A39G	39	Missense	distal	-6	no	13.837	13.030	PhosphoSitePlus	COSMIC	11.915	Down-regulation
CK1_CK1_CK1-D_CSNK1D_ST	P35222	CTNNB1	P48730	CSNK1D	S45	N51T	51	Missense	distal	6	no	13.837	11.378	PhosphoSitePlus	COSMIC	11.915	Loss
CK1_CK1_CK1-D_CSNK1D_ST	P35222	CTNNB1	P48730	CSNK1D	S45	P52L	52	Missense	distal	7	no	13.837	14.782	PhosphoSitePlus	COSMIC	11.915	Up-regulation
CK1_CK1_CK1-D_CSNK1D_ST	P35222	CTNNB1	P48730	CSNK1D	S45	N51S	51	Missense	distal	6	no	13.837	14.281	PhosphoSitePlus	COSMIC	11.915	Up-regulation
CK1_CK1_CK1-D_CSNK1D_ST	P35222	CTNNB1	P48730	CSNK1D	S45	G38A	38	Missense	distal	-7	no	13.837	13.659	PhosphoSitePlus	COSMIC	11.915	Down-regulation
CK1_CK1_CK1-D_CSNK1D_ST	P35222	CTNNB1	P48730	CSNK1D	S45	T40I	40	Missense	distal	-5	no	13.837	14.129	PhosphoSitePlus	COSMIC	11.915	Up-regulation
CK1_CK1_CK1-D_CSNK1D_ST	P35222	CTNNB1	P48730	CSNK1D	S45	P44A	44	Missense	proximal	-1	no	13.837	14.827	PhosphoSitePlus	COSMIC	11.915	Up-regulation
CK1_CK1_CK1-D_CSNK1D_ST	P35222	CTNNB1	P48730	CSNK1D	S45	T41P	41	Missense	distal	-4	no	13.837	13.769	PhosphoSitePlus	COSMIC	11.915	Down-regulation
CK1_CK1_CK1-D_CSNK1D_ST	P35222	CTNNB1	P48730	CSNK1D	S45	K49R	49	Missense	distal	4	no	13.837	13.841	PhosphoSitePlus	COSMIC	11.915	Up-regulation
CK1_CK1_CK1-D_CSNK1D_ST	P35222	CTNNB1	P48730	CSNK1D	S45	T42R	42	Missense	distal	-3	no	13.837	14.332	PhosphoSitePlus	COSMIC	11.915	Up-regulation
CK1_CK1_CK1-D_CSNK1D_ST	P35222	CTNNB1	P48730	CSNK1D	S45	S45A	45	Missense	central	0	yes	13.837	0.000	PhosphoSitePlus	COSMIC	11.915	Loss
CK1_CK1_CK1-D_CSNK1D_ST	P35222	CTNNB1	P48730	CSNK1D	S45	G48S	48	Missense	distal	3	no	13.837	14.759	PhosphoSitePlus	COSMIC	11.915	Up-regulation
CK1_CK1_CK1-D_CSNK1D_ST	P35222	CTNNB1	P48730	CSNK1D	S45	T40A	40	Missense	distal	-5	no	13.837	15.698	PhosphoSitePlus	COSMIC	11.915	Up-regulation
CK1_CK1_CK1-D_CSNK1D_ST	P35222	CTNNB1	P48730	CSNK1D	S45	A43T	43	Missense	proximal	-2	no	13.837	14.178	PhosphoSitePlus	COSMIC	11.915	Up-regulation
CK1_CK1_CK1-D_CSNK1D_ST	P35222	CTNNB1	P48730	CSNK1D	S45	P44L	44	Missense	proximal	-1	no	13.837	14.131	PhosphoSitePlus	COSMIC	11.915	Up-regulation
CK1_CK1_CK1-D_CSNK1D_ST	P35222	CTNNB1	P48730	CSNK1D	S45	T42I	42	Missense	distal	-3	no	13.837	7.448	PhosphoSitePlus	COSMIC	11.915	Loss
CK1_CK1_CK1-D_CSNK1D_ST	P35222	CTNNB1	P48730	CSNK1D	S45	T42S	42	Missense	distal	-3	no	13.837	15.520	PhosphoSitePlus	COSMIC	11.915	Up-regulation
CK1_CK1_CK1-D_CSNK1D_ST	P35222	CTNNB1	P48730	CSNK1D	S45	T42K	42	Missense	distal	-3	no	13.837	12.225	PhosphoSitePlus	COSMIC	11.915	Down-regulation
CK1_CK1_CK1-D_CSNK1D_ST	P35222	CTNNB1	P48730	CSNK1D	S45	S47G	47	Missense	proximal	2	no	13.837	14.206	PhosphoSitePlus	COSMIC	11.915	Up-regulation
CK1_CK1_CK1-D_CSNK1D_ST	P35222	CTNNB1	P48730	CSNK1D	S45	G48V	48	Missense	distal	3	no	13.837	11.259	PhosphoSitePlus	COSMIC	11.915	Loss
CK1_CK1_CK1-D_CSNK1D_ST	P35222	CTNNB1	P48730	CSNK1D	S45	S47N	47	Missense	proximal	2	no	13.837	13.686	PhosphoSitePlus	COSMIC	11.915	Down-regulation
CK1_CK1_CK1-D_CSNK1D_ST	P35222	CTNNB1	P48730	CSNK1D	S45	A39T	39	Missense	distal	-6	no	13.837	12.462	PhosphoSitePlus	COSMIC	11.915	Down-regulation
CK1_CK1_CK1-D_CSNK1D_ST	P35222	CTNNB1	P48730	CSNK1D	S45	K49T	49	Missense	distal	4	no	13.837	13.874	PhosphoSitePlus	COSMIC	11.915	Up-regulation
CK1_CK1_CK1-D_CSNK1D_ST	P35222	CTNNB1	P48730	CSNK1D	S45	G50D	50	Missense	distal	5	no	13.837	13.380	PhosphoSitePlus	COSMIC	11.915	Down-regulation
CK1_CK1_CK1-D_CSNK1D_ST	P35222	CTNNB1	P48730	CSNK1D	S45	A43P	43	Missense	proximal	-2	no	13.837	11.682	PhosphoSitePlus	COSMIC	11.915	Loss
CK1_CK1_CK1-D_CSNK1D_ST	P35222	CTNNB1	P48730	CSNK1D	S45	L46P	46	Missense	proximal	1	no	13.837	13.886	PhosphoSitePlus	COSMIC	11.915	Up-regulation
CK1_CK1_CK1-D_CSNK1D_ST	P35222	CTNNB1	P48730	CSNK1D	S45	G38P	38	Missense	distal	-7	no	13.837	13.667	PhosphoSitePlus	COSMIC	11.915	Down-regulation
CK1_CK1_CK1-D_CSNK1D_ST	P35222	CTNNB1	P48730	CSNK1D	S45	G38D	38	Missense	distal	-7	no	13.837	13.055	PhosphoSitePlus	COSMIC	11.915	Down-regulation
CK1_CK1_CK1-D_CSNK1D_ST	P35222	CTNNB1	P48730	CSNK1D	S45	T42A	42	Missense	distal	-3	no	13.837	12.984	PhosphoSitePlus	COSMIC	11.915	Down-regulation
CK1_CK1_CK1-D_CSNK1D_ST	P35222	CTNNB1	P48730	CSNK1D	S45	L46V	46	Missense	proximal	1	no	13.837	14.832	PhosphoSitePlus	COSMIC	11.915	Up-regulation
CK1_CK1_CK1-D_CSNK1D_ST	P35222	CTNNB1	P48730	CSNK1D	S45	S47L	47	Missense	proximal	2	no	13.837	12.319	PhosphoSitePlus	COSMIC	11.915	Down-regulation
CK1_CK1_CK1-D_CSNK1D_ST	P35222	CTNNB1	P48730	CSNK1D	S45	T40S	40	Missense	distal	-5	no	13.837	15.271	PhosphoSitePlus	COSMIC	11.915	Up-regulation
CK1_CK1_CK1-D_CSNK1D_ST	P35222	CTNNB1	P48730	CSNK1D	S45	K49L	49	Missense	distal	4	no	13.837	13.960	PhosphoSitePlus	COSMIC	11.915	Up-regulation
CK1_CK1_CK1-D_CSNK1D_ST	P35222	CTNNB1	P48730	CSNK1D	S45	L46M	46	Missense	proximal	1	no	13.837	12.514	PhosphoSitePlus	COSMIC	11.915	Down-regulation
CK1_CK1_CK1-D_CSNK1D_ST	P35222	CTNNB1	P48730	CSNK1D	S45	S47T	47	Missense	proximal	2	no	13.837	13.065	PhosphoSitePlus	COSMIC	11.915	Down-regulation
CK1_CK1_CK1-D_CSNK1D_ST	P35222	CTNNB1	P48730	CSNK1D	S45	T41S	41	Missense	distal	-4	no	13.837	14.234	PhosphoSitePlus	COSMIC	11.915	Up-regulation
CK1_CK1_CK1-D_CSNK1D_ST	P35222	CTNNB1	P48730	CSNK1D	S45	T42Q	42	Missense	distal	-3	no	13.837	12.312	PhosphoSitePlus	COSMIC	11.915	Down-regulation
CK1_CK1_CK1-D_CSNK1D_ST	P35222	CTNNB1	P48730	CSNK1D	S45	S47C	47	Missense	proximal	2	no	13.837	13.002	PhosphoSitePlus	COSMIC	11.915	Down-regulation
CK1_CK1_CK1-D_CSNK1D_ST	P35222	CTNNB1	P48730	CSNK1D	S45	K49E	49	Missense	distal	4	no	13.837	13.369	PhosphoSitePlus	COSMIC	11.915	Down-regulation
CK1_CK1_CK1-D_CSNK1D_ST	P35222	CTNNB1	P48730	CSNK1D	S45	S47R	47	Missense	proximal	2	no	13.837	13.603	PhosphoSitePlus	COSMIC	11.915	Down-regulation
CK1_CK1_CK1-D_CSNK1D_ST	P35222	CTNNB1	P48730	CSNK1D	S45	A39V	39	Missense	distal	-6	no	13.837	13.524	PhosphoSitePlus	COSMIC	11.915	Down-regulation
CK1_CK1_CK1-D_CSNK1D_ST	P35222	CTNNB1	P48730	CSNK1D	S45	S45E	45	Missense	central	0	yes	13.837	0.000	PhosphoSitePlus	COSMIC	11.915	Loss
CK1_CK1_CK1-D_CSNK1D_ST	P35222	CTNNB1	P48730	CSNK1D	S45	G50S	50	Missense	distal	5	no	13.837	13.909	PhosphoSitePlus	COSMIC	11.915	Up-regulation
CK1_CK1_CK1-D_CSNK1D_ST	P35222	CTNNB1	P48730	CSNK1D	S45	S45N	45	Missense	central	0	yes	13.837	0.000	PhosphoSitePlus	COSMIC	11.915	Loss
CK1_CK1_CK1-D_CSNK1D_ST	P35222	CTNNB1	P48730	CSNK1D	S45	G38X	38	Missense	distal	-7	no	13.837	12.624	PhosphoSitePlus	COSMIC	11.915	Down-regulation
CK1_CK1_CK1-D_CSNK1D_ST	P35222	CTNNB1	P48730	CSNK1D	S45	L46Q	46	Missense	proximal	1	no	13.837	13.427	PhosphoSitePlus	COSMIC	11.915	Down-regulation
CK1_CK1_CK1-D_CSNK1D_ST	P35222	CTNNB1	P48730	CSNK1D	S45	S45X	45	Missense	central	0	yes	13.837	0.000	PhosphoSitePlus	COSMIC	11.915	Loss
CK1_CK1_CK1-D_CSNK1D_ST	P35222	CTNNB1	P48730	CSNK1D	S45	G38S	38	Missense	distal	-7	no	13.837	13.182	PhosphoSitePlus	COSMIC	11.915	Down-regulation
CK1_CK1_CK1-D_CSNK1D_ST	P35222	CTNNB1	P48730	CSNK1D	S45	P44I	44	Missense	proximal	-1	no	13.837	15.096	PhosphoSitePlus	COSMIC	11.915	Up-regulation
CK1_CK1_CK1-D_CSNK1D_ST	P35222	CTNNB1	P48730	CSNK1D	S45	S47I	47	Missense	proximal	2	no	13.837	14.678	PhosphoSitePlus	COSMIC	11.915	Up-regulation
CK1_CK1_CK1-D_CSNK1D_ST	P35222	CTNNB1	P48730	CSNK1D	S45	S47Y	47	Missense	proximal	2	no	13.837	11.937	PhosphoSitePlus	COSMIC	11.915	Down-regulation
CK1_CK1_CK1-D_CSNK1D_ST	P35222	CTNNB1	P48730	CSNK1D	S45	T40P	40	Missense	distal	-5	no	13.837	15.265	PhosphoSitePlus	COSMIC	11.915	Up-regulation
CK1_CK1_CK1-D_CSNK1D_ST	P35222	CTNNB1	P48730	CSNK1D	S47	P44S	44	Missense	distal	-3	no	9.841	13.841	EPSD	COSMIC	11.915	Gain
CK1_CK1_CK1-D_CSNK1D_ST	P35222	CTNNB1	P48730	CSNK1D	S47	T42Q	42	Missense	distal	-5	no	9.841	11.941	EPSD	COSMIC	11.915	Gain
CK1_CK1_CK1-D_CSNK1D_ST	P35222	CTNNB1	P48730	CSNK1D	T59	P52L	52	Missense	distal	-7	no	14.261	12.076	EPSD	COSMIC	11.915	Down-regulation
CK1_CK1_CK1-D_CSNK1D_ST	P35222	CTNNB1	P48730	CSNK1D	T59	E53K	53	Missense	distal	-6	no	14.261	13.461	EPSD	COSMIC	11.915	Down-regulation
CK1_CK1_CK1-D_CSNK1D_ST	P35222	CTNNB1	P48730	CSNK1D	T59	E55G	55	Missense	distal	-4	no	14.261	14.072	EPSD	COSMIC	11.915	Down-regulation
CK1_CK1_CK1-D_CSNK1D_ST	P35222	CTNNB1	P48730	CSNK1D	T59	E54K	54	Missense	distal	-5	no	14.261	12.683	EPSD	COSMIC	11.915	Down-regulation
CK1_CK1_CK1-D_CSNK1D_ST	P35222	CTNNB1	P48730	CSNK1D	T59	V62G	62	Missense	distal	3	no	14.261	16.838	EPSD	COSMIC	11.915	Up-regulation
CK1_CK1_CK1-D_CSNK1D_ST	P35222	CTNNB1	P48730	CSNK1D	T59	Q61R	61	Missense	proximal	2	no	14.261	14.150	EPSD	COSMIC	11.915	Down-regulation
CK1_CK1_CK1-D_CSNK1D_ST	P35222	CTNNB1	P48730	CSNK1D	T59	D58N	58	Missense	proximal	-1	no	14.261	14.258	EPSD	COSMIC	11.915	Down-regulation
CK1_CK1_CK1-D_CSNK1D_ST	P35222	CTNNB1	P48730	CSNK1D	T59	E54G	54	Missense	distal	-5	no	14.261	13.446	EPSD	COSMIC	11.915	Down-regulation
CK1_CK1_CK1-D_CSNK1D_ST	P35222	CTNNB1	P48730	CSNK1D	T59	V57A	57	Missense	proximal	-2	no	14.261	16.961	EPSD	COSMIC	11.915	Up-regulation
CK1_CK1_CK1-D_CSNK1D_ST	P35222	CTNNB1	P48730	CSNK1D	T59	S60C	60	Missense	proximal	1	no	14.261	14.925	EPSD	COSMIC	11.915	Up-regulation
CK1_CK1_CK1-D_CSNK1D_ST	P35222	CTNNB1	P48730	CSNK1D	T59	V57M	57	Missense	proximal	-2	no	14.261	14.057	EPSD	COSMIC	11.915	Down-regulation
CK1_CK1_CK1-D_CSNK1D_ST	P35222	CTNNB1	P48730	CSNK1D	T59	Q61L	61	Missense	proximal	2	no	14.261	12.865	EPSD	COSMIC	11.915	Down-regulation
CK1_CK1_CK1-D_CSNK1D_ST	P35222	CTNNB1	P48730	CSNK1D	T59	E55L	55	Missense	distal	-4	no	14.261	14.096	EPSD	COSMIC	11.915	Down-regulation
CK1_CK1_CK1-D_CSNK1D_ST	P35222	CTNNB1	P48730	CSNK1D	T59	W66L	66	Missense	distal	7	no	14.261	12.731	EPSD	COSMIC	11.915	Down-regulation
CK1_CK1_CK1-D_CSNK1D_ST	P35222	CTNNB1	P48730	CSNK1D	T59	E65K	65	Missense	distal	6	no	14.261	12.462	EPSD	COSMIC	11.915	Down-regulation
CK1_CK1_CK1-D_CSNK1D_ST	P35222	CTNNB1	P48730	CSNK1D	T59	L63M	63	Missense	distal	4	no	14.261	14.182	EPSD	COSMIC	11.915	Down-regulation
CK1_CK1_CK1-D_CSNK1D_ST	P35222	CTNNB1	P48730	CSNK1D	T59	D56N	56	Missense	distal	-3	no	14.261	11.818	EPSD	COSMIC	11.915	Loss
CK1_CK1_CK1-D_CSNK1D_ST	P35222	CTNNB1	P48730	CSNK1D	T59	E55D	55	Missense	distal	-4	no	14.261	14.120	EPSD	COSMIC	11.915	Down-regulation
CK1_CK1_CK1-D_CSNK1D_ST	P35222	CTNNB1	P48730	CSNK1D	T59	T59A	59	Missense	central	0	yes	14.261	0.000	EPSD	COSMIC	11.915	Loss
CK1_CK1_CK1-D_CSNK1D_ST	P35222	CTNNB1	P48730	CSNK1D	S179	H176R	176	Missense	distal	-3	no	13.351	13.869	EPSD	COSMIC	11.915	Up-regulation
CK1_CK1_CK1-D_CSNK1D_ST	P35222	CTNNB1	P48730	CSNK1D	S179	A183S	183	Missense	distal	4	no	13.351	13.520	EPSD	COSMIC	11.915	Up-regulation
CK1_CK1_CK1-D_CSNK1D_ST	P35222	CTNNB1	P48730	CSNK1D	S179	Q177P	177	Missense	proximal	-2	no	13.351	11.694	EPSD	COSMIC	11.915	Loss
CK1_CK1_CK1-D_CSNK1D_ST	P35222	CTNNB1	P48730	CSNK1D	S179	V175I	175	Missense	distal	-4	no	13.351	13.797	EPSD	COSMIC	11.915	Up-regulation
CK1_CK1_CK1-D_CSNK1D_ST	P35222	CTNNB1	P48730	CSNK1D	S179	A183T	183	Missense	distal	4	no	13.351	13.798	EPSD	COSMIC	11.915	Up-regulation
CK1_CK1_CK1-D_CSNK1D_ST	P35222	CTNNB1	P48730	CSNK1D	S179	E182D	182	Missense	distal	3	no	13.351	13.030	EPSD	COSMIC	11.915	Down-regulation
CK1_CK1_CK1-D_CSNK1D_ST	P35222	CTNNB1	P48730	CSNK1D	S179	R185K	185	Missense	distal	6	no	13.351	14.623	EPSD	COSMIC	11.915	Up-regulation
CK1_CK1_CK1-D_CSNK1D_ST	P35222	CTNNB1	P48730	CSNK1D	T201	I198L	198	Missense	distal	-3	no	6.197	12.063	EPSD	COSMIC	11.915	Gain
CK1_CK1_CK1-D_CSNK1D_ST	P35222	CTNNB1	P48730	CSNK1D	T393	K394N	394	Missense	proximal	1	no	10.129	12.285	EPSD	COSMIC	11.915	Gain
CK1_CK1_CK1-D_CSNK1D_ST	P35222	CTNNB1	P48730	CSNK1D	T547	T551K	551	Missense	distal	4	no	12.866	12.828	EPSD	COSMIC	11.915	Down-regulation
CK1_CK1_CK1-D_CSNK1D_ST	P35222	CTNNB1	P48730	CSNK1D	T547	R549C	549	Missense	proximal	2	no	12.866	12.264	EPSD	COSMIC	11.915	Down-regulation
CK1_CK1_CK1-D_CSNK1D_ST	P35222	CTNNB1	P48730	CSNK1D	T547	Q545K	545	Missense	proximal	-2	no	12.866	11.904	EPSD	COSMIC	11.915	Loss
CK1_CK1_CK1-D_CSNK1D_ST	P35222	CTNNB1	P48730	CSNK1D	T547	A543T	543	Missense	distal	-4	no	12.866	12.168	EPSD	COSMIC	11.915	Down-regulation
CK1_CK1_CK1-D_CSNK1D_ST	P35222	CTNNB1	P48730	CSNK1D	T547	R550H	550	Missense	distal	3	no	12.866	14.947	EPSD	COSMIC	11.915	Up-regulation
CK1_CK1_CK1-D_CSNK1D_ST	P35222	CTNNB1	P48730	CSNK1D	T547	L540F	540	Missense	distal	-7	no	12.866	13.485	EPSD	COSMIC	11.915	Up-regulation
CK1_CK1_CK1-D_CSNK1D_ST	P35222	CTNNB1	P48730	CSNK1D	T547	R550L	550	Missense	distal	3	no	12.866	14.321	EPSD	COSMIC	11.915	Up-regulation
CK1_CK1_CK1-D_CSNK1D_ST	P35222	CTNNB1	P48730	CSNK1D	T547	A543V	543	Missense	distal	-4	no	12.866	12.099	EPSD	COSMIC	11.915	Down-regulation
CK1_CK1_CK1-D_CSNK1D_ST	P35222	CTNNB1	P48730	CSNK1D	T547	D546E	546	Missense	proximal	-1	no	12.866	13.381	EPSD	COSMIC	11.915	Up-regulation
CK1_CK1_CK1-D_CSNK1D_ST	P35222	CTNNB1	P48730	CSNK1D	T547	S552F	552	Missense	distal	5	no	12.866	12.386	EPSD	COSMIC	11.915	Down-regulation
CK1_CK1_CK1-D_CSNK1D_ST	P35222	CTNNB1	P48730	CSNK1D	T547	G554D	554	Missense	distal	7	no	12.866	13.069	EPSD	COSMIC	11.915	Up-regulation
CK1_CK1_CK1-D_CSNK1D_ST	P35222	CTNNB1	P48730	CSNK1D	T547	R550Q	550	Missense	distal	3	no	12.866	14.660	EPSD	COSMIC	11.915	Up-regulation
CK1_CK1_CK1-D_CSNK1D_ST	P35222	CTNNB1	P48730	CSNK1D	T547	T551I	551	Missense	distal	4	no	12.866	12.518	EPSD	COSMIC	11.915	Down-regulation
CK1_CK1_CK1-D_CSNK1D_ST	P35222	CTNNB1	P48730	CSNK1D	T653	T653R	653	Missense	central	0	yes	13.053	0.000	EPSD	COSMIC	11.915	Loss
CK1_CK1_CK1-D_CSNK1D_ST	P35222	CTNNB1	P48730	CSNK1D	T653	A657T	657	Missense	distal	4	no	13.053	13.501	EPSD	COSMIC	11.915	Up-regulation
CK1_CK1_CK1-D_CSNK1D_ST	P35222	CTNNB1	P48730	CSNK1D	T653	R647G	647	Missense	distal	-6	no	13.053	12.635	EPSD	COSMIC	11.915	Down-regulation
CK1_CK1_CK1-D_CSNK1D_ST	P35222	CTNNB1	P48730	CSNK1D	T653	A652V	652	Missense	proximal	-1	no	13.053	12.507	EPSD	COSMIC	11.915	Down-regulation
CK1_CK1_CK1-D_CSNK1D_ST	P35222	CTNNB1	P48730	CSNK1D	T653	S646F	646	Missense	distal	-7	no	13.053	11.973	EPSD	COSMIC	11.915	Down-regulation
CK1_CK1_CK1-D_CSNK1D_ST	P35222	CTNNB1	P48730	CSNK1D	T653	V658F	658	Missense	distal	5	no	13.053	13.477	EPSD	COSMIC;GDSC	11.915	Up-regulation
CK1_CK1_CK1-D_CSNK1D_ST	P35222	CTNNB1	P48730	CSNK1D	T653	L659S	659	Missense	distal	6	no	13.053	14.738	EPSD	COSMIC	11.915	Up-regulation
CK1_CK1_CK1-D_CSNK1D_ST	P35222	CTNNB1	P48730	CSNK1D	T653	V651F	651	Missense	proximal	-2	no	13.053	12.746	EPSD	COSMIC	11.915	Down-regulation
CK1_CK1_CK1-D_CSNK1D_ST	P35222	CTNNB1	P48730	CSNK1D	T653	A656T	656	Missense	distal	3	no	13.053	11.839	EPSD	COSMIC	11.915	Loss
CK1_CK1_CK1-D_CSNK1D_ST	P35222	CTNNB1	P48730	CSNK1D	S675	R673H	673	Missense	proximal	-2	no	11.157	13.305	EPSD	COSMIC	11.915	Gain
CK1_CK1_CK1-D_CSNK1D_ST	P35222	CTNNB1	P48730	CSNK1D	S675	R673C	673	Missense	proximal	-2	no	11.157	12.849	EPSD	COSMIC	11.915	Gain
CK1_CK1_CK1-D_CSNK1D_ST	Q14511	NEDD9	P48730	CSNK1D	T268	P265S	265	Missense	distal	-3	no	8.832	12.832	EPSD	COSMIC	11.915	Gain
CK1_CK1_CK1-D_CSNK1D_ST	Q14511	NEDD9	P48730	CSNK1D	S298	P304L	304	Missense	distal	6	no	12.728	13.335	EPSD	COSMIC	11.915	Up-regulation
CK1_CK1_CK1-D_CSNK1D_ST	Q14511	NEDD9	P48730	CSNK1D	S298	R292Q	292	Missense	distal	-6	no	12.728	12.395	EPSD	COSMIC;CCLE	11.915	Down-regulation
CK1_CK1_CK1-D_CSNK1D_ST	Q14511	NEDD9	P48730	CSNK1D	S369	R367Q	367	Missense	proximal	-2	no	10.518	12.001	EPSD	COSMIC	11.915	Gain
CK1_CK1_CK1-D_CSNK1D_ST	Q14511	NEDD9	P48730	CSNK1D	S369	N366S	366	Missense	distal	-3	no	10.518	12.728	EPSD	COSMIC	11.915	Gain
CK1_CK1_CK1-D_CSNK1D_ST	Q14511	NEDD9	P48730	CSNK1D	S372	R367Q	367	Missense	distal	-5	no	11.754	12.531	EPSD	COSMIC	11.915	Gain
CK1_CK1_CK1-D_CSNK1D_ST	Q14511	NEDD9	P48730	CSNK1D	S372	N366S	366	Missense	distal	-6	no	11.754	12.105	EPSD	COSMIC	11.915	Gain
CK1_CK1_CK1-D_CSNK1D_ST	Q14511	NEDD9	P48730	CSNK1D	T373	T376S	376	Missense	distal	3	no	10.653	12.189	EPSD	COSMIC	11.915	Gain
CK1_CK1_CK1-D_CSNK1D_ST	Q14511	NEDD9	P48730	CSNK1D	S375	R377L	377	Missense	proximal	2	no	15.892	14.607	EPSD	COSMIC	11.915	Down-regulation
CK1_CK1_CK1-D_CSNK1D_ST	Q14511	NEDD9	P48730	CSNK1D	S375	T376S	376	Missense	proximal	1	no	15.892	14.748	EPSD	COSMIC	11.915	Down-regulation
CK1_CK1_CK1-D_CSNK1D_ST	Q14511	NEDD9	P48730	CSNK1D	S395	S395F	395	Missense	central	0	yes	14.119	0.000	EPSD	COSMIC	11.915	Loss
CK1_CK1_CK1-D_CSNK1D_ST	Q14511	NEDD9	P48730	CSNK1D	S618	G620S	620	Missense	proximal	2	no	14.820	14.450	EPSD	COSMIC	11.915	Down-regulation
CK1_CK1_CK1-D_CSNK1D_ST	Q14511	NEDD9	P48730	CSNK1D	S621	G620S	620	Missense	proximal	-1	no	13.835	13.895	EPSD	COSMIC	11.915	Up-regulation
CK1_CK1_CK1-D_CSNK1D_ST	Q14511	NEDD9	P48730	CSNK1D	T804	T804I	804	Missense	central	0	yes	15.147	0.000	EPSD;PhosphoSitePlus	COSMIC	11.915	Loss
CK1_CK1_CK1-D_CSNK1D_ST	Q14511	NEDD9	P48730	CSNK1D	T804	M810T	810	Missense	distal	6	no	15.147	11.359	EPSD;PhosphoSitePlus	COSMIC	11.915	Loss
CK1_CK1_CK1-D_CSNK1D_ST	Q14511	NEDD9	P48730	CSNK1D	T804	P802S	802	Missense	proximal	-2	no	15.147	16.036	EPSD;PhosphoSitePlus	COSMIC	11.915	Up-regulation
CK1_CK1_CK1-D_CSNK1D_ST	Q14511	NEDD9	P48730	CSNK1D	T804	A806T	806	Missense	proximal	2	no	15.147	13.641	EPSD;PhosphoSitePlus	COSMIC	11.915	Down-regulation
CK1_CK1_CK1-D_CSNK1D_ST	P46937	YAP1	P48730	CSNK1D	T119	A125G	125	Missense	distal	6	no	13.730	13.899	EPSD	COSMIC	11.915	Up-regulation
CK1_CK1_CK1-D_CSNK1D_ST	P46937	YAP1	P48730	CSNK1D	T143	T145S	145	Missense	proximal	2	no	11.142	11.915	EPSD	COSMIC	11.915	Gain
CK1_CK1_CK1-D_CSNK1D_ST	P46937	YAP1	P48730	CSNK1D	T154	P151A	151	Missense	distal	-3	no	10.570	12.035	EPSD	COSMIC	11.915	Gain
CK1_CK1_CK1-D_CSNK1D_ST	P46937	YAP1	P48730	CSNK1D	S164	I167T	167	Missense	distal	3	no	10.651	12.072	EPSD	COSMIC	11.915	Gain
CK1_CK1_CK1-D_CSNK1D_ST	P46937	YAP1	P48730	CSNK1D	S217	V212I	212	Missense	distal	-5	no	12.270	10.207	EPSD	COSMIC	11.915	Loss
CK1_CK1_CK1-D_CSNK1D_ST	P46937	YAP1	P48730	CSNK1D	S217	M210I	210	Missense	distal	-7	no	12.270	12.161	EPSD	COSMIC	11.915	Down-regulation
CK1_CK1_CK1-D_CSNK1D_ST	P46937	YAP1	P48730	CSNK1D	S274	V279L	279	Missense	distal	5	no	12.283	11.929	EPSD	COSMIC	11.915	Down-regulation
CK1_CK1_CK1-D_CSNK1D_ST	P46937	YAP1	P48730	CSNK1D	S274	S274G	274	Missense	central	0	yes	12.283	0.000	EPSD	COSMIC	11.915	Loss
CK1_CK1_CK1-D_CSNK1D_ST	P46937	YAP1	P48730	CSNK1D	S274	P278S	278	Missense	distal	4	no	12.283	11.978	EPSD	COSMIC	11.915	Down-regulation
CK1_CK1_CK1-D_CSNK1D_ST	P46937	YAP1	P48730	CSNK1D	S274	S276R	276	Missense	proximal	2	no	12.283	12.050	EPSD	COSMIC	11.915	Down-regulation
CK1_CK1_CK1-D_CSNK1D_ST	P46937	YAP1	P48730	CSNK1D	S274	A268V	268	Missense	distal	-6	no	12.283	11.971	EPSD	COSMIC	11.915	Down-regulation
CK1_CK1_CK1-D_CSNK1D_ST	P46937	YAP1	P48730	CSNK1D	S274	Q281H	281	Missense	distal	7	no	12.283	13.966	EPSD	COSMIC	11.915	Up-regulation
CK1_CK1_CK1-D_CSNK1D_ST	P46937	YAP1	P48730	CSNK1D	S300	S300N	300	Missense	central	0	yes	15.258	0.000	EPSD	COSMIC	11.915	Loss
CK1_CK1_CK1-D_CSNK1D_ST	P46937	YAP1	P48730	CSNK1D	S300	N299S	299	Missense	proximal	-1	no	15.258	14.923	EPSD	COSMIC	11.915	Down-regulation
CK1_CK1_CK1-D_CSNK1D_ST	P46937	YAP1	P48730	CSNK1D	S300	M306I	306	Missense	distal	6	no	15.258	11.657	EPSD	COSMIC	11.915	Loss
CK1_CK1_CK1-D_CSNK1D_ST	P46937	YAP1	P48730	CSNK1D	S400	D399G	399	Missense	proximal	-1	no	16.819	16.422	EPSD	COSMIC	11.915	Down-regulation
CK1_CK1_CK1-D_CSNK1D_ST	P46937	YAP1	P48730	CSNK1D	S400	E396K	396	Missense	distal	-4	no	16.819	16.670	EPSD	COSMIC	11.915	Down-regulation
CK1_CK1_CK1-D_CSNK1D_ST	P46937	YAP1	P48730	CSNK1D	S400	D399H	399	Missense	proximal	-1	no	16.819	15.084	EPSD	COSMIC	11.915	Down-regulation
CK1_CK1_CK1-D_CSNK1D_ST	P46937	YAP1	P48730	CSNK1D	S400	D395G	395	Missense	distal	-5	no	16.819	17.025	EPSD	COSMIC	11.915	Up-regulation
CK1_CK1_CK1-D_CSNK1D_ST	Q96T88	UHRF1	P48730	CSNK1D	S95	L90V	90	Missense	distal	-5	no	10.306	12.866	PhosphoSitePlus	COSMIC	11.915	Gain
CK1_CK1_CK1-D_CSNK1D_ST	Q96T88	UHRF1	P48730	CSNK1D	S102	G100R	100	Missense	proximal	-2	no	12.310	10.992	EPSD	COSMIC	11.915	Loss
CK1_CK1_CK1-D_CSNK1D_ST	Q96T88	UHRF1	P48730	CSNK1D	S102	D105Y	105	Missense	distal	3	no	12.310	9.281	EPSD	COSMIC	11.915	Loss
CK1_CK1_CK1-D_CSNK1D_ST	Q96T88	UHRF1	P48730	CSNK1D	S102	D105N	105	Missense	distal	3	no	12.310	12.752	EPSD	COSMIC	11.915	Up-regulation
CK1_CK1_CK1-D_CSNK1D_ST	Q96T88	UHRF1	P48730	CSNK1D	S102	E103K	103	Missense	proximal	1	no	12.310	8.929	EPSD	COSMIC	11.915	Loss
CK1_CK1_CK1-D_CSNK1D_ST	Q96T88	UHRF1	P48730	CSNK1D	S102	L99P	99	Missense	distal	-3	no	12.310	10.515	EPSD	COSMIC	11.915	Loss
CK1_CK1_CK1-D_CSNK1D_ST	Q96T88	UHRF1	P48730	CSNK1D	S104	G100R	100	Missense	distal	-4	no	13.576	13.359	EPSD	COSMIC	11.915	Down-regulation
CK1_CK1_CK1-D_CSNK1D_ST	Q96T88	UHRF1	P48730	CSNK1D	S104	G111S	111	Missense	distal	7	no	13.576	12.709	EPSD	COSMIC	11.915	Down-regulation
CK1_CK1_CK1-D_CSNK1D_ST	Q96T88	UHRF1	P48730	CSNK1D	S104	G111D	111	Missense	distal	7	no	13.576	13.779	EPSD	COSMIC	11.915	Up-regulation
CK1_CK1_CK1-D_CSNK1D_ST	Q96T88	UHRF1	P48730	CSNK1D	S104	D105Y	105	Missense	proximal	1	no	13.576	11.056	EPSD	COSMIC	11.915	Loss
CK1_CK1_CK1-D_CSNK1D_ST	Q96T88	UHRF1	P48730	CSNK1D	S104	D105N	105	Missense	proximal	1	no	13.576	12.268	EPSD	COSMIC	11.915	Down-regulation
CK1_CK1_CK1-D_CSNK1D_ST	Q96T88	UHRF1	P48730	CSNK1D	S104	E103K	103	Missense	proximal	-1	no	13.576	12.790	EPSD	COSMIC	11.915	Down-regulation
CK1_CK1_CK1-D_CSNK1D_ST	Q96T88	UHRF1	P48730	CSNK1D	S104	L99P	99	Missense	distal	-5	no	13.576	15.209	EPSD	COSMIC	11.915	Up-regulation
CK1_CK1_CK1-D_CSNK1D_ST	Q96T88	UHRF1	P48730	CSNK1D	S108	A115T	115	Missense	distal	7	no	14.410	16.205	EPSD	COSMIC	11.915	Up-regulation
CK1_CK1_CK1-D_CSNK1D_ST	Q96T88	UHRF1	P48730	CSNK1D	S108	A115V	115	Missense	distal	7	no	14.410	15.332	EPSD	COSMIC	11.915	Up-regulation
CK1_CK1_CK1-D_CSNK1D_ST	Q96T88	UHRF1	P48730	CSNK1D	S108	G111S	111	Missense	distal	3	no	14.410	15.332	EPSD	COSMIC	11.915	Up-regulation
CK1_CK1_CK1-D_CSNK1D_ST	Q96T88	UHRF1	P48730	CSNK1D	S108	G111D	111	Missense	distal	3	no	14.410	14.532	EPSD	COSMIC	11.915	Up-regulation
CK1_CK1_CK1-D_CSNK1D_ST	Q96T88	UHRF1	P48730	CSNK1D	S108	A114S	114	Missense	distal	6	no	14.410	16.050	EPSD	COSMIC	11.915	Up-regulation
CK1_CK1_CK1-D_CSNK1D_ST	Q96T88	UHRF1	P48730	CSNK1D	S108	D105Y	105	Missense	distal	-3	no	14.410	12.905	EPSD	COSMIC	11.915	Down-regulation
CK1_CK1_CK1-D_CSNK1D_ST	Q96T88	UHRF1	P48730	CSNK1D	S108	D105N	105	Missense	distal	-3	no	14.410	11.967	EPSD	COSMIC	11.915	Down-regulation
CK1_CK1_CK1-D_CSNK1D_ST	Q96T88	UHRF1	P48730	CSNK1D	S108	E103K	103	Missense	distal	-5	no	14.410	12.832	EPSD	COSMIC	11.915	Down-regulation
CK1_CK1_CK1-D_CSNK1D_ST	Q96T88	UHRF1	P48730	CSNK1D	S119	E116K	116	Missense	distal	-3	no	15.584	12.938	EPSD	COSMIC	11.915	Down-regulation
CK1_CK1_CK1-D_CSNK1D_ST	Q96T88	UHRF1	P48730	CSNK1D	S119	A115T	115	Missense	distal	-4	no	15.584	14.887	EPSD	COSMIC	11.915	Down-regulation
CK1_CK1_CK1-D_CSNK1D_ST	Q96T88	UHRF1	P48730	CSNK1D	S119	D125Y	125	Missense	distal	6	no	15.584	13.632	EPSD	COSMIC	11.915	Down-regulation
CK1_CK1_CK1-D_CSNK1D_ST	Q96T88	UHRF1	P48730	CSNK1D	S119	A115V	115	Missense	distal	-4	no	15.584	14.817	EPSD	COSMIC	11.915	Down-regulation
CK1_CK1_CK1-D_CSNK1D_ST	Q96T88	UHRF1	P48730	CSNK1D	S119	D123N	123	Missense	distal	4	no	15.584	14.883	EPSD	COSMIC	11.915	Down-regulation
CK1_CK1_CK1-D_CSNK1D_ST	Q96T88	UHRF1	P48730	CSNK1D	S119	S119N	119	Missense	central	0	yes	15.584	0.000	EPSD	COSMIC	11.915	Loss
CK1_CK1_CK1-D_CSNK1D_ST	Q96T88	UHRF1	P48730	CSNK1D	S119	A114S	114	Missense	distal	-5	no	15.584	15.158	EPSD	COSMIC	11.915	Down-regulation
CK1_CK1_CK1-D_CSNK1D_ST	Q96T88	UHRF1	P48730	CSNK1D	T130	L132V	132	Missense	proximal	2	no	11.606	12.698	EPSD	COSMIC	11.915	Gain
CK1_CK1_CK1-D_CSNK1D_ST	Q96T88	UHRF1	P48730	CSNK1D	T130	D123N	123	Missense	distal	-7	no	11.606	12.470	EPSD	COSMIC	11.915	Gain
CK1_CK1_CK1-D_CSNK1D_ST	Q96T88	UHRF1	P48730	CSNK1D	T130	K136N	136	Missense	distal	6	no	11.606	12.800	EPSD	COSMIC	11.915	Gain
CK1_CK1_CK1-D_CSNK1D_ST	Q96T88	UHRF1	P48730	CSNK1D	S174	S172C	172	Missense	proximal	-2	no	11.571	12.547	EPSD	COSMIC	11.915	Gain
CK1_CK1_CK1-D_CSNK1D_ST	Q96T88	UHRF1	P48730	CSNK1D	S265	D264Y	264	Missense	proximal	-1	no	13.830	12.300	EPSD	COSMIC	11.915	Down-regulation
CK1_CK1_CK1-D_CSNK1D_ST	Q96T88	UHRF1	P48730	CSNK1D	S265	S265Y	265	Missense	central	0	yes	13.830	0.000	EPSD	COSMIC	11.915	Loss
CK1_CK1_CK1-D_CSNK1D_ST	Q96T88	UHRF1	P48730	CSNK1D	S393	S393A	393	Missense	central	0	yes	13.496	0.000	EPSD	COSMIC	11.915	Loss
CK1_CK1_CK1-D_CSNK1D_ST	Q96T88	UHRF1	P48730	CSNK1D	S393	S391L	391	Missense	proximal	-2	no	13.496	9.876	EPSD	COSMIC	11.915	Loss
CK1_CK1_CK1-D_CSNK1D_ST	Q96T88	UHRF1	P48730	CSNK1D	T411	P414S	414	Missense	distal	3	no	11.646	14.414	EPSD	COSMIC	11.915	Gain
CK1_CK1_CK1-D_CSNK1D_ST	Q96T88	UHRF1	P48730	CSNK1D	S439	E438K	438	Missense	proximal	-1	no	11.946	11.160	EPSD	COSMIC	11.915	Loss
CK1_CK1_CK1-D_CSNK1D_ST	Q96T88	UHRF1	P48730	CSNK1D	S639	G636S	636	Missense	distal	-3	no	13.071	13.820	EPSD	COSMIC	11.915	Up-regulation
CK1_CK1_CK1-D_CSNK1D_ST	Q96T88	UHRF1	P48730	CSNK1D	S639	G645C	645	Missense	distal	6	no	13.071	9.556	EPSD	COSMIC	11.915	Loss
CK1_CK1_CK1-D_CSNK1D_ST	Q96T88	UHRF1	P48730	CSNK1D	S639	G636V	636	Missense	distal	-3	no	13.071	10.478	EPSD	COSMIC	11.915	Loss
CK1_CK1_CK1-D_CSNK1D_ST	Q96T88	UHRF1	P48730	CSNK1D	S639	Q632E	632	Missense	distal	-7	no	13.071	14.529	EPSD	COSMIC	11.915	Up-regulation
CK1_CK1_CK1-D_CSNK1D_ST	Q96T88	UHRF1	P48730	CSNK1D	S639	P640T	640	Missense	proximal	1	no	13.071	11.897	EPSD	COSMIC	11.915	Loss
CK1_CK1_CK1-D_CSNK1D_ST	Q96T88	UHRF1	P48730	CSNK1D	S639	E634K	634	Missense	distal	-5	no	13.071	11.494	EPSD	COSMIC	11.915	Loss
CK1_CK1_CK1-D_CSNK1D_ST	Q96T88	UHRF1	P48730	CSNK1D	S639	R641H	641	Missense	proximal	2	no	13.071	12.223	EPSD	COSMIC	11.915	Down-regulation
CK1_CK1_CK1-D_CSNK1D_ST	Q96T88	UHRF1	P48730	CSNK1D	S639	G636E	636	Missense	distal	-3	no	13.071	13.172	EPSD	COSMIC	11.915	Up-regulation
CK1_CK1_CK1-D_CSNK1D_ST	Q96T88	UHRF1	P48730	CSNK1D	S639	F637L	637	Missense	proximal	-2	no	13.071	11.192	EPSD	COSMIC	11.915	Loss
CK1_CK1_CK1-D_CSNK1D_ST	O43312	MTSS1	P48730	CSNK1D	S142	Q135E	135	Missense	distal	-7	no	10.573	12.031	EPSD	COSMIC	11.915	Gain
CK1_CK1_CK1-D_CSNK1D_ST	O43312	MTSS1	P48730	CSNK1D	S290	G289A	289	Missense	proximal	-1	no	11.802	12.673	EPSD	COSMIC	11.915	Gain
CK1_CK1_CK1-D_CSNK1D_ST	O43312	MTSS1	P48730	CSNK1D	S316	V312A	312	Missense	distal	-4	no	11.192	11.959	EPSD	COSMIC	11.915	Gain
CK1_CK1_CK1-D_CSNK1D_ST	O43312	MTSS1	P48730	CSNK1D	S322	A329T	329	Missense	distal	7	no	12.960	14.755	PhosphoSitePlus	COSMIC	11.915	Up-regulation
CK1_CK1_CK1-D_CSNK1D_ST	O43312	MTSS1	P48730	CSNK1D	S446	G439R	439	Missense	distal	-7	no	14.585	12.772	EPSD	COSMIC	11.915	Down-regulation
CK1_CK1_CK1-D_CSNK1D_ST	O43312	MTSS1	P48730	CSNK1D	S446	G441R	441	Missense	distal	-5	no	14.585	14.258	EPSD	COSMIC	11.915	Down-regulation
CK1_CK1_CK1-D_CSNK1D_ST	O43312	MTSS1	P48730	CSNK1D	S446	G447C	447	Missense	proximal	1	no	14.585	12.089	EPSD	COSMIC	11.915	Down-regulation
CK1_CK1_CK1-D_CSNK1D_ST	O43312	MTSS1	P48730	CSNK1D	S446	G447S	447	Missense	proximal	1	no	14.585	11.425	EPSD	COSMIC	11.915	Loss
CK1_CK1_CK1-D_CSNK1D_ST	O43312	MTSS1	P48730	CSNK1D	S446	G439E	439	Missense	distal	-7	no	14.585	14.909	EPSD	COSMIC	11.915	Up-regulation
CK1_CK1_CK1-D_CSNK1D_ST	O43312	MTSS1	P48730	CSNK1D	S484	L481M	481	Missense	distal	-3	no	12.393	12.661	EPSD	COSMIC	11.915	Up-regulation
CK1_CK1_CK1-D_CSNK1D_ST	O43312	MTSS1	P48730	CSNK1D	S555	S555N	555	Missense	central	0	yes	12.852	0.000	EPSD	COSMIC	11.915	Loss
CK1_CK1_CK1-D_CSNK1D_ST	O43312	MTSS1	P48730	CSNK1D	T658	G651C	651	Missense	distal	-7	no	14.453	12.754	EPSD	COSMIC	11.915	Down-regulation
CK1_CK1_CK1-D_CSNK1D_ST	O43312	MTSS1	P48730	CSNK1D	T658	S659R	659	Missense	proximal	1	no	14.453	15.793	EPSD	COSMIC	11.915	Up-regulation
CK1_CK1_CK1-D_CSNK1D_ST	O43312	MTSS1	P48730	CSNK1D	T658	M664I	664	Missense	distal	6	no	14.453	10.852	EPSD	COSMIC	11.915	Loss
CK1_CK1_CK1-D_CSNK1D_ST	O43312	MTSS1	P48730	CSNK1D	T658	E652D	652	Missense	distal	-6	no	14.453	13.765	EPSD	COSMIC	11.915	Down-regulation
CK1_CK1_CK1-D_CSNK1D_ST	O43312	MTSS1	P48730	CSNK1D	T658	S663R	663	Missense	distal	5	no	14.453	14.121	EPSD	COSMIC	11.915	Down-regulation
CK1_CK1_CK1-D_CSNK1D_ST	O43312	MTSS1	P48730	CSNK1D	S666	S659R	659	Missense	distal	-7	no	13.216	12.058	EPSD	COSMIC	11.915	Down-regulation
CK1_CK1_CK1-D_CSNK1D_ST	O43312	MTSS1	P48730	CSNK1D	S666	V671I	671	Missense	distal	5	no	13.216	13.501	EPSD	COSMIC	11.915	Up-regulation
CK1_CK1_CK1-D_CSNK1D_ST	O43312	MTSS1	P48730	CSNK1D	S666	M664I	664	Missense	proximal	-2	no	13.216	10.818	EPSD	COSMIC	11.915	Loss
CK1_CK1_CK1-D_CSNK1D_ST	O43312	MTSS1	P48730	CSNK1D	S666	S663R	663	Missense	distal	-3	no	13.216	12.028	EPSD	COSMIC	11.915	Down-regulation
CK1_CK1_CK1-D_CSNK1D_ST	O43312	MTSS1	P48730	CSNK1D	S666	S670R	670	Missense	distal	4	no	13.216	13.462	EPSD	COSMIC	11.915	Up-regulation
CK1_CK1_CK1-D_CSNK1D_ST	Q9BZL6	PRKD2	P48730	CSNK1D	S189	R195S	195	Missense	distal	6	no	9.096	12.007	EPSD	COSMIC	11.915	Gain
CK1_CK1_CK1-D_CSNK1D_ST	Q9BZL6	PRKD2	P48730	CSNK1D	S200	S203I	203	Missense	distal	3	no	14.712	11.755	EPSD	COSMIC	11.915	Loss
CK1_CK1_CK1-D_CSNK1D_ST	Q9BZL6	PRKD2	P48730	CSNK1D	S200	R195S	195	Missense	distal	-5	no	14.712	14.824	EPSD	COSMIC	11.915	Up-regulation
CK1_CK1_CK1-D_CSNK1D_ST	Q9BZL6	PRKD2	P48730	CSNK1D	S200	A202V	202	Missense	proximal	2	no	14.712	13.553	EPSD	COSMIC	11.915	Down-regulation
CK1_CK1_CK1-D_CSNK1D_ST	Q9BZL6	PRKD2	P48730	CSNK1D	S200	S203C	203	Missense	distal	3	no	14.712	11.700	EPSD	COSMIC	11.915	Loss
CK1_CK1_CK1-D_CSNK1D_ST	Q9BZL6	PRKD2	P48730	CSNK1D	S223	E220K	220	Missense	distal	-3	no	14.388	11.741	EPSD	COSMIC	11.915	Loss
CK1_CK1_CK1-D_CSNK1D_ST	Q9BZL6	PRKD2	P48730	CSNK1D	S225	R232H	232	Missense	distal	7	no	9.510	12.464	EPSD	COSMIC	11.915	Gain
CK1_CK1_CK1-D_CSNK1D_ST	Q9BZL6	PRKD2	P48730	CSNK1D	S245	R249S	249	Missense	distal	4	no	12.858	12.613	EPSD	COSMIC	11.915	Down-regulation
CK1_CK1_CK1-D_CSNK1D_ST	Q9BZL6	PRKD2	P48730	CSNK1D	S245	S239F	239	Missense	distal	-6	no	12.858	12.130	EPSD	COSMIC	11.915	Down-regulation
CK1_CK1_CK1-D_CSNK1D_ST	Q9BZL6	PRKD2	P48730	CSNK1D	S245	S241Y	241	Missense	distal	-4	no	12.858	12.022	EPSD	COSMIC	11.915	Down-regulation
CK1_CK1_CK1-D_CSNK1D_ST	Q9BZL6	PRKD2	P48730	CSNK1D	T247	R249S	249	Missense	proximal	2	no	11.776	12.009	EPSD	COSMIC	11.915	Gain
CK1_CK1_CK1-D_CSNK1D_ST	Q9BZL6	PRKD2	P48730	CSNK1D	S344	S347C	347	Missense	distal	3	no	13.396	10.384	EPSD	COSMIC	11.915	Loss
CK1_CK1_CK1-D_CSNK1D_ST	Q9BZL6	PRKD2	P48730	CSNK1D	S362	A361T	361	Missense	proximal	-1	no	16.185	14.831	EPSD	COSMIC	11.915	Down-regulation
CK1_CK1_CK1-D_CSNK1D_ST	Q9BZL6	PRKD2	P48730	CSNK1D	S362	G367V	367	Missense	distal	5	no	16.185	15.353	EPSD	COSMIC	11.915	Down-regulation
CK1_CK1_CK1-D_CSNK1D_ST	Q9BZL6	PRKD2	P48730	CSNK1D	S375	S374G	374	Missense	proximal	-1	no	13.244	13.183	EPSD	COSMIC	11.915	Down-regulation
CK1_CK1_CK1-D_CSNK1D_ST	Q9BZL6	PRKD2	P48730	CSNK1D	S375	L376V	376	Missense	proximal	1	no	13.244	14.238	EPSD	COSMIC	11.915	Up-regulation
CK1_CK1_CK1-D_CSNK1D_ST	P43629	KIR3DL1	P48730	CSNK1D	S246	S249F	249	Missense	distal	3	no	15.252	14.092	EPSD	COSMIC;GDSC;CCLE	11.915	Down-regulation
CK1_CK1_CK1-D_CSNK1D_ST	P43629	KIR3DL1	P48730	CSNK1D	S385	D389V	389	Missense	distal	4	no	15.402	16.088	EPSD;PhosphoSitePlus	COSMIC	11.915	Up-regulation
CK1_CK1_CK1-D_CSNK1D_ST	P43629	KIR3DL1	P48730	CSNK1D	S385	D392G	392	Missense	distal	7	no	15.402	15.199	EPSD;PhosphoSitePlus	COSMIC	11.915	Down-regulation
CK1_CK1_CK1-D_CSNK1D_ST	P43629	KIR3DL1	P48730	CSNK1D	S385	E386K	386	Missense	proximal	1	no	15.402	12.021	EPSD;PhosphoSitePlus	COSMIC	11.915	Down-regulation
CK1_CK1_CK1-D_CSNK1D_ST	P43629	KIR3DL1	P48730	CSNK1D	S388	E394Q	394	Missense	distal	6	no	19.910	18.156	PhosphoSitePlus;EPSD	COSMIC	11.915	Down-regulation
CK1_CK1_CK1-D_CSNK1D_ST	P43629	KIR3DL1	P48730	CSNK1D	S388	D389V	389	Missense	proximal	1	no	19.910	20.547	PhosphoSitePlus;EPSD	COSMIC	11.915	Up-regulation
CK1_CK1_CK1-D_CSNK1D_ST	P43629	KIR3DL1	P48730	CSNK1D	S388	D392G	392	Missense	distal	4	no	19.910	19.637	PhosphoSitePlus;EPSD	COSMIC	11.915	Down-regulation
CK1_CK1_CK1-D_CSNK1D_ST	P43629	KIR3DL1	P48730	CSNK1D	S388	E386K	386	Missense	proximal	-2	no	19.910	18.634	PhosphoSitePlus;EPSD	COSMIC	11.915	Down-regulation
CK1_CK1_CK1-D_CSNK1D_ST	Q9Y6Q9	NCOA3	P48730	CSNK1D	S32	R38W	38	Missense	distal	6	no	10.493	12.521	EPSD	COSMIC	11.915	Gain
CK1_CK1_CK1-D_CSNK1D_ST	Q9Y6Q9	NCOA3	P48730	CSNK1D	S284	V277A	277	Missense	distal	-7	no	10.826	12.903	EPSD	COSMIC	11.915	Gain
CK1_CK1_CK1-D_CSNK1D_ST	Q9Y6Q9	NCOA3	P48730	CSNK1D	S551	K547T	547	Missense	distal	-4	no	13.774	13.629	EPSD	COSMIC	11.915	Down-regulation
CK1_CK1_CK1-D_CSNK1D_ST	Q9Y6Q9	NCOA3	P48730	CSNK1D	S551	D549N	549	Missense	proximal	-2	no	13.774	11.441	EPSD	COSMIC	11.915	Loss
CK1_CK1_CK1-D_CSNK1D_ST	Q9Y6Q9	NCOA3	P48730	CSNK1D	S583	P579S	579	Missense	distal	-4	no	12.872	13.337	EPSD	COSMIC	11.915	Up-regulation
CK1_CK1_CK1-D_CSNK1D_ST	Q9Y6Q9	NCOA3	P48730	CSNK1D	S583	S587L	587	Missense	distal	4	no	12.872	13.236	EPSD	COSMIC	11.915	Up-regulation
CK1_CK1_CK1-D_CSNK1D_ST	Q9Y6Q9	NCOA3	P48730	CSNK1D	S583	M584L	584	Missense	proximal	1	no	12.872	14.195	EPSD	COSMIC	11.915	Up-regulation
CK1_CK1_CK1-D_CSNK1D_ST	Q9Y6Q9	NCOA3	P48730	CSNK1D	S583	R590T	590	Missense	distal	7	no	12.872	14.601	EPSD	COSMIC	11.915	Up-regulation
CK1_CK1_CK1-D_CSNK1D_ST	Q9Y6Q9	NCOA3	P48730	CSNK1D	S583	R590K	590	Missense	distal	7	no	12.872	13.271	EPSD	COSMIC	11.915	Up-regulation
CK1_CK1_CK1-D_CSNK1D_ST	Q9Y6Q9	NCOA3	P48730	CSNK1D	S583	D576N	576	Missense	distal	-7	no	12.872	13.736	EPSD	COSMIC	11.915	Up-regulation
CK1_CK1_CK1-D_CSNK1D_ST	Q9Y6Q9	NCOA3	P48730	CSNK1D	S589	S594G	594	Missense	distal	5	no	13.105	13.033	EPSD	COSMIC	11.915	Down-regulation
CK1_CK1_CK1-D_CSNK1D_ST	Q9Y6Q9	NCOA3	P48730	CSNK1D	S589	S587L	587	Missense	proximal	-2	no	13.105	9.485	EPSD	COSMIC	11.915	Loss
CK1_CK1_CK1-D_CSNK1D_ST	Q9Y6Q9	NCOA3	P48730	CSNK1D	S589	M584L	584	Missense	distal	-5	no	13.105	12.099	EPSD	COSMIC	11.915	Down-regulation
CK1_CK1_CK1-D_CSNK1D_ST	Q9Y6Q9	NCOA3	P48730	CSNK1D	S589	R590T	590	Missense	proximal	1	no	13.105	12.910	EPSD	COSMIC	11.915	Down-regulation
CK1_CK1_CK1-D_CSNK1D_ST	Q9Y6Q9	NCOA3	P48730	CSNK1D	S589	R590K	590	Missense	proximal	1	no	13.105	10.930	EPSD	COSMIC	11.915	Loss
CK1_CK1_CK1-D_CSNK1D_ST	Q9Y6Q9	NCOA3	P48730	CSNK1D	S589	L593H	593	Missense	distal	4	no	13.105	13.505	EPSD	COSMIC	11.915	Up-regulation
CK1_CK1_CK1-D_CSNK1D_ST	Q9Y6Q9	NCOA3	P48730	CSNK1D	S598	G605W	605	Missense	distal	7	no	10.428	12.896	EPSD	COSMIC	11.915	Gain
CK1_CK1_CK1-D_CSNK1D_ST	Q9Y6Q9	NCOA3	P48730	CSNK1D	S601	S594G	594	Missense	distal	-7	no	19.748	20.403	PhosphoSitePlus	COSMIC	11.915	Up-regulation
CK1_CK1_CK1-D_CSNK1D_ST	Q9Y6Q9	NCOA3	P48730	CSNK1D	S601	S601N	601	Missense	central	0	yes	19.748	0.000	PhosphoSitePlus	COSMIC	11.915	Loss
CK1_CK1_CK1-D_CSNK1D_ST	Q9Y6Q9	NCOA3	P48730	CSNK1D	S601	S598R	598	Missense	distal	-3	no	19.748	18.560	PhosphoSitePlus	COSMIC	11.915	Down-regulation
CK1_CK1_CK1-D_CSNK1D_ST	Q9Y6Q9	NCOA3	P48730	CSNK1D	S601	G605W	605	Missense	distal	4	no	19.748	20.331	PhosphoSitePlus	COSMIC	11.915	Up-regulation
CK1_CK1_CK1-D_CSNK1D_ST	Q9Y6Q9	NCOA3	P48730	CSNK1D	S602	S601N	601	Missense	proximal	-1	no	13.759	14.093	EPSD	COSMIC	11.915	Up-regulation
CK1_CK1_CK1-D_CSNK1D_ST	Q9Y6Q9	NCOA3	P48730	CSNK1D	S602	S598R	598	Missense	distal	-4	no	13.759	13.251	EPSD	COSMIC	11.915	Down-regulation
CK1_CK1_CK1-D_CSNK1D_ST	Q9Y6Q9	NCOA3	P48730	CSNK1D	S602	G605W	605	Missense	distal	3	no	13.759	13.476	EPSD	COSMIC	11.915	Down-regulation
CK1_CK1_CK1-D_CSNK1D_ST	Q9Y6Q9	NCOA3	P48730	CSNK1D	S652	E648K	648	Missense	distal	-4	no	15.054	14.904	EPSD	COSMIC	11.915	Down-regulation
CK1_CK1_CK1-D_CSNK1D_ST	Q9Y6Q9	NCOA3	P48730	CSNK1D	S655	E648K	648	Missense	distal	-7	no	13.926	11.994	EPSD	COSMIC	11.915	Down-regulation
CK1_CK1_CK1-D_CSNK1D_ST	Q9Y6Q9	NCOA3	P48730	CSNK1D	S767	N764Y	764	Missense	distal	-3	no	12.982	13.920	EPSD	COSMIC	11.915	Up-regulation
CK1_CK1_CK1-D_CSNK1D_ST	Q9Y6Q9	NCOA3	P48730	CSNK1D	S857	S863F	863	Missense	distal	6	no	13.588	13.040	EPSD	COSMIC	11.915	Down-regulation
CK1_CK1_CK1-D_CSNK1D_ST	Q9Y6Q9	NCOA3	P48730	CSNK1D	S857	P850S	850	Missense	distal	-7	no	13.588	13.103	EPSD	COSMIC	11.915	Down-regulation
CK1_CK1_CK1-D_CSNK1D_ST	Q9Y6Q9	NCOA3	P48730	CSNK1D	S857	S857C	857	Missense	central	0	yes	13.588	0.000	EPSD	COSMIC	11.915	Loss
CK1_CK1_CK1-D_CSNK1D_ST	Q9Y6Q9	NCOA3	P48730	CSNK1D	S1329	S1330G	1330	Missense	proximal	1	no	9.097	12.256	EPSD	COSMIC	11.915	Gain
CK1_CK1_CK1-D_CSNK1D_ST	P30291	WEE1	P48730	CSNK1D	S45	G50S	50	Missense	distal	5	no	16.502	16.574	EPSD	COSMIC	11.915	Up-regulation
CK1_CK1_CK1-D_CSNK1D_ST	P30291	WEE1	P48730	CSNK1D	S45	D52G	52	Missense	distal	7	no	16.502	16.299	EPSD	COSMIC	11.915	Down-regulation
CK1_CK1_CK1-D_CSNK1D_ST	P30291	WEE1	P48730	CSNK1D	S48	G50S	50	Missense	proximal	2	no	15.450	15.080	EPSD	COSMIC	11.915	Down-regulation
CK1_CK1_CK1-D_CSNK1D_ST	P30291	WEE1	P48730	CSNK1D	S48	D52G	52	Missense	distal	4	no	15.450	15.177	EPSD	COSMIC	11.915	Down-regulation
CK1_CK1_CK1-D_CSNK1D_ST	P30291	WEE1	P48730	CSNK1D	T49	G50S	50	Missense	proximal	1	no	12.931	9.771	EPSD	COSMIC	11.915	Loss
CK1_CK1_CK1-D_CSNK1D_ST	P30291	WEE1	P48730	CSNK1D	T49	D52G	52	Missense	distal	3	no	12.931	12.808	EPSD	COSMIC	11.915	Down-regulation
CK1_CK1_CK1-D_CSNK1D_ST	P30291	WEE1	P48730	CSNK1D	T49	Q56E	56	Missense	distal	7	no	12.931	11.817	EPSD	COSMIC	11.915	Loss
CK1_CK1_CK1-D_CSNK1D_ST	P30291	WEE1	P48730	CSNK1D	S123	A129T	129	Missense	distal	6	no	16.095	14.833	EPSD	COSMIC	11.915	Down-regulation
CK1_CK1_CK1-D_CSNK1D_ST	P30291	WEE1	P48730	CSNK1D	S242	L244F	244	Missense	proximal	2	no	13.310	14.154	EPSD	COSMIC	11.915	Up-regulation
CK1_CK1_CK1-D_CSNK1D_ST	P30291	WEE1	P48730	CSNK1D	T278	D271G	271	Missense	distal	-7	no	13.876	14.658	EPSD	COSMIC	11.915	Up-regulation
CK1_CK1_CK1-D_CSNK1D_ST	P30291	WEE1	P48730	CSNK1D	S559	P558S	558	Missense	proximal	-1	no	13.064	13.243	EPSD	COSMIC	11.915	Up-regulation
CK1_CK1_CK1-D_CSNK1D_ST	P30291	WEE1	P48730	CSNK1D	S559	R556I	556	Missense	distal	-3	no	13.064	6.180	EPSD	COSMIC	11.915	Loss
CK1_CK1_CK1-D_CSNK1D_ST	P30291	WEE1	P48730	CSNK1D	S592	K588Q	588	Missense	distal	-4	no	12.215	12.263	EPSD	COSMIC	11.915	Up-regulation
CK1_CK1_CK1-D_CSNK1D_ST	Q16665	HIF1A	P48730	CSNK1D	S14	R18G	18	Missense	distal	4	no	12.497	12.375	EPSD	COSMIC	11.915	Down-regulation
CK1_CK1_CK1-D_CSNK1D_ST	Q16665	HIF1A	P48730	CSNK1D	S14	R18H	18	Missense	distal	4	no	12.497	13.016	EPSD	COSMIC	11.915	Up-regulation
CK1_CK1_CK1-D_CSNK1D_ST	Q16665	HIF1A	P48730	CSNK1D	S14	S15R	15	Missense	proximal	1	no	12.497	13.836	EPSD	COSMIC	11.915	Up-regulation
CK1_CK1_CK1-D_CSNK1D_ST	Q16665	HIF1A	P48730	CSNK1D	S14	R17H	17	Missense	distal	3	no	12.497	14.578	EPSD	COSMIC	11.915	Up-regulation
CK1_CK1_CK1-D_CSNK1D_ST	Q16665	HIF1A	P48730	CSNK1D	S14	S14R	14	Missense	central	0	yes	12.497	0.000	EPSD	COSMIC	11.915	Loss
CK1_CK1_CK1-D_CSNK1D_ST	Q16665	HIF1A	P48730	CSNK1D	S14	E20K	20	Missense	distal	6	no	12.497	10.698	EPSD	COSMIC	11.915	Loss
CK1_CK1_CK1-D_CSNK1D_ST	Q16665	HIF1A	P48730	CSNK1D	S31	R30W	30	Missense	proximal	-1	no	13.466	12.329	EPSD	COSMIC	11.915	Down-regulation
CK1_CK1_CK1-D_CSNK1D_ST	Q16665	HIF1A	P48730	CSNK1D	S31	D24Y	24	Missense	distal	-7	no	13.466	11.161	EPSD	COSMIC	11.915	Loss
CK1_CK1_CK1-D_CSNK1D_ST	Q16665	HIF1A	P48730	CSNK1D	S31	R30Q	30	Missense	proximal	-1	no	13.466	13.752	EPSD	COSMIC	11.915	Up-regulation
CK1_CK1_CK1-D_CSNK1D_ST	Q16665	HIF1A	P48730	CSNK1D	S31	R29W	29	Missense	proximal	-2	no	13.466	7.297	EPSD	COSMIC	11.915	Loss
CK1_CK1_CK1-D_CSNK1D_ST	Q16665	HIF1A	P48730	CSNK1D	S58	I64M	64	Missense	distal	6	no	8.800	12.401	EPSD	COSMIC	11.915	Gain
CK1_CK1_CK1-D_CSNK1D_ST	Q16665	HIF1A	P48730	CSNK1D	S247	R245Q	245	Missense	proximal	-2	no	14.795	16.278	PhosphoSitePlus	COSMIC	11.915	Up-regulation
CK1_CK1_CK1-D_CSNK1D_ST	Q16665	HIF1A	P48730	CSNK1D	S247	Y254N	254	Missense	distal	7	no	14.795	14.739	PhosphoSitePlus	COSMIC	11.915	Down-regulation
CK1_CK1_CK1-D_CSNK1D_ST	Q16665	HIF1A	P48730	CSNK1D	S247	F242V	242	Missense	distal	-5	no	14.795	16.380	PhosphoSitePlus	COSMIC	11.915	Up-regulation
CK1_CK1_CK1-D_CSNK1D_ST	Q16665	HIF1A	P48730	CSNK1D	S247	M250I	250	Missense	distal	3	no	14.795	12.349	PhosphoSitePlus	COSMIC	11.915	Down-regulation
CK1_CK1_CK1-D_CSNK1D_ST	Q16665	HIF1A	P48730	CSNK1D	S247	K251N	251	Missense	distal	4	no	14.795	14.249	PhosphoSitePlus	COSMIC	11.915	Down-regulation
CK1_CK1_CK1-D_CSNK1D_ST	Q16665	HIF1A	P48730	CSNK1D	T290	H292R	292	Missense	proximal	2	no	11.757	12.605	EPSD	COSMIC	11.915	Gain
CK1_CK1_CK1-D_CSNK1D_ST	Q16665	HIF1A	P48730	CSNK1D	T301	R306M	306	Missense	distal	5	no	12.958	13.177	EPSD	COSMIC	11.915	Up-regulation
CK1_CK1_CK1-D_CSNK1D_ST	Q16665	HIF1A	P48730	CSNK1D	S488	T490A	490	Missense	proximal	2	no	12.994	14.500	EPSD	COSMIC	11.915	Up-regulation
CK1_CK1_CK1-D_CSNK1D_ST	Q16665	HIF1A	P48730	CSNK1D	S488	Q495K	495	Missense	distal	7	no	12.994	12.122	EPSD	COSMIC	11.915	Down-regulation
CK1_CK1_CK1-D_CSNK1D_ST	Q16665	HIF1A	P48730	CSNK1D	S488	Q495R	495	Missense	distal	7	no	12.994	11.724	EPSD	COSMIC	11.915	Loss
CK1_CK1_CK1-D_CSNK1D_ST	Q16665	HIF1A	P48730	CSNK1D	S509	R507K	507	Missense	proximal	-2	no	11.816	12.338	EPSD	COSMIC	11.915	Gain
CK1_CK1_CK1-D_CSNK1D_ST	Q16665	HIF1A	P48730	CSNK1D	S509	P516H	516	Missense	distal	7	no	11.816	14.435	EPSD	COSMIC	11.915	Gain
CK1_CK1_CK1-D_CSNK1D_ST	Q16665	HIF1A	P48730	CSNK1D	S510	R507K	507	Missense	distal	-3	no	13.317	11.211	EPSD	COSMIC	11.915	Loss
CK1_CK1_CK1-D_CSNK1D_ST	Q16665	HIF1A	P48730	CSNK1D	S510	E512V	512	Missense	proximal	2	no	13.317	12.373	EPSD	COSMIC;GDSC	11.915	Down-regulation
CK1_CK1_CK1-D_CSNK1D_ST	Q16665	HIF1A	P48730	CSNK1D	S510	P516H	516	Missense	distal	6	no	13.317	13.956	EPSD	COSMIC	11.915	Up-regulation
CK1_CK1_CK1-D_CSNK1D_ST	Q16665	HIF1A	P48730	CSNK1D	S510	S517T	517	Missense	distal	7	no	13.317	15.572	EPSD	COSMIC	11.915	Up-regulation
CK1_CK1_CK1-D_CSNK1D_ST	Q16665	HIF1A	P48730	CSNK1D	S510	D503N	503	Missense	distal	-7	no	13.317	14.181	EPSD	COSMIC	11.915	Up-regulation
CK1_CK1_CK1-D_CSNK1D_ST	Q16665	HIF1A	P48730	CSNK1D	S515	E512V	512	Missense	distal	-3	no	13.604	10.910	EPSD	COSMIC;GDSC	11.915	Loss
CK1_CK1_CK1-D_CSNK1D_ST	Q16665	HIF1A	P48730	CSNK1D	S515	P516H	516	Missense	proximal	1	no	13.604	14.744	EPSD	COSMIC	11.915	Up-regulation
CK1_CK1_CK1-D_CSNK1D_ST	Q16665	HIF1A	P48730	CSNK1D	S515	S517T	517	Missense	proximal	2	no	13.604	12.831	EPSD	COSMIC	11.915	Down-regulation
CK1_CK1_CK1-D_CSNK1D_ST	Q16665	HIF1A	P48730	CSNK1D	S515	Y522H	522	Missense	distal	7	no	13.604	16.225	EPSD	COSMIC	11.915	Up-regulation
CK1_CK1_CK1-D_CSNK1D_ST	Q16665	HIF1A	P48730	CSNK1D	T555	E560D	560	Missense	distal	5	no	12.551	12.527	EPSD	COSMIC	11.915	Down-regulation
CK1_CK1_CK1-D_CSNK1D_ST	Q16665	HIF1A	P48730	CSNK1D	T555	Q553K	553	Missense	proximal	-2	no	12.551	11.589	EPSD	COSMIC	11.915	Loss
CK1_CK1_CK1-D_CSNK1D_ST	Q16665	HIF1A	P48730	CSNK1D	T555	Q553H	553	Missense	proximal	-2	no	12.551	13.216	EPSD	COSMIC	11.915	Up-regulation
CK1_CK1_CK1-D_CSNK1D_ST	Q16665	HIF1A	P48730	CSNK1D	S760	R754H	754	Missense	distal	-6	no	11.939	10.597	EPSD	COSMIC	11.915	Loss
CK1_CK1_CK1-D_CSNK1D_ST	Q16665	HIF1A	P48730	CSNK1D	S760	K753R	753	Missense	distal	-7	no	11.939	11.735	EPSD	COSMIC	11.915	Loss
CK1_CK1_CK1-D_CSNK1D_ST	Q16665	HIF1A	P48730	CSNK1D	S760	K753N	753	Missense	distal	-7	no	11.939	13.630	EPSD	COSMIC	11.915	Up-regulation
CK1_CK1_CK1-D_CSNK1D_ST	Q16665	HIF1A	P48730	CSNK1D	S760	R754C	754	Missense	distal	-6	no	11.939	11.909	EPSD	COSMIC	11.915	Loss
CK1_CK1_CK1-D_CSNK1D_ST	Q16665	HIF1A	P48730	CSNK1D	S760	R754S	754	Missense	distal	-6	no	11.939	12.169	EPSD	COSMIC	11.915	Up-regulation
CK1_CK1_CK1-D_CSNK1D_ST	Q16665	HIF1A	P48730	CSNK1D	S761	R754H	754	Missense	distal	-7	no	13.332	12.490	EPSD	COSMIC	11.915	Down-regulation
CK1_CK1_CK1-D_CSNK1D_ST	Q16665	HIF1A	P48730	CSNK1D	S761	R754C	754	Missense	distal	-7	no	13.332	13.445	EPSD	COSMIC	11.915	Up-regulation
CK1_CK1_CK1-D_CSNK1D_ST	Q16665	HIF1A	P48730	CSNK1D	S761	R754S	754	Missense	distal	-7	no	13.332	14.490	EPSD	COSMIC	11.915	Up-regulation
CK1_CK1_CK1-D_CSNK1D_ST	Q16665	HIF1A	P48730	CSNK1D	S809	I806V	806	Missense	distal	-3	no	7.282	12.011	EPSD	COSMIC	11.915	Gain
CAMK_MAPKAPK_MNK_MKNK1_ST	P06730	EIF4E	Q9BUB5-2	MKNK1	S209	R214G	214	Missense	distal	5	no	11.229	11.377	PhosphoSitePlus	COSMIC	8.316	Up-regulation
CAMK_MAPKAPK_MNK_MKNK1_ST	P06730	EIF4E	Q9BUB5-2	MKNK1	T210	R214G	214	Missense	distal	4	no	10.960	9.671	EPSD	COSMIC	8.316	Down-regulation
Atypical_PDHK_PDHK_PDK4_ST	P08559	PDHA1	Q16654	PDK4	S130	E133K	133	Missense	distal	3	no	2.452	2.475	EPSD	COSMIC	1.272	Up-regulation
Atypical_PDHK_PDHK_PDK4_ST	P08559	PDHA1	Q16654	PDK4	S130	R127W	127	Missense	distal	-3	no	2.452	2.449	EPSD	COSMIC	1.272	Down-regulation
Atypical_PDHK_PDHK_PDK4_ST	P08559	PDHA1	Q16654	PDK4	S130	R132Q	132	Missense	proximal	2	no	2.452	2.296	EPSD	COSMIC	1.272	Down-regulation
Atypical_PDHK_PDHK_PDK4_ST	P08559	PDHA1	Q16654	PDK4	S130	A136T	136	Missense	distal	6	no	2.452	2.496	EPSD	COSMIC	1.272	Up-regulation
Atypical_PDHK_PDHK_PDK4_ST	P08559	PDHA1	Q16654	PDK4	S130	L135I	135	Missense	distal	5	no	2.452	2.431	EPSD	COSMIC	1.272	Down-regulation
Atypical_PDHK_PDHK_PDK4_ST	P08559	PDHA1	Q16654	PDK4	T286	Y287H	287	Missense	proximal	1	no	2.570	2.292	EPSD	COSMIC	1.272	Down-regulation
Atypical_PDHK_PDHK_PDK4_ST	P08559	PDHA1	Q16654	PDK4	T286	I280N	280	Missense	distal	-6	no	2.570	2.406	EPSD	COSMIC	1.272	Down-regulation
Atypical_PDHK_PDHK_PDK4_ST	P08559	PDHA1	Q16654	PDK4	T286	M282L	282	Missense	distal	-4	no	2.570	2.401	EPSD	COSMIC	1.272	Down-regulation
Atypical_PDHK_PDHK_PDK4_ST	P08559	PDHA1	Q16654	PDK4	T286	R288C	288	Missense	proximal	2	no	2.570	2.411	EPSD	COSMIC	1.272	Down-regulation
Atypical_PDHK_PDHK_PDK4_ST	P08559	PDHA1	Q16654	PDK4	S293	Y287H	287	Missense	distal	-6	no	14.613	14.307	PhosphoSitePlus;EPSD	COSMIC	1.272	Down-regulation
Atypical_PDHK_PDHK_PDK4_ST	P08559	PDHA1	Q16654	PDK4	S293	R288C	288	Missense	distal	-5	no	14.613	14.169	PhosphoSitePlus;EPSD	COSMIC	1.272	Down-regulation
Atypical_PDHK_PDHK_PDK4_ST	P08559	PDHA1	Q16654	PDK4	S300	R302S	302	Missense	proximal	2	no	14.281	14.188	EPSD;PhosphoSitePlus	COSMIC	1.272	Down-regulation
Atypical_PDHK_PDHK_PDK4_ST	P08559	PDHA1	Q16654	PDK4	S300	R304Q	304	Missense	distal	4	no	14.281	13.890	EPSD;PhosphoSitePlus	COSMIC;GDSC;CCLE	1.272	Down-regulation
Atypical_PDHK_PDHK_PDK4_ST	P08559	PDHA1	Q16654	PDK4	S300	R302C	302	Missense	proximal	2	no	14.281	14.122	EPSD;PhosphoSitePlus	COSMIC	1.272	Down-regulation
Atypical_PDHK_PDHK_PDK4_ST	P08559	PDHA1	Q16654	PDK4	S300	R302L	302	Missense	proximal	2	no	14.281	14.133	EPSD;PhosphoSitePlus	COSMIC	1.272	Down-regulation
Atypical_PDHK_PDHK_PDK4_ST	P29803	PDHA2	Q16654	PDK4	S128	G126R	126	Missense	proximal	-2	no	2.424	0.326	EPSD	COSMIC	1.272	Loss
Atypical_PDHK_PDHK_PDK4_ST	P29803	PDHA2	Q16654	PDK4	S128	R130Q	130	Missense	proximal	2	no	2.424	2.268	EPSD	COSMIC	1.272	Down-regulation
Atypical_PDHK_PDHK_PDK4_ST	P29803	PDHA2	Q16654	PDK4	S128	R125W	125	Missense	distal	-3	no	2.424	2.421	EPSD	COSMIC	1.272	Down-regulation
Atypical_PDHK_PDHK_PDK4_ST	P29803	PDHA2	Q16654	PDK4	S128	V129L	129	Missense	proximal	1	no	2.424	2.398	EPSD	COSMIC;GDSC;CCLE	1.272	Down-regulation
Atypical_PDHK_PDHK_PDK4_ST	P29803	PDHA2	Q16654	PDK4	S128	L133I	133	Missense	distal	5	no	2.424	2.403	EPSD	COSMIC	1.272	Down-regulation
Atypical_PDHK_PDHK_PDK4_ST	P29803	PDHA2	Q16654	PDK4	T231	A236V	236	Missense	distal	5	no	1.976	1.855	EPSD	COSMIC	1.272	Down-regulation
Atypical_PDHK_PDHK_PDK4_ST	P29803	PDHA2	Q16654	PDK4	T284	R286H	286	Missense	proximal	2	no	2.392	2.228	EPSD	COSMIC	1.272	Down-regulation
Atypical_PDHK_PDHK_PDK4_ST	P29803	PDHA2	Q16654	PDK4	T284	M280T	280	Missense	distal	-4	no	2.392	2.254	EPSD	COSMIC	1.272	Down-regulation
Atypical_PDHK_PDHK_PDK4_ST	P29803	PDHA2	Q16654	PDK4	T284	T284I	284	Missense	central	0	yes	2.392	0.000	EPSD	COSMIC	1.272	Loss
Atypical_PDHK_PDHK_PDK4_ST	P29803	PDHA2	Q16654	PDK4	T284	L282R	282	Missense	proximal	-2	no	2.392	2.153	EPSD	COSMIC	1.272	Down-regulation
Atypical_PDHK_PDHK_PDK4_ST	P29803	PDHA2	Q16654	PDK4	T284	T284P	284	Missense	central	0	yes	2.392	0.000	EPSD	COSMIC	1.272	Loss
Atypical_PDHK_PDHK_PDK4_ST	P29803	PDHA2	Q16654	PDK4	T284	P277L	277	Missense	distal	-7	no	2.392	2.285	EPSD	COSMIC	1.272	Down-regulation
Atypical_PDHK_PDHK_PDK4_ST	P29803	PDHA2	Q16654	PDK4	S291	R286H	286	Missense	distal	-5	no	13.830	13.373	EPSD;PhosphoSitePlus	COSMIC	1.272	Down-regulation
Atypical_PDHK_PDHK_PDK4_ST	P29803	PDHA2	Q16654	PDK4	S291	T284I	284	Missense	distal	-7	no	13.830	13.601	EPSD;PhosphoSitePlus	COSMIC	1.272	Down-regulation
Atypical_PDHK_PDHK_PDK4_ST	P29803	PDHA2	Q16654	PDK4	S291	T284P	284	Missense	distal	-7	no	13.830	13.684	EPSD;PhosphoSitePlus	COSMIC	1.272	Down-regulation
Atypical_PDHK_PDHK_PDK4_ST	P29803	PDHA2	Q16654	PDK4	S291	D294Y	294	Missense	distal	3	no	13.830	13.595	EPSD;PhosphoSitePlus	COSMIC;GDSC;CCLE	1.272	Down-regulation
Atypical_PDHK_PDHK_PDK4_ST	P29803	PDHA2	Q16654	PDK4	S298	E304K	304	Missense	distal	6	no	14.303	14.260	PhosphoSitePlus;EPSD	COSMIC	1.272	Down-regulation
Atypical_PDHK_PDHK_PDK4_ST	P29803	PDHA2	Q16654	PDK4	S298	D294Y	294	Missense	distal	-4	no	14.303	14.116	PhosphoSitePlus;EPSD	COSMIC;GDSC;CCLE	1.272	Down-regulation
Other_PLK_SAK_PLK4_ST	O00444	PLK4	O00444	PLK4	S22	G21R	21	Missense	proximal	-1	no	540.424	538.786	PhosphoSitePlus;EPSD	COSMIC	416.076	Down-regulation
Other_PLK_SAK_PLK4_ST	O00444	PLK4	O00444	PLK4	S22	F23Y	23	Missense	proximal	1	no	540.424	404.879	PhosphoSitePlus;EPSD	COSMIC;GDSC;CCLE	416.076	Loss
Other_PLK_SAK_PLK4_ST	O00444	PLK4	O00444	PLK4	S22	G19C	19	Missense	distal	-3	no	540.424	519.478	PhosphoSitePlus;EPSD	COSMIC	416.076	Down-regulation
Other_PLK_SAK_PLK4_ST	O00444	PLK4	O00444	PLK4	S22	G25V	25	Missense	distal	3	no	540.424	521.356	PhosphoSitePlus;EPSD	COSMIC;CCLE	416.076	Down-regulation
Other_PLK_SAK_PLK4_ST	O00444	PLK4	O00444	PLK4	S270	L276V	276	Missense	distal	6	no	525.521	467.837	EPSD	COSMIC;GDSC;CCLE	416.076	Down-regulation
Other_PLK_SAK_PLK4_ST	O00444	PLK4	O00444	PLK4	S270	S269G	269	Missense	proximal	-1	no	525.521	515.332	EPSD	COSMIC	416.076	Down-regulation
Other_PLK_SAK_PLK4_ST	O00444	PLK4	O00444	PLK4	S298	S298N	298	Missense	central	0	yes	437.770	0.000	EPSD	COSMIC	416.076	Loss
Other_PLK_SAK_PLK4_ST	O00444	PLK4	O00444	PLK4	S298	T300I	300	Missense	proximal	2	no	437.770	398.177	EPSD	COSMIC	416.076	Loss
Other_PLK_SAK_PLK4_ST	O00444	PLK4	O00444	PLK4	S298	S303F	303	Missense	distal	5	no	437.770	441.478	EPSD	COSMIC	416.076	Up-regulation
Other_PLK_SAK_PLK4_ST	O00444	PLK4	O00444	PLK4	S305	S298N	298	Missense	distal	-7	no	601.221	603.228	EPSD;PhosphoSitePlus	COSMIC	416.076	Up-regulation
Other_PLK_SAK_PLK4_ST	O00444	PLK4	O00444	PLK4	S305	T300I	300	Missense	distal	-5	no	601.221	601.670	EPSD;PhosphoSitePlus	COSMIC	416.076	Up-regulation
Other_PLK_SAK_PLK4_ST	O00444	PLK4	O00444	PLK4	S305	S303F	303	Missense	proximal	-2	no	601.221	468.869	EPSD;PhosphoSitePlus	COSMIC	416.076	Down-regulation
Other_PLK_SAK_PLK4_ST	O00444	PLK4	O00444	PLK4	S378	S379F	379	Missense	proximal	1	no	369.762	442.867	EPSD	COSMIC	416.076	Gain
Other_PLK_SAK_PLK4_ST	O00444	PLK4	O00444	PLK4	S421	P422L	422	Missense	proximal	1	no	234.690	467.627	EPSD	COSMIC	416.076	Gain
Other_PLK_SAK_PLK4_ST	P61160	ACTR2	O00444	PLK4	S66	R65L	65	Missense	proximal	-1	no	424.516	432.149	EPSD	COSMIC	416.076	Up-regulation
Other_PLK_SAK_PLK4_ST	Q9HC77	CENPJ	O00444	PLK4	S595	I600F	600	Missense	distal	5	no	529.474	532.997	PhosphoSitePlus	COSMIC	416.076	Up-regulation
Other_PLK_SAK_PLK4_ST	Q9HC77	CENPJ	O00444	PLK4	S660	L661F	661	Missense	proximal	1	no	472.220	456.954	EPSD	COSMIC;GDSC;CCLE	416.076	Down-regulation
Other_PLK_SAK_PLK4_ST	Q9HC77	CENPJ	O00444	PLK4	S662	L661F	661	Missense	proximal	-1	no	423.146	416.646	EPSD	COSMIC;GDSC;CCLE	416.076	Down-regulation
Other_PLK_SAK_PLK4_ST	Q9HC77	CENPJ	O00444	PLK4	S717	D720A	720	Missense	distal	3	no	401.231	446.451	EPSD	COSMIC;GDSC;CCLE	416.076	Gain
Other_PLK_SAK_PLK4_ST	Q969U6	FBXW5	O00444	PLK4	S151	S151L	151	Missense	central	0	yes	614.676	0.000	PhosphoSitePlus	COSMIC;GDSC;CCLE	416.076	Loss
Other_PLK_SAK_PLK4_ST	Q969U6	FBXW5	O00444	PLK4	S151	V158A	158	Missense	distal	7	no	614.676	623.773	PhosphoSitePlus	COSMIC	416.076	Up-regulation
Other_PLK_SAK_PLK4_ST	Q15154	PCM1	O00444	PLK4	S330	V332I	332	Missense	proximal	2	no	415.893	423.766	EPSD	COSMIC	416.076	Gain
Other_PLK_SAK_PLK4_ST	Q15154	PCM1	O00444	PLK4	T441	D437Y	437	Missense	distal	-4	no	416.129	369.357	EPSD	COSMIC	416.076	Loss
Other_PLK_SAK_PLK4_ST	Q15154	PCM1	O00444	PLK4	T441	S440C	440	Missense	proximal	-1	no	416.129	391.438	EPSD	COSMIC	416.076	Loss
Other_PLK_SAK_PLK4_ST	Q15154	PCM1	O00444	PLK4	S471	S471F	471	Missense	central	0	yes	426.015	0.000	EPSD	COSMIC	416.076	Loss
Other_PLK_SAK_PLK4_ST	Q15154	PCM1	O00444	PLK4	S471	V473A	473	Missense	proximal	2	no	426.015	473.801	EPSD	COSMIC	416.076	Up-regulation
Other_PLK_SAK_PLK4_ST	Q15154	PCM1	O00444	PLK4	S588	N586I	586	Missense	proximal	-2	no	513.967	399.686	EPSD	COSMIC	416.076	Loss
Other_PLK_SAK_PLK4_ST	Q15154	PCM1	O00444	PLK4	S634	E627V	627	Missense	distal	-7	no	419.661	410.728	EPSD	COSMIC	416.076	Loss
Other_PLK_SAK_PLK4_ST	Q15154	PCM1	O00444	PLK4	S637	S643I	643	Missense	distal	6	no	442.163	393.696	EPSD	COSMIC	416.076	Loss
Other_PLK_SAK_PLK4_ST	Q15154	PCM1	O00444	PLK4	S637	S644I	644	Missense	distal	7	no	442.163	435.144	EPSD	COSMIC	416.076	Down-regulation
Other_PLK_SAK_PLK4_ST	Q15154	PCM1	O00444	PLK4	S637	S644N	644	Missense	distal	7	no	442.163	436.284	EPSD	COSMIC	416.076	Down-regulation
Other_PLK_SAK_PLK4_ST	Q15154	PCM1	O00444	PLK4	S639	S643I	643	Missense	distal	4	no	450.315	408.637	EPSD	COSMIC	416.076	Loss
Other_PLK_SAK_PLK4_ST	Q15154	PCM1	O00444	PLK4	S639	S644I	644	Missense	distal	5	no	450.315	450.499	EPSD	COSMIC	416.076	Up-regulation
Other_PLK_SAK_PLK4_ST	Q15154	PCM1	O00444	PLK4	S639	S644N	644	Missense	distal	5	no	450.315	447.699	EPSD	COSMIC	416.076	Down-regulation
Other_PLK_SAK_PLK4_ST	Q15154	PCM1	O00444	PLK4	S694	D698N	698	Missense	distal	4	no	449.069	458.931	EPSD	COSMIC	416.076	Up-regulation
Other_PLK_SAK_PLK4_ST	Q15154	PCM1	O00444	PLK4	T724	K722E	722	Missense	proximal	-2	no	343.727	417.574	EPSD	COSMIC	416.076	Gain
Other_PLK_SAK_PLK4_ST	Q15154	PCM1	O00444	PLK4	T1532	E1535Q	1535	Missense	distal	3	no	437.175	402.566	EPSD	COSMIC	416.076	Loss
Other_PLK_SAK_PLK4_ST	Q15154	PCM1	O00444	PLK4	T1532	R1529H	1529	Missense	distal	-3	no	437.175	431.626	EPSD	COSMIC	416.076	Down-regulation
Other_PLK_SAK_PLK4_ST	Q15154	PCM1	O00444	PLK4	T1557	V1559I	1559	Missense	proximal	2	no	491.695	499.567	EPSD	COSMIC	416.076	Up-regulation
Other_PLK_SAK_PLK4_ST	Q15154	PCM1	O00444	PLK4	T1557	T1558A	1558	Missense	proximal	1	no	491.695	438.957	EPSD	COSMIC	416.076	Down-regulation
Other_PLK_SAK_PLK4_ST	Q15154	PCM1	O00444	PLK4	T1557	E1563K	1563	Missense	distal	6	no	491.695	425.185	EPSD	COSMIC	416.076	Down-regulation
Other_PLK_SAK_PLK4_ST	Q15154	PCM1	O00444	PLK4	S1697	I1698L	1698	Missense	proximal	1	no	422.117	465.707	EPSD	COSMIC	416.076	Up-regulation
Other_PLK_SAK_PLK4_ST	Q15154	PCM1	O00444	PLK4	S1786	K1787T	1787	Missense	proximal	1	no	499.236	659.072	EPSD	COSMIC	416.076	Up-regulation
Other_PLK_SAK_PLK4_ST	Q15154	PCM1	O00444	PLK4	S1786	I1783V	1783	Missense	distal	-3	no	499.236	497.452	EPSD	COSMIC	416.076	Down-regulation
Other_PLK_SAK_PLK4_ST	Q15468	STIL	O00444	PLK4	T557	L558P	558	Missense	proximal	1	no	444.543	211.606	EPSD	COSMIC;GDSC;CCLE	416.076	Loss
Other_PLK_SAK_PLK4_ST	Q15468	STIL	O00444	PLK4	T557	P555L	555	Missense	proximal	-2	no	444.543	540.219	EPSD	COSMIC	416.076	Up-regulation
Other_PLK_SAK_PLK4_ST	Q15468	STIL	O00444	PLK4	S1108	T1104A	1104	Missense	distal	-4	no	475.878	491.536	EPSD	COSMIC	416.076	Up-regulation
Other_PLK_SAK_PLK4_ST	Q15468	STIL	O00444	PLK4	S1108	S1103G	1103	Missense	distal	-5	no	475.878	475.897	EPSD	COSMIC	416.076	Up-regulation
Other_PLK_SAK_PLK4_ST	Q15468	STIL	O00444	PLK4	S1116	M1123I	1123	Missense	distal	7	no	534.561	531.392	PhosphoSitePlus	COSMIC	416.076	Down-regulation
Other_PLK_SAK_PLK4_ST	Q15468	STIL	O00444	PLK4	S1116	T1119I	1119	Missense	distal	3	no	534.561	503.585	PhosphoSitePlus	COSMIC	416.076	Down-regulation
Other_PLK_SAK_PLK4_ST	Q15468	STIL	O00444	PLK4	S1116	K1121N	1121	Missense	distal	5	no	534.561	528.429	PhosphoSitePlus	COSMIC	416.076	Down-regulation
Other_PLK_SAK_PLK4_ST	Q15468	STIL	O00444	PLK4	T1273	K1278E	1278	Missense	distal	5	no	461.006	457.240	EPSD	COSMIC	416.076	Down-regulation
Other_PLK_SAK_PLK4_ST	Q15468	STIL	O00444	PLK4	T1273	S1270L	1270	Missense	distal	-3	no	461.006	459.720	EPSD	COSMIC	416.076	Down-regulation
Other_PLK_SAK_PLK4_ST	Q15468	STIL	O00444	PLK4	T1273	N1266D	1266	Missense	distal	-7	no	461.006	455.748	EPSD	COSMIC	416.076	Down-regulation
Other_PLK_SAK_PLK4_ST	Q15468	STIL	O00444	PLK4	T1273	R1279H	1279	Missense	distal	6	no	461.006	406.176	EPSD	COSMIC	416.076	Loss
Other_PLK_SAK_PLK4_ST	O43303	CCP110	O00444	PLK4	S21	P27L	27	Missense	distal	6	no	381.485	477.575	EPSD	COSMIC	416.076	Gain
Other_PLK_SAK_PLK4_ST	O43303	CCP110	O00444	PLK4	S24	P27L	27	Missense	distal	3	no	504.720	591.579	EPSD	COSMIC	416.076	Up-regulation
Other_PLK_SAK_PLK4_ST	O43303	CCP110	O00444	PLK4	S247	R254K	254	Missense	distal	7	no	464.522	461.186	EPSD	COSMIC	416.076	Down-regulation
Other_PLK_SAK_PLK4_ST	O43303	CCP110	O00444	PLK4	T382	R379C	379	Missense	distal	-3	no	478.780	457.389	EPSD	COSMIC	416.076	Down-regulation
Other_PLK_SAK_PLK4_ST	O43303	CCP110	O00444	PLK4	S912	Q916H	916	Missense	distal	4	no	426.498	430.636	EPSD	COSMIC	416.076	Up-regulation
Other_PLK_SAK_PLK4_ST	O43303	CCP110	O00444	PLK4	S912	P907S	907	Missense	distal	-5	no	426.498	425.783	EPSD	COSMIC	416.076	Down-regulation
Other_PLK_SAK_PLK4_ST	O43303	CCP110	O00444	PLK4	S918	Q916H	916	Missense	proximal	-2	no	447.637	506.703	EPSD	COSMIC	416.076	Up-regulation
AGC_DMPK_CRIK_CIT_ST	P24844	MYL9	O14578	CIT	T11	P15S	15	Missense	distal	4	no	0.458	0.451	EPSD	COSMIC	0.226	Down-regulation
AGC_DMPK_CRIK_CIT_ST	P24844	MYL9	O14578	CIT	T11	R14Q	14	Missense	distal	3	no	0.458	0.446	EPSD	COSMIC	0.226	Down-regulation
AGC_DMPK_CRIK_CIT_ST	P24844	MYL9	O14578	CIT	T19	N21T	21	Missense	proximal	2	no	6.379	6.369	PhosphoSitePlus;EPSD	COSMIC	0.226	Down-regulation
AGC_DMPK_CRIK_CIT_ST	P24844	MYL9	O14578	CIT	T19	P15S	15	Missense	distal	-4	no	6.379	6.381	PhosphoSitePlus;EPSD	COSMIC	0.226	Up-regulation
AGC_DMPK_CRIK_CIT_ST	P24844	MYL9	O14578	CIT	T19	R14Q	14	Missense	distal	-5	no	6.379	6.357	PhosphoSitePlus;EPSD	COSMIC	0.226	Down-regulation
AGC_DMPK_CRIK_CIT_ST	P24844	MYL9	O14578	CIT	S20	N21T	21	Missense	proximal	1	no	6.070	5.920	EPSD;PhosphoSitePlus	COSMIC	0.226	Down-regulation
AGC_DMPK_CRIK_CIT_ST	P24844	MYL9	O14578	CIT	S20	P15S	15	Missense	distal	-5	no	6.070	6.042	EPSD;PhosphoSitePlus	COSMIC	0.226	Down-regulation
AGC_DMPK_CRIK_CIT_ST	P24844	MYL9	O14578	CIT	S20	R14Q	14	Missense	distal	-6	no	6.070	5.874	EPSD;PhosphoSitePlus	COSMIC	0.226	Down-regulation
Other_Aur_AURKC_ST	Q9NQS7	INCENP	Q9UQB9	AURKC	S72	R70Q	70	Missense	proximal	-2	no	20.122	11.743	EPSD	COSMIC;CCLE	14.093	Loss
Other_Aur_AURKC_ST	Q9NQS7	INCENP	Q9UQB9	AURKC	S91	R92Q	92	Missense	proximal	1	no	19.994	18.025	EPSD	COSMIC	14.093	Down-regulation
Other_Aur_AURKC_ST	Q9NQS7	INCENP	Q9UQB9	AURKC	S94	R92Q	92	Missense	proximal	-2	no	18.704	10.325	EPSD	COSMIC	14.093	Loss
Other_Aur_AURKC_ST	Q9NQS7	INCENP	Q9UQB9	AURKC	T184	E180K	180	Missense	distal	-4	no	19.442	19.130	EPSD	COSMIC	14.093	Down-regulation
Other_Aur_AURKC_ST	Q9NQS7	INCENP	Q9UQB9	AURKC	T207	T204I	204	Missense	distal	-3	no	17.060	15.725	EPSD	COSMIC;GDSC;CCLE	14.093	Down-regulation
Other_Aur_AURKC_ST	Q9NQS7	INCENP	Q9UQB9	AURKC	S223	P220H	220	Missense	distal	-3	no	12.370	14.383	EPSD	COSMIC	14.093	Gain
Other_Aur_AURKC_ST	Q9NQS7	INCENP	Q9UQB9	AURKC	S234	S234G	234	Missense	central	0	yes	20.731	0.000	EPSD	COSMIC	14.093	Loss
Other_Aur_AURKC_ST	Q9NQS7	INCENP	Q9UQB9	AURKC	S263	P264T	264	Missense	proximal	1	no	12.548	14.721	EPSD	COSMIC	14.093	Gain
Other_Aur_AURKC_ST	Q9NQS7	INCENP	Q9UQB9	AURKC	S269	S269L	269	Missense	central	0	yes	15.126	0.000	EPSD	COSMIC;GDSC	14.093	Loss
Other_Aur_AURKC_ST	Q9NQS7	INCENP	Q9UQB9	AURKC	S269	P264T	264	Missense	distal	-5	no	15.126	15.069	EPSD	COSMIC	14.093	Down-regulation
Other_Aur_AURKC_ST	Q9NQS7	INCENP	Q9UQB9	AURKC	S269	P276L	276	Missense	distal	7	no	15.126	15.472	EPSD	COSMIC	14.093	Up-regulation
Other_Aur_AURKC_ST	Q9NQS7	INCENP	Q9UQB9	AURKC	S269	P276S	276	Missense	distal	7	no	15.126	15.122	EPSD	COSMIC	14.093	Down-regulation
Other_Aur_AURKC_ST	Q9NQS7	INCENP	Q9UQB9	AURKC	S306	V303G	303	Missense	distal	-3	no	18.471	18.959	EPSD	COSMIC;GDSC	14.093	Up-regulation
Other_Aur_AURKC_ST	Q9NQS7	INCENP	Q9UQB9	AURKC	S306	D299N	299	Missense	distal	-7	no	18.471	18.085	EPSD	COSMIC	14.093	Down-regulation
Other_Aur_AURKC_ST	Q9NQS7	INCENP	Q9UQB9	AURKC	S306	P310L	310	Missense	distal	4	no	18.471	18.044	EPSD	COSMIC	14.093	Down-regulation
Other_Aur_AURKC_ST	Q9NQS7	INCENP	Q9UQB9	AURKC	S306	P313Q	313	Missense	distal	7	no	18.471	18.745	EPSD	COSMIC	14.093	Up-regulation
Other_Aur_AURKC_ST	Q9NQS7	INCENP	Q9UQB9	AURKC	S306	S311F	311	Missense	distal	5	no	18.471	18.571	EPSD	COSMIC	14.093	Up-regulation
Other_Aur_AURKC_ST	Q9NQS7	INCENP	Q9UQB9	AURKC	S336	R333C	333	Missense	distal	-3	no	18.620	17.258	EPSD	COSMIC	14.093	Down-regulation
Other_Aur_AURKC_ST	Q9NQS7	INCENP	Q9UQB9	AURKC	S336	V332F	332	Missense	distal	-4	no	18.620	18.637	EPSD	COSMIC	14.093	Up-regulation
Other_Aur_AURKC_ST	Q9NQS7	INCENP	Q9UQB9	AURKC	S336	R337T	337	Missense	proximal	1	no	18.620	18.304	EPSD	COSMIC	14.093	Down-regulation
Other_Aur_AURKC_ST	Q9NQS7	INCENP	Q9UQB9	AURKC	S421	G428W	428	Missense	distal	7	no	16.139	16.324	EPSD	COSMIC;CCLE	14.093	Up-regulation
Other_Aur_AURKC_ST	Q9NQS7	INCENP	Q9UQB9	AURKC	S486	R490L	490	Missense	distal	4	no	15.849	14.752	EPSD	COSMIC	14.093	Down-regulation
Other_Aur_AURKC_ST	Q9NQS7	INCENP	Q9UQB9	AURKC	S486	R493W	493	Missense	distal	7	no	15.849	16.002	EPSD	COSMIC	14.093	Up-regulation
Other_Aur_AURKC_ST	Q9NQS7	INCENP	Q9UQB9	AURKC	T524	S518Y	518	Missense	distal	-6	no	19.996	20.313	EPSD	COSMIC	14.093	Up-regulation
Other_Aur_AURKC_ST	Q9NQS7	INCENP	Q9UQB9	AURKC	T524	S518F	518	Missense	distal	-6	no	19.996	20.362	EPSD	COSMIC	14.093	Up-regulation
Other_Aur_AURKC_ST	O15392	BIRC5	Q9UQB9	AURKC	S20	H17R	17	Missense	distal	-3	no	28.038	27.975	PhosphoSitePlus	COSMIC	14.093	Down-regulation
Other_Aur_AURKC_ST	O15392	BIRC5	Q9UQB9	AURKC	S82	H77Q	77	Missense	distal	-5	no	14.197	14.194	EPSD	COSMIC	14.093	Down-regulation
Other_Aur_AURKC_ST	O15392	BIRC5	Q9UQB9	AURKC	T117	I113V	113	Missense	distal	-4	no	16.936	17.163	EPSD	COSMIC	14.093	Up-regulation
Other_Aur_AURKC_ST	O75410	TACC1	Q9UQB9	AURKC	S20	G24S	24	Missense	distal	4	no	13.001	14.143	EPSD	COSMIC	14.093	Gain
Other_Aur_AURKC_ST	O75410	TACC1	Q9UQB9	AURKC	S91	S94A	94	Missense	distal	3	no	15.108	15.309	EPSD	COSMIC	14.093	Up-regulation
Other_Aur_AURKC_ST	O75410	TACC1	Q9UQB9	AURKC	S91	A85S	85	Missense	distal	-6	no	15.108	14.942	EPSD	COSMIC	14.093	Down-regulation
Other_Aur_AURKC_ST	O75410	TACC1	Q9UQB9	AURKC	S118	S118L	118	Missense	central	0	yes	14.331	0.000	EPSD	COSMIC	14.093	Loss
Other_Aur_AURKC_ST	O75410	TACC1	Q9UQB9	AURKC	S118	S118P	118	Missense	central	0	yes	14.331	0.000	EPSD	COSMIC	14.093	Loss
Other_Aur_AURKC_ST	O75410	TACC1	Q9UQB9	AURKC	S118	S111F	111	Missense	distal	-7	no	14.331	14.871	EPSD	COSMIC	14.093	Up-regulation
Other_Aur_AURKC_ST	O75410	TACC1	Q9UQB9	AURKC	S179	G180W	180	Missense	proximal	1	no	13.958	14.124	EPSD	COSMIC	14.093	Gain
Other_Aur_AURKC_ST	O75410	TACC1	Q9UQB9	AURKC	S228	S228C	228	Missense	central	0	yes	33.505	0.000	PhosphoSitePlus	COSMIC	14.093	Loss
Other_Aur_AURKC_ST	O75410	TACC1	Q9UQB9	AURKC	S228	P233S	233	Missense	distal	5	no	33.505	33.465	PhosphoSitePlus	COSMIC	14.093	Down-regulation
Other_Aur_AURKC_ST	O75410	TACC1	Q9UQB9	AURKC	T294	E293K	293	Missense	proximal	-1	no	13.681	16.532	EPSD	COSMIC	14.093	Gain
Other_Aur_AURKC_ST	O75410	TACC1	Q9UQB9	AURKC	T297	S299L	299	Missense	proximal	2	no	13.660	14.461	EPSD	COSMIC	14.093	Gain
Other_Aur_AURKC_ST	O75410	TACC1	Q9UQB9	AURKC	S299	G306D	306	Missense	distal	7	no	14.024	14.414	EPSD	COSMIC	14.093	Gain
Other_Aur_AURKC_ST	O75410	TACC1	Q9UQB9	AURKC	T302	G306D	306	Missense	distal	4	no	14.145	14.200	EPSD	COSMIC	14.093	Up-regulation
Other_Aur_AURKC_ST	O75410	TACC1	Q9UQB9	AURKC	T302	S299L	299	Missense	distal	-3	no	14.145	13.057	EPSD	COSMIC	14.093	Loss
Other_Aur_AURKC_ST	O75410	TACC1	Q9UQB9	AURKC	S313	E311K	311	Missense	proximal	-2	no	7.078	15.494	EPSD	COSMIC	14.093	Gain
Other_Aur_AURKC_ST	O75410	TACC1	Q9UQB9	AURKC	S315	E311K	311	Missense	distal	-4	no	14.898	14.587	EPSD	COSMIC	14.093	Down-regulation
Other_Aur_AURKC_ST	O75410	TACC1	Q9UQB9	AURKC	S315	E312Q	312	Missense	distal	-3	no	14.898	14.784	EPSD	COSMIC	14.093	Down-regulation
Other_Aur_AURKC_ST	O75410	TACC1	Q9UQB9	AURKC	S315	S316F	316	Missense	proximal	1	no	14.898	12.819	EPSD	COSMIC	14.093	Loss
Other_Aur_AURKC_ST	O75410	TACC1	Q9UQB9	AURKC	S315	S315F	315	Missense	central	0	yes	14.898	0.000	EPSD	COSMIC	14.093	Loss
Other_Aur_AURKC_ST	O75410	TACC1	Q9UQB9	AURKC	S315	E311Q	311	Missense	distal	-4	no	14.898	14.789	EPSD	COSMIC	14.093	Down-regulation
Other_Aur_AURKC_ST	O75410	TACC1	Q9UQB9	AURKC	S361	S361F	361	Missense	central	0	yes	14.188	0.000	EPSD	COSMIC	14.093	Loss
Other_Aur_AURKC_ST	O75410	TACC1	Q9UQB9	AURKC	S361	A362T	362	Missense	proximal	1	no	14.188	13.246	EPSD	COSMIC	14.093	Loss
Other_Aur_AURKC_ST	O75410	TACC1	Q9UQB9	AURKC	S361	G357D	357	Missense	distal	-4	no	14.188	14.425	EPSD	COSMIC	14.093	Up-regulation
Other_Aur_AURKC_ST	O75410	TACC1	Q9UQB9	AURKC	S361	E365K	365	Missense	distal	4	no	14.188	15.764	EPSD	COSMIC	14.093	Up-regulation
Other_Aur_AURKC_ST	O75410	TACC1	Q9UQB9	AURKC	T504	S511F	511	Missense	distal	7	no	14.606	15.081	EPSD	COSMIC	14.093	Up-regulation
Other_Aur_AURKC_ST	O75410	TACC1	Q9UQB9	AURKC	T504	E507K	507	Missense	distal	3	no	14.606	14.443	EPSD	COSMIC	14.093	Down-regulation
Other_Aur_AURKC_ST	O75410	TACC1	Q9UQB9	AURKC	S660	Q657R	657	Missense	distal	-3	no	16.478	18.131	EPSD	COSMIC	14.093	Up-regulation
Other_Aur_AURKC_ST	O75410	TACC1	Q9UQB9	AURKC	S759	A761S	761	Missense	proximal	2	no	15.038	14.587	EPSD	COSMIC	14.093	Down-regulation
Other_Aur_AURKC_ST	O75410	TACC1	Q9UQB9	AURKC	S759	H763N	763	Missense	distal	4	no	15.038	15.436	EPSD	COSMIC	14.093	Up-regulation
Other_Aur_AURKC_ST	O75410	TACC1	Q9UQB9	AURKC	S759	A760V	760	Missense	proximal	1	no	15.038	12.551	EPSD	COSMIC	14.093	Loss
Other_Aur_AURKC_ST	O75410	TACC1	Q9UQB9	AURKC	S759	L766V	766	Missense	distal	7	no	15.038	15.346	EPSD	COSMIC	14.093	Up-regulation
Other_Aur_AURKC_ST	P25963	NFKBIA	Q9UQB9	AURKC	S32	M37K	37	Missense	distal	5	no	31.679	31.598	PhosphoSitePlus	COSMIC	14.093	Down-regulation
Other_Aur_AURKC_ST	P25963	NFKBIA	Q9UQB9	AURKC	S32	S36P	36	Missense	distal	4	no	31.679	30.730	PhosphoSitePlus	COSMIC	14.093	Down-regulation
Other_Aur_AURKC_ST	P25963	NFKBIA	Q9UQB9	AURKC	S32	S32N	32	Missense	central	0	yes	31.679	0.000	PhosphoSitePlus	COSMIC	14.093	Loss
Other_Aur_AURKC_ST	P25963	NFKBIA	Q9UQB9	AURKC	S293	T291K	291	Missense	proximal	-2	no	12.162	14.433	EPSD	COSMIC	14.093	Gain
STE_STE7_MEK7_MAP2K7_ST	P45984	MAPK9	O14733	MAP2K7	T183	R189W	189	Missense	distal	6	no	8.801	8.806	EPSD;PhosphoSitePlus	COSMIC	2.107	Up-regulation
STE_STE7_MEK7_MAP2K7_ST	P45984	MAPK9	O14733	MAP2K7	T183	R189Q	189	Missense	distal	6	no	8.801	8.730	EPSD;PhosphoSitePlus	COSMIC	2.107	Down-regulation
STE_STE7_MEK7_MAP2K7_ST	P45984	MAPK9	O14733	MAP2K7	S390	A385T	385	Missense	distal	-5	no	2.742	2.678	EPSD	COSMIC	2.107	Down-regulation
STE_STE7_MEK7_MAP2K7_ST	P45984	MAPK9	O14733	MAP2K7	S390	P387L	387	Missense	distal	-3	no	2.742	2.745	EPSD	COSMIC	2.107	Up-regulation
STE_STE7_MEK7_MAP2K7_ST	P53779	MAPK10	O14733	MAP2K7	T221	A214V	214	Missense	distal	-7	no	9.126	9.084	PhosphoSitePlus	COSMIC	2.107	Down-regulation
STE_STE7_MEK7_MAP2K7_ST	P53779	MAPK10	O14733	MAP2K7	T221	V225L	225	Missense	distal	4	no	9.126	8.430	PhosphoSitePlus	COSMIC	2.107	Down-regulation
STE_STE7_MEK7_MAP2K7_ST	P53779	MAPK10	O14733	MAP2K7	T221	R227C	227	Missense	distal	6	no	9.126	9.083	PhosphoSitePlus	COSMIC	2.107	Down-regulation
STE_STE7_MEK7_MAP2K7_ST	P53779	MAPK10	O14733	MAP2K7	T221	G215D	215	Missense	distal	-6	no	9.126	8.726	PhosphoSitePlus	COSMIC	2.107	Down-regulation
STE_STE7_MEK7_MAP2K7_ST	P53779	MAPK10	O14733	MAP2K7	T221	P222L	222	Missense	proximal	1	no	9.126	8.793	PhosphoSitePlus	COSMIC	2.107	Down-regulation
STE_STE7_MEK7_MAP2K7_ST	P45983	MAPK8	O14733	MAP2K7	T183	G177R	177	Missense	distal	-6	no	9.246	9.043	PhosphoSitePlus;EPSD	COSMIC	2.107	Down-regulation
STE_STE7_MEK7_MAP2K7_ST	P45983	MAPK8	O14733	MAP2K7	T183	R189G	189	Missense	distal	6	no	9.246	9.238	PhosphoSitePlus;EPSD	COSMIC	2.107	Down-regulation
STE_STE7_MEK7_MAP2K7_ST	P45983	MAPK8	O14733	MAP2K7	T183	G177K	177	Missense	distal	-6	no	9.246	9.141	PhosphoSitePlus;EPSD	COSMIC	2.107	Down-regulation
STE_STE7_MEK7_MAP2K7_ST	P45983	MAPK8	O14733	MAP2K7	T183	T183A	183	Missense	central	0	yes	9.246	0.000	PhosphoSitePlus;EPSD	COSMIC	2.107	Loss
STE_STE7_MEK7_MAP2K7_ST	Q13158	FADD	O14733	MAP2K7	S194	S194F	194	Missense	central	0	yes	5.970	0.000	PhosphoSitePlus	COSMIC	2.107	Loss
STE_STE7_MEK7_MAP2K7_ST	Q13158	FADD	O14733	MAP2K7	S197	S194F	194	Missense	distal	-3	no	2.596	2.712	EPSD	COSMIC	2.107	Up-regulation
TK_Src_Frk_FRK_Y	P38398	BRCA1	P42685	FRK	Y1552	D1546Y	1546	Missense	distal	-6	no	8.438	8.571	PhosphoSitePlus	COSMIC	2.774	Up-regulation
TK_Src_Frk_FRK_Y	P38398	BRCA1	P42685	FRK	Y1552	D1546N	1546	Missense	distal	-6	no	8.438	8.353	PhosphoSitePlus	COSMIC;GDSC	2.774	Down-regulation
TK_Src_Frk_FRK_Y	P38398	BRCA1	P42685	FRK	Y1552	S1551C	1551	Missense	proximal	-1	no	8.438	8.750	PhosphoSitePlus	COSMIC	2.774	Up-regulation
TK_Src_Frk_FRK_Y	P38398	BRCA1	P42685	FRK	Y1552	L1558I	1558	Missense	distal	6	no	8.438	8.456	PhosphoSitePlus	COSMIC	2.774	Up-regulation
TK_Src_Frk_FRK_Y	P38398	BRCA1	P42685	FRK	Y1552	L1547F	1547	Missense	distal	-5	no	8.438	8.439	PhosphoSitePlus	COSMIC	2.774	Up-regulation
TK_Src_Frk_FRK_Y	P38398	BRCA1	P42685	FRK	Y1552	S1551T	1551	Missense	proximal	-1	no	8.438	8.779	PhosphoSitePlus	COSMIC	2.774	Up-regulation
TK_Src_Frk_FRK_Y	P38398	BRCA1	P42685	FRK	Y1563	S1569G	1569	Missense	distal	6	no	3.100	3.209	EPSD	COSMIC	2.774	Up-regulation
TK_Src_Frk_FRK_Y	P38398	BRCA1	P42685	FRK	Y1563	L1564P	1564	Missense	proximal	1	no	3.100	2.634	EPSD	COSMIC	2.774	Loss
TK_Src_Frk_FRK_Y	P38398	BRCA1	P42685	FRK	Y1563	L1558I	1558	Missense	distal	-5	no	3.100	3.097	EPSD	COSMIC	2.774	Down-regulation
TK_Src_Frk_FRK_Y	P38398	BRCA1	P42685	FRK	Y1563	P1562L	1562	Missense	proximal	-1	no	3.100	3.127	EPSD	COSMIC	2.774	Up-regulation
TK_Src_Frk_FRK_Y	P38398	BRCA1	P42685	FRK	Y1563	L1570P	1570	Missense	distal	7	no	3.100	3.088	EPSD	COSMIC	2.774	Down-regulation
TK_Src_Frk_FRK_Y	P38398	BRCA1	P42685	FRK	Y1563	P1562T	1562	Missense	proximal	-1	no	3.100	3.129	EPSD	COSMIC	2.774	Up-regulation
TK_Src_Frk_FRK_Y	P38398	BRCA1	P42685	FRK	Y1563	I1568S	1568	Missense	distal	5	no	3.100	3.106	EPSD	COSMIC	2.774	Up-regulation
TK_Src_Frk_FRK_Y	P38398	BRCA1	P42685	FRK	Y1563	S1566G	1566	Missense	distal	3	no	3.100	3.142	EPSD	COSMIC	2.774	Up-regulation
TK_Src_Frk_FRK_Y	P60484	PTEN	P42685	FRK	Y155	L152V	152	Missense	distal	-3	no	2.445	2.805	EPSD	COSMIC	2.774	Gain
TK_Src_Frk_FRK_Y	P60484	PTEN	P42685	FRK	Y155	L152Q	152	Missense	distal	-3	no	2.445	3.027	EPSD	COSMIC	2.774	Gain
TK_Src_Frk_FRK_Y	P60484	PTEN	P42685	FRK	Y155	L152I	152	Missense	distal	-3	no	2.445	2.816	EPSD	COSMIC	2.774	Gain
TK_Src_Frk_FRK_Y	P60484	PTEN	P42685	FRK	Y336	N334D	334	Missense	proximal	-2	no	10.404	10.472	PhosphoSitePlus	COSMIC	2.774	Up-regulation
TK_Src_Frk_FRK_Y	P60484	PTEN	P42685	FRK	Y336	F337L	337	Missense	proximal	1	no	10.404	10.596	PhosphoSitePlus	COSMIC	2.774	Up-regulation
TK_Src_Frk_FRK_Y	P60484	PTEN	P42685	FRK	Y336	F341L	341	Missense	distal	5	no	10.404	10.454	PhosphoSitePlus	COSMIC	2.774	Up-regulation
TK_Src_Frk_FRK_Y	P60484	PTEN	P42685	FRK	Y336	P339S	339	Missense	distal	3	no	10.404	10.375	PhosphoSitePlus	COSMIC	2.774	Down-regulation
TK_Src_Frk_FRK_Y	P60484	PTEN	P42685	FRK	Y336	S338Y	338	Missense	proximal	2	no	10.404	9.287	PhosphoSitePlus	COSMIC	2.774	Down-regulation
TK_Src_Frk_FRK_Y	P60484	PTEN	P42685	FRK	Y336	F341I	341	Missense	distal	5	no	10.404	10.374	PhosphoSitePlus	COSMIC	2.774	Down-regulation
TK_Src_Frk_FRK_Y	P60484	PTEN	P42685	FRK	Y336	F341Y	341	Missense	distal	5	no	10.404	10.395	PhosphoSitePlus	COSMIC	2.774	Down-regulation
TK_Src_Frk_FRK_Y	P60484	PTEN	P42685	FRK	Y336	P339L	339	Missense	distal	3	no	10.404	10.435	PhosphoSitePlus	COSMIC	2.774	Up-regulation
TK_Src_Frk_FRK_Y	P60484	PTEN	P42685	FRK	Y336	N334S	334	Missense	proximal	-2	no	10.404	10.393	PhosphoSitePlus	COSMIC	2.774	Down-regulation
TK_Src_Frk_FRK_Y	P60484	PTEN	P42685	FRK	Y336	S338T	338	Missense	proximal	2	no	10.404	9.320	PhosphoSitePlus	COSMIC	2.774	Down-regulation
TK_Src_Frk_FRK_Y	P60484	PTEN	P42685	FRK	Y336	N334Y	334	Missense	proximal	-2	no	10.404	10.424	PhosphoSitePlus	COSMIC	2.774	Up-regulation
TK_Src_Frk_FRK_Y	P60484	PTEN	P42685	FRK	Y336	D331H	331	Missense	distal	-5	no	10.404	10.402	PhosphoSitePlus	COSMIC	2.774	Down-regulation
TK_Src_Frk_FRK_Y	P60484	PTEN	P42685	FRK	Y336	D331G	331	Missense	distal	-5	no	10.404	10.405	PhosphoSitePlus	COSMIC	2.774	Up-regulation
TK_Src_Frk_FRK_Y	P60484	PTEN	P42685	FRK	Y336	Y336C	336	Missense	central	0	yes	10.404	0.000	PhosphoSitePlus	COSMIC	2.774	Loss
TK_Src_Frk_FRK_Y	P60484	PTEN	P42685	FRK	Y336	V343G	343	Missense	distal	7	no	10.404	10.416	PhosphoSitePlus	COSMIC	2.774	Up-regulation
TK_Src_Frk_FRK_Y	P60484	PTEN	P42685	FRK	Y336	S338C	338	Missense	proximal	2	no	10.404	9.312	PhosphoSitePlus	COSMIC	2.774	Down-regulation
TK_Src_Frk_FRK_Y	P60484	PTEN	P42685	FRK	Y336	Y336F	336	Missense	central	0	yes	10.404	0.000	PhosphoSitePlus	COSMIC	2.774	Loss
TK_Src_Frk_FRK_Y	P60484	PTEN	P42685	FRK	Y336	A333V	333	Missense	distal	-3	no	10.404	9.987	PhosphoSitePlus	COSMIC	2.774	Down-regulation
Other_NAK_MPSK_STK16_ST	O75716	STK16	O75716	STK16	T185	A190V	190	Missense	distal	5	no	3.433	3.503	EPSD;PhosphoSitePlus	COSMIC	1.527	Up-regulation
Other_NAK_MPSK_STK16_ST	O75716	STK16	O75716	STK16	S197	A190V	190	Missense	distal	-7	no	3.400	3.389	PhosphoSitePlus;EPSD	COSMIC	1.527	Down-regulation
Other_NAK_MPSK_STK16_ST	Q9Y295	DRG1	O75716	STK16	T220	R222H	222	Missense	proximal	2	no	1.922	1.906	EPSD	COSMIC;GDSC;CCLE	1.527	Down-regulation
TK_EGFR_ERBB2_Y	O43157	PLXNB1	P04626	ERBB2	Y1708	R1712Q	1712	Missense	distal	4	no	6.099	6.040	PhosphoSitePlus;EPSD	COSMIC	2.878	Down-regulation
TK_EGFR_ERBB2_Y	O43157	PLXNB1	P04626	ERBB2	Y1708	R1712L	1712	Missense	distal	4	no	6.099	5.874	PhosphoSitePlus;EPSD	COSMIC	2.878	Down-regulation
TK_EGFR_ERBB2_Y	O43157	PLXNB1	P04626	ERBB2	Y1732	K1729N	1729	Missense	distal	-3	no	5.600	5.423	EPSD;PhosphoSitePlus	COSMIC	2.878	Down-regulation
TK_EGFR_ERBB2_Y	O43157	PLXNB1	P04626	ERBB2	Y1732	R1738C	1738	Missense	distal	6	no	5.600	5.674	EPSD;PhosphoSitePlus	COSMIC	2.878	Up-regulation
TK_EGFR_ERBB2_Y	P04626	ERBB2	P04626	ERBB2	Y877	D873G	873	Missense	distal	-4	no	5.903	5.887	EPSD;PhosphoSitePlus	COSMIC	2.878	Down-regulation
TK_EGFR_ERBB2_Y	P04626	ERBB2	P04626	ERBB2	Y877	E874D	874	Missense	distal	-3	no	5.903	5.699	EPSD;PhosphoSitePlus	COSMIC	2.878	Down-regulation
TK_EGFR_ERBB2_Y	P04626	ERBB2	P04626	ERBB2	Y877	T875I	875	Missense	proximal	-2	no	5.903	5.446	EPSD;PhosphoSitePlus	COSMIC	2.878	Down-regulation
TK_EGFR_ERBB2_Y	P04626	ERBB2	P04626	ERBB2	Y877	H878Y	878	Missense	proximal	1	no	5.903	5.598	EPSD;PhosphoSitePlus	COSMIC	2.878	Down-regulation
TK_EGFR_ERBB2_Y	P04626	ERBB2	P04626	ERBB2	Y877	D880H	880	Missense	distal	3	no	5.903	6.027	EPSD;PhosphoSitePlus	COSMIC	2.878	Up-regulation
TK_EGFR_ERBB2_Y	P04626	ERBB2	P04626	ERBB2	Y877	G882D	882	Missense	distal	5	no	5.903	6.001	EPSD;PhosphoSitePlus	COSMIC	2.878	Up-regulation
TK_EGFR_ERBB2_Y	P04626	ERBB2	P04626	ERBB2	Y877	E874K	874	Missense	distal	-3	no	5.903	5.868	EPSD;PhosphoSitePlus	COSMIC	2.878	Down-regulation
TK_EGFR_ERBB2_Y	P04626	ERBB2	P04626	ERBB2	Y877	V884M	884	Missense	distal	7	no	5.903	5.759	EPSD;PhosphoSitePlus	COSMIC	2.878	Down-regulation
TK_EGFR_ERBB2_Y	P04626	ERBB2	P04626	ERBB2	Y877	H878R	878	Missense	proximal	1	no	5.903	5.523	EPSD;PhosphoSitePlus	COSMIC	2.878	Down-regulation
TK_EGFR_ERBB2_Y	P04626	ERBB2	P04626	ERBB2	Y877	D880N	880	Missense	distal	3	no	5.903	6.076	EPSD;PhosphoSitePlus	COSMIC	2.878	Up-regulation
TK_EGFR_ERBB2_Y	P04626	ERBB2	P04626	ERBB2	Y1023	F1030C	1030	Missense	distal	7	no	5.878	5.736	EPSD;PhosphoSitePlus	COSMIC	2.878	Down-regulation
TK_EGFR_ERBB2_Y	P04626	ERBB2	P04626	ERBB2	Y1023	F1030S	1030	Missense	distal	7	no	5.878	5.589	EPSD;PhosphoSitePlus	COSMIC	2.878	Down-regulation
TK_EGFR_ERBB2_Y	P04626	ERBB2	P04626	ERBB2	Y1023	Q1027E	1027	Missense	distal	4	no	5.878	5.899	EPSD;PhosphoSitePlus	COSMIC	2.878	Up-regulation
TK_EGFR_ERBB2_Y	P04626	ERBB2	P04626	ERBB2	Y1023	P1026S	1026	Missense	distal	3	no	5.878	6.043	EPSD;PhosphoSitePlus	COSMIC	2.878	Up-regulation
TK_EGFR_ERBB2_Y	P04626	ERBB2	P04626	ERBB2	Y1112	D1105N	1105	Missense	distal	-7	no	5.879	5.690	EPSD;PhosphoSitePlus	COSMIC	2.878	Down-regulation
TK_EGFR_ERBB2_Y	P04626	ERBB2	P04626	ERBB2	Y1112	S1107N	1107	Missense	distal	-5	no	5.879	5.507	EPSD;PhosphoSitePlus	COSMIC	2.878	Down-regulation
TK_EGFR_ERBB2_Y	P04626	ERBB2	P04626	ERBB2	Y1112	P1116S	1116	Missense	distal	4	no	5.879	5.775	EPSD;PhosphoSitePlus	COSMIC	2.878	Down-regulation
TK_EGFR_ERBB2_Y	P04626	ERBB2	P04626	ERBB2	Y1112	E1114G	1114	Missense	proximal	2	no	5.879	6.094	EPSD;PhosphoSitePlus	COSMIC	2.878	Up-regulation
TK_EGFR_ERBB2_Y	P04626	ERBB2	P04626	ERBB2	Y1112	D1105Y	1105	Missense	distal	-7	no	5.879	5.507	EPSD;PhosphoSitePlus	COSMIC	2.878	Down-regulation
TK_EGFR_ERBB2_Y	P04626	ERBB2	P04626	ERBB2	Y1112	R1111Q	1111	Missense	proximal	-1	no	5.879	5.764	EPSD;PhosphoSitePlus	COSMIC	2.878	Down-regulation
TK_EGFR_ERBB2_Y	P04626	ERBB2	P04626	ERBB2	Y1112	E1114Q	1114	Missense	proximal	2	no	5.879	5.858	EPSD;PhosphoSitePlus	COSMIC	2.878	Down-regulation
TK_EGFR_ERBB2_Y	P04626	ERBB2	P04626	ERBB2	Y1139	D1144N	1144	Missense	distal	5	no	7.850	7.858	EPSD;PhosphoSitePlus	COSMIC	2.878	Up-regulation
TK_EGFR_ERBB2_Y	P04626	ERBB2	P04626	ERBB2	Y1139	P1143T	1143	Missense	distal	4	no	7.850	7.759	EPSD;PhosphoSitePlus	COSMIC	2.878	Down-regulation
TK_EGFR_ERBB2_Y	P04626	ERBB2	P04626	ERBB2	Y1139	R1146W	1146	Missense	distal	7	no	7.850	7.945	EPSD;PhosphoSitePlus	COSMIC;GDSC;CCLE	2.878	Up-regulation
TK_EGFR_ERBB2_Y	P04626	ERBB2	P04626	ERBB2	Y1139	C1133S	1133	Missense	distal	-6	no	7.850	8.105	EPSD;PhosphoSitePlus	COSMIC	2.878	Up-regulation
TK_EGFR_ERBB2_Y	P04626	ERBB2	P04626	ERBB2	Y1139	D1144H	1144	Missense	distal	5	no	7.850	7.725	EPSD;PhosphoSitePlus	COSMIC;GDSC	2.878	Down-regulation
TK_EGFR_ERBB2_Y	P04626	ERBB2	P04626	ERBB2	Y1196	G1201V	1201	Missense	distal	5	no	6.266	6.286	EPSD;PhosphoSitePlus	COSMIC	2.878	Up-regulation
TK_EGFR_ERBB2_Y	P04626	ERBB2	P04626	ERBB2	Y1196	G1202V	1202	Missense	distal	6	no	6.266	6.331	EPSD;PhosphoSitePlus	COSMIC	2.878	Up-regulation
TK_EGFR_ERBB2_Y	P04626	ERBB2	P04626	ERBB2	Y1196	E1195K	1195	Missense	proximal	-1	no	6.266	5.871	EPSD;PhosphoSitePlus	COSMIC	2.878	Down-regulation
TK_EGFR_ERBB2_Y	P04626	ERBB2	P04626	ERBB2	Y1196	L1197F	1197	Missense	proximal	1	no	6.266	6.245	EPSD;PhosphoSitePlus	COSMIC	2.878	Down-regulation
TK_EGFR_ERBB2_Y	P04626	ERBB2	P04626	ERBB2	Y1196	V1191M	1191	Missense	distal	-5	no	6.266	6.050	EPSD;PhosphoSitePlus	COSMIC	2.878	Down-regulation
TK_EGFR_ERBB2_Y	P04626	ERBB2	P04626	ERBB2	Y1196	Q1200H	1200	Missense	distal	4	no	6.266	6.211	EPSD;PhosphoSitePlus	COSMIC	2.878	Down-regulation
TK_EGFR_ERBB2_Y	P04626	ERBB2	P04626	ERBB2	Y1221	A1216D	1216	Missense	distal	-5	no	7.240	7.237	EPSD;PhosphoSitePlus	COSMIC	2.878	Down-regulation
TK_EGFR_ERBB2_Y	P04626	ERBB2	P04626	ERBB2	Y1221	P1227S	1227	Missense	distal	6	no	7.240	7.293	EPSD;PhosphoSitePlus	COSMIC	2.878	Up-regulation
TK_EGFR_ERBB2_Y	P04626	ERBB2	P04626	ERBB2	Y1222	A1216D	1216	Missense	distal	-6	no	7.251	6.984	PhosphoSitePlus;EPSD	COSMIC	2.878	Down-regulation
TK_EGFR_ERBB2_Y	P04626	ERBB2	P04626	ERBB2	Y1222	E1229Q	1229	Missense	distal	7	no	7.251	7.272	PhosphoSitePlus;EPSD	COSMIC	2.878	Up-regulation
TK_EGFR_ERBB2_Y	P04626	ERBB2	P04626	ERBB2	Y1222	E1229D	1229	Missense	distal	7	no	7.251	7.128	PhosphoSitePlus;EPSD	COSMIC	2.878	Down-regulation
TK_EGFR_ERBB2_Y	P04626	ERBB2	P04626	ERBB2	Y1222	P1227S	1227	Missense	distal	5	no	7.251	7.272	PhosphoSitePlus;EPSD	COSMIC	2.878	Up-regulation
TK_EGFR_ERBB2_Y	P35222	CTNNB1	P04626	ERBB2	Y30	S33L	33	Missense	distal	3	no	2.709	2.910	EPSD	COSMIC;CCLE	2.878	Gain
TK_EGFR_ERBB2_Y	P35222	CTNNB1	P04626	ERBB2	Y30	S29Y	29	Missense	proximal	-1	no	2.709	3.119	EPSD	COSMIC	2.878	Gain
TK_EGFR_ERBB2_Y	P35222	CTNNB1	P04626	ERBB2	Y30	H24Q	24	Missense	distal	-6	no	2.709	2.878	EPSD	COSMIC	2.878	Gain
TK_EGFR_ERBB2_Y	P35222	CTNNB1	P04626	ERBB2	Y30	H24R	24	Missense	distal	-6	no	2.709	2.894	EPSD	COSMIC	2.878	Gain
TK_EGFR_ERBB2_Y	P35222	CTNNB1	P04626	ERBB2	Y30	I35K	35	Missense	distal	5	no	2.709	2.908	EPSD	COSMIC	2.878	Gain
TK_EGFR_ERBB2_Y	P35222	CTNNB1	P04626	ERBB2	Y30	S29T	29	Missense	proximal	-1	no	2.709	3.047	EPSD	COSMIC	2.878	Gain
TK_EGFR_ERBB2_Y	P35222	CTNNB1	P04626	ERBB2	Y654	T653R	653	Missense	proximal	-1	no	6.363	6.146	PhosphoSitePlus	COSMIC	2.878	Down-regulation
TK_EGFR_ERBB2_Y	P35222	CTNNB1	P04626	ERBB2	Y654	A657T	657	Missense	distal	3	no	6.363	6.464	PhosphoSitePlus	COSMIC	2.878	Up-regulation
TK_EGFR_ERBB2_Y	P35222	CTNNB1	P04626	ERBB2	Y654	R647G	647	Missense	distal	-7	no	6.363	6.329	PhosphoSitePlus	COSMIC	2.878	Down-regulation
TK_EGFR_ERBB2_Y	P35222	CTNNB1	P04626	ERBB2	Y654	R661Q	661	Missense	distal	7	no	6.363	6.348	PhosphoSitePlus	COSMIC;CCLE	2.878	Down-regulation
TK_EGFR_ERBB2_Y	P35222	CTNNB1	P04626	ERBB2	Y654	A652V	652	Missense	proximal	-2	no	6.363	5.009	PhosphoSitePlus	COSMIC	2.878	Down-regulation
TK_EGFR_ERBB2_Y	P35222	CTNNB1	P04626	ERBB2	Y654	R661L	661	Missense	distal	7	no	6.363	6.385	PhosphoSitePlus	COSMIC	2.878	Up-regulation
TK_EGFR_ERBB2_Y	P35222	CTNNB1	P04626	ERBB2	Y654	R661P	661	Missense	distal	7	no	6.363	6.300	PhosphoSitePlus	COSMIC	2.878	Down-regulation
TK_EGFR_ERBB2_Y	P35222	CTNNB1	P04626	ERBB2	Y654	V658F	658	Missense	distal	4	no	6.363	6.297	PhosphoSitePlus	COSMIC;GDSC	2.878	Down-regulation
TK_EGFR_ERBB2_Y	P35222	CTNNB1	P04626	ERBB2	Y654	L659S	659	Missense	distal	5	no	6.363	6.561	PhosphoSitePlus	COSMIC	2.878	Up-regulation
TK_EGFR_ERBB2_Y	P35222	CTNNB1	P04626	ERBB2	Y654	V651F	651	Missense	distal	-3	no	6.363	6.181	PhosphoSitePlus	COSMIC	2.878	Down-regulation
TK_EGFR_ERBB2_Y	P35222	CTNNB1	P04626	ERBB2	Y654	A656T	656	Missense	proximal	2	no	6.363	6.161	PhosphoSitePlus	COSMIC	2.878	Down-regulation
TK_EGFR_ERBB2_Y	P35222	CTNNB1	P04626	ERBB2	Y716	R717C	717	Missense	proximal	1	no	2.749	2.903	EPSD	COSMIC	2.878	Gain
TK_EGFR_ERBB2_Y	Q96N67	DOCK7	P04626	ERBB2	Y848	S847L	847	Missense	proximal	-1	no	2.750	3.292	EPSD	COSMIC	2.878	Gain
TK_EGFR_ERBB2_Y	Q96N67	DOCK7	P04626	ERBB2	Y1242	L1243I	1243	Missense	proximal	1	no	3.211	3.107	EPSD	COSMIC	2.878	Down-regulation
TK_EGFR_ERBB2_Y	Q96N67	DOCK7	P04626	ERBB2	Y1242	R1237L	1237	Missense	distal	-5	no	3.211	3.139	EPSD	COSMIC	2.878	Down-regulation
TK_EGFR_ERBB2_Y	Q96N67	DOCK7	P04626	ERBB2	Y1242	I1248V	1248	Missense	distal	6	no	3.211	3.195	EPSD	COSMIC	2.878	Down-regulation
TK_EGFR_ERBB2_Y	Q96N67	DOCK7	P04626	ERBB2	Y1242	R1237G	1237	Missense	distal	-5	no	3.211	3.145	EPSD	COSMIC	2.878	Down-regulation
TK_EGFR_ERBB2_Y	Q96N67	DOCK7	P04626	ERBB2	Y1257	H1263D	1263	Missense	distal	6	no	5.733	5.317	PhosphoSitePlus	COSMIC	2.878	Down-regulation
TK_EGFR_ERBB2_Y	Q96N67	DOCK7	P04626	ERBB2	Y1257	P1254H	1254	Missense	distal	-3	no	5.733	5.230	PhosphoSitePlus	COSMIC	2.878	Down-regulation
TK_EGFR_ERBB2_Y	Q96N67	DOCK7	P04626	ERBB2	Y1257	H1263Q	1263	Missense	distal	6	no	5.733	5.301	PhosphoSitePlus	COSMIC	2.878	Down-regulation
TK_EGFR_ERBB2_Y	P06493	CDK1	P04626	ERBB2	Y15	V18L	18	Missense	distal	3	no	4.825	5.040	PhosphoSitePlus	COSMIC	2.878	Up-regulation
TK_EGFR_ERBB2_Y	P06493	CDK1	P04626	ERBB2	Y15	E12K	12	Missense	distal	-3	no	4.825	4.790	PhosphoSitePlus	COSMIC	2.878	Down-regulation
TK_EGFR_ERBB2_Y	P06493	CDK1	P04626	ERBB2	Y15	Y15C	15	Missense	central	0	yes	4.825	0.000	PhosphoSitePlus	COSMIC	2.878	Loss
TK_EGFR_ERBB2_Y	P00338	LDHA	P04626	ERBB2	Y10	T3I	3	Missense	distal	-7	no	3.820	3.613	PhosphoSitePlus	COSMIC	2.878	Down-regulation
AGC_DMPK_GEK_CDC42BPA_ST	Q5VT25	CDC42BPA	Q5VT25	CDC42BPA	S222	D229N	229	Missense	distal	7	no	5.515	5.286	EPSD	COSMIC	2.124	Down-regulation
AGC_DMPK_GEK_CDC42BPA_ST	Q5VT25	CDC42BPA	Q5VT25	CDC42BPA	S222	D229A	229	Missense	distal	7	no	5.515	5.406	EPSD	COSMIC	2.124	Down-regulation
AGC_DMPK_GEK_CDC42BPA_ST	Q5VT25	CDC42BPA	Q5VT25	CDC42BPA	S234	D229N	229	Missense	distal	-5	no	5.474	5.426	EPSD;PhosphoSitePlus	COSMIC	2.124	Down-regulation
AGC_DMPK_GEK_CDC42BPA_ST	Q5VT25	CDC42BPA	Q5VT25	CDC42BPA	S234	V236I	236	Missense	proximal	2	no	5.474	5.153	EPSD;PhosphoSitePlus	COSMIC	2.124	Down-regulation
AGC_DMPK_GEK_CDC42BPA_ST	Q5VT25	CDC42BPA	Q5VT25	CDC42BPA	S234	D229A	229	Missense	distal	-5	no	5.474	5.436	EPSD;PhosphoSitePlus	COSMIC	2.124	Down-regulation
AGC_DMPK_GEK_CDC42BPA_ST	Q5VT25	CDC42BPA	Q5VT25	CDC42BPA	T240	S245N	245	Missense	distal	5	no	5.481	5.370	EPSD;PhosphoSitePlus	COSMIC	2.124	Down-regulation
AGC_DMPK_GEK_CDC42BPA_ST	Q5VT25	CDC42BPA	Q5VT25	CDC42BPA	T240	V236I	236	Missense	distal	-4	no	5.481	5.501	EPSD;PhosphoSitePlus	COSMIC	2.124	Up-regulation
AGC_DMPK_GEK_CDC42BPA_ST	Q5VT25	CDC42BPA	Q5VT25	CDC42BPA	T240	S245C	245	Missense	distal	5	no	5.481	5.400	EPSD;PhosphoSitePlus	COSMIC	2.124	Down-regulation
AGC_DMPK_GEK_CDC42BPA_ST	Q5VT25	CDC42BPA	Q5VT25	CDC42BPA	S989	R996K	996	Missense	distal	7	no	2.369	2.199	EPSD	COSMIC	2.124	Down-regulation
AGC_DMPK_GEK_CDC42BPA_ST	Q5VT25	CDC42BPA	Q5VT25	CDC42BPA	S989	H991Y	991	Missense	proximal	2	no	2.369	2.358	EPSD	COSMIC	2.124	Down-regulation
AGC_DMPK_GEK_CDC42BPA_ST	Q5VT25	CDC42BPA	Q5VT25	CDC42BPA	T992	R996K	996	Missense	distal	4	no	2.464	2.399	EPSD	COSMIC	2.124	Down-regulation
AGC_DMPK_GEK_CDC42BPA_ST	Q5VT25	CDC42BPA	Q5VT25	CDC42BPA	T992	H991Y	991	Missense	proximal	-1	no	2.464	2.559	EPSD	COSMIC	2.124	Up-regulation
AGC_DMPK_GEK_CDC42BPA_ST	Q5VT25	CDC42BPA	Q5VT25	CDC42BPA	T992	G999R	999	Missense	distal	7	no	2.464	2.348	EPSD	COSMIC	2.124	Down-regulation
AGC_DMPK_GEK_CDC42BPA_ST	Q5VT25	CDC42BPA	Q5VT25	CDC42BPA	T992	G999E	999	Missense	distal	7	no	2.464	2.268	EPSD	COSMIC	2.124	Down-regulation
AGC_DMPK_GEK_CDC42BPA_ST	Q5VT25	CDC42BPA	Q5VT25	CDC42BPA	S1003	R1010C	1010	Missense	distal	7	no	5.520	5.427	EPSD;PhosphoSitePlus	COSMIC	2.124	Down-regulation
AGC_DMPK_GEK_CDC42BPA_ST	Q5VT25	CDC42BPA	Q5VT25	CDC42BPA	S1003	R996K	996	Missense	distal	-7	no	5.520	5.515	EPSD;PhosphoSitePlus	COSMIC	2.124	Down-regulation
AGC_DMPK_GEK_CDC42BPA_ST	Q5VT25	CDC42BPA	Q5VT25	CDC42BPA	S1003	K1009R	1009	Missense	distal	6	no	5.520	5.501	EPSD;PhosphoSitePlus	COSMIC	2.124	Down-regulation
AGC_DMPK_GEK_CDC42BPA_ST	Q5VT25	CDC42BPA	Q5VT25	CDC42BPA	S1003	K1009N	1009	Missense	distal	6	no	5.520	5.501	EPSD;PhosphoSitePlus	COSMIC	2.124	Down-regulation
AGC_DMPK_GEK_CDC42BPA_ST	Q5VT25	CDC42BPA	Q5VT25	CDC42BPA	S1003	G999R	999	Missense	distal	-4	no	5.520	5.819	EPSD;PhosphoSitePlus	COSMIC	2.124	Up-regulation
AGC_DMPK_GEK_CDC42BPA_ST	Q5VT25	CDC42BPA	Q5VT25	CDC42BPA	S1003	G999E	999	Missense	distal	-4	no	5.520	5.559	EPSD;PhosphoSitePlus	COSMIC	2.124	Up-regulation
AGC_DMPK_GEK_CDC42BPA_ST	Q5VT25	CDC42BPA	Q5VT25	CDC42BPA	S1003	G1002C	1002	Missense	proximal	-1	no	5.520	5.409	EPSD;PhosphoSitePlus	COSMIC	2.124	Down-regulation
AGC_DMPK_GEK_CDC42BPA_ST	Q5VT25	CDC42BPA	Q5VT25	CDC42BPA	S1003	G1002A	1002	Missense	proximal	-1	no	5.520	5.467	EPSD;PhosphoSitePlus	COSMIC	2.124	Down-regulation
AGC_DMPK_GEK_CDC42BPA_ST	Q5VT25	CDC42BPA	Q5VT25	CDC42BPA	S1003	G1005D	1005	Missense	proximal	2	no	5.520	5.749	EPSD;PhosphoSitePlus	COSMIC	2.124	Up-regulation
AGC_DMPK_GEK_CDC42BPA_ST	Q5VT25	CDC42BPA	Q5VT25	CDC42BPA	S1173	S1171L	1171	Missense	proximal	-2	no	1.950	2.488	EPSD	COSMIC	2.124	Gain
AGC_DMPK_GEK_CDC42BPA_ST	Q5VT25	CDC42BPA	Q5VT25	CDC42BPA	S1627	E1623Q	1623	Missense	distal	-4	no	2.178	2.450	EPSD	COSMIC	2.124	Up-regulation
AGC_DMPK_GEK_CDC42BPA_ST	Q5VT25	CDC42BPA	Q5VT25	CDC42BPA	S1627	P1622L	1622	Missense	distal	-5	no	2.178	2.283	EPSD	COSMIC	2.124	Up-regulation
AGC_DMPK_GEK_CDC42BPA_ST	Q5VT25	CDC42BPA	Q5VT25	CDC42BPA	S1627	R1621L	1621	Missense	distal	-6	no	2.178	2.102	EPSD	COSMIC	2.124	Loss
AGC_DMPK_GEK_CDC42BPA_ST	Q5VT25	CDC42BPA	Q5VT25	CDC42BPA	S1627	R1626C	1626	Missense	proximal	-1	no	2.178	2.223	EPSD	COSMIC	2.124	Up-regulation
AGC_DMPK_GEK_CDC42BPA_ST	Q5VT25	CDC42BPA	Q5VT25	CDC42BPA	S1627	R1621C	1621	Missense	distal	-6	no	2.178	2.169	EPSD	COSMIC	2.124	Down-regulation
AGC_DMPK_GEK_CDC42BPA_ST	Q5VT25	CDC42BPA	Q5VT25	CDC42BPA	S1627	S1632N	1632	Missense	distal	5	no	2.178	2.067	EPSD	COSMIC	2.124	Loss
AGC_DMPK_GEK_CDC42BPA_ST	Q5VT25	CDC42BPA	Q5VT25	CDC42BPA	S1627	P1622S	1622	Missense	distal	-5	no	2.178	2.100	EPSD	COSMIC	2.124	Loss
AGC_DMPK_GEK_CDC42BPA_ST	Q5VT25	CDC42BPA	Q5VT25	CDC42BPA	S1627	S1620C	1620	Missense	distal	-7	no	2.178	2.248	EPSD	COSMIC	2.124	Up-regulation
AGC_DMPK_GEK_CDC42BPA_ST	Q5VT25	CDC42BPA	Q5VT25	CDC42BPA	S1627	R1626W	1626	Missense	proximal	-1	no	2.178	2.232	EPSD	COSMIC	2.124	Up-regulation
AGC_DMPK_GEK_CDC42BPA_ST	Q5VT25	CDC42BPA	Q5VT25	CDC42BPA	S1627	S1631F	1631	Missense	distal	4	no	2.178	2.214	EPSD	COSMIC	2.124	Up-regulation
AGC_DMPK_GEK_CDC42BPA_ST	Q5VT25	CDC42BPA	Q5VT25	CDC42BPA	S1654	S1656F	1656	Missense	proximal	2	no	3.012	2.965	EPSD	COSMIC;GDSC;CCLE	2.124	Down-regulation
AGC_DMPK_GEK_CDC42BPA_ST	Q5VT25	CDC42BPA	Q5VT25	CDC42BPA	S1654	R1648S	1648	Missense	distal	-6	no	3.012	3.025	EPSD	COSMIC	2.124	Up-regulation
AGC_DMPK_GEK_CDC42BPA_ST	Q5VT25	CDC42BPA	Q5VT25	CDC42BPA	S1654	R1659W	1659	Missense	distal	5	no	3.012	2.969	EPSD	COSMIC	2.124	Down-regulation
AGC_DMPK_GEK_CDC42BPA_ST	Q5VT25	CDC42BPA	Q5VT25	CDC42BPA	S1654	F1650I	1650	Missense	distal	-4	no	3.012	3.109	EPSD	COSMIC	2.124	Up-regulation
AGC_DMPK_GEK_CDC42BPA_ST	Q5VT25	CDC42BPA	Q5VT25	CDC42BPA	S1654	G1653E	1653	Missense	proximal	-1	no	3.012	2.881	EPSD	COSMIC	2.124	Down-regulation
AGC_DMPK_GEK_CDC42BPA_ST	Q5VT25	CDC42BPA	Q5VT25	CDC42BPA	S1666	S1669F	1669	Missense	distal	3	no	1.992	2.192	EPSD	COSMIC	2.124	Gain
AGC_DMPK_GEK_CDC42BPA_ST	Q5VT25	CDC42BPA	Q5VT25	CDC42BPA	S1666	S1664F	1664	Missense	proximal	-2	no	1.992	2.727	EPSD	COSMIC	2.124	Gain
AGC_DMPK_GEK_CDC42BPA_ST	Q5VT25	CDC42BPA	Q5VT25	CDC42BPA	S1697	H1696N	1696	Missense	proximal	-1	no	2.168	2.157	EPSD	COSMIC	2.124	Down-regulation
AGC_DMPK_GEK_CDC42BPA_ST	Q5VT25	CDC42BPA	Q5VT25	CDC42BPA	S1729	D1731E	1731	Missense	proximal	2	no	2.265	2.243	EPSD	COSMIC	2.124	Down-regulation
AGC_DMPK_GEK_CDC42BPA_ST	Q5VT25	CDC42BPA	Q5VT25	CDC42BPA	S1729	R1727C	1727	Missense	proximal	-2	no	2.265	1.947	EPSD	COSMIC	2.124	Loss
AGC_DMPK_GEK_CDC42BPA_ST	P24844	MYL9	Q5VT25	CDC42BPA	S20	N21T	21	Missense	proximal	1	no	5.235	4.793	PhosphoSitePlus	COSMIC	2.124	Down-regulation
AGC_DMPK_GEK_CDC42BPA_ST	P24844	MYL9	Q5VT25	CDC42BPA	S20	P15S	15	Missense	distal	-5	no	5.235	5.157	PhosphoSitePlus	COSMIC	2.124	Down-regulation
AGC_DMPK_GEK_CDC42BPA_ST	P24844	MYL9	Q5VT25	CDC42BPA	S20	R14Q	14	Missense	distal	-6	no	5.235	5.237	PhosphoSitePlus	COSMIC	2.124	Up-regulation
AGC_DMPK_GEK_CDC42BPA_ST	P24844	MYL9	Q5VT25	CDC42BPA	T97	D101N	101	Missense	distal	4	no	2.207	2.190	EPSD	COSMIC	2.124	Down-regulation
AGC_DMPK_GEK_CDC42BPA_ST	P24844	MYL9	Q5VT25	CDC42BPA	T97	D98N	98	Missense	proximal	1	no	2.207	2.652	EPSD	COSMIC	2.124	Up-regulation
AGC_DMPK_GEK_CDC42BPA_ST	P24844	MYL9	Q5VT25	CDC42BPA	T135	M130I	130	Missense	distal	-5	no	2.231	2.372	EPSD	COSMIC	2.124	Up-regulation
STE_STE20_FRAY_OXSR1_ST	Q13621	SLC12A1	O95747	OXSR1	S91	H87Y	87	Missense	distal	-4	no	24.831	24.730	EPSD	COSMIC	17.710	Down-regulation
STE_STE20_FRAY_OXSR1_ST	Q13621	SLC12A1	O95747	OXSR1	S91	Y89H	89	Missense	proximal	-2	no	24.831	25.315	EPSD	COSMIC	17.710	Up-regulation
STE_STE20_FRAY_OXSR1_ST	Q13621	SLC12A1	O95747	OXSR1	T95	Y89H	89	Missense	distal	-6	no	50.566	50.709	EPSD;PhosphoSitePlus	COSMIC	17.710	Up-regulation
STE_STE20_FRAY_OXSR1_ST	Q13621	SLC12A1	O95747	OXSR1	T95	F101V	101	Missense	distal	6	no	50.566	51.373	EPSD;PhosphoSitePlus	COSMIC	17.710	Up-regulation
STE_STE20_FRAY_OXSR1_ST	Q13621	SLC12A1	O95747	OXSR1	T100	F101V	101	Missense	proximal	1	no	44.600	39.028	EPSD;PhosphoSitePlus	COSMIC	17.710	Down-regulation
STE_STE20_FRAY_OXSR1_ST	Q13621	SLC12A1	O95747	OXSR1	T105	I112R	112	Missense	distal	7	no	50.424	50.221	PhosphoSitePlus;EPSD	COSMIC	17.710	Down-regulation
STE_STE20_FRAY_OXSR1_ST	Q13621	SLC12A1	O95747	OXSR1	T105	F101V	101	Missense	distal	-4	no	50.424	47.354	PhosphoSitePlus;EPSD	COSMIC	17.710	Down-regulation
STE_STE20_FRAY_OXSR1_ST	Q13621	SLC12A1	O95747	OXSR1	T118	I112R	112	Missense	distal	-6	no	46.996	47.860	EPSD;PhosphoSitePlus	COSMIC	17.710	Up-regulation
STE_STE20_FRAY_OXSR1_ST	Q13621	SLC12A1	O95747	OXSR1	T118	G119S	119	Missense	proximal	1	no	46.996	47.619	EPSD;PhosphoSitePlus	COSMIC	17.710	Up-regulation
STE_STE20_FRAY_OXSR1_ST	Q13621	SLC12A1	O95747	OXSR1	S120	G119S	119	Missense	proximal	-1	no	46.596	47.378	EPSD;PhosphoSitePlus	COSMIC	17.710	Up-regulation
STE_STE20_FRAY_OXSR1_ST	Q13621	SLC12A1	O95747	OXSR1	S122	G119S	119	Missense	distal	-3	no	19.343	18.741	EPSD	COSMIC	17.710	Down-regulation
STE_STE20_FRAY_OXSR1_ST	Q13621	SLC12A1	O95747	OXSR1	T882	M886V	886	Missense	distal	4	no	26.055	26.225	EPSD	COSMIC	17.710	Up-regulation
STE_STE20_FRAY_OXSR1_ST	Q13621	SLC12A1	O95747	OXSR1	T882	K876E	876	Missense	distal	-6	no	26.055	25.775	EPSD	COSMIC	17.710	Down-regulation
STE_STE20_FRAY_OXSR1_ST	Q13621	SLC12A1	O95747	OXSR1	T882	K875N	875	Missense	distal	-7	no	26.055	26.058	EPSD	COSMIC	17.710	Up-regulation
STE_STE20_FRAY_OXSR1_ST	Q13621	SLC12A1	O95747	OXSR1	S885	M886V	886	Missense	proximal	1	no	18.307	14.494	EPSD	COSMIC	17.710	Loss
STE_STE20_FRAY_OXSR1_ST	P55011	SLC12A2	O95747	OXSR1	T203	T207I	207	Missense	distal	4	no	54.158	54.573	EPSD;PhosphoSitePlus	COSMIC;GDSC;CCLE	17.710	Up-regulation
STE_STE20_FRAY_OXSR1_ST	P55011	SLC12A2	O95747	OXSR1	T207	T207I	207	Missense	central	0	yes	48.398	0.000	PhosphoSitePlus;EPSD	COSMIC;GDSC;CCLE	17.710	Loss
STE_STE20_FRAY_OXSR1_ST	P55011	SLC12A2	O95747	OXSR1	T212	T207I	207	Missense	distal	-5	no	50.448	42.475	EPSD;PhosphoSitePlus	COSMIC;GDSC;CCLE	17.710	Down-regulation
STE_STE20_FRAY_OXSR1_ST	P55011	SLC12A2	O95747	OXSR1	T212	T217I	217	Missense	distal	5	no	50.448	50.804	EPSD;PhosphoSitePlus	COSMIC	17.710	Up-regulation
STE_STE20_FRAY_OXSR1_ST	P55011	SLC12A2	O95747	OXSR1	T217	T217I	217	Missense	central	0	yes	47.746	0.000	EPSD;PhosphoSitePlus	COSMIC	17.710	Loss
STE_STE20_FRAY_OXSR1_ST	P55017	SLC12A3	O95747	OXSR1	T46	H41P	41	Missense	distal	-5	no	45.760	40.137	EPSD;PhosphoSitePlus	COSMIC	17.710	Down-regulation
STE_STE20_FRAY_OXSR1_ST	P55017	SLC12A3	O95747	OXSR1	T46	C52R	52	Missense	distal	6	no	45.760	45.269	EPSD;PhosphoSitePlus	COSMIC	17.710	Down-regulation
STE_STE20_FRAY_OXSR1_ST	P55017	SLC12A3	O95747	OXSR1	T50	C52R	52	Missense	proximal	2	no	27.861	28.195	EPSD	COSMIC	17.710	Up-regulation
STE_STE20_FRAY_OXSR1_ST	P55017	SLC12A3	O95747	OXSR1	T50	R54H	54	Missense	distal	4	no	27.861	27.894	EPSD	COSMIC;GDSC;CCLE	17.710	Up-regulation
STE_STE20_FRAY_OXSR1_ST	P55017	SLC12A3	O95747	OXSR1	T55	C52R	52	Missense	distal	-3	no	45.147	42.622	EPSD;PhosphoSitePlus	COSMIC	17.710	Down-regulation
STE_STE20_FRAY_OXSR1_ST	P55017	SLC12A3	O95747	OXSR1	T55	R54H	54	Missense	proximal	-1	no	45.147	46.396	EPSD;PhosphoSitePlus	COSMIC;GDSC;CCLE	17.710	Up-regulation
STE_STE20_FRAY_OXSR1_ST	P55017	SLC12A3	O95747	OXSR1	T60	R54H	54	Missense	distal	-6	no	53.253	53.612	PhosphoSitePlus;EPSD	COSMIC;GDSC;CCLE	17.710	Up-regulation
STE_STE20_FRAY_OXSR1_ST	P55017	SLC12A3	O95747	OXSR1	T74	K81R	81	Missense	distal	7	no	25.815	25.634	EPSD	COSMIC	17.710	Down-regulation
STE_STE20_FRAY_OXSR1_ST	P55017	SLC12A3	O95747	OXSR1	T85	V82I	82	Missense	distal	-3	no	14.801	19.740	EPSD	COSMIC	17.710	Gain
TK_Src_SrcA_SRC_Y	Q14790	CASP8	P12931	SRC	Y226	L222P	222	Missense	distal	-4	no	20.696	21.331	EPSD	COSMIC	20.673	Up-regulation
TK_Src_SrcA_SRC_Y	Q14790	CASP8	P12931	SRC	Y226	R233Q	233	Missense	distal	7	no	20.696	20.654	EPSD	COSMIC	20.673	Loss
TK_Src_SrcA_SRC_Y	Q14790	CASP8	P12931	SRC	Y226	R233L	233	Missense	distal	7	no	20.696	20.672	EPSD	COSMIC	20.673	Loss
TK_Src_SrcA_SRC_Y	Q14790	CASP8	P12931	SRC	Y226	R233W	233	Missense	distal	7	no	20.696	20.793	EPSD	COSMIC;CCLE	20.673	Up-regulation
TK_Src_SrcA_SRC_Y	Q14790	CASP8	P12931	SRC	Y226	M228I	228	Missense	proximal	2	no	20.696	19.767	EPSD	COSMIC;CCLE	20.673	Loss
TK_Src_SrcA_SRC_Y	Q14790	CASP8	P12931	SRC	Y226	Y226C	226	Missense	central	0	yes	20.696	0.000	EPSD	COSMIC	20.673	Loss
TK_Src_SrcA_SRC_Y	Q14790	CASP8	P12931	SRC	Y226	Y226F	226	Missense	central	0	yes	20.696	0.000	EPSD	COSMIC	20.673	Loss
TK_Src_SrcA_SRC_Y	Q14790	CASP8	P12931	SRC	Y226	M228T	228	Missense	proximal	2	no	20.696	20.844	EPSD	COSMIC	20.673	Up-regulation
TK_Src_SrcA_SRC_Y	Q14790	CASP8	P12931	SRC	Y226	P232L	232	Missense	distal	6	no	20.696	20.712	EPSD	COSMIC	20.673	Up-regulation
TK_Src_SrcA_SRC_Y	Q14790	CASP8	P12931	SRC	Y226	S230N	230	Missense	distal	4	no	20.696	20.728	EPSD	COSMIC	20.673	Up-regulation
TK_Src_SrcA_SRC_Y	Q14790	CASP8	P12931	SRC	Y226	P232H	232	Missense	distal	6	no	20.696	20.704	EPSD	COSMIC;CCLE	20.673	Up-regulation
TK_Src_SrcA_SRC_Y	Q14790	CASP8	P12931	SRC	Y226	P232R	232	Missense	distal	6	no	20.696	20.675	EPSD	COSMIC	20.673	Down-regulation
TK_Src_SrcA_SRC_Y	Q14790	CASP8	P12931	SRC	Y334	I333M	333	Missense	proximal	-1	no	21.016	19.784	EPSD	COSMIC	20.673	Loss
TK_Src_SrcA_SRC_Y	Q14790	CASP8	P12931	SRC	Y334	S338F	338	Missense	distal	4	no	21.016	21.005	EPSD	COSMIC;CCLE	20.673	Down-regulation
TK_Src_SrcA_SRC_Y	Q14790	CASP8	P12931	SRC	Y334	A331T	331	Missense	distal	-3	no	21.016	21.210	EPSD	COSMIC	20.673	Up-regulation
TK_Src_SrcA_SRC_Y	Q14790	CASP8	P12931	SRC	Y334	Q339R	339	Missense	distal	5	no	21.016	20.991	EPSD	COSMIC	20.673	Down-regulation
TK_Src_SrcA_SRC_Y	Q14790	CASP8	P12931	SRC	Y334	S338C	338	Missense	distal	4	no	21.016	20.991	EPSD	COSMIC	20.673	Down-regulation
TK_Src_SrcA_SRC_Y	Q14790	CASP8	P12931	SRC	Y334	G328V	328	Missense	distal	-6	no	21.016	20.909	EPSD	COSMIC	20.673	Down-regulation
TK_Src_SrcA_SRC_Y	Q14790	CASP8	P12931	SRC	Y334	I333S	333	Missense	proximal	-1	no	21.016	19.942	EPSD	COSMIC	20.673	Loss
TK_Src_SrcA_SRC_Y	Q14790	CASP8	P12931	SRC	Y334	E335K	335	Missense	proximal	1	no	21.016	18.621	EPSD	COSMIC	20.673	Loss
TK_Src_SrcA_SRC_Y	Q14790	CASP8	P12931	SRC	Y334	Y334C	334	Missense	central	0	yes	21.016	0.000	EPSD	COSMIC	20.673	Loss
TK_Src_SrcA_SRC_Y	Q14790	CASP8	P12931	SRC	Y334	E335V	335	Missense	proximal	1	no	21.016	19.134	EPSD	COSMIC	20.673	Loss
TK_Src_SrcA_SRC_Y	Q14790	CASP8	P12931	SRC	Y334	G328R	328	Missense	distal	-6	no	21.016	21.018	EPSD	COSMIC	20.673	Up-regulation
TK_Src_SrcA_SRC_Y	Q14790	CASP8	P12931	SRC	Y334	G328E	328	Missense	distal	-6	no	21.016	21.245	EPSD	COSMIC	20.673	Up-regulation
TK_Src_SrcA_SRC_Y	Q14790	CASP8	P12931	SRC	Y380	P379L	379	Missense	proximal	-1	no	21.749	21.735	EPSD;PhosphoSitePlus	COSMIC	20.673	Down-regulation
TK_Src_SrcA_SRC_Y	Q14790	CASP8	P12931	SRC	Y380	P379S	379	Missense	proximal	-1	no	21.749	21.397	EPSD;PhosphoSitePlus	COSMIC	20.673	Down-regulation
TK_Src_SrcA_SRC_Y	Q14790	CASP8	P12931	SRC	Y380	L385P	385	Missense	distal	5	no	21.749	21.734	EPSD;PhosphoSitePlus	COSMIC	20.673	Down-regulation
TK_Src_SrcA_SRC_Y	Q14790	CASP8	P12931	SRC	Y380	P379Q	379	Missense	proximal	-1	no	21.749	21.915	EPSD;PhosphoSitePlus	COSMIC	20.673	Up-regulation
TK_Src_SrcA_SRC_Y	Q14790	CASP8	P12931	SRC	Y380	P379T	379	Missense	proximal	-1	no	21.749	21.491	EPSD;PhosphoSitePlus	COSMIC	20.673	Down-regulation
TK_Src_SrcA_SRC_Y	Q14790	CASP8	P12931	SRC	Y380	S375L	375	Missense	distal	-5	no	21.749	21.490	EPSD;PhosphoSitePlus	COSMIC	20.673	Down-regulation
TK_Src_SrcA_SRC_Y	Q14790	CASP8	P12931	SRC	Y380	D384N	384	Missense	distal	4	no	21.749	21.765	EPSD;PhosphoSitePlus	COSMIC	20.673	Up-regulation
TK_Src_SrcA_SRC_Y	Q14790	CASP8	P12931	SRC	Y380	E376V	376	Missense	distal	-4	no	21.749	20.499	EPSD;PhosphoSitePlus	COSMIC	20.673	Loss
TK_Src_SrcA_SRC_Y	Q14790	CASP8	P12931	SRC	Y380	S386L	386	Missense	distal	6	no	21.749	21.780	EPSD;PhosphoSitePlus	COSMIC	20.673	Up-regulation
TK_Src_SrcA_SRC_Y	P60484	PTEN	P12931	SRC	Y27	T26I	26	Missense	proximal	-1	no	19.914	20.893	EPSD	COSMIC	20.673	Gain
TK_Src_SrcA_SRC_Y	P60484	PTEN	P12931	SRC	Y46	I50N	50	Missense	distal	4	no	22.622	22.671	EPSD;PhosphoSitePlus	COSMIC	20.673	Up-regulation
TK_Src_SrcA_SRC_Y	P60484	PTEN	P12931	SRC	Y46	V45A	45	Missense	proximal	-1	no	22.622	21.285	EPSD;PhosphoSitePlus	COSMIC	20.673	Down-regulation
TK_Src_SrcA_SRC_Y	P60484	PTEN	P12931	SRC	Y46	A39T	39	Missense	distal	-7	no	22.622	23.042	EPSD;PhosphoSitePlus	COSMIC	20.673	Up-regulation
TK_Src_SrcA_SRC_Y	P60484	PTEN	P12931	SRC	Y46	V53G	53	Missense	distal	7	no	22.622	22.587	EPSD;PhosphoSitePlus	COSMIC	20.673	Down-regulation
TK_Src_SrcA_SRC_Y	P60484	PTEN	P12931	SRC	Y46	Y46C	46	Missense	central	0	yes	22.622	0.000	EPSD;PhosphoSitePlus	COSMIC;GDSC;CCLE	20.673	Loss
TK_Src_SrcA_SRC_Y	P60484	PTEN	P12931	SRC	Y46	L42R	42	Missense	distal	-4	no	22.622	23.579	EPSD;PhosphoSitePlus	COSMIC;GDSC;CCLE	20.673	Up-regulation
TK_Src_SrcA_SRC_Y	P60484	PTEN	P12931	SRC	Y46	N49I	49	Missense	distal	3	no	22.622	22.236	EPSD;PhosphoSitePlus	COSMIC	20.673	Down-regulation
TK_Src_SrcA_SRC_Y	P60484	PTEN	P12931	SRC	Y46	V53A	53	Missense	distal	7	no	22.622	22.546	EPSD;PhosphoSitePlus	COSMIC	20.673	Down-regulation
TK_Src_SrcA_SRC_Y	P60484	PTEN	P12931	SRC	Y46	R47G	47	Missense	proximal	1	no	22.622	23.615	EPSD;PhosphoSitePlus	COSMIC;GDSC;CCLE	20.673	Up-regulation
TK_Src_SrcA_SRC_Y	P60484	PTEN	P12931	SRC	Y46	A39E	39	Missense	distal	-7	no	22.622	23.023	EPSD;PhosphoSitePlus	COSMIC	20.673	Up-regulation
TK_Src_SrcA_SRC_Y	P60484	PTEN	P12931	SRC	Y46	D52N	52	Missense	distal	6	no	22.622	22.626	EPSD;PhosphoSitePlus	COSMIC	20.673	Up-regulation
TK_Src_SrcA_SRC_Y	P60484	PTEN	P12931	SRC	Y46	D52G	52	Missense	distal	6	no	22.622	22.663	EPSD;PhosphoSitePlus	COSMIC	20.673	Up-regulation
TK_Src_SrcA_SRC_Y	P60484	PTEN	P12931	SRC	Y46	L42F	42	Missense	distal	-4	no	22.622	22.391	EPSD;PhosphoSitePlus	COSMIC	20.673	Down-regulation
TK_Src_SrcA_SRC_Y	P60484	PTEN	P12931	SRC	Y46	N48D	48	Missense	proximal	2	no	22.622	22.409	EPSD;PhosphoSitePlus	COSMIC	20.673	Down-regulation
TK_Src_SrcA_SRC_Y	P60484	PTEN	P12931	SRC	Y46	R47S	47	Missense	proximal	1	no	22.622	23.501	EPSD;PhosphoSitePlus	COSMIC	20.673	Up-regulation
TK_Src_SrcA_SRC_Y	P60484	PTEN	P12931	SRC	Y46	V45I	45	Missense	proximal	-1	no	22.622	22.248	EPSD;PhosphoSitePlus	COSMIC	20.673	Down-regulation
TK_Src_SrcA_SRC_Y	P60484	PTEN	P12931	SRC	Y46	R41K	41	Missense	distal	-5	no	22.622	22.314	EPSD;PhosphoSitePlus	COSMIC	20.673	Down-regulation
TK_Src_SrcA_SRC_Y	P60484	PTEN	P12931	SRC	Y46	L42H	42	Missense	distal	-4	no	22.622	23.096	EPSD;PhosphoSitePlus	COSMIC	20.673	Up-regulation
TK_Src_SrcA_SRC_Y	P60484	PTEN	P12931	SRC	Y155	L152Q	152	Missense	distal	-3	no	18.927	20.738	PhosphoSitePlus;EPSD	COSMIC	20.673	Gain
TK_Src_SrcA_SRC_Y	P60484	PTEN	P12931	SRC	Y155	F154V	154	Missense	proximal	-1	no	18.927	20.896	PhosphoSitePlus;EPSD	COSMIC	20.673	Gain
TK_Src_SrcA_SRC_Y	P60484	PTEN	P12931	SRC	Y176	L181Q	181	Missense	distal	5	no	21.281	21.138	EPSD	COSMIC	20.673	Down-regulation
TK_Src_SrcA_SRC_Y	P60484	PTEN	P12931	SRC	Y176	Y176F	176	Missense	central	0	yes	21.281	0.000	EPSD	COSMIC	20.673	Loss
TK_Src_SrcA_SRC_Y	P60484	PTEN	P12931	SRC	Y176	Y174D	174	Missense	proximal	-2	no	21.281	22.730	EPSD	COSMIC	20.673	Up-regulation
TK_Src_SrcA_SRC_Y	P60484	PTEN	P12931	SRC	Y176	Y174N	174	Missense	proximal	-2	no	21.281	22.450	EPSD	COSMIC	20.673	Up-regulation
TK_Src_SrcA_SRC_Y	P60484	PTEN	P12931	SRC	Y176	R172W	172	Missense	distal	-4	no	21.281	19.908	EPSD	COSMIC	20.673	Loss
TK_Src_SrcA_SRC_Y	P60484	PTEN	P12931	SRC	Y176	R173P	173	Missense	distal	-3	no	21.281	21.236	EPSD	COSMIC;GDSC;CCLE	20.673	Down-regulation
TK_Src_SrcA_SRC_Y	P60484	PTEN	P12931	SRC	Y176	L182F	182	Missense	distal	6	no	21.281	21.280	EPSD	COSMIC	20.673	Down-regulation
TK_Src_SrcA_SRC_Y	P60484	PTEN	P12931	SRC	Y176	P169S	169	Missense	distal	-7	no	21.281	21.401	EPSD	COSMIC	20.673	Up-regulation
TK_Src_SrcA_SRC_Y	P60484	PTEN	P12931	SRC	Y176	V175M	175	Missense	proximal	-1	no	21.281	19.675	EPSD	COSMIC	20.673	Loss
TK_Src_SrcA_SRC_Y	P60484	PTEN	P12931	SRC	Y176	Y178H	178	Missense	proximal	2	no	21.281	20.738	EPSD	COSMIC	20.673	Down-regulation
TK_Src_SrcA_SRC_Y	P60484	PTEN	P12931	SRC	Y176	L182V	182	Missense	distal	6	no	21.281	21.263	EPSD	COSMIC	20.673	Down-regulation
TK_Src_SrcA_SRC_Y	P60484	PTEN	P12931	SRC	Y176	Y177H	177	Missense	proximal	1	no	21.281	20.234	EPSD	COSMIC	20.673	Loss
TK_Src_SrcA_SRC_Y	P60484	PTEN	P12931	SRC	Y176	Q171P	171	Missense	distal	-5	no	21.281	21.421	EPSD	COSMIC	20.673	Up-regulation
TK_Src_SrcA_SRC_Y	P60484	PTEN	P12931	SRC	Y176	P169H	169	Missense	distal	-7	no	21.281	21.354	EPSD	COSMIC	20.673	Up-regulation
TK_Src_SrcA_SRC_Y	P60484	PTEN	P12931	SRC	Y176	K183N	183	Missense	distal	7	no	21.281	21.236	EPSD	COSMIC	20.673	Down-regulation
TK_Src_SrcA_SRC_Y	P60484	PTEN	P12931	SRC	Y176	P169L	169	Missense	distal	-7	no	21.281	21.165	EPSD	COSMIC	20.673	Down-regulation
TK_Src_SrcA_SRC_Y	P60484	PTEN	P12931	SRC	Y176	S179I	179	Missense	distal	3	no	21.281	21.834	EPSD	COSMIC	20.673	Up-regulation
TK_Src_SrcA_SRC_Y	P60484	PTEN	P12931	SRC	Y176	Y176C	176	Missense	central	0	yes	21.281	0.000	EPSD	COSMIC	20.673	Loss
TK_Src_SrcA_SRC_Y	P60484	PTEN	P12931	SRC	Y176	Y178D	178	Missense	proximal	2	no	21.281	21.261	EPSD	COSMIC	20.673	Down-regulation
TK_Src_SrcA_SRC_Y	P60484	PTEN	P12931	SRC	Y176	V175A	175	Missense	proximal	-1	no	21.281	19.944	EPSD	COSMIC	20.673	Loss
TK_Src_SrcA_SRC_Y	P60484	PTEN	P12931	SRC	Y176	Y174C	174	Missense	proximal	-2	no	21.281	20.587	EPSD	COSMIC	20.673	Loss
TK_Src_SrcA_SRC_Y	P60484	PTEN	P12931	SRC	Y176	Y178F	178	Missense	proximal	2	no	21.281	20.301	EPSD	COSMIC	20.673	Loss
TK_Src_SrcA_SRC_Y	P60484	PTEN	P12931	SRC	Y176	Q171H	171	Missense	distal	-5	no	21.281	21.649	EPSD	COSMIC	20.673	Up-regulation
TK_Src_SrcA_SRC_Y	P60484	PTEN	P12931	SRC	Y176	R173S	173	Missense	distal	-3	no	21.281	22.354	EPSD	COSMIC	20.673	Up-regulation
TK_Src_SrcA_SRC_Y	P60484	PTEN	P12931	SRC	Y176	L181R	181	Missense	distal	5	no	21.281	21.113	EPSD	COSMIC	20.673	Down-regulation
TK_Src_SrcA_SRC_Y	P60484	PTEN	P12931	SRC	Y176	Y178N	178	Missense	proximal	2	no	21.281	21.474	EPSD	COSMIC	20.673	Up-regulation
TK_Src_SrcA_SRC_Y	P60484	PTEN	P12931	SRC	Y176	Y174H	174	Missense	proximal	-2	no	21.281	21.949	EPSD	COSMIC	20.673	Up-regulation
TK_Src_SrcA_SRC_Y	P60484	PTEN	P12931	SRC	Y177	L181Q	181	Missense	distal	4	no	21.132	21.120	EPSD	COSMIC	20.673	Down-regulation
TK_Src_SrcA_SRC_Y	P60484	PTEN	P12931	SRC	Y177	Y176F	176	Missense	proximal	-1	no	21.132	19.434	EPSD	COSMIC	20.673	Loss
TK_Src_SrcA_SRC_Y	P60484	PTEN	P12931	SRC	Y177	Y174D	174	Missense	distal	-3	no	21.132	22.521	EPSD	COSMIC	20.673	Up-regulation
TK_Src_SrcA_SRC_Y	P60484	PTEN	P12931	SRC	Y177	Y174N	174	Missense	distal	-3	no	21.132	22.013	EPSD	COSMIC	20.673	Up-regulation
TK_Src_SrcA_SRC_Y	P60484	PTEN	P12931	SRC	Y177	R172W	172	Missense	distal	-5	no	21.132	20.466	EPSD	COSMIC	20.673	Loss
TK_Src_SrcA_SRC_Y	P60484	PTEN	P12931	SRC	Y177	R173P	173	Missense	distal	-4	no	21.132	20.809	EPSD	COSMIC;GDSC;CCLE	20.673	Down-regulation
TK_Src_SrcA_SRC_Y	P60484	PTEN	P12931	SRC	Y177	L182F	182	Missense	distal	5	no	21.132	21.190	EPSD	COSMIC	20.673	Up-regulation
TK_Src_SrcA_SRC_Y	P60484	PTEN	P12931	SRC	Y177	V175M	175	Missense	proximal	-2	no	21.132	20.461	EPSD	COSMIC	20.673	Loss
TK_Src_SrcA_SRC_Y	P60484	PTEN	P12931	SRC	Y177	N184I	184	Missense	distal	7	no	21.132	21.205	EPSD	COSMIC	20.673	Up-regulation
TK_Src_SrcA_SRC_Y	P60484	PTEN	P12931	SRC	Y177	Y178H	178	Missense	proximal	1	no	21.132	20.086	EPSD	COSMIC	20.673	Loss
TK_Src_SrcA_SRC_Y	P60484	PTEN	P12931	SRC	Y177	L182V	182	Missense	distal	5	no	21.132	21.037	EPSD	COSMIC	20.673	Down-regulation
TK_Src_SrcA_SRC_Y	P60484	PTEN	P12931	SRC	Y177	Y177H	177	Missense	central	0	yes	21.132	0.000	EPSD	COSMIC	20.673	Loss
TK_Src_SrcA_SRC_Y	P60484	PTEN	P12931	SRC	Y177	Q171P	171	Missense	distal	-6	no	21.132	21.121	EPSD	COSMIC	20.673	Down-regulation
TK_Src_SrcA_SRC_Y	P60484	PTEN	P12931	SRC	Y177	K183N	183	Missense	distal	6	no	21.132	21.088	EPSD	COSMIC	20.673	Down-regulation
TK_Src_SrcA_SRC_Y	P60484	PTEN	P12931	SRC	Y177	S179I	179	Missense	proximal	2	no	21.132	19.796	EPSD	COSMIC	20.673	Loss
TK_Src_SrcA_SRC_Y	P60484	PTEN	P12931	SRC	Y177	Y176C	176	Missense	proximal	-1	no	21.132	20.063	EPSD	COSMIC	20.673	Loss
TK_Src_SrcA_SRC_Y	P60484	PTEN	P12931	SRC	Y177	Y178D	178	Missense	proximal	1	no	21.132	21.531	EPSD	COSMIC	20.673	Up-regulation
TK_Src_SrcA_SRC_Y	P60484	PTEN	P12931	SRC	Y177	V175A	175	Missense	proximal	-2	no	21.132	21.430	EPSD	COSMIC	20.673	Up-regulation
TK_Src_SrcA_SRC_Y	P60484	PTEN	P12931	SRC	Y177	Y174C	174	Missense	distal	-3	no	21.132	19.331	EPSD	COSMIC	20.673	Loss
TK_Src_SrcA_SRC_Y	P60484	PTEN	P12931	SRC	Y177	Y178F	178	Missense	proximal	1	no	21.132	19.161	EPSD	COSMIC	20.673	Loss
TK_Src_SrcA_SRC_Y	P60484	PTEN	P12931	SRC	Y177	Q171H	171	Missense	distal	-6	no	21.132	20.997	EPSD	COSMIC	20.673	Down-regulation
TK_Src_SrcA_SRC_Y	P60484	PTEN	P12931	SRC	Y177	R173S	173	Missense	distal	-4	no	21.132	20.862	EPSD	COSMIC	20.673	Down-regulation
TK_Src_SrcA_SRC_Y	P60484	PTEN	P12931	SRC	Y177	L181R	181	Missense	distal	4	no	21.132	21.099	EPSD	COSMIC	20.673	Down-regulation
TK_Src_SrcA_SRC_Y	P60484	PTEN	P12931	SRC	Y177	Y178N	178	Missense	proximal	1	no	21.132	20.139	EPSD	COSMIC	20.673	Loss
TK_Src_SrcA_SRC_Y	P60484	PTEN	P12931	SRC	Y177	Y174H	174	Missense	distal	-3	no	21.132	20.944	EPSD	COSMIC	20.673	Down-regulation
TK_Src_SrcA_SRC_Y	P60484	PTEN	P12931	SRC	Y178	Y174D	174	Missense	distal	-4	no	20.648	21.642	EPSD	COSMIC	20.673	Gain
TK_Src_SrcA_SRC_Y	P60484	PTEN	P12931	SRC	Y178	Y174N	174	Missense	distal	-4	no	20.648	21.110	EPSD	COSMIC	20.673	Gain
TK_Src_SrcA_SRC_Y	P60484	PTEN	P12931	SRC	Y178	N184I	184	Missense	distal	6	no	20.648	20.686	EPSD	COSMIC	20.673	Gain
TK_Src_SrcA_SRC_Y	P60484	PTEN	P12931	SRC	Y178	V175A	175	Missense	distal	-3	no	20.648	21.200	EPSD	COSMIC	20.673	Gain
TK_Src_SrcA_SRC_Y	P60484	PTEN	P12931	SRC	Y178	R173S	173	Missense	distal	-5	no	20.648	20.732	EPSD	COSMIC	20.673	Gain
TK_Src_SrcA_SRC_Y	P60484	PTEN	P12931	SRC	Y240	R234Q	234	Missense	distal	-6	no	21.485	21.587	EPSD;PhosphoSitePlus	COSMIC	20.673	Up-regulation
TK_Src_SrcA_SRC_Y	P60484	PTEN	P12931	SRC	Y240	D236E	236	Missense	distal	-4	no	21.485	21.259	EPSD;PhosphoSitePlus	COSMIC	20.673	Down-regulation
TK_Src_SrcA_SRC_Y	P60484	PTEN	P12931	SRC	Y240	F241V	241	Missense	proximal	1	no	21.485	22.579	EPSD;PhosphoSitePlus	COSMIC	20.673	Up-regulation
TK_Src_SrcA_SRC_Y	P60484	PTEN	P12931	SRC	Y240	F238L	238	Missense	proximal	-2	no	21.485	21.721	EPSD;PhosphoSitePlus	COSMIC	20.673	Up-regulation
TK_Src_SrcA_SRC_Y	P60484	PTEN	P12931	SRC	Y240	E242K	242	Missense	proximal	2	no	21.485	20.315	EPSD;PhosphoSitePlus	COSMIC	20.673	Loss
TK_Src_SrcA_SRC_Y	P60484	PTEN	P12931	SRC	Y240	R233G	233	Missense	distal	-7	no	21.485	20.864	EPSD;PhosphoSitePlus	COSMIC;CCLE	20.673	Down-regulation
TK_Src_SrcA_SRC_Y	P60484	PTEN	P12931	SRC	Y240	R234G	234	Missense	distal	-6	no	21.485	21.483	EPSD;PhosphoSitePlus	COSMIC;CCLE	20.673	Down-regulation
TK_Src_SrcA_SRC_Y	P60484	PTEN	P12931	SRC	Y240	F243L	243	Missense	distal	3	no	21.485	21.245	EPSD;PhosphoSitePlus	COSMIC	20.673	Down-regulation
TK_Src_SrcA_SRC_Y	P60484	PTEN	P12931	SRC	Y240	E235G	235	Missense	distal	-5	no	21.485	21.232	EPSD;PhosphoSitePlus	COSMIC	20.673	Down-regulation
TK_Src_SrcA_SRC_Y	P60484	PTEN	P12931	SRC	Y240	R234W	234	Missense	distal	-6	no	21.485	21.218	EPSD;PhosphoSitePlus	COSMIC	20.673	Down-regulation
TK_Src_SrcA_SRC_Y	P60484	PTEN	P12931	SRC	Y240	E235K	235	Missense	distal	-5	no	21.485	20.909	EPSD;PhosphoSitePlus	COSMIC	20.673	Down-regulation
TK_Src_SrcA_SRC_Y	P60484	PTEN	P12931	SRC	Y240	R234L	234	Missense	distal	-6	no	21.485	21.556	EPSD;PhosphoSitePlus	COSMIC	20.673	Up-regulation
TK_Src_SrcA_SRC_Y	P60484	PTEN	P12931	SRC	Y240	F241L	241	Missense	proximal	1	no	21.485	21.816	EPSD;PhosphoSitePlus	COSMIC;GDSC;CCLE	20.673	Up-regulation
TK_Src_SrcA_SRC_Y	P60484	PTEN	P12931	SRC	Y240	P244S	244	Missense	distal	4	no	21.485	21.507	EPSD;PhosphoSitePlus	COSMIC	20.673	Up-regulation
TK_Src_SrcA_SRC_Y	P60484	PTEN	P12931	SRC	Y240	L247S	247	Missense	distal	7	no	21.485	21.472	EPSD;PhosphoSitePlus	COSMIC	20.673	Down-regulation
TK_Src_SrcA_SRC_Y	P60484	PTEN	P12931	SRC	Y315	L318F	318	Missense	distal	3	no	24.283	24.524	EPSD;PhosphoSitePlus	COSMIC	20.673	Up-regulation
TK_Src_SrcA_SRC_Y	P60484	PTEN	P12931	SRC	Y315	L320V	320	Missense	distal	5	no	24.283	24.188	EPSD;PhosphoSitePlus	COSMIC	20.673	Down-regulation
TK_Src_SrcA_SRC_Y	P60484	PTEN	P12931	SRC	Y315	Y315H	315	Missense	central	0	yes	24.283	0.000	EPSD;PhosphoSitePlus	COSMIC	20.673	Loss
TK_Src_SrcA_SRC_Y	P60484	PTEN	P12931	SRC	Y315	L318P	318	Missense	distal	3	no	24.283	24.381	EPSD;PhosphoSitePlus	COSMIC	20.673	Up-regulation
TK_Src_SrcA_SRC_Y	P60484	PTEN	P12931	SRC	Y315	R308H	308	Missense	distal	-7	no	24.283	23.989	EPSD;PhosphoSitePlus	COSMIC	20.673	Down-regulation
TK_Src_SrcA_SRC_Y	P60484	PTEN	P12931	SRC	Y315	V317G	317	Missense	proximal	2	no	24.283	23.297	EPSD;PhosphoSitePlus	COSMIC	20.673	Down-regulation
TK_Src_SrcA_SRC_Y	P60484	PTEN	P12931	SRC	Y315	E314K	314	Missense	proximal	-1	no	24.283	22.375	EPSD;PhosphoSitePlus	COSMIC	20.673	Down-regulation
TK_Src_SrcA_SRC_Y	P60484	PTEN	P12931	SRC	Y315	T321I	321	Missense	distal	6	no	24.283	24.313	EPSD;PhosphoSitePlus	COSMIC	20.673	Up-regulation
TK_Src_SrcA_SRC_Y	P60484	PTEN	P12931	SRC	Y377	D375N	375	Missense	proximal	-2	no	20.933	20.653	EPSD;PhosphoSitePlus	COSMIC	20.673	Loss
TK_Src_SrcA_SRC_Y	P60484	PTEN	P12931	SRC	Y377	T383I	383	Missense	distal	6	no	20.933	20.963	EPSD;PhosphoSitePlus	COSMIC	20.673	Up-regulation
TK_Src_SrcA_SRC_Y	P60484	PTEN	P12931	SRC	Y377	D384N	384	Missense	distal	7	no	20.933	20.931	EPSD;PhosphoSitePlus	COSMIC	20.673	Down-regulation
TK_Src_SrcA_SRC_Y	P60484	PTEN	P12931	SRC	Y377	T382S	382	Missense	distal	5	no	20.933	20.763	EPSD;PhosphoSitePlus	COSMIC	20.673	Down-regulation
TK_Src_SrcA_SRC_Y	P60484	PTEN	P12931	SRC	Y377	D384G	384	Missense	distal	7	no	20.933	20.995	EPSD;PhosphoSitePlus	COSMIC	20.673	Up-regulation
TK_Src_SrcA_SRC_Y	P17302	GJA1	P12931	SRC	Y247	K243N	243	Missense	distal	-4	no	20.403	21.266	EPSD;PhosphoSitePlus	COSMIC	20.673	Gain
TK_Src_SrcA_SRC_Y	P17302	GJA1	P12931	SRC	Y265	D259Y	259	Missense	distal	-6	no	20.925	20.758	PhosphoSitePlus;EPSD	COSMIC	20.673	Down-regulation
TK_Src_SrcA_SRC_Y	Q13813	SPTAN1	P12931	SRC	Y644	I639V	639	Missense	distal	-5	no	20.825	21.034	EPSD	COSMIC	20.673	Up-regulation
TK_Src_SrcA_SRC_Y	Q13813	SPTAN1	P12931	SRC	Y1073	Y1073C	1073	Missense	central	0	yes	23.247	0.000	PhosphoSitePlus;EPSD	COSMIC	20.673	Loss
TK_Src_SrcA_SRC_Y	Q13813	SPTAN1	P12931	SRC	Y1176	P1180S	1180	Missense	distal	4	no	22.468	22.490	EPSD;PhosphoSitePlus	COSMIC;GDSC;CCLE	20.673	Up-regulation
TK_Src_SrcA_SRC_Y	Q13813	SPTAN1	P12931	SRC	Y1176	G1177D	1177	Missense	proximal	1	no	22.468	22.846	EPSD;PhosphoSitePlus	COSMIC	20.673	Up-regulation
TK_Src_SrcA_SRC_Y	Q13813	SPTAN1	P12931	SRC	Y1176	M1179V	1179	Missense	distal	3	no	22.468	22.835	EPSD;PhosphoSitePlus	COSMIC;GDSC;CCLE	20.673	Up-regulation
TK_Src_SrcA_SRC_Y	Q13813	SPTAN1	P12931	SRC	Y1579	P1582S	1582	Missense	distal	3	no	22.200	21.461	EPSD	COSMIC	20.673	Down-regulation
TK_Src_SrcA_SRC_Y	Q13813	SPTAN1	P12931	SRC	Y1792	G1793D	1793	Missense	proximal	1	no	21.111	21.489	EPSD	COSMIC	20.673	Up-regulation
TK_Src_SrcA_SRC_Y	Q13813	SPTAN1	P12931	SRC	Y1792	R1794W	1794	Missense	proximal	2	no	21.111	21.468	EPSD	COSMIC;CCLE	20.673	Up-regulation
TK_Src_SrcA_SRC_Y	Q13813	SPTAN1	P12931	SRC	Y1792	V1799M	1799	Missense	distal	7	no	21.111	21.112	EPSD	COSMIC	20.673	Up-regulation
TK_Src_SrcA_SRC_Y	Q13813	SPTAN1	P12931	SRC	Y1792	E1790Q	1790	Missense	proximal	-2	no	21.111	19.921	EPSD	COSMIC	20.673	Loss
TK_Src_SrcA_SRC_Y	Q13813	SPTAN1	P12931	SRC	Y1792	G1788D	1788	Missense	distal	-4	no	21.111	21.770	EPSD	COSMIC	20.673	Up-regulation
TK_Src_SrcA_SRC_Y	Q13813	SPTAN1	P12931	SRC	Y1898	D1897H	1897	Missense	proximal	-1	no	20.342	20.909	EPSD	COSMIC	20.673	Gain
TK_Src_SrcA_SRC_Y	Q13813	SPTAN1	P12931	SRC	Y1898	G1899D	1899	Missense	proximal	1	no	20.342	20.719	EPSD	COSMIC	20.673	Gain
TK_Src_SrcA_SRC_Y	Q13813	SPTAN1	P12931	SRC	Y2430	V2424M	2424	Missense	distal	-6	no	21.817	21.526	EPSD	COSMIC	20.673	Down-regulation
TK_Src_SrcA_SRC_Y	Q13813	SPTAN1	P12931	SRC	Y2440	C2441W	2441	Missense	proximal	1	no	19.455	20.675	EPSD	COSMIC	20.673	Gain
TK_Src_SrcA_SRC_Y	P16035	TIMP2	P12931	SRC	Y62	S57I	57	Missense	distal	-5	no	23.336	23.031	EPSD;PhosphoSitePlus	COSMIC	20.673	Down-regulation
TK_Src_SrcA_SRC_Y	P16035	TIMP2	P12931	SRC	Y62	P65H	65	Missense	distal	3	no	23.336	22.740	EPSD;PhosphoSitePlus	COSMIC	20.673	Down-regulation
TK_Src_SrcA_SRC_Y	P16035	TIMP2	P12931	SRC	Y62	G63C	63	Missense	proximal	1	no	23.336	21.040	EPSD;PhosphoSitePlus	COSMIC	20.673	Down-regulation
TK_Src_SrcA_SRC_Y	P35916	FLT4	P12931	SRC	Y833	A835V	835	Missense	proximal	2	no	21.340	21.551	EPSD;PhosphoSitePlus	COSMIC	20.673	Up-regulation
TK_Src_SrcA_SRC_Y	P35916	FLT4	P12931	SRC	Y833	E829Q	829	Missense	distal	-4	no	21.340	20.510	EPSD;PhosphoSitePlus	COSMIC	20.673	Loss
TK_Src_SrcA_SRC_Y	P35916	FLT4	P12931	SRC	Y853	G857W	857	Missense	distal	4	no	20.985	20.956	EPSD;PhosphoSitePlus	COSMIC	20.673	Down-regulation
TK_Src_SrcA_SRC_Y	P35916	FLT4	P12931	SRC	Y853	G852S	852	Missense	proximal	-1	no	20.985	21.528	EPSD;PhosphoSitePlus	COSMIC	20.673	Up-regulation
TK_Src_SrcA_SRC_Y	P35916	FLT4	P12931	SRC	Y853	G852A	852	Missense	proximal	-1	no	20.985	21.639	EPSD;PhosphoSitePlus	COSMIC	20.673	Up-regulation
TK_Src_SrcA_SRC_Y	P35916	FLT4	P12931	SRC	Y1063	L1058F	1058	Missense	distal	-5	no	20.766	20.701	EPSD;PhosphoSitePlus	COSMIC	20.673	Down-regulation
TK_Src_SrcA_SRC_Y	P35916	FLT4	P12931	SRC	Y1063	R1060L	1060	Missense	distal	-3	no	20.766	19.571	EPSD;PhosphoSitePlus	COSMIC	20.673	Loss
TK_Src_SrcA_SRC_Y	P35916	FLT4	P12931	SRC	Y1063	D1067E	1067	Missense	distal	4	no	20.766	20.738	EPSD;PhosphoSitePlus	COSMIC	20.673	Down-regulation
TK_Src_SrcA_SRC_Y	P35916	FLT4	P12931	SRC	Y1063	D1067V	1067	Missense	distal	4	no	20.766	20.722	EPSD;PhosphoSitePlus	COSMIC	20.673	Down-regulation
TK_Src_SrcA_SRC_Y	P35916	FLT4	P12931	SRC	Y1063	Y1068C	1068	Missense	distal	5	no	20.766	20.811	EPSD;PhosphoSitePlus	COSMIC	20.673	Up-regulation
TK_Src_SrcA_SRC_Y	P35916	FLT4	P12931	SRC	Y1068	R1075W	1075	Missense	distal	7	no	21.795	21.892	EPSD	COSMIC	20.673	Up-regulation
TK_Src_SrcA_SRC_Y	P35916	FLT4	P12931	SRC	Y1068	D1067E	1067	Missense	proximal	-1	no	21.795	22.704	EPSD	COSMIC	20.673	Up-regulation
TK_Src_SrcA_SRC_Y	P35916	FLT4	P12931	SRC	Y1068	D1067V	1067	Missense	proximal	-1	no	21.795	23.229	EPSD	COSMIC	20.673	Up-regulation
TK_Src_SrcA_SRC_Y	P35916	FLT4	P12931	SRC	Y1068	Y1068C	1068	Missense	central	0	yes	21.795	0.000	EPSD	COSMIC	20.673	Loss
TK_Src_SrcA_SRC_Y	P35916	FLT4	P12931	SRC	Y1231	A1227D	1227	Missense	distal	-4	no	20.502	21.844	EPSD	COSMIC	20.673	Gain
TK_Src_SrcA_SRC_Y	P35916	FLT4	P12931	SRC	Y1337	Y1333H	1333	Missense	distal	-4	no	21.735	21.567	EPSD;PhosphoSitePlus	COSMIC	20.673	Down-regulation
TK_Src_SrcA_SRC_Y	P35916	FLT4	P12931	SRC	Y1337	F1332L	1332	Missense	distal	-5	no	21.735	21.800	EPSD;PhosphoSitePlus	COSMIC	20.673	Up-regulation
TK_Src_SrcA_SRC_Y	P35916	FLT4	P12931	SRC	Y1337	S1341L	1341	Missense	distal	4	no	21.735	21.742	EPSD;PhosphoSitePlus	COSMIC	20.673	Up-regulation
TK_Src_SrcA_SRC_Y	P01112	HRAS	P12931	SRC	Y32	Q25H	25	Missense	distal	-7	no	20.815	20.745	EPSD;PhosphoSitePlus	COSMIC	20.673	Down-regulation
TK_Src_SrcA_SRC_Y	P01112	HRAS	P12931	SRC	Y32	N26D	26	Missense	distal	-6	no	20.815	21.005	EPSD;PhosphoSitePlus	COSMIC	20.673	Up-regulation
TK_Src_SrcA_SRC_Y	P01112	HRAS	P12931	SRC	Y32	P34S	34	Missense	proximal	2	no	20.815	21.422	EPSD;PhosphoSitePlus	COSMIC	20.673	Up-regulation
TK_Src_SrcA_SRC_Y	P01112	HRAS	P12931	SRC	Y32	D33Y	33	Missense	proximal	1	no	20.815	20.417	EPSD;PhosphoSitePlus	COSMIC	20.673	Loss
TK_Src_SrcA_SRC_Y	P01112	HRAS	P12931	SRC	Y32	I36V	36	Missense	distal	4	no	20.815	20.804	EPSD;PhosphoSitePlus	COSMIC	20.673	Down-regulation
TK_Src_SrcA_SRC_Y	P01112	HRAS	P12931	SRC	Y32	Y32C	32	Missense	central	0	yes	20.815	0.000	EPSD;PhosphoSitePlus	COSMIC	20.673	Loss
TK_Src_SrcA_SRC_Y	P01112	HRAS	P12931	SRC	Y32	Q25L	25	Missense	distal	-7	no	20.815	20.556	EPSD;PhosphoSitePlus	COSMIC	20.673	Loss
TK_Src_SrcA_SRC_Y	P01112	HRAS	P12931	SRC	Y64	D69N	69	Missense	distal	5	no	23.344	23.502	EPSD;PhosphoSitePlus	COSMIC	20.673	Up-regulation
TK_Src_SrcA_SRC_Y	P01112	HRAS	P12931	SRC	Y64	E62G	62	Missense	proximal	-2	no	23.344	22.767	EPSD;PhosphoSitePlus	COSMIC	20.673	Down-regulation
TK_Src_SrcA_SRC_Y	P01112	HRAS	P12931	SRC	Y64	Q61P	61	Missense	distal	-3	no	23.344	22.684	EPSD;PhosphoSitePlus	COSMIC	20.673	Down-regulation
TK_Src_SrcA_SRC_Y	P01112	HRAS	P12931	SRC	Y64	G60D	60	Missense	distal	-4	no	23.344	24.003	EPSD;PhosphoSitePlus	COSMIC	20.673	Up-regulation
TK_Src_SrcA_SRC_Y	P01112	HRAS	P12931	SRC	Y64	D57N	57	Missense	distal	-7	no	23.344	23.264	EPSD;PhosphoSitePlus	COSMIC	20.673	Down-regulation
TK_Src_SrcA_SRC_Y	P01112	HRAS	P12931	SRC	Y64	A59D	59	Missense	distal	-5	no	23.344	23.527	EPSD;PhosphoSitePlus	COSMIC	20.673	Up-regulation
TK_Src_SrcA_SRC_Y	P01112	HRAS	P12931	SRC	Y64	R68W	68	Missense	distal	4	no	23.344	23.316	EPSD;PhosphoSitePlus	COSMIC	20.673	Down-regulation
TK_Src_SrcA_SRC_Y	P01112	HRAS	P12931	SRC	Y64	Q61E	61	Missense	distal	-3	no	23.344	24.224	EPSD;PhosphoSitePlus	COSMIC	20.673	Up-regulation
TK_Src_SrcA_SRC_Y	P01112	HRAS	P12931	SRC	Y64	T58I	58	Missense	distal	-6	no	23.344	23.374	EPSD;PhosphoSitePlus	COSMIC	20.673	Up-regulation
TK_Src_SrcA_SRC_Y	P01112	HRAS	P12931	SRC	Y64	Y64H	64	Missense	central	0	yes	23.344	0.000	EPSD;PhosphoSitePlus	COSMIC	20.673	Loss
TK_Src_SrcA_SRC_Y	P01112	HRAS	P12931	SRC	Y64	R68L	68	Missense	distal	4	no	23.344	23.377	EPSD;PhosphoSitePlus	COSMIC	20.673	Up-regulation
TK_Src_SrcA_SRC_Y	P01112	HRAS	P12931	SRC	Y64	R68Q	68	Missense	distal	4	no	23.344	23.366	EPSD;PhosphoSitePlus	COSMIC	20.673	Up-regulation
TK_Src_SrcA_SRC_Y	P01112	HRAS	P12931	SRC	Y64	D69H	69	Missense	distal	5	no	23.344	23.633	EPSD;PhosphoSitePlus	COSMIC	20.673	Up-regulation
TK_Src_SrcA_SRC_Y	P01112	HRAS	P12931	SRC	Y64	T58A	58	Missense	distal	-6	no	23.344	23.307	EPSD;PhosphoSitePlus	COSMIC	20.673	Down-regulation
TK_Src_SrcA_SRC_Y	P01112	HRAS	P12931	SRC	Y64	Q61X	61	Missense	distal	-3	no	23.344	22.282	EPSD;PhosphoSitePlus	COSMIC	20.673	Down-regulation
TK_Src_SrcA_SRC_Y	P01112	HRAS	P12931	SRC	Y157	F156L	156	Missense	proximal	-1	no	19.916	20.776	EPSD	COSMIC	20.673	Gain
TK_Src_SrcA_SRC_Y	Q9Y2W1	THRAP3	P12931	SRC	Y54	R50H	50	Missense	distal	-4	no	20.852	20.368	EPSD	COSMIC;GDSC;CCLE	20.673	Loss
TK_Src_SrcA_SRC_Y	Q9Y2W1	THRAP3	P12931	SRC	Y476	P479S	479	Missense	distal	3	no	22.466	21.727	EPSD	COSMIC	20.673	Down-regulation
TK_Src_SrcA_SRC_Y	Q9Y2W1	THRAP3	P12931	SRC	Y476	L474V	474	Missense	proximal	-2	no	22.466	22.546	EPSD	COSMIC	20.673	Up-regulation
TK_Src_SrcA_SRC_Y	Q9Y2W1	THRAP3	P12931	SRC	Y790	Y790H	790	Missense	central	0	yes	21.316	0.000	EPSD	COSMIC	20.673	Loss
TK_Src_SrcA_SRC_Y	Q9Y2W1	THRAP3	P12931	SRC	Y790	Q785K	785	Missense	distal	-5	no	21.316	21.167	EPSD	COSMIC	20.673	Down-regulation
TK_Src_SrcA_SRC_Y	Q9Y2W1	THRAP3	P12931	SRC	Y795	Y790H	790	Missense	distal	-5	no	20.766	21.431	EPSD	COSMIC	20.673	Up-regulation
TK_Src_SrcA_SRC_Y	P06396	GSN	P12931	SRC	Y86	D93N	93	Missense	distal	7	no	22.899	22.897	EPSD;PhosphoSitePlus	COSMIC	20.673	Down-regulation
TK_Src_SrcA_SRC_Y	P06396	GSN	P12931	SRC	Y86	T91M	91	Missense	distal	5	no	22.899	23.121	EPSD;PhosphoSitePlus	COSMIC	20.673	Up-regulation
TK_Src_SrcA_SRC_Y	P06396	GSN	P12931	SRC	Y86	P82S	82	Missense	distal	-4	no	22.899	22.952	EPSD;PhosphoSitePlus	COSMIC	20.673	Up-regulation
TK_Src_SrcA_SRC_Y	P06396	GSN	P12931	SRC	Y86	V81M	81	Missense	distal	-5	no	22.899	22.581	EPSD;PhosphoSitePlus	COSMIC	20.673	Down-regulation
TK_Src_SrcA_SRC_Y	P06396	GSN	P12931	SRC	Y465	P459R	459	Missense	distal	-6	no	24.763	24.672	PhosphoSitePlus;EPSD	COSMIC;GDSC;CCLE	20.673	Down-regulation
TK_Src_SrcA_SRC_Y	P06396	GSN	P12931	SRC	Y465	F468L	468	Missense	distal	3	no	24.763	24.523	PhosphoSitePlus;EPSD	COSMIC	20.673	Down-regulation
TK_Src_SrcA_SRC_Y	P06396	GSN	P12931	SRC	Y465	V460M	460	Missense	distal	-5	no	24.763	24.444	PhosphoSitePlus;EPSD	COSMIC;GDSC	20.673	Down-regulation
TK_Src_SrcA_SRC_Y	P06396	GSN	P12931	SRC	Y465	G470V	470	Missense	distal	5	no	24.763	24.654	PhosphoSitePlus;EPSD	COSMIC	20.673	Down-regulation
TK_Src_SrcA_SRC_Y	P06396	GSN	P12931	SRC	Y651	G647W	647	Missense	distal	-4	no	21.179	19.788	EPSD;PhosphoSitePlus	COSMIC	20.673	Loss
TK_Src_SrcA_SRC_Y	P06396	GSN	P12931	SRC	Y651	A649V	649	Missense	proximal	-2	no	21.179	20.881	EPSD;PhosphoSitePlus	COSMIC	20.673	Down-regulation
TK_Src_SrcA_SRC_Y	Q9H5V8	CDCP1	P12931	SRC	Y283	P286L	286	Missense	distal	3	no	20.689	20.592	EPSD	COSMIC;GDSC;CCLE	20.673	Loss
TK_Src_SrcA_SRC_Y	Q9H5V8	CDCP1	P12931	SRC	Y283	R280Q	280	Missense	distal	-3	no	20.689	21.306	EPSD	COSMIC	20.673	Up-regulation
TK_Src_SrcA_SRC_Y	Q9H5V8	CDCP1	P12931	SRC	Y283	E278K	278	Missense	distal	-5	no	20.689	20.113	EPSD	COSMIC	20.673	Loss
TK_Src_SrcA_SRC_Y	Q9H5V8	CDCP1	P12931	SRC	Y284	P286L	286	Missense	proximal	2	no	21.255	20.798	EPSD	COSMIC;GDSC;CCLE	20.673	Down-regulation
TK_Src_SrcA_SRC_Y	Q9H5V8	CDCP1	P12931	SRC	Y284	R280Q	280	Missense	distal	-4	no	21.255	20.876	EPSD	COSMIC	20.673	Down-regulation
TK_Src_SrcA_SRC_Y	Q9H5V8	CDCP1	P12931	SRC	Y284	E278K	278	Missense	distal	-6	no	21.255	21.242	EPSD	COSMIC	20.673	Down-regulation
TK_Src_SrcA_SRC_Y	Q9H5V8	CDCP1	P12931	SRC	Y707	P702S	702	Missense	distal	-5	no	20.619	20.721	EPSD	COSMIC	20.673	Gain
TK_Src_SrcA_SRC_Y	Q9H5V8	CDCP1	P12931	SRC	Y707	A703T	703	Missense	distal	-4	no	20.619	20.894	EPSD	COSMIC;GDSC	20.673	Gain
TK_Src_SrcA_SRC_Y	Q9H5V8	CDCP1	P12931	SRC	Y734	I737T	737	Missense	distal	3	no	24.372	23.907	PhosphoSitePlus;EPSD	COSMIC;CCLE	20.673	Down-regulation
TK_Src_SrcA_SRC_Y	Q9H5V8	CDCP1	P12931	SRC	Y734	N729S	729	Missense	distal	-5	no	24.372	24.501	PhosphoSitePlus;EPSD	COSMIC	20.673	Up-regulation
TK_Src_SrcA_SRC_Y	Q9H5V8	CDCP1	P12931	SRC	Y734	T740I	740	Missense	distal	6	no	24.372	24.402	PhosphoSitePlus;EPSD	COSMIC	20.673	Up-regulation
TK_Src_SrcA_SRC_Y	Q9H5V8	CDCP1	P12931	SRC	Y743	V742I	742	Missense	proximal	-1	no	21.825	21.451	EPSD;PhosphoSitePlus	COSMIC	20.673	Down-regulation
TK_Src_SrcA_SRC_Y	Q9H5V8	CDCP1	P12931	SRC	Y743	I737T	737	Missense	distal	-6	no	21.825	21.795	EPSD;PhosphoSitePlus	COSMIC;CCLE	20.673	Down-regulation
TK_Src_SrcA_SRC_Y	Q9H5V8	CDCP1	P12931	SRC	Y743	T740I	740	Missense	distal	-3	no	21.825	19.974	EPSD;PhosphoSitePlus	COSMIC	20.673	Loss
TK_Src_SrcA_SRC_Y	Q9H5V8	CDCP1	P12931	SRC	Y806	P811S	811	Missense	distal	5	no	22.731	22.553	EPSD	COSMIC	20.673	Down-regulation
TK_Src_SrcA_SRC_Y	Q9H5V8	CDCP1	P12931	SRC	Y806	S809F	809	Missense	distal	3	no	22.731	23.612	EPSD	COSMIC	20.673	Up-regulation
TK_Src_SrcA_SRC_Y	Q9H5V8	CDCP1	P12931	SRC	Y806	N812T	812	Missense	distal	6	no	22.731	22.738	EPSD	COSMIC	20.673	Up-regulation
TK_Src_SrcA_SRC_Y	Q9H5V8	CDCP1	P12931	SRC	Y806	Y806H	806	Missense	central	0	yes	22.731	0.000	EPSD	COSMIC	20.673	Loss
TK_Src_SrcA_SRC_Y	P41235	HNF4A	P12931	SRC	Y23	A17D	17	Missense	distal	-6	no	22.972	23.225	EPSD;PhosphoSitePlus	COSMIC;GDSC;CCLE	20.673	Up-regulation
TK_Src_SrcA_SRC_Y	P41235	HNF4A	P12931	SRC	Y23	T24S	24	Missense	proximal	1	no	22.972	23.626	EPSD;PhosphoSitePlus	COSMIC;GDSC;CCLE	20.673	Up-regulation
TK_Src_SrcA_SRC_Y	P41235	HNF4A	P12931	SRC	Y23	E27A	27	Missense	distal	4	no	22.972	22.983	EPSD;PhosphoSitePlus	COSMIC	20.673	Up-regulation
TK_Src_SrcA_SRC_Y	P41235	HNF4A	P12931	SRC	Y23	T25S	25	Missense	proximal	2	no	22.972	23.231	EPSD;PhosphoSitePlus	COSMIC	20.673	Up-regulation
TK_Src_SrcA_SRC_Y	P41235	HNF4A	P12931	SRC	Y23	L26R	26	Missense	distal	3	no	22.972	21.283	EPSD;PhosphoSitePlus	COSMIC	20.673	Down-regulation
TK_Src_SrcA_SRC_Y	P41235	HNF4A	P12931	SRC	Y144	R141G	141	Missense	distal	-3	no	20.346	21.239	EPSD	COSMIC	20.673	Gain
TK_Src_SrcA_SRC_Y	P41235	HNF4A	P12931	SRC	Y144	R141Q	141	Missense	distal	-3	no	20.346	20.962	EPSD	COSMIC	20.673	Gain
TK_Src_SrcA_SRC_Y	P41235	HNF4A	P12931	SRC	Y286	D283Y	283	Missense	distal	-3	no	23.521	22.132	EPSD;PhosphoSitePlus	COSMIC	20.673	Down-regulation
TK_Src_SrcA_SRC_Y	P41235	HNF4A	P12931	SRC	Y286	N284K	284	Missense	proximal	-2	no	23.521	22.729	EPSD;PhosphoSitePlus	COSMIC	20.673	Down-regulation
TK_Src_SrcA_SRC_Y	P41235	HNF4A	P12931	SRC	Y286	Q280H	280	Missense	distal	-6	no	23.521	23.386	EPSD;PhosphoSitePlus	COSMIC	20.673	Down-regulation
TK_Src_SrcA_SRC_Y	P41235	HNF4A	P12931	SRC	Y286	D282E	282	Missense	distal	-4	no	23.521	23.296	EPSD;PhosphoSitePlus	COSMIC	20.673	Down-regulation
TK_Src_SrcA_SRC_Y	P41235	HNF4A	P12931	SRC	Y446	A452D	452	Missense	distal	6	no	20.896	20.870	EPSD	COSMIC	20.673	Down-regulation
TK_Src_SrcA_SRC_Y	P41235	HNF4A	P12931	SRC	Y446	P450L	450	Missense	distal	4	no	20.896	20.924	EPSD	COSMIC	20.673	Up-regulation
TK_Src_SrcA_SRC_Y	P41235	HNF4A	P12931	SRC	Y446	G439C	439	Missense	distal	-7	no	20.896	20.376	EPSD	COSMIC	20.673	Loss
TK_Src_SrcA_SRC_Y	P25098	GRK2	P12931	SRC	Y86	F85C	85	Missense	proximal	-1	no	20.646	21.274	EPSD;PhosphoSitePlus	COSMIC;GDSC	20.673	Gain
TK_Src_SrcA_SRC_Y	P25098	GRK2	P12931	SRC	Y506	L499P	499	Missense	distal	-7	no	25.336	25.451	EPSD	COSMIC	20.673	Up-regulation
TK_Src_SrcA_SRC_Y	P25098	GRK2	P12931	SRC	Y506	E504G	504	Missense	proximal	-2	no	25.336	24.758	EPSD	COSMIC	20.673	Down-regulation
TK_Src_SrcA_SRC_Y	P29353	SHC1	P12931	SRC	Y349	E343K	343	Missense	distal	-6	no	24.617	24.605	EPSD;PhosphoSitePlus	COSMIC	20.673	Down-regulation
TK_Src_SrcA_SRC_Y	P29353	SHC1	P12931	SRC	Y349	N351Y	351	Missense	proximal	2	no	24.617	24.423	EPSD;PhosphoSitePlus	COSMIC	20.673	Down-regulation
TK_Src_SrcA_SRC_Y	P29353	SHC1	P12931	SRC	Y349	P354L	354	Missense	distal	5	no	24.617	24.632	EPSD;PhosphoSitePlus	COSMIC	20.673	Up-regulation
TK_Src_SrcA_SRC_Y	P29353	SHC1	P12931	SRC	Y349	E343D	343	Missense	distal	-6	no	24.617	24.694	EPSD;PhosphoSitePlus	COSMIC	20.673	Up-regulation
TK_Src_SrcA_SRC_Y	P29353	SHC1	P12931	SRC	Y350	E343K	343	Missense	distal	-7	no	21.289	21.125	EPSD;PhosphoSitePlus	COSMIC	20.673	Down-regulation
TK_Src_SrcA_SRC_Y	P29353	SHC1	P12931	SRC	Y350	E357D	357	Missense	distal	7	no	21.289	21.250	EPSD;PhosphoSitePlus	COSMIC;GDSC	20.673	Down-regulation
TK_Src_SrcA_SRC_Y	P29353	SHC1	P12931	SRC	Y350	N351Y	351	Missense	proximal	1	no	21.289	22.282	EPSD;PhosphoSitePlus	COSMIC	20.673	Up-regulation
TK_Src_SrcA_SRC_Y	P29353	SHC1	P12931	SRC	Y350	P354L	354	Missense	distal	4	no	21.289	21.317	EPSD;PhosphoSitePlus	COSMIC	20.673	Up-regulation
TK_Src_SrcA_SRC_Y	P29353	SHC1	P12931	SRC	Y350	E343D	343	Missense	distal	-7	no	21.289	21.260	EPSD;PhosphoSitePlus	COSMIC	20.673	Down-regulation
TK_Src_SrcA_SRC_Y	P29353	SHC1	P12931	SRC	Y427	V430I	430	Missense	distal	3	no	24.319	24.259	EPSD;PhosphoSitePlus	COSMIC	20.673	Down-regulation
TK_Src_SrcA_SRC_Y	P29353	SHC1	P12931	SRC	Y427	S426C	426	Missense	proximal	-1	no	24.319	24.426	EPSD;PhosphoSitePlus	COSMIC	20.673	Up-regulation
TK_Src_SrcA_SRC_Y	P29353	SHC1	P12931	SRC	Y427	S426P	426	Missense	proximal	-1	no	24.319	24.670	EPSD;PhosphoSitePlus	COSMIC	20.673	Up-regulation
TK_Src_SrcA_SRC_Y	Q12879	GRIN2A	P12931	SRC	Y730	A727S	727	Missense	distal	-3	no	20.443	21.348	EPSD	COSMIC	20.673	Gain
TK_Src_SrcA_SRC_Y	Q12879	GRIN2A	P12931	SRC	Y1118	T1119I	1119	Missense	proximal	1	no	21.911	21.122	EPSD	COSMIC	20.673	Down-regulation
TK_Src_SrcA_SRC_Y	Q12879	GRIN2A	P12931	SRC	Y1118	G1122S	1122	Missense	distal	4	no	21.911	21.936	EPSD	COSMIC	20.673	Up-regulation
TK_Src_SrcA_SRC_Y	Q12879	GRIN2A	P12931	SRC	Y1118	S1111R	1111	Missense	distal	-7	no	21.911	22.159	EPSD	COSMIC	20.673	Up-regulation
TK_Src_SrcA_SRC_Y	Q12879	GRIN2A	P12931	SRC	Y1118	P1113S	1113	Missense	distal	-5	no	21.911	22.013	EPSD	COSMIC	20.673	Up-regulation
TK_Src_SrcA_SRC_Y	Q12879	GRIN2A	P12931	SRC	Y1118	T1119P	1119	Missense	proximal	1	no	21.911	20.419	EPSD	COSMIC	20.673	Loss
TK_Src_SrcA_SRC_Y	Q12879	GRIN2A	P12931	SRC	Y1118	R1114I	1114	Missense	distal	-4	no	21.911	20.516	EPSD	COSMIC	20.673	Loss
TK_Src_SrcA_SRC_Y	Q12879	GRIN2A	P12931	SRC	Y1118	T1119N	1119	Missense	proximal	1	no	21.911	21.666	EPSD	COSMIC	20.673	Down-regulation
TK_Src_SrcA_SRC_Y	Q12879	GRIN2A	P12931	SRC	Y1118	K1116R	1116	Missense	proximal	-2	no	21.911	21.335	EPSD	COSMIC	20.673	Down-regulation
TK_Src_SrcA_SRC_Y	Q12879	GRIN2A	P12931	SRC	Y1118	K1124N	1124	Missense	distal	6	no	21.911	21.867	EPSD	COSMIC	20.673	Down-regulation
TK_Src_SrcA_SRC_Y	Q12879	GRIN2A	P12931	SRC	Y1118	K1116N	1116	Missense	proximal	-2	no	21.911	22.703	EPSD	COSMIC;GDSC;CCLE	20.673	Up-regulation
TK_Src_SrcA_SRC_Y	Q12879	GRIN2A	P12931	SRC	Y1184	K1189N	1189	Missense	distal	5	no	22.095	22.013	EPSD;PhosphoSitePlus	COSMIC	20.673	Down-regulation
TK_Src_SrcA_SRC_Y	Q12879	GRIN2A	P12931	SRC	Y1184	S1179F	1179	Missense	distal	-5	no	22.095	21.772	EPSD;PhosphoSitePlus	COSMIC	20.673	Down-regulation
TK_Src_SrcA_SRC_Y	Q12879	GRIN2A	P12931	SRC	Y1184	D1182Y	1182	Missense	proximal	-2	no	22.095	20.646	EPSD;PhosphoSitePlus	COSMIC	20.673	Loss
TK_Src_SrcA_SRC_Y	Q12879	GRIN2A	P12931	SRC	Y1184	K1185T	1185	Missense	proximal	1	no	22.095	22.738	EPSD;PhosphoSitePlus	COSMIC	20.673	Up-regulation
TK_Src_SrcA_SRC_Y	Q12879	GRIN2A	P12931	SRC	Y1184	F1191C	1191	Missense	distal	7	no	22.095	22.178	EPSD;PhosphoSitePlus	COSMIC	20.673	Up-regulation
TK_Src_SrcA_SRC_Y	Q12879	GRIN2A	P12931	SRC	Y1184	G1177R	1177	Missense	distal	-7	no	22.095	22.717	EPSD;PhosphoSitePlus	COSMIC	20.673	Up-regulation
TK_Src_SrcA_SRC_Y	Q12879	GRIN2A	P12931	SRC	Y1184	H1190Y	1190	Missense	distal	6	no	22.095	22.106	EPSD;PhosphoSitePlus	COSMIC	20.673	Up-regulation
TK_Src_SrcA_SRC_Y	Q12879	GRIN2A	P12931	SRC	Y1184	F1191I	1191	Missense	distal	7	no	22.095	22.108	EPSD;PhosphoSitePlus	COSMIC	20.673	Up-regulation
TK_Src_SrcA_SRC_Y	Q12879	GRIN2A	P12931	SRC	Y1187	K1189N	1189	Missense	proximal	2	no	20.698	21.794	EPSD	COSMIC	20.673	Up-regulation
TK_Src_SrcA_SRC_Y	Q12879	GRIN2A	P12931	SRC	Y1187	D1182Y	1182	Missense	distal	-5	no	20.698	20.075	EPSD	COSMIC	20.673	Loss
TK_Src_SrcA_SRC_Y	Q12879	GRIN2A	P12931	SRC	Y1187	K1185T	1185	Missense	proximal	-2	no	20.698	20.630	EPSD	COSMIC	20.673	Loss
TK_Src_SrcA_SRC_Y	Q12879	GRIN2A	P12931	SRC	Y1187	F1191C	1191	Missense	distal	4	no	20.698	20.684	EPSD	COSMIC	20.673	Down-regulation
TK_Src_SrcA_SRC_Y	Q12879	GRIN2A	P12931	SRC	Y1187	H1190Y	1190	Missense	distal	3	no	20.698	20.796	EPSD	COSMIC	20.673	Up-regulation
TK_Src_SrcA_SRC_Y	Q12879	GRIN2A	P12931	SRC	Y1187	L1193W	1193	Missense	distal	6	no	20.698	20.763	EPSD	COSMIC	20.673	Up-regulation
TK_Src_SrcA_SRC_Y	Q12879	GRIN2A	P12931	SRC	Y1187	F1191I	1191	Missense	distal	4	no	20.698	20.692	EPSD	COSMIC	20.673	Down-regulation
TK_Src_SrcA_SRC_Y	Q12879	GRIN2A	P12931	SRC	Y1267	G1263E	1263	Missense	distal	-4	no	23.865	24.299	EPSD;PhosphoSitePlus	COSMIC	20.673	Up-regulation
TK_Src_SrcA_SRC_Y	Q12879	GRIN2A	P12931	SRC	Y1267	P1260Q	1260	Missense	distal	-7	no	23.865	24.010	EPSD;PhosphoSitePlus	COSMIC	20.673	Up-regulation
TK_Src_SrcA_SRC_Y	Q12879	GRIN2A	P12931	SRC	Y1267	W1271G	1271	Missense	distal	4	no	23.865	23.895	EPSD;PhosphoSitePlus	COSMIC	20.673	Up-regulation
TK_Src_SrcA_SRC_Y	Q12879	GRIN2A	P12931	SRC	Y1267	E1264D	1264	Missense	distal	-3	no	23.865	23.911	EPSD;PhosphoSitePlus	COSMIC	20.673	Up-regulation
TK_Src_SrcA_SRC_Y	Q12879	GRIN2A	P12931	SRC	Y1292	H1290N	1290	Missense	proximal	-2	no	21.705	22.206	EPSD	COSMIC	20.673	Up-regulation
TK_Src_SrcA_SRC_Y	Q12879	GRIN2A	P12931	SRC	Y1292	R1285K	1285	Missense	distal	-7	no	21.705	21.371	EPSD	COSMIC	20.673	Down-regulation
TK_Src_SrcA_SRC_Y	Q12879	GRIN2A	P12931	SRC	Y1292	N1294K	1294	Missense	proximal	2	no	21.705	20.609	EPSD	COSMIC	20.673	Loss
TK_Src_SrcA_SRC_Y	Q12879	GRIN2A	P12931	SRC	Y1325	R1318W	1318	Missense	distal	-7	no	24.289	23.816	PhosphoSitePlus;EPSD	COSMIC	20.673	Down-regulation
TK_Src_SrcA_SRC_Y	Q12879	GRIN2A	P12931	SRC	Y1325	L1320M	1320	Missense	distal	-5	no	24.289	24.131	PhosphoSitePlus;EPSD	COSMIC	20.673	Down-regulation
TK_Src_SrcA_SRC_Y	Q12879	GRIN2A	P12931	SRC	Y1325	G1326S	1326	Missense	proximal	1	no	24.289	24.174	PhosphoSitePlus;EPSD	COSMIC	20.673	Down-regulation
TK_Src_SrcA_SRC_Y	Q12879	GRIN2A	P12931	SRC	Y1325	L1320P	1320	Missense	distal	-5	no	24.289	24.445	PhosphoSitePlus;EPSD	COSMIC	20.673	Up-regulation
TK_Src_SrcA_SRC_Y	Q12879	GRIN2A	P12931	SRC	Y1325	N1323Y	1323	Missense	proximal	-2	no	24.289	23.119	PhosphoSitePlus;EPSD	COSMIC	20.673	Down-regulation
TK_Src_SrcA_SRC_Y	Q12879	GRIN2A	P12931	SRC	Y1325	F1329L	1329	Missense	distal	4	no	24.289	24.307	PhosphoSitePlus;EPSD	COSMIC	20.673	Up-regulation
TK_Src_SrcA_SRC_Y	Q12879	GRIN2A	P12931	SRC	Y1325	G1326V	1326	Missense	proximal	1	no	24.289	23.391	PhosphoSitePlus;EPSD	COSMIC	20.673	Down-regulation
TK_Src_SrcA_SRC_Y	Q12879	GRIN2A	P12931	SRC	Y1387	S1390A	1390	Missense	distal	3	no	20.630	20.673	EPSD	COSMIC	20.673	Gain
TK_Src_SrcA_SRC_Y	Q12879	GRIN2A	P12931	SRC	Y1423	R1417Q	1417	Missense	distal	-6	no	23.431	23.534	EPSD;PhosphoSitePlus	COSMIC	20.673	Up-regulation
TK_Src_SrcA_SRC_Y	Q12879	GRIN2A	P12931	SRC	Y1423	D1421N	1421	Missense	proximal	-2	no	23.431	23.151	EPSD;PhosphoSitePlus	COSMIC	20.673	Down-regulation
TK_Src_SrcA_SRC_Y	Q12879	GRIN2A	P12931	SRC	Y1423	E1426K	1426	Missense	distal	3	no	23.431	22.094	EPSD;PhosphoSitePlus	COSMIC	20.673	Down-regulation
TK_Src_SrcA_SRC_Y	Q12879	GRIN2A	P12931	SRC	Y1423	N1420D	1420	Missense	distal	-3	no	23.431	23.939	EPSD;PhosphoSitePlus	COSMIC	20.673	Up-regulation
TK_Src_SrcA_SRC_Y	P40763	STAT3	P12931	SRC	Y68	E63D	63	Missense	distal	-5	no	21.630	21.530	PhosphoSitePlus;EPSD	COSMIC	20.673	Down-regulation
TK_Src_SrcA_SRC_Y	P40763	STAT3	P12931	SRC	Y79	R84Q	84	Missense	distal	5	no	21.754	21.779	EPSD	COSMIC	20.673	Up-regulation
TK_Src_SrcA_SRC_Y	P40763	STAT3	P12931	SRC	Y79	L78R	78	Missense	proximal	-1	no	21.754	20.102	EPSD	COSMIC	20.673	Loss
TK_Src_SrcA_SRC_Y	P40763	STAT3	P12931	SRC	Y79	R84L	84	Missense	distal	5	no	21.754	21.922	EPSD	COSMIC	20.673	Up-regulation
TK_Src_SrcA_SRC_Y	P40763	STAT3	P12931	SRC	Y446	H447Y	447	Missense	proximal	1	no	21.778	22.825	EPSD	COSMIC	20.673	Up-regulation
TK_Src_SrcA_SRC_Y	P40763	STAT3	P12931	SRC	Y446	I452F	452	Missense	distal	6	no	21.778	21.789	EPSD	COSMIC	20.673	Up-regulation
TK_Src_SrcA_SRC_Y	O15379	HDAC3	P12931	SRC	Y404	N411S	411	Missense	distal	7	no	22.247	22.279	EPSD	COSMIC	20.673	Up-regulation
TK_Src_SrcA_SRC_Y	O15379	HDAC3	P12931	SRC	Y404	P400F	400	Missense	distal	-4	no	22.247	21.381	EPSD	COSMIC	20.673	Down-regulation
TK_Src_SrcA_SRC_Y	P52732	KIF11	P12931	SRC	Y82	D80Y	80	Missense	proximal	-2	no	21.086	19.636	EPSD	COSMIC	20.673	Loss
TK_Src_SrcA_SRC_Y	P52732	KIF11	P12931	SRC	Y211	A218T	218	Missense	distal	7	no	23.526	23.507	PhosphoSitePlus;EPSD	COSMIC	20.673	Down-regulation
TK_Src_SrcA_SRC_Y	P52732	KIF11	P12931	SRC	Y399	R393H	393	Missense	distal	-6	no	22.269	22.236	EPSD	COSMIC	20.673	Down-regulation
TK_Src_SrcA_SRC_Y	P52732	KIF11	P12931	SRC	Y399	E402A	402	Missense	distal	3	no	22.269	22.354	EPSD	COSMIC	20.673	Up-regulation
TK_Src_SrcA_SRC_Y	P31645	SLC6A4	P12931	SRC	Y47	Y47C	47	Missense	central	0	yes	21.046	0.000	EPSD;PhosphoSitePlus	COSMIC	20.673	Loss
TK_Src_SrcA_SRC_Y	Q7Z3C6	ATG9A	P12931	SRC	Y8	F4L	4	Missense	distal	-4	no	21.985	22.216	PhosphoSitePlus;EPSD	COSMIC	20.673	Up-regulation
TK_Src_SrcA_SRC_Y	Q7Z3C6	ATG9A	P12931	SRC	Y15	P20L	20	Missense	distal	5	no	21.348	21.362	EPSD;PhosphoSitePlus	COSMIC;GDSC;CCLE	20.673	Up-regulation
TK_Src_SrcA_SRC_Y	Q7Z3C6	ATG9A	P12931	SRC	Y545	E541D	541	Missense	distal	-4	no	22.096	22.322	EPSD	COSMIC	20.673	Up-regulation
TK_Src_SrcA_SRC_Y	Q7Z3C6	ATG9A	P12931	SRC	Y545	A548S	548	Missense	distal	3	no	22.096	22.052	EPSD	COSMIC	20.673	Down-regulation
TK_Src_SrcA_SRC_Y	Q7Z3C6	ATG9A	P12931	SRC	Y545	G538W	538	Missense	distal	-7	no	22.096	22.244	EPSD	COSMIC	20.673	Up-regulation
TK_Src_SrcA_SRC_Y	Q7Z3C6	ATG9A	P12931	SRC	Y701	S707N	707	Missense	distal	6	no	20.740	20.723	EPSD	COSMIC	20.673	Down-regulation
TK_Src_SrcA_SRC_Y	P78347	GTF2I	P12931	SRC	Y248	E242K	242	Missense	distal	-6	no	22.681	22.669	PhosphoSitePlus;EPSD	COSMIC	20.673	Down-regulation
TK_Src_SrcA_SRC_Y	P78347	GTF2I	P12931	SRC	Y249	E242K	242	Missense	distal	-7	no	23.134	22.971	EPSD;PhosphoSitePlus	COSMIC	20.673	Down-regulation
TK_Src_SrcA_SRC_Y	P78347	GTF2I	P12931	SRC	Y398	H393Y	393	Missense	distal	-5	no	21.584	20.919	EPSD	COSMIC	20.673	Down-regulation
TK_Src_SrcA_SRC_Y	P78347	GTF2I	P12931	SRC	Y398	Q391P	391	Missense	distal	-7	no	21.584	21.440	EPSD	COSMIC	20.673	Down-regulation
TK_Src_SrcA_SRC_Y	P78347	GTF2I	P12931	SRC	Y398	L397F	397	Missense	proximal	-1	no	21.584	20.725	EPSD	COSMIC	20.673	Down-regulation
TK_Src_SrcA_SRC_Y	P16885	PLCG2	P12931	SRC	Y680	S679F	679	Missense	proximal	-1	no	21.180	20.658	EPSD	COSMIC	20.673	Loss
TK_Src_SrcA_SRC_Y	P16885	PLCG2	P12931	SRC	Y680	T683A	683	Missense	distal	3	no	21.180	21.136	EPSD	COSMIC	20.673	Down-regulation
TK_Src_SrcA_SRC_Y	P16885	PLCG2	P12931	SRC	Y680	Y680F	680	Missense	central	0	yes	21.180	0.000	EPSD	COSMIC	20.673	Loss
TK_Src_SrcA_SRC_Y	P16885	PLCG2	P12931	SRC	Y680	D678N	678	Missense	proximal	-2	no	21.180	20.900	EPSD	COSMIC	20.673	Down-regulation
TK_Src_SrcA_SRC_Y	P16885	PLCG2	P12931	SRC	Y720	S718G	718	Missense	proximal	-2	no	21.309	21.921	EPSD	COSMIC	20.673	Up-regulation
TK_Src_SrcA_SRC_Y	P16885	PLCG2	P12931	SRC	Y753	M758I	758	Missense	distal	5	no	21.079	20.835	PhosphoSitePlus;EPSD	COSMIC	20.673	Down-regulation
TK_Src_SrcA_SRC_Y	P16885	PLCG2	P12931	SRC	Y753	S751F	751	Missense	proximal	-2	no	21.079	20.099	PhosphoSitePlus;EPSD	COSMIC	20.673	Loss
TK_Src_SrcA_SRC_Y	P16885	PLCG2	P12931	SRC	Y1048	E1041Q	1041	Missense	distal	-7	no	22.202	22.148	EPSD	COSMIC	20.673	Down-regulation
TK_Src_SrcA_SRC_Y	P16885	PLCG2	P12931	SRC	Y1048	E1041K	1041	Missense	distal	-7	no	22.202	22.038	EPSD	COSMIC	20.673	Down-regulation
TK_Src_SrcA_SRC_Y	P16885	PLCG2	P12931	SRC	Y1048	E1054Q	1054	Missense	distal	6	no	22.202	22.184	EPSD	COSMIC	20.673	Down-regulation
TK_Src_SrcA_SRC_Y	P16885	PLCG2	P12931	SRC	Y1197	E1191D	1191	Missense	distal	-6	no	23.077	23.154	EPSD	COSMIC	20.673	Up-regulation
TK_Src_SrcA_SRC_Y	P16885	PLCG2	P12931	SRC	Y1197	L1203P	1203	Missense	distal	6	no	23.077	23.061	EPSD	COSMIC	20.673	Down-regulation
TK_Src_SrcA_SRC_Y	P19022	CDH2	P12931	SRC	Y496	I489F	489	Missense	distal	-7	no	21.765	21.688	EPSD	COSMIC	20.673	Down-regulation
TK_Src_SrcA_SRC_Y	P19022	CDH2	P12931	SRC	Y496	N492H	492	Missense	distal	-4	no	21.765	21.137	EPSD	COSMIC	20.673	Down-regulation
TK_Src_SrcA_SRC_Y	P19022	CDH2	P12931	SRC	Y785	E780D	780	Missense	distal	-5	no	21.935	21.834	EPSD	COSMIC	20.673	Down-regulation
TK_Src_SrcA_SRC_Y	P19022	CDH2	P12931	SRC	Y785	D782N	782	Missense	distal	-3	no	21.935	21.426	EPSD	COSMIC	20.673	Down-regulation
TK_Src_SrcA_SRC_Y	P19022	CDH2	P12931	SRC	Y785	D782V	782	Missense	distal	-3	no	21.935	20.010	EPSD	COSMIC	20.673	Loss
TK_Src_SrcA_SRC_Y	P19022	CDH2	P12931	SRC	Y785	D786N	786	Missense	proximal	1	no	21.935	20.543	EPSD	COSMIC;GDSC;CCLE	20.673	Loss
TK_Src_SrcA_SRC_Y	P19022	CDH2	P12931	SRC	Y852	N845S	845	Missense	distal	-7	no	23.090	23.122	EPSD;PhosphoSitePlus	COSMIC	20.673	Up-regulation
TK_Src_SrcA_SRC_Y	P19022	CDH2	P12931	SRC	Y852	V857L	857	Missense	distal	5	no	23.090	23.185	EPSD;PhosphoSitePlus	COSMIC	20.673	Up-regulation
TK_Src_SrcA_SRC_Y	P19022	CDH2	P12931	SRC	Y852	P850S	850	Missense	proximal	-2	no	23.090	22.304	EPSD;PhosphoSitePlus	COSMIC	20.673	Down-regulation
TK_Src_SrcA_SRC_Y	P19022	CDH2	P12931	SRC	Y852	L856P	856	Missense	distal	4	no	23.090	23.061	EPSD;PhosphoSitePlus	COSMIC	20.673	Down-regulation
TK_Src_SrcA_SRC_Y	P19022	CDH2	P12931	SRC	Y884	D889E	889	Missense	distal	5	no	22.289	22.496	PhosphoSitePlus;EPSD	COSMIC	20.673	Up-regulation
TK_Src_SrcA_SRC_Y	P19022	CDH2	P12931	SRC	Y884	Y886S	886	Missense	proximal	2	no	22.289	22.730	PhosphoSitePlus;EPSD	COSMIC	20.673	Up-regulation
TK_Src_SrcA_SRC_Y	P19022	CDH2	P12931	SRC	Y884	G879C	879	Missense	distal	-5	no	22.289	21.554	PhosphoSitePlus;EPSD	COSMIC	20.673	Down-regulation
TK_Src_SrcA_SRC_Y	P19022	CDH2	P12931	SRC	Y884	L887P	887	Missense	distal	3	no	22.289	22.386	PhosphoSitePlus;EPSD	COSMIC	20.673	Up-regulation
TK_Src_SrcA_SRC_Y	P19022	CDH2	P12931	SRC	Y884	W890C	890	Missense	distal	6	no	22.289	22.267	PhosphoSitePlus;EPSD	COSMIC	20.673	Down-regulation
TK_Src_SrcA_SRC_Y	P19022	CDH2	P12931	SRC	Y884	W890L	890	Missense	distal	6	no	22.289	22.224	PhosphoSitePlus;EPSD	COSMIC	20.673	Down-regulation
TK_Src_SrcA_SRC_Y	P30411	BDKRB2	P12931	SRC	Y347	G349R	349	Missense	proximal	2	no	20.555	20.852	PhosphoSitePlus;EPSD	COSMIC	20.673	Gain
TK_Src_SrcA_SRC_Y	Q96J92	WNK4	P12931	SRC	Y375	A381V	381	Missense	distal	6	no	20.778	20.788	EPSD	COSMIC	20.673	Up-regulation
TK_Src_SrcA_SRC_Y	Q03135	CAV1	P12931	SRC	Y14	H12Q	12	Missense	proximal	-2	no	22.478	22.358	PhosphoSitePlus	COSMIC	20.673	Down-regulation
TK_Src_SrcA_SRC_Y	Q03135	CAV1	P12931	SRC	Y14	Q21L	21	Missense	distal	7	no	22.478	22.496	PhosphoSitePlus	COSMIC	20.673	Up-regulation
TK_Src_SrcA_SRC_Y	Q03135	CAV1	P12931	SRC	Y14	L13H	13	Missense	proximal	-1	no	22.478	22.722	PhosphoSitePlus	COSMIC	20.673	Up-regulation
TK_Src_SrcA_SRC_Y	Q03135	CAV1	P12931	SRC	Y25	Q21L	21	Missense	distal	-4	no	21.787	21.209	EPSD	COSMIC	20.673	Down-regulation
TK_Src_SrcA_SRC_Y	Q03135	CAV1	P12931	SRC	Y42	D43G	43	Missense	proximal	1	no	23.755	23.377	EPSD	COSMIC	20.673	Down-regulation
TK_Src_SrcA_SRC_Y	P35790	CHKA	P12931	SRC	Y333	I329T	329	Missense	distal	-4	no	20.473	21.478	EPSD;PhosphoSitePlus	COSMIC	20.673	Gain
TK_Src_SrcA_SRC_Y	Q9Y2X7	GIT1	P12931	SRC	Y224	R229W	229	Missense	distal	5	no	21.866	22.458	EPSD	COSMIC;GDSC;CCLE	20.673	Up-regulation
TK_Src_SrcA_SRC_Y	Q9Y2X7	GIT1	P12931	SRC	Y284	E278K	278	Missense	distal	-6	no	23.461	23.449	PhosphoSitePlus;EPSD	COSMIC	20.673	Down-regulation
TK_Src_SrcA_SRC_Y	Q9Y2X7	GIT1	P12931	SRC	Y284	Y284H	284	Missense	central	0	yes	23.461	0.000	PhosphoSitePlus;EPSD	COSMIC	20.673	Loss
TK_Src_SrcA_SRC_Y	Q9Y2X7	GIT1	P12931	SRC	Y545	V547L	547	Missense	proximal	2	no	22.449	21.527	EPSD	COSMIC	20.673	Down-regulation
TK_Src_SrcA_SRC_Y	Q9Y2X7	GIT1	P12931	SRC	Y598	D595N	595	Missense	distal	-3	no	22.344	21.836	EPSD	COSMIC	20.673	Down-regulation
TK_Src_SrcA_SRC_Y	Q9Y2X7	GIT1	P12931	SRC	Y598	Y598H	598	Missense	central	0	yes	22.344	0.000	EPSD	COSMIC	20.673	Loss
TK_Src_SrcA_SRC_Y	P15941	MUC1	P12931	SRC	Y1229	P1228R	1228	Missense	proximal	-1	no	20.818	19.152	PhosphoSitePlus	COSMIC	20.673	Loss
TK_Src_SrcA_SRC_Y	Q13480	GAB1	P12931	SRC	Y259	S264L	264	Missense	distal	5	no	20.690	20.882	EPSD;PhosphoSitePlus	COSMIC	20.673	Up-regulation
TK_Src_SrcA_SRC_Y	Q13480	GAB1	P12931	SRC	Y285	T289I	289	Missense	distal	4	no	22.654	22.642	EPSD	COSMIC	20.673	Down-regulation
TK_Src_SrcA_SRC_Y	Q13480	GAB1	P12931	SRC	Y406	P413L	413	Missense	distal	7	no	21.248	21.242	EPSD	COSMIC	20.673	Down-regulation
TK_Src_SrcA_SRC_Y	Q13480	GAB1	P12931	SRC	Y447	P449H	449	Missense	proximal	2	no	20.885	20.508	EPSD	COSMIC	20.673	Loss
TK_Src_SrcA_SRC_Y	Q13480	GAB1	P12931	SRC	Y447	E441Q	441	Missense	distal	-6	no	20.885	20.760	EPSD	COSMIC	20.673	Down-regulation
TK_Src_SrcA_SRC_Y	Q13480	GAB1	P12931	SRC	Y589	L596M	596	Missense	distal	7	no	22.225	22.278	EPSD	COSMIC	20.673	Up-regulation
TK_Src_SrcA_SRC_Y	Q13480	GAB1	P12931	SRC	Y589	N595D	595	Missense	distal	6	no	22.225	22.221	EPSD	COSMIC	20.673	Down-regulation
TK_Src_SrcA_SRC_Y	Q13480	GAB1	P12931	SRC	Y589	P591H	591	Missense	proximal	2	no	22.225	21.849	EPSD	COSMIC	20.673	Down-regulation
TK_Src_SrcA_SRC_Y	Q13480	GAB1	P12931	SRC	Y589	N593S	593	Missense	distal	4	no	22.225	22.193	EPSD	COSMIC	20.673	Down-regulation
TK_Src_SrcA_SRC_Y	Q13480	GAB1	P12931	SRC	Y589	S585R	585	Missense	distal	-4	no	22.225	22.495	EPSD	COSMIC	20.673	Up-regulation
TK_Src_SrcA_SRC_Y	Q13480	GAB1	P12931	SRC	Y589	N588K	588	Missense	proximal	-1	no	22.225	22.176	EPSD	COSMIC	20.673	Down-regulation
TK_Src_SrcA_SRC_Y	O43823	AKAP8	P12931	SRC	Y146	D153N	153	Missense	distal	7	no	21.034	21.031	EPSD;PhosphoSitePlus	COSMIC;GDSC;CCLE	20.673	Down-regulation
TK_Src_SrcA_SRC_Y	O43823	AKAP8	P12931	SRC	Y146	N144S	144	Missense	proximal	-2	no	21.034	20.411	EPSD;PhosphoSitePlus	COSMIC	20.673	Loss
TK_Src_SrcA_SRC_Y	O43823	AKAP8	P12931	SRC	Y150	D153N	153	Missense	distal	3	no	20.245	21.321	EPSD;PhosphoSitePlus	COSMIC;GDSC;CCLE	20.673	Gain
TK_Src_SrcA_SRC_Y	O43823	AKAP8	P12931	SRC	Y170	A177T	177	Missense	distal	7	no	21.005	20.986	EPSD;PhosphoSitePlus	COSMIC	20.673	Down-regulation
TK_Src_SrcA_SRC_Y	O43823	AKAP8	P12931	SRC	Y170	R174Q	174	Missense	distal	4	no	21.005	21.027	EPSD;PhosphoSitePlus	COSMIC;CCLE	20.673	Up-regulation
TK_Src_SrcA_SRC_Y	O43823	AKAP8	P12931	SRC	Y170	C173Y	173	Missense	distal	3	no	21.005	22.081	EPSD;PhosphoSitePlus	COSMIC	20.673	Up-regulation
TK_Src_SrcA_SRC_Y	O43823	AKAP8	P12931	SRC	Y170	D175N	175	Missense	distal	5	no	21.005	21.163	EPSD;PhosphoSitePlus	COSMIC	20.673	Up-regulation
TK_Src_SrcA_SRC_Y	O43823	AKAP8	P12931	SRC	Y170	G168W	168	Missense	proximal	-2	no	21.005	18.697	EPSD;PhosphoSitePlus	COSMIC	20.673	Loss
TK_Src_SrcA_SRC_Y	O43823	AKAP8	P12931	SRC	Y311	F308C	308	Missense	distal	-3	no	20.837	20.710	EPSD;PhosphoSitePlus	COSMIC	20.673	Down-regulation
TK_Src_SrcA_SRC_Y	O43823	AKAP8	P12931	SRC	Y311	R305W	305	Missense	distal	-6	no	20.837	20.570	EPSD;PhosphoSitePlus	COSMIC;CCLE	20.673	Loss
TK_Src_SrcA_SRC_Y	O43823	AKAP8	P12931	SRC	Y311	E312K	312	Missense	proximal	1	no	20.837	18.443	EPSD;PhosphoSitePlus	COSMIC	20.673	Loss
TK_Src_SrcA_SRC_Y	P52757	CHN2	P12931	SRC	Y21	W26L	26	Missense	distal	5	no	24.455	24.031	PhosphoSitePlus	COSMIC	20.673	Down-regulation
TK_Src_SrcA_SRC_Y	P52757	CHN2	P12931	SRC	Y21	P24S	24	Missense	distal	3	no	24.455	23.717	PhosphoSitePlus	COSMIC	20.673	Down-regulation
TK_Src_SrcA_SRC_Y	P52757	CHN2	P12931	SRC	Y21	P23H	23	Missense	proximal	2	no	24.455	24.079	PhosphoSitePlus	COSMIC	20.673	Down-regulation
TK_Src_SrcA_SRC_Y	P52757	CHN2	P12931	SRC	Y153	T149I	149	Missense	distal	-4	no	23.128	22.123	EPSD	COSMIC	20.673	Down-regulation
TK_Src_SrcA_SRC_Y	P52757	CHN2	P12931	SRC	Y153	P151T	151	Missense	proximal	-2	no	23.128	22.105	EPSD	COSMIC	20.673	Down-regulation
TK_Src_SrcA_SRC_Y	Q92945	KHSRP	P12931	SRC	Y149	P152S	152	Missense	distal	3	no	21.215	20.476	EPSD	COSMIC	20.673	Loss
TK_Src_SrcA_SRC_Y	Q92945	KHSRP	P12931	SRC	Y317	G312R	312	Missense	distal	-5	no	21.728	21.713	EPSD;PhosphoSitePlus	COSMIC	20.673	Down-regulation
TK_Src_SrcA_SRC_Y	Q92945	KHSRP	P12931	SRC	Y317	G310A	310	Missense	distal	-7	no	21.728	21.778	EPSD;PhosphoSitePlus	COSMIC	20.673	Up-regulation
TK_Src_SrcA_SRC_Y	P61978	HNRNPK	P12931	SRC	Y72	N73D	73	Missense	proximal	1	no	19.756	21.148	EPSD;PhosphoSitePlus	COSMIC	20.673	Gain
TK_Src_SrcA_SRC_Y	P61978	HNRNPK	P12931	SRC	Y369	S372A	372	Missense	distal	3	no	20.658	20.702	EPSD	COSMIC	20.673	Gain
TK_Src_SrcA_SRC_Y	P26010	ITGB7	P12931	SRC	Y753	V750G	750	Missense	distal	-3	no	20.131	21.407	EPSD;PhosphoSitePlus	COSMIC	20.673	Gain
TK_Src_SrcA_SRC_Y	P26010	ITGB7	P12931	SRC	Y758	R755G	755	Missense	distal	-3	no	23.252	24.145	PhosphoSitePlus;EPSD	COSMIC	20.673	Up-regulation
TK_Src_SrcA_SRC_Y	P26010	ITGB7	P12931	SRC	Y758	E762D	762	Missense	distal	4	no	23.252	23.280	PhosphoSitePlus;EPSD	COSMIC;GDSC;CCLE	20.673	Up-regulation
TK_Src_SrcA_SRC_Y	P26010	ITGB7	P12931	SRC	Y758	Y753H	753	Missense	distal	-5	no	23.252	23.917	PhosphoSitePlus;EPSD	COSMIC	20.673	Up-regulation
TK_Src_SrcA_SRC_Y	P26010	ITGB7	P12931	SRC	Y758	Y758N	758	Missense	central	0	yes	23.252	0.000	PhosphoSitePlus;EPSD	COSMIC	20.673	Loss
TK_Src_SrcA_SRC_Y	P23246	SFPQ	P12931	SRC	Y293	R287S	287	Missense	distal	-6	no	21.695	21.835	EPSD	COSMIC	20.673	Up-regulation
TK_Src_SrcA_SRC_Y	P23246	SFPQ	P12931	SRC	Y488	R493Q	493	Missense	distal	5	no	21.123	21.148	EPSD	COSMIC;GDSC;CCLE	20.673	Up-regulation
TK_Src_SrcA_SRC_Y	P23246	SFPQ	P12931	SRC	Y527	S521N	521	Missense	distal	-6	no	21.869	21.842	EPSD	COSMIC;GDSC;CCLE	20.673	Down-regulation
TK_Src_SrcA_SRC_Y	O14641	DVL2	P12931	SRC	Y27	Y27C	27	Missense	central	0	yes	20.822	0.000	EPSD;PhosphoSitePlus	COSMIC	20.673	Loss
TK_Src_SrcA_SRC_Y	O14641	DVL2	P12931	SRC	Y27	E24G	24	Missense	distal	-3	no	20.822	20.218	EPSD;PhosphoSitePlus	COSMIC	20.673	Loss
TK_Src_SrcA_SRC_Y	P15311	EZR	P12931	SRC	Y116	P119S	119	Missense	distal	3	no	20.745	20.007	EPSD	COSMIC	20.673	Loss
TK_Src_SrcA_SRC_Y	P15311	EZR	P12931	SRC	Y478	P480L	480	Missense	proximal	2	no	25.069	24.612	PhosphoSitePlus;EPSD	COSMIC	20.673	Down-regulation
TK_Src_SrcA_SRC_Y	Q15139	PRKD1	P12931	SRC	Y463	G459E	459	Missense	distal	-4	no	21.351	21.785	EPSD;PhosphoSitePlus	COSMIC	20.673	Up-regulation
TK_Src_SrcA_SRC_Y	Q15139	PRKD1	P12931	SRC	Y463	P467S	467	Missense	distal	4	no	21.351	21.373	EPSD;PhosphoSitePlus	COSMIC	20.673	Up-regulation
TK_Src_SrcA_SRC_Y	Q15139	PRKD1	P12931	SRC	Y463	K464N	464	Missense	proximal	1	no	21.351	21.749	EPSD;PhosphoSitePlus	COSMIC	20.673	Up-regulation
TK_Src_SrcA_SRC_Y	Q15139	PRKD1	P12931	SRC	Y502	V499I	499	Missense	distal	-3	no	21.516	20.411	EPSD;PhosphoSitePlus	COSMIC	20.673	Loss
TK_Src_SrcA_SRC_Y	Q15139	PRKD1	P12931	SRC	Y502	T495I	495	Missense	distal	-7	no	21.516	21.164	EPSD;PhosphoSitePlus	COSMIC	20.673	Down-regulation
TK_Src_SrcA_SRC_Y	Q15139	PRKD1	P12931	SRC	Y502	Y501S	501	Missense	proximal	-1	no	21.516	20.340	EPSD;PhosphoSitePlus	COSMIC	20.673	Loss
TK_Src_SrcA_SRC_Y	Q15139	PRKD1	P12931	SRC	Y502	T495P	495	Missense	distal	-7	no	21.516	21.299	EPSD;PhosphoSitePlus	COSMIC	20.673	Down-regulation
TK_Src_SrcA_SRC_Y	Q15139	PRKD1	P12931	SRC	Y749	A748T	748	Missense	proximal	-1	no	21.703	21.686	EPSD	COSMIC	20.673	Down-regulation
TK_Src_SrcA_SRC_Y	Q15139	PRKD1	P12931	SRC	Y749	V743L	743	Missense	distal	-6	no	21.703	21.884	EPSD	COSMIC	20.673	Up-regulation
TK_Src_SrcA_SRC_Y	Q15139	PRKD1	P12931	SRC	Y749	T746I	746	Missense	distal	-3	no	21.703	19.852	EPSD	COSMIC	20.673	Loss
TK_Src_SrcA_SRC_Y	Q15139	PRKD1	P12931	SRC	Y749	R756G	756	Missense	distal	7	no	21.703	21.696	EPSD	COSMIC	20.673	Down-regulation
TK_Src_SrcA_SRC_Y	Q93052	LPP	P12931	SRC	Y244	S239L	239	Missense	distal	-5	no	22.155	21.896	PhosphoSitePlus;EPSD	COSMIC	20.673	Down-regulation
TK_Src_SrcA_SRC_Y	Q93052	LPP	P12931	SRC	Y287	P283L	283	Missense	distal	-4	no	21.800	21.166	EPSD	COSMIC	20.673	Down-regulation
TK_Src_SrcA_SRC_Y	Q93052	LPP	P12931	SRC	Y287	Q293L	293	Missense	distal	6	no	21.800	21.821	EPSD	COSMIC	20.673	Up-regulation
TK_Src_SrcA_SRC_Y	Q93052	LPP	P12931	SRC	Y287	L281I	281	Missense	distal	-6	no	21.800	21.847	EPSD	COSMIC	20.673	Up-regulation
TK_Src_SrcA_SRC_Y	Q93052	LPP	P12931	SRC	Y287	P283S	283	Missense	distal	-4	no	21.800	21.853	EPSD	COSMIC	20.673	Up-regulation
TK_Src_SrcA_SRC_Y	Q93052	LPP	P12931	SRC	Y296	Y297C	297	Missense	proximal	1	no	21.345	19.069	EPSD	COSMIC	20.673	Loss
TK_Src_SrcA_SRC_Y	Q93052	LPP	P12931	SRC	Y296	R295L	295	Missense	proximal	-1	no	21.345	22.997	EPSD	COSMIC	20.673	Up-regulation
TK_Src_SrcA_SRC_Y	Q93052	LPP	P12931	SRC	Y296	Q293L	293	Missense	distal	-3	no	21.345	19.534	EPSD	COSMIC	20.673	Loss
TK_Src_SrcA_SRC_Y	Q93052	LPP	P12931	SRC	Y296	R295H	295	Missense	proximal	-1	no	21.345	23.241	EPSD	COSMIC	20.673	Up-regulation
TK_Src_SrcA_SRC_Y	Q93052	LPP	P12931	SRC	Y297	Y297C	297	Missense	central	0	yes	22.001	0.000	EPSD	COSMIC	20.673	Loss
TK_Src_SrcA_SRC_Y	Q93052	LPP	P12931	SRC	Y297	R295L	295	Missense	proximal	-2	no	22.001	22.002	EPSD	COSMIC	20.673	Up-regulation
TK_Src_SrcA_SRC_Y	Q93052	LPP	P12931	SRC	Y297	Q293L	293	Missense	distal	-4	no	22.001	21.422	EPSD	COSMIC	20.673	Down-regulation
TK_Src_SrcA_SRC_Y	Q93052	LPP	P12931	SRC	Y297	R295H	295	Missense	proximal	-2	no	22.001	22.867	EPSD	COSMIC	20.673	Up-regulation
TK_Src_SrcA_SRC_Y	Q93052	LPP	P12931	SRC	Y301	Y297C	297	Missense	distal	-4	no	22.380	21.097	EPSD;PhosphoSitePlus	COSMIC	20.673	Down-regulation
TK_Src_SrcA_SRC_Y	Q93052	LPP	P12931	SRC	Y301	P305S	305	Missense	distal	4	no	22.380	22.401	EPSD;PhosphoSitePlus	COSMIC	20.673	Up-regulation
TK_Src_SrcA_SRC_Y	Q93052	LPP	P12931	SRC	Y301	R295L	295	Missense	distal	-6	no	22.380	22.451	EPSD;PhosphoSitePlus	COSMIC	20.673	Up-regulation
TK_Src_SrcA_SRC_Y	Q93052	LPP	P12931	SRC	Y301	R295H	295	Missense	distal	-6	no	22.380	22.347	EPSD;PhosphoSitePlus	COSMIC	20.673	Down-regulation
TK_Src_SrcA_SRC_Y	Q93052	LPP	P12931	SRC	Y317	Q319H	319	Missense	proximal	2	no	23.340	22.838	EPSD	COSMIC	20.673	Down-regulation
TK_Src_SrcA_SRC_Y	Q93052	LPP	P12931	SRC	Y317	P315S	315	Missense	proximal	-2	no	23.340	22.554	EPSD	COSMIC	20.673	Down-regulation
TK_Src_SrcA_SRC_Y	Q93052	LPP	P12931	SRC	Y332	P334L	334	Missense	proximal	2	no	20.717	20.260	EPSD	COSMIC	20.673	Loss
TK_Src_SrcA_SRC_Y	P04439	HLA-A	P12931	SRC	Y344	T345S	345	Missense	proximal	1	no	20.913	21.567	PhosphoSitePlus	COSMIC	20.673	Up-regulation
TK_Src_SrcA_SRC_Y	P04439	HLA-A	P12931	SRC	Y344	Q346K	346	Missense	proximal	2	no	20.913	20.052	PhosphoSitePlus	COSMIC	20.673	Loss
TK_Src_SrcA_SRC_Y	P04439	HLA-A	P12931	SRC	Y344	D338V	338	Missense	distal	-6	no	20.913	20.499	PhosphoSitePlus	COSMIC;GDSC	20.673	Loss
TK_Src_SrcA_SRC_Y	P04439	HLA-A	P12931	SRC	Y344	T345I	345	Missense	proximal	1	no	20.913	20.123	PhosphoSitePlus	COSMIC	20.673	Loss
TK_Src_SrcA_SRC_Y	P53355	DAPK1	P12931	SRC	Y12	Y13H	13	Missense	proximal	1	no	21.097	20.050	EPSD	COSMIC	20.673	Loss
TK_Src_SrcA_SRC_Y	P53355	DAPK1	P12931	SRC	Y13	G20D	20	Missense	distal	7	no	22.105	22.043	EPSD	COSMIC;GDSC;CCLE	20.673	Down-regulation
TK_Src_SrcA_SRC_Y	P53355	DAPK1	P12931	SRC	Y13	Y13H	13	Missense	central	0	yes	22.105	0.000	EPSD	COSMIC	20.673	Loss
TK_Src_SrcA_SRC_Y	O15492	RGS16	P12931	SRC	Y168	T161I	161	Missense	distal	-7	no	21.869	21.517	EPSD;PhosphoSitePlus	COSMIC	20.673	Down-regulation
TK_Src_SrcA_SRC_Y	Q9Y371	SH3GLB1	P12931	SRC	Y80	E76Q	76	Missense	distal	-4	no	23.958	23.128	PhosphoSitePlus	COSMIC	20.673	Down-regulation
TK_Src_SrcA_SRC_Y	Q9UPT8	ZC3H4	P12931	SRC	Y190	S189N	189	Missense	proximal	-1	no	21.179	20.243	EPSD	COSMIC	20.673	Loss
TK_Src_SrcA_SRC_Y	Q9UPT8	ZC3H4	P12931	SRC	Y193	S189N	189	Missense	distal	-4	no	21.031	21.445	EPSD	COSMIC	20.673	Up-regulation
TK_Src_SrcA_SRC_Y	Q9UPT8	ZC3H4	P12931	SRC	Y196	S189N	189	Missense	distal	-7	no	23.086	23.054	EPSD	COSMIC	20.673	Down-regulation
TK_Src_SrcA_SRC_Y	Q9UPT8	ZC3H4	P12931	SRC	Y217	Y217D	217	Missense	central	0	yes	23.941	0.000	EPSD	COSMIC;GDSC;CCLE	20.673	Loss
TK_Src_SrcA_SRC_Y	Q9UPT8	ZC3H4	P12931	SRC	Y364	Y364C	364	Missense	central	0	yes	22.518	0.000	EPSD	COSMIC	20.673	Loss
TK_Src_SrcA_SRC_Y	Q9UPT8	ZC3H4	P12931	SRC	Y1218	T1212M	1212	Missense	distal	-6	no	22.748	22.260	EPSD;PhosphoSitePlus	COSMIC	20.673	Down-regulation
TK_Src_SrcA_SRC_Y	Q9UPT8	ZC3H4	P12931	SRC	Y1218	R1220W	1220	Missense	proximal	2	no	22.748	23.105	EPSD;PhosphoSitePlus	COSMIC	20.673	Up-regulation
TK_Src_SrcA_SRC_Y	Q9NWQ8	PAG1	P12931	SRC	Y163	S170F	170	Missense	distal	7	no	20.831	20.859	EPSD	COSMIC	20.673	Up-regulation
TK_Src_SrcA_SRC_Y	Q9NWQ8	PAG1	P12931	SRC	Y163	E164A	164	Missense	proximal	1	no	20.831	19.534	EPSD	COSMIC	20.673	Loss
TK_Src_SrcA_SRC_Y	Q9NWQ8	PAG1	P12931	SRC	Y181	E186K	186	Missense	distal	5	no	22.670	22.703	EPSD	COSMIC	20.673	Up-regulation
TK_Src_SrcA_SRC_Y	Q9NWQ8	PAG1	P12931	SRC	Y417	V411I	411	Missense	distal	-6	no	21.965	22.192	EPSD	COSMIC;GDSC	20.673	Up-regulation
TK_Src_SrcA_SRC_Y	Q9NWQ8	PAG1	P12931	SRC	Y417	S421R	421	Missense	distal	4	no	21.965	21.938	EPSD	COSMIC	20.673	Down-regulation
TK_Src_SrcA_SRC_Y	Q9NWQ8	PAG1	P12931	SRC	Y417	P412S	412	Missense	distal	-5	no	21.965	22.067	EPSD	COSMIC	20.673	Up-regulation
TK_Src_SrcA_SRC_Y	Q16832	DDR2	P12931	SRC	Y471	R473C	473	Missense	proximal	2	no	21.934	21.334	EPSD;PhosphoSitePlus	COSMIC	20.673	Down-regulation
TK_Src_SrcA_SRC_Y	Q16832	DDR2	P12931	SRC	Y471	S467F	467	Missense	distal	-4	no	21.934	21.016	EPSD;PhosphoSitePlus	COSMIC	20.673	Down-regulation
TK_Src_SrcA_SRC_Y	Q16832	DDR2	P12931	SRC	Y471	I474M	474	Missense	distal	3	no	21.934	21.628	EPSD;PhosphoSitePlus	COSMIC	20.673	Down-regulation
TK_Src_SrcA_SRC_Y	Q16832	DDR2	P12931	SRC	Y471	I474T	474	Missense	distal	3	no	21.934	21.468	EPSD;PhosphoSitePlus	COSMIC	20.673	Down-regulation
TK_Src_SrcA_SRC_Y	Q16832	DDR2	P12931	SRC	Y471	D472Y	472	Missense	proximal	1	no	21.934	21.536	EPSD;PhosphoSitePlus	COSMIC	20.673	Down-regulation
TK_Src_SrcA_SRC_Y	Q16832	DDR2	P12931	SRC	Y471	Y471D	471	Missense	central	0	yes	21.934	0.000	EPSD;PhosphoSitePlus	COSMIC	20.673	Loss
TK_Src_SrcA_SRC_Y	Q16832	DDR2	P12931	SRC	Y471	G466R	466	Missense	distal	-5	no	21.934	21.919	EPSD;PhosphoSitePlus	COSMIC	20.673	Down-regulation
TK_Src_SrcA_SRC_Y	Q16832	DDR2	P12931	SRC	Y481	I488M	488	Missense	distal	7	no	21.232	21.259	EPSD	COSMIC	20.673	Up-regulation
TK_Src_SrcA_SRC_Y	Q16832	DDR2	P12931	SRC	Y481	I474M	474	Missense	distal	-7	no	21.232	20.947	EPSD	COSMIC	20.673	Down-regulation
TK_Src_SrcA_SRC_Y	Q16832	DDR2	P12931	SRC	Y481	I474T	474	Missense	distal	-7	no	21.232	21.584	EPSD	COSMIC	20.673	Up-regulation
TK_Src_SrcA_SRC_Y	Q16832	DDR2	P12931	SRC	Y481	S485C	485	Missense	distal	4	no	21.232	21.207	EPSD	COSMIC	20.673	Down-regulation
TK_Src_SrcA_SRC_Y	Q16832	DDR2	P12931	SRC	Y481	P484S	484	Missense	distal	3	no	21.232	20.494	EPSD	COSMIC	20.673	Loss
TK_Src_SrcA_SRC_Y	Q16832	DDR2	P12931	SRC	Y521	V518L	518	Missense	distal	-3	no	20.680	19.869	EPSD	COSMIC	20.673	Loss
TK_Src_SrcA_SRC_Y	Q16832	DDR2	P12931	SRC	Y521	P519H	519	Missense	proximal	-2	no	20.680	20.015	EPSD	COSMIC;GDSC;CCLE	20.673	Loss
TK_Src_SrcA_SRC_Y	Q16832	DDR2	P12931	SRC	Y521	E523V	523	Missense	proximal	2	no	20.680	20.712	EPSD	COSMIC	20.673	Up-regulation
TK_Src_SrcA_SRC_Y	Q16832	DDR2	P12931	SRC	Y521	Y521S	521	Missense	central	0	yes	20.680	0.000	EPSD	COSMIC	20.673	Loss
TK_Src_SrcA_SRC_Y	Q16832	DDR2	P12931	SRC	Y521	A522S	522	Missense	proximal	1	no	20.680	20.880	EPSD	COSMIC	20.673	Up-regulation
TK_Src_SrcA_SRC_Y	Q16832	DDR2	P12931	SRC	Y521	E523K	523	Missense	proximal	2	no	20.680	19.510	EPSD	COSMIC	20.673	Loss
TK_Src_SrcA_SRC_Y	Q16832	DDR2	P12931	SRC	Y740	G745C	745	Missense	distal	5	no	22.905	23.158	EPSD;PhosphoSitePlus	COSMIC	20.673	Up-regulation
TK_Src_SrcA_SRC_Y	Q16832	DDR2	P12931	SRC	Y740	N734D	734	Missense	distal	-6	no	22.905	23.096	EPSD;PhosphoSitePlus	COSMIC	20.673	Up-regulation
TK_Src_SrcA_SRC_Y	Q16832	DDR2	P12931	SRC	Y740	S737C	737	Missense	distal	-3	no	22.905	20.184	EPSD;PhosphoSitePlus	COSMIC	20.673	Loss
TK_Src_SrcA_SRC_Y	Q16832	DDR2	P12931	SRC	Y741	N734D	734	Missense	distal	-7	no	21.636	21.717	EPSD;PhosphoSitePlus	COSMIC	20.673	Up-regulation
TK_Src_SrcA_SRC_Y	Q16832	DDR2	P12931	SRC	Y741	S737C	737	Missense	distal	-4	no	21.636	20.307	EPSD;PhosphoSitePlus	COSMIC	20.673	Loss
TK_Src_SrcA_SRC_Y	Q8N556	AFAP1	P12931	SRC	Y93	L89I	89	Missense	distal	-4	no	22.341	21.904	EPSD;PhosphoSitePlus	COSMIC;GDSC;CCLE	20.673	Down-regulation
TK_Src_SrcA_SRC_Y	Q8N556	AFAP1	P12931	SRC	Y93	P90S	90	Missense	distal	-3	no	22.341	23.459	EPSD;PhosphoSitePlus	COSMIC	20.673	Up-regulation
TK_Src_SrcA_SRC_Y	Q8N556	AFAP1	P12931	SRC	Y93	A97V	97	Missense	distal	4	no	22.341	22.315	EPSD;PhosphoSitePlus	COSMIC	20.673	Down-regulation
TK_Src_SrcA_SRC_Y	Q8N556	AFAP1	P12931	SRC	Y94	L89I	89	Missense	distal	-5	no	25.289	25.242	EPSD;PhosphoSitePlus	COSMIC;GDSC;CCLE	20.673	Down-regulation
TK_Src_SrcA_SRC_Y	Q8N556	AFAP1	P12931	SRC	Y94	P90S	90	Missense	distal	-4	no	25.289	25.342	EPSD;PhosphoSitePlus	COSMIC	20.673	Up-regulation
TK_Src_SrcA_SRC_Y	Q8N556	AFAP1	P12931	SRC	Y94	A97V	97	Missense	distal	3	no	25.289	25.859	EPSD;PhosphoSitePlus	COSMIC	20.673	Up-regulation
TK_Src_SrcA_SRC_Y	Q8N556	AFAP1	P12931	SRC	Y122	S124P	124	Missense	proximal	2	no	21.756	21.149	EPSD	COSMIC	20.673	Down-regulation
TK_Src_SrcA_SRC_Y	Q8N556	AFAP1	P12931	SRC	Y125	S124P	124	Missense	proximal	-1	no	21.006	21.357	EPSD;PhosphoSitePlus	COSMIC	20.673	Up-regulation
TK_Src_SrcA_SRC_Y	Q8N556	AFAP1	P12931	SRC	Y451	P446L	446	Missense	distal	-5	no	22.849	22.693	EPSD;PhosphoSitePlus	COSMIC;CCLE	20.673	Down-regulation
TK_Src_SrcA_SRC_Y	Q8N556	AFAP1	P12931	SRC	Y501	D503V	503	Missense	proximal	2	no	21.075	21.394	EPSD	COSMIC	20.673	Up-regulation
TK_Src_SrcA_SRC_Y	Q8N556	AFAP1	P12931	SRC	Y501	P505Q	505	Missense	distal	4	no	21.075	21.092	EPSD	COSMIC	20.673	Up-regulation
TK_Src_SrcA_SRC_Y	Q96RI1	NR1H4	P12931	SRC	Y77	S73L	73	Missense	distal	-4	no	22.496	21.808	PhosphoSitePlus	COSMIC	20.673	Down-regulation
TK_Src_SrcA_SRC_Y	Q13322	GRB10	P12931	SRC	Y16	P14A	14	Missense	proximal	-2	no	20.861	19.709	EPSD	COSMIC	20.673	Loss
TK_Src_SrcA_SRC_Y	Q13322	GRB10	P12931	SRC	Y16	K19R	19	Missense	distal	3	no	20.861	21.192	EPSD	COSMIC	20.673	Up-regulation
TK_Src_SrcA_SRC_Y	Q13322	GRB10	P12931	SRC	Y16	K19N	19	Missense	distal	3	no	20.861	23.179	EPSD	COSMIC	20.673	Up-regulation
TK_Src_SrcA_SRC_Y	Q13322	GRB10	P12931	SRC	Y16	D18E	18	Missense	proximal	2	no	20.861	21.149	EPSD	COSMIC	20.673	Up-regulation
TK_Src_SrcA_SRC_Y	Q13322	GRB10	P12931	SRC	Y67	A61V	61	Missense	distal	-6	no	21.316	21.155	PhosphoSitePlus	COSMIC	20.673	Down-regulation
TK_Src_SrcA_SRC_Y	Q13322	GRB10	P12931	SRC	Y67	S62L	62	Missense	distal	-5	no	21.316	21.057	PhosphoSitePlus	COSMIC	20.673	Down-regulation
TK_Src_SrcA_SRC_Y	Q13322	GRB10	P12931	SRC	Y67	S68L	68	Missense	proximal	1	no	21.316	19.770	PhosphoSitePlus	COSMIC	20.673	Loss
TK_Src_SrcA_SRC_Y	Q13322	GRB10	P12931	SRC	Y67	M72R	72	Missense	distal	5	no	21.316	20.949	PhosphoSitePlus	COSMIC	20.673	Down-regulation
TK_Src_SrcA_SRC_Y	Q13322	GRB10	P12931	SRC	Y67	A69P	69	Missense	proximal	2	no	21.316	21.061	PhosphoSitePlus	COSMIC	20.673	Down-regulation
TK_Src_SrcA_SRC_Y	Q13435	SF3B2	P12931	SRC	Y591	L584P	584	Missense	distal	-7	no	23.212	23.327	EPSD	COSMIC	20.673	Up-regulation
TK_Src_SrcA_SRC_Y	Q13435	SF3B2	P12931	SRC	Y591	F597S	597	Missense	distal	6	no	23.212	23.181	EPSD	COSMIC	20.673	Down-regulation
TK_Src_SrcA_SRC_Y	Q13435	SF3B2	P12931	SRC	Y645	P641H	641	Missense	distal	-4	no	20.833	20.672	EPSD	COSMIC	20.673	Loss
TK_Src_SrcA_SRC_Y	Q13435	SF3B2	P12931	SRC	Y645	S644W	644	Missense	proximal	-1	no	20.833	19.779	EPSD	COSMIC	20.673	Loss
TK_Src_SrcA_SRC_Y	Q13435	SF3B2	P12931	SRC	Y806	S802L	802	Missense	distal	-4	no	21.090	20.403	EPSD	COSMIC	20.673	Loss
TK_Src_SrcA_SRC_Y	Q13435	SF3B2	P12931	SRC	Y806	Y806N	806	Missense	central	0	yes	21.090	0.000	EPSD	COSMIC	20.673	Loss
TK_Src_SrcA_SRC_Y	Q9NYF8	BCLAF1	P12931	SRC	Y81	G75C	75	Missense	distal	-6	no	22.817	22.423	EPSD;PhosphoSitePlus	COSMIC	20.673	Down-regulation
TK_Src_SrcA_SRC_Y	Q9NYF8	BCLAF1	P12931	SRC	Y81	G77W	77	Missense	distal	-4	no	22.817	21.427	EPSD;PhosphoSitePlus	COSMIC	20.673	Down-regulation
TK_Src_SrcA_SRC_Y	Q9NYF8	BCLAF1	P12931	SRC	Y81	G84S	84	Missense	distal	3	no	22.817	22.580	EPSD;PhosphoSitePlus	COSMIC	20.673	Down-regulation
TK_Src_SrcA_SRC_Y	Q9NYF8	BCLAF1	P12931	SRC	Y81	G86S	86	Missense	distal	5	no	22.817	22.611	EPSD;PhosphoSitePlus	COSMIC;GDSC	20.673	Down-regulation
TK_Src_SrcA_SRC_Y	Q9NYF8	BCLAF1	P12931	SRC	Y81	Q82E	82	Missense	proximal	1	no	22.817	23.802	EPSD;PhosphoSitePlus	COSMIC	20.673	Up-regulation
TK_Src_SrcA_SRC_Y	Q9NYF8	BCLAF1	P12931	SRC	Y81	Y81C	81	Missense	central	0	yes	22.817	0.000	EPSD;PhosphoSitePlus	COSMIC	20.673	Loss
TK_Src_SrcA_SRC_Y	Q9NYF8	BCLAF1	P12931	SRC	Y150	P149S	149	Missense	proximal	-1	no	21.992	21.641	EPSD;PhosphoSitePlus	COSMIC	20.673	Down-regulation
TK_Src_SrcA_SRC_Y	Q9NYF8	BCLAF1	P12931	SRC	Y150	P154S	154	Missense	distal	4	no	21.992	22.014	EPSD;PhosphoSitePlus	COSMIC	20.673	Up-regulation
TK_Src_SrcA_SRC_Y	Q9NYF8	BCLAF1	P12931	SRC	Y150	Y150C	150	Missense	central	0	yes	21.992	0.000	EPSD;PhosphoSitePlus	COSMIC	20.673	Loss
TK_Src_SrcA_SRC_Y	Q9NYF8	BCLAF1	P12931	SRC	Y150	R145H	145	Missense	distal	-5	no	21.992	22.201	EPSD;PhosphoSitePlus	COSMIC	20.673	Up-regulation
TK_Src_SrcA_SRC_Y	Q9NYF8	BCLAF1	P12931	SRC	Y150	S156Y	156	Missense	distal	6	no	21.992	22.026	EPSD;PhosphoSitePlus	COSMIC	20.673	Up-regulation
TK_Src_SrcA_SRC_Y	Q9NYF8	BCLAF1	P12931	SRC	Y150	Y150N	150	Missense	central	0	yes	21.992	0.000	EPSD;PhosphoSitePlus	COSMIC	20.673	Loss
TK_Src_SrcA_SRC_Y	Q9NYF8	BCLAF1	P12931	SRC	Y150	S148T	148	Missense	proximal	-2	no	21.992	21.754	EPSD;PhosphoSitePlus	COSMIC	20.673	Down-regulation
TK_Src_SrcA_SRC_Y	Q9NYF8	BCLAF1	P12931	SRC	Y284	S282G	282	Missense	proximal	-2	no	20.774	21.386	EPSD;PhosphoSitePlus	COSMIC	20.673	Up-regulation
TK_Src_SrcA_SRC_Y	Q9NYF8	BCLAF1	P12931	SRC	Y284	G278V	278	Missense	distal	-6	no	20.774	20.667	EPSD;PhosphoSitePlus	COSMIC	20.673	Loss
TK_Src_SrcA_SRC_Y	Q9NYF8	BCLAF1	P12931	SRC	Y284	G278E	278	Missense	distal	-6	no	20.774	21.003	EPSD;PhosphoSitePlus	COSMIC	20.673	Up-regulation
TK_Src_SrcA_SRC_Y	Q9NYF8	BCLAF1	P12931	SRC	Y284	P291L	291	Missense	distal	7	no	20.774	20.768	EPSD;PhosphoSitePlus	COSMIC	20.673	Down-regulation
TK_Src_SrcA_SRC_Y	Q9NYF8	BCLAF1	P12931	SRC	Y408	E404D	404	Missense	distal	-4	no	21.959	22.184	EPSD;PhosphoSitePlus	COSMIC	20.673	Up-regulation
TK_Src_SrcA_SRC_Y	Q9NYF8	BCLAF1	P12931	SRC	Y408	D407N	407	Missense	proximal	-1	no	21.959	21.009	EPSD;PhosphoSitePlus	COSMIC	20.673	Down-regulation
TK_Src_SrcA_SRC_Y	Q9NYF8	BCLAF1	P12931	SRC	Y408	R409T	409	Missense	proximal	1	no	21.959	22.184	EPSD;PhosphoSitePlus	COSMIC	20.673	Up-regulation
TK_Src_SrcA_SRC_Y	Q9NYF8	BCLAF1	P12931	SRC	Y408	R409K	409	Missense	proximal	1	no	21.959	21.541	EPSD;PhosphoSitePlus	COSMIC	20.673	Down-regulation
TK_Src_SrcA_SRC_Y	Q9NYF8	BCLAF1	P12931	SRC	Y408	E406D	406	Missense	proximal	-2	no	21.959	21.671	EPSD;PhosphoSitePlus	COSMIC	20.673	Down-regulation
TK_Src_SrcA_SRC_Y	Q9NYF8	BCLAF1	P12931	SRC	Y408	T405K	405	Missense	distal	-3	no	21.959	21.381	EPSD;PhosphoSitePlus	COSMIC	20.673	Down-regulation
TK_Src_SrcA_SRC_Y	Q9NYF8	BCLAF1	P12931	SRC	Y408	F411L	411	Missense	distal	3	no	21.959	21.718	EPSD;PhosphoSitePlus	COSMIC	20.673	Down-regulation
TK_Src_SrcA_SRC_Y	Q9NYF8	BCLAF1	P12931	SRC	Y408	T402A	402	Missense	distal	-6	no	21.959	21.921	EPSD;PhosphoSitePlus	COSMIC	20.673	Down-regulation
TK_Src_SrcA_SRC_Y	Q9NYF8	BCLAF1	P12931	SRC	Y408	Q410L	410	Missense	proximal	2	no	21.959	21.377	EPSD;PhosphoSitePlus	COSMIC	20.673	Down-regulation
TK_Src_SrcA_SRC_Y	Q9NYF8	BCLAF1	P12931	SRC	Y408	S414F	414	Missense	distal	6	no	21.959	21.990	EPSD;PhosphoSitePlus	COSMIC	20.673	Up-regulation
TK_Src_SrcA_SRC_Y	Q9NYF8	BCLAF1	P12931	SRC	Y892	K891Q	891	Missense	proximal	-1	no	19.414	20.917	EPSD	COSMIC	20.673	Gain
TK_Src_SrcA_SRC_Y	O15530	PDPK1	P12931	SRC	Y9	V12M	12	Missense	distal	3	no	21.814	21.448	EPSD	COSMIC	20.673	Down-regulation
TK_Src_SrcA_SRC_Y	O15530	PDPK1	P12931	SRC	Y9	R3G	3	Missense	distal	-6	no	21.814	21.811	EPSD	COSMIC	20.673	Down-regulation
TK_Src_SrcA_SRC_Y	O15530	PDPK1	P12931	SRC	Y248	Y248H	248	Missense	central	0	yes	22.781	0.000	EPSD	COSMIC	20.673	Loss
TK_Src_SrcA_SRC_Y	O15530	PDPK1	P12931	SRC	Y373	N378I	378	Missense	distal	5	no	23.167	23.315	EPSD;PhosphoSitePlus	COSMIC	20.673	Up-regulation
TK_Src_SrcA_SRC_Y	O15530	PDPK1	P12931	SRC	Y376	S381N	381	Missense	distal	5	no	21.887	21.886	PhosphoSitePlus;EPSD	COSMIC	20.673	Down-regulation
TK_Src_SrcA_SRC_Y	O15530	PDPK1	P12931	SRC	Y376	N378I	378	Missense	proximal	2	no	21.887	20.797	PhosphoSitePlus;EPSD	COSMIC	20.673	Down-regulation
TK_Src_SrcA_SRC_Y	O15530	PDPK1	P12931	SRC	Y485	E480A	480	Missense	distal	-5	no	21.125	20.842	EPSD	COSMIC	20.673	Down-regulation
TK_Src_SrcA_SRC_Y	O15530	PDPK1	P12931	SRC	Y485	E480Q	480	Missense	distal	-5	no	21.125	20.698	EPSD	COSMIC	20.673	Down-regulation
TK_Src_SrcA_SRC_Y	O15530	PDPK1	P12931	SRC	Y485	G481V	481	Missense	distal	-4	no	21.125	20.309	EPSD	COSMIC	20.673	Loss
TK_Src_SrcA_SRC_Y	O15530	PDPK1	P12931	SRC	Y486	E480A	480	Missense	distal	-6	no	21.574	21.398	EPSD	COSMIC	20.673	Down-regulation
TK_Src_SrcA_SRC_Y	O15530	PDPK1	P12931	SRC	Y486	E480Q	480	Missense	distal	-6	no	21.574	21.450	EPSD	COSMIC	20.673	Down-regulation
TK_Src_SrcA_SRC_Y	O15530	PDPK1	P12931	SRC	Y486	G481V	481	Missense	distal	-5	no	21.574	21.545	EPSD	COSMIC	20.673	Down-regulation
TK_Src_SrcA_SRC_Y	Q15654	TRIP6	P12931	SRC	Y55	P48L	48	Missense	distal	-7	no	23.771	23.656	PhosphoSitePlus	COSMIC	20.673	Down-regulation
TK_Src_SrcA_SRC_Y	Q15654	TRIP6	P12931	SRC	Y123	P127S	127	Missense	distal	4	no	23.813	23.835	EPSD	COSMIC	20.673	Up-regulation
TK_Src_SrcA_SRC_Y	Q15654	TRIP6	P12931	SRC	Y123	P129S	129	Missense	distal	6	no	23.813	23.797	EPSD	COSMIC	20.673	Down-regulation
TK_Src_SrcA_SRC_Y	Q15654	TRIP6	P12931	SRC	Y320	F319L	319	Missense	proximal	-1	no	20.597	21.456	EPSD	COSMIC	20.673	Gain
TK_Src_SrcA_SRC_Y	Q9Y613	FHOD1	P12931	SRC	Y176	H174L	174	Missense	proximal	-2	no	20.923	20.058	EPSD	COSMIC	20.673	Loss
TK_Src_SrcA_SRC_Y	Q9Y613	FHOD1	P12931	SRC	Y439	A441T	441	Missense	proximal	2	no	20.937	21.030	EPSD	COSMIC;GDSC	20.673	Up-regulation
TK_Src_SrcA_SRC_Y	Q9Y613	FHOD1	P12931	SRC	Y439	R442Q	442	Missense	distal	3	no	20.937	21.349	EPSD	COSMIC;GDSC;CCLE	20.673	Up-regulation
TK_Src_SrcA_SRC_Y	Q9Y613	FHOD1	P12931	SRC	Y439	N446T	446	Missense	distal	7	no	20.937	20.939	EPSD	COSMIC	20.673	Up-regulation
TK_Src_SrcA_SRC_Y	Q9Y613	FHOD1	P12931	SRC	Y439	Y439C	439	Missense	central	0	yes	20.937	0.000	EPSD	COSMIC	20.673	Loss
TK_Src_SrcA_SRC_Y	Q9Y613	FHOD1	P12931	SRC	Y878	P882S	882	Missense	distal	4	no	23.528	23.550	EPSD	COSMIC	20.673	Up-regulation
TK_Src_SrcA_SRC_Y	Q9Y613	FHOD1	P12931	SRC	Y878	R871Q	871	Missense	distal	-7	no	23.528	23.304	EPSD	COSMIC	20.673	Down-regulation
TK_Src_SrcA_SRC_Y	Q9Y613	FHOD1	P12931	SRC	Y878	P882H	882	Missense	distal	4	no	23.528	23.537	EPSD	COSMIC	20.673	Up-regulation
TK_Src_SrcA_SRC_Y	P00533	EGFR	P12931	SRC	Y112	G109E	109	Missense	distal	-3	no	22.347	22.951	EPSD	COSMIC	20.673	Up-regulation
TK_Src_SrcA_SRC_Y	P00533	EGFR	P12931	SRC	Y112	A118V	118	Missense	distal	6	no	22.347	22.357	EPSD	COSMIC	20.673	Up-regulation
TK_Src_SrcA_SRC_Y	P00533	EGFR	P12931	SRC	Y112	Q105H	105	Missense	distal	-7	no	22.347	22.277	EPSD	COSMIC	20.673	Down-regulation
TK_Src_SrcA_SRC_Y	P00533	EGFR	P12931	SRC	Y112	N115T	115	Missense	distal	3	no	22.347	21.496	EPSD	COSMIC	20.673	Down-regulation
TK_Src_SrcA_SRC_Y	P00533	EGFR	P12931	SRC	Y112	A118S	118	Missense	distal	6	no	22.347	22.343	EPSD	COSMIC	20.673	Down-regulation
TK_Src_SrcA_SRC_Y	P00533	EGFR	P12931	SRC	Y112	M111T	111	Missense	proximal	-1	no	22.347	22.600	EPSD	COSMIC	20.673	Up-regulation
TK_Src_SrcA_SRC_Y	P00533	EGFR	P12931	SRC	Y112	I106F	106	Missense	distal	-6	no	22.347	22.234	EPSD	COSMIC	20.673	Down-regulation
TK_Src_SrcA_SRC_Y	P00533	EGFR	P12931	SRC	Y112	E114G	114	Missense	proximal	2	no	22.347	21.393	EPSD	COSMIC	20.673	Down-regulation
TK_Src_SrcA_SRC_Y	P00533	EGFR	P12931	SRC	Y112	L119S	119	Missense	distal	7	no	22.347	22.334	EPSD	COSMIC	20.673	Down-regulation
TK_Src_SrcA_SRC_Y	P00533	EGFR	P12931	SRC	Y112	A118T	118	Missense	distal	6	no	22.347	22.334	EPSD	COSMIC	20.673	Down-regulation
TK_Src_SrcA_SRC_Y	P00533	EGFR	P12931	SRC	Y112	Y113H	113	Missense	proximal	1	no	22.347	21.301	EPSD	COSMIC	20.673	Down-regulation
TK_Src_SrcA_SRC_Y	P00533	EGFR	P12931	SRC	Y112	G109A	109	Missense	distal	-3	no	22.347	21.623	EPSD	COSMIC	20.673	Down-regulation
TK_Src_SrcA_SRC_Y	P00533	EGFR	P12931	SRC	Y113	G109E	109	Missense	distal	-4	no	21.380	21.813	EPSD	COSMIC	20.673	Up-regulation
TK_Src_SrcA_SRC_Y	P00533	EGFR	P12931	SRC	Y113	A118V	118	Missense	distal	5	no	21.380	21.522	EPSD	COSMIC	20.673	Up-regulation
TK_Src_SrcA_SRC_Y	P00533	EGFR	P12931	SRC	Y113	N115T	115	Missense	proximal	2	no	21.380	21.369	EPSD	COSMIC	20.673	Down-regulation
TK_Src_SrcA_SRC_Y	P00533	EGFR	P12931	SRC	Y113	A118S	118	Missense	distal	5	no	21.380	21.425	EPSD	COSMIC	20.673	Up-regulation
TK_Src_SrcA_SRC_Y	P00533	EGFR	P12931	SRC	Y113	M111T	111	Missense	proximal	-2	no	21.380	22.478	EPSD	COSMIC	20.673	Up-regulation
TK_Src_SrcA_SRC_Y	P00533	EGFR	P12931	SRC	Y113	I106F	106	Missense	distal	-7	no	21.380	21.303	EPSD	COSMIC	20.673	Down-regulation
TK_Src_SrcA_SRC_Y	P00533	EGFR	P12931	SRC	Y113	E114G	114	Missense	proximal	1	no	21.380	20.397	EPSD	COSMIC	20.673	Loss
TK_Src_SrcA_SRC_Y	P00533	EGFR	P12931	SRC	Y113	L119S	119	Missense	distal	6	no	21.380	21.348	EPSD	COSMIC	20.673	Down-regulation
TK_Src_SrcA_SRC_Y	P00533	EGFR	P12931	SRC	Y113	A118T	118	Missense	distal	5	no	21.380	21.595	EPSD	COSMIC	20.673	Up-regulation
TK_Src_SrcA_SRC_Y	P00533	EGFR	P12931	SRC	Y113	Y113H	113	Missense	central	0	yes	21.380	0.000	EPSD	COSMIC	20.673	Loss
TK_Src_SrcA_SRC_Y	P00533	EGFR	P12931	SRC	Y113	G109A	109	Missense	distal	-4	no	21.380	20.697	EPSD	COSMIC	20.673	Down-regulation
TK_Src_SrcA_SRC_Y	P00533	EGFR	P12931	SRC	Y764	V769M	769	Missense	distal	5	no	23.344	23.638	EPSD;PhosphoSitePlus	COSMIC	20.673	Up-regulation
TK_Src_SrcA_SRC_Y	P00533	EGFR	P12931	SRC	Y764	S768G	768	Missense	distal	4	no	23.344	23.319	EPSD;PhosphoSitePlus	COSMIC	20.673	Down-regulation
TK_Src_SrcA_SRC_Y	P00533	EGFR	P12931	SRC	Y764	D761N	761	Missense	distal	-3	no	23.344	22.835	EPSD;PhosphoSitePlus	COSMIC	20.673	Down-regulation
TK_Src_SrcA_SRC_Y	P00533	EGFR	P12931	SRC	Y764	Y764S	764	Missense	central	0	yes	23.344	0.000	EPSD;PhosphoSitePlus	COSMIC	20.673	Loss
TK_Src_SrcA_SRC_Y	P00533	EGFR	P12931	SRC	Y764	D770N	770	Missense	distal	6	no	23.344	23.347	EPSD;PhosphoSitePlus	COSMIC	20.673	Up-regulation
TK_Src_SrcA_SRC_Y	P00533	EGFR	P12931	SRC	Y764	I759V	759	Missense	distal	-5	no	23.344	23.552	EPSD;PhosphoSitePlus	COSMIC	20.673	Up-regulation
TK_Src_SrcA_SRC_Y	P00533	EGFR	P12931	SRC	Y764	D761G	761	Missense	distal	-3	no	23.344	22.695	EPSD;PhosphoSitePlus	COSMIC	20.673	Down-regulation
TK_Src_SrcA_SRC_Y	P00533	EGFR	P12931	SRC	Y764	A767V	767	Missense	distal	3	no	23.344	23.914	EPSD;PhosphoSitePlus	COSMIC	20.673	Up-regulation
TK_Src_SrcA_SRC_Y	P00533	EGFR	P12931	SRC	Y764	E758G	758	Missense	distal	-6	no	23.344	23.114	EPSD;PhosphoSitePlus	COSMIC	20.673	Down-regulation
TK_Src_SrcA_SRC_Y	P00533	EGFR	P12931	SRC	Y764	K757N	757	Missense	distal	-7	no	23.344	23.398	EPSD;PhosphoSitePlus	COSMIC	20.673	Up-regulation
TK_Src_SrcA_SRC_Y	P00533	EGFR	P12931	SRC	Y764	V765E	765	Missense	proximal	1	no	23.344	25.225	EPSD;PhosphoSitePlus	COSMIC	20.673	Up-regulation
TK_Src_SrcA_SRC_Y	P00533	EGFR	P12931	SRC	Y764	S768N	768	Missense	distal	4	no	23.344	23.375	EPSD;PhosphoSitePlus	COSMIC	20.673	Up-regulation
TK_Src_SrcA_SRC_Y	P00533	EGFR	P12931	SRC	Y764	A763V	763	Missense	proximal	-1	no	23.344	24.680	EPSD;PhosphoSitePlus	COSMIC	20.673	Up-regulation
TK_Src_SrcA_SRC_Y	P00533	EGFR	P12931	SRC	Y764	V765M	765	Missense	proximal	1	no	23.344	22.720	EPSD;PhosphoSitePlus	COSMIC	20.673	Down-regulation
TK_Src_SrcA_SRC_Y	P00533	EGFR	P12931	SRC	Y764	S768C	768	Missense	distal	4	no	23.344	23.319	EPSD;PhosphoSitePlus	COSMIC	20.673	Down-regulation
TK_Src_SrcA_SRC_Y	P00533	EGFR	P12931	SRC	Y764	A763D	763	Missense	proximal	-1	no	23.344	23.246	EPSD;PhosphoSitePlus	COSMIC	20.673	Down-regulation
TK_Src_SrcA_SRC_Y	P00533	EGFR	P12931	SRC	Y764	S768T	768	Missense	distal	4	no	23.344	23.338	EPSD;PhosphoSitePlus	COSMIC	20.673	Down-regulation
TK_Src_SrcA_SRC_Y	P00533	EGFR	P12931	SRC	Y764	D761Y	761	Missense	distal	-3	no	23.344	21.955	EPSD;PhosphoSitePlus	COSMIC	20.673	Down-regulation
TK_Src_SrcA_SRC_Y	P00533	EGFR	P12931	SRC	Y764	L760P	760	Missense	distal	-4	no	23.344	23.978	EPSD;PhosphoSitePlus	COSMIC	20.673	Up-regulation
TK_Src_SrcA_SRC_Y	P00533	EGFR	P12931	SRC	Y764	V765L	765	Missense	proximal	1	no	23.344	22.581	EPSD;PhosphoSitePlus	COSMIC	20.673	Down-regulation
TK_Src_SrcA_SRC_Y	P00533	EGFR	P12931	SRC	Y764	E758K	758	Missense	distal	-6	no	23.344	23.331	EPSD;PhosphoSitePlus	COSMIC	20.673	Down-regulation
TK_Src_SrcA_SRC_Y	P00533	EGFR	P12931	SRC	Y764	L760F	760	Missense	distal	-4	no	23.344	23.113	EPSD;PhosphoSitePlus	COSMIC	20.673	Down-regulation
TK_Src_SrcA_SRC_Y	P00533	EGFR	P12931	SRC	Y764	M766Q	766	Missense	proximal	2	no	23.344	23.269	EPSD;PhosphoSitePlus	COSMIC	20.673	Down-regulation
TK_Src_SrcA_SRC_Y	P00533	EGFR	P12931	SRC	Y764	K757R	757	Missense	distal	-7	no	23.344	23.677	EPSD;PhosphoSitePlus	COSMIC	20.673	Up-regulation
TK_Src_SrcA_SRC_Y	P00533	EGFR	P12931	SRC	Y764	V765G	765	Missense	proximal	1	no	23.344	24.242	EPSD;PhosphoSitePlus	COSMIC	20.673	Up-regulation
TK_Src_SrcA_SRC_Y	P00533	EGFR	P12931	SRC	Y764	E758D	758	Missense	distal	-6	no	23.344	23.421	EPSD;PhosphoSitePlus	COSMIC	20.673	Up-regulation
TK_Src_SrcA_SRC_Y	P00533	EGFR	P12931	SRC	Y764	V769A	769	Missense	distal	5	no	23.344	23.202	EPSD;PhosphoSitePlus	COSMIC	20.673	Down-regulation
TK_Src_SrcA_SRC_Y	P00533	EGFR	P12931	SRC	Y764	M766L	766	Missense	proximal	2	no	23.344	22.687	EPSD;PhosphoSitePlus	COSMIC	20.673	Down-regulation
TK_Src_SrcA_SRC_Y	P00533	EGFR	P12931	SRC	Y764	M766I	766	Missense	proximal	2	no	23.344	22.414	EPSD;PhosphoSitePlus	COSMIC	20.673	Down-regulation
TK_Src_SrcA_SRC_Y	P00533	EGFR	P12931	SRC	Y764	S768V	768	Missense	distal	4	no	23.344	23.315	EPSD;PhosphoSitePlus	COSMIC	20.673	Down-regulation
TK_Src_SrcA_SRC_Y	P00533	EGFR	P12931	SRC	Y764	K757M	757	Missense	distal	-7	no	23.344	22.888	EPSD;PhosphoSitePlus	COSMIC	20.673	Down-regulation
TK_Src_SrcA_SRC_Y	P00533	EGFR	P12931	SRC	Y764	M766T	766	Missense	proximal	2	no	23.344	23.492	EPSD;PhosphoSitePlus	COSMIC	20.673	Up-regulation
TK_Src_SrcA_SRC_Y	P00533	EGFR	P12931	SRC	Y869	H870R	870	Missense	proximal	1	no	21.933	22.007	EPSD;PhosphoSitePlus	COSMIC	20.673	Up-regulation
TK_Src_SrcA_SRC_Y	P00533	EGFR	P12931	SRC	Y869	A864T	864	Missense	distal	-5	no	21.933	21.723	EPSD;PhosphoSitePlus	COSMIC	20.673	Down-regulation
TK_Src_SrcA_SRC_Y	P00533	EGFR	P12931	SRC	Y869	G873E	873	Missense	distal	4	no	21.933	21.946	EPSD;PhosphoSitePlus	COSMIC	20.673	Up-regulation
TK_Src_SrcA_SRC_Y	P00533	EGFR	P12931	SRC	Y869	A871G	871	Missense	proximal	2	no	21.933	21.158	EPSD;PhosphoSitePlus	COSMIC	20.673	Down-regulation
TK_Src_SrcA_SRC_Y	P00533	EGFR	P12931	SRC	Y869	A871V	871	Missense	proximal	2	no	21.933	22.144	EPSD;PhosphoSitePlus	COSMIC	20.673	Up-regulation
TK_Src_SrcA_SRC_Y	P00533	EGFR	P12931	SRC	Y869	A864E	864	Missense	distal	-5	no	21.933	22.216	EPSD;PhosphoSitePlus	COSMIC	20.673	Up-regulation
TK_Src_SrcA_SRC_Y	P00533	EGFR	P12931	SRC	Y869	K867T	867	Missense	proximal	-2	no	21.933	21.865	EPSD;PhosphoSitePlus	COSMIC	20.673	Down-regulation
TK_Src_SrcA_SRC_Y	P00533	EGFR	P12931	SRC	Y869	A871E	871	Missense	proximal	2	no	21.933	22.113	EPSD;PhosphoSitePlus	COSMIC	20.673	Up-regulation
TK_Src_SrcA_SRC_Y	P00533	EGFR	P12931	SRC	Y869	E868K	868	Missense	proximal	-1	no	21.933	20.025	EPSD;PhosphoSitePlus	COSMIC	20.673	Loss
TK_Src_SrcA_SRC_Y	P00533	EGFR	P12931	SRC	Y869	G863D	863	Missense	distal	-6	no	21.933	22.240	EPSD;PhosphoSitePlus	COSMIC	20.673	Up-regulation
TK_Src_SrcA_SRC_Y	P00533	EGFR	P12931	SRC	Y869	E866D	866	Missense	distal	-3	no	21.933	21.979	EPSD;PhosphoSitePlus	COSMIC;GDSC;CCLE	20.673	Up-regulation
TK_Src_SrcA_SRC_Y	P00533	EGFR	P12931	SRC	Y869	L862Q	862	Missense	distal	-7	no	21.933	22.192	EPSD;PhosphoSitePlus	COSMIC	20.673	Up-regulation
TK_Src_SrcA_SRC_Y	P00533	EGFR	P12931	SRC	Y869	A871T	871	Missense	proximal	2	no	21.933	22.027	EPSD;PhosphoSitePlus	COSMIC	20.673	Up-regulation
TK_Src_SrcA_SRC_Y	P00533	EGFR	P12931	SRC	Y869	L862V	862	Missense	distal	-7	no	21.933	21.897	EPSD;PhosphoSitePlus	COSMIC	20.673	Down-regulation
TK_Src_SrcA_SRC_Y	P00533	EGFR	P12931	SRC	Y869	H870N	870	Missense	proximal	1	no	21.933	21.987	EPSD;PhosphoSitePlus	COSMIC	20.673	Up-regulation
TK_Src_SrcA_SRC_Y	P00533	EGFR	P12931	SRC	Y869	E868G	868	Missense	proximal	-1	no	21.933	20.466	EPSD;PhosphoSitePlus	COSMIC	20.673	Loss
TK_Src_SrcA_SRC_Y	P00533	EGFR	P12931	SRC	Y869	G873Q	873	Missense	distal	4	no	21.933	21.953	EPSD;PhosphoSitePlus	COSMIC	20.673	Up-regulation
TK_Src_SrcA_SRC_Y	P00533	EGFR	P12931	SRC	Y869	E872K	872	Missense	distal	3	no	21.933	20.596	EPSD;PhosphoSitePlus	COSMIC	20.673	Loss
TK_Src_SrcA_SRC_Y	P00533	EGFR	P12931	SRC	Y869	G863S	863	Missense	distal	-6	no	21.933	22.076	EPSD;PhosphoSitePlus	COSMIC	20.673	Up-regulation
TK_Src_SrcA_SRC_Y	P00533	EGFR	P12931	SRC	Y869	E868D	868	Missense	proximal	-1	no	21.933	21.024	EPSD;PhosphoSitePlus	COSMIC	20.673	Down-regulation
TK_Src_SrcA_SRC_Y	P00533	EGFR	P12931	SRC	Y869	G874D	874	Missense	distal	5	no	21.933	21.569	EPSD;PhosphoSitePlus	COSMIC	20.673	Down-regulation
TK_Src_SrcA_SRC_Y	P00533	EGFR	P12931	SRC	Y869	G874S	874	Missense	distal	5	no	21.933	21.727	EPSD;PhosphoSitePlus	COSMIC	20.673	Down-regulation
TK_Src_SrcA_SRC_Y	P00533	EGFR	P12931	SRC	Y869	H870Y	870	Missense	proximal	1	no	21.933	22.980	EPSD;PhosphoSitePlus	COSMIC	20.673	Up-regulation
TK_Src_SrcA_SRC_Y	P00533	EGFR	P12931	SRC	Y869	L862R	862	Missense	distal	-7	no	21.933	22.417	EPSD;PhosphoSitePlus	COSMIC	20.673	Up-regulation
TK_Src_SrcA_SRC_Y	P00533	EGFR	P12931	SRC	Y869	Y869C	869	Missense	central	0	yes	21.933	0.000	EPSD;PhosphoSitePlus	COSMIC	20.673	Loss
TK_Src_SrcA_SRC_Y	P00533	EGFR	P12931	SRC	Y869	L862P	862	Missense	distal	-7	no	21.933	22.048	EPSD;PhosphoSitePlus	COSMIC	20.673	Up-regulation
TK_Src_SrcA_SRC_Y	P00533	EGFR	P12931	SRC	Y869	E865K	865	Missense	distal	-4	no	21.933	20.763	EPSD;PhosphoSitePlus	COSMIC	20.673	Down-regulation
TK_Src_SrcA_SRC_Y	P00533	EGFR	P12931	SRC	Y869	E866V	866	Missense	distal	-3	no	21.933	20.054	EPSD;PhosphoSitePlus	COSMIC	20.673	Loss
TK_Src_SrcA_SRC_Y	P00533	EGFR	P12931	SRC	Y869	E866G	866	Missense	distal	-3	no	21.933	21.330	EPSD;PhosphoSitePlus	COSMIC	20.673	Down-regulation
TK_Src_SrcA_SRC_Y	P00533	EGFR	P12931	SRC	Y869	K875R	875	Missense	distal	6	no	21.933	21.901	EPSD;PhosphoSitePlus	COSMIC	20.673	Down-regulation
TK_Src_SrcA_SRC_Y	P00533	EGFR	P12931	SRC	Y869	G873R	873	Missense	distal	4	no	21.933	21.932	EPSD;PhosphoSitePlus	COSMIC	20.673	Down-regulation
TK_Src_SrcA_SRC_Y	P00533	EGFR	P12931	SRC	Y869	E868V	868	Missense	proximal	-1	no	21.933	22.457	EPSD;PhosphoSitePlus	COSMIC	20.673	Up-regulation
TK_Src_SrcA_SRC_Y	P00533	EGFR	P12931	SRC	Y869	E866Q	866	Missense	distal	-3	no	21.933	21.053	EPSD;PhosphoSitePlus	COSMIC	20.673	Down-regulation
TK_Src_SrcA_SRC_Y	P00533	EGFR	P12931	SRC	Y869	G863V	863	Missense	distal	-6	no	21.933	21.826	EPSD;PhosphoSitePlus	COSMIC	20.673	Down-regulation
TK_Src_SrcA_SRC_Y	P00533	EGFR	P12931	SRC	Y998	F997L	997	Missense	proximal	-1	no	22.476	23.335	EPSD	COSMIC	20.673	Up-regulation
TK_Src_SrcA_SRC_Y	P00533	EGFR	P12931	SRC	Y998	M1002V	1002	Missense	distal	4	no	22.476	22.512	EPSD	COSMIC	20.673	Up-regulation
TK_Src_SrcA_SRC_Y	P00533	EGFR	P12931	SRC	Y998	E1004K	1004	Missense	distal	6	no	22.476	22.474	EPSD	COSMIC	20.673	Down-regulation
TK_Src_SrcA_SRC_Y	P00533	EGFR	P12931	SRC	Y998	M1002I	1002	Missense	distal	4	no	22.476	22.523	EPSD	COSMIC	20.673	Up-regulation
TK_Src_SrcA_SRC_Y	P00533	EGFR	P12931	SRC	Y998	R999C	999	Missense	proximal	1	no	22.476	21.172	EPSD	COSMIC	20.673	Down-regulation
TK_Src_SrcA_SRC_Y	P00533	EGFR	P12931	SRC	Y1016	P1019S	1019	Missense	distal	3	no	20.800	20.061	PhosphoSitePlus;EPSD	COSMIC	20.673	Loss
TK_Src_SrcA_SRC_Y	P00533	EGFR	P12931	SRC	Y1016	D1014G	1014	Missense	proximal	-2	no	20.800	20.510	PhosphoSitePlus;EPSD	COSMIC	20.673	Loss
TK_Src_SrcA_SRC_Y	P00533	EGFR	P12931	SRC	Y1016	G1022S	1022	Missense	distal	6	no	20.800	20.780	PhosphoSitePlus;EPSD	COSMIC	20.673	Down-regulation
TK_Src_SrcA_SRC_Y	P00533	EGFR	P12931	SRC	Y1016	D1014V	1014	Missense	proximal	-2	no	20.800	19.233	PhosphoSitePlus;EPSD	COSMIC	20.673	Loss
TK_Src_SrcA_SRC_Y	P00533	EGFR	P12931	SRC	Y1016	V1011E	1011	Missense	distal	-5	no	20.800	21.082	PhosphoSitePlus;EPSD	COSMIC	20.673	Up-regulation
TK_Src_SrcA_SRC_Y	P00533	EGFR	P12931	SRC	Y1016	D1014N	1014	Missense	proximal	-2	no	20.800	20.520	PhosphoSitePlus;EPSD	COSMIC	20.673	Loss
TK_Src_SrcA_SRC_Y	P00533	EGFR	P12931	SRC	Y1016	V1010L	1010	Missense	distal	-6	no	20.800	20.981	PhosphoSitePlus;EPSD	COSMIC	20.673	Up-regulation
TK_Src_SrcA_SRC_Y	P00533	EGFR	P12931	SRC	Y1016	V1011M	1011	Missense	distal	-5	no	20.800	20.481	PhosphoSitePlus;EPSD	COSMIC;GDSC;CCLE	20.673	Loss
TK_Src_SrcA_SRC_Y	P00533	EGFR	P12931	SRC	Y1016	D1012H	1012	Missense	distal	-4	no	20.800	19.639	PhosphoSitePlus;EPSD	COSMIC	20.673	Loss
TK_Src_SrcA_SRC_Y	P00533	EGFR	P12931	SRC	Y1016	E1015K	1015	Missense	proximal	-1	no	20.800	18.891	PhosphoSitePlus;EPSD	COSMIC	20.673	Loss
TK_Src_SrcA_SRC_Y	P00533	EGFR	P12931	SRC	Y1016	D1009Y	1009	Missense	distal	-7	no	20.800	20.349	PhosphoSitePlus;EPSD	COSMIC	20.673	Loss
TK_Src_SrcA_SRC_Y	P00533	EGFR	P12931	SRC	Y1016	Q1020H	1020	Missense	distal	4	no	20.800	20.791	PhosphoSitePlus;EPSD	COSMIC	20.673	Down-regulation
TK_Src_SrcA_SRC_Y	P00533	EGFR	P12931	SRC	Y1016	V1010M	1010	Missense	distal	-6	no	20.800	20.509	PhosphoSitePlus;EPSD	COSMIC	20.673	Loss
TK_Src_SrcA_SRC_Y	P00533	EGFR	P12931	SRC	Y1125	A1118T	1118	Missense	distal	-7	no	24.203	24.623	EPSD;PhosphoSitePlus	COSMIC;GDSC;CCLE	20.673	Up-regulation
TK_Src_SrcA_SRC_Y	P00533	EGFR	P12931	SRC	Y1125	H1124Q	1124	Missense	proximal	-1	no	24.203	24.140	EPSD;PhosphoSitePlus	COSMIC;CCLE	20.673	Down-regulation
TK_Src_SrcA_SRC_Y	P00533	EGFR	P12931	SRC	Y1125	S1130G	1130	Missense	distal	5	no	24.203	24.409	EPSD;PhosphoSitePlus	COSMIC;GDSC;CCLE	20.673	Up-regulation
TK_Src_SrcA_SRC_Y	P00533	EGFR	P12931	SRC	Y1125	H1129Y	1129	Missense	distal	4	no	24.203	24.182	EPSD;PhosphoSitePlus	COSMIC	20.673	Down-regulation
TK_Src_SrcA_SRC_Y	P00533	EGFR	P12931	SRC	Y1125	S1130R	1130	Missense	distal	5	no	24.203	24.228	EPSD;PhosphoSitePlus	COSMIC	20.673	Up-regulation
TK_Src_SrcA_SRC_Y	P00533	EGFR	P12931	SRC	Y1125	A1118S	1118	Missense	distal	-7	no	24.203	24.527	EPSD;PhosphoSitePlus	COSMIC	20.673	Up-regulation
TK_Src_SrcA_SRC_Y	P00533	EGFR	P12931	SRC	Y1125	S1120N	1120	Missense	distal	-5	no	24.203	24.075	EPSD;PhosphoSitePlus	COSMIC	20.673	Down-regulation
TK_Src_SrcA_SRC_Y	P00533	EGFR	P12931	SRC	Y1125	D1127N	1127	Missense	proximal	2	no	24.203	24.417	EPSD;PhosphoSitePlus	COSMIC;GDSC;CCLE	20.673	Up-regulation
TK_Src_SrcA_SRC_Y	P00533	EGFR	P12931	SRC	Y1172	P1170S	1170	Missense	proximal	-2	no	22.551	21.765	EPSD	COSMIC	20.673	Down-regulation
TK_Src_SrcA_SRC_Y	P00533	EGFR	P12931	SRC	Y1172	Q1174R	1174	Missense	proximal	2	no	22.551	22.202	EPSD	COSMIC;CCLE	20.673	Down-regulation
TK_Src_SrcA_SRC_Y	P00533	EGFR	P12931	SRC	Y1172	L1167V	1167	Missense	distal	-5	no	22.551	22.712	EPSD	COSMIC	20.673	Up-regulation
TK_Src_SrcA_SRC_Y	P00533	EGFR	P12931	SRC	Y1172	D1175V	1175	Missense	distal	3	no	22.551	23.301	EPSD	COSMIC	20.673	Up-regulation
TK_Src_SrcA_SRC_Y	P00533	EGFR	P12931	SRC	Y1172	D1168Y	1168	Missense	distal	-4	no	22.551	21.558	EPSD	COSMIC	20.673	Down-regulation
TK_Src_SrcA_SRC_Y	P16662	UGT2B7	P12931	SRC	Y438	N434I	434	Missense	distal	-4	no	22.427	20.887	PhosphoSitePlus	COSMIC	20.673	Down-regulation
TK_Src_SrcA_SRC_Y	P16662	UGT2B7	P12931	SRC	Y438	N441I	441	Missense	distal	3	no	22.427	22.041	PhosphoSitePlus	COSMIC	20.673	Down-regulation
TK_Src_SrcA_SRC_Y	O75955	FLOT1	P12931	SRC	Y56	K54N	54	Missense	proximal	-2	no	21.289	22.081	EPSD;PhosphoSitePlus	COSMIC	20.673	Up-regulation
TK_Src_SrcA_SRC_Y	O75955	FLOT1	P12931	SRC	Y56	I63L	63	Missense	distal	7	no	21.289	21.262	EPSD;PhosphoSitePlus	COSMIC	20.673	Down-regulation
TK_Src_SrcA_SRC_Y	P11413	G6PD	P12931	SRC	Y107	R104H	104	Missense	distal	-3	no	20.867	20.832	EPSD	COSMIC	20.673	Down-regulation
TK_Src_SrcA_SRC_Y	P11413	G6PD	P12931	SRC	Y107	Y112H	112	Missense	distal	5	no	20.867	20.583	EPSD	COSMIC	20.673	Loss
TK_Src_SrcA_SRC_Y	P11413	G6PD	P12931	SRC	Y112	Y112H	112	Missense	central	0	yes	20.713	0.000	EPSD	COSMIC	20.673	Loss
TK_Src_SrcA_SRC_Y	P11413	G6PD	P12931	SRC	Y118	Y112H	112	Missense	distal	-6	no	21.248	21.078	EPSD	COSMIC	20.673	Down-regulation
TK_Src_SrcA_SRC_Y	P11413	G6PD	P12931	SRC	Y139	F138V	138	Missense	proximal	-1	no	19.299	21.268	EPSD	COSMIC	20.673	Gain
TK_Src_SrcA_SRC_Y	P11413	G6PD	P12931	SRC	Y147	E148K	148	Missense	proximal	1	no	22.865	20.471	EPSD	COSMIC	20.673	Loss
TK_Src_SrcA_SRC_Y	P11413	G6PD	P12931	SRC	Y507	T506I	506	Missense	proximal	-1	no	19.836	20.815	PhosphoSitePlus;EPSD	COSMIC	20.673	Gain
TK_Src_SrcA_SRC_Y	Q15691	MAPRE1	P12931	SRC	Y124	D123Y	123	Missense	proximal	-1	no	20.498	21.660	EPSD	COSMIC	20.673	Gain
TK_Src_SrcA_SRC_Y	P12931	SRC	P12931	SRC	Y338	M344I	344	Missense	distal	6	no	23.077	23.055	EPSD;PhosphoSitePlus	COSMIC	20.673	Down-regulation
TK_Src_SrcA_SRC_Y	P12931	SRC	P12931	SRC	Y338	T341A	341	Missense	distal	3	no	23.077	23.033	EPSD;PhosphoSitePlus	COSMIC	20.673	Down-regulation
TK_Src_SrcA_SRC_Y	P12931	SRC	P12931	SRC	Y338	S345C	345	Missense	distal	7	no	23.077	23.187	EPSD;PhosphoSitePlus	COSMIC	20.673	Up-regulation
TK_Src_SrcA_SRC_Y	P12931	SRC	P12931	SRC	Y338	T341M	341	Missense	distal	3	no	23.077	23.236	EPSD;PhosphoSitePlus	COSMIC	20.673	Up-regulation
TK_Src_SrcA_SRC_Y	P12931	SRC	P12931	SRC	Y338	T341R	341	Missense	distal	3	no	23.077	21.941	EPSD;PhosphoSitePlus	COSMIC	20.673	Down-regulation
TK_Src_SrcA_SRC_Y	P12931	SRC	P12931	SRC	Y419	A421V	421	Missense	proximal	2	no	24.549	24.760	EPSD;PhosphoSitePlus	COSMIC	20.673	Up-regulation
TK_Src_SrcA_SRC_Y	P12931	SRC	P12931	SRC	Y419	Y419H	419	Missense	central	0	yes	24.549	0.000	EPSD;PhosphoSitePlus	COSMIC	20.673	Loss
TK_Src_SrcA_SRC_Y	P12931	SRC	P12931	SRC	Y439	E435K	435	Missense	distal	-4	no	21.282	20.112	EPSD	COSMIC	20.673	Loss
TK_Src_SrcA_SRC_Y	P12931	SRC	P12931	SRC	Y439	Y439S	439	Missense	central	0	yes	21.282	0.000	EPSD	COSMIC	20.673	Loss
TK_Src_SrcA_SRC_Y	P12931	SRC	P12931	SRC	Y439	A433T	433	Missense	distal	-6	no	21.282	21.319	EPSD	COSMIC	20.673	Up-regulation
TK_Src_SrcA_SRC_Y	P12931	SRC	P12931	SRC	Y439	L438R	438	Missense	proximal	-1	no	21.282	19.630	EPSD	COSMIC	20.673	Loss
TK_Src_SrcA_SRC_Y	P12931	SRC	P12931	SRC	Y439	P434T	434	Missense	distal	-5	no	21.282	21.075	EPSD	COSMIC	20.673	Down-regulation
TK_Src_SrcA_SRC_Y	P12931	SRC	P12931	SRC	Y439	P434S	434	Missense	distal	-5	no	21.282	21.384	EPSD	COSMIC	20.673	Up-regulation
TK_Src_SrcA_SRC_Y	P33151	CDH5	P12931	SRC	Y658	L663F	663	Missense	distal	5	no	20.985	21.042	EPSD;PhosphoSitePlus	COSMIC	20.673	Up-regulation
TK_Src_SrcA_SRC_Y	P33151	CDH5	P12931	SRC	Y658	G651S	651	Missense	distal	-7	no	20.985	21.358	EPSD;PhosphoSitePlus	COSMIC	20.673	Up-regulation
TK_Src_SrcA_SRC_Y	P33151	CDH5	P12931	SRC	Y658	S661L	661	Missense	distal	3	no	20.985	21.626	EPSD;PhosphoSitePlus	COSMIC	20.673	Up-regulation
TK_Src_SrcA_SRC_Y	P33151	CDH5	P12931	SRC	Y658	S665L	665	Missense	distal	7	no	20.985	20.998	EPSD;PhosphoSitePlus	COSMIC	20.673	Up-regulation
TK_Src_SrcA_SRC_Y	P33151	CDH5	P12931	SRC	Y685	P692S	692	Missense	distal	7	no	21.644	21.624	EPSD;PhosphoSitePlus	COSMIC	20.673	Down-regulation
TK_Src_SrcA_SRC_Y	P33151	CDH5	P12931	SRC	Y685	K690E	690	Missense	distal	5	no	21.644	21.611	EPSD;PhosphoSitePlus	COSMIC	20.673	Down-regulation
TK_Src_SrcA_SRC_Y	P33151	CDH5	P12931	SRC	Y685	A680T	680	Missense	distal	-5	no	21.644	21.433	EPSD;PhosphoSitePlus	COSMIC	20.673	Down-regulation
TK_Src_SrcA_SRC_Y	P33151	CDH5	P12931	SRC	Y725	D719E	719	Missense	distal	-6	no	24.899	24.821	EPSD	COSMIC	20.673	Down-regulation
TK_Src_SrcA_SRC_Y	P33151	CDH5	P12931	SRC	Y725	G722S	722	Missense	distal	-3	no	24.899	25.080	EPSD	COSMIC	20.673	Up-regulation
TK_Src_SrcA_SRC_Y	Q92556	ELMO1	P12931	SRC	Y395	Y395F	395	Missense	central	0	yes	20.907	0.000	EPSD	COSMIC	20.673	Loss
TK_Src_SrcA_SRC_Y	Q92556	ELMO1	P12931	SRC	Y395	Y395N	395	Missense	central	0	yes	20.907	0.000	EPSD	COSMIC	20.673	Loss
TK_Src_SrcA_SRC_Y	Q92556	ELMO1	P12931	SRC	Y588	G589R	589	Missense	proximal	1	no	21.554	20.561	EPSD	COSMIC	20.673	Loss
TK_Src_SrcA_SRC_Y	Q92556	ELMO1	P12931	SRC	Y588	G589E	589	Missense	proximal	1	no	21.554	22.538	EPSD	COSMIC	20.673	Up-regulation
TK_Src_SrcA_SRC_Y	Q92556	ELMO1	P12931	SRC	Y588	H583Y	583	Missense	distal	-5	no	21.554	20.889	EPSD	COSMIC	20.673	Down-regulation
TK_Src_SrcA_SRC_Y	Q92556	ELMO1	P12931	SRC	Y724	P717T	717	Missense	distal	-7	no	20.794	21.011	EPSD;PhosphoSitePlus	COSMIC	20.673	Up-regulation
TK_Src_SrcA_SRC_Y	P32004	L1CAM	P12931	SRC	Y420	Y418N	418	Missense	proximal	-2	no	19.825	20.995	EPSD	COSMIC	20.673	Gain
TK_Src_SrcA_SRC_Y	P32004	L1CAM	P12931	SRC	Y589	T595I	595	Missense	distal	6	no	21.043	21.073	EPSD	COSMIC	20.673	Up-regulation
TK_Src_SrcA_SRC_Y	P46934	NEDD4	P12931	SRC	Y412	L406P	406	Missense	distal	-6	no	20.940	20.960	EPSD	COSMIC	20.673	Up-regulation
TK_Src_SrcA_SRC_Y	P46934	NEDD4	P12931	SRC	Y976	R977Q	977	Missense	proximal	1	no	20.367	21.360	EPSD	COSMIC	20.673	Gain
TK_Src_SrcA_SRC_Y	P46934	NEDD4	P12931	SRC	Y1004	D1003N	1003	Missense	proximal	-1	no	21.103	20.154	EPSD	COSMIC	20.673	Loss
TK_Src_SrcA_SRC_Y	P46934	NEDD4	P12931	SRC	Y1004	K1000R	1000	Missense	distal	-4	no	21.103	21.822	EPSD	COSMIC	20.673	Up-regulation
TK_Src_SrcA_SRC_Y	P29350	PTPN6	P12931	SRC	Y61	F60L	60	Missense	proximal	-1	no	20.996	21.855	EPSD	COSMIC	20.673	Up-regulation
TK_Src_SrcA_SRC_Y	P29350	PTPN6	P12931	SRC	Y214	T216A	216	Missense	proximal	2	no	21.100	21.007	EPSD	COSMIC	20.673	Down-regulation
TK_Src_SrcA_SRC_Y	P29350	PTPN6	P12931	SRC	Y214	R210Q	210	Missense	distal	-4	no	21.100	20.721	EPSD	COSMIC	20.673	Down-regulation
TK_Src_SrcA_SRC_Y	P29350	PTPN6	P12931	SRC	Y214	P212S	212	Missense	proximal	-2	no	21.100	20.314	EPSD	COSMIC	20.673	Loss
TK_Src_SrcA_SRC_Y	P29350	PTPN6	P12931	SRC	Y301	I302N	302	Missense	proximal	1	no	20.265	20.809	EPSD	COSMIC	20.673	Gain
TK_Src_SrcA_SRC_Y	P29350	PTPN6	P12931	SRC	Y536	E535G	535	Missense	proximal	-1	no	23.003	21.536	EPSD;PhosphoSitePlus	COSMIC	20.673	Down-regulation
TK_Src_SrcA_SRC_Y	P29350	PTPN6	P12931	SRC	Y536	G537R	537	Missense	proximal	1	no	23.003	22.009	EPSD;PhosphoSitePlus	COSMIC	20.673	Down-regulation
TK_Src_SrcA_SRC_Y	P29350	PTPN6	P12931	SRC	Y564	N571Y	571	Missense	distal	7	no	25.378	25.398	PhosphoSitePlus;EPSD	COSMIC	20.673	Up-regulation
TK_Src_SrcA_SRC_Y	P51812	RPS6KA3	P12931	SRC	Y483	D481G	481	Missense	proximal	-2	no	23.207	22.917	EPSD;PhosphoSitePlus	COSMIC	20.673	Down-regulation
TK_Src_SrcA_SRC_Y	P51812	RPS6KA3	P12931	SRC	Y483	Y483C	483	Missense	central	0	yes	23.207	0.000	EPSD;PhosphoSitePlus	COSMIC	20.673	Loss
TK_Src_SrcA_SRC_Y	P51812	RPS6KA3	P12931	SRC	Y580	M576R	576	Missense	distal	-4	no	20.136	21.360	EPSD;PhosphoSitePlus	COSMIC;CCLE	20.673	Gain
TK_Src_SrcA_SRC_Y	Q05397	PTK2	P12931	SRC	Y397	S390A	390	Missense	distal	-7	no	21.314	20.990	EPSD;PhosphoSitePlus	COSMIC	20.673	Down-regulation
TK_Src_SrcA_SRC_Y	Q05397	PTK2	P12931	SRC	Y397	D402V	402	Missense	distal	5	no	21.314	21.570	EPSD;PhosphoSitePlus	COSMIC	20.673	Up-regulation
TK_Src_SrcA_SRC_Y	Q05397	PTK2	P12931	SRC	Y397	E404A	404	Missense	distal	7	no	21.314	21.296	EPSD;PhosphoSitePlus	COSMIC	20.673	Down-regulation
TK_Src_SrcA_SRC_Y	Q05397	PTK2	P12931	SRC	Y397	V391A	391	Missense	distal	-6	no	21.314	21.475	EPSD;PhosphoSitePlus	COSMIC	20.673	Up-regulation
TK_Src_SrcA_SRC_Y	Q05397	PTK2	P12931	SRC	Y407	D402V	402	Missense	distal	-5	no	23.970	23.789	EPSD;PhosphoSitePlus	COSMIC	20.673	Down-regulation
TK_Src_SrcA_SRC_Y	Q05397	PTK2	P12931	SRC	Y407	D405G	405	Missense	proximal	-2	no	23.970	23.680	EPSD;PhosphoSitePlus	COSMIC	20.673	Down-regulation
TK_Src_SrcA_SRC_Y	Q05397	PTK2	P12931	SRC	Y407	R413S	413	Missense	distal	6	no	23.970	23.975	EPSD;PhosphoSitePlus	COSMIC	20.673	Up-regulation
TK_Src_SrcA_SRC_Y	Q05397	PTK2	P12931	SRC	Y407	E404A	404	Missense	distal	-3	no	23.970	22.642	EPSD;PhosphoSitePlus	COSMIC	20.673	Down-regulation
TK_Src_SrcA_SRC_Y	Q05397	PTK2	P12931	SRC	Y441	P447S	447	Missense	distal	6	no	21.321	21.305	EPSD;PhosphoSitePlus	COSMIC	20.673	Down-regulation
TK_Src_SrcA_SRC_Y	Q05397	PTK2	P12931	SRC	Y441	S443R	443	Missense	proximal	2	no	21.321	20.489	EPSD;PhosphoSitePlus	COSMIC	20.673	Loss
TK_Src_SrcA_SRC_Y	Q05397	PTK2	P12931	SRC	Y441	Y441F	441	Missense	central	0	yes	21.321	0.000	EPSD;PhosphoSitePlus	COSMIC	20.673	Loss
TK_Src_SrcA_SRC_Y	Q05397	PTK2	P12931	SRC	Y576	R569L	569	Missense	distal	-7	no	24.854	24.370	EPSD;PhosphoSitePlus	COSMIC	20.673	Down-regulation
TK_Src_SrcA_SRC_Y	Q05397	PTK2	P12931	SRC	Y576	A579V	579	Missense	distal	3	no	24.854	25.424	EPSD;PhosphoSitePlus	COSMIC	20.673	Up-regulation
TK_Src_SrcA_SRC_Y	Q05397	PTK2	P12931	SRC	Y577	A579V	579	Missense	proximal	2	no	22.027	22.238	EPSD;PhosphoSitePlus	COSMIC	20.673	Up-regulation
TK_Src_SrcA_SRC_Y	Q05397	PTK2	P12931	SRC	Y861	D868N	868	Missense	distal	7	no	23.332	23.330	EPSD;PhosphoSitePlus	COSMIC	20.673	Down-regulation
TK_Src_SrcA_SRC_Y	Q05397	PTK2	P12931	SRC	Y925	G930C	930	Missense	distal	5	no	26.130	26.382	PhosphoSitePlus;EPSD	COSMIC	20.673	Up-regulation
TK_Src_SrcA_SRC_Y	Q05397	PTK2	P12931	SRC	Y925	D918G	918	Missense	distal	-7	no	26.130	25.707	PhosphoSitePlus;EPSD	COSMIC	20.673	Down-regulation
TK_Src_SrcA_SRC_Y	Q05397	PTK2	P12931	SRC	Y925	E926K	926	Missense	proximal	1	no	26.130	23.735	PhosphoSitePlus;EPSD	COSMIC	20.673	Down-regulation
TK_Src_SrcA_SRC_Y	Q05397	PTK2	P12931	SRC	Y925	Y925C	925	Missense	central	0	yes	26.130	0.000	PhosphoSitePlus;EPSD	COSMIC	20.673	Loss
TK_Src_SrcA_SRC_Y	Q05397	PTK2	P12931	SRC	Y925	R919L	919	Missense	distal	-6	no	26.130	26.201	PhosphoSitePlus;EPSD	COSMIC	20.673	Up-regulation
TK_Src_SrcA_SRC_Y	Q05397	PTK2	P12931	SRC	Y925	R919Q	919	Missense	distal	-6	no	26.130	26.232	PhosphoSitePlus;EPSD	COSMIC	20.673	Up-regulation
TK_Src_SrcA_SRC_Y	P30304	CDC25A	P12931	SRC	Y486	P484S	484	Missense	proximal	-2	no	21.860	21.074	EPSD;PhosphoSitePlus	COSMIC	20.673	Down-regulation
TK_Src_SrcA_SRC_Y	P30304	CDC25A	P12931	SRC	Y486	Y486D	486	Missense	central	0	yes	21.860	0.000	EPSD;PhosphoSitePlus	COSMIC	20.673	Loss
TK_Src_SrcA_SRC_Y	P07355	ANXA2	P12931	SRC	Y24	K28Q	28	Missense	distal	4	no	22.045	22.052	PhosphoSitePlus	COSMIC;CCLE	20.673	Up-regulation
TK_Src_SrcA_SRC_Y	P07355	ANXA2	P12931	SRC	Y30	R37W	37	Missense	distal	7	no	20.619	20.715	EPSD	COSMIC	20.673	Gain
TK_Src_SrcA_SRC_Y	P07355	ANXA2	P12931	SRC	Y30	K28Q	28	Missense	proximal	-2	no	20.619	20.788	EPSD	COSMIC;CCLE	20.673	Gain
TK_Src_SrcA_SRC_Y	P07355	ANXA2	P12931	SRC	Y30	A35T	35	Missense	distal	5	no	20.619	20.833	EPSD	COSMIC	20.673	Gain
TK_Src_SrcA_SRC_Y	P07355	ANXA2	P12931	SRC	Y188	I191F	191	Missense	distal	3	no	21.347	21.674	EPSD	COSMIC	20.673	Up-regulation
TK_Src_SrcA_SRC_Y	P07355	ANXA2	P12931	SRC	Y275	R273L	273	Missense	proximal	-2	no	21.450	21.451	EPSD	COSMIC	20.673	Up-regulation
TK_Src_SrcA_SRC_Y	P35228	NOS2	P12931	SRC	Y46	T40I	40	Missense	distal	-6	no	20.974	21.003	EPSD	COSMIC	20.673	Up-regulation
TK_Src_SrcA_SRC_Y	P35228	NOS2	P12931	SRC	Y46	S50N	50	Missense	distal	4	no	20.974	21.005	EPSD	COSMIC;GDSC;CCLE	20.673	Up-regulation
TK_Src_SrcA_SRC_Y	P35228	NOS2	P12931	SRC	Y46	V39E	39	Missense	distal	-7	no	20.974	21.323	EPSD	COSMIC	20.673	Up-regulation
TK_Src_SrcA_SRC_Y	P35228	NOS2	P12931	SRC	Y151	Y150H	150	Missense	proximal	-1	no	22.633	22.038	EPSD;PhosphoSitePlus	COSMIC	20.673	Down-regulation
TK_Src_SrcA_SRC_Y	P35228	NOS2	P12931	SRC	Y151	G152S	152	Missense	proximal	1	no	22.633	22.519	EPSD;PhosphoSitePlus	COSMIC	20.673	Down-regulation
TK_Src_SrcA_SRC_Y	O00560	SDCBP	P12931	SRC	Y46	L45I	45	Missense	proximal	-1	no	20.265	21.000	EPSD;PhosphoSitePlus	COSMIC	20.673	Gain
TK_Src_SrcA_SRC_Y	Q92734	TFG	P12931	SRC	Y33	H27R	27	Missense	distal	-6	no	23.856	23.888	PhosphoSitePlus;EPSD	COSMIC	20.673	Up-regulation
TK_Src_SrcA_SRC_Y	Q92734	TFG	P12931	SRC	Y33	M40L	40	Missense	distal	7	no	23.856	23.803	PhosphoSitePlus;EPSD	COSMIC	20.673	Down-regulation
TK_Src_SrcA_SRC_Y	O43490	PROM1	P12931	SRC	Y828	D830H	830	Missense	proximal	2	no	22.681	22.158	EPSD;PhosphoSitePlus	COSMIC	20.673	Down-regulation
TK_Src_SrcA_SRC_Y	Q9BZL6	PRKD2	P12931	SRC	Y717	P720H	720	Missense	distal	3	no	21.371	20.774	EPSD	COSMIC	20.673	Down-regulation
TK_Src_SrcA_SRC_Y	Q9BZL6	PRKD2	P12931	SRC	Y717	G713R	713	Missense	distal	-4	no	21.371	21.353	EPSD	COSMIC	20.673	Down-regulation
TK_Src_SrcA_SRC_Y	Q9BZL6	PRKD2	P12931	SRC	Y717	G713E	713	Missense	distal	-4	no	21.371	21.804	EPSD	COSMIC	20.673	Up-regulation
TK_Src_SrcA_SRC_Y	Q8IZL8	PELP1	P12931	SRC	Y920	E914D	914	Missense	distal	-6	no	23.884	23.961	PhosphoSitePlus	COSMIC	20.673	Up-regulation
TK_Src_SrcA_SRC_Y	Q9BXP5	SRRT	P12931	SRC	Y8	D9H	9	Missense	proximal	1	no	21.784	20.339	EPSD	COSMIC	20.673	Loss
TK_Src_SrcA_SRC_Y	Q9BXP5	SRRT	P12931	SRC	Y55	R60Q	60	Missense	distal	5	no	22.374	22.399	EPSD	COSMIC	20.673	Up-regulation
TK_Src_SrcA_SRC_Y	Q9BXP5	SRRT	P12931	SRC	Y55	R62L	62	Missense	distal	7	no	22.374	22.349	EPSD	COSMIC	20.673	Down-regulation
TK_Src_SrcA_SRC_Y	Q9BXP5	SRRT	P12931	SRC	Y58	R60Q	60	Missense	proximal	2	no	21.327	21.677	EPSD	COSMIC	20.673	Up-regulation
TK_Src_SrcA_SRC_Y	Q9BXP5	SRRT	P12931	SRC	Y58	R62L	62	Missense	distal	4	no	21.327	21.361	EPSD	COSMIC	20.673	Up-regulation
TK_Src_SrcA_SRC_Y	Q9BXP5	SRRT	P12931	SRC	Y92	S88N	88	Missense	distal	-4	no	21.544	21.958	PhosphoSitePlus;EPSD	COSMIC	20.673	Up-regulation
TK_Src_SrcA_SRC_Y	Q9BXP5	SRRT	P12931	SRC	Y836	Q842H	842	Missense	distal	6	no	21.974	21.986	EPSD;PhosphoSitePlus	COSMIC	20.673	Up-regulation
TK_Src_SrcA_SRC_Y	Q9BXP5	SRRT	P12931	SRC	Y836	Y836C	836	Missense	central	0	yes	21.974	0.000	EPSD;PhosphoSitePlus	COSMIC	20.673	Loss
TK_Src_SrcA_SRC_Y	Q9BXP5	SRRT	P12931	SRC	Y836	A838D	838	Missense	proximal	2	no	21.974	21.866	EPSD;PhosphoSitePlus	COSMIC	20.673	Down-regulation
TK_Src_SrcA_SRC_Y	Q9BXP5	SRRT	P12931	SRC	Y836	G834W	834	Missense	proximal	-2	no	21.974	19.667	EPSD;PhosphoSitePlus	COSMIC	20.673	Loss
TK_Src_SrcA_SRC_Y	Q96TC7	RMDN3	P12931	SRC	Y53	S57L	57	Missense	distal	4	no	21.617	21.624	EPSD	COSMIC	20.673	Up-regulation
TK_Src_SrcA_SRC_Y	Q96TC7	RMDN3	P12931	SRC	Y176	G174R	174	Missense	proximal	-2	no	21.241	19.883	PhosphoSitePlus	COSMIC	20.673	Loss
TK_Src_SrcA_SRC_Y	P04626	ERBB2	P12931	SRC	Y772	S779P	779	Missense	distal	7	no	22.817	22.836	EPSD	COSMIC	20.673	Up-regulation
TK_Src_SrcA_SRC_Y	P04626	ERBB2	P12931	SRC	Y772	V773M	773	Missense	proximal	1	no	22.817	22.194	EPSD	COSMIC	20.673	Down-regulation
TK_Src_SrcA_SRC_Y	P04626	ERBB2	P12931	SRC	Y772	V777E	777	Missense	distal	5	no	22.817	22.769	EPSD	COSMIC	20.673	Down-regulation
TK_Src_SrcA_SRC_Y	P04626	ERBB2	P12931	SRC	Y772	G778D	778	Missense	distal	6	no	22.817	22.776	EPSD	COSMIC	20.673	Down-regulation
TK_Src_SrcA_SRC_Y	P04626	ERBB2	P12931	SRC	Y772	V773A	773	Missense	proximal	1	no	22.817	23.401	EPSD	COSMIC	20.673	Up-regulation
TK_Src_SrcA_SRC_Y	P04626	ERBB2	P12931	SRC	Y772	A775G	775	Missense	distal	3	no	22.817	23.010	EPSD	COSMIC	20.673	Up-regulation
TK_Src_SrcA_SRC_Y	P04626	ERBB2	P12931	SRC	Y772	G776L	776	Missense	distal	4	no	22.817	22.849	EPSD	COSMIC	20.673	Up-regulation
TK_Src_SrcA_SRC_Y	P04626	ERBB2	P12931	SRC	Y877	D873G	873	Missense	distal	-4	no	22.382	21.723	PhosphoSitePlus	COSMIC	20.673	Down-regulation
TK_Src_SrcA_SRC_Y	P04626	ERBB2	P12931	SRC	Y877	E874D	874	Missense	distal	-3	no	22.382	22.427	PhosphoSitePlus	COSMIC	20.673	Up-regulation
TK_Src_SrcA_SRC_Y	P04626	ERBB2	P12931	SRC	Y877	T875I	875	Missense	proximal	-2	no	22.382	21.638	PhosphoSitePlus	COSMIC	20.673	Down-regulation
TK_Src_SrcA_SRC_Y	P04626	ERBB2	P12931	SRC	Y877	H878Y	878	Missense	proximal	1	no	22.382	23.428	PhosphoSitePlus	COSMIC	20.673	Up-regulation
TK_Src_SrcA_SRC_Y	P04626	ERBB2	P12931	SRC	Y877	D880H	880	Missense	distal	3	no	22.382	22.660	PhosphoSitePlus	COSMIC	20.673	Up-regulation
TK_Src_SrcA_SRC_Y	P04626	ERBB2	P12931	SRC	Y877	G882D	882	Missense	distal	5	no	22.382	22.017	PhosphoSitePlus	COSMIC	20.673	Down-regulation
TK_Src_SrcA_SRC_Y	P04626	ERBB2	P12931	SRC	Y877	E874K	874	Missense	distal	-3	no	22.382	20.671	PhosphoSitePlus	COSMIC	20.673	Loss
TK_Src_SrcA_SRC_Y	P04626	ERBB2	P12931	SRC	Y877	V884M	884	Missense	distal	7	no	22.382	22.383	PhosphoSitePlus	COSMIC	20.673	Up-regulation
TK_Src_SrcA_SRC_Y	P04626	ERBB2	P12931	SRC	Y877	H878R	878	Missense	proximal	1	no	22.382	22.456	PhosphoSitePlus	COSMIC	20.673	Up-regulation
TK_Src_SrcA_SRC_Y	P04626	ERBB2	P12931	SRC	Y877	D880N	880	Missense	distal	3	no	22.382	23.458	PhosphoSitePlus	COSMIC	20.673	Up-regulation
TK_Src_SrcA_SRC_Y	P04626	ERBB2	P12931	SRC	Y1005	D1012N	1012	Missense	distal	7	no	22.300	22.298	EPSD	COSMIC	20.673	Down-regulation
TK_Src_SrcA_SRC_Y	P04626	ERBB2	P12931	SRC	Y1023	F1030C	1030	Missense	distal	7	no	22.106	22.188	EPSD	COSMIC	20.673	Up-regulation
TK_Src_SrcA_SRC_Y	P04626	ERBB2	P12931	SRC	Y1023	F1030S	1030	Missense	distal	7	no	22.106	22.078	EPSD	COSMIC	20.673	Down-regulation
TK_Src_SrcA_SRC_Y	P04626	ERBB2	P12931	SRC	Y1023	Q1027E	1027	Missense	distal	4	no	22.106	22.098	EPSD	COSMIC	20.673	Down-regulation
TK_Src_SrcA_SRC_Y	P04626	ERBB2	P12931	SRC	Y1023	P1026S	1026	Missense	distal	3	no	22.106	21.367	EPSD	COSMIC	20.673	Down-regulation
TK_Src_SrcA_SRC_Y	P04626	ERBB2	P12931	SRC	Y1127	A1129V	1129	Missense	proximal	2	no	21.830	22.041	EPSD	COSMIC	20.673	Up-regulation
TK_Src_SrcA_SRC_Y	P04626	ERBB2	P12931	SRC	Y1127	D1125E	1125	Missense	proximal	-2	no	21.830	22.118	EPSD	COSMIC;GDSC	20.673	Up-regulation
TK_Src_SrcA_SRC_Y	P04626	ERBB2	P12931	SRC	Y1127	C1133S	1133	Missense	distal	6	no	21.830	21.755	EPSD	COSMIC	20.673	Down-regulation
TK_Src_SrcA_SRC_Y	P04626	ERBB2	P12931	SRC	Y1139	D1144N	1144	Missense	distal	5	no	21.461	21.619	EPSD	COSMIC	20.673	Up-regulation
TK_Src_SrcA_SRC_Y	P04626	ERBB2	P12931	SRC	Y1139	P1143T	1143	Missense	distal	4	no	21.461	21.477	EPSD	COSMIC	20.673	Up-regulation
TK_Src_SrcA_SRC_Y	P04626	ERBB2	P12931	SRC	Y1139	R1146W	1146	Missense	distal	7	no	21.461	21.558	EPSD	COSMIC;GDSC;CCLE	20.673	Up-regulation
TK_Src_SrcA_SRC_Y	P04626	ERBB2	P12931	SRC	Y1139	C1133S	1133	Missense	distal	-6	no	21.461	21.999	EPSD	COSMIC	20.673	Up-regulation
TK_Src_SrcA_SRC_Y	P04626	ERBB2	P12931	SRC	Y1139	D1144H	1144	Missense	distal	5	no	21.461	21.750	EPSD	COSMIC;GDSC	20.673	Up-regulation
TK_Src_SrcA_SRC_Y	P04626	ERBB2	P12931	SRC	Y1196	G1201V	1201	Missense	distal	5	no	22.534	22.425	EPSD	COSMIC	20.673	Down-regulation
TK_Src_SrcA_SRC_Y	P04626	ERBB2	P12931	SRC	Y1196	G1202V	1202	Missense	distal	6	no	22.534	22.528	EPSD	COSMIC	20.673	Down-regulation
TK_Src_SrcA_SRC_Y	P04626	ERBB2	P12931	SRC	Y1196	E1195K	1195	Missense	proximal	-1	no	22.534	20.626	EPSD	COSMIC	20.673	Loss
TK_Src_SrcA_SRC_Y	P04626	ERBB2	P12931	SRC	Y1196	L1197F	1197	Missense	proximal	1	no	22.534	22.203	EPSD	COSMIC	20.673	Down-regulation
TK_Src_SrcA_SRC_Y	P04626	ERBB2	P12931	SRC	Y1196	V1191M	1191	Missense	distal	-5	no	22.534	22.215	EPSD	COSMIC	20.673	Down-regulation
TK_Src_SrcA_SRC_Y	P04626	ERBB2	P12931	SRC	Y1196	Q1200H	1200	Missense	distal	4	no	22.534	22.526	EPSD	COSMIC	20.673	Down-regulation
TK_Src_SrcA_SRC_Y	P04626	ERBB2	P12931	SRC	Y1221	A1216D	1216	Missense	distal	-5	no	21.140	21.322	EPSD	COSMIC	20.673	Up-regulation
TK_Src_SrcA_SRC_Y	P04626	ERBB2	P12931	SRC	Y1221	P1227S	1227	Missense	distal	6	no	21.140	21.124	EPSD	COSMIC	20.673	Down-regulation
TK_Src_SrcA_SRC_Y	P04626	ERBB2	P12931	SRC	Y1248	G1250S	1250	Missense	proximal	2	no	19.902	21.030	EPSD	COSMIC	20.673	Gain
TK_Src_SrcA_SRC_Y	P19367	HK1	P12931	SRC	Y112	E110D	110	Missense	proximal	-2	no	24.626	24.339	EPSD	COSMIC	20.673	Down-regulation
TK_Src_SrcA_SRC_Y	P19367	HK1	P12931	SRC	Y112	P115T	115	Missense	distal	3	no	24.626	23.975	EPSD	COSMIC	20.673	Down-regulation
TK_Src_SrcA_SRC_Y	P19367	HK1	P12931	SRC	Y417	T419M	419	Missense	proximal	2	no	21.559	21.411	EPSD	COSMIC	20.673	Down-regulation
TK_Src_SrcA_SRC_Y	P19367	HK1	P12931	SRC	Y417	G414R	414	Missense	distal	-3	no	21.559	20.666	EPSD	COSMIC	20.673	Loss
TK_Src_SrcA_SRC_Y	P19367	HK1	P12931	SRC	Y417	S424F	424	Missense	distal	7	no	21.559	21.587	EPSD	COSMIC	20.673	Up-regulation
TK_Src_SrcA_SRC_Y	P19367	HK1	P12931	SRC	Y732	E731K	731	Missense	proximal	-1	no	20.803	18.895	PhosphoSitePlus	COSMIC	20.673	Loss
TK_Src_SrcA_SRC_Y	P19367	HK1	P12931	SRC	Y732	V729L	729	Missense	distal	-3	no	20.803	19.991	PhosphoSitePlus	COSMIC	20.673	Loss
TK_Src_SrcA_SRC_Y	P19367	HK1	P12931	SRC	Y732	G737W	737	Missense	distal	5	no	20.803	21.213	PhosphoSitePlus	COSMIC	20.673	Up-regulation
TK_Src_SrcA_SRC_Y	Q14247	CTTN	P12931	SRC	Y154	Y154C	154	Missense	central	0	yes	21.047	0.000	EPSD	COSMIC;CCLE	20.673	Loss
TK_Src_SrcA_SRC_Y	Q14247	CTTN	P12931	SRC	Y310	G311E	311	Missense	proximal	1	no	20.236	21.220	EPSD	COSMIC	20.673	Gain
TK_Src_SrcA_SRC_Y	Q14247	CTTN	P12931	SRC	Y334	V330E	330	Missense	distal	-4	no	20.212	21.461	EPSD;PhosphoSitePlus	COSMIC	20.673	Gain
TK_Src_SrcA_SRC_Y	Q14247	CTTN	P12931	SRC	Y421	V420I	420	Missense	proximal	-1	no	23.528	23.154	EPSD	COSMIC	20.673	Down-regulation
TK_Src_SrcA_SRC_Y	Q14247	CTTN	P12931	SRC	Y421	S426F	426	Missense	distal	5	no	23.528	23.778	EPSD	COSMIC	20.673	Up-regulation
TK_Src_SrcA_SRC_Y	Q14247	CTTN	P12931	SRC	Y446	T440P	440	Missense	distal	-6	no	24.431	24.434	EPSD	COSMIC	20.673	Up-regulation
TK_Src_SrcA_SRC_Y	Q14247	CTTN	P12931	SRC	Y446	P442L	442	Missense	distal	-4	no	24.431	23.796	EPSD	COSMIC	20.673	Down-regulation
TK_Src_SrcA_SRC_Y	Q14247	CTTN	P12931	SRC	Y446	E441K	441	Missense	distal	-5	no	24.431	23.855	EPSD	COSMIC	20.673	Down-regulation
TK_Src_SrcA_SRC_Y	Q14247	CTTN	P12931	SRC	Y446	V445M	445	Missense	proximal	-1	no	24.431	22.825	EPSD	COSMIC	20.673	Down-regulation
TK_Src_SrcA_SRC_Y	Q14247	CTTN	P12931	SRC	Y464	Y464C	464	Missense	central	0	yes	21.253	0.000	EPSD	COSMIC	20.673	Loss
TK_Src_SrcA_SRC_Y	Q14247	CTTN	P12931	SRC	Y464	A463T	463	Missense	proximal	-1	no	21.253	21.236	EPSD	COSMIC	20.673	Down-regulation
TK_Src_SrcA_SRC_Y	Q14247	CTTN	P12931	SRC	Y470	Y464C	464	Missense	distal	-6	no	24.053	23.520	EPSD;PhosphoSitePlus	COSMIC	20.673	Down-regulation
TK_Src_SrcA_SRC_Y	Q14247	CTTN	P12931	SRC	Y470	A463T	463	Missense	distal	-7	no	24.053	24.473	EPSD;PhosphoSitePlus	COSMIC	20.673	Up-regulation
TK_Src_SrcA_SRC_Y	Q14247	CTTN	P12931	SRC	Y470	P476L	476	Missense	distal	6	no	24.053	24.069	EPSD;PhosphoSitePlus	COSMIC;GDSC;CCLE	20.673	Up-regulation
TK_Src_SrcA_SRC_Y	P12830	CDH1	P12931	SRC	Y753	R749Q	749	Missense	distal	-4	no	23.287	22.908	EPSD	COSMIC	20.673	Down-regulation
TK_Src_SrcA_SRC_Y	P12830	CDH1	P12931	SRC	Y753	V752I	752	Missense	proximal	-1	no	23.287	22.912	EPSD	COSMIC	20.673	Down-regulation
TK_Src_SrcA_SRC_Y	P12830	CDH1	P12931	SRC	Y753	D756Y	756	Missense	distal	3	no	23.287	23.663	EPSD	COSMIC	20.673	Up-regulation
TK_Src_SrcA_SRC_Y	P12830	CDH1	P12931	SRC	Y754	R749Q	749	Missense	distal	-5	no	22.006	21.847	PhosphoSitePlus	COSMIC	20.673	Down-regulation
TK_Src_SrcA_SRC_Y	P12830	CDH1	P12931	SRC	Y754	V752I	752	Missense	proximal	-2	no	22.006	21.689	PhosphoSitePlus	COSMIC	20.673	Down-regulation
TK_Src_SrcA_SRC_Y	P12830	CDH1	P12931	SRC	Y754	D756Y	756	Missense	proximal	2	no	22.006	22.026	PhosphoSitePlus	COSMIC	20.673	Up-regulation
TK_Src_SrcA_SRC_Y	P12830	CDH1	P12931	SRC	Y755	R749Q	749	Missense	distal	-6	no	21.893	21.995	EPSD	COSMIC	20.673	Up-regulation
TK_Src_SrcA_SRC_Y	P12830	CDH1	P12931	SRC	Y755	V752I	752	Missense	distal	-3	no	21.893	20.787	EPSD	COSMIC	20.673	Down-regulation
TK_Src_SrcA_SRC_Y	P12830	CDH1	P12931	SRC	Y755	D756Y	756	Missense	proximal	1	no	21.893	21.494	EPSD	COSMIC	20.673	Down-regulation
TK_Src_SrcA_SRC_Y	P12830	CDH1	P12931	SRC	Y827	D834H	834	Missense	distal	7	no	23.234	23.289	EPSD	COSMIC	20.673	Up-regulation
TK_Src_SrcA_SRC_Y	P12830	CDH1	P12931	SRC	Y827	F833Y	833	Missense	distal	6	no	23.234	23.236	EPSD	COSMIC	20.673	Up-regulation
TK_Src_SrcA_SRC_Y	P12830	CDH1	P12931	SRC	Y827	P825L	825	Missense	proximal	-2	no	23.234	21.703	EPSD	COSMIC	20.673	Down-regulation
TK_Src_SrcA_SRC_Y	P12830	CDH1	P12931	SRC	Y827	D821N	821	Missense	distal	-6	no	23.234	23.044	EPSD	COSMIC	20.673	Down-regulation
TK_Src_SrcA_SRC_Y	P12830	CDH1	P12931	SRC	Y859	D858E	858	Missense	proximal	-1	no	21.785	22.694	EPSD	COSMIC	20.673	Up-regulation
TK_Src_SrcA_SRC_Y	P12830	CDH1	P12931	SRC	Y859	E852D	852	Missense	distal	-7	no	21.785	21.756	EPSD	COSMIC	20.673	Down-regulation
TK_Src_SrcA_SRC_Y	P12830	CDH1	P12931	SRC	Y859	S853P	853	Missense	distal	-6	no	21.785	21.735	EPSD	COSMIC	20.673	Down-regulation
TK_Src_SrcA_SRC_Y	P12830	CDH1	P12931	SRC	Y859	D854Y	854	Missense	distal	-5	no	21.785	21.161	EPSD	COSMIC	20.673	Down-regulation
TK_Src_SrcA_SRC_Y	P12830	CDH1	P12931	SRC	Y859	Y859C	859	Missense	central	0	yes	21.785	0.000	EPSD	COSMIC	20.673	Loss
TK_Src_SrcA_SRC_Y	P12830	CDH1	P12931	SRC	Y859	E852K	852	Missense	distal	-7	no	21.785	21.622	EPSD	COSMIC	20.673	Down-regulation
TK_Src_SrcA_SRC_Y	P12830	CDH1	P12931	SRC	Y859	Y861C	861	Missense	proximal	2	no	21.785	20.794	EPSD	COSMIC	20.673	Down-regulation
TK_Src_SrcA_SRC_Y	P12830	CDH1	P12931	SRC	Y859	Q857K	857	Missense	proximal	-2	no	21.785	21.615	EPSD	COSMIC	20.673	Down-regulation
TK_Src_SrcA_SRC_Y	Q9UGK3	STAP2	P12931	SRC	Y250	P243S	243	Missense	distal	-7	no	22.925	23.046	PhosphoSitePlus;EPSD	COSMIC	20.673	Up-regulation
TK_Src_SrcA_SRC_Y	Q96P31	FCRL3	P12931	SRC	Y133	D136N	136	Missense	distal	3	no	21.037	22.113	EPSD	COSMIC	20.673	Up-regulation
TK_Src_SrcA_SRC_Y	Q96P31	FCRL3	P12931	SRC	Y133	Q130E	130	Missense	distal	-3	no	21.037	21.917	EPSD	COSMIC	20.673	Up-regulation
TK_Src_SrcA_SRC_Y	Q96P31	FCRL3	P12931	SRC	Y133	D136Y	136	Missense	distal	3	no	21.037	21.413	EPSD	COSMIC	20.673	Up-regulation
TK_Src_SrcA_SRC_Y	Q96P31	FCRL3	P12931	SRC	Y650	M649T	649	Missense	proximal	-1	no	20.454	20.707	EPSD;PhosphoSitePlus	COSMIC	20.673	Gain
TK_Src_SrcA_SRC_Y	Q96P31	FCRL3	P12931	SRC	Y662	P655T	655	Missense	distal	-7	no	21.137	21.354	EPSD;PhosphoSitePlus	COSMIC	20.673	Up-regulation
TK_Src_SrcA_SRC_Y	Q96P31	FCRL3	P12931	SRC	Y662	W666C	666	Missense	distal	4	no	21.137	21.166	EPSD;PhosphoSitePlus	COSMIC	20.673	Up-regulation
TK_Src_SrcA_SRC_Y	Q96P31	FCRL3	P12931	SRC	Y722	E715G	715	Missense	distal	-7	no	22.894	22.443	PhosphoSitePlus;EPSD	COSMIC	20.673	Down-regulation
TK_Src_SrcA_SRC_Y	Q96P31	FCRL3	P12931	SRC	Y722	N724S	724	Missense	proximal	2	no	22.894	23.141	PhosphoSitePlus;EPSD	COSMIC	20.673	Up-regulation
TK_Src_SrcA_SRC_Y	Q96P31	FCRL3	P12931	SRC	Y722	P726Q	726	Missense	distal	4	no	22.894	22.911	PhosphoSitePlus;EPSD	COSMIC	20.673	Up-regulation
TK_Src_SrcA_SRC_Y	Q13642	FHL1	P12931	SRC	Y149	C153Y	153	Missense	distal	4	no	20.765	20.755	EPSD;PhosphoSitePlus	COSMIC	20.673	Down-regulation
TK_Src_SrcA_SRC_Y	Q13642	FHL1	P12931	SRC	Y176	Q179H	179	Missense	distal	3	no	21.239	22.016	EPSD	COSMIC	20.673	Up-regulation
TK_Src_SrcA_SRC_Y	Q13642	FHL1	P12931	SRC	Y176	G173E	173	Missense	distal	-3	no	21.239	21.842	EPSD	COSMIC	20.673	Up-regulation
TK_Src_SrcA_SRC_Y	Q13642	FHL1	P12931	SRC	Y207	D205H	205	Missense	proximal	-2	no	21.325	20.544	EPSD	COSMIC	20.673	Loss
TK_Src_SrcA_SRC_Y	Q13642	FHL1	P12931	SRC	Y208	D205H	205	Missense	distal	-3	no	22.496	20.919	EPSD	COSMIC	20.673	Down-regulation
TK_Src_SrcA_SRC_Y	P35222	CTNNB1	P12931	SRC	Y64	V62G	62	Missense	proximal	-2	no	20.218	21.495	EPSD	COSMIC	20.673	Gain
TK_Src_SrcA_SRC_Y	P35222	CTNNB1	P12931	SRC	Y64	E67N	67	Missense	distal	3	no	20.218	21.199	EPSD	COSMIC	20.673	Gain
TK_Src_SrcA_SRC_Y	P35222	CTNNB1	P12931	SRC	Y86	Y86H	86	Missense	central	0	yes	21.696	0.000	EPSD	COSMIC	20.673	Loss
TK_Src_SrcA_SRC_Y	P35222	CTNNB1	P12931	SRC	Y86	V79I	79	Missense	distal	-7	no	21.696	21.713	EPSD	COSMIC	20.673	Up-regulation
TK_Src_SrcA_SRC_Y	P35222	CTNNB1	P12931	SRC	Y86	R93S	93	Missense	distal	7	no	21.696	21.658	EPSD	COSMIC	20.673	Down-regulation
TK_Src_SrcA_SRC_Y	P35222	CTNNB1	P12931	SRC	Y86	D83N	83	Missense	distal	-3	no	21.696	21.188	EPSD	COSMIC	20.673	Down-regulation
TK_Src_SrcA_SRC_Y	P35222	CTNNB1	P12931	SRC	Y86	I82F	82	Missense	distal	-4	no	21.696	21.903	EPSD	COSMIC	20.673	Up-regulation
TK_Src_SrcA_SRC_Y	P35222	CTNNB1	P12931	SRC	Y86	M88V	88	Missense	proximal	2	no	21.696	21.962	EPSD	COSMIC	20.673	Up-regulation
TK_Src_SrcA_SRC_Y	P35222	CTNNB1	P12931	SRC	Y86	I82V	82	Missense	distal	-4	no	21.696	22.294	EPSD	COSMIC	20.673	Up-regulation
TK_Src_SrcA_SRC_Y	P35222	CTNNB1	P12931	SRC	Y333	L336V	336	Missense	distal	3	no	22.219	22.192	PhosphoSitePlus;EPSD	COSMIC	20.673	Down-regulation
TK_Src_SrcA_SRC_Y	P35222	CTNNB1	P12931	SRC	Y333	I327T	327	Missense	distal	-6	no	22.219	22.190	PhosphoSitePlus;EPSD	COSMIC	20.673	Down-regulation
TK_Src_SrcA_SRC_Y	P35222	CTNNB1	P12931	SRC	Y333	I327V	327	Missense	distal	-6	no	22.219	21.992	PhosphoSitePlus;EPSD	COSMIC	20.673	Down-regulation
TK_Src_SrcA_SRC_Y	P35222	CTNNB1	P12931	SRC	Y333	K335R	335	Missense	proximal	2	no	22.219	22.731	PhosphoSitePlus;EPSD	COSMIC	20.673	Up-regulation
TK_Src_SrcA_SRC_Y	P35222	CTNNB1	P12931	SRC	Y333	K335Q	335	Missense	proximal	2	no	22.219	23.080	PhosphoSitePlus;EPSD	COSMIC	20.673	Up-regulation
TK_Src_SrcA_SRC_Y	P35222	CTNNB1	P12931	SRC	Y333	L337P	337	Missense	distal	4	no	22.219	22.191	PhosphoSitePlus;EPSD	COSMIC	20.673	Down-regulation
TK_Src_SrcA_SRC_Y	P35222	CTNNB1	P12931	SRC	Y716	Y716C	716	Missense	central	0	yes	21.309	0.000	EPSD	COSMIC	20.673	Loss
TK_Src_SrcA_SRC_Y	P35222	CTNNB1	P12931	SRC	Y716	H720P	720	Missense	distal	4	no	21.309	21.301	EPSD	COSMIC	20.673	Down-regulation
TK_Src_SrcA_SRC_Y	P35222	CTNNB1	P12931	SRC	Y716	R717C	717	Missense	proximal	1	no	21.309	20.006	EPSD	COSMIC	20.673	Loss
TK_Src_SrcA_SRC_Y	P35222	CTNNB1	P12931	SRC	Y716	S715R	715	Missense	proximal	-1	no	21.309	19.995	EPSD	COSMIC	20.673	Loss
TK_Src_SrcA_SRC_Y	P35222	CTNNB1	P12931	SRC	Y716	D712N	712	Missense	distal	-4	no	21.309	20.777	EPSD	COSMIC	20.673	Down-regulation
TK_Src_SrcA_SRC_Y	P35222	CTNNB1	P12931	SRC	Y716	P714S	714	Missense	proximal	-2	no	21.309	20.523	EPSD	COSMIC	20.673	Loss
TK_Src_SrcA_SRC_Y	P35222	CTNNB1	P12931	SRC	Y716	Y709C	709	Missense	distal	-7	no	21.309	20.817	EPSD	COSMIC	20.673	Down-regulation
TK_Src_SrcA_SRC_Y	P35222	CTNNB1	P12931	SRC	Y716	R710C	710	Missense	distal	-6	no	21.309	20.913	EPSD	COSMIC	20.673	Down-regulation
TK_Src_SrcA_SRC_Y	P35222	CTNNB1	P12931	SRC	Y716	G723S	723	Missense	distal	7	no	21.309	21.278	EPSD	COSMIC	20.673	Down-regulation
TK_Src_SrcA_SRC_Y	P35222	CTNNB1	P12931	SRC	Y724	H720P	720	Missense	distal	-4	no	20.894	21.055	EPSD	COSMIC	20.673	Up-regulation
TK_Src_SrcA_SRC_Y	P35222	CTNNB1	P12931	SRC	Y724	A728T	728	Missense	distal	4	no	20.894	20.890	EPSD	COSMIC	20.673	Down-regulation
TK_Src_SrcA_SRC_Y	P35222	CTNNB1	P12931	SRC	Y724	D727H	727	Missense	distal	3	no	20.894	21.172	EPSD	COSMIC	20.673	Up-regulation
TK_Src_SrcA_SRC_Y	P35222	CTNNB1	P12931	SRC	Y724	R717C	717	Missense	distal	-7	no	20.894	19.753	EPSD	COSMIC	20.673	Loss
TK_Src_SrcA_SRC_Y	P35222	CTNNB1	P12931	SRC	Y724	G730S	730	Missense	distal	6	no	20.894	20.874	EPSD	COSMIC	20.673	Down-regulation
TK_Src_SrcA_SRC_Y	P35222	CTNNB1	P12931	SRC	Y724	Y724S	724	Missense	central	0	yes	20.894	0.000	EPSD	COSMIC	20.673	Loss
TK_Src_SrcA_SRC_Y	P35222	CTNNB1	P12931	SRC	Y724	L729F	729	Missense	distal	5	no	20.894	20.952	EPSD	COSMIC	20.673	Up-regulation
TK_Src_SrcA_SRC_Y	P35222	CTNNB1	P12931	SRC	Y724	G723S	723	Missense	proximal	-1	no	20.894	21.438	EPSD	COSMIC	20.673	Up-regulation
TK_Src_SrcA_SRC_Y	P35222	CTNNB1	P12931	SRC	Y724	D727A	727	Missense	distal	3	no	20.894	21.074	EPSD	COSMIC	20.673	Up-regulation
TK_Src_SrcA_SRC_Y	P35222	CTNNB1	P12931	SRC	Y724	Y724C	724	Missense	central	0	yes	20.894	0.000	EPSD	COSMIC	20.673	Loss
TK_Src_SrcA_SRC_Y	P35222	CTNNB1	P12931	SRC	Y724	G725D	725	Missense	proximal	1	no	20.894	21.272	EPSD	COSMIC	20.673	Up-regulation
TK_Src_SrcA_SRC_Y	P09327	VIL1	P12931	SRC	Y46	D42N	42	Missense	distal	-4	no	21.304	20.771	EPSD;PhosphoSitePlus	COSMIC	20.673	Down-regulation
TK_Src_SrcA_SRC_Y	P09327	VIL1	P12931	SRC	Y461	Q468K	468	Missense	distal	7	no	21.130	21.147	EPSD	COSMIC	20.673	Up-regulation
TK_Src_SrcA_SRC_Y	P09327	VIL1	P12931	SRC	Y461	Q462K	462	Missense	proximal	1	no	21.130	19.721	EPSD	COSMIC	20.673	Loss
TK_Src_SrcA_SRC_Y	P09327	VIL1	P12931	SRC	Y461	D454N	454	Missense	distal	-7	no	21.130	21.050	EPSD	COSMIC	20.673	Down-regulation
TK_Src_SrcA_SRC_Y	P09327	VIL1	P12931	SRC	Y461	I456T	456	Missense	distal	-5	no	21.130	21.128	EPSD	COSMIC	20.673	Down-regulation
TK_Src_SrcA_SRC_Y	O15162	PLSCR1	P12931	SRC	Y69	N70S	70	Missense	proximal	1	no	22.480	23.379	PhosphoSitePlus;EPSD	COSMIC	20.673	Up-regulation
TK_Src_SrcA_SRC_Y	O15162	PLSCR1	P12931	SRC	Y74	N70S	70	Missense	distal	-4	no	22.539	22.124	EPSD;PhosphoSitePlus	COSMIC	20.673	Down-regulation
TK_Src_SrcA_SRC_Y	P01889	HLA-B	P12931	SRC	Y344	C349W	349	Missense	distal	5	no	21.507	21.665	PhosphoSitePlus	COSMIC	20.673	Up-regulation
TK_Src_SrcA_SRC_Y	P01889	HLA-B	P12931	SRC	Y344	G338D	338	Missense	distal	-6	no	21.507	21.814	PhosphoSitePlus	COSMIC	20.673	Up-regulation
TK_Src_SrcA_SRC_Y	P01889	HLA-B	P12931	SRC	Y344	S345F	345	Missense	proximal	1	no	21.507	19.630	PhosphoSitePlus	COSMIC	20.673	Loss
TK_Src_SrcA_SRC_Y	P01889	HLA-B	P12931	SRC	Y344	G338C	338	Missense	distal	-6	no	21.507	21.113	PhosphoSitePlus	COSMIC	20.673	Down-regulation
TK_Src_SrcA_SRC_Y	Q9Y3Q4	HCN4	P12931	SRC	Y506	A507S	507	Missense	proximal	1	no	22.963	23.162	EPSD	COSMIC	20.673	Up-regulation
TK_Src_SrcA_SRC_Y	Q9Y3Q4	HCN4	P12931	SRC	Y506	G511S	511	Missense	distal	5	no	22.963	22.757	EPSD	COSMIC	20.673	Down-regulation
TK_Src_SrcA_SRC_Y	Q9Y3Q4	HCN4	P12931	SRC	Y531	V534G	534	Missense	distal	3	no	21.210	20.833	PhosphoSitePlus	COSMIC	20.673	Down-regulation
TK_Src_SrcA_SRC_Y	Q9Y3Q4	HCN4	P12931	SRC	Y537	V534G	534	Missense	distal	-3	no	21.034	22.310	EPSD	COSMIC	20.673	Up-regulation
TK_Src_SrcA_SRC_Y	Q9Y3Q4	HCN4	P12931	SRC	Y537	S539C	539	Missense	proximal	2	no	21.034	19.602	EPSD	COSMIC	20.673	Loss
TK_Src_SrcA_SRC_Y	P04083	ANXA1	P12931	SRC	Y39	V36E	36	Missense	distal	-3	no	19.934	21.813	EPSD	COSMIC;CCLE	20.673	Gain
TK_Src_SrcA_SRC_Y	P49279	SLC11A1	P12931	SRC	Y15	P21L	21	Missense	distal	6	no	23.138	23.154	PhosphoSitePlus	COSMIC	20.673	Up-regulation
TK_Src_SrcA_SRC_Y	P49279	SLC11A1	P12931	SRC	Y15	S11C	11	Missense	distal	-4	no	23.138	21.808	PhosphoSitePlus	COSMIC	20.673	Down-regulation
TK_Src_SrcA_SRC_Y	P49279	SLC11A1	P12931	SRC	Y15	S13F	13	Missense	proximal	-2	no	23.138	22.157	PhosphoSitePlus	COSMIC	20.673	Down-regulation
TK_Src_SrcA_SRC_Y	P48048	KCNJ1	P12931	SRC	Y337	K336E	336	Missense	proximal	-1	no	21.579	23.487	PhosphoSitePlus	COSMIC	20.673	Up-regulation
TK_Src_SrcA_SRC_Y	P48048	KCNJ1	P12931	SRC	Y337	H342Y	342	Missense	distal	5	no	21.579	21.863	PhosphoSitePlus	COSMIC	20.673	Up-regulation
TK_Src_SrcA_SRC_Y	P31431	SDC4	P12931	SRC	Y180	K173E	173	Missense	distal	-7	no	21.173	21.336	PhosphoSitePlus	COSMIC	20.673	Up-regulation
TK_Src_SrcA_SRC_Y	P01111	NRAS	P12931	SRC	Y32	V29L	29	Missense	distal	-3	no	20.815	20.003	PhosphoSitePlus	COSMIC	20.673	Loss
TK_Src_SrcA_SRC_Y	P01111	NRAS	P12931	SRC	Y32	D33E	33	Missense	proximal	1	no	20.815	21.421	PhosphoSitePlus	COSMIC	20.673	Up-regulation
TK_Src_SrcA_SRC_Y	P01111	NRAS	P12931	SRC	Y32	D30N	30	Missense	proximal	-2	no	20.815	20.535	PhosphoSitePlus	COSMIC	20.673	Loss
TK_Src_SrcA_SRC_Y	P01111	NRAS	P12931	SRC	Y32	D38N	38	Missense	distal	6	no	20.815	20.819	PhosphoSitePlus	COSMIC	20.673	Up-regulation
TK_Src_SrcA_SRC_Y	P01111	NRAS	P12931	SRC	Y32	P34R	34	Missense	proximal	2	no	20.815	20.591	PhosphoSitePlus	COSMIC	20.673	Loss
TK_Src_SrcA_SRC_Y	P01111	NRAS	P12931	SRC	Y64	G60E	60	Missense	distal	-4	no	23.002	23.435	EPSD	COSMIC	20.673	Up-regulation
TK_Src_SrcA_SRC_Y	P01111	NRAS	P12931	SRC	Y64	Q70H	70	Missense	distal	6	no	23.002	23.014	EPSD	COSMIC	20.673	Up-regulation
TK_Src_SrcA_SRC_Y	P01111	NRAS	P12931	SRC	Y64	E63K	63	Missense	proximal	-1	no	23.002	21.094	EPSD	COSMIC	20.673	Down-regulation
TK_Src_SrcA_SRC_Y	P01111	NRAS	P12931	SRC	Y64	E62Q	62	Missense	proximal	-2	no	23.002	21.812	EPSD	COSMIC	20.673	Down-regulation
TK_Src_SrcA_SRC_Y	P01111	NRAS	P12931	SRC	Y64	R68T	68	Missense	distal	4	no	23.002	23.022	EPSD	COSMIC;GDSC;CCLE	20.673	Up-regulation
TK_Src_SrcA_SRC_Y	P01111	NRAS	P12931	SRC	Y64	G60R	60	Missense	distal	-4	no	23.002	22.984	EPSD	COSMIC	20.673	Down-regulation
TK_Src_SrcA_SRC_Y	P01111	NRAS	P12931	SRC	Y64	Y64C	64	Missense	central	0	yes	23.002	0.000	EPSD	COSMIC	20.673	Loss
TK_Src_SrcA_SRC_Y	P01111	NRAS	P12931	SRC	Y64	D57E	57	Missense	distal	-7	no	23.002	23.031	EPSD	COSMIC	20.673	Up-regulation
TK_Src_SrcA_SRC_Y	P01111	NRAS	P12931	SRC	Y64	Y64D	64	Missense	central	0	yes	23.002	0.000	EPSD	COSMIC	20.673	Loss
TK_Src_SrcA_SRC_Y	P01111	NRAS	P12931	SRC	Y64	Q61E	61	Missense	distal	-3	no	23.002	23.882	EPSD	COSMIC	20.673	Up-regulation
TK_Src_SrcA_SRC_Y	P01111	NRAS	P12931	SRC	Y64	G60V	60	Missense	distal	-4	no	23.002	22.186	EPSD	COSMIC	20.673	Down-regulation
TK_Src_SrcA_SRC_Y	P01111	NRAS	P12931	SRC	Y64	Q61X	61	Missense	distal	-3	no	23.002	21.940	EPSD	COSMIC	20.673	Down-regulation
TK_Src_SrcA_SRC_Y	P01111	NRAS	P12931	SRC	Y64	S65C	65	Missense	proximal	1	no	23.002	20.819	EPSD	COSMIC	20.673	Down-regulation
TK_Src_SrcA_SRC_Y	P01111	NRAS	P12931	SRC	Y64	A59D	59	Missense	distal	-5	no	23.002	23.184	EPSD	COSMIC	20.673	Up-regulation
TK_Src_SrcA_SRC_Y	P01111	NRAS	P12931	SRC	Y64	Q61T	61	Missense	distal	-3	no	23.002	22.749	EPSD	COSMIC	20.673	Down-regulation
TK_Src_SrcA_SRC_Y	P01111	NRAS	P12931	SRC	Y64	A59G	59	Missense	distal	-5	no	23.002	23.032	EPSD	COSMIC	20.673	Up-regulation
TK_Src_SrcA_SRC_Y	P01111	NRAS	P12931	SRC	Y64	D57N	57	Missense	distal	-7	no	23.002	22.921	EPSD	COSMIC	20.673	Down-regulation
TK_Src_SrcA_SRC_Y	P01111	NRAS	P12931	SRC	Y64	Y64N	64	Missense	central	0	yes	23.002	0.000	EPSD	COSMIC	20.673	Loss
TK_Src_SrcA_SRC_Y	P01111	NRAS	P12931	SRC	Y64	S65R	65	Missense	proximal	1	no	23.002	22.123	EPSD	COSMIC	20.673	Down-regulation
TK_Src_SrcA_SRC_Y	P01111	NRAS	P12931	SRC	Y64	T58I	58	Missense	distal	-6	no	23.002	23.032	EPSD	COSMIC	20.673	Up-regulation
TK_Src_SrcA_SRC_Y	P01111	NRAS	P12931	SRC	Y64	E63G	63	Missense	proximal	-1	no	23.002	21.535	EPSD	COSMIC	20.673	Down-regulation
TK_Src_SrcA_SRC_Y	P01111	NRAS	P12931	SRC	Y64	S65N	65	Missense	proximal	1	no	23.002	22.103	EPSD	COSMIC	20.673	Down-regulation
TK_Src_SrcA_SRC_Y	P01111	NRAS	P12931	SRC	Y64	Q61S	61	Missense	distal	-3	no	23.002	23.459	EPSD	COSMIC	20.673	Up-regulation
TK_Src_SrcA_SRC_Y	P01111	NRAS	P12931	SRC	Y64	Y71C	71	Missense	distal	7	no	23.002	23.126	EPSD	COSMIC	20.673	Up-regulation
TK_Src_SrcA_SRC_Y	P01111	NRAS	P12931	SRC	Y64	M67I	67	Missense	distal	3	no	23.002	23.308	EPSD	COSMIC	20.673	Up-regulation
TK_Src_SrcA_SRC_Y	P01111	NRAS	P12931	SRC	Y64	A66T	66	Missense	proximal	2	no	23.002	23.095	EPSD	COSMIC	20.673	Up-regulation
TK_Src_SrcA_SRC_Y	P01111	NRAS	P12931	SRC	Y64	A59S	59	Missense	distal	-5	no	23.002	23.100	EPSD	COSMIC	20.673	Up-regulation
TK_Src_SrcA_SRC_Y	P01111	NRAS	P12931	SRC	Y64	R68S	68	Missense	distal	4	no	23.002	23.028	EPSD	COSMIC	20.673	Up-regulation
TK_Src_SrcA_SRC_Y	P01111	NRAS	P12931	SRC	Y157	D154G	154	Missense	distal	-3	no	21.101	20.452	EPSD	COSMIC	20.673	Loss
TK_Src_SrcA_SRC_Y	P01111	NRAS	P12931	SRC	Y157	E153A	153	Missense	distal	-4	no	21.101	19.985	EPSD	COSMIC	20.673	Loss
TK_Src_SrcA_SRC_Y	P01111	NRAS	P12931	SRC	Y157	D154H	154	Missense	distal	-3	no	21.101	19.524	EPSD	COSMIC	20.673	Loss
TK_Src_SrcA_SRC_Y	Q9NZQ3	NCKIPSD	P12931	SRC	Y85	L87V	87	Missense	proximal	2	no	20.967	21.889	EPSD	COSMIC	20.673	Up-regulation
TK_Src_SrcA_SRC_Y	Q9NZQ3	NCKIPSD	P12931	SRC	Y161	G155R	155	Missense	distal	-6	no	22.909	22.911	EPSD;PhosphoSitePlus	COSMIC	20.673	Up-regulation
TK_Src_SrcA_SRC_Y	Q9NZQ3	NCKIPSD	P12931	SRC	Y161	G158R	158	Missense	distal	-3	no	22.909	22.016	EPSD;PhosphoSitePlus	COSMIC	20.673	Down-regulation
TK_Src_SrcA_SRC_Y	Q9NZQ3	NCKIPSD	P12931	SRC	Y161	P164S	164	Missense	distal	3	no	22.909	22.170	EPSD;PhosphoSitePlus	COSMIC	20.673	Down-regulation
TK_Src_SrcA_SRC_Y	Q9NZQ3	NCKIPSD	P12931	SRC	Y161	P166T	166	Missense	distal	5	no	22.909	22.901	EPSD;PhosphoSitePlus	COSMIC	20.673	Down-regulation
TK_Src_SrcA_SRC_Y	Q9NZQ3	NCKIPSD	P12931	SRC	Y227	T225M	225	Missense	proximal	-2	no	21.295	20.197	PhosphoSitePlus;EPSD	COSMIC	20.673	Loss
TK_Src_SrcA_SRC_Y	Q68CZ2	TNS3	P12931	SRC	Y549	R551W	551	Missense	proximal	2	no	21.183	21.540	EPSD	COSMIC	20.673	Up-regulation
TK_Src_SrcA_SRC_Y	Q68CZ2	TNS3	P12931	SRC	Y549	P548S	548	Missense	proximal	-1	no	21.183	20.832	EPSD	COSMIC	20.673	Down-regulation
TK_Src_SrcA_SRC_Y	Q68CZ2	TNS3	P12931	SRC	Y549	R551L	551	Missense	proximal	2	no	21.183	20.951	EPSD	COSMIC	20.673	Down-regulation
TK_Src_SrcA_SRC_Y	Q68CZ2	TNS3	P12931	SRC	Y549	T554A	554	Missense	distal	5	no	21.183	20.969	EPSD	COSMIC	20.673	Down-regulation
TK_Src_SrcA_SRC_Y	Q68CZ2	TNS3	P12931	SRC	Y584	S582N	582	Missense	proximal	-2	no	20.260	20.882	EPSD	COSMIC	20.673	Gain
TK_Src_SrcA_SRC_Y	Q68CZ2	TNS3	P12931	SRC	Y1256	F1257L	1257	Missense	proximal	1	no	20.764	21.095	EPSD;PhosphoSitePlus	COSMIC	20.673	Up-regulation
TK_Src_SrcA_SRC_Y	P46937	YAP1	P12931	SRC	Y391	L386P	386	Missense	distal	-5	no	21.123	21.279	EPSD	COSMIC	20.673	Up-regulation
TK_Src_SrcA_SRC_Y	P46937	YAP1	P12931	SRC	Y391	T390I	390	Missense	proximal	-1	no	21.123	22.102	EPSD	COSMIC	20.673	Up-regulation
TK_Src_SrcA_SRC_Y	P46937	YAP1	P12931	SRC	Y391	F385L	385	Missense	distal	-6	no	21.123	21.190	EPSD	COSMIC	20.673	Up-regulation
TK_Src_SrcA_SRC_Y	P46937	YAP1	P12931	SRC	Y391	E396K	396	Missense	distal	5	no	21.123	21.155	EPSD	COSMIC	20.673	Up-regulation
TK_Src_SrcA_SRC_Y	P46937	YAP1	P12931	SRC	Y391	D395G	395	Missense	distal	4	no	21.123	21.083	EPSD	COSMIC	20.673	Down-regulation
TK_Src_SrcA_SRC_Y	Q9UKT4	FBXO5	P12931	SRC	Y142	E143V	143	Missense	proximal	1	no	21.247	19.365	PhosphoSitePlus	COSMIC	20.673	Loss
TK_Src_SrcA_SRC_Y	Q9UKT4	FBXO5	P12931	SRC	Y142	L141F	141	Missense	proximal	-1	no	21.247	20.387	PhosphoSitePlus	COSMIC	20.673	Loss
TK_Src_SrcA_SRC_Y	Q9UKT4	FBXO5	P12931	SRC	Y142	D144H	144	Missense	proximal	2	no	21.247	20.724	PhosphoSitePlus	COSMIC	20.673	Down-regulation
TK_Src_SrcA_SRC_Y	Q9UKT4	FBXO5	P12931	SRC	Y318	T323N	323	Missense	distal	5	no	21.250	21.079	EPSD	COSMIC	20.673	Down-regulation
TK_Src_SrcA_SRC_Y	Q9UKT4	FBXO5	P12931	SRC	Y318	R322G	322	Missense	distal	4	no	21.250	21.252	EPSD	COSMIC	20.673	Up-regulation
TK_Src_SrcA_SRC_Y	P08238	HSP90AB1	P12931	SRC	Y155	H149Y	149	Missense	distal	-6	no	23.633	23.803	EPSD	COSMIC	20.673	Up-regulation
TK_Src_SrcA_SRC_Y	P08238	HSP90AB1	P12931	SRC	Y155	D151N	151	Missense	distal	-4	no	23.633	23.101	EPSD	COSMIC	20.673	Down-regulation
TK_Src_SrcA_SRC_Y	P08238	HSP90AB1	P12931	SRC	Y192	L193I	193	Missense	proximal	1	no	20.852	20.955	EPSD	COSMIC	20.673	Up-regulation
TK_Src_SrcA_SRC_Y	P08238	HSP90AB1	P12931	SRC	Y192	E187A	187	Missense	distal	-5	no	20.852	20.569	EPSD	COSMIC	20.673	Loss
TK_Src_SrcA_SRC_Y	P08238	HSP90AB1	P12931	SRC	Y192	R197L	197	Missense	distal	5	no	20.852	21.019	EPSD	COSMIC	20.673	Up-regulation
TK_Src_SrcA_SRC_Y	P08238	HSP90AB1	P12931	SRC	Y301	T297A	297	Missense	distal	-4	no	23.893	23.619	PhosphoSitePlus	COSMIC	20.673	Down-regulation
TK_Src_SrcA_SRC_Y	P08238	HSP90AB1	P12931	SRC	Y305	W312R	312	Missense	distal	7	no	22.401	22.305	EPSD	COSMIC	20.673	Down-regulation
TK_Src_SrcA_SRC_Y	Q9NV92	NDFIP2	P12931	SRC	Y167	V173L	173	Missense	distal	6	no	26.825	26.843	PhosphoSitePlus;EPSD	COSMIC	20.673	Up-regulation
TK_Src_SrcA_SRC_Y	Q9NV92	NDFIP2	P12931	SRC	Y171	V173L	173	Missense	proximal	2	no	20.974	20.051	EPSD;PhosphoSitePlus	COSMIC	20.673	Loss
TK_Src_SrcA_SRC_Y	Q9NV92	NDFIP2	P12931	SRC	Y177	S182F	182	Missense	distal	5	no	20.623	20.872	EPSD	COSMIC	20.673	Gain
TK_Src_SrcA_SRC_Y	Q969T9	WBP2	P12931	SRC	Y143	P149L	149	Missense	distal	6	no	21.471	21.487	EPSD	COSMIC	20.673	Up-regulation
TK_Src_SrcA_SRC_Y	Q969T9	WBP2	P12931	SRC	Y143	Y147H	147	Missense	distal	4	no	21.471	21.493	EPSD	COSMIC	20.673	Up-regulation
TK_Src_SrcA_SRC_Y	Q969T9	WBP2	P12931	SRC	Y232	P237L	237	Missense	distal	5	no	20.903	20.918	EPSD	COSMIC	20.673	Up-regulation
TK_Src_SrcA_SRC_Y	P10398	ARAF	P12931	SRC	Y42	R36Q	36	Missense	distal	-6	no	22.899	23.001	EPSD	COSMIC	20.673	Up-regulation
TK_Src_SrcA_SRC_Y	P10398	ARAF	P12931	SRC	Y42	V35D	35	Missense	distal	-7	no	22.899	23.220	EPSD	COSMIC	20.673	Up-regulation
TK_Src_SrcA_SRC_Y	P10398	ARAF	P12931	SRC	Y155	V158F	158	Missense	distal	3	no	20.789	21.057	EPSD	COSMIC	20.673	Up-regulation
TK_Src_SrcA_SRC_Y	P10398	ARAF	P12931	SRC	Y155	L161M	161	Missense	distal	6	no	20.789	20.799	EPSD	COSMIC	20.673	Up-regulation
TK_Src_SrcA_SRC_Y	P10398	ARAF	P12931	SRC	Y301	P306T	306	Missense	distal	5	no	22.006	21.999	EPSD;PhosphoSitePlus	COSMIC	20.673	Down-regulation
TK_Src_SrcA_SRC_Y	P10398	ARAF	P12931	SRC	Y301	G295W	295	Missense	distal	-6	no	22.006	21.741	EPSD;PhosphoSitePlus	COSMIC	20.673	Down-regulation
TK_Src_SrcA_SRC_Y	P10398	ARAF	P12931	SRC	Y301	R297Q	297	Missense	distal	-4	no	22.006	21.627	EPSD;PhosphoSitePlus	COSMIC	20.673	Down-regulation
TK_Src_SrcA_SRC_Y	P10398	ARAF	P12931	SRC	Y301	R297W	297	Missense	distal	-4	no	22.006	20.634	EPSD;PhosphoSitePlus	COSMIC	20.673	Loss
TK_Src_SrcA_SRC_Y	P10398	ARAF	P12931	SRC	Y302	P306T	306	Missense	distal	4	no	23.384	23.400	PhosphoSitePlus;EPSD	COSMIC	20.673	Up-regulation
TK_Src_SrcA_SRC_Y	P10398	ARAF	P12931	SRC	Y302	G295W	295	Missense	distal	-7	no	23.384	23.533	PhosphoSitePlus;EPSD	COSMIC	20.673	Up-regulation
TK_Src_SrcA_SRC_Y	P10398	ARAF	P12931	SRC	Y302	R297Q	297	Missense	distal	-5	no	23.384	23.225	PhosphoSitePlus;EPSD	COSMIC	20.673	Down-regulation
TK_Src_SrcA_SRC_Y	P10398	ARAF	P12931	SRC	Y302	R297W	297	Missense	distal	-5	no	23.384	22.719	PhosphoSitePlus;EPSD	COSMIC	20.673	Down-regulation
TK_Src_SrcA_SRC_Y	P98175	RBM10	P12931	SRC	Y16	R21H	21	Missense	distal	5	no	22.309	22.414	EPSD;PhosphoSitePlus	COSMIC	20.673	Up-regulation
TK_Src_SrcA_SRC_Y	P98175	RBM10	P12931	SRC	Y16	R9H	9	Missense	distal	-7	no	22.309	22.014	EPSD;PhosphoSitePlus	COSMIC	20.673	Down-regulation
TK_Src_SrcA_SRC_Y	P98175	RBM10	P12931	SRC	Y16	D20N	20	Missense	distal	4	no	22.309	22.325	EPSD;PhosphoSitePlus	COSMIC	20.673	Up-regulation
TK_Src_SrcA_SRC_Y	P98175	RBM10	P12931	SRC	Y16	A18D	18	Missense	proximal	2	no	22.309	22.200	EPSD;PhosphoSitePlus	COSMIC	20.673	Down-regulation
TK_Src_SrcA_SRC_Y	P98175	RBM10	P12931	SRC	Y36	R37Q	37	Missense	proximal	1	no	20.980	21.973	EPSD	COSMIC	20.673	Up-regulation
TK_Src_SrcA_SRC_Y	P98175	RBM10	P12931	SRC	Y36	R42H	42	Missense	distal	6	no	20.980	21.009	EPSD	COSMIC;CCLE	20.673	Up-regulation
TK_Src_SrcA_SRC_Y	P98175	RBM10	P12931	SRC	Y36	Y36C	36	Missense	central	0	yes	20.980	0.000	EPSD	COSMIC	20.673	Loss
TK_Src_SrcA_SRC_Y	P98175	RBM10	P12931	SRC	Y36	R42G	42	Missense	distal	6	no	20.980	21.006	EPSD	COSMIC	20.673	Up-regulation
TK_Src_SrcA_SRC_Y	P98175	RBM10	P12931	SRC	Y36	R42C	42	Missense	distal	6	no	20.980	21.061	EPSD	COSMIC	20.673	Up-regulation
TK_Src_SrcA_SRC_Y	P98175	RBM10	P12931	SRC	Y36	R37L	37	Missense	proximal	1	no	20.980	20.313	EPSD	COSMIC	20.673	Loss
TK_Src_SrcA_SRC_Y	P98175	RBM10	P12931	SRC	Y48	P45T	45	Missense	distal	-3	no	20.514	20.921	EPSD	COSMIC	20.673	Gain
TK_Src_SrcA_SRC_Y	P98175	RBM10	P12931	SRC	Y57	E63D	63	Missense	distal	6	no	21.216	21.166	EPSD	COSMIC	20.673	Down-regulation
TK_Src_SrcA_SRC_Y	P98175	RBM10	P12931	SRC	Y70	E63D	63	Missense	distal	-7	no	22.513	22.484	EPSD	COSMIC	20.673	Down-regulation
TK_Src_SrcA_SRC_Y	P98175	RBM10	P12931	SRC	Y70	E67G	67	Missense	distal	-3	no	22.513	21.909	EPSD	COSMIC	20.673	Down-regulation
TK_Src_SrcA_SRC_Y	P98175	RBM10	P12931	SRC	Y70	E67K	67	Missense	distal	-3	no	22.513	20.801	EPSD	COSMIC	20.673	Down-regulation
TK_Src_SrcA_SRC_Y	P98175	RBM10	P12931	SRC	Y107	R103W	103	Missense	distal	-4	no	21.824	20.452	EPSD	COSMIC;CCLE	20.673	Loss
TK_Src_SrcA_SRC_Y	P98175	RBM10	P12931	SRC	Y107	E113G	113	Missense	distal	6	no	21.824	21.815	EPSD	COSMIC	20.673	Down-regulation
TK_Src_SrcA_SRC_Y	P98175	RBM10	P12931	SRC	Y107	D101Y	101	Missense	distal	-6	no	21.824	21.657	EPSD	COSMIC	20.673	Down-regulation
TK_Src_SrcA_SRC_Y	P98175	RBM10	P12931	SRC	Y107	R103Q	103	Missense	distal	-4	no	21.824	21.445	EPSD	COSMIC	20.673	Down-regulation
TK_Src_SrcA_SRC_Y	P98175	RBM10	P12931	SRC	Y107	G100A	100	Missense	distal	-7	no	21.824	21.874	EPSD	COSMIC	20.673	Up-regulation
TK_Src_SrcA_SRC_Y	P98175	RBM10	P12931	SRC	Y561	E559K	559	Missense	proximal	-2	no	21.534	20.174	EPSD	COSMIC	20.673	Loss
TK_Src_SrcA_SRC_Y	P98175	RBM10	P12931	SRC	Y561	Q563H	563	Missense	proximal	2	no	21.534	21.032	EPSD	COSMIC	20.673	Down-regulation
TK_Src_SrcA_SRC_Y	P98175	RBM10	P12931	SRC	Y825	Y825C	825	Missense	central	0	yes	20.859	0.000	EPSD	COSMIC	20.673	Loss
TK_Src_SrcA_SRC_Y	P98175	RBM10	P12931	SRC	Y825	P831S	831	Missense	distal	6	no	20.859	20.843	EPSD	COSMIC	20.673	Down-regulation
TK_Src_SrcA_SRC_Y	P98175	RBM10	P12931	SRC	Y825	A818V	818	Missense	distal	-7	no	20.859	20.911	EPSD	COSMIC	20.673	Up-regulation
TK_Src_SrcA_SRC_Y	P98175	RBM10	P12931	SRC	Y825	A819S	819	Missense	distal	-6	no	20.859	20.949	EPSD	COSMIC	20.673	Up-regulation
TK_Src_SrcA_SRC_Y	P98175	RBM10	P12931	SRC	Y825	R821H	821	Missense	distal	-4	no	20.859	20.375	EPSD	COSMIC	20.673	Loss
TK_Src_SrcA_SRC_Y	P98175	RBM10	P12931	SRC	Y825	R821C	821	Missense	distal	-4	no	20.859	19.260	EPSD	COSMIC	20.673	Loss
TK_Src_SrcA_SRC_Y	Q15642	TRIP10	P12931	SRC	Y190	R196H	196	Missense	distal	6	no	22.464	22.492	EPSD	COSMIC	20.673	Up-regulation
TK_Src_SrcA_SRC_Y	Q15642	TRIP10	P12931	SRC	Y527	E520D	520	Missense	distal	-7	no	23.906	23.877	EPSD	COSMIC	20.673	Down-regulation
TK_Src_SrcA_SRC_Y	Q15642	TRIP10	P12931	SRC	Y527	I526V	526	Missense	proximal	-1	no	23.906	24.280	EPSD	COSMIC	20.673	Up-regulation
TK_Src_SrcA_SRC_Y	Q15642	TRIP10	P12931	SRC	Y527	D523E	523	Missense	distal	-4	no	23.906	23.680	EPSD	COSMIC	20.673	Down-regulation
TK_Src_SrcA_SRC_Y	Q02153	GUCY1B1	P12931	SRC	Y192	K187N	187	Missense	distal	-5	no	23.946	24.209	PhosphoSitePlus	COSMIC	20.673	Up-regulation
TK_Src_SrcA_SRC_Y	Q02153	GUCY1B1	P12931	SRC	Y192	R197I	197	Missense	distal	5	no	23.946	24.068	PhosphoSitePlus	COSMIC	20.673	Up-regulation
TK_Src_SrcA_SRC_Y	Q02153	GUCY1B1	P12931	SRC	Y192	E189Q	189	Missense	distal	-3	no	23.946	23.066	PhosphoSitePlus	COSMIC	20.673	Down-regulation
TK_Src_SrcA_SRC_Y	Q02153	GUCY1B1	P12931	SRC	Y192	F191V	191	Missense	proximal	-1	no	23.946	25.915	PhosphoSitePlus	COSMIC;GDSC	20.673	Up-regulation
TK_Src_SrcA_SRC_Y	Q02153	GUCY1B1	P12931	SRC	Y192	F191L	191	Missense	proximal	-1	no	23.946	24.805	PhosphoSitePlus	COSMIC	20.673	Up-regulation
TK_Src_SrcA_SRC_Y	Q02153	GUCY1B1	P12931	SRC	Y192	R197K	197	Missense	distal	5	no	23.946	24.003	PhosphoSitePlus	COSMIC	20.673	Up-regulation
TK_Src_SrcA_SRC_Y	Q02153	GUCY1B1	P12931	SRC	Y192	R197G	197	Missense	distal	5	no	23.946	24.127	PhosphoSitePlus	COSMIC;GDSC	20.673	Up-regulation
TK_Src_SrcA_SRC_Y	P60953	CDC42	P12931	SRC	Y64	L70P	70	Missense	distal	6	no	21.957	21.941	PhosphoSitePlus	COSMIC	20.673	Down-regulation
TK_Src_SrcA_SRC_Y	P60953	CDC42	P12931	SRC	Y64	D57E	57	Missense	distal	-7	no	21.957	21.985	PhosphoSitePlus	COSMIC	20.673	Up-regulation
TK_Src_SrcA_SRC_Y	P60953	CDC42	P12931	SRC	Y64	T58A	58	Missense	distal	-6	no	21.957	21.919	PhosphoSitePlus	COSMIC	20.673	Down-regulation
TK_Src_SrcA_SRC_Y	P60953	CDC42	P12931	SRC	Y64	P69L	69	Missense	distal	5	no	21.957	21.971	PhosphoSitePlus	COSMIC	20.673	Up-regulation
TK_Src_SrcA_SRC_Y	P52566	ARHGDIB	P12931	SRC	Y153	F155S	155	Missense	proximal	2	no	23.618	25.038	EPSD;PhosphoSitePlus	COSMIC	20.673	Up-regulation
TK_Src_SrcA_SRC_Y	P52566	ARHGDIB	P12931	SRC	Y153	P158S	158	Missense	distal	5	no	23.618	23.440	EPSD;PhosphoSitePlus	COSMIC	20.673	Down-regulation
TK_Src_SrcA_SRC_Y	P52565	ARHGDIA	P12931	SRC	Y156	Y156C	156	Missense	central	0	yes	23.928	0.000	EPSD;PhosphoSitePlus	COSMIC	20.673	Loss
TK_Src_SrcA_SRC_Y	P07900	HSP90AA1	P12931	SRC	Y160	Y160C	160	Missense	central	0	yes	24.090	0.000	EPSD	COSMIC	20.673	Loss
TK_Src_SrcA_SRC_Y	P07900	HSP90AA1	P12931	SRC	Y160	K153N	153	Missense	distal	-7	no	24.090	24.144	EPSD	COSMIC	20.673	Up-regulation
TK_Src_SrcA_SRC_Y	P07900	HSP90AA1	P12931	SRC	Y197	R201G	201	Missense	distal	4	no	20.768	20.769	PhosphoSitePlus	COSMIC	20.673	Up-regulation
TK_Src_SrcA_SRC_Y	P07900	HSP90AA1	P12931	SRC	Y313	D319G	319	Missense	distal	6	no	22.272	22.313	EPSD	COSMIC	20.673	Up-regulation
TK_Src_SrcA_SRC_Y	P07900	HSP90AA1	P12931	SRC	Y438	N444T	444	Missense	distal	6	no	21.194	21.201	EPSD	COSMIC	20.673	Up-regulation
TK_Src_SrcA_SRC_Y	Q8IXH7	NELFCD	P12931	SRC	Y15	M10T	10	Missense	distal	-5	no	24.345	24.453	EPSD	COSMIC	20.673	Up-regulation
TK_Src_SrcA_SRC_Y	Q15417	CNN3	P12931	SRC	Y10	G7S	7	Missense	distal	-3	no	20.934	21.115	PhosphoSitePlus	COSMIC	20.673	Up-regulation
TK_Src_SrcA_SRC_Y	Q15417	CNN3	P12931	SRC	Y300	S298N	298	Missense	proximal	-2	no	20.411	21.034	EPSD	COSMIC	20.673	Gain
TK_Src_SrcA_SRC_Y	Q01844	EWSR1	P12931	SRC	Y278	G279R	279	Missense	proximal	1	no	21.957	20.964	PhosphoSitePlus	COSMIC	20.673	Down-regulation
TK_Src_SrcA_SRC_Y	Q01844	EWSR1	P12931	SRC	Y278	M275I	275	Missense	distal	-3	no	21.957	21.334	PhosphoSitePlus	COSMIC	20.673	Down-regulation
TK_Src_SrcA_SRC_Y	Q01844	EWSR1	P12931	SRC	Y364	D359N	359	Missense	distal	-5	no	21.140	20.928	EPSD	COSMIC	20.673	Down-regulation
TK_Src_SrcA_SRC_Y	Q01844	EWSR1	P12931	SRC	Y417	P421S	421	Missense	distal	4	no	21.618	21.640	EPSD	COSMIC	20.673	Up-regulation
TK_Src_SrcA_SRC_Y	Q01844	EWSR1	P12931	SRC	Y417	D412N	412	Missense	distal	-5	no	21.618	21.406	EPSD	COSMIC	20.673	Down-regulation
TK_Src_SrcA_SRC_Y	Q01844	EWSR1	P12931	SRC	Y417	T414A	414	Missense	distal	-3	no	21.618	21.424	EPSD	COSMIC	20.673	Down-regulation
TK_Src_SrcA_SRC_Y	Q8IXJ6	SIRT2	P12931	SRC	Y104	P99L	99	Missense	distal	-5	no	21.286	21.130	PhosphoSitePlus	COSMIC	20.673	Down-regulation
TK_Src_SrcA_SRC_Y	Q8IXJ6	SIRT2	P12931	SRC	Y191	F190V	190	Missense	proximal	-1	no	19.807	21.776	EPSD	COSMIC	20.673	Gain
TK_Src_SrcA_SRC_Y	P56945	BCAR1	P12931	SRC	Y12	V6M	6	Missense	distal	-6	no	20.696	20.405	EPSD	COSMIC	20.673	Loss
TK_Src_SrcA_SRC_Y	P56945	BCAR1	P12931	SRC	Y12	E17K	17	Missense	distal	5	no	20.696	20.728	EPSD	COSMIC	20.673	Up-regulation
TK_Src_SrcA_SRC_Y	P56945	BCAR1	P12931	SRC	Y12	P19Q	19	Missense	distal	7	no	20.696	20.671	EPSD	COSMIC	20.673	Loss
TK_Src_SrcA_SRC_Y	P56945	BCAR1	P12931	SRC	Y12	E17V	17	Missense	distal	5	no	20.696	20.744	EPSD	COSMIC	20.673	Up-regulation
TK_Src_SrcA_SRC_Y	P56945	BCAR1	P12931	SRC	Y12	A10V	10	Missense	proximal	-2	no	20.696	20.398	EPSD	COSMIC	20.673	Loss
TK_Src_SrcA_SRC_Y	P56945	BCAR1	P12931	SRC	Y12	A8V	8	Missense	distal	-4	no	20.696	20.562	EPSD	COSMIC	20.673	Loss
TK_Src_SrcA_SRC_Y	P56945	BCAR1	P12931	SRC	Y128	P133L	133	Missense	distal	5	no	23.967	23.982	PhosphoSitePlus	COSMIC	20.673	Up-regulation
TK_Src_SrcA_SRC_Y	P56945	BCAR1	P12931	SRC	Y128	Y128C	128	Missense	central	0	yes	23.967	0.000	PhosphoSitePlus	COSMIC	20.673	Loss
TK_Src_SrcA_SRC_Y	P56945	BCAR1	P12931	SRC	Y128	P135H	135	Missense	distal	7	no	23.967	23.972	PhosphoSitePlus	COSMIC	20.673	Up-regulation
TK_Src_SrcA_SRC_Y	P56945	BCAR1	P12931	SRC	Y128	P133T	133	Missense	distal	5	no	23.967	23.960	PhosphoSitePlus	COSMIC	20.673	Down-regulation
TK_Src_SrcA_SRC_Y	P56945	BCAR1	P12931	SRC	Y128	G126A	126	Missense	proximal	-2	no	23.967	22.988	PhosphoSitePlus	COSMIC;GDSC;CCLE	20.673	Down-regulation
TK_Src_SrcA_SRC_Y	P56945	BCAR1	P12931	SRC	Y128	P131L	131	Missense	distal	3	no	23.967	23.870	PhosphoSitePlus	COSMIC;GDSC	20.673	Down-regulation
TK_Src_SrcA_SRC_Y	P56945	BCAR1	P12931	SRC	Y128	P133H	133	Missense	distal	5	no	23.967	23.920	PhosphoSitePlus	COSMIC	20.673	Down-regulation
TK_Src_SrcA_SRC_Y	P56945	BCAR1	P12931	SRC	Y165	P171H	171	Missense	distal	6	no	21.792	21.799	EPSD	COSMIC	20.673	Up-regulation
TK_Src_SrcA_SRC_Y	P56945	BCAR1	P12931	SRC	Y165	D163E	163	Missense	proximal	-2	no	21.792	22.079	EPSD	COSMIC	20.673	Up-regulation
TK_Src_SrcA_SRC_Y	P56945	BCAR1	P12931	SRC	Y165	P158S	158	Missense	distal	-7	no	21.792	21.913	EPSD	COSMIC	20.673	Up-regulation
TK_Src_SrcA_SRC_Y	P56945	BCAR1	P12931	SRC	Y165	G170W	170	Missense	distal	5	no	21.792	22.202	EPSD	COSMIC	20.673	Up-regulation
TK_Src_SrcA_SRC_Y	P56945	BCAR1	P12931	SRC	Y165	Q166H	166	Missense	proximal	1	no	21.792	20.726	EPSD	COSMIC	20.673	Down-regulation
TK_Src_SrcA_SRC_Y	P56945	BCAR1	P12931	SRC	Y165	P168L	168	Missense	distal	3	no	21.792	21.694	EPSD	COSMIC	20.673	Down-regulation
TK_Src_SrcA_SRC_Y	P56945	BCAR1	P12931	SRC	Y165	A161V	161	Missense	distal	-4	no	21.792	21.658	EPSD	COSMIC	20.673	Down-regulation
TK_Src_SrcA_SRC_Y	P56945	BCAR1	P12931	SRC	Y165	G172A	172	Missense	distal	7	no	21.792	21.750	EPSD	COSMIC	20.673	Down-regulation
TK_Src_SrcA_SRC_Y	P56945	BCAR1	P12931	SRC	Y179	P174R	174	Missense	distal	-5	no	22.216	22.235	EPSD	COSMIC	20.673	Up-regulation
TK_Src_SrcA_SRC_Y	P56945	BCAR1	P12931	SRC	Y179	V181M	181	Missense	proximal	2	no	22.216	21.951	EPSD	COSMIC	20.673	Down-regulation
TK_Src_SrcA_SRC_Y	P56945	BCAR1	P12931	SRC	Y179	P183H	183	Missense	distal	4	no	22.216	22.225	EPSD	COSMIC	20.673	Up-regulation
TK_Src_SrcA_SRC_Y	P56945	BCAR1	P12931	SRC	Y179	A185V	185	Missense	distal	6	no	22.216	22.226	EPSD	COSMIC;CCLE	20.673	Up-regulation
TK_Src_SrcA_SRC_Y	P56945	BCAR1	P12931	SRC	Y179	A185S	185	Missense	distal	6	no	22.216	22.212	EPSD	COSMIC	20.673	Down-regulation
TK_Src_SrcA_SRC_Y	P56945	BCAR1	P12931	SRC	Y179	G186W	186	Missense	distal	7	no	22.216	22.320	EPSD	COSMIC	20.673	Up-regulation
TK_Src_SrcA_SRC_Y	P56945	BCAR1	P12931	SRC	Y179	G172A	172	Missense	distal	-7	no	22.216	22.266	EPSD	COSMIC	20.673	Up-regulation
TK_Src_SrcA_SRC_Y	P56945	BCAR1	P12931	SRC	Y192	G188W	188	Missense	distal	-4	no	22.760	21.369	EPSD	COSMIC	20.673	Down-regulation
TK_Src_SrcA_SRC_Y	P56945	BCAR1	P12931	SRC	Y192	A185V	185	Missense	distal	-7	no	22.760	22.811	EPSD	COSMIC;CCLE	20.673	Up-regulation
TK_Src_SrcA_SRC_Y	P56945	BCAR1	P12931	SRC	Y192	A185S	185	Missense	distal	-7	no	22.760	23.084	EPSD	COSMIC	20.673	Up-regulation
TK_Src_SrcA_SRC_Y	P56945	BCAR1	P12931	SRC	Y192	G186W	186	Missense	distal	-6	no	22.760	22.494	EPSD	COSMIC	20.673	Down-regulation
TK_Src_SrcA_SRC_Y	P56945	BCAR1	P12931	SRC	Y224	R217H	217	Missense	distal	-7	no	23.020	22.725	EPSD	COSMIC	20.673	Down-regulation
TK_Src_SrcA_SRC_Y	P56945	BCAR1	P12931	SRC	Y224	A227G	227	Missense	distal	3	no	23.020	23.213	EPSD	COSMIC	20.673	Up-regulation
TK_Src_SrcA_SRC_Y	P56945	BCAR1	P12931	SRC	Y224	A227V	227	Missense	distal	3	no	23.020	23.590	EPSD	COSMIC	20.673	Up-regulation
TK_Src_SrcA_SRC_Y	P56945	BCAR1	P12931	SRC	Y234	A227G	227	Missense	distal	-7	no	23.780	23.730	EPSD	COSMIC	20.673	Down-regulation
TK_Src_SrcA_SRC_Y	P56945	BCAR1	P12931	SRC	Y234	A227V	227	Missense	distal	-7	no	23.780	23.832	EPSD	COSMIC	20.673	Up-regulation
TK_Src_SrcA_SRC_Y	P56945	BCAR1	P12931	SRC	Y234	P237L	237	Missense	distal	3	no	23.780	23.682	EPSD	COSMIC	20.673	Down-regulation
TK_Src_SrcA_SRC_Y	P56945	BCAR1	P12931	SRC	Y249	Y249N	249	Missense	central	0	yes	24.404	0.000	EPSD	COSMIC	20.673	Loss
TK_Src_SrcA_SRC_Y	P56945	BCAR1	P12931	SRC	Y249	R255W	255	Missense	distal	6	no	24.404	24.507	EPSD	COSMIC;CCLE	20.673	Up-regulation
TK_Src_SrcA_SRC_Y	P56945	BCAR1	P12931	SRC	Y267	Y267N	267	Missense	central	0	yes	25.176	0.000	EPSD	COSMIC	20.673	Loss
TK_Src_SrcA_SRC_Y	P56945	BCAR1	P12931	SRC	Y267	M272V	272	Missense	distal	5	no	25.176	24.882	EPSD	COSMIC	20.673	Down-regulation
TK_Src_SrcA_SRC_Y	P56945	BCAR1	P12931	SRC	Y267	Q261H	261	Missense	distal	-6	no	25.176	25.041	EPSD	COSMIC	20.673	Down-regulation
TK_Src_SrcA_SRC_Y	P56945	BCAR1	P12931	SRC	Y267	A273V	273	Missense	distal	6	no	25.176	25.186	EPSD	COSMIC	20.673	Up-regulation
TK_Src_SrcA_SRC_Y	P56945	BCAR1	P12931	SRC	Y267	A273G	273	Missense	distal	6	no	25.176	25.192	EPSD	COSMIC	20.673	Up-regulation
TK_Src_SrcA_SRC_Y	P56945	BCAR1	P12931	SRC	Y287	R280G	280	Missense	distal	-7	no	25.071	24.450	EPSD	COSMIC	20.673	Down-regulation
TK_Src_SrcA_SRC_Y	P56945	BCAR1	P12931	SRC	Y287	R280Q	280	Missense	distal	-7	no	25.071	24.847	EPSD	COSMIC	20.673	Down-regulation
TK_Src_SrcA_SRC_Y	P56945	BCAR1	P12931	SRC	Y287	V289M	289	Missense	proximal	2	no	25.071	24.806	EPSD	COSMIC	20.673	Down-regulation
TK_Src_SrcA_SRC_Y	P56945	BCAR1	P12931	SRC	Y287	Y287C	287	Missense	central	0	yes	25.071	0.000	EPSD	COSMIC	20.673	Loss
TK_Src_SrcA_SRC_Y	P56945	BCAR1	P12931	SRC	Y306	A304T	304	Missense	proximal	-2	no	22.295	22.424	EPSD	COSMIC	20.673	Up-regulation
TK_Src_SrcA_SRC_Y	P56945	BCAR1	P12931	SRC	Y306	H303R	303	Missense	distal	-3	no	22.295	22.330	EPSD	COSMIC	20.673	Up-regulation
TK_Src_SrcA_SRC_Y	P56945	BCAR1	P12931	SRC	Y306	Y306H	306	Missense	central	0	yes	22.295	0.000	EPSD	COSMIC	20.673	Loss
TK_Src_SrcA_SRC_Y	P56945	BCAR1	P12931	SRC	Y327	R323L	323	Missense	distal	-4	no	24.751	23.794	EPSD	COSMIC	20.673	Down-regulation
TK_Src_SrcA_SRC_Y	P56945	BCAR1	P12931	SRC	Y362	A368V	368	Missense	distal	6	no	25.092	25.102	EPSD	COSMIC	20.673	Up-regulation
TK_Src_SrcA_SRC_Y	P56945	BCAR1	P12931	SRC	Y362	P356L	356	Missense	distal	-6	no	25.092	25.072	EPSD	COSMIC	20.673	Down-regulation
TK_Src_SrcA_SRC_Y	P56945	BCAR1	P12931	SRC	Y362	P357S	357	Missense	distal	-5	no	25.092	25.194	EPSD	COSMIC	20.673	Up-regulation
TK_Src_SrcA_SRC_Y	P56945	BCAR1	P12931	SRC	Y362	P357L	357	Missense	distal	-5	no	25.092	24.936	EPSD	COSMIC	20.673	Down-regulation
TK_Src_SrcA_SRC_Y	P56945	BCAR1	P12931	SRC	Y362	P365L	365	Missense	distal	3	no	25.092	24.995	EPSD	COSMIC	20.673	Down-regulation
TK_Src_SrcA_SRC_Y	P56945	BCAR1	P12931	SRC	Y372	A368V	368	Missense	distal	-4	no	22.367	22.234	EPSD	COSMIC	20.673	Down-regulation
TK_Src_SrcA_SRC_Y	P56945	BCAR1	P12931	SRC	Y372	P375L	375	Missense	distal	3	no	22.367	22.270	EPSD	COSMIC	20.673	Down-regulation
TK_Src_SrcA_SRC_Y	P56945	BCAR1	P12931	SRC	Y372	P375S	375	Missense	distal	3	no	22.367	21.629	EPSD	COSMIC	20.673	Down-regulation
TK_Src_SrcA_SRC_Y	P56945	BCAR1	P12931	SRC	Y372	D373N	373	Missense	proximal	1	no	22.367	20.976	EPSD	COSMIC	20.673	Down-regulation
TK_Src_SrcA_SRC_Y	P56945	BCAR1	P12931	SRC	Y372	P365L	365	Missense	distal	-7	no	22.367	22.252	EPSD	COSMIC	20.673	Down-regulation
TK_Src_SrcA_SRC_Y	P56945	BCAR1	P12931	SRC	Y372	R379W	379	Missense	distal	7	no	22.367	22.464	EPSD	COSMIC	20.673	Up-regulation
TK_Src_SrcA_SRC_Y	P56945	BCAR1	P12931	SRC	Y387	P383L	383	Missense	distal	-4	no	22.339	21.705	EPSD	COSMIC	20.673	Down-regulation
TK_Src_SrcA_SRC_Y	P56945	BCAR1	P12931	SRC	Y387	R391Q	391	Missense	distal	4	no	22.339	22.361	EPSD	COSMIC	20.673	Up-regulation
TK_Src_SrcA_SRC_Y	P56945	BCAR1	P12931	SRC	Y387	P381L	381	Missense	distal	-6	no	22.339	22.320	EPSD	COSMIC	20.673	Down-regulation
TK_Src_SrcA_SRC_Y	P56945	BCAR1	P12931	SRC	Y387	R393Q	393	Missense	distal	6	no	22.339	22.356	EPSD	COSMIC;GDSC	20.673	Up-regulation
TK_Src_SrcA_SRC_Y	P56945	BCAR1	P12931	SRC	Y387	R393L	393	Missense	distal	6	no	22.339	22.377	EPSD	COSMIC	20.673	Up-regulation
TK_Src_SrcA_SRC_Y	P56945	BCAR1	P12931	SRC	Y387	D388N	388	Missense	proximal	1	no	22.339	20.948	EPSD	COSMIC	20.673	Down-regulation
TK_Src_SrcA_SRC_Y	P56945	BCAR1	P12931	SRC	Y387	R391H	391	Missense	distal	4	no	22.339	22.353	EPSD	COSMIC	20.673	Up-regulation
TK_Src_SrcA_SRC_Y	P56945	BCAR1	P12931	SRC	Y387	R393W	393	Missense	distal	6	no	22.339	22.442	EPSD	COSMIC;GDSC	20.673	Up-regulation
TK_Src_SrcA_SRC_Y	P56945	BCAR1	P12931	SRC	Y387	P383S	383	Missense	distal	-4	no	22.339	22.392	EPSD	COSMIC	20.673	Up-regulation
TK_Src_SrcA_SRC_Y	P56945	BCAR1	P12931	SRC	Y387	R380Q	380	Missense	distal	-7	no	22.339	22.115	EPSD	COSMIC;GDSC;CCLE	20.673	Down-regulation
TK_Src_SrcA_SRC_Y	P56945	BCAR1	P12931	SRC	Y410	D406N	406	Missense	distal	-4	no	24.087	23.555	EPSD	COSMIC	20.673	Down-regulation
TK_Src_SrcA_SRC_Y	P56945	BCAR1	P12931	SRC	Y410	S407T	407	Missense	distal	-3	no	24.087	23.377	EPSD	COSMIC;GDSC;CCLE	20.673	Down-regulation
TK_Src_SrcA_SRC_Y	P56945	BCAR1	P12931	SRC	Y653	D650N	650	Missense	distal	-3	no	23.258	22.749	EPSD	COSMIC	20.673	Down-regulation
TK_Src_SrcA_SRC_Y	P56945	BCAR1	P12931	SRC	Y653	G651W	651	Missense	proximal	-2	no	23.258	20.950	EPSD	COSMIC	20.673	Down-regulation
TK_Src_SrcA_SRC_Y	P56945	BCAR1	P12931	SRC	Y653	N655S	655	Missense	proximal	2	no	23.258	23.505	EPSD	COSMIC	20.673	Up-regulation
TK_Src_SrcA_SRC_Y	P56945	BCAR1	P12931	SRC	Y653	E654K	654	Missense	proximal	1	no	23.258	20.863	EPSD	COSMIC	20.673	Down-regulation
TK_Src_SrcA_SRC_Y	P56945	BCAR1	P12931	SRC	Y664	D663E	663	Missense	proximal	-1	no	20.824	21.733	EPSD	COSMIC	20.673	Up-regulation
TK_Src_SrcA_SRC_Y	P56945	BCAR1	P12931	SRC	Y664	Y664C	664	Missense	central	0	yes	20.824	0.000	EPSD	COSMIC	20.673	Loss
TK_Src_SrcA_SRC_Y	P56945	BCAR1	P12931	SRC	Y664	E662K	662	Missense	proximal	-2	no	20.824	19.465	EPSD	COSMIC	20.673	Loss
TK_Src_SrcA_SRC_Y	P56945	BCAR1	P12931	SRC	Y664	D665E	665	Missense	proximal	1	no	20.824	21.430	EPSD	COSMIC	20.673	Up-regulation
TK_Src_SrcA_SRC_Y	P56945	BCAR1	P12931	SRC	Y664	M661I	661	Missense	distal	-3	no	20.824	20.201	EPSD	COSMIC	20.673	Loss
TK_Src_SrcA_SRC_Y	P56945	BCAR1	P12931	SRC	Y664	G671R	671	Missense	distal	7	no	20.824	20.831	EPSD	COSMIC	20.673	Up-regulation
TK_Src_SrcA_SRC_Y	P56945	BCAR1	P12931	SRC	Y664	Y666C	666	Missense	proximal	2	no	20.824	19.833	EPSD	COSMIC	20.673	Loss
TK_Src_SrcA_SRC_Y	P56945	BCAR1	P12931	SRC	Y666	D665E	665	Missense	proximal	-1	no	19.820	20.730	EPSD	COSMIC	20.673	Gain
TK_Src_SrcA_SRC_Y	Q05655	PRKCD	P12931	SRC	Y64	V68I	68	Missense	distal	4	no	21.321	21.333	EPSD	COSMIC	20.673	Up-regulation
TK_Src_SrcA_SRC_Y	Q05655	PRKCD	P12931	SRC	Y64	R67S	67	Missense	distal	3	no	21.321	22.369	EPSD	COSMIC	20.673	Up-regulation
TK_Src_SrcA_SRC_Y	Q05655	PRKCD	P12931	SRC	Y313	S307L	307	Missense	distal	-6	no	23.323	23.254	PhosphoSitePlus;EPSD	COSMIC;GDSC;CCLE	20.673	Down-regulation
TK_Src_SrcA_SRC_Y	Q05655	PRKCD	P12931	SRC	Y313	S306Y	306	Missense	distal	-7	no	23.323	22.921	PhosphoSitePlus;EPSD	COSMIC;GDSC;CCLE	20.673	Down-regulation
TK_Src_SrcA_SRC_Y	Q05655	PRKCD	P12931	SRC	Y313	E317K	317	Missense	distal	4	no	23.323	23.324	PhosphoSitePlus;EPSD	COSMIC	20.673	Up-regulation
TK_Src_SrcA_SRC_Y	Q05655	PRKCD	P12931	SRC	Y334	M327L	327	Missense	distal	-7	no	20.833	21.139	EPSD;PhosphoSitePlus	COSMIC	20.673	Up-regulation
TK_Src_SrcA_SRC_Y	Q05655	PRKCD	P12931	SRC	Y334	S341N	341	Missense	distal	7	no	20.833	20.801	EPSD;PhosphoSitePlus	COSMIC	20.673	Down-regulation
TK_Src_SrcA_SRC_Y	Q05655	PRKCD	P12931	SRC	Y514	P517S	517	Missense	distal	3	no	21.007	20.268	EPSD	COSMIC	20.673	Loss
TK_Src_SrcA_SRC_Y	Q05655	PRKCD	P12931	SRC	Y567	R561P	561	Missense	distal	-6	no	21.050	21.141	EPSD	COSMIC	20.673	Up-regulation
TK_Src_SrcA_SRC_Y	Q05655	PRKCD	P12931	SRC	Y567	R569C	569	Missense	proximal	2	no	21.050	20.450	EPSD	COSMIC	20.673	Loss
TK_Src_SrcA_SRC_Y	Q05655	PRKCD	P12931	SRC	Y567	P568A	568	Missense	proximal	1	no	21.050	22.996	EPSD	COSMIC	20.673	Up-regulation
TK_Src_SrcA_SRC_Y	P42229	STAT5A	P12931	SRC	Y683	P685H	685	Missense	proximal	2	no	20.697	20.321	EPSD	COSMIC	20.673	Loss
TK_Src_SrcA_SRC_Y	P42229	STAT5A	P12931	SRC	Y683	Y682C	682	Missense	proximal	-1	no	20.697	19.628	EPSD	COSMIC	20.673	Loss
TK_Src_SrcA_SRC_Y	P42229	STAT5A	P12931	SRC	Y683	A688D	688	Missense	distal	5	no	20.697	20.583	EPSD	COSMIC	20.673	Loss
TK_Src_SrcA_SRC_Y	P46527	CDKN1B	P12931	SRC	Y74	G72A	72	Missense	proximal	-2	no	21.499	20.520	EPSD;PhosphoSitePlus	COSMIC	20.673	Loss
TK_Src_SrcA_SRC_Y	P46527	CDKN1B	P12931	SRC	Y74	E71K	71	Missense	distal	-3	no	21.499	19.788	EPSD;PhosphoSitePlus	COSMIC	20.673	Loss
TK_Src_SrcA_SRC_Y	P46527	CDKN1B	P12931	SRC	Y74	L70R	70	Missense	distal	-4	no	21.499	22.457	EPSD;PhosphoSitePlus	COSMIC	20.673	Up-regulation
TK_Src_SrcA_SRC_Y	P46527	CDKN1B	P12931	SRC	Y74	P69L	69	Missense	distal	-5	no	21.499	21.343	EPSD;PhosphoSitePlus	COSMIC	20.673	Down-regulation
TK_Src_SrcA_SRC_Y	P46527	CDKN1B	P12931	SRC	Y74	E80Q	80	Missense	distal	6	no	21.499	21.481	EPSD;PhosphoSitePlus	COSMIC	20.673	Down-regulation
TK_Src_SrcA_SRC_Y	P46527	CDKN1B	P12931	SRC	Y74	W76G	76	Missense	proximal	2	no	21.499	20.846	EPSD;PhosphoSitePlus	COSMIC	20.673	Down-regulation
TK_Src_SrcA_SRC_Y	P46527	CDKN1B	P12931	SRC	Y88	P91S	91	Missense	distal	3	no	21.012	20.273	EPSD;PhosphoSitePlus	COSMIC	20.673	Loss
TK_Src_SrcA_SRC_Y	P46527	CDKN1B	P12931	SRC	Y88	R90K	90	Missense	proximal	2	no	21.012	20.500	EPSD;PhosphoSitePlus	COSMIC	20.673	Loss
TK_Src_SrcA_SRC_Y	P46527	CDKN1B	P12931	SRC	Y88	R93W	93	Missense	distal	5	no	21.012	21.603	EPSD;PhosphoSitePlus	COSMIC	20.673	Up-regulation
TK_Src_SrcA_SRC_Y	P46527	CDKN1B	P12931	SRC	Y88	P94L	94	Missense	distal	6	no	21.012	21.028	EPSD;PhosphoSitePlus	COSMIC	20.673	Up-regulation
TK_Src_SrcA_SRC_Y	P46527	CDKN1B	P12931	SRC	Y88	Y88C	88	Missense	central	0	yes	21.012	0.000	EPSD;PhosphoSitePlus	COSMIC	20.673	Loss
TK_Src_SrcA_SRC_Y	P46527	CDKN1B	P12931	SRC	Y89	P91S	91	Missense	proximal	2	no	22.542	23.149	PhosphoSitePlus;EPSD	COSMIC	20.673	Up-regulation
TK_Src_SrcA_SRC_Y	P46527	CDKN1B	P12931	SRC	Y89	R90K	90	Missense	proximal	1	no	22.542	22.125	PhosphoSitePlus;EPSD	COSMIC	20.673	Down-regulation
TK_Src_SrcA_SRC_Y	P46527	CDKN1B	P12931	SRC	Y89	R93W	93	Missense	distal	4	no	22.542	22.514	PhosphoSitePlus;EPSD	COSMIC	20.673	Down-regulation
TK_Src_SrcA_SRC_Y	P46527	CDKN1B	P12931	SRC	Y89	P94L	94	Missense	distal	5	no	22.542	22.557	PhosphoSitePlus;EPSD	COSMIC	20.673	Up-regulation
TK_Src_SrcA_SRC_Y	P46527	CDKN1B	P12931	SRC	Y89	Y88C	88	Missense	proximal	-1	no	22.542	21.473	PhosphoSitePlus;EPSD	COSMIC	20.673	Down-regulation
TK_Src_SrcA_SRC_Y	Q96AC1	FERMT2	P12931	SRC	Y179	I178M	178	Missense	proximal	-1	no	23.819	22.588	EPSD	COSMIC	20.673	Down-regulation
TK_Src_SrcA_SRC_Y	Q96AE4	FUBP1	P12931	SRC	Y58	T51A	51	Missense	distal	-7	no	21.958	21.538	EPSD;PhosphoSitePlus	COSMIC	20.673	Down-regulation
TK_Src_SrcA_SRC_Y	Q96AE4	FUBP1	P12931	SRC	Y58	Q63K	63	Missense	distal	5	no	21.958	21.990	EPSD;PhosphoSitePlus	COSMIC	20.673	Up-regulation
TK_Src_SrcA_SRC_Y	Q96AE4	FUBP1	P12931	SRC	Y105	E104Q	104	Missense	proximal	-1	no	21.114	20.708	EPSD	COSMIC	20.673	Down-regulation
TK_Src_SrcA_SRC_Y	Q96AE4	FUBP1	P12931	SRC	Y105	M101I	101	Missense	distal	-4	no	21.114	20.942	EPSD	COSMIC	20.673	Down-regulation
TK_Src_SrcA_SRC_Y	Q96AE4	FUBP1	P12931	SRC	Y105	P108L	108	Missense	distal	3	no	21.114	21.016	EPSD	COSMIC	20.673	Down-regulation
TK_Src_SrcA_SRC_Y	Q96AE4	FUBP1	P12931	SRC	Y105	E104G	104	Missense	proximal	-1	no	21.114	19.647	EPSD	COSMIC	20.673	Loss
TK_Src_SrcA_SRC_Y	Q96AE4	FUBP1	P12931	SRC	Y105	S99Y	99	Missense	distal	-6	no	21.114	21.110	EPSD	COSMIC	20.673	Down-regulation
TK_Src_SrcA_SRC_Y	Q96AE4	FUBP1	P12931	SRC	Y590	A596T	596	Missense	distal	6	no	21.333	21.319	EPSD	COSMIC	20.673	Down-regulation
TK_Src_SrcA_SRC_Y	Q96AE4	FUBP1	P12931	SRC	Y611	P605L	605	Missense	distal	-6	no	21.502	21.482	EPSD	COSMIC	20.673	Down-regulation
TK_Src_SrcA_SRC_Y	Q96AE4	FUBP1	P12931	SRC	Y611	W615C	615	Missense	distal	4	no	21.502	21.531	EPSD	COSMIC	20.673	Up-regulation
TK_Src_SrcA_SRC_Y	Q96AE4	FUBP1	P12931	SRC	Y611	P605S	605	Missense	distal	-6	no	21.502	21.551	EPSD	COSMIC	20.673	Up-regulation
TK_Src_SrcA_SRC_Y	P55211	CASP9	P12931	SRC	Y251	Y251C	251	Missense	central	0	yes	22.764	0.000	PhosphoSitePlus	COSMIC	20.673	Loss
TK_Src_SrcA_SRC_Y	P55211	CASP9	P12931	SRC	Y251	G252S	252	Missense	proximal	1	no	22.764	22.649	PhosphoSitePlus	COSMIC	20.673	Down-regulation
TK_Src_SrcA_SRC_Y	P55211	CASP9	P12931	SRC	Y251	Q245P	245	Missense	distal	-6	no	22.764	22.752	PhosphoSitePlus	COSMIC	20.673	Down-regulation
TK_Src_SrcA_SRC_Y	P55211	CASP9	P12931	SRC	Y251	G252D	252	Missense	proximal	1	no	22.764	23.141	PhosphoSitePlus	COSMIC	20.673	Up-regulation
TK_Src_SrcA_SRC_Y	O95297	MPZL1	P12931	SRC	Y263	N256S	256	Missense	distal	-7	no	21.164	21.196	PhosphoSitePlus;EPSD	COSMIC	20.673	Up-regulation
TK_Src_SrcA_SRC_Y	O95297	MPZL1	P12931	SRC	Y263	E259K	259	Missense	distal	-4	no	21.164	19.994	PhosphoSitePlus;EPSD	COSMIC	20.673	Loss
TK_Src_SrcA_SRC_Y	Q96KB5	PBK	P12931	SRC	Y271	D267E	267	Missense	distal	-4	no	24.362	24.136	EPSD	COSMIC	20.673	Down-regulation
TK_Src_SrcA_SRC_Y	Q96KB5	PBK	P12931	SRC	Y272	P279S	279	Missense	distal	7	no	23.975	23.956	EPSD;PhosphoSitePlus	COSMIC	20.673	Down-regulation
TK_Src_SrcA_SRC_Y	Q96KB5	PBK	P12931	SRC	Y272	P279L	279	Missense	distal	7	no	23.975	23.969	EPSD;PhosphoSitePlus	COSMIC	20.673	Down-regulation
TK_Src_SrcA_SRC_Y	Q96KB5	PBK	P12931	SRC	Y272	D267E	267	Missense	distal	-5	no	23.975	24.076	EPSD;PhosphoSitePlus	COSMIC	20.673	Up-regulation
TK_Src_SrcA_SRC_Y	Q9NPY3	CD93	P12931	SRC	Y628	A625S	625	Missense	distal	-3	no	21.340	22.245	EPSD;PhosphoSitePlus	COSMIC	20.673	Up-regulation
TK_Src_SrcA_SRC_Y	Q9NPY3	CD93	P12931	SRC	Y628	R634Q	634	Missense	distal	6	no	21.340	21.356	EPSD;PhosphoSitePlus	COSMIC;CCLE	20.673	Up-regulation
TK_Src_SrcA_SRC_Y	Q9NPY3	CD93	P12931	SRC	Y628	Q622H	622	Missense	distal	-6	no	21.340	21.205	EPSD;PhosphoSitePlus	COSMIC	20.673	Down-regulation
TK_Src_SrcA_SRC_Y	P05106	ITGB3	P12931	SRC	Y773	A776V	776	Missense	distal	3	no	20.548	21.118	PhosphoSitePlus;EPSD	COSMIC	20.673	Gain
TK_Src_SrcA_SRC_Y	Q9H7P9	PLEKHG2	P12931	SRC	Y489	P484L	484	Missense	distal	-5	no	21.853	21.697	PhosphoSitePlus	COSMIC;GDSC;CCLE	20.673	Down-regulation
TK_Src_SrcA_SRC_Y	Q9H7P9	PLEKHG2	P12931	SRC	Y489	A496T	496	Missense	distal	7	no	21.853	21.834	PhosphoSitePlus	COSMIC;GDSC	20.673	Down-regulation
TK_Src_SrcA_SRC_Y	Q9H7P9	PLEKHG2	P12931	SRC	Y489	P493S	493	Missense	distal	4	no	21.853	21.875	PhosphoSitePlus	COSMIC	20.673	Up-regulation
TK_Src_SrcA_SRC_Y	Q9H7P9	PLEKHG2	P12931	SRC	Y489	V485M	485	Missense	distal	-4	no	21.853	21.428	PhosphoSitePlus	COSMIC	20.673	Down-regulation
TK_Src_SrcA_SRC_Y	Q9NPF5	DMAP1	P12931	SRC	Y58	A59T	59	Missense	proximal	1	no	21.313	20.859	EPSD	COSMIC	20.673	Down-regulation
TK_Src_SrcA_SRC_Y	O15056	SYNJ2	P12931	SRC	Y490	D496E	496	Missense	distal	6	no	22.663	22.713	PhosphoSitePlus	COSMIC	20.673	Up-regulation
TK_Src_SrcA_SRC_Y	O15056	SYNJ2	P12931	SRC	Y490	E493K	493	Missense	distal	3	no	22.663	21.326	PhosphoSitePlus	COSMIC	20.673	Down-regulation
TK_Src_SrcA_SRC_Y	O15056	SYNJ2	P12931	SRC	Y1136	H1133Q	1133	Missense	distal	-3	no	20.704	21.356	EPSD	COSMIC	20.673	Up-regulation
TK_Src_SrcA_SRC_Y	Q99704	DOK1	P12931	SRC	Y146	E142Q	142	Missense	distal	-4	no	21.479	20.649	EPSD	COSMIC	20.673	Loss
TK_Src_SrcA_SRC_Y	Q99704	DOK1	P12931	SRC	Y315	D320N	320	Missense	distal	5	no	21.446	21.604	EPSD	COSMIC	20.673	Up-regulation
TK_Src_SrcA_SRC_Y	Q99704	DOK1	P12931	SRC	Y337	K334Q	334	Missense	distal	-3	no	20.863	21.694	EPSD	COSMIC	20.673	Up-regulation
TK_Src_SrcA_SRC_Y	Q99704	DOK1	P12931	SRC	Y337	A344V	344	Missense	distal	7	no	20.863	20.939	EPSD	COSMIC	20.673	Up-regulation
TK_Src_SrcA_SRC_Y	Q99704	DOK1	P12931	SRC	Y362	G367C	367	Missense	distal	5	no	25.224	25.476	PhosphoSitePlus	COSMIC	20.673	Up-regulation
TK_Src_SrcA_SRC_Y	Q99704	DOK1	P12931	SRC	Y377	G375V	375	Missense	proximal	-2	no	22.425	21.149	EPSD	COSMIC	20.673	Down-regulation
TK_Src_SrcA_SRC_Y	Q99704	DOK1	P12931	SRC	Y377	P373L	373	Missense	distal	-4	no	22.425	21.790	EPSD	COSMIC	20.673	Down-regulation
TK_Src_SrcA_SRC_Y	Q99704	DOK1	P12931	SRC	Y398	V393L	393	Missense	distal	-5	no	22.688	22.527	EPSD	COSMIC	20.673	Down-regulation
TK_Src_SrcA_SRC_Y	Q99704	DOK1	P12931	SRC	Y409	P414S	414	Missense	distal	5	no	21.550	21.373	EPSD	COSMIC	20.673	Down-regulation
TK_Src_SrcA_SRC_Y	Q99704	DOK1	P12931	SRC	Y409	R415Q	415	Missense	distal	6	no	21.550	21.567	EPSD	COSMIC	20.673	Up-regulation
TK_Src_SrcA_SRC_Y	Q99704	DOK1	P12931	SRC	Y409	A410D	410	Missense	proximal	1	no	21.550	22.241	EPSD	COSMIC	20.673	Up-regulation
TK_Src_SrcA_SRC_Y	Q99704	DOK1	P12931	SRC	Y409	A410T	410	Missense	proximal	1	no	21.550	21.095	EPSD	COSMIC	20.673	Down-regulation
TK_Src_SrcA_SRC_Y	Q99704	DOK1	P12931	SRC	Y409	P413L	413	Missense	distal	4	no	21.550	21.578	EPSD	COSMIC	20.673	Up-regulation
TK_Src_SrcA_SRC_Y	Q99704	DOK1	P12931	SRC	Y409	R415W	415	Missense	distal	6	no	21.550	21.652	EPSD	COSMIC	20.673	Up-regulation
TK_Src_SrcA_SRC_Y	Q99704	DOK1	P12931	SRC	Y409	V411M	411	Missense	proximal	2	no	21.550	21.285	EPSD	COSMIC	20.673	Down-regulation
TK_Src_SrcA_SRC_Y	Q99704	DOK1	P12931	SRC	Y449	H444D	444	Missense	distal	-5	no	23.467	23.426	EPSD	COSMIC	20.673	Down-regulation
TK_Src_SrcA_SRC_Y	Q99704	DOK1	P12931	SRC	Y449	A447V	447	Missense	proximal	-2	no	23.467	23.170	EPSD	COSMIC	20.673	Down-regulation
TK_Src_SrcA_SRC_Y	P51692	STAT5B	P12931	SRC	Y668	R673W	673	Missense	distal	5	no	20.219	20.811	EPSD	COSMIC	20.673	Gain
TK_Src_SrcA_SRC_Y	P51692	STAT5B	P12931	SRC	Y668	G661R	661	Missense	distal	-7	no	20.219	20.840	EPSD	COSMIC	20.673	Gain
TK_Src_SrcA_SRC_Y	P51692	STAT5B	P12931	SRC	Y679	R673W	673	Missense	distal	-6	no	23.363	23.095	EPSD	COSMIC	20.673	Down-regulation
TK_Src_SrcA_SRC_Y	P51692	STAT5B	P12931	SRC	Y699	G698E	698	Missense	proximal	-1	no	20.320	21.786	PhosphoSitePlus	COSMIC	20.673	Gain
TK_Src_SrcA_SRC_Y	Q13905	RAPGEF1	P12931	SRC	Y155	S148N	148	Missense	distal	-7	no	21.231	21.199	EPSD	COSMIC	20.673	Down-regulation
TK_Src_SrcA_SRC_Y	Q13905	RAPGEF1	P12931	SRC	Y341	R347H	347	Missense	distal	6	no	20.680	20.708	EPSD	COSMIC	20.673	Up-regulation
TK_Src_SrcA_SRC_Y	Q13905	RAPGEF1	P12931	SRC	Y390	H385Y	385	Missense	distal	-5	no	22.528	21.863	EPSD	COSMIC	20.673	Down-regulation
TK_Src_SrcA_SRC_Y	Q13905	RAPGEF1	P12931	SRC	Y390	L397F	397	Missense	distal	7	no	22.528	22.542	EPSD	COSMIC	20.673	Up-regulation
TK_Src_SrcA_SRC_Y	Q13905	RAPGEF1	P12931	SRC	Y390	D396Y	396	Missense	distal	6	no	22.528	22.582	EPSD	COSMIC	20.673	Up-regulation
TK_Src_SrcA_SRC_Y	Q13905	RAPGEF1	P12931	SRC	Y390	Y386C	386	Missense	distal	-4	no	22.528	21.245	EPSD	COSMIC	20.673	Down-regulation
TK_Src_SrcA_SRC_Y	Q13905	RAPGEF1	P12931	SRC	Y390	D387N	387	Missense	distal	-3	no	22.528	22.020	EPSD	COSMIC	20.673	Down-regulation
TK_Src_SrcA_SRC_Y	Q13905	RAPGEF1	P12931	SRC	Y579	Y579C	579	Missense	central	0	yes	22.234	0.000	EPSD	COSMIC	20.673	Loss
TK_Src_SrcA_SRC_Y	Q13905	RAPGEF1	P12931	SRC	Y579	L585R	585	Missense	distal	6	no	22.234	22.197	EPSD	COSMIC	20.673	Down-regulation
TK_Src_SrcA_SRC_Y	Q13905	RAPGEF1	P12931	SRC	Y579	E576K	576	Missense	distal	-3	no	22.234	20.523	EPSD	COSMIC	20.673	Loss
TK_Src_SrcA_SRC_Y	Q13905	RAPGEF1	P12931	SRC	Y579	T572M	572	Missense	distal	-7	no	22.234	21.597	EPSD	COSMIC	20.673	Down-regulation
TK_Src_SrcA_SRC_Y	Q13905	RAPGEF1	P12931	SRC	Y579	K584N	584	Missense	distal	5	no	22.234	22.152	EPSD	COSMIC	20.673	Down-regulation
TK_Src_SrcA_SRC_Y	Q13905	RAPGEF1	P12931	SRC	Y579	H577L	577	Missense	proximal	-2	no	22.234	21.369	EPSD	COSMIC	20.673	Down-regulation
TK_Src_SrcA_SRC_Y	Q13905	RAPGEF1	P12931	SRC	Y579	Q580K	580	Missense	proximal	1	no	22.234	20.825	EPSD	COSMIC	20.673	Down-regulation
TK_Src_SrcA_SRC_Y	Q13905	RAPGEF1	P12931	SRC	Y579	I578M	578	Missense	proximal	-1	no	22.234	21.003	EPSD	COSMIC	20.673	Down-regulation
TK_Src_SrcA_SRC_Y	Q13905	RAPGEF1	P12931	SRC	Y590	M587T	587	Missense	distal	-3	no	20.139	21.368	EPSD	COSMIC	20.673	Gain
TK_Src_SrcA_SRC_Y	P63010	AP2B1	P12931	SRC	Y136	L130I	130	Missense	distal	-6	no	20.851	20.897	EPSD	COSMIC	20.673	Up-regulation
TK_Src_SrcA_SRC_Y	P63010	AP2B1	P12931	SRC	Y136	V143I	143	Missense	distal	7	no	20.851	20.825	EPSD	COSMIC	20.673	Down-regulation
TK_Src_SrcA_SRC_Y	P63010	AP2B1	P12931	SRC	Y136	A142V	142	Missense	distal	6	no	20.851	20.860	EPSD	COSMIC	20.673	Up-regulation
TK_Src_SrcA_SRC_Y	P63010	AP2B1	P12931	SRC	Y136	C129G	129	Missense	distal	-7	no	20.851	21.371	EPSD	COSMIC	20.673	Up-regulation
TK_Src_SrcA_SRC_Y	P63010	AP2B1	P12931	SRC	Y276	L270V	270	Missense	distal	-6	no	20.937	20.756	EPSD	COSMIC	20.673	Down-regulation
TK_Src_SrcA_SRC_Y	P63010	AP2B1	P12931	SRC	Y277	L270V	270	Missense	distal	-7	no	21.866	21.830	EPSD	COSMIC	20.673	Down-regulation
TK_Src_SrcA_SRC_Y	P63010	AP2B1	P12931	SRC	Y333	P331L	331	Missense	proximal	-2	no	21.042	19.511	EPSD	COSMIC	20.673	Loss
TK_Src_SrcA_SRC_Y	P63010	AP2B1	P12931	SRC	Y333	P331S	331	Missense	proximal	-2	no	21.042	20.256	EPSD	COSMIC	20.673	Loss
TK_Src_SrcA_SRC_Y	P63000	RAC1	P12931	SRC	Y64	L67I	67	Missense	distal	3	no	21.521	21.433	PhosphoSitePlus	COSMIC	20.673	Down-regulation
TK_Src_SrcA_SRC_Y	P63000	RAC1	P12931	SRC	Y64	G60R	60	Missense	distal	-4	no	21.521	21.503	PhosphoSitePlus	COSMIC	20.673	Down-regulation
TK_Src_SrcA_SRC_Y	P63000	RAC1	P12931	SRC	Y64	D65Y	65	Missense	proximal	1	no	21.521	21.122	PhosphoSitePlus	COSMIC	20.673	Down-regulation
TK_Src_SrcA_SRC_Y	P63000	RAC1	P12931	SRC	Y64	Q61K	61	Missense	distal	-3	no	21.521	20.689	PhosphoSitePlus	COSMIC	20.673	Down-regulation
TK_Src_SrcA_SRC_Y	P63000	RAC1	P12931	SRC	Y64	P69L	69	Missense	distal	5	no	21.521	21.535	PhosphoSitePlus	COSMIC	20.673	Up-regulation
TK_Src_SrcA_SRC_Y	P63000	RAC1	P12931	SRC	Y64	D65N	65	Missense	proximal	1	no	21.521	20.129	PhosphoSitePlus	COSMIC	20.673	Loss
TK_Src_SrcA_SRC_Y	P63000	RAC1	P12931	SRC	Y64	D57E	57	Missense	distal	-7	no	21.521	21.549	PhosphoSitePlus	COSMIC	20.673	Up-regulation
TK_Src_SrcA_SRC_Y	P63000	RAC1	P12931	SRC	Y64	A59T	59	Missense	distal	-5	no	21.521	21.310	PhosphoSitePlus	COSMIC;CCLE	20.673	Down-regulation
TK_Src_SrcA_SRC_Y	P63000	RAC1	P12931	SRC	Y64	D63G	63	Missense	proximal	-1	no	21.521	20.963	PhosphoSitePlus	COSMIC	20.673	Down-regulation
TK_Src_SrcA_SRC_Y	P63000	RAC1	P12931	SRC	Y64	D63V	63	Missense	proximal	-1	no	21.521	22.954	PhosphoSitePlus	COSMIC	20.673	Up-regulation
TK_Src_SrcA_SRC_Y	P04049	RAF1	P12931	SRC	Y340	R333C	333	Missense	distal	-7	no	24.009	22.867	PhosphoSitePlus;EPSD	COSMIC	20.673	Down-regulation
TK_Src_SrcA_SRC_Y	P04049	RAF1	P12931	SRC	Y340	Q335H	335	Missense	distal	-5	no	24.009	24.378	PhosphoSitePlus;EPSD	COSMIC;GDSC;CCLE	20.673	Up-regulation
TK_Src_SrcA_SRC_Y	P04049	RAF1	P12931	SRC	Y341	Q335H	335	Missense	distal	-6	no	22.588	22.453	EPSD;PhosphoSitePlus	COSMIC;GDSC;CCLE	20.673	Down-regulation
TK_Src_SrcA_SRC_Y	P51809	VAMP7	P12931	SRC	Y45	K42N	42	Missense	distal	-3	no	20.005	21.254	PhosphoSitePlus	COSMIC	20.673	Gain
TK_Src_SrcA_SRC_Y	Q12913	PTPRJ	P12931	SRC	Y346	T344P	344	Missense	proximal	-2	no	19.767	20.790	EPSD	COSMIC	20.673	Gain
TK_Src_SrcA_SRC_Y	Q12913	PTPRJ	P12931	SRC	Y1094	Y1099C	1099	Missense	distal	5	no	21.844	21.888	EPSD	COSMIC	20.673	Up-regulation
TK_Src_SrcA_SRC_Y	Q12913	PTPRJ	P12931	SRC	Y1094	Q1087H	1087	Missense	distal	-7	no	21.844	21.773	EPSD	COSMIC	20.673	Down-regulation
TK_Src_SrcA_SRC_Y	Q12913	PTPRJ	P12931	SRC	Y1311	S1305L	1305	Missense	distal	-6	no	20.784	20.715	EPSD;PhosphoSitePlus	COSMIC;GDSC;CCLE	20.673	Down-regulation
TK_Src_SrcA_SRC_Y	Q12913	PTPRJ	P12931	SRC	Y1311	A1316T	1316	Missense	distal	5	no	20.784	20.999	EPSD;PhosphoSitePlus	COSMIC	20.673	Up-regulation
TK_Src_SrcA_SRC_Y	Q12913	PTPRJ	P12931	SRC	Y1311	L1309F	1309	Missense	proximal	-2	no	20.784	20.548	EPSD;PhosphoSitePlus	COSMIC	20.673	Loss
TK_Src_SrcA_SRC_Y	O15350	TP73	P12931	SRC	Y28	D30A	30	Missense	proximal	2	no	21.706	21.815	PhosphoSitePlus	COSMIC	20.673	Up-regulation
TK_Src_SrcA_SRC_Y	O15350	TP73	P12931	SRC	Y28	S26L	26	Missense	proximal	-2	no	21.706	20.962	PhosphoSitePlus	COSMIC	20.673	Down-regulation
TK_Src_SrcA_SRC_Y	Q96KG7	MEGF10	P12931	SRC	Y1016	S1014Y	1014	Missense	proximal	-2	no	22.190	21.642	EPSD	COSMIC;GDSC;CCLE	20.673	Down-regulation
TK_Src_SrcA_SRC_Y	Q96KG7	MEGF10	P12931	SRC	Y1030	Y1030C	1030	Missense	central	0	yes	21.659	0.000	PhosphoSitePlus	COSMIC	20.673	Loss
TK_Src_SrcA_SRC_Y	Q96KG7	MEGF10	P12931	SRC	Y1061	P1054T	1054	Missense	distal	-7	no	22.793	23.010	EPSD	COSMIC	20.673	Up-regulation
TK_Src_SrcA_SRC_Y	Q96KG7	MEGF10	P12931	SRC	Y1061	T1068I	1068	Missense	distal	7	no	22.793	22.863	EPSD	COSMIC	20.673	Up-regulation
TK_Src_SrcA_SRC_Y	Q96KG7	MEGF10	P12931	SRC	Y1061	T1068N	1068	Missense	distal	7	no	22.793	22.790	EPSD	COSMIC;GDSC;CCLE	20.673	Down-regulation
TK_Src_SrcA_SRC_Y	Q96KG7	MEGF10	P12931	SRC	Y1075	T1068I	1068	Missense	distal	-7	no	24.403	24.051	EPSD	COSMIC	20.673	Down-regulation
TK_Src_SrcA_SRC_Y	Q96KG7	MEGF10	P12931	SRC	Y1075	T1068N	1068	Missense	distal	-7	no	24.403	24.275	EPSD	COSMIC;GDSC;CCLE	20.673	Down-regulation
TK_Src_SrcA_SRC_Y	Q96KG7	MEGF10	P12931	SRC	Y1075	P1079L	1079	Missense	distal	4	no	24.403	24.432	EPSD	COSMIC;GDSC;CCLE	20.673	Up-regulation
TK_Src_SrcA_SRC_Y	Q96KG7	MEGF10	P12931	SRC	Y1075	S1082G	1082	Missense	distal	7	no	24.403	24.434	EPSD	COSMIC	20.673	Up-regulation
TK_Src_SrcA_SRC_Y	P19404	NDUFV2	P12931	SRC	Y193	L196F	196	Missense	distal	3	no	24.443	24.683	PhosphoSitePlus	COSMIC	20.673	Up-regulation
TK_Src_SrcA_SRC_Y	P52789	HK2	P12931	SRC	Y25	V22D	22	Missense	distal	-3	no	19.554	21.479	EPSD	COSMIC	20.673	Gain
TK_Src_SrcA_SRC_Y	P52789	HK2	P12931	SRC	Y112	V105L	105	Missense	distal	-7	no	21.159	21.196	EPSD	COSMIC	20.673	Up-regulation
TK_Src_SrcA_SRC_Y	P52789	HK2	P12931	SRC	Y112	I118V	118	Missense	distal	6	no	21.159	21.153	EPSD	COSMIC	20.673	Down-regulation
TK_Src_SrcA_SRC_Y	P52789	HK2	P12931	SRC	Y417	G414D	414	Missense	distal	-3	no	21.755	22.404	EPSD	COSMIC	20.673	Up-regulation
TK_Src_SrcA_SRC_Y	P52789	HK2	P12931	SRC	Y417	S415P	415	Missense	proximal	-2	no	21.755	22.541	EPSD	COSMIC	20.673	Up-regulation
TK_Src_SrcA_SRC_Y	P52789	HK2	P12931	SRC	Y417	V412A	412	Missense	distal	-5	no	21.755	21.754	EPSD	COSMIC	20.673	Down-regulation
TK_Src_SrcA_SRC_Y	Q13936	CACNA1C	P12931	SRC	Y1142	Y1142C	1142	Missense	central	0	yes	20.948	0.000	EPSD	COSMIC	20.673	Loss
TK_Src_SrcA_SRC_Y	Q13936	CACNA1C	P12931	SRC	Y1142	R1143G	1143	Missense	proximal	1	no	20.948	21.942	EPSD	COSMIC	20.673	Up-regulation
TK_Src_SrcA_SRC_Y	Q13936	CACNA1C	P12931	SRC	Y1142	G1136W	1136	Missense	distal	-6	no	20.948	20.683	EPSD	COSMIC	20.673	Down-regulation
TK_Src_SrcA_SRC_Y	Q13936	CACNA1C	P12931	SRC	Y1920	E1921Q	1921	Missense	proximal	1	no	21.274	20.289	EPSD	COSMIC	20.673	Loss
TK_Src_SrcA_SRC_Y	Q13936	CACNA1C	P12931	SRC	Y1920	S1915F	1915	Missense	distal	-5	no	21.274	20.951	EPSD	COSMIC	20.673	Down-regulation
TK_Src_SrcA_SRC_Y	Q13936	CACNA1C	P12931	SRC	Y1920	Q1916R	1916	Missense	distal	-4	no	21.274	21.653	EPSD	COSMIC	20.673	Up-regulation
TK_Src_SrcA_SRC_Y	Q13936	CACNA1C	P12931	SRC	Y1920	S1915T	1915	Missense	distal	-5	no	21.274	20.965	EPSD	COSMIC	20.673	Down-regulation
TK_Src_SrcA_SRC_Y	Q13936	CACNA1C	P12931	SRC	Y1920	D1917N	1917	Missense	distal	-3	no	21.274	20.766	EPSD	COSMIC	20.673	Down-regulation
TK_Src_SrcA_SRC_Y	P14921	ETS1	P12931	SRC	Y283	D287N	287	Missense	distal	4	no	20.953	20.969	PhosphoSitePlus	COSMIC	20.673	Up-regulation
TK_Src_SrcA_SRC_Y	P14921	ETS1	P12931	SRC	Y283	R279H	279	Missense	distal	-4	no	20.953	20.469	PhosphoSitePlus	COSMIC;CCLE	20.673	Loss
TK_Src_SrcA_SRC_Y	P14921	ETS1	P12931	SRC	Y283	Q278K	278	Missense	distal	-5	no	20.953	20.804	PhosphoSitePlus	COSMIC	20.673	Down-regulation
TK_Src_SrcA_SRC_Y	P14921	ETS1	P12931	SRC	Y283	L277R	277	Missense	distal	-6	no	20.953	20.881	PhosphoSitePlus	COSMIC	20.673	Down-regulation
TK_Src_SrcA_SRC_Y	P14921	ETS1	P12931	SRC	Y283	R279C	279	Missense	distal	-4	no	20.953	19.353	PhosphoSitePlus	COSMIC	20.673	Loss
TK_Src_SrcA_SRC_Y	P14921	ETS1	P12931	SRC	Y291	A294T	294	Missense	distal	3	no	21.512	21.556	EPSD	COSMIC	20.673	Up-regulation
TK_Src_SrcA_SRC_Y	P14921	ETS1	P12931	SRC	Y291	D287N	287	Missense	distal	-4	no	21.512	20.980	EPSD	COSMIC	20.673	Down-regulation
TK_Src_SrcA_SRC_Y	P14921	ETS1	P12931	SRC	Y291	A294S	294	Missense	distal	3	no	21.512	21.468	EPSD	COSMIC	20.673	Down-regulation
TK_Src_SrcA_SRC_Y	P14921	ETS1	P12931	SRC	Y291	L295M	295	Missense	distal	4	no	21.512	21.440	EPSD	COSMIC	20.673	Down-regulation
TK_Src_SrcA_SRC_Y	P23743	DGKA	P12931	SRC	Y623	D621N	621	Missense	proximal	-2	no	23.173	22.893	EPSD	COSMIC	20.673	Down-regulation
TK_Src_SrcA_SRC_Y	P23743	DGKA	P12931	SRC	Y623	A628T	628	Missense	distal	5	no	23.173	23.388	EPSD	COSMIC	20.673	Up-regulation
TK_Src_SrcA_SRC_Y	P23743	DGKA	P12931	SRC	Y623	Y623C	623	Missense	central	0	yes	23.173	0.000	EPSD	COSMIC	20.673	Loss
TK_Src_SrcA_SRC_Y	Q00987	MDM2	P12931	SRC	Y276	D272N	272	Missense	distal	-4	no	25.085	24.553	EPSD	COSMIC	20.673	Down-regulation
TK_Src_SrcA_SRC_Y	Q00987	MDM2	P12931	SRC	Y276	Y276C	276	Missense	central	0	yes	25.085	0.000	EPSD	COSMIC	20.673	Loss
TK_Src_SrcA_SRC_Y	Q00987	MDM2	P12931	SRC	Y276	Y276H	276	Missense	central	0	yes	25.085	0.000	EPSD	COSMIC	20.673	Loss
TK_Src_SrcA_SRC_Y	Q00987	MDM2	P12931	SRC	Y276	A283T	283	Missense	distal	7	no	25.085	25.066	EPSD	COSMIC	20.673	Down-regulation
TK_Src_SrcA_SRC_Y	Q00987	MDM2	P12931	SRC	Y276	Y281H	281	Missense	distal	5	no	25.085	24.801	EPSD	COSMIC	20.673	Down-regulation
TK_Src_SrcA_SRC_Y	Q00987	MDM2	P12931	SRC	Y276	T279P	279	Missense	distal	3	no	25.085	25.736	EPSD	COSMIC	20.673	Up-regulation
TK_Src_SrcA_SRC_Y	Q00987	MDM2	P12931	SRC	Y276	V278D	278	Missense	proximal	2	no	25.085	24.766	EPSD	COSMIC	20.673	Down-regulation
TK_Src_SrcA_SRC_Y	Q00987	MDM2	P12931	SRC	Y276	V278A	278	Missense	proximal	2	no	25.085	24.874	EPSD	COSMIC	20.673	Down-regulation
TK_Src_SrcA_SRC_Y	Q00987	MDM2	P12931	SRC	Y276	E271D	271	Missense	distal	-5	no	25.085	24.985	EPSD	COSMIC	20.673	Down-regulation
TK_Src_SrcA_SRC_Y	Q00987	MDM2	P12931	SRC	Y281	G284W	284	Missense	distal	3	no	22.943	21.562	PhosphoSitePlus;EPSD	COSMIC	20.673	Down-regulation
TK_Src_SrcA_SRC_Y	Q00987	MDM2	P12931	SRC	Y281	Y276C	276	Missense	distal	-5	no	22.943	22.679	PhosphoSitePlus;EPSD	COSMIC	20.673	Down-regulation
TK_Src_SrcA_SRC_Y	Q00987	MDM2	P12931	SRC	Y281	Y276H	276	Missense	distal	-5	no	22.943	23.608	PhosphoSitePlus;EPSD	COSMIC	20.673	Up-regulation
TK_Src_SrcA_SRC_Y	Q00987	MDM2	P12931	SRC	Y281	A283T	283	Missense	proximal	2	no	22.943	23.037	PhosphoSitePlus;EPSD	COSMIC	20.673	Up-regulation
TK_Src_SrcA_SRC_Y	Q00987	MDM2	P12931	SRC	Y281	Y281H	281	Missense	central	0	yes	22.943	0.000	PhosphoSitePlus;EPSD	COSMIC	20.673	Loss
TK_Src_SrcA_SRC_Y	Q00987	MDM2	P12931	SRC	Y281	T279P	279	Missense	proximal	-2	no	22.943	23.967	PhosphoSitePlus;EPSD	COSMIC	20.673	Up-regulation
TK_Src_SrcA_SRC_Y	Q00987	MDM2	P12931	SRC	Y281	V278D	278	Missense	distal	-3	no	22.943	24.868	PhosphoSitePlus;EPSD	COSMIC	20.673	Up-regulation
TK_Src_SrcA_SRC_Y	Q00987	MDM2	P12931	SRC	Y281	E285K	285	Missense	distal	4	no	22.943	22.944	PhosphoSitePlus;EPSD	COSMIC	20.673	Up-regulation
TK_Src_SrcA_SRC_Y	Q00987	MDM2	P12931	SRC	Y281	D287N	287	Missense	distal	6	no	22.943	22.947	PhosphoSitePlus;EPSD	COSMIC	20.673	Up-regulation
TK_Src_SrcA_SRC_Y	Q00987	MDM2	P12931	SRC	Y281	V278A	278	Missense	distal	-3	no	22.943	23.494	PhosphoSitePlus;EPSD	COSMIC	20.673	Up-regulation
TK_Src_SrcA_SRC_Y	Q00987	MDM2	P12931	SRC	Y394	D393E	393	Missense	proximal	-1	no	25.302	26.212	EPSD	COSMIC	20.673	Up-regulation
TK_Src_SrcA_SRC_Y	Q00987	MDM2	P12931	SRC	Y394	D393H	393	Missense	proximal	-1	no	25.302	25.869	EPSD	COSMIC	20.673	Up-regulation
TK_Src_SrcA_SRC_Y	P36544	CHRNA7	P12931	SRC	Y386	A379T	379	Missense	distal	-7	no	21.135	21.555	PhosphoSitePlus;EPSD	COSMIC	20.673	Up-regulation
TK_Src_SrcA_SRC_Y	P36544	CHRNA7	P12931	SRC	Y386	G382R	382	Missense	distal	-4	no	21.135	21.116	PhosphoSitePlus;EPSD	COSMIC;CCLE	20.673	Down-regulation
TK_Src_SrcA_SRC_Y	P36544	CHRNA7	P12931	SRC	Y386	G388C	388	Missense	proximal	2	no	21.135	20.831	PhosphoSitePlus;EPSD	COSMIC	20.673	Down-regulation
TK_Src_SrcA_SRC_Y	P36544	CHRNA7	P12931	SRC	Y386	G391D	391	Missense	distal	5	no	21.135	20.770	PhosphoSitePlus;EPSD	COSMIC	20.673	Down-regulation
TK_Src_SrcA_SRC_Y	P36544	CHRNA7	P12931	SRC	Y386	S380G	380	Missense	distal	-6	no	21.135	20.992	PhosphoSitePlus;EPSD	COSMIC	20.673	Down-regulation
TK_Src_SrcA_SRC_Y	P36544	CHRNA7	P12931	SRC	Y386	G382E	382	Missense	distal	-4	no	21.135	21.568	PhosphoSitePlus;EPSD	COSMIC;CCLE	20.673	Up-regulation
TK_Src_SrcA_SRC_Y	P36544	CHRNA7	P12931	SRC	Y386	R390H	390	Missense	distal	4	no	21.135	21.148	PhosphoSitePlus;EPSD	COSMIC	20.673	Up-regulation
TK_Src_SrcA_SRC_Y	P03372	ESR1	P12931	SRC	Y52	G57C	57	Missense	distal	5	no	20.566	20.818	EPSD	COSMIC	20.673	Gain
TK_Src_SrcA_SRC_Y	P03372	ESR1	P12931	SRC	Y52	A50T	50	Missense	proximal	-2	no	20.566	20.694	EPSD	COSMIC	20.673	Gain
TK_Src_SrcA_SRC_Y	P03372	ESR1	P12931	SRC	Y52	K48N	48	Missense	distal	-4	no	20.566	21.429	EPSD	COSMIC	20.673	Gain
TK_Src_SrcA_SRC_Y	P03372	ESR1	P12931	SRC	Y52	P49S	49	Missense	distal	-3	no	20.566	21.684	EPSD	COSMIC	20.673	Gain
TK_Src_SrcA_SRC_Y	P03372	ESR1	P12931	SRC	Y537	Y537D	537	Missense	central	0	yes	21.208	0.000	PhosphoSitePlus	COSMIC	20.673	Loss
TK_Src_SrcA_SRC_Y	P03372	ESR1	P12931	SRC	Y537	V534E	534	Missense	distal	-3	no	21.208	23.087	PhosphoSitePlus	COSMIC	20.673	Up-regulation
TK_Src_SrcA_SRC_Y	P03372	ESR1	P12931	SRC	Y537	E542G	542	Missense	distal	5	no	21.208	21.365	PhosphoSitePlus	COSMIC	20.673	Up-regulation
TK_Src_SrcA_SRC_Y	P03372	ESR1	P12931	SRC	Y537	C530L	530	Missense	distal	-7	no	21.208	21.866	PhosphoSitePlus	COSMIC	20.673	Up-regulation
TK_Src_SrcA_SRC_Y	P03372	ESR1	P12931	SRC	Y537	L536H	536	Missense	proximal	-1	no	21.208	21.451	PhosphoSitePlus	COSMIC	20.673	Up-regulation
TK_Src_SrcA_SRC_Y	P03372	ESR1	P12931	SRC	Y537	L536P	536	Missense	proximal	-1	no	21.208	21.221	PhosphoSitePlus	COSMIC	20.673	Up-regulation
TK_Src_SrcA_SRC_Y	P03372	ESR1	P12931	SRC	Y537	L536R	536	Missense	proximal	-1	no	21.208	19.555	PhosphoSitePlus	COSMIC	20.673	Loss
TK_Src_SrcA_SRC_Y	P03372	ESR1	P12931	SRC	Y537	L540Q	540	Missense	distal	3	no	21.208	19.931	PhosphoSitePlus	COSMIC	20.673	Loss
TK_Src_SrcA_SRC_Y	P03372	ESR1	P12931	SRC	Y537	N532K	532	Missense	distal	-5	no	21.208	20.944	PhosphoSitePlus	COSMIC	20.673	Down-regulation
TK_Src_SrcA_SRC_Y	P03372	ESR1	P12931	SRC	Y537	P535T	535	Missense	proximal	-2	no	21.208	20.184	PhosphoSitePlus	COSMIC	20.673	Loss
TK_Src_SrcA_SRC_Y	P03372	ESR1	P12931	SRC	Y537	L536Q	536	Missense	proximal	-1	no	21.208	21.387	PhosphoSitePlus	COSMIC	20.673	Up-regulation
TK_Src_SrcA_SRC_Y	P03372	ESR1	P12931	SRC	Y537	V534M	534	Missense	distal	-3	no	21.208	20.725	PhosphoSitePlus	COSMIC	20.673	Down-regulation
TK_Src_SrcA_SRC_Y	P03372	ESR1	P12931	SRC	Y537	K531E	531	Missense	distal	-6	no	21.208	21.220	PhosphoSitePlus	COSMIC	20.673	Up-regulation
TK_Src_SrcA_SRC_Y	P03372	ESR1	P12931	SRC	Y537	P535H	535	Missense	proximal	-2	no	21.208	20.542	PhosphoSitePlus	COSMIC	20.673	Loss
TK_Src_SrcA_SRC_Y	P18827	SDC1	P12931	SRC	Y299	E306Q	306	Missense	distal	7	no	20.945	20.933	EPSD	COSMIC	20.673	Down-regulation
TK_Src_SrcA_SRC_Y	Q9UKW4	VAV3	P12931	SRC	Y141	G143D	143	Missense	proximal	2	no	24.102	24.769	EPSD	COSMIC	20.673	Up-regulation
TK_Src_SrcA_SRC_Y	Q9UKW4	VAV3	P12931	SRC	Y207	S213P	213	Missense	distal	6	no	21.098	21.114	EPSD	COSMIC	20.673	Up-regulation
TK_Src_SrcA_SRC_Y	Q9UKW4	VAV3	P12931	SRC	Y207	E212V	212	Missense	distal	5	no	21.098	21.146	EPSD	COSMIC	20.673	Up-regulation
TK_Src_SrcA_SRC_Y	Q9UKW4	VAV3	P12931	SRC	Y207	E209Q	209	Missense	proximal	2	no	21.098	20.789	EPSD	COSMIC	20.673	Down-regulation
TK_Src_SrcA_SRC_Y	Q9UKW4	VAV3	P12931	SRC	Y207	T208A	208	Missense	proximal	1	no	21.098	21.552	EPSD	COSMIC	20.673	Up-regulation
TK_Src_SrcA_SRC_Y	Q9UKW4	VAV3	P12931	SRC	Y207	E212K	212	Missense	distal	5	no	21.098	21.130	EPSD	COSMIC	20.673	Up-regulation
TK_Src_SrcA_SRC_Y	Q9UKW4	VAV3	P12931	SRC	Y265	N258H	258	Missense	distal	-7	no	23.288	23.272	EPSD	COSMIC	20.673	Down-regulation
TK_Src_SrcA_SRC_Y	Q9UKW4	VAV3	P12931	SRC	Y265	Q266K	266	Missense	proximal	1	no	23.288	21.878	EPSD	COSMIC	20.673	Down-regulation
TK_Src_SrcA_SRC_Y	Q9UKW4	VAV3	P12931	SRC	Y265	V267G	267	Missense	proximal	2	no	23.288	22.301	EPSD	COSMIC	20.673	Down-regulation
TK_Src_SrcA_SRC_Y	Q9UKW4	VAV3	P12931	SRC	Y706	S703L	703	Missense	distal	-3	no	21.623	19.355	EPSD	COSMIC	20.673	Loss
TK_Src_SrcA_SRC_Y	Q9UKW4	VAV3	P12931	SRC	Y706	K701Q	701	Missense	distal	-5	no	21.623	21.772	EPSD	COSMIC	20.673	Up-regulation
TK_Src_SrcA_SRC_Y	P61586	RHOA	P12931	SRC	Y66	R70K	70	Missense	distal	4	no	20.795	20.810	PhosphoSitePlus;EPSD	COSMIC;GDSC;CCLE	20.673	Up-regulation
TK_Src_SrcA_SRC_Y	P61586	RHOA	P12931	SRC	Y66	T60A	60	Missense	distal	-6	no	20.795	20.758	PhosphoSitePlus;EPSD	COSMIC	20.673	Down-regulation
TK_Src_SrcA_SRC_Y	P61586	RHOA	P12931	SRC	Y66	S73Y	73	Missense	distal	7	no	20.795	20.782	PhosphoSitePlus;EPSD	COSMIC	20.673	Down-regulation
TK_Src_SrcA_SRC_Y	P61586	RHOA	P12931	SRC	Y66	D65Y	65	Missense	proximal	-1	no	20.795	21.957	PhosphoSitePlus;EPSD	COSMIC	20.673	Up-regulation
TK_Src_SrcA_SRC_Y	P61586	RHOA	P12931	SRC	Y66	G62V	62	Missense	distal	-4	no	20.795	19.979	PhosphoSitePlus;EPSD	COSMIC	20.673	Loss
TK_Src_SrcA_SRC_Y	P61586	RHOA	P12931	SRC	Y66	Q63R	63	Missense	distal	-3	no	20.795	20.179	PhosphoSitePlus;EPSD	COSMIC	20.673	Loss
TK_Src_SrcA_SRC_Y	P61586	RHOA	P12931	SRC	Y66	E64K	64	Missense	proximal	-2	no	20.795	19.436	PhosphoSitePlus;EPSD	COSMIC	20.673	Loss
TK_Src_SrcA_SRC_Y	P61586	RHOA	P12931	SRC	Y66	R68L	68	Missense	proximal	2	no	20.795	20.562	PhosphoSitePlus;EPSD	COSMIC	20.673	Loss
TK_Src_SrcA_SRC_Y	P61586	RHOA	P12931	SRC	Y66	R68H	68	Missense	proximal	2	no	20.795	20.643	PhosphoSitePlus;EPSD	COSMIC	20.673	Loss
TK_Src_SrcA_SRC_Y	P61586	RHOA	P12931	SRC	Y66	L72P	72	Missense	distal	6	no	20.795	20.779	PhosphoSitePlus;EPSD	COSMIC	20.673	Down-regulation
TK_Src_SrcA_SRC_Y	P07949	RET	P12931	SRC	Y687	S690F	690	Missense	distal	3	no	20.253	21.134	EPSD	COSMIC	20.673	Gain
TK_Src_SrcA_SRC_Y	P07949	RET	P12931	SRC	Y687	P684S	684	Missense	distal	-3	no	20.253	21.370	EPSD	COSMIC	20.673	Gain
TK_Src_SrcA_SRC_Y	P07949	RET	P12931	SRC	Y809	A807P	807	Missense	proximal	-2	no	20.746	21.898	EPSD	COSMIC	20.673	Up-regulation
TK_Src_SrcA_SRC_Y	P07949	RET	P12931	SRC	Y809	L816P	816	Missense	distal	7	no	20.746	20.752	EPSD	COSMIC	20.673	Up-regulation
TK_Src_SrcA_SRC_Y	P07949	RET	P12931	SRC	Y809	V804M	804	Missense	distal	-5	no	20.746	20.427	EPSD	COSMIC;GDSC	20.673	Loss
TK_Src_SrcA_SRC_Y	P07949	RET	P12931	SRC	Y809	K808E	808	Missense	proximal	-1	no	20.746	22.654	EPSD	COSMIC	20.673	Up-regulation
TK_Src_SrcA_SRC_Y	P07949	RET	P12931	SRC	Y900	D903N	903	Missense	distal	3	no	22.850	23.925	EPSD	COSMIC	20.673	Up-regulation
TK_Src_SrcA_SRC_Y	P07949	RET	P12931	SRC	Y900	V899I	899	Missense	proximal	-1	no	22.850	22.475	EPSD	COSMIC	20.673	Down-regulation
TK_Src_SrcA_SRC_Y	P07949	RET	P12931	SRC	Y900	S904P	904	Missense	distal	4	no	22.850	22.828	EPSD	COSMIC	20.673	Down-regulation
TK_Src_SrcA_SRC_Y	P07949	RET	P12931	SRC	Y900	V906M	906	Missense	distal	6	no	22.850	22.878	EPSD	COSMIC	20.673	Up-regulation
TK_Src_SrcA_SRC_Y	P07949	RET	P12931	SRC	Y900	R897Q	897	Missense	distal	-3	no	22.850	23.466	EPSD	COSMIC	20.673	Up-regulation
TK_Src_SrcA_SRC_Y	P07949	RET	P12931	SRC	Y900	E902K	902	Missense	proximal	2	no	22.850	21.680	EPSD	COSMIC	20.673	Down-regulation
TK_Src_SrcA_SRC_Y	P07949	RET	P12931	SRC	Y900	R897P	897	Missense	distal	-3	no	22.850	22.806	EPSD	COSMIC	20.673	Down-regulation
TK_Src_SrcA_SRC_Y	P07949	RET	P12931	SRC	Y900	Y905D	905	Missense	distal	5	no	22.850	22.277	EPSD	COSMIC	20.673	Down-regulation
TK_Src_SrcA_SRC_Y	P07949	RET	P12931	SRC	Y900	L895S	895	Missense	distal	-5	no	22.850	23.108	EPSD	COSMIC	20.673	Up-regulation
TK_Src_SrcA_SRC_Y	P07949	RET	P12931	SRC	Y900	S904F	904	Missense	distal	4	no	22.850	22.839	EPSD	COSMIC	20.673	Down-regulation
TK_Src_SrcA_SRC_Y	P07949	RET	P12931	SRC	Y900	S904L	904	Missense	distal	4	no	22.850	22.857	EPSD	COSMIC	20.673	Up-regulation
TK_Src_SrcA_SRC_Y	P07949	RET	P12931	SRC	Y900	L895W	895	Missense	distal	-5	no	22.850	22.359	EPSD	COSMIC	20.673	Down-regulation
TK_Src_SrcA_SRC_Y	P07949	RET	P12931	SRC	Y905	D903N	903	Missense	proximal	-2	no	24.148	23.868	PhosphoSitePlus	COSMIC	20.673	Down-regulation
TK_Src_SrcA_SRC_Y	P07949	RET	P12931	SRC	Y905	V899I	899	Missense	distal	-6	no	24.148	24.375	PhosphoSitePlus	COSMIC	20.673	Up-regulation
TK_Src_SrcA_SRC_Y	P07949	RET	P12931	SRC	Y905	S904P	904	Missense	proximal	-1	no	24.148	24.499	PhosphoSitePlus	COSMIC	20.673	Up-regulation
TK_Src_SrcA_SRC_Y	P07949	RET	P12931	SRC	Y905	G911D	911	Missense	distal	6	no	24.148	24.107	PhosphoSitePlus	COSMIC	20.673	Down-regulation
TK_Src_SrcA_SRC_Y	P07949	RET	P12931	SRC	Y905	V906M	906	Missense	proximal	1	no	24.148	23.525	PhosphoSitePlus	COSMIC	20.673	Down-regulation
TK_Src_SrcA_SRC_Y	P07949	RET	P12931	SRC	Y905	E902K	902	Missense	distal	-3	no	24.148	22.436	PhosphoSitePlus	COSMIC	20.673	Down-regulation
TK_Src_SrcA_SRC_Y	P07949	RET	P12931	SRC	Y905	Y905D	905	Missense	central	0	yes	24.148	0.000	PhosphoSitePlus	COSMIC	20.673	Loss
TK_Src_SrcA_SRC_Y	P07949	RET	P12931	SRC	Y905	S904F	904	Missense	proximal	-1	no	24.148	23.626	PhosphoSitePlus	COSMIC	20.673	Down-regulation
TK_Src_SrcA_SRC_Y	P07949	RET	P12931	SRC	Y905	S904L	904	Missense	proximal	-1	no	24.148	24.485	PhosphoSitePlus	COSMIC	20.673	Up-regulation
TK_Src_SrcA_SRC_Y	P07949	RET	P12931	SRC	Y905	R908K	908	Missense	distal	3	no	24.148	23.817	PhosphoSitePlus	COSMIC	20.673	Down-regulation
TK_Src_SrcA_SRC_Y	P07949	RET	P12931	SRC	Y928	F924S	924	Missense	distal	-4	no	19.789	20.707	EPSD	COSMIC	20.673	Gain
TK_Src_SrcA_SRC_Y	P07949	RET	P12931	SRC	Y1029	S1026F	1026	Missense	distal	-3	no	22.382	19.788	EPSD	COSMIC	20.673	Loss
TK_Src_SrcA_SRC_Y	P07949	RET	P12931	SRC	Y1029	T1022A	1022	Missense	distal	-7	no	22.382	21.962	EPSD	COSMIC	20.673	Down-regulation
TK_Src_SrcA_SRC_Y	P07949	RET	P12931	SRC	Y1029	E1036Q	1036	Missense	distal	7	no	22.382	22.370	EPSD	COSMIC	20.673	Down-regulation
TK_Src_SrcA_SRC_Y	P07949	RET	P12931	SRC	Y1029	D1031Y	1031	Missense	proximal	2	no	22.382	22.402	EPSD	COSMIC	20.673	Up-regulation
TK_Src_SrcA_SRC_Y	P07949	RET	P12931	SRC	Y1029	S1024F	1024	Missense	distal	-5	no	22.382	22.059	EPSD	COSMIC	20.673	Down-regulation
TK_Src_SrcA_SRC_Y	P07949	RET	P12931	SRC	Y1062	T1055A	1055	Missense	distal	-7	no	21.549	21.129	EPSD	COSMIC	20.673	Down-regulation
TK_Src_SrcA_SRC_Y	P07949	RET	P12931	SRC	Y1062	K1060R	1060	Missense	proximal	-2	no	21.549	20.973	EPSD	COSMIC	20.673	Down-regulation
TK_Src_SrcA_SRC_Y	P07949	RET	P12931	SRC	Y1062	E1058K	1058	Missense	distal	-4	no	21.549	20.379	EPSD	COSMIC	20.673	Loss
TK_Src_SrcA_SRC_Y	P07949	RET	P12931	SRC	Y1062	G1063C	1063	Missense	proximal	1	no	21.549	19.252	EPSD	COSMIC	20.673	Loss
TK_Src_SrcA_SRC_Y	P07949	RET	P12931	SRC	Y1062	N1068S	1068	Missense	distal	6	no	21.549	21.566	EPSD	COSMIC	20.673	Up-regulation
TK_Src_SrcA_SRC_Y	P07949	RET	P12931	SRC	Y1062	M1064L	1064	Missense	proximal	2	no	21.549	20.892	EPSD	COSMIC	20.673	Down-regulation
TK_Src_SrcA_SRC_Y	P07949	RET	P12931	SRC	Y1062	P1067L	1067	Missense	distal	5	no	21.549	21.563	EPSD	COSMIC	20.673	Up-regulation
TK_Src_SrcA_SRC_Y	P07949	RET	P12931	SRC	Y1062	G1063D	1063	Missense	proximal	1	no	21.549	21.927	EPSD	COSMIC	20.673	Up-regulation
TK_Src_SrcA_SRC_Y	P07949	RET	P12931	SRC	Y1096	S1094R	1094	Missense	proximal	-2	no	22.266	21.521	EPSD	COSMIC	20.673	Down-regulation
TK_Src_SrcA_SRC_Y	P07949	RET	P12931	SRC	Y1096	V1095L	1095	Missense	proximal	-1	no	22.266	21.156	EPSD	COSMIC	20.673	Down-regulation
TK_Src_SrcA_SRC_Y	P07949	RET	P12931	SRC	Y1096	W1099Y	1099	Missense	distal	3	no	22.266	23.650	EPSD	COSMIC	20.673	Up-regulation
TK_Src_SrcA_SRC_Y	P07949	RET	P12931	SRC	Y1096	S1094G	1094	Missense	proximal	-2	no	22.266	22.879	EPSD	COSMIC	20.673	Up-regulation
TK_Src_SrcA_SRC_Y	Q92529	SHC3	P12931	SRC	Y406	S402P	402	Missense	distal	-4	no	25.471	25.418	EPSD	COSMIC	20.673	Down-regulation
TK_Src_SrcA_SRC_Y	Q92529	SHC3	P12931	SRC	Y424	P422T	422	Missense	proximal	-2	no	23.493	22.469	EPSD	COSMIC;GDSC;CCLE	20.673	Down-regulation
TK_Src_SrcA_SRC_Y	P23528	CFL1	P12931	SRC	Y68	A69T	69	Missense	proximal	1	no	22.250	21.795	PhosphoSitePlus	COSMIC	20.673	Down-regulation
TK_Src_SrcA_SRC_Y	P23528	CFL1	P12931	SRC	Y85	K78Q	78	Missense	distal	-7	no	20.579	20.689	EPSD	COSMIC	20.673	Gain
TK_Src_SrcA_SRC_Y	P50402	EMD	P12931	SRC	Y74	R68S	68	Missense	distal	-6	no	24.147	24.288	PhosphoSitePlus;EPSD	COSMIC	20.673	Up-regulation
TK_Src_SrcA_SRC_Y	P50402	EMD	P12931	SRC	Y94	D93E	93	Missense	proximal	-1	no	23.020	23.930	EPSD	COSMIC	20.673	Up-regulation
TK_Src_SrcA_SRC_Y	P50402	EMD	P12931	SRC	Y95	D93E	93	Missense	proximal	-2	no	25.691	25.978	EPSD;PhosphoSitePlus	COSMIC	20.673	Up-regulation
TK_Src_SrcA_SRC_Y	P50402	EMD	P12931	SRC	Y99	R103S	103	Missense	distal	4	no	21.540	21.566	EPSD	COSMIC	20.673	Up-regulation
TK_Src_SrcA_SRC_Y	P50402	EMD	P12931	SRC	Y99	D93E	93	Missense	distal	-6	no	21.540	21.463	EPSD	COSMIC	20.673	Down-regulation
TK_Src_SrcA_SRC_Y	P50402	EMD	P12931	SRC	Y105	R103S	103	Missense	proximal	-2	no	20.400	21.146	EPSD	COSMIC	20.673	Gain
TK_Src_SrcA_SRC_Y	P50402	EMD	P12931	SRC	Y161	H166Y	166	Missense	distal	5	no	23.589	23.873	EPSD	COSMIC	20.673	Up-regulation
TK_Src_SrcA_SRC_Y	P50402	EMD	P12931	SRC	Y181	S180Y	180	Missense	proximal	-1	no	20.335	21.511	EPSD	COSMIC	20.673	Gain
TK_Src_SrcA_SRC_Y	P05023	ATP1A1	P12931	SRC	Y10	K9E	9	Missense	proximal	-1	no	21.659	23.568	EPSD	COSMIC	20.673	Up-regulation
TK_Src_SrcA_SRC_Y	P05023	ATP1A1	P12931	SRC	Y10	R7C	7	Missense	distal	-3	no	21.659	20.011	EPSD	COSMIC;GDSC	20.673	Loss
TK_Src_SrcA_SRC_Y	P05023	ATP1A1	P12931	SRC	Y902	G903E	903	Missense	proximal	1	no	20.791	21.775	EPSD	COSMIC	20.673	Up-regulation
TK_Src_SrcA_SRC_Y	P37173	TGFBR2	P12931	SRC	Y259	K262N	262	Missense	distal	3	no	19.690	22.008	EPSD	COSMIC	20.673	Gain
TK_Src_SrcA_SRC_Y	P37173	TGFBR2	P12931	SRC	Y284	K277N	277	Missense	distal	-7	no	20.631	20.685	PhosphoSitePlus	COSMIC	20.673	Gain
TK_Src_SrcA_SRC_Y	P37173	TGFBR2	P12931	SRC	Y284	W287R	287	Missense	distal	3	no	20.631	20.728	PhosphoSitePlus	COSMIC	20.673	Gain
TK_Src_SrcA_SRC_Y	P37173	TGFBR2	P12931	SRC	Y284	P280S	280	Missense	distal	-4	no	20.631	20.684	PhosphoSitePlus	COSMIC	20.673	Gain
TK_Src_SrcA_SRC_Y	P37173	TGFBR2	P12931	SRC	Y284	K277E	277	Missense	distal	-7	no	20.631	20.794	PhosphoSitePlus	COSMIC	20.673	Gain
TK_Src_SrcA_SRC_Y	P37173	TGFBR2	P12931	SRC	Y284	K277R	277	Missense	distal	-7	no	20.631	20.965	PhosphoSitePlus	COSMIC	20.673	Gain
TK_Src_SrcA_SRC_Y	P37173	TGFBR2	P12931	SRC	Y448	A451V	451	Missense	distal	3	no	22.187	22.757	EPSD	COSMIC	20.673	Up-regulation
TK_Src_SrcA_SRC_Y	P37173	TGFBR2	P12931	SRC	Y448	S441P	441	Missense	distal	-7	no	22.187	22.066	EPSD	COSMIC;CCLE	20.673	Down-regulation
TK_Src_SrcA_SRC_Y	P37173	TGFBR2	P12931	SRC	Y448	D446N	446	Missense	proximal	-2	no	22.187	21.907	EPSD	COSMIC;CCLE	20.673	Down-regulation
TK_Src_SrcA_SRC_Y	P37173	TGFBR2	P12931	SRC	Y448	S441F	441	Missense	distal	-7	no	22.187	21.854	EPSD	COSMIC	20.673	Down-regulation
TK_Src_SrcA_SRC_Y	P37173	TGFBR2	P12931	SRC	Y448	V447A	447	Missense	proximal	-1	no	22.187	20.850	EPSD	COSMIC	20.673	Down-regulation
TK_Src_SrcA_SRC_Y	P37173	TGFBR2	P12931	SRC	Y448	F442L	442	Missense	distal	-6	no	22.187	22.254	EPSD	COSMIC	20.673	Up-regulation
TK_Src_SrcA_SRC_Y	P37173	TGFBR2	P12931	SRC	Y448	W455S	455	Missense	distal	7	no	22.187	22.052	EPSD	COSMIC	20.673	Down-regulation
TK_Src_SrcA_SRC_Y	P37173	TGFBR2	P12931	SRC	Y448	L454P	454	Missense	distal	6	no	22.187	22.171	EPSD	COSMIC;CCLE	20.673	Down-regulation
TK_Src_SrcA_SRC_Y	P37173	TGFBR2	P12931	SRC	Y448	L452P	452	Missense	distal	4	no	22.187	22.158	EPSD	COSMIC;CCLE	20.673	Down-regulation
TK_Src_SrcA_SRC_Y	P37173	TGFBR2	P12931	SRC	Y448	F442Y	442	Missense	distal	-6	no	22.187	22.320	EPSD	COSMIC	20.673	Up-regulation
TK_Src_SrcA_SRC_Y	P37173	TGFBR2	P12931	SRC	Y448	Y448C	448	Missense	central	0	yes	22.187	0.000	EPSD	COSMIC	20.673	Loss
TK_Src_SrcA_SRC_Y	P37173	TGFBR2	P12931	SRC	Y448	S449Y	449	Missense	proximal	1	no	22.187	22.281	EPSD	COSMIC	20.673	Up-regulation
TK_Src_SrcA_SRC_Y	P37173	TGFBR2	P12931	SRC	Y448	L452M	452	Missense	distal	4	no	22.187	22.115	EPSD	COSMIC	20.673	Down-regulation
TK_Src_SrcA_SRC_Y	P37173	TGFBR2	P12931	SRC	Y448	D446Y	446	Missense	proximal	-2	no	22.187	20.737	EPSD	COSMIC	20.673	Down-regulation
TK_Src_SrcA_SRC_Y	P37173	TGFBR2	P12931	SRC	Y448	D446G	446	Missense	proximal	-2	no	22.187	21.897	EPSD	COSMIC	20.673	Down-regulation
TK_Src_SrcA_SRC_Y	P37173	TGFBR2	P12931	SRC	Y448	D446V	446	Missense	proximal	-2	no	22.187	20.621	EPSD	COSMIC	20.673	Loss
TK_Src_SrcA_SRC_Y	P37173	TGFBR2	P12931	SRC	Y448	V453M	453	Missense	distal	5	no	22.187	22.481	EPSD	COSMIC	20.673	Up-regulation
TK_Src_SrcA_SRC_Y	P37173	TGFBR2	P12931	SRC	Y448	L452R	452	Missense	distal	4	no	22.187	22.154	EPSD	COSMIC	20.673	Down-regulation
TK_Src_SrcA_SRC_Y	P37173	TGFBR2	P12931	SRC	Y448	F442S	442	Missense	distal	-6	no	22.187	22.323	EPSD	COSMIC	20.673	Up-regulation
TK_Src_SrcA_SRC_Y	P37173	TGFBR2	P12931	SRC	Y470	Y470D	470	Missense	central	0	yes	22.617	0.000	EPSD	COSMIC	20.673	Loss
TK_Src_SrcA_SRC_Y	P37173	TGFBR2	P12931	SRC	Y470	G465E	465	Missense	distal	-5	no	22.617	22.869	EPSD	COSMIC	20.673	Up-regulation
TK_Src_SrcA_SRC_Y	P37173	TGFBR2	P12931	SRC	Y470	K468Q	468	Missense	proximal	-2	no	22.617	22.786	EPSD	COSMIC	20.673	Up-regulation
TK_Src_SrcA_SRC_Y	P37173	TGFBR2	P12931	SRC	Y470	P472T	472	Missense	proximal	2	no	22.617	22.965	EPSD	COSMIC	20.673	Up-regulation
TK_Src_SrcA_SRC_Y	P37173	TGFBR2	P12931	SRC	Y470	F474Y	474	Missense	distal	4	no	22.617	22.593	EPSD	COSMIC	20.673	Down-regulation
TK_Src_SrcA_SRC_Y	Q9H2X6	HIPK2	P12931	SRC	Y367	P370Q	370	Missense	distal	3	no	22.388	21.014	EPSD	COSMIC	20.673	Down-regulation
TK_Src_SrcA_SRC_Y	P53801	PTTG1IP	P12931	SRC	Y174	P173S	173	Missense	proximal	-1	no	22.321	21.970	PhosphoSitePlus	COSMIC	20.673	Down-regulation
TK_Src_SrcA_SRC_Y	P53801	PTTG1IP	P12931	SRC	Y174	E171Q	171	Missense	distal	-3	no	22.321	21.441	PhosphoSitePlus	COSMIC	20.673	Down-regulation
TK_Src_SrcA_SRC_Y	P53801	PTTG1IP	P12931	SRC	Y174	P173T	173	Missense	proximal	-1	no	22.321	22.064	PhosphoSitePlus	COSMIC	20.673	Down-regulation
TK_Src_SrcA_SRC_Y	P53801	PTTG1IP	P12931	SRC	Y174	P173L	173	Missense	proximal	-1	no	22.321	22.308	PhosphoSitePlus	COSMIC;GDSC;CCLE	20.673	Down-regulation
TK_Src_SrcA_SRC_Y	Q9Y446	PKP3	P12931	SRC	Y390	R386C	386	Missense	distal	-4	no	21.488	19.889	EPSD	COSMIC	20.673	Loss
TK_Src_SrcA_SRC_Y	Q9Y446	PKP3	P12931	SRC	Y390	R386H	386	Missense	distal	-4	no	21.488	21.005	EPSD	COSMIC;GDSC	20.673	Down-regulation
TK_Src_SrcA_SRC_Y	P31040	SDHA	P12931	SRC	Y169	Q176H	176	Missense	distal	7	no	23.239	23.268	EPSD	COSMIC	20.673	Up-regulation
TK_Src_SrcA_SRC_Y	P31040	SDHA	P12931	SRC	Y169	R171C	171	Missense	proximal	2	no	23.239	22.639	EPSD	COSMIC	20.673	Down-regulation
TK_Src_SrcA_SRC_Y	P31040	SDHA	P12931	SRC	Y169	A172V	172	Missense	distal	3	no	23.239	23.809	EPSD	COSMIC	20.673	Up-regulation
TK_Src_SrcA_SRC_Y	P31040	SDHA	P12931	SRC	Y169	A172P	172	Missense	distal	3	no	23.239	23.934	EPSD	COSMIC	20.673	Up-regulation
TK_Src_SrcA_SRC_Y	P31040	SDHA	P12931	SRC	Y169	E164Q	164	Missense	distal	-5	no	23.239	22.812	EPSD	COSMIC	20.673	Down-regulation
TK_Src_SrcA_SRC_Y	P31040	SDHA	P12931	SRC	Y169	G166V	166	Missense	distal	-3	no	23.239	21.963	EPSD	COSMIC	20.673	Down-regulation
TK_Src_SrcA_SRC_Y	P31040	SDHA	P12931	SRC	Y169	Y169C	169	Missense	central	0	yes	23.239	0.000	EPSD	COSMIC	20.673	Loss
TK_Src_SrcA_SRC_Y	P31040	SDHA	P12931	SRC	Y169	Q170L	170	Missense	proximal	1	no	23.239	21.580	EPSD	COSMIC	20.673	Down-regulation
TK_Src_SrcA_SRC_Y	P31040	SDHA	P12931	SRC	Y604	Y606H	606	Missense	proximal	2	no	21.211	20.668	EPSD	COSMIC	20.673	Loss
TK_Src_SrcA_SRC_Y	P31040	SDHA	P12931	SRC	Y606	Y606H	606	Missense	central	0	yes	20.944	0.000	EPSD	COSMIC	20.673	Loss
TK_Src_SrcA_SRC_Y	O14746	TERT	P12931	SRC	Y949	A950D	950	Missense	proximal	1	no	21.333	22.025	EPSD	COSMIC	20.673	Up-regulation
TK_Src_SrcA_SRC_Y	O14746	TERT	P12931	SRC	Y949	S953F	953	Missense	distal	4	no	21.333	21.322	EPSD	COSMIC	20.673	Down-regulation
TK_Src_SrcA_SRC_Y	O14746	TERT	P12931	SRC	Y949	R951W	951	Missense	proximal	2	no	21.333	21.690	EPSD	COSMIC	20.673	Up-regulation
TK_Src_SrcA_SRC_Y	O43597	SPRY2	P12931	SRC	Y55	G58A	58	Missense	distal	3	no	22.341	22.148	PhosphoSitePlus	COSMIC	20.673	Down-regulation
TK_Src_SrcA_SRC_Y	Q15746	MYLK	P12931	SRC	Y231	D226Y	226	Missense	distal	-5	no	22.717	22.093	EPSD	COSMIC	20.673	Down-regulation
TK_Src_SrcA_SRC_Y	Q15746	MYLK	P12931	SRC	Y231	D226E	226	Missense	distal	-5	no	22.717	22.817	EPSD	COSMIC	20.673	Up-regulation
TK_Src_SrcA_SRC_Y	Q15746	MYLK	P12931	SRC	Y231	Q225H	225	Missense	distal	-6	no	22.717	22.582	EPSD	COSMIC	20.673	Down-regulation
TK_Src_SrcA_SRC_Y	Q15746	MYLK	P12931	SRC	Y231	G238R	238	Missense	distal	7	no	22.717	22.724	EPSD	COSMIC	20.673	Up-regulation
TK_Src_SrcA_SRC_Y	Q15746	MYLK	P12931	SRC	Y846	G847W	847	Missense	proximal	1	no	21.336	20.259	EPSD	COSMIC	20.673	Loss
TK_Src_SrcA_SRC_Y	P37840	SNCA	P12931	SRC	Y125	A124S	124	Missense	proximal	-1	no	23.320	23.209	PhosphoSitePlus	COSMIC	20.673	Down-regulation
TK_Src_SrcA_SRC_Y	P37840	SNCA	P12931	SRC	Y125	E130V	130	Missense	distal	5	no	23.320	23.368	PhosphoSitePlus	COSMIC	20.673	Up-regulation
TK_Src_SrcA_SRC_Y	P37840	SNCA	P12931	SRC	Y125	E130A	130	Missense	distal	5	no	23.320	23.226	PhosphoSitePlus	COSMIC	20.673	Down-regulation
TK_Src_SrcA_SRC_Y	P37840	SNCA	P12931	SRC	Y125	D121Y	121	Missense	distal	-4	no	23.320	22.327	PhosphoSitePlus	COSMIC	20.673	Down-regulation
TK_Src_SrcA_SRC_Y	P37840	SNCA	P12931	SRC	Y125	E123K	123	Missense	proximal	-2	no	23.320	21.961	PhosphoSitePlus	COSMIC	20.673	Down-regulation
TK_Src_SrcA_SRC_Y	P37840	SNCA	P12931	SRC	Y125	D121E	121	Missense	distal	-4	no	23.320	23.094	PhosphoSitePlus	COSMIC	20.673	Down-regulation
TK_Src_SrcA_SRC_Y	P37840	SNCA	P12931	SRC	Y136	D135E	135	Missense	proximal	-1	no	20.221	21.130	EPSD	COSMIC;GDSC;CCLE	20.673	Gain
TK_Src_SrcA_SRC_Y	P57737	CORO7	P12931	SRC	Y615	S612L	612	Missense	distal	-3	no	21.658	19.389	EPSD	COSMIC	20.673	Loss
TK_Src_SrcA_SRC_Y	P57737	CORO7	P12931	SRC	Y615	R620H	620	Missense	distal	5	no	21.658	21.763	EPSD	COSMIC	20.673	Up-regulation
TK_Src_SrcA_SRC_Y	P57737	CORO7	P12931	SRC	Y883	A881D	881	Missense	proximal	-2	no	20.506	21.775	EPSD	COSMIC	20.673	Gain
TK_Src_SrcA_SRC_Y	P57737	CORO7	P12931	SRC	Y883	A881S	881	Missense	proximal	-2	no	20.506	20.872	EPSD	COSMIC	20.673	Gain
TK_Src_SrcA_SRC_Y	Q14289	PTK2B	P12931	SRC	Y418	G419D	419	Missense	proximal	1	no	20.394	20.772	EPSD	COSMIC	20.673	Gain
TK_Src_SrcA_SRC_Y	Q14289	PTK2B	P12931	SRC	Y418	G414E	414	Missense	distal	-4	no	20.394	20.827	EPSD	COSMIC;GDSC	20.673	Gain
TK_Src_SrcA_SRC_Y	Q14289	PTK2B	P12931	SRC	Y440	T445I	445	Missense	distal	5	no	22.476	22.453	EPSD	COSMIC	20.673	Down-regulation
TK_Src_SrcA_SRC_Y	Q14289	PTK2B	P12931	SRC	Y440	H447Q	447	Missense	distal	7	no	22.476	22.447	EPSD	COSMIC	20.673	Down-regulation
TK_Src_SrcA_SRC_Y	Q14289	PTK2B	P12931	SRC	Y440	E438D	438	Missense	proximal	-2	no	22.476	22.189	EPSD	COSMIC	20.673	Down-regulation
TK_Src_SrcA_SRC_Y	Q14289	PTK2B	P12931	SRC	Y440	E438Q	438	Missense	proximal	-2	no	22.476	21.286	EPSD	COSMIC	20.673	Down-regulation
TK_Src_SrcA_SRC_Y	Q14289	PTK2B	P12931	SRC	Y579	T585I	585	Missense	distal	6	no	26.652	26.682	EPSD	COSMIC	20.673	Up-regulation
TK_Src_SrcA_SRC_Y	Q14289	PTK2B	P12931	SRC	Y579	E577K	577	Missense	proximal	-2	no	26.652	25.293	EPSD	COSMIC;GDSC;CCLE	20.673	Down-regulation
TK_Src_SrcA_SRC_Y	Q14289	PTK2B	P12931	SRC	Y580	T585I	585	Missense	distal	5	no	23.910	23.887	EPSD	COSMIC	20.673	Down-regulation
TK_Src_SrcA_SRC_Y	Q14289	PTK2B	P12931	SRC	Y580	E577K	577	Missense	distal	-3	no	23.910	22.199	EPSD	COSMIC;GDSC;CCLE	20.673	Down-regulation
TK_Src_SrcA_SRC_Y	Q14289	PTK2B	P12931	SRC	Y834	P831S	831	Missense	distal	-3	no	20.093	21.211	EPSD	COSMIC	20.673	Gain
TK_Src_SrcA_SRC_Y	Q14289	PTK2B	P12931	SRC	Y849	T842M	842	Missense	distal	-7	no	21.052	20.415	EPSD	COSMIC;GDSC	20.673	Loss
TK_Src_SrcA_SRC_Y	Q14289	PTK2B	P12931	SRC	Y849	P843L	843	Missense	distal	-6	no	21.052	21.033	EPSD	COSMIC	20.673	Down-regulation
TK_Src_SrcA_SRC_Y	Q14289	PTK2B	P12931	SRC	Y849	E846D	846	Missense	distal	-3	no	21.052	21.098	EPSD	COSMIC	20.673	Up-regulation
TK_Src_SrcA_SRC_Y	Q14289	PTK2B	P12931	SRC	Y881	R875Q	875	Missense	distal	-6	no	22.556	22.658	EPSD	COSMIC	20.673	Up-regulation
TK_Src_SrcA_SRC_Y	P18433	PTPRA	P12931	SRC	Y588	S592F	592	Missense	distal	4	no	22.140	22.129	EPSD	COSMIC	20.673	Down-regulation
TK_Src_SrcA_SRC_Y	P18433	PTPRA	P12931	SRC	Y588	Y588C	588	Missense	central	0	yes	22.140	0.000	EPSD	COSMIC	20.673	Loss
TK_Src_SrcA_SRC_Y	P10275	AR	P12931	SRC	Y11	P12A	12	Missense	proximal	1	no	19.014	20.960	EPSD	COSMIC	20.673	Gain
TK_Src_SrcA_SRC_Y	P10275	AR	P12931	SRC	Y269	P276S	276	Missense	distal	7	no	21.045	21.026	EPSD	COSMIC	20.673	Down-regulation
TK_Src_SrcA_SRC_Y	P10275	AR	P12931	SRC	Y269	P271S	271	Missense	proximal	2	no	21.045	21.653	EPSD	COSMIC	20.673	Up-regulation
TK_Src_SrcA_SRC_Y	P10275	AR	P12931	SRC	Y269	L272P	272	Missense	distal	3	no	21.045	21.143	EPSD	COSMIC	20.673	Up-regulation
TK_Src_SrcA_SRC_Y	P10275	AR	P12931	SRC	Y269	L272F	272	Missense	distal	3	no	21.045	21.286	EPSD	COSMIC	20.673	Up-regulation
TK_Src_SrcA_SRC_Y	P10275	AR	P12931	SRC	Y269	R264Q	264	Missense	distal	-5	no	21.045	20.886	EPSD	COSMIC	20.673	Down-regulation
TK_Src_SrcA_SRC_Y	P10275	AR	P12931	SRC	Y269	A270S	270	Missense	proximal	1	no	21.045	21.245	EPSD	COSMIC	20.673	Up-regulation
TK_Src_SrcA_SRC_Y	P10275	AR	P12931	SRC	Y269	M268T	268	Missense	proximal	-1	no	21.045	21.298	EPSD	COSMIC	20.673	Up-regulation
TK_Src_SrcA_SRC_Y	P10275	AR	P12931	SRC	Y269	G274S	274	Missense	distal	5	no	21.045	20.839	EPSD	COSMIC	20.673	Down-regulation
TK_Src_SrcA_SRC_Y	P10275	AR	P12931	SRC	Y309	D305N	305	Missense	distal	-4	no	23.332	22.800	EPSD	COSMIC	20.673	Down-regulation
TK_Src_SrcA_SRC_Y	P10275	AR	P12931	SRC	Y309	S310F	310	Missense	proximal	1	no	23.332	21.455	EPSD	COSMIC	20.673	Down-regulation
TK_Src_SrcA_SRC_Y	P10275	AR	P12931	SRC	Y309	E304K	304	Missense	distal	-5	no	23.332	22.756	EPSD	COSMIC	20.673	Down-regulation
TK_Src_SrcA_SRC_Y	P10275	AR	P12931	SRC	Y309	T306I	306	Missense	distal	-3	no	23.332	21.481	EPSD	COSMIC;GDSC;CCLE	20.673	Down-regulation
TK_Src_SrcA_SRC_Y	P10275	AR	P12931	SRC	Y309	F312L	312	Missense	distal	3	no	23.332	23.092	EPSD	COSMIC	20.673	Down-regulation
TK_Src_SrcA_SRC_Y	P10275	AR	P12931	SRC	Y364	Q360L	360	Missense	distal	-4	no	21.254	20.676	EPSD	COSMIC	20.673	Down-regulation
TK_Src_SrcA_SRC_Y	P10275	AR	P12931	SRC	Y364	Y364N	364	Missense	central	0	yes	21.254	0.000	EPSD	COSMIC	20.673	Loss
TK_Src_SrcA_SRC_Y	P10275	AR	P12931	SRC	Y364	L371M	371	Missense	distal	7	no	21.254	21.307	EPSD	COSMIC	20.673	Up-regulation
TK_Src_SrcA_SRC_Y	P10275	AR	P12931	SRC	Y395	P392S	392	Missense	distal	-3	no	19.941	21.059	EPSD	COSMIC;GDSC	20.673	Gain
TK_Src_SrcA_SRC_Y	P10275	AR	P12931	SRC	Y395	D394Y	394	Missense	proximal	-1	no	19.941	21.104	EPSD	COSMIC	20.673	Gain
TK_Src_SrcA_SRC_Y	P10275	AR	P12931	SRC	Y535	D529G	529	Missense	distal	-6	no	22.172	21.865	PhosphoSitePlus	COSMIC	20.673	Down-regulation
TK_Src_SrcA_SRC_Y	P10275	AR	P12931	SRC	Y535	P534S	534	Missense	proximal	-1	no	22.172	21.821	PhosphoSitePlus	COSMIC	20.673	Down-regulation
TK_Src_SrcA_SRC_Y	P10275	AR	P12931	SRC	Y535	G536E	536	Missense	proximal	1	no	22.172	23.156	PhosphoSitePlus	COSMIC	20.673	Up-regulation
TK_Src_SrcA_SRC_Y	P10275	AR	P12931	SRC	Y535	R539S	539	Missense	distal	4	no	22.172	22.198	PhosphoSitePlus	COSMIC	20.673	Up-regulation
TK_Src_SrcA_SRC_Y	P10275	AR	P12931	SRC	Y535	D537N	537	Missense	proximal	2	no	22.172	22.385	PhosphoSitePlus	COSMIC	20.673	Up-regulation
TK_Src_SrcA_SRC_Y	P10275	AR	P12931	SRC	Y535	R539H	539	Missense	distal	4	no	22.172	22.185	PhosphoSitePlus	COSMIC	20.673	Up-regulation
TK_Src_SrcA_SRC_Y	P10275	AR	P12931	SRC	Y535	R539Q	539	Missense	distal	4	no	22.172	22.194	PhosphoSitePlus	COSMIC	20.673	Up-regulation
TK_Src_SrcA_SRC_Y	P10275	AR	P12931	SRC	Y535	P534T	534	Missense	proximal	-1	no	22.172	21.915	PhosphoSitePlus	COSMIC	20.673	Down-regulation
TK_Src_SrcA_SRC_Y	O14976	GAK	P12931	SRC	Y235	I232V	232	Missense	distal	-3	no	20.430	21.535	EPSD	COSMIC;GDSC;CCLE	20.673	Gain
TK_Src_SrcA_SRC_Y	O14976	GAK	P12931	SRC	Y285	Y285H	285	Missense	central	0	yes	22.876	0.000	EPSD	COSMIC	20.673	Loss
TK_Src_SrcA_SRC_Y	O14976	GAK	P12931	SRC	Y285	T286M	286	Missense	proximal	1	no	22.876	22.123	EPSD	COSMIC	20.673	Down-regulation
TK_Src_SrcA_SRC_Y	O14976	GAK	P12931	SRC	Y285	H289Y	289	Missense	distal	4	no	22.876	22.854	EPSD	COSMIC	20.673	Down-regulation
TK_Src_SrcA_SRC_Y	O14976	GAK	P12931	SRC	Y285	S290F	290	Missense	distal	5	no	22.876	23.125	EPSD	COSMIC	20.673	Up-regulation
TK_Src_SrcA_SRC_Y	O14976	GAK	P12931	SRC	Y338	E333G	333	Missense	distal	-5	no	20.806	20.554	EPSD	COSMIC	20.673	Loss
TK_Src_SrcA_SRC_Y	O14976	GAK	P12931	SRC	Y338	G339W	339	Missense	proximal	1	no	20.806	19.729	EPSD	COSMIC	20.673	Loss
TK_Src_SrcA_SRC_Y	O14976	GAK	P12931	SRC	Y371	G373S	373	Missense	proximal	2	no	22.598	23.726	EPSD	COSMIC	20.673	Up-regulation
TK_Src_SrcA_SRC_Y	O14976	GAK	P12931	SRC	Y371	E366K	366	Missense	distal	-5	no	22.598	22.022	EPSD	COSMIC;CCLE	20.673	Down-regulation
TK_Src_SrcA_SRC_Y	O14976	GAK	P12931	SRC	Y615	K617E	617	Missense	proximal	2	no	20.103	21.272	EPSD	COSMIC	20.673	Gain
TK_Src_SrcA_SRC_Y	O14976	GAK	P12931	SRC	Y764	T761A	761	Missense	distal	-3	no	21.459	21.264	EPSD	COSMIC	20.673	Down-regulation
TK_Src_SrcA_SRC_Y	O14976	GAK	P12931	SRC	Y764	S770F	770	Missense	distal	6	no	21.459	21.490	EPSD	COSMIC	20.673	Up-regulation
TK_Src_SrcA_SRC_Y	O14976	GAK	P12931	SRC	Y764	G767V	767	Missense	distal	3	no	21.459	21.836	EPSD	COSMIC	20.673	Up-regulation
TK_Src_SrcA_SRC_Y	P02786	TFRC	P12931	SRC	Y611	D610Y	610	Missense	proximal	-1	no	20.261	21.423	EPSD	COSMIC;GDSC;CCLE	20.673	Gain
TK_Src_SrcA_SRC_Y	O60331	PIP5K1C	P12931	SRC	Y649	L652F	652	Missense	distal	3	no	21.315	21.555	PhosphoSitePlus	COSMIC;CCLE	20.673	Up-regulation
TK_Src_SrcA_SRC_Y	O60331	PIP5K1C	P12931	SRC	Y649	H653P	653	Missense	distal	4	no	21.315	21.306	PhosphoSitePlus	COSMIC	20.673	Down-regulation
TK_Src_SrcA_SRC_Y	P34741	SDC2	P12931	SRC	Y179	R172T	172	Missense	distal	-7	no	21.440	21.288	PhosphoSitePlus	COSMIC	20.673	Down-regulation
TK_Src_SrcA_SRC_Y	P34741	SDC2	P12931	SRC	Y179	Y179N	179	Missense	central	0	yes	21.440	0.000	PhosphoSitePlus	COSMIC	20.673	Loss
TK_Src_SrcA_SRC_Y	P34741	SDC2	P12931	SRC	Y179	R184C	184	Missense	distal	5	no	21.440	21.874	PhosphoSitePlus	COSMIC	20.673	Up-regulation
TK_Src_SrcA_SRC_Y	P34741	SDC2	P12931	SRC	Y179	K173R	173	Missense	distal	-6	no	21.440	21.226	PhosphoSitePlus	COSMIC	20.673	Down-regulation
TK_Src_SrcA_SRC_Y	P34741	SDC2	P12931	SRC	Y179	E183K	183	Missense	distal	4	no	21.440	21.441	PhosphoSitePlus	COSMIC	20.673	Up-regulation
TK_Src_SrcA_SRC_Y	Q92558	WASF1	P12931	SRC	Y125	D126E	126	Missense	proximal	1	no	20.803	21.409	PhosphoSitePlus	COSMIC	20.673	Up-regulation
TK_Src_SrcA_SRC_Y	P22001	KCNA3	P12931	SRC	Y162	G166R	166	Missense	distal	4	no	20.763	20.761	EPSD	COSMIC	20.673	Down-regulation
TK_Src_SrcA_SRC_Y	P22001	KCNA3	P12931	SRC	Y162	S155R	155	Missense	distal	-7	no	20.763	21.011	EPSD	COSMIC	20.673	Up-regulation
TK_Src_SrcA_SRC_Y	P22001	KCNA3	P12931	SRC	Y499	S497Y	497	Missense	proximal	-2	no	21.715	21.167	PhosphoSitePlus;EPSD	COSMIC	20.673	Down-regulation
TK_Src_SrcA_SRC_Y	P22001	KCNA3	P12931	SRC	Y499	Y499H	499	Missense	central	0	yes	21.715	0.000	PhosphoSitePlus;EPSD	COSMIC	20.673	Loss
TK_Src_SrcA_SRC_Y	P22001	KCNA3	P12931	SRC	Y499	S497A	497	Missense	proximal	-2	no	21.715	21.348	PhosphoSitePlus;EPSD	COSMIC;GDSC;CCLE	20.673	Down-regulation
TK_Src_SrcA_SRC_Y	P22001	KCNA3	P12931	SRC	Y499	V502L	502	Missense	distal	3	no	21.715	21.742	PhosphoSitePlus;EPSD	COSMIC;GDSC;CCLE	20.673	Up-regulation
TK_Src_SrcA_SRC_Y	A1X283	SH3PXD2B	P12931	SRC	Y42	I41M	41	Missense	proximal	-1	no	23.015	21.784	EPSD	COSMIC	20.673	Down-regulation
TK_Src_SrcA_SRC_Y	A1X283	SH3PXD2B	P12931	SRC	Y508	D513H	513	Missense	distal	5	no	23.045	23.334	PhosphoSitePlus	COSMIC	20.673	Up-regulation
TK_Src_SrcA_SRC_Y	A1X283	SH3PXD2B	P12931	SRC	Y508	M502L	502	Missense	distal	-6	no	23.045	23.517	PhosphoSitePlus	COSMIC	20.673	Up-regulation
TK_Src_SrcA_SRC_Y	A1X283	SH3PXD2B	P12931	SRC	Y855	S853F	853	Missense	proximal	-2	no	21.160	20.179	EPSD	COSMIC	20.673	Loss
TK_Src_SrcA_SRC_Y	A1X283	SH3PXD2B	P12931	SRC	Y855	K851Q	851	Missense	distal	-4	no	21.160	21.499	EPSD	COSMIC	20.673	Up-regulation
TK_Src_SrcA_SRC_Y	P06493	CDK1	P12931	SRC	Y15	V18L	18	Missense	distal	3	no	24.693	24.720	PhosphoSitePlus	COSMIC	20.673	Up-regulation
TK_Src_SrcA_SRC_Y	P06493	CDK1	P12931	SRC	Y15	E12K	12	Missense	distal	-3	no	24.693	22.982	PhosphoSitePlus	COSMIC	20.673	Down-regulation
TK_Src_SrcA_SRC_Y	P06493	CDK1	P12931	SRC	Y15	Y15C	15	Missense	central	0	yes	24.693	0.000	PhosphoSitePlus	COSMIC	20.673	Loss
TK_Src_SrcA_SRC_Y	Q3V6T2	CCDC88A	P12931	SRC	Y1153	L1152F	1152	Missense	proximal	-1	no	21.553	20.694	EPSD	COSMIC	20.673	Down-regulation
TK_Src_SrcA_SRC_Y	Q3V6T2	CCDC88A	P12931	SRC	Y1153	S1151F	1151	Missense	proximal	-2	no	21.553	20.573	EPSD	COSMIC	20.673	Loss
TK_Src_SrcA_SRC_Y	Q3V6T2	CCDC88A	P12931	SRC	Y1153	D1148N	1148	Missense	distal	-5	no	21.553	21.341	EPSD	COSMIC	20.673	Down-regulation
TK_Src_SrcA_SRC_Y	Q3V6T2	CCDC88A	P12931	SRC	Y1153	K1158E	1158	Missense	distal	5	no	21.553	21.520	EPSD	COSMIC	20.673	Down-regulation
TK_Src_SrcA_SRC_Y	Q3V6T2	CCDC88A	P12931	SRC	Y1384	F1383V	1383	Missense	proximal	-1	no	18.841	20.810	EPSD	COSMIC	20.673	Gain
TK_Src_SrcA_SRC_Y	Q3V6T2	CCDC88A	P12931	SRC	Y1799	P1803S	1803	Missense	distal	4	no	23.042	23.064	EPSD;PhosphoSitePlus	COSMIC	20.673	Up-regulation
TK_Src_SrcA_SRC_Y	Q3V6T2	CCDC88A	P12931	SRC	Y1799	S1796C	1796	Missense	distal	-3	no	23.042	20.321	EPSD;PhosphoSitePlus	COSMIC	20.673	Loss
TK_Src_SrcA_SRC_Y	Q3V6T2	CCDC88A	P12931	SRC	Y1799	A1800E	1800	Missense	proximal	1	no	23.042	24.340	EPSD;PhosphoSitePlus	COSMIC	20.673	Up-regulation
TK_Src_SrcA_SRC_Y	Q3V6T2	CCDC88A	P12931	SRC	Y1799	R1804C	1804	Missense	distal	5	no	23.042	23.476	EPSD;PhosphoSitePlus	COSMIC	20.673	Up-regulation
TK_Src_SrcA_SRC_Y	Q3V6T2	CCDC88A	P12931	SRC	Y1799	P1798L	1798	Missense	proximal	-1	no	23.042	23.029	EPSD;PhosphoSitePlus	COSMIC	20.673	Down-regulation
TK_Src_SrcA_SRC_Y	P00338	LDHA	P12931	SRC	Y10	T3I	3	Missense	distal	-7	no	20.706	20.354	PhosphoSitePlus	COSMIC	20.673	Loss
TK_Src_SrcA_SRC_Y	P00338	LDHA	P12931	SRC	Y239	A238V	238	Missense	proximal	-1	no	20.609	21.945	EPSD	COSMIC	20.673	Gain
TK_Src_SrcA_SRC_Y	P00338	LDHA	P12931	SRC	Y239	I242F	242	Missense	distal	3	no	20.609	20.936	EPSD	COSMIC	20.673	Gain
TK_Src_SrcA_SRC_Y	P22681	CBL	P12931	SRC	Y141	R139T	139	Missense	proximal	-2	no	21.202	21.710	EPSD	COSMIC	20.673	Up-regulation
TK_Src_SrcA_SRC_Y	P22681	CBL	P12931	SRC	Y141	Y141C	141	Missense	central	0	yes	21.202	0.000	EPSD	COSMIC	20.673	Loss
TK_Src_SrcA_SRC_Y	P22681	CBL	P12931	SRC	Y368	M374V	374	Missense	distal	6	no	22.291	22.264	EPSD	COSMIC	20.673	Down-regulation
TK_Src_SrcA_SRC_Y	P22681	CBL	P12931	SRC	Y368	Y371S	371	Missense	distal	3	no	22.291	22.052	EPSD	COSMIC	20.673	Down-regulation
TK_Src_SrcA_SRC_Y	P22681	CBL	P12931	SRC	Y368	Y371N	371	Missense	distal	3	no	22.291	22.991	EPSD	COSMIC	20.673	Up-regulation
TK_Src_SrcA_SRC_Y	P22681	CBL	P12931	SRC	Y368	Q367P	367	Missense	proximal	-1	no	22.291	22.125	EPSD	COSMIC	20.673	Down-regulation
TK_Src_SrcA_SRC_Y	P22681	CBL	P12931	SRC	Y368	Y368N	368	Missense	central	0	yes	22.291	0.000	EPSD	COSMIC	20.673	Loss
TK_Src_SrcA_SRC_Y	P22681	CBL	P12931	SRC	Y368	Y371C	371	Missense	distal	3	no	22.291	21.216	EPSD	COSMIC	20.673	Down-regulation
TK_Src_SrcA_SRC_Y	P22681	CBL	P12931	SRC	Y368	Y371D	371	Missense	distal	3	no	22.291	21.916	EPSD	COSMIC	20.673	Down-regulation
TK_Src_SrcA_SRC_Y	P22681	CBL	P12931	SRC	Y368	Q367R	367	Missense	proximal	-1	no	22.291	20.459	EPSD	COSMIC	20.673	Loss
TK_Src_SrcA_SRC_Y	P22681	CBL	P12931	SRC	Y368	L370F	370	Missense	proximal	2	no	22.291	21.935	EPSD	COSMIC	20.673	Down-regulation
TK_Src_SrcA_SRC_Y	P22681	CBL	P12931	SRC	Y368	E366D	366	Missense	proximal	-2	no	22.291	22.004	EPSD	COSMIC	20.673	Down-regulation
TK_Src_SrcA_SRC_Y	P22681	CBL	P12931	SRC	Y368	E366Q	366	Missense	proximal	-2	no	22.291	21.102	EPSD	COSMIC	20.673	Down-regulation
TK_Src_SrcA_SRC_Y	P22681	CBL	P12931	SRC	Y368	G375P	375	Missense	distal	7	no	22.291	22.280	EPSD	COSMIC	20.673	Down-regulation
TK_Src_SrcA_SRC_Y	P22681	CBL	P12931	SRC	Y368	G375S	375	Missense	distal	7	no	22.291	22.260	EPSD	COSMIC	20.673	Down-regulation
TK_Src_SrcA_SRC_Y	P22681	CBL	P12931	SRC	Y371	M374V	374	Missense	distal	3	no	20.828	21.194	EPSD	COSMIC	20.673	Up-regulation
TK_Src_SrcA_SRC_Y	P22681	CBL	P12931	SRC	Y371	Y371S	371	Missense	central	0	yes	20.828	0.000	EPSD	COSMIC	20.673	Loss
TK_Src_SrcA_SRC_Y	P22681	CBL	P12931	SRC	Y371	Y371N	371	Missense	central	0	yes	20.828	0.000	EPSD	COSMIC	20.673	Loss
TK_Src_SrcA_SRC_Y	P22681	CBL	P12931	SRC	Y371	Q367P	367	Missense	distal	-4	no	20.828	20.884	EPSD	COSMIC	20.673	Up-regulation
TK_Src_SrcA_SRC_Y	P22681	CBL	P12931	SRC	Y371	Y368N	368	Missense	distal	-3	no	20.828	21.708	EPSD	COSMIC	20.673	Up-regulation
TK_Src_SrcA_SRC_Y	P22681	CBL	P12931	SRC	Y371	Y371C	371	Missense	central	0	yes	20.828	0.000	EPSD	COSMIC	20.673	Loss
TK_Src_SrcA_SRC_Y	P22681	CBL	P12931	SRC	Y371	Y371D	371	Missense	central	0	yes	20.828	0.000	EPSD	COSMIC	20.673	Loss
TK_Src_SrcA_SRC_Y	P22681	CBL	P12931	SRC	Y371	Q367R	367	Missense	distal	-4	no	20.828	21.207	EPSD	COSMIC	20.673	Up-regulation
TK_Src_SrcA_SRC_Y	P22681	CBL	P12931	SRC	Y371	S376F	376	Missense	distal	5	no	20.828	21.077	EPSD	COSMIC	20.673	Up-regulation
TK_Src_SrcA_SRC_Y	P22681	CBL	P12931	SRC	Y371	L370F	370	Missense	proximal	-1	no	20.828	19.968	EPSD	COSMIC	20.673	Loss
TK_Src_SrcA_SRC_Y	P22681	CBL	P12931	SRC	Y371	T377A	377	Missense	distal	6	no	20.828	20.841	EPSD	COSMIC	20.673	Up-regulation
TK_Src_SrcA_SRC_Y	P22681	CBL	P12931	SRC	Y371	E366D	366	Missense	distal	-5	no	20.828	20.727	EPSD	COSMIC	20.673	Down-regulation
TK_Src_SrcA_SRC_Y	P22681	CBL	P12931	SRC	Y371	E366Q	366	Missense	distal	-5	no	20.828	20.400	EPSD	COSMIC	20.673	Loss
TK_Src_SrcA_SRC_Y	P22681	CBL	P12931	SRC	Y371	G375P	375	Missense	distal	4	no	20.828	20.831	EPSD	COSMIC	20.673	Up-regulation
TK_Src_SrcA_SRC_Y	P22681	CBL	P12931	SRC	Y371	G375S	375	Missense	distal	4	no	20.828	20.852	EPSD	COSMIC	20.673	Up-regulation
TK_Src_SrcA_SRC_Y	P22681	CBL	P12931	SRC	Y455	E448Q	448	Missense	distal	-7	no	20.772	20.718	EPSD	COSMIC	20.673	Down-regulation
TK_Src_SrcA_SRC_Y	P22681	CBL	P12931	SRC	Y455	D456N	456	Missense	proximal	1	no	20.772	19.380	EPSD	COSMIC	20.673	Loss
TK_Src_SrcA_SRC_Y	P22681	CBL	P12931	SRC	Y455	N454D	454	Missense	proximal	-1	no	20.772	21.721	EPSD	COSMIC	20.673	Up-regulation
TK_Src_SrcA_SRC_Y	P22681	CBL	P12931	SRC	Y455	D458N	458	Missense	distal	3	no	20.772	21.847	EPSD	COSMIC	20.673	Up-regulation
TK_Src_SrcA_SRC_Y	P22681	CBL	P12931	SRC	Y455	G449V	449	Missense	distal	-6	no	20.772	20.665	EPSD	COSMIC	20.673	Loss
TK_Src_SrcA_SRC_Y	P22681	CBL	P12931	SRC	Y552	P547S	547	Missense	distal	-5	no	22.252	22.354	EPSD	COSMIC	20.673	Up-regulation
TK_Src_SrcA_SRC_Y	P22681	CBL	P12931	SRC	Y552	P548L	548	Missense	distal	-4	no	22.252	21.617	EPSD	COSMIC	20.673	Down-regulation
TK_Src_SrcA_SRC_Y	P22681	CBL	P12931	SRC	Y552	R550W	550	Missense	proximal	-2	no	22.252	21.302	EPSD	COSMIC	20.673	Down-regulation
TK_Src_SrcA_SRC_Y	P22681	CBL	P12931	SRC	Y552	S558F	558	Missense	distal	6	no	22.252	22.283	EPSD	COSMIC	20.673	Up-regulation
TK_Src_SrcA_SRC_Y	P22681	CBL	P12931	SRC	Y674	S675C	675	Missense	proximal	1	no	21.059	18.876	EPSD	COSMIC	20.673	Loss
TK_Src_SrcA_SRC_Y	P22681	CBL	P12931	SRC	Y674	A677V	677	Missense	distal	3	no	21.059	21.629	EPSD	COSMIC	20.673	Up-regulation
TK_Src_SrcA_SRC_Y	P22681	CBL	P12931	SRC	Y674	A678V	678	Missense	distal	4	no	21.059	21.032	EPSD	COSMIC	20.673	Down-regulation
TK_Src_SrcA_SRC_Y	P22681	CBL	P12931	SRC	Y674	A678T	678	Missense	distal	4	no	21.059	21.054	EPSD	COSMIC	20.673	Down-regulation
TK_Src_SrcA_SRC_Y	P22681	CBL	P12931	SRC	Y700	G694D	694	Missense	distal	-6	no	20.835	21.142	EPSD	COSMIC	20.673	Up-regulation
TK_Src_SrcA_SRC_Y	P22681	CBL	P12931	SRC	Y700	M701V	701	Missense	proximal	1	no	20.835	21.458	EPSD	COSMIC	20.673	Up-regulation
TK_Src_SrcA_SRC_Y	P22681	CBL	P12931	SRC	Y700	P703L	703	Missense	distal	3	no	20.835	20.737	EPSD	COSMIC	20.673	Down-regulation
TK_Src_SrcA_SRC_Y	P22681	CBL	P12931	SRC	Y700	S704C	704	Missense	distal	4	no	20.835	20.810	EPSD	COSMIC	20.673	Down-regulation
TK_Src_SrcA_SRC_Y	P22681	CBL	P12931	SRC	Y700	P707L	707	Missense	distal	7	no	20.835	20.829	EPSD	COSMIC	20.673	Down-regulation
TK_Src_SrcA_SRC_Y	P22681	CBL	P12931	SRC	Y700	S705C	705	Missense	distal	5	no	20.835	21.293	EPSD	COSMIC	20.673	Up-regulation
TK_Src_SrcA_SRC_Y	P22681	CBL	P12931	SRC	Y700	R706T	706	Missense	distal	6	no	20.835	20.831	EPSD	COSMIC	20.673	Down-regulation
TK_Src_SrcA_SRC_Y	P22681	CBL	P12931	SRC	Y731	S728N	728	Missense	distal	-3	no	22.875	22.835	EPSD;PhosphoSitePlus	COSMIC	20.673	Down-regulation
TK_Src_SrcA_SRC_Y	P22681	CBL	P12931	SRC	Y731	Y731C	731	Missense	central	0	yes	22.875	0.000	EPSD;PhosphoSitePlus	COSMIC	20.673	Loss
TK_Src_SrcA_SRC_Y	O14920	IKBKB	P12931	SRC	Y294	K301N	301	Missense	distal	7	no	24.919	24.874	EPSD	COSMIC	20.673	Down-regulation
TK_Src_SrcA_SRC_Y	O14920	IKBKB	P12931	SRC	Y294	R288S	288	Missense	distal	-6	no	24.919	25.059	EPSD	COSMIC	20.673	Up-regulation
TK_Src_SrcA_SRC_Y	Q07954	LRP1	P12931	SRC	Y1937	G1942C	1942	Missense	distal	5	no	22.490	22.743	EPSD	COSMIC	20.673	Up-regulation
TK_Src_SrcA_SRC_Y	Q07954	LRP1	P12931	SRC	Y2000	R1999C	1999	Missense	proximal	-1	no	19.495	20.917	EPSD	COSMIC	20.673	Gain
TK_Src_SrcA_SRC_Y	Q07954	LRP1	P12931	SRC	Y4473	G4479E	4479	Missense	distal	6	no	21.485	21.495	PhosphoSitePlus;EPSD	COSMIC	20.673	Up-regulation
TK_Src_SrcA_SRC_Y	Q07954	LRP1	P12931	SRC	Y4507	V4506M	4506	Missense	proximal	-1	no	23.612	22.006	EPSD;PhosphoSitePlus	COSMIC	20.673	Down-regulation
TK_Src_SrcA_SRC_Y	Q07954	LRP1	P12931	SRC	Y4507	L4510F	4510	Missense	distal	3	no	23.612	23.852	EPSD;PhosphoSitePlus	COSMIC	20.673	Up-regulation
TK_Src_SrcA_SRC_Y	Q07954	LRP1	P12931	SRC	Y4507	A4508T	4508	Missense	proximal	1	no	23.612	23.157	EPSD;PhosphoSitePlus	COSMIC	20.673	Down-regulation
TK_Src_SrcA_SRC_Y	Q16625	OCLN	P12931	SRC	Y29	P24A	24	Missense	distal	-5	no	21.526	21.530	EPSD	COSMIC	20.673	Up-regulation
TK_Src_SrcA_SRC_Y	Q16625	OCLN	P12931	SRC	Y287	E284K	284	Missense	distal	-3	no	21.127	19.416	EPSD	COSMIC	20.673	Loss
TK_Src_SrcA_SRC_Y	Q16625	OCLN	P12931	SRC	Y342	R335Q	335	Missense	distal	-7	no	21.477	21.253	EPSD	COSMIC	20.673	Down-regulation
TK_Src_SrcA_SRC_Y	Q16625	OCLN	P12931	SRC	Y368	G372D	372	Missense	distal	4	no	20.918	20.958	EPSD	COSMIC	20.673	Up-regulation
TK_Src_SrcA_SRC_Y	Q99439	CNN2	P12931	SRC	Y303	P297L	297	Missense	distal	-6	no	21.700	21.680	EPSD	COSMIC	20.673	Down-regulation
TK_Src_SrcA_SRC_Y	Q99439	CNN2	P12931	SRC	Y303	E306Q	306	Missense	distal	3	no	21.700	21.106	EPSD	COSMIC	20.673	Down-regulation
TK_Src_SrcA_SRC_Y	Q99439	CNN2	P12931	SRC	Y303	P301L	301	Missense	proximal	-2	no	21.700	20.170	EPSD	COSMIC	20.673	Loss
TK_Src_SrcA_SRC_Y	Q99439	CNN2	P12931	SRC	Y303	P301H	301	Missense	proximal	-2	no	21.700	21.035	EPSD	COSMIC	20.673	Down-regulation
TK_Src_SrcA_SRC_Y	Q969H4	CNKSR1	P12931	SRC	Y519	A524S	524	Missense	distal	5	no	25.825	25.870	EPSD;PhosphoSitePlus	COSMIC	20.673	Up-regulation
TK_Src_SrcA_SRC_Y	Q969H4	CNKSR1	P12931	SRC	Y519	E525D	525	Missense	distal	6	no	25.825	25.775	EPSD;PhosphoSitePlus	COSMIC	20.673	Down-regulation
TK_Src_SrcA_SRC_Y	Q969H4	CNKSR1	P12931	SRC	Y519	E523K	523	Missense	distal	4	no	25.825	25.826	EPSD;PhosphoSitePlus	COSMIC	20.673	Up-regulation
TK_Src_SrcA_SRC_Y	Q969H4	CNKSR1	P12931	SRC	Y519	E521K	521	Missense	proximal	2	no	25.825	24.656	EPSD;PhosphoSitePlus	COSMIC	20.673	Down-regulation
TK_Src_SrcA_SRC_Y	Q969H4	CNKSR1	P12931	SRC	Y519	P512Q	512	Missense	distal	-7	no	25.825	25.969	EPSD;PhosphoSitePlus	COSMIC	20.673	Up-regulation
TK_Src_SrcA_SRC_Y	Q969H4	CNKSR1	P12931	SRC	Y519	E515K	515	Missense	distal	-4	no	25.825	24.655	EPSD;PhosphoSitePlus	COSMIC	20.673	Down-regulation
TK_Src_SrcA_SRC_Y	Q969H4	CNKSR1	P12931	SRC	Y665	G670E	670	Missense	distal	5	no	21.467	21.310	EPSD;PhosphoSitePlus	COSMIC	20.673	Down-regulation
TK_Src_SrcA_SRC_Y	Q969H4	CNKSR1	P12931	SRC	Y665	R662L	662	Missense	distal	-3	no	21.467	20.272	EPSD;PhosphoSitePlus	COSMIC	20.673	Loss
TK_Src_SrcA_SRC_Y	Q969H4	CNKSR1	P12931	SRC	Y665	R662Q	662	Missense	distal	-3	no	21.467	22.083	EPSD;PhosphoSitePlus	COSMIC	20.673	Up-regulation
TK_Src_SrcA_SRC_Y	Q969H4	CNKSR1	P12931	SRC	Y665	S666L	666	Missense	proximal	1	no	21.467	19.921	EPSD;PhosphoSitePlus	COSMIC	20.673	Loss
TK_Src_SrcA_SRC_Y	P16591	FER	P12931	SRC	Y42	N48K	48	Missense	distal	6	no	22.321	22.365	EPSD	COSMIC	20.673	Up-regulation
TK_Src_SrcA_SRC_Y	P16591	FER	P12931	SRC	Y42	Q47K	47	Missense	distal	5	no	22.321	22.353	EPSD	COSMIC	20.673	Up-regulation
TK_Src_SrcA_SRC_Y	P16591	FER	P12931	SRC	Y199	Y200D	200	Missense	proximal	1	no	20.473	20.872	EPSD	COSMIC	20.673	Gain
TK_Src_SrcA_SRC_Y	Q00610	CLTC	P12931	SRC	Y377	E379K	379	Missense	proximal	2	no	20.794	19.624	EPSD	COSMIC	20.673	Loss
TK_Src_SrcA_SRC_Y	Q00610	CLTC	P12931	SRC	Y377	S378L	378	Missense	proximal	1	no	20.794	19.248	EPSD	COSMIC	20.673	Loss
TK_Src_SrcA_SRC_Y	Q00610	CLTC	P12931	SRC	Y377	F372C	372	Missense	distal	-5	no	20.794	20.314	EPSD	COSMIC	20.673	Loss
TK_Src_SrcA_SRC_Y	Q00610	CLTC	P12931	SRC	Y899	G906V	906	Missense	distal	7	no	24.562	24.596	EPSD	COSMIC	20.673	Up-regulation
TK_Src_SrcA_SRC_Y	Q00610	CLTC	P12931	SRC	Y899	R892K	892	Missense	distal	-7	no	24.562	24.228	EPSD	COSMIC;GDSC;CCLE	20.673	Down-regulation
TK_Src_SrcA_SRC_Y	Q00610	CLTC	P12931	SRC	Y900	G906V	906	Missense	distal	6	no	23.371	23.365	EPSD	COSMIC	20.673	Down-regulation
TK_Src_SrcA_SRC_Y	Q00610	CLTC	P12931	SRC	Y1137	Q1142R	1142	Missense	distal	5	no	21.484	21.459	EPSD	COSMIC	20.673	Down-regulation
TK_Src_SrcA_SRC_Y	Q00610	CLTC	P12931	SRC	Y1137	D1132G	1132	Missense	distal	-5	no	21.484	21.331	EPSD	COSMIC	20.673	Down-regulation
TK_Src_SrcA_SRC_Y	Q00610	CLTC	P12931	SRC	Y1137	Q1142H	1142	Missense	distal	5	no	21.484	21.564	EPSD	COSMIC;GDSC;CCLE	20.673	Up-regulation
TK_Src_SrcA_SRC_Y	Q00610	CLTC	P12931	SRC	Y1168	I1174M	1174	Missense	distal	6	no	21.336	21.357	EPSD	COSMIC;GDSC;CCLE	20.673	Up-regulation
TK_Src_SrcA_SRC_Y	Q00610	CLTC	P12931	SRC	Y1168	E1166Q	1166	Missense	proximal	-2	no	21.336	20.146	EPSD	COSMIC	20.673	Loss
TK_Src_SrcA_SRC_Y	Q00610	CLTC	P12931	SRC	Y1168	E1170Q	1170	Missense	proximal	2	no	21.336	21.027	EPSD	COSMIC	20.673	Down-regulation
TK_Src_SrcA_SRC_Y	Q00610	CLTC	P12931	SRC	Y1206	R1204C	1204	Missense	proximal	-2	no	20.975	20.480	EPSD	COSMIC	20.673	Loss
TK_Src_SrcA_SRC_Y	Q00610	CLTC	P12931	SRC	Y1206	Q1199K	1199	Missense	distal	-7	no	20.975	20.866	EPSD	COSMIC	20.673	Down-regulation
TK_Src_SrcA_SRC_Y	Q00610	CLTC	P12931	SRC	Y1206	D1207G	1207	Missense	proximal	1	no	20.975	20.597	EPSD	COSMIC	20.673	Loss
TK_Src_SrcA_SRC_Y	Q00610	CLTC	P12931	SRC	Y1477	F1471C	1471	Missense	distal	-6	no	22.715	22.315	PhosphoSitePlus	COSMIC;GDSC;CCLE	20.673	Down-regulation
TK_Src_SrcA_SRC_Y	Q00610	CLTC	P12931	SRC	Y1477	I1484V	1484	Missense	distal	7	no	22.715	22.741	PhosphoSitePlus	COSMIC	20.673	Up-regulation
TK_Src_SrcA_SRC_Y	Q00610	CLTC	P12931	SRC	Y1477	A1479S	1479	Missense	proximal	2	no	22.715	23.068	PhosphoSitePlus	COSMIC	20.673	Up-regulation
TK_Src_SrcA_SRC_Y	Q00610	CLTC	P12931	SRC	Y1487	I1484V	1484	Missense	distal	-3	no	19.954	21.059	EPSD	COSMIC	20.673	Gain
TK_Src_SrcA_SRC_Y	Q00610	CLTC	P12931	SRC	Y1634	G1635C	1635	Missense	proximal	1	no	20.961	18.664	EPSD	COSMIC	20.673	Loss
TK_Src_SrcA_SRC_Y	Q9NZC7	WWOX	P12931	SRC	Y33	T26P	26	Missense	distal	-7	no	25.105	24.888	PhosphoSitePlus	COSMIC	20.673	Down-regulation
TK_Src_SrcA_SRC_Y	Q9NZC7	WWOX	P12931	SRC	Y33	T26A	26	Missense	distal	-7	no	25.105	24.685	PhosphoSitePlus	COSMIC	20.673	Down-regulation
TK_Src_SrcA_SRC_Y	Q9NZC7	WWOX	P12931	SRC	Y33	E40V	40	Missense	distal	7	no	25.105	25.163	PhosphoSitePlus	COSMIC	20.673	Up-regulation
TK_Src_SrcA_SRC_Y	Q9NZC7	WWOX	P12931	SRC	Y33	N36Y	36	Missense	distal	3	no	25.105	24.405	PhosphoSitePlus	COSMIC	20.673	Down-regulation
TK_Src_SrcA_SRC_Y	Q9NZC7	WWOX	P12931	SRC	Y33	T38A	38	Missense	distal	5	no	25.105	24.890	PhosphoSitePlus	COSMIC	20.673	Down-regulation
TK_Src_SrcA_SRC_Y	P35637	FUS	P12931	SRC	Y239	S235N	235	Missense	distal	-4	no	20.602	21.017	EPSD	COSMIC	20.673	Gain
TK_Src_SrcA_SRC_Y	P04637	TP53	P12931	SRC	Y220	V216A	216	Missense	distal	-4	no	22.082	22.215	EPSD;PhosphoSitePlus	COSMIC	20.673	Up-regulation
TK_Src_SrcA_SRC_Y	P04637	TP53	P12931	SRC	Y220	P223S	223	Missense	distal	3	no	22.082	21.343	EPSD;PhosphoSitePlus	COSMIC	20.673	Down-regulation
TK_Src_SrcA_SRC_Y	P04637	TP53	P12931	SRC	Y220	P223L	223	Missense	distal	3	no	22.082	21.984	EPSD;PhosphoSitePlus	COSMIC;GDSC;CCLE	20.673	Down-regulation
TK_Src_SrcA_SRC_Y	P04637	TP53	P12931	SRC	Y220	V217A	217	Missense	distal	-3	no	22.082	22.633	EPSD;PhosphoSitePlus	COSMIC	20.673	Up-regulation
TK_Src_SrcA_SRC_Y	P04637	TP53	P12931	SRC	Y220	G226V	226	Missense	distal	6	no	22.082	22.075	EPSD;PhosphoSitePlus	COSMIC	20.673	Down-regulation
TK_Src_SrcA_SRC_Y	P04637	TP53	P12931	SRC	Y220	P222S	222	Missense	proximal	2	no	22.082	22.689	EPSD;PhosphoSitePlus	COSMIC	20.673	Up-regulation
TK_Src_SrcA_SRC_Y	P04637	TP53	P12931	SRC	Y220	P219L	219	Missense	proximal	-1	no	22.082	22.068	EPSD;PhosphoSitePlus	COSMIC	20.673	Down-regulation
TK_Src_SrcA_SRC_Y	P04637	TP53	P12931	SRC	Y220	G226D	226	Missense	distal	6	no	22.082	22.041	EPSD;PhosphoSitePlus	COSMIC	20.673	Down-regulation
TK_Src_SrcA_SRC_Y	P04637	TP53	P12931	SRC	Y220	V218M	218	Missense	proximal	-2	no	22.082	21.410	EPSD;PhosphoSitePlus	COSMIC	20.673	Down-regulation
TK_Src_SrcA_SRC_Y	P04637	TP53	P12931	SRC	Y220	E224G	224	Missense	distal	4	no	22.082	22.069	EPSD;PhosphoSitePlus	COSMIC	20.673	Down-regulation
TK_Src_SrcA_SRC_Y	P04637	TP53	P12931	SRC	Y220	G226A	226	Missense	distal	6	no	22.082	22.066	EPSD;PhosphoSitePlus	COSMIC	20.673	Down-regulation
TK_Src_SrcA_SRC_Y	P04637	TP53	P12931	SRC	Y220	H214Q	214	Missense	distal	-6	no	22.082	22.217	EPSD;PhosphoSitePlus	COSMIC	20.673	Up-regulation
TK_Src_SrcA_SRC_Y	P04637	TP53	P12931	SRC	Y220	P219H	219	Missense	proximal	-1	no	22.082	22.312	EPSD;PhosphoSitePlus	COSMIC	20.673	Up-regulation
TK_Src_SrcA_SRC_Y	P04637	TP53	P12931	SRC	Y220	R213W	213	Missense	distal	-7	no	22.082	21.609	EPSD;PhosphoSitePlus	COSMIC	20.673	Down-regulation
TK_Src_SrcA_SRC_Y	P04637	TP53	P12931	SRC	Y220	V218A	218	Missense	proximal	-2	no	22.082	22.379	EPSD;PhosphoSitePlus	COSMIC	20.673	Up-regulation
TK_Src_SrcA_SRC_Y	P04637	TP53	P12931	SRC	Y220	S227F	227	Missense	distal	7	no	22.082	22.109	EPSD;PhosphoSitePlus	COSMIC	20.673	Up-regulation
TK_Src_SrcA_SRC_Y	P04637	TP53	P12931	SRC	Y220	S215C	215	Missense	distal	-5	no	22.082	21.278	EPSD;PhosphoSitePlus	COSMIC;GDSC;CCLE	20.673	Down-regulation
TK_Src_SrcA_SRC_Y	P04637	TP53	P12931	SRC	Y220	V225I	225	Missense	distal	5	no	22.082	22.132	EPSD;PhosphoSitePlus	COSMIC	20.673	Up-regulation
TK_Src_SrcA_SRC_Y	P04637	TP53	P12931	SRC	Y220	P223H	223	Missense	distal	3	no	22.082	21.485	EPSD;PhosphoSitePlus	COSMIC	20.673	Down-regulation
TK_Src_SrcA_SRC_Y	P04637	TP53	P12931	SRC	Y220	V218L	218	Missense	proximal	-2	no	22.082	22.001	EPSD;PhosphoSitePlus	COSMIC;GDSC;CCLE	20.673	Down-regulation
TK_Src_SrcA_SRC_Y	P04637	TP53	P12931	SRC	Y220	P222T	222	Missense	proximal	2	no	22.082	22.430	EPSD;PhosphoSitePlus	COSMIC	20.673	Up-regulation
TK_Src_SrcA_SRC_Y	P04637	TP53	P12931	SRC	Y220	V225A	225	Missense	distal	5	no	22.082	21.940	EPSD;PhosphoSitePlus	COSMIC	20.673	Down-regulation
TK_Src_SrcA_SRC_Y	P04637	TP53	P12931	SRC	Y220	V225F	225	Missense	distal	5	no	22.082	22.234	EPSD;PhosphoSitePlus	COSMIC	20.673	Up-regulation
TK_Src_SrcA_SRC_Y	P04637	TP53	P12931	SRC	Y220	E224K	224	Missense	distal	4	no	22.082	22.083	EPSD;PhosphoSitePlus	COSMIC;GDSC;CCLE	20.673	Up-regulation
TK_Src_SrcA_SRC_Y	P04637	TP53	P12931	SRC	Y220	V225G	225	Missense	distal	5	no	22.082	22.191	EPSD;PhosphoSitePlus	COSMIC	20.673	Up-regulation
TK_Src_SrcA_SRC_Y	P04637	TP53	P12931	SRC	Y220	E221G	221	Missense	proximal	1	no	22.082	21.098	EPSD;PhosphoSitePlus	COSMIC	20.673	Down-regulation
TK_Src_SrcA_SRC_Y	P04637	TP53	P12931	SRC	Y220	E221D	221	Missense	proximal	1	no	22.082	21.476	EPSD;PhosphoSitePlus	COSMIC	20.673	Down-regulation
TK_Src_SrcA_SRC_Y	P04637	TP53	P12931	SRC	Y220	V217E	217	Missense	distal	-3	no	22.082	23.961	EPSD;PhosphoSitePlus	COSMIC	20.673	Up-regulation
TK_Src_SrcA_SRC_Y	P04637	TP53	P12931	SRC	Y220	P222L	222	Missense	proximal	2	no	22.082	21.625	EPSD;PhosphoSitePlus	COSMIC	20.673	Down-regulation
TK_Src_SrcA_SRC_Y	P04637	TP53	P12931	SRC	Y220	P219R	219	Missense	proximal	-1	no	22.082	20.416	EPSD;PhosphoSitePlus	COSMIC	20.673	Loss
TK_Src_SrcA_SRC_Y	P04637	TP53	P12931	SRC	Y220	P219S	219	Missense	proximal	-1	no	22.082	21.730	EPSD;PhosphoSitePlus	COSMIC	20.673	Down-regulation
TK_Src_SrcA_SRC_Y	P04637	TP53	P12931	SRC	Y220	P222Q	222	Missense	proximal	2	no	22.082	22.207	EPSD;PhosphoSitePlus	COSMIC	20.673	Up-regulation
TK_Src_SrcA_SRC_Y	P04637	TP53	P12931	SRC	Y220	P222A	222	Missense	proximal	2	no	22.082	22.337	EPSD;PhosphoSitePlus	COSMIC	20.673	Up-regulation
TK_Src_SrcA_SRC_Y	P04637	TP53	P12931	SRC	Y220	G226S	226	Missense	distal	6	no	22.082	22.062	EPSD;PhosphoSitePlus	COSMIC	20.673	Down-regulation
TK_Src_SrcA_SRC_Y	P04637	TP53	P12931	SRC	Y220	V217L	217	Missense	distal	-3	no	22.082	21.270	EPSD;PhosphoSitePlus	COSMIC	20.673	Down-regulation
TK_Src_SrcA_SRC_Y	P04637	TP53	P12931	SRC	Y220	P223A	223	Missense	distal	3	no	22.082	21.387	EPSD;PhosphoSitePlus	COSMIC	20.673	Down-regulation
TK_Src_SrcA_SRC_Y	P04637	TP53	P12931	SRC	Y220	S227Y	227	Missense	distal	7	no	22.082	22.069	EPSD;PhosphoSitePlus	COSMIC	20.673	Down-regulation
TK_Src_SrcA_SRC_Y	P04637	TP53	P12931	SRC	Y220	V217M	217	Missense	distal	-3	no	22.082	21.599	EPSD;PhosphoSitePlus	COSMIC	20.673	Down-regulation
TK_Src_SrcA_SRC_Y	P04637	TP53	P12931	SRC	Y220	V225D	225	Missense	distal	5	no	22.082	21.826	EPSD;PhosphoSitePlus	COSMIC	20.673	Down-regulation
TK_Src_SrcA_SRC_Y	P04637	TP53	P12931	SRC	Y220	E224V	224	Missense	distal	4	no	22.082	22.065	EPSD;PhosphoSitePlus	COSMIC	20.673	Down-regulation
TK_Src_SrcA_SRC_Y	P04637	TP53	P12931	SRC	Y220	H214P	214	Missense	distal	-6	no	22.082	22.206	EPSD;PhosphoSitePlus	COSMIC	20.673	Up-regulation
TK_Src_SrcA_SRC_Y	P04637	TP53	P12931	SRC	Y220	P219C	219	Missense	proximal	-1	no	22.082	21.838	EPSD;PhosphoSitePlus	COSMIC	20.673	Down-regulation
TK_Src_SrcA_SRC_Y	P04637	TP53	P12931	SRC	Y220	E224Q	224	Missense	distal	4	no	22.082	22.090	EPSD;PhosphoSitePlus	COSMIC	20.673	Up-regulation
TK_Src_SrcA_SRC_Y	P04637	TP53	P12931	SRC	Y220	Y220L	220	Missense	central	0	yes	22.082	0.000	EPSD;PhosphoSitePlus	COSMIC	20.673	Loss
TK_Src_SrcA_SRC_Y	P04637	TP53	P12931	SRC	Y220	Y220X	220	Missense	central	0	yes	22.082	0.000	EPSD;PhosphoSitePlus	COSMIC	20.673	Loss
TK_Src_SrcA_SRC_Y	P04637	TP53	P12931	SRC	Y220	H214A	214	Missense	distal	-6	no	22.082	22.165	EPSD;PhosphoSitePlus	COSMIC	20.673	Up-regulation
TK_Src_SrcA_SRC_Y	P04637	TP53	P12931	SRC	Y327	L323R	323	Missense	distal	-4	no	20.561	21.519	EPSD	COSMIC	20.673	Gain
TK_Src_SrcA_SRC_Y	P04637	TP53	P12931	SRC	Y327	G325E	325	Missense	proximal	-2	no	20.561	21.138	EPSD	COSMIC	20.673	Gain
TK_Src_SrcA_SRC_Y	P04637	TP53	P12931	SRC	Y327	F328S	328	Missense	proximal	1	no	20.561	22.438	EPSD	COSMIC	20.673	Gain
TK_Src_SrcA_SRC_Y	P04637	TP53	P12931	SRC	Y327	L323P	323	Missense	distal	-4	no	20.561	21.196	EPSD	COSMIC	20.673	Gain
TK_Src_SrcA_SRC_Y	P04637	TP53	P12931	SRC	Y327	L323V	323	Missense	distal	-4	no	20.561	20.720	EPSD	COSMIC	20.673	Gain
TK_Src_SrcA_SRC_Y	P04637	TP53	P12931	SRC	Y327	L323G	323	Missense	distal	-4	no	20.561	21.537	EPSD	COSMIC	20.673	Gain
TK_Src_SrcA_SRC_Y	P04637	TP53	P12931	SRC	Y327	F328V	328	Missense	proximal	1	no	20.561	21.655	EPSD	COSMIC	20.673	Gain
TK_Src_SrcA_SRC_Y	P04637	TP53	P12931	SRC	Y327	L330F	330	Missense	distal	3	no	20.561	20.801	EPSD	COSMIC	20.673	Gain
TK_Src_SrcA_SRC_Y	Q13283	G3BP1	P12931	SRC	Y20	Y19H	19	Missense	proximal	-1	no	20.808	20.213	EPSD	COSMIC;GDSC;CCLE	20.673	Loss
TK_Src_SrcA_SRC_Y	Q13283	G3BP1	P12931	SRC	Y20	R13L	13	Missense	distal	-7	no	20.808	20.325	EPSD	COSMIC	20.673	Loss
TK_Src_SrcA_SRC_Y	P11802	CDK4	P12931	SRC	Y17	A10D	10	Missense	distal	-7	no	22.818	23.191	PhosphoSitePlus	COSMIC	20.673	Up-regulation
TK_Src_SrcA_SRC_Y	P11802	CDK4	P12931	SRC	Y17	K22R	22	Missense	distal	5	no	22.818	22.761	PhosphoSitePlus	COSMIC	20.673	Down-regulation
TK_Src_SrcA_SRC_Y	P11802	CDK4	P12931	SRC	Y17	A23T	23	Missense	distal	6	no	22.818	22.804	PhosphoSitePlus	COSMIC	20.673	Down-regulation
TK_Src_SrcA_SRC_Y	P35968	KDR	P12931	SRC	Y224	P230L	230	Missense	distal	6	no	20.745	20.761	EPSD	COSMIC;GDSC;CCLE	20.673	Up-regulation
TK_Src_SrcA_SRC_Y	P35968	KDR	P12931	SRC	Y224	D225Y	225	Missense	proximal	1	no	20.745	20.346	EPSD	COSMIC	20.673	Loss
TK_Src_SrcA_SRC_Y	P35968	KDR	P12931	SRC	Y224	D225N	225	Missense	proximal	1	no	20.745	19.353	EPSD	COSMIC	20.673	Loss
TK_Src_SrcA_SRC_Y	P35968	KDR	P12931	SRC	Y224	V219L	219	Missense	distal	-5	no	20.745	20.584	EPSD	COSMIC	20.673	Loss
TK_Src_SrcA_SRC_Y	P35968	KDR	P12931	SRC	Y224	S231Y	231	Missense	distal	7	no	20.745	20.732	EPSD	COSMIC	20.673	Down-regulation
TK_Src_SrcA_SRC_Y	P35968	KDR	P12931	SRC	Y224	Y224D	224	Missense	central	0	yes	20.745	0.000	EPSD	COSMIC	20.673	Loss
TK_Src_SrcA_SRC_Y	P35968	KDR	P12931	SRC	Y224	V226M	226	Missense	proximal	2	no	20.745	20.480	EPSD	COSMIC	20.673	Loss
TK_Src_SrcA_SRC_Y	P35968	KDR	P12931	SRC	Y822	R819Q	819	Missense	distal	-3	no	20.611	21.227	EPSD	COSMIC	20.673	Gain
TK_Src_SrcA_SRC_Y	P35968	KDR	P12931	SRC	Y822	H816Y	816	Missense	distal	-6	no	20.611	20.780	EPSD	COSMIC	20.673	Gain
TK_Src_SrcA_SRC_Y	P35968	KDR	P12931	SRC	Y996	E990G	990	Missense	distal	-6	no	23.116	22.887	EPSD	COSMIC	20.673	Down-regulation
TK_Src_SrcA_SRC_Y	P35968	KDR	P12931	SRC	Y996	E993K	993	Missense	distal	-3	no	23.116	21.405	EPSD	COSMIC	20.673	Down-regulation
TK_Src_SrcA_SRC_Y	P35968	KDR	P12931	SRC	Y996	K997R	997	Missense	proximal	1	no	23.116	23.534	EPSD	COSMIC	20.673	Up-regulation
TK_Src_SrcA_SRC_Y	P35968	KDR	P12931	SRC	Y1059	R1066H	1066	Missense	distal	7	no	21.285	21.271	EPSD	COSMIC	20.673	Down-regulation
TK_Src_SrcA_SRC_Y	P35968	KDR	P12931	SRC	Y1059	P1057S	1057	Missense	proximal	-2	no	21.285	20.499	EPSD	COSMIC	20.673	Loss
TK_Src_SrcA_SRC_Y	P35968	KDR	P12931	SRC	Y1059	A1065T	1065	Missense	distal	6	no	21.285	21.271	EPSD	COSMIC;GDSC	20.673	Down-regulation
TK_Src_SrcA_SRC_Y	P35968	KDR	P12931	SRC	Y1059	G1063R	1063	Missense	distal	4	no	21.285	21.284	EPSD	COSMIC	20.673	Down-regulation
TK_Src_SrcA_SRC_Y	P35968	KDR	P12931	SRC	Y1059	D1064Y	1064	Missense	distal	5	no	21.285	21.857	EPSD	COSMIC;GDSC;CCLE	20.673	Up-regulation
TK_Src_SrcA_SRC_Y	P35968	KDR	P12931	SRC	Y1175	D1174E	1174	Missense	proximal	-1	no	20.848	21.757	PhosphoSitePlus	COSMIC	20.673	Up-regulation
TK_Src_SrcA_SRC_Y	P35968	KDR	P12931	SRC	Y1175	D1174N	1174	Missense	proximal	-1	no	20.848	19.898	PhosphoSitePlus	COSMIC	20.673	Loss
TK_Src_SrcA_SRC_Y	P35968	KDR	P12931	SRC	Y1175	G1172S	1172	Missense	distal	-3	no	20.848	21.028	PhosphoSitePlus	COSMIC	20.673	Up-regulation
TK_Src_SrcA_SRC_Y	P35968	KDR	P12931	SRC	Y1175	A1168S	1168	Missense	distal	-7	no	20.848	21.172	PhosphoSitePlus	COSMIC	20.673	Up-regulation
TK_Src_SrcA_SRC_Y	P35968	KDR	P12931	SRC	Y1175	A1168V	1168	Missense	distal	-7	no	20.848	20.899	PhosphoSitePlus	COSMIC	20.673	Up-regulation
TK_Src_SrcA_SRC_Y	P35968	KDR	P12931	SRC	Y1175	E1182D	1182	Missense	distal	7	no	20.848	20.809	PhosphoSitePlus	COSMIC	20.673	Down-regulation
TK_Src_SrcA_SRC_Y	P35968	KDR	P12931	SRC	Y1175	A1168D	1168	Missense	distal	-7	no	20.848	21.220	PhosphoSitePlus	COSMIC	20.673	Up-regulation
TK_Src_SrcA_SRC_Y	P35968	KDR	P12931	SRC	Y1175	S1181L	1181	Missense	distal	6	no	20.848	20.879	PhosphoSitePlus	COSMIC	20.673	Up-regulation
TK_Src_SrcA_SRC_Y	P35968	KDR	P12931	SRC	Y1175	D1171N	1171	Missense	distal	-4	no	20.848	20.315	PhosphoSitePlus	COSMIC	20.673	Loss
TK_Src_SrcA_SRC_Y	P35968	KDR	P12931	SRC	Y1214	C1208Y	1208	Missense	distal	-6	no	20.456	20.990	EPSD	COSMIC	20.673	Gain
TK_Src_SrcA_SRC_Y	P35968	KDR	P12931	SRC	Y1309	H1310Y	1310	Missense	proximal	1	no	21.429	22.476	EPSD	COSMIC	20.673	Up-regulation
TK_Src_SrcA_SRC_Y	P35968	KDR	P12931	SRC	Y1309	S1311F	1311	Missense	proximal	2	no	21.429	20.009	EPSD	COSMIC	20.673	Loss
TK_Src_SrcA_SRC_Y	P35968	KDR	P12931	SRC	Y1309	D1313N	1313	Missense	distal	4	no	21.429	21.445	EPSD	COSMIC	20.673	Up-regulation
TK_Src_SrcA_SRC_Y	P35968	KDR	P12931	SRC	Y1309	G1304C	1304	Missense	distal	-5	no	21.429	20.694	EPSD	COSMIC;GDSC;CCLE	20.673	Down-regulation
TK_Src_SrcA_SRC_Y	P35968	KDR	P12931	SRC	Y1309	T1316P	1316	Missense	distal	7	no	21.429	21.479	EPSD	COSMIC	20.673	Up-regulation
TK_Src_SrcA_SRC_Y	P35968	KDR	P12931	SRC	Y1309	Y1309D	1309	Missense	central	0	yes	21.429	0.000	EPSD	COSMIC	20.673	Loss
TK_Src_SrcA_SRC_Y	P35968	KDR	P12931	SRC	Y1309	S1303N	1303	Missense	distal	-6	no	21.429	21.402	EPSD	COSMIC;GDSC;CCLE	20.673	Down-regulation
TK_Src_SrcA_SRC_Y	P35968	KDR	P12931	SRC	Y1309	G1308R	1308	Missense	proximal	-1	no	21.429	20.658	EPSD	COSMIC	20.673	Loss
TK_Src_SrcA_SRC_Y	P35968	KDR	P12931	SRC	Y1309	S1307F	1307	Missense	proximal	-2	no	21.429	20.448	EPSD	COSMIC	20.673	Loss
TK_Src_SrcA_SRC_Y	P35968	KDR	P12931	SRC	Y1309	S1303G	1303	Missense	distal	-6	no	21.429	21.286	EPSD	COSMIC	20.673	Down-regulation
TK_Src_SrcA_SRC_Y	P35968	KDR	P12931	SRC	Y1319	D1313N	1313	Missense	distal	-6	no	21.524	21.334	EPSD	COSMIC	20.673	Down-regulation
TK_Src_SrcA_SRC_Y	P35968	KDR	P12931	SRC	Y1319	T1316P	1316	Missense	distal	-3	no	21.524	21.117	EPSD	COSMIC	20.673	Down-regulation
TK_Src_SrcA_SRC_Y	P35968	KDR	P12931	SRC	Y1319	V1318M	1318	Missense	proximal	-1	no	21.524	19.918	EPSD	COSMIC	20.673	Loss
TK_Src_SrcA_SRC_Y	P35968	KDR	P12931	SRC	Y1319	E1322A	1322	Missense	distal	3	no	21.524	21.609	EPSD	COSMIC	20.673	Up-regulation
TK_Src_SrcA_SRC_Y	P35968	KDR	P12931	SRC	Y1319	E1325K	1325	Missense	distal	6	no	21.524	21.522	EPSD	COSMIC	20.673	Down-regulation
TK_Src_SrcA_SRC_Y	P35968	KDR	P12931	SRC	Y1319	E1323K	1323	Missense	distal	4	no	21.524	21.525	EPSD	COSMIC	20.673	Up-regulation
TK_Src_SrcA_SRC_Y	P51813	BMX	P12931	SRC	Y40	T36K	36	Missense	distal	-4	no	21.486	21.157	EPSD	COSMIC	20.673	Down-regulation
TK_Src_SrcA_SRC_Y	P51813	BMX	P12931	SRC	Y40	L38F	38	Missense	proximal	-2	no	21.486	21.250	EPSD	COSMIC	20.673	Down-regulation
TK_Src_SrcA_SRC_Y	P51813	BMX	P12931	SRC	Y216	T211P	211	Missense	distal	-5	no	20.832	21.038	EPSD	COSMIC	20.673	Up-regulation
TK_Src_SrcA_SRC_Y	P51813	BMX	P12931	SRC	Y216	S220L	220	Missense	distal	4	no	20.832	20.839	EPSD	COSMIC	20.673	Up-regulation
TK_Src_SrcA_SRC_Y	P00519	ABL1	P12931	SRC	Y172	Y167H	167	Missense	distal	-5	no	20.011	20.677	EPSD	COSMIC	20.673	Gain
TK_Src_SrcA_SRC_Y	P00519	ABL1	P12931	SRC	Y185	R191C	191	Missense	distal	6	no	23.126	23.206	EPSD	COSMIC	20.673	Up-regulation
TK_Src_SrcA_SRC_Y	P00519	ABL1	P12931	SRC	Y185	S187F	187	Missense	proximal	2	no	23.126	21.706	EPSD	COSMIC	20.673	Down-regulation
TK_Src_SrcA_SRC_Y	P00519	ABL1	P12931	SRC	Y185	L184R	184	Missense	proximal	-1	no	23.126	21.473	EPSD	COSMIC	20.673	Down-regulation
TK_Src_SrcA_SRC_Y	P00519	ABL1	P12931	SRC	Y226	R220H	220	Missense	distal	-6	no	21.982	21.950	EPSD	COSMIC	20.673	Down-regulation
TK_Src_SrcA_SRC_Y	P00519	ABL1	P12931	SRC	Y226	N231S	231	Missense	distal	5	no	21.982	21.983	EPSD	COSMIC	20.673	Up-regulation
TK_Src_SrcA_SRC_Y	P00519	ABL1	P12931	SRC	Y226	G227S	227	Missense	proximal	1	no	21.982	21.868	EPSD	COSMIC	20.673	Down-regulation
TK_Src_SrcA_SRC_Y	P00519	ABL1	P12931	SRC	Y226	N231K	231	Missense	distal	5	no	21.982	22.065	EPSD	COSMIC	20.673	Up-regulation
TK_Src_SrcA_SRC_Y	P00519	ABL1	P12931	SRC	Y232	N231S	231	Missense	proximal	-1	no	20.142	21.078	EPSD	COSMIC	20.673	Gain
TK_Src_SrcA_SRC_Y	P00519	ABL1	P12931	SRC	Y232	W235L	235	Missense	distal	3	no	20.142	21.927	EPSD	COSMIC	20.673	Gain
TK_Src_SrcA_SRC_Y	P00519	ABL1	P12931	SRC	Y253	G250E	250	Missense	distal	-3	no	21.615	22.218	EPSD	COSMIC	20.673	Up-regulation
TK_Src_SrcA_SRC_Y	P00519	ABL1	P12931	SRC	Y253	E255K	255	Missense	proximal	2	no	21.615	20.445	EPSD	COSMIC	20.673	Loss
TK_Src_SrcA_SRC_Y	P00519	ABL1	P12931	SRC	Y253	Y253H	253	Missense	central	0	yes	21.615	0.000	EPSD	COSMIC	20.673	Loss
TK_Src_SrcA_SRC_Y	P00519	ABL1	P12931	SRC	Y253	Q252H	252	Missense	proximal	-1	no	21.615	21.678	EPSD	COSMIC	20.673	Up-regulation
TK_Src_SrcA_SRC_Y	P00519	ABL1	P12931	SRC	Y253	L248V	248	Missense	distal	-5	no	21.615	21.776	EPSD	COSMIC	20.673	Up-regulation
TK_Src_SrcA_SRC_Y	P00519	ABL1	P12931	SRC	Y253	Y253F	253	Missense	central	0	yes	21.615	0.000	EPSD	COSMIC	20.673	Loss
TK_Src_SrcA_SRC_Y	P00519	ABL1	P12931	SRC	Y253	E255V	255	Missense	proximal	2	no	21.615	21.646	EPSD	COSMIC	20.673	Up-regulation
TK_Src_SrcA_SRC_Y	P00519	ABL1	P12931	SRC	Y253	K247E	247	Missense	distal	-6	no	21.615	21.627	EPSD	COSMIC	20.673	Up-regulation
TK_Src_SrcA_SRC_Y	P00519	ABL1	P12931	SRC	Y253	Q252K	252	Missense	proximal	-1	no	21.615	20.112	EPSD	COSMIC	20.673	Loss
TK_Src_SrcA_SRC_Y	P00519	ABL1	P12931	SRC	Y253	Y257C	257	Missense	distal	4	no	21.615	21.624	EPSD	COSMIC;CCLE	20.673	Up-regulation
TK_Src_SrcA_SRC_Y	P00519	ABL1	P12931	SRC	Y253	E255L	255	Missense	proximal	2	no	21.615	20.724	EPSD	COSMIC	20.673	Down-regulation
TK_Src_SrcA_SRC_Y	P00519	ABL1	P12931	SRC	Y253	G254E	254	Missense	proximal	1	no	21.615	22.598	EPSD	COSMIC	20.673	Up-regulation
TK_Src_SrcA_SRC_Y	P00519	ABL1	P12931	SRC	Y253	Q252M	252	Missense	proximal	-1	no	21.615	20.939	EPSD	COSMIC	20.673	Down-regulation
TK_Src_SrcA_SRC_Y	P00519	ABL1	P12931	SRC	Y253	G251E	251	Missense	proximal	-2	no	21.615	22.192	EPSD	COSMIC	20.673	Up-regulation
TK_Src_SrcA_SRC_Y	P00519	ABL1	P12931	SRC	Y253	Q252E	252	Missense	proximal	-1	no	21.615	22.020	EPSD	COSMIC	20.673	Up-regulation
TK_Src_SrcA_SRC_Y	P00519	ABL1	P12931	SRC	Y253	K247R	247	Missense	distal	-6	no	21.615	21.400	EPSD	COSMIC	20.673	Down-regulation
TK_Src_SrcA_SRC_Y	P00519	ABL1	P12931	SRC	Y253	G251D	251	Missense	proximal	-2	no	21.615	21.905	EPSD	COSMIC	20.673	Up-regulation
TK_Src_SrcA_SRC_Y	P00519	ABL1	P12931	SRC	Y253	Q252R	252	Missense	proximal	-1	no	21.615	19.782	EPSD	COSMIC	20.673	Loss
TK_Src_SrcA_SRC_Y	P00519	ABL1	P12931	SRC	Y253	Q252P	252	Missense	proximal	-1	no	21.615	21.448	EPSD	COSMIC	20.673	Down-regulation
TK_Src_SrcA_SRC_Y	P00519	ABL1	P12931	SRC	Y253	V256L	256	Missense	distal	3	no	21.615	21.642	EPSD	COSMIC	20.673	Up-regulation
TK_Src_SrcA_SRC_Y	P00519	ABL1	P12931	SRC	Y253	G251C	251	Missense	proximal	-2	no	21.615	19.761	EPSD	COSMIC	20.673	Loss
TK_Src_SrcA_SRC_Y	P00519	ABL1	P12931	SRC	Y253	E255D	255	Missense	proximal	2	no	21.615	21.327	EPSD	COSMIC	20.673	Down-regulation
TK_Src_SrcA_SRC_Y	P00519	ABL1	P12931	SRC	Y253	E258A	258	Missense	distal	5	no	21.615	21.521	EPSD	COSMIC	20.673	Down-regulation
TK_Src_SrcA_SRC_Y	P00519	ABL1	P12931	SRC	Y253	Y253C	253	Missense	central	0	yes	21.615	0.000	EPSD	COSMIC;CCLE	20.673	Loss
TK_Src_SrcA_SRC_Y	P00519	ABL1	P12931	SRC	Y253	E258V	258	Missense	distal	5	no	21.615	21.662	EPSD	COSMIC	20.673	Up-regulation
TK_Src_SrcA_SRC_Y	P00519	ABL1	P12931	SRC	Y253	H246D	246	Missense	distal	-7	no	21.615	21.710	EPSD	COSMIC	20.673	Up-regulation
TK_Src_SrcA_SRC_Y	P00519	ABL1	P12931	SRC	Y253	H246R	246	Missense	distal	-7	no	21.615	21.909	EPSD	COSMIC	20.673	Up-regulation
TK_Src_SrcA_SRC_Y	P00519	ABL1	P12931	SRC	Y253	L248R	248	Missense	distal	-5	no	21.615	21.789	EPSD	COSMIC	20.673	Up-regulation
TK_Src_SrcA_SRC_Y	P00519	ABL1	P12931	SRC	Y253	V260A	260	Missense	distal	7	no	21.615	21.538	EPSD	COSMIC	20.673	Down-regulation
TK_Src_SrcA_SRC_Y	P00519	ABL1	P12931	SRC	Y257	G250E	250	Missense	distal	-7	no	22.586	23.037	EPSD	COSMIC	20.673	Up-regulation
TK_Src_SrcA_SRC_Y	P00519	ABL1	P12931	SRC	Y257	E255K	255	Missense	proximal	-2	no	22.586	21.227	EPSD	COSMIC	20.673	Down-regulation
TK_Src_SrcA_SRC_Y	P00519	ABL1	P12931	SRC	Y257	Y253H	253	Missense	distal	-4	no	22.586	22.419	EPSD	COSMIC	20.673	Down-regulation
TK_Src_SrcA_SRC_Y	P00519	ABL1	P12931	SRC	Y257	Q252H	252	Missense	distal	-5	no	22.586	22.955	EPSD	COSMIC	20.673	Up-regulation
TK_Src_SrcA_SRC_Y	P00519	ABL1	P12931	SRC	Y257	Y253F	253	Missense	distal	-4	no	22.586	21.714	EPSD	COSMIC	20.673	Down-regulation
TK_Src_SrcA_SRC_Y	P00519	ABL1	P12931	SRC	Y257	K263N	263	Missense	distal	6	no	22.586	22.542	EPSD	COSMIC	20.673	Down-regulation
TK_Src_SrcA_SRC_Y	P00519	ABL1	P12931	SRC	Y257	E255V	255	Missense	proximal	-2	no	22.586	20.732	EPSD	COSMIC	20.673	Down-regulation
TK_Src_SrcA_SRC_Y	P00519	ABL1	P12931	SRC	Y257	Y264C	264	Missense	distal	7	no	22.586	22.710	EPSD	COSMIC	20.673	Up-regulation
TK_Src_SrcA_SRC_Y	P00519	ABL1	P12931	SRC	Y257	Q252K	252	Missense	distal	-5	no	22.586	22.437	EPSD	COSMIC	20.673	Down-regulation
TK_Src_SrcA_SRC_Y	P00519	ABL1	P12931	SRC	Y257	Y257C	257	Missense	central	0	yes	22.586	0.000	EPSD	COSMIC;CCLE	20.673	Loss
TK_Src_SrcA_SRC_Y	P00519	ABL1	P12931	SRC	Y257	E255L	255	Missense	proximal	-2	no	22.586	20.652	EPSD	COSMIC	20.673	Loss
TK_Src_SrcA_SRC_Y	P00519	ABL1	P12931	SRC	Y257	G254E	254	Missense	distal	-3	no	22.586	23.189	EPSD	COSMIC	20.673	Up-regulation
TK_Src_SrcA_SRC_Y	P00519	ABL1	P12931	SRC	Y257	Q252M	252	Missense	distal	-5	no	22.586	22.413	EPSD	COSMIC	20.673	Down-regulation
TK_Src_SrcA_SRC_Y	P00519	ABL1	P12931	SRC	Y257	G251E	251	Missense	distal	-6	no	22.586	22.815	EPSD	COSMIC	20.673	Up-regulation
TK_Src_SrcA_SRC_Y	P00519	ABL1	P12931	SRC	Y257	Q252E	252	Missense	distal	-5	no	22.586	23.013	EPSD	COSMIC	20.673	Up-regulation
TK_Src_SrcA_SRC_Y	P00519	ABL1	P12931	SRC	Y257	G251D	251	Missense	distal	-6	no	22.586	22.893	EPSD	COSMIC	20.673	Up-regulation
TK_Src_SrcA_SRC_Y	P00519	ABL1	P12931	SRC	Y257	Q252R	252	Missense	distal	-5	no	22.586	22.745	EPSD	COSMIC	20.673	Up-regulation
TK_Src_SrcA_SRC_Y	P00519	ABL1	P12931	SRC	Y257	Q252P	252	Missense	distal	-5	no	22.586	22.727	EPSD	COSMIC	20.673	Up-regulation
TK_Src_SrcA_SRC_Y	P00519	ABL1	P12931	SRC	Y257	V256L	256	Missense	proximal	-1	no	22.586	21.476	EPSD	COSMIC	20.673	Down-regulation
TK_Src_SrcA_SRC_Y	P00519	ABL1	P12931	SRC	Y257	G251C	251	Missense	distal	-6	no	22.586	22.192	EPSD	COSMIC	20.673	Down-regulation
TK_Src_SrcA_SRC_Y	P00519	ABL1	P12931	SRC	Y257	E255D	255	Missense	proximal	-2	no	22.586	22.299	EPSD	COSMIC	20.673	Down-regulation
TK_Src_SrcA_SRC_Y	P00519	ABL1	P12931	SRC	Y257	E258A	258	Missense	proximal	1	no	22.586	21.289	EPSD	COSMIC	20.673	Down-regulation
TK_Src_SrcA_SRC_Y	P00519	ABL1	P12931	SRC	Y257	Y253C	253	Missense	distal	-4	no	22.586	21.303	EPSD	COSMIC;CCLE	20.673	Down-regulation
TK_Src_SrcA_SRC_Y	P00519	ABL1	P12931	SRC	Y257	E258V	258	Missense	proximal	1	no	22.586	20.704	EPSD	COSMIC	20.673	Down-regulation
TK_Src_SrcA_SRC_Y	P00519	ABL1	P12931	SRC	Y257	Y264N	264	Missense	distal	7	no	22.586	22.567	EPSD	COSMIC	20.673	Down-regulation
TK_Src_SrcA_SRC_Y	P00519	ABL1	P12931	SRC	Y257	V260A	260	Missense	distal	3	no	22.586	22.016	EPSD	COSMIC	20.673	Down-regulation
TK_Src_SrcA_SRC_Y	P00519	ABL1	P12931	SRC	Y393	R386Q	386	Missense	distal	-7	no	24.701	24.477	EPSD	COSMIC	20.673	Down-regulation
TK_Src_SrcA_SRC_Y	P00519	ABL1	P12931	SRC	Y393	A397P	397	Missense	distal	4	no	24.701	24.682	EPSD	COSMIC	20.673	Down-regulation
TK_Src_SrcA_SRC_Y	P00519	ABL1	P12931	SRC	Y393	H396R	396	Missense	distal	3	no	24.701	23.512	EPSD	COSMIC	20.673	Down-regulation
TK_Src_SrcA_SRC_Y	P00519	ABL1	P12931	SRC	Y393	L387M	387	Missense	distal	-6	no	24.701	24.230	EPSD	COSMIC	20.673	Down-regulation
TK_Src_SrcA_SRC_Y	P00519	ABL1	P12931	SRC	Y393	M388L	388	Missense	distal	-5	no	24.701	24.859	EPSD	COSMIC	20.673	Up-regulation
TK_Src_SrcA_SRC_Y	P00519	ABL1	P12931	SRC	Y393	G398R	398	Missense	distal	5	no	24.701	24.520	EPSD	COSMIC	20.673	Down-regulation
TK_Src_SrcA_SRC_Y	P00519	ABL1	P12931	SRC	Y393	A399T	399	Missense	distal	6	no	24.701	24.688	EPSD	COSMIC	20.673	Down-regulation
TK_Src_SrcA_SRC_Y	P00519	ABL1	P12931	SRC	Y393	T389A	389	Missense	distal	-4	no	24.701	24.427	EPSD	COSMIC	20.673	Down-regulation
TK_Src_SrcA_SRC_Y	P00519	ABL1	P12931	SRC	Y393	K400E	400	Missense	distal	7	no	24.701	24.697	EPSD	COSMIC	20.673	Down-regulation
TK_Src_SrcA_SRC_Y	P00519	ABL1	P12931	SRC	Y393	T394A	394	Missense	proximal	1	no	24.701	25.156	EPSD	COSMIC	20.673	Up-regulation
TK_Src_SrcA_SRC_Y	P00519	ABL1	P12931	SRC	Y393	H396P	396	Missense	distal	3	no	24.701	25.298	EPSD	COSMIC	20.673	Up-regulation
TK_Src_SrcA_SRC_Y	P00519	ABL1	P12931	SRC	Y393	D391N	391	Missense	proximal	-2	no	24.701	24.421	EPSD	COSMIC	20.673	Down-regulation
TK_Src_SrcA_SRC_Y	P00519	ABL1	P12931	SRC	Y393	L387F	387	Missense	distal	-6	no	24.701	24.634	EPSD	COSMIC	20.673	Down-regulation
TK_Src_SrcA_SRC_Y	P00519	ABL1	P12931	SRC	Y393	H396Y	396	Missense	distal	3	no	24.701	24.799	EPSD	COSMIC	20.673	Up-regulation
TK_Src_SrcA_SRC_Y	P00519	ABL1	P12931	SRC	Y393	G390W	390	Missense	distal	-3	no	24.701	22.598	EPSD	COSMIC	20.673	Down-regulation
TK_Src_SrcA_SRC_Y	P00519	ABL1	P12931	SRC	Y413	L411P	411	Missense	proximal	-2	no	19.798	21.329	EPSD	COSMIC	20.673	Gain
TK_Src_SrcA_SRC_Y	P00519	ABL1	P12931	SRC	Y469	R473Q	473	Missense	distal	4	no	22.763	22.784	EPSD	COSMIC	20.673	Up-regulation
TK_Src_SrcA_SRC_Y	P00519	ABL1	P12931	SRC	Y469	E466D	466	Missense	distal	-3	no	22.763	22.808	EPSD	COSMIC	20.673	Up-regulation
TK_Src_SrcA_SRC_Y	P00519	ABL1	P12931	SRC	Y469	M472L	472	Missense	distal	3	no	22.763	23.156	EPSD	COSMIC	20.673	Up-regulation
TK_Src_SrcA_SRC_Y	P14923	JUP	P12931	SRC	Y22	S28L	28	Missense	distal	6	no	21.760	21.791	EPSD	COSMIC;GDSC;CCLE	20.673	Up-regulation
TK_Src_SrcA_SRC_Y	P14923	JUP	P12931	SRC	Y74	P67S	67	Missense	distal	-7	no	21.511	21.632	EPSD	COSMIC	20.673	Up-regulation
TK_Src_SrcA_SRC_Y	P14923	JUP	P12931	SRC	Y324	L327M	327	Missense	distal	3	no	23.020	22.627	EPSD	COSMIC	20.673	Down-regulation
TK_Src_SrcA_SRC_Y	P14923	JUP	P12931	SRC	Y644	N638H	638	Missense	distal	-6	no	20.870	20.724	PhosphoSitePlus	COSMIC;GDSC;CCLE	20.673	Down-regulation
TK_Src_SrcA_SRC_Y	Q8WWM7	ATXN2L	P12931	SRC	Y118	G116C	116	Missense	proximal	-2	no	21.721	19.868	EPSD	COSMIC	20.673	Loss
TK_Src_SrcA_SRC_Y	Q8WWM7	ATXN2L	P12931	SRC	Y118	R122K	122	Missense	distal	4	no	21.721	21.736	EPSD	COSMIC	20.673	Up-regulation
TK_Src_SrcA_SRC_Y	Q8WWM7	ATXN2L	P12931	SRC	Y118	N120H	120	Missense	proximal	2	no	21.721	20.985	EPSD	COSMIC	20.673	Down-regulation
TK_Src_SrcA_SRC_Y	Q8WWM7	ATXN2L	P12931	SRC	Y241	D239N	239	Missense	proximal	-2	no	21.503	21.223	EPSD	COSMIC	20.673	Down-regulation
TK_Src_SrcA_SRC_Y	Q8WWM7	ATXN2L	P12931	SRC	Y241	D246Y	246	Missense	distal	5	no	21.503	22.075	EPSD	COSMIC	20.673	Up-regulation
TK_Src_SrcA_SRC_Y	Q13017	ARHGAP5	P12931	SRC	Y306	H300R	300	Missense	distal	-6	no	21.741	21.774	EPSD	COSMIC	20.673	Up-regulation
TK_Src_SrcA_SRC_Y	Q13017	ARHGAP5	P12931	SRC	Y306	P301L	301	Missense	distal	-5	no	21.741	21.585	EPSD	COSMIC;GDSC;CCLE	20.673	Down-regulation
TK_Src_SrcA_SRC_Y	Q13017	ARHGAP5	P12931	SRC	Y306	G311R	311	Missense	distal	5	no	21.741	21.560	EPSD	COSMIC	20.673	Down-regulation
TK_Src_SrcA_SRC_Y	Q13017	ARHGAP5	P12931	SRC	Y630	D633V	633	Missense	distal	3	no	24.121	24.871	EPSD	COSMIC	20.673	Up-regulation
TK_Src_SrcA_SRC_Y	Q13017	ARHGAP5	P12931	SRC	Y991	P993S	993	Missense	proximal	2	no	21.393	22.000	EPSD	COSMIC	20.673	Up-regulation
TK_Src_SrcA_SRC_Y	Q13017	ARHGAP5	P12931	SRC	Y1091	D1084Y	1084	Missense	distal	-7	no	21.295	20.845	EPSD	COSMIC	20.673	Down-regulation
TK_Src_SrcA_SRC_Y	Q13017	ARHGAP5	P12931	SRC	Y1296	C1291Y	1291	Missense	distal	-5	no	20.607	20.871	EPSD	COSMIC;GDSC;CCLE	20.673	Gain
TK_Src_SrcA_SRC_Y	P49023	PXN	P12931	SRC	Y31	P30L	30	Missense	proximal	-1	no	23.146	23.132	EPSD	COSMIC	20.673	Down-regulation
TK_Src_SrcA_SRC_Y	P49023	PXN	P12931	SRC	Y88	S83N	83	Missense	distal	-5	no	24.784	24.656	PhosphoSitePlus	COSMIC	20.673	Down-regulation
TK_Src_SrcA_SRC_Y	P49023	PXN	P12931	SRC	Y118	F120S	120	Missense	proximal	2	no	23.383	24.803	EPSD	COSMIC	20.673	Up-regulation
TK_Src_SrcA_SRC_Y	P49023	PXN	P12931	SRC	Y181	G175W	175	Missense	distal	-6	no	22.194	21.929	EPSD	COSMIC	20.673	Down-regulation
TK_Src_SrcA_SRC_Y	P12956	XRCC6	P12931	SRC	Y30	G28E	28	Missense	proximal	-2	no	20.295	20.872	EPSD	COSMIC;GDSC	20.673	Gain
TK_Src_SrcA_SRC_Y	P12956	XRCC6	P12931	SRC	Y322	I328V	328	Missense	distal	6	no	21.247	21.241	EPSD	COSMIC	20.673	Down-regulation
TK_Src_SrcA_SRC_Y	P12956	XRCC6	P12931	SRC	Y322	R325C	325	Missense	distal	3	no	21.247	21.459	EPSD	COSMIC;GDSC;CCLE	20.673	Up-regulation
TK_Src_SrcA_SRC_Y	P12956	XRCC6	P12931	SRC	Y530	P531S	531	Missense	proximal	1	no	19.640	21.785	PhosphoSitePlus	COSMIC;GDSC;CCLE	20.673	Gain
TK_Src_SrcA_SRC_Y	Q6UN15	FIP1L1	P12931	SRC	Y27	E22G	22	Missense	distal	-5	no	21.068	20.815	EPSD	COSMIC	20.673	Down-regulation
TK_Src_SrcA_SRC_Y	Q6UN15	FIP1L1	P12931	SRC	Y110	G111E	111	Missense	proximal	1	no	21.781	22.765	PhosphoSitePlus	COSMIC	20.673	Up-regulation
TK_Src_SrcA_SRC_Y	Q6UN15	FIP1L1	P12931	SRC	Y129	G133E	133	Missense	distal	4	no	21.466	21.478	EPSD	COSMIC;GDSC	20.673	Up-regulation
TK_Src_SrcA_SRC_Y	Q6UN15	FIP1L1	P12931	SRC	Y426	R419H	419	Missense	distal	-7	no	21.351	21.056	EPSD	COSMIC;CCLE	20.673	Down-regulation
TK_Src_SrcA_SRC_Y	P08559	PDHA1	P12931	SRC	Y227	R226H	226	Missense	proximal	-1	no	19.325	21.221	EPSD	COSMIC	20.673	Gain
TK_Src_SrcA_SRC_Y	P08559	PDHA1	P12931	SRC	Y369	D372G	372	Missense	distal	3	no	20.573	20.946	EPSD	COSMIC	20.673	Gain
TK_Src_SrcA_SRC_Y	P08559	PDHA1	P12931	SRC	Y369	D372N	372	Missense	distal	3	no	20.573	21.649	EPSD	COSMIC	20.673	Gain
TK_Src_SrcA_SRC_Y	P08727	KRT19	P12931	SRC	Y130	S124P	124	Missense	distal	-6	no	23.627	23.578	EPSD	COSMIC;GDSC	20.673	Down-regulation
TK_Src_SrcA_SRC_Y	P08727	KRT19	P12931	SRC	Y131	S124P	124	Missense	distal	-7	no	23.221	23.100	EPSD	COSMIC;GDSC	20.673	Down-regulation
TK_Src_SrcA_SRC_Y	P08727	KRT19	P12931	SRC	Y256	R253Q	253	Missense	distal	-3	no	20.885	21.501	EPSD	COSMIC	20.673	Up-regulation
TK_Src_SrcA_SRC_Y	Q14721	KCNB1	P12931	SRC	Y128	E126K	126	Missense	proximal	-2	no	21.700	20.341	PhosphoSitePlus	COSMIC	20.673	Loss
TK_Src_SrcA_SRC_Y	Q14721	KCNB1	P12931	SRC	Y128	Y128N	128	Missense	central	0	yes	21.700	0.000	PhosphoSitePlus	COSMIC	20.673	Loss
TK_Src_SrcA_SRC_Y	O15259	NPHP1	P12931	SRC	Y46	L52S	52	Missense	distal	6	no	21.083	21.051	EPSD	COSMIC	20.673	Down-regulation
TK_Src_SrcA_SRC_Y	Q9UN19	DAPP1	P12931	SRC	Y139	S137F	137	Missense	proximal	-2	no	23.548	22.568	PhosphoSitePlus	COSMIC	20.673	Down-regulation
TK_Src_SrcA_SRC_Y	P11511	CYP19A1	P12931	SRC	Y184	E177K	177	Missense	distal	-7	no	23.226	23.063	EPSD	COSMIC	20.673	Down-regulation
TK_Src_SrcA_SRC_Y	P11511	CYP19A1	P12931	SRC	Y184	V187M	187	Missense	distal	3	no	23.226	22.860	EPSD	COSMIC	20.673	Down-regulation
TK_Src_SrcA_SRC_Y	P11511	CYP19A1	P12931	SRC	Y361	R365Q	365	Missense	distal	4	no	22.879	22.901	PhosphoSitePlus	COSMIC	20.673	Up-regulation
TK_Src_SrcA_SRC_Y	P98161	PKD1	P12931	SRC	Y4237	E4240K	4240	Missense	distal	3	no	23.643	22.305	PhosphoSitePlus	COSMIC	20.673	Down-regulation
TK_Src_SrcA_SRC_Y	P98161	PKD1	P12931	SRC	Y4237	H4244Y	4244	Missense	distal	7	no	23.643	23.605	PhosphoSitePlus	COSMIC	20.673	Down-regulation
TK_Src_SrcA_SRC_Y	P98161	PKD1	P12931	SRC	Y4237	T4233S	4233	Missense	distal	-4	no	23.643	23.763	PhosphoSitePlus	COSMIC	20.673	Up-regulation
TK_Src_SrcA_SRC_Y	Q9UK17	KCND3	P12931	SRC	Y108	R107H	107	Missense	proximal	-1	no	18.809	20.705	PhosphoSitePlus	COSMIC	20.673	Gain
TK_Src_SrcA_SRC_Y	P10636	MAPT	P12931	SRC	Y18	R23K	23	Missense	distal	5	no	21.842	21.899	PhosphoSitePlus	COSMIC	20.673	Up-regulation
TK_Src_SrcA_SRC_Y	P10636	MAPT	P12931	SRC	Y29	T30S	30	Missense	proximal	1	no	20.502	21.156	EPSD	COSMIC	20.673	Gain
TK_Src_SrcA_SRC_Y	P10636	MAPT	P12931	SRC	Y29	R23K	23	Missense	distal	-6	no	20.502	20.716	EPSD	COSMIC	20.673	Gain
TK_Src_SrcA_SRC_Y	P10636	MAPT	P12931	SRC	Y514	G521V	521	Missense	distal	7	no	21.389	21.423	EPSD	COSMIC	20.673	Up-regulation
TK_Src_SrcA_SRC_Y	P10636	MAPT	P12931	SRC	Y514	G518V	518	Missense	distal	4	no	21.389	21.385	EPSD	COSMIC	20.673	Down-regulation
TK_Src_SrcA_SRC_Y	P10636	MAPT	P12931	SRC	Y514	R511C	511	Missense	distal	-3	no	21.389	19.741	EPSD	COSMIC;CCLE	20.673	Loss
TK_Src_SrcA_SRC_Y	P10636	MAPT	P12931	SRC	Y514	G509V	509	Missense	distal	-5	no	21.389	21.360	EPSD	COSMIC	20.673	Down-regulation
TK_Src_SrcA_SRC_Y	P10636	MAPT	P12931	SRC	Y711	E708D	708	Missense	distal	-3	no	22.032	22.077	EPSD	COSMIC	20.673	Up-regulation
TK_Src_SrcA_SRC_Y	P10636	MAPT	P12931	SRC	Y711	G706R	706	Missense	distal	-5	no	22.032	22.017	EPSD	COSMIC	20.673	Down-regulation
TK_Src_SrcA_SRC_Y	P10636	MAPT	P12931	SRC	Y711	V710M	710	Missense	proximal	-1	no	22.032	20.426	EPSD	COSMIC	20.673	Loss
TK_Src_SrcA_SRC_Y	P10636	MAPT	P12931	SRC	Y711	E708K	708	Missense	distal	-3	no	22.032	20.321	EPSD	COSMIC	20.673	Loss
TK_Src_SrcA_SRC_Y	P10636	MAPT	P12931	SRC	Y711	V710A	710	Missense	proximal	-1	no	22.032	20.695	EPSD	COSMIC	20.673	Down-regulation
TK_Src_SrcA_SRC_Y	P78352	DLG4	P12931	SRC	Y397	P394A	394	Missense	distal	-3	no	21.654	21.866	EPSD	COSMIC	20.673	Up-regulation
TK_Src_SrcA_SRC_Y	P78352	DLG4	P12931	SRC	Y523	R516Q	516	Missense	distal	-7	no	20.976	20.751	PhosphoSitePlus	COSMIC	20.673	Down-regulation
TK_Src_SrcA_SRC_Y	P78352	DLG4	P12931	SRC	Y523	M529I	529	Missense	distal	6	no	20.976	20.954	PhosphoSitePlus	COSMIC	20.673	Down-regulation
TK_Src_SrcA_SRC_Y	P78352	DLG4	P12931	SRC	Y523	T527M	527	Missense	distal	4	no	20.976	20.917	PhosphoSitePlus	COSMIC	20.673	Down-regulation
TK_Src_SrcA_SRC_Y	P78352	DLG4	P12931	SRC	Y523	S519W	519	Missense	distal	-4	no	20.976	19.873	PhosphoSitePlus	COSMIC	20.673	Loss
TK_Src_SrcA_SRC_Y	P78352	DLG4	P12931	SRC	Y523	E524D	524	Missense	proximal	1	no	20.976	20.370	PhosphoSitePlus	COSMIC	20.673	Loss
TK_Src_SrcA_SRC_Y	P78352	DLG4	P12931	SRC	Y604	F598L	598	Missense	distal	-6	no	21.886	21.954	EPSD	COSMIC	20.673	Up-regulation
TK_Src_SrcA_SRC_Y	P42224	STAT1	P12931	SRC	Y68	E74K	74	Missense	distal	6	no	22.217	22.215	EPSD	COSMIC	20.673	Down-regulation
TK_Src_SrcA_SRC_Y	Q9NR80	ARHGEF4	P12931	SRC	Y165	S160R	160	Missense	distal	-5	no	23.635	23.551	EPSD	COSMIC	20.673	Down-regulation
TK_Src_SrcA_SRC_Y	Q9NR80	ARHGEF4	P12931	SRC	Y165	D167Y	167	Missense	proximal	2	no	23.635	23.655	EPSD	COSMIC	20.673	Up-regulation
TK_Src_SrcA_SRC_Y	Q9NR80	ARHGEF4	P12931	SRC	Y175	G179L	179	Missense	distal	4	no	22.527	22.559	EPSD	COSMIC	20.673	Up-regulation
TK_Src_SrcA_SRC_Y	P50281	MMP14	P12931	SRC	Y138	V135M	135	Missense	distal	-3	no	22.285	21.802	EPSD	COSMIC	20.673	Down-regulation
TK_Src_SrcA_SRC_Y	P50281	MMP14	P12931	SRC	Y138	K134N	134	Missense	distal	-4	no	22.285	23.148	EPSD	COSMIC	20.673	Up-regulation
TK_Src_SrcA_SRC_Y	O43613	HCRTR1	P12931	SRC	Y27	P20L	20	Missense	distal	-7	no	21.876	21.761	EPSD	COSMIC	20.673	Down-regulation
CMGC_CDK_CDK2_CDK3_ST	Q5TKA1	LIN9	Q00526	CDK3	T304	S309Y	309	Missense	distal	5	no	6.454	6.714	EPSD	COSMIC	5.767	Up-regulation
CMGC_CDK_CDK2_CDK3_ST	Q5TKA1	LIN9	Q00526	CDK3	S309	S309Y	309	Missense	central	0	yes	7.170	0.000	EPSD	COSMIC	5.767	Loss
CMGC_CDK_CDK2_CDK3_ST	Q14934	NFATC4	Q00526	CDK3	S73	P75H	75	Missense	proximal	2	no	9.406	9.721	EPSD	COSMIC	5.767	Up-regulation
CMGC_CDK_CDK2_CDK3_ST	Q14934	NFATC4	Q00526	CDK3	S73	P66H	66	Missense	distal	-7	no	9.406	9.718	EPSD	COSMIC	5.767	Up-regulation
CMGC_CDK_CDK2_CDK3_ST	Q14934	NFATC4	Q00526	CDK3	S73	P66A	66	Missense	distal	-7	no	9.406	9.653	EPSD	COSMIC	5.767	Up-regulation
CMGC_CDK_CDK2_CDK3_ST	Q14934	NFATC4	Q00526	CDK3	S73	P69L	69	Missense	distal	-4	no	9.406	8.756	EPSD	COSMIC	5.767	Down-regulation
CMGC_CDK_CDK2_CDK3_ST	Q14934	NFATC4	Q00526	CDK3	S73	R77Q	77	Missense	distal	4	no	9.406	9.547	EPSD	COSMIC	5.767	Up-regulation
CMGC_CDK_CDK2_CDK3_ST	Q14934	NFATC4	Q00526	CDK3	S73	P78A	78	Missense	distal	5	no	9.406	9.454	EPSD	COSMIC	5.767	Up-regulation
CMGC_CDK_CDK2_CDK3_ST	Q14934	NFATC4	Q00526	CDK3	S73	S73L	73	Missense	central	0	yes	9.406	0.000	EPSD	COSMIC	5.767	Loss
CMGC_CDK_CDK2_CDK3_ST	Q14934	NFATC4	Q00526	CDK3	S120	P125H	125	Missense	distal	5	no	7.684	7.955	EPSD	COSMIC	5.767	Up-regulation
CMGC_CDK_CDK2_CDK3_ST	Q14934	NFATC4	Q00526	CDK3	S120	S122C	122	Missense	proximal	2	no	7.684	7.413	EPSD	COSMIC	5.767	Down-regulation
CMGC_CDK_CDK2_CDK3_ST	Q14934	NFATC4	Q00526	CDK3	S120	S120Y	120	Missense	central	0	yes	7.684	0.000	EPSD	COSMIC	5.767	Loss
CMGC_CDK_CDK2_CDK3_ST	Q14934	NFATC4	Q00526	CDK3	S120	P123S	123	Missense	distal	3	no	7.684	5.522	EPSD	COSMIC	5.767	Loss
CMGC_CDK_CDK2_CDK3_ST	Q14934	NFATC4	Q00526	CDK3	S120	P125Q	125	Missense	distal	5	no	7.684	7.878	EPSD	COSMIC	5.767	Up-regulation
CMGC_CDK_CDK2_CDK3_ST	Q14934	NFATC4	Q00526	CDK3	S120	P127L	127	Missense	distal	7	no	7.684	7.758	EPSD	COSMIC	5.767	Up-regulation
CMGC_CDK_CDK2_CDK3_ST	Q14934	NFATC4	Q00526	CDK3	S120	T124M	124	Missense	distal	4	no	7.684	7.660	EPSD	COSMIC	5.767	Down-regulation
CMGC_CDK_CDK2_CDK3_ST	Q14934	NFATC4	Q00526	CDK3	S122	P125H	125	Missense	distal	3	no	7.523	5.385	EPSD	COSMIC	5.767	Loss
CMGC_CDK_CDK2_CDK3_ST	Q14934	NFATC4	Q00526	CDK3	S122	P128S	128	Missense	distal	6	no	7.523	7.487	EPSD	COSMIC	5.767	Down-regulation
CMGC_CDK_CDK2_CDK3_ST	Q14934	NFATC4	Q00526	CDK3	S122	S122C	122	Missense	central	0	yes	7.523	0.000	EPSD	COSMIC	5.767	Loss
CMGC_CDK_CDK2_CDK3_ST	Q14934	NFATC4	Q00526	CDK3	S122	S120Y	120	Missense	proximal	-2	no	7.523	7.790	EPSD	COSMIC	5.767	Up-regulation
CMGC_CDK_CDK2_CDK3_ST	Q14934	NFATC4	Q00526	CDK3	S122	P123S	123	Missense	proximal	1	no	7.523	2.459	EPSD	COSMIC	5.767	Loss
CMGC_CDK_CDK2_CDK3_ST	Q14934	NFATC4	Q00526	CDK3	S122	P125Q	125	Missense	distal	3	no	7.523	5.295	EPSD	COSMIC	5.767	Loss
CMGC_CDK_CDK2_CDK3_ST	Q14934	NFATC4	Q00526	CDK3	S122	P127L	127	Missense	distal	5	no	7.523	7.863	EPSD	COSMIC	5.767	Up-regulation
CMGC_CDK_CDK2_CDK3_ST	Q14934	NFATC4	Q00526	CDK3	S122	T124M	124	Missense	proximal	2	no	7.523	7.416	EPSD	COSMIC	5.767	Down-regulation
CMGC_CDK_CDK2_CDK3_ST	Q14934	NFATC4	Q00526	CDK3	T124	P125H	125	Missense	proximal	1	no	10.463	4.366	EPSD	COSMIC	5.767	Loss
CMGC_CDK_CDK2_CDK3_ST	Q14934	NFATC4	Q00526	CDK3	T124	P128S	128	Missense	distal	4	no	10.463	10.558	EPSD	COSMIC	5.767	Up-regulation
CMGC_CDK_CDK2_CDK3_ST	Q14934	NFATC4	Q00526	CDK3	T124	S122C	122	Missense	proximal	-2	no	10.463	10.781	EPSD	COSMIC	5.767	Up-regulation
CMGC_CDK_CDK2_CDK3_ST	Q14934	NFATC4	Q00526	CDK3	T124	S120Y	120	Missense	distal	-4	no	10.463	9.271	EPSD	COSMIC	5.767	Down-regulation
CMGC_CDK_CDK2_CDK3_ST	Q14934	NFATC4	Q00526	CDK3	T124	P123S	123	Missense	proximal	-1	no	10.463	10.459	EPSD	COSMIC	5.767	Down-regulation
CMGC_CDK_CDK2_CDK3_ST	Q14934	NFATC4	Q00526	CDK3	T124	P125Q	125	Missense	proximal	1	no	10.463	4.577	EPSD	COSMIC	5.767	Loss
CMGC_CDK_CDK2_CDK3_ST	Q14934	NFATC4	Q00526	CDK3	T124	P127L	127	Missense	distal	3	no	10.463	8.265	EPSD	COSMIC	5.767	Down-regulation
CMGC_CDK_CDK2_CDK3_ST	Q14934	NFATC4	Q00526	CDK3	T124	A130V	130	Missense	distal	6	no	10.463	10.446	EPSD	COSMIC	5.767	Down-regulation
CMGC_CDK_CDK2_CDK3_ST	Q14934	NFATC4	Q00526	CDK3	T124	T124M	124	Missense	central	0	yes	10.463	0.000	EPSD	COSMIC	5.767	Loss
CMGC_CDK_CDK2_CDK3_ST	Q14934	NFATC4	Q00526	CDK3	S142	P148S	148	Missense	distal	6	no	10.030	9.994	EPSD	COSMIC	5.767	Down-regulation
CMGC_CDK_CDK2_CDK3_ST	Q14934	NFATC4	Q00526	CDK3	S142	G141W	141	Missense	proximal	-1	no	10.030	10.031	EPSD	COSMIC	5.767	Up-regulation
CMGC_CDK_CDK2_CDK3_ST	Q14934	NFATC4	Q00526	CDK3	S142	R144I	144	Missense	proximal	2	no	10.030	9.754	EPSD	COSMIC	5.767	Down-regulation
CMGC_CDK_CDK2_CDK3_ST	Q14934	NFATC4	Q00526	CDK3	S142	P149Q	149	Missense	distal	7	no	10.030	10.090	EPSD	COSMIC	5.767	Up-regulation
CMGC_CDK_CDK2_CDK3_ST	Q14934	NFATC4	Q00526	CDK3	S142	R144K	144	Missense	proximal	2	no	10.030	9.947	EPSD	COSMIC	5.767	Down-regulation
CMGC_CDK_CDK2_CDK3_ST	Q14934	NFATC4	Q00526	CDK3	S142	W138L	138	Missense	distal	-4	no	10.030	9.817	EPSD	COSMIC	5.767	Down-regulation
CMGC_CDK_CDK2_CDK3_ST	Q14934	NFATC4	Q00526	CDK3	S168	G163W	163	Missense	distal	-5	no	10.053	9.917	EPSD	COSMIC;GDSC;CCLE	5.767	Down-regulation
CMGC_CDK_CDK2_CDK3_ST	Q14934	NFATC4	Q00526	CDK3	S168	S168N	168	Missense	central	0	yes	10.053	0.000	EPSD	COSMIC	5.767	Loss
CMGC_CDK_CDK2_CDK3_ST	Q14934	NFATC4	Q00526	CDK3	S168	G163R	163	Missense	distal	-5	no	10.053	10.399	EPSD	COSMIC	5.767	Up-regulation
CMGC_CDK_CDK2_CDK3_ST	Q14934	NFATC4	Q00526	CDK3	S168	G162V	162	Missense	distal	-6	no	10.053	9.468	EPSD	COSMIC	5.767	Down-regulation
CMGC_CDK_CDK2_CDK3_ST	Q14934	NFATC4	Q00526	CDK3	S170	G163W	163	Missense	distal	-7	no	9.473	9.335	EPSD	COSMIC;GDSC;CCLE	5.767	Down-regulation
CMGC_CDK_CDK2_CDK3_ST	Q14934	NFATC4	Q00526	CDK3	S170	S168N	168	Missense	proximal	-2	no	9.473	9.637	EPSD	COSMIC	5.767	Up-regulation
CMGC_CDK_CDK2_CDK3_ST	Q14934	NFATC4	Q00526	CDK3	S170	G163R	163	Missense	distal	-7	no	9.473	9.547	EPSD	COSMIC	5.767	Up-regulation
CMGC_CDK_CDK2_CDK3_ST	Q14934	NFATC4	Q00526	CDK3	S213	R219I	219	Missense	distal	6	no	7.655	7.700	EPSD	COSMIC	5.767	Up-regulation
CMGC_CDK_CDK2_CDK3_ST	Q14934	NFATC4	Q00526	CDK3	S213	R208C	208	Missense	distal	-5	no	7.655	7.387	EPSD	COSMIC	5.767	Down-regulation
CMGC_CDK_CDK2_CDK3_ST	Q14934	NFATC4	Q00526	CDK3	S213	S217L	217	Missense	distal	4	no	7.655	7.566	EPSD	COSMIC;CCLE	5.767	Down-regulation
CMGC_CDK_CDK2_CDK3_ST	Q14934	NFATC4	Q00526	CDK3	S213	R219Q	219	Missense	distal	6	no	7.655	7.631	EPSD	COSMIC	5.767	Down-regulation
CMGC_CDK_CDK2_CDK3_ST	Q14934	NFATC4	Q00526	CDK3	S213	S207F	207	Missense	distal	-6	no	7.655	8.417	EPSD	COSMIC	5.767	Up-regulation
CMGC_CDK_CDK2_CDK3_ST	Q14934	NFATC4	Q00526	CDK3	S213	P216L	216	Missense	distal	3	no	7.655	5.457	EPSD	COSMIC	5.767	Loss
CMGC_CDK_CDK2_CDK3_ST	Q14934	NFATC4	Q00526	CDK3	S213	P214Q	214	Missense	proximal	1	no	7.655	1.768	EPSD	COSMIC	5.767	Loss
CMGC_CDK_CDK2_CDK3_ST	Q14934	NFATC4	Q00526	CDK3	S213	A206T	206	Missense	distal	-7	no	7.655	7.679	EPSD	COSMIC	5.767	Up-regulation
CMGC_CDK_CDK2_CDK3_ST	Q14934	NFATC4	Q00526	CDK3	S217	R219I	219	Missense	proximal	2	no	9.066	8.790	EPSD	COSMIC	5.767	Down-regulation
CMGC_CDK_CDK2_CDK3_ST	Q14934	NFATC4	Q00526	CDK3	S217	S217L	217	Missense	central	0	yes	9.066	0.000	EPSD	COSMIC;CCLE	5.767	Loss
CMGC_CDK_CDK2_CDK3_ST	Q14934	NFATC4	Q00526	CDK3	S217	R219Q	219	Missense	proximal	2	no	9.066	9.050	EPSD	COSMIC	5.767	Down-regulation
CMGC_CDK_CDK2_CDK3_ST	Q14934	NFATC4	Q00526	CDK3	S217	P216L	216	Missense	proximal	-1	no	9.066	9.081	EPSD	COSMIC	5.767	Up-regulation
CMGC_CDK_CDK2_CDK3_ST	Q14934	NFATC4	Q00526	CDK3	S217	P214Q	214	Missense	distal	-3	no	9.066	9.161	EPSD	COSMIC	5.767	Up-regulation
CMGC_CDK_CDK2_CDK3_ST	Q14934	NFATC4	Q00526	CDK3	S217	P224T	224	Missense	distal	7	no	9.066	9.139	EPSD	COSMIC	5.767	Up-regulation
CMGC_CDK_CDK2_CDK3_ST	Q14934	NFATC4	Q00526	CDK3	S217	R223W	223	Missense	distal	6	no	9.066	9.053	EPSD	COSMIC	5.767	Down-regulation
CMGC_CDK_CDK2_CDK3_ST	Q14934	NFATC4	Q00526	CDK3	S221	R219I	219	Missense	proximal	-2	no	10.708	10.656	EPSD	COSMIC	5.767	Down-regulation
CMGC_CDK_CDK2_CDK3_ST	Q14934	NFATC4	Q00526	CDK3	S221	P227Q	227	Missense	distal	6	no	10.708	10.705	EPSD	COSMIC	5.767	Down-regulation
CMGC_CDK_CDK2_CDK3_ST	Q14934	NFATC4	Q00526	CDK3	S221	P227H	227	Missense	distal	6	no	10.708	10.719	EPSD	COSMIC	5.767	Up-regulation
CMGC_CDK_CDK2_CDK3_ST	Q14934	NFATC4	Q00526	CDK3	S221	E228K	228	Missense	distal	7	no	10.708	10.679	EPSD	COSMIC	5.767	Down-regulation
CMGC_CDK_CDK2_CDK3_ST	Q14934	NFATC4	Q00526	CDK3	S221	S217L	217	Missense	distal	-4	no	10.708	9.338	EPSD	COSMIC;CCLE	5.767	Down-regulation
CMGC_CDK_CDK2_CDK3_ST	Q14934	NFATC4	Q00526	CDK3	S221	R219Q	219	Missense	proximal	-2	no	10.708	10.552	EPSD	COSMIC	5.767	Down-regulation
CMGC_CDK_CDK2_CDK3_ST	Q14934	NFATC4	Q00526	CDK3	S221	P216L	216	Missense	distal	-5	no	10.708	11.707	EPSD	COSMIC	5.767	Up-regulation
CMGC_CDK_CDK2_CDK3_ST	Q14934	NFATC4	Q00526	CDK3	S221	P214Q	214	Missense	distal	-7	no	10.708	10.930	EPSD	COSMIC	5.767	Up-regulation
CMGC_CDK_CDK2_CDK3_ST	Q14934	NFATC4	Q00526	CDK3	S221	P224T	224	Missense	distal	3	no	10.708	8.234	EPSD	COSMIC	5.767	Down-regulation
CMGC_CDK_CDK2_CDK3_ST	Q14934	NFATC4	Q00526	CDK3	S221	R223W	223	Missense	proximal	2	no	10.708	10.668	EPSD	COSMIC	5.767	Down-regulation
CMGC_CDK_CDK2_CDK3_ST	Q14934	NFATC4	Q00526	CDK3	S221	T226S	226	Missense	distal	5	no	10.708	10.504	EPSD	COSMIC	5.767	Down-regulation
CMGC_CDK_CDK2_CDK3_ST	Q14934	NFATC4	Q00526	CDK3	T226	R219I	219	Missense	distal	-7	no	7.527	7.507	EPSD	COSMIC	5.767	Down-regulation
CMGC_CDK_CDK2_CDK3_ST	Q14934	NFATC4	Q00526	CDK3	T226	P227Q	227	Missense	proximal	1	no	7.527	1.641	EPSD	COSMIC	5.767	Loss
CMGC_CDK_CDK2_CDK3_ST	Q14934	NFATC4	Q00526	CDK3	T226	P227H	227	Missense	proximal	1	no	7.527	1.430	EPSD	COSMIC	5.767	Loss
CMGC_CDK_CDK2_CDK3_ST	Q14934	NFATC4	Q00526	CDK3	T226	E228K	228	Missense	proximal	2	no	7.527	7.403	EPSD	COSMIC	5.767	Down-regulation
CMGC_CDK_CDK2_CDK3_ST	Q14934	NFATC4	Q00526	CDK3	T226	R219Q	219	Missense	distal	-7	no	7.527	7.216	EPSD	COSMIC	5.767	Down-regulation
CMGC_CDK_CDK2_CDK3_ST	Q14934	NFATC4	Q00526	CDK3	T226	P224T	224	Missense	proximal	-2	no	7.527	7.596	EPSD	COSMIC	5.767	Up-regulation
CMGC_CDK_CDK2_CDK3_ST	Q14934	NFATC4	Q00526	CDK3	T226	R223W	223	Missense	distal	-3	no	7.527	7.421	EPSD	COSMIC	5.767	Down-regulation
CMGC_CDK_CDK2_CDK3_ST	Q14934	NFATC4	Q00526	CDK3	T226	W231S	231	Missense	distal	5	no	7.527	7.273	EPSD	COSMIC	5.767	Down-regulation
CMGC_CDK_CDK2_CDK3_ST	Q14934	NFATC4	Q00526	CDK3	S237	G235S	235	Missense	proximal	-2	no	9.001	8.623	EPSD	COSMIC	5.767	Down-regulation
CMGC_CDK_CDK2_CDK3_ST	Q14934	NFATC4	Q00526	CDK3	S237	R241L	241	Missense	distal	4	no	9.001	9.079	EPSD	COSMIC	5.767	Up-regulation
CMGC_CDK_CDK2_CDK3_ST	Q14934	NFATC4	Q00526	CDK3	S237	R241Q	241	Missense	distal	4	no	9.001	9.142	EPSD	COSMIC	5.767	Up-regulation
CMGC_CDK_CDK2_CDK3_ST	Q14934	NFATC4	Q00526	CDK3	S237	W231S	231	Missense	distal	-6	no	9.001	8.446	EPSD	COSMIC	5.767	Down-regulation
CMGC_CDK_CDK2_CDK3_ST	Q14934	NFATC4	Q00526	CDK3	T256	P257S	257	Missense	proximal	1	no	11.077	6.013	EPSD	COSMIC	5.767	Down-regulation
CMGC_CDK_CDK2_CDK3_ST	Q14934	NFATC4	Q00526	CDK3	T256	R261W	261	Missense	distal	5	no	11.077	10.900	EPSD	COSMIC	5.767	Down-regulation
CMGC_CDK_CDK2_CDK3_ST	Q14934	NFATC4	Q00526	CDK3	T256	P253L	253	Missense	distal	-3	no	11.077	11.312	EPSD	COSMIC	5.767	Up-regulation
CMGC_CDK_CDK2_CDK3_ST	Q14934	NFATC4	Q00526	CDK3	T256	P260Q	260	Missense	distal	4	no	11.077	11.147	EPSD	COSMIC	5.767	Up-regulation
CMGC_CDK_CDK2_CDK3_ST	Q14934	NFATC4	Q00526	CDK3	T256	R261Q	261	Missense	distal	5	no	11.077	10.894	EPSD	COSMIC	5.767	Down-regulation
CMGC_CDK_CDK2_CDK3_ST	Q14934	NFATC4	Q00526	CDK3	T256	S259F	259	Missense	distal	3	no	11.077	10.699	EPSD	COSMIC	5.767	Down-regulation
CMGC_CDK_CDK2_CDK3_ST	Q14934	NFATC4	Q00526	CDK3	S259	P257S	257	Missense	proximal	-2	no	14.543	14.414	PhosphoSitePlus	COSMIC	5.767	Down-regulation
CMGC_CDK_CDK2_CDK3_ST	Q14934	NFATC4	Q00526	CDK3	S259	R261W	261	Missense	proximal	2	no	14.543	14.504	PhosphoSitePlus	COSMIC	5.767	Down-regulation
CMGC_CDK_CDK2_CDK3_ST	Q14934	NFATC4	Q00526	CDK3	S259	P253L	253	Missense	distal	-6	no	14.543	15.539	PhosphoSitePlus	COSMIC	5.767	Up-regulation
CMGC_CDK_CDK2_CDK3_ST	Q14934	NFATC4	Q00526	CDK3	S259	P260Q	260	Missense	proximal	1	no	14.543	8.657	PhosphoSitePlus	COSMIC	5.767	Down-regulation
CMGC_CDK_CDK2_CDK3_ST	Q14934	NFATC4	Q00526	CDK3	S259	R261Q	261	Missense	proximal	2	no	14.543	14.528	PhosphoSitePlus	COSMIC	5.767	Down-regulation
CMGC_CDK_CDK2_CDK3_ST	Q14934	NFATC4	Q00526	CDK3	S259	P265L	265	Missense	distal	6	no	14.543	14.547	PhosphoSitePlus	COSMIC	5.767	Up-regulation
CMGC_CDK_CDK2_CDK3_ST	Q14934	NFATC4	Q00526	CDK3	S259	S259F	259	Missense	central	0	yes	14.543	0.000	PhosphoSitePlus	COSMIC	5.767	Loss
CMGC_CDK_CDK2_CDK3_ST	Q14934	NFATC4	Q00526	CDK3	S264	S259F	259	Missense	distal	-5	no	5.312	6.150	EPSD	COSMIC	5.767	Gain
CMGC_CDK_CDK2_CDK3_ST	Q14934	NFATC4	Q00526	CDK3	S273	G275S	275	Missense	proximal	2	no	5.661	6.072	EPSD	COSMIC	5.767	Gain
CMGC_CDK_CDK2_CDK3_ST	Q14934	NFATC4	Q00526	CDK3	S273	R269Q	269	Missense	distal	-4	no	5.661	6.455	EPSD	COSMIC	5.767	Gain
CMGC_CDK_CDK2_CDK3_ST	Q14934	NFATC4	Q00526	CDK3	S273	R269W	269	Missense	distal	-4	no	5.661	6.199	EPSD	COSMIC	5.767	Gain
CMGC_CDK_CDK2_CDK3_ST	Q14934	NFATC4	Q00526	CDK3	T276	P277Q	277	Missense	proximal	1	no	8.554	2.668	EPSD	COSMIC	5.767	Loss
CMGC_CDK_CDK2_CDK3_ST	Q14934	NFATC4	Q00526	CDK3	T276	S272F	272	Missense	distal	-4	no	8.554	7.212	EPSD	COSMIC	5.767	Down-regulation
CMGC_CDK_CDK2_CDK3_ST	Q14934	NFATC4	Q00526	CDK3	T276	G275S	275	Missense	proximal	-1	no	8.554	8.545	EPSD	COSMIC	5.767	Down-regulation
CMGC_CDK_CDK2_CDK3_ST	Q14934	NFATC4	Q00526	CDK3	T276	S273L	273	Missense	distal	-3	no	8.554	8.750	EPSD	COSMIC	5.767	Up-regulation
CMGC_CDK_CDK2_CDK3_ST	Q14934	NFATC4	Q00526	CDK3	T276	P282A	282	Missense	distal	6	no	8.554	8.533	EPSD	COSMIC	5.767	Down-regulation
CMGC_CDK_CDK2_CDK3_ST	Q14934	NFATC4	Q00526	CDK3	T276	Y271H	271	Missense	distal	-5	no	8.554	8.707	EPSD	COSMIC	5.767	Up-regulation
CMGC_CDK_CDK2_CDK3_ST	Q14934	NFATC4	Q00526	CDK3	T276	R269Q	269	Missense	distal	-7	no	8.554	8.242	EPSD	COSMIC	5.767	Down-regulation
CMGC_CDK_CDK2_CDK3_ST	Q14934	NFATC4	Q00526	CDK3	T276	S272P	272	Missense	distal	-4	no	8.554	7.834	EPSD	COSMIC	5.767	Down-regulation
CMGC_CDK_CDK2_CDK3_ST	Q14934	NFATC4	Q00526	CDK3	T276	R269W	269	Missense	distal	-7	no	8.554	8.343	EPSD	COSMIC	5.767	Down-regulation
CMGC_CDK_CDK2_CDK3_ST	Q14934	NFATC4	Q00526	CDK3	T276	S281F	281	Missense	distal	5	no	8.554	8.870	EPSD	COSMIC	5.767	Up-regulation
CMGC_CDK_CDK2_CDK3_ST	Q14934	NFATC4	Q00526	CDK3	T276	R270H	270	Missense	distal	-6	no	8.554	8.408	EPSD	COSMIC	5.767	Down-regulation
CMGC_CDK_CDK2_CDK3_ST	Q14934	NFATC4	Q00526	CDK3	T276	R270C	270	Missense	distal	-6	no	8.554	8.393	EPSD	COSMIC	5.767	Down-regulation
CMGC_CDK_CDK2_CDK3_ST	Q14934	NFATC4	Q00526	CDK3	T276	S274L	274	Missense	proximal	-2	no	8.554	8.951	EPSD	COSMIC	5.767	Up-regulation
CMGC_CDK_CDK2_CDK3_ST	Q14934	NFATC4	Q00526	CDK3	S278	S273L	273	Missense	distal	-5	no	4.444	6.009	EPSD	COSMIC	5.767	Gain
CMGC_CDK_CDK2_CDK3_ST	Q14934	NFATC4	Q00526	CDK3	S281	R286W	286	Missense	distal	5	no	7.994	7.817	EPSD	COSMIC	5.767	Down-regulation
CMGC_CDK_CDK2_CDK3_ST	Q14934	NFATC4	Q00526	CDK3	S281	P277Q	277	Missense	distal	-4	no	7.994	7.814	EPSD	COSMIC	5.767	Down-regulation
CMGC_CDK_CDK2_CDK3_ST	Q14934	NFATC4	Q00526	CDK3	S281	S285P	285	Missense	distal	4	no	7.994	7.899	EPSD	COSMIC	5.767	Down-regulation
CMGC_CDK_CDK2_CDK3_ST	Q14934	NFATC4	Q00526	CDK3	S281	G275S	275	Missense	distal	-6	no	7.994	7.089	EPSD	COSMIC	5.767	Down-regulation
CMGC_CDK_CDK2_CDK3_ST	Q14934	NFATC4	Q00526	CDK3	S281	G288W	288	Missense	distal	7	no	7.994	7.993	EPSD	COSMIC	5.767	Down-regulation
CMGC_CDK_CDK2_CDK3_ST	Q14934	NFATC4	Q00526	CDK3	S281	P282A	282	Missense	proximal	1	no	7.994	2.588	EPSD	COSMIC	5.767	Loss
CMGC_CDK_CDK2_CDK3_ST	Q14934	NFATC4	Q00526	CDK3	S281	R286H	286	Missense	distal	5	no	7.994	7.887	EPSD	COSMIC	5.767	Down-regulation
CMGC_CDK_CDK2_CDK3_ST	Q14934	NFATC4	Q00526	CDK3	S281	R287H	287	Missense	distal	6	no	7.994	7.984	EPSD	COSMIC	5.767	Down-regulation
CMGC_CDK_CDK2_CDK3_ST	Q14934	NFATC4	Q00526	CDK3	S281	R287S	287	Missense	distal	6	no	7.994	7.937	EPSD	COSMIC	5.767	Down-regulation
CMGC_CDK_CDK2_CDK3_ST	Q14934	NFATC4	Q00526	CDK3	S281	S281F	281	Missense	central	0	yes	7.994	0.000	EPSD	COSMIC	5.767	Loss
CMGC_CDK_CDK2_CDK3_ST	Q14934	NFATC4	Q00526	CDK3	S281	S274L	274	Missense	distal	-7	no	7.994	8.471	EPSD	COSMIC	5.767	Up-regulation
CMGC_CDK_CDK2_CDK3_ST	Q14934	NFATC4	Q00526	CDK3	S295	P301S	301	Missense	distal	6	no	7.866	7.830	EPSD	COSMIC	5.767	Down-regulation
CMGC_CDK_CDK2_CDK3_ST	Q14934	NFATC4	Q00526	CDK3	S295	G288W	288	Missense	distal	-7	no	7.866	7.729	EPSD	COSMIC	5.767	Down-regulation
CMGC_CDK_CDK2_CDK3_ST	Q14934	NFATC4	Q00526	CDK3	S295	P302L	302	Missense	distal	7	no	7.866	7.940	EPSD	COSMIC	5.767	Up-regulation
CMGC_CDK_CDK2_CDK3_ST	Q14934	NFATC4	Q00526	CDK3	S295	P301L	301	Missense	distal	6	no	7.866	7.869	EPSD	COSMIC	5.767	Up-regulation
CMGC_CDK_CDK2_CDK3_ST	Q14934	NFATC4	Q00526	CDK3	S295	P300S	300	Missense	distal	5	no	7.866	7.813	EPSD	COSMIC	5.767	Down-regulation
CMGC_CDK_CDK2_CDK3_ST	Q14934	NFATC4	Q00526	CDK3	S295	P302T	302	Missense	distal	7	no	7.866	7.939	EPSD	COSMIC	5.767	Up-regulation
CMGC_CDK_CDK2_CDK3_ST	Q14934	NFATC4	Q00526	CDK3	S295	G291R	291	Missense	distal	-4	no	7.866	7.589	EPSD	COSMIC	5.767	Down-regulation
CMGC_CDK_CDK2_CDK3_ST	Q14934	NFATC4	Q00526	CDK3	S295	P299S	299	Missense	distal	4	no	7.866	7.961	EPSD	COSMIC	5.767	Up-regulation
CMGC_CDK_CDK2_CDK3_ST	Q14934	NFATC4	Q00526	CDK3	S295	G294E	294	Missense	proximal	-1	no	7.866	7.868	EPSD	COSMIC	5.767	Up-regulation
CMGC_CDK_CDK2_CDK3_ST	Q14934	NFATC4	Q00526	CDK3	S311	P314S	314	Missense	distal	3	no	13.286	11.123	EPSD	COSMIC	5.767	Down-regulation
CMGC_CDK_CDK2_CDK3_ST	Q14934	NFATC4	Q00526	CDK3	S311	P312S	312	Missense	proximal	1	no	13.286	8.222	EPSD	COSMIC	5.767	Down-regulation
CMGC_CDK_CDK2_CDK3_ST	Q14934	NFATC4	Q00526	CDK3	S311	P304L	304	Missense	distal	-7	no	13.286	13.777	EPSD	COSMIC	5.767	Up-regulation
CMGC_CDK_CDK2_CDK3_ST	Q14934	NFATC4	Q00526	CDK3	S311	D316Y	316	Missense	distal	5	no	13.286	13.351	EPSD	COSMIC	5.767	Up-regulation
CMGC_CDK_CDK2_CDK3_ST	Q14934	NFATC4	Q00526	CDK3	S311	F315L	315	Missense	distal	4	no	13.286	13.309	EPSD	COSMIC;CCLE	5.767	Up-regulation
CMGC_CDK_CDK2_CDK3_ST	Q14934	NFATC4	Q00526	CDK3	S334	S335P	335	Missense	proximal	1	no	2.371	7.435	EPSD	COSMIC	5.767	Gain
CMGC_CDK_CDK2_CDK3_ST	Q14934	NFATC4	Q00526	CDK3	S382	D376N	376	Missense	distal	-6	no	7.933	8.160	EPSD	COSMIC	5.767	Up-regulation
CMGC_CDK_CDK2_CDK3_ST	Q14934	NFATC4	Q00526	CDK3	S382	V380A	380	Missense	proximal	-2	no	7.933	7.852	EPSD	COSMIC	5.767	Down-regulation
CMGC_CDK_CDK2_CDK3_ST	Q14934	NFATC4	Q00526	CDK3	S382	P383T	383	Missense	proximal	1	no	7.933	1.728	EPSD	COSMIC	5.767	Loss
CMGC_CDK_CDK2_CDK3_ST	Q14934	NFATC4	Q00526	CDK3	S382	S387F	387	Missense	distal	5	no	7.933	8.249	EPSD	COSMIC	5.767	Up-regulation
CMGC_CDK_CDK2_CDK3_ST	Q14934	NFATC4	Q00526	CDK3	S382	D376Y	376	Missense	distal	-6	no	7.933	8.085	EPSD	COSMIC	5.767	Up-regulation
CMGC_CDK_CDK2_CDK3_ST	Q14934	NFATC4	Q00526	CDK3	S395	P396T	396	Missense	proximal	1	no	8.450	2.245	EPSD	COSMIC	5.767	Loss
CMGC_CDK_CDK2_CDK3_ST	Q14934	NFATC4	Q00526	CDK3	S395	A402V	402	Missense	distal	7	no	8.450	8.446	EPSD	COSMIC	5.767	Down-regulation
CMGC_CDK_CDK2_CDK3_ST	Q14934	NFATC4	Q00526	CDK3	S395	R399K	399	Missense	distal	4	no	8.450	8.554	EPSD	COSMIC	5.767	Up-regulation
CMGC_CDK_CDK2_CDK3_ST	Q14934	NFATC4	Q00526	CDK3	S395	G392V	392	Missense	distal	-3	no	8.450	8.254	EPSD	COSMIC	5.767	Down-regulation
CMGC_CDK_CDK2_CDK3_ST	Q14934	NFATC4	Q00526	CDK3	S395	F398S	398	Missense	distal	3	no	8.450	8.828	EPSD	COSMIC	5.767	Up-regulation
CMGC_CDK_CDK2_CDK3_ST	Q14934	NFATC4	Q00526	CDK3	S395	I391T	391	Missense	distal	-4	no	8.450	9.287	EPSD	COSMIC	5.767	Up-regulation
CMGC_CDK_CDK2_CDK3_ST	Q14934	NFATC4	Q00526	CDK3	S395	S395I	395	Missense	central	0	yes	8.450	0.000	EPSD	COSMIC	5.767	Loss
CMGC_CDK_CDK2_CDK3_ST	Q14934	NFATC4	Q00526	CDK3	S592	E589K	589	Missense	distal	-3	no	8.336	8.243	EPSD	COSMIC	5.767	Down-regulation
CMGC_CDK_CDK2_CDK3_ST	Q14934	NFATC4	Q00526	CDK3	S592	S594L	594	Missense	proximal	2	no	8.336	7.892	EPSD	COSMIC	5.767	Down-regulation
CMGC_CDK_CDK2_CDK3_ST	Q14934	NFATC4	Q00526	CDK3	S592	P586H	586	Missense	distal	-6	no	8.336	8.807	EPSD	COSMIC	5.767	Up-regulation
CMGC_CDK_CDK2_CDK3_ST	Q14934	NFATC4	Q00526	CDK3	S592	P593S	593	Missense	proximal	1	no	8.336	3.273	EPSD	COSMIC	5.767	Loss
CMGC_CDK_CDK2_CDK3_ST	Q14934	NFATC4	Q00526	CDK3	S592	R599I	599	Missense	distal	7	no	8.336	8.339	EPSD	COSMIC	5.767	Up-regulation
CMGC_CDK_CDK2_CDK3_ST	Q14934	NFATC4	Q00526	CDK3	S592	S594R	594	Missense	proximal	2	no	8.336	8.092	EPSD	COSMIC	5.767	Down-regulation
CMGC_CDK_CDK2_CDK3_ST	Q14934	NFATC4	Q00526	CDK3	S676	P677A	677	Missense	proximal	1	no	7.266	1.860	EPSD	COSMIC	5.767	Loss
CMGC_CDK_CDK2_CDK3_ST	Q14934	NFATC4	Q00526	CDK3	S676	S676N	676	Missense	central	0	yes	7.266	0.000	EPSD	COSMIC	5.767	Loss
CMGC_CDK_CDK2_CDK3_ST	Q14934	NFATC4	Q00526	CDK3	S676	G671W	671	Missense	distal	-5	no	7.266	7.130	EPSD	COSMIC	5.767	Down-regulation
CMGC_CDK_CDK2_CDK3_ST	Q14934	NFATC4	Q00526	CDK3	S676	R675H	675	Missense	proximal	-1	no	7.266	7.260	EPSD	COSMIC;CCLE	5.767	Down-regulation
CMGC_CDK_CDK2_CDK3_ST	Q14934	NFATC4	Q00526	CDK3	S676	R672W	672	Missense	distal	-4	no	7.266	7.804	EPSD	COSMIC	5.767	Up-regulation
CMGC_CDK_CDK2_CDK3_ST	Q14934	NFATC4	Q00526	CDK3	S676	S669A	669	Missense	distal	-7	no	7.266	7.499	EPSD	COSMIC	5.767	Up-regulation
CMGC_CDK_CDK2_CDK3_ST	Q14934	NFATC4	Q00526	CDK3	S676	G671R	671	Missense	distal	-5	no	7.266	7.612	EPSD	COSMIC	5.767	Up-regulation
CMGC_CDK_CDK2_CDK3_ST	Q14934	NFATC4	Q00526	CDK3	S676	R675C	675	Missense	proximal	-1	no	7.266	7.259	EPSD	COSMIC	5.767	Down-regulation
CMGC_CDK_CDK2_CDK3_ST	Q14934	NFATC4	Q00526	CDK3	S716	P723L	723	Missense	distal	7	no	10.253	10.328	EPSD	COSMIC	5.767	Up-regulation
CMGC_CDK_CDK2_CDK3_ST	Q14934	NFATC4	Q00526	CDK3	S716	P721H	721	Missense	distal	5	no	10.253	10.524	EPSD	COSMIC	5.767	Up-regulation
CMGC_CDK_CDK2_CDK3_ST	Q14934	NFATC4	Q00526	CDK3	S716	F709C	709	Missense	distal	-7	no	10.253	10.227	EPSD	COSMIC	5.767	Down-regulation
CMGC_CDK_CDK2_CDK3_ST	Q14934	NFATC4	Q00526	CDK3	S716	R719K	719	Missense	distal	3	no	10.253	11.643	EPSD	COSMIC	5.767	Up-regulation
CMGC_CDK_CDK2_CDK3_ST	Q14934	NFATC4	Q00526	CDK3	S716	P723S	723	Missense	distal	7	no	10.253	10.303	EPSD	COSMIC	5.767	Up-regulation
CMGC_CDK_CDK2_CDK3_ST	Q14934	NFATC4	Q00526	CDK3	S819	G824C	824	Missense	distal	5	no	8.863	8.772	EPSD	COSMIC;CCLE	5.767	Down-regulation
CMGC_CDK_CDK2_CDK3_ST	Q14934	NFATC4	Q00526	CDK3	S819	P817S	817	Missense	proximal	-2	no	8.863	8.733	EPSD	COSMIC	5.767	Down-regulation
CMGC_CDK_CDK2_CDK3_ST	Q14934	NFATC4	Q00526	CDK3	S819	P820A	820	Missense	proximal	1	no	8.863	3.457	EPSD	COSMIC	5.767	Loss
CMGC_CDK_CDK2_CDK3_ST	Q14934	NFATC4	Q00526	CDK3	S819	S819F	819	Missense	central	0	yes	8.863	0.000	EPSD	COSMIC	5.767	Loss
CMGC_CDK_CDK2_CDK3_ST	Q14934	NFATC4	Q00526	CDK3	S819	A818S	818	Missense	proximal	-1	no	8.863	8.857	EPSD	COSMIC	5.767	Down-regulation
CMGC_CDK_CDK2_CDK3_ST	Q14934	NFATC4	Q00526	CDK3	S819	P825S	825	Missense	distal	6	no	8.863	8.827	EPSD	COSMIC	5.767	Down-regulation
CMGC_CDK_CDK2_CDK3_ST	Q14934	NFATC4	Q00526	CDK3	S819	P815H	815	Missense	distal	-4	no	8.863	8.269	EPSD	COSMIC	5.767	Down-regulation
CMGC_CDK_CDK2_CDK3_ST	Q14934	NFATC4	Q00526	CDK3	S819	P813S	813	Missense	distal	-6	no	8.863	8.498	EPSD	COSMIC	5.767	Down-regulation
CMGC_CDK_CDK2_CDK3_ST	Q14934	NFATC4	Q00526	CDK3	S819	E823A	823	Missense	distal	4	no	8.863	8.955	EPSD	COSMIC	5.767	Up-regulation
CMGC_CDK_CDK2_CDK3_ST	Q14934	NFATC4	Q00526	CDK3	S819	R812W	812	Missense	distal	-7	no	8.863	8.652	EPSD	COSMIC	5.767	Down-regulation
CMGC_CDK_CDK2_CDK3_ST	Q14934	NFATC4	Q00526	CDK3	S819	F826Y	826	Missense	distal	7	no	8.863	8.850	EPSD	COSMIC	5.767	Down-regulation
CMGC_CDK_CDK2_CDK3_ST	Q14934	NFATC4	Q00526	CDK3	S819	P815S	815	Missense	distal	-4	no	8.863	9.583	EPSD	COSMIC	5.767	Up-regulation
CMGC_CDK_CDK2_CDK3_ST	P03372	ESR1	Q00526	CDK3	S46	S47T	47	Missense	proximal	1	no	6.525	5.384	EPSD	COSMIC	5.767	Loss
CMGC_CDK_CDK2_CDK3_ST	P03372	ESR1	Q00526	CDK3	S46	A50T	50	Missense	distal	4	no	6.525	6.482	EPSD	COSMIC	5.767	Down-regulation
CMGC_CDK_CDK2_CDK3_ST	P03372	ESR1	Q00526	CDK3	S46	K48N	48	Missense	proximal	2	no	6.525	6.632	EPSD	COSMIC	5.767	Up-regulation
CMGC_CDK_CDK2_CDK3_ST	P03372	ESR1	Q00526	CDK3	S46	D45N	45	Missense	proximal	-1	no	6.525	6.522	EPSD	COSMIC	5.767	Down-regulation
CMGC_CDK_CDK2_CDK3_ST	P03372	ESR1	Q00526	CDK3	S46	P49S	49	Missense	distal	3	no	6.525	4.363	EPSD	COSMIC	5.767	Loss
CMGC_CDK_CDK2_CDK3_ST	P03372	ESR1	Q00526	CDK3	S47	P49S	49	Missense	proximal	2	no	5.262	5.793	EPSD	COSMIC	5.767	Gain
CMGC_CDK_CDK2_CDK3_ST	P03372	ESR1	Q00526	CDK3	S102	F97L	97	Missense	distal	-5	no	6.023	6.749	EPSD	COSMIC	5.767	Up-regulation
CMGC_CDK_CDK2_CDK3_ST	P03372	ESR1	Q00526	CDK3	S102	M109T	109	Missense	distal	7	no	6.023	6.056	EPSD	COSMIC	5.767	Up-regulation
CMGC_CDK_CDK2_CDK3_ST	P03372	ESR1	Q00526	CDK3	S104	F97L	97	Missense	distal	-7	no	14.135	14.217	EPSD;PhosphoSitePlus	COSMIC	5.767	Up-regulation
CMGC_CDK_CDK2_CDK3_ST	P03372	ESR1	Q00526	CDK3	S104	M109T	109	Missense	distal	5	no	14.135	13.984	EPSD;PhosphoSitePlus	COSMIC	5.767	Down-regulation
CMGC_CDK_CDK2_CDK3_ST	P03372	ESR1	Q00526	CDK3	S106	P113L	113	Missense	distal	7	no	13.716	13.790	EPSD;PhosphoSitePlus	COSMIC	5.767	Up-regulation
CMGC_CDK_CDK2_CDK3_ST	P03372	ESR1	Q00526	CDK3	S106	P113Q	113	Missense	distal	7	no	13.716	13.776	EPSD;PhosphoSitePlus	COSMIC	5.767	Up-regulation
CMGC_CDK_CDK2_CDK3_ST	P03372	ESR1	Q00526	CDK3	S106	H112L	112	Missense	distal	6	no	13.716	13.708	EPSD;PhosphoSitePlus	COSMIC	5.767	Down-regulation
CMGC_CDK_CDK2_CDK3_ST	P03372	ESR1	Q00526	CDK3	S106	M109T	109	Missense	distal	3	no	13.716	13.259	EPSD;PhosphoSitePlus	COSMIC	5.767	Down-regulation
CMGC_CDK_CDK2_CDK3_ST	P03372	ESR1	Q00526	CDK3	S118	P113L	113	Missense	distal	-5	no	13.277	14.276	PhosphoSitePlus;EPSD	COSMIC	5.767	Up-regulation
CMGC_CDK_CDK2_CDK3_ST	P03372	ESR1	Q00526	CDK3	S118	P113Q	113	Missense	distal	-5	no	13.277	13.364	PhosphoSitePlus;EPSD	COSMIC	5.767	Up-regulation
CMGC_CDK_CDK2_CDK3_ST	P03372	ESR1	Q00526	CDK3	S118	L117Q	117	Missense	proximal	-1	no	13.277	13.264	PhosphoSitePlus;EPSD	COSMIC	5.767	Down-regulation
CMGC_CDK_CDK2_CDK3_ST	P03372	ESR1	Q00526	CDK3	S118	H112L	112	Missense	distal	-6	no	13.277	13.802	PhosphoSitePlus;EPSD	COSMIC	5.767	Up-regulation
CMGC_CDK_CDK2_CDK3_ST	P03372	ESR1	Q00526	CDK3	S118	S118P	118	Missense	central	0	yes	13.277	0.000	PhosphoSitePlus;EPSD	COSMIC	5.767	Loss
CMGC_CDK_CDK2_CDK3_ST	P03372	ESR1	Q00526	CDK3	S294	K299R	299	Missense	distal	5	no	9.470	9.751	EPSD	COSMIC	5.767	Up-regulation
CMGC_CDK_CDK2_CDK3_ST	P03372	ESR1	Q00526	CDK3	S294	P295L	295	Missense	proximal	1	no	9.470	2.726	EPSD	COSMIC	5.767	Loss
CMGC_CDK_CDK2_CDK3_ST	P03372	ESR1	Q00526	CDK3	S294	R300C	300	Missense	distal	6	no	9.470	9.457	EPSD	COSMIC;CCLE	5.767	Down-regulation
CMGC_CDK_CDK2_CDK3_ST	P03372	ESR1	Q00526	CDK3	S294	L296P	296	Missense	proximal	2	no	9.470	9.383	EPSD	COSMIC	5.767	Down-regulation
CMGC_CDK_CDK2_CDK3_ST	P03372	ESR1	Q00526	CDK3	S294	N290K	290	Missense	distal	-4	no	9.470	8.810	EPSD	COSMIC	5.767	Down-regulation
CMGC_CDK_CDK2_CDK3_ST	P03372	ESR1	Q00526	CDK3	S294	S294R	294	Missense	central	0	yes	9.470	0.000	EPSD	COSMIC	5.767	Loss
CMGC_CDK_CDK2_CDK3_ST	P03372	ESR1	Q00526	CDK3	S294	A288T	288	Missense	distal	-6	no	9.470	9.591	EPSD	COSMIC	5.767	Up-regulation
CMGC_CDK_CDK2_CDK3_ST	P03372	ESR1	Q00526	CDK3	S294	R287H	287	Missense	distal	-7	no	9.470	9.249	EPSD	COSMIC	5.767	Down-regulation
CMGC_CDK_CDK2_CDK3_ST	P03372	ESR1	Q00526	CDK3	S294	R287C	287	Missense	distal	-7	no	9.470	9.320	EPSD	COSMIC	5.767	Down-regulation
CMGC_CDK_CDK2_CDK3_ST	P46531	NOTCH1	Q00526	CDK3	T535	C532W	532	Missense	distal	-3	no	10.243	10.212	EPSD	COSMIC	5.767	Down-regulation
CMGC_CDK_CDK2_CDK3_ST	P46531	NOTCH1	Q00526	CDK3	T535	E531K	531	Missense	distal	-4	no	10.243	10.295	EPSD	COSMIC	5.767	Up-regulation
CMGC_CDK_CDK2_CDK3_ST	P46531	NOTCH1	Q00526	CDK3	T535	P536L	536	Missense	proximal	1	no	10.243	3.498	EPSD	COSMIC	5.767	Loss
CMGC_CDK_CDK2_CDK3_ST	P46531	NOTCH1	Q00526	CDK3	T1861	E1866K	1866	Missense	distal	5	no	6.686	6.528	EPSD	COSMIC	5.767	Down-regulation
CMGC_CDK_CDK2_CDK3_ST	P46531	NOTCH1	Q00526	CDK3	T1861	M1855V	1855	Missense	distal	-6	no	6.686	6.334	EPSD	COSMIC	5.767	Down-regulation
CMGC_CDK_CDK2_CDK3_ST	P46531	NOTCH1	Q00526	CDK3	T1861	V1867I	1867	Missense	distal	6	no	6.686	6.791	EPSD	COSMIC	5.767	Up-regulation
CMGC_CDK_CDK2_CDK3_ST	P46531	NOTCH1	Q00526	CDK3	T1861	S1856C	1856	Missense	distal	-5	no	6.686	7.577	EPSD	COSMIC	5.767	Up-regulation
CMGC_CDK_CDK2_CDK3_ST	P46531	NOTCH1	Q00526	CDK3	T1861	Q1864R	1864	Missense	distal	3	no	6.686	6.315	EPSD	COSMIC	5.767	Down-regulation
CMGC_CDK_CDK2_CDK3_ST	P46531	NOTCH1	Q00526	CDK3	T1861	M1858L	1858	Missense	distal	-3	no	6.686	6.784	EPSD	COSMIC	5.767	Up-regulation
CMGC_CDK_CDK2_CDK3_ST	P46531	NOTCH1	Q00526	CDK3	T1861	P1860L	1860	Missense	proximal	-1	no	6.686	6.702	EPSD	COSMIC	5.767	Up-regulation
CMGC_CDK_CDK2_CDK3_ST	P46531	NOTCH1	Q00526	CDK3	S1941	A1943V	1943	Missense	proximal	2	no	6.027	6.080	EPSD	COSMIC	5.767	Up-regulation
CMGC_CDK_CDK2_CDK3_ST	P46531	NOTCH1	Q00526	CDK3	S1941	A1944T	1944	Missense	distal	3	no	6.027	5.393	EPSD	COSMIC;CCLE	5.767	Loss
CMGC_CDK_CDK2_CDK3_ST	P46531	NOTCH1	Q00526	CDK3	S1941	R1937C	1937	Missense	distal	-4	no	6.027	6.559	EPSD	COSMIC	5.767	Up-regulation
CMGC_CDK_CDK2_CDK3_ST	P46531	NOTCH1	Q00526	CDK3	S1941	S1941F	1941	Missense	central	0	yes	6.027	0.000	EPSD	COSMIC	5.767	Loss
CMGC_CDK_CDK2_CDK3_ST	P46531	NOTCH1	Q00526	CDK3	S1941	R1940C	1940	Missense	proximal	-1	no	6.027	6.020	EPSD	COSMIC	5.767	Down-regulation
CMGC_CDK_CDK2_CDK3_ST	P46531	NOTCH1	Q00526	CDK3	S1941	A1935V	1935	Missense	distal	-6	no	6.027	5.982	EPSD	COSMIC	5.767	Down-regulation
CMGC_CDK_CDK2_CDK3_ST	P46531	NOTCH1	Q00526	CDK3	T1986	R1984Q	1984	Missense	proximal	-2	no	6.356	6.200	EPSD	COSMIC;GDSC;CCLE	5.767	Down-regulation
CMGC_CDK_CDK2_CDK3_ST	P46531	NOTCH1	Q00526	CDK3	T1986	R1982Q	1982	Missense	distal	-4	no	6.356	7.150	EPSD	COSMIC	5.767	Up-regulation
CMGC_CDK_CDK2_CDK3_ST	P46531	NOTCH1	Q00526	CDK3	T1997	A2002V	2002	Missense	distal	5	no	7.292	7.357	EPSD	COSMIC	5.767	Up-regulation
CMGC_CDK_CDK2_CDK3_ST	P46531	NOTCH1	Q00526	CDK3	T1997	R2004H	2004	Missense	distal	7	no	7.292	7.268	EPSD	COSMIC	5.767	Down-regulation
CMGC_CDK_CDK2_CDK3_ST	P46531	NOTCH1	Q00526	CDK3	S2121	E2115K	2115	Missense	distal	-6	no	9.030	8.859	EPSD	COSMIC	5.767	Down-regulation
CMGC_CDK_CDK2_CDK3_ST	P46531	NOTCH1	Q00526	CDK3	S2121	N2117S	2117	Missense	distal	-4	no	9.030	9.522	EPSD	COSMIC	5.767	Up-regulation
CMGC_CDK_CDK2_CDK3_ST	P46531	NOTCH1	Q00526	CDK3	S2121	P2122L	2122	Missense	proximal	1	no	9.030	2.285	EPSD	COSMIC	5.767	Loss
CMGC_CDK_CDK2_CDK3_ST	P46531	NOTCH1	Q00526	CDK3	S2121	E2115V	2115	Missense	distal	-6	no	9.030	8.712	EPSD	COSMIC	5.767	Down-regulation
CMGC_CDK_CDK2_CDK3_ST	P46531	NOTCH1	Q00526	CDK3	S2121	N2117K	2117	Missense	distal	-4	no	9.030	8.370	EPSD	COSMIC;GDSC;CCLE	5.767	Down-regulation
CMGC_CDK_CDK2_CDK3_ST	P46531	NOTCH1	Q00526	CDK3	T2132	P2133A	2133	Missense	proximal	1	no	8.693	3.287	EPSD	COSMIC	5.767	Loss
CMGC_CDK_CDK2_CDK3_ST	P46531	NOTCH1	Q00526	CDK3	T2132	L2139F	2139	Missense	distal	7	no	8.693	8.696	EPSD	COSMIC	5.767	Up-regulation
CMGC_CDK_CDK2_CDK3_ST	P46531	NOTCH1	Q00526	CDK3	T2132	G2131N	2131	Missense	proximal	-1	no	8.693	8.688	EPSD	COSMIC	5.767	Down-regulation
CMGC_CDK_CDK2_CDK3_ST	P46531	NOTCH1	Q00526	CDK3	T2132	T2132M	2132	Missense	central	0	yes	8.693	0.000	EPSD	COSMIC	5.767	Loss
CMGC_CDK_CDK2_CDK3_ST	P46531	NOTCH1	Q00526	CDK3	T2132	L2139P	2139	Missense	distal	7	no	8.693	8.619	EPSD	COSMIC	5.767	Down-regulation
CMGC_CDK_CDK2_CDK3_ST	P46531	NOTCH1	Q00526	CDK3	T2132	L2129V	2129	Missense	distal	-3	no	8.693	8.513	EPSD	COSMIC	5.767	Down-regulation
CMGC_CDK_CDK2_CDK3_ST	P46531	NOTCH1	Q00526	CDK3	S2136	P2133A	2133	Missense	distal	-3	no	8.121	8.151	EPSD	COSMIC	5.767	Up-regulation
CMGC_CDK_CDK2_CDK3_ST	P46531	NOTCH1	Q00526	CDK3	S2136	L2139F	2139	Missense	distal	3	no	8.121	7.779	EPSD	COSMIC	5.767	Down-regulation
CMGC_CDK_CDK2_CDK3_ST	P46531	NOTCH1	Q00526	CDK3	S2136	G2131N	2131	Missense	distal	-5	no	8.121	7.783	EPSD	COSMIC	5.767	Down-regulation
CMGC_CDK_CDK2_CDK3_ST	P46531	NOTCH1	Q00526	CDK3	S2136	T2132M	2132	Missense	distal	-4	no	8.121	7.381	EPSD	COSMIC	5.767	Down-regulation
CMGC_CDK_CDK2_CDK3_ST	P46531	NOTCH1	Q00526	CDK3	S2136	L2139P	2139	Missense	distal	3	no	8.121	10.319	EPSD	COSMIC	5.767	Up-regulation
CMGC_CDK_CDK2_CDK3_ST	P46531	NOTCH1	Q00526	CDK3	S2136	L2129V	2129	Missense	distal	-7	no	8.121	7.835	EPSD	COSMIC	5.767	Down-regulation
CMGC_CDK_CDK2_CDK3_ST	P46531	NOTCH1	Q00526	CDK3	S2136	C2140Y	2140	Missense	distal	4	no	8.121	8.036	EPSD	COSMIC	5.767	Down-regulation
CMGC_CDK_CDK2_CDK3_ST	P46531	NOTCH1	Q00526	CDK3	S2141	L2139F	2139	Missense	proximal	-2	no	11.515	11.379	EPSD	COSMIC	5.767	Down-regulation
CMGC_CDK_CDK2_CDK3_ST	P46531	NOTCH1	Q00526	CDK3	S2141	L2139P	2139	Missense	proximal	-2	no	11.515	11.247	EPSD	COSMIC	5.767	Down-regulation
CMGC_CDK_CDK2_CDK3_ST	P46531	NOTCH1	Q00526	CDK3	S2141	S2148R	2148	Missense	distal	7	no	11.515	11.543	EPSD	COSMIC	5.767	Up-regulation
CMGC_CDK_CDK2_CDK3_ST	P46531	NOTCH1	Q00526	CDK3	S2141	C2140Y	2140	Missense	proximal	-1	no	11.515	11.513	EPSD	COSMIC	5.767	Down-regulation
CMGC_CDK_CDK2_CDK3_ST	P46531	NOTCH1	Q00526	CDK3	S2148	L2149P	2149	Missense	proximal	1	no	4.408	11.153	EPSD	COSMIC	5.767	Gain
CMGC_CDK_CDK2_CDK3_ST	P46531	NOTCH1	Q00526	CDK3	S2163	V2158G	2158	Missense	distal	-5	no	6.163	6.484	EPSD	COSMIC	5.767	Up-regulation
CMGC_CDK_CDK2_CDK3_ST	P46531	NOTCH1	Q00526	CDK3	S2163	R2159H	2159	Missense	distal	-4	no	6.163	6.542	EPSD	COSMIC	5.767	Up-regulation
CMGC_CDK_CDK2_CDK3_ST	P46531	NOTCH1	Q00526	CDK3	S2163	S2162I	2162	Missense	proximal	-1	no	6.163	6.179	EPSD	COSMIC	5.767	Up-regulation
CMGC_CDK_CDK2_CDK3_ST	P46531	NOTCH1	Q00526	CDK3	S2215	S2221F	2221	Missense	distal	6	no	10.376	10.418	EPSD	COSMIC	5.767	Up-regulation
CMGC_CDK_CDK2_CDK3_ST	P46531	NOTCH1	Q00526	CDK3	S2215	S2215L	2215	Missense	central	0	yes	10.376	0.000	EPSD	COSMIC;GDSC;CCLE	5.767	Loss
CMGC_CDK_CDK2_CDK3_ST	P46531	NOTCH1	Q00526	CDK3	S2215	D2212N	2212	Missense	distal	-3	no	10.376	10.391	EPSD	COSMIC	5.767	Up-regulation
CMGC_CDK_CDK2_CDK3_ST	P46531	NOTCH1	Q00526	CDK3	S2221	S2221F	2221	Missense	central	0	yes	11.378	0.000	EPSD	COSMIC	5.767	Loss
CMGC_CDK_CDK2_CDK3_ST	P46531	NOTCH1	Q00526	CDK3	S2221	S2215L	2215	Missense	distal	-6	no	11.378	12.739	EPSD	COSMIC;GDSC;CCLE	5.767	Up-regulation
CMGC_CDK_CDK2_CDK3_ST	P46531	NOTCH1	Q00526	CDK3	T2511	P2514R	2514	Missense	distal	3	no	14.773	12.174	EPSD;PhosphoSitePlus	COSMIC	5.767	Down-regulation
CMGC_CDK_CDK2_CDK3_ST	P46531	NOTCH1	Q00526	CDK3	T2511	P2517L	2517	Missense	distal	6	no	14.773	14.776	EPSD;PhosphoSitePlus	COSMIC	5.767	Up-regulation
CMGC_CDK_CDK2_CDK3_ST	P46531	NOTCH1	Q00526	CDK3	T2511	H2507R	2507	Missense	distal	-4	no	14.773	14.394	EPSD;PhosphoSitePlus	COSMIC	5.767	Down-regulation
CMGC_CDK_CDK2_CDK3_ST	P46531	NOTCH1	Q00526	CDK3	T2511	H2507Y	2507	Missense	distal	-4	no	14.773	14.896	EPSD;PhosphoSitePlus	COSMIC	5.767	Up-regulation
CMGC_CDK_CDK2_CDK3_ST	P46531	NOTCH1	Q00526	CDK3	T2511	F2509S	2509	Missense	proximal	-2	no	14.773	14.511	EPSD;PhosphoSitePlus	COSMIC	5.767	Down-regulation
CMGC_CDK_CDK2_CDK3_ST	P46531	NOTCH1	Q00526	CDK3	T2511	L2510F	2510	Missense	proximal	-1	no	14.773	14.769	EPSD;PhosphoSitePlus	COSMIC	5.767	Down-regulation
CMGC_CDK_CDK2_CDK3_ST	P46531	NOTCH1	Q00526	CDK3	T2511	P2508A	2508	Missense	distal	-3	no	14.773	14.802	EPSD;PhosphoSitePlus	COSMIC	5.767	Up-regulation
CMGC_CDK_CDK2_CDK3_ST	P46531	NOTCH1	Q00526	CDK3	T2511	P2514S	2514	Missense	distal	3	no	14.773	12.611	EPSD;PhosphoSitePlus	COSMIC	5.767	Down-regulation
CMGC_CDK_CDK2_CDK3_ST	P46531	NOTCH1	Q00526	CDK3	T2511	S2516A	2516	Missense	distal	5	no	14.773	14.874	EPSD;PhosphoSitePlus	COSMIC	5.767	Up-regulation
CMGC_CDK_CDK2_CDK3_ST	P46531	NOTCH1	Q00526	CDK3	T2511	L2510R	2510	Missense	proximal	-1	no	14.773	14.771	EPSD;PhosphoSitePlus	COSMIC	5.767	Down-regulation
CMGC_CDK_CDK2_CDK3_ST	P46531	NOTCH1	Q00526	CDK3	T2511	S2513F	2513	Missense	proximal	2	no	14.773	14.624	EPSD;PhosphoSitePlus	COSMIC	5.767	Down-regulation
CMGC_CDK_CDK2_CDK3_ST	P46531	NOTCH1	Q00526	CDK3	T2511	P2514L	2514	Missense	distal	3	no	14.773	12.575	EPSD;PhosphoSitePlus	COSMIC	5.767	Down-regulation
CMGC_CDK_CDK2_CDK3_ST	P46531	NOTCH1	Q00526	CDK3	T2511	E2515K	2515	Missense	distal	4	no	14.773	14.803	EPSD;PhosphoSitePlus	COSMIC	5.767	Up-regulation
CMGC_CDK_CDK2_CDK3_ST	P46531	NOTCH1	Q00526	CDK3	T2511	L2510H	2510	Missense	proximal	-1	no	14.773	14.766	EPSD;PhosphoSitePlus	COSMIC	5.767	Down-regulation
CMGC_CDK_CDK2_CDK3_ST	P46531	NOTCH1	Q00526	CDK3	T2511	E2506K	2506	Missense	distal	-5	no	14.773	14.627	EPSD;PhosphoSitePlus	COSMIC	5.767	Down-regulation
CMGC_CDK_CDK2_CDK3_ST	P46531	NOTCH1	Q00526	CDK3	S2513	P2514R	2514	Missense	proximal	1	no	10.776	4.153	PhosphoSitePlus;EPSD	COSMIC	5.767	Loss
CMGC_CDK_CDK2_CDK3_ST	P46531	NOTCH1	Q00526	CDK3	S2513	P2517L	2517	Missense	distal	4	no	10.776	10.782	PhosphoSitePlus;EPSD	COSMIC	5.767	Up-regulation
CMGC_CDK_CDK2_CDK3_ST	P46531	NOTCH1	Q00526	CDK3	S2513	H2507R	2507	Missense	distal	-6	no	10.776	10.922	PhosphoSitePlus;EPSD	COSMIC	5.767	Up-regulation
CMGC_CDK_CDK2_CDK3_ST	P46531	NOTCH1	Q00526	CDK3	S2513	H2507Y	2507	Missense	distal	-6	no	10.776	10.473	PhosphoSitePlus;EPSD	COSMIC	5.767	Down-regulation
CMGC_CDK_CDK2_CDK3_ST	P46531	NOTCH1	Q00526	CDK3	S2513	F2509S	2509	Missense	distal	-4	no	10.776	12.118	PhosphoSitePlus;EPSD	COSMIC	5.767	Up-regulation
CMGC_CDK_CDK2_CDK3_ST	P46531	NOTCH1	Q00526	CDK3	S2513	L2510F	2510	Missense	distal	-3	no	10.776	10.694	PhosphoSitePlus;EPSD	COSMIC	5.767	Down-regulation
CMGC_CDK_CDK2_CDK3_ST	P46531	NOTCH1	Q00526	CDK3	S2513	P2508A	2508	Missense	distal	-5	no	10.776	10.717	PhosphoSitePlus;EPSD	COSMIC	5.767	Down-regulation
CMGC_CDK_CDK2_CDK3_ST	P46531	NOTCH1	Q00526	CDK3	S2513	P2514S	2514	Missense	proximal	1	no	10.776	5.713	PhosphoSitePlus;EPSD	COSMIC	5.767	Loss
CMGC_CDK_CDK2_CDK3_ST	P46531	NOTCH1	Q00526	CDK3	S2513	S2516A	2516	Missense	distal	3	no	10.776	11.099	PhosphoSitePlus;EPSD	COSMIC	5.767	Up-regulation
CMGC_CDK_CDK2_CDK3_ST	P46531	NOTCH1	Q00526	CDK3	S2513	L2510R	2510	Missense	distal	-3	no	10.776	10.771	PhosphoSitePlus;EPSD	COSMIC	5.767	Down-regulation
CMGC_CDK_CDK2_CDK3_ST	P46531	NOTCH1	Q00526	CDK3	S2513	S2513F	2513	Missense	central	0	yes	10.776	0.000	PhosphoSitePlus;EPSD	COSMIC	5.767	Loss
CMGC_CDK_CDK2_CDK3_ST	P46531	NOTCH1	Q00526	CDK3	S2513	P2514L	2514	Missense	proximal	1	no	10.776	4.032	PhosphoSitePlus;EPSD	COSMIC	5.767	Loss
CMGC_CDK_CDK2_CDK3_ST	P46531	NOTCH1	Q00526	CDK3	S2513	E2515K	2515	Missense	proximal	2	no	10.776	10.652	PhosphoSitePlus;EPSD	COSMIC	5.767	Down-regulation
CMGC_CDK_CDK2_CDK3_ST	P46531	NOTCH1	Q00526	CDK3	S2513	L2510H	2510	Missense	distal	-3	no	10.776	10.683	PhosphoSitePlus;EPSD	COSMIC	5.767	Down-regulation
CMGC_CDK_CDK2_CDK3_ST	P46531	NOTCH1	Q00526	CDK3	S2513	E2506K	2506	Missense	distal	-7	no	10.776	10.680	PhosphoSitePlus;EPSD	COSMIC	5.767	Down-regulation
CMGC_CDK_CDK2_CDK3_ST	P46531	NOTCH1	Q00526	CDK3	S2516	P2514R	2514	Missense	proximal	-2	no	12.861	13.135	EPSD;PhosphoSitePlus	COSMIC	5.767	Up-regulation
CMGC_CDK_CDK2_CDK3_ST	P46531	NOTCH1	Q00526	CDK3	S2516	P2517L	2517	Missense	proximal	1	no	12.861	6.116	EPSD;PhosphoSitePlus	COSMIC	5.767	Down-regulation
CMGC_CDK_CDK2_CDK3_ST	P46531	NOTCH1	Q00526	CDK3	S2516	F2509S	2509	Missense	distal	-7	no	12.861	12.465	EPSD;PhosphoSitePlus	COSMIC	5.767	Down-regulation
CMGC_CDK_CDK2_CDK3_ST	P46531	NOTCH1	Q00526	CDK3	S2516	L2510F	2510	Missense	distal	-6	no	12.861	12.263	EPSD;PhosphoSitePlus	COSMIC	5.767	Down-regulation
CMGC_CDK_CDK2_CDK3_ST	P46531	NOTCH1	Q00526	CDK3	S2516	P2514S	2514	Missense	proximal	-2	no	12.861	12.731	EPSD;PhosphoSitePlus	COSMIC	5.767	Down-regulation
CMGC_CDK_CDK2_CDK3_ST	P46531	NOTCH1	Q00526	CDK3	S2516	S2516A	2516	Missense	central	0	yes	12.861	0.000	EPSD;PhosphoSitePlus	COSMIC	5.767	Loss
CMGC_CDK_CDK2_CDK3_ST	P46531	NOTCH1	Q00526	CDK3	S2516	L2510R	2510	Missense	distal	-6	no	12.861	12.481	EPSD;PhosphoSitePlus	COSMIC	5.767	Down-regulation
CMGC_CDK_CDK2_CDK3_ST	P46531	NOTCH1	Q00526	CDK3	S2516	S2513F	2513	Missense	distal	-3	no	12.861	12.975	EPSD;PhosphoSitePlus	COSMIC	5.767	Up-regulation
CMGC_CDK_CDK2_CDK3_ST	P46531	NOTCH1	Q00526	CDK3	S2516	P2514L	2514	Missense	proximal	-2	no	12.861	13.128	EPSD;PhosphoSitePlus	COSMIC	5.767	Up-regulation
CMGC_CDK_CDK2_CDK3_ST	P46531	NOTCH1	Q00526	CDK3	S2516	E2515K	2515	Missense	proximal	-1	no	12.861	12.857	EPSD;PhosphoSitePlus	COSMIC	5.767	Down-regulation
CMGC_CDK_CDK2_CDK3_ST	P46531	NOTCH1	Q00526	CDK3	S2516	L2510H	2510	Missense	distal	-6	no	12.861	12.336	EPSD;PhosphoSitePlus	COSMIC	5.767	Down-regulation
CMGC_CDK_CDK2_CDK3_ST	P46531	NOTCH1	Q00526	CDK3	S2524	P2517L	2517	Missense	distal	-7	no	5.655	6.146	EPSD	COSMIC	5.767	Gain
CMGC_CDK_CDK2_CDK3_ST	P46531	NOTCH1	Q00526	CDK3	S2524	V2529I	2529	Missense	distal	5	no	5.655	5.924	EPSD	COSMIC	5.767	Gain
CMGC_CDK_CDK2_CDK3_ST	P05412	JUN	Q00526	CDK3	S63	K56N	56	Missense	distal	-7	no	13.865	13.808	EPSD;PhosphoSitePlus	COSMIC	5.767	Down-regulation
CMGC_CDK_CDK2_CDK3_ST	P05412	JUN	Q00526	CDK3	S63	L61F	61	Missense	proximal	-2	no	13.865	13.729	EPSD;PhosphoSitePlus	COSMIC	5.767	Down-regulation
CMGC_CDK_CDK2_CDK3_ST	P05412	JUN	Q00526	CDK3	S73	R78H	78	Missense	distal	5	no	13.846	13.738	PhosphoSitePlus;EPSD	COSMIC	5.767	Down-regulation
CMGC_CDK_CDK2_CDK3_ST	P05412	JUN	Q00526	CDK3	T91	P92Q	92	Missense	proximal	1	no	8.463	2.576	EPSD	COSMIC	5.767	Loss
CMGC_CDK_CDK2_CDK3_ST	P05412	JUN	Q00526	CDK3	T91	L98M	98	Missense	distal	7	no	8.463	8.429	EPSD	COSMIC	5.767	Down-regulation
CMGC_CDK_CDK2_CDK3_ST	P05412	JUN	Q00526	CDK3	T91	P94S	94	Missense	distal	3	no	8.463	6.300	EPSD	COSMIC	5.767	Down-regulation
CMGC_CDK_CDK2_CDK3_ST	P05412	JUN	Q00526	CDK3	T93	P100L	100	Missense	distal	7	no	8.816	8.891	EPSD	COSMIC	5.767	Up-regulation
CMGC_CDK_CDK2_CDK3_ST	P05412	JUN	Q00526	CDK3	T93	P92Q	92	Missense	proximal	-1	no	8.816	8.820	EPSD	COSMIC	5.767	Up-regulation
CMGC_CDK_CDK2_CDK3_ST	P05412	JUN	Q00526	CDK3	T93	L98M	98	Missense	distal	5	no	8.816	8.777	EPSD	COSMIC	5.767	Down-regulation
CMGC_CDK_CDK2_CDK3_ST	P05412	JUN	Q00526	CDK3	T93	P94S	94	Missense	proximal	1	no	8.816	3.753	EPSD	COSMIC	5.767	Loss
CMGC_CDK_CDK2_CDK3_ST	P05412	JUN	Q00526	CDK3	S243	P240Q	240	Missense	distal	-3	no	6.622	6.717	EPSD	COSMIC	5.767	Up-regulation
CMGC_CDK_CDK2_CDK3_ST	P05412	JUN	Q00526	CDK3	S243	T239I	239	Missense	distal	-4	no	6.622	5.785	EPSD	COSMIC	5.767	Down-regulation
CMGC_CDK_CDK2_CDK3_ST	P18846	ATF1	Q00526	CDK3	S63	P62L	62	Missense	proximal	-1	no	14.522	14.537	PhosphoSitePlus	COSMIC;CCLE	5.767	Up-regulation
CMGC_CDK_CDK2_CDK3_ST	P18846	ATF1	Q00526	CDK3	T184	Y179H	179	Missense	distal	-5	no	9.924	10.077	EPSD	COSMIC	5.767	Up-regulation
CMGC_CDK_CDK2_CDK3_ST	P18846	ATF1	Q00526	CDK3	T184	P191A	191	Missense	distal	7	no	9.924	9.969	EPSD	COSMIC	5.767	Up-regulation
CMGC_CDK_CDK2_CDK3_ST	P18846	ATF1	Q00526	CDK3	T184	L190M	190	Missense	distal	6	no	9.924	9.925	EPSD	COSMIC	5.767	Up-regulation
CMGC_CDK_CDK2_CDK3_ST	P18846	ATF1	Q00526	CDK3	T184	P185L	185	Missense	proximal	1	no	9.924	3.179	EPSD	COSMIC	5.767	Loss
CMGC_CDK_CDK2_CDK3_ST	P18846	ATF1	Q00526	CDK3	T184	R182G	182	Missense	proximal	-2	no	9.924	9.897	EPSD	COSMIC;GDSC;CCLE	5.767	Down-regulation
CMGC_CDK_CDK2_CDK3_ST	P18846	ATF1	Q00526	CDK3	S198	P191A	191	Missense	distal	-7	no	6.532	6.779	EPSD	COSMIC	5.767	Up-regulation
CMGC_CDK_CDK2_CDK3_ST	P18846	ATF1	Q00526	CDK3	S198	Q205R	205	Missense	distal	7	no	6.532	6.550	EPSD	COSMIC	5.767	Up-regulation
CMGC_CDK_CDK2_CDK3_ST	P18846	ATF1	Q00526	CDK3	S198	P199L	199	Missense	proximal	1	no	6.532	-0.213	EPSD	COSMIC	5.767	Loss
CMGC_CDK_CDK2_CDK3_ST	Q12800	TFCP2	Q00526	CDK3	S54	E53Q	53	Missense	proximal	-1	no	6.933	6.929	EPSD	COSMIC	5.767	Down-regulation
CMGC_CDK_CDK2_CDK3_ST	Q12800	TFCP2	Q00526	CDK3	S54	E61K	61	Missense	distal	7	no	6.933	6.904	EPSD	COSMIC	5.767	Down-regulation
CMGC_CDK_CDK2_CDK3_ST	Q12800	TFCP2	Q00526	CDK3	S54	S55N	55	Missense	proximal	1	no	6.933	5.753	EPSD	COSMIC	5.767	Loss
CMGC_CDK_CDK2_CDK3_ST	Q12800	TFCP2	Q00526	CDK3	T197	H190R	190	Missense	distal	-7	no	5.546	5.768	EPSD	COSMIC;CCLE	5.767	Gain
CMGC_CDK_CDK2_CDK3_ST	Q12800	TFCP2	Q00526	CDK3	T258	E263K	263	Missense	distal	5	no	9.058	8.900	EPSD	COSMIC	5.767	Down-regulation
CMGC_CDK_CDK2_CDK3_ST	Q12800	TFCP2	Q00526	CDK3	T258	R257L	257	Missense	proximal	-1	no	9.058	9.060	EPSD	COSMIC	5.767	Up-regulation
CMGC_CDK_CDK2_CDK3_ST	Q12800	TFCP2	Q00526	CDK3	T258	E252K	252	Missense	distal	-6	no	9.058	8.887	EPSD	COSMIC	5.767	Down-regulation
CMGC_CDK_CDK2_CDK3_ST	Q12800	TFCP2	Q00526	CDK3	S289	N295I	295	Missense	distal	6	no	10.601	10.651	EPSD	COSMIC	5.767	Up-regulation
CMGC_CDK_CDK2_CDK3_ST	Q12800	TFCP2	Q00526	CDK3	S291	N295I	295	Missense	distal	4	no	8.309	8.219	EPSD	COSMIC	5.767	Down-regulation
CMGC_CDK_CDK2_CDK3_ST	Q12800	TFCP2	Q00526	CDK3	S309	G306V	306	Missense	distal	-3	no	14.086	13.890	PhosphoSitePlus	COSMIC	5.767	Down-regulation
CMGC_CDK_CDK2_CDK3_ST	Q12800	TFCP2	Q00526	CDK3	S309	P314L	314	Missense	distal	5	no	14.086	14.426	PhosphoSitePlus	COSMIC;GDSC;CCLE	5.767	Up-regulation
CMGC_CDK_CDK2_CDK3_ST	Q8TDN4	CABLES1	Q00526	CDK3	S168	G173C	173	Missense	distal	5	no	5.803	5.712	EPSD	COSMIC;CCLE	5.767	Loss
CMGC_CDK_CDK2_CDK3_ST	Q8TDN4	CABLES1	Q00526	CDK3	S168	G171D	171	Missense	distal	3	no	5.803	6.349	EPSD	COSMIC	5.767	Up-regulation
CMGC_CDK_CDK2_CDK3_ST	Q8TDN4	CABLES1	Q00526	CDK3	S291	R284C	284	Missense	distal	-7	no	6.075	5.924	EPSD	COSMIC	5.767	Down-regulation
CMGC_CDK_CDK2_CDK3_ST	Q8TDN4	CABLES1	Q00526	CDK3	S291	L295M	295	Missense	distal	4	no	6.075	6.096	EPSD	COSMIC	5.767	Up-regulation
CMGC_CDK_CDK2_CDK3_ST	Q8TDN4	CABLES1	Q00526	CDK3	S291	R284H	284	Missense	distal	-7	no	6.075	5.854	EPSD	COSMIC	5.767	Down-regulation
CMGC_CDK_CDK2_CDK3_ST	Q8TDN4	CABLES1	Q00526	CDK3	S313	R308Q	308	Missense	distal	-5	no	15.982	15.477	PhosphoSitePlus	COSMIC	5.767	Down-regulation
CMGC_CDK_CDK2_CDK3_ST	Q8TDN4	CABLES1	Q00526	CDK3	S313	P314S	314	Missense	proximal	1	no	15.982	10.918	PhosphoSitePlus	COSMIC	5.767	Down-regulation
CMGC_CDK_CDK2_CDK3_ST	Q8TDN4	CABLES1	Q00526	CDK3	S313	K317R	317	Missense	distal	4	no	15.982	15.878	PhosphoSitePlus	COSMIC	5.767	Down-regulation
CMGC_CDK_CDK2_CDK3_ST	P06400	RB1	Q00526	CDK3	T52	E53K	53	Missense	proximal	1	no	5.424	7.071	EPSD	COSMIC	5.767	Gain
CMGC_CDK_CDK2_CDK3_ST	P06400	RB1	Q00526	CDK3	S230	K228R	228	Missense	proximal	-2	no	7.509	7.685	EPSD	COSMIC;GDSC;CCLE	5.767	Up-regulation
CMGC_CDK_CDK2_CDK3_ST	P06400	RB1	Q00526	CDK3	S230	I227N	227	Missense	distal	-3	no	7.509	7.399	EPSD	COSMIC	5.767	Down-regulation
CMGC_CDK_CDK2_CDK3_ST	P06400	RB1	Q00526	CDK3	S230	P232L	232	Missense	proximal	2	no	7.509	7.596	EPSD	COSMIC	5.767	Up-regulation
CMGC_CDK_CDK2_CDK3_ST	P06400	RB1	Q00526	CDK3	S249	V243A	243	Missense	distal	-6	no	9.420	9.465	EPSD	COSMIC	5.767	Up-regulation
CMGC_CDK_CDK2_CDK3_ST	P06400	RB1	Q00526	CDK3	S249	P250S	250	Missense	proximal	1	no	9.420	4.356	EPSD	COSMIC	5.767	Loss
CMGC_CDK_CDK2_CDK3_ST	P06400	RB1	Q00526	CDK3	T252	Q257R	257	Missense	distal	5	no	6.845	7.029	EPSD	COSMIC	5.767	Up-regulation
CMGC_CDK_CDK2_CDK3_ST	P06400	RB1	Q00526	CDK3	T252	P250S	250	Missense	proximal	-2	no	6.845	6.715	EPSD	COSMIC	5.767	Down-regulation
CMGC_CDK_CDK2_CDK3_ST	P06400	RB1	Q00526	CDK3	T373	P370S	370	Missense	distal	-3	no	6.520	6.558	EPSD	COSMIC	5.767	Up-regulation
CMGC_CDK_CDK2_CDK3_ST	P06400	RB1	Q00526	CDK3	T373	P374L	374	Missense	proximal	1	no	6.520	-0.225	EPSD	COSMIC	5.767	Loss
CMGC_CDK_CDK2_CDK3_ST	P06400	RB1	Q00526	CDK3	T373	N367D	367	Missense	distal	-6	no	6.520	6.293	EPSD	COSMIC	5.767	Down-regulation
CMGC_CDK_CDK2_CDK3_ST	P06400	RB1	Q00526	CDK3	T373	P370L	370	Missense	distal	-3	no	6.520	6.755	EPSD	COSMIC	5.767	Up-regulation
CMGC_CDK_CDK2_CDK3_ST	P06400	RB1	Q00526	CDK3	S414	K412N	412	Missense	proximal	-2	no	5.918	5.854	EPSD	COSMIC	5.767	Down-regulation
CMGC_CDK_CDK2_CDK3_ST	P06400	RB1	Q00526	CDK3	S414	D421N	421	Missense	distal	7	no	5.918	5.922	EPSD	COSMIC;GDSC;CCLE	5.767	Up-regulation
CMGC_CDK_CDK2_CDK3_ST	P06400	RB1	Q00526	CDK3	S567	W563C	563	Missense	distal	-4	no	7.495	7.490	EPSD	COSMIC	5.767	Down-regulation
CMGC_CDK_CDK2_CDK3_ST	P06400	RB1	Q00526	CDK3	S567	S560P	560	Missense	distal	-7	no	7.495	7.481	EPSD	COSMIC	5.767	Down-regulation
CMGC_CDK_CDK2_CDK3_ST	P06400	RB1	Q00526	CDK3	S567	L564V	564	Missense	distal	-3	no	7.495	7.315	EPSD	COSMIC	5.767	Down-regulation
CMGC_CDK_CDK2_CDK3_ST	P06400	RB1	Q00526	CDK3	S567	L572F	572	Missense	distal	5	no	7.495	7.418	EPSD	COSMIC	5.767	Down-regulation
CMGC_CDK_CDK2_CDK3_ST	P06400	RB1	Q00526	CDK3	S608	R611S	611	Missense	distal	3	no	6.784	7.221	EPSD	COSMIC	5.767	Up-regulation
CMGC_CDK_CDK2_CDK3_ST	P06400	RB1	Q00526	CDK3	S608	S612P	612	Missense	distal	4	no	6.784	6.689	EPSD	COSMIC	5.767	Down-regulation
CMGC_CDK_CDK2_CDK3_ST	P06400	RB1	Q00526	CDK3	S608	Y606C	606	Missense	proximal	-2	no	6.784	6.834	EPSD	COSMIC	5.767	Up-regulation
CMGC_CDK_CDK2_CDK3_ST	P06400	RB1	Q00526	CDK3	S608	P609S	609	Missense	proximal	1	no	6.784	1.720	EPSD	COSMIC	5.767	Loss
CMGC_CDK_CDK2_CDK3_ST	P06400	RB1	Q00526	CDK3	S608	M605T	605	Missense	distal	-3	no	6.784	6.776	EPSD	COSMIC	5.767	Down-regulation
CMGC_CDK_CDK2_CDK3_ST	P06400	RB1	Q00526	CDK3	S608	L607V	607	Missense	proximal	-1	no	6.784	6.771	EPSD	COSMIC	5.767	Down-regulation
CMGC_CDK_CDK2_CDK3_ST	P06400	RB1	Q00526	CDK3	S608	L607I	607	Missense	proximal	-1	no	6.784	6.780	EPSD	COSMIC	5.767	Down-regulation
CMGC_CDK_CDK2_CDK3_ST	P06400	RB1	Q00526	CDK3	S612	R611S	611	Missense	proximal	-1	no	10.432	10.414	EPSD	COSMIC	5.767	Down-regulation
CMGC_CDK_CDK2_CDK3_ST	P06400	RB1	Q00526	CDK3	S612	S612P	612	Missense	central	0	yes	10.432	0.000	EPSD	COSMIC	5.767	Loss
CMGC_CDK_CDK2_CDK3_ST	P06400	RB1	Q00526	CDK3	S612	Y606C	606	Missense	distal	-6	no	10.432	10.720	EPSD	COSMIC	5.767	Up-regulation
CMGC_CDK_CDK2_CDK3_ST	P06400	RB1	Q00526	CDK3	S612	P609S	609	Missense	distal	-3	no	10.432	10.470	EPSD	COSMIC	5.767	Up-regulation
CMGC_CDK_CDK2_CDK3_ST	P06400	RB1	Q00526	CDK3	S612	M605T	605	Missense	distal	-7	no	10.432	10.383	EPSD	COSMIC	5.767	Down-regulation
CMGC_CDK_CDK2_CDK3_ST	P06400	RB1	Q00526	CDK3	S612	L607V	607	Missense	distal	-5	no	10.432	9.359	EPSD	COSMIC	5.767	Down-regulation
CMGC_CDK_CDK2_CDK3_ST	P06400	RB1	Q00526	CDK3	S612	L607I	607	Missense	distal	-5	no	10.432	9.990	EPSD	COSMIC	5.767	Down-regulation
CMGC_CDK_CDK2_CDK3_ST	P06400	RB1	Q00526	CDK3	T620	R621P	621	Missense	proximal	1	no	1.949	8.573	EPSD	COSMIC	5.767	Gain
CMGC_CDK_CDK2_CDK3_ST	P06400	RB1	Q00526	CDK3	S624	Q631K	631	Missense	distal	7	no	6.737	6.711	EPSD	COSMIC	5.767	Down-regulation
CMGC_CDK_CDK2_CDK3_ST	P06400	RB1	Q00526	CDK3	S624	T620M	620	Missense	distal	-4	no	6.737	5.997	EPSD	COSMIC	5.767	Down-regulation
CMGC_CDK_CDK2_CDK3_ST	P06400	RB1	Q00526	CDK3	S624	A626G	626	Missense	proximal	2	no	6.737	6.575	EPSD	COSMIC	5.767	Down-regulation
CMGC_CDK_CDK2_CDK3_ST	P06400	RB1	Q00526	CDK3	S624	E629K	629	Missense	distal	5	no	6.737	6.579	EPSD	COSMIC	5.767	Down-regulation
CMGC_CDK_CDK2_CDK3_ST	P06400	RB1	Q00526	CDK3	S624	R621C	621	Missense	distal	-3	no	6.737	6.661	EPSD	COSMIC	5.767	Down-regulation
CMGC_CDK_CDK2_CDK3_ST	P06400	RB1	Q00526	CDK3	S624	R621S	621	Missense	distal	-3	no	6.737	6.547	EPSD	COSMIC;GDSC	5.767	Down-regulation
CMGC_CDK_CDK2_CDK3_ST	P06400	RB1	Q00526	CDK3	S624	T625A	625	Missense	proximal	1	no	6.737	7.536	EPSD	COSMIC	5.767	Up-regulation
CMGC_CDK_CDK2_CDK3_ST	P06400	RB1	Q00526	CDK3	S624	R621P	621	Missense	distal	-3	no	6.737	6.508	EPSD	COSMIC	5.767	Down-regulation
CMGC_CDK_CDK2_CDK3_ST	P06400	RB1	Q00526	CDK3	S773	T766I	766	Missense	distal	-7	no	7.191	7.433	EPSD	COSMIC	5.767	Up-regulation
CMGC_CDK_CDK2_CDK3_ST	P06400	RB1	Q00526	CDK3	S773	P776R	776	Missense	distal	3	no	7.191	4.592	EPSD	COSMIC	5.767	Loss
CMGC_CDK_CDK2_CDK3_ST	P06400	RB1	Q00526	CDK3	S773	A772S	772	Missense	proximal	-1	no	7.191	7.185	EPSD	COSMIC	5.767	Down-regulation
CMGC_CDK_CDK2_CDK3_ST	P06400	RB1	Q00526	CDK3	S773	P777S	777	Missense	distal	4	no	7.191	7.286	EPSD	COSMIC	5.767	Up-regulation
CMGC_CDK_CDK2_CDK3_ST	P06400	RB1	Q00526	CDK3	S773	I768F	768	Missense	distal	-5	no	7.191	6.907	EPSD	COSMIC	5.767	Down-regulation
CMGC_CDK_CDK2_CDK3_ST	P06400	RB1	Q00526	CDK3	S773	S773F	773	Missense	central	0	yes	7.191	0.000	EPSD	COSMIC	5.767	Loss
CMGC_CDK_CDK2_CDK3_ST	P06400	RB1	Q00526	CDK3	T774	P776R	776	Missense	proximal	2	no	5.729	6.016	EPSD	COSMIC	5.767	Gain
CMGC_CDK_CDK2_CDK3_ST	P06400	RB1	Q00526	CDK3	S780	P776R	776	Missense	distal	-4	no	9.001	8.027	EPSD	COSMIC	5.767	Down-regulation
CMGC_CDK_CDK2_CDK3_ST	P06400	RB1	Q00526	CDK3	S780	H784Y	784	Missense	distal	4	no	9.001	8.939	EPSD	COSMIC	5.767	Down-regulation
CMGC_CDK_CDK2_CDK3_ST	P06400	RB1	Q00526	CDK3	S780	P777S	777	Missense	distal	-3	no	9.001	9.040	EPSD	COSMIC	5.767	Up-regulation
CMGC_CDK_CDK2_CDK3_ST	P06400	RB1	Q00526	CDK3	S780	P786S	786	Missense	distal	6	no	9.001	8.965	EPSD	COSMIC	5.767	Down-regulation
CMGC_CDK_CDK2_CDK3_ST	P06400	RB1	Q00526	CDK3	S780	S773F	773	Missense	distal	-7	no	9.001	9.397	EPSD	COSMIC	5.767	Up-regulation
CMGC_CDK_CDK2_CDK3_ST	P06400	RB1	Q00526	CDK3	S788	S795L	795	Missense	distal	7	no	7.305	7.330	EPSD	COSMIC	5.767	Up-regulation
CMGC_CDK_CDK2_CDK3_ST	P06400	RB1	Q00526	CDK3	S788	H784Y	784	Missense	distal	-4	no	7.305	7.428	EPSD	COSMIC	5.767	Up-regulation
CMGC_CDK_CDK2_CDK3_ST	P06400	RB1	Q00526	CDK3	S788	S794I	794	Missense	distal	6	no	7.305	7.407	EPSD	COSMIC	5.767	Up-regulation
CMGC_CDK_CDK2_CDK3_ST	P06400	RB1	Q00526	CDK3	S788	P786S	786	Missense	proximal	-2	no	7.305	7.175	EPSD	COSMIC	5.767	Down-regulation
CMGC_CDK_CDK2_CDK3_ST	P06400	RB1	Q00526	CDK3	S788	P793S	793	Missense	distal	5	no	7.305	7.252	EPSD	COSMIC;CCLE	5.767	Down-regulation
CMGC_CDK_CDK2_CDK3_ST	P06400	RB1	Q00526	CDK3	S795	S795L	795	Missense	central	0	yes	7.086	0.000	EPSD	COSMIC	5.767	Loss
CMGC_CDK_CDK2_CDK3_ST	P06400	RB1	Q00526	CDK3	S795	G802R	802	Missense	distal	7	no	7.086	7.101	EPSD	COSMIC	5.767	Up-regulation
CMGC_CDK_CDK2_CDK3_ST	P06400	RB1	Q00526	CDK3	S795	R798Q	798	Missense	distal	3	no	7.086	7.457	EPSD	COSMIC;GDSC;CCLE	5.767	Up-regulation
CMGC_CDK_CDK2_CDK3_ST	P06400	RB1	Q00526	CDK3	S795	S794I	794	Missense	proximal	-1	no	7.086	7.101	EPSD	COSMIC	5.767	Up-regulation
CMGC_CDK_CDK2_CDK3_ST	P06400	RB1	Q00526	CDK3	S795	G801A	801	Missense	distal	6	no	7.086	6.971	EPSD	COSMIC	5.767	Down-regulation
CMGC_CDK_CDK2_CDK3_ST	P06400	RB1	Q00526	CDK3	S795	P793S	793	Missense	proximal	-2	no	7.086	6.956	EPSD	COSMIC;CCLE	5.767	Down-regulation
CMGC_CDK_CDK2_CDK3_ST	P06400	RB1	Q00526	CDK3	S807	G802R	802	Missense	distal	-5	no	13.237	13.583	PhosphoSitePlus;EPSD	COSMIC	5.767	Up-regulation
CMGC_CDK_CDK2_CDK3_ST	P06400	RB1	Q00526	CDK3	S807	K814T	814	Missense	distal	7	no	13.237	13.277	PhosphoSitePlus;EPSD	COSMIC	5.767	Up-regulation
CMGC_CDK_CDK2_CDK3_ST	P06400	RB1	Q00526	CDK3	S807	G801A	801	Missense	distal	-6	no	13.237	12.697	PhosphoSitePlus;EPSD	COSMIC	5.767	Down-regulation
CMGC_CDK_CDK2_CDK3_ST	P06400	RB1	Q00526	CDK3	S811	G818S	818	Missense	distal	7	no	14.389	14.376	EPSD;PhosphoSitePlus	COSMIC	5.767	Down-regulation
CMGC_CDK_CDK2_CDK3_ST	P06400	RB1	Q00526	CDK3	S811	G818C	818	Missense	distal	7	no	14.389	14.404	EPSD;PhosphoSitePlus	COSMIC	5.767	Up-regulation
CMGC_CDK_CDK2_CDK3_ST	P06400	RB1	Q00526	CDK3	S811	K814T	814	Missense	distal	3	no	14.389	13.125	EPSD;PhosphoSitePlus	COSMIC	5.767	Down-regulation
CMGC_CDK_CDK2_CDK3_ST	P06400	RB1	Q00526	CDK3	T821	G818S	818	Missense	distal	-3	no	6.209	5.997	EPSD	COSMIC	5.767	Down-regulation
CMGC_CDK_CDK2_CDK3_ST	P06400	RB1	Q00526	CDK3	T821	P822S	822	Missense	proximal	1	no	6.209	1.145	EPSD	COSMIC	5.767	Loss
CMGC_CDK_CDK2_CDK3_ST	P06400	RB1	Q00526	CDK3	T821	G818C	818	Missense	distal	-3	no	6.209	6.112	EPSD	COSMIC	5.767	Down-regulation
CMGC_CDK_CDK2_CDK3_ST	P06400	RB1	Q00526	CDK3	T821	K814T	814	Missense	distal	-7	no	6.209	6.253	EPSD	COSMIC	5.767	Up-regulation
CMGC_CDK_CDK2_CDK3_ST	P06400	RB1	Q00526	CDK3	T826	S829L	829	Missense	distal	3	no	8.468	8.432	EPSD	COSMIC	5.767	Down-regulation
CMGC_CDK_CDK2_CDK3_ST	P06400	RB1	Q00526	CDK3	T826	P822S	822	Missense	distal	-4	no	8.468	9.188	EPSD	COSMIC	5.767	Up-regulation
CMGC_CDK_CDK2_CDK3_ST	P06400	RB1	Q00526	CDK3	S838	G840V	840	Missense	proximal	2	no	5.563	5.778	EPSD	COSMIC	5.767	Gain
CMGC_CDK_CDK2_CDK3_ST	P06400	RB1	Q00526	CDK3	S866	L859F	859	Missense	distal	-7	no	6.000	5.919	EPSD	COSMIC	5.767	Down-regulation
CMGC_CDK_CDK2_CDK3_ST	P06400	RB1	Q00526	CDK3	S866	K873T	873	Missense	distal	7	no	6.000	6.040	EPSD	COSMIC	5.767	Up-regulation
Other_WNK_WNK2_ST	Q9UEW8	STK39	Q9Y3S1	WNK2	T224	G220R	220	Missense	distal	-4	no	2.550	2.506	EPSD	COSMIC	2.413	Down-regulation
Other_WNK_WNK2_ST	Q9UEW8	STK39	Q9Y3S1	WNK2	T224	T224A	224	Missense	central	0	yes	2.550	0.000	EPSD	COSMIC	2.413	Loss
Other_WNK_WNK2_ST	Q9UEW8	STK39	Q9Y3S1	WNK2	T224	R229K	229	Missense	distal	5	no	2.550	2.624	EPSD	COSMIC	2.413	Up-regulation
Other_WNK_WNK2_ST	Q9UEW8	STK39	Q9Y3S1	WNK2	T224	A218V	218	Missense	distal	-6	no	2.550	2.290	EPSD	COSMIC	2.413	Loss
Other_WNK_WNK2_ST	Q9UEW8	STK39	Q9Y3S1	WNK2	S371	E378K	378	Missense	distal	7	no	7.282	7.449	EPSD;PhosphoSitePlus	COSMIC;GDSC;CCLE	2.413	Up-regulation
Other_WNK_WNK2_ST	Q9UEW8	STK39	Q9Y3S1	WNK2	S385	D381Y	381	Missense	distal	-4	no	2.490	2.496	EPSD	COSMIC	2.413	Up-regulation
Other_WNK_WNK2_ST	Q9UEW8	STK39	Q9Y3S1	WNK2	S385	E378K	378	Missense	distal	-7	no	2.490	2.552	EPSD	COSMIC;GDSC;CCLE	2.413	Up-regulation
Other_WNK_WNK2_ST	Q9UEW8	STK39	Q9Y3S1	WNK2	S385	E391A	391	Missense	distal	6	no	2.490	2.257	EPSD	COSMIC	2.413	Loss
Other_WNK_WNK2_ST	Q9H4A3	WNK1	Q9Y3S1	WNK2	S215	G218E	218	Missense	distal	3	no	2.304	2.455	EPSD	COSMIC	2.413	Gain
Other_WNK_WNK2_ST	Q9H4A3	WNK1	Q9Y3S1	WNK2	S382	S378P	378	Missense	distal	-4	no	8.337	8.360	PhosphoSitePlus	COSMIC	2.413	Up-regulation
Other_WNK_WNK2_ST	Q9H4A3	WNK1	Q9Y3S1	WNK2	S597	I603T	603	Missense	distal	6	no	2.940	3.039	EPSD	COSMIC	2.413	Up-regulation
Other_WNK_WNK2_ST	Q9H4A3	WNK1	Q9Y3S1	WNK2	T1115	S1110C	1110	Missense	distal	-5	no	2.453	2.457	EPSD	COSMIC	2.413	Up-regulation
Other_WNK_WNK2_ST	Q9H4A3	WNK1	Q9Y3S1	WNK2	T1115	H1112Y	1112	Missense	distal	-3	no	2.453	2.442	EPSD	COSMIC;GDSC;CCLE	2.413	Down-regulation
Other_WNK_WNK2_ST	Q9H4A3	WNK1	Q9Y3S1	WNK2	T1115	R1121S	1121	Missense	distal	6	no	2.453	2.079	EPSD	COSMIC	2.413	Loss
Other_WNK_WNK2_ST	Q9H4A3	WNK1	Q9Y3S1	WNK2	S1193	S1197N	1197	Missense	distal	4	no	2.683	2.681	EPSD	COSMIC	2.413	Down-regulation
Other_WNK_WNK2_ST	Q9H4A3	WNK1	Q9Y3S1	WNK2	S1193	S1197T	1197	Missense	distal	4	no	2.683	2.666	EPSD	COSMIC	2.413	Down-regulation
Other_WNK_WNK2_ST	Q9H4A3	WNK1	Q9Y3S1	WNK2	S1193	S1193N	1193	Missense	central	0	yes	2.683	0.000	EPSD	COSMIC	2.413	Loss
Other_WNK_WNK2_ST	Q9H4A3	WNK1	Q9Y3S1	WNK2	S1193	V1196F	1196	Missense	distal	3	no	2.683	2.743	EPSD	COSMIC	2.413	Up-regulation
Other_WNK_WNK2_ST	Q9H4A3	WNK1	Q9Y3S1	WNK2	S1193	E1199G	1199	Missense	distal	6	no	2.683	2.434	EPSD	COSMIC	2.413	Down-regulation
Other_WNK_WNK2_ST	Q9H4A3	WNK1	Q9Y3S1	WNK2	S1193	E1199K	1199	Missense	distal	6	no	2.683	2.436	EPSD	COSMIC	2.413	Down-regulation
Other_WNK_WNK2_ST	Q9H4A3	WNK1	Q9Y3S1	WNK2	S1246	S1246C	1246	Missense	central	0	yes	3.354	0.000	EPSD	COSMIC	2.413	Loss
Other_WNK_WNK2_ST	Q9H4A3	WNK1	Q9Y3S1	WNK2	S1246	P1243Q	1243	Missense	distal	-3	no	3.354	3.305	EPSD	COSMIC	2.413	Down-regulation
Other_WNK_WNK2_ST	Q9H4A3	WNK1	Q9Y3S1	WNK2	S1246	P1243L	1243	Missense	distal	-3	no	3.354	3.284	EPSD	COSMIC	2.413	Down-regulation
Other_WNK_WNK2_ST	Q9H4A3	WNK1	Q9Y3S1	WNK2	S1246	Q1249E	1249	Missense	distal	3	no	3.354	3.613	EPSD	COSMIC	2.413	Up-regulation
Other_WNK_WNK2_ST	Q9H4A3	WNK1	Q9Y3S1	WNK2	S1805	Q1799E	1799	Missense	distal	-6	no	2.113	3.255	EPSD	COSMIC;GDSC;CCLE	2.413	Gain
Other_WNK_WNK2_ST	Q9H4A3	WNK1	Q9Y3S1	WNK2	T1848	V1854A	1854	Missense	distal	6	no	2.778	2.790	EPSD	COSMIC	2.413	Up-regulation
Other_WNK_WNK2_ST	Q9H4A3	WNK1	Q9Y3S1	WNK2	T1848	S1849N	1849	Missense	proximal	1	no	2.778	2.939	EPSD	COSMIC	2.413	Up-regulation
Other_WNK_WNK2_ST	Q9H4A3	WNK1	Q9Y3S1	WNK2	S1961	K1966E	1966	Missense	distal	5	no	2.786	2.736	EPSD	COSMIC	2.413	Down-regulation
Other_WNK_WNK2_ST	Q9H4A3	WNK1	Q9Y3S1	WNK2	S1961	G1956S	1956	Missense	distal	-5	no	2.786	2.892	EPSD	COSMIC	2.413	Up-regulation
Other_WNK_WNK2_ST	Q9H4A3	WNK1	Q9Y3S1	WNK2	T1963	K1966E	1966	Missense	distal	3	no	2.354	2.631	EPSD	COSMIC	2.413	Gain
Other_WNK_WNK2_ST	Q9H4A3	WNK1	Q9Y3S1	WNK2	T1963	G1956S	1956	Missense	distal	-7	no	2.354	2.511	EPSD	COSMIC	2.413	Gain
Other_WNK_WNK2_ST	Q9H4A3	WNK1	Q9Y3S1	WNK2	S2032	S2027N	2027	Missense	distal	-5	no	2.474	2.414	EPSD	COSMIC	2.413	Down-regulation
Other_WNK_WNK2_ST	Q9H4A3	WNK1	Q9Y3S1	WNK2	S2056	S2061T	2061	Missense	distal	5	no	2.712	2.577	EPSD	COSMIC	2.413	Down-regulation
Other_WNK_WNK2_ST	Q9H4A3	WNK1	Q9Y3S1	WNK2	T2128	K2134R	2134	Missense	distal	6	no	2.159	2.485	EPSD	COSMIC	2.413	Gain
Other_WNK_WNK2_ST	Q9H4A3	WNK1	Q9Y3S1	WNK2	S2145	P2146H	2146	Missense	proximal	1	no	2.643	2.520	EPSD	COSMIC	2.413	Down-regulation
Other_WNK_WNK2_ST	Q9H4A3	WNK1	Q9Y3S1	WNK2	S2145	K2144E	2144	Missense	proximal	-1	no	2.643	2.509	EPSD	COSMIC;GDSC;CCLE	2.413	Down-regulation
Other_WNK_WNK2_ST	Q9H4A3	WNK1	Q9Y3S1	WNK2	S2145	G2150A	2150	Missense	distal	5	no	2.643	2.687	EPSD	COSMIC	2.413	Up-regulation
Other_WNK_WNK2_ST	Q9H4A3	WNK1	Q9Y3S1	WNK2	S2302	S2309T	2309	Missense	distal	7	no	2.393	2.416	EPSD	COSMIC;GDSC;CCLE	2.413	Gain
TK_Trk_NTRK2_Y	Q16620	NTRK2	Q16620	NTRK2	Y558	Y558S	558	Missense	central	0	yes	0.000	0.000	EPSD	COSMIC	0.000	Loss
TK_Trk_NTRK2_Y	P22001	KCNA3	Q16620	NTRK2	Y499	Y499H	499	Missense	central	0	yes	0.000	0.000	EPSD;PhosphoSitePlus	COSMIC	0.000	Loss
AGC_RSK_MSK_RPS6KA4_ST	P16220	CREB1	O75676	RPS6KA4	S98	S103N	103	Missense	distal	5	no	2.588	2.480	EPSD	COSMIC	2.457	Down-regulation
AGC_RSK_MSK_RPS6KA4_ST	P16220	CREB1	O75676	RPS6KA4	S98	R95I	95	Missense	distal	-3	no	2.588	1.169	EPSD	COSMIC	2.457	Loss
AGC_RSK_MSK_RPS6KA4_ST	P16220	CREB1	O75676	RPS6KA4	S98	I102M	102	Missense	distal	4	no	2.588	2.531	EPSD	COSMIC	2.457	Down-regulation
AGC_RSK_MSK_RPS6KA4_ST	P16220	CREB1	O75676	RPS6KA4	S103	S103N	103	Missense	central	0	yes	2.746	0.000	EPSD	COSMIC	2.457	Loss
AGC_RSK_MSK_RPS6KA4_ST	P16220	CREB1	O75676	RPS6KA4	S103	E109K	109	Missense	distal	6	no	2.746	2.576	EPSD	COSMIC	2.457	Down-regulation
AGC_RSK_MSK_RPS6KA4_ST	P16220	CREB1	O75676	RPS6KA4	S103	I102M	102	Missense	proximal	-1	no	2.746	2.687	EPSD	COSMIC	2.457	Down-regulation
AGC_RSK_MSK_RPS6KA4_ST	P16220	CREB1	O75676	RPS6KA4	S133	L128R	128	Missense	distal	-5	no	9.316	9.221	PhosphoSitePlus	COSMIC	2.457	Down-regulation
AGC_RSK_MSK_RPS6KA4_ST	P16220	CREB1	O75676	RPS6KA4	S271	A269T	269	Missense	proximal	-2	no	1.813	2.636	EPSD	COSMIC	2.457	Gain
AGC_RSK_MSK_RPS6KA4_ST	P54253	ATXN1	O75676	RPS6KA4	S25	R24P	24	Missense	proximal	-1	no	2.589	2.587	EPSD	COSMIC	2.457	Down-regulation
AGC_RSK_MSK_RPS6KA4_ST	P54253	ATXN1	O75676	RPS6KA4	S25	A30S	30	Missense	distal	5	no	2.589	2.597	EPSD	COSMIC	2.457	Up-regulation
AGC_RSK_MSK_RPS6KA4_ST	P54253	ATXN1	O75676	RPS6KA4	S25	S26F	26	Missense	proximal	1	no	2.589	2.655	EPSD	COSMIC	2.457	Up-regulation
AGC_RSK_MSK_RPS6KA4_ST	P54253	ATXN1	O75676	RPS6KA4	S26	R24P	24	Missense	proximal	-2	no	3.629	1.251	EPSD	COSMIC	2.457	Loss
AGC_RSK_MSK_RPS6KA4_ST	P54253	ATXN1	O75676	RPS6KA4	S26	A30S	30	Missense	distal	4	no	3.629	3.602	EPSD	COSMIC	2.457	Down-regulation
AGC_RSK_MSK_RPS6KA4_ST	P54253	ATXN1	O75676	RPS6KA4	S26	S26F	26	Missense	central	0	yes	3.629	0.000	EPSD	COSMIC	2.457	Loss
AGC_RSK_MSK_RPS6KA4_ST	P54253	ATXN1	O75676	RPS6KA4	S262	G258C	258	Missense	distal	-4	no	3.049	3.048	EPSD	COSMIC	2.457	Down-regulation
AGC_RSK_MSK_RPS6KA4_ST	Q04206	RELA	O75676	RPS6KA4	S261	R267C	267	Missense	distal	6	no	2.924	3.037	EPSD	COSMIC	2.457	Up-regulation
AGC_RSK_MSK_RPS6KA4_ST	Q04206	RELA	O75676	RPS6KA4	S261	P256H	256	Missense	distal	-5	no	2.924	2.978	EPSD	COSMIC	2.457	Up-regulation
AGC_RSK_MSK_RPS6KA4_ST	Q04206	RELA	O75676	RPS6KA4	S269	R267C	267	Missense	proximal	-2	no	2.721	0.584	EPSD	COSMIC	2.457	Loss
AGC_RSK_MSK_RPS6KA4_ST	Q04206	RELA	O75676	RPS6KA4	S269	R274Q	274	Missense	distal	5	no	2.721	2.732	EPSD	COSMIC	2.457	Up-regulation
AGC_RSK_MSK_RPS6KA4_ST	Q04206	RELA	O75676	RPS6KA4	S276	D277N	277	Missense	proximal	1	no	9.456	9.419	PhosphoSitePlus	COSMIC;CCLE	2.457	Down-regulation
AGC_RSK_MSK_RPS6KA4_ST	Q04206	RELA	O75676	RPS6KA4	S276	R274Q	274	Missense	proximal	-2	no	9.456	6.957	PhosphoSitePlus	COSMIC	2.457	Down-regulation
AGC_RSK_MSK_RPS6KA4_ST	Q04206	RELA	O75676	RPS6KA4	S276	R278Q	278	Missense	proximal	2	no	9.456	9.408	PhosphoSitePlus	COSMIC	2.457	Down-regulation
AGC_RSK_MSK_RPS6KA4_ST	Q04206	RELA	O75676	RPS6KA4	S281	R274Q	274	Missense	distal	-7	no	3.852	3.571	EPSD	COSMIC	2.457	Down-regulation
AGC_RSK_MSK_RPS6KA4_ST	Q04206	RELA	O75676	RPS6KA4	S281	R278Q	278	Missense	distal	-3	no	3.852	2.349	EPSD	COSMIC	2.457	Loss
AGC_RSK_MSK_RPS6KA4_ST	Q04206	RELA	O75676	RPS6KA4	T305	R302C	302	Missense	distal	-3	no	2.640	1.234	EPSD	COSMIC	2.457	Loss
AGC_RSK_MSK_RPS6KA4_ST	Q04206	RELA	O75676	RPS6KA4	T305	E300K	300	Missense	distal	-5	no	2.640	2.694	EPSD	COSMIC	2.457	Up-regulation
AGC_RSK_MSK_RPS6KA4_ST	Q04206	RELA	O75676	RPS6KA4	T305	T305A	305	Missense	central	0	yes	2.640	0.000	EPSD	COSMIC	2.457	Loss
AGC_RSK_MSK_RPS6KA4_ST	Q04206	RELA	O75676	RPS6KA4	T308	R302C	302	Missense	distal	-6	no	2.492	2.493	EPSD	COSMIC	2.457	Up-regulation
AGC_RSK_MSK_RPS6KA4_ST	Q04206	RELA	O75676	RPS6KA4	T308	M313I	313	Missense	distal	5	no	2.492	2.581	EPSD	COSMIC	2.457	Up-regulation
AGC_RSK_MSK_RPS6KA4_ST	Q04206	RELA	O75676	RPS6KA4	T308	K314N	314	Missense	distal	6	no	2.492	2.607	EPSD	COSMIC	2.457	Up-regulation
AGC_RSK_MSK_RPS6KA4_ST	Q04206	RELA	O75676	RPS6KA4	T308	T305A	305	Missense	distal	-3	no	2.492	2.186	EPSD	COSMIC	2.457	Loss
AGC_RSK_MSK_RPS6KA4_ST	Q04206	RELA	O75676	RPS6KA4	S311	M313I	313	Missense	proximal	2	no	3.231	3.229	EPSD	COSMIC	2.457	Down-regulation
AGC_RSK_MSK_RPS6KA4_ST	Q04206	RELA	O75676	RPS6KA4	S311	K314N	314	Missense	distal	3	no	3.231	3.034	EPSD	COSMIC	2.457	Down-regulation
AGC_RSK_MSK_RPS6KA4_ST	Q04206	RELA	O75676	RPS6KA4	S311	T305A	305	Missense	distal	-6	no	3.231	3.230	EPSD	COSMIC	2.457	Down-regulation
AGC_RSK_MSK_RPS6KA4_ST	Q04206	RELA	O75676	RPS6KA4	S338	P334S	334	Missense	distal	-4	no	4.164	4.165	EPSD	COSMIC	2.457	Up-regulation
AGC_RSK_MSK_RPS6KA4_ST	Q04206	RELA	O75676	RPS6KA4	S340	P334S	334	Missense	distal	-6	no	2.941	2.942	EPSD	COSMIC	2.457	Up-regulation
AGC_RSK_MSK_RPS6KA4_ST	O75676	RPS6KA4	O75676	RPS6KA4	T84	R83L	83	Missense	proximal	-1	no	2.501	2.508	EPSD	COSMIC	2.457	Up-regulation
AGC_RSK_MSK_RPS6KA4_ST	O75676	RPS6KA4	O75676	RPS6KA4	T84	H81P	81	Missense	distal	-3	no	2.501	2.359	EPSD	COSMIC	2.457	Loss
AGC_RSK_MSK_RPS6KA4_ST	O75676	RPS6KA4	O75676	RPS6KA4	T84	R83H	83	Missense	proximal	-1	no	2.501	2.489	EPSD	COSMIC	2.457	Down-regulation
AGC_RSK_MSK_RPS6KA4_ST	O75676	RPS6KA4	O75676	RPS6KA4	T84	E80Q	80	Missense	distal	-4	no	2.501	2.497	EPSD	COSMIC	2.457	Down-regulation
AGC_RSK_MSK_RPS6KA4_ST	O75676	RPS6KA4	O75676	RPS6KA4	T178	L177I	177	Missense	proximal	-1	no	3.288	3.298	EPSD	COSMIC	2.457	Up-regulation
AGC_RSK_MSK_RPS6KA4_ST	O75676	RPS6KA4	O75676	RPS6KA4	S433	R429H	429	Missense	distal	-4	no	3.104	3.098	EPSD	COSMIC	2.457	Down-regulation
AGC_RSK_MSK_RPS6KA4_ST	O75676	RPS6KA4	O75676	RPS6KA4	S433	R431P	431	Missense	proximal	-2	no	3.104	0.726	EPSD	COSMIC	2.457	Loss
AGC_RSK_MSK_RPS6KA4_ST	O75676	RPS6KA4	O75676	RPS6KA4	S433	V439I	439	Missense	distal	6	no	3.104	3.092	EPSD	COSMIC	2.457	Down-regulation
AGC_RSK_MSK_RPS6KA4_ST	O75676	RPS6KA4	O75676	RPS6KA4	S433	A438V	438	Missense	distal	5	no	3.104	3.026	EPSD	COSMIC	2.457	Down-regulation
AGC_RSK_MSK_RPS6KA4_ST	O75676	RPS6KA4	O75676	RPS6KA4	S433	Q432H	432	Missense	proximal	-1	no	3.104	3.099	EPSD	COSMIC	2.457	Down-regulation
AGC_RSK_MSK_RPS6KA4_ST	O75676	RPS6KA4	O75676	RPS6KA4	S433	F437L	437	Missense	distal	4	no	3.104	3.091	EPSD	COSMIC	2.457	Down-regulation
AGC_RSK_MSK_RPS6KA4_ST	O75676	RPS6KA4	O75676	RPS6KA4	S502	E505V	505	Missense	distal	3	no	2.647	1.750	EPSD	COSMIC	2.457	Loss
AGC_RSK_MSK_RPS6KA4_ST	O75676	RPS6KA4	O75676	RPS6KA4	S502	R499W	499	Missense	distal	-3	no	2.647	1.325	EPSD	COSMIC;CCLE	2.457	Loss
AGC_RSK_MSK_RPS6KA4_ST	O75676	RPS6KA4	O75676	RPS6KA4	S634	E638K	638	Missense	distal	4	no	4.360	4.322	EPSD	COSMIC	2.457	Down-regulation
AGC_RSK_MSK_RPS6KA4_ST	O75676	RPS6KA4	O75676	RPS6KA4	S634	E638D	638	Missense	distal	4	no	4.360	4.367	EPSD	COSMIC	2.457	Up-regulation
AGC_RSK_MSK_RPS6KA4_ST	O75676	RPS6KA4	O75676	RPS6KA4	S634	R629H	629	Missense	distal	-5	no	4.360	4.423	EPSD	COSMIC;GDSC;CCLE	2.457	Up-regulation
AGC_RSK_MSK_RPS6KA4_ST	O75676	RPS6KA4	O75676	RPS6KA4	S634	S634F	634	Missense	central	0	yes	4.360	0.000	EPSD	COSMIC	2.457	Loss
AGC_RSK_MSK_RPS6KA4_ST	O75676	RPS6KA4	O75676	RPS6KA4	S634	E630Q	630	Missense	distal	-4	no	4.360	4.356	EPSD	COSMIC	2.457	Down-regulation
AGC_RSK_MSK_RPS6KA4_ST	O75676	RPS6KA4	O75676	RPS6KA4	S634	L635F	635	Missense	proximal	1	no	4.360	4.410	EPSD	COSMIC	2.457	Up-regulation
AGC_RSK_MSK_RPS6KA4_ST	O75676	RPS6KA4	O75676	RPS6KA4	S634	K627R	627	Missense	distal	-7	no	4.360	4.477	EPSD	COSMIC	2.457	Up-regulation
AGC_RSK_MSK_RPS6KA4_ST	O75676	RPS6KA4	O75676	RPS6KA4	S634	G637V	637	Missense	distal	3	no	4.360	3.520	EPSD	COSMIC	2.457	Down-regulation
AGC_RSK_MSK_RPS6KA4_ST	O75676	RPS6KA4	O75676	RPS6KA4	S671	R669Q	669	Missense	proximal	-2	no	3.640	1.140	EPSD	COSMIC	2.457	Loss
AGC_RSK_MSK_RPS6KA4_ST	O75676	RPS6KA4	O75676	RPS6KA4	S671	S672L	672	Missense	proximal	1	no	3.640	3.656	EPSD	COSMIC	2.457	Up-regulation
AGC_RSK_MSK_RPS6KA4_ST	O75676	RPS6KA4	O75676	RPS6KA4	S682	R686W	686	Missense	distal	4	no	3.084	3.112	EPSD	COSMIC	2.457	Up-regulation
AGC_RSK_MSK_RPS6KA4_ST	O75676	RPS6KA4	O75676	RPS6KA4	S682	R680C	680	Missense	proximal	-2	no	3.084	0.947	EPSD	COSMIC	2.457	Loss
AGC_RSK_MSK_RPS6KA4_ST	O75676	RPS6KA4	O75676	RPS6KA4	S682	R680L	680	Missense	proximal	-2	no	3.084	0.718	EPSD	COSMIC	2.457	Loss
AGC_RSK_MSK_RPS6KA4_ST	O75676	RPS6KA4	O75676	RPS6KA4	S682	A679P	679	Missense	distal	-3	no	3.084	2.472	EPSD	COSMIC	2.457	Down-regulation
AGC_RSK_MSK_RPS6KA4_ST	O75676	RPS6KA4	O75676	RPS6KA4	S682	P683S	683	Missense	proximal	1	no	3.084	3.067	EPSD	COSMIC;CCLE	2.457	Down-regulation
AGC_RSK_MSK_RPS6KA4_ST	O75676	RPS6KA4	O75676	RPS6KA4	S682	S682L	682	Missense	central	0	yes	3.084	0.000	EPSD	COSMIC	2.457	Loss
AGC_RSK_MSK_RPS6KA4_ST	O75676	RPS6KA4	O75676	RPS6KA4	S682	P684L	684	Missense	proximal	2	no	3.084	3.080	EPSD	COSMIC	2.457	Down-regulation
AGC_RSK_MSK_RPS6KA4_ST	O75676	RPS6KA4	O75676	RPS6KA4	S693	A697T	697	Missense	distal	4	no	2.790	2.755	EPSD	COSMIC	2.457	Down-regulation
AGC_RSK_MSK_RPS6KA4_ST	O75676	RPS6KA4	O75676	RPS6KA4	S693	R699C	699	Missense	distal	6	no	2.790	2.903	EPSD	COSMIC	2.457	Up-regulation
AGC_RSK_MSK_RPS6KA4_ST	O75676	RPS6KA4	O75676	RPS6KA4	S693	R686W	686	Missense	distal	-7	no	2.790	2.543	EPSD	COSMIC	2.457	Down-regulation
AGC_RSK_MSK_RPS6KA4_ST	O75676	RPS6KA4	O75676	RPS6KA4	S693	V698M	698	Missense	distal	5	no	2.790	2.785	EPSD	COSMIC	2.457	Down-regulation
AGC_RSK_MSK_RPS6KA4_ST	O75676	RPS6KA4	O75676	RPS6KA4	S693	S694C	694	Missense	proximal	1	no	2.790	2.837	EPSD	COSMIC	2.457	Up-regulation
AGC_RSK_MSK_RPS6KA4_ST	O75676	RPS6KA4	O75676	RPS6KA4	S693	S694F	694	Missense	proximal	1	no	2.790	2.856	EPSD	COSMIC	2.457	Up-regulation
AGC_RSK_MSK_RPS6KA4_ST	O75676	RPS6KA4	O75676	RPS6KA4	S693	V690M	690	Missense	distal	-3	no	2.790	2.514	EPSD	COSMIC	2.457	Down-regulation
AGC_RSK_MSK_RPS6KA4_ST	O75676	RPS6KA4	O75676	RPS6KA4	S745	A749T	749	Missense	distal	4	no	3.872	3.837	EPSD	COSMIC	2.457	Down-regulation
AGC_RSK_MSK_RPS6KA4_ST	O75676	RPS6KA4	O75676	RPS6KA4	S745	P746T	746	Missense	proximal	1	no	3.872	3.924	EPSD	COSMIC	2.457	Up-regulation
AGC_RSK_MSK_RPS6KA4_ST	O75676	RPS6KA4	O75676	RPS6KA4	S745	R742H	742	Missense	distal	-3	no	3.872	2.431	EPSD	COSMIC	2.457	Loss
AGC_RSK_MSK_RPS6KA4_ST	O75676	RPS6KA4	O75676	RPS6KA4	S745	P751L	751	Missense	distal	6	no	3.872	3.687	EPSD	COSMIC	2.457	Down-regulation
TKL_MLK_ILK_ILK_ST	O14950	MYL12B	Q13418	ILK	T11	K12N	12	Missense	proximal	1	no	13.645	15.349	EPSD	COSMIC	15.108	Gain
TKL_MLK_ILK_ILK_ST	O14950	MYL12B	Q13418	ILK	T19	M25L	25	Missense	distal	6	no	21.935	19.749	EPSD;PhosphoSitePlus	COSMIC	15.108	Down-regulation
TKL_MLK_ILK_ILK_ST	O14950	MYL12B	Q13418	ILK	T19	K12N	12	Missense	distal	-7	no	21.935	21.933	EPSD;PhosphoSitePlus	COSMIC	15.108	Down-regulation
TKL_MLK_ILK_ILK_ST	O14950	MYL12B	Q13418	ILK	S20	M25L	25	Missense	distal	5	no	20.941	20.531	PhosphoSitePlus;EPSD	COSMIC	15.108	Down-regulation
TKL_MLK_ILK_ILK_ST	P31749	AKT1	Q13418	ILK	T34	G37D	37	Missense	distal	3	no	18.369	18.379	EPSD	COSMIC	15.108	Up-regulation
TKL_MLK_ILK_ILK_ST	P31749	AKT1	Q13418	ILK	T34	D32N	32	Missense	proximal	-2	no	18.369	19.302	EPSD	COSMIC	15.108	Up-regulation
TKL_MLK_ILK_ILK_ST	P31749	AKT1	Q13418	ILK	T34	F35L	35	Missense	proximal	1	no	18.369	17.496	EPSD	COSMIC	15.108	Down-regulation
TKL_MLK_ILK_ILK_ST	P31749	AKT1	Q13418	ILK	T34	L28V	28	Missense	distal	-6	no	18.369	18.107	EPSD	COSMIC	15.108	Down-regulation
TKL_MLK_ILK_ILK_ST	P31749	AKT1	Q13418	ILK	T34	F35I	35	Missense	proximal	1	no	18.369	18.725	EPSD	COSMIC	15.108	Up-regulation
TKL_MLK_ILK_ILK_ST	P31749	AKT1	Q13418	ILK	T34	K39N	39	Missense	distal	5	no	18.369	18.292	EPSD	COSMIC	15.108	Down-regulation
TKL_MLK_ILK_ILK_ST	P31749	AKT1	Q13418	ILK	T34	D32Y	32	Missense	proximal	-2	no	18.369	21.773	EPSD	COSMIC	15.108	Up-regulation
TKL_MLK_ILK_ILK_ST	P31749	AKT1	Q13418	ILK	T65	R67Q	67	Missense	proximal	2	no	15.698	16.304	EPSD	COSMIC	15.108	Up-regulation
TKL_MLK_ILK_ILK_ST	P31749	AKT1	Q13418	ILK	T65	L62R	62	Missense	distal	-3	no	15.698	16.528	EPSD	COSMIC	15.108	Up-regulation
TKL_MLK_ILK_ILK_ST	P31749	AKT1	Q13418	ILK	T65	R69L	69	Missense	distal	4	no	15.698	15.704	EPSD	COSMIC	15.108	Up-regulation
TKL_MLK_ILK_ILK_ST	P31749	AKT1	Q13418	ILK	T65	M63I	63	Missense	proximal	-2	no	15.698	6.100	EPSD	COSMIC	15.108	Loss
TKL_MLK_ILK_ILK_ST	P31749	AKT1	Q13418	ILK	T65	P70L	70	Missense	distal	5	no	15.698	16.702	EPSD	COSMIC	15.108	Up-regulation
TKL_MLK_ILK_ILK_ST	P31749	AKT1	Q13418	ILK	T430	T435I	435	Missense	distal	5	no	23.358	22.953	EPSD	COSMIC	15.108	Down-regulation
TKL_MLK_ILK_ILK_ST	P31749	AKT1	Q13418	ILK	T430	T430M	430	Missense	central	0	yes	23.358	0.000	EPSD	COSMIC	15.108	Loss
TKL_MLK_ILK_ILK_ST	Q96A00	PPP1R14A	Q13418	ILK	T38	V39I	39	Missense	proximal	1	no	44.965	45.318	PhosphoSitePlus	COSMIC;CCLE	15.108	Up-regulation
TKL_MLK_ILK_ILK_ST	Q96A00	PPP1R14A	Q13418	ILK	T38	D42N	42	Missense	distal	4	no	44.965	44.979	PhosphoSitePlus	COSMIC	15.108	Up-regulation
TKL_MLK_ILK_ILK_ST	Q8TAE6	PPP1R14C	Q13418	ILK	T73	R78H	78	Missense	distal	5	no	43.142	42.754	PhosphoSitePlus	COSMIC	15.108	Down-regulation
TKL_MLK_ILK_ILK_ST	Q8TAE6	PPP1R14C	Q13418	ILK	T73	H67Y	67	Missense	distal	-6	no	43.142	43.125	PhosphoSitePlus	COSMIC	15.108	Down-regulation
TKL_MLK_ILK_ILK_ST	Q8TAE6	PPP1R14C	Q13418	ILK	T73	Q69R	69	Missense	distal	-4	no	43.142	40.511	PhosphoSitePlus	COSMIC;GDSC;CCLE	15.108	Down-regulation
TKL_MLK_ILK_ILK_ST	E9PAV3	NACA	Q13418	ILK	S868	T871P	871	Missense	distal	3	no	15.982	14.548	EPSD	COSMIC	15.108	Loss
TKL_MLK_ILK_ILK_ST	E9PAV3	NACA	Q13418	ILK	T1015	S1022G	1022	Missense	distal	7	no	18.747	18.056	EPSD	COSMIC	15.108	Down-regulation
TKL_MLK_ILK_ILK_ST	E9PAV3	NACA	Q13418	ILK	T1015	V1014A	1014	Missense	proximal	-1	no	18.747	19.071	EPSD	COSMIC	15.108	Up-regulation
TKL_MLK_ILK_ILK_ST	E9PAV3	NACA	Q13418	ILK	T1015	T1010P	1010	Missense	distal	-5	no	18.747	18.582	EPSD	COSMIC	15.108	Down-regulation
TKL_MLK_ILK_ILK_ST	E9PAV3	NACA	Q13418	ILK	T1015	A1008V	1008	Missense	distal	-7	no	18.747	18.744	EPSD	COSMIC	15.108	Down-regulation
TKL_MLK_ILK_ILK_ST	E9PAV3	NACA	Q13418	ILK	T1015	P1012L	1012	Missense	distal	-3	no	18.747	18.015	EPSD	COSMIC	15.108	Down-regulation
TKL_MLK_ILK_ILK_ST	E9PAV3	NACA	Q13418	ILK	T1015	A1008D	1008	Missense	distal	-7	no	18.747	18.745	EPSD	COSMIC;CCLE	15.108	Down-regulation
TKL_MLK_ILK_ILK_ST	E9PAV3	NACA	Q13418	ILK	T1339	G1345E	1345	Missense	distal	6	no	16.295	16.267	EPSD	COSMIC	15.108	Down-regulation
TKL_MLK_ILK_ILK_ST	E9PAV3	NACA	Q13418	ILK	S1581	S1576Y	1576	Missense	distal	-5	no	16.375	16.658	EPSD	COSMIC	15.108	Up-regulation
TKL_MLK_ILK_ILK_ST	E9PAV3	NACA	Q13418	ILK	T1586	S1581T	1581	Missense	distal	-5	no	15.253	15.398	EPSD	COSMIC	15.108	Up-regulation
TKL_MLK_ILK_ILK_ST	E9PAV3	NACA	Q13418	ILK	S1906	E1902K	1902	Missense	distal	-4	no	48.271	46.972	PhosphoSitePlus	COSMIC	15.108	Down-regulation
TKL_MLK_ILK_ILK_ST	E9PAV3	NACA	Q13418	ILK	S1906	L1901P	1901	Missense	distal	-5	no	48.271	48.136	PhosphoSitePlus	COSMIC	15.108	Down-regulation
TKL_MLK_ILK_ILK_ST	E9PAV3	NACA	Q13418	ILK	T1958	I1959L	1959	Missense	proximal	1	no	20.820	19.591	EPSD	COSMIC	15.108	Down-regulation
TKL_MLK_ILK_ILK_ST	E9PAV3	NACA	Q13418	ILK	T1958	I1959V	1959	Missense	proximal	1	no	20.820	20.467	EPSD	COSMIC	15.108	Down-regulation
TKL_MLK_ILK_ILK_ST	E9PAV3	NACA	Q13418	ILK	T1958	R1960Q	1960	Missense	proximal	2	no	20.820	21.426	EPSD	COSMIC	15.108	Up-regulation
TKL_MLK_ILK_ILK_ST	E9PAV3	NACA	Q13418	ILK	S1962	L1966I	1966	Missense	distal	4	no	19.333	19.374	EPSD	COSMIC	15.108	Up-regulation
TKL_MLK_ILK_ILK_ST	E9PAV3	NACA	Q13418	ILK	S1962	I1959L	1959	Missense	distal	-3	no	19.333	19.707	EPSD	COSMIC	15.108	Up-regulation
TKL_MLK_ILK_ILK_ST	E9PAV3	NACA	Q13418	ILK	S1962	I1959V	1959	Missense	distal	-3	no	19.333	20.877	EPSD	COSMIC	15.108	Up-regulation
TKL_MLK_ILK_ILK_ST	E9PAV3	NACA	Q13418	ILK	S1962	R1960Q	1960	Missense	proximal	-2	no	19.333	23.306	EPSD	COSMIC	15.108	Up-regulation
TKL_MLK_ILK_ILK_ST	E9PAV3	NACA	Q13418	ILK	S1977	Y1975C	1975	Missense	proximal	-2	no	23.596	22.832	EPSD	COSMIC	15.108	Down-regulation
CK1_VRK_VRK1_ST	P38432	COIL	Q99986	VRK1	S129	K130N	130	Missense	proximal	1	no	0.325	0.316	EPSD	COSMIC	0.296	Down-regulation
CK1_VRK_VRK1_ST	P38432	COIL	Q99986	VRK1	S129	D125V	125	Missense	distal	-4	no	0.325	0.297	EPSD	COSMIC	0.296	Down-regulation
CK1_VRK_VRK1_ST	P38432	COIL	Q99986	VRK1	S184	A180V	180	Missense	distal	-4	no	0.498	0.451	PhosphoSitePlus	COSMIC;GDSC	0.296	Down-regulation
CK1_VRK_VRK1_ST	P38432	COIL	Q99986	VRK1	S184	A180S	180	Missense	distal	-4	no	0.498	0.452	PhosphoSitePlus	COSMIC	0.296	Down-regulation
CK1_VRK_VRK1_ST	P38432	COIL	Q99986	VRK1	S305	L298V	298	Missense	distal	-7	no	0.281	0.334	EPSD	COSMIC	0.296	Gain
CK1_VRK_VRK1_ST	P38432	COIL	Q99986	VRK1	S316	S314F	314	Missense	proximal	-2	no	0.297	0.304	EPSD	COSMIC	0.296	Up-regulation
CK1_VRK_VRK1_ST	P38432	COIL	Q99986	VRK1	S486	S493C	493	Missense	distal	7	no	0.327	0.331	EPSD	COSMIC	0.296	Up-regulation
CK1_VRK_VRK1_ST	P38432	COIL	Q99986	VRK1	S486	S486C	486	Missense	central	0	yes	0.327	0.000	EPSD	COSMIC	0.296	Loss
CK1_VRK_VRK1_ST	P38432	COIL	Q99986	VRK1	S487	S493C	493	Missense	distal	6	no	0.339	0.334	EPSD	COSMIC	0.296	Down-regulation
CK1_VRK_VRK1_ST	P05412	JUN	Q99986	VRK1	S58	L53F	53	Missense	distal	-5	no	0.311	0.312	EPSD	COSMIC	0.296	Up-regulation
CK1_VRK_VRK1_ST	P05412	JUN	Q99986	VRK1	S58	K56N	56	Missense	proximal	-2	no	0.311	0.312	EPSD	COSMIC	0.296	Up-regulation
CK1_VRK_VRK1_ST	P05412	JUN	Q99986	VRK1	S58	P51T	51	Missense	distal	-7	no	0.311	0.279	EPSD	COSMIC;CCLE	0.296	Loss
CK1_VRK_VRK1_ST	P05412	JUN	Q99986	VRK1	S58	L61F	61	Missense	distal	3	no	0.311	0.294	EPSD	COSMIC	0.296	Loss
CK1_VRK_VRK1_ST	P05412	JUN	Q99986	VRK1	S63	K56N	56	Missense	distal	-7	no	0.433	0.429	EPSD;PhosphoSitePlus	COSMIC	0.296	Down-regulation
CK1_VRK_VRK1_ST	P05412	JUN	Q99986	VRK1	S63	L61F	61	Missense	proximal	-2	no	0.433	0.421	EPSD;PhosphoSitePlus	COSMIC	0.296	Down-regulation
CK1_VRK_VRK1_ST	P05412	JUN	Q99986	VRK1	S73	R78H	78	Missense	distal	5	no	0.503	0.501	PhosphoSitePlus;EPSD	COSMIC	0.296	Down-regulation
CK1_VRK_VRK1_ST	P15336	ATF2	Q99986	VRK1	S62	I64V	64	Missense	proximal	2	no	0.560	0.562	PhosphoSitePlus;EPSD	COSMIC	0.296	Up-regulation
CK1_VRK_VRK1_ST	P15336	ATF2	Q99986	VRK1	S62	D67E	67	Missense	distal	5	no	0.560	0.549	PhosphoSitePlus;EPSD	COSMIC	0.296	Down-regulation
CK1_VRK_VRK1_ST	P15336	ATF2	Q99986	VRK1	S62	G56V	56	Missense	distal	-6	no	0.560	0.517	PhosphoSitePlus;EPSD	COSMIC	0.296	Down-regulation
CK1_VRK_VRK1_ST	P15336	ATF2	Q99986	VRK1	T73	T73A	73	Missense	central	0	yes	0.514	0.000	EPSD;PhosphoSitePlus	COSMIC	0.296	Loss
CK1_VRK_VRK1_ST	P15336	ATF2	Q99986	VRK1	T73	F75L	75	Missense	proximal	2	no	0.514	0.480	EPSD;PhosphoSitePlus	COSMIC	0.296	Down-regulation
CK1_VRK_VRK1_ST	P15336	ATF2	Q99986	VRK1	T73	R74T	74	Missense	proximal	1	no	0.514	0.510	EPSD;PhosphoSitePlus	COSMIC	0.296	Down-regulation
CK1_VRK_VRK1_ST	P15336	ATF2	Q99986	VRK1	T73	D67E	67	Missense	distal	-6	no	0.514	0.496	EPSD;PhosphoSitePlus	COSMIC	0.296	Down-regulation
CK1_VRK_VRK1_ST	P15336	ATF2	Q99986	VRK1	S100	M107I	107	Missense	distal	7	no	0.327	0.332	EPSD	COSMIC;GDSC;CCLE	0.296	Up-regulation
CK1_VRK_VRK1_ST	P15336	ATF2	Q99986	VRK1	S100	K105T	105	Missense	distal	5	no	0.327	0.326	EPSD	COSMIC;GDSC;CCLE	0.296	Down-regulation
CK1_VRK_VRK1_ST	P15336	ATF2	Q99986	VRK1	S100	K106R	106	Missense	distal	6	no	0.327	0.316	EPSD	COSMIC	0.296	Down-regulation
CK1_VRK_VRK1_ST	P15336	ATF2	Q99986	VRK1	T116	D110E	110	Missense	distal	-6	no	0.320	0.303	EPSD	COSMIC	0.296	Down-regulation
CK1_VRK_VRK1_ST	P15336	ATF2	Q99986	VRK1	S136	P141T	141	Missense	distal	5	no	0.374	0.371	EPSD	COSMIC	0.296	Down-regulation
CK1_VRK_VRK1_ST	P15336	ATF2	Q99986	VRK1	S136	P141L	141	Missense	distal	5	no	0.374	0.373	EPSD	COSMIC	0.296	Down-regulation
CK1_VRK_VRK1_ST	P15336	ATF2	Q99986	VRK1	S136	P137S	137	Missense	proximal	1	no	0.374	0.366	EPSD	COSMIC	0.296	Down-regulation
CK1_VRK_VRK1_ST	P15336	ATF2	Q99986	VRK1	T305	T305I	305	Missense	central	0	yes	0.369	0.000	EPSD	COSMIC	0.296	Loss
CK1_VRK_VRK1_ST	P15336	ATF2	Q99986	VRK1	T305	R311Q	311	Missense	distal	6	no	0.369	0.370	EPSD	COSMIC;GDSC;CCLE	0.296	Up-regulation
CK1_VRK_VRK1_ST	P15336	ATF2	Q99986	VRK1	T305	G299D	299	Missense	distal	-6	no	0.369	0.328	EPSD	COSMIC	0.296	Down-regulation
CK1_VRK_VRK1_ST	P15336	ATF2	Q99986	VRK1	S310	T305I	305	Missense	distal	-5	no	0.396	0.359	EPSD	COSMIC	0.296	Down-regulation
CK1_VRK_VRK1_ST	P15336	ATF2	Q99986	VRK1	S310	R311Q	311	Missense	proximal	1	no	0.396	0.401	EPSD	COSMIC;GDSC;CCLE	0.296	Up-regulation
CK1_VRK_VRK1_ST	P15336	ATF2	Q99986	VRK1	S310	Q316K	316	Missense	distal	6	no	0.396	0.406	EPSD	COSMIC	0.296	Up-regulation
CK1_VRK_VRK1_ST	P15336	ATF2	Q99986	VRK1	S310	Q317H	317	Missense	distal	7	no	0.396	0.393	EPSD	COSMIC	0.296	Down-regulation
CK1_VRK_VRK1_ST	P04637	TP53	Q99986	VRK1	T18	E11Q	11	Missense	distal	-7	no	0.435	0.390	PhosphoSitePlus	COSMIC;GDSC;CCLE	0.296	Down-regulation
CK1_VRK_VRK1_ST	P04637	TP53	Q99986	VRK1	T18	S20L	20	Missense	proximal	2	no	0.435	0.388	PhosphoSitePlus	COSMIC	0.296	Down-regulation
CK1_VRK_VRK1_ST	P04637	TP53	Q99986	VRK1	T18	Q16L	16	Missense	proximal	-2	no	0.435	0.445	PhosphoSitePlus	COSMIC;GDSC;CCLE	0.296	Up-regulation
CK1_VRK_VRK1_ST	P04637	TP53	Q99986	VRK1	T18	P13S	13	Missense	distal	-5	no	0.435	0.399	PhosphoSitePlus	COSMIC	0.296	Down-regulation
CK1_VRK_VRK1_ST	P04637	TP53	Q99986	VRK1	T18	E17K	17	Missense	proximal	-1	no	0.435	0.432	PhosphoSitePlus	COSMIC	0.296	Down-regulation
CK1_VRK_VRK1_ST	P04637	TP53	Q99986	VRK1	T18	P13L	13	Missense	distal	-5	no	0.435	0.407	PhosphoSitePlus	COSMIC	0.296	Down-regulation
CK1_VRK_VRK1_ST	P04637	TP53	Q99986	VRK1	T18	T18A	18	Missense	central	0	yes	0.435	0.000	PhosphoSitePlus	COSMIC	0.296	Loss
CK1_VRK_VRK1_ST	P04637	TP53	Q99986	VRK1	T18	F19S	19	Missense	proximal	1	no	0.435	0.438	PhosphoSitePlus	COSMIC	0.296	Up-regulation
CK1_VRK_VRK1_ST	P04637	TP53	Q99986	VRK1	T18	E17V	17	Missense	proximal	-1	no	0.435	0.441	PhosphoSitePlus	COSMIC	0.296	Up-regulation
CK1_VRK_VRK1_ST	P04637	TP53	Q99986	VRK1	T18	T18I	18	Missense	central	0	yes	0.435	0.000	PhosphoSitePlus	COSMIC	0.296	Loss
CK1_VRK_VRK1_ST	P04637	TP53	Q99986	VRK1	T18	T18K	18	Missense	central	0	yes	0.435	0.000	PhosphoSitePlus	COSMIC	0.296	Loss
CK1_VRK_VRK1_ST	P04637	TP53	Q99986	VRK1	T18	T18R	18	Missense	central	0	yes	0.435	0.000	PhosphoSitePlus	COSMIC	0.296	Loss
CK1_VRK_VRK1_ST	P04637	TP53	Q99986	VRK1	S20	Q16L	16	Missense	distal	-4	no	0.267	0.307	EPSD	COSMIC;GDSC;CCLE	0.296	Gain
CK1_VRK_VRK1_ST	P04637	TP53	Q99986	VRK1	S46	M40I	40	Missense	distal	-6	no	0.281	0.304	EPSD	COSMIC	0.296	Gain
CK1_VRK_VRK1_ST	P04637	TP53	Q99986	VRK1	S46	A39V	39	Missense	distal	-7	no	0.281	0.313	EPSD	COSMIC	0.296	Gain
CK1_VRK_VRK1_ST	P04637	TP53	Q99986	VRK1	S46	D41H	41	Missense	distal	-5	no	0.281	0.302	EPSD	COSMIC	0.296	Gain
CK1_VRK_VRK1_ST	P04637	TP53	Q99986	VRK1	S46	D41E	41	Missense	distal	-5	no	0.281	0.298	EPSD	COSMIC	0.296	Gain
CK1_VRK_VRK1_ST	P04637	TP53	Q99986	VRK1	S149	P142T	142	Missense	distal	-7	no	0.377	0.344	EPSD	COSMIC	0.296	Down-regulation
CK1_VRK_VRK1_ST	P04637	TP53	Q99986	VRK1	S149	P142S	142	Missense	distal	-7	no	0.377	0.365	EPSD	COSMIC	0.296	Down-regulation
CK1_VRK_VRK1_ST	P04637	TP53	Q99986	VRK1	S149	P151N	151	Missense	proximal	2	no	0.377	0.364	EPSD	COSMIC	0.296	Down-regulation
CK1_VRK_VRK1_ST	P04637	TP53	Q99986	VRK1	S149	P152A	152	Missense	distal	3	no	0.377	0.368	EPSD	COSMIC	0.296	Down-regulation
CK1_VRK_VRK1_ST	P04637	TP53	Q99986	VRK1	S149	P152T	152	Missense	distal	3	no	0.377	0.379	EPSD	COSMIC	0.296	Up-regulation
CK1_VRK_VRK1_ST	P04637	TP53	Q99986	VRK1	S149	P152H	152	Missense	distal	3	no	0.377	0.395	EPSD	COSMIC	0.296	Up-regulation
CK1_VRK_VRK1_ST	P04637	TP53	Q99986	VRK1	S149	P142A	142	Missense	distal	-7	no	0.377	0.370	EPSD	COSMIC	0.296	Down-regulation
CK1_VRK_VRK1_ST	P04637	TP53	Q99986	VRK1	S149	P142F	142	Missense	distal	-7	no	0.377	0.396	EPSD	COSMIC	0.296	Up-regulation
CK1_VRK_VRK1_ST	P04637	TP53	Q99986	VRK1	S149	P153T	153	Missense	distal	4	no	0.377	0.362	EPSD	COSMIC	0.296	Down-regulation
CK1_VRK_VRK1_ST	P04637	TP53	Q99986	VRK1	S149	V147I	147	Missense	proximal	-2	no	0.377	0.387	EPSD	COSMIC	0.296	Up-regulation
CK1_VRK_VRK1_ST	P04637	TP53	Q99986	VRK1	S149	P153L	153	Missense	distal	4	no	0.377	0.373	EPSD	COSMIC	0.296	Down-regulation
CK1_VRK_VRK1_ST	P04637	TP53	Q99986	VRK1	S149	V147D	147	Missense	proximal	-2	no	0.377	0.384	EPSD	COSMIC;GDSC;CCLE	0.296	Up-regulation
CK1_VRK_VRK1_ST	P04637	TP53	Q99986	VRK1	S149	S149P	149	Missense	central	0	yes	0.377	0.000	EPSD	COSMIC	0.296	Loss
CK1_VRK_VRK1_ST	P04637	TP53	Q99986	VRK1	S149	P152K	152	Missense	distal	3	no	0.377	0.387	EPSD	COSMIC	0.296	Up-regulation
CK1_VRK_VRK1_ST	P04637	TP53	Q99986	VRK1	S149	P153S	153	Missense	distal	4	no	0.377	0.373	EPSD	COSMIC	0.296	Down-regulation
CK1_VRK_VRK1_ST	P04637	TP53	Q99986	VRK1	S149	G154C	154	Missense	distal	5	no	0.377	0.375	EPSD	COSMIC	0.296	Down-regulation
CK1_VRK_VRK1_ST	P04637	TP53	Q99986	VRK1	S149	S149F	149	Missense	central	0	yes	0.377	0.000	EPSD	COSMIC	0.296	Loss
CK1_VRK_VRK1_ST	P04637	TP53	Q99986	VRK1	S149	G154D	154	Missense	distal	5	no	0.377	0.381	EPSD	COSMIC	0.296	Up-regulation
CK1_VRK_VRK1_ST	P04637	TP53	Q99986	VRK1	S149	Q144R	144	Missense	distal	-5	no	0.377	0.366	EPSD	COSMIC	0.296	Down-regulation
CK1_VRK_VRK1_ST	P04637	TP53	Q99986	VRK1	S149	D148V	148	Missense	proximal	-1	no	0.377	0.381	EPSD	COSMIC	0.296	Up-regulation
CK1_VRK_VRK1_ST	P04637	TP53	Q99986	VRK1	S149	S149Y	149	Missense	central	0	yes	0.377	0.000	EPSD	COSMIC	0.296	Loss
CK1_VRK_VRK1_ST	P04637	TP53	Q99986	VRK1	S149	T150I	150	Missense	proximal	1	no	0.377	0.374	EPSD	COSMIC	0.296	Down-regulation
CK1_VRK_VRK1_ST	P04637	TP53	Q99986	VRK1	S149	L145M	145	Missense	distal	-4	no	0.377	0.355	EPSD	COSMIC	0.296	Down-regulation
CK1_VRK_VRK1_ST	P04637	TP53	Q99986	VRK1	S149	V143L	143	Missense	distal	-6	no	0.377	0.352	EPSD	COSMIC	0.296	Down-regulation
CK1_VRK_VRK1_ST	P04637	TP53	Q99986	VRK1	S149	R156S	156	Missense	distal	7	no	0.377	0.374	EPSD	COSMIC	0.296	Down-regulation
CK1_VRK_VRK1_ST	P04637	TP53	Q99986	VRK1	S149	D148E	148	Missense	proximal	-1	no	0.377	0.376	EPSD	COSMIC	0.296	Down-regulation
CK1_VRK_VRK1_ST	P04637	TP53	Q99986	VRK1	S149	V147F	147	Missense	proximal	-2	no	0.377	0.382	EPSD	COSMIC	0.296	Up-regulation
CK1_VRK_VRK1_ST	P04637	TP53	Q99986	VRK1	S149	T155A	155	Missense	distal	6	no	0.377	0.381	EPSD	COSMIC	0.296	Up-regulation
CK1_VRK_VRK1_ST	P04637	TP53	Q99986	VRK1	S149	V147E	147	Missense	proximal	-2	no	0.377	0.382	EPSD	COSMIC	0.296	Up-regulation
CK1_VRK_VRK1_ST	P04637	TP53	Q99986	VRK1	S149	G154I	154	Missense	distal	5	no	0.377	0.376	EPSD	COSMIC	0.296	Down-regulation
CK1_VRK_VRK1_ST	P04637	TP53	Q99986	VRK1	S149	D148G	148	Missense	proximal	-1	no	0.377	0.382	EPSD	COSMIC	0.296	Up-regulation
CK1_VRK_VRK1_ST	P04637	TP53	Q99986	VRK1	S149	Q144K	144	Missense	distal	-5	no	0.377	0.359	EPSD	COSMIC	0.296	Down-regulation
CK1_VRK_VRK1_ST	P04637	TP53	Q99986	VRK1	S149	V147A	147	Missense	proximal	-2	no	0.377	0.389	EPSD	COSMIC	0.296	Up-regulation
CK1_VRK_VRK1_ST	P04637	TP53	Q99986	VRK1	S149	L145V	145	Missense	distal	-4	no	0.377	0.321	EPSD	COSMIC	0.296	Down-regulation
CK1_VRK_VRK1_ST	P04637	TP53	Q99986	VRK1	S149	T150K	150	Missense	proximal	1	no	0.377	0.386	EPSD	COSMIC	0.296	Up-regulation
CK1_VRK_VRK1_ST	P04637	TP53	Q99986	VRK1	S149	P153H	153	Missense	distal	4	no	0.377	0.371	EPSD	COSMIC	0.296	Down-regulation
CK1_VRK_VRK1_ST	P04637	TP53	Q99986	VRK1	S149	P142Q	142	Missense	distal	-7	no	0.377	0.361	EPSD	COSMIC	0.296	Down-regulation
CK1_VRK_VRK1_ST	P04637	TP53	Q99986	VRK1	S149	T155S	155	Missense	distal	6	no	0.377	0.384	EPSD	COSMIC;CCLE	0.296	Up-regulation
CK1_VRK_VRK1_ST	P04637	TP53	Q99986	VRK1	S149	D148H	148	Missense	proximal	-1	no	0.377	0.376	EPSD	COSMIC	0.296	Down-regulation
CK1_VRK_VRK1_ST	P04637	TP53	Q99986	VRK1	S149	T150R	150	Missense	proximal	1	no	0.377	0.381	EPSD	COSMIC	0.296	Up-regulation
CK1_VRK_VRK1_ST	P04637	TP53	Q99986	VRK1	S149	T155L	155	Missense	distal	6	no	0.377	0.379	EPSD	COSMIC	0.296	Up-regulation
CK1_VRK_VRK1_ST	P04637	TP53	Q99986	VRK1	S149	G154A	154	Missense	distal	5	no	0.377	0.373	EPSD	COSMIC	0.296	Down-regulation
CK1_VRK_VRK1_ST	P04637	TP53	Q99986	VRK1	S149	T150A	150	Missense	proximal	1	no	0.377	0.376	EPSD	COSMIC	0.296	Down-regulation
CK1_VRK_VRK1_ST	P04637	TP53	Q99986	VRK1	S149	P153F	153	Missense	distal	4	no	0.377	0.358	EPSD	COSMIC	0.296	Down-regulation
CK1_VRK_VRK1_ST	P04637	TP53	Q99986	VRK1	S149	G154R	154	Missense	distal	5	no	0.377	0.381	EPSD	COSMIC	0.296	Up-regulation
CK1_VRK_VRK1_ST	P04637	TP53	Q99986	VRK1	S215	R209G	209	Missense	distal	-6	no	0.198	0.329	EPSD	COSMIC	0.296	Gain
CK1_VRK_VRK1_ST	O75469	NR1I2	Q99986	VRK1	S350	A345D	345	Missense	distal	-5	no	0.491	0.450	PhosphoSitePlus	COSMIC	0.296	Down-regulation
CK1_VRK_VRK1_ST	O75469	NR1I2	Q99986	VRK1	S350	L348I	348	Missense	proximal	-2	no	0.491	0.484	PhosphoSitePlus	COSMIC	0.296	Down-regulation
CK1_VRK_VRK1_ST	O75469	NR1I2	Q99986	VRK1	S350	R353H	353	Missense	distal	3	no	0.491	0.501	PhosphoSitePlus	COSMIC	0.296	Up-regulation
CK1_VRK_VRK1_ST	O75469	NR1I2	Q99986	VRK1	S350	L357F	357	Missense	distal	7	no	0.491	0.488	PhosphoSitePlus	COSMIC	0.296	Down-regulation
CK1_VRK_VRK1_ST	Q99986	VRK1	Q99986	VRK1	T355	K359E	359	Missense	distal	4	no	0.477	0.473	PhosphoSitePlus	COSMIC	0.296	Down-regulation
AGC_PKC_PKCi_PRKCI_ST	Q7KZI7	MARK2	P41743	PRKCI	T6	E13K	13	Missense	distal	7	no	8.886	8.862	EPSD	COSMIC	6.376	Down-regulation
AGC_PKC_PKCi_PRKCI_ST	Q7KZI7	MARK2	P41743	PRKCI	T6	S2C	2	Missense	distal	-4	no	8.886	8.376	EPSD	COSMIC	6.376	Down-regulation
AGC_PKC_PKCi_PRKCI_ST	Q7KZI7	MARK2	P41743	PRKCI	T20	L24V	24	Missense	distal	4	no	6.235	6.426	EPSD	COSMIC	6.376	Gain
AGC_PKC_PKCi_PRKCI_ST	Q7KZI7	MARK2	P41743	PRKCI	S30	L24V	24	Missense	distal	-6	no	8.250	8.078	EPSD	COSMIC	6.376	Down-regulation
AGC_PKC_PKCi_PRKCI_ST	Q7KZI7	MARK2	P41743	PRKCI	S424	N430D	430	Missense	distal	6	no	10.983	10.892	EPSD	COSMIC	6.376	Down-regulation
AGC_PKC_PKCi_PRKCI_ST	Q7KZI7	MARK2	P41743	PRKCI	S424	N431D	431	Missense	distal	7	no	10.983	10.916	EPSD	COSMIC	6.376	Down-regulation
AGC_PKC_PKCi_PRKCI_ST	Q7KZI7	MARK2	P41743	PRKCI	T467	P470S	470	Missense	distal	3	no	8.882	8.357	EPSD	COSMIC	6.376	Down-regulation
AGC_PKC_PKCi_PRKCI_ST	Q7KZI7	MARK2	P41743	PRKCI	T467	E462D	462	Missense	distal	-5	no	8.882	6.845	EPSD	COSMIC	6.376	Down-regulation
AGC_PKC_PKCi_PRKCI_ST	Q7KZI7	MARK2	P41743	PRKCI	T467	K464N	464	Missense	distal	-3	no	8.882	8.073	EPSD	COSMIC	6.376	Down-regulation
AGC_PKC_PKCi_PRKCI_ST	Q7KZI7	MARK2	P41743	PRKCI	S505	M508I	508	Missense	distal	3	no	6.311	6.438	EPSD	COSMIC	6.376	Gain
AGC_PKC_PKCi_PRKCI_ST	Q7KZI7	MARK2	P41743	PRKCI	S533	P540L	540	Missense	distal	7	no	8.460	8.444	EPSD	COSMIC	6.376	Down-regulation
AGC_PKC_PKCi_PRKCI_ST	Q7KZI7	MARK2	P41743	PRKCI	S533	R526W	526	Missense	distal	-7	no	8.460	9.811	EPSD	COSMIC	6.376	Up-regulation
AGC_PKC_PKCi_PRKCI_ST	Q7KZI7	MARK2	P41743	PRKCI	S533	P527S	527	Missense	distal	-6	no	8.460	7.851	EPSD	COSMIC	6.376	Down-regulation
AGC_PKC_PKCi_PRKCI_ST	Q7KZI7	MARK2	P41743	PRKCI	S533	P527Q	527	Missense	distal	-6	no	8.460	7.860	EPSD	COSMIC	6.376	Down-regulation
AGC_PKC_PKCi_PRKCI_ST	Q7KZI7	MARK2	P41743	PRKCI	S533	A536V	536	Missense	distal	3	no	8.460	8.717	EPSD	COSMIC	6.376	Up-regulation
AGC_PKC_PKCi_PRKCI_ST	Q7KZI7	MARK2	P41743	PRKCI	S533	S535F	535	Missense	proximal	2	no	8.460	7.106	EPSD	COSMIC	6.376	Down-regulation
AGC_PKC_PKCi_PRKCI_ST	Q7KZI7	MARK2	P41743	PRKCI	S569	P566L	566	Missense	distal	-3	no	6.087	6.519	EPSD	COSMIC	6.376	Gain
AGC_PKC_PKCi_PRKCI_ST	Q7KZI7	MARK2	P41743	PRKCI	S571	R564H	564	Missense	distal	-7	no	5.921	6.454	EPSD	COSMIC	6.376	Gain
AGC_PKC_PKCi_PRKCI_ST	Q7KZI7	MARK2	P41743	PRKCI	S576	S569F	569	Missense	distal	-7	no	5.939	6.489	EPSD	COSMIC	6.376	Gain
AGC_PKC_PKCi_PRKCI_ST	Q7KZI7	MARK2	P41743	PRKCI	T596	R589H	589	Missense	distal	-7	no	11.061	11.594	PhosphoSitePlus	COSMIC	6.376	Up-regulation
AGC_PKC_PKCi_PRKCI_ST	Q7KZI7	MARK2	P41743	PRKCI	T596	R589L	589	Missense	distal	-7	no	11.061	12.208	PhosphoSitePlus	COSMIC	6.376	Up-regulation
AGC_PKC_PKCi_PRKCI_ST	Q7KZI7	MARK2	P41743	PRKCI	T596	R589W	589	Missense	distal	-7	no	11.061	12.412	PhosphoSitePlus	COSMIC	6.376	Up-regulation
AGC_PKC_PKCi_PRKCI_ST	Q7KZI7	MARK2	P41743	PRKCI	T596	R594H	594	Missense	proximal	-2	no	11.061	10.677	PhosphoSitePlus	COSMIC	6.376	Down-regulation
AGC_PKC_PKCi_PRKCI_ST	Q7KZI7	MARK2	P41743	PRKCI	T596	R603Q	603	Missense	distal	7	no	11.061	10.976	PhosphoSitePlus	COSMIC	6.376	Down-regulation
AGC_PKC_PKCi_PRKCI_ST	Q7KZI7	MARK2	P41743	PRKCI	T596	R594L	594	Missense	proximal	-2	no	11.061	10.145	PhosphoSitePlus	COSMIC	6.376	Down-regulation
AGC_PKC_PKCi_PRKCI_ST	Q7KZI7	MARK2	P41743	PRKCI	T596	R594C	594	Missense	proximal	-2	no	11.061	9.909	PhosphoSitePlus	COSMIC	6.376	Down-regulation
AGC_PKC_PKCi_PRKCI_ST	Q7KZI7	MARK2	P41743	PRKCI	T667	E660Q	660	Missense	distal	-7	no	9.657	9.345	EPSD	COSMIC	6.376	Down-regulation
AGC_PKC_PKCi_PRKCI_ST	Q7KZI7	MARK2	P41743	PRKCI	T667	R664Q	664	Missense	distal	-3	no	9.657	7.980	EPSD	COSMIC	6.376	Down-regulation
AGC_PKC_PKCi_PRKCI_ST	Q7KZI7	MARK2	P41743	PRKCI	T667	R669L	669	Missense	proximal	2	no	9.657	7.332	EPSD	COSMIC	6.376	Down-regulation
AGC_PKC_PKCi_PRKCI_ST	Q7KZI7	MARK2	P41743	PRKCI	T667	E666G	666	Missense	proximal	-1	no	9.657	9.438	EPSD	COSMIC	6.376	Down-regulation
AGC_PKC_PKCi_PRKCI_ST	Q7KZI7	MARK2	P41743	PRKCI	S692	R686L	686	Missense	distal	-6	no	5.496	6.602	EPSD	COSMIC	6.376	Gain
AGC_PKC_PKCi_PRKCI_ST	Q7KZI7	MARK2	P41743	PRKCI	S759	R757Q	757	Missense	proximal	-2	no	7.793	7.338	EPSD	COSMIC	6.376	Down-regulation
AGC_PKC_PKCi_PRKCI_ST	Q7KZI7	MARK2	P41743	PRKCI	S759	S759L	759	Missense	central	0	yes	7.793	0.000	EPSD	COSMIC	6.376	Loss
AGC_PKC_PKCi_PRKCI_ST	Q7KZI7	MARK2	P41743	PRKCI	S759	L755Q	755	Missense	distal	-4	no	7.793	7.971	EPSD	COSMIC	6.376	Up-regulation
AGC_PKC_PKCi_PRKCI_ST	Q7KZI7	MARK2	P41743	PRKCI	S759	C753Y	753	Missense	distal	-6	no	7.793	7.288	EPSD	COSMIC	6.376	Down-regulation
AGC_PKC_PKCi_PRKCI_ST	Q7KZI7	MARK2	P41743	PRKCI	S759	S759F	759	Missense	central	0	yes	7.793	0.000	EPSD	COSMIC	6.376	Loss
AGC_PKC_PKCi_PRKCI_ST	Q7KZI7	MARK2	P41743	PRKCI	S759	R757W	757	Missense	proximal	-2	no	7.793	6.655	EPSD	COSMIC	6.376	Down-regulation
AGC_PKC_PKCi_PRKCI_ST	Q7KZI7	MARK2	P41743	PRKCI	S759	G762R	762	Missense	distal	3	no	7.793	7.068	EPSD	COSMIC	6.376	Down-regulation
AGC_PKC_PKCi_PRKCI_ST	Q7KZI7	MARK2	P41743	PRKCI	S769	R767Q	767	Missense	proximal	-2	no	8.015	7.560	EPSD	COSMIC	6.376	Down-regulation
AGC_PKC_PKCi_PRKCI_ST	Q7KZI7	MARK2	P41743	PRKCI	S769	G762R	762	Missense	distal	-7	no	8.015	6.794	EPSD	COSMIC	6.376	Down-regulation
AGC_PKC_PKCi_PRKCI_ST	Q4VCS5	AMOT	P41743	PRKCI	S175	Q168H	168	Missense	distal	-7	no	6.276	6.479	EPSD	COSMIC	6.376	Gain
AGC_PKC_PKCi_PRKCI_ST	Q4VCS5	AMOT	P41743	PRKCI	S328	S328F	328	Missense	central	0	yes	6.565	0.000	EPSD	COSMIC	6.376	Loss
AGC_PKC_PKCi_PRKCI_ST	Q4VCS5	AMOT	P41743	PRKCI	S328	R330H	330	Missense	proximal	2	no	6.565	5.645	EPSD	COSMIC	6.376	Loss
AGC_PKC_PKCi_PRKCI_ST	Q4VCS5	AMOT	P41743	PRKCI	T536	L540I	540	Missense	distal	4	no	7.335	7.444	PhosphoSitePlus;EPSD	COSMIC	6.376	Up-regulation
AGC_PKC_PKCi_PRKCI_ST	Q4VCS5	AMOT	P41743	PRKCI	S538	L540I	540	Missense	proximal	2	no	8.288	8.006	EPSD;PhosphoSitePlus	COSMIC	6.376	Down-regulation
AGC_PKC_PKCi_PRKCI_ST	Q4VCS5	AMOT	P41743	PRKCI	T750	K749N	749	Missense	proximal	-1	no	9.318	9.081	EPSD;PhosphoSitePlus	COSMIC	6.376	Down-regulation
AGC_PKC_PKCi_PRKCI_ST	Q4VCS5	AMOT	P41743	PRKCI	T750	E757A	757	Missense	distal	7	no	9.318	9.339	EPSD;PhosphoSitePlus	COSMIC	6.376	Up-regulation
AGC_PKC_PKCi_PRKCI_ST	Q4VCS5	AMOT	P41743	PRKCI	T750	I748V	748	Missense	proximal	-2	no	9.318	9.369	EPSD;PhosphoSitePlus	COSMIC	6.376	Up-regulation
AGC_PKC_PKCi_PRKCI_ST	Q4VCS5	AMOT	P41743	PRKCI	S855	S855P	855	Missense	central	0	yes	6.852	0.000	EPSD	COSMIC	6.376	Loss
AGC_PKC_PKCi_PRKCI_ST	Q4VCS5	AMOT	P41743	PRKCI	S855	L851V	851	Missense	distal	-4	no	6.852	6.765	EPSD	COSMIC;GDSC;CCLE	6.376	Down-regulation
AGC_PKC_PKCi_PRKCI_ST	P08151	GLI1	P41743	PRKCI	S86	S84F	84	Missense	proximal	-2	no	8.494	8.061	EPSD	COSMIC	6.376	Down-regulation
AGC_PKC_PKCi_PRKCI_ST	P08151	GLI1	P41743	PRKCI	S86	S92N	92	Missense	distal	6	no	8.494	8.418	EPSD	COSMIC	6.376	Down-regulation
AGC_PKC_PKCi_PRKCI_ST	P08151	GLI1	P41743	PRKCI	S86	L88M	88	Missense	proximal	2	no	8.494	8.941	EPSD	COSMIC	6.376	Up-regulation
AGC_PKC_PKCi_PRKCI_ST	P08151	GLI1	P41743	PRKCI	S201	P194L	194	Missense	distal	-7	no	8.249	8.462	EPSD	COSMIC	6.376	Up-regulation
AGC_PKC_PKCi_PRKCI_ST	P08151	GLI1	P41743	PRKCI	S201	M199V	199	Missense	proximal	-2	no	8.249	8.008	EPSD	COSMIC	6.376	Down-regulation
AGC_PKC_PKCi_PRKCI_ST	P08151	GLI1	P41743	PRKCI	S201	P194R	194	Missense	distal	-7	no	8.249	7.315	EPSD	COSMIC	6.376	Down-regulation
AGC_PKC_PKCi_PRKCI_ST	P08151	GLI1	P41743	PRKCI	S201	Q208L	208	Missense	distal	7	no	8.249	8.165	EPSD	COSMIC;GDSC	6.376	Down-regulation
AGC_PKC_PKCi_PRKCI_ST	P08151	GLI1	P41743	PRKCI	S201	D198Y	198	Missense	distal	-3	no	8.249	8.317	EPSD	COSMIC	6.376	Up-regulation
AGC_PKC_PKCi_PRKCI_ST	P08151	GLI1	P41743	PRKCI	S201	Q208R	208	Missense	distal	7	no	8.249	8.334	EPSD	COSMIC	6.376	Up-regulation
AGC_PKC_PKCi_PRKCI_ST	P08151	GLI1	P41743	PRKCI	S201	G197A	197	Missense	distal	-4	no	8.249	8.427	EPSD	COSMIC	6.376	Up-regulation
AGC_PKC_PKCi_PRKCI_ST	P08151	GLI1	P41743	PRKCI	S243	D247Y	247	Missense	distal	4	no	12.133	12.062	EPSD;PhosphoSitePlus	COSMIC	6.376	Down-regulation
AGC_PKC_PKCi_PRKCI_ST	P08151	GLI1	P41743	PRKCI	S243	D247N	247	Missense	distal	4	no	12.133	12.072	EPSD;PhosphoSitePlus	COSMIC	6.376	Down-regulation
AGC_PKC_PKCi_PRKCI_ST	P08151	GLI1	P41743	PRKCI	S243	Q244H	244	Missense	proximal	1	no	12.133	10.938	EPSD;PhosphoSitePlus	COSMIC	6.376	Down-regulation
AGC_PKC_PKCi_PRKCI_ST	P08151	GLI1	P41743	PRKCI	S243	D240G	240	Missense	distal	-3	no	12.133	12.812	EPSD;PhosphoSitePlus	COSMIC	6.376	Up-regulation
AGC_PKC_PKCi_PRKCI_ST	P08151	GLI1	P41743	PRKCI	T296	R293H	293	Missense	distal	-3	no	8.752	6.915	EPSD	COSMIC	6.376	Down-regulation
AGC_PKC_PKCi_PRKCI_ST	P08151	GLI1	P41743	PRKCI	T296	E298V	298	Missense	proximal	2	no	8.752	6.521	EPSD	COSMIC	6.376	Down-regulation
AGC_PKC_PKCi_PRKCI_ST	P08151	GLI1	P41743	PRKCI	T296	R293C	293	Missense	distal	-3	no	8.752	4.680	EPSD	COSMIC	6.376	Loss
AGC_PKC_PKCi_PRKCI_ST	P08151	GLI1	P41743	PRKCI	T304	G307W	307	Missense	distal	3	no	10.879	11.111	PhosphoSitePlus;EPSD	COSMIC	6.376	Up-regulation
AGC_PKC_PKCi_PRKCI_ST	P08151	GLI1	P41743	PRKCI	T304	E306K	306	Missense	proximal	2	no	10.879	10.754	PhosphoSitePlus;EPSD	COSMIC	6.376	Down-regulation
AGC_PKC_PKCi_PRKCI_ST	P08151	GLI1	P41743	PRKCI	T304	E298V	298	Missense	distal	-6	no	10.879	10.825	PhosphoSitePlus;EPSD	COSMIC	6.376	Down-regulation
AGC_PKC_PKCi_PRKCI_ST	P08151	GLI1	P41743	PRKCI	T304	G307E	307	Missense	distal	3	no	10.879	10.390	PhosphoSitePlus;EPSD	COSMIC	6.376	Down-regulation
AGC_PKC_PKCi_PRKCI_ST	P08151	GLI1	P41743	PRKCI	S602	G599R	599	Missense	distal	-3	no	4.903	6.838	EPSD	COSMIC	6.376	Gain
AGC_PKC_PKCi_PRKCI_ST	P08151	GLI1	P41743	PRKCI	S937	R940Q	940	Missense	distal	3	no	6.947	7.132	EPSD	COSMIC	6.376	Up-regulation
AGC_PKC_PKCi_PRKCI_ST	P08151	GLI1	P41743	PRKCI	S937	R940W	940	Missense	distal	3	no	6.947	7.904	EPSD	COSMIC	6.376	Up-regulation
AGC_PKC_PKCi_PRKCI_ST	P08151	GLI1	P41743	PRKCI	S937	L931R	931	Missense	distal	-6	no	6.947	5.841	EPSD	COSMIC	6.376	Loss
AGC_PKC_PKCi_PRKCI_ST	P08151	GLI1	P41743	PRKCI	S937	G933D	933	Missense	distal	-4	no	6.947	6.920	EPSD	COSMIC	6.376	Down-regulation
AGC_PKC_PKCi_PRKCI_ST	P08151	GLI1	P41743	PRKCI	S937	G932E	932	Missense	distal	-5	no	6.947	9.084	EPSD	COSMIC;CCLE	6.376	Up-regulation
AGC_PKC_PKCi_PRKCI_ST	P08151	GLI1	P41743	PRKCI	S937	R940C	940	Missense	distal	3	no	6.947	8.006	EPSD	COSMIC	6.376	Up-regulation
AGC_PKC_PKCi_PRKCI_ST	P08151	GLI1	P41743	PRKCI	S937	S934F	934	Missense	distal	-3	no	6.947	4.536	EPSD	COSMIC	6.376	Loss
AGC_PKC_PKCi_PRKCI_ST	P08151	GLI1	P41743	PRKCI	S937	A941T	941	Missense	distal	4	no	6.947	7.031	EPSD	COSMIC	6.376	Up-regulation
AGC_PKC_PKCi_PRKCI_ST	P10636	MAPT	P41743	PRKCI	S61	E62K	62	Missense	proximal	1	no	4.685	8.348	EPSD	COSMIC	6.376	Gain
AGC_PKC_PKCi_PRKCI_ST	P10636	MAPT	P41743	PRKCI	T123	V122M	122	Missense	proximal	-1	no	8.172	8.451	EPSD	COSMIC	6.376	Up-regulation
AGC_PKC_PKCi_PRKCI_ST	P10636	MAPT	P41743	PRKCI	S214	E210Q	210	Missense	distal	-4	no	10.639	10.623	EPSD	COSMIC	6.376	Down-regulation
AGC_PKC_PKCi_PRKCI_ST	P10636	MAPT	P41743	PRKCI	S214	G207E	207	Missense	distal	-7	no	10.639	10.059	EPSD	COSMIC	6.376	Down-regulation
AGC_PKC_PKCi_PRKCI_ST	P10636	MAPT	P41743	PRKCI	S341	A337T	337	Missense	distal	-4	no	6.535	6.363	EPSD	COSMIC	6.376	Loss
AGC_PKC_PKCi_PRKCI_ST	P10636	MAPT	P41743	PRKCI	S341	G343R	343	Missense	proximal	2	no	6.535	8.478	EPSD	COSMIC	6.376	Up-regulation
AGC_PKC_PKCi_PRKCI_ST	P10636	MAPT	P41743	PRKCI	S341	D345G	345	Missense	distal	4	no	6.535	6.564	EPSD	COSMIC	6.376	Up-regulation
AGC_PKC_PKCi_PRKCI_ST	P10636	MAPT	P41743	PRKCI	S341	K347N	347	Missense	distal	6	no	6.535	6.419	EPSD	COSMIC	6.376	Down-regulation
AGC_PKC_PKCi_PRKCI_ST	P10636	MAPT	P41743	PRKCI	T416	L410F	410	Missense	distal	-6	no	7.632	7.371	EPSD	COSMIC	6.376	Down-regulation
AGC_PKC_PKCi_PRKCI_ST	P10636	MAPT	P41743	PRKCI	T416	P412S	412	Missense	distal	-4	no	7.632	7.961	EPSD	COSMIC	6.376	Up-regulation
AGC_PKC_PKCi_PRKCI_ST	P10636	MAPT	P41743	PRKCI	S447	S443Y	443	Missense	distal	-4	no	6.735	6.453	EPSD	COSMIC	6.376	Down-regulation
AGC_PKC_PKCi_PRKCI_ST	P10636	MAPT	P41743	PRKCI	S447	S447P	447	Missense	central	0	yes	6.735	0.000	EPSD	COSMIC	6.376	Loss
AGC_PKC_PKCi_PRKCI_ST	P10636	MAPT	P41743	PRKCI	S447	R448Q	448	Missense	proximal	1	no	6.735	8.745	EPSD	COSMIC	6.376	Up-regulation
AGC_PKC_PKCi_PRKCI_ST	P10636	MAPT	P41743	PRKCI	T466	T466M	466	Missense	central	0	yes	6.801	0.000	EPSD	COSMIC;GDSC;CCLE	6.376	Loss
AGC_PKC_PKCi_PRKCI_ST	P10636	MAPT	P41743	PRKCI	T466	K467T	467	Missense	proximal	1	no	6.801	2.781	EPSD	COSMIC	6.376	Loss
AGC_PKC_PKCi_PRKCI_ST	P10636	MAPT	P41743	PRKCI	T470	T466M	466	Missense	distal	-4	no	9.903	9.919	EPSD	COSMIC;GDSC;CCLE	6.376	Up-regulation
AGC_PKC_PKCi_PRKCI_ST	P10636	MAPT	P41743	PRKCI	T470	K467T	467	Missense	distal	-3	no	9.903	10.071	EPSD	COSMIC	6.376	Up-regulation
AGC_PKC_PKCi_PRKCI_ST	P10636	MAPT	P41743	PRKCI	T470	P477L	477	Missense	distal	7	no	9.903	9.887	EPSD	COSMIC	6.376	Down-regulation
AGC_PKC_PKCi_PRKCI_ST	P10636	MAPT	P41743	PRKCI	T470	P477S	477	Missense	distal	7	no	9.903	10.037	EPSD	COSMIC	6.376	Up-regulation
AGC_PKC_PKCi_PRKCI_ST	P10636	MAPT	P41743	PRKCI	S531	R526H	526	Missense	distal	-5	no	8.198	6.269	EPSD	COSMIC	6.376	Loss
AGC_PKC_PKCi_PRKCI_ST	P10636	MAPT	P41743	PRKCI	S531	R528S	528	Missense	distal	-3	no	8.198	7.142	EPSD	COSMIC	6.376	Down-regulation
AGC_PKC_PKCi_PRKCI_ST	P10636	MAPT	P41743	PRKCI	S531	P530S	530	Missense	proximal	-1	no	8.198	8.252	EPSD	COSMIC	6.376	Up-regulation
AGC_PKC_PKCi_PRKCI_ST	P10636	MAPT	P41743	PRKCI	S531	P536H	536	Missense	distal	5	no	8.198	8.409	EPSD	COSMIC	6.376	Up-regulation
AGC_PKC_PKCi_PRKCI_ST	P10636	MAPT	P41743	PRKCI	S531	P535Q	535	Missense	distal	4	no	8.198	7.992	EPSD	COSMIC	6.376	Down-regulation
AGC_PKC_PKCi_PRKCI_ST	P10636	MAPT	P41743	PRKCI	T534	R528S	528	Missense	distal	-6	no	6.643	6.829	EPSD	COSMIC	6.376	Up-regulation
AGC_PKC_PKCi_PRKCI_ST	P10636	MAPT	P41743	PRKCI	T534	P530S	530	Missense	distal	-4	no	6.643	6.971	EPSD	COSMIC	6.376	Up-regulation
AGC_PKC_PKCi_PRKCI_ST	P10636	MAPT	P41743	PRKCI	T534	P536H	536	Missense	proximal	2	no	6.643	8.063	EPSD	COSMIC	6.376	Up-regulation
AGC_PKC_PKCi_PRKCI_ST	P10636	MAPT	P41743	PRKCI	T534	P535Q	535	Missense	proximal	1	no	6.643	6.694	EPSD	COSMIC	6.376	Up-regulation
AGC_PKC_PKCi_PRKCI_ST	P10636	MAPT	P41743	PRKCI	T534	E539Q	539	Missense	distal	5	no	6.643	6.832	EPSD	COSMIC	6.376	Up-regulation
AGC_PKC_PKCi_PRKCI_ST	P10636	MAPT	P41743	PRKCI	S554	S555F	555	Missense	proximal	1	no	2.275	6.703	EPSD	COSMIC	6.376	Gain
AGC_PKC_PKCi_PRKCI_ST	P10636	MAPT	P41743	PRKCI	S575	T580N	580	Missense	distal	5	no	8.591	8.394	EPSD	COSMIC	6.376	Down-regulation
AGC_PKC_PKCi_PRKCI_ST	P10636	MAPT	P41743	PRKCI	S575	G578S	578	Missense	distal	3	no	8.591	7.777	EPSD	COSMIC	6.376	Down-regulation
AGC_PKC_PKCi_PRKCI_ST	P10636	MAPT	P41743	PRKCI	S575	K571E	571	Missense	distal	-4	no	8.591	8.663	EPSD	COSMIC	6.376	Up-regulation
AGC_PKC_PKCi_PRKCI_ST	P10636	MAPT	P41743	PRKCI	S575	P568S	568	Missense	distal	-7	no	8.591	8.027	EPSD	COSMIC	6.376	Down-regulation
AGC_PKC_PKCi_PRKCI_ST	P10636	MAPT	P41743	PRKCI	S610	N613D	613	Missense	distal	3	no	9.620	10.148	EPSD	COSMIC	6.376	Up-regulation
AGC_PKC_PKCi_PRKCI_ST	P10636	MAPT	P41743	PRKCI	S610	C608W	608	Missense	proximal	-2	no	9.620	9.633	EPSD	COSMIC	6.376	Up-regulation
AGC_PKC_PKCi_PRKCI_ST	P10636	MAPT	P41743	PRKCI	S610	S610L	610	Missense	central	0	yes	9.620	0.000	EPSD	COSMIC	6.376	Loss
AGC_PKC_PKCi_PRKCI_ST	P10636	MAPT	P41743	PRKCI	S641	H647Y	647	Missense	distal	6	no	10.820	10.709	EPSD	COSMIC	6.376	Down-regulation
AGC_PKC_PKCi_PRKCI_ST	P10636	MAPT	P41743	PRKCI	S669	S669L	669	Missense	central	0	yes	11.021	0.000	EPSD	COSMIC	6.376	Loss
AGC_PKC_PKCi_PRKCI_ST	P10636	MAPT	P41743	PRKCI	S669	R666K	666	Missense	distal	-3	no	11.021	9.604	EPSD	COSMIC	6.376	Down-regulation
AGC_PKC_PKCi_PRKCI_ST	P10636	MAPT	P41743	PRKCI	S669	D662G	662	Missense	distal	-7	no	11.021	11.173	EPSD	COSMIC	6.376	Up-regulation
AGC_PKC_PKCi_PRKCI_ST	P10636	MAPT	P41743	PRKCI	S669	S673F	673	Missense	distal	4	no	11.021	10.986	EPSD	COSMIC	6.376	Down-regulation
AGC_PKC_PKCi_PRKCI_ST	P10636	MAPT	P41743	PRKCI	S669	K670N	670	Missense	proximal	1	no	11.021	6.470	EPSD	COSMIC	6.376	Down-regulation
AGC_PKC_PKCi_PRKCI_ST	P10636	MAPT	P41743	PRKCI	S669	K664N	664	Missense	distal	-5	no	11.021	9.537	EPSD	COSMIC	6.376	Down-regulation
AGC_PKC_PKCi_PRKCI_ST	P10636	MAPT	P41743	PRKCI	S669	L674Q	674	Missense	distal	5	no	11.021	11.279	EPSD	COSMIC	6.376	Up-regulation
AGC_PKC_PKCi_PRKCI_ST	P10636	MAPT	P41743	PRKCI	T694	R696H	696	Missense	proximal	2	no	7.032	6.112	EPSD	COSMIC	6.376	Loss
AGC_PKC_PKCi_PRKCI_ST	P10636	MAPT	P41743	PRKCI	T694	R696C	696	Missense	proximal	2	no	7.032	3.437	EPSD	COSMIC	6.376	Loss
AGC_PKC_PKCi_PRKCI_ST	P10636	MAPT	P41743	PRKCI	S739	G732S	732	Missense	distal	-7	no	6.466	5.615	EPSD	COSMIC	6.376	Loss
AGC_PKC_PKCi_PRKCI_ST	P10636	MAPT	P41743	PRKCI	S739	D735N	735	Missense	distal	-4	no	6.466	6.772	EPSD	COSMIC	6.376	Up-regulation
AGC_PKC_PKCi_PRKCI_ST	P10636	MAPT	P41743	PRKCI	S739	G732C	732	Missense	distal	-7	no	6.466	6.823	EPSD	COSMIC	6.376	Up-regulation
AGC_PKC_PKCi_PRKCI_ST	P10636	MAPT	P41743	PRKCI	S739	T744M	744	Missense	distal	5	no	6.466	6.502	EPSD	COSMIC	6.376	Up-regulation
AGC_PKC_PKCi_PRKCI_ST	P10636	MAPT	P41743	PRKCI	S739	A743T	743	Missense	distal	4	no	6.466	6.550	EPSD	COSMIC	6.376	Up-regulation
AGC_PKC_PKCi_PRKCI_ST	Q13464	ROCK1	P41743	PRKCI	S6	R10L	10	Missense	distal	4	no	11.443	12.008	EPSD	COSMIC	6.376	Up-regulation
AGC_PKC_PKCi_PRKCI_ST	Q13464	ROCK1	P41743	PRKCI	S6	T9A	9	Missense	distal	3	no	11.443	11.561	EPSD	COSMIC	6.376	Up-regulation
AGC_PKC_PKCi_PRKCI_ST	Q13464	ROCK1	P41743	PRKCI	T9	R10L	10	Missense	proximal	1	no	6.448	7.691	EPSD	COSMIC	6.376	Up-regulation
AGC_PKC_PKCi_PRKCI_ST	Q13464	ROCK1	P41743	PRKCI	T9	T9A	9	Missense	central	0	yes	6.448	0.000	EPSD	COSMIC	6.376	Loss
AGC_PKC_PKCi_PRKCI_ST	Q13464	ROCK1	P41743	PRKCI	S633	V638G	638	Missense	distal	5	no	12.099	12.171	EPSD	COSMIC	6.376	Up-regulation
AGC_PKC_PKCi_PRKCI_ST	Q13464	ROCK1	P41743	PRKCI	T1024	Q1025R	1025	Missense	proximal	1	no	8.876	6.866	EPSD;PhosphoSitePlus	COSMIC	6.376	Down-regulation
AGC_PKC_PKCi_PRKCI_ST	Q13464	ROCK1	P41743	PRKCI	T1180	Y1185H	1185	Missense	distal	5	no	9.370	9.569	EPSD	COSMIC	6.376	Up-regulation
AGC_PKC_PKCi_PRKCI_ST	Q13464	ROCK1	P41743	PRKCI	T1331	T1331M	1331	Missense	central	0	yes	6.613	0.000	EPSD	COSMIC	6.376	Loss
AGC_PKC_PKCi_PRKCI_ST	Q13464	ROCK1	P41743	PRKCI	S1333	T1331M	1331	Missense	proximal	-2	no	6.478	6.150	EPSD;PhosphoSitePlus	COSMIC	6.376	Loss
AGC_PKC_PKCi_PRKCI_ST	Q13464	ROCK1	P41743	PRKCI	S1341	S1341F	1341	Missense	central	0	yes	8.401	0.000	EPSD;PhosphoSitePlus	COSMIC	6.376	Loss
AGC_PKC_PKCi_PRKCI_ST	Q92934	BAD	P41743	PRKCI	S25	A27T	27	Missense	proximal	2	no	8.959	9.582	EPSD	COSMIC;GDSC;CCLE	6.376	Up-regulation
AGC_PKC_PKCi_PRKCI_ST	Q92934	BAD	P41743	PRKCI	S75	A78E	78	Missense	distal	3	no	9.961	9.869	PhosphoSitePlus;EPSD	COSMIC	6.376	Down-regulation
AGC_PKC_PKCi_PRKCI_ST	Q92934	BAD	P41743	PRKCI	S99	P102L	102	Missense	distal	3	no	9.931	10.134	EPSD;PhosphoSitePlus	COSMIC	6.376	Up-regulation
AGC_PKC_PKCi_PRKCI_ST	Q92934	BAD	P41743	PRKCI	S99	S97P	97	Missense	proximal	-2	no	9.931	9.700	EPSD;PhosphoSitePlus	COSMIC	6.376	Down-regulation
AGC_PKC_PKCi_PRKCI_ST	Q92934	BAD	P41743	PRKCI	S99	R98H	98	Missense	proximal	-1	no	9.931	9.641	EPSD;PhosphoSitePlus	COSMIC	6.376	Down-regulation
AGC_PKC_PKCi_PRKCI_ST	Q92934	BAD	P41743	PRKCI	S99	P101S	101	Missense	proximal	2	no	9.931	10.622	EPSD;PhosphoSitePlus	COSMIC	6.376	Up-regulation
AGC_PKC_PKCi_PRKCI_ST	Q92934	BAD	P41743	PRKCI	S118	S124F	124	Missense	distal	6	no	7.851	7.724	EPSD;PhosphoSitePlus	COSMIC	6.376	Down-regulation
AGC_PKC_PKCi_PRKCI_ST	Q13118	KLF10	P41743	PRKCI	S342	P343L	343	Missense	proximal	1	no	8.185	7.470	EPSD	COSMIC	6.376	Down-regulation
AGC_PKC_PKCi_PRKCI_ST	Q13118	KLF10	P41743	PRKCI	S342	P343S	343	Missense	proximal	1	no	8.185	5.137	EPSD	COSMIC	6.376	Loss
AGC_PKC_PKCi_PRKCI_ST	Q13118	KLF10	P41743	PRKCI	T422	G425D	425	Missense	distal	3	no	8.101	7.871	EPSD	COSMIC;GDSC;CCLE	6.376	Down-regulation
AGC_PKC_PKCi_PRKCI_ST	Q13118	KLF10	P41743	PRKCI	T422	T424K	424	Missense	proximal	2	no	8.101	8.538	EPSD	COSMIC	6.376	Up-regulation
AGC_PKC_PKCi_PRKCI_ST	Q13118	KLF10	P41743	PRKCI	T445	R449W	449	Missense	distal	4	no	9.688	10.470	EPSD;PhosphoSitePlus	COSMIC	6.376	Up-regulation
AGC_PKC_PKCi_PRKCI_ST	P15311	EZR	P41743	PRKCI	S249	R246K	246	Missense	distal	-3	no	9.309	7.891	EPSD	COSMIC	6.376	Down-regulation
AGC_PKC_PKCi_PRKCI_ST	P15311	EZR	P41743	PRKCI	S249	K253R	253	Missense	distal	4	no	9.309	8.844	EPSD	COSMIC;CCLE	6.376	Down-regulation
AGC_PKC_PKCi_PRKCI_ST	P15311	EZR	P41743	PRKCI	T299	M305I	305	Missense	distal	6	no	6.868	6.701	EPSD	COSMIC	6.376	Down-regulation
AGC_PKC_PKCi_PRKCI_ST	P15311	EZR	P41743	PRKCI	T299	R294H	294	Missense	distal	-5	no	6.868	4.939	EPSD	COSMIC	6.376	Loss
AGC_PKC_PKCi_PRKCI_ST	P15311	EZR	P41743	PRKCI	T332	V333M	333	Missense	proximal	1	no	5.379	7.363	EPSD	COSMIC;CCLE	6.376	Gain
AGC_PKC_PKCi_PRKCI_ST	P15311	EZR	P41743	PRKCI	T332	V333L	333	Missense	proximal	1	no	5.379	7.085	EPSD	COSMIC	6.376	Gain
AGC_PKC_PKCi_PRKCI_ST	P15311	EZR	P41743	PRKCI	T358	R363K	363	Missense	distal	5	no	8.091	8.173	EPSD	COSMIC;GDSC;CCLE	6.376	Up-regulation
AGC_PKC_PKCi_PRKCI_ST	Q15910	EZH2	P41743	PRKCI	S8	G5W	5	Missense	distal	-3	no	9.834	8.153	EPSD	COSMIC	6.376	Down-regulation
AGC_PKC_PKCi_PRKCI_ST	Q15910	EZH2	P41743	PRKCI	S8	G2C	2	Missense	distal	-6	no	9.834	10.051	EPSD	COSMIC	6.376	Up-regulation
AGC_PKC_PKCi_PRKCI_ST	Q15910	EZH2	P41743	PRKCI	S8	S8F	8	Missense	central	0	yes	9.834	0.000	EPSD	COSMIC	6.376	Loss
AGC_PKC_PKCi_PRKCI_ST	Q15910	EZH2	P41743	PRKCI	S8	G2S	2	Missense	distal	-6	no	9.834	8.835	EPSD	COSMIC	6.376	Down-regulation
AGC_PKC_PKCi_PRKCI_ST	Q15910	EZH2	P41743	PRKCI	S8	V13A	13	Missense	distal	5	no	9.834	10.105	EPSD	COSMIC	6.376	Up-regulation
AGC_PKC_PKCi_PRKCI_ST	Q15910	EZH2	P41743	PRKCI	S8	Q3L	3	Missense	distal	-5	no	9.834	7.372	EPSD	COSMIC	6.376	Down-regulation
AGC_PKC_PKCi_PRKCI_ST	Q15910	EZH2	P41743	PRKCI	S8	G5R	5	Missense	distal	-3	no	9.834	11.768	EPSD	COSMIC	6.376	Up-regulation
AGC_PKC_PKCi_PRKCI_ST	Q15910	EZH2	P41743	PRKCI	S21	R16Q	16	Missense	distal	-5	no	11.389	10.535	EPSD	COSMIC;GDSC;CCLE	6.376	Down-regulation
AGC_PKC_PKCi_PRKCI_ST	Q15910	EZH2	P41743	PRKCI	S21	Q28R	28	Missense	distal	7	no	11.389	11.474	EPSD	COSMIC	6.376	Up-regulation
AGC_PKC_PKCi_PRKCI_ST	Q15910	EZH2	P41743	PRKCI	S21	L26P	26	Missense	distal	5	no	11.389	11.323	EPSD	COSMIC	6.376	Down-regulation
AGC_PKC_PKCi_PRKCI_ST	Q15910	EZH2	P41743	PRKCI	S21	R18H	18	Missense	distal	-3	no	11.389	9.552	EPSD	COSMIC	6.376	Down-regulation
AGC_PKC_PKCi_PRKCI_ST	Q15910	EZH2	P41743	PRKCI	S21	R16W	16	Missense	distal	-5	no	11.389	6.745	EPSD	COSMIC	6.376	Down-regulation
AGC_PKC_PKCi_PRKCI_ST	Q15910	EZH2	P41743	PRKCI	T302	H297R	297	Missense	distal	-5	no	4.632	6.561	EPSD	COSMIC	6.376	Gain
AGC_PKC_PKCi_PRKCI_ST	Q15910	EZH2	P41743	PRKCI	T305	H300R	300	Missense	distal	-5	no	5.236	7.165	EPSD	COSMIC	6.376	Gain
AGC_PKC_PKCi_PRKCI_ST	Q15910	EZH2	P41743	PRKCI	T345	R342W	342	Missense	distal	-3	no	10.081	6.466	EPSD;PhosphoSitePlus	COSMIC	6.376	Down-regulation
AGC_PKC_PKCi_PRKCI_ST	Q15910	EZH2	P41743	PRKCI	T345	R349C	349	Missense	distal	4	no	10.081	10.962	EPSD;PhosphoSitePlus	COSMIC	6.376	Up-regulation
AGC_PKC_PKCi_PRKCI_ST	Q15910	EZH2	P41743	PRKCI	T345	R342Q	342	Missense	distal	-3	no	10.081	8.403	EPSD;PhosphoSitePlus	COSMIC;CCLE	6.376	Down-regulation
AGC_PKC_PKCi_PRKCI_ST	Q15910	EZH2	P41743	PRKCI	T345	R342L	342	Missense	distal	-3	no	10.081	7.188	EPSD;PhosphoSitePlus	COSMIC	6.376	Down-regulation
AGC_PKC_PKCi_PRKCI_ST	Q15910	EZH2	P41743	PRKCI	T345	A340T	340	Missense	distal	-5	no	10.081	11.281	EPSD;PhosphoSitePlus	COSMIC;CCLE	6.376	Up-regulation
AGC_PKC_PKCi_PRKCI_ST	Q15910	EZH2	P41743	PRKCI	T345	E341K	341	Missense	distal	-4	no	10.081	10.009	EPSD;PhosphoSitePlus	COSMIC	6.376	Down-regulation
AGC_PKC_PKCi_PRKCI_ST	Q15910	EZH2	P41743	PRKCI	T345	L338F	338	Missense	distal	-7	no	10.081	9.854	EPSD;PhosphoSitePlus	COSMIC	6.376	Down-regulation
AGC_PKC_PKCi_PRKCI_ST	Q15910	EZH2	P41743	PRKCI	S408	E409K	409	Missense	proximal	1	no	5.484	9.147	EPSD	COSMIC	6.376	Gain
AGC_PKC_PKCi_PRKCI_ST	Q15910	EZH2	P41743	PRKCI	T487	A482T	482	Missense	distal	-5	no	9.458	10.658	PhosphoSitePlus;EPSD	COSMIC	6.376	Up-regulation
AGC_PKC_PKCi_PRKCI_ST	Q15910	EZH2	P41743	PRKCI	T487	P488S	488	Missense	proximal	1	no	9.458	6.410	PhosphoSitePlus;EPSD	COSMIC	6.376	Down-regulation
AGC_PKC_PKCi_PRKCI_ST	Q15910	EZH2	P41743	PRKCI	T487	R494S	494	Missense	distal	7	no	9.458	9.440	PhosphoSitePlus;EPSD	COSMIC	6.376	Down-regulation
AGC_PKC_PKCi_PRKCI_ST	Q15910	EZH2	P41743	PRKCI	T487	R494K	494	Missense	distal	7	no	9.458	9.364	PhosphoSitePlus;EPSD	COSMIC	6.376	Down-regulation
AGC_PKC_PKCi_PRKCI_ST	Q15910	EZH2	P41743	PRKCI	T487	P481S	481	Missense	distal	-6	no	9.458	8.849	PhosphoSitePlus;EPSD	COSMIC	6.376	Down-regulation
AGC_PKC_PKCi_PRKCI_ST	Q15910	EZH2	P41743	PRKCI	T487	P488A	488	Missense	proximal	1	no	9.458	7.756	PhosphoSitePlus;EPSD	COSMIC	6.376	Down-regulation
AGC_PKC_PKCi_PRKCI_ST	Q15910	EZH2	P41743	PRKCI	T487	K491R	491	Missense	distal	4	no	9.458	8.993	PhosphoSitePlus;EPSD	COSMIC	6.376	Down-regulation
AGC_PKC_PKCi_PRKCI_ST	Q15910	EZH2	P41743	PRKCI	S690	R685S	685	Missense	distal	-5	no	11.100	8.611	EPSD;PhosphoSitePlus	COSMIC	6.376	Down-regulation
AGC_PKC_PKCi_PRKCI_ST	Q15910	EZH2	P41743	PRKCI	S690	R685C	685	Missense	distal	-5	no	11.100	6.070	EPSD;PhosphoSitePlus	COSMIC	6.376	Loss
AGC_PKC_PKCi_PRKCI_ST	Q15910	EZH2	P41743	PRKCI	S690	K683N	683	Missense	distal	-7	no	11.100	10.906	EPSD;PhosphoSitePlus	COSMIC	6.376	Down-regulation
AGC_PKC_PKCi_PRKCI_ST	Q15910	EZH2	P41743	PRKCI	S690	S690P	690	Missense	central	0	yes	11.100	0.000	EPSD;PhosphoSitePlus	COSMIC	6.376	Loss
AGC_PKC_PKCi_PRKCI_ST	Q15910	EZH2	P41743	PRKCI	S690	N688T	688	Missense	proximal	-2	no	11.100	11.516	EPSD;PhosphoSitePlus	COSMIC	6.376	Up-regulation
AGC_PKC_PKCi_PRKCI_ST	Q15910	EZH2	P41743	PRKCI	S690	H689Y	689	Missense	proximal	-1	no	11.100	11.027	EPSD;PhosphoSitePlus	COSMIC	6.376	Down-regulation
AGC_PKC_PKCi_PRKCI_ST	Q15910	EZH2	P41743	PRKCI	S690	H689R	689	Missense	proximal	-1	no	11.100	11.390	EPSD;PhosphoSitePlus	COSMIC	6.376	Up-regulation
AGC_PKC_PKCi_PRKCI_ST	Q15910	EZH2	P41743	PRKCI	S690	N692D	692	Missense	proximal	2	no	11.100	10.163	EPSD;PhosphoSitePlus	COSMIC	6.376	Down-regulation
AGC_PKC_PKCi_PRKCI_ST	Q15910	EZH2	P41743	PRKCI	S690	N688I	688	Missense	proximal	-2	no	11.100	10.895	EPSD;PhosphoSitePlus	COSMIC	6.376	Down-regulation
AGC_PKC_PKCi_PRKCI_ST	Q15910	EZH2	P41743	PRKCI	S690	S690I	690	Missense	central	0	yes	11.100	0.000	EPSD;PhosphoSitePlus	COSMIC	6.376	Loss
AGC_PKC_PKCi_PRKCI_ST	P08047	SP1	P41743	PRKCI	S56	S59Y	59	Missense	distal	3	no	6.243	6.731	EPSD	COSMIC	6.376	Gain
AGC_PKC_PKCi_PRKCI_ST	P08047	SP1	P41743	PRKCI	S59	S59Y	59	Missense	central	0	yes	12.403	0.000	PhosphoSitePlus	COSMIC	6.376	Loss
AGC_PKC_PKCi_PRKCI_ST	P08047	SP1	P41743	PRKCI	S81	Q86R	86	Missense	distal	5	no	6.769	6.783	EPSD	COSMIC	6.376	Up-regulation
AGC_PKC_PKCi_PRKCI_ST	P08047	SP1	P41743	PRKCI	S81	N79K	79	Missense	proximal	-2	no	6.769	7.173	EPSD	COSMIC	6.376	Up-regulation
AGC_PKC_PKCi_PRKCI_ST	P08047	SP1	P41743	PRKCI	S81	P84L	84	Missense	distal	3	no	6.769	6.972	EPSD	COSMIC	6.376	Up-regulation
AGC_PKC_PKCi_PRKCI_ST	P08047	SP1	P41743	PRKCI	S101	A97V	97	Missense	distal	-4	no	10.136	9.777	EPSD	COSMIC	6.376	Down-regulation
AGC_PKC_PKCi_PRKCI_ST	P08047	SP1	P41743	PRKCI	S101	A104V	104	Missense	distal	3	no	10.136	10.392	EPSD	COSMIC	6.376	Up-regulation
AGC_PKC_PKCi_PRKCI_ST	P08047	SP1	P41743	PRKCI	S101	T98A	98	Missense	distal	-3	no	10.136	9.800	EPSD	COSMIC;GDSC;CCLE	6.376	Down-regulation
AGC_PKC_PKCi_PRKCI_ST	P08047	SP1	P41743	PRKCI	T679	Q674H	674	Missense	distal	-5	no	8.519	7.444	EPSD	COSMIC	6.376	Down-regulation
AGC_PKC_PKCi_PRKCI_ST	P08047	SP1	P41743	PRKCI	T679	R678H	678	Missense	proximal	-1	no	8.519	8.229	EPSD	COSMIC	6.376	Down-regulation
AGC_PKC_PKCi_PRKCI_ST	P08047	SP1	P41743	PRKCI	S702	H700Y	700	Missense	proximal	-2	no	11.514	11.306	EPSD	COSMIC	6.376	Down-regulation
AGC_PKC_PKCi_PRKCI_ST	Q14247	CTTN	P41743	PRKCI	T145	Q142H	142	Missense	distal	-3	no	7.911	7.752	EPSD	COSMIC	6.376	Down-regulation
AGC_PKC_PKCi_PRKCI_ST	Q14247	CTTN	P41743	PRKCI	T145	G143W	143	Missense	proximal	-2	no	7.911	7.414	EPSD	COSMIC	6.376	Down-regulation
AGC_PKC_PKCi_PRKCI_ST	Q14247	CTTN	P41743	PRKCI	S150	G143W	143	Missense	distal	-7	no	11.991	12.120	EPSD	COSMIC	6.376	Up-regulation
AGC_PKC_PKCi_PRKCI_ST	Q14247	CTTN	P41743	PRKCI	S150	Y154C	154	Missense	distal	4	no	11.991	12.316	EPSD	COSMIC;CCLE	6.376	Up-regulation
AGC_PKC_PKCi_PRKCI_ST	Q14247	CTTN	P41743	PRKCI	S187	D190N	190	Missense	distal	3	no	13.989	13.461	EPSD	COSMIC	6.376	Down-regulation
AGC_PKC_PKCi_PRKCI_ST	Q14247	CTTN	P41743	PRKCI	S192	D190N	190	Missense	proximal	-2	no	6.786	6.752	EPSD	COSMIC	6.376	Down-regulation
AGC_PKC_PKCi_PRKCI_ST	Q14247	CTTN	P41743	PRKCI	S224	S224F	224	Missense	central	0	yes	8.299	0.000	EPSD	COSMIC	6.376	Loss
AGC_PKC_PKCi_PRKCI_ST	Q14247	CTTN	P41743	PRKCI	S261	S261F	261	Missense	central	0	yes	10.502	0.000	PhosphoSitePlus	COSMIC	6.376	Loss
AGC_PKC_PKCi_PRKCI_ST	Q14247	CTTN	P41743	PRKCI	S282	R279W	279	Missense	distal	-3	no	6.776	3.162	EPSD	COSMIC	6.376	Loss
AGC_PKC_PKCi_PRKCI_ST	Q14247	CTTN	P41743	PRKCI	S282	F287L	287	Missense	distal	5	no	6.776	6.668	EPSD	COSMIC	6.376	Down-regulation
AGC_PKC_PKCi_PRKCI_ST	Q14247	CTTN	P41743	PRKCI	S282	S277L	277	Missense	distal	-5	no	6.776	5.950	EPSD	COSMIC	6.376	Loss
AGC_PKC_PKCi_PRKCI_ST	P49757	NUMB	P41743	PRKCI	S7	R5W	5	Missense	proximal	-2	no	11.823	10.684	EPSD;PhosphoSitePlus	COSMIC	6.376	Down-regulation
AGC_PKC_PKCi_PRKCI_ST	P49757	NUMB	P41743	PRKCI	S7	L4V	4	Missense	distal	-3	no	11.823	11.055	EPSD;PhosphoSitePlus	COSMIC	6.376	Down-regulation
AGC_PKC_PKCi_PRKCI_ST	P49757	NUMB	P41743	PRKCI	S7	S7N	7	Missense	central	0	yes	11.823	0.000	EPSD;PhosphoSitePlus	COSMIC	6.376	Loss
AGC_PKC_PKCi_PRKCI_ST	P49757	NUMB	P41743	PRKCI	S194	R196H	196	Missense	proximal	2	no	7.063	6.143	EPSD	COSMIC;GDSC;CCLE	6.376	Loss
AGC_PKC_PKCi_PRKCI_ST	P49757	NUMB	P41743	PRKCI	S194	T190S	190	Missense	distal	-4	no	7.063	7.235	EPSD	COSMIC	6.376	Up-regulation
AGC_PKC_PKCi_PRKCI_ST	P49757	NUMB	P41743	PRKCI	S194	T188P	188	Missense	distal	-6	no	7.063	7.173	EPSD	COSMIC	6.376	Up-regulation
AGC_PKC_PKCi_PRKCI_ST	P49757	NUMB	P41743	PRKCI	S276	P281S	281	Missense	distal	5	no	8.385	8.365	EPSD;PhosphoSitePlus	COSMIC	6.376	Down-regulation
AGC_PKC_PKCi_PRKCI_ST	P49757	NUMB	P41743	PRKCI	S276	P281H	281	Missense	distal	5	no	8.385	8.596	EPSD;PhosphoSitePlus	COSMIC	6.376	Up-regulation
AGC_PKC_PKCi_PRKCI_ST	P49757	NUMB	P41743	PRKCI	S276	G275D	275	Missense	proximal	-1	no	8.385	8.470	EPSD;PhosphoSitePlus	COSMIC	6.376	Up-regulation
AGC_PKC_PKCi_PRKCI_ST	P49757	NUMB	P41743	PRKCI	S276	R278P	278	Missense	proximal	2	no	8.385	6.045	EPSD;PhosphoSitePlus	COSMIC	6.376	Loss
AGC_PKC_PKCi_PRKCI_ST	P49757	NUMB	P41743	PRKCI	S438	P437L	437	Missense	proximal	-1	no	9.008	8.965	EPSD	COSMIC	6.376	Down-regulation
AGC_PKC_PKCi_PRKCI_ST	P49757	NUMB	P41743	PRKCI	S438	R435P	435	Missense	distal	-3	no	9.008	5.683	EPSD	COSMIC	6.376	Loss
AGC_PKC_PKCi_PRKCI_ST	P49757	NUMB	P41743	PRKCI	S438	R435H	435	Missense	distal	-3	no	9.008	7.171	EPSD	COSMIC	6.376	Down-regulation
AGC_PKC_PKCi_PRKCI_ST	P49757	NUMB	P41743	PRKCI	S438	A431D	431	Missense	distal	-7	no	9.008	9.450	EPSD	COSMIC	6.376	Up-regulation
AGC_PKC_PKCi_PRKCI_ST	P49757	NUMB	P41743	PRKCI	S627	P633S	633	Missense	distal	6	no	12.310	12.458	EPSD	COSMIC	6.376	Up-regulation
AGC_PKC_PKCi_PRKCI_ST	P49757	NUMB	P41743	PRKCI	S627	A621V	621	Missense	distal	-6	no	12.310	12.800	EPSD	COSMIC	6.376	Up-regulation
AGC_PKC_PKCi_PRKCI_ST	P49757	NUMB	P41743	PRKCI	S634	P633S	633	Missense	proximal	-1	no	7.373	7.427	EPSD	COSMIC	6.376	Up-regulation
AGC_PKC_PKCi_PRKCI_ST	Q9UBS0	RPS6KB2	P41743	PRKCI	S15	E16K	16	Missense	proximal	1	no	5.905	9.568	EPSD	COSMIC	6.376	Gain
AGC_PKC_PKCi_PRKCI_ST	Q9UBS0	RPS6KB2	P41743	PRKCI	S379	L385M	385	Missense	distal	6	no	6.505	6.562	EPSD	COSMIC	6.376	Up-regulation
AGC_PKC_PKCi_PRKCI_ST	Q9UBS0	RPS6KB2	P41743	PRKCI	S403	G401D	401	Missense	proximal	-2	no	7.823	7.810	EPSD	COSMIC	6.376	Down-regulation
AGC_PKC_PKCi_PRKCI_ST	Q9UBS0	RPS6KB2	P41743	PRKCI	S410	R413C	413	Missense	distal	3	no	6.987	8.046	EPSD	COSMIC	6.376	Up-regulation
AGC_PKC_PKCi_PRKCI_ST	Q9UBS0	RPS6KB2	P41743	PRKCI	S410	R413H	413	Missense	distal	3	no	6.987	7.382	EPSD	COSMIC	6.376	Up-regulation
AGC_PKC_PKCi_PRKCI_ST	Q9UBS0	RPS6KB2	P41743	PRKCI	S417	P421S	421	Missense	distal	4	no	7.655	7.593	EPSD	COSMIC	6.376	Down-regulation
AGC_PKC_PKCi_PRKCI_ST	Q9UBS0	RPS6KB2	P41743	PRKCI	S417	R413C	413	Missense	distal	-4	no	7.655	7.158	EPSD	COSMIC	6.376	Down-regulation
AGC_PKC_PKCi_PRKCI_ST	Q9UBS0	RPS6KB2	P41743	PRKCI	S417	R413H	413	Missense	distal	-4	no	7.655	7.561	EPSD	COSMIC	6.376	Down-regulation
AGC_PKC_PKCi_PRKCI_ST	Q9UBS0	RPS6KB2	P41743	PRKCI	S417	P421L	421	Missense	distal	4	no	7.655	7.848	EPSD	COSMIC	6.376	Up-regulation
AGC_PKC_PKCi_PRKCI_ST	Q9UBS0	RPS6KB2	P41743	PRKCI	S417	P424L	424	Missense	distal	7	no	7.655	7.639	EPSD	COSMIC	6.376	Down-regulation
AGC_PKC_PKCi_PRKCI_ST	Q9UBS0	RPS6KB2	P41743	PRKCI	T470	S468P	468	Missense	proximal	-2	no	8.210	7.979	EPSD	COSMIC	6.376	Down-regulation
AGC_PKC_PKCi_PRKCI_ST	Q9UBS0	RPS6KB2	P41743	PRKCI	T470	P463S	463	Missense	distal	-7	no	8.210	7.646	EPSD	COSMIC	6.376	Down-regulation
AGC_PKC_PKCi_PRKCI_ST	Q9UBS0	RPS6KB2	P41743	PRKCI	T470	R477H	477	Missense	distal	7	no	8.210	8.109	EPSD	COSMIC	6.376	Down-regulation
AGC_PKC_PKCi_PRKCI_ST	Q9UBS0	RPS6KB2	P41743	PRKCI	T470	R475G	475	Missense	distal	5	no	8.210	7.719	EPSD	COSMIC	6.376	Down-regulation
AGC_PKC_PKCi_PRKCI_ST	Q9UBS0	RPS6KB2	P41743	PRKCI	T470	P467H	467	Missense	distal	-3	no	8.210	9.698	EPSD	COSMIC	6.376	Up-regulation
AGC_PKC_PKCi_PRKCI_ST	Q9UBS0	RPS6KB2	P41743	PRKCI	T470	R465H	465	Missense	distal	-5	no	8.210	6.281	EPSD	COSMIC	6.376	Loss
AGC_PKC_PKCi_PRKCI_ST	Q9UBS0	RPS6KB2	P41743	PRKCI	S473	R479H	479	Missense	distal	6	no	9.242	9.036	PhosphoSitePlus	COSMIC;CCLE	6.376	Down-regulation
AGC_PKC_PKCi_PRKCI_ST	Q9UBS0	RPS6KB2	P41743	PRKCI	S473	S468P	468	Missense	distal	-5	no	9.242	8.053	PhosphoSitePlus	COSMIC	6.376	Down-regulation
AGC_PKC_PKCi_PRKCI_ST	Q9UBS0	RPS6KB2	P41743	PRKCI	S473	P480Q	480	Missense	distal	7	no	9.242	9.309	PhosphoSitePlus	COSMIC	6.376	Up-regulation
AGC_PKC_PKCi_PRKCI_ST	Q9UBS0	RPS6KB2	P41743	PRKCI	S473	R477H	477	Missense	distal	4	no	9.242	9.535	PhosphoSitePlus	COSMIC	6.376	Up-regulation
AGC_PKC_PKCi_PRKCI_ST	Q9UBS0	RPS6KB2	P41743	PRKCI	S473	R475G	475	Missense	proximal	2	no	9.242	7.299	PhosphoSitePlus	COSMIC	6.376	Down-regulation
AGC_PKC_PKCi_PRKCI_ST	Q9UBS0	RPS6KB2	P41743	PRKCI	S473	P467H	467	Missense	distal	-6	no	9.242	8.826	PhosphoSitePlus	COSMIC	6.376	Down-regulation
AGC_PKC_PKCi_PRKCI_ST	Q6STE5	SMARCD3	P41743	PRKCI	S247	P243S	243	Missense	distal	-4	no	11.235	11.564	PhosphoSitePlus	COSMIC	6.376	Up-regulation
AGC_PKC_PKCi_PRKCI_ST	Q6STE5	SMARCD3	P41743	PRKCI	S247	G244V	244	Missense	distal	-3	no	11.235	9.509	PhosphoSitePlus	COSMIC	6.376	Down-regulation
AGC_PKC_PKCi_PRKCI_ST	P27448	MARK3	P41743	PRKCI	S45	R38W	38	Missense	distal	-7	no	5.175	6.526	EPSD	COSMIC	6.376	Gain
AGC_PKC_PKCi_PRKCI_ST	P27448	MARK3	P41743	PRKCI	S369	E370Q	370	Missense	proximal	1	no	8.164	10.436	EPSD	COSMIC	6.376	Up-regulation
AGC_PKC_PKCi_PRKCI_ST	P27448	MARK3	P41743	PRKCI	S369	E370A	370	Missense	proximal	1	no	8.164	8.683	EPSD	COSMIC	6.376	Up-regulation
AGC_PKC_PKCi_PRKCI_ST	P27448	MARK3	P41743	PRKCI	S369	E370D	370	Missense	proximal	1	no	8.164	8.131	EPSD	COSMIC;GDSC	6.376	Down-regulation
AGC_PKC_PKCi_PRKCI_ST	P27448	MARK3	P41743	PRKCI	S400	T397S	397	Missense	distal	-3	no	6.466	6.658	EPSD	COSMIC	6.376	Up-regulation
AGC_PKC_PKCi_PRKCI_ST	P27448	MARK3	P41743	PRKCI	S400	R407I	407	Missense	distal	7	no	6.466	6.283	EPSD	COSMIC	6.376	Loss
AGC_PKC_PKCi_PRKCI_ST	P27448	MARK3	P41743	PRKCI	S400	L393I	393	Missense	distal	-7	no	6.466	6.427	EPSD	COSMIC	6.376	Down-regulation
AGC_PKC_PKCi_PRKCI_ST	P27448	MARK3	P41743	PRKCI	S400	R407C	407	Missense	distal	7	no	6.466	6.215	EPSD	COSMIC	6.376	Loss
AGC_PKC_PKCi_PRKCI_ST	P27448	MARK3	P41743	PRKCI	S419	K414Q	414	Missense	distal	-5	no	6.065	6.384	EPSD	COSMIC	6.376	Gain
AGC_PKC_PKCi_PRKCI_ST	P27448	MARK3	P41743	PRKCI	S419	Q413E	413	Missense	distal	-6	no	6.065	6.858	EPSD	COSMIC	6.376	Gain
AGC_PKC_PKCi_PRKCI_ST	P27448	MARK3	P41743	PRKCI	T491	P493H	493	Missense	proximal	2	no	5.410	6.831	EPSD	COSMIC	6.376	Gain
AGC_PKC_PKCi_PRKCI_ST	P27448	MARK3	P41743	PRKCI	T507	S511N	511	Missense	distal	4	no	6.292	6.548	EPSD	COSMIC	6.376	Gain
AGC_PKC_PKCi_PRKCI_ST	P27448	MARK3	P41743	PRKCI	T564	T559S	559	Missense	distal	-5	no	9.207	8.350	PhosphoSitePlus	COSMIC	6.376	Down-regulation
AGC_PKC_PKCi_PRKCI_ST	P27448	MARK3	P41743	PRKCI	T564	S563I	563	Missense	proximal	-1	no	9.207	8.983	PhosphoSitePlus	COSMIC	6.376	Down-regulation
AGC_PKC_PKCi_PRKCI_ST	P27448	MARK3	P41743	PRKCI	T564	R557Q	557	Missense	distal	-7	no	9.207	9.536	PhosphoSitePlus	COSMIC	6.376	Up-regulation
AGC_PKC_PKCi_PRKCI_ST	P27448	MARK3	P41743	PRKCI	T564	R557L	557	Missense	distal	-7	no	9.207	10.353	PhosphoSitePlus	COSMIC	6.376	Up-regulation
AGC_PKC_PKCi_PRKCI_ST	P27448	MARK3	P41743	PRKCI	T576	G579W	579	Missense	distal	3	no	7.161	7.394	EPSD	COSMIC	6.376	Up-regulation
AGC_PKC_PKCi_PRKCI_ST	P27448	MARK3	P41743	PRKCI	S618	N616Y	616	Missense	proximal	-2	no	12.221	12.318	EPSD	COSMIC	6.376	Up-regulation
AGC_PKC_PKCi_PRKCI_ST	P27448	MARK3	P41743	PRKCI	S618	M617I	617	Missense	proximal	-1	no	12.221	11.987	EPSD	COSMIC	6.376	Down-regulation
AGC_PKC_PKCi_PRKCI_ST	P27448	MARK3	P41743	PRKCI	S618	R615I	615	Missense	distal	-3	no	12.221	8.710	EPSD	COSMIC	6.376	Down-regulation
AGC_PKC_PKCi_PRKCI_ST	P27448	MARK3	P41743	PRKCI	S724	R729W	729	Missense	distal	5	no	8.174	7.664	EPSD	COSMIC	6.376	Down-regulation
AGC_PKC_PKCi_PRKCI_ST	P27448	MARK3	P41743	PRKCI	S724	R722I	722	Missense	proximal	-2	no	8.174	7.280	EPSD	COSMIC	6.376	Down-regulation
AGC_PKC_PKCi_PRKCI_ST	P27448	MARK3	P41743	PRKCI	S724	R722S	722	Missense	proximal	-2	no	8.174	7.683	EPSD	COSMIC	6.376	Down-regulation
AGC_PKC_PKCi_PRKCI_ST	P27448	MARK3	P41743	PRKCI	S734	S734L	734	Missense	central	0	yes	8.630	0.000	EPSD	COSMIC;GDSC	6.376	Loss
AGC_PKC_PKCi_PRKCI_ST	P27448	MARK3	P41743	PRKCI	S734	R729W	729	Missense	distal	-5	no	8.630	3.986	EPSD	COSMIC	6.376	Loss
AGC_PKC_PKCi_PRKCI_ST	P27448	MARK3	P41743	PRKCI	S734	A739V	739	Missense	distal	5	no	8.630	8.358	EPSD	COSMIC	6.376	Down-regulation
AGC_PKC_PKCi_PRKCI_ST	P50613	CDK7	P41743	PRKCI	T25	D31H	31	Missense	distal	6	no	7.009	7.158	EPSD	COSMIC	6.376	Up-regulation
AGC_PKC_PKCi_PRKCI_ST	P50613	CDK7	P41743	PRKCI	T170	V173D	173	Missense	distal	3	no	8.583	8.493	PhosphoSitePlus	COSMIC	6.376	Down-regulation
AGC_PKC_PKCi_PRKCI_ST	P50613	CDK7	P41743	PRKCI	T170	G163W	163	Missense	distal	-7	no	8.583	8.713	PhosphoSitePlus	COSMIC	6.376	Up-regulation
AGC_PKC_PKCi_PRKCI_ST	Q969H0	FBXW7	P41743	PRKCI	S10	K11R	11	Missense	proximal	1	no	9.953	6.553	PhosphoSitePlus;EPSD	COSMIC	6.376	Down-regulation
AGC_PKC_PKCi_PRKCI_ST	Q969H0	FBXW7	P41743	PRKCI	S10	S7Y	7	Missense	distal	-3	no	9.953	8.465	PhosphoSitePlus;EPSD	COSMIC	6.376	Down-regulation
AGC_PKC_PKCi_PRKCI_ST	Q969H0	FBXW7	P41743	PRKCI	S10	L6F	6	Missense	distal	-4	no	9.953	9.845	PhosphoSitePlus;EPSD	COSMIC	6.376	Down-regulation
AGC_PKC_PKCi_PRKCI_ST	Q969H0	FBXW7	P41743	PRKCI	S10	S7F	7	Missense	distal	-3	no	9.953	7.542	PhosphoSitePlus;EPSD	COSMIC	6.376	Down-regulation
AGC_PKC_PKCi_PRKCI_ST	Q969H0	FBXW7	P41743	PRKCI	S10	Q3E	3	Missense	distal	-7	no	9.953	10.266	PhosphoSitePlus;EPSD	COSMIC	6.376	Up-regulation
AGC_PKC_PKCi_PRKCI_ST	Q969H0	FBXW7	P41743	PRKCI	S10	R13L	13	Missense	distal	3	no	9.953	10.592	PhosphoSitePlus;EPSD	COSMIC	6.376	Up-regulation
AGC_PKC_PKCi_PRKCI_ST	Q969H0	FBXW7	P41743	PRKCI	S18	K11R	11	Missense	distal	-7	no	9.121	8.460	EPSD;PhosphoSitePlus	COSMIC	6.376	Down-regulation
AGC_PKC_PKCi_PRKCI_ST	Q969H0	FBXW7	P41743	PRKCI	S18	R13L	13	Missense	distal	-5	no	9.121	5.806	EPSD;PhosphoSitePlus	COSMIC	6.376	Loss
AGC_PKC_PKCi_PRKCI_ST	Q969H0	FBXW7	P41743	PRKCI	S372	H379Y	379	Missense	distal	7	no	8.204	8.183	EPSD	COSMIC	6.376	Down-regulation
AGC_PKC_PKCi_PRKCI_ST	Q969H0	FBXW7	P41743	PRKCI	S372	H379P	379	Missense	distal	7	no	8.204	8.153	EPSD	COSMIC	6.376	Down-regulation
AGC_PKC_PKCi_PRKCI_ST	Q969H0	FBXW7	P41743	PRKCI	S372	R367P	367	Missense	distal	-5	no	8.204	4.526	EPSD	COSMIC	6.376	Loss
AGC_PKC_PKCi_PRKCI_ST	Q969H0	FBXW7	P41743	PRKCI	S372	V375M	375	Missense	distal	3	no	8.204	8.029	EPSD	COSMIC	6.376	Down-regulation
AGC_PKC_PKCi_PRKCI_ST	Q969H0	FBXW7	P41743	PRKCI	S372	H379R	379	Missense	distal	7	no	8.204	8.305	EPSD	COSMIC	6.376	Up-regulation
AGC_PKC_PKCi_PRKCI_ST	Q969H0	FBXW7	P41743	PRKCI	S372	K371T	371	Missense	proximal	-1	no	8.204	8.155	EPSD	COSMIC	6.376	Down-regulation
AGC_PKC_PKCi_PRKCI_ST	Q969H0	FBXW7	P41743	PRKCI	S372	G378E	378	Missense	distal	6	no	8.204	8.362	EPSD	COSMIC	6.376	Up-regulation
AGC_PKC_PKCi_PRKCI_ST	Q969H0	FBXW7	P41743	PRKCI	S372	P373L	373	Missense	proximal	1	no	8.204	7.489	EPSD	COSMIC	6.376	Down-regulation
AGC_PKC_PKCi_PRKCI_ST	Q969H0	FBXW7	P41743	PRKCI	S372	E369G	369	Missense	distal	-3	no	8.204	7.816	EPSD	COSMIC	6.376	Down-regulation
AGC_PKC_PKCi_PRKCI_ST	Q969H0	FBXW7	P41743	PRKCI	S372	R366S	366	Missense	distal	-6	no	8.204	8.390	EPSD	COSMIC	6.376	Up-regulation
AGC_PKC_PKCi_PRKCI_ST	Q969H0	FBXW7	P41743	PRKCI	S372	R366T	366	Missense	distal	-6	no	8.204	8.889	EPSD	COSMIC	6.376	Up-regulation
AGC_PKC_PKCi_PRKCI_ST	Q969H0	FBXW7	P41743	PRKCI	S372	L376S	376	Missense	distal	4	no	8.204	7.950	EPSD	COSMIC	6.376	Down-regulation
AGC_PKC_PKCi_PRKCI_ST	Q969H0	FBXW7	P41743	PRKCI	S372	R366M	366	Missense	distal	-6	no	8.204	8.856	EPSD	COSMIC	6.376	Up-regulation
AGC_PKC_PKCi_PRKCI_ST	Q969H0	FBXW7	P41743	PRKCI	T680	A685E	685	Missense	distal	5	no	7.320	7.408	EPSD	COSMIC	6.376	Up-regulation
AGC_PKC_PKCi_PRKCI_ST	Q969H0	FBXW7	P41743	PRKCI	T680	A685V	685	Missense	distal	5	no	7.320	7.048	EPSD	COSMIC	6.376	Down-regulation
AGC_PKC_PKCi_PRKCI_ST	Q969H0	FBXW7	P41743	PRKCI	T680	G687V	687	Missense	distal	7	no	7.320	7.252	EPSD	COSMIC	6.376	Down-regulation
AGC_PKC_PKCi_PRKCI_ST	Q969H0	FBXW7	P41743	PRKCI	T680	W673S	673	Missense	distal	-7	no	7.320	6.339	EPSD	COSMIC	6.376	Loss
AGC_PKC_PKCi_PRKCI_ST	Q969H0	FBXW7	P41743	PRKCI	T680	V686D	686	Missense	distal	6	no	7.320	7.389	EPSD	COSMIC	6.376	Up-regulation
AGC_PKC_PKCi_PRKCI_ST	Q969H0	FBXW7	P41743	PRKCI	T680	T680A	680	Missense	central	0	yes	7.320	0.000	EPSD	COSMIC	6.376	Loss
AGC_PKC_PKCi_PRKCI_ST	Q969H0	FBXW7	P41743	PRKCI	T680	V683M	683	Missense	distal	3	no	7.320	7.145	EPSD	COSMIC	6.376	Down-regulation
AGC_PKC_PKCi_PRKCI_ST	Q8TEW0	PARD3	P41743	PRKCI	T176	G178R	178	Missense	proximal	2	no	5.423	7.366	EPSD	COSMIC	6.376	Gain
AGC_PKC_PKCi_PRKCI_ST	Q8TEW0	PARD3	P41743	PRKCI	S187	C191W	191	Missense	distal	4	no	9.421	9.322	EPSD	COSMIC	6.376	Down-regulation
AGC_PKC_PKCi_PRKCI_ST	Q8TEW0	PARD3	P41743	PRKCI	S187	C191F	191	Missense	distal	4	no	9.421	8.814	EPSD	COSMIC	6.376	Down-regulation
AGC_PKC_PKCi_PRKCI_ST	Q8TEW0	PARD3	P41743	PRKCI	S220	N217K	217	Missense	distal	-3	no	5.592	6.401	EPSD	COSMIC	6.376	Gain
AGC_PKC_PKCi_PRKCI_ST	Q8TEW0	PARD3	P41743	PRKCI	T298	R305C	305	Missense	distal	7	no	8.325	8.075	EPSD	COSMIC	6.376	Down-regulation
AGC_PKC_PKCi_PRKCI_ST	Q8TEW0	PARD3	P41743	PRKCI	T298	R305H	305	Missense	distal	7	no	8.325	8.224	EPSD	COSMIC	6.376	Down-regulation
AGC_PKC_PKCi_PRKCI_ST	Q8TEW0	PARD3	P41743	PRKCI	T298	G300R	300	Missense	proximal	2	no	8.325	10.268	EPSD	COSMIC	6.376	Up-regulation
AGC_PKC_PKCi_PRKCI_ST	Q8TEW0	PARD3	P41743	PRKCI	T298	T298P	298	Missense	central	0	yes	8.325	0.000	EPSD	COSMIC	6.376	Loss
AGC_PKC_PKCi_PRKCI_ST	Q8TEW0	PARD3	P41743	PRKCI	T298	T298I	298	Missense	central	0	yes	8.325	0.000	EPSD	COSMIC	6.376	Loss
AGC_PKC_PKCi_PRKCI_ST	Q8TEW0	PARD3	P41743	PRKCI	T298	R294Q	294	Missense	distal	-4	no	8.325	8.245	EPSD	COSMIC;GDSC;CCLE	6.376	Down-regulation
AGC_PKC_PKCi_PRKCI_ST	Q8TEW0	PARD3	P41743	PRKCI	S386	S393I	393	Missense	distal	7	no	8.859	8.694	EPSD	COSMIC	6.376	Down-regulation
AGC_PKC_PKCi_PRKCI_ST	Q8TEW0	PARD3	P41743	PRKCI	T453	L460I	460	Missense	distal	7	no	9.219	9.205	EPSD	COSMIC	6.376	Down-regulation
AGC_PKC_PKCi_PRKCI_ST	Q8TEW0	PARD3	P41743	PRKCI	T453	V447L	447	Missense	distal	-6	no	9.219	9.391	EPSD	COSMIC	6.376	Up-regulation
AGC_PKC_PKCi_PRKCI_ST	Q8TEW0	PARD3	P41743	PRKCI	T453	R459W	459	Missense	distal	6	no	9.219	8.787	EPSD	COSMIC	6.376	Down-regulation
AGC_PKC_PKCi_PRKCI_ST	Q8TEW0	PARD3	P41743	PRKCI	T453	K455N	455	Missense	proximal	2	no	9.219	8.872	EPSD	COSMIC	6.376	Down-regulation
AGC_PKC_PKCi_PRKCI_ST	Q8TEW0	PARD3	P41743	PRKCI	T453	K455I	455	Missense	proximal	2	no	9.219	7.479	EPSD	COSMIC	6.376	Down-regulation
AGC_PKC_PKCi_PRKCI_ST	Q8TEW0	PARD3	P41743	PRKCI	T453	G457R	457	Missense	distal	4	no	9.219	8.563	EPSD	COSMIC	6.376	Down-regulation
AGC_PKC_PKCi_PRKCI_ST	Q8TEW0	PARD3	P41743	PRKCI	T468	G472V	472	Missense	distal	4	no	7.257	7.358	EPSD	COSMIC	6.376	Up-regulation
AGC_PKC_PKCi_PRKCI_ST	Q8TEW0	PARD3	P41743	PRKCI	S523	G521D	521	Missense	proximal	-2	no	7.727	7.715	EPSD	COSMIC	6.376	Down-regulation
AGC_PKC_PKCi_PRKCI_ST	Q8TEW0	PARD3	P41743	PRKCI	S529	S533N	533	Missense	distal	4	no	7.752	8.008	EPSD	COSMIC	6.376	Up-regulation
AGC_PKC_PKCi_PRKCI_ST	Q8TEW0	PARD3	P41743	PRKCI	T668	G670S	670	Missense	proximal	2	no	8.256	8.549	EPSD	COSMIC	6.376	Up-regulation
AGC_PKC_PKCi_PRKCI_ST	Q8TEW0	PARD3	P41743	PRKCI	S730	L735I	735	Missense	distal	5	no	6.460	6.293	EPSD	COSMIC	6.376	Loss
AGC_PKC_PKCi_PRKCI_ST	Q8TEW0	PARD3	P41743	PRKCI	S730	A734V	734	Missense	distal	4	no	6.460	6.931	EPSD	COSMIC	6.376	Up-regulation
AGC_PKC_PKCi_PRKCI_ST	Q8TEW0	PARD3	P41743	PRKCI	S827	S829T	829	Missense	proximal	2	no	7.362	7.708	PhosphoSitePlus	COSMIC	6.376	Up-regulation
AGC_PKC_PKCi_PRKCI_ST	Q8TEW0	PARD3	P41743	PRKCI	S827	G822E	822	Missense	distal	-5	no	7.362	9.500	PhosphoSitePlus	COSMIC	6.376	Up-regulation
AGC_PKC_PKCi_PRKCI_ST	Q8TEW0	PARD3	P41743	PRKCI	S827	R832C	832	Missense	distal	5	no	7.362	6.703	PhosphoSitePlus	COSMIC	6.376	Down-regulation
AGC_PKC_PKCi_PRKCI_ST	Q8TEW0	PARD3	P41743	PRKCI	S827	M828L	828	Missense	proximal	1	no	7.362	7.084	PhosphoSitePlus	COSMIC	6.376	Down-regulation
AGC_PKC_PKCi_PRKCI_ST	Q8TEW0	PARD3	P41743	PRKCI	S827	R820C	820	Missense	distal	-7	no	7.362	8.940	PhosphoSitePlus	COSMIC	6.376	Up-regulation
AGC_PKC_PKCi_PRKCI_ST	Q8TEW0	PARD3	P41743	PRKCI	S827	T833A	833	Missense	distal	6	no	7.362	7.338	PhosphoSitePlus	COSMIC	6.376	Down-regulation
AGC_PKC_PKCi_PRKCI_ST	Q8TEW0	PARD3	P41743	PRKCI	S829	R832C	832	Missense	distal	3	no	5.674	6.733	EPSD	COSMIC	6.376	Gain
AGC_PKC_PKCi_PRKCI_ST	Q8TEW0	PARD3	P41743	PRKCI	S852	T847K	847	Missense	distal	-5	no	8.007	8.466	EPSD	COSMIC	6.376	Up-regulation
AGC_PKC_PKCi_PRKCI_ST	Q8TEW0	PARD3	P41743	PRKCI	S852	V845I	845	Missense	distal	-7	no	8.007	7.939	EPSD	COSMIC	6.376	Down-regulation
AGC_PKC_PKCi_PRKCI_ST	Q8TEW0	PARD3	P41743	PRKCI	S852	V845L	845	Missense	distal	-7	no	8.007	7.977	EPSD	COSMIC	6.376	Down-regulation
AGC_PKC_PKCi_PRKCI_ST	Q8TEW0	PARD3	P41743	PRKCI	S852	D859A	859	Missense	distal	7	no	8.007	8.089	EPSD	COSMIC	6.376	Up-regulation
AGC_PKC_PKCi_PRKCI_ST	Q8TEW0	PARD3	P41743	PRKCI	S852	D859N	859	Missense	distal	7	no	8.007	8.073	EPSD	COSMIC	6.376	Up-regulation
AGC_PKC_PKCi_PRKCI_ST	Q8TEW0	PARD3	P41743	PRKCI	S889	G883C	883	Missense	distal	-6	no	10.239	10.456	EPSD	COSMIC	6.376	Up-regulation
AGC_PKC_PKCi_PRKCI_ST	Q8TEW0	PARD3	P41743	PRKCI	S889	K885Q	885	Missense	distal	-4	no	10.239	10.294	EPSD	COSMIC	6.376	Up-regulation
AGC_PKC_PKCi_PRKCI_ST	Q8TEW0	PARD3	P41743	PRKCI	S889	Q894K	894	Missense	distal	5	no	10.239	10.336	EPSD	COSMIC	6.376	Up-regulation
AGC_PKC_PKCi_PRKCI_ST	Q8TEW0	PARD3	P41743	PRKCI	S889	S892G	892	Missense	distal	3	no	10.239	11.052	EPSD	COSMIC	6.376	Up-regulation
AGC_PKC_PKCi_PRKCI_ST	Q8TEW0	PARD3	P41743	PRKCI	S889	S887F	887	Missense	proximal	-2	no	10.239	9.806	EPSD	COSMIC	6.376	Down-regulation
AGC_PKC_PKCi_PRKCI_ST	Q8TEW0	PARD3	P41743	PRKCI	T901	G904W	904	Missense	distal	3	no	7.048	7.280	EPSD	COSMIC	6.376	Up-regulation
AGC_PKC_PKCi_PRKCI_ST	Q8TEW0	PARD3	P41743	PRKCI	T901	P907F	907	Missense	distal	6	no	7.048	7.070	EPSD	COSMIC	6.376	Up-regulation
AGC_PKC_PKCi_PRKCI_ST	Q8TEW0	PARD3	P41743	PRKCI	T901	G904V	904	Missense	distal	3	no	7.048	6.908	EPSD	COSMIC	6.376	Down-regulation
AGC_PKC_PKCi_PRKCI_ST	Q8TEW0	PARD3	P41743	PRKCI	T901	G904R	904	Missense	distal	3	no	7.048	6.323	EPSD	COSMIC;CCLE	6.376	Loss
AGC_PKC_PKCi_PRKCI_ST	Q8TEW0	PARD3	P41743	PRKCI	T901	D905A	905	Missense	distal	4	no	7.048	6.706	EPSD	COSMIC	6.376	Down-regulation
AGC_PKC_PKCi_PRKCI_ST	Q8TEW0	PARD3	P41743	PRKCI	T901	Q894K	894	Missense	distal	-7	no	7.048	7.379	EPSD	COSMIC	6.376	Up-regulation
AGC_PKC_PKCi_PRKCI_ST	Q8TEW0	PARD3	P41743	PRKCI	S924	E923Q	923	Missense	proximal	-1	no	7.329	7.368	EPSD	COSMIC	6.376	Up-regulation
AGC_PKC_PKCi_PRKCI_ST	Q8TEW0	PARD3	P41743	PRKCI	S924	D930G	930	Missense	distal	6	no	7.329	7.343	EPSD	COSMIC	6.376	Up-regulation
AGC_PKC_PKCi_PRKCI_ST	Q8TEW0	PARD3	P41743	PRKCI	S924	I929M	929	Missense	distal	5	no	7.329	7.600	EPSD	COSMIC;GDSC	6.376	Up-regulation
AGC_PKC_PKCi_PRKCI_ST	Q8TEW0	PARD3	P41743	PRKCI	S924	A928T	928	Missense	distal	4	no	7.329	7.413	EPSD	COSMIC	6.376	Up-regulation
AGC_PKC_PKCi_PRKCI_ST	Q8TEW0	PARD3	P41743	PRKCI	S955	S956F	956	Missense	proximal	1	no	5.964	10.392	EPSD	COSMIC	6.376	Gain
AGC_PKC_PKCi_PRKCI_ST	Q8TEW0	PARD3	P41743	PRKCI	T965	G959D	959	Missense	distal	-6	no	12.389	12.329	EPSD	COSMIC	6.376	Down-regulation
AGC_PKC_PKCi_PRKCI_ST	Q8TEW0	PARD3	P41743	PRKCI	T965	S964G	964	Missense	proximal	-1	no	12.389	12.176	EPSD	COSMIC	6.376	Down-regulation
AGC_PKC_PKCi_PRKCI_ST	Q8TEW0	PARD3	P41743	PRKCI	T965	S967G	967	Missense	proximal	2	no	12.389	12.096	EPSD	COSMIC	6.376	Down-regulation
AGC_PKC_PKCi_PRKCI_ST	Q8TEW0	PARD3	P41743	PRKCI	T965	S962F	962	Missense	distal	-3	no	12.389	9.978	EPSD	COSMIC	6.376	Down-regulation
AGC_PKC_PKCi_PRKCI_ST	Q8TEW0	PARD3	P41743	PRKCI	T965	E961K	961	Missense	distal	-4	no	12.389	12.317	EPSD	COSMIC	6.376	Down-regulation
AGC_PKC_PKCi_PRKCI_ST	Q8TEW0	PARD3	P41743	PRKCI	S1116	R1113C	1113	Missense	distal	-3	no	8.175	4.103	EPSD	COSMIC	6.376	Loss
AGC_PKC_PKCi_PRKCI_ST	Q8TEW0	PARD3	P41743	PRKCI	S1116	R1118Q	1118	Missense	proximal	2	no	8.175	7.527	EPSD	COSMIC	6.376	Down-regulation
AGC_PKC_PKCi_PRKCI_ST	Q8TEW0	PARD3	P41743	PRKCI	S1116	R1118W	1118	Missense	proximal	2	no	8.175	4.910	EPSD	COSMIC	6.376	Loss
AGC_PKC_PKCi_PRKCI_ST	Q8TEW0	PARD3	P41743	PRKCI	S1116	P1117L	1117	Missense	proximal	1	no	8.175	7.460	EPSD	COSMIC	6.376	Down-regulation
AGC_PKC_PKCi_PRKCI_ST	Q8TEW0	PARD3	P41743	PRKCI	S1178	R1174C	1174	Missense	distal	-4	no	11.586	11.089	EPSD	COSMIC	6.376	Down-regulation
AGC_PKC_PKCi_PRKCI_ST	Q8TEW0	PARD3	P41743	PRKCI	S1178	R1173H	1173	Missense	distal	-5	no	11.586	9.658	EPSD	COSMIC	6.376	Down-regulation
AGC_PKC_PKCi_PRKCI_ST	Q8TEW0	PARD3	P41743	PRKCI	S1178	R1175Q	1175	Missense	distal	-3	no	11.586	9.909	EPSD	COSMIC	6.376	Down-regulation
AGC_PKC_PKCi_PRKCI_ST	Q8TEW0	PARD3	P41743	PRKCI	S1178	R1174Q	1174	Missense	distal	-4	no	11.586	11.506	EPSD	COSMIC	6.376	Down-regulation
AGC_PKC_PKCi_PRKCI_ST	Q8TEW0	PARD3	P41743	PRKCI	S1178	S1178I	1178	Missense	central	0	yes	11.586	0.000	EPSD	COSMIC;GDSC;CCLE	6.376	Loss
AGC_PKC_PKCi_PRKCI_ST	Q8TEW0	PARD3	P41743	PRKCI	S1178	E1180G	1180	Missense	proximal	2	no	11.586	10.386	EPSD	COSMIC	6.376	Down-regulation
AGC_PKC_PKCi_PRKCI_ST	Q8TEW0	PARD3	P41743	PRKCI	S1261	Y1259C	1259	Missense	proximal	-2	no	8.207	7.647	EPSD	COSMIC	6.376	Down-regulation
AGC_PKC_PKCi_PRKCI_ST	Q8TEW0	PARD3	P41743	PRKCI	S1261	P1257L	1257	Missense	distal	-4	no	8.207	8.264	EPSD	COSMIC	6.376	Up-regulation
AGC_PKC_PKCi_PRKCI_ST	Q8TEW0	PARD3	P41743	PRKCI	S1261	Y1262C	1262	Missense	proximal	1	no	8.207	6.798	EPSD	COSMIC	6.376	Down-regulation
AGC_PKC_PKCi_PRKCI_ST	Q8TEW0	PARD3	P41743	PRKCI	S1261	E1255K	1255	Missense	distal	-6	no	8.207	7.862	EPSD	COSMIC	6.376	Down-regulation
AGC_PKC_PKCi_PRKCI_ST	P78545	ELF3	P41743	PRKCI	S68	V72F	72	Missense	distal	4	no	9.480	8.999	PhosphoSitePlus	COSMIC	6.376	Down-regulation
AGC_PKC_PKCi_PRKCI_ST	P78545	ELF3	P41743	PRKCI	S68	P64T	64	Missense	distal	-4	no	9.480	9.637	PhosphoSitePlus	COSMIC;GDSC;CCLE	6.376	Up-regulation
AGC_PKC_PKCi_PRKCI_ST	P78545	ELF3	P41743	PRKCI	S68	W75R	75	Missense	distal	7	no	9.480	9.692	PhosphoSitePlus	COSMIC	6.376	Up-regulation
AGC_PKC_PKCi_PRKCI_ST	P78545	ELF3	P41743	PRKCI	S68	T70A	70	Missense	proximal	2	no	9.480	8.858	PhosphoSitePlus	COSMIC;GDSC	6.376	Down-regulation
AGC_PKC_PKCi_PRKCI_ST	P78545	ELF3	P41743	PRKCI	S206	S207F	207	Missense	proximal	1	no	4.378	8.807	EPSD	COSMIC	6.376	Gain
AGC_PKC_PKCi_PRKCI_ST	P78545	ELF3	P41743	PRKCI	S254	S254G	254	Missense	central	0	yes	8.404	0.000	EPSD	COSMIC	6.376	Loss
AGC_PKC_PKCi_PRKCI_ST	P78545	ELF3	P41743	PRKCI	S254	R251Q	251	Missense	distal	-3	no	8.404	6.726	EPSD	COSMIC	6.376	Down-regulation
AGC_PKC_PKCi_PRKCI_ST	P78545	ELF3	P41743	PRKCI	T325	R331P	331	Missense	distal	6	no	6.495	6.160	EPSD	COSMIC	6.376	Loss
AGC_PKC_PKCi_PRKCI_ST	P78545	ELF3	P41743	PRKCI	T325	A332P	332	Missense	distal	7	no	6.495	6.392	EPSD	COSMIC	6.376	Down-regulation
AGC_PKC_PKCi_PRKCI_ST	P78545	ELF3	P41743	PRKCI	T325	A332G	332	Missense	distal	7	no	6.495	6.431	EPSD	COSMIC	6.376	Down-regulation
AGC_PKC_PKCi_PRKCI_ST	P78545	ELF3	P41743	PRKCI	T325	S330C	330	Missense	distal	5	no	6.495	6.194	EPSD	COSMIC	6.376	Loss
AGC_PKC_PKCi_PRKCI_ST	P78545	ELF3	P41743	PRKCI	T325	M324V	324	Missense	proximal	-1	no	6.495	6.217	EPSD	COSMIC	6.376	Loss
AGC_PKC_PKCi_PRKCI_ST	P78545	ELF3	P41743	PRKCI	T325	S330N	330	Missense	distal	5	no	6.495	6.453	EPSD	COSMIC	6.376	Down-regulation
AGC_PKC_PKCi_PRKCI_ST	P78545	ELF3	P41743	PRKCI	T325	M324L	324	Missense	proximal	-1	no	6.495	6.387	EPSD	COSMIC	6.376	Down-regulation
AGC_PKC_PKCi_PRKCI_ST	Q16236	NFE2L2	P41743	PRKCI	S215	M212T	212	Missense	distal	-3	no	6.785	7.606	EPSD	COSMIC	6.376	Up-regulation
AGC_PKC_PKCi_PRKCI_ST	Q16236	NFE2L2	P41743	PRKCI	S215	T211I	211	Missense	distal	-4	no	6.785	6.624	EPSD	COSMIC	6.376	Down-regulation
AGC_PKC_PKCi_PRKCI_ST	Q16236	NFE2L2	P41743	PRKCI	S215	M212L	212	Missense	distal	-3	no	6.785	5.962	EPSD	COSMIC	6.376	Loss
AGC_PKC_PKCi_PRKCI_ST	Q16236	NFE2L2	P41743	PRKCI	S215	E222Q	222	Missense	distal	7	no	6.785	6.770	EPSD	COSMIC	6.376	Down-regulation
AGC_PKC_PKCi_PRKCI_ST	Q16236	NFE2L2	P41743	PRKCI	S243	L247I	247	Missense	distal	4	no	6.464	6.572	EPSD	COSMIC	6.376	Up-regulation
AGC_PKC_PKCi_PRKCI_ST	Q16236	NFE2L2	P41743	PRKCI	S243	P244A	244	Missense	proximal	1	no	6.464	4.762	EPSD	COSMIC	6.376	Loss
AGC_PKC_PKCi_PRKCI_ST	Q16236	NFE2L2	P41743	PRKCI	S243	P244L	244	Missense	proximal	1	no	6.464	5.749	EPSD	COSMIC	6.376	Loss
AGC_PKC_PKCi_PRKCI_ST	Q16236	NFE2L2	P41743	PRKCI	S243	E238Q	238	Missense	distal	-5	no	6.464	6.928	EPSD	COSMIC	6.376	Up-regulation
AGC_PKC_PKCi_PRKCI_ST	Q16236	NFE2L2	P41743	PRKCI	S243	L247F	247	Missense	distal	4	no	6.464	6.173	EPSD	COSMIC	6.376	Loss
AGC_PKC_PKCi_PRKCI_ST	Q16236	NFE2L2	P41743	PRKCI	S243	S243F	243	Missense	central	0	yes	6.464	0.000	EPSD	COSMIC	6.376	Loss
AGC_PKC_PKCi_PRKCI_ST	Q16236	NFE2L2	P41743	PRKCI	S301	A303V	303	Missense	proximal	2	no	6.676	5.629	EPSD	COSMIC	6.376	Loss
AGC_PKC_PKCi_PRKCI_ST	Q16236	NFE2L2	P41743	PRKCI	S301	S298N	298	Missense	distal	-3	no	6.676	5.506	EPSD	COSMIC	6.376	Loss
AGC_PKC_PKCi_PRKCI_ST	Q16236	NFE2L2	P41743	PRKCI	S301	P300H	300	Missense	proximal	-1	no	6.676	6.725	EPSD	COSMIC	6.376	Up-regulation
AGC_PKC_PKCi_PRKCI_ST	Q16236	NFE2L2	P41743	PRKCI	S356	S351R	351	Missense	distal	-5	no	4.369	6.858	EPSD	COSMIC	6.376	Gain
AGC_PKC_PKCi_PRKCI_ST	Q16236	NFE2L2	P41743	PRKCI	S433	T439P	439	Missense	distal	6	no	9.815	9.682	EPSD	COSMIC	6.376	Down-regulation
AGC_PKC_PKCi_PRKCI_ST	Q16236	NFE2L2	P41743	PRKCI	S433	G435V	435	Missense	proximal	2	no	9.815	8.786	EPSD	COSMIC	6.376	Down-regulation
AGC_PKC_PKCi_PRKCI_ST	Q16236	NFE2L2	P41743	PRKCI	S433	E427D	427	Missense	distal	-6	no	9.815	9.951	EPSD	COSMIC	6.376	Up-regulation
AGC_PKC_PKCi_PRKCI_ST	Q16236	NFE2L2	P41743	PRKCI	S433	E427K	427	Missense	distal	-6	no	9.815	9.471	EPSD	COSMIC	6.376	Down-regulation
AGC_PKC_PKCi_PRKCI_ST	Q16236	NFE2L2	P41743	PRKCI	S433	R437S	437	Missense	distal	4	no	9.815	10.126	EPSD	COSMIC	6.376	Up-regulation
AGC_PKC_PKCi_PRKCI_ST	Q16236	NFE2L2	P41743	PRKCI	S549	N546H	546	Missense	distal	-3	no	6.498	6.888	EPSD	COSMIC	6.376	Up-regulation
AGC_PKC_PKCi_PRKCI_ST	Q16236	NFE2L2	P41743	PRKCI	S549	K543R	543	Missense	distal	-6	no	6.498	5.855	EPSD	COSMIC	6.376	Loss
AGC_PKC_PKCi_PRKCI_ST	Q16236	NFE2L2	P41743	PRKCI	S549	H551Y	551	Missense	proximal	2	no	6.498	5.161	EPSD	COSMIC	6.376	Loss
AGC_PKC_PKCi_PRKCI_ST	Q16236	NFE2L2	P41743	PRKCI	S577	E571K	571	Missense	distal	-6	no	6.486	6.141	EPSD	COSMIC	6.376	Loss
AGC_PKC_PKCi_PRKCI_ST	Q16236	NFE2L2	P41743	PRKCI	S577	E580K	580	Missense	distal	3	no	6.486	6.400	EPSD	COSMIC	6.376	Down-regulation
AGC_PKC_PKCi_PRKCI_ST	Q16236	NFE2L2	P41743	PRKCI	S577	S577F	577	Missense	central	0	yes	6.486	0.000	EPSD	COSMIC	6.376	Loss
AGC_PKC_PKCi_PRKCI_ST	Q16236	NFE2L2	P41743	PRKCI	S577	Y581N	581	Missense	distal	4	no	6.486	6.495	EPSD	COSMIC	6.376	Up-regulation
AGC_PKC_PKCi_PRKCI_ST	Q9NPB6	PARD6A	P41743	PRKCI	S11	E17V	17	Missense	distal	6	no	7.305	7.063	EPSD	COSMIC;GDSC;CCLE	6.376	Down-regulation
AGC_PKC_PKCi_PRKCI_ST	Q9NPB6	PARD6A	P41743	PRKCI	S11	P4S	4	Missense	distal	-7	no	7.305	6.741	EPSD	COSMIC	6.376	Down-regulation
AGC_PKC_PKCi_PRKCI_ST	Q9NPB6	PARD6A	P41743	PRKCI	S109	R113C	113	Missense	distal	4	no	5.505	6.387	EPSD	COSMIC	6.376	Gain
AGC_PKC_PKCi_PRKCI_ST	Q9NPB6	PARD6A	P41743	PRKCI	S109	R112C	112	Missense	distal	3	no	5.505	6.565	EPSD	COSMIC	6.376	Gain
AGC_PKC_PKCi_PRKCI_ST	Q9NPB6	PARD6A	P41743	PRKCI	S322	R317H	317	Missense	distal	-5	no	11.808	9.879	EPSD	COSMIC;GDSC;CCLE	6.376	Down-regulation
AGC_PKC_PKCi_PRKCI_ST	Q9NPB6	PARD6A	P41743	PRKCI	S322	E327K	327	Missense	distal	5	no	11.808	12.094	EPSD	COSMIC	6.376	Up-regulation
AGC_PKC_PKCi_PRKCI_ST	Q9NPB6	PARD6A	P41743	PRKCI	S345	R338L	338	Missense	distal	-7	no	6.626	7.773	PhosphoSitePlus	COSMIC	6.376	Up-regulation
AGC_PKC_PKCi_PRKCI_ST	Q9H8V3	ECT2	P41743	PRKCI	S24	S24F	24	Missense	central	0	yes	6.713	0.000	EPSD	COSMIC	6.376	Loss
AGC_PKC_PKCi_PRKCI_ST	Q9H8V3	ECT2	P41743	PRKCI	S24	S30F	30	Missense	distal	6	no	6.713	6.586	EPSD	COSMIC	6.376	Down-regulation
AGC_PKC_PKCi_PRKCI_ST	Q9H8V3	ECT2	P41743	PRKCI	S24	I21S	21	Missense	distal	-3	no	6.713	9.167	EPSD	COSMIC;CCLE	6.376	Up-regulation
AGC_PKC_PKCi_PRKCI_ST	Q9H8V3	ECT2	P41743	PRKCI	S112	F107S	107	Missense	distal	-5	no	5.334	6.873	EPSD	COSMIC	6.376	Gain
AGC_PKC_PKCi_PRKCI_ST	Q9H8V3	ECT2	P41743	PRKCI	T359	E361G	361	Missense	proximal	2	no	8.314	7.114	PhosphoSitePlus	COSMIC	6.376	Down-regulation
AGC_PKC_PKCi_PRKCI_ST	Q9H8V3	ECT2	P41743	PRKCI	T359	T359N	359	Missense	central	0	yes	8.314	0.000	PhosphoSitePlus	COSMIC;CCLE	6.376	Loss
AGC_PKC_PKCi_PRKCI_ST	Q9H8V3	ECT2	P41743	PRKCI	T359	K363E	363	Missense	distal	4	no	8.314	8.194	PhosphoSitePlus	COSMIC	6.376	Down-regulation
AGC_PKC_PKCi_PRKCI_ST	Q9H8V3	ECT2	P41743	PRKCI	T359	Y352F	352	Missense	distal	-7	no	8.314	8.385	PhosphoSitePlus	COSMIC	6.376	Up-regulation
AGC_PKC_PKCi_PRKCI_ST	Q9H8V3	ECT2	P41743	PRKCI	T359	T359A	359	Missense	central	0	yes	8.314	0.000	PhosphoSitePlus	COSMIC	6.376	Loss
AGC_PKC_PKCi_PRKCI_ST	Q9H8V3	ECT2	P41743	PRKCI	S443	S439F	439	Missense	distal	-4	no	8.358	7.978	EPSD	COSMIC	6.376	Down-regulation
AGC_PKC_PKCi_PRKCI_ST	Q9H8V3	ECT2	P41743	PRKCI	S443	T437S	437	Missense	distal	-6	no	8.358	7.859	EPSD	COSMIC	6.376	Down-regulation
AGC_PKC_PKCi_PRKCI_ST	Q9H8V3	ECT2	P41743	PRKCI	S448	A452T	452	Missense	distal	4	no	6.742	6.826	EPSD	COSMIC	6.376	Up-regulation
AGC_PKC_PKCi_PRKCI_ST	Q9H8V3	ECT2	P41743	PRKCI	S811	K817E	817	Missense	distal	6	no	10.724	10.688	EPSD	COSMIC	6.376	Down-regulation
AGC_PKC_PKCi_PRKCI_ST	Q9H8V3	ECT2	P41743	PRKCI	S844	A850T	850	Missense	distal	6	no	10.663	10.687	EPSD	COSMIC	6.376	Up-regulation
AGC_PKC_PKCi_PRKCI_ST	Q9H8V3	ECT2	P41743	PRKCI	S844	P847L	847	Missense	distal	3	no	10.663	10.865	EPSD	COSMIC	6.376	Up-regulation
AGC_PKC_PKCi_PRKCI_ST	Q9H8V3	ECT2	P41743	PRKCI	S844	K848E	848	Missense	distal	4	no	10.663	10.543	EPSD	COSMIC	6.376	Down-regulation
AGC_PKC_PKCi_PRKCI_ST	Q9H8V3	ECT2	P41743	PRKCI	T905	S909F	909	Missense	distal	4	no	7.278	7.243	EPSD	COSMIC	6.376	Down-regulation
AGC_PKC_PKCi_PRKCI_ST	Q9H8V3	ECT2	P41743	PRKCI	T905	R908S	908	Missense	distal	3	no	7.278	7.190	EPSD	COSMIC	6.376	Down-regulation
AGC_PKC_PKCi_PRKCI_ST	Q9H8V3	ECT2	P41743	PRKCI	T905	E900Q	900	Missense	distal	-5	no	7.278	7.743	EPSD	COSMIC	6.376	Up-regulation
AGC_PKC_PKCi_PRKCI_ST	Q9H8V3	ECT2	P41743	PRKCI	T905	H912Y	912	Missense	distal	7	no	7.278	7.258	EPSD	COSMIC	6.376	Down-regulation
AGC_PKC_PKCi_PRKCI_ST	Q9H8V3	ECT2	P41743	PRKCI	T911	S909F	909	Missense	proximal	-2	no	7.022	6.590	EPSD	COSMIC	6.376	Down-regulation
AGC_PKC_PKCi_PRKCI_ST	Q9H8V3	ECT2	P41743	PRKCI	T911	R908S	908	Missense	distal	-3	no	7.022	5.966	EPSD	COSMIC	6.376	Loss
AGC_PKC_PKCi_PRKCI_ST	Q9H8V3	ECT2	P41743	PRKCI	T911	H912Y	912	Missense	proximal	1	no	7.022	6.379	EPSD	COSMIC	6.376	Down-regulation
TK_Syk_ZAP70_Y	O43561	LAT	P43403	ZAP70	Y110	G103A	103	Missense	distal	-7	no	3.340	5.457	EPSD	COSMIC	5.220	Gain
TK_Syk_ZAP70_Y	O43561	LAT	P43403	ZAP70	Y156	L162P	162	Missense	distal	6	no	7.103	6.964	EPSD	COSMIC	5.220	Down-regulation
TK_Syk_ZAP70_Y	O43561	LAT	P43403	ZAP70	Y161	L162P	162	Missense	proximal	1	no	7.882	6.275	EPSD	COSMIC	5.220	Down-regulation
TK_Syk_ZAP70_Y	O43561	LAT	P43403	ZAP70	Y161	P166S	166	Missense	distal	5	no	7.882	7.811	EPSD	COSMIC	5.220	Down-regulation
TK_Syk_ZAP70_Y	O43561	LAT	P43403	ZAP70	Y161	P166R	166	Missense	distal	5	no	7.882	7.433	EPSD	COSMIC	5.220	Down-regulation
TK_Syk_ZAP70_Y	O43561	LAT	P43403	ZAP70	Y220	R218W	218	Missense	proximal	-2	no	9.882	9.526	EPSD	COSMIC	5.220	Down-regulation
TK_Syk_ZAP70_Y	P29353	SHC1	P43403	ZAP70	Y315	F312S	312	Missense	distal	-3	no	4.688	6.348	EPSD	COSMIC	5.220	Gain
TK_Syk_ZAP70_Y	P29353	SHC1	P43403	ZAP70	Y349	E343K	343	Missense	distal	-6	no	11.718	10.483	EPSD	COSMIC	5.220	Down-regulation
TK_Syk_ZAP70_Y	P29353	SHC1	P43403	ZAP70	Y349	N351Y	351	Missense	proximal	2	no	11.718	10.899	EPSD	COSMIC	5.220	Down-regulation
TK_Syk_ZAP70_Y	P29353	SHC1	P43403	ZAP70	Y349	P354L	354	Missense	distal	5	no	11.718	11.140	EPSD	COSMIC	5.220	Down-regulation
TK_Syk_ZAP70_Y	P29353	SHC1	P43403	ZAP70	Y349	E343D	343	Missense	distal	-6	no	11.718	11.376	EPSD	COSMIC	5.220	Down-regulation
TK_Syk_ZAP70_Y	P29353	SHC1	P43403	ZAP70	Y350	E343K	343	Missense	distal	-7	no	9.502	7.788	EPSD	COSMIC	5.220	Down-regulation
TK_Syk_ZAP70_Y	P29353	SHC1	P43403	ZAP70	Y350	E357D	357	Missense	distal	7	no	9.502	9.525	EPSD	COSMIC;GDSC	5.220	Up-regulation
TK_Syk_ZAP70_Y	P29353	SHC1	P43403	ZAP70	Y350	N351Y	351	Missense	proximal	1	no	9.502	9.852	EPSD	COSMIC	5.220	Up-regulation
TK_Syk_ZAP70_Y	P29353	SHC1	P43403	ZAP70	Y350	P354L	354	Missense	distal	4	no	9.502	9.199	EPSD	COSMIC	5.220	Down-regulation
TK_Syk_ZAP70_Y	P29353	SHC1	P43403	ZAP70	Y350	E343D	343	Missense	distal	-7	no	9.502	8.958	EPSD	COSMIC	5.220	Down-regulation
TK_Syk_ZAP70_Y	P29353	SHC1	P43403	ZAP70	Y427	V430I	430	Missense	distal	3	no	9.231	8.442	EPSD	COSMIC	5.220	Down-regulation
TK_Syk_ZAP70_Y	P29353	SHC1	P43403	ZAP70	Y427	S426C	426	Missense	proximal	-1	no	9.231	9.116	EPSD	COSMIC	5.220	Down-regulation
TK_Syk_ZAP70_Y	P29353	SHC1	P43403	ZAP70	Y427	S426P	426	Missense	proximal	-1	no	9.231	9.259	EPSD	COSMIC	5.220	Up-regulation
TK_Syk_ZAP70_Y	Q9UQC2	GAB2	P43403	ZAP70	Y194	E191D	191	Missense	distal	-3	no	6.412	6.104	EPSD	COSMIC	5.220	Down-regulation
TK_Syk_ZAP70_Y	Q9UQC2	GAB2	P43403	ZAP70	Y194	H196Y	196	Missense	proximal	2	no	6.412	6.452	EPSD	COSMIC	5.220	Up-regulation
TK_Syk_ZAP70_Y	Q9UQC2	GAB2	P43403	ZAP70	Y266	T259M	259	Missense	distal	-7	no	9.840	10.147	EPSD	COSMIC	5.220	Up-regulation
TK_Syk_ZAP70_Y	Q9UQC2	GAB2	P43403	ZAP70	Y266	P269S	269	Missense	distal	3	no	9.840	8.943	EPSD	COSMIC	5.220	Down-regulation
TK_Syk_ZAP70_Y	Q9UQC2	GAB2	P43403	ZAP70	Y293	D288N	288	Missense	distal	-5	no	7.692	7.697	EPSD	COSMIC	5.220	Up-regulation
TK_Syk_ZAP70_Y	Q9UQC2	GAB2	P43403	ZAP70	Y293	T297M	297	Missense	distal	4	no	7.692	7.890	EPSD	COSMIC;GDSC	5.220	Up-regulation
TK_Syk_ZAP70_Y	Q9UQC2	GAB2	P43403	ZAP70	Y293	T287I	287	Missense	distal	-6	no	7.692	7.480	EPSD	COSMIC	5.220	Down-regulation
TK_Syk_ZAP70_Y	Q9UQC2	GAB2	P43403	ZAP70	Y324	P317L	317	Missense	distal	-7	no	6.453	5.075	EPSD	COSMIC	5.220	Loss
TK_Syk_ZAP70_Y	Q9UQC2	GAB2	P43403	ZAP70	Y324	A318T	318	Missense	distal	-6	no	6.453	5.876	EPSD	COSMIC	5.220	Down-regulation
TK_Syk_ZAP70_Y	Q9UQC2	GAB2	P43403	ZAP70	Y324	T331N	331	Missense	distal	7	no	6.453	6.432	EPSD	COSMIC	5.220	Down-regulation
TK_Syk_ZAP70_Y	Q9UQC2	GAB2	P43403	ZAP70	Y411	S405L	405	Missense	distal	-6	no	6.326	5.823	EPSD	COSMIC	5.220	Down-regulation
TK_Syk_ZAP70_Y	Q9UQC2	GAB2	P43403	ZAP70	Y411	R414H	414	Missense	distal	3	no	6.326	4.689	EPSD	COSMIC	5.220	Loss
TK_Syk_ZAP70_Y	Q9UQC2	GAB2	P43403	ZAP70	Y411	G416R	416	Missense	distal	5	no	6.326	6.707	EPSD	COSMIC	5.220	Up-regulation
TK_Syk_ZAP70_Y	Q9UQC2	GAB2	P43403	ZAP70	Y411	E417Q	417	Missense	distal	6	no	6.326	6.092	EPSD	COSMIC;GDSC;CCLE	5.220	Down-regulation
TK_Syk_ZAP70_Y	Q9UQC2	GAB2	P43403	ZAP70	Y452	P454L	454	Missense	proximal	2	no	7.321	6.306	EPSD	COSMIC	5.220	Down-regulation
TK_Syk_ZAP70_Y	Q9UQC2	GAB2	P43403	ZAP70	Y452	S459F	459	Missense	distal	7	no	7.321	7.419	EPSD	COSMIC	5.220	Up-regulation
TK_Syk_ZAP70_Y	Q9UQC2	GAB2	P43403	ZAP70	Y452	S448Y	448	Missense	distal	-4	no	7.321	7.129	EPSD	COSMIC	5.220	Down-regulation
TK_Syk_ZAP70_Y	Q9UQC2	GAB2	P43403	ZAP70	Y452	P454T	454	Missense	proximal	2	no	7.321	6.899	EPSD	COSMIC	5.220	Down-regulation
TK_Syk_ZAP70_Y	Q9UQC2	GAB2	P43403	ZAP70	Y584	D579H	579	Missense	distal	-5	no	8.096	8.117	EPSD	COSMIC	5.220	Up-regulation
TK_Syk_ZAP70_Y	Q9UQC2	GAB2	P43403	ZAP70	Y584	D579N	579	Missense	distal	-5	no	8.096	8.101	EPSD	COSMIC	5.220	Up-regulation
TK_Syk_ZAP70_Y	Q9UQC2	GAB2	P43403	ZAP70	Y584	P590R	590	Missense	distal	6	no	8.096	8.091	EPSD	COSMIC	5.220	Down-regulation
TK_Syk_ZAP70_Y	Q9UQC2	GAB2	P43403	ZAP70	Y614	T609I	609	Missense	distal	-5	no	9.402	9.412	PhosphoSitePlus	COSMIC	5.220	Up-regulation
TK_Syk_ZAP70_Y	Q9UQC2	GAB2	P43403	ZAP70	Y614	Q620P	620	Missense	distal	6	no	9.402	9.321	PhosphoSitePlus	COSMIC	5.220	Down-regulation
TK_Syk_ZAP70_Y	Q9UQC2	GAB2	P43403	ZAP70	Y643	K650R	650	Missense	distal	7	no	6.824	6.815	EPSD	COSMIC	5.220	Down-regulation
TK_Syk_ZAP70_Y	Q9UQC2	GAB2	P43403	ZAP70	Y643	Q645E	645	Missense	proximal	2	no	6.824	6.880	EPSD	COSMIC	5.220	Up-regulation
TK_Syk_ZAP70_Y	P43403	ZAP70	P43403	ZAP70	Y126	R119Q	119	Missense	distal	-7	no	8.864	9.098	EPSD;PhosphoSitePlus	COSMIC	5.220	Up-regulation
TK_Syk_ZAP70_Y	P43403	ZAP70	P43403	ZAP70	Y292	R298C	298	Missense	distal	6	no	12.294	12.402	EPSD;PhosphoSitePlus	COSMIC	5.220	Up-regulation
TK_Syk_ZAP70_Y	P43403	ZAP70	P43403	ZAP70	Y292	D285N	285	Missense	distal	-7	no	12.294	11.239	EPSD;PhosphoSitePlus	COSMIC;GDSC;CCLE	5.220	Down-regulation
TK_Syk_ZAP70_Y	P43403	ZAP70	P43403	ZAP70	Y292	R298H	298	Missense	distal	6	no	12.294	12.268	EPSD;PhosphoSitePlus	COSMIC	5.220	Down-regulation
TK_Syk_ZAP70_Y	P43403	ZAP70	P43403	ZAP70	Y315	T312M	312	Missense	distal	-3	no	9.219	9.740	PhosphoSitePlus;EPSD	COSMIC	5.220	Up-regulation
TK_Syk_ZAP70_Y	P43403	ZAP70	P43403	ZAP70	Y319	T312M	312	Missense	distal	-7	no	11.898	12.205	EPSD;PhosphoSitePlus	COSMIC	5.220	Up-regulation
TK_Syk_ZAP70_Y	P43403	ZAP70	P43403	ZAP70	Y451	G448E	448	Missense	distal	-3	no	3.403	6.088	EPSD	COSMIC;GDSC;CCLE	5.220	Gain
TK_Syk_ZAP70_Y	P43403	ZAP70	P43403	ZAP70	Y492	A495V	495	Missense	distal	3	no	8.864	8.368	EPSD;PhosphoSitePlus	COSMIC	5.220	Down-regulation
TK_Syk_ZAP70_Y	P43403	ZAP70	P43403	ZAP70	Y492	D490N	490	Missense	proximal	-2	no	8.864	8.918	EPSD;PhosphoSitePlus	COSMIC	5.220	Up-regulation
TK_Syk_ZAP70_Y	P43403	ZAP70	P43403	ZAP70	Y493	A495V	495	Missense	proximal	2	no	9.310	8.667	EPSD;PhosphoSitePlus	COSMIC	5.220	Down-regulation
TK_Syk_ZAP70_Y	P43403	ZAP70	P43403	ZAP70	Y493	D490N	490	Missense	distal	-3	no	9.310	8.541	EPSD;PhosphoSitePlus	COSMIC	5.220	Down-regulation
TK_Syk_ZAP70_Y	P43403	ZAP70	P43403	ZAP70	Y493	K500R	500	Missense	distal	7	no	9.310	9.301	EPSD;PhosphoSitePlus	COSMIC	5.220	Down-regulation
TK_Syk_ZAP70_Y	P43403	ZAP70	P43403	ZAP70	Y569	E567A	567	Missense	proximal	-2	no	6.328	6.650	EPSD	COSMIC	5.220	Up-regulation
TK_Syk_ZAP70_Y	P43403	ZAP70	P43403	ZAP70	Y569	P566L	566	Missense	distal	-3	no	6.328	4.692	EPSD	COSMIC	5.220	Loss
TK_Syk_ZAP70_Y	Q13094	LCP2	P43403	ZAP70	Y113	D112N	112	Missense	proximal	-1	no	13.540	13.343	EPSD;PhosphoSitePlus	COSMIC;GDSC;CCLE	5.220	Down-regulation
TK_Syk_ZAP70_Y	Q13094	LCP2	P43403	ZAP70	Y113	D119Y	119	Missense	distal	6	no	13.540	13.418	EPSD;PhosphoSitePlus	COSMIC	5.220	Down-regulation
TK_Syk_ZAP70_Y	Q13094	LCP2	P43403	ZAP70	Y113	E109K	109	Missense	distal	-4	no	13.540	13.268	EPSD;PhosphoSitePlus	COSMIC	5.220	Down-regulation
TK_Syk_ZAP70_Y	Q13094	LCP2	P43403	ZAP70	Y113	S115I	115	Missense	proximal	2	no	13.540	13.076	EPSD;PhosphoSitePlus	COSMIC	5.220	Down-regulation
TK_Syk_ZAP70_Y	Q13094	LCP2	P43403	ZAP70	Y145	P138R	138	Missense	distal	-7	no	13.583	11.899	PhosphoSitePlus;EPSD	COSMIC;GDSC;CCLE	5.220	Down-regulation
TK_Syk_ZAP70_Y	Q13094	LCP2	P43403	ZAP70	Y145	A143T	143	Missense	proximal	-2	no	13.583	13.059	PhosphoSitePlus;EPSD	COSMIC;GDSC;CCLE	5.220	Down-regulation
TK_Syk_ZAP70_Y	Q13094	LCP2	P43403	ZAP70	Y145	A143V	143	Missense	proximal	-2	no	13.583	12.567	PhosphoSitePlus;EPSD	COSMIC	5.220	Down-regulation
TK_Syk_ZAP70_Y	Q13094	LCP2	P43403	ZAP70	Y145	P149T	149	Missense	distal	4	no	13.583	13.370	PhosphoSitePlus;EPSD	COSMIC	5.220	Down-regulation
TK_Syk_ZAP70_Y	Q13094	LCP2	P43403	ZAP70	Y145	P149L	149	Missense	distal	4	no	13.583	13.281	PhosphoSitePlus;EPSD	COSMIC	5.220	Down-regulation
TK_Syk_ZAP70_Y	Q9UJU6	DBNL	P43403	ZAP70	Y162	V161M	161	Missense	proximal	-1	no	7.278	7.690	EPSD	COSMIC	5.220	Up-regulation
TK_Syk_ZAP70_Y	Q9UJU6	DBNL	P43403	ZAP70	Y162	S160F	160	Missense	proximal	-2	no	7.278	6.598	EPSD	COSMIC	5.220	Down-regulation
TK_Syk_ZAP70_Y	Q9UJU6	DBNL	P43403	ZAP70	Y162	V168A	168	Missense	distal	6	no	7.278	7.249	EPSD	COSMIC	5.220	Down-regulation
TK_Syk_ZAP70_Y	Q9UJU6	DBNL	P43403	ZAP70	Y162	P157S	157	Missense	distal	-5	no	7.278	7.273	EPSD	COSMIC	5.220	Down-regulation
TK_Syk_ZAP70_Y	Q9UJU6	DBNL	P43403	ZAP70	Y334	E336K	336	Missense	proximal	2	no	13.193	12.925	PhosphoSitePlus;EPSD	COSMIC	5.220	Down-regulation
TK_Syk_ZAP70_Y	Q9UJU6	DBNL	P43403	ZAP70	Y334	E336Q	336	Missense	proximal	2	no	13.193	13.137	PhosphoSitePlus;EPSD	COSMIC	5.220	Down-regulation
TK_Syk_ZAP70_Y	Q9UJU6	DBNL	P43403	ZAP70	Y334	E329K	329	Missense	distal	-5	no	13.193	13.215	PhosphoSitePlus;EPSD	COSMIC	5.220	Up-regulation
TK_Syk_ZAP70_Y	Q8N1K5	THEMIS	P43403	ZAP70	Y540	E538D	538	Missense	proximal	-2	no	11.017	11.145	EPSD;PhosphoSitePlus	COSMIC	5.220	Up-regulation
TK_Syk_ZAP70_Y	Q8N1K5	THEMIS	P43403	ZAP70	Y540	E537K	537	Missense	distal	-3	no	11.017	9.084	EPSD;PhosphoSitePlus	COSMIC	5.220	Down-regulation
TK_Syk_ZAP70_Y	Q8N1K5	THEMIS	P43403	ZAP70	Y541	E538D	538	Missense	distal	-3	no	10.532	10.224	PhosphoSitePlus;EPSD	COSMIC	5.220	Down-regulation
TK_Syk_ZAP70_Y	Q8N1K5	THEMIS	P43403	ZAP70	Y541	E537K	537	Missense	distal	-4	no	10.532	10.261	PhosphoSitePlus;EPSD	COSMIC	5.220	Down-regulation
TK_Syk_ZAP70_Y	Q16539	MAPK14	P43403	ZAP70	Y35	Y35H	35	Missense	central	0	yes	5.875	0.000	EPSD	COSMIC	5.220	Loss
TK_Syk_ZAP70_Y	Q16539	MAPK14	P43403	ZAP70	Y35	G36N	36	Missense	proximal	1	no	5.875	7.039	EPSD	COSMIC	5.220	Up-regulation
TK_Syk_ZAP70_Y	Q16539	MAPK14	P43403	ZAP70	Y35	A34T	34	Missense	proximal	-1	no	5.875	5.794	EPSD	COSMIC	5.220	Down-regulation
TK_Syk_ZAP70_Y	Q16539	MAPK14	P43403	ZAP70	Y35	G33A	33	Missense	proximal	-2	no	5.875	6.793	EPSD	COSMIC	5.220	Up-regulation
TK_Syk_ZAP70_Y	Q16539	MAPK14	P43403	ZAP70	Y323	P322R	322	Missense	proximal	-1	no	11.786	11.474	PhosphoSitePlus	COSMIC;CCLE	5.220	Down-regulation
TK_Syk_ZAP70_Y	Q16539	MAPK14	P43403	ZAP70	Y323	V319L	319	Missense	distal	-4	no	11.786	11.724	PhosphoSitePlus	COSMIC	5.220	Down-regulation
TK_Syk_ZAP70_Y	P51452	DUSP3	P43403	ZAP70	Y23	P26L	26	Missense	distal	3	no	6.312	5.066	EPSD	COSMIC	5.220	Loss
TK_Syk_ZAP70_Y	P51452	DUSP3	P43403	ZAP70	Y138	R142W	142	Missense	distal	4	no	11.685	11.529	PhosphoSitePlus;EPSD	COSMIC	5.220	Down-regulation
TK_Syk_ZAP70_Y	P51452	DUSP3	P43403	ZAP70	Y138	L139V	139	Missense	proximal	1	no	11.685	11.943	PhosphoSitePlus;EPSD	COSMIC	5.220	Up-regulation
Atypical_BCR_BCR_ST	P27348	YWHAQ	P11274	BCR	S145	D143H	143	Missense	proximal	-2	no	2.028	2.002	EPSD	COSMIC	1.927	Down-regulation
Atypical_BCR_BCR_ST	P27348	YWHAQ	P11274	BCR	T205	L206V	206	Missense	proximal	1	no	2.159	2.218	EPSD	COSMIC	1.927	Up-regulation
Atypical_BCR_BCR_ST	P27348	YWHAQ	P11274	BCR	T205	D204H	204	Missense	proximal	-1	no	2.159	1.451	EPSD	COSMIC	1.927	Loss
Atypical_BCR_BCR_ST	P63104	YWHAZ	P11274	BCR	S58	R55C	55	Missense	distal	-3	no	3.211	3.300	EPSD	COSMIC	1.927	Up-regulation
Atypical_BCR_BCR_ST	P63104	YWHAZ	P11274	BCR	S156	E154G	154	Missense	proximal	-2	no	3.782	3.729	EPSD	COSMIC;GDSC;CCLE	1.927	Down-regulation
Atypical_BCR_BCR_ST	P63104	YWHAZ	P11274	BCR	T232	W228C	228	Missense	distal	-4	no	16.666	16.622	PhosphoSitePlus	COSMIC	1.927	Down-regulation
Atypical_BCR_BCR_ST	P55196	AFDN	P11274	BCR	T209	R213Q	213	Missense	distal	4	no	2.438	2.298	EPSD	COSMIC	1.927	Down-regulation
Atypical_BCR_BCR_ST	P55196	AFDN	P11274	BCR	T209	Y203D	203	Missense	distal	-6	no	2.438	2.390	EPSD	COSMIC	1.927	Down-regulation
Atypical_BCR_BCR_ST	P55196	AFDN	P11274	BCR	T209	E208K	208	Missense	proximal	-1	no	2.438	1.961	EPSD	COSMIC	1.927	Down-regulation
Atypical_BCR_BCR_ST	P55196	AFDN	P11274	BCR	T209	M206I	206	Missense	distal	-3	no	2.438	2.386	EPSD	COSMIC	1.927	Down-regulation
Atypical_BCR_BCR_ST	P55196	AFDN	P11274	BCR	S557	A563V	563	Missense	distal	6	no	2.768	2.777	EPSD	COSMIC	1.927	Up-regulation
Atypical_BCR_BCR_ST	P55196	AFDN	P11274	BCR	S557	R559K	559	Missense	proximal	2	no	2.768	2.739	EPSD	COSMIC	1.927	Down-regulation
Atypical_BCR_BCR_ST	P55196	AFDN	P11274	BCR	S557	S564C	564	Missense	distal	7	no	2.768	2.866	EPSD	COSMIC	1.927	Up-regulation
Atypical_BCR_BCR_ST	P55196	AFDN	P11274	BCR	S672	V667I	667	Missense	distal	-5	no	2.156	2.003	EPSD	COSMIC	1.927	Down-regulation
Atypical_BCR_BCR_ST	P55196	AFDN	P11274	BCR	S672	V666I	666	Missense	distal	-6	no	2.156	2.073	EPSD	COSMIC	1.927	Down-regulation
Atypical_BCR_BCR_ST	P55196	AFDN	P11274	BCR	T909	E907K	907	Missense	proximal	-2	no	14.315	14.271	PhosphoSitePlus	COSMIC	1.927	Down-regulation
Atypical_BCR_BCR_ST	P55196	AFDN	P11274	BCR	T909	R915C	915	Missense	distal	6	no	14.315	14.322	PhosphoSitePlus	COSMIC	1.927	Up-regulation
Atypical_BCR_BCR_ST	P55196	AFDN	P11274	BCR	T909	R915H	915	Missense	distal	6	no	14.315	14.330	PhosphoSitePlus	COSMIC	1.927	Up-regulation
Atypical_BCR_BCR_ST	P55196	AFDN	P11274	BCR	T909	D911N	911	Missense	proximal	2	no	14.315	14.174	PhosphoSitePlus	COSMIC	1.927	Down-regulation
Atypical_BCR_BCR_ST	P55196	AFDN	P11274	BCR	T909	N908K	908	Missense	proximal	-1	no	14.315	13.760	PhosphoSitePlus	COSMIC	1.927	Down-regulation
Atypical_BCR_BCR_ST	P55196	AFDN	P11274	BCR	T909	E912Q	912	Missense	distal	3	no	14.315	14.047	PhosphoSitePlus	COSMIC	1.927	Down-regulation
Atypical_BCR_BCR_ST	P55196	AFDN	P11274	BCR	S1236	R1241W	1241	Missense	distal	5	no	2.763	2.776	EPSD	COSMIC	1.927	Up-regulation
Atypical_BCR_BCR_ST	P55196	AFDN	P11274	BCR	S1236	R1241L	1241	Missense	distal	5	no	2.763	2.654	EPSD	COSMIC	1.927	Down-regulation
Atypical_BCR_BCR_ST	P55196	AFDN	P11274	BCR	S1238	R1241W	1241	Missense	distal	3	no	2.265	2.310	EPSD	COSMIC	1.927	Up-regulation
Atypical_BCR_BCR_ST	P55196	AFDN	P11274	BCR	S1238	P1245S	1245	Missense	distal	7	no	2.265	2.398	EPSD	COSMIC	1.927	Up-regulation
Atypical_BCR_BCR_ST	P55196	AFDN	P11274	BCR	S1238	R1241L	1241	Missense	distal	3	no	2.265	1.643	EPSD	COSMIC	1.927	Loss
Atypical_BCR_BCR_ST	P55196	AFDN	P11274	BCR	S1238	P1244S	1244	Missense	distal	6	no	2.265	2.268	EPSD	COSMIC	1.927	Up-regulation
Atypical_BCR_BCR_ST	P55196	AFDN	P11274	BCR	S1300	A1295T	1295	Missense	distal	-5	no	1.812	1.948	EPSD	COSMIC	1.927	Gain
Atypical_BCR_BCR_ST	P55196	AFDN	P11274	BCR	S1310	W1305L	1305	Missense	distal	-5	no	1.691	2.118	EPSD	COSMIC	1.927	Gain
Atypical_BCR_BCR_ST	P55196	AFDN	P11274	BCR	T1316	S1309F	1309	Missense	distal	-7	no	1.911	2.277	EPSD	COSMIC	1.927	Gain
Atypical_BCR_BCR_ST	P55196	AFDN	P11274	BCR	T1316	S1309I	1309	Missense	distal	-7	no	1.911	1.991	EPSD	COSMIC	1.927	Gain
Atypical_BCR_BCR_ST	P55196	AFDN	P11274	BCR	S1333	S1333F	1333	Missense	central	0	yes	2.358	0.000	EPSD	COSMIC	1.927	Loss
Atypical_BCR_BCR_ST	P55196	AFDN	P11274	BCR	S1333	S1326F	1326	Missense	distal	-7	no	2.358	2.724	EPSD	COSMIC	1.927	Up-regulation
Atypical_BCR_BCR_ST	P55196	AFDN	P11274	BCR	S1333	P1331L	1331	Missense	proximal	-2	no	2.358	2.306	EPSD	COSMIC	1.927	Down-regulation
Atypical_BCR_BCR_ST	P55196	AFDN	P11274	BCR	S1506	L1511V	1511	Missense	distal	5	no	1.856	1.935	EPSD	COSMIC	1.927	Gain
Atypical_BCR_BCR_ST	P55196	AFDN	P11274	BCR	S1506	S1510N	1510	Missense	distal	4	no	1.856	1.982	EPSD	COSMIC	1.927	Gain
Other_WEE_Myt1_PKMYT1_ST	P06493	CDK1	Q99640	PKMYT1	T14	V18L	18	Missense	distal	4	no	4.767	4.397	PhosphoSitePlus;EPSD	COSMIC	1.669	Down-regulation
Other_WEE_Myt1_PKMYT1_ST	P06493	CDK1	Q99640	PKMYT1	T14	E12K	12	Missense	proximal	-2	no	4.767	4.961	PhosphoSitePlus;EPSD	COSMIC	1.669	Up-regulation
Other_WEE_Myt1_PKMYT1_ST	P06493	CDK1	Q99640	PKMYT1	T14	Y15C	15	Missense	proximal	1	no	4.767	4.267	PhosphoSitePlus;EPSD	COSMIC	1.669	Down-regulation
Other_WEE_Myt1_PKMYT1_ST	P06493	CDK1	Q99640	PKMYT1	S53	S53C	53	Missense	central	0	yes	1.729	0.000	EPSD	COSMIC	1.669	Loss
Other_NEK_NEK6_NEK7_ST	Q15058	KIF14	Q8TDX7	NEK7	S56	G58D	58	Missense	proximal	2	no	8.347	8.456	PhosphoSitePlus;EPSD	COSMIC	3.120	Up-regulation
Other_NEK_NEK6_NEK7_ST	Q15058	KIF14	Q8TDX7	NEK7	T81	P84S	84	Missense	distal	3	no	3.616	3.595	EPSD	COSMIC;CCLE	3.120	Down-regulation
Other_NEK_NEK6_NEK7_ST	Q15058	KIF14	Q8TDX7	NEK7	T81	V85L	85	Missense	distal	4	no	3.616	3.862	EPSD	COSMIC	3.120	Up-regulation
Other_NEK_NEK6_NEK7_ST	Q15058	KIF14	Q8TDX7	NEK7	T81	M78I	78	Missense	distal	-3	no	3.616	3.477	EPSD	COSMIC	3.120	Down-regulation
Other_NEK_NEK6_NEK7_ST	Q15058	KIF14	Q8TDX7	NEK7	T81	P79T	79	Missense	proximal	-2	no	3.616	3.687	EPSD	COSMIC	3.120	Up-regulation
Other_NEK_NEK6_NEK7_ST	Q15058	KIF14	Q8TDX7	NEK7	T360	R364C	364	Missense	distal	4	no	3.578	3.573	EPSD	COSMIC	3.120	Down-regulation
Other_NEK_NEK6_NEK7_ST	Q15058	KIF14	Q8TDX7	NEK7	T360	P367L	367	Missense	distal	7	no	3.578	3.424	EPSD	COSMIC	3.120	Down-regulation
Other_NEK_NEK6_NEK7_ST	Q15058	KIF14	Q8TDX7	NEK7	T360	A362V	362	Missense	proximal	2	no	3.578	3.617	EPSD	COSMIC	3.120	Up-regulation
Other_NEK_NEK6_NEK7_ST	Q15058	KIF14	Q8TDX7	NEK7	T360	R364H	364	Missense	distal	4	no	3.578	3.562	EPSD	COSMIC	3.120	Down-regulation
Other_NEK_NEK6_NEK7_ST	Q15058	KIF14	Q8TDX7	NEK7	T632	S625I	625	Missense	distal	-7	no	3.875	3.398	EPSD	COSMIC	3.120	Down-regulation
Other_NEK_NEK6_NEK7_ST	Q15058	KIF14	Q8TDX7	NEK7	T632	N627T	627	Missense	distal	-5	no	3.875	3.829	EPSD	COSMIC	3.120	Down-regulation
Other_NEK_NEK6_NEK7_ST	Q15058	KIF14	Q8TDX7	NEK7	S1183	D1176N	1176	Missense	distal	-7	no	2.350	4.214	EPSD	COSMIC	3.120	Gain
Other_NEK_NEK6_NEK7_ST	Q15058	KIF14	Q8TDX7	NEK7	S1217	D1224A	1224	Missense	distal	7	no	7.414	7.140	EPSD;PhosphoSitePlus	COSMIC	3.120	Down-regulation
Other_NEK_NEK6_NEK7_ST	Q15058	KIF14	Q8TDX7	NEK7	S1217	D1224N	1224	Missense	distal	7	no	7.414	7.310	EPSD;PhosphoSitePlus	COSMIC;CCLE	3.120	Down-regulation
Other_NEK_NEK6_NEK7_ST	Q15058	KIF14	Q8TDX7	NEK7	S1219	D1224A	1224	Missense	distal	5	no	7.531	7.420	EPSD;PhosphoSitePlus	COSMIC	3.120	Down-regulation
Other_NEK_NEK6_NEK7_ST	Q15058	KIF14	Q8TDX7	NEK7	S1219	D1224N	1224	Missense	distal	5	no	7.531	7.411	EPSD;PhosphoSitePlus	COSMIC;CCLE	3.120	Down-regulation
Other_NEK_NEK6_NEK7_ST	Q15058	KIF14	Q8TDX7	NEK7	S1219	S1226T	1226	Missense	distal	7	no	7.531	7.677	EPSD;PhosphoSitePlus	COSMIC	3.120	Up-regulation
Other_NEK_NEK6_NEK7_ST	Q15058	KIF14	Q8TDX7	NEK7	S1220	S1227R	1227	Missense	distal	7	no	7.362	7.637	EPSD;PhosphoSitePlus	COSMIC	3.120	Up-regulation
Other_NEK_NEK6_NEK7_ST	Q15058	KIF14	Q8TDX7	NEK7	S1220	D1224A	1224	Missense	distal	4	no	7.362	7.245	EPSD;PhosphoSitePlus	COSMIC	3.120	Down-regulation
Other_NEK_NEK6_NEK7_ST	Q15058	KIF14	Q8TDX7	NEK7	S1220	D1224N	1224	Missense	distal	4	no	7.362	7.266	EPSD;PhosphoSitePlus	COSMIC;CCLE	3.120	Down-regulation
Other_NEK_NEK6_NEK7_ST	Q15058	KIF14	Q8TDX7	NEK7	S1220	S1226T	1226	Missense	distal	6	no	7.362	7.417	EPSD;PhosphoSitePlus	COSMIC	3.120	Up-regulation
Other_NEK_NEK6_NEK7_ST	Q15058	KIF14	Q8TDX7	NEK7	S1227	D1224A	1224	Missense	distal	-3	no	2.632	4.111	EPSD	COSMIC	3.120	Gain
Other_NEK_NEK6_NEK7_ST	Q15058	KIF14	Q8TDX7	NEK7	S1227	D1224N	1224	Missense	distal	-3	no	2.632	3.372	EPSD	COSMIC;CCLE	3.120	Gain
Other_NEK_NEK6_NEK7_ST	P54274	TERF1	Q8TDX7	NEK7	S252	S252L	252	Missense	central	0	yes	3.903	0.000	EPSD	COSMIC	3.120	Loss
Other_NEK_NEK6_NEK7_ST	P54274	TERF1	Q8TDX7	NEK7	T344	T348K	348	Missense	distal	4	no	3.631	3.733	EPSD	COSMIC	3.120	Up-regulation
Other_NEK_NEK6_NEK7_ST	P54274	TERF1	Q8TDX7	NEK7	T344	P345H	345	Missense	proximal	1	no	3.631	3.597	EPSD	COSMIC	3.120	Down-regulation
Other_NEK_NEK6_NEK7_ST	P54274	TERF1	Q8TDX7	NEK7	T344	S347R	347	Missense	distal	3	no	3.631	3.642	EPSD	COSMIC	3.120	Up-regulation
Other_NEK_NEK6_NEK7_ST	P54274	TERF1	Q8TDX7	NEK7	S404	E400G	400	Missense	distal	-4	no	3.291	3.348	EPSD	COSMIC;GDSC;CCLE	3.120	Up-regulation
Other_NEK_NEK6_NEK7_ST	P54274	TERF1	Q8TDX7	NEK7	S404	L408F	408	Missense	distal	4	no	3.291	3.046	EPSD	COSMIC	3.120	Loss
Other_NEK_NEK6_NEK7_ST	P52732	KIF11	Q8TDX7	NEK7	S36	R33Q	33	Missense	distal	-3	no	4.510	4.599	EPSD	COSMIC	3.120	Up-regulation
Other_NEK_NEK6_NEK7_ST	P52732	KIF11	Q8TDX7	NEK7	S36	E42G	42	Missense	distal	6	no	4.510	4.579	EPSD	COSMIC	3.120	Up-regulation
Other_NEK_NEK6_NEK7_ST	P52732	KIF11	Q8TDX7	NEK7	S240	F239L	239	Missense	proximal	-1	no	4.407	4.396	EPSD	COSMIC	3.120	Down-regulation
Other_NEK_NEK6_NEK7_ST	P52732	KIF11	Q8TDX7	NEK7	T294	R297M	297	Missense	distal	3	no	5.252	5.253	EPSD	COSMIC	3.120	Up-regulation
Other_NEK_NEK6_NEK7_ST	P52732	KIF11	Q8TDX7	NEK7	T463	E462K	462	Missense	proximal	-1	no	3.451	3.454	EPSD	COSMIC	3.120	Up-regulation
CMGC_DYRK_DYRK2_DYRK3_ST	Q96B36	AKT1S1	O43781	DYRK3	T32	V29L	29	Missense	distal	-3	no	1.094	2.381	EPSD	COSMIC	1.682	Gain
CMGC_DYRK_DYRK2_DYRK3_ST	Q96B36	AKT1S1	O43781	DYRK3	T73	P78A	78	Missense	distal	5	no	2.208	2.178	EPSD	COSMIC	1.682	Down-regulation
CMGC_DYRK_DYRK2_DYRK3_ST	Q96B36	AKT1S1	O43781	DYRK3	T73	A74T	74	Missense	proximal	1	no	2.208	2.199	EPSD	COSMIC	1.682	Down-regulation
CMGC_DYRK_DYRK2_DYRK3_ST	Q96B36	AKT1S1	O43781	DYRK3	T73	A79S	79	Missense	distal	6	no	2.208	2.366	EPSD	COSMIC	1.682	Up-regulation
CMGC_DYRK_DYRK2_DYRK3_ST	Q96B36	AKT1S1	O43781	DYRK3	T73	A79V	79	Missense	distal	6	no	2.208	2.146	EPSD	COSMIC	1.682	Down-regulation
CMGC_DYRK_DYRK2_DYRK3_ST	Q96B36	AKT1S1	O43781	DYRK3	T73	R76Q	76	Missense	distal	3	no	2.208	2.153	EPSD	COSMIC	1.682	Down-regulation
CMGC_DYRK_DYRK2_DYRK3_ST	Q96B36	AKT1S1	O43781	DYRK3	T73	P78S	78	Missense	distal	5	no	2.208	2.131	EPSD	COSMIC	1.682	Down-regulation
CMGC_DYRK_DYRK2_DYRK3_ST	Q96B36	AKT1S1	O43781	DYRK3	T97	S92I	92	Missense	distal	-5	no	2.413	2.430	EPSD	COSMIC	1.682	Up-regulation
CMGC_DYRK_DYRK2_DYRK3_ST	Q96B36	AKT1S1	O43781	DYRK3	T97	E104K	104	Missense	distal	7	no	2.413	2.568	EPSD	COSMIC	1.682	Up-regulation
CMGC_DYRK_DYRK2_DYRK3_ST	Q96B36	AKT1S1	O43781	DYRK3	T97	P93T	93	Missense	distal	-4	no	2.413	2.474	EPSD	COSMIC	1.682	Up-regulation
CMGC_DYRK_DYRK2_DYRK3_ST	Q96B36	AKT1S1	O43781	DYRK3	S187	A181T	181	Missense	distal	-6	no	2.735	2.726	EPSD	COSMIC	1.682	Down-regulation
CMGC_DYRK_DYRK2_DYRK3_ST	Q96B36	AKT1S1	O43781	DYRK3	S187	A181V	181	Missense	distal	-6	no	2.735	2.708	EPSD	COSMIC	1.682	Down-regulation
CMGC_DYRK_DYRK2_DYRK3_ST	Q96B36	AKT1S1	O43781	DYRK3	S187	P185H	185	Missense	proximal	-2	no	2.735	1.731	EPSD	COSMIC	1.682	Down-regulation
CMGC_DYRK_DYRK2_DYRK3_ST	Q96B36	AKT1S1	O43781	DYRK3	S187	V190L	190	Missense	distal	3	no	2.735	2.725	EPSD	COSMIC	1.682	Down-regulation
CMGC_DYRK_DYRK2_DYRK3_ST	Q96B36	AKT1S1	O43781	DYRK3	S187	Y180C	180	Missense	distal	-7	no	2.735	2.690	EPSD	COSMIC	1.682	Down-regulation
CMGC_DYRK_DYRK2_DYRK3_ST	Q96B36	AKT1S1	O43781	DYRK3	S211	D204N	204	Missense	distal	-7	no	1.785	1.767	EPSD	COSMIC	1.682	Down-regulation
CMGC_DYRK_DYRK2_DYRK3_ST	Q96B36	AKT1S1	O43781	DYRK3	S211	E205K	205	Missense	distal	-6	no	1.785	1.782	EPSD	COSMIC	1.682	Down-regulation
CMGC_DYRK_DYRK2_DYRK3_ST	Q96B36	AKT1S1	O43781	DYRK3	S211	S212L	212	Missense	proximal	1	no	1.785	1.779	EPSD	COSMIC	1.682	Down-regulation
CMGC_DYRK_DYRK2_DYRK3_ST	Q96B36	AKT1S1	O43781	DYRK3	S211	D214Y	214	Missense	distal	3	no	1.785	1.774	EPSD	COSMIC	1.682	Down-regulation
CMGC_DYRK_DYRK2_DYRK3_ST	Q96B36	AKT1S1	O43781	DYRK3	S211	P209L	209	Missense	proximal	-2	no	1.785	1.454	EPSD	COSMIC	1.682	Loss
CMGC_DYRK_DYRK2_DYRK3_ST	Q96B36	AKT1S1	O43781	DYRK3	S212	P209L	209	Missense	distal	-3	no	0.437	1.708	EPSD	COSMIC	1.682	Gain
TK_Tec_TXK_Y	P42681	TXK	P42681	TXK	Y91	L94I	94	Missense	distal	3	no	5.928	6.077	EPSD;PhosphoSitePlus	COSMIC	1.475	Up-regulation
TK_Tec_TXK_Y	P42681	TXK	P42681	TXK	Y91	I85M	85	Missense	distal	-6	no	5.928	5.949	EPSD;PhosphoSitePlus	COSMIC	1.475	Up-regulation
TK_Tec_TXK_Y	P42681	TXK	P42681	TXK	Y91	K88N	88	Missense	distal	-3	no	5.928	5.844	EPSD;PhosphoSitePlus	COSMIC;GDSC;CCLE	1.475	Down-regulation
TK_Tec_TXK_Y	P42681	TXK	P42681	TXK	Y420	D417Y	417	Missense	distal	-3	no	5.628	5.140	PhosphoSitePlus;EPSD	COSMIC	1.475	Down-regulation
TKL_STKR_STKR1_BMPR1B_ST	Q15796	SMAD2	O00238	BMPR1B	S47	K53E	53	Missense	distal	6	no	-0.987	-1.026	EPSD	COSMIC	-1.120	Down-regulation
TKL_STKR_STKR1_BMPR1B_ST	Q15796	SMAD2	O00238	BMPR1B	S47	W40G	40	Missense	distal	-7	no	-0.987	-0.955	EPSD	COSMIC	-1.120	Up-regulation
TKL_STKR_STKR1_BMPR1B_ST	Q15796	SMAD2	O00238	BMPR1B	S47	K54T	54	Missense	distal	7	no	-0.987	-1.059	EPSD	COSMIC	-1.120	Down-regulation
TKL_STKR_STKR1_BMPR1B_ST	Q15796	SMAD2	O00238	BMPR1B	S47	E42Q	42	Missense	distal	-5	no	-0.987	-0.981	EPSD	COSMIC	-1.120	Up-regulation
TKL_STKR_STKR1_BMPR1B_ST	Q15796	SMAD2	O00238	BMPR1B	S317	G314S	314	Missense	distal	-3	no	-1.119	-1.118	EPSD	COSMIC	-1.120	Up-regulation
TKL_STKR_STKR1_BMPR1B_ST	Q15796	SMAD2	O00238	BMPR1B	S317	N320K	320	Missense	distal	3	no	-1.119	-1.109	EPSD	COSMIC	-1.120	Up-regulation
TKL_STKR_STKR1_BMPR1B_ST	Q15796	SMAD2	O00238	BMPR1B	S317	R310T	310	Missense	distal	-7	no	-1.119	-1.125	EPSD	COSMIC	-1.120	Loss
TKL_STKR_STKR1_BMPR1B_ST	Q15796	SMAD2	O00238	BMPR1B	S317	C312W	312	Missense	distal	-5	no	-1.119	-1.116	EPSD	COSMIC	-1.120	Up-regulation
TKL_STKR_STKR1_BMPR1B_ST	Q15796	SMAD2	O00238	BMPR1B	S317	V319L	319	Missense	proximal	2	no	-1.119	-1.117	EPSD	COSMIC	-1.120	Up-regulation
TKL_STKR_STKR1_BMPR1B_ST	Q15796	SMAD2	O00238	BMPR1B	S317	V319A	319	Missense	proximal	2	no	-1.119	-1.120	EPSD	COSMIC	-1.120	Down-regulation
TKL_STKR_STKR1_BMPR1B_ST	Q15796	SMAD2	O00238	BMPR1B	S317	R310W	310	Missense	distal	-7	no	-1.119	-1.127	EPSD	COSMIC	-1.120	Loss
TKL_STKR_STKR1_BMPR1B_ST	Q15796	SMAD2	O00238	BMPR1B	S317	V319D	319	Missense	proximal	2	no	-1.119	-1.120	EPSD	COSMIC	-1.120	Down-regulation
TKL_STKR_STKR1_BMPR1B_ST	Q15796	SMAD2	O00238	BMPR1B	S417	M416V	416	Missense	proximal	-1	no	-1.094	-1.099	EPSD	COSMIC	-1.120	Down-regulation
TKL_STKR_STKR1_BMPR1B_ST	Q15796	SMAD2	O00238	BMPR1B	S417	M416R	416	Missense	proximal	-1	no	-1.094	-1.099	EPSD	COSMIC	-1.120	Down-regulation
TKL_STKR_STKR1_BMPR1B_ST	Q15796	SMAD2	O00238	BMPR1B	S417	R410G	410	Missense	distal	-7	no	-1.094	-1.070	EPSD	COSMIC	-1.120	Up-regulation
TKL_STKR_STKR1_BMPR1B_ST	Q15796	SMAD2	O00238	BMPR1B	S417	K420Q	420	Missense	distal	3	no	-1.094	-1.097	EPSD	COSMIC	-1.120	Down-regulation
TKL_STKR_STKR1_BMPR1B_ST	Q15796	SMAD2	O00238	BMPR1B	S417	S417N	417	Missense	central	0	yes	-1.094	0.000	EPSD	COSMIC	-1.120	Loss
TKL_STKR_STKR1_BMPR1B_ST	Q15796	SMAD2	O00238	BMPR1B	S417	T413N	413	Missense	distal	-4	no	-1.094	-1.096	EPSD	COSMIC	-1.120	Down-regulation
TKL_STKR_STKR1_BMPR1B_ST	Q15796	SMAD2	O00238	BMPR1B	S464	C463F	463	Missense	proximal	-1	no	-0.891	-0.892	EPSD;PhosphoSitePlus	COSMIC	-1.120	Down-regulation
TKL_STKR_STKR1_BMPR1B_ST	Q15796	SMAD2	O00238	BMPR1B	S464	G457R	457	Missense	distal	-7	no	-0.891	-0.916	EPSD;PhosphoSitePlus	COSMIC	-1.120	Down-regulation
TKL_STKR_STKR1_BMPR1B_ST	Q15796	SMAD2	O00238	BMPR1B	S464	S465I	465	Missense	proximal	1	no	-0.891	-0.902	EPSD;PhosphoSitePlus	COSMIC	-1.120	Down-regulation
TKL_STKR_STKR1_BMPR1B_ST	Q15796	SMAD2	O00238	BMPR1B	S464	C463Y	463	Missense	proximal	-1	no	-0.891	-0.892	EPSD;PhosphoSitePlus	COSMIC	-1.120	Down-regulation
TKL_STKR_STKR1_BMPR1B_ST	Q15796	SMAD2	O00238	BMPR1B	S464	S465N	465	Missense	proximal	1	no	-0.891	-0.902	EPSD;PhosphoSitePlus	COSMIC;GDSC;CCLE	-1.120	Down-regulation
TKL_STKR_STKR1_BMPR1B_ST	Q15796	SMAD2	O00238	BMPR1B	S464	P459H	459	Missense	distal	-5	no	-0.891	-0.895	EPSD;PhosphoSitePlus	COSMIC	-1.120	Down-regulation
TKL_STKR_STKR1_BMPR1B_ST	Q15796	SMAD2	O00238	BMPR1B	S464	S465R	465	Missense	proximal	1	no	-0.891	-0.902	EPSD;PhosphoSitePlus	COSMIC	-1.120	Down-regulation
TKL_STKR_STKR1_BMPR1B_ST	Q15796	SMAD2	O00238	BMPR1B	S464	S464L	464	Missense	central	0	yes	-0.891	0.000	EPSD;PhosphoSitePlus	COSMIC	-1.120	Loss
TKL_STKR_STKR1_BMPR1B_ST	Q15796	SMAD2	O00238	BMPR1B	S465	S465I	465	Missense	central	0	yes	-0.817	0.000	PhosphoSitePlus;EPSD	COSMIC	-1.120	Loss
TKL_STKR_STKR1_BMPR1B_ST	Q15796	SMAD2	O00238	BMPR1B	S465	S465N	465	Missense	central	0	yes	-0.817	0.000	PhosphoSitePlus;EPSD	COSMIC;GDSC;CCLE	-1.120	Loss
TKL_STKR_STKR1_BMPR1B_ST	Q15796	SMAD2	O00238	BMPR1B	S465	S465R	465	Missense	central	0	yes	-0.817	0.000	PhosphoSitePlus;EPSD	COSMIC	-1.120	Loss
TKL_STKR_STKR1_BMPR1B_ST	Q15796	SMAD2	O00238	BMPR1B	S465	S464L	464	Missense	proximal	-1	no	-0.817	-0.825	PhosphoSitePlus;EPSD	COSMIC	-1.120	Down-regulation
TKL_STKR_STKR1_BMPR1B_ST	Q15796	SMAD2	O00238	BMPR1B	S467	R462C	462	Missense	distal	-5	no	-0.834	-0.839	EPSD;PhosphoSitePlus	COSMIC;GDSC;CCLE	-1.120	Down-regulation
TKL_STKR_STKR1_BMPR1B_ST	Q15796	SMAD2	O00238	BMPR1B	S467	S465I	465	Missense	proximal	-2	no	-0.834	-0.829	EPSD;PhosphoSitePlus	COSMIC	-1.120	Up-regulation
TKL_STKR_STKR1_BMPR1B_ST	Q15796	SMAD2	O00238	BMPR1B	S467	S465N	465	Missense	proximal	-2	no	-0.834	-0.830	EPSD;PhosphoSitePlus	COSMIC;GDSC;CCLE	-1.120	Up-regulation
TKL_STKR_STKR1_BMPR1B_ST	Q15796	SMAD2	O00238	BMPR1B	S467	S465R	465	Missense	proximal	-2	no	-0.834	-0.831	EPSD;PhosphoSitePlus	COSMIC	-1.120	Up-regulation
TKL_STKR_STKR1_BMPR1B_ST	Q15796	SMAD2	O00238	BMPR1B	S467	S464L	464	Missense	distal	-3	no	-0.834	-0.832	EPSD;PhosphoSitePlus	COSMIC	-1.120	Up-regulation
TKL_STKR_STKR1_BMPR1B_ST	Q15797	SMAD1	O00238	BMPR1B	T10	K15R	15	Missense	distal	5	no	-1.075	-1.144	EPSD	COSMIC	-1.120	Loss
TKL_STKR_STKR1_BMPR1B_ST	Q15797	SMAD1	O00238	BMPR1B	T10	K15N	15	Missense	distal	5	no	-1.075	-1.143	EPSD	COSMIC	-1.120	Loss
TKL_STKR_STKR1_BMPR1B_ST	Q15797	SMAD1	O00238	BMPR1B	S11	K15R	15	Missense	distal	4	no	-1.096	-1.165	EPSD	COSMIC	-1.120	Loss
TKL_STKR_STKR1_BMPR1B_ST	Q15797	SMAD1	O00238	BMPR1B	S11	K15N	15	Missense	distal	4	no	-1.096	-1.165	EPSD	COSMIC	-1.120	Loss
TK_Jak_TYK2_Y	P63244	RACK1	P29597	TYK2	Y194	H188D	188	Missense	distal	-6	no	44.091	42.019	PhosphoSitePlus	COSMIC	21.015	Down-regulation
TK_Jak_TYK2_Y	P63244	RACK1	P29597	TYK2	Y194	L195M	195	Missense	proximal	1	no	44.091	44.050	PhosphoSitePlus	COSMIC	21.015	Down-regulation
TK_Jak_TYK2_Y	P29597	TYK2	P29597	TYK2	Y1054	Y1054H	1054	Missense	central	0	yes	39.574	0.000	EPSD;PhosphoSitePlus	COSMIC;GDSC;CCLE	21.015	Loss
TK_Jak_TYK2_Y	P29597	TYK2	P29597	TYK2	Y1054	E1050G	1050	Missense	distal	-4	no	39.574	41.901	EPSD;PhosphoSitePlus	COSMIC	21.015	Up-regulation
TK_Jak_TYK2_Y	P29597	TYK2	P29597	TYK2	Y1055	D1062G	1062	Missense	distal	7	no	39.028	36.593	EPSD;PhosphoSitePlus	COSMIC	21.015	Down-regulation
TK_Jak_TYK2_Y	P29597	TYK2	P29597	TYK2	Y1055	Y1054H	1054	Missense	proximal	-1	no	39.028	36.462	EPSD;PhosphoSitePlus	COSMIC;GDSC;CCLE	21.015	Down-regulation
TK_Jak_TYK2_Y	P29597	TYK2	P29597	TYK2	Y1055	E1050G	1050	Missense	distal	-5	no	39.028	39.307	EPSD;PhosphoSitePlus	COSMIC	21.015	Up-regulation
TK_Jak_TYK2_Y	P17181	IFNAR1	P29597	TYK2	Y481	S483C	483	Missense	proximal	2	no	40.008	38.804	PhosphoSitePlus;EPSD	COSMIC	21.015	Down-regulation
TK_Jak_TYK2_Y	P17181	IFNAR1	P29597	TYK2	Y481	P474H	474	Missense	distal	-7	no	40.008	40.007	PhosphoSitePlus;EPSD	COSMIC	21.015	Down-regulation
TK_Jak_TYK2_Y	O15304	SIVA1	P29597	TYK2	Y53	G49R	49	Missense	distal	-4	no	41.028	40.662	EPSD;PhosphoSitePlus	COSMIC	21.015	Down-regulation
TK_Jak_TYK2_Y	P40763	STAT3	P29597	TYK2	Y640	Q643K	643	Missense	distal	3	no	44.286	44.310	PhosphoSitePlus	COSMIC	21.015	Up-regulation
TK_Jak_TYK2_Y	P40763	STAT3	P29597	TYK2	Y640	E638Q	638	Missense	proximal	-2	no	44.286	46.073	PhosphoSitePlus	COSMIC	21.015	Up-regulation
TK_Fak_PTK2B_Y	O15259	NPHP1	Q14289	PTK2B	Y46	L52S	52	Missense	distal	6	no	510.001	510.434	EPSD;PhosphoSitePlus	COSMIC	366.093	Up-regulation
TK_Fak_PTK2B_Y	O15259	NPHP1	Q14289	PTK2B	Y349	R346L	346	Missense	distal	-3	no	489.773	363.322	PhosphoSitePlus;EPSD	COSMIC	366.093	Loss
TK_Fak_PTK2B_Y	O15259	NPHP1	Q14289	PTK2B	Y349	Y349H	349	Missense	central	0	yes	489.773	0.000	PhosphoSitePlus;EPSD	COSMIC	366.093	Loss
TK_Fak_PTK2B_Y	O15259	NPHP1	Q14289	PTK2B	Y349	Q344K	344	Missense	distal	-5	no	489.773	488.983	PhosphoSitePlus;EPSD	COSMIC	366.093	Down-regulation
TK_Fak_PTK2B_Y	O15259	NPHP1	Q14289	PTK2B	Y349	G342R	342	Missense	distal	-7	no	489.773	488.113	PhosphoSitePlus;EPSD	COSMIC	366.093	Down-regulation
TK_Fak_PTK2B_Y	O15259	NPHP1	Q14289	PTK2B	Y721	Y721D	721	Missense	central	0	yes	395.880	0.000	EPSD	COSMIC	366.093	Loss
TK_Fak_PTK2B_Y	O15259	NPHP1	Q14289	PTK2B	Y721	E718Q	718	Missense	distal	-3	no	395.880	331.676	EPSD	COSMIC	366.093	Loss
TK_Fak_PTK2B_Y	O15259	NPHP1	Q14289	PTK2B	Y721	R728K	728	Missense	distal	7	no	395.880	394.901	EPSD	COSMIC	366.093	Down-regulation
TK_Fak_PTK2B_Y	O15259	NPHP1	Q14289	PTK2B	Y721	F714S	714	Missense	distal	-7	no	395.880	393.249	EPSD	COSMIC	366.093	Down-regulation
TK_Fak_PTK2B_Y	O15259	NPHP1	Q14289	PTK2B	Y721	F714L	714	Missense	distal	-7	no	395.880	396.038	EPSD	COSMIC	366.093	Up-regulation
TK_Fak_PTK2B_Y	O15259	NPHP1	Q14289	PTK2B	Y721	F723L	723	Missense	proximal	2	no	395.880	396.242	EPSD	COSMIC	366.093	Up-regulation
TK_Fak_PTK2B_Y	Q14247	CTTN	Q14289	PTK2B	Y84	G83D	83	Missense	proximal	-1	no	345.854	366.225	EPSD	COSMIC	366.093	Gain
TK_Fak_PTK2B_Y	Q14247	CTTN	Q14289	PTK2B	Y334	V330E	330	Missense	distal	-4	no	310.483	434.182	EPSD	COSMIC	366.093	Gain
TK_Fak_PTK2B_Y	Q14247	CTTN	Q14289	PTK2B	Y421	V420I	420	Missense	proximal	-1	no	622.353	634.258	EPSD;PhosphoSitePlus	COSMIC	366.093	Up-regulation
TK_Fak_PTK2B_Y	Q14247	CTTN	Q14289	PTK2B	Y421	S426F	426	Missense	distal	5	no	622.353	555.539	EPSD;PhosphoSitePlus	COSMIC	366.093	Down-regulation
TK_Fak_PTK2B_Y	Q14247	CTTN	Q14289	PTK2B	Y433	S438N	438	Missense	distal	5	no	368.960	346.459	EPSD	COSMIC	366.093	Loss
TK_Fak_PTK2B_Y	Q14247	CTTN	Q14289	PTK2B	Y433	T440P	440	Missense	distal	7	no	368.960	365.855	EPSD	COSMIC	366.093	Loss
TK_Fak_PTK2B_Y	Q14247	CTTN	Q14289	PTK2B	Y433	V437L	437	Missense	distal	4	no	368.960	371.623	EPSD	COSMIC	366.093	Up-regulation
TK_Fak_PTK2B_Y	Q14247	CTTN	Q14289	PTK2B	Y433	S426F	426	Missense	distal	-7	no	368.960	371.590	EPSD	COSMIC	366.093	Up-regulation
TK_Fak_PTK2B_Y	Q14247	CTTN	Q14289	PTK2B	Y446	T440P	440	Missense	distal	-6	no	392.624	394.299	EPSD	COSMIC	366.093	Up-regulation
TK_Fak_PTK2B_Y	Q14247	CTTN	Q14289	PTK2B	Y446	P442L	442	Missense	distal	-4	no	392.624	377.753	EPSD	COSMIC	366.093	Down-regulation
TK_Fak_PTK2B_Y	Q14247	CTTN	Q14289	PTK2B	Y446	E441K	441	Missense	distal	-5	no	392.624	388.114	EPSD	COSMIC	366.093	Down-regulation
TK_Fak_PTK2B_Y	Q14247	CTTN	Q14289	PTK2B	Y446	V445M	445	Missense	proximal	-1	no	392.624	387.770	EPSD	COSMIC	366.093	Down-regulation
TK_Fak_PTK2B_Y	Q14247	CTTN	Q14289	PTK2B	Y470	Y464C	464	Missense	distal	-6	no	658.507	658.175	EPSD;PhosphoSitePlus	COSMIC	366.093	Down-regulation
TK_Fak_PTK2B_Y	Q14247	CTTN	Q14289	PTK2B	Y470	A463T	463	Missense	distal	-7	no	658.507	657.143	EPSD;PhosphoSitePlus	COSMIC	366.093	Down-regulation
TK_Fak_PTK2B_Y	Q14247	CTTN	Q14289	PTK2B	Y470	P476L	476	Missense	distal	6	no	658.507	658.453	EPSD;PhosphoSitePlus	COSMIC;GDSC;CCLE	366.093	Down-regulation
TK_Fak_PTK2B_Y	Q02535	ID3	Q14289	PTK2B	Y48	N45S	45	Missense	distal	-3	no	329.177	404.600	EPSD;PhosphoSitePlus	COSMIC	366.093	Gain
TK_Fak_PTK2B_Y	O43294	TGFB1I1	Q14289	PTK2B	Y60	R67Q	67	Missense	distal	7	no	569.681	569.991	PhosphoSitePlus	COSMIC	366.093	Up-regulation
TK_Fak_PTK2B_Y	O43561	LAT	Q14289	PTK2B	Y110	V107L	107	Missense	distal	-3	no	334.622	368.716	EPSD	COSMIC	366.093	Gain
TK_Fak_PTK2B_Y	O43561	LAT	Q14289	PTK2B	Y220	R218W	218	Missense	proximal	-2	no	496.553	434.245	EPSD	COSMIC	366.093	Down-regulation
TK_Fak_PTK2B_Y	P37840	SNCA	Q14289	PTK2B	Y125	A124S	124	Missense	proximal	-1	no	505.058	514.648	PhosphoSitePlus	COSMIC	366.093	Up-regulation
TK_Fak_PTK2B_Y	P37840	SNCA	Q14289	PTK2B	Y125	E130V	130	Missense	distal	5	no	505.058	423.288	PhosphoSitePlus	COSMIC	366.093	Down-regulation
TK_Fak_PTK2B_Y	P37840	SNCA	Q14289	PTK2B	Y125	E130A	130	Missense	distal	5	no	505.058	461.706	PhosphoSitePlus	COSMIC	366.093	Down-regulation
TK_Fak_PTK2B_Y	P37840	SNCA	Q14289	PTK2B	Y125	D121Y	121	Missense	distal	-4	no	505.058	356.589	PhosphoSitePlus	COSMIC	366.093	Loss
TK_Fak_PTK2B_Y	P37840	SNCA	Q14289	PTK2B	Y125	E123K	123	Missense	proximal	-2	no	505.058	468.586	PhosphoSitePlus	COSMIC	366.093	Down-regulation
TK_Fak_PTK2B_Y	P37840	SNCA	Q14289	PTK2B	Y125	D121E	121	Missense	distal	-4	no	505.058	488.133	PhosphoSitePlus	COSMIC	366.093	Down-regulation
TK_Fak_PTK2B_Y	P37840	SNCA	Q14289	PTK2B	Y133	E130V	130	Missense	distal	-3	no	429.398	244.473	EPSD	COSMIC	366.093	Loss
TK_Fak_PTK2B_Y	P37840	SNCA	Q14289	PTK2B	Y133	D135E	135	Missense	proximal	2	no	429.398	428.930	EPSD	COSMIC;GDSC;CCLE	366.093	Down-regulation
TK_Fak_PTK2B_Y	P37840	SNCA	Q14289	PTK2B	Y133	E130A	130	Missense	distal	-3	no	429.398	324.455	EPSD	COSMIC	366.093	Loss
TK_Fak_PTK2B_Y	Q14289	PTK2B	Q14289	PTK2B	Y579	T585I	585	Missense	distal	6	no	391.776	391.510	EPSD	COSMIC	366.093	Down-regulation
TK_Fak_PTK2B_Y	Q14289	PTK2B	Q14289	PTK2B	Y579	E577K	577	Missense	proximal	-2	no	391.776	355.304	EPSD	COSMIC;GDSC;CCLE	366.093	Loss
TK_Fak_PTK2B_Y	Q14289	PTK2B	Q14289	PTK2B	Y580	T585I	585	Missense	distal	5	no	443.113	382.090	EPSD	COSMIC	366.093	Down-regulation
TK_Fak_PTK2B_Y	Q14289	PTK2B	Q14289	PTK2B	Y580	E577K	577	Missense	distal	-3	no	443.113	366.794	EPSD	COSMIC;GDSC;CCLE	366.093	Down-regulation
TK_Fak_PTK2B_Y	Q14289	PTK2B	Q14289	PTK2B	Y683	C677Y	677	Missense	distal	-6	no	377.698	378.030	EPSD	COSMIC	366.093	Up-regulation
TK_Fak_PTK2B_Y	Q14289	PTK2B	Q14289	PTK2B	Y722	P726L	726	Missense	distal	4	no	441.541	434.170	EPSD	COSMIC	366.093	Down-regulation
TK_Fak_PTK2B_Y	Q14289	PTK2B	Q14289	PTK2B	Y722	P724T	724	Missense	proximal	2	no	441.541	443.918	EPSD	COSMIC	366.093	Up-regulation
TK_Fak_PTK2B_Y	Q05397	PTK2	Q14289	PTK2B	Y397	S390A	390	Missense	distal	-7	no	496.167	497.099	EPSD	COSMIC	366.093	Up-regulation
TK_Fak_PTK2B_Y	Q05397	PTK2	Q14289	PTK2B	Y397	D402V	402	Missense	distal	5	no	496.167	418.606	EPSD	COSMIC	366.093	Down-regulation
TK_Fak_PTK2B_Y	Q05397	PTK2	Q14289	PTK2B	Y397	E404A	404	Missense	distal	7	no	496.167	493.858	EPSD	COSMIC	366.093	Down-regulation
TK_Fak_PTK2B_Y	Q05397	PTK2	Q14289	PTK2B	Y397	V391A	391	Missense	distal	-6	no	496.167	493.535	EPSD	COSMIC	366.093	Down-regulation
TK_Fak_PTK2B_Y	Q05397	PTK2	Q14289	PTK2B	Y407	D402V	402	Missense	distal	-5	no	679.931	670.873	PhosphoSitePlus	COSMIC	366.093	Down-regulation
TK_Fak_PTK2B_Y	Q05397	PTK2	Q14289	PTK2B	Y407	D405G	405	Missense	proximal	-2	no	679.931	623.802	PhosphoSitePlus	COSMIC	366.093	Down-regulation
TK_Fak_PTK2B_Y	Q05397	PTK2	Q14289	PTK2B	Y407	R413S	413	Missense	distal	6	no	679.931	680.034	PhosphoSitePlus	COSMIC	366.093	Up-regulation
TK_Fak_PTK2B_Y	Q05397	PTK2	Q14289	PTK2B	Y407	E404A	404	Missense	distal	-3	no	679.931	574.988	PhosphoSitePlus	COSMIC	366.093	Down-regulation
TK_Fak_PTK2B_Y	Q05397	PTK2	Q14289	PTK2B	Y441	P447S	447	Missense	distal	6	no	421.327	421.706	EPSD	COSMIC	366.093	Up-regulation
TK_Fak_PTK2B_Y	Q05397	PTK2	Q14289	PTK2B	Y441	S443R	443	Missense	proximal	2	no	421.327	420.660	EPSD	COSMIC	366.093	Down-regulation
TK_Fak_PTK2B_Y	Q05397	PTK2	Q14289	PTK2B	Y441	Y441F	441	Missense	central	0	yes	421.327	0.000	EPSD	COSMIC	366.093	Loss
TK_Fak_PTK2B_Y	Q05397	PTK2	Q14289	PTK2B	Y576	R569L	569	Missense	distal	-7	no	558.333	559.757	EPSD	COSMIC	366.093	Up-regulation
TK_Fak_PTK2B_Y	Q05397	PTK2	Q14289	PTK2B	Y576	A579V	579	Missense	distal	3	no	558.333	552.123	EPSD	COSMIC	366.093	Down-regulation
TK_Fak_PTK2B_Y	Q05397	PTK2	Q14289	PTK2B	Y577	A579V	579	Missense	proximal	2	no	433.832	431.507	EPSD	COSMIC	366.093	Down-regulation
TK_Fak_PTK2B_Y	P29474	NOS3	Q14289	PTK2B	Y657	P658L	658	Missense	proximal	1	no	449.011	445.208	PhosphoSitePlus	COSMIC;CCLE	366.093	Down-regulation
TK_Fak_PTK2B_Y	P29474	NOS3	Q14289	PTK2B	Y657	G651E	651	Missense	distal	-6	no	449.011	446.919	PhosphoSitePlus	COSMIC	366.093	Down-regulation
TK_Fak_PTK2B_Y	P29474	NOS3	Q14289	PTK2B	Y657	S654P	654	Missense	distal	-3	no	449.011	325.183	PhosphoSitePlus	COSMIC	366.093	Loss
AGC_RSK_RSKp70_RPS6KB2_ST	Q15633	TARBP2	Q9UBS0	RPS6KB2	S184	Q182R	182	Missense	proximal	-2	no	4.100	4.250	EPSD	COSMIC	4.103	Gain
AGC_RSK_RSKp70_RPS6KB2_ST	Q15633	TARBP2	Q9UBS0	RPS6KB2	S283	I276T	276	Missense	distal	-7	no	10.205	10.044	PhosphoSitePlus	COSMIC	4.103	Down-regulation
AGC_RSK_RSKp70_RPS6KB2_ST	Q15633	TARBP2	Q9UBS0	RPS6KB2	S283	S278Y	278	Missense	distal	-5	no	10.205	10.137	PhosphoSitePlus	COSMIC	4.103	Down-regulation
AGC_RSK_RSKp70_RPS6KB2_ST	Q15633	TARBP2	Q9UBS0	RPS6KB2	S283	L279I	279	Missense	distal	-4	no	10.205	10.092	PhosphoSitePlus	COSMIC	4.103	Down-regulation
AGC_RSK_RSKp70_RPS6KB2_ST	P04792	HSPB1	Q9UBS0	RPS6KB2	S15	P14S	14	Missense	proximal	-1	no	5.741	6.464	EPSD	COSMIC	4.103	Up-regulation
AGC_RSK_RSKp70_RPS6KB2_ST	P04792	HSPB1	Q9UBS0	RPS6KB2	S15	R20W	20	Missense	distal	5	no	5.741	5.750	EPSD	COSMIC	4.103	Up-regulation
AGC_RSK_RSKp70_RPS6KB2_ST	P04792	HSPB1	Q9UBS0	RPS6KB2	S15	R20Q	20	Missense	distal	5	no	5.741	5.723	EPSD	COSMIC	4.103	Down-regulation
AGC_RSK_RSKp70_RPS6KB2_ST	P04792	HSPB1	Q9UBS0	RPS6KB2	S15	F8L	8	Missense	distal	-7	no	5.741	5.618	EPSD	COSMIC	4.103	Down-regulation
AGC_RSK_RSKp70_RPS6KB2_ST	P04792	HSPB1	Q9UBS0	RPS6KB2	S78	R75C	75	Missense	distal	-3	no	10.348	5.055	PhosphoSitePlus;EPSD	COSMIC	4.103	Down-regulation
AGC_RSK_RSKp70_RPS6KB2_ST	P04792	HSPB1	Q9UBS0	RPS6KB2	S82	R75C	75	Missense	distal	-7	no	9.866	9.967	EPSD;PhosphoSitePlus	COSMIC	4.103	Up-regulation
AGC_RSK_RSKp70_RPS6KB2_ST	P04792	HSPB1	Q9UBS0	RPS6KB2	T139	R140Q	140	Missense	proximal	1	no	6.546	6.635	EPSD	COSMIC	4.103	Up-regulation
AGC_RSK_RSKp70_RPS6KB2_ST	P04792	HSPB1	Q9UBS0	RPS6KB2	T143	R140Q	140	Missense	distal	-3	no	6.518	1.748	EPSD	COSMIC	4.103	Loss
AGC_RSK_RSKp70_RPS6KB2_ST	P49841	GSK3B	Q9UBS0	RPS6KB2	T7	S9F	9	Missense	proximal	2	no	4.056	4.263	EPSD	COSMIC	4.103	Gain
AGC_RSK_RSKp70_RPS6KB2_ST	P49841	GSK3B	Q9UBS0	RPS6KB2	S9	S9F	9	Missense	central	0	yes	9.449	0.000	PhosphoSitePlus	COSMIC	4.103	Loss
AGC_RSK_RSKp70_RPS6KB2_ST	P49841	GSK3B	Q9UBS0	RPS6KB2	S9	P16A	16	Missense	distal	7	no	9.449	9.450	PhosphoSitePlus	COSMIC	4.103	Up-regulation
AGC_RSK_RSKp70_RPS6KB2_ST	P49841	GSK3B	Q9UBS0	RPS6KB2	S9	S2P	2	Missense	distal	-7	no	9.449	9.620	PhosphoSitePlus	COSMIC	4.103	Up-regulation
AGC_RSK_RSKp70_RPS6KB2_ST	P49841	GSK3B	Q9UBS0	RPS6KB2	S147	P154S	154	Missense	distal	7	no	5.899	5.903	EPSD	COSMIC	4.103	Up-regulation
AGC_RSK_RSKp70_RPS6KB2_ST	P49841	GSK3B	Q9UBS0	RPS6KB2	S147	Y146C	146	Missense	proximal	-1	no	5.899	6.511	EPSD	COSMIC	4.103	Up-regulation
AGC_RSK_RSKp70_RPS6KB2_ST	P49841	GSK3B	Q9UBS0	RPS6KB2	S147	R148Q	148	Missense	proximal	1	no	5.899	5.988	EPSD	COSMIC	4.103	Up-regulation
AGC_RSK_RSKp70_RPS6KB2_ST	P49841	GSK3B	Q9UBS0	RPS6KB2	S147	S147N	147	Missense	central	0	yes	5.899	0.000	EPSD	COSMIC	4.103	Loss
AGC_RSK_RSKp70_RPS6KB2_ST	P49841	GSK3B	Q9UBS0	RPS6KB2	S147	Y140C	140	Missense	distal	-7	no	5.899	5.912	EPSD	COSMIC	4.103	Up-regulation
AGC_RSK_RSKp70_RPS6KB2_ST	P49841	GSK3B	Q9UBS0	RPS6KB2	S147	A143G	143	Missense	distal	-4	no	5.899	5.900	EPSD	COSMIC	4.103	Up-regulation
AGC_RSK_RSKp70_RPS6KB2_ST	P49841	GSK3B	Q9UBS0	RPS6KB2	S147	R141S	141	Missense	distal	-6	no	5.899	5.853	EPSD	COSMIC	4.103	Down-regulation
AGC_RSK_RSKp70_RPS6KB2_ST	P49841	GSK3B	Q9UBS0	RPS6KB2	T408	R405S	405	Missense	distal	-3	no	4.930	0.120	EPSD	COSMIC	4.103	Loss
AGC_RSK_RSKp70_RPS6KB2_ST	P49841	GSK3B	Q9UBS0	RPS6KB2	T408	T402I	402	Missense	distal	-6	no	4.930	5.082	EPSD	COSMIC	4.103	Up-regulation
AGC_RSK_RSKp70_RPS6KB2_ST	P49841	GSK3B	Q9UBS0	RPS6KB2	T408	R405H	405	Missense	distal	-3	no	4.930	0.639	EPSD	COSMIC;CCLE	4.103	Loss
AGC_RSK_RSKp70_RPS6KB2_ST	P05783	KRT18	Q9UBS0	RPS6KB2	S30	S23G	23	Missense	distal	-7	no	5.083	5.301	EPSD	COSMIC	4.103	Up-regulation
AGC_RSK_RSKp70_RPS6KB2_ST	P05783	KRT18	Q9UBS0	RPS6KB2	S53	G59R	59	Missense	distal	6	no	9.837	9.710	PhosphoSitePlus	COSMIC	4.103	Down-regulation
AGC_RSK_RSKp70_RPS6KB2_ST	P05783	KRT18	Q9UBS0	RPS6KB2	S53	G59E	59	Missense	distal	6	no	9.837	9.710	PhosphoSitePlus	COSMIC	4.103	Down-regulation
AGC_RSK_RSKp70_RPS6KB2_ST	P05783	KRT18	Q9UBS0	RPS6KB2	S93	R90C	90	Missense	distal	-3	no	7.353	2.060	EPSD	COSMIC	4.103	Loss
AGC_RSK_RSKp70_RPS6KB2_ST	P05783	KRT18	Q9UBS0	RPS6KB2	S93	S100R	100	Missense	distal	7	no	7.353	7.350	EPSD	COSMIC	4.103	Down-regulation
AGC_RSK_RSKp70_RPS6KB2_ST	P05783	KRT18	Q9UBS0	RPS6KB2	S100	S100R	100	Missense	central	0	yes	6.236	0.000	EPSD	COSMIC	4.103	Loss
AGC_RSK_RSKp70_RPS6KB2_ST	P05783	KRT18	Q9UBS0	RPS6KB2	T103	S100R	100	Missense	distal	-3	no	2.234	7.044	EPSD	COSMIC	4.103	Gain
AGC_RSK_RSKp70_RPS6KB2_ST	O00418	EEF2K	Q9UBS0	RPS6KB2	S61	V56L	56	Missense	distal	-5	no	4.142	4.140	EPSD	COSMIC	4.103	Down-regulation
AGC_RSK_RSKp70_RPS6KB2_ST	O00418	EEF2K	Q9UBS0	RPS6KB2	S135	P137L	137	Missense	proximal	2	no	4.366	4.390	EPSD	COSMIC	4.103	Up-regulation
AGC_RSK_RSKp70_RPS6KB2_ST	O00418	EEF2K	Q9UBS0	RPS6KB2	S135	S135C	135	Missense	central	0	yes	4.366	0.000	EPSD	COSMIC	4.103	Loss
AGC_RSK_RSKp70_RPS6KB2_ST	O00418	EEF2K	Q9UBS0	RPS6KB2	S241	S243F	243	Missense	proximal	2	no	3.951	4.157	EPSD	COSMIC	4.103	Gain
AGC_RSK_RSKp70_RPS6KB2_ST	O00418	EEF2K	Q9UBS0	RPS6KB2	S243	Y239H	239	Missense	distal	-4	no	4.356	4.363	EPSD	COSMIC	4.103	Up-regulation
AGC_RSK_RSKp70_RPS6KB2_ST	O00418	EEF2K	Q9UBS0	RPS6KB2	S243	S243P	243	Missense	central	0	yes	4.356	0.000	EPSD	COSMIC	4.103	Loss
AGC_RSK_RSKp70_RPS6KB2_ST	O00418	EEF2K	Q9UBS0	RPS6KB2	S243	S243F	243	Missense	central	0	yes	4.356	0.000	EPSD	COSMIC	4.103	Loss
AGC_RSK_RSKp70_RPS6KB2_ST	O00418	EEF2K	Q9UBS0	RPS6KB2	S366	T364N	364	Missense	proximal	-2	no	9.928	9.234	PhosphoSitePlus	COSMIC	4.103	Down-regulation
AGC_RSK_RSKp70_RPS6KB2_ST	O00418	EEF2K	Q9UBS0	RPS6KB2	S377	E383D	383	Missense	distal	6	no	6.398	6.332	EPSD	COSMIC	4.103	Down-regulation
AGC_RSK_RSKp70_RPS6KB2_ST	O00418	EEF2K	Q9UBS0	RPS6KB2	S377	S377L	377	Missense	central	0	yes	6.398	0.000	EPSD	COSMIC	4.103	Loss
AGC_RSK_RSKp70_RPS6KB2_ST	O00418	EEF2K	Q9UBS0	RPS6KB2	S377	P375S	375	Missense	proximal	-2	no	6.398	7.266	EPSD	COSMIC	4.103	Up-regulation
AGC_RSK_RSKp70_RPS6KB2_ST	P09651	HNRNPA1	Q9UBS0	RPS6KB2	S6	S6Y	6	Missense	central	0	yes	7.662	0.000	EPSD;PhosphoSitePlus	COSMIC	4.103	Loss
AGC_RSK_RSKp70_RPS6KB2_ST	P09651	HNRNPA1	Q9UBS0	RPS6KB2	S6	E5K	5	Missense	proximal	-1	no	7.662	7.371	EPSD;PhosphoSitePlus	COSMIC	4.103	Down-regulation
AGC_RSK_RSKp70_RPS6KB2_ST	P09651	HNRNPA1	Q9UBS0	RPS6KB2	S22	G19R	19	Missense	distal	-3	no	2.790	7.957	EPSD	COSMIC	4.103	Gain
AGC_RSK_RSKp70_RPS6KB2_ST	P09651	HNRNPA1	Q9UBS0	RPS6KB2	S197	G203C	203	Missense	distal	6	no	6.020	5.867	EPSD	COSMIC	4.103	Down-regulation
AGC_RSK_RSKp70_RPS6KB2_ST	P09651	HNRNPA1	Q9UBS0	RPS6KB2	S199	G203C	203	Missense	distal	4	no	7.042	7.067	EPSD	COSMIC	4.103	Up-regulation
AGC_RSK_RSKp70_RPS6KB2_ST	Q6R327	RICTOR	Q9UBS0	RPS6KB2	S21	E23D	23	Missense	proximal	2	no	6.466	6.420	EPSD	COSMIC;GDSC;CCLE	4.103	Down-regulation
AGC_RSK_RSKp70_RPS6KB2_ST	Q6R327	RICTOR	Q9UBS0	RPS6KB2	S21	P27S	27	Missense	distal	6	no	6.466	6.219	EPSD	COSMIC	4.103	Down-regulation
AGC_RSK_RSKp70_RPS6KB2_ST	Q6R327	RICTOR	Q9UBS0	RPS6KB2	S21	R14Q	14	Missense	distal	-7	no	6.466	6.546	EPSD	COSMIC	4.103	Up-regulation
AGC_RSK_RSKp70_RPS6KB2_ST	Q6R327	RICTOR	Q9UBS0	RPS6KB2	S21	G17E	17	Missense	distal	-4	no	6.466	6.469	EPSD	COSMIC	4.103	Up-regulation
AGC_RSK_RSKp70_RPS6KB2_ST	Q6R327	RICTOR	Q9UBS0	RPS6KB2	S35	E40D	40	Missense	distal	5	no	5.932	5.902	EPSD	COSMIC	4.103	Down-regulation
AGC_RSK_RSKp70_RPS6KB2_ST	Q6R327	RICTOR	Q9UBS0	RPS6KB2	S35	D29E	29	Missense	distal	-6	no	5.932	6.028	EPSD	COSMIC	4.103	Up-regulation
AGC_RSK_RSKp70_RPS6KB2_ST	Q6R327	RICTOR	Q9UBS0	RPS6KB2	S383	P378L	378	Missense	distal	-5	no	6.174	6.181	EPSD	COSMIC	4.103	Up-regulation
AGC_RSK_RSKp70_RPS6KB2_ST	Q6R327	RICTOR	Q9UBS0	RPS6KB2	S383	R384G	384	Missense	proximal	1	no	6.174	6.425	EPSD	COSMIC	4.103	Up-regulation
AGC_RSK_RSKp70_RPS6KB2_ST	Q6R327	RICTOR	Q9UBS0	RPS6KB2	S383	R380L	380	Missense	distal	-3	no	6.174	0.159	EPSD	COSMIC	4.103	Loss
AGC_RSK_RSKp70_RPS6KB2_ST	Q6R327	RICTOR	Q9UBS0	RPS6KB2	S383	L377I	377	Missense	distal	-6	no	6.174	6.233	EPSD	COSMIC	4.103	Up-regulation
AGC_RSK_RSKp70_RPS6KB2_ST	Q6R327	RICTOR	Q9UBS0	RPS6KB2	S383	H379Y	379	Missense	distal	-4	no	6.174	6.168	EPSD	COSMIC	4.103	Down-regulation
AGC_RSK_RSKp70_RPS6KB2_ST	Q6R327	RICTOR	Q9UBS0	RPS6KB2	S585	K582E	582	Missense	distal	-3	no	4.137	1.474	EPSD	COSMIC	4.103	Loss
AGC_RSK_RSKp70_RPS6KB2_ST	Q6R327	RICTOR	Q9UBS0	RPS6KB2	S810	S816F	816	Missense	distal	6	no	7.073	7.438	EPSD	COSMIC	4.103	Up-regulation
AGC_RSK_RSKp70_RPS6KB2_ST	Q6R327	RICTOR	Q9UBS0	RPS6KB2	S810	L804V	804	Missense	distal	-6	no	7.073	7.145	EPSD	COSMIC	4.103	Up-regulation
AGC_RSK_RSKp70_RPS6KB2_ST	Q6R327	RICTOR	Q9UBS0	RPS6KB2	S1035	P1041S	1041	Missense	distal	6	no	6.417	6.169	EPSD	COSMIC;GDSC;CCLE	4.103	Down-regulation
AGC_RSK_RSKp70_RPS6KB2_ST	Q6R327	RICTOR	Q9UBS0	RPS6KB2	S1035	T1029A	1029	Missense	distal	-6	no	6.417	6.530	EPSD	COSMIC	4.103	Up-regulation
AGC_RSK_RSKp70_RPS6KB2_ST	Q6R327	RICTOR	Q9UBS0	RPS6KB2	S1122	P1115A	1115	Missense	distal	-7	no	5.186	5.239	EPSD	COSMIC	4.103	Up-regulation
AGC_RSK_RSKp70_RPS6KB2_ST	Q6R327	RICTOR	Q9UBS0	RPS6KB2	T1133	T1135A	1135	Missense	proximal	2	no	4.380	4.499	EPSD	COSMIC	4.103	Up-regulation
AGC_RSK_RSKp70_RPS6KB2_ST	Q6R327	RICTOR	Q9UBS0	RPS6KB2	T1133	D1140Y	1140	Missense	distal	7	no	4.380	4.379	EPSD	COSMIC	4.103	Down-regulation
AGC_RSK_RSKp70_RPS6KB2_ST	Q6R327	RICTOR	Q9UBS0	RPS6KB2	T1135	D1140E	1140	Missense	distal	5	no	9.512	9.543	PhosphoSitePlus	COSMIC	4.103	Up-regulation
AGC_RSK_RSKp70_RPS6KB2_ST	Q6R327	RICTOR	Q9UBS0	RPS6KB2	T1135	T1135A	1135	Missense	central	0	yes	9.512	0.000	PhosphoSitePlus	COSMIC	4.103	Loss
AGC_RSK_RSKp70_RPS6KB2_ST	Q6R327	RICTOR	Q9UBS0	RPS6KB2	T1135	D1140Y	1140	Missense	distal	5	no	9.512	9.527	PhosphoSitePlus	COSMIC	4.103	Up-regulation
AGC_RSK_RSKp70_RPS6KB2_ST	Q6R327	RICTOR	Q9UBS0	RPS6KB2	T1198	T1198A	1198	Missense	central	0	yes	4.999	0.000	EPSD	COSMIC	4.103	Loss
AGC_RSK_RSKp70_RPS6KB2_ST	Q6R327	RICTOR	Q9UBS0	RPS6KB2	S1219	K1214Q	1214	Missense	distal	-5	no	8.046	7.948	EPSD	COSMIC	4.103	Down-regulation
AGC_RSK_RSKp70_RPS6KB2_ST	Q6R327	RICTOR	Q9UBS0	RPS6KB2	S1219	M1213L	1213	Missense	distal	-6	no	8.046	8.041	EPSD	COSMIC	4.103	Down-regulation
AGC_RSK_RSKp70_RPS6KB2_ST	Q6R327	RICTOR	Q9UBS0	RPS6KB2	S1219	Q1218P	1218	Missense	proximal	-1	no	8.046	7.904	EPSD	COSMIC	4.103	Down-regulation
AGC_RSK_RSKp70_RPS6KB2_ST	Q6R327	RICTOR	Q9UBS0	RPS6KB2	S1284	N1283S	1283	Missense	proximal	-1	no	3.388	4.172	EPSD	COSMIC	4.103	Gain
AGC_RSK_RSKp70_RPS6KB2_ST	Q6R327	RICTOR	Q9UBS0	RPS6KB2	S1302	A1309V	1309	Missense	distal	7	no	5.813	5.812	EPSD	COSMIC	4.103	Down-regulation
AGC_RSK_RSKp70_RPS6KB2_ST	Q6R327	RICTOR	Q9UBS0	RPS6KB2	S1302	P1297S	1297	Missense	distal	-5	no	5.813	5.923	EPSD	COSMIC	4.103	Up-regulation
AGC_RSK_RSKp70_RPS6KB2_ST	Q6R327	RICTOR	Q9UBS0	RPS6KB2	S1302	R1299K	1299	Missense	distal	-3	no	5.813	3.107	EPSD	COSMIC	4.103	Loss
AGC_RSK_RSKp70_RPS6KB2_ST	Q6R327	RICTOR	Q9UBS0	RPS6KB2	S1385	R1379K	1379	Missense	distal	-6	no	4.713	4.794	EPSD	COSMIC	4.103	Up-regulation
AGC_RSK_RSKp70_RPS6KB2_ST	Q6R327	RICTOR	Q9UBS0	RPS6KB2	S1385	R1379S	1379	Missense	distal	-6	no	4.713	4.667	EPSD	COSMIC	4.103	Down-regulation
AGC_RSK_RSKp70_RPS6KB2_ST	Q6R327	RICTOR	Q9UBS0	RPS6KB2	S1385	L1384S	1384	Missense	proximal	-1	no	4.713	3.955	EPSD	COSMIC;GDSC;CCLE	4.103	Loss
AGC_RSK_RSKp70_RPS6KB2_ST	Q6R327	RICTOR	Q9UBS0	RPS6KB2	S1385	F1380L	1380	Missense	distal	-5	no	4.713	4.755	EPSD	COSMIC	4.103	Up-regulation
AGC_RSK_RSKp70_RPS6KB2_ST	Q6R327	RICTOR	Q9UBS0	RPS6KB2	S1408	R1410W	1410	Missense	proximal	2	no	7.257	7.424	EPSD	COSMIC	4.103	Up-regulation
AGC_RSK_RSKp70_RPS6KB2_ST	Q6R327	RICTOR	Q9UBS0	RPS6KB2	S1408	S1406F	1406	Missense	proximal	-2	no	7.257	6.005	EPSD	COSMIC	4.103	Down-regulation
AGC_RSK_RSKp70_RPS6KB2_ST	Q6R327	RICTOR	Q9UBS0	RPS6KB2	S1408	T1402P	1402	Missense	distal	-6	no	7.257	7.365	EPSD	COSMIC	4.103	Up-regulation
AGC_RSK_RSKp70_RPS6KB2_ST	Q6R327	RICTOR	Q9UBS0	RPS6KB2	S1408	R1410Q	1410	Missense	proximal	2	no	7.257	7.418	EPSD	COSMIC	4.103	Up-regulation
AGC_RSK_RSKp70_RPS6KB2_ST	Q6R327	RICTOR	Q9UBS0	RPS6KB2	S1479	N1478S	1478	Missense	proximal	-1	no	3.519	4.303	EPSD	COSMIC	4.103	Gain
TK_Src_SrcA_FGR_Y	P09917	ALOX5	P09769	FGR	Y75	D80N	80	Missense	distal	5	no	7.615	8.285	EPSD	COSMIC	5.114	Up-regulation
TK_Src_SrcA_FGR_Y	P09917	ALOX5	P09769	FGR	Y75	W76L	76	Missense	proximal	1	no	7.615	8.298	EPSD	COSMIC	5.114	Up-regulation
TK_Src_SrcA_FGR_Y	Q05397	PTK2	P09769	FGR	Y397	S390A	390	Missense	distal	-7	no	10.061	9.993	EPSD;PhosphoSitePlus	COSMIC	5.114	Down-regulation
TK_Src_SrcA_FGR_Y	Q05397	PTK2	P09769	FGR	Y397	D402V	402	Missense	distal	5	no	10.061	11.636	EPSD;PhosphoSitePlus	COSMIC	5.114	Up-regulation
TK_Src_SrcA_FGR_Y	Q05397	PTK2	P09769	FGR	Y397	E404A	404	Missense	distal	7	no	10.061	8.276	EPSD;PhosphoSitePlus	COSMIC	5.114	Down-regulation
TK_Src_SrcA_FGR_Y	Q05397	PTK2	P09769	FGR	Y397	V391A	391	Missense	distal	-6	no	10.061	10.107	EPSD;PhosphoSitePlus	COSMIC	5.114	Up-regulation
TK_Src_SrcA_FGR_Y	Q05397	PTK2	P09769	FGR	Y441	P447S	447	Missense	distal	6	no	5.191	4.705	EPSD	COSMIC	5.114	Loss
TK_Src_SrcA_FGR_Y	Q05397	PTK2	P09769	FGR	Y441	S443R	443	Missense	proximal	2	no	5.191	4.600	EPSD	COSMIC	5.114	Loss
TK_Src_SrcA_FGR_Y	Q05397	PTK2	P09769	FGR	Y441	Y441F	441	Missense	central	0	yes	5.191	0.000	EPSD	COSMIC	5.114	Loss
TK_Src_SrcA_FGR_Y	Q05397	PTK2	P09769	FGR	Y576	R569L	569	Missense	distal	-7	no	12.266	12.269	EPSD;PhosphoSitePlus	COSMIC	5.114	Up-regulation
TK_Src_SrcA_FGR_Y	Q05397	PTK2	P09769	FGR	Y576	A579V	579	Missense	distal	3	no	12.266	12.224	EPSD;PhosphoSitePlus	COSMIC	5.114	Down-regulation
TK_Src_SrcA_FGR_Y	Q05397	PTK2	P09769	FGR	Y925	G930C	930	Missense	distal	5	no	10.388	9.819	PhosphoSitePlus;EPSD	COSMIC	5.114	Down-regulation
TK_Src_SrcA_FGR_Y	Q05397	PTK2	P09769	FGR	Y925	D918G	918	Missense	distal	-7	no	10.388	10.407	PhosphoSitePlus;EPSD	COSMIC	5.114	Up-regulation
TK_Src_SrcA_FGR_Y	Q05397	PTK2	P09769	FGR	Y925	E926K	926	Missense	proximal	1	no	10.388	9.820	PhosphoSitePlus;EPSD	COSMIC	5.114	Down-regulation
TK_Src_SrcA_FGR_Y	Q05397	PTK2	P09769	FGR	Y925	Y925C	925	Missense	central	0	yes	10.388	0.000	PhosphoSitePlus;EPSD	COSMIC	5.114	Loss
TK_Src_SrcA_FGR_Y	Q05397	PTK2	P09769	FGR	Y925	R919L	919	Missense	distal	-6	no	10.388	10.353	PhosphoSitePlus;EPSD	COSMIC	5.114	Down-regulation
TK_Src_SrcA_FGR_Y	Q05397	PTK2	P09769	FGR	Y925	R919Q	919	Missense	distal	-6	no	10.388	10.391	PhosphoSitePlus;EPSD	COSMIC	5.114	Up-regulation
TK_Src_SrcA_FGR_Y	Q9UHD2	TBK1	P09769	FGR	Y340	S347Y	347	Missense	distal	7	no	5.205	4.655	EPSD	COSMIC	5.114	Loss
TK_Src_SrcA_FGR_Y	Q9UHD2	TBK1	P09769	FGR	Y354	S347Y	347	Missense	distal	-7	no	9.835	9.792	PhosphoSitePlus;EPSD	COSMIC	5.114	Down-regulation
TK_Src_SrcA_FGR_Y	Q9UHD2	TBK1	P09769	FGR	Y354	R357Q	357	Missense	distal	3	no	9.835	9.823	PhosphoSitePlus;EPSD	COSMIC	5.114	Down-regulation
TK_Src_SrcA_FGR_Y	Q9UHD2	TBK1	P09769	FGR	Y394	S398F	398	Missense	distal	4	no	10.242	9.634	EPSD;PhosphoSitePlus	COSMIC	5.114	Down-regulation
TK_Src_SrcA_FGR_Y	Q9UHD2	TBK1	P09769	FGR	Y394	I390V	390	Missense	distal	-4	no	10.242	10.072	EPSD;PhosphoSitePlus	COSMIC	5.114	Down-regulation
TK_Src_SrcA_FGR_Y	Q9UHD2	TBK1	P09769	FGR	Y435	G442E	442	Missense	distal	7	no	3.219	5.330	EPSD	COSMIC	5.114	Gain
TK_Src_SrcA_FGR_Y	Q9UHD2	TBK1	P09769	FGR	Y577	R573L	573	Missense	distal	-4	no	7.400	6.179	EPSD	COSMIC	5.114	Down-regulation
TK_Src_SrcA_FGR_Y	Q9UHD2	TBK1	P09769	FGR	Y577	Y577C	577	Missense	central	0	yes	7.400	0.000	EPSD	COSMIC	5.114	Loss
TK_Src_SRM_Y	Q13882	PTK6	Q13882	PTK6	Y114	S117P	117	Missense	distal	3	no	0.999	1.853	EPSD	COSMIC	1.179	Gain
TK_Src_SRM_Y	Q13882	PTK6	Q13882	PTK6	Y342	I337M	337	Missense	distal	-5	no	1.301	1.259	EPSD;PhosphoSitePlus	COSMIC	1.179	Down-regulation
TK_Src_SRM_Y	Q13882	PTK6	Q13882	PTK6	Y342	R335S	335	Missense	distal	-7	no	1.301	1.388	EPSD;PhosphoSitePlus	COSMIC	1.179	Up-regulation
TK_Src_SRM_Y	Q13882	PTK6	Q13882	PTK6	Y342	L343F	343	Missense	proximal	1	no	1.301	1.244	EPSD;PhosphoSitePlus	COSMIC	1.179	Down-regulation
TK_Src_SRM_Y	Q13882	PTK6	Q13882	PTK6	Y447	P450L	450	Missense	distal	3	no	3.022	2.025	PhosphoSitePlus;EPSD	COSMIC	1.179	Down-regulation
TK_Src_SRM_PTK6_Y	Q13882	PTK6	Q13882	PTK6	Y13	L16F	16	Missense	distal	3	no	21.269	11.872	EPSD	COSMIC	13.984	Loss
TK_Src_SRM_PTK6_Y	Q13882	PTK6	Q13882	PTK6	Y114	P110S	110	Missense	distal	-4	no	19.659	20.100	EPSD	COSMIC;GDSC;CCLE	13.984	Up-regulation
TK_Src_SRM_PTK6_Y	Q13882	PTK6	Q13882	PTK6	Y114	R119Q	119	Missense	distal	5	no	19.659	15.443	EPSD	COSMIC	13.984	Down-regulation
TK_Src_SRM_PTK6_Y	Q13882	PTK6	Q13882	PTK6	Y114	S117P	117	Missense	distal	3	no	19.659	32.318	EPSD	COSMIC	13.984	Up-regulation
TK_Src_SRM_PTK6_Y	Q13882	PTK6	Q13882	PTK6	Y114	E108K	108	Missense	distal	-6	no	19.659	19.148	EPSD	COSMIC	13.984	Down-regulation
TK_Src_SRM_PTK6_Y	Q13882	PTK6	Q13882	PTK6	Y342	I337M	337	Missense	distal	-5	no	26.986	25.682	EPSD;PhosphoSitePlus	COSMIC	13.984	Down-regulation
TK_Src_SRM_PTK6_Y	Q13882	PTK6	Q13882	PTK6	Y342	R335S	335	Missense	distal	-7	no	26.986	28.335	EPSD;PhosphoSitePlus	COSMIC	13.984	Up-regulation
TK_Src_SRM_PTK6_Y	Q13882	PTK6	Q13882	PTK6	Y342	L343F	343	Missense	proximal	1	no	26.986	25.789	EPSD;PhosphoSitePlus	COSMIC	13.984	Down-regulation
TK_Src_SRM_PTK6_Y	Q13882	PTK6	Q13882	PTK6	Y351	A355S	355	Missense	distal	4	no	21.722	21.591	EPSD	COSMIC	13.984	Down-regulation
TK_Src_SRM_PTK6_Y	Q13882	PTK6	Q13882	PTK6	Y447	P450L	450	Missense	distal	3	no	39.672	27.545	PhosphoSitePlus;EPSD	COSMIC	13.984	Down-regulation
TK_Src_SRM_Y	P35222	CTNNB1	Q13882	PTK6	Y64	V62G	62	Missense	proximal	-2	no	2.081	2.070	EPSD;PhosphoSitePlus	COSMIC	1.179	Down-regulation
TK_Src_SRM_Y	P35222	CTNNB1	Q13882	PTK6	Y64	Q61R	61	Missense	distal	-3	no	2.081	1.961	EPSD;PhosphoSitePlus	COSMIC	1.179	Down-regulation
TK_Src_SRM_Y	P35222	CTNNB1	Q13882	PTK6	Y64	D58N	58	Missense	distal	-6	no	2.081	2.084	EPSD;PhosphoSitePlus	COSMIC	1.179	Up-regulation
TK_Src_SRM_Y	P35222	CTNNB1	Q13882	PTK6	Y64	V57A	57	Missense	distal	-7	no	2.081	2.128	EPSD;PhosphoSitePlus	COSMIC	1.179	Up-regulation
TK_Src_SRM_Y	P35222	CTNNB1	Q13882	PTK6	Y64	S60C	60	Missense	distal	-4	no	2.081	2.181	EPSD;PhosphoSitePlus	COSMIC	1.179	Up-regulation
TK_Src_SRM_Y	P35222	CTNNB1	Q13882	PTK6	Y64	V57M	57	Missense	distal	-7	no	2.081	2.067	EPSD;PhosphoSitePlus	COSMIC	1.179	Down-regulation
TK_Src_SRM_Y	P35222	CTNNB1	Q13882	PTK6	Y64	G69E	69	Missense	distal	5	no	2.081	1.825	EPSD;PhosphoSitePlus	COSMIC	1.179	Down-regulation
TK_Src_SRM_Y	P35222	CTNNB1	Q13882	PTK6	Y64	Q61L	61	Missense	distal	-3	no	2.081	2.030	EPSD;PhosphoSitePlus	COSMIC	1.179	Down-regulation
TK_Src_SRM_Y	P35222	CTNNB1	Q13882	PTK6	Y64	E67K	67	Missense	distal	3	no	2.081	1.388	EPSD;PhosphoSitePlus	COSMIC	1.179	Down-regulation
TK_Src_SRM_Y	P35222	CTNNB1	Q13882	PTK6	Y64	W66L	66	Missense	proximal	2	no	2.081	1.983	EPSD;PhosphoSitePlus	COSMIC	1.179	Down-regulation
TK_Src_SRM_Y	P35222	CTNNB1	Q13882	PTK6	Y64	E65K	65	Missense	proximal	1	no	2.081	2.047	EPSD;PhosphoSitePlus	COSMIC	1.179	Down-regulation
TK_Src_SRM_Y	P35222	CTNNB1	Q13882	PTK6	Y64	G69A	69	Missense	distal	5	no	2.081	1.815	EPSD;PhosphoSitePlus	COSMIC	1.179	Down-regulation
TK_Src_SRM_Y	P35222	CTNNB1	Q13882	PTK6	Y64	E67N	67	Missense	distal	3	no	2.081	1.386	EPSD;PhosphoSitePlus	COSMIC	1.179	Down-regulation
TK_Src_SRM_Y	P35222	CTNNB1	Q13882	PTK6	Y64	L63M	63	Missense	proximal	-1	no	2.081	2.063	EPSD;PhosphoSitePlus	COSMIC	1.179	Down-regulation
TK_Src_SRM_Y	P35222	CTNNB1	Q13882	PTK6	Y64	T59A	59	Missense	distal	-5	no	2.081	1.996	EPSD;PhosphoSitePlus	COSMIC	1.179	Down-regulation
TK_Src_SRM_Y	P35222	CTNNB1	Q13882	PTK6	Y331	V325I	325	Missense	distal	-6	no	2.092	2.103	EPSD;PhosphoSitePlus	COSMIC	1.179	Up-regulation
TK_Src_SRM_Y	P35222	CTNNB1	Q13882	PTK6	Y331	L336V	336	Missense	distal	5	no	2.092	2.150	EPSD;PhosphoSitePlus	COSMIC	1.179	Up-regulation
TK_Src_SRM_Y	P35222	CTNNB1	Q13882	PTK6	Y331	I327T	327	Missense	distal	-4	no	2.092	2.012	EPSD;PhosphoSitePlus	COSMIC	1.179	Down-regulation
TK_Src_SRM_Y	P35222	CTNNB1	Q13882	PTK6	Y331	I327V	327	Missense	distal	-4	no	2.092	2.045	EPSD;PhosphoSitePlus	COSMIC	1.179	Down-regulation
TK_Src_SRM_Y	P35222	CTNNB1	Q13882	PTK6	Y331	K335R	335	Missense	distal	4	no	2.092	2.116	EPSD;PhosphoSitePlus	COSMIC	1.179	Up-regulation
TK_Src_SRM_Y	P35222	CTNNB1	Q13882	PTK6	Y331	K335Q	335	Missense	distal	4	no	2.092	2.100	EPSD;PhosphoSitePlus	COSMIC	1.179	Up-regulation
TK_Src_SRM_Y	P35222	CTNNB1	Q13882	PTK6	Y331	L337P	337	Missense	distal	6	no	2.092	1.834	EPSD;PhosphoSitePlus	COSMIC	1.179	Down-regulation
TK_Src_SRM_Y	P35222	CTNNB1	Q13882	PTK6	Y331	L324H	324	Missense	distal	-7	no	2.092	2.099	EPSD;PhosphoSitePlus	COSMIC	1.179	Up-regulation
TK_Src_SRM_Y	P35222	CTNNB1	Q13882	PTK6	Y333	L336V	336	Missense	distal	3	no	1.300	1.374	EPSD;PhosphoSitePlus	COSMIC	1.179	Up-regulation
TK_Src_SRM_Y	P35222	CTNNB1	Q13882	PTK6	Y333	I327T	327	Missense	distal	-6	no	1.300	1.213	EPSD;PhosphoSitePlus	COSMIC	1.179	Down-regulation
TK_Src_SRM_Y	P35222	CTNNB1	Q13882	PTK6	Y333	I327V	327	Missense	distal	-6	no	1.300	1.288	EPSD;PhosphoSitePlus	COSMIC	1.179	Down-regulation
TK_Src_SRM_Y	P35222	CTNNB1	Q13882	PTK6	Y333	K335R	335	Missense	proximal	2	no	1.300	1.385	EPSD;PhosphoSitePlus	COSMIC	1.179	Up-regulation
TK_Src_SRM_Y	P35222	CTNNB1	Q13882	PTK6	Y333	K335Q	335	Missense	proximal	2	no	1.300	1.283	EPSD;PhosphoSitePlus	COSMIC	1.179	Down-regulation
TK_Src_SRM_Y	P35222	CTNNB1	Q13882	PTK6	Y333	L337P	337	Missense	distal	4	no	1.300	1.245	EPSD;PhosphoSitePlus	COSMIC	1.179	Down-regulation
TK_Src_SRM_Y	P35222	CTNNB1	Q13882	PTK6	Y724	H720P	720	Missense	distal	-4	no	1.285	1.175	EPSD	COSMIC	1.179	Loss
TK_Src_SRM_Y	P35222	CTNNB1	Q13882	PTK6	Y724	A728T	728	Missense	distal	4	no	1.285	1.299	EPSD	COSMIC	1.179	Up-regulation
TK_Src_SRM_Y	P35222	CTNNB1	Q13882	PTK6	Y724	D727H	727	Missense	distal	3	no	1.285	1.463	EPSD	COSMIC	1.179	Up-regulation
TK_Src_SRM_Y	P35222	CTNNB1	Q13882	PTK6	Y724	R717C	717	Missense	distal	-7	no	1.285	1.274	EPSD	COSMIC	1.179	Down-regulation
TK_Src_SRM_Y	P35222	CTNNB1	Q13882	PTK6	Y724	G730S	730	Missense	distal	6	no	1.285	1.093	EPSD	COSMIC	1.179	Loss
TK_Src_SRM_Y	P35222	CTNNB1	Q13882	PTK6	Y724	Y724S	724	Missense	central	0	yes	1.285	0.000	EPSD	COSMIC	1.179	Loss
TK_Src_SRM_Y	P35222	CTNNB1	Q13882	PTK6	Y724	L729F	729	Missense	distal	5	no	1.285	1.337	EPSD	COSMIC	1.179	Up-regulation
TK_Src_SRM_Y	P35222	CTNNB1	Q13882	PTK6	Y724	G723S	723	Missense	proximal	-1	no	1.285	1.352	EPSD	COSMIC	1.179	Up-regulation
TK_Src_SRM_Y	P35222	CTNNB1	Q13882	PTK6	Y724	D727A	727	Missense	distal	3	no	1.285	1.529	EPSD	COSMIC	1.179	Up-regulation
TK_Src_SRM_Y	P35222	CTNNB1	Q13882	PTK6	Y724	Y724C	724	Missense	central	0	yes	1.285	0.000	EPSD	COSMIC	1.179	Loss
TK_Src_SRM_Y	P35222	CTNNB1	Q13882	PTK6	Y724	G725D	725	Missense	proximal	1	no	1.285	1.324	EPSD	COSMIC	1.179	Up-regulation
TK_Src_SRM_PTK6_Y	P35222	CTNNB1	Q13882	PTK6	Y64	V62G	62	Missense	proximal	-2	no	27.456	27.425	EPSD;PhosphoSitePlus	COSMIC	13.984	Down-regulation
TK_Src_SRM_PTK6_Y	P35222	CTNNB1	Q13882	PTK6	Y64	Q61R	61	Missense	distal	-3	no	27.456	24.433	EPSD;PhosphoSitePlus	COSMIC	13.984	Down-regulation
TK_Src_SRM_PTK6_Y	P35222	CTNNB1	Q13882	PTK6	Y64	D58N	58	Missense	distal	-6	no	27.456	27.182	EPSD;PhosphoSitePlus	COSMIC	13.984	Down-regulation
TK_Src_SRM_PTK6_Y	P35222	CTNNB1	Q13882	PTK6	Y64	V57A	57	Missense	distal	-7	no	27.456	27.867	EPSD;PhosphoSitePlus	COSMIC	13.984	Up-regulation
TK_Src_SRM_PTK6_Y	P35222	CTNNB1	Q13882	PTK6	Y64	S60C	60	Missense	distal	-4	no	27.456	28.923	EPSD;PhosphoSitePlus	COSMIC	13.984	Up-regulation
TK_Src_SRM_PTK6_Y	P35222	CTNNB1	Q13882	PTK6	Y64	V57M	57	Missense	distal	-7	no	27.456	27.549	EPSD;PhosphoSitePlus	COSMIC	13.984	Up-regulation
TK_Src_SRM_PTK6_Y	P35222	CTNNB1	Q13882	PTK6	Y64	G69E	69	Missense	distal	5	no	27.456	26.889	EPSD;PhosphoSitePlus	COSMIC	13.984	Down-regulation
TK_Src_SRM_PTK6_Y	P35222	CTNNB1	Q13882	PTK6	Y64	Q61L	61	Missense	distal	-3	no	27.456	26.015	EPSD;PhosphoSitePlus	COSMIC	13.984	Down-regulation
TK_Src_SRM_PTK6_Y	P35222	CTNNB1	Q13882	PTK6	Y64	E67K	67	Missense	distal	3	no	27.456	17.715	EPSD;PhosphoSitePlus	COSMIC	13.984	Down-regulation
TK_Src_SRM_PTK6_Y	P35222	CTNNB1	Q13882	PTK6	Y64	W66L	66	Missense	proximal	2	no	27.456	25.769	EPSD;PhosphoSitePlus	COSMIC	13.984	Down-regulation
TK_Src_SRM_PTK6_Y	P35222	CTNNB1	Q13882	PTK6	Y64	E65K	65	Missense	proximal	1	no	27.456	27.321	EPSD;PhosphoSitePlus	COSMIC	13.984	Down-regulation
TK_Src_SRM_PTK6_Y	P35222	CTNNB1	Q13882	PTK6	Y64	G69A	69	Missense	distal	5	no	27.456	25.285	EPSD;PhosphoSitePlus	COSMIC	13.984	Down-regulation
TK_Src_SRM_PTK6_Y	P35222	CTNNB1	Q13882	PTK6	Y64	E67N	67	Missense	distal	3	no	27.456	21.859	EPSD;PhosphoSitePlus	COSMIC	13.984	Down-regulation
TK_Src_SRM_PTK6_Y	P35222	CTNNB1	Q13882	PTK6	Y64	L63M	63	Missense	proximal	-1	no	27.456	27.321	EPSD;PhosphoSitePlus	COSMIC	13.984	Down-regulation
TK_Src_SRM_PTK6_Y	P35222	CTNNB1	Q13882	PTK6	Y64	T59A	59	Missense	distal	-5	no	27.456	27.147	EPSD;PhosphoSitePlus	COSMIC	13.984	Down-regulation
TK_Src_SRM_PTK6_Y	P35222	CTNNB1	Q13882	PTK6	Y86	D83N	83	Missense	distal	-3	no	13.879	14.524	EPSD	COSMIC	13.984	Gain
TK_Src_SRM_PTK6_Y	P35222	CTNNB1	Q13882	PTK6	Y86	M88V	88	Missense	proximal	2	no	13.879	14.505	EPSD	COSMIC	13.984	Gain
TK_Src_SRM_PTK6_Y	P35222	CTNNB1	Q13882	PTK6	Y142	D144N	144	Missense	proximal	2	no	16.974	16.030	PhosphoSitePlus;EPSD	COSMIC	13.984	Down-regulation
TK_Src_SRM_PTK6_Y	P35222	CTNNB1	Q13882	PTK6	Y142	E147K	147	Missense	distal	5	no	16.974	15.271	PhosphoSitePlus;EPSD	COSMIC	13.984	Down-regulation
TK_Src_SRM_PTK6_Y	P35222	CTNNB1	Q13882	PTK6	Y142	A149V	149	Missense	distal	7	no	16.974	18.022	PhosphoSitePlus;EPSD	COSMIC	13.984	Up-regulation
TK_Src_SRM_PTK6_Y	P35222	CTNNB1	Q13882	PTK6	Y142	A149T	149	Missense	distal	7	no	16.974	17.272	PhosphoSitePlus;EPSD	COSMIC	13.984	Up-regulation
TK_Src_SRM_PTK6_Y	P35222	CTNNB1	Q13882	PTK6	Y142	I140T	140	Missense	proximal	-2	no	16.974	18.194	PhosphoSitePlus;EPSD	COSMIC	13.984	Up-regulation
TK_Src_SRM_PTK6_Y	P35222	CTNNB1	Q13882	PTK6	Y142	A146T	146	Missense	distal	4	no	16.974	17.026	PhosphoSitePlus;EPSD	COSMIC	13.984	Up-regulation
TK_Src_SRM_PTK6_Y	P35222	CTNNB1	Q13882	PTK6	Y142	A146S	146	Missense	distal	4	no	16.974	16.842	PhosphoSitePlus;EPSD	COSMIC	13.984	Down-regulation
TK_Src_SRM_PTK6_Y	P35222	CTNNB1	Q13882	PTK6	Y331	V325I	325	Missense	distal	-6	no	29.435	29.373	EPSD;PhosphoSitePlus	COSMIC	13.984	Down-regulation
TK_Src_SRM_PTK6_Y	P35222	CTNNB1	Q13882	PTK6	Y331	L336V	336	Missense	distal	5	no	29.435	30.554	EPSD;PhosphoSitePlus	COSMIC	13.984	Up-regulation
TK_Src_SRM_PTK6_Y	P35222	CTNNB1	Q13882	PTK6	Y331	I327T	327	Missense	distal	-4	no	29.435	27.813	EPSD;PhosphoSitePlus	COSMIC	13.984	Down-regulation
TK_Src_SRM_PTK6_Y	P35222	CTNNB1	Q13882	PTK6	Y331	I327V	327	Missense	distal	-4	no	29.435	28.654	EPSD;PhosphoSitePlus	COSMIC	13.984	Down-regulation
TK_Src_SRM_PTK6_Y	P35222	CTNNB1	Q13882	PTK6	Y331	K335R	335	Missense	distal	4	no	29.435	29.673	EPSD;PhosphoSitePlus	COSMIC	13.984	Up-regulation
TK_Src_SRM_PTK6_Y	P35222	CTNNB1	Q13882	PTK6	Y331	K335Q	335	Missense	distal	4	no	29.435	29.386	EPSD;PhosphoSitePlus	COSMIC	13.984	Down-regulation
TK_Src_SRM_PTK6_Y	P35222	CTNNB1	Q13882	PTK6	Y331	L337P	337	Missense	distal	6	no	29.435	27.225	EPSD;PhosphoSitePlus	COSMIC	13.984	Down-regulation
TK_Src_SRM_PTK6_Y	P35222	CTNNB1	Q13882	PTK6	Y331	L324H	324	Missense	distal	-7	no	29.435	29.488	EPSD;PhosphoSitePlus	COSMIC	13.984	Up-regulation
TK_Src_SRM_PTK6_Y	P35222	CTNNB1	Q13882	PTK6	Y333	L336V	336	Missense	distal	3	no	26.739	27.931	EPSD;PhosphoSitePlus	COSMIC	13.984	Up-regulation
TK_Src_SRM_PTK6_Y	P35222	CTNNB1	Q13882	PTK6	Y333	I327T	327	Missense	distal	-6	no	26.739	25.032	EPSD;PhosphoSitePlus	COSMIC	13.984	Down-regulation
TK_Src_SRM_PTK6_Y	P35222	CTNNB1	Q13882	PTK6	Y333	I327V	327	Missense	distal	-6	no	26.739	26.801	EPSD;PhosphoSitePlus	COSMIC	13.984	Up-regulation
TK_Src_SRM_PTK6_Y	P35222	CTNNB1	Q13882	PTK6	Y333	K335R	335	Missense	proximal	2	no	26.739	28.036	EPSD;PhosphoSitePlus	COSMIC	13.984	Up-regulation
TK_Src_SRM_PTK6_Y	P35222	CTNNB1	Q13882	PTK6	Y333	K335Q	335	Missense	proximal	2	no	26.739	25.462	EPSD;PhosphoSitePlus	COSMIC	13.984	Down-regulation
TK_Src_SRM_PTK6_Y	P35222	CTNNB1	Q13882	PTK6	Y333	L337P	337	Missense	distal	4	no	26.739	26.209	EPSD;PhosphoSitePlus	COSMIC	13.984	Down-regulation
TK_Src_SRM_PTK6_Y	P35222	CTNNB1	Q13882	PTK6	Y489	R486H	486	Missense	distal	-3	no	12.954	14.640	EPSD	COSMIC;CCLE	13.984	Gain
TK_Src_SRM_PTK6_Y	P35222	CTNNB1	Q13882	PTK6	Y724	H720P	720	Missense	distal	-4	no	14.615	13.341	EPSD	COSMIC	13.984	Loss
TK_Src_SRM_PTK6_Y	P35222	CTNNB1	Q13882	PTK6	Y724	A728T	728	Missense	distal	4	no	14.615	14.668	EPSD	COSMIC	13.984	Up-regulation
TK_Src_SRM_PTK6_Y	P35222	CTNNB1	Q13882	PTK6	Y724	D727H	727	Missense	distal	3	no	14.615	18.097	EPSD	COSMIC	13.984	Up-regulation
TK_Src_SRM_PTK6_Y	P35222	CTNNB1	Q13882	PTK6	Y724	R717C	717	Missense	distal	-7	no	14.615	14.552	EPSD	COSMIC	13.984	Down-regulation
TK_Src_SRM_PTK6_Y	P35222	CTNNB1	Q13882	PTK6	Y724	G730S	730	Missense	distal	6	no	14.615	13.666	EPSD	COSMIC	13.984	Loss
TK_Src_SRM_PTK6_Y	P35222	CTNNB1	Q13882	PTK6	Y724	Y724S	724	Missense	central	0	yes	14.615	0.000	EPSD	COSMIC	13.984	Loss
TK_Src_SRM_PTK6_Y	P35222	CTNNB1	Q13882	PTK6	Y724	L729F	729	Missense	distal	5	no	14.615	15.737	EPSD	COSMIC	13.984	Up-regulation
TK_Src_SRM_PTK6_Y	P35222	CTNNB1	Q13882	PTK6	Y724	G723S	723	Missense	proximal	-1	no	14.615	15.179	EPSD	COSMIC	13.984	Up-regulation
TK_Src_SRM_PTK6_Y	P35222	CTNNB1	Q13882	PTK6	Y724	D727A	727	Missense	distal	3	no	14.615	15.875	EPSD	COSMIC	13.984	Up-regulation
TK_Src_SRM_PTK6_Y	P35222	CTNNB1	Q13882	PTK6	Y724	Y724C	724	Missense	central	0	yes	14.615	0.000	EPSD	COSMIC	13.984	Loss
TK_Src_SRM_PTK6_Y	P35222	CTNNB1	Q13882	PTK6	Y724	G725D	725	Missense	proximal	1	no	14.615	14.941	EPSD	COSMIC	13.984	Up-regulation
TK_Src_SRM_Y	Q9UGK3	STAP2	Q13882	PTK6	Y250	P243S	243	Missense	distal	-7	no	1.628	1.614	PhosphoSitePlus	COSMIC	1.179	Down-regulation
TK_Src_SRM_PTK6_Y	Q9UGK3	STAP2	Q13882	PTK6	Y250	P243S	243	Missense	distal	-7	no	28.373	28.650	PhosphoSitePlus	COSMIC	13.984	Up-regulation
TK_Src_SRM_Y	P56945	BCAR1	Q13882	PTK6	Y165	P171H	171	Missense	distal	6	no	1.749	1.877	EPSD;PhosphoSitePlus	COSMIC	1.179	Up-regulation
TK_Src_SRM_Y	P56945	BCAR1	Q13882	PTK6	Y165	D163E	163	Missense	proximal	-2	no	1.749	1.779	EPSD;PhosphoSitePlus	COSMIC	1.179	Up-regulation
TK_Src_SRM_Y	P56945	BCAR1	Q13882	PTK6	Y165	P158S	158	Missense	distal	-7	no	1.749	1.734	EPSD;PhosphoSitePlus	COSMIC	1.179	Down-regulation
TK_Src_SRM_Y	P56945	BCAR1	Q13882	PTK6	Y165	G170W	170	Missense	distal	5	no	1.749	1.790	EPSD;PhosphoSitePlus	COSMIC	1.179	Up-regulation
TK_Src_SRM_Y	P56945	BCAR1	Q13882	PTK6	Y165	Q166H	166	Missense	proximal	1	no	1.749	1.718	EPSD;PhosphoSitePlus	COSMIC	1.179	Down-regulation
TK_Src_SRM_Y	P56945	BCAR1	Q13882	PTK6	Y165	P168L	168	Missense	distal	3	no	1.749	0.752	EPSD;PhosphoSitePlus	COSMIC	1.179	Loss
TK_Src_SRM_Y	P56945	BCAR1	Q13882	PTK6	Y165	A161V	161	Missense	distal	-4	no	1.749	1.803	EPSD;PhosphoSitePlus	COSMIC	1.179	Up-regulation
TK_Src_SRM_Y	P56945	BCAR1	Q13882	PTK6	Y165	G172A	172	Missense	distal	7	no	1.749	1.681	EPSD;PhosphoSitePlus	COSMIC	1.179	Down-regulation
TK_Src_SRM_Y	P56945	BCAR1	Q13882	PTK6	Y222	A227G	227	Missense	distal	5	no	1.142	1.407	EPSD	COSMIC	1.179	Gain
TK_Src_SRM_Y	P56945	BCAR1	Q13882	PTK6	Y222	A227V	227	Missense	distal	5	no	1.142	1.389	EPSD	COSMIC	1.179	Gain
TK_Src_SRM_Y	P56945	BCAR1	Q13882	PTK6	Y234	A227G	227	Missense	distal	-7	no	1.255	1.186	EPSD	COSMIC	1.179	Down-regulation
TK_Src_SRM_Y	P56945	BCAR1	Q13882	PTK6	Y234	A227V	227	Missense	distal	-7	no	1.255	1.207	EPSD	COSMIC	1.179	Down-regulation
TK_Src_SRM_Y	P56945	BCAR1	Q13882	PTK6	Y234	P237L	237	Missense	distal	3	no	1.255	0.258	EPSD	COSMIC	1.179	Loss
TK_Src_SRM_Y	P56945	BCAR1	Q13882	PTK6	Y262	Y267N	267	Missense	distal	5	no	2.294	2.165	EPSD	COSMIC	1.179	Down-regulation
TK_Src_SRM_Y	P56945	BCAR1	Q13882	PTK6	Y262	R255W	255	Missense	distal	-7	no	2.294	2.267	EPSD	COSMIC	1.179	Down-regulation
TK_Src_SRM_Y	P56945	BCAR1	Q13882	PTK6	Y262	Q261H	261	Missense	proximal	-1	no	2.294	2.313	EPSD	COSMIC	1.179	Up-regulation
TK_Src_SRM_Y	P56945	BCAR1	Q13882	PTK6	Y267	Y267N	267	Missense	central	0	yes	1.291	0.000	EPSD	COSMIC	1.179	Loss
TK_Src_SRM_Y	P56945	BCAR1	Q13882	PTK6	Y267	M272V	272	Missense	distal	5	no	1.291	1.371	EPSD	COSMIC	1.179	Up-regulation
TK_Src_SRM_Y	P56945	BCAR1	Q13882	PTK6	Y267	Q261H	261	Missense	distal	-6	no	1.291	1.314	EPSD	COSMIC	1.179	Up-regulation
TK_Src_SRM_Y	P56945	BCAR1	Q13882	PTK6	Y267	A273V	273	Missense	distal	6	no	1.291	1.505	EPSD	COSMIC	1.179	Up-regulation
TK_Src_SRM_Y	P56945	BCAR1	Q13882	PTK6	Y267	A273G	273	Missense	distal	6	no	1.291	1.470	EPSD	COSMIC	1.179	Up-regulation
TK_Src_SRM_Y	P56945	BCAR1	Q13882	PTK6	Y372	A368V	368	Missense	distal	-4	no	1.424	1.478	EPSD	COSMIC	1.179	Up-regulation
TK_Src_SRM_Y	P56945	BCAR1	Q13882	PTK6	Y372	P375L	375	Missense	distal	3	no	1.424	0.427	EPSD	COSMIC	1.179	Loss
TK_Src_SRM_Y	P56945	BCAR1	Q13882	PTK6	Y372	P375S	375	Missense	distal	3	no	1.424	0.570	EPSD	COSMIC	1.179	Loss
TK_Src_SRM_Y	P56945	BCAR1	Q13882	PTK6	Y372	D373N	373	Missense	proximal	1	no	1.424	1.426	EPSD	COSMIC	1.179	Up-regulation
TK_Src_SRM_Y	P56945	BCAR1	Q13882	PTK6	Y372	P365L	365	Missense	distal	-7	no	1.424	1.357	EPSD	COSMIC	1.179	Down-regulation
TK_Src_SRM_Y	P56945	BCAR1	Q13882	PTK6	Y372	R379W	379	Missense	distal	7	no	1.424	1.447	EPSD	COSMIC	1.179	Up-regulation
TK_Src_SRM_Y	P56945	BCAR1	Q13882	PTK6	Y664	D663E	663	Missense	proximal	-1	no	1.255	1.298	PhosphoSitePlus;EPSD	COSMIC	1.179	Up-regulation
TK_Src_SRM_Y	P56945	BCAR1	Q13882	PTK6	Y664	Y664C	664	Missense	central	0	yes	1.255	0.000	PhosphoSitePlus;EPSD	COSMIC	1.179	Loss
TK_Src_SRM_Y	P56945	BCAR1	Q13882	PTK6	Y664	E662K	662	Missense	proximal	-2	no	1.255	1.216	PhosphoSitePlus;EPSD	COSMIC	1.179	Down-regulation
TK_Src_SRM_Y	P56945	BCAR1	Q13882	PTK6	Y664	D665E	665	Missense	proximal	1	no	1.255	1.322	PhosphoSitePlus;EPSD	COSMIC	1.179	Up-regulation
TK_Src_SRM_Y	P56945	BCAR1	Q13882	PTK6	Y664	M661I	661	Missense	distal	-3	no	1.255	1.178	PhosphoSitePlus;EPSD	COSMIC	1.179	Loss
TK_Src_SRM_Y	P56945	BCAR1	Q13882	PTK6	Y664	G671R	671	Missense	distal	7	no	1.255	1.272	PhosphoSitePlus;EPSD	COSMIC	1.179	Up-regulation
TK_Src_SRM_Y	P56945	BCAR1	Q13882	PTK6	Y664	Y666C	666	Missense	proximal	2	no	1.255	1.272	PhosphoSitePlus;EPSD	COSMIC	1.179	Up-regulation
TK_Src_SRM_PTK6_Y	P56945	BCAR1	Q13882	PTK6	Y165	P171H	171	Missense	distal	6	no	27.242	28.082	EPSD;PhosphoSitePlus	COSMIC	13.984	Up-regulation
TK_Src_SRM_PTK6_Y	P56945	BCAR1	Q13882	PTK6	Y165	D163E	163	Missense	proximal	-2	no	27.242	27.120	EPSD;PhosphoSitePlus	COSMIC	13.984	Down-regulation
TK_Src_SRM_PTK6_Y	P56945	BCAR1	Q13882	PTK6	Y165	P158S	158	Missense	distal	-7	no	27.242	27.518	EPSD;PhosphoSitePlus	COSMIC	13.984	Up-regulation
TK_Src_SRM_PTK6_Y	P56945	BCAR1	Q13882	PTK6	Y165	G170W	170	Missense	distal	5	no	27.242	29.298	EPSD;PhosphoSitePlus	COSMIC	13.984	Up-regulation
TK_Src_SRM_PTK6_Y	P56945	BCAR1	Q13882	PTK6	Y165	Q166H	166	Missense	proximal	1	no	27.242	26.103	EPSD;PhosphoSitePlus	COSMIC	13.984	Down-regulation
TK_Src_SRM_PTK6_Y	P56945	BCAR1	Q13882	PTK6	Y165	P168L	168	Missense	distal	3	no	27.242	15.114	EPSD;PhosphoSitePlus	COSMIC	13.984	Down-regulation
TK_Src_SRM_PTK6_Y	P56945	BCAR1	Q13882	PTK6	Y165	A161V	161	Missense	distal	-4	no	27.242	27.729	EPSD;PhosphoSitePlus	COSMIC	13.984	Up-regulation
TK_Src_SRM_PTK6_Y	P56945	BCAR1	Q13882	PTK6	Y165	G172A	172	Missense	distal	7	no	27.242	27.117	EPSD;PhosphoSitePlus	COSMIC	13.984	Down-regulation
TK_Src_SRM_PTK6_Y	P56945	BCAR1	Q13882	PTK6	Y179	P174R	174	Missense	distal	-5	no	12.318	16.956	EPSD	COSMIC	13.984	Gain
TK_Src_SRM_PTK6_Y	P56945	BCAR1	Q13882	PTK6	Y179	A185V	185	Missense	distal	6	no	12.318	14.824	EPSD	COSMIC;CCLE	13.984	Gain
TK_Src_SRM_PTK6_Y	P56945	BCAR1	Q13882	PTK6	Y192	G188W	188	Missense	distal	-4	no	17.199	17.597	EPSD	COSMIC	13.984	Up-regulation
TK_Src_SRM_PTK6_Y	P56945	BCAR1	Q13882	PTK6	Y192	A185V	185	Missense	distal	-7	no	17.199	16.788	EPSD	COSMIC;CCLE	13.984	Down-regulation
TK_Src_SRM_PTK6_Y	P56945	BCAR1	Q13882	PTK6	Y192	A185S	185	Missense	distal	-7	no	17.199	17.734	EPSD	COSMIC	13.984	Up-regulation
TK_Src_SRM_PTK6_Y	P56945	BCAR1	Q13882	PTK6	Y192	G186W	186	Missense	distal	-6	no	17.199	17.693	EPSD	COSMIC	13.984	Up-regulation
TK_Src_SRM_PTK6_Y	P56945	BCAR1	Q13882	PTK6	Y234	A227G	227	Missense	distal	-7	no	16.323	15.676	EPSD	COSMIC	13.984	Down-regulation
TK_Src_SRM_PTK6_Y	P56945	BCAR1	Q13882	PTK6	Y234	A227V	227	Missense	distal	-7	no	16.323	15.912	EPSD	COSMIC	13.984	Down-regulation
TK_Src_SRM_PTK6_Y	P56945	BCAR1	Q13882	PTK6	Y234	P237L	237	Missense	distal	3	no	16.323	4.196	EPSD	COSMIC	13.984	Loss
TK_Src_SRM_PTK6_Y	P56945	BCAR1	Q13882	PTK6	Y249	R255W	255	Missense	distal	6	no	13.075	14.903	EPSD	COSMIC;CCLE	13.984	Gain
TK_Src_SRM_PTK6_Y	P56945	BCAR1	Q13882	PTK6	Y262	Y267N	267	Missense	distal	5	no	23.113	20.151	EPSD	COSMIC	13.984	Down-regulation
TK_Src_SRM_PTK6_Y	P56945	BCAR1	Q13882	PTK6	Y262	R255W	255	Missense	distal	-7	no	23.113	22.676	EPSD	COSMIC;CCLE	13.984	Down-regulation
TK_Src_SRM_PTK6_Y	P56945	BCAR1	Q13882	PTK6	Y262	Q261H	261	Missense	proximal	-1	no	23.113	23.204	EPSD	COSMIC	13.984	Up-regulation
TK_Src_SRM_PTK6_Y	P56945	BCAR1	Q13882	PTK6	Y267	Y267N	267	Missense	central	0	yes	16.796	0.000	EPSD	COSMIC	13.984	Loss
TK_Src_SRM_PTK6_Y	P56945	BCAR1	Q13882	PTK6	Y267	M272V	272	Missense	distal	5	no	16.796	19.036	EPSD	COSMIC	13.984	Up-regulation
TK_Src_SRM_PTK6_Y	P56945	BCAR1	Q13882	PTK6	Y267	Q261H	261	Missense	distal	-6	no	16.796	17.789	EPSD	COSMIC	13.984	Up-regulation
TK_Src_SRM_PTK6_Y	P56945	BCAR1	Q13882	PTK6	Y267	A273V	273	Missense	distal	6	no	16.796	19.302	EPSD	COSMIC	13.984	Up-regulation
TK_Src_SRM_PTK6_Y	P56945	BCAR1	Q13882	PTK6	Y267	A273G	273	Missense	distal	6	no	16.796	16.594	EPSD	COSMIC	13.984	Down-regulation
TK_Src_SRM_PTK6_Y	P56945	BCAR1	Q13882	PTK6	Y306	A304T	304	Missense	proximal	-2	no	14.791	14.952	EPSD	COSMIC	13.984	Up-regulation
TK_Src_SRM_PTK6_Y	P56945	BCAR1	Q13882	PTK6	Y306	H303R	303	Missense	distal	-3	no	14.791	13.105	EPSD	COSMIC	13.984	Loss
TK_Src_SRM_PTK6_Y	P56945	BCAR1	Q13882	PTK6	Y306	Y306H	306	Missense	central	0	yes	14.791	0.000	EPSD	COSMIC	13.984	Loss
TK_Src_SRM_PTK6_Y	P56945	BCAR1	Q13882	PTK6	Y327	R323L	323	Missense	distal	-4	no	14.282	13.414	EPSD	COSMIC	13.984	Loss
TK_Src_SRM_PTK6_Y	P56945	BCAR1	Q13882	PTK6	Y362	A368V	368	Missense	distal	6	no	13.254	15.759	EPSD	COSMIC	13.984	Gain
TK_Src_SRM_PTK6_Y	P56945	BCAR1	Q13882	PTK6	Y362	P356L	356	Missense	distal	-6	no	13.254	14.355	EPSD	COSMIC	13.984	Gain
TK_Src_SRM_PTK6_Y	P56945	BCAR1	Q13882	PTK6	Y362	P357L	357	Missense	distal	-5	no	13.254	15.928	EPSD	COSMIC	13.984	Gain
TK_Src_SRM_PTK6_Y	P56945	BCAR1	Q13882	PTK6	Y372	A368V	368	Missense	distal	-4	no	23.100	23.587	EPSD	COSMIC	13.984	Up-regulation
TK_Src_SRM_PTK6_Y	P56945	BCAR1	Q13882	PTK6	Y372	P375L	375	Missense	distal	3	no	23.100	10.972	EPSD	COSMIC	13.984	Loss
TK_Src_SRM_PTK6_Y	P56945	BCAR1	Q13882	PTK6	Y372	P375S	375	Missense	distal	3	no	23.100	10.441	EPSD	COSMIC	13.984	Loss
TK_Src_SRM_PTK6_Y	P56945	BCAR1	Q13882	PTK6	Y372	D373N	373	Missense	proximal	1	no	23.100	23.539	EPSD	COSMIC	13.984	Up-regulation
TK_Src_SRM_PTK6_Y	P56945	BCAR1	Q13882	PTK6	Y372	P365L	365	Missense	distal	-7	no	23.100	22.725	EPSD	COSMIC	13.984	Down-regulation
TK_Src_SRM_PTK6_Y	P56945	BCAR1	Q13882	PTK6	Y372	R379W	379	Missense	distal	7	no	23.100	23.582	EPSD	COSMIC	13.984	Up-regulation
TK_Src_SRM_PTK6_Y	P56945	BCAR1	Q13882	PTK6	Y410	D406N	406	Missense	distal	-4	no	16.970	16.431	EPSD	COSMIC	13.984	Down-regulation
TK_Src_SRM_PTK6_Y	P56945	BCAR1	Q13882	PTK6	Y410	S407T	407	Missense	distal	-3	no	16.970	16.149	EPSD	COSMIC;GDSC;CCLE	13.984	Down-regulation
TK_Src_SRM_PTK6_Y	P56945	BCAR1	Q13882	PTK6	Y664	D663E	663	Missense	proximal	-1	no	26.739	26.887	PhosphoSitePlus;EPSD	COSMIC	13.984	Up-regulation
TK_Src_SRM_PTK6_Y	P56945	BCAR1	Q13882	PTK6	Y664	Y664C	664	Missense	central	0	yes	26.739	0.000	PhosphoSitePlus;EPSD	COSMIC	13.984	Loss
TK_Src_SRM_PTK6_Y	P56945	BCAR1	Q13882	PTK6	Y664	E662K	662	Missense	proximal	-2	no	26.739	26.545	PhosphoSitePlus;EPSD	COSMIC	13.984	Down-regulation
TK_Src_SRM_PTK6_Y	P56945	BCAR1	Q13882	PTK6	Y664	D665E	665	Missense	proximal	1	no	26.739	27.473	PhosphoSitePlus;EPSD	COSMIC	13.984	Up-regulation
TK_Src_SRM_PTK6_Y	P56945	BCAR1	Q13882	PTK6	Y664	M661I	661	Missense	distal	-3	no	26.739	24.443	PhosphoSitePlus;EPSD	COSMIC	13.984	Down-regulation
TK_Src_SRM_PTK6_Y	P56945	BCAR1	Q13882	PTK6	Y664	G671R	671	Missense	distal	7	no	26.739	27.581	PhosphoSitePlus;EPSD	COSMIC	13.984	Up-regulation
TK_Src_SRM_PTK6_Y	P56945	BCAR1	Q13882	PTK6	Y664	Y666C	666	Missense	proximal	2	no	26.739	27.178	PhosphoSitePlus;EPSD	COSMIC	13.984	Up-regulation
TK_Src_SRM_PTK6_Y	P56945	BCAR1	Q13882	PTK6	Y815	H814N	814	Missense	proximal	-1	no	13.560	14.021	EPSD	COSMIC	13.984	Gain
TK_Src_SRM_PTK6_Y	P56945	BCAR1	Q13882	PTK6	Y815	N817I	817	Missense	proximal	2	no	13.560	15.608	EPSD	COSMIC	13.984	Gain
TK_Src_SRM_PTK6_Y	Q96P48	ARAP1	Q13882	PTK6	Y231	D232N	232	Missense	proximal	1	no	16.940	17.380	PhosphoSitePlus	COSMIC	13.984	Up-regulation
TK_Src_SRM_Y	P31749	AKT1	Q13882	PTK6	Y315	E322Q	322	Missense	distal	7	no	2.431	2.464	EPSD;PhosphoSitePlus	COSMIC	1.179	Up-regulation
TK_Src_SRM_Y	P31749	AKT1	Q13882	PTK6	Y315	T312I	312	Missense	distal	-3	no	2.431	2.242	EPSD;PhosphoSitePlus	COSMIC	1.179	Down-regulation
TK_Src_SRM_Y	P31749	AKT1	Q13882	PTK6	Y315	V320L	320	Missense	distal	5	no	2.431	2.373	EPSD;PhosphoSitePlus	COSMIC	1.179	Down-regulation
TK_Src_SRM_Y	P31749	AKT1	Q13882	PTK6	Y326	R328C	328	Missense	proximal	2	no	2.808	2.812	PhosphoSitePlus;EPSD	COSMIC	1.179	Up-regulation
TK_Src_SRM_Y	P31749	AKT1	Q13882	PTK6	Y326	E322Q	322	Missense	distal	-4	no	2.808	2.861	PhosphoSitePlus;EPSD	COSMIC	1.179	Up-regulation
TK_Src_SRM_Y	P31749	AKT1	Q13882	PTK6	Y326	N324S	324	Missense	proximal	-2	no	2.808	2.842	PhosphoSitePlus;EPSD	COSMIC	1.179	Up-regulation
TK_Src_SRM_Y	P31749	AKT1	Q13882	PTK6	Y326	V320L	320	Missense	distal	-6	no	2.808	2.784	PhosphoSitePlus;EPSD	COSMIC	1.179	Down-regulation
TK_Src_SRM_Y	P31749	AKT1	Q13882	PTK6	Y326	D323H	323	Missense	distal	-3	no	2.808	2.729	PhosphoSitePlus;EPSD	COSMIC	1.179	Down-regulation
TK_Src_SRM_Y	P31749	AKT1	Q13882	PTK6	Y437	T435I	435	Missense	proximal	-2	no	1.230	1.163	EPSD	COSMIC	1.179	Loss
TK_Src_SRM_Y	P31749	AKT1	Q13882	PTK6	Y437	T443M	443	Missense	distal	6	no	1.230	1.280	EPSD	COSMIC	1.179	Up-regulation
TK_Src_SRM_Y	P31749	AKT1	Q13882	PTK6	Y437	T430M	430	Missense	distal	-7	no	1.230	1.187	EPSD	COSMIC	1.179	Down-regulation
TK_Src_SRM_PTK6_Y	P31749	AKT1	Q13882	PTK6	Y315	E322Q	322	Missense	distal	7	no	34.424	34.022	EPSD;PhosphoSitePlus	COSMIC	13.984	Down-regulation
TK_Src_SRM_PTK6_Y	P31749	AKT1	Q13882	PTK6	Y315	T312I	312	Missense	distal	-3	no	34.424	30.597	EPSD;PhosphoSitePlus	COSMIC	13.984	Down-regulation
TK_Src_SRM_PTK6_Y	P31749	AKT1	Q13882	PTK6	Y315	V320L	320	Missense	distal	5	no	34.424	33.305	EPSD;PhosphoSitePlus	COSMIC	13.984	Down-regulation
TK_Src_SRM_PTK6_Y	P31749	AKT1	Q13882	PTK6	Y326	R328C	328	Missense	proximal	2	no	29.725	29.542	PhosphoSitePlus;EPSD	COSMIC	13.984	Down-regulation
TK_Src_SRM_PTK6_Y	P31749	AKT1	Q13882	PTK6	Y326	E322Q	322	Missense	distal	-4	no	29.725	29.683	PhosphoSitePlus;EPSD	COSMIC	13.984	Down-regulation
TK_Src_SRM_PTK6_Y	P31749	AKT1	Q13882	PTK6	Y326	N324S	324	Missense	proximal	-2	no	29.725	29.722	PhosphoSitePlus;EPSD	COSMIC	13.984	Down-regulation
TK_Src_SRM_PTK6_Y	P31749	AKT1	Q13882	PTK6	Y326	V320L	320	Missense	distal	-6	no	29.725	29.105	PhosphoSitePlus;EPSD	COSMIC	13.984	Down-regulation
TK_Src_SRM_PTK6_Y	P31749	AKT1	Q13882	PTK6	Y326	D323H	323	Missense	distal	-3	no	29.725	27.877	PhosphoSitePlus;EPSD	COSMIC	13.984	Down-regulation
TK_Src_SRM_Y	P51692	STAT5B	Q13882	PTK6	Y699	I704L	704	Missense	distal	5	no	1.817	1.747	PhosphoSitePlus	COSMIC	1.179	Down-regulation
TK_Src_SRM_Y	P51692	STAT5B	Q13882	PTK6	Y699	Q706L	706	Missense	distal	7	no	1.817	1.841	PhosphoSitePlus	COSMIC	1.179	Up-regulation
TK_Src_SRM_Y	P51692	STAT5B	Q13882	PTK6	Y699	V700M	700	Missense	proximal	1	no	1.817	1.808	PhosphoSitePlus	COSMIC	1.179	Down-regulation
TK_Src_SRM_Y	P51692	STAT5B	Q13882	PTK6	Y699	K705N	705	Missense	distal	6	no	1.817	1.941	PhosphoSitePlus	COSMIC	1.179	Up-regulation
TK_Src_SRM_Y	P51692	STAT5B	Q13882	PTK6	Y699	G698E	698	Missense	proximal	-1	no	1.817	1.903	PhosphoSitePlus	COSMIC	1.179	Up-regulation
TK_Src_SRM_PTK6_Y	P51692	STAT5B	Q13882	PTK6	Y699	I704L	704	Missense	distal	5	no	28.331	27.702	PhosphoSitePlus	COSMIC	13.984	Down-regulation
TK_Src_SRM_PTK6_Y	P51692	STAT5B	Q13882	PTK6	Y699	Q706L	706	Missense	distal	7	no	28.331	28.809	PhosphoSitePlus	COSMIC	13.984	Up-regulation
TK_Src_SRM_PTK6_Y	P51692	STAT5B	Q13882	PTK6	Y699	V700M	700	Missense	proximal	1	no	28.331	28.444	PhosphoSitePlus	COSMIC	13.984	Up-regulation
TK_Src_SRM_PTK6_Y	P51692	STAT5B	Q13882	PTK6	Y699	K705N	705	Missense	distal	6	no	28.331	29.138	PhosphoSitePlus	COSMIC	13.984	Up-regulation
TK_Src_SRM_PTK6_Y	P51692	STAT5B	Q13882	PTK6	Y699	G698E	698	Missense	proximal	-1	no	28.331	28.955	PhosphoSitePlus	COSMIC	13.984	Up-regulation
TK_Src_SRM_PTK6_Y	P51692	STAT5B	Q13882	PTK6	Y699	V696L	696	Missense	distal	-3	no	28.331	28.510	PhosphoSitePlus	COSMIC	13.984	Up-regulation
TK_Src_SRM_Y	P49023	PXN	Q13882	PTK6	Y31	P30L	30	Missense	proximal	-1	no	2.040	1.956	EPSD;PhosphoSitePlus	COSMIC	1.179	Down-regulation
TK_Src_SRM_Y	P49023	PXN	Q13882	PTK6	Y181	G175W	175	Missense	distal	-6	no	1.228	1.253	EPSD	COSMIC	1.179	Up-regulation
TK_Src_SRM_PTK6_Y	P49023	PXN	Q13882	PTK6	Y31	P30L	30	Missense	proximal	-1	no	28.873	28.019	EPSD;PhosphoSitePlus	COSMIC	13.984	Down-regulation
TK_Src_SRM_PTK6_Y	P49023	PXN	Q13882	PTK6	Y118	F120S	120	Missense	proximal	2	no	19.182	16.156	PhosphoSitePlus;EPSD	COSMIC	13.984	Down-regulation
TK_Src_SRM_PTK6_Y	P49023	PXN	Q13882	PTK6	Y181	G175W	175	Missense	distal	-6	no	15.662	16.156	EPSD	COSMIC	13.984	Up-regulation
TK_Src_SRM_Y	Q13017	ARHGAP5	Q13882	PTK6	Y587	N592S	592	Missense	distal	5	no	1.213	1.080	EPSD	COSMIC	1.179	Loss
TK_Src_SRM_Y	Q13017	ARHGAP5	Q13882	PTK6	Y1091	D1084Y	1084	Missense	distal	-7	no	2.071	2.018	EPSD	COSMIC	1.179	Down-regulation
TK_Src_SRM_PTK6_Y	Q13017	ARHGAP5	Q13882	PTK6	Y1091	D1084Y	1084	Missense	distal	-7	no	23.828	23.124	EPSD	COSMIC	13.984	Down-regulation
Other_ULK_ULK_ULK1_ST	Q16543	CDC37	O75385	ULK1	S127	T131I	131	Missense	distal	4	no	30.139	29.520	EPSD	COSMIC	29.179	Down-regulation
Other_ULK_ULK_ULK1_ST	Q16543	CDC37	O75385	ULK1	S127	N130D	130	Missense	distal	3	no	30.139	31.257	EPSD	COSMIC	29.179	Up-regulation
Other_ULK_ULK_ULK1_ST	Q16543	CDC37	O75385	ULK1	S127	V129I	129	Missense	proximal	2	no	30.139	30.860	EPSD	COSMIC	29.179	Up-regulation
Other_ULK_ULK_ULK1_ST	Q16543	CDC37	O75385	ULK1	S127	E134K	134	Missense	distal	7	no	30.139	30.515	EPSD	COSMIC	29.179	Up-regulation
Other_ULK_ULK_ULK1_ST	Q16543	CDC37	O75385	ULK1	T131	E134K	134	Missense	distal	3	no	27.568	30.328	EPSD	COSMIC	29.179	Gain
Other_ULK_ULK_ULK1_ST	Q16543	CDC37	O75385	ULK1	S140	V143M	143	Missense	distal	3	no	34.433	30.418	EPSD	COSMIC	29.179	Down-regulation
Other_ULK_ULK_ULK1_ST	Q16543	CDC37	O75385	ULK1	S140	V143A	143	Missense	distal	3	no	34.433	34.788	EPSD	COSMIC	29.179	Up-regulation
Other_ULK_ULK_ULK1_ST	Q16543	CDC37	O75385	ULK1	S140	E134K	134	Missense	distal	-6	no	34.433	33.587	EPSD	COSMIC	29.179	Down-regulation
Other_ULK_ULK_ULK1_ST	Q16543	CDC37	O75385	ULK1	S339	H332Y	332	Missense	distal	-7	no	35.355	32.665	PhosphoSitePlus	COSMIC	29.179	Down-regulation
Other_ULK_ULK_ULK1_ST	Q16543	CDC37	O75385	ULK1	S339	I337V	337	Missense	proximal	-2	no	35.355	37.325	PhosphoSitePlus	COSMIC	29.179	Up-regulation
Other_ULK_ULK_ULK1_ST	Q8N122	RPTOR	O75385	ULK1	S8	S3Y	3	Missense	distal	-5	no	47.595	43.242	EPSD	COSMIC	29.179	Down-regulation
Other_ULK_ULK_ULK1_ST	Q8N122	RPTOR	O75385	ULK1	S48	M51I	51	Missense	distal	3	no	32.222	36.421	EPSD	COSMIC	29.179	Up-regulation
Other_ULK_ULK_ULK1_ST	Q8N122	RPTOR	O75385	ULK1	S48	R50K	50	Missense	proximal	2	no	32.222	31.666	EPSD	COSMIC	29.179	Down-regulation
Other_ULK_ULK_ULK1_ST	Q8N122	RPTOR	O75385	ULK1	S48	S42C	42	Missense	distal	-6	no	32.222	28.496	EPSD	COSMIC	29.179	Loss
Other_ULK_ULK_ULK1_ST	Q8N122	RPTOR	O75385	ULK1	S48	M55I	55	Missense	distal	7	no	32.222	32.885	EPSD	COSMIC	29.179	Up-regulation
Other_ULK_ULK_ULK1_ST	Q8N122	RPTOR	O75385	ULK1	S738	S738Y	738	Missense	central	0	yes	43.563	0.000	EPSD	COSMIC	29.179	Loss
Other_ULK_ULK_ULK1_ST	Q8N122	RPTOR	O75385	ULK1	S738	T731A	731	Missense	distal	-7	no	43.563	40.959	EPSD	COSMIC	29.179	Down-regulation
Other_ULK_ULK_ULK1_ST	Q8N122	RPTOR	O75385	ULK1	S792	R789H	789	Missense	distal	-3	no	40.283	40.633	EPSD;PhosphoSitePlus	COSMIC;GDSC;CCLE	29.179	Up-regulation
Other_ULK_ULK_ULK1_ST	Q8N122	RPTOR	O75385	ULK1	S792	R788C	788	Missense	distal	-4	no	40.283	35.898	EPSD;PhosphoSitePlus	COSMIC;GDSC;CCLE	29.179	Down-regulation
Other_ULK_ULK_ULK1_ST	Q8N122	RPTOR	O75385	ULK1	S792	L796I	796	Missense	distal	4	no	40.283	40.524	EPSD;PhosphoSitePlus	COSMIC	29.179	Up-regulation
Other_ULK_ULK_ULK1_ST	Q8N122	RPTOR	O75385	ULK1	S792	R788H	788	Missense	distal	-4	no	40.283	41.408	EPSD;PhosphoSitePlus	COSMIC	29.179	Up-regulation
Other_ULK_ULK_ULK1_ST	Q8N122	RPTOR	O75385	ULK1	S792	S798F	798	Missense	distal	6	no	40.283	39.214	EPSD;PhosphoSitePlus	COSMIC	29.179	Down-regulation
Other_ULK_ULK_ULK1_ST	Q8N122	RPTOR	O75385	ULK1	S792	S792F	792	Missense	central	0	yes	40.283	0.000	EPSD;PhosphoSitePlus	COSMIC	29.179	Loss
Other_ULK_ULK_ULK1_ST	Q8N122	RPTOR	O75385	ULK1	S792	A790S	790	Missense	proximal	-2	no	40.283	45.804	EPSD;PhosphoSitePlus	COSMIC	29.179	Up-regulation
Other_ULK_ULK_ULK1_ST	Q8N122	RPTOR	O75385	ULK1	S792	L799H	799	Missense	distal	7	no	40.283	39.963	EPSD;PhosphoSitePlus	COSMIC	29.179	Down-regulation
Other_ULK_ULK_ULK1_ST	Q8N122	RPTOR	O75385	ULK1	S855	P861L	861	Missense	distal	6	no	37.170	37.045	PhosphoSitePlus;EPSD	COSMIC	29.179	Down-regulation
Other_ULK_ULK_ULK1_ST	Q8N122	RPTOR	O75385	ULK1	S855	V850I	850	Missense	distal	-5	no	37.170	38.051	PhosphoSitePlus;EPSD	COSMIC	29.179	Up-regulation
Other_ULK_ULK_ULK1_ST	Q8N122	RPTOR	O75385	ULK1	S855	A862T	862	Missense	distal	7	no	37.170	37.136	PhosphoSitePlus;EPSD	COSMIC	29.179	Down-regulation
Other_ULK_ULK_ULK1_ST	Q8N122	RPTOR	O75385	ULK1	S855	S854A	854	Missense	proximal	-1	no	37.170	36.347	PhosphoSitePlus;EPSD	COSMIC	29.179	Down-regulation
Other_ULK_ULK_ULK1_ST	Q8N122	RPTOR	O75385	ULK1	S859	P861L	861	Missense	proximal	2	no	49.120	49.618	EPSD;PhosphoSitePlus	COSMIC	29.179	Up-regulation
Other_ULK_ULK_ULK1_ST	Q8N122	RPTOR	O75385	ULK1	S859	A862T	862	Missense	distal	3	no	49.120	46.039	EPSD;PhosphoSitePlus	COSMIC	29.179	Down-regulation
Other_ULK_ULK_ULK1_ST	Q8N122	RPTOR	O75385	ULK1	S859	S854A	854	Missense	distal	-5	no	49.120	46.685	EPSD;PhosphoSitePlus	COSMIC	29.179	Down-regulation
Other_ULK_ULK_ULK1_ST	Q8N122	RPTOR	O75385	ULK1	S886	T889A	889	Missense	distal	3	no	28.310	31.390	EPSD	COSMIC	29.179	Gain
Other_ULK_ULK_ULK1_ST	Q8N122	RPTOR	O75385	ULK1	S886	P879S	879	Missense	distal	-7	no	28.310	31.278	EPSD	COSMIC	29.179	Gain
Other_ULK_ULK_ULK1_ST	Q8N122	RPTOR	O75385	ULK1	S886	D891Y	891	Missense	distal	5	no	28.310	29.930	EPSD	COSMIC	29.179	Gain
Other_ULK_ULK_ULK1_ST	Q8N122	RPTOR	O75385	ULK1	T1121	S1116L	1116	Missense	distal	-5	no	38.432	36.622	EPSD	COSMIC;GDSC;CCLE	29.179	Down-regulation
Other_ULK_ULK_ULK1_ST	Q8N122	RPTOR	O75385	ULK1	T1121	T1121M	1121	Missense	central	0	yes	38.432	0.000	EPSD	COSMIC	29.179	Loss
Other_ULK_ULK_ULK1_ST	Q8N122	RPTOR	O75385	ULK1	T1121	G1124A	1124	Missense	distal	3	no	38.432	41.378	EPSD	COSMIC	29.179	Up-regulation
Other_ULK_ULK_ULK1_ST	Q8N122	RPTOR	O75385	ULK1	T1121	D1117Y	1117	Missense	distal	-4	no	38.432	30.691	EPSD	COSMIC	29.179	Down-regulation
Other_ULK_ULK_ULK1_ST	Q8N122	RPTOR	O75385	ULK1	T1121	L1119Q	1119	Missense	proximal	-2	no	38.432	44.361	EPSD	COSMIC	29.179	Up-regulation
Other_ULK_ULK_ULK1_ST	Q8N122	RPTOR	O75385	ULK1	T1121	T1122M	1122	Missense	proximal	1	no	38.432	38.457	EPSD	COSMIC	29.179	Up-regulation
Other_ULK_ULK_ULK1_ST	Q8N122	RPTOR	O75385	ULK1	T1121	G1126R	1126	Missense	distal	5	no	38.432	38.888	EPSD	COSMIC	29.179	Up-regulation
Other_ULK_ULK_ULK1_ST	Q7Z3C6	ATG9A	O75385	ULK1	S14	P20L	20	Missense	distal	6	no	40.041	39.916	EPSD;PhosphoSitePlus	COSMIC;GDSC;CCLE	29.179	Down-regulation
Other_ULK_ULK_ULK1_ST	Q7Z3C6	ATG9A	O75385	ULK1	S650	R653C	653	Missense	distal	3	no	26.075	30.166	EPSD	COSMIC	29.179	Gain
Other_ULK_ULK_ULK1_ST	Q7Z3C6	ATG9A	O75385	ULK1	S670	A668D	668	Missense	proximal	-2	no	27.664	29.225	EPSD	COSMIC	29.179	Gain
Other_ULK_ULK_ULK1_ST	Q7Z3C6	ATG9A	O75385	ULK1	S675	A679V	679	Missense	distal	4	no	43.821	43.145	EPSD	COSMIC	29.179	Down-regulation
Other_ULK_ULK_ULK1_ST	Q7Z3C6	ATG9A	O75385	ULK1	S675	A668D	668	Missense	distal	-7	no	43.821	45.149	EPSD	COSMIC	29.179	Up-regulation
Other_ULK_ULK_ULK1_ST	Q7Z3C6	ATG9A	O75385	ULK1	S675	S670N	670	Missense	distal	-5	no	43.821	41.350	EPSD	COSMIC;GDSC;CCLE	29.179	Down-regulation
Other_ULK_ULK_ULK1_ST	Q7Z3C6	ATG9A	O75385	ULK1	S761	C764F	764	Missense	distal	3	no	39.220	40.639	PhosphoSitePlus;EPSD	COSMIC;GDSC;CCLE	29.179	Up-regulation
Other_ULK_ULK_ULK1_ST	Q7Z3C6	ATG9A	O75385	ULK1	S761	R768W	768	Missense	distal	7	no	39.220	39.795	PhosphoSitePlus;EPSD	COSMIC;GDSC;CCLE	29.179	Up-regulation
Other_ULK_ULK_ULK1_ST	Q7Z3C6	ATG9A	O75385	ULK1	S817	P820H	820	Missense	distal	3	no	35.891	33.000	EPSD	COSMIC	29.179	Down-regulation
Other_ULK_ULK_ULK1_ST	P09467	FBP1	O75385	ULK1	T256	A251T	251	Missense	distal	-5	no	30.963	32.666	EPSD	COSMIC	29.179	Up-regulation
Other_ULK_ULK_ULK1_ST	P08235	NR3C2	O75385	ULK1	S127	Q124L	124	Missense	distal	-3	no	23.903	34.088	EPSD	COSMIC	29.179	Gain
Other_ULK_ULK_ULK1_ST	P08235	NR3C2	O75385	ULK1	S248	S246F	246	Missense	proximal	-2	no	29.999	16.176	EPSD	COSMIC	29.179	Loss
Other_ULK_ULK_ULK1_ST	P08235	NR3C2	O75385	ULK1	S248	S255G	255	Missense	distal	7	no	29.999	30.197	EPSD	COSMIC	29.179	Up-regulation
Other_ULK_ULK_ULK1_ST	P08235	NR3C2	O75385	ULK1	S311	N305K	305	Missense	distal	-6	no	31.527	34.546	EPSD	COSMIC;GDSC;CCLE	29.179	Up-regulation
Other_ULK_ULK_ULK1_ST	P08235	NR3C2	O75385	ULK1	S311	C308Y	308	Missense	distal	-3	no	31.527	19.961	EPSD	COSMIC	29.179	Loss
Other_ULK_ULK_ULK1_ST	P08235	NR3C2	O75385	ULK1	S534	G528S	528	Missense	distal	-6	no	27.202	30.722	EPSD	COSMIC	29.179	Gain
Other_ULK_ULK_ULK1_ST	P08235	NR3C2	O75385	ULK1	S843	Q850H	850	Missense	distal	7	no	48.835	48.399	PhosphoSitePlus	COSMIC	29.179	Down-regulation
Other_ULK_ULK_ULK1_ST	P08235	NR3C2	O75385	ULK1	S843	A844V	844	Missense	proximal	1	no	48.835	48.830	PhosphoSitePlus	COSMIC	29.179	Down-regulation
Other_ULK_ULK_ULK1_ST	P08235	NR3C2	O75385	ULK1	S843	L848I	848	Missense	distal	5	no	48.835	49.559	PhosphoSitePlus	COSMIC	29.179	Up-regulation
Other_ULK_ULK_ULK1_ST	Q8TEV9	SMCR8	O75385	ULK1	S400	C406Y	406	Missense	distal	6	no	42.706	42.497	PhosphoSitePlus;EPSD	COSMIC	29.179	Down-regulation
Other_ULK_ULK_ULK1_ST	Q8TEV9	SMCR8	O75385	ULK1	S400	S401R	401	Missense	proximal	1	no	42.706	42.712	PhosphoSitePlus;EPSD	COSMIC	29.179	Up-regulation
Other_ULK_ULK_ULK1_ST	Q8TEV9	SMCR8	O75385	ULK1	S400	D396N	396	Missense	distal	-4	no	42.706	40.709	PhosphoSitePlus;EPSD	COSMIC	29.179	Down-regulation
Other_ULK_ULK_ULK1_ST	Q8TEV9	SMCR8	O75385	ULK1	S400	S401N	401	Missense	proximal	1	no	42.706	42.692	PhosphoSitePlus;EPSD	COSMIC;GDSC;CCLE	29.179	Down-regulation
Other_ULK_ULK_ULK1_ST	Q8TEV9	SMCR8	O75385	ULK1	S400	P407L	407	Missense	distal	7	no	42.706	42.690	PhosphoSitePlus;EPSD	COSMIC	29.179	Down-regulation
Other_ULK_ULK_ULK1_ST	Q8TEV9	SMCR8	O75385	ULK1	S492	S489I	489	Missense	distal	-3	no	37.994	49.281	EPSD;PhosphoSitePlus	COSMIC	29.179	Up-regulation
Other_ULK_ULK_ULK1_ST	Q8TEV9	SMCR8	O75385	ULK1	S492	S492R	492	Missense	central	0	yes	37.994	0.000	EPSD;PhosphoSitePlus	COSMIC	29.179	Loss
Other_ULK_ULK_ULK1_ST	Q8TEV9	SMCR8	O75385	ULK1	S498	S492R	492	Missense	distal	-6	no	33.080	32.536	EPSD	COSMIC	29.179	Down-regulation
Other_ULK_ULK_ULK1_ST	Q8TEV9	SMCR8	O75385	ULK1	S513	R510M	510	Missense	distal	-3	no	27.601	39.145	EPSD	COSMIC	29.179	Gain
Other_ULK_ULK_ULK1_ST	Q8TEV9	SMCR8	O75385	ULK1	S562	E568K	568	Missense	distal	6	no	43.467	42.685	EPSD;PhosphoSitePlus	COSMIC;GDSC;CCLE	29.179	Down-regulation
Other_ULK_ULK_ULK1_ST	Q8TEV9	SMCR8	O75385	ULK1	S606	A602D	602	Missense	distal	-4	no	32.965	37.524	EPSD	COSMIC	29.179	Up-regulation
Other_ULK_ULK_ULK1_ST	Q8TEV9	SMCR8	O75385	ULK1	S643	A649T	649	Missense	distal	6	no	33.692	33.482	EPSD	COSMIC;GDSC	29.179	Down-regulation
Other_ULK_ULK_ULK1_ST	Q8TEV9	SMCR8	O75385	ULK1	S643	P637L	637	Missense	distal	-6	no	33.692	35.252	EPSD	COSMIC	29.179	Up-regulation
Other_ULK_ULK_ULK1_ST	Q8TEV9	SMCR8	O75385	ULK1	S643	S639F	639	Missense	distal	-4	no	33.692	28.733	EPSD	COSMIC;GDSC;CCLE	29.179	Loss
Other_ULK_ULK_ULK1_ST	Q8TEV9	SMCR8	O75385	ULK1	S643	R640Q	640	Missense	distal	-3	no	33.692	25.876	EPSD	COSMIC	29.179	Loss
Other_ULK_ULK_ULK1_ST	Q15436	SEC23A	O75385	ULK1	S150	S150F	150	Missense	central	0	yes	32.746	0.000	EPSD	COSMIC;GDSC;CCLE	29.179	Loss
Other_ULK_ULK_ULK1_ST	Q15436	SEC23A	O75385	ULK1	S150	E149K	149	Missense	proximal	-1	no	32.746	31.895	EPSD	COSMIC	29.179	Down-regulation
Other_ULK_ULK_ULK1_ST	Q15436	SEC23A	O75385	ULK1	S150	L157V	157	Missense	distal	7	no	32.746	33.119	EPSD	COSMIC	29.179	Up-regulation
Other_ULK_ULK_ULK1_ST	Q15436	SEC23A	O75385	ULK1	S150	E149A	149	Missense	proximal	-1	no	32.746	32.136	EPSD	COSMIC	29.179	Down-regulation
Other_ULK_ULK_ULK1_ST	Q15436	SEC23A	O75385	ULK1	S150	L155F	155	Missense	distal	5	no	32.746	33.665	EPSD	COSMIC	29.179	Up-regulation
Other_ULK_ULK_ULK1_ST	Q15436	SEC23A	O75385	ULK1	S207	L211V	211	Missense	distal	4	no	41.270	40.962	PhosphoSitePlus;EPSD	COSMIC	29.179	Down-regulation
Other_ULK_ULK_ULK1_ST	Q15436	SEC23A	O75385	ULK1	S207	Q213E	213	Missense	distal	6	no	41.270	41.682	PhosphoSitePlus;EPSD	COSMIC	29.179	Up-regulation
Other_ULK_ULK_ULK1_ST	Q15436	SEC23A	O75385	ULK1	S207	E202D	202	Missense	distal	-5	no	41.270	38.799	PhosphoSitePlus;EPSD	COSMIC	29.179	Down-regulation
Other_ULK_ULK_ULK1_ST	Q15436	SEC23A	O75385	ULK1	S207	A214T	214	Missense	distal	7	no	41.270	41.236	PhosphoSitePlus;EPSD	COSMIC	29.179	Down-regulation
Other_ULK_ULK_ULK1_ST	Q15436	SEC23A	O75385	ULK1	S207	M203I	203	Missense	distal	-4	no	41.270	38.618	PhosphoSitePlus;EPSD	COSMIC	29.179	Down-regulation
Other_ULK_ULK_ULK1_ST	Q15436	SEC23A	O75385	ULK1	T405	M400T	400	Missense	distal	-5	no	38.599	36.470	EPSD;PhosphoSitePlus	COSMIC	29.179	Down-regulation
Other_ULK_ULK_ULK1_ST	Q15436	SEC23A	O75385	ULK1	T405	M400K	400	Missense	distal	-5	no	38.599	35.085	EPSD;PhosphoSitePlus	COSMIC	29.179	Down-regulation
Other_ULK_ULK_ULK1_ST	Q15436	SEC23A	O75385	ULK1	T405	T405M	405	Missense	central	0	yes	38.599	0.000	EPSD;PhosphoSitePlus	COSMIC	29.179	Loss
Other_ULK_ULK_ULK1_ST	Q15436	SEC23A	O75385	ULK1	T405	G403C	403	Missense	proximal	-2	no	38.599	30.783	EPSD;PhosphoSitePlus	COSMIC	29.179	Down-regulation
Other_ULK_ULK_ULK1_ST	Q15436	SEC23A	O75385	ULK1	T405	G401E	401	Missense	distal	-4	no	38.599	38.342	EPSD;PhosphoSitePlus	COSMIC	29.179	Down-regulation
Other_ULK_ULK_ULK1_ST	Q15436	SEC23A	O75385	ULK1	S567	T573A	573	Missense	distal	6	no	30.917	31.128	EPSD	COSMIC	29.179	Up-regulation
Other_ULK_ULK_ULK1_ST	Q15436	SEC23A	O75385	ULK1	S588	F593L	593	Missense	distal	5	no	36.833	35.914	EPSD	COSMIC	29.179	Down-regulation
Other_ULK_ULK_ULK1_ST	Q15436	SEC23A	O75385	ULK1	S588	Q591H	591	Missense	distal	3	no	36.833	34.831	EPSD	COSMIC	29.179	Down-regulation
Other_ULK_ULK_ULK1_ST	Q15436	SEC23A	O75385	ULK1	S588	F582L	582	Missense	distal	-6	no	36.833	38.974	EPSD	COSMIC	29.179	Up-regulation
Other_ULK_ULK_ULK1_ST	Q15436	SEC23A	O75385	ULK1	S600	P597L	597	Missense	distal	-3	no	21.503	31.234	EPSD	COSMIC	29.179	Gain
Other_ULK_ULK_ULK1_ST	Q15436	SEC23A	O75385	ULK1	S639	L637P	637	Missense	proximal	-2	no	24.718	29.401	EPSD	COSMIC	29.179	Gain
Other_ULK_ULK_ULK1_ST	Q15436	SEC23A	O75385	ULK1	S640	L637P	637	Missense	distal	-3	no	36.566	26.836	EPSD	COSMIC	29.179	Loss
Other_ULK_ULK_ULK1_ST	Q15436	SEC23A	O75385	ULK1	S640	S641C	641	Missense	proximal	1	no	36.566	36.549	EPSD	COSMIC	29.179	Down-regulation
Other_ULK_ULK_ULK1_ST	O75143	ATG13	O75385	ULK1	S334	P333A	333	Missense	proximal	-1	no	33.683	33.455	EPSD	COSMIC	29.179	Down-regulation
Other_ULK_ULK_ULK1_ST	O75143	ATG13	O75385	ULK1	S334	T332S	332	Missense	proximal	-2	no	33.683	38.799	EPSD	COSMIC	29.179	Up-regulation
Other_ULK_ULK_ULK1_ST	O75143	ATG13	O75385	ULK1	S334	P333S	333	Missense	proximal	-1	no	33.683	34.278	EPSD	COSMIC	29.179	Up-regulation
Other_ULK_ULK_ULK1_ST	O75143	ATG13	O75385	ULK1	S334	T332P	332	Missense	proximal	-2	no	33.683	32.738	EPSD	COSMIC	29.179	Down-regulation
Other_ULK_ULK_ULK1_ST	O75143	ATG13	O75385	ULK1	S355	P362H	362	Missense	distal	7	no	47.502	47.166	PhosphoSitePlus;EPSD	COSMIC	29.179	Down-regulation
Other_ULK_ULK_ULK1_ST	O75143	ATG13	O75385	ULK1	S355	P362L	362	Missense	distal	7	no	47.502	47.486	PhosphoSitePlus;EPSD	COSMIC	29.179	Down-regulation
Other_ULK_ULK_ULK1_ST	O75143	ATG13	O75385	ULK1	S355	T351M	351	Missense	distal	-4	no	47.502	46.865	PhosphoSitePlus;EPSD	COSMIC	29.179	Down-regulation
Other_ULK_ULK_ULK1_ST	O75143	ATG13	O75385	ULK1	S355	P362S	362	Missense	distal	7	no	47.502	47.002	PhosphoSitePlus;EPSD	COSMIC	29.179	Down-regulation
Other_ULK_ULK_ULK1_ST	O75143	ATG13	O75385	ULK1	S355	P362T	362	Missense	distal	7	no	47.502	47.588	PhosphoSitePlus;EPSD	COSMIC	29.179	Up-regulation
Other_ULK_ULK_ULK1_ST	P08237	PFKM	O75385	ULK1	S74	M76I	76	Missense	proximal	2	no	43.681	42.946	PhosphoSitePlus;EPSD	COSMIC	29.179	Down-regulation
Other_ULK_ULK_ULK1_ST	P08237	PFKM	O75385	ULK1	S400	P394T	394	Missense	distal	-6	no	30.003	32.877	EPSD	COSMIC	29.179	Up-regulation
Other_ULK_ULK_ULK1_ST	P08237	PFKM	O75385	ULK1	S400	M406K	406	Missense	distal	6	no	30.003	29.511	EPSD	COSMIC	29.179	Down-regulation
Other_ULK_ULK_ULK1_ST	P08237	PFKM	O75385	ULK1	S477	P474H	474	Missense	distal	-3	no	23.123	30.835	EPSD	COSMIC	29.179	Gain
Other_ULK_ULK_ULK1_ST	P08237	PFKM	O75385	ULK1	S667	R673W	673	Missense	distal	6	no	31.262	30.595	EPSD	COSMIC	29.179	Down-regulation
Other_ULK_ULK_ULK1_ST	P08237	PFKM	O75385	ULK1	S667	R673M	673	Missense	distal	6	no	31.262	31.811	EPSD	COSMIC	29.179	Up-regulation
Other_ULK_ULK_ULK1_ST	P08237	PFKM	O75385	ULK1	S667	G665C	665	Missense	proximal	-2	no	31.262	23.445	EPSD	COSMIC	29.179	Loss
Other_ULK_ULK_ULK1_ST	P08237	PFKM	O75385	ULK1	S667	Q664L	664	Missense	distal	-3	no	31.262	41.447	EPSD	COSMIC	29.179	Up-regulation
Other_ULK_ULK_ULK1_ST	P08237	PFKM	O75385	ULK1	S667	Q663P	663	Missense	distal	-4	no	31.262	30.579	EPSD	COSMIC	29.179	Down-regulation
Other_ULK_ULK_ULK1_ST	P08237	PFKM	O75385	ULK1	S762	A765T	765	Missense	distal	3	no	44.518	41.438	EPSD;PhosphoSitePlus	COSMIC	29.179	Down-regulation
Other_ULK_ULK_ULK1_ST	P08237	PFKM	O75385	ULK1	T771	R772W	772	Missense	proximal	1	no	29.325	29.276	EPSD	COSMIC	29.179	Down-regulation
Other_ULK_ULK_ULK1_ST	P08237	PFKM	O75385	ULK1	T771	T771P	771	Missense	central	0	yes	29.325	0.000	EPSD	COSMIC	29.179	Loss
Other_ULK_ULK_ULK1_ST	P08237	PFKM	O75385	ULK1	T771	G776R	776	Missense	distal	5	no	29.325	29.782	EPSD	COSMIC	29.179	Up-regulation
Other_ULK_ULK_ULK1_ST	P08237	PFKM	O75385	ULK1	T771	A765T	765	Missense	distal	-6	no	29.325	30.091	EPSD	COSMIC	29.179	Up-regulation
Other_ULK_ULK_ULK1_ST	Q9BSB4	ATG101	O75385	ULK1	S11	R4H	4	Missense	distal	-7	no	29.051	30.127	EPSD;PhosphoSitePlus	COSMIC	29.179	Gain
Other_ULK_ULK_ULK1_ST	Q9BSB4	ATG101	O75385	ULK1	S11	E13Q	13	Missense	proximal	2	no	29.051	29.288	EPSD;PhosphoSitePlus	COSMIC	29.179	Gain
Other_ULK_ULK_ULK1_ST	Q9BSB4	ATG101	O75385	ULK1	S11	V17L	17	Missense	distal	6	no	29.051	29.238	EPSD;PhosphoSitePlus	COSMIC	29.179	Gain
Other_ULK_ULK_ULK1_ST	Q9BSB4	ATG101	O75385	ULK1	S203	G201D	201	Missense	proximal	-2	no	31.649	31.736	PhosphoSitePlus;EPSD	COSMIC	29.179	Up-regulation
Other_ULK_ULK_ULK1_ST	Q9BSB4	ATG101	O75385	ULK1	S203	R209C	209	Missense	distal	6	no	31.649	31.247	PhosphoSitePlus;EPSD	COSMIC	29.179	Down-regulation
Other_ULK_ULK_ULK1_ST	Q9BSB4	ATG101	O75385	ULK1	S203	M208T	208	Missense	distal	5	no	31.649	33.053	PhosphoSitePlus;EPSD	COSMIC	29.179	Up-regulation
Other_ULK_ULK_ULK1_ST	Q9BSB4	ATG101	O75385	ULK1	S203	S203P	203	Missense	central	0	yes	31.649	0.000	PhosphoSitePlus;EPSD	COSMIC	29.179	Loss
Other_ULK_ULK_ULK1_ST	Q9BSB4	ATG101	O75385	ULK1	S203	G201C	201	Missense	proximal	-2	no	31.649	23.833	PhosphoSitePlus;EPSD	COSMIC	29.179	Loss
Other_ULK_ULK_ULK1_ST	Q9BSB4	ATG101	O75385	ULK1	S203	S203L	203	Missense	central	0	yes	31.649	0.000	PhosphoSitePlus;EPSD	COSMIC	29.179	Loss
Other_ULK_ULK_ULK1_ST	Q15437	SEC23B	O75385	ULK1	S150	L151P	151	Missense	proximal	1	no	31.701	31.687	EPSD	COSMIC	29.179	Down-regulation
Other_ULK_ULK_ULK1_ST	Q15437	SEC23B	O75385	ULK1	S154	L151P	151	Missense	distal	-3	no	36.350	26.619	EPSD	COSMIC	29.179	Loss
Other_ULK_ULK_ULK1_ST	Q15437	SEC23B	O75385	ULK1	T407	D409Y	409	Missense	proximal	2	no	34.319	32.323	EPSD	COSMIC	29.179	Down-regulation
Other_ULK_ULK_ULK1_ST	Q15437	SEC23B	O75385	ULK1	T407	R414L	414	Missense	distal	7	no	34.319	34.301	EPSD	COSMIC	29.179	Down-regulation
Other_ULK_ULK_ULK1_ST	Q14457	BECN1	O75385	ULK1	S64	E67K	67	Missense	distal	3	no	33.444	36.204	EPSD	COSMIC;GDSC	29.179	Up-regulation
Other_ULK_ULK_ULK1_ST	Q14457	BECN1	O75385	ULK1	S64	E61G	61	Missense	distal	-3	no	33.444	30.868	EPSD	COSMIC	29.179	Down-regulation
Other_ULK_ULK_ULK1_ST	Q14457	BECN1	O75385	ULK1	S234	Q240H	240	Missense	distal	6	no	31.052	31.560	EPSD	COSMIC	29.179	Up-regulation
Other_ULK_ULK_ULK1_ST	Q14457	BECN1	O75385	ULK1	S414	T417N	417	Missense	distal	3	no	29.833	31.335	EPSD	COSMIC	29.179	Up-regulation
Other_ULK_ULK_ULK1_ST	P06733	ENO1	O75385	ULK1	S27	V20G	20	Missense	distal	-7	no	30.265	30.800	EPSD	COSMIC	29.179	Up-regulation
Other_ULK_ULK_ULK1_ST	P06733	ENO1	O75385	ULK1	T100	E101K	101	Missense	proximal	1	no	34.501	34.482	EPSD	COSMIC	29.179	Down-regulation
Other_ULK_ULK_ULK1_ST	P06733	ENO1	O75385	ULK1	S104	E101K	101	Missense	distal	-3	no	32.418	32.452	EPSD	COSMIC	29.179	Up-regulation
Other_ULK_ULK_ULK1_ST	P06733	ENO1	O75385	ULK1	S282	I284M	284	Missense	proximal	2	no	39.464	40.199	EPSD;PhosphoSitePlus	COSMIC	29.179	Up-regulation
Other_ULK_ULK_ULK1_ST	P06733	ENO1	O75385	ULK1	S282	A277V	277	Missense	distal	-5	no	39.464	39.991	EPSD;PhosphoSitePlus	COSMIC	29.179	Up-regulation
Other_ULK_ULK_ULK1_ST	P06733	ENO1	O75385	ULK1	S282	Y287C	287	Missense	distal	5	no	39.464	38.653	EPSD;PhosphoSitePlus	COSMIC	29.179	Down-regulation
Other_ULK_ULK_ULK1_ST	P06733	ENO1	O75385	ULK1	S353	Q355R	355	Missense	proximal	2	no	34.369	34.124	EPSD	COSMIC	29.179	Down-regulation
Other_ULK_ULK_ULK1_ST	Q8NFG4	FLCN	O75385	ULK1	S62	R59C	59	Missense	distal	-3	no	32.991	29.717	EPSD	COSMIC	29.179	Down-regulation
Other_ULK_ULK_ULK1_ST	Q8NFG4	FLCN	O75385	ULK1	S62	R59G	59	Missense	distal	-3	no	32.991	24.093	EPSD	COSMIC	29.179	Loss
Other_ULK_ULK_ULK1_ST	Q8NFG4	FLCN	O75385	ULK1	S62	A64V	64	Missense	proximal	2	no	32.991	32.143	EPSD	COSMIC;GDSC;CCLE	29.179	Down-regulation
Other_ULK_ULK_ULK1_ST	Q8NFG4	FLCN	O75385	ULK1	S62	V69L	69	Missense	distal	7	no	32.991	32.617	EPSD	COSMIC	29.179	Down-regulation
Other_ULK_ULK_ULK1_ST	Q8NFG4	FLCN	O75385	ULK1	S62	A64S	64	Missense	proximal	2	no	32.991	33.904	EPSD	COSMIC	29.179	Up-regulation
Other_ULK_ULK_ULK1_ST	Q8NFG4	FLCN	O75385	ULK1	S62	A64T	64	Missense	proximal	2	no	32.991	33.427	EPSD	COSMIC	29.179	Up-regulation
Other_ULK_ULK_ULK1_ST	Q8NFG4	FLCN	O75385	ULK1	S130	E132K	132	Missense	proximal	2	no	29.874	29.309	EPSD	COSMIC	29.179	Down-regulation
Other_ULK_ULK_ULK1_ST	Q8NFG4	FLCN	O75385	ULK1	S298	E305K	305	Missense	distal	7	no	34.105	34.481	EPSD	COSMIC	29.179	Up-regulation
Other_ULK_ULK_ULK1_ST	Q8NFG4	FLCN	O75385	ULK1	S298	D300G	300	Missense	proximal	2	no	34.105	33.827	EPSD	COSMIC	29.179	Down-regulation
Other_ULK_ULK_ULK1_ST	Q8NFG4	FLCN	O75385	ULK1	S298	S302C	302	Missense	distal	4	no	34.105	32.500	EPSD	COSMIC	29.179	Down-regulation
Other_ULK_ULK_ULK1_ST	Q8NFG4	FLCN	O75385	ULK1	S298	S296T	296	Missense	proximal	-2	no	34.105	28.990	EPSD	COSMIC	29.179	Loss
Other_ULK_ULK_ULK1_ST	Q8NFG4	FLCN	O75385	ULK1	S298	S298N	298	Missense	central	0	yes	34.105	0.000	EPSD	COSMIC	29.179	Loss
Other_ULK_ULK_ULK1_ST	Q8NFG4	FLCN	O75385	ULK1	S298	E295K	295	Missense	distal	-3	no	34.105	34.139	EPSD	COSMIC;GDSC;CCLE	29.179	Up-regulation
Other_ULK_ULK_ULK1_ST	Q8NFG4	FLCN	O75385	ULK1	S333	S330F	330	Missense	distal	-3	no	25.653	33.662	EPSD	COSMIC	29.179	Gain
Other_ULK_ULK_ULK1_ST	Q8NFG4	FLCN	O75385	ULK1	S567	R570C	570	Missense	distal	3	no	26.554	30.645	EPSD	COSMIC	29.179	Gain
Other_ULK_ULK_ULK1_ST	Q8NFG4	FLCN	O75385	ULK1	T568	T568M	568	Missense	central	0	yes	33.544	0.000	EPSD	COSMIC;GDSC;CCLE	29.179	Loss
Other_ULK_ULK_ULK1_ST	Q8NFG4	FLCN	O75385	ULK1	T568	R570C	570	Missense	proximal	2	no	33.544	32.002	EPSD	COSMIC	29.179	Down-regulation
Other_ULK_ULK_ULK1_ST	Q8NFG4	FLCN	O75385	ULK1	S571	T568M	568	Missense	distal	-3	no	24.676	45.823	EPSD	COSMIC;GDSC;CCLE	29.179	Gain
Other_ULK_ULK_ULK1_ST	Q8NFG4	FLCN	O75385	ULK1	T573	R578W	578	Missense	distal	5	no	28.497	30.665	EPSD	COSMIC	29.179	Gain
Other_ULK_ULK_ULK1_ST	Q8NFG4	FLCN	O75385	ULK1	T573	T568M	568	Missense	distal	-5	no	28.497	30.626	EPSD	COSMIC;GDSC;CCLE	29.179	Gain
Other_ULK_ULK_ULK1_ST	Q8NFG4	FLCN	O75385	ULK1	T573	R578Q	578	Missense	distal	5	no	28.497	29.272	EPSD	COSMIC	29.179	Gain
Other_ULK_ULK_ULK1_ST	P19367	HK1	O75385	ULK1	S32	R30Q	30	Missense	proximal	-2	no	31.657	35.326	EPSD	COSMIC	29.179	Up-regulation
Other_ULK_ULK_ULK1_ST	P19367	HK1	O75385	ULK1	S32	S32F	32	Missense	central	0	yes	31.657	0.000	EPSD	COSMIC	29.179	Loss
Other_ULK_ULK_ULK1_ST	P19367	HK1	O75385	ULK1	S32	D33Y	33	Missense	proximal	1	no	31.657	31.630	EPSD	COSMIC	29.179	Down-regulation
Other_ULK_ULK_ULK1_ST	P19367	HK1	O75385	ULK1	S32	D33N	33	Missense	proximal	1	no	31.657	31.659	EPSD	COSMIC	29.179	Up-regulation
Other_ULK_ULK_ULK1_ST	P19367	HK1	O75385	ULK1	S32	R30C	30	Missense	proximal	-2	no	31.657	28.276	EPSD	COSMIC	29.179	Loss
Other_ULK_ULK_ULK1_ST	P19367	HK1	O75385	ULK1	S88	G87E	87	Missense	proximal	-1	no	32.766	32.838	EPSD	COSMIC	29.179	Up-regulation
Other_ULK_ULK_ULK1_ST	P19367	HK1	O75385	ULK1	S88	I92F	92	Missense	distal	4	no	32.766	31.734	EPSD	COSMIC	29.179	Down-regulation
Other_ULK_ULK_ULK1_ST	P19367	HK1	O75385	ULK1	S88	R94Q	94	Missense	distal	6	no	32.766	33.194	EPSD	COSMIC	29.179	Up-regulation
Other_ULK_ULK_ULK1_ST	P19367	HK1	O75385	ULK1	S88	L83V	83	Missense	distal	-5	no	32.766	32.668	EPSD	COSMIC	29.179	Down-regulation
Other_ULK_ULK_ULK1_ST	P19367	HK1	O75385	ULK1	S88	G86E	86	Missense	proximal	-2	no	32.766	30.608	EPSD	COSMIC	29.179	Down-regulation
Other_ULK_ULK_ULK1_ST	P19367	HK1	O75385	ULK1	S124	D128Y	128	Missense	distal	4	no	33.000	31.331	EPSD;PhosphoSitePlus	COSMIC	29.179	Down-regulation
Other_ULK_ULK_ULK1_ST	P19367	HK1	O75385	ULK1	S124	H120D	120	Missense	distal	-4	no	33.000	33.591	EPSD;PhosphoSitePlus	COSMIC	29.179	Up-regulation
Other_ULK_ULK_ULK1_ST	P19367	HK1	O75385	ULK1	S124	H120R	120	Missense	distal	-4	no	33.000	31.875	EPSD;PhosphoSitePlus	COSMIC	29.179	Down-regulation
Other_ULK_ULK_ULK1_ST	P19367	HK1	O75385	ULK1	S178	W171C	171	Missense	distal	-7	no	29.802	30.032	EPSD	COSMIC	29.179	Up-regulation
Other_ULK_ULK_ULK1_ST	P19367	HK1	O75385	ULK1	S178	G179A	179	Missense	proximal	1	no	29.802	29.796	EPSD	COSMIC	29.179	Down-regulation
Other_ULK_ULK_ULK1_ST	P19367	HK1	O75385	ULK1	S178	S178G	178	Missense	central	0	yes	29.802	0.000	EPSD	COSMIC	29.179	Loss
Other_ULK_ULK_ULK1_ST	P19367	HK1	O75385	ULK1	S178	G179R	179	Missense	proximal	1	no	29.802	29.819	EPSD	COSMIC	29.179	Up-regulation
Other_ULK_ULK_ULK1_ST	P19367	HK1	O75385	ULK1	S178	S178C	178	Missense	central	0	yes	29.802	0.000	EPSD	COSMIC	29.179	Loss
Other_ULK_ULK_ULK1_ST	P19367	HK1	O75385	ULK1	S178	D184Y	184	Missense	distal	6	no	29.802	28.524	EPSD	COSMIC	29.179	Loss
Other_ULK_ULK_ULK1_ST	P19367	HK1	O75385	ULK1	S178	A177V	177	Missense	proximal	-1	no	29.802	29.884	EPSD	COSMIC	29.179	Up-regulation
Other_ULK_ULK_ULK1_ST	P19367	HK1	O75385	ULK1	S364	D365N	365	Missense	proximal	1	no	39.839	39.840	PhosphoSitePlus;EPSD	COSMIC	29.179	Up-regulation
Other_ULK_ULK_ULK1_ST	P19367	HK1	O75385	ULK1	S364	R358H	358	Missense	distal	-6	no	39.839	42.561	PhosphoSitePlus;EPSD	COSMIC	29.179	Up-regulation
Other_ULK_ULK_ULK1_ST	P19367	HK1	O75385	ULK1	S364	V361A	361	Missense	distal	-3	no	39.839	32.204	PhosphoSitePlus;EPSD	COSMIC	29.179	Down-regulation
Other_ULK_ULK_ULK1_ST	P19367	HK1	O75385	ULK1	T409	R407Q	407	Missense	proximal	-2	no	30.106	33.775	EPSD	COSMIC	29.179	Up-regulation
Other_ULK_ULK_ULK1_ST	P19367	HK1	O75385	ULK1	T409	G414R	414	Missense	distal	5	no	30.106	30.562	EPSD	COSMIC	29.179	Up-regulation
Other_ULK_ULK_ULK1_ST	P19367	HK1	O75385	ULK1	T409	R405S	405	Missense	distal	-4	no	30.106	29.365	EPSD	COSMIC	29.179	Down-regulation
Other_ULK_ULK_ULK1_ST	P19367	HK1	O75385	ULK1	S445	G452C	452	Missense	distal	7	no	29.083	29.583	EPSD	COSMIC	29.179	Gain
Other_ULK_ULK_ULK1_ST	P19367	HK1	O75385	ULK1	S445	G448C	448	Missense	distal	3	no	29.083	31.857	EPSD	COSMIC	29.179	Gain
Other_ULK_ULK_ULK1_ST	P19367	HK1	O75385	ULK1	S445	R441H	441	Missense	distal	-4	no	29.083	30.208	EPSD	COSMIC	29.179	Gain
Other_ULK_ULK_ULK1_ST	P19367	HK1	O75385	ULK1	S447	G452C	452	Missense	distal	5	no	30.625	32.235	EPSD	COSMIC	29.179	Up-regulation
Other_ULK_ULK_ULK1_ST	P19367	HK1	O75385	ULK1	S447	G448C	448	Missense	proximal	1	no	30.625	30.619	EPSD	COSMIC	29.179	Down-regulation
Other_ULK_ULK_ULK1_ST	P19367	HK1	O75385	ULK1	S447	R441H	441	Missense	distal	-6	no	30.625	33.347	EPSD	COSMIC	29.179	Up-regulation
Other_ULK_ULK_ULK1_ST	P19367	HK1	O75385	ULK1	T503	K501N	501	Missense	proximal	-2	no	25.416	30.939	EPSD	COSMIC	29.179	Gain
Other_ULK_ULK_ULK1_ST	P19367	HK1	O75385	ULK1	S889	N887S	887	Missense	proximal	-2	no	25.253	29.838	EPSD	COSMIC	29.179	Gain
Other_ULK_ULK_ULK1_ST	Q8TDY2	RB1CC1	O75385	ULK1	T61	T66M	66	Missense	distal	5	no	33.797	32.394	EPSD	COSMIC	29.179	Down-regulation
Other_ULK_ULK_ULK1_ST	Q8TDY2	RB1CC1	O75385	ULK1	T61	G65R	65	Missense	distal	4	no	33.797	33.618	EPSD	COSMIC	29.179	Down-regulation
Other_ULK_ULK_ULK1_ST	Q8TDY2	RB1CC1	O75385	ULK1	T61	A55V	55	Missense	distal	-6	no	33.797	31.943	EPSD	COSMIC	29.179	Down-regulation
Other_ULK_ULK_ULK1_ST	Q8TDY2	RB1CC1	O75385	ULK1	T61	C60Y	60	Missense	proximal	-1	no	33.797	33.560	EPSD	COSMIC	29.179	Down-regulation
Other_ULK_ULK_ULK1_ST	Q8TDY2	RB1CC1	O75385	ULK1	S222	L217F	217	Missense	distal	-5	no	40.072	38.341	EPSD	COSMIC;GDSC;CCLE	29.179	Down-regulation
Other_ULK_ULK_ULK1_ST	Q8TDY2	RB1CC1	O75385	ULK1	S222	E225K	225	Missense	distal	3	no	40.072	42.832	EPSD	COSMIC	29.179	Up-regulation
Other_ULK_ULK_ULK1_ST	Q8TDY2	RB1CC1	O75385	ULK1	S222	H226Y	226	Missense	distal	4	no	40.072	37.754	EPSD	COSMIC	29.179	Down-regulation
Other_ULK_ULK_ULK1_ST	Q8TDY2	RB1CC1	O75385	ULK1	S237	L242R	242	Missense	distal	5	no	35.274	34.503	EPSD	COSMIC	29.179	Down-regulation
Other_ULK_ULK_ULK1_ST	Q8TDY2	RB1CC1	O75385	ULK1	T249	E252K	252	Missense	distal	3	no	40.427	43.186	EPSD	COSMIC	29.179	Up-regulation
Other_ULK_ULK_ULK1_ST	Q8TDY2	RB1CC1	O75385	ULK1	T249	L242R	242	Missense	distal	-7	no	40.427	41.755	EPSD	COSMIC	29.179	Up-regulation
Other_ULK_ULK_ULK1_ST	Q8TDY2	RB1CC1	O75385	ULK1	T249	D245H	245	Missense	distal	-4	no	40.427	39.835	EPSD	COSMIC	29.179	Down-regulation
Other_ULK_ULK_ULK1_ST	Q8TDY2	RB1CC1	O75385	ULK1	S266	P259S	259	Missense	distal	-7	no	26.940	29.908	EPSD	COSMIC	29.179	Gain
Other_ULK_ULK_ULK1_ST	Q8TDY2	RB1CC1	O75385	ULK1	S281	T285A	285	Missense	distal	4	no	32.407	31.914	EPSD	COSMIC;GDSC;CCLE	29.179	Down-regulation
Other_ULK_ULK_ULK1_ST	Q8TDY2	RB1CC1	O75385	ULK1	S281	Q288K	288	Missense	distal	7	no	32.407	32.494	EPSD	COSMIC	29.179	Up-regulation
Other_ULK_ULK_ULK1_ST	Q8TDY2	RB1CC1	O75385	ULK1	S281	T285S	285	Missense	distal	4	no	32.407	32.771	EPSD	COSMIC	29.179	Up-regulation
Other_ULK_ULK_ULK1_ST	Q8TDY2	RB1CC1	O75385	ULK1	S836	N835K	835	Missense	proximal	-1	no	40.033	39.744	EPSD	COSMIC	29.179	Down-regulation
Other_ULK_ULK_ULK1_ST	Q8TDY2	RB1CC1	O75385	ULK1	S1284	T1280A	1280	Missense	distal	-4	no	31.374	29.639	EPSD	COSMIC	29.179	Down-regulation
Other_ULK_ULK_ULK1_ST	Q8TDY2	RB1CC1	O75385	ULK1	S1286	T1280A	1280	Missense	distal	-6	no	42.267	41.501	EPSD	COSMIC	29.179	Down-regulation
Other_ULK_ULK_ULK1_ST	Q8TDY2	RB1CC1	O75385	ULK1	S1286	Q1292E	1292	Missense	distal	6	no	42.267	42.678	EPSD	COSMIC	29.179	Up-regulation
Other_ULK_ULK_ULK1_ST	Q8TDY2	RB1CC1	O75385	ULK1	S1323	A1326V	1326	Missense	distal	3	no	32.559	32.204	PhosphoSitePlus;EPSD	COSMIC;CCLE	29.179	Down-regulation
Other_ULK_ULK_ULK1_ST	Q8TDY2	RB1CC1	O75385	ULK1	S1323	S1323Y	1323	Missense	central	0	yes	32.559	0.000	PhosphoSitePlus;EPSD	COSMIC;GDSC;CCLE	29.179	Loss
Other_ULK_ULK_ULK1_ST	Q8TDY2	RB1CC1	O75385	ULK1	S1400	R1393C	1393	Missense	distal	-7	no	36.290	34.022	EPSD	COSMIC	29.179	Down-regulation
Other_ULK_ULK_ULK1_ST	Q8TDY2	RB1CC1	O75385	ULK1	S1400	P1401S	1401	Missense	proximal	1	no	36.290	36.303	EPSD	COSMIC	29.179	Up-regulation
Other_ULK_ULK_ULK1_ST	Q8TDY2	RB1CC1	O75385	ULK1	S1400	V1398I	1398	Missense	proximal	-2	no	36.290	34.320	EPSD	COSMIC	29.179	Down-regulation
Other_ULK_ULK_ULK1_ST	Q8TDY2	RB1CC1	O75385	ULK1	S1441	E1447G	1447	Missense	distal	6	no	30.632	30.662	EPSD	COSMIC	29.179	Up-regulation
Other_ULK_ULK_ULK1_ST	Q8TDY2	RB1CC1	O75385	ULK1	S1441	A1437V	1437	Missense	distal	-4	no	30.632	28.404	EPSD	COSMIC	29.179	Loss
Other_ULK_ULK_ULK1_ST	Q8TDY2	RB1CC1	O75385	ULK1	S1484	Q1483L	1483	Missense	proximal	-1	no	48.604	48.492	EPSD	COSMIC	29.179	Down-regulation
Other_ULK_ULK_ULK1_ST	Q8TDY2	RB1CC1	O75385	ULK1	S1486	Q1483L	1483	Missense	distal	-3	no	21.376	31.561	EPSD	COSMIC	29.179	Gain
Other_ULK_ULK_ULK1_ST	O15027	SEC16A	O75385	ULK1	S153	S153F	153	Missense	central	0	yes	36.992	0.000	EPSD	COSMIC	29.179	Loss
Other_ULK_ULK_ULK1_ST	O15027	SEC16A	O75385	ULK1	S153	A160T	160	Missense	distal	7	no	36.992	36.957	EPSD	COSMIC	29.179	Down-regulation
Other_ULK_ULK_ULK1_ST	O15027	SEC16A	O75385	ULK1	S153	R150W	150	Missense	distal	-3	no	36.992	23.333	EPSD	COSMIC	29.179	Loss
Other_ULK_ULK_ULK1_ST	O15027	SEC16A	O75385	ULK1	S153	E148K	148	Missense	distal	-5	no	36.992	33.938	EPSD	COSMIC	29.179	Down-regulation
Other_ULK_ULK_ULK1_ST	O15027	SEC16A	O75385	ULK1	S153	P151S	151	Missense	proximal	-2	no	36.992	43.052	EPSD	COSMIC	29.179	Up-regulation
Other_ULK_ULK_ULK1_ST	O15027	SEC16A	O75385	ULK1	S153	L159F	159	Missense	distal	6	no	36.992	36.520	EPSD	COSMIC	29.179	Down-regulation
Other_ULK_ULK_ULK1_ST	O15027	SEC16A	O75385	ULK1	S346	G353R	353	Missense	distal	7	no	32.548	32.853	EPSD	COSMIC	29.179	Up-regulation
Other_ULK_ULK_ULK1_ST	O15027	SEC16A	O75385	ULK1	S346	S351N	351	Missense	distal	5	no	32.548	33.850	EPSD	COSMIC	29.179	Up-regulation
Other_ULK_ULK_ULK1_ST	O15027	SEC16A	O75385	ULK1	S358	P361L	361	Missense	distal	3	no	36.543	36.100	EPSD	COSMIC	29.179	Down-regulation
Other_ULK_ULK_ULK1_ST	O15027	SEC16A	O75385	ULK1	S358	L355R	355	Missense	distal	-3	no	36.543	34.173	EPSD	COSMIC;GDSC	29.179	Down-regulation
Other_ULK_ULK_ULK1_ST	O15027	SEC16A	O75385	ULK1	S358	G353R	353	Missense	distal	-5	no	36.543	39.291	EPSD	COSMIC	29.179	Up-regulation
Other_ULK_ULK_ULK1_ST	O15027	SEC16A	O75385	ULK1	S358	R354T	354	Missense	distal	-4	no	36.543	35.434	EPSD	COSMIC	29.179	Down-regulation
Other_ULK_ULK_ULK1_ST	O15027	SEC16A	O75385	ULK1	S358	S351N	351	Missense	distal	-7	no	36.543	35.045	EPSD	COSMIC	29.179	Down-regulation
Other_ULK_ULK_ULK1_ST	O15027	SEC16A	O75385	ULK1	S383	G382D	382	Missense	proximal	-1	no	38.725	37.943	EPSD	COSMIC	29.179	Down-regulation
Other_ULK_ULK_ULK1_ST	O15027	SEC16A	O75385	ULK1	S383	P376L	376	Missense	distal	-7	no	38.725	39.312	EPSD	COSMIC	29.179	Up-regulation
Other_ULK_ULK_ULK1_ST	O15027	SEC16A	O75385	ULK1	S383	F385L	385	Missense	proximal	2	no	38.725	39.590	EPSD	COSMIC	29.179	Up-regulation
Other_ULK_ULK_ULK1_ST	O15027	SEC16A	O75385	ULK1	S383	S383I	383	Missense	central	0	yes	38.725	0.000	EPSD	COSMIC	29.179	Loss
Other_ULK_ULK_ULK1_ST	O15027	SEC16A	O75385	ULK1	S391	G395D	395	Missense	distal	4	no	35.029	35.476	EPSD	COSMIC;GDSC;CCLE	29.179	Up-regulation
Other_ULK_ULK_ULK1_ST	O15027	SEC16A	O75385	ULK1	S391	T397K	397	Missense	distal	6	no	35.029	34.862	EPSD	COSMIC	29.179	Down-regulation
Other_ULK_ULK_ULK1_ST	O15027	SEC16A	O75385	ULK1	S391	V393I	393	Missense	proximal	2	no	35.029	35.750	EPSD	COSMIC	29.179	Up-regulation
Other_ULK_ULK_ULK1_ST	O15027	SEC16A	O75385	ULK1	S391	F385L	385	Missense	distal	-6	no	35.029	37.170	EPSD	COSMIC	29.179	Up-regulation
Other_ULK_ULK_ULK1_ST	O15027	SEC16A	O75385	ULK1	S668	Q663P	663	Missense	distal	-5	no	39.418	35.295	EPSD	COSMIC	29.179	Down-regulation
Other_ULK_ULK_ULK1_ST	O15027	SEC16A	O75385	ULK1	S668	A662D	662	Missense	distal	-6	no	39.418	39.625	EPSD	COSMIC	29.179	Up-regulation
Other_ULK_ULK_ULK1_ST	O15027	SEC16A	O75385	ULK1	S668	S672L	672	Missense	distal	4	no	39.418	38.194	EPSD	COSMIC	29.179	Down-regulation
Other_ULK_ULK_ULK1_ST	O15027	SEC16A	O75385	ULK1	S668	F667L	667	Missense	proximal	-1	no	39.418	40.100	EPSD	COSMIC	29.179	Up-regulation
Other_ULK_ULK_ULK1_ST	O15027	SEC16A	O75385	ULK1	T812	G814R	814	Missense	proximal	2	no	33.649	33.998	EPSD	COSMIC	29.179	Up-regulation
Other_ULK_ULK_ULK1_ST	O15027	SEC16A	O75385	ULK1	T812	T812A	812	Missense	central	0	yes	33.649	0.000	EPSD	COSMIC	29.179	Loss
Other_ULK_ULK_ULK1_ST	O15027	SEC16A	O75385	ULK1	T812	G814E	814	Missense	proximal	2	no	33.649	34.007	EPSD	COSMIC	29.179	Up-regulation
Other_ULK_ULK_ULK1_ST	O15027	SEC16A	O75385	ULK1	T812	T819A	819	Missense	distal	7	no	33.649	33.683	EPSD	COSMIC	29.179	Up-regulation
Other_ULK_ULK_ULK1_ST	O15027	SEC16A	O75385	ULK1	S838	A840D	840	Missense	proximal	2	no	33.448	34.015	EPSD	COSMIC	29.179	Up-regulation
Other_ULK_ULK_ULK1_ST	O15027	SEC16A	O75385	ULK1	S838	S836I	836	Missense	proximal	-2	no	33.448	22.337	EPSD	COSMIC	29.179	Loss
Other_ULK_ULK_ULK1_ST	O15027	SEC16A	O75385	ULK1	S838	N832S	832	Missense	distal	-6	no	33.448	34.722	EPSD	COSMIC	29.179	Up-regulation
Other_ULK_ULK_ULK1_ST	O15027	SEC16A	O75385	ULK1	S1045	S1048N	1048	Missense	distal	3	no	30.862	33.578	EPSD	COSMIC	29.179	Up-regulation
Other_ULK_ULK_ULK1_ST	O15027	SEC16A	O75385	ULK1	S1045	E1039K	1039	Missense	distal	-6	no	30.862	30.016	EPSD	COSMIC;CCLE	29.179	Down-regulation
Other_ULK_ULK_ULK1_ST	O15027	SEC16A	O75385	ULK1	S1045	R1042Q	1042	Missense	distal	-3	no	30.862	23.046	EPSD	COSMIC	29.179	Loss
Other_ULK_ULK_ULK1_ST	O15027	SEC16A	O75385	ULK1	S1045	P1038A	1038	Missense	distal	-7	no	30.862	31.534	EPSD	COSMIC	29.179	Up-regulation
Other_ULK_ULK_ULK1_ST	O15027	SEC16A	O75385	ULK1	S1045	E1052K	1052	Missense	distal	7	no	30.862	31.237	EPSD	COSMIC	29.179	Up-regulation
Other_ULK_ULK_ULK1_ST	O15027	SEC16A	O75385	ULK1	S1100	W1094L	1094	Missense	distal	-6	no	27.176	30.635	EPSD	COSMIC	29.179	Gain
Other_ULK_ULK_ULK1_ST	O15027	SEC16A	O75385	ULK1	S1191	R1189H	1189	Missense	proximal	-2	no	24.387	30.957	EPSD	COSMIC	29.179	Gain
Other_ULK_ULK_ULK1_ST	O15027	SEC16A	O75385	ULK1	S1193	R1189H	1189	Missense	distal	-4	no	35.005	36.130	EPSD	COSMIC	29.179	Up-regulation
Other_ULK_ULK_ULK1_ST	O15027	SEC16A	O75385	ULK1	S1193	S1191C	1191	Missense	proximal	-2	no	35.005	23.140	EPSD	COSMIC	29.179	Loss
Other_ULK_ULK_ULK1_ST	O15027	SEC16A	O75385	ULK1	S1193	H1197N	1197	Missense	distal	4	no	35.005	33.844	EPSD	COSMIC	29.179	Down-regulation
Other_ULK_ULK_ULK1_ST	O15027	SEC16A	O75385	ULK1	S1193	R1188C	1188	Missense	distal	-5	no	35.005	32.357	EPSD	COSMIC	29.179	Down-regulation
Other_ULK_ULK_ULK1_ST	O15027	SEC16A	O75385	ULK1	S1532	D1539Y	1539	Missense	distal	7	no	35.962	36.781	EPSD	COSMIC	29.179	Up-regulation
Other_ULK_ULK_ULK1_ST	O15027	SEC16A	O75385	ULK1	S1532	D1539N	1539	Missense	distal	7	no	35.962	36.306	EPSD	COSMIC	29.179	Up-regulation
Other_ULK_ULK_ULK1_ST	O15027	SEC16A	O75385	ULK1	S1532	L1534F	1534	Missense	proximal	2	no	35.962	35.097	EPSD	COSMIC	29.179	Down-regulation
Other_ULK_ULK_ULK1_ST	O15027	SEC16A	O75385	ULK1	S1532	P1525Q	1525	Missense	distal	-7	no	35.962	38.635	EPSD	COSMIC	29.179	Up-regulation
Other_ULK_ULK_ULK1_ST	O15027	SEC16A	O75385	ULK1	S1532	M1538V	1538	Missense	distal	6	no	35.962	35.309	EPSD	COSMIC	29.179	Down-regulation
Other_ULK_ULK_ULK1_ST	O15027	SEC16A	O75385	ULK1	S1532	N1537Y	1537	Missense	distal	5	no	35.962	37.203	EPSD	COSMIC	29.179	Up-regulation
Other_ULK_ULK_ULK1_ST	O15027	SEC16A	O75385	ULK1	S1532	N1535K	1535	Missense	distal	3	no	35.962	39.012	EPSD	COSMIC	29.179	Up-regulation
Other_ULK_ULK_ULK1_ST	O15027	SEC16A	O75385	ULK1	S1766	S1765L	1765	Missense	proximal	-1	no	33.488	32.726	EPSD	COSMIC	29.179	Down-regulation
Other_ULK_ULK_ULK1_ST	O15027	SEC16A	O75385	ULK1	S1766	P1767L	1767	Missense	proximal	1	no	33.488	33.502	EPSD	COSMIC	29.179	Up-regulation
Other_ULK_ULK_ULK1_ST	O15027	SEC16A	O75385	ULK1	S1766	A1759T	1759	Missense	distal	-7	no	33.488	36.093	EPSD	COSMIC	29.179	Up-regulation
Other_ULK_ULK_ULK1_ST	O15027	SEC16A	O75385	ULK1	S1768	S1765L	1765	Missense	distal	-3	no	24.649	38.458	EPSD	COSMIC	29.179	Gain
Other_ULK_ULK_ULK1_ST	O15027	SEC16A	O75385	ULK1	S1774	Q1777K	1777	Missense	distal	3	no	28.075	31.077	EPSD	COSMIC	29.179	Gain
Other_ULK_ULK_ULK1_ST	O15027	SEC16A	O75385	ULK1	S1859	E1862K	1862	Missense	distal	3	no	27.977	30.736	EPSD	COSMIC	29.179	Gain
Other_ULK_ULK_ULK1_ST	O15027	SEC16A	O75385	ULK1	S1905	E1909K	1909	Missense	distal	4	no	48.132	47.609	EPSD	COSMIC	29.179	Down-regulation
Other_ULK_ULK_ULK1_ST	O15027	SEC16A	O75385	ULK1	S1905	K1911E	1911	Missense	distal	6	no	48.132	48.915	EPSD	COSMIC;GDSC;CCLE	29.179	Up-regulation
Other_ULK_ULK_ULK1_ST	O15027	SEC16A	O75385	ULK1	S1952	N1950S	1950	Missense	proximal	-2	no	25.509	30.094	EPSD	COSMIC	29.179	Gain
Other_ULK_ULK_ULK1_ST	O15027	SEC16A	O75385	ULK1	S2126	S2119N	2119	Missense	distal	-7	no	30.518	29.020	EPSD	COSMIC	29.179	Loss
Other_ULK_ULK_ULK1_ST	O00560	SDCBP	O75385	ULK1	S6	D9A	9	Missense	distal	3	no	29.653	30.114	EPSD;PhosphoSitePlus	COSMIC	29.179	Up-regulation
Other_ULK_ULK_ULK1_ST	O00560	SDCBP	O75385	ULK1	S131	L129P	129	Missense	proximal	-2	no	27.414	32.096	EPSD	COSMIC	29.179	Gain
Other_ULK_ULK_ULK1_ST	O00560	SDCBP	O75385	ULK1	T206	I212M	212	Missense	distal	6	no	33.749	34.081	EPSD	COSMIC	29.179	Up-regulation
Other_ULK_ULK_ULK1_ST	O00560	SDCBP	O75385	ULK1	T206	T200S	200	Missense	distal	-6	no	33.749	33.823	EPSD	COSMIC	29.179	Up-regulation
Other_ULK_ULK_ULK1_ST	O00560	SDCBP	O75385	ULK1	T206	M201K	201	Missense	distal	-5	no	33.749	30.236	EPSD	COSMIC	29.179	Down-regulation
Other_ULK_ULK_ULK1_ST	O00560	SDCBP	O75385	ULK1	S285	K280T	280	Missense	distal	-5	no	42.351	43.737	EPSD	COSMIC;GDSC;CCLE	29.179	Up-regulation
Other_ULK_ULK_ULK1_ST	O00560	SDCBP	O75385	ULK1	S289	P296S	296	Missense	distal	7	no	50.554	50.054	EPSD	COSMIC	29.179	Down-regulation
Other_ULK_ULK_ULK1_ST	O00560	SDCBP	O75385	ULK1	T294	P296S	296	Missense	proximal	2	no	42.852	44.279	EPSD	COSMIC	29.179	Up-regulation
Other_ULK_ULK_ULK1_ST	Q9Y4P1	ATG4B	O75385	ULK1	S44	S44F	44	Missense	central	0	yes	41.346	0.000	EPSD	COSMIC	29.179	Loss
Other_ULK_ULK_ULK1_ST	Q9Y4P1	ATG4B	O75385	ULK1	S44	E41K	41	Missense	distal	-3	no	41.346	41.379	EPSD	COSMIC	29.179	Up-regulation
Other_ULK_ULK_ULK1_ST	Q9Y4P1	ATG4B	O75385	ULK1	S316	D314Y	314	Missense	proximal	-2	no	41.974	33.799	PhosphoSitePlus	COSMIC;GDSC;CCLE	29.179	Down-regulation
Other_ULK_ULK_ULK1_ST	Q9Y4P1	ATG4B	O75385	ULK1	S316	G320V	320	Missense	distal	4	no	41.974	40.985	PhosphoSitePlus	COSMIC	29.179	Down-regulation
Other_ULK_ULK_ULK1_ST	Q9Y4P1	ATG4B	O75385	ULK1	S316	P315R	315	Missense	proximal	-1	no	41.974	42.041	PhosphoSitePlus	COSMIC	29.179	Up-regulation
Other_ULK_ULK_ULK1_ST	Q9Y4P1	ATG4B	O75385	ULK1	S316	S309F	309	Missense	distal	-7	no	41.974	39.052	PhosphoSitePlus	COSMIC	29.179	Down-regulation
Other_ULK_ULK_ULK1_ST	Q8NEB9	PIK3C3	O75385	ULK1	S165	P160F	160	Missense	distal	-5	no	32.357	32.477	EPSD	COSMIC	29.179	Up-regulation
Other_ULK_ULK_ULK1_ST	Q8NEB9	PIK3C3	O75385	ULK1	S165	E169K	169	Missense	distal	4	no	32.357	31.834	EPSD	COSMIC	29.179	Down-regulation
Other_ULK_ULK_ULK1_ST	Q8NEB9	PIK3C3	O75385	ULK1	S165	P160A	160	Missense	distal	-5	no	32.357	33.583	EPSD	COSMIC	29.179	Up-regulation
Other_ULK_ULK_ULK1_ST	Q8NEB9	PIK3C3	O75385	ULK1	S165	S168P	168	Missense	distal	3	no	32.357	36.010	EPSD	COSMIC	29.179	Up-regulation
Other_ULK_ULK_ULK1_ST	Q8NEB9	PIK3C3	O75385	ULK1	S207	I201T	201	Missense	distal	-6	no	47.872	49.730	EPSD	COSMIC	29.179	Up-regulation
Other_ULK_ULK_ULK1_ST	Q8NEB9	PIK3C3	O75385	ULK1	S207	S207I	207	Missense	central	0	yes	47.872	0.000	EPSD	COSMIC	29.179	Loss
Other_ULK_ULK_ULK1_ST	Q8NEB9	PIK3C3	O75385	ULK1	S207	E200K	200	Missense	distal	-7	no	47.872	46.175	EPSD	COSMIC	29.179	Down-regulation
Other_ULK_ULK_ULK1_ST	Q8NEB9	PIK3C3	O75385	ULK1	S207	E200D	200	Missense	distal	-7	no	47.872	47.503	EPSD	COSMIC	29.179	Down-regulation
Other_ULK_ULK_ULK1_ST	Q8NEB9	PIK3C3	O75385	ULK1	S261	E263K	263	Missense	proximal	2	no	29.432	28.867	EPSD	COSMIC	29.179	Loss
Other_ULK_ULK_ULK1_ST	Q8NEB9	PIK3C3	O75385	ULK1	S261	P258S	258	Missense	distal	-3	no	29.432	25.353	EPSD	COSMIC	29.179	Loss
Other_ULK_ULK_ULK1_ST	Q8NEB9	PIK3C3	O75385	ULK1	S268	E263K	263	Missense	distal	-5	no	31.168	28.114	EPSD	COSMIC	29.179	Loss
Other_ULK_ULK_ULK1_ST	Q8NEB9	PIK3C3	O75385	ULK1	S268	R275W	275	Missense	distal	7	no	31.168	31.743	EPSD	COSMIC	29.179	Up-regulation
Other_ULK_ULK_ULK1_ST	Q8NEB9	PIK3C3	O75385	ULK1	S268	R275Q	275	Missense	distal	7	no	31.168	31.266	EPSD	COSMIC	29.179	Up-regulation
Other_ULK_ULK_ULK1_ST	Q8NEB9	PIK3C3	O75385	ULK1	S268	K272E	272	Missense	distal	4	no	31.168	31.691	EPSD	COSMIC	29.179	Up-regulation
Other_ULK_ULK_ULK1_ST	Q8NEB9	PIK3C3	O75385	ULK1	S268	K272T	272	Missense	distal	4	no	31.168	31.882	EPSD	COSMIC	29.179	Up-regulation
Other_ULK_ULK_ULK1_ST	Q8NEB9	PIK3C3	O75385	ULK1	S276	K272E	272	Missense	distal	-4	no	27.595	30.907	EPSD	COSMIC	29.179	Gain
Other_ULK_ULK_ULK1_ST	Q8NEB9	PIK3C3	O75385	ULK1	S276	K272T	272	Missense	distal	-4	no	27.595	30.874	EPSD	COSMIC	29.179	Gain
Other_ULK_ULK_ULK1_ST	Q8NEB9	PIK3C3	O75385	ULK1	S454	T447S	447	Missense	distal	-7	no	34.537	34.228	EPSD	COSMIC	29.179	Down-regulation
Other_ULK_ULK_ULK1_ST	Q8NEB9	PIK3C3	O75385	ULK1	S454	S455L	455	Missense	proximal	1	no	34.537	34.539	EPSD	COSMIC	29.179	Up-regulation
Other_ULK_ULK_ULK1_ST	Q8NEB9	PIK3C3	O75385	ULK1	S460	S455L	455	Missense	distal	-5	no	31.859	30.049	EPSD	COSMIC	29.179	Down-regulation
Other_ULK_ULK_ULK1_ST	Q8NEB9	PIK3C3	O75385	ULK1	T513	D510H	510	Missense	distal	-3	no	22.804	29.399	EPSD	COSMIC	29.179	Gain
Other_ULK_ULK_ULK1_ST	Q8NEB9	PIK3C3	O75385	ULK1	T790	G789S	789	Missense	proximal	-1	no	42.354	42.639	EPSD	COSMIC	29.179	Up-regulation
Other_ULK_ULK_ULK1_ST	Q8NEB9	PIK3C3	O75385	ULK1	T790	G788W	788	Missense	proximal	-2	no	42.354	33.751	EPSD	COSMIC	29.179	Down-regulation
Other_ULK_ULK_ULK1_ST	Q8NEB9	PIK3C3	O75385	ULK1	T790	M787T	787	Missense	distal	-3	no	42.354	21.206	EPSD	COSMIC	29.179	Loss
Other_ULK_ULK_ULK1_ST	Q8NEB9	PIK3C3	O75385	ULK1	T790	S792C	792	Missense	proximal	2	no	42.354	40.537	EPSD	COSMIC	29.179	Down-regulation
Other_ULK_ULK_ULK1_ST	Q8NEB9	PIK3C3	O75385	ULK1	T790	G789W	789	Missense	proximal	-1	no	42.354	41.277	EPSD	COSMIC	29.179	Down-regulation
Other_ULK_ULK_ULK1_ST	A2RUS2	DENND3	O75385	ULK1	S445	R448T	448	Missense	distal	3	no	30.698	31.881	EPSD	COSMIC	29.179	Up-regulation
Other_ULK_ULK_ULK1_ST	A2RUS2	DENND3	O75385	ULK1	S445	P446A	446	Missense	proximal	1	no	30.698	30.694	EPSD	COSMIC	29.179	Down-regulation
Other_ULK_ULK_ULK1_ST	A2RUS2	DENND3	O75385	ULK1	S445	R448K	448	Missense	distal	3	no	30.698	36.432	EPSD	COSMIC	29.179	Up-regulation
Other_ULK_ULK_ULK1_ST	A2RUS2	DENND3	O75385	ULK1	S445	R438K	438	Missense	distal	-7	no	30.698	29.456	EPSD	COSMIC	29.179	Down-regulation
Other_ULK_ULK_ULK1_ST	A2RUS2	DENND3	O75385	ULK1	S445	S445N	445	Missense	central	0	yes	30.698	0.000	EPSD	COSMIC	29.179	Loss
Other_ULK_ULK_ULK1_ST	A2RUS2	DENND3	O75385	ULK1	S445	P449R	449	Missense	distal	4	no	30.698	31.077	EPSD	COSMIC	29.179	Up-regulation
Other_ULK_ULK_ULK1_ST	A2RUS2	DENND3	O75385	ULK1	S445	L443P	443	Missense	proximal	-2	no	30.698	35.381	EPSD	COSMIC	29.179	Up-regulation
Other_ULK_ULK_ULK1_ST	A2RUS2	DENND3	O75385	ULK1	S460	K458T	458	Missense	proximal	-2	no	30.033	35.025	EPSD	COSMIC	29.179	Up-regulation
Other_ULK_ULK_ULK1_ST	A2RUS2	DENND3	O75385	ULK1	S460	R457Q	457	Missense	distal	-3	no	30.033	22.217	EPSD	COSMIC	29.179	Loss
Other_ULK_ULK_ULK1_ST	A2RUS2	DENND3	O75385	ULK1	S460	H466Q	466	Missense	distal	6	no	30.033	29.525	EPSD	COSMIC	29.179	Down-regulation
Other_ULK_ULK_ULK1_ST	A2RUS2	DENND3	O75385	ULK1	S460	S459P	459	Missense	proximal	-1	no	30.033	29.438	EPSD	COSMIC	29.179	Down-regulation
Other_ULK_ULK_ULK1_ST	A2RUS2	DENND3	O75385	ULK1	S472	H466Q	466	Missense	distal	-6	no	38.985	37.674	PhosphoSitePlus;EPSD	COSMIC	29.179	Down-regulation
Other_ULK_ULK_ULK1_ST	A2RUS2	DENND3	O75385	ULK1	S490	S490N	490	Missense	central	0	yes	36.893	0.000	EPSD;PhosphoSitePlus	COSMIC	29.179	Loss
Other_ULK_ULK_ULK1_ST	A2RUS2	DENND3	O75385	ULK1	S490	R492W	492	Missense	proximal	2	no	36.893	34.781	EPSD;PhosphoSitePlus	COSMIC	29.179	Down-regulation
Other_ULK_ULK_ULK1_ST	A2RUS2	DENND3	O75385	ULK1	S490	L491P	491	Missense	proximal	1	no	36.893	36.879	EPSD;PhosphoSitePlus	COSMIC	29.179	Down-regulation
Other_ULK_ULK_ULK1_ST	A2RUS2	DENND3	O75385	ULK1	T494	S490N	490	Missense	distal	-4	no	32.472	32.932	EPSD	COSMIC	29.179	Up-regulation
Other_ULK_ULK_ULK1_ST	A2RUS2	DENND3	O75385	ULK1	T494	R492W	492	Missense	proximal	-2	no	32.472	28.305	EPSD	COSMIC	29.179	Loss
Other_ULK_ULK_ULK1_ST	A2RUS2	DENND3	O75385	ULK1	T494	L491P	491	Missense	distal	-3	no	32.472	22.742	EPSD	COSMIC	29.179	Loss
Other_ULK_ULK_ULK1_ST	A2RUS2	DENND3	O75385	ULK1	T494	R500K	500	Missense	distal	6	no	32.472	32.530	EPSD	COSMIC	29.179	Up-regulation
Other_ULK_ULK_ULK1_ST	A2RUS2	DENND3	O75385	ULK1	S1175	C1174R	1174	Missense	proximal	-1	no	29.960	30.529	EPSD	COSMIC	29.179	Up-regulation
Other_ULK_ULK_ULK1_ST	A2RUS2	DENND3	O75385	ULK1	S1175	C1174F	1174	Missense	proximal	-1	no	29.960	29.613	EPSD	COSMIC	29.179	Down-regulation
Other_ULK_ULK_ULK1_ST	Q9C0C7	AMBRA1	O75385	ULK1	S417	P412H	412	Missense	distal	-5	no	26.087	30.526	EPSD	COSMIC	29.179	Gain
Other_ULK_ULK_ULK1_ST	Q9C0C7	AMBRA1	O75385	ULK1	S635	P640S	640	Missense	distal	5	no	46.392	44.812	PhosphoSitePlus;EPSD	COSMIC	29.179	Down-regulation
Other_ULK_ULK_ULK1_ST	Q9C0C7	AMBRA1	O75385	ULK1	S635	P640L	640	Missense	distal	5	no	46.392	46.161	PhosphoSitePlus;EPSD	COSMIC	29.179	Down-regulation
Other_ULK_ULK_ULK1_ST	Q9C0C7	AMBRA1	O75385	ULK1	S635	E642K	642	Missense	distal	7	no	46.392	46.767	PhosphoSitePlus;EPSD	COSMIC	29.179	Up-regulation
Other_ULK_ULK_ULK1_ST	Q9C0C7	AMBRA1	O75385	ULK1	S637	P640S	640	Missense	distal	3	no	30.996	27.343	EPSD	COSMIC	29.179	Loss
Other_ULK_ULK_ULK1_ST	Q9C0C7	AMBRA1	O75385	ULK1	S637	P640L	640	Missense	distal	3	no	30.996	30.553	EPSD	COSMIC	29.179	Down-regulation
Other_ULK_ULK_ULK1_ST	Q9C0C7	AMBRA1	O75385	ULK1	S637	R644M	644	Missense	distal	7	no	30.996	30.692	EPSD	COSMIC	29.179	Down-regulation
Other_ULK_ULK_ULK1_ST	Q9C0C7	AMBRA1	O75385	ULK1	S637	E642K	642	Missense	distal	5	no	30.996	31.905	EPSD	COSMIC	29.179	Up-regulation
Other_ULK_ULK_ULK1_ST	Q9C0C7	AMBRA1	O75385	ULK1	S786	G783D	783	Missense	distal	-3	no	28.286	30.940	EPSD	COSMIC	29.179	Gain
Other_ULK_ULK_ULK1_ST	Q9C0C7	AMBRA1	O75385	ULK1	S1072	S1072N	1072	Missense	central	0	yes	29.853	0.000	EPSD	COSMIC	29.179	Loss
Other_ULK_ULK_ULK1_ST	Q9C0C7	AMBRA1	O75385	ULK1	S1072	R1068W	1068	Missense	distal	-4	no	29.853	24.719	EPSD	COSMIC;CCLE	29.179	Loss
Other_ULK_ULK_ULK1_ST	Q9C0C7	AMBRA1	O75385	ULK1	S1192	S1192F	1192	Missense	central	0	yes	29.841	0.000	EPSD	COSMIC	29.179	Loss
Other_ULK_ULK_ULK1_ST	Q9C0C7	AMBRA1	O75385	ULK1	S1192	S1191F	1191	Missense	proximal	-1	no	29.841	28.397	EPSD	COSMIC	29.179	Loss
Other_ULK_ULK_ULK1_ST	Q9C0C7	AMBRA1	O75385	ULK1	S1192	Q1193E	1193	Missense	proximal	1	no	29.841	29.833	EPSD	COSMIC	29.179	Down-regulation
Other_ULK_ULK_ULK1_ST	Q9C0C7	AMBRA1	O75385	ULK1	S1192	T1194M	1194	Missense	proximal	2	no	29.841	30.012	EPSD	COSMIC	29.179	Up-regulation
Other_ULK_ULK_ULK1_ST	Q9C0C7	AMBRA1	O75385	ULK1	S1192	R1187H	1187	Missense	distal	-5	no	29.841	32.287	EPSD	COSMIC	29.179	Up-regulation
Other_ULK_ULK_ULK1_ST	Q9C0C7	AMBRA1	O75385	ULK1	S1192	S1185N	1185	Missense	distal	-7	no	29.841	28.343	EPSD	COSMIC	29.179	Loss
Other_ULK_ULK_ULK1_ST	Q9C0C7	AMBRA1	O75385	ULK1	T1194	S1191F	1191	Missense	distal	-3	no	22.750	30.759	EPSD	COSMIC	29.179	Gain
Other_ULK_ULK_ULK1_ST	Q9C0C7	AMBRA1	O75385	ULK1	T1203	T1203N	1203	Missense	central	0	yes	30.755	0.000	EPSD	COSMIC	29.179	Loss
Other_ULK_ULK_ULK1_ST	Q9C0C7	AMBRA1	O75385	ULK1	T1203	S1204F	1204	Missense	proximal	1	no	30.755	30.726	EPSD	COSMIC	29.179	Down-regulation
Other_ULK_ULK_ULK1_ST	Q9C0C7	AMBRA1	O75385	ULK1	T1203	Q1207R	1207	Missense	distal	4	no	30.755	30.852	EPSD	COSMIC	29.179	Up-regulation
Other_ULK_ULK_ULK1_ST	Q9C0C7	AMBRA1	O75385	ULK1	T1203	A1200S	1200	Missense	distal	-3	no	30.755	30.115	EPSD	COSMIC;CCLE	29.179	Down-regulation
Other_ULK_ULK_ULK1_ST	Q9C0C7	AMBRA1	O75385	ULK1	S1209	R1212W	1212	Missense	distal	3	no	25.279	31.245	EPSD	COSMIC	29.179	Gain
Other_ULK_ULK_ULK1_ST	Q13045	FLII	O75385	ULK1	S64	S64N	64	Missense	central	0	yes	32.418	0.000	PhosphoSitePlus	COSMIC	29.179	Loss
Other_ULK_ULK_ULK1_ST	Q13045	FLII	O75385	ULK1	S406	A403P	403	Missense	distal	-3	no	26.112	29.550	EPSD	COSMIC	29.179	Gain
Other_ULK_ULK_ULK1_ST	Q13045	FLII	O75385	ULK1	S436	R433C	433	Missense	distal	-3	no	34.426	31.152	EPSD	COSMIC	29.179	Down-regulation
Other_ULK_ULK_ULK1_ST	Q13045	FLII	O75385	ULK1	S436	R429L	429	Missense	distal	-7	no	34.426	33.097	EPSD	COSMIC	29.179	Down-regulation
Other_ULK_ULK_ULK1_ST	Q13045	FLII	O75385	ULK1	S436	D440E	440	Missense	distal	4	no	34.426	33.966	EPSD	COSMIC	29.179	Down-regulation
Other_ULK_ULK_ULK1_ST	Q13045	FLII	O75385	ULK1	S436	R432C	432	Missense	distal	-4	no	34.426	30.041	EPSD	COSMIC	29.179	Down-regulation
Other_ULK_ULK_ULK1_ST	Q13045	FLII	O75385	ULK1	S436	D439E	439	Missense	distal	3	no	34.426	33.598	EPSD	COSMIC	29.179	Down-regulation
Other_ULK_ULK_ULK1_ST	Q13045	FLII	O75385	ULK1	S488	S488F	488	Missense	central	0	yes	41.275	0.000	EPSD	COSMIC	29.179	Loss
Other_ULK_ULK_ULK1_ST	Q13045	FLII	O75385	ULK1	S822	R815H	815	Missense	distal	-7	no	39.142	40.218	EPSD	COSMIC	29.179	Up-regulation
Other_ULK_ULK_ULK1_ST	Q13045	FLII	O75385	ULK1	S822	R815C	815	Missense	distal	-7	no	39.142	36.874	EPSD	COSMIC;CCLE	29.179	Down-regulation
Other_ULK_ULK_ULK1_ST	Q13045	FLII	O75385	ULK1	T847	D840E	840	Missense	distal	-7	no	31.621	31.990	EPSD	COSMIC;GDSC;CCLE	29.179	Up-regulation
Other_ULK_ULK_ULK1_ST	Q13045	FLII	O75385	ULK1	T847	A852V	852	Missense	distal	5	no	31.621	31.542	EPSD	COSMIC	29.179	Down-regulation
Other_ULK_ULK_ULK1_ST	Q13045	FLII	O75385	ULK1	S860	R865C	865	Missense	distal	5	no	33.650	34.804	EPSD	COSMIC	29.179	Up-regulation
CMGC_MAPK_JNK_MAPK9_ST	O95140	MFN2	P45984-2	MAPK9	T653	T654P	654	Missense	proximal	1	no	126.086	145.281	EPSD	COSMIC;GDSC;CCLE	140.458	Gain
CMGC_MAPK_JNK_MAPK9_ST	P40763	STAT3	P45984-2	MAPK9	T118	R114C	114	Missense	distal	-4	no	142.719	141.747	EPSD	COSMIC	140.458	Down-regulation
CMGC_MAPK_JNK_MAPK9_ST	P40763	STAT3	P45984-2	MAPK9	T118	A122V	122	Missense	distal	4	no	142.719	142.943	EPSD	COSMIC	140.458	Up-regulation
CMGC_MAPK_JNK_MAPK9_ST	P40763	STAT3	P45984-2	MAPK9	T133	G126E	126	Missense	distal	-7	no	140.071	141.339	EPSD	COSMIC	140.458	Gain
CMGC_MAPK_JNK_MAPK9_ST	P40763	STAT3	P45984-2	MAPK9	T236	D242Y	242	Missense	distal	6	no	142.300	141.981	EPSD	COSMIC	140.458	Down-regulation
CMGC_MAPK_JNK_MAPK9_ST	P40763	STAT3	P45984-2	MAPK9	T236	E238V	238	Missense	proximal	2	no	142.300	142.431	EPSD	COSMIC	140.458	Up-regulation
CMGC_MAPK_JNK_MAPK9_ST	P40763	STAT3	P45984-2	MAPK9	T236	T236M	236	Missense	central	0	yes	142.300	0.000	EPSD	COSMIC	140.458	Loss
CMGC_MAPK_JNK_MAPK9_ST	P40763	STAT3	P45984-2	MAPK9	T412	L413P	413	Missense	proximal	1	no	106.525	151.427	EPSD	COSMIC	140.458	Gain
CMGC_MAPK_JNK_MAPK9_ST	P40763	STAT3	P45984-2	MAPK9	T433	L430Q	430	Missense	distal	-3	no	139.733	140.763	EPSD	COSMIC	140.458	Gain
CMGC_MAPK_JNK_MAPK9_ST	P40763	STAT3	P45984-2	MAPK9	S701	D698N	698	Missense	distal	-3	no	144.745	145.997	EPSD	COSMIC	140.458	Up-regulation
CMGC_MAPK_JNK_MAPK9_ST	P40763	STAT3	P45984-2	MAPK9	S701	G700R	700	Missense	proximal	-1	no	144.745	144.943	EPSD	COSMIC	140.458	Up-regulation
CMGC_MAPK_JNK_MAPK9_ST	P40763	STAT3	P45984-2	MAPK9	T714	I711L	711	Missense	distal	-3	no	149.040	149.895	EPSD	COSMIC	140.458	Up-regulation
CMGC_MAPK_JNK_MAPK9_ST	P40763	STAT3	P45984-2	MAPK9	S727	D723N	723	Missense	distal	-4	no	156.513	158.534	PhosphoSitePlus	COSMIC	140.458	Up-regulation
TK_Tec_TEC_Y	Q06187	BTK	P42680	TEC	Y223	L222F	222	Missense	proximal	-1	no	353.276	355.235	PhosphoSitePlus	COSMIC	232.776	Up-regulation
TK_Tec_TEC_Y	Q06187	BTK	P42680	TEC	Y223	D224N	224	Missense	proximal	1	no	353.276	352.611	PhosphoSitePlus	COSMIC	232.776	Down-regulation
TK_Tec_TEC_Y	Q06187	BTK	P42680	TEC	Y223	K217R	217	Missense	distal	-6	no	353.276	355.023	PhosphoSitePlus	COSMIC	232.776	Up-regulation
TK_Tec_TEC_Y	Q06187	BTK	P42680	TEC	Y263	Y268N	268	Missense	distal	5	no	221.232	234.522	EPSD	COSMIC	232.776	Gain
TK_Tec_TEC_Y	Q06187	BTK	P42680	TEC	Y315	T316A	316	Missense	proximal	1	no	255.030	251.100	EPSD	COSMIC	232.776	Down-regulation
TK_Tec_TEC_Y	Q06187	BTK	P42680	TEC	Y315	D308N	308	Missense	distal	-7	no	255.030	258.871	EPSD	COSMIC	232.776	Up-regulation
TK_Tec_TEC_Y	Q06187	BTK	P42680	TEC	Y315	A312P	312	Missense	distal	-3	no	255.030	212.134	EPSD	COSMIC	232.776	Loss
TK_Tec_TEC_Y	Q06187	BTK	P42680	TEC	Y315	V319M	319	Missense	distal	4	no	255.030	268.659	EPSD	COSMIC	232.776	Up-regulation
TK_Tec_TEC_Y	Q06187	BTK	P42680	TEC	Y315	D308Y	308	Missense	distal	-7	no	255.030	247.872	EPSD	COSMIC	232.776	Down-regulation
TK_Tec_TEC_Y	Q06187	BTK	P42680	TEC	Y551	L547Q	547	Missense	distal	-4	no	364.283	365.846	EPSD	COSMIC	232.776	Up-regulation
TK_Tec_TEC_Y	Q06187	BTK	P42680	TEC	Y551	R544W	544	Missense	distal	-7	no	364.283	357.685	EPSD	COSMIC	232.776	Down-regulation
TK_Tec_TEC_Y	Q06187	BTK	P42680	TEC	Y551	S553R	553	Missense	proximal	2	no	364.283	337.542	EPSD	COSMIC	232.776	Down-regulation
TK_Tec_TEC_Y	Q06187	BTK	P42680	TEC	Y551	R544M	544	Missense	distal	-7	no	364.283	362.489	EPSD	COSMIC	232.776	Down-regulation
TK_Tec_TEC_Y	Q06187	BTK	P42680	TEC	Y551	E550K	550	Missense	proximal	-1	no	364.283	364.811	EPSD	COSMIC	232.776	Up-regulation
TK_Tec_TEC_Y	Q08881	ITK	P42680	TEC	Y146	A140T	140	Missense	distal	-6	no	284.658	273.128	EPSD	COSMIC	232.776	Down-regulation
TK_Tec_TEC_Y	Q08881	ITK	P42680	TEC	Y146	A152T	152	Missense	distal	6	no	284.658	262.772	EPSD	COSMIC	232.776	Down-regulation
TK_Tec_TEC_Y	Q08881	ITK	P42680	TEC	Y180	E173A	173	Missense	distal	-7	no	342.208	361.629	PhosphoSitePlus	COSMIC	232.776	Up-regulation
TK_Tec_TEC_Y	Q08881	ITK	P42680	TEC	Y180	P187S	187	Missense	distal	7	no	342.208	340.482	PhosphoSitePlus	COSMIC	232.776	Down-regulation
TK_Tec_TEC_Y	Q08881	ITK	P42680	TEC	Y512	R505T	505	Missense	distal	-7	no	406.594	407.527	EPSD	COSMIC	232.776	Up-regulation
TK_Tec_TEC_Y	Q08881	ITK	P42680	TEC	Y512	D509Y	509	Missense	distal	-3	no	406.594	351.905	EPSD	COSMIC	232.776	Down-regulation
TK_Tec_TEC_Y	Q08881	ITK	P42680	TEC	Y512	V507I	507	Missense	distal	-5	no	406.594	405.814	EPSD	COSMIC	232.776	Down-regulation
TK_Tec_TEC_Y	Q99952	PTPN18	P42680	TEC	Y303	I306S	306	Missense	distal	3	no	277.790	288.431	EPSD;PhosphoSitePlus	COSMIC	232.776	Up-regulation
TK_Tec_TEC_Y	Q99952	PTPN18	P42680	TEC	Y303	A299S	299	Missense	distal	-4	no	277.790	273.508	EPSD;PhosphoSitePlus	COSMIC	232.776	Down-regulation
TK_Tec_TEC_Y	Q99952	PTPN18	P42680	TEC	Y389	A386G	386	Missense	distal	-3	no	368.923	292.558	EPSD;PhosphoSitePlus	COSMIC;CCLE	232.776	Down-regulation
TK_Tec_TEC_Y	P09038	FGF2	P42680	TEC	Y215	R214C	214	Missense	proximal	-1	no	433.447	434.175	EPSD	COSMIC	232.776	Up-regulation
TK_Tec_TEC_Y	P09038	FGF2	P42680	TEC	Y215	D221N	221	Missense	distal	6	no	433.447	432.877	EPSD	COSMIC	232.776	Down-regulation
TK_Tec_TEC_Y	P09038	FGF2	P42680	TEC	Y257	Y257H	257	Missense	central	0	yes	352.187	0.000	EPSD	COSMIC	232.776	Loss
TK_Tec_TEC_Y	P51813	BMX	P42680	TEC	Y202	G203D	203	Missense	proximal	1	no	353.268	351.465	EPSD	COSMIC;GDSC;CCLE	232.776	Down-regulation
TK_Tec_TEC_Y	P51813	BMX	P42680	TEC	Y202	S204P	204	Missense	proximal	2	no	353.268	331.858	EPSD	COSMIC	232.776	Down-regulation
TK_Tec_TEC_Y	P51813	BMX	P42680	TEC	Y202	E197K	197	Missense	distal	-5	no	353.268	351.764	EPSD	COSMIC	232.776	Down-regulation
TK_Tec_TEC_Y	P51813	BMX	P42680	TEC	Y216	T211P	211	Missense	distal	-5	no	389.832	390.703	PhosphoSitePlus	COSMIC	232.776	Up-regulation
TK_Tec_TEC_Y	P51813	BMX	P42680	TEC	Y216	S220L	220	Missense	distal	4	no	389.832	346.739	PhosphoSitePlus	COSMIC	232.776	Down-regulation
TK_Tec_TEC_Y	P51813	BMX	P42680	TEC	Y224	S220L	220	Missense	distal	-4	no	336.946	329.591	EPSD	COSMIC	232.776	Down-regulation
TK_Tec_TEC_Y	P51813	BMX	P42680	TEC	Y224	S226F	226	Missense	proximal	2	no	336.946	291.241	EPSD	COSMIC	232.776	Down-regulation
TK_Tec_TEC_Y	P42680	TEC	P42680	TEC	Y188	G195V	195	Missense	distal	7	no	330.850	331.448	EPSD	COSMIC	232.776	Up-regulation
TK_Tec_TEC_Y	P42680	TEC	P42680	TEC	Y513	Y519C	519	Missense	distal	6	no	302.507	306.577	EPSD	COSMIC	232.776	Up-regulation
TK_Tec_TEC_Y	P42680	TEC	P42680	TEC	Y513	Y513C	513	Missense	central	0	yes	302.507	0.000	EPSD	COSMIC	232.776	Loss
TK_Tec_TEC_Y	P42680	TEC	P42680	TEC	Y513	G509E	509	Missense	distal	-4	no	302.507	306.695	EPSD	COSMIC	232.776	Up-regulation
TK_Tec_TEC_Y	P42680	TEC	P42680	TEC	Y513	D517E	517	Missense	distal	4	no	302.507	305.173	EPSD	COSMIC	232.776	Up-regulation
TK_Tec_TEC_Y	P42680	TEC	P42680	TEC	Y519	Y519C	519	Missense	central	0	yes	424.813	0.000	EPSD	COSMIC	232.776	Loss
TK_Tec_TEC_Y	P42680	TEC	P42680	TEC	Y519	Y513C	513	Missense	distal	-6	no	424.813	426.209	EPSD	COSMIC	232.776	Up-regulation
TK_Tec_TEC_Y	P42680	TEC	P42680	TEC	Y519	D517E	517	Missense	proximal	-2	no	424.813	389.922	EPSD	COSMIC	232.776	Down-regulation
Other_TLK_TLK1_ST	Q99638	RAD9A	Q9UKI8	TLK1	S270	S272C	272	Missense	proximal	2	no	2.666	2.720	EPSD	COSMIC	2.233	Up-regulation
Other_TLK_TLK1_ST	Q99638	RAD9A	Q9UKI8	TLK1	S270	S277T	277	Missense	distal	7	no	2.666	2.595	EPSD	COSMIC	2.233	Down-regulation
Other_TLK_TLK1_ST	Q99638	RAD9A	Q9UKI8	TLK1	S270	D269N	269	Missense	proximal	-1	no	2.666	2.834	EPSD	COSMIC	2.233	Up-regulation
Other_TLK_TLK1_ST	Q99638	RAD9A	Q9UKI8	TLK1	T355	P349H	349	Missense	distal	-6	no	6.265	6.249	EPSD;PhosphoSitePlus	COSMIC	2.233	Down-regulation
Other_TLK_TLK1_ST	Q96PY6	NEK1	Q9UKI8	TLK1	S14	G16A	16	Missense	proximal	2	no	6.636	6.685	EPSD;PhosphoSitePlus	COSMIC	2.233	Up-regulation
Other_TLK_TLK1_ST	Q96PY6	NEK1	Q9UKI8	TLK1	S14	V21A	21	Missense	distal	7	no	6.636	6.987	EPSD;PhosphoSitePlus	COSMIC	2.233	Up-regulation
Other_TLK_TLK1_ST	Q96PY6	NEK1	Q9UKI8	TLK1	T141	K138R	138	Missense	distal	-3	no	6.257	6.165	EPSD;PhosphoSitePlus	COSMIC	2.233	Down-regulation
Other_TLK_TLK1_ST	Q96PY6	NEK1	Q9UKI8	TLK1	S219	S224Y	224	Missense	distal	5	no	2.202	2.271	EPSD	COSMIC	2.233	Gain
Other_TLK_TLK1_ST	Q96PY6	NEK1	Q9UKI8	TLK1	T344	A341T	341	Missense	distal	-3	no	2.213	2.242	EPSD	COSMIC;GDSC	2.233	Gain
Other_TLK_TLK1_ST	Q96PY6	NEK1	Q9UKI8	TLK1	T872	E871K	871	Missense	proximal	-1	no	2.850	3.121	EPSD	COSMIC	2.233	Up-regulation
Other_TLK_TLK1_ST	Q96PY6	NEK1	Q9UKI8	TLK1	T872	E871Q	871	Missense	proximal	-1	no	2.850	2.903	EPSD	COSMIC	2.233	Up-regulation
Other_TLK_TLK1_ST	Q96PY6	NEK1	Q9UKI8	TLK1	T872	E876K	876	Missense	distal	4	no	2.850	3.067	EPSD	COSMIC	2.233	Up-regulation
Other_TLK_TLK1_ST	Q96PY6	NEK1	Q9UKI8	TLK1	T967	D960Y	960	Missense	distal	-7	no	2.398	2.481	EPSD	COSMIC	2.233	Up-regulation
Other_TLK_TLK1_ST	Q96PY6	NEK1	Q9UKI8	TLK1	T967	P965L	965	Missense	proximal	-2	no	2.398	2.435	EPSD	COSMIC	2.233	Up-regulation
Other_TLK_TLK1_ST	Q96PY6	NEK1	Q9UKI8	TLK1	T1050	C1051Y	1051	Missense	proximal	1	no	2.435	2.440	EPSD	COSMIC	2.233	Up-regulation
Other_TLK_TLK1_ST	Q96PY6	NEK1	Q9UKI8	TLK1	T1050	S1052L	1052	Missense	proximal	2	no	2.435	2.449	EPSD	COSMIC	2.233	Up-regulation
Other_TLK_TLK1_ST	Q96PY6	NEK1	Q9UKI8	TLK1	T1050	D1055Y	1055	Missense	distal	5	no	2.435	2.370	EPSD	COSMIC	2.233	Down-regulation
CMGC_CDK_CDC2_CDK1_ST	Q13049	TRIM32	P06493	CDK1	S328	E324D	324	Missense	distal	-4	no	3.556	3.557	EPSD;PhosphoSitePlus	COSMIC	3.158	Up-regulation
CMGC_CDK_CDC2_CDK1_ST	O15151	MDM4	P06493	CDK1	S20	S20C	20	Missense	central	0	yes	3.656	0.000	EPSD	COSMIC	3.158	Loss
CMGC_CDK_CDC2_CDK1_ST	O15151	MDM4	P06493	CDK1	S20	S15R	15	Missense	distal	-5	no	3.656	3.714	EPSD	COSMIC	3.158	Up-regulation
CMGC_CDK_CDC2_CDK1_ST	O15151	MDM4	P06493	CDK1	S20	I24M	24	Missense	distal	4	no	3.656	3.718	EPSD	COSMIC	3.158	Up-regulation
CMGC_CDK_CDC2_CDK1_ST	O15151	MDM4	P06493	CDK1	S20	P21S	21	Missense	proximal	1	no	3.656	0.472	EPSD	COSMIC	3.158	Loss
CMGC_CDK_CDC2_CDK1_ST	O15151	MDM4	P06493	CDK1	S20	D14H	14	Missense	distal	-6	no	3.656	3.658	EPSD	COSMIC	3.158	Up-regulation
CMGC_CDK_CDC2_CDK1_ST	P11388	TOP2A	P06493	CDK1	S802	M809V	809	Missense	distal	7	no	3.372	3.384	EPSD	COSMIC	3.158	Up-regulation
CMGC_CDK_CDC2_CDK1_ST	P11388	TOP2A	P06493	CDK1	S1247	E1242K	1242	Missense	distal	-5	no	3.447	3.478	EPSD;PhosphoSitePlus	COSMIC	3.158	Up-regulation
CMGC_CDK_CDC2_CDK1_ST	Q99638	RAD9A	P06493	CDK1	T292	S291N	291	Missense	proximal	-1	no	3.534	3.626	EPSD;PhosphoSitePlus	COSMIC	3.158	Up-regulation
CMGC_CDK_CDC2_CDK1_ST	Q99638	RAD9A	P06493	CDK1	T292	A299D	299	Missense	distal	7	no	3.534	3.558	EPSD;PhosphoSitePlus	COSMIC	3.158	Up-regulation
CMGC_CDK_CDC2_CDK1_ST	Q99638	RAD9A	P06493	CDK1	S375	P379S	379	Missense	distal	4	no	3.385	3.382	EPSD	COSMIC	3.158	Down-regulation
CMGC_CDK_CDC2_CDK1_ST	Q99638	RAD9A	P06493	CDK1	S380	A384V	384	Missense	distal	4	no	3.427	3.292	EPSD	COSMIC	3.158	Down-regulation
CMGC_CDK_CDC2_CDK1_ST	Q99638	RAD9A	P06493	CDK1	S380	P379S	379	Missense	proximal	-1	no	3.427	3.376	EPSD	COSMIC	3.158	Down-regulation
CMGC_CDK_CDC2_CDK1_ST	P49792	RANBP2	P06493	CDK1	S700	L699R	699	Missense	proximal	-1	no	3.234	3.095	EPSD	COSMIC	3.158	Loss
CMGC_CDK_CDC2_CDK1_ST	P49792	RANBP2	P06493	CDK1	S700	P701R	701	Missense	proximal	1	no	3.234	-0.375	EPSD	COSMIC	3.158	Loss
CMGC_CDK_CDC2_CDK1_ST	P49792	RANBP2	P06493	CDK1	T799	A804T	804	Missense	distal	5	no	3.203	3.267	EPSD	COSMIC;GDSC	3.158	Up-regulation
CMGC_CDK_CDC2_CDK1_ST	P49792	RANBP2	P06493	CDK1	S955	G958A	958	Missense	distal	3	no	3.102	3.277	EPSD	COSMIC	3.158	Gain
CMGC_CDK_CDC2_CDK1_ST	P49792	RANBP2	P06493	CDK1	S1249	M1252I	1252	Missense	distal	3	no	3.568	3.510	EPSD	COSMIC	3.158	Down-regulation
CMGC_CDK_CDC2_CDK1_ST	P49792	RANBP2	P06493	CDK1	S1249	Y1247S	1247	Missense	proximal	-2	no	3.568	3.518	EPSD	COSMIC	3.158	Down-regulation
CMGC_CDK_CDC2_CDK1_ST	P49792	RANBP2	P06493	CDK1	T1255	G1259E	1259	Missense	distal	4	no	3.395	3.458	EPSD	COSMIC	3.158	Up-regulation
CMGC_CDK_CDC2_CDK1_ST	P49792	RANBP2	P06493	CDK1	T1255	M1252I	1252	Missense	distal	-3	no	3.395	3.368	EPSD	COSMIC	3.158	Down-regulation
CMGC_CDK_CDC2_CDK1_ST	P49792	RANBP2	P06493	CDK1	S1400	Q1405E	1405	Missense	distal	5	no	3.092	3.159	EPSD	COSMIC	3.158	Gain
CMGC_CDK_CDC2_CDK1_ST	P49792	RANBP2	P06493	CDK1	T1412	Q1405E	1405	Missense	distal	-7	no	3.716	3.679	EPSD	COSMIC	3.158	Down-regulation
CMGC_CDK_CDC2_CDK1_ST	P49792	RANBP2	P06493	CDK1	S1573	V1578G	1578	Missense	distal	5	no	3.199	3.231	EPSD	COSMIC	3.158	Up-regulation
CMGC_CDK_CDC2_CDK1_ST	P49792	RANBP2	P06493	CDK1	S1573	K1571N	1571	Missense	proximal	-2	no	3.199	3.161	EPSD	COSMIC;GDSC;CCLE	3.158	Down-regulation
CMGC_CDK_CDC2_CDK1_ST	P49792	RANBP2	P06493	CDK1	T1761	S1764C	1764	Missense	distal	3	no	3.468	3.419	EPSD	COSMIC	3.158	Down-regulation
CMGC_CDK_CDC2_CDK1_ST	P49792	RANBP2	P06493	CDK1	T2128	A2132V	2132	Missense	distal	4	no	3.509	3.374	EPSD	COSMIC;GDSC;CCLE	3.158	Down-regulation
CMGC_CDK_CDC2_CDK1_ST	P49792	RANBP2	P06493	CDK1	T2387	T2391S	2391	Missense	distal	4	no	3.318	3.310	EPSD	COSMIC	3.158	Down-regulation
CMGC_CDK_CDC2_CDK1_ST	P49792	RANBP2	P06493	CDK1	S2457	T2458P	2458	Missense	proximal	1	no	0.734	3.167	EPSD	COSMIC	3.158	Gain
CMGC_CDK_CDC2_CDK1_ST	P49792	RANBP2	P06493	CDK1	S2462	T2458P	2458	Missense	distal	-4	no	3.239	3.179	EPSD	COSMIC	3.158	Down-regulation
CMGC_CDK_CDC2_CDK1_ST	P49792	RANBP2	P06493	CDK1	T2504	T2500I	2500	Missense	distal	-4	no	3.196	3.044	EPSD	COSMIC	3.158	Loss
CMGC_CDK_CDC2_CDK1_ST	P30291	WEE1	P06493	CDK1	S127	A129T	129	Missense	proximal	2	no	3.203	3.210	EPSD	COSMIC	3.158	Up-regulation
CMGC_CDK_CDC2_CDK1_ST	Q07820	MCL1	P06493	CDK1	T70	P65L	65	Missense	distal	-5	no	3.139	3.261	EPSD	COSMIC	3.158	Gain
CMGC_CDK_CDC2_CDK1_ST	Q07820	MCL1	P06493	CDK1	T70	A77V	77	Missense	distal	7	no	3.139	3.173	EPSD	COSMIC	3.158	Gain
CMGC_CDK_CDC2_CDK1_ST	Q07820	MCL1	P06493	CDK1	S121	L126M	126	Missense	distal	5	no	3.429	3.285	EPSD	COSMIC	3.158	Down-regulation
CMGC_CDK_CDC2_CDK1_ST	Q07820	MCL1	P06493	CDK1	S121	A116P	116	Missense	distal	-5	no	3.429	3.474	EPSD	COSMIC	3.158	Up-regulation
CMGC_CDK_CDC2_CDK1_ST	Q07820	MCL1	P06493	CDK1	S121	P122L	122	Missense	proximal	1	no	3.429	-0.258	EPSD	COSMIC	3.158	Loss
CMGC_CDK_CDC2_CDK1_ST	Q07820	MCL1	P06493	CDK1	T163	P161F	161	Missense	proximal	-2	no	3.054	3.248	EPSD	COSMIC	3.158	Gain
CMGC_CDK_CDC2_CDK1_ST	Q07820	MCL1	P06493	CDK1	T163	P161H	161	Missense	proximal	-2	no	3.054	3.201	EPSD	COSMIC	3.158	Gain
CMGC_CDK_CDC2_CDK1_ST	Q14980	NUMA1	P06493	CDK1	S77	L81Q	81	Missense	distal	4	no	3.155	3.273	EPSD	COSMIC	3.158	Gain
CMGC_CDK_CDC2_CDK1_ST	Q14980	NUMA1	P06493	CDK1	S112	W116S	116	Missense	distal	4	no	3.226	3.281	EPSD	COSMIC	3.158	Up-regulation
CMGC_CDK_CDC2_CDK1_ST	Q14980	NUMA1	P06493	CDK1	S112	P113H	113	Missense	proximal	1	no	3.226	0.542	EPSD	COSMIC	3.158	Loss
CMGC_CDK_CDC2_CDK1_ST	Q14980	NUMA1	P06493	CDK1	S1862	S1856R	1856	Missense	distal	-6	no	3.168	3.175	EPSD	COSMIC	3.158	Up-regulation
CMGC_CDK_CDC2_CDK1_ST	Q14980	NUMA1	P06493	CDK1	S1862	L1857V	1857	Missense	distal	-5	no	3.168	3.141	EPSD	COSMIC	3.158	Loss
CMGC_CDK_CDC2_CDK1_ST	Q96FF9	CDCA5	P06493	CDK1	S21	R18K	18	Missense	distal	-3	no	3.327	3.316	EPSD;PhosphoSitePlus	COSMIC	3.158	Down-regulation
CMGC_CDK_CDC2_CDK1_ST	Q96FF9	CDCA5	P06493	CDK1	S21	G16R	16	Missense	distal	-5	no	3.327	3.259	EPSD;PhosphoSitePlus	COSMIC	3.158	Down-regulation
CMGC_CDK_CDC2_CDK1_ST	Q96FF9	CDCA5	P06493	CDK1	S79	R81S	81	Missense	proximal	2	no	3.218	3.211	EPSD;PhosphoSitePlus	COSMIC	3.158	Down-regulation
CMGC_CDK_CDC2_CDK1_ST	Q96FF9	CDCA5	P06493	CDK1	S154	G161S	161	Missense	distal	7	no	3.197	3.170	EPSD	COSMIC	3.158	Down-regulation
CMGC_CDK_CDC2_CDK1_ST	P10636	MAPT	P06493	CDK1	T492	R487G	487	Missense	distal	-5	no	3.121	3.190	EPSD	COSMIC	3.158	Gain
CMGC_CDK_CDC2_CDK1_ST	P10636	MAPT	P06493	CDK1	T498	K491R	491	Missense	distal	-7	no	3.296	3.373	EPSD	COSMIC	3.158	Up-regulation
CMGC_CDK_CDC2_CDK1_ST	P10636	MAPT	P06493	CDK1	T498	A495T	495	Missense	distal	-3	no	3.296	3.259	EPSD	COSMIC	3.158	Down-regulation
CMGC_CDK_CDC2_CDK1_ST	P10636	MAPT	P06493	CDK1	T498	P493L	493	Missense	distal	-5	no	3.296	3.418	EPSD	COSMIC	3.158	Up-regulation
CMGC_CDK_CDC2_CDK1_ST	P10636	MAPT	P06493	CDK1	T529	R526H	526	Missense	distal	-3	no	3.170	3.180	EPSD	COSMIC	3.158	Up-regulation
CMGC_CDK_CDC2_CDK1_ST	P10636	MAPT	P06493	CDK1	T529	R528S	528	Missense	proximal	-1	no	3.170	3.107	EPSD	COSMIC	3.158	Loss
CMGC_CDK_CDC2_CDK1_ST	P10636	MAPT	P06493	CDK1	T529	P530S	530	Missense	proximal	1	no	3.170	-0.015	EPSD	COSMIC	3.158	Loss
CMGC_CDK_CDC2_CDK1_ST	P10636	MAPT	P06493	CDK1	T529	P536H	536	Missense	distal	7	no	3.170	3.177	EPSD	COSMIC	3.158	Up-regulation
CMGC_CDK_CDC2_CDK1_ST	P10636	MAPT	P06493	CDK1	T529	P535Q	535	Missense	distal	6	no	3.170	3.166	EPSD	COSMIC	3.158	Down-regulation
CMGC_CDK_CDC2_CDK1_ST	P10636	MAPT	P06493	CDK1	T534	R528S	528	Missense	distal	-6	no	3.508	3.501	EPSD	COSMIC	3.158	Down-regulation
CMGC_CDK_CDC2_CDK1_ST	P10636	MAPT	P06493	CDK1	T534	P530S	530	Missense	distal	-4	no	3.508	3.559	EPSD	COSMIC	3.158	Up-regulation
CMGC_CDK_CDC2_CDK1_ST	P10636	MAPT	P06493	CDK1	T534	P536H	536	Missense	proximal	2	no	3.508	3.518	EPSD	COSMIC	3.158	Up-regulation
CMGC_CDK_CDC2_CDK1_ST	P10636	MAPT	P06493	CDK1	T534	P535Q	535	Missense	proximal	1	no	3.508	1.085	EPSD	COSMIC	3.158	Loss
CMGC_CDK_CDC2_CDK1_ST	P10636	MAPT	P06493	CDK1	T534	E539Q	539	Missense	distal	5	no	3.508	3.442	EPSD	COSMIC	3.158	Down-regulation
CMGC_CDK_CDC2_CDK1_ST	P10636	MAPT	P06493	CDK1	T548	P550S	550	Missense	proximal	2	no	3.556	3.554	EPSD	COSMIC	3.158	Down-regulation
CMGC_CDK_CDC2_CDK1_ST	P10636	MAPT	P06493	CDK1	T548	P553R	553	Missense	distal	5	no	3.556	3.518	EPSD	COSMIC	3.158	Down-regulation
CMGC_CDK_CDC2_CDK1_ST	P10636	MAPT	P06493	CDK1	T548	P553L	553	Missense	distal	5	no	3.556	3.740	EPSD	COSMIC	3.158	Up-regulation
CMGC_CDK_CDC2_CDK1_ST	P10636	MAPT	P06493	CDK1	T548	P549L	549	Missense	proximal	1	no	3.556	-0.131	EPSD	COSMIC	3.158	Loss
CMGC_CDK_CDC2_CDK1_ST	P10636	MAPT	P06493	CDK1	T548	S555F	555	Missense	distal	7	no	3.556	3.578	EPSD	COSMIC	3.158	Up-regulation
CMGC_CDK_CDC2_CDK1_ST	P10636	MAPT	P06493	CDK1	T548	P553Q	553	Missense	distal	5	no	3.556	3.541	EPSD	COSMIC	3.158	Down-regulation
CMGC_CDK_CDC2_CDK1_ST	P10636	MAPT	P06493	CDK1	S713	G706R	706	Missense	distal	-7	no	3.136	3.258	EPSD	COSMIC	3.158	Gain
CMGC_CDK_CDC2_CDK1_ST	P10636	MAPT	P06493	CDK1	S713	E708K	708	Missense	distal	-5	no	3.136	3.166	EPSD	COSMIC	3.158	Gain
CMGC_CDK_CDC2_CDK1_ST	P10636	MAPT	P06493	CDK1	S713	V710A	710	Missense	distal	-3	no	3.136	3.198	EPSD	COSMIC	3.158	Gain
CMGC_CDK_CDC2_CDK1_ST	Q99728	BARD1	P06493	CDK1	S288	E287G	287	Missense	proximal	-1	no	3.330	3.457	EPSD;PhosphoSitePlus	COSMIC	3.158	Up-regulation
CMGC_CDK_CDC2_CDK1_ST	Q99728	BARD1	P06493	CDK1	S288	R294S	294	Missense	distal	6	no	3.330	3.324	EPSD;PhosphoSitePlus	COSMIC	3.158	Down-regulation
CMGC_CDK_CDC2_CDK1_ST	Q99728	BARD1	P06493	CDK1	S288	K292N	292	Missense	distal	4	no	3.330	3.326	EPSD;PhosphoSitePlus	COSMIC	3.158	Down-regulation
CMGC_CDK_CDC2_CDK1_ST	Q99728	BARD1	P06493	CDK1	S288	D290H	290	Missense	proximal	2	no	3.330	3.332	EPSD;PhosphoSitePlus	COSMIC	3.158	Up-regulation
CMGC_CDK_CDC2_CDK1_ST	Q99728	BARD1	P06493	CDK1	S288	A283V	283	Missense	distal	-5	no	3.330	3.470	EPSD;PhosphoSitePlus	COSMIC	3.158	Up-regulation
CMGC_CDK_CDC2_CDK1_ST	Q99728	BARD1	P06493	CDK1	S288	L282F	282	Missense	distal	-6	no	3.330	3.326	EPSD;PhosphoSitePlus	COSMIC	3.158	Down-regulation
CMGC_CDK_CDC2_CDK1_ST	Q99728	BARD1	P06493	CDK1	S288	S288C	288	Missense	central	0	yes	3.330	0.000	EPSD;PhosphoSitePlus	COSMIC	3.158	Loss
CMGC_CDK_CDC2_CDK1_ST	Q99728	BARD1	P06493	CDK1	S288	E287A	287	Missense	proximal	-1	no	3.330	3.183	EPSD;PhosphoSitePlus	COSMIC	3.158	Down-regulation
CMGC_CDK_CDC2_CDK1_ST	Q99728	BARD1	P06493	CDK1	S288	P281T	281	Missense	distal	-7	no	3.330	3.391	EPSD;PhosphoSitePlus	COSMIC	3.158	Up-regulation
CMGC_CDK_CDC2_CDK1_ST	Q99728	BARD1	P06493	CDK1	S496	T490P	490	Missense	distal	-6	no	3.257	3.260	EPSD	COSMIC	3.158	Up-regulation
CMGC_CDK_CDC2_CDK1_ST	Q99728	BARD1	P06493	CDK1	S496	T489I	489	Missense	distal	-7	no	3.257	3.084	EPSD	COSMIC	3.158	Loss
CMGC_CDK_CDC2_CDK1_ST	Q99728	BARD1	P06493	CDK1	S496	D500H	500	Missense	distal	4	no	3.257	3.278	EPSD	COSMIC	3.158	Up-regulation
CMGC_CDK_CDC2_CDK1_ST	Q99728	BARD1	P06493	CDK1	S496	G491R	491	Missense	distal	-5	no	3.257	3.189	EPSD	COSMIC	3.158	Down-regulation
CMGC_CDK_CDC2_CDK1_ST	Q99728	BARD1	P06493	CDK1	S496	A502N	502	Missense	distal	6	no	3.257	3.231	EPSD	COSMIC	3.158	Down-regulation
CMGC_CDK_CDC2_CDK1_ST	Q99728	BARD1	P06493	CDK1	S496	T490I	490	Missense	distal	-6	no	3.257	3.281	EPSD	COSMIC	3.158	Up-regulation
CMGC_CDK_CDC2_CDK1_ST	Q99728	BARD1	P06493	CDK1	S496	H499Y	499	Missense	distal	3	no	3.257	3.203	EPSD	COSMIC	3.158	Down-regulation
CMGC_CDK_CDC2_CDK1_ST	Q99728	BARD1	P06493	CDK1	S496	P497L	497	Missense	proximal	1	no	3.257	-0.429	EPSD	COSMIC	3.158	Loss
CMGC_CDK_CDC2_CDK1_ST	Q99728	BARD1	P06493	CDK1	S496	S496A	496	Missense	central	0	yes	3.257	0.000	EPSD	COSMIC	3.158	Loss
CMGC_CDK_CDC2_CDK1_ST	Q99728	BARD1	P06493	CDK1	S496	S496F	496	Missense	central	0	yes	3.257	0.000	EPSD	COSMIC	3.158	Loss
CMGC_CDK_CDC2_CDK1_ST	Q9NXR1	NDE1	P06493	CDK1	T243	P244S	244	Missense	proximal	1	no	3.620	0.435	EPSD;PhosphoSitePlus	COSMIC	3.158	Loss
CMGC_CDK_CDC2_CDK1_ST	Q9NXR1	NDE1	P06493	CDK1	T246	P244S	244	Missense	proximal	-2	no	4.229	4.355	EPSD;PhosphoSitePlus	COSMIC	3.158	Up-regulation
CMGC_CDK_CDC2_CDK1_ST	Q9NXR1	NDE1	P06493	CDK1	S333	S331P	331	Missense	proximal	-2	no	3.202	3.076	EPSD	COSMIC	3.158	Loss
CMGC_CDK_CDC2_CDK1_ST	P21333	FLNA	P06493	CDK1	S564	R563C	563	Missense	proximal	-1	no	3.192	3.246	EPSD	COSMIC;GDSC;CCLE	3.158	Up-regulation
CMGC_CDK_CDC2_CDK1_ST	P21333	FLNA	P06493	CDK1	S564	E567G	567	Missense	distal	3	no	3.192	3.121	EPSD	COSMIC	3.158	Loss
CMGC_CDK_CDC2_CDK1_ST	P21333	FLNA	P06493	CDK1	S564	R563H	563	Missense	proximal	-1	no	3.192	3.215	EPSD	COSMIC	3.158	Up-regulation
CMGC_CDK_CDC2_CDK1_ST	P21333	FLNA	P06493	CDK1	S564	S564C	564	Missense	central	0	yes	3.192	0.000	EPSD	COSMIC	3.158	Loss
CMGC_CDK_CDC2_CDK1_ST	P21333	FLNA	P06493	CDK1	S564	G562R	562	Missense	proximal	-2	no	3.192	3.169	EPSD	COSMIC	3.158	Down-regulation
CMGC_CDK_CDC2_CDK1_ST	P21333	FLNA	P06493	CDK1	S564	G562S	562	Missense	proximal	-2	no	3.192	3.102	EPSD	COSMIC	3.158	Loss
CMGC_CDK_CDC2_CDK1_ST	P21333	FLNA	P06493	CDK1	S959	S959R	959	Missense	central	0	yes	3.387	0.000	EPSD	COSMIC	3.158	Loss
CMGC_CDK_CDC2_CDK1_ST	P21333	FLNA	P06493	CDK1	S966	S959R	959	Missense	distal	-7	no	3.404	3.368	EPSD	COSMIC	3.158	Down-regulation
CMGC_CDK_CDC2_CDK1_ST	P21333	FLNA	P06493	CDK1	S1055	G1054A	1054	Missense	proximal	-1	no	3.229	2.955	EPSD	COSMIC	3.158	Loss
CMGC_CDK_CDC2_CDK1_ST	P21333	FLNA	P06493	CDK1	S1055	P1058S	1058	Missense	distal	3	no	3.229	3.279	EPSD	COSMIC	3.158	Up-regulation
CMGC_CDK_CDC2_CDK1_ST	P21333	FLNA	P06493	CDK1	S1084	A1086T	1086	Missense	proximal	2	no	3.355	3.362	EPSD;PhosphoSitePlus	COSMIC;CCLE	3.158	Up-regulation
CMGC_CDK_CDC2_CDK1_ST	P21333	FLNA	P06493	CDK1	S1084	R1087C	1087	Missense	distal	3	no	3.355	3.236	EPSD;PhosphoSitePlus	COSMIC;GDSC	3.158	Down-regulation
CMGC_CDK_CDC2_CDK1_ST	P21333	FLNA	P06493	CDK1	S2033	G2027A	2027	Missense	distal	-6	no	3.370	3.346	EPSD	COSMIC	3.158	Down-regulation
CMGC_CDK_CDC2_CDK1_ST	P21333	FLNA	P06493	CDK1	S2033	P2036Q	2036	Missense	distal	3	no	3.370	3.442	EPSD	COSMIC	3.158	Up-regulation
CMGC_CDK_CDC2_CDK1_ST	P21333	FLNA	P06493	CDK1	S2033	A2031V	2031	Missense	proximal	-2	no	3.370	3.535	EPSD	COSMIC	3.158	Up-regulation
CMGC_CDK_CDC2_CDK1_ST	P21333	FLNA	P06493	CDK1	S2033	S2040R	2040	Missense	distal	7	no	3.370	3.378	EPSD	COSMIC	3.158	Up-regulation
CMGC_CDK_CDC2_CDK1_ST	P21333	FLNA	P06493	CDK1	S2033	S2040L	2040	Missense	distal	7	no	3.370	3.400	EPSD	COSMIC	3.158	Up-regulation
CMGC_CDK_CDC2_CDK1_ST	P21333	FLNA	P06493	CDK1	S2033	G2027V	2027	Missense	distal	-6	no	3.370	3.367	EPSD	COSMIC	3.158	Down-regulation
CMGC_CDK_CDC2_CDK1_ST	P21333	FLNA	P06493	CDK1	S2180	G2183A	2183	Missense	distal	3	no	3.165	3.341	EPSD	COSMIC	3.158	Up-regulation
CMGC_CDK_CDC2_CDK1_ST	P21333	FLNA	P06493	CDK1	S2180	S2182L	2182	Missense	proximal	2	no	3.165	3.188	EPSD	COSMIC	3.158	Up-regulation
CMGC_CDK_CDC2_CDK1_ST	P21333	FLNA	P06493	CDK1	S2180	K2184R	2184	Missense	distal	4	no	3.165	3.196	EPSD	COSMIC	3.158	Up-regulation
CMGC_CDK_CDC2_CDK1_ST	P21333	FLNA	P06493	CDK1	S2224	G2218D	2218	Missense	distal	-6	no	3.485	3.472	EPSD	COSMIC;GDSC;CCLE	3.158	Down-regulation
CMGC_CDK_CDC2_CDK1_ST	P21333	FLNA	P06493	CDK1	S2224	G2223W	2223	Missense	proximal	-1	no	3.485	3.398	EPSD	COSMIC	3.158	Down-regulation
CMGC_CDK_CDC2_CDK1_ST	P21333	FLNA	P06493	CDK1	T2488	R2484C	2484	Missense	distal	-4	no	3.302	3.233	EPSD	COSMIC	3.158	Down-regulation
CMGC_CDK_CDC2_CDK1_ST	P21333	FLNA	P06493	CDK1	T2488	E2481D	2481	Missense	distal	-7	no	3.302	3.309	EPSD	COSMIC	3.158	Up-regulation
CMGC_CDK_CDC2_CDK1_ST	P21333	FLNA	P06493	CDK1	T2488	R2484S	2484	Missense	distal	-4	no	3.302	3.368	EPSD	COSMIC	3.158	Up-regulation
CMGC_CDK_CDC2_CDK1_ST	P21333	FLNA	P06493	CDK1	T2488	Y2483C	2483	Missense	distal	-5	no	3.302	3.312	EPSD	COSMIC	3.158	Up-regulation
CMGC_CDK_CDC2_CDK1_ST	P21333	FLNA	P06493	CDK1	S2510	P2504S	2504	Missense	distal	-6	no	4.141	4.140	EPSD	COSMIC	3.158	Down-regulation
CMGC_CDK_CDC2_CDK1_ST	P21333	FLNA	P06493	CDK1	S2510	P2511L	2511	Missense	proximal	1	no	4.141	0.455	EPSD	COSMIC	3.158	Loss
CMGC_CDK_CDC2_CDK1_ST	P21333	FLNA	P06493	CDK1	S2510	S2510F	2510	Missense	central	0	yes	4.141	0.000	EPSD	COSMIC	3.158	Loss
CMGC_CDK_CDC2_CDK1_ST	P21333	FLNA	P06493	CDK1	T2599	G2596S	2596	Missense	distal	-3	no	3.119	3.173	EPSD	COSMIC	3.158	Gain
CMGC_CDK_CDC2_CDK1_ST	P21333	FLNA	P06493	CDK1	S2640	P2641L	2641	Missense	proximal	1	no	3.246	-0.440	EPSD	COSMIC	3.158	Loss
CMGC_CDK_CDC2_CDK1_ST	P21333	FLNA	P06493	CDK1	S2640	R2643C	2643	Missense	distal	3	no	3.246	3.127	EPSD	COSMIC	3.158	Loss
CMGC_CDK_CDC2_CDK1_ST	P08047	SP1	P06493	CDK1	T745	T746P	746	Missense	proximal	1	no	0.943	3.377	EPSD	COSMIC	3.158	Gain
CMGC_CDK_CDC2_CDK1_ST	P19338	NCL	P06493	CDK1	S67	V65A	65	Missense	proximal	-2	no	3.190	3.025	EPSD	COSMIC;CCLE	3.158	Loss
CMGC_CDK_CDC2_CDK1_ST	P19338	NCL	P06493	CDK1	S67	V66I	66	Missense	proximal	-1	no	3.190	3.243	EPSD	COSMIC	3.158	Up-regulation
CMGC_CDK_CDC2_CDK1_ST	P19338	NCL	P06493	CDK1	T99	V98I	98	Missense	proximal	-1	no	3.806	3.859	EPSD	COSMIC	3.158	Up-regulation
CMGC_CDK_CDC2_CDK1_ST	P19338	NCL	P06493	CDK1	T99	P93H	93	Missense	distal	-6	no	3.806	3.816	EPSD	COSMIC	3.158	Up-regulation
CMGC_CDK_CDC2_CDK1_ST	P19338	NCL	P06493	CDK1	T113	V119A	119	Missense	distal	6	no	3.440	3.488	EPSD	COSMIC	3.158	Up-regulation
CMGC_CDK_CDC2_CDK1_ST	P19338	NCL	P06493	CDK1	T121	V119A	119	Missense	proximal	-2	no	3.354	3.189	PhosphoSitePlus;EPSD	COSMIC	3.158	Down-regulation
CMGC_CDK_CDC2_CDK1_ST	P19338	NCL	P06493	CDK1	T121	P122L	122	Missense	proximal	1	no	3.354	-0.332	PhosphoSitePlus;EPSD	COSMIC	3.158	Loss
CMGC_CDK_CDC2_CDK1_ST	Q14135	VGLL4	P06493	CDK1	S103	E99K	99	Missense	distal	-4	no	3.240	3.187	EPSD	COSMIC	3.158	Down-regulation
CMGC_CDK_CDC2_CDK1_ST	Q14135	VGLL4	P06493	CDK1	S103	R98L	98	Missense	distal	-5	no	3.240	3.326	EPSD	COSMIC	3.158	Up-regulation
CMGC_CDK_CDC2_CDK1_ST	Q14135	VGLL4	P06493	CDK1	S103	D96A	96	Missense	distal	-7	no	3.240	3.328	EPSD	COSMIC	3.158	Up-regulation
CMGC_CDK_CDC2_CDK1_ST	Q14135	VGLL4	P06493	CDK1	S103	R100L	100	Missense	distal	-3	no	3.240	3.235	EPSD	COSMIC	3.158	Down-regulation
CMGC_CDK_CDC2_CDK1_ST	Q14135	VGLL4	P06493	CDK1	S103	A108T	108	Missense	distal	5	no	3.240	3.304	EPSD	COSMIC	3.158	Up-regulation
CMGC_CDK_CDC2_CDK1_ST	Q14135	VGLL4	P06493	CDK1	S103	E99D	99	Missense	distal	-4	no	3.240	3.241	EPSD	COSMIC	3.158	Up-regulation
CMGC_CDK_CDC2_CDK1_ST	Q14135	VGLL4	P06493	CDK1	S103	R107C	107	Missense	distal	4	no	3.240	3.176	EPSD	COSMIC	3.158	Down-regulation
CMGC_CDK_CDC2_CDK1_ST	Q06830	PRDX1	P06493	CDK1	T18	A19P	19	Missense	proximal	1	no	2.855	3.744	EPSD	COSMIC	3.158	Gain
CMGC_CDK_CDC2_CDK1_ST	O95139	NDUFB6	P06493	CDK1	T5	G3W	3	Missense	proximal	-2	no	3.205	3.154	EPSD;PhosphoSitePlus	COSMIC	3.158	Loss
CMGC_CDK_CDC2_CDK1_ST	O95139	NDUFB6	P06493	CDK1	T5	D7Y	7	Missense	proximal	2	no	3.205	3.210	EPSD;PhosphoSitePlus	COSMIC;GDSC;CCLE	3.158	Up-regulation
CMGC_CDK_CDC2_CDK1_ST	O95139	NDUFB6	P06493	CDK1	S29	L23R	23	Missense	distal	-6	no	3.676	3.655	PhosphoSitePlus;EPSD	COSMIC	3.158	Down-regulation
CMGC_CDK_CDC2_CDK1_ST	O95139	NDUFB6	P06493	CDK1	S29	Q26E	26	Missense	distal	-3	no	3.676	3.654	PhosphoSitePlus;EPSD	COSMIC	3.158	Down-regulation
CMGC_CDK_CDC2_CDK1_ST	O95139	NDUFB6	P06493	CDK1	S29	E32V	32	Missense	distal	3	no	3.676	3.628	PhosphoSitePlus;EPSD	COSMIC	3.158	Down-regulation
CMGC_CDK_CDC2_CDK1_ST	O95139	NDUFB6	P06493	CDK1	S55	F50C	50	Missense	distal	-5	no	3.931	3.911	EPSD;PhosphoSitePlus	COSMIC	3.158	Down-regulation
CMGC_CDK_CDC2_CDK1_ST	O95139	NDUFB6	P06493	CDK1	S55	K59E	59	Missense	distal	4	no	3.931	3.900	EPSD;PhosphoSitePlus	COSMIC	3.158	Down-regulation
CMGC_CDK_CDC2_CDK1_ST	P18031	PTPN1	P06493	CDK1	S50	I57V	57	Missense	distal	7	no	3.524	3.522	EPSD	COSMIC;GDSC;CCLE	3.158	Down-regulation
CMGC_CDK_CDC2_CDK1_ST	P18031	PTPN1	P06493	CDK1	S386	P392L	392	Missense	distal	6	no	3.252	3.196	PhosphoSitePlus	COSMIC	3.158	Down-regulation
CMGC_CDK_CDC2_CDK1_ST	P18031	PTPN1	P06493	CDK1	S386	P387T	387	Missense	proximal	1	no	3.252	0.819	PhosphoSitePlus	COSMIC	3.158	Loss
CMGC_CDK_CDC2_CDK1_ST	P18031	PTPN1	P06493	CDK1	S386	A385S	385	Missense	proximal	-1	no	3.252	3.306	PhosphoSitePlus	COSMIC	3.158	Up-regulation
CMGC_CDK_CDC2_CDK1_ST	P18031	PTPN1	P06493	CDK1	S386	A385V	385	Missense	proximal	-1	no	3.252	3.452	PhosphoSitePlus	COSMIC	3.158	Up-regulation
CMGC_CDK_CDC2_CDK1_ST	P18031	PTPN1	P06493	CDK1	S386	K389N	389	Missense	distal	3	no	3.252	3.204	PhosphoSitePlus	COSMIC	3.158	Down-regulation
CMGC_CDK_CDC2_CDK1_ST	P18031	PTPN1	P06493	CDK1	S386	P387L	387	Missense	proximal	1	no	3.252	-0.434	PhosphoSitePlus	COSMIC	3.158	Loss
CMGC_CDK_CDC2_CDK1_ST	Q96R06	SPAG5	P06493	CDK1	S66	N73S	73	Missense	distal	7	no	3.316	3.309	EPSD	COSMIC	3.158	Down-regulation
CMGC_CDK_CDC2_CDK1_ST	Q96R06	SPAG5	P06493	CDK1	T111	T114M	114	Missense	distal	3	no	3.377	3.373	EPSD	COSMIC	3.158	Down-regulation
CMGC_CDK_CDC2_CDK1_ST	Q96R06	SPAG5	P06493	CDK1	S341	K348E	348	Missense	distal	7	no	3.275	3.279	EPSD	COSMIC;GDSC;CCLE	3.158	Up-regulation
CMGC_CDK_CDC2_CDK1_ST	Q96R06	SPAG5	P06493	CDK1	S341	D335N	335	Missense	distal	-6	no	3.275	3.273	EPSD	COSMIC	3.158	Down-regulation
CMGC_CDK_CDC2_CDK1_ST	Q96R06	SPAG5	P06493	CDK1	T963	A961T	961	Missense	proximal	-2	no	3.210	3.291	EPSD	COSMIC	3.158	Up-regulation
CMGC_CDK_CDC2_CDK1_ST	Q96R06	SPAG5	P06493	CDK1	T963	M966I	966	Missense	distal	3	no	3.210	3.152	EPSD	COSMIC	3.158	Loss
CMGC_CDK_CDC2_CDK1_ST	Q9NTI5	PDS5B	P06493	CDK1	S1283	P1284A	1284	Missense	proximal	1	no	3.284	2.395	EPSD	COSMIC	3.158	Loss
CMGC_CDK_CDC2_CDK1_ST	Q9NTI5	PDS5B	P06493	CDK1	S1283	R1290T	1290	Missense	distal	7	no	3.284	3.279	EPSD	COSMIC	3.158	Down-regulation
CMGC_CDK_CDC2_CDK1_ST	Q14CB8	ARHGAP19	P06493	CDK1	S470	L465I	465	Missense	distal	-5	no	3.384	3.371	EPSD	COSMIC	3.158	Down-regulation
CMGC_CDK_CDC2_CDK1_ST	Q14CB8	ARHGAP19	P06493	CDK1	S470	L465F	465	Missense	distal	-5	no	3.384	3.351	EPSD	COSMIC	3.158	Down-regulation
CMGC_CDK_CDC2_CDK1_ST	Q9H8V3	ECT2	P06493	CDK1	S121	P122A	122	Missense	proximal	1	no	3.520	2.631	EPSD	COSMIC	3.158	Loss
CMGC_CDK_CDC2_CDK1_ST	Q9H8V3	ECT2	P06493	CDK1	S121	E123Q	123	Missense	proximal	2	no	3.520	3.513	EPSD	COSMIC	3.158	Down-regulation
CMGC_CDK_CDC2_CDK1_ST	Q9H8V3	ECT2	P06493	CDK1	S397	R402H	402	Missense	distal	5	no	3.412	3.477	EPSD	COSMIC	3.158	Up-regulation
CMGC_CDK_CDC2_CDK1_ST	Q9H8V3	ECT2	P06493	CDK1	S397	E393G	393	Missense	distal	-4	no	3.412	3.333	EPSD	COSMIC	3.158	Down-regulation
CMGC_CDK_CDC2_CDK1_ST	Q9H8V3	ECT2	P06493	CDK1	T444	S439F	439	Missense	distal	-5	no	3.438	3.548	EPSD;PhosphoSitePlus	COSMIC	3.158	Up-regulation
CMGC_CDK_CDC2_CDK1_ST	Q9H8V3	ECT2	P06493	CDK1	T444	T437S	437	Missense	distal	-7	no	3.438	3.417	EPSD;PhosphoSitePlus	COSMIC	3.158	Down-regulation
CMGC_CDK_CDC2_CDK1_ST	Q9H8V3	ECT2	P06493	CDK1	S716	H718Y	718	Missense	proximal	2	no	3.595	3.600	EPSD	COSMIC	3.158	Up-regulation
CMGC_CDK_CDC2_CDK1_ST	Q9H8V3	ECT2	P06493	CDK1	T822	L823P	823	Missense	proximal	1	no	-0.493	3.193	EPSD	COSMIC	3.158	Gain
CMGC_CDK_CDC2_CDK1_ST	O14757	CHEK1	P06493	CDK1	T362	L360F	360	Missense	proximal	-2	no	3.499	3.519	EPSD	COSMIC	3.158	Up-regulation
CMGC_CDK_CDC2_CDK1_ST	O14757	CHEK1	P06493	CDK1	T362	G361D	361	Missense	proximal	-1	no	3.499	3.364	EPSD	COSMIC;GDSC;CCLE	3.158	Down-regulation
CMGC_CDK_CDC2_CDK1_ST	Q14978	NOLC1	P06493	CDK1	T259	T259I	259	Missense	central	0	yes	3.207	0.000	EPSD	COSMIC	3.158	Loss
CMGC_CDK_CDC2_CDK1_ST	Q14978	NOLC1	P06493	CDK1	T259	R262W	262	Missense	distal	3	no	3.207	3.078	EPSD	COSMIC;GDSC;CCLE	3.158	Loss
CMGC_CDK_CDC2_CDK1_ST	Q14978	NOLC1	P06493	CDK1	T259	T258I	258	Missense	proximal	-1	no	3.207	3.432	EPSD	COSMIC	3.158	Up-regulation
CMGC_CDK_CDC2_CDK1_ST	Q13586	STIM1	P06493	CDK1	S486	M480I	480	Missense	distal	-6	no	3.259	3.272	EPSD	COSMIC	3.158	Up-regulation
CMGC_CDK_CDC2_CDK1_ST	Q13586	STIM1	P06493	CDK1	S600	L599M	599	Missense	proximal	-1	no	3.181	3.068	EPSD	COSMIC	3.158	Loss
CMGC_CDK_CDC2_CDK1_ST	Q13586	STIM1	P06493	CDK1	S600	A593S	593	Missense	distal	-7	no	3.181	3.154	EPSD	COSMIC	3.158	Loss
CMGC_CDK_CDC2_CDK1_ST	Q96T88	UHRF1	P06493	CDK1	S287	P288L	288	Missense	proximal	1	no	3.279	-0.407	EPSD	COSMIC	3.158	Loss
CMGC_CDK_CDC2_CDK1_ST	Q96T88	UHRF1	P06493	CDK1	S287	P288S	288	Missense	proximal	1	no	3.279	0.095	EPSD	COSMIC	3.158	Loss
CMGC_CDK_CDC2_CDK1_ST	Q96T88	UHRF1	P06493	CDK1	S287	R282Q	282	Missense	distal	-5	no	3.279	3.247	EPSD	COSMIC	3.158	Down-regulation
CMGC_CDK_CDC2_CDK1_ST	Q96T88	UHRF1	P06493	CDK1	S287	P293L	293	Missense	distal	6	no	3.279	3.223	EPSD	COSMIC	3.158	Down-regulation
CMGC_CDK_CDC2_CDK1_ST	Q96T88	UHRF1	P06493	CDK1	S709	R704W	704	Missense	distal	-5	no	3.634	3.659	EPSD	COSMIC	3.158	Up-regulation
CMGC_CDK_CDC2_CDK1_ST	Q96T88	UHRF1	P06493	CDK1	S709	F714L	714	Missense	distal	5	no	3.634	3.681	EPSD	COSMIC	3.158	Up-regulation
CMGC_CDK_CDC2_CDK1_ST	Q96T88	UHRF1	P06493	CDK1	S709	P710L	710	Missense	proximal	1	no	3.634	-0.052	EPSD	COSMIC	3.158	Loss
CMGC_CDK_CDC2_CDK1_ST	Q96T88	UHRF1	P06493	CDK1	S709	P705L	705	Missense	distal	-4	no	3.634	3.491	EPSD	COSMIC	3.158	Down-regulation
CMGC_CDK_CDC2_CDK1_ST	P11171	EPB41	P06493	CDK1	T378	Q381H	381	Missense	distal	3	no	3.239	3.195	EPSD	COSMIC	3.158	Down-regulation
CMGC_CDK_CDC2_CDK1_ST	P11171	EPB41	P06493	CDK1	T378	A382D	382	Missense	distal	4	no	3.239	3.134	EPSD	COSMIC	3.158	Loss
CMGC_CDK_CDC2_CDK1_ST	P11171	EPB41	P06493	CDK1	T378	Q381L	381	Missense	distal	3	no	3.239	3.034	EPSD	COSMIC	3.158	Loss
CMGC_CDK_CDC2_CDK1_ST	P11171	EPB41	P06493	CDK1	S712	R707S	707	Missense	distal	-5	no	3.336	3.278	EPSD	COSMIC	3.158	Down-regulation
CMGC_CDK_CDC2_CDK1_ST	P11171	EPB41	P06493	CDK1	S712	I719F	719	Missense	distal	7	no	3.336	3.332	EPSD	COSMIC	3.158	Down-regulation
CMGC_CDK_CDC2_CDK1_ST	P11171	EPB41	P06493	CDK1	S712	N718I	718	Missense	distal	6	no	3.336	3.302	EPSD	COSMIC	3.158	Down-regulation
CMGC_CDK_CDC2_CDK1_ST	Q9Y6I3	EPN1	P06493	CDK1	S454	A449T	449	Missense	distal	-5	no	3.137	3.158	EPSD	COSMIC	3.158	Gain
CMGC_CDK_CDC2_CDK1_ST	Q9Y6I3	EPN1	P06493	CDK1	T462	T464A	464	Missense	proximal	2	no	3.734	3.728	EPSD	COSMIC	3.158	Down-regulation
CMGC_CDK_CDC2_CDK1_ST	Q9Y6I3	EPN1	P06493	CDK1	T462	T467N	467	Missense	distal	5	no	3.734	3.768	EPSD	COSMIC	3.158	Up-regulation
CMGC_CDK_CDC2_CDK1_ST	Q9Y6I3	EPN1	P06493	CDK1	T462	K469N	469	Missense	distal	7	no	3.734	3.732	EPSD	COSMIC	3.158	Down-regulation
CMGC_CDK_CDC2_CDK1_ST	Q9Y6I3	EPN1	P06493	CDK1	T464	T464A	464	Missense	central	0	yes	3.781	0.000	EPSD	COSMIC	3.158	Loss
CMGC_CDK_CDC2_CDK1_ST	Q9Y6I3	EPN1	P06493	CDK1	T464	T467N	467	Missense	distal	3	no	3.781	3.820	EPSD	COSMIC	3.158	Up-regulation
CMGC_CDK_CDC2_CDK1_ST	Q9Y6I3	EPN1	P06493	CDK1	T464	K469N	469	Missense	distal	5	no	3.781	3.789	EPSD	COSMIC	3.158	Up-regulation
CMGC_CDK_CDC2_CDK1_ST	Q9Y6I3	EPN1	P06493	CDK1	S536	V538M	538	Missense	proximal	2	no	4.140	4.132	EPSD	COSMIC	3.158	Down-regulation
CMGC_CDK_CDC2_CDK1_ST	Q9Y6I3	EPN1	P06493	CDK1	S536	P542L	542	Missense	distal	6	no	4.140	4.084	EPSD	COSMIC	3.158	Down-regulation
CMGC_CDK_CDC2_CDK1_ST	Q92974	ARHGEF2	P06493	CDK1	S648	R642C	642	Missense	distal	-6	no	3.293	3.303	EPSD	COSMIC	3.158	Up-regulation
CMGC_CDK_CDC2_CDK1_ST	Q92974	ARHGEF2	P06493	CDK1	S648	S645F	645	Missense	distal	-3	no	3.293	3.266	EPSD	COSMIC	3.158	Down-regulation
CMGC_CDK_CDC2_CDK1_ST	Q92974	ARHGEF2	P06493	CDK1	T679	L685V	685	Missense	distal	6	no	3.161	3.187	EPSD	COSMIC	3.158	Up-regulation
CMGC_CDK_CDC2_CDK1_ST	Q92974	ARHGEF2	P06493	CDK1	S932	P933S	933	Missense	proximal	1	no	3.444	0.259	EPSD	COSMIC	3.158	Loss
CMGC_CDK_CDC2_CDK1_ST	Q92974	ARHGEF2	P06493	CDK1	S932	S932N	932	Missense	central	0	yes	3.444	0.000	EPSD	COSMIC	3.158	Loss
CMGC_CDK_CDC2_CDK1_ST	Q92974	ARHGEF2	P06493	CDK1	S932	E934K	934	Missense	proximal	2	no	3.444	3.439	EPSD	COSMIC	3.158	Down-regulation
CMGC_CDK_CDC2_CDK1_ST	Q92974	ARHGEF2	P06493	CDK1	S932	G931V	931	Missense	proximal	-1	no	3.444	3.370	EPSD	COSMIC	3.158	Down-regulation
CMGC_CDK_CDC2_CDK1_ST	Q92974	ARHGEF2	P06493	CDK1	S932	R927S	927	Missense	distal	-5	no	3.444	3.386	EPSD	COSMIC	3.158	Down-regulation
CMGC_CDK_CDC2_CDK1_ST	Q92974	ARHGEF2	P06493	CDK1	S932	E926Q	926	Missense	distal	-6	no	3.444	3.440	EPSD	COSMIC	3.158	Down-regulation
CMGC_CDK_CDC2_CDK1_ST	Q92974	ARHGEF2	P06493	CDK1	S956	S952R	952	Missense	distal	-4	no	3.517	3.451	EPSD	COSMIC	3.158	Down-regulation
CMGC_CDK_CDC2_CDK1_ST	Q92974	ARHGEF2	P06493	CDK1	S956	G951E	951	Missense	distal	-5	no	3.517	3.444	EPSD	COSMIC	3.158	Down-regulation
CMGC_CDK_CDC2_CDK1_ST	Q92974	ARHGEF2	P06493	CDK1	S956	S952T	952	Missense	distal	-4	no	3.517	3.525	EPSD	COSMIC	3.158	Up-regulation
CMGC_CDK_CDC2_CDK1_ST	Q92974	ARHGEF2	P06493	CDK1	S956	L955V	955	Missense	proximal	-1	no	3.517	3.461	EPSD	COSMIC	3.158	Down-regulation
CMGC_CDK_CDC2_CDK1_ST	Q14202	ZMYM3	P06493	CDK1	S8	P3H	3	Missense	distal	-5	no	3.266	3.297	EPSD	COSMIC	3.158	Up-regulation
CMGC_CDK_CDC2_CDK1_ST	Q14202	ZMYM3	P06493	CDK1	S51	A56S	56	Missense	distal	5	no	3.634	3.691	EPSD	COSMIC	3.158	Up-regulation
CMGC_CDK_CDC2_CDK1_ST	Q14202	ZMYM3	P06493	CDK1	T62	A56S	56	Missense	distal	-6	no	3.497	3.499	EPSD	COSMIC	3.158	Up-regulation
CMGC_CDK_CDC2_CDK1_ST	Q14202	ZMYM3	P06493	CDK1	T62	G65S	65	Missense	distal	3	no	3.497	3.619	EPSD	COSMIC;GDSC;CCLE	3.158	Up-regulation
CMGC_CDK_CDC2_CDK1_ST	Q14202	ZMYM3	P06493	CDK1	S91	P93S	93	Missense	proximal	2	no	3.201	3.199	EPSD	COSMIC	3.158	Down-regulation
CMGC_CDK_CDC2_CDK1_ST	Q14202	ZMYM3	P06493	CDK1	S154	T151P	151	Missense	distal	-3	no	3.181	3.177	EPSD	COSMIC	3.158	Down-regulation
CMGC_CDK_CDC2_CDK1_ST	Q14202	ZMYM3	P06493	CDK1	S287	R285W	285	Missense	proximal	-2	no	3.232	3.204	EPSD	COSMIC	3.158	Down-regulation
CMGC_CDK_CDC2_CDK1_ST	Q14202	ZMYM3	P06493	CDK1	S287	R283W	283	Missense	distal	-4	no	3.232	3.192	EPSD	COSMIC	3.158	Down-regulation
CMGC_CDK_CDC2_CDK1_ST	Q14202	ZMYM3	P06493	CDK1	S287	S287F	287	Missense	central	0	yes	3.232	0.000	EPSD	COSMIC	3.158	Loss
CMGC_CDK_CDC2_CDK1_ST	Q14202	ZMYM3	P06493	CDK1	S582	G585E	585	Missense	distal	3	no	3.152	3.223	EPSD	COSMIC	3.158	Gain
CMGC_CDK_CDC2_CDK1_ST	Q14202	ZMYM3	P06493	CDK1	S753	Q754P	754	Missense	proximal	1	no	0.759	3.182	EPSD	COSMIC	3.158	Gain
CMGC_CDK_CDC2_CDK1_ST	Q14202	ZMYM3	P06493	CDK1	S774	T781R	781	Missense	distal	7	no	3.322	3.327	EPSD	COSMIC	3.158	Up-regulation
CMGC_CDK_CDC2_CDK1_ST	P46060	RANGAP1	P06493	CDK1	T409	R412Q	412	Missense	distal	3	no	3.255	3.206	PhosphoSitePlus	COSMIC	3.158	Down-regulation
CMGC_CDK_CDC2_CDK1_ST	P46060	RANGAP1	P06493	CDK1	S428	P424L	424	Missense	distal	-4	no	3.161	3.018	EPSD	COSMIC	3.158	Loss
CMGC_CDK_CDC2_CDK1_ST	Q9UQ35	SRRM2	P06493	CDK1	T111	G113R	113	Missense	proximal	2	no	3.260	3.243	EPSD	COSMIC	3.158	Down-regulation
CMGC_CDK_CDC2_CDK1_ST	Q9UQ35	SRRM2	P06493	CDK1	S353	G360D	360	Missense	distal	7	no	3.215	3.201	EPSD	COSMIC	3.158	Down-regulation
CMGC_CDK_CDC2_CDK1_ST	Q9UQ35	SRRM2	P06493	CDK1	S353	S351N	351	Missense	proximal	-2	no	3.215	3.245	EPSD	COSMIC	3.158	Up-regulation
CMGC_CDK_CDC2_CDK1_ST	Q9UQ35	SRRM2	P06493	CDK1	T983	P981L	981	Missense	proximal	-2	no	3.215	3.388	EPSD	COSMIC	3.158	Up-regulation
CMGC_CDK_CDC2_CDK1_ST	Q9UQ35	SRRM2	P06493	CDK1	T983	T983A	983	Missense	central	0	yes	3.215	0.000	EPSD	COSMIC	3.158	Loss
CMGC_CDK_CDC2_CDK1_ST	Q9UQ35	SRRM2	P06493	CDK1	S994	Y996C	996	Missense	proximal	2	no	3.309	3.306	EPSD	COSMIC	3.158	Down-regulation
CMGC_CDK_CDC2_CDK1_ST	Q9UQ35	SRRM2	P06493	CDK1	S1014	P1017S	1017	Missense	distal	3	no	4.251	4.301	EPSD	COSMIC;CCLE	3.158	Up-regulation
CMGC_CDK_CDC2_CDK1_ST	Q9UQ35	SRRM2	P06493	CDK1	S1713	A1710V	1710	Missense	distal	-3	no	3.161	3.099	EPSD	COSMIC;GDSC;CCLE	3.158	Loss
CMGC_CDK_CDC2_CDK1_ST	Q9UQ35	SRRM2	P06493	CDK1	S1713	R1706K	1706	Missense	distal	-7	no	3.161	3.085	EPSD	COSMIC	3.158	Loss
CMGC_CDK_CDC2_CDK1_ST	Q9UQ35	SRRM2	P06493	CDK1	T2144	T2144R	2144	Missense	central	0	yes	3.308	0.000	EPSD	COSMIC	3.158	Loss
CMGC_CDK_CDC2_CDK1_ST	Q9UQ35	SRRM2	P06493	CDK1	T2144	S2142C	2142	Missense	proximal	-2	no	3.308	3.325	EPSD	COSMIC	3.158	Up-regulation
CMGC_CDK_CDC2_CDK1_ST	Q9UQ35	SRRM2	P06493	CDK1	S2650	S2644L	2644	Missense	distal	-6	no	3.133	3.161	EPSD	COSMIC	3.158	Gain
CMGC_CDK_CDC2_CDK1_ST	Q9UQ35	SRRM2	P06493	CDK1	T2738	P2739S	2739	Missense	proximal	1	no	3.235	0.051	EPSD	COSMIC	3.158	Loss
CMGC_CDK_CDC2_CDK1_ST	Q9UQ35	SRRM2	P06493	CDK1	S2751	R2747C	2747	Missense	distal	-4	no	3.174	3.105	EPSD	COSMIC	3.158	Loss
CMGC_CDK_CDC2_CDK1_ST	P30260	CDC27	P06493	CDK1	S237	I240L	240	Missense	distal	3	no	3.400	3.315	EPSD	COSMIC	3.158	Down-regulation
CMGC_CDK_CDC2_CDK1_ST	P30260	CDC27	P06493	CDK1	S369	T368A	368	Missense	proximal	-1	no	3.327	3.300	EPSD	COSMIC;CCLE	3.158	Down-regulation
CMGC_CDK_CDC2_CDK1_ST	P30260	CDC27	P06493	CDK1	S369	L374P	374	Missense	distal	5	no	3.327	3.142	EPSD	COSMIC	3.158	Loss
CMGC_CDK_CDC2_CDK1_ST	P30260	CDC27	P06493	CDK1	S369	P371L	371	Missense	proximal	2	no	3.327	3.348	EPSD	COSMIC	3.158	Up-regulation
CMGC_CDK_CDC2_CDK1_ST	P30260	CDC27	P06493	CDK1	T446	N453S	453	Missense	distal	7	no	3.311	3.303	EPSD;PhosphoSitePlus	COSMIC	3.158	Down-regulation
CMGC_CDK_CDC2_CDK1_ST	P30260	CDC27	P06493	CDK1	T446	E439K	439	Missense	distal	-7	no	3.311	3.266	EPSD;PhosphoSitePlus	COSMIC	3.158	Down-regulation
CMGC_CDK_CDC2_CDK1_ST	P30260	CDC27	P06493	CDK1	T446	K441I	441	Missense	distal	-5	no	3.311	3.356	EPSD;PhosphoSitePlus	COSMIC	3.158	Up-regulation
CMGC_CDK_CDC2_CDK1_ST	P30260	CDC27	P06493	CDK1	T446	S443A	443	Missense	distal	-3	no	3.311	3.353	EPSD;PhosphoSitePlus	COSMIC	3.158	Up-regulation
CMGC_CDK_CDC2_CDK1_ST	P30260	CDC27	P06493	CDK1	T446	I442V	442	Missense	distal	-4	no	3.311	3.333	EPSD;PhosphoSitePlus	COSMIC	3.158	Up-regulation
CMGC_CDK_CDC2_CDK1_ST	P30260	CDC27	P06493	CDK1	S721	N716S	716	Missense	distal	-5	no	3.284	3.236	EPSD	COSMIC	3.158	Down-regulation
CMGC_CDK_CDC2_CDK1_ST	P17302	GJA1	P06493	CDK1	S279	S279L	279	Missense	central	0	yes	3.531	0.000	EPSD	COSMIC	3.158	Loss
CMGC_CDK_CDC2_CDK1_ST	P46937	YAP1	P06493	CDK1	T143	G140W	140	Missense	distal	-3	no	3.701	3.728	EPSD;PhosphoSitePlus	COSMIC	3.158	Up-regulation
CMGC_CDK_CDC2_CDK1_ST	P46937	YAP1	P06493	CDK1	T143	P139F	139	Missense	distal	-4	no	3.701	3.606	EPSD;PhosphoSitePlus	COSMIC	3.158	Down-regulation
CMGC_CDK_CDC2_CDK1_ST	P38936	CDKN1A	P06493	CDK1	T57	D62Y	62	Missense	distal	5	no	3.807	3.837	EPSD	COSMIC	3.158	Up-regulation
CMGC_CDK_CDC2_CDK1_ST	P38936	CDKN1A	P06493	CDK1	T57	D62H	62	Missense	distal	5	no	3.807	3.774	EPSD	COSMIC	3.158	Down-regulation
CMGC_CDK_CDC2_CDK1_ST	P38936	CDKN1A	P06493	CDK1	T57	D52V	52	Missense	distal	-5	no	3.807	3.879	EPSD	COSMIC	3.158	Up-regulation
CMGC_CDK_CDC2_CDK1_ST	P38936	CDKN1A	P06493	CDK1	T57	T57R	57	Missense	central	0	yes	3.807	0.000	EPSD	COSMIC	3.158	Loss
CMGC_CDK_CDC2_CDK1_ST	P38936	CDKN1A	P06493	CDK1	S98	T97I	97	Missense	proximal	-1	no	3.213	3.439	EPSD	COSMIC	3.158	Up-regulation
CMGC_CDK_CDC2_CDK1_ST	Q32P44	EML3	P06493	CDK1	S198	L196V	196	Missense	proximal	-2	no	3.331	3.329	EPSD	COSMIC	3.158	Down-regulation
CMGC_CDK_CDC2_CDK1_ST	Q32P44	EML3	P06493	CDK1	S198	R205W	205	Missense	distal	7	no	3.331	3.338	EPSD	COSMIC	3.158	Up-regulation
CMGC_CDK_CDC2_CDK1_ST	Q32P44	EML3	P06493	CDK1	S198	P199S	199	Missense	proximal	1	no	3.331	0.146	EPSD	COSMIC	3.158	Loss
CMGC_CDK_CDC2_CDK1_ST	Q32P44	EML3	P06493	CDK1	S198	S197C	197	Missense	proximal	-1	no	3.331	3.448	EPSD	COSMIC	3.158	Up-regulation
CMGC_CDK_CDC2_CDK1_ST	Q32P44	EML3	P06493	CDK1	S198	G192R	192	Missense	distal	-6	no	3.331	3.315	EPSD	COSMIC	3.158	Down-regulation
CMGC_CDK_CDC2_CDK1_ST	Q32P44	EML3	P06493	CDK1	S198	P202R	202	Missense	distal	4	no	3.331	3.345	EPSD	COSMIC	3.158	Up-regulation
CMGC_CDK_CDC2_CDK1_ST	Q32P44	EML3	P06493	CDK1	S198	S204Y	204	Missense	distal	6	no	3.331	3.292	EPSD	COSMIC	3.158	Down-regulation
CMGC_CDK_CDC2_CDK1_ST	Q32P44	EML3	P06493	CDK1	S198	S198C	198	Missense	central	0	yes	3.331	0.000	EPSD	COSMIC	3.158	Loss
CMGC_CDK_CDC2_CDK1_ST	Q32P44	EML3	P06493	CDK1	S198	G201V	201	Missense	distal	3	no	3.331	3.353	EPSD	COSMIC	3.158	Up-regulation
CMGC_CDK_CDC2_CDK1_ST	Q32P44	EML3	P06493	CDK1	T494	D491N	491	Missense	distal	-3	no	3.545	3.546	EPSD	COSMIC	3.158	Up-regulation
CMGC_CDK_CDC2_CDK1_ST	Q32P44	EML3	P06493	CDK1	S689	V686I	686	Missense	distal	-3	no	3.210	3.190	EPSD	COSMIC;CCLE	3.158	Down-regulation
CMGC_CDK_CDC2_CDK1_ST	Q9H1A4	ANAPC1	P06493	CDK1	S202	P208S	208	Missense	distal	6	no	3.797	3.804	EPSD	COSMIC	3.158	Up-regulation
CMGC_CDK_CDC2_CDK1_ST	Q9H1A4	ANAPC1	P06493	CDK1	S202	E205Q	205	Missense	distal	3	no	3.797	3.870	EPSD	COSMIC	3.158	Up-regulation
CMGC_CDK_CDC2_CDK1_ST	Q9H1A4	ANAPC1	P06493	CDK1	T221	P222A	222	Missense	proximal	1	no	3.178	2.288	EPSD	COSMIC	3.158	Loss
CMGC_CDK_CDC2_CDK1_ST	Q9H1A4	ANAPC1	P06493	CDK1	T221	E219G	219	Missense	proximal	-2	no	3.178	3.229	EPSD	COSMIC	3.158	Up-regulation
CMGC_CDK_CDC2_CDK1_ST	Q9H1A4	ANAPC1	P06493	CDK1	T221	V224L	224	Missense	distal	3	no	3.178	3.094	EPSD	COSMIC	3.158	Loss
CMGC_CDK_CDC2_CDK1_ST	Q9H1A4	ANAPC1	P06493	CDK1	S377	I371S	371	Missense	distal	-6	no	3.324	3.302	EPSD;PhosphoSitePlus	COSMIC	3.158	Down-regulation
CMGC_CDK_CDC2_CDK1_ST	Q9H1A4	ANAPC1	P06493	CDK1	T537	T537A	537	Missense	central	0	yes	3.205	0.000	EPSD;PhosphoSitePlus	COSMIC;GDSC	3.158	Loss
CMGC_CDK_CDC2_CDK1_ST	Q9H1A4	ANAPC1	P06493	CDK1	T537	K543T	543	Missense	distal	6	no	3.205	3.226	EPSD;PhosphoSitePlus	COSMIC	3.158	Up-regulation
CMGC_CDK_CDC2_CDK1_ST	Q9H1A4	ANAPC1	P06493	CDK1	S555	D549H	549	Missense	distal	-6	no	3.424	3.425	EPSD;PhosphoSitePlus	COSMIC	3.158	Up-regulation
CMGC_CDK_CDC2_CDK1_ST	P23443	RPS6KB1	P06493	CDK1	T390	P391S	391	Missense	proximal	1	no	3.171	-0.013	EPSD	COSMIC	3.158	Loss
CMGC_CDK_CDC2_CDK1_ST	P23443	RPS6KB1	P06493	CDK1	T390	R388G	388	Missense	proximal	-2	no	3.171	3.194	EPSD	COSMIC	3.158	Up-regulation
CMGC_CDK_CDC2_CDK1_ST	P23443	RPS6KB1	P06493	CDK1	S434	I432T	432	Missense	proximal	-2	no	3.847	3.714	EPSD;PhosphoSitePlus	COSMIC	3.158	Down-regulation
CMGC_CDK_CDC2_CDK1_ST	P23443	RPS6KB1	P06493	CDK1	S434	G440A	440	Missense	distal	6	no	3.847	3.911	EPSD;PhosphoSitePlus	COSMIC	3.158	Up-regulation
CMGC_CDK_CDC2_CDK1_ST	P23443	RPS6KB1	P06493	CDK1	S434	R436Q	436	Missense	proximal	2	no	3.847	3.843	EPSD;PhosphoSitePlus	COSMIC	3.158	Down-regulation
CMGC_CDK_CDC2_CDK1_ST	P23443	RPS6KB1	P06493	CDK1	S434	E429Q	429	Missense	distal	-5	no	3.847	3.819	EPSD;PhosphoSitePlus	COSMIC	3.158	Down-regulation
CMGC_CDK_CDC2_CDK1_ST	Q8IZD2	KMT2E	P06493	CDK1	S531	S536L	536	Missense	distal	5	no	3.033	3.246	EPSD	COSMIC	3.158	Gain
CMGC_CDK_CDC2_CDK1_ST	Q8IZD2	KMT2E	P06493	CDK1	T904	P905S	905	Missense	proximal	1	no	3.351	0.166	EPSD	COSMIC;GDSC;CCLE	3.158	Loss
CMGC_CDK_CDC2_CDK1_ST	Q8IZD2	KMT2E	P06493	CDK1	T1088	S1090L	1090	Missense	proximal	2	no	3.506	3.528	EPSD	COSMIC	3.158	Up-regulation
CMGC_CDK_CDC2_CDK1_ST	Q8IZD2	KMT2E	P06493	CDK1	T1147	Q1149E	1149	Missense	proximal	2	no	3.525	3.532	EPSD	COSMIC	3.158	Up-regulation
CMGC_CDK_CDC2_CDK1_ST	Q8IZD2	KMT2E	P06493	CDK1	T1147	P1148L	1148	Missense	proximal	1	no	3.525	-0.161	EPSD	COSMIC	3.158	Loss
CMGC_CDK_CDC2_CDK1_ST	Q8IZD2	KMT2E	P06493	CDK1	S1285	C1287Y	1287	Missense	proximal	2	no	3.260	3.263	EPSD	COSMIC	3.158	Up-regulation
CMGC_CDK_CDC2_CDK1_ST	Q8IZD2	KMT2E	P06493	CDK1	S1466	L1465V	1465	Missense	proximal	-1	no	3.210	3.154	EPSD	COSMIC	3.158	Loss
CMGC_CDK_CDC2_CDK1_ST	Q8IZD2	KMT2E	P06493	CDK1	S1466	G1463D	1463	Missense	distal	-3	no	3.210	3.247	EPSD	COSMIC	3.158	Up-regulation
CMGC_CDK_CDC2_CDK1_ST	Q8IZD2	KMT2E	P06493	CDK1	S1466	P1469R	1469	Missense	distal	3	no	3.210	3.331	EPSD	COSMIC	3.158	Up-regulation
CMGC_CDK_CDC2_CDK1_ST	Q8IZD2	KMT2E	P06493	CDK1	S1466	P1467L	1467	Missense	proximal	1	no	3.210	-0.476	EPSD	COSMIC	3.158	Loss
CMGC_CDK_CDC2_CDK1_ST	Q8IZD2	KMT2E	P06493	CDK1	S1466	S1471T	1471	Missense	distal	5	no	3.210	3.216	EPSD	COSMIC	3.158	Up-regulation
CMGC_CDK_CDC2_CDK1_ST	Q8IZD2	KMT2E	P06493	CDK1	S1466	K1468M	1468	Missense	proximal	2	no	3.210	3.213	EPSD	COSMIC	3.158	Up-regulation
CMGC_CDK_CDC2_CDK1_ST	P12270	TPR	P06493	CDK1	T653	V659A	659	Missense	distal	6	no	3.119	3.167	EPSD	COSMIC	3.158	Gain
CMGC_CDK_CDC2_CDK1_ST	Q7Z3J3	RGPD4	P06493	CDK1	S1487	P1484H	1484	Missense	distal	-3	no	3.270	3.254	EPSD	COSMIC	3.158	Down-regulation
CMGC_CDK_CDC2_CDK1_ST	Q7Z3J3	RGPD4	P06493	CDK1	S1743	G1748E	1748	Missense	distal	5	no	3.302	3.199	EPSD	COSMIC	3.158	Down-regulation
CMGC_CDK_CDC2_CDK1_ST	Q7Z3J3	RGPD4	P06493	CDK1	S1743	E1745K	1745	Missense	proximal	2	no	3.302	3.297	EPSD	COSMIC	3.158	Down-regulation
CMGC_CDK_CDC2_CDK1_ST	Q9GZM8	NDEL1	P06493	CDK1	S242	G240S	240	Missense	proximal	-2	no	3.162	3.072	EPSD;PhosphoSitePlus	COSMIC	3.158	Loss
CMGC_CDK_CDC2_CDK1_ST	Q9GZM8	NDEL1	P06493	CDK1	T245	G240S	240	Missense	distal	-5	no	3.397	3.271	PhosphoSitePlus;EPSD	COSMIC	3.158	Down-regulation
CMGC_CDK_CDC2_CDK1_ST	Q16659	MAPK6	P06493	CDK1	S7	L8P	8	Missense	proximal	1	no	-0.349	3.337	EPSD	COSMIC	3.158	Gain
CMGC_CDK_CDC2_CDK1_ST	Q16659	MAPK6	P06493	CDK1	S688	Q694H	694	Missense	distal	6	no	3.314	3.312	PhosphoSitePlus;EPSD	COSMIC	3.158	Down-regulation
CMGC_CDK_CDC2_CDK1_ST	Q16659	MAPK6	P06493	CDK1	S705	P706L	706	Missense	proximal	1	no	3.186	-0.500	EPSD;PhosphoSitePlus	COSMIC	3.158	Loss
CMGC_CDK_CDC2_CDK1_ST	Q13428	TCOF1	P06493	CDK1	S233	S227L	227	Missense	distal	-6	no	3.648	3.676	EPSD	COSMIC;GDSC;CCLE	3.158	Up-regulation
CMGC_CDK_CDC2_CDK1_ST	Q13428	TCOF1	P06493	CDK1	S233	T230I	230	Missense	distal	-3	no	3.648	3.603	EPSD	COSMIC	3.158	Down-regulation
CMGC_CDK_CDC2_CDK1_ST	Q13428	TCOF1	P06493	CDK1	S503	G501W	501	Missense	proximal	-2	no	3.578	3.528	EPSD	COSMIC	3.158	Down-regulation
CMGC_CDK_CDC2_CDK1_ST	Q13428	TCOF1	P06493	CDK1	S503	G501R	501	Missense	proximal	-2	no	3.578	3.556	EPSD	COSMIC	3.158	Down-regulation
CMGC_CDK_CDC2_CDK1_ST	Q13428	TCOF1	P06493	CDK1	S823	P830L	830	Missense	distal	7	no	3.188	3.216	EPSD	COSMIC	3.158	Up-regulation
CMGC_CDK_CDC2_CDK1_ST	Q13428	TCOF1	P06493	CDK1	T1175	E1180V	1180	Missense	distal	5	no	3.147	3.217	EPSD	COSMIC	3.158	Gain
CMGC_CDK_CDC2_CDK1_ST	Q13428	TCOF1	P06493	CDK1	T1175	T1179A	1179	Missense	distal	4	no	3.147	3.199	EPSD	COSMIC	3.158	Gain
CMGC_CDK_CDC2_CDK1_ST	Q13428	TCOF1	P06493	CDK1	T1270	P1271L	1271	Missense	proximal	1	no	3.403	-0.283	EPSD	COSMIC	3.158	Loss
CMGC_CDK_CDC2_CDK1_ST	Q13428	TCOF1	P06493	CDK1	T1270	S1267N	1267	Missense	distal	-3	no	3.403	3.386	EPSD	COSMIC	3.158	Down-regulation
CMGC_CDK_CDC2_CDK1_ST	Q01581	HMGCS1	P06493	CDK1	T471	R468Q	468	Missense	distal	-3	no	3.222	3.245	EPSD	COSMIC;GDSC;CCLE	3.158	Up-regulation
CMGC_CDK_CDC2_CDK1_ST	Q01581	HMGCS1	P06493	CDK1	T471	D478N	478	Missense	distal	7	no	3.222	3.217	EPSD	COSMIC;GDSC;CCLE	3.158	Down-regulation
CMGC_CDK_CDC2_CDK1_ST	Q01581	HMGCS1	P06493	CDK1	T471	L477F	477	Missense	distal	6	no	3.222	3.234	EPSD	COSMIC;GDSC;CCLE	3.158	Up-regulation
CMGC_CDK_CDC2_CDK1_ST	Q96GX5	MASTL	P06493	CDK1	S453	P454F	454	Missense	proximal	1	no	3.169	-0.717	EPSD	COSMIC	3.158	Loss
CMGC_CDK_CDC2_CDK1_ST	Q96GX5	MASTL	P06493	CDK1	T710	Q709H	709	Missense	proximal	-1	no	3.401	3.436	EPSD	COSMIC	3.158	Up-regulation
CMGC_CDK_CDC2_CDK1_ST	Q96GX5	MASTL	P06493	CDK1	T710	I714V	714	Missense	distal	4	no	3.401	3.420	EPSD	COSMIC	3.158	Up-regulation
CMGC_CDK_CDC2_CDK1_ST	Q96GX5	MASTL	P06493	CDK1	T718	T722S	722	Missense	distal	4	no	3.397	3.389	EPSD	COSMIC	3.158	Down-regulation
CMGC_CDK_CDC2_CDK1_ST	Q96GX5	MASTL	P06493	CDK1	T718	P723L	723	Missense	distal	5	no	3.397	3.582	EPSD	COSMIC	3.158	Up-regulation
CMGC_CDK_CDC2_CDK1_ST	Q96GX5	MASTL	P06493	CDK1	T718	I714V	714	Missense	distal	-4	no	3.397	3.419	EPSD	COSMIC	3.158	Up-regulation
CMGC_CDK_CDC2_CDK1_ST	Q96GX5	MASTL	P06493	CDK1	T718	P723Q	723	Missense	distal	5	no	3.397	3.383	EPSD	COSMIC;CCLE	3.158	Down-regulation
CMGC_CDK_CDC2_CDK1_ST	Q96GX5	MASTL	P06493	CDK1	T722	R728T	728	Missense	distal	6	no	3.459	3.455	EPSD	COSMIC	3.158	Down-regulation
CMGC_CDK_CDC2_CDK1_ST	Q96GX5	MASTL	P06493	CDK1	T722	P723L	723	Missense	proximal	1	no	3.459	-0.228	EPSD	COSMIC	3.158	Loss
CMGC_CDK_CDC2_CDK1_ST	Q96GX5	MASTL	P06493	CDK1	T722	G729R	729	Missense	distal	7	no	3.459	3.439	EPSD	COSMIC	3.158	Down-regulation
CMGC_CDK_CDC2_CDK1_ST	Q96GX5	MASTL	P06493	CDK1	T722	P723Q	723	Missense	proximal	1	no	3.459	1.036	EPSD	COSMIC;CCLE	3.158	Loss
CMGC_CDK_CDC2_CDK1_ST	Q14493	SLBP	P06493	CDK1	T238	Y235H	235	Missense	distal	-3	no	3.325	3.341	EPSD	COSMIC	3.158	Up-regulation
CMGC_CDK_CDC2_CDK1_ST	Q14493	SLBP	P06493	CDK1	T238	P239H	239	Missense	proximal	1	no	3.325	0.640	EPSD	COSMIC	3.158	Loss
CMGC_CDK_CDC2_CDK1_ST	P50570	DNM2	P06493	CDK1	S116	L122F	122	Missense	distal	6	no	3.426	3.438	EPSD	COSMIC	3.158	Up-regulation
CMGC_CDK_CDC2_CDK1_ST	P50570	DNM2	P06493	CDK1	S116	T109M	109	Missense	distal	-7	no	3.426	3.338	EPSD	COSMIC	3.158	Down-regulation
CMGC_CDK_CDC2_CDK1_ST	P50570	DNM2	P06493	CDK1	S126	L122F	122	Missense	distal	-4	no	3.421	3.469	EPSD	COSMIC	3.158	Up-regulation
CMGC_CDK_CDC2_CDK1_ST	P50570	DNM2	P06493	CDK1	T280	L281P	281	Missense	proximal	1	no	-0.493	3.193	EPSD	COSMIC	3.158	Gain
CMGC_CDK_CDC2_CDK1_ST	P50570	DNM2	P06493	CDK1	T353	L354P	354	Missense	proximal	1	no	-0.337	3.349	EPSD	COSMIC	3.158	Gain
CMGC_CDK_CDC2_CDK1_ST	P50570	DNM2	P06493	CDK1	T404	G397L	397	Missense	distal	-7	no	3.627	3.584	EPSD	COSMIC	3.158	Down-regulation
CMGC_CDK_CDC2_CDK1_ST	P50570	DNM2	P06493	CDK1	T404	A408P	408	Missense	distal	4	no	3.627	3.570	EPSD	COSMIC	3.158	Down-regulation
CMGC_CDK_CDC2_CDK1_ST	O94761	RECQL4	P06493	CDK1	S89	P94L	94	Missense	distal	5	no	3.021	3.206	EPSD;PhosphoSitePlus	COSMIC	3.158	Gain
CMGC_CDK_CDC2_CDK1_ST	O94761	RECQL4	P06493	CDK1	T93	R96Q	96	Missense	distal	3	no	3.723	3.675	EPSD	COSMIC	3.158	Down-regulation
CMGC_CDK_CDC2_CDK1_ST	O94761	RECQL4	P06493	CDK1	T93	K88N	88	Missense	distal	-5	no	3.723	3.687	EPSD	COSMIC	3.158	Down-regulation
CMGC_CDK_CDC2_CDK1_ST	O94761	RECQL4	P06493	CDK1	T93	P94L	94	Missense	proximal	1	no	3.723	0.037	EPSD	COSMIC	3.158	Loss
CMGC_CDK_CDC2_CDK1_ST	O94761	RECQL4	P06493	CDK1	T93	G100E	100	Missense	distal	7	no	3.723	3.710	EPSD	COSMIC	3.158	Down-regulation
CMGC_CDK_CDC2_CDK1_ST	O94761	RECQL4	P06493	CDK1	S323	G321R	321	Missense	proximal	-2	no	3.327	3.304	EPSD	COSMIC	3.158	Down-regulation
CMGC_CDK_CDC2_CDK1_ST	O94761	RECQL4	P06493	CDK1	S323	P324S	324	Missense	proximal	1	no	3.327	0.142	EPSD	COSMIC	3.158	Loss
CMGC_CDK_CDC2_CDK1_ST	O94761	RECQL4	P06493	CDK1	S323	P324L	324	Missense	proximal	1	no	3.327	-0.360	EPSD	COSMIC	3.158	Loss
CMGC_CDK_CDC2_CDK1_ST	Q8WUF5	PPP1R13L	P06493	CDK1	T95	A88V	88	Missense	distal	-7	no	3.180	3.029	EPSD	COSMIC	3.158	Loss
CMGC_CDK_CDC2_CDK1_ST	Q8WUF5	PPP1R13L	P06493	CDK1	S280	F275V	275	Missense	distal	-5	no	3.158	3.165	EPSD	COSMIC	3.158	Up-regulation
CMGC_CDK_CDC2_CDK1_ST	Q8WUF5	PPP1R13L	P06493	CDK1	S280	P281L	281	Missense	proximal	1	no	3.158	-0.528	EPSD	COSMIC	3.158	Loss
CMGC_CDK_CDC2_CDK1_ST	Q8WUF5	PPP1R13L	P06493	CDK1	S280	V274I	274	Missense	distal	-6	no	3.158	3.162	EPSD	COSMIC	3.158	Up-regulation
CMGC_CDK_CDC2_CDK1_ST	Q8WUF5	PPP1R13L	P06493	CDK1	S280	L283V	283	Missense	distal	3	no	3.158	3.241	EPSD	COSMIC;GDSC;CCLE	3.158	Up-regulation
CMGC_CDK_CDC2_CDK1_ST	Q8WUF5	PPP1R13L	P06493	CDK1	S316	L309P	309	Missense	distal	-7	no	3.014	3.175	EPSD	COSMIC	3.158	Gain
CMGC_CDK_CDC2_CDK1_ST	Q8WUF5	PPP1R13L	P06493	CDK1	S616	A623T	623	Missense	distal	7	no	3.554	3.568	EPSD	COSMIC	3.158	Up-regulation
CMGC_CDK_CDC2_CDK1_ST	Q8WUF5	PPP1R13L	P06493	CDK1	S616	S609F	609	Missense	distal	-7	no	3.554	3.408	EPSD	COSMIC	3.158	Down-regulation
CMGC_CDK_CDC2_CDK1_ST	Q8WUF5	PPP1R13L	P06493	CDK1	S616	A623S	623	Missense	distal	7	no	3.554	3.564	EPSD	COSMIC	3.158	Up-regulation
CMGC_CDK_CDC2_CDK1_ST	Q8WUF5	PPP1R13L	P06493	CDK1	S616	P617S	617	Missense	proximal	1	no	3.554	0.369	EPSD	COSMIC	3.158	Loss
CMGC_CDK_CDC2_CDK1_ST	Q8WUF5	PPP1R13L	P06493	CDK1	S616	R618L	618	Missense	proximal	2	no	3.554	3.569	EPSD	COSMIC	3.158	Up-regulation
CMGC_CDK_CDC2_CDK1_ST	Q8WUF5	PPP1R13L	P06493	CDK1	S616	A623V	623	Missense	distal	7	no	3.554	3.588	EPSD	COSMIC	3.158	Up-regulation
CMGC_CDK_CDC2_CDK1_ST	Q8WUF5	PPP1R13L	P06493	CDK1	S616	R622H	622	Missense	distal	6	no	3.554	3.535	EPSD	COSMIC	3.158	Down-regulation
CMGC_CDK_CDC2_CDK1_ST	A6NKT7	RGPD3	P06493	CDK1	T897	P892L	892	Missense	distal	-5	no	3.041	3.162	EPSD	COSMIC	3.158	Gain
CMGC_CDK_CDC2_CDK1_ST	A6NKT7	RGPD3	P06493	CDK1	T1153	P1154S	1154	Missense	proximal	1	no	3.362	0.177	EPSD	COSMIC	3.158	Loss
CMGC_CDK_CDC2_CDK1_ST	A6NKT7	RGPD3	P06493	CDK1	S1301	L1302P	1302	Missense	proximal	1	no	-0.440	3.246	EPSD	COSMIC	3.158	Gain
CMGC_CDK_CDC2_CDK1_ST	A6NKT7	RGPD3	P06493	CDK1	S1305	L1302P	1302	Missense	distal	-3	no	3.427	3.459	EPSD	COSMIC	3.158	Up-regulation
CMGC_CDK_CDC2_CDK1_ST	A6NKT7	RGPD3	P06493	CDK1	S1305	S1312R	1312	Missense	distal	7	no	3.427	3.436	EPSD	COSMIC	3.158	Up-regulation
CMGC_CDK_CDC2_CDK1_ST	A6NKT7	RGPD3	P06493	CDK1	S1305	P1306L	1306	Missense	proximal	1	no	3.427	-0.259	EPSD	COSMIC	3.158	Loss
CMGC_CDK_CDC2_CDK1_ST	A6NKT7	RGPD3	P06493	CDK1	T1412	R1410T	1410	Missense	proximal	-2	no	3.322	3.216	EPSD	COSMIC	3.158	Down-regulation
CMGC_CDK_CDC2_CDK1_ST	A6NKT7	RGPD3	P06493	CDK1	T1475	E1469D	1469	Missense	distal	-6	no	3.386	3.387	EPSD	COSMIC	3.158	Up-regulation
CMGC_CDK_CDC2_CDK1_ST	A6NKT7	RGPD3	P06493	CDK1	S1535	V1534G	1534	Missense	proximal	-1	no	3.084	3.158	EPSD	COSMIC	3.158	Gain
CMGC_CDK_CDC2_CDK1_ST	Q9UPP1	PHF8	P06493	CDK1	S175	P174S	174	Missense	proximal	-1	no	3.293	3.241	EPSD	COSMIC	3.158	Down-regulation
CMGC_CDK_CDC2_CDK1_ST	Q9UPP1	PHF8	P06493	CDK1	S175	V180L	180	Missense	distal	5	no	3.293	3.356	EPSD	COSMIC	3.158	Up-regulation
CMGC_CDK_CDC2_CDK1_ST	Q9UPP1	PHF8	P06493	CDK1	S175	S175L	175	Missense	central	0	yes	3.293	0.000	EPSD	COSMIC	3.158	Loss
CMGC_CDK_CDC2_CDK1_ST	Q9UPP1	PHF8	P06493	CDK1	T359	T359M	359	Missense	central	0	yes	3.531	0.000	EPSD	COSMIC	3.158	Loss
CMGC_CDK_CDC2_CDK1_ST	Q9UPP1	PHF8	P06493	CDK1	T359	D362Y	362	Missense	distal	3	no	3.531	3.525	EPSD	COSMIC	3.158	Down-regulation
CMGC_CDK_CDC2_CDK1_ST	Q9UPP1	PHF8	P06493	CDK1	S880	P878Q	878	Missense	proximal	-2	no	3.385	3.524	EPSD	COSMIC	3.158	Up-regulation
CMGC_CDK_CDC2_CDK1_ST	Q9UPP1	PHF8	P06493	CDK1	S880	R884C	884	Missense	distal	4	no	3.385	3.321	EPSD	COSMIC	3.158	Down-regulation
CMGC_CDK_CDC2_CDK1_ST	Q9UPP1	PHF8	P06493	CDK1	S880	P887Q	887	Missense	distal	7	no	3.385	3.387	EPSD	COSMIC	3.158	Up-regulation
CMGC_CDK_CDC2_CDK1_ST	Q9UPP1	PHF8	P06493	CDK1	S880	A877S	877	Missense	distal	-3	no	3.385	3.342	EPSD	COSMIC	3.158	Down-regulation
CMGC_CDK_CDC2_CDK1_ST	Q9UPP1	PHF8	P06493	CDK1	S880	R884L	884	Missense	distal	4	no	3.385	3.248	EPSD	COSMIC;CCLE	3.158	Down-regulation
CMGC_CDK_CDC2_CDK1_ST	Q12778	FOXO1	P06493	CDK1	S394	S393Y	393	Missense	proximal	-1	no	3.109	3.258	EPSD	COSMIC	3.158	Gain
CMGC_CDK_CDC2_CDK1_ST	Q12778	FOXO1	P06493	CDK1	S432	P438H	438	Missense	distal	6	no	3.415	3.409	EPSD	COSMIC	3.158	Down-regulation
CMGC_CDK_CDC2_CDK1_ST	Q12778	FOXO1	P06493	CDK1	S432	S432N	432	Missense	central	0	yes	3.415	0.000	EPSD	COSMIC	3.158	Loss
CMGC_CDK_CDC2_CDK1_ST	Q12778	FOXO1	P06493	CDK1	S432	I439V	439	Missense	distal	7	no	3.415	3.412	EPSD	COSMIC	3.158	Down-regulation
CMGC_CDK_CDC2_CDK1_ST	Q12778	FOXO1	P06493	CDK1	S432	G427V	427	Missense	distal	-5	no	3.415	3.405	EPSD	COSMIC	3.158	Down-regulation
CMGC_CDK_CDC2_CDK1_ST	Q86WB0	ZC3HC1	P06493	CDK1	S24	P29L	29	Missense	distal	5	no	3.407	3.591	EPSD	COSMIC	3.158	Up-regulation
CMGC_CDK_CDC2_CDK1_ST	Q86WB0	ZC3HC1	P06493	CDK1	T28	R33L	33	Missense	distal	5	no	2.975	3.198	EPSD	COSMIC	3.158	Gain
CMGC_CDK_CDC2_CDK1_ST	Q86WB0	ZC3HC1	P06493	CDK1	S62	E66K	66	Missense	distal	4	no	3.312	3.343	EPSD	COSMIC	3.158	Up-regulation
CMGC_CDK_CDC2_CDK1_ST	Q86WB0	ZC3HC1	P06493	CDK1	S98	A103E	103	Missense	distal	5	no	3.590	3.727	EPSD	COSMIC	3.158	Up-regulation
CMGC_CDK_CDC2_CDK1_ST	P62136	PPP1CA	P06493	CDK1	T320	P321T	321	Missense	proximal	1	no	3.640	1.207	PhosphoSitePlus	COSMIC	3.158	Loss
CMGC_CDK_CDC2_CDK1_ST	P62136	PPP1CA	P06493	CDK1	T320	P322S	322	Missense	proximal	2	no	3.640	3.638	PhosphoSitePlus	COSMIC	3.158	Down-regulation
CMGC_CDK_CDC2_CDK1_ST	P62136	PPP1CA	P06493	CDK1	T320	R323H	323	Missense	distal	3	no	3.640	3.548	PhosphoSitePlus	COSMIC	3.158	Down-regulation
CMGC_CDK_CDC2_CDK1_ST	P62136	PPP1CA	P06493	CDK1	T320	A326T	326	Missense	distal	6	no	3.640	3.632	PhosphoSitePlus	COSMIC	3.158	Down-regulation
CMGC_CDK_CDC2_CDK1_ST	P62136	PPP1CA	P06493	CDK1	T320	G315W	315	Missense	distal	-5	no	3.640	3.597	PhosphoSitePlus	COSMIC	3.158	Down-regulation
CMGC_CDK_CDC2_CDK1_ST	Q15910	EZH2	P06493	CDK1	T261	I264T	264	Missense	distal	3	no	3.123	3.185	EPSD	COSMIC	3.158	Gain
CMGC_CDK_CDC2_CDK1_ST	Q15910	EZH2	P06493	CDK1	T261	G254A	254	Missense	distal	-7	no	3.123	3.308	EPSD	COSMIC	3.158	Gain
CMGC_CDK_CDC2_CDK1_ST	Q15910	EZH2	P06493	CDK1	T261	I264R	264	Missense	distal	3	no	3.123	3.290	EPSD	COSMIC	3.158	Gain
CMGC_CDK_CDC2_CDK1_ST	Q15910	EZH2	P06493	CDK1	T487	A482T	482	Missense	distal	-5	no	3.376	3.398	PhosphoSitePlus;EPSD	COSMIC	3.158	Up-regulation
CMGC_CDK_CDC2_CDK1_ST	Q15910	EZH2	P06493	CDK1	T487	P488S	488	Missense	proximal	1	no	3.376	0.192	PhosphoSitePlus;EPSD	COSMIC	3.158	Loss
CMGC_CDK_CDC2_CDK1_ST	Q15910	EZH2	P06493	CDK1	T487	R494S	494	Missense	distal	7	no	3.376	3.368	PhosphoSitePlus;EPSD	COSMIC	3.158	Down-regulation
CMGC_CDK_CDC2_CDK1_ST	Q15910	EZH2	P06493	CDK1	T487	R494K	494	Missense	distal	7	no	3.376	3.378	PhosphoSitePlus;EPSD	COSMIC	3.158	Up-regulation
CMGC_CDK_CDC2_CDK1_ST	Q15910	EZH2	P06493	CDK1	T487	P481S	481	Missense	distal	-6	no	3.376	3.375	PhosphoSitePlus;EPSD	COSMIC	3.158	Down-regulation
CMGC_CDK_CDC2_CDK1_ST	Q15910	EZH2	P06493	CDK1	T487	P488A	488	Missense	proximal	1	no	3.376	2.487	PhosphoSitePlus;EPSD	COSMIC	3.158	Loss
CMGC_CDK_CDC2_CDK1_ST	Q15910	EZH2	P06493	CDK1	T487	K491R	491	Missense	distal	4	no	3.376	3.407	PhosphoSitePlus;EPSD	COSMIC	3.158	Up-regulation
CMGC_CDK_CDC2_CDK1_ST	O95235	KIF20A	P06493	CDK1	S405	L406P	406	Missense	proximal	1	no	-0.501	3.185	EPSD	COSMIC	3.158	Gain
CMGC_CDK_CDC2_CDK1_ST	O95235	KIF20A	P06493	CDK1	S867	R874C	874	Missense	distal	7	no	3.385	3.392	PhosphoSitePlus;EPSD	COSMIC;GDSC;CCLE	3.158	Up-regulation
CMGC_CDK_CDC2_CDK1_ST	O95235	KIF20A	P06493	CDK1	S867	R871W	871	Missense	distal	4	no	3.385	3.312	PhosphoSitePlus;EPSD	COSMIC	3.158	Down-regulation
CMGC_CDK_CDC2_CDK1_ST	O95235	KIF20A	P06493	CDK1	S867	R871Q	871	Missense	distal	4	no	3.385	3.367	PhosphoSitePlus;EPSD	COSMIC	3.158	Down-regulation
CMGC_CDK_CDC2_CDK1_ST	P30304	CDC25A	P06493	CDK1	S40	G37W	37	Missense	distal	-3	no	4.045	4.073	EPSD	COSMIC	3.158	Up-regulation
CMGC_CDK_CDC2_CDK1_ST	P30304	CDC25A	P06493	CDK1	S261	R255G	255	Missense	distal	-6	no	3.152	3.168	EPSD	COSMIC	3.158	Gain
CMGC_CDK_CDC2_CDK1_ST	P30304	CDC25A	P06493	CDK1	S261	L264V	264	Missense	distal	3	no	3.152	3.235	EPSD	COSMIC	3.158	Gain
CMGC_CDK_CDC2_CDK1_ST	P30304	CDC25A	P06493	CDK1	S321	P322L	322	Missense	proximal	1	no	3.190	-0.496	EPSD	COSMIC	3.158	Loss
CMGC_CDK_CDC2_CDK1_ST	P30304	CDC25A	P06493	CDK1	S321	S320Y	320	Missense	proximal	-1	no	3.190	3.339	EPSD	COSMIC	3.158	Up-regulation
CMGC_CDK_CDC2_CDK1_ST	P30304	CDC25A	P06493	CDK1	S361	V368A	368	Missense	distal	7	no	3.369	3.335	EPSD	COSMIC	3.158	Down-regulation
CMGC_CDK_CDC2_CDK1_ST	P30304	CDC25A	P06493	CDK1	S361	S367F	367	Missense	distal	6	no	3.369	3.318	EPSD	COSMIC	3.158	Down-regulation
CMGC_CDK_CDC2_CDK1_ST	P30304	CDC25A	P06493	CDK1	S361	S367P	367	Missense	distal	6	no	3.369	3.362	EPSD	COSMIC	3.158	Down-regulation
CMGC_CDK_CDC2_CDK1_ST	Q38SD2	LRRK1	P06493	CDK1	S784	G787S	787	Missense	distal	3	no	3.076	3.198	EPSD	COSMIC	3.158	Gain
CMGC_CDK_CDC2_CDK1_ST	Q15398	DLGAP5	P06493	CDK1	T338	L337V	337	Missense	proximal	-1	no	3.161	3.105	EPSD	COSMIC	3.158	Loss
CMGC_CDK_CDC2_CDK1_ST	Q15398	DLGAP5	P06493	CDK1	T344	L337V	337	Missense	distal	-7	no	3.371	3.447	EPSD	COSMIC	3.158	Up-regulation
CMGC_CDK_CDC2_CDK1_ST	Q15398	DLGAP5	P06493	CDK1	T639	G638E	638	Missense	proximal	-1	no	3.313	3.186	EPSD;PhosphoSitePlus	COSMIC	3.158	Down-regulation
CMGC_CDK_CDC2_CDK1_ST	Q15398	DLGAP5	P06493	CDK1	T639	P640H	640	Missense	proximal	1	no	3.313	0.628	EPSD;PhosphoSitePlus	COSMIC	3.158	Loss
CMGC_CDK_CDC2_CDK1_ST	Q15398	DLGAP5	P06493	CDK1	T639	Q635E	635	Missense	distal	-4	no	3.313	3.301	EPSD;PhosphoSitePlus	COSMIC	3.158	Down-regulation
CMGC_CDK_CDC2_CDK1_ST	Q15398	DLGAP5	P06493	CDK1	S767	E769K	769	Missense	proximal	2	no	3.386	3.381	EPSD	COSMIC	3.158	Down-regulation
CMGC_CDK_CDC2_CDK1_ST	P52948	NUP98	P06493	CDK1	S511	S507I	507	Missense	distal	-4	no	3.220	3.077	EPSD	COSMIC	3.158	Loss
CMGC_CDK_CDC2_CDK1_ST	P52948	NUP98	P06493	CDK1	S511	N506Y	506	Missense	distal	-5	no	3.220	3.253	EPSD	COSMIC	3.158	Up-regulation
CMGC_CDK_CDC2_CDK1_ST	P52948	NUP98	P06493	CDK1	S511	Y510H	510	Missense	proximal	-1	no	3.220	3.157	EPSD	COSMIC	3.158	Loss
CMGC_CDK_CDC2_CDK1_ST	P52948	NUP98	P06493	CDK1	S511	Y510F	510	Missense	proximal	-1	no	3.220	3.224	EPSD	COSMIC	3.158	Up-regulation
CMGC_CDK_CDC2_CDK1_ST	P52948	NUP98	P06493	CDK1	T553	R555H	555	Missense	proximal	2	no	3.429	3.433	EPSD	COSMIC	3.158	Up-regulation
CMGC_CDK_CDC2_CDK1_ST	P52948	NUP98	P06493	CDK1	T553	R555P	555	Missense	proximal	2	no	3.429	3.423	EPSD	COSMIC	3.158	Down-regulation
CMGC_CDK_CDC2_CDK1_ST	P52948	NUP98	P06493	CDK1	T553	L552R	552	Missense	proximal	-1	no	3.429	3.289	EPSD	COSMIC	3.158	Down-regulation
CMGC_CDK_CDC2_CDK1_ST	P52948	NUP98	P06493	CDK1	T553	P556L	556	Missense	distal	3	no	3.429	3.296	EPSD	COSMIC	3.158	Down-regulation
CMGC_CDK_CDC2_CDK1_ST	P52948	NUP98	P06493	CDK1	T553	T553K	553	Missense	central	0	yes	3.429	0.000	EPSD	COSMIC	3.158	Loss
CMGC_CDK_CDC2_CDK1_ST	P52948	NUP98	P06493	CDK1	S839	A844S	844	Missense	distal	5	no	3.422	3.479	EPSD	COSMIC	3.158	Up-regulation
CMGC_CDK_CDC2_CDK1_ST	P52948	NUP98	P06493	CDK1	S839	R842C	842	Missense	distal	3	no	3.422	3.302	EPSD	COSMIC	3.158	Down-regulation
CMGC_CDK_CDC2_CDK1_ST	P52948	NUP98	P06493	CDK1	S839	R842H	842	Missense	distal	3	no	3.422	3.329	EPSD	COSMIC	3.158	Down-regulation
CMGC_CDK_CDC2_CDK1_ST	P52948	NUP98	P06493	CDK1	S839	R834S	834	Missense	distal	-5	no	3.422	3.364	EPSD	COSMIC;GDSC;CCLE	3.158	Down-regulation
CMGC_CDK_CDC2_CDK1_ST	P52948	NUP98	P06493	CDK1	S934	P929S	929	Missense	distal	-5	no	3.204	3.181	EPSD	COSMIC	3.158	Down-regulation
CMGC_CDK_CDC2_CDK1_ST	P52948	NUP98	P06493	CDK1	S934	Q939K	939	Missense	distal	5	no	3.204	3.222	EPSD	COSMIC	3.158	Up-regulation
CMGC_CDK_CDC2_CDK1_ST	P52948	NUP98	P06493	CDK1	S934	S932N	932	Missense	proximal	-2	no	3.204	3.233	EPSD	COSMIC	3.158	Up-regulation
CMGC_CDK_CDC2_CDK1_ST	P52948	NUP98	P06493	CDK1	S934	S932I	932	Missense	proximal	-2	no	3.204	3.298	EPSD	COSMIC	3.158	Up-regulation
CMGC_CDK_CDC2_CDK1_ST	P52948	NUP98	P06493	CDK1	S934	A927T	927	Missense	distal	-7	no	3.204	3.197	EPSD	COSMIC	3.158	Down-regulation
CMGC_CDK_CDC2_CDK1_ST	P52948	NUP98	P06493	CDK1	S934	Q931H	931	Missense	distal	-3	no	3.204	3.191	EPSD	COSMIC	3.158	Down-regulation
CMGC_CDK_CDC2_CDK1_ST	P52948	NUP98	P06493	CDK1	S1099	S1099N	1099	Missense	central	0	yes	3.402	0.000	EPSD	COSMIC	3.158	Loss
CMGC_CDK_CDC2_CDK1_ST	P52948	NUP98	P06493	CDK1	S1099	P1105R	1105	Missense	distal	6	no	3.402	3.416	EPSD	COSMIC	3.158	Up-regulation
CMGC_CDK_CDC2_CDK1_ST	P52948	NUP98	P06493	CDK1	S1099	S1099C	1099	Missense	central	0	yes	3.402	0.000	EPSD	COSMIC	3.158	Loss
CMGC_CDK_CDC2_CDK1_ST	P52948	NUP98	P06493	CDK1	S1099	V1104A	1104	Missense	distal	5	no	3.402	3.195	EPSD	COSMIC	3.158	Down-regulation
CMGC_CDK_CDC2_CDK1_ST	P52948	NUP98	P06493	CDK1	S1099	F1095C	1095	Missense	distal	-4	no	3.402	3.413	EPSD	COSMIC	3.158	Up-regulation
CMGC_CDK_CDC2_CDK1_ST	P52948	NUP98	P06493	CDK1	S1099	S1093F	1093	Missense	distal	-6	no	3.402	3.426	EPSD	COSMIC	3.158	Up-regulation
CMGC_CDK_CDC2_CDK1_ST	P52948	NUP98	P06493	CDK1	S1099	A1101V	1101	Missense	proximal	2	no	3.402	3.425	EPSD	COSMIC	3.158	Up-regulation
CMGC_CDK_CDC2_CDK1_ST	P52948	NUP98	P06493	CDK1	T1217	L1223F	1223	Missense	distal	6	no	4.124	4.136	EPSD	COSMIC	3.158	Up-regulation
CMGC_CDK_CDC2_CDK1_ST	P52948	NUP98	P06493	CDK1	T1217	M1212I	1212	Missense	distal	-5	no	4.124	4.198	EPSD	COSMIC	3.158	Up-regulation
CMGC_CDK_CDC2_CDK1_ST	P52948	NUP98	P06493	CDK1	T1315	T1315R	1315	Missense	central	0	yes	3.159	0.000	EPSD	COSMIC	3.158	Loss
CMGC_CDK_CDC2_CDK1_ST	P52948	NUP98	P06493	CDK1	T1315	S1311C	1311	Missense	distal	-4	no	3.159	3.023	EPSD	COSMIC	3.158	Loss
CMGC_CDK_CDC2_CDK1_ST	P52948	NUP98	P06493	CDK1	T1315	T1315I	1315	Missense	central	0	yes	3.159	0.000	EPSD	COSMIC	3.158	Loss
CMGC_CDK_CDC2_CDK1_ST	Q12888	TP53BP1	P06493	CDK1	T334	S330C	330	Missense	distal	-4	no	3.504	3.368	EPSD	COSMIC	3.158	Down-regulation
CMGC_CDK_CDC2_CDK1_ST	Q12888	TP53BP1	P06493	CDK1	T334	S330F	330	Missense	distal	-4	no	3.504	3.357	EPSD	COSMIC	3.158	Down-regulation
CMGC_CDK_CDC2_CDK1_ST	Q12888	TP53BP1	P06493	CDK1	S727	D726Y	726	Missense	proximal	-1	no	3.111	3.174	EPSD	COSMIC	3.158	Gain
CMGC_CDK_CDC2_CDK1_ST	Q12888	TP53BP1	P06493	CDK1	S1028	S1028I	1028	Missense	central	0	yes	3.299	0.000	EPSD	COSMIC	3.158	Loss
CMGC_CDK_CDC2_CDK1_ST	Q12888	TP53BP1	P06493	CDK1	S1028	V1026A	1026	Missense	proximal	-2	no	3.299	3.134	EPSD	COSMIC	3.158	Loss
CMGC_CDK_CDC2_CDK1_ST	Q12888	TP53BP1	P06493	CDK1	S1028	A1027G	1027	Missense	proximal	-1	no	3.299	3.573	EPSD	COSMIC	3.158	Up-regulation
CMGC_CDK_CDC2_CDK1_ST	Q12888	TP53BP1	P06493	CDK1	S1101	S1094N	1094	Missense	distal	-7	no	3.297	3.238	EPSD	COSMIC	3.158	Down-regulation
CMGC_CDK_CDC2_CDK1_ST	Q12888	TP53BP1	P06493	CDK1	S1101	S1094C	1094	Missense	distal	-7	no	3.297	3.183	EPSD	COSMIC	3.158	Down-regulation
CMGC_CDK_CDC2_CDK1_ST	Q12888	TP53BP1	P06493	CDK1	S1101	S1101F	1101	Missense	central	0	yes	3.297	0.000	EPSD	COSMIC	3.158	Loss
CMGC_CDK_CDC2_CDK1_ST	Q12888	TP53BP1	P06493	CDK1	S1288	T1285S	1285	Missense	distal	-3	no	3.678	3.673	EPSD	COSMIC	3.158	Down-regulation
CMGC_CDK_CDC2_CDK1_ST	Q12888	TP53BP1	P06493	CDK1	S1288	Q1291E	1291	Missense	distal	3	no	3.678	3.605	EPSD	COSMIC	3.158	Down-regulation
CMGC_CDK_CDC2_CDK1_ST	Q12888	TP53BP1	P06493	CDK1	T1394	P1392S	1392	Missense	proximal	-2	no	3.128	3.254	EPSD	COSMIC	3.158	Gain
CMGC_CDK_CDC2_CDK1_ST	Q12888	TP53BP1	P06493	CDK1	T1638	S1643G	1643	Missense	distal	5	no	3.152	3.334	EPSD	COSMIC	3.158	Gain
CMGC_CDK_CDC2_CDK1_ST	Q12888	TP53BP1	P06493	CDK1	S1678	E1676Q	1676	Missense	proximal	-2	no	3.993	3.968	PhosphoSitePlus;EPSD	COSMIC	3.158	Down-regulation
CMGC_CDK_CDC2_CDK1_ST	Q12888	TP53BP1	P06493	CDK1	S1678	P1679S	1679	Missense	proximal	1	no	3.993	0.809	PhosphoSitePlus;EPSD	COSMIC	3.158	Loss
CMGC_CDK_CDC2_CDK1_ST	Q9BYG3	NIFK	P06493	CDK1	T223	K226N	226	Missense	distal	3	no	3.227	3.179	EPSD	COSMIC	3.158	Down-regulation
CMGC_CDK_CDC2_CDK1_ST	Q9BYG3	NIFK	P06493	CDK1	T223	P224S	224	Missense	proximal	1	no	3.227	0.042	EPSD	COSMIC	3.158	Loss
CMGC_CDK_CDC2_CDK1_ST	O15350	TP73	P06493	CDK1	T167	Q162R	162	Missense	distal	-5	no	3.416	3.448	EPSD	COSMIC	3.158	Up-regulation
CMGC_CDK_CDC2_CDK1_ST	O15350	TP73	P06493	CDK1	T167	A174G	174	Missense	distal	7	no	3.416	3.454	EPSD	COSMIC	3.158	Up-regulation
CMGC_CDK_CDC2_CDK1_ST	O15350	TP73	P06493	CDK1	T167	S166F	166	Missense	proximal	-1	no	3.416	3.569	EPSD	COSMIC	3.158	Up-regulation
CMGC_CDK_CDC2_CDK1_ST	O15350	TP73	P06493	CDK1	T167	P171L	171	Missense	distal	4	no	3.416	3.293	EPSD	COSMIC	3.158	Down-regulation
CMGC_CDK_CDC2_CDK1_ST	O15350	TP73	P06493	CDK1	S333	S333R	333	Missense	central	0	yes	3.491	0.000	EPSD	COSMIC	3.158	Loss
CMGC_CDK_CDC2_CDK1_ST	O15350	TP73	P06493	CDK1	S333	P335L	335	Missense	proximal	2	no	3.491	3.511	EPSD	COSMIC;GDSC;CCLE	3.158	Up-regulation
CMGC_CDK_CDC2_CDK1_ST	O15350	TP73	P06493	CDK1	S412	M414I	414	Missense	proximal	2	no	3.757	3.770	EPSD	COSMIC	3.158	Up-regulation
CMGC_CDK_CDC2_CDK1_ST	O15350	TP73	P06493	CDK1	S412	S412L	412	Missense	central	0	yes	3.757	0.000	EPSD	COSMIC	3.158	Loss
CMGC_CDK_CDC2_CDK1_ST	O15350	TP73	P06493	CDK1	S412	S406P	406	Missense	distal	-6	no	3.757	3.758	EPSD	COSMIC	3.158	Up-regulation
CMGC_CDK_CDC2_CDK1_ST	P63279	UBE2I	P06493	CDK1	S70	S71P	71	Missense	proximal	1	no	0.308	3.493	EPSD	COSMIC	3.158	Gain
CMGC_CDK_CDC2_CDK1_ST	Q09666	AHNAK	P06493	CDK1	S41	Q39H	39	Missense	proximal	-2	no	3.152	3.160	EPSD	COSMIC	3.158	Gain
CMGC_CDK_CDC2_CDK1_ST	Q09666	AHNAK	P06493	CDK1	S41	T38A	38	Missense	distal	-3	no	3.152	3.189	EPSD	COSMIC	3.158	Gain
CMGC_CDK_CDC2_CDK1_ST	Q09666	AHNAK	P06493	CDK1	S41	A43V	43	Missense	proximal	2	no	3.152	3.174	EPSD	COSMIC	3.158	Gain
CMGC_CDK_CDC2_CDK1_ST	Q09666	AHNAK	P06493	CDK1	S93	D91N	91	Missense	proximal	-2	no	3.165	3.176	EPSD	COSMIC	3.158	Up-regulation
CMGC_CDK_CDC2_CDK1_ST	Q09666	AHNAK	P06493	CDK1	S216	S216P	216	Missense	central	0	yes	3.517	0.000	EPSD	COSMIC	3.158	Loss
CMGC_CDK_CDC2_CDK1_ST	Q09666	AHNAK	P06493	CDK1	S216	S210L	210	Missense	distal	-6	no	3.517	3.545	EPSD	COSMIC	3.158	Up-regulation
CMGC_CDK_CDC2_CDK1_ST	Q09666	AHNAK	P06493	CDK1	S216	P209S	209	Missense	distal	-7	no	3.517	3.557	EPSD	COSMIC	3.158	Up-regulation
CMGC_CDK_CDC2_CDK1_ST	Q09666	AHNAK	P06493	CDK1	T324	G328V	328	Missense	distal	4	no	3.806	3.838	EPSD	COSMIC	3.158	Up-regulation
CMGC_CDK_CDC2_CDK1_ST	Q09666	AHNAK	P06493	CDK1	T324	E321A	321	Missense	distal	-3	no	3.806	3.875	EPSD	COSMIC	3.158	Up-regulation
CMGC_CDK_CDC2_CDK1_ST	Q09666	AHNAK	P06493	CDK1	T324	R330G	330	Missense	distal	6	no	3.806	3.747	EPSD	COSMIC	3.158	Down-regulation
CMGC_CDK_CDC2_CDK1_ST	Q09666	AHNAK	P06493	CDK1	T490	G485D	485	Missense	distal	-5	no	4.009	3.928	EPSD	COSMIC	3.158	Down-regulation
CMGC_CDK_CDC2_CDK1_ST	Q09666	AHNAK	P06493	CDK1	T694	D689N	689	Missense	distal	-5	no	3.212	3.215	EPSD	COSMIC	3.158	Up-regulation
CMGC_CDK_CDC2_CDK1_ST	Q09666	AHNAK	P06493	CDK1	T694	V692I	692	Missense	proximal	-2	no	3.212	3.260	EPSD	COSMIC	3.158	Up-regulation
CMGC_CDK_CDC2_CDK1_ST	Q09666	AHNAK	P06493	CDK1	T1192	T1192I	1192	Missense	central	0	yes	3.414	0.000	EPSD	COSMIC	3.158	Loss
CMGC_CDK_CDC2_CDK1_ST	Q09666	AHNAK	P06493	CDK1	T2832	P2833A	2833	Missense	proximal	1	no	3.419	2.530	EPSD	COSMIC	3.158	Loss
CMGC_CDK_CDC2_CDK1_ST	Q09666	AHNAK	P06493	CDK1	S3412	M3417I	3417	Missense	distal	5	no	3.740	3.835	EPSD	COSMIC	3.158	Up-regulation
CMGC_CDK_CDC2_CDK1_ST	Q09666	AHNAK	P06493	CDK1	T3716	G3723R	3723	Missense	distal	7	no	3.654	3.635	EPSD	COSMIC	3.158	Down-regulation
CMGC_CDK_CDC2_CDK1_ST	Q09666	AHNAK	P06493	CDK1	T4100	D4104G	4104	Missense	distal	4	no	3.736	3.673	EPSD	COSMIC	3.158	Down-regulation
CMGC_CDK_CDC2_CDK1_ST	Q09666	AHNAK	P06493	CDK1	T4100	P4101S	4101	Missense	proximal	1	no	3.736	0.551	EPSD	COSMIC	3.158	Loss
CMGC_CDK_CDC2_CDK1_ST	Q09666	AHNAK	P06493	CDK1	T4100	D4097G	4097	Missense	distal	-3	no	3.736	3.699	EPSD	COSMIC;GDSC;CCLE	3.158	Down-regulation
CMGC_CDK_CDC2_CDK1_ST	Q09666	AHNAK	P06493	CDK1	T4430	V4433D	4433	Missense	distal	3	no	3.386	3.417	EPSD	COSMIC	3.158	Up-regulation
CMGC_CDK_CDC2_CDK1_ST	Q09666	AHNAK	P06493	CDK1	S4516	V4512A	4512	Missense	distal	-4	no	3.413	3.507	EPSD	COSMIC	3.158	Up-regulation
CMGC_CDK_CDC2_CDK1_ST	Q09666	AHNAK	P06493	CDK1	S4516	P4510L	4510	Missense	distal	-6	no	3.413	3.439	EPSD	COSMIC	3.158	Up-regulation
CMGC_CDK_CDC2_CDK1_ST	Q09666	AHNAK	P06493	CDK1	S4516	D4523A	4523	Missense	distal	7	no	3.413	3.389	EPSD	COSMIC	3.158	Down-regulation
CMGC_CDK_CDC2_CDK1_ST	Q09666	AHNAK	P06493	CDK1	T4766	V4771I	4771	Missense	distal	5	no	3.639	3.653	EPSD	COSMIC	3.158	Up-regulation
CMGC_CDK_CDC2_CDK1_ST	Q09666	AHNAK	P06493	CDK1	S4986	S4986I	4986	Missense	central	0	yes	3.325	0.000	EPSD	COSMIC	3.158	Loss
CMGC_CDK_CDC2_CDK1_ST	Q09666	AHNAK	P06493	CDK1	S4986	I4991T	4991	Missense	distal	5	no	3.325	3.167	EPSD	COSMIC	3.158	Down-regulation
CMGC_CDK_CDC2_CDK1_ST	Q09666	AHNAK	P06493	CDK1	S5110	A5104T	5104	Missense	distal	-6	no	3.499	3.500	EPSD	COSMIC	3.158	Up-regulation
CMGC_CDK_CDC2_CDK1_ST	Q09666	AHNAK	P06493	CDK1	S5731	G5730D	5730	Missense	proximal	-1	no	3.540	3.405	EPSD	COSMIC	3.158	Down-regulation
CMGC_CDK_CDC2_CDK1_ST	Q09666	AHNAK	P06493	CDK1	S5763	S5763L	5763	Missense	central	0	yes	3.373	0.000	PhosphoSitePlus	COSMIC	3.158	Loss
CMGC_CDK_CDC2_CDK1_ST	Q09666	AHNAK	P06493	CDK1	S5763	F5768L	5768	Missense	distal	5	no	3.373	3.420	PhosphoSitePlus	COSMIC	3.158	Up-regulation
CMGC_CDK_CDC2_CDK1_ST	Q09666	AHNAK	P06493	CDK1	T5794	S5790C	5790	Missense	distal	-4	no	3.321	3.185	EPSD	COSMIC	3.158	Down-regulation
CMGC_CDK_CDC2_CDK1_ST	Q09666	AHNAK	P06493	CDK1	T5794	L5799P	5799	Missense	distal	5	no	3.321	3.136	EPSD	COSMIC	3.158	Loss
CMGC_CDK_CDC2_CDK1_ST	P55211	CASP9	P06493	CDK1	T125	T125P	125	Missense	central	0	yes	3.655	0.000	PhosphoSitePlus	COSMIC	3.158	Loss
CMGC_CDK_CDC2_CDK1_ST	P55211	CASP9	P06493	CDK1	S302	E297G	297	Missense	distal	-5	no	3.188	3.261	EPSD	COSMIC	3.158	Up-regulation
CMGC_CDK_CDC2_CDK1_ST	P55211	CASP9	P06493	CDK1	S302	G295V	295	Missense	distal	-7	no	3.188	3.222	EPSD	COSMIC	3.158	Up-regulation
CMGC_CDK_CDC2_CDK1_ST	Q13042	CDC16	P06493	CDK1	S560	P561L	561	Missense	proximal	1	no	3.693	0.007	EPSD;PhosphoSitePlus	COSMIC	3.158	Loss
CMGC_CDK_CDC2_CDK1_ST	Q13042	CDC16	P06493	CDK1	T581	T581M	581	Missense	central	0	yes	3.329	0.000	EPSD;PhosphoSitePlus	COSMIC	3.158	Loss
CMGC_CDK_CDC2_CDK1_ST	Q13042	CDC16	P06493	CDK1	T581	R587S	587	Missense	distal	6	no	3.329	3.323	EPSD;PhosphoSitePlus	COSMIC	3.158	Down-regulation
CMGC_CDK_CDC2_CDK1_ST	Q13042	CDC16	P06493	CDK1	T581	R587W	587	Missense	distal	6	no	3.329	3.291	EPSD;PhosphoSitePlus	COSMIC	3.158	Down-regulation
CMGC_CDK_CDC2_CDK1_ST	Q13042	CDC16	P06493	CDK1	T589	R587S	587	Missense	proximal	-2	no	3.383	3.316	EPSD	COSMIC	3.158	Down-regulation
CMGC_CDK_CDC2_CDK1_ST	Q13042	CDC16	P06493	CDK1	T589	R587W	587	Missense	proximal	-2	no	3.383	3.355	EPSD	COSMIC	3.158	Down-regulation
CMGC_CDK_CDC2_CDK1_ST	O94782	USP1	P06493	CDK1	S16	G11R	11	Missense	distal	-5	no	3.187	3.119	EPSD	COSMIC;GDSC;CCLE	3.158	Loss
CMGC_CDK_CDC2_CDK1_ST	O94782	USP1	P06493	CDK1	S16	K19N	19	Missense	distal	3	no	3.187	3.139	EPSD	COSMIC	3.158	Loss
CMGC_CDK_CDC2_CDK1_ST	O94782	USP1	P06493	CDK1	S16	S18L	18	Missense	proximal	2	no	3.187	3.210	EPSD	COSMIC	3.158	Up-regulation
CMGC_CDK_CDC2_CDK1_ST	O94782	USP1	P06493	CDK1	S313	P314H	314	Missense	proximal	1	no	3.488	0.804	PhosphoSitePlus	COSMIC	3.158	Loss
CMGC_CDK_CDC2_CDK1_ST	O94782	USP1	P06493	CDK1	S313	P315L	315	Missense	proximal	2	no	3.488	3.508	PhosphoSitePlus	COSMIC	3.158	Up-regulation
CMGC_CDK_CDC2_CDK1_ST	O94782	USP1	P06493	CDK1	S313	P319S	319	Missense	distal	6	no	3.488	3.495	PhosphoSitePlus	COSMIC	3.158	Up-regulation
CMGC_CDK_CDC2_CDK1_ST	O94782	USP1	P06493	CDK1	S398	N401H	401	Missense	distal	3	no	3.359	3.332	EPSD	COSMIC	3.158	Down-regulation
CMGC_CDK_CDC2_CDK1_ST	O94782	USP1	P06493	CDK1	T404	V406I	406	Missense	proximal	2	no	3.499	3.503	EPSD	COSMIC;GDSC;CCLE	3.158	Up-regulation
CMGC_CDK_CDC2_CDK1_ST	Q92574	TSC1	P06493	CDK1	S205	H206P	206	Missense	proximal	1	no	0.773	3.457	EPSD	COSMIC	3.158	Gain
CMGC_CDK_CDC2_CDK1_ST	Q92574	TSC1	P06493	CDK1	T357	T356A	356	Missense	proximal	-1	no	3.356	3.329	EPSD	COSMIC	3.158	Down-regulation
CMGC_CDK_CDC2_CDK1_ST	Q92574	TSC1	P06493	CDK1	T357	T360N	360	Missense	distal	3	no	3.356	3.395	EPSD	COSMIC	3.158	Up-regulation
CMGC_CDK_CDC2_CDK1_ST	Q92574	TSC1	P06493	CDK1	T357	M351V	351	Missense	distal	-6	no	3.356	3.365	EPSD	COSMIC	3.158	Up-regulation
CMGC_CDK_CDC2_CDK1_ST	Q92574	TSC1	P06493	CDK1	T357	T356I	356	Missense	proximal	-1	no	3.356	3.581	EPSD	COSMIC	3.158	Up-regulation
CMGC_CDK_CDC2_CDK1_ST	Q92574	TSC1	P06493	CDK1	T390	P397S	397	Missense	distal	7	no	3.706	3.704	EPSD	COSMIC	3.158	Down-regulation
CMGC_CDK_CDC2_CDK1_ST	Q92574	TSC1	P06493	CDK1	T390	P391S	391	Missense	proximal	1	no	3.706	0.522	EPSD	COSMIC	3.158	Loss
CMGC_CDK_CDC2_CDK1_ST	Q92574	TSC1	P06493	CDK1	T390	P387L	387	Missense	distal	-3	no	3.706	3.675	EPSD	COSMIC	3.158	Down-regulation
CMGC_CDK_CDC2_CDK1_ST	Q92574	TSC1	P06493	CDK1	T390	S394Y	394	Missense	distal	4	no	3.706	3.637	EPSD	COSMIC	3.158	Down-regulation
CMGC_CDK_CDC2_CDK1_ST	Q92574	TSC1	P06493	CDK1	T390	P391T	391	Missense	proximal	1	no	3.706	1.273	EPSD	COSMIC	3.158	Loss
CMGC_CDK_CDC2_CDK1_ST	Q92574	TSC1	P06493	CDK1	T390	L388P	388	Missense	proximal	-2	no	3.706	3.533	EPSD	COSMIC;CCLE	3.158	Down-regulation
CMGC_CDK_CDC2_CDK1_ST	Q92574	TSC1	P06493	CDK1	T417	K421E	421	Missense	distal	4	no	3.283	3.252	EPSD;PhosphoSitePlus	COSMIC	3.158	Down-regulation
CMGC_CDK_CDC2_CDK1_ST	Q92574	TSC1	P06493	CDK1	T417	E422D	422	Missense	distal	5	no	3.283	3.291	EPSD;PhosphoSitePlus	COSMIC	3.158	Up-regulation
CMGC_CDK_CDC2_CDK1_ST	Q92574	TSC1	P06493	CDK1	T417	E422V	422	Missense	distal	5	no	3.283	3.353	EPSD;PhosphoSitePlus	COSMIC	3.158	Up-regulation
CMGC_CDK_CDC2_CDK1_ST	Q92574	TSC1	P06493	CDK1	T417	R424K	424	Missense	distal	7	no	3.283	3.284	EPSD;PhosphoSitePlus	COSMIC	3.158	Up-regulation
CMGC_CDK_CDC2_CDK1_ST	Q92574	TSC1	P06493	CDK1	T417	E423D	423	Missense	distal	6	no	3.283	3.281	EPSD;PhosphoSitePlus	COSMIC	3.158	Down-regulation
CMGC_CDK_CDC2_CDK1_ST	Q92574	TSC1	P06493	CDK1	S565	C572Y	572	Missense	distal	7	no	3.423	3.424	EPSD	COSMIC;GDSC;CCLE	3.158	Up-regulation
CMGC_CDK_CDC2_CDK1_ST	Q92574	TSC1	P06493	CDK1	S565	G560S	560	Missense	distal	-5	no	3.423	3.297	EPSD	COSMIC	3.158	Down-regulation
CMGC_CDK_CDC2_CDK1_ST	Q92574	TSC1	P06493	CDK1	S565	P566H	566	Missense	proximal	1	no	3.423	0.739	EPSD	COSMIC	3.158	Loss
CMGC_CDK_CDC2_CDK1_ST	Q92574	TSC1	P06493	CDK1	S565	A567V	567	Missense	proximal	2	no	3.423	3.446	EPSD	COSMIC	3.158	Up-regulation
CMGC_CDK_CDC2_CDK1_ST	Q92574	TSC1	P06493	CDK1	S565	E564K	564	Missense	proximal	-1	no	3.423	3.462	EPSD	COSMIC	3.158	Up-regulation
CMGC_CDK_CDC2_CDK1_ST	Q92574	TSC1	P06493	CDK1	T582	L576R	576	Missense	distal	-6	no	3.782	3.761	EPSD	COSMIC	3.158	Down-regulation
CMGC_CDK_CDC2_CDK1_ST	Q92574	TSC1	P06493	CDK1	T582	K587R	587	Missense	distal	5	no	3.782	3.740	EPSD	COSMIC	3.158	Down-regulation
CMGC_CDK_CDC2_CDK1_ST	Q92574	TSC1	P06493	CDK1	T582	P585A	585	Missense	distal	3	no	3.782	3.885	EPSD	COSMIC	3.158	Up-regulation
CMGC_CDK_CDC2_CDK1_ST	Q92574	TSC1	P06493	CDK1	T582	E577K	577	Missense	distal	-5	no	3.782	3.812	EPSD	COSMIC	3.158	Up-regulation
CMGC_CDK_CDC2_CDK1_ST	Q92574	TSC1	P06493	CDK1	T582	P583S	583	Missense	proximal	1	no	3.782	0.597	EPSD	COSMIC	3.158	Loss
CMGC_CDK_CDC2_CDK1_ST	Q92574	TSC1	P06493	CDK1	T582	E577D	577	Missense	distal	-5	no	3.782	3.773	EPSD	COSMIC	3.158	Down-regulation
CMGC_CDK_CDC2_CDK1_ST	Q92574	TSC1	P06493	CDK1	S584	P590L	590	Missense	distal	6	no	3.520	3.463	EPSD;PhosphoSitePlus	COSMIC	3.158	Down-regulation
CMGC_CDK_CDC2_CDK1_ST	Q92574	TSC1	P06493	CDK1	S584	P590S	590	Missense	distal	6	no	3.520	3.527	EPSD;PhosphoSitePlus	COSMIC	3.158	Up-regulation
CMGC_CDK_CDC2_CDK1_ST	Q92574	TSC1	P06493	CDK1	S584	P590Q	590	Missense	distal	6	no	3.520	3.516	EPSD;PhosphoSitePlus	COSMIC	3.158	Down-regulation
CMGC_CDK_CDC2_CDK1_ST	Q92574	TSC1	P06493	CDK1	S584	K587R	587	Missense	distal	3	no	3.520	3.537	EPSD;PhosphoSitePlus	COSMIC	3.158	Up-regulation
CMGC_CDK_CDC2_CDK1_ST	Q92574	TSC1	P06493	CDK1	S584	P585A	585	Missense	proximal	1	no	3.520	2.630	EPSD;PhosphoSitePlus	COSMIC	3.158	Loss
CMGC_CDK_CDC2_CDK1_ST	Q92574	TSC1	P06493	CDK1	S584	E577K	577	Missense	distal	-7	no	3.520	3.474	EPSD;PhosphoSitePlus	COSMIC	3.158	Down-regulation
CMGC_CDK_CDC2_CDK1_ST	Q92574	TSC1	P06493	CDK1	S584	P583S	583	Missense	proximal	-1	no	3.520	3.468	EPSD;PhosphoSitePlus	COSMIC	3.158	Down-regulation
CMGC_CDK_CDC2_CDK1_ST	Q92574	TSC1	P06493	CDK1	S584	P591S	591	Missense	distal	7	no	3.520	3.517	EPSD;PhosphoSitePlus	COSMIC	3.158	Down-regulation
CMGC_CDK_CDC2_CDK1_ST	Q92574	TSC1	P06493	CDK1	S584	E577D	577	Missense	distal	-7	no	3.520	3.526	EPSD;PhosphoSitePlus	COSMIC	3.158	Up-regulation
CMGC_CDK_CDC2_CDK1_ST	Q92574	TSC1	P06493	CDK1	S644	P641L	641	Missense	distal	-3	no	3.512	3.480	EPSD	COSMIC	3.158	Down-regulation
CMGC_CDK_CDC2_CDK1_ST	Q92574	TSC1	P06493	CDK1	S644	P645S	645	Missense	proximal	1	no	3.512	0.327	EPSD	COSMIC	3.158	Loss
CMGC_CDK_CDC2_CDK1_ST	Q92574	TSC1	P06493	CDK1	S644	V648M	648	Missense	distal	4	no	3.512	3.555	EPSD	COSMIC	3.158	Up-regulation
CMGC_CDK_CDC2_CDK1_ST	Q92574	TSC1	P06493	CDK1	S644	R651K	651	Missense	distal	7	no	3.512	3.513	EPSD	COSMIC	3.158	Up-regulation
CMGC_CDK_CDC2_CDK1_ST	Q92574	TSC1	P06493	CDK1	S644	D638H	638	Missense	distal	-6	no	3.512	3.513	EPSD	COSMIC	3.158	Up-regulation
CMGC_CDK_CDC2_CDK1_ST	Q92574	TSC1	P06493	CDK1	S644	M646I	646	Missense	proximal	2	no	3.512	3.525	EPSD	COSMIC	3.158	Up-regulation
CMGC_CDK_CDC2_CDK1_ST	Q92574	TSC1	P06493	CDK1	S644	T643I	643	Missense	proximal	-1	no	3.512	3.737	EPSD	COSMIC	3.158	Up-regulation
CMGC_CDK_CDC2_CDK1_ST	Q92574	TSC1	P06493	CDK1	S682	G680D	680	Missense	proximal	-2	no	3.246	3.175	EPSD	COSMIC	3.158	Down-regulation
CMGC_CDK_CDC2_CDK1_ST	Q92574	TSC1	P06493	CDK1	S682	R689H	689	Missense	distal	7	no	3.246	3.247	EPSD	COSMIC	3.158	Up-regulation
CMGC_CDK_CDC2_CDK1_ST	Q92574	TSC1	P06493	CDK1	S682	R689C	689	Missense	distal	7	no	3.246	3.252	EPSD	COSMIC	3.158	Up-regulation
CMGC_CDK_CDC2_CDK1_ST	Q92574	TSC1	P06493	CDK1	S682	G681D	681	Missense	proximal	-1	no	3.246	3.111	EPSD	COSMIC;GDSC	3.158	Loss
CMGC_CDK_CDC2_CDK1_ST	Q92574	TSC1	P06493	CDK1	S682	F679V	679	Missense	distal	-3	no	3.246	3.254	EPSD	COSMIC	3.158	Up-regulation
CMGC_CDK_CDC2_CDK1_ST	Q92574	TSC1	P06493	CDK1	S1141	P1142L	1142	Missense	proximal	1	no	3.628	-0.058	EPSD	COSMIC	3.158	Loss
CMGC_CDK_CDC2_CDK1_ST	Q92574	TSC1	P06493	CDK1	S1141	G1137S	1137	Missense	distal	-4	no	3.628	3.766	EPSD	COSMIC	3.158	Up-regulation
CMGC_CDK_CDC2_CDK1_ST	Q92574	TSC1	P06493	CDK1	S1141	P1138L	1138	Missense	distal	-3	no	3.628	3.597	EPSD	COSMIC	3.158	Down-regulation
CMGC_CDK_CDC2_CDK1_ST	Q92574	TSC1	P06493	CDK1	T1144	P1142L	1142	Missense	proximal	-2	no	3.323	3.497	EPSD	COSMIC	3.158	Up-regulation
CMGC_CDK_CDC2_CDK1_ST	Q92574	TSC1	P06493	CDK1	T1144	G1137S	1137	Missense	distal	-7	no	3.323	3.482	EPSD	COSMIC	3.158	Up-regulation
CMGC_CDK_CDC2_CDK1_ST	Q92574	TSC1	P06493	CDK1	T1144	P1138L	1138	Missense	distal	-6	no	3.323	3.350	EPSD	COSMIC	3.158	Up-regulation
CMGC_CDK_CDC2_CDK1_ST	P47736	RAP1GAP	P06493	CDK1	S484	S490L	490	Missense	distal	6	no	3.368	3.305	PhosphoSitePlus	COSMIC	3.158	Down-regulation
CMGC_CDK_CDC2_CDK1_ST	P47736	RAP1GAP	P06493	CDK1	S484	T486M	486	Missense	proximal	2	no	3.368	3.376	PhosphoSitePlus	COSMIC	3.158	Up-regulation
CMGC_CDK_CDC2_CDK1_ST	P47736	RAP1GAP	P06493	CDK1	S484	P485S	485	Missense	proximal	1	no	3.368	0.184	PhosphoSitePlus	COSMIC	3.158	Loss
CMGC_CDK_CDC2_CDK1_ST	P47736	RAP1GAP	P06493	CDK1	S484	G482R	482	Missense	proximal	-2	no	3.368	3.346	PhosphoSitePlus	COSMIC	3.158	Down-regulation
CMGC_CDK_CDC2_CDK1_ST	P47736	RAP1GAP	P06493	CDK1	S495	R496P	496	Missense	proximal	1	no	-0.128	3.481	EPSD	COSMIC	3.158	Gain
CMGC_CDK_CDC2_CDK1_ST	Q99661	KIF2C	P06493	CDK1	T537	E541V	541	Missense	distal	4	no	3.173	3.141	PhosphoSitePlus	COSMIC	3.158	Loss
CMGC_CDK_CDC2_CDK1_ST	Q99661	KIF2C	P06493	CDK1	T537	T537I	537	Missense	central	0	yes	3.173	0.000	PhosphoSitePlus	COSMIC	3.158	Loss
CMGC_CDK_CDC2_CDK1_ST	Q99661	KIF2C	P06493	CDK1	T537	P538S	538	Missense	proximal	1	no	3.173	-0.012	PhosphoSitePlus	COSMIC	3.158	Loss
CMGC_CDK_CDC2_CDK1_ST	Q99661	KIF2C	P06493	CDK1	T537	R540S	540	Missense	distal	3	no	3.173	3.102	PhosphoSitePlus	COSMIC	3.158	Loss
CMGC_CDK_CDC2_CDK1_ST	Q99661	KIF2C	P06493	CDK1	T537	P538L	538	Missense	proximal	1	no	3.173	-0.513	PhosphoSitePlus	COSMIC	3.158	Loss
CMGC_CDK_CDC2_CDK1_ST	Q99661	KIF2C	P06493	CDK1	T537	K534N	534	Missense	distal	-3	no	3.173	3.194	PhosphoSitePlus	COSMIC	3.158	Up-regulation
CMGC_CDK_CDC2_CDK1_ST	Q99661	KIF2C	P06493	CDK1	S589	P594T	594	Missense	distal	5	no	3.234	3.212	EPSD	COSMIC	3.158	Down-regulation
CMGC_CDK_CDC2_CDK1_ST	Q99661	KIF2C	P06493	CDK1	S589	P590H	590	Missense	proximal	1	no	3.234	0.550	EPSD	COSMIC	3.158	Loss
CMGC_CDK_CDC2_CDK1_ST	Q99661	KIF2C	P06493	CDK1	S589	L588M	588	Missense	proximal	-1	no	3.234	3.121	EPSD	COSMIC;GDSC;CCLE	3.158	Loss
CMGC_CDK_CDC2_CDK1_ST	P56181	NDUFV3	P06493	CDK1	S53	Q47R	47	Missense	distal	-6	no	3.399	3.401	EPSD	COSMIC	3.158	Up-regulation
CMGC_CDK_CDC2_CDK1_ST	P56181	NDUFV3	P06493	CDK1	S53	A59V	59	Missense	distal	6	no	3.399	3.351	EPSD	COSMIC	3.158	Down-regulation
CMGC_CDK_CDC2_CDK1_ST	P56181	NDUFV3	P06493	CDK1	S105	S105L	105	Missense	central	0	yes	3.567	0.000	PhosphoSitePlus	COSMIC	3.158	Loss
CMGC_CDK_CDC2_CDK1_ST	P56181	NDUFV3	P06493	CDK1	S105	R103Q	103	Missense	proximal	-2	no	3.567	3.513	PhosphoSitePlus	COSMIC	3.158	Down-regulation
CMGC_CDK_CDC2_CDK1_ST	P56181	NDUFV3	P06493	CDK1	S105	R103W	103	Missense	proximal	-2	no	3.567	3.539	PhosphoSitePlus	COSMIC	3.158	Down-regulation
CMGC_CDK_CDC2_CDK1_ST	Q5FBB7	SGO1	P06493	CDK1	T425	E418Q	418	Missense	distal	-7	no	3.487	3.525	EPSD	COSMIC	3.158	Up-regulation
CMGC_CDK_CDC2_CDK1_ST	Q5FBB7	SGO1	P06493	CDK1	T425	E418G	418	Missense	distal	-7	no	3.487	3.396	EPSD	COSMIC	3.158	Down-regulation
CMGC_CDK_CDC2_CDK1_ST	Q5FBB7	SGO1	P06493	CDK1	S436	D443N	443	Missense	distal	7	no	3.541	3.536	EPSD	COSMIC	3.158	Down-regulation
CMGC_CDK_CDC2_CDK1_ST	Q5FBB7	SGO1	P06493	CDK1	S436	L441P	441	Missense	distal	5	no	3.541	3.357	EPSD	COSMIC	3.158	Down-regulation
CMGC_CDK_CDC2_CDK1_ST	Q5FBB7	SGO1	P06493	CDK1	S461	K466R	466	Missense	distal	5	no	3.250	3.208	EPSD	COSMIC	3.158	Down-regulation
CMGC_CDK_CDC2_CDK1_ST	Q5FBB7	SGO1	P06493	CDK1	S461	K454T	454	Missense	distal	-7	no	3.250	3.383	EPSD	COSMIC	3.158	Up-regulation
CMGC_CDK_CDC2_CDK1_ST	Q5FBB7	SGO1	P06493	CDK1	S461	R457K	457	Missense	distal	-4	no	3.250	3.203	EPSD	COSMIC	3.158	Down-regulation
CMGC_CDK_CDC2_CDK1_ST	Q01167	FOXK2	P06493	CDK1	S170	E166K	166	Missense	distal	-4	no	3.505	3.452	EPSD	COSMIC	3.158	Down-regulation
CMGC_CDK_CDC2_CDK1_ST	Q01167	FOXK2	P06493	CDK1	S170	Q176L	176	Missense	distal	6	no	3.505	3.453	EPSD	COSMIC	3.158	Down-regulation
CMGC_CDK_CDC2_CDK1_ST	Q01167	FOXK2	P06493	CDK1	S199	S199F	199	Missense	central	0	yes	3.231	0.000	EPSD	COSMIC	3.158	Loss
CMGC_CDK_CDC2_CDK1_ST	Q01167	FOXK2	P06493	CDK1	S199	P198S	198	Missense	proximal	-1	no	3.231	3.179	EPSD	COSMIC	3.158	Down-regulation
CMGC_CDK_CDC2_CDK1_ST	Q01167	FOXK2	P06493	CDK1	S213	S220A	220	Missense	distal	7	no	3.683	3.672	EPSD	COSMIC	3.158	Down-regulation
CMGC_CDK_CDC2_CDK1_ST	Q01167	FOXK2	P06493	CDK1	S213	G216K	216	Missense	distal	3	no	3.683	3.858	EPSD	COSMIC	3.158	Up-regulation
CMGC_CDK_CDC2_CDK1_ST	Q01167	FOXK2	P06493	CDK1	T648	T648M	648	Missense	central	0	yes	3.485	0.000	EPSD	COSMIC	3.158	Loss
CMGC_CDK_CDC2_CDK1_ST	Q01167	FOXK2	P06493	CDK1	T648	V653I	653	Missense	distal	5	no	3.485	3.499	EPSD	COSMIC;CCLE	3.158	Up-regulation
CMGC_CDK_CDC2_CDK1_ST	Q9NZJ0	DTL	P06493	CDK1	T464	T471I	471	Missense	distal	7	no	3.142	3.164	PhosphoSitePlus	COSMIC	3.158	Gain
CMGC_CDK_CDC2_CDK1_ST	Q9NZJ0	DTL	P06493	CDK1	S623	P624L	624	Missense	proximal	1	no	3.844	0.158	EPSD	COSMIC	3.158	Loss
CMGC_CDK_CDC2_CDK1_ST	Q9NZJ0	DTL	P06493	CDK1	S623	P622S	622	Missense	proximal	-1	no	3.844	3.792	EPSD	COSMIC;CCLE	3.158	Down-regulation
CMGC_CDK_CDC2_CDK1_ST	Q9NZJ0	DTL	P06493	CDK1	S623	P627Q	627	Missense	distal	4	no	3.844	3.840	EPSD	COSMIC	3.158	Down-regulation
CMGC_CDK_CDC2_CDK1_ST	Q9NZJ0	DTL	P06493	CDK1	S623	P627S	627	Missense	distal	4	no	3.844	3.841	EPSD	COSMIC	3.158	Down-regulation
CMGC_CDK_CDC2_CDK1_ST	Q9NZJ0	DTL	P06493	CDK1	S626	P624L	624	Missense	proximal	-2	no	3.153	3.326	EPSD	COSMIC	3.158	Gain
CMGC_CDK_CDC2_CDK1_ST	Q9NZJ0	DTL	P06493	CDK1	S626	P622S	622	Missense	distal	-4	no	3.153	3.204	EPSD	COSMIC;CCLE	3.158	Gain
CMGC_CDK_CDC2_CDK1_ST	Q9NZJ0	DTL	P06493	CDK1	T702	T702M	702	Missense	central	0	yes	3.191	0.000	EPSD	COSMIC	3.158	Loss
CMGC_CDK_CDC2_CDK1_ST	P49915	GMPS	P06493	CDK1	T616	R622Q	622	Missense	distal	6	no	3.545	3.528	EPSD	COSMIC	3.158	Down-regulation
CMGC_CDK_CDC2_CDK1_ST	P49915	GMPS	P06493	CDK1	T616	R622W	622	Missense	distal	6	no	3.545	3.507	EPSD	COSMIC	3.158	Down-regulation
CMGC_CDK_CDC2_CDK1_ST	P49915	GMPS	P06493	CDK1	T616	V613L	613	Missense	distal	-3	no	3.545	3.533	EPSD	COSMIC;GDSC;CCLE	3.158	Down-regulation
CMGC_CDK_CDC2_CDK1_ST	P49915	GMPS	P06493	CDK1	T616	P612L	612	Missense	distal	-4	no	3.545	3.402	EPSD	COSMIC	3.158	Down-regulation
CMGC_CDK_CDC2_CDK1_ST	P49915	GMPS	P06493	CDK1	T652	I649V	649	Missense	distal	-3	no	3.196	3.217	EPSD	COSMIC;CCLE	3.158	Up-regulation
CMGC_CDK_CDC2_CDK1_ST	O00418	EEF2K	P06493	CDK1	S18	G22R	22	Missense	distal	4	no	3.093	3.218	EPSD	COSMIC	3.158	Gain
CMGC_CDK_CDC2_CDK1_ST	O00418	EEF2K	P06493	CDK1	S359	T364N	364	Missense	distal	5	no	3.244	3.278	PhosphoSitePlus	COSMIC	3.158	Up-regulation
CMGC_CDK_CDC2_CDK1_ST	O00418	EEF2K	P06493	CDK1	S359	E355K	355	Missense	distal	-4	no	3.244	3.190	PhosphoSitePlus	COSMIC	3.158	Down-regulation
CMGC_CDK_CDC2_CDK1_ST	O00418	EEF2K	P06493	CDK1	T401	S398C	398	Missense	distal	-3	no	3.389	3.374	EPSD	COSMIC	3.158	Down-regulation
CMGC_CDK_CDC2_CDK1_ST	O00418	EEF2K	P06493	CDK1	T401	S399L	399	Missense	proximal	-2	no	3.389	3.436	EPSD	COSMIC	3.158	Up-regulation
CMGC_CDK_CDC2_CDK1_ST	O00418	EEF2K	P06493	CDK1	T401	P394L	394	Missense	distal	-7	no	3.389	3.228	EPSD	COSMIC;GDSC;CCLE	3.158	Down-regulation
CMGC_CDK_CDC2_CDK1_ST	O00418	EEF2K	P06493	CDK1	T401	P394S	394	Missense	distal	-7	no	3.389	3.429	EPSD	COSMIC	3.158	Up-regulation
CMGC_CDK_CDC2_CDK1_ST	Q9BXS6	NUSAP1	P06493	CDK1	S135	A131T	131	Missense	distal	-4	no	3.211	3.247	EPSD	COSMIC	3.158	Up-regulation
CMGC_CDK_CDC2_CDK1_ST	Q9BXS6	NUSAP1	P06493	CDK1	T244	R249C	249	Missense	distal	5	no	3.338	3.446	EPSD	COSMIC	3.158	Up-regulation
CMGC_CDK_CDC2_CDK1_ST	Q9BXS6	NUSAP1	P06493	CDK1	T244	R250C	250	Missense	distal	6	no	3.338	3.301	EPSD	COSMIC	3.158	Down-regulation
CMGC_CDK_CDC2_CDK1_ST	Q9BXS6	NUSAP1	P06493	CDK1	S251	Q252P	252	Missense	proximal	1	no	1.082	3.505	EPSD	COSMIC;GDSC;CCLE	3.158	Gain
CMGC_CDK_CDC2_CDK1_ST	Q9BXS6	NUSAP1	P06493	CDK1	T300	S305T	305	Missense	distal	5	no	3.540	3.547	PhosphoSitePlus;EPSD	COSMIC	3.158	Up-regulation
CMGC_CDK_CDC2_CDK1_ST	Q9BXS6	NUSAP1	P06493	CDK1	S305	V308M	308	Missense	distal	3	no	3.098	3.159	EPSD	COSMIC	3.158	Gain
CMGC_CDK_CDC2_CDK1_ST	P33316	DUT	P06493	CDK1	S88	T95S	95	Missense	distal	7	no	3.452	3.449	EPSD	COSMIC	3.158	Down-regulation
CMGC_CDK_CDC2_CDK1_ST	O00443	PIK3C2A	P06493	CDK1	S83	Q84P	84	Missense	proximal	1	no	1.915	4.338	EPSD	COSMIC	3.158	Gain
CMGC_CDK_CDC2_CDK1_ST	O00443	PIK3C2A	P06493	CDK1	T120	V116A	116	Missense	distal	-4	no	3.322	3.416	EPSD	COSMIC	3.158	Up-regulation
CMGC_CDK_CDC2_CDK1_ST	O00443	PIK3C2A	P06493	CDK1	S409	N416H	416	Missense	distal	7	no	3.893	3.894	EPSD	COSMIC	3.158	Up-regulation
CMGC_CDK_CDC2_CDK1_ST	O00443	PIK3C2A	P06493	CDK1	S1553	G1560V	1560	Missense	distal	7	no	3.577	3.573	EPSD	COSMIC	3.158	Down-regulation
CMGC_CDK_CDC2_CDK1_ST	O00443	PIK3C2A	P06493	CDK1	T1555	G1560V	1560	Missense	distal	5	no	3.624	3.592	EPSD	COSMIC	3.158	Down-regulation
CMGC_CDK_CDC2_CDK1_ST	O60701	UGDH	P06493	CDK1	S47	A44V	44	Missense	distal	-3	no	3.347	3.286	EPSD	COSMIC;GDSC;CCLE	3.158	Down-regulation
CMGC_CDK_CDC2_CDK1_ST	O60701	UGDH	P06493	CDK1	S47	E54V	54	Missense	distal	7	no	3.347	3.357	EPSD	COSMIC	3.158	Up-regulation
CMGC_CDK_CDC2_CDK1_ST	O60701	UGDH	P06493	CDK1	S47	N43S	43	Missense	distal	-4	no	3.347	3.420	EPSD	COSMIC	3.158	Up-regulation
CMGC_CDK_CDC2_CDK1_ST	O60701	UGDH	P06493	CDK1	S47	P51L	51	Missense	distal	4	no	3.347	3.225	EPSD	COSMIC	3.158	Down-regulation
CMGC_CDK_CDC2_CDK1_ST	P43307	SSR1	P06493	CDK1	S80	S74F	74	Missense	distal	-6	no	3.256	3.280	EPSD	COSMIC	3.158	Up-regulation
CMGC_CDK_CDC2_CDK1_ST	P43307	SSR1	P06493	CDK1	S80	I87V	87	Missense	distal	7	no	3.256	3.253	EPSD	COSMIC	3.158	Down-regulation
CMGC_CDK_CDC2_CDK1_ST	Q16665	HIF1A	P06493	CDK1	S510	R507K	507	Missense	distal	-3	no	3.732	3.721	EPSD	COSMIC	3.158	Down-regulation
CMGC_CDK_CDC2_CDK1_ST	Q16665	HIF1A	P06493	CDK1	S510	E512V	512	Missense	proximal	2	no	3.732	3.738	EPSD	COSMIC;GDSC	3.158	Up-regulation
CMGC_CDK_CDC2_CDK1_ST	Q16665	HIF1A	P06493	CDK1	S510	P516H	516	Missense	distal	6	no	3.732	3.726	EPSD	COSMIC	3.158	Down-regulation
CMGC_CDK_CDC2_CDK1_ST	Q16665	HIF1A	P06493	CDK1	S510	S517T	517	Missense	distal	7	no	3.732	3.735	EPSD	COSMIC	3.158	Up-regulation
CMGC_CDK_CDC2_CDK1_ST	Q16665	HIF1A	P06493	CDK1	S510	D503N	503	Missense	distal	-7	no	3.732	3.733	EPSD	COSMIC	3.158	Up-regulation
CMGC_CDK_CDC2_CDK1_ST	P20700	LMNB1	P06493	CDK1	S391	V398M	398	Missense	distal	7	no	3.303	3.291	EPSD	COSMIC	3.158	Down-regulation
CMGC_CDK_CDC2_CDK1_ST	P20700	LMNB1	P06493	CDK1	S393	V398M	398	Missense	distal	5	no	3.361	3.280	EPSD;PhosphoSitePlus	COSMIC	3.158	Down-regulation
CMGC_CDK_CDC2_CDK1_ST	P20700	LMNB1	P06493	CDK1	T575	A578S	578	Missense	distal	3	no	3.452	3.399	EPSD	COSMIC	3.158	Down-regulation
CMGC_CDK_CDC2_CDK1_ST	Q01196	RUNX1	P06493	CDK1	S21	K24N	24	Missense	distal	3	no	3.490	3.442	EPSD	COSMIC	3.158	Down-regulation
CMGC_CDK_CDC2_CDK1_ST	Q01196	RUNX1	P06493	CDK1	S21	M25K	25	Missense	distal	4	no	3.490	3.510	EPSD	COSMIC	3.158	Up-regulation
CMGC_CDK_CDC2_CDK1_ST	Q01196	RUNX1	P06493	CDK1	S21	E27Q	27	Missense	distal	6	no	3.490	3.501	EPSD	COSMIC	3.158	Up-regulation
CMGC_CDK_CDC2_CDK1_ST	Q01196	RUNX1	P06493	CDK1	S21	A28E	28	Missense	distal	7	no	3.490	3.515	EPSD	COSMIC	3.158	Up-regulation
CMGC_CDK_CDC2_CDK1_ST	Q01196	RUNX1	P06493	CDK1	S21	P22L	22	Missense	proximal	1	no	3.490	-0.196	EPSD	COSMIC;CCLE	3.158	Loss
CMGC_CDK_CDC2_CDK1_ST	Q01196	RUNX1	P06493	CDK1	S21	P22Q	22	Missense	proximal	1	no	3.490	1.068	EPSD	COSMIC	3.158	Loss
CMGC_CDK_CDC2_CDK1_ST	Q01196	RUNX1	P06493	CDK1	S21	E27K	27	Missense	distal	6	no	3.490	3.493	EPSD	COSMIC	3.158	Up-regulation
CMGC_CDK_CDC2_CDK1_ST	Q01196	RUNX1	P06493	CDK1	S21	T14M	14	Missense	distal	-7	no	3.490	3.402	EPSD	COSMIC	3.158	Down-regulation
CMGC_CDK_CDC2_CDK1_ST	Q01196	RUNX1	P06493	CDK1	S266	S268F	268	Missense	proximal	2	no	3.396	3.418	EPSD	COSMIC	3.158	Up-regulation
CMGC_CDK_CDC2_CDK1_ST	Q01196	RUNX1	P06493	CDK1	S266	P267S	267	Missense	proximal	1	no	3.396	0.212	EPSD	COSMIC	3.158	Loss
CMGC_CDK_CDC2_CDK1_ST	Q01196	RUNX1	P06493	CDK1	S266	T273M	273	Missense	distal	7	no	3.396	3.404	EPSD	COSMIC	3.158	Up-regulation
CMGC_CDK_CDC2_CDK1_ST	Q01196	RUNX1	P06493	CDK1	S266	G262R	262	Missense	distal	-4	no	3.396	3.468	EPSD	COSMIC	3.158	Up-regulation
CMGC_CDK_CDC2_CDK1_ST	Q01196	RUNX1	P06493	CDK1	S266	P271Q	271	Missense	distal	5	no	3.396	3.382	EPSD	COSMIC	3.158	Down-regulation
CMGC_CDK_CDC2_CDK1_ST	Q01196	RUNX1	P06493	CDK1	S266	Y260F	260	Missense	distal	-6	no	3.396	3.403	EPSD	COSMIC	3.158	Up-regulation
CMGC_CDK_CDC2_CDK1_ST	Q01196	RUNX1	P06493	CDK1	S266	P271S	271	Missense	distal	5	no	3.396	3.368	EPSD	COSMIC	3.158	Down-regulation
CMGC_CDK_CDC2_CDK1_ST	Q01196	RUNX1	P06493	CDK1	S266	A265S	265	Missense	proximal	-1	no	3.396	3.450	EPSD	COSMIC	3.158	Up-regulation
CMGC_CDK_CDC2_CDK1_ST	Q01196	RUNX1	P06493	CDK1	S266	L261P	261	Missense	distal	-5	no	3.396	3.275	EPSD	COSMIC	3.158	Down-regulation
CMGC_CDK_CDC2_CDK1_ST	Q01196	RUNX1	P06493	CDK1	S266	A272G	272	Missense	distal	6	no	3.396	3.332	EPSD	COSMIC	3.158	Down-regulation
CMGC_CDK_CDC2_CDK1_ST	Q01196	RUNX1	P06493	CDK1	S435	A440V	440	Missense	distal	5	no	3.236	3.443	EPSD	COSMIC	3.158	Up-regulation
CMGC_CDK_CDC2_CDK1_ST	Q01196	RUNX1	P06493	CDK1	S435	S433N	433	Missense	proximal	-2	no	3.236	3.265	EPSD	COSMIC	3.158	Up-regulation
CMGC_CDK_CDC2_CDK1_ST	Q01196	RUNX1	P06493	CDK1	S435	P436C	436	Missense	proximal	1	no	3.236	0.391	EPSD	COSMIC	3.158	Loss
CMGC_CDK_CDC2_CDK1_ST	Q01196	RUNX1	P06493	CDK1	S435	S442F	442	Missense	distal	7	no	3.236	3.258	EPSD	COSMIC	3.158	Up-regulation
CMGC_CDK_CDC2_CDK1_ST	Q01196	RUNX1	P06493	CDK1	S435	E429K	429	Missense	distal	-6	no	3.236	3.237	EPSD	COSMIC	3.158	Up-regulation
CMGC_CDK_CDC2_CDK1_ST	Q01196	RUNX1	P06493	CDK1	S435	S431G	431	Missense	distal	-4	no	3.236	3.098	EPSD	COSMIC	3.158	Loss
CMGC_CDK_CDC2_CDK1_ST	Q01196	RUNX1	P06493	CDK1	S435	M439L	439	Missense	distal	4	no	3.236	3.149	EPSD	COSMIC;CCLE	3.158	Loss
CMGC_CDK_CDC2_CDK1_ST	Q01196	RUNX1	P06493	CDK1	S435	M439T	439	Missense	distal	4	no	3.236	3.276	EPSD	COSMIC	3.158	Up-regulation
CMGC_CDK_CDC2_CDK1_ST	Q01094	E2F1	P06493	CDK1	S121	H114Y	114	Missense	distal	-7	no	3.476	3.422	EPSD	COSMIC	3.158	Down-regulation
CMGC_CDK_CDC2_CDK1_ST	Q01094	E2F1	P06493	CDK1	S121	R127L	127	Missense	distal	6	no	3.476	3.407	EPSD	COSMIC	3.158	Down-regulation
CMGC_CDK_CDC2_CDK1_ST	Q01094	E2F1	P06493	CDK1	S121	G116V	116	Missense	distal	-5	no	3.476	3.467	EPSD	COSMIC	3.158	Down-regulation
CMGC_CDK_CDC2_CDK1_ST	Q01094	E2F1	P06493	CDK1	S307	P312L	312	Missense	distal	5	no	3.140	3.324	EPSD	COSMIC	3.158	Gain
CMGC_CDK_CDC2_CDK1_ST	Q01094	E2F1	P06493	CDK1	T311	S318F	318	Missense	distal	7	no	3.452	3.475	EPSD	COSMIC	3.158	Up-regulation
CMGC_CDK_CDC2_CDK1_ST	Q01094	E2F1	P06493	CDK1	T311	P312L	312	Missense	proximal	1	no	3.452	-0.234	EPSD	COSMIC	3.158	Loss
CMGC_CDK_CDC2_CDK1_ST	Q01094	E2F1	P06493	CDK1	S337	S341F	341	Missense	distal	4	no	3.293	3.197	EPSD;PhosphoSitePlus	COSMIC	3.158	Down-regulation
CMGC_CDK_CDC2_CDK1_ST	Q01094	E2F1	P06493	CDK1	S337	S336L	336	Missense	proximal	-1	no	3.293	3.495	EPSD;PhosphoSitePlus	COSMIC	3.158	Up-regulation
CMGC_CDK_CDC2_CDK1_ST	Q01094	E2F1	P06493	CDK1	S337	I330T	330	Missense	distal	-7	no	3.293	3.466	EPSD;PhosphoSitePlus	COSMIC	3.158	Up-regulation
CMGC_CDK_CDC2_CDK1_ST	Q01094	E2F1	P06493	CDK1	S337	P335Q	335	Missense	proximal	-2	no	3.293	3.432	EPSD;PhosphoSitePlus	COSMIC;GDSC;CCLE	3.158	Up-regulation
CMGC_CDK_CDC2_CDK1_ST	Q01094	E2F1	P06493	CDK1	S337	P335S	335	Missense	proximal	-2	no	3.293	3.419	EPSD;PhosphoSitePlus	COSMIC	3.158	Up-regulation
CMGC_CDK_CDC2_CDK1_ST	Q01094	E2F1	P06493	CDK1	S337	P334L	334	Missense	distal	-3	no	3.293	3.261	EPSD;PhosphoSitePlus	COSMIC	3.158	Down-regulation
CMGC_CDK_CDC2_CDK1_ST	Q01094	E2F1	P06493	CDK1	S375	S382L	382	Missense	distal	7	no	3.327	3.357	EPSD	COSMIC	3.158	Up-regulation
CMGC_CDK_CDC2_CDK1_ST	Q01094	E2F1	P06493	CDK1	S403	P404S	404	Missense	proximal	1	no	3.534	0.349	EPSD	COSMIC	3.158	Loss
CMGC_CDK_CDC2_CDK1_ST	Q8IWB6	TEX14	P06493	CDK1	T554	E549K	549	Missense	distal	-5	no	3.347	3.377	EPSD	COSMIC	3.158	Up-regulation
CMGC_CDK_CDC2_CDK1_ST	Q8IWB6	TEX14	P06493	CDK1	T554	T554K	554	Missense	central	0	yes	3.347	0.000	EPSD	COSMIC	3.158	Loss
CMGC_CDK_CDC2_CDK1_ST	Q8IWB6	TEX14	P06493	CDK1	T1277	R1281T	1281	Missense	distal	4	no	3.674	3.664	EPSD	COSMIC	3.158	Down-regulation
CMGC_CDK_CDC2_CDK1_ST	Q8IWB6	TEX14	P06493	CDK1	T1277	S1275A	1275	Missense	proximal	-2	no	3.674	3.554	EPSD	COSMIC	3.158	Down-regulation
CMGC_CDK_CDC2_CDK1_ST	Q8IWB6	TEX14	P06493	CDK1	T1277	S1275F	1275	Missense	proximal	-2	no	3.674	3.741	EPSD	COSMIC	3.158	Up-regulation
CMGC_CDK_CDC2_CDK1_ST	Q8IWB6	TEX14	P06493	CDK1	T1277	T1273A	1273	Missense	distal	-4	no	3.674	3.638	EPSD	COSMIC	3.158	Down-regulation
CMGC_CDK_CDC2_CDK1_ST	Q8IWB6	TEX14	P06493	CDK1	T1277	L1282P	1282	Missense	distal	5	no	3.674	3.489	EPSD	COSMIC	3.158	Down-regulation
CMGC_CDK_CDC2_CDK1_ST	P98170	XIAP	P06493	CDK1	S40	G39D	39	Missense	proximal	-1	no	3.582	3.447	PhosphoSitePlus	COSMIC	3.158	Down-regulation
CMGC_CDK_CDC2_CDK1_ST	Q04637	EIF4G1	P06493	CDK1	S134	T136M	136	Missense	proximal	2	no	3.596	3.605	EPSD	COSMIC	3.158	Up-regulation
CMGC_CDK_CDC2_CDK1_ST	Q04637	EIF4G1	P06493	CDK1	S134	G139W	139	Missense	distal	5	no	3.596	3.517	EPSD	COSMIC	3.158	Down-regulation
CMGC_CDK_CDC2_CDK1_ST	Q04637	EIF4G1	P06493	CDK1	T205	G199D	199	Missense	distal	-6	no	3.267	3.254	EPSD	COSMIC	3.158	Down-regulation
CMGC_CDK_CDC2_CDK1_ST	Q04637	EIF4G1	P06493	CDK1	T205	P208L	208	Missense	distal	3	no	3.267	3.134	EPSD	COSMIC	3.158	Loss
CMGC_CDK_CDC2_CDK1_ST	Q04637	EIF4G1	P06493	CDK1	T205	S204T	204	Missense	proximal	-1	no	3.267	3.240	EPSD	COSMIC	3.158	Down-regulation
CMGC_CDK_CDC2_CDK1_ST	Q04637	EIF4G1	P06493	CDK1	T205	R201C	201	Missense	distal	-4	no	3.267	3.198	EPSD	COSMIC	3.158	Down-regulation
CMGC_CDK_CDC2_CDK1_ST	Q04637	EIF4G1	P06493	CDK1	T205	R201H	201	Missense	distal	-4	no	3.267	3.263	EPSD	COSMIC	3.158	Down-regulation
CMGC_CDK_CDC2_CDK1_ST	Q04637	EIF4G1	P06493	CDK1	T205	T211M	211	Missense	distal	6	no	3.267	3.243	EPSD	COSMIC	3.158	Down-regulation
CMGC_CDK_CDC2_CDK1_ST	Q04637	EIF4G1	P06493	CDK1	S263	P270S	270	Missense	distal	7	no	3.571	3.569	EPSD	COSMIC	3.158	Down-regulation
CMGC_CDK_CDC2_CDK1_ST	Q04637	EIF4G1	P06493	CDK1	S263	E256K	256	Missense	distal	-7	no	3.571	3.526	EPSD	COSMIC	3.158	Down-regulation
CMGC_CDK_CDC2_CDK1_ST	Q04637	EIF4G1	P06493	CDK1	S263	T265K	265	Missense	proximal	2	no	3.571	3.576	EPSD	COSMIC	3.158	Up-regulation
CMGC_CDK_CDC2_CDK1_ST	Q04637	EIF4G1	P06493	CDK1	S263	S260L	260	Missense	distal	-3	no	3.571	3.540	EPSD	COSMIC	3.158	Down-regulation
CMGC_CDK_CDC2_CDK1_ST	Q04637	EIF4G1	P06493	CDK1	S263	S269Y	269	Missense	distal	6	no	3.571	3.533	EPSD	COSMIC	3.158	Down-regulation
CMGC_CDK_CDC2_CDK1_ST	Q04637	EIF4G1	P06493	CDK1	S263	P264S	264	Missense	proximal	1	no	3.571	0.387	EPSD	COSMIC	3.158	Loss
CMGC_CDK_CDC2_CDK1_ST	Q04637	EIF4G1	P06493	CDK1	S263	P266S	266	Missense	distal	3	no	3.571	3.621	EPSD	COSMIC	3.158	Up-regulation
CMGC_CDK_CDC2_CDK1_ST	Q04637	EIF4G1	P06493	CDK1	S263	S269F	269	Missense	distal	6	no	3.571	3.520	EPSD	COSMIC	3.158	Down-regulation
CMGC_CDK_CDC2_CDK1_ST	Q04637	EIF4G1	P06493	CDK1	S267	T265K	265	Missense	proximal	-2	no	3.094	3.200	EPSD	COSMIC	3.158	Gain
CMGC_CDK_CDC2_CDK1_ST	Q04637	EIF4G1	P06493	CDK1	T301	E306D	306	Missense	distal	5	no	3.485	3.493	EPSD	COSMIC	3.158	Up-regulation
CMGC_CDK_CDC2_CDK1_ST	Q04637	EIF4G1	P06493	CDK1	T301	E298D	298	Missense	distal	-3	no	3.485	3.494	EPSD	COSMIC	3.158	Up-regulation
CMGC_CDK_CDC2_CDK1_ST	Q04637	EIF4G1	P06493	CDK1	T301	E299D	299	Missense	proximal	-2	no	3.485	3.465	EPSD	COSMIC;GDSC;CCLE	3.158	Down-regulation
CMGC_CDK_CDC2_CDK1_ST	Q04637	EIF4G1	P06493	CDK1	T301	S300L	300	Missense	proximal	-1	no	3.485	3.687	EPSD	COSMIC	3.158	Up-regulation
CMGC_CDK_CDC2_CDK1_ST	Q04637	EIF4G1	P06493	CDK1	S314	P315S	315	Missense	proximal	1	no	3.471	0.287	EPSD	COSMIC	3.158	Loss
CMGC_CDK_CDC2_CDK1_ST	Q04637	EIF4G1	P06493	CDK1	S314	R312H	312	Missense	proximal	-2	no	3.471	3.425	EPSD	COSMIC	3.158	Down-regulation
CMGC_CDK_CDC2_CDK1_ST	Q04637	EIF4G1	P06493	CDK1	T647	K643T	643	Missense	distal	-4	no	3.072	3.193	EPSD	COSMIC	3.158	Gain
CMGC_CDK_CDC2_CDK1_ST	Q04637	EIF4G1	P06493	CDK1	S895	L896P	896	Missense	proximal	1	no	-0.476	3.210	EPSD	COSMIC	3.158	Gain
CMGC_CDK_CDC2_CDK1_ST	Q04637	EIF4G1	P06493	CDK1	S1231	A1236V	1236	Missense	distal	5	no	3.069	3.276	PhosphoSitePlus	COSMIC	3.158	Gain
CMGC_CDK_CDC2_CDK1_ST	Q04637	EIF4G1	P06493	CDK1	T1495	I1491T	1491	Missense	distal	-4	no	3.101	3.253	EPSD	COSMIC	3.158	Gain
CMGC_CDK_CDC2_CDK1_ST	Q04637	EIF4G1	P06493	CDK1	T1495	I1491N	1491	Missense	distal	-4	no	3.101	3.172	EPSD	COSMIC	3.158	Gain
CMGC_CDK_CDC2_CDK1_ST	Q04637	EIF4G1	P06493	CDK1	T1495	D1500G	1500	Missense	distal	5	no	3.101	3.196	EPSD	COSMIC	3.158	Gain
CMGC_CDK_CDC2_CDK1_ST	P48200	IREB2	P06493	CDK1	S157	S157F	157	Missense	central	0	yes	3.545	0.000	PhosphoSitePlus	COSMIC	3.158	Loss
CMGC_CDK_CDC2_CDK1_ST	P48200	IREB2	P06493	CDK1	T777	L771F	771	Missense	distal	-6	no	3.293	3.288	EPSD	COSMIC	3.158	Down-regulation
CMGC_CDK_CDC2_CDK1_ST	P48200	IREB2	P06493	CDK1	T777	T777I	777	Missense	central	0	yes	3.293	0.000	EPSD	COSMIC	3.158	Loss
CMGC_CDK_CDC2_CDK1_ST	Q15788	NCOA1	P06493	CDK1	S999	Y995H	995	Missense	distal	-4	no	3.621	3.650	EPSD	COSMIC	3.158	Up-regulation
CMGC_CDK_CDC2_CDK1_ST	Q15788	NCOA1	P06493	CDK1	S999	P994S	994	Missense	distal	-5	no	3.621	3.599	EPSD	COSMIC	3.158	Down-regulation
CMGC_CDK_CDC2_CDK1_ST	Q15788	NCOA1	P06493	CDK1	S1006	R1013S	1013	Missense	distal	7	no	3.320	3.312	EPSD	COSMIC	3.158	Down-regulation
CMGC_CDK_CDC2_CDK1_ST	Q15788	NCOA1	P06493	CDK1	S1006	S999T	999	Missense	distal	-7	no	3.320	3.341	EPSD	COSMIC	3.158	Up-regulation
CMGC_CDK_CDC2_CDK1_ST	Q08050	FOXM1	P06493	CDK1	T510	S505L	505	Missense	distal	-5	no	3.316	3.460	EPSD	COSMIC	3.158	Up-regulation
CMGC_CDK_CDC2_CDK1_ST	Q08050	FOXM1	P06493	CDK1	T510	T510N	510	Missense	central	0	yes	3.316	0.000	EPSD	COSMIC;CCLE	3.158	Loss
CMGC_CDK_CDC2_CDK1_ST	Q08050	FOXM1	P06493	CDK1	T600	T605M	605	Missense	distal	5	no	3.397	3.460	EPSD;PhosphoSitePlus	COSMIC	3.158	Up-regulation
CMGC_CDK_CDC2_CDK1_ST	Q08050	FOXM1	P06493	CDK1	T611	S615Y	615	Missense	distal	4	no	3.175	3.106	PhosphoSitePlus;EPSD	COSMIC	3.158	Loss
CMGC_CDK_CDC2_CDK1_ST	Q08050	FOXM1	P06493	CDK1	T611	S610T	610	Missense	proximal	-1	no	3.175	3.148	PhosphoSitePlus;EPSD	COSMIC	3.158	Loss
CMGC_CDK_CDC2_CDK1_ST	Q08050	FOXM1	P06493	CDK1	T611	T605M	605	Missense	distal	-6	no	3.175	3.186	PhosphoSitePlus;EPSD	COSMIC	3.158	Up-regulation
CMGC_CDK_CDC2_CDK1_ST	Q08050	FOXM1	P06493	CDK1	S672	P673S	673	Missense	proximal	1	no	3.341	0.157	EPSD	COSMIC	3.158	Loss
CMGC_CDK_CDC2_CDK1_ST	Q08050	FOXM1	P06493	CDK1	S672	R675K	675	Missense	distal	3	no	3.341	3.324	EPSD	COSMIC	3.158	Down-regulation
CMGC_CDK_CDC2_CDK1_ST	Q08050	FOXM1	P06493	CDK1	S672	S666N	666	Missense	distal	-6	no	3.341	3.350	EPSD	COSMIC	3.158	Up-regulation
CMGC_CDK_CDC2_CDK1_ST	Q08050	FOXM1	P06493	CDK1	S672	P669L	669	Missense	distal	-3	no	3.341	3.310	EPSD	COSMIC	3.158	Down-regulation
CMGC_CDK_CDC2_CDK1_ST	Q08050	FOXM1	P06493	CDK1	S672	L670P	670	Missense	proximal	-2	no	3.341	3.168	EPSD	COSMIC	3.158	Down-regulation
CMGC_CDK_CDC2_CDK1_ST	O94762	RECQL5	P06493	CDK1	T31	F26C	26	Missense	distal	-5	no	3.369	3.350	EPSD	COSMIC	3.158	Down-regulation
CMGC_CDK_CDC2_CDK1_ST	O94762	RECQL5	P06493	CDK1	T31	F29Y	29	Missense	proximal	-2	no	3.369	3.352	EPSD	COSMIC	3.158	Down-regulation
CMGC_CDK_CDC2_CDK1_ST	P18754	RCC1	P06493	CDK1	T274	P275S	275	Missense	proximal	1	no	3.303	0.118	PhosphoSitePlus;EPSD	COSMIC	3.158	Loss
CMGC_CDK_CDC2_CDK1_ST	P18754	RCC1	P06493	CDK1	T274	P275L	275	Missense	proximal	1	no	3.303	-0.384	PhosphoSitePlus;EPSD	COSMIC	3.158	Loss
CMGC_CDK_CDC2_CDK1_ST	Q14807	KIF22	P06493	CDK1	S140	S140N	140	Missense	central	0	yes	4.466	0.000	EPSD	COSMIC	3.158	Loss
CMGC_CDK_CDC2_CDK1_ST	Q14807	KIF22	P06493	CDK1	S140	S140R	140	Missense	central	0	yes	4.466	0.000	EPSD	COSMIC	3.158	Loss
CMGC_CDK_CDC2_CDK1_ST	Q14807	KIF22	P06493	CDK1	T463	T463I	463	Missense	central	0	yes	3.490	0.000	EPSD;PhosphoSitePlus	COSMIC	3.158	Loss
CMGC_CDK_CDC2_CDK1_ST	Q9Y6Q9	NCOA3	P06493	CDK1	T24	R18C	18	Missense	distal	-6	no	3.742	3.751	EPSD	COSMIC	3.158	Up-regulation
CMGC_CDK_CDC2_CDK1_ST	Q9Y6Q9	NCOA3	P06493	CDK1	T24	K19R	19	Missense	distal	-5	no	3.742	3.715	EPSD	COSMIC	3.158	Down-regulation
CMGC_CDK_CDC2_CDK1_ST	Q9Y6Q9	NCOA3	P06493	CDK1	T24	L20W	20	Missense	distal	-4	no	3.742	3.829	EPSD	COSMIC	3.158	Up-regulation
CMGC_CDK_CDC2_CDK1_ST	Q9Y6Q9	NCOA3	P06493	CDK1	S505	P499L	499	Missense	distal	-6	no	3.211	3.238	EPSD	COSMIC;GDSC;CCLE	3.158	Up-regulation
CMGC_CDK_CDC2_CDK1_ST	Q9Y6Q9	NCOA3	P06493	CDK1	S505	V503M	503	Missense	proximal	-2	no	3.211	3.183	EPSD	COSMIC	3.158	Down-regulation
CMGC_CDK_CDC2_CDK1_ST	Q9Y6Q9	NCOA3	P06493	CDK1	S505	H504Y	504	Missense	proximal	-1	no	3.211	3.274	EPSD	COSMIC	3.158	Up-regulation
CMGC_CDK_CDC2_CDK1_ST	Q9Y6Q9	NCOA3	P06493	CDK1	S505	A508T	508	Missense	distal	3	no	3.211	3.124	EPSD	COSMIC;GDSC;CCLE	3.158	Loss
CMGC_CDK_CDC2_CDK1_ST	Q9Y6Q9	NCOA3	P06493	CDK1	S543	K547T	547	Missense	distal	4	no	3.666	3.687	EPSD	COSMIC	3.158	Up-regulation
CMGC_CDK_CDC2_CDK1_ST	Q9Y6Q9	NCOA3	P06493	CDK1	S543	S543P	543	Missense	central	0	yes	3.666	0.000	EPSD	COSMIC	3.158	Loss
CMGC_CDK_CDC2_CDK1_ST	Q9Y6Q9	NCOA3	P06493	CDK1	S543	D549N	549	Missense	distal	6	no	3.666	3.674	EPSD	COSMIC	3.158	Up-regulation
CMGC_CDK_CDC2_CDK1_ST	Q9Y6Q9	NCOA3	P06493	CDK1	S551	K547T	547	Missense	distal	-4	no	3.569	3.690	EPSD	COSMIC	3.158	Up-regulation
CMGC_CDK_CDC2_CDK1_ST	Q9Y6Q9	NCOA3	P06493	CDK1	S551	D549N	549	Missense	proximal	-2	no	3.569	3.580	EPSD	COSMIC	3.158	Up-regulation
CMGC_CDK_CDC2_CDK1_ST	P02545	LMNA	P06493	CDK1	T19	G13A	13	Missense	distal	-6	no	3.189	3.164	PhosphoSitePlus;EPSD	COSMIC	3.158	Down-regulation
CMGC_CDK_CDC2_CDK1_ST	P02545	LMNA	P06493	CDK1	S390	E383K	383	Missense	distal	-7	no	3.258	3.213	EPSD;PhosphoSitePlus	COSMIC;GDSC;CCLE	3.158	Down-regulation
CMGC_CDK_CDC2_CDK1_ST	P02545	LMNA	P06493	CDK1	S390	R388L	388	Missense	proximal	-2	no	3.258	3.239	EPSD;PhosphoSitePlus	COSMIC	3.158	Down-regulation
CMGC_CDK_CDC2_CDK1_ST	P02545	LMNA	P06493	CDK1	S390	L389R	389	Missense	proximal	-1	no	3.258	3.119	EPSD;PhosphoSitePlus	COSMIC	3.158	Loss
CMGC_CDK_CDC2_CDK1_ST	P02545	LMNA	P06493	CDK1	S657	I663M	663	Missense	distal	6	no	3.356	3.383	EPSD	COSMIC	3.158	Up-regulation
CMGC_CDK_CDC2_CDK1_ST	P02545	LMNA	P06493	CDK1	S657	Q659L	659	Missense	proximal	2	no	3.356	3.375	EPSD	COSMIC	3.158	Up-regulation
CMGC_CDK_CDC2_CDK1_ST	P02545	LMNA	P06493	CDK1	S657	R654Q	654	Missense	distal	-3	no	3.356	3.378	EPSD	COSMIC	3.158	Up-regulation
CMGC_CDK_CDC2_CDK1_ST	Q9UNH5	CDC14A	P06493	CDK1	S453	S455L	455	Missense	proximal	2	no	3.145	3.167	PhosphoSitePlus;EPSD	COSMIC	3.158	Gain
CMGC_CDK_CDC2_CDK1_ST	P55273	CDKN2D	P06493	CDK1	S66	T72I	72	Missense	distal	6	no	3.975	3.923	EPSD	COSMIC	3.158	Down-regulation
CMGC_CDK_CDC2_CDK1_ST	P55273	CDKN2D	P06493	CDK1	T141	A146V	146	Missense	distal	5	no	3.011	3.218	EPSD	COSMIC	3.158	Gain
CMGC_CDK_CDC2_CDK1_ST	P0C1Z6	TFPT	P06493	CDK1	S167	P161S	161	Missense	distal	-6	no	3.460	3.458	EPSD	COSMIC	3.158	Down-regulation
CMGC_CDK_CDC2_CDK1_ST	P0C1Z6	TFPT	P06493	CDK1	S167	R171S	171	Missense	distal	4	no	3.460	3.442	EPSD	COSMIC	3.158	Down-regulation
CMGC_CDK_CDC2_CDK1_ST	O43683	BUB1	P06493	CDK1	T440	T441P	441	Missense	proximal	1	no	0.859	3.293	EPSD	COSMIC;GDSC;CCLE	3.158	Gain
CMGC_CDK_CDC2_CDK1_ST	O43683	BUB1	P06493	CDK1	T452	P458Q	458	Missense	distal	6	no	3.285	3.281	EPSD	COSMIC	3.158	Down-regulation
CMGC_CDK_CDC2_CDK1_ST	O43683	BUB1	P06493	CDK1	S459	P460L	460	Missense	proximal	1	no	3.196	-0.490	EPSD	COSMIC	3.158	Loss
CMGC_CDK_CDC2_CDK1_ST	O43683	BUB1	P06493	CDK1	S459	T461A	461	Missense	proximal	2	no	3.196	3.190	EPSD	COSMIC	3.158	Down-regulation
CMGC_CDK_CDC2_CDK1_ST	O43683	BUB1	P06493	CDK1	T609	V616A	616	Missense	distal	7	no	3.377	3.343	PhosphoSitePlus;EPSD	COSMIC	3.158	Down-regulation
CMGC_CDK_CDC2_CDK1_ST	O43683	BUB1	P06493	CDK1	T609	A607V	607	Missense	proximal	-2	no	3.377	3.542	PhosphoSitePlus;EPSD	COSMIC	3.158	Up-regulation
CMGC_CDK_CDC2_CDK1_ST	O43683	BUB1	P06493	CDK1	S655	P662L	662	Missense	distal	7	no	3.213	3.241	EPSD	COSMIC;GDSC	3.158	Up-regulation
CMGC_CDK_CDC2_CDK1_ST	Q14674	ESPL1	P06493	CDK1	T1210	P1216S	1216	Missense	distal	6	no	3.327	3.334	EPSD	COSMIC;GDSC;CCLE	3.158	Up-regulation
CMGC_CDK_CDC2_CDK1_ST	Q14674	ESPL1	P06493	CDK1	T1210	S1213T	1213	Missense	distal	3	no	3.327	3.292	EPSD	COSMIC	3.158	Down-regulation
CMGC_CDK_CDC2_CDK1_ST	Q14674	ESPL1	P06493	CDK1	T1210	L1214F	1214	Missense	distal	4	no	3.327	3.349	EPSD	COSMIC	3.158	Up-regulation
CMGC_CDK_CDC2_CDK1_ST	Q14674	ESPL1	P06493	CDK1	T1210	S1213F	1213	Missense	distal	3	no	3.327	3.196	EPSD	COSMIC	3.158	Down-regulation
CMGC_CDK_CDC2_CDK1_ST	Q14674	ESPL1	P06493	CDK1	T1346	R1352W	1352	Missense	distal	6	no	3.511	3.473	EPSD	COSMIC	3.158	Down-regulation
CMGC_CDK_CDC2_CDK1_ST	Q14674	ESPL1	P06493	CDK1	T1346	D1351E	1351	Missense	distal	5	no	3.511	3.503	EPSD	COSMIC	3.158	Down-regulation
CMGC_CDK_CDC2_CDK1_ST	Q14674	ESPL1	P06493	CDK1	T1346	P1344L	1344	Missense	proximal	-2	no	3.511	3.684	EPSD	COSMIC	3.158	Up-regulation
CMGC_CDK_CDC2_CDK1_ST	P54132	BLM	P06493	CDK1	T125	V118I	118	Missense	distal	-7	no	3.172	3.144	EPSD	COSMIC	3.158	Loss
CMGC_CDK_CDC2_CDK1_ST	P54132	BLM	P06493	CDK1	T125	P126S	126	Missense	proximal	1	no	3.172	-0.013	EPSD	COSMIC	3.158	Loss
CMGC_CDK_CDC2_CDK1_ST	P54132	BLM	P06493	CDK1	T125	S131P	131	Missense	distal	6	no	3.172	3.165	EPSD	COSMIC;CCLE	3.158	Down-regulation
CMGC_CDK_CDC2_CDK1_ST	P54132	BLM	P06493	CDK1	S579	S580P	580	Missense	proximal	1	no	0.258	3.443	EPSD	COSMIC	3.158	Gain
CMGC_CDK_CDC2_CDK1_ST	P54132	BLM	P06493	CDK1	S706	S706F	706	Missense	central	0	yes	3.363	0.000	EPSD	COSMIC	3.158	Loss
CMGC_CDK_CDC2_CDK1_ST	P54132	BLM	P06493	CDK1	S714	V721I	721	Missense	distal	7	no	3.348	3.350	PhosphoSitePlus;EPSD	COSMIC;GDSC;CCLE	3.158	Up-regulation
CMGC_CDK_CDC2_CDK1_ST	P54132	BLM	P06493	CDK1	S1296	S1302F	1302	Missense	distal	6	no	3.287	3.235	EPSD	COSMIC	3.158	Down-regulation
CMGC_CDK_CDC2_CDK1_ST	P54132	BLM	P06493	CDK1	S1296	S1290L	1290	Missense	distal	-6	no	3.287	3.315	EPSD	COSMIC	3.158	Up-regulation
CMGC_CDK_CDC2_CDK1_ST	P54274	TERF1	P06493	CDK1	T149	P150S	150	Missense	proximal	1	no	3.214	0.030	EPSD	COSMIC;GDSC;CCLE	3.158	Loss
CMGC_CDK_CDC2_CDK1_ST	P68400	CSNK2A1	P06493	CDK1	T360	T360I	360	Missense	central	0	yes	3.753	0.000	EPSD;PhosphoSitePlus	COSMIC	3.158	Loss
CMGC_CDK_CDC2_CDK1_ST	P68400	CSNK2A1	P06493	CDK1	T360	L364R	364	Missense	distal	4	no	3.753	3.890	EPSD;PhosphoSitePlus	COSMIC	3.158	Up-regulation
CMGC_CDK_CDC2_CDK1_ST	P68400	CSNK2A1	P06493	CDK1	T360	P361H	361	Missense	proximal	1	no	3.753	1.069	EPSD;PhosphoSitePlus	COSMIC	3.158	Loss
CMGC_CDK_CDC2_CDK1_ST	P68400	CSNK2A1	P06493	CDK1	S362	T360I	360	Missense	proximal	-2	no	3.331	3.464	EPSD;PhosphoSitePlus	COSMIC	3.158	Up-regulation
CMGC_CDK_CDC2_CDK1_ST	P68400	CSNK2A1	P06493	CDK1	S362	L364R	364	Missense	proximal	2	no	3.331	3.316	EPSD;PhosphoSitePlus	COSMIC	3.158	Down-regulation
CMGC_CDK_CDC2_CDK1_ST	P68400	CSNK2A1	P06493	CDK1	S362	A368D	368	Missense	distal	6	no	3.331	3.297	EPSD;PhosphoSitePlus	COSMIC	3.158	Down-regulation
CMGC_CDK_CDC2_CDK1_ST	P68400	CSNK2A1	P06493	CDK1	S362	P361H	361	Missense	proximal	-1	no	3.331	3.366	EPSD;PhosphoSitePlus	COSMIC	3.158	Up-regulation
CMGC_CDK_CDC2_CDK1_ST	P30305	CDC25B	P06493	CDK1	S249	F256L	256	Missense	distal	7	no	3.152	3.160	EPSD	COSMIC;GDSC;CCLE	3.158	Gain
CMGC_CDK_CDC2_CDK1_ST	P30305	CDC25B	P06493	CDK1	T355	R352Q	352	Missense	distal	-3	no	3.512	3.535	EPSD	COSMIC	3.158	Up-regulation
CMGC_CDK_CDC2_CDK1_ST	P30305	CDC25B	P06493	CDK1	T355	R350T	350	Missense	distal	-5	no	3.512	3.453	EPSD	COSMIC	3.158	Down-regulation
CMGC_CDK_CDC2_CDK1_ST	P30305	CDC25B	P06493	CDK1	S416	A422T	422	Missense	distal	6	no	3.703	3.695	EPSD	COSMIC	3.158	Down-regulation
CMGC_CDK_CDC2_CDK1_ST	P30305	CDC25B	P06493	CDK1	S416	A422V	422	Missense	distal	6	no	3.703	3.655	EPSD	COSMIC	3.158	Down-regulation
CMGC_CDK_CDC2_CDK1_ST	P30305	CDC25B	P06493	CDK1	S416	Q410K	410	Missense	distal	-6	no	3.703	3.708	EPSD	COSMIC	3.158	Up-regulation
CMGC_CDK_CDC2_CDK1_ST	P30305	CDC25B	P06493	CDK1	S416	P417Q	417	Missense	proximal	1	no	3.703	1.280	EPSD	COSMIC	3.158	Loss
CMGC_CDK_CDC2_CDK1_ST	P30305	CDC25B	P06493	CDK1	S416	L423F	423	Missense	distal	7	no	3.703	3.695	EPSD	COSMIC	3.158	Down-regulation
CMGC_CDK_CDC2_CDK1_ST	P30305	CDC25B	P06493	CDK1	S470	E464G	464	Missense	distal	-6	no	3.246	3.260	EPSD	COSMIC	3.158	Up-regulation
CMGC_CDK_CDC2_CDK1_ST	P30305	CDC25B	P06493	CDK1	S470	E464K	464	Missense	distal	-6	no	3.246	3.248	EPSD	COSMIC	3.158	Up-regulation
CMGC_CDK_CDC2_CDK1_ST	P30305	CDC25B	P06493	CDK1	S470	L477P	477	Missense	distal	7	no	3.246	3.218	EPSD	COSMIC	3.158	Down-regulation
CMGC_CDK_CDC2_CDK1_ST	P30305	CDC25B	P06493	CDK1	S470	A473V	473	Missense	distal	3	no	3.246	3.093	EPSD	COSMIC	3.158	Loss
CMGC_CDK_CDC2_CDK1_ST	P30305	CDC25B	P06493	CDK1	S470	A463T	463	Missense	distal	-7	no	3.246	3.240	EPSD	COSMIC	3.158	Down-regulation
CMGC_CDK_CDC2_CDK1_ST	P30305	CDC25B	P06493	CDK1	S470	K469R	469	Missense	proximal	-1	no	3.246	3.176	EPSD	COSMIC	3.158	Down-regulation
CMGC_CDK_CDC2_CDK1_ST	O00571	DDX3X	P06493	CDK1	T204	R202L	202	Missense	proximal	-2	no	3.248	3.228	PhosphoSitePlus;EPSD	COSMIC	3.158	Down-regulation
CMGC_CDK_CDC2_CDK1_ST	O00571	DDX3X	P06493	CDK1	T204	T198P	198	Missense	distal	-6	no	3.248	3.251	PhosphoSitePlus;EPSD	COSMIC	3.158	Up-regulation
CMGC_CDK_CDC2_CDK1_ST	O00571	DDX3X	P06493	CDK1	T204	A210G	210	Missense	distal	6	no	3.248	3.184	PhosphoSitePlus;EPSD	COSMIC	3.158	Down-regulation
CMGC_CDK_CDC2_CDK1_ST	O00571	DDX3X	P06493	CDK1	T323	G316V	316	Missense	distal	-7	no	3.494	3.528	EPSD;PhosphoSitePlus	COSMIC	3.158	Up-regulation
CMGC_CDK_CDC2_CDK1_ST	O00571	DDX3X	P06493	CDK1	T323	V321L	321	Missense	proximal	-2	no	3.494	3.496	EPSD;PhosphoSitePlus	COSMIC	3.158	Up-regulation
CMGC_CDK_CDC2_CDK1_ST	O00571	DDX3X	P06493	CDK1	T323	G316E	316	Missense	distal	-7	no	3.494	3.585	EPSD;PhosphoSitePlus	COSMIC	3.158	Up-regulation
CMGC_CDK_CDC2_CDK1_ST	O00571	DDX3X	P06493	CDK1	T323	G325E	325	Missense	proximal	2	no	3.494	3.481	EPSD;PhosphoSitePlus	COSMIC	3.158	Down-regulation
CMGC_CDK_CDC2_CDK1_ST	O00571	DDX3X	P06493	CDK1	T323	L319V	319	Missense	distal	-4	no	3.494	3.567	EPSD;PhosphoSitePlus	COSMIC	3.158	Up-regulation
CMGC_CDK_CDC2_CDK1_ST	O00571	DDX3X	P06493	CDK1	T323	L320F	320	Missense	distal	-3	no	3.494	3.498	EPSD;PhosphoSitePlus	COSMIC	3.158	Up-regulation
CMGC_CDK_CDC2_CDK1_ST	O00571	DDX3X	P06493	CDK1	S492	G490V	490	Missense	proximal	-2	no	3.318	3.274	EPSD	COSMIC	3.158	Down-regulation
CMGC_CDK_CDC2_CDK1_ST	O00571	DDX3X	P06493	CDK1	S492	R488H	488	Missense	distal	-4	no	3.318	3.314	EPSD	COSMIC	3.158	Down-regulation
CMGC_CDK_CDC2_CDK1_ST	O00571	DDX3X	P06493	CDK1	S492	G490E	490	Missense	proximal	-2	no	3.318	3.267	EPSD	COSMIC	3.158	Down-regulation
CMGC_CDK_CDC2_CDK1_ST	O00571	DDX3X	P06493	CDK1	S492	T498A	498	Missense	distal	6	no	3.318	3.326	EPSD	COSMIC	3.158	Up-regulation
CMGC_CDK_CDC2_CDK1_ST	O00571	DDX3X	P06493	CDK1	S492	F487I	487	Missense	distal	-5	no	3.318	3.338	EPSD	COSMIC	3.158	Up-regulation
CMGC_CDK_CDC2_CDK1_ST	O00571	DDX3X	P06493	CDK1	S492	S492L	492	Missense	central	0	yes	3.318	0.000	EPSD	COSMIC	3.158	Loss
CMGC_CDK_CDC2_CDK1_ST	Q9UGP4	LIMD1	P06493	CDK1	S197	S197F	197	Missense	central	0	yes	3.435	0.000	EPSD	COSMIC	3.158	Loss
CMGC_CDK_CDC2_CDK1_ST	Q9UGP4	LIMD1	P06493	CDK1	S197	W190R	190	Missense	distal	-7	no	3.435	3.505	EPSD	COSMIC	3.158	Up-regulation
CMGC_CDK_CDC2_CDK1_ST	Q9UGP4	LIMD1	P06493	CDK1	S197	S199R	199	Missense	proximal	2	no	3.435	3.442	EPSD	COSMIC	3.158	Up-regulation
CMGC_CDK_CDC2_CDK1_ST	Q9UGP4	LIMD1	P06493	CDK1	T294	V287L	287	Missense	distal	-7	no	3.302	3.226	EPSD	COSMIC	3.158	Down-regulation
CMGC_CDK_CDC2_CDK1_ST	Q9UGP4	LIMD1	P06493	CDK1	S384	G378D	378	Missense	distal	-6	no	3.807	3.794	EPSD	COSMIC;GDSC;CCLE	3.158	Down-regulation
CMGC_CDK_CDC2_CDK1_ST	Q9UGP4	LIMD1	P06493	CDK1	S424	S424F	424	Missense	central	0	yes	3.218	0.000	EPSD;PhosphoSitePlus	COSMIC	3.158	Loss
CMGC_CDK_CDC2_CDK1_ST	P26368	U2AF2	P06493	CDK1	T135	P136S	136	Missense	proximal	1	no	3.547	0.362	EPSD	COSMIC	3.158	Loss
CMGC_CDK_CDC2_CDK1_ST	P10275	AR	P06493	CDK1	T282	R280H	280	Missense	proximal	-2	no	3.389	3.343	EPSD	COSMIC	3.158	Down-regulation
CMGC_CDK_CDC2_CDK1_ST	P10275	AR	P06493	CDK1	T282	E289G	289	Missense	distal	7	no	3.389	3.402	EPSD	COSMIC	3.158	Up-regulation
CMGC_CDK_CDC2_CDK1_ST	P10275	AR	P06493	CDK1	T282	P276S	276	Missense	distal	-6	no	3.389	3.387	EPSD	COSMIC	3.158	Down-regulation
CMGC_CDK_CDC2_CDK1_ST	P10275	AR	P06493	CDK1	T282	P283S	283	Missense	proximal	1	no	3.389	0.204	EPSD	COSMIC	3.158	Loss
CMGC_CDK_CDC2_CDK1_ST	P10275	AR	P06493	CDK1	T282	A278T	278	Missense	distal	-4	no	3.389	3.424	EPSD	COSMIC	3.158	Up-regulation
CMGC_CDK_CDC2_CDK1_ST	P10275	AR	P06493	CDK1	T282	A285D	285	Missense	distal	3	no	3.389	3.267	EPSD	COSMIC	3.158	Down-regulation
CMGC_CDK_CDC2_CDK1_ST	P10275	AR	P06493	CDK1	T282	A278V	278	Missense	distal	-4	no	3.389	3.294	EPSD	COSMIC	3.158	Down-regulation
CMGC_CDK_CDC2_CDK1_ST	P10275	AR	P06493	CDK1	T282	A285V	285	Missense	distal	3	no	3.389	3.236	EPSD	COSMIC	3.158	Down-regulation
CMGC_CDK_CDC2_CDK1_ST	P10275	AR	P06493	CDK1	S310	D305N	305	Missense	distal	-5	no	3.685	3.689	PhosphoSitePlus;EPSD	COSMIC	3.158	Up-regulation
CMGC_CDK_CDC2_CDK1_ST	P10275	AR	P06493	CDK1	S310	S310F	310	Missense	central	0	yes	3.685	0.000	PhosphoSitePlus;EPSD	COSMIC	3.158	Loss
CMGC_CDK_CDC2_CDK1_ST	P10275	AR	P06493	CDK1	S310	E304K	304	Missense	distal	-6	no	3.685	3.687	PhosphoSitePlus;EPSD	COSMIC	3.158	Up-regulation
CMGC_CDK_CDC2_CDK1_ST	P10275	AR	P06493	CDK1	S310	T306I	306	Missense	distal	-4	no	3.685	3.533	PhosphoSitePlus;EPSD	COSMIC;GDSC;CCLE	3.158	Down-regulation
CMGC_CDK_CDC2_CDK1_ST	P10275	AR	P06493	CDK1	S426	A430T	430	Missense	distal	4	no	3.417	3.365	EPSD	COSMIC	3.158	Down-regulation
CMGC_CDK_CDC2_CDK1_ST	P10275	AR	P06493	CDK1	S426	A420E	420	Missense	distal	-6	no	3.417	3.428	EPSD	COSMIC	3.158	Up-regulation
CMGC_CDK_CDC2_CDK1_ST	P10275	AR	P06493	CDK1	S426	G421V	421	Missense	distal	-5	no	3.417	3.407	EPSD	COSMIC	3.158	Down-regulation
CMGC_CDK_CDC2_CDK1_ST	P10275	AR	P06493	CDK1	S426	A430S	430	Missense	distal	4	no	3.417	3.357	EPSD	COSMIC	3.158	Down-regulation
CMGC_CDK_CDC2_CDK1_ST	P10275	AR	P06493	CDK1	S426	G421R	421	Missense	distal	-5	no	3.417	3.348	EPSD	COSMIC	3.158	Down-regulation
CMGC_CDK_CDC2_CDK1_ST	P10275	AR	P06493	CDK1	S426	S433L	433	Missense	distal	7	no	3.417	3.447	EPSD	COSMIC	3.158	Up-regulation
CMGC_CDK_CDC2_CDK1_ST	P10275	AR	P06493	CDK1	S426	S424C	424	Missense	proximal	-2	no	3.417	3.433	EPSD	COSMIC	3.158	Up-regulation
CMGC_CDK_CDC2_CDK1_ST	P10275	AR	P06493	CDK1	S426	S424F	424	Missense	proximal	-2	no	3.417	3.484	EPSD	COSMIC	3.158	Up-regulation
CMGC_CDK_CDC2_CDK1_ST	P10275	AR	P06493	CDK1	S516	P515H	515	Missense	proximal	-1	no	3.208	3.242	EPSD;PhosphoSitePlus	COSMIC	3.158	Up-regulation
CMGC_CDK_CDC2_CDK1_ST	P10275	AR	P06493	CDK1	S516	E523K	523	Missense	distal	7	no	3.208	3.204	EPSD;PhosphoSitePlus	COSMIC	3.158	Down-regulation
CMGC_CDK_CDC2_CDK1_ST	P10275	AR	P06493	CDK1	S516	P515S	515	Missense	proximal	-1	no	3.208	3.156	EPSD;PhosphoSitePlus	COSMIC	3.158	Loss
CMGC_CDK_CDC2_CDK1_ST	Q14CS0	UBXN2B	P06493	CDK1	S235	P233S	233	Missense	proximal	-2	no	3.415	3.541	EPSD	COSMIC	3.158	Up-regulation
CMGC_CDK_CDC2_CDK1_ST	Q9BPX3	NCAPG	P06493	CDK1	T332	T330I	330	Missense	proximal	-2	no	3.510	3.643	EPSD;PhosphoSitePlus	COSMIC	3.158	Up-regulation
CMGC_CDK_CDC2_CDK1_ST	Q14739	LBR	P06493	CDK1	T200	T196A	196	Missense	distal	-4	no	4.788	4.752	EPSD	COSMIC	3.158	Down-regulation
CMGC_CDK_CDC2_CDK1_ST	Q14739	LBR	P06493	CDK1	T200	P201L	201	Missense	proximal	1	no	4.788	1.101	EPSD	COSMIC	3.158	Loss
CMGC_CDK_CDC2_CDK1_ST	Q14739	LBR	P06493	CDK1	T200	R203W	203	Missense	distal	3	no	4.788	4.659	EPSD	COSMIC	3.158	Down-regulation
CMGC_CDK_CDC2_CDK1_ST	Q14739	LBR	P06493	CDK1	T200	P201S	201	Missense	proximal	1	no	4.788	1.603	EPSD	COSMIC	3.158	Loss
CMGC_CDK_CDC2_CDK1_ST	Q13541	EIF4EBP1	P06493	CDK1	S101	R106L	106	Missense	distal	5	no	3.115	3.338	EPSD	COSMIC	3.158	Gain
CMGC_CDK_CDC2_CDK1_ST	Q9UNZ2	NSFL1C	P06493	CDK1	S114	D121N	121	Missense	distal	7	no	3.194	3.188	EPSD	COSMIC	3.158	Down-regulation
CMGC_CDK_CDC2_CDK1_ST	Q9UNZ2	NSFL1C	P06493	CDK1	S114	P109S	109	Missense	distal	-5	no	3.194	3.171	EPSD	COSMIC	3.158	Down-regulation
CMGC_CDK_CDC2_CDK1_ST	Q02750	MAP2K1	P06493	CDK1	S231	Y229H	229	Missense	proximal	-2	no	3.451	3.421	EPSD	COSMIC	3.158	Down-regulation
CMGC_CDK_CDC2_CDK1_ST	Q02750	MAP2K1	P06493	CDK1	T286	A283V	283	Missense	distal	-3	no	3.180	3.119	PhosphoSitePlus;EPSD	COSMIC	3.158	Loss
CMGC_CDK_CDC2_CDK1_ST	Q02750	MAP2K1	P06493	CDK1	T286	P293S	293	Missense	distal	7	no	3.180	3.178	PhosphoSitePlus;EPSD	COSMIC	3.158	Down-regulation
CMGC_CDK_CDC2_CDK1_ST	Q02750	MAP2K1	P06493	CDK1	T286	R291K	291	Missense	distal	5	no	3.180	3.222	PhosphoSitePlus;EPSD	COSMIC	3.158	Up-regulation
CMGC_CDK_CDC2_CDK1_ST	Q02750	MAP2K1	P06493	CDK1	T292	P293S	293	Missense	proximal	1	no	3.399	0.214	EPSD;PhosphoSitePlus	COSMIC	3.158	Loss
CMGC_CDK_CDC2_CDK1_ST	Q02750	MAP2K1	P06493	CDK1	T292	R291K	291	Missense	proximal	-1	no	3.399	3.469	EPSD;PhosphoSitePlus	COSMIC	3.158	Up-regulation
CMGC_CDK_CDC2_CDK1_ST	P27816	MAP4	P06493	CDK1	S14	D16V	16	Missense	proximal	2	no	3.613	3.620	EPSD	COSMIC	3.158	Up-regulation
CMGC_CDK_CDC2_CDK1_ST	P27816	MAP4	P06493	CDK1	S280	S280L	280	Missense	central	0	yes	3.615	0.000	EPSD	COSMIC	3.158	Loss
CMGC_CDK_CDC2_CDK1_ST	P27816	MAP4	P06493	CDK1	S384	D389V	389	Missense	distal	5	no	3.415	3.477	EPSD	COSMIC	3.158	Up-regulation
CMGC_CDK_CDC2_CDK1_ST	P27816	MAP4	P06493	CDK1	S384	T380R	380	Missense	distal	-4	no	3.415	3.341	EPSD	COSMIC	3.158	Down-regulation
CMGC_CDK_CDC2_CDK1_ST	P27816	MAP4	P06493	CDK1	S384	K378N	378	Missense	distal	-6	no	3.415	3.413	EPSD	COSMIC	3.158	Down-regulation
CMGC_CDK_CDC2_CDK1_ST	P27816	MAP4	P06493	CDK1	T571	P572L	572	Missense	proximal	1	no	3.328	-0.358	EPSD	COSMIC	3.158	Loss
CMGC_CDK_CDC2_CDK1_ST	P27816	MAP4	P06493	CDK1	T571	T571K	571	Missense	central	0	yes	3.328	0.000	EPSD	COSMIC	3.158	Loss
CMGC_CDK_CDC2_CDK1_ST	Q8IX90	SKA3	P06493	CDK1	T190	P192S	192	Missense	proximal	2	no	3.325	3.323	EPSD	COSMIC	3.158	Down-regulation
CMGC_CDK_CDC2_CDK1_ST	O60610	DIAPH1	P06493	CDK1	S22	R21H	21	Missense	proximal	-1	no	3.588	3.611	EPSD	COSMIC	3.158	Up-regulation
CMGC_CDK_CDC2_CDK1_ST	O60610	DIAPH1	P06493	CDK1	S22	R21C	21	Missense	proximal	-1	no	3.588	3.642	EPSD	COSMIC	3.158	Up-regulation
CMGC_CDK_CDC2_CDK1_ST	O60610	DIAPH1	P06493	CDK1	S22	R21L	21	Missense	proximal	-1	no	3.588	3.727	EPSD	COSMIC	3.158	Up-regulation
CMGC_CDK_CDC2_CDK1_ST	O60610	DIAPH1	P06493	CDK1	S22	S22F	22	Missense	central	0	yes	3.588	0.000	EPSD	COSMIC	3.158	Loss
CMGC_CDK_CDC2_CDK1_ST	O60610	DIAPH1	P06493	CDK1	S22	K17N	17	Missense	distal	-5	no	3.588	3.551	EPSD	COSMIC	3.158	Down-regulation
CMGC_CDK_CDC2_CDK1_ST	O60610	DIAPH1	P06493	CDK1	T768	L767I	767	Missense	proximal	-1	no	3.179	3.176	PhosphoSitePlus	COSMIC	3.158	Down-regulation
CMGC_CDK_CDC2_CDK1_ST	Q12959	DLG1	P06493	CDK1	T115	I121V	121	Missense	distal	6	no	3.222	3.234	EPSD	COSMIC	3.158	Up-regulation
CMGC_CDK_CDC2_CDK1_ST	Q12959	DLG1	P06493	CDK1	T115	D114N	114	Missense	proximal	-1	no	3.222	3.227	EPSD	COSMIC	3.158	Up-regulation
CMGC_CDK_CDC2_CDK1_ST	Q12959	DLG1	P06493	CDK1	S122	I121V	121	Missense	proximal	-1	no	3.534	3.482	EPSD	COSMIC	3.158	Down-regulation
CMGC_CDK_CDC2_CDK1_ST	Q12959	DLG1	P06493	CDK1	S158	I160V	160	Missense	proximal	2	no	3.415	3.410	EPSD;PhosphoSitePlus	COSMIC;CCLE	3.158	Down-regulation
CMGC_CDK_CDC2_CDK1_ST	Q12959	DLG1	P06493	CDK1	S448	A453V	453	Missense	distal	5	no	3.218	3.425	EPSD	COSMIC	3.158	Up-regulation
CMGC_CDK_CDC2_CDK1_ST	Q12959	DLG1	P06493	CDK1	S448	V454I	454	Missense	distal	6	no	3.218	3.206	EPSD	COSMIC;GDSC;CCLE	3.158	Down-regulation
CMGC_CDK_CDC2_CDK1_ST	Q12959	DLG1	P06493	CDK1	S448	L455I	455	Missense	distal	7	no	3.218	3.214	EPSD	COSMIC	3.158	Down-regulation
CMGC_CDK_CDC2_CDK1_ST	Q12959	DLG1	P06493	CDK1	T630	T630K	630	Missense	central	0	yes	3.342	0.000	EPSD	COSMIC	3.158	Loss
CMGC_CDK_CDC2_CDK1_ST	Q12959	DLG1	P06493	CDK1	T630	T630I	630	Missense	central	0	yes	3.342	0.000	EPSD	COSMIC	3.158	Loss
CMGC_CDK_CDC2_CDK1_ST	Q12959	DLG1	P06493	CDK1	T630	G633C	633	Missense	distal	3	no	3.342	3.415	EPSD	COSMIC	3.158	Up-regulation
CMGC_CDK_CDC2_CDK1_ST	Q12959	DLG1	P06493	CDK1	T630	G633V	633	Missense	distal	3	no	3.342	3.364	EPSD	COSMIC	3.158	Up-regulation
CMGC_CDK_CDC2_CDK1_ST	Q12959	DLG1	P06493	CDK1	T630	D636N	636	Missense	distal	6	no	3.342	3.350	EPSD	COSMIC	3.158	Up-regulation
CMGC_CDK_CDC2_CDK1_ST	P42898	MTHFR	P06493	CDK1	T34	P35L	35	Missense	proximal	1	no	3.355	-0.331	PhosphoSitePlus	COSMIC	3.158	Loss
CMGC_CDK_CDC2_CDK1_ST	P42898	MTHFR	P06493	CDK1	T34	P39H	39	Missense	distal	5	no	3.355	3.382	PhosphoSitePlus	COSMIC	3.158	Up-regulation
CMGC_CDK_CDC2_CDK1_ST	P42898	MTHFR	P06493	CDK1	T34	R41Q	41	Missense	distal	7	no	3.355	3.351	PhosphoSitePlus	COSMIC	3.158	Down-regulation
CMGC_CDK_CDC2_CDK1_ST	P42898	MTHFR	P06493	CDK1	T34	G36D	36	Missense	proximal	2	no	3.355	3.342	PhosphoSitePlus	COSMIC	3.158	Down-regulation
CMGC_CDK_CDC2_CDK1_ST	Q9UPU5	USP24	P06493	CDK1	T1289	R1296Q	1296	Missense	distal	7	no	3.567	3.563	EPSD	COSMIC	3.158	Down-regulation
CMGC_CDK_CDC2_CDK1_ST	Q9UPU5	USP24	P06493	CDK1	S1943	L1950I	1950	Missense	distal	7	no	3.195	3.191	EPSD	COSMIC	3.158	Down-regulation
CMGC_CDK_CDC2_CDK1_ST	Q9UPU5	USP24	P06493	CDK1	S1943	L1950P	1950	Missense	distal	7	no	3.195	3.167	EPSD	COSMIC	3.158	Down-regulation
CMGC_CDK_CDC2_CDK1_ST	Q9UPU5	USP24	P06493	CDK1	S1943	G1940S	1940	Missense	distal	-3	no	3.195	3.249	EPSD	COSMIC	3.158	Up-regulation
CMGC_CDK_CDC2_CDK1_ST	Q9UPU5	USP24	P06493	CDK1	S1943	S1943F	1943	Missense	central	0	yes	3.195	0.000	EPSD	COSMIC	3.158	Loss
CMGC_CDK_CDC2_CDK1_ST	Q9UPU5	USP24	P06493	CDK1	S1943	G1942E	1942	Missense	proximal	-1	no	3.195	3.068	EPSD	COSMIC	3.158	Loss
CMGC_CDK_CDC2_CDK1_ST	Q9UPU5	USP24	P06493	CDK1	S1943	P1944L	1944	Missense	proximal	1	no	3.195	-0.491	EPSD	COSMIC	3.158	Loss
CMGC_CDK_CDC2_CDK1_ST	Q9UPU5	USP24	P06493	CDK1	S2047	S2047F	2047	Missense	central	0	yes	3.218	0.000	EPSD;PhosphoSitePlus	COSMIC	3.158	Loss
CMGC_CDK_CDC2_CDK1_ST	Q9UPU5	USP24	P06493	CDK1	S2047	R2041K	2041	Missense	distal	-6	no	3.218	3.221	EPSD;PhosphoSitePlus	COSMIC	3.158	Up-regulation
CMGC_CDK_CDC2_CDK1_ST	Q9UPU5	USP24	P06493	CDK1	S2077	P2078S	2078	Missense	proximal	1	no	3.223	0.039	EPSD	COSMIC	3.158	Loss
CMGC_CDK_CDC2_CDK1_ST	Q9UPU5	USP24	P06493	CDK1	S2077	S2072F	2072	Missense	distal	-5	no	3.223	3.333	EPSD	COSMIC	3.158	Up-regulation
CMGC_CDK_CDC2_CDK1_ST	Q9UPU5	USP24	P06493	CDK1	S2081	N2088S	2088	Missense	distal	7	no	3.333	3.325	EPSD	COSMIC	3.158	Down-regulation
CMGC_CDK_CDC2_CDK1_ST	Q9UPU5	USP24	P06493	CDK1	S2081	R2086K	2086	Missense	distal	5	no	3.333	3.375	EPSD	COSMIC	3.158	Up-regulation
CMGC_CDK_CDC2_CDK1_ST	Q9UPU5	USP24	P06493	CDK1	S2081	P2087L	2087	Missense	distal	6	no	3.333	3.277	EPSD	COSMIC	3.158	Down-regulation
CMGC_CDK_CDC2_CDK1_ST	P24928	POLR2A	P06493	CDK1	T368	T365I	365	Missense	distal	-3	no	3.522	3.477	EPSD	COSMIC	3.158	Down-regulation
CMGC_CDK_CDC2_CDK1_ST	P24928	POLR2A	P06493	CDK1	T368	R364C	364	Missense	distal	-4	no	3.522	3.453	EPSD	COSMIC	3.158	Down-regulation
CMGC_CDK_CDC2_CDK1_ST	Q8N122	RPTOR	P06493	CDK1	S877	A874V	874	Missense	distal	-3	no	3.669	3.607	EPSD	COSMIC;GDSC;CCLE	3.158	Down-regulation
CMGC_CDK_CDC2_CDK1_ST	Q8N122	RPTOR	P06493	CDK1	S877	P878S	878	Missense	proximal	1	no	3.669	0.485	EPSD	COSMIC	3.158	Loss
CMGC_CDK_CDC2_CDK1_ST	Q8N122	RPTOR	P06493	CDK1	S877	P879S	879	Missense	proximal	2	no	3.669	3.667	EPSD	COSMIC	3.158	Down-regulation
CMGC_CDK_CDC2_CDK1_ST	Q8N122	RPTOR	P06493	CDK1	S877	A880S	880	Missense	distal	3	no	3.669	3.616	EPSD	COSMIC	3.158	Down-regulation
CMGC_CDK_CDC2_CDK1_ST	Q8N122	RPTOR	P06493	CDK1	S877	P878L	878	Missense	proximal	1	no	3.669	-0.017	EPSD	COSMIC	3.158	Loss
CMGC_CDK_CDC2_CDK1_ST	Q96RL1	UIMC1	P06493	CDK1	S463	I469M	469	Missense	distal	6	no	3.281	3.308	EPSD	COSMIC	3.158	Up-regulation
CMGC_CDK_CDC2_CDK1_ST	Q53EZ4	CEP55	P06493	CDK1	S428	L433P	433	Missense	distal	5	no	3.623	3.438	EPSD;PhosphoSitePlus	COSMIC	3.158	Down-regulation
CMGC_CDK_CDC2_CDK1_ST	Q53EZ4	CEP55	P06493	CDK1	S428	E435G	435	Missense	distal	7	no	3.623	3.636	EPSD;PhosphoSitePlus	COSMIC	3.158	Up-regulation
CMGC_CDK_CDC2_CDK1_ST	Q53EZ4	CEP55	P06493	CDK1	S428	A424T	424	Missense	distal	-4	no	3.623	3.658	EPSD;PhosphoSitePlus	COSMIC	3.158	Up-regulation
CMGC_CDK_CDC2_CDK1_ST	P50613	CDK7	P06493	CDK1	T110	S106I	106	Missense	distal	-4	no	3.186	3.043	EPSD	COSMIC	3.158	Loss
CMGC_CDK_CDC2_CDK1_ST	P50613	CDK7	P06493	CDK1	S164	S161F	161	Missense	distal	-3	no	3.375	3.348	EPSD;PhosphoSitePlus	COSMIC	3.158	Down-regulation
CMGC_CDK_CDC2_CDK1_ST	P50613	CDK7	P06493	CDK1	S164	G163W	163	Missense	proximal	-1	no	3.375	3.289	EPSD;PhosphoSitePlus	COSMIC	3.158	Down-regulation
CMGC_CDK_CDC2_CDK1_ST	P50613	CDK7	P06493	CDK1	S164	S161Y	161	Missense	distal	-3	no	3.375	3.343	EPSD;PhosphoSitePlus	COSMIC	3.158	Down-regulation
CMGC_CDK_CDC2_CDK1_ST	P50613	CDK7	P06493	CDK1	S164	A159D	159	Missense	distal	-5	no	3.375	3.443	EPSD;PhosphoSitePlus	COSMIC	3.158	Up-regulation
CMGC_CDK_CDC2_CDK1_ST	P50613	CDK7	P06493	CDK1	T231	Q236H	236	Missense	distal	5	no	3.153	3.194	EPSD	COSMIC	3.158	Gain
CMGC_CDK_CDC2_CDK1_ST	Q14C86	GAPVD1	P06493	CDK1	S66	A65V	65	Missense	proximal	-1	no	3.873	4.073	EPSD	COSMIC;CCLE	3.158	Up-regulation
CMGC_CDK_CDC2_CDK1_ST	Q14C86	GAPVD1	P06493	CDK1	S66	I60T	60	Missense	distal	-6	no	3.873	3.849	EPSD	COSMIC	3.158	Down-regulation
CMGC_CDK_CDC2_CDK1_ST	Q14C86	GAPVD1	P06493	CDK1	S66	E64K	64	Missense	proximal	-2	no	3.873	3.902	EPSD	COSMIC	3.158	Up-regulation
CMGC_CDK_CDC2_CDK1_ST	Q14C86	GAPVD1	P06493	CDK1	S227	E224Q	224	Missense	distal	-3	no	3.723	3.745	EPSD	COSMIC	3.158	Up-regulation
CMGC_CDK_CDC2_CDK1_ST	Q14C86	GAPVD1	P06493	CDK1	S227	I223N	223	Missense	distal	-4	no	3.723	3.794	EPSD	COSMIC	3.158	Up-regulation
CMGC_CDK_CDC2_CDK1_ST	Q14C86	GAPVD1	P06493	CDK1	T390	S395P	395	Missense	distal	5	no	3.188	3.216	EPSD	COSMIC	3.158	Up-regulation
CMGC_CDK_CDC2_CDK1_ST	Q14C86	GAPVD1	P06493	CDK1	T390	P391S	391	Missense	proximal	1	no	3.188	0.003	EPSD	COSMIC	3.158	Loss
CMGC_CDK_CDC2_CDK1_ST	Q14C86	GAPVD1	P06493	CDK1	S394	S395P	395	Missense	proximal	1	no	0.472	3.657	EPSD	COSMIC	3.158	Gain
CMGC_CDK_CDC2_CDK1_ST	Q14C86	GAPVD1	P06493	CDK1	S801	G794V	794	Missense	distal	-7	no	3.215	3.248	EPSD	COSMIC	3.158	Up-regulation
CMGC_CDK_CDC2_CDK1_ST	Q14C86	GAPVD1	P06493	CDK1	T1389	P1390L	1390	Missense	proximal	1	no	3.666	-0.020	EPSD	COSMIC	3.158	Loss
CMGC_CDK_CDC2_CDK1_ST	Q14C86	GAPVD1	P06493	CDK1	T1389	C1396S	1396	Missense	distal	7	no	3.666	3.651	EPSD	COSMIC	3.158	Down-regulation
CMGC_CDK_CDC2_CDK1_ST	Q14C86	GAPVD1	P06493	CDK1	T1389	T1389P	1389	Missense	central	0	yes	3.666	0.000	EPSD	COSMIC	3.158	Loss
CMGC_CDK_CDC2_CDK1_ST	Q14C86	GAPVD1	P06493	CDK1	T1389	S1385N	1385	Missense	distal	-4	no	3.666	3.594	EPSD	COSMIC	3.158	Down-regulation
CMGC_CDK_CDC2_CDK1_ST	P06748	NPM1	P06493	CDK1	S10	R13S	13	Missense	distal	3	no	3.465	3.394	EPSD	COSMIC	3.158	Down-regulation
CMGC_CDK_CDC2_CDK1_ST	P06748	NPM1	P06493	CDK1	S10	P14L	14	Missense	distal	4	no	3.465	3.343	EPSD	COSMIC	3.158	Down-regulation
CMGC_CDK_CDC2_CDK1_ST	P06748	NPM1	P06493	CDK1	S70	G69D	69	Missense	proximal	-1	no	3.554	3.419	PhosphoSitePlus;EPSD	COSMIC;GDSC;CCLE	3.158	Down-regulation
CMGC_CDK_CDC2_CDK1_ST	P06748	NPM1	P06493	CDK1	T95	V98L	98	Missense	distal	3	no	3.457	3.374	EPSD	COSMIC	3.158	Down-regulation
CMGC_CDK_CDC2_CDK1_ST	P06748	NPM1	P06493	CDK1	T219	G224R	224	Missense	distal	5	no	3.192	3.000	EPSD;PhosphoSitePlus	COSMIC	3.158	Loss
CMGC_CDK_CDC2_CDK1_ST	Q9Y2I6	NINL	P06493	CDK1	S185	P186L	186	Missense	proximal	1	no	3.334	-0.353	EPSD;PhosphoSitePlus	COSMIC	3.158	Loss
CMGC_CDK_CDC2_CDK1_ST	Q9Y2I6	NINL	P06493	CDK1	S191	P186L	186	Missense	distal	-5	no	3.114	3.235	EPSD	COSMIC	3.158	Gain
CMGC_CDK_CDC2_CDK1_ST	Q9Y2I6	NINL	P06493	CDK1	S589	R595W	595	Missense	distal	6	no	3.199	3.161	PhosphoSitePlus;EPSD	COSMIC	3.158	Down-regulation
CMGC_CDK_CDC2_CDK1_ST	Q9Y2I6	NINL	P06493	CDK1	S589	S589N	589	Missense	central	0	yes	3.199	0.000	PhosphoSitePlus;EPSD	COSMIC	3.158	Loss
CMGC_CDK_CDC2_CDK1_ST	Q9Y2I6	NINL	P06493	CDK1	S589	N582I	582	Missense	distal	-7	no	3.199	3.106	PhosphoSitePlus;EPSD	COSMIC	3.158	Loss
CMGC_CDK_CDC2_CDK1_ST	Q9Y2I6	NINL	P06493	CDK1	S589	P590S	590	Missense	proximal	1	no	3.199	0.014	PhosphoSitePlus;EPSD	COSMIC	3.158	Loss
CMGC_CDK_CDC2_CDK1_ST	Q8NHV4	NEDD1	P06493	CDK1	S215	N218D	218	Missense	distal	3	no	3.314	3.240	EPSD	COSMIC	3.158	Down-regulation
CMGC_CDK_CDC2_CDK1_ST	Q8NHV4	NEDD1	P06493	CDK1	S282	L280F	280	Missense	proximal	-2	no	3.636	3.657	EPSD	COSMIC	3.158	Up-regulation
CMGC_CDK_CDC2_CDK1_ST	Q8NHV4	NEDD1	P06493	CDK1	S411	P412L	412	Missense	proximal	1	no	3.989	0.303	EPSD;PhosphoSitePlus	COSMIC	3.158	Loss
CMGC_CDK_CDC2_CDK1_ST	Q9BTA9	WAC	P06493	CDK1	S53	G50A	50	Missense	distal	-3	no	3.065	3.161	EPSD	COSMIC;GDSC;CCLE	3.158	Gain
CMGC_CDK_CDC2_CDK1_ST	Q9BTA9	WAC	P06493	CDK1	S64	K57N	57	Missense	distal	-7	no	3.405	3.457	EPSD	COSMIC	3.158	Up-regulation
CMGC_CDK_CDC2_CDK1_ST	Q9BTA9	WAC	P06493	CDK1	S64	D63N	63	Missense	proximal	-1	no	3.405	3.410	EPSD	COSMIC;GDSC;CCLE	3.158	Up-regulation
CMGC_CDK_CDC2_CDK1_ST	Q9BTA9	WAC	P06493	CDK1	S64	S64N	64	Missense	central	0	yes	3.405	0.000	EPSD	COSMIC	3.158	Loss
CMGC_CDK_CDC2_CDK1_ST	Q9BTA9	WAC	P06493	CDK1	T293	P292L	292	Missense	proximal	-1	no	3.056	3.206	EPSD	COSMIC	3.158	Gain
CMGC_CDK_CDC2_CDK1_ST	Q9BTA9	WAC	P06493	CDK1	S346	P344S	344	Missense	proximal	-2	no	4.360	4.487	EPSD	COSMIC	3.158	Up-regulation
CMGC_CDK_CDC2_CDK1_ST	Q9BTA9	WAC	P06493	CDK1	S346	P347L	347	Missense	proximal	1	no	4.360	0.674	EPSD	COSMIC	3.158	Loss
CMGC_CDK_CDC2_CDK1_ST	Q9BTA9	WAC	P06493	CDK1	S346	S341L	341	Missense	distal	-5	no	4.360	4.504	EPSD	COSMIC	3.158	Up-regulation
CMGC_CDK_CDC2_CDK1_ST	Q9BTA9	WAC	P06493	CDK1	S346	S339P	339	Missense	distal	-7	no	4.360	4.320	EPSD	COSMIC	3.158	Down-regulation
CMGC_CDK_CDC2_CDK1_ST	Q9BTA9	WAC	P06493	CDK1	S351	P344S	344	Missense	distal	-7	no	3.324	3.365	EPSD	COSMIC	3.158	Up-regulation
CMGC_CDK_CDC2_CDK1_ST	Q9BTA9	WAC	P06493	CDK1	S351	P355T	355	Missense	distal	4	no	3.324	3.329	EPSD	COSMIC	3.158	Up-regulation
CMGC_CDK_CDC2_CDK1_ST	Q9BTA9	WAC	P06493	CDK1	S351	P347L	347	Missense	distal	-4	no	3.324	3.181	EPSD	COSMIC	3.158	Down-regulation
CMGC_CDK_CDC2_CDK1_ST	Q9BTA9	WAC	P06493	CDK1	T482	S481T	481	Missense	proximal	-1	no	3.307	3.281	PhosphoSitePlus;EPSD	COSMIC	3.158	Down-regulation
CMGC_CDK_CDC2_CDK1_ST	Q9BTA9	WAC	P06493	CDK1	T482	P483T	483	Missense	proximal	1	no	3.307	0.874	PhosphoSitePlus;EPSD	COSMIC	3.158	Loss
CMGC_CDK_CDC2_CDK1_ST	Q9BTA9	WAC	P06493	CDK1	T482	S475L	475	Missense	distal	-7	no	3.307	3.107	PhosphoSitePlus;EPSD	COSMIC	3.158	Loss
CMGC_CDK_CDC2_CDK1_ST	Q9BTA9	WAC	P06493	CDK1	T556	A558S	558	Missense	proximal	2	no	3.210	3.217	EPSD	COSMIC	3.158	Up-regulation
CMGC_CDK_CDC2_CDK1_ST	Q9BTA9	WAC	P06493	CDK1	T556	T552M	552	Missense	distal	-4	no	3.210	3.121	EPSD	COSMIC	3.158	Loss
CMGC_CDK_CDC2_CDK1_ST	Q9BTA9	WAC	P06493	CDK1	T556	T552A	552	Missense	distal	-4	no	3.210	3.175	EPSD	COSMIC	3.158	Down-regulation
CMGC_CDK_CDC2_CDK1_ST	Q96PY5	FMNL2	P06493	CDK1	S1016	S1016F	1016	Missense	central	0	yes	3.430	0.000	EPSD;PhosphoSitePlus	COSMIC;GDSC	3.158	Loss
CMGC_CDK_CDC2_CDK1_ST	Q14157	UBAP2L	P06493	CDK1	S477	S475T	475	Missense	proximal	-2	no	3.457	3.418	EPSD	COSMIC	3.158	Down-regulation
CMGC_CDK_CDC2_CDK1_ST	Q14157	UBAP2L	P06493	CDK1	S477	P480S	480	Missense	distal	3	no	3.457	3.507	EPSD	COSMIC;GDSC;CCLE	3.158	Up-regulation
CMGC_CDK_CDC2_CDK1_ST	Q14157	UBAP2L	P06493	CDK1	S477	S477R	477	Missense	central	0	yes	3.457	0.000	EPSD	COSMIC	3.158	Loss
CMGC_CDK_CDC2_CDK1_ST	Q14157	UBAP2L	P06493	CDK1	S477	S470R	470	Missense	distal	-7	no	3.457	3.421	EPSD	COSMIC	3.158	Down-regulation
CMGC_CDK_CDC2_CDK1_ST	Q14157	UBAP2L	P06493	CDK1	S609	S607Y	607	Missense	proximal	-2	no	3.119	3.170	EPSD	COSMIC	3.158	Gain
CMGC_CDK_CDC2_CDK1_ST	Q8NCD3	HJURP	P06493	CDK1	T380	R377C	377	Missense	distal	-3	no	3.423	3.434	EPSD	COSMIC	3.158	Up-regulation
CMGC_CDK_CDC2_CDK1_ST	Q8NCD3	HJURP	P06493	CDK1	T380	R377H	377	Missense	distal	-3	no	3.423	3.434	EPSD	COSMIC	3.158	Up-regulation
CMGC_CDK_CDC2_CDK1_ST	Q8NCD3	HJURP	P06493	CDK1	T380	K375N	375	Missense	distal	-5	no	3.423	3.387	EPSD	COSMIC	3.158	Down-regulation
CMGC_CDK_CDC2_CDK1_ST	Q8NCD3	HJURP	P06493	CDK1	S412	K408R	408	Missense	distal	-4	no	3.583	3.630	EPSD;PhosphoSitePlus	COSMIC	3.158	Up-regulation
CMGC_CDK_CDC2_CDK1_ST	Q8NCD3	HJURP	P06493	CDK1	S412	K408N	408	Missense	distal	-4	no	3.583	3.623	EPSD;PhosphoSitePlus	COSMIC	3.158	Up-regulation
CMGC_CDK_CDC2_CDK1_ST	Q8NCD3	HJURP	P06493	CDK1	S412	R405M	405	Missense	distal	-7	no	3.583	3.551	EPSD;PhosphoSitePlus	COSMIC;GDSC;CCLE	3.158	Down-regulation
CMGC_CDK_CDC2_CDK1_ST	Q8NCD3	HJURP	P06493	CDK1	S412	I411M	411	Missense	proximal	-1	no	3.583	3.473	EPSD;PhosphoSitePlus	COSMIC	3.158	Down-regulation
CMGC_CDK_CDC2_CDK1_ST	Q8NCD3	HJURP	P06493	CDK1	S412	S412Y	412	Missense	central	0	yes	3.583	0.000	EPSD;PhosphoSitePlus	COSMIC	3.158	Loss
CMGC_CDK_CDC2_CDK1_ST	Q8NCD3	HJURP	P06493	CDK1	S557	G550R	550	Missense	distal	-7	no	3.233	3.356	EPSD	COSMIC	3.158	Up-regulation
CMGC_CDK_CDC2_CDK1_ST	P46013	MKI67	P06493	CDK1	S235	N229D	229	Missense	distal	-6	no	3.607	3.609	EPSD	COSMIC	3.158	Up-regulation
CMGC_CDK_CDC2_CDK1_ST	P46013	MKI67	P06493	CDK1	S235	Y241H	241	Missense	distal	6	no	3.607	3.633	EPSD	COSMIC	3.158	Up-regulation
CMGC_CDK_CDC2_CDK1_ST	P46013	MKI67	P06493	CDK1	T328	S330N	330	Missense	proximal	2	no	3.342	3.348	EPSD	COSMIC	3.158	Up-regulation
CMGC_CDK_CDC2_CDK1_ST	P46013	MKI67	P06493	CDK1	T347	T347N	347	Missense	central	0	yes	3.547	0.000	EPSD	COSMIC	3.158	Loss
CMGC_CDK_CDC2_CDK1_ST	P46013	MKI67	P06493	CDK1	T525	P523L	523	Missense	proximal	-2	no	3.101	3.274	EPSD	COSMIC	3.158	Gain
CMGC_CDK_CDC2_CDK1_ST	P46013	MKI67	P06493	CDK1	T1017	P1012L	1012	Missense	distal	-5	no	3.121	3.242	EPSD	COSMIC	3.158	Gain
CMGC_CDK_CDC2_CDK1_ST	P46013	MKI67	P06493	CDK1	S1071	R1066T	1066	Missense	distal	-5	no	3.302	3.242	EPSD	COSMIC	3.158	Down-regulation
CMGC_CDK_CDC2_CDK1_ST	P46013	MKI67	P06493	CDK1	S1071	F1068L	1068	Missense	distal	-3	no	3.302	3.298	EPSD	COSMIC	3.158	Down-regulation
CMGC_CDK_CDC2_CDK1_ST	P46013	MKI67	P06493	CDK1	S1071	T1067A	1067	Missense	distal	-4	no	3.302	3.267	EPSD	COSMIC	3.158	Down-regulation
CMGC_CDK_CDC2_CDK1_ST	P46013	MKI67	P06493	CDK1	T1176	G1171W	1171	Missense	distal	-5	no	4.400	4.357	EPSD	COSMIC	3.158	Down-regulation
CMGC_CDK_CDC2_CDK1_ST	P46013	MKI67	P06493	CDK1	T1176	D1183N	1183	Missense	distal	7	no	4.400	4.395	EPSD	COSMIC	3.158	Down-regulation
CMGC_CDK_CDC2_CDK1_ST	P46013	MKI67	P06493	CDK1	T1298	T1298M	1298	Missense	central	0	yes	4.246	0.000	EPSD	COSMIC;GDSC	3.158	Loss
CMGC_CDK_CDC2_CDK1_ST	P46013	MKI67	P06493	CDK1	T1298	P1301L	1301	Missense	distal	3	no	4.246	4.113	EPSD	COSMIC	3.158	Down-regulation
CMGC_CDK_CDC2_CDK1_ST	P46013	MKI67	P06493	CDK1	T1298	E1305Q	1305	Missense	distal	7	no	4.246	4.235	EPSD	COSMIC	3.158	Down-regulation
CMGC_CDK_CDC2_CDK1_ST	P46013	MKI67	P06493	CDK1	T1393	V1400L	1400	Missense	distal	7	no	3.158	3.164	EPSD	COSMIC	3.158	Up-regulation
CMGC_CDK_CDC2_CDK1_ST	P46013	MKI67	P06493	CDK1	T1418	H1419P	1419	Missense	proximal	1	no	0.802	3.486	EPSD	COSMIC	3.158	Gain
CMGC_CDK_CDC2_CDK1_ST	P46013	MKI67	P06493	CDK1	T1775	Q1774L	1774	Missense	proximal	-1	no	3.040	3.191	EPSD	COSMIC	3.158	Gain
CMGC_CDK_CDC2_CDK1_ST	P46013	MKI67	P06493	CDK1	T1775	A1770V	1770	Missense	distal	-5	no	3.040	3.180	EPSD	COSMIC	3.158	Gain
CMGC_CDK_CDC2_CDK1_ST	P46013	MKI67	P06493	CDK1	T1784	H1783N	1783	Missense	proximal	-1	no	3.745	3.750	EPSD	COSMIC	3.158	Up-regulation
CMGC_CDK_CDC2_CDK1_ST	P46013	MKI67	P06493	CDK1	T1784	A1778V	1778	Missense	distal	-6	no	3.745	3.767	EPSD	COSMIC;GDSC;CCLE	3.158	Up-regulation
CMGC_CDK_CDC2_CDK1_ST	P46013	MKI67	P06493	CDK1	T1784	M1782I	1782	Missense	proximal	-2	no	3.745	3.822	EPSD	COSMIC	3.158	Up-regulation
CMGC_CDK_CDC2_CDK1_ST	P46013	MKI67	P06493	CDK1	T1906	M1904I	1904	Missense	proximal	-2	no	4.274	4.350	EPSD	COSMIC	3.158	Up-regulation
CMGC_CDK_CDC2_CDK1_ST	P46013	MKI67	P06493	CDK1	T1906	G1912C	1912	Missense	distal	6	no	4.274	4.296	EPSD	COSMIC	3.158	Up-regulation
CMGC_CDK_CDC2_CDK1_ST	P46013	MKI67	P06493	CDK1	T1906	A1910E	1910	Missense	distal	4	no	4.274	4.170	EPSD	COSMIC	3.158	Down-regulation
CMGC_CDK_CDC2_CDK1_ST	P46013	MKI67	P06493	CDK1	T1906	T1906M	1906	Missense	central	0	yes	4.274	0.000	EPSD	COSMIC	3.158	Loss
CMGC_CDK_CDC2_CDK1_ST	P46013	MKI67	P06493	CDK1	T1923	T1923I	1923	Missense	central	0	yes	3.161	0.000	EPSD	COSMIC	3.158	Loss
CMGC_CDK_CDC2_CDK1_ST	P46013	MKI67	P06493	CDK1	T1923	V1925A	1925	Missense	proximal	2	no	3.161	3.139	EPSD	COSMIC	3.158	Loss
CMGC_CDK_CDC2_CDK1_ST	P46013	MKI67	P06493	CDK1	T1923	N1918K	1918	Missense	distal	-5	no	3.161	3.198	EPSD	COSMIC	3.158	Up-regulation
CMGC_CDK_CDC2_CDK1_ST	P46013	MKI67	P06493	CDK1	S1983	D1987A	1987	Missense	distal	4	no	3.059	3.163	EPSD	COSMIC	3.158	Gain
CMGC_CDK_CDC2_CDK1_ST	P46013	MKI67	P06493	CDK1	S2105	I2101T	2101	Missense	distal	-4	no	3.063	3.215	EPSD	COSMIC	3.158	Gain
CMGC_CDK_CDC2_CDK1_ST	P46013	MKI67	P06493	CDK1	S2223	R2222K	2222	Missense	proximal	-1	no	3.306	3.376	EPSD	COSMIC	3.158	Up-regulation
CMGC_CDK_CDC2_CDK1_ST	P46013	MKI67	P06493	CDK1	T2268	M2266T	2266	Missense	proximal	-2	no	3.903	3.847	EPSD	COSMIC	3.158	Down-regulation
CMGC_CDK_CDC2_CDK1_ST	P46013	MKI67	P06493	CDK1	T2268	V2262A	2262	Missense	distal	-6	no	3.903	3.882	EPSD	COSMIC	3.158	Down-regulation
CMGC_CDK_CDC2_CDK1_ST	P46013	MKI67	P06493	CDK1	T2268	T2268K	2268	Missense	central	0	yes	3.903	0.000	EPSD	COSMIC	3.158	Loss
CMGC_CDK_CDC2_CDK1_ST	P46013	MKI67	P06493	CDK1	T2268	G2274C	2274	Missense	distal	6	no	3.903	3.926	EPSD	COSMIC	3.158	Up-regulation
CMGC_CDK_CDC2_CDK1_ST	P46013	MKI67	P06493	CDK1	T2268	S2261T	2261	Missense	distal	-7	no	3.903	3.924	EPSD	COSMIC	3.158	Up-regulation
CMGC_CDK_CDC2_CDK1_ST	P46013	MKI67	P06493	CDK1	T2352	A2354T	2354	Missense	proximal	2	no	3.281	3.287	EPSD	COSMIC	3.158	Up-regulation
CMGC_CDK_CDC2_CDK1_ST	P46013	MKI67	P06493	CDK1	T2352	R2359L	2359	Missense	distal	7	no	3.281	3.303	EPSD	COSMIC	3.158	Up-regulation
CMGC_CDK_CDC2_CDK1_ST	P46013	MKI67	P06493	CDK1	T2352	D2348H	2348	Missense	distal	-4	no	3.281	3.269	EPSD	COSMIC	3.158	Down-regulation
CMGC_CDK_CDC2_CDK1_ST	P46013	MKI67	P06493	CDK1	T2352	P2347S	2347	Missense	distal	-5	no	3.281	3.258	EPSD	COSMIC	3.158	Down-regulation
CMGC_CDK_CDC2_CDK1_ST	P46013	MKI67	P06493	CDK1	T2352	S2355N	2355	Missense	distal	3	no	3.281	3.286	EPSD	COSMIC	3.158	Up-regulation
CMGC_CDK_CDC2_CDK1_ST	P46013	MKI67	P06493	CDK1	T2389	P2390S	2390	Missense	proximal	1	no	4.050	0.865	EPSD	COSMIC;GDSC	3.158	Loss
CMGC_CDK_CDC2_CDK1_ST	P46013	MKI67	P06493	CDK1	T2389	T2389R	2389	Missense	central	0	yes	4.050	0.000	EPSD	COSMIC	3.158	Loss
CMGC_CDK_CDC2_CDK1_ST	P46013	MKI67	P06493	CDK1	T2389	D2388H	2388	Missense	proximal	-1	no	4.050	4.051	EPSD	COSMIC	3.158	Up-regulation
CMGC_CDK_CDC2_CDK1_ST	P46013	MKI67	P06493	CDK1	S2528	A2524V	2524	Missense	distal	-4	no	3.238	3.143	EPSD	COSMIC	3.158	Loss
CMGC_CDK_CDC2_CDK1_ST	P46013	MKI67	P06493	CDK1	S2528	E2527D	2527	Missense	proximal	-1	no	3.238	3.230	EPSD	COSMIC;GDSC;CCLE	3.158	Down-regulation
CMGC_CDK_CDC2_CDK1_ST	P46013	MKI67	P06493	CDK1	S2719	T2720P	2720	Missense	proximal	1	no	0.832	3.266	EPSD	COSMIC	3.158	Gain
CMGC_CDK_CDC2_CDK1_ST	Q14790	CASP8	P06493	CDK1	S192	S186N	186	Missense	distal	-6	no	3.426	3.434	EPSD	COSMIC	3.158	Up-regulation
CMGC_CDK_CDC2_CDK1_ST	Q14790	CASP8	P06493	CDK1	S192	S188A	188	Missense	distal	-4	no	3.426	3.399	EPSD	COSMIC	3.158	Down-regulation
CMGC_CDK_CDC2_CDK1_ST	Q14790	CASP8	P06493	CDK1	T221	L222P	222	Missense	proximal	1	no	-0.340	3.346	EPSD	COSMIC	3.158	Gain
CMGC_CDK_CDC2_CDK1_ST	Q14790	CASP8	P06493	CDK1	S387	S386L	386	Missense	proximal	-1	no	3.056	3.258	PhosphoSitePlus	COSMIC	3.158	Gain
CMGC_CDK_CDC2_CDK1_ST	Q5BJF6	ODF2	P06493	CDK1	T92	I91T	91	Missense	proximal	-1	no	3.375	3.149	EPSD	COSMIC;CCLE	3.158	Loss
CMGC_CDK_CDC2_CDK1_ST	Q5BJF6	ODF2	P06493	CDK1	T92	P85A	85	Missense	distal	-7	no	3.375	3.443	EPSD	COSMIC	3.158	Up-regulation
CMGC_CDK_CDC2_CDK1_ST	Q5BJF6	ODF2	P06493	CDK1	T92	E97G	97	Missense	distal	5	no	3.375	3.477	EPSD	COSMIC	3.158	Up-regulation
CMGC_CDK_CDC2_CDK1_ST	Q14005	IL16	P06493	CDK1	T757	T750I	750	Missense	distal	-7	no	3.184	3.011	PhosphoSitePlus	COSMIC	3.158	Loss
CMGC_CDK_CDC2_CDK1_ST	Q14005	IL16	P06493	CDK1	T757	K760M	760	Missense	distal	3	no	3.184	3.092	PhosphoSitePlus	COSMIC	3.158	Loss
CMGC_CDK_CDC2_CDK1_ST	Q14005	IL16	P06493	CDK1	T757	D755Y	755	Missense	proximal	-2	no	3.184	3.216	PhosphoSitePlus	COSMIC	3.158	Up-regulation
CMGC_CDK_CDC2_CDK1_ST	Q14005	IL16	P06493	CDK1	S867	S868P	868	Missense	proximal	1	no	0.034	3.219	EPSD	COSMIC	3.158	Gain
CMGC_CDK_CDC2_CDK1_ST	O94901	SUN1	P06493	CDK1	S48	R50Q	50	Missense	proximal	2	no	3.410	3.406	EPSD;PhosphoSitePlus	COSMIC	3.158	Down-regulation
CMGC_CDK_CDC2_CDK1_ST	Q9UQR0	SCML2	P06493	CDK1	S590	P591S	591	Missense	proximal	1	no	3.218	0.033	EPSD;PhosphoSitePlus	COSMIC	3.158	Loss
CMGC_CDK_CDC2_CDK1_ST	P00533	EGFR	P06493	CDK1	T693	A698V	698	Missense	distal	5	no	3.602	3.809	EPSD	COSMIC	3.158	Up-regulation
CMGC_CDK_CDC2_CDK1_ST	P00533	EGFR	P06493	CDK1	T693	P691T	691	Missense	proximal	-2	no	3.602	3.689	EPSD	COSMIC	3.158	Up-regulation
CMGC_CDK_CDC2_CDK1_ST	P00533	EGFR	P06493	CDK1	T693	L688P	688	Missense	distal	-5	no	3.602	3.481	EPSD	COSMIC	3.158	Down-regulation
CMGC_CDK_CDC2_CDK1_ST	P00533	EGFR	P06493	CDK1	T693	P699S	699	Missense	distal	6	no	3.602	3.609	EPSD	COSMIC	3.158	Up-regulation
CMGC_CDK_CDC2_CDK1_ST	P00533	EGFR	P06493	CDK1	T693	V689M	689	Missense	distal	-4	no	3.602	3.643	EPSD	COSMIC	3.158	Up-regulation
CMGC_CDK_CDC2_CDK1_ST	P00533	EGFR	P06493	CDK1	T693	N700Y	700	Missense	distal	7	no	3.602	3.610	EPSD	COSMIC	3.158	Up-regulation
CMGC_CDK_CDC2_CDK1_ST	P00533	EGFR	P06493	CDK1	T693	L692P	692	Missense	proximal	-1	no	3.602	3.452	EPSD	COSMIC	3.158	Down-regulation
CMGC_CDK_CDC2_CDK1_ST	P00533	EGFR	P06493	CDK1	T693	P694S	694	Missense	proximal	1	no	3.602	0.417	EPSD	COSMIC	3.158	Loss
CMGC_CDK_CDC2_CDK1_ST	P00533	EGFR	P06493	CDK1	T693	N700S	700	Missense	distal	7	no	3.602	3.594	EPSD	COSMIC	3.158	Down-regulation
CMGC_CDK_CDC2_CDK1_ST	P00533	EGFR	P06493	CDK1	T693	E690K	690	Missense	distal	-3	no	3.602	3.590	EPSD	COSMIC	3.158	Down-regulation
CMGC_CDK_CDC2_CDK1_ST	P00533	EGFR	P06493	CDK1	T693	P691S	691	Missense	proximal	-2	no	3.602	3.728	EPSD	COSMIC	3.158	Up-regulation
CMGC_CDK_CDC2_CDK1_ST	P00533	EGFR	P06493	CDK1	T693	V689L	689	Missense	distal	-4	no	3.602	3.529	EPSD	COSMIC	3.158	Down-regulation
CMGC_CDK_CDC2_CDK1_ST	P00533	EGFR	P06493	CDK1	T693	E697D	697	Missense	distal	4	no	3.602	3.601	EPSD	COSMIC	3.158	Down-regulation
CMGC_CDK_CDC2_CDK1_ST	P00533	EGFR	P06493	CDK1	T693	P694L	694	Missense	proximal	1	no	3.602	-0.085	EPSD	COSMIC	3.158	Loss
CMGC_CDK_CDC2_CDK1_ST	P00533	EGFR	P06493	CDK1	T693	L688F	688	Missense	distal	-5	no	3.602	3.568	EPSD	COSMIC	3.158	Down-regulation
CMGC_CDK_CDC2_CDK1_ST	P00533	EGFR	P06493	CDK1	T693	N700D	700	Missense	distal	7	no	3.602	3.607	EPSD	COSMIC	3.158	Up-regulation
CMGC_CDK_CDC2_CDK1_ST	P00533	EGFR	P06493	CDK1	T693	S695G	695	Missense	proximal	2	no	3.602	3.625	EPSD	COSMIC	3.158	Up-regulation
CMGC_CDK_CDC2_CDK1_ST	P00533	EGFR	P06493	CDK1	T693	R686S	686	Missense	distal	-7	no	3.602	3.638	EPSD	COSMIC	3.158	Up-regulation
CMGC_CDK_CDC2_CDK1_ST	P00533	EGFR	P06493	CDK1	T693	T693A	693	Missense	central	0	yes	3.602	0.000	EPSD	COSMIC	3.158	Loss
CMGC_CDK_CDC2_CDK1_ST	P00533	EGFR	P06493	CDK1	T693	E690V	690	Missense	distal	-3	no	3.602	3.609	EPSD	COSMIC	3.158	Up-regulation
CMGC_CDK_CDC2_CDK1_ST	P00533	EGFR	P06493	CDK1	T693	L692F	692	Missense	proximal	-1	no	3.602	3.553	EPSD	COSMIC	3.158	Down-regulation
CMGC_CDK_CDC2_CDK1_ST	P00533	EGFR	P06493	CDK1	T693	G696R	696	Missense	distal	3	no	3.602	3.795	EPSD	COSMIC	3.158	Up-regulation
CMGC_CDK_CDC2_CDK1_ST	P00533	EGFR	P06493	CDK1	T693	G696E	696	Missense	distal	3	no	3.602	3.673	EPSD	COSMIC	3.158	Up-regulation
CMGC_CDK_CDC2_CDK1_ST	P00533	EGFR	P06493	CDK1	S752	T751I	751	Missense	proximal	-1	no	3.109	3.335	EPSD	COSMIC;GDSC;CCLE	3.158	Gain
CMGC_CDK_CDC2_CDK1_ST	P00533	EGFR	P06493	CDK1	S752	A750T	750	Missense	proximal	-2	no	3.109	3.189	EPSD	COSMIC	3.158	Gain
CMGC_CDK_CDC2_CDK1_ST	P00533	EGFR	P06493	CDK1	S752	T751L	751	Missense	proximal	-1	no	3.109	3.338	EPSD	COSMIC	3.158	Gain
CMGC_CDK_CDC2_CDK1_ST	P00533	EGFR	P06493	CDK1	S752	K745R	745	Missense	distal	-7	no	3.109	3.185	EPSD	COSMIC	3.158	Gain
CMGC_CDK_CDC2_CDK1_ST	P00533	EGFR	P06493	CDK1	S752	K745T	745	Missense	distal	-7	no	3.109	3.242	EPSD	COSMIC	3.158	Gain
CMGC_CDK_CDC2_CDK1_ST	P00533	EGFR	P06493	CDK1	S752	T751P	751	Missense	proximal	-1	no	3.109	3.187	EPSD	COSMIC	3.158	Gain
CMGC_CDK_CDC2_CDK1_ST	Q99708	RBBP8	P06493	CDK1	S10	S7R	7	Missense	distal	-3	no	3.676	3.650	EPSD	COSMIC	3.158	Down-regulation
CMGC_CDK_CDC2_CDK1_ST	Q99708	RBBP8	P06493	CDK1	S10	S4L	4	Missense	distal	-6	no	3.676	3.704	EPSD	COSMIC;GDSC;CCLE	3.158	Up-regulation
CMGC_CDK_CDC2_CDK1_ST	Q99708	RBBP8	P06493	CDK1	S568	L564F	564	Missense	distal	-4	no	3.390	3.438	EPSD	COSMIC	3.158	Up-regulation
CMGC_CDK_CDC2_CDK1_ST	Q99708	RBBP8	P06493	CDK1	S889	Q882E	882	Missense	distal	-7	no	3.699	3.662	EPSD	COSMIC	3.158	Down-regulation
CMGC_CDK_CDC2_CDK1_ST	Q16513	PKN2	P06493	CDK1	T958	I956F	956	Missense	proximal	-2	no	3.476	3.450	EPSD	COSMIC	3.158	Down-regulation
CMGC_CDK_CDC2_CDK1_ST	Q16513	PKN2	P06493	CDK1	T958	P955A	955	Missense	distal	-3	no	3.476	3.518	EPSD	COSMIC	3.158	Up-regulation
CMGC_CDK_CDC2_CDK1_ST	Q16513	PKN2	P06493	CDK1	T958	R964K	964	Missense	distal	6	no	3.476	3.451	EPSD	COSMIC	3.158	Down-regulation
CMGC_CDK_CDC2_CDK1_ST	O00562	PITPNM1	P06493	CDK1	S382	I377V	377	Missense	distal	-5	no	3.280	3.267	EPSD;PhosphoSitePlus	COSMIC	3.158	Down-regulation
CMGC_CDK_CDC2_CDK1_ST	O00562	PITPNM1	P06493	CDK1	S382	T389M	389	Missense	distal	7	no	3.280	3.288	EPSD;PhosphoSitePlus	COSMIC	3.158	Up-regulation
CMGC_CDK_CDC2_CDK1_ST	O00562	PITPNM1	P06493	CDK1	T389	G393R	393	Missense	distal	4	no	3.279	3.404	EPSD	COSMIC	3.158	Up-regulation
CMGC_CDK_CDC2_CDK1_ST	O00562	PITPNM1	P06493	CDK1	T389	T389M	389	Missense	central	0	yes	3.279	0.000	EPSD	COSMIC	3.158	Loss
CMGC_CDK_CDC2_CDK1_ST	O00562	PITPNM1	P06493	CDK1	S896	E902D	902	Missense	distal	6	no	3.383	3.381	EPSD	COSMIC	3.158	Down-regulation
CMGC_CDK_CDC2_CDK1_ST	O00562	PITPNM1	P06493	CDK1	S896	E890K	890	Missense	distal	-6	no	3.383	3.385	EPSD	COSMIC	3.158	Up-regulation
CMGC_CDK_CDC2_CDK1_ST	O00562	PITPNM1	P06493	CDK1	S896	S896I	896	Missense	central	0	yes	3.383	0.000	EPSD	COSMIC	3.158	Loss
CMGC_CDK_CDC2_CDK1_ST	O00562	PITPNM1	P06493	CDK1	T1223	R1218H	1218	Missense	distal	-5	no	3.225	3.220	EPSD	COSMIC	3.158	Down-regulation
CMGC_CDK_CDC2_CDK1_ST	O00562	PITPNM1	P06493	CDK1	T1223	E1219G	1219	Missense	distal	-4	no	3.225	3.146	EPSD	COSMIC	3.158	Loss
CMGC_CDK_CDC2_CDK1_ST	Q9Y2V2	CARHSP1	P06493	CDK1	T23	R29C	29	Missense	distal	6	no	3.319	3.282	PhosphoSitePlus	COSMIC	3.158	Down-regulation
CMGC_CDK_CDC2_CDK1_ST	Q9Y2V2	CARHSP1	P06493	CDK1	T23	G19R	19	Missense	distal	-4	no	3.319	3.391	PhosphoSitePlus	COSMIC	3.158	Up-regulation
CMGC_CDK_CDC2_CDK1_ST	Q9Y2V2	CARHSP1	P06493	CDK1	T80	D87Y	87	Missense	distal	7	no	3.594	3.597	EPSD	COSMIC	3.158	Up-regulation
CMGC_CDK_CDC2_CDK1_ST	Q9Y2V2	CARHSP1	P06493	CDK1	T80	D87N	87	Missense	distal	7	no	3.594	3.589	EPSD	COSMIC	3.158	Down-regulation
CMGC_CDK_CDC2_CDK1_ST	O00429	DNM1L	P06493	CDK1	S126	S119L	119	Missense	distal	-7	no	3.395	3.194	EPSD	COSMIC	3.158	Down-regulation
CMGC_CDK_CDC2_CDK1_ST	O00429	DNM1L	P06493	CDK1	S126	K133N	133	Missense	distal	7	no	3.395	3.392	EPSD	COSMIC	3.158	Down-regulation
CMGC_CDK_CDC2_CDK1_ST	O00429	DNM1L	P06493	CDK1	S126	G124E	124	Missense	proximal	-2	no	3.395	3.343	EPSD	COSMIC	3.158	Down-regulation
CMGC_CDK_CDC2_CDK1_ST	O00429	DNM1L	P06493	CDK1	S126	G124R	124	Missense	proximal	-2	no	3.395	3.372	EPSD	COSMIC	3.158	Down-regulation
CMGC_CDK_CDC2_CDK1_ST	O00429	DNM1L	P06493	CDK1	S126	G120C	120	Missense	distal	-6	no	3.395	3.388	EPSD	COSMIC	3.158	Down-regulation
CMGC_CDK_CDC2_CDK1_ST	O00429	DNM1L	P06493	CDK1	S136	K133N	133	Missense	distal	-3	no	3.614	3.635	EPSD	COSMIC	3.158	Up-regulation
CMGC_CDK_CDC2_CDK1_ST	P08670	VIM	P06493	CDK1	T33	S34P	34	Missense	proximal	1	no	0.436	3.621	EPSD	COSMIC	3.158	Gain
CMGC_CDK_CDC2_CDK1_ST	O00512	BCL9	P06493	CDK1	S62	S62F	62	Missense	central	0	yes	3.412	0.000	EPSD	COSMIC	3.158	Loss
CMGC_CDK_CDC2_CDK1_ST	O00512	BCL9	P06493	CDK1	T172	V179L	179	Missense	distal	7	no	3.232	3.239	PhosphoSitePlus	COSMIC	3.158	Up-regulation
CMGC_CDK_CDC2_CDK1_ST	O00512	BCL9	P06493	CDK1	S441	D437H	437	Missense	distal	-4	no	3.178	3.166	EPSD	COSMIC	3.158	Down-regulation
CMGC_CDK_CDC2_CDK1_ST	O00512	BCL9	P06493	CDK1	S687	E683Q	683	Missense	distal	-4	no	3.240	3.251	EPSD	COSMIC	3.158	Up-regulation
CMGC_CDK_CDC2_CDK1_ST	O00512	BCL9	P06493	CDK1	S687	S689F	689	Missense	proximal	2	no	3.240	3.262	EPSD	COSMIC	3.158	Up-regulation
CMGC_CDK_CDC2_CDK1_ST	Q9H410	DSN1	P06493	CDK1	S30	H23D	23	Missense	distal	-7	no	3.403	3.404	EPSD	COSMIC	3.158	Up-regulation
CMGC_CDK_CDC2_CDK1_ST	Q9H410	DSN1	P06493	CDK1	S30	S28I	28	Missense	proximal	-2	no	3.403	3.497	EPSD	COSMIC	3.158	Up-regulation
CMGC_CDK_CDC2_CDK1_ST	Q9H410	DSN1	P06493	CDK1	S30	S28G	28	Missense	proximal	-2	no	3.403	3.492	EPSD	COSMIC	3.158	Up-regulation
CMGC_CDK_CDC2_CDK1_ST	Q9H410	DSN1	P06493	CDK1	S58	S57C	57	Missense	proximal	-1	no	3.055	3.172	EPSD	COSMIC;GDSC;CCLE	3.158	Gain
CMGC_CDK_CDC2_CDK1_ST	Q9H410	DSN1	P06493	CDK1	S58	G62R	62	Missense	distal	4	no	3.055	3.180	EPSD	COSMIC	3.158	Gain
CMGC_CDK_CDC2_CDK1_ST	Q9H410	DSN1	P06493	CDK1	S81	S86F	86	Missense	distal	5	no	3.101	3.267	EPSD	COSMIC	3.158	Gain
CMGC_CDK_CDC2_CDK1_ST	O00311	CDC7	P06493	CDK1	S16	Q18K	18	Missense	proximal	2	no	3.390	3.392	EPSD	COSMIC	3.158	Up-regulation
CMGC_CDK_CDC2_CDK1_ST	P29692	EEF1D	P06493	CDK1	S133	P140H	140	Missense	distal	7	no	3.494	3.501	PhosphoSitePlus	COSMIC	3.158	Up-regulation
CMGC_CDK_CDC2_CDK1_ST	O14773	TPP1	P06493	CDK1	T478	G482E	482	Missense	distal	4	no	3.315	3.378	EPSD	COSMIC	3.158	Up-regulation
CMGC_CDK_CDC2_CDK1_ST	Q8IZP0	ABI1	P06493	CDK1	T196	G193R	193	Missense	distal	-3	no	3.597	3.624	EPSD	COSMIC	3.158	Up-regulation
CMGC_CDK_CDC2_CDK1_ST	Q8IZP0	ABI1	P06493	CDK1	T196	G190E	190	Missense	distal	-6	no	3.597	3.583	EPSD	COSMIC	3.158	Down-regulation
CMGC_CDK_CDC2_CDK1_ST	Q8IZP0	ABI1	P06493	CDK1	T196	N195S	195	Missense	proximal	-1	no	3.597	3.506	EPSD	COSMIC	3.158	Down-regulation
CMGC_CDK_CDC2_CDK1_ST	Q8IZP0	ABI1	P06493	CDK1	S225	H224Y	224	Missense	proximal	-1	no	3.230	3.293	EPSD	COSMIC	3.158	Up-regulation
CMGC_CDK_CDC2_CDK1_ST	P16949	STMN1	P06493	CDK1	S25	Q18E	18	Missense	distal	-7	no	3.749	3.711	PhosphoSitePlus;EPSD	COSMIC	3.158	Down-regulation
CMGC_CDK_CDC2_CDK1_ST	P16949	STMN1	P06493	CDK1	S38	D44N	44	Missense	distal	6	no	3.443	3.451	EPSD;PhosphoSitePlus	COSMIC	3.158	Up-regulation
CMGC_CDK_CDC2_CDK1_ST	P16949	STMN1	P06493	CDK1	S38	P36L	36	Missense	proximal	-2	no	3.443	3.617	EPSD;PhosphoSitePlus	COSMIC	3.158	Up-regulation
CMGC_CDK_CDC2_CDK1_ST	P11387	TOP1	P06493	CDK1	S394	D389Y	389	Missense	distal	-5	no	3.284	3.320	PhosphoSitePlus;EPSD	COSMIC	3.158	Up-regulation
CMGC_CDK_CDC2_CDK1_ST	P78344	EIF4G2	P06493	CDK1	T89	R82G	82	Missense	distal	-7	no	3.991	3.868	EPSD	COSMIC	3.158	Down-regulation
CMGC_CDK_CDC2_CDK1_ST	P78344	EIF4G2	P06493	CDK1	S395	R400C	400	Missense	distal	5	no	3.056	3.164	EPSD	COSMIC	3.158	Gain
CMGC_CDK_CDC2_CDK1_ST	P06400	RB1	P06493	CDK1	T356	E352K	352	Missense	distal	-4	no	3.378	3.324	EPSD	COSMIC	3.158	Down-regulation
CMGC_CDK_CDC2_CDK1_ST	P06400	RB1	P06493	CDK1	T356	R358Q	358	Missense	proximal	2	no	3.378	3.374	EPSD	COSMIC;CCLE	3.158	Down-regulation
CMGC_CDK_CDC2_CDK1_ST	P06400	RB1	P06493	CDK1	T356	N361Y	361	Missense	distal	5	no	3.378	3.456	EPSD	COSMIC	3.158	Up-regulation
CMGC_CDK_CDC2_CDK1_ST	P06400	RB1	P06493	CDK1	S612	R611S	611	Missense	proximal	-1	no	3.596	3.533	EPSD	COSMIC	3.158	Down-regulation
CMGC_CDK_CDC2_CDK1_ST	P06400	RB1	P06493	CDK1	S612	S612P	612	Missense	central	0	yes	3.596	0.000	EPSD	COSMIC	3.158	Loss
CMGC_CDK_CDC2_CDK1_ST	P06400	RB1	P06493	CDK1	S612	Y606C	606	Missense	distal	-6	no	3.596	3.595	EPSD	COSMIC	3.158	Down-regulation
CMGC_CDK_CDC2_CDK1_ST	P06400	RB1	P06493	CDK1	S612	M605T	605	Missense	distal	-7	no	3.596	3.684	EPSD	COSMIC	3.158	Up-regulation
CMGC_CDK_CDC2_CDK1_ST	P06400	RB1	P06493	CDK1	S612	L607V	607	Missense	distal	-5	no	3.596	3.569	EPSD	COSMIC	3.158	Down-regulation
CMGC_CDK_CDC2_CDK1_ST	P06400	RB1	P06493	CDK1	S612	L607I	607	Missense	distal	-5	no	3.596	3.582	EPSD	COSMIC	3.158	Down-regulation
CMGC_CDK_CDC2_CDK1_ST	P06400	RB1	P06493	CDK1	S780	P776R	776	Missense	distal	-4	no	3.910	3.895	EPSD	COSMIC	3.158	Down-regulation
CMGC_CDK_CDC2_CDK1_ST	P06400	RB1	P06493	CDK1	S780	H784Y	784	Missense	distal	4	no	3.910	3.864	EPSD	COSMIC	3.158	Down-regulation
CMGC_CDK_CDC2_CDK1_ST	P06400	RB1	P06493	CDK1	S780	P786S	786	Missense	distal	6	no	3.910	3.917	EPSD	COSMIC	3.158	Up-regulation
CMGC_CDK_CDC2_CDK1_ST	P06400	RB1	P06493	CDK1	S780	S773F	773	Missense	distal	-7	no	3.910	3.764	EPSD	COSMIC	3.158	Down-regulation
CMGC_CDK_CDC2_CDK1_ST	P06400	RB1	P06493	CDK1	S807	G802R	802	Missense	distal	-5	no	3.756	3.688	EPSD;PhosphoSitePlus	COSMIC	3.158	Down-regulation
CMGC_CDK_CDC2_CDK1_ST	P06400	RB1	P06493	CDK1	S807	K814T	814	Missense	distal	7	no	3.756	3.750	EPSD;PhosphoSitePlus	COSMIC	3.158	Down-regulation
CMGC_CDK_CDC2_CDK1_ST	P06400	RB1	P06493	CDK1	S807	G801A	801	Missense	distal	-6	no	3.756	3.732	EPSD;PhosphoSitePlus	COSMIC	3.158	Down-regulation
CMGC_CDK_CDC2_CDK1_ST	P06400	RB1	P06493	CDK1	S811	G818S	818	Missense	distal	7	no	3.368	3.341	EPSD;PhosphoSitePlus	COSMIC	3.158	Down-regulation
CMGC_CDK_CDC2_CDK1_ST	P06400	RB1	P06493	CDK1	S811	G818C	818	Missense	distal	7	no	3.368	3.355	EPSD;PhosphoSitePlus	COSMIC	3.158	Down-regulation
CMGC_CDK_CDC2_CDK1_ST	P06400	RB1	P06493	CDK1	S811	K814T	814	Missense	distal	3	no	3.368	3.281	EPSD;PhosphoSitePlus	COSMIC	3.158	Down-regulation
CMGC_CDK_CDC2_CDK1_ST	Q8WWK9	CKAP2	P06493	CDK1	T579	H575R	575	Missense	distal	-4	no	3.271	3.275	EPSD	COSMIC	3.158	Up-regulation
CMGC_CDK_CDC2_CDK1_ST	Q8WWK9	CKAP2	P06493	CDK1	T579	N581S	581	Missense	proximal	2	no	3.271	3.265	EPSD	COSMIC	3.158	Down-regulation
CMGC_CDK_CDC2_CDK1_ST	Q69YH5	CDCA2	P06493	CDK1	T68	R74L	74	Missense	distal	6	no	3.243	3.173	EPSD	COSMIC	3.158	Down-regulation
CMGC_CDK_CDC2_CDK1_ST	Q69YH5	CDCA2	P06493	CDK1	T68	R74Q	74	Missense	distal	6	no	3.243	3.226	EPSD	COSMIC	3.158	Down-regulation
CMGC_CDK_CDC2_CDK1_ST	Q69YH5	CDCA2	P06493	CDK1	T68	I67T	67	Missense	proximal	-1	no	3.243	3.017	EPSD	COSMIC;GDSC;CCLE	3.158	Loss
CMGC_CDK_CDC2_CDK1_ST	Q69YH5	CDCA2	P06493	CDK1	T68	R74G	74	Missense	distal	6	no	3.243	3.183	EPSD	COSMIC	3.158	Down-regulation
CMGC_CDK_CDC2_CDK1_ST	Q69YH5	CDCA2	P06493	CDK1	T68	V62I	62	Missense	distal	-6	no	3.243	3.246	EPSD	COSMIC	3.158	Up-regulation
CMGC_CDK_CDC2_CDK1_ST	Q69YH5	CDCA2	P06493	CDK1	S98	R96Q	96	Missense	proximal	-2	no	3.244	3.190	EPSD	COSMIC	3.158	Down-regulation
CMGC_CDK_CDC2_CDK1_ST	Q69YH5	CDCA2	P06493	CDK1	S98	P99S	99	Missense	proximal	1	no	3.244	0.059	EPSD	COSMIC	3.158	Loss
CMGC_CDK_CDC2_CDK1_ST	Q69YH5	CDCA2	P06493	CDK1	S98	G94R	94	Missense	distal	-4	no	3.244	3.316	EPSD	COSMIC	3.158	Up-regulation
CMGC_CDK_CDC2_CDK1_ST	Q69YH5	CDCA2	P06493	CDK1	T412	R415H	415	Missense	distal	3	no	3.839	3.747	PhosphoSitePlus	COSMIC	3.158	Down-regulation
CMGC_CDK_CDC2_CDK1_ST	Q69YH5	CDCA2	P06493	CDK1	S437	P440S	440	Missense	distal	3	no	3.507	3.557	EPSD	COSMIC	3.158	Up-regulation
CMGC_CDK_CDC2_CDK1_ST	Q69YH5	CDCA2	P06493	CDK1	S591	E595K	595	Missense	distal	4	no	3.716	3.747	EPSD	COSMIC	3.158	Up-regulation
CMGC_CDK_CDC2_CDK1_ST	Q69YH5	CDCA2	P06493	CDK1	S591	S585F	585	Missense	distal	-6	no	3.716	3.740	EPSD	COSMIC	3.158	Up-regulation
CMGC_CDK_CDC2_CDK1_ST	Q69YH5	CDCA2	P06493	CDK1	S591	P594S	594	Missense	distal	3	no	3.716	3.766	EPSD	COSMIC	3.158	Up-regulation
CMGC_CDK_CDC2_CDK1_ST	Q69YH5	CDCA2	P06493	CDK1	T628	V626M	626	Missense	proximal	-2	no	3.379	3.351	EPSD	COSMIC;GDSC;CCLE	3.158	Down-regulation
CMGC_CDK_CDC2_CDK1_ST	P04179	SOD2	P06493	CDK1	S106	L105R	105	Missense	proximal	-1	no	3.273	3.134	PhosphoSitePlus	COSMIC	3.158	Loss
CMGC_CDK_CDC2_CDK1_ST	P04179	SOD2	P06493	CDK1	S106	G109C	109	Missense	distal	3	no	3.273	3.347	PhosphoSitePlus	COSMIC	3.158	Up-regulation
CMGC_CDK_CDC2_CDK1_ST	O95251	KAT7	P06493	CDK1	S506	G505S	505	Missense	proximal	-1	no	4.232	4.011	EPSD	COSMIC;CCLE	3.158	Down-regulation
CMGC_CDK_CDC2_CDK1_ST	O95251	KAT7	P06493	CDK1	S506	S506F	506	Missense	central	0	yes	4.232	0.000	EPSD	COSMIC	3.158	Loss
CMGC_CDK_CDC2_CDK1_ST	O95251	KAT7	P06493	CDK1	S506	R509H	509	Missense	distal	3	no	4.232	4.139	EPSD	COSMIC	3.158	Down-regulation
CMGC_CDK_CDC2_CDK1_ST	O95251	KAT7	P06493	CDK1	S506	E501K	501	Missense	distal	-5	no	4.232	4.262	EPSD	COSMIC	3.158	Up-regulation
CMGC_CDK_CDC2_CDK1_ST	O95251	KAT7	P06493	CDK1	T606	S601N	601	Missense	distal	-5	no	3.129	3.177	EPSD	COSMIC	3.158	Gain
CMGC_CDK_CDC2_CDK1_ST	Q8TAP9	MPLKIP	P06493	CDK1	S104	Q99H	99	Missense	distal	-5	no	3.568	3.596	PhosphoSitePlus;EPSD	COSMIC	3.158	Up-regulation
CMGC_CDK_CDC2_CDK1_ST	Q96JH7	VCPIP1	P06493	CDK1	S998	L1003Q	1003	Missense	distal	5	no	3.280	3.081	EPSD	COSMIC	3.158	Loss
CMGC_CDK_CDC2_CDK1_ST	Q9H4X1	RGCC	P06493	CDK1	S44	R49H	49	Missense	distal	5	no	3.126	3.191	EPSD	COSMIC	3.158	Gain
CMGC_CDK_CDC2_CDK1_ST	Q9H4X1	RGCC	P06493	CDK1	S44	A43V	43	Missense	proximal	-1	no	3.126	3.326	EPSD	COSMIC	3.158	Gain
CMGC_CDK_CDC2_CDK1_ST	Q9H4X1	RGCC	P06493	CDK1	S97	S97Y	97	Missense	central	0	yes	3.176	0.000	EPSD	COSMIC	3.158	Loss
CMGC_CDK_CDC2_CDK1_ST	Q9H4X1	RGCC	P06493	CDK1	T111	A108T	108	Missense	distal	-3	no	3.896	3.858	PhosphoSitePlus	COSMIC;GDSC;CCLE	3.158	Down-regulation
CMGC_CDK_CDC2_CDK1_ST	Q6PGQ7	BORA	P06493	CDK1	S268	S270L	270	Missense	proximal	2	no	3.196	3.219	EPSD	COSMIC	3.158	Up-regulation
CMGC_CDK_CDC2_CDK1_ST	Q6PGQ7	BORA	P06493	CDK1	S268	S270T	270	Missense	proximal	2	no	3.196	3.197	EPSD	COSMIC	3.158	Up-regulation
CMGC_CDK_CDC2_CDK1_ST	Q6PGQ7	BORA	P06493	CDK1	S274	S270L	270	Missense	distal	-4	no	3.375	3.180	EPSD	COSMIC	3.158	Down-regulation
CMGC_CDK_CDC2_CDK1_ST	Q6PGQ7	BORA	P06493	CDK1	S274	S270T	270	Missense	distal	-4	no	3.375	3.383	EPSD	COSMIC	3.158	Up-regulation
CMGC_CDK_CDC2_CDK1_ST	Q6PGQ7	BORA	P06493	CDK1	S274	T276A	276	Missense	proximal	2	no	3.375	3.368	EPSD	COSMIC	3.158	Down-regulation
CMGC_CDK_CDC2_CDK1_ST	Q96EB6	SIRT1	P06493	CDK1	S14	S14P	14	Missense	central	0	yes	3.510	0.000	EPSD	COSMIC	3.158	Loss
CMGC_CDK_CDC2_CDK1_ST	Q96EB6	SIRT1	P06493	CDK1	S540	E542Q	542	Missense	proximal	2	no	3.799	3.792	EPSD;PhosphoSitePlus	COSMIC	3.158	Down-regulation
CMGC_CDK_CDC2_CDK1_ST	Q96EB6	SIRT1	P06493	CDK1	S540	E536V	536	Missense	distal	-4	no	3.799	3.737	EPSD;PhosphoSitePlus	COSMIC	3.158	Down-regulation
CMGC_CDK_CDC2_CDK1_ST	Q96EB6	SIRT1	P06493	CDK1	S682	E687K	687	Missense	distal	5	no	3.276	3.228	EPSD	COSMIC;GDSC;CCLE	3.158	Down-regulation
CMGC_CDK_CDC2_CDK1_ST	Q9UJX2	CDC23	P06493	CDK1	T562	P563L	563	Missense	proximal	1	no	3.187	-0.500	PhosphoSitePlus;EPSD	COSMIC	3.158	Loss
CMGC_CDK_CDC2_CDK1_ST	Q13535	ATR	P06493	CDK1	S428	R433S	433	Missense	distal	5	no	3.175	3.185	PhosphoSitePlus	COSMIC	3.158	Up-regulation
CMGC_CDK_CDC2_CDK1_ST	Q13535	ATR	P06493	CDK1	S1693	R1696G	1696	Missense	distal	3	no	3.202	3.009	EPSD	COSMIC;GDSC;CCLE	3.158	Loss
CMGC_CDK_CDC2_CDK1_ST	Q13535	ATR	P06493	CDK1	S1693	V1692I	1692	Missense	proximal	-1	no	3.202	3.255	EPSD	COSMIC	3.158	Up-regulation
CMGC_CDK_CDC2_CDK1_ST	Q13535	ATR	P06493	CDK1	T1989	M1996T	1996	Missense	distal	7	no	3.220	3.212	EPSD	COSMIC;GDSC	3.158	Down-regulation
CMGC_CDK_CDC2_CDK1_ST	Q13535	ATR	P06493	CDK1	T1989	P1991S	1991	Missense	proximal	2	no	3.220	3.218	EPSD	COSMIC;GDSC;CCLE	3.158	Down-regulation
CMGC_CDK_CDC2_CDK1_ST	Q13535	ATR	P06493	CDK1	T1989	E1988K	1988	Missense	proximal	-1	no	3.220	3.258	EPSD	COSMIC	3.158	Up-regulation
CMGC_CDK_CDC2_CDK1_ST	Q13535	ATR	P06493	CDK1	T1989	T1989P	1989	Missense	central	0	yes	3.220	0.000	EPSD	COSMIC	3.158	Loss
CMGC_CDK_CDC2_CDK1_ST	Q13535	ATR	P06493	CDK1	T1989	P1985L	1985	Missense	distal	-4	no	3.220	3.076	EPSD	COSMIC	3.158	Loss
CMGC_CDK_CDC2_CDK1_ST	Q13535	ATR	P06493	CDK1	T1989	L1982I	1982	Missense	distal	-7	no	3.220	3.268	EPSD	COSMIC	3.158	Up-regulation
CMGC_CDK_CDC2_CDK1_ST	Q13535	ATR	P06493	CDK1	T1989	E1986K	1986	Missense	distal	-3	no	3.220	3.208	EPSD	COSMIC	3.158	Down-regulation
CMGC_CDK_CDC2_CDK1_ST	Q9ULW0	TPX2	P06493	CDK1	S186	A180T	180	Missense	distal	-6	no	3.208	3.209	EPSD	COSMIC	3.158	Up-regulation
CMGC_CDK_CDC2_CDK1_ST	Q9ULW0	TPX2	P06493	CDK1	S293	P294S	294	Missense	proximal	1	no	3.213	0.029	EPSD	COSMIC	3.158	Loss
CMGC_CDK_CDC2_CDK1_ST	Q9ULW0	TPX2	P06493	CDK1	S293	V297A	297	Missense	distal	4	no	3.213	3.349	EPSD	COSMIC;GDSC;CCLE	3.158	Up-regulation
CMGC_CDK_CDC2_CDK1_ST	Q9ULW0	TPX2	P06493	CDK1	S293	R296Q	296	Missense	distal	3	no	3.213	3.165	EPSD	COSMIC	3.158	Down-regulation
CMGC_CDK_CDC2_CDK1_ST	Q9ULW0	TPX2	P06493	CDK1	S486	V483I	483	Missense	distal	-3	no	3.350	3.329	EPSD	COSMIC	3.158	Down-regulation
CMGC_CDK_CDC2_CDK1_ST	Q9ULW0	TPX2	P06493	CDK1	S486	V483A	483	Missense	distal	-3	no	3.350	3.412	EPSD	COSMIC	3.158	Up-regulation
CMGC_CDK_CDC2_CDK1_ST	Q9ULW0	TPX2	P06493	CDK1	S738	T743A	743	Missense	distal	5	no	3.244	3.180	EPSD;PhosphoSitePlus	COSMIC	3.158	Down-regulation
CMGC_CDK_CDC2_CDK1_ST	P38398	BRCA1	P06493	CDK1	T528	G535R	535	Missense	distal	7	no	3.308	3.289	EPSD	COSMIC	3.158	Down-regulation
CMGC_CDK_CDC2_CDK1_ST	P38398	BRCA1	P06493	CDK1	T528	I532F	532	Missense	distal	4	no	3.308	3.307	EPSD	COSMIC	3.158	Down-regulation
CMGC_CDK_CDC2_CDK1_ST	P38398	BRCA1	P06493	CDK1	T967	E962K	962	Missense	distal	-5	no	3.517	3.548	EPSD	COSMIC;GDSC;CCLE	3.158	Up-regulation
CMGC_CDK_CDC2_CDK1_ST	P38398	BRCA1	P06493	CDK1	T967	T967I	967	Missense	central	0	yes	3.517	0.000	EPSD	COSMIC	3.158	Loss
CMGC_CDK_CDC2_CDK1_ST	P38398	BRCA1	P06493	CDK1	T967	N969I	969	Missense	proximal	2	no	3.517	3.533	EPSD	COSMIC	3.158	Up-regulation
CMGC_CDK_CDC2_CDK1_ST	P38398	BRCA1	P06493	CDK1	S1009	M1008I	1008	Missense	proximal	-1	no	3.117	3.227	EPSD	COSMIC;GDSC	3.158	Gain
CMGC_CDK_CDC2_CDK1_ST	P38398	BRCA1	P06493	CDK1	S1009	M1014I	1014	Missense	distal	5	no	3.117	3.212	EPSD	COSMIC;GDSC;CCLE	3.158	Gain
CMGC_CDK_CDC2_CDK1_ST	P38398	BRCA1	P06493	CDK1	S1211	S1212P	1212	Missense	proximal	1	no	0.462	3.647	EPSD	COSMIC	3.158	Gain
CMGC_CDK_CDC2_CDK1_ST	P38398	BRCA1	P06493	CDK1	S1496	S1497P	1497	Missense	proximal	1	no	0.136	3.320	EPSD	COSMIC	3.158	Gain
CMGC_CDK_CDC2_CDK1_ST	P38398	BRCA1	P06493	CDK1	S1497	P1491L	1491	Missense	distal	-6	no	3.153	3.180	EPSD;PhosphoSitePlus	COSMIC	3.158	Gain
CMGC_CDK_CDC2_CDK1_ST	P38398	BRCA1	P06493	CDK1	S1497	P1502L	1502	Missense	distal	5	no	3.153	3.338	EPSD;PhosphoSitePlus	COSMIC	3.158	Gain
CMGC_CDK_CDC2_CDK1_ST	P38398	BRCA1	P06493	CDK1	S1497	S1499F	1499	Missense	proximal	2	no	3.153	3.175	EPSD;PhosphoSitePlus	COSMIC	3.158	Gain
CMGC_CDK_CDC2_CDK1_ST	P38398	BRCA1	P06493	CDK1	S1497	E1490Q	1490	Missense	distal	-7	no	3.153	3.190	EPSD;PhosphoSitePlus	COSMIC	3.158	Gain
CMGC_CDK_CDC2_CDK1_ST	P38398	BRCA1	P06493	CDK1	S1497	V1493E	1493	Missense	distal	-4	no	3.153	3.215	EPSD;PhosphoSitePlus	COSMIC	3.158	Gain
CMGC_CDK_CDC2_CDK1_ST	P38398	BRCA1	P06493	CDK1	S1613	S1613G	1613	Missense	central	0	yes	3.222	0.000	EPSD	COSMIC	3.158	Loss
CMGC_CDK_CDC2_CDK1_ST	P38398	BRCA1	P06493	CDK1	S1613	T1619S	1619	Missense	distal	6	no	3.222	3.220	EPSD	COSMIC	3.158	Down-regulation
CMGC_CDK_CDC2_CDK1_ST	P38398	BRCA1	P06493	CDK1	S1613	A1608T	1608	Missense	distal	-5	no	3.222	3.244	EPSD	COSMIC	3.158	Up-regulation
CMGC_CDK_CDC2_CDK1_ST	P38398	BRCA1	P06493	CDK1	S1613	Q1612H	1612	Missense	proximal	-1	no	3.222	3.257	EPSD	COSMIC	3.158	Up-regulation
CMGC_CDK_CDC2_CDK1_ST	P38398	BRCA1	P06493	CDK1	S1613	A1615V	1615	Missense	proximal	2	no	3.222	3.245	EPSD	COSMIC	3.158	Up-regulation
CMGC_CDK_CDC2_CDK1_ST	P38398	BRCA1	P06493	CDK1	S1613	V1607M	1607	Missense	distal	-6	no	3.222	3.213	EPSD	COSMIC	3.158	Down-regulation
CMGC_CDK_CDC2_CDK1_ST	P38398	BRCA1	P06493	CDK1	S1613	V1607E	1607	Missense	distal	-6	no	3.222	3.213	EPSD	COSMIC	3.158	Down-regulation
CMGC_CDK_CDC2_CDK1_ST	O95835	LATS1	P06493	CDK1	S204	Y200S	200	Missense	distal	-4	no	3.098	3.197	EPSD	COSMIC	3.158	Gain
CMGC_CDK_CDC2_CDK1_ST	O95835	LATS1	P06493	CDK1	S204	S202F	202	Missense	proximal	-2	no	3.098	3.165	EPSD	COSMIC	3.158	Gain
CMGC_CDK_CDC2_CDK1_ST	O95835	LATS1	P06493	CDK1	T255	P250L	250	Missense	distal	-5	no	3.118	3.239	EPSD	COSMIC	3.158	Gain
CMGC_CDK_CDC2_CDK1_ST	O95835	LATS1	P06493	CDK1	S289	R287Q	287	Missense	proximal	-2	no	3.292	3.238	EPSD	COSMIC	3.158	Down-regulation
CMGC_CDK_CDC2_CDK1_ST	O95835	LATS1	P06493	CDK1	S289	V284I	284	Missense	distal	-5	no	3.292	3.305	EPSD	COSMIC;CCLE	3.158	Up-regulation
CMGC_CDK_CDC2_CDK1_ST	O95835	LATS1	P06493	CDK1	S289	S289C	289	Missense	central	0	yes	3.292	0.000	EPSD	COSMIC	3.158	Loss
CMGC_CDK_CDC2_CDK1_ST	O95835	LATS1	P06493	CDK1	S289	P292S	292	Missense	distal	3	no	3.292	3.342	EPSD	COSMIC	3.158	Up-regulation
CMGC_CDK_CDC2_CDK1_ST	O95835	LATS1	P06493	CDK1	S289	P293S	293	Missense	distal	4	no	3.292	3.289	EPSD	COSMIC	3.158	Down-regulation
CMGC_CDK_CDC2_CDK1_ST	O95835	LATS1	P06493	CDK1	S635	F639L	639	Missense	distal	4	no	3.266	3.243	EPSD	COSMIC	3.158	Down-regulation
CMGC_CDK_CDC2_CDK1_ST	O95835	LATS1	P06493	CDK1	S635	S629P	629	Missense	distal	-6	no	3.266	3.267	EPSD	COSMIC	3.158	Up-regulation
CMGC_CDK_CDC2_CDK1_ST	O95835	LATS1	P06493	CDK1	S635	Q632E	632	Missense	distal	-3	no	3.266	3.243	EPSD	COSMIC	3.158	Down-regulation
CMGC_CDK_CDC2_CDK1_ST	P29590	PML	P06493	CDK1	T196	T198M	198	Missense	proximal	2	no	3.328	3.336	EPSD	COSMIC	3.158	Up-regulation
CMGC_CDK_CDC2_CDK1_ST	P29590	PML	P06493	CDK1	T196	N193S	193	Missense	distal	-3	no	3.328	3.345	EPSD	COSMIC	3.158	Up-regulation
CMGC_CDK_CDC2_CDK1_ST	Q2M2I8	AAK1	P06493	CDK1	T620	P625S	625	Missense	distal	5	no	3.179	3.151	EPSD	COSMIC	3.158	Loss
CMGC_CDK_CDC2_CDK1_ST	Q2M2I8	AAK1	P06493	CDK1	T620	P622L	622	Missense	proximal	2	no	3.179	3.200	EPSD	COSMIC	3.158	Up-regulation
CMGC_CDK_CDC2_CDK1_ST	P49916	LIG3	P06493	CDK1	S242	P243S	243	Missense	proximal	1	no	3.449	0.264	EPSD	COSMIC	3.158	Loss
CMGC_CDK_CDC2_CDK1_ST	P49916	LIG3	P06493	CDK1	S242	G237V	237	Missense	distal	-5	no	3.449	3.440	EPSD	COSMIC	3.158	Down-regulation
CMGC_CDK_CDC2_CDK1_ST	Q14203	DCTN1	P06493	CDK1	S10	R11P	11	Missense	proximal	1	no	-0.359	3.250	EPSD	COSMIC	3.158	Gain
CMGC_CDK_CDC2_CDK1_ST	Q14203	DCTN1	P06493	CDK1	S105	D110N	110	Missense	distal	5	no	3.163	3.115	EPSD	COSMIC	3.158	Loss
CMGC_CDK_CDC2_CDK1_ST	Q14203	DCTN1	P06493	CDK1	S105	E98K	98	Missense	distal	-7	no	3.163	3.118	EPSD	COSMIC	3.158	Loss
CMGC_CDK_CDC2_CDK1_ST	Q14203	DCTN1	P06493	CDK1	S105	S112R	112	Missense	distal	7	no	3.163	3.171	EPSD	COSMIC	3.158	Up-regulation
CMGC_CDK_CDC2_CDK1_ST	Q14203	DCTN1	P06493	CDK1	S105	T108I	108	Missense	distal	3	no	3.163	3.100	EPSD	COSMIC	3.158	Loss
CMGC_CDK_CDC2_CDK1_ST	Q14203	DCTN1	P06493	CDK1	S203	V200F	200	Missense	distal	-3	no	3.392	3.384	EPSD	COSMIC	3.158	Down-regulation
CMGC_CDK_CDC2_CDK1_ST	Q14203	DCTN1	P06493	CDK1	S203	V207G	207	Missense	distal	4	no	3.392	3.360	EPSD	COSMIC	3.158	Down-regulation
CMGC_CDK_CDC2_CDK1_ST	Q14203	DCTN1	P06493	CDK1	S203	V207F	207	Missense	distal	4	no	3.392	3.371	EPSD	COSMIC	3.158	Down-regulation
CMGC_CDK_CDC2_CDK1_ST	Q14203	DCTN1	P06493	CDK1	S212	V207G	207	Missense	distal	-5	no	3.207	3.216	PhosphoSitePlus	COSMIC	3.158	Up-regulation
CMGC_CDK_CDC2_CDK1_ST	Q14203	DCTN1	P06493	CDK1	S212	V207F	207	Missense	distal	-5	no	3.207	3.200	PhosphoSitePlus	COSMIC	3.158	Down-regulation
CMGC_CDK_CDC2_CDK1_ST	Q14203	DCTN1	P06493	CDK1	S212	P213L	213	Missense	proximal	1	no	3.207	-0.479	PhosphoSitePlus	COSMIC	3.158	Loss
CMGC_CDK_CDC2_CDK1_ST	Q14203	DCTN1	P06493	CDK1	S1180	L1185F	1185	Missense	distal	5	no	3.167	3.120	EPSD	COSMIC	3.158	Loss
CMGC_CDK_CDC2_CDK1_ST	Q14203	DCTN1	P06493	CDK1	S1180	S1175I	1175	Missense	distal	-5	no	3.167	3.296	EPSD	COSMIC	3.158	Up-regulation
CMGC_CDK_CDC2_CDK1_ST	Q14203	DCTN1	P06493	CDK1	S1180	P1181L	1181	Missense	proximal	1	no	3.167	-0.520	EPSD	COSMIC	3.158	Loss
CMGC_CDK_CDC2_CDK1_ST	P35251	RFC1	P06493	CDK1	T161	D167Y	167	Missense	distal	6	no	3.642	3.627	EPSD	COSMIC	3.158	Down-regulation
CMGC_CDK_CDC2_CDK1_ST	P35251	RFC1	P06493	CDK1	T161	P157T	157	Missense	distal	-4	no	3.642	3.701	EPSD	COSMIC	3.158	Up-regulation
CMGC_CDK_CDC2_CDK1_ST	O95239	KIF4A	P06493	CDK1	S1013	P1014S	1014	Missense	proximal	1	no	3.656	0.472	EPSD	COSMIC	3.158	Loss
CMGC_CDK_CDC2_CDK1_ST	O95239	KIF4A	P06493	CDK1	S1013	L1006R	1006	Missense	distal	-7	no	3.656	3.821	EPSD	COSMIC;CCLE	3.158	Up-regulation
CMGC_CDK_CDC2_CDK1_ST	O95239	KIF4A	P06493	CDK1	T1181	S1186F	1186	Missense	distal	5	no	3.088	3.254	EPSD	COSMIC;GDSC;CCLE	3.158	Gain
CMGC_CDK_CDC2_CDK1_ST	P36956	SREBF1	P06493	CDK1	T105	P99S	99	Missense	distal	-6	no	3.336	3.335	EPSD	COSMIC	3.158	Down-regulation
CMGC_CDK_CDC2_CDK1_ST	P36956	SREBF1	P06493	CDK1	T105	S112A	112	Missense	distal	7	no	3.336	3.326	EPSD	COSMIC	3.158	Down-regulation
CMGC_CDK_CDC2_CDK1_ST	P36956	SREBF1	P06493	CDK1	T105	P111L	111	Missense	distal	6	no	3.336	3.280	EPSD	COSMIC	3.158	Down-regulation
CMGC_CDK_CDC2_CDK1_ST	P36956	SREBF1	P06493	CDK1	T105	Y110C	110	Missense	distal	5	no	3.336	3.316	EPSD	COSMIC	3.158	Down-regulation
CMGC_CDK_CDC2_CDK1_ST	P36956	SREBF1	P06493	CDK1	T105	P106H	106	Missense	proximal	1	no	3.336	0.652	EPSD	COSMIC	3.158	Loss
CMGC_CDK_CDC2_CDK1_ST	P36956	SREBF1	P06493	CDK1	S439	L443F	443	Missense	distal	4	no	3.310	3.333	PhosphoSitePlus	COSMIC	3.158	Up-regulation
CMGC_CDK_CDC2_CDK1_ST	P36956	SREBF1	P06493	CDK1	S439	P440H	440	Missense	proximal	1	no	3.310	0.626	PhosphoSitePlus	COSMIC	3.158	Loss
CMGC_CDK_CDC2_CDK1_ST	P36956	SREBF1	P06493	CDK1	S1049	T1051I	1051	Missense	proximal	2	no	3.612	3.633	EPSD	COSMIC	3.158	Up-regulation
CMGC_CDK_CDC2_CDK1_ST	P36956	SREBF1	P06493	CDK1	S1049	A1046V	1046	Missense	distal	-3	no	3.612	3.550	EPSD	COSMIC	3.158	Down-regulation
CMGC_CDK_CDC2_CDK1_ST	P36956	SREBF1	P06493	CDK1	S1049	G1047W	1047	Missense	proximal	-2	no	3.612	3.561	EPSD	COSMIC	3.158	Down-regulation
CMGC_CDK_CDC2_CDK1_ST	P05067	APP	P06493	CDK1	T743	V742L	742	Missense	proximal	-1	no	3.318	3.374	PhosphoSitePlus	COSMIC	3.158	Up-regulation
CMGC_CDK_CDC2_CDK1_ST	P05067	APP	P06493	CDK1	T743	E745K	745	Missense	proximal	2	no	3.318	3.314	PhosphoSitePlus	COSMIC	3.158	Down-regulation
CMGC_CDK_CDC2_CDK1_ST	P17706	PTPN2	P06493	CDK1	S52	Y54C	54	Missense	proximal	2	no	3.333	3.331	EPSD	COSMIC	3.158	Down-regulation
CMGC_CDK_CDC2_CDK1_ST	P17706	PTPN2	P06493	CDK1	S52	R45Q	45	Missense	distal	-7	no	3.333	3.339	EPSD	COSMIC	3.158	Up-regulation
CMGC_CDK_CDC2_CDK1_ST	P17706	PTPN2	P06493	CDK1	S52	R58H	58	Missense	distal	6	no	3.333	3.314	EPSD	COSMIC	3.158	Down-regulation
CMGC_CDK_CDC2_CDK1_ST	P17706	PTPN2	P06493	CDK1	S52	R49K	49	Missense	distal	-3	no	3.333	3.322	EPSD	COSMIC	3.158	Down-regulation
CMGC_CDK_CDC2_CDK1_ST	P17706	PTPN2	P06493	CDK1	S298	D302V	302	Missense	distal	4	no	3.171	3.139	EPSD	COSMIC	3.158	Loss
CMGC_CDK_CDC2_CDK1_ST	P17706	PTPN2	P06493	CDK1	S298	P299L	299	Missense	proximal	1	no	3.171	-0.516	EPSD	COSMIC	3.158	Loss
CMGC_CDK_CDC2_CDK1_ST	P17706	PTPN2	P06493	CDK1	S298	D302G	302	Missense	distal	4	no	3.171	3.108	EPSD	COSMIC	3.158	Loss
CMGC_CDK_CDC2_CDK1_ST	P17706	PTPN2	P06493	CDK1	S304	D302V	302	Missense	proximal	-2	no	3.397	3.424	PhosphoSitePlus	COSMIC	3.158	Up-regulation
CMGC_CDK_CDC2_CDK1_ST	P17706	PTPN2	P06493	CDK1	S304	M309R	309	Missense	distal	5	no	3.397	3.318	PhosphoSitePlus	COSMIC	3.158	Down-regulation
CMGC_CDK_CDC2_CDK1_ST	P17706	PTPN2	P06493	CDK1	S304	P299L	299	Missense	distal	-5	no	3.397	3.518	PhosphoSitePlus	COSMIC	3.158	Up-regulation
CMGC_CDK_CDC2_CDK1_ST	P17706	PTPN2	P06493	CDK1	S304	D302G	302	Missense	proximal	-2	no	3.397	3.468	PhosphoSitePlus	COSMIC	3.158	Up-regulation
CMGC_CDK_CDC2_CDK1_ST	Q13009	TIAM1	P06493	CDK1	T61	S58F	58	Missense	distal	-3	no	3.365	3.337	EPSD	COSMIC	3.158	Down-regulation
CMGC_CDK_CDC2_CDK1_ST	Q13009	TIAM1	P06493	CDK1	S1018	P1014H	1014	Missense	distal	-4	no	3.433	3.414	EPSD	COSMIC	3.158	Down-regulation
CMGC_CDK_CDC2_CDK1_ST	Q13009	TIAM1	P06493	CDK1	S1018	Q1022E	1022	Missense	distal	4	no	3.433	3.389	EPSD	COSMIC	3.158	Down-regulation
CMGC_CDK_CDC2_CDK1_ST	Q13009	TIAM1	P06493	CDK1	S1018	S1024Y	1024	Missense	distal	6	no	3.433	3.394	EPSD	COSMIC	3.158	Down-regulation
CMGC_CDK_CDC2_CDK1_ST	Q13009	TIAM1	P06493	CDK1	S1018	D1023V	1023	Missense	distal	5	no	3.433	3.495	EPSD	COSMIC	3.158	Up-regulation
CMGC_CDK_CDC2_CDK1_ST	Q13009	TIAM1	P06493	CDK1	S1018	P1014S	1014	Missense	distal	-4	no	3.433	3.484	EPSD	COSMIC;CCLE	3.158	Up-regulation
CMGC_CDK_CDC2_CDK1_ST	Q13009	TIAM1	P06493	CDK1	S1466	K1469R	1469	Missense	distal	3	no	3.213	3.230	PhosphoSitePlus	COSMIC	3.158	Up-regulation
CMGC_CDK_CDC2_CDK1_ST	Q13009	TIAM1	P06493	CDK1	S1466	A1464E	1464	Missense	proximal	-2	no	3.213	3.371	PhosphoSitePlus	COSMIC	3.158	Up-regulation
CMGC_CDK_CDC2_CDK1_ST	Q9Y3Z3	SAMHD1	P06493	CDK1	T25	A30T	30	Missense	distal	5	no	3.616	3.679	EPSD	COSMIC	3.158	Up-regulation
CMGC_CDK_CDC2_CDK1_ST	Q9Y3Z3	SAMHD1	P06493	CDK1	S33	A30T	30	Missense	distal	-3	no	3.315	3.278	EPSD	COSMIC	3.158	Down-regulation
CMGC_CDK_CDC2_CDK1_ST	Q9Y3Z3	SAMHD1	P06493	CDK1	S278	E277K	277	Missense	proximal	-1	no	3.268	3.306	EPSD	COSMIC	3.158	Up-regulation
CMGC_CDK_CDC2_CDK1_ST	Q9Y3Z3	SAMHD1	P06493	CDK1	S278	G274E	274	Missense	distal	-4	no	3.268	3.346	EPSD	COSMIC	3.158	Up-regulation
CMGC_CDK_CDC2_CDK1_ST	O00267	SUPT5H	P06493	CDK1	S686	R681H	681	Missense	distal	-5	no	3.414	3.409	EPSD	COSMIC	3.158	Down-regulation
CMGC_CDK_CDC2_CDK1_ST	O00267	SUPT5H	P06493	CDK1	S738	T739P	739	Missense	proximal	1	no	0.883	3.316	EPSD	COSMIC	3.158	Gain
CMGC_CDK_CDC2_CDK1_ST	O00267	SUPT5H	P06493	CDK1	T791	P785S	785	Missense	distal	-6	no	3.587	3.585	EPSD	COSMIC	3.158	Down-regulation
CMGC_CDK_CDC2_CDK1_ST	O00267	SUPT5H	P06493	CDK1	T791	G788D	788	Missense	distal	-3	no	3.587	3.624	EPSD	COSMIC	3.158	Up-regulation
CMGC_CDK_CDC2_CDK1_ST	O00267	SUPT5H	P06493	CDK1	T791	G788S	788	Missense	distal	-3	no	3.587	3.641	EPSD	COSMIC	3.158	Up-regulation
CMGC_CDK_CDC2_CDK1_ST	O00267	SUPT5H	P06493	CDK1	T791	S789L	789	Missense	proximal	-2	no	3.587	3.634	EPSD	COSMIC;GDSC;CCLE	3.158	Up-regulation
CMGC_CDK_CDC2_CDK1_ST	O00267	SUPT5H	P06493	CDK1	T854	P857S	857	Missense	distal	3	no	3.248	3.298	EPSD	COSMIC	3.158	Up-regulation
CMGC_CDK_CDC2_CDK1_ST	O00267	SUPT5H	P06493	CDK1	T854	P857L	857	Missense	distal	3	no	3.248	3.115	EPSD	COSMIC	3.158	Loss
CMGC_CDK_CDC2_CDK1_ST	O00267	SUPT5H	P06493	CDK1	T854	P848L	848	Missense	distal	-6	no	3.248	3.274	EPSD	COSMIC	3.158	Up-regulation
CMGC_CDK_CDC2_CDK1_ST	O00267	SUPT5H	P06493	CDK1	T967	T967P	967	Missense	central	0	yes	3.199	0.000	EPSD	COSMIC	3.158	Loss
CMGC_CDK_CDC2_CDK1_ST	O00267	SUPT5H	P06493	CDK1	T967	G962V	962	Missense	distal	-5	no	3.199	3.190	EPSD	COSMIC	3.158	Down-regulation
CMGC_CDK_CDC2_CDK1_ST	O00267	SUPT5H	P06493	CDK1	T1034	N1039S	1039	Missense	distal	5	no	3.753	3.712	EPSD	COSMIC	3.158	Down-regulation
CMGC_CDK_CDC2_CDK1_ST	O00267	SUPT5H	P06493	CDK1	T1034	K1040R	1040	Missense	distal	6	no	3.753	3.778	EPSD	COSMIC	3.158	Up-regulation
CMGC_CDK_CDC2_CDK1_ST	O00267	SUPT5H	P06493	CDK1	T1034	N1039K	1039	Missense	distal	5	no	3.753	3.745	EPSD	COSMIC	3.158	Down-regulation
CMGC_CDK_CDC2_CDK1_ST	Q9UKX7	NUP50	P06493	CDK1	S221	L224F	224	Missense	distal	3	no	3.181	3.233	PhosphoSitePlus	COSMIC	3.158	Up-regulation
CMGC_CDK_CDC2_CDK1_ST	Q96KB5	PBK	P06493	CDK1	T24	P30L	30	Missense	distal	6	no	3.161	3.104	EPSD	COSMIC	3.158	Loss
CMGC_CDK_CDC2_CDK1_ST	Q96KB5	PBK	P06493	CDK1	T24	K17N	17	Missense	distal	-7	no	3.161	3.213	EPSD	COSMIC;GDSC;CCLE	3.158	Up-regulation
CMGC_CDK_CDC2_CDK1_ST	Q96KB5	PBK	P06493	CDK1	T24	A31T	31	Missense	distal	7	no	3.161	3.174	EPSD	COSMIC	3.158	Up-regulation
CMGC_CDK_CDC2_CDK1_ST	Q96KB5	PBK	P06493	CDK1	T24	S19A	19	Missense	distal	-5	no	3.161	3.137	EPSD	COSMIC	3.158	Loss
CMGC_CDK_CDC2_CDK1_ST	Q96KB5	PBK	P06493	CDK1	S32	P30L	30	Missense	proximal	-2	no	3.079	3.252	EPSD	COSMIC	3.158	Gain
CMGC_CDK_CDC2_CDK1_ST	P10415	BCL2	P06493	CDK1	T74	T74N	74	Missense	central	0	yes	3.764	0.000	EPSD	COSMIC	3.158	Loss
CMGC_CDK_CDC2_CDK1_ST	P10415	BCL2	P06493	CDK1	T74	T69A	69	Missense	distal	-5	no	3.764	3.743	EPSD	COSMIC	3.158	Down-regulation
CMGC_CDK_CDC2_CDK1_ST	P10415	BCL2	P06493	CDK1	T74	A67V	67	Missense	distal	-7	no	3.764	3.612	EPSD	COSMIC	3.158	Down-regulation
CMGC_CDK_CDC2_CDK1_ST	P10415	BCL2	P06493	CDK1	T74	A76T	76	Missense	proximal	2	no	3.764	3.770	EPSD	COSMIC	3.158	Up-regulation
CMGC_CDK_CDC2_CDK1_ST	P10415	BCL2	P06493	CDK1	T74	A77V	77	Missense	distal	3	no	3.764	3.611	EPSD	COSMIC	3.158	Down-regulation
CMGC_CDK_CDC2_CDK1_ST	P10415	BCL2	P06493	CDK1	T74	A76S	76	Missense	proximal	2	no	3.764	3.770	EPSD	COSMIC	3.158	Up-regulation
CMGC_CDK_CDC2_CDK1_ST	P10415	BCL2	P06493	CDK1	T74	T74A	74	Missense	central	0	yes	3.764	0.000	EPSD	COSMIC	3.158	Loss
CMGC_CDK_CDC2_CDK1_ST	P10415	BCL2	P06493	CDK1	T74	A80V	80	Missense	distal	6	no	3.764	3.716	EPSD	COSMIC	3.158	Down-regulation
CMGC_CDK_CDC2_CDK1_ST	P10415	BCL2	P06493	CDK1	T74	T74I	74	Missense	central	0	yes	3.764	0.000	EPSD	COSMIC	3.158	Loss
CMGC_CDK_CDC2_CDK1_ST	P10415	BCL2	P06493	CDK1	T74	T69P	69	Missense	distal	-5	no	3.764	3.788	EPSD	COSMIC;CCLE	3.158	Up-regulation
CMGC_CDK_CDC2_CDK1_ST	O14745	SLC9A3R1	P06493	CDK1	S280	L285M	285	Missense	distal	5	no	3.201	3.057	EPSD;PhosphoSitePlus	COSMIC	3.158	Loss
CMGC_CDK_CDC2_CDK1_ST	O14745	SLC9A3R1	P06493	CDK1	S280	E275V	275	Missense	distal	-5	no	3.201	3.264	EPSD;PhosphoSitePlus	COSMIC	3.158	Up-regulation
CMGC_CDK_CDC2_CDK1_ST	O14745	SLC9A3R1	P06493	CDK1	S280	A277D	277	Missense	distal	-3	no	3.201	3.142	EPSD;PhosphoSitePlus	COSMIC	3.158	Loss
CMGC_CDK_CDC2_CDK1_ST	O14745	SLC9A3R1	P06493	CDK1	S280	E279D	279	Missense	proximal	-1	no	3.201	3.193	EPSD;PhosphoSitePlus	COSMIC	3.158	Down-regulation
CMGC_CDK_CDC2_CDK1_ST	P27824	CANX	P06493	CDK1	S583	I579S	579	Missense	distal	-4	no	3.130	3.273	PhosphoSitePlus	COSMIC;CCLE	3.158	Gain
CMGC_CDK_CDC2_CDK1_ST	P54578	USP14	P06493	CDK1	T235	S230R	230	Missense	distal	-5	no	3.341	3.398	PhosphoSitePlus	COSMIC	3.158	Up-regulation
CMGC_CDK_CDC2_CDK1_ST	P54578	USP14	P06493	CDK1	T235	S230F	230	Missense	distal	-5	no	3.341	3.450	PhosphoSitePlus	COSMIC	3.158	Up-regulation
CMGC_CDK_CDC2_CDK1_ST	P54578	USP14	P06493	CDK1	T235	S241R	241	Missense	distal	6	no	3.341	3.346	PhosphoSitePlus	COSMIC	3.158	Up-regulation
CMGC_CDK_CDC2_CDK1_ST	P54578	USP14	P06493	CDK1	T235	K239N	239	Missense	distal	4	no	3.341	3.336	PhosphoSitePlus	COSMIC	3.158	Down-regulation
CMGC_CDK_CDC2_CDK1_ST	P54578	USP14	P06493	CDK1	T235	P236T	236	Missense	proximal	1	no	3.341	0.907	PhosphoSitePlus	COSMIC	3.158	Loss
CMGC_CDK_CDC2_CDK1_ST	P54578	USP14	P06493	CDK1	S394	Q396K	396	Missense	proximal	2	no	3.421	3.423	EPSD	COSMIC	3.158	Up-regulation
CMGC_CDK_CDC2_CDK1_ST	P54578	USP14	P06493	CDK1	S394	K397R	397	Missense	distal	3	no	3.421	3.438	EPSD	COSMIC	3.158	Up-regulation
CMGC_CDK_CDC2_CDK1_ST	P54578	USP14	P06493	CDK1	S394	D390N	390	Missense	distal	-4	no	3.421	3.406	EPSD	COSMIC	3.158	Down-regulation
CMGC_CDK_CDC2_CDK1_ST	P54578	USP14	P06493	CDK1	T459	I463V	463	Missense	distal	4	no	3.815	3.835	EPSD	COSMIC	3.158	Up-regulation
CMGC_CDK_CDC2_CDK1_ST	P54578	USP14	P06493	CDK1	T459	K454E	454	Missense	distal	-5	no	3.815	3.785	EPSD	COSMIC	3.158	Down-regulation
CMGC_CDK_CDC2_CDK1_ST	P54578	USP14	P06493	CDK1	T459	V458I	458	Missense	proximal	-1	no	3.815	3.868	EPSD	COSMIC	3.158	Up-regulation
CMGC_CDK_CDC2_CDK1_ST	P54578	USP14	P06493	CDK1	T459	P460Q	460	Missense	proximal	1	no	3.815	1.393	EPSD	COSMIC	3.158	Loss
CMGC_CDK_CDC2_CDK1_ST	P23769	GATA2	P06493	CDK1	S73	A75G	75	Missense	proximal	2	no	3.602	3.632	EPSD	COSMIC	3.158	Up-regulation
CMGC_CDK_CDC2_CDK1_ST	P23769	GATA2	P06493	CDK1	S73	V70I	70	Missense	distal	-3	no	3.602	3.582	EPSD	COSMIC	3.158	Down-regulation
CMGC_CDK_CDC2_CDK1_ST	P23769	GATA2	P06493	CDK1	S73	A68E	68	Missense	distal	-5	no	3.602	3.679	EPSD	COSMIC	3.158	Up-regulation
CMGC_CDK_CDC2_CDK1_ST	P23769	GATA2	P06493	CDK1	S73	A68V	68	Missense	distal	-5	no	3.602	3.743	EPSD	COSMIC	3.158	Up-regulation
CMGC_CDK_CDC2_CDK1_ST	P23769	GATA2	P06493	CDK1	S73	S71F	71	Missense	proximal	-2	no	3.602	3.670	EPSD	COSMIC;GDSC;CCLE	3.158	Up-regulation
CMGC_CDK_CDC2_CDK1_ST	P23769	GATA2	P06493	CDK1	S119	S122F	122	Missense	distal	3	no	3.475	3.344	EPSD	COSMIC	3.158	Down-regulation
CMGC_CDK_CDC2_CDK1_ST	P23769	GATA2	P06493	CDK1	S119	S122T	122	Missense	distal	3	no	3.475	3.440	EPSD	COSMIC	3.158	Down-regulation
CMGC_CDK_CDC2_CDK1_ST	P23769	GATA2	P06493	CDK1	S119	P125T	125	Missense	distal	6	no	3.475	3.484	EPSD	COSMIC;CCLE	3.158	Up-regulation
CMGC_CDK_CDC2_CDK1_ST	P23769	GATA2	P06493	CDK1	S119	T117I	117	Missense	proximal	-2	no	3.475	3.608	EPSD	COSMIC	3.158	Up-regulation
CMGC_CDK_CDC2_CDK1_ST	P23769	GATA2	P06493	CDK1	S119	K123N	123	Missense	distal	4	no	3.475	3.470	EPSD	COSMIC;CCLE	3.158	Down-regulation
CMGC_CDK_CDC2_CDK1_ST	P23769	GATA2	P06493	CDK1	T303	P304L	304	Missense	proximal	1	no	3.244	-0.442	EPSD	COSMIC	3.158	Loss
CMGC_CDK_CDC2_CDK1_ST	P23769	GATA2	P06493	CDK1	T303	R307W	307	Missense	distal	4	no	3.244	3.171	EPSD	COSMIC;CCLE	3.158	Down-regulation
CMGC_CDK_CDC2_CDK1_ST	P23769	GATA2	P06493	CDK1	T303	P304H	304	Missense	proximal	1	no	3.244	0.560	EPSD	COSMIC	3.158	Loss
CMGC_CDK_CDC2_CDK1_ST	P23769	GATA2	P06493	CDK1	T303	P304T	304	Missense	proximal	1	no	3.244	0.811	EPSD	COSMIC	3.158	Loss
CMGC_CDK_CDC2_CDK1_ST	P23769	GATA2	P06493	CDK1	T303	R307L	307	Missense	distal	4	no	3.244	3.108	EPSD	COSMIC	3.158	Loss
CMGC_CDK_CDC2_CDK1_ST	P23769	GATA2	P06493	CDK1	T303	N297K	297	Missense	distal	-6	no	3.244	3.247	EPSD	COSMIC	3.158	Up-regulation
CMGC_CDK_CDC2_CDK1_ST	P23769	GATA2	P06493	CDK1	T303	A302S	302	Missense	proximal	-1	no	3.244	3.298	EPSD	COSMIC	3.158	Up-regulation
CMGC_CDK_CDC2_CDK1_ST	P23769	GATA2	P06493	CDK1	T303	T303I	303	Missense	central	0	yes	3.244	0.000	EPSD	COSMIC	3.158	Loss
CMGC_CDK_CDC2_CDK1_ST	P23769	GATA2	P06493	CDK1	T303	N297S	297	Missense	distal	-6	no	3.244	3.236	EPSD	COSMIC	3.158	Down-regulation
CMGC_CDK_CDC2_CDK1_ST	P23769	GATA2	P06493	CDK1	T303	G299E	299	Missense	distal	-4	no	3.244	3.323	EPSD	COSMIC	3.158	Up-regulation
CMGC_CDK_CDC2_CDK1_ST	P23769	GATA2	P06493	CDK1	T303	D309V	309	Missense	distal	6	no	3.244	3.231	EPSD	COSMIC	3.158	Down-regulation
CMGC_CDK_CDC2_CDK1_ST	O14980	XPO1	P06493	CDK1	S384	A377T	377	Missense	distal	-7	no	3.405	3.398	EPSD	COSMIC	3.158	Down-regulation
CMGC_CDK_CDC2_CDK1_ST	O14980	XPO1	P06493	CDK1	S384	E383K	383	Missense	proximal	-1	no	3.405	3.443	EPSD	COSMIC	3.158	Up-regulation
CMGC_CDK_CDC2_CDK1_ST	O14980	XPO1	P06493	CDK1	S391	G396E	396	Missense	distal	5	no	3.438	3.335	PhosphoSitePlus	COSMIC	3.158	Down-regulation
CMGC_CDK_CDC2_CDK1_ST	O14980	XPO1	P06493	CDK1	S391	S395F	395	Missense	distal	4	no	3.438	3.342	PhosphoSitePlus	COSMIC	3.158	Down-regulation
CMGC_CDK_CDC2_CDK1_ST	O14980	XPO1	P06493	CDK1	S391	P392A	392	Missense	proximal	1	no	3.438	2.549	PhosphoSitePlus	COSMIC	3.158	Loss
CMGC_CDK_CDC2_CDK1_ST	O14980	XPO1	P06493	CDK1	S391	Q398E	398	Missense	distal	7	no	3.438	3.448	PhosphoSitePlus	COSMIC	3.158	Up-regulation
CMGC_CDK_CDC2_CDK1_ST	Q13501	SQSTM1	P06493	CDK1	S28	R22W	22	Missense	distal	-6	no	3.304	3.312	EPSD	COSMIC	3.158	Up-regulation
CMGC_CDK_CDC2_CDK1_ST	Q13501	SQSTM1	P06493	CDK1	S28	A33V	33	Missense	distal	5	no	3.304	3.511	EPSD	COSMIC	3.158	Up-regulation
CMGC_CDK_CDC2_CDK1_ST	Q13501	SQSTM1	P06493	CDK1	S28	E34K	34	Missense	distal	6	no	3.304	3.306	EPSD	COSMIC	3.158	Up-regulation
CMGC_CDK_CDC2_CDK1_ST	Q8IX03	WWC1	P06493	CDK1	S358	G365W	365	Missense	distal	7	no	3.522	3.510	EPSD	COSMIC	3.158	Down-regulation
CMGC_CDK_CDC2_CDK1_ST	Q8IX03	WWC1	P06493	CDK1	S358	R360H	360	Missense	proximal	2	no	3.522	3.527	EPSD	COSMIC	3.158	Up-regulation
CMGC_CDK_CDC2_CDK1_ST	Q8IX03	WWC1	P06493	CDK1	T895	P900T	900	Missense	distal	5	no	3.526	3.504	EPSD	COSMIC	3.158	Down-regulation
CMGC_CDK_CDC2_CDK1_ST	Q8IX03	WWC1	P06493	CDK1	T895	P898L	898	Missense	distal	3	no	3.526	3.394	EPSD	COSMIC	3.158	Down-regulation
CMGC_CDK_CDC2_CDK1_ST	Q8IX03	WWC1	P06493	CDK1	T895	P900S	900	Missense	distal	5	no	3.526	3.498	EPSD	COSMIC	3.158	Down-regulation
CMGC_CDK_CDC2_CDK1_ST	Q8IX03	WWC1	P06493	CDK1	T895	P896L	896	Missense	proximal	1	no	3.526	-0.160	EPSD	COSMIC	3.158	Loss
CMGC_CDK_CDC2_CDK1_ST	Q8IX03	WWC1	P06493	CDK1	T912	P913S	913	Missense	proximal	1	no	3.247	0.062	EPSD	COSMIC	3.158	Loss
CMGC_CDK_CDC2_CDK1_ST	Q14244	MAP7	P06493	CDK1	S209	S209Y	209	Missense	central	0	yes	3.353	0.000	PhosphoSitePlus	COSMIC;CCLE	3.158	Loss
CMGC_CDK_CDC2_CDK1_ST	Q14244	MAP7	P06493	CDK1	S209	L206S	206	Missense	distal	-3	no	3.353	3.384	PhosphoSitePlus	COSMIC	3.158	Up-regulation
CMGC_CDK_CDC2_CDK1_ST	Q14244	MAP7	P06493	CDK1	S315	R311C	311	Missense	distal	-4	no	3.416	3.347	EPSD	COSMIC	3.158	Down-regulation
CMGC_CDK_CDC2_CDK1_ST	Q14244	MAP7	P06493	CDK1	S315	S315C	315	Missense	central	0	yes	3.416	0.000	EPSD	COSMIC	3.158	Loss
CMGC_CDK_CDC2_CDK1_ST	Q14244	MAP7	P06493	CDK1	S315	R312M	312	Missense	distal	-3	no	3.416	3.429	EPSD	COSMIC;GDSC	3.158	Up-regulation
CMGC_CDK_CDC2_CDK1_ST	Q14244	MAP7	P06493	CDK1	S315	N318D	318	Missense	distal	3	no	3.416	3.342	EPSD	COSMIC	3.158	Down-regulation
CMGC_CDK_CDC2_CDK1_ST	Q14244	MAP7	P06493	CDK1	S714	E713K	713	Missense	proximal	-1	no	3.464	3.502	EPSD	COSMIC	3.158	Up-regulation
CMGC_CDK_CDC2_CDK1_ST	Q14244	MAP7	P06493	CDK1	S714	P721S	721	Missense	distal	7	no	3.464	3.462	EPSD	COSMIC	3.158	Down-regulation
CMGC_CDK_CDC2_CDK1_ST	Q14244	MAP7	P06493	CDK1	S714	P721L	721	Missense	distal	7	no	3.464	3.492	EPSD	COSMIC	3.158	Up-regulation
CMGC_CDK_CDC2_CDK1_ST	Q14244	MAP7	P06493	CDK1	S714	P715Q	715	Missense	proximal	1	no	3.464	1.041	EPSD	COSMIC	3.158	Loss
CMGC_CDK_CDC2_CDK1_ST	P35611	ADD1	P06493	CDK1	S600	E598G	598	Missense	proximal	-2	no	3.125	3.177	EPSD	COSMIC	3.158	Gain
CMGC_CDK_CDC2_CDK1_ST	P35611	ADD1	P06493	CDK1	S710	G709V	709	Missense	proximal	-1	no	3.286	3.212	EPSD	COSMIC	3.158	Down-regulation
CMGC_CDK_CDC2_CDK1_ST	P35611	ADD1	P06493	CDK1	S710	S710F	710	Missense	central	0	yes	3.286	0.000	EPSD	COSMIC	3.158	Loss
CMGC_CDK_CDC2_CDK1_ST	P35611	ADD1	P06493	CDK1	S710	A703V	703	Missense	distal	-7	no	3.286	3.134	EPSD	COSMIC	3.158	Loss
CMGC_CDK_CDC2_CDK1_ST	P35611	ADD1	P06493	CDK1	S710	G712D	712	Missense	proximal	2	no	3.286	3.273	EPSD	COSMIC	3.158	Down-regulation
CMGC_CDK_CDC2_CDK1_ST	P35611	ADD1	P06493	CDK1	S714	G709V	709	Missense	distal	-5	no	3.399	3.390	EPSD	COSMIC	3.158	Down-regulation
CMGC_CDK_CDC2_CDK1_ST	P35611	ADD1	P06493	CDK1	S714	S710F	710	Missense	distal	-4	no	3.399	3.253	EPSD	COSMIC	3.158	Down-regulation
CMGC_CDK_CDC2_CDK1_ST	P35611	ADD1	P06493	CDK1	S714	G712D	712	Missense	proximal	-2	no	3.399	3.328	EPSD	COSMIC	3.158	Down-regulation
CMGC_CDK_CDC2_CDK1_ST	Q96T23	RSF1	P06493	CDK1	S397	L391Q	391	Missense	distal	-6	no	3.191	3.168	EPSD	COSMIC	3.158	Down-regulation
CMGC_CDK_CDC2_CDK1_ST	Q96T23	RSF1	P06493	CDK1	S397	G401E	401	Missense	distal	4	no	3.191	3.254	EPSD	COSMIC	3.158	Up-regulation
CMGC_CDK_CDC2_CDK1_ST	Q96T23	RSF1	P06493	CDK1	S397	C404R	404	Missense	distal	7	no	3.191	3.185	EPSD	COSMIC	3.158	Down-regulation
CMGC_CDK_CDC2_CDK1_ST	Q96T23	RSF1	P06493	CDK1	S397	G401V	401	Missense	distal	4	no	3.191	3.223	EPSD	COSMIC	3.158	Up-regulation
CMGC_CDK_CDC2_CDK1_ST	Q96T23	RSF1	P06493	CDK1	S397	V399F	399	Missense	proximal	2	no	3.191	3.197	EPSD	COSMIC	3.158	Up-regulation
CMGC_CDK_CDC2_CDK1_ST	Q96T23	RSF1	P06493	CDK1	S570	T573I	573	Missense	distal	3	no	3.340	3.277	EPSD	COSMIC	3.158	Down-regulation
CMGC_CDK_CDC2_CDK1_ST	Q96T23	RSF1	P06493	CDK1	S570	E568K	568	Missense	proximal	-2	no	3.340	3.369	EPSD	COSMIC	3.158	Up-regulation
CMGC_CDK_CDC2_CDK1_ST	Q96T23	RSF1	P06493	CDK1	S570	K572N	572	Missense	proximal	2	no	3.340	3.341	EPSD	COSMIC	3.158	Up-regulation
CMGC_CDK_CDC2_CDK1_ST	Q96T23	RSF1	P06493	CDK1	S570	K569Q	569	Missense	proximal	-1	no	3.340	3.259	EPSD	COSMIC;CCLE	3.158	Down-regulation
CMGC_CDK_CDC2_CDK1_ST	Q96T23	RSF1	P06493	CDK1	S604	E609G	609	Missense	distal	5	no	3.244	3.346	EPSD	COSMIC	3.158	Up-regulation
CMGC_CDK_CDC2_CDK1_ST	Q96T23	RSF1	P06493	CDK1	S604	R602T	602	Missense	proximal	-2	no	3.244	3.138	EPSD	COSMIC	3.158	Loss
CMGC_CDK_CDC2_CDK1_ST	Q96T23	RSF1	P06493	CDK1	S604	D597N	597	Missense	distal	-7	no	3.244	3.245	EPSD	COSMIC	3.158	Up-regulation
CMGC_CDK_CDC2_CDK1_ST	Q96T23	RSF1	P06493	CDK1	S622	S622A	622	Missense	central	0	yes	3.296	0.000	EPSD	COSMIC	3.158	Loss
CMGC_CDK_CDC2_CDK1_ST	Q96T23	RSF1	P06493	CDK1	S629	S622A	622	Missense	distal	-7	no	3.551	3.579	EPSD	COSMIC	3.158	Up-regulation
CMGC_CDK_CDC2_CDK1_ST	Q96T23	RSF1	P06493	CDK1	S629	E624D	624	Missense	distal	-5	no	3.551	3.542	EPSD	COSMIC	3.158	Down-regulation
CMGC_CDK_CDC2_CDK1_ST	Q96T23	RSF1	P06493	CDK1	S778	S782F	782	Missense	distal	4	no	3.163	3.067	EPSD	COSMIC	3.158	Loss
CMGC_CDK_CDC2_CDK1_ST	Q96T23	RSF1	P06493	CDK1	S778	T774A	774	Missense	distal	-4	no	3.163	3.127	EPSD	COSMIC	3.158	Loss
CMGC_CDK_CDC2_CDK1_ST	Q96T23	RSF1	P06493	CDK1	S778	T774N	774	Missense	distal	-4	no	3.163	3.082	EPSD	COSMIC	3.158	Loss
CMGC_CDK_CDC2_CDK1_ST	P24864	CCNE1	P06493	CDK1	T77	P76L	76	Missense	proximal	-1	no	3.122	3.272	EPSD	COSMIC	3.158	Gain
CMGC_CDK_CDC2_CDK1_ST	P24864	CCNE1	P06493	CDK1	S103	V107L	107	Missense	distal	4	no	3.241	3.198	EPSD	COSMIC;CCLE	3.158	Down-regulation
CMGC_CDK_CDC2_CDK1_ST	P24864	CCNE1	P06493	CDK1	S387	A386V	386	Missense	proximal	-1	no	3.066	3.266	EPSD	COSMIC	3.158	Gain
CMGC_CDK_CDC2_CDK1_ST	P24864	CCNE1	P06493	CDK1	T395	L389F	389	Missense	distal	-6	no	3.467	3.463	EPSD	COSMIC	3.158	Down-regulation
CMGC_CDK_CDC2_CDK1_ST	P24864	CCNE1	P06493	CDK1	T395	S391R	391	Missense	distal	-4	no	3.467	3.401	EPSD	COSMIC	3.158	Down-regulation
CMGC_CDK_CDC2_CDK1_ST	P24864	CCNE1	P06493	CDK1	T395	T395P	395	Missense	central	0	yes	3.467	0.000	EPSD	COSMIC	3.158	Loss
CMGC_CDK_CDC2_CDK1_ST	O43521	BCL2L11	P06493	CDK1	S59	P60S	60	Missense	proximal	1	no	3.382	0.197	EPSD	COSMIC	3.158	Loss
CMGC_CDK_CDC2_CDK1_ST	O43521	BCL2L11	P06493	CDK1	S59	P66S	66	Missense	distal	7	no	3.382	3.380	EPSD	COSMIC	3.158	Down-regulation
CMGC_CDK_CDC2_CDK1_ST	O43521	BCL2L11	P06493	CDK1	S59	G58S	58	Missense	proximal	-1	no	3.382	3.161	EPSD	COSMIC	3.158	Down-regulation
CMGC_CDK_CDC2_CDK1_ST	O43521	BCL2L11	P06493	CDK1	S69	A74V	74	Missense	distal	5	no	3.155	3.363	EPSD	COSMIC	3.158	Gain
CMGC_CDK_CDC2_CDK1_ST	O43521	BCL2L11	P06493	CDK1	S69	P72S	72	Missense	distal	3	no	3.155	3.206	EPSD	COSMIC	3.158	Gain
CMGC_CDK_CDC2_CDK1_ST	Q13188	STK3	P06493	CDK1	S79	S79I	79	Missense	central	0	yes	3.487	0.000	EPSD	COSMIC	3.158	Loss
CMGC_CDK_CDC2_CDK1_ST	Q13188	STK3	P06493	CDK1	S79	C77R	77	Missense	proximal	-2	no	3.487	3.537	EPSD	COSMIC	3.158	Up-regulation
CMGC_CDK_CDC2_CDK1_ST	Q13188	STK3	P06493	CDK1	S79	D78G	78	Missense	proximal	-1	no	3.487	3.622	EPSD	COSMIC	3.158	Up-regulation
CMGC_CDK_CDC2_CDK1_ST	Q13188	STK3	P06493	CDK1	S79	I73L	73	Missense	distal	-6	no	3.487	3.492	EPSD	COSMIC	3.158	Up-regulation
CMGC_CDK_CDC2_CDK1_ST	Q13188	STK3	P06493	CDK1	S79	V82I	82	Missense	distal	3	no	3.487	3.489	EPSD	COSMIC	3.158	Up-regulation
CMGC_CDK_CDC2_CDK1_ST	Q13188	STK3	P06493	CDK1	S79	Y81H	81	Missense	proximal	2	no	3.487	3.482	EPSD	COSMIC	3.158	Down-regulation
CMGC_CDK_CDC2_CDK1_ST	Q13188	STK3	P06493	CDK1	S79	S79G	79	Missense	central	0	yes	3.487	0.000	EPSD	COSMIC	3.158	Loss
CMGC_CDK_CDC2_CDK1_ST	Q13188	STK3	P06493	CDK1	S79	S72P	72	Missense	distal	-7	no	3.487	3.446	EPSD	COSMIC	3.158	Down-regulation
CMGC_CDK_CDC2_CDK1_ST	Q13188	STK3	P06493	CDK1	S79	S72F	72	Missense	distal	-7	no	3.487	3.340	EPSD	COSMIC	3.158	Down-regulation
CMGC_CDK_CDC2_CDK1_ST	Q13188	STK3	P06493	CDK1	T184	N179S	179	Missense	distal	-5	no	3.268	3.220	EPSD	COSMIC;CCLE	3.158	Down-regulation
CMGC_CDK_CDC2_CDK1_ST	Q13188	STK3	P06493	CDK1	T184	R178H	178	Missense	distal	-6	no	3.268	3.272	EPSD	COSMIC;GDSC;CCLE	3.158	Up-regulation
CMGC_CDK_CDC2_CDK1_ST	Q13188	STK3	P06493	CDK1	T184	R178C	178	Missense	distal	-6	no	3.268	3.277	EPSD	COSMIC	3.158	Up-regulation
CMGC_CDK_CDC2_CDK1_ST	Q13188	STK3	P06493	CDK1	T184	M188T	188	Missense	distal	4	no	3.268	3.308	EPSD	COSMIC	3.158	Up-regulation
CMGC_CDK_CDC2_CDK1_ST	Q13188	STK3	P06493	CDK1	T184	V181L	181	Missense	distal	-3	no	3.268	3.255	EPSD	COSMIC	3.158	Down-regulation
CMGC_CDK_CDC2_CDK1_ST	Q96C36	PYCR2	P06493	CDK1	S233	H240N	240	Missense	distal	7	no	3.541	3.539	EPSD	COSMIC	3.158	Down-regulation
CMGC_CDK_CDC2_CDK1_ST	Q96C36	PYCR2	P06493	CDK1	S233	G236V	236	Missense	distal	3	no	3.541	3.563	EPSD	COSMIC	3.158	Up-regulation
CMGC_CDK_CDC2_CDK1_ST	Q96C36	PYCR2	P06493	CDK1	S233	G235V	235	Missense	proximal	2	no	3.541	3.534	EPSD	COSMIC	3.158	Down-regulation
CMGC_CDK_CDC2_CDK1_ST	Q96C36	PYCR2	P06493	CDK1	T301	S303F	303	Missense	proximal	2	no	3.300	3.322	EPSD	COSMIC	3.158	Up-regulation
CMGC_CDK_CDC2_CDK1_ST	Q96C36	PYCR2	P06493	CDK1	T301	S304N	304	Missense	distal	3	no	3.300	3.305	EPSD	COSMIC	3.158	Up-regulation
CMGC_CDK_CDC2_CDK1_ST	Q96C36	PYCR2	P06493	CDK1	T301	S303N	303	Missense	proximal	2	no	3.300	3.306	EPSD	COSMIC	3.158	Up-regulation
CMGC_CDK_CDC2_CDK1_ST	Q06413	MEF2C	P06493	CDK1	S110	V107I	107	Missense	distal	-3	no	3.200	3.179	EPSD	COSMIC	3.158	Down-regulation
CMGC_CDK_CDC2_CDK1_ST	Q06413	MEF2C	P06493	CDK1	S110	S110C	110	Missense	central	0	yes	3.200	0.000	EPSD	COSMIC	3.158	Loss
CMGC_CDK_CDC2_CDK1_ST	Q06413	MEF2C	P06493	CDK1	S110	S110R	110	Missense	central	0	yes	3.200	0.000	EPSD	COSMIC	3.158	Loss
CMGC_CDK_CDC2_CDK1_ST	Q06413	MEF2C	P06493	CDK1	S110	A103S	103	Missense	distal	-7	no	3.200	3.172	EPSD	COSMIC	3.158	Down-regulation
CMGC_CDK_CDC2_CDK1_ST	Q06413	MEF2C	P06493	CDK1	S110	S106R	106	Missense	distal	-4	no	3.200	3.134	EPSD	COSMIC	3.158	Loss
CMGC_CDK_CDC2_CDK1_ST	Q06413	MEF2C	P06493	CDK1	S110	S106N	106	Missense	distal	-4	no	3.200	3.127	EPSD	COSMIC	3.158	Loss
CMGC_CDK_CDC2_CDK1_ST	Q06413	MEF2C	P06493	CDK1	S110	S106T	106	Missense	distal	-4	no	3.200	3.208	EPSD	COSMIC	3.158	Up-regulation
CMGC_CDK_CDC2_CDK1_ST	Q06413	MEF2C	P06493	CDK1	S110	S106G	106	Missense	distal	-4	no	3.200	3.062	EPSD	COSMIC	3.158	Loss
CMGC_CDK_CDC2_CDK1_ST	Q06413	MEF2C	P06493	CDK1	S183	S181F	181	Missense	proximal	-2	no	3.587	3.654	EPSD	COSMIC	3.158	Up-regulation
CMGC_CDK_CDC2_CDK1_ST	Q06413	MEF2C	P06493	CDK1	S183	L177P	177	Missense	distal	-6	no	3.587	3.560	EPSD	COSMIC	3.158	Down-regulation
CMGC_CDK_CDC2_CDK1_ST	Q06413	MEF2C	P06493	CDK1	S183	N180I	180	Missense	distal	-3	no	3.587	3.563	EPSD	COSMIC	3.158	Down-regulation
CMGC_CDK_CDC2_CDK1_ST	Q06413	MEF2C	P06493	CDK1	S183	G185D	185	Missense	proximal	2	no	3.587	3.574	EPSD	COSMIC	3.158	Down-regulation
CMGC_CDK_CDC2_CDK1_ST	Q06413	MEF2C	P06493	CDK1	S183	S176R	176	Missense	distal	-7	no	3.587	3.551	EPSD	COSMIC	3.158	Down-regulation
CMGC_CDK_CDC2_CDK1_ST	Q06413	MEF2C	P06493	CDK1	S183	M182I	182	Missense	proximal	-1	no	3.587	3.697	EPSD	COSMIC	3.158	Up-regulation
CMGC_CDK_CDC2_CDK1_ST	Q06413	MEF2C	P06493	CDK1	S240	S240P	240	Missense	central	0	yes	3.432	0.000	EPSD	COSMIC	3.158	Loss
CMGC_CDK_CDC2_CDK1_ST	Q06413	MEF2C	P06493	CDK1	S396	S396L	396	Missense	central	0	yes	3.246	0.000	PhosphoSitePlus	COSMIC	3.158	Loss
CMGC_CDK_CDC2_CDK1_ST	Q06413	MEF2C	P06493	CDK1	S396	T402M	402	Missense	distal	6	no	3.246	3.222	PhosphoSitePlus	COSMIC	3.158	Down-regulation
CMGC_CDK_CDC2_CDK1_ST	Q06413	MEF2C	P06493	CDK1	S396	D400Y	400	Missense	distal	4	no	3.246	3.222	PhosphoSitePlus	COSMIC	3.158	Down-regulation
CMGC_CDK_CDC2_CDK1_ST	Q06413	MEF2C	P06493	CDK1	S396	N389S	389	Missense	distal	-7	no	3.246	3.306	PhosphoSitePlus	COSMIC;GDSC	3.158	Up-regulation
CMGC_CDK_CDC2_CDK1_ST	Q06413	MEF2C	P06493	CDK1	S396	I390M	390	Missense	distal	-6	no	3.246	3.234	PhosphoSitePlus	COSMIC	3.158	Down-regulation
CMGC_CDK_CDC2_CDK1_ST	Q06413	MEF2C	P06493	CDK1	S396	R401T	401	Missense	distal	5	no	3.246	3.262	PhosphoSitePlus	COSMIC	3.158	Up-regulation
CMGC_CDK_CDC2_CDK1_ST	Q06413	MEF2C	P06493	CDK1	S396	R401K	401	Missense	distal	5	no	3.246	3.288	PhosphoSitePlus	COSMIC	3.158	Up-regulation
CMGC_CDK_CDC2_CDK1_ST	Q06413	MEF2C	P06493	CDK1	S396	P394R	394	Missense	proximal	-2	no	3.246	3.440	PhosphoSitePlus	COSMIC	3.158	Up-regulation
CMGC_CDK_CDC2_CDK1_ST	Q06413	MEF2C	P06493	CDK1	S396	P394T	394	Missense	proximal	-2	no	3.246	3.334	PhosphoSitePlus	COSMIC	3.158	Up-regulation
CMGC_CDK_CDC2_CDK1_ST	Q06413	MEF2C	P06493	CDK1	S419	R418G	418	Missense	proximal	-1	no	3.126	3.284	EPSD	COSMIC	3.158	Gain
CMGC_CDK_CDC2_CDK1_ST	Q06413	MEF2C	P06493	CDK1	S459	E456K	456	Missense	distal	-3	no	3.170	3.159	EPSD	COSMIC	3.158	Down-regulation
CMGC_CDK_CDC2_CDK1_ST	Q06413	MEF2C	P06493	CDK1	S459	R457T	457	Missense	proximal	-2	no	3.170	3.065	EPSD	COSMIC	3.158	Loss
CMGC_CDK_CDC2_CDK1_ST	Q06413	MEF2C	P06493	CDK1	S459	R464C	464	Missense	distal	5	no	3.170	3.278	EPSD	COSMIC	3.158	Up-regulation
CMGC_CDK_CDC2_CDK1_ST	Q06413	MEF2C	P06493	CDK1	S459	P452H	452	Missense	distal	-7	no	3.170	3.149	EPSD	COSMIC	3.158	Loss
CMGC_CDK_CDC2_CDK1_ST	Q06413	MEF2C	P06493	CDK1	S459	M465I	465	Missense	distal	6	no	3.170	3.143	EPSD	COSMIC	3.158	Loss
CMGC_CDK_CDC2_CDK1_ST	Q06413	MEF2C	P06493	CDK1	S459	S453L	453	Missense	distal	-6	no	3.170	3.199	EPSD	COSMIC	3.158	Up-regulation
CMGC_CDK_CDC2_CDK1_ST	Q06413	MEF2C	P06493	CDK1	S459	E458K	458	Missense	proximal	-1	no	3.170	3.209	EPSD	COSMIC	3.158	Up-regulation
CMGC_CDK_CDC2_CDK1_ST	Q06413	MEF2C	P06493	CDK1	S459	R457K	457	Missense	proximal	-2	no	3.170	3.171	EPSD	COSMIC	3.158	Up-regulation
CMGC_CDK_CDC2_CDK1_ST	Q06413	MEF2C	P06493	CDK1	S459	S459N	459	Missense	central	0	yes	3.170	0.000	EPSD	COSMIC	3.158	Loss
CMGC_CDK_CDC2_CDK1_ST	O43663	PRC1	P06493	CDK1	S513	P519L	519	Missense	distal	6	no	3.253	3.197	EPSD	COSMIC	3.158	Down-regulation
CMGC_CDK_CDC2_CDK1_ST	O43663	PRC1	P06493	CDK1	S513	F506I	506	Missense	distal	-7	no	3.253	3.247	EPSD	COSMIC	3.158	Down-regulation
CMGC_CDK_CDC2_CDK1_ST	O43663	PRC1	P06493	CDK1	S513	G507E	507	Missense	distal	-6	no	3.253	3.239	EPSD	COSMIC;GDSC;CCLE	3.158	Down-regulation
CMGC_CDK_CDC2_CDK1_ST	O43663	PRC1	P06493	CDK1	T536	G543V	543	Missense	distal	7	no	3.465	3.461	EPSD	COSMIC	3.158	Down-regulation
CMGC_CDK_CDC2_CDK1_ST	O75170	PPP6R2	P06493	CDK1	T430	P431L	431	Missense	proximal	1	no	3.440	-0.246	EPSD	COSMIC	3.158	Loss
CMGC_CDK_CDC2_CDK1_ST	P22234	PAICS	P06493	CDK1	S27	G29A	29	Missense	proximal	2	no	3.186	3.156	PhosphoSitePlus	COSMIC	3.158	Loss
CMGC_CDK_CDC2_CDK1_ST	Q6Y7W6	GIGYF2	P06493	CDK1	S593	P594L	594	Missense	proximal	1	no	3.389	-0.298	EPSD	COSMIC	3.158	Loss
CMGC_CDK_CDC2_CDK1_ST	Q6Y7W6	GIGYF2	P06493	CDK1	S593	P600L	600	Missense	distal	7	no	3.389	3.417	EPSD	COSMIC	3.158	Up-regulation
CMGC_CDK_CDC2_CDK1_ST	Q6Y7W6	GIGYF2	P06493	CDK1	S593	P599S	599	Missense	distal	6	no	3.389	3.396	EPSD	COSMIC	3.158	Up-regulation
CMGC_CDK_CDC2_CDK1_ST	Q6Y7W6	GIGYF2	P06493	CDK1	S593	M586L	586	Missense	distal	-7	no	3.389	3.256	EPSD	COSMIC	3.158	Down-regulation
CMGC_CDK_CDC2_CDK1_ST	Q6Y7W6	GIGYF2	P06493	CDK1	S593	P598L	598	Missense	distal	5	no	3.389	3.574	EPSD	COSMIC	3.158	Up-regulation
CMGC_CDK_CDC2_CDK1_ST	Q6Y7W6	GIGYF2	P06493	CDK1	S593	W587C	587	Missense	distal	-6	no	3.389	3.390	EPSD	COSMIC	3.158	Up-regulation
CMGC_CDK_CDC2_CDK1_ST	Q6Y7W6	GIGYF2	P06493	CDK1	S593	P594S	594	Missense	proximal	1	no	3.389	0.204	EPSD	COSMIC	3.158	Loss
CMGC_CDK_CDC2_CDK1_ST	Q6Y7W6	GIGYF2	P06493	CDK1	S593	P591S	591	Missense	proximal	-2	no	3.389	3.515	EPSD	COSMIC	3.158	Up-regulation
CMGC_CDK_CDC2_CDK1_ST	Q6Y7W6	GIGYF2	P06493	CDK1	S593	G595S	595	Missense	proximal	2	no	3.389	3.365	EPSD	COSMIC	3.158	Down-regulation
CMGC_CDK_CDC2_CDK1_ST	Q6Y7W6	GIGYF2	P06493	CDK1	S593	G588R	588	Missense	distal	-5	no	3.389	3.321	EPSD	COSMIC	3.158	Down-regulation
CMGC_CDK_CDC2_CDK1_ST	Q2NKX8	ERCC6L	P06493	CDK1	S14	P8L	8	Missense	distal	-6	no	3.158	3.185	EPSD	COSMIC	3.158	Up-regulation
CMGC_CDK_CDC2_CDK1_ST	Q2NKX8	ERCC6L	P06493	CDK1	S14	L13I	13	Missense	proximal	-1	no	3.158	3.155	EPSD	COSMIC	3.158	Loss
CMGC_CDK_CDC2_CDK1_ST	Q2NKX8	ERCC6L	P06493	CDK1	S946	Q948H	948	Missense	proximal	2	no	3.475	3.484	EPSD	COSMIC	3.158	Up-regulation
CMGC_CDK_CDC2_CDK1_ST	Q2NKX8	ERCC6L	P06493	CDK1	S946	A944E	944	Missense	proximal	-2	no	3.475	3.633	EPSD	COSMIC;GDSC	3.158	Up-regulation
CMGC_CDK_CDC2_CDK1_ST	Q2NKX8	ERCC6L	P06493	CDK1	S946	P947T	947	Missense	proximal	1	no	3.475	1.042	EPSD	COSMIC	3.158	Loss
CMGC_CDK_CDC2_CDK1_ST	Q2NKX8	ERCC6L	P06493	CDK1	S946	P947Q	947	Missense	proximal	1	no	3.475	1.053	EPSD	COSMIC	3.158	Loss
CMGC_CDK_CDC2_CDK1_ST	Q2NKX8	ERCC6L	P06493	CDK1	S1188	Q1184R	1184	Missense	distal	-4	no	3.965	3.947	EPSD	COSMIC	3.158	Down-regulation
CMGC_CDK_CDC2_CDK1_ST	P13051	UNG	P06493	CDK1	S279	Q274L	274	Missense	distal	-5	no	3.049	3.167	EPSD	COSMIC;CCLE	3.158	Gain
CMGC_CDK_CDC2_CDK1_ST	Q9Y5T5	USP16	P06493	CDK1	T217	V210A	210	Missense	distal	-7	no	3.297	3.448	EPSD	COSMIC	3.158	Up-regulation
CMGC_CDK_CDC2_CDK1_ST	Q9Y5T5	USP16	P06493	CDK1	T217	M211I	211	Missense	distal	-6	no	3.297	3.309	EPSD	COSMIC	3.158	Up-regulation
CMGC_CDK_CDC2_CDK1_ST	Q9Y5T5	USP16	P06493	CDK1	T217	V210I	210	Missense	distal	-7	no	3.297	3.269	EPSD	COSMIC	3.158	Down-regulation
CMGC_CDK_CDC2_CDK1_ST	P18858	LIG1	P06493	CDK1	T183	P181S	181	Missense	proximal	-2	no	3.364	3.490	EPSD	COSMIC	3.158	Up-regulation
CMGC_CDK_CDC2_CDK1_ST	P18858	LIG1	P06493	CDK1	T233	F231C	231	Missense	proximal	-2	no	3.337	3.286	EPSD	COSMIC	3.158	Down-regulation
CMGC_CDK_CDC2_CDK1_ST	P18858	LIG1	P06493	CDK1	T233	P234A	234	Missense	proximal	1	no	3.337	2.448	EPSD	COSMIC;GDSC;CCLE	3.158	Loss
CMGC_CDK_CDC2_CDK1_ST	P18858	LIG1	P06493	CDK1	S323	S318I	318	Missense	distal	-5	no	3.431	3.561	EPSD	COSMIC	3.158	Up-regulation
CMGC_CDK_CDC2_CDK1_ST	P18858	LIG1	P06493	CDK1	S535	P539L	539	Missense	distal	4	no	3.617	3.495	EPSD	COSMIC	3.158	Down-regulation
CMGC_CDK_CDC2_CDK1_ST	P26358	DNMT1	P06493	CDK1	T253	P252L	252	Missense	proximal	-1	no	3.744	3.895	EPSD	COSMIC	3.158	Up-regulation
CMGC_CDK_CDC2_CDK1_ST	P26358	DNMT1	P06493	CDK1	T253	R246Q	246	Missense	distal	-7	no	3.744	3.751	EPSD	COSMIC	3.158	Up-regulation
CMGC_CDK_CDC2_CDK1_ST	P26358	DNMT1	P06493	CDK1	T253	P254H	254	Missense	proximal	1	no	3.744	1.060	EPSD	COSMIC	3.158	Loss
CMGC_CDK_CDC2_CDK1_ST	P26358	DNMT1	P06493	CDK1	T253	R246C	246	Missense	distal	-7	no	3.744	3.666	EPSD	COSMIC	3.158	Down-regulation
CMGC_CDK_CDC2_CDK1_ST	P26358	DNMT1	P06493	CDK1	T253	R246H	246	Missense	distal	-7	no	3.744	3.719	EPSD	COSMIC	3.158	Down-regulation
CMGC_CDK_CDC2_CDK1_ST	P26358	DNMT1	P06493	CDK1	S714	P710S	710	Missense	distal	-4	no	3.592	3.643	EPSD	COSMIC	3.158	Up-regulation
CMGC_CDK_CDC2_CDK1_ST	P26358	DNMT1	P06493	CDK1	S714	M712T	712	Missense	proximal	-2	no	3.592	3.535	EPSD	COSMIC;GDSC	3.158	Down-regulation
CMGC_CDK_CDC2_CDK1_ST	P26358	DNMT1	P06493	CDK1	S714	M712L	712	Missense	proximal	-2	no	3.592	3.622	EPSD	COSMIC	3.158	Up-regulation
CMGC_CDK_CDC2_CDK1_ST	P26358	DNMT1	P06493	CDK1	S954	R958C	958	Missense	distal	4	no	3.159	3.095	EPSD	COSMIC	3.158	Loss
CMGC_CDK_CDC2_CDK1_ST	P26358	DNMT1	P06493	CDK1	S954	P955L	955	Missense	proximal	1	no	3.159	-0.527	EPSD	COSMIC	3.158	Loss
CMGC_CDK_CDC2_CDK1_ST	P26358	DNMT1	P06493	CDK1	S954	K961N	961	Missense	distal	7	no	3.159	3.157	EPSD	COSMIC	3.158	Loss
CMGC_CDK_CDC2_CDK1_ST	P26358	DNMT1	P06493	CDK1	S954	R960Q	960	Missense	distal	6	no	3.159	3.142	EPSD	COSMIC	3.158	Loss
CMGC_CDK_CDC2_CDK1_ST	P26358	DNMT1	P06493	CDK1	S954	K951R	951	Missense	distal	-3	no	3.159	3.170	EPSD	COSMIC	3.158	Up-regulation
CMGC_CDK_CDC2_CDK1_ST	P26358	DNMT1	P06493	CDK1	S954	R958H	958	Missense	distal	4	no	3.159	3.118	EPSD	COSMIC	3.158	Loss
CMGC_CDK_CDC2_CDK1_ST	P26358	DNMT1	P06493	CDK1	S954	P959S	959	Missense	distal	5	no	3.159	3.131	EPSD	COSMIC	3.158	Loss
CMGC_CDK_CDC2_CDK1_ST	P26358	DNMT1	P06493	CDK1	S954	T947M	947	Missense	distal	-7	no	3.159	3.071	EPSD	COSMIC	3.158	Loss
CMGC_CDK_CDC2_CDK1_ST	P26358	DNMT1	P06493	CDK1	S954	I950M	950	Missense	distal	-4	no	3.159	3.222	EPSD	COSMIC	3.158	Up-regulation
CMGC_CDK_CDC2_CDK1_ST	O00399	DCTN6	P06493	CDK1	T71	N64H	64	Missense	distal	-7	no	3.921	3.920	EPSD	COSMIC	3.158	Down-regulation
CMGC_CDK_CDC2_CDK1_ST	Q9Y4H2	IRS2	P06493	CDK1	S3	P9R	9	Missense	distal	6	no	3.270	3.284	EPSD	COSMIC	3.158	Up-regulation
CMGC_CDK_CDC2_CDK1_ST	Q9Y4H2	IRS2	P06493	CDK1	S388	P394R	394	Missense	distal	6	no	4.055	4.068	EPSD	COSMIC	3.158	Up-regulation
CMGC_CDK_CDC2_CDK1_ST	Q9Y4H2	IRS2	P06493	CDK1	S491	D494N	494	Missense	distal	3	no	3.116	3.191	EPSD	COSMIC	3.158	Gain
CMGC_CDK_CDC2_CDK1_ST	Q9Y4H2	IRS2	P06493	CDK1	S491	G484S	484	Missense	distal	-7	no	3.116	3.275	EPSD	COSMIC	3.158	Gain
CMGC_CDK_CDC2_CDK1_ST	Q9Y4H2	IRS2	P06493	CDK1	T527	P521L	521	Missense	distal	-6	no	3.374	3.401	EPSD	COSMIC	3.158	Up-regulation
CMGC_CDK_CDC2_CDK1_ST	Q9Y4H2	IRS2	P06493	CDK1	T527	D532G	532	Missense	distal	5	no	3.374	3.468	EPSD	COSMIC	3.158	Up-regulation
CMGC_CDK_CDC2_CDK1_ST	Q9Y4H2	IRS2	P06493	CDK1	T527	P528S	528	Missense	proximal	1	no	3.374	0.189	EPSD	COSMIC	3.158	Loss
CMGC_CDK_CDC2_CDK1_ST	Q9Y4H2	IRS2	P06493	CDK1	T527	E526K	526	Missense	proximal	-1	no	3.374	3.413	EPSD	COSMIC	3.158	Up-regulation
CMGC_CDK_CDC2_CDK1_ST	Q9Y4H2	IRS2	P06493	CDK1	T657	M656V	656	Missense	proximal	-1	no	3.213	3.271	EPSD	COSMIC;CCLE	3.158	Up-regulation
CMGC_CDK_CDC2_CDK1_ST	Q9Y4H2	IRS2	P06493	CDK1	T657	G652S	652	Missense	distal	-5	no	3.213	3.088	EPSD	COSMIC	3.158	Loss
CMGC_CDK_CDC2_CDK1_ST	Q9Y4H2	IRS2	P06493	CDK1	T657	P658H	658	Missense	proximal	1	no	3.213	0.529	EPSD	COSMIC	3.158	Loss
CMGC_CDK_CDC2_CDK1_ST	Q9Y4H2	IRS2	P06493	CDK1	T657	L662V	662	Missense	distal	5	no	3.213	3.150	EPSD	COSMIC	3.158	Loss
CMGC_CDK_CDC2_CDK1_ST	Q9Y4H2	IRS2	P06493	CDK1	T657	A663V	663	Missense	distal	6	no	3.213	3.166	EPSD	COSMIC	3.158	Down-regulation
CMGC_CDK_CDC2_CDK1_ST	Q9Y4H2	IRS2	P06493	CDK1	S731	A729S	729	Missense	proximal	-2	no	3.053	3.173	EPSD	COSMIC	3.158	Gain
CMGC_CDK_CDC2_CDK1_ST	Q9Y4H2	IRS2	P06493	CDK1	S736	A729S	729	Missense	distal	-7	no	3.437	3.410	EPSD	COSMIC	3.158	Down-regulation
CMGC_CDK_CDC2_CDK1_ST	Q9Y4H2	IRS2	P06493	CDK1	S736	Y742H	742	Missense	distal	6	no	3.437	3.463	EPSD	COSMIC	3.158	Up-regulation
CMGC_CDK_CDC2_CDK1_ST	Q9Y4H2	IRS2	P06493	CDK1	S736	S730R	730	Missense	distal	-6	no	3.437	3.444	EPSD	COSMIC	3.158	Up-regulation
CMGC_CDK_CDC2_CDK1_ST	Q9Y4H2	IRS2	P06493	CDK1	S736	P737L	737	Missense	proximal	1	no	3.437	-0.249	EPSD	COSMIC	3.158	Loss
CMGC_CDK_CDC2_CDK1_ST	Q9Y4H2	IRS2	P06493	CDK1	T844	A843V	843	Missense	proximal	-1	no	3.324	3.523	EPSD	COSMIC	3.158	Up-regulation
CMGC_CDK_CDC2_CDK1_ST	Q9Y4H2	IRS2	P06493	CDK1	T844	E840Q	840	Missense	distal	-4	no	3.324	3.335	EPSD	COSMIC	3.158	Up-regulation
CMGC_CDK_CDC2_CDK1_ST	Q9Y4H2	IRS2	P06493	CDK1	S915	G917S	917	Missense	proximal	2	no	3.283	3.260	EPSD	COSMIC	3.158	Down-regulation
CMGC_CDK_CDC2_CDK1_ST	Q9Y4H2	IRS2	P06493	CDK1	S915	E912G	912	Missense	distal	-3	no	3.283	3.255	EPSD	COSMIC	3.158	Down-regulation
CMGC_CDK_CDC2_CDK1_ST	Q9Y4H2	IRS2	P06493	CDK1	S915	P908S	908	Missense	distal	-7	no	3.283	3.323	EPSD	COSMIC	3.158	Up-regulation
CMGC_CDK_CDC2_CDK1_ST	Q9Y4H2	IRS2	P06493	CDK1	S915	E918A	918	Missense	distal	3	no	3.283	3.387	EPSD	COSMIC	3.158	Up-regulation
CMGC_CDK_CDC2_CDK1_ST	Q9Y4H2	IRS2	P06493	CDK1	S932	P937L	937	Missense	distal	5	no	3.013	3.197	EPSD	COSMIC	3.158	Gain
CMGC_CDK_CDC2_CDK1_ST	Q9Y4H2	IRS2	P06493	CDK1	S985	L981H	981	Missense	distal	-4	no	3.353	3.478	EPSD	COSMIC	3.158	Up-regulation
CMGC_CDK_CDC2_CDK1_ST	Q9Y4H2	IRS2	P06493	CDK1	S985	S988F	988	Missense	distal	3	no	3.353	3.222	EPSD	COSMIC	3.158	Down-regulation
CMGC_CDK_CDC2_CDK1_ST	Q9Y4H2	IRS2	P06493	CDK1	S985	S988C	988	Missense	distal	3	no	3.353	3.305	EPSD	COSMIC	3.158	Down-regulation
CMGC_CDK_CDC2_CDK1_ST	Q9Y4H2	IRS2	P06493	CDK1	T1082	A1089P	1089	Missense	distal	7	no	3.332	3.344	EPSD	COSMIC;CCLE	3.158	Up-regulation
CMGC_CDK_CDC2_CDK1_ST	Q9Y4H2	IRS2	P06493	CDK1	T1082	A1088V	1088	Missense	distal	6	no	3.332	3.284	EPSD	COSMIC;CCLE	3.158	Down-regulation
CMGC_CDK_CDC2_CDK1_ST	Q9Y4H2	IRS2	P06493	CDK1	T1082	P1083L	1083	Missense	proximal	1	no	3.332	-0.355	EPSD	COSMIC	3.158	Loss
CMGC_CDK_CDC2_CDK1_ST	Q9Y4H2	IRS2	P06493	CDK1	S1237	G1230S	1230	Missense	distal	-7	no	3.116	3.275	EPSD	COSMIC;GDSC;CCLE	3.158	Gain
CMGC_CDK_CDC2_CDK1_ST	Q9Y4H2	IRS2	P06493	CDK1	S1237	E1242V	1242	Missense	distal	5	no	3.116	3.186	EPSD	COSMIC;GDSC;CCLE	3.158	Gain
CMGC_CDK_CDC2_CDK1_ST	Q8TF76	HASPIN	P06493	CDK1	T112	A105S	105	Missense	distal	-7	no	3.346	3.319	EPSD	COSMIC	3.158	Down-regulation
CMGC_CDK_CDC2_CDK1_ST	Q8TF76	HASPIN	P06493	CDK1	T112	G117W	117	Missense	distal	5	no	3.346	3.266	EPSD	COSMIC	3.158	Down-regulation
CMGC_CDK_CDC2_CDK1_ST	Q8TF76	HASPIN	P06493	CDK1	T112	A105T	105	Missense	distal	-7	no	3.346	3.339	EPSD	COSMIC	3.158	Down-regulation
CMGC_CDK_CDC2_CDK1_ST	Q8TF76	HASPIN	P06493	CDK1	T112	L116Q	116	Missense	distal	4	no	3.346	3.464	EPSD	COSMIC	3.158	Up-regulation
CMGC_CDK_CDC2_CDK1_ST	Q8TF76	HASPIN	P06493	CDK1	S179	D184N	184	Missense	distal	5	no	3.187	3.139	EPSD	COSMIC	3.158	Loss
CMGC_CDK_CDC2_CDK1_ST	Q8TF76	HASPIN	P06493	CDK1	S179	S174L	174	Missense	distal	-5	no	3.187	3.330	EPSD	COSMIC	3.158	Up-regulation
CMGC_CDK_CDC2_CDK1_ST	Q8TF76	HASPIN	P06493	CDK1	S179	P177S	177	Missense	proximal	-2	no	3.187	3.313	EPSD	COSMIC	3.158	Up-regulation
CMGC_CDK_CDC2_CDK1_ST	Q8TF76	HASPIN	P06493	CDK1	S179	V186A	186	Missense	distal	7	no	3.187	3.153	EPSD	COSMIC	3.158	Loss
CMGC_CDK_CDC2_CDK1_ST	Q8TF76	HASPIN	P06493	CDK1	S179	V186L	186	Missense	distal	7	no	3.187	3.193	EPSD	COSMIC	3.158	Up-regulation
CMGC_CDK_CDC2_CDK1_ST	Q8TF76	HASPIN	P06493	CDK1	T373	V378I	378	Missense	distal	5	no	3.379	3.393	EPSD	COSMIC	3.158	Up-regulation
CMGC_CDK_CDC2_CDK1_ST	Q8TF76	HASPIN	P06493	CDK1	T373	F367I	367	Missense	distal	-6	no	3.379	3.378	EPSD	COSMIC	3.158	Down-regulation
CMGC_CDK_CDC2_CDK1_ST	Q8TF76	HASPIN	P06493	CDK1	T373	P374S	374	Missense	proximal	1	no	3.379	0.194	EPSD	COSMIC	3.158	Loss
CMGC_CDK_CDC2_CDK1_ST	Q8TF76	HASPIN	P06493	CDK1	T373	V378A	378	Missense	distal	5	no	3.379	3.172	EPSD	COSMIC	3.158	Down-regulation
CMGC_CDK_CDC2_CDK1_ST	Q8TF76	HASPIN	P06493	CDK1	T373	D371E	371	Missense	proximal	-2	no	3.379	3.399	EPSD	COSMIC	3.158	Up-regulation
CMGC_CDK_CDC2_CDK1_ST	Q8TF76	HASPIN	P06493	CDK1	T373	S366L	366	Missense	distal	-7	no	3.379	3.178	EPSD	COSMIC	3.158	Down-regulation
CMGC_CDK_CDC2_CDK1_ST	Q8TF76	HASPIN	P06493	CDK1	T373	V378L	378	Missense	distal	5	no	3.379	3.442	EPSD	COSMIC	3.158	Up-regulation
CMGC_CDK_CDC2_CDK1_ST	Q8WX93	PALLD	P06493	CDK1	T100	E107Q	107	Missense	distal	7	no	3.428	3.418	EPSD	COSMIC	3.158	Down-regulation
CMGC_CDK_CDC2_CDK1_ST	Q8WX93	PALLD	P06493	CDK1	T147	V152I	152	Missense	distal	5	no	3.491	3.505	EPSD	COSMIC	3.158	Up-regulation
CMGC_CDK_CDC2_CDK1_ST	Q8WX93	PALLD	P06493	CDK1	T147	R143H	143	Missense	distal	-4	no	3.491	3.487	EPSD	COSMIC	3.158	Down-regulation
CMGC_CDK_CDC2_CDK1_ST	Q8WX93	PALLD	P06493	CDK1	S401	G405R	405	Missense	distal	4	no	3.036	3.161	EPSD	COSMIC	3.158	Gain
CMGC_CDK_CDC2_CDK1_ST	Q8WX93	PALLD	P06493	CDK1	S484	G478R	478	Missense	distal	-6	no	3.166	3.151	EPSD	COSMIC	3.158	Loss
CMGC_CDK_CDC2_CDK1_ST	Q8WX93	PALLD	P06493	CDK1	S484	R488Q	488	Missense	distal	4	no	3.166	3.148	EPSD	COSMIC	3.158	Loss
CMGC_CDK_CDC2_CDK1_ST	Q8WX93	PALLD	P06493	CDK1	S484	G478V	478	Missense	distal	-6	no	3.166	3.163	EPSD	COSMIC	3.158	Down-regulation
CMGC_CDK_CDC2_CDK1_ST	Q8WX93	PALLD	P06493	CDK1	S484	G478W	478	Missense	distal	-6	no	3.166	3.158	EPSD	COSMIC	3.158	Down-regulation
CMGC_CDK_CDC2_CDK1_ST	O60285	NUAK1	P06493	CDK1	S22	G29E	29	Missense	distal	7	no	3.211	3.197	EPSD	COSMIC	3.158	Down-regulation
CMGC_CDK_CDC2_CDK1_ST	O60285	NUAK1	P06493	CDK1	S22	A19G	19	Missense	distal	-3	no	3.211	3.114	EPSD	COSMIC	3.158	Loss
CMGC_CDK_CDC2_CDK1_ST	O60285	NUAK1	P06493	CDK1	S455	P456S	456	Missense	proximal	1	no	3.500	0.315	EPSD	COSMIC	3.158	Loss
CMGC_CDK_CDC2_CDK1_ST	O60285	NUAK1	P06493	CDK1	S542	P546H	546	Missense	distal	4	no	3.304	3.277	EPSD	COSMIC	3.158	Down-regulation
CMGC_CDK_CDC2_CDK1_ST	O60285	NUAK1	P06493	CDK1	S542	M536I	536	Missense	distal	-6	no	3.304	3.317	EPSD	COSMIC	3.158	Up-regulation
CMGC_CDK_CDC2_CDK1_ST	P61020	RAB5B	P06493	CDK1	S196	R197P	197	Missense	proximal	1	no	-0.314	3.295	EPSD	COSMIC	3.158	Gain
CMGC_CDK_CDC2_CDK1_ST	P20338	RAB4A	P06493	CDK1	S204	A198V	198	Missense	distal	-6	no	3.259	3.280	PhosphoSitePlus	COSMIC	3.158	Up-regulation
CMGC_CDK_CDC2_CDK1_ST	P20338	RAB4A	P06493	CDK1	S204	R206Q	206	Missense	proximal	2	no	3.259	3.255	PhosphoSitePlus	COSMIC	3.158	Down-regulation
CMGC_CDK_CDC2_CDK1_ST	P20338	RAB4A	P06493	CDK1	S204	A208S	208	Missense	distal	4	no	3.259	3.199	PhosphoSitePlus	COSMIC	3.158	Down-regulation
CMGC_CDK_CDC2_CDK1_ST	Q8IXJ6	SIRT2	P06493	CDK1	T280	S274F	274	Missense	distal	-6	no	3.535	3.559	EPSD	COSMIC	3.158	Up-regulation
CMGC_CDK_CDC2_CDK1_ST	Q8IXJ6	SIRT2	P06493	CDK1	T280	S279F	279	Missense	proximal	-1	no	3.535	3.688	EPSD	COSMIC	3.158	Up-regulation
CMGC_CDK_CDC2_CDK1_ST	Q8IXJ6	SIRT2	P06493	CDK1	T280	R282H	282	Missense	proximal	2	no	3.535	3.540	EPSD	COSMIC;GDSC;CCLE	3.158	Up-regulation
CMGC_CDK_CDC2_CDK1_ST	Q8IXJ6	SIRT2	P06493	CDK1	T280	R282C	282	Missense	proximal	2	no	3.535	3.542	EPSD	COSMIC;GDSC;CCLE	3.158	Up-regulation
CMGC_CDK_CDC2_CDK1_ST	Q8IXJ6	SIRT2	P06493	CDK1	T280	K275N	275	Missense	distal	-5	no	3.535	3.499	EPSD	COSMIC;GDSC	3.158	Down-regulation
CMGC_CDK_CDC2_CDK1_ST	Q9H9S0	NANOG	P06493	CDK1	S65	S69P	69	Missense	distal	4	no	3.327	3.330	EPSD;PhosphoSitePlus	COSMIC	3.158	Up-regulation
CMGC_CDK_CDC2_CDK1_ST	Q9H9S0	NANOG	P06493	CDK1	S65	S65N	65	Missense	central	0	yes	3.327	0.000	EPSD;PhosphoSitePlus	COSMIC	3.158	Loss
CMGC_CDK_CDC2_CDK1_ST	Q8NFH8	REPS2	P06493	CDK1	S191	S198F	198	Missense	distal	7	no	3.464	3.487	EPSD	COSMIC	3.158	Up-regulation
CMGC_CDK_CDC2_CDK1_ST	Q8NFH8	REPS2	P06493	CDK1	S191	M190L	190	Missense	proximal	-1	no	3.464	3.578	EPSD	COSMIC	3.158	Up-regulation
CMGC_CDK_CDC2_CDK1_ST	Q8NFH8	REPS2	P06493	CDK1	S191	P196S	196	Missense	distal	5	no	3.464	3.436	EPSD	COSMIC	3.158	Down-regulation
CMGC_CDK_CDC2_CDK1_ST	Q8NFH8	REPS2	P06493	CDK1	S191	Q186H	186	Missense	distal	-5	no	3.464	3.492	EPSD	COSMIC	3.158	Up-regulation
CMGC_CDK_CDC2_CDK1_ST	P23396	RPS3	P06493	CDK1	T42	P43S	43	Missense	proximal	1	no	3.626	0.442	EPSD	COSMIC	3.158	Loss
CMGC_CDK_CDC2_CDK1_ST	P04637	TP53	P06493	CDK1	S33	M40I	40	Missense	distal	7	no	3.447	3.462	EPSD	COSMIC	3.158	Up-regulation
CMGC_CDK_CDC2_CDK1_ST	P04637	TP53	P06493	CDK1	S33	V31I	31	Missense	proximal	-2	no	3.447	3.495	EPSD	COSMIC;GDSC;CCLE	3.158	Up-regulation
CMGC_CDK_CDC2_CDK1_ST	P04637	TP53	P06493	CDK1	S33	P36L	36	Missense	distal	3	no	3.447	3.314	EPSD	COSMIC;GDSC;CCLE	3.158	Down-regulation
CMGC_CDK_CDC2_CDK1_ST	P04637	TP53	P06493	CDK1	S33	Q38L	38	Missense	distal	5	no	3.447	3.646	EPSD	COSMIC	3.158	Up-regulation
CMGC_CDK_CDC2_CDK1_ST	P04637	TP53	P06493	CDK1	S33	S37T	37	Missense	distal	4	no	3.447	3.455	EPSD	COSMIC	3.158	Up-regulation
CMGC_CDK_CDC2_CDK1_ST	P04637	TP53	P06493	CDK1	S33	L26P	26	Missense	distal	-7	no	3.447	3.608	EPSD	COSMIC	3.158	Up-regulation
CMGC_CDK_CDC2_CDK1_ST	P04637	TP53	P06493	CDK1	S33	P36S	36	Missense	distal	3	no	3.447	3.497	EPSD	COSMIC;GDSC;CCLE	3.158	Up-regulation
CMGC_CDK_CDC2_CDK1_ST	P04637	TP53	P06493	CDK1	S33	A39V	39	Missense	distal	6	no	3.447	3.399	EPSD	COSMIC	3.158	Down-regulation
CMGC_CDK_CDC2_CDK1_ST	P04637	TP53	P06493	CDK1	S33	A39S	39	Missense	distal	6	no	3.447	3.437	EPSD	COSMIC	3.158	Down-regulation
CMGC_CDK_CDC2_CDK1_ST	P04637	TP53	P06493	CDK1	S33	N30K	30	Missense	distal	-3	no	3.447	3.426	EPSD	COSMIC	3.158	Down-regulation
CMGC_CDK_CDC2_CDK1_ST	P04637	TP53	P06493	CDK1	S33	A39T	39	Missense	distal	6	no	3.447	3.439	EPSD	COSMIC	3.158	Down-regulation
CMGC_CDK_CDC2_CDK1_ST	P04637	TP53	P06493	CDK1	S33	P27T	27	Missense	distal	-6	no	3.447	3.444	EPSD	COSMIC	3.158	Down-regulation
CMGC_CDK_CDC2_CDK1_ST	P04637	TP53	P06493	CDK1	S33	P36R	36	Missense	distal	3	no	3.447	3.568	EPSD	COSMIC	3.158	Up-regulation
CMGC_CDK_CDC2_CDK1_ST	P04637	TP53	P06493	CDK1	S33	L35R	35	Missense	proximal	2	no	3.447	3.432	EPSD	COSMIC	3.158	Down-regulation
CMGC_CDK_CDC2_CDK1_ST	P04637	TP53	P06493	CDK1	S33	L35H	35	Missense	proximal	2	no	3.447	3.437	EPSD	COSMIC	3.158	Down-regulation
CMGC_CDK_CDC2_CDK1_ST	P04637	TP53	P06493	CDK1	S33	L35P	35	Missense	proximal	2	no	3.447	3.427	EPSD	COSMIC	3.158	Down-regulation
CMGC_CDK_CDC2_CDK1_ST	P04637	TP53	P06493	CDK1	S33	L35I	35	Missense	proximal	2	no	3.447	3.446	EPSD	COSMIC	3.158	Down-regulation
CMGC_CDK_CDC2_CDK1_ST	P04637	TP53	P06493	CDK1	S33	L35V	35	Missense	proximal	2	no	3.447	3.441	EPSD	COSMIC	3.158	Down-regulation
CMGC_CDK_CDC2_CDK1_ST	P04637	TP53	P06493	CDK1	T81	P77A	77	Missense	distal	-4	no	3.467	3.491	EPSD	COSMIC	3.158	Up-regulation
CMGC_CDK_CDC2_CDK1_ST	P04637	TP53	P06493	CDK1	T81	A76T	76	Missense	distal	-5	no	3.467	3.489	EPSD	COSMIC	3.158	Up-regulation
CMGC_CDK_CDC2_CDK1_ST	P04637	TP53	P06493	CDK1	T81	A83T	83	Missense	proximal	2	no	3.467	3.474	EPSD	COSMIC	3.158	Up-regulation
CMGC_CDK_CDC2_CDK1_ST	P04637	TP53	P06493	CDK1	T81	T81I	81	Missense	central	0	yes	3.467	0.000	EPSD	COSMIC	3.158	Loss
CMGC_CDK_CDC2_CDK1_ST	P04637	TP53	P06493	CDK1	T81	A84V	84	Missense	distal	3	no	3.467	3.314	EPSD	COSMIC	3.158	Down-regulation
CMGC_CDK_CDC2_CDK1_ST	P04637	TP53	P06493	CDK1	T81	P80L	80	Missense	proximal	-1	no	3.467	3.617	EPSD	COSMIC	3.158	Up-regulation
CMGC_CDK_CDC2_CDK1_ST	P04637	TP53	P06493	CDK1	T81	A86V	86	Missense	distal	5	no	3.467	3.674	EPSD	COSMIC	3.158	Up-regulation
CMGC_CDK_CDC2_CDK1_ST	P04637	TP53	P06493	CDK1	T81	P85S	85	Missense	distal	4	no	3.467	3.464	EPSD	COSMIC	3.158	Down-regulation
CMGC_CDK_CDC2_CDK1_ST	P04637	TP53	P06493	CDK1	T81	A79T	79	Missense	proximal	-2	no	3.467	3.548	EPSD	COSMIC	3.158	Up-regulation
CMGC_CDK_CDC2_CDK1_ST	P04637	TP53	P06493	CDK1	T81	A84G	84	Missense	distal	3	no	3.467	3.292	EPSD	COSMIC	3.158	Down-regulation
CMGC_CDK_CDC2_CDK1_ST	P04637	TP53	P06493	CDK1	T81	A78V	78	Missense	distal	-3	no	3.467	3.406	EPSD	COSMIC	3.158	Down-regulation
CMGC_CDK_CDC2_CDK1_ST	P04637	TP53	P06493	CDK1	T81	A78S	78	Missense	distal	-3	no	3.467	3.425	EPSD	COSMIC	3.158	Down-regulation
CMGC_CDK_CDC2_CDK1_ST	P04637	TP53	P06493	CDK1	T81	P87L	87	Missense	distal	6	no	3.467	3.411	EPSD	COSMIC	3.158	Down-regulation
CMGC_CDK_CDC2_CDK1_ST	P04637	TP53	P06493	CDK1	T81	P85L	85	Missense	distal	4	no	3.467	3.345	EPSD	COSMIC	3.158	Down-regulation
CMGC_CDK_CDC2_CDK1_ST	P04637	TP53	P06493	CDK1	T81	P82S	82	Missense	proximal	1	no	3.467	0.283	EPSD	COSMIC	3.158	Loss
CMGC_CDK_CDC2_CDK1_ST	P04637	TP53	P06493	CDK1	T81	P77S	77	Missense	distal	-4	no	3.467	3.518	EPSD	COSMIC	3.158	Up-regulation
CMGC_CDK_CDC2_CDK1_ST	P04637	TP53	P06493	CDK1	T81	P80S	80	Missense	proximal	-1	no	3.467	3.416	EPSD	COSMIC	3.158	Down-regulation
CMGC_CDK_CDC2_CDK1_ST	P04637	TP53	P06493	CDK1	T81	A84T	84	Missense	distal	3	no	3.467	3.380	EPSD	COSMIC	3.158	Down-regulation
CMGC_CDK_CDC2_CDK1_ST	P04637	TP53	P06493	CDK1	T81	A83E	83	Missense	proximal	2	no	3.467	3.483	EPSD	COSMIC	3.158	Up-regulation
CMGC_CDK_CDC2_CDK1_ST	P04637	TP53	P06493	CDK1	T81	P85T	85	Missense	distal	4	no	3.467	3.472	EPSD	COSMIC	3.158	Up-regulation
CMGC_CDK_CDC2_CDK1_ST	P04637	TP53	P06493	CDK1	T81	A74V	74	Missense	distal	-7	no	3.467	3.316	EPSD	COSMIC	3.158	Down-regulation
CMGC_CDK_CDC2_CDK1_ST	P04637	TP53	P06493	CDK1	T81	P75S	75	Missense	distal	-6	no	3.467	3.466	EPSD	COSMIC	3.158	Down-regulation
CMGC_CDK_CDC2_CDK1_ST	P04637	TP53	P06493	CDK1	T81	A76V	76	Missense	distal	-5	no	3.467	3.607	EPSD	COSMIC	3.158	Up-regulation
CMGC_CDK_CDC2_CDK1_ST	P04637	TP53	P06493	CDK1	T81	P75R	75	Missense	distal	-6	no	3.467	3.473	EPSD	COSMIC	3.158	Up-regulation
CMGC_CDK_CDC2_CDK1_ST	P04637	TP53	P06493	CDK1	T81	P87H	87	Missense	distal	6	no	3.467	3.462	EPSD	COSMIC	3.158	Down-regulation
CMGC_CDK_CDC2_CDK1_ST	P04637	TP53	P06493	CDK1	T81	P87T	87	Missense	distal	6	no	3.467	3.477	EPSD	COSMIC	3.158	Up-regulation
CMGC_CDK_CDC2_CDK1_ST	P04637	TP53	P06493	CDK1	T81	P87S	87	Missense	distal	6	no	3.467	3.475	EPSD	COSMIC	3.158	Up-regulation
CMGC_CDK_CDC2_CDK1_ST	P04637	TP53	P06493	CDK1	T81	P87R	87	Missense	distal	6	no	3.467	3.481	EPSD	COSMIC	3.158	Up-regulation
CMGC_CDK_CDC2_CDK1_ST	P04637	TP53	P06493	CDK1	T81	P87C	87	Missense	distal	6	no	3.467	3.443	EPSD	COSMIC	3.158	Down-regulation
CMGC_CDK_CDC2_CDK1_ST	P04637	TP53	P06493	CDK1	T81	A86E	86	Missense	distal	5	no	3.467	3.605	EPSD	COSMIC	3.158	Up-regulation
CMGC_CDK_CDC2_CDK1_ST	P04637	TP53	P06493	CDK1	T81	A86S	86	Missense	distal	5	no	3.467	3.524	EPSD	COSMIC	3.158	Up-regulation
CMGC_CDK_CDC2_CDK1_ST	P04637	TP53	P06493	CDK1	T81	A83V	83	Missense	proximal	2	no	3.467	3.490	EPSD	COSMIC	3.158	Up-regulation
CMGC_CDK_CDC2_CDK1_ST	Q8NEB9	PIK3C3	P06493	CDK1	T159	E155K	155	Missense	distal	-4	no	3.411	3.358	PhosphoSitePlus	COSMIC	3.158	Down-regulation
CMGC_CDK_CDC2_CDK1_ST	Q8NEB9	PIK3C3	P06493	CDK1	T159	S154L	154	Missense	distal	-5	no	3.411	3.555	PhosphoSitePlus	COSMIC	3.158	Up-regulation
CMGC_CDK_CDC2_CDK1_ST	Q8NEB9	PIK3C3	P06493	CDK1	T159	P160F	160	Missense	proximal	1	no	3.411	-0.475	PhosphoSitePlus	COSMIC	3.158	Loss
CMGC_CDK_CDC2_CDK1_ST	Q8NEB9	PIK3C3	P06493	CDK1	T159	P160A	160	Missense	proximal	1	no	3.411	2.522	PhosphoSitePlus	COSMIC	3.158	Loss
CMGC_CDK_CDC2_CDK1_ST	Q8NEB9	PIK3C3	P06493	CDK1	S448	T447S	447	Missense	proximal	-1	no	3.168	3.195	EPSD	COSMIC	3.158	Up-regulation
CMGC_CDK_CDC2_CDK1_ST	Q8NEB9	PIK3C3	P06493	CDK1	S448	S455L	455	Missense	distal	7	no	3.168	3.198	EPSD	COSMIC	3.158	Up-regulation
CMGC_CDK_CDC2_CDK1_ST	Q8NEB9	PIK3C3	P06493	CDK1	S448	S442C	442	Missense	distal	-6	no	3.168	3.185	EPSD	COSMIC	3.158	Up-regulation
CMGC_CDK_CDC2_CDK1_ST	Q8NEB9	PIK3C3	P06493	CDK1	S448	D441V	441	Missense	distal	-7	no	3.168	3.104	EPSD	COSMIC;GDSC;CCLE	3.158	Loss
CMGC_CDK_CDC2_CDK1_ST	Q8NEB9	PIK3C3	P06493	CDK1	S455	S455L	455	Missense	central	0	yes	3.630	0.000	EPSD	COSMIC	3.158	Loss
CMGC_CDK_CDC2_CDK1_ST	Q8NEB9	PIK3C3	P06493	CDK1	T668	D664N	664	Missense	distal	-4	no	3.601	3.587	EPSD	COSMIC	3.158	Down-regulation
CMGC_CDK_CDC2_CDK1_ST	Q8NEB9	PIK3C3	P06493	CDK1	T668	Y670C	670	Missense	proximal	2	no	3.601	3.599	EPSD	COSMIC;GDSC;CCLE	3.158	Down-regulation
CMGC_CDK_CDC2_CDK1_ST	Q8TD19	NEK9	P06493	CDK1	T358	W352L	352	Missense	distal	-6	no	3.298	3.311	EPSD	COSMIC	3.158	Up-regulation
CMGC_CDK_CDC2_CDK1_ST	Q8TD19	NEK9	P06493	CDK1	T358	T358P	358	Missense	central	0	yes	3.298	0.000	EPSD	COSMIC	3.158	Loss
CMGC_CDK_CDC2_CDK1_ST	Q8TD19	NEK9	P06493	CDK1	T771	F778L	778	Missense	distal	7	no	3.249	3.257	EPSD	COSMIC	3.158	Up-regulation
CMGC_CDK_CDC2_CDK1_ST	Q8TD19	NEK9	P06493	CDK1	S793	G787E	787	Missense	distal	-6	no	3.343	3.330	EPSD	COSMIC	3.158	Down-regulation
CMGC_CDK_CDC2_CDK1_ST	Q8TD19	NEK9	P06493	CDK1	S793	I792M	792	Missense	proximal	-1	no	3.343	3.233	EPSD	COSMIC	3.158	Down-regulation
CMGC_CDK_CDC2_CDK1_ST	Q8TD19	NEK9	P06493	CDK1	T883	P888S	888	Missense	distal	5	no	3.168	3.139	EPSD	COSMIC	3.158	Loss
CMGC_CDK_CDC2_CDK1_ST	Q8TD19	NEK9	P06493	CDK1	T883	T877I	877	Missense	distal	-6	no	3.168	3.192	EPSD	COSMIC	3.158	Up-regulation
CMGC_CDK_CDC2_CDK1_ST	Q8TD19	NEK9	P06493	CDK1	T886	P888S	888	Missense	proximal	2	no	4.291	4.289	EPSD	COSMIC	3.158	Down-regulation
CMGC_CDK_CDC2_CDK1_ST	Q8TD19	NEK9	P06493	CDK1	T886	C892Y	892	Missense	distal	6	no	4.291	4.284	EPSD	COSMIC	3.158	Down-regulation
CMGC_CDK_CDC2_CDK1_ST	Q06481	APLP2	P06493	CDK1	T736	E739D	739	Missense	distal	3	no	3.591	3.573	PhosphoSitePlus	COSMIC	3.158	Down-regulation
CMGC_CDK_CDC2_CDK1_ST	Q06481	APLP2	P06493	CDK1	T736	R740C	740	Missense	distal	4	no	3.591	3.527	PhosphoSitePlus	COSMIC	3.158	Down-regulation
CMGC_CDK_CDC2_CDK1_ST	Q96Q89	KIF20B	P06493	CDK1	S38	H39P	39	Missense	proximal	1	no	0.556	3.241	EPSD	COSMIC	3.158	Gain
CMGC_CDK_CDC2_CDK1_ST	Q96Q89	KIF20B	P06493	CDK1	T1675	P1676S	1676	Missense	proximal	1	no	3.162	-0.023	EPSD	COSMIC	3.158	Loss
CMGC_CDK_CDC2_CDK1_ST	Q96Q89	KIF20B	P06493	CDK1	T1675	N1670T	1670	Missense	distal	-5	no	3.162	3.112	EPSD	COSMIC	3.158	Loss
CMGC_CDK_CDC2_CDK1_ST	Q96Q89	KIF20B	P06493	CDK1	T1675	T1678S	1678	Missense	distal	3	no	3.162	3.196	EPSD	COSMIC	3.158	Up-regulation
CMGC_CDK_CDC2_CDK1_ST	Q02952	AKAP12	P06493	CDK1	S283	S278N	278	Missense	distal	-5	no	3.124	3.172	EPSD	COSMIC	3.158	Gain
CMGC_CDK_CDC2_CDK1_ST	Q02952	AKAP12	P06493	CDK1	S483	D485H	485	Missense	proximal	2	no	3.493	3.494	EPSD	COSMIC	3.158	Up-regulation
CMGC_CDK_CDC2_CDK1_ST	Q02952	AKAP12	P06493	CDK1	S483	V488G	488	Missense	distal	5	no	3.493	3.525	EPSD	COSMIC	3.158	Up-regulation
CMGC_CDK_CDC2_CDK1_ST	Q02952	AKAP12	P06493	CDK1	S483	P476H	476	Missense	distal	-7	no	3.493	3.471	EPSD	COSMIC	3.158	Down-regulation
CMGC_CDK_CDC2_CDK1_ST	Q02952	AKAP12	P06493	CDK1	S514	K518T	518	Missense	distal	4	no	3.926	3.947	EPSD	COSMIC	3.158	Up-regulation
CMGC_CDK_CDC2_CDK1_ST	Q02952	AKAP12	P06493	CDK1	S514	R508I	508	Missense	distal	-6	no	3.926	3.941	EPSD	COSMIC	3.158	Up-regulation
CMGC_CDK_CDC2_CDK1_ST	Q02952	AKAP12	P06493	CDK1	S743	A747V	747	Missense	distal	4	no	3.622	3.486	EPSD	COSMIC	3.158	Down-regulation
CMGC_CDK_CDC2_CDK1_ST	Q02952	AKAP12	P06493	CDK1	T767	S772L	772	Missense	distal	5	no	3.239	3.452	PhosphoSitePlus	COSMIC	3.158	Up-regulation
CMGC_CDK_CDC2_CDK1_ST	Q02952	AKAP12	P06493	CDK1	T767	V766D	766	Missense	proximal	-1	no	3.239	3.178	PhosphoSitePlus	COSMIC	3.158	Down-regulation
CMGC_CDK_CDC2_CDK1_ST	Q02952	AKAP12	P06493	CDK1	T767	R764W	764	Missense	distal	-3	no	3.239	3.238	PhosphoSitePlus	COSMIC	3.158	Down-regulation
CMGC_CDK_CDC2_CDK1_ST	Q02952	AKAP12	P06493	CDK1	T767	K770T	770	Missense	distal	3	no	3.239	3.151	PhosphoSitePlus	COSMIC	3.158	Loss
CMGC_CDK_CDC2_CDK1_ST	Q02952	AKAP12	P06493	CDK1	S1012	P1013R	1013	Missense	proximal	1	no	3.194	-0.415	EPSD	COSMIC	3.158	Loss
CMGC_CDK_CDC2_CDK1_ST	Q02952	AKAP12	P06493	CDK1	S1328	A1326G	1326	Missense	proximal	-2	no	2.984	3.193	EPSD	COSMIC	3.158	Gain
CMGC_CDK_CDC2_CDK1_ST	Q02952	AKAP12	P06493	CDK1	S1395	P1397H	1397	Missense	proximal	2	no	3.393	3.403	EPSD	COSMIC	3.158	Up-regulation
CMGC_CDK_CDC2_CDK1_ST	Q02952	AKAP12	P06493	CDK1	S1395	P1396L	1396	Missense	proximal	1	no	3.393	-0.294	EPSD	COSMIC	3.158	Loss
CMGC_CDK_CDC2_CDK1_ST	Q02952	AKAP12	P06493	CDK1	S1395	E1388K	1388	Missense	distal	-7	no	3.393	3.348	EPSD	COSMIC	3.158	Down-regulation
CMGC_CDK_CDC2_CDK1_ST	Q02952	AKAP12	P06493	CDK1	S1395	V1389I	1389	Missense	distal	-6	no	3.393	3.396	EPSD	COSMIC	3.158	Up-regulation
CMGC_CDK_CDC2_CDK1_ST	Q02952	AKAP12	P06493	CDK1	S1395	L1392F	1392	Missense	distal	-3	no	3.393	3.397	EPSD	COSMIC	3.158	Up-regulation
CMGC_CDK_CDC2_CDK1_ST	Q02952	AKAP12	P06493	CDK1	S1727	K1734E	1734	Missense	distal	7	no	3.563	3.567	EPSD	COSMIC	3.158	Up-regulation
CMGC_CDK_CDC2_CDK1_ST	Q02952	AKAP12	P06493	CDK1	S1727	P1728L	1728	Missense	proximal	1	no	3.563	-0.124	EPSD	COSMIC	3.158	Loss
CMGC_CDK_CDC2_CDK1_ST	Q02952	AKAP12	P06493	CDK1	S1727	P1728R	1728	Missense	proximal	1	no	3.563	-0.046	EPSD	COSMIC	3.158	Loss
AGC_PKG_PRKG1_ST	P04792	HSPB1	Q13976-2	PRKG1	S15	P14S	14	Missense	proximal	-1	no	10.333	10.437	EPSD;PhosphoSitePlus	COSMIC	7.092	Up-regulation
AGC_PKG_PRKG1_ST	P04792	HSPB1	Q13976-2	PRKG1	S15	R20W	20	Missense	distal	5	no	10.333	10.233	EPSD;PhosphoSitePlus	COSMIC	7.092	Down-regulation
AGC_PKG_PRKG1_ST	P04792	HSPB1	Q13976-2	PRKG1	S15	R20Q	20	Missense	distal	5	no	10.333	10.309	EPSD;PhosphoSitePlus	COSMIC	7.092	Down-regulation
AGC_PKG_PRKG1_ST	P04792	HSPB1	Q13976-2	PRKG1	S15	F8L	8	Missense	distal	-7	no	10.333	9.595	EPSD;PhosphoSitePlus	COSMIC	7.092	Down-regulation
AGC_PKG_PRKG1_ST	P04792	HSPB1	Q13976-2	PRKG1	S78	R75C	75	Missense	distal	-3	no	11.052	4.030	PhosphoSitePlus;EPSD	COSMIC	7.092	Loss
AGC_PKG_PRKG1_ST	P04792	HSPB1	Q13976-2	PRKG1	S82	R75C	75	Missense	distal	-7	no	12.536	11.108	EPSD;PhosphoSitePlus	COSMIC	7.092	Down-regulation
AGC_PKG_PRKG1_ST	P04792	HSPB1	Q13976-2	PRKG1	T143	R140Q	140	Missense	distal	-3	no	10.597	6.762	EPSD;PhosphoSitePlus	COSMIC	7.092	Loss
AGC_PKG_PRKG1_ST	Q13976	PRKG1	Q13976-2	PRKG1	S27	K20E	20	Missense	distal	-7	no	10.846	9.845	EPSD	COSMIC	7.092	Down-regulation
AGC_PKG_PRKG1_ST	Q13976	PRKG1	Q13976-2	PRKG1	T59	G63D	63	Missense	distal	4	no	8.128	8.151	EPSD	COSMIC	7.092	Up-regulation
AGC_PKG_PRKG1_ST	Q13976	PRKG1	Q13976-2	PRKG1	S65	G63D	63	Missense	proximal	-2	no	8.252	5.837	EPSD;PhosphoSitePlus	COSMIC	7.092	Loss
AGC_PKG_PRKG1_ST	Q13976	PRKG1	Q13976-2	PRKG1	S273	N267S	267	Missense	distal	-6	no	7.247	7.529	EPSD	COSMIC	7.092	Up-regulation
AGC_PKG_PRKG1_ST	Q13976	PRKG1	Q13976-2	PRKG1	S273	N267Y	267	Missense	distal	-6	no	7.247	7.165	EPSD	COSMIC	7.092	Down-regulation
AGC_PKG_PRKG1_ST	Q13976	PRKG1	Q13976-2	PRKG1	S273	E271V	271	Missense	proximal	-2	no	7.247	8.289	EPSD	COSMIC	7.092	Up-regulation
AGC_PKG_PRKG1_ST	Q13976	PRKG1	Q13976-2	PRKG1	S273	D277Y	277	Missense	distal	4	no	7.247	7.263	EPSD	COSMIC	7.092	Up-regulation
AGC_PKG_PRKG1_ST	Q13976	PRKG1	Q13976-2	PRKG1	S273	P278Q	278	Missense	distal	5	no	7.247	7.318	EPSD	COSMIC	7.092	Up-regulation
AGC_PKG_PRKG1_ST	Q13976	PRKG1	Q13976-2	PRKG1	S273	V279F	279	Missense	distal	6	no	7.247	7.211	EPSD	COSMIC	7.092	Down-regulation
AGC_PKG_PRKG1_ST	Q13976	PRKG1	Q13976-2	PRKG1	S273	E276K	276	Missense	distal	3	no	7.247	7.074	EPSD	COSMIC;CCLE	7.092	Loss
AGC_PKG_PRKG1_ST	Q13976	PRKG1	Q13976-2	PRKG1	S273	R270H	270	Missense	distal	-3	no	7.247	1.180	EPSD	COSMIC	7.092	Loss
AGC_PKG_PRKG1_ST	Q13976	PRKG1	Q13976-2	PRKG1	S273	P274L	274	Missense	proximal	1	no	7.247	7.017	EPSD	COSMIC;CCLE	7.092	Loss
AGC_PKG_PRKG1_ST	Q13976	PRKG1	Q13976-2	PRKG1	S273	P278T	278	Missense	distal	5	no	7.247	7.314	EPSD	COSMIC	7.092	Up-regulation
AGC_PKG_PRKG1_ST	Q13976	PRKG1	Q13976-2	PRKG1	S273	R270S	270	Missense	distal	-3	no	7.247	1.759	EPSD	COSMIC	7.092	Loss
AGC_PKG_PRKG1_ST	Q13976	PRKG1	Q13976-2	PRKG1	S273	V268I	268	Missense	distal	-5	no	7.247	7.350	EPSD	COSMIC	7.092	Up-regulation
AGC_PKG_PRKG1_ST	Q13976	PRKG1	Q13976-2	PRKG1	T515	G512R	512	Missense	distal	-3	no	4.463	9.053	EPSD	COSMIC	7.092	Gain
AGC_PKG_PRKG1_ST	Q13153	PAK1	Q13976-2	PRKG1	S21	T20I	20	Missense	proximal	-1	no	8.946	8.747	PhosphoSitePlus	COSMIC	7.092	Down-regulation
AGC_PKG_PRKG1_ST	Q13153	PAK1	Q13976-2	PRKG1	S21	M17I	17	Missense	distal	-4	no	8.946	8.240	PhosphoSitePlus	COSMIC	7.092	Down-regulation
AGC_PKG_PRKG1_ST	Q13153	PAK1	Q13976-2	PRKG1	S137	S133L	133	Missense	distal	-4	no	8.034	7.261	EPSD	COSMIC	7.092	Down-regulation
AGC_PKG_PRKG1_ST	Q13153	PAK1	Q13976-2	PRKG1	S137	S133P	133	Missense	distal	-4	no	8.034	7.610	EPSD	COSMIC	7.092	Down-regulation
AGC_PKG_PRKG1_ST	Q13153	PAK1	Q13976-2	PRKG1	S137	K141E	141	Missense	distal	4	no	8.034	8.149	EPSD	COSMIC	7.092	Up-regulation
AGC_PKG_PRKG1_ST	Q13153	PAK1	Q13976-2	PRKG1	S137	Y142C	142	Missense	distal	5	no	8.034	8.044	EPSD	COSMIC	7.092	Up-regulation
AGC_PKG_PRKG1_ST	Q13153	PAK1	Q13976-2	PRKG1	S144	E151K	151	Missense	distal	7	no	7.065	7.149	EPSD	COSMIC	7.092	Gain
AGC_PKG_PRKG1_ST	Q13153	PAK1	Q13976-2	PRKG1	S249	K245R	245	Missense	distal	-4	no	8.062	8.366	EPSD	COSMIC	7.092	Up-regulation
AGC_PKG_PRKG1_ST	Q13153	PAK1	Q13976-2	PRKG1	S249	K243Q	243	Missense	distal	-6	no	8.062	7.930	EPSD	COSMIC	7.092	Down-regulation
AGC_PKG_PRKG1_ST	Q13153	PAK1	Q13976-2	PRKG1	S249	D250H	250	Missense	proximal	1	no	8.062	8.236	EPSD	COSMIC	7.092	Up-regulation
AGC_PKG_PRKG1_ST	Q13153	PAK1	Q13976-2	PRKG1	S249	E251K	251	Missense	proximal	2	no	8.062	8.113	EPSD	COSMIC	7.092	Up-regulation
AGC_PKG_PRKG1_ST	Q13153	PAK1	Q13976-2	PRKG1	T271	R272W	272	Missense	proximal	1	no	7.347	6.777	EPSD	COSMIC	7.092	Loss
AGC_PKG_PRKG1_ST	Q13153	PAK1	Q13976-2	PRKG1	T271	E274K	274	Missense	distal	3	no	7.347	7.174	EPSD	COSMIC	7.092	Down-regulation
AGC_PKG_PRKG1_ST	Q13153	PAK1	Q13976-2	PRKG1	S422	R421W	421	Missense	proximal	-1	no	9.274	9.017	EPSD	COSMIC	7.092	Down-regulation
AGC_PKG_PRKG1_ST	Q13153	PAK1	Q13976-2	PRKG1	S422	P428L	428	Missense	distal	6	no	9.274	9.402	EPSD	COSMIC	7.092	Up-regulation
AGC_PKG_PRKG1_ST	Q13153	PAK1	Q13976-2	PRKG1	S422	R421Q	421	Missense	proximal	-1	no	9.274	9.209	EPSD	COSMIC	7.092	Down-regulation
AGC_PKG_PRKG1_ST	Q13153	PAK1	Q13976-2	PRKG1	S422	M424I	424	Missense	proximal	2	no	9.274	9.188	EPSD	COSMIC	7.092	Down-regulation
AGC_PKG_PRKG1_ST	Q13153	PAK1	Q13976-2	PRKG1	S422	E417V	417	Missense	distal	-5	no	9.274	9.264	EPSD	COSMIC	7.092	Down-regulation
AGC_PKG_PRKG1_ST	Q13153	PAK1	Q13976-2	PRKG1	S422	R421K	421	Missense	proximal	-1	no	9.274	9.215	EPSD	COSMIC	7.092	Down-regulation
AGC_PKG_PRKG1_ST	Q13153	PAK1	Q13976-2	PRKG1	T423	R421W	421	Missense	proximal	-2	no	8.832	3.501	EPSD	COSMIC	7.092	Loss
AGC_PKG_PRKG1_ST	Q13153	PAK1	Q13976-2	PRKG1	T423	P428L	428	Missense	distal	5	no	8.832	8.788	EPSD	COSMIC	7.092	Down-regulation
AGC_PKG_PRKG1_ST	Q13153	PAK1	Q13976-2	PRKG1	T423	R421Q	421	Missense	proximal	-2	no	8.832	5.867	EPSD	COSMIC	7.092	Loss
AGC_PKG_PRKG1_ST	Q13153	PAK1	Q13976-2	PRKG1	T423	M424I	424	Missense	proximal	1	no	8.832	8.474	EPSD	COSMIC	7.092	Down-regulation
AGC_PKG_PRKG1_ST	Q13153	PAK1	Q13976-2	PRKG1	T423	E417V	417	Missense	distal	-6	no	8.832	8.800	EPSD	COSMIC	7.092	Down-regulation
AGC_PKG_PRKG1_ST	Q13153	PAK1	Q13976-2	PRKG1	T423	R421K	421	Missense	proximal	-2	no	8.832	7.354	EPSD	COSMIC	7.092	Down-regulation
AGC_PKG_PRKG1_ST	Q13153	PAK1	Q13976-2	PRKG1	S511	R509K	509	Missense	proximal	-2	no	10.380	8.902	EPSD	COSMIC	7.092	Down-regulation
AGC_PKG_PRKG1_ST	Q13153	PAK1	Q13976-2	PRKG1	S511	A512V	512	Missense	proximal	1	no	10.380	10.057	EPSD	COSMIC	7.092	Down-regulation
AGC_PKG_PRKG1_ST	Q13153	PAK1	Q13976-2	PRKG1	S511	K508N	508	Missense	distal	-3	no	10.380	5.833	EPSD	COSMIC	7.092	Loss
AGC_PKG_PRKG1_ST	Q13153	PAK1	Q13976-2	PRKG1	S528	S528F	528	Missense	central	0	yes	8.202	0.000	EPSD	COSMIC	7.092	Loss
AGC_PKG_PRKG1_ST	Q13153	PAK1	Q13976-2	PRKG1	S528	L533M	533	Missense	distal	5	no	8.202	8.312	EPSD	COSMIC	7.092	Up-regulation
AGC_PKG_PRKG1_ST	Q14847	LASP1	Q13976-2	PRKG1	S61	A55T	55	Missense	distal	-6	no	7.442	7.403	EPSD	COSMIC	7.092	Down-regulation
AGC_PKG_PRKG1_ST	Q14847	LASP1	Q13976-2	PRKG1	S61	M64L	64	Missense	distal	3	no	7.442	7.775	EPSD	COSMIC	7.092	Up-regulation
AGC_PKG_PRKG1_ST	Q14847	LASP1	Q13976-2	PRKG1	S61	T63S	63	Missense	proximal	2	no	7.442	7.474	EPSD	COSMIC	7.092	Up-regulation
AGC_PKG_PRKG1_ST	Q14847	LASP1	Q13976-2	PRKG1	S61	M64T	64	Missense	distal	3	no	7.442	7.398	EPSD	COSMIC	7.092	Down-regulation
AGC_PKG_PRKG1_ST	Q14847	LASP1	Q13976-2	PRKG1	S99	D103E	103	Missense	distal	4	no	7.566	7.553	EPSD	COSMIC	7.092	Down-regulation
AGC_PKG_PRKG1_ST	Q14847	LASP1	Q13976-2	PRKG1	S99	S99I	99	Missense	central	0	yes	7.566	0.000	EPSD	COSMIC	7.092	Loss
AGC_PKG_PRKG1_ST	Q14847	LASP1	Q13976-2	PRKG1	S146	E140Q	140	Missense	distal	-6	no	12.899	13.247	PhosphoSitePlus	COSMIC	7.092	Up-regulation
AGC_PKG_PRKG1_ST	Q14847	LASP1	Q13976-2	PRKG1	S146	R153W	153	Missense	distal	7	no	12.899	12.745	PhosphoSitePlus	COSMIC;GDSC	7.092	Down-regulation
AGC_PKG_PRKG1_ST	Q14847	LASP1	Q13976-2	PRKG1	S146	R144L	144	Missense	proximal	-2	no	12.899	7.605	PhosphoSitePlus	COSMIC	7.092	Down-regulation
AGC_PKG_PRKG1_ST	Q14847	LASP1	Q13976-2	PRKG1	S146	G149D	149	Missense	distal	3	no	12.899	12.941	PhosphoSitePlus	COSMIC	7.092	Up-regulation
STE_STE20_PAKB_PAK4_ST	O43623	SNAI2	O96013	PAK4	S100	H99Q	99	Missense	proximal	-1	no	17.763	16.801	EPSD	COSMIC	14.946	Down-regulation
STE_STE20_PAKB_PAK4_ST	O43623	SNAI2	O96013	PAK4	S100	D98N	98	Missense	proximal	-2	no	17.763	17.672	EPSD	COSMIC;GDSC;CCLE	14.946	Down-regulation
STE_STE20_PAKB_PAK4_ST	O43623	SNAI2	O96013	PAK4	S100	G101D	101	Missense	proximal	1	no	17.763	17.577	EPSD	COSMIC	14.946	Down-regulation
STE_STE20_PAKB_PAK4_ST	O43623	SNAI2	O96013	PAK4	S170	A173S	173	Missense	distal	3	no	15.232	14.374	EPSD	COSMIC	14.946	Loss
STE_STE20_PAKB_PAK4_ST	O43623	SNAI2	O96013	PAK4	S247	N245D	245	Missense	proximal	-2	no	15.232	15.323	EPSD	COSMIC	14.946	Up-regulation
STE_STE20_PAKB_PAK4_ST	O43623	SNAI2	O96013	PAK4	S247	S251C	251	Missense	distal	4	no	15.232	15.678	EPSD	COSMIC	14.946	Up-regulation
STE_STE20_PAKB_PAK4_ST	O43623	SNAI2	O96013	PAK4	S251	N245D	245	Missense	distal	-6	no	18.576	18.590	EPSD	COSMIC	14.946	Up-regulation
STE_STE20_PAKB_PAK4_ST	O43623	SNAI2	O96013	PAK4	S251	K258N	258	Missense	distal	7	no	18.576	18.785	EPSD	COSMIC;GDSC;CCLE	14.946	Up-regulation
STE_STE20_PAKB_PAK4_ST	O43623	SNAI2	O96013	PAK4	S251	L255P	255	Missense	distal	4	no	18.576	17.878	EPSD	COSMIC	14.946	Down-regulation
STE_STE20_PAKB_PAK4_ST	O43623	SNAI2	O96013	PAK4	S251	S251C	251	Missense	central	0	yes	18.576	0.000	EPSD	COSMIC	14.946	Loss
STE_STE20_PAKB_PAK4_ST	O96013	PAK4	O96013	PAK4	S99	R96H	96	Missense	distal	-3	no	17.891	13.885	EPSD	COSMIC	14.946	Loss
STE_STE20_PAKB_PAK4_ST	O96013	PAK4	O96013	PAK4	S99	S93F	93	Missense	distal	-6	no	17.891	17.806	EPSD	COSMIC	14.946	Down-regulation
STE_STE20_PAKB_PAK4_ST	O96013	PAK4	O96013	PAK4	S99	P106S	106	Missense	distal	7	no	17.891	17.585	EPSD	COSMIC	14.946	Down-regulation
STE_STE20_PAKB_PAK4_ST	O96013	PAK4	O96013	PAK4	S99	R101Q	101	Missense	proximal	2	no	17.891	18.557	EPSD	COSMIC	14.946	Up-regulation
STE_STE20_PAKB_PAK4_ST	O96013	PAK4	O96013	PAK4	S104	A109T	109	Missense	distal	5	no	16.271	16.317	EPSD	COSMIC	14.946	Up-regulation
STE_STE20_PAKB_PAK4_ST	O96013	PAK4	O96013	PAK4	S104	P106S	106	Missense	proximal	2	no	16.271	16.867	EPSD	COSMIC	14.946	Up-regulation
STE_STE20_PAKB_PAK4_ST	O96013	PAK4	O96013	PAK4	S104	R101Q	101	Missense	distal	-3	no	16.271	10.747	EPSD	COSMIC	14.946	Loss
STE_STE20_PAKB_PAK4_ST	O96013	PAK4	O96013	PAK4	S142	R137W	137	Missense	distal	-5	no	15.389	14.452	EPSD	COSMIC	14.946	Loss
STE_STE20_PAKB_PAK4_ST	O96013	PAK4	O96013	PAK4	S142	A139T	139	Missense	distal	-3	no	15.389	12.531	EPSD	COSMIC	14.946	Loss
STE_STE20_PAKB_PAK4_ST	O96013	PAK4	O96013	PAK4	S142	R137C	137	Missense	distal	-5	no	15.389	14.466	EPSD	COSMIC	14.946	Loss
STE_STE20_PAKB_PAK4_ST	O96013	PAK4	O96013	PAK4	S162	R164Q	164	Missense	proximal	2	no	19.330	19.996	EPSD	COSMIC	14.946	Up-regulation
STE_STE20_PAKB_PAK4_ST	O96013	PAK4	O96013	PAK4	S163	R164Q	164	Missense	proximal	1	no	15.855	15.428	EPSD	COSMIC	14.946	Down-regulation
STE_STE20_PAKB_PAK4_ST	O96013	PAK4	O96013	PAK4	S167	R164Q	164	Missense	distal	-3	no	17.668	12.145	EPSD	COSMIC	14.946	Loss
STE_STE20_PAKB_PAK4_ST	O96013	PAK4	O96013	PAK4	S217	P216T	216	Missense	proximal	-1	no	15.691	16.030	EPSD	COSMIC	14.946	Up-regulation
STE_STE20_PAKB_PAK4_ST	O96013	PAK4	O96013	PAK4	S217	E223V	223	Missense	distal	6	no	15.691	15.712	EPSD	COSMIC	14.946	Up-regulation
STE_STE20_PAKB_PAK4_ST	O96013	PAK4	O96013	PAK4	S217	E223K	223	Missense	distal	6	no	15.691	15.493	EPSD	COSMIC	14.946	Down-regulation
STE_STE20_PAKB_PAK4_ST	O96013	PAK4	O96013	PAK4	S217	P224T	224	Missense	distal	7	no	15.691	15.469	EPSD	COSMIC	14.946	Down-regulation
STE_STE20_PAKB_PAK4_ST	O96013	PAK4	O96013	PAK4	S246	R252Q	252	Missense	distal	6	no	15.674	16.067	EPSD	COSMIC;GDSC;CCLE	14.946	Up-regulation
STE_STE20_PAKB_PAK4_ST	O96013	PAK4	O96013	PAK4	S246	R248Q	248	Missense	proximal	2	no	15.674	16.340	EPSD	COSMIC	14.946	Up-regulation
STE_STE20_PAKB_PAK4_ST	O96013	PAK4	O96013	PAK4	S247	R252Q	252	Missense	distal	5	no	16.474	16.365	EPSD	COSMIC;GDSC;CCLE	14.946	Down-regulation
STE_STE20_PAKB_PAK4_ST	O96013	PAK4	O96013	PAK4	S247	R248Q	248	Missense	proximal	1	no	16.474	16.047	EPSD	COSMIC	14.946	Down-regulation
STE_STE20_PAKB_PAK4_ST	O96013	PAK4	O96013	PAK4	S474	R471Q	471	Missense	distal	-3	no	31.770	26.246	PhosphoSitePlus	COSMIC	14.946	Down-regulation
STE_STE20_PAKB_PAK4_ST	O96013	PAK4	O96013	PAK4	S474	P479S	479	Missense	distal	5	no	31.770	31.782	PhosphoSitePlus	COSMIC	14.946	Up-regulation
STE_STE20_PAKB_PAK4_ST	O96013	PAK4	O96013	PAK4	S474	G477D	477	Missense	distal	3	no	31.770	32.110	PhosphoSitePlus	COSMIC	14.946	Up-regulation
STE_STE20_PAKB_PAK4_ST	P35222	CTNNB1	O96013	PAK4	S23	V22I	22	Missense	proximal	-1	no	14.118	15.136	EPSD	COSMIC	14.946	Gain
STE_STE20_PAKB_PAK4_ST	P35222	CTNNB1	O96013	PAK4	S23	V22A	22	Missense	proximal	-1	no	14.118	16.903	EPSD	COSMIC	14.946	Gain
STE_STE20_PAKB_PAK4_ST	P35222	CTNNB1	O96013	PAK4	S37	P44S	44	Missense	distal	7	no	15.702	15.396	EPSD	COSMIC	14.946	Down-regulation
STE_STE20_PAKB_PAK4_ST	P35222	CTNNB1	O96013	PAK4	S37	A43V	43	Missense	distal	6	no	15.702	15.868	EPSD	COSMIC	14.946	Up-regulation
STE_STE20_PAKB_PAK4_ST	P35222	CTNNB1	O96013	PAK4	S37	A39G	39	Missense	proximal	2	no	15.702	15.079	EPSD	COSMIC	14.946	Down-regulation
STE_STE20_PAKB_PAK4_ST	P35222	CTNNB1	O96013	PAK4	S37	G38A	38	Missense	proximal	1	no	15.702	15.795	EPSD	COSMIC	14.946	Up-regulation
STE_STE20_PAKB_PAK4_ST	P35222	CTNNB1	O96013	PAK4	S37	T40I	40	Missense	distal	3	no	15.702	16.125	EPSD	COSMIC	14.946	Up-regulation
STE_STE20_PAKB_PAK4_ST	P35222	CTNNB1	O96013	PAK4	S37	P44A	44	Missense	distal	7	no	15.702	15.510	EPSD	COSMIC	14.946	Down-regulation
STE_STE20_PAKB_PAK4_ST	P35222	CTNNB1	O96013	PAK4	S37	I35T	35	Missense	proximal	-2	no	15.702	13.866	EPSD	COSMIC	14.946	Loss
STE_STE20_PAKB_PAK4_ST	P35222	CTNNB1	O96013	PAK4	S37	T41P	41	Missense	distal	4	no	15.702	15.578	EPSD	COSMIC	14.946	Down-regulation
STE_STE20_PAKB_PAK4_ST	P35222	CTNNB1	O96013	PAK4	S37	T42R	42	Missense	distal	5	no	15.702	15.766	EPSD	COSMIC	14.946	Up-regulation
STE_STE20_PAKB_PAK4_ST	P35222	CTNNB1	O96013	PAK4	S37	D32E	32	Missense	distal	-5	no	15.702	15.783	EPSD	COSMIC	14.946	Up-regulation
STE_STE20_PAKB_PAK4_ST	P35222	CTNNB1	O96013	PAK4	S37	H36R	36	Missense	proximal	-1	no	15.702	18.081	EPSD	COSMIC	14.946	Up-regulation
STE_STE20_PAKB_PAK4_ST	P35222	CTNNB1	O96013	PAK4	S37	T40A	40	Missense	distal	3	no	15.702	16.335	EPSD	COSMIC	14.946	Up-regulation
STE_STE20_PAKB_PAK4_ST	P35222	CTNNB1	O96013	PAK4	S37	A43T	43	Missense	distal	6	no	15.702	15.768	EPSD	COSMIC	14.946	Up-regulation
STE_STE20_PAKB_PAK4_ST	P35222	CTNNB1	O96013	PAK4	S37	P44L	44	Missense	distal	7	no	15.702	15.768	EPSD	COSMIC	14.946	Up-regulation
STE_STE20_PAKB_PAK4_ST	P35222	CTNNB1	O96013	PAK4	S37	G34L	34	Missense	distal	-3	no	15.702	17.337	EPSD	COSMIC	14.946	Up-regulation
STE_STE20_PAKB_PAK4_ST	P35222	CTNNB1	O96013	PAK4	S37	T42I	42	Missense	distal	5	no	15.702	15.524	EPSD	COSMIC	14.946	Down-regulation
STE_STE20_PAKB_PAK4_ST	P35222	CTNNB1	O96013	PAK4	S37	S33L	33	Missense	distal	-4	no	15.702	12.610	EPSD	COSMIC;CCLE	14.946	Loss
STE_STE20_PAKB_PAK4_ST	P35222	CTNNB1	O96013	PAK4	S37	T42S	42	Missense	distal	5	no	15.702	15.662	EPSD	COSMIC	14.946	Down-regulation
STE_STE20_PAKB_PAK4_ST	P35222	CTNNB1	O96013	PAK4	S37	T42K	42	Missense	distal	5	no	15.702	15.780	EPSD	COSMIC	14.946	Up-regulation
STE_STE20_PAKB_PAK4_ST	P35222	CTNNB1	O96013	PAK4	S37	L31P	31	Missense	distal	-6	no	15.702	15.836	EPSD	COSMIC	14.946	Up-regulation
STE_STE20_PAKB_PAK4_ST	P35222	CTNNB1	O96013	PAK4	S37	S37L	37	Missense	central	0	yes	15.702	0.000	EPSD	COSMIC	14.946	Loss
STE_STE20_PAKB_PAK4_ST	P35222	CTNNB1	O96013	PAK4	S37	A39T	39	Missense	proximal	2	no	15.702	15.148	EPSD	COSMIC	14.946	Down-regulation
STE_STE20_PAKB_PAK4_ST	P35222	CTNNB1	O96013	PAK4	S37	S33N	33	Missense	distal	-4	no	15.702	14.202	EPSD	COSMIC	14.946	Loss
STE_STE20_PAKB_PAK4_ST	P35222	CTNNB1	O96013	PAK4	S37	H36Y	36	Missense	proximal	-1	no	15.702	15.382	EPSD	COSMIC	14.946	Down-regulation
STE_STE20_PAKB_PAK4_ST	P35222	CTNNB1	O96013	PAK4	S37	A43P	43	Missense	distal	6	no	15.702	15.885	EPSD	COSMIC	14.946	Up-regulation
STE_STE20_PAKB_PAK4_ST	P35222	CTNNB1	O96013	PAK4	S37	Y30C	30	Missense	distal	-7	no	15.702	14.162	EPSD	COSMIC	14.946	Loss
STE_STE20_PAKB_PAK4_ST	P35222	CTNNB1	O96013	PAK4	S37	G38P	38	Missense	proximal	1	no	15.702	14.485	EPSD	COSMIC	14.946	Loss
STE_STE20_PAKB_PAK4_ST	P35222	CTNNB1	O96013	PAK4	S37	G38D	38	Missense	proximal	1	no	15.702	15.516	EPSD	COSMIC	14.946	Down-regulation
STE_STE20_PAKB_PAK4_ST	P35222	CTNNB1	O96013	PAK4	S37	T42A	42	Missense	distal	5	no	15.702	15.655	EPSD	COSMIC	14.946	Down-regulation
STE_STE20_PAKB_PAK4_ST	P35222	CTNNB1	O96013	PAK4	S37	I35M	35	Missense	proximal	-2	no	15.702	17.463	EPSD	COSMIC	14.946	Up-regulation
STE_STE20_PAKB_PAK4_ST	P35222	CTNNB1	O96013	PAK4	S37	T40S	40	Missense	distal	3	no	15.702	15.477	EPSD	COSMIC	14.946	Down-regulation
STE_STE20_PAKB_PAK4_ST	P35222	CTNNB1	O96013	PAK4	S37	G34A	34	Missense	distal	-3	no	15.702	17.667	EPSD	COSMIC	14.946	Up-regulation
STE_STE20_PAKB_PAK4_ST	P35222	CTNNB1	O96013	PAK4	S37	L31W	31	Missense	distal	-6	no	15.702	15.761	EPSD	COSMIC	14.946	Up-regulation
STE_STE20_PAKB_PAK4_ST	P35222	CTNNB1	O96013	PAK4	S37	T41S	41	Missense	distal	4	no	15.702	15.491	EPSD	COSMIC	14.946	Down-regulation
STE_STE20_PAKB_PAK4_ST	P35222	CTNNB1	O96013	PAK4	S37	G34I	34	Missense	distal	-3	no	15.702	17.095	EPSD	COSMIC	14.946	Up-regulation
STE_STE20_PAKB_PAK4_ST	P35222	CTNNB1	O96013	PAK4	S37	I35N	35	Missense	proximal	-2	no	15.702	14.691	EPSD	COSMIC	14.946	Loss
STE_STE20_PAKB_PAK4_ST	P35222	CTNNB1	O96013	PAK4	S37	T42Q	42	Missense	distal	5	no	15.702	15.658	EPSD	COSMIC	14.946	Down-regulation
STE_STE20_PAKB_PAK4_ST	P35222	CTNNB1	O96013	PAK4	S37	D32C	32	Missense	distal	-5	no	15.702	15.497	EPSD	COSMIC	14.946	Down-regulation
STE_STE20_PAKB_PAK4_ST	P35222	CTNNB1	O96013	PAK4	S37	Y30S	30	Missense	distal	-7	no	15.702	16.648	EPSD	COSMIC	14.946	Up-regulation
STE_STE20_PAKB_PAK4_ST	P35222	CTNNB1	O96013	PAK4	S37	L31M	31	Missense	distal	-6	no	15.702	15.949	EPSD	COSMIC	14.946	Up-regulation
STE_STE20_PAKB_PAK4_ST	P35222	CTNNB1	O96013	PAK4	S37	A39V	39	Missense	proximal	2	no	15.702	15.195	EPSD	COSMIC	14.946	Down-regulation
STE_STE20_PAKB_PAK4_ST	P35222	CTNNB1	O96013	PAK4	S37	L31Q	31	Missense	distal	-6	no	15.702	15.876	EPSD	COSMIC	14.946	Up-regulation
STE_STE20_PAKB_PAK4_ST	P35222	CTNNB1	O96013	PAK4	S37	G34D	34	Missense	distal	-3	no	15.702	16.363	EPSD	COSMIC	14.946	Up-regulation
STE_STE20_PAKB_PAK4_ST	P35222	CTNNB1	O96013	PAK4	S37	I35K	35	Missense	proximal	-2	no	15.702	19.668	EPSD	COSMIC	14.946	Up-regulation
STE_STE20_PAKB_PAK4_ST	P35222	CTNNB1	O96013	PAK4	S37	D32F	32	Missense	distal	-5	no	15.702	16.037	EPSD	COSMIC	14.946	Up-regulation
STE_STE20_PAKB_PAK4_ST	P35222	CTNNB1	O96013	PAK4	S37	G38X	38	Missense	proximal	1	no	15.702	16.350	EPSD	COSMIC	14.946	Up-regulation
STE_STE20_PAKB_PAK4_ST	P35222	CTNNB1	O96013	PAK4	S37	D32X	32	Missense	distal	-5	no	15.702	15.699	EPSD	COSMIC	14.946	Down-regulation
STE_STE20_PAKB_PAK4_ST	P35222	CTNNB1	O96013	PAK4	S37	S33K	33	Missense	distal	-4	no	15.702	15.418	EPSD	COSMIC	14.946	Down-regulation
STE_STE20_PAKB_PAK4_ST	P35222	CTNNB1	O96013	PAK4	S37	I35V	35	Missense	proximal	-2	no	15.702	13.529	EPSD	COSMIC	14.946	Loss
STE_STE20_PAKB_PAK4_ST	P35222	CTNNB1	O96013	PAK4	S37	G34C	34	Missense	distal	-3	no	15.702	14.427	EPSD	COSMIC	14.946	Loss
STE_STE20_PAKB_PAK4_ST	P35222	CTNNB1	O96013	PAK4	S37	G38S	38	Missense	proximal	1	no	15.702	16.186	EPSD	COSMIC	14.946	Up-regulation
STE_STE20_PAKB_PAK4_ST	P35222	CTNNB1	O96013	PAK4	S37	S37V	37	Missense	central	0	yes	15.702	0.000	EPSD	COSMIC	14.946	Loss
STE_STE20_PAKB_PAK4_ST	P35222	CTNNB1	O96013	PAK4	S37	P44I	44	Missense	distal	7	no	15.702	15.626	EPSD	COSMIC	14.946	Down-regulation
STE_STE20_PAKB_PAK4_ST	P35222	CTNNB1	O96013	PAK4	S37	I35F	35	Missense	proximal	-2	no	15.702	17.359	EPSD	COSMIC	14.946	Up-regulation
STE_STE20_PAKB_PAK4_ST	P35222	CTNNB1	O96013	PAK4	S37	T40P	40	Missense	distal	3	no	15.702	16.452	EPSD	COSMIC	14.946	Up-regulation
STE_STE20_PAKB_PAK4_ST	P35222	CTNNB1	O96013	PAK4	S45	T42R	42	Missense	distal	-3	no	10.130	17.271	EPSD	COSMIC	14.946	Gain
STE_STE20_PAKB_PAK4_ST	P35222	CTNNB1	O96013	PAK4	S45	T42K	42	Missense	distal	-3	no	10.130	17.255	EPSD	COSMIC	14.946	Gain
STE_STE20_PAKB_PAK4_ST	P35222	CTNNB1	O96013	PAK4	S184	A187T	187	Missense	distal	3	no	18.116	17.483	EPSD	COSMIC	14.946	Down-regulation
STE_STE20_PAKB_PAK4_ST	P35222	CTNNB1	O96013	PAK4	S184	R190C	190	Missense	distal	6	no	18.116	18.735	EPSD	COSMIC	14.946	Up-regulation
STE_STE20_PAKB_PAK4_ST	P35222	CTNNB1	O96013	PAK4	S184	A187D	187	Missense	distal	3	no	18.116	18.380	EPSD	COSMIC	14.946	Up-regulation
STE_STE20_PAKB_PAK4_ST	P35222	CTNNB1	O96013	PAK4	S184	A183S	183	Missense	proximal	-1	no	18.116	17.621	EPSD	COSMIC	14.946	Down-regulation
STE_STE20_PAKB_PAK4_ST	P35222	CTNNB1	O96013	PAK4	S184	Q177P	177	Missense	distal	-7	no	18.116	18.637	EPSD	COSMIC	14.946	Up-regulation
STE_STE20_PAKB_PAK4_ST	P35222	CTNNB1	O96013	PAK4	S184	A183T	183	Missense	proximal	-1	no	18.116	15.699	EPSD	COSMIC	14.946	Down-regulation
STE_STE20_PAKB_PAK4_ST	P35222	CTNNB1	O96013	PAK4	S184	I188M	188	Missense	distal	4	no	18.116	17.836	EPSD	COSMIC	14.946	Down-regulation
STE_STE20_PAKB_PAK4_ST	P35222	CTNNB1	O96013	PAK4	S184	R190H	190	Missense	distal	6	no	18.116	18.414	EPSD	COSMIC	14.946	Up-regulation
STE_STE20_PAKB_PAK4_ST	P35222	CTNNB1	O96013	PAK4	S184	A187V	187	Missense	distal	3	no	18.116	18.243	EPSD	COSMIC	14.946	Up-regulation
STE_STE20_PAKB_PAK4_ST	P35222	CTNNB1	O96013	PAK4	S184	E182D	182	Missense	proximal	-2	no	18.116	17.543	EPSD	COSMIC	14.946	Down-regulation
STE_STE20_PAKB_PAK4_ST	P35222	CTNNB1	O96013	PAK4	S184	R185K	185	Missense	proximal	1	no	18.116	17.809	EPSD	COSMIC	14.946	Down-regulation
STE_STE20_PAKB_PAK4_ST	P35222	CTNNB1	O96013	PAK4	S191	P192S	192	Missense	proximal	1	no	14.920	16.621	EPSD	COSMIC	14.946	Gain
STE_STE20_PAKB_PAK4_ST	P35222	CTNNB1	O96013	PAK4	S191	P192H	192	Missense	proximal	1	no	14.920	16.548	EPSD	COSMIC	14.946	Gain
STE_STE20_PAKB_PAK4_ST	P35222	CTNNB1	O96013	PAK4	S191	I188M	188	Missense	distal	-3	no	14.920	17.105	EPSD	COSMIC	14.946	Gain
STE_STE20_PAKB_PAK4_ST	P35222	CTNNB1	O96013	PAK4	S191	I198L	198	Missense	distal	7	no	14.920	15.062	EPSD	COSMIC	14.946	Gain
STE_STE20_PAKB_PAK4_ST	P35222	CTNNB1	O96013	PAK4	S552	T551K	551	Missense	proximal	-1	no	19.614	22.733	EPSD	COSMIC	14.946	Up-regulation
STE_STE20_PAKB_PAK4_ST	P35222	CTNNB1	O96013	PAK4	S552	R549C	549	Missense	distal	-3	no	19.614	12.092	EPSD	COSMIC	14.946	Loss
STE_STE20_PAKB_PAK4_ST	P35222	CTNNB1	O96013	PAK4	S552	Q545K	545	Missense	distal	-7	no	19.614	21.957	EPSD	COSMIC	14.946	Up-regulation
STE_STE20_PAKB_PAK4_ST	P35222	CTNNB1	O96013	PAK4	S552	Q558H	558	Missense	distal	6	no	19.614	19.519	EPSD	COSMIC	14.946	Down-regulation
STE_STE20_PAKB_PAK4_ST	P35222	CTNNB1	O96013	PAK4	S552	G555A	555	Missense	distal	3	no	19.614	19.689	EPSD	COSMIC	14.946	Up-regulation
STE_STE20_PAKB_PAK4_ST	P35222	CTNNB1	O96013	PAK4	S552	R550H	550	Missense	proximal	-2	no	19.614	18.324	EPSD	COSMIC	14.946	Down-regulation
STE_STE20_PAKB_PAK4_ST	P35222	CTNNB1	O96013	PAK4	S552	R550L	550	Missense	proximal	-2	no	19.614	13.421	EPSD	COSMIC	14.946	Loss
STE_STE20_PAKB_PAK4_ST	P35222	CTNNB1	O96013	PAK4	S552	D546E	546	Missense	distal	-6	no	19.614	19.657	EPSD	COSMIC	14.946	Up-regulation
STE_STE20_PAKB_PAK4_ST	P35222	CTNNB1	O96013	PAK4	S552	S552F	552	Missense	central	0	yes	19.614	0.000	EPSD	COSMIC	14.946	Loss
STE_STE20_PAKB_PAK4_ST	P35222	CTNNB1	O96013	PAK4	S552	T547S	547	Missense	distal	-5	no	19.614	19.960	EPSD	COSMIC	14.946	Up-regulation
STE_STE20_PAKB_PAK4_ST	P35222	CTNNB1	O96013	PAK4	S552	G554D	554	Missense	proximal	2	no	19.614	19.648	EPSD	COSMIC	14.946	Up-regulation
STE_STE20_PAKB_PAK4_ST	P35222	CTNNB1	O96013	PAK4	S552	R550Q	550	Missense	proximal	-2	no	19.614	14.987	EPSD	COSMIC	14.946	Down-regulation
STE_STE20_PAKB_PAK4_ST	P35222	CTNNB1	O96013	PAK4	S552	T551I	551	Missense	proximal	-1	no	19.614	20.264	EPSD	COSMIC	14.946	Up-regulation
STE_STE20_PAKB_PAK4_ST	P35222	CTNNB1	O96013	PAK4	S675	R673W	673	Missense	proximal	-2	no	29.056	23.099	PhosphoSitePlus	COSMIC	14.946	Down-regulation
STE_STE20_PAKB_PAK4_ST	P35222	CTNNB1	O96013	PAK4	S675	S680I	680	Missense	distal	5	no	29.056	28.919	PhosphoSitePlus	COSMIC	14.946	Down-regulation
STE_STE20_PAKB_PAK4_ST	P35222	CTNNB1	O96013	PAK4	S675	E677D	677	Missense	proximal	2	no	29.056	28.256	PhosphoSitePlus	COSMIC	14.946	Down-regulation
STE_STE20_PAKB_PAK4_ST	P35222	CTNNB1	O96013	PAK4	S675	R673H	673	Missense	proximal	-2	no	29.056	27.767	PhosphoSitePlus	COSMIC	14.946	Down-regulation
STE_STE20_PAKB_PAK4_ST	P35222	CTNNB1	O96013	PAK4	S675	L678F	678	Missense	distal	3	no	29.056	28.797	PhosphoSitePlus	COSMIC	14.946	Down-regulation
STE_STE20_PAKB_PAK4_ST	P35222	CTNNB1	O96013	PAK4	S675	R673C	673	Missense	proximal	-2	no	29.056	23.270	PhosphoSitePlus	COSMIC	14.946	Down-regulation
STE_STE20_PAKB_PAK4_ST	P35222	CTNNB1	O96013	PAK4	S718	S715R	715	Missense	distal	-3	no	13.303	18.632	EPSD	COSMIC	14.946	Gain
STE_STE20_PAKB_PAK4_ST	O00401	WASL	O96013	PAK4	S62	K59N	59	Missense	distal	-3	no	18.080	12.243	EPSD	COSMIC	14.946	Loss
STE_STE20_PAKB_PAK4_ST	O00401	WASL	O96013	PAK4	S479	H483Y	483	Missense	distal	4	no	18.096	18.165	EPSD	COSMIC	14.946	Up-regulation
STE_STE20_PAKB_PAK4_ST	O00401	WASL	O96013	PAK4	S484	H483Y	483	Missense	proximal	-1	no	24.018	23.699	PhosphoSitePlus;EPSD	COSMIC	14.946	Down-regulation
STE_STE20_PAKB_PAK4_ST	O00401	WASL	O96013	PAK4	S485	H483Y	483	Missense	proximal	-2	no	25.842	25.158	EPSD;PhosphoSitePlus	COSMIC	14.946	Down-regulation
STE_STE20_PAKB_PAK4_ST	P18084	ITGB5	O96013	PAK4	S149	M144V	144	Missense	distal	-5	no	16.176	15.435	EPSD	COSMIC	14.946	Down-regulation
STE_STE20_PAKB_PAK4_ST	P18084	ITGB5	O96013	PAK4	S149	M150I	150	Missense	proximal	1	no	16.176	15.841	EPSD	COSMIC	14.946	Down-regulation
STE_STE20_PAKB_PAK4_ST	P18084	ITGB5	O96013	PAK4	S181	G178R	178	Missense	distal	-3	no	14.482	20.729	EPSD	COSMIC	14.946	Gain
STE_STE20_PAKB_PAK4_ST	P18084	ITGB5	O96013	PAK4	S188	P195Q	195	Missense	distal	7	no	15.661	15.374	EPSD	COSMIC	14.946	Down-regulation
STE_STE20_PAKB_PAK4_ST	P18084	ITGB5	O96013	PAK4	S188	T193M	193	Missense	distal	5	no	15.661	15.644	EPSD	COSMIC	14.946	Down-regulation
STE_STE20_PAKB_PAK4_ST	P18084	ITGB5	O96013	PAK4	S188	P195L	195	Missense	distal	7	no	15.661	15.727	EPSD	COSMIC	14.946	Up-regulation
STE_STE20_PAKB_PAK4_ST	P18084	ITGB5	O96013	PAK4	S759	Y766C	766	Missense	distal	7	no	26.078	26.154	PhosphoSitePlus;EPSD	COSMIC	14.946	Up-regulation
STE_STE20_PAKB_PAK4_ST	P18084	ITGB5	O96013	PAK4	S762	Y766C	766	Missense	distal	4	no	23.858	24.089	EPSD;PhosphoSitePlus	COSMIC	14.946	Up-regulation
STE_STE20_PAKB_PAK4_ST	P18084	ITGB5	O96013	PAK4	S770	Y766C	766	Missense	distal	-4	no	18.652	18.057	EPSD	COSMIC	14.946	Down-regulation
STE_STE20_PAKB_PAK4_ST	P49023	PXN	O96013	PAK4	S126	V133I	133	Missense	distal	7	no	17.058	17.162	EPSD	COSMIC	14.946	Up-regulation
STE_STE20_PAKB_PAK4_ST	P49023	PXN	O96013	PAK4	S126	F120S	120	Missense	distal	-6	no	17.058	17.144	EPSD	COSMIC	14.946	Up-regulation
STE_STE20_PAKB_PAK4_ST	P49023	PXN	O96013	PAK4	S126	A127T	127	Missense	proximal	1	no	17.058	17.661	EPSD	COSMIC	14.946	Up-regulation
STE_STE20_PAKB_PAK4_ST	P49023	PXN	O96013	PAK4	S126	S126P	126	Missense	central	0	yes	17.058	0.000	EPSD	COSMIC	14.946	Loss
STE_STE20_PAKB_PAK4_ST	P49023	PXN	O96013	PAK4	S137	T136M	136	Missense	proximal	-1	no	13.269	15.286	EPSD	COSMIC	14.946	Gain
STE_STE20_PAKB_PAK4_ST	P49023	PXN	O96013	PAK4	S216	V213M	213	Missense	distal	-3	no	12.005	17.399	EPSD	COSMIC	14.946	Gain
STE_STE20_PAKB_PAK4_ST	P49023	PXN	O96013	PAK4	S272	Q279K	279	Missense	distal	7	no	23.039	22.977	PhosphoSitePlus	COSMIC	14.946	Down-regulation
STE_STE20_PAKB_PAK4_ST	P49023	PXN	O96013	PAK4	S302	G300R	300	Missense	proximal	-2	no	14.253	18.940	EPSD	COSMIC	14.946	Gain
STE_STE20_PAKB_PAK4_ST	P49023	PXN	O96013	PAK4	S302	G299S	299	Missense	distal	-3	no	14.253	15.172	EPSD	COSMIC	14.946	Gain
STE_STE20_PAKB_PAK4_ST	P49023	PXN	O96013	PAK4	S303	P304L	304	Missense	proximal	1	no	12.522	15.396	EPSD	COSMIC	14.946	Gain
STE_STE20_PAKB_PAK4_ST	P49023	PXN	O96013	PAK4	S303	G300R	300	Missense	distal	-3	no	12.522	18.770	EPSD	COSMIC	14.946	Gain
STE_STE20_PAKB_PAK4_ST	P49023	PXN	O96013	PAK4	S320	S322A	322	Missense	proximal	2	no	15.904	15.586	EPSD	COSMIC	14.946	Down-regulation
STE_STE20_PAKB_PAK4_ST	P49023	PXN	O96013	PAK4	S533	S536Y	536	Missense	distal	3	no	18.804	19.221	EPSD	COSMIC	14.946	Up-regulation
STE_STE20_PAKB_PAK4_ST	P49023	PXN	O96013	PAK4	S533	H526Y	526	Missense	distal	-7	no	18.804	18.461	EPSD	COSMIC	14.946	Down-regulation
STE_STE20_PAKB_PAK4_ST	P49023	PXN	O96013	PAK4	S533	C538R	538	Missense	distal	5	no	18.804	19.113	EPSD	COSMIC	14.946	Up-regulation
STE_STE20_PAKB_PAK4_ST	P49023	PXN	O96013	PAK4	S533	E529K	529	Missense	distal	-4	no	18.804	18.808	EPSD	COSMIC	14.946	Up-regulation
STE_STE20_PAKB_PAK4_ST	P49023	PXN	O96013	PAK4	S533	S533L	533	Missense	central	0	yes	18.804	0.000	EPSD	COSMIC	14.946	Loss
STE_STE20_PAKB_PAK4_ST	Q92974	ARHGEF2	O96013	PAK4	S107	R111Q	111	Missense	distal	4	no	15.698	15.775	EPSD	COSMIC	14.946	Up-regulation
STE_STE20_PAKB_PAK4_ST	Q92974	ARHGEF2	O96013	PAK4	S107	A104T	104	Missense	distal	-3	no	15.698	12.840	EPSD	COSMIC;CCLE	14.946	Loss
STE_STE20_PAKB_PAK4_ST	Q92974	ARHGEF2	O96013	PAK4	S107	K100M	100	Missense	distal	-7	no	15.698	13.621	EPSD	COSMIC	14.946	Loss
STE_STE20_PAKB_PAK4_ST	Q92974	ARHGEF2	O96013	PAK4	S107	R111S	111	Missense	distal	4	no	15.698	15.586	EPSD	COSMIC	14.946	Down-regulation
STE_STE20_PAKB_PAK4_ST	Q92974	ARHGEF2	O96013	PAK4	S122	Y125S	125	Missense	distal	3	no	18.495	18.078	EPSD	COSMIC	14.946	Down-regulation
STE_STE20_PAKB_PAK4_ST	Q92974	ARHGEF2	O96013	PAK4	S122	D128Y	128	Missense	distal	6	no	18.495	18.493	EPSD	COSMIC	14.946	Down-regulation
STE_STE20_PAKB_PAK4_ST	Q92974	ARHGEF2	O96013	PAK4	S122	D128E	128	Missense	distal	6	no	18.495	18.544	EPSD	COSMIC	14.946	Up-regulation
STE_STE20_PAKB_PAK4_ST	Q92974	ARHGEF2	O96013	PAK4	S122	S122L	122	Missense	central	0	yes	18.495	0.000	EPSD	COSMIC	14.946	Loss
STE_STE20_PAKB_PAK4_ST	Q92974	ARHGEF2	O96013	PAK4	S133	S137F	137	Missense	distal	4	no	16.653	17.047	EPSD	COSMIC	14.946	Up-regulation
STE_STE20_PAKB_PAK4_ST	Q92974	ARHGEF2	O96013	PAK4	S133	R131W	131	Missense	proximal	-2	no	16.653	10.696	EPSD	COSMIC;CCLE	14.946	Loss
STE_STE20_PAKB_PAK4_ST	Q92974	ARHGEF2	O96013	PAK4	S133	D128Y	128	Missense	distal	-5	no	16.653	16.979	EPSD	COSMIC	14.946	Up-regulation
STE_STE20_PAKB_PAK4_ST	Q92974	ARHGEF2	O96013	PAK4	S133	D128E	128	Missense	distal	-5	no	16.653	16.735	EPSD	COSMIC	14.946	Up-regulation
STE_STE20_PAKB_PAK4_ST	Q92974	ARHGEF2	O96013	PAK4	S133	R138S	138	Missense	distal	5	no	16.653	16.549	EPSD	COSMIC	14.946	Down-regulation
STE_STE20_PAKB_PAK4_ST	Q92974	ARHGEF2	O96013	PAK4	S142	S137F	137	Missense	distal	-5	no	17.668	17.868	EPSD	COSMIC	14.946	Up-regulation
STE_STE20_PAKB_PAK4_ST	Q92974	ARHGEF2	O96013	PAK4	S142	R138S	138	Missense	distal	-4	no	17.668	18.158	EPSD	COSMIC	14.946	Up-regulation
STE_STE20_PAKB_PAK4_ST	Q92974	ARHGEF2	O96013	PAK4	S142	R141S	141	Missense	proximal	-1	no	17.668	15.520	EPSD	COSMIC	14.946	Down-regulation
STE_STE20_PAKB_PAK4_ST	Q92974	ARHGEF2	O96013	PAK4	S142	R141C	141	Missense	proximal	-1	no	17.668	12.944	EPSD	COSMIC	14.946	Loss
STE_STE20_PAKB_PAK4_ST	Q92974	ARHGEF2	O96013	PAK4	S142	R141L	141	Missense	proximal	-1	no	17.668	14.373	EPSD	COSMIC	14.946	Loss
STE_STE20_PAKB_PAK4_ST	Q92974	ARHGEF2	O96013	PAK4	S143	S137F	137	Missense	distal	-6	no	23.198	23.113	EPSD	COSMIC	14.946	Down-regulation
STE_STE20_PAKB_PAK4_ST	Q92974	ARHGEF2	O96013	PAK4	S143	R138S	138	Missense	distal	-5	no	23.198	22.616	EPSD	COSMIC	14.946	Down-regulation
STE_STE20_PAKB_PAK4_ST	Q92974	ARHGEF2	O96013	PAK4	S143	R141S	141	Missense	proximal	-2	no	23.198	19.953	EPSD	COSMIC	14.946	Down-regulation
STE_STE20_PAKB_PAK4_ST	Q92974	ARHGEF2	O96013	PAK4	S143	R141C	141	Missense	proximal	-2	no	23.198	17.412	EPSD	COSMIC	14.946	Down-regulation
STE_STE20_PAKB_PAK4_ST	Q92974	ARHGEF2	O96013	PAK4	S143	R141L	141	Missense	proximal	-2	no	23.198	17.005	EPSD	COSMIC	14.946	Down-regulation
STE_STE20_PAKB_PAK4_ST	Q92974	ARHGEF2	O96013	PAK4	S177	T175K	175	Missense	proximal	-2	no	9.918	15.720	EPSD	COSMIC	14.946	Gain
STE_STE20_PAKB_PAK4_ST	Q92974	ARHGEF2	O96013	PAK4	S186	R183S	183	Missense	distal	-3	no	15.369	10.040	EPSD	COSMIC	14.946	Loss
STE_STE20_PAKB_PAK4_ST	Q92974	ARHGEF2	O96013	PAK4	S186	S186F	186	Missense	central	0	yes	15.369	0.000	EPSD	COSMIC	14.946	Loss
STE_STE20_PAKB_PAK4_ST	Q92974	ARHGEF2	O96013	PAK4	S645	R642C	642	Missense	distal	-3	no	19.060	11.538	EPSD	COSMIC	14.946	Loss
STE_STE20_PAKB_PAK4_ST	Q92974	ARHGEF2	O96013	PAK4	S645	S645F	645	Missense	central	0	yes	19.060	0.000	EPSD	COSMIC	14.946	Loss
STE_STE20_PAKB_PAK4_ST	Q92974	ARHGEF2	O96013	PAK4	S711	N709S	709	Missense	proximal	-2	no	13.429	15.095	EPSD	COSMIC	14.946	Gain
STE_STE20_PAKB_PAK4_ST	Q92974	ARHGEF2	O96013	PAK4	S733	P734Q	734	Missense	proximal	1	no	13.721	15.563	EPSD	COSMIC	14.946	Gain
STE_STE20_PAKB_PAK4_ST	Q92974	ARHGEF2	O96013	PAK4	S782	A780S	780	Missense	proximal	-2	no	18.870	19.072	EPSD	COSMIC	14.946	Up-regulation
STE_STE20_PAKB_PAK4_ST	Q92974	ARHGEF2	O96013	PAK4	S782	R783Q	783	Missense	proximal	1	no	18.870	18.443	EPSD	COSMIC;CCLE	14.946	Down-regulation
STE_STE20_PAKB_PAK4_ST	Q92974	ARHGEF2	O96013	PAK4	S834	E831K	831	Missense	distal	-3	no	14.354	20.306	EPSD	COSMIC	14.946	Gain
STE_STE20_PAKB_PAK4_ST	Q92974	ARHGEF2	O96013	PAK4	S886	R885W	885	Missense	proximal	-1	no	32.303	28.017	EPSD	COSMIC	14.946	Down-regulation
STE_STE20_PAKB_PAK4_ST	Q92974	ARHGEF2	O96013	PAK4	S886	R883Q	883	Missense	distal	-3	no	32.303	26.779	EPSD	COSMIC	14.946	Down-regulation
STE_STE20_PAKB_PAK4_ST	Q92974	ARHGEF2	O96013	PAK4	S886	R884C	884	Missense	proximal	-2	no	32.303	26.516	EPSD	COSMIC	14.946	Down-regulation
STE_STE20_PAKB_PAK4_ST	Q92974	ARHGEF2	O96013	PAK4	S886	R884H	884	Missense	proximal	-2	no	32.303	31.013	EPSD	COSMIC	14.946	Down-regulation
STE_STE20_PAKB_PAK4_ST	Q92974	ARHGEF2	O96013	PAK4	S886	R885C	885	Missense	proximal	-1	no	32.303	27.579	EPSD	COSMIC;CCLE	14.946	Down-regulation
STE_STE20_PAKB_PAK4_ST	Q92974	ARHGEF2	O96013	PAK4	S886	L887F	887	Missense	proximal	1	no	32.303	31.069	EPSD	COSMIC	14.946	Down-regulation
STE_STE20_PAKB_PAK4_ST	Q92974	ARHGEF2	O96013	PAK4	S886	P882L	882	Missense	distal	-4	no	32.303	29.855	EPSD	COSMIC	14.946	Down-regulation
STE_STE20_PAKB_PAK4_ST	Q92974	ARHGEF2	O96013	PAK4	S886	P888S	888	Missense	proximal	2	no	32.303	32.899	EPSD	COSMIC	14.946	Up-regulation
STE_STE20_PAKB_PAK4_ST	Q92974	ARHGEF2	O96013	PAK4	S886	P888L	888	Missense	proximal	2	no	32.303	30.505	EPSD	COSMIC	14.946	Down-regulation
STE_STE20_PAKB_PAK4_ST	P62826	RAN	O96013	PAK4	S135	A133V	133	Missense	proximal	-2	no	27.598	24.971	PhosphoSitePlus	COSMIC	14.946	Down-regulation
STE_STE20_PAKB_PAK4_ST	P62826	RAN	O96013	PAK4	S135	K132N	132	Missense	distal	-3	no	27.598	21.761	PhosphoSitePlus	COSMIC	14.946	Down-regulation
STE_STE20_PAKB_PAK4_ST	P62826	RAN	O96013	PAK4	S153	N156S	156	Missense	distal	3	no	15.422	15.131	EPSD	COSMIC;GDSC;CCLE	14.946	Down-regulation
STE_STE20_PAKB_PAK4_ST	P62826	RAN	O96013	PAK4	S153	A151T	151	Missense	proximal	-2	no	15.422	13.133	EPSD	COSMIC	14.946	Loss
STE_STE20_PAKB_PAK4_ST	P04637	TP53	O96013	PAK4	S20	E17K	17	Missense	distal	-3	no	10.673	16.625	EPSD	COSMIC	14.946	Gain
STE_STE20_PAKB_PAK4_ST	P04637	TP53	O96013	PAK4	S20	T18K	18	Missense	proximal	-2	no	10.673	16.475	EPSD	COSMIC	14.946	Gain
STE_STE20_PAKB_PAK4_ST	P04637	TP53	O96013	PAK4	S20	T18R	18	Missense	proximal	-2	no	10.673	16.409	EPSD	COSMIC	14.946	Gain
STE_STE20_PAKB_PAK4_ST	P04637	TP53	O96013	PAK4	S46	M40I	40	Missense	distal	-6	no	16.273	16.127	EPSD	COSMIC	14.946	Down-regulation
STE_STE20_PAKB_PAK4_ST	P04637	TP53	O96013	PAK4	S46	W53C	53	Missense	distal	7	no	16.273	16.321	EPSD	COSMIC	14.946	Up-regulation
STE_STE20_PAKB_PAK4_ST	P04637	TP53	O96013	PAK4	S46	W53G	53	Missense	distal	7	no	16.273	16.237	EPSD	COSMIC	14.946	Down-regulation
STE_STE20_PAKB_PAK4_ST	P04637	TP53	O96013	PAK4	S46	S46F	46	Missense	central	0	yes	16.273	0.000	EPSD	COSMIC	14.946	Loss
STE_STE20_PAKB_PAK4_ST	P04637	TP53	O96013	PAK4	S46	D49Y	49	Missense	distal	3	no	16.273	15.568	EPSD	COSMIC	14.946	Down-regulation
STE_STE20_PAKB_PAK4_ST	P04637	TP53	O96013	PAK4	S46	P47L	47	Missense	proximal	1	no	16.273	19.146	EPSD	COSMIC	14.946	Up-regulation
STE_STE20_PAKB_PAK4_ST	P04637	TP53	O96013	PAK4	S46	D49H	49	Missense	distal	3	no	16.273	15.726	EPSD	COSMIC;GDSC;CCLE	14.946	Down-regulation
STE_STE20_PAKB_PAK4_ST	P04637	TP53	O96013	PAK4	S46	P47S	47	Missense	proximal	1	no	16.273	17.974	EPSD	COSMIC	14.946	Up-regulation
STE_STE20_PAKB_PAK4_ST	P04637	TP53	O96013	PAK4	S46	D41N	41	Missense	distal	-5	no	16.273	16.327	EPSD	COSMIC	14.946	Up-regulation
STE_STE20_PAKB_PAK4_ST	P04637	TP53	O96013	PAK4	S46	D48H	48	Missense	proximal	2	no	16.273	16.314	EPSD	COSMIC	14.946	Up-regulation
STE_STE20_PAKB_PAK4_ST	P04637	TP53	O96013	PAK4	S46	D49N	49	Missense	distal	3	no	16.273	15.443	EPSD	COSMIC	14.946	Down-regulation
STE_STE20_PAKB_PAK4_ST	P04637	TP53	O96013	PAK4	S46	M44I	44	Missense	proximal	-2	no	16.273	14.511	EPSD	COSMIC	14.946	Loss
STE_STE20_PAKB_PAK4_ST	P04637	TP53	O96013	PAK4	S46	Q52H	52	Missense	distal	6	no	16.273	16.178	EPSD	COSMIC	14.946	Down-regulation
STE_STE20_PAKB_PAK4_ST	P04637	TP53	O96013	PAK4	S46	D49V	49	Missense	distal	3	no	16.273	16.136	EPSD	COSMIC	14.946	Down-regulation
STE_STE20_PAKB_PAK4_ST	P04637	TP53	O96013	PAK4	S46	A39V	39	Missense	distal	-7	no	16.273	13.720	EPSD	COSMIC	14.946	Loss
STE_STE20_PAKB_PAK4_ST	P04637	TP53	O96013	PAK4	S46	A39S	39	Missense	distal	-7	no	16.273	15.632	EPSD	COSMIC	14.946	Down-regulation
STE_STE20_PAKB_PAK4_ST	P04637	TP53	O96013	PAK4	S46	D42Y	42	Missense	distal	-4	no	16.273	15.748	EPSD	COSMIC	14.946	Down-regulation
STE_STE20_PAKB_PAK4_ST	P04637	TP53	O96013	PAK4	S46	M44R	44	Missense	proximal	-2	no	16.273	18.412	EPSD	COSMIC	14.946	Up-regulation
STE_STE20_PAKB_PAK4_ST	P04637	TP53	O96013	PAK4	S46	S46P	46	Missense	central	0	yes	16.273	0.000	EPSD	COSMIC	14.946	Loss
STE_STE20_PAKB_PAK4_ST	P04637	TP53	O96013	PAK4	S46	M44V	44	Missense	proximal	-2	no	16.273	12.338	EPSD	COSMIC	14.946	Loss
STE_STE20_PAKB_PAK4_ST	P04637	TP53	O96013	PAK4	S46	L45P	45	Missense	proximal	-1	no	16.273	15.160	EPSD	COSMIC	14.946	Down-regulation
STE_STE20_PAKB_PAK4_ST	P04637	TP53	O96013	PAK4	S46	M44T	44	Missense	proximal	-2	no	16.273	12.676	EPSD	COSMIC	14.946	Loss
STE_STE20_PAKB_PAK4_ST	P04637	TP53	O96013	PAK4	S46	A39T	39	Missense	distal	-7	no	16.273	14.959	EPSD	COSMIC	14.946	Down-regulation
STE_STE20_PAKB_PAK4_ST	P04637	TP53	O96013	PAK4	S46	L43F	43	Missense	distal	-3	no	16.273	17.607	EPSD	COSMIC	14.946	Up-regulation
STE_STE20_PAKB_PAK4_ST	P04637	TP53	O96013	PAK4	S46	D41H	41	Missense	distal	-5	no	16.273	16.505	EPSD	COSMIC	14.946	Up-regulation
STE_STE20_PAKB_PAK4_ST	P04637	TP53	O96013	PAK4	S46	D49E	49	Missense	distal	3	no	16.273	15.537	EPSD	COSMIC	14.946	Down-regulation
STE_STE20_PAKB_PAK4_ST	P04637	TP53	O96013	PAK4	S46	D49G	49	Missense	distal	3	no	16.273	15.934	EPSD	COSMIC	14.946	Down-regulation
STE_STE20_PAKB_PAK4_ST	P04637	TP53	O96013	PAK4	S46	D48A	48	Missense	proximal	2	no	16.273	16.861	EPSD	COSMIC	14.946	Up-regulation
STE_STE20_PAKB_PAK4_ST	P04637	TP53	O96013	PAK4	S46	D48Y	48	Missense	proximal	2	no	16.273	16.135	EPSD	COSMIC	14.946	Down-regulation
STE_STE20_PAKB_PAK4_ST	P04637	TP53	O96013	PAK4	S46	D48E	48	Missense	proximal	2	no	16.273	17.073	EPSD	COSMIC	14.946	Up-regulation
STE_STE20_PAKB_PAK4_ST	P04637	TP53	O96013	PAK4	S46	D49I	49	Missense	distal	3	no	16.273	15.799	EPSD	COSMIC	14.946	Down-regulation
STE_STE20_PAKB_PAK4_ST	P04637	TP53	O96013	PAK4	S46	D41E	41	Missense	distal	-5	no	16.273	16.354	EPSD	COSMIC	14.946	Up-regulation
STE_STE20_PAKB_PAK4_ST	P04637	TP53	O96013	PAK4	S106	Q104H	104	Missense	proximal	-2	no	13.479	16.817	EPSD	COSMIC	14.946	Gain
STE_STE20_PAKB_PAK4_ST	P04637	TP53	O96013	PAK4	S149	W146R	146	Missense	distal	-3	no	9.193	16.118	EPSD	COSMIC	14.946	Gain
STE_STE20_PAKB_PAK4_ST	P04637	TP53	O96013	PAK4	S183	G187V	187	Missense	distal	4	no	14.982	15.190	EPSD	COSMIC	14.946	Up-regulation
STE_STE20_PAKB_PAK4_ST	P04637	TP53	O96013	PAK4	S183	G187D	187	Missense	distal	4	no	14.982	15.055	EPSD	COSMIC	14.946	Up-regulation
STE_STE20_PAKB_PAK4_ST	P04637	TP53	O96013	PAK4	S183	G187A	187	Missense	distal	4	no	14.982	15.026	EPSD	COSMIC	14.946	Up-regulation
STE_STE20_PAKB_PAK4_ST	P04637	TP53	O96013	PAK4	S183	S183C	183	Missense	central	0	yes	14.982	0.000	EPSD	COSMIC	14.946	Loss
STE_STE20_PAKB_PAK4_ST	P04637	TP53	O96013	PAK4	S183	S183P	183	Missense	central	0	yes	14.982	0.000	EPSD	COSMIC	14.946	Loss
STE_STE20_PAKB_PAK4_ST	P04637	TP53	O96013	PAK4	S183	S185G	185	Missense	proximal	2	no	14.982	14.041	EPSD	COSMIC	14.946	Loss
STE_STE20_PAKB_PAK4_ST	P04637	TP53	O96013	PAK4	S183	P190N	190	Missense	distal	7	no	14.982	14.840	EPSD	COSMIC	14.946	Loss
STE_STE20_PAKB_PAK4_ST	P04637	TP53	O96013	PAK4	S183	D184N	184	Missense	proximal	1	no	14.982	16.464	EPSD	COSMIC	14.946	Up-regulation
STE_STE20_PAKB_PAK4_ST	P04637	TP53	O96013	PAK4	S183	S185R	185	Missense	proximal	2	no	14.982	13.863	EPSD	COSMIC	14.946	Loss
STE_STE20_PAKB_PAK4_ST	P04637	TP53	O96013	PAK4	S183	S183L	183	Missense	central	0	yes	14.982	0.000	EPSD	COSMIC	14.946	Loss
STE_STE20_PAKB_PAK4_ST	P04637	TP53	O96013	PAK4	S183	R181L	181	Missense	proximal	-2	no	14.982	8.789	EPSD	COSMIC	14.946	Loss
STE_STE20_PAKB_PAK4_ST	P04637	TP53	O96013	PAK4	S183	H178P	178	Missense	distal	-5	no	14.982	14.644	EPSD	COSMIC	14.946	Loss
STE_STE20_PAKB_PAK4_ST	P04637	TP53	O96013	PAK4	S183	D186N	186	Missense	distal	3	no	14.982	14.151	EPSD	COSMIC	14.946	Loss
STE_STE20_PAKB_PAK4_ST	P04637	TP53	O96013	PAK4	S183	A189S	189	Missense	distal	6	no	14.982	14.971	EPSD	COSMIC	14.946	Down-regulation
STE_STE20_PAKB_PAK4_ST	P04637	TP53	O96013	PAK4	S183	H178L	178	Missense	distal	-5	no	14.982	14.475	EPSD	COSMIC	14.946	Loss
STE_STE20_PAKB_PAK4_ST	P04637	TP53	O96013	PAK4	S183	D184Y	184	Missense	proximal	1	no	14.982	16.011	EPSD	COSMIC	14.946	Up-regulation
STE_STE20_PAKB_PAK4_ST	P04637	TP53	O96013	PAK4	S183	L188V	188	Missense	distal	5	no	14.982	15.116	EPSD	COSMIC	14.946	Up-regulation
STE_STE20_PAKB_PAK4_ST	P04637	TP53	O96013	PAK4	S183	A189V	189	Missense	distal	6	no	14.982	15.147	EPSD	COSMIC	14.946	Up-regulation
STE_STE20_PAKB_PAK4_ST	P04637	TP53	O96013	PAK4	S183	H178Y	178	Missense	distal	-5	no	14.982	15.076	EPSD	COSMIC	14.946	Up-regulation
STE_STE20_PAKB_PAK4_ST	P04637	TP53	O96013	PAK4	S183	D186E	186	Missense	distal	3	no	14.982	14.245	EPSD	COSMIC	14.946	Loss
STE_STE20_PAKB_PAK4_ST	P04637	TP53	O96013	PAK4	S183	C182Y	182	Missense	proximal	-1	no	14.982	17.007	EPSD	COSMIC	14.946	Up-regulation
STE_STE20_PAKB_PAK4_ST	P04637	TP53	O96013	PAK4	S183	D186H	186	Missense	distal	3	no	14.982	14.434	EPSD	COSMIC	14.946	Loss
STE_STE20_PAKB_PAK4_ST	P04637	TP53	O96013	PAK4	S183	L188Q	188	Missense	distal	5	no	14.982	15.249	EPSD	COSMIC	14.946	Up-regulation
STE_STE20_PAKB_PAK4_ST	P04637	TP53	O96013	PAK4	S183	H178N	178	Missense	distal	-5	no	14.982	14.804	EPSD	COSMIC	14.946	Loss
STE_STE20_PAKB_PAK4_ST	P04637	TP53	O96013	PAK4	S183	G187R	187	Missense	distal	4	no	14.982	14.908	EPSD	COSMIC;GDSC	14.946	Loss
STE_STE20_PAKB_PAK4_ST	P04637	TP53	O96013	PAK4	S183	C182S	182	Missense	proximal	-1	no	14.982	17.559	EPSD	COSMIC	14.946	Up-regulation
STE_STE20_PAKB_PAK4_ST	P04637	TP53	O96013	PAK4	S183	P190F	190	Missense	distal	7	no	14.982	14.950	EPSD	COSMIC	14.946	Down-regulation
STE_STE20_PAKB_PAK4_ST	P04637	TP53	O96013	PAK4	S183	G187C	187	Missense	distal	4	no	14.982	15.241	EPSD	COSMIC	14.946	Up-regulation
STE_STE20_PAKB_PAK4_ST	P04637	TP53	O96013	PAK4	S183	S185T	185	Missense	proximal	2	no	14.982	14.110	EPSD	COSMIC	14.946	Loss
STE_STE20_PAKB_PAK4_ST	P04637	TP53	O96013	PAK4	S183	P190H	190	Missense	distal	7	no	14.982	14.747	EPSD	COSMIC	14.946	Loss
STE_STE20_PAKB_PAK4_ST	P04637	TP53	O96013	PAK4	S183	S185N	185	Missense	proximal	2	no	14.982	14.234	EPSD	COSMIC	14.946	Loss
STE_STE20_PAKB_PAK4_ST	P04637	TP53	O96013	PAK4	S183	D186G	186	Missense	distal	3	no	14.982	14.642	EPSD	COSMIC	14.946	Loss
STE_STE20_PAKB_PAK4_ST	P04637	TP53	O96013	PAK4	S183	D186V	186	Missense	distal	3	no	14.982	14.844	EPSD	COSMIC	14.946	Loss
STE_STE20_PAKB_PAK4_ST	P04637	TP53	O96013	PAK4	S183	P177I	177	Missense	distal	-6	no	14.982	14.949	EPSD	COSMIC	14.946	Down-regulation
STE_STE20_PAKB_PAK4_ST	P04637	TP53	O96013	PAK4	S183	P190A	190	Missense	distal	7	no	14.982	14.790	EPSD	COSMIC	14.946	Loss
STE_STE20_PAKB_PAK4_ST	P04637	TP53	O96013	PAK4	S183	S185C	185	Missense	proximal	2	no	14.982	13.895	EPSD	COSMIC	14.946	Loss
STE_STE20_PAKB_PAK4_ST	P04637	TP53	O96013	PAK4	S183	S185I	185	Missense	proximal	2	no	14.982	13.618	EPSD	COSMIC	14.946	Loss
STE_STE20_PAKB_PAK4_ST	P04637	TP53	O96013	PAK4	S183	A189P	189	Missense	distal	6	no	14.982	15.165	EPSD	COSMIC	14.946	Up-regulation
STE_STE20_PAKB_PAK4_ST	P04637	TP53	O96013	PAK4	S183	E180Q	180	Missense	distal	-3	no	14.982	15.425	EPSD	COSMIC	14.946	Up-regulation
STE_STE20_PAKB_PAK4_ST	P04637	TP53	O96013	PAK4	S183	R181S	181	Missense	proximal	-2	no	14.982	11.737	EPSD	COSMIC	14.946	Loss
STE_STE20_PAKB_PAK4_ST	P04637	TP53	O96013	PAK4	S183	C182R	182	Missense	proximal	-1	no	14.982	19.706	EPSD	COSMIC	14.946	Up-regulation
STE_STE20_PAKB_PAK4_ST	P04637	TP53	O96013	PAK4	S183	E180G	180	Missense	distal	-3	no	14.982	14.702	EPSD	COSMIC	14.946	Loss
STE_STE20_PAKB_PAK4_ST	P04637	TP53	O96013	PAK4	S183	L188M	188	Missense	distal	5	no	14.982	15.276	EPSD	COSMIC	14.946	Up-regulation
STE_STE20_PAKB_PAK4_ST	P04637	TP53	O96013	PAK4	S183	P177F	177	Missense	distal	-6	no	14.982	15.005	EPSD	COSMIC	14.946	Up-regulation
STE_STE20_PAKB_PAK4_ST	P04637	TP53	O96013	PAK4	S183	D184E	184	Missense	proximal	1	no	14.982	15.111	EPSD	COSMIC	14.946	Up-regulation
STE_STE20_PAKB_PAK4_ST	P04637	TP53	O96013	PAK4	S183	A189G	189	Missense	distal	6	no	14.982	15.143	EPSD	COSMIC	14.946	Up-regulation
STE_STE20_PAKB_PAK4_ST	P04637	TP53	O96013	PAK4	S183	R181G	181	Missense	proximal	-2	no	14.982	10.294	EPSD	COSMIC	14.946	Loss
STE_STE20_PAKB_PAK4_ST	P04637	TP53	O96013	PAK4	S183	D186X	186	Missense	distal	3	no	14.982	14.434	EPSD	COSMIC	14.946	Loss
STE_STE20_PAKB_PAK4_ST	P04637	TP53	O96013	PAK4	S183	R181Y	181	Missense	proximal	-2	no	14.982	13.008	EPSD	COSMIC	14.946	Loss
STE_STE20_PAKB_PAK4_ST	P04637	TP53	O96013	PAK4	S183	D184G	184	Missense	proximal	1	no	14.982	15.167	EPSD	COSMIC	14.946	Up-regulation
STE_STE20_PAKB_PAK4_ST	P04637	TP53	O96013	PAK4	S215	R209Q	209	Missense	distal	-6	no	24.434	24.255	PhosphoSitePlus	COSMIC	14.946	Down-regulation
STE_STE20_PAKB_PAK4_ST	P04637	TP53	O96013	PAK4	S215	R209W	209	Missense	distal	-6	no	24.434	24.140	PhosphoSitePlus	COSMIC	14.946	Down-regulation
STE_STE20_PAKB_PAK4_ST	P04637	TP53	O96013	PAK4	S215	R209P	209	Missense	distal	-6	no	24.434	24.215	PhosphoSitePlus	COSMIC	14.946	Down-regulation
STE_STE20_PAKB_PAK4_ST	P04637	TP53	O96013	PAK4	S215	R209L	209	Missense	distal	-6	no	24.434	24.081	PhosphoSitePlus	COSMIC	14.946	Down-regulation
STE_STE20_PAKB_PAK4_ST	P04637	TP53	O96013	PAK4	S215	R209G	209	Missense	distal	-6	no	24.434	24.165	PhosphoSitePlus	COSMIC	14.946	Down-regulation
STE_STE20_PAKB_PAK4_ST	P04637	TP53	O96013	PAK4	S215	R209C	209	Missense	distal	-6	no	24.434	24.083	PhosphoSitePlus	COSMIC	14.946	Down-regulation
STE_STE20_PAKB_PAK4_ST	P04637	TP53	O96013	PAK4	S215	V216A	216	Missense	proximal	1	no	24.434	24.180	PhosphoSitePlus	COSMIC	14.946	Down-regulation
STE_STE20_PAKB_PAK4_ST	P04637	TP53	O96013	PAK4	S215	V217A	217	Missense	proximal	2	no	24.434	24.942	PhosphoSitePlus	COSMIC	14.946	Up-regulation
STE_STE20_PAKB_PAK4_ST	P04637	TP53	O96013	PAK4	S215	P222S	222	Missense	distal	7	no	24.434	24.129	PhosphoSitePlus	COSMIC	14.946	Down-regulation
STE_STE20_PAKB_PAK4_ST	P04637	TP53	O96013	PAK4	S215	P219L	219	Missense	distal	4	no	24.434	25.132	PhosphoSitePlus	COSMIC	14.946	Up-regulation
STE_STE20_PAKB_PAK4_ST	P04637	TP53	O96013	PAK4	S215	V218M	218	Missense	distal	3	no	24.434	23.801	PhosphoSitePlus	COSMIC	14.946	Down-regulation
STE_STE20_PAKB_PAK4_ST	P04637	TP53	O96013	PAK4	S215	D208E	208	Missense	distal	-7	no	24.434	24.669	PhosphoSitePlus	COSMIC	14.946	Up-regulation
STE_STE20_PAKB_PAK4_ST	P04637	TP53	O96013	PAK4	S215	F212L	212	Missense	distal	-3	no	24.434	23.100	PhosphoSitePlus	COSMIC	14.946	Down-regulation
STE_STE20_PAKB_PAK4_ST	P04637	TP53	O96013	PAK4	S215	H214Q	214	Missense	proximal	-1	no	24.434	23.473	PhosphoSitePlus	COSMIC	14.946	Down-regulation
STE_STE20_PAKB_PAK4_ST	P04637	TP53	O96013	PAK4	S215	P219H	219	Missense	distal	4	no	24.434	24.495	PhosphoSitePlus	COSMIC	14.946	Up-regulation
STE_STE20_PAKB_PAK4_ST	P04637	TP53	O96013	PAK4	S215	R213W	213	Missense	proximal	-2	no	24.434	18.477	PhosphoSitePlus	COSMIC	14.946	Down-regulation
STE_STE20_PAKB_PAK4_ST	P04637	TP53	O96013	PAK4	S215	N210D	210	Missense	distal	-5	no	24.434	24.380	PhosphoSitePlus	COSMIC	14.946	Down-regulation
STE_STE20_PAKB_PAK4_ST	P04637	TP53	O96013	PAK4	S215	V218A	218	Missense	distal	3	no	24.434	24.308	PhosphoSitePlus	COSMIC	14.946	Down-regulation
STE_STE20_PAKB_PAK4_ST	P04637	TP53	O96013	PAK4	S215	S215C	215	Missense	central	0	yes	24.434	0.000	PhosphoSitePlus	COSMIC;GDSC;CCLE	14.946	Loss
STE_STE20_PAKB_PAK4_ST	P04637	TP53	O96013	PAK4	S215	V218L	218	Missense	distal	3	no	24.434	24.969	PhosphoSitePlus	COSMIC;GDSC;CCLE	14.946	Up-regulation
STE_STE20_PAKB_PAK4_ST	P04637	TP53	O96013	PAK4	S215	T211N	211	Missense	distal	-4	no	24.434	24.182	PhosphoSitePlus	COSMIC	14.946	Down-regulation
STE_STE20_PAKB_PAK4_ST	P04637	TP53	O96013	PAK4	S215	N210S	210	Missense	distal	-5	no	24.434	24.516	PhosphoSitePlus	COSMIC	14.946	Up-regulation
STE_STE20_PAKB_PAK4_ST	P04637	TP53	O96013	PAK4	S215	P222T	222	Missense	distal	7	no	24.434	24.213	PhosphoSitePlus	COSMIC	14.946	Down-regulation
STE_STE20_PAKB_PAK4_ST	P04637	TP53	O96013	PAK4	S215	F212I	212	Missense	distal	-3	no	24.434	22.859	PhosphoSitePlus	COSMIC	14.946	Down-regulation
STE_STE20_PAKB_PAK4_ST	P04637	TP53	O96013	PAK4	S215	N210H	210	Missense	distal	-5	no	24.434	24.612	PhosphoSitePlus	COSMIC	14.946	Up-regulation
STE_STE20_PAKB_PAK4_ST	P04637	TP53	O96013	PAK4	S215	E221G	221	Missense	distal	6	no	24.434	24.451	PhosphoSitePlus	COSMIC	14.946	Up-regulation
STE_STE20_PAKB_PAK4_ST	P04637	TP53	O96013	PAK4	S215	E221D	221	Missense	distal	6	no	24.434	24.385	PhosphoSitePlus	COSMIC	14.946	Down-regulation
STE_STE20_PAKB_PAK4_ST	P04637	TP53	O96013	PAK4	S215	V217E	217	Missense	proximal	2	no	24.434	25.154	PhosphoSitePlus	COSMIC	14.946	Up-regulation
STE_STE20_PAKB_PAK4_ST	P04637	TP53	O96013	PAK4	S215	R209T	209	Missense	distal	-6	no	24.434	24.189	PhosphoSitePlus	COSMIC	14.946	Down-regulation
STE_STE20_PAKB_PAK4_ST	P04637	TP53	O96013	PAK4	S215	P222L	222	Missense	distal	7	no	24.434	24.500	PhosphoSitePlus	COSMIC	14.946	Up-regulation
STE_STE20_PAKB_PAK4_ST	P04637	TP53	O96013	PAK4	S215	P219R	219	Missense	distal	4	no	24.434	24.460	PhosphoSitePlus	COSMIC	14.946	Up-regulation
STE_STE20_PAKB_PAK4_ST	P04637	TP53	O96013	PAK4	S215	P219S	219	Missense	distal	4	no	24.434	24.348	PhosphoSitePlus	COSMIC	14.946	Down-regulation
STE_STE20_PAKB_PAK4_ST	P04637	TP53	O96013	PAK4	S215	D208Y	208	Missense	distal	-7	no	24.434	23.450	PhosphoSitePlus	COSMIC	14.946	Down-regulation
STE_STE20_PAKB_PAK4_ST	P04637	TP53	O96013	PAK4	S215	P222Q	222	Missense	distal	7	no	24.434	24.147	PhosphoSitePlus	COSMIC	14.946	Down-regulation
STE_STE20_PAKB_PAK4_ST	P04637	TP53	O96013	PAK4	S215	P222A	222	Missense	distal	7	no	24.434	24.243	PhosphoSitePlus	COSMIC	14.946	Down-regulation
STE_STE20_PAKB_PAK4_ST	P04637	TP53	O96013	PAK4	S215	V217L	217	Missense	proximal	2	no	24.434	22.866	PhosphoSitePlus	COSMIC	14.946	Down-regulation
STE_STE20_PAKB_PAK4_ST	P04637	TP53	O96013	PAK4	S215	T211S	211	Missense	distal	-4	no	24.434	25.681	PhosphoSitePlus	COSMIC	14.946	Up-regulation
STE_STE20_PAKB_PAK4_ST	P04637	TP53	O96013	PAK4	S215	D208H	208	Missense	distal	-7	no	24.434	23.794	PhosphoSitePlus	COSMIC	14.946	Down-regulation
STE_STE20_PAKB_PAK4_ST	P04637	TP53	O96013	PAK4	S215	V217M	217	Missense	proximal	2	no	24.434	24.155	PhosphoSitePlus	COSMIC	14.946	Down-regulation
STE_STE20_PAKB_PAK4_ST	P04637	TP53	O96013	PAK4	S215	N210T	210	Missense	distal	-5	no	24.434	24.169	PhosphoSitePlus	COSMIC	14.946	Down-regulation
STE_STE20_PAKB_PAK4_ST	P04637	TP53	O96013	PAK4	S215	N210K	210	Missense	distal	-5	no	24.434	25.010	PhosphoSitePlus	COSMIC	14.946	Up-regulation
STE_STE20_PAKB_PAK4_ST	P04637	TP53	O96013	PAK4	S215	F212S	212	Missense	distal	-3	no	24.434	22.384	PhosphoSitePlus	COSMIC	14.946	Down-regulation
STE_STE20_PAKB_PAK4_ST	P04637	TP53	O96013	PAK4	S215	H214P	214	Missense	proximal	-1	no	24.434	22.406	PhosphoSitePlus	COSMIC	14.946	Down-regulation
STE_STE20_PAKB_PAK4_ST	P04637	TP53	O96013	PAK4	S215	D208I	208	Missense	distal	-7	no	24.434	23.085	PhosphoSitePlus	COSMIC	14.946	Down-regulation
STE_STE20_PAKB_PAK4_ST	P04637	TP53	O96013	PAK4	S215	P219C	219	Missense	distal	4	no	24.434	24.794	PhosphoSitePlus	COSMIC	14.946	Up-regulation
STE_STE20_PAKB_PAK4_ST	P04637	TP53	O96013	PAK4	S215	F212Y	212	Missense	distal	-3	no	24.434	23.829	PhosphoSitePlus	COSMIC	14.946	Down-regulation
STE_STE20_PAKB_PAK4_ST	P04637	TP53	O96013	PAK4	S215	Y220L	220	Missense	distal	5	no	24.434	24.266	PhosphoSitePlus	COSMIC	14.946	Down-regulation
STE_STE20_PAKB_PAK4_ST	P04637	TP53	O96013	PAK4	S215	Y220X	220	Missense	distal	5	no	24.434	24.480	PhosphoSitePlus	COSMIC	14.946	Up-regulation
STE_STE20_PAKB_PAK4_ST	P04637	TP53	O96013	PAK4	S215	H214A	214	Missense	proximal	-1	no	24.434	25.161	PhosphoSitePlus	COSMIC	14.946	Up-regulation
STE_STE20_PAKB_PAK4_ST	P04637	TP53	O96013	PAK4	S269	G266K	266	Missense	distal	-3	no	10.413	16.645	EPSD	COSMIC	14.946	Gain
STE_STE20_PAKB_PAK4_ST	P04637	TP53	O96013	PAK4	S314	N311K	311	Missense	distal	-3	no	9.661	15.498	EPSD	COSMIC	14.946	Gain
STE_STE20_PAKB_PAK4_ST	P04637	TP53	O96013	PAK4	S362	G361R	361	Missense	proximal	-1	no	11.507	15.453	EPSD	COSMIC	14.946	Gain
STE_STE20_PAKB_PAK4_ST	P04637	TP53	O96013	PAK4	S366	S367F	367	Missense	proximal	1	no	16.494	16.433	EPSD	COSMIC	14.946	Down-regulation
STE_STE20_PAKB_PAK4_ST	P04637	TP53	O96013	PAK4	S366	K370N	370	Missense	distal	4	no	16.494	16.669	EPSD	COSMIC	14.946	Up-regulation
STE_STE20_PAKB_PAK4_ST	P04637	TP53	O96013	PAK4	S366	G361E	361	Missense	distal	-5	no	16.494	16.726	EPSD	COSMIC	14.946	Up-regulation
STE_STE20_PAKB_PAK4_ST	P04637	TP53	O96013	PAK4	S366	P359S	359	Missense	distal	-7	no	16.494	16.106	EPSD	COSMIC	14.946	Down-regulation
STE_STE20_PAKB_PAK4_ST	P04637	TP53	O96013	PAK4	S366	A364D	364	Missense	proximal	-2	no	16.494	15.120	EPSD	COSMIC	14.946	Down-regulation
STE_STE20_PAKB_PAK4_ST	P04637	TP53	O96013	PAK4	S366	H365Y	365	Missense	proximal	-1	no	16.494	16.175	EPSD	COSMIC	14.946	Down-regulation
STE_STE20_PAKB_PAK4_ST	P04637	TP53	O96013	PAK4	S366	G360A	360	Missense	distal	-6	no	16.494	16.659	EPSD	COSMIC	14.946	Up-regulation
STE_STE20_PAKB_PAK4_ST	P04637	TP53	O96013	PAK4	S366	A364T	364	Missense	proximal	-2	no	16.494	14.205	EPSD	COSMIC	14.946	Loss
STE_STE20_PAKB_PAK4_ST	P04637	TP53	O96013	PAK4	S366	S366A	366	Missense	central	0	yes	16.494	0.000	EPSD	COSMIC	14.946	Loss
STE_STE20_PAKB_PAK4_ST	P04637	TP53	O96013	PAK4	S366	G361R	361	Missense	distal	-5	no	16.494	17.363	EPSD	COSMIC	14.946	Up-regulation
STE_STE20_PAKB_PAK4_ST	P04637	TP53	O96013	PAK4	S366	K370Q	370	Missense	distal	4	no	16.494	16.500	EPSD	COSMIC	14.946	Up-regulation
STE_STE20_PAKB_PAK4_ST	P04637	TP53	O96013	PAK4	S366	K373R	373	Missense	distal	7	no	16.494	16.520	EPSD	COSMIC	14.946	Up-regulation
STE_STE20_PAKB_PAK4_ST	P04637	TP53	O96013	PAK4	S366	S371P	371	Missense	distal	5	no	16.494	16.482	EPSD	COSMIC	14.946	Down-regulation
STE_STE20_PAKB_PAK4_ST	P04637	TP53	O96013	PAK4	S371	S367F	367	Missense	distal	-4	no	21.189	19.579	EPSD	COSMIC	14.946	Down-regulation
STE_STE20_PAKB_PAK4_ST	P04637	TP53	O96013	PAK4	S371	K370N	370	Missense	proximal	-1	no	21.189	18.766	EPSD	COSMIC	14.946	Down-regulation
STE_STE20_PAKB_PAK4_ST	P04637	TP53	O96013	PAK4	S371	A364D	364	Missense	distal	-7	no	21.189	20.587	EPSD	COSMIC	14.946	Down-regulation
STE_STE20_PAKB_PAK4_ST	P04637	TP53	O96013	PAK4	S371	H365Y	365	Missense	distal	-6	no	21.189	21.204	EPSD	COSMIC	14.946	Up-regulation
STE_STE20_PAKB_PAK4_ST	P04637	TP53	O96013	PAK4	S371	A364T	364	Missense	distal	-7	no	21.189	19.875	EPSD	COSMIC	14.946	Down-regulation
STE_STE20_PAKB_PAK4_ST	P04637	TP53	O96013	PAK4	S371	S376T	376	Missense	distal	5	no	21.189	21.229	EPSD	COSMIC	14.946	Up-regulation
STE_STE20_PAKB_PAK4_ST	P04637	TP53	O96013	PAK4	S371	S366A	366	Missense	distal	-5	no	21.189	21.177	EPSD	COSMIC	14.946	Down-regulation
STE_STE20_PAKB_PAK4_ST	P04637	TP53	O96013	PAK4	S371	T377I	377	Missense	distal	6	no	21.189	21.384	EPSD	COSMIC	14.946	Up-regulation
STE_STE20_PAKB_PAK4_ST	P04637	TP53	O96013	PAK4	S371	S378F	378	Missense	distal	7	no	21.189	21.463	EPSD	COSMIC	14.946	Up-regulation
STE_STE20_PAKB_PAK4_ST	P04637	TP53	O96013	PAK4	S371	K370Q	370	Missense	proximal	-1	no	21.189	18.798	EPSD	COSMIC	14.946	Down-regulation
STE_STE20_PAKB_PAK4_ST	P04637	TP53	O96013	PAK4	S371	K373R	373	Missense	proximal	2	no	21.189	21.030	EPSD	COSMIC	14.946	Down-regulation
STE_STE20_PAKB_PAK4_ST	P04637	TP53	O96013	PAK4	S371	S376F	376	Missense	distal	5	no	21.189	21.055	EPSD	COSMIC	14.946	Down-regulation
STE_STE20_PAKB_PAK4_ST	P04637	TP53	O96013	PAK4	S371	G374S	374	Missense	distal	3	no	21.189	20.407	EPSD	COSMIC	14.946	Down-regulation
STE_STE20_PAKB_PAK4_ST	P04637	TP53	O96013	PAK4	S371	S376A	376	Missense	distal	5	no	21.189	21.182	EPSD	COSMIC	14.946	Down-regulation
STE_STE20_PAKB_PAK4_ST	P04637	TP53	O96013	PAK4	S371	S371P	371	Missense	central	0	yes	21.189	0.000	EPSD	COSMIC	14.946	Loss
STE_STE20_PAKB_PAK4_ST	P04637	TP53	O96013	PAK4	S376	K370N	370	Missense	distal	-6	no	18.237	17.994	EPSD	COSMIC	14.946	Down-regulation
STE_STE20_PAKB_PAK4_ST	P04637	TP53	O96013	PAK4	S376	L383F	383	Missense	distal	7	no	18.237	18.139	EPSD	COSMIC	14.946	Down-regulation
STE_STE20_PAKB_PAK4_ST	P04637	TP53	O96013	PAK4	S376	R379H	379	Missense	distal	3	no	18.237	18.601	EPSD	COSMIC	14.946	Up-regulation
STE_STE20_PAKB_PAK4_ST	P04637	TP53	O96013	PAK4	S376	H380Y	380	Missense	distal	4	no	18.237	18.306	EPSD	COSMIC	14.946	Up-regulation
STE_STE20_PAKB_PAK4_ST	P04637	TP53	O96013	PAK4	S376	T377I	377	Missense	proximal	1	no	18.237	18.420	EPSD	COSMIC	14.946	Up-regulation
STE_STE20_PAKB_PAK4_ST	P04637	TP53	O96013	PAK4	S376	S378F	378	Missense	proximal	2	no	18.237	16.934	EPSD	COSMIC	14.946	Down-regulation
STE_STE20_PAKB_PAK4_ST	P04637	TP53	O96013	PAK4	S376	K370Q	370	Missense	distal	-6	no	18.237	18.041	EPSD	COSMIC	14.946	Down-regulation
STE_STE20_PAKB_PAK4_ST	P04637	TP53	O96013	PAK4	S376	K381N	381	Missense	distal	5	no	18.237	18.039	EPSD	COSMIC	14.946	Down-regulation
STE_STE20_PAKB_PAK4_ST	P04637	TP53	O96013	PAK4	S376	R379P	379	Missense	distal	3	no	18.237	19.001	EPSD	COSMIC	14.946	Up-regulation
STE_STE20_PAKB_PAK4_ST	P04637	TP53	O96013	PAK4	S376	K373R	373	Missense	distal	-3	no	18.237	18.252	EPSD	COSMIC	14.946	Up-regulation
STE_STE20_PAKB_PAK4_ST	P04637	TP53	O96013	PAK4	S376	S376F	376	Missense	central	0	yes	18.237	0.000	EPSD	COSMIC	14.946	Loss
STE_STE20_PAKB_PAK4_ST	P04637	TP53	O96013	PAK4	S376	G374S	374	Missense	proximal	-2	no	18.237	19.679	EPSD	COSMIC	14.946	Up-regulation
STE_STE20_PAKB_PAK4_ST	P04637	TP53	O96013	PAK4	S376	S376A	376	Missense	central	0	yes	18.237	0.000	EPSD	COSMIC	14.946	Loss
STE_STE20_PAKB_PAK4_ST	P04637	TP53	O96013	PAK4	S376	S371P	371	Missense	distal	-5	no	18.237	17.995	EPSD	COSMIC	14.946	Down-regulation
STE_STE20_PAKB_PAK4_ST	P04637	TP53	O96013	PAK4	S378	L383F	383	Missense	distal	5	no	15.211	15.348	EPSD	COSMIC	14.946	Up-regulation
STE_STE20_PAKB_PAK4_ST	P04637	TP53	O96013	PAK4	S378	R379H	379	Missense	proximal	1	no	15.211	14.569	EPSD	COSMIC	14.946	Loss
STE_STE20_PAKB_PAK4_ST	P04637	TP53	O96013	PAK4	S378	S376T	376	Missense	proximal	-2	no	15.211	12.720	EPSD	COSMIC	14.946	Loss
STE_STE20_PAKB_PAK4_ST	P04637	TP53	O96013	PAK4	S378	H380Y	380	Missense	proximal	2	no	15.211	15.031	EPSD	COSMIC	14.946	Down-regulation
STE_STE20_PAKB_PAK4_ST	P04637	TP53	O96013	PAK4	S378	T377I	377	Missense	proximal	-1	no	15.211	15.861	EPSD	COSMIC	14.946	Up-regulation
STE_STE20_PAKB_PAK4_ST	P04637	TP53	O96013	PAK4	S378	S378F	378	Missense	central	0	yes	15.211	0.000	EPSD	COSMIC	14.946	Loss
STE_STE20_PAKB_PAK4_ST	P04637	TP53	O96013	PAK4	S378	K381N	381	Missense	distal	3	no	15.211	15.572	EPSD	COSMIC	14.946	Up-regulation
STE_STE20_PAKB_PAK4_ST	P04637	TP53	O96013	PAK4	S378	R379P	379	Missense	proximal	1	no	15.211	12.941	EPSD	COSMIC	14.946	Loss
STE_STE20_PAKB_PAK4_ST	P04637	TP53	O96013	PAK4	S378	M384I	384	Missense	distal	6	no	15.211	15.469	EPSD	COSMIC	14.946	Up-regulation
STE_STE20_PAKB_PAK4_ST	P04637	TP53	O96013	PAK4	S378	K373R	373	Missense	distal	-5	no	15.211	15.299	EPSD	COSMIC	14.946	Up-regulation
STE_STE20_PAKB_PAK4_ST	P04637	TP53	O96013	PAK4	S378	S376F	376	Missense	proximal	-2	no	15.211	16.212	EPSD	COSMIC	14.946	Up-regulation
STE_STE20_PAKB_PAK4_ST	P04637	TP53	O96013	PAK4	S378	G374S	374	Missense	distal	-4	no	15.211	16.204	EPSD	COSMIC	14.946	Up-regulation
STE_STE20_PAKB_PAK4_ST	P04637	TP53	O96013	PAK4	S378	S376A	376	Missense	proximal	-2	no	15.211	15.009	EPSD	COSMIC	14.946	Down-regulation
STE_STE20_PAKB_PAK4_ST	P04637	TP53	O96013	PAK4	S378	S371P	371	Missense	distal	-7	no	15.211	15.599	EPSD	COSMIC	14.946	Up-regulation
STE_STE20_PAKB_PAK4_ST	P53667	LIMK1	O96013	PAK4	S58	D54G	54	Missense	distal	-4	no	15.603	15.690	EPSD	COSMIC	14.946	Up-regulation
STE_STE20_PAKB_PAK4_ST	P53667	LIMK1	O96013	PAK4	S210	G207R	207	Missense	distal	-3	no	8.827	15.075	EPSD	COSMIC	14.946	Gain
STE_STE20_PAKB_PAK4_ST	P53667	LIMK1	O96013	PAK4	S296	R295W	295	Missense	proximal	-1	no	17.236	12.949	EPSD	COSMIC	14.946	Loss
STE_STE20_PAKB_PAK4_ST	P53667	LIMK1	O96013	PAK4	S302	R295W	295	Missense	distal	-7	no	16.285	13.039	EPSD	COSMIC	14.946	Loss
STE_STE20_PAKB_PAK4_ST	P53667	LIMK1	O96013	PAK4	S321	R320L	320	Missense	proximal	-1	no	16.722	13.427	EPSD	COSMIC;GDSC;CCLE	14.946	Loss
STE_STE20_PAKB_PAK4_ST	P53667	LIMK1	O96013	PAK4	S321	R320H	320	Missense	proximal	-1	no	16.722	14.343	EPSD	COSMIC	14.946	Loss
STE_STE20_PAKB_PAK4_ST	P53667	LIMK1	O96013	PAK4	S321	E322D	322	Missense	proximal	1	no	16.722	16.592	EPSD	COSMIC	14.946	Down-regulation
STE_STE20_PAKB_PAK4_ST	P53667	LIMK1	O96013	PAK4	S323	R320L	320	Missense	distal	-3	no	21.679	17.066	EPSD	COSMIC;GDSC;CCLE	14.946	Down-regulation
STE_STE20_PAKB_PAK4_ST	P53667	LIMK1	O96013	PAK4	S323	V326I	326	Missense	distal	3	no	21.679	21.342	EPSD	COSMIC	14.946	Down-regulation
STE_STE20_PAKB_PAK4_ST	P53667	LIMK1	O96013	PAK4	S323	R320H	320	Missense	distal	-3	no	21.679	17.673	EPSD	COSMIC	14.946	Down-regulation
STE_STE20_PAKB_PAK4_ST	P53667	LIMK1	O96013	PAK4	S323	E322D	322	Missense	proximal	-1	no	21.679	21.342	EPSD	COSMIC	14.946	Down-regulation
STE_STE20_PAKB_PAK4_ST	P53667	LIMK1	O96013	PAK4	S430	S435I	435	Missense	distal	5	no	17.595	17.457	EPSD	COSMIC	14.946	Down-regulation
STE_STE20_PAKB_PAK4_ST	P03372	ESR1	O96013	PAK4	S10	H6Y	6	Missense	distal	-4	no	15.151	14.508	EPSD	COSMIC;GDSC	14.946	Loss
STE_STE20_PAKB_PAK4_ST	P03372	ESR1	O96013	PAK4	S10	L15V	15	Missense	distal	5	no	15.151	15.286	EPSD	COSMIC	14.946	Up-regulation
STE_STE20_PAKB_PAK4_ST	P03372	ESR1	O96013	PAK4	S10	T4A	4	Missense	distal	-6	no	15.151	15.292	EPSD	COSMIC	14.946	Up-regulation
STE_STE20_PAKB_PAK4_ST	P03372	ESR1	O96013	PAK4	S10	G11D	11	Missense	proximal	1	no	15.151	14.966	EPSD	COSMIC	14.946	Down-regulation
STE_STE20_PAKB_PAK4_ST	P03372	ESR1	O96013	PAK4	S10	G11S	11	Missense	proximal	1	no	15.151	15.636	EPSD	COSMIC	14.946	Up-regulation
STE_STE20_PAKB_PAK4_ST	P03372	ESR1	O96013	PAK4	S167	G172R	172	Missense	distal	5	no	19.706	19.821	EPSD	COSMIC	14.946	Up-regulation
STE_STE20_PAKB_PAK4_ST	P03372	ESR1	O96013	PAK4	S167	M174I	174	Missense	distal	7	no	19.706	19.797	EPSD	COSMIC	14.946	Up-regulation
STE_STE20_PAKB_PAK4_ST	P03372	ESR1	O96013	PAK4	S167	D170Y	170	Missense	distal	3	no	19.706	19.002	EPSD	COSMIC	14.946	Down-regulation
STE_STE20_PAKB_PAK4_ST	P03372	ESR1	O96013	PAK4	S167	G160D	160	Missense	distal	-7	no	19.706	20.106	EPSD	COSMIC	14.946	Up-regulation
STE_STE20_PAKB_PAK4_ST	P03372	ESR1	O96013	PAK4	S212	K206T	206	Missense	distal	-6	no	16.546	16.285	EPSD	COSMIC	14.946	Down-regulation
STE_STE20_PAKB_PAK4_ST	P03372	ESR1	O96013	PAK4	S212	R211I	211	Missense	proximal	-1	no	16.546	13.126	EPSD	COSMIC	14.946	Loss
STE_STE20_PAKB_PAK4_ST	P03372	ESR1	O96013	PAK4	S212	Q214E	214	Missense	proximal	2	no	16.546	16.893	EPSD	COSMIC	14.946	Up-regulation
STE_STE20_PAKB_PAK4_ST	P03372	ESR1	O96013	PAK4	S212	R211S	211	Missense	proximal	-1	no	16.546	14.399	EPSD	COSMIC	14.946	Loss
STE_STE20_PAKB_PAK4_ST	P03372	ESR1	O96013	PAK4	S212	I213N	213	Missense	proximal	1	no	16.546	16.964	EPSD	COSMIC	14.946	Up-regulation
STE_STE20_PAKB_PAK4_ST	P03372	ESR1	O96013	PAK4	S236	R241G	241	Missense	distal	5	no	17.263	17.148	EPSD	COSMIC	14.946	Down-regulation
STE_STE20_PAKB_PAK4_ST	P03372	ESR1	O96013	PAK4	S236	R241W	241	Missense	distal	5	no	17.263	17.025	EPSD	COSMIC	14.946	Down-regulation
STE_STE20_PAKB_PAK4_ST	P03372	ESR1	O96013	PAK4	S236	R233G	233	Missense	distal	-3	no	17.263	11.015	EPSD	COSMIC	14.946	Loss
STE_STE20_PAKB_PAK4_ST	P03372	ESR1	O96013	PAK4	S236	C237Y	237	Missense	proximal	1	no	17.263	17.553	EPSD	COSMIC	14.946	Up-regulation
STE_STE20_PAKB_PAK4_ST	P03372	ESR1	O96013	PAK4	S236	Q238H	238	Missense	proximal	2	no	17.263	16.850	EPSD	COSMIC;CCLE	14.946	Down-regulation
STE_STE20_PAKB_PAK4_ST	P03372	ESR1	O96013	PAK4	S236	R243L	243	Missense	distal	7	no	17.263	17.653	EPSD	COSMIC	14.946	Up-regulation
STE_STE20_PAKB_PAK4_ST	P03372	ESR1	O96013	PAK4	S305	K303R	303	Missense	proximal	-2	no	28.139	28.073	PhosphoSitePlus	COSMIC	14.946	Down-regulation
STE_STE20_PAKB_PAK4_ST	P03372	ESR1	O96013	PAK4	S305	K299R	299	Missense	distal	-6	no	28.139	28.123	PhosphoSitePlus	COSMIC	14.946	Down-regulation
STE_STE20_PAKB_PAK4_ST	P03372	ESR1	O96013	PAK4	S305	N304S	304	Missense	proximal	-1	no	28.139	29.364	PhosphoSitePlus	COSMIC	14.946	Up-regulation
STE_STE20_PAKB_PAK4_ST	P03372	ESR1	O96013	PAK4	S305	R300C	300	Missense	distal	-5	no	28.139	27.216	PhosphoSitePlus	COSMIC;CCLE	14.946	Down-regulation
STE_STE20_PAKB_PAK4_ST	P03372	ESR1	O96013	PAK4	S305	A307P	307	Missense	proximal	2	no	28.139	27.861	PhosphoSitePlus	COSMIC	14.946	Down-regulation
STE_STE20_PAKB_PAK4_ST	P03372	ESR1	O96013	PAK4	S305	N304H	304	Missense	proximal	-1	no	28.139	29.132	PhosphoSitePlus	COSMIC	14.946	Up-regulation
STE_STE20_PAKB_PAK4_ST	P03372	ESR1	O96013	PAK4	S559	G557R	557	Missense	proximal	-2	no	12.039	16.726	EPSD	COSMIC	14.946	Gain
STE_STE20_PAKB_PAK4_ST	P03372	ESR1	O96013	PAK4	S576	S578Y	578	Missense	proximal	2	no	16.807	15.762	EPSD	COSMIC	14.946	Down-regulation
STE_STE20_PAKB_PAK4_ST	Q93045	STMN2	O96013	PAK4	S16	I21T	21	Missense	distal	5	no	15.340	15.518	EPSD	COSMIC	14.946	Up-regulation
STE_STE20_PAKB_PAK4_ST	Q93045	STMN2	O96013	PAK4	S16	S23F	23	Missense	distal	7	no	15.340	15.614	EPSD	COSMIC	14.946	Up-regulation
STE_STE20_PAKB_PAK4_ST	Q93045	STMN2	O96013	PAK4	S50	E55D	55	Missense	distal	5	no	25.990	25.946	PhosphoSitePlus	COSMIC	14.946	Down-regulation
STE_STE20_PAKB_PAK4_ST	Q93045	STMN2	O96013	PAK4	S50	S50F	50	Missense	central	0	yes	25.990	0.000	PhosphoSitePlus	COSMIC	14.946	Loss
STE_STE20_PAKB_PAK4_ST	Q93045	STMN2	O96013	PAK4	S50	R48H	48	Missense	proximal	-2	no	25.990	24.700	PhosphoSitePlus	COSMIC	14.946	Down-regulation
STE_STE20_PAKB_PAK4_ST	Q93045	STMN2	O96013	PAK4	S80	K76Q	76	Missense	distal	-4	no	15.305	14.702	EPSD	COSMIC	14.946	Loss
STE_STE20_PAKB_PAK4_ST	Q93045	STMN2	O96013	PAK4	S80	L79R	79	Missense	proximal	-1	no	15.305	18.600	EPSD	COSMIC	14.946	Up-regulation
STE_STE20_PAKB_PAK4_ST	Q93045	STMN2	O96013	PAK4	S80	K87Q	87	Missense	distal	7	no	15.305	15.368	EPSD	COSMIC;GDSC;CCLE	14.946	Up-regulation
STE_STE20_PAKB_PAK4_ST	Q93045	STMN2	O96013	PAK4	S80	D78E	78	Missense	proximal	-2	no	15.305	15.878	EPSD	COSMIC	14.946	Up-regulation
STE_STE20_PAKB_PAK4_ST	Q93045	STMN2	O96013	PAK4	S80	L79M	79	Missense	proximal	-1	no	15.305	16.547	EPSD	COSMIC	14.946	Up-regulation
STE_STE20_PAKB_PAK4_ST	Q93045	STMN2	O96013	PAK4	S80	S73Y	73	Missense	distal	-7	no	15.305	14.359	EPSD	COSMIC	14.946	Loss
STE_STE20_PAKB_PAK4_ST	Q93045	STMN2	O96013	PAK4	S97	R94K	94	Missense	distal	-3	no	24.764	24.748	EPSD	COSMIC	14.946	Down-regulation
STE_STE20_PAKB_PAK4_ST	Q93045	STMN2	O96013	PAK4	S97	A90T	90	Missense	distal	-7	no	24.764	23.450	EPSD	COSMIC	14.946	Down-regulation
CAMK_MLCK_MYLK2_ST	Q06413	MEF2C	Q9H1R3	MYLK2	T70	E74K	74	Missense	distal	4	no	3.520	3.484	EPSD	COSMIC	3.166	Down-regulation
CAMK_MLCK_MYLK2_ST	Q06413	MEF2C	Q9H1R3	MYLK2	T70	P75L	75	Missense	distal	5	no	3.520	3.702	EPSD	COSMIC	3.166	Up-regulation
CAMK_MLCK_MYLK2_ST	Q06413	MEF2C	Q9H1R3	MYLK2	T70	E77K	77	Missense	distal	7	no	3.520	3.382	EPSD	COSMIC	3.166	Down-regulation
CAMK_MLCK_MYLK2_ST	Q06413	MEF2C	Q9H1R3	MYLK2	T70	L67P	67	Missense	distal	-3	no	3.520	3.515	EPSD	COSMIC	3.166	Down-regulation
CAMK_MLCK_MYLK2_ST	Q06413	MEF2C	Q9H1R3	MYLK2	T80	V85A	85	Missense	distal	5	no	7.263	7.000	PhosphoSitePlus	COSMIC	3.166	Down-regulation
CAMK_MLCK_MYLK2_ST	Q06413	MEF2C	Q9H1R3	MYLK2	T80	E74K	74	Missense	distal	-6	no	7.263	8.103	PhosphoSitePlus	COSMIC	3.166	Up-regulation
CAMK_MLCK_MYLK2_ST	Q06413	MEF2C	Q9H1R3	MYLK2	T80	P75L	75	Missense	distal	-5	no	7.263	7.183	PhosphoSitePlus	COSMIC	3.166	Down-regulation
CAMK_MLCK_MYLK2_ST	Q06413	MEF2C	Q9H1R3	MYLK2	T80	S78T	78	Missense	proximal	-2	no	7.263	7.172	PhosphoSitePlus	COSMIC	3.166	Down-regulation
CAMK_MLCK_MYLK2_ST	Q06413	MEF2C	Q9H1R3	MYLK2	T80	R79W	79	Missense	proximal	-1	no	7.263	7.248	PhosphoSitePlus	COSMIC	3.166	Down-regulation
CAMK_MLCK_MYLK2_ST	Q06413	MEF2C	Q9H1R3	MYLK2	T80	E77K	77	Missense	distal	-3	no	7.263	7.228	PhosphoSitePlus	COSMIC	3.166	Down-regulation
CAMK_MLCK_MYLK2_ST	Q06413	MEF2C	Q9H1R3	MYLK2	S396	D400Y	400	Missense	distal	4	no	3.137	3.174	EPSD	COSMIC	3.166	Gain
CAMK_MLCK_MYLK2_ST	Q06413	MEF2C	Q9H1R3	MYLK2	S396	I390M	390	Missense	distal	-6	no	3.137	3.375	EPSD	COSMIC	3.166	Gain
CAMK_MLCK_MYLK2_ST	Q06413	MEF2C	Q9H1R3	MYLK2	S396	R401T	401	Missense	distal	5	no	3.137	3.178	EPSD	COSMIC	3.166	Gain
CAMK_MLCK_MYLK2_ST	Q06413	MEF2C	Q9H1R3	MYLK2	S396	R401K	401	Missense	distal	5	no	3.137	3.256	EPSD	COSMIC	3.166	Gain
CAMK_MLCK_MYLK2_ST	Q06413	MEF2C	Q9H1R3	MYLK2	S396	P394R	394	Missense	proximal	-2	no	3.137	3.243	EPSD	COSMIC	3.166	Gain
CAMK_MLCK_MYLK2_ST	Q06413	MEF2C	Q9H1R3	MYLK2	S396	P394T	394	Missense	proximal	-2	no	3.137	3.210	EPSD	COSMIC	3.166	Gain
CAMK_RAD53_CHEK2_ST	P04637	TP53	O96017	CHEK2	S15	E11Q	11	Missense	distal	-4	no	10.671	11.786	EPSD;PhosphoSitePlus	COSMIC;GDSC;CCLE	8.561	Up-regulation
CAMK_RAD53_CHEK2_ST	P04637	TP53	O96017	CHEK2	S15	S20L	20	Missense	distal	5	no	10.671	10.474	EPSD;PhosphoSitePlus	COSMIC	8.561	Down-regulation
CAMK_RAD53_CHEK2_ST	P04637	TP53	O96017	CHEK2	S15	Q16L	16	Missense	proximal	1	no	10.671	9.435	EPSD;PhosphoSitePlus	COSMIC;GDSC;CCLE	8.561	Down-regulation
CAMK_RAD53_CHEK2_ST	P04637	TP53	O96017	CHEK2	S15	P13S	13	Missense	proximal	-2	no	10.671	10.908	EPSD;PhosphoSitePlus	COSMIC	8.561	Up-regulation
CAMK_RAD53_CHEK2_ST	P04637	TP53	O96017	CHEK2	S15	E17K	17	Missense	proximal	2	no	10.671	10.757	EPSD;PhosphoSitePlus	COSMIC	8.561	Up-regulation
CAMK_RAD53_CHEK2_ST	P04637	TP53	O96017	CHEK2	S15	V10I	10	Missense	distal	-5	no	10.671	10.878	EPSD;PhosphoSitePlus	COSMIC	8.561	Up-regulation
CAMK_RAD53_CHEK2_ST	P04637	TP53	O96017	CHEK2	S15	P8L	8	Missense	distal	-7	no	10.671	9.962	EPSD;PhosphoSitePlus	COSMIC	8.561	Down-regulation
CAMK_RAD53_CHEK2_ST	P04637	TP53	O96017	CHEK2	S15	P8S	8	Missense	distal	-7	no	10.671	10.908	EPSD;PhosphoSitePlus	COSMIC	8.561	Up-regulation
CAMK_RAD53_CHEK2_ST	P04637	TP53	O96017	CHEK2	S15	P13L	13	Missense	proximal	-2	no	10.671	10.623	EPSD;PhosphoSitePlus	COSMIC	8.561	Down-regulation
CAMK_RAD53_CHEK2_ST	P04637	TP53	O96017	CHEK2	S15	V10G	10	Missense	distal	-5	no	10.671	10.171	EPSD;PhosphoSitePlus	COSMIC	8.561	Down-regulation
CAMK_RAD53_CHEK2_ST	P04637	TP53	O96017	CHEK2	S15	T18A	18	Missense	distal	3	no	10.671	10.497	EPSD;PhosphoSitePlus	COSMIC	8.561	Down-regulation
CAMK_RAD53_CHEK2_ST	P04637	TP53	O96017	CHEK2	S15	F19S	19	Missense	distal	4	no	10.671	9.680	EPSD;PhosphoSitePlus	COSMIC	8.561	Down-regulation
CAMK_RAD53_CHEK2_ST	P04637	TP53	O96017	CHEK2	S15	E17V	17	Missense	proximal	2	no	10.671	10.592	EPSD;PhosphoSitePlus	COSMIC	8.561	Down-regulation
CAMK_RAD53_CHEK2_ST	P04637	TP53	O96017	CHEK2	S15	S9G	9	Missense	distal	-6	no	10.671	10.403	EPSD;PhosphoSitePlus	COSMIC	8.561	Down-regulation
CAMK_RAD53_CHEK2_ST	P04637	TP53	O96017	CHEK2	S15	T18I	18	Missense	distal	3	no	10.671	11.257	EPSD;PhosphoSitePlus	COSMIC	8.561	Up-regulation
CAMK_RAD53_CHEK2_ST	P04637	TP53	O96017	CHEK2	S15	T18K	18	Missense	distal	3	no	10.671	11.209	EPSD;PhosphoSitePlus	COSMIC	8.561	Up-regulation
CAMK_RAD53_CHEK2_ST	P04637	TP53	O96017	CHEK2	S15	T18R	18	Missense	distal	3	no	10.671	10.408	EPSD;PhosphoSitePlus	COSMIC	8.561	Down-regulation
CAMK_RAD53_CHEK2_ST	P04637	TP53	O96017	CHEK2	S15	S15I	15	Missense	central	0	yes	10.671	0.000	EPSD;PhosphoSitePlus	COSMIC	8.561	Loss
CAMK_RAD53_CHEK2_ST	P04637	TP53	O96017	CHEK2	S20	E17K	17	Missense	distal	-3	no	7.530	10.357	EPSD;PhosphoSitePlus	COSMIC	8.561	Gain
CAMK_RAD53_CHEK2_ST	P04637	TP53	O96017	CHEK2	S37	M40I	40	Missense	distal	3	no	10.326	10.634	EPSD;PhosphoSitePlus	COSMIC	8.561	Up-regulation
CAMK_RAD53_CHEK2_ST	P04637	TP53	O96017	CHEK2	S37	V31I	31	Missense	distal	-6	no	10.326	10.208	EPSD;PhosphoSitePlus	COSMIC;GDSC;CCLE	8.561	Down-regulation
CAMK_RAD53_CHEK2_ST	P04637	TP53	O96017	CHEK2	S37	P36L	36	Missense	proximal	-1	no	10.326	10.304	EPSD;PhosphoSitePlus	COSMIC;GDSC;CCLE	8.561	Down-regulation
CAMK_RAD53_CHEK2_ST	P04637	TP53	O96017	CHEK2	S37	S33T	33	Missense	distal	-4	no	10.326	9.387	EPSD;PhosphoSitePlus	COSMIC	8.561	Down-regulation
CAMK_RAD53_CHEK2_ST	P04637	TP53	O96017	CHEK2	S37	D41N	41	Missense	distal	4	no	10.326	9.967	EPSD;PhosphoSitePlus	COSMIC	8.561	Down-regulation
CAMK_RAD53_CHEK2_ST	P04637	TP53	O96017	CHEK2	S37	L35F	35	Missense	proximal	-2	no	10.326	9.237	EPSD;PhosphoSitePlus	COSMIC	8.561	Down-regulation
CAMK_RAD53_CHEK2_ST	P04637	TP53	O96017	CHEK2	S37	Q38L	38	Missense	proximal	1	no	10.326	9.090	EPSD;PhosphoSitePlus	COSMIC	8.561	Down-regulation
CAMK_RAD53_CHEK2_ST	P04637	TP53	O96017	CHEK2	S37	M44I	44	Missense	distal	7	no	10.326	10.335	EPSD;PhosphoSitePlus	COSMIC	8.561	Up-regulation
CAMK_RAD53_CHEK2_ST	P04637	TP53	O96017	CHEK2	S37	P36S	36	Missense	proximal	-1	no	10.326	10.506	EPSD;PhosphoSitePlus	COSMIC;GDSC;CCLE	8.561	Up-regulation
CAMK_RAD53_CHEK2_ST	P04637	TP53	O96017	CHEK2	S37	A39V	39	Missense	proximal	2	no	10.326	10.172	EPSD;PhosphoSitePlus	COSMIC	8.561	Down-regulation
CAMK_RAD53_CHEK2_ST	P04637	TP53	O96017	CHEK2	S37	A39S	39	Missense	proximal	2	no	10.326	10.376	EPSD;PhosphoSitePlus	COSMIC	8.561	Up-regulation
CAMK_RAD53_CHEK2_ST	P04637	TP53	O96017	CHEK2	S37	D42Y	42	Missense	distal	5	no	10.326	10.249	EPSD;PhosphoSitePlus	COSMIC	8.561	Down-regulation
CAMK_RAD53_CHEK2_ST	P04637	TP53	O96017	CHEK2	S37	M44R	44	Missense	distal	7	no	10.326	10.305	EPSD;PhosphoSitePlus	COSMIC	8.561	Down-regulation
CAMK_RAD53_CHEK2_ST	P04637	TP53	O96017	CHEK2	S37	M44V	44	Missense	distal	7	no	10.326	10.322	EPSD;PhosphoSitePlus	COSMIC	8.561	Down-regulation
CAMK_RAD53_CHEK2_ST	P04637	TP53	O96017	CHEK2	S37	N30K	30	Missense	distal	-7	no	10.326	11.028	EPSD;PhosphoSitePlus	COSMIC	8.561	Up-regulation
CAMK_RAD53_CHEK2_ST	P04637	TP53	O96017	CHEK2	S37	M44T	44	Missense	distal	7	no	10.326	10.317	EPSD;PhosphoSitePlus	COSMIC	8.561	Down-regulation
CAMK_RAD53_CHEK2_ST	P04637	TP53	O96017	CHEK2	S37	A39T	39	Missense	proximal	2	no	10.326	10.251	EPSD;PhosphoSitePlus	COSMIC	8.561	Down-regulation
CAMK_RAD53_CHEK2_ST	P04637	TP53	O96017	CHEK2	S37	L43F	43	Missense	distal	6	no	10.326	9.687	EPSD;PhosphoSitePlus	COSMIC	8.561	Down-regulation
CAMK_RAD53_CHEK2_ST	P04637	TP53	O96017	CHEK2	S37	D41H	41	Missense	distal	4	no	10.326	9.651	EPSD;PhosphoSitePlus	COSMIC	8.561	Down-regulation
CAMK_RAD53_CHEK2_ST	P04637	TP53	O96017	CHEK2	S37	P36R	36	Missense	proximal	-1	no	10.326	10.198	EPSD;PhosphoSitePlus	COSMIC	8.561	Down-regulation
CAMK_RAD53_CHEK2_ST	P04637	TP53	O96017	CHEK2	S37	L35R	35	Missense	proximal	-2	no	10.326	10.881	EPSD;PhosphoSitePlus	COSMIC	8.561	Up-regulation
CAMK_RAD53_CHEK2_ST	P04637	TP53	O96017	CHEK2	S37	L35H	35	Missense	proximal	-2	no	10.326	10.535	EPSD;PhosphoSitePlus	COSMIC	8.561	Up-regulation
CAMK_RAD53_CHEK2_ST	P04637	TP53	O96017	CHEK2	S37	L35P	35	Missense	proximal	-2	no	10.326	10.375	EPSD;PhosphoSitePlus	COSMIC	8.561	Up-regulation
CAMK_RAD53_CHEK2_ST	P04637	TP53	O96017	CHEK2	S37	L35I	35	Missense	proximal	-2	no	10.326	10.348	EPSD;PhosphoSitePlus	COSMIC	8.561	Up-regulation
CAMK_RAD53_CHEK2_ST	P04637	TP53	O96017	CHEK2	S37	L35V	35	Missense	proximal	-2	no	10.326	10.334	EPSD;PhosphoSitePlus	COSMIC	8.561	Up-regulation
CAMK_RAD53_CHEK2_ST	P04637	TP53	O96017	CHEK2	S37	D41E	41	Missense	distal	4	no	10.326	9.690	EPSD;PhosphoSitePlus	COSMIC	8.561	Down-regulation
CAMK_RAD53_CHEK2_ST	P04637	TP53	O96017	CHEK2	T81	P77A	77	Missense	distal	-4	no	9.581	10.130	EPSD	COSMIC	8.561	Up-regulation
CAMK_RAD53_CHEK2_ST	P04637	TP53	O96017	CHEK2	T81	A76T	76	Missense	distal	-5	no	9.581	10.096	EPSD	COSMIC	8.561	Up-regulation
CAMK_RAD53_CHEK2_ST	P04637	TP53	O96017	CHEK2	T81	A83T	83	Missense	proximal	2	no	9.581	9.506	EPSD	COSMIC	8.561	Down-regulation
CAMK_RAD53_CHEK2_ST	P04637	TP53	O96017	CHEK2	T81	T81I	81	Missense	central	0	yes	9.581	0.000	EPSD	COSMIC	8.561	Loss
CAMK_RAD53_CHEK2_ST	P04637	TP53	O96017	CHEK2	T81	A84V	84	Missense	distal	3	no	9.581	10.245	EPSD	COSMIC	8.561	Up-regulation
CAMK_RAD53_CHEK2_ST	P04637	TP53	O96017	CHEK2	T81	P80L	80	Missense	proximal	-1	no	9.581	9.559	EPSD	COSMIC	8.561	Down-regulation
CAMK_RAD53_CHEK2_ST	P04637	TP53	O96017	CHEK2	T81	A86V	86	Missense	distal	5	no	9.581	9.452	EPSD	COSMIC	8.561	Down-regulation
CAMK_RAD53_CHEK2_ST	P04637	TP53	O96017	CHEK2	T81	P85S	85	Missense	distal	4	no	9.581	9.354	EPSD	COSMIC	8.561	Down-regulation
CAMK_RAD53_CHEK2_ST	P04637	TP53	O96017	CHEK2	T81	A79T	79	Missense	proximal	-2	no	9.581	9.435	EPSD	COSMIC	8.561	Down-regulation
CAMK_RAD53_CHEK2_ST	P04637	TP53	O96017	CHEK2	T81	A84G	84	Missense	distal	3	no	9.581	10.291	EPSD	COSMIC	8.561	Up-regulation
CAMK_RAD53_CHEK2_ST	P04637	TP53	O96017	CHEK2	T81	A78V	78	Missense	distal	-3	no	9.581	5.850	EPSD	COSMIC	8.561	Loss
CAMK_RAD53_CHEK2_ST	P04637	TP53	O96017	CHEK2	T81	A78S	78	Missense	distal	-3	no	9.581	8.437	EPSD	COSMIC	8.561	Loss
CAMK_RAD53_CHEK2_ST	P04637	TP53	O96017	CHEK2	T81	P87L	87	Missense	distal	6	no	9.581	9.434	EPSD	COSMIC	8.561	Down-regulation
CAMK_RAD53_CHEK2_ST	P04637	TP53	O96017	CHEK2	T81	P85L	85	Missense	distal	4	no	9.581	9.673	EPSD	COSMIC	8.561	Up-regulation
CAMK_RAD53_CHEK2_ST	P04637	TP53	O96017	CHEK2	T81	P82S	82	Missense	proximal	1	no	9.581	8.063	EPSD	COSMIC	8.561	Loss
CAMK_RAD53_CHEK2_ST	P04637	TP53	O96017	CHEK2	T81	P77S	77	Missense	distal	-4	no	9.581	10.290	EPSD	COSMIC	8.561	Up-regulation
CAMK_RAD53_CHEK2_ST	P04637	TP53	O96017	CHEK2	T81	P80S	80	Missense	proximal	-1	no	9.581	9.761	EPSD	COSMIC	8.561	Up-regulation
CAMK_RAD53_CHEK2_ST	P04637	TP53	O96017	CHEK2	T81	A84T	84	Missense	distal	3	no	9.581	9.755	EPSD	COSMIC	8.561	Up-regulation
CAMK_RAD53_CHEK2_ST	P04637	TP53	O96017	CHEK2	T81	A83E	83	Missense	proximal	2	no	9.581	9.506	EPSD	COSMIC	8.561	Down-regulation
CAMK_RAD53_CHEK2_ST	P04637	TP53	O96017	CHEK2	T81	P85T	85	Missense	distal	4	no	9.581	9.618	EPSD	COSMIC	8.561	Up-regulation
CAMK_RAD53_CHEK2_ST	P04637	TP53	O96017	CHEK2	T81	A74V	74	Missense	distal	-7	no	9.581	8.985	EPSD	COSMIC	8.561	Down-regulation
CAMK_RAD53_CHEK2_ST	P04637	TP53	O96017	CHEK2	T81	P75S	75	Missense	distal	-6	no	9.581	9.706	EPSD	COSMIC	8.561	Up-regulation
CAMK_RAD53_CHEK2_ST	P04637	TP53	O96017	CHEK2	T81	A76V	76	Missense	distal	-5	no	9.581	9.506	EPSD	COSMIC	8.561	Down-regulation
CAMK_RAD53_CHEK2_ST	P04637	TP53	O96017	CHEK2	T81	P75R	75	Missense	distal	-6	no	9.581	9.657	EPSD	COSMIC	8.561	Up-regulation
CAMK_RAD53_CHEK2_ST	P04637	TP53	O96017	CHEK2	T81	P87H	87	Missense	distal	6	no	9.581	9.654	EPSD	COSMIC	8.561	Up-regulation
CAMK_RAD53_CHEK2_ST	P04637	TP53	O96017	CHEK2	T81	P87T	87	Missense	distal	6	no	9.581	9.509	EPSD	COSMIC	8.561	Down-regulation
CAMK_RAD53_CHEK2_ST	P04637	TP53	O96017	CHEK2	T81	P87S	87	Missense	distal	6	no	9.581	9.503	EPSD	COSMIC	8.561	Down-regulation
CAMK_RAD53_CHEK2_ST	P04637	TP53	O96017	CHEK2	T81	P87R	87	Missense	distal	6	no	9.581	9.568	EPSD	COSMIC	8.561	Down-regulation
CAMK_RAD53_CHEK2_ST	P04637	TP53	O96017	CHEK2	T81	P87C	87	Missense	distal	6	no	9.581	9.362	EPSD	COSMIC	8.561	Down-regulation
CAMK_RAD53_CHEK2_ST	P04637	TP53	O96017	CHEK2	T81	A86E	86	Missense	distal	5	no	9.581	9.475	EPSD	COSMIC	8.561	Down-regulation
CAMK_RAD53_CHEK2_ST	P04637	TP53	O96017	CHEK2	T81	A86S	86	Missense	distal	5	no	9.581	9.604	EPSD	COSMIC	8.561	Up-regulation
CAMK_RAD53_CHEK2_ST	P04637	TP53	O96017	CHEK2	T81	A83V	83	Missense	proximal	2	no	9.581	9.426	EPSD	COSMIC	8.561	Down-regulation
CAMK_RAD53_CHEK2_ST	P04637	TP53	O96017	CHEK2	S99	S99F	99	Missense	central	0	yes	8.743	0.000	EPSD	COSMIC	8.561	Loss
CAMK_RAD53_CHEK2_ST	P04637	TP53	O96017	CHEK2	S99	S96F	96	Missense	distal	-3	no	8.743	-2.632	EPSD	COSMIC	8.561	Loss
CAMK_RAD53_CHEK2_ST	P04637	TP53	O96017	CHEK2	S99	P98S	98	Missense	proximal	-1	no	8.743	8.922	EPSD	COSMIC;CCLE	8.561	Up-regulation
CAMK_RAD53_CHEK2_ST	P04637	TP53	O96017	CHEK2	S99	T102I	102	Missense	distal	3	no	8.743	9.329	EPSD	COSMIC	8.561	Up-regulation
CAMK_RAD53_CHEK2_ST	P04637	TP53	O96017	CHEK2	S99	S94P	94	Missense	distal	-5	no	8.743	9.303	EPSD	COSMIC	8.561	Up-regulation
CAMK_RAD53_CHEK2_ST	P04637	TP53	O96017	CHEK2	S99	K101R	101	Missense	proximal	2	no	8.743	8.797	EPSD	COSMIC	8.561	Up-regulation
CAMK_RAD53_CHEK2_ST	P04637	TP53	O96017	CHEK2	S99	S94T	94	Missense	distal	-5	no	8.743	9.159	EPSD	COSMIC	8.561	Up-regulation
CAMK_RAD53_CHEK2_ST	P04637	TP53	O96017	CHEK2	S99	P98L	98	Missense	proximal	-1	no	8.743	8.721	EPSD	COSMIC;GDSC;CCLE	8.561	Down-regulation
CAMK_RAD53_CHEK2_ST	P04637	TP53	O96017	CHEK2	S99	S95F	95	Missense	distal	-4	no	8.743	5.861	EPSD	COSMIC;CCLE	8.561	Loss
CAMK_RAD53_CHEK2_ST	P04637	TP53	O96017	CHEK2	S99	S96C	96	Missense	distal	-3	no	8.743	4.678	EPSD	COSMIC	8.561	Loss
CAMK_RAD53_CHEK2_ST	P04637	TP53	O96017	CHEK2	S99	S106I	106	Missense	distal	7	no	8.743	8.775	EPSD	COSMIC	8.561	Up-regulation
CAMK_RAD53_CHEK2_ST	P04637	TP53	O96017	CHEK2	S99	P98F	98	Missense	proximal	-1	no	8.743	9.322	EPSD	COSMIC	8.561	Up-regulation
CAMK_RAD53_CHEK2_ST	P04637	TP53	O96017	CHEK2	S99	T102P	102	Missense	distal	3	no	8.743	8.762	EPSD	COSMIC	8.561	Up-regulation
CAMK_RAD53_CHEK2_ST	P04637	TP53	O96017	CHEK2	S99	S94L	94	Missense	distal	-5	no	8.743	9.092	EPSD	COSMIC	8.561	Up-regulation
CAMK_RAD53_CHEK2_ST	P04637	TP53	O96017	CHEK2	S99	S96P	96	Missense	distal	-3	no	8.743	9.874	EPSD	COSMIC	8.561	Up-regulation
CAMK_RAD53_CHEK2_ST	P04637	TP53	O96017	CHEK2	S99	P98T	98	Missense	proximal	-1	no	8.743	8.930	EPSD	COSMIC	8.561	Up-regulation
CAMK_RAD53_CHEK2_ST	P04637	TP53	O96017	CHEK2	S99	S96Y	96	Missense	distal	-3	no	8.743	2.027	EPSD	COSMIC	8.561	Loss
CAMK_RAD53_CHEK2_ST	P04637	TP53	O96017	CHEK2	S99	S99P	99	Missense	central	0	yes	8.743	0.000	EPSD	COSMIC	8.561	Loss
CAMK_RAD53_CHEK2_ST	P04637	TP53	O96017	CHEK2	S99	V97I	97	Missense	proximal	-2	no	8.743	8.757	EPSD	COSMIC	8.561	Up-regulation
CAMK_RAD53_CHEK2_ST	P04637	TP53	O96017	CHEK2	S99	Q104H	104	Missense	distal	5	no	8.743	8.723	EPSD	COSMIC	8.561	Down-regulation
CAMK_RAD53_CHEK2_ST	P04637	TP53	O96017	CHEK2	S99	L93M	93	Missense	distal	-6	no	8.743	8.659	EPSD	COSMIC	8.561	Down-regulation
CAMK_RAD53_CHEK2_ST	P04637	TP53	O96017	CHEK2	S99	K101N	101	Missense	proximal	2	no	8.743	8.641	EPSD	COSMIC	8.561	Down-regulation
CAMK_RAD53_CHEK2_ST	P04637	TP53	O96017	CHEK2	S99	V97A	97	Missense	proximal	-2	no	8.743	9.184	EPSD	COSMIC	8.561	Up-regulation
CAMK_RAD53_CHEK2_ST	P04637	TP53	O96017	CHEK2	S99	P92A	92	Missense	distal	-7	no	8.743	7.914	EPSD	COSMIC	8.561	Loss
CAMK_RAD53_CHEK2_ST	P04637	TP53	O96017	CHEK2	S99	Q104L	104	Missense	distal	5	no	8.743	8.580	EPSD	COSMIC	8.561	Down-regulation
CAMK_RAD53_CHEK2_ST	P04637	TP53	O96017	CHEK2	S99	P92L	92	Missense	distal	-7	no	8.743	8.033	EPSD	COSMIC	8.561	Loss
CAMK_RAD53_CHEK2_ST	P04637	TP53	O96017	CHEK2	S99	L93P	93	Missense	distal	-6	no	8.743	8.943	EPSD	COSMIC	8.561	Up-regulation
CAMK_RAD53_CHEK2_ST	P04637	TP53	O96017	CHEK2	S99	L93F	93	Missense	distal	-6	no	8.743	8.378	EPSD	COSMIC	8.561	Loss
CAMK_RAD53_CHEK2_ST	P04637	TP53	O96017	CHEK2	S99	L93H	93	Missense	distal	-6	no	8.743	8.978	EPSD	COSMIC	8.561	Up-regulation
CAMK_RAD53_CHEK2_ST	P04637	TP53	O96017	CHEK2	S99	S95Y	95	Missense	distal	-4	no	8.743	6.219	EPSD	COSMIC	8.561	Loss
CAMK_RAD53_CHEK2_ST	P04637	TP53	O96017	CHEK2	S149	W146R	146	Missense	distal	-3	no	-1.525	11.703	EPSD	COSMIC	8.561	Gain
CAMK_RAD53_CHEK2_ST	P04637	TP53	O96017	CHEK2	T155	P152H	152	Missense	distal	-3	no	6.638	8.632	EPSD	COSMIC	8.561	Gain
CAMK_RAD53_CHEK2_ST	P04637	TP53	O96017	CHEK2	T155	D148H	148	Missense	distal	-7	no	6.638	8.585	EPSD	COSMIC	8.561	Gain
CAMK_RAD53_CHEK2_ST	P04637	TP53	O96017	CHEK2	T211	D208H	208	Missense	distal	-3	no	3.113	8.619	EPSD	COSMIC	8.561	Gain
CAMK_RAD53_CHEK2_ST	P04637	TP53	O96017	CHEK2	S269	A276S	276	Missense	distal	7	no	12.111	12.099	EPSD	COSMIC	8.561	Down-regulation
CAMK_RAD53_CHEK2_ST	P04637	TP53	O96017	CHEK2	S269	G262H	262	Missense	distal	-7	no	12.111	12.545	EPSD	COSMIC	8.561	Up-regulation
CAMK_RAD53_CHEK2_ST	P04637	TP53	O96017	CHEK2	S269	N263H	263	Missense	distal	-6	no	12.111	12.389	EPSD	COSMIC	8.561	Up-regulation
CAMK_RAD53_CHEK2_ST	P04637	TP53	O96017	CHEK2	S269	G266A	266	Missense	distal	-3	no	12.111	12.303	EPSD	COSMIC	8.561	Up-regulation
CAMK_RAD53_CHEK2_ST	P04637	TP53	O96017	CHEK2	S269	S269N	269	Missense	central	0	yes	12.111	0.000	EPSD	COSMIC	8.561	Loss
CAMK_RAD53_CHEK2_ST	P04637	TP53	O96017	CHEK2	S269	V274I	274	Missense	distal	5	no	12.111	12.072	EPSD	COSMIC	8.561	Down-regulation
CAMK_RAD53_CHEK2_ST	P04637	TP53	O96017	CHEK2	S269	L265M	265	Missense	distal	-4	no	12.111	11.953	EPSD	COSMIC	8.561	Down-regulation
CAMK_RAD53_CHEK2_ST	P04637	TP53	O96017	CHEK2	S269	F270Y	270	Missense	proximal	1	no	12.111	8.796	EPSD	COSMIC	8.561	Down-regulation
CAMK_RAD53_CHEK2_ST	P04637	TP53	O96017	CHEK2	S269	L264V	264	Missense	distal	-5	no	12.111	11.588	EPSD	COSMIC	8.561	Down-regulation
CAMK_RAD53_CHEK2_ST	P04637	TP53	O96017	CHEK2	S269	S269G	269	Missense	central	0	yes	12.111	0.000	EPSD	COSMIC	8.561	Loss
CAMK_RAD53_CHEK2_ST	P04637	TP53	O96017	CHEK2	S269	R273Q	273	Missense	distal	4	no	12.111	12.174	EPSD	COSMIC	8.561	Up-regulation
CAMK_RAD53_CHEK2_ST	P04637	TP53	O96017	CHEK2	S269	N268H	268	Missense	proximal	-1	no	12.111	11.571	EPSD	COSMIC	8.561	Down-regulation
CAMK_RAD53_CHEK2_ST	P04637	TP53	O96017	CHEK2	S269	G262D	262	Missense	distal	-7	no	12.111	10.598	EPSD	COSMIC;GDSC;CCLE	8.561	Down-regulation
CAMK_RAD53_CHEK2_ST	P04637	TP53	O96017	CHEK2	S269	N263I	263	Missense	distal	-6	no	12.111	11.931	EPSD	COSMIC	8.561	Down-regulation
CAMK_RAD53_CHEK2_ST	P04637	TP53	O96017	CHEK2	S269	L264P	264	Missense	distal	-5	no	12.111	12.322	EPSD	COSMIC	8.561	Up-regulation
CAMK_RAD53_CHEK2_ST	P04637	TP53	O96017	CHEK2	S269	E271P	271	Missense	proximal	2	no	12.111	12.183	EPSD	COSMIC	8.561	Up-regulation
CAMK_RAD53_CHEK2_ST	P04637	TP53	O96017	CHEK2	S269	L264R	264	Missense	distal	-5	no	12.111	12.057	EPSD	COSMIC;GDSC;CCLE	8.561	Down-regulation
CAMK_RAD53_CHEK2_ST	P04637	TP53	O96017	CHEK2	S269	R273Y	273	Missense	distal	4	no	12.111	12.954	EPSD	COSMIC;CCLE	8.561	Up-regulation
CAMK_RAD53_CHEK2_ST	P04637	TP53	O96017	CHEK2	S269	N263D	263	Missense	distal	-6	no	12.111	11.921	EPSD	COSMIC	8.561	Down-regulation
CAMK_RAD53_CHEK2_ST	P04637	TP53	O96017	CHEK2	S269	A276T	276	Missense	distal	7	no	12.111	12.113	EPSD	COSMIC	8.561	Up-regulation
CAMK_RAD53_CHEK2_ST	P04637	TP53	O96017	CHEK2	S269	S269C	269	Missense	central	0	yes	12.111	0.000	EPSD	COSMIC	8.561	Loss
CAMK_RAD53_CHEK2_ST	P04637	TP53	O96017	CHEK2	S269	L264I	264	Missense	distal	-5	no	12.111	11.795	EPSD	COSMIC	8.561	Down-regulation
CAMK_RAD53_CHEK2_ST	P04637	TP53	O96017	CHEK2	S269	N268K	268	Missense	proximal	-1	no	12.111	11.845	EPSD	COSMIC	8.561	Down-regulation
CAMK_RAD53_CHEK2_ST	P04637	TP53	O96017	CHEK2	S269	A276F	276	Missense	distal	7	no	12.111	12.139	EPSD	COSMIC	8.561	Up-regulation
CAMK_RAD53_CHEK2_ST	P04637	TP53	O96017	CHEK2	S269	G266T	266	Missense	distal	-3	no	12.111	9.474	EPSD	COSMIC	8.561	Down-regulation
CAMK_RAD53_CHEK2_ST	P04637	TP53	O96017	CHEK2	S269	G266K	266	Missense	distal	-3	no	12.111	12.932	EPSD	COSMIC	8.561	Up-regulation
CAMK_RAD53_CHEK2_ST	P04637	TP53	O96017	CHEK2	S269	E271G	271	Missense	proximal	2	no	12.111	12.171	EPSD	COSMIC	8.561	Up-regulation
CAMK_RAD53_CHEK2_ST	P04637	TP53	O96017	CHEK2	S269	L264Q	264	Missense	distal	-5	no	12.111	12.180	EPSD	COSMIC	8.561	Up-regulation
CAMK_RAD53_CHEK2_ST	P04637	TP53	O96017	CHEK2	S269	S269I	269	Missense	central	0	yes	12.111	0.000	EPSD	COSMIC	8.561	Loss
CAMK_RAD53_CHEK2_ST	P04637	TP53	O96017	CHEK2	S269	S269R	269	Missense	central	0	yes	12.111	0.000	EPSD	COSMIC	8.561	Loss
CAMK_RAD53_CHEK2_ST	P04637	TP53	O96017	CHEK2	S269	G262R	262	Missense	distal	-7	no	12.111	12.180	EPSD	COSMIC	8.561	Up-regulation
CAMK_RAD53_CHEK2_ST	P04637	TP53	O96017	CHEK2	S269	N263K	263	Missense	distal	-6	no	12.111	12.341	EPSD	COSMIC	8.561	Up-regulation
CAMK_RAD53_CHEK2_ST	P04637	TP53	O96017	CHEK2	S269	V272K	272	Missense	distal	3	no	12.111	12.159	EPSD	COSMIC	8.561	Up-regulation
CAMK_RAD53_CHEK2_ST	P04637	TP53	O96017	CHEK2	S269	N268F	268	Missense	proximal	-1	no	12.111	12.024	EPSD	COSMIC	8.561	Down-regulation
CAMK_RAD53_CHEK2_ST	P04637	TP53	O96017	CHEK2	S269	L265Q	265	Missense	distal	-4	no	12.111	13.571	EPSD	COSMIC	8.561	Up-regulation
CAMK_RAD53_CHEK2_ST	P04637	TP53	O96017	CHEK2	S269	N268S	268	Missense	proximal	-1	no	12.111	11.624	EPSD	COSMIC	8.561	Down-regulation
CAMK_RAD53_CHEK2_ST	P04637	TP53	O96017	CHEK2	S269	G262S	262	Missense	distal	-7	no	12.111	12.583	EPSD	COSMIC;GDSC	8.561	Up-regulation
CAMK_RAD53_CHEK2_ST	P04637	TP53	O96017	CHEK2	S269	G266S	266	Missense	distal	-3	no	12.111	11.159	EPSD	COSMIC	8.561	Down-regulation
CAMK_RAD53_CHEK2_ST	P04637	TP53	O96017	CHEK2	T284	D281R	281	Missense	distal	-3	no	0.848	10.088	EPSD	COSMIC	8.561	Gain
CAMK_RAD53_CHEK2_ST	P04637	TP53	O96017	CHEK2	T312	P309R	309	Missense	distal	-3	no	5.245	10.971	EPSD	COSMIC	8.561	Gain
CAMK_RAD53_CHEK2_ST	P04637	TP53	O96017	CHEK2	S362	E358Q	358	Missense	distal	-4	no	7.920	9.035	EPSD	COSMIC	8.561	Gain
CAMK_RAD53_CHEK2_ST	P04637	TP53	O96017	CHEK2	S362	E358K	358	Missense	distal	-4	no	7.920	9.057	EPSD	COSMIC	8.561	Gain
CAMK_RAD53_CHEK2_ST	P04637	TP53	O96017	CHEK2	S366	S367F	367	Missense	proximal	1	no	12.323	17.079	PhosphoSitePlus;EPSD	COSMIC	8.561	Up-regulation
CAMK_RAD53_CHEK2_ST	P04637	TP53	O96017	CHEK2	S366	K370N	370	Missense	distal	4	no	12.323	12.453	PhosphoSitePlus;EPSD	COSMIC	8.561	Up-regulation
CAMK_RAD53_CHEK2_ST	P04637	TP53	O96017	CHEK2	S366	G361E	361	Missense	distal	-5	no	12.323	12.532	PhosphoSitePlus;EPSD	COSMIC	8.561	Up-regulation
CAMK_RAD53_CHEK2_ST	P04637	TP53	O96017	CHEK2	S366	P359S	359	Missense	distal	-7	no	12.323	12.560	PhosphoSitePlus;EPSD	COSMIC	8.561	Up-regulation
CAMK_RAD53_CHEK2_ST	P04637	TP53	O96017	CHEK2	S366	A364D	364	Missense	proximal	-2	no	12.323	11.464	PhosphoSitePlus;EPSD	COSMIC	8.561	Down-regulation
CAMK_RAD53_CHEK2_ST	P04637	TP53	O96017	CHEK2	S366	H365Y	365	Missense	proximal	-1	no	12.323	12.923	PhosphoSitePlus;EPSD	COSMIC	8.561	Up-regulation
CAMK_RAD53_CHEK2_ST	P04637	TP53	O96017	CHEK2	S366	G360A	360	Missense	distal	-6	no	12.323	12.366	PhosphoSitePlus;EPSD	COSMIC	8.561	Up-regulation
CAMK_RAD53_CHEK2_ST	P04637	TP53	O96017	CHEK2	S366	A364T	364	Missense	proximal	-2	no	12.323	12.178	PhosphoSitePlus;EPSD	COSMIC	8.561	Down-regulation
CAMK_RAD53_CHEK2_ST	P04637	TP53	O96017	CHEK2	S366	S366A	366	Missense	central	0	yes	12.323	0.000	PhosphoSitePlus;EPSD	COSMIC	8.561	Loss
CAMK_RAD53_CHEK2_ST	P04637	TP53	O96017	CHEK2	S366	G361R	361	Missense	distal	-5	no	12.323	13.292	PhosphoSitePlus;EPSD	COSMIC	8.561	Up-regulation
CAMK_RAD53_CHEK2_ST	P04637	TP53	O96017	CHEK2	S366	K370Q	370	Missense	distal	4	no	12.323	11.974	PhosphoSitePlus;EPSD	COSMIC	8.561	Down-regulation
CAMK_RAD53_CHEK2_ST	P04637	TP53	O96017	CHEK2	S366	K373R	373	Missense	distal	7	no	12.323	12.320	PhosphoSitePlus;EPSD	COSMIC	8.561	Down-regulation
CAMK_RAD53_CHEK2_ST	P04637	TP53	O96017	CHEK2	S366	S371P	371	Missense	distal	5	no	12.323	12.192	PhosphoSitePlus;EPSD	COSMIC	8.561	Down-regulation
CAMK_RAD53_CHEK2_ST	P04637	TP53	O96017	CHEK2	S371	S367F	367	Missense	distal	-4	no	9.892	7.010	EPSD	COSMIC	8.561	Loss
CAMK_RAD53_CHEK2_ST	P04637	TP53	O96017	CHEK2	S371	K370N	370	Missense	proximal	-1	no	9.892	10.157	EPSD	COSMIC	8.561	Up-regulation
CAMK_RAD53_CHEK2_ST	P04637	TP53	O96017	CHEK2	S371	A364D	364	Missense	distal	-7	no	9.892	8.971	EPSD	COSMIC	8.561	Down-regulation
CAMK_RAD53_CHEK2_ST	P04637	TP53	O96017	CHEK2	S371	H365Y	365	Missense	distal	-6	no	9.892	9.386	EPSD	COSMIC	8.561	Down-regulation
CAMK_RAD53_CHEK2_ST	P04637	TP53	O96017	CHEK2	S371	A364T	364	Missense	distal	-7	no	9.892	10.109	EPSD	COSMIC	8.561	Up-regulation
CAMK_RAD53_CHEK2_ST	P04637	TP53	O96017	CHEK2	S371	S376T	376	Missense	distal	5	no	9.892	9.868	EPSD	COSMIC	8.561	Down-regulation
CAMK_RAD53_CHEK2_ST	P04637	TP53	O96017	CHEK2	S371	S366A	366	Missense	distal	-5	no	9.892	9.793	EPSD	COSMIC	8.561	Down-regulation
CAMK_RAD53_CHEK2_ST	P04637	TP53	O96017	CHEK2	S371	T377I	377	Missense	distal	6	no	9.892	9.416	EPSD	COSMIC	8.561	Down-regulation
CAMK_RAD53_CHEK2_ST	P04637	TP53	O96017	CHEK2	S371	S378F	378	Missense	distal	7	no	9.892	9.932	EPSD	COSMIC	8.561	Up-regulation
CAMK_RAD53_CHEK2_ST	P04637	TP53	O96017	CHEK2	S371	K370Q	370	Missense	proximal	-1	no	9.892	9.383	EPSD	COSMIC	8.561	Down-regulation
CAMK_RAD53_CHEK2_ST	P04637	TP53	O96017	CHEK2	S371	K373R	373	Missense	proximal	2	no	9.892	9.947	EPSD	COSMIC	8.561	Up-regulation
CAMK_RAD53_CHEK2_ST	P04637	TP53	O96017	CHEK2	S371	S376F	376	Missense	distal	5	no	9.892	9.503	EPSD	COSMIC	8.561	Down-regulation
CAMK_RAD53_CHEK2_ST	P04637	TP53	O96017	CHEK2	S371	G374S	374	Missense	distal	3	no	9.892	9.191	EPSD	COSMIC	8.561	Down-regulation
CAMK_RAD53_CHEK2_ST	P04637	TP53	O96017	CHEK2	S371	S376A	376	Missense	distal	5	no	9.892	9.869	EPSD	COSMIC	8.561	Down-regulation
CAMK_RAD53_CHEK2_ST	P04637	TP53	O96017	CHEK2	S371	S371P	371	Missense	central	0	yes	9.892	0.000	EPSD	COSMIC	8.561	Loss
CAMK_RAD53_CHEK2_ST	P04637	TP53	O96017	CHEK2	S376	K373R	373	Missense	distal	-3	no	6.259	11.343	EPSD	COSMIC	8.561	Gain
CAMK_RAD53_CHEK2_ST	P04637	TP53	O96017	CHEK2	T377	S378F	378	Missense	proximal	1	no	7.326	12.082	EPSD	COSMIC	8.561	Gain
CAMK_RAD53_CHEK2_ST	O00716	E2F3	O96017	CHEK2	S124	G120D	120	Missense	distal	-4	no	13.499	12.361	PhosphoSitePlus	COSMIC	8.561	Down-regulation
CAMK_RAD53_CHEK2_ST	O00716	E2F3	O96017	CHEK2	S163	P167A	167	Missense	distal	4	no	10.585	10.762	EPSD	COSMIC	8.561	Up-regulation
CAMK_RAD53_CHEK2_ST	O00716	E2F3	O96017	CHEK2	S163	P170T	170	Missense	distal	7	no	10.585	10.589	EPSD	COSMIC	8.561	Up-regulation
CAMK_RAD53_CHEK2_ST	O00716	E2F3	O96017	CHEK2	S163	A159S	159	Missense	distal	-4	no	10.585	10.744	EPSD	COSMIC	8.561	Up-regulation
CAMK_RAD53_CHEK2_ST	O00716	E2F3	O96017	CHEK2	S163	D165H	165	Missense	proximal	2	no	10.585	10.892	EPSD	COSMIC	8.561	Up-regulation
CAMK_RAD53_CHEK2_ST	O00716	E2F3	O96017	CHEK2	S174	E175Q	175	Missense	proximal	1	no	6.175	10.697	EPSD	COSMIC	8.561	Gain
CAMK_RAD53_CHEK2_ST	O00716	E2F3	O96017	CHEK2	T181	T177S	177	Missense	distal	-4	no	10.130	11.069	EPSD	COSMIC	8.561	Up-regulation
CAMK_RAD53_CHEK2_ST	O00716	E2F3	O96017	CHEK2	T181	E175Q	175	Missense	distal	-6	no	10.130	10.221	EPSD	COSMIC	8.561	Up-regulation
CAMK_RAD53_CHEK2_ST	O00716	E2F3	O96017	CHEK2	T181	K176N	176	Missense	distal	-5	no	10.130	9.646	EPSD	COSMIC	8.561	Down-regulation
CAMK_RAD53_CHEK2_ST	O00716	E2F3	O96017	CHEK2	T181	T181A	181	Missense	central	0	yes	10.130	0.000	EPSD	COSMIC	8.561	Loss
CAMK_RAD53_CHEK2_ST	O00716	E2F3	O96017	CHEK2	T181	L183V	183	Missense	proximal	2	no	10.130	10.174	EPSD	COSMIC	8.561	Up-regulation
CAMK_RAD53_CHEK2_ST	O00716	E2F3	O96017	CHEK2	T181	T177M	177	Missense	distal	-4	no	10.130	9.426	EPSD	COSMIC	8.561	Down-regulation
CAMK_RAD53_CHEK2_ST	O00716	E2F3	O96017	CHEK2	T181	L183F	183	Missense	proximal	2	no	10.130	9.634	EPSD	COSMIC	8.561	Down-regulation
CAMK_RAD53_CHEK2_ST	O00716	E2F3	O96017	CHEK2	T181	Y179C	179	Missense	proximal	-2	no	10.130	11.023	EPSD	COSMIC	8.561	Up-regulation
CAMK_RAD53_CHEK2_ST	O00716	E2F3	O96017	CHEK2	S308	D312E	312	Missense	distal	4	no	10.470	9.834	EPSD	COSMIC	8.561	Down-regulation
CAMK_RAD53_CHEK2_ST	O00716	E2F3	O96017	CHEK2	S308	Q302E	302	Missense	distal	-6	no	10.470	10.379	EPSD	COSMIC	8.561	Down-regulation
CAMK_RAD53_CHEK2_ST	O00716	E2F3	O96017	CHEK2	S308	S308N	308	Missense	central	0	yes	10.470	0.000	EPSD	COSMIC	8.561	Loss
CAMK_RAD53_CHEK2_ST	O43255	SIAH2	O96017	CHEK2	S5	S2R	2	Missense	distal	-3	no	2.628	9.485	EPSD	COSMIC	8.561	Gain
CAMK_RAD53_CHEK2_ST	O43255	SIAH2	O96017	CHEK2	S6	S2R	2	Missense	distal	-4	no	10.667	10.543	EPSD	COSMIC	8.561	Down-regulation
CAMK_RAD53_CHEK2_ST	O43255	SIAH2	O96017	CHEK2	T26	S28F	28	Missense	proximal	2	no	10.757	10.013	EPSD;PhosphoSitePlus	COSMIC	8.561	Down-regulation
CAMK_RAD53_CHEK2_ST	O43255	SIAH2	O96017	CHEK2	T26	P27R	27	Missense	proximal	1	no	10.757	9.689	EPSD;PhosphoSitePlus	COSMIC	8.561	Down-regulation
CAMK_RAD53_CHEK2_ST	O43255	SIAH2	O96017	CHEK2	S28	S28F	28	Missense	central	0	yes	10.729	0.000	EPSD;PhosphoSitePlus	COSMIC	8.561	Loss
CAMK_RAD53_CHEK2_ST	O43255	SIAH2	O96017	CHEK2	S28	P27R	27	Missense	proximal	-1	no	10.729	10.601	EPSD;PhosphoSitePlus	COSMIC	8.561	Down-regulation
CAMK_RAD53_CHEK2_ST	O96017	CHEK2	O96017	CHEK2	S19	H13Y	13	Missense	distal	-6	no	9.661	9.155	EPSD;PhosphoSitePlus	COSMIC	8.561	Down-regulation
CAMK_RAD53_CHEK2_ST	O96017	CHEK2	O96017	CHEK2	S19	V25I	25	Missense	distal	6	no	9.661	9.510	EPSD;PhosphoSitePlus	COSMIC	8.561	Down-regulation
CAMK_RAD53_CHEK2_ST	O96017	CHEK2	O96017	CHEK2	S19	H13N	13	Missense	distal	-6	no	9.661	9.382	EPSD;PhosphoSitePlus	COSMIC	8.561	Down-regulation
CAMK_RAD53_CHEK2_ST	O96017	CHEK2	O96017	CHEK2	S19	S19L	19	Missense	central	0	yes	9.661	0.000	EPSD;PhosphoSitePlus	COSMIC	8.561	Loss
CAMK_RAD53_CHEK2_ST	O96017	CHEK2	O96017	CHEK2	T26	V25I	25	Missense	proximal	-1	no	12.425	12.519	EPSD	COSMIC	8.561	Up-regulation
CAMK_RAD53_CHEK2_ST	O96017	CHEK2	O96017	CHEK2	T26	S19L	19	Missense	distal	-7	no	12.425	11.479	EPSD	COSMIC	8.561	Down-regulation
CAMK_RAD53_CHEK2_ST	O96017	CHEK2	O96017	CHEK2	S44	M46T	46	Missense	proximal	2	no	8.832	8.994	EPSD	COSMIC	8.561	Up-regulation
CAMK_RAD53_CHEK2_ST	O96017	CHEK2	O96017	CHEK2	S44	S49C	49	Missense	distal	5	no	8.832	8.716	EPSD	COSMIC	8.561	Down-regulation
CAMK_RAD53_CHEK2_ST	O96017	CHEK2	O96017	CHEK2	S44	S50N	50	Missense	distal	6	no	8.832	8.328	EPSD	COSMIC	8.561	Loss
CAMK_RAD53_CHEK2_ST	O96017	CHEK2	O96017	CHEK2	S44	S50T	50	Missense	distal	6	no	8.832	8.838	EPSD	COSMIC	8.561	Up-regulation
CAMK_RAD53_CHEK2_ST	O96017	CHEK2	O96017	CHEK2	S50	M46T	46	Missense	distal	-4	no	9.393	10.097	EPSD	COSMIC	8.561	Up-regulation
CAMK_RAD53_CHEK2_ST	O96017	CHEK2	O96017	CHEK2	S50	S52P	52	Missense	proximal	2	no	9.393	9.341	EPSD	COSMIC;GDSC;CCLE	8.561	Down-regulation
CAMK_RAD53_CHEK2_ST	O96017	CHEK2	O96017	CHEK2	S50	S49C	49	Missense	proximal	-1	no	9.393	9.581	EPSD	COSMIC	8.561	Up-regulation
CAMK_RAD53_CHEK2_ST	O96017	CHEK2	O96017	CHEK2	S50	S50N	50	Missense	central	0	yes	9.393	0.000	EPSD	COSMIC	8.561	Loss
CAMK_RAD53_CHEK2_ST	O96017	CHEK2	O96017	CHEK2	T68	Q69R	69	Missense	proximal	1	no	9.703	6.108	EPSD;PhosphoSitePlus	COSMIC	8.561	Loss
CAMK_RAD53_CHEK2_ST	O96017	CHEK2	O96017	CHEK2	S120	F125V	125	Missense	distal	5	no	8.749	8.985	EPSD;PhosphoSitePlus	COSMIC	8.561	Up-regulation
CAMK_RAD53_CHEK2_ST	O96017	CHEK2	O96017	CHEK2	S120	S120C	120	Missense	central	0	yes	8.749	0.000	EPSD;PhosphoSitePlus	COSMIC	8.561	Loss
CAMK_RAD53_CHEK2_ST	O96017	CHEK2	O96017	CHEK2	S120	C124Y	124	Missense	distal	4	no	8.749	9.186	EPSD;PhosphoSitePlus	COSMIC	8.561	Up-regulation
CAMK_RAD53_CHEK2_ST	O96017	CHEK2	O96017	CHEK2	S120	R117G	117	Missense	distal	-3	no	8.749	2.843	EPSD;PhosphoSitePlus	COSMIC	8.561	Loss
CAMK_RAD53_CHEK2_ST	O96017	CHEK2	O96017	CHEK2	S120	R117M	117	Missense	distal	-3	no	8.749	1.548	EPSD;PhosphoSitePlus	COSMIC	8.561	Loss
CAMK_RAD53_CHEK2_ST	O96017	CHEK2	O96017	CHEK2	S140	T133K	133	Missense	distal	-7	no	11.986	12.163	EPSD;PhosphoSitePlus	COSMIC	8.561	Up-regulation
CAMK_RAD53_CHEK2_ST	O96017	CHEK2	O96017	CHEK2	S140	R137Q	137	Missense	distal	-3	no	11.986	2.037	EPSD;PhosphoSitePlus	COSMIC	8.561	Loss
CAMK_RAD53_CHEK2_ST	O96017	CHEK2	O96017	CHEK2	S140	R145L	145	Missense	distal	5	no	11.986	11.729	EPSD;PhosphoSitePlus	COSMIC	8.561	Down-regulation
CAMK_RAD53_CHEK2_ST	O96017	CHEK2	O96017	CHEK2	S140	F144L	144	Missense	distal	4	no	11.986	11.314	EPSD;PhosphoSitePlus	COSMIC	8.561	Down-regulation
CAMK_RAD53_CHEK2_ST	O96017	CHEK2	O96017	CHEK2	T383	Y390C	390	Missense	distal	7	no	10.620	10.598	EPSD;PhosphoSitePlus	COSMIC	8.561	Down-regulation
CAMK_RAD53_CHEK2_ST	O96017	CHEK2	O96017	CHEK2	T383	M381I	381	Missense	proximal	-2	no	10.620	10.824	EPSD;PhosphoSitePlus	COSMIC	8.561	Up-regulation
CAMK_RAD53_CHEK2_ST	O96017	CHEK2	O96017	CHEK2	T383	M381V	381	Missense	proximal	-2	no	10.620	10.810	EPSD;PhosphoSitePlus	COSMIC	8.561	Up-regulation
CAMK_RAD53_CHEK2_ST	O96017	CHEK2	O96017	CHEK2	T383	S379C	379	Missense	distal	-4	no	10.620	9.491	EPSD;PhosphoSitePlus	COSMIC	8.561	Down-regulation
CAMK_RAD53_CHEK2_ST	O96017	CHEK2	O96017	CHEK2	T383	Y390D	390	Missense	distal	7	no	10.620	10.612	EPSD;PhosphoSitePlus	COSMIC	8.561	Down-regulation
CAMK_RAD53_CHEK2_ST	O96017	CHEK2	O96017	CHEK2	T387	Y390D	390	Missense	distal	3	no	8.388	8.630	EPSD;PhosphoSitePlus	COSMIC	8.561	Gain
CAMK_RAD53_CHEK2_ST	O96017	CHEK2	O96017	CHEK2	T389	Y390C	390	Missense	proximal	1	no	9.292	9.603	EPSD	COSMIC	8.561	Up-regulation
CAMK_RAD53_CHEK2_ST	O96017	CHEK2	O96017	CHEK2	T389	E394K	394	Missense	distal	5	no	9.292	9.325	EPSD	COSMIC;CCLE	8.561	Up-regulation
CAMK_RAD53_CHEK2_ST	O96017	CHEK2	O96017	CHEK2	T389	A392S	392	Missense	distal	3	no	9.292	9.301	EPSD	COSMIC	8.561	Up-regulation
CAMK_RAD53_CHEK2_ST	O96017	CHEK2	O96017	CHEK2	T389	P393L	393	Missense	distal	4	no	9.292	9.384	EPSD	COSMIC	8.561	Up-regulation
CAMK_RAD53_CHEK2_ST	O96017	CHEK2	O96017	CHEK2	T389	V395L	395	Missense	distal	6	no	9.292	9.542	EPSD	COSMIC	8.561	Up-regulation
CAMK_RAD53_CHEK2_ST	O96017	CHEK2	O96017	CHEK2	T389	Y390D	390	Missense	proximal	1	no	9.292	8.408	EPSD	COSMIC	8.561	Loss
CAMK_RAD53_CHEK2_ST	O96017	CHEK2	O96017	CHEK2	T432	P426L	426	Missense	distal	-6	no	8.836	8.636	EPSD;PhosphoSitePlus	COSMIC	8.561	Down-regulation
CAMK_RAD53_CHEK2_ST	O96017	CHEK2	O96017	CHEK2	T432	K437Q	437	Missense	distal	5	no	8.836	8.897	EPSD;PhosphoSitePlus	COSMIC	8.561	Up-regulation
CAMK_RAD53_CHEK2_ST	O96017	CHEK2	O96017	CHEK2	S435	K437Q	437	Missense	proximal	2	no	10.217	10.068	EPSD;PhosphoSitePlus	COSMIC	8.561	Down-regulation
CAMK_RAD53_CHEK2_ST	O96017	CHEK2	O96017	CHEK2	S435	T441I	441	Missense	distal	6	no	10.217	9.741	EPSD;PhosphoSitePlus	COSMIC	8.561	Down-regulation
CAMK_RAD53_CHEK2_ST	O96017	CHEK2	O96017	CHEK2	S516	R519Q	519	Missense	distal	3	no	9.518	9.126	EPSD;PhosphoSitePlus	COSMIC	8.561	Down-regulation
CAMK_RAD53_CHEK2_ST	O96017	CHEK2	O96017	CHEK2	S516	R523P	523	Missense	distal	7	no	9.518	9.525	EPSD;PhosphoSitePlus	COSMIC	8.561	Up-regulation
CAMK_RAD53_CHEK2_ST	O96017	CHEK2	O96017	CHEK2	S516	R519G	519	Missense	distal	3	no	9.518	10.317	EPSD;PhosphoSitePlus	COSMIC	8.561	Up-regulation
CAMK_RAD53_CHEK2_ST	O96017	CHEK2	O96017	CHEK2	S516	R523H	523	Missense	distal	7	no	9.518	9.524	EPSD;PhosphoSitePlus	COSMIC	8.561	Up-regulation
CAMK_RAD53_CHEK2_ST	O96017	CHEK2	O96017	CHEK2	S516	Q510H	510	Missense	distal	-6	no	9.518	9.578	EPSD;PhosphoSitePlus	COSMIC	8.561	Up-regulation
CAMK_RAD53_CHEK2_ST	O96017	CHEK2	O96017	CHEK2	S518	R519Q	519	Missense	proximal	1	no	6.973	10.568	EPSD	COSMIC	8.561	Gain
CAMK_RAD53_CHEK2_ST	P33981	TTK	O96017	CHEK2	S214	V208A	208	Missense	distal	-6	no	11.199	11.404	EPSD	COSMIC	8.561	Up-regulation
CAMK_RAD53_CHEK2_ST	P33981	TTK	O96017	CHEK2	T424	T418K	418	Missense	distal	-6	no	9.452	9.517	EPSD	COSMIC	8.561	Up-regulation
CAMK_RAD53_CHEK2_ST	P33981	TTK	O96017	CHEK2	S440	T441I	441	Missense	proximal	1	no	10.146	9.164	EPSD	COSMIC	8.561	Down-regulation
CAMK_RAD53_CHEK2_ST	P33981	TTK	O96017	CHEK2	T458	S455N	455	Missense	distal	-3	no	10.008	8.168	EPSD	COSMIC;GDSC	8.561	Loss
CAMK_RAD53_CHEK2_ST	P33981	TTK	O96017	CHEK2	T458	T458A	458	Missense	central	0	yes	10.008	0.000	EPSD	COSMIC	8.561	Loss
CAMK_RAD53_CHEK2_ST	P33981	TTK	O96017	CHEK2	T458	C465F	465	Missense	distal	7	no	10.008	10.032	EPSD	COSMIC	8.561	Up-regulation
CAMK_RAD53_CHEK2_ST	P33981	TTK	O96017	CHEK2	T458	K452N	452	Missense	distal	-6	no	10.008	9.778	EPSD	COSMIC	8.561	Down-regulation
CAMK_RAD53_CHEK2_ST	P33981	TTK	O96017	CHEK2	T458	K452E	452	Missense	distal	-6	no	10.008	9.905	EPSD	COSMIC	8.561	Down-regulation
CAMK_RAD53_CHEK2_ST	P33981	TTK	O96017	CHEK2	T458	M463T	463	Missense	distal	5	no	10.008	10.193	EPSD	COSMIC	8.561	Up-regulation
CAMK_RAD53_CHEK2_ST	P33981	TTK	O96017	CHEK2	T458	S455R	455	Missense	distal	-3	no	10.008	16.865	EPSD	COSMIC	8.561	Up-regulation
CAMK_RAD53_CHEK2_ST	P33981	TTK	O96017	CHEK2	T458	S455I	455	Missense	distal	-3	no	10.008	7.398	EPSD	COSMIC	8.561	Loss
CAMK_RAD53_CHEK2_ST	P33981	TTK	O96017	CHEK2	S526	Y525H	525	Missense	proximal	-1	no	10.853	10.253	EPSD	COSMIC	8.561	Down-regulation
CAMK_RAD53_CHEK2_ST	P33981	TTK	O96017	CHEK2	S526	Q530K	530	Missense	distal	4	no	10.853	11.202	EPSD	COSMIC	8.561	Up-regulation
CAMK_RAD53_CHEK2_ST	P33981	TTK	O96017	CHEK2	S526	V520L	520	Missense	distal	-6	no	10.853	10.959	EPSD	COSMIC	8.561	Up-regulation
CAMK_RAD53_CHEK2_ST	P33981	TTK	O96017	CHEK2	T831	A828V	828	Missense	distal	-3	no	10.742	7.011	EPSD	COSMIC	8.561	Loss
CAMK_RAD53_CHEK2_ST	P33981	TTK	O96017	CHEK2	S845	N843I	843	Missense	proximal	-2	no	8.522	8.647	EPSD	COSMIC	8.561	Gain
CAMK_RAD53_CHEK2_ST	P33981	TTK	O96017	CHEK2	T849	K856N	856	Missense	distal	7	no	9.416	9.428	EPSD	COSMIC	8.561	Up-regulation
CAMK_RAD53_CHEK2_ST	P33981	TTK	O96017	CHEK2	T849	G855R	855	Missense	distal	6	no	9.416	9.709	EPSD	COSMIC;GDSC	8.561	Up-regulation
CAMK_RAD53_CHEK2_ST	P33981	TTK	O96017	CHEK2	T849	G855E	855	Missense	distal	6	no	9.416	9.356	EPSD	COSMIC;CCLE	8.561	Down-regulation
CAMK_RAD53_CHEK2_ST	P33981	TTK	O96017	CHEK2	T849	K848R	848	Missense	proximal	-1	no	9.416	8.888	EPSD	COSMIC	8.561	Down-regulation
CAMK_RAD53_CHEK2_ST	P33981	TTK	O96017	CHEK2	T849	K853Q	853	Missense	distal	4	no	9.416	9.067	EPSD	COSMIC	8.561	Down-regulation
CAMK_RAD53_CHEK2_ST	P33981	TTK	O96017	CHEK2	T849	N843I	843	Missense	distal	-6	no	9.416	9.237	EPSD	COSMIC	8.561	Down-regulation
CAMK_RAD53_CHEK2_ST	P33981	TTK	O96017	CHEK2	T849	K852Q	852	Missense	distal	3	no	9.416	8.223	EPSD	COSMIC	8.561	Loss
CAMK_RAD53_CHEK2_ST	Q08050	FOXM1	O96017	CHEK2	S306	V305L	305	Missense	proximal	-1	no	8.861	8.263	EPSD	COSMIC	8.561	Loss
CAMK_RAD53_CHEK2_ST	Q08050	FOXM1	O96017	CHEK2	T319	F324L	324	Missense	distal	5	no	10.462	10.653	EPSD	COSMIC;GDSC;CCLE	8.561	Up-regulation
CAMK_RAD53_CHEK2_ST	Q08050	FOXM1	O96017	CHEK2	S340	R344Q	344	Missense	distal	4	no	9.446	9.510	EPSD	COSMIC	8.561	Up-regulation
CAMK_RAD53_CHEK2_ST	Q08050	FOXM1	O96017	CHEK2	T354	R350Q	350	Missense	distal	-4	no	15.248	15.346	EPSD	COSMIC	8.561	Up-regulation
CAMK_RAD53_CHEK2_ST	Q08050	FOXM1	O96017	CHEK2	T354	R350L	350	Missense	distal	-4	no	15.248	13.886	EPSD	COSMIC	8.561	Down-regulation
CAMK_RAD53_CHEK2_ST	Q08050	FOXM1	O96017	CHEK2	S376	R373L	373	Missense	distal	-3	no	12.514	4.903	EPSD	COSMIC	8.561	Loss
CAMK_RAD53_CHEK2_ST	Q08050	FOXM1	O96017	CHEK2	S516	R521M	521	Missense	distal	5	no	8.646	8.377	EPSD	COSMIC	8.561	Loss
CAMK_RAD53_CHEK2_ST	Q08050	FOXM1	O96017	CHEK2	S516	S518I	518	Missense	proximal	2	no	8.646	8.354	EPSD	COSMIC	8.561	Loss
CAMK_RAD53_CHEK2_ST	Q08050	FOXM1	O96017	CHEK2	S516	T510N	510	Missense	distal	-6	no	8.646	8.481	EPSD	COSMIC;CCLE	8.561	Loss
CAMK_RAD53_CHEK2_ST	Q08050	FOXM1	O96017	CHEK2	S522	R525W	525	Missense	distal	3	no	7.718	9.111	EPSD	COSMIC	8.561	Gain
CAMK_RAD53_CHEK2_ST	Q08050	FOXM1	O96017	CHEK2	T524	R521M	521	Missense	distal	-3	no	10.662	3.461	EPSD	COSMIC	8.561	Loss
CAMK_RAD53_CHEK2_ST	Q08050	FOXM1	O96017	CHEK2	T524	S518I	518	Missense	distal	-6	no	10.662	10.114	EPSD	COSMIC	8.561	Down-regulation
CAMK_RAD53_CHEK2_ST	Q08050	FOXM1	O96017	CHEK2	T524	V527A	527	Missense	distal	3	no	10.662	9.997	EPSD	COSMIC	8.561	Down-regulation
CAMK_RAD53_CHEK2_ST	Q08050	FOXM1	O96017	CHEK2	T524	R525W	525	Missense	proximal	1	no	10.662	9.783	EPSD	COSMIC	8.561	Down-regulation
CAMK_RAD53_CHEK2_ST	Q08050	FOXM1	O96017	CHEK2	T524	C526S	526	Missense	proximal	2	no	10.662	10.884	EPSD	COSMIC	8.561	Up-regulation
CAMK_RAD53_CHEK2_ST	Q08050	FOXM1	O96017	CHEK2	S581	S582F	582	Missense	proximal	1	no	4.556	9.312	EPSD	COSMIC	8.561	Gain
CAMK_RAD53_CHEK2_ST	Q08050	FOXM1	O96017	CHEK2	T620	P621L	621	Missense	proximal	1	no	8.228	9.518	EPSD	COSMIC	8.561	Gain
CAMK_RAD53_CHEK2_ST	Q08050	FOXM1	O96017	CHEK2	S678	P673S	673	Missense	distal	-5	no	13.451	12.891	EPSD	COSMIC	8.561	Down-regulation
CAMK_RAD53_CHEK2_ST	Q08050	FOXM1	O96017	CHEK2	S678	R675K	675	Missense	distal	-3	no	13.451	8.366	EPSD	COSMIC	8.561	Loss
CAMK_RAD53_CHEK2_ST	Q08050	FOXM1	O96017	CHEK2	S717	G721S	721	Missense	distal	4	no	10.780	10.091	EPSD	COSMIC	8.561	Down-regulation
CAMK_RAD53_CHEK2_ST	Q08050	FOXM1	O96017	CHEK2	S717	R716C	716	Missense	proximal	-1	no	10.780	11.276	EPSD	COSMIC	8.561	Up-regulation
CAMK_RAD53_CHEK2_ST	Q08050	FOXM1	O96017	CHEK2	S717	L722P	722	Missense	distal	5	no	10.780	10.846	EPSD	COSMIC	8.561	Up-regulation
CAMK_RAD53_CHEK2_ST	Q08050	FOXM1	O96017	CHEK2	S717	A714T	714	Missense	distal	-3	no	10.780	7.951	EPSD	COSMIC	8.561	Loss
CAMK_RAD53_CHEK2_ST	Q08050	FOXM1	O96017	CHEK2	T719	G721S	721	Missense	proximal	2	no	10.052	10.117	EPSD	COSMIC	8.561	Up-regulation
CAMK_RAD53_CHEK2_ST	Q08050	FOXM1	O96017	CHEK2	T719	R716C	716	Missense	distal	-3	no	10.052	-0.870	EPSD	COSMIC	8.561	Loss
CAMK_RAD53_CHEK2_ST	Q08050	FOXM1	O96017	CHEK2	T719	L722P	722	Missense	distal	3	no	10.052	10.068	EPSD	COSMIC	8.561	Up-regulation
CAMK_RAD53_CHEK2_ST	Q08050	FOXM1	O96017	CHEK2	T719	L724M	724	Missense	distal	5	no	10.052	10.040	EPSD	COSMIC;CCLE	8.561	Down-regulation
CAMK_RAD53_CHEK2_ST	Q08050	FOXM1	O96017	CHEK2	T719	D725G	725	Missense	distal	6	no	10.052	10.238	EPSD	COSMIC	8.561	Up-regulation
CAMK_RAD53_CHEK2_ST	Q08050	FOXM1	O96017	CHEK2	T719	A714T	714	Missense	distal	-5	no	10.052	10.567	EPSD	COSMIC	8.561	Up-regulation
CAMK_RAD53_CHEK2_ST	P18887	XRCC1	O96017	CHEK2	T42	A35P	35	Missense	distal	-7	no	9.596	10.424	EPSD	COSMIC	8.561	Up-regulation
CAMK_RAD53_CHEK2_ST	P18887	XRCC1	O96017	CHEK2	T42	S44L	44	Missense	proximal	2	no	9.596	9.346	EPSD	COSMIC	8.561	Down-regulation
CAMK_RAD53_CHEK2_ST	P18887	XRCC1	O96017	CHEK2	S151	F149V	149	Missense	proximal	-2	no	13.054	14.152	EPSD	COSMIC	8.561	Up-regulation
CAMK_RAD53_CHEK2_ST	P18887	XRCC1	O96017	CHEK2	T166	Q163R	163	Missense	distal	-3	no	5.935	15.884	EPSD	COSMIC	8.561	Gain
CAMK_RAD53_CHEK2_ST	P18887	XRCC1	O96017	CHEK2	S184	P187L	187	Missense	distal	3	no	9.002	8.987	PhosphoSitePlus;EPSD	COSMIC	8.561	Down-regulation
CAMK_RAD53_CHEK2_ST	P18887	XRCC1	O96017	CHEK2	S184	N183I	183	Missense	proximal	-1	no	9.002	9.006	PhosphoSitePlus;EPSD	COSMIC	8.561	Up-regulation
CAMK_RAD53_CHEK2_ST	P18887	XRCC1	O96017	CHEK2	S184	A182T	182	Missense	proximal	-2	no	9.002	8.857	PhosphoSitePlus;EPSD	COSMIC	8.561	Down-regulation
CAMK_RAD53_CHEK2_ST	P18887	XRCC1	O96017	CHEK2	S184	D179V	179	Missense	distal	-5	no	9.002	9.375	PhosphoSitePlus;EPSD	COSMIC	8.561	Up-regulation
CAMK_RAD53_CHEK2_ST	P18887	XRCC1	O96017	CHEK2	S210	A214V	214	Missense	distal	4	no	8.655	8.988	EPSD;PhosphoSitePlus	COSMIC	8.561	Up-regulation
CAMK_RAD53_CHEK2_ST	P18887	XRCC1	O96017	CHEK2	T215	A214V	214	Missense	proximal	-1	no	10.659	11.136	EPSD	COSMIC	8.561	Up-regulation
CAMK_RAD53_CHEK2_ST	P18887	XRCC1	O96017	CHEK2	S241	R246T	246	Missense	distal	5	no	9.554	9.470	EPSD	COSMIC	8.561	Down-regulation
CAMK_RAD53_CHEK2_ST	P18887	XRCC1	O96017	CHEK2	S266	P270A	270	Missense	distal	4	no	9.337	9.514	EPSD	COSMIC	8.561	Up-regulation
CAMK_RAD53_CHEK2_ST	P18887	XRCC1	O96017	CHEK2	S266	P267L	267	Missense	proximal	1	no	9.337	10.627	EPSD	COSMIC	8.561	Up-regulation
CAMK_RAD53_CHEK2_ST	P18887	XRCC1	O96017	CHEK2	T281	P282Q	282	Missense	proximal	1	no	8.144	10.671	EPSD	COSMIC	8.561	Gain
CAMK_RAD53_CHEK2_ST	P18887	XRCC1	O96017	CHEK2	T358	W353C	353	Missense	distal	-5	no	11.769	12.978	EPSD	COSMIC	8.561	Up-regulation
CAMK_RAD53_CHEK2_ST	P18887	XRCC1	O96017	CHEK2	T358	A365T	365	Missense	distal	7	no	11.769	11.772	EPSD	COSMIC	8.561	Up-regulation
CAMK_RAD53_CHEK2_ST	P18887	XRCC1	O96017	CHEK2	T358	H359R	359	Missense	proximal	1	no	11.769	11.469	EPSD	COSMIC	8.561	Down-regulation
CAMK_RAD53_CHEK2_ST	P18887	XRCC1	O96017	CHEK2	T358	H359Q	359	Missense	proximal	1	no	11.769	15.063	EPSD	COSMIC	8.561	Up-regulation
CAMK_RAD53_CHEK2_ST	P18887	XRCC1	O96017	CHEK2	S447	P454H	454	Missense	distal	7	no	10.033	10.032	EPSD	COSMIC	8.561	Down-regulation
CAMK_RAD53_CHEK2_ST	P18887	XRCC1	O96017	CHEK2	S447	P454F	454	Missense	distal	7	no	10.033	10.064	EPSD	COSMIC	8.561	Up-regulation
CAMK_RAD53_CHEK2_ST	P18887	XRCC1	O96017	CHEK2	S447	P451S	451	Missense	distal	4	no	10.033	9.806	EPSD	COSMIC	8.561	Down-regulation
CAMK_RAD53_CHEK2_ST	P18887	XRCC1	O96017	CHEK2	T453	P454F	454	Missense	proximal	1	no	8.547	11.786	EPSD	COSMIC	8.561	Gain
CAMK_RAD53_CHEK2_ST	P18887	XRCC1	O96017	CHEK2	T453	P451S	451	Missense	proximal	-2	no	8.547	8.784	EPSD	COSMIC	8.561	Gain
CAMK_RAD53_CHEK2_ST	P18887	XRCC1	O96017	CHEK2	S475	G472R	472	Missense	distal	-3	no	2.879	8.785	EPSD	COSMIC	8.561	Gain
CAMK_RAD53_CHEK2_ST	P30304	CDC25A	O96017	CHEK2	S23	P21A	21	Missense	proximal	-2	no	10.492	10.894	EPSD	COSMIC	8.561	Up-regulation
CAMK_RAD53_CHEK2_ST	P30304	CDC25A	O96017	CHEK2	S76	N70H	70	Missense	distal	-6	no	12.430	12.709	EPSD	COSMIC	8.561	Up-regulation
CAMK_RAD53_CHEK2_ST	P30304	CDC25A	O96017	CHEK2	S76	S69G	69	Missense	distal	-7	no	12.430	11.958	EPSD	COSMIC	8.561	Down-regulation
CAMK_RAD53_CHEK2_ST	P30304	CDC25A	O96017	CHEK2	S124	D128G	128	Missense	distal	4	no	12.958	12.699	PhosphoSitePlus;EPSD	COSMIC	8.561	Down-regulation
CAMK_RAD53_CHEK2_ST	P30304	CDC25A	O96017	CHEK2	S126	D128G	128	Missense	proximal	2	no	12.035	12.287	EPSD	COSMIC	8.561	Up-regulation
CAMK_RAD53_CHEK2_ST	P30304	CDC25A	O96017	CHEK2	S178	L184F	184	Missense	distal	6	no	13.985	13.346	EPSD;PhosphoSitePlus	COSMIC	8.561	Down-regulation
CAMK_RAD53_CHEK2_ST	P30304	CDC25A	O96017	CHEK2	S239	C236S	236	Missense	distal	-3	no	4.537	8.601	EPSD	COSMIC	8.561	Gain
CAMK_RAD53_CHEK2_ST	P30304	CDC25A	O96017	CHEK2	S293	S293N	293	Missense	central	0	yes	17.004	0.000	EPSD;PhosphoSitePlus	COSMIC	8.561	Loss
CAMK_RAD53_CHEK2_ST	P30304	CDC25A	O96017	CHEK2	S505	S505R	505	Missense	central	0	yes	10.310	0.000	EPSD	COSMIC	8.561	Loss
CAMK_RAD53_CHEK2_ST	P30304	CDC25A	O96017	CHEK2	S505	K500N	500	Missense	distal	-5	no	10.310	9.826	EPSD	COSMIC	8.561	Down-regulation
CAMK_RAD53_CHEK2_ST	Q9UHR4	BAIAP2L1	O96017	CHEK2	S147	S147G	147	Missense	central	0	yes	12.676	0.000	EPSD	COSMIC	8.561	Loss
CAMK_RAD53_CHEK2_ST	Q9UHR4	BAIAP2L1	O96017	CHEK2	S147	N152H	152	Missense	distal	5	no	12.676	12.762	EPSD	COSMIC	8.561	Up-regulation
CAMK_RAD53_CHEK2_ST	Q9UHR4	BAIAP2L1	O96017	CHEK2	S147	R144K	144	Missense	distal	-3	no	12.676	7.591	EPSD	COSMIC	8.561	Loss
CAMK_RAD53_CHEK2_ST	Q9UHR4	BAIAP2L1	O96017	CHEK2	T252	P249S	249	Missense	distal	-3	no	9.111	7.980	EPSD	COSMIC	8.561	Loss
CAMK_RAD53_CHEK2_ST	Q9UHR4	BAIAP2L1	O96017	CHEK2	T252	T252N	252	Missense	central	0	yes	9.111	0.000	EPSD	COSMIC	8.561	Loss
CAMK_RAD53_CHEK2_ST	Q9UHR4	BAIAP2L1	O96017	CHEK2	T252	V254M	254	Missense	proximal	2	no	9.111	9.028	EPSD	COSMIC	8.561	Down-regulation
CAMK_RAD53_CHEK2_ST	Q9UHR4	BAIAP2L1	O96017	CHEK2	T252	S251C	251	Missense	proximal	-1	no	9.111	9.298	EPSD	COSMIC	8.561	Up-regulation
CAMK_RAD53_CHEK2_ST	Q9UHR4	BAIAP2L1	O96017	CHEK2	T294	A287S	287	Missense	distal	-7	no	15.144	16.209	EPSD	COSMIC	8.561	Up-regulation
CAMK_RAD53_CHEK2_ST	Q9UHR4	BAIAP2L1	O96017	CHEK2	S331	G335E	335	Missense	distal	4	no	16.079	15.701	PhosphoSitePlus	COSMIC	8.561	Down-regulation
CAMK_RAD53_CHEK2_ST	Q9NRM7	LATS2	O96017	CHEK2	T5	A8V	8	Missense	distal	3	no	14.160	14.825	EPSD	COSMIC	8.561	Up-regulation
CAMK_RAD53_CHEK2_ST	Q9NRM7	LATS2	O96017	CHEK2	S172	T165A	165	Missense	distal	-7	no	15.417	15.199	EPSD;PhosphoSitePlus	COSMIC	8.561	Down-regulation
CAMK_RAD53_CHEK2_ST	Q9NRM7	LATS2	O96017	CHEK2	S172	R169Q	169	Missense	distal	-3	no	15.417	5.468	EPSD;PhosphoSitePlus	COSMIC;GDSC	8.561	Loss
CAMK_RAD53_CHEK2_ST	Q9NRM7	LATS2	O96017	CHEK2	S172	D178N	178	Missense	distal	6	no	15.417	15.326	EPSD;PhosphoSitePlus	COSMIC	8.561	Down-regulation
CAMK_RAD53_CHEK2_ST	Q9NRM7	LATS2	O96017	CHEK2	S274	R271H	271	Missense	distal	-3	no	14.952	11.219	EPSD	COSMIC;CCLE	8.561	Down-regulation
CAMK_RAD53_CHEK2_ST	Q9NRM7	LATS2	O96017	CHEK2	S274	S274F	274	Missense	central	0	yes	14.952	0.000	EPSD	COSMIC	8.561	Loss
CAMK_RAD53_CHEK2_ST	Q9NRM7	LATS2	O96017	CHEK2	S288	A287D	287	Missense	proximal	-1	no	8.158	8.777	EPSD	COSMIC	8.561	Gain
CAMK_RAD53_CHEK2_ST	Q9NRM7	LATS2	O96017	CHEK2	S380	S380F	380	Missense	central	0	yes	18.133	0.000	EPSD;PhosphoSitePlus	COSMIC	8.561	Loss
CAMK_RAD53_CHEK2_ST	Q9NRM7	LATS2	O96017	CHEK2	S380	R378W	378	Missense	proximal	-2	no	18.133	16.492	EPSD;PhosphoSitePlus	COSMIC	8.561	Down-regulation
CAMK_RAD53_CHEK2_ST	Q9NRM7	LATS2	O96017	CHEK2	S380	D379G	379	Missense	proximal	-1	no	18.133	17.936	EPSD;PhosphoSitePlus	COSMIC	8.561	Down-regulation
CAMK_RAD53_CHEK2_ST	Q9NRM7	LATS2	O96017	CHEK2	S408	R415W	415	Missense	distal	7	no	17.778	17.831	EPSD;PhosphoSitePlus	COSMIC	8.561	Up-regulation
CAMK_RAD53_CHEK2_ST	Q9NRM7	LATS2	O96017	CHEK2	S408	S408C	408	Missense	central	0	yes	17.778	0.000	EPSD;PhosphoSitePlus	COSMIC	8.561	Loss
CAMK_RAD53_CHEK2_ST	Q9NRM7	LATS2	O96017	CHEK2	S408	P401Q	401	Missense	distal	-7	no	17.778	16.945	EPSD;PhosphoSitePlus	COSMIC	8.561	Down-regulation
CAMK_RAD53_CHEK2_ST	Q9NRM7	LATS2	O96017	CHEK2	S446	V447L	447	Missense	proximal	1	no	8.468	10.067	PhosphoSitePlus;EPSD	COSMIC	8.561	Gain
CAMK_RAD53_CHEK2_ST	Q9NRM7	LATS2	O96017	CHEK2	S528	D532N	532	Missense	distal	4	no	13.147	12.787	EPSD	COSMIC	8.561	Down-regulation
CAMK_RAD53_CHEK2_ST	Q9NRM7	LATS2	O96017	CHEK2	S528	Q530L	530	Missense	proximal	2	no	13.147	13.086	EPSD	COSMIC	8.561	Down-regulation
CAMK_RAD53_CHEK2_ST	Q9NRM7	LATS2	O96017	CHEK2	S528	K527Q	527	Missense	proximal	-1	no	13.147	12.638	EPSD	COSMIC	8.561	Down-regulation
CAMK_RAD53_CHEK2_ST	Q9NRM7	LATS2	O96017	CHEK2	S528	R525H	525	Missense	distal	-3	no	13.147	9.414	EPSD	COSMIC;GDSC;CCLE	8.561	Down-regulation
CAMK_RAD53_CHEK2_ST	Q9NRM7	LATS2	O96017	CHEK2	S528	L533P	533	Missense	distal	5	no	13.147	13.212	EPSD	COSMIC	8.561	Up-regulation
CAMK_RAD53_CHEK2_ST	Q9NRM7	LATS2	O96017	CHEK2	S598	K595R	595	Missense	distal	-3	no	6.910	11.994	EPSD	COSMIC	8.561	Gain
CAMK_RAD53_CHEK2_ST	Q9NRM7	LATS2	O96017	CHEK2	S835	P838S	838	Missense	distal	3	no	14.484	14.300	EPSD	COSMIC	8.561	Down-regulation
CAMK_RAD53_CHEK2_ST	P61289	PSME3	O96017	CHEK2	S17	E20K	20	Missense	distal	3	no	11.102	11.441	EPSD	COSMIC	8.561	Up-regulation
CAMK_RAD53_CHEK2_ST	P61289	PSME3	O96017	CHEK2	S24	E20K	20	Missense	distal	-4	no	8.491	9.628	EPSD	COSMIC	8.561	Gain
CAMK_RAD53_CHEK2_ST	P61289	PSME3	O96017	CHEK2	S24	E27K	27	Missense	distal	3	no	8.491	8.830	EPSD	COSMIC	8.561	Gain
CAMK_RAD53_CHEK2_ST	P61289	PSME3	O96017	CHEK2	T207	R203L	203	Missense	distal	-4	no	12.737	11.375	EPSD	COSMIC	8.561	Down-regulation
CAMK_RAD53_CHEK2_ST	P61289	PSME3	O96017	CHEK2	T207	R203C	203	Missense	distal	-4	no	12.737	11.732	EPSD	COSMIC	8.561	Down-regulation
CAMK_RAD53_CHEK2_ST	Q15717	ELAVL1	O96017	CHEK2	S48	E47Q	47	Missense	proximal	-1	no	8.866	8.387	EPSD	COSMIC	8.561	Loss
CAMK_RAD53_CHEK2_ST	Q15717	ELAVL1	O96017	CHEK2	S88	L86H	86	Missense	proximal	-2	no	14.048	14.256	EPSD;PhosphoSitePlus	COSMIC	8.561	Up-regulation
CAMK_RAD53_CHEK2_ST	Q15717	ELAVL1	O96017	CHEK2	S88	Q87H	87	Missense	proximal	-1	no	14.048	14.282	EPSD;PhosphoSitePlus	COSMIC	8.561	Up-regulation
CAMK_RAD53_CHEK2_ST	Q15717	ELAVL1	O96017	CHEK2	S100	A96V	96	Missense	distal	-4	no	10.228	8.729	EPSD;PhosphoSitePlus	COSMIC	8.561	Down-regulation
CAMK_RAD53_CHEK2_ST	Q15717	ELAVL1	O96017	CHEK2	S100	R97L	97	Missense	distal	-3	no	10.228	2.616	EPSD;PhosphoSitePlus	COSMIC	8.561	Loss
CAMK_RAD53_CHEK2_ST	Q15717	ELAVL1	O96017	CHEK2	S100	E101G	101	Missense	proximal	1	no	10.228	10.875	EPSD;PhosphoSitePlus	COSMIC	8.561	Up-regulation
CAMK_RAD53_CHEK2_ST	P29590	PML	O96017	CHEK2	S117	R115H	115	Missense	proximal	-2	no	16.197	15.851	PhosphoSitePlus	COSMIC	8.561	Down-regulation
CAMK_RAD53_CHEK2_ST	P29590	PML	O96017	CHEK2	S117	R114Q	114	Missense	distal	-3	no	16.197	6.248	PhosphoSitePlus	COSMIC	8.561	Loss
CAMK_RAD53_CHEK2_ST	P29590	PML	O96017	CHEK2	S117	S117L	117	Missense	central	0	yes	16.197	0.000	PhosphoSitePlus	COSMIC	8.561	Loss
CAMK_RAD53_CHEK2_ST	P29590	PML	O96017	CHEK2	S117	E110K	110	Missense	distal	-7	no	16.197	16.395	PhosphoSitePlus	COSMIC	8.561	Up-regulation
CAMK_RAD53_CHEK2_ST	P29590	PML	O96017	CHEK2	T198	T198M	198	Missense	central	0	yes	12.540	0.000	EPSD	COSMIC	8.561	Loss
CAMK_RAD53_CHEK2_ST	P29590	PML	O96017	CHEK2	T198	N193S	193	Missense	distal	-5	no	12.540	13.314	EPSD	COSMIC	8.561	Up-regulation
CAMK_RAD53_CHEK2_ST	P29590	PML	O96017	CHEK2	T391	C389Y	389	Missense	proximal	-2	no	8.629	7.736	EPSD	COSMIC	8.561	Loss
CAMK_RAD53_CHEK2_ST	P29590	PML	O96017	CHEK2	T391	Q392K	392	Missense	proximal	1	no	8.629	5.448	EPSD	COSMIC	8.561	Loss
CAMK_RAD53_CHEK2_ST	P29590	PML	O96017	CHEK2	S480	Q483P	483	Missense	distal	3	no	14.890	15.565	EPSD	COSMIC	8.561	Up-regulation
CAMK_RAD53_CHEK2_ST	P29590	PML	O96017	CHEK2	S480	K487M	487	Missense	distal	7	no	14.890	14.908	EPSD	COSMIC	8.561	Up-regulation
CAMK_RAD53_CHEK2_ST	P29590	PML	O96017	CHEK2	S512	S514P	514	Missense	proximal	2	no	8.833	8.781	EPSD	COSMIC	8.561	Down-regulation
CAMK_RAD53_CHEK2_ST	P29590	PML	O96017	CHEK2	S512	P506L	506	Missense	distal	-6	no	8.833	8.633	EPSD	COSMIC	8.561	Down-regulation
CAMK_RAD53_CHEK2_ST	P29590	PML	O96017	CHEK2	T513	S514P	514	Missense	proximal	1	no	12.490	14.008	EPSD	COSMIC	8.561	Up-regulation
CAMK_RAD53_CHEK2_ST	P29590	PML	O96017	CHEK2	T513	P506L	506	Missense	distal	-7	no	12.490	11.781	EPSD	COSMIC	8.561	Down-regulation
CAMK_RAD53_CHEK2_ST	P29590	PML	O96017	CHEK2	S518	S514P	514	Missense	distal	-4	no	11.658	10.949	EPSD	COSMIC	8.561	Down-regulation
CAMK_RAD53_CHEK2_ST	P29590	PML	O96017	CHEK2	S547	A546V	546	Missense	proximal	-1	no	9.517	9.993	EPSD	COSMIC	8.561	Up-regulation
CAMK_RAD53_CHEK2_ST	P29590	PML	O96017	CHEK2	S547	A552V	552	Missense	distal	5	no	9.517	9.388	EPSD	COSMIC	8.561	Down-regulation
CAMK_RAD53_CHEK2_ST	P29590	PML	O96017	CHEK2	S723	K727N	727	Missense	distal	4	no	8.814	8.944	EPSD	COSMIC	8.561	Up-regulation
CAMK_RAD53_CHEK2_ST	P29590	PML	O96017	CHEK2	S723	G720R	720	Missense	distal	-3	no	8.814	14.720	EPSD	COSMIC	8.561	Up-regulation
CAMK_RAD53_CHEK2_ST	P29590	PML	O96017	CHEK2	S739	E740K	740	Missense	proximal	1	no	8.180	9.521	EPSD	COSMIC	8.561	Gain
CAMK_RAD53_CHEK2_ST	P29590	PML	O96017	CHEK2	S804	S804G	804	Missense	central	0	yes	10.647	0.000	EPSD	COSMIC	8.561	Loss
CAMK_RAD53_CHEK2_ST	P29590	PML	O96017	CHEK2	S828	R825S	825	Missense	distal	-3	no	14.637	7.780	EPSD	COSMIC	8.561	Loss
CAMK_RAD53_CHEK2_ST	P29590	PML	O96017	CHEK2	S828	Q830K	830	Missense	proximal	2	no	14.637	14.786	EPSD	COSMIC	8.561	Up-regulation
CAMK_RAD53_CHEK2_ST	P29590	PML	O96017	CHEK2	S828	Y826H	826	Missense	proximal	-2	no	14.637	15.710	EPSD	COSMIC	8.561	Up-regulation
CAMK_RAD53_CHEK2_ST	P29590	PML	O96017	CHEK2	S828	Y823C	823	Missense	distal	-5	no	14.637	15.157	EPSD	COSMIC	8.561	Up-regulation
CAMK_RAD53_CHEK2_ST	P21127	CDK11B	O96017	CHEK2	S38	D40N	40	Missense	proximal	2	no	9.284	9.459	EPSD	COSMIC	8.561	Up-regulation
CAMK_RAD53_CHEK2_ST	P21127	CDK11B	O96017	CHEK2	S38	S38Y	38	Missense	central	0	yes	9.284	0.000	EPSD	COSMIC	8.561	Loss
CAMK_RAD53_CHEK2_ST	P21127	CDK11B	O96017	CHEK2	S38	S38F	38	Missense	central	0	yes	9.284	0.000	EPSD	COSMIC	8.561	Loss
CAMK_RAD53_CHEK2_ST	P21127	CDK11B	O96017	CHEK2	S47	D40N	40	Missense	distal	-7	no	8.311	8.924	EPSD	COSMIC	8.561	Gain
CAMK_RAD53_CHEK2_ST	P21127	CDK11B	O96017	CHEK2	S283	Q280R	280	Missense	distal	-3	no	0.759	10.709	EPSD	COSMIC	8.561	Gain
CAMK_RAD53_CHEK2_ST	P21127	CDK11B	O96017	CHEK2	S434	R433W	433	Missense	proximal	-1	no	8.912	10.120	EPSD	COSMIC	8.561	Up-regulation
CAMK_RAD53_CHEK2_ST	P21127	CDK11B	O96017	CHEK2	S434	L429M	429	Missense	distal	-5	no	8.912	8.409	EPSD	COSMIC	8.561	Loss
CAMK_RAD53_CHEK2_ST	P21127	CDK11B	O96017	CHEK2	T488	E485K	485	Missense	distal	-3	no	6.570	9.397	EPSD	COSMIC	8.561	Gain
CAMK_RAD53_CHEK2_ST	P21127	CDK11B	O96017	CHEK2	T595	L591Q	591	Missense	distal	-4	no	9.509	10.969	EPSD	COSMIC	8.561	Up-regulation
CAMK_RAD53_CHEK2_ST	P21127	CDK11B	O96017	CHEK2	T595	S589F	589	Missense	distal	-6	no	9.509	8.819	EPSD	COSMIC	8.561	Down-regulation
CAMK_RAD53_CHEK2_ST	P21127	CDK11B	O96017	CHEK2	T595	L601Q	601	Missense	distal	6	no	9.509	9.416	EPSD	COSMIC	8.561	Down-regulation
CAMK_RAD53_CHEK2_ST	P21127	CDK11B	O96017	CHEK2	T595	A593S	593	Missense	proximal	-2	no	9.509	9.344	EPSD	COSMIC	8.561	Down-regulation
CAMK_RAD53_CHEK2_ST	P21127	CDK11B	O96017	CHEK2	T595	T595A	595	Missense	central	0	yes	9.509	0.000	EPSD	COSMIC	8.561	Loss
CAMK_RAD53_CHEK2_ST	P21127	CDK11B	O96017	CHEK2	T595	T595N	595	Missense	central	0	yes	9.509	0.000	EPSD	COSMIC	8.561	Loss
CAMK_RAD53_CHEK2_ST	P21127	CDK11B	O96017	CHEK2	T595	P590S	590	Missense	distal	-5	no	9.509	8.949	EPSD	COSMIC	8.561	Down-regulation
CAMK_RAD53_CHEK2_ST	P21127	CDK11B	O96017	CHEK2	T595	T595I	595	Missense	central	0	yes	9.509	0.000	EPSD	COSMIC	8.561	Loss
CAMK_RAD53_CHEK2_ST	P21127	CDK11B	O96017	CHEK2	T675	A670V	670	Missense	distal	-5	no	10.463	10.388	EPSD	COSMIC	8.561	Down-regulation
CAMK_RAD53_CHEK2_ST	P21127	CDK11B	O96017	CHEK2	T675	T675P	675	Missense	central	0	yes	10.463	0.000	EPSD	COSMIC	8.561	Loss
CAMK_RAD53_CHEK2_ST	P21127	CDK11B	O96017	CHEK2	T675	E678V	678	Missense	distal	3	no	10.463	10.754	EPSD	COSMIC	8.561	Up-regulation
CAMK_RAD53_CHEK2_ST	P21127	CDK11B	O96017	CHEK2	T675	K672N	672	Missense	distal	-3	no	10.463	6.850	EPSD	COSMIC	8.561	Loss
CAMK_RAD53_CHEK2_ST	Q01094	E2F1	O96017	CHEK2	S121	G116V	116	Missense	distal	-5	no	8.292	8.792	EPSD	COSMIC	8.561	Gain
CAMK_RAD53_CHEK2_ST	Q01094	E2F1	O96017	CHEK2	S313	S318F	318	Missense	distal	5	no	10.615	10.227	EPSD	COSMIC	8.561	Down-regulation
CAMK_RAD53_CHEK2_ST	Q01094	E2F1	O96017	CHEK2	S313	P312L	312	Missense	proximal	-1	no	10.615	10.593	EPSD	COSMIC	8.561	Down-regulation
CAMK_RAD53_CHEK2_ST	Q01094	E2F1	O96017	CHEK2	T317	S318F	318	Missense	proximal	1	no	4.388	9.144	EPSD	COSMIC	8.561	Gain
CAMK_RAD53_CHEK2_ST	Q01094	E2F1	O96017	CHEK2	S340	S341F	341	Missense	proximal	1	no	5.310	10.066	EPSD	COSMIC	8.561	Gain
CAMK_RAD53_CHEK2_ST	Q01094	E2F1	O96017	CHEK2	S341	P346S	346	Missense	distal	5	no	8.543	8.675	EPSD	COSMIC;GDSC	8.561	Gain
CAMK_RAD53_CHEK2_ST	Q01094	E2F1	O96017	CHEK2	S341	S336L	336	Missense	distal	-5	no	8.543	8.892	EPSD	COSMIC	8.561	Gain
CAMK_RAD53_CHEK2_ST	Q01094	E2F1	O96017	CHEK2	S341	P335S	335	Missense	distal	-6	no	8.543	8.668	EPSD	COSMIC	8.561	Gain
CAMK_RAD53_CHEK2_ST	Q01094	E2F1	O96017	CHEK2	S352	P346S	346	Missense	distal	-6	no	9.172	9.297	EPSD	COSMIC;GDSC	8.561	Up-regulation
CAMK_RAD53_CHEK2_ST	Q01094	E2F1	O96017	CHEK2	S352	L350V	350	Missense	proximal	-2	no	9.172	9.180	EPSD	COSMIC	8.561	Up-regulation
CAMK_RAD53_CHEK2_ST	Q01094	E2F1	O96017	CHEK2	S364	R366Q	366	Missense	proximal	2	no	16.027	15.823	PhosphoSitePlus	COSMIC	8.561	Down-regulation
CAMK_RAD53_CHEK2_ST	Q01094	E2F1	O96017	CHEK2	S382	S382L	382	Missense	central	0	yes	9.663	0.000	EPSD	COSMIC	8.561	Loss
CAMK_RAD53_CHEK2_ST	P10636	MAPT	O96017	CHEK2	T30	R23K	23	Missense	distal	-7	no	8.933	8.665	EPSD	COSMIC	8.561	Down-regulation
CAMK_RAD53_CHEK2_ST	P10636	MAPT	O96017	CHEK2	T167	P160Q	160	Missense	distal	-7	no	11.981	11.149	EPSD	COSMIC	8.561	Down-regulation
CAMK_RAD53_CHEK2_ST	P10636	MAPT	O96017	CHEK2	T167	A166V	166	Missense	proximal	-1	no	11.981	12.458	EPSD	COSMIC;CCLE	8.561	Up-regulation
CAMK_RAD53_CHEK2_ST	P10636	MAPT	O96017	CHEK2	T167	E165K	165	Missense	proximal	-2	no	11.981	12.380	EPSD	COSMIC	8.561	Up-regulation
CAMK_RAD53_CHEK2_ST	P10636	MAPT	O96017	CHEK2	T167	P160S	160	Missense	distal	-7	no	11.981	12.218	EPSD	COSMIC	8.561	Up-regulation
CAMK_RAD53_CHEK2_ST	P10636	MAPT	O96017	CHEK2	T167	G172V	172	Missense	distal	5	no	11.981	12.012	EPSD	COSMIC	8.561	Up-regulation
CAMK_RAD53_CHEK2_ST	P10636	MAPT	O96017	CHEK2	S171	P175S	175	Missense	distal	4	no	11.678	11.451	EPSD	COSMIC	8.561	Down-regulation
CAMK_RAD53_CHEK2_ST	P10636	MAPT	O96017	CHEK2	S171	A166V	166	Missense	distal	-5	no	11.678	11.603	EPSD	COSMIC;CCLE	8.561	Down-regulation
CAMK_RAD53_CHEK2_ST	P10636	MAPT	O96017	CHEK2	S171	E176G	176	Missense	distal	5	no	11.678	11.625	EPSD	COSMIC	8.561	Down-regulation
CAMK_RAD53_CHEK2_ST	P10636	MAPT	O96017	CHEK2	S171	D177G	177	Missense	distal	6	no	11.678	11.863	EPSD	COSMIC	8.561	Up-regulation
CAMK_RAD53_CHEK2_ST	P10636	MAPT	O96017	CHEK2	S171	E165K	165	Missense	distal	-6	no	11.678	11.780	EPSD	COSMIC	8.561	Up-regulation
CAMK_RAD53_CHEK2_ST	P10636	MAPT	O96017	CHEK2	S171	G172V	172	Missense	proximal	1	no	11.678	12.717	EPSD	COSMIC	8.561	Up-regulation
CAMK_RAD53_CHEK2_ST	P10636	MAPT	O96017	CHEK2	S214	E210Q	210	Missense	distal	-4	no	11.886	13.000	EPSD	COSMIC	8.561	Up-regulation
CAMK_RAD53_CHEK2_ST	P10636	MAPT	O96017	CHEK2	S214	G207E	207	Missense	distal	-7	no	11.886	11.489	EPSD	COSMIC	8.561	Down-regulation
CAMK_RAD53_CHEK2_ST	P10636	MAPT	O96017	CHEK2	S341	A337T	337	Missense	distal	-4	no	14.117	13.337	EPSD	COSMIC	8.561	Down-regulation
CAMK_RAD53_CHEK2_ST	P10636	MAPT	O96017	CHEK2	S341	G343R	343	Missense	proximal	2	no	14.117	14.197	EPSD	COSMIC	8.561	Up-regulation
CAMK_RAD53_CHEK2_ST	P10636	MAPT	O96017	CHEK2	S341	D345G	345	Missense	distal	4	no	14.117	13.858	EPSD	COSMIC	8.561	Down-regulation
CAMK_RAD53_CHEK2_ST	P10636	MAPT	O96017	CHEK2	S341	K347N	347	Missense	distal	6	no	14.117	13.767	EPSD	COSMIC	8.561	Down-regulation
CAMK_RAD53_CHEK2_ST	P10636	MAPT	O96017	CHEK2	T403	L410F	410	Missense	distal	7	no	8.883	8.899	EPSD	COSMIC	8.561	Up-regulation
CAMK_RAD53_CHEK2_ST	P10636	MAPT	O96017	CHEK2	T403	R398C	398	Missense	distal	-5	no	8.883	8.734	EPSD	COSMIC	8.561	Down-regulation
CAMK_RAD53_CHEK2_ST	P10636	MAPT	O96017	CHEK2	T403	S396F	396	Missense	distal	-7	no	8.883	5.488	EPSD	COSMIC	8.561	Loss
CAMK_RAD53_CHEK2_ST	P10636	MAPT	O96017	CHEK2	S411	L410F	410	Missense	proximal	-1	no	9.726	10.328	EPSD	COSMIC	8.561	Up-regulation
CAMK_RAD53_CHEK2_ST	P10636	MAPT	O96017	CHEK2	S411	P412S	412	Missense	proximal	1	no	9.726	8.209	EPSD	COSMIC	8.561	Loss
CAMK_RAD53_CHEK2_ST	P10636	MAPT	O96017	CHEK2	S447	R448Q	448	Missense	proximal	1	no	4.974	8.569	EPSD	COSMIC	8.561	Gain
CAMK_RAD53_CHEK2_ST	P10636	MAPT	O96017	CHEK2	S451	S447P	447	Missense	distal	-4	no	14.339	13.630	EPSD	COSMIC	8.561	Down-regulation
CAMK_RAD53_CHEK2_ST	P10636	MAPT	O96017	CHEK2	S451	R448Q	448	Missense	distal	-3	no	14.339	4.390	EPSD	COSMIC	8.561	Loss
CAMK_RAD53_CHEK2_ST	P10636	MAPT	O96017	CHEK2	T529	R526H	526	Missense	distal	-3	no	13.293	9.560	EPSD	COSMIC	8.561	Down-regulation
CAMK_RAD53_CHEK2_ST	P10636	MAPT	O96017	CHEK2	T529	R528S	528	Missense	proximal	-1	no	13.293	13.601	EPSD	COSMIC	8.561	Up-regulation
CAMK_RAD53_CHEK2_ST	P10636	MAPT	O96017	CHEK2	T529	P530S	530	Missense	proximal	1	no	13.293	11.775	EPSD	COSMIC	8.561	Down-regulation
CAMK_RAD53_CHEK2_ST	P10636	MAPT	O96017	CHEK2	T529	P536H	536	Missense	distal	7	no	13.293	13.292	EPSD	COSMIC	8.561	Down-regulation
CAMK_RAD53_CHEK2_ST	P10636	MAPT	O96017	CHEK2	T529	P535Q	535	Missense	distal	6	no	13.293	13.054	EPSD	COSMIC	8.561	Down-regulation
CAMK_RAD53_CHEK2_ST	P10636	MAPT	O96017	CHEK2	S531	R526H	526	Missense	distal	-5	no	16.601	16.472	EPSD	COSMIC	8.561	Down-regulation
CAMK_RAD53_CHEK2_ST	P10636	MAPT	O96017	CHEK2	S531	R528S	528	Missense	distal	-3	no	16.601	9.744	EPSD	COSMIC	8.561	Down-regulation
CAMK_RAD53_CHEK2_ST	P10636	MAPT	O96017	CHEK2	S531	P530S	530	Missense	proximal	-1	no	16.601	16.781	EPSD	COSMIC	8.561	Up-regulation
CAMK_RAD53_CHEK2_ST	P10636	MAPT	O96017	CHEK2	S531	P536H	536	Missense	distal	5	no	16.601	16.678	EPSD	COSMIC	8.561	Up-regulation
CAMK_RAD53_CHEK2_ST	P10636	MAPT	O96017	CHEK2	S531	P535Q	535	Missense	distal	4	no	16.601	16.484	EPSD	COSMIC	8.561	Down-regulation
CAMK_RAD53_CHEK2_ST	P10636	MAPT	O96017	CHEK2	S554	S555F	555	Missense	proximal	1	no	7.792	12.548	EPSD	COSMIC	8.561	Gain
CAMK_RAD53_CHEK2_ST	P10636	MAPT	O96017	CHEK2	T562	V565M	565	Missense	distal	3	no	14.243	14.032	EPSD	COSMIC	8.561	Down-regulation
CAMK_RAD53_CHEK2_ST	P10636	MAPT	O96017	CHEK2	T562	P566S	566	Missense	distal	4	no	14.243	14.016	EPSD	COSMIC	8.561	Down-regulation
CAMK_RAD53_CHEK2_ST	P10636	MAPT	O96017	CHEK2	T562	R559C	559	Missense	distal	-3	no	14.243	3.321	EPSD	COSMIC	8.561	Loss
CAMK_RAD53_CHEK2_ST	P10636	MAPT	O96017	CHEK2	T562	S555F	555	Missense	distal	-7	no	14.243	10.849	EPSD	COSMIC	8.561	Down-regulation
CAMK_RAD53_CHEK2_ST	P10636	MAPT	O96017	CHEK2	T562	P568S	568	Missense	distal	6	no	14.243	14.165	EPSD	COSMIC	8.561	Down-regulation
CAMK_RAD53_CHEK2_ST	P10636	MAPT	O96017	CHEK2	S579	T580N	580	Missense	proximal	1	no	8.875	6.767	EPSD	COSMIC	8.561	Loss
CAMK_RAD53_CHEK2_ST	P10636	MAPT	O96017	CHEK2	S579	G578S	578	Missense	proximal	-1	no	8.875	8.532	EPSD	COSMIC	8.561	Loss
CAMK_RAD53_CHEK2_ST	P10636	MAPT	O96017	CHEK2	S641	H647Y	647	Missense	distal	6	no	10.002	9.257	EPSD	COSMIC	8.561	Down-regulation
CAMK_RAD53_CHEK2_ST	P10636	MAPT	O96017	CHEK2	S673	V680I	680	Missense	distal	7	no	11.912	11.925	EPSD	COSMIC	8.561	Up-regulation
CAMK_RAD53_CHEK2_ST	P10636	MAPT	O96017	CHEK2	S673	S669L	669	Missense	distal	-4	no	11.912	10.426	EPSD	COSMIC	8.561	Down-regulation
CAMK_RAD53_CHEK2_ST	P10636	MAPT	O96017	CHEK2	S673	R666K	666	Missense	distal	-7	no	11.912	11.644	EPSD	COSMIC	8.561	Down-regulation
CAMK_RAD53_CHEK2_ST	P10636	MAPT	O96017	CHEK2	S673	S673F	673	Missense	central	0	yes	11.912	0.000	EPSD	COSMIC	8.561	Loss
CAMK_RAD53_CHEK2_ST	P10636	MAPT	O96017	CHEK2	S673	K670N	670	Missense	distal	-3	no	11.912	8.300	EPSD	COSMIC	8.561	Loss
CAMK_RAD53_CHEK2_ST	P10636	MAPT	O96017	CHEK2	S673	L674Q	674	Missense	proximal	1	no	11.912	13.149	EPSD	COSMIC	8.561	Up-regulation
CAMK_RAD53_CHEK2_ST	P10636	MAPT	O96017	CHEK2	T694	R696H	696	Missense	proximal	2	no	12.559	12.535	EPSD	COSMIC	8.561	Down-regulation
CAMK_RAD53_CHEK2_ST	P10636	MAPT	O96017	CHEK2	T694	R696C	696	Missense	proximal	2	no	12.559	12.322	EPSD	COSMIC	8.561	Down-regulation
CAMK_RAD53_CHEK2_ST	P10636	MAPT	O96017	CHEK2	T703	R696H	696	Missense	distal	-7	no	8.687	9.052	EPSD	COSMIC	8.561	Up-regulation
CAMK_RAD53_CHEK2_ST	P10636	MAPT	O96017	CHEK2	T703	E708D	708	Missense	distal	5	no	8.687	8.579	EPSD	COSMIC	8.561	Down-regulation
CAMK_RAD53_CHEK2_ST	P10636	MAPT	O96017	CHEK2	T703	G706R	706	Missense	distal	3	no	8.687	7.889	EPSD	COSMIC	8.561	Loss
CAMK_RAD53_CHEK2_ST	P10636	MAPT	O96017	CHEK2	T703	V710M	710	Missense	distal	7	no	8.687	8.692	EPSD	COSMIC	8.561	Up-regulation
CAMK_RAD53_CHEK2_ST	P10636	MAPT	O96017	CHEK2	T703	E708K	708	Missense	distal	5	no	8.687	8.721	EPSD	COSMIC	8.561	Up-regulation
CAMK_RAD53_CHEK2_ST	P10636	MAPT	O96017	CHEK2	T703	R696C	696	Missense	distal	-7	no	8.687	7.869	EPSD	COSMIC	8.561	Loss
CAMK_RAD53_CHEK2_ST	P10636	MAPT	O96017	CHEK2	T703	V710A	710	Missense	distal	7	no	8.687	8.680	EPSD	COSMIC	8.561	Down-regulation
CAMK_RAD53_CHEK2_ST	P10636	MAPT	O96017	CHEK2	T703	T703I	703	Missense	central	0	yes	8.687	0.000	EPSD	COSMIC	8.561	Loss
CAMK_RAD53_CHEK2_ST	P54132	BLM	O96017	CHEK2	T36	F32I	32	Missense	distal	-4	no	8.000	8.948	EPSD	COSMIC	8.561	Gain
CAMK_RAD53_CHEK2_ST	P54132	BLM	O96017	CHEK2	T99	G102D	102	Missense	distal	3	no	10.248	10.571	EPSD	COSMIC	8.561	Up-regulation
CAMK_RAD53_CHEK2_ST	P54132	BLM	O96017	CHEK2	T99	G96V	96	Missense	distal	-3	no	10.248	6.709	EPSD	COSMIC	8.561	Loss
CAMK_RAD53_CHEK2_ST	P54132	BLM	O96017	CHEK2	T99	R101T	101	Missense	proximal	2	no	10.248	10.107	EPSD	COSMIC	8.561	Down-regulation
CAMK_RAD53_CHEK2_ST	P54132	BLM	O96017	CHEK2	T99	S104L	104	Missense	distal	5	no	10.248	10.051	EPSD	COSMIC	8.561	Down-regulation
CAMK_RAD53_CHEK2_ST	P54132	BLM	O96017	CHEK2	T99	N92D	92	Missense	distal	-7	no	10.248	9.635	EPSD	COSMIC;GDSC	8.561	Down-regulation
CAMK_RAD53_CHEK2_ST	P54132	BLM	O96017	CHEK2	S104	G102D	102	Missense	proximal	-2	no	11.214	10.937	EPSD	COSMIC	8.561	Down-regulation
CAMK_RAD53_CHEK2_ST	P54132	BLM	O96017	CHEK2	S104	F111V	111	Missense	distal	7	no	11.214	11.193	EPSD	COSMIC	8.561	Down-regulation
CAMK_RAD53_CHEK2_ST	P54132	BLM	O96017	CHEK2	S104	P109L	109	Missense	distal	5	no	11.214	11.148	EPSD	COSMIC	8.561	Down-regulation
CAMK_RAD53_CHEK2_ST	P54132	BLM	O96017	CHEK2	S104	P109S	109	Missense	distal	5	no	11.214	11.346	EPSD	COSMIC	8.561	Up-regulation
CAMK_RAD53_CHEK2_ST	P54132	BLM	O96017	CHEK2	S104	R101T	101	Missense	distal	-3	no	11.214	2.671	EPSD	COSMIC	8.561	Loss
CAMK_RAD53_CHEK2_ST	P54132	BLM	O96017	CHEK2	S104	D110Y	110	Missense	distal	6	no	11.214	11.033	EPSD	COSMIC	8.561	Down-regulation
CAMK_RAD53_CHEK2_ST	P54132	BLM	O96017	CHEK2	S104	S104L	104	Missense	central	0	yes	11.214	0.000	EPSD	COSMIC	8.561	Loss
CAMK_RAD53_CHEK2_ST	P54132	BLM	O96017	CHEK2	S104	L107S	107	Missense	distal	3	no	11.214	11.045	EPSD	COSMIC	8.561	Down-regulation
CAMK_RAD53_CHEK2_ST	P54132	BLM	O96017	CHEK2	T182	H176D	176	Missense	distal	-6	no	15.547	15.079	PhosphoSitePlus	COSMIC	8.561	Down-regulation
CAMK_RAD53_CHEK2_ST	P54132	BLM	O96017	CHEK2	S269	K271R	271	Missense	proximal	2	no	11.009	11.064	EPSD	COSMIC	8.561	Up-regulation
CAMK_RAD53_CHEK2_ST	P54132	BLM	O96017	CHEK2	S314	S315Y	315	Missense	proximal	1	no	8.881	10.323	EPSD	COSMIC	8.561	Up-regulation
CAMK_RAD53_CHEK2_ST	P54132	BLM	O96017	CHEK2	S314	C318S	318	Missense	distal	4	no	8.881	8.430	EPSD	COSMIC;GDSC;CCLE	8.561	Loss
CAMK_RAD53_CHEK2_ST	P54132	BLM	O96017	CHEK2	S367	H374Y	374	Missense	distal	7	no	11.751	11.781	EPSD	COSMIC	8.561	Up-regulation
CAMK_RAD53_CHEK2_ST	P54132	BLM	O96017	CHEK2	S367	I366T	366	Missense	proximal	-1	no	11.751	11.269	EPSD	COSMIC;GDSC	8.561	Down-regulation
CAMK_RAD53_CHEK2_ST	P54132	BLM	O96017	CHEK2	S367	C361Y	361	Missense	distal	-6	no	11.751	11.453	EPSD	COSMIC;CCLE	8.561	Down-regulation
CAMK_RAD53_CHEK2_ST	P54132	BLM	O96017	CHEK2	S367	A363S	363	Missense	distal	-4	no	11.751	11.911	EPSD	COSMIC	8.561	Up-regulation
CAMK_RAD53_CHEK2_ST	P54132	BLM	O96017	CHEK2	S367	H374D	374	Missense	distal	7	no	11.751	11.773	EPSD	COSMIC	8.561	Up-regulation
CAMK_RAD53_CHEK2_ST	P54132	BLM	O96017	CHEK2	S539	Q533H	533	Missense	distal	-6	no	9.677	9.737	EPSD	COSMIC	8.561	Up-regulation
CAMK_RAD53_CHEK2_ST	P54132	BLM	O96017	CHEK2	S579	S580P	580	Missense	proximal	1	no	8.916	10.433	EPSD	COSMIC	8.561	Up-regulation
CAMK_RAD53_CHEK2_ST	P54132	BLM	O96017	CHEK2	T581	S580P	580	Missense	proximal	-1	no	9.390	9.210	EPSD	COSMIC	8.561	Down-regulation
CAMK_RAD53_CHEK2_ST	P54132	BLM	O96017	CHEK2	S602	D606N	606	Missense	distal	4	no	12.179	11.819	EPSD	COSMIC	8.561	Down-regulation
CAMK_RAD53_CHEK2_ST	P54132	BLM	O96017	CHEK2	S602	R599K	599	Missense	distal	-3	no	12.179	7.094	EPSD	COSMIC	8.561	Loss
CAMK_RAD53_CHEK2_ST	P54132	BLM	O96017	CHEK2	S646	S646G	646	Missense	central	0	yes	13.457	0.000	EPSD	COSMIC	8.561	Loss
CAMK_RAD53_CHEK2_ST	P54132	BLM	O96017	CHEK2	S729	P733S	733	Missense	distal	4	no	9.186	8.959	EPSD	COSMIC	8.561	Down-regulation
CAMK_RAD53_CHEK2_ST	P54132	BLM	O96017	CHEK2	S729	S729F	729	Missense	central	0	yes	9.186	0.000	EPSD	COSMIC	8.561	Loss
CAMK_RAD53_CHEK2_ST	P54132	BLM	O96017	CHEK2	S729	Y736C	736	Missense	distal	7	no	9.186	9.164	EPSD	COSMIC	8.561	Down-regulation
CAMK_RAD53_CHEK2_ST	P54132	BLM	O96017	CHEK2	S1300	S1302F	1302	Missense	proximal	2	no	9.037	8.292	EPSD	COSMIC	8.561	Loss
CAMK_RAD53_CHEK2_ST	P54132	BLM	O96017	CHEK2	S1375	T1371M	1371	Missense	distal	-4	no	8.723	8.020	EPSD	COSMIC	8.561	Loss
CAMK_RAD53_CHEK2_ST	P54132	BLM	O96017	CHEK2	S1375	S1373F	1373	Missense	proximal	-2	no	8.723	7.349	EPSD	COSMIC	8.561	Loss
CAMK_RAD53_CHEK2_ST	P54132	BLM	O96017	CHEK2	S1375	S1368Y	1368	Missense	distal	-7	no	8.723	6.280	EPSD	COSMIC	8.561	Loss
CAMK_RAD53_CHEK2_ST	P54132	BLM	O96017	CHEK2	S1375	S1380R	1380	Missense	distal	5	no	8.723	8.783	EPSD	COSMIC	8.561	Up-regulation
CAMK_RAD53_CHEK2_ST	P54132	BLM	O96017	CHEK2	S1375	A1382T	1382	Missense	distal	7	no	8.723	8.726	EPSD	COSMIC	8.561	Up-regulation
CAMK_RAD53_CHEK2_ST	P54132	BLM	O96017	CHEK2	S1381	S1380R	1380	Missense	proximal	-1	no	9.404	9.096	EPSD	COSMIC	8.561	Down-regulation
CAMK_RAD53_CHEK2_ST	P54132	BLM	O96017	CHEK2	S1381	A1382T	1382	Missense	proximal	1	no	9.404	9.429	EPSD	COSMIC	8.561	Up-regulation
CAMK_RAD53_CHEK2_ST	P54132	BLM	O96017	CHEK2	S1383	S1380R	1380	Missense	distal	-3	no	2.632	9.490	EPSD	COSMIC	8.561	Gain
CAMK_RAD53_CHEK2_ST	P54132	BLM	O96017	CHEK2	S1394	I1398M	1398	Missense	distal	4	no	8.758	8.537	EPSD	COSMIC	8.561	Loss
CAMK_RAD53_CHEK2_ST	P54132	BLM	O96017	CHEK2	S1394	K1395I	1395	Missense	proximal	1	no	8.758	8.518	EPSD	COSMIC	8.561	Loss
CAMK_RAD53_CHEK2_ST	P54132	BLM	O96017	CHEK2	S1394	M1399V	1399	Missense	distal	5	no	8.758	8.816	EPSD	COSMIC	8.561	Up-regulation
CAMK_RAD53_CHEK2_ST	P38398	BRCA1	O96017	CHEK2	S335	C328Y	328	Missense	distal	-7	no	12.925	11.703	EPSD	COSMIC;GDSC;CCLE	8.561	Down-regulation
CAMK_RAD53_CHEK2_ST	P38398	BRCA1	O96017	CHEK2	S335	K338I	338	Missense	distal	3	no	12.925	12.973	EPSD	COSMIC	8.561	Up-regulation
CAMK_RAD53_CHEK2_ST	P38398	BRCA1	O96017	CHEK2	S335	P334S	334	Missense	proximal	-1	no	12.925	13.105	EPSD	COSMIC	8.561	Up-regulation
CAMK_RAD53_CHEK2_ST	P38398	BRCA1	O96017	CHEK2	S335	S335N	335	Missense	central	0	yes	12.925	0.000	EPSD	COSMIC	8.561	Loss
CAMK_RAD53_CHEK2_ST	P38398	BRCA1	O96017	CHEK2	S335	R332Q	332	Missense	distal	-3	no	12.925	2.976	EPSD	COSMIC	8.561	Loss
CAMK_RAD53_CHEK2_ST	P38398	BRCA1	O96017	CHEK2	S335	D330N	330	Missense	distal	-5	no	12.925	12.697	EPSD	COSMIC	8.561	Down-regulation
CAMK_RAD53_CHEK2_ST	P38398	BRCA1	O96017	CHEK2	S335	R332W	332	Missense	distal	-3	no	12.925	-0.303	EPSD	COSMIC	8.561	Loss
CAMK_RAD53_CHEK2_ST	P38398	BRCA1	O96017	CHEK2	S335	R331G	331	Missense	distal	-4	no	12.925	11.970	EPSD	COSMIC	8.561	Down-regulation
CAMK_RAD53_CHEK2_ST	P38398	BRCA1	O96017	CHEK2	S335	S335I	335	Missense	central	0	yes	12.925	0.000	EPSD	COSMIC	8.561	Loss
CAMK_RAD53_CHEK2_ST	P38398	BRCA1	O96017	CHEK2	S335	E337V	337	Missense	proximal	2	no	12.925	12.845	EPSD	COSMIC	8.561	Down-regulation
CAMK_RAD53_CHEK2_ST	P38398	BRCA1	O96017	CHEK2	S449	H448R	448	Missense	proximal	-1	no	10.890	10.635	EPSD	COSMIC	8.561	Down-regulation
CAMK_RAD53_CHEK2_ST	P38398	BRCA1	O96017	CHEK2	S449	K443E	443	Missense	distal	-6	no	10.890	10.787	EPSD	COSMIC	8.561	Down-regulation
CAMK_RAD53_CHEK2_ST	P38398	BRCA1	O96017	CHEK2	S449	N455T	455	Missense	distal	6	no	10.890	11.400	EPSD	COSMIC	8.561	Up-regulation
CAMK_RAD53_CHEK2_ST	P38398	BRCA1	O96017	CHEK2	S449	I456T	456	Missense	distal	7	no	10.890	10.871	EPSD	COSMIC;GDSC;CCLE	8.561	Down-regulation
CAMK_RAD53_CHEK2_ST	P38398	BRCA1	O96017	CHEK2	S451	H448R	448	Missense	distal	-3	no	7.523	11.255	EPSD	COSMIC	8.561	Gain
CAMK_RAD53_CHEK2_ST	P38398	BRCA1	O96017	CHEK2	T509	R506S	506	Missense	distal	-3	no	11.278	4.420	EPSD	COSMIC	8.561	Loss
CAMK_RAD53_CHEK2_ST	P38398	BRCA1	O96017	CHEK2	T509	R504C	504	Missense	distal	-5	no	11.278	11.129	EPSD	COSMIC	8.561	Down-regulation
CAMK_RAD53_CHEK2_ST	P38398	BRCA1	O96017	CHEK2	T509	S510L	510	Missense	proximal	1	no	11.278	14.086	EPSD	COSMIC	8.561	Up-regulation
CAMK_RAD53_CHEK2_ST	P38398	BRCA1	O96017	CHEK2	T509	L512F	512	Missense	distal	3	no	11.278	11.857	EPSD	COSMIC	8.561	Up-regulation
CAMK_RAD53_CHEK2_ST	P38398	BRCA1	O96017	CHEK2	T509	R507K	507	Missense	proximal	-2	no	11.278	11.020	EPSD	COSMIC	8.561	Down-regulation
CAMK_RAD53_CHEK2_ST	P38398	BRCA1	O96017	CHEK2	T509	R507I	507	Missense	proximal	-2	no	11.278	10.746	EPSD	COSMIC	8.561	Down-regulation
CAMK_RAD53_CHEK2_ST	P38398	BRCA1	O96017	CHEK2	S510	R506S	506	Missense	distal	-4	no	12.417	12.541	EPSD	COSMIC	8.561	Up-regulation
CAMK_RAD53_CHEK2_ST	P38398	BRCA1	O96017	CHEK2	S510	R504C	504	Missense	distal	-6	no	12.417	12.167	EPSD	COSMIC	8.561	Down-regulation
CAMK_RAD53_CHEK2_ST	P38398	BRCA1	O96017	CHEK2	S510	S510L	510	Missense	central	0	yes	12.417	0.000	EPSD	COSMIC	8.561	Loss
CAMK_RAD53_CHEK2_ST	P38398	BRCA1	O96017	CHEK2	S510	L512F	512	Missense	proximal	2	no	12.417	11.922	EPSD	COSMIC	8.561	Down-regulation
CAMK_RAD53_CHEK2_ST	P38398	BRCA1	O96017	CHEK2	S510	R507K	507	Missense	distal	-3	no	12.417	7.332	EPSD	COSMIC	8.561	Loss
CAMK_RAD53_CHEK2_ST	P38398	BRCA1	O96017	CHEK2	S510	R507I	507	Missense	distal	-3	no	12.417	2.949	EPSD	COSMIC	8.561	Loss
CAMK_RAD53_CHEK2_ST	P38398	BRCA1	O96017	CHEK2	S615	H619N	619	Missense	distal	4	no	10.681	10.997	EPSD	COSMIC	8.561	Up-regulation
CAMK_RAD53_CHEK2_ST	P38398	BRCA1	O96017	CHEK2	S615	R613K	613	Missense	proximal	-2	no	10.681	10.423	EPSD	COSMIC	8.561	Down-regulation
CAMK_RAD53_CHEK2_ST	P38398	BRCA1	O96017	CHEK2	S615	K608N	608	Missense	distal	-7	no	10.681	9.979	EPSD	COSMIC	8.561	Down-regulation
CAMK_RAD53_CHEK2_ST	P38398	BRCA1	O96017	CHEK2	S615	R610S	610	Missense	distal	-5	no	10.681	10.385	EPSD	COSMIC	8.561	Down-regulation
CAMK_RAD53_CHEK2_ST	P38398	BRCA1	O96017	CHEK2	S615	S616N	616	Missense	proximal	1	no	10.681	10.179	EPSD	COSMIC	8.561	Down-regulation
CAMK_RAD53_CHEK2_ST	P38398	BRCA1	O96017	CHEK2	S616	H619N	619	Missense	distal	3	no	12.246	12.492	EPSD	COSMIC	8.561	Up-regulation
CAMK_RAD53_CHEK2_ST	P38398	BRCA1	O96017	CHEK2	S616	R613K	613	Missense	distal	-3	no	12.246	7.161	EPSD	COSMIC	8.561	Loss
CAMK_RAD53_CHEK2_ST	P38398	BRCA1	O96017	CHEK2	S616	R610S	610	Missense	distal	-6	no	12.246	12.294	EPSD	COSMIC	8.561	Up-regulation
CAMK_RAD53_CHEK2_ST	P38398	BRCA1	O96017	CHEK2	S616	S616N	616	Missense	central	0	yes	12.246	0.000	EPSD	COSMIC	8.561	Loss
CAMK_RAD53_CHEK2_ST	P38398	BRCA1	O96017	CHEK2	T617	H619N	619	Missense	proximal	2	no	9.484	9.351	EPSD	COSMIC	8.561	Down-regulation
CAMK_RAD53_CHEK2_ST	P38398	BRCA1	O96017	CHEK2	T617	R613K	613	Missense	distal	-4	no	9.484	9.604	EPSD	COSMIC	8.561	Up-regulation
CAMK_RAD53_CHEK2_ST	P38398	BRCA1	O96017	CHEK2	T617	R610S	610	Missense	distal	-7	no	9.484	9.887	EPSD	COSMIC	8.561	Up-regulation
CAMK_RAD53_CHEK2_ST	P38398	BRCA1	O96017	CHEK2	T617	S616N	616	Missense	proximal	-1	no	9.484	9.970	EPSD	COSMIC	8.561	Up-regulation
CAMK_RAD53_CHEK2_ST	P38398	BRCA1	O96017	CHEK2	S632	N630H	630	Missense	proximal	-2	no	13.672	13.983	EPSD	COSMIC	8.561	Up-regulation
CAMK_RAD53_CHEK2_ST	P38398	BRCA1	O96017	CHEK2	S632	P633S	633	Missense	proximal	1	no	13.672	12.154	EPSD	COSMIC	8.561	Down-regulation
CAMK_RAD53_CHEK2_ST	P38398	BRCA1	O96017	CHEK2	S632	P634S	634	Missense	proximal	2	no	13.672	13.724	EPSD	COSMIC	8.561	Up-regulation
CAMK_RAD53_CHEK2_ST	P38398	BRCA1	O96017	CHEK2	S632	S628N	628	Missense	distal	-4	no	13.672	12.418	EPSD	COSMIC	8.561	Down-regulation
CAMK_RAD53_CHEK2_ST	P38398	BRCA1	O96017	CHEK2	S632	T637N	637	Missense	distal	5	no	13.672	13.555	EPSD	COSMIC	8.561	Down-regulation
CAMK_RAD53_CHEK2_ST	P38398	BRCA1	O96017	CHEK2	S632	E638D	638	Missense	distal	6	no	13.672	13.547	EPSD	COSMIC	8.561	Down-regulation
CAMK_RAD53_CHEK2_ST	P38398	BRCA1	O96017	CHEK2	S632	C636F	636	Missense	distal	4	no	13.672	14.211	EPSD	COSMIC	8.561	Up-regulation
CAMK_RAD53_CHEK2_ST	P38398	BRCA1	O96017	CHEK2	S632	P634R	634	Missense	proximal	2	no	13.672	13.740	EPSD	COSMIC	8.561	Up-regulation
CAMK_RAD53_CHEK2_ST	P38398	BRCA1	O96017	CHEK2	T637	P634R	634	Missense	distal	-3	no	3.340	9.067	EPSD	COSMIC	8.561	Gain
CAMK_RAD53_CHEK2_ST	P38398	BRCA1	O96017	CHEK2	S694	Q687P	687	Missense	distal	-7	no	14.634	15.467	EPSD	COSMIC;GDSC;CCLE	8.561	Up-regulation
CAMK_RAD53_CHEK2_ST	P38398	BRCA1	O96017	CHEK2	S694	D693N	693	Missense	proximal	-1	no	14.634	14.581	EPSD	COSMIC	8.561	Down-regulation
CAMK_RAD53_CHEK2_ST	P38398	BRCA1	O96017	CHEK2	S694	S694N	694	Missense	central	0	yes	14.634	0.000	EPSD	COSMIC	8.561	Loss
CAMK_RAD53_CHEK2_ST	P38398	BRCA1	O96017	CHEK2	S694	R691I	691	Missense	distal	-3	no	14.634	5.167	EPSD	COSMIC	8.561	Loss
CAMK_RAD53_CHEK2_ST	P38398	BRCA1	O96017	CHEK2	S694	D695N	695	Missense	proximal	1	no	14.634	13.574	EPSD	COSMIC	8.561	Down-regulation
CAMK_RAD53_CHEK2_ST	P38398	BRCA1	O96017	CHEK2	S694	S694F	694	Missense	central	0	yes	14.634	0.000	EPSD	COSMIC	8.561	Loss
CAMK_RAD53_CHEK2_ST	P38398	BRCA1	O96017	CHEK2	S694	S694Y	694	Missense	central	0	yes	14.634	0.000	EPSD	COSMIC	8.561	Loss
CAMK_RAD53_CHEK2_ST	P38398	BRCA1	O96017	CHEK2	T696	D693N	693	Missense	distal	-3	no	10.674	11.216	EPSD	COSMIC	8.561	Up-regulation
CAMK_RAD53_CHEK2_ST	P38398	BRCA1	O96017	CHEK2	T696	S694N	694	Missense	proximal	-2	no	10.674	10.286	EPSD	COSMIC	8.561	Down-regulation
CAMK_RAD53_CHEK2_ST	P38398	BRCA1	O96017	CHEK2	T696	R691I	691	Missense	distal	-5	no	10.674	10.412	EPSD	COSMIC	8.561	Down-regulation
CAMK_RAD53_CHEK2_ST	P38398	BRCA1	O96017	CHEK2	T696	D695N	695	Missense	proximal	-1	no	10.674	10.620	EPSD	COSMIC	8.561	Down-regulation
CAMK_RAD53_CHEK2_ST	P38398	BRCA1	O96017	CHEK2	T696	S694F	694	Missense	proximal	-2	no	10.674	9.299	EPSD	COSMIC	8.561	Down-regulation
CAMK_RAD53_CHEK2_ST	P38398	BRCA1	O96017	CHEK2	T696	S694Y	694	Missense	proximal	-2	no	10.674	9.524	EPSD	COSMIC	8.561	Down-regulation
CAMK_RAD53_CHEK2_ST	P38398	BRCA1	O96017	CHEK2	S803	N810T	810	Missense	distal	7	no	9.025	9.022	EPSD	COSMIC;GDSC;CCLE	8.561	Down-regulation
CAMK_RAD53_CHEK2_ST	P38398	BRCA1	O96017	CHEK2	S803	N810Y	810	Missense	distal	7	no	9.025	9.046	EPSD	COSMIC	8.561	Up-regulation
CAMK_RAD53_CHEK2_ST	P38398	BRCA1	O96017	CHEK2	S803	E809G	809	Missense	distal	6	no	9.025	9.086	EPSD	COSMIC	8.561	Up-regulation
CAMK_RAD53_CHEK2_ST	P38398	BRCA1	O96017	CHEK2	S803	P798S	798	Missense	distal	-5	no	9.025	8.465	EPSD	COSMIC	8.561	Loss
CAMK_RAD53_CHEK2_ST	P38398	BRCA1	O96017	CHEK2	S803	A807T	807	Missense	distal	4	no	9.025	8.885	EPSD	COSMIC	8.561	Down-regulation
CAMK_RAD53_CHEK2_ST	P38398	BRCA1	O96017	CHEK2	S803	T796A	796	Missense	distal	-7	no	9.025	8.808	EPSD	COSMIC	8.561	Down-regulation
CAMK_RAD53_CHEK2_ST	P38398	BRCA1	O96017	CHEK2	S844	E842K	842	Missense	proximal	-2	no	10.747	11.145	EPSD	COSMIC	8.561	Up-regulation
CAMK_RAD53_CHEK2_ST	P38398	BRCA1	O96017	CHEK2	S844	R841W	841	Missense	distal	-3	no	10.747	-2.481	EPSD	COSMIC	8.561	Loss
CAMK_RAD53_CHEK2_ST	P38398	BRCA1	O96017	CHEK2	S844	E849G	849	Missense	distal	5	no	10.747	10.694	EPSD	COSMIC	8.561	Down-regulation
CAMK_RAD53_CHEK2_ST	P38398	BRCA1	O96017	CHEK2	S844	T843A	843	Missense	proximal	-1	no	10.747	10.659	EPSD	COSMIC;GDSC;CCLE	8.561	Down-regulation
CAMK_RAD53_CHEK2_ST	P38398	BRCA1	O96017	CHEK2	S868	P871L	871	Missense	distal	3	no	10.273	10.257	EPSD	COSMIC	8.561	Down-regulation
CAMK_RAD53_CHEK2_ST	P38398	BRCA1	O96017	CHEK2	S868	S868L	868	Missense	central	0	yes	10.273	0.000	EPSD	COSMIC	8.561	Loss
CAMK_RAD53_CHEK2_ST	P38398	BRCA1	O96017	CHEK2	S868	S864L	864	Missense	distal	-4	no	10.273	8.787	EPSD	COSMIC	8.561	Down-regulation
CAMK_RAD53_CHEK2_ST	P38398	BRCA1	O96017	CHEK2	S868	K865N	865	Missense	distal	-3	no	10.273	6.661	EPSD	COSMIC	8.561	Loss
CAMK_RAD53_CHEK2_ST	P38398	BRCA1	O96017	CHEK2	S896	Q895R	895	Missense	proximal	-1	no	8.599	8.578	EPSD	COSMIC	8.561	Down-regulation
CAMK_RAD53_CHEK2_ST	P38398	BRCA1	O96017	CHEK2	S896	G890W	890	Missense	distal	-6	no	8.599	8.097	EPSD	COSMIC	8.561	Loss
CAMK_RAD53_CHEK2_ST	P38398	BRCA1	O96017	CHEK2	S896	G890V	890	Missense	distal	-6	no	8.599	8.437	EPSD	COSMIC;GDSC;CCLE	8.561	Loss
CAMK_RAD53_CHEK2_ST	P38398	BRCA1	O96017	CHEK2	S896	E902Q	902	Missense	distal	6	no	8.599	8.725	EPSD	COSMIC	8.561	Up-regulation
CAMK_RAD53_CHEK2_ST	P38398	BRCA1	O96017	CHEK2	S896	G890R	890	Missense	distal	-6	no	8.599	8.819	EPSD	COSMIC	8.561	Up-regulation
CAMK_RAD53_CHEK2_ST	P38398	BRCA1	O96017	CHEK2	S896	K898E	898	Missense	proximal	2	no	8.599	8.513	EPSD	COSMIC	8.561	Loss
CAMK_RAD53_CHEK2_ST	P38398	BRCA1	O96017	CHEK2	S988	I986M	986	Missense	proximal	-2	no	10.468	10.263	PhosphoSitePlus	COSMIC	8.561	Down-regulation
CAMK_RAD53_CHEK2_ST	P38398	BRCA1	O96017	CHEK2	S1009	E1011K	1011	Missense	proximal	2	no	9.311	9.397	EPSD	COSMIC	8.561	Up-regulation
CAMK_RAD53_CHEK2_ST	P38398	BRCA1	O96017	CHEK2	S1009	M1008I	1008	Missense	proximal	-1	no	9.311	9.759	EPSD	COSMIC;GDSC	8.561	Up-regulation
CAMK_RAD53_CHEK2_ST	P38398	BRCA1	O96017	CHEK2	S1009	M1014I	1014	Missense	distal	5	no	9.311	9.330	EPSD	COSMIC;GDSC;CCLE	8.561	Up-regulation
CAMK_RAD53_CHEK2_ST	P38398	BRCA1	O96017	CHEK2	S1009	M1014K	1014	Missense	distal	5	no	9.311	9.425	EPSD	COSMIC	8.561	Up-regulation
CAMK_RAD53_CHEK2_ST	P38398	BRCA1	O96017	CHEK2	S1009	N1016I	1016	Missense	distal	7	no	9.311	9.326	EPSD	COSMIC	8.561	Up-regulation
CAMK_RAD53_CHEK2_ST	P38398	BRCA1	O96017	CHEK2	S1009	S1009F	1009	Missense	central	0	yes	9.311	0.000	EPSD	COSMIC	8.561	Loss
CAMK_RAD53_CHEK2_ST	P38398	BRCA1	O96017	CHEK2	S1009	E1013D	1013	Missense	distal	4	no	9.311	9.948	EPSD	COSMIC	8.561	Up-regulation
CAMK_RAD53_CHEK2_ST	P38398	BRCA1	O96017	CHEK2	S1164	T1163A	1163	Missense	proximal	-1	no	10.404	10.316	EPSD	COSMIC	8.561	Down-regulation
CAMK_RAD53_CHEK2_ST	P38398	BRCA1	O96017	CHEK2	S1164	E1167K	1167	Missense	distal	3	no	10.404	10.743	EPSD	COSMIC	8.561	Up-regulation
CAMK_RAD53_CHEK2_ST	P38398	BRCA1	O96017	CHEK2	S1178	S1180I	1180	Missense	proximal	2	no	9.007	8.715	EPSD	COSMIC	8.561	Down-regulation
CAMK_RAD53_CHEK2_ST	P38398	BRCA1	O96017	CHEK2	S1178	K1183R	1183	Missense	distal	5	no	9.007	9.163	EPSD	COSMIC	8.561	Up-regulation
CAMK_RAD53_CHEK2_ST	P38398	BRCA1	O96017	CHEK2	S1178	E1185Q	1185	Missense	distal	7	no	9.007	8.994	EPSD	COSMIC	8.561	Down-regulation
CAMK_RAD53_CHEK2_ST	P38398	BRCA1	O96017	CHEK2	S1178	Q1182H	1182	Missense	distal	4	no	9.007	9.170	EPSD	COSMIC	8.561	Up-regulation
CAMK_RAD53_CHEK2_ST	P38398	BRCA1	O96017	CHEK2	S1189	P1190F	1190	Missense	proximal	1	no	6.396	9.635	EPSD	COSMIC	8.561	Gain
CAMK_RAD53_CHEK2_ST	P38398	BRCA1	O96017	CHEK2	S1191	E1185Q	1185	Missense	distal	-6	no	14.099	14.190	EPSD	COSMIC	8.561	Up-regulation
CAMK_RAD53_CHEK2_ST	P38398	BRCA1	O96017	CHEK2	S1191	P1190H	1190	Missense	proximal	-1	no	14.099	14.225	EPSD	COSMIC;GDSC;CCLE	8.561	Up-regulation
CAMK_RAD53_CHEK2_ST	P38398	BRCA1	O96017	CHEK2	S1191	P1190F	1190	Missense	proximal	-1	no	14.099	14.678	EPSD	COSMIC	8.561	Up-regulation
CAMK_RAD53_CHEK2_ST	P38398	BRCA1	O96017	CHEK2	S1191	P1192F	1192	Missense	proximal	1	no	14.099	17.337	EPSD	COSMIC	8.561	Up-regulation
CAMK_RAD53_CHEK2_ST	P38398	BRCA1	O96017	CHEK2	S1191	P1190L	1190	Missense	proximal	-1	no	14.099	14.077	EPSD	COSMIC	8.561	Down-regulation
CAMK_RAD53_CHEK2_ST	P38398	BRCA1	O96017	CHEK2	S1191	P1192S	1192	Missense	proximal	1	no	14.099	12.581	EPSD	COSMIC	8.561	Down-regulation
CAMK_RAD53_CHEK2_ST	P38398	BRCA1	O96017	CHEK2	S1191	P1192L	1192	Missense	proximal	1	no	14.099	15.389	EPSD	COSMIC	8.561	Up-regulation
CAMK_RAD53_CHEK2_ST	P38398	BRCA1	O96017	CHEK2	S1191	R1188K	1188	Missense	distal	-3	no	14.099	9.014	EPSD	COSMIC	8.561	Down-regulation
CAMK_RAD53_CHEK2_ST	P38398	BRCA1	O96017	CHEK2	S1191	H1197Y	1197	Missense	distal	6	no	14.099	13.354	EPSD	COSMIC	8.561	Down-regulation
CAMK_RAD53_CHEK2_ST	P38398	BRCA1	O96017	CHEK2	T1246	Q1240E	1240	Missense	distal	-6	no	11.821	11.729	EPSD	COSMIC	8.561	Down-regulation
CAMK_RAD53_CHEK2_ST	P38398	BRCA1	O96017	CHEK2	T1246	S1245N	1245	Missense	proximal	-1	no	11.821	12.307	EPSD	COSMIC	8.561	Up-regulation
CAMK_RAD53_CHEK2_ST	P38398	BRCA1	O96017	CHEK2	T1246	H1244Y	1244	Missense	proximal	-2	no	11.821	10.748	EPSD	COSMIC	8.561	Down-regulation
CAMK_RAD53_CHEK2_ST	P38398	BRCA1	O96017	CHEK2	T1246	Q1240L	1240	Missense	distal	-6	no	11.821	11.645	EPSD	COSMIC	8.561	Down-regulation
CAMK_RAD53_CHEK2_ST	P38398	BRCA1	O96017	CHEK2	T1246	L1252Q	1252	Missense	distal	6	no	11.821	11.728	EPSD	COSMIC	8.561	Down-regulation
CAMK_RAD53_CHEK2_ST	P38398	BRCA1	O96017	CHEK2	T1246	S1241F	1241	Missense	distal	-5	no	11.821	11.773	EPSD	COSMIC	8.561	Down-regulation
CAMK_RAD53_CHEK2_ST	P38398	BRCA1	O96017	CHEK2	T1246	T1246A	1246	Missense	central	0	yes	11.821	0.000	EPSD	COSMIC	8.561	Loss
CAMK_RAD53_CHEK2_ST	P38398	BRCA1	O96017	CHEK2	T1246	T1249P	1249	Missense	distal	3	no	11.821	11.840	EPSD	COSMIC	8.561	Up-regulation
CAMK_RAD53_CHEK2_ST	P38398	BRCA1	O96017	CHEK2	T1246	S1245Y	1245	Missense	proximal	-1	no	11.821	12.367	EPSD	COSMIC	8.561	Up-regulation
CAMK_RAD53_CHEK2_ST	P38398	BRCA1	O96017	CHEK2	T1246	S1245A	1245	Missense	proximal	-1	no	11.821	11.741	EPSD	COSMIC	8.561	Down-regulation
CAMK_RAD53_CHEK2_ST	P38398	BRCA1	O96017	CHEK2	T1246	S1239T	1239	Missense	distal	-7	no	11.821	10.973	EPSD	COSMIC	8.561	Down-regulation
CAMK_RAD53_CHEK2_ST	P38398	BRCA1	O96017	CHEK2	T1246	S1245F	1245	Missense	proximal	-1	no	11.821	12.220	EPSD	COSMIC	8.561	Up-regulation
CAMK_RAD53_CHEK2_ST	P38398	BRCA1	O96017	CHEK2	S1280	K1278Q	1278	Missense	proximal	-2	no	8.750	8.695	EPSD	COSMIC	8.561	Down-regulation
CAMK_RAD53_CHEK2_ST	P38398	BRCA1	O96017	CHEK2	S1280	S1286T	1286	Missense	distal	6	no	8.750	8.756	EPSD	COSMIC	8.561	Up-regulation
CAMK_RAD53_CHEK2_ST	P38398	BRCA1	O96017	CHEK2	S1280	I1275V	1275	Missense	distal	-5	no	8.750	8.543	EPSD	COSMIC	8.561	Loss
CAMK_RAD53_CHEK2_ST	P38398	BRCA1	O96017	CHEK2	S1280	H1284Y	1284	Missense	distal	4	no	8.750	9.367	EPSD	COSMIC	8.561	Up-regulation
CAMK_RAD53_CHEK2_ST	P38398	BRCA1	O96017	CHEK2	T1312	N1309L	1309	Missense	distal	-3	no	7.627	8.712	EPSD	COSMIC	8.561	Gain
CAMK_RAD53_CHEK2_ST	P38398	BRCA1	O96017	CHEK2	S1328	G1332R	1332	Missense	distal	4	no	10.823	10.179	EPSD	COSMIC	8.561	Down-regulation
CAMK_RAD53_CHEK2_ST	P38398	BRCA1	O96017	CHEK2	S1387	S1387F	1387	Missense	central	0	yes	10.584	0.000	EPSD	COSMIC	8.561	Loss
CAMK_RAD53_CHEK2_ST	P38398	BRCA1	O96017	CHEK2	S1387	G1384W	1384	Missense	distal	-3	no	10.584	3.262	EPSD	COSMIC	8.561	Loss
CAMK_RAD53_CHEK2_ST	P38398	BRCA1	O96017	CHEK2	S1387	T1393N	1393	Missense	distal	6	no	10.584	10.074	EPSD	COSMIC	8.561	Down-regulation
CAMK_RAD53_CHEK2_ST	P38398	BRCA1	O96017	CHEK2	S1387	Q1388E	1388	Missense	proximal	1	no	10.584	6.062	EPSD	COSMIC	8.561	Loss
CAMK_RAD53_CHEK2_ST	P38398	BRCA1	O96017	CHEK2	S1387	Q1388H	1388	Missense	proximal	1	no	10.584	7.290	EPSD	COSMIC	8.561	Loss
CAMK_RAD53_CHEK2_ST	P38398	BRCA1	O96017	CHEK2	S1387	T1394I	1394	Missense	distal	7	no	10.584	10.603	EPSD	COSMIC;CCLE	8.561	Up-regulation
CAMK_RAD53_CHEK2_ST	P38398	BRCA1	O96017	CHEK2	S1387	L1392F	1392	Missense	distal	5	no	10.584	10.393	EPSD	COSMIC	8.561	Down-regulation
CAMK_RAD53_CHEK2_ST	P38398	BRCA1	O96017	CHEK2	S1387	S1387N	1387	Missense	central	0	yes	10.584	0.000	EPSD	COSMIC	8.561	Loss
CAMK_RAD53_CHEK2_ST	P38398	BRCA1	O96017	CHEK2	S1503	P1502L	1502	Missense	proximal	-1	no	9.976	9.954	EPSD	COSMIC	8.561	Down-regulation
CAMK_RAD53_CHEK2_ST	P38398	BRCA1	O96017	CHEK2	S1503	S1499F	1499	Missense	distal	-4	no	9.976	7.094	EPSD	COSMIC	8.561	Loss
CAMK_RAD53_CHEK2_ST	P38398	BRCA1	O96017	CHEK2	S1503	D1506H	1506	Missense	distal	3	no	9.976	9.261	EPSD	COSMIC	8.561	Down-regulation
CAMK_RAD53_CHEK2_ST	P38398	BRCA1	O96017	CHEK2	S1503	S1497P	1497	Missense	distal	-6	no	9.976	9.851	EPSD	COSMIC	8.561	Down-regulation
CAMK_RAD53_CHEK2_ST	P38398	BRCA1	O96017	CHEK2	S1503	W1508C	1508	Missense	distal	5	no	9.976	10.269	EPSD	COSMIC	8.561	Up-regulation
CAMK_RAD53_CHEK2_ST	P38398	BRCA1	O96017	CHEK2	S1503	D1506N	1506	Missense	distal	3	no	9.976	9.507	EPSD	COSMIC	8.561	Down-regulation
CAMK_RAD53_CHEK2_ST	P38398	BRCA1	O96017	CHEK2	S1503	D1505N	1505	Missense	proximal	2	no	9.976	10.151	EPSD	COSMIC;CCLE	8.561	Up-regulation
CAMK_RAD53_CHEK2_ST	P38398	BRCA1	O96017	CHEK2	S1598	P1603T	1603	Missense	distal	5	no	8.549	8.657	EPSD	COSMIC	8.561	Gain
CAMK_RAD53_CHEK2_ST	P38398	BRCA1	O96017	CHEK2	T1658	P1659Q	1659	Missense	proximal	1	no	7.474	10.001	EPSD	COSMIC	8.561	Gain
CAMK_RAD53_CHEK2_ST	P38398	BRCA1	O96017	CHEK2	T1658	P1659L	1659	Missense	proximal	1	no	7.474	8.764	EPSD	COSMIC	8.561	Gain
CAMK_RAD53_CHEK2_ST	P38398	BRCA1	O96017	CHEK2	T1675	A1669S	1669	Missense	distal	-6	no	10.864	11.090	EPSD	COSMIC	8.561	Up-regulation
CAMK_RAD53_CHEK2_ST	P38398	BRCA1	O96017	CHEK2	T1675	L1676F	1676	Missense	proximal	1	no	10.864	12.812	EPSD	COSMIC	8.561	Up-regulation
CAMK_RAD53_CHEK2_ST	P38398	BRCA1	O96017	CHEK2	T1675	T1675A	1675	Missense	central	0	yes	10.864	0.000	EPSD	COSMIC	8.561	Loss
CAMK_RAD53_CHEK2_ST	P38398	BRCA1	O96017	CHEK2	T1675	I1680V	1680	Missense	distal	5	no	10.864	10.903	EPSD	COSMIC	8.561	Up-regulation
CAMK_RAD53_CHEK2_ST	P38398	BRCA1	O96017	CHEK2	T1675	E1682K	1682	Missense	distal	7	no	10.864	10.849	EPSD	COSMIC	8.561	Down-regulation
CAMK_RAD53_CHEK2_ST	P38398	BRCA1	O96017	CHEK2	T1675	I1674F	1674	Missense	proximal	-1	no	10.864	10.773	EPSD	COSMIC	8.561	Down-regulation
CAMK_RAD53_CHEK2_ST	P38398	BRCA1	O96017	CHEK2	T1675	R1670K	1670	Missense	distal	-5	no	10.864	10.278	EPSD	COSMIC	8.561	Down-regulation
CAMK_RAD53_CHEK2_ST	P38398	BRCA1	O96017	CHEK2	T1675	R1670I	1670	Missense	distal	-5	no	10.864	10.602	EPSD	COSMIC	8.561	Down-regulation
CAMK_RAD53_CHEK2_ST	P38398	BRCA1	O96017	CHEK2	T1700	C1697R	1697	Missense	distal	-3	no	2.505	13.427	EPSD	COSMIC	8.561	Gain
CAMK_RAD53_CHEK2_ST	P40337	VHL	O96017	CHEK2	S68	R69C	69	Missense	proximal	1	no	7.351	8.655	EPSD	COSMIC	8.561	Gain
CAMK_RAD53_CHEK2_ST	P40337	VHL	O96017	CHEK2	S72	N78T	78	Missense	distal	6	no	15.594	16.104	EPSD	COSMIC;CCLE	8.561	Up-regulation
CAMK_RAD53_CHEK2_ST	P40337	VHL	O96017	CHEK2	S72	S65T	65	Missense	distal	-7	no	15.594	14.746	EPSD	COSMIC	8.561	Down-regulation
CAMK_RAD53_CHEK2_ST	P40337	VHL	O96017	CHEK2	S72	S68T	68	Missense	distal	-4	no	15.594	14.654	EPSD	COSMIC	8.561	Down-regulation
CAMK_RAD53_CHEK2_ST	P40337	VHL	O96017	CHEK2	S72	F76Y	76	Missense	distal	4	no	15.594	15.492	EPSD	COSMIC	8.561	Down-regulation
CAMK_RAD53_CHEK2_ST	P40337	VHL	O96017	CHEK2	S72	Q73H	73	Missense	proximal	1	no	15.594	12.300	EPSD	COSMIC	8.561	Down-regulation
CAMK_RAD53_CHEK2_ST	P40337	VHL	O96017	CHEK2	S72	P71T	71	Missense	proximal	-1	no	15.594	15.782	EPSD	COSMIC	8.561	Up-regulation
CAMK_RAD53_CHEK2_ST	P40337	VHL	O96017	CHEK2	S72	F76S	76	Missense	distal	4	no	15.594	14.602	EPSD	COSMIC	8.561	Down-regulation
CAMK_RAD53_CHEK2_ST	P40337	VHL	O96017	CHEK2	S72	F76L	76	Missense	distal	4	no	15.594	14.922	EPSD	COSMIC	8.561	Down-regulation
CAMK_RAD53_CHEK2_ST	P40337	VHL	O96017	CHEK2	S72	S65Q	65	Missense	distal	-7	no	15.594	14.525	EPSD	COSMIC	8.561	Down-regulation
CAMK_RAD53_CHEK2_ST	P40337	VHL	O96017	CHEK2	S72	S65A	65	Missense	distal	-7	no	15.594	14.529	EPSD	COSMIC	8.561	Down-regulation
CAMK_RAD53_CHEK2_ST	P40337	VHL	O96017	CHEK2	S72	C77S	77	Missense	distal	5	no	15.594	15.709	EPSD	COSMIC	8.561	Up-regulation
CAMK_RAD53_CHEK2_ST	P40337	VHL	O96017	CHEK2	S72	S72P	72	Missense	central	0	yes	15.594	0.000	EPSD	COSMIC	8.561	Loss
CAMK_RAD53_CHEK2_ST	P40337	VHL	O96017	CHEK2	S72	S68P	68	Missense	distal	-4	no	15.594	14.885	EPSD	COSMIC	8.561	Down-regulation
CAMK_RAD53_CHEK2_ST	P40337	VHL	O96017	CHEK2	S72	Q73K	73	Missense	proximal	1	no	15.594	12.413	EPSD	COSMIC	8.561	Down-regulation
CAMK_RAD53_CHEK2_ST	P40337	VHL	O96017	CHEK2	S72	N67S	67	Missense	distal	-5	no	15.594	16.368	EPSD	COSMIC	8.561	Up-regulation
CAMK_RAD53_CHEK2_ST	P40337	VHL	O96017	CHEK2	S72	I75V	75	Missense	distal	3	no	15.594	15.498	EPSD	COSMIC	8.561	Down-regulation
CAMK_RAD53_CHEK2_ST	P40337	VHL	O96017	CHEK2	S72	N78H	78	Missense	distal	6	no	15.594	16.249	EPSD	COSMIC	8.561	Up-regulation
CAMK_RAD53_CHEK2_ST	P40337	VHL	O96017	CHEK2	S72	S68L	68	Missense	distal	-4	no	15.594	14.108	EPSD	COSMIC	8.561	Down-regulation
CAMK_RAD53_CHEK2_ST	P40337	VHL	O96017	CHEK2	S72	R69C	69	Missense	distal	-3	no	15.594	4.672	EPSD	COSMIC	8.561	Loss
CAMK_RAD53_CHEK2_ST	P40337	VHL	O96017	CHEK2	T100	Y98N	98	Missense	proximal	-2	no	8.443	9.205	EPSD	COSMIC	8.561	Gain
CAMK_RAD53_CHEK2_ST	P40337	VHL	O96017	CHEK2	T100	G93S	93	Missense	distal	-7	no	8.443	8.915	EPSD	COSMIC	8.561	Gain
CAMK_RAD53_CHEK2_ST	P40337	VHL	O96017	CHEK2	T100	Y98S	98	Missense	proximal	-2	no	8.443	9.593	EPSD	COSMIC	8.561	Gain
CAMK_RAD53_CHEK2_ST	P40337	VHL	O96017	CHEK2	T100	Y98C	98	Missense	proximal	-2	no	8.443	9.336	EPSD	COSMIC	8.561	Gain
CAMK_RAD53_CHEK2_ST	P40337	VHL	O96017	CHEK2	T100	L101Q	101	Missense	proximal	1	no	8.443	9.680	EPSD	COSMIC	8.561	Gain
CAMK_RAD53_CHEK2_ST	P40337	VHL	O96017	CHEK2	S111	R107C	107	Missense	distal	-4	no	14.752	13.747	PhosphoSitePlus	COSMIC	8.561	Down-regulation
CAMK_RAD53_CHEK2_ST	P40337	VHL	O96017	CHEK2	S111	G114A	114	Missense	distal	3	no	14.752	14.042	PhosphoSitePlus	COSMIC	8.561	Down-regulation
CAMK_RAD53_CHEK2_ST	P40337	VHL	O96017	CHEK2	S111	H115P	115	Missense	distal	4	no	14.752	14.706	PhosphoSitePlus	COSMIC	8.561	Down-regulation
CAMK_RAD53_CHEK2_ST	P40337	VHL	O96017	CHEK2	S111	G106D	106	Missense	distal	-5	no	14.752	14.880	PhosphoSitePlus	COSMIC	8.561	Up-regulation
CAMK_RAD53_CHEK2_ST	P40337	VHL	O96017	CHEK2	S111	H110Y	110	Missense	proximal	-1	no	14.752	15.352	PhosphoSitePlus	COSMIC	8.561	Up-regulation
CAMK_RAD53_CHEK2_ST	P40337	VHL	O96017	CHEK2	S111	W117R	117	Missense	distal	6	no	14.752	15.629	PhosphoSitePlus	COSMIC	8.561	Up-regulation
CAMK_RAD53_CHEK2_ST	P40337	VHL	O96017	CHEK2	S111	H110Q	110	Missense	proximal	-1	no	14.752	14.518	PhosphoSitePlus	COSMIC	8.561	Down-regulation
CAMK_RAD53_CHEK2_ST	P40337	VHL	O96017	CHEK2	S111	H110N	110	Missense	proximal	-1	no	14.752	15.292	PhosphoSitePlus	COSMIC	8.561	Up-regulation
CAMK_RAD53_CHEK2_ST	P40337	VHL	O96017	CHEK2	S111	G114C	114	Missense	distal	3	no	14.752	14.248	PhosphoSitePlus	COSMIC	8.561	Down-regulation
CAMK_RAD53_CHEK2_ST	P40337	VHL	O96017	CHEK2	S111	G114S	114	Missense	distal	3	no	14.752	14.052	PhosphoSitePlus	COSMIC	8.561	Down-regulation
CAMK_RAD53_CHEK2_ST	P40337	VHL	O96017	CHEK2	S111	Y112D	112	Missense	proximal	1	no	14.752	13.869	PhosphoSitePlus	COSMIC	8.561	Down-regulation
CAMK_RAD53_CHEK2_ST	P40337	VHL	O96017	CHEK2	S111	I109S	109	Missense	proximal	-2	no	14.752	15.015	PhosphoSitePlus	COSMIC	8.561	Up-regulation
CAMK_RAD53_CHEK2_ST	P40337	VHL	O96017	CHEK2	S111	H110R	110	Missense	proximal	-1	no	14.752	14.497	PhosphoSitePlus	COSMIC	8.561	Down-regulation
CAMK_RAD53_CHEK2_ST	P40337	VHL	O96017	CHEK2	S111	L116V	116	Missense	distal	5	no	14.752	14.798	PhosphoSitePlus	COSMIC	8.561	Up-regulation
CAMK_RAD53_CHEK2_ST	P40337	VHL	O96017	CHEK2	S111	G114R	114	Missense	distal	3	no	14.752	13.953	PhosphoSitePlus	COSMIC	8.561	Down-regulation
CAMK_RAD53_CHEK2_ST	P40337	VHL	O96017	CHEK2	S111	G114V	114	Missense	distal	3	no	14.752	14.706	PhosphoSitePlus	COSMIC	8.561	Down-regulation
CAMK_RAD53_CHEK2_ST	P40337	VHL	O96017	CHEK2	S111	T105M	105	Missense	distal	-6	no	14.752	14.547	PhosphoSitePlus	COSMIC	8.561	Down-regulation
CAMK_RAD53_CHEK2_ST	P40337	VHL	O96017	CHEK2	S111	I109F	109	Missense	proximal	-2	no	14.752	13.640	PhosphoSitePlus	COSMIC	8.561	Down-regulation
CAMK_RAD53_CHEK2_ST	P40337	VHL	O96017	CHEK2	S111	G106A	106	Missense	distal	-5	no	14.752	15.327	PhosphoSitePlus	COSMIC	8.561	Up-regulation
CAMK_RAD53_CHEK2_ST	P40337	VHL	O96017	CHEK2	S111	H115L	115	Missense	distal	4	no	14.752	14.799	PhosphoSitePlus	COSMIC	8.561	Up-regulation
CAMK_RAD53_CHEK2_ST	P40337	VHL	O96017	CHEK2	S111	T105K	105	Missense	distal	-6	no	14.752	14.816	PhosphoSitePlus	COSMIC	8.561	Up-regulation
CAMK_RAD53_CHEK2_ST	P40337	VHL	O96017	CHEK2	S111	T105P	105	Missense	distal	-6	no	14.752	14.830	PhosphoSitePlus	COSMIC	8.561	Up-regulation
CAMK_RAD53_CHEK2_ST	P40337	VHL	O96017	CHEK2	S111	G114D	114	Missense	distal	3	no	14.752	15.075	PhosphoSitePlus	COSMIC	8.561	Up-regulation
CAMK_RAD53_CHEK2_ST	P40337	VHL	O96017	CHEK2	S111	L118H	118	Missense	distal	7	no	14.752	14.737	PhosphoSitePlus	COSMIC	8.561	Down-regulation
CAMK_RAD53_CHEK2_ST	P40337	VHL	O96017	CHEK2	S111	W117S	117	Missense	distal	6	no	14.752	15.564	PhosphoSitePlus	COSMIC	8.561	Up-regulation
CAMK_RAD53_CHEK2_ST	P40337	VHL	O96017	CHEK2	S111	G106V	106	Missense	distal	-5	no	14.752	15.253	PhosphoSitePlus	COSMIC	8.561	Up-regulation
CAMK_RAD53_CHEK2_ST	P40337	VHL	O96017	CHEK2	S111	H115D	115	Missense	distal	4	no	14.752	15.427	PhosphoSitePlus	COSMIC	8.561	Up-regulation
CAMK_RAD53_CHEK2_ST	P40337	VHL	O96017	CHEK2	S111	L118R	118	Missense	distal	7	no	14.752	14.731	PhosphoSitePlus	COSMIC	8.561	Down-regulation
CAMK_RAD53_CHEK2_ST	P40337	VHL	O96017	CHEK2	S111	R107G	107	Missense	distal	-4	no	14.752	13.797	PhosphoSitePlus	COSMIC	8.561	Down-regulation
CAMK_RAD53_CHEK2_ST	P40337	VHL	O96017	CHEK2	S111	S111P	111	Missense	central	0	yes	14.752	0.000	PhosphoSitePlus	COSMIC	8.561	Loss
CAMK_RAD53_CHEK2_ST	P40337	VHL	O96017	CHEK2	S168	V165L	165	Missense	distal	-3	no	7.952	9.785	EPSD	COSMIC	8.561	Gain
CAMK_RAD53_CHEK2_ST	P40337	VHL	O96017	CHEK2	S168	L169Q	169	Missense	proximal	1	no	7.952	9.188	EPSD	COSMIC	8.561	Gain
CAMK_RAD53_CHEK2_ST	Q13263	TRIM28	O96017	CHEK2	S41	T34P	34	Missense	distal	-7	no	8.256	8.867	EPSD	COSMIC	8.561	Gain
CAMK_RAD53_CHEK2_ST	Q13263	TRIM28	O96017	CHEK2	S43	A38T	38	Missense	distal	-5	no	9.443	9.958	EPSD	COSMIC	8.561	Up-regulation
CAMK_RAD53_CHEK2_ST	Q13263	TRIM28	O96017	CHEK2	S285	R282H	282	Missense	distal	-3	no	11.409	7.676	EPSD	COSMIC	8.561	Loss
CAMK_RAD53_CHEK2_ST	Q13263	TRIM28	O96017	CHEK2	S285	D286E	286	Missense	proximal	1	no	11.409	10.373	EPSD	COSMIC	8.561	Down-regulation
CAMK_RAD53_CHEK2_ST	Q13263	TRIM28	O96017	CHEK2	S285	K289Q	289	Missense	distal	4	no	11.409	11.060	EPSD	COSMIC	8.561	Down-regulation
CAMK_RAD53_CHEK2_ST	Q13263	TRIM28	O96017	CHEK2	S473	E477D	477	Missense	distal	4	no	14.111	14.747	PhosphoSitePlus	COSMIC	8.561	Up-regulation
CAMK_RAD53_CHEK2_ST	Q13263	TRIM28	O96017	CHEK2	S473	G467D	467	Missense	distal	-6	no	14.111	13.822	PhosphoSitePlus	COSMIC	8.561	Down-regulation
CAMK_RAD53_CHEK2_ST	Q13263	TRIM28	O96017	CHEK2	S473	R472S	472	Missense	proximal	-1	no	14.111	14.419	PhosphoSitePlus	COSMIC	8.561	Up-regulation
CAMK_RAD53_CHEK2_ST	Q13263	TRIM28	O96017	CHEK2	S473	G476C	476	Missense	distal	3	no	14.111	13.607	PhosphoSitePlus	COSMIC	8.561	Down-regulation
CAMK_RAD53_CHEK2_ST	Q13263	TRIM28	O96017	CHEK2	S473	G480V	480	Missense	distal	7	no	14.111	14.118	PhosphoSitePlus	COSMIC	8.561	Up-regulation
CAMK_RAD53_CHEK2_ST	Q13263	TRIM28	O96017	CHEK2	S489	R492L	492	Missense	distal	3	no	8.571	8.839	EPSD	COSMIC	8.561	Up-regulation
CAMK_RAD53_CHEK2_ST	Q13263	TRIM28	O96017	CHEK2	T541	G535V	535	Missense	distal	-6	no	10.217	10.055	EPSD	COSMIC	8.561	Down-regulation
CAMK_RAD53_CHEK2_ST	Q13263	TRIM28	O96017	CHEK2	S594	R591L	591	Missense	distal	-3	no	11.064	3.453	EPSD	COSMIC	8.561	Loss
CAMK_RAD53_CHEK2_ST	Q13263	TRIM28	O96017	CHEK2	S594	P590L	590	Missense	distal	-4	no	11.064	10.287	EPSD	COSMIC	8.561	Down-regulation
CAMK_RAD53_CHEK2_ST	Q13263	TRIM28	O96017	CHEK2	S594	R591C	591	Missense	distal	-3	no	11.064	0.142	EPSD	COSMIC	8.561	Loss
CAMK_RAD53_CHEK2_ST	Q13263	TRIM28	O96017	CHEK2	S598	R591L	591	Missense	distal	-7	no	10.812	10.269	EPSD	COSMIC	8.561	Down-regulation
CAMK_RAD53_CHEK2_ST	Q13263	TRIM28	O96017	CHEK2	S598	R591C	591	Missense	distal	-7	no	10.812	9.994	EPSD	COSMIC	8.561	Down-regulation
CAMK_RAD53_CHEK2_ST	Q13263	TRIM28	O96017	CHEK2	S756	P753H	753	Missense	distal	-3	no	7.124	9.118	EPSD	COSMIC	8.561	Gain
CAMK_RAD53_CHEK2_ST	O15151	MDM4	O96017	CHEK2	T150	S144L	144	Missense	distal	-6	no	17.703	17.378	EPSD	COSMIC	8.561	Down-regulation
CAMK_RAD53_CHEK2_ST	O15151	MDM4	O96017	CHEK2	T150	P156H	156	Missense	distal	6	no	17.703	17.776	EPSD	COSMIC	8.561	Up-regulation
CAMK_RAD53_CHEK2_ST	O15151	MDM4	O96017	CHEK2	T150	I155V	155	Missense	distal	5	no	17.703	17.742	EPSD	COSMIC	8.561	Up-regulation
CAMK_RAD53_CHEK2_ST	O15151	MDM4	O96017	CHEK2	T150	R147K	147	Missense	distal	-3	no	17.703	12.618	EPSD	COSMIC	8.561	Down-regulation
CAMK_RAD53_CHEK2_ST	O15151	MDM4	O96017	CHEK2	T151	S144L	144	Missense	distal	-7	no	8.770	7.824	EPSD	COSMIC	8.561	Loss
CAMK_RAD53_CHEK2_ST	O15151	MDM4	O96017	CHEK2	T151	P156H	156	Missense	distal	5	no	8.770	8.847	EPSD	COSMIC	8.561	Up-regulation
CAMK_RAD53_CHEK2_ST	O15151	MDM4	O96017	CHEK2	T151	I155V	155	Missense	distal	4	no	8.770	8.715	EPSD	COSMIC	8.561	Down-regulation
CAMK_RAD53_CHEK2_ST	O15151	MDM4	O96017	CHEK2	T151	R147K	147	Missense	distal	-4	no	8.770	8.890	EPSD	COSMIC	8.561	Up-regulation
CAMK_RAD53_CHEK2_ST	O15151	MDM4	O96017	CHEK2	S342	L337V	337	Missense	distal	-5	no	10.639	10.117	PhosphoSitePlus;EPSD	COSMIC	8.561	Down-regulation
CAMK_RAD53_CHEK2_ST	O15151	MDM4	O96017	CHEK2	S342	S342F	342	Missense	central	0	yes	10.639	0.000	PhosphoSitePlus;EPSD	COSMIC	8.561	Loss
CAMK_RAD53_CHEK2_ST	O15151	MDM4	O96017	CHEK2	S367	S367L	367	Missense	central	0	yes	16.057	0.000	EPSD;PhosphoSitePlus	COSMIC;GDSC;CCLE	8.561	Loss
CAMK_RAD53_CHEK2_ST	O15151	MDM4	O96017	CHEK2	S367	V370F	370	Missense	distal	3	no	16.057	16.150	EPSD;PhosphoSitePlus	COSMIC	8.561	Up-regulation
CAMK_RAD53_CHEK2_ST	O15151	MDM4	O96017	CHEK2	S367	T365I	365	Missense	proximal	-2	no	16.057	15.775	EPSD;PhosphoSitePlus	COSMIC	8.561	Down-regulation
CAMK_RAD53_CHEK2_ST	O15151	MDM4	O96017	CHEK2	S367	R364G	364	Missense	distal	-3	no	16.057	10.151	EPSD;PhosphoSitePlus	COSMIC	8.561	Down-regulation
CAMK_RAD53_CHEK2_ST	P23560	BDNF	O96017	CHEK2	T62	A60T	60	Missense	proximal	-2	no	8.883	8.738	PhosphoSitePlus	COSMIC	8.561	Down-regulation
CAMK_RAD53_CHEK2_ST	P23560	BDNF	O96017	CHEK2	T62	T57S	57	Missense	distal	-5	no	8.883	8.467	PhosphoSitePlus	COSMIC	8.561	Loss
CAMK_RAD53_CHEK2_ST	P23560	BDNF	O96017	CHEK2	T62	T57I	57	Missense	distal	-5	no	8.883	8.501	PhosphoSitePlus	COSMIC	8.561	Loss
CAMK_RAD53_CHEK2_ST	P30307	CDC25C	O96017	CHEK2	T130	P131L	131	Missense	proximal	1	no	7.453	8.743	EPSD	COSMIC;GDSC;CCLE	8.561	Gain
CAMK_RAD53_CHEK2_ST	P30307	CDC25C	O96017	CHEK2	S216	S216L	216	Missense	central	0	yes	15.096	0.000	PhosphoSitePlus	COSMIC	8.561	Loss
CAMK_RAD53_CHEK2_ST	P30307	CDC25C	O96017	CHEK2	S216	G210R	210	Missense	distal	-6	no	15.096	15.317	PhosphoSitePlus	COSMIC	8.561	Up-regulation
CAMK_RAD53_CHEK2_ST	P30307	CDC25C	O96017	CHEK2	S263	D266H	266	Missense	distal	3	no	11.758	11.043	EPSD	COSMIC	8.561	Down-regulation
CAMK_RAD53_CHEK2_ST	P30307	CDC25C	O96017	CHEK2	S263	L264R	264	Missense	proximal	1	no	11.758	9.400	EPSD	COSMIC	8.561	Down-regulation
CAMK_RAD53_CHEK2_ST	P30307	CDC25C	O96017	CHEK2	S449	R448Q	448	Missense	proximal	-1	no	13.832	13.852	EPSD	COSMIC	8.561	Up-regulation
CAMK_RAD53_CHEK2_ST	P30307	CDC25C	O96017	CHEK2	S449	E443K	443	Missense	distal	-6	no	13.832	13.934	EPSD	COSMIC	8.561	Up-regulation
CAMK_RAD53_CHEK2_ST	P30307	CDC25C	O96017	CHEK2	S451	R448Q	448	Missense	distal	-3	no	9.972	0.023	EPSD	COSMIC	8.561	Loss
CAMK_RAD53_CHEK2_ST	P06400	RB1	O96017	CHEK2	S37	G38F	38	Missense	proximal	1	no	5.106	9.692	EPSD	COSMIC	8.561	Gain
CAMK_RAD53_CHEK2_ST	P06400	RB1	O96017	CHEK2	S260	Q257R	257	Missense	distal	-3	no	3.260	13.209	EPSD	COSMIC	8.561	Gain
CAMK_RAD53_CHEK2_ST	P06400	RB1	O96017	CHEK2	S350	E352K	352	Missense	proximal	2	no	8.629	8.715	EPSD	COSMIC	8.561	Up-regulation
CAMK_RAD53_CHEK2_ST	P06400	RB1	O96017	CHEK2	S360	N361Y	361	Missense	proximal	1	no	6.941	8.884	EPSD	COSMIC	8.561	Gain
CAMK_RAD53_CHEK2_ST	P06400	RB1	O96017	CHEK2	S618	R611S	611	Missense	distal	-7	no	11.075	11.478	EPSD	COSMIC	8.561	Up-regulation
CAMK_RAD53_CHEK2_ST	P06400	RB1	O96017	CHEK2	S618	T620M	620	Missense	proximal	2	no	11.075	10.912	EPSD	COSMIC	8.561	Down-regulation
CAMK_RAD53_CHEK2_ST	P06400	RB1	O96017	CHEK2	S618	S612P	612	Missense	distal	-6	no	11.075	10.950	EPSD	COSMIC	8.561	Down-regulation
CAMK_RAD53_CHEK2_ST	P06400	RB1	O96017	CHEK2	S618	R621C	621	Missense	distal	3	no	11.075	11.369	EPSD	COSMIC	8.561	Up-regulation
CAMK_RAD53_CHEK2_ST	P06400	RB1	O96017	CHEK2	S618	R621S	621	Missense	distal	3	no	11.075	11.173	EPSD	COSMIC;GDSC	8.561	Up-regulation
CAMK_RAD53_CHEK2_ST	P06400	RB1	O96017	CHEK2	S618	T625A	625	Missense	distal	7	no	11.075	11.072	EPSD	COSMIC	8.561	Down-regulation
CAMK_RAD53_CHEK2_ST	P06400	RB1	O96017	CHEK2	S618	R621P	621	Missense	distal	3	no	11.075	11.357	EPSD	COSMIC	8.561	Up-regulation
CAMK_RAD53_CHEK2_ST	P06400	RB1	O96017	CHEK2	T619	T620M	620	Missense	proximal	1	no	10.804	11.421	EPSD	COSMIC	8.561	Up-regulation
CAMK_RAD53_CHEK2_ST	P06400	RB1	O96017	CHEK2	T619	A626G	626	Missense	distal	7	no	10.804	10.805	EPSD	COSMIC	8.561	Up-regulation
CAMK_RAD53_CHEK2_ST	P06400	RB1	O96017	CHEK2	T619	S612P	612	Missense	distal	-7	no	10.804	10.568	EPSD	COSMIC	8.561	Down-regulation
CAMK_RAD53_CHEK2_ST	P06400	RB1	O96017	CHEK2	T619	R621C	621	Missense	proximal	2	no	10.804	10.566	EPSD	COSMIC	8.561	Down-regulation
CAMK_RAD53_CHEK2_ST	P06400	RB1	O96017	CHEK2	T619	R621S	621	Missense	proximal	2	no	10.804	10.788	EPSD	COSMIC;GDSC	8.561	Down-regulation
CAMK_RAD53_CHEK2_ST	P06400	RB1	O96017	CHEK2	T619	T625A	625	Missense	distal	6	no	10.804	10.658	EPSD	COSMIC	8.561	Down-regulation
CAMK_RAD53_CHEK2_ST	P06400	RB1	O96017	CHEK2	T619	R621P	621	Missense	proximal	2	no	10.804	10.736	EPSD	COSMIC	8.561	Down-regulation
CAMK_RAD53_CHEK2_ST	P06400	RB1	O96017	CHEK2	S624	Q631K	631	Missense	distal	7	no	14.601	14.599	EPSD	COSMIC	8.561	Down-regulation
CAMK_RAD53_CHEK2_ST	P06400	RB1	O96017	CHEK2	S624	T620M	620	Missense	distal	-4	no	14.601	13.897	EPSD	COSMIC	8.561	Down-regulation
CAMK_RAD53_CHEK2_ST	P06400	RB1	O96017	CHEK2	S624	A626G	626	Missense	proximal	2	no	14.601	14.586	EPSD	COSMIC	8.561	Down-regulation
CAMK_RAD53_CHEK2_ST	P06400	RB1	O96017	CHEK2	S624	E629K	629	Missense	distal	5	no	14.601	14.634	EPSD	COSMIC	8.561	Up-regulation
CAMK_RAD53_CHEK2_ST	P06400	RB1	O96017	CHEK2	S624	R621C	621	Missense	distal	-3	no	14.601	3.679	EPSD	COSMIC	8.561	Loss
CAMK_RAD53_CHEK2_ST	P06400	RB1	O96017	CHEK2	S624	R621S	621	Missense	distal	-3	no	14.601	7.743	EPSD	COSMIC;GDSC	8.561	Loss
CAMK_RAD53_CHEK2_ST	P06400	RB1	O96017	CHEK2	S624	T625A	625	Missense	proximal	1	no	14.601	14.576	EPSD	COSMIC	8.561	Down-regulation
CAMK_RAD53_CHEK2_ST	P06400	RB1	O96017	CHEK2	S624	R621P	621	Missense	distal	-3	no	14.601	8.874	EPSD	COSMIC	8.561	Down-regulation
CAMK_RAD53_CHEK2_ST	P06400	RB1	O96017	CHEK2	T630	Q631K	631	Missense	proximal	1	no	8.764	5.583	EPSD	COSMIC	8.561	Loss
CAMK_RAD53_CHEK2_ST	P06400	RB1	O96017	CHEK2	T630	S634P	634	Missense	distal	4	no	8.764	8.991	EPSD	COSMIC	8.561	Up-regulation
CAMK_RAD53_CHEK2_ST	P06400	RB1	O96017	CHEK2	T630	A626G	626	Missense	distal	-4	no	8.764	7.845	EPSD	COSMIC	8.561	Loss
CAMK_RAD53_CHEK2_ST	P06400	RB1	O96017	CHEK2	T630	E629K	629	Missense	proximal	-1	no	8.764	8.793	EPSD	COSMIC	8.561	Up-regulation
CAMK_RAD53_CHEK2_ST	P06400	RB1	O96017	CHEK2	T630	T625A	625	Missense	distal	-5	no	8.764	8.249	EPSD	COSMIC	8.561	Loss
CAMK_RAD53_CHEK2_ST	P06400	RB1	O96017	CHEK2	T630	T633A	633	Missense	distal	3	no	8.764	8.589	EPSD	COSMIC	8.561	Down-regulation
CAMK_RAD53_CHEK2_ST	P06400	RB1	O96017	CHEK2	T778	P776R	776	Missense	proximal	-2	no	11.420	11.925	EPSD	COSMIC	8.561	Up-regulation
CAMK_RAD53_CHEK2_ST	P06400	RB1	O96017	CHEK2	T778	H784Y	784	Missense	distal	6	no	11.420	10.675	EPSD	COSMIC	8.561	Down-regulation
CAMK_RAD53_CHEK2_ST	P06400	RB1	O96017	CHEK2	T778	A772S	772	Missense	distal	-6	no	11.420	11.646	EPSD	COSMIC	8.561	Up-regulation
CAMK_RAD53_CHEK2_ST	P06400	RB1	O96017	CHEK2	T778	P777S	777	Missense	proximal	-1	no	11.420	11.600	EPSD	COSMIC	8.561	Up-regulation
CAMK_RAD53_CHEK2_ST	P06400	RB1	O96017	CHEK2	T778	S773F	773	Missense	distal	-5	no	11.420	11.372	EPSD	COSMIC	8.561	Down-regulation
CAMK_RAD53_CHEK2_ST	P06400	RB1	O96017	CHEK2	S780	P776R	776	Missense	distal	-4	no	9.151	9.737	EPSD	COSMIC	8.561	Up-regulation
CAMK_RAD53_CHEK2_ST	P06400	RB1	O96017	CHEK2	S780	H784Y	784	Missense	distal	4	no	9.151	9.768	EPSD	COSMIC	8.561	Up-regulation
CAMK_RAD53_CHEK2_ST	P06400	RB1	O96017	CHEK2	S780	P777S	777	Missense	distal	-3	no	9.151	8.020	EPSD	COSMIC	8.561	Loss
CAMK_RAD53_CHEK2_ST	P06400	RB1	O96017	CHEK2	S780	P786S	786	Missense	distal	6	no	9.151	9.074	EPSD	COSMIC	8.561	Down-regulation
CAMK_RAD53_CHEK2_ST	P06400	RB1	O96017	CHEK2	S780	S773F	773	Missense	distal	-7	no	9.151	5.757	EPSD	COSMIC	8.561	Loss
CAMK_RAD53_CHEK2_ST	P06400	RB1	O96017	CHEK2	T823	G818S	818	Missense	distal	-5	no	9.137	9.810	EPSD	COSMIC	8.561	Up-regulation
CAMK_RAD53_CHEK2_ST	P06400	RB1	O96017	CHEK2	T823	S829L	829	Missense	distal	6	no	9.137	9.068	EPSD	COSMIC	8.561	Down-regulation
CAMK_RAD53_CHEK2_ST	P06400	RB1	O96017	CHEK2	T823	P822S	822	Missense	proximal	-1	no	9.137	9.316	EPSD	COSMIC	8.561	Up-regulation
CAMK_RAD53_CHEK2_ST	P06400	RB1	O96017	CHEK2	T823	G818C	818	Missense	distal	-5	no	9.137	9.957	EPSD	COSMIC	8.561	Up-regulation
CAMK_RAD53_CHEK2_ST	P06400	RB1	O96017	CHEK2	T841	S842F	842	Missense	proximal	1	no	3.901	8.656	EPSD	COSMIC	8.561	Gain
CAMK_RAD53_CHEK2_ST	O60673	REV3L	O96017	CHEK2	S423	R430T	430	Missense	distal	7	no	8.976	8.988	EPSD	COSMIC	8.561	Up-regulation
CAMK_RAD53_CHEK2_ST	O60673	REV3L	O96017	CHEK2	S435	S435G	435	Missense	central	0	yes	12.643	0.000	EPSD	COSMIC	8.561	Loss
CAMK_RAD53_CHEK2_ST	O60673	REV3L	O96017	CHEK2	S435	R430T	430	Missense	distal	-5	no	12.643	12.764	EPSD	COSMIC	8.561	Up-regulation
CAMK_RAD53_CHEK2_ST	O60673	REV3L	O96017	CHEK2	S435	P434S	434	Missense	proximal	-1	no	12.643	12.823	EPSD	COSMIC	8.561	Up-regulation
CAMK_RAD53_CHEK2_ST	O60673	REV3L	O96017	CHEK2	S545	S546F	546	Missense	proximal	1	no	10.208	14.964	EPSD	COSMIC	8.561	Up-regulation
CAMK_RAD53_CHEK2_ST	O60673	REV3L	O96017	CHEK2	S852	E849K	849	Missense	distal	-3	no	5.948	8.775	EPSD	COSMIC	8.561	Gain
CAMK_RAD53_CHEK2_ST	O60673	REV3L	O96017	CHEK2	S1130	P1131L	1131	Missense	proximal	1	no	16.877	18.167	EPSD	COSMIC	8.561	Up-regulation
CAMK_RAD53_CHEK2_ST	O60673	REV3L	O96017	CHEK2	T1224	D1228H	1228	Missense	distal	4	no	16.756	16.081	EPSD	COSMIC	8.561	Down-regulation
CAMK_RAD53_CHEK2_ST	O60673	REV3L	O96017	CHEK2	T1225	D1228H	1228	Missense	distal	3	no	11.775	11.060	EPSD	COSMIC	8.561	Down-regulation
CAMK_RAD53_CHEK2_ST	O60673	REV3L	O96017	CHEK2	S1343	P1339S	1339	Missense	distal	-4	no	8.122	8.831	EPSD	COSMIC	8.561	Gain
CAMK_RAD53_CHEK2_ST	O60673	REV3L	O96017	CHEK2	S1576	N1571S	1571	Missense	distal	-5	no	11.716	12.490	EPSD	COSMIC	8.561	Up-regulation
CAMK_RAD53_CHEK2_ST	O60673	REV3L	O96017	CHEK2	T1578	N1571S	1571	Missense	distal	-7	no	11.860	13.233	EPSD	COSMIC	8.561	Up-regulation
CAMK_RAD53_CHEK2_ST	O60673	REV3L	O96017	CHEK2	T1578	T1585I	1585	Missense	distal	7	no	11.860	11.879	EPSD	COSMIC	8.561	Up-regulation
CAMK_RAD53_CHEK2_ST	O60673	REV3L	O96017	CHEK2	S1757	V1764F	1764	Missense	distal	7	no	14.520	14.541	EPSD	COSMIC	8.561	Up-regulation
CAMK_RAD53_CHEK2_ST	O60673	REV3L	O96017	CHEK2	S1967	G1966R	1966	Missense	proximal	-1	no	11.688	11.037	EPSD	COSMIC	8.561	Down-regulation
CAMK_RAD53_CHEK2_ST	O60673	REV3L	O96017	CHEK2	S1967	G1972D	1972	Missense	distal	5	no	11.688	11.633	EPSD	COSMIC;GDSC;CCLE	8.561	Down-regulation
CAMK_RAD53_CHEK2_ST	O60673	REV3L	O96017	CHEK2	S1967	R1970C	1970	Missense	distal	3	no	11.688	11.982	EPSD	COSMIC	8.561	Up-regulation
CAMK_RAD53_CHEK2_ST	O60673	REV3L	O96017	CHEK2	S2147	S2154I	2154	Missense	distal	7	no	12.232	12.265	EPSD	COSMIC	8.561	Up-regulation
CAMK_RAD53_CHEK2_ST	O60673	REV3L	O96017	CHEK2	T2187	T2187N	2187	Missense	central	0	yes	9.802	0.000	EPSD	COSMIC	8.561	Loss
CAMK_RAD53_CHEK2_ST	O60673	REV3L	O96017	CHEK2	T2187	G2192E	2192	Missense	distal	5	no	9.802	9.855	EPSD	COSMIC	8.561	Up-regulation
CAMK_RAD53_CHEK2_ST	O60673	REV3L	O96017	CHEK2	T2224	E2225K	2225	Missense	proximal	1	no	7.551	8.892	EPSD	COSMIC	8.561	Gain
CAMK_RAD53_CHEK2_ST	O60673	REV3L	O96017	CHEK2	T2363	Q2362P	2362	Missense	proximal	-1	no	10.748	10.856	EPSD	COSMIC	8.561	Up-regulation
CAMK_RAD53_CHEK2_ST	O60673	REV3L	O96017	CHEK2	S2430	C2426R	2426	Missense	distal	-4	no	10.190	11.195	EPSD	COSMIC	8.561	Up-regulation
CAMK_RAD53_CHEK2_ST	O60673	REV3L	O96017	CHEK2	S2884	T2880R	2880	Missense	distal	-4	no	11.433	12.249	EPSD	COSMIC	8.561	Up-regulation
CAMK_CAMK2_CAMK2D_ST	Q08289	CACNB2	Q13557	CAMK2D	S218	R216H	216	Missense	proximal	-2	no	51.476	50.584	EPSD	COSMIC	37.605	Down-regulation
CAMK_CAMK2_CAMK2D_ST	Q08289	CACNB2	Q13557	CAMK2D	S218	S215F	215	Missense	distal	-3	no	51.476	52.663	EPSD	COSMIC	37.605	Up-regulation
CAMK_CAMK2_CAMK2D_ST	Q08289	CACNB2	Q13557	CAMK2D	S218	P220T	220	Missense	proximal	2	no	51.476	50.625	EPSD	COSMIC;GDSC;CCLE	37.605	Down-regulation
CAMK_CAMK2_CAMK2D_ST	Q08289	CACNB2	Q13557	CAMK2D	S218	S214T	214	Missense	distal	-4	no	51.476	53.501	EPSD	COSMIC	37.605	Up-regulation
CAMK_CAMK2_CAMK2D_ST	Q08289	CACNB2	Q13557	CAMK2D	S218	S222L	222	Missense	distal	4	no	51.476	52.517	EPSD	COSMIC	37.605	Up-regulation
CAMK_CAMK2_CAMK2D_ST	Q08289	CACNB2	Q13557	CAMK2D	T219	R216H	216	Missense	distal	-3	no	42.441	5.116	EPSD	COSMIC	37.605	Loss
CAMK_CAMK2_CAMK2D_ST	Q08289	CACNB2	Q13557	CAMK2D	T219	S215F	215	Missense	distal	-4	no	42.441	40.185	EPSD	COSMIC	37.605	Down-regulation
CAMK_CAMK2_CAMK2D_ST	Q08289	CACNB2	Q13557	CAMK2D	T219	P220T	220	Missense	proximal	1	no	42.441	43.672	EPSD	COSMIC;GDSC;CCLE	37.605	Up-regulation
CAMK_CAMK2_CAMK2D_ST	Q08289	CACNB2	Q13557	CAMK2D	T219	S214T	214	Missense	distal	-5	no	42.441	42.932	EPSD	COSMIC	37.605	Up-regulation
CAMK_CAMK2_CAMK2D_ST	Q08289	CACNB2	Q13557	CAMK2D	T219	S222L	222	Missense	distal	3	no	42.441	32.550	EPSD	COSMIC	37.605	Loss
CAMK_CAMK2_CAMK2D_ST	Q08289	CACNB2	Q13557	CAMK2D	S483	S477N	477	Missense	distal	-6	no	34.483	44.136	EPSD	COSMIC	37.605	Gain
CAMK_CAMK2_CAMK2D_ST	Q08289	CACNB2	Q13557	CAMK2D	S514	P509Q	509	Missense	distal	-5	no	56.286	54.499	EPSD	COSMIC	37.605	Down-regulation
CAMK_CAMK2_CAMK2D_ST	Q08289	CACNB2	Q13557	CAMK2D	S514	A508V	508	Missense	distal	-6	no	56.286	50.871	EPSD	COSMIC	37.605	Down-regulation
CAMK_CAMK2_CAMK2D_ST	Q08289	CACNB2	Q13557	CAMK2D	S514	A508D	508	Missense	distal	-6	no	56.286	51.489	EPSD	COSMIC	37.605	Down-regulation
CAMK_CAMK2_CAMK2D_ST	Q08289	CACNB2	Q13557	CAMK2D	S514	A508S	508	Missense	distal	-6	no	56.286	54.998	EPSD	COSMIC	37.605	Down-regulation
CAMK_CAMK2_CAMK2D_ST	Q08289	CACNB2	Q13557	CAMK2D	S514	S507L	507	Missense	distal	-7	no	56.286	59.626	EPSD	COSMIC	37.605	Up-regulation
CAMK_CAMK2_CAMK2D_ST	Q08289	CACNB2	Q13557	CAMK2D	S514	A508T	508	Missense	distal	-6	no	56.286	52.026	EPSD	COSMIC	37.605	Down-regulation
CAMK_CAMK2_CAMK2D_ST	Q08289	CACNB2	Q13557	CAMK2D	S514	Q515H	515	Missense	proximal	1	no	56.286	55.178	EPSD	COSMIC	37.605	Down-regulation
CAMK_CAMK2_CAMK2D_ST	Q08289	CACNB2	Q13557	CAMK2D	S514	I510M	510	Missense	distal	-4	no	56.286	54.532	EPSD	COSMIC	37.605	Down-regulation
CAMK_CAMK2_CAMK2D_ST	Q08289	CACNB2	Q13557	CAMK2D	S514	E517K	517	Missense	distal	3	no	56.286	50.267	EPSD	COSMIC	37.605	Down-regulation
CAMK_CAMK2_CAMK2D_ST	Q08289	CACNB2	Q13557	CAMK2D	S534	S532L	532	Missense	proximal	-2	no	49.774	49.399	EPSD	COSMIC	37.605	Down-regulation
CAMK_CAMK2_CAMK2D_ST	Q08289	CACNB2	Q13557	CAMK2D	S534	H538Q	538	Missense	distal	4	no	49.774	51.959	EPSD	COSMIC	37.605	Up-regulation
CAMK_CAMK2_CAMK2D_ST	Q08289	CACNB2	Q13557	CAMK2D	S534	S533L	533	Missense	proximal	-1	no	49.774	48.341	EPSD	COSMIC	37.605	Down-regulation
CAMK_CAMK2_CAMK2D_ST	Q08289	CACNB2	Q13557	CAMK2D	S534	R531W	531	Missense	distal	-3	no	49.774	8.738	EPSD	COSMIC	37.605	Loss
CAMK_CAMK2_CAMK2D_ST	Q08289	CACNB2	Q13557	CAMK2D	S534	R531Q	531	Missense	distal	-3	no	49.774	38.552	EPSD	COSMIC	37.605	Down-regulation
CAMK_CAMK2_CAMK2D_ST	Q08289	CACNB2	Q13557	CAMK2D	S534	P537Q	537	Missense	distal	3	no	49.774	48.494	EPSD	COSMIC	37.605	Down-regulation
CAMK_CAMK2_CAMK2D_ST	Q08289	CACNB2	Q13557	CAMK2D	S534	A536V	536	Missense	proximal	2	no	49.774	43.899	EPSD	COSMIC	37.605	Down-regulation
CAMK_CAMK2_CAMK2D_ST	Q08289	CACNB2	Q13557	CAMK2D	S534	A536S	536	Missense	proximal	2	no	49.774	48.394	EPSD	COSMIC	37.605	Down-regulation
CAMK_CAMK2_CAMK2D_ST	Q08289	CACNB2	Q13557	CAMK2D	S534	A536D	536	Missense	proximal	2	no	49.774	56.205	EPSD	COSMIC	37.605	Up-regulation
CAMK_CAMK2_CAMK2D_ST	Q08289	CACNB2	Q13557	CAMK2D	S534	S535L	535	Missense	proximal	1	no	49.774	49.680	EPSD	COSMIC	37.605	Down-regulation
CAMK_CAMK2_CAMK2D_ST	Q08289	CACNB2	Q13557	CAMK2D	S534	H530Q	530	Missense	distal	-4	no	49.774	47.711	EPSD	COSMIC	37.605	Down-regulation
CAMK_CAMK2_CAMK2D_ST	Q08289	CACNB2	Q13557	CAMK2D	S534	R531S	531	Missense	distal	-3	no	49.774	33.600	EPSD	COSMIC	37.605	Loss
CAMK_CAMK2_CAMK2D_ST	Q08289	CACNB2	Q13557	CAMK2D	S534	H530Y	530	Missense	distal	-4	no	49.774	51.016	EPSD	COSMIC	37.605	Up-regulation
CAMK_CAMK2_CAMK2D_ST	Q08289	CACNB2	Q13557	CAMK2D	S543	P537Q	537	Missense	distal	-6	no	32.158	38.470	EPSD	COSMIC	37.605	Gain
CAMK_CAMK2_CAMK2D_ST	Q08289	CACNB2	Q13557	CAMK2D	T545	G544R	544	Missense	proximal	-1	no	49.445	51.401	EPSD	COSMIC	37.605	Up-regulation
CAMK_CAMK2_CAMK2D_ST	Q08289	CACNB2	Q13557	CAMK2D	T545	H538Q	538	Missense	distal	-7	no	49.445	51.447	EPSD	COSMIC	37.605	Up-regulation
CAMK_CAMK2_CAMK2D_ST	Q08289	CACNB2	Q13557	CAMK2D	T545	S543I	543	Missense	proximal	-2	no	49.445	49.598	EPSD	COSMIC	37.605	Up-regulation
CAMK_CAMK2_CAMK2D_ST	Q08289	CACNB2	Q13557	CAMK2D	T545	G544V	544	Missense	proximal	-1	no	49.445	50.010	EPSD	COSMIC	37.605	Up-regulation
CAMK_CAMK2_CAMK2D_ST	Q08289	CACNB2	Q13557	CAMK2D	T545	G548S	548	Missense	distal	3	no	49.445	54.312	EPSD	COSMIC	37.605	Up-regulation
CAMK_CAMK2_CAMK2D_ST	Q08289	CACNB2	Q13557	CAMK2D	T545	G544W	544	Missense	proximal	-1	no	49.445	47.336	EPSD	COSMIC	37.605	Down-regulation
CAMK_CAMK2_CAMK2D_ST	Q08289	CACNB2	Q13557	CAMK2D	T545	R547C	547	Missense	proximal	2	no	49.445	46.062	EPSD	COSMIC	37.605	Down-regulation
CAMK_CAMK2_CAMK2D_ST	Q08289	CACNB2	Q13557	CAMK2D	T545	R542H	542	Missense	distal	-3	no	49.445	12.121	EPSD	COSMIC	37.605	Loss
CAMK_CAMK2_CAMK2D_ST	Q08289	CACNB2	Q13557	CAMK2D	T545	G548R	548	Missense	distal	3	no	49.445	52.656	EPSD	COSMIC	37.605	Up-regulation
CAMK_CAMK2_CAMK2D_ST	Q08289	CACNB2	Q13557	CAMK2D	S546	G544R	544	Missense	proximal	-2	no	52.500	53.217	EPSD	COSMIC	37.605	Up-regulation
CAMK_CAMK2_CAMK2D_ST	Q08289	CACNB2	Q13557	CAMK2D	S546	S543I	543	Missense	distal	-3	no	52.500	55.571	EPSD	COSMIC	37.605	Up-regulation
CAMK_CAMK2_CAMK2D_ST	Q08289	CACNB2	Q13557	CAMK2D	S546	G544V	544	Missense	proximal	-2	no	52.500	52.601	EPSD	COSMIC	37.605	Up-regulation
CAMK_CAMK2_CAMK2D_ST	Q08289	CACNB2	Q13557	CAMK2D	S546	G548S	548	Missense	proximal	2	no	52.500	50.420	EPSD	COSMIC	37.605	Down-regulation
CAMK_CAMK2_CAMK2D_ST	Q08289	CACNB2	Q13557	CAMK2D	S546	G544W	544	Missense	proximal	-2	no	52.500	52.031	EPSD	COSMIC	37.605	Down-regulation
CAMK_CAMK2_CAMK2D_ST	Q08289	CACNB2	Q13557	CAMK2D	S546	R547C	547	Missense	proximal	1	no	52.500	41.697	EPSD	COSMIC	37.605	Down-regulation
CAMK_CAMK2_CAMK2D_ST	Q08289	CACNB2	Q13557	CAMK2D	S546	R542H	542	Missense	distal	-4	no	52.500	51.566	EPSD	COSMIC	37.605	Down-regulation
CAMK_CAMK2_CAMK2D_ST	Q08289	CACNB2	Q13557	CAMK2D	S546	G548R	548	Missense	proximal	2	no	52.500	49.614	EPSD	COSMIC	37.605	Down-regulation
CAMK_CAMK2_CAMK2D_ST	Q08289	CACNB2	Q13557	CAMK2D	S550	G544R	544	Missense	distal	-6	no	41.780	43.598	EPSD	COSMIC	37.605	Up-regulation
CAMK_CAMK2_CAMK2D_ST	Q08289	CACNB2	Q13557	CAMK2D	S550	S557F	557	Missense	distal	7	no	41.780	42.430	EPSD	COSMIC	37.605	Up-regulation
CAMK_CAMK2_CAMK2D_ST	Q08289	CACNB2	Q13557	CAMK2D	S550	S543I	543	Missense	distal	-7	no	41.780	44.547	EPSD	COSMIC	37.605	Up-regulation
CAMK_CAMK2_CAMK2D_ST	Q08289	CACNB2	Q13557	CAMK2D	S550	S557L	557	Missense	distal	7	no	41.780	43.665	EPSD	COSMIC	37.605	Up-regulation
CAMK_CAMK2_CAMK2D_ST	Q08289	CACNB2	Q13557	CAMK2D	S550	G544V	544	Missense	distal	-6	no	41.780	36.373	EPSD	COSMIC	37.605	Loss
CAMK_CAMK2_CAMK2D_ST	Q08289	CACNB2	Q13557	CAMK2D	S550	G548S	548	Missense	proximal	-2	no	41.780	41.965	EPSD	COSMIC	37.605	Up-regulation
CAMK_CAMK2_CAMK2D_ST	Q08289	CACNB2	Q13557	CAMK2D	S550	G544W	544	Missense	distal	-6	no	41.780	35.251	EPSD	COSMIC	37.605	Loss
CAMK_CAMK2_CAMK2D_ST	Q08289	CACNB2	Q13557	CAMK2D	S550	R547C	547	Missense	distal	-3	no	41.780	12.278	EPSD	COSMIC	37.605	Loss
CAMK_CAMK2_CAMK2D_ST	Q08289	CACNB2	Q13557	CAMK2D	S550	G548R	548	Missense	proximal	-2	no	41.780	42.497	EPSD	COSMIC	37.605	Up-regulation
CAMK_CAMK2_CAMK2D_ST	Q08289	CACNB2	Q13557	CAMK2D	T554	S557F	557	Missense	distal	3	no	87.151	81.328	EPSD	COSMIC	37.605	Down-regulation
CAMK_CAMK2_CAMK2D_ST	Q08289	CACNB2	Q13557	CAMK2D	T554	S557L	557	Missense	distal	3	no	87.151	77.260	EPSD	COSMIC	37.605	Down-regulation
CAMK_CAMK2_CAMK2D_ST	Q08289	CACNB2	Q13557	CAMK2D	T554	G548S	548	Missense	distal	-6	no	87.151	85.871	EPSD	COSMIC	37.605	Down-regulation
CAMK_CAMK2_CAMK2D_ST	Q08289	CACNB2	Q13557	CAMK2D	T554	R547C	547	Missense	distal	-7	no	87.151	88.870	EPSD	COSMIC	37.605	Up-regulation
CAMK_CAMK2_CAMK2D_ST	Q08289	CACNB2	Q13557	CAMK2D	T554	E558K	558	Missense	distal	4	no	87.151	87.606	EPSD	COSMIC;CCLE	37.605	Up-regulation
CAMK_CAMK2_CAMK2D_ST	Q08289	CACNB2	Q13557	CAMK2D	T554	G548R	548	Missense	distal	-6	no	87.151	88.969	EPSD	COSMIC	37.605	Up-regulation
CAMK_CAMK2_CAMK2D_ST	Q08289	CACNB2	Q13557	CAMK2D	S609	R603H	603	Missense	distal	-6	no	47.359	45.184	EPSD	COSMIC	37.605	Down-regulation
CAMK_CAMK2_CAMK2D_ST	Q08289	CACNB2	Q13557	CAMK2D	S609	R603S	603	Missense	distal	-6	no	47.359	44.261	EPSD	COSMIC	37.605	Down-regulation
CAMK_CAMK2_CAMK2D_ST	Q08289	CACNB2	Q13557	CAMK2D	S609	R603C	603	Missense	distal	-6	no	47.359	44.488	EPSD	COSMIC	37.605	Down-regulation
CAMK_CAMK2_CAMK2D_ST	Q08289	CACNB2	Q13557	CAMK2D	S609	S609F	609	Missense	central	0	yes	47.359	0.000	EPSD	COSMIC	37.605	Loss
CAMK_CAMK2_CAMK2D_ST	Q08289	CACNB2	Q13557	CAMK2D	S609	R610W	610	Missense	proximal	1	no	47.359	41.842	EPSD	COSMIC	37.605	Down-regulation
CAMK_CAMK2_CAMK2D_ST	Q08289	CACNB2	Q13557	CAMK2D	S609	R608H	608	Missense	proximal	-1	no	47.359	42.881	EPSD	COSMIC;CCLE	37.605	Down-regulation
CAMK_CAMK2_CAMK2D_ST	P51787	KCNQ1	Q13557	CAMK2D	S463	G460S	460	Missense	distal	-3	no	16.761	43.545	EPSD	COSMIC	37.605	Gain
CAMK_CAMK2_CAMK2D_ST	P51787	KCNQ1	Q13557	CAMK2D	T470	V474M	474	Missense	distal	4	no	43.465	45.367	EPSD	COSMIC	37.605	Up-regulation
CAMK_CAMK2_CAMK2D_ST	P51787	KCNQ1	Q13557	CAMK2D	T470	E473K	473	Missense	distal	3	no	43.465	37.446	EPSD	COSMIC	37.605	Loss
CAMK_CAMK2_CAMK2D_ST	P51787	KCNQ1	Q13557	CAMK2D	S484	H478Y	478	Missense	distal	-6	no	44.012	39.770	PhosphoSitePlus;EPSD	COSMIC	37.605	Down-regulation
CAMK_CAMK2_CAMK2D_ST	P56524	HDAC4	Q13557	CAMK2D	S210	S210F	210	Missense	central	0	yes	71.895	0.000	PhosphoSitePlus	COSMIC	37.605	Loss
CAMK_CAMK2_CAMK2D_ST	P56524	HDAC4	Q13557	CAMK2D	S210	P216L	216	Missense	distal	6	no	71.895	65.551	PhosphoSitePlus	COSMIC	37.605	Down-regulation
CAMK_CAMK2_CAMK2D_ST	P56524	HDAC4	Q13557	CAMK2D	S210	T206M	206	Missense	distal	-4	no	71.895	68.787	PhosphoSitePlus	COSMIC	37.605	Down-regulation
CAMK_CAMK2_CAMK2D_ST	P56524	HDAC4	Q13557	CAMK2D	S246	F239Y	239	Missense	distal	-7	no	37.379	40.909	EPSD	COSMIC	37.605	Gain
CAMK_CAMK2_CAMK2D_ST	P56524	HDAC4	Q13557	CAMK2D	S246	E247K	247	Missense	proximal	1	no	37.379	37.854	EPSD	COSMIC	37.605	Gain
CAMK_CAMK2_CAMK2D_ST	P56524	HDAC4	Q13557	CAMK2D	S246	P240S	240	Missense	distal	-6	no	37.379	37.731	EPSD	COSMIC	37.605	Gain
CAMK_CAMK2_CAMK2D_ST	P56524	HDAC4	Q13557	CAMK2D	S339	L333P	333	Missense	distal	-6	no	33.046	39.996	EPSD	COSMIC;GDSC;CCLE	37.605	Gain
CAMK_CAMK2_CAMK2D_ST	P56524	HDAC4	Q13557	CAMK2D	T465	Q466E	466	Missense	proximal	1	no	38.887	38.297	EPSD	COSMIC	37.605	Down-regulation
CAMK_CAMK2_CAMK2D_ST	P56524	HDAC4	Q13557	CAMK2D	S584	E587D	587	Missense	distal	3	no	42.806	30.221	EPSD	COSMIC	37.605	Loss
CAMK_CAMK2_CAMK2D_ST	P56524	HDAC4	Q13557	CAMK2D	S584	R581H	581	Missense	distal	-3	no	42.806	5.482	EPSD	COSMIC	37.605	Loss
CAMK_CAMK2_CAMK2D_ST	P56524	HDAC4	Q13557	CAMK2D	S584	S584I	584	Missense	central	0	yes	42.806	0.000	EPSD	COSMIC	37.605	Loss
CAMK_CAMK2_CAMK2D_ST	P56524	HDAC4	Q13557	CAMK2D	S620	G623C	623	Missense	distal	3	no	38.429	44.332	EPSD	COSMIC	37.605	Up-regulation
CAMK_CAMK2_CAMK2D_ST	P56524	HDAC4	Q13557	CAMK2D	S620	A615V	615	Missense	distal	-5	no	38.429	37.597	EPSD	COSMIC	37.605	Loss
CAMK_CAMK2_CAMK2D_ST	P56524	HDAC4	Q13557	CAMK2D	S628	G623C	623	Missense	distal	-5	no	51.960	50.472	EPSD	COSMIC	37.605	Down-regulation
CAMK_CAMK2_CAMK2D_ST	P56524	HDAC4	Q13557	CAMK2D	S628	A635T	635	Missense	distal	7	no	51.960	52.757	EPSD	COSMIC;CCLE	37.605	Up-regulation
CAMK_CAMK2_CAMK2D_ST	P56524	HDAC4	Q13557	CAMK2D	S628	R629Q	629	Missense	proximal	1	no	51.960	46.798	EPSD	COSMIC	37.605	Down-regulation
CAMK_CAMK2_CAMK2D_ST	P56524	HDAC4	Q13557	CAMK2D	S632	A635T	635	Missense	distal	3	no	41.998	28.870	EPSD	COSMIC;CCLE	37.605	Loss
CAMK_CAMK2_CAMK2D_ST	P56524	HDAC4	Q13557	CAMK2D	S632	R629Q	629	Missense	distal	-3	no	41.998	30.775	EPSD	COSMIC	37.605	Loss
CAMK_CAMK2_CAMK2D_ST	P56524	HDAC4	Q13557	CAMK2D	S684	R688H	688	Missense	distal	4	no	51.709	50.136	EPSD	COSMIC;GDSC;CCLE	37.605	Down-regulation
CAMK_CAMK2_CAMK2D_ST	P56524	HDAC4	Q13557	CAMK2D	S684	R688C	688	Missense	distal	4	no	51.709	52.924	EPSD	COSMIC	37.605	Up-regulation
CAMK_CAMK2_CAMK2D_ST	P13688	CEACAM1	Q13557	CAMK2D	T457	G458D	458	Missense	proximal	1	no	49.983	45.058	EPSD;PhosphoSitePlus	COSMIC	37.605	Down-regulation
CAMK_CAMK2_CAMK2D_ST	P13688	CEACAM1	Q13557	CAMK2D	T457	F454L	454	Missense	distal	-3	no	49.983	43.134	EPSD;PhosphoSitePlus	COSMIC	37.605	Down-regulation
CAMK_CAMK2_CAMK2D_ST	P13688	CEACAM1	Q13557	CAMK2D	T457	G455W	455	Missense	proximal	-2	no	49.983	49.514	EPSD;PhosphoSitePlus	COSMIC	37.605	Down-regulation
CAMK_CAMK2_CAMK2D_ST	P13688	CEACAM1	Q13557	CAMK2D	T457	G458S	458	Missense	proximal	1	no	49.983	48.511	EPSD;PhosphoSitePlus	COSMIC;GDSC;CCLE	37.605	Down-regulation
CAMK_CAMK2_CAMK2D_ST	P13688	CEACAM1	Q13557	CAMK2D	T457	R464C	464	Missense	distal	7	no	49.983	51.803	EPSD;PhosphoSitePlus	COSMIC;CCLE	37.605	Up-regulation
CAMK_CAMK2_CAMK2D_ST	P13688	CEACAM1	Q13557	CAMK2D	T457	D462N	462	Missense	distal	5	no	49.983	52.063	EPSD;PhosphoSitePlus	COSMIC	37.605	Up-regulation
CAMK_CAMK2_CAMK2D_ST	P13688	CEACAM1	Q13557	CAMK2D	S494	E490K	490	Missense	distal	-4	no	34.794	38.049	EPSD	COSMIC	37.605	Gain
CAMK_CAMK2_CAMK2D_ST	P13688	CEACAM1	Q13557	CAMK2D	S494	E490V	490	Missense	distal	-4	no	34.794	40.087	EPSD	COSMIC	37.605	Gain
CAMK_CAMK2_CAMK2D_ST	Q8WZ42	TTN	Q13557	CAMK2D	T114	R109G	109	Missense	distal	-5	no	48.847	50.635	EPSD	COSMIC	37.605	Up-regulation
CAMK_CAMK2_CAMK2D_ST	Q8WZ42	TTN	Q13557	CAMK2D	T114	G118E	118	Missense	distal	4	no	48.847	49.113	EPSD	COSMIC	37.605	Up-regulation
CAMK_CAMK2_CAMK2D_ST	Q8WZ42	TTN	Q13557	CAMK2D	T114	Q108E	108	Missense	distal	-6	no	48.847	45.557	EPSD	COSMIC	37.605	Down-regulation
CAMK_CAMK2_CAMK2D_ST	Q8WZ42	TTN	Q13557	CAMK2D	T114	V121L	121	Missense	distal	7	no	48.847	49.486	EPSD	COSMIC	37.605	Up-regulation
CAMK_CAMK2_CAMK2D_ST	Q8WZ42	TTN	Q13557	CAMK2D	T114	Q111H	111	Missense	distal	-3	no	48.847	22.745	EPSD	COSMIC	37.605	Loss
CAMK_CAMK2_CAMK2D_ST	Q8WZ42	TTN	Q13557	CAMK2D	T219	E222K	222	Missense	distal	3	no	47.347	41.327	EPSD	COSMIC	37.605	Down-regulation
CAMK_CAMK2_CAMK2D_ST	Q8WZ42	TTN	Q13557	CAMK2D	T219	K223R	223	Missense	distal	4	no	47.347	46.881	EPSD	COSMIC	37.605	Down-regulation
CAMK_CAMK2_CAMK2D_ST	Q8WZ42	TTN	Q13557	CAMK2D	T219	E226K	226	Missense	distal	7	no	47.347	47.425	EPSD	COSMIC	37.605	Up-regulation
CAMK_CAMK2_CAMK2D_ST	Q8WZ42	TTN	Q13557	CAMK2D	S263	P259S	259	Missense	distal	-4	no	44.737	44.177	EPSD	COSMIC	37.605	Down-regulation
CAMK_CAMK2_CAMK2D_ST	Q8WZ42	TTN	Q13557	CAMK2D	T334	V335M	335	Missense	proximal	1	no	52.348	57.222	EPSD	COSMIC	37.605	Up-regulation
CAMK_CAMK2_CAMK2D_ST	Q8WZ42	TTN	Q13557	CAMK2D	T334	T334A	334	Missense	central	0	yes	52.348	0.000	EPSD	COSMIC	37.605	Loss
CAMK_CAMK2_CAMK2D_ST	Q8WZ42	TTN	Q13557	CAMK2D	T334	M327I	327	Missense	distal	-7	no	52.348	52.702	EPSD	COSMIC	37.605	Up-regulation
CAMK_CAMK2_CAMK2D_ST	Q8WZ42	TTN	Q13557	CAMK2D	T334	G338C	338	Missense	distal	4	no	52.348	53.819	EPSD	COSMIC	37.605	Up-regulation
CAMK_CAMK2_CAMK2D_ST	Q8WZ42	TTN	Q13557	CAMK2D	S353	G349S	349	Missense	distal	-4	no	51.118	51.171	EPSD	COSMIC	37.605	Up-regulation
CAMK_CAMK2_CAMK2D_ST	Q8WZ42	TTN	Q13557	CAMK2D	S353	S354L	354	Missense	proximal	1	no	51.118	51.023	EPSD	COSMIC	37.605	Down-regulation
CAMK_CAMK2_CAMK2D_ST	Q8WZ42	TTN	Q13557	CAMK2D	S353	G349D	349	Missense	distal	-4	no	51.118	49.331	EPSD	COSMIC;GDSC;CCLE	37.605	Down-regulation
CAMK_CAMK2_CAMK2D_ST	Q8WZ42	TTN	Q13557	CAMK2D	S353	R360I	360	Missense	distal	7	no	51.118	52.462	EPSD	COSMIC	37.605	Up-regulation
CAMK_CAMK2_CAMK2D_ST	Q8WZ42	TTN	Q13557	CAMK2D	T363	T366N	366	Missense	distal	3	no	34.930	40.484	EPSD	COSMIC;CCLE	37.605	Gain
CAMK_CAMK2_CAMK2D_ST	Q8WZ42	TTN	Q13557	CAMK2D	T559	E560K	560	Missense	proximal	1	no	46.008	46.482	EPSD	COSMIC	37.605	Up-regulation
CAMK_CAMK2_CAMK2D_ST	Q8WZ42	TTN	Q13557	CAMK2D	T559	E558K	558	Missense	proximal	-1	no	46.008	46.402	EPSD	COSMIC	37.605	Up-regulation
CAMK_CAMK2_CAMK2D_ST	Q8WZ42	TTN	Q13557	CAMK2D	T559	E558D	558	Missense	proximal	-1	no	46.008	43.651	EPSD	COSMIC	37.605	Down-regulation
CAMK_CAMK2_CAMK2D_ST	Q8WZ42	TTN	Q13557	CAMK2D	T559	M566T	566	Missense	distal	7	no	46.008	46.786	EPSD	COSMIC	37.605	Up-regulation
CAMK_CAMK2_CAMK2D_ST	Q8WZ42	TTN	Q13557	CAMK2D	S657	T658R	658	Missense	proximal	1	no	28.991	37.619	EPSD	COSMIC	37.605	Gain
CAMK_CAMK2_CAMK2D_ST	Q8WZ42	TTN	Q13557	CAMK2D	S813	P814H	814	Missense	proximal	1	no	35.082	38.672	EPSD	COSMIC	37.605	Gain
CAMK_CAMK2_CAMK2D_ST	Q8WZ42	TTN	Q13557	CAMK2D	S837	A838T	838	Missense	proximal	1	no	48.246	50.201	EPSD	COSMIC	37.605	Up-regulation
CAMK_CAMK2_CAMK2D_ST	Q8WZ42	TTN	Q13557	CAMK2D	S837	G836D	836	Missense	proximal	-1	no	48.246	46.035	EPSD	COSMIC	37.605	Down-regulation
CAMK_CAMK2_CAMK2D_ST	Q8WZ42	TTN	Q13557	CAMK2D	S837	A838V	838	Missense	proximal	1	no	48.246	54.678	EPSD	COSMIC	37.605	Up-regulation
CAMK_CAMK2_CAMK2D_ST	Q8WZ42	TTN	Q13557	CAMK2D	S905	V902I	902	Missense	distal	-3	no	40.093	39.374	EPSD	COSMIC	37.605	Down-regulation
CAMK_CAMK2_CAMK2D_ST	Q8WZ42	TTN	Q13557	CAMK2D	S905	V902A	902	Missense	distal	-3	no	40.093	26.521	EPSD	COSMIC	37.605	Loss
CAMK_CAMK2_CAMK2D_ST	Q8WZ42	TTN	Q13557	CAMK2D	S905	E901K	901	Missense	distal	-4	no	40.093	43.348	EPSD	COSMIC	37.605	Up-regulation
CAMK_CAMK2_CAMK2D_ST	Q8WZ42	TTN	Q13557	CAMK2D	S905	V904M	904	Missense	proximal	-1	no	40.093	37.927	EPSD	COSMIC	37.605	Down-regulation
CAMK_CAMK2_CAMK2D_ST	Q8WZ42	TTN	Q13557	CAMK2D	T1067	T1070I	1070	Missense	distal	3	no	41.928	39.055	EPSD	COSMIC	37.605	Down-regulation
CAMK_CAMK2_CAMK2D_ST	Q8WZ42	TTN	Q13557	CAMK2D	T1067	D1066N	1066	Missense	proximal	-1	no	41.928	43.914	EPSD	COSMIC	37.605	Up-regulation
CAMK_CAMK2_CAMK2D_ST	Q8WZ42	TTN	Q13557	CAMK2D	T1067	R1060T	1060	Missense	distal	-7	no	41.928	39.068	EPSD	COSMIC	37.605	Down-regulation
CAMK_CAMK2_CAMK2D_ST	Q8WZ42	TTN	Q13557	CAMK2D	T1238	Y1239S	1239	Missense	proximal	1	no	35.384	38.965	EPSD	COSMIC;GDSC;CCLE	37.605	Gain
CAMK_CAMK2_CAMK2D_ST	Q8WZ42	TTN	Q13557	CAMK2D	S1411	L1405P	1405	Missense	distal	-6	no	31.560	38.510	EPSD	COSMIC	37.605	Gain
CAMK_CAMK2_CAMK2D_ST	Q8WZ42	TTN	Q13557	CAMK2D	S1413	R1416C	1416	Missense	distal	3	no	37.564	40.255	EPSD	COSMIC	37.605	Gain
CAMK_CAMK2_CAMK2D_ST	Q8WZ42	TTN	Q13557	CAMK2D	S1413	R1408C	1408	Missense	distal	-5	no	37.564	37.863	EPSD	COSMIC	37.605	Gain
CAMK_CAMK2_CAMK2D_ST	Q8WZ42	TTN	Q13557	CAMK2D	S1418	R1416C	1416	Missense	proximal	-2	no	39.060	38.016	EPSD	COSMIC	37.605	Down-regulation
CAMK_CAMK2_CAMK2D_ST	Q8WZ42	TTN	Q13557	CAMK2D	S1418	S1413F	1413	Missense	distal	-5	no	39.060	40.255	EPSD	COSMIC	37.605	Up-regulation
CAMK_CAMK2_CAMK2D_ST	Q8WZ42	TTN	Q13557	CAMK2D	S1418	R1421W	1421	Missense	distal	3	no	39.060	26.961	EPSD	COSMIC	37.605	Loss
CAMK_CAMK2_CAMK2D_ST	Q8WZ42	TTN	Q13557	CAMK2D	S1465	G1471R	1471	Missense	distal	6	no	48.117	47.645	EPSD	COSMIC	37.605	Down-regulation
CAMK_CAMK2_CAMK2D_ST	Q8WZ42	TTN	Q13557	CAMK2D	T1546	I1541T	1541	Missense	distal	-5	no	38.235	39.394	EPSD	COSMIC	37.605	Up-regulation
CAMK_CAMK2_CAMK2D_ST	Q8WZ42	TTN	Q13557	CAMK2D	T1546	I1544V	1544	Missense	proximal	-2	no	38.235	37.998	EPSD	COSMIC	37.605	Down-regulation
CAMK_CAMK2_CAMK2D_ST	Q8WZ42	TTN	Q13557	CAMK2D	T1609	E1607G	1607	Missense	proximal	-2	no	50.647	50.918	EPSD	COSMIC	37.605	Up-regulation
CAMK_CAMK2_CAMK2D_ST	Q8WZ42	TTN	Q13557	CAMK2D	T1609	G1608R	1608	Missense	proximal	-1	no	50.647	52.603	EPSD	COSMIC	37.605	Up-regulation
CAMK_CAMK2_CAMK2D_ST	Q8WZ42	TTN	Q13557	CAMK2D	T1609	P1602T	1602	Missense	distal	-7	no	50.647	53.098	EPSD	COSMIC	37.605	Up-regulation
CAMK_CAMK2_CAMK2D_ST	Q8WZ42	TTN	Q13557	CAMK2D	T1609	G1611R	1611	Missense	proximal	2	no	50.647	47.761	EPSD	COSMIC	37.605	Down-regulation
CAMK_CAMK2_CAMK2D_ST	Q8WZ42	TTN	Q13557	CAMK2D	S1622	T1620I	1620	Missense	proximal	-2	no	37.251	38.229	EPSD	COSMIC	37.605	Gain
CAMK_CAMK2_CAMK2D_ST	Q8WZ42	TTN	Q13557	CAMK2D	S1799	D1796N	1796	Missense	distal	-3	no	25.828	42.812	EPSD	COSMIC	37.605	Gain
CAMK_CAMK2_CAMK2D_ST	Q8WZ42	TTN	Q13557	CAMK2D	S2072	M2075I	2075	Missense	distal	3	no	41.747	39.355	EPSD	COSMIC	37.605	Down-regulation
CAMK_CAMK2_CAMK2D_ST	Q8WZ42	TTN	Q13557	CAMK2D	S2072	K2068T	2068	Missense	distal	-4	no	41.747	42.749	EPSD	COSMIC	37.605	Up-regulation
CAMK_CAMK2_CAMK2D_ST	Q8WZ42	TTN	Q13557	CAMK2D	T2088	D2094N	2094	Missense	distal	6	no	40.025	42.122	EPSD	COSMIC	37.605	Up-regulation
CAMK_CAMK2_CAMK2D_ST	Q8WZ42	TTN	Q13557	CAMK2D	T2088	R2083T	2083	Missense	distal	-5	no	40.025	41.465	EPSD	COSMIC	37.605	Up-regulation
CAMK_CAMK2_CAMK2D_ST	Q8WZ42	TTN	Q13557	CAMK2D	T2088	G2092R	2092	Missense	distal	4	no	40.025	40.281	EPSD	COSMIC	37.605	Up-regulation
CAMK_CAMK2_CAMK2D_ST	Q8WZ42	TTN	Q13557	CAMK2D	T2088	I2084M	2084	Missense	distal	-4	no	40.025	38.272	EPSD	COSMIC	37.605	Down-regulation
CAMK_CAMK2_CAMK2D_ST	Q8WZ42	TTN	Q13557	CAMK2D	T2088	Q2087K	2087	Missense	proximal	-1	no	40.025	41.513	EPSD	COSMIC;CCLE	37.605	Up-regulation
CAMK_CAMK2_CAMK2D_ST	Q8WZ42	TTN	Q13557	CAMK2D	T2193	S2199R	2199	Missense	distal	6	no	44.487	45.527	EPSD	COSMIC	37.605	Up-regulation
CAMK_CAMK2_CAMK2D_ST	Q8WZ42	TTN	Q13557	CAMK2D	T2193	E2195K	2195	Missense	proximal	2	no	44.487	40.170	EPSD	COSMIC	37.605	Down-regulation
CAMK_CAMK2_CAMK2D_ST	Q8WZ42	TTN	Q13557	CAMK2D	T2193	C2196S	2196	Missense	distal	3	no	44.487	43.451	EPSD	COSMIC	37.605	Down-regulation
CAMK_CAMK2_CAMK2D_ST	Q8WZ42	TTN	Q13557	CAMK2D	T2193	S2199L	2199	Missense	distal	6	no	44.487	44.045	EPSD	COSMIC	37.605	Down-regulation
CAMK_CAMK2_CAMK2D_ST	Q8WZ42	TTN	Q13557	CAMK2D	T2193	D2189Y	2189	Missense	distal	-4	no	44.487	48.882	EPSD	COSMIC	37.605	Up-regulation
CAMK_CAMK2_CAMK2D_ST	Q8WZ42	TTN	Q13557	CAMK2D	S2308	E2305K	2305	Missense	distal	-3	no	4.039	38.323	EPSD	COSMIC	37.605	Gain
CAMK_CAMK2_CAMK2D_ST	Q8WZ42	TTN	Q13557	CAMK2D	T2507	Q2500H	2500	Missense	distal	-7	no	45.070	43.069	EPSD	COSMIC;GDSC;CCLE	37.605	Down-regulation
CAMK_CAMK2_CAMK2D_ST	Q8WZ42	TTN	Q13557	CAMK2D	T2507	E2512K	2512	Missense	distal	5	no	45.070	45.521	EPSD	COSMIC	37.605	Up-regulation
CAMK_CAMK2_CAMK2D_ST	Q8WZ42	TTN	Q13557	CAMK2D	T2507	G2513V	2513	Missense	distal	6	no	45.070	44.751	EPSD	COSMIC	37.605	Down-regulation
CAMK_CAMK2_CAMK2D_ST	Q8WZ42	TTN	Q13557	CAMK2D	T2507	V2503A	2503	Missense	distal	-4	no	45.070	43.619	EPSD	COSMIC	37.605	Down-regulation
CAMK_CAMK2_CAMK2D_ST	Q8WZ42	TTN	Q13557	CAMK2D	S2623	G2620R	2620	Missense	distal	-3	no	-0.043	42.914	EPSD	COSMIC	37.605	Gain
CAMK_CAMK2_CAMK2D_ST	Q8WZ42	TTN	Q13557	CAMK2D	S2749	E2751G	2751	Missense	proximal	2	no	45.043	46.738	EPSD	COSMIC	37.605	Up-regulation
CAMK_CAMK2_CAMK2D_ST	Q8WZ42	TTN	Q13557	CAMK2D	S2749	G2744R	2744	Missense	distal	-5	no	45.043	43.255	EPSD	COSMIC	37.605	Down-regulation
CAMK_CAMK2_CAMK2D_ST	Q8WZ42	TTN	Q13557	CAMK2D	T3119	R3120Q	3120	Missense	proximal	1	no	55.190	50.028	EPSD	COSMIC	37.605	Down-regulation
CAMK_CAMK2_CAMK2D_ST	Q8WZ42	TTN	Q13557	CAMK2D	T3119	L3114I	3114	Missense	distal	-5	no	55.190	55.259	EPSD	COSMIC	37.605	Up-regulation
CAMK_CAMK2_CAMK2D_ST	Q8WZ42	TTN	Q13557	CAMK2D	T3119	D3123H	3123	Missense	distal	4	no	55.190	55.192	EPSD	COSMIC	37.605	Up-regulation
CAMK_CAMK2_CAMK2D_ST	Q8WZ42	TTN	Q13557	CAMK2D	T3119	I3116M	3116	Missense	distal	-3	no	55.190	57.929	EPSD	COSMIC	37.605	Up-regulation
CAMK_CAMK2_CAMK2D_ST	Q8WZ42	TTN	Q13557	CAMK2D	S3208	R3211C	3211	Missense	distal	3	no	41.212	43.904	EPSD	COSMIC	37.605	Up-regulation
CAMK_CAMK2_CAMK2D_ST	Q8WZ42	TTN	Q13557	CAMK2D	S3208	H3203Y	3203	Missense	distal	-5	no	41.212	40.087	EPSD	COSMIC	37.605	Down-regulation
CAMK_CAMK2_CAMK2D_ST	Q8WZ42	TTN	Q13557	CAMK2D	S3208	H3203Q	3203	Missense	distal	-5	no	41.212	39.091	EPSD	COSMIC	37.605	Down-regulation
CAMK_CAMK2_CAMK2D_ST	Q8WZ42	TTN	Q13557	CAMK2D	S3208	D3214N	3214	Missense	distal	6	no	41.212	43.308	EPSD	COSMIC;GDSC;CCLE	37.605	Up-regulation
CAMK_CAMK2_CAMK2D_ST	Q8WZ42	TTN	Q13557	CAMK2D	T3249	T3249M	3249	Missense	central	0	yes	49.492	0.000	EPSD	COSMIC	37.605	Loss
CAMK_CAMK2_CAMK2D_ST	Q8WZ42	TTN	Q13557	CAMK2D	T3249	Q3246K	3246	Missense	distal	-3	no	49.492	49.307	EPSD	COSMIC	37.605	Down-regulation
CAMK_CAMK2_CAMK2D_ST	Q8WZ42	TTN	Q13557	CAMK2D	T3249	G3253D	3253	Missense	distal	4	no	49.492	48.173	EPSD	COSMIC	37.605	Down-regulation
CAMK_CAMK2_CAMK2D_ST	Q8WZ42	TTN	Q13557	CAMK2D	T3249	G3253S	3253	Missense	distal	4	no	49.492	49.586	EPSD	COSMIC	37.605	Up-regulation
CAMK_CAMK2_CAMK2D_ST	Q8WZ42	TTN	Q13557	CAMK2D	S3252	T3249M	3249	Missense	distal	-3	no	37.511	48.778	EPSD	COSMIC	37.605	Gain
CAMK_CAMK2_CAMK2D_ST	Q8WZ42	TTN	Q13557	CAMK2D	S3379	W3377C	3377	Missense	proximal	-2	no	41.287	41.428	EPSD	COSMIC	37.605	Up-regulation
CAMK_CAMK2_CAMK2D_ST	Q8WZ42	TTN	Q13557	CAMK2D	S3379	S3379G	3379	Missense	central	0	yes	41.287	0.000	EPSD	COSMIC	37.605	Loss
CAMK_CAMK2_CAMK2D_ST	Q8WZ42	TTN	Q13557	CAMK2D	S3458	K3453E	3453	Missense	distal	-5	no	37.764	38.940	EPSD	COSMIC	37.605	Up-regulation
CAMK_CAMK2_CAMK2D_ST	Q8WZ42	TTN	Q13557	CAMK2D	S3458	M3452I	3452	Missense	distal	-6	no	37.764	36.613	EPSD	COSMIC	37.605	Loss
CAMK_CAMK2_CAMK2D_ST	Q8WZ42	TTN	Q13557	CAMK2D	S3458	E3463D	3463	Missense	distal	5	no	37.764	36.658	EPSD	COSMIC	37.605	Loss
CAMK_CAMK2_CAMK2D_ST	Q8WZ42	TTN	Q13557	CAMK2D	T3934	Q3941E	3941	Missense	distal	7	no	53.679	54.826	EPSD	COSMIC	37.605	Up-regulation
CAMK_CAMK2_CAMK2D_ST	Q8WZ42	TTN	Q13557	CAMK2D	T3934	L3935P	3935	Missense	proximal	1	no	53.679	50.140	EPSD	COSMIC	37.605	Down-regulation
CAMK_CAMK2_CAMK2D_ST	Q8WZ42	TTN	Q13557	CAMK2D	T3934	R3929I	3929	Missense	distal	-5	no	53.679	53.959	EPSD	COSMIC	37.605	Up-regulation
CAMK_CAMK2_CAMK2D_ST	Q8WZ42	TTN	Q13557	CAMK2D	T3934	A3940S	3940	Missense	distal	6	no	53.679	50.716	EPSD	COSMIC;CCLE	37.605	Down-regulation
CAMK_CAMK2_CAMK2D_ST	Q8WZ42	TTN	Q13557	CAMK2D	S4065	R4058M	4058	Missense	distal	-7	no	48.809	49.163	EPSD	COSMIC	37.605	Up-regulation
CAMK_CAMK2_CAMK2D_ST	Q8WZ42	TTN	Q13557	CAMK2D	S4065	S4062F	4062	Missense	distal	-3	no	48.809	49.997	EPSD	COSMIC	37.605	Up-regulation
CAMK_CAMK2_CAMK2D_ST	Q8WZ42	TTN	Q13557	CAMK2D	S4068	S4062F	4062	Missense	distal	-6	no	44.994	44.454	EPSD	COSMIC	37.605	Down-regulation
CAMK_CAMK2_CAMK2D_ST	Q8WZ42	TTN	Q13557	CAMK2D	T4184	G4181R	4181	Missense	distal	-3	no	1.766	44.724	EPSD	COSMIC	37.605	Gain
CAMK_CAMK2_CAMK2D_ST	Q8WZ42	TTN	Q13557	CAMK2D	S4486	T4489A	4489	Missense	distal	3	no	41.087	54.214	EPSD	COSMIC;GDSC	37.605	Up-regulation
CAMK_CAMK2_CAMK2D_ST	Q8WZ42	TTN	Q13557	CAMK2D	S4486	T4489M	4489	Missense	distal	3	no	41.087	40.606	EPSD	COSMIC;GDSC	37.605	Down-regulation
CAMK_CAMK2_CAMK2D_ST	Q8WZ42	TTN	Q13557	CAMK2D	S4486	R4483K	4483	Missense	distal	-3	no	41.087	29.679	EPSD	COSMIC	37.605	Loss
CAMK_CAMK2_CAMK2D_ST	Q8WZ42	TTN	Q13557	CAMK2D	S4486	R4483G	4483	Missense	distal	-3	no	41.087	-1.871	EPSD	COSMIC	37.605	Loss
CAMK_CAMK2_CAMK2D_ST	Q8WZ42	TTN	Q13557	CAMK2D	S5083	F5090V	5090	Missense	distal	7	no	38.068	38.664	EPSD	COSMIC	37.605	Up-regulation
CAMK_CAMK2_CAMK2D_ST	Q8WZ42	TTN	Q13557	CAMK2D	S5083	A5082V	5082	Missense	proximal	-1	no	38.068	39.327	EPSD	COSMIC	37.605	Up-regulation
CAMK_CAMK2_CAMK2D_ST	Q8WZ42	TTN	Q13557	CAMK2D	S5083	D5084N	5084	Missense	proximal	1	no	38.068	41.748	EPSD	COSMIC	37.605	Up-regulation
CAMK_CAMK2_CAMK2D_ST	Q8WZ42	TTN	Q13557	CAMK2D	S5141	V5144A	5144	Missense	distal	3	no	30.969	52.201	EPSD	COSMIC	37.605	Gain
CAMK_CAMK2_CAMK2D_ST	Q8WZ42	TTN	Q13557	CAMK2D	T5155	K5153R	5153	Missense	proximal	-2	no	48.875	49.624	EPSD	COSMIC	37.605	Up-regulation
CAMK_CAMK2_CAMK2D_ST	Q8WZ42	TTN	Q13557	CAMK2D	T5155	S5154A	5154	Missense	proximal	-1	no	48.875	47.378	EPSD	COSMIC	37.605	Down-regulation
CAMK_CAMK2_CAMK2D_ST	Q8WZ42	TTN	Q13557	CAMK2D	T5155	L5162F	5162	Missense	distal	7	no	48.875	47.639	EPSD	COSMIC	37.605	Down-regulation
CAMK_CAMK2_CAMK2D_ST	Q8WZ42	TTN	Q13557	CAMK2D	T5155	S5154T	5154	Missense	proximal	-1	no	48.875	49.033	EPSD	COSMIC	37.605	Up-regulation
CAMK_CAMK2_CAMK2D_ST	Q8WZ42	TTN	Q13557	CAMK2D	T5155	V5150L	5150	Missense	distal	-5	no	48.875	47.393	EPSD	COSMIC	37.605	Down-regulation
CAMK_CAMK2_CAMK2D_ST	Q8WZ42	TTN	Q13557	CAMK2D	T5155	S5148L	5148	Missense	distal	-7	no	48.875	52.214	EPSD	COSMIC	37.605	Up-regulation
CAMK_CAMK2_CAMK2D_ST	Q8WZ42	TTN	Q13557	CAMK2D	T5155	V5150D	5150	Missense	distal	-5	no	48.875	48.843	EPSD	COSMIC	37.605	Down-regulation
CAMK_CAMK2_CAMK2D_ST	Q8WZ42	TTN	Q13557	CAMK2D	T5155	L5162V	5162	Missense	distal	7	no	48.875	48.235	EPSD	COSMIC	37.605	Down-regulation
CAMK_CAMK2_CAMK2D_ST	Q8WZ42	TTN	Q13557	CAMK2D	T5358	D5356Y	5356	Missense	proximal	-2	no	53.250	52.927	EPSD	COSMIC	37.605	Down-regulation
CAMK_CAMK2_CAMK2D_ST	Q8WZ42	TTN	Q13557	CAMK2D	T5358	G5363S	5363	Missense	distal	5	no	53.250	52.300	EPSD	COSMIC	37.605	Down-regulation
CAMK_CAMK2_CAMK2D_ST	Q8WZ42	TTN	Q13557	CAMK2D	T5358	D5356N	5356	Missense	proximal	-2	no	53.250	53.958	EPSD	COSMIC	37.605	Up-regulation
CAMK_CAMK2_CAMK2D_ST	Q8WZ42	TTN	Q13557	CAMK2D	T5358	R5361L	5361	Missense	distal	3	no	53.250	45.015	EPSD	COSMIC;CCLE	37.605	Down-regulation
CAMK_CAMK2_CAMK2D_ST	Q8WZ42	TTN	Q13557	CAMK2D	S5401	T5395A	5395	Missense	distal	-6	no	40.655	44.915	EPSD	COSMIC	37.605	Up-regulation
CAMK_CAMK2_CAMK2D_ST	Q8WZ42	TTN	Q13557	CAMK2D	S5401	R5406G	5406	Missense	distal	5	no	40.655	41.187	EPSD	COSMIC	37.605	Up-regulation
CAMK_CAMK2_CAMK2D_ST	Q8WZ42	TTN	Q13557	CAMK2D	S5401	R5406T	5406	Missense	distal	5	no	40.655	41.342	EPSD	COSMIC	37.605	Up-regulation
CAMK_CAMK2_CAMK2D_ST	Q8WZ42	TTN	Q13557	CAMK2D	T5568	K5571N	5571	Missense	distal	3	no	36.627	38.489	EPSD	COSMIC;CCLE	37.605	Gain
CAMK_CAMK2_CAMK2D_ST	Q8WZ42	TTN	Q13557	CAMK2D	S5603	I5600K	5600	Missense	distal	-3	no	36.499	38.194	EPSD	COSMIC	37.605	Gain
CAMK_CAMK2_CAMK2D_ST	Q8WZ42	TTN	Q13557	CAMK2D	S5603	L5598P	5598	Missense	distal	-5	no	36.499	37.859	EPSD	COSMIC	37.605	Gain
CAMK_CAMK2_CAMK2D_ST	Q8WZ42	TTN	Q13557	CAMK2D	S5603	K5606R	5606	Missense	distal	3	no	36.499	37.815	EPSD	COSMIC	37.605	Gain
CAMK_CAMK2_CAMK2D_ST	Q8WZ42	TTN	Q13557	CAMK2D	S5643	K5649N	5649	Missense	distal	6	no	38.223	39.121	EPSD	COSMIC	37.605	Up-regulation
CAMK_CAMK2_CAMK2D_ST	Q8WZ42	TTN	Q13557	CAMK2D	S5643	K5647M	5647	Missense	distal	4	no	38.223	37.434	EPSD	COSMIC	37.605	Loss
CAMK_CAMK2_CAMK2D_ST	Q8WZ42	TTN	Q13557	CAMK2D	T5690	G5687R	5687	Missense	distal	-3	no	3.375	46.333	EPSD	COSMIC	37.605	Gain
CAMK_CAMK2_CAMK2D_ST	Q8WZ42	TTN	Q13557	CAMK2D	S6117	S6115F	6115	Missense	proximal	-2	no	38.941	38.698	EPSD	COSMIC	37.605	Down-regulation
CAMK_CAMK2_CAMK2D_ST	Q8WZ42	TTN	Q13557	CAMK2D	S6117	S6115P	6115	Missense	proximal	-2	no	38.941	39.038	EPSD	COSMIC;CCLE	37.605	Up-regulation
CAMK_CAMK2_CAMK2D_ST	Q8WZ42	TTN	Q13557	CAMK2D	S6117	P6110T	6110	Missense	distal	-7	no	38.941	41.392	EPSD	COSMIC	37.605	Up-regulation
CAMK_CAMK2_CAMK2D_ST	Q8WZ42	TTN	Q13557	CAMK2D	S6117	S6111Y	6111	Missense	distal	-6	no	38.941	35.621	EPSD	COSMIC	37.605	Loss
CAMK_CAMK2_CAMK2D_ST	Q8WZ42	TTN	Q13557	CAMK2D	S6124	R6126I	6126	Missense	proximal	2	no	44.201	45.828	EPSD	COSMIC	37.605	Up-regulation
CAMK_CAMK2_CAMK2D_ST	Q8WZ42	TTN	Q13557	CAMK2D	S6124	R6126M	6126	Missense	proximal	2	no	44.201	42.085	EPSD	COSMIC	37.605	Down-regulation
CAMK_CAMK2_CAMK2D_ST	Q8WZ42	TTN	Q13557	CAMK2D	S6124	R6126S	6126	Missense	proximal	2	no	44.201	45.007	EPSD	COSMIC	37.605	Up-regulation
CAMK_CAMK2_CAMK2D_ST	Q8WZ42	TTN	Q13557	CAMK2D	S6205	S6207G	6207	Missense	proximal	2	no	39.253	41.333	EPSD	COSMIC	37.605	Up-regulation
CAMK_CAMK2_CAMK2D_ST	Q8WZ42	TTN	Q13557	CAMK2D	S6205	G6201V	6201	Missense	distal	-4	no	39.253	42.367	EPSD	COSMIC	37.605	Up-regulation
CAMK_CAMK2_CAMK2D_ST	Q8WZ42	TTN	Q13557	CAMK2D	T6508	G6512S	6512	Missense	distal	4	no	38.257	38.351	EPSD	COSMIC	37.605	Up-regulation
CAMK_CAMK2_CAMK2D_ST	Q8WZ42	TTN	Q13557	CAMK2D	T6508	L6504F	6504	Missense	distal	-4	no	38.257	37.004	EPSD	COSMIC	37.605	Loss
CAMK_CAMK2_CAMK2D_ST	Q8WZ42	TTN	Q13557	CAMK2D	T6508	H6502Y	6502	Missense	distal	-6	no	38.257	34.015	EPSD	COSMIC	37.605	Loss
CAMK_CAMK2_CAMK2D_ST	Q8WZ42	TTN	Q13557	CAMK2D	T6508	L6504I	6504	Missense	distal	-4	no	38.257	39.932	EPSD	COSMIC	37.605	Up-regulation
CAMK_CAMK2_CAMK2D_ST	Q8WZ42	TTN	Q13557	CAMK2D	T6508	D6510V	6510	Missense	proximal	2	no	38.257	25.951	EPSD	COSMIC;CCLE	37.605	Loss
CAMK_CAMK2_CAMK2D_ST	Q8WZ42	TTN	Q13557	CAMK2D	S6687	R6689G	6689	Missense	proximal	2	no	36.190	39.077	EPSD	COSMIC	37.605	Gain
CAMK_CAMK2_CAMK2D_ST	Q8WZ42	TTN	Q13557	CAMK2D	S6687	N6683Y	6683	Missense	distal	-4	no	36.190	41.624	EPSD	COSMIC	37.605	Gain
CAMK_CAMK2_CAMK2D_ST	Q8WZ42	TTN	Q13557	CAMK2D	S6692	L6691V	6691	Missense	proximal	-1	no	54.175	55.370	EPSD	COSMIC	37.605	Up-regulation
CAMK_CAMK2_CAMK2D_ST	Q8WZ42	TTN	Q13557	CAMK2D	S6692	A6698S	6698	Missense	distal	6	no	54.175	51.213	EPSD	COSMIC	37.605	Down-regulation
CAMK_CAMK2_CAMK2D_ST	Q8WZ42	TTN	Q13557	CAMK2D	S6692	D6697N	6697	Missense	distal	5	no	54.175	56.255	EPSD	COSMIC	37.605	Up-regulation
CAMK_CAMK2_CAMK2D_ST	Q8WZ42	TTN	Q13557	CAMK2D	S6692	R6689G	6689	Missense	distal	-3	no	54.175	11.217	EPSD	COSMIC	37.605	Loss
CAMK_CAMK2_CAMK2D_ST	Q8WZ42	TTN	Q13557	CAMK2D	S6923	S6929T	6929	Missense	distal	6	no	40.074	39.444	EPSD	COSMIC	37.605	Down-regulation
CAMK_CAMK2_CAMK2D_ST	Q8WZ42	TTN	Q13557	CAMK2D	S6923	S6929Y	6929	Missense	distal	6	no	40.074	39.742	EPSD	COSMIC	37.605	Down-regulation
CAMK_CAMK2_CAMK2D_ST	Q8WZ42	TTN	Q13557	CAMK2D	S6923	I6930T	6930	Missense	distal	7	no	40.074	40.669	EPSD	COSMIC	37.605	Up-regulation
CAMK_CAMK2_CAMK2D_ST	Q8WZ42	TTN	Q13557	CAMK2D	S6923	D6921N	6921	Missense	proximal	-2	no	40.074	40.782	EPSD	COSMIC	37.605	Up-regulation
CAMK_CAMK2_CAMK2D_ST	Q8WZ42	TTN	Q13557	CAMK2D	T6954	D6949Y	6949	Missense	distal	-5	no	44.547	43.667	EPSD	COSMIC	37.605	Down-regulation
CAMK_CAMK2_CAMK2D_ST	Q8WZ42	TTN	Q13557	CAMK2D	T6954	K6947R	6947	Missense	distal	-7	no	44.547	42.958	EPSD	COSMIC	37.605	Down-regulation
CAMK_CAMK2_CAMK2D_ST	Q8WZ42	TTN	Q13557	CAMK2D	S6956	D6949Y	6949	Missense	distal	-7	no	36.488	40.291	EPSD	COSMIC	37.605	Gain
CAMK_CAMK2_CAMK2D_ST	Q8WZ42	TTN	Q13557	CAMK2D	T7230	N7235K	7235	Missense	distal	5	no	43.087	42.564	EPSD	COSMIC	37.605	Down-regulation
CAMK_CAMK2_CAMK2D_ST	Q8WZ42	TTN	Q13557	CAMK2D	T7230	R7228Q	7228	Missense	proximal	-2	no	43.087	42.569	EPSD	COSMIC	37.605	Down-regulation
CAMK_CAMK2_CAMK2D_ST	Q8WZ42	TTN	Q13557	CAMK2D	T7230	R7228L	7228	Missense	proximal	-2	no	43.087	42.179	EPSD	COSMIC	37.605	Down-regulation
CAMK_CAMK2_CAMK2D_ST	Q8WZ42	TTN	Q13557	CAMK2D	S7308	G7306R	7306	Missense	proximal	-2	no	40.027	40.744	EPSD	COSMIC	37.605	Up-regulation
CAMK_CAMK2_CAMK2D_ST	Q8WZ42	TTN	Q13557	CAMK2D	S7308	I7315V	7315	Missense	distal	7	no	40.027	39.770	EPSD	COSMIC	37.605	Down-regulation
CAMK_CAMK2_CAMK2D_ST	Q8WZ42	TTN	Q13557	CAMK2D	S7330	H7333Y	7333	Missense	distal	3	no	32.580	47.229	EPSD	COSMIC;CCLE	37.605	Gain
CAMK_CAMK2_CAMK2D_ST	Q8WZ42	TTN	Q13557	CAMK2D	S7485	P7478S	7478	Missense	distal	-7	no	34.602	37.853	EPSD	COSMIC	37.605	Gain
CAMK_CAMK2_CAMK2D_ST	Q8WZ42	TTN	Q13557	CAMK2D	S7485	D7486H	7486	Missense	proximal	1	no	34.602	38.011	EPSD	COSMIC	37.605	Gain
CAMK_CAMK2_CAMK2D_ST	Q8WZ42	TTN	Q13557	CAMK2D	S7613	E7611Q	7611	Missense	proximal	-2	no	45.107	45.576	EPSD	COSMIC	37.605	Up-regulation
CAMK_CAMK2_CAMK2D_ST	Q8WZ42	TTN	Q13557	CAMK2D	S7613	D7608H	7608	Missense	distal	-5	no	45.107	45.351	EPSD	COSMIC	37.605	Up-regulation
CAMK_CAMK2_CAMK2D_ST	Q8WZ42	TTN	Q13557	CAMK2D	S7613	K7607R	7607	Missense	distal	-6	no	45.107	47.518	EPSD	COSMIC	37.605	Up-regulation
CAMK_CAMK2_CAMK2D_ST	Q8WZ42	TTN	Q13557	CAMK2D	S7613	A7614E	7614	Missense	proximal	1	no	45.107	49.938	EPSD	COSMIC	37.605	Up-regulation
CAMK_CAMK2_CAMK2D_ST	Q8WZ42	TTN	Q13557	CAMK2D	S7649	K7652T	7652	Missense	distal	3	no	38.831	35.139	EPSD	COSMIC	37.605	Loss
CAMK_CAMK2_CAMK2D_ST	Q8WZ42	TTN	Q13557	CAMK2D	S7649	K7652R	7652	Missense	distal	3	no	38.831	40.147	EPSD	COSMIC	37.605	Up-regulation
CAMK_CAMK2_CAMK2D_ST	Q8WZ42	TTN	Q13557	CAMK2D	S7649	C7655Y	7655	Missense	distal	6	no	38.831	38.136	EPSD	COSMIC	37.605	Down-regulation
CAMK_CAMK2_CAMK2D_ST	Q8WZ42	TTN	Q13557	CAMK2D	S7649	N7654S	7654	Missense	distal	5	no	38.831	38.335	EPSD	COSMIC;CCLE	37.605	Down-regulation
CAMK_CAMK2_CAMK2D_ST	Q8WZ42	TTN	Q13557	CAMK2D	S7649	F7644L	7644	Missense	distal	-5	no	38.831	36.899	EPSD	COSMIC	37.605	Loss
CAMK_CAMK2_CAMK2D_ST	Q8WZ42	TTN	Q13557	CAMK2D	S7649	G7651S	7651	Missense	proximal	2	no	38.831	36.751	EPSD	COSMIC	37.605	Loss
CAMK_CAMK2_CAMK2D_ST	Q8WZ42	TTN	Q13557	CAMK2D	S7989	K7982E	7982	Missense	distal	-7	no	51.310	45.043	EPSD	COSMIC	37.605	Down-regulation
CAMK_CAMK2_CAMK2D_ST	Q8WZ42	TTN	Q13557	CAMK2D	T8197	A8194V	8194	Missense	distal	-3	no	25.457	39.030	EPSD	COSMIC	37.605	Gain
CAMK_CAMK2_CAMK2D_ST	Q8WZ42	TTN	Q13557	CAMK2D	S8426	V8432I	8432	Missense	distal	6	no	40.779	39.031	EPSD	COSMIC	37.605	Down-regulation
CAMK_CAMK2_CAMK2D_ST	Q8WZ42	TTN	Q13557	CAMK2D	S8426	V8431A	8431	Missense	distal	5	no	40.779	40.991	EPSD	COSMIC	37.605	Up-regulation
CAMK_CAMK2_CAMK2D_ST	Q8WZ42	TTN	Q13557	CAMK2D	S8426	L8425P	8425	Missense	proximal	-1	no	40.779	39.004	EPSD	COSMIC	37.605	Down-regulation
CAMK_CAMK2_CAMK2D_ST	Q8WZ42	TTN	Q13557	CAMK2D	S8740	L8742P	8742	Missense	proximal	2	no	40.516	36.647	EPSD	COSMIC	37.605	Loss
CAMK_CAMK2_CAMK2D_ST	Q8WZ42	TTN	Q13557	CAMK2D	S8740	V8733F	8733	Missense	distal	-7	no	40.516	40.504	EPSD	COSMIC	37.605	Down-regulation
CAMK_CAMK2_CAMK2D_ST	Q8WZ42	TTN	Q13557	CAMK2D	S8805	R8800K	8800	Missense	distal	-5	no	38.996	39.021	EPSD	COSMIC	37.605	Up-regulation
CAMK_CAMK2_CAMK2D_ST	Q8WZ42	TTN	Q13557	CAMK2D	T8836	P8837L	8837	Missense	proximal	1	no	37.043	40.582	EPSD	COSMIC	37.605	Gain
CAMK_CAMK2_CAMK2D_ST	Q8WZ42	TTN	Q13557	CAMK2D	S9177	P9175L	9175	Missense	proximal	-2	no	38.500	38.027	EPSD	COSMIC	37.605	Down-regulation
CAMK_CAMK2_CAMK2D_ST	Q8WZ42	TTN	Q13557	CAMK2D	S9177	R9172Q	9172	Missense	distal	-5	no	38.500	38.284	EPSD	COSMIC	37.605	Down-regulation
CAMK_CAMK2_CAMK2D_ST	Q8WZ42	TTN	Q13557	CAMK2D	T9189	E9190K	9190	Missense	proximal	1	no	43.771	44.245	EPSD	COSMIC	37.605	Up-regulation
CAMK_CAMK2_CAMK2D_ST	Q8WZ42	TTN	Q13557	CAMK2D	T9189	S9193Y	9193	Missense	distal	4	no	43.771	43.372	EPSD	COSMIC	37.605	Down-regulation
CAMK_CAMK2_CAMK2D_ST	Q8WZ42	TTN	Q13557	CAMK2D	T9189	E9187A	9187	Missense	proximal	-2	no	43.771	43.869	EPSD	COSMIC;CCLE	37.605	Up-regulation
CAMK_CAMK2_CAMK2D_ST	Q8WZ42	TTN	Q13557	CAMK2D	T9189	E9190D	9190	Missense	proximal	1	no	43.771	39.844	EPSD	COSMIC	37.605	Down-regulation
CAMK_CAMK2_CAMK2D_ST	Q8WZ42	TTN	Q13557	CAMK2D	S9193	E9190K	9190	Missense	distal	-3	no	5.443	39.726	EPSD	COSMIC	37.605	Gain
CAMK_CAMK2_CAMK2D_ST	Q8WZ42	TTN	Q13557	CAMK2D	S9578	T9580I	9580	Missense	proximal	2	no	37.286	41.378	EPSD	COSMIC	37.605	Gain
CAMK_CAMK2_CAMK2D_ST	Q8WZ42	TTN	Q13557	CAMK2D	S9633	D9628Y	9628	Missense	distal	-5	no	39.074	38.194	EPSD	COSMIC	37.605	Down-regulation
CAMK_CAMK2_CAMK2D_ST	Q8WZ42	TTN	Q13557	CAMK2D	S9633	S9633N	9633	Missense	central	0	yes	39.074	0.000	EPSD	COSMIC	37.605	Loss
CAMK_CAMK2_CAMK2D_ST	Q8WZ42	TTN	Q13557	CAMK2D	S9633	E9631K	9631	Missense	proximal	-2	no	39.074	39.312	EPSD	COSMIC	37.605	Up-regulation
CAMK_CAMK2_CAMK2D_ST	Q8WZ42	TTN	Q13557	CAMK2D	T9970	K9972E	9972	Missense	proximal	2	no	34.407	38.724	EPSD	COSMIC	37.605	Gain
CAMK_CAMK2_CAMK2D_ST	Q8WZ42	TTN	Q13557	CAMK2D	T10388	F10395I	10395	Missense	distal	7	no	37.511	38.364	EPSD	COSMIC	37.605	Gain
CAMK_CAMK2_CAMK2D_ST	Q8WZ42	TTN	Q13557	CAMK2D	S10402	E10399K	10399	Missense	distal	-3	no	9.461	43.744	EPSD	COSMIC	37.605	Gain
CAMK_CAMK2_CAMK2D_ST	Q8WZ42	TTN	Q13557	CAMK2D	T10581	P10586Q	10586	Missense	distal	5	no	53.675	53.261	EPSD	COSMIC	37.605	Down-regulation
CAMK_CAMK2_CAMK2D_ST	Q8WZ42	TTN	Q13557	CAMK2D	T10581	V10580L	10580	Missense	proximal	-1	no	53.675	52.480	EPSD	COSMIC	37.605	Down-regulation
CAMK_CAMK2_CAMK2D_ST	Q8WZ42	TTN	Q13557	CAMK2D	T10581	P10587S	10587	Missense	distal	6	no	53.675	47.773	EPSD	COSMIC;CCLE	37.605	Down-regulation
CAMK_CAMK2_CAMK2D_ST	Q8WZ42	TTN	Q13557	CAMK2D	T10581	P10587Q	10587	Missense	distal	6	no	53.675	51.364	EPSD	COSMIC	37.605	Down-regulation
CAMK_CAMK2_CAMK2D_ST	Q8WZ42	TTN	Q13557	CAMK2D	T10581	V10578L	10578	Missense	distal	-3	no	53.675	44.223	EPSD	COSMIC	37.605	Down-regulation
CAMK_CAMK2_CAMK2D_ST	Q8WZ42	TTN	Q13557	CAMK2D	T10658	A10656V	10656	Missense	proximal	-2	no	53.104	53.378	EPSD	COSMIC	37.605	Up-regulation
CAMK_CAMK2_CAMK2D_ST	Q8WZ42	TTN	Q13557	CAMK2D	T10658	E10662K	10662	Missense	distal	4	no	53.104	53.560	EPSD	COSMIC	37.605	Up-regulation
CAMK_CAMK2_CAMK2D_ST	Q8WZ42	TTN	Q13557	CAMK2D	T10658	T10658I	10658	Missense	central	0	yes	53.104	0.000	EPSD	COSMIC	37.605	Loss
CAMK_CAMK2_CAMK2D_ST	Q8WZ42	TTN	Q13557	CAMK2D	S10665	E10662K	10662	Missense	distal	-3	no	4.531	38.815	EPSD	COSMIC	37.605	Gain
CAMK_CAMK2_CAMK2D_ST	Q8WZ42	TTN	Q13557	CAMK2D	S10781	R10785H	10785	Missense	distal	4	no	39.141	37.568	EPSD	COSMIC	37.605	Loss
CAMK_CAMK2_CAMK2D_ST	Q8WZ42	TTN	Q13557	CAMK2D	S10781	R10779H	10779	Missense	proximal	-2	no	39.141	38.249	EPSD	COSMIC	37.605	Down-regulation
CAMK_CAMK2_CAMK2D_ST	Q8WZ42	TTN	Q13557	CAMK2D	S10781	K10787N	10787	Missense	distal	6	no	39.141	40.039	EPSD	COSMIC	37.605	Up-regulation
CAMK_CAMK2_CAMK2D_ST	Q8WZ42	TTN	Q13557	CAMK2D	S10781	E10786D	10786	Missense	distal	5	no	39.141	38.035	EPSD	COSMIC	37.605	Down-regulation
CAMK_CAMK2_CAMK2D_ST	Q8WZ42	TTN	Q13557	CAMK2D	S11503	E11502K	11502	Missense	proximal	-1	no	48.031	48.425	EPSD	COSMIC	37.605	Up-regulation
CAMK_CAMK2_CAMK2D_ST	Q8WZ42	TTN	Q13557	CAMK2D	S11503	P11505L	11505	Missense	proximal	2	no	48.031	51.900	EPSD	COSMIC	37.605	Up-regulation
CAMK_CAMK2_CAMK2D_ST	Q8WZ42	TTN	Q13557	CAMK2D	S11503	P11505T	11505	Missense	proximal	2	no	48.031	47.180	EPSD	COSMIC	37.605	Down-regulation
CAMK_CAMK2_CAMK2D_ST	Q8WZ42	TTN	Q13557	CAMK2D	S11503	P11501S	11501	Missense	proximal	-2	no	48.031	47.934	EPSD	COSMIC	37.605	Down-regulation
CAMK_CAMK2_CAMK2D_ST	Q8WZ42	TTN	Q13557	CAMK2D	S11878	R11883S	11883	Missense	distal	5	no	73.026	72.608	EPSD;PhosphoSitePlus	COSMIC	37.605	Down-regulation
CAMK_CAMK2_CAMK2D_ST	Q8WZ42	TTN	Q13557	CAMK2D	S11878	R11883H	11883	Missense	distal	5	no	73.026	73.828	EPSD;PhosphoSitePlus	COSMIC	37.605	Up-regulation
CAMK_CAMK2_CAMK2D_ST	Q8WZ42	TTN	Q13557	CAMK2D	S11878	E11885V	11885	Missense	distal	7	no	73.026	72.703	EPSD;PhosphoSitePlus	COSMIC	37.605	Down-regulation
CAMK_CAMK2_CAMK2D_ST	Q8WZ42	TTN	Q13557	CAMK2D	S11878	R11883K	11883	Missense	distal	5	no	73.026	72.581	EPSD;PhosphoSitePlus	COSMIC	37.605	Down-regulation
CAMK_CAMK2_CAMK2D_ST	Q8WZ42	TTN	Q13557	CAMK2D	S11878	E11885G	11885	Missense	distal	7	no	73.026	72.385	EPSD;PhosphoSitePlus	COSMIC	37.605	Down-regulation
CAMK_CAMK2_CAMK2D_ST	Q8WZ42	TTN	Q13557	CAMK2D	S11878	E11873K	11873	Missense	distal	-5	no	73.026	71.850	EPSD;PhosphoSitePlus	COSMIC	37.605	Down-regulation
CAMK_CAMK2_CAMK2D_ST	Q8WZ42	TTN	Q13557	CAMK2D	S11878	E11885K	11885	Missense	distal	7	no	73.026	73.105	EPSD;PhosphoSitePlus	COSMIC	37.605	Up-regulation
CAMK_CAMK2_CAMK2D_ST	Q8WZ42	TTN	Q13557	CAMK2D	S11878	V11879F	11879	Missense	proximal	1	no	73.026	79.412	EPSD;PhosphoSitePlus	COSMIC	37.605	Up-regulation
CAMK_CAMK2_CAMK2D_ST	Q8WZ42	TTN	Q13557	CAMK2D	T11969	P11966R	11966	Missense	distal	-3	no	-27.703	41.727	EPSD	COSMIC	37.605	Gain
CAMK_CAMK2_CAMK2D_ST	Q8WZ42	TTN	Q13557	CAMK2D	S12022	P12027S	12027	Missense	distal	5	no	75.535	72.683	PhosphoSitePlus;EPSD	COSMIC	37.605	Down-regulation
CAMK_CAMK2_CAMK2D_ST	Q8WZ42	TTN	Q13557	CAMK2D	S12022	P12020S	12020	Missense	proximal	-2	no	75.535	75.438	PhosphoSitePlus;EPSD	COSMIC	37.605	Down-regulation
CAMK_CAMK2_CAMK2D_ST	Q8WZ42	TTN	Q13557	CAMK2D	S12022	P12028S	12028	Missense	distal	6	no	75.535	69.634	PhosphoSitePlus;EPSD	COSMIC	37.605	Down-regulation
CAMK_CAMK2_CAMK2D_ST	Q8WZ42	TTN	Q13557	CAMK2D	S12022	R12015K	12015	Missense	distal	-7	no	75.535	77.124	PhosphoSitePlus;EPSD	COSMIC	37.605	Up-regulation
CAMK_CAMK2_CAMK2D_ST	Q8WZ42	TTN	Q13557	CAMK2D	S12022	K12017N	12017	Missense	distal	-5	no	75.535	77.213	PhosphoSitePlus;EPSD	COSMIC	37.605	Up-regulation
CAMK_CAMK2_CAMK2D_ST	Q8WZ42	TTN	Q13557	CAMK2D	S12022	G12021A	12021	Missense	proximal	-1	no	75.535	74.842	PhosphoSitePlus;EPSD	COSMIC	37.605	Down-regulation
CAMK_CAMK2_CAMK2D_ST	Q8WZ42	TTN	Q13557	CAMK2D	T12334	E12331K	12331	Missense	distal	-3	no	15.435	49.718	EPSD	COSMIC;GDSC	37.605	Gain
CAMK_CAMK2_CAMK2D_ST	Q8WZ42	TTN	Q13557	CAMK2D	S12902	T12909N	12909	Missense	distal	7	no	53.372	52.463	EPSD	COSMIC	37.605	Down-regulation
CAMK_CAMK2_CAMK2D_ST	Q8WZ42	TTN	Q13557	CAMK2D	S12902	M12903V	12903	Missense	proximal	1	no	53.372	48.497	EPSD	COSMIC	37.605	Down-regulation
CAMK_CAMK2_CAMK2D_ST	Q8WZ42	TTN	Q13557	CAMK2D	S12902	R12899G	12899	Missense	distal	-3	no	53.372	10.414	EPSD	COSMIC	37.605	Loss
CAMK_CAMK2_CAMK2D_ST	Q8WZ42	TTN	Q13557	CAMK2D	S12911	S12918F	12918	Missense	distal	7	no	37.323	37.973	EPSD	COSMIC	37.605	Gain
CAMK_CAMK2_CAMK2D_ST	Q8WZ42	TTN	Q13557	CAMK2D	S12911	T12909N	12909	Missense	proximal	-2	no	37.323	38.407	EPSD	COSMIC	37.605	Gain
CAMK_CAMK2_CAMK2D_ST	Q8WZ42	TTN	Q13557	CAMK2D	S13501	E13494K	13494	Missense	distal	-7	no	34.817	41.084	EPSD	COSMIC	37.605	Gain
CAMK_CAMK2_CAMK2D_ST	Q8WZ42	TTN	Q13557	CAMK2D	T13679	K13675I	13675	Missense	distal	-4	no	38.589	38.237	EPSD	COSMIC	37.605	Down-regulation
CAMK_CAMK2_CAMK2D_ST	Q8WZ42	TTN	Q13557	CAMK2D	T13679	V13678M	13678	Missense	proximal	-1	no	38.589	36.423	EPSD	COSMIC	37.605	Loss
CAMK_CAMK2_CAMK2D_ST	Q8WZ42	TTN	Q13557	CAMK2D	S13802	I13807V	13807	Missense	distal	5	no	38.601	39.847	EPSD	COSMIC	37.605	Up-regulation
CAMK_CAMK2_CAMK2D_ST	Q8WZ42	TTN	Q13557	CAMK2D	S13802	K13809N	13809	Missense	distal	7	no	38.601	38.142	EPSD	COSMIC;CCLE	37.605	Down-regulation
CAMK_CAMK2_CAMK2D_ST	Q8WZ42	TTN	Q13557	CAMK2D	T14099	V14097F	14097	Missense	proximal	-2	no	44.513	44.354	EPSD	COSMIC	37.605	Down-regulation
CAMK_CAMK2_CAMK2D_ST	Q8WZ42	TTN	Q13557	CAMK2D	T14099	R14094I	14094	Missense	distal	-5	no	44.513	44.794	EPSD	COSMIC	37.605	Up-regulation
CAMK_CAMK2_CAMK2D_ST	Q8WZ42	TTN	Q13557	CAMK2D	T14099	P14102T	14102	Missense	distal	3	no	44.513	39.121	EPSD	COSMIC	37.605	Down-regulation
CAMK_CAMK2_CAMK2D_ST	Q8WZ42	TTN	Q13557	CAMK2D	T14099	V14097I	14097	Missense	proximal	-2	no	44.513	44.750	EPSD	COSMIC	37.605	Up-regulation
CAMK_CAMK2_CAMK2D_ST	Q8WZ42	TTN	Q13557	CAMK2D	T14099	G14100R	14100	Missense	proximal	1	no	44.513	49.268	EPSD	COSMIC	37.605	Up-regulation
CAMK_CAMK2_CAMK2D_ST	Q8WZ42	TTN	Q13557	CAMK2D	S14345	P14338T	14338	Missense	distal	-7	no	35.590	38.041	EPSD	COSMIC	37.605	Gain
CAMK_CAMK2_CAMK2D_ST	Q8WZ42	TTN	Q13557	CAMK2D	S14384	P14383T	14383	Missense	proximal	-1	no	35.821	39.188	EPSD	COSMIC	37.605	Gain
CAMK_CAMK2_CAMK2D_ST	Q8WZ42	TTN	Q13557	CAMK2D	T14460	E14455K	14455	Missense	distal	-5	no	40.213	39.037	EPSD	COSMIC	37.605	Down-regulation
CAMK_CAMK2_CAMK2D_ST	Q8WZ42	TTN	Q13557	CAMK2D	T14460	R14458W	14458	Missense	proximal	-2	no	40.213	39.027	EPSD	COSMIC	37.605	Down-regulation
CAMK_CAMK2_CAMK2D_ST	Q8WZ42	TTN	Q13557	CAMK2D	T14460	S14457I	14457	Missense	distal	-3	no	40.213	43.284	EPSD	COSMIC	37.605	Up-regulation
CAMK_CAMK2_CAMK2D_ST	Q8WZ42	TTN	Q13557	CAMK2D	T14633	G14626R	14626	Missense	distal	-7	no	39.528	44.955	EPSD	COSMIC	37.605	Up-regulation
CAMK_CAMK2_CAMK2D_ST	Q8WZ42	TTN	Q13557	CAMK2D	T14633	T14640I	14640	Missense	distal	7	no	39.528	38.934	EPSD	COSMIC	37.605	Down-regulation
CAMK_CAMK2_CAMK2D_ST	Q8WZ42	TTN	Q13557	CAMK2D	T14633	L14637P	14637	Missense	distal	4	no	39.528	38.716	EPSD	COSMIC	37.605	Down-regulation
CAMK_CAMK2_CAMK2D_ST	Q8WZ42	TTN	Q13557	CAMK2D	T14633	L14627F	14627	Missense	distal	-6	no	39.528	46.290	EPSD	COSMIC	37.605	Up-regulation
CAMK_CAMK2_CAMK2D_ST	Q8WZ42	TTN	Q13557	CAMK2D	T14633	T14640K	14640	Missense	distal	7	no	39.528	39.079	EPSD	COSMIC	37.605	Down-regulation
CAMK_CAMK2_CAMK2D_ST	Q8WZ42	TTN	Q13557	CAMK2D	T14674	T14676A	14676	Missense	proximal	2	no	37.612	42.263	EPSD	COSMIC	37.605	Up-regulation
CAMK_CAMK2_CAMK2D_ST	Q8WZ42	TTN	Q13557	CAMK2D	T14674	S14673F	14673	Missense	proximal	-1	no	37.612	34.340	EPSD	COSMIC	37.605	Loss
CAMK_CAMK2_CAMK2D_ST	Q8WZ42	TTN	Q13557	CAMK2D	T14674	I14677T	14677	Missense	distal	3	no	37.612	40.485	EPSD	COSMIC	37.605	Up-regulation
CAMK_CAMK2_CAMK2D_ST	Q8WZ42	TTN	Q13557	CAMK2D	T14674	K14671Q	14671	Missense	distal	-3	no	37.612	37.797	EPSD	COSMIC	37.605	Up-regulation
CAMK_CAMK2_CAMK2D_ST	Q8WZ42	TTN	Q13557	CAMK2D	S14680	T14676A	14676	Missense	distal	-4	no	48.343	47.927	EPSD	COSMIC	37.605	Down-regulation
CAMK_CAMK2_CAMK2D_ST	Q8WZ42	TTN	Q13557	CAMK2D	S14680	S14673F	14673	Missense	distal	-7	no	48.343	45.678	EPSD	COSMIC	37.605	Down-regulation
CAMK_CAMK2_CAMK2D_ST	Q8WZ42	TTN	Q13557	CAMK2D	S14680	I14677T	14677	Missense	distal	-3	no	48.343	39.815	EPSD	COSMIC	37.605	Down-regulation
CAMK_CAMK2_CAMK2D_ST	Q8WZ42	TTN	Q13557	CAMK2D	S14680	R14682I	14682	Missense	proximal	2	no	48.343	49.970	EPSD	COSMIC	37.605	Up-regulation
CAMK_CAMK2_CAMK2D_ST	Q8WZ42	TTN	Q13557	CAMK2D	S15263	N15262D	15262	Missense	proximal	-1	no	38.902	36.917	EPSD	COSMIC	37.605	Loss
CAMK_CAMK2_CAMK2D_ST	Q8WZ42	TTN	Q13557	CAMK2D	S15263	P15265T	15265	Missense	proximal	2	no	38.902	38.051	EPSD	COSMIC	37.605	Down-regulation
CAMK_CAMK2_CAMK2D_ST	Q8WZ42	TTN	Q13557	CAMK2D	S15263	R15264H	15264	Missense	proximal	1	no	38.902	32.632	EPSD	COSMIC	37.605	Loss
CAMK_CAMK2_CAMK2D_ST	Q8WZ42	TTN	Q13557	CAMK2D	T15466	K15468Q	15468	Missense	proximal	2	no	37.701	41.579	EPSD	COSMIC	37.605	Up-regulation
CAMK_CAMK2_CAMK2D_ST	Q8WZ42	TTN	Q13557	CAMK2D	T15466	G15459D	15459	Missense	distal	-7	no	37.701	38.132	EPSD	COSMIC	37.605	Up-regulation
CAMK_CAMK2_CAMK2D_ST	Q8WZ42	TTN	Q13557	CAMK2D	T15466	L15470I	15470	Missense	distal	4	no	37.701	36.791	EPSD	COSMIC	37.605	Loss
CAMK_CAMK2_CAMK2D_ST	Q8WZ42	TTN	Q13557	CAMK2D	S15682	D15684G	15684	Missense	proximal	2	no	41.614	35.883	EPSD	COSMIC	37.605	Loss
CAMK_CAMK2_CAMK2D_ST	Q8WZ42	TTN	Q13557	CAMK2D	S15682	R15680C	15680	Missense	proximal	-2	no	41.614	40.569	EPSD	COSMIC;CCLE	37.605	Down-regulation
CAMK_CAMK2_CAMK2D_ST	Q8WZ42	TTN	Q13557	CAMK2D	S15682	K15687T	15687	Missense	distal	5	no	41.614	42.746	EPSD	COSMIC	37.605	Up-regulation
CAMK_CAMK2_CAMK2D_ST	Q8WZ42	TTN	Q13557	CAMK2D	S15682	G15689A	15689	Missense	distal	7	no	41.614	41.986	EPSD	COSMIC	37.605	Up-regulation
CAMK_CAMK2_CAMK2D_ST	Q8WZ42	TTN	Q13557	CAMK2D	S15691	L15693I	15693	Missense	proximal	2	no	49.674	49.046	EPSD	COSMIC	37.605	Down-regulation
CAMK_CAMK2_CAMK2D_ST	Q8WZ42	TTN	Q13557	CAMK2D	S15691	R15694L	15694	Missense	distal	3	no	49.674	41.439	EPSD	COSMIC	37.605	Down-regulation
CAMK_CAMK2_CAMK2D_ST	Q8WZ42	TTN	Q13557	CAMK2D	S15691	D15684G	15684	Missense	distal	-7	no	49.674	49.243	EPSD	COSMIC	37.605	Down-regulation
CAMK_CAMK2_CAMK2D_ST	Q8WZ42	TTN	Q13557	CAMK2D	S15691	R15696Q	15696	Missense	distal	5	no	49.674	51.694	EPSD	COSMIC;CCLE	37.605	Up-regulation
CAMK_CAMK2_CAMK2D_ST	Q8WZ42	TTN	Q13557	CAMK2D	S15691	K15687T	15687	Missense	distal	-4	no	49.674	50.676	EPSD	COSMIC	37.605	Up-regulation
CAMK_CAMK2_CAMK2D_ST	Q8WZ42	TTN	Q13557	CAMK2D	S15691	G15689A	15689	Missense	proximal	-2	no	49.674	49.501	EPSD	COSMIC	37.605	Down-regulation
CAMK_CAMK2_CAMK2D_ST	Q8WZ42	TTN	Q13557	CAMK2D	S15744	P15751S	15751	Missense	distal	7	no	49.029	48.061	EPSD	COSMIC	37.605	Down-regulation
CAMK_CAMK2_CAMK2D_ST	Q8WZ42	TTN	Q13557	CAMK2D	S15744	F15737I	15737	Missense	distal	-7	no	49.029	54.460	EPSD	COSMIC	37.605	Up-regulation
CAMK_CAMK2_CAMK2D_ST	Q8WZ42	TTN	Q13557	CAMK2D	S15744	E15750K	15750	Missense	distal	6	no	49.029	49.576	EPSD	COSMIC	37.605	Up-regulation
CAMK_CAMK2_CAMK2D_ST	Q8WZ42	TTN	Q13557	CAMK2D	T15989	E15995D	15995	Missense	distal	6	no	53.685	53.034	EPSD	COSMIC	37.605	Down-regulation
CAMK_CAMK2_CAMK2D_ST	Q8WZ42	TTN	Q13557	CAMK2D	T15989	E15992K	15992	Missense	distal	3	no	53.685	47.666	EPSD	COSMIC	37.605	Down-regulation
CAMK_CAMK2_CAMK2D_ST	Q8WZ42	TTN	Q13557	CAMK2D	T15989	T15989N	15989	Missense	central	0	yes	53.685	0.000	EPSD	COSMIC	37.605	Loss
CAMK_CAMK2_CAMK2D_ST	Q8WZ42	TTN	Q13557	CAMK2D	T15989	R15986Q	15986	Missense	distal	-3	no	53.685	42.462	EPSD	COSMIC	37.605	Down-regulation
CAMK_CAMK2_CAMK2D_ST	Q8WZ42	TTN	Q13557	CAMK2D	T16048	A16045S	16045	Missense	distal	-3	no	32.319	42.102	EPSD	COSMIC	37.605	Gain
CAMK_CAMK2_CAMK2D_ST	Q8WZ42	TTN	Q13557	CAMK2D	T16056	A16053V	16053	Missense	distal	-3	no	28.632	42.205	EPSD	COSMIC	37.605	Gain
CAMK_CAMK2_CAMK2D_ST	Q8WZ42	TTN	Q13557	CAMK2D	S16086	G16083R	16083	Missense	distal	-3	no	-4.111	38.847	EPSD	COSMIC	37.605	Gain
CAMK_CAMK2_CAMK2D_ST	Q8WZ42	TTN	Q13557	CAMK2D	S16236	D16241H	16241	Missense	distal	5	no	38.509	41.314	EPSD	COSMIC	37.605	Up-regulation
CAMK_CAMK2_CAMK2D_ST	Q8WZ42	TTN	Q13557	CAMK2D	S16236	L16240P	16240	Missense	distal	4	no	38.509	37.696	EPSD	COSMIC	37.605	Down-regulation
CAMK_CAMK2_CAMK2D_ST	Q8WZ42	TTN	Q13557	CAMK2D	S16236	D16241Y	16241	Missense	distal	5	no	38.509	40.336	EPSD	COSMIC	37.605	Up-regulation
CAMK_CAMK2_CAMK2D_ST	Q8WZ42	TTN	Q13557	CAMK2D	S16383	S16381Y	16381	Missense	proximal	-2	no	46.646	45.873	EPSD	COSMIC	37.605	Down-regulation
CAMK_CAMK2_CAMK2D_ST	Q8WZ42	TTN	Q13557	CAMK2D	S16383	S16390C	16390	Missense	distal	7	no	46.646	48.624	EPSD	COSMIC	37.605	Up-regulation
CAMK_CAMK2_CAMK2D_ST	Q8WZ42	TTN	Q13557	CAMK2D	S16383	S16383N	16383	Missense	central	0	yes	46.646	0.000	EPSD	COSMIC	37.605	Loss
CAMK_CAMK2_CAMK2D_ST	Q8WZ42	TTN	Q13557	CAMK2D	T16477	E16474K	16474	Missense	distal	-3	no	6.850	41.133	EPSD	COSMIC	37.605	Gain
CAMK_CAMK2_CAMK2D_ST	Q8WZ42	TTN	Q13557	CAMK2D	S16753	A16759T	16759	Missense	distal	6	no	38.087	34.494	EPSD	COSMIC	37.605	Loss
CAMK_CAMK2_CAMK2D_ST	Q8WZ42	TTN	Q13557	CAMK2D	S16753	A16751T	16751	Missense	proximal	-2	no	38.087	37.619	EPSD	COSMIC	37.605	Down-regulation
CAMK_CAMK2_CAMK2D_ST	Q8WZ42	TTN	Q13557	CAMK2D	S16753	C16749Y	16749	Missense	distal	-4	no	38.087	40.517	EPSD	COSMIC	37.605	Up-regulation
CAMK_CAMK2_CAMK2D_ST	Q8WZ42	TTN	Q13557	CAMK2D	S16753	Q16754H	16754	Missense	proximal	1	no	38.087	36.978	EPSD	COSMIC	37.605	Loss
CAMK_CAMK2_CAMK2D_ST	Q8WZ42	TTN	Q13557	CAMK2D	S16753	A16751V	16751	Missense	proximal	-2	no	38.087	38.360	EPSD	COSMIC	37.605	Up-regulation
CAMK_CAMK2_CAMK2D_ST	Q8WZ42	TTN	Q13557	CAMK2D	S16753	R16756Q	16756	Missense	distal	3	no	38.087	37.190	EPSD	COSMIC	37.605	Loss
CAMK_CAMK2_CAMK2D_ST	Q8WZ42	TTN	Q13557	CAMK2D	T17118	G17119C	17119	Missense	proximal	1	no	52.106	46.058	EPSD	COSMIC	37.605	Down-regulation
CAMK_CAMK2_CAMK2D_ST	Q8WZ42	TTN	Q13557	CAMK2D	T17118	T17124A	17124	Missense	distal	6	no	52.106	55.699	EPSD	COSMIC	37.605	Up-regulation
CAMK_CAMK2_CAMK2D_ST	Q8WZ42	TTN	Q13557	CAMK2D	T17190	E17185Q	17185	Missense	distal	-5	no	45.611	44.194	EPSD	COSMIC	37.605	Down-regulation
CAMK_CAMK2_CAMK2D_ST	Q8WZ42	TTN	Q13557	CAMK2D	T17190	H17193R	17193	Missense	distal	3	no	45.611	55.158	EPSD	COSMIC	37.605	Up-regulation
CAMK_CAMK2_CAMK2D_ST	Q8WZ42	TTN	Q13557	CAMK2D	T17190	E17197Q	17197	Missense	distal	7	no	45.611	44.463	EPSD	COSMIC	37.605	Down-regulation
CAMK_CAMK2_CAMK2D_ST	Q8WZ42	TTN	Q13557	CAMK2D	S17196	H17193R	17193	Missense	distal	-3	no	18.038	55.362	EPSD	COSMIC	37.605	Gain
CAMK_CAMK2_CAMK2D_ST	Q8WZ42	TTN	Q13557	CAMK2D	T17410	G17415R	17415	Missense	distal	5	no	44.647	44.115	EPSD	COSMIC	37.605	Down-regulation
CAMK_CAMK2_CAMK2D_ST	Q8WZ42	TTN	Q13557	CAMK2D	T17410	L17407F	17407	Missense	distal	-3	no	44.647	51.496	EPSD	COSMIC	37.605	Up-regulation
CAMK_CAMK2_CAMK2D_ST	Q8WZ42	TTN	Q13557	CAMK2D	T17591	W17590R	17590	Missense	proximal	-1	no	34.283	38.348	EPSD	COSMIC	37.605	Gain
CAMK_CAMK2_CAMK2D_ST	Q8WZ42	TTN	Q13557	CAMK2D	T17591	E17584K	17584	Missense	distal	-7	no	34.283	40.550	EPSD	COSMIC	37.605	Gain
CAMK_CAMK2_CAMK2D_ST	Q8WZ42	TTN	Q13557	CAMK2D	T17596	W17590R	17590	Missense	distal	-6	no	33.027	41.373	EPSD	COSMIC	37.605	Gain
CAMK_CAMK2_CAMK2D_ST	Q8WZ42	TTN	Q13557	CAMK2D	T17603	R17599Q	17599	Missense	distal	-4	no	47.419	44.422	EPSD	COSMIC	37.605	Down-regulation
CAMK_CAMK2_CAMK2D_ST	Q8WZ42	TTN	Q13557	CAMK2D	T17603	V17604I	17604	Missense	proximal	1	no	47.419	53.141	EPSD	COSMIC	37.605	Up-regulation
CAMK_CAMK2_CAMK2D_ST	Q8WZ42	TTN	Q13557	CAMK2D	T17797	T17800A	17800	Missense	distal	3	no	30.809	43.937	EPSD	COSMIC	37.605	Gain
CAMK_CAMK2_CAMK2D_ST	Q8WZ42	TTN	Q13557	CAMK2D	S17823	V17819I	17819	Missense	distal	-4	no	50.561	48.171	EPSD	COSMIC	37.605	Down-regulation
CAMK_CAMK2_CAMK2D_ST	Q8WZ42	TTN	Q13557	CAMK2D	S17823	S17826Y	17826	Missense	distal	3	no	50.561	54.007	EPSD	COSMIC	37.605	Up-regulation
CAMK_CAMK2_CAMK2D_ST	Q8WZ42	TTN	Q13557	CAMK2D	S17823	G17829D	17829	Missense	distal	6	no	50.561	48.238	EPSD	COSMIC	37.605	Down-regulation
CAMK_CAMK2_CAMK2D_ST	Q8WZ42	TTN	Q13557	CAMK2D	S17929	V17926L	17926	Missense	distal	-3	no	42.182	32.730	EPSD	COSMIC	37.605	Loss
CAMK_CAMK2_CAMK2D_ST	Q8WZ42	TTN	Q13557	CAMK2D	S17929	D17923N	17923	Missense	distal	-6	no	42.182	55.344	EPSD	COSMIC	37.605	Up-regulation
CAMK_CAMK2_CAMK2D_ST	Q8WZ42	TTN	Q13557	CAMK2D	S17929	P17924T	17924	Missense	distal	-5	no	42.182	42.051	EPSD	COSMIC	37.605	Down-regulation
CAMK_CAMK2_CAMK2D_ST	Q8WZ42	TTN	Q13557	CAMK2D	S17929	V17926E	17926	Missense	distal	-3	no	42.182	8.875	EPSD	COSMIC	37.605	Loss
CAMK_CAMK2_CAMK2D_ST	Q8WZ42	TTN	Q13557	CAMK2D	T17979	E17978G	17978	Missense	proximal	-1	no	44.039	43.893	EPSD	COSMIC	37.605	Down-regulation
CAMK_CAMK2_CAMK2D_ST	Q8WZ42	TTN	Q13557	CAMK2D	T17979	S17981C	17981	Missense	proximal	2	no	44.039	39.850	EPSD	COSMIC	37.605	Down-regulation
CAMK_CAMK2_CAMK2D_ST	Q8WZ42	TTN	Q13557	CAMK2D	T17979	E17978K	17978	Missense	proximal	-1	no	44.039	44.434	EPSD	COSMIC	37.605	Up-regulation
CAMK_CAMK2_CAMK2D_ST	Q8WZ42	TTN	Q13557	CAMK2D	T17979	S17981T	17981	Missense	proximal	2	no	44.039	40.768	EPSD	COSMIC	37.605	Down-regulation
CAMK_CAMK2_CAMK2D_ST	Q8WZ42	TTN	Q13557	CAMK2D	T17979	R17983Q	17983	Missense	distal	4	no	44.039	44.651	EPSD	COSMIC	37.605	Up-regulation
CAMK_CAMK2_CAMK2D_ST	Q8WZ42	TTN	Q13557	CAMK2D	T17979	S17981Y	17981	Missense	proximal	2	no	44.039	36.999	EPSD	COSMIC	37.605	Loss
CAMK_CAMK2_CAMK2D_ST	Q8WZ42	TTN	Q13557	CAMK2D	T17988	D17990N	17990	Missense	proximal	2	no	51.440	40.015	EPSD	COSMIC	37.605	Down-regulation
CAMK_CAMK2_CAMK2D_ST	Q8WZ42	TTN	Q13557	CAMK2D	T17988	P17991T	17991	Missense	distal	3	no	51.440	46.048	EPSD	COSMIC	37.605	Down-regulation
CAMK_CAMK2_CAMK2D_ST	Q8WZ42	TTN	Q13557	CAMK2D	T17988	S17981C	17981	Missense	distal	-7	no	51.440	55.218	EPSD	COSMIC	37.605	Up-regulation
CAMK_CAMK2_CAMK2D_ST	Q8WZ42	TTN	Q13557	CAMK2D	T17988	S17981T	17981	Missense	distal	-7	no	51.440	50.640	EPSD	COSMIC	37.605	Down-regulation
CAMK_CAMK2_CAMK2D_ST	Q8WZ42	TTN	Q13557	CAMK2D	T17988	R17983Q	17983	Missense	distal	-5	no	51.440	51.224	EPSD	COSMIC	37.605	Down-regulation
CAMK_CAMK2_CAMK2D_ST	Q8WZ42	TTN	Q13557	CAMK2D	T17988	S17981Y	17981	Missense	distal	-7	no	51.440	52.306	EPSD	COSMIC	37.605	Up-regulation
CAMK_CAMK2_CAMK2D_ST	Q8WZ42	TTN	Q13557	CAMK2D	T18104	D18108G	18108	Missense	distal	4	no	41.420	42.739	EPSD	COSMIC	37.605	Up-regulation
CAMK_CAMK2_CAMK2D_ST	Q8WZ42	TTN	Q13557	CAMK2D	T18104	G18109S	18109	Missense	distal	5	no	41.420	40.469	EPSD	COSMIC	37.605	Down-regulation
CAMK_CAMK2_CAMK2D_ST	Q8WZ42	TTN	Q13557	CAMK2D	T18505	R18503H	18503	Missense	proximal	-2	no	50.752	49.860	EPSD	COSMIC	37.605	Down-regulation
CAMK_CAMK2_CAMK2D_ST	Q8WZ42	TTN	Q13557	CAMK2D	T18505	C18500R	18500	Missense	distal	-5	no	50.752	50.452	EPSD	COSMIC	37.605	Down-regulation
CAMK_CAMK2_CAMK2D_ST	Q8WZ42	TTN	Q13557	CAMK2D	T18577	T18577N	18577	Missense	central	0	yes	52.395	0.000	EPSD	COSMIC	37.605	Loss
CAMK_CAMK2_CAMK2D_ST	Q8WZ42	TTN	Q13557	CAMK2D	T18577	R18574T	18574	Missense	distal	-3	no	52.395	30.764	EPSD	COSMIC	37.605	Loss
CAMK_CAMK2_CAMK2D_ST	Q8WZ42	TTN	Q13557	CAMK2D	T18577	T18573A	18573	Missense	distal	-4	no	52.395	51.980	EPSD	COSMIC	37.605	Down-regulation
CAMK_CAMK2_CAMK2D_ST	Q8WZ42	TTN	Q13557	CAMK2D	T18577	Q18571K	18571	Missense	distal	-6	no	52.395	47.122	EPSD	COSMIC	37.605	Down-regulation
CAMK_CAMK2_CAMK2D_ST	Q8WZ42	TTN	Q13557	CAMK2D	T18577	G18584D	18584	Missense	distal	7	no	52.395	53.386	EPSD	COSMIC	37.605	Up-regulation
CAMK_CAMK2_CAMK2D_ST	Q8WZ42	TTN	Q13557	CAMK2D	S18583	T18577N	18577	Missense	distal	-6	no	51.346	63.970	EPSD	COSMIC	37.605	Up-regulation
CAMK_CAMK2_CAMK2D_ST	Q8WZ42	TTN	Q13557	CAMK2D	S18583	K18589N	18589	Missense	distal	6	no	51.346	52.244	EPSD	COSMIC	37.605	Up-regulation
CAMK_CAMK2_CAMK2D_ST	Q8WZ42	TTN	Q13557	CAMK2D	S18583	G18584D	18584	Missense	proximal	1	no	51.346	46.421	EPSD	COSMIC	37.605	Down-regulation
CAMK_CAMK2_CAMK2D_ST	Q8WZ42	TTN	Q13557	CAMK2D	T18682	V18677M	18677	Missense	distal	-5	no	54.214	53.515	EPSD	COSMIC	37.605	Down-regulation
CAMK_CAMK2_CAMK2D_ST	Q8WZ42	TTN	Q13557	CAMK2D	T18682	R18678Q	18678	Missense	distal	-4	no	54.214	51.218	EPSD	COSMIC	37.605	Down-regulation
CAMK_CAMK2_CAMK2D_ST	Q8WZ42	TTN	Q13557	CAMK2D	T18682	D18686G	18686	Missense	distal	4	no	54.214	55.534	EPSD	COSMIC	37.605	Up-regulation
CAMK_CAMK2_CAMK2D_ST	Q8WZ42	TTN	Q13557	CAMK2D	T18852	R18858L	18858	Missense	distal	6	no	43.296	41.815	EPSD	COSMIC	37.605	Down-regulation
CAMK_CAMK2_CAMK2D_ST	Q8WZ42	TTN	Q13557	CAMK2D	T18852	I18855T	18855	Missense	distal	3	no	43.296	46.169	EPSD	COSMIC	37.605	Up-regulation
CAMK_CAMK2_CAMK2D_ST	Q8WZ42	TTN	Q13557	CAMK2D	T18852	G18850R	18850	Missense	proximal	-2	no	43.296	44.014	EPSD	COSMIC	37.605	Up-regulation
CAMK_CAMK2_CAMK2D_ST	Q8WZ42	TTN	Q13557	CAMK2D	T18852	T18852P	18852	Missense	central	0	yes	43.296	0.000	EPSD	COSMIC	37.605	Loss
CAMK_CAMK2_CAMK2D_ST	Q8WZ42	TTN	Q13557	CAMK2D	T18852	L18856M	18856	Missense	distal	4	no	43.296	42.095	EPSD	COSMIC	37.605	Down-regulation
CAMK_CAMK2_CAMK2D_ST	Q8WZ42	TTN	Q13557	CAMK2D	S18976	K18969N	18969	Missense	distal	-7	no	55.000	48.213	EPSD	COSMIC	37.605	Down-regulation
CAMK_CAMK2_CAMK2D_ST	Q8WZ42	TTN	Q13557	CAMK2D	S18976	N18971S	18971	Missense	distal	-5	no	55.000	54.246	EPSD	COSMIC	37.605	Down-regulation
CAMK_CAMK2_CAMK2D_ST	Q8WZ42	TTN	Q13557	CAMK2D	S18976	I18977V	18977	Missense	proximal	1	no	55.000	49.277	EPSD	COSMIC	37.605	Down-regulation
CAMK_CAMK2_CAMK2D_ST	Q8WZ42	TTN	Q13557	CAMK2D	S18976	Q18972K	18972	Missense	distal	-4	no	55.000	56.773	EPSD	COSMIC	37.605	Up-regulation
CAMK_CAMK2_CAMK2D_ST	Q8WZ42	TTN	Q13557	CAMK2D	T19042	K19039R	19039	Missense	distal	-3	no	34.105	45.512	EPSD	COSMIC	37.605	Gain
CAMK_CAMK2_CAMK2D_ST	Q8WZ42	TTN	Q13557	CAMK2D	T19172	K19166N	19166	Missense	distal	-6	no	29.126	38.092	EPSD	COSMIC;CCLE	37.605	Gain
CAMK_CAMK2_CAMK2D_ST	Q8WZ42	TTN	Q13557	CAMK2D	T19283	P19280S	19280	Missense	distal	-3	no	-15.113	38.143	EPSD	COSMIC	37.605	Gain
CAMK_CAMK2_CAMK2D_ST	Q8WZ42	TTN	Q13557	CAMK2D	T19305	P19308A	19308	Missense	distal	3	no	30.348	38.083	EPSD	COSMIC	37.605	Gain
CAMK_CAMK2_CAMK2D_ST	Q8WZ42	TTN	Q13557	CAMK2D	S19809	L19810F	19810	Missense	proximal	1	no	33.066	41.621	EPSD	COSMIC	37.605	Gain
CAMK_CAMK2_CAMK2D_ST	Q8WZ42	TTN	Q13557	CAMK2D	S19893	K19891N	19891	Missense	proximal	-2	no	45.314	45.790	EPSD	COSMIC	37.605	Up-regulation
CAMK_CAMK2_CAMK2D_ST	Q8WZ42	TTN	Q13557	CAMK2D	S19893	R19890W	19890	Missense	distal	-3	no	45.314	4.278	EPSD	COSMIC	37.605	Loss
CAMK_CAMK2_CAMK2D_ST	Q8WZ42	TTN	Q13557	CAMK2D	S19893	D19887G	19887	Missense	distal	-6	no	45.314	50.104	EPSD	COSMIC	37.605	Up-regulation
CAMK_CAMK2_CAMK2D_ST	Q8WZ42	TTN	Q13557	CAMK2D	S19893	Y19895F	19895	Missense	proximal	2	no	45.314	46.159	EPSD	COSMIC	37.605	Up-regulation
CAMK_CAMK2_CAMK2D_ST	Q8WZ42	TTN	Q13557	CAMK2D	S19893	V19888G	19888	Missense	distal	-5	no	45.314	45.409	EPSD	COSMIC	37.605	Up-regulation
CAMK_CAMK2_CAMK2D_ST	Q8WZ42	TTN	Q13557	CAMK2D	S20101	K20098R	20098	Missense	distal	-3	no	35.620	47.027	EPSD	COSMIC	37.605	Gain
CAMK_CAMK2_CAMK2D_ST	Q8WZ42	TTN	Q13557	CAMK2D	T20168	V20164L	20164	Missense	distal	-4	no	50.073	46.009	EPSD	COSMIC	37.605	Down-regulation
CAMK_CAMK2_CAMK2D_ST	Q8WZ42	TTN	Q13557	CAMK2D	T20168	V20164I	20164	Missense	distal	-4	no	50.073	47.683	EPSD	COSMIC	37.605	Down-regulation
CAMK_CAMK2_CAMK2D_ST	Q8WZ42	TTN	Q13557	CAMK2D	T20168	A20169V	20169	Missense	proximal	1	no	50.073	56.505	EPSD	COSMIC	37.605	Up-regulation
CAMK_CAMK2_CAMK2D_ST	Q8WZ42	TTN	Q13557	CAMK2D	T20168	R20165Q	20165	Missense	distal	-3	no	50.073	38.851	EPSD	COSMIC	37.605	Down-regulation
CAMK_CAMK2_CAMK2D_ST	Q8WZ42	TTN	Q13557	CAMK2D	T20168	W20163R	20163	Missense	distal	-5	no	50.073	48.137	EPSD	COSMIC;CCLE	37.605	Down-regulation
CAMK_CAMK2_CAMK2D_ST	Q8WZ42	TTN	Q13557	CAMK2D	T20168	Q20175K	20175	Missense	distal	7	no	50.073	51.299	EPSD	COSMIC	37.605	Up-regulation
CAMK_CAMK2_CAMK2D_ST	Q8WZ42	TTN	Q13557	CAMK2D	T20168	A20169E	20169	Missense	proximal	1	no	50.073	54.904	EPSD	COSMIC	37.605	Up-regulation
CAMK_CAMK2_CAMK2D_ST	Q8WZ42	TTN	Q13557	CAMK2D	S20205	P20210Q	20210	Missense	distal	5	no	37.917	37.503	EPSD	COSMIC	37.605	Loss
CAMK_CAMK2_CAMK2D_ST	Q8WZ42	TTN	Q13557	CAMK2D	T20261	V20254L	20254	Missense	distal	-7	no	33.376	39.368	EPSD	COSMIC	37.605	Gain
CAMK_CAMK2_CAMK2D_ST	Q8WZ42	TTN	Q13557	CAMK2D	T20307	S20301G	20301	Missense	distal	-6	no	43.366	44.646	EPSD	COSMIC	37.605	Up-regulation
CAMK_CAMK2_CAMK2D_ST	Q8WZ42	TTN	Q13557	CAMK2D	T20307	T20307A	20307	Missense	central	0	yes	43.366	0.000	EPSD	COSMIC	37.605	Loss
CAMK_CAMK2_CAMK2D_ST	Q8WZ42	TTN	Q13557	CAMK2D	T20307	D20314G	20314	Missense	distal	7	no	43.366	42.374	EPSD	COSMIC	37.605	Down-regulation
CAMK_CAMK2_CAMK2D_ST	Q8WZ42	TTN	Q13557	CAMK2D	T20477	G20482R	20482	Missense	distal	5	no	49.398	48.867	EPSD	COSMIC	37.605	Down-regulation
CAMK_CAMK2_CAMK2D_ST	Q8WZ42	TTN	Q13557	CAMK2D	T20477	G20478C	20478	Missense	proximal	1	no	49.398	43.350	EPSD	COSMIC	37.605	Down-regulation
CAMK_CAMK2_CAMK2D_ST	Q8WZ42	TTN	Q13557	CAMK2D	T20721	I20725V	20725	Missense	distal	4	no	51.310	49.116	EPSD	COSMIC	37.605	Down-regulation
CAMK_CAMK2_CAMK2D_ST	Q8WZ42	TTN	Q13557	CAMK2D	T20721	P20717Q	20717	Missense	distal	-4	no	51.310	49.999	EPSD	COSMIC	37.605	Down-regulation
CAMK_CAMK2_CAMK2D_ST	Q8WZ42	TTN	Q13557	CAMK2D	T20721	D20728Y	20728	Missense	distal	7	no	51.310	51.682	EPSD	COSMIC	37.605	Up-regulation
CAMK_CAMK2_CAMK2D_ST	Q8WZ42	TTN	Q13557	CAMK2D	T20721	P20717H	20717	Missense	distal	-4	no	51.310	52.062	EPSD	COSMIC	37.605	Up-regulation
CAMK_CAMK2_CAMK2D_ST	Q8WZ42	TTN	Q13557	CAMK2D	T20721	T20721I	20721	Missense	central	0	yes	51.310	0.000	EPSD	COSMIC	37.605	Loss
CAMK_CAMK2_CAMK2D_ST	Q8WZ42	TTN	Q13557	CAMK2D	S20759	E20756Q	20756	Missense	distal	-3	no	9.253	43.721	EPSD	COSMIC	37.605	Gain
CAMK_CAMK2_CAMK2D_ST	Q8WZ42	TTN	Q13557	CAMK2D	S20864	S20864N	20864	Missense	central	0	yes	43.845	0.000	EPSD	COSMIC	37.605	Loss
CAMK_CAMK2_CAMK2D_ST	Q8WZ42	TTN	Q13557	CAMK2D	S20864	L20865P	20865	Missense	proximal	1	no	43.845	40.306	EPSD	COSMIC	37.605	Down-regulation
CAMK_CAMK2_CAMK2D_ST	Q8WZ42	TTN	Q13557	CAMK2D	T20994	I20995V	20995	Missense	proximal	1	no	47.634	41.911	EPSD	COSMIC	37.605	Down-regulation
CAMK_CAMK2_CAMK2D_ST	Q8WZ42	TTN	Q13557	CAMK2D	T20994	G20989A	20989	Missense	distal	-5	no	47.634	48.371	EPSD	COSMIC	37.605	Up-regulation
CAMK_CAMK2_CAMK2D_ST	Q8WZ42	TTN	Q13557	CAMK2D	T20994	V20999A	20999	Missense	distal	5	no	47.634	47.846	EPSD	COSMIC	37.605	Up-regulation
CAMK_CAMK2_CAMK2D_ST	Q8WZ42	TTN	Q13557	CAMK2D	T20994	G20993E	20993	Missense	proximal	-1	no	47.634	47.780	EPSD	COSMIC	37.605	Up-regulation
CAMK_CAMK2_CAMK2D_ST	Q8WZ42	TTN	Q13557	CAMK2D	T20994	I20997V	20997	Missense	distal	3	no	47.634	42.402	EPSD	COSMIC	37.605	Down-regulation
CAMK_CAMK2_CAMK2D_ST	Q8WZ42	TTN	Q13557	CAMK2D	T20994	S20996T	20996	Missense	proximal	2	no	47.634	44.362	EPSD	COSMIC	37.605	Down-regulation
CAMK_CAMK2_CAMK2D_ST	Q8WZ42	TTN	Q13557	CAMK2D	T20994	E20992K	20992	Missense	proximal	-2	no	47.634	47.872	EPSD	COSMIC	37.605	Up-regulation
CAMK_CAMK2_CAMK2D_ST	Q8WZ42	TTN	Q13557	CAMK2D	T20994	G20993D	20993	Missense	proximal	-1	no	47.634	45.423	EPSD	COSMIC	37.605	Down-regulation
CAMK_CAMK2_CAMK2D_ST	Q8WZ42	TTN	Q13557	CAMK2D	S21055	T21052K	21052	Missense	distal	-3	no	37.318	47.541	EPSD	COSMIC	37.605	Gain
CAMK_CAMK2_CAMK2D_ST	Q8WZ42	TTN	Q13557	CAMK2D	S21338	P21336S	21336	Missense	proximal	-2	no	49.062	48.964	EPSD	COSMIC	37.605	Down-regulation
CAMK_CAMK2_CAMK2D_ST	Q8WZ42	TTN	Q13557	CAMK2D	S21338	P21336T	21336	Missense	proximal	-2	no	49.062	48.139	EPSD	COSMIC	37.605	Down-regulation
CAMK_CAMK2_CAMK2D_ST	Q8WZ42	TTN	Q13557	CAMK2D	S21338	G21344R	21344	Missense	distal	6	no	49.062	48.590	EPSD	COSMIC	37.605	Down-regulation
CAMK_CAMK2_CAMK2D_ST	Q8WZ42	TTN	Q13557	CAMK2D	S21338	L21331F	21331	Missense	distal	-7	no	49.062	43.058	EPSD	COSMIC	37.605	Down-regulation
CAMK_CAMK2_CAMK2D_ST	Q8WZ42	TTN	Q13557	CAMK2D	S21338	G21332R	21332	Missense	distal	-6	no	49.062	50.879	EPSD	COSMIC;CCLE	37.605	Up-regulation
CAMK_CAMK2_CAMK2D_ST	Q8WZ42	TTN	Q13557	CAMK2D	T21378	G21375S	21375	Missense	distal	-3	no	18.561	45.345	EPSD	COSMIC	37.605	Gain
CAMK_CAMK2_CAMK2D_ST	Q8WZ42	TTN	Q13557	CAMK2D	T21651	I21657S	21657	Missense	distal	6	no	37.852	38.407	EPSD	COSMIC	37.605	Up-regulation
CAMK_CAMK2_CAMK2D_ST	Q8WZ42	TTN	Q13557	CAMK2D	T21651	L21655F	21655	Missense	distal	4	no	37.852	35.761	EPSD	COSMIC	37.605	Loss
CAMK_CAMK2_CAMK2D_ST	Q8WZ42	TTN	Q13557	CAMK2D	T21651	T21650A	21650	Missense	proximal	-1	no	37.852	36.197	EPSD	COSMIC	37.605	Loss
CAMK_CAMK2_CAMK2D_ST	Q8WZ42	TTN	Q13557	CAMK2D	T21651	T21653I	21653	Missense	proximal	2	no	37.852	41.944	EPSD	COSMIC	37.605	Up-regulation
CAMK_CAMK2_CAMK2D_ST	Q8WZ42	TTN	Q13557	CAMK2D	S21755	S21755F	21755	Missense	central	0	yes	38.251	0.000	EPSD	COSMIC	37.605	Loss
CAMK_CAMK2_CAMK2D_ST	Q8WZ42	TTN	Q13557	CAMK2D	S21755	E21754K	21754	Missense	proximal	-1	no	38.251	38.646	EPSD	COSMIC	37.605	Up-regulation
CAMK_CAMK2_CAMK2D_ST	Q8WZ42	TTN	Q13557	CAMK2D	S21755	A21748T	21748	Missense	distal	-7	no	38.251	38.138	EPSD	COSMIC	37.605	Down-regulation
CAMK_CAMK2_CAMK2D_ST	Q8WZ42	TTN	Q13557	CAMK2D	S21755	L21758V	21758	Missense	distal	3	no	38.251	33.373	EPSD	COSMIC	37.605	Loss
CAMK_CAMK2_CAMK2D_ST	Q8WZ42	TTN	Q13557	CAMK2D	T21794	L21801Q	21801	Missense	distal	7	no	46.526	45.062	EPSD	COSMIC	37.605	Down-regulation
CAMK_CAMK2_CAMK2D_ST	Q8WZ42	TTN	Q13557	CAMK2D	T21794	G21796C	21796	Missense	proximal	2	no	46.526	40.256	EPSD	COSMIC	37.605	Down-regulation
CAMK_CAMK2_CAMK2D_ST	Q8WZ42	TTN	Q13557	CAMK2D	T21794	P21797S	21797	Missense	distal	3	no	46.526	47.798	EPSD	COSMIC	37.605	Up-regulation
CAMK_CAMK2_CAMK2D_ST	Q8WZ42	TTN	Q13557	CAMK2D	T21794	P21797Q	21797	Missense	distal	3	no	46.526	45.245	EPSD	COSMIC	37.605	Down-regulation
CAMK_CAMK2_CAMK2D_ST	Q8WZ42	TTN	Q13557	CAMK2D	T21837	I21830M	21830	Missense	distal	-7	no	43.273	42.919	EPSD	COSMIC	37.605	Down-regulation
CAMK_CAMK2_CAMK2D_ST	Q8WZ42	TTN	Q13557	CAMK2D	T21837	R21838P	21838	Missense	proximal	1	no	43.273	33.413	EPSD	COSMIC	37.605	Loss
CAMK_CAMK2_CAMK2D_ST	Q8WZ42	TTN	Q13557	CAMK2D	T21837	S21840C	21840	Missense	distal	3	no	43.273	44.309	EPSD	COSMIC	37.605	Up-regulation
CAMK_CAMK2_CAMK2D_ST	Q8WZ42	TTN	Q13557	CAMK2D	T21837	S21842A	21842	Missense	distal	5	no	43.273	45.442	EPSD	COSMIC	37.605	Up-regulation
CAMK_CAMK2_CAMK2D_ST	Q8WZ42	TTN	Q13557	CAMK2D	T21837	A21844T	21844	Missense	distal	7	no	43.273	44.070	EPSD	COSMIC	37.605	Up-regulation
CAMK_CAMK2_CAMK2D_ST	Q8WZ42	TTN	Q13557	CAMK2D	S21840	K21847E	21847	Missense	distal	7	no	42.901	42.822	EPSD	COSMIC	37.605	Down-regulation
CAMK_CAMK2_CAMK2D_ST	Q8WZ42	TTN	Q13557	CAMK2D	S21840	T21845I	21845	Missense	distal	5	no	42.901	42.506	EPSD	COSMIC	37.605	Down-regulation
CAMK_CAMK2_CAMK2D_ST	Q8WZ42	TTN	Q13557	CAMK2D	S21840	R21838P	21838	Missense	proximal	-2	no	42.901	42.466	EPSD	COSMIC	37.605	Down-regulation
CAMK_CAMK2_CAMK2D_ST	Q8WZ42	TTN	Q13557	CAMK2D	S21840	S21840C	21840	Missense	central	0	yes	42.901	0.000	EPSD	COSMIC	37.605	Loss
CAMK_CAMK2_CAMK2D_ST	Q8WZ42	TTN	Q13557	CAMK2D	S21840	S21842A	21842	Missense	proximal	2	no	42.901	44.281	EPSD	COSMIC	37.605	Up-regulation
CAMK_CAMK2_CAMK2D_ST	Q8WZ42	TTN	Q13557	CAMK2D	S21840	A21844T	21844	Missense	distal	4	no	42.901	43.445	EPSD	COSMIC	37.605	Up-regulation
CAMK_CAMK2_CAMK2D_ST	Q8WZ42	TTN	Q13557	CAMK2D	T21924	D21918N	21918	Missense	distal	-6	no	25.351	38.514	EPSD	COSMIC	37.605	Gain
CAMK_CAMK2_CAMK2D_ST	Q8WZ42	TTN	Q13557	CAMK2D	T22152	R22149S	22149	Missense	distal	-3	no	55.095	38.922	EPSD	COSMIC	37.605	Down-regulation
CAMK_CAMK2_CAMK2D_ST	Q8WZ42	TTN	Q13557	CAMK2D	T22152	E22155Q	22155	Missense	distal	3	no	55.095	49.496	EPSD	COSMIC	37.605	Down-regulation
CAMK_CAMK2_CAMK2D_ST	Q8WZ42	TTN	Q13557	CAMK2D	T22152	A22147V	22147	Missense	distal	-5	no	55.095	54.263	EPSD	COSMIC	37.605	Down-regulation
CAMK_CAMK2_CAMK2D_ST	Q8WZ42	TTN	Q13557	CAMK2D	S22456	R22454K	22454	Missense	proximal	-2	no	50.123	49.374	EPSD	COSMIC	37.605	Down-regulation
CAMK_CAMK2_CAMK2D_ST	Q8WZ42	TTN	Q13557	CAMK2D	S22456	G22457C	22457	Missense	proximal	1	no	50.123	44.075	EPSD	COSMIC	37.605	Down-regulation
CAMK_CAMK2_CAMK2D_ST	Q8WZ42	TTN	Q13557	CAMK2D	S22456	S22456L	22456	Missense	central	0	yes	50.123	0.000	EPSD	COSMIC	37.605	Loss
CAMK_CAMK2_CAMK2D_ST	Q8WZ42	TTN	Q13557	CAMK2D	S22525	R22526T	22526	Missense	proximal	1	no	55.680	47.052	EPSD	COSMIC	37.605	Down-regulation
CAMK_CAMK2_CAMK2D_ST	Q8WZ42	TTN	Q13557	CAMK2D	S22534	A22533T	22533	Missense	proximal	-1	no	36.167	37.822	EPSD	COSMIC	37.605	Gain
CAMK_CAMK2_CAMK2D_ST	Q8WZ42	TTN	Q13557	CAMK2D	S22534	E22535V	22535	Missense	proximal	1	no	36.167	37.767	EPSD	COSMIC	37.605	Gain
CAMK_CAMK2_CAMK2D_ST	Q8WZ42	TTN	Q13557	CAMK2D	S22853	I22857T	22857	Missense	distal	4	no	38.703	37.695	EPSD	COSMIC	37.605	Down-regulation
CAMK_CAMK2_CAMK2D_ST	Q8WZ42	TTN	Q13557	CAMK2D	S22853	N22847S	22847	Missense	distal	-6	no	38.703	29.050	EPSD	COSMIC	37.605	Loss
CAMK_CAMK2_CAMK2D_ST	Q8WZ42	TTN	Q13557	CAMK2D	S22853	D22852G	22852	Missense	proximal	-1	no	38.703	40.914	EPSD	COSMIC	37.605	Up-regulation
CAMK_CAMK2_CAMK2D_ST	Q8WZ42	TTN	Q13557	CAMK2D	S22853	L22858F	22858	Missense	distal	5	no	38.703	37.734	EPSD	COSMIC	37.605	Down-regulation
CAMK_CAMK2_CAMK2D_ST	Q8WZ42	TTN	Q13557	CAMK2D	S22853	G22846E	22846	Missense	distal	-7	no	38.703	39.451	EPSD	COSMIC	37.605	Up-regulation
CAMK_CAMK2_CAMK2D_ST	Q8WZ42	TTN	Q13557	CAMK2D	S22853	F22851L	22851	Missense	proximal	-2	no	38.703	38.570	EPSD	COSMIC;CCLE	37.605	Down-regulation
CAMK_CAMK2_CAMK2D_ST	Q8WZ42	TTN	Q13557	CAMK2D	T22878	V22873A	22873	Missense	distal	-5	no	52.521	53.353	EPSD	COSMIC	37.605	Up-regulation
CAMK_CAMK2_CAMK2D_ST	Q8WZ42	TTN	Q13557	CAMK2D	S22926	S22920T	22920	Missense	distal	-6	no	39.403	36.431	EPSD	COSMIC	37.605	Loss
CAMK_CAMK2_CAMK2D_ST	Q8WZ42	TTN	Q13557	CAMK2D	S22969	P22976S	22976	Missense	distal	7	no	40.024	39.057	EPSD	COSMIC	37.605	Down-regulation
CAMK_CAMK2_CAMK2D_ST	Q8WZ42	TTN	Q13557	CAMK2D	S23063	P23065T	23065	Missense	proximal	2	no	38.882	38.032	EPSD	COSMIC	37.605	Down-regulation
CAMK_CAMK2_CAMK2D_ST	Q8WZ42	TTN	Q13557	CAMK2D	S23063	V23066M	23066	Missense	distal	3	no	38.882	46.506	EPSD	COSMIC	37.605	Up-regulation
CAMK_CAMK2_CAMK2D_ST	Q8WZ42	TTN	Q13557	CAMK2D	S23063	P23065S	23065	Missense	proximal	2	no	38.882	41.303	EPSD	COSMIC	37.605	Up-regulation
CAMK_CAMK2_CAMK2D_ST	Q8WZ42	TTN	Q13557	CAMK2D	T23085	G23089M	23089	Missense	distal	4	no	38.198	38.131	EPSD	COSMIC	37.605	Down-regulation
CAMK_CAMK2_CAMK2D_ST	Q8WZ42	TTN	Q13557	CAMK2D	T23085	A23088S	23088	Missense	distal	3	no	38.198	31.735	EPSD	COSMIC	37.605	Loss
CAMK_CAMK2_CAMK2D_ST	Q8WZ42	TTN	Q13557	CAMK2D	T23085	A23088T	23088	Missense	distal	3	no	38.198	25.070	EPSD	COSMIC	37.605	Loss
CAMK_CAMK2_CAMK2D_ST	Q8WZ42	TTN	Q13557	CAMK2D	T23085	A23088V	23088	Missense	distal	3	no	38.198	16.965	EPSD	COSMIC	37.605	Loss
CAMK_CAMK2_CAMK2D_ST	Q8WZ42	TTN	Q13557	CAMK2D	T23085	E23090K	23090	Missense	distal	5	no	38.198	38.649	EPSD	COSMIC	37.605	Up-regulation
CAMK_CAMK2_CAMK2D_ST	Q8WZ42	TTN	Q13557	CAMK2D	T23085	L23079F	23079	Missense	distal	-6	no	38.198	44.959	EPSD	COSMIC;CCLE	37.605	Up-regulation
CAMK_CAMK2_CAMK2D_ST	Q8WZ42	TTN	Q13557	CAMK2D	T23214	T23210A	23210	Missense	distal	-4	no	46.872	46.456	EPSD	COSMIC	37.605	Down-regulation
CAMK_CAMK2_CAMK2D_ST	Q8WZ42	TTN	Q13557	CAMK2D	T23214	W23215C	23215	Missense	proximal	1	no	46.872	41.586	EPSD	COSMIC	37.605	Down-regulation
CAMK_CAMK2_CAMK2D_ST	Q8WZ42	TTN	Q13557	CAMK2D	T23221	A23223T	23223	Missense	proximal	2	no	40.243	35.592	EPSD	COSMIC	37.605	Loss
CAMK_CAMK2_CAMK2D_ST	Q8WZ42	TTN	Q13557	CAMK2D	T23221	I23227V	23227	Missense	distal	6	no	40.243	41.991	EPSD	COSMIC	37.605	Up-regulation
CAMK_CAMK2_CAMK2D_ST	Q8WZ42	TTN	Q13557	CAMK2D	T23221	R23224K	23224	Missense	distal	3	no	40.243	38.927	EPSD	COSMIC	37.605	Down-regulation
CAMK_CAMK2_CAMK2D_ST	Q8WZ42	TTN	Q13557	CAMK2D	T23221	W23215C	23215	Missense	distal	-6	no	40.243	45.719	EPSD	COSMIC	37.605	Up-regulation
CAMK_CAMK2_CAMK2D_ST	Q8WZ42	TTN	Q13557	CAMK2D	T23221	A23223V	23223	Missense	proximal	2	no	40.243	34.368	EPSD	COSMIC	37.605	Loss
CAMK_CAMK2_CAMK2D_ST	Q8WZ42	TTN	Q13557	CAMK2D	T23226	A23223V	23223	Missense	distal	-3	no	31.178	44.750	EPSD	COSMIC	37.605	Gain
CAMK_CAMK2_CAMK2D_ST	Q8WZ42	TTN	Q13557	CAMK2D	T23234	I23227V	23227	Missense	distal	-7	no	48.833	43.415	EPSD	COSMIC	37.605	Down-regulation
CAMK_CAMK2_CAMK2D_ST	Q8WZ42	TTN	Q13557	CAMK2D	T23234	E23237K	23237	Missense	distal	3	no	48.833	42.814	EPSD	COSMIC	37.605	Down-regulation
CAMK_CAMK2_CAMK2D_ST	Q8WZ42	TTN	Q13557	CAMK2D	T23234	A23229V	23229	Missense	distal	-5	no	48.833	48.001	EPSD	COSMIC	37.605	Down-regulation
CAMK_CAMK2_CAMK2D_ST	Q8WZ42	TTN	Q13557	CAMK2D	T23234	K23233E	23233	Missense	proximal	-1	no	48.833	48.439	EPSD	COSMIC	37.605	Down-regulation
CAMK_CAMK2_CAMK2D_ST	Q8WZ42	TTN	Q13557	CAMK2D	T23555	E23551Q	23551	Missense	distal	-4	no	42.732	44.213	EPSD	COSMIC	37.605	Up-regulation
CAMK_CAMK2_CAMK2D_ST	Q8WZ42	TTN	Q13557	CAMK2D	T23555	S23553F	23553	Missense	proximal	-2	no	42.732	42.490	EPSD	COSMIC	37.605	Down-regulation
CAMK_CAMK2_CAMK2D_ST	Q8WZ42	TTN	Q13557	CAMK2D	T23555	T23555A	23555	Missense	central	0	yes	42.732	0.000	EPSD	COSMIC	37.605	Loss
CAMK_CAMK2_CAMK2D_ST	Q8WZ42	TTN	Q13557	CAMK2D	T23555	R23552I	23552	Missense	distal	-3	no	42.732	29.629	EPSD	COSMIC	37.605	Loss
CAMK_CAMK2_CAMK2D_ST	Q8WZ42	TTN	Q13557	CAMK2D	T23555	D23562E	23562	Missense	distal	7	no	42.732	42.383	EPSD	COSMIC	37.605	Down-regulation
CAMK_CAMK2_CAMK2D_ST	Q8WZ42	TTN	Q13557	CAMK2D	T23555	K23559N	23559	Missense	distal	4	no	42.732	42.317	EPSD	COSMIC	37.605	Down-regulation
CAMK_CAMK2_CAMK2D_ST	Q8WZ42	TTN	Q13557	CAMK2D	T23620	S23622C	23622	Missense	proximal	2	no	39.475	35.286	EPSD	COSMIC	37.605	Loss
CAMK_CAMK2_CAMK2D_ST	Q8WZ42	TTN	Q13557	CAMK2D	T23620	D23615E	23615	Missense	distal	-5	no	39.475	39.015	EPSD	COSMIC	37.605	Down-regulation
CAMK_CAMK2_CAMK2D_ST	Q8WZ42	TTN	Q13557	CAMK2D	T24012	H24015Y	24015	Missense	distal	3	no	25.198	39.846	EPSD	COSMIC	37.605	Gain
CAMK_CAMK2_CAMK2D_ST	Q8WZ42	TTN	Q13557	CAMK2D	S24112	L24113I	24113	Missense	proximal	1	no	49.750	57.643	EPSD	COSMIC	37.605	Up-regulation
CAMK_CAMK2_CAMK2D_ST	Q8WZ42	TTN	Q13557	CAMK2D	S24112	L24113P	24113	Missense	proximal	1	no	49.750	46.212	EPSD	COSMIC	37.605	Down-regulation
CAMK_CAMK2_CAMK2D_ST	Q8WZ42	TTN	Q13557	CAMK2D	T24307	L24314F	24314	Missense	distal	7	no	40.364	39.128	EPSD	COSMIC	37.605	Down-regulation
CAMK_CAMK2_CAMK2D_ST	Q8WZ42	TTN	Q13557	CAMK2D	T24307	T24308N	24308	Missense	proximal	1	no	40.364	42.992	EPSD	COSMIC	37.605	Up-regulation
CAMK_CAMK2_CAMK2D_ST	Q8WZ42	TTN	Q13557	CAMK2D	T24316	L24314F	24314	Missense	proximal	-2	no	41.697	41.830	EPSD	COSMIC	37.605	Up-regulation
CAMK_CAMK2_CAMK2D_ST	Q8WZ42	TTN	Q13557	CAMK2D	T24316	Q24321P	24321	Missense	distal	5	no	41.697	42.112	EPSD	COSMIC	37.605	Up-regulation
CAMK_CAMK2_CAMK2D_ST	Q8WZ42	TTN	Q13557	CAMK2D	S24689	A24692V	24692	Missense	distal	3	no	52.555	31.323	EPSD	COSMIC	37.605	Loss
CAMK_CAMK2_CAMK2D_ST	Q8WZ42	TTN	Q13557	CAMK2D	S24689	S24689I	24689	Missense	central	0	yes	52.555	0.000	EPSD	COSMIC	37.605	Loss
CAMK_CAMK2_CAMK2D_ST	Q8WZ42	TTN	Q13557	CAMK2D	S24689	A24692T	24692	Missense	distal	3	no	52.555	39.428	EPSD	COSMIC	37.605	Down-regulation
CAMK_CAMK2_CAMK2D_ST	Q8WZ42	TTN	Q13557	CAMK2D	S24788	G24789R	24789	Missense	proximal	1	no	42.938	47.692	EPSD	COSMIC	37.605	Up-regulation
CAMK_CAMK2_CAMK2D_ST	Q8WZ42	TTN	Q13557	CAMK2D	S24788	C24795R	24795	Missense	distal	7	no	42.938	41.118	EPSD	COSMIC	37.605	Down-regulation
CAMK_CAMK2_CAMK2D_ST	Q8WZ42	TTN	Q13557	CAMK2D	T24801	R24806H	24806	Missense	distal	5	no	48.512	49.314	EPSD	COSMIC	37.605	Up-regulation
CAMK_CAMK2_CAMK2D_ST	Q8WZ42	TTN	Q13557	CAMK2D	T24801	R24806C	24806	Missense	distal	5	no	48.512	47.610	EPSD	COSMIC	37.605	Down-regulation
CAMK_CAMK2_CAMK2D_ST	Q8WZ42	TTN	Q13557	CAMK2D	T24801	R24799C	24799	Missense	proximal	-2	no	48.512	47.467	EPSD	COSMIC	37.605	Down-regulation
CAMK_CAMK2_CAMK2D_ST	Q8WZ42	TTN	Q13557	CAMK2D	T24801	R24804C	24804	Missense	distal	3	no	48.512	51.204	EPSD	COSMIC	37.605	Up-regulation
CAMK_CAMK2_CAMK2D_ST	Q8WZ42	TTN	Q13557	CAMK2D	T24801	C24795R	24795	Missense	distal	-6	no	48.512	51.383	EPSD	COSMIC	37.605	Up-regulation
CAMK_CAMK2_CAMK2D_ST	Q8WZ42	TTN	Q13557	CAMK2D	T24801	K24797N	24797	Missense	distal	-4	no	48.512	44.609	EPSD	COSMIC	37.605	Down-regulation
CAMK_CAMK2_CAMK2D_ST	Q8WZ42	TTN	Q13557	CAMK2D	S25094	S25094L	25094	Missense	central	0	yes	48.404	0.000	EPSD	COSMIC	37.605	Loss
CAMK_CAMK2_CAMK2D_ST	Q8WZ42	TTN	Q13557	CAMK2D	S25094	A25090P	25090	Missense	distal	-4	no	48.404	47.354	EPSD	COSMIC	37.605	Down-regulation
CAMK_CAMK2_CAMK2D_ST	Q8WZ42	TTN	Q13557	CAMK2D	S25094	K25098N	25098	Missense	distal	4	no	48.404	47.989	EPSD	COSMIC	37.605	Down-regulation
CAMK_CAMK2_CAMK2D_ST	Q8WZ42	TTN	Q13557	CAMK2D	S25094	C25096Y	25096	Missense	proximal	2	no	48.404	45.553	EPSD	COSMIC	37.605	Down-regulation
CAMK_CAMK2_CAMK2D_ST	Q8WZ42	TTN	Q13557	CAMK2D	T25283	V25285I	25285	Missense	proximal	2	no	35.534	40.849	EPSD	COSMIC	37.605	Gain
CAMK_CAMK2_CAMK2D_ST	Q8WZ42	TTN	Q13557	CAMK2D	T25389	A25384T	25384	Missense	distal	-5	no	41.908	40.824	EPSD	COSMIC	37.605	Down-regulation
CAMK_CAMK2_CAMK2D_ST	Q8WZ42	TTN	Q13557	CAMK2D	T25389	R25388G	25388	Missense	proximal	-1	no	41.908	39.952	EPSD	COSMIC	37.605	Down-regulation
CAMK_CAMK2_CAMK2D_ST	Q8WZ42	TTN	Q13557	CAMK2D	T25398	F25404L	25404	Missense	distal	6	no	38.862	39.223	EPSD	COSMIC	37.605	Up-regulation
CAMK_CAMK2_CAMK2D_ST	Q8WZ42	TTN	Q13557	CAMK2D	S25442	V25440I	25440	Missense	proximal	-2	no	41.732	41.969	EPSD	COSMIC	37.605	Up-regulation
CAMK_CAMK2_CAMK2D_ST	Q8WZ42	TTN	Q13557	CAMK2D	S25617	I25623N	25623	Missense	distal	6	no	43.639	45.479	EPSD	COSMIC	37.605	Up-regulation
CAMK_CAMK2_CAMK2D_ST	Q8WZ42	TTN	Q13557	CAMK2D	S25617	S25619N	25619	Missense	proximal	2	no	43.639	40.025	EPSD	COSMIC	37.605	Down-regulation
CAMK_CAMK2_CAMK2D_ST	Q8WZ42	TTN	Q13557	CAMK2D	T25891	L25888I	25888	Missense	distal	-3	no	35.265	43.998	EPSD	COSMIC	37.605	Gain
CAMK_CAMK2_CAMK2D_ST	Q8WZ42	TTN	Q13557	CAMK2D	T25891	D25885N	25885	Missense	distal	-6	no	35.265	48.427	EPSD	COSMIC	37.605	Gain
CAMK_CAMK2_CAMK2D_ST	Q8WZ42	TTN	Q13557	CAMK2D	T25891	T25884M	25884	Missense	distal	-7	no	35.265	38.478	EPSD	COSMIC	37.605	Gain
CAMK_CAMK2_CAMK2D_ST	Q8WZ42	TTN	Q13557	CAMK2D	T26133	N26131I	26131	Missense	proximal	-2	no	47.026	46.921	EPSD	COSMIC	37.605	Down-regulation
CAMK_CAMK2_CAMK2D_ST	Q8WZ42	TTN	Q13557	CAMK2D	T26133	A26128V	26128	Missense	distal	-5	no	47.026	46.194	EPSD	COSMIC	37.605	Down-regulation
CAMK_CAMK2_CAMK2D_ST	Q8WZ42	TTN	Q13557	CAMK2D	T26133	K26139R	26139	Missense	distal	6	no	47.026	47.680	EPSD	COSMIC	37.605	Up-regulation
CAMK_CAMK2_CAMK2D_ST	Q8WZ42	TTN	Q13557	CAMK2D	T26366	R26367W	26367	Missense	proximal	1	no	39.278	33.761	EPSD	COSMIC	37.605	Loss
CAMK_CAMK2_CAMK2D_ST	Q8WZ42	TTN	Q13557	CAMK2D	T26366	R26367Q	26367	Missense	proximal	1	no	39.278	34.116	EPSD	COSMIC	37.605	Loss
CAMK_CAMK2_CAMK2D_ST	Q8WZ42	TTN	Q13557	CAMK2D	S26380	K26374N	26374	Missense	distal	-6	no	33.893	42.859	EPSD	COSMIC	37.605	Gain
CAMK_CAMK2_CAMK2D_ST	Q8WZ42	TTN	Q13557	CAMK2D	T26480	R26477C	26477	Missense	distal	-3	no	51.713	22.211	EPSD	COSMIC	37.605	Loss
CAMK_CAMK2_CAMK2D_ST	Q8WZ42	TTN	Q13557	CAMK2D	T26480	I26475T	26475	Missense	distal	-5	no	51.713	52.873	EPSD	COSMIC	37.605	Up-regulation
CAMK_CAMK2_CAMK2D_ST	Q8WZ42	TTN	Q13557	CAMK2D	T26480	E26483Q	26483	Missense	distal	3	no	51.713	46.114	EPSD	COSMIC	37.605	Down-regulation
CAMK_CAMK2_CAMK2D_ST	Q8WZ42	TTN	Q13557	CAMK2D	S26576	D26570N	26570	Missense	distal	-6	no	24.994	38.156	EPSD	COSMIC	37.605	Gain
CAMK_CAMK2_CAMK2D_ST	Q8WZ42	TTN	Q13557	CAMK2D	T26784	L26791P	26791	Missense	distal	7	no	41.023	40.106	EPSD	COSMIC	37.605	Down-regulation
CAMK_CAMK2_CAMK2D_ST	Q8WZ42	TTN	Q13557	CAMK2D	T26784	R26781S	26781	Missense	distal	-3	no	41.023	24.849	EPSD	COSMIC	37.605	Loss
CAMK_CAMK2_CAMK2D_ST	Q8WZ42	TTN	Q13557	CAMK2D	T26784	T26790S	26790	Missense	distal	6	no	41.023	41.653	EPSD	COSMIC	37.605	Up-regulation
CAMK_CAMK2_CAMK2D_ST	Q8WZ42	TTN	Q13557	CAMK2D	T26784	Y26787C	26787	Missense	distal	3	no	41.023	38.613	EPSD	COSMIC	37.605	Down-regulation
CAMK_CAMK2_CAMK2D_ST	Q8WZ42	TTN	Q13557	CAMK2D	T26972	D26966N	26966	Missense	distal	-6	no	54.033	67.195	EPSD	COSMIC	37.605	Up-regulation
CAMK_CAMK2_CAMK2D_ST	Q8WZ42	TTN	Q13557	CAMK2D	T27217	S27220F	27220	Missense	distal	3	no	48.964	43.141	EPSD	COSMIC	37.605	Down-regulation
CAMK_CAMK2_CAMK2D_ST	Q8WZ42	TTN	Q13557	CAMK2D	T27217	T27217I	27217	Missense	central	0	yes	48.964	0.000	EPSD	COSMIC	37.605	Loss
CAMK_CAMK2_CAMK2D_ST	Q8WZ42	TTN	Q13557	CAMK2D	T27217	V27222A	27222	Missense	distal	5	no	48.964	49.176	EPSD	COSMIC	37.605	Up-regulation
CAMK_CAMK2_CAMK2D_ST	Q8WZ42	TTN	Q13557	CAMK2D	S27428	P27433A	27433	Missense	distal	5	no	37.983	37.299	EPSD	COSMIC	37.605	Loss
CAMK_CAMK2_CAMK2D_ST	Q8WZ42	TTN	Q13557	CAMK2D	T27562	Y27567F	27567	Missense	distal	5	no	44.653	42.551	EPSD	COSMIC	37.605	Down-regulation
CAMK_CAMK2_CAMK2D_ST	Q8WZ42	TTN	Q13557	CAMK2D	T27562	E27565K	27565	Missense	distal	3	no	44.653	38.634	EPSD	COSMIC	37.605	Down-regulation
CAMK_CAMK2_CAMK2D_ST	Q8WZ42	TTN	Q13557	CAMK2D	T27562	E27566K	27566	Missense	distal	4	no	44.653	45.108	EPSD	COSMIC	37.605	Up-regulation
CAMK_CAMK2_CAMK2D_ST	Q8WZ42	TTN	Q13557	CAMK2D	S27640	D27637V	27637	Missense	distal	-3	no	17.957	42.257	EPSD	COSMIC	37.605	Gain
CAMK_CAMK2_CAMK2D_ST	Q8WZ42	TTN	Q13557	CAMK2D	S27757	G27758R	27758	Missense	proximal	1	no	39.512	44.266	EPSD	COSMIC	37.605	Up-regulation
CAMK_CAMK2_CAMK2D_ST	Q8WZ42	TTN	Q13557	CAMK2D	S27757	Q27753K	27753	Missense	distal	-4	no	39.512	41.286	EPSD	COSMIC	37.605	Up-regulation
CAMK_CAMK2_CAMK2D_ST	Q8WZ42	TTN	Q13557	CAMK2D	S27757	Q27753R	27753	Missense	distal	-4	no	39.512	42.508	EPSD	COSMIC	37.605	Up-regulation
CAMK_CAMK2_CAMK2D_ST	Q8WZ42	TTN	Q13557	CAMK2D	S27867	G27868R	27868	Missense	proximal	1	no	33.351	38.105	EPSD	COSMIC;CCLE	37.605	Gain
CAMK_CAMK2_CAMK2D_ST	Q8WZ42	TTN	Q13557	CAMK2D	T28145	V28149A	28149	Missense	distal	4	no	41.140	41.781	EPSD	COSMIC	37.605	Up-regulation
CAMK_CAMK2_CAMK2D_ST	Q8WZ42	TTN	Q13557	CAMK2D	T28145	E28138D	28138	Missense	distal	-7	no	41.140	40.822	EPSD	COSMIC	37.605	Down-regulation
CAMK_CAMK2_CAMK2D_ST	Q8WZ42	TTN	Q13557	CAMK2D	T28145	W28140R	28140	Missense	distal	-5	no	41.140	39.204	EPSD	COSMIC;CCLE	37.605	Down-regulation
CAMK_CAMK2_CAMK2D_ST	Q8WZ42	TTN	Q13557	CAMK2D	T28145	V28143L	28143	Missense	proximal	-2	no	41.140	40.848	EPSD	COSMIC	37.605	Down-regulation
CAMK_CAMK2_CAMK2D_ST	Q8WZ42	TTN	Q13557	CAMK2D	T28145	T28145I	28145	Missense	central	0	yes	41.140	0.000	EPSD	COSMIC	37.605	Loss
CAMK_CAMK2_CAMK2D_ST	Q8WZ42	TTN	Q13557	CAMK2D	T28145	V28143M	28143	Missense	proximal	-2	no	41.140	41.525	EPSD	COSMIC	37.605	Up-regulation
CAMK_CAMK2_CAMK2D_ST	Q8WZ42	TTN	Q13557	CAMK2D	S28397	P28392S	28392	Missense	distal	-5	no	51.215	50.593	EPSD	COSMIC	37.605	Down-regulation
CAMK_CAMK2_CAMK2D_ST	Q8WZ42	TTN	Q13557	CAMK2D	S28397	R28394H	28394	Missense	distal	-3	no	51.215	13.891	EPSD	COSMIC	37.605	Loss
CAMK_CAMK2_CAMK2D_ST	Q8WZ42	TTN	Q13557	CAMK2D	S28397	K28403E	28403	Missense	distal	6	no	51.215	50.668	EPSD	COSMIC	37.605	Down-regulation
CAMK_CAMK2_CAMK2D_ST	Q8WZ42	TTN	Q13557	CAMK2D	S28397	I28393L	28393	Missense	distal	-4	no	51.215	49.541	EPSD	COSMIC	37.605	Down-regulation
CAMK_CAMK2_CAMK2D_ST	Q8WZ42	TTN	Q13557	CAMK2D	S28397	D28395N	28395	Missense	proximal	-2	no	51.215	51.923	EPSD	COSMIC	37.605	Up-regulation
CAMK_CAMK2_CAMK2D_ST	Q8WZ42	TTN	Q13557	CAMK2D	S28456	E28459Q	28459	Missense	distal	3	no	53.062	47.463	EPSD	COSMIC	37.605	Down-regulation
CAMK_CAMK2_CAMK2D_ST	Q8WZ42	TTN	Q13557	CAMK2D	S28636	T28641M	28641	Missense	distal	5	no	44.404	41.917	EPSD	COSMIC	37.605	Down-regulation
CAMK_CAMK2_CAMK2D_ST	Q8WZ42	TTN	Q13557	CAMK2D	S28636	S28636P	28636	Missense	central	0	yes	44.404	0.000	EPSD	COSMIC	37.605	Loss
CAMK_CAMK2_CAMK2D_ST	Q8WZ42	TTN	Q13557	CAMK2D	S28736	L28729I	28729	Missense	distal	-7	no	41.916	41.342	EPSD	COSMIC	37.605	Down-regulation
CAMK_CAMK2_CAMK2D_ST	Q8WZ42	TTN	Q13557	CAMK2D	S28736	R28741K	28741	Missense	distal	5	no	41.916	41.470	EPSD	COSMIC	37.605	Down-regulation
CAMK_CAMK2_CAMK2D_ST	Q8WZ42	TTN	Q13557	CAMK2D	S28739	A28745G	28745	Missense	distal	6	no	47.743	46.293	EPSD	COSMIC	37.605	Down-regulation
CAMK_CAMK2_CAMK2D_ST	Q8WZ42	TTN	Q13557	CAMK2D	S28739	R28741K	28741	Missense	proximal	2	no	47.743	44.618	EPSD	COSMIC	37.605	Down-regulation
CAMK_CAMK2_CAMK2D_ST	Q8WZ42	TTN	Q13557	CAMK2D	T29039	E29034K	29034	Missense	distal	-5	no	45.289	44.113	EPSD	COSMIC	37.605	Down-regulation
CAMK_CAMK2_CAMK2D_ST	Q8WZ42	TTN	Q13557	CAMK2D	T29039	A29040D	29040	Missense	proximal	1	no	45.289	46.193	EPSD	COSMIC	37.605	Up-regulation
CAMK_CAMK2_CAMK2D_ST	Q8WZ42	TTN	Q13557	CAMK2D	S29421	E29427K	29427	Missense	distal	6	no	41.183	41.730	EPSD	COSMIC	37.605	Up-regulation
CAMK_CAMK2_CAMK2D_ST	Q8WZ42	TTN	Q13557	CAMK2D	S29421	S29426R	29426	Missense	distal	5	no	41.183	41.602	EPSD	COSMIC	37.605	Up-regulation
CAMK_CAMK2_CAMK2D_ST	Q8WZ42	TTN	Q13557	CAMK2D	T29539	E29542Q	29542	Missense	distal	3	no	46.173	40.574	EPSD	COSMIC	37.605	Down-regulation
CAMK_CAMK2_CAMK2D_ST	Q8WZ42	TTN	Q13557	CAMK2D	T29539	R29534H	29534	Missense	distal	-5	no	46.173	48.078	EPSD	COSMIC	37.605	Up-regulation
CAMK_CAMK2_CAMK2D_ST	Q8WZ42	TTN	Q13557	CAMK2D	T29539	T29539A	29539	Missense	central	0	yes	46.173	0.000	EPSD	COSMIC	37.605	Loss
CAMK_CAMK2_CAMK2D_ST	Q8WZ42	TTN	Q13557	CAMK2D	T29539	V29532A	29532	Missense	distal	-7	no	46.173	48.138	EPSD	COSMIC	37.605	Up-regulation
CAMK_CAMK2_CAMK2D_ST	Q8WZ42	TTN	Q13557	CAMK2D	T29593	P29591L	29591	Missense	proximal	-2	no	46.868	46.396	EPSD	COSMIC	37.605	Down-regulation
CAMK_CAMK2_CAMK2D_ST	Q8WZ42	TTN	Q13557	CAMK2D	T29593	G29600D	29600	Missense	distal	7	no	46.868	47.860	EPSD	COSMIC	37.605	Up-regulation
CAMK_CAMK2_CAMK2D_ST	Q8WZ42	TTN	Q13557	CAMK2D	T29626	D29628G	29628	Missense	proximal	2	no	54.274	48.543	EPSD	COSMIC	37.605	Down-regulation
CAMK_CAMK2_CAMK2D_ST	Q8WZ42	TTN	Q13557	CAMK2D	T29626	T29625S	29625	Missense	proximal	-1	no	54.274	54.116	EPSD	COSMIC	37.605	Down-regulation
CAMK_CAMK2_CAMK2D_ST	Q8WZ42	TTN	Q13557	CAMK2D	S29637	D29636N	29636	Missense	proximal	-1	no	37.671	39.657	EPSD	COSMIC	37.605	Up-regulation
CAMK_CAMK2_CAMK2D_ST	Q8WZ42	TTN	Q13557	CAMK2D	S29637	G29643E	29643	Missense	distal	6	no	37.671	35.999	EPSD	COSMIC	37.605	Loss
CAMK_CAMK2_CAMK2D_ST	Q8WZ42	TTN	Q13557	CAMK2D	S29642	D29636N	29636	Missense	distal	-6	no	38.980	52.142	EPSD	COSMIC	37.605	Up-regulation
CAMK_CAMK2_CAMK2D_ST	Q8WZ42	TTN	Q13557	CAMK2D	S29642	G29643E	29643	Missense	proximal	1	no	38.980	37.983	EPSD	COSMIC	37.605	Down-regulation
CAMK_CAMK2_CAMK2D_ST	Q8WZ42	TTN	Q13557	CAMK2D	S29642	Y29645H	29645	Missense	distal	3	no	38.980	24.332	EPSD	COSMIC	37.605	Loss
CAMK_CAMK2_CAMK2D_ST	Q8WZ42	TTN	Q13557	CAMK2D	S29720	K29723N	29723	Missense	distal	3	no	45.048	46.910	EPSD	COSMIC	37.605	Up-regulation
CAMK_CAMK2_CAMK2D_ST	Q8WZ42	TTN	Q13557	CAMK2D	S29720	V29722D	29722	Missense	proximal	2	no	45.048	57.353	EPSD	COSMIC;CCLE	37.605	Up-regulation
CAMK_CAMK2_CAMK2D_ST	Q8WZ42	TTN	Q13557	CAMK2D	S29720	R29724C	29724	Missense	distal	4	no	45.048	46.263	EPSD	COSMIC	37.605	Up-regulation
CAMK_CAMK2_CAMK2D_ST	Q8WZ42	TTN	Q13557	CAMK2D	S29720	S29721N	29721	Missense	proximal	1	no	45.048	45.274	EPSD	COSMIC	37.605	Up-regulation
CAMK_CAMK2_CAMK2D_ST	Q8WZ42	TTN	Q13557	CAMK2D	S29720	V29722L	29722	Missense	proximal	2	no	45.048	50.991	EPSD	COSMIC	37.605	Up-regulation
CAMK_CAMK2_CAMK2D_ST	Q8WZ42	TTN	Q13557	CAMK2D	S29720	S29720F	29720	Missense	central	0	yes	45.048	0.000	EPSD	COSMIC	37.605	Loss
CAMK_CAMK2_CAMK2D_ST	Q8WZ42	TTN	Q13557	CAMK2D	T29725	K29723N	29723	Missense	proximal	-2	no	38.274	38.750	EPSD	COSMIC	37.605	Up-regulation
CAMK_CAMK2_CAMK2D_ST	Q8WZ42	TTN	Q13557	CAMK2D	T29725	V29722D	29722	Missense	distal	-3	no	38.274	13.975	EPSD	COSMIC;CCLE	37.605	Loss
CAMK_CAMK2_CAMK2D_ST	Q8WZ42	TTN	Q13557	CAMK2D	T29725	R29724C	29724	Missense	proximal	-1	no	38.274	35.880	EPSD	COSMIC	37.605	Loss
CAMK_CAMK2_CAMK2D_ST	Q8WZ42	TTN	Q13557	CAMK2D	T29725	T29730A	29730	Missense	distal	5	no	38.274	39.339	EPSD	COSMIC	37.605	Up-regulation
CAMK_CAMK2_CAMK2D_ST	Q8WZ42	TTN	Q13557	CAMK2D	T29725	S29721N	29721	Missense	distal	-4	no	38.274	35.395	EPSD	COSMIC	37.605	Loss
CAMK_CAMK2_CAMK2D_ST	Q8WZ42	TTN	Q13557	CAMK2D	T29725	V29722L	29722	Missense	distal	-3	no	38.274	28.823	EPSD	COSMIC	37.605	Loss
CAMK_CAMK2_CAMK2D_ST	Q8WZ42	TTN	Q13557	CAMK2D	T29725	S29720F	29720	Missense	distal	-5	no	38.274	39.469	EPSD	COSMIC	37.605	Up-regulation
CAMK_CAMK2_CAMK2D_ST	Q8WZ42	TTN	Q13557	CAMK2D	T30225	D30224E	30224	Missense	proximal	-1	no	37.655	40.012	EPSD	COSMIC	37.605	Up-regulation
CAMK_CAMK2_CAMK2D_ST	Q8WZ42	TTN	Q13557	CAMK2D	T30225	R30226M	30226	Missense	proximal	1	no	37.655	38.378	EPSD	COSMIC	37.605	Up-regulation
CAMK_CAMK2_CAMK2D_ST	Q8WZ42	TTN	Q13557	CAMK2D	T30320	R30325T	30325	Missense	distal	5	no	51.220	51.907	EPSD	COSMIC	37.605	Up-regulation
CAMK_CAMK2_CAMK2D_ST	Q8WZ42	TTN	Q13557	CAMK2D	T30320	R30325G	30325	Missense	distal	5	no	51.220	51.752	EPSD	COSMIC	37.605	Up-regulation
CAMK_CAMK2_CAMK2D_ST	Q8WZ42	TTN	Q13557	CAMK2D	T30384	G30388M	30388	Missense	distal	4	no	46.697	46.630	EPSD	COSMIC	37.605	Down-regulation
CAMK_CAMK2_CAMK2D_ST	Q8WZ42	TTN	Q13557	CAMK2D	T30713	E30710Q	30710	Missense	distal	-3	no	9.211	43.679	EPSD	COSMIC	37.605	Gain
CAMK_CAMK2_CAMK2D_ST	Q8WZ42	TTN	Q13557	CAMK2D	S30812	G30805S	30805	Missense	distal	-7	no	45.580	48.948	EPSD	COSMIC	37.605	Up-regulation
CAMK_CAMK2_CAMK2D_ST	Q8WZ42	TTN	Q13557	CAMK2D	S30812	K30819E	30819	Missense	distal	7	no	45.580	45.502	EPSD	COSMIC	37.605	Down-regulation
CAMK_CAMK2_CAMK2D_ST	Q8WZ42	TTN	Q13557	CAMK2D	S30812	G30805C	30805	Missense	distal	-7	no	45.580	52.726	EPSD	COSMIC	37.605	Up-regulation
CAMK_CAMK2_CAMK2D_ST	Q8WZ42	TTN	Q13557	CAMK2D	T31011	T31012I	31012	Missense	proximal	1	no	38.227	48.427	EPSD	COSMIC	37.605	Up-regulation
CAMK_CAMK2_CAMK2D_ST	Q8WZ42	TTN	Q13557	CAMK2D	T31011	E31018K	31018	Missense	distal	7	no	38.227	38.306	EPSD	COSMIC	37.605	Up-regulation
CAMK_CAMK2_CAMK2D_ST	Q8WZ42	TTN	Q13557	CAMK2D	T31011	E31018D	31018	Missense	distal	7	no	38.227	38.577	EPSD	COSMIC	37.605	Up-regulation
CAMK_CAMK2_CAMK2D_ST	Q8WZ42	TTN	Q13557	CAMK2D	T31011	E31018Q	31018	Missense	distal	7	no	38.227	37.080	EPSD	COSMIC	37.605	Loss
CAMK_CAMK2_CAMK2D_ST	Q8WZ42	TTN	Q13557	CAMK2D	T31020	T31022A	31022	Missense	proximal	2	no	37.935	42.587	EPSD	COSMIC	37.605	Up-regulation
CAMK_CAMK2_CAMK2D_ST	Q8WZ42	TTN	Q13557	CAMK2D	T31020	T31020N	31020	Missense	central	0	yes	37.935	0.000	EPSD	COSMIC;CCLE	37.605	Loss
CAMK_CAMK2_CAMK2D_ST	Q8WZ42	TTN	Q13557	CAMK2D	T31020	P31025S	31025	Missense	distal	5	no	37.935	35.082	EPSD	COSMIC	37.605	Loss
CAMK_CAMK2_CAMK2D_ST	Q8WZ42	TTN	Q13557	CAMK2D	T31020	T31022S	31022	Missense	proximal	2	no	37.935	41.207	EPSD	COSMIC	37.605	Up-regulation
CAMK_CAMK2_CAMK2D_ST	Q8WZ42	TTN	Q13557	CAMK2D	T31020	L31021I	31021	Missense	proximal	1	no	37.935	45.827	EPSD	COSMIC	37.605	Up-regulation
CAMK_CAMK2_CAMK2D_ST	Q8WZ42	TTN	Q13557	CAMK2D	T31020	E31018K	31018	Missense	proximal	-2	no	37.935	38.173	EPSD	COSMIC	37.605	Up-regulation
CAMK_CAMK2_CAMK2D_ST	Q8WZ42	TTN	Q13557	CAMK2D	T31020	E31018D	31018	Missense	proximal	-2	no	37.935	37.941	EPSD	COSMIC	37.605	Up-regulation
CAMK_CAMK2_CAMK2D_ST	Q8WZ42	TTN	Q13557	CAMK2D	T31020	E31018Q	31018	Missense	proximal	-2	no	37.935	38.404	EPSD	COSMIC	37.605	Up-regulation
CAMK_CAMK2_CAMK2D_ST	Q8WZ42	TTN	Q13557	CAMK2D	T31022	T31022A	31022	Missense	central	0	yes	43.814	0.000	EPSD	COSMIC	37.605	Loss
CAMK_CAMK2_CAMK2D_ST	Q8WZ42	TTN	Q13557	CAMK2D	T31022	T31020N	31020	Missense	proximal	-2	no	43.814	44.898	EPSD	COSMIC;CCLE	37.605	Up-regulation
CAMK_CAMK2_CAMK2D_ST	Q8WZ42	TTN	Q13557	CAMK2D	T31022	P31025S	31025	Missense	distal	3	no	43.814	45.086	EPSD	COSMIC	37.605	Up-regulation
CAMK_CAMK2_CAMK2D_ST	Q8WZ42	TTN	Q13557	CAMK2D	T31022	L31021I	31021	Missense	proximal	-1	no	43.814	44.445	EPSD	COSMIC	37.605	Up-regulation
CAMK_CAMK2_CAMK2D_ST	Q8WZ42	TTN	Q13557	CAMK2D	T31022	E31018K	31018	Missense	distal	-4	no	43.814	47.069	EPSD	COSMIC	37.605	Up-regulation
CAMK_CAMK2_CAMK2D_ST	Q8WZ42	TTN	Q13557	CAMK2D	T31022	E31018D	31018	Missense	distal	-4	no	43.814	44.205	EPSD	COSMIC	37.605	Up-regulation
CAMK_CAMK2_CAMK2D_ST	Q8WZ42	TTN	Q13557	CAMK2D	T31022	E31018Q	31018	Missense	distal	-4	no	43.814	45.295	EPSD	COSMIC	37.605	Up-regulation
CAMK_CAMK2_CAMK2D_ST	Q8WZ42	TTN	Q13557	CAMK2D	S31105	D31103N	31103	Missense	proximal	-2	no	43.194	43.902	EPSD	COSMIC	37.605	Up-regulation
CAMK_CAMK2_CAMK2D_ST	Q8WZ42	TTN	Q13557	CAMK2D	S31105	K31099E	31099	Missense	distal	-6	no	43.194	45.177	EPSD	COSMIC	37.605	Up-regulation
CAMK_CAMK2_CAMK2D_ST	Q8WZ42	TTN	Q13557	CAMK2D	T31204	I31205T	31205	Missense	proximal	1	no	47.250	37.050	EPSD	COSMIC	37.605	Loss
CAMK_CAMK2_CAMK2D_ST	Q8WZ42	TTN	Q13557	CAMK2D	T31204	V31197E	31197	Missense	distal	-7	no	47.250	47.282	EPSD	COSMIC	37.605	Up-regulation
CAMK_CAMK2_CAMK2D_ST	Q8WZ42	TTN	Q13557	CAMK2D	T31204	K31199N	31199	Missense	distal	-5	no	47.250	48.927	EPSD	COSMIC	37.605	Up-regulation
CAMK_CAMK2_CAMK2D_ST	Q8WZ42	TTN	Q13557	CAMK2D	T31313	T31314S	31314	Missense	proximal	1	no	41.906	44.308	EPSD	COSMIC	37.605	Up-regulation
CAMK_CAMK2_CAMK2D_ST	Q8WZ42	TTN	Q13557	CAMK2D	T31313	M31315V	31315	Missense	proximal	2	no	41.906	40.333	EPSD	COSMIC	37.605	Down-regulation
CAMK_CAMK2_CAMK2D_ST	Q8WZ42	TTN	Q13557	CAMK2D	T31516	T31514A	31514	Missense	proximal	-2	no	45.061	45.528	EPSD	COSMIC	37.605	Up-regulation
CAMK_CAMK2_CAMK2D_ST	Q8WZ42	TTN	Q13557	CAMK2D	T31764	V31769I	31769	Missense	distal	5	no	40.983	39.737	EPSD	COSMIC	37.605	Down-regulation
CAMK_CAMK2_CAMK2D_ST	Q8WZ42	TTN	Q13557	CAMK2D	T31764	C31768Y	31768	Missense	distal	4	no	40.983	39.208	EPSD	COSMIC	37.605	Down-regulation
CAMK_CAMK2_CAMK2D_ST	Q8WZ42	TTN	Q13557	CAMK2D	T31764	I31760V	31760	Missense	distal	-4	no	40.983	43.373	EPSD	COSMIC	37.605	Up-regulation
CAMK_CAMK2_CAMK2D_ST	Q8WZ42	TTN	Q13557	CAMK2D	T31764	T31764I	31764	Missense	central	0	yes	40.983	0.000	EPSD	COSMIC	37.605	Loss
CAMK_CAMK2_CAMK2D_ST	Q8WZ42	TTN	Q13557	CAMK2D	S31800	T31802S	31802	Missense	proximal	2	no	39.180	42.451	EPSD	COSMIC	37.605	Up-regulation
CAMK_CAMK2_CAMK2D_ST	Q8WZ42	TTN	Q13557	CAMK2D	S32008	V32005A	32005	Missense	distal	-3	no	46.188	32.616	EPSD	COSMIC	37.605	Loss
CAMK_CAMK2_CAMK2D_ST	Q8WZ42	TTN	Q13557	CAMK2D	S32008	R32007H	32007	Missense	proximal	-1	no	46.188	41.710	EPSD	COSMIC	37.605	Down-regulation
CAMK_CAMK2_CAMK2D_ST	Q8WZ42	TTN	Q13557	CAMK2D	S32008	R32007C	32007	Missense	proximal	-1	no	46.188	43.794	EPSD	COSMIC	37.605	Down-regulation
CAMK_CAMK2_CAMK2D_ST	Q8WZ42	TTN	Q13557	CAMK2D	S32162	E32157Q	32157	Missense	distal	-5	no	54.358	52.940	EPSD	COSMIC	37.605	Down-regulation
CAMK_CAMK2_CAMK2D_ST	Q8WZ42	TTN	Q13557	CAMK2D	S32312	T32308I	32308	Missense	distal	-4	no	46.730	45.376	EPSD	COSMIC	37.605	Down-regulation
CAMK_CAMK2_CAMK2D_ST	Q8WZ42	TTN	Q13557	CAMK2D	T32609	R32606H	32606	Missense	distal	-3	no	45.684	8.359	EPSD	COSMIC	37.605	Loss
CAMK_CAMK2_CAMK2D_ST	Q8WZ42	TTN	Q13557	CAMK2D	T32667	L32674I	32674	Missense	distal	7	no	38.079	37.697	EPSD	COSMIC	37.605	Down-regulation
CAMK_CAMK2_CAMK2D_ST	Q8WZ42	TTN	Q13557	CAMK2D	T32667	D32663E	32663	Missense	distal	-4	no	38.079	37.689	EPSD	COSMIC	37.605	Down-regulation
CAMK_CAMK2_CAMK2D_ST	Q8WZ42	TTN	Q13557	CAMK2D	T32911	R32917H	32917	Missense	distal	6	no	48.992	49.473	EPSD	COSMIC	37.605	Up-regulation
CAMK_CAMK2_CAMK2D_ST	Q8WZ42	TTN	Q13557	CAMK2D	T32998	V32991A	32991	Missense	distal	-7	no	46.829	48.794	EPSD	COSMIC	37.605	Up-regulation
CAMK_CAMK2_CAMK2D_ST	Q8WZ42	TTN	Q13557	CAMK2D	T32998	P32999H	32999	Missense	proximal	1	no	46.829	50.418	EPSD	COSMIC;CCLE	37.605	Up-regulation
CAMK_CAMK2_CAMK2D_ST	Q8WZ42	TTN	Q13557	CAMK2D	T33169	Q33165R	33165	Missense	distal	-4	no	45.214	48.211	EPSD	COSMIC	37.605	Up-regulation
CAMK_CAMK2_CAMK2D_ST	Q8WZ42	TTN	Q13557	CAMK2D	T33169	E33176K	33176	Missense	distal	7	no	45.214	45.293	EPSD	COSMIC	37.605	Up-regulation
CAMK_CAMK2_CAMK2D_ST	Q8WZ42	TTN	Q13557	CAMK2D	T33169	E33167Q	33167	Missense	proximal	-2	no	45.214	45.683	EPSD	COSMIC	37.605	Up-regulation
CAMK_CAMK2_CAMK2D_ST	Q8WZ42	TTN	Q13557	CAMK2D	T33169	E33173K	33173	Missense	distal	4	no	45.214	45.669	EPSD	COSMIC;CCLE	37.605	Up-regulation
CAMK_CAMK2_CAMK2D_ST	Q8WZ42	TTN	Q13557	CAMK2D	T33169	I33174T	33174	Missense	distal	5	no	45.214	45.608	EPSD	COSMIC	37.605	Up-regulation
CAMK_CAMK2_CAMK2D_ST	Q8WZ42	TTN	Q13557	CAMK2D	S33203	R33199Q	33199	Missense	distal	-4	no	48.714	45.717	EPSD	COSMIC	37.605	Down-regulation
CAMK_CAMK2_CAMK2D_ST	Q8WZ42	TTN	Q13557	CAMK2D	S33203	R33199W	33199	Missense	distal	-4	no	48.714	43.955	EPSD	COSMIC	37.605	Down-regulation
CAMK_CAMK2_CAMK2D_ST	Q8WZ42	TTN	Q13557	CAMK2D	S33245	S33250Y	33250	Missense	distal	5	no	45.143	45.386	EPSD	COSMIC	37.605	Up-regulation
CAMK_CAMK2_CAMK2D_ST	Q8WZ42	TTN	Q13557	CAMK2D	S33245	R33242C	33242	Missense	distal	-3	no	45.143	15.640	EPSD	COSMIC	37.605	Loss
CAMK_CAMK2_CAMK2D_ST	Q8WZ42	TTN	Q13557	CAMK2D	S33245	S33245F	33245	Missense	central	0	yes	45.143	0.000	EPSD	COSMIC	37.605	Loss
CAMK_CAMK2_CAMK2D_ST	Q8WZ42	TTN	Q13557	CAMK2D	S33245	P33248T	33248	Missense	distal	3	no	45.143	39.750	EPSD	COSMIC	37.605	Down-regulation
CAMK_CAMK2_CAMK2D_ST	Q8WZ42	TTN	Q13557	CAMK2D	S33245	S33245P	33245	Missense	central	0	yes	45.143	0.000	EPSD	COSMIC	37.605	Loss
CAMK_CAMK2_CAMK2D_ST	Q8WZ42	TTN	Q13557	CAMK2D	S33245	E33239K	33239	Missense	distal	-6	no	45.143	43.159	EPSD	COSMIC	37.605	Down-regulation
CAMK_CAMK2_CAMK2D_ST	Q8WZ42	TTN	Q13557	CAMK2D	S33245	S33247G	33247	Missense	proximal	2	no	45.143	47.223	EPSD	COSMIC	37.605	Up-regulation
CAMK_CAMK2_CAMK2D_ST	Q8WZ42	TTN	Q13557	CAMK2D	S33247	S33250Y	33250	Missense	distal	3	no	43.037	46.483	EPSD	COSMIC	37.605	Up-regulation
CAMK_CAMK2_CAMK2D_ST	Q8WZ42	TTN	Q13557	CAMK2D	S33247	R33242C	33242	Missense	distal	-5	no	43.037	43.337	EPSD	COSMIC	37.605	Up-regulation
CAMK_CAMK2_CAMK2D_ST	Q8WZ42	TTN	Q13557	CAMK2D	S33247	S33245F	33245	Missense	proximal	-2	no	43.037	42.794	EPSD	COSMIC	37.605	Down-regulation
CAMK_CAMK2_CAMK2D_ST	Q8WZ42	TTN	Q13557	CAMK2D	S33247	P33248T	33248	Missense	proximal	1	no	43.037	44.268	EPSD	COSMIC	37.605	Up-regulation
CAMK_CAMK2_CAMK2D_ST	Q8WZ42	TTN	Q13557	CAMK2D	S33247	S33245P	33245	Missense	proximal	-2	no	43.037	43.135	EPSD	COSMIC	37.605	Up-regulation
CAMK_CAMK2_CAMK2D_ST	Q8WZ42	TTN	Q13557	CAMK2D	S33247	S33247G	33247	Missense	central	0	yes	43.037	0.000	EPSD	COSMIC	37.605	Loss
CAMK_CAMK2_CAMK2D_ST	Q8WZ42	TTN	Q13557	CAMK2D	S33254	S33250Y	33250	Missense	distal	-4	no	49.818	52.372	EPSD	COSMIC	37.605	Up-regulation
CAMK_CAMK2_CAMK2D_ST	Q8WZ42	TTN	Q13557	CAMK2D	S33254	P33248T	33248	Missense	distal	-6	no	49.818	47.197	EPSD	COSMIC	37.605	Down-regulation
CAMK_CAMK2_CAMK2D_ST	Q8WZ42	TTN	Q13557	CAMK2D	S33254	S33247G	33247	Missense	distal	-7	no	49.818	46.450	EPSD	COSMIC	37.605	Down-regulation
CAMK_CAMK2_CAMK2D_ST	Q8WZ42	TTN	Q13557	CAMK2D	T33498	E33501Q	33501	Missense	distal	3	no	47.077	41.477	EPSD	COSMIC	37.605	Down-regulation
CAMK_CAMK2_CAMK2D_ST	Q8WZ42	TTN	Q13557	CAMK2D	T33498	G33502S	33502	Missense	distal	4	no	47.077	47.171	EPSD	COSMIC	37.605	Up-regulation
CAMK_CAMK2_CAMK2D_ST	Q8WZ42	TTN	Q13557	CAMK2D	T33498	P33494S	33494	Missense	distal	-4	no	47.077	46.517	EPSD	COSMIC	37.605	Down-regulation
CAMK_CAMK2_CAMK2D_ST	Q8WZ42	TTN	Q13557	CAMK2D	S33529	V33527I	33527	Missense	proximal	-2	no	41.362	41.599	EPSD	COSMIC	37.605	Up-regulation
CAMK_CAMK2_CAMK2D_ST	Q8WZ42	TTN	Q13557	CAMK2D	S33529	G33525E	33525	Missense	distal	-4	no	41.362	39.185	EPSD	COSMIC	37.605	Down-regulation
CAMK_CAMK2_CAMK2D_ST	Q8WZ42	TTN	Q13557	CAMK2D	S33529	R33523C	33523	Missense	distal	-6	no	41.362	38.492	EPSD	COSMIC	37.605	Down-regulation
CAMK_CAMK2_CAMK2D_ST	Q8WZ42	TTN	Q13557	CAMK2D	T33576	Q33569K	33569	Missense	distal	-7	no	33.679	38.515	EPSD	COSMIC	37.605	Gain
CAMK_CAMK2_CAMK2D_ST	Q8WZ42	TTN	Q13557	CAMK2D	S33595	R33599W	33599	Missense	distal	4	no	52.125	50.990	EPSD	COSMIC	37.605	Down-regulation
CAMK_CAMK2_CAMK2D_ST	Q8WZ42	TTN	Q13557	CAMK2D	S33595	R33599Q	33599	Missense	distal	4	no	52.125	52.737	EPSD	COSMIC	37.605	Up-regulation
CAMK_CAMK2_CAMK2D_ST	Q8WZ42	TTN	Q13557	CAMK2D	S33602	R33599W	33599	Missense	distal	-3	no	56.021	14.985	EPSD	COSMIC	37.605	Loss
CAMK_CAMK2_CAMK2D_ST	Q8WZ42	TTN	Q13557	CAMK2D	S33602	V33606I	33606	Missense	distal	4	no	56.021	58.214	EPSD	COSMIC	37.605	Up-regulation
CAMK_CAMK2_CAMK2D_ST	Q8WZ42	TTN	Q13557	CAMK2D	S33602	R33599Q	33599	Missense	distal	-3	no	56.021	44.799	EPSD	COSMIC	37.605	Down-regulation
CAMK_CAMK2_CAMK2D_ST	Q8WZ42	TTN	Q13557	CAMK2D	S33614	K33613Q	33613	Missense	proximal	-1	no	46.937	45.449	EPSD	COSMIC	37.605	Down-regulation
CAMK_CAMK2_CAMK2D_ST	Q8WZ42	TTN	Q13557	CAMK2D	S33614	P33620S	33620	Missense	distal	6	no	46.937	41.035	EPSD	COSMIC	37.605	Down-regulation
CAMK_CAMK2_CAMK2D_ST	Q8WZ42	TTN	Q13557	CAMK2D	T33626	T33633I	33633	Missense	distal	7	no	49.680	49.085	EPSD	COSMIC	37.605	Down-regulation
CAMK_CAMK2_CAMK2D_ST	Q8WZ42	TTN	Q13557	CAMK2D	T33626	P33620S	33620	Missense	distal	-6	no	49.680	50.031	EPSD	COSMIC	37.605	Up-regulation
CAMK_CAMK2_CAMK2D_ST	Q8WZ42	TTN	Q13557	CAMK2D	T33843	I33838S	33838	Missense	distal	-5	no	40.687	41.356	EPSD	COSMIC	37.605	Up-regulation
CAMK_CAMK2_CAMK2D_ST	Q8WZ42	TTN	Q13557	CAMK2D	S34266	E34259K	34259	Missense	distal	-7	no	52.585	58.852	EPSD	COSMIC	37.605	Up-regulation
CAMK_CAMK2_CAMK2D_ST	Q8WZ42	TTN	Q13557	CAMK2D	S34266	P34262L	34262	Missense	distal	-4	no	52.585	51.022	EPSD	COSMIC	37.605	Down-regulation
CAMK_CAMK2_CAMK2D_ST	Q14524	SCN5A	Q13557	CAMK2D	T17	E19K	19	Missense	proximal	2	no	50.514	46.197	EPSD	COSMIC	37.605	Down-regulation
CAMK_CAMK2_CAMK2D_ST	Q14524	SCN5A	Q13557	CAMK2D	T17	R14L	14	Missense	distal	-3	no	50.514	28.678	EPSD	COSMIC	37.605	Loss
CAMK_CAMK2_CAMK2D_ST	Q14524	SCN5A	Q13557	CAMK2D	T17	R18L	18	Missense	proximal	1	no	50.514	44.193	EPSD	COSMIC	37.605	Down-regulation
CAMK_CAMK2_CAMK2D_ST	Q14524	SCN5A	Q13557	CAMK2D	T37	S42I	42	Missense	distal	5	no	45.792	46.503	EPSD	COSMIC	37.605	Up-regulation
CAMK_CAMK2_CAMK2D_ST	Q14524	SCN5A	Q13557	CAMK2D	T37	G35S	35	Missense	proximal	-2	no	45.792	45.976	EPSD	COSMIC	37.605	Up-regulation
CAMK_CAMK2_CAMK2D_ST	Q14524	SCN5A	Q13557	CAMK2D	S231	A226G	226	Missense	distal	-5	no	40.944	40.207	EPSD	COSMIC	37.605	Down-regulation
CAMK_CAMK2_CAMK2D_ST	Q14524	SCN5A	Q13557	CAMK2D	S231	R225L	225	Missense	distal	-6	no	40.944	30.544	EPSD	COSMIC	37.605	Loss
CAMK_CAMK2_CAMK2D_ST	Q14524	SCN5A	Q13557	CAMK2D	S497	D498V	498	Missense	proximal	1	no	36.751	42.279	EPSD	COSMIC	37.605	Gain
CAMK_CAMK2_CAMK2D_ST	Q14524	SCN5A	Q13557	CAMK2D	S497	D501Y	501	Missense	distal	4	no	36.751	37.766	EPSD	COSMIC	37.605	Gain
CAMK_CAMK2_CAMK2D_ST	Q14524	SCN5A	Q13557	CAMK2D	S516	T518N	518	Missense	proximal	2	no	71.045	70.702	PhosphoSitePlus;EPSD	COSMIC	37.605	Down-regulation
CAMK_CAMK2_CAMK2D_ST	Q14524	SCN5A	Q13557	CAMK2D	S516	R523C	523	Missense	distal	7	no	71.045	72.865	PhosphoSitePlus;EPSD	COSMIC	37.605	Up-regulation
CAMK_CAMK2_CAMK2D_ST	Q14524	SCN5A	Q13557	CAMK2D	S524	T518N	518	Missense	distal	-6	no	33.971	46.595	EPSD	COSMIC	37.605	Gain
CAMK_CAMK2_CAMK2D_ST	Q14524	SCN5A	Q13557	CAMK2D	S524	S525R	525	Missense	proximal	1	no	33.971	40.197	EPSD	COSMIC	37.605	Gain
CAMK_CAMK2_CAMK2D_ST	Q14524	SCN5A	Q13557	CAMK2D	S528	S525R	525	Missense	distal	-3	no	25.014	41.188	EPSD	COSMIC	37.605	Gain
CAMK_CAMK2_CAMK2D_ST	Q14524	SCN5A	Q13557	CAMK2D	T580	P583S	583	Missense	distal	3	no	36.592	37.864	EPSD	COSMIC	37.605	Gain
CAMK_CAMK2_CAMK2D_ST	Q14524	SCN5A	Q13557	CAMK2D	T580	G579R	579	Missense	proximal	-1	no	36.592	38.548	EPSD	COSMIC	37.605	Gain
CAMK_CAMK2_CAMK2D_ST	Q14524	SCN5A	Q13557	CAMK2D	T594	K591N	591	Missense	distal	-3	no	79.320	71.028	EPSD;PhosphoSitePlus	COSMIC;GDSC;CCLE	37.605	Down-regulation
CAMK_CAMK2_CAMK2D_ST	Q14524	SCN5A	Q13557	CAMK2D	S805	R811C	811	Missense	distal	6	no	38.187	37.511	EPSD	COSMIC	37.605	Loss
CAMK_CAMK2_CAMK2D_ST	Q14524	SCN5A	Q13557	CAMK2D	S1003	G999C	999	Missense	distal	-4	no	42.601	42.778	EPSD	COSMIC	37.605	Up-regulation
CAMK_CAMK2_CAMK2D_ST	Q14524	SCN5A	Q13557	CAMK2D	S1003	Y1009F	1009	Missense	distal	6	no	42.601	42.130	EPSD	COSMIC	37.605	Down-regulation
CAMK_CAMK2_CAMK2D_ST	Q14524	SCN5A	Q13557	CAMK2D	S1003	Y1009S	1009	Missense	distal	6	no	42.601	42.932	EPSD	COSMIC	37.605	Up-regulation
CAMK_CAMK2_CAMK2D_ST	Q14524	SCN5A	Q13557	CAMK2D	S1083	G1085V	1085	Missense	proximal	2	no	51.699	45.124	EPSD	COSMIC	37.605	Down-regulation
CAMK_CAMK2_CAMK2D_ST	Q14524	SCN5A	Q13557	CAMK2D	S1083	G1084S	1084	Missense	proximal	1	no	51.699	50.227	EPSD	COSMIC	37.605	Down-regulation
CAMK_CAMK2_CAMK2D_ST	Q14524	SCN5A	Q13557	CAMK2D	S1083	Q1076K	1076	Missense	distal	-7	no	51.699	56.536	EPSD	COSMIC	37.605	Up-regulation
CAMK_CAMK2_CAMK2D_ST	Q14524	SCN5A	Q13557	CAMK2D	S1083	P1090L	1090	Missense	distal	7	no	51.699	52.616	EPSD	COSMIC	37.605	Up-regulation
CAMK_CAMK2_CAMK2D_ST	Q14524	SCN5A	Q13557	CAMK2D	S1083	G1085D	1085	Missense	proximal	2	no	51.699	57.430	EPSD	COSMIC	37.605	Up-regulation
CAMK_CAMK2_CAMK2D_ST	Q14524	SCN5A	Q13557	CAMK2D	S1925	R1929H	1929	Missense	distal	4	no	51.948	50.375	EPSD	COSMIC	37.605	Down-regulation
CAMK_CAMK2_CAMK2D_ST	Q14524	SCN5A	Q13557	CAMK2D	S1925	A1924V	1924	Missense	proximal	-1	no	51.948	53.207	EPSD	COSMIC	37.605	Up-regulation
CAMK_CAMK2_CAMK2D_ST	Q14524	SCN5A	Q13557	CAMK2D	S1925	L1927F	1927	Missense	proximal	2	no	51.948	44.304	EPSD	COSMIC	37.605	Down-regulation
CAMK_CAMK2_CAMK2D_ST	Q14524	SCN5A	Q13557	CAMK2D	S1937	R1944Q	1944	Missense	distal	7	no	38.552	38.816	EPSD	COSMIC	37.605	Up-regulation
CAMK_CAMK2_CAMK2D_ST	Q14524	SCN5A	Q13557	CAMK2D	S1937	L1936F	1936	Missense	proximal	-1	no	38.552	36.713	EPSD	COSMIC	37.605	Loss
CAMK_CAMK2_CAMK2D_ST	Q14524	SCN5A	Q13557	CAMK2D	S1985	T1984I	1984	Missense	proximal	-1	no	38.885	37.924	EPSD	COSMIC	37.605	Down-regulation
CAMK_CAMK2_CAMK2D_ST	Q14524	SCN5A	Q13557	CAMK2D	S1985	L1988R	1988	Missense	distal	3	no	38.885	47.120	EPSD	COSMIC	37.605	Up-regulation
CAMK_CAMK2_CAMK2D_ST	Q14524	SCN5A	Q13557	CAMK2D	S1985	A1983S	1983	Missense	proximal	-2	no	38.885	39.242	EPSD	COSMIC	37.605	Up-regulation
CAMK_CAMK2_CAMK2D_ST	Q14654	KCNJ11	Q13557	CAMK2D	T224	Q218K	218	Missense	distal	-6	no	73.333	68.060	PhosphoSitePlus	COSMIC	37.605	Down-regulation
CAMK_CAMK2_CAMK2D_ST	Q16625	OCLN	Q13557	CAMK2D	S25	P19Q	19	Missense	distal	-6	no	46.884	53.195	EPSD	COSMIC	37.605	Up-regulation
CAMK_CAMK2_CAMK2D_ST	Q16625	OCLN	Q13557	CAMK2D	S25	P24A	24	Missense	proximal	-1	no	46.884	48.596	EPSD	COSMIC	37.605	Up-regulation
CAMK_CAMK2_CAMK2D_ST	Q16625	OCLN	Q13557	CAMK2D	S25	H21Y	21	Missense	distal	-4	no	46.884	48.126	EPSD	COSMIC	37.605	Up-regulation
CAMK_CAMK2_CAMK2D_ST	Q16625	OCLN	Q13557	CAMK2D	S302	V308M	308	Missense	distal	6	no	39.006	36.623	EPSD	COSMIC;GDSC	37.605	Loss
CAMK_CAMK2_CAMK2D_ST	Q16625	OCLN	Q13557	CAMK2D	S302	K299N	299	Missense	distal	-3	no	39.006	30.714	EPSD	COSMIC	37.605	Loss
CAMK_CAMK2_CAMK2D_ST	Q16625	OCLN	Q13557	CAMK2D	S302	W297C	297	Missense	distal	-5	no	39.006	37.369	EPSD	COSMIC	37.605	Loss
CAMK_CAMK2_CAMK2D_ST	Q16625	OCLN	Q13557	CAMK2D	S302	V308A	308	Missense	distal	6	no	39.006	40.774	EPSD	COSMIC	37.605	Up-regulation
CAMK_CAMK2_CAMK2D_ST	Q16625	OCLN	Q13557	CAMK2D	S302	W297L	297	Missense	distal	-5	no	39.006	37.281	EPSD	COSMIC;GDSC	37.605	Loss
CAMK_CAMK2_CAMK2D_ST	Q16625	OCLN	Q13557	CAMK2D	T305	V308A	308	Missense	distal	3	no	24.548	45.780	EPSD	COSMIC	37.605	Gain
CAMK_CAMK2_CAMK2D_ST	Q16625	OCLN	Q13557	CAMK2D	S370	G372D	372	Missense	proximal	2	no	54.325	60.056	EPSD	COSMIC	37.605	Up-regulation
CAMK_CAMK2_CAMK2D_ST	Q16625	OCLN	Q13557	CAMK2D	T376	G372D	372	Missense	distal	-4	no	41.386	39.599	EPSD	COSMIC	37.605	Down-regulation
CAMK_CAMK2_CAMK2D_ST	O15084	ANKRD28	Q13557	CAMK2D	S194	G196D	196	Missense	proximal	2	no	32.937	38.667	EPSD	COSMIC	37.605	Gain
CAMK_CAMK2_CAMK2D_ST	O15084	ANKRD28	Q13557	CAMK2D	T360	I355T	355	Missense	distal	-5	no	41.180	42.340	EPSD	COSMIC	37.605	Up-regulation
CAMK_CAMK2_CAMK2D_ST	O15084	ANKRD28	Q13557	CAMK2D	T360	L358P	358	Missense	proximal	-2	no	41.180	41.653	EPSD	COSMIC	37.605	Up-regulation
CAMK_CAMK2_CAMK2D_ST	O15084	ANKRD28	Q13557	CAMK2D	T360	G362S	362	Missense	proximal	2	no	41.180	39.100	EPSD	COSMIC	37.605	Down-regulation
CAMK_CAMK2_CAMK2D_ST	O15084	ANKRD28	Q13557	CAMK2D	T982	M984I	984	Missense	proximal	2	no	34.771	38.514	EPSD	COSMIC	37.605	Gain
CAMK_CAMK2_CAMK2D_ST	O15084	ANKRD28	Q13557	CAMK2D	T996	R1002H	1002	Missense	distal	6	no	50.749	51.230	EPSD	COSMIC;GDSC	37.605	Up-regulation
AGC_GRK_GRK_GRK6_ST	P07550	ADRB2	P43250	GRK6	S355	S355F	355	Missense	central	0	yes	113.178	0.000	PhosphoSitePlus;EPSD	COSMIC	74.824	Loss
AGC_GRK_GRK_GRK6_ST	P07550	ADRB2	P43250	GRK6	S356	S355F	355	Missense	proximal	-1	no	113.461	109.783	EPSD;PhosphoSitePlus	COSMIC	74.824	Down-regulation
AGC_GRK_GRK_GRK6_ST	P07550	ADRB2	P43250	GRK6	S364	E369V	369	Missense	distal	5	no	76.187	63.924	EPSD	COSMIC	74.824	Loss
AGC_GRK_GRK_GRK6_ST	P61073	CXCR4	P43250	GRK6	S324	S325R	325	Missense	proximal	1	no	112.493	112.230	PhosphoSitePlus;EPSD	COSMIC	74.824	Down-regulation
AGC_GRK_GRK_GRK6_ST	P61073	CXCR4	P43250	GRK6	S324	L317I	317	Missense	distal	-7	no	112.493	109.800	PhosphoSitePlus;EPSD	COSMIC	74.824	Down-regulation
AGC_GRK_GRK_GRK6_ST	P61073	CXCR4	P43250	GRK6	S324	T318A	318	Missense	distal	-6	no	112.493	111.621	PhosphoSitePlus;EPSD	COSMIC	74.824	Down-regulation
AGC_GRK_GRK_GRK6_ST	P61073	CXCR4	P43250	GRK6	S324	S319F	319	Missense	distal	-5	no	112.493	112.657	PhosphoSitePlus;EPSD	COSMIC	74.824	Up-regulation
AGC_GRK_GRK_GRK6_ST	P61073	CXCR4	P43250	GRK6	S324	S330Y	330	Missense	distal	6	no	112.493	87.608	PhosphoSitePlus;EPSD	COSMIC	74.824	Down-regulation
AGC_GRK_GRK_GRK6_ST	P61073	CXCR4	P43250	GRK6	S324	S324F	324	Missense	central	0	yes	112.493	0.000	PhosphoSitePlus;EPSD	COSMIC	74.824	Loss
AGC_GRK_GRK_GRK6_ST	P61073	CXCR4	P43250	GRK6	S324	L329I	329	Missense	distal	5	no	112.493	107.481	PhosphoSitePlus;EPSD	COSMIC	74.824	Down-regulation
AGC_GRK_GRK_GRK6_ST	P61073	CXCR4	P43250	GRK6	S324	S330C	330	Missense	distal	6	no	112.493	86.571	PhosphoSitePlus;EPSD	COSMIC	74.824	Down-regulation
AGC_GRK_GRK_GRK6_ST	P61073	CXCR4	P43250	GRK6	S324	G323W	323	Missense	proximal	-1	no	112.493	102.265	PhosphoSitePlus;EPSD	COSMIC;CCLE	74.824	Down-regulation
AGC_GRK_GRK_GRK6_ST	P61073	CXCR4	P43250	GRK6	S324	L326P	326	Missense	proximal	2	no	112.493	114.511	PhosphoSitePlus;EPSD	COSMIC	74.824	Up-regulation
AGC_GRK_GRK_GRK6_ST	P61073	CXCR4	P43250	GRK6	S325	S325R	325	Missense	central	0	yes	112.736	0.000	EPSD;PhosphoSitePlus	COSMIC	74.824	Loss
AGC_GRK_GRK_GRK6_ST	P61073	CXCR4	P43250	GRK6	S325	T318A	318	Missense	distal	-7	no	112.736	112.320	EPSD;PhosphoSitePlus	COSMIC	74.824	Down-regulation
AGC_GRK_GRK_GRK6_ST	P61073	CXCR4	P43250	GRK6	S325	S319F	319	Missense	distal	-6	no	112.736	111.079	EPSD;PhosphoSitePlus	COSMIC	74.824	Down-regulation
AGC_GRK_GRK_GRK6_ST	P61073	CXCR4	P43250	GRK6	S325	G332R	332	Missense	distal	7	no	112.736	112.974	EPSD;PhosphoSitePlus	COSMIC	74.824	Up-regulation
AGC_GRK_GRK_GRK6_ST	P61073	CXCR4	P43250	GRK6	S325	G332E	332	Missense	distal	7	no	112.736	112.898	EPSD;PhosphoSitePlus	COSMIC	74.824	Up-regulation
AGC_GRK_GRK_GRK6_ST	P61073	CXCR4	P43250	GRK6	S325	S330Y	330	Missense	distal	5	no	112.736	101.310	EPSD;PhosphoSitePlus	COSMIC	74.824	Down-regulation
AGC_GRK_GRK_GRK6_ST	P61073	CXCR4	P43250	GRK6	S325	S324F	324	Missense	proximal	-1	no	112.736	109.057	EPSD;PhosphoSitePlus	COSMIC	74.824	Down-regulation
AGC_GRK_GRK_GRK6_ST	P61073	CXCR4	P43250	GRK6	S325	L329I	329	Missense	distal	4	no	112.736	112.827	EPSD;PhosphoSitePlus	COSMIC	74.824	Up-regulation
AGC_GRK_GRK_GRK6_ST	P61073	CXCR4	P43250	GRK6	S325	S330C	330	Missense	distal	5	no	112.736	101.626	EPSD;PhosphoSitePlus	COSMIC	74.824	Down-regulation
AGC_GRK_GRK_GRK6_ST	P61073	CXCR4	P43250	GRK6	S325	G323W	323	Missense	proximal	-2	no	112.736	107.345	EPSD;PhosphoSitePlus	COSMIC;CCLE	74.824	Down-regulation
AGC_GRK_GRK_GRK6_ST	P61073	CXCR4	P43250	GRK6	S325	L326P	326	Missense	proximal	1	no	112.736	112.487	EPSD;PhosphoSitePlus	COSMIC	74.824	Down-regulation
AGC_GRK_GRK_GRK6_ST	P61073	CXCR4	P43250	GRK6	S330	S325R	325	Missense	distal	-5	no	99.050	98.753	EPSD	COSMIC	74.824	Down-regulation
AGC_GRK_GRK_GRK6_ST	P61073	CXCR4	P43250	GRK6	S330	G335C	335	Missense	distal	5	no	99.050	85.698	EPSD	COSMIC	74.824	Down-regulation
AGC_GRK_GRK_GRK6_ST	P61073	CXCR4	P43250	GRK6	S330	G332R	332	Missense	proximal	2	no	99.050	99.599	EPSD	COSMIC	74.824	Up-regulation
AGC_GRK_GRK_GRK6_ST	P61073	CXCR4	P43250	GRK6	S330	G332E	332	Missense	proximal	2	no	99.050	100.295	EPSD	COSMIC	74.824	Up-regulation
AGC_GRK_GRK_GRK6_ST	P61073	CXCR4	P43250	GRK6	S330	S330Y	330	Missense	central	0	yes	99.050	0.000	EPSD	COSMIC	74.824	Loss
AGC_GRK_GRK_GRK6_ST	P61073	CXCR4	P43250	GRK6	S330	G336R	336	Missense	distal	6	no	99.050	80.761	EPSD	COSMIC	74.824	Down-regulation
AGC_GRK_GRK_GRK6_ST	P61073	CXCR4	P43250	GRK6	S330	S324F	324	Missense	distal	-6	no	99.050	97.394	EPSD	COSMIC	74.824	Down-regulation
AGC_GRK_GRK_GRK6_ST	P61073	CXCR4	P43250	GRK6	S330	L329I	329	Missense	proximal	-1	no	99.050	96.030	EPSD	COSMIC	74.824	Down-regulation
AGC_GRK_GRK_GRK6_ST	P61073	CXCR4	P43250	GRK6	S330	S330C	330	Missense	central	0	yes	99.050	0.000	EPSD	COSMIC	74.824	Loss
AGC_GRK_GRK_GRK6_ST	P61073	CXCR4	P43250	GRK6	S330	G323W	323	Missense	distal	-7	no	99.050	98.928	EPSD	COSMIC;CCLE	74.824	Down-regulation
AGC_GRK_GRK_GRK6_ST	P61073	CXCR4	P43250	GRK6	S330	L326P	326	Missense	distal	-4	no	99.050	97.822	EPSD	COSMIC	74.824	Down-regulation
AGC_GRK_GRK_GRK6_ST	P61073	CXCR4	P43250	GRK6	S330	G336E	336	Missense	distal	6	no	99.050	97.670	EPSD	COSMIC	74.824	Down-regulation
AGC_GRK_GRK_GRK6_ST	P61073	CXCR4	P43250	GRK6	S339	E345D	345	Missense	distal	6	no	94.179	72.398	EPSD	COSMIC	74.824	Loss
AGC_GRK_GRK_GRK6_ST	P61073	CXCR4	P43250	GRK6	S339	G335C	335	Missense	distal	-4	no	94.179	96.840	EPSD	COSMIC	74.824	Up-regulation
AGC_GRK_GRK_GRK6_ST	P61073	CXCR4	P43250	GRK6	S339	S338A	338	Missense	proximal	-1	no	94.179	93.101	EPSD	COSMIC	74.824	Down-regulation
AGC_GRK_GRK_GRK6_ST	P61073	CXCR4	P43250	GRK6	S339	G332R	332	Missense	distal	-7	no	94.179	97.407	EPSD	COSMIC	74.824	Up-regulation
AGC_GRK_GRK_GRK6_ST	P61073	CXCR4	P43250	GRK6	S339	E345Q	345	Missense	distal	6	no	94.179	81.117	EPSD	COSMIC	74.824	Down-regulation
AGC_GRK_GRK_GRK6_ST	P61073	CXCR4	P43250	GRK6	S339	G332E	332	Missense	distal	-7	no	94.179	96.440	EPSD	COSMIC	74.824	Up-regulation
AGC_GRK_GRK_GRK6_ST	P61073	CXCR4	P43250	GRK6	S339	G336R	336	Missense	distal	-3	no	94.179	98.758	EPSD	COSMIC	74.824	Up-regulation
AGC_GRK_GRK_GRK6_ST	P61073	CXCR4	P43250	GRK6	S339	E343K	343	Missense	distal	4	no	94.179	94.101	EPSD	COSMIC	74.824	Down-regulation
AGC_GRK_GRK_GRK6_ST	P61073	CXCR4	P43250	GRK6	S339	E343G	343	Missense	distal	4	no	94.179	94.147	EPSD	COSMIC	74.824	Down-regulation
AGC_GRK_GRK_GRK6_ST	P61073	CXCR4	P43250	GRK6	S339	S339F	339	Missense	central	0	yes	94.179	0.000	EPSD	COSMIC	74.824	Loss
AGC_GRK_GRK_GRK6_ST	P61073	CXCR4	P43250	GRK6	S339	G336E	336	Missense	distal	-3	no	94.179	93.817	EPSD	COSMIC	74.824	Down-regulation
AGC_GRK_GRK_GRK6_ST	Q15722	LTB4R	P43250	GRK6	T315	G319D	319	Missense	distal	4	no	75.650	75.739	EPSD	COSMIC	74.824	Up-regulation
AGC_GRK_GRK_GRK6_ST	Q15722	LTB4R	P43250	GRK6	S320	G319D	319	Missense	proximal	-1	no	78.310	71.571	EPSD	COSMIC	74.824	Loss
AGC_GRK_GRK_GRK6_ST	Q16625	OCLN	P43250	GRK6	S302	V308A	308	Missense	distal	6	no	64.630	77.419	EPSD	COSMIC	74.824	Gain
AGC_GRK_GRK_GRK6_ST	Q16625	OCLN	P43250	GRK6	S370	G372D	372	Missense	proximal	2	no	75.195	73.850	EPSD	COSMIC	74.824	Loss
AGC_GRK_GRK_GRK6_ST	P08069	IGF1R	P43250	GRK6	S29	P35T	35	Missense	distal	6	no	66.700	76.936	EPSD	COSMIC	74.824	Gain
AGC_GRK_GRK_GRK6_ST	P08069	IGF1R	P43250	GRK6	T1000	E997K	997	Missense	distal	-3	no	70.371	75.829	EPSD	COSMIC	74.824	Gain
AGC_GRK_GRK_GRK6_ST	P08069	IGF1R	P43250	GRK6	S1009	R1003Q	1003	Missense	distal	-6	no	75.726	75.183	EPSD	COSMIC	74.824	Down-regulation
AGC_GRK_GRK_GRK6_ST	P08069	IGF1R	P43250	GRK6	S1009	M1012I	1012	Missense	distal	3	no	75.726	76.523	EPSD	COSMIC	74.824	Up-regulation
AGC_GRK_GRK_GRK6_ST	P08069	IGF1R	P43250	GRK6	S1312	D1318G	1318	Missense	distal	6	no	59.896	83.057	EPSD	COSMIC	74.824	Gain
AGC_GRK_GRK_GRK6_ST	P08069	IGF1R	P43250	GRK6	S1321	G1328V	1328	Missense	distal	7	no	111.736	112.089	PhosphoSitePlus	COSMIC	74.824	Up-regulation
AGC_GRK_GRK_GRK6_ST	P08069	IGF1R	P43250	GRK6	S1321	D1318G	1318	Missense	distal	-3	no	111.736	112.325	PhosphoSitePlus	COSMIC	74.824	Up-regulation
AGC_GRK_GRK_GRK6_ST	P08069	IGF1R	P43250	GRK6	S1321	E1326K	1326	Missense	distal	5	no	111.736	107.293	PhosphoSitePlus	COSMIC	74.824	Down-regulation
AGC_GRK_GRK_GRK6_ST	P08069	IGF1R	P43250	GRK6	S1321	G1322E	1322	Missense	proximal	1	no	111.736	112.824	PhosphoSitePlus	COSMIC	74.824	Up-regulation
AGC_GRK_GRK_GRK6_ST	P08069	IGF1R	P43250	GRK6	S1321	N1327H	1327	Missense	distal	6	no	111.736	94.041	PhosphoSitePlus	COSMIC	74.824	Down-regulation
STE_STE20_YSK_STK25_ST	Q9BSQ5	CCM2	O00506	STK25	S251	S248N	248	Missense	distal	-3	no	1.793	1.765	EPSD	COSMIC	1.379	Down-regulation
STE_STE20_YSK_STK25_ST	Q9BSQ5	CCM2	O00506	STK25	S251	L244M	244	Missense	distal	-7	no	1.793	1.699	EPSD	COSMIC	1.379	Down-regulation
STE_STE20_YSK_STK25_ST	Q9BSQ5	CCM2	O00506	STK25	S251	I257V	257	Missense	distal	6	no	1.793	1.786	EPSD	COSMIC	1.379	Down-regulation
STE_STE20_YSK_STK25_ST	Q9BSQ5	CCM2	O00506	STK25	S251	D250Y	250	Missense	proximal	-1	no	1.793	1.697	EPSD	COSMIC	1.379	Down-regulation
STE_STE20_YSK_STK25_ST	Q9BSQ5	CCM2	O00506	STK25	S251	S251Y	251	Missense	central	0	yes	1.793	0.000	EPSD	COSMIC	1.379	Loss
STE_STE20_YSK_STK25_ST	Q9BSQ5	CCM2	O00506	STK25	S251	D249N	249	Missense	proximal	-2	no	1.793	1.782	EPSD	COSMIC	1.379	Down-regulation
STE_STE20_YSK_STK25_ST	Q9BSQ5	CCM2	O00506	STK25	S251	K258R	258	Missense	distal	7	no	1.793	1.728	EPSD	COSMIC	1.379	Down-regulation
STE_STE20_YSK_STK25_ST	Q9BSQ5	CCM2	O00506	STK25	S384	R378H	378	Missense	distal	-6	no	5.544	5.517	PhosphoSitePlus	COSMIC	1.379	Down-regulation
STE_STE20_YSK_STK25_ST	Q9BSQ5	CCM2	O00506	STK25	S384	S384C	384	Missense	central	0	yes	5.544	0.000	PhosphoSitePlus	COSMIC;CCLE	1.379	Loss
STE_STE20_YSK_STK25_ST	Q9BSQ5	CCM2	O00506	STK25	S384	G379S	379	Missense	distal	-5	no	5.544	5.506	PhosphoSitePlus	COSMIC	1.379	Down-regulation
STE_STE20_YSK_STK25_ST	Q9BSQ5	CCM2	O00506	STK25	S384	G377D	377	Missense	distal	-7	no	5.544	5.548	PhosphoSitePlus	COSMIC	1.379	Up-regulation
STE_STE20_YSK_STK25_ST	Q9BSQ5	CCM2	O00506	STK25	S384	G386C	386	Missense	proximal	2	no	5.544	5.486	PhosphoSitePlus	COSMIC	1.379	Down-regulation
STE_STE20_YSK_STK25_ST	Q9BSQ5	CCM2	O00506	STK25	S384	G386S	386	Missense	proximal	2	no	5.544	5.497	PhosphoSitePlus	COSMIC;CCLE	1.379	Down-regulation
STE_STE20_YSK_STK25_ST	Q9BSQ5	CCM2	O00506	STK25	S384	F385S	385	Missense	proximal	1	no	5.544	5.219	PhosphoSitePlus	COSMIC	1.379	Down-regulation
STE_STE20_YSK_STK25_ST	Q9BSQ5	CCM2	O00506	STK25	S413	A414V	414	Missense	proximal	1	no	1.456	0.986	EPSD	COSMIC	1.379	Loss
STE_STE20_YSK_STK25_ST	Q9BSQ5	CCM2	O00506	STK25	S413	E420K	420	Missense	distal	7	no	1.456	1.561	EPSD	COSMIC;CCLE	1.379	Up-regulation
STE_STE20_YSK_STK25_ST	Q9BSQ5	CCM2	O00506	STK25	S413	G407S	407	Missense	distal	-6	no	1.456	1.383	EPSD	COSMIC;GDSC	1.379	Down-regulation
STE_STE20_YSK_STK25_ST	Q9BSQ5	CCM2	O00506	STK25	S413	G407C	407	Missense	distal	-6	no	1.456	1.433	EPSD	COSMIC	1.379	Down-regulation
STE_STE20_YSK_STK25_ST	Q9BUL8	PDCD10	O00506	STK25	S39	R35Q	35	Missense	distal	-4	no	5.877	5.878	EPSD;PhosphoSitePlus	COSMIC	1.379	Up-regulation
STE_STE20_YSK_STK25_ST	Q9BUL8	PDCD10	O00506	STK25	S39	L44P	44	Missense	distal	5	no	5.877	6.006	EPSD;PhosphoSitePlus	COSMIC;GDSC;CCLE	1.379	Up-regulation
STE_STE20_YSK_STK25_ST	Q9BUL8	PDCD10	O00506	STK25	S39	E32A	32	Missense	distal	-7	no	5.877	5.860	EPSD;PhosphoSitePlus	COSMIC	1.379	Down-regulation
STE_STE20_YSK_STK25_ST	Q9BUL8	PDCD10	O00506	STK25	S39	R45L	45	Missense	distal	6	no	5.877	5.837	EPSD;PhosphoSitePlus	COSMIC	1.379	Down-regulation
STE_STE20_YSK_STK25_ST	Q9BUL8	PDCD10	O00506	STK25	T43	L44P	44	Missense	proximal	1	no	5.560	4.821	PhosphoSitePlus;EPSD	COSMIC;GDSC;CCLE	1.379	Down-regulation
STE_STE20_YSK_STK25_ST	Q9BUL8	PDCD10	O00506	STK25	T43	R45L	45	Missense	proximal	2	no	5.560	5.482	PhosphoSitePlus;EPSD	COSMIC	1.379	Down-regulation
TK_VEGFR_FLT1_Y	P17948	FLT1	P17948	FLT1	Y1053	N1050S	1050	Missense	distal	-3	no	1.851	1.925	EPSD	COSMIC	1.801	Up-regulation
TK_VEGFR_FLT1_Y	P17948	FLT1	P17948	FLT1	Y1053	G1057E	1057	Missense	distal	4	no	1.851	1.836	EPSD	COSMIC	1.801	Down-regulation
TK_VEGFR_FLT1_Y	P17948	FLT1	P17948	FLT1	Y1053	P1051L	1051	Missense	proximal	-2	no	1.851	1.741	EPSD	COSMIC	1.801	Loss
TK_VEGFR_FLT1_Y	P17948	FLT1	P17948	FLT1	Y1053	D1046Y	1046	Missense	distal	-7	no	1.851	1.922	EPSD	COSMIC	1.801	Up-regulation
TK_VEGFR_FLT1_Y	P17948	FLT1	P17948	FLT1	Y1053	R1055T	1055	Missense	proximal	2	no	1.851	1.855	EPSD	COSMIC	1.801	Up-regulation
TK_VEGFR_FLT1_Y	P17948	FLT1	P17948	FLT1	Y1169	V1162L	1162	Missense	distal	-7	no	5.215	5.237	EPSD;PhosphoSitePlus	COSMIC;CCLE	1.801	Up-regulation
TK_VEGFR_FLT1_Y	P17948	FLT1	P17948	FLT1	Y1169	I1170N	1170	Missense	proximal	1	no	5.215	5.220	EPSD;PhosphoSitePlus	COSMIC	1.801	Up-regulation
TK_VEGFR_FLT1_Y	P17948	FLT1	P17948	FLT1	Y1213	A1216S	1216	Missense	distal	3	no	5.316	5.089	EPSD;PhosphoSitePlus	COSMIC	1.801	Down-regulation
TK_VEGFR_FLT1_Y	P17948	FLT1	P17948	FLT1	Y1213	F1219Y	1219	Missense	distal	6	no	5.316	5.203	EPSD;PhosphoSitePlus	COSMIC	1.801	Down-regulation
TK_VEGFR_FLT1_Y	P17948	FLT1	P17948	FLT1	Y1213	D1209N	1209	Missense	distal	-4	no	5.316	5.320	EPSD;PhosphoSitePlus	COSMIC	1.801	Up-regulation
TK_VEGFR_FLT1_Y	P17948	FLT1	P17948	FLT1	Y1213	V1214A	1214	Missense	proximal	1	no	5.316	5.301	EPSD;PhosphoSitePlus	COSMIC;GDSC;CCLE	1.801	Down-regulation
TK_VEGFR_FLT1_Y	P17948	FLT1	P17948	FLT1	Y1242	L1249M	1249	Missense	distal	7	no	5.055	5.007	EPSD;PhosphoSitePlus	COSMIC	1.801	Down-regulation
TK_VEGFR_FLT1_Y	P17948	FLT1	P17948	FLT1	Y1242	D1240H	1240	Missense	proximal	-2	no	5.055	4.906	EPSD;PhosphoSitePlus	COSMIC	1.801	Down-regulation
TK_VEGFR_FLT1_Y	P17948	FLT1	P17948	FLT1	Y1242	Q1243K	1243	Missense	proximal	1	no	5.055	5.064	EPSD;PhosphoSitePlus	COSMIC;GDSC;CCLE	1.801	Up-regulation
TK_VEGFR_FLT1_Y	P17948	FLT1	P17948	FLT1	Y1242	S1237F	1237	Missense	distal	-5	no	5.055	4.374	EPSD;PhosphoSitePlus	COSMIC	1.801	Down-regulation
TK_VEGFR_FLT1_Y	P17948	FLT1	P17948	FLT1	Y1309	R1305C	1305	Missense	distal	-4	no	4.757	4.756	EPSD	COSMIC	1.801	Down-regulation
TK_VEGFR_FLT1_Y	P17948	FLT1	P17948	FLT1	Y1309	A1312T	1312	Missense	distal	3	no	4.757	4.363	EPSD	COSMIC;GDSC;CCLE	1.801	Down-regulation
TK_VEGFR_FLT1_Y	P17948	FLT1	P17948	FLT1	Y1309	E1302K	1302	Missense	distal	-7	no	4.757	4.796	EPSD	COSMIC	1.801	Up-regulation
TK_VEGFR_FLT1_Y	P17948	FLT1	P17948	FLT1	Y1309	A1312V	1312	Missense	distal	3	no	4.757	4.512	EPSD	COSMIC	1.801	Down-regulation
Other_WNK_WNK3_ST	Q9H4A3	WNK1	Q9BYP7	WNK3	S170	S167F	167	Missense	distal	-3	no	2.460	2.495	EPSD	COSMIC	2.233	Up-regulation
Other_WNK_WNK3_ST	Q9H4A3	WNK1	Q9BYP7	WNK3	T209	L207P	207	Missense	proximal	-2	no	2.846	2.285	EPSD	COSMIC	2.233	Down-regulation
Other_WNK_WNK3_ST	Q9H4A3	WNK1	Q9BYP7	WNK3	T373	S378P	378	Missense	distal	5	no	2.073	2.248	EPSD	COSMIC	2.233	Gain
Other_WNK_WNK3_ST	Q9H4A3	WNK1	Q9BYP7	WNK3	T436	S437R	437	Missense	proximal	1	no	2.350	2.339	EPSD	COSMIC	2.233	Down-regulation
Other_WNK_WNK3_ST	Q9H4A3	WNK1	Q9BYP7	WNK3	T436	S443T	443	Missense	distal	7	no	2.350	2.275	EPSD	COSMIC	2.233	Down-regulation
Other_WNK_WNK3_ST	Q9H4A3	WNK1	Q9BYP7	WNK3	T436	V439A	439	Missense	distal	3	no	2.350	2.134	EPSD	COSMIC	2.233	Loss
Other_WNK_WNK3_ST	Q9H4A3	WNK1	Q9BYP7	WNK3	T436	A429V	429	Missense	distal	-7	no	2.350	2.366	EPSD	COSMIC	2.233	Up-regulation
Other_WNK_WNK3_ST	Q9H4A3	WNK1	Q9BYP7	WNK3	S597	I603T	603	Missense	distal	6	no	3.602	3.315	EPSD	COSMIC	2.233	Down-regulation
Other_WNK_WNK3_ST	Q9H4A3	WNK1	Q9BYP7	WNK3	S1289	A1287S	1287	Missense	proximal	-2	no	2.660	2.322	EPSD	COSMIC	2.233	Down-regulation
Other_WNK_WNK3_ST	Q9H4A3	WNK1	Q9BYP7	WNK3	S1289	A1284E	1284	Missense	distal	-5	no	2.660	2.790	EPSD	COSMIC	2.233	Up-regulation
Other_WNK_WNK3_ST	Q9H4A3	WNK1	Q9BYP7	WNK3	S1289	A1283D	1283	Missense	distal	-6	no	2.660	2.708	EPSD	COSMIC	2.233	Up-regulation
Other_WNK_WNK3_ST	Q9H4A3	WNK1	Q9BYP7	WNK3	S1289	H1296Y	1296	Missense	distal	7	no	2.660	2.842	EPSD	COSMIC;CCLE	2.233	Up-regulation
Other_WNK_WNK3_ST	Q9H4A3	WNK1	Q9BYP7	WNK3	S1289	A1284T	1284	Missense	distal	-5	no	2.660	2.873	EPSD	COSMIC	2.233	Up-regulation
Other_WNK_WNK3_ST	Q9H4A3	WNK1	Q9BYP7	WNK3	T1913	P1915H	1915	Missense	proximal	2	no	2.817	2.780	EPSD	COSMIC	2.233	Down-regulation
Other_WNK_WNK3_ST	Q9H4A3	WNK1	Q9BYP7	WNK3	T1913	K1906I	1906	Missense	distal	-7	no	2.817	2.972	EPSD	COSMIC	2.233	Up-regulation
Other_WNK_WNK3_ST	Q9H4A3	WNK1	Q9BYP7	WNK3	T1913	P1915S	1915	Missense	proximal	2	no	2.817	2.734	EPSD	COSMIC	2.233	Down-regulation
Other_WNK_WNK3_ST	Q9H4A3	WNK1	Q9BYP7	WNK3	T1913	P1915A	1915	Missense	proximal	2	no	2.817	2.700	EPSD	COSMIC	2.233	Down-regulation
Other_WNK_WNK3_ST	Q9H4A3	WNK1	Q9BYP7	WNK3	T1928	P1922H	1922	Missense	distal	-6	no	2.931	3.231	EPSD	COSMIC	2.233	Up-regulation
Other_WNK_WNK3_ST	Q9H4A3	WNK1	Q9BYP7	WNK3	T1928	A1933T	1933	Missense	distal	5	no	2.931	2.982	EPSD	COSMIC	2.233	Up-regulation
Other_WNK_WNK3_ST	Q9H4A3	WNK1	Q9BYP7	WNK3	T1937	Q1939K	1939	Missense	proximal	2	no	2.343	2.266	EPSD	COSMIC	2.233	Down-regulation
Other_WNK_WNK3_ST	Q9H4A3	WNK1	Q9BYP7	WNK3	T1970	D1969G	1969	Missense	proximal	-1	no	2.745	2.399	EPSD	COSMIC	2.233	Down-regulation
Other_WNK_WNK3_ST	Q9H4A3	WNK1	Q9BYP7	WNK3	S2005	P2004R	2004	Missense	proximal	-1	no	2.115	2.242	EPSD	COSMIC	2.233	Gain
Other_WNK_WNK3_ST	Q9H4A3	WNK1	Q9BYP7	WNK3	T2245	D2249N	2249	Missense	distal	4	no	3.613	3.516	EPSD	COSMIC	2.233	Down-regulation
Other_WNK_WNK3_ST	Q9H4A3	WNK1	Q9BYP7	WNK3	T2245	D2248H	2248	Missense	distal	3	no	3.613	3.561	EPSD	COSMIC	2.233	Down-regulation
Other_WNK_WNK3_ST	Q9H4A3	WNK1	Q9BYP7	WNK3	S2370	G2376D	2376	Missense	distal	6	no	2.286	2.185	EPSD	COSMIC	2.233	Loss
Other_WNK_WNK3_ST	Q9H4A3	WNK1	Q9BYP7	WNK3	S2370	S2377T	2377	Missense	distal	7	no	2.286	2.211	EPSD	COSMIC	2.233	Loss
Other_WNK_WNK3_ST	Q9UHW9	SLC12A6	Q9BYP7	WNK3	S96	I97V	97	Missense	proximal	1	no	6.778	6.861	EPSD;PhosphoSitePlus	COSMIC	2.233	Up-regulation
Other_WNK_WNK3_ST	Q9UHW9	SLC12A6	Q9BYP7	WNK3	S96	G99W	99	Missense	distal	3	no	6.778	6.626	EPSD;PhosphoSitePlus	COSMIC	2.233	Down-regulation
Other_WNK_WNK3_ST	Q9UHW9	SLC12A6	Q9BYP7	WNK3	S96	G99A	99	Missense	distal	3	no	6.778	6.684	EPSD;PhosphoSitePlus	COSMIC	2.233	Down-regulation
Other_WNK_WNK3_ST	Q9UHW9	SLC12A6	Q9BYP7	WNK3	S120	E123K	123	Missense	distal	3	no	3.253	3.559	EPSD	COSMIC	2.233	Up-regulation
Other_WNK_WNK3_ST	Q9UHW9	SLC12A6	Q9BYP7	WNK3	S120	D126N	126	Missense	distal	6	no	3.253	3.307	EPSD	COSMIC	2.233	Up-regulation
Other_WNK_WNK3_ST	Q9UHW9	SLC12A6	Q9BYP7	WNK3	S120	N119K	119	Missense	proximal	-1	no	3.253	3.135	EPSD	COSMIC	2.233	Down-regulation
Other_WNK_WNK3_ST	Q9UHW9	SLC12A6	Q9BYP7	WNK3	S148	R152S	152	Missense	distal	4	no	2.255	2.370	EPSD	COSMIC	2.233	Up-regulation
Other_WNK_WNK3_ST	Q9UHW9	SLC12A6	Q9BYP7	WNK3	S148	R152H	152	Missense	distal	4	no	2.255	2.431	EPSD	COSMIC	2.233	Up-regulation
Other_WNK_WNK3_ST	Q9UHW9	SLC12A6	Q9BYP7	WNK3	S148	D141N	141	Missense	distal	-7	no	2.255	2.199	EPSD	COSMIC	2.233	Loss
Other_WNK_WNK3_ST	Q9UHW9	SLC12A6	Q9BYP7	WNK3	S148	R152L	152	Missense	distal	4	no	2.255	2.346	EPSD	COSMIC	2.233	Up-regulation
Other_WNK_WNK3_ST	Q9UHW9	SLC12A6	Q9BYP7	WNK3	S148	L149I	149	Missense	proximal	1	no	2.255	2.220	EPSD	COSMIC	2.233	Loss
Other_WNK_WNK3_ST	Q9UHW9	SLC12A6	Q9BYP7	WNK3	S148	R143S	143	Missense	distal	-5	no	2.255	2.352	EPSD	COSMIC	2.233	Up-regulation
Other_WNK_WNK3_ST	Q9UHW9	SLC12A6	Q9BYP7	WNK3	S148	R143C	143	Missense	distal	-5	no	2.255	2.320	EPSD	COSMIC	2.233	Up-regulation
Other_WNK_WNK3_ST	Q9UHW9	SLC12A6	Q9BYP7	WNK3	S148	R143H	143	Missense	distal	-5	no	2.255	2.412	EPSD	COSMIC	2.233	Up-regulation
Other_WNK_WNK3_ST	Q9UHW9	SLC12A6	Q9BYP7	WNK3	S148	R143L	143	Missense	distal	-5	no	2.255	2.338	EPSD	COSMIC	2.233	Up-regulation
Other_WNK_WNK3_ST	Q9UHW9	SLC12A6	Q9BYP7	WNK3	T182	M189I	189	Missense	distal	7	no	2.371	2.499	EPSD	COSMIC	2.233	Up-regulation
Other_WNK_WNK3_ST	Q9UHW9	SLC12A6	Q9BYP7	WNK3	T182	P179H	179	Missense	distal	-3	no	2.371	2.427	EPSD	COSMIC	2.233	Up-regulation
Other_WNK_WNK3_ST	Q9UHW9	SLC12A6	Q9BYP7	WNK3	T182	P183L	183	Missense	proximal	1	no	2.371	2.684	EPSD	COSMIC	2.233	Up-regulation
Other_WNK_WNK3_ST	Q9UHW9	SLC12A6	Q9BYP7	WNK3	T182	T180I	180	Missense	proximal	-2	no	2.371	1.931	EPSD	COSMIC	2.233	Loss
Other_WNK_WNK3_ST	Q9UHW9	SLC12A6	Q9BYP7	WNK3	T991	R990Q	990	Missense	proximal	-1	no	7.155	7.167	EPSD;PhosphoSitePlus	COSMIC	2.233	Up-regulation
Other_WNK_WNK3_ST	Q9UHW9	SLC12A6	Q9BYP7	WNK3	T991	R990W	990	Missense	proximal	-1	no	7.155	7.033	EPSD;PhosphoSitePlus	COSMIC	2.233	Down-regulation
Other_WNK_WNK3_ST	Q9UHW9	SLC12A6	Q9BYP7	WNK3	T991	R997M	997	Missense	distal	6	no	7.155	7.162	EPSD;PhosphoSitePlus	COSMIC	2.233	Up-regulation
Other_WNK_WNK3_ST	Q9UHW9	SLC12A6	Q9BYP7	WNK3	T991	R990C	990	Missense	proximal	-1	no	7.155	7.039	EPSD;PhosphoSitePlus	COSMIC	2.233	Down-regulation
Other_WNK_WNK3_ST	Q9UHW9	SLC12A6	Q9BYP7	WNK3	T1028	R1026Q	1026	Missense	proximal	-2	no	2.932	3.424	EPSD	COSMIC	2.233	Up-regulation
Other_WNK_WNK3_ST	Q9UHW9	SLC12A6	Q9BYP7	WNK3	T1028	D1033N	1033	Missense	distal	5	no	2.932	3.039	EPSD	COSMIC	2.233	Up-regulation
Other_WNK_WNK3_ST	Q9UHW9	SLC12A6	Q9BYP7	WNK3	T1028	R1026L	1026	Missense	proximal	-2	no	2.932	3.414	EPSD	COSMIC	2.233	Up-regulation
Other_WNK_WNK3_ST	Q9UHW9	SLC12A6	Q9BYP7	WNK3	T1038	D1033N	1033	Missense	distal	-5	no	2.422	2.368	EPSD	COSMIC	2.233	Down-regulation
Other_WNK_WNK3_ST	Q9UHW9	SLC12A6	Q9BYP7	WNK3	T1040	D1033N	1033	Missense	distal	-7	no	2.239	2.183	EPSD	COSMIC	2.233	Loss
Other_WNK_WNK3_ST	Q9UHW9	SLC12A6	Q9BYP7	WNK3	T1129	E1126D	1126	Missense	distal	-3	no	2.438	2.403	EPSD	COSMIC	2.233	Down-regulation
Other_WNK_WNK3_ST	Q9UHW9	SLC12A6	Q9BYP7	WNK3	T1129	L1125P	1125	Missense	distal	-4	no	2.438	2.437	EPSD	COSMIC	2.233	Down-regulation
Other_WNK_WNK3_ST	Q9UHW9	SLC12A6	Q9BYP7	WNK3	T1129	L1132Q	1132	Missense	distal	3	no	2.438	2.558	EPSD	COSMIC	2.233	Up-regulation
TKL_RIPK_RIPK2_ST	O43353	RIPK2	O43353	RIPK2	S174	S181N	181	Missense	distal	7	no	7.284	6.471	PhosphoSitePlus;EPSD	COSMIC	3.253	Down-regulation
TKL_RIPK_RIPK2_ST	O43353	RIPK2	O43353	RIPK2	S176	S181N	181	Missense	distal	5	no	7.813	7.298	EPSD;PhosphoSitePlus	COSMIC	3.253	Down-regulation
TKL_RIPK_RIPK2_ST	O43353	RIPK2	O43353	RIPK2	S178	S181N	181	Missense	distal	3	no	8.332	7.834	EPSD;PhosphoSitePlus	COSMIC	3.253	Down-regulation
TKL_RIPK_RIPK2_ST	O43353	RIPK2	O43353	RIPK2	S180	S181N	181	Missense	proximal	1	no	6.922	6.732	EPSD;PhosphoSitePlus	COSMIC	3.253	Down-regulation
TKL_RIPK_RIPK2_ST	O43353	RIPK2	O43353	RIPK2	S180	E186K	186	Missense	distal	6	no	6.922	6.962	EPSD;PhosphoSitePlus	COSMIC;GDSC;CCLE	3.253	Up-regulation
TKL_RIPK_RIPK2_ST	O43353	RIPK2	O43353	RIPK2	S181	S181N	181	Missense	central	0	yes	7.197	0.000	EPSD;PhosphoSitePlus	COSMIC	3.253	Loss
TKL_RIPK_RIPK2_ST	O43353	RIPK2	O43353	RIPK2	S181	E186K	186	Missense	distal	5	no	7.197	7.402	EPSD;PhosphoSitePlus	COSMIC;GDSC;CCLE	3.253	Up-regulation
TKL_RIPK_RIPK2_ST	O43353	RIPK2	O43353	RIPK2	S183	E186K	186	Missense	distal	3	no	3.050	3.297	EPSD	COSMIC;GDSC;CCLE	3.253	Gain
TKL_RIPK_RIPK2_ST	O43353	RIPK2	O43353	RIPK2	S355	S348F	348	Missense	distal	-7	no	3.770	3.541	EPSD	COSMIC	3.253	Down-regulation
TKL_RIPK_RIPK2_ST	O43353	RIPK2	O43353	RIPK2	S355	Q350H	350	Missense	distal	-5	no	3.770	3.766	EPSD	COSMIC	3.253	Down-regulation
TKL_RIPK_RIPK2_ST	O43353	RIPK2	O43353	RIPK2	S355	P358A	358	Missense	distal	3	no	3.770	3.716	EPSD	COSMIC	3.253	Down-regulation
TKL_RIPK_RIPK2_ST	O43353	RIPK2	O43353	RIPK2	S355	Q350E	350	Missense	distal	-5	no	3.770	3.765	EPSD	COSMIC	3.253	Down-regulation
TKL_RIPK_RIPK2_ST	O43353	RIPK2	O43353	RIPK2	S355	G356C	356	Missense	proximal	1	no	3.770	3.732	EPSD	COSMIC;CCLE	3.253	Down-regulation
TKL_RIPK_RIPK2_ST	O43353	RIPK2	O43353	RIPK2	S361	P358A	358	Missense	distal	-3	no	3.262	3.264	EPSD	COSMIC	3.253	Up-regulation
TKL_RIPK_RIPK2_ST	O43353	RIPK2	O43353	RIPK2	S361	G356C	356	Missense	distal	-5	no	3.262	3.254	EPSD	COSMIC;CCLE	3.253	Down-regulation
TKL_RIPK_RIPK2_ST	O43353	RIPK2	O43353	RIPK2	S399	S393N	393	Missense	distal	-6	no	3.451	3.384	EPSD	COSMIC	3.253	Down-regulation
TKL_RIPK_RIPK2_ST	O43353	RIPK2	O43353	RIPK2	S399	H392Y	392	Missense	distal	-7	no	3.451	3.434	EPSD	COSMIC	3.253	Down-regulation
TKL_RIPK_RIPK2_ST	O43353	RIPK2	O43353	RIPK2	S527	P530S	530	Missense	distal	3	no	2.937	3.307	EPSD	COSMIC;CCLE	3.253	Gain
TKL_RIPK_RIPK2_ST	O43353	RIPK2	O43353	RIPK2	S529	P530S	530	Missense	proximal	1	no	3.905	4.082	EPSD	COSMIC;CCLE	3.253	Up-regulation
TKL_RIPK_RIPK2_ST	O43353	RIPK2	O43353	RIPK2	S529	S527C	527	Missense	proximal	-2	no	3.905	2.744	EPSD	COSMIC	3.253	Loss
TKL_RIPK_RIPK2_ST	O43353	RIPK2	O43353	RIPK2	S529	I523M	523	Missense	distal	-6	no	3.905	3.954	EPSD	COSMIC	3.253	Up-regulation
TK_InsR_IGF1R_Y	P35568	IRS1	P08069	IGF1R	Y47	G40V	40	Missense	distal	-7	no	3.370	3.335	EPSD	COSMIC	3.025	Down-regulation
TK_InsR_IGF1R_Y	P35568	IRS1	P08069	IGF1R	Y47	Y47C	47	Missense	central	0	yes	3.370	0.000	EPSD	COSMIC	3.025	Loss
TK_InsR_IGF1R_Y	P35568	IRS1	P08069	IGF1R	Y431	P435L	435	Missense	distal	4	no	4.578	4.039	EPSD	COSMIC	3.025	Down-regulation
TK_InsR_IGF1R_Y	P35568	IRS1	P08069	IGF1R	Y431	S434G	434	Missense	distal	3	no	4.578	4.489	EPSD	COSMIC	3.025	Down-regulation
TK_InsR_IGF1R_Y	P35568	IRS1	P08069	IGF1R	Y431	G424C	424	Missense	distal	-7	no	4.578	4.815	EPSD	COSMIC	3.025	Up-regulation
TK_InsR_IGF1R_Y	P35568	IRS1	P08069	IGF1R	Y431	P435F	435	Missense	distal	4	no	4.578	3.955	EPSD	COSMIC	3.025	Down-regulation
TK_InsR_IGF1R_Y	P35568	IRS1	P08069	IGF1R	Y612	P614A	614	Missense	proximal	2	no	5.097	4.789	EPSD	COSMIC;CCLE	3.025	Down-regulation
TK_InsR_IGF1R_Y	P35568	IRS1	P08069	IGF1R	Y632	G628D	628	Missense	distal	-4	no	7.153	7.156	EPSD;PhosphoSitePlus	COSMIC	3.025	Up-regulation
TK_InsR_IGF1R_Y	P35568	IRS1	P08069	IGF1R	Y632	R626Q	626	Missense	distal	-6	no	7.153	7.087	EPSD;PhosphoSitePlus	COSMIC	3.025	Down-regulation
TK_InsR_IGF1R_Y	P35568	IRS1	P08069	IGF1R	Y632	G630E	630	Missense	proximal	-2	no	7.153	7.254	EPSD;PhosphoSitePlus	COSMIC	3.025	Up-regulation
TK_InsR_IGF1R_Y	P35568	IRS1	P08069	IGF1R	Y662	G661D	661	Missense	proximal	-1	no	5.753	5.799	EPSD;PhosphoSitePlus	COSMIC	3.025	Up-regulation
TK_InsR_IGF1R_Y	P35568	IRS1	P08069	IGF1R	Y662	G669S	669	Missense	distal	7	no	5.753	5.697	EPSD;PhosphoSitePlus	COSMIC	3.025	Down-regulation
TK_InsR_IGF1R_Y	P35568	IRS1	P08069	IGF1R	Y662	M664I	664	Missense	proximal	2	no	5.753	4.911	EPSD;PhosphoSitePlus	COSMIC	3.025	Down-regulation
TK_InsR_IGF1R_Y	P35568	IRS1	P08069	IGF1R	Y662	V657L	657	Missense	distal	-5	no	5.753	5.827	EPSD;PhosphoSitePlus	COSMIC	3.025	Up-regulation
TK_InsR_IGF1R_Y	P35568	IRS1	P08069	IGF1R	Y662	Q655H	655	Missense	distal	-7	no	5.753	5.923	EPSD;PhosphoSitePlus	COSMIC;GDSC;CCLE	3.025	Up-regulation
TK_InsR_IGF1R_Y	P35568	IRS1	P08069	IGF1R	Y732	D731G	731	Missense	proximal	-1	no	3.821	3.776	EPSD;PhosphoSitePlus	COSMIC	3.025	Down-regulation
TK_InsR_IGF1R_Y	P35568	IRS1	P08069	IGF1R	Y732	V738G	738	Missense	distal	6	no	3.821	3.781	EPSD;PhosphoSitePlus	COSMIC	3.025	Down-regulation
TK_InsR_IGF1R_Y	P35568	IRS1	P08069	IGF1R	Y732	G739E	739	Missense	distal	7	no	3.821	3.778	EPSD;PhosphoSitePlus	COSMIC	3.025	Down-regulation
TK_InsR_IGF1R_Y	P35568	IRS1	P08069	IGF1R	Y732	N734I	734	Missense	proximal	2	no	3.821	1.958	EPSD;PhosphoSitePlus	COSMIC	3.025	Loss
TK_InsR_IGF1R_Y	P35568	IRS1	P08069	IGF1R	Y732	N734K	734	Missense	proximal	2	no	3.821	2.853	EPSD;PhosphoSitePlus	COSMIC	3.025	Loss
TK_InsR_IGF1R_Y	P35568	IRS1	P08069	IGF1R	Y750	P753L	753	Missense	distal	3	no	2.968	3.360	EPSD	COSMIC	3.025	Gain
TK_InsR_IGF1R_Y	P35568	IRS1	P08069	IGF1R	Y764	S763A	763	Missense	proximal	-1	no	3.961	3.768	EPSD	COSMIC	3.025	Down-regulation
TK_InsR_IGF1R_Y	P35568	IRS1	P08069	IGF1R	Y764	Q757K	757	Missense	distal	-7	no	3.961	3.994	EPSD	COSMIC	3.025	Up-regulation
TK_InsR_IGF1R_Y	P35568	IRS1	P08069	IGF1R	Y764	S766T	766	Missense	proximal	2	no	3.961	3.123	EPSD	COSMIC	3.025	Down-regulation
TK_InsR_IGF1R_Y	P35568	IRS1	P08069	IGF1R	Y941	K943Q	943	Missense	proximal	2	no	5.533	5.721	EPSD;PhosphoSitePlus	COSMIC	3.025	Up-regulation
TK_InsR_IGF1R_Y	P35568	IRS1	P08069	IGF1R	Y941	T936I	936	Missense	distal	-5	no	5.533	5.714	EPSD;PhosphoSitePlus	COSMIC	3.025	Up-regulation
TK_InsR_IGF1R_Y	P35568	IRS1	P08069	IGF1R	Y941	L946P	946	Missense	distal	5	no	5.533	5.656	EPSD;PhosphoSitePlus	COSMIC	3.025	Up-regulation
TK_InsR_IGF1R_Y	P35568	IRS1	P08069	IGF1R	Y989	P983S	983	Missense	distal	-6	no	7.413	7.403	PhosphoSitePlus;EPSD	COSMIC	3.025	Down-regulation
TK_InsR_IGF1R_Y	P35568	IRS1	P08069	IGF1R	Y989	S985N	985	Missense	distal	-4	no	7.413	7.393	PhosphoSitePlus;EPSD	COSMIC	3.025	Down-regulation
TK_InsR_IGF1R_Y	P35568	IRS1	P08069	IGF1R	Y989	M992K	992	Missense	distal	3	no	7.413	6.948	PhosphoSitePlus;EPSD	COSMIC	3.025	Down-regulation
TK_InsR_IGF1R_Y	P35568	IRS1	P08069	IGF1R	Y1001	R998C	998	Missense	distal	-3	no	3.560	3.326	EPSD	COSMIC;GDSC;CCLE	3.025	Down-regulation
TK_InsR_IGF1R_Y	P35568	IRS1	P08069	IGF1R	Y1001	D1003H	1003	Missense	proximal	2	no	3.560	3.378	EPSD	COSMIC	3.025	Down-regulation
TK_InsR_IGF1R_Y	P35568	IRS1	P08069	IGF1R	Y1001	P997S	997	Missense	distal	-4	no	3.560	3.585	EPSD	COSMIC	3.025	Up-regulation
TK_InsR_IGF1R_Y	P35568	IRS1	P08069	IGF1R	Y1179	G1172D	1172	Missense	distal	-7	no	3.926	4.033	EPSD;PhosphoSitePlus	COSMIC	3.025	Up-regulation
TK_InsR_IGF1R_Y	P35568	IRS1	P08069	IGF1R	Y1179	K1186N	1186	Missense	distal	7	no	3.926	3.900	EPSD;PhosphoSitePlus	COSMIC;GDSC;CCLE	3.025	Down-regulation
TK_InsR_IGF1R_Y	P35568	IRS1	P08069	IGF1R	Y1179	D1181E	1181	Missense	proximal	2	no	3.926	4.027	EPSD;PhosphoSitePlus	COSMIC	3.025	Up-regulation
TK_InsR_IGF1R_Y	P35568	IRS1	P08069	IGF1R	Y1179	D1181H	1181	Missense	proximal	2	no	3.926	3.745	EPSD;PhosphoSitePlus	COSMIC;GDSC;CCLE	3.025	Down-regulation
TK_InsR_IGF1R_Y	P08069	IGF1R	P08069	IGF1R	Y973	R966S	966	Missense	distal	-7	no	5.707	5.217	EPSD	COSMIC	3.025	Down-regulation
TK_InsR_IGF1R_Y	P08069	IGF1R	P08069	IGF1R	Y973	G970E	970	Missense	distal	-3	no	5.707	6.132	EPSD	COSMIC	3.025	Up-regulation
TK_InsR_IGF1R_Y	P08069	IGF1R	P08069	IGF1R	Y973	E979K	979	Missense	distal	6	no	5.707	5.678	EPSD	COSMIC	3.025	Down-regulation
TK_InsR_IGF1R_Y	P08069	IGF1R	P08069	IGF1R	Y973	V976E	976	Missense	distal	3	no	5.707	5.453	EPSD	COSMIC	3.025	Down-regulation
TK_InsR_IGF1R_Y	P08069	IGF1R	P08069	IGF1R	Y973	E979Q	979	Missense	distal	6	no	5.707	5.700	EPSD	COSMIC	3.025	Down-regulation
TK_InsR_IGF1R_Y	P08069	IGF1R	P08069	IGF1R	Y973	G968R	968	Missense	distal	-5	no	5.707	5.664	EPSD	COSMIC	3.025	Down-regulation
TK_InsR_IGF1R_Y	P08069	IGF1R	P08069	IGF1R	Y973	V976L	976	Missense	distal	3	no	5.707	5.667	EPSD	COSMIC	3.025	Down-regulation
TK_InsR_IGF1R_Y	P08069	IGF1R	P08069	IGF1R	Y973	V976M	976	Missense	distal	3	no	5.707	6.091	EPSD	COSMIC	3.025	Up-regulation
TK_InsR_IGF1R_Y	P08069	IGF1R	P08069	IGF1R	Y980	E979K	979	Missense	proximal	-1	no	5.088	5.112	PhosphoSitePlus;EPSD	COSMIC	3.025	Up-regulation
TK_InsR_IGF1R_Y	P08069	IGF1R	P08069	IGF1R	Y980	V976E	976	Missense	distal	-4	no	5.088	5.103	PhosphoSitePlus;EPSD	COSMIC	3.025	Up-regulation
TK_InsR_IGF1R_Y	P08069	IGF1R	P08069	IGF1R	Y980	E979Q	979	Missense	proximal	-1	no	5.088	5.114	PhosphoSitePlus;EPSD	COSMIC	3.025	Up-regulation
TK_InsR_IGF1R_Y	P08069	IGF1R	P08069	IGF1R	Y980	V976L	976	Missense	distal	-4	no	5.088	5.053	PhosphoSitePlus;EPSD	COSMIC	3.025	Down-regulation
TK_InsR_IGF1R_Y	P08069	IGF1R	P08069	IGF1R	Y980	V976M	976	Missense	distal	-4	no	5.088	5.091	PhosphoSitePlus;EPSD	COSMIC	3.025	Up-regulation
TK_InsR_IGF1R_Y	P08069	IGF1R	P08069	IGF1R	Y1161	T1163A	1163	Missense	proximal	2	no	3.599	3.543	EPSD;PhosphoSitePlus	COSMIC	3.025	Down-regulation
TK_InsR_IGF1R_Y	P08069	IGF1R	P08069	IGF1R	Y1161	R1167W	1167	Missense	distal	6	no	3.599	3.585	EPSD;PhosphoSitePlus	COSMIC	3.025	Down-regulation
TK_InsR_IGF1R_Y	P08069	IGF1R	P08069	IGF1R	Y1161	T1157A	1157	Missense	distal	-4	no	3.599	3.590	EPSD;PhosphoSitePlus	COSMIC	3.025	Down-regulation
TK_InsR_IGF1R_Y	P08069	IGF1R	P08069	IGF1R	Y1161	E1162Q	1162	Missense	proximal	1	no	3.599	3.687	EPSD;PhosphoSitePlus	COSMIC	3.025	Up-regulation
TK_InsR_IGF1R_Y	P08069	IGF1R	P08069	IGF1R	Y1161	F1154L	1154	Missense	distal	-7	no	3.599	3.469	EPSD;PhosphoSitePlus	COSMIC	3.025	Down-regulation
TK_InsR_IGF1R_Y	P08069	IGF1R	P08069	IGF1R	Y1161	G1155D	1155	Missense	distal	-6	no	3.599	3.688	EPSD;PhosphoSitePlus	COSMIC	3.025	Up-regulation
TK_InsR_IGF1R_Y	P08069	IGF1R	P08069	IGF1R	Y1165	T1163A	1163	Missense	proximal	-2	no	5.207	5.166	EPSD;PhosphoSitePlus	COSMIC	3.025	Down-regulation
TK_InsR_IGF1R_Y	P08069	IGF1R	P08069	IGF1R	Y1165	R1167W	1167	Missense	proximal	2	no	5.207	4.341	EPSD;PhosphoSitePlus	COSMIC	3.025	Down-regulation
TK_InsR_IGF1R_Y	P08069	IGF1R	P08069	IGF1R	Y1165	E1162Q	1162	Missense	distal	-3	no	5.207	4.975	EPSD;PhosphoSitePlus	COSMIC	3.025	Down-regulation
TK_InsR_IGF1R_Y	P08069	IGF1R	P08069	IGF1R	Y1166	T1163A	1163	Missense	distal	-3	no	5.167	5.055	EPSD;PhosphoSitePlus	COSMIC	3.025	Down-regulation
TK_InsR_IGF1R_Y	P08069	IGF1R	P08069	IGF1R	Y1166	R1167W	1167	Missense	proximal	1	no	5.167	5.000	EPSD;PhosphoSitePlus	COSMIC	3.025	Down-regulation
TK_InsR_IGF1R_Y	P08069	IGF1R	P08069	IGF1R	Y1166	E1162Q	1162	Missense	distal	-4	no	5.167	5.173	EPSD;PhosphoSitePlus	COSMIC	3.025	Up-regulation
TK_InsR_IGF1R_Y	P08069	IGF1R	P08069	IGF1R	Y1280	R1275Q	1275	Missense	distal	-5	no	5.024	4.974	EPSD;PhosphoSitePlus	COSMIC	3.025	Down-regulation
TK_InsR_IGF1R_Y	P08069	IGF1R	P08069	IGF1R	Y1280	S1282I	1282	Missense	proximal	2	no	5.024	2.840	EPSD;PhosphoSitePlus	COSMIC	3.025	Loss
TK_InsR_IGF1R_Y	P08069	IGF1R	P08069	IGF1R	Y1280	E1284K	1284	Missense	distal	4	no	5.024	5.012	EPSD;PhosphoSitePlus	COSMIC	3.025	Down-regulation
TK_InsR_IGF1R_Y	P08069	IGF1R	P08069	IGF1R	Y1280	S1282R	1282	Missense	proximal	2	no	5.024	3.840	EPSD;PhosphoSitePlus	COSMIC	3.025	Down-regulation
TK_InsR_IGF1R_Y	P08069	IGF1R	P08069	IGF1R	Y1280	R1275W	1275	Missense	distal	-5	no	5.024	5.148	EPSD;PhosphoSitePlus	COSMIC	3.025	Up-regulation
TK_InsR_IGF1R_Y	P08069	IGF1R	P08069	IGF1R	Y1280	E1276D	1276	Missense	distal	-4	no	5.024	5.018	EPSD;PhosphoSitePlus	COSMIC	3.025	Down-regulation
TK_InsR_IGF1R_Y	P08069	IGF1R	P08069	IGF1R	Y1280	E1283K	1283	Missense	distal	3	no	5.024	5.198	EPSD;PhosphoSitePlus	COSMIC	3.025	Up-regulation
TK_InsR_IGF1R_Y	P08069	IGF1R	P08069	IGF1R	Y1281	R1275Q	1275	Missense	distal	-6	no	3.503	3.438	EPSD;PhosphoSitePlus	COSMIC	3.025	Down-regulation
TK_InsR_IGF1R_Y	P08069	IGF1R	P08069	IGF1R	Y1281	S1282I	1282	Missense	proximal	1	no	3.503	3.273	EPSD;PhosphoSitePlus	COSMIC	3.025	Down-regulation
TK_InsR_IGF1R_Y	P08069	IGF1R	P08069	IGF1R	Y1281	P1288L	1288	Missense	distal	7	no	3.503	3.548	EPSD;PhosphoSitePlus	COSMIC	3.025	Up-regulation
TK_InsR_IGF1R_Y	P08069	IGF1R	P08069	IGF1R	Y1281	E1284K	1284	Missense	distal	3	no	3.503	3.677	EPSD;PhosphoSitePlus	COSMIC	3.025	Up-regulation
TK_InsR_IGF1R_Y	P08069	IGF1R	P08069	IGF1R	Y1281	S1282R	1282	Missense	proximal	1	no	3.503	3.173	EPSD;PhosphoSitePlus	COSMIC	3.025	Down-regulation
TK_InsR_IGF1R_Y	P08069	IGF1R	P08069	IGF1R	Y1281	R1275W	1275	Missense	distal	-6	no	3.503	3.529	EPSD;PhosphoSitePlus	COSMIC	3.025	Up-regulation
TK_InsR_IGF1R_Y	P08069	IGF1R	P08069	IGF1R	Y1281	E1276D	1276	Missense	distal	-5	no	3.503	3.549	EPSD;PhosphoSitePlus	COSMIC	3.025	Up-regulation
TK_InsR_IGF1R_Y	P08069	IGF1R	P08069	IGF1R	Y1281	E1283K	1283	Missense	proximal	2	no	3.503	3.274	EPSD;PhosphoSitePlus	COSMIC	3.025	Down-regulation
TK_InsR_IGF1R_Y	P08069	IGF1R	P08069	IGF1R	Y1346	A1347V	1347	Missense	proximal	1	no	4.650	4.409	EPSD	COSMIC	3.025	Down-regulation
TK_InsR_IGF1R_Y	P08069	IGF1R	P08069	IGF1R	Y1346	R1353C	1353	Missense	distal	7	no	4.650	4.658	EPSD	COSMIC	3.025	Up-regulation
TK_InsR_IGF1R_Y	P08069	IGF1R	P08069	IGF1R	Y1346	S1339C	1339	Missense	distal	-7	no	4.650	5.263	EPSD	COSMIC	3.025	Up-regulation
TK_InsR_IGF1R_Y	P08069	IGF1R	P08069	IGF1R	Y1346	D1341N	1341	Missense	distal	-5	no	4.650	4.519	EPSD	COSMIC;GDSC	3.025	Down-regulation
TK_InsR_IGF1R_Y	P08069	IGF1R	P08069	IGF1R	Y1346	G1351W	1351	Missense	distal	5	no	4.650	4.596	EPSD	COSMIC	3.025	Down-regulation
TK_InsR_IGF1R_Y	O15530	PDPK1	P08069	IGF1R	Y9	V12M	12	Missense	distal	3	no	2.720	3.105	EPSD	COSMIC	3.025	Gain
TK_InsR_IGF1R_Y	O15530	PDPK1	P08069	IGF1R	Y373	N378I	378	Missense	distal	5	no	4.041	3.924	EPSD;PhosphoSitePlus	COSMIC	3.025	Down-regulation
TK_InsR_IGF1R_Y	O15530	PDPK1	P08069	IGF1R	Y376	S381N	381	Missense	distal	5	no	5.561	5.421	PhosphoSitePlus;EPSD	COSMIC	3.025	Down-regulation
TK_InsR_IGF1R_Y	O15530	PDPK1	P08069	IGF1R	Y376	N378I	378	Missense	proximal	2	no	5.561	3.699	PhosphoSitePlus;EPSD	COSMIC	3.025	Down-regulation
TK_InsR_IGF1R_Y	P07355	ANXA2	P08069	IGF1R	Y24	K28Q	28	Missense	distal	4	no	3.818	3.901	PhosphoSitePlus	COSMIC;CCLE	3.025	Up-regulation
TK_InsR_IGF1R_Y	P07355	ANXA2	P08069	IGF1R	Y199	R196I	196	Missense	distal	-3	no	3.719	3.253	EPSD	COSMIC	3.025	Down-regulation
TK_InsR_IGF1R_Y	P12004	PCNA	P08069	IGF1R	Y60	R61H	61	Missense	proximal	1	no	4.859	4.958	EPSD;PhosphoSitePlus	COSMIC	3.025	Up-regulation
TK_InsR_IGF1R_Y	P12004	PCNA	P08069	IGF1R	Y133	K138N	138	Missense	distal	5	no	3.886	3.914	PhosphoSitePlus;EPSD	COSMIC	3.025	Up-regulation
TK_InsR_IGF1R_Y	P12004	PCNA	P08069	IGF1R	Y133	S134G	134	Missense	proximal	1	no	3.886	3.612	PhosphoSitePlus;EPSD	COSMIC	3.025	Down-regulation
TK_InsR_IGF1R_Y	P78324	SIRPA	P08069	IGF1R	Y496	A497V	497	Missense	proximal	1	no	3.937	3.696	PhosphoSitePlus;EPSD	COSMIC	3.025	Down-regulation
TK_InsR_IGF1R_Y	P78324	SIRPA	P08069	IGF1R	Y496	E490K	490	Missense	distal	-6	no	3.937	3.950	PhosphoSitePlus;EPSD	COSMIC	3.025	Up-regulation
TK_InsR_IGF1R_Y	P78324	SIRPA	P08069	IGF1R	Y496	P491T	491	Missense	distal	-5	no	3.937	3.993	PhosphoSitePlus;EPSD	COSMIC	3.025	Up-regulation
TKL_MLK_MLK_MAP3K10_ST	Q92630	DYRK2	Q02779	MAP3K10	S48	I50L	50	Missense	proximal	2	no	2.449	2.606	EPSD	COSMIC	2.080	Up-regulation
TKL_MLK_MLK_MAP3K10_ST	Q92630	DYRK2	Q02779	MAP3K10	S48	T44R	44	Missense	distal	-4	no	2.449	2.526	EPSD	COSMIC	2.080	Up-regulation
TKL_MLK_MLK_MAP3K10_ST	Q92630	DYRK2	Q02779	MAP3K10	T381	E375G	375	Missense	distal	-6	no	5.704	5.591	PhosphoSitePlus;EPSD	COSMIC;GDSC;CCLE	2.080	Down-regulation
TKL_MLK_MLK_MAP3K10_ST	Q92630	DYRK2	Q02779	MAP3K10	T381	Y388C	388	Missense	distal	7	no	5.704	5.483	PhosphoSitePlus;EPSD	COSMIC	2.080	Down-regulation
TKL_MLK_MLK_MAP3K10_ST	Q92630	DYRK2	Q02779	MAP3K10	T381	R378Q	378	Missense	distal	-3	no	5.704	5.468	PhosphoSitePlus;EPSD	COSMIC	2.080	Down-regulation
TKL_MLK_MLK_MAP3K10_ST	Q92630	DYRK2	Q02779	MAP3K10	S385	Y388C	388	Missense	distal	3	no	3.184	3.168	EPSD	COSMIC	2.080	Down-regulation
TKL_MLK_MLK_MAP3K10_ST	Q92630	DYRK2	Q02779	MAP3K10	S385	R378Q	378	Missense	distal	-7	no	3.184	3.296	EPSD	COSMIC	2.080	Up-regulation
TKL_MLK_MLK_MAP3K10_ST	Q92630	DYRK2	Q02779	MAP3K10	S449	F455V	455	Missense	distal	6	no	6.181	6.155	EPSD;PhosphoSitePlus	COSMIC	2.080	Down-regulation
TKL_MLK_MLK_MAP3K10_ST	Q92630	DYRK2	Q02779	MAP3K10	S471	V476I	476	Missense	distal	5	no	2.994	2.679	EPSD	COSMIC	2.080	Down-regulation
TKL_MLK_MLK_MAP3K10_ST	Q92630	DYRK2	Q02779	MAP3K10	S471	N478S	478	Missense	distal	7	no	2.994	2.610	EPSD	COSMIC	2.080	Down-regulation
TKL_MLK_MLK_MAP3K10_ST	Q92630	DYRK2	Q02779	MAP3K10	S471	G473C	473	Missense	proximal	2	no	2.994	3.072	EPSD	COSMIC	2.080	Up-regulation
TKL_MLK_MLK_MAP3K10_ST	Q92630	DYRK2	Q02779	MAP3K10	S471	G473D	473	Missense	proximal	2	no	2.994	3.063	EPSD	COSMIC	2.080	Up-regulation
TKL_MLK_MLK_MAP3K10_ST	Q92630	DYRK2	Q02779	MAP3K10	T525	G527C	527	Missense	proximal	2	no	2.710	2.788	EPSD	COSMIC	2.080	Up-regulation
TKL_MLK_MLK_MAP3K10_ST	Q92630	DYRK2	Q02779	MAP3K10	T525	R523H	523	Missense	proximal	-2	no	2.710	2.760	EPSD	COSMIC	2.080	Up-regulation
TKL_MLK_MLK_MAP3K10_ST	P15923	TCF3	Q02779	MAP3K10	S39	S39F	39	Missense	central	0	yes	2.468	0.000	EPSD	COSMIC	2.080	Loss
TKL_MLK_MLK_MAP3K10_ST	P15923	TCF3	Q02779	MAP3K10	S39	A43V	43	Missense	distal	4	no	2.468	2.349	EPSD	COSMIC	2.080	Down-regulation
TKL_MLK_MLK_MAP3K10_ST	P15923	TCF3	Q02779	MAP3K10	S39	G35D	35	Missense	distal	-4	no	2.468	2.426	EPSD	COSMIC	2.080	Down-regulation
TKL_MLK_MLK_MAP3K10_ST	P15923	TCF3	Q02779	MAP3K10	S139	S139F	139	Missense	central	0	yes	2.922	0.000	EPSD	COSMIC	2.080	Loss
TKL_MLK_MLK_MAP3K10_ST	P15923	TCF3	Q02779	MAP3K10	S139	S141L	141	Missense	proximal	2	no	2.922	3.106	EPSD	COSMIC	2.080	Up-regulation
TKL_MLK_MLK_MAP3K10_ST	P15923	TCF3	Q02779	MAP3K10	S139	P135L	135	Missense	distal	-4	no	2.922	2.921	EPSD	COSMIC	2.080	Down-regulation
TKL_MLK_MLK_MAP3K10_ST	P15923	TCF3	Q02779	MAP3K10	T168	A161V	161	Missense	distal	-7	no	2.130	1.861	EPSD	COSMIC	2.080	Loss
TKL_MLK_MLK_MAP3K10_ST	P15923	TCF3	Q02779	MAP3K10	T168	Q169E	169	Missense	proximal	1	no	2.130	2.557	EPSD	COSMIC	2.080	Up-regulation
TKL_MLK_MLK_MAP3K10_ST	P15923	TCF3	Q02779	MAP3K10	T168	R174W	174	Missense	distal	6	no	2.130	2.107	EPSD	COSMIC	2.080	Down-regulation
TKL_MLK_MLK_MAP3K10_ST	P15923	TCF3	Q02779	MAP3K10	T168	A161T	161	Missense	distal	-7	no	2.130	1.936	EPSD	COSMIC	2.080	Loss
TKL_MLK_MLK_MAP3K10_ST	P15923	TCF3	Q02779	MAP3K10	T168	D167E	167	Missense	proximal	-1	no	2.130	2.135	EPSD	COSMIC	2.080	Up-regulation
TKL_MLK_MLK_MAP3K10_ST	P15923	TCF3	Q02779	MAP3K10	S305	P309L	309	Missense	distal	4	no	2.628	2.619	EPSD	COSMIC;CCLE	2.080	Down-regulation
TKL_MLK_MLK_MAP3K10_ST	P15923	TCF3	Q02779	MAP3K10	T308	P309L	309	Missense	proximal	1	no	3.595	1.161	EPSD	COSMIC;CCLE	2.080	Loss
TKL_MLK_MLK_MAP3K10_ST	P15923	TCF3	Q02779	MAP3K10	T308	G313V	313	Missense	distal	5	no	3.595	3.833	EPSD	COSMIC	2.080	Up-regulation
TKL_MLK_MLK_MAP3K10_ST	P15923	TCF3	Q02779	MAP3K10	T308	G313R	313	Missense	distal	5	no	3.595	3.922	EPSD	COSMIC	2.080	Up-regulation
TKL_MLK_MLK_MAP3K10_ST	P15923	TCF3	Q02779	MAP3K10	S341	S346N	346	Missense	distal	5	no	5.783	6.036	EPSD;PhosphoSitePlus	COSMIC	2.080	Up-regulation
TKL_MLK_MLK_MAP3K10_ST	P15923	TCF3	Q02779	MAP3K10	S352	S346N	346	Missense	distal	-6	no	5.668	5.814	EPSD;PhosphoSitePlus	COSMIC	2.080	Up-regulation
TKL_MLK_MLK_MAP3K10_ST	P15923	TCF3	Q02779	MAP3K10	S352	P353L	353	Missense	proximal	1	no	5.668	3.234	EPSD;PhosphoSitePlus	COSMIC;CCLE	2.080	Down-regulation
TKL_MLK_MLK_MAP3K10_ST	P15923	TCF3	Q02779	MAP3K10	T355	P353L	353	Missense	proximal	-2	no	5.965	5.984	EPSD;PhosphoSitePlus	COSMIC;CCLE	2.080	Up-regulation
TKL_MLK_MLK_MAP3K10_ST	P15923	TCF3	Q02779	MAP3K10	T355	G362D	362	Missense	distal	7	no	5.965	6.049	EPSD;PhosphoSitePlus	COSMIC	2.080	Up-regulation
TKL_MLK_MLK_MAP3K10_ST	P15923	TCF3	Q02779	MAP3K10	S359	P353L	353	Missense	distal	-6	no	6.457	6.449	PhosphoSitePlus;EPSD	COSMIC;CCLE	2.080	Down-regulation
TKL_MLK_MLK_MAP3K10_ST	P15923	TCF3	Q02779	MAP3K10	S359	T366M	366	Missense	distal	7	no	6.457	6.334	PhosphoSitePlus;EPSD	COSMIC	2.080	Down-regulation
TKL_MLK_MLK_MAP3K10_ST	P15923	TCF3	Q02779	MAP3K10	S359	G362D	362	Missense	distal	3	no	6.457	6.496	PhosphoSitePlus;EPSD	COSMIC	2.080	Up-regulation
TKL_MLK_MLK_MAP3K10_ST	P15923	TCF3	Q02779	MAP3K10	S379	G373R	373	Missense	distal	-6	no	5.985	6.190	EPSD;PhosphoSitePlus	COSMIC	2.080	Up-regulation
TKL_MLK_MLK_MAP3K10_ST	P15923	TCF3	Q02779	MAP3K10	S379	G385S	385	Missense	distal	6	no	5.985	5.755	EPSD;PhosphoSitePlus	COSMIC	2.080	Down-regulation
TKL_MLK_MLK_MAP3K10_ST	P15923	TCF3	Q02779	MAP3K10	S379	G385R	385	Missense	distal	6	no	5.985	5.681	EPSD;PhosphoSitePlus	COSMIC	2.080	Down-regulation
AGC_DMPK_GEK_DMPK_ST	P11831	SRF	Q09013	DMPK	T159	R157C	157	Missense	proximal	-2	no	9.732	9.430	PhosphoSitePlus	COSMIC	2.483	Down-regulation
AGC_DMPK_GEK_DMPK_ST	P11831	SRF	Q09013	DMPK	T160	R157C	157	Missense	distal	-3	no	4.130	3.915	EPSD	COSMIC	2.483	Down-regulation
AGC_DMPK_GEK_DMPK_ST	P11831	SRF	Q09013	DMPK	T217	L219I	219	Missense	proximal	2	no	2.565	2.683	EPSD	COSMIC	2.483	Up-regulation
AGC_DMPK_GEK_DMPK_ST	P11831	SRF	Q09013	DMPK	S253	V250M	250	Missense	distal	-3	no	2.947	3.010	EPSD	COSMIC	2.483	Up-regulation
TKL_STKR_STKR2_TGFBR2_ST	P36897	TGFBR1	P37173	TGFBR2	S165	R168C	168	Missense	distal	3	no	1.496	1.519	EPSD	COSMIC	0.983	Up-regulation
TKL_STKR_STKR2_TGFBR2_ST	P36897	TGFBR1	P37173	TGFBR2	S165	P159S	159	Missense	distal	-6	no	1.496	1.463	EPSD	COSMIC	0.983	Down-regulation
TKL_STKR_STKR2_TGFBR2_ST	P36897	TGFBR1	P37173	TGFBR2	S165	R168H	168	Missense	distal	3	no	1.496	1.418	EPSD	COSMIC	0.983	Down-regulation
TKL_STKR_STKR2_TGFBR2_ST	P36897	TGFBR1	P37173	TGFBR2	S165	E161K	161	Missense	distal	-4	no	1.496	1.520	EPSD	COSMIC	0.983	Up-regulation
TKL_STKR_STKR2_TGFBR2_ST	P36897	TGFBR1	P37173	TGFBR2	S165	S172L	172	Missense	distal	7	no	1.496	1.491	EPSD	COSMIC	0.983	Down-regulation
TKL_STKR_STKR2_TGFBR2_ST	P36897	TGFBR1	P37173	TGFBR2	S165	R168K	168	Missense	distal	3	no	1.496	1.451	EPSD	COSMIC	0.983	Down-regulation
TKL_STKR_STKR2_TGFBR2_ST	P36897	TGFBR1	P37173	TGFBR2	T175	S172L	172	Missense	distal	-3	no	0.815	1.070	EPSD	COSMIC	0.983	Gain
TKL_STKR_STKR2_TGFBR2_ST	P36897	TGFBR1	P37173	TGFBR2	T185	G192S	192	Missense	distal	7	no	1.780	1.790	PhosphoSitePlus;EPSD	COSMIC	0.983	Up-regulation
TKL_STKR_STKR2_TGFBR2_ST	P36897	TGFBR1	P37173	TGFBR2	T185	G192C	192	Missense	distal	7	no	1.780	1.776	PhosphoSitePlus;EPSD	COSMIC	0.983	Down-regulation
TKL_STKR_STKR2_TGFBR2_ST	P36897	TGFBR1	P37173	TGFBR2	T185	Y182C	182	Missense	distal	-3	no	1.780	1.760	PhosphoSitePlus;EPSD	COSMIC	0.983	Down-regulation
TKL_STKR_STKR2_TGFBR2_ST	P36897	TGFBR1	P37173	TGFBR2	T185	G188D	188	Missense	distal	3	no	1.780	1.843	PhosphoSitePlus;EPSD	COSMIC	0.983	Up-regulation
TKL_STKR_STKR2_TGFBR2_ST	P36897	TGFBR1	P37173	TGFBR2	T185	M184I	184	Missense	proximal	-1	no	1.780	1.742	PhosphoSitePlus;EPSD	COSMIC	0.983	Down-regulation
TKL_STKR_STKR2_TGFBR2_ST	P36897	TGFBR1	P37173	TGFBR2	T185	G192E	192	Missense	distal	7	no	1.780	1.786	PhosphoSitePlus;EPSD	COSMIC	0.983	Up-regulation
TKL_STKR_STKR2_TGFBR2_ST	P36897	TGFBR1	P37173	TGFBR2	T186	G192S	192	Missense	distal	6	no	1.939	2.011	EPSD;PhosphoSitePlus	COSMIC	0.983	Up-regulation
TKL_STKR_STKR2_TGFBR2_ST	P36897	TGFBR1	P37173	TGFBR2	T186	L193S	193	Missense	distal	7	no	1.939	1.944	EPSD;PhosphoSitePlus	COSMIC	0.983	Up-regulation
TKL_STKR_STKR2_TGFBR2_ST	P36897	TGFBR1	P37173	TGFBR2	T186	G192C	192	Missense	distal	6	no	1.939	1.913	EPSD;PhosphoSitePlus	COSMIC	0.983	Down-regulation
TKL_STKR_STKR2_TGFBR2_ST	P36897	TGFBR1	P37173	TGFBR2	T186	Y182C	182	Missense	distal	-4	no	1.939	1.938	EPSD;PhosphoSitePlus	COSMIC	0.983	Down-regulation
TKL_STKR_STKR2_TGFBR2_ST	P36897	TGFBR1	P37173	TGFBR2	T186	G188D	188	Missense	proximal	2	no	1.939	1.991	EPSD;PhosphoSitePlus	COSMIC	0.983	Up-regulation
TKL_STKR_STKR2_TGFBR2_ST	P36897	TGFBR1	P37173	TGFBR2	T186	G192D	192	Missense	distal	6	no	1.939	1.933	EPSD;PhosphoSitePlus	COSMIC	0.983	Down-regulation
TKL_STKR_STKR2_TGFBR2_ST	P36897	TGFBR1	P37173	TGFBR2	T186	M184I	184	Missense	proximal	-2	no	1.939	1.968	EPSD;PhosphoSitePlus	COSMIC	0.983	Up-regulation
TKL_STKR_STKR2_TGFBR2_ST	P36897	TGFBR1	P37173	TGFBR2	T186	G192E	192	Missense	distal	6	no	1.939	2.011	EPSD;PhosphoSitePlus	COSMIC	0.983	Up-regulation
TKL_STKR_STKR2_TGFBR2_ST	P36897	TGFBR1	P37173	TGFBR2	S187	G192S	192	Missense	distal	5	no	2.011	2.003	EPSD;PhosphoSitePlus	COSMIC	0.983	Down-regulation
TKL_STKR_STKR2_TGFBR2_ST	P36897	TGFBR1	P37173	TGFBR2	S187	L193S	193	Missense	distal	6	no	2.011	1.978	EPSD;PhosphoSitePlus	COSMIC	0.983	Down-regulation
TKL_STKR_STKR2_TGFBR2_ST	P36897	TGFBR1	P37173	TGFBR2	S187	G192C	192	Missense	distal	5	no	2.011	2.016	EPSD;PhosphoSitePlus	COSMIC	0.983	Up-regulation
TKL_STKR_STKR2_TGFBR2_ST	P36897	TGFBR1	P37173	TGFBR2	S187	Y182C	182	Missense	distal	-5	no	2.011	1.943	EPSD;PhosphoSitePlus	COSMIC	0.983	Down-regulation
TKL_STKR_STKR2_TGFBR2_ST	P36897	TGFBR1	P37173	TGFBR2	S187	G188D	188	Missense	proximal	1	no	2.011	1.965	EPSD;PhosphoSitePlus	COSMIC	0.983	Down-regulation
TKL_STKR_STKR2_TGFBR2_ST	P36897	TGFBR1	P37173	TGFBR2	S187	M184I	184	Missense	distal	-3	no	2.011	1.807	EPSD;PhosphoSitePlus	COSMIC	0.983	Down-regulation
TKL_STKR_STKR2_TGFBR2_ST	P36897	TGFBR1	P37173	TGFBR2	S187	G192E	192	Missense	distal	5	no	2.011	2.010	EPSD;PhosphoSitePlus	COSMIC	0.983	Down-regulation
TKL_STKR_STKR2_TGFBR2_ST	P36897	TGFBR1	P37173	TGFBR2	S189	G192S	192	Missense	distal	3	no	1.713	1.744	EPSD;PhosphoSitePlus	COSMIC	0.983	Up-regulation
TKL_STKR_STKR2_TGFBR2_ST	P36897	TGFBR1	P37173	TGFBR2	S189	L195F	195	Missense	distal	6	no	1.713	1.603	EPSD;PhosphoSitePlus	COSMIC	0.983	Down-regulation
TKL_STKR_STKR2_TGFBR2_ST	P36897	TGFBR1	P37173	TGFBR2	S189	L193S	193	Missense	distal	4	no	1.713	1.696	EPSD;PhosphoSitePlus	COSMIC	0.983	Down-regulation
TKL_STKR_STKR2_TGFBR2_ST	P36897	TGFBR1	P37173	TGFBR2	S189	G192C	192	Missense	distal	3	no	1.713	1.828	EPSD;PhosphoSitePlus	COSMIC	0.983	Up-regulation
TKL_STKR_STKR2_TGFBR2_ST	P36897	TGFBR1	P37173	TGFBR2	S189	Y182C	182	Missense	distal	-7	no	1.713	1.719	EPSD;PhosphoSitePlus	COSMIC	0.983	Up-regulation
TKL_STKR_STKR2_TGFBR2_ST	P36897	TGFBR1	P37173	TGFBR2	S189	G188D	188	Missense	proximal	-1	no	1.713	1.727	EPSD;PhosphoSitePlus	COSMIC	0.983	Up-regulation
TKL_STKR_STKR2_TGFBR2_ST	P36897	TGFBR1	P37173	TGFBR2	S189	G192D	192	Missense	distal	3	no	1.713	1.775	EPSD;PhosphoSitePlus	COSMIC	0.983	Up-regulation
TKL_STKR_STKR2_TGFBR2_ST	P36897	TGFBR1	P37173	TGFBR2	S189	M184I	184	Missense	distal	-5	no	1.713	1.777	EPSD;PhosphoSitePlus	COSMIC	0.983	Up-regulation
TKL_STKR_STKR2_TGFBR2_ST	P36897	TGFBR1	P37173	TGFBR2	S189	G192E	192	Missense	distal	3	no	1.713	1.728	EPSD;PhosphoSitePlus	COSMIC	0.983	Up-regulation
TKL_STKR_STKR2_TGFBR2_ST	P36897	TGFBR1	P37173	TGFBR2	S191	L195F	195	Missense	distal	4	no	1.909	1.931	EPSD;PhosphoSitePlus	COSMIC	0.983	Up-regulation
TKL_STKR_STKR2_TGFBR2_ST	P36897	TGFBR1	P37173	TGFBR2	S191	L193S	193	Missense	proximal	2	no	1.909	2.037	EPSD;PhosphoSitePlus	COSMIC	0.983	Up-regulation
TKL_STKR_STKR2_TGFBR2_ST	P36897	TGFBR1	P37173	TGFBR2	S191	G192C	192	Missense	proximal	1	no	1.909	1.832	EPSD;PhosphoSitePlus	COSMIC	0.983	Down-regulation
TKL_STKR_STKR2_TGFBR2_ST	P36897	TGFBR1	P37173	TGFBR2	S191	G188D	188	Missense	distal	-3	no	1.909	1.926	EPSD;PhosphoSitePlus	COSMIC	0.983	Up-regulation
TKL_STKR_STKR2_TGFBR2_ST	P36897	TGFBR1	P37173	TGFBR2	S191	G192D	192	Missense	proximal	1	no	1.909	1.862	EPSD;PhosphoSitePlus	COSMIC	0.983	Down-regulation
TKL_STKR_STKR2_TGFBR2_ST	P36897	TGFBR1	P37173	TGFBR2	S191	M184I	184	Missense	distal	-7	no	1.909	1.891	EPSD;PhosphoSitePlus	COSMIC	0.983	Down-regulation
TKL_STKR_STKR2_TGFBR2_ST	P36897	TGFBR1	P37173	TGFBR2	S191	G192E	192	Missense	proximal	1	no	1.909	1.916	EPSD;PhosphoSitePlus	COSMIC	0.983	Up-regulation
TKL_STKR_STKR2_TGFBR2_ST	P36897	TGFBR1	P37173	TGFBR2	T296	G301E	301	Missense	distal	5	no	0.990	0.989	EPSD	COSMIC	0.983	Down-regulation
TKL_STKR_STKR2_TGFBR2_ST	P36897	TGFBR1	P37173	TGFBR2	T296	N293S	293	Missense	distal	-3	no	0.990	0.887	EPSD	COSMIC	0.983	Loss
TKL_STKR_STKR2_TGFBR2_ST	P36897	TGFBR1	P37173	TGFBR2	T296	R294S	294	Missense	proximal	-2	no	0.990	1.009	EPSD	COSMIC	0.983	Up-regulation
TKL_STKR_STKR2_TGFBR2_ST	P36897	TGFBR1	P37173	TGFBR2	T296	L292F	292	Missense	distal	-4	no	0.990	0.958	EPSD	COSMIC	0.983	Loss
TKL_STKR_STKR2_TGFBR2_ST	P36897	TGFBR1	P37173	TGFBR2	T296	T298I	298	Missense	proximal	2	no	0.990	1.007	EPSD	COSMIC	0.983	Up-regulation
TKL_STKR_STKR2_TGFBR2_ST	P36897	TGFBR1	P37173	TGFBR2	T296	Y295F	295	Missense	proximal	-1	no	0.990	0.996	EPSD	COSMIC;GDSC;CCLE	0.983	Up-regulation
TKL_STKR_STKR2_TGFBR2_ST	P36897	TGFBR1	P37173	TGFBR2	T296	T298K	298	Missense	proximal	2	no	0.990	0.913	EPSD	COSMIC	0.983	Loss
TKL_STKR_STKR2_TGFBR2_ST	P36897	TGFBR1	P37173	TGFBR2	T296	T298R	298	Missense	proximal	2	no	0.990	0.945	EPSD	COSMIC	0.983	Loss
TKL_STKR_STKR2_TGFBR2_ST	P36897	TGFBR1	P37173	TGFBR2	T296	D290G	290	Missense	distal	-6	no	0.990	0.984	EPSD	COSMIC	0.983	Down-regulation
TKL_STKR_STKR2_TGFBR2_ST	P37173	TGFBR2	P37173	TGFBR2	S213	T206M	206	Missense	distal	-7	no	1.789	1.801	EPSD;PhosphoSitePlus	COSMIC;CCLE	0.983	Up-regulation
TKL_STKR_STKR2_TGFBR2_ST	P37173	TGFBR2	P37173	TGFBR2	S213	I218M	218	Missense	distal	5	no	1.789	1.798	EPSD;PhosphoSitePlus	COSMIC	0.983	Up-regulation
TKL_STKR_STKR2_TGFBR2_ST	P37173	TGFBR2	P37173	TGFBR2	S213	L209F	209	Missense	distal	-4	no	1.789	1.757	EPSD;PhosphoSitePlus	COSMIC	0.983	Down-regulation
TKL_STKR_STKR2_TGFBR2_ST	P37173	TGFBR2	P37173	TGFBR2	S213	R207Q	207	Missense	distal	-6	no	1.789	1.747	EPSD;PhosphoSitePlus	COSMIC	0.983	Down-regulation
TKL_STKR_STKR2_TGFBR2_ST	P37173	TGFBR2	P37173	TGFBR2	S213	R207W	207	Missense	distal	-6	no	1.789	1.844	EPSD;PhosphoSitePlus	COSMIC;CCLE	0.983	Up-regulation
TKL_STKR_STKR2_TGFBR2_ST	P37173	TGFBR2	P37173	TGFBR2	S213	E214K	214	Missense	proximal	1	no	1.789	1.732	EPSD;PhosphoSitePlus	COSMIC	0.983	Down-regulation
TKL_STKR_STKR2_TGFBR2_ST	P37173	TGFBR2	P37173	TGFBR2	S213	S213I	213	Missense	central	0	yes	1.789	0.000	EPSD;PhosphoSitePlus	COSMIC	0.983	Loss
TKL_STKR_STKR2_TGFBR2_ST	P37173	TGFBR2	P37173	TGFBR2	S213	E214G	214	Missense	proximal	1	no	1.789	1.782	EPSD;PhosphoSitePlus	COSMIC	0.983	Down-regulation
TKL_STKR_STKR2_TGFBR2_ST	P37173	TGFBR2	P37173	TGFBR2	S409	R403M	403	Missense	distal	-6	no	1.938	1.949	EPSD;PhosphoSitePlus	COSMIC;GDSC	0.983	Up-regulation
TKL_STKR_STKR2_TGFBR2_ST	P37173	TGFBR2	P37173	TGFBR2	S409	R403W	403	Missense	distal	-6	no	1.938	1.994	EPSD;PhosphoSitePlus	COSMIC	0.983	Up-regulation
TKL_STKR_STKR2_TGFBR2_ST	P37173	TGFBR2	P37173	TGFBR2	S409	R403G	403	Missense	distal	-6	no	1.938	1.977	EPSD;PhosphoSitePlus	COSMIC	0.983	Up-regulation
TKL_STKR_STKR2_TGFBR2_ST	P37173	TGFBR2	P37173	TGFBR2	S409	R403K	403	Missense	distal	-6	no	1.938	1.925	EPSD;PhosphoSitePlus	COSMIC	0.983	Down-regulation
TKL_STKR_STKR2_TGFBR2_ST	P37173	TGFBR2	P37173	TGFBR2	S409	R403H	403	Missense	distal	-6	no	1.938	1.929	EPSD;PhosphoSitePlus	COSMIC;CCLE	0.983	Down-regulation
TKL_STKR_STKR2_TGFBR2_ST	P37173	TGFBR2	P37173	TGFBR2	S409	L408P	408	Missense	proximal	-1	no	1.938	1.959	EPSD;PhosphoSitePlus	COSMIC	0.983	Up-regulation
TKL_STKR_STKR2_TGFBR2_ST	P37173	TGFBR2	P37173	TGFBR2	S409	D411Y	411	Missense	proximal	2	no	1.938	1.805	EPSD;PhosphoSitePlus	COSMIC	0.983	Down-regulation
TKL_STKR_STKR2_TGFBR2_ST	P37173	TGFBR2	P37173	TGFBR2	S409	D412H	412	Missense	distal	3	no	1.938	1.891	EPSD;PhosphoSitePlus	COSMIC	0.983	Down-regulation
TKL_STKR_STKR2_TGFBR2_ST	P37173	TGFBR2	P37173	TGFBR2	S409	L404R	404	Missense	distal	-5	no	1.938	1.882	EPSD;PhosphoSitePlus	COSMIC	0.983	Down-regulation
TKL_STKR_STKR2_TGFBR2_ST	P37173	TGFBR2	P37173	TGFBR2	S409	L402P	402	Missense	distal	-7	no	1.938	1.955	EPSD;PhosphoSitePlus	COSMIC	0.983	Up-regulation
TKL_STKR_STKR2_TGFBR2_ST	P37173	TGFBR2	P37173	TGFBR2	S416	A414D	414	Missense	proximal	-2	no	1.977	1.974	EPSD;PhosphoSitePlus	COSMIC	0.983	Down-regulation
TKL_STKR_STKR2_TGFBR2_ST	P37173	TGFBR2	P37173	TGFBR2	S416	D411Y	411	Missense	distal	-5	no	1.977	2.060	EPSD;PhosphoSitePlus	COSMIC	0.983	Up-regulation
TKL_STKR_STKR2_TGFBR2_ST	P37173	TGFBR2	P37173	TGFBR2	S416	V419M	419	Missense	distal	3	no	1.977	1.898	EPSD;PhosphoSitePlus	COSMIC	0.983	Down-regulation
TKL_STKR_STKR2_TGFBR2_ST	P37173	TGFBR2	P37173	TGFBR2	S416	D412H	412	Missense	distal	-4	no	1.977	1.934	EPSD;PhosphoSitePlus	COSMIC	0.983	Down-regulation
TKL_STKR_STKR2_TGFBR2_ST	P37173	TGFBR2	P37173	TGFBR2	S416	G420R	420	Missense	distal	4	no	1.977	1.991	EPSD;PhosphoSitePlus	COSMIC	0.983	Up-regulation
TKL_STKR_STKR2_TGFBR2_ST	P37173	TGFBR2	P37173	TGFBR2	S416	A422T	422	Missense	distal	6	no	1.977	1.998	EPSD;PhosphoSitePlus	COSMIC	0.983	Up-regulation
TKL_STKR_STKR2_TGFBR2_ST	O75604	USP2	P37173	TGFBR2	S58	R62H	62	Missense	distal	4	no	0.988	0.972	EPSD	COSMIC;GDSC;CCLE	0.983	Loss
TKL_STKR_STKR2_TGFBR2_ST	O75604	USP2	P37173	TGFBR2	S58	P53L	53	Missense	distal	-5	no	0.988	1.100	EPSD	COSMIC;GDSC	0.983	Up-regulation
TKL_STKR_STKR2_TGFBR2_ST	O75604	USP2	P37173	TGFBR2	S169	P170L	170	Missense	proximal	1	no	1.011	1.016	EPSD	COSMIC	0.983	Up-regulation
TKL_STKR_STKR2_TGFBR2_ST	O75604	USP2	P37173	TGFBR2	S169	N165K	165	Missense	distal	-4	no	1.011	1.019	EPSD	COSMIC;GDSC;CCLE	0.983	Up-regulation
TKL_STKR_STKR2_TGFBR2_ST	O75604	USP2	P37173	TGFBR2	T175	P170L	170	Missense	distal	-5	no	1.091	1.204	EPSD	COSMIC	0.983	Up-regulation
TKL_STKR_STKR2_TGFBR2_ST	O75604	USP2	P37173	TGFBR2	T175	T181M	181	Missense	distal	6	no	1.091	1.067	EPSD	COSMIC	0.983	Down-regulation
TKL_STKR_STKR2_TGFBR2_ST	O75604	USP2	P37173	TGFBR2	S207	S213L	213	Missense	distal	6	no	1.937	1.970	PhosphoSitePlus;EPSD	COSMIC	0.983	Up-regulation
TKL_STKR_STKR2_TGFBR2_ST	O75604	USP2	P37173	TGFBR2	S207	Y202C	202	Missense	distal	-5	no	1.937	1.869	PhosphoSitePlus;EPSD	COSMIC;GDSC;CCLE	0.983	Down-regulation
TKL_STKR_STKR2_TGFBR2_ST	O75604	USP2	P37173	TGFBR2	S225	S225G	225	Missense	central	0	yes	1.792	0.000	EPSD;PhosphoSitePlus	COSMIC	0.983	Loss
TKL_STKR_STKR2_TGFBR2_ST	O75604	USP2	P37173	TGFBR2	S225	R229L	229	Missense	distal	4	no	1.792	1.763	EPSD;PhosphoSitePlus	COSMIC;GDSC;CCLE	0.983	Down-regulation
CMGC_CLK_CLK1_ST	P00519	ABL1	P49759	CLK1	S157	P158L	158	Missense	proximal	1	no	58.424	58.717	EPSD	COSMIC	52.547	Up-regulation
CMGC_CLK_CLK1_ST	P00519	ABL1	P49759	CLK1	S157	E155K	155	Missense	proximal	-2	no	58.424	62.141	EPSD	COSMIC	52.547	Up-regulation
CMGC_CLK_CLK1_ST	P00519	ABL1	P49759	CLK1	S157	S162F	162	Missense	distal	5	no	58.424	52.882	EPSD	COSMIC	52.547	Down-regulation
CMGC_CLK_CLK1_ST	P00519	ABL1	P49759	CLK1	S157	S156N	156	Missense	proximal	-1	no	58.424	58.468	EPSD	COSMIC	52.547	Up-regulation
CMGC_CLK_CLK1_ST	P00519	ABL1	P49759	CLK1	S187	L184R	184	Missense	distal	-3	no	30.637	55.668	EPSD	COSMIC	52.547	Gain
CMGC_CLK_CLK1_ST	P00519	ABL1	P49759	CLK1	S265	K263N	263	Missense	proximal	-2	no	52.167	53.149	EPSD	COSMIC	52.547	Gain
CMGC_CLK_CLK1_ST	P00519	ABL1	P49759	CLK1	S265	V268A	268	Missense	distal	3	no	52.167	53.213	EPSD	COSMIC	52.547	Gain
CMGC_CLK_CLK1_ST	P00519	ABL1	P49759	CLK1	S265	V260A	260	Missense	distal	-5	no	52.167	53.488	EPSD	COSMIC	52.547	Gain
CMGC_CLK_CLK1_ST	P00519	ABL1	P49759	CLK1	S601	N598D	598	Missense	distal	-3	no	38.825	53.337	EPSD	COSMIC;CCLE	52.547	Gain
CMGC_CLK_CLK1_ST	P00519	ABL1	P49759	CLK1	T613	K616R	616	Missense	distal	3	no	57.730	58.352	EPSD	COSMIC	52.547	Up-regulation
CMGC_CLK_CLK1_ST	P00519	ABL1	P49759	CLK1	S620	G626D	626	Missense	distal	6	no	68.910	70.053	EPSD	COSMIC	52.547	Up-regulation
CMGC_CLK_CLK1_ST	P00519	ABL1	P49759	CLK1	S620	G626S	626	Missense	distal	6	no	68.910	71.472	EPSD	COSMIC	52.547	Up-regulation
CMGC_CLK_CLK1_ST	P00519	ABL1	P49759	CLK1	S620	K616R	616	Missense	distal	-4	no	68.910	68.932	EPSD	COSMIC	52.547	Up-regulation
CMGC_CLK_CLK1_ST	P00519	ABL1	P49759	CLK1	S642	G644V	644	Missense	proximal	2	no	70.448	70.273	EPSD	COSMIC	52.547	Down-regulation
CMGC_CLK_CLK1_ST	P00519	ABL1	P49759	CLK1	S659	P662L	662	Missense	distal	3	no	53.942	54.003	EPSD	COSMIC;CCLE	52.547	Up-regulation
CMGC_CLK_CLK1_ST	P00519	ABL1	P49759	CLK1	S659	S663R	663	Missense	distal	4	no	53.942	53.877	EPSD	COSMIC	52.547	Down-regulation
CMGC_CLK_CLK1_ST	P00519	ABL1	P49759	CLK1	S659	G665L	665	Missense	distal	6	no	53.942	55.439	EPSD	COSMIC	52.547	Up-regulation
CMGC_CLK_CLK1_ST	P00519	ABL1	P49759	CLK1	S659	K658N	658	Missense	proximal	-1	no	53.942	53.944	EPSD	COSMIC	52.547	Up-regulation
CMGC_CLK_CLK1_ST	P00519	ABL1	P49759	CLK1	S695	G701C	701	Missense	distal	6	no	56.336	56.755	EPSD	COSMIC	52.547	Up-regulation
CMGC_CLK_CLK1_ST	P00519	ABL1	P49759	CLK1	S709	G706V	706	Missense	distal	-3	no	47.193	53.389	EPSD	COSMIC	52.547	Gain
CMGC_CLK_CLK1_ST	P00519	ABL1	P49759	CLK1	S718	G725S	725	Missense	distal	7	no	60.359	64.309	EPSD	COSMIC	52.547	Up-regulation
CMGC_CLK_CLK1_ST	P00519	ABL1	P49759	CLK1	S718	G725V	725	Missense	distal	7	no	60.359	64.911	EPSD	COSMIC	52.547	Up-regulation
CMGC_CLK_CLK1_ST	P00519	ABL1	P49759	CLK1	S718	H724R	724	Missense	distal	6	no	60.359	62.009	EPSD	COSMIC	52.547	Up-regulation
CMGC_CLK_CLK1_ST	P00519	ABL1	P49759	CLK1	S718	C717F	717	Missense	proximal	-1	no	60.359	60.360	EPSD	COSMIC	52.547	Up-regulation
CMGC_CLK_CLK1_ST	P00519	ABL1	P49759	CLK1	S718	A719T	719	Missense	proximal	1	no	60.359	61.835	EPSD	COSMIC	52.547	Up-regulation
CMGC_CLK_CLK1_ST	P00519	ABL1	P49759	CLK1	S718	S720F	720	Missense	proximal	2	no	60.359	59.389	EPSD	COSMIC	52.547	Down-regulation
CMGC_CLK_CLK1_ST	P00519	ABL1	P49759	CLK1	S718	V722I	722	Missense	distal	4	no	60.359	60.548	EPSD	COSMIC	52.547	Up-regulation
CMGC_CLK_CLK1_ST	P00519	ABL1	P49759	CLK1	T735	T729M	729	Missense	distal	-6	no	96.105	94.166	PhosphoSitePlus	COSMIC	52.547	Down-regulation
CMGC_CLK_CLK1_ST	P00519	ABL1	P49759	CLK1	T735	R732G	732	Missense	distal	-3	no	96.105	55.694	PhosphoSitePlus	COSMIC	52.547	Down-regulation
CMGC_CLK_CLK1_ST	P00519	ABL1	P49759	CLK1	T735	R732S	732	Missense	distal	-3	no	96.105	79.216	PhosphoSitePlus	COSMIC	52.547	Down-regulation
CMGC_CLK_CLK1_ST	P00519	ABL1	P49759	CLK1	T735	R738Q	738	Missense	distal	3	no	96.105	95.052	PhosphoSitePlus	COSMIC	52.547	Down-regulation
CMGC_CLK_CLK1_ST	P00519	ABL1	P49759	CLK1	T735	R738W	738	Missense	distal	3	no	96.105	94.314	PhosphoSitePlus	COSMIC	52.547	Down-regulation
CMGC_CLK_CLK1_ST	P00519	ABL1	P49759	CLK1	S840	G837R	837	Missense	distal	-3	no	39.455	79.866	EPSD	COSMIC	52.547	Gain
CMGC_CLK_CLK1_ST	P00519	ABL1	P49759	CLK1	S859	G864S	864	Missense	distal	5	no	49.037	55.680	EPSD	COSMIC	52.547	Gain
CMGC_CLK_CLK1_ST	P00519	ABL1	P49759	CLK1	S884	H878R	878	Missense	distal	-6	no	45.644	53.501	EPSD	COSMIC	52.547	Gain
CMGC_CLK_CLK1_ST	P00519	ABL1	P49759	CLK1	S919	G924R	924	Missense	distal	5	no	51.548	55.864	EPSD	COSMIC	52.547	Gain
CMGC_CLK_CLK1_ST	P00519	ABL1	P49759	CLK1	S919	G924E	924	Missense	distal	5	no	51.548	52.644	EPSD	COSMIC	52.547	Gain
CMGC_CLK_CLK1_ST	P00519	ABL1	P49759	CLK1	S936	S943T	943	Missense	distal	7	no	55.186	52.604	EPSD	COSMIC	52.547	Down-regulation
CMGC_CLK_CLK1_ST	P00519	ABL1	P49759	CLK1	S968	P961Q	961	Missense	distal	-7	no	47.234	58.182	EPSD	COSMIC	52.547	Gain
CMGC_CLK_CLK1_ST	P00519	ABL1	P49759	CLK1	S977	P982S	982	Missense	distal	5	no	49.575	53.883	EPSD	COSMIC	52.547	Gain
CMGC_CLK_CLK1_ST	P00519	ABL1	P49759	CLK1	S989	P986S	986	Missense	distal	-3	no	38.336	57.846	EPSD	COSMIC	52.547	Gain
CMGC_CLK_CLK1_ST	P00519	ABL1	P49759	CLK1	S1011	R1009L	1009	Missense	proximal	-2	no	56.202	48.078	EPSD	COSMIC	52.547	Loss
CMGC_CLK_CLK1_ST	P00519	ABL1	P49759	CLK1	S1011	L1012V	1012	Missense	proximal	1	no	56.202	55.936	EPSD	COSMIC	52.547	Down-regulation
CMGC_CLK_CLK1_ST	P00519	ABL1	P49759	CLK1	S1011	R1016S	1016	Missense	distal	5	no	56.202	58.529	EPSD	COSMIC	52.547	Up-regulation
CMGC_CLK_CLK1_ST	P00519	ABL1	P49759	CLK1	S1011	P1018H	1018	Missense	distal	7	no	56.202	54.009	EPSD	COSMIC	52.547	Down-regulation
CMGC_CLK_CLK1_ST	P00519	ABL1	P49759	CLK1	S1119	F1114L	1114	Missense	distal	-5	no	48.777	57.238	EPSD	COSMIC	52.547	Gain
CMGC_CLK_CLK1_ST	Q96I25	RBM17	P49759	CLK1	S48	T45M	45	Missense	distal	-3	no	95.061	76.880	EPSD;PhosphoSitePlus	COSMIC	52.547	Down-regulation
CMGC_CLK_CLK1_ST	Q96I25	RBM17	P49759	CLK1	S48	S48G	48	Missense	central	0	yes	95.061	0.000	EPSD;PhosphoSitePlus	COSMIC	52.547	Loss
CMGC_CLK_CLK1_ST	Q96I25	RBM17	P49759	CLK1	S62	S63L	63	Missense	proximal	1	no	98.929	99.792	EPSD;PhosphoSitePlus	COSMIC	52.547	Up-regulation
CMGC_CLK_CLK1_ST	Q96I25	RBM17	P49759	CLK1	S62	R66Q	66	Missense	distal	4	no	98.929	100.119	EPSD;PhosphoSitePlus	COSMIC	52.547	Up-regulation
CMGC_CLK_CLK1_ST	Q96I25	RBM17	P49759	CLK1	S62	D65E	65	Missense	distal	3	no	98.929	98.879	EPSD;PhosphoSitePlus	COSMIC	52.547	Down-regulation
CMGC_CLK_CLK1_ST	Q96I25	RBM17	P49759	CLK1	S169	A176T	176	Missense	distal	7	no	64.032	61.354	EPSD	COSMIC;GDSC;CCLE	52.547	Down-regulation
CMGC_CLK_CLK1_ST	Q96I25	RBM17	P49759	CLK1	S169	R168I	168	Missense	proximal	-1	no	64.032	64.046	EPSD	COSMIC	52.547	Up-regulation
CMGC_CLK_CLK1_ST	Q96I25	RBM17	P49759	CLK1	S202	R199I	199	Missense	distal	-3	no	94.284	77.759	EPSD;PhosphoSitePlus	COSMIC	52.547	Down-regulation
CMGC_CLK_CLK1_ST	Q96I25	RBM17	P49759	CLK1	S204	R199I	199	Missense	distal	-5	no	109.284	99.788	EPSD;PhosphoSitePlus	COSMIC	52.547	Down-regulation
CMGC_CLK_CLK1_ST	Q96I25	RBM17	P49759	CLK1	S222	S229F	229	Missense	distal	7	no	100.524	97.903	PhosphoSitePlus;EPSD	COSMIC	52.547	Down-regulation
CMGC_CLK_CLK1_ST	Q96I25	RBM17	P49759	CLK1	S222	G225R	225	Missense	distal	3	no	100.524	102.861	PhosphoSitePlus;EPSD	COSMIC	52.547	Up-regulation
CMGC_CLK_CLK1_ST	Q96I25	RBM17	P49759	CLK1	T224	S229F	229	Missense	distal	5	no	68.289	62.747	EPSD	COSMIC	52.547	Down-regulation
CMGC_CLK_CLK1_ST	Q96I25	RBM17	P49759	CLK1	T224	G225R	225	Missense	proximal	1	no	68.289	67.003	EPSD	COSMIC	52.547	Down-regulation
CMGC_CLK_CLK1_ST	Q96I25	RBM17	P49759	CLK1	S227	G225R	225	Missense	proximal	-2	no	51.161	53.736	EPSD	COSMIC	52.547	Gain
CMGC_CLK_CLK1_ST	Q96I25	RBM17	P49759	CLK1	S266	S266P	266	Missense	central	0	yes	96.706	0.000	EPSD;PhosphoSitePlus	COSMIC	52.547	Loss
CMGC_CLK_CLK1_ST	Q96I25	RBM17	P49759	CLK1	S266	G260C	260	Missense	distal	-6	no	96.706	90.748	EPSD;PhosphoSitePlus	COSMIC	52.547	Down-regulation
CMGC_CLK_CLK1_ST	Q96I25	RBM17	P49759	CLK1	S266	S262N	262	Missense	distal	-4	no	96.706	96.452	EPSD;PhosphoSitePlus	COSMIC	52.547	Down-regulation
CMGC_CLK_CLK1_ST	Q96I25	RBM17	P49759	CLK1	S288	A282T	282	Missense	distal	-6	no	100.958	103.547	EPSD;PhosphoSitePlus	COSMIC;GDSC;CCLE	52.547	Up-regulation
CMGC_CLK_CLK1_ST	P18031	PTPN1	P49759	CLK1	S50	I57V	57	Missense	distal	7	no	105.509	105.891	EPSD;PhosphoSitePlus	COSMIC;GDSC;CCLE	52.547	Up-regulation
CMGC_CLK_CLK1_ST	P18031	PTPN1	P49759	CLK1	S50	F52L	52	Missense	proximal	2	no	105.509	105.700	EPSD;PhosphoSitePlus	COSMIC	52.547	Up-regulation
CMGC_CLK_CLK1_ST	P18031	PTPN1	P49759	CLK1	S70	A69V	69	Missense	proximal	-1	no	72.205	72.214	EPSD	COSMIC	52.547	Up-regulation
CMGC_CLK_CLK1_ST	P18031	PTPN1	P49759	CLK1	S70	L71M	71	Missense	proximal	1	no	72.205	72.163	EPSD	COSMIC	52.547	Down-regulation
CMGC_CLK_CLK1_ST	P18031	PTPN1	P49759	CLK1	S70	N64I	64	Missense	distal	-6	no	72.205	63.111	EPSD	COSMIC	52.547	Down-regulation
CMGC_CLK_CLK1_ST	P18031	PTPN1	P49759	CLK1	S70	I72T	72	Missense	proximal	2	no	72.205	72.122	EPSD	COSMIC	52.547	Down-regulation
CMGC_CLK_CLK1_ST	P18031	PTPN1	P49759	CLK1	S242	K248T	248	Missense	distal	6	no	93.842	93.604	EPSD;PhosphoSitePlus	COSMIC	52.547	Down-regulation
CMGC_CLK_CLK1_ST	P18031	PTPN1	P49759	CLK1	S243	K248T	248	Missense	distal	5	no	103.093	101.942	PhosphoSitePlus;EPSD	COSMIC	52.547	Down-regulation
CMGC_CLK_CLK1_ST	P18031	PTPN1	P49759	CLK1	S295	L299M	299	Missense	distal	4	no	61.298	60.192	EPSD	COSMIC	52.547	Down-regulation
CMGC_CLK_CLK1_ST	P18031	PTPN1	P49759	CLK1	S295	E300K	300	Missense	distal	5	no	61.298	64.140	EPSD	COSMIC	52.547	Up-regulation
CAMK_CAMKL_BRSK_BRSK2_ST	Q13131	PRKAA1	Q8IWQ3	BRSK2	S502	R505G	505	Missense	distal	3	no	3.087	3.185	EPSD	COSMIC	3.184	Gain
CAMK_CAMKL_BRSK_BRSK2_ST	Q13131	PRKAA1	Q8IWQ3	BRSK2	S517	S524F	524	Missense	distal	7	no	3.417	3.392	EPSD	COSMIC	3.184	Down-regulation
CAMK_CAMKL_BRSK_BRSK2_ST	P52565	ARHGDIA	Q8IWQ3	BRSK2	S47	E40K	40	Missense	distal	-7	no	2.543	3.298	EPSD	COSMIC	3.184	Gain
CAMK_CAMKL_BRSK_BRSK2_ST	P49815	TSC2	Q8IWQ3	BRSK2	S946	E942K	942	Missense	distal	-4	no	4.455	5.024	EPSD	COSMIC	3.184	Up-regulation
CAMK_CAMKL_BRSK_BRSK2_ST	P49815	TSC2	Q8IWQ3	BRSK2	S946	K945E	945	Missense	proximal	-1	no	4.455	4.706	EPSD	COSMIC	3.184	Up-regulation
CAMK_CAMKL_BRSK_BRSK2_ST	P49815	TSC2	Q8IWQ3	BRSK2	S946	S946I	946	Missense	central	0	yes	4.455	0.000	EPSD	COSMIC	3.184	Loss
CAMK_CAMKL_BRSK_BRSK2_ST	P49815	TSC2	Q8IWQ3	BRSK2	T993	R988Q	988	Missense	distal	-5	no	3.697	3.722	EPSD	COSMIC	3.184	Up-regulation
CAMK_CAMKL_BRSK_BRSK2_ST	P49815	TSC2	Q8IWQ3	BRSK2	T993	T993M	993	Missense	central	0	yes	3.697	0.000	EPSD	COSMIC	3.184	Loss
CAMK_CAMKL_BRSK_BRSK2_ST	P49815	TSC2	Q8IWQ3	BRSK2	T993	S999T	999	Missense	distal	6	no	3.697	3.559	EPSD	COSMIC	3.184	Down-regulation
CAMK_CAMKL_BRSK_BRSK2_ST	P49815	TSC2	Q8IWQ3	BRSK2	T993	S999L	999	Missense	distal	6	no	3.697	3.458	EPSD	COSMIC	3.184	Down-regulation
CAMK_CAMKL_BRSK_BRSK2_ST	P49815	TSC2	Q8IWQ3	BRSK2	T993	V987A	987	Missense	distal	-6	no	3.697	3.736	EPSD	COSMIC	3.184	Up-regulation
CAMK_CAMKL_BRSK_BRSK2_ST	P49815	TSC2	Q8IWQ3	BRSK2	T993	S999P	999	Missense	distal	6	no	3.697	3.479	EPSD	COSMIC	3.184	Down-regulation
CAMK_CAMKL_BRSK_BRSK2_ST	P49815	TSC2	Q8IWQ3	BRSK2	S997	S1002L	1002	Missense	distal	5	no	4.377	4.575	EPSD	COSMIC	3.184	Up-regulation
CAMK_CAMKL_BRSK_BRSK2_ST	P49815	TSC2	Q8IWQ3	BRSK2	S997	T993M	993	Missense	distal	-4	no	4.377	4.318	EPSD	COSMIC	3.184	Down-regulation
CAMK_CAMKL_BRSK_BRSK2_ST	P49815	TSC2	Q8IWQ3	BRSK2	S997	S999T	999	Missense	proximal	2	no	4.377	4.376	EPSD	COSMIC	3.184	Down-regulation
CAMK_CAMKL_BRSK_BRSK2_ST	P49815	TSC2	Q8IWQ3	BRSK2	S997	S999L	999	Missense	proximal	2	no	4.377	4.374	EPSD	COSMIC	3.184	Down-regulation
CAMK_CAMKL_BRSK_BRSK2_ST	P49815	TSC2	Q8IWQ3	BRSK2	S997	S999P	999	Missense	proximal	2	no	4.377	4.376	EPSD	COSMIC	3.184	Down-regulation
CAMK_CAMKL_BRSK_BRSK2_ST	P49815	TSC2	Q8IWQ3	BRSK2	S1002	S1002L	1002	Missense	central	0	yes	4.017	0.000	EPSD	COSMIC	3.184	Loss
CAMK_CAMKL_BRSK_BRSK2_ST	P49815	TSC2	Q8IWQ3	BRSK2	S1002	V1008M	1008	Missense	distal	6	no	4.017	4.080	EPSD	COSMIC;CCLE	3.184	Up-regulation
CAMK_CAMKL_BRSK_BRSK2_ST	P49815	TSC2	Q8IWQ3	BRSK2	S1002	S999T	999	Missense	distal	-3	no	4.017	3.842	EPSD	COSMIC	3.184	Down-regulation
CAMK_CAMKL_BRSK_BRSK2_ST	P49815	TSC2	Q8IWQ3	BRSK2	S1002	S999L	999	Missense	distal	-3	no	4.017	3.860	EPSD	COSMIC	3.184	Down-regulation
CAMK_CAMKL_BRSK_BRSK2_ST	P49815	TSC2	Q8IWQ3	BRSK2	S1002	S999P	999	Missense	distal	-3	no	4.017	3.865	EPSD	COSMIC	3.184	Down-regulation
CAMK_CAMKL_BRSK_BRSK2_ST	P49815	TSC2	Q8IWQ3	BRSK2	S1097	S1094L	1094	Missense	distal	-3	no	3.312	3.155	EPSD	COSMIC	3.184	Loss
CAMK_CAMKL_BRSK_BRSK2_ST	P49815	TSC2	Q8IWQ3	BRSK2	S1097	G1099W	1099	Missense	proximal	2	no	3.312	3.311	EPSD	COSMIC	3.184	Down-regulation
CAMK_CAMKL_BRSK_BRSK2_ST	P49815	TSC2	Q8IWQ3	BRSK2	S1097	E1093K	1093	Missense	distal	-4	no	3.312	3.881	EPSD	COSMIC	3.184	Up-regulation
CAMK_CAMKL_BRSK_BRSK2_ST	P49815	TSC2	Q8IWQ3	BRSK2	S1097	S1095I	1095	Missense	proximal	-2	no	3.312	3.308	EPSD	COSMIC	3.184	Down-regulation
CAMK_CAMKL_BRSK_BRSK2_ST	P49815	TSC2	Q8IWQ3	BRSK2	S1097	S1097C	1097	Missense	central	0	yes	3.312	0.000	EPSD	COSMIC	3.184	Loss
CAMK_CAMKL_BRSK_BRSK2_ST	P49815	TSC2	Q8IWQ3	BRSK2	S1338	S1334C	1334	Missense	distal	-4	no	4.897	4.321	EPSD	COSMIC	3.184	Down-regulation
CAMK_CAMKL_BRSK_BRSK2_ST	P49815	TSC2	Q8IWQ3	BRSK2	S1338	S1341F	1341	Missense	distal	3	no	4.897	5.150	EPSD	COSMIC	3.184	Up-regulation
CAMK_CAMKL_BRSK_BRSK2_ST	P49815	TSC2	Q8IWQ3	BRSK2	S1338	A1332V	1332	Missense	distal	-6	no	4.897	4.858	EPSD	COSMIC	3.184	Down-regulation
CAMK_CAMKL_BRSK_BRSK2_ST	P49815	TSC2	Q8IWQ3	BRSK2	S1338	E1344D	1344	Missense	distal	6	no	4.897	4.940	EPSD	COSMIC	3.184	Up-regulation
CAMK_CAMKL_BRSK_BRSK2_ST	P49815	TSC2	Q8IWQ3	BRSK2	S1338	S1334R	1334	Missense	distal	-4	no	4.897	4.171	EPSD	COSMIC	3.184	Down-regulation
CAMK_CAMKL_BRSK_BRSK2_ST	P49815	TSC2	Q8IWQ3	BRSK2	S1338	R1335Q	1335	Missense	distal	-3	no	4.897	4.256	EPSD	COSMIC	3.184	Down-regulation
CAMK_CAMKL_BRSK_BRSK2_ST	P49815	TSC2	Q8IWQ3	BRSK2	S1341	S1334C	1334	Missense	distal	-7	no	4.517	3.542	EPSD	COSMIC	3.184	Down-regulation
CAMK_CAMKL_BRSK_BRSK2_ST	P49815	TSC2	Q8IWQ3	BRSK2	S1341	S1341F	1341	Missense	central	0	yes	4.517	0.000	EPSD	COSMIC	3.184	Loss
CAMK_CAMKL_BRSK_BRSK2_ST	P49815	TSC2	Q8IWQ3	BRSK2	S1341	E1344D	1344	Missense	distal	3	no	4.517	4.313	EPSD	COSMIC	3.184	Down-regulation
CAMK_CAMKL_BRSK_BRSK2_ST	P49815	TSC2	Q8IWQ3	BRSK2	S1341	S1334R	1334	Missense	distal	-7	no	4.517	3.854	EPSD	COSMIC	3.184	Down-regulation
CAMK_CAMKL_BRSK_BRSK2_ST	P49815	TSC2	Q8IWQ3	BRSK2	S1341	S1346C	1346	Missense	distal	5	no	4.517	4.546	EPSD	COSMIC	3.184	Up-regulation
CAMK_CAMKL_BRSK_BRSK2_ST	P49815	TSC2	Q8IWQ3	BRSK2	S1341	R1335Q	1335	Missense	distal	-6	no	4.517	4.499	EPSD	COSMIC	3.184	Down-regulation
CAMK_CAMKL_BRSK_BRSK2_ST	P49815	TSC2	Q8IWQ3	BRSK2	S1379	S1383C	1383	Missense	distal	4	no	3.716	3.762	EPSD	COSMIC	3.184	Up-regulation
CAMK_CAMKL_BRSK_BRSK2_ST	P49815	TSC2	Q8IWQ3	BRSK2	S1379	S1383N	1383	Missense	distal	4	no	3.716	3.883	EPSD	COSMIC	3.184	Up-regulation
CAMK_CAMKL_BRSK_BRSK2_ST	P49815	TSC2	Q8IWQ3	BRSK2	S1379	S1383R	1383	Missense	distal	4	no	3.716	3.767	EPSD	COSMIC	3.184	Up-regulation
CAMK_CAMKL_BRSK_BRSK2_ST	P49815	TSC2	Q8IWQ3	BRSK2	S1379	S1379L	1379	Missense	central	0	yes	3.716	0.000	EPSD	COSMIC	3.184	Loss
CAMK_CAMKL_BRSK_BRSK2_ST	P49815	TSC2	Q8IWQ3	BRSK2	S1379	S1385F	1385	Missense	distal	6	no	3.716	3.557	EPSD	COSMIC	3.184	Down-regulation
CAMK_CAMKL_BRSK_BRSK2_ST	P49815	TSC2	Q8IWQ3	BRSK2	S1379	S1375L	1375	Missense	distal	-4	no	3.716	3.030	EPSD	COSMIC	3.184	Loss
CAMK_CAMKL_BRSK_BRSK2_ST	P49815	TSC2	Q8IWQ3	BRSK2	S1383	S1383C	1383	Missense	central	0	yes	3.458	0.000	EPSD	COSMIC	3.184	Loss
CAMK_CAMKL_BRSK_BRSK2_ST	P49815	TSC2	Q8IWQ3	BRSK2	S1383	S1383N	1383	Missense	central	0	yes	3.458	0.000	EPSD	COSMIC	3.184	Loss
CAMK_CAMKL_BRSK_BRSK2_ST	P49815	TSC2	Q8IWQ3	BRSK2	S1383	S1387L	1387	Missense	distal	4	no	3.458	3.713	EPSD	COSMIC	3.184	Up-regulation
CAMK_CAMKL_BRSK_BRSK2_ST	P49815	TSC2	Q8IWQ3	BRSK2	S1383	S1383R	1383	Missense	central	0	yes	3.458	0.000	EPSD	COSMIC	3.184	Loss
CAMK_CAMKL_BRSK_BRSK2_ST	P49815	TSC2	Q8IWQ3	BRSK2	S1383	S1379L	1379	Missense	distal	-4	no	3.458	2.772	EPSD	COSMIC	3.184	Loss
CAMK_CAMKL_BRSK_BRSK2_ST	P49815	TSC2	Q8IWQ3	BRSK2	S1383	E1390G	1390	Missense	distal	7	no	3.458	3.471	EPSD	COSMIC	3.184	Up-regulation
CAMK_CAMKL_BRSK_BRSK2_ST	P49815	TSC2	Q8IWQ3	BRSK2	S1383	P1389H	1389	Missense	distal	6	no	3.458	3.582	EPSD	COSMIC	3.184	Up-regulation
CAMK_CAMKL_BRSK_BRSK2_ST	P49815	TSC2	Q8IWQ3	BRSK2	S1383	S1385F	1385	Missense	proximal	2	no	3.458	3.457	EPSD	COSMIC	3.184	Down-regulation
CAMK_CAMKL_BRSK_BRSK2_ST	P49815	TSC2	Q8IWQ3	BRSK2	S1383	E1390D	1390	Missense	distal	7	no	3.458	3.428	EPSD	COSMIC	3.184	Down-regulation
CAMK_CAMKL_BRSK_BRSK2_ST	P49815	TSC2	Q8IWQ3	BRSK2	S1386	S1383R	1383	Missense	distal	-3	no	2.722	3.491	EPSD	COSMIC	3.184	Gain
CAMK_CAMKL_BRSK_BRSK2_ST	P49815	TSC2	Q8IWQ3	BRSK2	S1387	S1383C	1383	Missense	distal	-4	no	9.939	9.363	PhosphoSitePlus	COSMIC	3.184	Down-regulation
CAMK_CAMKL_BRSK_BRSK2_ST	P49815	TSC2	Q8IWQ3	BRSK2	S1387	S1383N	1383	Missense	distal	-4	no	9.939	10.432	PhosphoSitePlus	COSMIC	3.184	Up-regulation
CAMK_CAMKL_BRSK_BRSK2_ST	P49815	TSC2	Q8IWQ3	BRSK2	S1387	S1387L	1387	Missense	central	0	yes	9.939	0.000	PhosphoSitePlus	COSMIC	3.184	Loss
CAMK_CAMKL_BRSK_BRSK2_ST	P49815	TSC2	Q8IWQ3	BRSK2	S1387	S1383R	1383	Missense	distal	-4	no	9.939	9.213	PhosphoSitePlus	COSMIC	3.184	Down-regulation
CAMK_CAMKL_BRSK_BRSK2_ST	P49815	TSC2	Q8IWQ3	BRSK2	S1387	E1390G	1390	Missense	distal	3	no	9.939	10.058	PhosphoSitePlus	COSMIC	3.184	Up-regulation
CAMK_CAMKL_BRSK_BRSK2_ST	P49815	TSC2	Q8IWQ3	BRSK2	S1387	S1385F	1385	Missense	proximal	-2	no	9.939	9.926	PhosphoSitePlus	COSMIC	3.184	Down-regulation
CAMK_CAMKL_BRSK_BRSK2_ST	P49815	TSC2	Q8IWQ3	BRSK2	S1387	E1390D	1390	Missense	distal	3	no	9.939	9.735	PhosphoSitePlus	COSMIC	3.184	Down-regulation
CAMK_CAMKL_BRSK_BRSK2_ST	P49815	TSC2	Q8IWQ3	BRSK2	T1393	P1389H	1389	Missense	distal	-4	no	3.141	3.212	EPSD	COSMIC	3.184	Gain
CAMK_CAMKL_BRSK_BRSK2_ST	P49815	TSC2	Q8IWQ3	BRSK2	S1420	E1413D	1413	Missense	distal	-7	no	2.713	3.281	EPSD	COSMIC	3.184	Gain
CAMK_CAMKL_BRSK_BRSK2_ST	P49815	TSC2	Q8IWQ3	BRSK2	T1462	S1464F	1464	Missense	proximal	2	no	3.574	3.573	EPSD	COSMIC	3.184	Down-regulation
CAMK_CAMKL_BRSK_BRSK2_ST	P49815	TSC2	Q8IWQ3	BRSK2	T1462	S1464Y	1464	Missense	proximal	2	no	3.574	3.573	EPSD	COSMIC	3.184	Down-regulation
CAMK_CAMKL_BRSK_BRSK2_ST	P49815	TSC2	Q8IWQ3	BRSK2	T1462	Y1461H	1461	Missense	proximal	-1	no	3.574	3.604	EPSD	COSMIC	3.184	Up-regulation
CAMK_CAMKL_BRSK_BRSK2_ST	P49815	TSC2	Q8IWQ3	BRSK2	T1462	R1459Q	1459	Missense	distal	-3	no	3.574	2.934	EPSD	COSMIC	3.184	Loss
CAMK_CAMKL_BRSK_BRSK2_ST	P49815	TSC2	Q8IWQ3	BRSK2	T1462	I1463N	1463	Missense	proximal	1	no	3.574	3.980	EPSD	COSMIC	3.184	Up-regulation
CAMK_CAMKL_BRSK_BRSK2_ST	P49815	TSC2	Q8IWQ3	BRSK2	T1462	D1465N	1465	Missense	distal	3	no	3.574	3.724	EPSD	COSMIC	3.184	Up-regulation
CAMK_CAMKL_BRSK_BRSK2_ST	P49815	TSC2	Q8IWQ3	BRSK2	T1462	P1468T	1468	Missense	distal	6	no	3.574	3.654	EPSD	COSMIC	3.184	Up-regulation
CAMK_CAMKL_BRSK_BRSK2_ST	P49815	TSC2	Q8IWQ3	BRSK2	T1462	T1462I	1462	Missense	central	0	yes	3.574	0.000	EPSD	COSMIC	3.184	Loss
CAMK_CAMKL_BRSK_BRSK2_ST	P49815	TSC2	Q8IWQ3	BRSK2	T1462	S1464C	1464	Missense	proximal	2	no	3.574	3.573	EPSD	COSMIC	3.184	Down-regulation
CAMK_CAMKL_BRSK_BRSK2_ST	P49815	TSC2	Q8IWQ3	BRSK2	T1697	D1690N	1690	Missense	distal	-7	no	2.912	3.213	EPSD	COSMIC	3.184	Gain
CAMK_CAMKL_BRSK_BRSK2_ST	P49815	TSC2	Q8IWQ3	BRSK2	S1730	R1729C	1729	Missense	proximal	-1	no	4.765	4.434	EPSD	COSMIC	3.184	Down-regulation
CAMK_CAMKL_BRSK_BRSK2_ST	P49815	TSC2	Q8IWQ3	BRSK2	S1730	R1729H	1729	Missense	proximal	-1	no	4.765	4.558	EPSD	COSMIC	3.184	Down-regulation
CAMK_CAMKL_BRSK_BRSK2_ST	P49815	TSC2	Q8IWQ3	BRSK2	S1730	P1737L	1737	Missense	distal	7	no	4.765	4.728	EPSD	COSMIC	3.184	Down-regulation
CAMK_CAMKL_BRSK_BRSK2_ST	P49815	TSC2	Q8IWQ3	BRSK2	S1730	T1733A	1733	Missense	distal	3	no	4.765	4.871	EPSD	COSMIC	3.184	Up-regulation
CAMK_CAMKL_BRSK_BRSK2_ST	P49815	TSC2	Q8IWQ3	BRSK2	S1730	H1726N	1726	Missense	distal	-4	no	4.765	5.763	EPSD	COSMIC	3.184	Up-regulation
CAMK_CAMKL_BRSK_BRSK2_ST	P49815	TSC2	Q8IWQ3	BRSK2	S1730	R1729S	1729	Missense	proximal	-1	no	4.765	4.800	EPSD	COSMIC	3.184	Up-regulation
CAMK_CAMKL_BRSK_BRSK2_ST	P49815	TSC2	Q8IWQ3	BRSK2	S1730	S1730F	1730	Missense	central	0	yes	4.765	0.000	EPSD	COSMIC	3.184	Loss
CAMK_CAMKL_BRSK_BRSK2_ST	P49815	TSC2	Q8IWQ3	BRSK2	S1730	S1730C	1730	Missense	central	0	yes	4.765	0.000	EPSD	COSMIC	3.184	Loss
CAMK_CAMKL_BRSK_BRSK2_ST	P49815	TSC2	Q8IWQ3	BRSK2	S1730	S1728P	1728	Missense	proximal	-2	no	4.765	4.746	EPSD	COSMIC	3.184	Down-regulation
CAMK_CAMKL_BRSK_BRSK2_ST	P49815	TSC2	Q8IWQ3	BRSK2	S1730	P1732S	1732	Missense	proximal	2	no	4.765	4.766	EPSD	COSMIC	3.184	Up-regulation
CAMK_CAMKL_BRSK_BRSK2_ST	Q00536	CDK16	Q8IWQ3	BRSK2	S12	R9W	9	Missense	distal	-3	no	6.450	5.577	PhosphoSitePlus	COSMIC	3.184	Down-regulation
CAMK_CAMKL_BRSK_BRSK2_ST	Q00536	CDK16	Q8IWQ3	BRSK2	S12	R19Q	19	Missense	distal	7	no	6.450	6.442	PhosphoSitePlus	COSMIC	3.184	Down-regulation
CAMK_CAMKL_BRSK_BRSK2_ST	Q00536	CDK16	Q8IWQ3	BRSK2	S12	R9Q	9	Missense	distal	-3	no	6.450	5.810	PhosphoSitePlus	COSMIC	3.184	Down-regulation
CAMK_CAMKL_BRSK_BRSK2_ST	Q00536	CDK16	Q8IWQ3	BRSK2	S12	R16C	16	Missense	distal	4	no	6.450	6.445	PhosphoSitePlus	COSMIC	3.184	Down-regulation
CAMK_CAMKL_BRSK_BRSK2_ST	Q00536	CDK16	Q8IWQ3	BRSK2	S58	R57C	57	Missense	proximal	-1	no	4.691	4.360	EPSD	COSMIC	3.184	Down-regulation
CAMK_CAMKL_BRSK_BRSK2_ST	Q00536	CDK16	Q8IWQ3	BRSK2	S58	P62L	62	Missense	distal	4	no	4.691	4.917	EPSD	COSMIC	3.184	Up-regulation
CAMK_CAMKL_BRSK_BRSK2_ST	Q00536	CDK16	Q8IWQ3	BRSK2	S65	P62L	62	Missense	distal	-3	no	4.297	4.292	EPSD	COSMIC	3.184	Down-regulation
CAMK_CAMKL_BRSK_BRSK2_ST	Q00536	CDK16	Q8IWQ3	BRSK2	S65	E72D	72	Missense	distal	7	no	4.297	4.267	EPSD	COSMIC	3.184	Down-regulation
CAMK_CAMKL_BRSK_BRSK2_ST	Q00536	CDK16	Q8IWQ3	BRSK2	S82	G77W	77	Missense	distal	-5	no	3.270	3.199	EPSD	COSMIC	3.184	Down-regulation
CAMK_CAMKL_BRSK_BRSK2_ST	Q00536	CDK16	Q8IWQ3	BRSK2	S82	S86L	86	Missense	distal	4	no	3.270	3.526	EPSD	COSMIC	3.184	Up-regulation
CAMK_CAMKL_BRSK_BRSK2_ST	Q00536	CDK16	Q8IWQ3	BRSK2	S82	D79A	79	Missense	distal	-3	no	3.270	3.306	EPSD	COSMIC	3.184	Up-regulation
CAMK_CAMKL_BRSK_BRSK2_ST	Q00536	CDK16	Q8IWQ3	BRSK2	S89	P96T	96	Missense	distal	7	no	3.594	3.572	EPSD	COSMIC	3.184	Down-regulation
CAMK_CAMKL_BRSK_BRSK2_ST	Q00536	CDK16	Q8IWQ3	BRSK2	S89	S86L	86	Missense	distal	-3	no	3.594	3.438	EPSD	COSMIC	3.184	Down-regulation
CAMK_CAMKL_BRSK_BRSK2_ST	Q00536	CDK16	Q8IWQ3	BRSK2	S119	L118I	118	Missense	proximal	-1	no	3.775	3.599	EPSD	COSMIC	3.184	Down-regulation
CAMK_CAMKL_BRSK_BRSK2_ST	Q00536	CDK16	Q8IWQ3	BRSK2	S119	E112K	112	Missense	distal	-7	no	3.775	4.530	EPSD	COSMIC	3.184	Up-regulation
CAMK_CAMKL_BRSK_BRSK2_ST	Q00536	CDK16	Q8IWQ3	BRSK2	S119	R125W	125	Missense	distal	6	no	3.775	3.822	EPSD	COSMIC	3.184	Up-regulation
CAMK_CAMKL_BRSK_BRSK2_ST	Q00536	CDK16	Q8IWQ3	BRSK2	S119	R117C	117	Missense	proximal	-2	no	3.775	3.808	EPSD	COSMIC	3.184	Up-regulation
CAMK_CAMKL_BRSK_BRSK2_ST	Q00536	CDK16	Q8IWQ3	BRSK2	S119	R117H	117	Missense	proximal	-2	no	3.775	3.816	EPSD	COSMIC	3.184	Up-regulation
CAMK_CAMKL_BRSK_BRSK2_ST	Q00536	CDK16	Q8IWQ3	BRSK2	S153	R150C	150	Missense	distal	-3	no	4.334	3.425	EPSD	COSMIC	3.184	Down-regulation
CAMK_CAMKL_BRSK_BRSK2_ST	Q00536	CDK16	Q8IWQ3	BRSK2	S153	R150H	150	Missense	distal	-3	no	4.334	3.430	EPSD	COSMIC	3.184	Down-regulation
CAMK_CAMKL_BRSK_BRSK2_ST	Q00536	CDK16	Q8IWQ3	BRSK2	S319	S319F	319	Missense	central	0	yes	3.726	0.000	EPSD	COSMIC	3.184	Loss
CAMK_CAMKL_BRSK_BRSK2_ST	Q00536	CDK16	Q8IWQ3	BRSK2	S319	W326L	326	Missense	distal	7	no	3.726	3.732	EPSD	COSMIC	3.184	Up-regulation
CAMK_CAMKL_BRSK_BRSK2_ST	Q00536	CDK16	Q8IWQ3	BRSK2	S319	V322A	322	Missense	distal	3	no	3.726	3.853	EPSD	COSMIC	3.184	Up-regulation
CAMK_CAMKL_BRSK_BRSK2_ST	Q00536	CDK16	Q8IWQ3	BRSK2	S319	W326R	326	Missense	distal	7	no	3.726	3.748	EPSD	COSMIC	3.184	Up-regulation
Atypical_PIKK_DNAPK_PRKDC_ST	P78527	PRKDC	P78527	PRKDC	S20	Q16K	16	Missense	distal	-4	no	9.615	9.214	EPSD	COSMIC	8.283	Down-regulation
Atypical_PIKK_DNAPK_PRKDC_ST	P78527	PRKDC	P78527	PRKDC	S20	A27S	27	Missense	distal	7	no	9.615	9.846	EPSD	COSMIC	8.283	Up-regulation
Atypical_PIKK_DNAPK_PRKDC_ST	P78527	PRKDC	P78527	PRKDC	S694	L691P	691	Missense	distal	-3	no	11.583	11.783	EPSD	COSMIC	8.283	Up-regulation
Atypical_PIKK_DNAPK_PRKDC_ST	P78527	PRKDC	P78527	PRKDC	S842	L848F	848	Missense	distal	6	no	8.604	8.609	EPSD	COSMIC	8.283	Up-regulation
Atypical_PIKK_DNAPK_PRKDC_ST	P78527	PRKDC	P78527	PRKDC	S875	S876L	876	Missense	proximal	1	no	5.777	10.071	EPSD	COSMIC	8.283	Gain
Atypical_PIKK_DNAPK_PRKDC_ST	P78527	PRKDC	P78527	PRKDC	S882	M879T	879	Missense	distal	-3	no	8.862	9.005	EPSD	COSMIC	8.283	Up-regulation
Atypical_PIKK_DNAPK_PRKDC_ST	P78527	PRKDC	P78527	PRKDC	S882	S876L	876	Missense	distal	-6	no	8.862	8.617	EPSD	COSMIC	8.283	Down-regulation
Atypical_PIKK_DNAPK_PRKDC_ST	P78527	PRKDC	P78527	PRKDC	T946	T946M	946	Missense	central	0	yes	11.193	0.000	EPSD	COSMIC	8.283	Loss
Atypical_PIKK_DNAPK_PRKDC_ST	P78527	PRKDC	P78527	PRKDC	S1546	Q1547H	1547	Missense	proximal	1	no	12.221	1.886	EPSD	COSMIC	8.283	Loss
Atypical_PIKK_DNAPK_PRKDC_ST	P78527	PRKDC	P78527	PRKDC	S1546	G1544D	1544	Missense	proximal	-2	no	12.221	12.105	EPSD	COSMIC	8.283	Down-regulation
Atypical_PIKK_DNAPK_PRKDC_ST	P78527	PRKDC	P78527	PRKDC	S1546	V1550I	1550	Missense	distal	4	no	12.221	12.197	EPSD	COSMIC	8.283	Down-regulation
Atypical_PIKK_DNAPK_PRKDC_ST	P78527	PRKDC	P78527	PRKDC	S1546	G1548D	1548	Missense	proximal	2	no	12.221	14.017	EPSD	COSMIC	8.283	Up-regulation
Atypical_PIKK_DNAPK_PRKDC_ST	P78527	PRKDC	P78527	PRKDC	T1733	P1734Q	1734	Missense	proximal	1	no	7.122	11.603	EPSD	COSMIC	8.283	Gain
Atypical_PIKK_DNAPK_PRKDC_ST	P78527	PRKDC	P78527	PRKDC	T1793	R1788K	1788	Missense	distal	-5	no	8.197	8.636	EPSD	COSMIC	8.283	Gain
Atypical_PIKK_DNAPK_PRKDC_ST	P78527	PRKDC	P78527	PRKDC	T1793	R1788S	1788	Missense	distal	-5	no	8.197	8.669	EPSD	COSMIC	8.283	Gain
Atypical_PIKK_DNAPK_PRKDC_ST	P78527	PRKDC	P78527	PRKDC	T1793	G1796S	1796	Missense	distal	3	no	8.197	8.456	EPSD	COSMIC	8.283	Gain
Atypical_PIKK_DNAPK_PRKDC_ST	P78527	PRKDC	P78527	PRKDC	T1865	L1858V	1858	Missense	distal	-7	no	8.438	7.931	EPSD	COSMIC	8.283	Loss
Atypical_PIKK_DNAPK_PRKDC_ST	P78527	PRKDC	P78527	PRKDC	T1865	N1859S	1859	Missense	distal	-6	no	8.438	8.493	EPSD	COSMIC	8.283	Up-regulation
Atypical_PIKK_DNAPK_PRKDC_ST	P78527	PRKDC	P78527	PRKDC	T1865	L1858Q	1858	Missense	distal	-7	no	8.438	9.053	EPSD	COSMIC	8.283	Up-regulation
Atypical_PIKK_DNAPK_PRKDC_ST	P78527	PRKDC	P78527	PRKDC	T1865	D1864Y	1864	Missense	proximal	-1	no	8.438	8.026	EPSD	COSMIC	8.283	Loss
Atypical_PIKK_DNAPK_PRKDC_ST	P78527	PRKDC	P78527	PRKDC	T1865	T1868I	1868	Missense	distal	3	no	8.438	7.817	EPSD	COSMIC	8.283	Loss
Atypical_PIKK_DNAPK_PRKDC_ST	P78527	PRKDC	P78527	PRKDC	T1865	L1858I	1858	Missense	distal	-7	no	8.438	7.349	EPSD	COSMIC	8.283	Loss
Atypical_PIKK_DNAPK_PRKDC_ST	P78527	PRKDC	P78527	PRKDC	S2041	G2048E	2048	Missense	distal	7	no	11.303	12.029	EPSD	COSMIC	8.283	Up-regulation
Atypical_PIKK_DNAPK_PRKDC_ST	P78527	PRKDC	P78527	PRKDC	S2041	M2040I	2040	Missense	proximal	-1	no	11.303	10.791	EPSD	COSMIC	8.283	Down-regulation
Atypical_PIKK_DNAPK_PRKDC_ST	P78527	PRKDC	P78527	PRKDC	S2041	S2046L	2046	Missense	distal	5	no	11.303	11.226	EPSD	COSMIC	8.283	Down-regulation
Atypical_PIKK_DNAPK_PRKDC_ST	P78527	PRKDC	P78527	PRKDC	S2041	S2037I	2037	Missense	distal	-4	no	11.303	10.039	EPSD	COSMIC	8.283	Down-regulation
Atypical_PIKK_DNAPK_PRKDC_ST	P78527	PRKDC	P78527	PRKDC	S2041	G2048A	2048	Missense	distal	7	no	11.303	11.780	EPSD	COSMIC	8.283	Up-regulation
Atypical_PIKK_DNAPK_PRKDC_ST	P78527	PRKDC	P78527	PRKDC	S2041	F2045I	2045	Missense	distal	4	no	11.303	11.255	EPSD	COSMIC	8.283	Down-regulation
Atypical_PIKK_DNAPK_PRKDC_ST	P78527	PRKDC	P78527	PRKDC	S2041	G2048R	2048	Missense	distal	7	no	11.303	10.854	EPSD	COSMIC	8.283	Down-regulation
Atypical_PIKK_DNAPK_PRKDC_ST	P78527	PRKDC	P78527	PRKDC	S2041	Q2042K	2042	Missense	proximal	1	no	11.303	0.098	EPSD	COSMIC	8.283	Loss
Atypical_PIKK_DNAPK_PRKDC_ST	P78527	PRKDC	P78527	PRKDC	S2051	G2048E	2048	Missense	distal	-3	no	11.437	11.717	EPSD	COSMIC	8.283	Up-regulation
Atypical_PIKK_DNAPK_PRKDC_ST	P78527	PRKDC	P78527	PRKDC	S2051	S2046L	2046	Missense	distal	-5	no	11.437	11.078	EPSD	COSMIC	8.283	Down-regulation
Atypical_PIKK_DNAPK_PRKDC_ST	P78527	PRKDC	P78527	PRKDC	S2051	G2048A	2048	Missense	distal	-3	no	11.437	11.529	EPSD	COSMIC	8.283	Up-regulation
Atypical_PIKK_DNAPK_PRKDC_ST	P78527	PRKDC	P78527	PRKDC	S2051	F2045I	2045	Missense	distal	-6	no	11.437	10.701	EPSD	COSMIC	8.283	Down-regulation
Atypical_PIKK_DNAPK_PRKDC_ST	P78527	PRKDC	P78527	PRKDC	S2051	D2058N	2058	Missense	distal	7	no	11.437	10.771	EPSD	COSMIC	8.283	Down-regulation
Atypical_PIKK_DNAPK_PRKDC_ST	P78527	PRKDC	P78527	PRKDC	S2051	S2055R	2055	Missense	distal	4	no	11.437	11.399	EPSD	COSMIC	8.283	Down-regulation
Atypical_PIKK_DNAPK_PRKDC_ST	P78527	PRKDC	P78527	PRKDC	S2051	G2048R	2048	Missense	distal	-3	no	11.437	11.341	EPSD	COSMIC	8.283	Down-regulation
Atypical_PIKK_DNAPK_PRKDC_ST	P78527	PRKDC	P78527	PRKDC	S2053	G2048E	2048	Missense	distal	-5	no	9.623	9.945	EPSD	COSMIC	8.283	Up-regulation
Atypical_PIKK_DNAPK_PRKDC_ST	P78527	PRKDC	P78527	PRKDC	S2053	S2046L	2046	Missense	distal	-7	no	9.623	9.157	EPSD	COSMIC	8.283	Down-regulation
Atypical_PIKK_DNAPK_PRKDC_ST	P78527	PRKDC	P78527	PRKDC	S2053	P2059A	2059	Missense	distal	6	no	9.623	9.614	EPSD	COSMIC	8.283	Down-regulation
Atypical_PIKK_DNAPK_PRKDC_ST	P78527	PRKDC	P78527	PRKDC	S2053	G2048A	2048	Missense	distal	-5	no	9.623	9.790	EPSD	COSMIC	8.283	Up-regulation
Atypical_PIKK_DNAPK_PRKDC_ST	P78527	PRKDC	P78527	PRKDC	S2053	D2058N	2058	Missense	distal	5	no	9.623	9.473	EPSD	COSMIC	8.283	Down-regulation
Atypical_PIKK_DNAPK_PRKDC_ST	P78527	PRKDC	P78527	PRKDC	S2053	S2055R	2055	Missense	proximal	2	no	9.623	8.348	EPSD	COSMIC	8.283	Down-regulation
Atypical_PIKK_DNAPK_PRKDC_ST	P78527	PRKDC	P78527	PRKDC	S2053	G2048R	2048	Missense	distal	-5	no	9.623	9.453	EPSD	COSMIC	8.283	Down-regulation
Atypical_PIKK_DNAPK_PRKDC_ST	P78527	PRKDC	P78527	PRKDC	S2056	A2062T	2062	Missense	distal	6	no	13.176	13.171	EPSD;PhosphoSitePlus	COSMIC	8.283	Down-regulation
Atypical_PIKK_DNAPK_PRKDC_ST	P78527	PRKDC	P78527	PRKDC	S2056	P2059A	2059	Missense	distal	3	no	13.176	13.158	EPSD;PhosphoSitePlus	COSMIC	8.283	Down-regulation
Atypical_PIKK_DNAPK_PRKDC_ST	P78527	PRKDC	P78527	PRKDC	S2056	D2058N	2058	Missense	proximal	2	no	13.176	11.233	EPSD;PhosphoSitePlus	COSMIC	8.283	Down-regulation
Atypical_PIKK_DNAPK_PRKDC_ST	P78527	PRKDC	P78527	PRKDC	S2056	S2055R	2055	Missense	proximal	-1	no	13.176	12.434	EPSD;PhosphoSitePlus	COSMIC	8.283	Down-regulation
Atypical_PIKK_DNAPK_PRKDC_ST	P78527	PRKDC	P78527	PRKDC	T2535	R2538W	2538	Missense	distal	3	no	9.268	9.131	EPSD	COSMIC	8.283	Down-regulation
Atypical_PIKK_DNAPK_PRKDC_ST	P78527	PRKDC	P78527	PRKDC	T2535	R2530M	2530	Missense	distal	-5	no	9.268	9.270	EPSD	COSMIC	8.283	Up-regulation
Atypical_PIKK_DNAPK_PRKDC_ST	P78527	PRKDC	P78527	PRKDC	T2535	L2542V	2542	Missense	distal	7	no	9.268	8.701	EPSD	COSMIC	8.283	Down-regulation
Atypical_PIKK_DNAPK_PRKDC_ST	P78527	PRKDC	P78527	PRKDC	T2609	L2616V	2616	Missense	distal	7	no	12.466	11.900	PhosphoSitePlus;EPSD	COSMIC	8.283	Down-regulation
Atypical_PIKK_DNAPK_PRKDC_ST	P78527	PRKDC	P78527	PRKDC	T2609	M2605I	2605	Missense	distal	-4	no	12.466	11.926	PhosphoSitePlus;EPSD	COSMIC	8.283	Down-regulation
Atypical_PIKK_DNAPK_PRKDC_ST	P78527	PRKDC	P78527	PRKDC	T2609	L2602F	2602	Missense	distal	-7	no	12.466	12.388	PhosphoSitePlus;EPSD	COSMIC	8.283	Down-regulation
Atypical_PIKK_DNAPK_PRKDC_ST	P78527	PRKDC	P78527	PRKDC	S2612	L2616V	2616	Missense	distal	4	no	10.972	10.944	EPSD;PhosphoSitePlus	COSMIC	8.283	Down-regulation
Atypical_PIKK_DNAPK_PRKDC_ST	P78527	PRKDC	P78527	PRKDC	S2612	M2605I	2605	Missense	distal	-7	no	10.972	10.062	EPSD;PhosphoSitePlus	COSMIC	8.283	Down-regulation
Atypical_PIKK_DNAPK_PRKDC_ST	P78527	PRKDC	P78527	PRKDC	S2612	T2618I	2618	Missense	distal	6	no	10.972	10.941	EPSD;PhosphoSitePlus	COSMIC	8.283	Down-regulation
Atypical_PIKK_DNAPK_PRKDC_ST	P78527	PRKDC	P78527	PRKDC	S2612	R2619H	2619	Missense	distal	7	no	10.972	12.153	EPSD;PhosphoSitePlus	COSMIC	8.283	Up-regulation
Atypical_PIKK_DNAPK_PRKDC_ST	P78527	PRKDC	P78527	PRKDC	T2615	T2620N	2620	Missense	distal	5	no	9.109	9.177	EPSD	COSMIC	8.283	Up-regulation
Atypical_PIKK_DNAPK_PRKDC_ST	P78527	PRKDC	P78527	PRKDC	T2615	L2616V	2616	Missense	proximal	1	no	9.109	7.610	EPSD	COSMIC	8.283	Loss
Atypical_PIKK_DNAPK_PRKDC_ST	P78527	PRKDC	P78527	PRKDC	T2615	T2618I	2618	Missense	distal	3	no	9.109	8.487	EPSD	COSMIC	8.283	Down-regulation
Atypical_PIKK_DNAPK_PRKDC_ST	P78527	PRKDC	P78527	PRKDC	T2615	R2619H	2619	Missense	distal	4	no	9.109	9.130	EPSD	COSMIC	8.283	Up-regulation
Atypical_PIKK_DNAPK_PRKDC_ST	P78527	PRKDC	P78527	PRKDC	T2620	T2620N	2620	Missense	central	0	yes	13.138	0.000	EPSD	COSMIC	8.283	Loss
Atypical_PIKK_DNAPK_PRKDC_ST	P78527	PRKDC	P78527	PRKDC	T2620	L2616V	2616	Missense	distal	-4	no	13.138	12.757	EPSD	COSMIC	8.283	Down-regulation
Atypical_PIKK_DNAPK_PRKDC_ST	P78527	PRKDC	P78527	PRKDC	T2620	T2618I	2618	Missense	proximal	-2	no	13.138	13.324	EPSD	COSMIC	8.283	Up-regulation
Atypical_PIKK_DNAPK_PRKDC_ST	P78527	PRKDC	P78527	PRKDC	T2620	R2619H	2619	Missense	proximal	-1	no	13.138	14.191	EPSD	COSMIC	8.283	Up-regulation
Atypical_PIKK_DNAPK_PRKDC_ST	P78527	PRKDC	P78527	PRKDC	T2620	S2626L	2626	Missense	distal	6	no	13.138	13.137	EPSD	COSMIC	8.283	Down-regulation
Atypical_PIKK_DNAPK_PRKDC_ST	P78527	PRKDC	P78527	PRKDC	T2638	R2636M	2636	Missense	proximal	-2	no	12.584	12.592	EPSD;PhosphoSitePlus	COSMIC	8.283	Up-regulation
Atypical_PIKK_DNAPK_PRKDC_ST	P78527	PRKDC	P78527	PRKDC	T2647	R2653T	2653	Missense	distal	6	no	10.806	10.821	EPSD;PhosphoSitePlus	COSMIC	8.283	Up-regulation
Atypical_PIKK_DNAPK_PRKDC_ST	P78527	PRKDC	P78527	PRKDC	S2655	G2661R	2661	Missense	distal	6	no	9.091	9.080	EPSD	COSMIC	8.283	Down-regulation
Atypical_PIKK_DNAPK_PRKDC_ST	P78527	PRKDC	P78527	PRKDC	S2655	R2653T	2653	Missense	proximal	-2	no	9.091	9.034	EPSD	COSMIC	8.283	Down-regulation
Atypical_PIKK_DNAPK_PRKDC_ST	P78527	PRKDC	P78527	PRKDC	S2672	V2668G	2668	Missense	distal	-4	no	8.161	8.542	EPSD	COSMIC	8.283	Gain
Atypical_PIKK_DNAPK_PRKDC_ST	P78527	PRKDC	P78527	PRKDC	S2677	H2682L	2682	Missense	distal	5	no	8.891	8.868	EPSD	COSMIC	8.283	Down-regulation
Atypical_PIKK_DNAPK_PRKDC_ST	P78527	PRKDC	P78527	PRKDC	S2677	S2675F	2675	Missense	proximal	-2	no	8.891	8.936	EPSD	COSMIC	8.283	Up-regulation
Atypical_PIKK_DNAPK_PRKDC_ST	P78527	PRKDC	P78527	PRKDC	S2677	H2682R	2682	Missense	distal	5	no	8.891	8.739	EPSD	COSMIC	8.283	Down-regulation
Atypical_PIKK_DNAPK_PRKDC_ST	P78527	PRKDC	P78527	PRKDC	S2677	A2681T	2681	Missense	distal	4	no	8.891	8.831	EPSD	COSMIC	8.283	Down-regulation
Atypical_PIKK_DNAPK_PRKDC_ST	P78527	PRKDC	P78527	PRKDC	S2677	A2681S	2681	Missense	distal	4	no	8.891	8.872	EPSD	COSMIC	8.283	Down-regulation
Atypical_PIKK_DNAPK_PRKDC_ST	P78527	PRKDC	P78527	PRKDC	S2677	P2673L	2673	Missense	distal	-4	no	8.891	8.848	EPSD	COSMIC	8.283	Down-regulation
Atypical_PIKK_DNAPK_PRKDC_ST	P78527	PRKDC	P78527	PRKDC	T2953	Q2954E	2954	Missense	proximal	1	no	10.523	2.788	EPSD	COSMIC	8.283	Loss
Atypical_PIKK_DNAPK_PRKDC_ST	P78527	PRKDC	P78527	PRKDC	T2953	E2960K	2960	Missense	distal	7	no	10.523	9.710	EPSD	COSMIC	8.283	Down-regulation
Atypical_PIKK_DNAPK_PRKDC_ST	P78527	PRKDC	P78527	PRKDC	S2998	L3005I	3005	Missense	distal	7	no	8.478	6.839	EPSD	COSMIC	8.283	Loss
Atypical_PIKK_DNAPK_PRKDC_ST	P78527	PRKDC	P78527	PRKDC	S2998	N3003K	3003	Missense	distal	5	no	8.478	8.428	EPSD	COSMIC	8.283	Down-regulation
Atypical_PIKK_DNAPK_PRKDC_ST	P78527	PRKDC	P78527	PRKDC	S3010	L3005I	3005	Missense	distal	-5	no	10.518	9.936	EPSD	COSMIC	8.283	Down-regulation
Atypical_PIKK_DNAPK_PRKDC_ST	P78527	PRKDC	P78527	PRKDC	S3010	N3003K	3003	Missense	distal	-7	no	10.518	10.625	EPSD	COSMIC	8.283	Up-regulation
Atypical_PIKK_DNAPK_PRKDC_ST	P78527	PRKDC	P78527	PRKDC	S3021	E3022D	3022	Missense	proximal	1	no	7.745	9.024	EPSD	COSMIC	8.283	Gain
Atypical_PIKK_DNAPK_PRKDC_ST	P78527	PRKDC	P78527	PRKDC	S3253	R3247L	3247	Missense	distal	-6	no	8.917	9.175	EPSD	COSMIC	8.283	Up-regulation
Atypical_PIKK_DNAPK_PRKDC_ST	P78527	PRKDC	P78527	PRKDC	S3253	N3250S	3250	Missense	distal	-3	no	8.917	8.738	EPSD	COSMIC	8.283	Down-regulation
Atypical_PIKK_DNAPK_PRKDC_ST	P78527	PRKDC	P78527	PRKDC	S3253	A3255D	3255	Missense	proximal	2	no	8.917	9.965	EPSD	COSMIC	8.283	Up-regulation
Atypical_PIKK_DNAPK_PRKDC_ST	P78527	PRKDC	P78527	PRKDC	S3253	K3248T	3248	Missense	distal	-5	no	8.917	8.709	EPSD	COSMIC	8.283	Down-regulation
Atypical_PIKK_DNAPK_PRKDC_ST	P78527	PRKDC	P78527	PRKDC	S3253	N3251K	3251	Missense	proximal	-2	no	8.917	8.985	EPSD	COSMIC	8.283	Up-regulation
Atypical_PIKK_DNAPK_PRKDC_ST	P78527	PRKDC	P78527	PRKDC	S3290	E3295Q	3295	Missense	distal	5	no	9.103	9.113	EPSD	COSMIC	8.283	Up-regulation
Atypical_PIKK_DNAPK_PRKDC_ST	P78527	PRKDC	P78527	PRKDC	S3290	R3287Q	3287	Missense	distal	-3	no	9.103	9.627	EPSD	COSMIC	8.283	Up-regulation
Atypical_PIKK_DNAPK_PRKDC_ST	P78527	PRKDC	P78527	PRKDC	S3290	Q3296H	3296	Missense	distal	6	no	9.103	9.093	EPSD	COSMIC	8.283	Down-regulation
Atypical_PIKK_DNAPK_PRKDC_ST	P78527	PRKDC	P78527	PRKDC	S3290	C3293Y	3293	Missense	distal	3	no	9.103	9.310	EPSD	COSMIC	8.283	Up-regulation
Atypical_PIKK_DNAPK_PRKDC_ST	P78527	PRKDC	P78527	PRKDC	S3290	R3289W	3289	Missense	proximal	-1	no	9.103	8.752	EPSD	COSMIC	8.283	Down-regulation
Atypical_PIKK_DNAPK_PRKDC_ST	P78527	PRKDC	P78527	PRKDC	S3290	H3285Y	3285	Missense	distal	-5	no	9.103	8.776	EPSD	COSMIC	8.283	Down-regulation
Atypical_PIKK_DNAPK_PRKDC_ST	P78527	PRKDC	P78527	PRKDC	S3290	S3294F	3294	Missense	distal	4	no	9.103	9.077	EPSD	COSMIC	8.283	Down-regulation
Atypical_PIKK_DNAPK_PRKDC_ST	P78527	PRKDC	P78527	PRKDC	S3294	E3295Q	3295	Missense	proximal	1	no	1.959	9.694	EPSD	COSMIC	8.283	Gain
Atypical_PIKK_DNAPK_PRKDC_ST	P78527	PRKDC	P78527	PRKDC	S3314	L3316S	3316	Missense	proximal	2	no	7.806	8.995	EPSD	COSMIC	8.283	Gain
Atypical_PIKK_DNAPK_PRKDC_ST	P78527	PRKDC	P78527	PRKDC	S3436	V3433G	3433	Missense	distal	-3	no	8.269	8.359	EPSD	COSMIC	8.283	Gain
Atypical_PIKK_DNAPK_PRKDC_ST	P78527	PRKDC	P78527	PRKDC	S3436	A3441E	3441	Missense	distal	5	no	8.269	8.354	EPSD	COSMIC	8.283	Gain
Atypical_PIKK_DNAPK_PRKDC_ST	P78527	PRKDC	P78527	PRKDC	S3821	A3826V	3826	Missense	distal	5	no	11.993	11.815	EPSD	COSMIC	8.283	Down-regulation
Atypical_PIKK_DNAPK_PRKDC_ST	P78527	PRKDC	P78527	PRKDC	S3821	L3815R	3815	Missense	distal	-6	no	11.993	11.735	EPSD	COSMIC	8.283	Down-regulation
Atypical_PIKK_DNAPK_PRKDC_ST	P78527	PRKDC	P78527	PRKDC	S3821	A3826T	3826	Missense	distal	5	no	11.993	11.828	EPSD	COSMIC	8.283	Down-regulation
Atypical_PIKK_DNAPK_PRKDC_ST	P78527	PRKDC	P78527	PRKDC	S3821	L3816P	3816	Missense	distal	-5	no	11.993	11.981	EPSD	COSMIC	8.283	Down-regulation
Atypical_PIKK_DNAPK_PRKDC_ST	P78527	PRKDC	P78527	PRKDC	S3821	S3821P	3821	Missense	central	0	yes	11.993	0.000	EPSD	COSMIC	8.283	Loss
Atypical_PIKK_DNAPK_PRKDC_ST	P78527	PRKDC	P78527	PRKDC	T3950	G3947D	3947	Missense	distal	-3	no	12.913	13.080	EPSD;PhosphoSitePlus	COSMIC	8.283	Up-regulation
Atypical_PIKK_DNAPK_PRKDC_ST	P78527	PRKDC	P78527	PRKDC	T3950	G3947V	3947	Missense	distal	-3	no	12.913	12.823	EPSD;PhosphoSitePlus	COSMIC	8.283	Down-regulation
Atypical_PIKK_DNAPK_PRKDC_ST	P78527	PRKDC	P78527	PRKDC	T3950	S3948F	3948	Missense	proximal	-2	no	12.913	12.958	EPSD;PhosphoSitePlus	COSMIC	8.283	Up-regulation
Atypical_PIKK_DNAPK_PRKDC_ST	P78527	PRKDC	P78527	PRKDC	T3950	H3944N	3944	Missense	distal	-6	no	12.913	13.002	EPSD;PhosphoSitePlus	COSMIC	8.283	Up-regulation
Atypical_PIKK_DNAPK_PRKDC_ST	P78527	PRKDC	P78527	PRKDC	T4102	V4104L	4104	Missense	proximal	2	no	12.846	13.315	EPSD	COSMIC	8.283	Up-regulation
Atypical_PIKK_DNAPK_PRKDC_ST	P14859	POU2F1	P78527	PRKDC	T21	G15R	15	Missense	distal	-6	no	12.609	12.401	EPSD	COSMIC	8.283	Down-regulation
Atypical_PIKK_DNAPK_PRKDC_ST	P14859	POU2F1	P78527	PRKDC	T21	N18S	18	Missense	distal	-3	no	12.609	12.430	EPSD	COSMIC	8.283	Down-regulation
Atypical_PIKK_DNAPK_PRKDC_ST	P14859	POU2F1	P78527	PRKDC	T21	D16Y	16	Missense	distal	-5	no	12.609	12.427	EPSD	COSMIC	8.283	Down-regulation
Atypical_PIKK_DNAPK_PRKDC_ST	P14859	POU2F1	P78527	PRKDC	T21	G20S	20	Missense	proximal	-1	no	12.609	12.872	EPSD	COSMIC	8.283	Up-regulation
Atypical_PIKK_DNAPK_PRKDC_ST	P14859	POU2F1	P78527	PRKDC	T21	T19A	19	Missense	proximal	-2	no	12.609	12.528	EPSD	COSMIC	8.283	Down-regulation
Atypical_PIKK_DNAPK_PRKDC_ST	P14859	POU2F1	P78527	PRKDC	T21	N24S	24	Missense	distal	3	no	12.609	12.567	EPSD	COSMIC	8.283	Down-regulation
Atypical_PIKK_DNAPK_PRKDC_ST	P14859	POU2F1	P78527	PRKDC	T21	G25D	25	Missense	distal	4	no	12.609	12.612	EPSD	COSMIC	8.283	Up-regulation
Atypical_PIKK_DNAPK_PRKDC_ST	P14859	POU2F1	P78527	PRKDC	S78	S72G	72	Missense	distal	-6	no	9.660	9.364	EPSD;PhosphoSitePlus	COSMIC	8.283	Down-regulation
Atypical_PIKK_DNAPK_PRKDC_ST	P14859	POU2F1	P78527	PRKDC	S78	Q83H	83	Missense	distal	5	no	9.660	9.490	EPSD;PhosphoSitePlus	COSMIC	8.283	Down-regulation
Atypical_PIKK_DNAPK_PRKDC_ST	P14859	POU2F1	P78527	PRKDC	S78	P84T	84	Missense	distal	6	no	9.660	9.646	EPSD;PhosphoSitePlus	COSMIC	8.283	Down-regulation
Atypical_PIKK_DNAPK_PRKDC_ST	P14859	POU2F1	P78527	PRKDC	S78	D80N	80	Missense	proximal	2	no	9.660	7.716	EPSD;PhosphoSitePlus	COSMIC	8.283	Loss
Atypical_PIKK_DNAPK_PRKDC_ST	P14859	POU2F1	P78527	PRKDC	S78	S72F	72	Missense	distal	-6	no	9.660	9.168	EPSD;PhosphoSitePlus	COSMIC;GDSC	8.283	Down-regulation
Atypical_PIKK_DNAPK_PRKDC_ST	P14859	POU2F1	P78527	PRKDC	S81	Q83H	83	Missense	proximal	2	no	15.888	15.431	EPSD;PhosphoSitePlus	COSMIC	8.283	Down-regulation
Atypical_PIKK_DNAPK_PRKDC_ST	P14859	POU2F1	P78527	PRKDC	S81	S88F	88	Missense	distal	7	no	15.888	15.185	EPSD;PhosphoSitePlus	COSMIC;GDSC;CCLE	8.283	Down-regulation
Atypical_PIKK_DNAPK_PRKDC_ST	P14859	POU2F1	P78527	PRKDC	S81	P84T	84	Missense	distal	3	no	15.888	15.615	EPSD;PhosphoSitePlus	COSMIC	8.283	Down-regulation
Atypical_PIKK_DNAPK_PRKDC_ST	P14859	POU2F1	P78527	PRKDC	S81	D80N	80	Missense	proximal	-1	no	15.888	15.146	EPSD;PhosphoSitePlus	COSMIC	8.283	Down-regulation
Atypical_PIKK_DNAPK_PRKDC_ST	P14859	POU2F1	P78527	PRKDC	S85	Q83H	83	Missense	proximal	-2	no	15.039	15.157	EPSD;PhosphoSitePlus	COSMIC	8.283	Up-regulation
Atypical_PIKK_DNAPK_PRKDC_ST	P14859	POU2F1	P78527	PRKDC	S85	S88F	88	Missense	distal	3	no	15.039	14.754	EPSD;PhosphoSitePlus	COSMIC;GDSC;CCLE	8.283	Down-regulation
Atypical_PIKK_DNAPK_PRKDC_ST	P14859	POU2F1	P78527	PRKDC	S85	P84T	84	Missense	proximal	-1	no	15.039	14.214	EPSD;PhosphoSitePlus	COSMIC	8.283	Down-regulation
Atypical_PIKK_DNAPK_PRKDC_ST	P14859	POU2F1	P78527	PRKDC	S85	D80N	80	Missense	distal	-5	no	15.039	15.049	EPSD;PhosphoSitePlus	COSMIC	8.283	Up-regulation
Atypical_PIKK_DNAPK_PRKDC_ST	P14859	POU2F1	P78527	PRKDC	S88	Q83H	83	Missense	distal	-5	no	14.542	14.561	EPSD;PhosphoSitePlus	COSMIC	8.283	Up-regulation
Atypical_PIKK_DNAPK_PRKDC_ST	P14859	POU2F1	P78527	PRKDC	S88	S88F	88	Missense	central	0	yes	14.542	0.000	EPSD;PhosphoSitePlus	COSMIC;GDSC;CCLE	8.283	Loss
Atypical_PIKK_DNAPK_PRKDC_ST	P14859	POU2F1	P78527	PRKDC	S88	P84T	84	Missense	distal	-4	no	14.542	14.297	EPSD;PhosphoSitePlus	COSMIC	8.283	Down-regulation
Atypical_PIKK_DNAPK_PRKDC_ST	P14859	POU2F1	P78527	PRKDC	S92	S88F	88	Missense	distal	-4	no	9.504	8.989	PhosphoSitePlus;EPSD	COSMIC;GDSC;CCLE	8.283	Down-regulation
Atypical_PIKK_DNAPK_PRKDC_ST	P14859	POU2F1	P78527	PRKDC	S92	A96T	96	Missense	distal	4	no	9.504	9.444	PhosphoSitePlus;EPSD	COSMIC	8.283	Down-regulation
Atypical_PIKK_DNAPK_PRKDC_ST	P14859	POU2F1	P78527	PRKDC	T100	A96T	96	Missense	distal	-4	no	12.846	12.274	EPSD;PhosphoSitePlus	COSMIC	8.283	Down-regulation
Atypical_PIKK_DNAPK_PRKDC_ST	P14859	POU2F1	P78527	PRKDC	S141	S143I	143	Missense	proximal	2	no	11.031	8.169	EPSD;PhosphoSitePlus	COSMIC	8.283	Loss
Atypical_PIKK_DNAPK_PRKDC_ST	P14859	POU2F1	P78527	PRKDC	S141	A142P	142	Missense	proximal	1	no	11.031	11.855	EPSD;PhosphoSitePlus	COSMIC	8.283	Up-regulation
Atypical_PIKK_DNAPK_PRKDC_ST	P14859	POU2F1	P78527	PRKDC	S143	S143I	143	Missense	central	0	yes	13.593	0.000	EPSD;PhosphoSitePlus	COSMIC	8.283	Loss
Atypical_PIKK_DNAPK_PRKDC_ST	P14859	POU2F1	P78527	PRKDC	S143	A142P	142	Missense	proximal	-1	no	13.593	13.523	EPSD;PhosphoSitePlus	COSMIC	8.283	Down-regulation
Atypical_PIKK_DNAPK_PRKDC_ST	P14859	POU2F1	P78527	PRKDC	S147	S143I	143	Missense	distal	-4	no	10.002	8.738	EPSD;PhosphoSitePlus	COSMIC	8.283	Down-regulation
Atypical_PIKK_DNAPK_PRKDC_ST	P14859	POU2F1	P78527	PRKDC	S147	A142P	142	Missense	distal	-5	no	10.002	9.767	EPSD;PhosphoSitePlus	COSMIC	8.283	Down-regulation
Atypical_PIKK_DNAPK_PRKDC_ST	P14859	POU2F1	P78527	PRKDC	T162	M161T	161	Missense	proximal	-1	no	10.276	10.646	EPSD;PhosphoSitePlus	COSMIC	8.283	Up-regulation
Atypical_PIKK_DNAPK_PRKDC_ST	P14859	POU2F1	P78527	PRKDC	T162	P165S	165	Missense	distal	3	no	10.276	10.322	EPSD;PhosphoSitePlus	COSMIC	8.283	Up-regulation
Atypical_PIKK_DNAPK_PRKDC_ST	P14859	POU2F1	P78527	PRKDC	T162	P160A	160	Missense	proximal	-2	no	10.276	10.240	EPSD;PhosphoSitePlus	COSMIC	8.283	Down-regulation
Atypical_PIKK_DNAPK_PRKDC_ST	P14859	POU2F1	P78527	PRKDC	S167	M161T	161	Missense	distal	-6	no	11.464	11.597	EPSD;PhosphoSitePlus	COSMIC	8.283	Up-regulation
Atypical_PIKK_DNAPK_PRKDC_ST	P14859	POU2F1	P78527	PRKDC	S167	P165S	165	Missense	proximal	-2	no	11.464	11.439	EPSD;PhosphoSitePlus	COSMIC	8.283	Down-regulation
Atypical_PIKK_DNAPK_PRKDC_ST	P14859	POU2F1	P78527	PRKDC	S167	P160A	160	Missense	distal	-7	no	11.464	12.061	EPSD;PhosphoSitePlus	COSMIC	8.283	Up-regulation
Atypical_PIKK_DNAPK_PRKDC_ST	P14859	POU2F1	P78527	PRKDC	T226	N223Y	223	Missense	distal	-3	no	12.076	12.136	EPSD;PhosphoSitePlus	COSMIC	8.283	Up-regulation
Atypical_PIKK_DNAPK_PRKDC_ST	P14859	POU2F1	P78527	PRKDC	T226	N223S	223	Missense	distal	-3	no	12.076	11.897	EPSD;PhosphoSitePlus	COSMIC	8.283	Down-regulation
Atypical_PIKK_DNAPK_PRKDC_ST	P14859	POU2F1	P78527	PRKDC	S358	E354D	354	Missense	distal	-4	no	9.180	9.163	EPSD	COSMIC	8.283	Down-regulation
Atypical_PIKK_DNAPK_PRKDC_ST	P14859	POU2F1	P78527	PRKDC	S358	P365S	365	Missense	distal	7	no	9.180	9.307	EPSD	COSMIC	8.283	Up-regulation
Atypical_PIKK_DNAPK_PRKDC_ST	P14859	POU2F1	P78527	PRKDC	S361	E354D	354	Missense	distal	-7	no	9.604	9.392	EPSD	COSMIC	8.283	Down-regulation
Atypical_PIKK_DNAPK_PRKDC_ST	P14859	POU2F1	P78527	PRKDC	S361	P365S	365	Missense	distal	4	no	9.604	9.630	EPSD	COSMIC	8.283	Up-regulation
Atypical_PIKK_DNAPK_PRKDC_ST	P14859	POU2F1	P78527	PRKDC	S364	P365S	365	Missense	proximal	1	no	9.327	4.972	EPSD	COSMIC	8.283	Loss
Atypical_PIKK_DNAPK_PRKDC_ST	P14859	POU2F1	P78527	PRKDC	S370	E374Q	374	Missense	distal	4	no	9.575	9.581	EPSD	COSMIC	8.283	Up-regulation
Atypical_PIKK_DNAPK_PRKDC_ST	P14859	POU2F1	P78527	PRKDC	S370	P365S	365	Missense	distal	-5	no	9.575	9.946	EPSD	COSMIC	8.283	Up-regulation
Atypical_PIKK_DNAPK_PRKDC_ST	P35637	FUS	P78527	PRKDC	T11	G15R	15	Missense	distal	4	no	13.935	13.903	EPSD;PhosphoSitePlus	COSMIC	8.283	Down-regulation
Atypical_PIKK_DNAPK_PRKDC_ST	P35637	FUS	P78527	PRKDC	T19	G15R	15	Missense	distal	-4	no	14.852	14.702	PhosphoSitePlus;EPSD	COSMIC	8.283	Down-regulation
Atypical_PIKK_DNAPK_PRKDC_ST	P35637	FUS	P78527	PRKDC	S61	G67E	67	Missense	distal	6	no	13.316	13.348	EPSD;PhosphoSitePlus	COSMIC	8.283	Up-regulation
Atypical_PIKK_DNAPK_PRKDC_ST	P35637	FUS	P78527	PRKDC	T68	G67E	67	Missense	proximal	-1	no	10.761	12.029	EPSD;PhosphoSitePlus	COSMIC	8.283	Up-regulation
Atypical_PIKK_DNAPK_PRKDC_ST	P35637	FUS	P78527	PRKDC	T68	Q69E	69	Missense	proximal	1	no	10.761	3.026	EPSD;PhosphoSitePlus	COSMIC	8.283	Loss
Atypical_PIKK_DNAPK_PRKDC_ST	P35637	FUS	P78527	PRKDC	S84	Q85H	85	Missense	proximal	1	no	14.024	3.689	EPSD;PhosphoSitePlus	COSMIC	8.283	Loss
Atypical_PIKK_DNAPK_PRKDC_ST	P35637	FUS	P78527	PRKDC	S84	S87T	87	Missense	distal	3	no	14.024	13.704	EPSD;PhosphoSitePlus	COSMIC	8.283	Down-regulation
Atypical_PIKK_DNAPK_PRKDC_ST	P35637	FUS	P78527	PRKDC	S87	G92R	92	Missense	distal	5	no	14.114	14.025	EPSD;PhosphoSitePlus	COSMIC	8.283	Down-regulation
Atypical_PIKK_DNAPK_PRKDC_ST	P35637	FUS	P78527	PRKDC	S87	Q85H	85	Missense	proximal	-2	no	14.114	14.232	EPSD;PhosphoSitePlus	COSMIC	8.283	Up-regulation
Atypical_PIKK_DNAPK_PRKDC_ST	P35637	FUS	P78527	PRKDC	S112	S119R	119	Missense	distal	7	no	9.169	8.012	EPSD;PhosphoSitePlus	COSMIC	8.283	Loss
Atypical_PIKK_DNAPK_PRKDC_ST	P35637	FUS	P78527	PRKDC	S112	P106L	106	Missense	distal	-6	no	9.169	9.288	EPSD;PhosphoSitePlus	COSMIC;GDSC;CCLE	8.283	Up-regulation
Atypical_PIKK_DNAPK_PRKDC_ST	P35637	FUS	P78527	PRKDC	S117	S119R	119	Missense	proximal	2	no	14.037	12.762	EPSD;PhosphoSitePlus	COSMIC	8.283	Down-regulation
Atypical_PIKK_DNAPK_PRKDC_ST	P35637	FUS	P78527	PRKDC	S131	G137A	137	Missense	distal	6	no	14.280	14.289	EPSD;PhosphoSitePlus	COSMIC	8.283	Up-regulation
Atypical_PIKK_DNAPK_PRKDC_ST	P35637	FUS	P78527	PRKDC	S131	G128E	128	Missense	distal	-3	no	14.280	14.560	EPSD;PhosphoSitePlus	COSMIC	8.283	Up-regulation
Atypical_PIKK_DNAPK_PRKDC_ST	P35637	FUS	P78527	PRKDC	S131	G138A	138	Missense	distal	7	no	14.280	14.757	EPSD;PhosphoSitePlus	COSMIC	8.283	Up-regulation
Atypical_PIKK_DNAPK_PRKDC_ST	P35637	FUS	P78527	PRKDC	S142	Q139P	139	Missense	distal	-3	no	10.787	10.653	EPSD;PhosphoSitePlus	COSMIC	8.283	Down-regulation
Atypical_PIKK_DNAPK_PRKDC_ST	P35637	FUS	P78527	PRKDC	S142	G137A	137	Missense	distal	-5	no	10.787	10.953	EPSD;PhosphoSitePlus	COSMIC	8.283	Up-regulation
Atypical_PIKK_DNAPK_PRKDC_ST	P35637	FUS	P78527	PRKDC	S142	G138A	138	Missense	distal	-4	no	10.787	11.158	EPSD;PhosphoSitePlus	COSMIC	8.283	Up-regulation
Atypical_PIKK_DNAPK_PRKDC_ST	P12956	XRCC6	P78527	PRKDC	S27	D29N	29	Missense	proximal	2	no	10.764	8.820	PhosphoSitePlus;EPSD	COSMIC	8.283	Down-regulation
Atypical_PIKK_DNAPK_PRKDC_ST	P12956	XRCC6	P78527	PRKDC	S27	G28E	28	Missense	proximal	1	no	10.764	9.778	PhosphoSitePlus;EPSD	COSMIC;GDSC	8.283	Down-regulation
Atypical_PIKK_DNAPK_PRKDC_ST	P12956	XRCC6	P78527	PRKDC	S33	D29N	29	Missense	distal	-4	no	10.289	10.325	EPSD;PhosphoSitePlus	COSMIC	8.283	Up-regulation
Atypical_PIKK_DNAPK_PRKDC_ST	P12956	XRCC6	P78527	PRKDC	S33	G28E	28	Missense	distal	-5	no	10.289	10.610	EPSD;PhosphoSitePlus	COSMIC;GDSC	8.283	Up-regulation
Atypical_PIKK_DNAPK_PRKDC_ST	P12956	XRCC6	P78527	PRKDC	S51	M48V	48	Missense	distal	-3	no	15.081	15.102	EPSD;PhosphoSitePlus	COSMIC	8.283	Up-regulation
Atypical_PIKK_DNAPK_PRKDC_ST	P12956	XRCC6	P78527	PRKDC	T58	Q65K	65	Missense	distal	7	no	10.382	9.473	EPSD	COSMIC	8.283	Down-regulation
Atypical_PIKK_DNAPK_PRKDC_ST	Q96SD1	DCLRE1C	P78527	PRKDC	T13	I14V	14	Missense	proximal	1	no	1.914	8.829	EPSD	COSMIC	8.283	Gain
Atypical_PIKK_DNAPK_PRKDC_ST	Q96SD1	DCLRE1C	P78527	PRKDC	T251	H254Y	254	Missense	distal	3	no	8.371	8.383	EPSD	COSMIC	8.283	Up-regulation
Atypical_PIKK_DNAPK_PRKDC_ST	Q96SD1	DCLRE1C	P78527	PRKDC	S503	S510R	510	Missense	distal	7	no	10.546	9.389	PhosphoSitePlus;EPSD	COSMIC	8.283	Down-regulation
Atypical_PIKK_DNAPK_PRKDC_ST	Q96SD1	DCLRE1C	P78527	PRKDC	S503	E498D	498	Missense	distal	-5	no	10.546	10.363	PhosphoSitePlus;EPSD	COSMIC;GDSC;CCLE	8.283	Down-regulation
Atypical_PIKK_DNAPK_PRKDC_ST	Q96SD1	DCLRE1C	P78527	PRKDC	S503	N506D	506	Missense	distal	3	no	10.546	10.540	PhosphoSitePlus;EPSD	COSMIC	8.283	Down-regulation
Atypical_PIKK_DNAPK_PRKDC_ST	Q96SD1	DCLRE1C	P78527	PRKDC	S503	F507V	507	Missense	distal	4	no	10.546	10.523	PhosphoSitePlus;EPSD	COSMIC;CCLE	8.283	Down-regulation
Atypical_PIKK_DNAPK_PRKDC_ST	Q96SD1	DCLRE1C	P78527	PRKDC	S516	S510R	510	Missense	distal	-6	no	12.866	12.362	EPSD;PhosphoSitePlus	COSMIC	8.283	Down-regulation
Atypical_PIKK_DNAPK_PRKDC_ST	Q96SD1	DCLRE1C	P78527	PRKDC	S516	S518L	518	Missense	proximal	2	no	12.866	11.677	EPSD;PhosphoSitePlus	COSMIC	8.283	Down-regulation
Atypical_PIKK_DNAPK_PRKDC_ST	Q96SD1	DCLRE1C	P78527	PRKDC	S518	S518L	518	Missense	central	0	yes	9.168	0.000	EPSD	COSMIC	8.283	Loss
Atypical_PIKK_DNAPK_PRKDC_ST	Q96SD1	DCLRE1C	P78527	PRKDC	S518	S525F	525	Missense	distal	7	no	9.168	8.465	EPSD	COSMIC	8.283	Down-regulation
Atypical_PIKK_DNAPK_PRKDC_ST	Q96SD1	DCLRE1C	P78527	PRKDC	S534	S534F	534	Missense	central	0	yes	11.868	0.000	EPSD;PhosphoSitePlus	COSMIC	8.283	Loss
Atypical_PIKK_DNAPK_PRKDC_ST	Q96SD1	DCLRE1C	P78527	PRKDC	S538	E545D	545	Missense	distal	7	no	13.949	14.039	EPSD;PhosphoSitePlus	COSMIC	8.283	Up-regulation
Atypical_PIKK_DNAPK_PRKDC_ST	Q96SD1	DCLRE1C	P78527	PRKDC	S538	S534F	534	Missense	distal	-4	no	13.949	13.433	EPSD;PhosphoSitePlus	COSMIC	8.283	Down-regulation
Atypical_PIKK_DNAPK_PRKDC_ST	Q96SD1	DCLRE1C	P78527	PRKDC	S548	E545D	545	Missense	distal	-3	no	10.820	10.707	EPSD;PhosphoSitePlus	COSMIC	8.283	Down-regulation
Atypical_PIKK_DNAPK_PRKDC_ST	Q96SD1	DCLRE1C	P78527	PRKDC	S553	D556H	556	Missense	distal	3	no	18.059	17.857	EPSD;PhosphoSitePlus	COSMIC	8.283	Down-regulation
Atypical_PIKK_DNAPK_PRKDC_ST	Q96SD1	DCLRE1C	P78527	PRKDC	S562	D569N	569	Missense	distal	7	no	13.528	12.862	EPSD	COSMIC	8.283	Down-regulation
Atypical_PIKK_DNAPK_PRKDC_ST	Q96SD1	DCLRE1C	P78527	PRKDC	S562	N566H	566	Missense	distal	4	no	13.528	13.491	EPSD	COSMIC	8.283	Down-regulation
Atypical_PIKK_DNAPK_PRKDC_ST	Q96SD1	DCLRE1C	P78527	PRKDC	S562	D556H	556	Missense	distal	-6	no	13.528	13.495	EPSD	COSMIC	8.283	Down-regulation
Atypical_PIKK_DNAPK_PRKDC_ST	Q96SD1	DCLRE1C	P78527	PRKDC	S562	Q563H	563	Missense	proximal	1	no	13.528	3.193	EPSD	COSMIC	8.283	Loss
Atypical_PIKK_DNAPK_PRKDC_ST	Q96SD1	DCLRE1C	P78527	PRKDC	S645	D650E	650	Missense	distal	5	no	12.975	13.007	EPSD;PhosphoSitePlus	COSMIC	8.283	Up-regulation
Atypical_PIKK_DNAPK_PRKDC_ST	Q96SD1	DCLRE1C	P78527	PRKDC	S645	S647N	647	Missense	proximal	2	no	12.975	12.052	EPSD;PhosphoSitePlus	COSMIC	8.283	Down-regulation
Atypical_PIKK_DNAPK_PRKDC_ST	Q96SD1	DCLRE1C	P78527	PRKDC	S645	L639F	639	Missense	distal	-6	no	12.975	12.729	EPSD;PhosphoSitePlus	COSMIC	8.283	Down-regulation
Atypical_PIKK_DNAPK_PRKDC_ST	Q96SD1	DCLRE1C	P78527	PRKDC	S645	S645F	645	Missense	central	0	yes	12.975	0.000	EPSD;PhosphoSitePlus	COSMIC	8.283	Loss
Atypical_PIKK_DNAPK_PRKDC_ST	P23508	MCC	P78527	PRKDC	S118	S118N	118	Missense	central	0	yes	14.462	0.000	EPSD;PhosphoSitePlus	COSMIC	8.283	Loss
Atypical_PIKK_DNAPK_PRKDC_ST	P23508	MCC	P78527	PRKDC	S120	S118N	118	Missense	proximal	-2	no	12.008	11.986	PhosphoSitePlus;EPSD	COSMIC	8.283	Down-regulation
Atypical_PIKK_DNAPK_PRKDC_ST	P23508	MCC	P78527	PRKDC	S182	G175S	175	Missense	distal	-7	no	9.659	10.202	EPSD	COSMIC	8.283	Up-regulation
Atypical_PIKK_DNAPK_PRKDC_ST	P23508	MCC	P78527	PRKDC	S184	S182T	182	Missense	proximal	-2	no	9.489	9.559	EPSD	COSMIC	8.283	Up-regulation
Atypical_PIKK_DNAPK_PRKDC_ST	P23508	MCC	P78527	PRKDC	S244	A247T	247	Missense	distal	3	no	9.678	9.423	EPSD	COSMIC	8.283	Down-regulation
Atypical_PIKK_DNAPK_PRKDC_ST	P23508	MCC	P78527	PRKDC	S244	S251N	251	Missense	distal	7	no	9.678	9.120	EPSD	COSMIC	8.283	Down-regulation
Atypical_PIKK_DNAPK_PRKDC_ST	P23508	MCC	P78527	PRKDC	S244	L249P	249	Missense	distal	5	no	9.678	9.722	EPSD	COSMIC	8.283	Up-regulation
Atypical_PIKK_DNAPK_PRKDC_ST	P23508	MCC	P78527	PRKDC	S412	R406W	406	Missense	distal	-6	no	10.789	10.302	EPSD	COSMIC	8.283	Down-regulation
Atypical_PIKK_DNAPK_PRKDC_ST	P23508	MCC	P78527	PRKDC	S485	S484A	484	Missense	proximal	-1	no	8.603	9.012	EPSD	COSMIC	8.283	Up-regulation
Atypical_PIKK_DNAPK_PRKDC_ST	P23508	MCC	P78527	PRKDC	S485	V482M	482	Missense	distal	-3	no	8.603	8.582	EPSD	COSMIC	8.283	Down-regulation
Atypical_PIKK_DNAPK_PRKDC_ST	P23508	MCC	P78527	PRKDC	S485	R478Q	478	Missense	distal	-7	no	8.603	9.417	EPSD	COSMIC	8.283	Up-regulation
Atypical_PIKK_DNAPK_PRKDC_ST	P23508	MCC	P78527	PRKDC	S485	A480S	480	Missense	distal	-5	no	8.603	8.739	EPSD	COSMIC	8.283	Up-regulation
Atypical_PIKK_DNAPK_PRKDC_ST	P23508	MCC	P78527	PRKDC	S485	S490F	490	Missense	distal	5	no	8.603	8.558	EPSD	COSMIC;CCLE	8.283	Down-regulation
Atypical_PIKK_DNAPK_PRKDC_ST	P23508	MCC	P78527	PRKDC	T496	K500N	500	Missense	distal	4	no	11.741	11.750	EPSD	COSMIC	8.283	Up-regulation
Atypical_PIKK_DNAPK_PRKDC_ST	P23508	MCC	P78527	PRKDC	T496	T496N	496	Missense	central	0	yes	11.741	0.000	EPSD	COSMIC	8.283	Loss
Atypical_PIKK_DNAPK_PRKDC_ST	P23508	MCC	P78527	PRKDC	T496	S490F	490	Missense	distal	-6	no	11.741	11.250	EPSD	COSMIC;CCLE	8.283	Down-regulation
Atypical_PIKK_DNAPK_PRKDC_ST	P23508	MCC	P78527	PRKDC	S681	G688D	688	Missense	distal	7	no	8.099	8.915	EPSD	COSMIC	8.283	Gain
Atypical_PIKK_DNAPK_PRKDC_ST	P23508	MCC	P78527	PRKDC	S706	S706C	706	Missense	central	0	yes	8.856	0.000	EPSD	COSMIC	8.283	Loss
Atypical_PIKK_DNAPK_PRKDC_ST	P23508	MCC	P78527	PRKDC	S706	D699H	699	Missense	distal	-7	no	8.856	9.174	EPSD	COSMIC	8.283	Up-regulation
Atypical_PIKK_DNAPK_PRKDC_ST	P23508	MCC	P78527	PRKDC	S792	S792L	792	Missense	central	0	yes	12.834	0.000	EPSD	COSMIC	8.283	Loss
Atypical_PIKK_DNAPK_PRKDC_ST	P23508	MCC	P78527	PRKDC	S792	A796V	796	Missense	distal	4	no	12.834	12.767	EPSD	COSMIC	8.283	Down-regulation
Atypical_PIKK_DNAPK_PRKDC_ST	P23508	MCC	P78527	PRKDC	S792	M795I	795	Missense	distal	3	no	12.834	12.424	EPSD	COSMIC	8.283	Down-regulation
Atypical_PIKK_DNAPK_PRKDC_ST	P23508	MCC	P78527	PRKDC	T803	L808P	808	Missense	distal	5	no	9.897	9.942	EPSD	COSMIC	8.283	Up-regulation
Atypical_PIKK_DNAPK_PRKDC_ST	P23508	MCC	P78527	PRKDC	T803	Q810K	810	Missense	distal	7	no	9.897	8.989	EPSD	COSMIC	8.283	Down-regulation
Atypical_PIKK_DNAPK_PRKDC_ST	P23508	MCC	P78527	PRKDC	T803	E802D	802	Missense	proximal	-1	no	9.897	9.643	EPSD	COSMIC	8.283	Down-regulation
Atypical_PIKK_DNAPK_PRKDC_ST	P23508	MCC	P78527	PRKDC	T803	A796V	796	Missense	distal	-7	no	9.897	8.975	EPSD	COSMIC	8.283	Down-regulation
Atypical_PIKK_DNAPK_PRKDC_ST	Q14653	IRF3	P78527	PRKDC	S123	P124L	124	Missense	proximal	1	no	8.768	8.707	EPSD	COSMIC	8.283	Down-regulation
Atypical_PIKK_DNAPK_PRKDC_ST	Q14653	IRF3	P78527	PRKDC	T135	D141N	141	Missense	distal	6	no	14.457	14.453	PhosphoSitePlus	COSMIC	8.283	Down-regulation
Atypical_PIKK_DNAPK_PRKDC_ST	Q14653	IRF3	P78527	PRKDC	T135	E137K	137	Missense	proximal	2	no	14.457	12.481	PhosphoSitePlus	COSMIC	8.283	Down-regulation
Atypical_PIKK_DNAPK_PRKDC_ST	Q14653	IRF3	P78527	PRKDC	T135	T132A	132	Missense	distal	-3	no	14.457	14.518	PhosphoSitePlus	COSMIC	8.283	Up-regulation
Atypical_PIKK_DNAPK_PRKDC_ST	Q14653	IRF3	P78527	PRKDC	S173	P166S	166	Missense	distal	-7	no	7.877	8.527	EPSD	COSMIC	8.283	Gain
Atypical_PIKK_DNAPK_PRKDC_ST	Q14653	IRF3	P78527	PRKDC	S175	Q169R	169	Missense	distal	-6	no	8.843	8.234	EPSD	COSMIC;CCLE	8.283	Loss
Atypical_PIKK_DNAPK_PRKDC_ST	Q14653	IRF3	P78527	PRKDC	S259	V261E	261	Missense	proximal	2	no	6.549	8.840	EPSD	COSMIC	8.283	Gain
Atypical_PIKK_DNAPK_PRKDC_ST	Q13426	XRCC4	P78527	PRKDC	S237	Q240E	240	Missense	distal	3	no	8.250	8.349	EPSD	COSMIC	8.283	Gain
Atypical_PIKK_DNAPK_PRKDC_ST	Q13426	XRCC4	P78527	PRKDC	S248	A250D	250	Missense	proximal	2	no	7.604	8.651	EPSD	COSMIC	8.283	Gain
Atypical_PIKK_DNAPK_PRKDC_ST	Q13426	XRCC4	P78527	PRKDC	S260	I258V	258	Missense	proximal	-2	no	10.057	9.912	EPSD;PhosphoSitePlus	COSMIC	8.283	Down-regulation
Atypical_PIKK_DNAPK_PRKDC_ST	Q13426	XRCC4	P78527	PRKDC	S304	K311R	311	Missense	distal	7	no	8.990	8.627	EPSD;PhosphoSitePlus	COSMIC	8.283	Down-regulation
Atypical_PIKK_DNAPK_PRKDC_ST	Q13426	XRCC4	P78527	PRKDC	S304	S303F	303	Missense	proximal	-1	no	8.990	9.253	EPSD;PhosphoSitePlus	COSMIC	8.283	Up-regulation
Atypical_PIKK_DNAPK_PRKDC_ST	Q13426	XRCC4	P78527	PRKDC	S304	K311M	311	Missense	distal	7	no	8.990	8.607	EPSD;PhosphoSitePlus	COSMIC	8.283	Down-regulation
Atypical_PIKK_DNAPK_PRKDC_ST	Q13426	XRCC4	P78527	PRKDC	S315	K311R	311	Missense	distal	-4	no	8.514	8.216	EPSD	COSMIC	8.283	Loss
Atypical_PIKK_DNAPK_PRKDC_ST	Q13426	XRCC4	P78527	PRKDC	S315	A316S	316	Missense	proximal	1	no	8.514	4.982	EPSD	COSMIC	8.283	Loss
Atypical_PIKK_DNAPK_PRKDC_ST	Q13426	XRCC4	P78527	PRKDC	S315	K311M	311	Missense	distal	-4	no	8.514	8.086	EPSD	COSMIC	8.283	Loss
Atypical_PIKK_DNAPK_PRKDC_ST	Q13426	XRCC4	P78527	PRKDC	S320	A316S	316	Missense	distal	-4	no	9.726	9.800	EPSD;PhosphoSitePlus	COSMIC	8.283	Up-regulation
Atypical_PIKK_DNAPK_PRKDC_ST	Q13426	XRCC4	P78527	PRKDC	T323	A316S	316	Missense	distal	-7	no	10.815	10.868	EPSD	COSMIC	8.283	Up-regulation
Atypical_PIKK_DNAPK_PRKDC_ST	Q13426	XRCC4	P78527	PRKDC	S328	D331H	331	Missense	distal	3	no	11.205	11.004	EPSD;PhosphoSitePlus	COSMIC	8.283	Down-regulation
Atypical_PIKK_DNAPK_PRKDC_ST	Q13426	XRCC4	P78527	PRKDC	S328	F333L	333	Missense	distal	5	no	11.205	11.174	EPSD;PhosphoSitePlus	COSMIC	8.283	Down-regulation
Atypical_PIKK_DNAPK_PRKDC_ST	Q13426	XRCC4	P78527	PRKDC	S328	D334Y	334	Missense	distal	6	no	11.205	11.208	EPSD;PhosphoSitePlus	COSMIC	8.283	Up-regulation
Atypical_PIKK_DNAPK_PRKDC_ST	Q14191	WRN	P78527	PRKDC	S319	D322V	322	Missense	distal	3	no	10.152	9.529	PhosphoSitePlus;EPSD	COSMIC	8.283	Down-regulation
Atypical_PIKK_DNAPK_PRKDC_ST	Q14191	WRN	P78527	PRKDC	S319	L317S	317	Missense	proximal	-2	no	10.152	10.129	PhosphoSitePlus;EPSD	COSMIC	8.283	Down-regulation
Atypical_PIKK_DNAPK_PRKDC_ST	Q14191	WRN	P78527	PRKDC	S319	N314I	314	Missense	distal	-5	no	10.152	9.367	PhosphoSitePlus;EPSD	COSMIC	8.283	Down-regulation
Atypical_PIKK_DNAPK_PRKDC_ST	Q14191	WRN	P78527	PRKDC	S409	I404N	404	Missense	distal	-5	no	14.826	15.612	EPSD	COSMIC	8.283	Up-regulation
Atypical_PIKK_DNAPK_PRKDC_ST	Q14191	WRN	P78527	PRKDC	S409	E406K	406	Missense	distal	-3	no	14.826	14.604	EPSD	COSMIC	8.283	Down-regulation
Atypical_PIKK_DNAPK_PRKDC_ST	Q14191	WRN	P78527	PRKDC	S426	D433N	433	Missense	distal	7	no	8.927	8.261	EPSD	COSMIC	8.283	Loss
Atypical_PIKK_DNAPK_PRKDC_ST	Q14191	WRN	P78527	PRKDC	S440	E447K	447	Missense	distal	7	no	10.299	9.487	EPSD;PhosphoSitePlus	COSMIC	8.283	Down-regulation
Atypical_PIKK_DNAPK_PRKDC_ST	Q14191	WRN	P78527	PRKDC	S440	S440N	440	Missense	central	0	yes	10.299	0.000	EPSD;PhosphoSitePlus	COSMIC	8.283	Loss
Atypical_PIKK_DNAPK_PRKDC_ST	Q14191	WRN	P78527	PRKDC	S440	M446I	446	Missense	distal	6	no	10.299	10.282	EPSD;PhosphoSitePlus	COSMIC;GDSC;CCLE	8.283	Down-regulation
Atypical_PIKK_DNAPK_PRKDC_ST	Q14191	WRN	P78527	PRKDC	S440	D433N	433	Missense	distal	-7	no	10.299	10.150	EPSD;PhosphoSitePlus	COSMIC	8.283	Down-regulation
Atypical_PIKK_DNAPK_PRKDC_ST	Q14191	WRN	P78527	PRKDC	S453	M448K	448	Missense	distal	-5	no	8.050	8.487	EPSD	COSMIC	8.283	Gain
Atypical_PIKK_DNAPK_PRKDC_ST	Q14191	WRN	P78527	PRKDC	S462	N459K	459	Missense	distal	-3	no	9.037	8.759	EPSD	COSMIC	8.283	Down-regulation
Atypical_PIKK_DNAPK_PRKDC_ST	Q14191	WRN	P78527	PRKDC	S467	M473I	473	Missense	distal	6	no	9.488	9.470	EPSD;PhosphoSitePlus	COSMIC;GDSC;CCLE	8.283	Down-regulation
Atypical_PIKK_DNAPK_PRKDC_ST	Q14191	WRN	P78527	PRKDC	S1002	R999C	999	Missense	distal	-3	no	9.018	9.034	EPSD	COSMIC	8.283	Up-regulation
Atypical_PIKK_DNAPK_PRKDC_ST	Q14191	WRN	P78527	PRKDC	S1058	Q1059E	1059	Missense	proximal	1	no	12.557	4.822	EPSD	COSMIC;GDSC;CCLE	8.283	Loss
Atypical_PIKK_DNAPK_PRKDC_ST	Q14191	WRN	P78527	PRKDC	S1133	K1126R	1126	Missense	distal	-7	no	11.445	10.988	EPSD	COSMIC	8.283	Down-regulation
Atypical_PIKK_DNAPK_PRKDC_ST	Q14191	WRN	P78527	PRKDC	S1133	A1137G	1137	Missense	distal	4	no	11.445	11.420	EPSD	COSMIC	8.283	Down-regulation
Atypical_PIKK_DNAPK_PRKDC_ST	Q14191	WRN	P78527	PRKDC	S1133	S1128G	1128	Missense	distal	-5	no	11.445	11.143	EPSD	COSMIC	8.283	Down-regulation
Atypical_PIKK_DNAPK_PRKDC_ST	Q14191	WRN	P78527	PRKDC	S1141	S1146L	1146	Missense	distal	5	no	15.405	15.328	EPSD	COSMIC	8.283	Down-regulation
Atypical_PIKK_DNAPK_PRKDC_ST	Q14191	WRN	P78527	PRKDC	S1141	A1137G	1137	Missense	distal	-4	no	15.405	15.034	EPSD	COSMIC	8.283	Down-regulation
Atypical_PIKK_DNAPK_PRKDC_ST	Q14191	WRN	P78527	PRKDC	S1141	A1147T	1147	Missense	distal	6	no	15.405	15.400	EPSD	COSMIC	8.283	Down-regulation
Atypical_PIKK_DNAPK_PRKDC_ST	P04637	TP53	P78527	PRKDC	S6	P8S	8	Missense	proximal	2	no	8.064	8.294	EPSD	COSMIC	8.283	Gain
Atypical_PIKK_DNAPK_PRKDC_ST	P04637	TP53	P78527	PRKDC	S6	D7Y	7	Missense	proximal	1	no	8.064	10.525	EPSD	COSMIC	8.283	Gain
Atypical_PIKK_DNAPK_PRKDC_ST	P04637	TP53	P78527	PRKDC	S9	E11Q	11	Missense	proximal	2	no	12.301	11.745	EPSD;PhosphoSitePlus	COSMIC;GDSC;CCLE	8.283	Down-regulation
Atypical_PIKK_DNAPK_PRKDC_ST	P04637	TP53	P78527	PRKDC	S9	Q16L	16	Missense	distal	7	no	12.301	11.432	EPSD;PhosphoSitePlus	COSMIC;GDSC;CCLE	8.283	Down-regulation
Atypical_PIKK_DNAPK_PRKDC_ST	P04637	TP53	P78527	PRKDC	S9	P13S	13	Missense	distal	4	no	12.301	12.327	EPSD;PhosphoSitePlus	COSMIC	8.283	Up-regulation
Atypical_PIKK_DNAPK_PRKDC_ST	P04637	TP53	P78527	PRKDC	S9	V10I	10	Missense	proximal	1	no	12.301	5.386	EPSD;PhosphoSitePlus	COSMIC	8.283	Loss
Atypical_PIKK_DNAPK_PRKDC_ST	P04637	TP53	P78527	PRKDC	S9	P8L	8	Missense	proximal	-1	no	12.301	12.000	EPSD;PhosphoSitePlus	COSMIC	8.283	Down-regulation
Atypical_PIKK_DNAPK_PRKDC_ST	P04637	TP53	P78527	PRKDC	S9	P8S	8	Missense	proximal	-1	no	12.301	11.961	EPSD;PhosphoSitePlus	COSMIC	8.283	Down-regulation
Atypical_PIKK_DNAPK_PRKDC_ST	P04637	TP53	P78527	PRKDC	S9	P13L	13	Missense	distal	4	no	12.301	12.307	EPSD;PhosphoSitePlus	COSMIC	8.283	Up-regulation
Atypical_PIKK_DNAPK_PRKDC_ST	P04637	TP53	P78527	PRKDC	S9	Q5H	5	Missense	distal	-4	no	12.301	12.055	EPSD;PhosphoSitePlus	COSMIC	8.283	Down-regulation
Atypical_PIKK_DNAPK_PRKDC_ST	P04637	TP53	P78527	PRKDC	S9	V10G	10	Missense	proximal	1	no	12.301	11.592	EPSD;PhosphoSitePlus	COSMIC	8.283	Down-regulation
Atypical_PIKK_DNAPK_PRKDC_ST	P04637	TP53	P78527	PRKDC	S9	E3G	3	Missense	distal	-6	no	12.301	11.966	EPSD;PhosphoSitePlus	COSMIC	8.283	Down-regulation
Atypical_PIKK_DNAPK_PRKDC_ST	P04637	TP53	P78527	PRKDC	S9	D7H	7	Missense	proximal	-2	no	12.301	12.342	EPSD;PhosphoSitePlus	COSMIC	8.283	Up-regulation
Atypical_PIKK_DNAPK_PRKDC_ST	P04637	TP53	P78527	PRKDC	S9	S9G	9	Missense	central	0	yes	12.301	0.000	EPSD;PhosphoSitePlus	COSMIC	8.283	Loss
Atypical_PIKK_DNAPK_PRKDC_ST	P04637	TP53	P78527	PRKDC	S9	S15I	15	Missense	distal	6	no	12.301	12.265	EPSD;PhosphoSitePlus	COSMIC	8.283	Down-regulation
Atypical_PIKK_DNAPK_PRKDC_ST	P04637	TP53	P78527	PRKDC	S9	D7Y	7	Missense	proximal	-2	no	12.301	12.298	EPSD;PhosphoSitePlus	COSMIC	8.283	Down-regulation
Atypical_PIKK_DNAPK_PRKDC_ST	P04637	TP53	P78527	PRKDC	S15	E11Q	11	Missense	distal	-4	no	14.028	14.173	EPSD;PhosphoSitePlus	COSMIC;GDSC;CCLE	8.283	Up-regulation
Atypical_PIKK_DNAPK_PRKDC_ST	P04637	TP53	P78527	PRKDC	S15	S20L	20	Missense	distal	5	no	14.028	13.952	EPSD;PhosphoSitePlus	COSMIC	8.283	Down-regulation
Atypical_PIKK_DNAPK_PRKDC_ST	P04637	TP53	P78527	PRKDC	S15	Q16L	16	Missense	proximal	1	no	14.028	9.486	EPSD;PhosphoSitePlus	COSMIC;GDSC;CCLE	8.283	Down-regulation
Atypical_PIKK_DNAPK_PRKDC_ST	P04637	TP53	P78527	PRKDC	S15	P13S	13	Missense	proximal	-2	no	14.028	14.004	EPSD;PhosphoSitePlus	COSMIC	8.283	Down-regulation
Atypical_PIKK_DNAPK_PRKDC_ST	P04637	TP53	P78527	PRKDC	S15	E17K	17	Missense	proximal	2	no	14.028	12.052	EPSD;PhosphoSitePlus	COSMIC	8.283	Down-regulation
Atypical_PIKK_DNAPK_PRKDC_ST	P04637	TP53	P78527	PRKDC	S15	V10I	10	Missense	distal	-5	no	14.028	13.716	EPSD;PhosphoSitePlus	COSMIC	8.283	Down-regulation
Atypical_PIKK_DNAPK_PRKDC_ST	P04637	TP53	P78527	PRKDC	S15	P8L	8	Missense	distal	-7	no	14.028	14.211	EPSD;PhosphoSitePlus	COSMIC	8.283	Up-regulation
Atypical_PIKK_DNAPK_PRKDC_ST	P04637	TP53	P78527	PRKDC	S15	P8S	8	Missense	distal	-7	no	14.028	14.678	EPSD;PhosphoSitePlus	COSMIC	8.283	Up-regulation
Atypical_PIKK_DNAPK_PRKDC_ST	P04637	TP53	P78527	PRKDC	S15	P13L	13	Missense	proximal	-2	no	14.028	14.027	EPSD;PhosphoSitePlus	COSMIC	8.283	Down-regulation
Atypical_PIKK_DNAPK_PRKDC_ST	P04637	TP53	P78527	PRKDC	S15	V10G	10	Missense	distal	-5	no	14.028	14.354	EPSD;PhosphoSitePlus	COSMIC	8.283	Up-regulation
Atypical_PIKK_DNAPK_PRKDC_ST	P04637	TP53	P78527	PRKDC	S15	T18A	18	Missense	distal	3	no	14.028	14.283	EPSD;PhosphoSitePlus	COSMIC	8.283	Up-regulation
Atypical_PIKK_DNAPK_PRKDC_ST	P04637	TP53	P78527	PRKDC	S15	F19S	19	Missense	distal	4	no	14.028	14.054	EPSD;PhosphoSitePlus	COSMIC	8.283	Up-regulation
Atypical_PIKK_DNAPK_PRKDC_ST	P04637	TP53	P78527	PRKDC	S15	E17V	17	Missense	proximal	2	no	14.028	11.737	EPSD;PhosphoSitePlus	COSMIC	8.283	Down-regulation
Atypical_PIKK_DNAPK_PRKDC_ST	P04637	TP53	P78527	PRKDC	S15	S9G	9	Missense	distal	-6	no	14.028	13.733	EPSD;PhosphoSitePlus	COSMIC	8.283	Down-regulation
Atypical_PIKK_DNAPK_PRKDC_ST	P04637	TP53	P78527	PRKDC	S15	T18I	18	Missense	distal	3	no	14.028	13.407	EPSD;PhosphoSitePlus	COSMIC	8.283	Down-regulation
Atypical_PIKK_DNAPK_PRKDC_ST	P04637	TP53	P78527	PRKDC	S15	T18K	18	Missense	distal	3	no	14.028	14.032	EPSD;PhosphoSitePlus	COSMIC	8.283	Up-regulation
Atypical_PIKK_DNAPK_PRKDC_ST	P04637	TP53	P78527	PRKDC	S15	T18R	18	Missense	distal	3	no	14.028	13.875	EPSD;PhosphoSitePlus	COSMIC	8.283	Down-regulation
Atypical_PIKK_DNAPK_PRKDC_ST	P04637	TP53	P78527	PRKDC	S15	S15I	15	Missense	central	0	yes	14.028	0.000	EPSD;PhosphoSitePlus	COSMIC	8.283	Loss
Atypical_PIKK_DNAPK_PRKDC_ST	P04637	TP53	P78527	PRKDC	T18	P13S	13	Missense	distal	-5	no	7.988	8.359	EPSD;PhosphoSitePlus	COSMIC	8.283	Gain
Atypical_PIKK_DNAPK_PRKDC_ST	P04637	TP53	P78527	PRKDC	S20	S20L	20	Missense	central	0	yes	8.830	0.000	EPSD;PhosphoSitePlus	COSMIC	8.283	Loss
Atypical_PIKK_DNAPK_PRKDC_ST	P04637	TP53	P78527	PRKDC	S20	Q16L	16	Missense	distal	-4	no	8.830	8.282	EPSD;PhosphoSitePlus	COSMIC;GDSC;CCLE	8.283	Loss
Atypical_PIKK_DNAPK_PRKDC_ST	P04637	TP53	P78527	PRKDC	S20	P13S	13	Missense	distal	-7	no	8.830	9.480	EPSD;PhosphoSitePlus	COSMIC	8.283	Up-regulation
Atypical_PIKK_DNAPK_PRKDC_ST	P04637	TP53	P78527	PRKDC	S20	E17K	17	Missense	distal	-3	no	8.830	8.607	EPSD;PhosphoSitePlus	COSMIC	8.283	Down-regulation
Atypical_PIKK_DNAPK_PRKDC_ST	P04637	TP53	P78527	PRKDC	S20	P13L	13	Missense	distal	-7	no	8.830	9.013	EPSD;PhosphoSitePlus	COSMIC	8.283	Up-regulation
Atypical_PIKK_DNAPK_PRKDC_ST	P04637	TP53	P78527	PRKDC	S20	L26P	26	Missense	distal	6	no	8.830	8.841	EPSD;PhosphoSitePlus	COSMIC	8.283	Up-regulation
Atypical_PIKK_DNAPK_PRKDC_ST	P04637	TP53	P78527	PRKDC	S20	T18A	18	Missense	proximal	-2	no	8.830	8.749	EPSD;PhosphoSitePlus	COSMIC	8.283	Down-regulation
Atypical_PIKK_DNAPK_PRKDC_ST	P04637	TP53	P78527	PRKDC	S20	F19S	19	Missense	proximal	-1	no	8.830	8.566	EPSD;PhosphoSitePlus	COSMIC	8.283	Down-regulation
Atypical_PIKK_DNAPK_PRKDC_ST	P04637	TP53	P78527	PRKDC	S20	E17V	17	Missense	distal	-3	no	8.830	8.460	EPSD;PhosphoSitePlus	COSMIC	8.283	Down-regulation
Atypical_PIKK_DNAPK_PRKDC_ST	P04637	TP53	P78527	PRKDC	S20	P27T	27	Missense	distal	7	no	8.830	8.109	EPSD;PhosphoSitePlus	COSMIC	8.283	Loss
Atypical_PIKK_DNAPK_PRKDC_ST	P04637	TP53	P78527	PRKDC	S20	T18I	18	Missense	proximal	-2	no	8.830	9.016	EPSD;PhosphoSitePlus	COSMIC	8.283	Up-regulation
Atypical_PIKK_DNAPK_PRKDC_ST	P04637	TP53	P78527	PRKDC	S20	T18K	18	Missense	proximal	-2	no	8.830	8.805	EPSD;PhosphoSitePlus	COSMIC	8.283	Down-regulation
Atypical_PIKK_DNAPK_PRKDC_ST	P04637	TP53	P78527	PRKDC	S20	T18R	18	Missense	proximal	-2	no	8.830	8.887	EPSD;PhosphoSitePlus	COSMIC	8.283	Up-regulation
Atypical_PIKK_DNAPK_PRKDC_ST	P04637	TP53	P78527	PRKDC	S20	S15I	15	Missense	distal	-5	no	8.830	7.890	EPSD;PhosphoSitePlus	COSMIC	8.283	Loss
Atypical_PIKK_DNAPK_PRKDC_ST	P04637	TP53	P78527	PRKDC	S33	M40I	40	Missense	distal	7	no	9.126	7.910	EPSD	COSMIC	8.283	Loss
Atypical_PIKK_DNAPK_PRKDC_ST	P04637	TP53	P78527	PRKDC	S33	V31I	31	Missense	proximal	-2	no	9.126	9.271	EPSD	COSMIC;GDSC;CCLE	8.283	Up-regulation
Atypical_PIKK_DNAPK_PRKDC_ST	P04637	TP53	P78527	PRKDC	S33	P36L	36	Missense	distal	3	no	9.126	8.791	EPSD	COSMIC;GDSC;CCLE	8.283	Down-regulation
Atypical_PIKK_DNAPK_PRKDC_ST	P04637	TP53	P78527	PRKDC	S33	L35F	35	Missense	proximal	2	no	9.126	9.213	EPSD	COSMIC	8.283	Up-regulation
Atypical_PIKK_DNAPK_PRKDC_ST	P04637	TP53	P78527	PRKDC	S33	Q38L	38	Missense	distal	5	no	9.126	8.933	EPSD	COSMIC	8.283	Down-regulation
Atypical_PIKK_DNAPK_PRKDC_ST	P04637	TP53	P78527	PRKDC	S33	S37T	37	Missense	distal	4	no	9.126	9.085	EPSD	COSMIC	8.283	Down-regulation
Atypical_PIKK_DNAPK_PRKDC_ST	P04637	TP53	P78527	PRKDC	S33	L26P	26	Missense	distal	-7	no	9.126	8.943	EPSD	COSMIC	8.283	Down-regulation
Atypical_PIKK_DNAPK_PRKDC_ST	P04637	TP53	P78527	PRKDC	S33	P36S	36	Missense	distal	3	no	9.126	9.173	EPSD	COSMIC;GDSC;CCLE	8.283	Up-regulation
Atypical_PIKK_DNAPK_PRKDC_ST	P04637	TP53	P78527	PRKDC	S33	A39V	39	Missense	distal	6	no	9.126	9.113	EPSD	COSMIC	8.283	Down-regulation
Atypical_PIKK_DNAPK_PRKDC_ST	P04637	TP53	P78527	PRKDC	S33	N30K	30	Missense	distal	-3	no	9.126	8.848	EPSD	COSMIC	8.283	Down-regulation
Atypical_PIKK_DNAPK_PRKDC_ST	P04637	TP53	P78527	PRKDC	S33	A39T	39	Missense	distal	6	no	9.126	9.122	EPSD	COSMIC	8.283	Down-regulation
Atypical_PIKK_DNAPK_PRKDC_ST	P04637	TP53	P78527	PRKDC	S33	P27T	27	Missense	distal	-6	no	9.126	9.143	EPSD	COSMIC	8.283	Up-regulation
Atypical_PIKK_DNAPK_PRKDC_ST	P04637	TP53	P78527	PRKDC	S33	P36R	36	Missense	distal	3	no	9.126	8.700	EPSD	COSMIC	8.283	Down-regulation
Atypical_PIKK_DNAPK_PRKDC_ST	P04637	TP53	P78527	PRKDC	S33	L35R	35	Missense	proximal	2	no	9.126	9.039	EPSD	COSMIC	8.283	Down-regulation
Atypical_PIKK_DNAPK_PRKDC_ST	P04637	TP53	P78527	PRKDC	S33	L35H	35	Missense	proximal	2	no	9.126	9.935	EPSD	COSMIC	8.283	Up-regulation
Atypical_PIKK_DNAPK_PRKDC_ST	P04637	TP53	P78527	PRKDC	S33	L35P	35	Missense	proximal	2	no	9.126	10.085	EPSD	COSMIC	8.283	Up-regulation
Atypical_PIKK_DNAPK_PRKDC_ST	P04637	TP53	P78527	PRKDC	S33	L35I	35	Missense	proximal	2	no	9.126	7.452	EPSD	COSMIC	8.283	Loss
Atypical_PIKK_DNAPK_PRKDC_ST	P04637	TP53	P78527	PRKDC	S33	L35V	35	Missense	proximal	2	no	9.126	8.657	EPSD	COSMIC	8.283	Down-regulation
Atypical_PIKK_DNAPK_PRKDC_ST	P04637	TP53	P78527	PRKDC	S37	M40I	40	Missense	distal	3	no	12.605	12.195	PhosphoSitePlus;EPSD	COSMIC	8.283	Down-regulation
Atypical_PIKK_DNAPK_PRKDC_ST	P04637	TP53	P78527	PRKDC	S37	V31I	31	Missense	distal	-6	no	12.605	12.091	PhosphoSitePlus;EPSD	COSMIC;GDSC;CCLE	8.283	Down-regulation
Atypical_PIKK_DNAPK_PRKDC_ST	P04637	TP53	P78527	PRKDC	S37	P36L	36	Missense	proximal	-1	no	12.605	12.304	PhosphoSitePlus;EPSD	COSMIC;GDSC;CCLE	8.283	Down-regulation
Atypical_PIKK_DNAPK_PRKDC_ST	P04637	TP53	P78527	PRKDC	S37	S33T	33	Missense	distal	-4	no	12.605	11.959	PhosphoSitePlus;EPSD	COSMIC	8.283	Down-regulation
Atypical_PIKK_DNAPK_PRKDC_ST	P04637	TP53	P78527	PRKDC	S37	D41N	41	Missense	distal	4	no	12.605	12.628	PhosphoSitePlus;EPSD	COSMIC	8.283	Up-regulation
Atypical_PIKK_DNAPK_PRKDC_ST	P04637	TP53	P78527	PRKDC	S37	L35F	35	Missense	proximal	-2	no	12.605	12.627	PhosphoSitePlus;EPSD	COSMIC	8.283	Up-regulation
Atypical_PIKK_DNAPK_PRKDC_ST	P04637	TP53	P78527	PRKDC	S37	Q38L	38	Missense	proximal	1	no	12.605	8.063	PhosphoSitePlus;EPSD	COSMIC	8.283	Loss
Atypical_PIKK_DNAPK_PRKDC_ST	P04637	TP53	P78527	PRKDC	S37	M44I	44	Missense	distal	7	no	12.605	11.388	PhosphoSitePlus;EPSD	COSMIC	8.283	Down-regulation
Atypical_PIKK_DNAPK_PRKDC_ST	P04637	TP53	P78527	PRKDC	S37	P36S	36	Missense	proximal	-1	no	12.605	12.265	PhosphoSitePlus;EPSD	COSMIC;GDSC;CCLE	8.283	Down-regulation
Atypical_PIKK_DNAPK_PRKDC_ST	P04637	TP53	P78527	PRKDC	S37	A39V	39	Missense	proximal	2	no	12.605	10.974	PhosphoSitePlus;EPSD	COSMIC	8.283	Down-regulation
Atypical_PIKK_DNAPK_PRKDC_ST	P04637	TP53	P78527	PRKDC	S37	A39S	39	Missense	proximal	2	no	12.605	12.632	PhosphoSitePlus;EPSD	COSMIC	8.283	Up-regulation
Atypical_PIKK_DNAPK_PRKDC_ST	P04637	TP53	P78527	PRKDC	S37	D42Y	42	Missense	distal	5	no	12.605	12.490	PhosphoSitePlus;EPSD	COSMIC	8.283	Down-regulation
Atypical_PIKK_DNAPK_PRKDC_ST	P04637	TP53	P78527	PRKDC	S37	M44R	44	Missense	distal	7	no	12.605	12.625	PhosphoSitePlus;EPSD	COSMIC	8.283	Up-regulation
Atypical_PIKK_DNAPK_PRKDC_ST	P04637	TP53	P78527	PRKDC	S37	M44V	44	Missense	distal	7	no	12.605	12.461	PhosphoSitePlus;EPSD	COSMIC	8.283	Down-regulation
Atypical_PIKK_DNAPK_PRKDC_ST	P04637	TP53	P78527	PRKDC	S37	N30K	30	Missense	distal	-7	no	12.605	12.712	PhosphoSitePlus;EPSD	COSMIC	8.283	Up-regulation
Atypical_PIKK_DNAPK_PRKDC_ST	P04637	TP53	P78527	PRKDC	S37	M44T	44	Missense	distal	7	no	12.605	12.934	PhosphoSitePlus;EPSD	COSMIC	8.283	Up-regulation
Atypical_PIKK_DNAPK_PRKDC_ST	P04637	TP53	P78527	PRKDC	S37	A39T	39	Missense	proximal	2	no	12.605	11.648	PhosphoSitePlus;EPSD	COSMIC	8.283	Down-regulation
Atypical_PIKK_DNAPK_PRKDC_ST	P04637	TP53	P78527	PRKDC	S37	L43F	43	Missense	distal	6	no	12.605	12.609	PhosphoSitePlus;EPSD	COSMIC	8.283	Up-regulation
Atypical_PIKK_DNAPK_PRKDC_ST	P04637	TP53	P78527	PRKDC	S37	D41H	41	Missense	distal	4	no	12.605	12.592	PhosphoSitePlus;EPSD	COSMIC	8.283	Down-regulation
Atypical_PIKK_DNAPK_PRKDC_ST	P04637	TP53	P78527	PRKDC	S37	P36R	36	Missense	proximal	-1	no	12.605	11.523	PhosphoSitePlus;EPSD	COSMIC	8.283	Down-regulation
Atypical_PIKK_DNAPK_PRKDC_ST	P04637	TP53	P78527	PRKDC	S37	L35R	35	Missense	proximal	-2	no	12.605	12.709	PhosphoSitePlus;EPSD	COSMIC	8.283	Up-regulation
Atypical_PIKK_DNAPK_PRKDC_ST	P04637	TP53	P78527	PRKDC	S37	L35H	35	Missense	proximal	-2	no	12.605	12.577	PhosphoSitePlus;EPSD	COSMIC	8.283	Down-regulation
Atypical_PIKK_DNAPK_PRKDC_ST	P04637	TP53	P78527	PRKDC	S37	L35P	35	Missense	proximal	-2	no	12.605	12.606	PhosphoSitePlus;EPSD	COSMIC	8.283	Up-regulation
Atypical_PIKK_DNAPK_PRKDC_ST	P04637	TP53	P78527	PRKDC	S37	L35I	35	Missense	proximal	-2	no	12.605	12.838	PhosphoSitePlus;EPSD	COSMIC	8.283	Up-regulation
Atypical_PIKK_DNAPK_PRKDC_ST	P04637	TP53	P78527	PRKDC	S37	L35V	35	Missense	proximal	-2	no	12.605	12.693	PhosphoSitePlus;EPSD	COSMIC	8.283	Up-regulation
Atypical_PIKK_DNAPK_PRKDC_ST	P04637	TP53	P78527	PRKDC	S37	D41E	41	Missense	distal	4	no	12.605	12.631	PhosphoSitePlus;EPSD	COSMIC	8.283	Up-regulation
Atypical_PIKK_DNAPK_PRKDC_ST	P04637	TP53	P78527	PRKDC	S46	M40I	40	Missense	distal	-6	no	8.858	8.112	EPSD;PhosphoSitePlus	COSMIC	8.283	Loss
Atypical_PIKK_DNAPK_PRKDC_ST	P04637	TP53	P78527	PRKDC	S46	W53C	53	Missense	distal	7	no	8.858	9.218	EPSD;PhosphoSitePlus	COSMIC	8.283	Up-regulation
Atypical_PIKK_DNAPK_PRKDC_ST	P04637	TP53	P78527	PRKDC	S46	W53G	53	Missense	distal	7	no	8.858	9.970	EPSD;PhosphoSitePlus	COSMIC	8.283	Up-regulation
Atypical_PIKK_DNAPK_PRKDC_ST	P04637	TP53	P78527	PRKDC	S46	S46F	46	Missense	central	0	yes	8.858	0.000	EPSD;PhosphoSitePlus	COSMIC	8.283	Loss
Atypical_PIKK_DNAPK_PRKDC_ST	P04637	TP53	P78527	PRKDC	S46	D49Y	49	Missense	distal	3	no	8.858	8.668	EPSD;PhosphoSitePlus	COSMIC	8.283	Down-regulation
Atypical_PIKK_DNAPK_PRKDC_ST	P04637	TP53	P78527	PRKDC	S46	P47L	47	Missense	proximal	1	no	8.858	8.797	EPSD;PhosphoSitePlus	COSMIC	8.283	Down-regulation
Atypical_PIKK_DNAPK_PRKDC_ST	P04637	TP53	P78527	PRKDC	S46	D49H	49	Missense	distal	3	no	8.858	8.656	EPSD;PhosphoSitePlus	COSMIC;GDSC;CCLE	8.283	Down-regulation
Atypical_PIKK_DNAPK_PRKDC_ST	P04637	TP53	P78527	PRKDC	S46	P47S	47	Missense	proximal	1	no	8.858	4.503	EPSD;PhosphoSitePlus	COSMIC	8.283	Loss
Atypical_PIKK_DNAPK_PRKDC_ST	P04637	TP53	P78527	PRKDC	S46	D41N	41	Missense	distal	-5	no	8.858	8.868	EPSD;PhosphoSitePlus	COSMIC	8.283	Up-regulation
Atypical_PIKK_DNAPK_PRKDC_ST	P04637	TP53	P78527	PRKDC	S46	D48H	48	Missense	proximal	2	no	8.858	7.458	EPSD;PhosphoSitePlus	COSMIC	8.283	Loss
Atypical_PIKK_DNAPK_PRKDC_ST	P04637	TP53	P78527	PRKDC	S46	D49N	49	Missense	distal	3	no	8.858	8.864	EPSD;PhosphoSitePlus	COSMIC	8.283	Up-regulation
Atypical_PIKK_DNAPK_PRKDC_ST	P04637	TP53	P78527	PRKDC	S46	M44I	44	Missense	proximal	-2	no	8.858	8.979	EPSD;PhosphoSitePlus	COSMIC	8.283	Up-regulation
Atypical_PIKK_DNAPK_PRKDC_ST	P04637	TP53	P78527	PRKDC	S46	Q52H	52	Missense	distal	6	no	8.858	8.848	EPSD;PhosphoSitePlus	COSMIC	8.283	Down-regulation
Atypical_PIKK_DNAPK_PRKDC_ST	P04637	TP53	P78527	PRKDC	S46	D49V	49	Missense	distal	3	no	8.858	8.235	EPSD;PhosphoSitePlus	COSMIC	8.283	Loss
Atypical_PIKK_DNAPK_PRKDC_ST	P04637	TP53	P78527	PRKDC	S46	A39V	39	Missense	distal	-7	no	8.858	7.936	EPSD;PhosphoSitePlus	COSMIC	8.283	Loss
Atypical_PIKK_DNAPK_PRKDC_ST	P04637	TP53	P78527	PRKDC	S46	A39S	39	Missense	distal	-7	no	8.858	8.910	EPSD;PhosphoSitePlus	COSMIC	8.283	Up-regulation
Atypical_PIKK_DNAPK_PRKDC_ST	P04637	TP53	P78527	PRKDC	S46	D42Y	42	Missense	distal	-4	no	8.858	8.651	EPSD;PhosphoSitePlus	COSMIC	8.283	Down-regulation
Atypical_PIKK_DNAPK_PRKDC_ST	P04637	TP53	P78527	PRKDC	S46	M44R	44	Missense	proximal	-2	no	8.858	8.850	EPSD;PhosphoSitePlus	COSMIC	8.283	Down-regulation
Atypical_PIKK_DNAPK_PRKDC_ST	P04637	TP53	P78527	PRKDC	S46	S46P	46	Missense	central	0	yes	8.858	0.000	EPSD;PhosphoSitePlus	COSMIC	8.283	Loss
Atypical_PIKK_DNAPK_PRKDC_ST	P04637	TP53	P78527	PRKDC	S46	M44V	44	Missense	proximal	-2	no	8.858	8.834	EPSD;PhosphoSitePlus	COSMIC	8.283	Down-regulation
Atypical_PIKK_DNAPK_PRKDC_ST	P04637	TP53	P78527	PRKDC	S46	L45P	45	Missense	proximal	-1	no	8.858	9.159	EPSD;PhosphoSitePlus	COSMIC	8.283	Up-regulation
Atypical_PIKK_DNAPK_PRKDC_ST	P04637	TP53	P78527	PRKDC	S46	M44T	44	Missense	proximal	-2	no	8.858	8.793	EPSD;PhosphoSitePlus	COSMIC	8.283	Down-regulation
Atypical_PIKK_DNAPK_PRKDC_ST	P04637	TP53	P78527	PRKDC	S46	A39T	39	Missense	distal	-7	no	8.858	8.591	EPSD;PhosphoSitePlus	COSMIC	8.283	Down-regulation
Atypical_PIKK_DNAPK_PRKDC_ST	P04637	TP53	P78527	PRKDC	S46	L43F	43	Missense	distal	-3	no	8.858	8.902	EPSD;PhosphoSitePlus	COSMIC	8.283	Up-regulation
Atypical_PIKK_DNAPK_PRKDC_ST	P04637	TP53	P78527	PRKDC	S46	D41H	41	Missense	distal	-5	no	8.858	9.003	EPSD;PhosphoSitePlus	COSMIC	8.283	Up-regulation
Atypical_PIKK_DNAPK_PRKDC_ST	P04637	TP53	P78527	PRKDC	S46	D49E	49	Missense	distal	3	no	8.858	9.064	EPSD;PhosphoSitePlus	COSMIC	8.283	Up-regulation
Atypical_PIKK_DNAPK_PRKDC_ST	P04637	TP53	P78527	PRKDC	S46	D49G	49	Missense	distal	3	no	8.858	8.562	EPSD;PhosphoSitePlus	COSMIC	8.283	Down-regulation
Atypical_PIKK_DNAPK_PRKDC_ST	P04637	TP53	P78527	PRKDC	S46	D48A	48	Missense	proximal	2	no	8.858	7.811	EPSD;PhosphoSitePlus	COSMIC	8.283	Loss
Atypical_PIKK_DNAPK_PRKDC_ST	P04637	TP53	P78527	PRKDC	S46	D48Y	48	Missense	proximal	2	no	8.858	6.909	EPSD;PhosphoSitePlus	COSMIC	8.283	Loss
Atypical_PIKK_DNAPK_PRKDC_ST	P04637	TP53	P78527	PRKDC	S46	D48E	48	Missense	proximal	2	no	8.858	8.471	EPSD;PhosphoSitePlus	COSMIC	8.283	Down-regulation
Atypical_PIKK_DNAPK_PRKDC_ST	P04637	TP53	P78527	PRKDC	S46	D49I	49	Missense	distal	3	no	8.858	7.881	EPSD;PhosphoSitePlus	COSMIC	8.283	Loss
Atypical_PIKK_DNAPK_PRKDC_ST	P04637	TP53	P78527	PRKDC	S46	D41E	41	Missense	distal	-5	no	8.858	9.042	EPSD;PhosphoSitePlus	COSMIC	8.283	Up-regulation
Atypical_PIKK_DNAPK_PRKDC_ST	P04637	TP53	P78527	PRKDC	S99	S99F	99	Missense	central	0	yes	10.676	0.000	EPSD	COSMIC	8.283	Loss
Atypical_PIKK_DNAPK_PRKDC_ST	P04637	TP53	P78527	PRKDC	S99	S96F	96	Missense	distal	-3	no	10.676	10.659	EPSD	COSMIC	8.283	Down-regulation
Atypical_PIKK_DNAPK_PRKDC_ST	P04637	TP53	P78527	PRKDC	S99	P98S	98	Missense	proximal	-1	no	10.676	10.337	EPSD	COSMIC;CCLE	8.283	Down-regulation
Atypical_PIKK_DNAPK_PRKDC_ST	P04637	TP53	P78527	PRKDC	S99	T102I	102	Missense	distal	3	no	10.676	10.055	EPSD	COSMIC	8.283	Down-regulation
Atypical_PIKK_DNAPK_PRKDC_ST	P04637	TP53	P78527	PRKDC	S99	S94P	94	Missense	distal	-5	no	10.676	10.305	EPSD	COSMIC	8.283	Down-regulation
Atypical_PIKK_DNAPK_PRKDC_ST	P04637	TP53	P78527	PRKDC	S99	K101R	101	Missense	proximal	2	no	10.676	10.744	EPSD	COSMIC	8.283	Up-regulation
Atypical_PIKK_DNAPK_PRKDC_ST	P04637	TP53	P78527	PRKDC	S99	S94T	94	Missense	distal	-5	no	10.676	10.435	EPSD	COSMIC	8.283	Down-regulation
Atypical_PIKK_DNAPK_PRKDC_ST	P04637	TP53	P78527	PRKDC	S99	P98L	98	Missense	proximal	-1	no	10.676	10.375	EPSD	COSMIC;GDSC;CCLE	8.283	Down-regulation
Atypical_PIKK_DNAPK_PRKDC_ST	P04637	TP53	P78527	PRKDC	S99	S95F	95	Missense	distal	-4	no	10.676	10.161	EPSD	COSMIC;CCLE	8.283	Down-regulation
Atypical_PIKK_DNAPK_PRKDC_ST	P04637	TP53	P78527	PRKDC	S99	S96C	96	Missense	distal	-3	no	10.676	10.440	EPSD	COSMIC	8.283	Down-regulation
Atypical_PIKK_DNAPK_PRKDC_ST	P04637	TP53	P78527	PRKDC	S99	S106I	106	Missense	distal	7	no	10.676	8.283	EPSD	COSMIC	8.283	Down-regulation
Atypical_PIKK_DNAPK_PRKDC_ST	P04637	TP53	P78527	PRKDC	S99	P98F	98	Missense	proximal	-1	no	10.676	10.600	EPSD	COSMIC	8.283	Down-regulation
Atypical_PIKK_DNAPK_PRKDC_ST	P04637	TP53	P78527	PRKDC	S99	T102P	102	Missense	distal	3	no	10.676	10.950	EPSD	COSMIC	8.283	Up-regulation
Atypical_PIKK_DNAPK_PRKDC_ST	P04637	TP53	P78527	PRKDC	S99	S94L	94	Missense	distal	-5	no	10.676	10.318	EPSD	COSMIC	8.283	Down-regulation
Atypical_PIKK_DNAPK_PRKDC_ST	P04637	TP53	P78527	PRKDC	S99	S96P	96	Missense	distal	-3	no	10.676	10.815	EPSD	COSMIC	8.283	Up-regulation
Atypical_PIKK_DNAPK_PRKDC_ST	P04637	TP53	P78527	PRKDC	S99	P98T	98	Missense	proximal	-1	no	10.676	9.851	EPSD	COSMIC	8.283	Down-regulation
Atypical_PIKK_DNAPK_PRKDC_ST	P04637	TP53	P78527	PRKDC	S99	S96Y	96	Missense	distal	-3	no	10.676	10.916	EPSD	COSMIC	8.283	Up-regulation
Atypical_PIKK_DNAPK_PRKDC_ST	P04637	TP53	P78527	PRKDC	S99	S99P	99	Missense	central	0	yes	10.676	0.000	EPSD	COSMIC	8.283	Loss
Atypical_PIKK_DNAPK_PRKDC_ST	P04637	TP53	P78527	PRKDC	S99	V97I	97	Missense	proximal	-2	no	10.676	10.821	EPSD	COSMIC	8.283	Up-regulation
Atypical_PIKK_DNAPK_PRKDC_ST	P04637	TP53	P78527	PRKDC	S99	Q104H	104	Missense	distal	5	no	10.676	10.507	EPSD	COSMIC	8.283	Down-regulation
Atypical_PIKK_DNAPK_PRKDC_ST	P04637	TP53	P78527	PRKDC	S99	L93M	93	Missense	distal	-6	no	10.676	10.441	EPSD	COSMIC	8.283	Down-regulation
Atypical_PIKK_DNAPK_PRKDC_ST	P04637	TP53	P78527	PRKDC	S99	K101N	101	Missense	proximal	2	no	10.676	11.097	EPSD	COSMIC	8.283	Up-regulation
Atypical_PIKK_DNAPK_PRKDC_ST	P04637	TP53	P78527	PRKDC	S99	V97A	97	Missense	proximal	-2	no	10.676	10.555	EPSD	COSMIC	8.283	Down-regulation
Atypical_PIKK_DNAPK_PRKDC_ST	P04637	TP53	P78527	PRKDC	S99	P92A	92	Missense	distal	-7	no	10.676	11.274	EPSD	COSMIC	8.283	Up-regulation
Atypical_PIKK_DNAPK_PRKDC_ST	P04637	TP53	P78527	PRKDC	S99	Q104L	104	Missense	distal	5	no	10.676	10.483	EPSD	COSMIC	8.283	Down-regulation
Atypical_PIKK_DNAPK_PRKDC_ST	P04637	TP53	P78527	PRKDC	S99	P92L	92	Missense	distal	-7	no	10.676	10.859	EPSD	COSMIC	8.283	Up-regulation
Atypical_PIKK_DNAPK_PRKDC_ST	P04637	TP53	P78527	PRKDC	S99	L93P	93	Missense	distal	-6	no	10.676	10.557	EPSD	COSMIC	8.283	Down-regulation
Atypical_PIKK_DNAPK_PRKDC_ST	P04637	TP53	P78527	PRKDC	S99	L93F	93	Missense	distal	-6	no	10.676	10.430	EPSD	COSMIC	8.283	Down-regulation
Atypical_PIKK_DNAPK_PRKDC_ST	P04637	TP53	P78527	PRKDC	S99	L93H	93	Missense	distal	-6	no	10.676	10.778	EPSD	COSMIC	8.283	Up-regulation
Atypical_PIKK_DNAPK_PRKDC_ST	P04637	TP53	P78527	PRKDC	S99	S95Y	95	Missense	distal	-4	no	10.676	10.412	EPSD	COSMIC	8.283	Down-regulation
Atypical_PIKK_DNAPK_PRKDC_ST	P04637	TP53	P78527	PRKDC	S106	Y107Q	107	Missense	proximal	1	no	6.786	10.782	EPSD	COSMIC	8.283	Gain
Atypical_PIKK_DNAPK_PRKDC_ST	P04637	TP53	P78527	PRKDC	S106	G108D	108	Missense	proximal	2	no	6.786	8.582	EPSD	COSMIC	8.283	Gain
Atypical_PIKK_DNAPK_PRKDC_ST	P04637	TP53	P78527	PRKDC	T125	C124F	124	Missense	proximal	-1	no	7.932	8.877	EPSD	COSMIC	8.283	Gain
Atypical_PIKK_DNAPK_PRKDC_ST	P04637	TP53	P78527	PRKDC	T125	C124S	124	Missense	proximal	-1	no	7.932	8.613	EPSD	COSMIC	8.283	Gain
Atypical_PIKK_DNAPK_PRKDC_ST	P04637	TP53	P78527	PRKDC	T125	C124L	124	Missense	proximal	-1	no	7.932	8.652	EPSD	COSMIC	8.283	Gain
Atypical_PIKK_DNAPK_PRKDC_ST	P04637	TP53	P78527	PRKDC	S183	D184Y	184	Missense	proximal	1	no	7.239	9.700	EPSD	COSMIC	8.283	Gain
Atypical_PIKK_DNAPK_PRKDC_ST	P04637	TP53	P78527	PRKDC	S215	V217A	217	Missense	proximal	2	no	6.872	8.503	EPSD	COSMIC	8.283	Gain
Atypical_PIKK_DNAPK_PRKDC_ST	P04637	TP53	P78527	PRKDC	S215	V217E	217	Missense	proximal	2	no	6.872	9.164	EPSD	COSMIC	8.283	Gain
Atypical_PIKK_DNAPK_PRKDC_ST	P04637	TP53	P78527	PRKDC	S269	G262H	262	Missense	distal	-7	no	7.664	8.358	EPSD	COSMIC	8.283	Gain
Atypical_PIKK_DNAPK_PRKDC_ST	P04637	TP53	P78527	PRKDC	S269	F270Y	270	Missense	proximal	1	no	7.664	10.527	EPSD	COSMIC	8.283	Gain
Atypical_PIKK_DNAPK_PRKDC_ST	Q9UGP5	POLL	P78527	PRKDC	S167	T173A	173	Missense	distal	6	no	8.825	8.830	EPSD	COSMIC	8.283	Up-regulation
Atypical_PIKK_DNAPK_PRKDC_ST	Q9UGP5	POLL	P78527	PRKDC	S167	T173P	173	Missense	distal	6	no	8.825	8.839	EPSD	COSMIC	8.283	Up-regulation
Atypical_PIKK_DNAPK_PRKDC_ST	Q9UGP5	POLL	P78527	PRKDC	S167	L162M	162	Missense	distal	-5	no	8.825	8.714	EPSD	COSMIC	8.283	Down-regulation
Atypical_PIKK_DNAPK_PRKDC_ST	Q9UGP5	POLL	P78527	PRKDC	T204	A198T	198	Missense	distal	-6	no	11.288	10.898	PhosphoSitePlus	COSMIC	8.283	Down-regulation
Atypical_PIKK_DNAPK_PRKDC_ST	Q9UGP5	POLL	P78527	PRKDC	T204	S207L	207	Missense	distal	3	no	11.288	10.907	PhosphoSitePlus	COSMIC	8.283	Down-regulation
Atypical_PIKK_DNAPK_PRKDC_ST	Q9UGP5	POLL	P78527	PRKDC	T204	S199N	199	Missense	distal	-5	no	11.288	11.134	PhosphoSitePlus	COSMIC	8.283	Down-regulation
Atypical_PIKK_DNAPK_PRKDC_ST	Q9UGP5	POLL	P78527	PRKDC	S246	H252D	252	Missense	distal	6	no	10.994	10.997	EPSD	COSMIC	8.283	Up-regulation
Atypical_PIKK_DNAPK_PRKDC_ST	Q9UGP5	POLL	P78527	PRKDC	S246	A249V	249	Missense	distal	3	no	10.994	10.471	EPSD	COSMIC;CCLE	8.283	Down-regulation
Atypical_PIKK_DNAPK_PRKDC_ST	Q9UGP5	POLL	P78527	PRKDC	S246	N251S	251	Missense	distal	5	no	10.994	11.069	EPSD	COSMIC	8.283	Up-regulation
Atypical_PIKK_DNAPK_PRKDC_ST	Q9UGP5	POLL	P78527	PRKDC	S526	A520S	520	Missense	distal	-6	no	9.461	9.418	EPSD	COSMIC	8.283	Down-regulation
Atypical_PIKK_DNAPK_PRKDC_ST	P23025	XPA	P78527	PRKDC	S196	A199V	199	Missense	distal	3	no	13.509	12.986	PhosphoSitePlus;EPSD	COSMIC	8.283	Down-regulation
Atypical_PIKK_DNAPK_PRKDC_ST	P23025	XPA	P78527	PRKDC	S196	E202K	202	Missense	distal	6	no	13.509	13.478	PhosphoSitePlus;EPSD	COSMIC	8.283	Down-regulation
Atypical_PIKK_DNAPK_PRKDC_ST	P23025	XPA	P78527	PRKDC	S196	Q197R	197	Missense	proximal	1	no	13.509	3.094	PhosphoSitePlus;EPSD	COSMIC	8.283	Loss
Atypical_PIKK_DNAPK_PRKDC_ST	P17936	IGFBP3	P78527	PRKDC	T14	T7M	7	Missense	distal	-7	no	8.456	8.130	EPSD	COSMIC	8.283	Loss
Atypical_PIKK_DNAPK_PRKDC_ST	P17936	IGFBP3	P78527	PRKDC	T14	A10S	10	Missense	distal	-4	no	8.456	8.530	EPSD	COSMIC;CCLE	8.283	Up-regulation
Atypical_PIKK_DNAPK_PRKDC_ST	P17936	IGFBP3	P78527	PRKDC	S140	E141K	141	Missense	proximal	1	no	9.036	5.566	EPSD	COSMIC	8.283	Loss
Atypical_PIKK_DNAPK_PRKDC_ST	P17936	IGFBP3	P78527	PRKDC	S140	S140L	140	Missense	central	0	yes	9.036	0.000	EPSD	COSMIC	8.283	Loss
Atypical_PIKK_DNAPK_PRKDC_ST	P17936	IGFBP3	P78527	PRKDC	S140	E142K	142	Missense	proximal	2	no	9.036	7.060	EPSD	COSMIC	8.283	Loss
Atypical_PIKK_DNAPK_PRKDC_ST	P17936	IGFBP3	P78527	PRKDC	S140	R144C	144	Missense	distal	4	no	9.036	9.031	EPSD	COSMIC	8.283	Down-regulation
Atypical_PIKK_DNAPK_PRKDC_ST	P17936	IGFBP3	P78527	PRKDC	S140	G135E	135	Missense	distal	-5	no	9.036	9.357	EPSD	COSMIC	8.283	Up-regulation
Atypical_PIKK_DNAPK_PRKDC_ST	P17936	IGFBP3	P78527	PRKDC	S140	G147S	147	Missense	distal	7	no	9.036	9.744	EPSD	COSMIC	8.283	Up-regulation
Atypical_PIKK_DNAPK_PRKDC_ST	P17936	IGFBP3	P78527	PRKDC	S140	A146T	146	Missense	distal	6	no	9.036	9.031	EPSD	COSMIC	8.283	Down-regulation
Atypical_PIKK_DNAPK_PRKDC_ST	P17936	IGFBP3	P78527	PRKDC	S140	R144H	144	Missense	distal	4	no	9.036	9.057	EPSD	COSMIC	8.283	Up-regulation
Atypical_PIKK_DNAPK_PRKDC_ST	P17936	IGFBP3	P78527	PRKDC	S145	R144H	144	Missense	proximal	-1	no	7.392	8.445	EPSD	COSMIC	8.283	Gain
Atypical_PIKK_DNAPK_PRKDC_ST	P17936	IGFBP3	P78527	PRKDC	S148	R144H	144	Missense	distal	-4	no	7.913	8.365	EPSD	COSMIC	8.283	Gain
Atypical_PIKK_DNAPK_PRKDC_ST	P17936	IGFBP3	P78527	PRKDC	S151	H158P	158	Missense	distal	7	no	10.147	9.996	EPSD	COSMIC	8.283	Down-regulation
Atypical_PIKK_DNAPK_PRKDC_ST	P17936	IGFBP3	P78527	PRKDC	S151	S155P	155	Missense	distal	4	no	10.147	10.121	EPSD	COSMIC	8.283	Down-regulation
Atypical_PIKK_DNAPK_PRKDC_ST	P17936	IGFBP3	P78527	PRKDC	S151	S153P	153	Missense	proximal	2	no	10.147	9.917	EPSD	COSMIC	8.283	Down-regulation
Atypical_PIKK_DNAPK_PRKDC_ST	P17936	IGFBP3	P78527	PRKDC	S151	V154I	154	Missense	distal	3	no	10.147	9.794	EPSD	COSMIC	8.283	Down-regulation
Atypical_PIKK_DNAPK_PRKDC_ST	P17936	IGFBP3	P78527	PRKDC	S151	P152Q	152	Missense	proximal	1	no	10.147	14.628	EPSD	COSMIC	8.283	Up-regulation
Atypical_PIKK_DNAPK_PRKDC_ST	P17936	IGFBP3	P78527	PRKDC	S151	R144C	144	Missense	distal	-7	no	10.147	9.654	EPSD	COSMIC	8.283	Down-regulation
Atypical_PIKK_DNAPK_PRKDC_ST	P17936	IGFBP3	P78527	PRKDC	S151	T157K	157	Missense	distal	6	no	10.147	10.144	EPSD	COSMIC	8.283	Down-regulation
Atypical_PIKK_DNAPK_PRKDC_ST	P17936	IGFBP3	P78527	PRKDC	S151	G147S	147	Missense	distal	-4	no	10.147	10.592	EPSD	COSMIC	8.283	Up-regulation
Atypical_PIKK_DNAPK_PRKDC_ST	P17936	IGFBP3	P78527	PRKDC	S151	S153Y	153	Missense	proximal	2	no	10.147	9.218	EPSD	COSMIC	8.283	Down-regulation
Atypical_PIKK_DNAPK_PRKDC_ST	P17936	IGFBP3	P78527	PRKDC	S151	A146T	146	Missense	distal	-5	no	10.147	10.042	EPSD	COSMIC	8.283	Down-regulation
Atypical_PIKK_DNAPK_PRKDC_ST	P17936	IGFBP3	P78527	PRKDC	S151	R144H	144	Missense	distal	-7	no	10.147	10.964	EPSD	COSMIC	8.283	Up-regulation
Atypical_PIKK_DNAPK_PRKDC_ST	P17936	IGFBP3	P78527	PRKDC	S183	Y186C	186	Missense	distal	3	no	12.628	12.421	PhosphoSitePlus	COSMIC	8.283	Down-regulation
Atypical_PIKK_DNAPK_PRKDC_ST	P17936	IGFBP3	P78527	PRKDC	S183	R185H	185	Missense	proximal	2	no	12.628	13.524	PhosphoSitePlus	COSMIC	8.283	Up-regulation
Atypical_PIKK_DNAPK_PRKDC_ST	P17936	IGFBP3	P78527	PRKDC	S183	R185C	185	Missense	proximal	2	no	12.628	12.754	PhosphoSitePlus	COSMIC	8.283	Up-regulation
Atypical_PIKK_DNAPK_PRKDC_ST	P17936	IGFBP3	P78527	PRKDC	S183	K176N	176	Missense	distal	-7	no	12.628	12.521	PhosphoSitePlus	COSMIC	8.283	Down-regulation
Atypical_PIKK_DNAPK_PRKDC_ST	P17936	IGFBP3	P78527	PRKDC	S183	R185Q	185	Missense	proximal	2	no	12.628	13.980	PhosphoSitePlus	COSMIC	8.283	Up-regulation
Atypical_PIKK_DNAPK_PRKDC_ST	P17936	IGFBP3	P78527	PRKDC	S183	R185W	185	Missense	proximal	2	no	12.628	11.879	PhosphoSitePlus	COSMIC	8.283	Down-regulation
Atypical_PIKK_DNAPK_PRKDC_ST	P17936	IGFBP3	P78527	PRKDC	S192	Y186C	186	Missense	distal	-6	no	12.569	12.106	EPSD	COSMIC	8.283	Down-regulation
Atypical_PIKK_DNAPK_PRKDC_ST	P17936	IGFBP3	P78527	PRKDC	S192	T197I	197	Missense	distal	5	no	12.569	12.372	EPSD	COSMIC	8.283	Down-regulation
Atypical_PIKK_DNAPK_PRKDC_ST	P17936	IGFBP3	P78527	PRKDC	S192	R185H	185	Missense	distal	-7	no	12.569	13.386	EPSD	COSMIC	8.283	Up-regulation
Atypical_PIKK_DNAPK_PRKDC_ST	P17936	IGFBP3	P78527	PRKDC	S192	R185C	185	Missense	distal	-7	no	12.569	12.076	EPSD	COSMIC	8.283	Down-regulation
Atypical_PIKK_DNAPK_PRKDC_ST	P17936	IGFBP3	P78527	PRKDC	S192	N199S	199	Missense	distal	7	no	12.569	13.127	EPSD	COSMIC	8.283	Up-regulation
Atypical_PIKK_DNAPK_PRKDC_ST	P17936	IGFBP3	P78527	PRKDC	S192	D196N	196	Missense	distal	4	no	12.569	12.593	EPSD	COSMIC	8.283	Up-regulation
Atypical_PIKK_DNAPK_PRKDC_ST	P17936	IGFBP3	P78527	PRKDC	S192	R185Q	185	Missense	distal	-7	no	12.569	13.383	EPSD	COSMIC	8.283	Up-regulation
Atypical_PIKK_DNAPK_PRKDC_ST	P17936	IGFBP3	P78527	PRKDC	S192	R185W	185	Missense	distal	-7	no	12.569	11.761	EPSD	COSMIC	8.283	Down-regulation
Atypical_PIKK_DNAPK_PRKDC_ST	P17936	IGFBP3	P78527	PRKDC	T197	S201F	201	Missense	distal	4	no	13.460	13.435	EPSD	COSMIC;CCLE	8.283	Down-regulation
Atypical_PIKK_DNAPK_PRKDC_ST	P17936	IGFBP3	P78527	PRKDC	T197	T197I	197	Missense	central	0	yes	13.460	0.000	EPSD	COSMIC	8.283	Loss
Atypical_PIKK_DNAPK_PRKDC_ST	P17936	IGFBP3	P78527	PRKDC	T197	N199S	199	Missense	proximal	2	no	13.460	14.383	EPSD	COSMIC	8.283	Up-regulation
Atypical_PIKK_DNAPK_PRKDC_ST	P17936	IGFBP3	P78527	PRKDC	T197	S202F	202	Missense	distal	5	no	13.460	13.415	EPSD	COSMIC	8.283	Down-regulation
Atypical_PIKK_DNAPK_PRKDC_ST	P17936	IGFBP3	P78527	PRKDC	T197	F200L	200	Missense	distal	3	no	13.460	13.364	EPSD	COSMIC	8.283	Down-regulation
Atypical_PIKK_DNAPK_PRKDC_ST	P17936	IGFBP3	P78527	PRKDC	T197	D196N	196	Missense	proximal	-1	no	13.460	12.719	EPSD	COSMIC	8.283	Down-regulation
Atypical_PIKK_DNAPK_PRKDC_ST	P17936	IGFBP3	P78527	PRKDC	S231	P238H	238	Missense	distal	7	no	9.047	9.199	EPSD	COSMIC	8.283	Up-regulation
Atypical_PIKK_DNAPK_PRKDC_ST	P17936	IGFBP3	P78527	PRKDC	S231	L230V	230	Missense	proximal	-1	no	9.047	8.107	EPSD	COSMIC	8.283	Loss
Atypical_PIKK_DNAPK_PRKDC_ST	P17936	IGFBP3	P78527	PRKDC	S231	N228S	228	Missense	distal	-3	no	9.047	8.869	EPSD	COSMIC	8.283	Down-regulation
Atypical_PIKK_DNAPK_PRKDC_ST	P17936	IGFBP3	P78527	PRKDC	S231	P238T	238	Missense	distal	7	no	9.047	8.327	EPSD	COSMIC	8.283	Down-regulation
Atypical_PIKK_DNAPK_PRKDC_ST	P17936	IGFBP3	P78527	PRKDC	S231	P238L	238	Missense	distal	7	no	9.047	8.420	EPSD	COSMIC	8.283	Down-regulation
Atypical_PIKK_DNAPK_PRKDC_ST	P17936	IGFBP3	P78527	PRKDC	S231	V229M	229	Missense	proximal	-2	no	9.047	9.072	EPSD	COSMIC	8.283	Up-regulation
Atypical_PIKK_DNAPK_PRKDC_ST	P17936	IGFBP3	P78527	PRKDC	S231	P232H	232	Missense	proximal	1	no	9.047	3.193	EPSD	COSMIC	8.283	Loss
Atypical_PIKK_DNAPK_PRKDC_ST	P17936	IGFBP3	P78527	PRKDC	S231	P232S	232	Missense	proximal	1	no	9.047	4.692	EPSD	COSMIC	8.283	Loss
Atypical_PIKK_DNAPK_PRKDC_ST	Q9H9Q4	NHEJ1	P78527	PRKDC	S55	V49G	49	Missense	distal	-6	no	10.966	11.384	EPSD;PhosphoSitePlus	COSMIC	8.283	Up-regulation
Atypical_PIKK_DNAPK_PRKDC_ST	Q9H9Q4	NHEJ1	P78527	PRKDC	S55	R57L	57	Missense	proximal	2	no	10.966	11.053	EPSD;PhosphoSitePlus	COSMIC	8.283	Up-regulation
Atypical_PIKK_DNAPK_PRKDC_ST	Q9H9Q4	NHEJ1	P78527	PRKDC	S55	V54A	54	Missense	proximal	-1	no	10.966	12.278	EPSD;PhosphoSitePlus	COSMIC	8.283	Up-regulation
Atypical_PIKK_DNAPK_PRKDC_ST	Q9H9Q4	NHEJ1	P78527	PRKDC	S132	R137C	137	Missense	distal	5	no	10.403	10.408	EPSD;PhosphoSitePlus	COSMIC	8.283	Up-regulation
Atypical_PIKK_DNAPK_PRKDC_ST	Q9H9Q4	NHEJ1	P78527	PRKDC	S251	Q256H	256	Missense	distal	5	no	11.994	11.824	EPSD;PhosphoSitePlus	COSMIC	8.283	Down-regulation
Atypical_PIKK_DNAPK_PRKDC_ST	Q9H9Q4	NHEJ1	P78527	PRKDC	S263	P270S	270	Missense	distal	7	no	10.763	10.890	EPSD;PhosphoSitePlus	COSMIC	8.283	Up-regulation
Atypical_PIKK_DNAPK_PRKDC_ST	Q9H9Q4	NHEJ1	P78527	PRKDC	S263	Q256H	256	Missense	distal	-7	no	10.763	10.766	EPSD;PhosphoSitePlus	COSMIC	8.283	Up-regulation
Atypical_PIKK_DNAPK_PRKDC_ST	Q9H9Q4	NHEJ1	P78527	PRKDC	T266	P270S	270	Missense	distal	4	no	10.476	10.502	PhosphoSitePlus;EPSD	COSMIC	8.283	Up-regulation
Atypical_PIKK_DNAPK_PRKDC_ST	Q9H9Q4	NHEJ1	P78527	PRKDC	S268	P270S	270	Missense	proximal	2	no	8.086	8.317	EPSD	COSMIC	8.283	Gain
Atypical_PIKK_DNAPK_PRKDC_ST	P07900	HSP90AA1	P78527	PRKDC	T5	E4G	4	Missense	proximal	-1	no	13.034	11.766	EPSD;PhosphoSitePlus	COSMIC	8.283	Down-regulation
Atypical_PIKK_DNAPK_PRKDC_ST	P07900	HSP90AA1	P78527	PRKDC	T7	E4G	4	Missense	distal	-3	no	15.903	15.622	PhosphoSitePlus;EPSD	COSMIC	8.283	Down-regulation
Atypical_PIKK_DNAPK_PRKDC_ST	P07900	HSP90AA1	P78527	PRKDC	S252	E248Q	248	Missense	distal	-4	no	9.472	9.617	EPSD	COSMIC;CCLE	8.283	Up-regulation
Atypical_PIKK_DNAPK_PRKDC_ST	P07900	HSP90AA1	P78527	PRKDC	S252	P256R	256	Missense	distal	4	no	9.472	9.460	EPSD	COSMIC	8.283	Down-regulation
Atypical_PIKK_DNAPK_PRKDC_ST	P07900	HSP90AA1	P78527	PRKDC	S453	H450L	450	Missense	distal	-3	no	10.301	10.095	EPSD	COSMIC	8.283	Down-regulation
Atypical_PIKK_DNAPK_PRKDC_ST	P07900	HSP90AA1	P78527	PRKDC	S453	D452V	452	Missense	proximal	-1	no	10.301	8.649	EPSD	COSMIC	8.283	Down-regulation
Atypical_PIKK_DNAPK_PRKDC_ST	P07900	HSP90AA1	P78527	PRKDC	S453	S453C	453	Missense	central	0	yes	10.301	0.000	EPSD	COSMIC	8.283	Loss
Atypical_PIKK_DNAPK_PRKDC_ST	P07900	HSP90AA1	P78527	PRKDC	S505	N504D	504	Missense	proximal	-1	no	7.608	8.349	EPSD	COSMIC;CCLE	8.283	Gain
Atypical_PIKK_DNAPK_PRKDC_ST	P07900	HSP90AA1	P78527	PRKDC	S677	A670V	670	Missense	distal	-7	no	11.015	10.093	EPSD	COSMIC	8.283	Down-regulation
Atypical_PIKK_DNAPK_PRKDC_ST	P13010	XRCC5	P78527	PRKDC	S379	L380Q	380	Missense	proximal	1	no	7.285	11.826	EPSD	COSMIC	8.283	Gain
Atypical_PIKK_DNAPK_PRKDC_ST	P13010	XRCC5	P78527	PRKDC	S580	V586A	586	Missense	distal	6	no	9.864	9.877	PhosphoSitePlus;EPSD	COSMIC	8.283	Up-regulation
Atypical_PIKK_DNAPK_PRKDC_ST	P13010	XRCC5	P78527	PRKDC	S712	P711Q	711	Missense	proximal	-1	no	8.864	9.315	EPSD	COSMIC	8.283	Up-regulation
Atypical_PIKK_DNAPK_PRKDC_ST	P13010	XRCC5	P78527	PRKDC	S712	A716T	716	Missense	distal	4	no	8.864	8.804	EPSD	COSMIC	8.283	Down-regulation
Atypical_PIKK_DNAPK_PRKDC_ST	P13010	XRCC5	P78527	PRKDC	T715	P711Q	711	Missense	distal	-4	no	8.413	8.918	EPSD;PhosphoSitePlus	COSMIC	8.283	Up-regulation
Atypical_PIKK_DNAPK_PRKDC_ST	P13010	XRCC5	P78527	PRKDC	T715	A716T	716	Missense	proximal	1	no	8.413	3.172	EPSD;PhosphoSitePlus	COSMIC	8.283	Loss
Atypical_PIKK_DNAPK_PRKDC_ST	P46527	CDKN1B	P78527	PRKDC	S10	R5L	5	Missense	distal	-5	no	9.159	9.272	EPSD	COSMIC	8.283	Up-regulation
Atypical_PIKK_DNAPK_PRKDC_ST	P46527	CDKN1B	P78527	PRKDC	S10	E14K	14	Missense	distal	4	no	9.159	9.146	EPSD	COSMIC	8.283	Down-regulation
Atypical_PIKK_DNAPK_PRKDC_ST	P46527	CDKN1B	P78527	PRKDC	S10	M16T	16	Missense	distal	6	no	9.159	9.172	EPSD	COSMIC	8.283	Up-regulation
Atypical_PIKK_DNAPK_PRKDC_ST	P46527	CDKN1B	P78527	PRKDC	S10	N3D	3	Missense	distal	-7	no	9.159	9.308	EPSD	COSMIC	8.283	Up-regulation
Atypical_PIKK_DNAPK_PRKDC_ST	P46527	CDKN1B	P78527	PRKDC	S10	P11S	11	Missense	proximal	1	no	9.159	4.804	EPSD	COSMIC	8.283	Loss
Atypical_PIKK_DNAPK_PRKDC_ST	P46527	CDKN1B	P78527	PRKDC	S10	S12N	12	Missense	proximal	2	no	9.159	8.236	EPSD	COSMIC	8.283	Loss
Atypical_PIKK_DNAPK_PRKDC_ST	P46527	CDKN1B	P78527	PRKDC	S10	D17E	17	Missense	distal	7	no	9.159	9.069	EPSD	COSMIC	8.283	Down-regulation
Atypical_PIKK_DNAPK_PRKDC_ST	P46527	CDKN1B	P78527	PRKDC	S12	R5L	5	Missense	distal	-7	no	10.753	10.952	EPSD	COSMIC	8.283	Up-regulation
Atypical_PIKK_DNAPK_PRKDC_ST	P46527	CDKN1B	P78527	PRKDC	S12	E14K	14	Missense	proximal	2	no	10.753	8.776	EPSD	COSMIC	8.283	Down-regulation
Atypical_PIKK_DNAPK_PRKDC_ST	P46527	CDKN1B	P78527	PRKDC	S12	M16T	16	Missense	distal	4	no	10.753	10.741	EPSD	COSMIC	8.283	Down-regulation
Atypical_PIKK_DNAPK_PRKDC_ST	P46527	CDKN1B	P78527	PRKDC	S12	P11S	11	Missense	proximal	-1	no	10.753	10.413	EPSD	COSMIC	8.283	Down-regulation
Atypical_PIKK_DNAPK_PRKDC_ST	P46527	CDKN1B	P78527	PRKDC	S12	A18V	18	Missense	distal	6	no	10.753	10.739	EPSD	COSMIC	8.283	Down-regulation
Atypical_PIKK_DNAPK_PRKDC_ST	P46527	CDKN1B	P78527	PRKDC	S12	S12N	12	Missense	central	0	yes	10.753	0.000	EPSD	COSMIC	8.283	Loss
Atypical_PIKK_DNAPK_PRKDC_ST	P46527	CDKN1B	P78527	PRKDC	S12	D17E	17	Missense	distal	5	no	10.753	10.784	EPSD	COSMIC	8.283	Up-regulation
Atypical_PIKK_DNAPK_PRKDC_ST	P46527	CDKN1B	P78527	PRKDC	S106	Q107R	107	Missense	proximal	1	no	12.199	1.785	EPSD	COSMIC	8.283	Loss
Atypical_PIKK_DNAPK_PRKDC_ST	P46527	CDKN1B	P78527	PRKDC	S106	D108N	108	Missense	proximal	2	no	12.199	10.256	EPSD	COSMIC	8.283	Down-regulation
Atypical_PIKK_DNAPK_PRKDC_ST	P46527	CDKN1B	P78527	PRKDC	S110	Q107R	107	Missense	distal	-3	no	8.649	8.124	EPSD	COSMIC	8.283	Loss
Atypical_PIKK_DNAPK_PRKDC_ST	P46527	CDKN1B	P78527	PRKDC	S110	D108N	108	Missense	proximal	-2	no	8.649	8.672	EPSD	COSMIC	8.283	Up-regulation
Atypical_PIKK_DNAPK_PRKDC_ST	P46527	CDKN1B	P78527	PRKDC	S110	A116T	116	Missense	distal	6	no	8.649	8.644	EPSD	COSMIC	8.283	Down-regulation
Atypical_PIKK_DNAPK_PRKDC_ST	P46527	CDKN1B	P78527	PRKDC	S140	P133T	133	Missense	distal	-7	no	14.217	14.547	PhosphoSitePlus	COSMIC	8.283	Up-regulation
Atypical_PIKK_DNAPK_PRKDC_ST	P46527	CDKN1B	P78527	PRKDC	S140	P137S	137	Missense	distal	-3	no	14.217	14.079	PhosphoSitePlus	COSMIC	8.283	Down-regulation
Atypical_PIKK_DNAPK_PRKDC_ST	P46527	CDKN1B	P78527	PRKDC	S140	S140R	140	Missense	central	0	yes	14.217	0.000	PhosphoSitePlus	COSMIC	8.283	Loss
Atypical_PIKK_DNAPK_PRKDC_ST	P46527	CDKN1B	P78527	PRKDC	S140	D136G	136	Missense	distal	-4	no	14.217	13.829	PhosphoSitePlus	COSMIC;GDSC	8.283	Down-regulation
Atypical_PIKK_DNAPK_PRKDC_ST	P46527	CDKN1B	P78527	PRKDC	S140	E146V	146	Missense	distal	6	no	14.217	14.181	PhosphoSitePlus	COSMIC	8.283	Down-regulation
Atypical_PIKK_DNAPK_PRKDC_ST	P46527	CDKN1B	P78527	PRKDC	S178	V184L	184	Missense	distal	6	no	9.090	9.101	EPSD	COSMIC	8.283	Up-regulation
Atypical_PIKK_DNAPK_PRKDC_ST	P46527	CDKN1B	P78527	PRKDC	S178	G182D	182	Missense	distal	4	no	9.090	9.092	EPSD	COSMIC	8.283	Up-regulation
Atypical_PIKK_DNAPK_PRKDC_ST	P46527	CDKN1B	P78527	PRKDC	S183	V184L	184	Missense	proximal	1	no	7.341	8.839	EPSD	COSMIC	8.283	Gain
Atypical_PIKK_DNAPK_PRKDC_ST	P46527	CDKN1B	P78527	PRKDC	S183	G182D	182	Missense	proximal	-1	no	7.341	8.354	EPSD	COSMIC	8.283	Gain
Atypical_PIKK_DNAPK_PRKDC_ST	P46527	CDKN1B	P78527	PRKDC	T187	V184L	184	Missense	distal	-3	no	9.114	9.299	EPSD	COSMIC	8.283	Up-regulation
Atypical_PIKK_DNAPK_PRKDC_ST	P46527	CDKN1B	P78527	PRKDC	T187	G182D	182	Missense	distal	-5	no	9.114	9.252	EPSD	COSMIC	8.283	Up-regulation
Atypical_PIKK_DNAPK_PRKDC_ST	P46527	CDKN1B	P78527	PRKDC	T187	R194K	194	Missense	distal	7	no	9.114	9.477	EPSD	COSMIC	8.283	Up-regulation
Atypical_PIKK_DNAPK_PRKDC_ST	P19838	NFKB1	P78527	PRKDC	S20	L21M	21	Missense	proximal	1	no	8.943	1.673	PhosphoSitePlus	COSMIC	8.283	Loss
Atypical_PIKK_DNAPK_PRKDC_ST	P19838	NFKB1	P78527	PRKDC	S371	P368L	368	Missense	distal	-3	no	8.314	8.114	EPSD	COSMIC	8.283	Loss
Atypical_PIKK_DNAPK_PRKDC_ST	P19838	NFKB1	P78527	PRKDC	S371	L366F	366	Missense	distal	-5	no	8.314	8.263	EPSD	COSMIC	8.283	Loss
Atypical_PIKK_DNAPK_PRKDC_ST	P19838	NFKB1	P78527	PRKDC	S371	G375S	375	Missense	distal	4	no	8.314	8.321	EPSD	COSMIC	8.283	Up-regulation
Atypical_PIKK_DNAPK_PRKDC_ST	P19838	NFKB1	P78527	PRKDC	S371	G376S	376	Missense	distal	5	no	8.314	8.430	EPSD	COSMIC;CCLE	8.283	Up-regulation
Atypical_PIKK_DNAPK_PRKDC_ST	P19838	NFKB1	P78527	PRKDC	S899	P905S	905	Missense	distal	6	no	12.719	12.709	EPSD	COSMIC	8.283	Down-regulation
Atypical_PIKK_DNAPK_PRKDC_ST	P19838	NFKB1	P78527	PRKDC	S899	S893P	893	Missense	distal	-6	no	12.719	12.354	EPSD	COSMIC	8.283	Down-regulation
Atypical_PIKK_DNAPK_PRKDC_ST	P19838	NFKB1	P78527	PRKDC	S899	S893Y	893	Missense	distal	-6	no	12.719	12.324	EPSD	COSMIC	8.283	Down-regulation
Atypical_PIKK_DNAPK_PRKDC_ST	P19838	NFKB1	P78527	PRKDC	S899	S893F	893	Missense	distal	-6	no	12.719	12.227	EPSD	COSMIC	8.283	Down-regulation
Atypical_PIKK_DNAPK_PRKDC_ST	P19838	NFKB1	P78527	PRKDC	S907	S910F	910	Missense	distal	3	no	9.433	9.147	EPSD	COSMIC	8.283	Down-regulation
Atypical_PIKK_DNAPK_PRKDC_ST	P19838	NFKB1	P78527	PRKDC	S907	P905S	905	Missense	proximal	-2	no	9.433	9.408	EPSD	COSMIC	8.283	Down-regulation
Atypical_PIKK_DNAPK_PRKDC_ST	P19838	NFKB1	P78527	PRKDC	S947	S947L	947	Missense	central	0	yes	9.048	0.000	EPSD	COSMIC	8.283	Loss
Atypical_PIKK_DNAPK_PRKDC_ST	P19838	NFKB1	P78527	PRKDC	S947	L951F	951	Missense	distal	4	no	9.048	9.042	EPSD	COSMIC	8.283	Down-regulation
Atypical_PIKK_DNAPK_PRKDC_ST	Q00839	HNRNPU	P78527	PRKDC	S326	K333Q	333	Missense	distal	7	no	7.962	8.870	EPSD	COSMIC	8.283	Gain
Atypical_PIKK_DNAPK_PRKDC_ST	Q00839	HNRNPU	P78527	PRKDC	S382	T388S	388	Missense	distal	6	no	9.953	9.957	EPSD	COSMIC	8.283	Up-regulation
Atypical_PIKK_DNAPK_PRKDC_ST	Q00839	HNRNPU	P78527	PRKDC	S382	T388A	388	Missense	distal	6	no	9.953	9.958	EPSD	COSMIC	8.283	Up-regulation
Atypical_PIKK_DNAPK_PRKDC_ST	Q00839	HNRNPU	P78527	PRKDC	T554	K551N	551	Missense	distal	-3	no	9.919	10.197	EPSD	COSMIC;CCLE	8.283	Up-regulation
Atypical_PIKK_DNAPK_PRKDC_ST	Q00839	HNRNPU	P78527	PRKDC	T554	A559G	559	Missense	distal	5	no	9.919	9.782	EPSD	COSMIC	8.283	Down-regulation
Atypical_PIKK_DNAPK_PRKDC_ST	Q00839	HNRNPU	P78527	PRKDC	S799	Y795S	795	Missense	distal	-4	no	13.660	13.924	EPSD	COSMIC	8.283	Up-regulation
Atypical_PIKK_DNAPK_PRKDC_ST	Q00839	HNRNPU	P78527	PRKDC	S799	Q800E	800	Missense	proximal	1	no	13.660	5.925	EPSD	COSMIC	8.283	Loss
Atypical_PIKK_DNAPK_PRKDC_ST	P15927	RPA2	P78527	PRKDC	S8	Y14N	14	Missense	distal	6	no	9.806	9.799	EPSD;PhosphoSitePlus	COSMIC	8.283	Down-regulation
Atypical_PIKK_DNAPK_PRKDC_ST	P15927	RPA2	P78527	PRKDC	S13	Y14N	14	Missense	proximal	1	no	9.212	6.579	EPSD	COSMIC	8.283	Loss
Atypical_PIKK_DNAPK_PRKDC_ST	P15927	RPA2	P78527	PRKDC	T21	Y14N	14	Missense	distal	-7	no	13.040	13.151	EPSD;PhosphoSitePlus	COSMIC	8.283	Up-regulation
Atypical_PIKK_DNAPK_PRKDC_ST	P15927	RPA2	P78527	PRKDC	S29	Q34K	34	Missense	distal	5	no	11.749	11.506	PhosphoSitePlus;EPSD	COSMIC	8.283	Down-regulation
Atypical_PIKK_DNAPK_PRKDC_ST	P15927	RPA2	P78527	PRKDC	S33	Q34K	34	Missense	proximal	1	no	11.665	0.460	EPSD;PhosphoSitePlus	COSMIC	8.283	Loss
Atypical_PIKK_DNAPK_PRKDC_ST	P15927	RPA2	P78527	PRKDC	S33	K37N	37	Missense	distal	4	no	11.665	11.674	EPSD;PhosphoSitePlus	COSMIC	8.283	Up-regulation
Atypical_PIKK_DNAPK_PRKDC_ST	P15927	RPA2	P78527	PRKDC	S52	S56F	56	Missense	distal	4	no	9.616	9.591	EPSD	COSMIC	8.283	Down-regulation
Atypical_PIKK_DNAPK_PRKDC_ST	P15927	RPA2	P78527	PRKDC	S52	S52F	52	Missense	central	0	yes	9.616	0.000	EPSD	COSMIC	8.283	Loss
Atypical_PIKK_DNAPK_PRKDC_ST	P15927	RPA2	P78527	PRKDC	S52	L59F	59	Missense	distal	7	no	9.616	9.668	EPSD	COSMIC	8.283	Up-regulation
Atypical_PIKK_DNAPK_PRKDC_ST	P15927	RPA2	P78527	PRKDC	S174	P176S	176	Missense	proximal	2	no	12.776	13.007	EPSD	COSMIC	8.283	Up-regulation
Atypical_PIKK_DNAPK_PRKDC_ST	P24928	POLR2A	P78527	PRKDC	S8	P7F	7	Missense	proximal	-1	no	8.663	8.587	EPSD	COSMIC	8.283	Down-regulation
Atypical_PIKK_DNAPK_PRKDC_ST	P24928	POLR2A	P78527	PRKDC	S8	P7H	7	Missense	proximal	-1	no	8.663	8.635	EPSD	COSMIC	8.283	Down-regulation
Atypical_PIKK_DNAPK_PRKDC_ST	P24928	POLR2A	P78527	PRKDC	S27	G24R	24	Missense	distal	-3	no	11.215	11.120	EPSD	COSMIC	8.283	Down-regulation
Atypical_PIKK_DNAPK_PRKDC_ST	P24928	POLR2A	P78527	PRKDC	S27	R33Q	33	Missense	distal	6	no	11.215	11.251	EPSD	COSMIC;CCLE	8.283	Up-regulation
Atypical_PIKK_DNAPK_PRKDC_ST	P24928	POLR2A	P78527	PRKDC	S27	G24A	24	Missense	distal	-3	no	11.215	11.308	EPSD	COSMIC	8.283	Up-regulation
Atypical_PIKK_DNAPK_PRKDC_ST	Q15648	MED1	P78527	PRKDC	S18	M16I	16	Missense	proximal	-2	no	10.981	11.102	EPSD	COSMIC	8.283	Up-regulation
Atypical_PIKK_DNAPK_PRKDC_ST	Q15648	MED1	P78527	PRKDC	S179	S179F	179	Missense	central	0	yes	8.686	0.000	EPSD	COSMIC	8.283	Loss
Atypical_PIKK_DNAPK_PRKDC_ST	Q15648	MED1	P78527	PRKDC	T212	L211R	211	Missense	proximal	-1	no	9.524	8.743	EPSD	COSMIC	8.283	Down-regulation
Atypical_PIKK_DNAPK_PRKDC_ST	Q15648	MED1	P78527	PRKDC	S621	T623P	623	Missense	proximal	2	no	7.697	8.451	EPSD	COSMIC	8.283	Gain
Atypical_PIKK_DNAPK_PRKDC_ST	Q15648	MED1	P78527	PRKDC	S621	G614E	614	Missense	distal	-7	no	7.697	8.285	EPSD	COSMIC	8.283	Gain
Atypical_PIKK_DNAPK_PRKDC_ST	Q15648	MED1	P78527	PRKDC	T623	T623P	623	Missense	central	0	yes	9.843	0.000	EPSD	COSMIC	8.283	Loss
Atypical_PIKK_DNAPK_PRKDC_ST	Q15648	MED1	P78527	PRKDC	T628	T623P	623	Missense	distal	-5	no	8.665	8.535	EPSD	COSMIC	8.283	Down-regulation
Atypical_PIKK_DNAPK_PRKDC_ST	Q15648	MED1	P78527	PRKDC	S719	P722T	722	Missense	distal	3	no	10.712	10.439	EPSD	COSMIC	8.283	Down-regulation
Atypical_PIKK_DNAPK_PRKDC_ST	Q15648	MED1	P78527	PRKDC	T735	H737Y	737	Missense	proximal	2	no	8.790	8.241	EPSD	COSMIC	8.283	Loss
Atypical_PIKK_DNAPK_PRKDC_ST	Q15648	MED1	P78527	PRKDC	S743	H737Y	737	Missense	distal	-6	no	12.505	12.254	EPSD	COSMIC	8.283	Down-regulation
Atypical_PIKK_DNAPK_PRKDC_ST	Q15648	MED1	P78527	PRKDC	S791	K792Q	792	Missense	proximal	1	no	1.170	12.375	EPSD	COSMIC	8.283	Gain
Atypical_PIKK_DNAPK_PRKDC_ST	Q15648	MED1	P78527	PRKDC	S816	S810C	810	Missense	distal	-6	no	13.784	12.926	EPSD	COSMIC	8.283	Down-regulation
Atypical_PIKK_DNAPK_PRKDC_ST	Q15648	MED1	P78527	PRKDC	S816	H815R	815	Missense	proximal	-1	no	13.784	12.731	EPSD	COSMIC	8.283	Down-regulation
Atypical_PIKK_DNAPK_PRKDC_ST	Q15648	MED1	P78527	PRKDC	S872	P867L	867	Missense	distal	-5	no	12.765	12.777	EPSD	COSMIC	8.283	Up-regulation
Atypical_PIKK_DNAPK_PRKDC_ST	Q15648	MED1	P78527	PRKDC	S874	P867L	867	Missense	distal	-7	no	13.147	13.330	EPSD	COSMIC	8.283	Up-regulation
Atypical_PIKK_DNAPK_PRKDC_ST	Q15648	MED1	P78527	PRKDC	S900	L906F	906	Missense	distal	6	no	11.935	11.940	EPSD	COSMIC	8.283	Up-regulation
Atypical_PIKK_DNAPK_PRKDC_ST	Q15648	MED1	P78527	PRKDC	S953	G955S	955	Missense	proximal	2	no	10.908	11.684	EPSD	COSMIC	8.283	Up-regulation
Atypical_PIKK_DNAPK_PRKDC_ST	Q15648	MED1	P78527	PRKDC	S953	H950Y	950	Missense	distal	-3	no	10.908	11.004	EPSD	COSMIC	8.283	Up-regulation
Atypical_PIKK_DNAPK_PRKDC_ST	Q15648	MED1	P78527	PRKDC	S1000	G993E	993	Missense	distal	-7	no	8.369	8.958	EPSD	COSMIC	8.283	Up-regulation
Atypical_PIKK_DNAPK_PRKDC_ST	Q15648	MED1	P78527	PRKDC	S1000	T998I	998	Missense	proximal	-2	no	8.369	8.555	EPSD	COSMIC	8.283	Up-regulation
Atypical_PIKK_DNAPK_PRKDC_ST	Q15648	MED1	P78527	PRKDC	S1000	S1000F	1000	Missense	central	0	yes	8.369	0.000	EPSD	COSMIC	8.283	Loss
Atypical_PIKK_DNAPK_PRKDC_ST	Q15648	MED1	P78527	PRKDC	S1021	P1022Q	1022	Missense	proximal	1	no	7.531	12.012	EPSD	COSMIC	8.283	Gain
Atypical_PIKK_DNAPK_PRKDC_ST	Q15648	MED1	P78527	PRKDC	S1042	G1044C	1044	Missense	proximal	2	no	8.436	8.062	EPSD	COSMIC	8.283	Loss
Atypical_PIKK_DNAPK_PRKDC_ST	Q15648	MED1	P78527	PRKDC	S1042	S1042L	1042	Missense	central	0	yes	8.436	0.000	EPSD	COSMIC	8.283	Loss
Atypical_PIKK_DNAPK_PRKDC_ST	Q15648	MED1	P78527	PRKDC	S1049	G1044C	1044	Missense	distal	-5	no	11.137	10.981	EPSD	COSMIC	8.283	Down-regulation
Atypical_PIKK_DNAPK_PRKDC_ST	Q15648	MED1	P78527	PRKDC	S1049	P1052F	1052	Missense	distal	3	no	11.137	10.898	EPSD	COSMIC	8.283	Down-regulation
Atypical_PIKK_DNAPK_PRKDC_ST	Q15648	MED1	P78527	PRKDC	S1049	P1052S	1052	Missense	distal	3	no	11.137	11.184	EPSD	COSMIC	8.283	Up-regulation
Atypical_PIKK_DNAPK_PRKDC_ST	Q15648	MED1	P78527	PRKDC	S1049	S1042L	1042	Missense	distal	-7	no	11.137	10.670	EPSD	COSMIC	8.283	Down-regulation
Atypical_PIKK_DNAPK_PRKDC_ST	Q15648	MED1	P78527	PRKDC	T1051	G1044C	1044	Missense	distal	-7	no	8.611	7.994	EPSD	COSMIC	8.283	Loss
Atypical_PIKK_DNAPK_PRKDC_ST	Q15648	MED1	P78527	PRKDC	T1051	P1052F	1052	Missense	proximal	1	no	8.611	6.234	EPSD	COSMIC	8.283	Loss
Atypical_PIKK_DNAPK_PRKDC_ST	Q15648	MED1	P78527	PRKDC	T1051	P1052S	1052	Missense	proximal	1	no	8.611	4.256	EPSD	COSMIC	8.283	Loss
Atypical_PIKK_DNAPK_PRKDC_ST	Q15648	MED1	P78527	PRKDC	S1092	K1095E	1095	Missense	distal	3	no	7.858	8.416	EPSD	COSMIC;GDSC;CCLE	8.283	Gain
Atypical_PIKK_DNAPK_PRKDC_ST	Q15648	MED1	P78527	PRKDC	S1134	S1137F	1137	Missense	distal	3	no	13.157	12.871	EPSD	COSMIC	8.283	Down-regulation
Atypical_PIKK_DNAPK_PRKDC_ST	Q15648	MED1	P78527	PRKDC	S1138	S1137F	1137	Missense	proximal	-1	no	8.125	8.389	EPSD	COSMIC	8.283	Gain
Atypical_PIKK_DNAPK_PRKDC_ST	Q15648	MED1	P78527	PRKDC	S1141	S1137F	1137	Missense	distal	-4	no	16.658	16.142	EPSD	COSMIC	8.283	Down-regulation
Atypical_PIKK_DNAPK_PRKDC_ST	Q15648	MED1	P78527	PRKDC	S1185	P1178L	1178	Missense	distal	-7	no	8.517	8.700	EPSD	COSMIC	8.283	Up-regulation
Atypical_PIKK_DNAPK_PRKDC_ST	Q15648	MED1	P78527	PRKDC	S1254	P1260S	1260	Missense	distal	6	no	9.536	9.527	EPSD	COSMIC	8.283	Down-regulation
Atypical_PIKK_DNAPK_PRKDC_ST	Q15648	MED1	P78527	PRKDC	S1256	P1260S	1260	Missense	distal	4	no	12.287	12.313	EPSD	COSMIC	8.283	Up-regulation
Atypical_PIKK_DNAPK_PRKDC_ST	Q15648	MED1	P78527	PRKDC	T1267	P1260S	1260	Missense	distal	-7	no	7.801	8.451	EPSD	COSMIC	8.283	Gain
Atypical_PIKK_DNAPK_PRKDC_ST	Q15648	MED1	P78527	PRKDC	S1282	S1283F	1283	Missense	proximal	1	no	6.489	8.466	EPSD	COSMIC	8.283	Gain
Atypical_PIKK_DNAPK_PRKDC_ST	Q15648	MED1	P78527	PRKDC	S1283	S1283F	1283	Missense	central	0	yes	12.970	0.000	EPSD	COSMIC	8.283	Loss
Atypical_PIKK_DNAPK_PRKDC_ST	Q15648	MED1	P78527	PRKDC	S1283	S1290Y	1290	Missense	distal	7	no	12.970	12.514	EPSD	COSMIC	8.283	Down-regulation
Atypical_PIKK_DNAPK_PRKDC_ST	Q15648	MED1	P78527	PRKDC	S1283	S1278A	1278	Missense	distal	-5	no	12.970	12.834	EPSD	COSMIC	8.283	Down-regulation
Atypical_PIKK_DNAPK_PRKDC_ST	Q15648	MED1	P78527	PRKDC	S1289	S1290Y	1290	Missense	proximal	1	no	3.730	8.571	EPSD	COSMIC	8.283	Gain
Atypical_PIKK_DNAPK_PRKDC_ST	Q15648	MED1	P78527	PRKDC	S1371	S1374P	1374	Missense	distal	3	no	8.518	8.472	EPSD	COSMIC	8.283	Down-regulation
Atypical_PIKK_DNAPK_PRKDC_ST	Q15648	MED1	P78527	PRKDC	S1371	S1374F	1374	Missense	distal	3	no	8.518	8.232	EPSD	COSMIC	8.283	Loss
Atypical_PIKK_DNAPK_PRKDC_ST	Q15648	MED1	P78527	PRKDC	S1371	T1367A	1367	Missense	distal	-4	no	8.518	9.090	EPSD	COSMIC	8.283	Up-regulation
Atypical_PIKK_DNAPK_PRKDC_ST	Q15648	MED1	P78527	PRKDC	S1447	R1445C	1445	Missense	proximal	-2	no	9.087	9.116	EPSD	COSMIC	8.283	Up-regulation
Atypical_PIKK_DNAPK_PRKDC_ST	Q15648	MED1	P78527	PRKDC	T1457	P1458S	1458	Missense	proximal	1	no	10.753	6.398	PhosphoSitePlus	COSMIC	8.283	Loss
Atypical_PIKK_DNAPK_PRKDC_ST	Q15648	MED1	P78527	PRKDC	S1561	P1562S	1562	Missense	proximal	1	no	11.063	6.708	EPSD	COSMIC	8.283	Loss
Atypical_PIKK_DNAPK_PRKDC_ST	P07954	FH	P78527	PRKDC	S46	R51W	51	Missense	distal	5	no	12.660	12.573	EPSD	COSMIC	8.283	Down-regulation
Atypical_PIKK_DNAPK_PRKDC_ST	P07954	FH	P78527	PRKDC	S46	R43Q	43	Missense	distal	-3	no	12.660	13.185	EPSD	COSMIC	8.283	Up-regulation
Atypical_PIKK_DNAPK_PRKDC_ST	P07954	FH	P78527	PRKDC	T236	L242R	242	Missense	distal	6	no	10.566	10.548	PhosphoSitePlus	COSMIC	8.283	Down-regulation
Atypical_PIKK_DNAPK_PRKDC_ST	P07954	FH	P78527	PRKDC	T236	Q237R	237	Missense	proximal	1	no	10.566	0.152	PhosphoSitePlus	COSMIC	8.283	Loss
Atypical_PIKK_DNAPK_PRKDC_ST	P07954	FH	P78527	PRKDC	T236	H235Y	235	Missense	proximal	-1	no	10.566	10.593	PhosphoSitePlus	COSMIC	8.283	Up-regulation
Atypical_PIKK_DNAPK_PRKDC_ST	O43918	AIRE	P78527	PRKDC	T68	A73T	73	Missense	distal	5	no	14.219	14.053	PhosphoSitePlus;EPSD	COSMIC	8.283	Down-regulation
Atypical_PIKK_DNAPK_PRKDC_ST	O43918	AIRE	P78527	PRKDC	S107	R113G	113	Missense	distal	6	no	12.995	13.005	EPSD	COSMIC	8.283	Up-regulation
Atypical_PIKK_DNAPK_PRKDC_ST	O43918	AIRE	P78527	PRKDC	S107	P109T	109	Missense	proximal	2	no	12.995	12.241	EPSD	COSMIC	8.283	Down-regulation
Atypical_PIKK_DNAPK_PRKDC_ST	O43918	AIRE	P78527	PRKDC	S107	K111E	111	Missense	distal	4	no	12.995	13.007	EPSD	COSMIC	8.283	Up-regulation
Atypical_PIKK_DNAPK_PRKDC_ST	O43918	AIRE	P78527	PRKDC	S156	T151N	151	Missense	distal	-5	no	10.677	10.763	EPSD;PhosphoSitePlus	COSMIC	8.283	Up-regulation
Atypical_PIKK_DNAPK_PRKDC_ST	O43918	AIRE	P78527	PRKDC	T232	G227D	227	Missense	distal	-5	no	9.296	9.433	EPSD	COSMIC;GDSC;CCLE	8.283	Up-regulation
Atypical_PIKK_DNAPK_PRKDC_ST	O43918	AIRE	P78527	PRKDC	S491	L495M	495	Missense	distal	4	no	8.649	8.639	EPSD	COSMIC	8.283	Down-regulation
Atypical_PIKK_DNAPK_PRKDC_ST	O43918	AIRE	P78527	PRKDC	S491	E485D	485	Missense	distal	-6	no	8.649	8.498	EPSD	COSMIC	8.283	Down-regulation
Atypical_PIKK_DNAPK_PRKDC_ST	P11831	SRF	P78527	PRKDC	T4	A9T	9	Missense	distal	5	no	12.769	12.604	EPSD	COSMIC	8.283	Down-regulation
Atypical_PIKK_DNAPK_PRKDC_ST	P11831	SRF	P78527	PRKDC	S16	A9T	9	Missense	distal	-7	no	8.328	8.060	EPSD	COSMIC	8.283	Loss
Atypical_PIKK_DNAPK_PRKDC_ST	P11831	SRF	P78527	PRKDC	S101	E94K	94	Missense	distal	-7	no	8.545	8.291	EPSD	COSMIC	8.283	Down-regulation
Atypical_PIKK_DNAPK_PRKDC_ST	P11831	SRF	P78527	PRKDC	S224	P226L	226	Missense	proximal	2	no	9.633	8.675	EPSD	COSMIC	8.283	Down-regulation
Atypical_PIKK_DNAPK_PRKDC_ST	P11831	SRF	P78527	PRKDC	S224	R227G	227	Missense	distal	3	no	9.633	9.846	EPSD	COSMIC	8.283	Up-regulation
Atypical_PIKK_DNAPK_PRKDC_ST	P11831	SRF	P78527	PRKDC	S224	L219I	219	Missense	distal	-5	no	9.633	9.052	EPSD	COSMIC	8.283	Down-regulation
Atypical_PIKK_DNAPK_PRKDC_ST	P11831	SRF	P78527	PRKDC	S435	V430M	430	Missense	distal	-5	no	13.175	13.334	EPSD;PhosphoSitePlus	COSMIC	8.283	Up-regulation
Atypical_PIKK_DNAPK_PRKDC_ST	P11831	SRF	P78527	PRKDC	S435	T429I	429	Missense	distal	-6	no	13.175	12.296	EPSD;PhosphoSitePlus	COSMIC	8.283	Down-regulation
Atypical_PIKK_DNAPK_PRKDC_ST	P11831	SRF	P78527	PRKDC	S435	A433T	433	Missense	proximal	-2	no	13.175	13.256	EPSD;PhosphoSitePlus	COSMIC	8.283	Up-regulation
Atypical_PIKK_DNAPK_PRKDC_ST	P11831	SRF	P78527	PRKDC	S435	A433V	433	Missense	proximal	-2	no	13.175	13.297	EPSD;PhosphoSitePlus	COSMIC	8.283	Up-regulation
Atypical_PIKK_DNAPK_PRKDC_ST	P11831	SRF	P78527	PRKDC	S435	A437S	437	Missense	proximal	2	no	13.175	13.202	EPSD;PhosphoSitePlus	COSMIC	8.283	Up-regulation
Atypical_PIKK_DNAPK_PRKDC_ST	P11831	SRF	P78527	PRKDC	S446	Q449H	449	Missense	distal	3	no	13.011	12.702	PhosphoSitePlus;EPSD	COSMIC	8.283	Down-regulation
Atypical_PIKK_DNAPK_PRKDC_ST	P31749	AKT1	P78527	PRKDC	S124	G123D	123	Missense	proximal	-1	no	10.030	11.044	EPSD	COSMIC	8.283	Up-regulation
Atypical_PIKK_DNAPK_PRKDC_ST	P31749	AKT1	P78527	PRKDC	S124	D127N	127	Missense	distal	3	no	10.030	10.036	EPSD	COSMIC	8.283	Up-regulation
Atypical_PIKK_DNAPK_PRKDC_ST	P31749	AKT1	P78527	PRKDC	S124	G130R	130	Missense	distal	6	no	10.030	10.020	EPSD	COSMIC	8.283	Down-regulation
Atypical_PIKK_DNAPK_PRKDC_ST	P31749	AKT1	P78527	PRKDC	T211	N204K	204	Missense	distal	-7	no	8.453	8.560	EPSD	COSMIC	8.283	Up-regulation
Atypical_PIKK_DNAPK_PRKDC_ST	P31749	AKT1	P78527	PRKDC	T211	R206K	206	Missense	distal	-5	no	8.453	8.893	EPSD	COSMIC	8.283	Up-regulation
Atypical_PIKK_DNAPK_PRKDC_ST	P31749	AKT1	P78527	PRKDC	T211	F217L	217	Missense	distal	6	no	8.453	8.449	EPSD	COSMIC	8.283	Down-regulation
Atypical_PIKK_DNAPK_PRKDC_ST	P31749	AKT1	P78527	PRKDC	T312	M306T	306	Missense	distal	-6	no	9.481	9.614	EPSD	COSMIC	8.283	Up-regulation
Atypical_PIKK_DNAPK_PRKDC_ST	P31749	AKT1	P78527	PRKDC	T312	M306L	306	Missense	distal	-6	no	9.481	9.717	EPSD	COSMIC	8.283	Up-regulation
Atypical_PIKK_DNAPK_PRKDC_ST	P31749	AKT1	P78527	PRKDC	T312	M306I	306	Missense	distal	-6	no	9.481	8.735	EPSD	COSMIC	8.283	Down-regulation
Atypical_PIKK_DNAPK_PRKDC_ST	P31749	AKT1	P78527	PRKDC	T312	T312I	312	Missense	central	0	yes	9.481	0.000	EPSD	COSMIC	8.283	Loss
Atypical_PIKK_DNAPK_PRKDC_ST	P31749	AKT1	P78527	PRKDC	S422	V416M	416	Missense	distal	-6	no	8.605	8.837	EPSD	COSMIC	8.283	Up-regulation
Atypical_PIKK_DNAPK_PRKDC_ST	P31749	AKT1	P78527	PRKDC	S422	S422R	422	Missense	central	0	yes	8.605	0.000	EPSD	COSMIC	8.283	Loss
Atypical_PIKK_DNAPK_PRKDC_ST	P31749	AKT1	P78527	PRKDC	S473	S477N	477	Missense	distal	4	no	9.351	9.371	PhosphoSitePlus	COSMIC	8.283	Up-regulation
Atypical_PIKK_DNAPK_PRKDC_ST	P31749	AKT1	P78527	PRKDC	S473	P470L	470	Missense	distal	-3	no	9.351	9.151	PhosphoSitePlus	COSMIC	8.283	Down-regulation
Atypical_PIKK_DNAPK_PRKDC_ST	Q9H4A6	GOLPH3	P78527	PRKDC	T143	T148M	148	Missense	distal	5	no	14.782	14.700	EPSD;PhosphoSitePlus	COSMIC	8.283	Down-regulation
Atypical_PIKK_DNAPK_PRKDC_ST	O96017	CHEK2	P78527	PRKDC	S12	H13Y	13	Missense	proximal	1	no	5.228	11.568	EPSD	COSMIC	8.283	Gain
Atypical_PIKK_DNAPK_PRKDC_ST	O96017	CHEK2	P78527	PRKDC	S12	H13N	13	Missense	proximal	1	no	5.228	8.935	EPSD	COSMIC	8.283	Gain
Atypical_PIKK_DNAPK_PRKDC_ST	O96017	CHEK2	P78527	PRKDC	S19	H13Y	13	Missense	distal	-6	no	13.226	12.975	EPSD	COSMIC	8.283	Down-regulation
Atypical_PIKK_DNAPK_PRKDC_ST	O96017	CHEK2	P78527	PRKDC	S19	V25I	25	Missense	distal	6	no	13.226	13.204	EPSD	COSMIC	8.283	Down-regulation
Atypical_PIKK_DNAPK_PRKDC_ST	O96017	CHEK2	P78527	PRKDC	S19	H13N	13	Missense	distal	-6	no	13.226	13.315	EPSD	COSMIC	8.283	Up-regulation
Atypical_PIKK_DNAPK_PRKDC_ST	O96017	CHEK2	P78527	PRKDC	S19	S19L	19	Missense	central	0	yes	13.226	0.000	EPSD	COSMIC	8.283	Loss
Atypical_PIKK_DNAPK_PRKDC_ST	O96017	CHEK2	P78527	PRKDC	S24	V25I	25	Missense	proximal	1	no	8.931	2.016	EPSD	COSMIC	8.283	Loss
Atypical_PIKK_DNAPK_PRKDC_ST	O96017	CHEK2	P78527	PRKDC	S24	S19L	19	Missense	distal	-5	no	8.931	8.573	EPSD	COSMIC	8.283	Down-regulation
Atypical_PIKK_DNAPK_PRKDC_ST	O96017	CHEK2	P78527	PRKDC	T26	V25I	25	Missense	proximal	-1	no	13.876	13.411	EPSD	COSMIC	8.283	Down-regulation
Atypical_PIKK_DNAPK_PRKDC_ST	O96017	CHEK2	P78527	PRKDC	T26	S19L	19	Missense	distal	-7	no	13.876	13.409	EPSD	COSMIC	8.283	Down-regulation
Atypical_PIKK_DNAPK_PRKDC_ST	O96017	CHEK2	P78527	PRKDC	S28	V25I	25	Missense	distal	-3	no	12.733	12.472	EPSD	COSMIC	8.283	Down-regulation
Atypical_PIKK_DNAPK_PRKDC_ST	O96017	CHEK2	P78527	PRKDC	S50	M46T	46	Missense	distal	-4	no	15.189	15.267	EPSD	COSMIC	8.283	Up-regulation
Atypical_PIKK_DNAPK_PRKDC_ST	O96017	CHEK2	P78527	PRKDC	S50	S52P	52	Missense	proximal	2	no	15.189	14.959	EPSD	COSMIC;GDSC;CCLE	8.283	Down-regulation
Atypical_PIKK_DNAPK_PRKDC_ST	O96017	CHEK2	P78527	PRKDC	S50	S49C	49	Missense	proximal	-1	no	15.189	14.508	EPSD	COSMIC	8.283	Down-regulation
Atypical_PIKK_DNAPK_PRKDC_ST	O96017	CHEK2	P78527	PRKDC	S50	S50N	50	Missense	central	0	yes	15.189	0.000	EPSD	COSMIC	8.283	Loss
Atypical_PIKK_DNAPK_PRKDC_ST	O96017	CHEK2	P78527	PRKDC	S62	Q69R	69	Missense	distal	7	no	9.154	7.883	EPSD	COSMIC	8.283	Loss
Atypical_PIKK_DNAPK_PRKDC_ST	O96017	CHEK2	P78527	PRKDC	T68	Q69R	69	Missense	proximal	1	no	13.763	3.349	PhosphoSitePlus;EPSD	COSMIC	8.283	Loss
Atypical_PIKK_DNAPK_PRKDC_ST	O96017	CHEK2	P78527	PRKDC	S260	K253E	253	Missense	distal	-7	no	8.348	8.603	EPSD	COSMIC	8.283	Up-regulation
Atypical_PIKK_DNAPK_PRKDC_ST	O96017	CHEK2	P78527	PRKDC	S260	K255R	255	Missense	distal	-5	no	8.348	7.909	EPSD	COSMIC	8.283	Loss
Atypical_PIKK_DNAPK_PRKDC_ST	O96017	CHEK2	P78527	PRKDC	S357	D361Y	361	Missense	distal	4	no	11.047	11.058	EPSD	COSMIC	8.283	Up-regulation
Atypical_PIKK_DNAPK_PRKDC_ST	O96017	CHEK2	P78527	PRKDC	S357	E360Q	360	Missense	distal	3	no	11.047	10.948	EPSD	COSMIC	8.283	Down-regulation
Atypical_PIKK_DNAPK_PRKDC_ST	O96017	CHEK2	P78527	PRKDC	S357	D361E	361	Missense	distal	4	no	11.047	11.073	EPSD	COSMIC	8.283	Up-regulation
Atypical_PIKK_DNAPK_PRKDC_ST	O96017	CHEK2	P78527	PRKDC	S357	S356L	356	Missense	proximal	-1	no	11.047	11.085	EPSD	COSMIC	8.283	Up-regulation
Atypical_PIKK_DNAPK_PRKDC_ST	O96017	CHEK2	P78527	PRKDC	S357	L355P	355	Missense	proximal	-2	no	11.047	11.049	EPSD	COSMIC;CCLE	8.283	Up-regulation
Atypical_PIKK_DNAPK_PRKDC_ST	O96017	CHEK2	P78527	PRKDC	T383	Y390C	390	Missense	distal	7	no	8.602	7.597	EPSD;PhosphoSitePlus	COSMIC	8.283	Loss
Atypical_PIKK_DNAPK_PRKDC_ST	O96017	CHEK2	P78527	PRKDC	T383	M381I	381	Missense	proximal	-2	no	8.602	8.723	EPSD;PhosphoSitePlus	COSMIC	8.283	Up-regulation
Atypical_PIKK_DNAPK_PRKDC_ST	O96017	CHEK2	P78527	PRKDC	T383	M381V	381	Missense	proximal	-2	no	8.602	8.578	EPSD;PhosphoSitePlus	COSMIC	8.283	Down-regulation
Atypical_PIKK_DNAPK_PRKDC_ST	O96017	CHEK2	P78527	PRKDC	T383	S379C	379	Missense	distal	-4	no	8.602	7.841	EPSD;PhosphoSitePlus	COSMIC	8.283	Loss
Atypical_PIKK_DNAPK_PRKDC_ST	O96017	CHEK2	P78527	PRKDC	T383	Y390D	390	Missense	distal	7	no	8.602	9.166	EPSD;PhosphoSitePlus	COSMIC	8.283	Up-regulation
Atypical_PIKK_DNAPK_PRKDC_ST	O96017	CHEK2	P78527	PRKDC	T387	Y390C	390	Missense	distal	3	no	9.198	8.991	EPSD;PhosphoSitePlus	COSMIC	8.283	Down-regulation
Atypical_PIKK_DNAPK_PRKDC_ST	O96017	CHEK2	P78527	PRKDC	T387	M381I	381	Missense	distal	-6	no	9.198	8.452	EPSD;PhosphoSitePlus	COSMIC	8.283	Down-regulation
Atypical_PIKK_DNAPK_PRKDC_ST	O96017	CHEK2	P78527	PRKDC	T387	M381V	381	Missense	distal	-6	no	9.198	8.966	EPSD;PhosphoSitePlus	COSMIC	8.283	Down-regulation
Atypical_PIKK_DNAPK_PRKDC_ST	O96017	CHEK2	P78527	PRKDC	T387	E394K	394	Missense	distal	7	no	9.198	8.385	EPSD;PhosphoSitePlus	COSMIC;CCLE	8.283	Down-regulation
Atypical_PIKK_DNAPK_PRKDC_ST	O96017	CHEK2	P78527	PRKDC	T387	A392S	392	Missense	distal	5	no	9.198	9.177	EPSD;PhosphoSitePlus	COSMIC	8.283	Down-regulation
Atypical_PIKK_DNAPK_PRKDC_ST	O96017	CHEK2	P78527	PRKDC	T387	P393L	393	Missense	distal	6	no	9.198	9.187	EPSD;PhosphoSitePlus	COSMIC	8.283	Down-regulation
Atypical_PIKK_DNAPK_PRKDC_ST	O96017	CHEK2	P78527	PRKDC	T387	Y390D	390	Missense	distal	3	no	9.198	9.388	EPSD;PhosphoSitePlus	COSMIC	8.283	Up-regulation
Atypical_PIKK_DNAPK_PRKDC_ST	O96017	CHEK2	P78527	PRKDC	T432	P426L	426	Missense	distal	-6	no	9.582	9.701	EPSD	COSMIC	8.283	Up-regulation
Atypical_PIKK_DNAPK_PRKDC_ST	O96017	CHEK2	P78527	PRKDC	T432	K437Q	437	Missense	distal	5	no	9.582	9.825	EPSD	COSMIC	8.283	Up-regulation
Atypical_PIKK_DNAPK_PRKDC_ST	O96017	CHEK2	P78527	PRKDC	S518	R519Q	519	Missense	proximal	1	no	-0.163	10.252	EPSD	COSMIC	8.283	Gain
Atypical_PIKK_DNAPK_PRKDC_ST	P42575	CASP2	P78527	PRKDC	S139	P141S	141	Missense	proximal	2	no	9.692	9.923	PhosphoSitePlus	COSMIC	8.283	Up-regulation
Atypical_PIKK_DNAPK_PRKDC_ST	P42575	CASP2	P78527	PRKDC	S139	D137N	137	Missense	proximal	-2	no	9.692	9.715	PhosphoSitePlus	COSMIC	8.283	Up-regulation
Atypical_PIKK_DNAPK_PRKDC_ST	P42575	CASP2	P78527	PRKDC	S139	P143S	143	Missense	distal	4	no	9.692	9.718	PhosphoSitePlus	COSMIC	8.283	Up-regulation
Atypical_PIKK_DNAPK_PRKDC_ST	P42575	CASP2	P78527	PRKDC	S164	N167Y	167	Missense	distal	3	no	11.019	10.823	EPSD	COSMIC	8.283	Down-regulation
Atypical_PIKK_DNAPK_PRKDC_ST	Q9BQ15	NABP2	P78527	PRKDC	T117	P113S	113	Missense	distal	-4	no	13.888	14.288	EPSD	COSMIC	8.283	Up-regulation
Atypical_PIKK_DNAPK_PRKDC_ST	Q9BQ15	NABP2	P78527	PRKDC	T117	A120T	120	Missense	distal	3	no	13.888	13.633	EPSD	COSMIC	8.283	Down-regulation
Atypical_PIKK_DNAPK_PRKDC_ST	Q9BQ15	NABP2	P78527	PRKDC	S134	P131S	131	Missense	distal	-3	no	14.123	13.985	PhosphoSitePlus	COSMIC	8.283	Down-regulation
Atypical_PIKK_DNAPK_PRKDC_ST	Q9BQ15	NABP2	P78527	PRKDC	S134	D128E	128	Missense	distal	-6	no	14.123	14.274	PhosphoSitePlus	COSMIC	8.283	Up-regulation
Atypical_PIKK_DNAPK_PRKDC_ST	Q9BQ15	NABP2	P78527	PRKDC	S182	P175H	175	Missense	distal	-7	no	11.238	12.039	EPSD	COSMIC	8.283	Up-regulation
Atypical_PIKK_DNAPK_PRKDC_ST	P49917	LIG4	P78527	PRKDC	S170	K169N	169	Missense	proximal	-1	no	7.928	8.528	EPSD	COSMIC	8.283	Gain
Atypical_PIKK_DNAPK_PRKDC_ST	P49917	LIG4	P78527	PRKDC	T788	N783D	783	Missense	distal	-5	no	9.154	9.144	EPSD	COSMIC	8.283	Down-regulation
Atypical_PIKK_DNAPK_PRKDC_ST	P49917	LIG4	P78527	PRKDC	T788	S794Y	794	Missense	distal	6	no	9.154	9.166	EPSD	COSMIC	8.283	Up-regulation
Atypical_PIKK_DNAPK_PRKDC_ST	P49917	LIG4	P78527	PRKDC	T788	E791K	791	Missense	distal	3	no	9.154	8.596	EPSD	COSMIC	8.283	Down-regulation
Atypical_PIKK_DNAPK_PRKDC_ST	P08670	VIM	P78527	PRKDC	S10	R4K	4	Missense	distal	-6	no	9.148	9.482	EPSD	COSMIC	8.283	Up-regulation
Atypical_PIKK_DNAPK_PRKDC_ST	P08670	VIM	P78527	PRKDC	T37	R36H	36	Missense	proximal	-1	no	8.227	9.280	EPSD	COSMIC	8.283	Gain
Atypical_PIKK_DNAPK_PRKDC_ST	P08670	VIM	P78527	PRKDC	T37	S34P	34	Missense	distal	-3	no	8.227	8.365	EPSD	COSMIC	8.283	Gain
Atypical_PIKK_DNAPK_PRKDC_ST	P08670	VIM	P78527	PRKDC	S55	S56Y	56	Missense	proximal	1	no	4.899	9.740	EPSD	COSMIC	8.283	Gain
Atypical_PIKK_DNAPK_PRKDC_ST	P08670	VIM	P78527	PRKDC	S56	G59N	59	Missense	distal	3	no	9.041	9.343	EPSD;PhosphoSitePlus	COSMIC	8.283	Up-regulation
Atypical_PIKK_DNAPK_PRKDC_ST	P08670	VIM	P78527	PRKDC	S56	S55A	55	Missense	proximal	-1	no	9.041	9.450	EPSD;PhosphoSitePlus	COSMIC	8.283	Up-regulation
Atypical_PIKK_DNAPK_PRKDC_ST	P08670	VIM	P78527	PRKDC	S56	G59V	59	Missense	distal	3	no	9.041	8.713	EPSD;PhosphoSitePlus	COSMIC	8.283	Down-regulation
Atypical_PIKK_DNAPK_PRKDC_ST	P08670	VIM	P78527	PRKDC	S56	S51N	51	Missense	distal	-5	no	9.041	8.886	EPSD;PhosphoSitePlus	COSMIC	8.283	Down-regulation
Atypical_PIKK_DNAPK_PRKDC_ST	P08670	VIM	P78527	PRKDC	S56	S56Y	56	Missense	central	0	yes	9.041	0.000	EPSD;PhosphoSitePlus	COSMIC	8.283	Loss
Atypical_PIKK_DNAPK_PRKDC_ST	P08670	VIM	P78527	PRKDC	S214	N212S	212	Missense	proximal	-2	no	10.423	10.445	EPSD	COSMIC	8.283	Up-regulation
Atypical_PIKK_DNAPK_PRKDC_ST	P08670	VIM	P78527	PRKDC	S278	V279M	279	Missense	proximal	1	no	8.729	2.956	EPSD	COSMIC;GDSC;CCLE	8.283	Loss
Atypical_PIKK_DNAPK_PRKDC_ST	P08670	VIM	P78527	PRKDC	S278	N283S	283	Missense	distal	5	no	8.729	8.804	EPSD	COSMIC	8.283	Up-regulation
Atypical_PIKK_DNAPK_PRKDC_ST	P08670	VIM	P78527	PRKDC	S278	D271V	271	Missense	distal	-7	no	8.729	7.921	EPSD	COSMIC	8.283	Loss
Atypical_PIKK_DNAPK_PRKDC_ST	P08670	VIM	P78527	PRKDC	S430	V434G	434	Missense	distal	4	no	11.345	11.387	EPSD;PhosphoSitePlus	COSMIC	8.283	Up-regulation
Atypical_PIKK_DNAPK_PRKDC_ST	P08670	VIM	P78527	PRKDC	S430	E425K	425	Missense	distal	-5	no	11.345	11.293	EPSD;PhosphoSitePlus	COSMIC	8.283	Down-regulation
Atypical_PIKK_DNAPK_PRKDC_ST	P08670	VIM	P78527	PRKDC	S430	L433M	433	Missense	distal	3	no	11.345	11.196	EPSD;PhosphoSitePlus	COSMIC	8.283	Down-regulation
Atypical_PIKK_DNAPK_PRKDC_ST	P08670	VIM	P78527	PRKDC	S459	Q453E	453	Missense	distal	-6	no	12.148	12.083	PhosphoSitePlus;EPSD	COSMIC;GDSC;CCLE	8.283	Down-regulation
Atypical_PIKK_DNAPK_PRKDC_ST	P08670	VIM	P78527	PRKDC	S459	I455V	455	Missense	distal	-4	no	12.148	12.586	PhosphoSitePlus;EPSD	COSMIC	8.283	Up-regulation
Atypical_PIKK_DNAPK_PRKDC_ST	P18887	XRCC1	P78527	PRKDC	S151	F149V	149	Missense	proximal	-2	no	9.442	9.508	EPSD	COSMIC	8.283	Up-regulation
Atypical_PIKK_DNAPK_PRKDC_ST	P18887	XRCC1	P78527	PRKDC	S162	Q163R	163	Missense	proximal	1	no	13.152	2.737	EPSD	COSMIC	8.283	Loss
Atypical_PIKK_DNAPK_PRKDC_ST	P18887	XRCC1	P78527	PRKDC	S210	A214V	214	Missense	distal	4	no	11.850	11.782	EPSD	COSMIC	8.283	Down-regulation
Atypical_PIKK_DNAPK_PRKDC_ST	P18887	XRCC1	P78527	PRKDC	T215	A214V	214	Missense	proximal	-1	no	9.262	7.951	EPSD	COSMIC	8.283	Loss
Atypical_PIKK_DNAPK_PRKDC_ST	P18887	XRCC1	P78527	PRKDC	S220	A214V	214	Missense	distal	-6	no	9.152	8.397	EPSD	COSMIC	8.283	Down-regulation
Atypical_PIKK_DNAPK_PRKDC_ST	P18887	XRCC1	P78527	PRKDC	S241	R246T	246	Missense	distal	5	no	8.463	8.524	EPSD	COSMIC	8.283	Up-regulation
Atypical_PIKK_DNAPK_PRKDC_ST	P18887	XRCC1	P78527	PRKDC	T281	P282Q	282	Missense	proximal	1	no	8.237	12.718	EPSD	COSMIC	8.283	Gain
Atypical_PIKK_DNAPK_PRKDC_ST	P18887	XRCC1	P78527	PRKDC	T358	H359Q	359	Missense	proximal	1	no	-0.002	10.333	EPSD	COSMIC	8.283	Gain
Atypical_PIKK_DNAPK_PRKDC_ST	P18887	XRCC1	P78527	PRKDC	S371	L374P	374	Missense	distal	3	no	11.590	11.925	PhosphoSitePlus	COSMIC	8.283	Up-regulation
Atypical_PIKK_DNAPK_PRKDC_ST	P18887	XRCC1	P78527	PRKDC	S371	A365T	365	Missense	distal	-6	no	11.590	11.199	PhosphoSitePlus	COSMIC	8.283	Down-regulation
Atypical_PIKK_DNAPK_PRKDC_ST	P18887	XRCC1	P78527	PRKDC	S371	S371N	371	Missense	central	0	yes	11.590	0.000	PhosphoSitePlus	COSMIC	8.283	Loss
Atypical_PIKK_DNAPK_PRKDC_ST	P18887	XRCC1	P78527	PRKDC	S371	P368L	368	Missense	distal	-3	no	11.590	11.389	PhosphoSitePlus	COSMIC	8.283	Down-regulation
Atypical_PIKK_DNAPK_PRKDC_ST	P18887	XRCC1	P78527	PRKDC	S421	G422V	422	Missense	proximal	1	no	7.876	8.585	EPSD	COSMIC	8.283	Gain
Atypical_PIKK_DNAPK_PRKDC_ST	P18887	XRCC1	P78527	PRKDC	S447	P454H	454	Missense	distal	7	no	9.769	9.920	EPSD	COSMIC	8.283	Up-regulation
Atypical_PIKK_DNAPK_PRKDC_ST	P18887	XRCC1	P78527	PRKDC	S447	P454F	454	Missense	distal	7	no	9.769	9.193	EPSD	COSMIC	8.283	Down-regulation
Atypical_PIKK_DNAPK_PRKDC_ST	P18887	XRCC1	P78527	PRKDC	S447	P451S	451	Missense	distal	4	no	9.769	9.795	EPSD	COSMIC	8.283	Up-regulation
Atypical_PIKK_DNAPK_PRKDC_ST	P18887	XRCC1	P78527	PRKDC	T453	P454H	454	Missense	proximal	1	no	11.500	5.646	EPSD	COSMIC	8.283	Loss
Atypical_PIKK_DNAPK_PRKDC_ST	P18887	XRCC1	P78527	PRKDC	T453	P454F	454	Missense	proximal	1	no	11.500	9.123	EPSD	COSMIC	8.283	Down-regulation
Atypical_PIKK_DNAPK_PRKDC_ST	P18887	XRCC1	P78527	PRKDC	T453	P451S	451	Missense	proximal	-2	no	11.500	11.476	EPSD	COSMIC	8.283	Down-regulation
Atypical_PIKK_DNAPK_PRKDC_ST	P18887	XRCC1	P78527	PRKDC	T519	D513H	513	Missense	distal	-6	no	8.365	8.333	EPSD	COSMIC	8.283	Down-regulation
Atypical_PIKK_DNAPK_PRKDC_ST	Q9NUW8	TDP1	P78527	PRKDC	S2	Q3H	3	Missense	proximal	1	no	11.882	1.546	EPSD	COSMIC	8.283	Loss
Atypical_PIKK_DNAPK_PRKDC_ST	Q9NUW8	TDP1	P78527	PRKDC	S81	S79C	79	Missense	proximal	-2	no	13.261	13.416	PhosphoSitePlus	COSMIC	8.283	Up-regulation
Atypical_PIKK_DNAPK_PRKDC_ST	Q9NUW8	TDP1	P78527	PRKDC	S365	F362L	362	Missense	distal	-3	no	13.129	13.085	EPSD	COSMIC	8.283	Down-regulation
Atypical_PIKK_DNAPK_PRKDC_ST	Q9NUW8	TDP1	P78527	PRKDC	S365	N369D	369	Missense	distal	4	no	13.129	13.105	EPSD	COSMIC	8.283	Down-regulation
Atypical_PIKK_DNAPK_PRKDC_ST	Q9NUW8	TDP1	P78527	PRKDC	S434	P436S	436	Missense	proximal	2	no	9.107	9.338	EPSD	COSMIC	8.283	Up-regulation
Atypical_PIKK_DNAPK_PRKDC_ST	Q9NUW8	TDP1	P78527	PRKDC	S563	A561T	561	Missense	proximal	-2	no	13.591	13.671	EPSD	COSMIC	8.283	Up-regulation
Atypical_PIKK_DNAPK_PRKDC_ST	Q9NUW8	TDP1	P78527	PRKDC	S563	P566L	566	Missense	distal	3	no	13.591	13.256	EPSD	COSMIC;GDSC;CCLE	8.283	Down-regulation
Atypical_PIKK_DNAPK_PRKDC_ST	Q8IZL8	PELP1	P78527	PRKDC	S10	A15V	15	Missense	distal	5	no	10.189	10.011	EPSD	COSMIC	8.283	Down-regulation
Atypical_PIKK_DNAPK_PRKDC_ST	Q8IZL8	PELP1	P78527	PRKDC	S13	P18L	18	Missense	distal	5	no	8.997	8.952	EPSD	COSMIC	8.283	Down-regulation
Atypical_PIKK_DNAPK_PRKDC_ST	Q8IZL8	PELP1	P78527	PRKDC	S13	A15V	15	Missense	proximal	2	no	8.997	7.366	EPSD	COSMIC	8.283	Loss
Atypical_PIKK_DNAPK_PRKDC_ST	Q8IZL8	PELP1	P78527	PRKDC	S251	A248T	248	Missense	distal	-3	no	13.258	13.198	EPSD	COSMIC	8.283	Down-regulation
Atypical_PIKK_DNAPK_PRKDC_ST	Q8IZL8	PELP1	P78527	PRKDC	S477	P478Q	478	Missense	proximal	1	no	6.897	11.378	EPSD	COSMIC	8.283	Gain
Atypical_PIKK_DNAPK_PRKDC_ST	Q8IZL8	PELP1	P78527	PRKDC	S485	P491S	491	Missense	distal	6	no	9.993	9.984	EPSD	COSMIC	8.283	Down-regulation
Atypical_PIKK_DNAPK_PRKDC_ST	Q8IZL8	PELP1	P78527	PRKDC	S485	P478Q	478	Missense	distal	-7	no	9.993	10.790	EPSD	COSMIC	8.283	Up-regulation
Atypical_PIKK_DNAPK_PRKDC_ST	Q8IZL8	PELP1	P78527	PRKDC	S492	P491S	491	Missense	proximal	-1	no	8.975	8.635	EPSD	COSMIC	8.283	Down-regulation
Atypical_PIKK_DNAPK_PRKDC_ST	Q8IZL8	PELP1	P78527	PRKDC	S492	P494H	494	Missense	proximal	2	no	8.975	8.826	EPSD	COSMIC	8.283	Down-regulation
Atypical_PIKK_DNAPK_PRKDC_ST	Q8IZL8	PELP1	P78527	PRKDC	S492	P494T	494	Missense	proximal	2	no	8.975	8.221	EPSD	COSMIC	8.283	Loss
Atypical_PIKK_DNAPK_PRKDC_ST	Q8IZL8	PELP1	P78527	PRKDC	T647	P643H	643	Missense	distal	-4	no	9.452	9.711	EPSD	COSMIC	8.283	Up-regulation
Atypical_PIKK_DNAPK_PRKDC_ST	Q8IZL8	PELP1	P78527	PRKDC	T647	P648A	648	Missense	proximal	1	no	9.452	8.629	EPSD	COSMIC	8.283	Down-regulation
Atypical_PIKK_DNAPK_PRKDC_ST	Q8IZL8	PELP1	P78527	PRKDC	T647	P643S	643	Missense	distal	-4	no	9.452	9.853	EPSD	COSMIC	8.283	Up-regulation
Atypical_PIKK_DNAPK_PRKDC_ST	Q8IZL8	PELP1	P78527	PRKDC	T647	P640L	640	Missense	distal	-7	no	9.452	9.635	EPSD	COSMIC	8.283	Up-regulation
Atypical_PIKK_DNAPK_PRKDC_ST	Q8IZL8	PELP1	P78527	PRKDC	T807	P808Q	808	Missense	proximal	1	no	5.767	10.248	EPSD	COSMIC	8.283	Gain
Atypical_PIKK_DNAPK_PRKDC_ST	Q8IZL8	PELP1	P78527	PRKDC	T981	A985P	985	Missense	distal	4	no	8.457	8.412	EPSD	COSMIC	8.283	Down-regulation
Atypical_PIKK_DNAPK_PRKDC_ST	Q8IZL8	PELP1	P78527	PRKDC	T981	A985T	985	Missense	distal	4	no	8.457	8.397	EPSD	COSMIC	8.283	Down-regulation
Atypical_PIKK_DNAPK_PRKDC_ST	Q8IZL8	PELP1	P78527	PRKDC	T981	A976E	976	Missense	distal	-5	no	8.457	8.612	EPSD	COSMIC	8.283	Up-regulation
Atypical_PIKK_DNAPK_PRKDC_ST	Q8IZL8	PELP1	P78527	PRKDC	S991	A985P	985	Missense	distal	-6	no	10.083	9.676	EPSD	COSMIC	8.283	Down-regulation
Atypical_PIKK_DNAPK_PRKDC_ST	Q8IZL8	PELP1	P78527	PRKDC	S991	A985T	985	Missense	distal	-6	no	10.083	9.693	EPSD	COSMIC	8.283	Down-regulation
Atypical_PIKK_DNAPK_PRKDC_ST	Q8IZL8	PELP1	P78527	PRKDC	S991	E998Q	998	Missense	distal	7	no	10.083	10.179	EPSD	COSMIC	8.283	Up-regulation
Atypical_PIKK_DNAPK_PRKDC_ST	Q8IZL8	PELP1	P78527	PRKDC	T1022	R1018C	1018	Missense	distal	-4	no	8.535	8.369	EPSD	COSMIC	8.283	Down-regulation
Atypical_PIKK_DNAPK_PRKDC_ST	Q8IZL8	PELP1	P78527	PRKDC	T1022	A1020T	1020	Missense	proximal	-2	no	8.535	8.616	EPSD	COSMIC	8.283	Up-regulation
Atypical_PIKK_DNAPK_PRKDC_ST	Q8IZL8	PELP1	P78527	PRKDC	T1022	R1018H	1018	Missense	distal	-4	no	8.535	8.987	EPSD	COSMIC;CCLE	8.283	Up-regulation
Atypical_PIKK_DNAPK_PRKDC_ST	Q8IZL8	PELP1	P78527	PRKDC	T1022	G1019W	1019	Missense	distal	-3	no	8.535	8.298	EPSD	COSMIC	8.283	Down-regulation
Atypical_PIKK_DNAPK_PRKDC_ST	Q8IZL8	PELP1	P78527	PRKDC	T1022	P1028L	1028	Missense	distal	6	no	8.535	8.524	EPSD	COSMIC	8.283	Down-regulation
Atypical_PIKK_DNAPK_PRKDC_ST	Q8IZL8	PELP1	P78527	PRKDC	T1022	G1019V	1019	Missense	distal	-3	no	8.535	8.445	EPSD	COSMIC	8.283	Down-regulation
Atypical_PIKK_DNAPK_PRKDC_ST	Q8IZL8	PELP1	P78527	PRKDC	T1025	R1018C	1018	Missense	distal	-7	no	8.851	8.357	EPSD	COSMIC	8.283	Down-regulation
Atypical_PIKK_DNAPK_PRKDC_ST	Q8IZL8	PELP1	P78527	PRKDC	T1025	A1020T	1020	Missense	distal	-5	no	8.851	8.745	EPSD	COSMIC	8.283	Down-regulation
Atypical_PIKK_DNAPK_PRKDC_ST	Q8IZL8	PELP1	P78527	PRKDC	T1025	R1018H	1018	Missense	distal	-7	no	8.851	9.668	EPSD	COSMIC;CCLE	8.283	Up-regulation
Atypical_PIKK_DNAPK_PRKDC_ST	Q8IZL8	PELP1	P78527	PRKDC	T1025	G1019W	1019	Missense	distal	-6	no	8.851	8.155	EPSD	COSMIC	8.283	Loss
Atypical_PIKK_DNAPK_PRKDC_ST	Q8IZL8	PELP1	P78527	PRKDC	T1025	P1028L	1028	Missense	distal	3	no	8.851	8.516	EPSD	COSMIC	8.283	Down-regulation
Atypical_PIKK_DNAPK_PRKDC_ST	Q8IZL8	PELP1	P78527	PRKDC	T1025	G1019V	1019	Missense	distal	-6	no	8.851	8.433	EPSD	COSMIC	8.283	Down-regulation
Atypical_PIKK_DNAPK_PRKDC_ST	Q8IZL8	PELP1	P78527	PRKDC	S1033	S1033C	1033	Missense	central	0	yes	14.530	0.000	PhosphoSitePlus	COSMIC	8.283	Loss
Atypical_PIKK_DNAPK_PRKDC_ST	Q8IZL8	PELP1	P78527	PRKDC	S1033	S1033F	1033	Missense	central	0	yes	14.530	0.000	PhosphoSitePlus	COSMIC	8.283	Loss
Atypical_PIKK_DNAPK_PRKDC_ST	Q8IZL8	PELP1	P78527	PRKDC	S1033	P1028L	1028	Missense	distal	-5	no	14.530	14.543	PhosphoSitePlus	COSMIC	8.283	Up-regulation
Atypical_PIKK_DNAPK_PRKDC_ST	Q8IZL8	PELP1	P78527	PRKDC	S1033	E1036K	1036	Missense	distal	3	no	14.530	13.972	PhosphoSitePlus	COSMIC	8.283	Down-regulation
Atypical_PIKK_DNAPK_PRKDC_ST	Q8IZL8	PELP1	P78527	PRKDC	S1033	E1040V	1040	Missense	distal	7	no	14.530	13.191	PhosphoSitePlus	COSMIC	8.283	Down-regulation
Atypical_PIKK_DNAPK_PRKDC_ST	Q8IZL8	PELP1	P78527	PRKDC	T1082	P1078L	1078	Missense	distal	-4	no	9.032	8.988	EPSD	COSMIC	8.283	Down-regulation
Atypical_PIKK_DNAPK_PRKDC_ST	Q8IZL8	PELP1	P78527	PRKDC	T1082	E1087Q	1087	Missense	distal	5	no	9.032	9.043	EPSD	COSMIC;CCLE	8.283	Up-regulation
Atypical_PIKK_DNAPK_PRKDC_ST	Q8IZL8	PELP1	P78527	PRKDC	T1082	E1086K	1086	Missense	distal	4	no	9.032	9.019	EPSD	COSMIC	8.283	Down-regulation
Atypical_PIKK_DNAPK_PRKDC_ST	P22415	USF1	P78527	PRKDC	S174	R181S	181	Missense	distal	7	no	10.449	11.606	EPSD	COSMIC	8.283	Up-regulation
Atypical_PIKK_DNAPK_PRKDC_ST	P22415	USF1	P78527	PRKDC	S174	Q175H	175	Missense	proximal	1	no	10.449	0.114	EPSD	COSMIC	8.283	Loss
Atypical_PIKK_DNAPK_PRKDC_ST	P22415	USF1	P78527	PRKDC	S174	V169I	169	Missense	distal	-5	no	10.449	10.137	EPSD	COSMIC	8.283	Down-regulation
Atypical_PIKK_DNAPK_PRKDC_ST	P22415	USF1	P78527	PRKDC	S262	R260C	260	Missense	proximal	-2	no	8.889	8.918	PhosphoSitePlus	COSMIC	8.283	Up-regulation
Atypical_PIKK_DNAPK_PRKDC_ST	P22415	USF1	P78527	PRKDC	S262	R255W	255	Missense	distal	-7	no	8.889	8.081	PhosphoSitePlus	COSMIC	8.283	Loss
Atypical_PIKK_DNAPK_PRKDC_ST	P22415	USF1	P78527	PRKDC	S262	R260H	260	Missense	proximal	-2	no	8.889	8.758	PhosphoSitePlus	COSMIC	8.283	Down-regulation
Atypical_PIKK_DNAPK_PRKDC_ST	P55895	RAG2	P78527	PRKDC	S20	Q27R	27	Missense	distal	7	no	9.161	7.890	EPSD	COSMIC	8.283	Loss
Atypical_PIKK_DNAPK_PRKDC_ST	P55895	RAG2	P78527	PRKDC	S20	N23D	23	Missense	distal	3	no	9.161	9.155	EPSD	COSMIC	8.283	Down-regulation
Atypical_PIKK_DNAPK_PRKDC_ST	P55895	RAG2	P78527	PRKDC	S365	T361R	361	Missense	distal	-4	no	13.045	13.096	PhosphoSitePlus	COSMIC	8.283	Up-regulation
Atypical_PIKK_DNAPK_PRKDC_ST	P55072	VCP	P78527	PRKDC	S457	R453W	453	Missense	distal	-4	no	13.546	13.220	EPSD	COSMIC	8.283	Down-regulation
Atypical_PIKK_DNAPK_PRKDC_ST	P55072	VCP	P78527	PRKDC	S457	L456V	456	Missense	proximal	-1	no	13.546	12.605	EPSD	COSMIC	8.283	Down-regulation
Atypical_PIKK_DNAPK_PRKDC_ST	P55072	VCP	P78527	PRKDC	S459	R465Q	465	Missense	distal	6	no	8.674	8.710	EPSD	COSMIC	8.283	Up-regulation
Atypical_PIKK_DNAPK_PRKDC_ST	P55072	VCP	P78527	PRKDC	S459	R453W	453	Missense	distal	-6	no	8.674	8.187	EPSD	COSMIC	8.283	Loss
Atypical_PIKK_DNAPK_PRKDC_ST	P55072	VCP	P78527	PRKDC	S459	L456V	456	Missense	distal	-3	no	8.674	8.489	EPSD	COSMIC	8.283	Down-regulation
Atypical_PIKK_DNAPK_PRKDC_ST	P55072	VCP	P78527	PRKDC	T761	R766Q	766	Missense	distal	5	no	7.983	8.305	EPSD	COSMIC;CCLE	8.283	Gain
Atypical_PIKK_DNAPK_PRKDC_ST	P55072	VCP	P78527	PRKDC	S765	R766Q	766	Missense	proximal	1	no	0.894	11.309	EPSD	COSMIC;CCLE	8.283	Gain
Atypical_PIKK_DNAPK_PRKDC_ST	P55072	VCP	P78527	PRKDC	S784	T791P	791	Missense	distal	7	no	12.020	12.740	PhosphoSitePlus	COSMIC	8.283	Up-regulation
Atypical_PIKK_DNAPK_PRKDC_ST	P52945	PDX1	P78527	PRKDC	S273	S266R	266	Missense	distal	-7	no	9.610	8.943	EPSD	COSMIC;CCLE	8.283	Down-regulation
Atypical_PIKK_DNAPK_PRKDC_ST	Q8TCS8	PNPT1	P78527	PRKDC	S93	P90H	90	Missense	distal	-3	no	10.215	10.220	EPSD	COSMIC	8.283	Up-regulation
Atypical_PIKK_DNAPK_PRKDC_ST	Q8TCS8	PNPT1	P78527	PRKDC	S93	P90L	90	Missense	distal	-3	no	10.215	10.015	EPSD	COSMIC	8.283	Down-regulation
Atypical_PIKK_DNAPK_PRKDC_ST	Q8TCS8	PNPT1	P78527	PRKDC	S280	P273H	273	Missense	distal	-7	no	9.559	10.360	EPSD	COSMIC	8.283	Up-regulation
Atypical_PIKK_DNAPK_PRKDC_ST	Q8TCS8	PNPT1	P78527	PRKDC	S339	F340Y	340	Missense	proximal	1	no	9.342	12.205	EPSD	COSMIC	8.283	Up-regulation
Atypical_PIKK_DNAPK_PRKDC_ST	Q8TCS8	PNPT1	P78527	PRKDC	S339	P333L	333	Missense	distal	-6	no	9.342	9.461	EPSD	COSMIC;GDSC;CCLE	8.283	Up-regulation
Atypical_PIKK_DNAPK_PRKDC_ST	Q8TCS8	PNPT1	P78527	PRKDC	S339	E346Q	346	Missense	distal	7	no	9.342	9.438	EPSD	COSMIC;GDSC;CCLE	8.283	Up-regulation
Atypical_PIKK_DNAPK_PRKDC_ST	P11387	TOP1	P78527	PRKDC	S10	L6F	6	Missense	distal	-4	no	13.022	12.951	PhosphoSitePlus	COSMIC	8.283	Down-regulation
Atypical_PIKK_DNAPK_PRKDC_ST	P11387	TOP1	P78527	PRKDC	S10	D9G	9	Missense	proximal	-1	no	13.022	12.008	PhosphoSitePlus	COSMIC	8.283	Down-regulation
Atypical_PIKK_DNAPK_PRKDC_ST	P11387	TOP1	P78527	PRKDC	S10	L6V	6	Missense	distal	-4	no	13.022	12.640	PhosphoSitePlus	COSMIC	8.283	Down-regulation
Atypical_PIKK_DNAPK_PRKDC_ST	P11387	TOP1	P78527	PRKDC	S21	H22Q	22	Missense	proximal	1	no	4.657	14.992	EPSD	COSMIC	8.283	Gain
Atypical_PIKK_DNAPK_PRKDC_ST	P11387	TOP1	P78527	PRKDC	S112	G109V	109	Missense	distal	-3	no	11.151	11.061	EPSD	COSMIC;GDSC;CCLE	8.283	Down-regulation
Atypical_PIKK_DNAPK_PRKDC_ST	P11387	TOP1	P78527	PRKDC	T303	F309L	309	Missense	distal	6	no	11.969	11.964	EPSD	COSMIC	8.283	Down-regulation
Atypical_PIKK_DNAPK_PRKDC_ST	P11387	TOP1	P78527	PRKDC	T303	N296S	296	Missense	distal	-7	no	11.969	12.285	EPSD	COSMIC;GDSC	8.283	Up-regulation
TKL_MLK_LZK_MAP3K12_ST	O14950	MYL12B	Q12852	MAP3K12	T19	M25L	25	Missense	distal	6	no	4.536	4.354	EPSD;PhosphoSitePlus	COSMIC	1.313	Down-regulation
TKL_MLK_LZK_MAP3K12_ST	O14950	MYL12B	Q12852	MAP3K12	T19	K12N	12	Missense	distal	-7	no	4.536	4.304	EPSD;PhosphoSitePlus	COSMIC	1.313	Down-regulation
TKL_MLK_LZK_MAP3K12_ST	O14950	MYL12B	Q12852	MAP3K12	S20	M25L	25	Missense	distal	5	no	4.000	3.871	PhosphoSitePlus;EPSD	COSMIC	1.313	Down-regulation
TKL_MLK_LZK_MAP3K12_ST	O14950	MYL12B	Q12852	MAP3K12	T129	L123I	123	Missense	distal	-6	no	1.656	1.661	EPSD	COSMIC	1.313	Up-regulation
AGC_PKN_PKN1_ST	P10636	MAPT	Q16512	PKN1	S64	E62K	62	Missense	proximal	-2	no	61.972	70.912	EPSD	COSMIC	59.390	Up-regulation
AGC_PKN_PKN1_ST	P10636	MAPT	Q16512	PKN1	T167	P160Q	160	Missense	distal	-7	no	80.887	81.125	EPSD	COSMIC	59.390	Up-regulation
AGC_PKN_PKN1_ST	P10636	MAPT	Q16512	PKN1	T167	A166V	166	Missense	proximal	-1	no	80.887	81.076	EPSD	COSMIC;CCLE	59.390	Up-regulation
AGC_PKN_PKN1_ST	P10636	MAPT	Q16512	PKN1	T167	E165K	165	Missense	proximal	-2	no	80.887	89.827	EPSD	COSMIC	59.390	Up-regulation
AGC_PKN_PKN1_ST	P10636	MAPT	Q16512	PKN1	T167	P160S	160	Missense	distal	-7	no	80.887	80.928	EPSD	COSMIC	59.390	Up-regulation
AGC_PKN_PKN1_ST	P10636	MAPT	Q16512	PKN1	T167	G172V	172	Missense	distal	5	no	80.887	81.056	EPSD	COSMIC	59.390	Up-regulation
AGC_PKN_PKN1_ST	P10636	MAPT	Q16512	PKN1	S171	P175S	175	Missense	distal	4	no	79.050	82.493	EPSD	COSMIC	59.390	Up-regulation
AGC_PKN_PKN1_ST	P10636	MAPT	Q16512	PKN1	S171	A166V	166	Missense	distal	-5	no	79.050	78.934	EPSD	COSMIC;CCLE	59.390	Down-regulation
AGC_PKN_PKN1_ST	P10636	MAPT	Q16512	PKN1	S171	E176G	176	Missense	distal	5	no	79.050	79.145	EPSD	COSMIC	59.390	Up-regulation
AGC_PKN_PKN1_ST	P10636	MAPT	Q16512	PKN1	S171	D177G	177	Missense	distal	6	no	79.050	79.124	EPSD	COSMIC	59.390	Up-regulation
AGC_PKN_PKN1_ST	P10636	MAPT	Q16512	PKN1	S171	E165K	165	Missense	distal	-6	no	79.050	80.941	EPSD	COSMIC	59.390	Up-regulation
AGC_PKN_PKN1_ST	P10636	MAPT	Q16512	PKN1	S171	G172V	172	Missense	proximal	1	no	79.050	75.552	EPSD	COSMIC	59.390	Down-regulation
AGC_PKN_PKN1_ST	P10636	MAPT	Q16512	PKN1	S214	E210Q	210	Missense	distal	-4	no	64.058	71.063	EPSD;PhosphoSitePlus	COSMIC	59.390	Up-regulation
AGC_PKN_PKN1_ST	P10636	MAPT	Q16512	PKN1	S214	G207E	207	Missense	distal	-7	no	64.058	64.251	EPSD;PhosphoSitePlus	COSMIC	59.390	Up-regulation
AGC_PKN_PKN1_ST	P10636	MAPT	Q16512	PKN1	S369	V368I	368	Missense	proximal	-1	no	64.889	67.134	EPSD	COSMIC	59.390	Up-regulation
AGC_PKN_PKN1_ST	P10636	MAPT	Q16512	PKN1	S369	R370W	370	Missense	proximal	1	no	64.889	66.081	EPSD	COSMIC	59.390	Up-regulation
AGC_PKN_PKN1_ST	P10636	MAPT	Q16512	PKN1	T386	G385V	385	Missense	proximal	-1	no	72.789	72.518	EPSD	COSMIC	59.390	Down-regulation
AGC_PKN_PKN1_ST	P10636	MAPT	Q16512	PKN1	T386	T386I	386	Missense	central	0	yes	72.789	0.000	EPSD	COSMIC	59.390	Loss
AGC_PKN_PKN1_ST	P10636	MAPT	Q16512	PKN1	T386	D389N	389	Missense	distal	3	no	72.789	73.183	EPSD	COSMIC;GDSC;CCLE	59.390	Up-regulation
AGC_PKN_PKN1_ST	P10636	MAPT	Q16512	PKN1	S400	R398C	398	Missense	proximal	-2	no	76.145	56.924	EPSD	COSMIC	59.390	Loss
AGC_PKN_PKN1_ST	P10636	MAPT	Q16512	PKN1	S400	S396F	396	Missense	distal	-4	no	76.145	72.705	EPSD	COSMIC	59.390	Down-regulation
AGC_PKN_PKN1_ST	P10636	MAPT	Q16512	PKN1	T403	L410F	410	Missense	distal	7	no	65.263	65.294	EPSD	COSMIC	59.390	Up-regulation
AGC_PKN_PKN1_ST	P10636	MAPT	Q16512	PKN1	T403	R398C	398	Missense	distal	-5	no	65.263	63.473	EPSD	COSMIC	59.390	Down-regulation
AGC_PKN_PKN1_ST	P10636	MAPT	Q16512	PKN1	T403	S396F	396	Missense	distal	-7	no	65.263	65.161	EPSD	COSMIC	59.390	Down-regulation
AGC_PKN_PKN1_ST	P10636	MAPT	Q16512	PKN1	T416	L410F	410	Missense	distal	-6	no	83.277	84.354	EPSD	COSMIC	59.390	Up-regulation
AGC_PKN_PKN1_ST	P10636	MAPT	Q16512	PKN1	T416	P412S	412	Missense	distal	-4	no	83.277	85.380	EPSD	COSMIC	59.390	Up-regulation
AGC_PKN_PKN1_ST	P10636	MAPT	Q16512	PKN1	S451	S447P	447	Missense	distal	-4	no	63.672	61.569	EPSD	COSMIC	59.390	Down-regulation
AGC_PKN_PKN1_ST	P10636	MAPT	Q16512	PKN1	S451	R448Q	448	Missense	distal	-3	no	63.672	53.990	EPSD	COSMIC	59.390	Loss
AGC_PKN_PKN1_ST	P10636	MAPT	Q16512	PKN1	T470	T466M	466	Missense	distal	-4	no	67.800	68.335	EPSD	COSMIC;GDSC;CCLE	59.390	Up-regulation
AGC_PKN_PKN1_ST	P10636	MAPT	Q16512	PKN1	T470	K467T	467	Missense	distal	-3	no	67.800	77.064	EPSD	COSMIC	59.390	Up-regulation
AGC_PKN_PKN1_ST	P10636	MAPT	Q16512	PKN1	T470	P477L	477	Missense	distal	7	no	67.800	67.429	EPSD	COSMIC	59.390	Down-regulation
AGC_PKN_PKN1_ST	P10636	MAPT	Q16512	PKN1	T470	P477S	477	Missense	distal	7	no	67.800	67.849	EPSD	COSMIC	59.390	Up-regulation
AGC_PKN_PKN1_ST	P10636	MAPT	Q16512	PKN1	T486	R487K	487	Missense	proximal	1	no	59.274	60.901	EPSD	COSMIC	59.390	Gain
AGC_PKN_PKN1_ST	P10636	MAPT	Q16512	PKN1	T486	K491R	491	Missense	distal	5	no	59.274	59.662	EPSD	COSMIC	59.390	Gain
AGC_PKN_PKN1_ST	P10636	MAPT	Q16512	PKN1	T486	R487G	487	Missense	proximal	1	no	59.274	60.205	EPSD	COSMIC	59.390	Gain
AGC_PKN_PKN1_ST	P10636	MAPT	Q16512	PKN1	T498	K491R	491	Missense	distal	-7	no	59.929	59.986	EPSD	COSMIC	59.390	Up-regulation
AGC_PKN_PKN1_ST	P10636	MAPT	Q16512	PKN1	T498	A495T	495	Missense	distal	-3	no	59.929	66.109	EPSD	COSMIC	59.390	Up-regulation
AGC_PKN_PKN1_ST	P10636	MAPT	Q16512	PKN1	T498	P493L	493	Missense	distal	-5	no	59.929	61.039	EPSD	COSMIC	59.390	Up-regulation
AGC_PKN_PKN1_ST	P10636	MAPT	Q16512	PKN1	S502	P506S	506	Missense	distal	4	no	60.365	63.807	EPSD	COSMIC	59.390	Up-regulation
AGC_PKN_PKN1_ST	P10636	MAPT	Q16512	PKN1	S502	A495T	495	Missense	distal	-7	no	60.365	60.398	EPSD	COSMIC	59.390	Up-regulation
AGC_PKN_PKN1_ST	P10636	MAPT	Q16512	PKN1	S502	G509V	509	Missense	distal	7	no	60.365	60.316	EPSD	COSMIC	59.390	Down-regulation
AGC_PKN_PKN1_ST	P10636	MAPT	Q16512	PKN1	S502	P506L	506	Missense	distal	4	no	60.365	62.109	EPSD	COSMIC	59.390	Up-regulation
AGC_PKN_PKN1_ST	P10636	MAPT	Q16512	PKN1	S515	G521V	521	Missense	distal	6	no	68.334	68.348	EPSD	COSMIC	59.390	Up-regulation
AGC_PKN_PKN1_ST	P10636	MAPT	Q16512	PKN1	S515	G518V	518	Missense	distal	3	no	68.334	67.044	EPSD	COSMIC	59.390	Down-regulation
AGC_PKN_PKN1_ST	P10636	MAPT	Q16512	PKN1	S515	R511C	511	Missense	distal	-4	no	68.334	62.303	EPSD	COSMIC;CCLE	59.390	Down-regulation
AGC_PKN_PKN1_ST	P10636	MAPT	Q16512	PKN1	S515	G509V	509	Missense	distal	-6	no	68.334	67.938	EPSD	COSMIC	59.390	Down-regulation
AGC_PKN_PKN1_ST	P10636	MAPT	Q16512	PKN1	S525	G521V	521	Missense	distal	-4	no	66.199	64.221	EPSD	COSMIC	59.390	Down-regulation
AGC_PKN_PKN1_ST	P10636	MAPT	Q16512	PKN1	S525	R526H	526	Missense	proximal	1	no	66.199	57.616	EPSD	COSMIC	59.390	Loss
AGC_PKN_PKN1_ST	P10636	MAPT	Q16512	PKN1	S525	G518V	518	Missense	distal	-7	no	66.199	66.310	EPSD	COSMIC	59.390	Up-regulation
AGC_PKN_PKN1_ST	P10636	MAPT	Q16512	PKN1	S525	R528S	528	Missense	distal	3	no	66.199	65.848	EPSD	COSMIC	59.390	Down-regulation
AGC_PKN_PKN1_ST	P10636	MAPT	Q16512	PKN1	S525	P530S	530	Missense	distal	5	no	66.199	66.401	EPSD	COSMIC	59.390	Up-regulation
AGC_PKN_PKN1_ST	P10636	MAPT	Q16512	PKN1	T529	R526H	526	Missense	distal	-3	no	60.583	39.521	EPSD	COSMIC	59.390	Loss
AGC_PKN_PKN1_ST	P10636	MAPT	Q16512	PKN1	T529	R528S	528	Missense	proximal	-1	no	60.583	62.954	EPSD	COSMIC	59.390	Up-regulation
AGC_PKN_PKN1_ST	P10636	MAPT	Q16512	PKN1	T529	P530S	530	Missense	proximal	1	no	60.583	54.278	EPSD	COSMIC	59.390	Loss
AGC_PKN_PKN1_ST	P10636	MAPT	Q16512	PKN1	T529	P536H	536	Missense	distal	7	no	60.583	60.222	EPSD	COSMIC	59.390	Down-regulation
AGC_PKN_PKN1_ST	P10636	MAPT	Q16512	PKN1	T529	P535Q	535	Missense	distal	6	no	60.583	60.281	EPSD	COSMIC	59.390	Down-regulation
AGC_PKN_PKN1_ST	P10636	MAPT	Q16512	PKN1	S531	R526H	526	Missense	distal	-5	no	86.612	85.505	EPSD	COSMIC	59.390	Down-regulation
AGC_PKN_PKN1_ST	P10636	MAPT	Q16512	PKN1	S531	R528S	528	Missense	distal	-3	no	86.612	71.782	EPSD	COSMIC	59.390	Down-regulation
AGC_PKN_PKN1_ST	P10636	MAPT	Q16512	PKN1	S531	P530S	530	Missense	proximal	-1	no	86.612	84.729	EPSD	COSMIC	59.390	Down-regulation
AGC_PKN_PKN1_ST	P10636	MAPT	Q16512	PKN1	S531	P536H	536	Missense	distal	5	no	86.612	86.539	EPSD	COSMIC	59.390	Down-regulation
AGC_PKN_PKN1_ST	P10636	MAPT	Q16512	PKN1	S531	P535Q	535	Missense	distal	4	no	86.612	93.641	EPSD	COSMIC	59.390	Up-regulation
AGC_PKN_PKN1_ST	P10636	MAPT	Q16512	PKN1	T534	R528S	528	Missense	distal	-6	no	69.438	69.344	EPSD	COSMIC	59.390	Down-regulation
AGC_PKN_PKN1_ST	P10636	MAPT	Q16512	PKN1	T534	P530S	530	Missense	distal	-4	no	69.438	71.541	EPSD	COSMIC	59.390	Up-regulation
AGC_PKN_PKN1_ST	P10636	MAPT	Q16512	PKN1	T534	P536H	536	Missense	proximal	2	no	69.438	68.312	EPSD	COSMIC	59.390	Down-regulation
AGC_PKN_PKN1_ST	P10636	MAPT	Q16512	PKN1	T534	P535Q	535	Missense	proximal	1	no	69.438	63.944	EPSD	COSMIC	59.390	Down-regulation
AGC_PKN_PKN1_ST	P10636	MAPT	Q16512	PKN1	T534	E539Q	539	Missense	distal	5	no	69.438	69.749	EPSD	COSMIC	59.390	Up-regulation
AGC_PKN_PKN1_ST	P10636	MAPT	Q16512	PKN1	T537	P530S	530	Missense	distal	-7	no	66.981	67.023	EPSD	COSMIC	59.390	Up-regulation
AGC_PKN_PKN1_ST	P10636	MAPT	Q16512	PKN1	T537	P536H	536	Missense	proximal	-1	no	66.981	65.371	EPSD	COSMIC	59.390	Down-regulation
AGC_PKN_PKN1_ST	P10636	MAPT	Q16512	PKN1	T537	P535Q	535	Missense	proximal	-2	no	66.981	72.547	EPSD	COSMIC	59.390	Up-regulation
AGC_PKN_PKN1_ST	P10636	MAPT	Q16512	PKN1	T537	E539Q	539	Missense	proximal	2	no	66.981	71.677	EPSD	COSMIC	59.390	Up-regulation
AGC_PKN_PKN1_ST	P10636	MAPT	Q16512	PKN1	S554	S555F	555	Missense	proximal	1	no	47.338	63.949	EPSD	COSMIC	59.390	Gain
AGC_PKN_PKN1_ST	P10636	MAPT	Q16512	PKN1	S558	V565M	565	Missense	distal	7	no	69.690	69.566	EPSD	COSMIC	59.390	Down-regulation
AGC_PKN_PKN1_ST	P10636	MAPT	Q16512	PKN1	S558	R559C	559	Missense	proximal	1	no	69.690	67.974	EPSD	COSMIC	59.390	Down-regulation
AGC_PKN_PKN1_ST	P10636	MAPT	Q16512	PKN1	S558	P553R	553	Missense	distal	-5	no	69.690	71.097	EPSD	COSMIC	59.390	Up-regulation
AGC_PKN_PKN1_ST	P10636	MAPT	Q16512	PKN1	S558	P553L	553	Missense	distal	-5	no	69.690	70.800	EPSD	COSMIC	59.390	Up-regulation
AGC_PKN_PKN1_ST	P10636	MAPT	Q16512	PKN1	S558	S555F	555	Missense	distal	-3	no	69.690	67.686	EPSD	COSMIC	59.390	Down-regulation
AGC_PKN_PKN1_ST	P10636	MAPT	Q16512	PKN1	S558	P553Q	553	Missense	distal	-5	no	69.690	69.485	EPSD	COSMIC	59.390	Down-regulation
AGC_PKN_PKN1_ST	P10636	MAPT	Q16512	PKN1	T562	V565M	565	Missense	distal	3	no	75.943	74.907	EPSD	COSMIC	59.390	Down-regulation
AGC_PKN_PKN1_ST	P10636	MAPT	Q16512	PKN1	T562	P566S	566	Missense	distal	4	no	75.943	79.386	EPSD	COSMIC	59.390	Up-regulation
AGC_PKN_PKN1_ST	P10636	MAPT	Q16512	PKN1	T562	R559C	559	Missense	distal	-3	no	75.943	-0.920	EPSD	COSMIC	59.390	Loss
AGC_PKN_PKN1_ST	P10636	MAPT	Q16512	PKN1	T562	S555F	555	Missense	distal	-7	no	75.943	75.841	EPSD	COSMIC	59.390	Down-regulation
AGC_PKN_PKN1_ST	P10636	MAPT	Q16512	PKN1	T562	P568S	568	Missense	distal	6	no	75.943	75.935	EPSD	COSMIC	59.390	Down-regulation
AGC_PKN_PKN1_ST	P10636	MAPT	Q16512	PKN1	S575	T580N	580	Missense	distal	5	no	81.707	81.938	EPSD	COSMIC	59.390	Up-regulation
AGC_PKN_PKN1_ST	P10636	MAPT	Q16512	PKN1	S575	G578S	578	Missense	distal	3	no	81.707	80.933	EPSD	COSMIC	59.390	Down-regulation
AGC_PKN_PKN1_ST	P10636	MAPT	Q16512	PKN1	S575	K571E	571	Missense	distal	-4	no	81.707	78.006	EPSD	COSMIC	59.390	Down-regulation
AGC_PKN_PKN1_ST	P10636	MAPT	Q16512	PKN1	S575	P568S	568	Missense	distal	-7	no	81.707	81.748	EPSD	COSMIC	59.390	Up-regulation
AGC_PKN_PKN1_ST	P10636	MAPT	Q16512	PKN1	S606	N613D	613	Missense	distal	7	no	79.897	80.161	EPSD	COSMIC	59.390	Up-regulation
AGC_PKN_PKN1_ST	P10636	MAPT	Q16512	PKN1	S606	S602G	602	Missense	distal	-4	no	79.897	78.545	EPSD	COSMIC	59.390	Down-regulation
AGC_PKN_PKN1_ST	P10636	MAPT	Q16512	PKN1	S606	C608W	608	Missense	proximal	2	no	79.897	81.213	EPSD	COSMIC	59.390	Up-regulation
AGC_PKN_PKN1_ST	P10636	MAPT	Q16512	PKN1	S606	S610L	610	Missense	distal	4	no	79.897	78.199	EPSD	COSMIC	59.390	Down-regulation
AGC_PKN_PKN1_ST	P10636	MAPT	Q16512	PKN1	S606	D600E	600	Missense	distal	-6	no	79.897	79.022	EPSD	COSMIC	59.390	Down-regulation
AGC_PKN_PKN1_ST	P10636	MAPT	Q16512	PKN1	S637	S633N	633	Missense	distal	-4	no	88.507	86.968	EPSD	COSMIC	59.390	Down-regulation
AGC_PKN_PKN1_ST	P10636	MAPT	Q16512	PKN1	S637	S633I	633	Missense	distal	-4	no	88.507	84.135	EPSD	COSMIC	59.390	Down-regulation
AGC_PKN_PKN1_ST	P10636	MAPT	Q16512	PKN1	S669	S669L	669	Missense	central	0	yes	86.037	0.000	EPSD	COSMIC	59.390	Loss
AGC_PKN_PKN1_ST	P10636	MAPT	Q16512	PKN1	S669	R666K	666	Missense	distal	-3	no	86.037	67.902	EPSD	COSMIC	59.390	Down-regulation
AGC_PKN_PKN1_ST	P10636	MAPT	Q16512	PKN1	S669	D662G	662	Missense	distal	-7	no	86.037	86.049	EPSD	COSMIC	59.390	Up-regulation
AGC_PKN_PKN1_ST	P10636	MAPT	Q16512	PKN1	S669	S673F	673	Missense	distal	4	no	86.037	69.493	EPSD	COSMIC	59.390	Down-regulation
AGC_PKN_PKN1_ST	P10636	MAPT	Q16512	PKN1	S669	K670N	670	Missense	proximal	1	no	86.037	81.852	EPSD	COSMIC	59.390	Down-regulation
AGC_PKN_PKN1_ST	P10636	MAPT	Q16512	PKN1	S669	K664N	664	Missense	distal	-5	no	86.037	84.328	EPSD	COSMIC	59.390	Down-regulation
AGC_PKN_PKN1_ST	P10636	MAPT	Q16512	PKN1	S669	L674Q	674	Missense	distal	5	no	86.037	85.826	EPSD	COSMIC	59.390	Down-regulation
AGC_PKN_PKN1_ST	P10636	MAPT	Q16512	PKN1	T703	R696H	696	Missense	distal	-7	no	61.806	61.877	EPSD	COSMIC	59.390	Up-regulation
AGC_PKN_PKN1_ST	P10636	MAPT	Q16512	PKN1	T703	E708D	708	Missense	distal	5	no	61.806	62.000	EPSD	COSMIC	59.390	Up-regulation
AGC_PKN_PKN1_ST	P10636	MAPT	Q16512	PKN1	T703	G706R	706	Missense	distal	3	no	61.806	61.384	EPSD	COSMIC	59.390	Down-regulation
AGC_PKN_PKN1_ST	P10636	MAPT	Q16512	PKN1	T703	V710M	710	Missense	distal	7	no	61.806	61.682	EPSD	COSMIC	59.390	Down-regulation
AGC_PKN_PKN1_ST	P10636	MAPT	Q16512	PKN1	T703	E708K	708	Missense	distal	5	no	61.806	62.333	EPSD	COSMIC	59.390	Up-regulation
AGC_PKN_PKN1_ST	P10636	MAPT	Q16512	PKN1	T703	R696C	696	Missense	distal	-7	no	61.806	61.980	EPSD	COSMIC	59.390	Up-regulation
AGC_PKN_PKN1_ST	P10636	MAPT	Q16512	PKN1	T703	V710A	710	Missense	distal	7	no	61.806	61.628	EPSD	COSMIC	59.390	Down-regulation
AGC_PKN_PKN1_ST	P10636	MAPT	Q16512	PKN1	T703	T703I	703	Missense	central	0	yes	61.806	0.000	EPSD	COSMIC	59.390	Loss
AGC_PKN_PKN1_ST	P10636	MAPT	Q16512	PKN1	S726	G732S	732	Missense	distal	6	no	69.247	69.306	EPSD	COSMIC	59.390	Up-regulation
AGC_PKN_PKN1_ST	P10636	MAPT	Q16512	PKN1	S726	G732C	732	Missense	distal	6	no	69.247	68.613	EPSD	COSMIC	59.390	Down-regulation
AGC_PKN_PKN1_ST	P10636	MAPT	Q16512	PKN1	S726	R723W	723	Missense	distal	-3	no	69.247	27.815	EPSD	COSMIC	59.390	Loss
AGC_PKN_PKN1_ST	P10636	MAPT	Q16512	PKN1	S726	V728M	728	Missense	proximal	2	no	69.247	70.652	EPSD	COSMIC	59.390	Up-regulation
AGC_PKN_PKN1_ST	P10636	MAPT	Q16512	PKN1	S726	V728A	728	Missense	proximal	2	no	69.247	70.675	EPSD	COSMIC	59.390	Up-regulation
AGC_PKN_PKN1_ST	P00533	EGFR	Q16512	PKN1	S246	R252G	252	Missense	distal	6	no	63.581	62.860	EPSD	COSMIC	59.390	Down-regulation
AGC_PKN_PKN1_ST	P00533	EGFR	Q16512	PKN1	S246	C251Y	251	Missense	distal	5	no	63.581	63.868	EPSD	COSMIC;GDSC;CCLE	59.390	Up-regulation
AGC_PKN_PKN1_ST	P00533	EGFR	Q16512	PKN1	S246	S246R	246	Missense	central	0	yes	63.581	0.000	EPSD	COSMIC	59.390	Loss
AGC_PKN_PKN1_ST	P00533	EGFR	Q16512	PKN1	S246	D247Y	247	Missense	proximal	1	no	63.581	60.108	EPSD	COSMIC	59.390	Down-regulation
AGC_PKN_PKN1_ST	P00533	EGFR	Q16512	PKN1	S246	G239C	239	Missense	distal	-7	no	63.581	63.742	EPSD	COSMIC	59.390	Up-regulation
AGC_PKN_PKN1_ST	P00533	EGFR	Q16512	PKN1	S246	L249V	249	Missense	distal	3	no	63.581	62.874	EPSD	COSMIC	59.390	Down-regulation
AGC_PKN_PKN1_ST	P00533	EGFR	Q16512	PKN1	S246	P243S	243	Missense	distal	-3	no	63.581	65.664	EPSD	COSMIC	59.390	Up-regulation
AGC_PKN_PKN1_ST	P00533	EGFR	Q16512	PKN1	S246	P243A	243	Missense	distal	-3	no	63.581	65.443	EPSD	COSMIC	59.390	Up-regulation
AGC_PKN_PKN1_ST	P00533	EGFR	Q16512	PKN1	T648	G652R	652	Missense	distal	4	no	54.528	71.301	EPSD	COSMIC	59.390	Gain
AGC_PKN_PKN1_ST	P00533	EGFR	Q16512	PKN1	T678	R680Q	680	Missense	proximal	2	no	83.114	81.625	PhosphoSitePlus	COSMIC	59.390	Down-regulation
AGC_PKN_PKN1_ST	P00533	EGFR	Q16512	PKN1	T678	V674F	674	Missense	distal	-4	no	83.114	83.006	PhosphoSitePlus	COSMIC	59.390	Down-regulation
AGC_PKN_PKN1_ST	P00533	EGFR	Q16512	PKN1	T678	R675Q	675	Missense	distal	-3	no	83.114	73.432	PhosphoSitePlus	COSMIC;GDSC	59.390	Down-regulation
AGC_PKN_PKN1_ST	P00533	EGFR	Q16512	PKN1	T678	R680W	680	Missense	proximal	2	no	83.114	80.975	PhosphoSitePlus	COSMIC	59.390	Down-regulation
AGC_PKN_PKN1_ST	P00533	EGFR	Q16512	PKN1	T678	H672Y	672	Missense	distal	-6	no	83.114	83.001	PhosphoSitePlus	COSMIC	59.390	Down-regulation
AGC_PKN_PKN1_ST	P00533	EGFR	Q16512	PKN1	T678	R680G	680	Missense	proximal	2	no	83.114	82.711	PhosphoSitePlus	COSMIC	59.390	Down-regulation
AGC_PKN_PKN1_ST	P00533	EGFR	Q16512	PKN1	T678	K676R	676	Missense	proximal	-2	no	83.114	92.518	PhosphoSitePlus	COSMIC	59.390	Up-regulation
AGC_PKN_PKN1_ST	P00533	EGFR	Q16512	PKN1	T678	R671C	671	Missense	distal	-7	no	83.114	83.288	PhosphoSitePlus	COSMIC	59.390	Up-regulation
AGC_PKN_PKN1_ST	P00533	EGFR	Q16512	PKN1	T678	R677C	677	Missense	proximal	-1	no	83.114	89.224	PhosphoSitePlus	COSMIC;GDSC;CCLE	59.390	Up-regulation
AGC_PKN_PKN1_ST	P00533	EGFR	Q16512	PKN1	T678	R671H	671	Missense	distal	-7	no	83.114	83.185	PhosphoSitePlus	COSMIC	59.390	Up-regulation
AGC_PKN_PKN1_ST	P00533	EGFR	Q16512	PKN1	T892	H893R	893	Missense	proximal	1	no	57.284	65.867	EPSD	COSMIC	59.390	Gain
AGC_PKN_PKN1_ST	P00533	EGFR	Q16512	PKN1	T1032	S1025T	1025	Missense	distal	-7	no	60.397	60.428	EPSD	COSMIC	59.390	Up-regulation
AGC_PKN_PKN1_ST	P00533	EGFR	Q16512	PKN1	T1032	P1027S	1027	Missense	distal	-5	no	60.397	60.659	EPSD	COSMIC	59.390	Up-regulation
AGC_PKN_PKN1_ST	P00533	EGFR	Q16512	PKN1	T1032	S1036R	1036	Missense	distal	4	no	60.397	65.304	EPSD	COSMIC	59.390	Up-regulation
AGC_PKN_PKN1_ST	P00533	EGFR	Q16512	PKN1	T1032	S1028L	1028	Missense	distal	-4	no	60.397	58.253	EPSD	COSMIC	59.390	Loss
AGC_PKN_PKN1_ST	P00533	EGFR	Q16512	PKN1	T1032	L1034I	1034	Missense	proximal	2	no	60.397	60.135	EPSD	COSMIC	59.390	Down-regulation
AGC_PKN_PKN1_ST	P00533	EGFR	Q16512	PKN1	S1039	S1036R	1036	Missense	distal	-3	no	51.326	66.156	EPSD	COSMIC	59.390	Gain
AGC_PKN_PKN1_ST	P00533	EGFR	Q16512	PKN1	S1070	F1065L	1065	Missense	distal	-5	no	61.483	61.677	EPSD	COSMIC	59.390	Up-regulation
AGC_PKN_PKN1_ST	P00533	EGFR	Q16512	PKN1	S1070	G1075D	1075	Missense	distal	5	no	61.483	61.582	EPSD	COSMIC	59.390	Up-regulation
AGC_PKN_PKN1_ST	P00533	EGFR	Q16512	PKN1	S1070	Q1067L	1067	Missense	distal	-3	no	61.483	53.892	EPSD	COSMIC	59.390	Loss
AGC_PKN_PKN1_ST	P00533	EGFR	Q16512	PKN1	S1070	Y1069C	1069	Missense	proximal	-1	no	61.483	63.148	EPSD	COSMIC;GDSC;CCLE	59.390	Up-regulation
AGC_PKN_PKN1_ST	P00533	EGFR	Q16512	PKN1	S1070	S1064G	1064	Missense	distal	-6	no	61.483	61.990	EPSD	COSMIC	59.390	Up-regulation
AGC_PKN_PKN1_ST	P00533	EGFR	Q16512	PKN1	S1070	S1071L	1071	Missense	proximal	1	no	61.483	68.185	EPSD	COSMIC	59.390	Up-regulation
AGC_PKN_PKN1_ST	P00533	EGFR	Q16512	PKN1	S1070	S1064R	1064	Missense	distal	-6	no	61.483	61.577	EPSD	COSMIC	59.390	Up-regulation
AGC_PKN_PKN1_ST	P00533	EGFR	Q16512	PKN1	S1070	S1064N	1064	Missense	distal	-6	no	61.483	62.477	EPSD	COSMIC	59.390	Up-regulation
AGC_PKN_PKN1_ST	P00533	EGFR	Q16512	PKN1	S1120	H1124Q	1124	Missense	distal	4	no	57.685	69.354	EPSD	COSMIC;CCLE	59.390	Gain
AGC_PKN_PKN1_ST	P00533	EGFR	Q16512	PKN1	T1145	V1147I	1147	Missense	proximal	2	no	58.821	60.359	EPSD	COSMIC	59.390	Gain
AGC_PKN_PKN1_ST	P00533	EGFR	Q16512	PKN1	S1162	A1155D	1155	Missense	distal	-7	no	60.254	60.169	EPSD	COSMIC	59.390	Down-regulation
AGC_PKN_PKN1_ST	P00533	EGFR	Q16512	PKN1	S1162	S1162N	1162	Missense	central	0	yes	60.254	0.000	EPSD	COSMIC	59.390	Loss
AGC_PKN_PKN1_ST	P00533	EGFR	Q16512	PKN1	S1162	Q1159H	1159	Missense	distal	-3	no	60.254	48.874	EPSD	COSMIC;GDSC;CCLE	59.390	Loss
AGC_PKN_PKN1_ST	P00533	EGFR	Q16512	PKN1	S1162	L1167V	1167	Missense	distal	5	no	60.254	59.995	EPSD	COSMIC	59.390	Down-regulation
AGC_PKN_PKN1_ST	P00533	EGFR	Q16512	PKN1	S1162	D1168Y	1168	Missense	distal	6	no	60.254	59.968	EPSD	COSMIC	59.390	Down-regulation
AGC_PKN_PKN1_ST	P00533	EGFR	Q16512	PKN1	S1162	A1158P	1158	Missense	distal	-4	no	60.254	60.721	EPSD	COSMIC	59.390	Up-regulation
AGC_PKN_PKN1_ST	P00533	EGFR	Q16512	PKN1	S1166	P1170S	1170	Missense	distal	4	no	58.373	61.816	EPSD	COSMIC	59.390	Gain
AGC_PKN_PKN1_ST	P00533	EGFR	Q16512	PKN1	S1166	D1168Y	1168	Missense	proximal	2	no	58.373	60.455	EPSD	COSMIC	59.390	Gain
AGC_PKN_PKN1_ST	Q9UKV0	HDAC9	Q16512	PKN1	T141	E142D	142	Missense	proximal	1	no	55.429	61.559	EPSD	COSMIC	59.390	Gain
AGC_PKN_PKN1_ST	Q9UKV0	HDAC9	Q16512	PKN1	T183	D186Y	186	Missense	distal	3	no	60.745	60.189	EPSD	COSMIC	59.390	Down-regulation
AGC_PKN_PKN1_ST	Q9UKV0	HDAC9	Q16512	PKN1	T183	Q187H	187	Missense	distal	4	no	60.745	49.077	EPSD	COSMIC	59.390	Loss
AGC_PKN_PKN1_ST	Q9UKV0	HDAC9	Q16512	PKN1	T183	T178M	178	Missense	distal	-5	no	60.745	61.026	EPSD	COSMIC	59.390	Up-regulation
AGC_PKN_PKN1_ST	Q9UKV0	HDAC9	Q16512	PKN1	T183	H181Y	181	Missense	proximal	-2	no	60.745	52.129	EPSD	COSMIC	59.390	Loss
AGC_PKN_PKN1_ST	Q9UKV0	HDAC9	Q16512	PKN1	T183	H181N	181	Missense	proximal	-2	no	60.745	59.981	EPSD	COSMIC	59.390	Down-regulation
AGC_PKN_PKN1_ST	Q9UKV0	HDAC9	Q16512	PKN1	T183	H182N	182	Missense	proximal	-1	no	60.745	61.539	EPSD	COSMIC	59.390	Up-regulation
AGC_PKN_PKN1_ST	Q9UKV0	HDAC9	Q16512	PKN1	T183	A180T	180	Missense	distal	-3	no	60.745	66.925	EPSD	COSMIC	59.390	Up-regulation
AGC_PKN_PKN1_ST	Q9UKV0	HDAC9	Q16512	PKN1	T183	A179T	179	Missense	distal	-4	no	60.745	60.697	EPSD	COSMIC	59.390	Down-regulation
AGC_PKN_PKN1_ST	Q9UKV0	HDAC9	Q16512	PKN1	T218	R216Q	216	Missense	proximal	-2	no	60.448	55.092	EPSD	COSMIC	59.390	Loss
AGC_PKN_PKN1_ST	Q9UKV0	HDAC9	Q16512	PKN1	T218	P222L	222	Missense	distal	4	no	60.448	62.192	EPSD	COSMIC	59.390	Up-regulation
AGC_PKN_PKN1_ST	Q9UKV0	HDAC9	Q16512	PKN1	T218	L215F	215	Missense	distal	-3	no	60.448	60.887	EPSD	COSMIC	59.390	Up-regulation
AGC_PKN_PKN1_ST	Q9UKV0	HDAC9	Q16512	PKN1	T218	P222H	222	Missense	distal	4	no	60.448	55.808	EPSD	COSMIC	59.390	Loss
AGC_PKN_PKN1_ST	Q9UKV0	HDAC9	Q16512	PKN1	T218	S220F	220	Missense	proximal	2	no	60.448	61.178	EPSD	COSMIC	59.390	Up-regulation
AGC_PKN_PKN1_ST	Q9UKV0	HDAC9	Q16512	PKN1	S240	P241T	241	Missense	proximal	1	no	73.557	66.276	EPSD	COSMIC	59.390	Down-regulation
AGC_PKN_PKN1_ST	Q9UKV0	HDAC9	Q16512	PKN1	S240	S240I	240	Missense	central	0	yes	73.557	0.000	EPSD	COSMIC	59.390	Loss
AGC_PKN_PKN1_ST	Q9UKV0	HDAC9	Q16512	PKN1	S240	D247Y	247	Missense	distal	7	no	73.557	73.146	EPSD	COSMIC	59.390	Down-regulation
AGC_PKN_PKN1_ST	Q9UKV0	HDAC9	Q16512	PKN1	S240	R238K	238	Missense	proximal	-2	no	73.557	64.153	EPSD	COSMIC	59.390	Down-regulation
AGC_PKN_PKN1_ST	Q9UKV0	HDAC9	Q16512	PKN1	S240	S240R	240	Missense	central	0	yes	73.557	0.000	EPSD	COSMIC	59.390	Loss
AGC_PKN_PKN1_ST	Q9UKV0	HDAC9	Q16512	PKN1	S240	R245Q	245	Missense	distal	5	no	73.557	72.953	EPSD	COSMIC	59.390	Down-regulation
AGC_PKN_PKN1_ST	Q9UKV0	HDAC9	Q16512	PKN1	S253	V251A	251	Missense	proximal	-2	no	96.882	102.646	PhosphoSitePlus	COSMIC	59.390	Up-regulation
AGC_PKN_PKN1_ST	Q9UKV0	HDAC9	Q16512	PKN1	S253	S253L	253	Missense	central	0	yes	96.882	0.000	PhosphoSitePlus	COSMIC	59.390	Loss
AGC_PKN_PKN1_ST	Q9UKV0	HDAC9	Q16512	PKN1	S253	D247Y	247	Missense	distal	-6	no	96.882	96.733	PhosphoSitePlus	COSMIC	59.390	Down-regulation
AGC_PKN_PKN1_ST	Q9UKV0	HDAC9	Q16512	PKN1	S253	T252I	252	Missense	proximal	-1	no	96.882	96.684	PhosphoSitePlus	COSMIC	59.390	Down-regulation
AGC_PKN_PKN1_ST	Q9UKV0	HDAC9	Q16512	PKN1	S253	M258I	258	Missense	distal	5	no	96.882	96.576	PhosphoSitePlus	COSMIC	59.390	Down-regulation
AGC_PKN_PKN1_ST	Q9UKV0	HDAC9	Q16512	PKN1	S253	R257Q	257	Missense	distal	4	no	96.882	95.562	PhosphoSitePlus	COSMIC	59.390	Down-regulation
AGC_PKN_PKN1_ST	Q9UKV0	HDAC9	Q16512	PKN1	S253	G248E	248	Missense	distal	-5	no	96.882	94.564	PhosphoSitePlus	COSMIC	59.390	Down-regulation
AGC_PKN_PKN1_ST	Q9UKV0	HDAC9	Q16512	PKN1	S253	F254L	254	Missense	proximal	1	no	96.882	86.973	PhosphoSitePlus	COSMIC	59.390	Down-regulation
AGC_PKN_PKN1_ST	Q9UKV0	HDAC9	Q16512	PKN1	S253	E260K	260	Missense	distal	7	no	96.882	96.336	PhosphoSitePlus	COSMIC	59.390	Down-regulation
AGC_PKN_PKN1_ST	Q9UKV0	HDAC9	Q16512	PKN1	S451	L454W	454	Missense	distal	3	no	61.079	60.542	EPSD	COSMIC	59.390	Down-regulation
AGC_PKN_PKN1_ST	Q9UKV0	HDAC9	Q16512	PKN1	S451	P445L	445	Missense	distal	-6	no	61.079	60.595	EPSD	COSMIC	59.390	Down-regulation
AGC_PKN_PKN1_ST	Q9UKV0	HDAC9	Q16512	PKN1	S451	N447D	447	Missense	distal	-4	no	61.079	58.730	EPSD	COSMIC	59.390	Loss
AGC_PKN_PKN1_ST	Q9UKV0	HDAC9	Q16512	PKN1	S451	P453H	453	Missense	proximal	2	no	61.079	59.953	EPSD	COSMIC	59.390	Down-regulation
AGC_PKN_PKN1_ST	Q9UKV0	HDAC9	Q16512	PKN1	S451	R448L	448	Missense	distal	-3	no	61.079	43.805	EPSD	COSMIC	59.390	Loss
AGC_PKN_PKN1_ST	Q9UKV0	HDAC9	Q16512	PKN1	S451	R448Q	448	Missense	distal	-3	no	61.079	51.397	EPSD	COSMIC	59.390	Loss
AGC_PKN_PKN1_ST	Q9UKV0	HDAC9	Q16512	PKN1	S451	P453L	453	Missense	proximal	2	no	61.079	61.568	EPSD	COSMIC	59.390	Up-regulation
AGC_PKN_PKN1_ST	Q9UKV0	HDAC9	Q16512	PKN1	S451	T458R	458	Missense	distal	7	no	61.079	61.444	EPSD	COSMIC	59.390	Up-regulation
AGC_PKN_PKN1_ST	Q9UKV0	HDAC9	Q16512	PKN1	S451	P445T	445	Missense	distal	-6	no	61.079	60.512	EPSD	COSMIC	59.390	Down-regulation
AGC_PKN_PKN1_ST	Q9UKV0	HDAC9	Q16512	PKN1	S451	P455H	455	Missense	distal	4	no	61.079	56.439	EPSD	COSMIC	59.390	Loss
AGC_PKN_PKN1_ST	Q9UKV0	HDAC9	Q16512	PKN1	S451	R444G	444	Missense	distal	-7	no	61.079	61.091	EPSD	COSMIC	59.390	Up-regulation
AGC_PKN_PKN1_ST	Q9UKV0	HDAC9	Q16512	PKN1	S451	Q456H	456	Missense	distal	5	no	61.079	60.979	EPSD	COSMIC	59.390	Down-regulation
AGC_PKN_PKN1_ST	Q9UKV0	HDAC9	Q16512	PKN1	S457	L462P	462	Missense	distal	5	no	66.684	66.446	EPSD	COSMIC	59.390	Down-regulation
AGC_PKN_PKN1_ST	Q9UKV0	HDAC9	Q16512	PKN1	S457	L454W	454	Missense	distal	-3	no	66.684	42.525	EPSD	COSMIC	59.390	Loss
AGC_PKN_PKN1_ST	Q9UKV0	HDAC9	Q16512	PKN1	S457	P453H	453	Missense	distal	-4	no	66.684	67.252	EPSD	COSMIC	59.390	Up-regulation
AGC_PKN_PKN1_ST	Q9UKV0	HDAC9	Q16512	PKN1	S457	P453L	453	Missense	distal	-4	no	66.684	66.643	EPSD	COSMIC	59.390	Down-regulation
AGC_PKN_PKN1_ST	Q9UKV0	HDAC9	Q16512	PKN1	S457	T458R	458	Missense	proximal	1	no	66.684	77.672	EPSD	COSMIC	59.390	Up-regulation
AGC_PKN_PKN1_ST	Q9UKV0	HDAC9	Q16512	PKN1	S457	P455H	455	Missense	proximal	-2	no	66.684	72.983	EPSD	COSMIC	59.390	Up-regulation
AGC_PKN_PKN1_ST	Q9UKV0	HDAC9	Q16512	PKN1	S457	Q456H	456	Missense	proximal	-1	no	66.684	64.056	EPSD	COSMIC	59.390	Down-regulation
AGC_PKN_PKN1_ST	Q9UKV0	HDAC9	Q16512	PKN1	S554	E550K	550	Missense	distal	-4	no	56.102	59.803	EPSD	COSMIC	59.390	Gain
AGC_PKN_PKN1_ST	Q9UKV0	HDAC9	Q16512	PKN1	S611	A614V	614	Missense	distal	3	no	64.406	64.046	EPSD	COSMIC;CCLE	59.390	Down-regulation
AGC_PKN_PKN1_ST	Q9UKV0	HDAC9	Q16512	PKN1	S611	V606L	606	Missense	distal	-5	no	64.406	65.552	EPSD	COSMIC	59.390	Up-regulation
AGC_PKN_PKN1_ST	Q9UKV0	HDAC9	Q16512	PKN1	S611	V606I	606	Missense	distal	-5	no	64.406	63.825	EPSD	COSMIC;CCLE	59.390	Down-regulation
AGC_PKN_PKN1_ST	Q9UKV0	HDAC9	Q16512	PKN1	S611	V606A	606	Missense	distal	-5	no	64.406	64.522	EPSD	COSMIC	59.390	Up-regulation
AGC_PKN_PKN1_ST	Q9UKV0	HDAC9	Q16512	PKN1	S663	I661T	661	Missense	proximal	-2	no	60.191	61.312	EPSD	COSMIC	59.390	Up-regulation
AGC_PKN_PKN1_ST	Q9UKV0	HDAC9	Q16512	PKN1	S663	Q669H	669	Missense	distal	6	no	60.191	60.254	EPSD	COSMIC	59.390	Up-regulation
AGC_PKN_PKN1_ST	Q9UKV0	HDAC9	Q16512	PKN1	S663	H657N	657	Missense	distal	-6	no	60.191	61.543	EPSD	COSMIC	59.390	Up-regulation
AGC_PKN_PKN1_ST	Q9UKV0	HDAC9	Q16512	PKN1	S663	I664T	664	Missense	proximal	1	no	60.191	57.430	EPSD	COSMIC	59.390	Loss
AGC_PKN_PKN1_ST	Q9UQL6	HDAC5	Q16512	PKN1	T70	Q74K	74	Missense	distal	4	no	59.610	50.705	EPSD	COSMIC	59.390	Loss
AGC_PKN_PKN1_ST	Q9UQL6	HDAC5	Q16512	PKN1	T70	R72W	72	Missense	proximal	2	no	59.610	57.472	EPSD	COSMIC	59.390	Loss
AGC_PKN_PKN1_ST	Q9UQL6	HDAC5	Q16512	PKN1	S220	L221F	221	Missense	proximal	1	no	54.721	64.630	EPSD	COSMIC	59.390	Gain
AGC_PKN_PKN1_ST	Q9UQL6	HDAC5	Q16512	PKN1	S220	S224R	224	Missense	distal	4	no	54.721	59.628	EPSD	COSMIC	59.390	Gain
AGC_PKN_PKN1_ST	Q9UQL6	HDAC5	Q16512	PKN1	T257	R255C	255	Missense	proximal	-2	no	67.274	48.054	EPSD	COSMIC	59.390	Loss
AGC_PKN_PKN1_ST	Q9UQL6	HDAC5	Q16512	PKN1	S279	R284C	284	Missense	distal	5	no	66.221	64.958	EPSD	COSMIC	59.390	Down-regulation
AGC_PKN_PKN1_ST	Q9UQL6	HDAC5	Q16512	PKN1	S279	S279N	279	Missense	central	0	yes	66.221	0.000	EPSD	COSMIC	59.390	Loss
AGC_PKN_PKN1_ST	Q9UQL6	HDAC5	Q16512	PKN1	S279	R284S	284	Missense	distal	5	no	66.221	65.793	EPSD	COSMIC	59.390	Down-regulation
AGC_PKN_PKN1_ST	Q9UQL6	HDAC5	Q16512	PKN1	S291	T292I	292	Missense	proximal	1	no	56.842	59.603	EPSD	COSMIC	59.390	Gain
AGC_PKN_PKN1_ST	Q9UQL6	HDAC5	Q16512	PKN1	T292	G287E	287	Missense	distal	-5	no	91.265	88.947	PhosphoSitePlus	COSMIC	59.390	Down-regulation
AGC_PKN_PKN1_ST	Q9UQL6	HDAC5	Q16512	PKN1	T292	T292I	292	Missense	central	0	yes	91.265	0.000	PhosphoSitePlus	COSMIC	59.390	Loss
AGC_PKN_PKN1_ST	Q9UQL6	HDAC5	Q16512	PKN1	S458	R455Q	455	Missense	distal	-3	no	64.529	54.847	EPSD	COSMIC	59.390	Loss
AGC_PKN_PKN1_ST	Q9UQL6	HDAC5	Q16512	PKN1	S458	R455W	455	Missense	distal	-3	no	64.529	23.097	EPSD	COSMIC	59.390	Loss
AGC_PKN_PKN1_ST	Q9UQL6	HDAC5	Q16512	PKN1	S458	L460I	460	Missense	proximal	2	no	64.529	64.266	EPSD	COSMIC	59.390	Down-regulation
AGC_PKN_PKN1_ST	Q9UQL6	HDAC5	Q16512	PKN1	T479	R476H	476	Missense	distal	-3	no	62.623	41.561	EPSD	COSMIC	59.390	Loss
AGC_PKN_PKN1_ST	Q9UQL6	HDAC5	Q16512	PKN1	T479	T473M	473	Missense	distal	-6	no	62.623	62.844	EPSD	COSMIC	59.390	Up-regulation
AGC_PKN_PKN1_ST	Q9UQL6	HDAC5	Q16512	PKN1	T479	G474C	474	Missense	distal	-5	no	62.623	60.929	EPSD	COSMIC	59.390	Down-regulation
AGC_PKN_PKN1_ST	Q9UQL6	HDAC5	Q16512	PKN1	T479	R476C	476	Missense	distal	-3	no	62.623	-14.240	EPSD	COSMIC	59.390	Loss
AGC_PKN_PKN1_ST	Q9UQL6	HDAC5	Q16512	PKN1	T479	T483M	483	Missense	distal	4	no	62.623	62.348	EPSD	COSMIC	59.390	Down-regulation
AGC_PKN_PKN1_ST	Q9UQL6	HDAC5	Q16512	PKN1	T479	A478V	478	Missense	proximal	-1	no	62.623	62.811	EPSD	COSMIC;CCLE	59.390	Up-regulation
AGC_PKN_PKN1_ST	Q9UQL6	HDAC5	Q16512	PKN1	T479	R482W	482	Missense	distal	3	no	62.623	61.924	EPSD	COSMIC	59.390	Down-regulation
AGC_PKN_PKN1_ST	Q9UQL6	HDAC5	Q16512	PKN1	T650	A649T	649	Missense	proximal	-1	no	68.199	70.831	EPSD	COSMIC	59.390	Up-regulation
AGC_PKN_PKN1_ST	Q9UQL6	HDAC5	Q16512	PKN1	S661	R658L	658	Missense	distal	-3	no	63.687	46.413	EPSD	COSMIC	59.390	Loss
AGC_PKN_PKN1_ST	Q9UQL6	HDAC5	Q16512	PKN1	S661	R658H	658	Missense	distal	-3	no	63.687	42.625	EPSD	COSMIC	59.390	Loss
AGC_PKN_PKN1_ST	Q9UQL6	HDAC5	Q16512	PKN1	S661	T659S	659	Missense	proximal	-2	no	63.687	68.994	EPSD	COSMIC	59.390	Up-regulation
AGC_PKN_PKN1_ST	Q9UQL6	HDAC5	Q16512	PKN1	S713	R717H	717	Missense	distal	4	no	59.671	46.682	EPSD	COSMIC	59.390	Loss
AGC_PKN_PKN1_ST	Q9UQL6	HDAC5	Q16512	PKN1	S713	R710Q	710	Missense	distal	-3	no	59.671	49.989	EPSD	COSMIC	59.390	Loss
AGC_PKN_PKN1_ST	Q9UQL6	HDAC5	Q16512	PKN1	S713	Q719H	719	Missense	distal	6	no	59.671	59.734	EPSD	COSMIC	59.390	Up-regulation
AGC_PKN_PKN1_ST	Q9UQL6	HDAC5	Q16512	PKN1	S713	S713G	713	Missense	central	0	yes	59.671	0.000	EPSD	COSMIC	59.390	Loss
AGC_PKN_PKN1_ST	O15553	MEFV	Q16512	PKN1	S242	G236E	236	Missense	distal	-6	no	83.262	81.560	EPSD;PhosphoSitePlus	COSMIC	59.390	Down-regulation
AGC_PKN_PKN1_ST	O15553	MEFV	Q16512	PKN1	S347	G351A	351	Missense	distal	4	no	53.851	65.213	EPSD	COSMIC	59.390	Gain
AGC_PKN_PKN1_ST	P30622	CLIP1	Q16512	PKN1	S180	T182M	182	Missense	proximal	2	no	58.830	59.703	EPSD	COSMIC	59.390	Gain
AGC_PKN_PKN1_ST	P30622	CLIP1	Q16512	PKN1	S180	P179T	179	Missense	proximal	-1	no	58.830	60.013	EPSD	COSMIC	59.390	Gain
AGC_PKN_PKN1_ST	P30622	CLIP1	Q16512	PKN1	S186	T182M	182	Missense	distal	-4	no	60.580	61.114	EPSD	COSMIC	59.390	Up-regulation
AGC_PKN_PKN1_ST	P30622	CLIP1	Q16512	PKN1	S186	P179T	179	Missense	distal	-7	no	60.580	60.652	EPSD	COSMIC	59.390	Up-regulation
AGC_PKN_PKN1_ST	P30622	CLIP1	Q16512	PKN1	S186	S193G	193	Missense	distal	7	no	60.580	60.397	EPSD	COSMIC	59.390	Down-regulation
AGC_PKN_PKN1_ST	P30622	CLIP1	Q16512	PKN1	S193	I196V	196	Missense	distal	3	no	59.377	59.687	EPSD	COSMIC	59.390	Gain
AGC_PKN_PKN1_ST	P30622	CLIP1	Q16512	PKN1	S306	V299L	299	Missense	distal	-7	no	63.911	63.875	EPSD	COSMIC	59.390	Down-regulation
AGC_PKN_PKN1_ST	P30622	CLIP1	Q16512	PKN1	S306	T303M	303	Missense	distal	-3	no	63.911	20.602	EPSD	COSMIC	59.390	Loss
AGC_PKN_PKN1_ST	P30622	CLIP1	Q16512	PKN1	S306	V299M	299	Missense	distal	-7	no	63.911	63.970	EPSD	COSMIC	59.390	Up-regulation
AGC_PKN_PKN1_ST	P30622	CLIP1	Q16512	PKN1	S306	A301V	301	Missense	distal	-5	no	63.911	63.795	EPSD	COSMIC	59.390	Down-regulation
AGC_PKN_PKN1_ST	P30622	CLIP1	Q16512	PKN1	S306	A301T	301	Missense	distal	-5	no	63.911	63.885	EPSD	COSMIC;CCLE	59.390	Down-regulation
AGC_PKN_PKN1_ST	P30622	CLIP1	Q16512	PKN1	S328	P330L	330	Missense	proximal	2	no	62.490	62.979	EPSD	COSMIC	59.390	Up-regulation
AGC_PKN_PKN1_ST	P30622	CLIP1	Q16512	PKN1	S331	P330L	330	Missense	proximal	-1	no	62.196	60.564	EPSD	COSMIC	59.390	Down-regulation
AGC_PKN_PKN1_ST	P30622	CLIP1	Q16512	PKN1	S784	K781I	781	Missense	distal	-3	no	63.519	27.610	EPSD	COSMIC	59.390	Loss
AGC_PKN_PKN1_ST	P30622	CLIP1	Q16512	PKN1	S784	L779F	779	Missense	distal	-5	no	63.519	63.325	EPSD	COSMIC	59.390	Down-regulation
AGC_PKN_PKN1_ST	P30622	CLIP1	Q16512	PKN1	T1036	E1042K	1042	Missense	distal	6	no	68.162	68.868	EPSD	COSMIC	59.390	Up-regulation
AGC_PKN_PKN1_ST	P30622	CLIP1	Q16512	PKN1	T1036	R1031G	1031	Missense	distal	-5	no	68.162	68.066	EPSD	COSMIC	59.390	Down-regulation
AGC_PKN_PKN1_ST	P30622	CLIP1	Q16512	PKN1	T1036	E1030D	1030	Missense	distal	-6	no	68.162	69.038	EPSD	COSMIC	59.390	Up-regulation
AGC_PKN_PKN1_ST	P30622	CLIP1	Q16512	PKN1	S1304	Q1300E	1300	Missense	distal	-4	no	63.033	56.028	EPSD	COSMIC	59.390	Loss
AGC_PKN_PKN1_ST	P30622	CLIP1	Q16512	PKN1	T1308	E1314K	1314	Missense	distal	6	no	58.692	59.398	EPSD	COSMIC	59.390	Gain
AGC_PKN_PKN1_ST	Q16512	PKN1	Q16512	PKN1	T64	R60W	60	Missense	distal	-4	no	81.694	77.842	EPSD	COSMIC	59.390	Down-regulation
AGC_PKN_PKN1_ST	Q16512	PKN1	Q16512	PKN1	T64	N58K	58	Missense	distal	-6	no	81.694	81.395	EPSD	COSMIC	59.390	Down-regulation
AGC_PKN_PKN1_ST	Q16512	PKN1	Q16512	PKN1	S80	S81L	81	Missense	proximal	1	no	58.211	64.913	EPSD	COSMIC	59.390	Gain
AGC_PKN_PKN1_ST	Q16512	PKN1	Q16512	PKN1	S81	S81L	81	Missense	central	0	yes	72.999	0.000	EPSD	COSMIC	59.390	Loss
AGC_PKN_PKN1_ST	Q16512	PKN1	Q16512	PKN1	S126	A122V	122	Missense	distal	-4	no	68.591	67.830	EPSD	COSMIC	59.390	Down-regulation
AGC_PKN_PKN1_ST	Q16512	PKN1	Q16512	PKN1	S126	R127H	127	Missense	proximal	1	no	68.591	60.008	EPSD	COSMIC	59.390	Down-regulation
AGC_PKN_PKN1_ST	Q16512	PKN1	Q16512	PKN1	S126	L125M	125	Missense	proximal	-1	no	68.591	70.034	EPSD	COSMIC;CCLE	59.390	Up-regulation
AGC_PKN_PKN1_ST	Q16512	PKN1	Q16512	PKN1	S126	G130D	130	Missense	distal	4	no	68.591	67.575	EPSD	COSMIC	59.390	Down-regulation
AGC_PKN_PKN1_ST	Q16512	PKN1	Q16512	PKN1	S126	L131M	131	Missense	distal	5	no	68.591	68.358	EPSD	COSMIC;GDSC	59.390	Down-regulation
AGC_PKN_PKN1_ST	Q16512	PKN1	Q16512	PKN1	S240	R237C	237	Missense	distal	-3	no	62.490	-14.373	EPSD	COSMIC;CCLE	59.390	Loss
AGC_PKN_PKN1_ST	Q16512	PKN1	Q16512	PKN1	S374	R378Q	378	Missense	distal	4	no	88.259	86.939	EPSD	COSMIC	59.390	Down-regulation
AGC_PKN_PKN1_ST	Q16512	PKN1	Q16512	PKN1	T529	T527M	527	Missense	proximal	-2	no	67.940	64.114	EPSD	COSMIC	59.390	Down-regulation
AGC_PKN_PKN1_ST	Q16512	PKN1	Q16512	PKN1	T545	S540F	540	Missense	distal	-5	no	71.987	72.642	EPSD	COSMIC;CCLE	59.390	Up-regulation
AGC_PKN_PKN1_ST	Q16512	PKN1	Q16512	PKN1	T545	T545M	545	Missense	central	0	yes	71.987	0.000	EPSD	COSMIC	59.390	Loss
AGC_PKN_PKN1_ST	Q16512	PKN1	Q16512	PKN1	S575	S576N	576	Missense	proximal	1	no	56.002	63.456	EPSD	COSMIC	59.390	Gain
AGC_PKN_PKN1_ST	Q16512	PKN1	Q16512	PKN1	T596	A600T	600	Missense	distal	4	no	74.034	72.563	EPSD	COSMIC	59.390	Down-regulation
AGC_PKN_PKN1_ST	Q16512	PKN1	Q16512	PKN1	T596	Q594H	594	Missense	proximal	-2	no	74.034	74.767	EPSD	COSMIC	59.390	Up-regulation
AGC_PKN_PKN1_ST	Q16512	PKN1	Q16512	PKN1	T774	G767R	767	Missense	distal	-7	no	95.095	95.083	PhosphoSitePlus	COSMIC	59.390	Down-regulation
AGC_PKN_PKN1_ST	Q16512	PKN1	Q16512	PKN1	T899	T899A	899	Missense	central	0	yes	64.664	0.000	EPSD	COSMIC	59.390	Loss
AGC_PKN_PKN1_ST	Q16512	PKN1	Q16512	PKN1	T899	D900N	900	Missense	proximal	1	no	64.664	63.356	EPSD	COSMIC	59.390	Down-regulation
Atypical_PIKK_SMG1_SMG1_ST	Q92900	UPF1	Q96Q15	SMG1	S42	P48S	48	Missense	distal	6	no	2.743	2.766	EPSD	COSMIC;GDSC;CCLE	1.372	Up-regulation
Atypical_PIKK_SMG1_SMG1_ST	Q92900	UPF1	Q96Q15	SMG1	T44	P48S	48	Missense	distal	4	no	3.393	3.369	EPSD	COSMIC;GDSC;CCLE	1.372	Down-regulation
Atypical_PIKK_SMG1_SMG1_ST	Q92900	UPF1	Q96Q15	SMG1	S215	S218C	218	Missense	distal	3	no	3.393	3.099	EPSD	COSMIC	1.372	Down-regulation
Atypical_PIKK_SMG1_SMG1_ST	Q92900	UPF1	Q96Q15	SMG1	S485	D481N	481	Missense	distal	-4	no	2.995	2.996	EPSD	COSMIC	1.372	Up-regulation
Atypical_PIKK_SMG1_SMG1_ST	Q92900	UPF1	Q96Q15	SMG1	S485	V490M	490	Missense	distal	5	no	2.995	2.993	EPSD	COSMIC	1.372	Down-regulation
Atypical_PIKK_SMG1_SMG1_ST	Q92900	UPF1	Q96Q15	SMG1	S599	E603K	603	Missense	distal	4	no	1.949	1.807	EPSD	COSMIC;GDSC;CCLE	1.372	Down-regulation
Atypical_PIKK_SMG1_SMG1_ST	Q92900	UPF1	Q96Q15	SMG1	S599	E594G	594	Missense	distal	-5	no	1.949	1.967	EPSD	COSMIC	1.372	Up-regulation
Atypical_PIKK_SMG1_SMG1_ST	Q92900	UPF1	Q96Q15	SMG1	S599	D602G	602	Missense	distal	3	no	1.949	1.666	EPSD	COSMIC	1.372	Down-regulation
Atypical_PIKK_SMG1_SMG1_ST	Q92900	UPF1	Q96Q15	SMG1	S692	A687P	687	Missense	distal	-5	no	3.881	3.895	EPSD	COSMIC	1.372	Up-regulation
Atypical_PIKK_SMG1_SMG1_ST	Q92900	UPF1	Q96Q15	SMG1	S1084	P1086Q	1086	Missense	proximal	2	no	6.300	6.328	EPSD;PhosphoSitePlus	COSMIC	1.372	Up-regulation
Atypical_PIKK_SMG1_SMG1_ST	Q92900	UPF1	Q96Q15	SMG1	S1084	S1089F	1089	Missense	distal	5	no	6.300	6.307	EPSD;PhosphoSitePlus	COSMIC	1.372	Up-regulation
Atypical_PIKK_SMG1_SMG1_ST	Q92900	UPF1	Q96Q15	SMG1	S1089	P1086Q	1086	Missense	distal	-3	no	5.994	5.460	EPSD;PhosphoSitePlus	COSMIC	1.372	Down-regulation
Atypical_PIKK_SMG1_SMG1_ST	Q92900	UPF1	Q96Q15	SMG1	S1089	L1094I	1094	Missense	distal	5	no	5.994	5.978	EPSD;PhosphoSitePlus	COSMIC;CCLE	1.372	Down-regulation
Atypical_PIKK_SMG1_SMG1_ST	Q92900	UPF1	Q96Q15	SMG1	S1089	S1089F	1089	Missense	central	0	yes	5.994	0.000	EPSD;PhosphoSitePlus	COSMIC	1.372	Loss
Atypical_PIKK_SMG1_SMG1_ST	Q92900	UPF1	Q96Q15	SMG1	S1100	L1094I	1094	Missense	distal	-6	no	2.980	2.981	EPSD	COSMIC;CCLE	1.372	Up-regulation
Atypical_PIKK_SMG1_SMG1_ST	Q92900	UPF1	Q96Q15	SMG1	S1100	V1104M	1104	Missense	distal	4	no	2.980	3.083	EPSD	COSMIC	1.372	Up-regulation
Atypical_PIKK_SMG1_SMG1_ST	Q92900	UPF1	Q96Q15	SMG1	S1107	Q1113H	1113	Missense	distal	6	no	6.017	5.934	EPSD;PhosphoSitePlus	COSMIC	1.372	Down-regulation
Atypical_PIKK_SMG1_SMG1_ST	Q92900	UPF1	Q96Q15	SMG1	S1107	V1104M	1104	Missense	distal	-3	no	6.017	5.960	EPSD;PhosphoSitePlus	COSMIC	1.372	Down-regulation
Atypical_PIKK_SMG1_SMG1_ST	P04637	TP53	Q96Q15	SMG1	S15	E11Q	11	Missense	distal	-4	no	5.075	5.065	PhosphoSitePlus	COSMIC;GDSC;CCLE	1.372	Down-regulation
Atypical_PIKK_SMG1_SMG1_ST	P04637	TP53	Q96Q15	SMG1	S15	S20L	20	Missense	distal	5	no	5.075	5.088	PhosphoSitePlus	COSMIC	1.372	Up-regulation
Atypical_PIKK_SMG1_SMG1_ST	P04637	TP53	Q96Q15	SMG1	S15	Q16L	16	Missense	proximal	1	no	5.075	1.828	PhosphoSitePlus	COSMIC;GDSC;CCLE	1.372	Down-regulation
Atypical_PIKK_SMG1_SMG1_ST	P04637	TP53	Q96Q15	SMG1	S15	P13S	13	Missense	proximal	-2	no	5.075	5.056	PhosphoSitePlus	COSMIC	1.372	Down-regulation
Atypical_PIKK_SMG1_SMG1_ST	P04637	TP53	Q96Q15	SMG1	S15	E17K	17	Missense	proximal	2	no	5.075	5.063	PhosphoSitePlus	COSMIC	1.372	Down-regulation
Atypical_PIKK_SMG1_SMG1_ST	P04637	TP53	Q96Q15	SMG1	S15	V10I	10	Missense	distal	-5	no	5.075	5.058	PhosphoSitePlus	COSMIC	1.372	Down-regulation
Atypical_PIKK_SMG1_SMG1_ST	P04637	TP53	Q96Q15	SMG1	S15	P8L	8	Missense	distal	-7	no	5.075	5.116	PhosphoSitePlus	COSMIC	1.372	Up-regulation
Atypical_PIKK_SMG1_SMG1_ST	P04637	TP53	Q96Q15	SMG1	S15	P8S	8	Missense	distal	-7	no	5.075	5.092	PhosphoSitePlus	COSMIC	1.372	Up-regulation
Atypical_PIKK_SMG1_SMG1_ST	P04637	TP53	Q96Q15	SMG1	S15	P13L	13	Missense	proximal	-2	no	5.075	5.059	PhosphoSitePlus	COSMIC	1.372	Down-regulation
Atypical_PIKK_SMG1_SMG1_ST	P04637	TP53	Q96Q15	SMG1	S15	V10G	10	Missense	distal	-5	no	5.075	5.070	PhosphoSitePlus	COSMIC	1.372	Down-regulation
Atypical_PIKK_SMG1_SMG1_ST	P04637	TP53	Q96Q15	SMG1	S15	T18A	18	Missense	distal	3	no	5.075	4.936	PhosphoSitePlus	COSMIC	1.372	Down-regulation
Atypical_PIKK_SMG1_SMG1_ST	P04637	TP53	Q96Q15	SMG1	S15	F19S	19	Missense	distal	4	no	5.075	5.008	PhosphoSitePlus	COSMIC	1.372	Down-regulation
Atypical_PIKK_SMG1_SMG1_ST	P04637	TP53	Q96Q15	SMG1	S15	E17V	17	Missense	proximal	2	no	5.075	5.072	PhosphoSitePlus	COSMIC	1.372	Down-regulation
Atypical_PIKK_SMG1_SMG1_ST	P04637	TP53	Q96Q15	SMG1	S15	S9G	9	Missense	distal	-6	no	5.075	5.079	PhosphoSitePlus	COSMIC	1.372	Up-regulation
Atypical_PIKK_SMG1_SMG1_ST	P04637	TP53	Q96Q15	SMG1	S15	T18I	18	Missense	distal	3	no	5.075	4.922	PhosphoSitePlus	COSMIC	1.372	Down-regulation
Atypical_PIKK_SMG1_SMG1_ST	P04637	TP53	Q96Q15	SMG1	S15	T18K	18	Missense	distal	3	no	5.075	4.887	PhosphoSitePlus	COSMIC	1.372	Down-regulation
Atypical_PIKK_SMG1_SMG1_ST	P04637	TP53	Q96Q15	SMG1	S15	T18R	18	Missense	distal	3	no	5.075	4.908	PhosphoSitePlus	COSMIC	1.372	Down-regulation
Atypical_PIKK_SMG1_SMG1_ST	P04637	TP53	Q96Q15	SMG1	S15	S15I	15	Missense	central	0	yes	5.075	0.000	PhosphoSitePlus	COSMIC	1.372	Loss
Atypical_PIKK_SMG1_SMG1_ST	P04637	TP53	Q96Q15	SMG1	S33	M40I	40	Missense	distal	7	no	1.652	1.639	EPSD	COSMIC	1.372	Down-regulation
Atypical_PIKK_SMG1_SMG1_ST	P04637	TP53	Q96Q15	SMG1	S33	V31I	31	Missense	proximal	-2	no	1.652	1.650	EPSD	COSMIC;GDSC;CCLE	1.372	Down-regulation
Atypical_PIKK_SMG1_SMG1_ST	P04637	TP53	Q96Q15	SMG1	S33	P36L	36	Missense	distal	3	no	1.652	1.473	EPSD	COSMIC;GDSC;CCLE	1.372	Down-regulation
Atypical_PIKK_SMG1_SMG1_ST	P04637	TP53	Q96Q15	SMG1	S33	L35F	35	Missense	proximal	2	no	1.652	1.661	EPSD	COSMIC	1.372	Up-regulation
Atypical_PIKK_SMG1_SMG1_ST	P04637	TP53	Q96Q15	SMG1	S33	Q38L	38	Missense	distal	5	no	1.652	1.658	EPSD	COSMIC	1.372	Up-regulation
Atypical_PIKK_SMG1_SMG1_ST	P04637	TP53	Q96Q15	SMG1	S33	S37T	37	Missense	distal	4	no	1.652	1.686	EPSD	COSMIC	1.372	Up-regulation
Atypical_PIKK_SMG1_SMG1_ST	P04637	TP53	Q96Q15	SMG1	S33	L26P	26	Missense	distal	-7	no	1.652	1.611	EPSD	COSMIC	1.372	Down-regulation
Atypical_PIKK_SMG1_SMG1_ST	P04637	TP53	Q96Q15	SMG1	S33	P36S	36	Missense	distal	3	no	1.652	2.133	EPSD	COSMIC;GDSC;CCLE	1.372	Up-regulation
Atypical_PIKK_SMG1_SMG1_ST	P04637	TP53	Q96Q15	SMG1	S33	A39V	39	Missense	distal	6	no	1.652	1.638	EPSD	COSMIC	1.372	Down-regulation
Atypical_PIKK_SMG1_SMG1_ST	P04637	TP53	Q96Q15	SMG1	S33	A39S	39	Missense	distal	6	no	1.652	1.655	EPSD	COSMIC	1.372	Up-regulation
Atypical_PIKK_SMG1_SMG1_ST	P04637	TP53	Q96Q15	SMG1	S33	N30K	30	Missense	distal	-3	no	1.652	1.705	EPSD	COSMIC	1.372	Up-regulation
Atypical_PIKK_SMG1_SMG1_ST	P04637	TP53	Q96Q15	SMG1	S33	A39T	39	Missense	distal	6	no	1.652	1.649	EPSD	COSMIC	1.372	Down-regulation
Atypical_PIKK_SMG1_SMG1_ST	P04637	TP53	Q96Q15	SMG1	S33	P27T	27	Missense	distal	-6	no	1.652	1.643	EPSD	COSMIC	1.372	Down-regulation
Atypical_PIKK_SMG1_SMG1_ST	P04637	TP53	Q96Q15	SMG1	S33	P36R	36	Missense	distal	3	no	1.652	1.853	EPSD	COSMIC	1.372	Up-regulation
Atypical_PIKK_SMG1_SMG1_ST	P04637	TP53	Q96Q15	SMG1	S33	L35R	35	Missense	proximal	2	no	1.652	1.648	EPSD	COSMIC	1.372	Down-regulation
Atypical_PIKK_SMG1_SMG1_ST	P04637	TP53	Q96Q15	SMG1	S33	L35H	35	Missense	proximal	2	no	1.652	1.651	EPSD	COSMIC	1.372	Down-regulation
Atypical_PIKK_SMG1_SMG1_ST	P04637	TP53	Q96Q15	SMG1	S33	L35P	35	Missense	proximal	2	no	1.652	1.637	EPSD	COSMIC	1.372	Down-regulation
Atypical_PIKK_SMG1_SMG1_ST	P04637	TP53	Q96Q15	SMG1	S33	L35I	35	Missense	proximal	2	no	1.652	1.650	EPSD	COSMIC	1.372	Down-regulation
Atypical_PIKK_SMG1_SMG1_ST	P04637	TP53	Q96Q15	SMG1	S33	L35V	35	Missense	proximal	2	no	1.652	1.653	EPSD	COSMIC	1.372	Up-regulation
Atypical_PIKK_SMG1_SMG1_ST	P04637	TP53	Q96Q15	SMG1	S37	M40I	40	Missense	distal	3	no	2.919	2.877	EPSD	COSMIC	1.372	Down-regulation
Atypical_PIKK_SMG1_SMG1_ST	P04637	TP53	Q96Q15	SMG1	S37	V31I	31	Missense	distal	-6	no	2.919	2.909	EPSD	COSMIC;GDSC;CCLE	1.372	Down-regulation
Atypical_PIKK_SMG1_SMG1_ST	P04637	TP53	Q96Q15	SMG1	S37	P36L	36	Missense	proximal	-1	no	2.919	4.124	EPSD	COSMIC;GDSC;CCLE	1.372	Up-regulation
Atypical_PIKK_SMG1_SMG1_ST	P04637	TP53	Q96Q15	SMG1	S37	D41N	41	Missense	distal	4	no	2.919	2.890	EPSD	COSMIC	1.372	Down-regulation
Atypical_PIKK_SMG1_SMG1_ST	P04637	TP53	Q96Q15	SMG1	S37	L35F	35	Missense	proximal	-2	no	2.919	2.924	EPSD	COSMIC	1.372	Up-regulation
Atypical_PIKK_SMG1_SMG1_ST	P04637	TP53	Q96Q15	SMG1	S37	Q38L	38	Missense	proximal	1	no	2.919	-0.327	EPSD	COSMIC	1.372	Loss
Atypical_PIKK_SMG1_SMG1_ST	P04637	TP53	Q96Q15	SMG1	S37	M44I	44	Missense	distal	7	no	2.919	2.906	EPSD	COSMIC	1.372	Down-regulation
Atypical_PIKK_SMG1_SMG1_ST	P04637	TP53	Q96Q15	SMG1	S37	P36S	36	Missense	proximal	-1	no	2.919	2.650	EPSD	COSMIC;GDSC;CCLE	1.372	Down-regulation
Atypical_PIKK_SMG1_SMG1_ST	P04637	TP53	Q96Q15	SMG1	S37	A39V	39	Missense	proximal	2	no	2.919	2.922	EPSD	COSMIC	1.372	Up-regulation
Atypical_PIKK_SMG1_SMG1_ST	P04637	TP53	Q96Q15	SMG1	S37	A39S	39	Missense	proximal	2	no	2.919	2.924	EPSD	COSMIC	1.372	Up-regulation
Atypical_PIKK_SMG1_SMG1_ST	P04637	TP53	Q96Q15	SMG1	S37	D42Y	42	Missense	distal	5	no	2.919	2.950	EPSD	COSMIC	1.372	Up-regulation
Atypical_PIKK_SMG1_SMG1_ST	P04637	TP53	Q96Q15	SMG1	S37	M44R	44	Missense	distal	7	no	2.919	2.916	EPSD	COSMIC	1.372	Down-regulation
Atypical_PIKK_SMG1_SMG1_ST	P04637	TP53	Q96Q15	SMG1	S37	M44V	44	Missense	distal	7	no	2.919	2.948	EPSD	COSMIC	1.372	Up-regulation
Atypical_PIKK_SMG1_SMG1_ST	P04637	TP53	Q96Q15	SMG1	S37	N30K	30	Missense	distal	-7	no	2.919	2.910	EPSD	COSMIC	1.372	Down-regulation
Atypical_PIKK_SMG1_SMG1_ST	P04637	TP53	Q96Q15	SMG1	S37	M44T	44	Missense	distal	7	no	2.919	2.951	EPSD	COSMIC	1.372	Up-regulation
Atypical_PIKK_SMG1_SMG1_ST	P04637	TP53	Q96Q15	SMG1	S37	L43F	43	Missense	distal	6	no	2.919	2.939	EPSD	COSMIC	1.372	Up-regulation
Atypical_PIKK_SMG1_SMG1_ST	P04637	TP53	Q96Q15	SMG1	S37	D41H	41	Missense	distal	4	no	2.919	2.886	EPSD	COSMIC	1.372	Down-regulation
Atypical_PIKK_SMG1_SMG1_ST	P04637	TP53	Q96Q15	SMG1	S37	P36R	36	Missense	proximal	-1	no	2.919	3.064	EPSD	COSMIC	1.372	Up-regulation
Atypical_PIKK_SMG1_SMG1_ST	P04637	TP53	Q96Q15	SMG1	S37	L35R	35	Missense	proximal	-2	no	2.919	2.923	EPSD	COSMIC	1.372	Up-regulation
Atypical_PIKK_SMG1_SMG1_ST	P04637	TP53	Q96Q15	SMG1	S37	L35H	35	Missense	proximal	-2	no	2.919	2.922	EPSD	COSMIC	1.372	Up-regulation
Atypical_PIKK_SMG1_SMG1_ST	P04637	TP53	Q96Q15	SMG1	S37	L35P	35	Missense	proximal	-2	no	2.919	2.935	EPSD	COSMIC	1.372	Up-regulation
Atypical_PIKK_SMG1_SMG1_ST	P04637	TP53	Q96Q15	SMG1	S37	L35I	35	Missense	proximal	-2	no	2.919	2.923	EPSD	COSMIC	1.372	Up-regulation
Atypical_PIKK_SMG1_SMG1_ST	P04637	TP53	Q96Q15	SMG1	S37	L35V	35	Missense	proximal	-2	no	2.919	2.926	EPSD	COSMIC	1.372	Up-regulation
Atypical_PIKK_SMG1_SMG1_ST	P04637	TP53	Q96Q15	SMG1	S37	D41E	41	Missense	distal	4	no	2.919	3.009	EPSD	COSMIC	1.372	Up-regulation
Atypical_PIKK_SMG1_SMG1_ST	P04637	TP53	Q96Q15	SMG1	S46	P47S	47	Missense	proximal	1	no	0.846	1.497	EPSD	COSMIC	1.372	Gain
Atypical_PIKK_SMG1_SMG1_ST	P04637	TP53	Q96Q15	SMG1	T55	F54L	54	Missense	proximal	-1	no	1.006	2.417	EPSD	COSMIC	1.372	Gain
Atypical_PIKK_SMG1_SMG1_ST	P04637	TP53	Q96Q15	SMG1	T55	P58S	58	Missense	distal	3	no	1.006	1.487	EPSD	COSMIC	1.372	Gain
Atypical_PIKK_SMG1_SMG1_ST	P04637	TP53	Q96Q15	SMG1	T55	P58T	58	Missense	distal	3	no	1.006	1.372	EPSD	COSMIC	1.372	Gain
Atypical_PIKK_SMG1_SMG1_ST	P04637	TP53	Q96Q15	SMG1	S99	S99F	99	Missense	central	0	yes	3.102	0.000	EPSD	COSMIC	1.372	Loss
Atypical_PIKK_SMG1_SMG1_ST	P04637	TP53	Q96Q15	SMG1	S99	S96F	96	Missense	distal	-3	no	3.102	3.294	EPSD	COSMIC	1.372	Up-regulation
Atypical_PIKK_SMG1_SMG1_ST	P04637	TP53	Q96Q15	SMG1	S99	P98S	98	Missense	proximal	-1	no	3.102	2.833	EPSD	COSMIC;CCLE	1.372	Down-regulation
Atypical_PIKK_SMG1_SMG1_ST	P04637	TP53	Q96Q15	SMG1	S99	T102I	102	Missense	distal	3	no	3.102	2.949	EPSD	COSMIC	1.372	Down-regulation
Atypical_PIKK_SMG1_SMG1_ST	P04637	TP53	Q96Q15	SMG1	S99	S94P	94	Missense	distal	-5	no	3.102	3.115	EPSD	COSMIC	1.372	Up-regulation
Atypical_PIKK_SMG1_SMG1_ST	P04637	TP53	Q96Q15	SMG1	S99	K101R	101	Missense	proximal	2	no	3.102	3.105	EPSD	COSMIC	1.372	Up-regulation
Atypical_PIKK_SMG1_SMG1_ST	P04637	TP53	Q96Q15	SMG1	S99	S94T	94	Missense	distal	-5	no	3.102	3.081	EPSD	COSMIC	1.372	Down-regulation
Atypical_PIKK_SMG1_SMG1_ST	P04637	TP53	Q96Q15	SMG1	S99	P98L	98	Missense	proximal	-1	no	3.102	4.307	EPSD	COSMIC;GDSC;CCLE	1.372	Up-regulation
Atypical_PIKK_SMG1_SMG1_ST	P04637	TP53	Q96Q15	SMG1	S99	S95F	95	Missense	distal	-4	no	3.102	3.104	EPSD	COSMIC;CCLE	1.372	Up-regulation
Atypical_PIKK_SMG1_SMG1_ST	P04637	TP53	Q96Q15	SMG1	S99	S96C	96	Missense	distal	-3	no	3.102	3.264	EPSD	COSMIC	1.372	Up-regulation
Atypical_PIKK_SMG1_SMG1_ST	P04637	TP53	Q96Q15	SMG1	S99	S106I	106	Missense	distal	7	no	3.102	3.073	EPSD	COSMIC	1.372	Down-regulation
Atypical_PIKK_SMG1_SMG1_ST	P04637	TP53	Q96Q15	SMG1	S99	P98F	98	Missense	proximal	-1	no	3.102	2.895	EPSD	COSMIC	1.372	Down-regulation
Atypical_PIKK_SMG1_SMG1_ST	P04637	TP53	Q96Q15	SMG1	S99	T102P	102	Missense	distal	3	no	3.102	2.736	EPSD	COSMIC	1.372	Down-regulation
Atypical_PIKK_SMG1_SMG1_ST	P04637	TP53	Q96Q15	SMG1	S99	S94L	94	Missense	distal	-5	no	3.102	3.100	EPSD	COSMIC	1.372	Down-regulation
Atypical_PIKK_SMG1_SMG1_ST	P04637	TP53	Q96Q15	SMG1	S99	S96P	96	Missense	distal	-3	no	3.102	3.574	EPSD	COSMIC	1.372	Up-regulation
Atypical_PIKK_SMG1_SMG1_ST	P04637	TP53	Q96Q15	SMG1	S99	P98T	98	Missense	proximal	-1	no	3.102	2.983	EPSD	COSMIC	1.372	Down-regulation
Atypical_PIKK_SMG1_SMG1_ST	P04637	TP53	Q96Q15	SMG1	S99	S96Y	96	Missense	distal	-3	no	3.102	3.174	EPSD	COSMIC	1.372	Up-regulation
Atypical_PIKK_SMG1_SMG1_ST	P04637	TP53	Q96Q15	SMG1	S99	S99P	99	Missense	central	0	yes	3.102	0.000	EPSD	COSMIC	1.372	Loss
Atypical_PIKK_SMG1_SMG1_ST	P04637	TP53	Q96Q15	SMG1	S99	V97I	97	Missense	proximal	-2	no	3.102	3.099	EPSD	COSMIC	1.372	Down-regulation
Atypical_PIKK_SMG1_SMG1_ST	P04637	TP53	Q96Q15	SMG1	S99	Q104H	104	Missense	distal	5	no	3.102	3.096	EPSD	COSMIC	1.372	Down-regulation
Atypical_PIKK_SMG1_SMG1_ST	P04637	TP53	Q96Q15	SMG1	S99	L93M	93	Missense	distal	-6	no	3.102	3.106	EPSD	COSMIC	1.372	Up-regulation
Atypical_PIKK_SMG1_SMG1_ST	P04637	TP53	Q96Q15	SMG1	S99	K101N	101	Missense	proximal	2	no	3.102	3.110	EPSD	COSMIC	1.372	Up-regulation
Atypical_PIKK_SMG1_SMG1_ST	P04637	TP53	Q96Q15	SMG1	S99	V97A	97	Missense	proximal	-2	no	3.102	3.098	EPSD	COSMIC	1.372	Down-regulation
Atypical_PIKK_SMG1_SMG1_ST	P04637	TP53	Q96Q15	SMG1	S99	P92A	92	Missense	distal	-7	no	3.102	3.109	EPSD	COSMIC	1.372	Up-regulation
Atypical_PIKK_SMG1_SMG1_ST	P04637	TP53	Q96Q15	SMG1	S99	Q104L	104	Missense	distal	5	no	3.102	3.108	EPSD	COSMIC	1.372	Up-regulation
Atypical_PIKK_SMG1_SMG1_ST	P04637	TP53	Q96Q15	SMG1	S99	P92L	92	Missense	distal	-7	no	3.102	3.144	EPSD	COSMIC	1.372	Up-regulation
Atypical_PIKK_SMG1_SMG1_ST	P04637	TP53	Q96Q15	SMG1	S99	L93P	93	Missense	distal	-6	no	3.102	3.113	EPSD	COSMIC	1.372	Up-regulation
Atypical_PIKK_SMG1_SMG1_ST	P04637	TP53	Q96Q15	SMG1	S99	L93F	93	Missense	distal	-6	no	3.102	3.115	EPSD	COSMIC	1.372	Up-regulation
Atypical_PIKK_SMG1_SMG1_ST	P04637	TP53	Q96Q15	SMG1	S99	L93H	93	Missense	distal	-6	no	3.102	3.107	EPSD	COSMIC	1.372	Up-regulation
Atypical_PIKK_SMG1_SMG1_ST	P04637	TP53	Q96Q15	SMG1	S99	S95Y	95	Missense	distal	-4	no	3.102	3.103	EPSD	COSMIC	1.372	Up-regulation
Atypical_PIKK_SMG1_SMG1_ST	P04637	TP53	Q96Q15	SMG1	S106	Y107Q	107	Missense	proximal	1	no	0.738	3.670	EPSD	COSMIC	1.372	Gain
STE_STE11_ASK_MAP3K6_ST	P45983	MAPK8	O95382	MAP3K6	T19	D17N	17	Missense	proximal	-2	no	4.888	4.795	EPSD	COSMIC	1.891	Down-regulation
STE_STE11_ASK_MAP3K6_ST	P45983	MAPK8	O95382	MAP3K6	T178	G177R	177	Missense	proximal	-1	no	1.978	1.949	EPSD	COSMIC	1.891	Down-regulation
STE_STE11_ASK_MAP3K6_ST	P45983	MAPK8	O95382	MAP3K6	T178	G177K	177	Missense	proximal	-1	no	1.978	1.985	EPSD	COSMIC	1.891	Up-regulation
STE_STE11_ASK_MAP3K6_ST	P45983	MAPK8	O95382	MAP3K6	T178	G171S	171	Missense	distal	-7	no	1.978	1.904	EPSD	COSMIC	1.891	Down-regulation
STE_STE11_ASK_MAP3K6_ST	P45983	MAPK8	O95382	MAP3K6	T178	T183A	183	Missense	distal	5	no	1.978	1.497	EPSD	COSMIC	1.891	Loss
STE_STE11_ASK_MAP3K6_ST	P45983	MAPK8	O95382	MAP3K6	T183	G177R	177	Missense	distal	-6	no	15.332	15.395	PhosphoSitePlus;EPSD	COSMIC	1.891	Up-regulation
STE_STE11_ASK_MAP3K6_ST	P45983	MAPK8	O95382	MAP3K6	T183	R189G	189	Missense	distal	6	no	15.332	14.516	PhosphoSitePlus;EPSD	COSMIC	1.891	Down-regulation
STE_STE11_ASK_MAP3K6_ST	P45983	MAPK8	O95382	MAP3K6	T183	G177K	177	Missense	distal	-6	no	15.332	15.376	PhosphoSitePlus;EPSD	COSMIC	1.891	Up-regulation
STE_STE11_ASK_MAP3K6_ST	P45983	MAPK8	O95382	MAP3K6	T183	T183A	183	Missense	central	0	yes	15.332	0.000	PhosphoSitePlus;EPSD	COSMIC	1.891	Loss
STE_STE11_ASK_MAP3K6_ST	P45983	MAPK8	O95382	MAP3K6	T188	R189G	189	Missense	proximal	1	no	1.928	1.834	EPSD	COSMIC	1.891	Loss
STE_STE11_ASK_MAP3K6_ST	P45983	MAPK8	O95382	MAP3K6	T188	T183A	183	Missense	distal	-5	no	1.928	0.227	EPSD	COSMIC	1.891	Loss
STE_STE11_ASK_MAP3K6_ST	P45983	MAPK8	O95382	MAP3K6	T367	G370A	370	Missense	distal	3	no	2.498	2.409	EPSD	COSMIC	1.891	Down-regulation
STE_STE11_ASK_MAP3K6_ST	P45983	MAPK8	O95382	MAP3K6	T367	L363F	363	Missense	distal	-4	no	2.498	2.483	EPSD	COSMIC	1.891	Down-regulation
STE_STE11_ASK_MAP3K6_ST	P45983	MAPK8	O95382	MAP3K6	T367	R373L	373	Missense	distal	6	no	2.498	1.827	EPSD	COSMIC	1.891	Loss
STE_STE11_ASK_MAP3K6_ST	O95382	MAP3K6	O95382	MAP3K6	T806	T808S	808	Missense	proximal	2	no	16.036	14.974	PhosphoSitePlus	COSMIC	1.891	Down-regulation
STE_STE11_ASK_MAP3K6_ST	O95382	MAP3K6	O95382	MAP3K6	T806	L811V	811	Missense	distal	5	no	16.036	15.869	PhosphoSitePlus	COSMIC	1.891	Down-regulation
STE_STE11_ASK_MAP3K6_ST	O95382	MAP3K6	O95382	MAP3K6	S938	S942F	942	Missense	distal	4	no	2.245	2.318	EPSD	COSMIC	1.891	Up-regulation
STE_STE11_ASK_MAP3K6_ST	O95382	MAP3K6	O95382	MAP3K6	T944	S942F	942	Missense	proximal	-2	no	3.665	3.621	EPSD	COSMIC	1.891	Down-regulation
STE_STE11_ASK_MAP3K6_ST	O95382	MAP3K6	O95382	MAP3K6	T944	P948S	948	Missense	distal	4	no	3.665	3.573	EPSD	COSMIC	1.891	Down-regulation
STE_STE11_ASK_MAP3K6_ST	O95382	MAP3K6	O95382	MAP3K6	T944	P951S	951	Missense	distal	7	no	3.665	3.717	EPSD	COSMIC	1.891	Up-regulation
STE_STE11_ASK_MAP3K6_ST	O95382	MAP3K6	O95382	MAP3K6	T944	P948R	948	Missense	distal	4	no	3.665	3.662	EPSD	COSMIC	1.891	Down-regulation
STE_STE11_ASK_MAP3K6_ST	Q16539	MAPK14	O95382	MAP3K6	T175	A172V	172	Missense	distal	-3	no	2.601	2.584	EPSD	COSMIC	1.891	Down-regulation
STE_STE11_ASK_MAP3K6_ST	Q16539	MAPK14	O95382	MAP3K6	T180	T185I	185	Missense	distal	5	no	15.416	14.910	PhosphoSitePlus;EPSD	COSMIC	1.891	Down-regulation
STE_STE11_ASK_MAP3K6_ST	Q16539	MAPK14	O95382	MAP3K6	T185	T185I	185	Missense	central	0	yes	2.339	0.000	EPSD	COSMIC	1.891	Loss
CAMK_DAPK_DAPK_DAPK1_ST	P53355	DAPK1	P53355	DAPK1	S57	R63Q	63	Missense	distal	6	no	10.150	10.242	EPSD	COSMIC	8.849	Up-regulation
CAMK_DAPK_DAPK_DAPK1_ST	P53355	DAPK1	P53355	DAPK1	S57	G55D	55	Missense	proximal	-2	no	10.150	10.095	EPSD	COSMIC	8.849	Down-regulation
CAMK_DAPK_DAPK_DAPK1_ST	P53355	DAPK1	P53355	DAPK1	S308	V309I	309	Missense	proximal	1	no	14.981	15.473	PhosphoSitePlus	COSMIC	8.849	Up-regulation
CAMK_DAPK_DAPK_DAPK1_ST	P53355	DAPK1	P53355	DAPK1	S308	R302W	302	Missense	distal	-6	no	14.981	14.089	PhosphoSitePlus	COSMIC	8.849	Down-regulation
CAMK_DAPK_DAPK_DAPK1_ST	P53355	DAPK1	P53355	DAPK1	S308	R310H	310	Missense	proximal	2	no	14.981	14.939	PhosphoSitePlus	COSMIC	8.849	Down-regulation
CAMK_DAPK_DAPK_DAPK1_ST	P53355	DAPK1	P53355	DAPK1	S313	V309I	309	Missense	distal	-4	no	15.405	15.502	EPSD	COSMIC	8.849	Up-regulation
CAMK_DAPK_DAPK_DAPK1_ST	P53355	DAPK1	P53355	DAPK1	S313	R310H	310	Missense	distal	-3	no	15.405	10.774	EPSD	COSMIC	8.849	Down-regulation
CAMK_DAPK_DAPK_DAPK1_ST	P53355	DAPK1	P53355	DAPK1	S635	L629F	629	Missense	distal	-6	no	11.113	10.669	EPSD	COSMIC	8.849	Down-regulation
CAMK_DAPK_DAPK_DAPK1_ST	P53355	DAPK1	P53355	DAPK1	S728	R730K	730	Missense	proximal	2	no	9.630	9.555	EPSD	COSMIC	8.849	Down-regulation
CAMK_DAPK_DAPK_DAPK1_ST	P53355	DAPK1	P53355	DAPK1	S728	P733L	733	Missense	distal	5	no	9.630	8.923	EPSD	COSMIC	8.849	Down-regulation
CAMK_DAPK_DAPK_DAPK1_ST	P53355	DAPK1	P53355	DAPK1	S762	P767L	767	Missense	distal	5	no	9.106	8.398	EPSD	COSMIC	8.849	Loss
CAMK_DAPK_DAPK_DAPK1_ST	P53355	DAPK1	P53355	DAPK1	S762	M764V	764	Missense	proximal	2	no	9.106	9.469	EPSD	COSMIC	8.849	Up-regulation
CAMK_DAPK_DAPK_DAPK1_ST	P53355	DAPK1	P53355	DAPK1	S762	F765S	765	Missense	distal	3	no	9.106	7.679	EPSD	COSMIC	8.849	Loss
CAMK_DAPK_DAPK_DAPK1_ST	P53355	DAPK1	P53355	DAPK1	S762	R761C	761	Missense	proximal	-1	no	9.106	8.090	EPSD	COSMIC	8.849	Loss
CAMK_DAPK_DAPK_DAPK1_ST	O95786	DDX58	P53355	DAPK1	S654	F655C	655	Missense	proximal	1	no	16.697	17.209	PhosphoSitePlus;EPSD	COSMIC	8.849	Up-regulation
CAMK_DAPK_DAPK_DAPK1_ST	O95786	DDX58	P53355	DAPK1	T667	Q669H	669	Missense	proximal	2	no	16.192	15.699	EPSD;PhosphoSitePlus	COSMIC	8.849	Down-regulation
CAMK_DAPK_DAPK_DAPK1_ST	O95786	DDX58	P53355	DAPK1	T667	G665D	665	Missense	proximal	-2	no	16.192	16.137	EPSD;PhosphoSitePlus	COSMIC	8.849	Down-regulation
CAMK_DAPK_DAPK_DAPK1_ST	O95786	DDX58	P53355	DAPK1	T667	R664C	664	Missense	distal	-3	no	16.192	11.365	EPSD;PhosphoSitePlus	COSMIC;CCLE	8.849	Down-regulation
CAMK_DAPK_DAPK_DAPK1_ST	O95786	DDX58	P53355	DAPK1	T667	T674A	674	Missense	distal	7	no	16.192	16.535	EPSD;PhosphoSitePlus	COSMIC	8.849	Up-regulation
CAMK_DAPK_DAPK_DAPK1_ST	O95786	DDX58	P53355	DAPK1	T671	Q669H	669	Missense	proximal	-2	no	15.563	16.032	EPSD;PhosphoSitePlus	COSMIC	8.849	Up-regulation
CAMK_DAPK_DAPK_DAPK1_ST	O95786	DDX58	P53355	DAPK1	T671	L675I	675	Missense	distal	4	no	15.563	15.519	EPSD;PhosphoSitePlus	COSMIC	8.849	Down-regulation
CAMK_DAPK_DAPK_DAPK1_ST	O95786	DDX58	P53355	DAPK1	T671	G665D	665	Missense	distal	-6	no	15.563	15.908	EPSD;PhosphoSitePlus	COSMIC	8.849	Up-regulation
CAMK_DAPK_DAPK_DAPK1_ST	O95786	DDX58	P53355	DAPK1	T671	R664C	664	Missense	distal	-7	no	15.563	17.485	EPSD;PhosphoSitePlus	COSMIC;CCLE	8.849	Up-regulation
CAMK_DAPK_DAPK_DAPK1_ST	O95786	DDX58	P53355	DAPK1	T671	T674A	674	Missense	distal	3	no	15.563	15.039	EPSD;PhosphoSitePlus	COSMIC	8.849	Down-regulation
CAMK_DAPK_DAPK_DAPK1_ST	O95786	DDX58	P53355	DAPK1	T674	K679T	679	Missense	distal	5	no	14.614	15.071	EPSD;PhosphoSitePlus	COSMIC	8.849	Up-regulation
CAMK_DAPK_DAPK_DAPK1_ST	O95786	DDX58	P53355	DAPK1	T674	I681M	681	Missense	distal	7	no	14.614	14.706	EPSD;PhosphoSitePlus	COSMIC	8.849	Up-regulation
CAMK_DAPK_DAPK_DAPK1_ST	O95786	DDX58	P53355	DAPK1	T674	Q669H	669	Missense	distal	-5	no	14.614	14.444	EPSD;PhosphoSitePlus	COSMIC	8.849	Down-regulation
CAMK_DAPK_DAPK_DAPK1_ST	O95786	DDX58	P53355	DAPK1	T674	L675I	675	Missense	proximal	1	no	14.614	14.741	EPSD;PhosphoSitePlus	COSMIC	8.849	Up-regulation
CAMK_DAPK_DAPK_DAPK1_ST	O95786	DDX58	P53355	DAPK1	T674	T674A	674	Missense	central	0	yes	14.614	0.000	EPSD;PhosphoSitePlus	COSMIC	8.849	Loss
CAMK_DAPK_DAPK_DAPK1_ST	O95786	DDX58	P53355	DAPK1	S764	R767H	767	Missense	distal	3	no	15.563	15.295	EPSD;PhosphoSitePlus	COSMIC;GDSC;CCLE	8.849	Down-regulation
CAMK_DAPK_DAPK_DAPK1_ST	O95786	DDX58	P53355	DAPK1	S764	S764F	764	Missense	central	0	yes	15.563	0.000	EPSD;PhosphoSitePlus	COSMIC	8.849	Loss
CAMK_DAPK_DAPK_DAPK1_ST	O95786	DDX58	P53355	DAPK1	S764	E758K	758	Missense	distal	-6	no	15.563	14.535	EPSD;PhosphoSitePlus	COSMIC	8.849	Down-regulation
CAMK_DAPK_DAPK_DAPK1_ST	O95786	DDX58	P53355	DAPK1	S764	M760I	760	Missense	distal	-4	no	15.563	15.405	EPSD;PhosphoSitePlus	COSMIC	8.849	Down-regulation
CAMK_DAPK_DAPK_DAPK1_ST	O95786	DDX58	P53355	DAPK1	S764	D763Y	763	Missense	proximal	-1	no	15.563	15.609	EPSD;PhosphoSitePlus	COSMIC	8.849	Up-regulation
CAMK_DAPK_DAPK_DAPK1_ST	O95786	DDX58	P53355	DAPK1	T770	R767H	767	Missense	distal	-3	no	15.226	10.596	EPSD;PhosphoSitePlus	COSMIC;GDSC;CCLE	8.849	Down-regulation
CAMK_DAPK_DAPK_DAPK1_ST	O95786	DDX58	P53355	DAPK1	T770	A774E	774	Missense	distal	4	no	15.226	15.045	EPSD;PhosphoSitePlus	COSMIC;CCLE	8.849	Down-regulation
CAMK_DAPK_DAPK_DAPK1_ST	O95786	DDX58	P53355	DAPK1	T770	S764F	764	Missense	distal	-6	no	15.226	13.132	EPSD;PhosphoSitePlus	COSMIC	8.849	Down-regulation
CAMK_DAPK_DAPK_DAPK1_ST	O95786	DDX58	P53355	DAPK1	T770	D763Y	763	Missense	distal	-7	no	15.226	17.372	EPSD;PhosphoSitePlus	COSMIC	8.849	Up-regulation
CAMK_DAPK_DAPK_DAPK1_ST	Q96RR4	CAMKK2	P53355	DAPK1	T145	P144L	144	Missense	proximal	-1	no	9.938	10.831	EPSD	COSMIC	8.849	Up-regulation
CAMK_DAPK_DAPK_DAPK1_ST	Q96RR4	CAMKK2	P53355	DAPK1	T145	P138L	138	Missense	distal	-7	no	9.938	10.258	EPSD	COSMIC	8.849	Up-regulation
CAMK_DAPK_DAPK_DAPK1_ST	Q96RR4	CAMKK2	P53355	DAPK1	T350	L344F	344	Missense	distal	-6	no	9.990	9.546	EPSD	COSMIC	8.849	Down-regulation
CAMK_DAPK_DAPK_DAPK1_ST	Q96RR4	CAMKK2	P53355	DAPK1	S509	R505C	505	Missense	distal	-4	no	9.171	8.834	EPSD	COSMIC	8.849	Loss
CAMK_DAPK_DAPK_DAPK1_ST	Q96RR4	CAMKK2	P53355	DAPK1	S511	R505C	505	Missense	distal	-6	no	15.718	13.378	PhosphoSitePlus	COSMIC	8.849	Down-regulation
CAMK_DAPK_DAPK_DAPK1_ST	Q96RR4	CAMKK2	P53355	DAPK1	S559	V556G	556	Missense	distal	-3	no	9.813	11.832	EPSD	COSMIC	8.849	Up-regulation
CAMK_DAPK_DAPK_DAPK1_ST	Q96RR4	CAMKK2	P53355	DAPK1	S559	V556A	556	Missense	distal	-3	no	9.813	10.517	EPSD	COSMIC	8.849	Up-regulation
CAMK_DAPK_DAPK_DAPK1_ST	Q96RR4	CAMKK2	P53355	DAPK1	S572	A569T	569	Missense	distal	-3	no	5.516	9.591	EPSD	COSMIC	8.849	Gain
CAMK_DAPK_DAPK_DAPK1_ST	Q00613	HSF1	P53355	DAPK1	S136	D129G	129	Missense	distal	-7	no	10.581	10.153	EPSD	COSMIC	8.849	Down-regulation
CAMK_DAPK_DAPK_DAPK1_ST	Q00613	HSF1	P53355	DAPK1	S136	R133S	133	Missense	distal	-3	no	10.581	8.051	EPSD	COSMIC	8.849	Loss
CAMK_DAPK_DAPK_DAPK1_ST	Q00613	HSF1	P53355	DAPK1	S136	V137I	137	Missense	proximal	1	no	10.581	11.072	EPSD	COSMIC	8.849	Up-regulation
CAMK_DAPK_DAPK_DAPK1_ST	Q00613	HSF1	P53355	DAPK1	S136	K139N	139	Missense	distal	3	no	10.581	10.625	EPSD	COSMIC;GDSC;CCLE	8.849	Up-regulation
CAMK_DAPK_DAPK_DAPK1_ST	Q00613	HSF1	P53355	DAPK1	T142	M147I	147	Missense	distal	5	no	9.088	8.551	EPSD	COSMIC	8.849	Loss
CAMK_DAPK_DAPK_DAPK1_ST	Q00613	HSF1	P53355	DAPK1	T142	M147T	147	Missense	distal	5	no	9.088	8.829	EPSD	COSMIC	8.849	Loss
CAMK_DAPK_DAPK_DAPK1_ST	Q00613	HSF1	P53355	DAPK1	T142	V137I	137	Missense	distal	-5	no	9.088	9.075	EPSD	COSMIC	8.849	Down-regulation
CAMK_DAPK_DAPK_DAPK1_ST	Q00613	HSF1	P53355	DAPK1	T142	K139N	139	Missense	distal	-3	no	9.088	7.493	EPSD	COSMIC;GDSC;CCLE	8.849	Loss
CAMK_DAPK_DAPK_DAPK1_ST	Q00613	HSF1	P53355	DAPK1	S216	L211P	211	Missense	distal	-5	no	9.469	9.202	EPSD	COSMIC	8.849	Down-regulation
CAMK_DAPK_DAPK_DAPK1_ST	Q00613	HSF1	P53355	DAPK1	S216	L211R	211	Missense	distal	-5	no	9.469	9.672	EPSD	COSMIC	8.849	Up-regulation
CAMK_DAPK_DAPK_DAPK1_ST	Q00613	HSF1	P53355	DAPK1	S218	L211P	211	Missense	distal	-7	no	10.859	10.539	EPSD	COSMIC	8.849	Down-regulation
CAMK_DAPK_DAPK_DAPK1_ST	Q00613	HSF1	P53355	DAPK1	S218	L211R	211	Missense	distal	-7	no	10.859	8.961	EPSD	COSMIC	8.849	Down-regulation
CAMK_DAPK_DAPK_DAPK1_ST	Q00613	HSF1	P53355	DAPK1	S230	R227Q	227	Missense	distal	-3	no	15.223	11.009	PhosphoSitePlus	COSMIC;GDSC	8.849	Down-regulation
CAMK_DAPK_DAPK_DAPK1_ST	Q00613	HSF1	P53355	DAPK1	S230	G236S	236	Missense	distal	6	no	15.223	13.988	PhosphoSitePlus	COSMIC;CCLE	8.849	Down-regulation
CAMK_DAPK_DAPK_DAPK1_ST	Q00613	HSF1	P53355	DAPK1	S230	S237L	237	Missense	distal	7	no	15.223	14.908	PhosphoSitePlus	COSMIC	8.849	Down-regulation
CAMK_DAPK_DAPK_DAPK1_ST	Q00613	HSF1	P53355	DAPK1	S279	S279F	279	Missense	central	0	yes	10.183	0.000	EPSD	COSMIC	8.849	Loss
CAMK_DAPK_DAPK_DAPK1_ST	Q00613	HSF1	P53355	DAPK1	S279	P280L	280	Missense	proximal	1	no	10.183	9.716	EPSD	COSMIC	8.849	Down-regulation
CAMK_DAPK_DAPK_DAPK1_ST	Q00613	HSF1	P53355	DAPK1	S279	G281S	281	Missense	proximal	2	no	10.183	10.303	EPSD	COSMIC	8.849	Up-regulation
CAMK_DAPK_DAPK_DAPK1_ST	Q00613	HSF1	P53355	DAPK1	S279	S283N	283	Missense	distal	4	no	10.183	9.730	EPSD	COSMIC	8.849	Down-regulation
CAMK_DAPK_DAPK_DAPK1_ST	Q00613	HSF1	P53355	DAPK1	S320	P318T	318	Missense	proximal	-2	no	9.881	11.821	EPSD	COSMIC	8.849	Up-regulation
CAMK_DAPK_DAPK_DAPK1_ST	Q00613	HSF1	P53355	DAPK1	S320	P327Q	327	Missense	distal	7	no	9.881	10.796	EPSD	COSMIC	8.849	Up-regulation
CAMK_DAPK_DAPK_DAPK1_ST	Q00613	HSF1	P53355	DAPK1	S326	L330V	330	Missense	distal	4	no	10.559	11.017	EPSD	COSMIC	8.849	Up-regulation
CAMK_DAPK_DAPK_DAPK1_ST	Q00613	HSF1	P53355	DAPK1	S326	P327Q	327	Missense	proximal	1	no	10.559	9.859	EPSD	COSMIC	8.849	Down-regulation
CAMK_DAPK_DAPK_DAPK1_ST	Q00613	HSF1	P53355	DAPK1	S338	P342T	342	Missense	distal	4	no	9.574	9.743	EPSD	COSMIC	8.849	Up-regulation
CAMK_DAPK_DAPK_DAPK1_ST	Q00613	HSF1	P53355	DAPK1	S338	S344C	344	Missense	distal	6	no	9.574	11.764	EPSD	COSMIC	8.849	Up-regulation
CAMK_DAPK_DAPK_DAPK1_ST	Q00613	HSF1	P53355	DAPK1	S338	R336W	336	Missense	proximal	-2	no	9.574	6.922	EPSD	COSMIC	8.849	Loss
CAMK_DAPK_DAPK_DAPK1_ST	Q00613	HSF1	P53355	DAPK1	S368	P365T	365	Missense	distal	-3	no	5.932	8.995	EPSD	COSMIC	8.849	Gain
CAMK_DAPK_DAPK_DAPK1_ST	Q00613	HSF1	P53355	DAPK1	S438	S434N	434	Missense	distal	-4	no	10.117	10.102	EPSD	COSMIC	8.849	Down-regulation
CAMK_DAPK_DAPK_DAPK1_ST	P40429	RPL13A	P53355	DAPK1	S67	R61Q	61	Missense	distal	-6	no	10.735	10.138	EPSD	COSMIC	8.849	Down-regulation
CAMK_DAPK_DAPK_DAPK1_ST	P40429	RPL13A	P53355	DAPK1	S67	P66L	66	Missense	proximal	-1	no	10.735	11.628	EPSD	COSMIC	8.849	Up-regulation
CAMK_DAPK_DAPK_DAPK1_ST	P40429	RPL13A	P53355	DAPK1	S67	T64I	64	Missense	distal	-3	no	10.735	8.397	EPSD	COSMIC	8.849	Loss
CAMK_DAPK_DAPK_DAPK1_ST	P40429	RPL13A	P53355	DAPK1	S67	T64N	64	Missense	distal	-3	no	10.735	9.665	EPSD	COSMIC	8.849	Down-regulation
CAMK_DAPK_DAPK_DAPK1_ST	O14950	MYL12B	P53355	DAPK1	S20	M25L	25	Missense	distal	5	no	13.300	13.141	PhosphoSitePlus	COSMIC	8.849	Down-regulation
CAMK_DAPK_DAPK_DAPK1_ST	Q14457	BECN1	P53355	DAPK1	T119	L122P	122	Missense	distal	3	no	15.276	15.822	PhosphoSitePlus	COSMIC	8.849	Up-regulation
CAMK_DAPK_DAPK_DAPK1_ST	Q14457	BECN1	P53355	DAPK1	T119	D124E	124	Missense	distal	5	no	15.276	15.030	PhosphoSitePlus	COSMIC	8.849	Down-regulation
CAMK_DAPK_DAPK_DAPK1_ST	Q14457	BECN1	P53355	DAPK1	S234	Q240H	240	Missense	distal	6	no	8.979	8.955	EPSD	COSMIC	8.849	Down-regulation
CAMK_DAPK_DAPK_DAPK1_ST	P04637	TP53	P53355	DAPK1	S46	M40I	40	Missense	distal	-6	no	10.502	8.009	EPSD	COSMIC	8.849	Loss
CAMK_DAPK_DAPK_DAPK1_ST	P04637	TP53	P53355	DAPK1	S46	W53C	53	Missense	distal	7	no	10.502	10.015	EPSD	COSMIC	8.849	Down-regulation
CAMK_DAPK_DAPK_DAPK1_ST	P04637	TP53	P53355	DAPK1	S46	W53G	53	Missense	distal	7	no	10.502	10.094	EPSD	COSMIC	8.849	Down-regulation
CAMK_DAPK_DAPK_DAPK1_ST	P04637	TP53	P53355	DAPK1	S46	S46F	46	Missense	central	0	yes	10.502	0.000	EPSD	COSMIC	8.849	Loss
CAMK_DAPK_DAPK_DAPK1_ST	P04637	TP53	P53355	DAPK1	S46	D49Y	49	Missense	distal	3	no	10.502	9.891	EPSD	COSMIC	8.849	Down-regulation
CAMK_DAPK_DAPK_DAPK1_ST	P04637	TP53	P53355	DAPK1	S46	P47L	47	Missense	proximal	1	no	10.502	10.035	EPSD	COSMIC	8.849	Down-regulation
CAMK_DAPK_DAPK_DAPK1_ST	P04637	TP53	P53355	DAPK1	S46	D49H	49	Missense	distal	3	no	10.502	9.838	EPSD	COSMIC;GDSC;CCLE	8.849	Down-regulation
CAMK_DAPK_DAPK_DAPK1_ST	P04637	TP53	P53355	DAPK1	S46	P47S	47	Missense	proximal	1	no	10.502	9.575	EPSD	COSMIC	8.849	Down-regulation
CAMK_DAPK_DAPK_DAPK1_ST	P04637	TP53	P53355	DAPK1	S46	D41N	41	Missense	distal	-5	no	10.502	10.684	EPSD	COSMIC	8.849	Up-regulation
CAMK_DAPK_DAPK_DAPK1_ST	P04637	TP53	P53355	DAPK1	S46	D48H	48	Missense	proximal	2	no	10.502	10.512	EPSD	COSMIC	8.849	Up-regulation
CAMK_DAPK_DAPK_DAPK1_ST	P04637	TP53	P53355	DAPK1	S46	D49N	49	Missense	distal	3	no	10.502	10.455	EPSD	COSMIC	8.849	Down-regulation
CAMK_DAPK_DAPK_DAPK1_ST	P04637	TP53	P53355	DAPK1	S46	M44I	44	Missense	proximal	-2	no	10.502	8.408	EPSD	COSMIC	8.849	Loss
CAMK_DAPK_DAPK_DAPK1_ST	P04637	TP53	P53355	DAPK1	S46	Q52H	52	Missense	distal	6	no	10.502	10.478	EPSD	COSMIC	8.849	Down-regulation
CAMK_DAPK_DAPK_DAPK1_ST	P04637	TP53	P53355	DAPK1	S46	D49V	49	Missense	distal	3	no	10.502	11.016	EPSD	COSMIC	8.849	Up-regulation
CAMK_DAPK_DAPK_DAPK1_ST	P04637	TP53	P53355	DAPK1	S46	A39V	39	Missense	distal	-7	no	10.502	9.738	EPSD	COSMIC	8.849	Down-regulation
CAMK_DAPK_DAPK_DAPK1_ST	P04637	TP53	P53355	DAPK1	S46	A39S	39	Missense	distal	-7	no	10.502	9.452	EPSD	COSMIC	8.849	Down-regulation
CAMK_DAPK_DAPK_DAPK1_ST	P04637	TP53	P53355	DAPK1	S46	D42Y	42	Missense	distal	-4	no	10.502	10.325	EPSD	COSMIC	8.849	Down-regulation
CAMK_DAPK_DAPK_DAPK1_ST	P04637	TP53	P53355	DAPK1	S46	M44R	44	Missense	proximal	-2	no	10.502	10.536	EPSD	COSMIC	8.849	Up-regulation
CAMK_DAPK_DAPK_DAPK1_ST	P04637	TP53	P53355	DAPK1	S46	S46P	46	Missense	central	0	yes	10.502	0.000	EPSD	COSMIC	8.849	Loss
CAMK_DAPK_DAPK_DAPK1_ST	P04637	TP53	P53355	DAPK1	S46	M44V	44	Missense	proximal	-2	no	10.502	6.221	EPSD	COSMIC	8.849	Loss
CAMK_DAPK_DAPK_DAPK1_ST	P04637	TP53	P53355	DAPK1	S46	L45P	45	Missense	proximal	-1	no	10.502	9.610	EPSD	COSMIC	8.849	Down-regulation
CAMK_DAPK_DAPK_DAPK1_ST	P04637	TP53	P53355	DAPK1	S46	M44T	44	Missense	proximal	-2	no	10.502	7.997	EPSD	COSMIC	8.849	Loss
CAMK_DAPK_DAPK_DAPK1_ST	P04637	TP53	P53355	DAPK1	S46	A39T	39	Missense	distal	-7	no	10.502	10.028	EPSD	COSMIC	8.849	Down-regulation
CAMK_DAPK_DAPK_DAPK1_ST	P04637	TP53	P53355	DAPK1	S46	L43F	43	Missense	distal	-3	no	10.502	9.943	EPSD	COSMIC	8.849	Down-regulation
CAMK_DAPK_DAPK_DAPK1_ST	P04637	TP53	P53355	DAPK1	S46	D41H	41	Missense	distal	-5	no	10.502	10.542	EPSD	COSMIC	8.849	Up-regulation
CAMK_DAPK_DAPK_DAPK1_ST	P04637	TP53	P53355	DAPK1	S46	D49E	49	Missense	distal	3	no	10.502	10.282	EPSD	COSMIC	8.849	Down-regulation
CAMK_DAPK_DAPK_DAPK1_ST	P04637	TP53	P53355	DAPK1	S46	D49G	49	Missense	distal	3	no	10.502	11.384	EPSD	COSMIC	8.849	Up-regulation
CAMK_DAPK_DAPK_DAPK1_ST	P04637	TP53	P53355	DAPK1	S46	D48A	48	Missense	proximal	2	no	10.502	10.362	EPSD	COSMIC	8.849	Down-regulation
CAMK_DAPK_DAPK_DAPK1_ST	P04637	TP53	P53355	DAPK1	S46	D48Y	48	Missense	proximal	2	no	10.502	10.543	EPSD	COSMIC	8.849	Up-regulation
CAMK_DAPK_DAPK_DAPK1_ST	P04637	TP53	P53355	DAPK1	S46	D48E	48	Missense	proximal	2	no	10.502	10.795	EPSD	COSMIC	8.849	Up-regulation
CAMK_DAPK_DAPK_DAPK1_ST	P04637	TP53	P53355	DAPK1	S46	D49I	49	Missense	distal	3	no	10.502	10.453	EPSD	COSMIC	8.849	Down-regulation
CAMK_DAPK_DAPK_DAPK1_ST	P04637	TP53	P53355	DAPK1	S46	D41E	41	Missense	distal	-5	no	10.502	10.580	EPSD	COSMIC	8.849	Up-regulation
CAMK_DAPK_DAPK_DAPK1_ST	P04637	TP53	P53355	DAPK1	S99	V97I	97	Missense	proximal	-2	no	7.164	9.352	EPSD	COSMIC	8.849	Gain
CAMK_DAPK_DAPK_DAPK1_ST	P04637	TP53	P53355	DAPK1	S99	V97A	97	Missense	proximal	-2	no	7.164	8.873	EPSD	COSMIC	8.849	Gain
CAMK_DAPK_DAPK_DAPK1_ST	P04637	TP53	P53355	DAPK1	S215	F212S	212	Missense	distal	-3	no	5.755	8.871	EPSD	COSMIC	8.849	Gain
CAMK_DAPK_DAPK_DAPK1_ST	P04637	TP53	P53355	DAPK1	S269	A276S	276	Missense	distal	7	no	15.697	16.483	EPSD;PhosphoSitePlus	COSMIC	8.849	Up-regulation
CAMK_DAPK_DAPK_DAPK1_ST	P04637	TP53	P53355	DAPK1	S269	G262H	262	Missense	distal	-7	no	15.697	17.541	EPSD;PhosphoSitePlus	COSMIC	8.849	Up-regulation
CAMK_DAPK_DAPK_DAPK1_ST	P04637	TP53	P53355	DAPK1	S269	N263H	263	Missense	distal	-6	no	15.697	13.386	EPSD;PhosphoSitePlus	COSMIC	8.849	Down-regulation
CAMK_DAPK_DAPK_DAPK1_ST	P04637	TP53	P53355	DAPK1	S269	G266A	266	Missense	distal	-3	no	15.697	14.382	EPSD;PhosphoSitePlus	COSMIC	8.849	Down-regulation
CAMK_DAPK_DAPK_DAPK1_ST	P04637	TP53	P53355	DAPK1	S269	S269N	269	Missense	central	0	yes	15.697	0.000	EPSD;PhosphoSitePlus	COSMIC	8.849	Loss
CAMK_DAPK_DAPK_DAPK1_ST	P04637	TP53	P53355	DAPK1	S269	V274I	274	Missense	distal	5	no	15.697	15.028	EPSD;PhosphoSitePlus	COSMIC	8.849	Down-regulation
CAMK_DAPK_DAPK_DAPK1_ST	P04637	TP53	P53355	DAPK1	S269	L265M	265	Missense	distal	-4	no	15.697	15.931	EPSD;PhosphoSitePlus	COSMIC	8.849	Up-regulation
CAMK_DAPK_DAPK_DAPK1_ST	P04637	TP53	P53355	DAPK1	S269	F270Y	270	Missense	proximal	1	no	15.697	15.984	EPSD;PhosphoSitePlus	COSMIC	8.849	Up-regulation
CAMK_DAPK_DAPK_DAPK1_ST	P04637	TP53	P53355	DAPK1	S269	L264V	264	Missense	distal	-5	no	15.697	15.543	EPSD;PhosphoSitePlus	COSMIC	8.849	Down-regulation
CAMK_DAPK_DAPK_DAPK1_ST	P04637	TP53	P53355	DAPK1	S269	S269G	269	Missense	central	0	yes	15.697	0.000	EPSD;PhosphoSitePlus	COSMIC	8.849	Loss
CAMK_DAPK_DAPK_DAPK1_ST	P04637	TP53	P53355	DAPK1	S269	R273Q	273	Missense	distal	4	no	15.697	16.311	EPSD;PhosphoSitePlus	COSMIC	8.849	Up-regulation
CAMK_DAPK_DAPK_DAPK1_ST	P04637	TP53	P53355	DAPK1	S269	N268H	268	Missense	proximal	-1	no	15.697	15.761	EPSD;PhosphoSitePlus	COSMIC	8.849	Up-regulation
CAMK_DAPK_DAPK_DAPK1_ST	P04637	TP53	P53355	DAPK1	S269	G262D	262	Missense	distal	-7	no	15.697	16.124	EPSD;PhosphoSitePlus	COSMIC;GDSC;CCLE	8.849	Up-regulation
CAMK_DAPK_DAPK_DAPK1_ST	P04637	TP53	P53355	DAPK1	S269	N263I	263	Missense	distal	-6	no	15.697	13.068	EPSD;PhosphoSitePlus	COSMIC	8.849	Down-regulation
CAMK_DAPK_DAPK_DAPK1_ST	P04637	TP53	P53355	DAPK1	S269	L264P	264	Missense	distal	-5	no	15.697	15.430	EPSD;PhosphoSitePlus	COSMIC	8.849	Down-regulation
CAMK_DAPK_DAPK_DAPK1_ST	P04637	TP53	P53355	DAPK1	S269	E271P	271	Missense	proximal	2	no	15.697	16.169	EPSD;PhosphoSitePlus	COSMIC	8.849	Up-regulation
CAMK_DAPK_DAPK_DAPK1_ST	P04637	TP53	P53355	DAPK1	S269	L264R	264	Missense	distal	-5	no	15.697	15.900	EPSD;PhosphoSitePlus	COSMIC;GDSC;CCLE	8.849	Up-regulation
CAMK_DAPK_DAPK_DAPK1_ST	P04637	TP53	P53355	DAPK1	S269	R273Y	273	Missense	distal	4	no	15.697	16.032	EPSD;PhosphoSitePlus	COSMIC;CCLE	8.849	Up-regulation
CAMK_DAPK_DAPK_DAPK1_ST	P04637	TP53	P53355	DAPK1	S269	N263D	263	Missense	distal	-6	no	15.697	14.154	EPSD;PhosphoSitePlus	COSMIC	8.849	Down-regulation
CAMK_DAPK_DAPK_DAPK1_ST	P04637	TP53	P53355	DAPK1	S269	A276T	276	Missense	distal	7	no	15.697	15.354	EPSD;PhosphoSitePlus	COSMIC	8.849	Down-regulation
CAMK_DAPK_DAPK_DAPK1_ST	P04637	TP53	P53355	DAPK1	S269	S269C	269	Missense	central	0	yes	15.697	0.000	EPSD;PhosphoSitePlus	COSMIC	8.849	Loss
CAMK_DAPK_DAPK_DAPK1_ST	P04637	TP53	P53355	DAPK1	S269	L264I	264	Missense	distal	-5	no	15.697	15.530	EPSD;PhosphoSitePlus	COSMIC	8.849	Down-regulation
CAMK_DAPK_DAPK_DAPK1_ST	P04637	TP53	P53355	DAPK1	S269	N268K	268	Missense	proximal	-1	no	15.697	15.369	EPSD;PhosphoSitePlus	COSMIC	8.849	Down-regulation
CAMK_DAPK_DAPK_DAPK1_ST	P04637	TP53	P53355	DAPK1	S269	A276F	276	Missense	distal	7	no	15.697	15.601	EPSD;PhosphoSitePlus	COSMIC	8.849	Down-regulation
CAMK_DAPK_DAPK_DAPK1_ST	P04637	TP53	P53355	DAPK1	S269	G266T	266	Missense	distal	-3	no	15.697	18.456	EPSD;PhosphoSitePlus	COSMIC	8.849	Up-regulation
CAMK_DAPK_DAPK_DAPK1_ST	P04637	TP53	P53355	DAPK1	S269	G266K	266	Missense	distal	-3	no	15.697	18.981	EPSD;PhosphoSitePlus	COSMIC	8.849	Up-regulation
CAMK_DAPK_DAPK_DAPK1_ST	P04637	TP53	P53355	DAPK1	S269	E271G	271	Missense	proximal	2	no	15.697	15.380	EPSD;PhosphoSitePlus	COSMIC	8.849	Down-regulation
CAMK_DAPK_DAPK_DAPK1_ST	P04637	TP53	P53355	DAPK1	S269	L264Q	264	Missense	distal	-5	no	15.697	15.744	EPSD;PhosphoSitePlus	COSMIC	8.849	Up-regulation
CAMK_DAPK_DAPK_DAPK1_ST	P04637	TP53	P53355	DAPK1	S269	S269I	269	Missense	central	0	yes	15.697	0.000	EPSD;PhosphoSitePlus	COSMIC	8.849	Loss
CAMK_DAPK_DAPK_DAPK1_ST	P04637	TP53	P53355	DAPK1	S269	S269R	269	Missense	central	0	yes	15.697	0.000	EPSD;PhosphoSitePlus	COSMIC	8.849	Loss
CAMK_DAPK_DAPK_DAPK1_ST	P04637	TP53	P53355	DAPK1	S269	G262R	262	Missense	distal	-7	no	15.697	15.213	EPSD;PhosphoSitePlus	COSMIC	8.849	Down-regulation
CAMK_DAPK_DAPK_DAPK1_ST	P04637	TP53	P53355	DAPK1	S269	N263K	263	Missense	distal	-6	no	15.697	14.471	EPSD;PhosphoSitePlus	COSMIC	8.849	Down-regulation
CAMK_DAPK_DAPK_DAPK1_ST	P04637	TP53	P53355	DAPK1	S269	V272K	272	Missense	distal	3	no	15.697	15.091	EPSD;PhosphoSitePlus	COSMIC	8.849	Down-regulation
CAMK_DAPK_DAPK_DAPK1_ST	P04637	TP53	P53355	DAPK1	S269	N268F	268	Missense	proximal	-1	no	15.697	15.940	EPSD;PhosphoSitePlus	COSMIC	8.849	Up-regulation
CAMK_DAPK_DAPK_DAPK1_ST	P04637	TP53	P53355	DAPK1	S269	L265Q	265	Missense	distal	-4	no	15.697	15.779	EPSD;PhosphoSitePlus	COSMIC	8.849	Up-regulation
CAMK_DAPK_DAPK_DAPK1_ST	P04637	TP53	P53355	DAPK1	S269	N268S	268	Missense	proximal	-1	no	15.697	15.716	EPSD;PhosphoSitePlus	COSMIC	8.849	Up-regulation
CAMK_DAPK_DAPK_DAPK1_ST	P04637	TP53	P53355	DAPK1	S269	G262S	262	Missense	distal	-7	no	15.697	15.679	EPSD;PhosphoSitePlus	COSMIC;GDSC	8.849	Down-regulation
CAMK_DAPK_DAPK_DAPK1_ST	P04637	TP53	P53355	DAPK1	S269	G266S	266	Missense	distal	-3	no	15.697	17.814	EPSD;PhosphoSitePlus	COSMIC	8.849	Up-regulation
CAMK_DAPK_DAPK_DAPK1_ST	P04637	TP53	P53355	DAPK1	T284	D281R	281	Missense	distal	-3	no	6.768	11.045	EPSD	COSMIC	8.849	Gain
CAMK_DAPK_DAPK_DAPK1_ST	P04637	TP53	P53355	DAPK1	T304	P301S	301	Missense	distal	-3	no	6.984	9.405	EPSD	COSMIC	8.849	Gain
CAMK_DAPK_DAPK_DAPK1_ST	P04637	TP53	P53355	DAPK1	T304	G302R	302	Missense	proximal	-2	no	6.984	9.885	EPSD	COSMIC	8.849	Gain
CAMK_DAPK_DAPK_DAPK1_ST	P04637	TP53	P53355	DAPK1	T312	P309S	309	Missense	distal	-3	no	7.745	10.167	EPSD	COSMIC;GDSC;CCLE	8.849	Gain
CAMK_DAPK_DAPK_DAPK1_ST	P04637	TP53	P53355	DAPK1	T312	S315P	315	Missense	distal	3	no	7.745	9.200	EPSD	COSMIC	8.849	Gain
CAMK_DAPK_DAPK_DAPK1_ST	P04637	TP53	P53355	DAPK1	T312	P309R	309	Missense	distal	-3	no	7.745	12.697	EPSD	COSMIC	8.849	Gain
CAMK_DAPK_DAPK_DAPK1_ST	P04637	TP53	P53355	DAPK1	S315	P309S	309	Missense	distal	-6	no	7.290	9.074	EPSD	COSMIC;GDSC;CCLE	8.849	Gain
CAMK_DAPK_DAPK_DAPK1_ST	P04637	TP53	P53355	DAPK1	S315	P309R	309	Missense	distal	-6	no	7.290	9.224	EPSD	COSMIC	8.849	Gain
CAMK_DAPK_DAPK_DAPK1_ST	P04637	TP53	P53355	DAPK1	S367	A364T	364	Missense	distal	-3	no	6.339	10.414	EPSD	COSMIC	8.849	Gain
CAMK_DAPK_DAPK_DAPK1_ST	P04637	TP53	P53355	DAPK1	S371	S367F	367	Missense	distal	-4	no	8.890	8.738	EPSD	COSMIC	8.849	Loss
CAMK_DAPK_DAPK_DAPK1_ST	P04637	TP53	P53355	DAPK1	S371	K370N	370	Missense	proximal	-1	no	8.890	9.218	EPSD	COSMIC	8.849	Up-regulation
CAMK_DAPK_DAPK_DAPK1_ST	P04637	TP53	P53355	DAPK1	S371	A364D	364	Missense	distal	-7	no	8.890	8.285	EPSD	COSMIC	8.849	Loss
CAMK_DAPK_DAPK_DAPK1_ST	P04637	TP53	P53355	DAPK1	S371	H365Y	365	Missense	distal	-6	no	8.890	8.856	EPSD	COSMIC	8.849	Down-regulation
CAMK_DAPK_DAPK_DAPK1_ST	P04637	TP53	P53355	DAPK1	S371	A364T	364	Missense	distal	-7	no	8.890	8.416	EPSD	COSMIC	8.849	Loss
CAMK_DAPK_DAPK_DAPK1_ST	P04637	TP53	P53355	DAPK1	S371	S376T	376	Missense	distal	5	no	8.890	9.500	EPSD	COSMIC	8.849	Up-regulation
CAMK_DAPK_DAPK_DAPK1_ST	P04637	TP53	P53355	DAPK1	S371	S366A	366	Missense	distal	-5	no	8.890	8.642	EPSD	COSMIC	8.849	Loss
CAMK_DAPK_DAPK_DAPK1_ST	P04637	TP53	P53355	DAPK1	S371	T377I	377	Missense	distal	6	no	8.890	8.479	EPSD	COSMIC	8.849	Loss
CAMK_DAPK_DAPK_DAPK1_ST	P04637	TP53	P53355	DAPK1	S371	S378F	378	Missense	distal	7	no	8.890	8.007	EPSD	COSMIC	8.849	Loss
CAMK_DAPK_DAPK_DAPK1_ST	P04637	TP53	P53355	DAPK1	S371	K370Q	370	Missense	proximal	-1	no	8.890	9.267	EPSD	COSMIC	8.849	Up-regulation
CAMK_DAPK_DAPK_DAPK1_ST	P04637	TP53	P53355	DAPK1	S371	K373R	373	Missense	proximal	2	no	8.890	8.964	EPSD	COSMIC	8.849	Up-regulation
CAMK_DAPK_DAPK_DAPK1_ST	P04637	TP53	P53355	DAPK1	S371	S376F	376	Missense	distal	5	no	8.890	8.911	EPSD	COSMIC	8.849	Up-regulation
CAMK_DAPK_DAPK_DAPK1_ST	P04637	TP53	P53355	DAPK1	S371	G374S	374	Missense	distal	3	no	8.890	6.576	EPSD	COSMIC	8.849	Loss
CAMK_DAPK_DAPK_DAPK1_ST	P04637	TP53	P53355	DAPK1	S371	S376A	376	Missense	distal	5	no	8.890	9.640	EPSD	COSMIC	8.849	Up-regulation
CAMK_DAPK_DAPK_DAPK1_ST	P04637	TP53	P53355	DAPK1	S371	S371P	371	Missense	central	0	yes	8.890	0.000	EPSD	COSMIC	8.849	Loss
CAMK_DAPK_DAPK_DAPK1_ST	P04637	TP53	P53355	DAPK1	S376	K370N	370	Missense	distal	-6	no	9.368	10.594	EPSD	COSMIC	8.849	Up-regulation
CAMK_DAPK_DAPK_DAPK1_ST	P04637	TP53	P53355	DAPK1	S376	L383F	383	Missense	distal	7	no	9.368	8.800	EPSD	COSMIC	8.849	Loss
CAMK_DAPK_DAPK_DAPK1_ST	P04637	TP53	P53355	DAPK1	S376	R379H	379	Missense	distal	3	no	9.368	9.101	EPSD	COSMIC	8.849	Down-regulation
CAMK_DAPK_DAPK_DAPK1_ST	P04637	TP53	P53355	DAPK1	S376	H380Y	380	Missense	distal	4	no	9.368	8.381	EPSD	COSMIC	8.849	Loss
CAMK_DAPK_DAPK_DAPK1_ST	P04637	TP53	P53355	DAPK1	S376	T377I	377	Missense	proximal	1	no	9.368	9.392	EPSD	COSMIC	8.849	Up-regulation
CAMK_DAPK_DAPK_DAPK1_ST	P04637	TP53	P53355	DAPK1	S376	S378F	378	Missense	proximal	2	no	9.368	9.155	EPSD	COSMIC	8.849	Down-regulation
CAMK_DAPK_DAPK_DAPK1_ST	P04637	TP53	P53355	DAPK1	S376	K370Q	370	Missense	distal	-6	no	9.368	10.151	EPSD	COSMIC	8.849	Up-regulation
CAMK_DAPK_DAPK_DAPK1_ST	P04637	TP53	P53355	DAPK1	S376	K381N	381	Missense	distal	5	no	9.368	9.745	EPSD	COSMIC	8.849	Up-regulation
CAMK_DAPK_DAPK_DAPK1_ST	P04637	TP53	P53355	DAPK1	S376	R379P	379	Missense	distal	3	no	9.368	9.788	EPSD	COSMIC	8.849	Up-regulation
CAMK_DAPK_DAPK_DAPK1_ST	P04637	TP53	P53355	DAPK1	S376	K373R	373	Missense	distal	-3	no	9.368	10.731	EPSD	COSMIC	8.849	Up-regulation
CAMK_DAPK_DAPK_DAPK1_ST	P04637	TP53	P53355	DAPK1	S376	S376F	376	Missense	central	0	yes	9.368	0.000	EPSD	COSMIC	8.849	Loss
CAMK_DAPK_DAPK_DAPK1_ST	P04637	TP53	P53355	DAPK1	S376	G374S	374	Missense	proximal	-2	no	9.368	10.893	EPSD	COSMIC	8.849	Up-regulation
CAMK_DAPK_DAPK_DAPK1_ST	P04637	TP53	P53355	DAPK1	S376	S376A	376	Missense	central	0	yes	9.368	0.000	EPSD	COSMIC	8.849	Loss
CAMK_DAPK_DAPK_DAPK1_ST	P04637	TP53	P53355	DAPK1	S376	S371P	371	Missense	distal	-5	no	9.368	8.981	EPSD	COSMIC	8.849	Down-regulation
CAMK_DAPK_DAPK_DAPK1_ST	Q13526	PIN1	P53355	DAPK1	S98	E100D	100	Missense	proximal	2	no	9.643	9.350	EPSD	COSMIC	8.849	Down-regulation
CAMK_DAPK_DAPK_DAPK1_ST	P25205	MCM3	P53355	DAPK1	T154	C148R	148	Missense	distal	-6	no	7.716	10.056	EPSD	COSMIC	8.849	Gain
CAMK_DAPK_DAPK_DAPK1_ST	P25205	MCM3	P53355	DAPK1	S160	T163I	163	Missense	distal	3	no	15.355	14.104	PhosphoSitePlus	COSMIC	8.849	Down-regulation
CAMK_DAPK_DAPK_DAPK1_ST	P25205	MCM3	P53355	DAPK1	S373	S374F	374	Missense	proximal	1	no	9.426	9.937	EPSD	COSMIC	8.849	Up-regulation
CAMK_DAPK_DAPK_DAPK1_ST	P25205	MCM3	P53355	DAPK1	S373	T379R	379	Missense	distal	6	no	9.426	7.553	EPSD	COSMIC	8.849	Loss
CAMK_DAPK_DAPK_DAPK1_ST	P25205	MCM3	P53355	DAPK1	S604	A608T	608	Missense	distal	4	no	9.212	9.550	EPSD	COSMIC	8.849	Up-regulation
CAMK_DAPK_DAPK_DAPK1_ST	P25205	MCM3	P53355	DAPK1	S604	M603L	603	Missense	proximal	-1	no	9.212	9.191	EPSD	COSMIC	8.849	Down-regulation
CAMK_DAPK_DAPK_DAPK1_ST	P25205	MCM3	P53355	DAPK1	S611	P612S	612	Missense	proximal	1	no	9.748	8.821	EPSD	COSMIC	8.849	Loss
CAMK_DAPK_DAPK_DAPK1_ST	P25205	MCM3	P53355	DAPK1	S611	P612A	612	Missense	proximal	1	no	9.748	9.330	EPSD	COSMIC	8.849	Down-regulation
CAMK_DAPK_DAPK_DAPK1_ST	P25205	MCM3	P53355	DAPK1	S611	R616Q	616	Missense	distal	5	no	9.748	10.381	EPSD	COSMIC	8.849	Up-regulation
CAMK_DAPK_DAPK_DAPK1_ST	P25205	MCM3	P53355	DAPK1	S611	T617A	617	Missense	distal	6	no	9.748	8.763	EPSD	COSMIC	8.849	Loss
CAMK_DAPK_DAPK_DAPK1_ST	P25205	MCM3	P53355	DAPK1	S611	A608T	608	Missense	distal	-3	no	9.748	13.823	EPSD	COSMIC	8.849	Up-regulation
CAMK_DAPK_DAPK_DAPK1_ST	P25205	MCM3	P53355	DAPK1	T620	R616Q	616	Missense	distal	-4	no	9.860	9.662	EPSD	COSMIC	8.849	Down-regulation
CAMK_DAPK_DAPK_DAPK1_ST	P25205	MCM3	P53355	DAPK1	T620	T617A	617	Missense	distal	-3	no	9.860	5.785	EPSD	COSMIC	8.849	Loss
CAMK_DAPK_DAPK_DAPK1_ST	P25205	MCM3	P53355	DAPK1	T620	A627S	627	Missense	distal	7	no	9.860	10.646	EPSD	COSMIC	8.849	Up-regulation
CAMK_DAPK_DAPK_DAPK1_ST	P25205	MCM3	P53355	DAPK1	T620	T626S	626	Missense	distal	6	no	9.860	7.719	EPSD	COSMIC;CCLE	8.849	Loss
CAMK_DAPK_DAPK_DAPK1_ST	P25205	MCM3	P53355	DAPK1	T620	A625V	625	Missense	distal	5	no	9.860	10.110	EPSD	COSMIC	8.849	Up-regulation
CAMK_DAPK_DAPK_DAPK1_ST	P25205	MCM3	P53355	DAPK1	T674	R667Q	667	Missense	distal	-7	no	9.219	8.056	EPSD	COSMIC	8.849	Loss
CAMK_DAPK_DAPK_DAPK1_ST	P25205	MCM3	P53355	DAPK1	T674	D676N	676	Missense	proximal	2	no	9.219	9.587	EPSD	COSMIC	8.849	Up-regulation
CAMK_DAPK_DAPK_DAPK1_ST	P25205	MCM3	P53355	DAPK1	T674	E673K	673	Missense	proximal	-1	no	9.219	9.605	EPSD	COSMIC	8.849	Up-regulation
CAMK_DAPK_DAPK_DAPK1_ST	P25205	MCM3	P53355	DAPK1	T674	E669K	669	Missense	distal	-5	no	9.219	9.203	EPSD	COSMIC	8.849	Down-regulation
CAMK_DAPK_DAPK_DAPK1_ST	P25205	MCM3	P53355	DAPK1	T694	R695H	695	Missense	proximal	1	no	10.337	9.787	EPSD	COSMIC	8.849	Down-regulation
CAMK_DAPK_DAPK_DAPK1_ST	P25205	MCM3	P53355	DAPK1	T694	K688N	688	Missense	distal	-6	no	10.337	11.562	EPSD	COSMIC	8.849	Up-regulation
CAMK_DAPK_DAPK_DAPK1_ST	P25205	MCM3	P53355	DAPK1	T694	D701N	701	Missense	distal	7	no	10.337	10.536	EPSD	COSMIC	8.849	Up-regulation
CAMK_DAPK_DAPK_DAPK1_ST	P25205	MCM3	P53355	DAPK1	T694	R695L	695	Missense	proximal	1	no	10.337	9.981	EPSD	COSMIC	8.849	Down-regulation
CAMK_DAPK_DAPK_DAPK1_ST	P25205	MCM3	P53355	DAPK1	T694	R695C	695	Missense	proximal	1	no	10.337	10.545	EPSD	COSMIC	8.849	Up-regulation
CAMK_DAPK_DAPK_DAPK1_ST	P09493	TPM1	P53355	DAPK1	T108	A109V	109	Missense	proximal	1	no	10.333	9.919	EPSD	COSMIC	8.849	Down-regulation
CAMK_DAPK_DAPK_DAPK1_ST	P09493	TPM1	P53355	DAPK1	T201	L207P	207	Missense	distal	6	no	7.774	8.878	EPSD	COSMIC	8.849	Gain
CAMK_DAPK_DAPK_DAPK1_ST	P09493	TPM1	P53355	DAPK1	S206	V200M	200	Missense	distal	-6	no	7.987	9.249	EPSD	COSMIC	8.849	Gain
CAMK_DAPK_DAPK_DAPK1_ST	Q13224	GRIN2B	P53355	DAPK1	S770	D777N	777	Missense	distal	7	no	9.388	9.587	EPSD	COSMIC	8.849	Up-regulation
CAMK_DAPK_DAPK_DAPK1_ST	Q13224	GRIN2B	P53355	DAPK1	S770	I766N	766	Missense	distal	-4	no	9.388	9.462	EPSD	COSMIC	8.849	Up-regulation
CAMK_DAPK_DAPK_DAPK1_ST	Q13224	GRIN2B	P53355	DAPK1	S770	R774H	774	Missense	distal	4	no	9.388	10.711	EPSD	COSMIC	8.849	Up-regulation
CAMK_DAPK_DAPK_DAPK1_ST	Q13224	GRIN2B	P53355	DAPK1	S770	V776M	776	Missense	distal	6	no	9.388	10.010	EPSD	COSMIC	8.849	Up-regulation
CAMK_DAPK_DAPK_DAPK1_ST	Q13224	GRIN2B	P53355	DAPK1	S865	I864V	864	Missense	proximal	-1	no	9.141	9.590	EPSD	COSMIC	8.849	Up-regulation
CAMK_DAPK_DAPK_DAPK1_ST	Q13224	GRIN2B	P53355	DAPK1	S882	E879K	879	Missense	distal	-3	no	8.702	10.639	EPSD	COSMIC	8.849	Gain
CAMK_DAPK_DAPK_DAPK1_ST	Q13224	GRIN2B	P53355	DAPK1	T894	T888S	888	Missense	distal	-6	no	9.847	10.765	EPSD	COSMIC	8.849	Up-regulation
CAMK_DAPK_DAPK_DAPK1_ST	Q13224	GRIN2B	P53355	DAPK1	T894	N893I	893	Missense	proximal	-1	no	9.847	9.336	EPSD	COSMIC	8.849	Down-regulation
CAMK_DAPK_DAPK_DAPK1_ST	Q13224	GRIN2B	P53355	DAPK1	T894	T890I	890	Missense	distal	-4	no	9.847	9.713	EPSD	COSMIC	8.849	Down-regulation
CAMK_DAPK_DAPK_DAPK1_ST	Q13224	GRIN2B	P53355	DAPK1	T894	P887H	887	Missense	distal	-7	no	9.847	10.598	EPSD	COSMIC	8.849	Up-regulation
CAMK_DAPK_DAPK_DAPK1_ST	Q13224	GRIN2B	P53355	DAPK1	S1166	R1164H	1164	Missense	proximal	-2	no	9.263	7.571	EPSD	COSMIC	8.849	Loss
CAMK_DAPK_DAPK_DAPK1_ST	Q13224	GRIN2B	P53355	DAPK1	S1166	D1165N	1165	Missense	proximal	-1	no	9.263	9.850	EPSD	COSMIC	8.849	Up-regulation
CAMK_DAPK_DAPK_DAPK1_ST	Q13224	GRIN2B	P53355	DAPK1	S1166	V1167I	1167	Missense	proximal	1	no	9.263	9.755	EPSD	COSMIC	8.849	Up-regulation
CAMK_DAPK_DAPK_DAPK1_ST	Q13224	GRIN2B	P53355	DAPK1	S1166	R1164S	1164	Missense	proximal	-2	no	9.263	7.887	EPSD	COSMIC	8.849	Loss
CAMK_DAPK_DAPK_DAPK1_ST	Q13224	GRIN2B	P53355	DAPK1	S1168	D1165N	1165	Missense	distal	-3	no	8.012	9.331	EPSD	COSMIC	8.849	Gain
CAMK_DAPK_DAPK_DAPK1_ST	Q13224	GRIN2B	P53355	DAPK1	S1303	S1303F	1303	Missense	central	0	yes	18.959	0.000	PhosphoSitePlus	COSMIC	8.849	Loss
CAMK_DAPK_DAPK_DAPK1_ST	Q13224	GRIN2B	P53355	DAPK1	S1303	D1309N	1309	Missense	distal	6	no	18.959	19.057	PhosphoSitePlus	COSMIC	8.849	Up-regulation
CAMK_DAPK_DAPK_DAPK1_ST	Q13224	GRIN2B	P53355	DAPK1	S1303	R1299L	1299	Missense	distal	-4	no	18.959	18.679	PhosphoSitePlus	COSMIC	8.849	Down-regulation
CAMK_DAPK_DAPK_DAPK1_ST	Q13224	GRIN2B	P53355	DAPK1	S1323	L1317M	1317	Missense	distal	-6	no	10.042	11.553	EPSD	COSMIC	8.849	Up-regulation
CAMK_DAPK_DAPK_DAPK1_ST	Q13224	GRIN2B	P53355	DAPK1	S1323	P1319T	1319	Missense	distal	-4	no	10.042	10.314	EPSD	COSMIC	8.849	Up-regulation
CAMK_DAPK_DAPK_DAPK1_ST	Q13224	GRIN2B	P53355	DAPK1	S1323	K1327N	1327	Missense	distal	4	no	10.042	9.782	EPSD	COSMIC	8.849	Down-regulation
CAMK_DAPK_DAPK_DAPK1_ST	Q13224	GRIN2B	P53355	DAPK1	S1323	V1322I	1322	Missense	proximal	-1	no	10.042	9.593	EPSD	COSMIC	8.849	Down-regulation
CAMK_DAPK_DAPK_DAPK1_ST	Q13224	GRIN2B	P53355	DAPK1	S1323	R1320C	1320	Missense	distal	-3	no	10.042	5.215	EPSD	COSMIC;CCLE	8.849	Loss
CAMK_DAPK_DAPK_DAPK1_ST	Q13224	GRIN2B	P53355	DAPK1	S1452	G1449R	1449	Missense	distal	-3	no	4.555	9.203	EPSD	COSMIC	8.849	Gain
CAMK_DAPK_DAPK_DAPK1_ST	Q13224	GRIN2B	P53355	DAPK1	S1469	P1462S	1462	Missense	distal	-7	no	9.651	8.539	EPSD	COSMIC	8.849	Loss
CAMK_DAPK_DAPK_DAPK1_ST	Q13224	GRIN2B	P53355	DAPK1	S1469	H1472Y	1472	Missense	distal	3	no	9.651	9.704	EPSD	COSMIC	8.849	Up-regulation
CAMK_DAPK_DAPK_DAPK1_ST	Q13224	GRIN2B	P53355	DAPK1	S1469	F1465L	1465	Missense	distal	-4	no	9.651	9.637	EPSD	COSMIC	8.849	Down-regulation
CAMK_PKD_PRKD1_ST	Q8WUI4	HDAC7	Q15139	PRKD1	S42	R41H	41	Missense	proximal	-1	no	5.084	4.971	EPSD	COSMIC	4.507	Down-regulation
CAMK_PKD_PRKD1_ST	Q8WUI4	HDAC7	Q15139	PRKD1	S42	L37M	37	Missense	distal	-5	no	5.084	3.457	EPSD	COSMIC	4.507	Loss
CAMK_PKD_PRKD1_ST	Q8WUI4	HDAC7	Q15139	PRKD1	S155	P149L	149	Missense	distal	-6	no	5.885	5.861	EPSD;PhosphoSitePlus	COSMIC	4.507	Down-regulation
CAMK_PKD_PRKD1_ST	Q8WUI4	HDAC7	Q15139	PRKD1	S155	P149T	149	Missense	distal	-6	no	5.885	5.877	EPSD;PhosphoSitePlus	COSMIC	4.507	Down-regulation
CAMK_PKD_PRKD1_ST	Q8WUI4	HDAC7	Q15139	PRKD1	S155	K160N	160	Missense	distal	5	no	5.885	5.860	EPSD;PhosphoSitePlus	COSMIC	4.507	Down-regulation
CAMK_PKD_PRKD1_ST	Q8WUI4	HDAC7	Q15139	PRKD1	S155	P157L	157	Missense	proximal	2	no	5.885	5.849	EPSD;PhosphoSitePlus	COSMIC	4.507	Down-regulation
CAMK_PKD_PRKD1_ST	Q8WUI4	HDAC7	Q15139	PRKD1	S181	S181N	181	Missense	central	0	yes	8.641	0.000	EPSD	COSMIC	4.507	Loss
CAMK_PKD_PRKD1_ST	Q8WUI4	HDAC7	Q15139	PRKD1	S181	R187W	187	Missense	distal	6	no	8.641	8.673	EPSD	COSMIC	4.507	Up-regulation
CAMK_PKD_PRKD1_ST	Q8WUI4	HDAC7	Q15139	PRKD1	S181	S181R	181	Missense	central	0	yes	8.641	0.000	EPSD	COSMIC	4.507	Loss
CAMK_PKD_PRKD1_ST	Q8WUI4	HDAC7	Q15139	PRKD1	S181	K179E	179	Missense	proximal	-2	no	8.641	7.860	EPSD	COSMIC	4.507	Down-regulation
CAMK_PKD_PRKD1_ST	Q8WUI4	HDAC7	Q15139	PRKD1	S181	R178Q	178	Missense	distal	-3	no	8.641	4.229	EPSD	COSMIC	4.507	Loss
CAMK_PKD_PRKD1_ST	Q8WUI4	HDAC7	Q15139	PRKD1	S181	P184L	184	Missense	distal	3	no	8.641	8.643	EPSD	COSMIC	4.507	Up-regulation
CAMK_PKD_PRKD1_ST	Q8WUI4	HDAC7	Q15139	PRKD1	S181	P175L	175	Missense	distal	-6	no	8.641	8.617	EPSD	COSMIC	4.507	Down-regulation
CAMK_PKD_PRKD1_ST	Q8WUI4	HDAC7	Q15139	PRKD1	S181	L186R	186	Missense	distal	5	no	8.641	8.718	EPSD	COSMIC	4.507	Up-regulation
CAMK_PKD_PRKD1_ST	Q8WUI4	HDAC7	Q15139	PRKD1	S345	E342K	342	Missense	distal	-3	no	4.386	5.836	EPSD	COSMIC	4.507	Gain
CAMK_PKD_PRKD1_ST	Q8WUI4	HDAC7	Q15139	PRKD1	S354	S347C	347	Missense	distal	-7	no	4.798	4.626	EPSD	COSMIC	4.507	Down-regulation
CAMK_PKD_PRKD1_ST	Q8WUI4	HDAC7	Q15139	PRKD1	S354	R357C	357	Missense	distal	3	no	4.798	4.784	EPSD	COSMIC	4.507	Down-regulation
CAMK_PKD_PRKD1_ST	Q8WUI4	HDAC7	Q15139	PRKD1	S358	R357C	357	Missense	proximal	-1	no	9.781	9.589	EPSD;PhosphoSitePlus	COSMIC	4.507	Down-regulation
CAMK_PKD_PRKD1_ST	Q8WUI4	HDAC7	Q15139	PRKD1	S358	R355L	355	Missense	distal	-3	no	9.781	4.853	EPSD;PhosphoSitePlus	COSMIC	4.507	Down-regulation
CAMK_PKD_PRKD1_ST	Q8WUI4	HDAC7	Q15139	PRKD1	S464	A457S	457	Missense	distal	-7	no	5.640	5.548	EPSD	COSMIC	4.507	Down-regulation
CAMK_PKD_PRKD1_ST	Q8WUI4	HDAC7	Q15139	PRKD1	S464	R459T	459	Missense	distal	-5	no	5.640	4.914	EPSD	COSMIC	4.507	Down-regulation
CAMK_PKD_PRKD1_ST	Q8WUI4	HDAC7	Q15139	PRKD1	T465	R459T	459	Missense	distal	-6	no	5.412	5.390	EPSD	COSMIC	4.507	Down-regulation
CAMK_PKD_PRKD1_ST	Q8WUI4	HDAC7	Q15139	PRKD1	S482	R479W	479	Missense	distal	-3	no	6.658	1.286	EPSD	COSMIC	4.507	Loss
CAMK_PKD_PRKD1_ST	Q8WUI4	HDAC7	Q15139	PRKD1	S482	G477V	477	Missense	distal	-5	no	6.658	8.141	EPSD	COSMIC;CCLE	4.507	Up-regulation
CAMK_PKD_PRKD1_ST	Q8WUI4	HDAC7	Q15139	PRKD1	S482	P480A	480	Missense	proximal	-2	no	6.658	7.272	EPSD	COSMIC	4.507	Up-regulation
CAMK_PKD_PRKD1_ST	Q8WUI4	HDAC7	Q15139	PRKD1	S486	R479W	479	Missense	distal	-7	no	10.857	10.173	PhosphoSitePlus;EPSD	COSMIC	4.507	Down-regulation
CAMK_PKD_PRKD1_ST	Q8WUI4	HDAC7	Q15139	PRKD1	S486	P480A	480	Missense	distal	-6	no	10.857	10.870	PhosphoSitePlus;EPSD	COSMIC	4.507	Up-regulation
CAMK_PKD_PRKD1_ST	Q8WUI4	HDAC7	Q15139	PRKD1	S534	S534F	534	Missense	central	0	yes	6.677	0.000	EPSD	COSMIC	4.507	Loss
CAMK_PKD_PRKD1_ST	Q8WUI4	HDAC7	Q15139	PRKD1	S534	H531Y	531	Missense	distal	-3	no	6.677	4.720	EPSD	COSMIC	4.507	Down-regulation
CAMK_PKD_PRKD1_ST	Q8WUI4	HDAC7	Q15139	PRKD1	S550	R547C	547	Missense	distal	-3	no	6.392	2.295	EPSD	COSMIC	4.507	Loss
CAMK_PKD_PRKD1_ST	Q8WUI4	HDAC7	Q15139	PRKD1	S550	R554L	554	Missense	distal	4	no	6.392	6.401	EPSD	COSMIC;CCLE	4.507	Up-regulation
CAMK_PKD_PRKD1_ST	Q8WUI4	HDAC7	Q15139	PRKD1	S550	A545T	545	Missense	distal	-5	no	6.392	5.725	EPSD	COSMIC	4.507	Down-regulation
CAMK_PKD_PRKD1_ST	Q8WUI4	HDAC7	Q15139	PRKD1	S550	R554W	554	Missense	distal	4	no	6.392	6.417	EPSD	COSMIC	4.507	Up-regulation
CAMK_PKD_PRKD1_ST	Q8WUI4	HDAC7	Q15139	PRKD1	S550	R547H	547	Missense	distal	-3	no	6.392	2.406	EPSD	COSMIC;CCLE	4.507	Loss
CAMK_PKD_PRKD1_ST	Q8WUI4	HDAC7	Q15139	PRKD1	S573	R570G	570	Missense	distal	-3	no	8.292	3.526	EPSD	COSMIC	4.507	Loss
CAMK_PKD_PRKD1_ST	Q8WUI4	HDAC7	Q15139	PRKD1	S573	R568G	568	Missense	distal	-5	no	8.292	7.157	EPSD	COSMIC	4.507	Down-regulation
CAMK_PKD_PRKD1_ST	Q8WUI4	HDAC7	Q15139	PRKD1	S573	L567H	567	Missense	distal	-6	no	8.292	8.318	EPSD	COSMIC	4.507	Up-regulation
CAMK_PKD_PRKD1_ST	Q8WUI4	HDAC7	Q15139	PRKD1	S644	R639C	639	Missense	distal	-5	no	5.092	4.663	EPSD	COSMIC	4.507	Down-regulation
CAMK_PKD_PRKD1_ST	Q8WUI4	HDAC7	Q15139	PRKD1	S644	A649T	649	Missense	distal	5	no	5.092	5.015	EPSD	COSMIC;CCLE	4.507	Down-regulation
CAMK_PKD_PRKD1_ST	Q8WUI4	HDAC7	Q15139	PRKD1	S644	T646S	646	Missense	proximal	2	no	5.092	5.160	EPSD	COSMIC	4.507	Up-regulation
CAMK_PKD_PRKD1_ST	Q8WUI4	HDAC7	Q15139	PRKD1	S644	R639H	639	Missense	distal	-5	no	5.092	4.969	EPSD	COSMIC	4.507	Down-regulation
CAMK_PKD_PRKD1_ST	Q8WUI4	HDAC7	Q15139	PRKD1	S903	C897Y	897	Missense	distal	-6	no	6.132	6.115	EPSD	COSMIC	4.507	Down-regulation
CAMK_PKD_PRKD1_ST	Q8WUI4	HDAC7	Q15139	PRKD1	S903	R900C	900	Missense	distal	-3	no	6.132	2.035	EPSD	COSMIC	4.507	Loss
CAMK_PKD_PRKD1_ST	Q8WUI4	HDAC7	Q15139	PRKD1	S903	A902T	902	Missense	proximal	-1	no	6.132	5.984	EPSD	COSMIC	4.507	Down-regulation
CAMK_PKD_PRKD1_ST	P35670	ATP7B	Q15139	PRKD1	S23	P25L	25	Missense	proximal	2	no	4.625	4.590	EPSD	COSMIC	4.507	Down-regulation
CAMK_PKD_PRKD1_ST	P35670	ATP7B	Q15139	PRKD1	S23	P25S	25	Missense	proximal	2	no	4.625	4.668	EPSD	COSMIC	4.507	Up-regulation
CAMK_PKD_PRKD1_ST	P35670	ATP7B	Q15139	PRKD1	S23	R27H	27	Missense	distal	4	no	4.625	4.629	EPSD	COSMIC	4.507	Up-regulation
CAMK_PKD_PRKD1_ST	P35670	ATP7B	Q15139	PRKD1	S132	R136G	136	Missense	distal	4	no	4.484	4.514	EPSD	COSMIC	4.507	Gain
CAMK_PKD_PRKD1_ST	P35670	ATP7B	Q15139	PRKD1	S229	E225K	225	Missense	distal	-4	no	6.288	6.290	EPSD	COSMIC	4.507	Up-regulation
CAMK_PKD_PRKD1_ST	P35670	ATP7B	Q15139	PRKD1	S882	H889Y	889	Missense	distal	7	no	4.832	4.831	EPSD	COSMIC	4.507	Down-regulation
CAMK_PKD_PRKD1_ST	P35670	ATP7B	Q15139	PRKD1	S882	A879T	879	Missense	distal	-3	no	4.832	4.566	EPSD	COSMIC	4.507	Down-regulation
CAMK_PKD_PRKD1_ST	P35670	ATP7B	Q15139	PRKD1	S1066	G1061V	1061	Missense	distal	-5	no	3.133	4.616	EPSD	COSMIC	4.507	Gain
CAMK_PKD_PRKD1_ST	P35670	ATP7B	Q15139	PRKD1	S1121	A1124D	1124	Missense	distal	3	no	7.938	7.906	EPSD;PhosphoSitePlus	COSMIC	4.507	Down-regulation
CAMK_PKD_PRKD1_ST	P35670	ATP7B	Q15139	PRKD1	S1121	A1124S	1124	Missense	distal	3	no	7.938	7.932	EPSD;PhosphoSitePlus	COSMIC	4.507	Down-regulation
CAMK_PKD_PRKD1_ST	P35670	ATP7B	Q15139	PRKD1	S1121	S1116I	1116	Missense	distal	-5	no	7.938	8.545	EPSD;PhosphoSitePlus	COSMIC	4.507	Up-regulation
CAMK_PKD_PRKD1_ST	P35670	ATP7B	Q15139	PRKD1	S1121	P1123L	1123	Missense	proximal	2	no	7.938	7.902	EPSD;PhosphoSitePlus	COSMIC	4.507	Down-regulation
CAMK_PKD_PRKD1_ST	O15273	TCAP	Q15139	PRKD1	S157	A151E	151	Missense	distal	-6	no	9.788	9.778	PhosphoSitePlus;EPSD	COSMIC	4.507	Down-regulation
CAMK_PKD_PRKD1_ST	O15273	TCAP	Q15139	PRKD1	S161	Q165H	165	Missense	distal	4	no	10.113	10.114	EPSD;PhosphoSitePlus	COSMIC	4.507	Up-regulation
CAMK_PKD_PRKD1_ST	P35222	CTNNB1	Q15139	PRKD1	S23	Q28E	28	Missense	distal	5	no	4.718	4.685	EPSD	COSMIC	4.507	Down-regulation
CAMK_PKD_PRKD1_ST	P35222	CTNNB1	Q15139	PRKD1	S23	A21V	21	Missense	proximal	-2	no	4.718	2.562	EPSD	COSMIC	4.507	Loss
CAMK_PKD_PRKD1_ST	P35222	CTNNB1	Q15139	PRKD1	S23	A21T	21	Missense	proximal	-2	no	4.718	4.111	EPSD	COSMIC	4.507	Loss
CAMK_PKD_PRKD1_ST	P35222	CTNNB1	Q15139	PRKD1	S23	V22I	22	Missense	proximal	-1	no	4.718	4.724	EPSD	COSMIC	4.507	Up-regulation
CAMK_PKD_PRKD1_ST	P35222	CTNNB1	Q15139	PRKD1	S23	S29P	29	Missense	distal	6	no	4.718	4.738	EPSD	COSMIC	4.507	Up-regulation
CAMK_PKD_PRKD1_ST	P35222	CTNNB1	Q15139	PRKD1	S23	A20V	20	Missense	distal	-3	no	4.718	1.769	EPSD	COSMIC	4.507	Loss
CAMK_PKD_PRKD1_ST	P35222	CTNNB1	Q15139	PRKD1	S23	P16T	16	Missense	distal	-7	no	4.718	4.662	EPSD	COSMIC	4.507	Down-regulation
CAMK_PKD_PRKD1_ST	P35222	CTNNB1	Q15139	PRKD1	S23	D17H	17	Missense	distal	-6	no	4.718	4.737	EPSD	COSMIC	4.507	Up-regulation
CAMK_PKD_PRKD1_ST	P35222	CTNNB1	Q15139	PRKD1	S23	Q27H	27	Missense	distal	4	no	4.718	4.719	EPSD	COSMIC	4.507	Up-regulation
CAMK_PKD_PRKD1_ST	P35222	CTNNB1	Q15139	PRKD1	S23	S23N	23	Missense	central	0	yes	4.718	0.000	EPSD	COSMIC	4.507	Loss
CAMK_PKD_PRKD1_ST	P35222	CTNNB1	Q15139	PRKD1	S23	S29F	29	Missense	distal	6	no	4.718	4.766	EPSD	COSMIC	4.507	Up-regulation
CAMK_PKD_PRKD1_ST	P35222	CTNNB1	Q15139	PRKD1	S23	Y30C	30	Missense	distal	7	no	4.718	4.719	EPSD	COSMIC	4.507	Up-regulation
CAMK_PKD_PRKD1_ST	P35222	CTNNB1	Q15139	PRKD1	S23	S29Y	29	Missense	distal	6	no	4.718	4.769	EPSD	COSMIC	4.507	Up-regulation
CAMK_PKD_PRKD1_ST	P35222	CTNNB1	Q15139	PRKD1	S23	S23R	23	Missense	central	0	yes	4.718	0.000	EPSD	COSMIC	4.507	Loss
CAMK_PKD_PRKD1_ST	P35222	CTNNB1	Q15139	PRKD1	S23	H24Y	24	Missense	proximal	1	no	4.718	4.717	EPSD	COSMIC	4.507	Down-regulation
CAMK_PKD_PRKD1_ST	P35222	CTNNB1	Q15139	PRKD1	S23	W25R	25	Missense	proximal	2	no	4.718	4.866	EPSD	COSMIC	4.507	Up-regulation
CAMK_PKD_PRKD1_ST	P35222	CTNNB1	Q15139	PRKD1	S23	V22A	22	Missense	proximal	-1	no	4.718	4.897	EPSD	COSMIC	4.507	Up-regulation
CAMK_PKD_PRKD1_ST	P35222	CTNNB1	Q15139	PRKD1	S23	W25L	25	Missense	proximal	2	no	4.718	4.777	EPSD	COSMIC	4.507	Up-regulation
CAMK_PKD_PRKD1_ST	P35222	CTNNB1	Q15139	PRKD1	S23	S23G	23	Missense	central	0	yes	4.718	0.000	EPSD	COSMIC	4.507	Loss
CAMK_PKD_PRKD1_ST	P35222	CTNNB1	Q15139	PRKD1	S23	V22G	22	Missense	proximal	-1	no	4.718	4.603	EPSD	COSMIC	4.507	Down-regulation
CAMK_PKD_PRKD1_ST	P35222	CTNNB1	Q15139	PRKD1	S23	D17Y	17	Missense	distal	-6	no	4.718	4.712	EPSD	COSMIC	4.507	Down-regulation
CAMK_PKD_PRKD1_ST	P35222	CTNNB1	Q15139	PRKD1	S23	A21D	21	Missense	proximal	-2	no	4.718	2.487	EPSD	COSMIC	4.507	Loss
CAMK_PKD_PRKD1_ST	P35222	CTNNB1	Q15139	PRKD1	S23	P16L	16	Missense	distal	-7	no	4.718	4.306	EPSD	COSMIC	4.507	Loss
CAMK_PKD_PRKD1_ST	P35222	CTNNB1	Q15139	PRKD1	S23	Y30S	30	Missense	distal	7	no	4.718	4.719	EPSD	COSMIC	4.507	Up-regulation
CAMK_PKD_PRKD1_ST	P35222	CTNNB1	Q15139	PRKD1	S23	Q26R	26	Missense	distal	3	no	4.718	4.726	EPSD	COSMIC;GDSC;CCLE	4.507	Up-regulation
CAMK_PKD_PRKD1_ST	P35222	CTNNB1	Q15139	PRKD1	S23	R18K	18	Missense	distal	-5	no	4.718	3.695	EPSD	COSMIC	4.507	Loss
CAMK_PKD_PRKD1_ST	P35222	CTNNB1	Q15139	PRKD1	S23	Q28R	28	Missense	distal	5	no	4.718	4.741	EPSD	COSMIC	4.507	Up-regulation
CAMK_PKD_PRKD1_ST	P35222	CTNNB1	Q15139	PRKD1	S23	P16S	16	Missense	distal	-7	no	4.718	4.830	EPSD	COSMIC	4.507	Up-regulation
CAMK_PKD_PRKD1_ST	P35222	CTNNB1	Q15139	PRKD1	S23	A20T	20	Missense	distal	-3	no	4.718	4.452	EPSD	COSMIC	4.507	Loss
CAMK_PKD_PRKD1_ST	P35222	CTNNB1	Q15139	PRKD1	S23	S29T	29	Missense	distal	6	no	4.718	4.749	EPSD	COSMIC	4.507	Up-regulation
CAMK_PKD_PRKD1_ST	P35222	CTNNB1	Q15139	PRKD1	S23	K19D	19	Missense	distal	-4	no	4.718	4.709	EPSD	COSMIC	4.507	Down-regulation
CAMK_PKD_PRKD1_ST	P35222	CTNNB1	Q15139	PRKD1	S29	Q26R	26	Missense	distal	-3	no	2.593	7.005	EPSD	COSMIC;GDSC;CCLE	4.507	Gain
CAMK_PKD_PRKD1_ST	P35222	CTNNB1	Q15139	PRKD1	S45	P44S	44	Missense	proximal	-1	no	5.138	5.234	EPSD	COSMIC	4.507	Up-regulation
CAMK_PKD_PRKD1_ST	P35222	CTNNB1	Q15139	PRKD1	S45	A43V	43	Missense	proximal	-2	no	5.138	2.982	EPSD	COSMIC	4.507	Loss
CAMK_PKD_PRKD1_ST	P35222	CTNNB1	Q15139	PRKD1	S45	A39G	39	Missense	distal	-6	no	5.138	5.101	EPSD	COSMIC	4.507	Down-regulation
CAMK_PKD_PRKD1_ST	P35222	CTNNB1	Q15139	PRKD1	S45	N51T	51	Missense	distal	6	no	5.138	5.141	EPSD	COSMIC	4.507	Up-regulation
CAMK_PKD_PRKD1_ST	P35222	CTNNB1	Q15139	PRKD1	S45	N51S	51	Missense	distal	6	no	5.138	5.110	EPSD	COSMIC	4.507	Down-regulation
CAMK_PKD_PRKD1_ST	P35222	CTNNB1	Q15139	PRKD1	S45	G38A	38	Missense	distal	-7	no	5.138	5.612	EPSD	COSMIC	4.507	Up-regulation
CAMK_PKD_PRKD1_ST	P35222	CTNNB1	Q15139	PRKD1	S45	T40I	40	Missense	distal	-5	no	5.138	6.087	EPSD	COSMIC	4.507	Up-regulation
CAMK_PKD_PRKD1_ST	P35222	CTNNB1	Q15139	PRKD1	S45	P44A	44	Missense	proximal	-1	no	5.138	5.269	EPSD	COSMIC	4.507	Up-regulation
CAMK_PKD_PRKD1_ST	P35222	CTNNB1	Q15139	PRKD1	S45	T41P	41	Missense	distal	-4	no	5.138	5.140	EPSD	COSMIC	4.507	Up-regulation
CAMK_PKD_PRKD1_ST	P35222	CTNNB1	Q15139	PRKD1	S45	K49R	49	Missense	distal	4	no	5.138	5.128	EPSD	COSMIC	4.507	Down-regulation
CAMK_PKD_PRKD1_ST	P35222	CTNNB1	Q15139	PRKD1	S45	T42R	42	Missense	distal	-3	no	5.138	8.650	EPSD	COSMIC	4.507	Up-regulation
CAMK_PKD_PRKD1_ST	P35222	CTNNB1	Q15139	PRKD1	S45	S45A	45	Missense	central	0	yes	5.138	0.000	EPSD	COSMIC	4.507	Loss
CAMK_PKD_PRKD1_ST	P35222	CTNNB1	Q15139	PRKD1	S45	G48S	48	Missense	distal	3	no	5.138	5.163	EPSD	COSMIC	4.507	Up-regulation
CAMK_PKD_PRKD1_ST	P35222	CTNNB1	Q15139	PRKD1	S45	T40A	40	Missense	distal	-5	no	5.138	5.805	EPSD	COSMIC	4.507	Up-regulation
CAMK_PKD_PRKD1_ST	P35222	CTNNB1	Q15139	PRKD1	S45	A43T	43	Missense	proximal	-2	no	5.138	4.531	EPSD	COSMIC	4.507	Down-regulation
CAMK_PKD_PRKD1_ST	P35222	CTNNB1	Q15139	PRKD1	S45	P44L	44	Missense	proximal	-1	no	5.138	5.202	EPSD	COSMIC	4.507	Up-regulation
CAMK_PKD_PRKD1_ST	P35222	CTNNB1	Q15139	PRKD1	S45	T42I	42	Missense	distal	-3	no	5.138	3.566	EPSD	COSMIC	4.507	Loss
CAMK_PKD_PRKD1_ST	P35222	CTNNB1	Q15139	PRKD1	S45	T42S	42	Missense	distal	-3	no	5.138	4.213	EPSD	COSMIC	4.507	Loss
CAMK_PKD_PRKD1_ST	P35222	CTNNB1	Q15139	PRKD1	S45	T42K	42	Missense	distal	-3	no	5.138	5.978	EPSD	COSMIC	4.507	Up-regulation
CAMK_PKD_PRKD1_ST	P35222	CTNNB1	Q15139	PRKD1	S45	S47G	47	Missense	proximal	2	no	5.138	4.982	EPSD	COSMIC	4.507	Down-regulation
CAMK_PKD_PRKD1_ST	P35222	CTNNB1	Q15139	PRKD1	S45	G48V	48	Missense	distal	3	no	5.138	5.152	EPSD	COSMIC	4.507	Up-regulation
CAMK_PKD_PRKD1_ST	P35222	CTNNB1	Q15139	PRKD1	S45	S47N	47	Missense	proximal	2	no	5.138	5.054	EPSD	COSMIC	4.507	Down-regulation
CAMK_PKD_PRKD1_ST	P35222	CTNNB1	Q15139	PRKD1	S45	A39T	39	Missense	distal	-6	no	5.138	5.117	EPSD	COSMIC	4.507	Down-regulation
CAMK_PKD_PRKD1_ST	P35222	CTNNB1	Q15139	PRKD1	S45	K49T	49	Missense	distal	4	no	5.138	5.145	EPSD	COSMIC	4.507	Up-regulation
CAMK_PKD_PRKD1_ST	P35222	CTNNB1	Q15139	PRKD1	S45	G50D	50	Missense	distal	5	no	5.138	5.164	EPSD	COSMIC	4.507	Up-regulation
CAMK_PKD_PRKD1_ST	P35222	CTNNB1	Q15139	PRKD1	S45	A43P	43	Missense	proximal	-2	no	5.138	4.525	EPSD	COSMIC	4.507	Down-regulation
CAMK_PKD_PRKD1_ST	P35222	CTNNB1	Q15139	PRKD1	S45	G38P	38	Missense	distal	-7	no	5.138	5.408	EPSD	COSMIC	4.507	Up-regulation
CAMK_PKD_PRKD1_ST	P35222	CTNNB1	Q15139	PRKD1	S45	G38D	38	Missense	distal	-7	no	5.138	5.079	EPSD	COSMIC	4.507	Down-regulation
CAMK_PKD_PRKD1_ST	P35222	CTNNB1	Q15139	PRKD1	S45	T42A	42	Missense	distal	-3	no	5.138	5.404	EPSD	COSMIC	4.507	Up-regulation
CAMK_PKD_PRKD1_ST	P35222	CTNNB1	Q15139	PRKD1	S45	S47L	47	Missense	proximal	2	no	5.138	5.060	EPSD	COSMIC	4.507	Down-regulation
CAMK_PKD_PRKD1_ST	P35222	CTNNB1	Q15139	PRKD1	S45	T40S	40	Missense	distal	-5	no	5.138	5.481	EPSD	COSMIC	4.507	Up-regulation
CAMK_PKD_PRKD1_ST	P35222	CTNNB1	Q15139	PRKD1	S45	K49L	49	Missense	distal	4	no	5.138	5.137	EPSD	COSMIC	4.507	Down-regulation
CAMK_PKD_PRKD1_ST	P35222	CTNNB1	Q15139	PRKD1	S45	S47T	47	Missense	proximal	2	no	5.138	5.070	EPSD	COSMIC	4.507	Down-regulation
CAMK_PKD_PRKD1_ST	P35222	CTNNB1	Q15139	PRKD1	S45	T41S	41	Missense	distal	-4	no	5.138	5.143	EPSD	COSMIC	4.507	Up-regulation
CAMK_PKD_PRKD1_ST	P35222	CTNNB1	Q15139	PRKD1	S45	T42Q	42	Missense	distal	-3	no	5.138	4.237	EPSD	COSMIC	4.507	Loss
CAMK_PKD_PRKD1_ST	P35222	CTNNB1	Q15139	PRKD1	S45	S47C	47	Missense	proximal	2	no	5.138	5.081	EPSD	COSMIC	4.507	Down-regulation
CAMK_PKD_PRKD1_ST	P35222	CTNNB1	Q15139	PRKD1	S45	K49E	49	Missense	distal	4	no	5.138	5.139	EPSD	COSMIC	4.507	Up-regulation
CAMK_PKD_PRKD1_ST	P35222	CTNNB1	Q15139	PRKD1	S45	S47R	47	Missense	proximal	2	no	5.138	5.150	EPSD	COSMIC	4.507	Up-regulation
CAMK_PKD_PRKD1_ST	P35222	CTNNB1	Q15139	PRKD1	S45	A39V	39	Missense	distal	-6	no	5.138	5.113	EPSD	COSMIC	4.507	Down-regulation
CAMK_PKD_PRKD1_ST	P35222	CTNNB1	Q15139	PRKD1	S45	S45E	45	Missense	central	0	yes	5.138	0.000	EPSD	COSMIC	4.507	Loss
CAMK_PKD_PRKD1_ST	P35222	CTNNB1	Q15139	PRKD1	S45	G50S	50	Missense	distal	5	no	5.138	5.262	EPSD	COSMIC	4.507	Up-regulation
CAMK_PKD_PRKD1_ST	P35222	CTNNB1	Q15139	PRKD1	S45	S45N	45	Missense	central	0	yes	5.138	0.000	EPSD	COSMIC	4.507	Loss
CAMK_PKD_PRKD1_ST	P35222	CTNNB1	Q15139	PRKD1	S45	G38X	38	Missense	distal	-7	no	5.138	5.285	EPSD	COSMIC	4.507	Up-regulation
CAMK_PKD_PRKD1_ST	P35222	CTNNB1	Q15139	PRKD1	S45	L46Q	46	Missense	proximal	1	no	5.138	5.139	EPSD	COSMIC	4.507	Up-regulation
CAMK_PKD_PRKD1_ST	P35222	CTNNB1	Q15139	PRKD1	S45	S45X	45	Missense	central	0	yes	5.138	0.000	EPSD	COSMIC	4.507	Loss
CAMK_PKD_PRKD1_ST	P35222	CTNNB1	Q15139	PRKD1	S45	G38S	38	Missense	distal	-7	no	5.138	5.520	EPSD	COSMIC	4.507	Up-regulation
CAMK_PKD_PRKD1_ST	P35222	CTNNB1	Q15139	PRKD1	S45	P44I	44	Missense	proximal	-1	no	5.138	5.095	EPSD	COSMIC	4.507	Down-regulation
CAMK_PKD_PRKD1_ST	P35222	CTNNB1	Q15139	PRKD1	S45	S47I	47	Missense	proximal	2	no	5.138	5.053	EPSD	COSMIC	4.507	Down-regulation
CAMK_PKD_PRKD1_ST	P35222	CTNNB1	Q15139	PRKD1	S45	S47Y	47	Missense	proximal	2	no	5.138	4.968	EPSD	COSMIC	4.507	Down-regulation
CAMK_PKD_PRKD1_ST	P35222	CTNNB1	Q15139	PRKD1	S45	T40P	40	Missense	distal	-5	no	5.138	4.899	EPSD	COSMIC	4.507	Down-regulation
CAMK_PKD_PRKD1_ST	P35222	CTNNB1	Q15139	PRKD1	S179	H176R	176	Missense	distal	-3	no	3.419	7.406	EPSD	COSMIC	4.507	Gain
CAMK_PKD_PRKD1_ST	P35222	CTNNB1	Q15139	PRKD1	T332	V325I	325	Missense	distal	-7	no	6.119	6.184	EPSD	COSMIC	4.507	Up-regulation
CAMK_PKD_PRKD1_ST	P35222	CTNNB1	Q15139	PRKD1	T332	L336V	336	Missense	distal	4	no	6.119	6.122	EPSD	COSMIC	4.507	Up-regulation
CAMK_PKD_PRKD1_ST	P35222	CTNNB1	Q15139	PRKD1	T332	I327T	327	Missense	distal	-5	no	6.119	5.170	EPSD	COSMIC	4.507	Down-regulation
CAMK_PKD_PRKD1_ST	P35222	CTNNB1	Q15139	PRKD1	T332	I327V	327	Missense	distal	-5	no	6.119	6.242	EPSD	COSMIC	4.507	Up-regulation
CAMK_PKD_PRKD1_ST	P35222	CTNNB1	Q15139	PRKD1	T332	K335R	335	Missense	distal	3	no	6.119	6.133	EPSD	COSMIC	4.507	Up-regulation
CAMK_PKD_PRKD1_ST	P35222	CTNNB1	Q15139	PRKD1	T332	K335Q	335	Missense	distal	3	no	6.119	6.126	EPSD	COSMIC	4.507	Up-regulation
CAMK_PKD_PRKD1_ST	P35222	CTNNB1	Q15139	PRKD1	T332	L337P	337	Missense	distal	5	no	6.119	6.130	EPSD	COSMIC	4.507	Up-regulation
CAMK_PKD_PRKD1_ST	P35222	CTNNB1	Q15139	PRKD1	T472	L468V	468	Missense	distal	-4	no	6.729	6.728	EPSD	COSMIC	4.507	Down-regulation
CAMK_PKD_PRKD1_ST	P35222	CTNNB1	Q15139	PRKD1	T472	A478T	478	Missense	distal	6	no	6.729	6.760	EPSD	COSMIC	4.507	Up-regulation
CAMK_PKD_PRKD1_ST	P35222	CTNNB1	Q15139	PRKD1	T472	H475Q	475	Missense	distal	3	no	6.729	6.730	EPSD	COSMIC	4.507	Up-regulation
CAMK_PKD_PRKD1_ST	P35222	CTNNB1	Q15139	PRKD1	T472	L471Q	471	Missense	proximal	-1	no	6.729	6.719	EPSD	COSMIC	4.507	Down-regulation
CAMK_PKD_PRKD1_ST	P35222	CTNNB1	Q15139	PRKD1	T472	R469C	469	Missense	distal	-3	no	6.729	2.632	EPSD	COSMIC	4.507	Loss
CAMK_PKD_PRKD1_ST	P35222	CTNNB1	Q15139	PRKD1	T472	A478G	478	Missense	distal	6	no	6.729	6.782	EPSD	COSMIC	4.507	Up-regulation
CAMK_PKD_PRKD1_ST	P35222	CTNNB1	Q15139	PRKD1	S473	E479K	479	Missense	distal	6	no	4.951	4.952	EPSD	COSMIC	4.507	Up-regulation
CAMK_PKD_PRKD1_ST	P35222	CTNNB1	Q15139	PRKD1	S473	T472S	472	Missense	proximal	-1	no	4.951	5.065	EPSD	COSMIC	4.507	Up-regulation
CAMK_PKD_PRKD1_ST	P35222	CTNNB1	Q15139	PRKD1	S473	L468V	468	Missense	distal	-5	no	4.951	3.418	EPSD	COSMIC	4.507	Loss
CAMK_PKD_PRKD1_ST	P35222	CTNNB1	Q15139	PRKD1	S473	A478T	478	Missense	distal	5	no	4.951	4.873	EPSD	COSMIC	4.507	Down-regulation
CAMK_PKD_PRKD1_ST	P35222	CTNNB1	Q15139	PRKD1	S473	H475Q	475	Missense	proximal	2	no	4.951	4.972	EPSD	COSMIC	4.507	Up-regulation
CAMK_PKD_PRKD1_ST	P35222	CTNNB1	Q15139	PRKD1	S473	L471Q	471	Missense	proximal	-2	no	4.951	6.092	EPSD	COSMIC	4.507	Up-regulation
CAMK_PKD_PRKD1_ST	P35222	CTNNB1	Q15139	PRKD1	S473	R469C	469	Missense	distal	-4	no	4.951	4.943	EPSD	COSMIC	4.507	Down-regulation
CAMK_PKD_PRKD1_ST	P35222	CTNNB1	Q15139	PRKD1	S473	A478G	478	Missense	distal	5	no	4.951	4.805	EPSD	COSMIC	4.507	Down-regulation
CAMK_PKD_PRKD1_ST	P35222	CTNNB1	Q15139	PRKD1	S552	T551K	551	Missense	proximal	-1	no	8.246	8.298	EPSD	COSMIC	4.507	Up-regulation
CAMK_PKD_PRKD1_ST	P35222	CTNNB1	Q15139	PRKD1	S552	R549C	549	Missense	distal	-3	no	8.246	4.149	EPSD	COSMIC	4.507	Loss
CAMK_PKD_PRKD1_ST	P35222	CTNNB1	Q15139	PRKD1	S552	Q545K	545	Missense	distal	-7	no	8.246	8.260	EPSD	COSMIC	4.507	Up-regulation
CAMK_PKD_PRKD1_ST	P35222	CTNNB1	Q15139	PRKD1	S552	Q558H	558	Missense	distal	6	no	8.246	8.252	EPSD	COSMIC	4.507	Up-regulation
CAMK_PKD_PRKD1_ST	P35222	CTNNB1	Q15139	PRKD1	S552	G555A	555	Missense	distal	3	no	8.246	8.277	EPSD	COSMIC	4.507	Up-regulation
CAMK_PKD_PRKD1_ST	P35222	CTNNB1	Q15139	PRKD1	S552	R550H	550	Missense	proximal	-2	no	8.246	6.300	EPSD	COSMIC	4.507	Down-regulation
CAMK_PKD_PRKD1_ST	P35222	CTNNB1	Q15139	PRKD1	S552	R550L	550	Missense	proximal	-2	no	8.246	5.138	EPSD	COSMIC	4.507	Down-regulation
CAMK_PKD_PRKD1_ST	P35222	CTNNB1	Q15139	PRKD1	S552	D546E	546	Missense	distal	-6	no	8.246	8.266	EPSD	COSMIC	4.507	Up-regulation
CAMK_PKD_PRKD1_ST	P35222	CTNNB1	Q15139	PRKD1	S552	S552F	552	Missense	central	0	yes	8.246	0.000	EPSD	COSMIC	4.507	Loss
CAMK_PKD_PRKD1_ST	P35222	CTNNB1	Q15139	PRKD1	S552	T547S	547	Missense	distal	-5	no	8.246	8.589	EPSD	COSMIC	4.507	Up-regulation
CAMK_PKD_PRKD1_ST	P35222	CTNNB1	Q15139	PRKD1	S552	G554D	554	Missense	proximal	2	no	8.246	8.272	EPSD	COSMIC	4.507	Up-regulation
CAMK_PKD_PRKD1_ST	P35222	CTNNB1	Q15139	PRKD1	S552	R550Q	550	Missense	proximal	-2	no	8.246	6.279	EPSD	COSMIC	4.507	Down-regulation
CAMK_PKD_PRKD1_ST	P35222	CTNNB1	Q15139	PRKD1	S552	T551I	551	Missense	proximal	-1	no	8.246	8.221	EPSD	COSMIC	4.507	Down-regulation
CAMK_PKD_PRKD1_ST	P35222	CTNNB1	Q15139	PRKD1	S675	R673W	673	Missense	proximal	-2	no	5.030	1.567	EPSD	COSMIC	4.507	Loss
CAMK_PKD_PRKD1_ST	P35222	CTNNB1	Q15139	PRKD1	S675	S680I	680	Missense	distal	5	no	5.030	4.967	EPSD	COSMIC	4.507	Down-regulation
CAMK_PKD_PRKD1_ST	P35222	CTNNB1	Q15139	PRKD1	S675	E677D	677	Missense	proximal	2	no	5.030	4.946	EPSD	COSMIC	4.507	Down-regulation
CAMK_PKD_PRKD1_ST	P35222	CTNNB1	Q15139	PRKD1	S675	R673H	673	Missense	proximal	-2	no	5.030	3.083	EPSD	COSMIC	4.507	Loss
CAMK_PKD_PRKD1_ST	P35222	CTNNB1	Q15139	PRKD1	S675	L678F	678	Missense	distal	3	no	5.030	5.013	EPSD	COSMIC	4.507	Down-regulation
CAMK_PKD_PRKD1_ST	P35222	CTNNB1	Q15139	PRKD1	S675	R673C	673	Missense	proximal	-2	no	5.030	2.422	EPSD	COSMIC	4.507	Loss
CAMK_PKD_PRKD1_ST	P35222	CTNNB1	Q15139	PRKD1	S718	S715R	715	Missense	distal	-3	no	0.666	5.102	EPSD	COSMIC	4.507	Gain
CAMK_PKD_PRKD1_ST	Q8WYL5	SSH1	Q15139	PRKD1	T11	A14T	14	Missense	distal	3	no	7.101	7.081	EPSD	COSMIC	4.507	Down-regulation
CAMK_PKD_PRKD1_ST	Q8WYL5	SSH1	Q15139	PRKD1	S17	A14T	14	Missense	distal	-3	no	4.625	4.359	EPSD	COSMIC	4.507	Loss
CAMK_PKD_PRKD1_ST	Q8WYL5	SSH1	Q15139	PRKD1	S39	S39N	39	Missense	central	0	yes	4.902	0.000	EPSD	COSMIC	4.507	Loss
CAMK_PKD_PRKD1_ST	Q8WYL5	SSH1	Q15139	PRKD1	S237	P235S	235	Missense	proximal	-2	no	6.430	6.752	EPSD	COSMIC	4.507	Up-regulation
CAMK_PKD_PRKD1_ST	Q8WYL5	SSH1	Q15139	PRKD1	S402	V397M	397	Missense	distal	-5	no	8.076	7.983	EPSD;PhosphoSitePlus	COSMIC	4.507	Down-regulation
CAMK_PKD_PRKD1_ST	Q8WYL5	SSH1	Q15139	PRKD1	S402	G396C	396	Missense	distal	-6	no	8.076	8.095	EPSD;PhosphoSitePlus	COSMIC	4.507	Up-regulation
CAMK_PKD_PRKD1_ST	Q8WYL5	SSH1	Q15139	PRKD1	T430	R427H	427	Missense	distal	-3	no	4.515	0.528	EPSD	COSMIC	4.507	Loss
CAMK_PKD_PRKD1_ST	Q8WYL5	SSH1	Q15139	PRKD1	T430	A434V	434	Missense	distal	4	no	4.515	4.531	EPSD	COSMIC	4.507	Up-regulation
CAMK_PKD_PRKD1_ST	Q8WYL5	SSH1	Q15139	PRKD1	T430	A434S	434	Missense	distal	4	no	4.515	4.522	EPSD	COSMIC	4.507	Up-regulation
CAMK_PKD_PRKD1_ST	Q8WYL5	SSH1	Q15139	PRKD1	S441	M437I	437	Missense	distal	-4	no	6.063	6.059	EPSD	COSMIC	4.507	Down-regulation
CAMK_PKD_PRKD1_ST	Q8WYL5	SSH1	Q15139	PRKD1	S441	A434V	434	Missense	distal	-7	no	6.063	5.552	EPSD	COSMIC	4.507	Down-regulation
CAMK_PKD_PRKD1_ST	Q8WYL5	SSH1	Q15139	PRKD1	S441	A434S	434	Missense	distal	-7	no	6.063	5.972	EPSD	COSMIC	4.507	Down-regulation
CAMK_PKD_PRKD1_ST	Q8WYL5	SSH1	Q15139	PRKD1	S441	R438L	438	Missense	distal	-3	no	6.063	1.136	EPSD	COSMIC	4.507	Loss
CAMK_PKD_PRKD1_ST	Q8WYL5	SSH1	Q15139	PRKD1	S441	R438H	438	Missense	distal	-3	no	6.063	2.077	EPSD	COSMIC	4.507	Loss
CAMK_PKD_PRKD1_ST	Q8WYL5	SSH1	Q15139	PRKD1	S441	R438C	438	Missense	distal	-3	no	6.063	1.966	EPSD	COSMIC	4.507	Loss
CAMK_PKD_PRKD1_ST	Q8WYL5	SSH1	Q15139	PRKD1	T462	R459H	459	Missense	distal	-3	no	6.368	2.381	EPSD	COSMIC;GDSC	4.507	Loss
CAMK_PKD_PRKD1_ST	Q8WYL5	SSH1	Q15139	PRKD1	S515	P517S	517	Missense	proximal	2	no	9.595	9.637	EPSD	COSMIC	4.507	Up-regulation
CAMK_PKD_PRKD1_ST	Q8WYL5	SSH1	Q15139	PRKD1	S515	R512W	512	Missense	distal	-3	no	9.595	4.222	EPSD	COSMIC	4.507	Loss
CAMK_PKD_PRKD1_ST	Q8WYL5	SSH1	Q15139	PRKD1	S583	R580Q	580	Missense	distal	-3	no	7.071	2.659	EPSD	COSMIC	4.507	Loss
CAMK_PKD_PRKD1_ST	Q8WYL5	SSH1	Q15139	PRKD1	S583	R580W	580	Missense	distal	-3	no	7.071	1.698	EPSD	COSMIC	4.507	Loss
CAMK_PKD_PRKD1_ST	Q8WYL5	SSH1	Q15139	PRKD1	S583	S576G	576	Missense	distal	-7	no	7.071	6.689	EPSD	COSMIC	4.507	Down-regulation
CAMK_PKD_PRKD1_ST	Q8WYL5	SSH1	Q15139	PRKD1	S834	V835M	835	Missense	proximal	1	no	9.355	9.356	EPSD	COSMIC	4.507	Up-regulation
CAMK_PKD_PRKD1_ST	Q8WYL5	SSH1	Q15139	PRKD1	S834	A840V	840	Missense	distal	6	no	9.355	9.381	EPSD	COSMIC	4.507	Up-regulation
CAMK_PKD_PRKD1_ST	Q8WYL5	SSH1	Q15139	PRKD1	S889	P887S	887	Missense	proximal	-2	no	4.497	4.819	EPSD	COSMIC;GDSC;CCLE	4.507	Gain
CAMK_PKD_PRKD1_ST	Q8WYL5	SSH1	Q15139	PRKD1	S910	D914N	914	Missense	distal	4	no	4.677	4.666	EPSD	COSMIC	4.507	Down-regulation
CAMK_PKD_PRKD1_ST	Q8WYL5	SSH1	Q15139	PRKD1	S910	R904H	904	Missense	distal	-6	no	4.677	4.664	EPSD	COSMIC	4.507	Down-regulation
CAMK_PKD_PRKD1_ST	Q8WYL5	SSH1	Q15139	PRKD1	S978	R975H	975	Missense	distal	-3	no	9.563	5.577	PhosphoSitePlus;EPSD	COSMIC	4.507	Down-regulation
CAMK_PKD_PRKD1_ST	Q8WYL5	SSH1	Q15139	PRKD1	S978	S971F	971	Missense	distal	-7	no	9.563	9.183	PhosphoSitePlus;EPSD	COSMIC	4.507	Down-regulation
CAMK_PKD_PRKD1_ST	Q8WYL5	SSH1	Q15139	PRKD1	S978	R975C	975	Missense	distal	-3	no	9.563	5.466	PhosphoSitePlus;EPSD	COSMIC;GDSC;CCLE	4.507	Down-regulation
CAMK_PKD_PRKD1_ST	Q8WYL5	SSH1	Q15139	PRKD1	S984	T986A	986	Missense	proximal	2	no	5.357	5.465	EPSD	COSMIC;GDSC;CCLE	4.507	Up-regulation
CAMK_PKD_PRKD1_ST	Q8WYL5	SSH1	Q15139	PRKD1	S984	E990K	990	Missense	distal	6	no	5.357	5.359	EPSD	COSMIC;GDSC;CCLE	4.507	Up-regulation
CAMK_PKD_PRKD1_ST	Q92934	BAD	Q15139	PRKD1	S74	A78E	78	Missense	distal	4	no	4.622	4.636	EPSD	COSMIC	4.507	Up-regulation
CAMK_PKD_PRKD1_ST	Q92934	BAD	Q15139	PRKD1	S75	A78E	78	Missense	distal	3	no	8.207	8.195	PhosphoSitePlus;EPSD	COSMIC	4.507	Down-regulation
CAMK_PKD_PRKD1_ST	Q92934	BAD	Q15139	PRKD1	S97	P102L	102	Missense	distal	5	no	6.387	6.376	EPSD	COSMIC	4.507	Down-regulation
CAMK_PKD_PRKD1_ST	Q92934	BAD	Q15139	PRKD1	S97	S97P	97	Missense	central	0	yes	6.387	0.000	EPSD	COSMIC	4.507	Loss
CAMK_PKD_PRKD1_ST	Q92934	BAD	Q15139	PRKD1	S97	P101S	101	Missense	distal	4	no	6.387	6.379	EPSD	COSMIC	4.507	Down-regulation
CAMK_PKD_PRKD1_ST	Q92934	BAD	Q15139	PRKD1	S99	P102L	102	Missense	distal	3	no	7.408	7.410	EPSD;PhosphoSitePlus	COSMIC	4.507	Up-regulation
CAMK_PKD_PRKD1_ST	Q92934	BAD	Q15139	PRKD1	S99	S97P	97	Missense	proximal	-2	no	7.408	7.086	EPSD;PhosphoSitePlus	COSMIC	4.507	Down-regulation
CAMK_PKD_PRKD1_ST	Q92934	BAD	Q15139	PRKD1	S99	R98H	98	Missense	proximal	-1	no	7.408	7.295	EPSD;PhosphoSitePlus	COSMIC	4.507	Down-regulation
CAMK_PKD_PRKD1_ST	Q92934	BAD	Q15139	PRKD1	S99	P101S	101	Missense	proximal	2	no	7.408	7.450	EPSD;PhosphoSitePlus	COSMIC	4.507	Up-regulation
CAMK_PKD_PRKD1_ST	Q92934	BAD	Q15139	PRKD1	S118	S124F	124	Missense	distal	6	no	7.427	7.475	EPSD;PhosphoSitePlus	COSMIC	4.507	Up-regulation
CAMK_PKD_PRKD1_ST	Q92934	BAD	Q15139	PRKD1	S134	K127N	127	Missense	distal	-7	no	10.798	10.450	EPSD	COSMIC	4.507	Down-regulation
CAMK_PKD_PRKD1_ST	Q92934	BAD	Q15139	PRKD1	S134	K133N	133	Missense	proximal	-1	no	10.798	10.701	EPSD	COSMIC	4.507	Down-regulation
CAMK_PKD_PRKD1_ST	Q92934	BAD	Q15139	PRKD1	S145	W147R	147	Missense	proximal	2	no	6.629	6.777	EPSD	COSMIC	4.507	Up-regulation
CAMK_PKD_PRKD1_ST	Q92934	BAD	Q15139	PRKD1	S164	R161S	161	Missense	distal	-3	no	8.811	4.374	EPSD	COSMIC;GDSC	4.507	Loss
CAMK_PKD_PRKD1_ST	Q92934	BAD	Q15139	PRKD1	S164	P166S	166	Missense	proximal	2	no	8.811	8.853	EPSD	COSMIC	4.507	Up-regulation
CAMK_PKD_PRKD1_ST	Q92934	BAD	Q15139	PRKD1	S164	R161G	161	Missense	distal	-3	no	8.811	4.044	EPSD	COSMIC	4.507	Loss
CAMK_PKD_PRKD1_ST	Q9UQL6	HDAC5	Q15139	PRKD1	S16	L20M	20	Missense	distal	4	no	5.812	5.808	EPSD	COSMIC	4.507	Down-regulation
CAMK_PKD_PRKD1_ST	Q9UQL6	HDAC5	Q15139	PRKD1	S16	R13W	13	Missense	distal	-3	no	5.812	0.439	EPSD	COSMIC	4.507	Loss
CAMK_PKD_PRKD1_ST	Q9UQL6	HDAC5	Q15139	PRKD1	S16	E18Q	18	Missense	proximal	2	no	5.812	5.853	EPSD	COSMIC	4.507	Up-regulation
CAMK_PKD_PRKD1_ST	Q9UQL6	HDAC5	Q15139	PRKD1	S16	G12R	12	Missense	distal	-4	no	5.812	5.825	EPSD	COSMIC	4.507	Up-regulation
CAMK_PKD_PRKD1_ST	Q9UQL6	HDAC5	Q15139	PRKD1	S24	L20M	20	Missense	distal	-4	no	5.200	5.203	EPSD	COSMIC	4.507	Up-regulation
CAMK_PKD_PRKD1_ST	Q9UQL6	HDAC5	Q15139	PRKD1	S24	L17F	17	Missense	distal	-7	no	5.200	5.344	EPSD	COSMIC	4.507	Up-regulation
CAMK_PKD_PRKD1_ST	Q9UQL6	HDAC5	Q15139	PRKD1	S24	E18Q	18	Missense	distal	-6	no	5.200	5.209	EPSD	COSMIC	4.507	Up-regulation
CAMK_PKD_PRKD1_ST	Q9UQL6	HDAC5	Q15139	PRKD1	S259	R255C	255	Missense	distal	-4	no	6.926	6.918	EPSD;PhosphoSitePlus	COSMIC	4.507	Down-regulation
CAMK_PKD_PRKD1_ST	Q9UQL6	HDAC5	Q15139	PRKD1	S278	R284C	284	Missense	distal	6	no	5.163	5.175	EPSD	COSMIC	4.507	Up-regulation
CAMK_PKD_PRKD1_ST	Q9UQL6	HDAC5	Q15139	PRKD1	S278	S279N	279	Missense	proximal	1	no	5.163	5.162	EPSD	COSMIC	4.507	Down-regulation
CAMK_PKD_PRKD1_ST	Q9UQL6	HDAC5	Q15139	PRKD1	S278	R284S	284	Missense	distal	6	no	5.163	5.151	EPSD	COSMIC	4.507	Down-regulation
CAMK_PKD_PRKD1_ST	Q9UQL6	HDAC5	Q15139	PRKD1	S279	R284C	284	Missense	distal	5	no	8.950	8.884	EPSD	COSMIC	4.507	Down-regulation
CAMK_PKD_PRKD1_ST	Q9UQL6	HDAC5	Q15139	PRKD1	S279	S279N	279	Missense	central	0	yes	8.950	0.000	EPSD	COSMIC	4.507	Loss
CAMK_PKD_PRKD1_ST	Q9UQL6	HDAC5	Q15139	PRKD1	S279	R284S	284	Missense	distal	5	no	8.950	8.930	EPSD	COSMIC	4.507	Down-regulation
CAMK_PKD_PRKD1_ST	Q9UQL6	HDAC5	Q15139	PRKD1	S458	R455Q	455	Missense	distal	-3	no	6.984	2.572	EPSD	COSMIC	4.507	Loss
CAMK_PKD_PRKD1_ST	Q9UQL6	HDAC5	Q15139	PRKD1	S458	R455W	455	Missense	distal	-3	no	6.984	1.612	EPSD	COSMIC	4.507	Loss
CAMK_PKD_PRKD1_ST	Q9UQL6	HDAC5	Q15139	PRKD1	S458	L460I	460	Missense	proximal	2	no	6.984	6.977	EPSD	COSMIC	4.507	Down-regulation
CAMK_PKD_PRKD1_ST	Q9UQL6	HDAC5	Q15139	PRKD1	S498	R491W	491	Missense	distal	-7	no	9.896	9.212	PhosphoSitePlus;EPSD	COSMIC	4.507	Down-regulation
CAMK_PKD_PRKD1_ST	Q9UQL6	HDAC5	Q15139	PRKD1	T546	E550D	550	Missense	distal	4	no	8.050	8.064	EPSD	COSMIC	4.507	Up-regulation
CAMK_PKD_PRKD1_ST	Q9UQL6	HDAC5	Q15139	PRKD1	S661	R658L	658	Missense	distal	-3	no	9.513	4.585	EPSD	COSMIC	4.507	Down-regulation
CAMK_PKD_PRKD1_ST	Q9UQL6	HDAC5	Q15139	PRKD1	S661	R658H	658	Missense	distal	-3	no	9.513	5.526	EPSD	COSMIC	4.507	Down-regulation
CAMK_PKD_PRKD1_ST	Q9UQL6	HDAC5	Q15139	PRKD1	S661	T659S	659	Missense	proximal	-2	no	9.513	9.829	EPSD	COSMIC	4.507	Up-regulation
CAMK_PKD_PRKD1_ST	Q9UQL6	HDAC5	Q15139	PRKD1	S713	R717H	717	Missense	distal	4	no	6.671	6.675	EPSD	COSMIC	4.507	Up-regulation
CAMK_PKD_PRKD1_ST	Q9UQL6	HDAC5	Q15139	PRKD1	S713	R710Q	710	Missense	distal	-3	no	6.671	2.258	EPSD	COSMIC	4.507	Loss
CAMK_PKD_PRKD1_ST	Q9UQL6	HDAC5	Q15139	PRKD1	S713	Q719H	719	Missense	distal	6	no	6.671	6.677	EPSD	COSMIC	4.507	Up-regulation
CAMK_PKD_PRKD1_ST	Q9UQL6	HDAC5	Q15139	PRKD1	S713	S713G	713	Missense	central	0	yes	6.671	0.000	EPSD	COSMIC	4.507	Loss
CAMK_PKD_PRKD1_ST	Q9UQL6	HDAC5	Q15139	PRKD1	S1108	E1106K	1106	Missense	proximal	-2	no	7.248	8.029	EPSD	COSMIC	4.507	Up-regulation
CAMK_PKD_PRKD1_ST	Q9UQL6	HDAC5	Q15139	PRKD1	S1108	A1104T	1104	Missense	distal	-4	no	7.248	7.243	EPSD	COSMIC;CCLE	4.507	Down-regulation
CAMK_PKD_PRKD1_ST	Q96QB1	DLC1	Q15139	PRKD1	S354	D353N	353	Missense	proximal	-1	no	5.871	5.964	EPSD	COSMIC	4.507	Up-regulation
CAMK_PKD_PRKD1_ST	Q96QB1	DLC1	Q15139	PRKD1	S354	D348E	348	Missense	distal	-6	no	5.871	5.891	EPSD	COSMIC;GDSC;CCLE	4.507	Up-regulation
CAMK_PKD_PRKD1_ST	Q96QB1	DLC1	Q15139	PRKD1	S354	S354N	354	Missense	central	0	yes	5.871	0.000	EPSD	COSMIC	4.507	Loss
CAMK_PKD_PRKD1_ST	Q96QB1	DLC1	Q15139	PRKD1	S378	G381R	381	Missense	distal	3	no	6.214	6.246	EPSD	COSMIC	4.507	Up-regulation
CAMK_PKD_PRKD1_ST	Q96QB1	DLC1	Q15139	PRKD1	S399	S397R	397	Missense	proximal	-2	no	2.888	4.733	EPSD	COSMIC	4.507	Gain
CAMK_PKD_PRKD1_ST	Q96QB1	DLC1	Q15139	PRKD1	S523	E528G	528	Missense	distal	5	no	6.164	6.077	EPSD	COSMIC	4.507	Down-regulation
CAMK_PKD_PRKD1_ST	Q96QB1	DLC1	Q15139	PRKD1	S523	D525N	525	Missense	proximal	2	no	6.164	6.210	EPSD	COSMIC	4.507	Up-regulation
CAMK_PKD_PRKD1_ST	Q96QB1	DLC1	Q15139	PRKD1	S523	R522Q	522	Missense	proximal	-1	no	6.164	6.040	EPSD	COSMIC	4.507	Down-regulation
CAMK_PKD_PRKD1_ST	Q96QB1	DLC1	Q15139	PRKD1	S523	D529N	529	Missense	distal	6	no	6.164	6.150	EPSD	COSMIC	4.507	Down-regulation
CAMK_PKD_PRKD1_ST	Q96QB1	DLC1	Q15139	PRKD1	S544	R546K	546	Missense	proximal	2	no	4.714	4.674	EPSD	COSMIC	4.507	Down-regulation
CAMK_PKD_PRKD1_ST	Q96QB1	DLC1	Q15139	PRKD1	S544	R542K	542	Missense	proximal	-2	no	4.714	3.183	EPSD	COSMIC	4.507	Loss
CAMK_PKD_PRKD1_ST	Q96QB1	DLC1	Q15139	PRKD1	S544	S544G	544	Missense	central	0	yes	4.714	0.000	EPSD	COSMIC	4.507	Loss
CAMK_PKD_PRKD1_ST	Q96QB1	DLC1	Q15139	PRKD1	S548	R546K	546	Missense	proximal	-2	no	6.637	5.106	EPSD	COSMIC	4.507	Down-regulation
CAMK_PKD_PRKD1_ST	Q96QB1	DLC1	Q15139	PRKD1	S548	E552D	552	Missense	distal	4	no	6.637	6.650	EPSD	COSMIC	4.507	Up-regulation
CAMK_PKD_PRKD1_ST	Q96QB1	DLC1	Q15139	PRKD1	S548	F553I	553	Missense	distal	5	no	6.637	6.685	EPSD	COSMIC	4.507	Up-regulation
CAMK_PKD_PRKD1_ST	Q96QB1	DLC1	Q15139	PRKD1	S548	R542K	542	Missense	distal	-6	no	6.637	6.623	EPSD	COSMIC	4.507	Down-regulation
CAMK_PKD_PRKD1_ST	Q96QB1	DLC1	Q15139	PRKD1	S548	E552K	552	Missense	distal	4	no	6.637	6.636	EPSD	COSMIC	4.507	Down-regulation
CAMK_PKD_PRKD1_ST	Q96QB1	DLC1	Q15139	PRKD1	S548	S544G	544	Missense	distal	-4	no	6.637	6.627	EPSD	COSMIC	4.507	Down-regulation
CAMK_PKD_PRKD1_ST	Q96QB1	DLC1	Q15139	PRKD1	S548	D554N	554	Missense	distal	6	no	6.637	6.622	EPSD	COSMIC	4.507	Down-regulation
CAMK_PKD_PRKD1_ST	Q96QB1	DLC1	Q15139	PRKD1	S598	L603I	603	Missense	distal	5	no	7.237	7.232	EPSD	COSMIC;CCLE	4.507	Down-regulation
CAMK_PKD_PRKD1_ST	Q96QB1	DLC1	Q15139	PRKD1	S598	S598R	598	Missense	central	0	yes	7.237	0.000	EPSD	COSMIC	4.507	Loss
CAMK_PKD_PRKD1_ST	Q96QB1	DLC1	Q15139	PRKD1	S602	S599R	599	Missense	distal	-3	no	4.465	8.902	EPSD	COSMIC	4.507	Gain
CAMK_PKD_PRKD1_ST	Q96QB1	DLC1	Q15139	PRKD1	S610	S605L	605	Missense	distal	-5	no	3.367	5.630	EPSD	COSMIC	4.507	Gain
CAMK_PKD_PRKD1_ST	Q96QB1	DLC1	Q15139	PRKD1	S620	S626F	626	Missense	distal	6	no	6.628	6.676	EPSD	COSMIC;GDSC;CCLE	4.507	Up-regulation
CAMK_PKD_PRKD1_ST	Q96QB1	DLC1	Q15139	PRKD1	S620	R617W	617	Missense	distal	-3	no	6.628	1.255	EPSD	COSMIC	4.507	Loss
CAMK_PKD_PRKD1_ST	Q96QB1	DLC1	Q15139	PRKD1	S673	S666N	666	Missense	distal	-7	no	9.600	9.272	EPSD	COSMIC	4.507	Down-regulation
CAMK_PKD_PRKD1_ST	Q96QB1	DLC1	Q15139	PRKD1	S673	R670W	670	Missense	distal	-3	no	9.600	4.227	EPSD	COSMIC	4.507	Loss
CAMK_PKD_PRKD1_ST	Q96QB1	DLC1	Q15139	PRKD1	S673	R670Q	670	Missense	distal	-3	no	9.600	5.188	EPSD	COSMIC	4.507	Down-regulation
CAMK_PKD_PRKD1_ST	Q96QB1	DLC1	Q15139	PRKD1	S733	M728V	728	Missense	distal	-5	no	8.400	8.494	EPSD	COSMIC	4.507	Up-regulation
CAMK_PKD_PRKD1_ST	Q96QB1	DLC1	Q15139	PRKD1	S733	T738M	738	Missense	distal	5	no	8.400	8.433	EPSD	COSMIC	4.507	Up-regulation
CAMK_PKD_PRKD1_ST	Q96QB1	DLC1	Q15139	PRKD1	S733	R730Q	730	Missense	distal	-3	no	8.400	3.988	EPSD	COSMIC;GDSC	4.507	Loss
CAMK_PKD_PRKD1_ST	Q96QB1	DLC1	Q15139	PRKD1	S733	R732T	732	Missense	proximal	-1	no	8.400	8.205	EPSD	COSMIC	4.507	Down-regulation
CAMK_PKD_PRKD1_ST	Q96QB1	DLC1	Q15139	PRKD1	S733	S733F	733	Missense	central	0	yes	8.400	0.000	EPSD	COSMIC	4.507	Loss
CAMK_PKD_PRKD1_ST	Q96QB1	DLC1	Q15139	PRKD1	S735	S741T	741	Missense	distal	6	no	7.891	7.922	EPSD	COSMIC	4.507	Up-regulation
CAMK_PKD_PRKD1_ST	Q96QB1	DLC1	Q15139	PRKD1	S735	M728V	728	Missense	distal	-7	no	7.891	7.620	EPSD	COSMIC	4.507	Down-regulation
CAMK_PKD_PRKD1_ST	Q96QB1	DLC1	Q15139	PRKD1	S735	T738M	738	Missense	distal	3	no	7.891	7.901	EPSD	COSMIC	4.507	Up-regulation
CAMK_PKD_PRKD1_ST	Q96QB1	DLC1	Q15139	PRKD1	S735	R730Q	730	Missense	distal	-5	no	7.891	7.177	EPSD	COSMIC;GDSC	4.507	Down-regulation
CAMK_PKD_PRKD1_ST	Q96QB1	DLC1	Q15139	PRKD1	S735	R732T	732	Missense	distal	-3	no	7.891	4.380	EPSD	COSMIC	4.507	Loss
CAMK_PKD_PRKD1_ST	Q96QB1	DLC1	Q15139	PRKD1	S735	S733F	733	Missense	proximal	-2	no	7.891	6.337	EPSD	COSMIC	4.507	Down-regulation
CAMK_PKD_PRKD1_ST	Q96QB1	DLC1	Q15139	PRKD1	S764	S757N	757	Missense	distal	-7	no	7.333	7.005	EPSD	COSMIC	4.507	Down-regulation
CAMK_PKD_PRKD1_ST	Q96QB1	DLC1	Q15139	PRKD1	S764	R763Q	763	Missense	proximal	-1	no	7.333	7.209	EPSD	COSMIC	4.507	Down-regulation
CAMK_PKD_PRKD1_ST	Q96QB1	DLC1	Q15139	PRKD1	S764	T762S	762	Missense	proximal	-2	no	7.333	7.649	EPSD	COSMIC	4.507	Up-regulation
CAMK_PKD_PRKD1_ST	Q96QB1	DLC1	Q15139	PRKD1	S764	R763W	763	Missense	proximal	-1	no	7.333	7.012	EPSD	COSMIC	4.507	Down-regulation
CAMK_PKD_PRKD1_ST	Q96QB1	DLC1	Q15139	PRKD1	S764	A767G	767	Missense	distal	3	no	7.333	7.302	EPSD	COSMIC	4.507	Down-regulation
CAMK_PKD_PRKD1_ST	Q96QB1	DLC1	Q15139	PRKD1	S766	R763Q	763	Missense	distal	-3	no	7.348	2.936	EPSD	COSMIC	4.507	Loss
CAMK_PKD_PRKD1_ST	Q96QB1	DLC1	Q15139	PRKD1	S766	T762S	762	Missense	distal	-4	no	7.348	7.353	EPSD	COSMIC	4.507	Up-regulation
CAMK_PKD_PRKD1_ST	Q96QB1	DLC1	Q15139	PRKD1	S766	R771Q	771	Missense	distal	5	no	7.348	7.325	EPSD	COSMIC	4.507	Down-regulation
CAMK_PKD_PRKD1_ST	Q96QB1	DLC1	Q15139	PRKD1	S766	R763W	763	Missense	distal	-3	no	7.348	1.975	EPSD	COSMIC	4.507	Loss
CAMK_PKD_PRKD1_ST	Q96QB1	DLC1	Q15139	PRKD1	S766	A767G	767	Missense	proximal	1	no	7.348	7.347	EPSD	COSMIC	4.507	Down-regulation
CAMK_PKD_PRKD1_ST	Q96QB1	DLC1	Q15139	PRKD1	S842	G845S	845	Missense	distal	3	no	7.280	7.305	EPSD	COSMIC	4.507	Up-regulation
CAMK_PKD_PRKD1_ST	Q96QB1	DLC1	Q15139	PRKD1	S842	T840M	840	Missense	proximal	-2	no	7.280	7.236	EPSD	COSMIC	4.507	Down-regulation
CAMK_PKD_PRKD1_ST	Q96QB1	DLC1	Q15139	PRKD1	S842	P846F	846	Missense	distal	4	no	7.280	7.296	EPSD	COSMIC	4.507	Up-regulation
CAMK_PKD_PRKD1_ST	Q96QB1	DLC1	Q15139	PRKD1	S856	R853M	853	Missense	distal	-3	no	8.730	4.608	EPSD	COSMIC	4.507	Down-regulation
CAMK_PKD_PRKD1_ST	Q96QB1	DLC1	Q15139	PRKD1	S856	N855D	855	Missense	proximal	-1	no	8.730	8.636	EPSD	COSMIC	4.507	Down-regulation
CAMK_PKD_PRKD1_ST	Q96QB1	DLC1	Q15139	PRKD1	S856	S859G	859	Missense	distal	3	no	8.730	8.705	EPSD	COSMIC	4.507	Down-regulation
CAMK_PKD_PRKD1_ST	Q96QB1	DLC1	Q15139	PRKD1	S856	E862K	862	Missense	distal	6	no	8.730	8.732	EPSD	COSMIC	4.507	Up-regulation
CAMK_PKD_PRKD1_ST	Q96QB1	DLC1	Q15139	PRKD1	S868	E862K	862	Missense	distal	-6	no	11.271	11.269	EPSD	COSMIC	4.507	Down-regulation
CAMK_PKD_PRKD1_ST	Q96QB1	DLC1	Q15139	PRKD1	S869	R875H	875	Missense	distal	6	no	5.323	5.321	EPSD	COSMIC	4.507	Down-regulation
CAMK_PKD_PRKD1_ST	Q96QB1	DLC1	Q15139	PRKD1	S869	E862K	862	Missense	distal	-7	no	5.323	5.398	EPSD	COSMIC	4.507	Up-regulation
CAMK_PKD_PRKD1_ST	Q96QB1	DLC1	Q15139	PRKD1	S871	R875H	875	Missense	distal	4	no	4.762	4.765	EPSD	COSMIC	4.507	Up-regulation
CAMK_PKD_PRKD1_ST	Q96QB1	DLC1	Q15139	PRKD1	S945	P942R	942	Missense	distal	-3	no	3.012	6.928	EPSD	COSMIC	4.507	Gain
CAMK_PKD_PRKD1_ST	Q96QB1	DLC1	Q15139	PRKD1	S986	G989V	989	Missense	distal	3	no	7.785	7.799	EPSD	COSMIC	4.507	Up-regulation
CAMK_PKD_PRKD1_ST	Q96QB1	DLC1	Q15139	PRKD1	S986	R983K	983	Missense	distal	-3	no	7.785	5.114	EPSD	COSMIC	4.507	Down-regulation
CAMK_PKD_PRKD1_ST	Q96QB1	DLC1	Q15139	PRKD1	S986	G987A	987	Missense	proximal	1	no	7.785	7.787	EPSD	COSMIC	4.507	Up-regulation
CAMK_PKD_PRKD1_ST	Q96QB1	DLC1	Q15139	PRKD1	S986	E979K	979	Missense	distal	-7	no	7.785	7.860	EPSD	COSMIC	4.507	Up-regulation
CAMK_PKD_PRKD1_ST	Q96QB1	DLC1	Q15139	PRKD1	S1004	H1009Y	1009	Missense	distal	5	no	5.932	5.827	EPSD	COSMIC	4.507	Down-regulation
CAMK_PKD_PRKD1_ST	Q96QB1	DLC1	Q15139	PRKD1	S1004	R1001Q	1001	Missense	distal	-3	no	5.932	1.520	EPSD	COSMIC	4.507	Loss
CAMK_PKD_PRKD1_ST	Q96QB1	DLC1	Q15139	PRKD1	S1004	S1004I	1004	Missense	central	0	yes	5.932	0.000	EPSD	COSMIC	4.507	Loss
CAMK_PKD_PRKD1_ST	Q96QB1	DLC1	Q15139	PRKD1	S1035	M1028I	1028	Missense	distal	-7	no	4.882	4.676	EPSD	COSMIC	4.507	Down-regulation
CAMK_PKD_PRKD1_ST	Q96QB1	DLC1	Q15139	PRKD1	S1055	G1053R	1053	Missense	proximal	-2	no	2.398	5.693	EPSD	COSMIC	4.507	Gain
CAMK_PKD_PRKD1_ST	Q96QB1	DLC1	Q15139	PRKD1	S1167	N1164K	1164	Missense	distal	-3	no	1.927	4.838	EPSD	COSMIC	4.507	Gain
CAMK_PKD_PRKD1_ST	Q96QB1	DLC1	Q15139	PRKD1	S1244	M1249I	1249	Missense	distal	5	no	8.627	8.587	PhosphoSitePlus	COSMIC	4.507	Down-regulation
CAMK_PKD_PRKD1_ST	Q96QB1	DLC1	Q15139	PRKD1	S1254	D1259Y	1259	Missense	distal	5	no	7.693	7.670	EPSD	COSMIC	4.507	Down-regulation
CAMK_PKD_PRKD1_ST	Q96QB1	DLC1	Q15139	PRKD1	S1254	M1249I	1249	Missense	distal	-5	no	7.693	7.663	EPSD	COSMIC	4.507	Down-regulation
CAMK_PKD_PRKD1_ST	Q96QB1	DLC1	Q15139	PRKD1	S1296	T1298S	1298	Missense	proximal	2	no	5.016	5.084	EPSD	COSMIC	4.507	Up-regulation
CAMK_PKD_PRKD1_ST	Q96QB1	DLC1	Q15139	PRKD1	S1296	E1289K	1289	Missense	distal	-7	no	5.016	5.091	EPSD	COSMIC	4.507	Up-regulation
CAMK_PKD_PRKD1_ST	Q96QB1	DLC1	Q15139	PRKD1	S1296	T1298A	1298	Missense	proximal	2	no	5.016	5.124	EPSD	COSMIC	4.507	Up-regulation
CAMK_PKD_PRKD1_ST	Q96QB1	DLC1	Q15139	PRKD1	S1296	N1295D	1295	Missense	proximal	-1	no	5.016	4.923	EPSD	COSMIC	4.507	Down-regulation
CAMK_PKD_PRKD1_ST	Q96QB1	DLC1	Q15139	PRKD1	S1296	T1298I	1298	Missense	proximal	2	no	5.016	4.999	EPSD	COSMIC	4.507	Down-regulation
CAMK_PKD_PRKD1_ST	Q96QB1	DLC1	Q15139	PRKD1	S1296	M1290I	1290	Missense	distal	-6	no	5.016	5.006	EPSD	COSMIC	4.507	Down-regulation
CAMK_PKD_PRKD1_ST	Q96QB1	DLC1	Q15139	PRKD1	S1296	E1289G	1289	Missense	distal	-7	no	5.016	4.688	EPSD	COSMIC	4.507	Down-regulation
CAMK_PKD_PRKD1_ST	Q96QB1	DLC1	Q15139	PRKD1	S1296	R1294S	1294	Missense	proximal	-2	no	5.016	3.172	EPSD	COSMIC	4.507	Loss
CAMK_PKD_PRKD1_ST	Q96QB1	DLC1	Q15139	PRKD1	S1296	R1292Q	1292	Missense	distal	-4	no	5.016	5.012	EPSD	COSMIC	4.507	Down-regulation
CAMK_PKD_PRKD1_ST	Q96QB1	DLC1	Q15139	PRKD1	S1355	E1353G	1353	Missense	proximal	-2	no	4.622	3.639	EPSD	COSMIC	4.507	Loss
CAMK_PKD_PRKD1_ST	Q96QB1	DLC1	Q15139	PRKD1	S1355	S1349L	1349	Missense	distal	-6	no	4.622	4.588	EPSD	COSMIC	4.507	Down-regulation
CAMK_PKD_PRKD1_ST	P16220	CREB1	Q15139	PRKD1	S98	S103N	103	Missense	distal	5	no	8.878	8.817	PhosphoSitePlus;EPSD	COSMIC	4.507	Down-regulation
CAMK_PKD_PRKD1_ST	P16220	CREB1	Q15139	PRKD1	S98	R95I	95	Missense	distal	-3	no	8.878	3.794	PhosphoSitePlus;EPSD	COSMIC	4.507	Loss
CAMK_PKD_PRKD1_ST	P16220	CREB1	Q15139	PRKD1	S98	I102M	102	Missense	distal	4	no	8.878	8.869	PhosphoSitePlus;EPSD	COSMIC	4.507	Down-regulation
CAMK_PKD_PRKD1_ST	P16220	CREB1	Q15139	PRKD1	S133	L128R	128	Missense	distal	-5	no	11.270	9.390	EPSD;PhosphoSitePlus	COSMIC	4.507	Down-regulation
CAMK_PKD_PRKD1_ST	P16220	CREB1	Q15139	PRKD1	S340	C337Y	337	Missense	distal	-3	no	4.526	2.680	EPSD	COSMIC	4.507	Loss
CAMK_PKD_PRKD1_ST	O00429	DNM1L	Q15139	PRKD1	S40	G37R	37	Missense	distal	-3	no	1.725	6.491	EPSD	COSMIC	4.507	Gain
CAMK_PKD_PRKD1_ST	O00429	DNM1L	Q15139	PRKD1	T78	R76W	76	Missense	proximal	-2	no	4.914	1.451	EPSD	COSMIC	4.507	Loss
CAMK_PKD_PRKD1_ST	O00429	DNM1L	Q15139	PRKD1	T78	T79A	79	Missense	proximal	1	no	4.914	4.915	EPSD	COSMIC	4.507	Up-regulation
CAMK_PKD_PRKD1_ST	O00429	DNM1L	Q15139	PRKD1	T79	R76W	76	Missense	distal	-3	no	5.881	0.508	EPSD	COSMIC	4.507	Loss
CAMK_PKD_PRKD1_ST	O00429	DNM1L	Q15139	PRKD1	T79	V85M	85	Missense	distal	6	no	5.881	5.869	EPSD	COSMIC	4.507	Down-regulation
CAMK_PKD_PRKD1_ST	O00429	DNM1L	Q15139	PRKD1	T79	T79A	79	Missense	central	0	yes	5.881	0.000	EPSD	COSMIC	4.507	Loss
CAMK_PKD_PRKD1_ST	O00429	DNM1L	Q15139	PRKD1	S126	G124R	124	Missense	proximal	-2	no	3.412	6.706	EPSD	COSMIC	4.507	Gain
CAMK_PKD_PRKD1_ST	O00429	DNM1L	Q15139	PRKD1	S175	P177S	177	Missense	proximal	2	no	5.588	5.631	EPSD	COSMIC	4.507	Up-regulation
CAMK_PKD_PRKD1_ST	O00429	DNM1L	Q15139	PRKD1	S175	P177T	177	Missense	proximal	2	no	5.588	5.563	EPSD	COSMIC	4.507	Down-regulation
CAMK_PKD_PRKD1_ST	O00429	DNM1L	Q15139	PRKD1	S529	D531H	531	Missense	proximal	2	no	5.617	5.721	EPSD	COSMIC	4.507	Up-regulation
CAMK_PKD_PRKD1_ST	O00429	DNM1L	Q15139	PRKD1	S529	E523D	523	Missense	distal	-6	no	5.617	5.597	EPSD	COSMIC	4.507	Down-regulation
CAMK_PKD_PRKD1_ST	O00429	DNM1L	Q15139	PRKD1	S529	S529L	529	Missense	central	0	yes	5.617	0.000	EPSD	COSMIC	4.507	Loss
CAMK_PKD_PRKD1_ST	O00429	DNM1L	Q15139	PRKD1	S529	S526L	526	Missense	distal	-3	no	5.617	5.125	EPSD	COSMIC	4.507	Down-regulation
CAMK_PKD_PRKD1_ST	O00429	DNM1L	Q15139	PRKD1	S544	A543S	543	Missense	proximal	-1	no	4.546	4.511	EPSD	COSMIC	4.507	Down-regulation
CAMK_PKD_PRKD1_ST	O00429	DNM1L	Q15139	PRKD1	S544	A539V	539	Missense	distal	-5	no	4.546	4.951	EPSD	COSMIC	4.507	Up-regulation
CAMK_PKD_PRKD1_ST	O00429	DNM1L	Q15139	PRKD1	S544	Q545K	545	Missense	proximal	1	no	4.546	4.545	EPSD	COSMIC	4.507	Down-regulation
CAMK_PKD_PRKD1_ST	O00429	DNM1L	Q15139	PRKD1	S544	S538N	538	Missense	distal	-6	no	4.546	4.528	EPSD	COSMIC	4.507	Down-regulation
CAMK_PKD_PRKD1_ST	O00429	DNM1L	Q15139	PRKD1	S548	Q545K	545	Missense	distal	-3	no	3.220	4.961	EPSD	COSMIC	4.507	Gain
CAMK_PKD_PRKD1_ST	O00429	DNM1L	Q15139	PRKD1	S607	P611L	611	Missense	distal	4	no	5.199	5.196	EPSD	COSMIC	4.507	Down-regulation
CAMK_PKD_PRKD1_ST	O00429	DNM1L	Q15139	PRKD1	S637	P631H	631	Missense	distal	-6	no	9.050	9.052	PhosphoSitePlus	COSMIC	4.507	Up-regulation
CAMK_PKD_PRKD1_ST	O00429	DNM1L	Q15139	PRKD1	S637	R634L	634	Missense	distal	-3	no	9.050	4.123	PhosphoSitePlus	COSMIC	4.507	Loss
CAMK_PKD_PRKD1_ST	O00429	DNM1L	Q15139	PRKD1	S637	R639L	639	Missense	proximal	2	no	9.050	8.961	PhosphoSitePlus	COSMIC	4.507	Down-regulation
CAMK_PKD_PRKD1_ST	O00429	DNM1L	Q15139	PRKD1	S637	R639W	639	Missense	proximal	2	no	9.050	8.902	PhosphoSitePlus	COSMIC	4.507	Down-regulation
CAMK_PKD_PRKD1_ST	Q7KZI7	MARK2	Q15139	PRKD1	S29	L24V	24	Missense	distal	-5	no	5.003	3.470	EPSD	COSMIC	4.507	Loss
CAMK_PKD_PRKD1_ST	Q7KZI7	MARK2	Q15139	PRKD1	S380	K376T	376	Missense	distal	-4	no	6.102	6.099	EPSD	COSMIC	4.507	Down-regulation
CAMK_PKD_PRKD1_ST	Q7KZI7	MARK2	Q15139	PRKD1	S380	I373L	373	Missense	distal	-7	no	6.102	5.934	EPSD	COSMIC	4.507	Down-regulation
CAMK_PKD_PRKD1_ST	Q7KZI7	MARK2	Q15139	PRKD1	S400	R407H	407	Missense	distal	7	no	7.781	7.780	PhosphoSitePlus	COSMIC	4.507	Down-regulation
CAMK_PKD_PRKD1_ST	Q7KZI7	MARK2	Q15139	PRKD1	S400	R406Q	406	Missense	distal	6	no	7.781	7.772	PhosphoSitePlus	COSMIC	4.507	Down-regulation
CAMK_PKD_PRKD1_ST	Q7KZI7	MARK2	Q15139	PRKD1	S409	R407H	407	Missense	proximal	-2	no	7.728	5.781	EPSD	COSMIC	4.507	Down-regulation
CAMK_PKD_PRKD1_ST	Q7KZI7	MARK2	Q15139	PRKD1	S409	R406Q	406	Missense	distal	-3	no	7.728	3.315	EPSD	COSMIC	4.507	Loss
CAMK_PKD_PRKD1_ST	Q7KZI7	MARK2	Q15139	PRKD1	S448	S443F	443	Missense	distal	-5	no	8.021	7.132	EPSD	COSMIC	4.507	Down-regulation
CAMK_PKD_PRKD1_ST	Q7KZI7	MARK2	Q15139	PRKD1	S448	S448N	448	Missense	central	0	yes	8.021	0.000	EPSD	COSMIC	4.507	Loss
CAMK_PKD_PRKD1_ST	Q7KZI7	MARK2	Q15139	PRKD1	S448	S449N	449	Missense	proximal	1	no	8.021	8.020	EPSD	COSMIC	4.507	Down-regulation
CAMK_PKD_PRKD1_ST	Q7KZI7	MARK2	Q15139	PRKD1	T466	P470S	470	Missense	distal	4	no	7.332	7.324	EPSD	COSMIC	4.507	Down-regulation
CAMK_PKD_PRKD1_ST	Q7KZI7	MARK2	Q15139	PRKD1	T466	E462D	462	Missense	distal	-4	no	7.332	7.325	EPSD	COSMIC	4.507	Down-regulation
CAMK_PKD_PRKD1_ST	Q7KZI7	MARK2	Q15139	PRKD1	T466	K464N	464	Missense	proximal	-2	no	7.332	5.491	EPSD	COSMIC	4.507	Down-regulation
CAMK_PKD_PRKD1_ST	Q7KZI7	MARK2	Q15139	PRKD1	S486	A492T	492	Missense	distal	6	no	4.477	4.507	EPSD	COSMIC	4.507	Gain
CAMK_PKD_PRKD1_ST	Q7KZI7	MARK2	Q15139	PRKD1	S493	A492T	492	Missense	proximal	-1	no	7.004	6.856	EPSD	COSMIC	4.507	Down-regulation
CAMK_PKD_PRKD1_ST	Q7KZI7	MARK2	Q15139	PRKD1	T515	S514F	514	Missense	proximal	-1	no	5.825	5.561	EPSD	COSMIC	4.507	Down-regulation
CAMK_PKD_PRKD1_ST	Q7KZI7	MARK2	Q15139	PRKD1	T515	A518T	518	Missense	distal	3	no	5.825	5.805	EPSD	COSMIC	4.507	Down-regulation
CAMK_PKD_PRKD1_ST	Q7KZI7	MARK2	Q15139	PRKD1	T515	G510V	510	Missense	distal	-5	no	5.825	7.307	EPSD	COSMIC	4.507	Up-regulation
CAMK_PKD_PRKD1_ST	Q7KZI7	MARK2	Q15139	PRKD1	T515	M508I	508	Missense	distal	-7	no	5.825	5.618	EPSD	COSMIC	4.507	Down-regulation
CAMK_PKD_PRKD1_ST	Q7KZI7	MARK2	Q15139	PRKD1	S519	R526W	526	Missense	distal	7	no	5.316	5.315	EPSD	COSMIC	4.507	Down-regulation
CAMK_PKD_PRKD1_ST	Q7KZI7	MARK2	Q15139	PRKD1	S519	S514F	514	Missense	distal	-5	no	5.316	4.427	EPSD	COSMIC	4.507	Loss
CAMK_PKD_PRKD1_ST	Q7KZI7	MARK2	Q15139	PRKD1	S519	A518T	518	Missense	proximal	-1	no	5.316	5.168	EPSD	COSMIC	4.507	Down-regulation
CAMK_PKD_PRKD1_ST	Q7KZI7	MARK2	Q15139	PRKD1	S523	R526W	526	Missense	distal	3	no	5.154	5.125	EPSD	COSMIC	4.507	Down-regulation
CAMK_PKD_PRKD1_ST	Q7KZI7	MARK2	Q15139	PRKD1	S523	P527S	527	Missense	distal	4	no	5.154	5.147	EPSD	COSMIC	4.507	Down-regulation
CAMK_PKD_PRKD1_ST	Q7KZI7	MARK2	Q15139	PRKD1	S523	P527Q	527	Missense	distal	4	no	5.154	5.146	EPSD	COSMIC	4.507	Down-regulation
CAMK_PKD_PRKD1_ST	Q7KZI7	MARK2	Q15139	PRKD1	S523	A518T	518	Missense	distal	-5	no	5.154	4.487	EPSD	COSMIC	4.507	Loss
CAMK_PKD_PRKD1_ST	Q7KZI7	MARK2	Q15139	PRKD1	S535	P540L	540	Missense	distal	5	no	5.216	5.205	EPSD	COSMIC	4.507	Down-regulation
CAMK_PKD_PRKD1_ST	Q7KZI7	MARK2	Q15139	PRKD1	S535	S535F	535	Missense	central	0	yes	5.216	0.000	EPSD	COSMIC	4.507	Loss
CAMK_PKD_PRKD1_ST	Q7KZI7	MARK2	Q15139	PRKD1	T560	R564H	564	Missense	distal	4	no	5.659	5.663	EPSD	COSMIC	4.507	Up-regulation
CAMK_PKD_PRKD1_ST	Q7KZI7	MARK2	Q15139	PRKD1	T560	P562S	562	Missense	proximal	2	no	5.659	5.701	EPSD	COSMIC	4.507	Up-regulation
CAMK_PKD_PRKD1_ST	Q7KZI7	MARK2	Q15139	PRKD1	T560	P566L	566	Missense	distal	6	no	5.659	5.666	EPSD	COSMIC	4.507	Up-regulation
CAMK_PKD_PRKD1_ST	Q7KZI7	MARK2	Q15139	PRKD1	T560	P562H	562	Missense	proximal	2	no	5.659	5.675	EPSD	COSMIC	4.507	Up-regulation
CAMK_PKD_PRKD1_ST	Q7KZI7	MARK2	Q15139	PRKD1	S571	P566L	566	Missense	distal	-5	no	3.381	6.226	EPSD	COSMIC	4.507	Gain
CAMK_PKD_PRKD1_ST	Q7KZI7	MARK2	Q15139	PRKD1	S592	R589H	589	Missense	distal	-3	no	4.964	0.977	EPSD	COSMIC	4.507	Loss
CAMK_PKD_PRKD1_ST	Q7KZI7	MARK2	Q15139	PRKD1	S592	P588S	588	Missense	distal	-4	no	4.964	4.967	EPSD	COSMIC	4.507	Up-regulation
CAMK_PKD_PRKD1_ST	Q7KZI7	MARK2	Q15139	PRKD1	S592	R589L	589	Missense	distal	-3	no	4.964	0.036	EPSD	COSMIC	4.507	Loss
CAMK_PKD_PRKD1_ST	Q7KZI7	MARK2	Q15139	PRKD1	S592	R589W	589	Missense	distal	-3	no	4.964	-0.409	EPSD	COSMIC	4.507	Loss
CAMK_PKD_PRKD1_ST	Q7KZI7	MARK2	Q15139	PRKD1	S592	P588L	588	Missense	distal	-4	no	4.964	4.961	EPSD	COSMIC	4.507	Down-regulation
CAMK_PKD_PRKD1_ST	Q7KZI7	MARK2	Q15139	PRKD1	S592	R594H	594	Missense	proximal	2	no	4.964	4.926	EPSD	COSMIC	4.507	Down-regulation
CAMK_PKD_PRKD1_ST	Q7KZI7	MARK2	Q15139	PRKD1	S592	R594L	594	Missense	proximal	2	no	4.964	4.875	EPSD	COSMIC	4.507	Down-regulation
CAMK_PKD_PRKD1_ST	Q7KZI7	MARK2	Q15139	PRKD1	S592	R594C	594	Missense	proximal	2	no	4.964	4.896	EPSD	COSMIC	4.507	Down-regulation
CAMK_PKD_PRKD1_ST	Q7KZI7	MARK2	Q15139	PRKD1	S621	G614S	614	Missense	distal	-7	no	4.411	4.793	EPSD	COSMIC	4.507	Gain
CAMK_PKD_PRKD1_ST	Q7KZI7	MARK2	Q15139	PRKD1	S631	R627H	627	Missense	distal	-4	no	4.800	4.794	EPSD	COSMIC	4.507	Down-regulation
CAMK_PKD_PRKD1_ST	Q7KZI7	MARK2	Q15139	PRKD1	S631	R627L	627	Missense	distal	-4	no	4.800	4.790	EPSD	COSMIC	4.507	Down-regulation
CAMK_PKD_PRKD1_ST	Q7KZI7	MARK2	Q15139	PRKD1	S631	R627C	627	Missense	distal	-4	no	4.800	4.791	EPSD	COSMIC	4.507	Down-regulation
CAMK_PKD_PRKD1_ST	Q7KZI7	MARK2	Q15139	PRKD1	S631	K637T	637	Missense	distal	6	no	4.800	4.811	EPSD	COSMIC	4.507	Up-regulation
CAMK_PKD_PRKD1_ST	Q7KZI7	MARK2	Q15139	PRKD1	S648	R654Q	654	Missense	distal	6	no	6.682	6.674	EPSD	COSMIC	4.507	Down-regulation
CAMK_PKD_PRKD1_ST	Q7KZI7	MARK2	Q15139	PRKD1	S648	K641R	641	Missense	distal	-7	no	6.682	6.943	EPSD	COSMIC	4.507	Up-regulation
CAMK_PKD_PRKD1_ST	Q7KZI7	MARK2	Q15139	PRKD1	S759	L755Q	755	Missense	distal	-4	no	4.501	4.507	EPSD	COSMIC	4.507	Gain
CAMK_PKD_PRKD1_ST	Q7KZI7	MARK2	Q15139	PRKD1	S759	G762R	762	Missense	distal	3	no	4.501	4.534	EPSD	COSMIC	4.507	Gain
CAMK_PKD_PRKD1_ST	Q7KZI7	MARK2	Q15139	PRKD1	S769	R767Q	767	Missense	proximal	-2	no	7.348	5.381	EPSD	COSMIC	4.507	Down-regulation
CAMK_PKD_PRKD1_ST	Q7KZI7	MARK2	Q15139	PRKD1	S769	G762R	762	Missense	distal	-7	no	7.348	8.011	EPSD	COSMIC	4.507	Up-regulation
CAMK_PKD_PRKD1_ST	Q15276	RABEP1	Q15139	PRKD1	S162	R158K	158	Missense	distal	-4	no	11.521	11.516	EPSD	COSMIC	4.507	Down-regulation
CAMK_PKD_PRKD1_ST	Q15276	RABEP1	Q15139	PRKD1	S229	D233A	233	Missense	distal	4	no	6.146	6.118	EPSD	COSMIC	4.507	Down-regulation
CAMK_PKD_PRKD1_ST	Q15276	RABEP1	Q15139	PRKD1	S357	S362L	362	Missense	distal	5	no	4.699	4.641	EPSD	COSMIC	4.507	Down-regulation
CAMK_PKD_PRKD1_ST	Q15276	RABEP1	Q15139	PRKD1	S374	R372C	372	Missense	proximal	-2	no	4.566	1.958	EPSD	COSMIC	4.507	Loss
CAMK_PKD_PRKD1_ST	Q15276	RABEP1	Q15139	PRKD1	S374	S374L	374	Missense	central	0	yes	4.566	0.000	EPSD	COSMIC	4.507	Loss
CAMK_PKD_PRKD1_ST	Q15276	RABEP1	Q15139	PRKD1	S447	D446A	446	Missense	proximal	-1	no	5.023	5.311	EPSD	COSMIC	4.507	Up-regulation
CAMK_PKD_PRKD1_ST	Q15276	RABEP1	Q15139	PRKD1	S766	S760P	760	Missense	distal	-6	no	6.367	6.358	EPSD	COSMIC	4.507	Down-regulation
CAMK_PKD_PRKD1_ST	O75628	REM1	Q15139	PRKD1	S18	P20T	20	Missense	proximal	2	no	10.863	10.837	PhosphoSitePlus	COSMIC	4.507	Down-regulation
CAMK_PKD_PRKD1_ST	O75628	REM1	Q15139	PRKD1	S18	T11I	11	Missense	distal	-7	no	10.863	10.675	PhosphoSitePlus	COSMIC	4.507	Down-regulation
CAMK_PKD_PRKD1_ST	O75628	REM1	Q15139	PRKD1	T19	P25S	25	Missense	distal	6	no	6.291	6.271	EPSD	COSMIC	4.507	Down-regulation
CAMK_PKD_PRKD1_ST	O75628	REM1	Q15139	PRKD1	T19	P20T	20	Missense	proximal	1	no	6.291	6.290	EPSD	COSMIC	4.507	Down-regulation
CAMK_PKD_PRKD1_ST	O75628	REM1	Q15139	PRKD1	S51	Q57K	57	Missense	distal	6	no	5.252	5.268	EPSD	COSMIC	4.507	Up-regulation
CAMK_PKD_PRKD1_ST	O75628	REM1	Q15139	PRKD1	S173	S171R	171	Missense	proximal	-2	no	3.967	5.812	EPSD	COSMIC	4.507	Gain
CAMK_PKD_PRKD1_ST	O75628	REM1	Q15139	PRKD1	S250	R248Q	248	Missense	proximal	-2	no	10.549	8.582	EPSD	COSMIC	4.507	Down-regulation
CAMK_PKD_PRKD1_ST	O75628	REM1	Q15139	PRKD1	S250	R248L	248	Missense	proximal	-2	no	10.549	7.441	EPSD	COSMIC	4.507	Down-regulation
CAMK_PKD_PRKD1_ST	O75628	REM1	Q15139	PRKD1	S250	R247H	247	Missense	distal	-3	no	10.549	6.563	EPSD	COSMIC	4.507	Down-regulation
CAMK_PKD_PRKD1_ST	O75628	REM1	Q15139	PRKD1	S250	R246H	246	Missense	distal	-4	no	10.549	10.544	EPSD	COSMIC;CCLE	4.507	Down-regulation
CAMK_PKD_PRKD1_ST	O75628	REM1	Q15139	PRKD1	S250	P255T	255	Missense	distal	5	no	10.549	10.540	EPSD	COSMIC	4.507	Down-regulation
CAMK_PKD_PRKD1_ST	O75628	REM1	Q15139	PRKD1	S250	K253N	253	Missense	distal	3	no	10.549	10.543	EPSD	COSMIC	4.507	Down-regulation
CAMK_PKD_PRKD1_ST	O75628	REM1	Q15139	PRKD1	S289	R288L	288	Missense	proximal	-1	no	5.236	5.123	EPSD	COSMIC	4.507	Down-regulation
CAMK_PKD_PRKD1_ST	O75628	REM1	Q15139	PRKD1	S289	R283W	283	Missense	distal	-6	no	5.236	5.203	EPSD	COSMIC	4.507	Down-regulation
CAMK_PKD_PRKD1_ST	O75628	REM1	Q15139	PRKD1	S289	R282H	282	Missense	distal	-7	no	5.236	4.874	EPSD	COSMIC	4.507	Down-regulation
CAMK_PKD_PRKD1_ST	O75628	REM1	Q15139	PRKD1	S289	R288C	288	Missense	proximal	-1	no	5.236	5.044	EPSD	COSMIC	4.507	Down-regulation
CAMK_PKD_PRKD1_ST	O75628	REM1	Q15139	PRKD1	S291	R288L	288	Missense	distal	-3	no	5.293	0.366	EPSD	COSMIC	4.507	Loss
CAMK_PKD_PRKD1_ST	O75628	REM1	Q15139	PRKD1	S291	R288C	288	Missense	distal	-3	no	5.293	1.196	EPSD	COSMIC	4.507	Loss
CAMK_PKD_PRKD1_ST	Q9NRA0	SPHK2	Q15139	PRKD1	S107	T102P	102	Missense	distal	-5	no	7.062	6.823	EPSD	COSMIC;GDSC;CCLE	4.507	Down-regulation
CAMK_PKD_PRKD1_ST	Q9NRA0	SPHK2	Q15139	PRKD1	S107	S105N	105	Missense	proximal	-2	no	7.062	5.536	EPSD	COSMIC	4.507	Down-regulation
CAMK_PKD_PRKD1_ST	Q9NRA0	SPHK2	Q15139	PRKD1	S107	R104W	104	Missense	distal	-3	no	7.062	1.689	EPSD	COSMIC	4.507	Loss
CAMK_PKD_PRKD1_ST	Q9NRA0	SPHK2	Q15139	PRKD1	S107	R104Q	104	Missense	distal	-3	no	7.062	2.650	EPSD	COSMIC	4.507	Loss
CAMK_PKD_PRKD1_ST	Q9NRA0	SPHK2	Q15139	PRKD1	S107	A112V	112	Missense	distal	5	no	7.062	6.980	EPSD	COSMIC;GDSC;CCLE	4.507	Down-regulation
CAMK_PKD_PRKD1_ST	Q9NRA0	SPHK2	Q15139	PRKD1	S109	T102P	102	Missense	distal	-7	no	6.868	6.924	EPSD	COSMIC;GDSC;CCLE	4.507	Up-regulation
CAMK_PKD_PRKD1_ST	Q9NRA0	SPHK2	Q15139	PRKD1	S109	S105N	105	Missense	distal	-4	no	6.868	6.860	EPSD	COSMIC	4.507	Down-regulation
CAMK_PKD_PRKD1_ST	Q9NRA0	SPHK2	Q15139	PRKD1	S109	R104W	104	Missense	distal	-5	no	6.868	6.030	EPSD	COSMIC	4.507	Down-regulation
CAMK_PKD_PRKD1_ST	Q9NRA0	SPHK2	Q15139	PRKD1	S109	R104Q	104	Missense	distal	-5	no	6.868	6.154	EPSD	COSMIC	4.507	Down-regulation
CAMK_PKD_PRKD1_ST	Q9NRA0	SPHK2	Q15139	PRKD1	S109	A112V	112	Missense	distal	3	no	6.868	6.850	EPSD	COSMIC;GDSC;CCLE	4.507	Down-regulation
CAMK_PKD_PRKD1_ST	Q9NRA0	SPHK2	Q15139	PRKD1	S399	S399L	399	Missense	central	0	yes	9.452	0.000	EPSD	COSMIC	4.507	Loss
CAMK_PKD_PRKD1_ST	Q9NRA0	SPHK2	Q15139	PRKD1	S399	R396H	396	Missense	distal	-3	no	9.452	5.465	EPSD	COSMIC	4.507	Down-regulation
CAMK_PKD_PRKD1_ST	Q9NRA0	SPHK2	Q15139	PRKD1	S399	A397T	397	Missense	proximal	-2	no	9.452	8.845	EPSD	COSMIC	4.507	Down-regulation
CAMK_PKD_PRKD1_ST	Q9NRA0	SPHK2	Q15139	PRKD1	S399	P405Q	405	Missense	distal	6	no	9.452	9.436	EPSD	COSMIC	4.507	Down-regulation
CAMK_PKD_PRKD1_ST	Q9NRA0	SPHK2	Q15139	PRKD1	S399	P405L	405	Missense	distal	6	no	9.452	9.459	EPSD	COSMIC	4.507	Up-regulation
CAMK_PKD_PRKD1_ST	Q9NRA0	SPHK2	Q15139	PRKD1	S399	P405S	405	Missense	distal	6	no	9.452	9.432	EPSD	COSMIC	4.507	Down-regulation
CAMK_PKD_PRKD1_ST	Q9NRA0	SPHK2	Q15139	PRKD1	S421	S419F	419	Missense	proximal	-2	no	8.102	6.548	PhosphoSitePlus;EPSD	COSMIC	4.507	Down-regulation
CAMK_PKD_PRKD1_ST	Q9NRA0	SPHK2	Q15139	PRKD1	S421	H417N	417	Missense	distal	-4	no	8.102	8.097	PhosphoSitePlus;EPSD	COSMIC	4.507	Down-regulation
CAMK_PKD_PRKD1_ST	Q9NRA0	SPHK2	Q15139	PRKD1	S421	R418C	418	Missense	distal	-3	no	8.102	4.005	PhosphoSitePlus;EPSD	COSMIC	4.507	Loss
CAMK_PKD_PRKD1_ST	Q9NRA0	SPHK2	Q15139	PRKD1	S421	D422E	422	Missense	proximal	1	no	8.102	8.103	PhosphoSitePlus;EPSD	COSMIC	4.507	Up-regulation
CAMK_PKD_PRKD1_ST	Q9NRA0	SPHK2	Q15139	PRKD1	S421	P424S	424	Missense	distal	3	no	8.102	8.113	PhosphoSitePlus;EPSD	COSMIC	4.507	Up-regulation
CAMK_PKD_PRKD1_ST	Q9NRA0	SPHK2	Q15139	PRKD1	S487	V492I	492	Missense	distal	5	no	5.505	5.502	EPSD	COSMIC	4.507	Down-regulation
CAMK_PKD_PRKD1_ST	Q99683	MAP3K5	Q15139	PRKD1	S83	G81S	81	Missense	proximal	-2	no	4.917	6.367	EPSD	COSMIC	4.507	Up-regulation
CAMK_PKD_PRKD1_ST	Q99683	MAP3K5	Q15139	PRKD1	S83	G87S	87	Missense	distal	4	no	4.917	4.891	EPSD	COSMIC	4.507	Down-regulation
CAMK_PKD_PRKD1_ST	Q99683	MAP3K5	Q15139	PRKD1	S719	Q720E	720	Missense	proximal	1	no	5.470	5.469	EPSD	COSMIC	4.507	Down-regulation
CAMK_PKD_PRKD1_ST	Q99683	MAP3K5	Q15139	PRKD1	S719	R714K	714	Missense	distal	-5	no	5.470	4.447	EPSD	COSMIC	4.507	Loss
CAMK_PKD_PRKD1_ST	Q99683	MAP3K5	Q15139	PRKD1	S763	P758L	758	Missense	distal	-5	no	2.938	5.784	EPSD	COSMIC	4.507	Gain
CAMK_PKD_PRKD1_ST	Q99683	MAP3K5	Q15139	PRKD1	S966	V969I	969	Missense	distal	3	no	5.837	5.836	EPSD	COSMIC	4.507	Down-regulation
CAMK_PKD_PRKD1_ST	Q99683	MAP3K5	Q15139	PRKD1	T1015	G1012R	1012	Missense	distal	-3	no	0.733	5.499	EPSD	COSMIC	4.507	Gain
CAMK_PKD_PRKD1_ST	Q99683	MAP3K5	Q15139	PRKD1	T1059	A1052T	1052	Missense	distal	-7	no	6.060	5.800	EPSD	COSMIC	4.507	Down-regulation
CAMK_PKD_PRKD1_ST	O96013	PAK4	Q15139	PRKD1	S99	R96H	96	Missense	distal	-3	no	8.722	4.735	PhosphoSitePlus	COSMIC	4.507	Down-regulation
CAMK_PKD_PRKD1_ST	O96013	PAK4	Q15139	PRKD1	S99	S93F	93	Missense	distal	-6	no	8.722	8.694	PhosphoSitePlus	COSMIC	4.507	Down-regulation
CAMK_PKD_PRKD1_ST	O96013	PAK4	Q15139	PRKD1	S99	R101Q	101	Missense	proximal	2	no	8.722	8.705	PhosphoSitePlus	COSMIC	4.507	Down-regulation
CAMK_PKD_PRKD1_ST	O96013	PAK4	Q15139	PRKD1	S104	A109T	109	Missense	distal	5	no	9.929	9.852	EPSD	COSMIC	4.507	Down-regulation
CAMK_PKD_PRKD1_ST	O96013	PAK4	Q15139	PRKD1	S104	P106S	106	Missense	proximal	2	no	9.929	9.971	EPSD	COSMIC	4.507	Up-regulation
CAMK_PKD_PRKD1_ST	O96013	PAK4	Q15139	PRKD1	S104	R101Q	101	Missense	distal	-3	no	9.929	5.517	EPSD	COSMIC	4.507	Down-regulation
CAMK_PKD_PRKD1_ST	O96013	PAK4	Q15139	PRKD1	S162	R164Q	164	Missense	proximal	2	no	6.401	6.384	EPSD	COSMIC	4.507	Down-regulation
CAMK_PKD_PRKD1_ST	O96013	PAK4	Q15139	PRKD1	S167	R164Q	164	Missense	distal	-3	no	5.995	1.583	EPSD	COSMIC	4.507	Loss
CAMK_PKD_PRKD1_ST	O96013	PAK4	Q15139	PRKD1	S181	G182R	182	Missense	proximal	1	no	6.506	6.507	EPSD	COSMIC	4.507	Up-regulation
CAMK_PKD_PRKD1_ST	O96013	PAK4	Q15139	PRKD1	S181	R175W	175	Missense	distal	-6	no	6.506	6.473	EPSD	COSMIC	4.507	Down-regulation
CAMK_PKD_PRKD1_ST	O96013	PAK4	Q15139	PRKD1	S181	P179L	179	Missense	proximal	-2	no	6.506	5.564	EPSD	COSMIC	4.507	Down-regulation
CAMK_PKD_PRKD1_ST	O96013	PAK4	Q15139	PRKD1	S181	P183S	183	Missense	proximal	2	no	6.506	6.548	EPSD	COSMIC	4.507	Up-regulation
CAMK_PKD_PRKD1_ST	O96013	PAK4	Q15139	PRKD1	T213	P216T	216	Missense	distal	3	no	4.657	4.654	EPSD	COSMIC	4.507	Down-regulation
CAMK_PKD_PRKD1_ST	O96013	PAK4	Q15139	PRKD1	S243	R248Q	248	Missense	distal	5	no	4.809	4.786	EPSD	COSMIC	4.507	Down-regulation
CAMK_PKD_PRKD1_ST	O96013	PAK4	Q15139	PRKD1	S243	A238S	238	Missense	distal	-5	no	4.809	4.484	EPSD	COSMIC	4.507	Loss
CAMK_PKD_PRKD1_ST	O96013	PAK4	Q15139	PRKD1	T251	R252Q	252	Missense	proximal	1	no	5.212	5.213	EPSD	COSMIC;GDSC;CCLE	4.507	Up-regulation
CAMK_PKD_PRKD1_ST	O96013	PAK4	Q15139	PRKD1	T251	A256D	256	Missense	distal	5	no	5.212	5.092	EPSD	COSMIC	4.507	Down-regulation
CAMK_PKD_PRKD1_ST	O96013	PAK4	Q15139	PRKD1	T251	R248Q	248	Missense	distal	-3	no	5.212	0.800	EPSD	COSMIC	4.507	Loss
CAMK_PKD_PRKD1_ST	O96013	PAK4	Q15139	PRKD1	S474	R471Q	471	Missense	distal	-3	no	11.240	6.827	EPSD	COSMIC	4.507	Down-regulation
CAMK_PKD_PRKD1_ST	O96013	PAK4	Q15139	PRKD1	S474	P479S	479	Missense	distal	5	no	11.240	11.286	EPSD	COSMIC	4.507	Up-regulation
CAMK_PKD_PRKD1_ST	O96013	PAK4	Q15139	PRKD1	S474	G477D	477	Missense	distal	3	no	11.240	11.239	EPSD	COSMIC	4.507	Down-regulation
CAMK_PKD_PRKD1_ST	P27986	PIK3R1	Q15139	PRKD1	S83	P85S	85	Missense	proximal	2	no	5.137	5.179	EPSD	COSMIC	4.507	Up-regulation
CAMK_PKD_PRKD1_ST	P27986	PIK3R1	Q15139	PRKD1	S83	P84L	84	Missense	proximal	1	no	5.137	5.136	EPSD	COSMIC	4.507	Down-regulation
CAMK_PKD_PRKD1_ST	P27986	PIK3R1	Q15139	PRKD1	S154	L149I	149	Missense	distal	-5	no	9.099	7.442	PhosphoSitePlus	COSMIC	4.507	Down-regulation
CAMK_PKD_PRKD1_ST	P27986	PIK3R1	Q15139	PRKD1	S154	L149S	149	Missense	distal	-5	no	9.099	6.835	PhosphoSitePlus	COSMIC	4.507	Down-regulation
CAMK_PKD_PRKD1_ST	P27986	PIK3R1	Q15139	PRKD1	S154	T148I	148	Missense	distal	-6	no	9.099	9.094	PhosphoSitePlus	COSMIC	4.507	Down-regulation
CAMK_PKD_PRKD1_ST	P27986	PIK3R1	Q15139	PRKD1	S154	N157H	157	Missense	distal	3	no	9.099	9.111	PhosphoSitePlus	COSMIC	4.507	Up-regulation
CAMK_PKD_PRKD1_ST	P27986	PIK3R1	Q15139	PRKD1	S265	R262P	262	Missense	distal	-3	no	4.833	0.917	EPSD	COSMIC	4.507	Loss
CAMK_PKD_PRKD1_ST	P27986	PIK3R1	Q15139	PRKD1	S265	R262C	262	Missense	distal	-3	no	4.833	0.736	EPSD	COSMIC	4.507	Loss
CAMK_PKD_PRKD1_ST	P27986	PIK3R1	Q15139	PRKD1	S265	S265R	265	Missense	central	0	yes	4.833	0.000	EPSD	COSMIC	4.507	Loss
CAMK_PKD_PRKD1_ST	P27986	PIK3R1	Q15139	PRKD1	S265	S265N	265	Missense	central	0	yes	4.833	0.000	EPSD	COSMIC	4.507	Loss
CAMK_PKD_PRKD1_ST	P27986	PIK3R1	Q15139	PRKD1	S265	S265I	265	Missense	central	0	yes	4.833	0.000	EPSD	COSMIC	4.507	Loss
CAMK_PKD_PRKD1_ST	P27986	PIK3R1	Q15139	PRKD1	S265	N260S	260	Missense	distal	-5	no	4.833	4.673	EPSD	COSMIC;GDSC;CCLE	4.507	Down-regulation
CAMK_PKD_PRKD1_ST	P27986	PIK3R1	Q15139	PRKD1	S265	R262G	262	Missense	distal	-3	no	4.833	0.066	EPSD	COSMIC	4.507	Loss
CAMK_PKD_PRKD1_ST	P27986	PIK3R1	Q15139	PRKD1	S265	F268L	268	Missense	distal	3	no	4.833	4.849	EPSD	COSMIC	4.507	Up-regulation
CAMK_PKD_PRKD1_ST	P27986	PIK3R1	Q15139	PRKD1	S265	F268C	268	Missense	distal	3	no	4.833	4.850	EPSD	COSMIC	4.507	Up-regulation
CAMK_PKD_PRKD1_ST	P27986	PIK3R1	Q15139	PRKD1	S269	R274K	274	Missense	distal	5	no	4.783	4.728	EPSD	COSMIC	4.507	Down-regulation
CAMK_PKD_PRKD1_ST	P27986	PIK3R1	Q15139	PRKD1	S269	R274T	274	Missense	distal	5	no	4.783	4.708	EPSD	COSMIC	4.507	Down-regulation
CAMK_PKD_PRKD1_ST	P27986	PIK3R1	Q15139	PRKD1	S269	R262P	262	Missense	distal	-7	no	4.783	4.391	EPSD	COSMIC	4.507	Loss
CAMK_PKD_PRKD1_ST	P27986	PIK3R1	Q15139	PRKD1	S269	R262C	262	Missense	distal	-7	no	4.783	4.330	EPSD	COSMIC	4.507	Loss
CAMK_PKD_PRKD1_ST	P27986	PIK3R1	Q15139	PRKD1	S269	R274S	274	Missense	distal	5	no	4.783	4.764	EPSD	COSMIC	4.507	Down-regulation
CAMK_PKD_PRKD1_ST	P27986	PIK3R1	Q15139	PRKD1	S269	S265R	265	Missense	distal	-4	no	4.783	4.787	EPSD	COSMIC	4.507	Up-regulation
CAMK_PKD_PRKD1_ST	P27986	PIK3R1	Q15139	PRKD1	S269	S265N	265	Missense	distal	-4	no	4.783	4.776	EPSD	COSMIC	4.507	Down-regulation
CAMK_PKD_PRKD1_ST	P27986	PIK3R1	Q15139	PRKD1	S269	R274G	274	Missense	distal	5	no	4.783	4.640	EPSD	COSMIC	4.507	Down-regulation
CAMK_PKD_PRKD1_ST	P27986	PIK3R1	Q15139	PRKD1	S269	R274I	274	Missense	distal	5	no	4.783	4.701	EPSD	COSMIC	4.507	Down-regulation
CAMK_PKD_PRKD1_ST	P27986	PIK3R1	Q15139	PRKD1	S269	S265I	265	Missense	distal	-4	no	4.783	4.776	EPSD	COSMIC	4.507	Down-regulation
CAMK_PKD_PRKD1_ST	P27986	PIK3R1	Q15139	PRKD1	S269	R262G	262	Missense	distal	-7	no	4.783	4.120	EPSD	COSMIC	4.507	Loss
CAMK_PKD_PRKD1_ST	P27986	PIK3R1	Q15139	PRKD1	S269	L272F	272	Missense	distal	3	no	4.783	4.767	EPSD	COSMIC	4.507	Down-regulation
CAMK_PKD_PRKD1_ST	P27986	PIK3R1	Q15139	PRKD1	S269	F268L	268	Missense	proximal	-1	no	4.783	5.015	EPSD	COSMIC	4.507	Up-regulation
CAMK_PKD_PRKD1_ST	P27986	PIK3R1	Q15139	PRKD1	S269	F268C	268	Missense	proximal	-1	no	4.783	4.936	EPSD	COSMIC	4.507	Up-regulation
CAMK_PKD_PRKD1_ST	P27986	PIK3R1	Q15139	PRKD1	S651	F646L	646	Missense	distal	-5	no	2.046	5.198	EPSD	COSMIC	4.507	Gain
CAMK_PKD_PRKD1_ST	P27986	PIK3R1	Q15139	PRKD1	S652	L647V	647	Missense	distal	-5	no	9.404	7.871	EPSD	COSMIC	4.507	Down-regulation
CAMK_PKD_PRKD1_ST	P27986	PIK3R1	Q15139	PRKD1	S652	R649Q	649	Missense	distal	-3	no	9.404	4.992	EPSD	COSMIC	4.507	Down-regulation
CAMK_PKD_PRKD1_ST	P27986	PIK3R1	Q15139	PRKD1	S652	R649W	649	Missense	distal	-3	no	9.404	4.032	EPSD	COSMIC	4.507	Loss
CAMK_PKD_PRKD1_ST	P27986	PIK3R1	Q15139	PRKD1	S652	L647F	647	Missense	distal	-5	no	9.404	6.253	EPSD	COSMIC	4.507	Down-regulation
CAMK_PKD_PRKD1_ST	P27986	PIK3R1	Q15139	PRKD1	S652	F646L	646	Missense	distal	-6	no	9.404	9.400	EPSD	COSMIC	4.507	Down-regulation
CAMK_PKD_PRKD1_ST	P27986	PIK3R1	Q15139	PRKD1	S652	L647I	647	Missense	distal	-5	no	9.404	7.748	EPSD	COSMIC	4.507	Down-regulation
CAMK_PKD_PRKD1_ST	P31749	AKT1	Q15139	PRKD1	T65	L62R	62	Missense	distal	-3	no	0.380	5.308	EPSD	COSMIC	4.507	Gain
CAMK_PKD_PRKD1_ST	P31749	AKT1	Q15139	PRKD1	T72	C77F	77	Missense	distal	5	no	4.787	4.722	EPSD	COSMIC	4.507	Down-regulation
CAMK_PKD_PRKD1_ST	P31749	AKT1	Q15139	PRKD1	T72	R67Q	67	Missense	distal	-5	no	4.787	4.073	EPSD	COSMIC	4.507	Loss
CAMK_PKD_PRKD1_ST	P31749	AKT1	Q15139	PRKD1	T72	R76H	76	Missense	distal	4	no	4.787	4.791	EPSD	COSMIC	4.507	Up-regulation
CAMK_PKD_PRKD1_ST	P31749	AKT1	Q15139	PRKD1	T72	R69L	69	Missense	distal	-3	no	4.787	-0.141	EPSD	COSMIC	4.507	Loss
CAMK_PKD_PRKD1_ST	P31749	AKT1	Q15139	PRKD1	T72	P70L	70	Missense	proximal	-2	no	4.787	3.845	EPSD	COSMIC	4.507	Loss
CAMK_PKD_PRKD1_ST	P31749	AKT1	Q15139	PRKD1	S124	G123D	123	Missense	proximal	-1	no	6.544	6.551	EPSD	COSMIC	4.507	Up-regulation
CAMK_PKD_PRKD1_ST	P31749	AKT1	Q15139	PRKD1	S124	D127N	127	Missense	distal	3	no	6.544	6.556	EPSD	COSMIC	4.507	Up-regulation
CAMK_PKD_PRKD1_ST	P31749	AKT1	Q15139	PRKD1	S124	G130R	130	Missense	distal	6	no	6.544	6.504	EPSD	COSMIC	4.507	Down-regulation
CAMK_PKD_PRKD1_ST	P31749	AKT1	Q15139	PRKD1	S246	S240P	240	Missense	distal	-6	no	6.314	6.305	EPSD	COSMIC	4.507	Down-regulation
CAMK_PKD_PRKD1_ST	P31749	AKT1	Q15139	PRKD1	S246	A250V	250	Missense	distal	4	no	6.314	6.329	EPSD	COSMIC	4.507	Up-regulation
CAMK_PKD_PRKD1_ST	P31749	AKT1	Q15139	PRKD1	S246	R243H	243	Missense	distal	-3	no	6.314	2.327	EPSD	COSMIC	4.507	Loss
CAMK_PKD_PRKD1_ST	P31749	AKT1	Q15139	PRKD1	S246	S240C	240	Missense	distal	-6	no	6.314	6.300	EPSD	COSMIC	4.507	Down-regulation
CAMK_PKD_PRKD1_ST	P31749	AKT1	Q15139	PRKD1	S422	V416M	416	Missense	distal	-6	no	5.041	5.050	EPSD	COSMIC	4.507	Up-regulation
CAMK_PKD_PRKD1_ST	P31749	AKT1	Q15139	PRKD1	S422	S422R	422	Missense	central	0	yes	5.041	0.000	EPSD	COSMIC	4.507	Loss
CAMK_PKD_PRKD1_ST	Q96A00	PPP1R14A	Q15139	PRKD1	S16	A20T	20	Missense	distal	4	no	6.215	6.236	EPSD	COSMIC	4.507	Up-regulation
CAMK_PKD_PRKD1_ST	Q96A00	PPP1R14A	Q15139	PRKD1	S16	P23A	23	Missense	distal	7	no	6.215	6.216	EPSD	COSMIC	4.507	Up-regulation
CAMK_PKD_PRKD1_ST	Q96A00	PPP1R14A	Q15139	PRKD1	T38	D42N	42	Missense	distal	4	no	6.887	6.877	PhosphoSitePlus	COSMIC	4.507	Down-regulation
CAMK_PKD_PRKD1_ST	Q96A00	PPP1R14A	Q15139	PRKD1	S128	P122L	122	Missense	distal	-6	no	6.096	6.072	EPSD	COSMIC	4.507	Down-regulation
CAMK_PKD_PRKD1_ST	Q14896	MYBPC3	Q15139	PRKD1	S275	R272H	272	Missense	distal	-3	no	9.937	5.950	EPSD	COSMIC	4.507	Down-regulation
CAMK_PKD_PRKD1_ST	Q14896	MYBPC3	Q15139	PRKD1	S304	R306W	306	Missense	proximal	2	no	10.158	10.010	PhosphoSitePlus	COSMIC	4.507	Down-regulation
CAMK_PKD_PRKD1_ST	Q14896	MYBPC3	Q15139	PRKD1	S304	S311L	311	Missense	distal	7	no	10.158	10.157	PhosphoSitePlus	COSMIC	4.507	Down-regulation
CAMK_PKD_PRKD1_ST	Q14896	MYBPC3	Q15139	PRKD1	S304	D303Y	303	Missense	proximal	-1	no	10.158	10.110	PhosphoSitePlus	COSMIC	4.507	Down-regulation
CAMK_PKD_PRKD1_ST	Q14896	MYBPC3	Q15139	PRKD1	S311	P316S	316	Missense	distal	5	no	4.851	4.897	EPSD	COSMIC;GDSC;CCLE	4.507	Up-regulation
CAMK_PKD_PRKD1_ST	Q14896	MYBPC3	Q15139	PRKD1	S311	R306W	306	Missense	distal	-5	no	4.851	4.014	EPSD	COSMIC	4.507	Loss
CAMK_PKD_PRKD1_ST	Q14896	MYBPC3	Q15139	PRKD1	S311	S311L	311	Missense	central	0	yes	4.851	0.000	EPSD	COSMIC	4.507	Loss
CAMK_PKD_PRKD1_ST	Q14896	MYBPC3	Q15139	PRKD1	S311	F305L	305	Missense	distal	-6	no	4.851	4.846	EPSD	COSMIC	4.507	Down-regulation
CAMK_PKD_PRKD1_ST	Q14896	MYBPC3	Q15139	PRKD1	S830	F823L	823	Missense	distal	-7	no	5.021	4.877	EPSD	COSMIC;GDSC;CCLE	4.507	Down-regulation
CAMK_PKD_PRKD1_ST	O60331	PIP5K1C	Q15139	PRKD1	S448	T442M	442	Missense	distal	-6	no	7.969	7.975	PhosphoSitePlus	COSMIC;CCLE	4.507	Up-regulation
CAMK_PKD_PRKD1_ST	O60331	PIP5K1C	Q15139	PRKD1	S448	S448F	448	Missense	central	0	yes	7.969	0.000	PhosphoSitePlus	COSMIC	4.507	Loss
CAMK_PKD_PRKD1_ST	O60331	PIP5K1C	Q15139	PRKD1	S455	G460S	460	Missense	distal	5	no	4.692	4.816	EPSD	COSMIC	4.507	Up-regulation
CAMK_PKD_PRKD1_ST	O60331	PIP5K1C	Q15139	PRKD1	S455	G460C	460	Missense	distal	5	no	4.692	4.770	EPSD	COSMIC	4.507	Up-regulation
CAMK_PKD_PRKD1_ST	O60331	PIP5K1C	Q15139	PRKD1	S455	S448F	448	Missense	distal	-7	no	4.692	4.312	EPSD	COSMIC	4.507	Loss
CAMK_PKD_PRKD1_ST	O60331	PIP5K1C	Q15139	PRKD1	S496	R495H	495	Missense	proximal	-1	no	4.536	4.423	EPSD	COSMIC	4.507	Loss
CAMK_PKD_PRKD1_ST	O60331	PIP5K1C	Q15139	PRKD1	S496	E501Q	501	Missense	distal	5	no	4.536	4.569	EPSD	COSMIC	4.507	Up-regulation
CAMK_PKD_PRKD1_ST	O60331	PIP5K1C	Q15139	PRKD1	S496	D490N	490	Missense	distal	-6	no	4.536	4.544	EPSD	COSMIC	4.507	Up-regulation
CAMK_PKD_PRKD1_ST	O60331	PIP5K1C	Q15139	PRKD1	S496	L500V	500	Missense	distal	4	no	4.536	4.539	EPSD	COSMIC;GDSC;CCLE	4.507	Up-regulation
CAMK_PKD_PRKD1_ST	O60331	PIP5K1C	Q15139	PRKD1	S541	R538L	538	Missense	distal	-3	no	7.574	2.647	EPSD	COSMIC	4.507	Loss
CAMK_PKD_PRKD1_ST	O60331	PIP5K1C	Q15139	PRKD1	T553	R552G	552	Missense	proximal	-1	no	8.040	7.699	EPSD	COSMIC	4.507	Down-regulation
CAMK_PKD_PRKD1_ST	O60331	PIP5K1C	Q15139	PRKD1	T553	R552C	552	Missense	proximal	-1	no	8.040	7.848	EPSD	COSMIC;GDSC;CCLE	4.507	Down-regulation
CAMK_PKD_PRKD1_ST	O60331	PIP5K1C	Q15139	PRKD1	T553	R552L	552	Missense	proximal	-1	no	8.040	7.926	EPSD	COSMIC	4.507	Down-regulation
CAMK_PKD_PRKD1_ST	O60331	PIP5K1C	Q15139	PRKD1	S555	R552G	552	Missense	distal	-3	no	7.198	2.431	EPSD	COSMIC	4.507	Loss
CAMK_PKD_PRKD1_ST	O60331	PIP5K1C	Q15139	PRKD1	S555	R552C	552	Missense	distal	-3	no	7.198	3.100	EPSD	COSMIC;GDSC;CCLE	4.507	Loss
CAMK_PKD_PRKD1_ST	O60331	PIP5K1C	Q15139	PRKD1	S555	R552L	552	Missense	distal	-3	no	7.198	2.270	EPSD	COSMIC	4.507	Loss
CAMK_PKD_PRKD1_ST	Q15139	PRKD1	Q15139	PRKD1	S205	R201Q	201	Missense	distal	-4	no	10.262	10.257	EPSD	COSMIC;GDSC;CCLE	4.507	Down-regulation
CAMK_PKD_PRKD1_ST	Q15139	PRKD1	Q15139	PRKD1	S205	R200K	200	Missense	distal	-5	no	10.262	9.238	EPSD	COSMIC	4.507	Down-regulation
CAMK_PKD_PRKD1_ST	Q15139	PRKD1	Q15139	PRKD1	S223	P227S	227	Missense	distal	4	no	4.978	4.970	EPSD	COSMIC	4.507	Down-regulation
CAMK_PKD_PRKD1_ST	Q15139	PRKD1	Q15139	PRKD1	S237	S239L	239	Missense	proximal	2	no	7.026	6.948	EPSD	COSMIC	4.507	Down-regulation
CAMK_PKD_PRKD1_ST	Q15139	PRKD1	Q15139	PRKD1	S249	K245N	245	Missense	distal	-4	no	5.773	5.767	EPSD	COSMIC	4.507	Down-regulation
CAMK_PKD_PRKD1_ST	Q15139	PRKD1	Q15139	PRKD1	S249	S251L	251	Missense	proximal	2	no	5.773	5.696	EPSD	COSMIC	4.507	Down-regulation
CAMK_PKD_PRKD1_ST	Q15139	PRKD1	Q15139	PRKD1	S397	R394K	394	Missense	distal	-3	no	7.330	4.658	EPSD	COSMIC	4.507	Down-regulation
CAMK_PKD_PRKD1_ST	Q15139	PRKD1	Q15139	PRKD1	S397	S397N	397	Missense	central	0	yes	7.330	0.000	EPSD	COSMIC	4.507	Loss
CAMK_PKD_PRKD1_ST	Q15139	PRKD1	Q15139	PRKD1	S397	N402T	402	Missense	distal	5	no	7.330	7.335	EPSD	COSMIC	4.507	Up-regulation
CAMK_PKD_PRKD1_ST	Q15139	PRKD1	Q15139	PRKD1	S420	V413D	413	Missense	distal	-7	no	6.150	6.128	EPSD	COSMIC	4.507	Down-regulation
CAMK_PKD_PRKD1_ST	Q15139	PRKD1	Q15139	PRKD1	S420	S420F	420	Missense	central	0	yes	6.150	0.000	EPSD	COSMIC	4.507	Loss
CAMK_PKD_PRKD1_ST	Q15139	PRKD1	Q15139	PRKD1	S421	S420F	420	Missense	proximal	-1	no	6.747	6.483	EPSD	COSMIC	4.507	Down-regulation
CAMK_PKD_PRKD1_ST	Q15139	PRKD1	Q15139	PRKD1	T458	Q455R	455	Missense	distal	-3	no	1.740	6.153	EPSD	COSMIC	4.507	Gain
CAMK_PKD_PRKD1_ST	Q15139	PRKD1	Q15139	PRKD1	S549	P542R	542	Missense	distal	-7	no	4.350	4.743	EPSD	COSMIC	4.507	Gain
CAMK_PKD_PRKD1_ST	Q15139	PRKD1	Q15139	PRKD1	S742	A748T	748	Missense	distal	6	no	5.218	5.249	EPSD;PhosphoSitePlus	COSMIC	4.507	Up-regulation
CAMK_PKD_PRKD1_ST	Q15139	PRKD1	Q15139	PRKD1	S742	G735V	735	Missense	distal	-7	no	5.218	5.180	EPSD;PhosphoSitePlus	COSMIC	4.507	Down-regulation
CAMK_PKD_PRKD1_ST	Q15139	PRKD1	Q15139	PRKD1	S742	T746I	746	Missense	distal	4	no	5.218	5.215	EPSD;PhosphoSitePlus	COSMIC	4.507	Down-regulation
CAMK_PKD_PRKD1_ST	Q15139	PRKD1	Q15139	PRKD1	S829	Y828H	828	Missense	proximal	-1	no	7.429	7.697	EPSD	COSMIC	4.507	Up-regulation
CAMK_PKD_PRKD1_ST	Q15139	PRKD1	Q15139	PRKD1	S910	V909D	909	Missense	proximal	-1	no	7.394	7.285	EPSD;PhosphoSitePlus	COSMIC	4.507	Down-regulation
CAMK_PKD_PRKD1_ST	Q13936	CACNA1C	Q15139	PRKD1	S465	P467L	467	Missense	proximal	2	no	6.235	6.199	EPSD	COSMIC	4.507	Down-regulation
CAMK_PKD_PRKD1_ST	Q13936	CACNA1C	Q15139	PRKD1	S863	L867F	867	Missense	distal	4	no	7.174	7.193	EPSD	COSMIC	4.507	Up-regulation
CAMK_PKD_PRKD1_ST	Q13936	CACNA1C	Q15139	PRKD1	S863	R858S	858	Missense	distal	-5	no	7.174	6.790	EPSD	COSMIC	4.507	Down-regulation
CAMK_PKD_PRKD1_ST	Q13936	CACNA1C	Q15139	PRKD1	S863	S863F	863	Missense	central	0	yes	7.174	0.000	EPSD	COSMIC	4.507	Loss
CAMK_PKD_PRKD1_ST	Q13936	CACNA1C	Q15139	PRKD1	S1535	G1538S	1538	Missense	distal	3	no	7.690	7.715	EPSD	COSMIC	4.507	Up-regulation
CAMK_PKD_PRKD1_ST	Q13936	CACNA1C	Q15139	PRKD1	S1535	P1539L	1539	Missense	distal	4	no	7.690	7.687	EPSD	COSMIC	4.507	Down-regulation
CAMK_PKD_PRKD1_ST	Q13936	CACNA1C	Q15139	PRKD1	S1535	H1540Q	1540	Missense	distal	5	no	7.690	7.703	EPSD	COSMIC	4.507	Up-regulation
CAMK_PKD_PRKD1_ST	Q13936	CACNA1C	Q15139	PRKD1	S1645	K1638N	1638	Missense	distal	-7	no	8.255	7.907	EPSD	COSMIC	4.507	Down-regulation
CAMK_PKD_PRKD1_ST	Q13936	CACNA1C	Q15139	PRKD1	S1645	K1642N	1642	Missense	distal	-3	no	8.255	5.344	EPSD	COSMIC	4.507	Down-regulation
CAMK_PKD_PRKD1_ST	Q13936	CACNA1C	Q15139	PRKD1	S1645	Q1651K	1651	Missense	distal	6	no	8.255	8.271	EPSD	COSMIC	4.507	Up-regulation
CAMK_PKD_PRKD1_ST	Q13936	CACNA1C	Q15139	PRKD1	S1645	R1643Q	1643	Missense	proximal	-2	no	8.255	6.287	EPSD	COSMIC	4.507	Down-regulation
CAMK_PKD_PRKD1_ST	Q13936	CACNA1C	Q15139	PRKD1	S1645	S1645C	1645	Missense	central	0	yes	8.255	0.000	EPSD	COSMIC	4.507	Loss
CAMK_PKD_PRKD1_ST	Q13936	CACNA1C	Q15139	PRKD1	S1645	K1638E	1638	Missense	distal	-7	no	8.255	8.181	EPSD	COSMIC	4.507	Down-regulation
CAMK_PKD_PRKD1_ST	Q13936	CACNA1C	Q15139	PRKD1	S1692	R1694P	1694	Missense	proximal	2	no	5.756	5.702	EPSD	COSMIC	4.507	Down-regulation
CAMK_PKD_PRKD1_ST	Q13936	CACNA1C	Q15139	PRKD1	S1692	A1696V	1696	Missense	distal	4	no	5.756	5.772	EPSD	COSMIC	4.507	Up-regulation
CAMK_PKD_PRKD1_ST	Q13936	CACNA1C	Q15139	PRKD1	S1692	G1689N	1689	Missense	distal	-3	no	5.756	4.940	EPSD	COSMIC	4.507	Down-regulation
CAMK_PKD_PRKD1_ST	Q13936	CACNA1C	Q15139	PRKD1	S1692	V1688L	1688	Missense	distal	-4	no	5.756	5.758	EPSD	COSMIC	4.507	Up-regulation
CAMK_PKD_PRKD1_ST	Q13936	CACNA1C	Q15139	PRKD1	S1718	R1715G	1715	Missense	distal	-3	no	7.118	2.352	EPSD	COSMIC	4.507	Loss
CAMK_PKD_PRKD1_ST	Q13936	CACNA1C	Q15139	PRKD1	S1718	A1716S	1716	Missense	proximal	-2	no	7.118	6.827	EPSD	COSMIC	4.507	Down-regulation
CAMK_PKD_PRKD1_ST	Q13936	CACNA1C	Q15139	PRKD1	S1718	R1714S	1714	Missense	distal	-4	no	7.118	7.115	EPSD	COSMIC	4.507	Down-regulation
CAMK_PKD_PRKD1_ST	Q13936	CACNA1C	Q15139	PRKD1	S1718	S1718R	1718	Missense	central	0	yes	7.118	0.000	EPSD	COSMIC	4.507	Loss
CAMK_PKD_PRKD1_ST	Q13936	CACNA1C	Q15139	PRKD1	S1718	R1714P	1714	Missense	distal	-4	no	7.118	7.112	EPSD	COSMIC;GDSC;CCLE	4.507	Down-regulation
CAMK_PKD_PRKD1_ST	Q13936	CACNA1C	Q15139	PRKD1	S1718	R1714G	1714	Missense	distal	-4	no	7.118	7.106	EPSD	COSMIC	4.507	Down-regulation
CAMK_PKD_PRKD1_ST	Q13936	CACNA1C	Q15139	PRKD1	S1718	A1716T	1716	Missense	proximal	-2	no	7.118	6.511	EPSD	COSMIC	4.507	Down-regulation
CAMK_PKD_PRKD1_ST	Q13936	CACNA1C	Q15139	PRKD1	S1718	R1715W	1715	Missense	distal	-3	no	7.118	1.745	EPSD	COSMIC	4.507	Loss
CAMK_PKD_PRKD1_ST	Q13936	CACNA1C	Q15139	PRKD1	S1718	A1716D	1716	Missense	proximal	-2	no	7.118	4.887	EPSD	COSMIC	4.507	Down-regulation
CAMK_PKD_PRKD1_ST	Q13936	CACNA1C	Q15139	PRKD1	S1718	T1722I	1722	Missense	distal	4	no	7.118	7.115	EPSD	COSMIC	4.507	Down-regulation
CAMK_PKD_PRKD1_ST	Q13936	CACNA1C	Q15139	PRKD1	S1736	S1736G	1736	Missense	central	0	yes	5.230	0.000	EPSD	COSMIC	4.507	Loss
CAMK_PKD_PRKD1_ST	Q13936	CACNA1C	Q15139	PRKD1	S1736	A1734T	1734	Missense	proximal	-2	no	5.230	4.623	EPSD	COSMIC	4.507	Down-regulation
CAMK_PKD_PRKD1_ST	Q13936	CACNA1C	Q15139	PRKD1	S1736	S1739F	1739	Missense	distal	3	no	5.230	5.205	EPSD	COSMIC	4.507	Down-regulation
CAMK_PKD_PRKD1_ST	Q13936	CACNA1C	Q15139	PRKD1	S1736	A1730T	1730	Missense	distal	-6	no	5.230	5.209	EPSD	COSMIC	4.507	Down-regulation
CAMK_PKD_PRKD1_ST	Q13936	CACNA1C	Q15139	PRKD1	S1901	R1902W	1902	Missense	proximal	1	no	5.708	5.707	EPSD	COSMIC	4.507	Down-regulation
CAMK_PKD_PRKD1_ST	Q13936	CACNA1C	Q15139	PRKD1	S1901	S1904F	1904	Missense	distal	3	no	5.708	5.683	EPSD	COSMIC	4.507	Down-regulation
CAMK_PKD_PRKD1_ST	Q13936	CACNA1C	Q15139	PRKD1	S1901	H1900Q	1900	Missense	proximal	-1	no	5.708	5.697	EPSD	COSMIC	4.507	Down-regulation
CAMK_PKD_PRKD1_ST	Q13936	CACNA1C	Q15139	PRKD1	S1901	H1900P	1900	Missense	proximal	-1	no	5.708	5.644	EPSD	COSMIC	4.507	Down-regulation
CAMK_PKD_PRKD1_ST	Q13936	CACNA1C	Q15139	PRKD1	S1904	R1902W	1902	Missense	proximal	-2	no	5.394	1.931	EPSD	COSMIC	4.507	Loss
CAMK_PKD_PRKD1_ST	Q13936	CACNA1C	Q15139	PRKD1	S1904	S1904F	1904	Missense	central	0	yes	5.394	0.000	EPSD	COSMIC	4.507	Loss
CAMK_PKD_PRKD1_ST	Q13936	CACNA1C	Q15139	PRKD1	S1904	H1900Q	1900	Missense	distal	-4	no	5.394	5.395	EPSD	COSMIC	4.507	Up-regulation
CAMK_PKD_PRKD1_ST	Q13936	CACNA1C	Q15139	PRKD1	S1904	H1900P	1900	Missense	distal	-4	no	5.394	5.393	EPSD	COSMIC	4.507	Down-regulation
CAMK_PKD_PRKD1_ST	Q13936	CACNA1C	Q15139	PRKD1	T1953	Q1951R	1951	Missense	proximal	-2	no	4.413	6.380	EPSD	COSMIC	4.507	Gain
CAMK_PKD_PRKD1_ST	Q13936	CACNA1C	Q15139	PRKD1	S1981	S1975L	1975	Missense	distal	-6	no	10.753	10.720	PhosphoSitePlus	COSMIC	4.507	Down-regulation
CAMK_PKD_PRKD1_ST	Q13936	CACNA1C	Q15139	PRKD1	S1981	A1974V	1974	Missense	distal	-7	no	10.753	10.241	PhosphoSitePlus	COSMIC	4.507	Down-regulation
CAMK_PKD_PRKD1_ST	Q13936	CACNA1C	Q15139	PRKD1	S1981	R1979W	1979	Missense	proximal	-2	no	10.753	7.290	PhosphoSitePlus	COSMIC	4.507	Down-regulation
CAMK_PKD_PRKD1_ST	Q13936	CACNA1C	Q15139	PRKD1	S1981	R1979Q	1979	Missense	proximal	-2	no	10.753	8.785	PhosphoSitePlus	COSMIC	4.507	Down-regulation
CAMK_PKD_PRKD1_ST	Q13936	CACNA1C	Q15139	PRKD1	S1981	A1974T	1974	Missense	distal	-7	no	10.753	10.493	PhosphoSitePlus	COSMIC	4.507	Down-regulation
CAMK_PKD_PRKD1_ST	Q13936	CACNA1C	Q15139	PRKD1	S2069	L2066R	2066	Missense	distal	-3	no	0.190	5.117	EPSD	COSMIC	4.507	Gain
CAMK_PKD_PRKD1_ST	Q13936	CACNA1C	Q15139	PRKD1	S2098	A2091T	2091	Missense	distal	-7	no	7.844	7.584	EPSD	COSMIC	4.507	Down-regulation
CAMK_PKD_PRKD1_ST	Q14247	CTTN	Q15139	PRKD1	S150	G143W	143	Missense	distal	-7	no	5.979	5.958	EPSD	COSMIC	4.507	Down-regulation
CAMK_PKD_PRKD1_ST	Q14247	CTTN	Q15139	PRKD1	S150	Y154C	154	Missense	distal	4	no	5.979	5.960	EPSD	COSMIC;CCLE	4.507	Down-regulation
CAMK_PKD_PRKD1_ST	Q14247	CTTN	Q15139	PRKD1	S187	D190N	190	Missense	distal	3	no	5.401	5.413	EPSD	COSMIC	4.507	Up-regulation
CAMK_PKD_PRKD1_ST	Q14247	CTTN	Q15139	PRKD1	S192	D190N	190	Missense	proximal	-2	no	4.857	5.270	EPSD	COSMIC	4.507	Up-regulation
CAMK_PKD_PRKD1_ST	Q14247	CTTN	Q15139	PRKD1	S224	S224F	224	Missense	central	0	yes	5.481	0.000	EPSD	COSMIC	4.507	Loss
CAMK_PKD_PRKD1_ST	Q14247	CTTN	Q15139	PRKD1	S261	S261F	261	Missense	central	0	yes	5.673	0.000	EPSD	COSMIC	4.507	Loss
CAMK_PKD_PRKD1_ST	Q14247	CTTN	Q15139	PRKD1	S282	R279W	279	Missense	distal	-3	no	7.855	2.482	EPSD	COSMIC	4.507	Loss
CAMK_PKD_PRKD1_ST	Q14247	CTTN	Q15139	PRKD1	S282	F287L	287	Missense	distal	5	no	7.855	7.909	EPSD	COSMIC	4.507	Up-regulation
CAMK_PKD_PRKD1_ST	Q14247	CTTN	Q15139	PRKD1	S282	S277L	277	Missense	distal	-5	no	7.855	10.119	EPSD	COSMIC	4.507	Up-regulation
CAMK_PKD_PRKD1_ST	Q14247	CTTN	Q15139	PRKD1	T399	Q394K	394	Missense	distal	-5	no	4.593	4.284	EPSD	COSMIC	4.507	Loss
CAMK_PKD_PRKD1_ST	Q14247	CTTN	Q15139	PRKD1	T399	R396T	396	Missense	distal	-3	no	4.593	1.082	EPSD	COSMIC	4.507	Loss
CAMK_PKD_PRKD1_ST	Q14247	CTTN	Q15139	PRKD1	S417	T411I	411	Missense	distal	-6	no	4.786	4.781	EPSD	COSMIC	4.507	Down-regulation
CAMK_PKD_PRKD1_ST	Q14247	CTTN	Q15139	PRKD1	S417	V420I	420	Missense	distal	3	no	4.786	4.785	EPSD	COSMIC	4.507	Down-regulation
CAMK_PKD_PRKD1_ST	P05412	JUN	Q15139	PRKD1	S58	L53F	53	Missense	distal	-5	no	6.725	3.573	EPSD	COSMIC	4.507	Loss
CAMK_PKD_PRKD1_ST	P05412	JUN	Q15139	PRKD1	S58	K56N	56	Missense	proximal	-2	no	6.725	4.884	EPSD	COSMIC	4.507	Down-regulation
CAMK_PKD_PRKD1_ST	P05412	JUN	Q15139	PRKD1	S58	P51T	51	Missense	distal	-7	no	6.725	6.669	EPSD	COSMIC;CCLE	4.507	Down-regulation
CAMK_PKD_PRKD1_ST	P05412	JUN	Q15139	PRKD1	S58	L61F	61	Missense	distal	3	no	6.725	6.708	EPSD	COSMIC	4.507	Down-regulation
CAMK_PKD_PRKD1_ST	P05412	JUN	Q15139	PRKD1	S73	R78H	78	Missense	distal	5	no	6.605	6.569	EPSD	COSMIC	4.507	Down-regulation
CAMK_PKD_PRKD1_ST	P05412	JUN	Q15139	PRKD1	S84	I81M	81	Missense	distal	-3	no	4.633	5.595	EPSD	COSMIC	4.507	Up-regulation
CAMK_PKD_PRKD1_ST	P05412	JUN	Q15139	PRKD1	S84	R78H	78	Missense	distal	-6	no	4.633	4.620	EPSD	COSMIC	4.507	Down-regulation
CAMK_PKD_PRKD1_ST	Q9UBF8	PI4KB	Q15139	PRKD1	S128	L131P	131	Missense	distal	3	no	5.279	5.277	EPSD	COSMIC	4.507	Down-regulation
CAMK_PKD_PRKD1_ST	Q9UBF8	PI4KB	Q15139	PRKD1	S128	Q121H	121	Missense	distal	-7	no	5.279	5.191	EPSD	COSMIC	4.507	Down-regulation
CAMK_PKD_PRKD1_ST	Q9UBF8	PI4KB	Q15139	PRKD1	S128	L133P	133	Missense	distal	5	no	5.279	5.290	EPSD	COSMIC	4.507	Up-regulation
CAMK_PKD_PRKD1_ST	Q9UBF8	PI4KB	Q15139	PRKD1	S128	R132Q	132	Missense	distal	4	no	5.279	5.282	EPSD	COSMIC	4.507	Up-regulation
CAMK_PKD_PRKD1_ST	Q9UBF8	PI4KB	Q15139	PRKD1	S128	S128L	128	Missense	central	0	yes	5.279	0.000	EPSD	COSMIC	4.507	Loss
CAMK_PKD_PRKD1_ST	Q9UBF8	PI4KB	Q15139	PRKD1	S205	L210I	210	Missense	distal	5	no	5.620	5.615	EPSD	COSMIC	4.507	Down-regulation
CAMK_PKD_PRKD1_ST	Q9UBF8	PI4KB	Q15139	PRKD1	S205	Q211K	211	Missense	distal	6	no	5.620	5.636	EPSD	COSMIC	4.507	Up-regulation
CAMK_PKD_PRKD1_ST	Q9UBF8	PI4KB	Q15139	PRKD1	S205	H200Q	200	Missense	distal	-5	no	5.620	5.029	EPSD	COSMIC	4.507	Down-regulation
CAMK_PKD_PRKD1_ST	Q9UBF8	PI4KB	Q15139	PRKD1	S205	R203H	203	Missense	proximal	-2	no	5.620	3.674	EPSD	COSMIC	4.507	Loss
CAMK_PKD_PRKD1_ST	Q9UBF8	PI4KB	Q15139	PRKD1	S205	Q204H	204	Missense	proximal	-1	no	5.620	5.631	EPSD	COSMIC	4.507	Up-regulation
CAMK_PKD_PRKD1_ST	Q9UBF8	PI4KB	Q15139	PRKD1	S205	S209F	209	Missense	distal	4	no	5.620	5.644	EPSD	COSMIC	4.507	Up-regulation
CAMK_PKD_PRKD1_ST	Q9UBF8	PI4KB	Q15139	PRKD1	S205	R203L	203	Missense	proximal	-2	no	5.620	2.512	EPSD	COSMIC	4.507	Loss
CAMK_PKD_PRKD1_ST	Q9UBF8	PI4KB	Q15139	PRKD1	S275	R270M	270	Missense	distal	-5	no	4.526	4.779	EPSD	COSMIC	4.507	Up-regulation
CAMK_PKD_PRKD1_ST	Q9UBF8	PI4KB	Q15139	PRKD1	S275	R274C	274	Missense	proximal	-1	no	4.526	4.333	EPSD	COSMIC	4.507	Loss
CAMK_PKD_PRKD1_ST	Q9UBF8	PI4KB	Q15139	PRKD1	S275	R274H	274	Missense	proximal	-1	no	4.526	4.413	EPSD	COSMIC	4.507	Loss
CAMK_PKD_PRKD1_ST	Q9UBF8	PI4KB	Q15139	PRKD1	S277	R270M	270	Missense	distal	-7	no	9.036	8.606	EPSD	COSMIC	4.507	Down-regulation
CAMK_PKD_PRKD1_ST	Q9UBF8	PI4KB	Q15139	PRKD1	S277	R274C	274	Missense	distal	-3	no	9.036	4.939	EPSD	COSMIC	4.507	Down-regulation
CAMK_PKD_PRKD1_ST	Q9UBF8	PI4KB	Q15139	PRKD1	S277	R274H	274	Missense	distal	-3	no	9.036	5.049	EPSD	COSMIC	4.507	Down-regulation
CAMK_PKD_PRKD1_ST	Q9UBF8	PI4KB	Q15139	PRKD1	S294	S294I	294	Missense	central	0	yes	8.876	0.000	PhosphoSitePlus	COSMIC	4.507	Loss
CAMK_PKD_PRKD1_ST	Q9UBF8	PI4KB	Q15139	PRKD1	T341	G336D	336	Missense	distal	-5	no	4.437	4.630	EPSD	COSMIC	4.507	Gain
CAMK_PKD_PRKD1_ST	Q9UBF8	PI4KB	Q15139	PRKD1	S425	R422Q	422	Missense	distal	-3	no	5.053	0.640	EPSD	COSMIC	4.507	Loss
CAMK_PKD_PRKD1_ST	Q9UBF8	PI4KB	Q15139	PRKD1	S425	P419S	419	Missense	distal	-6	no	5.053	5.062	EPSD	COSMIC	4.507	Up-regulation
CAMK_PKD_PRKD1_ST	Q9UBF8	PI4KB	Q15139	PRKD1	S425	R424Q	424	Missense	proximal	-1	no	5.053	4.929	EPSD	COSMIC	4.507	Down-regulation
CAMK_PKD_PRKD1_ST	Q9UBF8	PI4KB	Q15139	PRKD1	S425	P419H	419	Missense	distal	-6	no	5.053	5.054	EPSD	COSMIC	4.507	Up-regulation
CAMK_PKD_PRKD1_ST	Q9UBF8	PI4KB	Q15139	PRKD1	S425	P419F	419	Missense	distal	-6	no	5.053	5.034	EPSD	COSMIC	4.507	Down-regulation
CAMK_PKD_PRKD1_ST	Q9UBF8	PI4KB	Q15139	PRKD1	S425	E420K	420	Missense	distal	-5	no	5.053	5.197	EPSD	COSMIC	4.507	Up-regulation
CAMK_PKD_PRKD1_ST	Q9UBF8	PI4KB	Q15139	PRKD1	S425	R424L	424	Missense	proximal	-1	no	5.053	4.939	EPSD	COSMIC	4.507	Down-regulation
CAMK_PKD_PRKD1_ST	Q9UBF8	PI4KB	Q15139	PRKD1	S425	E420V	420	Missense	distal	-5	no	5.053	6.567	EPSD	COSMIC	4.507	Up-regulation
CAMK_PKD_PRKD1_ST	Q9UBF8	PI4KB	Q15139	PRKD1	S425	R427Q	427	Missense	proximal	2	no	5.053	5.036	EPSD	COSMIC	4.507	Down-regulation
CAMK_PKD_PRKD1_ST	Q9UBF8	PI4KB	Q15139	PRKD1	S445	T448A	448	Missense	distal	3	no	7.009	7.028	EPSD	COSMIC	4.507	Up-regulation
CAMK_PKD_PRKD1_ST	Q9UBF8	PI4KB	Q15139	PRKD1	S445	R442Q	442	Missense	distal	-3	no	7.009	2.596	EPSD	COSMIC	4.507	Loss
CAMK_PKD_PRKD1_ST	Q9UBF8	PI4KB	Q15139	PRKD1	S445	G444D	444	Missense	proximal	-1	no	7.009	7.016	EPSD	COSMIC	4.507	Up-regulation
CAMK_PKD_PRKD1_ST	Q9UBF8	PI4KB	Q15139	PRKD1	S445	S445L	445	Missense	central	0	yes	7.009	0.000	EPSD	COSMIC	4.507	Loss
CAMK_PKD_PRKD1_ST	Q9UBF8	PI4KB	Q15139	PRKD1	S445	A443D	443	Missense	proximal	-2	no	7.009	4.777	EPSD	COSMIC	4.507	Down-regulation
CAMK_PKD_PRKD1_ST	Q9UBF8	PI4KB	Q15139	PRKD1	S511	R509H	509	Missense	proximal	-2	no	9.801	7.855	EPSD	COSMIC	4.507	Down-regulation
CAMK_PKD_PRKD1_ST	Q9UBF8	PI4KB	Q15139	PRKD1	S511	D505G	505	Missense	distal	-6	no	9.801	9.794	EPSD	COSMIC	4.507	Down-regulation
CAMK_PKD_PRKD1_ST	Q9UBF8	PI4KB	Q15139	PRKD1	S511	R507H	507	Missense	distal	-4	no	9.801	9.796	EPSD	COSMIC	4.507	Down-regulation
CAMK_PKD_PRKD1_ST	Q9UBF8	PI4KB	Q15139	PRKD1	S511	L514Q	514	Missense	distal	3	no	9.801	9.809	EPSD	COSMIC	4.507	Up-regulation
CAMK_PKD_PRKD1_ST	Q9UBF8	PI4KB	Q15139	PRKD1	S511	R509C	509	Missense	proximal	-2	no	9.801	7.193	EPSD	COSMIC	4.507	Down-regulation
CAMK_PKD_PRKD1_ST	Q9UBF8	PI4KB	Q15139	PRKD1	S511	R508L	508	Missense	distal	-3	no	9.801	4.874	EPSD	COSMIC	4.507	Down-regulation
CAMK_PKD_PRKD1_ST	P48426	PIP4K2A	Q15139	PRKD1	S222	R219T	219	Missense	distal	-3	no	7.734	4.223	EPSD	COSMIC;GDSC	4.507	Loss
CAMK_PKD_PRKD1_ST	P48426	PIP4K2A	Q15139	PRKD1	S222	K224N	224	Missense	proximal	2	no	7.734	7.678	EPSD	COSMIC	4.507	Down-regulation
CAMK_PKD_PRKD1_ST	Q9Y3E5	PTRH2	Q15139	PRKD1	S87	S92L	92	Missense	distal	5	no	5.243	5.186	EPSD;PhosphoSitePlus	COSMIC	4.507	Down-regulation
CAMK_PKD_PRKD1_ST	Q9Y3E5	PTRH2	Q15139	PRKD1	S87	H88Y	88	Missense	proximal	1	no	5.243	5.242	EPSD;PhosphoSitePlus	COSMIC	4.507	Down-regulation
CAMK_PKD_PRKD1_ST	Q9BST9	RTKN	Q15139	PRKD1	S106	S102P	102	Missense	distal	-4	no	8.272	8.269	EPSD	COSMIC	4.507	Down-regulation
CAMK_PKD_PRKD1_ST	Q9BST9	RTKN	Q15139	PRKD1	S106	P110L	110	Missense	distal	4	no	8.272	8.269	EPSD	COSMIC	4.507	Down-regulation
CAMK_PKD_PRKD1_ST	Q9BST9	RTKN	Q15139	PRKD1	S106	R103Q	103	Missense	distal	-3	no	8.272	3.860	EPSD	COSMIC	4.507	Loss
CAMK_PKD_PRKD1_ST	Q9BST9	RTKN	Q15139	PRKD1	S115	P110L	110	Missense	distal	-5	no	3.151	5.997	EPSD	COSMIC	4.507	Gain
CAMK_PKD_PRKD1_ST	Q9BST9	RTKN	Q15139	PRKD1	S218	S219L	219	Missense	proximal	1	no	6.138	6.137	EPSD	COSMIC	4.507	Down-regulation
CAMK_PKD_PRKD1_ST	Q9BST9	RTKN	Q15139	PRKD1	S225	S219L	219	Missense	distal	-6	no	4.593	4.560	EPSD	COSMIC	4.507	Down-regulation
CAMK_PKD_PRKD1_ST	Q9BST9	RTKN	Q15139	PRKD1	T518	P516S	516	Missense	proximal	-2	no	4.736	5.057	EPSD	COSMIC	4.507	Up-regulation
CAMK_PKD_PRKD1_ST	Q9BST9	RTKN	Q15139	PRKD1	T518	R517Q	517	Missense	proximal	-1	no	4.736	4.612	EPSD	COSMIC	4.507	Down-regulation
CAMK_PKD_PRKD1_ST	Q9BST9	RTKN	Q15139	PRKD1	S520	P516S	516	Missense	distal	-4	no	7.065	7.068	EPSD	COSMIC	4.507	Up-regulation
CAMK_PKD_PRKD1_ST	Q9BST9	RTKN	Q15139	PRKD1	S520	R517Q	517	Missense	distal	-3	no	7.065	2.653	EPSD	COSMIC	4.507	Loss
CAMK_PKD_PRKD1_ST	Q9BST9	RTKN	Q15139	PRKD1	S534	R533H	533	Missense	proximal	-1	no	6.946	6.833	EPSD	COSMIC	4.507	Down-regulation
CAMK_PKD_PRKD1_ST	Q9BST9	RTKN	Q15139	PRKD1	S534	S529P	529	Missense	distal	-5	no	6.946	6.364	EPSD	COSMIC	4.507	Down-regulation
CAMK_PKD_PRKD1_ST	Q9BST9	RTKN	Q15139	PRKD1	S543	G548V	548	Missense	distal	5	no	4.459	4.523	EPSD	COSMIC	4.507	Gain
CAMK_PKD_PRKD1_ST	Q12809	KCNH2	Q15139	PRKD1	S239	R242H	242	Missense	distal	3	no	4.803	4.795	EPSD	COSMIC	4.507	Down-regulation
CAMK_PKD_PRKD1_ST	Q12809	KCNH2	Q15139	PRKD1	S239	R242C	242	Missense	distal	3	no	4.803	4.788	EPSD	COSMIC	4.507	Down-regulation
CAMK_PKD_PRKD1_ST	Q12809	KCNH2	Q15139	PRKD1	S239	A244V	244	Missense	distal	5	no	4.803	4.721	EPSD	COSMIC	4.507	Down-regulation
CAMK_PKD_PRKD1_ST	Q12809	KCNH2	Q15139	PRKD1	S283	R281S	281	Missense	proximal	-2	no	8.866	7.021	EPSD	COSMIC	4.507	Down-regulation
CAMK_PKD_PRKD1_ST	Q12809	KCNH2	Q15139	PRKD1	S283	R281C	281	Missense	proximal	-2	no	8.866	6.257	EPSD	COSMIC	4.507	Down-regulation
CAMK_PKD_PRKD1_ST	Q12809	KCNH2	Q15139	PRKD1	S284	R281S	281	Missense	distal	-3	no	7.574	3.138	PhosphoSitePlus	COSMIC	4.507	Loss
CAMK_PKD_PRKD1_ST	Q12809	KCNH2	Q15139	PRKD1	S284	R281C	281	Missense	distal	-3	no	7.574	3.477	PhosphoSitePlus	COSMIC	4.507	Loss
CAMK_PKD_PRKD1_ST	Q12809	KCNH2	Q15139	PRKD1	S304	P310Q	310	Missense	distal	6	no	6.686	6.670	EPSD	COSMIC	4.507	Down-regulation
CAMK_PKD_PRKD1_ST	Q12809	KCNH2	Q15139	PRKD1	S304	A307T	307	Missense	distal	3	no	6.686	6.667	EPSD	COSMIC;CCLE	4.507	Down-regulation
CAMK_PKD_PRKD1_ST	Q12809	KCNH2	Q15139	PRKD1	S304	P298S	298	Missense	distal	-6	no	6.686	6.696	EPSD	COSMIC	4.507	Up-regulation
CAMK_PKD_PRKD1_ST	Q12809	KCNH2	Q15139	PRKD1	S304	P310S	310	Missense	distal	6	no	6.686	6.666	EPSD	COSMIC	4.507	Down-regulation
CAMK_PKD_PRKD1_ST	Q12809	KCNH2	Q15139	PRKD1	S320	R326H	326	Missense	distal	6	no	5.175	5.173	EPSD	COSMIC	4.507	Down-regulation
CAMK_PKD_PRKD1_ST	Q12809	KCNH2	Q15139	PRKD1	S320	G314C	314	Missense	distal	-6	no	5.175	5.194	EPSD	COSMIC	4.507	Up-regulation
CAMK_PKD_PRKD1_ST	Q12809	KCNH2	Q15139	PRKD1	S320	G314S	314	Missense	distal	-6	no	5.175	5.209	EPSD	COSMIC	4.507	Up-regulation
CAMK_PKD_PRKD1_ST	Q12809	KCNH2	Q15139	PRKD1	S320	L315F	315	Missense	distal	-5	no	5.175	2.023	EPSD	COSMIC	4.507	Loss
CAMK_PKD_PRKD1_ST	Q12809	KCNH2	Q15139	PRKD1	S354	I359K	359	Missense	distal	5	no	4.638	4.666	EPSD	COSMIC;CCLE	4.507	Up-regulation
CAMK_PKD_PRKD1_ST	Q12809	KCNH2	Q15139	PRKD1	S354	R356S	356	Missense	proximal	2	no	4.638	4.627	EPSD	COSMIC	4.507	Down-regulation
CAMK_PKD_PRKD1_ST	Q12809	KCNH2	Q15139	PRKD1	S354	P352S	352	Missense	proximal	-2	no	4.638	4.960	EPSD	COSMIC	4.507	Up-regulation
CAMK_PKD_PRKD1_ST	Q12809	KCNH2	Q15139	PRKD1	S354	R356H	356	Missense	proximal	2	no	4.638	4.600	EPSD	COSMIC	4.507	Down-regulation
CAMK_PKD_PRKD1_ST	Q12809	KCNH2	Q15139	PRKD1	T675	Y673H	673	Missense	proximal	-2	no	2.974	4.839	EPSD	COSMIC;CCLE	4.507	Gain
CAMK_PKD_PRKD1_ST	Q12809	KCNH2	Q15139	PRKD1	S890	R894H	894	Missense	distal	4	no	9.635	9.639	EPSD	COSMIC	4.507	Up-regulation
CAMK_PKD_PRKD1_ST	Q12809	KCNH2	Q15139	PRKD1	S890	R885C	885	Missense	distal	-5	no	9.635	9.206	EPSD	COSMIC	4.507	Down-regulation
CAMK_PKD_PRKD1_ST	Q12809	KCNH2	Q15139	PRKD1	S890	R885H	885	Missense	distal	-5	no	9.635	9.513	EPSD	COSMIC;GDSC;CCLE	4.507	Down-regulation
CAMK_PKD_PRKD1_ST	Q12809	KCNH2	Q15139	PRKD1	S890	R883P	883	Missense	distal	-7	no	9.635	9.242	EPSD	COSMIC	4.507	Down-regulation
CAMK_PKD_PRKD1_ST	Q12809	KCNH2	Q15139	PRKD1	S890	R883Q	883	Missense	distal	-7	no	9.635	9.361	EPSD	COSMIC	4.507	Down-regulation
CAMK_PKD_PRKD1_ST	Q12809	KCNH2	Q15139	PRKD1	S890	T895M	895	Missense	distal	5	no	9.635	9.668	EPSD	COSMIC;GDSC;CCLE	4.507	Up-regulation
CAMK_PKD_PRKD1_ST	Q12809	KCNH2	Q15139	PRKD1	T895	K897T	897	Missense	proximal	2	no	6.730	6.690	EPSD	COSMIC	4.507	Down-regulation
CAMK_PKD_PRKD1_ST	Q12809	KCNH2	Q15139	PRKD1	T895	R894H	894	Missense	proximal	-1	no	6.730	6.617	EPSD	COSMIC	4.507	Down-regulation
CAMK_PKD_PRKD1_ST	Q12809	KCNH2	Q15139	PRKD1	T895	T895M	895	Missense	central	0	yes	6.730	0.000	EPSD	COSMIC;GDSC;CCLE	4.507	Loss
CAMK_PKD_PRKD1_ST	Q12809	KCNH2	Q15139	PRKD1	S1137	L1136I	1136	Missense	proximal	-1	no	9.193	9.087	EPSD	COSMIC	4.507	Down-regulation
CAMK_PKD_PRKD1_ST	Q12809	KCNH2	Q15139	PRKD1	S1137	P1139S	1139	Missense	proximal	2	no	9.193	9.235	EPSD	COSMIC	4.507	Up-regulation
CAMK_PKD_PRKD1_ST	Q12809	KCNH2	Q15139	PRKD1	S1137	G1140V	1140	Missense	distal	3	no	9.193	9.206	EPSD	COSMIC;CCLE	4.507	Up-regulation
CAMK_PKD_PRKD1_ST	Q12809	KCNH2	Q15139	PRKD1	S1137	E1130D	1130	Missense	distal	-7	no	9.193	8.806	EPSD	COSMIC	4.507	Down-regulation
CAMK_PKD_PRKD1_ST	Q12809	KCNH2	Q15139	PRKD1	S1137	A1144D	1144	Missense	distal	7	no	9.193	9.192	EPSD	COSMIC	4.507	Down-regulation
CAMK_PKD_PRKD1_ST	Q12809	KCNH2	Q15139	PRKD1	S1155	H1151Q	1151	Missense	distal	-4	no	9.463	9.464	EPSD	COSMIC	4.507	Up-regulation
CAMK_PKD_PRKD1_ST	P53367	ARFIP1	Q15139	PRKD1	S28	R25H	25	Missense	distal	-3	no	6.217	2.230	EPSD	COSMIC	4.507	Loss
CAMK_PKD_PRKD1_ST	P53367	ARFIP1	Q15139	PRKD1	S28	S28N	28	Missense	central	0	yes	6.217	0.000	EPSD	COSMIC	4.507	Loss
CAMK_PKD_PRKD1_ST	P53367	ARFIP1	Q15139	PRKD1	S93	S86R	86	Missense	distal	-7	no	4.369	4.649	EPSD	COSMIC	4.507	Gain
CAMK_PKD_PRKD1_ST	P53367	ARFIP1	Q15139	PRKD1	S132	K137N	137	Missense	distal	5	no	8.411	8.386	PhosphoSitePlus;EPSD	COSMIC	4.507	Down-regulation
CAMK_PKD_PRKD1_ST	P05549	TFAP2A	Q15139	PRKD1	S119	P123L	123	Missense	distal	4	no	7.317	7.314	EPSD	COSMIC	4.507	Down-regulation
CAMK_PKD_PRKD1_ST	P05549	TFAP2A	Q15139	PRKD1	S119	R125Q	125	Missense	distal	6	no	7.317	7.309	EPSD	COSMIC	4.507	Down-regulation
CAMK_PKD_PRKD1_ST	P05549	TFAP2A	Q15139	PRKD1	S187	S187C	187	Missense	central	0	yes	6.466	0.000	EPSD	COSMIC	4.507	Loss
CAMK_PKD_PRKD1_ST	P05549	TFAP2A	Q15139	PRKD1	S187	S187F	187	Missense	central	0	yes	6.466	0.000	EPSD	COSMIC	4.507	Loss
CAMK_PKD_PRKD1_ST	P05549	TFAP2A	Q15139	PRKD1	S187	S183F	183	Missense	distal	-4	no	6.466	6.457	EPSD	COSMIC	4.507	Down-regulation
CAMK_PKD_PRKD1_ST	P05549	TFAP2A	Q15139	PRKD1	S219	G216C	216	Missense	distal	-3	no	4.733	5.403	EPSD	COSMIC;GDSC;CCLE	4.507	Up-regulation
CAMK_PKD_PRKD1_ST	P05549	TFAP2A	Q15139	PRKD1	S219	S213L	213	Missense	distal	-6	no	4.733	4.700	EPSD	COSMIC	4.507	Down-regulation
CAMK_PKD_PRKD1_ST	P05549	TFAP2A	Q15139	PRKD1	S219	L221I	221	Missense	proximal	2	no	4.733	4.725	EPSD	COSMIC	4.507	Down-regulation
CAMK_PKD_PRKD1_ST	P05549	TFAP2A	Q15139	PRKD1	S225	L221I	221	Missense	distal	-4	no	5.134	5.133	EPSD	COSMIC	4.507	Down-regulation
CAMK_PKD_PRKD1_ST	P05549	TFAP2A	Q15139	PRKD1	S239	P240A	240	Missense	proximal	1	no	9.468	9.469	EPSD	COSMIC	4.507	Up-regulation
CAMK_PKD_PRKD1_ST	P05549	TFAP2A	Q15139	PRKD1	S239	R236W	236	Missense	distal	-3	no	9.468	4.095	EPSD	COSMIC	4.507	Loss
CAMK_PKD_PRKD1_ST	P05549	TFAP2A	Q15139	PRKD1	S258	A256V	256	Missense	proximal	-2	no	9.564	7.408	PhosphoSitePlus;EPSD	COSMIC;GDSC;CCLE	4.507	Down-regulation
CAMK_PKD_PRKD1_ST	P05549	TFAP2A	Q15139	PRKD1	S258	G261R	261	Missense	distal	3	no	9.564	9.596	PhosphoSitePlus;EPSD	COSMIC	4.507	Up-regulation
CAMK_PKD_PRKD1_ST	P05549	TFAP2A	Q15139	PRKD1	S326	E319G	319	Missense	distal	-7	no	9.393	9.065	EPSD;PhosphoSitePlus	COSMIC	4.507	Down-regulation
CAMK_PKD_PRKD1_ST	P05549	TFAP2A	Q15139	PRKD1	S326	D327N	327	Missense	proximal	1	no	9.393	9.394	EPSD;PhosphoSitePlus	COSMIC	4.507	Up-regulation
CAMK_PKD_PRKD1_ST	P05549	TFAP2A	Q15139	PRKD1	S326	N322K	322	Missense	distal	-4	no	9.393	9.399	EPSD;PhosphoSitePlus	COSMIC	4.507	Up-regulation
CAMK_PKD_PRKD1_ST	Q13671	RIN1	Q15139	PRKD1	S210	Q212R	212	Missense	proximal	2	no	4.763	4.780	EPSD	COSMIC	4.507	Up-regulation
CAMK_PKD_PRKD1_ST	Q13671	RIN1	Q15139	PRKD1	S210	P204S	204	Missense	distal	-6	no	4.763	4.772	EPSD	COSMIC	4.507	Up-regulation
CAMK_PKD_PRKD1_ST	Q13671	RIN1	Q15139	PRKD1	S210	R209Q	209	Missense	proximal	-1	no	4.763	4.639	EPSD	COSMIC;CCLE	4.507	Down-regulation
CAMK_PKD_PRKD1_ST	Q13671	RIN1	Q15139	PRKD1	S291	G294W	294	Missense	distal	3	no	10.565	10.568	EPSD	COSMIC;CCLE	4.507	Up-regulation
CAMK_PKD_PRKD1_ST	Q13671	RIN1	Q15139	PRKD1	S292	G294W	294	Missense	proximal	2	no	9.735	9.755	EPSD;PhosphoSitePlus	COSMIC;CCLE	4.507	Up-regulation
CAMK_PKD_PRKD1_ST	Q13671	RIN1	Q15139	PRKD1	S351	L357Q	357	Missense	distal	6	no	9.466	9.443	PhosphoSitePlus;EPSD	COSMIC	4.507	Down-regulation
CAMK_PKD_PRKD1_ST	Q13671	RIN1	Q15139	PRKD1	S351	R348W	348	Missense	distal	-3	no	9.466	4.094	PhosphoSitePlus;EPSD	COSMIC	4.507	Loss
CAMK_PKD_PRKD1_ST	Q13671	RIN1	Q15139	PRKD1	S611	R608H	608	Missense	distal	-3	no	10.313	6.326	EPSD	COSMIC;GDSC	4.507	Down-regulation
CAMK_PKD_PRKD1_ST	Q13671	RIN1	Q15139	PRKD1	T695	L699F	699	Missense	distal	4	no	4.902	4.921	EPSD	COSMIC	4.507	Up-regulation
CAMK_PKD_PRKD1_ST	P16144	ITGB4	Q15139	PRKD1	S7	G3R	3	Missense	distal	-4	no	5.373	5.385	EPSD	COSMIC	4.507	Up-regulation
CAMK_PKD_PRKD1_ST	P16144	ITGB4	Q15139	PRKD1	S7	A10D	10	Missense	distal	3	no	5.373	5.341	EPSD	COSMIC	4.507	Down-regulation
CAMK_PKD_PRKD1_ST	P16144	ITGB4	Q15139	PRKD1	S368	A374S	374	Missense	distal	6	no	6.506	6.507	EPSD	COSMIC	4.507	Up-regulation
CAMK_PKD_PRKD1_ST	P16144	ITGB4	Q15139	PRKD1	S368	R367L	367	Missense	proximal	-1	no	6.506	6.393	EPSD	COSMIC	4.507	Down-regulation
CAMK_PKD_PRKD1_ST	P16144	ITGB4	Q15139	PRKD1	S397	T393M	393	Missense	distal	-4	no	4.644	4.646	EPSD	COSMIC;GDSC	4.507	Up-regulation
CAMK_PKD_PRKD1_ST	P16144	ITGB4	Q15139	PRKD1	S397	R401Q	401	Missense	distal	4	no	4.644	4.647	EPSD	COSMIC	4.507	Up-regulation
CAMK_PKD_PRKD1_ST	P16144	ITGB4	Q15139	PRKD1	S397	H399Y	399	Missense	proximal	2	no	4.644	4.501	EPSD	COSMIC	4.507	Loss
CAMK_PKD_PRKD1_ST	P16144	ITGB4	Q15139	PRKD1	S893	P891S	891	Missense	proximal	-2	no	7.001	7.323	EPSD	COSMIC	4.507	Up-regulation
CAMK_PKD_PRKD1_ST	P16144	ITGB4	Q15139	PRKD1	S893	P896L	896	Missense	distal	3	no	7.001	7.003	EPSD	COSMIC	4.507	Up-regulation
CAMK_PKD_PRKD1_ST	P16144	ITGB4	Q15139	PRKD1	S1140	K1142N	1142	Missense	proximal	2	no	5.892	5.836	EPSD	COSMIC;GDSC;CCLE	4.507	Down-regulation
CAMK_PKD_PRKD1_ST	P16144	ITGB4	Q15139	PRKD1	S1140	A1135V	1135	Missense	distal	-5	no	5.892	6.297	EPSD	COSMIC;GDSC;CCLE	4.507	Up-regulation
CAMK_PKD_PRKD1_ST	P16144	ITGB4	Q15139	PRKD1	S1358	V1353I	1353	Missense	distal	-5	no	7.979	7.856	EPSD	COSMIC	4.507	Down-regulation
CAMK_PKD_PRKD1_ST	P16144	ITGB4	Q15139	PRKD1	T1463	T1462N	1462	Missense	proximal	-1	no	7.080	7.034	EPSD	COSMIC	4.507	Down-regulation
CAMK_PKD_PRKD1_ST	P16144	ITGB4	Q15139	PRKD1	T1463	S1457Y	1457	Missense	distal	-6	no	7.080	7.048	EPSD	COSMIC	4.507	Down-regulation
CAMK_PKD_PRKD1_ST	P16144	ITGB4	Q15139	PRKD1	T1463	M1461V	1461	Missense	proximal	-2	no	7.080	5.575	EPSD	COSMIC	4.507	Down-regulation
CAMK_PKD_PRKD1_ST	P16144	ITGB4	Q15139	PRKD1	S1483	V1481M	1481	Missense	proximal	-2	no	5.460	6.964	EPSD	COSMIC	4.507	Up-regulation
CAMK_PKD_PRKD1_ST	P16144	ITGB4	Q15139	PRKD1	S1483	V1477M	1477	Missense	distal	-6	no	5.460	5.469	EPSD	COSMIC	4.507	Up-regulation
CAMK_PKD_PRKD1_ST	P16144	ITGB4	Q15139	PRKD1	S1483	L1488F	1488	Missense	distal	5	no	5.460	5.406	EPSD	COSMIC	4.507	Down-regulation
CAMK_PKD_PRKD1_ST	P16144	ITGB4	Q15139	PRKD1	T1487	V1481M	1481	Missense	distal	-6	no	5.200	5.209	EPSD	COSMIC	4.507	Up-regulation
CAMK_PKD_PRKD1_ST	P16144	ITGB4	Q15139	PRKD1	T1487	L1488F	1488	Missense	proximal	1	no	5.200	5.199	EPSD	COSMIC	4.507	Down-regulation
CAMK_PKD_PRKD1_ST	P16144	ITGB4	Q15139	PRKD1	S1511	Y1510C	1510	Missense	proximal	-1	no	6.409	6.598	EPSD	COSMIC	4.507	Up-regulation
CAMK_PKD_PRKD1_ST	P16144	ITGB4	Q15139	PRKD1	S1511	S1511F	1511	Missense	central	0	yes	6.409	0.000	EPSD	COSMIC	4.507	Loss
CAMK_PKD_PRKD1_ST	P16144	ITGB4	Q15139	PRKD1	S1604	R1601Q	1601	Missense	distal	-3	no	7.520	3.108	EPSD	COSMIC;CCLE	4.507	Loss
CAMK_PKD_PRKD1_ST	P16144	ITGB4	Q15139	PRKD1	S1653	S1656L	1656	Missense	distal	3	no	4.939	4.931	EPSD	COSMIC	4.507	Down-regulation
CAMK_PKD_PRKD1_ST	P16144	ITGB4	Q15139	PRKD1	S1653	L1657M	1657	Missense	distal	4	no	4.939	4.935	EPSD	COSMIC	4.507	Down-regulation
CAMK_PKD_PRKD1_ST	P16144	ITGB4	Q15139	PRKD1	S1653	L1647M	1647	Missense	distal	-6	no	4.939	4.961	EPSD	COSMIC	4.507	Up-regulation
CAMK_PKD_PRKD1_ST	P16144	ITGB4	Q15139	PRKD1	T1721	G1725R	1725	Missense	distal	4	no	5.259	5.229	EPSD	COSMIC	4.507	Down-regulation
CAMK_PKD_PRKD1_ST	P16144	ITGB4	Q15139	PRKD1	S1761	H1754Q	1754	Missense	distal	-7	no	4.466	4.553	EPSD	COSMIC	4.507	Gain
CAMK_PKD_PRKD1_ST	P16144	ITGB4	Q15139	PRKD1	S1791	R1794P	1794	Missense	distal	3	no	5.362	5.344	EPSD	COSMIC;CCLE	4.507	Down-regulation
CAMK_PKD_PRKD1_ST	P16144	ITGB4	Q15139	PRKD1	T1797	R1794P	1794	Missense	distal	-3	no	7.128	3.212	EPSD	COSMIC;CCLE	4.507	Loss
CAMK_PKD_PRKD1_ST	P16144	ITGB4	Q15139	PRKD1	T1797	S1802R	1802	Missense	distal	5	no	7.128	7.148	EPSD	COSMIC	4.507	Up-regulation
CAMK_PKD_PRKD1_ST	P16144	ITGB4	Q15139	PRKD1	T1806	S1802R	1802	Missense	distal	-4	no	6.907	6.911	EPSD	COSMIC	4.507	Up-regulation
CAMK_PKD_PRKD1_ST	P02686	MBP	Q15139	PRKD1	S26	K28N	28	Missense	proximal	2	no	5.290	5.234	EPSD	COSMIC	4.507	Down-regulation
CAMK_PKD_PRKD1_ST	P02686	MBP	Q15139	PRKD1	S40	S40C	40	Missense	central	0	yes	8.257	0.000	EPSD	COSMIC	4.507	Loss
CAMK_PKD_PRKD1_ST	P02686	MBP	Q15139	PRKD1	S96	R93C	93	Missense	distal	-3	no	7.949	3.852	EPSD	COSMIC	4.507	Loss
CAMK_PKD_PRKD1_ST	P02686	MBP	Q15139	PRKD1	S96	S96F	96	Missense	central	0	yes	7.949	0.000	EPSD	COSMIC	4.507	Loss
CAMK_PKD_PRKD1_ST	P02686	MBP	Q15139	PRKD1	S96	P100S	100	Missense	distal	4	no	7.949	7.941	EPSD	COSMIC	4.507	Down-regulation
CAMK_PKD_PRKD1_ST	P02686	MBP	Q15139	PRKD1	S128	A135V	135	Missense	distal	7	no	4.768	4.767	EPSD	COSMIC	4.507	Down-regulation
CAMK_PKD_PRKD1_ST	P02686	MBP	Q15139	PRKD1	S128	M134I	134	Missense	distal	6	no	4.768	4.786	EPSD	COSMIC	4.507	Up-regulation
CAMK_PKD_PRKD1_ST	P02686	MBP	Q15139	PRKD1	S128	A125T	125	Missense	distal	-3	no	4.768	4.502	EPSD	COSMIC	4.507	Loss
CAMK_PKD_PRKD1_ST	P02686	MBP	Q15139	PRKD1	S128	D132N	132	Missense	distal	4	no	4.768	4.757	EPSD	COSMIC	4.507	Down-regulation
CAMK_PKD_PRKD1_ST	P02686	MBP	Q15139	PRKD1	S128	V133L	133	Missense	distal	5	no	4.768	4.770	EPSD	COSMIC	4.507	Up-regulation
CAMK_PKD_PRKD1_ST	P02686	MBP	Q15139	PRKD1	S128	E129D	129	Missense	proximal	1	no	4.768	4.767	EPSD	COSMIC	4.507	Down-regulation
CAMK_PKD_PRKD1_ST	P02686	MBP	Q15139	PRKD1	S128	S128F	128	Missense	central	0	yes	4.768	0.000	EPSD	COSMIC	4.507	Loss
CAMK_PKD_PRKD1_ST	P02686	MBP	Q15139	PRKD1	S128	E122K	122	Missense	distal	-6	no	4.768	4.765	EPSD	COSMIC	4.507	Down-regulation
CAMK_PKD_PRKD1_ST	P02686	MBP	Q15139	PRKD1	S128	S130A	130	Missense	proximal	2	no	4.768	4.808	EPSD	COSMIC	4.507	Up-regulation
CAMK_PKD_PRKD1_ST	P02686	MBP	Q15139	PRKD1	S128	D123N	123	Missense	distal	-5	no	4.768	5.487	EPSD	COSMIC	4.507	Up-regulation
CAMK_PKD_PRKD1_ST	P02686	MBP	Q15139	PRKD1	S136	V133L	133	Missense	distal	-3	no	3.318	4.585	EPSD	COSMIC	4.507	Gain
CAMK_PKD_PRKD1_ST	P02686	MBP	Q15139	PRKD1	S141	A135V	135	Missense	distal	-6	no	6.683	6.658	EPSD	COSMIC	4.507	Down-regulation
CAMK_PKD_PRKD1_ST	P02686	MBP	Q15139	PRKD1	S141	M134I	134	Missense	distal	-7	no	6.683	6.477	EPSD	COSMIC	4.507	Down-regulation
CAMK_PKD_PRKD1_ST	P02686	MBP	Q15139	PRKD1	S141	K138R	138	Missense	distal	-3	no	6.683	9.355	EPSD	COSMIC;GDSC	4.507	Up-regulation
CAMK_PKD_PRKD1_ST	P02686	MBP	Q15139	PRKD1	S141	S141A	141	Missense	central	0	yes	6.683	0.000	EPSD	COSMIC	4.507	Loss
CAMK_PKD_PRKD1_ST	P02686	MBP	Q15139	PRKD1	S146	S141A	141	Missense	distal	-5	no	6.250	6.574	EPSD	COSMIC	4.507	Up-regulation
CAMK_PKD_PRKD1_ST	P02686	MBP	Q15139	PRKD1	T154	A158D	158	Missense	distal	4	no	4.763	4.791	EPSD	COSMIC	4.507	Up-regulation
CAMK_PKD_PRKD1_ST	P02686	MBP	Q15139	PRKD1	T154	A158V	158	Missense	distal	4	no	4.763	4.778	EPSD	COSMIC	4.507	Up-regulation
CAMK_PKD_PRKD1_ST	P02686	MBP	Q15139	PRKD1	T154	H157N	157	Missense	distal	3	no	4.763	4.751	EPSD	COSMIC	4.507	Down-regulation
CAMK_PKD_PRKD1_ST	P02686	MBP	Q15139	PRKD1	T154	R159G	159	Missense	distal	5	no	4.763	4.620	EPSD	COSMIC	4.507	Down-regulation
CAMK_PKD_PRKD1_ST	P02686	MBP	Q15139	PRKD1	S190	A185V	185	Missense	distal	-5	no	7.865	8.271	EPSD	COSMIC	4.507	Up-regulation
CAMK_PKD_PRKD1_ST	P02686	MBP	Q15139	PRKD1	S190	R183S	183	Missense	distal	-7	no	7.865	7.584	EPSD	COSMIC	4.507	Down-regulation
CAMK_PKD_PRKD1_ST	P02686	MBP	Q15139	PRKD1	S244	G238E	238	Missense	distal	-6	no	5.266	5.294	EPSD	COSMIC	4.507	Up-regulation
CAMK_PKD_PRKD1_ST	P02686	MBP	Q15139	PRKD1	S244	R241I	241	Missense	distal	-3	no	5.266	0.182	EPSD	COSMIC	4.507	Loss
CAMK_PKD_PRKD1_ST	P02686	MBP	Q15139	PRKD1	S244	W250C	250	Missense	distal	6	no	5.266	5.247	EPSD	COSMIC	4.507	Down-regulation
CAMK_PKD_PRKD1_ST	P02686	MBP	Q15139	PRKD1	S244	G240R	240	Missense	distal	-4	no	5.266	5.279	EPSD	COSMIC	4.507	Up-regulation
CAMK_PKD_PRKD1_ST	P02686	MBP	Q15139	PRKD1	S244	S244G	244	Missense	central	0	yes	5.266	0.000	EPSD	COSMIC	4.507	Loss
CAMK_PKD_PRKD1_ST	P02686	MBP	Q15139	PRKD1	S249	E253K	253	Missense	distal	4	no	4.940	4.939	EPSD	COSMIC	4.507	Down-regulation
CAMK_PKD_PRKD1_ST	P02686	MBP	Q15139	PRKD1	S249	G254C	254	Missense	distal	5	no	4.940	5.017	EPSD	COSMIC	4.507	Up-regulation
CAMK_PKD_PRKD1_ST	P02686	MBP	Q15139	PRKD1	S249	S244G	244	Missense	distal	-5	no	4.940	4.187	EPSD	COSMIC	4.507	Loss
CAMK_PKD_PRKD1_ST	P02686	MBP	Q15139	PRKD1	S295	S295G	295	Missense	central	0	yes	5.960	0.000	EPSD	COSMIC	4.507	Loss
CAMK_PKD_PRKD1_ST	P02686	MBP	Q15139	PRKD1	S295	K289M	289	Missense	distal	-6	no	5.960	5.957	EPSD	COSMIC	4.507	Down-regulation
CAMK_PKD_PRKD1_ST	P02686	MBP	Q15139	PRKD1	S299	S295G	295	Missense	distal	-4	no	6.592	6.583	EPSD	COSMIC	4.507	Down-regulation
CAMK_PKD_PRKD1_ST	P02686	MBP	Q15139	PRKD1	S299	R296P	296	Missense	distal	-3	no	6.592	2.676	EPSD	COSMIC	4.507	Loss
CAMK_PKD_PRKD1_ST	P02686	MBP	Q15139	PRKD1	S299	R296C	296	Missense	distal	-3	no	6.592	2.495	EPSD	COSMIC	4.507	Loss
CAMK_PKD_PRKD1_ST	P23528	CFL1	Q15139	PRKD1	S24	R21C	21	Missense	distal	-3	no	7.304	3.207	EPSD	COSMIC;GDSC;CCLE	4.507	Loss
CAMK_PKD_PRKD1_ST	P23528	CFL1	Q15139	PRKD1	S24	R21H	21	Missense	distal	-3	no	7.304	3.317	EPSD	COSMIC	4.507	Loss
CAMK_PKD_PRKD1_ST	P23528	CFL1	Q15139	PRKD1	S24	V29A	29	Missense	distal	5	no	7.304	7.386	EPSD	COSMIC	4.507	Up-regulation
CAMK_PKD_PRKD1_ST	P23528	CFL1	Q15139	PRKD1	S94	Y89N	89	Missense	distal	-5	no	3.649	4.653	EPSD	COSMIC	4.507	Gain
CAMK_PKD_PRKD1_ST	O95863	SNAI1	Q15139	PRKD1	S11	F5L	5	Missense	distal	-6	no	10.069	10.064	PhosphoSitePlus	COSMIC	4.507	Down-regulation
CAMK_PKD_PRKD1_ST	O95863	SNAI1	Q15139	PRKD1	T177	T177M	177	Missense	central	0	yes	6.165	0.000	EPSD	COSMIC	4.507	Loss
CAMK_PKD_PRKD1_ST	O95863	SNAI1	Q15139	PRKD1	T177	C180F	180	Missense	distal	3	no	6.165	6.148	EPSD	COSMIC	4.507	Down-regulation
CAMK_PKD_PRKD1_ST	O95863	SNAI1	Q15139	PRKD1	S246	H252Y	252	Missense	distal	6	no	6.585	6.626	EPSD	COSMIC	4.507	Up-regulation
CAMK_PKD_PRKD1_ST	O95863	SNAI1	Q15139	PRKD1	S246	S246F	246	Missense	central	0	yes	6.585	0.000	EPSD	COSMIC	4.507	Loss
CAMK_PKD_PRKD1_ST	P22059	OSBP	Q15139	PRKD1	T129	R131C	131	Missense	proximal	2	no	5.434	5.365	EPSD	COSMIC	4.507	Down-regulation
CAMK_PKD_PRKD1_ST	P22059	OSBP	Q15139	PRKD1	T129	E125Q	125	Missense	distal	-4	no	5.434	5.436	EPSD	COSMIC	4.507	Up-regulation
CAMK_PKD_PRKD1_ST	P22059	OSBP	Q15139	PRKD1	T129	E125G	125	Missense	distal	-4	no	5.434	5.427	EPSD	COSMIC	4.507	Down-regulation
CAMK_PKD_PRKD1_ST	P22059	OSBP	Q15139	PRKD1	T174	A175T	175	Missense	proximal	1	no	4.552	4.551	EPSD	COSMIC;CCLE	4.507	Down-regulation
CAMK_PKD_PRKD1_ST	P22059	OSBP	Q15139	PRKD1	S215	L211F	211	Missense	distal	-4	no	7.306	7.303	EPSD	COSMIC	4.507	Down-regulation
CAMK_PKD_PRKD1_ST	P22059	OSBP	Q15139	PRKD1	S216	L211F	211	Missense	distal	-5	no	4.528	1.376	EPSD	COSMIC	4.507	Loss
CAMK_PKD_PRKD1_ST	P22059	OSBP	Q15139	PRKD1	S240	K246T	246	Missense	distal	6	no	9.709	9.720	PhosphoSitePlus	COSMIC	4.507	Up-regulation
CAMK_PKD_PRKD1_ST	P22059	OSBP	Q15139	PRKD1	S287	L280F	280	Missense	distal	-7	no	4.452	4.596	EPSD	COSMIC	4.507	Gain
CAMK_PKD_PRKD1_ST	P22059	OSBP	Q15139	PRKD1	S287	Q284H	284	Missense	distal	-3	no	4.452	4.877	EPSD	COSMIC	4.507	Gain
CAMK_PKD_PRKD1_ST	P22059	OSBP	Q15139	PRKD1	T377	R376C	376	Missense	proximal	-1	no	4.972	4.779	EPSD	COSMIC;GDSC	4.507	Down-regulation
CAMK_PKD_PRKD1_ST	P22059	OSBP	Q15139	PRKD1	S379	R376C	376	Missense	distal	-3	no	6.164	2.067	EPSD	COSMIC;GDSC	4.507	Loss
CAMK_PKD_PRKD1_ST	P22059	OSBP	Q15139	PRKD1	T628	R621Q	621	Missense	distal	-7	no	7.439	7.164	EPSD	COSMIC	4.507	Down-regulation
CAMK_PKD_PRKD1_ST	P50552	VASP	Q15139	PRKD1	S255	P248A	248	Missense	distal	-7	no	4.550	4.754	EPSD	COSMIC	4.507	Up-regulation
CAMK_PKD_PRKD1_ST	P50552	VASP	Q15139	PRKD1	S255	G259A	259	Missense	distal	4	no	4.550	4.516	EPSD	COSMIC	4.507	Down-regulation
CAMK_PKD_PRKD1_ST	P50552	VASP	Q15139	PRKD1	S322	S325L	325	Missense	distal	3	no	9.307	9.299	EPSD;PhosphoSitePlus	COSMIC	4.507	Down-regulation
CAMK_PKD_PRKD1_ST	P50552	VASP	Q15139	PRKD1	S322	K321E	321	Missense	proximal	-1	no	9.307	9.263	EPSD;PhosphoSitePlus	COSMIC	4.507	Down-regulation
CAMK_PKD_PRKD1_ST	P50552	VASP	Q15139	PRKD1	S324	S325L	325	Missense	proximal	1	no	5.019	5.018	EPSD	COSMIC	4.507	Down-regulation
CAMK_PKD_PRKD1_ST	P50552	VASP	Q15139	PRKD1	S324	K321E	321	Missense	distal	-3	no	5.019	3.568	EPSD	COSMIC	4.507	Loss
CAMK_PKD_PRKD1_ST	O14558	HSPB6	Q15139	PRKD1	S16	S23L	23	Missense	distal	7	no	9.978	9.977	PhosphoSitePlus	COSMIC	4.507	Down-regulation
CAMK_PKD_PRKD1_ST	O14558	HSPB6	Q15139	PRKD1	S16	P20L	20	Missense	distal	4	no	9.978	9.975	PhosphoSitePlus	COSMIC	4.507	Down-regulation
CAMK_PKD_PRKD1_ST	O14558	HSPB6	Q15139	PRKD1	S16	S10F	10	Missense	distal	-6	no	9.978	9.949	PhosphoSitePlus	COSMIC;GDSC	4.507	Down-regulation
CAMK_PKD_PRKD1_ST	Q92918	MAP4K1	Q15139	PRKD1	S171	G174W	174	Missense	distal	3	no	12.724	12.727	PhosphoSitePlus	COSMIC	4.507	Up-regulation
CAMK_PKD_PRKD1_ST	Q92918	MAP4K1	Q15139	PRKD1	S320	P315S	315	Missense	distal	-5	no	4.490	5.072	EPSD	COSMIC	4.507	Gain
CAMK_PKD_PRKD1_ST	Q92918	MAP4K1	Q15139	PRKD1	S324	R319L	319	Missense	distal	-5	no	3.988	5.868	EPSD	COSMIC	4.507	Gain
CAMK_PKD_PRKD1_ST	Q92918	MAP4K1	Q15139	PRKD1	S325	P330L	330	Missense	distal	5	no	4.519	4.508	EPSD	COSMIC	4.507	Down-regulation
CAMK_PKD_PRKD1_ST	Q92918	MAP4K1	Q15139	PRKD1	S325	R323L	323	Missense	proximal	-2	no	4.519	1.411	EPSD	COSMIC	4.507	Loss
CAMK_PKD_PRKD1_ST	Q92918	MAP4K1	Q15139	PRKD1	S325	G328E	328	Missense	distal	3	no	4.519	4.538	EPSD	COSMIC	4.507	Up-regulation
CAMK_PKD_PRKD1_ST	Q92918	MAP4K1	Q15139	PRKD1	S325	R319L	319	Missense	distal	-6	no	4.519	4.481	EPSD	COSMIC	4.507	Loss
CAMK_PKD_PRKD1_ST	Q92918	MAP4K1	Q15139	PRKD1	S326	D333H	333	Missense	distal	7	no	6.803	6.804	EPSD	COSMIC	4.507	Up-regulation
CAMK_PKD_PRKD1_ST	Q92918	MAP4K1	Q15139	PRKD1	S326	P330L	330	Missense	distal	4	no	6.803	6.800	EPSD	COSMIC	4.507	Down-regulation
CAMK_PKD_PRKD1_ST	Q92918	MAP4K1	Q15139	PRKD1	S326	R323L	323	Missense	distal	-3	no	6.803	1.876	EPSD	COSMIC	4.507	Loss
CAMK_PKD_PRKD1_ST	Q92918	MAP4K1	Q15139	PRKD1	S326	G328E	328	Missense	proximal	2	no	6.803	6.913	EPSD	COSMIC	4.507	Up-regulation
CAMK_PKD_PRKD1_ST	Q92918	MAP4K1	Q15139	PRKD1	S326	R319L	319	Missense	distal	-7	no	6.803	5.998	EPSD	COSMIC	4.507	Down-regulation
CAMK_PKD_PRKD1_ST	Q92918	MAP4K1	Q15139	PRKD1	S368	P361S	361	Missense	distal	-7	no	7.175	7.288	EPSD	COSMIC	4.507	Up-regulation
CAMK_PKD_PRKD1_ST	Q92918	MAP4K1	Q15139	PRKD1	S374	P369L	369	Missense	distal	-5	no	3.941	6.786	EPSD	COSMIC	4.507	Gain
CAMK_PKD_PRKD1_ST	Q92918	MAP4K1	Q15139	PRKD1	S407	G410S	410	Missense	distal	3	no	6.713	6.739	EPSD	COSMIC	4.507	Up-regulation
CAMK_PKD_PRKD1_ST	Q92918	MAP4K1	Q15139	PRKD1	S454	H449Y	449	Missense	distal	-5	no	5.484	4.379	EPSD	COSMIC	4.507	Loss
CAMK_PKD_PRKD1_ST	Q92918	MAP4K1	Q15139	PRKD1	S737	P734R	734	Missense	distal	-3	no	3.584	7.500	EPSD	COSMIC	4.507	Gain
CAMK_PKD_PRKD1_ST	O00206	TLR4	Q15139	PRKD1	S790	R787C	787	Missense	distal	-3	no	8.857	4.760	PhosphoSitePlus	COSMIC	4.507	Down-regulation
CAMK_PKD_PRKD1_ST	O00206	TLR4	Q15139	PRKD1	S790	V783L	783	Missense	distal	-7	no	8.857	8.753	PhosphoSitePlus	COSMIC	4.507	Down-regulation
CAMK_PKD_PRKD1_ST	O00206	TLR4	Q15139	PRKD1	S790	L795M	795	Missense	distal	5	no	8.857	8.892	PhosphoSitePlus	COSMIC	4.507	Up-regulation
CAMK_PKD_PRKD1_ST	O00206	TLR4	Q15139	PRKD1	S790	L789P	789	Missense	proximal	-1	no	8.857	8.793	PhosphoSitePlus	COSMIC	4.507	Down-regulation
CAMK_PKD_PRKD1_ST	O00206	TLR4	Q15139	PRKD1	S790	L795Q	795	Missense	distal	5	no	8.857	8.912	PhosphoSitePlus	COSMIC	4.507	Up-regulation
CAMK_PKD_PRKD1_ST	O00206	TLR4	Q15139	PRKD1	S790	R787H	787	Missense	distal	-3	no	8.857	4.870	PhosphoSitePlus	COSMIC	4.507	Down-regulation
CAMK_PKD_PRKD1_ST	O00206	TLR4	Q15139	PRKD1	S790	N792I	792	Missense	proximal	2	no	8.857	8.856	PhosphoSitePlus	COSMIC	4.507	Down-regulation
CAMK_PKD_PRKD1_ST	P04792	HSPB1	Q15139	PRKD1	S15	P14S	14	Missense	proximal	-1	no	7.595	7.691	EPSD	COSMIC	4.507	Up-regulation
CAMK_PKD_PRKD1_ST	P04792	HSPB1	Q15139	PRKD1	S15	R20W	20	Missense	distal	5	no	7.595	7.476	EPSD	COSMIC	4.507	Down-regulation
CAMK_PKD_PRKD1_ST	P04792	HSPB1	Q15139	PRKD1	S15	R20Q	20	Missense	distal	5	no	7.595	7.572	EPSD	COSMIC	4.507	Down-regulation
CAMK_PKD_PRKD1_ST	P04792	HSPB1	Q15139	PRKD1	S15	F8L	8	Missense	distal	-7	no	7.595	7.451	EPSD	COSMIC	4.507	Down-regulation
CAMK_PKD_PRKD1_ST	P04792	HSPB1	Q15139	PRKD1	S43	S49G	49	Missense	distal	6	no	4.571	4.623	EPSD	COSMIC;CCLE	4.507	Up-regulation
CAMK_PKD_PRKD1_ST	P04792	HSPB1	Q15139	PRKD1	S43	S43L	43	Missense	central	0	yes	4.571	0.000	EPSD	COSMIC	4.507	Loss
CAMK_PKD_PRKD1_ST	P04792	HSPB1	Q15139	PRKD1	S78	R75C	75	Missense	distal	-3	no	7.008	2.911	EPSD	COSMIC	4.507	Loss
CAMK_PKD_PRKD1_ST	P04792	HSPB1	Q15139	PRKD1	S82	R75C	75	Missense	distal	-7	no	10.184	9.731	PhosphoSitePlus	COSMIC	4.507	Down-regulation
CAMK_PKD_PRKD1_ST	P04792	HSPB1	Q15139	PRKD1	T143	R140Q	140	Missense	distal	-3	no	5.806	1.394	EPSD	COSMIC	4.507	Loss
CAMK_PKD_PRKD1_ST	P04792	HSPB1	Q15139	PRKD1	S158	T151A	151	Missense	distal	-7	no	4.483	4.743	EPSD	COSMIC;GDSC;CCLE	4.507	Gain
TK_PDGFR_KIT_Y	P10721	KIT	P10721	KIT	Y547	E554K	554	Missense	distal	7	no	3.906	3.923	EPSD;PhosphoSitePlus	COSMIC	1.639	Up-regulation
TK_PDGFR_KIT_Y	P10721	KIT	P10721	KIT	Y547	P551L	551	Missense	distal	4	no	3.906	3.655	EPSD;PhosphoSitePlus	COSMIC	1.639	Down-regulation
TK_PDGFR_KIT_Y	P10721	KIT	P10721	KIT	Y547	K546R	546	Missense	proximal	-1	no	3.906	3.941	EPSD;PhosphoSitePlus	COSMIC	1.639	Up-regulation
TK_PDGFR_KIT_Y	P10721	KIT	P10721	KIT	Y547	Y553C	553	Missense	distal	6	no	3.906	3.943	EPSD;PhosphoSitePlus	COSMIC	1.639	Up-regulation
TK_PDGFR_KIT_Y	P10721	KIT	P10721	KIT	Y547	P551S	551	Missense	distal	4	no	3.906	3.532	EPSD;PhosphoSitePlus	COSMIC	1.639	Down-regulation
TK_PDGFR_KIT_Y	P10721	KIT	P10721	KIT	Y547	Y547N	547	Missense	central	0	yes	3.906	0.000	EPSD;PhosphoSitePlus	COSMIC	1.639	Loss
TK_PDGFR_KIT_Y	P10721	KIT	P10721	KIT	Y547	P551A	551	Missense	distal	4	no	3.906	3.540	EPSD;PhosphoSitePlus	COSMIC	1.639	Down-regulation
TK_PDGFR_KIT_Y	P10721	KIT	P10721	KIT	Y547	M552T	552	Missense	distal	5	no	3.906	3.895	EPSD;PhosphoSitePlus	COSMIC	1.639	Down-regulation
TK_PDGFR_KIT_Y	P10721	KIT	P10721	KIT	Y547	K550I	550	Missense	distal	3	no	3.906	3.952	EPSD;PhosphoSitePlus	COSMIC	1.639	Up-regulation
TK_PDGFR_KIT_Y	P10721	KIT	P10721	KIT	Y547	Y553N	553	Missense	distal	6	no	3.906	3.897	EPSD;PhosphoSitePlus	COSMIC	1.639	Down-regulation
TK_PDGFR_KIT_Y	P10721	KIT	P10721	KIT	Y547	K550N	550	Missense	distal	3	no	3.906	3.934	EPSD;PhosphoSitePlus	COSMIC	1.639	Up-regulation
TK_PDGFR_KIT_Y	P10721	KIT	P10721	KIT	Y547	M552I	552	Missense	distal	5	no	3.906	3.922	EPSD;PhosphoSitePlus	COSMIC	1.639	Up-regulation
TK_PDGFR_KIT_Y	P10721	KIT	P10721	KIT	Y547	P551T	551	Missense	distal	4	no	3.906	3.317	EPSD;PhosphoSitePlus	COSMIC	1.639	Down-regulation
TK_PDGFR_KIT_Y	P10721	KIT	P10721	KIT	Y547	E554A	554	Missense	distal	7	no	3.906	3.921	EPSD;PhosphoSitePlus	COSMIC	1.639	Up-regulation
TK_PDGFR_KIT_Y	P10721	KIT	P10721	KIT	Y547	K550R	550	Missense	distal	3	no	3.906	3.933	EPSD;PhosphoSitePlus	COSMIC	1.639	Up-regulation
TK_PDGFR_KIT_Y	P10721	KIT	P10721	KIT	Y547	M552V	552	Missense	distal	5	no	3.906	3.911	EPSD;PhosphoSitePlus	COSMIC	1.639	Up-regulation
TK_PDGFR_KIT_Y	P10721	KIT	P10721	KIT	Y547	I542T	542	Missense	distal	-5	no	3.906	3.348	EPSD;PhosphoSitePlus	COSMIC	1.639	Down-regulation
TK_PDGFR_KIT_Y	P10721	KIT	P10721	KIT	Y547	Y553S	553	Missense	distal	6	no	3.906	3.938	EPSD;PhosphoSitePlus	COSMIC	1.639	Up-regulation
TK_PDGFR_KIT_Y	P10721	KIT	P10721	KIT	Y547	E554D	554	Missense	distal	7	no	3.906	3.878	EPSD;PhosphoSitePlus	COSMIC	1.639	Down-regulation
TK_PDGFR_KIT_Y	P10721	KIT	P10721	KIT	Y547	P551R	551	Missense	distal	4	no	3.906	3.538	EPSD;PhosphoSitePlus	COSMIC	1.639	Down-regulation
TK_PDGFR_KIT_Y	P10721	KIT	P10721	KIT	Y547	V540L	540	Missense	distal	-7	no	3.906	3.940	EPSD;PhosphoSitePlus	COSMIC	1.639	Up-regulation
TK_PDGFR_KIT_Y	P10721	KIT	P10721	KIT	Y547	M541I	541	Missense	distal	-6	no	3.906	4.129	EPSD;PhosphoSitePlus	COSMIC	1.639	Up-regulation
TK_PDGFR_KIT_Y	P10721	KIT	P10721	KIT	Y547	E554G	554	Missense	distal	7	no	3.906	3.837	EPSD;PhosphoSitePlus	COSMIC	1.639	Down-regulation
TK_PDGFR_KIT_Y	P10721	KIT	P10721	KIT	Y547	M552K	552	Missense	distal	5	no	3.906	3.895	EPSD;PhosphoSitePlus	COSMIC	1.639	Down-regulation
TK_PDGFR_KIT_Y	P10721	KIT	P10721	KIT	Y547	Y553V	553	Missense	distal	6	no	3.906	3.980	EPSD;PhosphoSitePlus	COSMIC	1.639	Up-regulation
TK_PDGFR_KIT_Y	P10721	KIT	P10721	KIT	Y553	V559P	559	Missense	distal	6	no	3.485	3.345	PhosphoSitePlus;EPSD	COSMIC	1.639	Down-regulation
TK_PDGFR_KIT_Y	P10721	KIT	P10721	KIT	Y553	V559D	559	Missense	distal	6	no	3.485	3.339	PhosphoSitePlus;EPSD	COSMIC	1.639	Down-regulation
TK_PDGFR_KIT_Y	P10721	KIT	P10721	KIT	Y553	E554K	554	Missense	proximal	1	no	3.485	3.553	PhosphoSitePlus;EPSD	COSMIC	1.639	Up-regulation
TK_PDGFR_KIT_Y	P10721	KIT	P10721	KIT	Y553	P551L	551	Missense	proximal	-2	no	3.485	3.479	PhosphoSitePlus;EPSD	COSMIC	1.639	Down-regulation
TK_PDGFR_KIT_Y	P10721	KIT	P10721	KIT	Y553	K546R	546	Missense	distal	-7	no	3.485	3.436	PhosphoSitePlus;EPSD	COSMIC	1.639	Down-regulation
TK_PDGFR_KIT_Y	P10721	KIT	P10721	KIT	Y553	Y553C	553	Missense	central	0	yes	3.485	0.000	PhosphoSitePlus;EPSD	COSMIC	1.639	Loss
TK_PDGFR_KIT_Y	P10721	KIT	P10721	KIT	Y553	V559I	559	Missense	distal	6	no	3.485	3.380	PhosphoSitePlus;EPSD	COSMIC	1.639	Down-regulation
TK_PDGFR_KIT_Y	P10721	KIT	P10721	KIT	Y553	W557X	557	Missense	distal	4	no	3.485	3.364	PhosphoSitePlus;EPSD	COSMIC	1.639	Down-regulation
TK_PDGFR_KIT_Y	P10721	KIT	P10721	KIT	Y553	V559X	559	Missense	distal	6	no	3.485	3.410	PhosphoSitePlus;EPSD	COSMIC	1.639	Down-regulation
TK_PDGFR_KIT_Y	P10721	KIT	P10721	KIT	Y553	P551S	551	Missense	proximal	-2	no	3.485	3.488	PhosphoSitePlus;EPSD	COSMIC	1.639	Up-regulation
TK_PDGFR_KIT_Y	P10721	KIT	P10721	KIT	Y553	V560G	560	Missense	distal	7	no	3.485	3.415	PhosphoSitePlus;EPSD	COSMIC	1.639	Down-regulation
TK_PDGFR_KIT_Y	P10721	KIT	P10721	KIT	Y553	Y547N	547	Missense	distal	-6	no	3.485	3.399	PhosphoSitePlus;EPSD	COSMIC	1.639	Down-regulation
TK_PDGFR_KIT_Y	P10721	KIT	P10721	KIT	Y553	Q556L	556	Missense	distal	3	no	3.485	3.466	PhosphoSitePlus;EPSD	COSMIC	1.639	Down-regulation
TK_PDGFR_KIT_Y	P10721	KIT	P10721	KIT	Y553	V560A	560	Missense	distal	7	no	3.485	3.500	PhosphoSitePlus;EPSD	COSMIC	1.639	Up-regulation
TK_PDGFR_KIT_Y	P10721	KIT	P10721	KIT	Y553	W557S	557	Missense	distal	4	no	3.485	3.448	PhosphoSitePlus;EPSD	COSMIC	1.639	Down-regulation
TK_PDGFR_KIT_Y	P10721	KIT	P10721	KIT	Y553	P551A	551	Missense	proximal	-2	no	3.485	3.483	PhosphoSitePlus;EPSD	COSMIC	1.639	Down-regulation
TK_PDGFR_KIT_Y	P10721	KIT	P10721	KIT	Y553	M552T	552	Missense	proximal	-1	no	3.485	3.383	PhosphoSitePlus;EPSD	COSMIC	1.639	Down-regulation
TK_PDGFR_KIT_Y	P10721	KIT	P10721	KIT	Y553	V555I	555	Missense	proximal	2	no	3.485	3.480	PhosphoSitePlus;EPSD	COSMIC	1.639	Down-regulation
TK_PDGFR_KIT_Y	P10721	KIT	P10721	KIT	Y553	K550I	550	Missense	distal	-3	no	3.485	3.433	PhosphoSitePlus;EPSD	COSMIC	1.639	Down-regulation
TK_PDGFR_KIT_Y	P10721	KIT	P10721	KIT	Y553	Y553N	553	Missense	central	0	yes	3.485	0.000	PhosphoSitePlus;EPSD	COSMIC	1.639	Loss
TK_PDGFR_KIT_Y	P10721	KIT	P10721	KIT	Y553	K550N	550	Missense	distal	-3	no	3.485	3.564	PhosphoSitePlus;EPSD	COSMIC	1.639	Up-regulation
TK_PDGFR_KIT_Y	P10721	KIT	P10721	KIT	Y553	M552I	552	Missense	proximal	-1	no	3.485	3.480	PhosphoSitePlus;EPSD	COSMIC	1.639	Down-regulation
TK_PDGFR_KIT_Y	P10721	KIT	P10721	KIT	Y553	V559F	559	Missense	distal	6	no	3.485	3.412	PhosphoSitePlus;EPSD	COSMIC	1.639	Down-regulation
TK_PDGFR_KIT_Y	P10721	KIT	P10721	KIT	Y553	P551T	551	Missense	proximal	-2	no	3.485	3.484	PhosphoSitePlus;EPSD	COSMIC	1.639	Down-regulation
TK_PDGFR_KIT_Y	P10721	KIT	P10721	KIT	Y553	E554A	554	Missense	proximal	1	no	3.485	3.519	PhosphoSitePlus;EPSD	COSMIC	1.639	Up-regulation
TK_PDGFR_KIT_Y	P10721	KIT	P10721	KIT	Y553	V555L	555	Missense	proximal	2	no	3.485	3.479	PhosphoSitePlus;EPSD	COSMIC	1.639	Down-regulation
TK_PDGFR_KIT_Y	P10721	KIT	P10721	KIT	Y553	V555E	555	Missense	proximal	2	no	3.485	3.463	PhosphoSitePlus;EPSD	COSMIC	1.639	Down-regulation
TK_PDGFR_KIT_Y	P10721	KIT	P10721	KIT	Y553	K558R	558	Missense	distal	5	no	3.485	3.481	PhosphoSitePlus;EPSD	COSMIC	1.639	Down-regulation
TK_PDGFR_KIT_Y	P10721	KIT	P10721	KIT	Y553	K558Q	558	Missense	distal	5	no	3.485	3.490	PhosphoSitePlus;EPSD	COSMIC	1.639	Up-regulation
TK_PDGFR_KIT_Y	P10721	KIT	P10721	KIT	Y553	K550R	550	Missense	distal	-3	no	3.485	3.538	PhosphoSitePlus;EPSD	COSMIC	1.639	Up-regulation
TK_PDGFR_KIT_Y	P10721	KIT	P10721	KIT	Y553	K558A	558	Missense	distal	5	no	3.485	3.495	PhosphoSitePlus;EPSD	COSMIC	1.639	Up-regulation
TK_PDGFR_KIT_Y	P10721	KIT	P10721	KIT	Y553	M552V	552	Missense	proximal	-1	no	3.485	3.443	PhosphoSitePlus;EPSD	COSMIC	1.639	Down-regulation
TK_PDGFR_KIT_Y	P10721	KIT	P10721	KIT	Y553	Y553S	553	Missense	central	0	yes	3.485	0.000	PhosphoSitePlus;EPSD	COSMIC	1.639	Loss
TK_PDGFR_KIT_Y	P10721	KIT	P10721	KIT	Y553	E554D	554	Missense	proximal	1	no	3.485	3.251	PhosphoSitePlus;EPSD	COSMIC	1.639	Down-regulation
TK_PDGFR_KIT_Y	P10721	KIT	P10721	KIT	Y553	V559K	559	Missense	distal	6	no	3.485	3.382	PhosphoSitePlus;EPSD	COSMIC	1.639	Down-regulation
TK_PDGFR_KIT_Y	P10721	KIT	P10721	KIT	Y553	P551R	551	Missense	proximal	-2	no	3.485	3.483	PhosphoSitePlus;EPSD	COSMIC	1.639	Down-regulation
TK_PDGFR_KIT_Y	P10721	KIT	P10721	KIT	Y553	W557F	557	Missense	distal	4	no	3.485	3.474	PhosphoSitePlus;EPSD	COSMIC	1.639	Down-regulation
TK_PDGFR_KIT_Y	P10721	KIT	P10721	KIT	Y553	Q556H	556	Missense	distal	3	no	3.485	3.481	PhosphoSitePlus;EPSD	COSMIC	1.639	Down-regulation
TK_PDGFR_KIT_Y	P10721	KIT	P10721	KIT	Y553	Q556R	556	Missense	distal	3	no	3.485	3.476	PhosphoSitePlus;EPSD	COSMIC	1.639	Down-regulation
TK_PDGFR_KIT_Y	P10721	KIT	P10721	KIT	Y553	E554G	554	Missense	proximal	1	no	3.485	3.352	PhosphoSitePlus;EPSD	COSMIC	1.639	Down-regulation
TK_PDGFR_KIT_Y	P10721	KIT	P10721	KIT	Y553	V559C	559	Missense	distal	6	no	3.485	3.448	PhosphoSitePlus;EPSD	COSMIC	1.639	Down-regulation
TK_PDGFR_KIT_Y	P10721	KIT	P10721	KIT	Y553	M552K	552	Missense	proximal	-1	no	3.485	3.369	PhosphoSitePlus;EPSD	COSMIC	1.639	Down-regulation
TK_PDGFR_KIT_Y	P10721	KIT	P10721	KIT	Y553	Y553V	553	Missense	central	0	yes	3.485	0.000	PhosphoSitePlus;EPSD	COSMIC	1.639	Loss
TK_PDGFR_KIT_Y	P10721	KIT	P10721	KIT	Y553	Q556P	556	Missense	distal	3	no	3.485	3.495	PhosphoSitePlus;EPSD	COSMIC	1.639	Up-regulation
TK_PDGFR_KIT_Y	P10721	KIT	P10721	KIT	Y568	E562V	562	Missense	distal	-6	no	3.400	3.324	EPSD;PhosphoSitePlus	COSMIC	1.639	Down-regulation
TK_PDGFR_KIT_Y	P10721	KIT	P10721	KIT	Y568	Y568C	568	Missense	central	0	yes	3.400	0.000	EPSD;PhosphoSitePlus	COSMIC	1.639	Loss
TK_PDGFR_KIT_Y	P10721	KIT	P10721	KIT	Y568	E561D	561	Missense	distal	-7	no	3.400	3.473	EPSD;PhosphoSitePlus	COSMIC	1.639	Up-regulation
TK_PDGFR_KIT_Y	P10721	KIT	P10721	KIT	Y568	N567H	567	Missense	proximal	-1	no	3.400	3.450	EPSD;PhosphoSitePlus	COSMIC	1.639	Up-regulation
TK_PDGFR_KIT_Y	P10721	KIT	P10721	KIT	Y568	E561K	561	Missense	distal	-7	no	3.400	3.470	EPSD;PhosphoSitePlus	COSMIC	1.639	Up-regulation
TK_PDGFR_KIT_Y	P10721	KIT	P10721	KIT	Y568	D572N	572	Missense	distal	4	no	3.400	2.757	EPSD;PhosphoSitePlus	COSMIC	1.639	Down-regulation
TK_PDGFR_KIT_Y	P10721	KIT	P10721	KIT	Y568	E562D	562	Missense	distal	-6	no	3.400	3.378	EPSD;PhosphoSitePlus	COSMIC	1.639	Down-regulation
TK_PDGFR_KIT_Y	P10721	KIT	P10721	KIT	Y568	N566S	566	Missense	proximal	-2	no	3.400	3.403	EPSD;PhosphoSitePlus	COSMIC	1.639	Up-regulation
TK_PDGFR_KIT_Y	P10721	KIT	P10721	KIT	Y568	E562K	562	Missense	distal	-6	no	3.400	3.298	EPSD;PhosphoSitePlus	COSMIC	1.639	Down-regulation
TK_PDGFR_KIT_Y	P10721	KIT	P10721	KIT	Y568	N564H	564	Missense	distal	-4	no	3.400	3.277	EPSD;PhosphoSitePlus	COSMIC	1.639	Down-regulation
TK_PDGFR_KIT_Y	P10721	KIT	P10721	KIT	Y568	I563V	563	Missense	distal	-5	no	3.400	2.735	EPSD;PhosphoSitePlus	COSMIC	1.639	Down-regulation
TK_PDGFR_KIT_Y	P10721	KIT	P10721	KIT	Y568	E562Q	562	Missense	distal	-6	no	3.400	3.224	EPSD;PhosphoSitePlus	COSMIC	1.639	Down-regulation
TK_PDGFR_KIT_Y	P10721	KIT	P10721	KIT	Y568	Q575H	575	Missense	distal	7	no	3.400	3.321	EPSD;PhosphoSitePlus	COSMIC	1.639	Down-regulation
TK_PDGFR_KIT_Y	P10721	KIT	P10721	KIT	Y568	I571V	571	Missense	distal	3	no	3.400	3.368	EPSD;PhosphoSitePlus	COSMIC	1.639	Down-regulation
TK_PDGFR_KIT_Y	P10721	KIT	P10721	KIT	Y568	D572G	572	Missense	distal	4	no	3.400	3.178	EPSD;PhosphoSitePlus	COSMIC	1.639	Down-regulation
TK_PDGFR_KIT_Y	P10721	KIT	P10721	KIT	Y568	T574P	574	Missense	distal	6	no	3.400	3.296	EPSD;PhosphoSitePlus	COSMIC	1.639	Down-regulation
TK_PDGFR_KIT_Y	P10721	KIT	P10721	KIT	Y568	N567K	567	Missense	proximal	-1	no	3.400	3.309	EPSD;PhosphoSitePlus	COSMIC	1.639	Down-regulation
TK_PDGFR_KIT_Y	P10721	KIT	P10721	KIT	Y568	Y570D	570	Missense	proximal	2	no	3.400	3.396	EPSD;PhosphoSitePlus	COSMIC	1.639	Down-regulation
TK_PDGFR_KIT_Y	P10721	KIT	P10721	KIT	Y568	I571R	571	Missense	distal	3	no	3.400	3.381	EPSD;PhosphoSitePlus	COSMIC	1.639	Down-regulation
TK_PDGFR_KIT_Y	P10721	KIT	P10721	KIT	Y568	P573R	573	Missense	distal	5	no	3.400	3.401	EPSD;PhosphoSitePlus	COSMIC	1.639	Up-regulation
TK_PDGFR_KIT_Y	P10721	KIT	P10721	KIT	Y568	D572Y	572	Missense	distal	4	no	3.400	2.996	EPSD;PhosphoSitePlus	COSMIC	1.639	Down-regulation
TK_PDGFR_KIT_Y	P10721	KIT	P10721	KIT	Y568	N564S	564	Missense	distal	-4	no	3.400	3.453	EPSD;PhosphoSitePlus	COSMIC	1.639	Up-regulation
TK_PDGFR_KIT_Y	P10721	KIT	P10721	KIT	Y568	N564K	564	Missense	distal	-4	no	3.400	3.329	EPSD;PhosphoSitePlus	COSMIC	1.639	Down-regulation
TK_PDGFR_KIT_Y	P10721	KIT	P10721	KIT	Y568	Y570F	570	Missense	proximal	2	no	3.400	3.407	EPSD;PhosphoSitePlus	COSMIC	1.639	Up-regulation
TK_PDGFR_KIT_Y	P10721	KIT	P10721	KIT	Y568	N566D	566	Missense	proximal	-2	no	3.400	3.399	EPSD;PhosphoSitePlus	COSMIC	1.639	Down-regulation
TK_PDGFR_KIT_Y	P10721	KIT	P10721	KIT	Y568	E562A	562	Missense	distal	-6	no	3.400	3.323	EPSD;PhosphoSitePlus	COSMIC	1.639	Down-regulation
TK_PDGFR_KIT_Y	P10721	KIT	P10721	KIT	Y568	E561G	561	Missense	distal	-7	no	3.400	3.574	EPSD;PhosphoSitePlus	COSMIC	1.639	Up-regulation
TK_PDGFR_KIT_Y	P10721	KIT	P10721	KIT	Y568	N566Y	566	Missense	proximal	-2	no	3.400	3.398	EPSD;PhosphoSitePlus	COSMIC	1.639	Down-regulation
TK_PDGFR_KIT_Y	P10721	KIT	P10721	KIT	Y568	V569A	569	Missense	proximal	1	no	3.400	3.258	EPSD;PhosphoSitePlus	COSMIC	1.639	Down-regulation
TK_PDGFR_KIT_Y	P10721	KIT	P10721	KIT	Y568	I571K	571	Missense	distal	3	no	3.400	3.354	EPSD;PhosphoSitePlus	COSMIC	1.639	Down-regulation
TK_PDGFR_KIT_Y	P10721	KIT	P10721	KIT	Y568	N567S	567	Missense	proximal	-1	no	3.400	3.295	EPSD;PhosphoSitePlus	COSMIC	1.639	Down-regulation
TK_PDGFR_KIT_Y	P10721	KIT	P10721	KIT	Y568	G565R	565	Missense	distal	-3	no	3.400	3.441	EPSD;PhosphoSitePlus	COSMIC	1.639	Up-regulation
TK_PDGFR_KIT_Y	P10721	KIT	P10721	KIT	Y568	Y568D	568	Missense	central	0	yes	3.400	0.000	EPSD;PhosphoSitePlus	COSMIC	1.639	Loss
TK_PDGFR_KIT_Y	P10721	KIT	P10721	KIT	Y568	I571M	571	Missense	distal	3	no	3.400	3.373	EPSD;PhosphoSitePlus	COSMIC	1.639	Down-regulation
TK_PDGFR_KIT_Y	P10721	KIT	P10721	KIT	Y568	E561Q	561	Missense	distal	-7	no	3.400	3.392	EPSD;PhosphoSitePlus	COSMIC	1.639	Down-regulation
TK_PDGFR_KIT_Y	P10721	KIT	P10721	KIT	Y568	T574I	574	Missense	distal	6	no	3.400	3.332	EPSD;PhosphoSitePlus	COSMIC	1.639	Down-regulation
TK_PDGFR_KIT_Y	P10721	KIT	P10721	KIT	Y568	I563L	563	Missense	distal	-5	no	3.400	3.084	EPSD;PhosphoSitePlus	COSMIC	1.639	Down-regulation
TK_PDGFR_KIT_Y	P10721	KIT	P10721	KIT	Y568	D572E	572	Missense	distal	4	no	3.400	2.632	EPSD;PhosphoSitePlus	COSMIC	1.639	Down-regulation
TK_PDGFR_KIT_Y	P10721	KIT	P10721	KIT	Y568	V569G	569	Missense	proximal	1	no	3.400	3.091	EPSD;PhosphoSitePlus	COSMIC	1.639	Down-regulation
TK_PDGFR_KIT_Y	P10721	KIT	P10721	KIT	Y568	G565V	565	Missense	distal	-3	no	3.400	3.396	EPSD;PhosphoSitePlus	COSMIC	1.639	Down-regulation
TK_PDGFR_KIT_Y	P10721	KIT	P10721	KIT	Y568	V569I	569	Missense	proximal	1	no	3.400	3.284	EPSD;PhosphoSitePlus	COSMIC	1.639	Down-regulation
TK_PDGFR_KIT_Y	P10721	KIT	P10721	KIT	Y568	N566T	566	Missense	proximal	-2	no	3.400	3.399	EPSD;PhosphoSitePlus	COSMIC	1.639	Down-regulation
TK_PDGFR_KIT_Y	P10721	KIT	P10721	KIT	Y568	D572A	572	Missense	distal	4	no	3.400	2.967	EPSD;PhosphoSitePlus	COSMIC	1.639	Down-regulation
TK_PDGFR_KIT_Y	P10721	KIT	P10721	KIT	Y568	G565E	565	Missense	distal	-3	no	3.400	3.480	EPSD;PhosphoSitePlus	COSMIC	1.639	Up-regulation
TK_PDGFR_KIT_Y	P10721	KIT	P10721	KIT	Y568	V569D	569	Missense	proximal	1	no	3.400	2.989	EPSD;PhosphoSitePlus	COSMIC	1.639	Down-regulation
TK_PDGFR_KIT_Y	P10721	KIT	P10721	KIT	Y568	I571L	571	Missense	distal	3	no	3.400	3.372	EPSD;PhosphoSitePlus	COSMIC	1.639	Down-regulation
TK_PDGFR_KIT_Y	P10721	KIT	P10721	KIT	Y570	L576F	576	Missense	distal	6	no	3.527	3.521	EPSD;PhosphoSitePlus	COSMIC	1.639	Down-regulation
TK_PDGFR_KIT_Y	P10721	KIT	P10721	KIT	Y570	Y568C	568	Missense	proximal	-2	no	3.527	3.525	EPSD;PhosphoSitePlus	COSMIC	1.639	Down-regulation
TK_PDGFR_KIT_Y	P10721	KIT	P10721	KIT	Y570	N567H	567	Missense	distal	-3	no	3.527	3.464	EPSD;PhosphoSitePlus	COSMIC	1.639	Down-regulation
TK_PDGFR_KIT_Y	P10721	KIT	P10721	KIT	Y570	L576R	576	Missense	distal	6	no	3.527	3.500	EPSD;PhosphoSitePlus	COSMIC	1.639	Down-regulation
TK_PDGFR_KIT_Y	P10721	KIT	P10721	KIT	Y570	D572N	572	Missense	proximal	2	no	3.527	3.535	EPSD;PhosphoSitePlus	COSMIC	1.639	Up-regulation
TK_PDGFR_KIT_Y	P10721	KIT	P10721	KIT	Y570	N566S	566	Missense	distal	-4	no	3.527	3.580	EPSD;PhosphoSitePlus	COSMIC	1.639	Up-regulation
TK_PDGFR_KIT_Y	P10721	KIT	P10721	KIT	Y570	N564H	564	Missense	distal	-6	no	3.527	3.689	EPSD;PhosphoSitePlus	COSMIC	1.639	Up-regulation
TK_PDGFR_KIT_Y	P10721	KIT	P10721	KIT	Y570	P577S	577	Missense	distal	7	no	3.527	3.561	EPSD;PhosphoSitePlus	COSMIC	1.639	Up-regulation
TK_PDGFR_KIT_Y	P10721	KIT	P10721	KIT	Y570	P577K	577	Missense	distal	7	no	3.527	3.537	EPSD;PhosphoSitePlus	COSMIC	1.639	Up-regulation
TK_PDGFR_KIT_Y	P10721	KIT	P10721	KIT	Y570	I563V	563	Missense	distal	-7	no	3.527	3.370	EPSD;PhosphoSitePlus	COSMIC	1.639	Down-regulation
TK_PDGFR_KIT_Y	P10721	KIT	P10721	KIT	Y570	Q575H	575	Missense	distal	5	no	3.527	3.534	EPSD;PhosphoSitePlus	COSMIC	1.639	Up-regulation
TK_PDGFR_KIT_Y	P10721	KIT	P10721	KIT	Y570	I571V	571	Missense	proximal	1	no	3.527	3.643	EPSD;PhosphoSitePlus	COSMIC	1.639	Up-regulation
TK_PDGFR_KIT_Y	P10721	KIT	P10721	KIT	Y570	D572G	572	Missense	proximal	2	no	3.527	3.545	EPSD;PhosphoSitePlus	COSMIC	1.639	Up-regulation
TK_PDGFR_KIT_Y	P10721	KIT	P10721	KIT	Y570	T574P	574	Missense	distal	4	no	3.527	4.117	EPSD;PhosphoSitePlus	COSMIC	1.639	Up-regulation
TK_PDGFR_KIT_Y	P10721	KIT	P10721	KIT	Y570	N567K	567	Missense	distal	-3	no	3.527	3.447	EPSD;PhosphoSitePlus	COSMIC	1.639	Down-regulation
TK_PDGFR_KIT_Y	P10721	KIT	P10721	KIT	Y570	Y570D	570	Missense	central	0	yes	3.527	0.000	EPSD;PhosphoSitePlus	COSMIC	1.639	Loss
TK_PDGFR_KIT_Y	P10721	KIT	P10721	KIT	Y570	I571R	571	Missense	proximal	1	no	3.527	3.453	EPSD;PhosphoSitePlus	COSMIC	1.639	Down-regulation
TK_PDGFR_KIT_Y	P10721	KIT	P10721	KIT	Y570	P573R	573	Missense	distal	3	no	3.527	3.508	EPSD;PhosphoSitePlus	COSMIC	1.639	Down-regulation
TK_PDGFR_KIT_Y	P10721	KIT	P10721	KIT	Y570	D572Y	572	Missense	proximal	2	no	3.527	3.531	EPSD;PhosphoSitePlus	COSMIC	1.639	Up-regulation
TK_PDGFR_KIT_Y	P10721	KIT	P10721	KIT	Y570	N564S	564	Missense	distal	-6	no	3.527	3.476	EPSD;PhosphoSitePlus	COSMIC	1.639	Down-regulation
TK_PDGFR_KIT_Y	P10721	KIT	P10721	KIT	Y570	N564K	564	Missense	distal	-6	no	3.527	3.519	EPSD;PhosphoSitePlus	COSMIC	1.639	Down-regulation
TK_PDGFR_KIT_Y	P10721	KIT	P10721	KIT	Y570	Y570F	570	Missense	central	0	yes	3.527	0.000	EPSD;PhosphoSitePlus	COSMIC	1.639	Loss
TK_PDGFR_KIT_Y	P10721	KIT	P10721	KIT	Y570	N566D	566	Missense	distal	-4	no	3.527	3.487	EPSD;PhosphoSitePlus	COSMIC	1.639	Down-regulation
TK_PDGFR_KIT_Y	P10721	KIT	P10721	KIT	Y570	N566Y	566	Missense	distal	-4	no	3.527	3.426	EPSD;PhosphoSitePlus	COSMIC	1.639	Down-regulation
TK_PDGFR_KIT_Y	P10721	KIT	P10721	KIT	Y570	V569A	569	Missense	proximal	-1	no	3.527	3.511	EPSD;PhosphoSitePlus	COSMIC	1.639	Down-regulation
TK_PDGFR_KIT_Y	P10721	KIT	P10721	KIT	Y570	I571K	571	Missense	proximal	1	no	3.527	3.534	EPSD;PhosphoSitePlus	COSMIC	1.639	Up-regulation
TK_PDGFR_KIT_Y	P10721	KIT	P10721	KIT	Y570	N567S	567	Missense	distal	-3	no	3.527	3.543	EPSD;PhosphoSitePlus	COSMIC	1.639	Up-regulation
TK_PDGFR_KIT_Y	P10721	KIT	P10721	KIT	Y570	G565R	565	Missense	distal	-5	no	3.527	3.223	EPSD;PhosphoSitePlus	COSMIC	1.639	Down-regulation
TK_PDGFR_KIT_Y	P10721	KIT	P10721	KIT	Y570	Y568D	568	Missense	proximal	-2	no	3.527	3.528	EPSD;PhosphoSitePlus	COSMIC	1.639	Up-regulation
TK_PDGFR_KIT_Y	P10721	KIT	P10721	KIT	Y570	I571M	571	Missense	proximal	1	no	3.527	3.557	EPSD;PhosphoSitePlus	COSMIC	1.639	Up-regulation
TK_PDGFR_KIT_Y	P10721	KIT	P10721	KIT	Y570	T574I	574	Missense	distal	4	no	3.527	4.163	EPSD;PhosphoSitePlus	COSMIC	1.639	Up-regulation
TK_PDGFR_KIT_Y	P10721	KIT	P10721	KIT	Y570	I563L	563	Missense	distal	-7	no	3.527	3.404	EPSD;PhosphoSitePlus	COSMIC	1.639	Down-regulation
TK_PDGFR_KIT_Y	P10721	KIT	P10721	KIT	Y570	P577H	577	Missense	distal	7	no	3.527	3.469	EPSD;PhosphoSitePlus	COSMIC	1.639	Down-regulation
TK_PDGFR_KIT_Y	P10721	KIT	P10721	KIT	Y570	D572E	572	Missense	proximal	2	no	3.527	3.529	EPSD;PhosphoSitePlus	COSMIC	1.639	Up-regulation
TK_PDGFR_KIT_Y	P10721	KIT	P10721	KIT	Y570	V569G	569	Missense	proximal	-1	no	3.527	3.562	EPSD;PhosphoSitePlus	COSMIC	1.639	Up-regulation
TK_PDGFR_KIT_Y	P10721	KIT	P10721	KIT	Y570	G565V	565	Missense	distal	-5	no	3.527	2.937	EPSD;PhosphoSitePlus	COSMIC	1.639	Down-regulation
TK_PDGFR_KIT_Y	P10721	KIT	P10721	KIT	Y570	V569I	569	Missense	proximal	-1	no	3.527	3.564	EPSD;PhosphoSitePlus	COSMIC	1.639	Up-regulation
TK_PDGFR_KIT_Y	P10721	KIT	P10721	KIT	Y570	N566T	566	Missense	distal	-4	no	3.527	3.489	EPSD;PhosphoSitePlus	COSMIC	1.639	Down-regulation
TK_PDGFR_KIT_Y	P10721	KIT	P10721	KIT	Y570	D572A	572	Missense	proximal	2	no	3.527	3.533	EPSD;PhosphoSitePlus	COSMIC	1.639	Up-regulation
TK_PDGFR_KIT_Y	P10721	KIT	P10721	KIT	Y570	G565E	565	Missense	distal	-5	no	3.527	3.008	EPSD;PhosphoSitePlus	COSMIC	1.639	Down-regulation
TK_PDGFR_KIT_Y	P10721	KIT	P10721	KIT	Y570	V569D	569	Missense	proximal	-1	no	3.527	3.559	EPSD;PhosphoSitePlus	COSMIC	1.639	Up-regulation
TK_PDGFR_KIT_Y	P10721	KIT	P10721	KIT	Y570	I571L	571	Missense	proximal	1	no	3.527	3.628	EPSD;PhosphoSitePlus	COSMIC	1.639	Up-regulation
TK_PDGFR_KIT_Y	P10721	KIT	P10721	KIT	Y578	H580Y	580	Missense	proximal	2	no	1.744	1.720	EPSD	COSMIC	1.639	Down-regulation
TK_PDGFR_KIT_Y	P10721	KIT	P10721	KIT	Y578	L576F	576	Missense	proximal	-2	no	1.744	1.746	EPSD	COSMIC	1.639	Up-regulation
TK_PDGFR_KIT_Y	P10721	KIT	P10721	KIT	Y578	D579N	579	Missense	proximal	1	no	1.744	1.839	EPSD	COSMIC	1.639	Up-regulation
TK_PDGFR_KIT_Y	P10721	KIT	P10721	KIT	Y578	L576R	576	Missense	proximal	-2	no	1.744	1.747	EPSD	COSMIC	1.639	Up-regulation
TK_PDGFR_KIT_Y	P10721	KIT	P10721	KIT	Y578	D572N	572	Missense	distal	-6	no	1.744	1.672	EPSD	COSMIC	1.639	Down-regulation
TK_PDGFR_KIT_Y	P10721	KIT	P10721	KIT	Y578	F584S	584	Missense	distal	6	no	1.744	1.773	EPSD	COSMIC	1.639	Up-regulation
TK_PDGFR_KIT_Y	P10721	KIT	P10721	KIT	Y578	F584L	584	Missense	distal	6	no	1.744	1.749	EPSD	COSMIC	1.639	Up-regulation
TK_PDGFR_KIT_Y	P10721	KIT	P10721	KIT	Y578	P577S	577	Missense	proximal	-1	no	1.744	1.633	EPSD	COSMIC	1.639	Loss
TK_PDGFR_KIT_Y	P10721	KIT	P10721	KIT	Y578	E583G	583	Missense	distal	5	no	1.744	1.758	EPSD	COSMIC	1.639	Up-regulation
TK_PDGFR_KIT_Y	P10721	KIT	P10721	KIT	Y578	P577K	577	Missense	proximal	-1	no	1.744	1.647	EPSD	COSMIC	1.639	Down-regulation
TK_PDGFR_KIT_Y	P10721	KIT	P10721	KIT	Y578	Q575H	575	Missense	distal	-3	no	1.744	1.702	EPSD	COSMIC	1.639	Down-regulation
TK_PDGFR_KIT_Y	P10721	KIT	P10721	KIT	Y578	I571V	571	Missense	distal	-7	no	1.744	1.587	EPSD	COSMIC	1.639	Loss
TK_PDGFR_KIT_Y	P10721	KIT	P10721	KIT	Y578	D572G	572	Missense	distal	-6	no	1.744	1.833	EPSD	COSMIC	1.639	Up-regulation
TK_PDGFR_KIT_Y	P10721	KIT	P10721	KIT	Y578	T574P	574	Missense	distal	-4	no	1.744	1.723	EPSD	COSMIC	1.639	Down-regulation
TK_PDGFR_KIT_Y	P10721	KIT	P10721	KIT	Y578	K581R	581	Missense	distal	3	no	1.744	1.770	EPSD	COSMIC	1.639	Up-regulation
TK_PDGFR_KIT_Y	P10721	KIT	P10721	KIT	Y578	I571R	571	Missense	distal	-7	no	1.744	1.605	EPSD	COSMIC	1.639	Loss
TK_PDGFR_KIT_Y	P10721	KIT	P10721	KIT	Y578	E583V	583	Missense	distal	5	no	1.744	1.763	EPSD	COSMIC	1.639	Up-regulation
TK_PDGFR_KIT_Y	P10721	KIT	P10721	KIT	Y578	P573R	573	Missense	distal	-5	no	1.744	1.498	EPSD	COSMIC	1.639	Loss
TK_PDGFR_KIT_Y	P10721	KIT	P10721	KIT	Y578	D572Y	572	Missense	distal	-6	no	1.744	1.757	EPSD	COSMIC	1.639	Up-regulation
TK_PDGFR_KIT_Y	P10721	KIT	P10721	KIT	Y578	E583K	583	Missense	distal	5	no	1.744	1.747	EPSD	COSMIC	1.639	Up-regulation
TK_PDGFR_KIT_Y	P10721	KIT	P10721	KIT	Y578	I571K	571	Missense	distal	-7	no	1.744	1.653	EPSD	COSMIC	1.639	Down-regulation
TK_PDGFR_KIT_Y	P10721	KIT	P10721	KIT	Y578	I571M	571	Missense	distal	-7	no	1.744	1.612	EPSD	COSMIC	1.639	Loss
TK_PDGFR_KIT_Y	P10721	KIT	P10721	KIT	Y578	D579Y	579	Missense	proximal	1	no	1.744	1.968	EPSD	COSMIC	1.639	Up-regulation
TK_PDGFR_KIT_Y	P10721	KIT	P10721	KIT	Y578	D579E	579	Missense	proximal	1	no	1.744	1.977	EPSD	COSMIC	1.639	Up-regulation
TK_PDGFR_KIT_Y	P10721	KIT	P10721	KIT	Y578	P585T	585	Missense	distal	7	no	1.744	1.731	EPSD	COSMIC	1.639	Down-regulation
TK_PDGFR_KIT_Y	P10721	KIT	P10721	KIT	Y578	P585S	585	Missense	distal	7	no	1.744	1.777	EPSD	COSMIC	1.639	Up-regulation
TK_PDGFR_KIT_Y	P10721	KIT	P10721	KIT	Y578	T574I	574	Missense	distal	-4	no	1.744	1.652	EPSD	COSMIC	1.639	Down-regulation
TK_PDGFR_KIT_Y	P10721	KIT	P10721	KIT	Y578	P577H	577	Missense	proximal	-1	no	1.744	1.788	EPSD	COSMIC	1.639	Up-regulation
TK_PDGFR_KIT_Y	P10721	KIT	P10721	KIT	Y578	D572E	572	Missense	distal	-6	no	1.744	1.766	EPSD	COSMIC	1.639	Up-regulation
TK_PDGFR_KIT_Y	P10721	KIT	P10721	KIT	Y578	D572A	572	Missense	distal	-6	no	1.744	1.689	EPSD	COSMIC	1.639	Down-regulation
TK_PDGFR_KIT_Y	P10721	KIT	P10721	KIT	Y578	Y578N	578	Missense	central	0	yes	1.744	0.000	EPSD	COSMIC	1.639	Loss
TK_PDGFR_KIT_Y	P10721	KIT	P10721	KIT	Y578	K581Q	581	Missense	distal	3	no	1.744	1.779	EPSD	COSMIC	1.639	Up-regulation
TK_PDGFR_KIT_Y	P10721	KIT	P10721	KIT	Y578	I571L	571	Missense	distal	-7	no	1.744	1.620	EPSD	COSMIC	1.639	Loss
TK_PDGFR_KIT_Y	P10721	KIT	P10721	KIT	Y703	K710E	710	Missense	distal	7	no	3.477	3.461	EPSD;PhosphoSitePlus	COSMIC	1.639	Down-regulation
TK_PDGFR_KIT_Y	P10721	KIT	P10721	KIT	Y703	A700V	700	Missense	distal	-3	no	3.477	3.440	EPSD;PhosphoSitePlus	COSMIC	1.639	Down-regulation
TK_PDGFR_KIT_Y	P10721	KIT	P10721	KIT	Y703	H697Y	697	Missense	distal	-6	no	3.477	3.401	EPSD;PhosphoSitePlus	COSMIC;CCLE	1.639	Down-regulation
TK_PDGFR_KIT_Y	P10721	KIT	P10721	KIT	Y703	A698E	698	Missense	distal	-5	no	3.477	3.206	EPSD;PhosphoSitePlus	COSMIC	1.639	Down-regulation
TK_PDGFR_KIT_Y	P10721	KIT	P10721	KIT	Y703	Y703H	703	Missense	central	0	yes	3.477	0.000	EPSD;PhosphoSitePlus	COSMIC	1.639	Loss
TK_PDGFR_KIT_Y	P10721	KIT	P10721	KIT	Y703	L702V	702	Missense	proximal	-1	no	3.477	3.552	EPSD;PhosphoSitePlus	COSMIC	1.639	Up-regulation
TK_PDGFR_KIT_Y	P10721	KIT	P10721	KIT	Y703	A701E	701	Missense	proximal	-2	no	3.477	3.476	EPSD;PhosphoSitePlus	COSMIC	1.639	Down-regulation
TK_PDGFR_KIT_Y	P10721	KIT	P10721	KIT	Y703	S709F	709	Missense	distal	6	no	3.477	3.448	EPSD;PhosphoSitePlus	COSMIC	1.639	Down-regulation
TK_PDGFR_KIT_Y	P10721	KIT	P10721	KIT	Y703	K704N	704	Missense	proximal	1	no	3.477	3.271	EPSD;PhosphoSitePlus	COSMIC	1.639	Down-regulation
TK_PDGFR_KIT_Y	P10721	KIT	P10721	KIT	Y703	A700S	700	Missense	distal	-3	no	3.477	3.527	EPSD;PhosphoSitePlus	COSMIC	1.639	Up-regulation
TK_PDGFR_KIT_Y	P10721	KIT	P10721	KIT	Y703	K704T	704	Missense	proximal	1	no	3.477	3.485	EPSD;PhosphoSitePlus	COSMIC	1.639	Up-regulation
TK_PDGFR_KIT_Y	P10721	KIT	P10721	KIT	Y703	D696G	696	Missense	distal	-7	no	3.477	3.578	EPSD;PhosphoSitePlus	COSMIC	1.639	Up-regulation
TK_PDGFR_KIT_Y	P10721	KIT	P10721	KIT	Y721	D723K	723	Missense	proximal	2	no	3.319	3.339	EPSD;PhosphoSitePlus	COSMIC	1.639	Up-regulation
TK_PDGFR_KIT_Y	P10721	KIT	P10721	KIT	Y721	P726L	726	Missense	distal	5	no	3.319	3.340	EPSD;PhosphoSitePlus	COSMIC	1.639	Up-regulation
TK_PDGFR_KIT_Y	P10721	KIT	P10721	KIT	Y721	T718S	718	Missense	distal	-3	no	3.319	3.356	EPSD;PhosphoSitePlus	COSMIC	1.639	Up-regulation
TK_PDGFR_KIT_Y	P10721	KIT	P10721	KIT	Y721	C714S	714	Missense	distal	-7	no	3.319	3.275	EPSD;PhosphoSitePlus	COSMIC	1.639	Down-regulation
TK_PDGFR_KIT_Y	P10721	KIT	P10721	KIT	Y721	N719K	719	Missense	proximal	-2	no	3.319	3.316	EPSD;PhosphoSitePlus	COSMIC	1.639	Down-regulation
TK_PDGFR_KIT_Y	P10721	KIT	P10721	KIT	Y721	D723A	723	Missense	proximal	2	no	3.319	3.325	EPSD;PhosphoSitePlus	COSMIC	1.639	Up-regulation
TK_PDGFR_KIT_Y	P10721	KIT	P10721	KIT	Y721	M724I	724	Missense	distal	3	no	3.319	3.346	EPSD;PhosphoSitePlus	COSMIC	1.639	Up-regulation
TK_PDGFR_KIT_Y	P10721	KIT	P10721	KIT	Y721	E720K	720	Missense	proximal	-1	no	3.319	3.275	EPSD;PhosphoSitePlus	COSMIC	1.639	Down-regulation
TK_PDGFR_KIT_Y	P10721	KIT	P10721	KIT	Y721	D716H	716	Missense	distal	-5	no	3.319	2.988	EPSD;PhosphoSitePlus	COSMIC	1.639	Down-regulation
TK_PDGFR_KIT_Y	P10721	KIT	P10721	KIT	Y823	D816X	816	Missense	distal	-7	no	4.730	4.693	EPSD;PhosphoSitePlus	COSMIC	1.639	Down-regulation
TK_PDGFR_KIT_Y	P10721	KIT	P10721	KIT	Y823	Y823D	823	Missense	central	0	yes	4.730	0.000	EPSD;PhosphoSitePlus	COSMIC	1.639	Loss
TK_PDGFR_KIT_Y	P10721	KIT	P10721	KIT	Y823	N822S	822	Missense	proximal	-1	no	4.730	4.625	EPSD;PhosphoSitePlus	COSMIC	1.639	Down-regulation
TK_PDGFR_KIT_Y	P10721	KIT	P10721	KIT	Y823	D816G	816	Missense	distal	-7	no	4.730	4.832	EPSD;PhosphoSitePlus	COSMIC	1.639	Up-regulation
TK_PDGFR_KIT_Y	P10721	KIT	P10721	KIT	Y823	D816F	816	Missense	distal	-7	no	4.730	4.692	EPSD;PhosphoSitePlus	COSMIC	1.639	Down-regulation
TK_PDGFR_KIT_Y	P10721	KIT	P10721	KIT	Y823	D820G	820	Missense	distal	-3	no	4.730	4.691	EPSD;PhosphoSitePlus	COSMIC	1.639	Down-regulation
TK_PDGFR_KIT_Y	P10721	KIT	P10721	KIT	Y823	D816N	816	Missense	distal	-7	no	4.730	4.636	EPSD;PhosphoSitePlus	COSMIC	1.639	Down-regulation
TK_PDGFR_KIT_Y	P10721	KIT	P10721	KIT	Y823	D816A	816	Missense	distal	-7	no	4.730	4.721	EPSD;PhosphoSitePlus	COSMIC	1.639	Down-regulation
TK_PDGFR_KIT_Y	P10721	KIT	P10721	KIT	Y823	D820E	820	Missense	distal	-3	no	4.730	4.770	EPSD;PhosphoSitePlus	COSMIC	1.639	Up-regulation
TK_PDGFR_KIT_Y	P10721	KIT	P10721	KIT	Y823	D816E	816	Missense	distal	-7	no	4.730	4.658	EPSD;PhosphoSitePlus	COSMIC	1.639	Down-regulation
TK_PDGFR_KIT_Y	P10721	KIT	P10721	KIT	Y823	N822H	822	Missense	proximal	-1	no	4.730	4.780	EPSD;PhosphoSitePlus	COSMIC	1.639	Up-regulation
TK_PDGFR_KIT_Y	P10721	KIT	P10721	KIT	Y823	D820V	820	Missense	distal	-3	no	4.730	4.686	EPSD;PhosphoSitePlus	COSMIC	1.639	Down-regulation
TK_PDGFR_KIT_Y	P10721	KIT	P10721	KIT	Y823	D820H	820	Missense	distal	-3	no	4.730	4.695	EPSD;PhosphoSitePlus	COSMIC	1.639	Down-regulation
TK_PDGFR_KIT_Y	P10721	KIT	P10721	KIT	Y823	N822T	822	Missense	proximal	-1	no	4.730	4.653	EPSD;PhosphoSitePlus	COSMIC	1.639	Down-regulation
TK_PDGFR_KIT_Y	P10721	KIT	P10721	KIT	Y823	Y823C	823	Missense	central	0	yes	4.730	0.000	EPSD;PhosphoSitePlus	COSMIC	1.639	Loss
TK_PDGFR_KIT_Y	P10721	KIT	P10721	KIT	Y823	D820N	820	Missense	distal	-3	no	4.730	4.758	EPSD;PhosphoSitePlus	COSMIC	1.639	Up-regulation
TK_PDGFR_KIT_Y	P10721	KIT	P10721	KIT	Y823	V825A	825	Missense	proximal	2	no	4.730	4.713	EPSD;PhosphoSitePlus	COSMIC	1.639	Down-regulation
TK_PDGFR_KIT_Y	P10721	KIT	P10721	KIT	Y823	K826T	826	Missense	distal	3	no	4.730	4.759	EPSD;PhosphoSitePlus	COSMIC	1.639	Up-regulation
TK_PDGFR_KIT_Y	P10721	KIT	P10721	KIT	Y823	D820A	820	Missense	distal	-3	no	4.730	4.723	EPSD;PhosphoSitePlus	COSMIC	1.639	Down-regulation
TK_PDGFR_KIT_Y	P10721	KIT	P10721	KIT	Y823	D816I	816	Missense	distal	-7	no	4.730	4.818	EPSD;PhosphoSitePlus	COSMIC	1.639	Up-regulation
TK_PDGFR_KIT_Y	P10721	KIT	P10721	KIT	Y823	I817T	817	Missense	distal	-6	no	4.730	4.322	EPSD;PhosphoSitePlus	COSMIC	1.639	Down-regulation
TK_PDGFR_KIT_Y	P10721	KIT	P10721	KIT	Y823	N819S	819	Missense	distal	-4	no	4.730	4.783	EPSD;PhosphoSitePlus	COSMIC	1.639	Up-regulation
TK_PDGFR_KIT_Y	P10721	KIT	P10721	KIT	Y823	I817V	817	Missense	distal	-6	no	4.730	4.492	EPSD;PhosphoSitePlus	COSMIC	1.639	Down-regulation
TK_PDGFR_KIT_Y	P10721	KIT	P10721	KIT	Y823	I817L	817	Missense	distal	-6	no	4.730	4.530	EPSD;PhosphoSitePlus	COSMIC	1.639	Down-regulation
TK_PDGFR_KIT_Y	P10721	KIT	P10721	KIT	Y823	Y823N	823	Missense	central	0	yes	4.730	0.000	EPSD;PhosphoSitePlus	COSMIC	1.639	Loss
TK_PDGFR_KIT_Y	P10721	KIT	P10721	KIT	Y823	R830L	830	Missense	distal	7	no	4.730	4.722	EPSD;PhosphoSitePlus	COSMIC	1.639	Down-regulation
TK_PDGFR_KIT_Y	P10721	KIT	P10721	KIT	Y823	N819Y	819	Missense	distal	-4	no	4.730	4.629	EPSD;PhosphoSitePlus	COSMIC	1.639	Down-regulation
TK_PDGFR_KIT_Y	P10721	KIT	P10721	KIT	Y823	I817F	817	Missense	distal	-6	no	4.730	4.461	EPSD;PhosphoSitePlus	COSMIC	1.639	Down-regulation
TK_PDGFR_KIT_Y	P10721	KIT	P10721	KIT	Y823	V825I	825	Missense	proximal	2	no	4.730	4.726	EPSD;PhosphoSitePlus	COSMIC	1.639	Down-regulation
TK_PDGFR_KIT_Y	P10721	KIT	P10721	KIT	Y823	A829V	829	Missense	distal	6	no	4.730	4.783	EPSD;PhosphoSitePlus	COSMIC	1.639	Up-regulation
TK_PDGFR_KIT_Y	P10721	KIT	P10721	KIT	Y823	V824L	824	Missense	proximal	1	no	4.730	4.715	EPSD;PhosphoSitePlus	COSMIC	1.639	Down-regulation
TK_PDGFR_KIT_Y	P10721	KIT	P10721	KIT	Y823	S821F	821	Missense	proximal	-2	no	4.730	4.724	EPSD;PhosphoSitePlus	COSMIC	1.639	Down-regulation
TK_PDGFR_KIT_Y	P10721	KIT	P10721	KIT	Y823	Y823H	823	Missense	central	0	yes	4.730	0.000	EPSD;PhosphoSitePlus	COSMIC	1.639	Loss
TK_PDGFR_KIT_Y	P10721	KIT	P10721	KIT	Y823	G827R	827	Missense	distal	4	no	4.730	4.517	EPSD;PhosphoSitePlus	COSMIC	1.639	Down-regulation
TK_PDGFR_KIT_Y	P10721	KIT	P10721	KIT	Y823	N822D	822	Missense	proximal	-1	no	4.730	4.746	EPSD;PhosphoSitePlus	COSMIC	1.639	Up-regulation
TK_PDGFR_KIT_Y	P10721	KIT	P10721	KIT	Y936	E930D	930	Missense	distal	-6	no	3.746	3.723	EPSD;PhosphoSitePlus	COSMIC	1.639	Down-regulation
TK_PDGFR_KIT_Y	P10721	KIT	P10721	KIT	Y936	I935V	935	Missense	proximal	-1	no	3.746	3.708	EPSD;PhosphoSitePlus	COSMIC	1.639	Down-regulation
TK_PDGFR_KIT_Y	P10721	KIT	P10721	KIT	Y936	S931I	931	Missense	distal	-5	no	3.746	4.207	EPSD;PhosphoSitePlus	COSMIC	1.639	Up-regulation
TK_PDGFR_KIT_Y	P10721	KIT	P10721	KIT	Y936	L939V	939	Missense	distal	3	no	3.746	3.742	EPSD;PhosphoSitePlus	COSMIC	1.639	Down-regulation
TK_PDGFR_KIT_Y	Q9GZY6	LAT2	P10721	KIT	Y110	G105E	105	Missense	distal	-5	no	4.234	3.715	PhosphoSitePlus;EPSD	COSMIC	1.639	Down-regulation
Other_PEK_PKR_EIF2AK2_ST	P19525	EIF2AK2	P19525	EIF2AK2	S242	S242F	242	Missense	central	0	yes	110.237	0.000	PhosphoSitePlus;EPSD	COSMIC	66.906	Loss
Other_PEK_PKR_EIF2AK2_ST	P19525	EIF2AK2	P19525	EIF2AK2	S242	P245S	245	Missense	distal	3	no	110.237	112.552	PhosphoSitePlus;EPSD	COSMIC	66.906	Up-regulation
Other_PEK_PKR_EIF2AK2_ST	P19525	EIF2AK2	P19525	EIF2AK2	T255	T255A	255	Missense	central	0	yes	117.648	0.000	EPSD;PhosphoSitePlus	COSMIC	66.906	Loss
Other_PEK_PKR_EIF2AK2_ST	P19525	EIF2AK2	P19525	EIF2AK2	T255	V259A	259	Missense	distal	4	no	117.648	119.054	EPSD;PhosphoSitePlus	COSMIC;GDSC;CCLE	66.906	Up-regulation
Other_PEK_PKR_EIF2AK2_ST	P19525	EIF2AK2	P19525	EIF2AK2	T255	R262W	262	Missense	distal	7	no	117.648	114.602	EPSD;PhosphoSitePlus	COSMIC	66.906	Down-regulation
Other_PEK_PKR_EIF2AK2_ST	P19525	EIF2AK2	P19525	EIF2AK2	T258	T255A	255	Missense	distal	-3	no	106.644	109.242	EPSD;PhosphoSitePlus	COSMIC	66.906	Up-regulation
Other_PEK_PKR_EIF2AK2_ST	P19525	EIF2AK2	P19525	EIF2AK2	T258	V259A	259	Missense	proximal	1	no	106.644	108.445	EPSD;PhosphoSitePlus	COSMIC;GDSC;CCLE	66.906	Up-regulation
Other_PEK_PKR_EIF2AK2_ST	P19525	EIF2AK2	P19525	EIF2AK2	T258	R262W	262	Missense	distal	4	no	106.644	107.420	EPSD;PhosphoSitePlus	COSMIC	66.906	Up-regulation
Other_PEK_PKR_EIF2AK2_ST	P19525	EIF2AK2	P19525	EIF2AK2	T446	R445Q	445	Missense	proximal	-1	no	93.940	94.596	EPSD;PhosphoSitePlus	COSMIC	66.906	Up-regulation
Other_PEK_PKR_EIF2AK2_ST	P19525	EIF2AK2	P19525	EIF2AK2	T446	L439V	439	Missense	distal	-7	no	93.940	93.635	EPSD;PhosphoSitePlus	COSMIC;GDSC;CCLE	66.906	Down-regulation
Other_PEK_PKR_EIF2AK2_ST	P19525	EIF2AK2	P19525	EIF2AK2	T446	S448N	448	Missense	proximal	2	no	93.940	93.720	EPSD;PhosphoSitePlus	COSMIC	66.906	Down-regulation
Other_PEK_PKR_EIF2AK2_ST	P19525	EIF2AK2	P19525	EIF2AK2	T446	K444R	444	Missense	proximal	-2	no	93.940	92.478	EPSD;PhosphoSitePlus	COSMIC	66.906	Down-regulation
Other_PEK_PKR_EIF2AK2_ST	P19525	EIF2AK2	P19525	EIF2AK2	T451	R445Q	445	Missense	distal	-6	no	104.200	97.170	EPSD;PhosphoSitePlus	COSMIC	66.906	Down-regulation
Other_PEK_PKR_EIF2AK2_ST	P19525	EIF2AK2	P19525	EIF2AK2	T451	S448N	448	Missense	distal	-3	no	104.200	103.558	EPSD;PhosphoSitePlus	COSMIC	66.906	Down-regulation
Other_PEK_PKR_EIF2AK2_ST	P19525	EIF2AK2	P19525	EIF2AK2	T451	K444R	444	Missense	distal	-7	no	104.200	103.483	EPSD;PhosphoSitePlus	COSMIC	66.906	Down-regulation
Other_PEK_PKR_EIF2AK2_ST	P05198	EIF2S1	P19525	EIF2AK2	S49	L48V	48	Missense	proximal	-1	no	99.991	99.664	PhosphoSitePlus;EPSD	COSMIC	66.906	Down-regulation
Other_PEK_PKR_EIF2AK2_ST	P05198	EIF2S1	P19525	EIF2AK2	S49	R55H	55	Missense	distal	6	no	99.991	102.004	PhosphoSitePlus;EPSD	COSMIC	66.906	Up-regulation
Other_PEK_PKR_EIF2AK2_ST	P05198	EIF2S1	P19525	EIF2AK2	S49	R55C	55	Missense	distal	6	no	99.991	93.275	PhosphoSitePlus;EPSD	COSMIC	66.906	Down-regulation
Other_PEK_PKR_EIF2AK2_ST	P05198	EIF2S1	P19525	EIF2AK2	S52	L48V	48	Missense	distal	-4	no	109.481	109.190	EPSD;PhosphoSitePlus	COSMIC	66.906	Down-regulation
Other_PEK_PKR_EIF2AK2_ST	P05198	EIF2S1	P19525	EIF2AK2	S52	R55H	55	Missense	distal	3	no	109.481	108.719	EPSD;PhosphoSitePlus	COSMIC	66.906	Down-regulation
Other_PEK_PKR_EIF2AK2_ST	P05198	EIF2S1	P19525	EIF2AK2	S52	R55C	55	Missense	distal	3	no	109.481	108.782	EPSD;PhosphoSitePlus	COSMIC	66.906	Down-regulation
Other_PEK_PKR_EIF2AK2_ST	P10636	MAPT	P19525	EIF2AK2	T111	I108V	108	Missense	distal	-3	no	71.982	74.782	EPSD	COSMIC	66.906	Up-regulation
Other_PEK_PKR_EIF2AK2_ST	P10636	MAPT	P19525	EIF2AK2	T111	G107R	107	Missense	distal	-4	no	71.982	75.750	EPSD	COSMIC	66.906	Up-regulation
Other_PEK_PKR_EIF2AK2_ST	P10636	MAPT	P19525	EIF2AK2	T123	V122M	122	Missense	proximal	-1	no	83.137	83.917	EPSD	COSMIC	66.906	Up-regulation
Other_PEK_PKR_EIF2AK2_ST	P10636	MAPT	P19525	EIF2AK2	T466	T466M	466	Missense	central	0	yes	68.310	0.000	EPSD	COSMIC;GDSC;CCLE	66.906	Loss
Other_PEK_PKR_EIF2AK2_ST	P10636	MAPT	P19525	EIF2AK2	T466	K467T	467	Missense	proximal	1	no	68.310	66.079	EPSD	COSMIC	66.906	Loss
Other_PEK_PKR_EIF2AK2_ST	P10636	MAPT	P19525	EIF2AK2	S575	T580N	580	Missense	distal	5	no	73.751	72.513	EPSD	COSMIC	66.906	Down-regulation
Other_PEK_PKR_EIF2AK2_ST	P10636	MAPT	P19525	EIF2AK2	S575	G578S	578	Missense	distal	3	no	73.751	75.673	EPSD	COSMIC	66.906	Up-regulation
Other_PEK_PKR_EIF2AK2_ST	P10636	MAPT	P19525	EIF2AK2	S575	K571E	571	Missense	distal	-4	no	73.751	73.304	EPSD	COSMIC	66.906	Down-regulation
Other_PEK_PKR_EIF2AK2_ST	P10636	MAPT	P19525	EIF2AK2	S575	P568S	568	Missense	distal	-7	no	73.751	73.392	EPSD	COSMIC	66.906	Down-regulation
Other_PEK_PKR_EIF2AK2_ST	P10636	MAPT	P19525	EIF2AK2	S579	T580N	580	Missense	proximal	1	no	104.255	106.054	EPSD	COSMIC	66.906	Up-regulation
Other_PEK_PKR_EIF2AK2_ST	P10636	MAPT	P19525	EIF2AK2	S579	G578S	578	Missense	proximal	-1	no	104.255	102.348	EPSD	COSMIC	66.906	Down-regulation
Other_PEK_PKR_EIF2AK2_ST	P10636	MAPT	P19525	EIF2AK2	T580	T580N	580	Missense	central	0	yes	92.966	0.000	EPSD	COSMIC	66.906	Loss
Other_PEK_PKR_EIF2AK2_ST	P10636	MAPT	P19525	EIF2AK2	T580	G578S	578	Missense	proximal	-2	no	92.966	95.662	EPSD	COSMIC	66.906	Up-regulation
Other_PEK_PKR_EIF2AK2_ST	P10636	MAPT	P19525	EIF2AK2	S606	N613D	613	Missense	distal	7	no	70.799	75.017	EPSD	COSMIC	66.906	Up-regulation
Other_PEK_PKR_EIF2AK2_ST	P10636	MAPT	P19525	EIF2AK2	S606	S602G	602	Missense	distal	-4	no	70.799	67.837	EPSD	COSMIC	66.906	Down-regulation
Other_PEK_PKR_EIF2AK2_ST	P10636	MAPT	P19525	EIF2AK2	S606	C608W	608	Missense	proximal	2	no	70.799	70.638	EPSD	COSMIC	66.906	Down-regulation
Other_PEK_PKR_EIF2AK2_ST	P10636	MAPT	P19525	EIF2AK2	S606	S610L	610	Missense	distal	4	no	70.799	70.163	EPSD	COSMIC	66.906	Down-regulation
Other_PEK_PKR_EIF2AK2_ST	P10636	MAPT	P19525	EIF2AK2	S606	D600E	600	Missense	distal	-6	no	70.799	88.105	EPSD	COSMIC	66.906	Up-regulation
Other_PEK_PKR_EIF2AK2_ST	P10636	MAPT	P19525	EIF2AK2	S610	N613D	613	Missense	distal	3	no	75.712	66.523	EPSD	COSMIC	66.906	Loss
Other_PEK_PKR_EIF2AK2_ST	P10636	MAPT	P19525	EIF2AK2	S610	C608W	608	Missense	proximal	-2	no	75.712	73.770	EPSD	COSMIC	66.906	Down-regulation
Other_PEK_PKR_EIF2AK2_ST	P10636	MAPT	P19525	EIF2AK2	S610	S610L	610	Missense	central	0	yes	75.712	0.000	EPSD	COSMIC	66.906	Loss
Other_PEK_PKR_EIF2AK2_ST	P10636	MAPT	P19525	EIF2AK2	S637	S633N	633	Missense	distal	-4	no	71.789	73.474	EPSD	COSMIC	66.906	Up-regulation
Other_PEK_PKR_EIF2AK2_ST	P10636	MAPT	P19525	EIF2AK2	S637	S633I	633	Missense	distal	-4	no	71.789	73.214	EPSD	COSMIC	66.906	Up-regulation
Other_PEK_PKR_EIF2AK2_ST	P10636	MAPT	P19525	EIF2AK2	S673	V680I	680	Missense	distal	7	no	99.190	103.478	EPSD	COSMIC	66.906	Up-regulation
Other_PEK_PKR_EIF2AK2_ST	P10636	MAPT	P19525	EIF2AK2	S673	S669L	669	Missense	distal	-4	no	99.190	100.857	EPSD	COSMIC	66.906	Up-regulation
Other_PEK_PKR_EIF2AK2_ST	P10636	MAPT	P19525	EIF2AK2	S673	R666K	666	Missense	distal	-7	no	99.190	99.908	EPSD	COSMIC	66.906	Up-regulation
Other_PEK_PKR_EIF2AK2_ST	P10636	MAPT	P19525	EIF2AK2	S673	S673F	673	Missense	central	0	yes	99.190	0.000	EPSD	COSMIC	66.906	Loss
Other_PEK_PKR_EIF2AK2_ST	P10636	MAPT	P19525	EIF2AK2	S673	K670N	670	Missense	distal	-3	no	99.190	97.968	EPSD	COSMIC	66.906	Down-regulation
Other_PEK_PKR_EIF2AK2_ST	P10636	MAPT	P19525	EIF2AK2	S673	L674Q	674	Missense	proximal	1	no	99.190	98.474	EPSD	COSMIC	66.906	Down-regulation
Other_PEK_PKR_EIF2AK2_ST	P06493	CDK1	P19525	EIF2AK2	S46	S53C	53	Missense	distal	7	no	97.058	97.223	EPSD	COSMIC	66.906	Up-regulation
Other_PEK_PKR_EIF2AK2_ST	P04637	TP53	P19525	EIF2AK2	S46	D49N	49	Missense	distal	3	no	58.440	67.629	EPSD	COSMIC	66.906	Gain
Other_PEK_PKR_EIF2AK2_ST	P04637	TP53	P19525	EIF2AK2	S99	S94P	94	Missense	distal	-5	no	65.275	67.123	EPSD	COSMIC	66.906	Gain
Other_PEK_PKR_EIF2AK2_ST	P04637	TP53	P19525	EIF2AK2	S99	S106I	106	Missense	distal	7	no	65.275	67.964	EPSD	COSMIC	66.906	Gain
Other_PEK_PKR_EIF2AK2_ST	P04637	TP53	P19525	EIF2AK2	S99	L93M	93	Missense	distal	-6	no	65.275	80.348	EPSD	COSMIC	66.906	Gain
Other_PEK_PKR_EIF2AK2_ST	P04637	TP53	P19525	EIF2AK2	S149	P142T	142	Missense	distal	-7	no	69.762	69.640	EPSD	COSMIC	66.906	Down-regulation
Other_PEK_PKR_EIF2AK2_ST	P04637	TP53	P19525	EIF2AK2	S149	P142S	142	Missense	distal	-7	no	69.762	69.403	EPSD	COSMIC	66.906	Down-regulation
Other_PEK_PKR_EIF2AK2_ST	P04637	TP53	P19525	EIF2AK2	S149	P151N	151	Missense	proximal	2	no	69.762	69.407	EPSD	COSMIC	66.906	Down-regulation
Other_PEK_PKR_EIF2AK2_ST	P04637	TP53	P19525	EIF2AK2	S149	P152A	152	Missense	distal	3	no	69.762	71.632	EPSD	COSMIC	66.906	Up-regulation
Other_PEK_PKR_EIF2AK2_ST	P04637	TP53	P19525	EIF2AK2	S149	P152T	152	Missense	distal	3	no	69.762	70.465	EPSD	COSMIC	66.906	Up-regulation
Other_PEK_PKR_EIF2AK2_ST	P04637	TP53	P19525	EIF2AK2	S149	P152H	152	Missense	distal	3	no	69.762	67.657	EPSD	COSMIC	66.906	Down-regulation
Other_PEK_PKR_EIF2AK2_ST	P04637	TP53	P19525	EIF2AK2	S149	P142A	142	Missense	distal	-7	no	69.762	69.564	EPSD	COSMIC	66.906	Down-regulation
Other_PEK_PKR_EIF2AK2_ST	P04637	TP53	P19525	EIF2AK2	S149	P142F	142	Missense	distal	-7	no	69.762	69.347	EPSD	COSMIC	66.906	Down-regulation
Other_PEK_PKR_EIF2AK2_ST	P04637	TP53	P19525	EIF2AK2	S149	P153T	153	Missense	distal	4	no	69.762	69.560	EPSD	COSMIC	66.906	Down-regulation
Other_PEK_PKR_EIF2AK2_ST	P04637	TP53	P19525	EIF2AK2	S149	V147I	147	Missense	proximal	-2	no	69.762	70.754	EPSD	COSMIC	66.906	Up-regulation
Other_PEK_PKR_EIF2AK2_ST	P04637	TP53	P19525	EIF2AK2	S149	P153L	153	Missense	distal	4	no	69.762	68.612	EPSD	COSMIC	66.906	Down-regulation
Other_PEK_PKR_EIF2AK2_ST	P04637	TP53	P19525	EIF2AK2	S149	V147D	147	Missense	proximal	-2	no	69.762	69.439	EPSD	COSMIC;GDSC;CCLE	66.906	Down-regulation
Other_PEK_PKR_EIF2AK2_ST	P04637	TP53	P19525	EIF2AK2	S149	S149P	149	Missense	central	0	yes	69.762	0.000	EPSD	COSMIC	66.906	Loss
Other_PEK_PKR_EIF2AK2_ST	P04637	TP53	P19525	EIF2AK2	S149	P152K	152	Missense	distal	3	no	69.762	69.734	EPSD	COSMIC	66.906	Down-regulation
Other_PEK_PKR_EIF2AK2_ST	P04637	TP53	P19525	EIF2AK2	S149	P153S	153	Missense	distal	4	no	69.762	69.248	EPSD	COSMIC	66.906	Down-regulation
Other_PEK_PKR_EIF2AK2_ST	P04637	TP53	P19525	EIF2AK2	S149	G154C	154	Missense	distal	5	no	69.762	68.423	EPSD	COSMIC	66.906	Down-regulation
Other_PEK_PKR_EIF2AK2_ST	P04637	TP53	P19525	EIF2AK2	S149	S149F	149	Missense	central	0	yes	69.762	0.000	EPSD	COSMIC	66.906	Loss
Other_PEK_PKR_EIF2AK2_ST	P04637	TP53	P19525	EIF2AK2	S149	G154D	154	Missense	distal	5	no	69.762	69.478	EPSD	COSMIC	66.906	Down-regulation
Other_PEK_PKR_EIF2AK2_ST	P04637	TP53	P19525	EIF2AK2	S149	W146R	146	Missense	distal	-3	no	69.762	68.669	EPSD	COSMIC	66.906	Down-regulation
Other_PEK_PKR_EIF2AK2_ST	P04637	TP53	P19525	EIF2AK2	S149	Q144R	144	Missense	distal	-5	no	69.762	68.792	EPSD	COSMIC	66.906	Down-regulation
Other_PEK_PKR_EIF2AK2_ST	P04637	TP53	P19525	EIF2AK2	S149	D148V	148	Missense	proximal	-1	no	69.762	69.214	EPSD	COSMIC	66.906	Down-regulation
Other_PEK_PKR_EIF2AK2_ST	P04637	TP53	P19525	EIF2AK2	S149	S149Y	149	Missense	central	0	yes	69.762	0.000	EPSD	COSMIC	66.906	Loss
Other_PEK_PKR_EIF2AK2_ST	P04637	TP53	P19525	EIF2AK2	S149	T150I	150	Missense	proximal	1	no	69.762	70.399	EPSD	COSMIC	66.906	Up-regulation
Other_PEK_PKR_EIF2AK2_ST	P04637	TP53	P19525	EIF2AK2	S149	W146G	146	Missense	distal	-3	no	69.762	70.782	EPSD	COSMIC	66.906	Up-regulation
Other_PEK_PKR_EIF2AK2_ST	P04637	TP53	P19525	EIF2AK2	S149	L145M	145	Missense	distal	-4	no	69.762	69.007	EPSD	COSMIC	66.906	Down-regulation
Other_PEK_PKR_EIF2AK2_ST	P04637	TP53	P19525	EIF2AK2	S149	V143L	143	Missense	distal	-6	no	69.762	54.969	EPSD	COSMIC	66.906	Loss
Other_PEK_PKR_EIF2AK2_ST	P04637	TP53	P19525	EIF2AK2	S149	R156S	156	Missense	distal	7	no	69.762	67.318	EPSD	COSMIC	66.906	Down-regulation
Other_PEK_PKR_EIF2AK2_ST	P04637	TP53	P19525	EIF2AK2	S149	D148E	148	Missense	proximal	-1	no	69.762	69.680	EPSD	COSMIC	66.906	Down-regulation
Other_PEK_PKR_EIF2AK2_ST	P04637	TP53	P19525	EIF2AK2	S149	V147F	147	Missense	proximal	-2	no	69.762	68.039	EPSD	COSMIC	66.906	Down-regulation
Other_PEK_PKR_EIF2AK2_ST	P04637	TP53	P19525	EIF2AK2	S149	T155A	155	Missense	distal	6	no	69.762	64.312	EPSD	COSMIC	66.906	Loss
Other_PEK_PKR_EIF2AK2_ST	P04637	TP53	P19525	EIF2AK2	S149	V147E	147	Missense	proximal	-2	no	69.762	70.714	EPSD	COSMIC	66.906	Up-regulation
Other_PEK_PKR_EIF2AK2_ST	P04637	TP53	P19525	EIF2AK2	S149	G154I	154	Missense	distal	5	no	69.762	69.090	EPSD	COSMIC	66.906	Down-regulation
Other_PEK_PKR_EIF2AK2_ST	P04637	TP53	P19525	EIF2AK2	S149	D148G	148	Missense	proximal	-1	no	69.762	71.815	EPSD	COSMIC	66.906	Up-regulation
Other_PEK_PKR_EIF2AK2_ST	P04637	TP53	P19525	EIF2AK2	S149	Q144K	144	Missense	distal	-5	no	69.762	67.029	EPSD	COSMIC	66.906	Down-regulation
Other_PEK_PKR_EIF2AK2_ST	P04637	TP53	P19525	EIF2AK2	S149	V147A	147	Missense	proximal	-2	no	69.762	71.278	EPSD	COSMIC	66.906	Up-regulation
Other_PEK_PKR_EIF2AK2_ST	P04637	TP53	P19525	EIF2AK2	S149	L145V	145	Missense	distal	-4	no	69.762	69.470	EPSD	COSMIC	66.906	Down-regulation
Other_PEK_PKR_EIF2AK2_ST	P04637	TP53	P19525	EIF2AK2	S149	T150K	150	Missense	proximal	1	no	69.762	71.993	EPSD	COSMIC	66.906	Up-regulation
Other_PEK_PKR_EIF2AK2_ST	P04637	TP53	P19525	EIF2AK2	S149	P153H	153	Missense	distal	4	no	69.762	67.845	EPSD	COSMIC	66.906	Down-regulation
Other_PEK_PKR_EIF2AK2_ST	P04637	TP53	P19525	EIF2AK2	S149	P142Q	142	Missense	distal	-7	no	69.762	69.608	EPSD	COSMIC	66.906	Down-regulation
Other_PEK_PKR_EIF2AK2_ST	P04637	TP53	P19525	EIF2AK2	S149	T155S	155	Missense	distal	6	no	69.762	69.877	EPSD	COSMIC;CCLE	66.906	Up-regulation
Other_PEK_PKR_EIF2AK2_ST	P04637	TP53	P19525	EIF2AK2	S149	D148H	148	Missense	proximal	-1	no	69.762	70.851	EPSD	COSMIC	66.906	Up-regulation
Other_PEK_PKR_EIF2AK2_ST	P04637	TP53	P19525	EIF2AK2	S149	P153A	153	Missense	distal	4	no	69.762	71.425	EPSD	COSMIC	66.906	Up-regulation
Other_PEK_PKR_EIF2AK2_ST	P04637	TP53	P19525	EIF2AK2	S149	T150R	150	Missense	proximal	1	no	69.762	69.650	EPSD	COSMIC	66.906	Down-regulation
Other_PEK_PKR_EIF2AK2_ST	P04637	TP53	P19525	EIF2AK2	S149	T155L	155	Missense	distal	6	no	69.762	79.151	EPSD	COSMIC	66.906	Up-regulation
Other_PEK_PKR_EIF2AK2_ST	P04637	TP53	P19525	EIF2AK2	S149	G154A	154	Missense	distal	5	no	69.762	66.599	EPSD	COSMIC	66.906	Loss
Other_PEK_PKR_EIF2AK2_ST	P04637	TP53	P19525	EIF2AK2	S149	T150A	150	Missense	proximal	1	no	69.762	72.022	EPSD	COSMIC	66.906	Up-regulation
Other_PEK_PKR_EIF2AK2_ST	P04637	TP53	P19525	EIF2AK2	S149	W146C	146	Missense	distal	-3	no	69.762	68.322	EPSD	COSMIC	66.906	Down-regulation
Other_PEK_PKR_EIF2AK2_ST	P04637	TP53	P19525	EIF2AK2	S149	P153F	153	Missense	distal	4	no	69.762	68.551	EPSD	COSMIC	66.906	Down-regulation
Other_PEK_PKR_EIF2AK2_ST	P04637	TP53	P19525	EIF2AK2	S149	D148Y	148	Missense	proximal	-1	no	69.762	70.149	EPSD	COSMIC	66.906	Up-regulation
Other_PEK_PKR_EIF2AK2_ST	P04637	TP53	P19525	EIF2AK2	S149	G154R	154	Missense	distal	5	no	69.762	69.506	EPSD	COSMIC	66.906	Down-regulation
Other_PEK_PKR_EIF2AK2_ST	P04637	TP53	P19525	EIF2AK2	S269	N263K	263	Missense	distal	-6	no	43.471	67.170	EPSD	COSMIC	66.906	Gain
Other_PEK_PKR_EIF2AK2_ST	P04637	TP53	P19525	EIF2AK2	T304	N310H	310	Missense	distal	6	no	46.175	67.084	EPSD	COSMIC	66.906	Gain
Other_PEK_PKR_EIF2AK2_ST	P04637	TP53	P19525	EIF2AK2	T304	N310D	310	Missense	distal	6	no	46.175	67.828	EPSD	COSMIC	66.906	Gain
Other_PEK_PKR_EIF2AK2_ST	P04637	TP53	P19525	EIF2AK2	S314	Q317R	317	Missense	distal	3	no	66.176	67.467	EPSD	COSMIC	66.906	Gain
Other_PEK_PKR_EIF2AK2_ST	P04637	TP53	P19525	EIF2AK2	S314	N311K	311	Missense	distal	-3	no	66.176	67.398	EPSD	COSMIC	66.906	Gain
Other_PEK_PKR_EIF2AK2_ST	P04637	TP53	P19525	EIF2AK2	S314	Q317K	317	Missense	distal	3	no	66.176	68.781	EPSD	COSMIC	66.906	Gain
Other_PEK_PKR_EIF2AK2_ST	P04637	TP53	P19525	EIF2AK2	S314	P318A	318	Missense	distal	4	no	66.176	67.839	EPSD	COSMIC	66.906	Gain
Other_PEK_PKR_EIF2AK2_ST	P04637	TP53	P19525	EIF2AK2	S314	L308M	308	Missense	distal	-6	no	66.176	81.250	EPSD	COSMIC	66.906	Gain
Other_PEK_PKR_EIF2AK2_ST	P04637	TP53	P19525	EIF2AK2	S314	L308V	308	Missense	distal	-6	no	66.176	80.969	EPSD	COSMIC	66.906	Gain
Other_PEK_PKR_EIF2AK2_ST	P04637	TP53	P19525	EIF2AK2	S314	K319R	319	Missense	distal	5	no	66.176	68.741	EPSD	COSMIC	66.906	Gain
Other_PEK_PKR_EIF2AK2_ST	P04637	TP53	P19525	EIF2AK2	S314	T312A	312	Missense	proximal	-2	no	66.176	67.065	EPSD	COSMIC	66.906	Gain
Other_PEK_PKR_EIF2AK2_ST	P04637	TP53	P19525	EIF2AK2	S314	Q317P	317	Missense	distal	3	no	66.176	68.809	EPSD	COSMIC	66.906	Gain
TK_Eph_EPHA2_Y	P29317	EPHA2	P29317	EPHA2	Y575	E580Q	580	Missense	distal	5	no	3.036	3.015	EPSD;PhosphoSitePlus	COSMIC	1.229	Down-regulation
TK_Eph_EPHA2_Y	P29317	EPHA2	P29317	EPHA2	Y588	P584S	584	Missense	distal	-4	no	2.253	2.166	EPSD;PhosphoSitePlus	COSMIC	1.229	Down-regulation
TK_Eph_EPHA2_Y	P29317	EPHA2	P29317	EPHA2	Y628	A621V	621	Missense	distal	-7	no	2.273	2.343	EPSD;PhosphoSitePlus	COSMIC	1.229	Up-regulation
TK_Eph_EPHA2_Y	P29317	EPHA2	P29317	EPHA2	Y628	S635F	635	Missense	distal	7	no	2.273	2.396	EPSD;PhosphoSitePlus	COSMIC	1.229	Up-regulation
TK_Eph_EPHA2_Y	P29317	EPHA2	P29317	EPHA2	Y694	M688L	688	Missense	distal	-6	no	2.212	2.201	EPSD;PhosphoSitePlus	COSMIC	1.229	Down-regulation
TK_Eph_EPHA2_Y	P29317	EPHA2	P29317	EPHA2	Y694	M688I	688	Missense	distal	-6	no	2.212	2.178	EPSD;PhosphoSitePlus	COSMIC	1.229	Down-regulation
TK_Eph_EPHA2_Y	P29317	EPHA2	P29317	EPHA2	Y694	A699S	699	Missense	distal	5	no	2.212	2.162	EPSD;PhosphoSitePlus	COSMIC	1.229	Down-regulation
TK_Eph_EPHA2_Y	P29317	EPHA2	P29317	EPHA2	Y735	D739N	739	Missense	distal	4	no	3.040	3.056	EPSD;PhosphoSitePlus	COSMIC	1.229	Up-regulation
TK_Eph_EPHA2_Y	P29317	EPHA2	P29317	EPHA2	Y735	V736M	736	Missense	proximal	1	no	3.040	2.954	EPSD;PhosphoSitePlus	COSMIC	1.229	Down-regulation
TK_Eph_EPHA2_Y	P29317	EPHA2	P29317	EPHA2	Y735	A741V	741	Missense	distal	6	no	3.040	3.041	EPSD;PhosphoSitePlus	COSMIC	1.229	Up-regulation
TK_Eph_EPHA2_Y	P29317	EPHA2	P29317	EPHA2	Y772	G777S	777	Missense	distal	5	no	2.847	2.797	PhosphoSitePlus;EPSD	COSMIC	1.229	Down-regulation
TK_Eph_EPHA2_Y	P29317	EPHA2	P29317	EPHA2	Y921	A928D	928	Missense	distal	7	no	2.307	2.345	EPSD;PhosphoSitePlus	COSMIC;GDSC;CCLE	1.229	Up-regulation
TK_Eph_EPHA2_Y	O14493	CLDN4	P29317	EPHA2	Y208	R201G	201	Missense	distal	-7	no	1.975	1.912	PhosphoSitePlus	COSMIC	1.229	Down-regulation
CAMK_CAMKL_LKB_STK11_ST	P60484	PTEN	Q15831	STK11	T321	L325P	325	Missense	distal	4	no	21.450	21.245	EPSD	COSMIC	16.403	Down-regulation
CAMK_CAMKL_LKB_STK11_ST	P60484	PTEN	Q15831	STK11	T321	L325V	325	Missense	distal	4	no	21.450	21.842	EPSD	COSMIC	16.403	Up-regulation
CAMK_CAMKL_LKB_STK11_ST	P60484	PTEN	Q15831	STK11	T321	L318F	318	Missense	distal	-3	no	21.450	21.266	EPSD	COSMIC	16.403	Down-regulation
CAMK_CAMKL_LKB_STK11_ST	P60484	PTEN	Q15831	STK11	T321	A328V	328	Missense	distal	7	no	21.450	21.530	EPSD	COSMIC	16.403	Up-regulation
CAMK_CAMKL_LKB_STK11_ST	P60484	PTEN	Q15831	STK11	T321	L325H	325	Missense	distal	4	no	21.450	21.415	EPSD	COSMIC	16.403	Down-regulation
CAMK_CAMKL_LKB_STK11_ST	P60484	PTEN	Q15831	STK11	T321	L320V	320	Missense	proximal	-1	no	21.450	20.971	EPSD	COSMIC	16.403	Down-regulation
CAMK_CAMKL_LKB_STK11_ST	P60484	PTEN	Q15831	STK11	T321	Y315H	315	Missense	distal	-6	no	21.450	21.429	EPSD	COSMIC	16.403	Down-regulation
CAMK_CAMKL_LKB_STK11_ST	P60484	PTEN	Q15831	STK11	T321	L318P	318	Missense	distal	-3	no	21.450	21.195	EPSD	COSMIC	16.403	Down-regulation
CAMK_CAMKL_LKB_STK11_ST	P60484	PTEN	Q15831	STK11	T321	N323K	323	Missense	proximal	2	no	21.450	23.673	EPSD	COSMIC	16.403	Up-regulation
CAMK_CAMKL_LKB_STK11_ST	P60484	PTEN	Q15831	STK11	T321	D326E	326	Missense	distal	5	no	21.450	21.093	EPSD	COSMIC	16.403	Down-regulation
CAMK_CAMKL_LKB_STK11_ST	P60484	PTEN	Q15831	STK11	T321	D326Y	326	Missense	distal	5	no	21.450	19.628	EPSD	COSMIC	16.403	Down-regulation
CAMK_CAMKL_LKB_STK11_ST	P60484	PTEN	Q15831	STK11	T321	D326V	326	Missense	distal	5	no	21.450	19.742	EPSD	COSMIC	16.403	Down-regulation
CAMK_CAMKL_LKB_STK11_ST	P60484	PTEN	Q15831	STK11	T321	V317G	317	Missense	distal	-4	no	21.450	21.378	EPSD	COSMIC	16.403	Down-regulation
CAMK_CAMKL_LKB_STK11_ST	P60484	PTEN	Q15831	STK11	T321	E314K	314	Missense	distal	-7	no	21.450	22.156	EPSD	COSMIC	16.403	Up-regulation
CAMK_CAMKL_LKB_STK11_ST	P60484	PTEN	Q15831	STK11	T321	T321I	321	Missense	central	0	yes	21.450	0.000	EPSD	COSMIC	16.403	Loss
CAMK_CAMKL_LKB_STK11_ST	P60484	PTEN	Q15831	STK11	T321	N323T	323	Missense	proximal	2	no	21.450	22.832	EPSD	COSMIC	16.403	Up-regulation
CAMK_CAMKL_LKB_STK11_ST	P60484	PTEN	Q15831	STK11	T321	N323M	323	Missense	proximal	2	no	21.450	19.883	EPSD	COSMIC	16.403	Down-regulation
CAMK_CAMKL_LKB_STK11_ST	P60484	PTEN	Q15831	STK11	T350	P357Q	357	Missense	distal	7	no	16.875	16.245	EPSD	COSMIC	16.403	Loss
CAMK_CAMKL_LKB_STK11_ST	P60484	PTEN	Q15831	STK11	T350	P357L	357	Missense	distal	7	no	16.875	15.509	EPSD	COSMIC	16.403	Loss
CAMK_CAMKL_LKB_STK11_ST	P60484	PTEN	Q15831	STK11	T350	P357S	357	Missense	distal	7	no	16.875	16.333	EPSD	COSMIC	16.403	Loss
CAMK_CAMKL_LKB_STK11_ST	P60484	PTEN	Q15831	STK11	T350	Y346C	346	Missense	distal	-4	no	16.875	16.989	EPSD	COSMIC;CCLE	16.403	Up-regulation
CAMK_CAMKL_LKB_STK11_ST	P60484	PTEN	Q15831	STK11	T350	K344R	344	Missense	distal	-6	no	16.875	16.916	EPSD	COSMIC	16.403	Up-regulation
CAMK_CAMKL_LKB_STK11_ST	P60484	PTEN	Q15831	STK11	T350	T348I	348	Missense	proximal	-2	no	16.875	16.094	EPSD	COSMIC	16.403	Loss
CAMK_CAMKL_LKB_STK11_ST	P60484	PTEN	Q15831	STK11	T350	S355L	355	Missense	distal	5	no	16.875	17.200	EPSD	COSMIC	16.403	Up-regulation
CAMK_CAMKL_LKB_STK11_ST	P60484	PTEN	Q15831	STK11	T350	V343G	343	Missense	distal	-7	no	16.875	16.089	EPSD	COSMIC	16.403	Loss
CAMK_CAMKL_LKB_STK11_ST	P60484	PTEN	Q15831	STK11	T350	T348R	348	Missense	proximal	-2	no	16.875	15.905	EPSD	COSMIC	16.403	Loss
CAMK_CAMKL_LKB_STK11_ST	P60484	PTEN	Q15831	STK11	T363	V369G	369	Missense	distal	6	no	25.338	25.905	EPSD	COSMIC	16.403	Up-regulation
CAMK_CAMKL_LKB_STK11_ST	P60484	PTEN	Q15831	STK11	T363	P357Q	357	Missense	distal	-6	no	25.338	25.406	EPSD	COSMIC	16.403	Up-regulation
CAMK_CAMKL_LKB_STK11_ST	P60484	PTEN	Q15831	STK11	T363	V365I	365	Missense	proximal	2	no	25.338	21.320	EPSD	COSMIC	16.403	Down-regulation
CAMK_CAMKL_LKB_STK11_ST	P60484	PTEN	Q15831	STK11	T363	P357L	357	Missense	distal	-6	no	25.338	25.400	EPSD	COSMIC	16.403	Up-regulation
CAMK_CAMKL_LKB_STK11_ST	P60484	PTEN	Q15831	STK11	T363	P357S	357	Missense	distal	-6	no	25.338	25.378	EPSD	COSMIC	16.403	Up-regulation
CAMK_CAMKL_LKB_STK11_ST	P60484	PTEN	Q15831	STK11	T363	S364C	364	Missense	proximal	1	no	25.338	25.333	EPSD	COSMIC	16.403	Down-regulation
CAMK_CAMKL_LKB_STK11_ST	P60484	PTEN	Q15831	STK11	T363	S361N	361	Missense	proximal	-2	no	25.338	22.656	EPSD	COSMIC	16.403	Down-regulation
CAMK_CAMKL_LKB_STK11_ST	P60484	PTEN	Q15831	STK11	T363	E358D	358	Missense	distal	-5	no	25.338	26.064	EPSD	COSMIC	16.403	Up-regulation
CAMK_CAMKL_LKB_STK11_ST	P60484	PTEN	Q15831	STK11	T366	V369G	369	Missense	distal	3	no	12.477	18.902	EPSD	COSMIC	16.403	Gain
CAMK_CAMKL_LKB_STK11_ST	P60484	PTEN	Q15831	STK11	S380	D375N	375	Missense	distal	-5	no	24.486	23.327	PhosphoSitePlus;EPSD	COSMIC	16.403	Down-regulation
CAMK_CAMKL_LKB_STK11_ST	P60484	PTEN	Q15831	STK11	S380	T383I	383	Missense	distal	3	no	24.486	24.011	PhosphoSitePlus;EPSD	COSMIC	16.403	Down-regulation
CAMK_CAMKL_LKB_STK11_ST	P60484	PTEN	Q15831	STK11	S380	D384N	384	Missense	distal	4	no	24.486	24.017	PhosphoSitePlus;EPSD	COSMIC	16.403	Down-regulation
CAMK_CAMKL_LKB_STK11_ST	P60484	PTEN	Q15831	STK11	S380	T382S	382	Missense	proximal	2	no	24.486	23.968	PhosphoSitePlus;EPSD	COSMIC	16.403	Down-regulation
CAMK_CAMKL_LKB_STK11_ST	P60484	PTEN	Q15831	STK11	S380	D384G	384	Missense	distal	4	no	24.486	22.395	PhosphoSitePlus;EPSD	COSMIC	16.403	Down-regulation
CAMK_CAMKL_LKB_STK11_ST	P60484	PTEN	Q15831	STK11	T382	D375N	375	Missense	distal	-7	no	29.208	28.858	EPSD;PhosphoSitePlus	COSMIC	16.403	Down-regulation
CAMK_CAMKL_LKB_STK11_ST	P60484	PTEN	Q15831	STK11	T382	T383I	383	Missense	proximal	1	no	29.208	29.190	EPSD;PhosphoSitePlus	COSMIC	16.403	Down-regulation
CAMK_CAMKL_LKB_STK11_ST	P60484	PTEN	Q15831	STK11	T382	E388K	388	Missense	distal	6	no	29.208	27.269	EPSD;PhosphoSitePlus	COSMIC	16.403	Down-regulation
CAMK_CAMKL_LKB_STK11_ST	P60484	PTEN	Q15831	STK11	T382	D384N	384	Missense	proximal	2	no	29.208	25.055	EPSD;PhosphoSitePlus	COSMIC	16.403	Down-regulation
CAMK_CAMKL_LKB_STK11_ST	P60484	PTEN	Q15831	STK11	T382	D384G	384	Missense	proximal	2	no	29.208	22.369	EPSD;PhosphoSitePlus	COSMIC	16.403	Down-regulation
CAMK_CAMKL_LKB_STK11_ST	P60484	PTEN	Q15831	STK11	T383	T383I	383	Missense	central	0	yes	27.101	0.000	EPSD;PhosphoSitePlus	COSMIC	16.403	Loss
CAMK_CAMKL_LKB_STK11_ST	P60484	PTEN	Q15831	STK11	T383	E388K	388	Missense	distal	5	no	27.101	26.128	EPSD;PhosphoSitePlus	COSMIC	16.403	Down-regulation
CAMK_CAMKL_LKB_STK11_ST	P60484	PTEN	Q15831	STK11	T383	D384N	384	Missense	proximal	1	no	27.101	27.087	EPSD;PhosphoSitePlus	COSMIC	16.403	Down-regulation
CAMK_CAMKL_LKB_STK11_ST	P60484	PTEN	Q15831	STK11	T383	T382S	382	Missense	proximal	-1	no	27.101	27.604	EPSD;PhosphoSitePlus	COSMIC	16.403	Up-regulation
CAMK_CAMKL_LKB_STK11_ST	P60484	PTEN	Q15831	STK11	T383	D384G	384	Missense	proximal	1	no	27.101	27.069	EPSD;PhosphoSitePlus	COSMIC	16.403	Down-regulation
CAMK_CAMKL_LKB_STK11_ST	P60484	PTEN	Q15831	STK11	T398	H397Y	397	Missense	proximal	-1	no	16.887	17.067	EPSD	COSMIC	16.403	Up-regulation
CAMK_CAMKL_LKB_STK11_ST	P60484	PTEN	Q15831	STK11	T398	Q399H	399	Missense	proximal	1	no	16.887	16.890	EPSD	COSMIC	16.403	Up-regulation
CAMK_CAMKL_LKB_STK11_ST	P60484	PTEN	Q15831	STK11	T398	T401I	401	Missense	distal	3	no	16.887	16.413	EPSD	COSMIC	16.403	Down-regulation
CAMK_CAMKL_LKB_STK11_ST	Q7RTN6	STRADA	Q15831	STK11	S52	E57Q	57	Missense	distal	5	no	22.120	20.948	EPSD	COSMIC	16.403	Down-regulation
CAMK_CAMKL_LKB_STK11_ST	Q7RTN6	STRADA	Q15831	STK11	T329	R333C	333	Missense	distal	4	no	35.152	35.683	PhosphoSitePlus;EPSD	COSMIC	16.403	Up-regulation
CAMK_CAMKL_LKB_STK11_ST	Q7RTN6	STRADA	Q15831	STK11	T329	R333W	333	Missense	distal	4	no	35.152	35.270	PhosphoSitePlus;EPSD	COSMIC	16.403	Up-regulation
CAMK_CAMKL_LKB_STK11_ST	Q7RTN6	STRADA	Q15831	STK11	T329	T331I	331	Missense	proximal	2	no	35.152	31.384	PhosphoSitePlus;EPSD	COSMIC	16.403	Down-regulation
CAMK_CAMKL_LKB_STK11_ST	Q7RTN6	STRADA	Q15831	STK11	T329	S326N	326	Missense	distal	-3	no	35.152	35.105	PhosphoSitePlus;EPSD	COSMIC	16.403	Down-regulation
CAMK_CAMKL_LKB_STK11_ST	Q7RTN6	STRADA	Q15831	STK11	T329	T328N	328	Missense	proximal	-1	no	35.152	35.489	PhosphoSitePlus;EPSD	COSMIC	16.403	Up-regulation
CAMK_CAMKL_LKB_STK11_ST	Q7RTN6	STRADA	Q15831	STK11	T419	G413E	413	Missense	distal	-6	no	30.557	30.547	EPSD;PhosphoSitePlus	COSMIC	16.403	Down-regulation
CAMK_CAMKL_LKB_STK11_ST	Q7RTN6	STRADA	Q15831	STK11	T419	L421M	421	Missense	proximal	2	no	30.557	31.501	EPSD;PhosphoSitePlus	COSMIC	16.403	Up-regulation
CAMK_CAMKL_LKB_STK11_ST	Q13485	SMAD4	Q15831	STK11	T77	T77I	77	Missense	central	0	yes	32.038	0.000	PhosphoSitePlus	COSMIC	16.403	Loss
CAMK_CAMKL_LKB_STK11_ST	Q13485	SMAD4	Q15831	STK11	T77	T77A	77	Missense	central	0	yes	32.038	0.000	PhosphoSitePlus	COSMIC	16.403	Loss
CAMK_CAMKL_LKB_STK11_ST	Q13485	SMAD4	Q15831	STK11	T77	C71F	71	Missense	distal	-6	no	32.038	32.086	PhosphoSitePlus	COSMIC	16.403	Up-regulation
CAMK_CAMKL_LKB_STK11_ST	Q13485	SMAD4	Q15831	STK11	T77	R76I	76	Missense	proximal	-1	no	32.038	31.314	PhosphoSitePlus	COSMIC	16.403	Down-regulation
CAMK_CAMKL_LKB_STK11_ST	Q13485	SMAD4	Q15831	STK11	T77	R81G	81	Missense	distal	4	no	32.038	31.368	PhosphoSitePlus	COSMIC	16.403	Down-regulation
CAMK_CAMKL_LKB_STK11_ST	Q13485	SMAD4	Q15831	STK11	T77	D79N	79	Missense	proximal	2	no	32.038	27.885	PhosphoSitePlus	COSMIC	16.403	Down-regulation
CAMK_CAMKL_LKB_STK11_ST	Q13485	SMAD4	Q15831	STK11	S171	L172M	172	Missense	proximal	1	no	23.775	23.794	EPSD	COSMIC	16.403	Up-regulation
CAMK_CAMKL_LKB_STK11_ST	Q13485	SMAD4	Q15831	STK11	S171	E167D	167	Missense	distal	-4	no	23.775	23.855	EPSD	COSMIC	16.403	Up-regulation
CAMK_CAMKL_LKB_STK11_ST	Q13485	SMAD4	Q15831	STK11	S171	G176E	176	Missense	distal	5	no	23.775	24.931	EPSD	COSMIC	16.403	Up-regulation
CAMK_CAMKL_LKB_STK11_ST	Q13485	SMAD4	Q15831	STK11	S171	P170A	170	Missense	proximal	-1	no	23.775	24.381	EPSD	COSMIC	16.403	Up-regulation
CAMK_CAMKL_LKB_STK11_ST	Q13485	SMAD4	Q15831	STK11	S171	H177Y	177	Missense	distal	6	no	23.775	22.940	EPSD	COSMIC	16.403	Down-regulation
CAMK_CAMKL_LKB_STK11_ST	Q13485	SMAD4	Q15831	STK11	S171	E175G	175	Missense	distal	4	no	23.775	23.935	EPSD	COSMIC	16.403	Up-regulation
CAMK_CAMKL_LKB_STK11_ST	Q13485	SMAD4	Q15831	STK11	S171	D165N	165	Missense	distal	-6	no	23.775	23.824	EPSD	COSMIC	16.403	Up-regulation
CAMK_CAMKL_LKB_STK11_ST	Q13485	SMAD4	Q15831	STK11	S171	S173F	173	Missense	proximal	2	no	23.775	20.015	EPSD	COSMIC	16.403	Down-regulation
CAMK_CAMKL_LKB_STK11_ST	P27448	MARK3	Q15831	STK11	T204	T211R	211	Missense	distal	7	no	26.250	25.516	EPSD	COSMIC	16.403	Down-regulation
CAMK_CAMKL_LKB_STK11_ST	P27448	MARK3	Q15831	STK11	T204	N201K	201	Missense	distal	-3	no	26.250	26.385	EPSD	COSMIC	16.403	Up-regulation
CAMK_CAMKL_LKB_STK11_ST	P27448	MARK3	Q15831	STK11	T204	G207D	207	Missense	distal	3	no	26.250	26.526	EPSD	COSMIC	16.403	Up-regulation
CAMK_CAMKL_LKB_STK11_ST	P27448	MARK3	Q15831	STK11	T211	T211R	211	Missense	central	0	yes	61.854	0.000	EPSD;PhosphoSitePlus	COSMIC	16.403	Loss
CAMK_CAMKL_LKB_STK11_ST	P27448	MARK3	Q15831	STK11	T211	G207D	207	Missense	distal	-4	no	61.854	62.041	EPSD;PhosphoSitePlus	COSMIC	16.403	Up-regulation
CAMK_CAMKL_LKB_STK11_ST	P27448	MARK3	Q15831	STK11	S215	T211R	211	Missense	distal	-4	no	22.083	21.496	PhosphoSitePlus;EPSD	COSMIC	16.403	Down-regulation
CAMK_CAMKL_LKB_STK11_ST	P27448	MARK3	Q15831	STK11	T497	P493H	493	Missense	distal	-4	no	28.512	28.286	EPSD	COSMIC	16.403	Down-regulation
CAMK_CAMKL_LKB_STK11_ST	P27448	MARK3	Q15831	STK11	T497	S495N	495	Missense	proximal	-2	no	28.512	25.831	EPSD	COSMIC	16.403	Down-regulation
CAMK_CAMKL_LKB_STK11_ST	P27448	MARK3	Q15831	STK11	T514	S511N	511	Missense	distal	-3	no	25.152	25.105	EPSD	COSMIC	16.403	Down-regulation
CAMK_CAMKL_LKB_STK11_ST	P27448	MARK3	Q15831	STK11	T515	S511N	511	Missense	distal	-4	no	21.939	22.454	EPSD	COSMIC	16.403	Up-regulation
CAMK_CAMKL_LKB_STK11_ST	P27448	MARK3	Q15831	STK11	T574	G579W	579	Missense	distal	5	no	19.679	19.012	EPSD	COSMIC	16.403	Down-regulation
CAMK_CAMKL_LKB_STK11_ST	P27448	MARK3	Q15831	STK11	S663	R656C	656	Missense	distal	-7	no	20.973	21.845	EPSD	COSMIC	16.403	Up-regulation
CAMK_CAMKL_LKB_STK11_ST	P27448	MARK3	Q15831	STK11	S663	L658P	658	Missense	distal	-5	no	20.973	23.515	EPSD	COSMIC	16.403	Up-regulation
CAMK_CAMKL_LKB_STK11_ST	P27448	MARK3	Q15831	STK11	S663	W662L	662	Missense	proximal	-1	no	20.973	21.411	EPSD	COSMIC	16.403	Up-regulation
CAMK_CAMKL_LKB_STK11_ST	P27448	MARK3	Q15831	STK11	S663	R659C	659	Missense	distal	-4	no	20.973	21.370	EPSD	COSMIC	16.403	Up-regulation
CAMK_CAMKL_LKB_STK11_ST	Q8TDC3	BRSK1	Q15831	STK11	T189	S190N	190	Missense	proximal	1	no	58.183	58.188	EPSD;PhosphoSitePlus	COSMIC	16.403	Up-regulation
CAMK_CAMKL_LKB_STK11_ST	Q8TDC3	BRSK1	Q15831	STK11	T189	P194L	194	Missense	distal	5	no	58.183	58.046	EPSD;PhosphoSitePlus	COSMIC	16.403	Down-regulation
CAMK_CAMKL_LKB_STK11_ST	Q8TDC3	BRSK1	Q15831	STK11	T189	G183E	183	Missense	distal	-6	no	58.183	58.173	EPSD;PhosphoSitePlus	COSMIC	16.403	Down-regulation
CAMK_CAMKL_LKB_STK11_ST	Q8TDC3	BRSK1	Q15831	STK11	S527	P528L	528	Missense	proximal	1	no	27.249	27.255	EPSD	COSMIC	16.403	Up-regulation
CAMK_CAMKL_LKB_STK11_ST	Q8TDC3	BRSK1	Q15831	STK11	S527	R525W	525	Missense	proximal	-2	no	27.249	25.233	EPSD	COSMIC	16.403	Down-regulation
CAMK_CAMKL_LKB_STK11_ST	Q8TDC3	BRSK1	Q15831	STK11	S527	T523M	523	Missense	distal	-4	no	27.249	27.002	EPSD	COSMIC	16.403	Down-regulation
CAMK_CAMKL_LKB_STK11_ST	Q8TDC3	BRSK1	Q15831	STK11	S527	G530R	530	Missense	distal	3	no	27.249	20.763	EPSD	COSMIC	16.403	Down-regulation
CAMK_CAMKL_LKB_STK11_ST	Q8TDC3	BRSK1	Q15831	STK11	T529	P528L	528	Missense	proximal	-1	no	17.319	18.218	EPSD	COSMIC	16.403	Up-regulation
CAMK_CAMKL_LKB_STK11_ST	Q8TDC3	BRSK1	Q15831	STK11	T529	R525W	525	Missense	distal	-4	no	17.319	17.375	EPSD	COSMIC	16.403	Up-regulation
CAMK_CAMKL_LKB_STK11_ST	Q8TDC3	BRSK1	Q15831	STK11	T529	T523M	523	Missense	distal	-6	no	17.319	17.370	EPSD	COSMIC	16.403	Up-regulation
CAMK_CAMKL_LKB_STK11_ST	Q8TDC3	BRSK1	Q15831	STK11	T529	G530R	530	Missense	proximal	1	no	17.319	17.311	EPSD	COSMIC	16.403	Down-regulation
CAMK_CAMKL_LKB_STK11_ST	Q8TDC3	BRSK1	Q15831	STK11	T531	P528L	528	Missense	distal	-3	no	24.346	24.601	EPSD	COSMIC	16.403	Up-regulation
CAMK_CAMKL_LKB_STK11_ST	Q8TDC3	BRSK1	Q15831	STK11	T531	R525W	525	Missense	distal	-6	no	24.346	24.321	EPSD	COSMIC	16.403	Down-regulation
CAMK_CAMKL_LKB_STK11_ST	Q8TDC3	BRSK1	Q15831	STK11	T531	G530R	530	Missense	proximal	-1	no	24.346	24.734	EPSD	COSMIC	16.403	Up-regulation
CAMK_CAMKL_LKB_STK11_ST	Q8TDC3	BRSK1	Q15831	STK11	T772	L770P	770	Missense	proximal	-2	no	21.356	16.968	EPSD	COSMIC	16.403	Down-regulation
CAMK_CAMKL_LKB_STK11_ST	Q6UUV9	CRTC1	Q15831	STK11	T163	S167F	167	Missense	distal	4	no	19.884	19.904	EPSD	COSMIC	16.403	Up-regulation
CAMK_CAMKL_LKB_STK11_ST	Q6UUV9	CRTC1	Q15831	STK11	T163	T163M	163	Missense	central	0	yes	19.884	0.000	EPSD	COSMIC	16.403	Loss
CAMK_CAMKL_LKB_STK11_ST	Q6UUV9	CRTC1	Q15831	STK11	T163	P162L	162	Missense	proximal	-1	no	19.884	20.783	EPSD	COSMIC	16.403	Up-regulation
CAMK_CAMKL_LKB_STK11_ST	Q6UUV9	CRTC1	Q15831	STK11	T163	P162S	162	Missense	proximal	-1	no	19.884	20.393	EPSD	COSMIC	16.403	Up-regulation
CAMK_CAMKL_LKB_STK11_ST	Q6UUV9	CRTC1	Q15831	STK11	S572	T578I	578	Missense	distal	6	no	18.026	17.156	EPSD	COSMIC	16.403	Down-regulation
CAMK_CAMKL_LKB_STK11_ST	Q6UUV9	CRTC1	Q15831	STK11	S572	S572C	572	Missense	central	0	yes	18.026	0.000	EPSD	COSMIC	16.403	Loss
CAMK_CAMKL_LKB_STK11_ST	Q15831	STK11	Q15831	STK11	T71	R74G	74	Missense	distal	3	no	15.629	22.115	EPSD	COSMIC	16.403	Gain
CAMK_CAMKL_LKB_STK11_ST	Q15831	STK11	Q15831	STK11	T185	G187S	187	Missense	proximal	2	no	34.196	37.745	EPSD;PhosphoSitePlus	COSMIC	16.403	Up-regulation
CAMK_CAMKL_LKB_STK11_ST	Q15831	STK11	Q15831	STK11	T185	L190R	190	Missense	distal	5	no	34.196	33.883	EPSD;PhosphoSitePlus	COSMIC	16.403	Down-regulation
CAMK_CAMKL_LKB_STK11_ST	Q15831	STK11	Q15831	STK11	T185	P179L	179	Missense	distal	-6	no	34.196	34.258	EPSD;PhosphoSitePlus	COSMIC	16.403	Up-regulation
CAMK_CAMKL_LKB_STK11_ST	Q15831	STK11	Q15831	STK11	T185	G180V	180	Missense	distal	-5	no	34.196	32.812	EPSD;PhosphoSitePlus	COSMIC	16.403	Down-regulation
CAMK_CAMKL_LKB_STK11_ST	Q15831	STK11	Q15831	STK11	T185	N181S	181	Missense	distal	-4	no	34.196	33.681	EPSD;PhosphoSitePlus	COSMIC	16.403	Down-regulation
CAMK_CAMKL_LKB_STK11_ST	Q15831	STK11	Q15831	STK11	T185	T186S	186	Missense	proximal	1	no	34.196	34.170	EPSD;PhosphoSitePlus	COSMIC	16.403	Down-regulation
CAMK_CAMKL_LKB_STK11_ST	Q15831	STK11	Q15831	STK11	T185	L184F	184	Missense	proximal	-1	no	34.196	33.885	EPSD;PhosphoSitePlus	COSMIC	16.403	Down-regulation
CAMK_CAMKL_LKB_STK11_ST	Q15831	STK11	Q15831	STK11	T185	G180R	180	Missense	distal	-5	no	34.196	32.732	EPSD;PhosphoSitePlus	COSMIC	16.403	Down-regulation
CAMK_CAMKL_LKB_STK11_ST	Q15831	STK11	Q15831	STK11	T185	P179S	179	Missense	distal	-6	no	34.196	34.235	EPSD;PhosphoSitePlus	COSMIC;GDSC;CCLE	16.403	Up-regulation
CAMK_CAMKL_LKB_STK11_ST	Q15831	STK11	Q15831	STK11	T185	N181T	181	Missense	distal	-4	no	34.196	34.148	EPSD;PhosphoSitePlus	COSMIC	16.403	Down-regulation
CAMK_CAMKL_LKB_STK11_ST	Q15831	STK11	Q15831	STK11	T185	G180E	180	Missense	distal	-5	no	34.196	33.509	EPSD;PhosphoSitePlus	COSMIC	16.403	Down-regulation
CAMK_CAMKL_LKB_STK11_ST	Q15831	STK11	Q15831	STK11	T189	G187S	187	Missense	proximal	-2	no	36.410	42.188	EPSD;PhosphoSitePlus	COSMIC	16.403	Up-regulation
CAMK_CAMKL_LKB_STK11_ST	Q15831	STK11	Q15831	STK11	T189	L190R	190	Missense	proximal	1	no	36.410	36.402	EPSD;PhosphoSitePlus	COSMIC	16.403	Down-regulation
CAMK_CAMKL_LKB_STK11_ST	Q15831	STK11	Q15831	STK11	T189	D194V	194	Missense	distal	5	no	36.410	34.702	EPSD;PhosphoSitePlus	COSMIC	16.403	Down-regulation
CAMK_CAMKL_LKB_STK11_ST	Q15831	STK11	Q15831	STK11	T189	G196R	196	Missense	distal	7	no	36.410	35.530	EPSD;PhosphoSitePlus	COSMIC	16.403	Down-regulation
CAMK_CAMKL_LKB_STK11_ST	Q15831	STK11	Q15831	STK11	T189	G196D	196	Missense	distal	7	no	36.410	36.208	EPSD;PhosphoSitePlus	COSMIC	16.403	Down-regulation
CAMK_CAMKL_LKB_STK11_ST	Q15831	STK11	Q15831	STK11	T189	D194G	194	Missense	distal	5	no	36.410	34.897	EPSD;PhosphoSitePlus	COSMIC	16.403	Down-regulation
CAMK_CAMKL_LKB_STK11_ST	Q15831	STK11	Q15831	STK11	T189	T186S	186	Missense	distal	-3	no	36.410	36.159	EPSD;PhosphoSitePlus	COSMIC	16.403	Down-regulation
CAMK_CAMKL_LKB_STK11_ST	Q15831	STK11	Q15831	STK11	T189	L184F	184	Missense	distal	-5	no	36.410	37.900	EPSD;PhosphoSitePlus	COSMIC	16.403	Up-regulation
CAMK_CAMKL_LKB_STK11_ST	Q15831	STK11	Q15831	STK11	T336	W332R	332	Missense	distal	-4	no	31.420	31.364	EPSD;PhosphoSitePlus	COSMIC	16.403	Down-regulation
CAMK_CAMKL_LKB_STK11_ST	Q15831	STK11	Q15831	STK11	T336	M335T	335	Missense	proximal	-1	no	31.420	30.764	EPSD;PhosphoSitePlus	COSMIC	16.403	Down-regulation
CAMK_CAMKL_LKB_STK11_ST	Q15831	STK11	Q15831	STK11	T336	M335I	335	Missense	proximal	-1	no	31.420	30.847	EPSD;PhosphoSitePlus	COSMIC	16.403	Down-regulation
CAMK_CAMKL_LKB_STK11_ST	Q15831	STK11	Q15831	STK11	T336	R333H	333	Missense	distal	-3	no	31.420	31.397	EPSD;PhosphoSitePlus	COSMIC	16.403	Down-regulation
CAMK_CAMKL_LKB_STK11_ST	Q15831	STK11	Q15831	STK11	T336	R331Q	331	Missense	distal	-5	no	31.420	30.926	EPSD;PhosphoSitePlus	COSMIC	16.403	Down-regulation
CAMK_CAMKL_LKB_STK11_ST	Q15831	STK11	Q15831	STK11	T363	P369L	369	Missense	distal	6	no	33.775	32.057	EPSD;PhosphoSitePlus	COSMIC	16.403	Down-regulation
CAMK_CAMKL_LKB_STK11_ST	Q15831	STK11	Q15831	STK11	T363	Q364K	364	Missense	proximal	1	no	33.775	33.797	EPSD;PhosphoSitePlus	COSMIC	16.403	Up-regulation
CAMK_CAMKL_LKB_STK11_ST	Q15831	STK11	Q15831	STK11	T363	T367M	367	Missense	distal	4	no	33.775	33.252	EPSD;PhosphoSitePlus	COSMIC	16.403	Down-regulation
CAMK_CAMKL_LKB_STK11_ST	Q15831	STK11	Q15831	STK11	T363	Y362H	362	Missense	proximal	-1	no	33.775	33.595	EPSD;PhosphoSitePlus	COSMIC	16.403	Down-regulation
CAMK_CAMKL_LKB_STK11_ST	Q15831	STK11	Q15831	STK11	T363	V368L	368	Missense	distal	5	no	33.775	34.387	EPSD;PhosphoSitePlus	COSMIC	16.403	Up-regulation
CAMK_CAMKL_LKB_STK11_ST	Q15831	STK11	Q15831	STK11	T363	E357K	357	Missense	distal	-6	no	33.775	33.786	EPSD;PhosphoSitePlus	COSMIC;GDSC;CCLE	16.403	Up-regulation
CAMK_CAMKL_LKB_STK11_ST	Q15831	STK11	Q15831	STK11	T402	A398V	398	Missense	distal	-4	no	28.705	28.628	EPSD;PhosphoSitePlus	COSMIC	16.403	Down-regulation
CAMK_CAMKL_LKB_STK11_ST	Q15831	STK11	Q15831	STK11	T402	A397V	397	Missense	distal	-5	no	28.705	29.120	EPSD;PhosphoSitePlus	COSMIC	16.403	Up-regulation
CAMK_CAMKL_LKB_STK11_ST	Q15831	STK11	Q15831	STK11	T402	T402A	402	Missense	central	0	yes	28.705	0.000	EPSD;PhosphoSitePlus	COSMIC	16.403	Loss
CAMK_CAMKL_LKB_STK11_ST	Q15831	STK11	Q15831	STK11	T402	Q399P	399	Missense	distal	-3	no	28.705	28.672	EPSD;PhosphoSitePlus	COSMIC	16.403	Down-regulation
CAMK_CAMKL_LKB_STK11_ST	Q15831	STK11	Q15831	STK11	T402	R409Q	409	Missense	distal	7	no	28.705	28.662	EPSD;PhosphoSitePlus	COSMIC	16.403	Down-regulation
CAMK_CAMKL_LKB_STK11_ST	Q15831	STK11	Q15831	STK11	T402	R409W	409	Missense	distal	7	no	28.705	29.293	EPSD;PhosphoSitePlus	COSMIC	16.403	Up-regulation
CAMK_CAMKL_LKB_STK11_ST	Q15831	STK11	Q15831	STK11	S428	R425W	425	Missense	distal	-3	no	18.801	18.726	PhosphoSitePlus;EPSD	COSMIC	16.403	Down-regulation
CAMK_CAMKL_LKB_STK11_ST	Q15831	STK11	Q15831	STK11	S428	S428L	428	Missense	central	0	yes	18.801	0.000	PhosphoSitePlus;EPSD	COSMIC	16.403	Loss
CAMK_CAMKL_LKB_STK11_ST	Q15831	STK11	Q15831	STK11	S428	R425H	425	Missense	distal	-3	no	18.801	18.779	PhosphoSitePlus;EPSD	COSMIC;CCLE	16.403	Down-regulation
CAMK_CAMKL_LKB_STK11_ST	Q15831	STK11	Q15831	STK11	S428	R425P	425	Missense	distal	-3	no	18.801	18.747	PhosphoSitePlus;EPSD	COSMIC	16.403	Down-regulation
CAMK_CAMKL_LKB_STK11_ST	Q15831	STK11	Q15831	STK11	S428	R426W	426	Missense	proximal	-2	no	18.801	16.786	PhosphoSitePlus;EPSD	COSMIC	16.403	Down-regulation
CAMK_CAMKL_LKB_STK11_ST	P57059	SIK1	Q15831	STK11	T182	P187L	187	Missense	distal	5	no	55.113	54.976	PhosphoSitePlus	COSMIC	16.403	Down-regulation
CAMK_CAMKL_LKB_STK11_ST	P57059	SIK1	Q15831	STK11	T182	P188R	188	Missense	distal	6	no	55.113	53.467	PhosphoSitePlus	COSMIC;GDSC;CCLE	16.403	Down-regulation
CAMK_CAMKL_LKB_STK11_ST	P57059	SIK1	Q15831	STK11	T182	G177E	177	Missense	distal	-5	no	55.113	54.426	PhosphoSitePlus	COSMIC	16.403	Down-regulation
CAMK_CAMKL_LKB_STK11_ST	P57059	SIK1	Q15831	STK11	T182	P188L	188	Missense	distal	6	no	55.113	53.395	PhosphoSitePlus	COSMIC	16.403	Down-regulation
CAMK_CAMKL_LKB_STK11_ST	P57059	SIK1	Q15831	STK11	T182	P179L	179	Missense	distal	-3	no	55.113	55.368	PhosphoSitePlus	COSMIC	16.403	Up-regulation
CAMK_CAMKL_LKB_STK11_ST	P57059	SIK1	Q15831	STK11	S186	P187L	187	Missense	proximal	1	no	19.794	19.801	EPSD	COSMIC	16.403	Up-regulation
CAMK_CAMKL_LKB_STK11_ST	P57059	SIK1	Q15831	STK11	S186	P188R	188	Missense	proximal	2	no	19.794	15.253	EPSD	COSMIC;GDSC;CCLE	16.403	Loss
CAMK_CAMKL_LKB_STK11_ST	P57059	SIK1	Q15831	STK11	S186	P192L	192	Missense	distal	6	no	19.794	18.076	EPSD	COSMIC	16.403	Down-regulation
CAMK_CAMKL_LKB_STK11_ST	P57059	SIK1	Q15831	STK11	S186	P188L	188	Missense	proximal	2	no	19.794	16.273	EPSD	COSMIC	16.403	Loss
CAMK_CAMKL_LKB_STK11_ST	P57059	SIK1	Q15831	STK11	S186	P179L	179	Missense	distal	-7	no	19.794	19.951	EPSD	COSMIC	16.403	Up-regulation
CAMK_CAMKL_LKB_STK11_ST	P57059	SIK1	Q15831	STK11	S545	P550L	550	Missense	distal	5	no	17.198	17.061	EPSD	COSMIC;GDSC;CCLE	16.403	Down-regulation
CAMK_CAMKL_LKB_STK11_ST	O14744	PRMT5	Q15831	STK11	T144	G145C	145	Missense	proximal	1	no	17.893	17.902	PhosphoSitePlus	COSMIC	16.403	Up-regulation
CAMK_CAMKL_LKB_STK11_ST	O14744	PRMT5	Q15831	STK11	T144	M150I	150	Missense	distal	6	no	17.893	17.007	PhosphoSitePlus	COSMIC	16.403	Down-regulation
CAMK_CAMKL_LKB_STK11_ST	O14744	PRMT5	Q15831	STK11	T173	D166N	166	Missense	distal	-7	no	16.679	16.329	EPSD	COSMIC	16.403	Loss
CAMK_CAMKL_LKB_STK11_ST	O14744	PRMT5	Q15831	STK11	T185	E183D	183	Missense	proximal	-2	no	22.752	22.774	EPSD	COSMIC	16.403	Up-regulation
CAMK_CAMKL_LKB_STK11_ST	O14744	PRMT5	Q15831	STK11	T194	R193W	193	Missense	proximal	-1	no	16.757	16.404	EPSD	COSMIC	16.403	Down-regulation
CAMK_CAMKL_LKB_STK11_ST	O60285	NUAK1	Q15831	STK11	S267	I262T	262	Missense	distal	-5	no	20.927	20.971	EPSD	COSMIC	16.403	Up-regulation
CAMK_CAMKL_LKB_STK11_ST	O60285	NUAK1	Q15831	STK11	S267	G268E	268	Missense	proximal	1	no	20.927	20.916	EPSD	COSMIC	16.403	Down-regulation
CAMK_CAMKL_LKB_STK11_ST	O60285	NUAK1	Q15831	STK11	S267	R271L	271	Missense	distal	4	no	20.927	21.292	EPSD	COSMIC	16.403	Up-regulation
CAMK_CAMKL_LKB_STK11_ST	O60285	NUAK1	Q15831	STK11	S267	R271W	271	Missense	distal	4	no	20.927	21.046	EPSD	COSMIC	16.403	Up-regulation
CAMK_CAMKL_LKB_STK11_ST	O60285	NUAK1	Q15831	STK11	S542	P546H	546	Missense	distal	4	no	24.505	24.675	EPSD	COSMIC	16.403	Up-regulation
CAMK_CAMKL_LKB_STK11_ST	O60285	NUAK1	Q15831	STK11	S542	M536I	536	Missense	distal	-6	no	24.505	24.479	EPSD	COSMIC	16.403	Down-regulation
CAMK_CAMKL_LKB_STK11_ST	O60285	NUAK1	Q15831	STK11	T547	P546H	546	Missense	proximal	-1	no	18.532	18.978	EPSD	COSMIC	16.403	Up-regulation
CAMK_CAMKL_LKB_STK11_ST	O60285	NUAK1	Q15831	STK11	S550	P546H	546	Missense	distal	-4	no	17.108	16.882	EPSD	COSMIC	16.403	Down-regulation
CAMK_CAMKL_LKB_STK11_ST	O60285	NUAK1	Q15831	STK11	S550	G555C	555	Missense	distal	5	no	17.108	17.461	EPSD	COSMIC	16.403	Up-regulation
CAMK_CAMKL_LKB_STK11_ST	Q13153	PAK1	Q15831	STK11	T22	T20I	20	Missense	proximal	-2	no	18.264	17.483	EPSD	COSMIC	16.403	Down-regulation
CAMK_CAMKL_LKB_STK11_ST	Q13153	PAK1	Q15831	STK11	T22	M17I	17	Missense	distal	-5	no	18.264	20.036	EPSD	COSMIC	16.403	Up-regulation
CAMK_CAMKL_LKB_STK11_ST	Q13153	PAK1	Q15831	STK11	T84	I85N	85	Missense	proximal	1	no	21.646	21.643	EPSD	COSMIC	16.403	Down-regulation
CAMK_CAMKL_LKB_STK11_ST	Q13153	PAK1	Q15831	STK11	T84	E82G	82	Missense	proximal	-2	no	21.646	17.686	EPSD	COSMIC	16.403	Down-regulation
CAMK_CAMKL_LKB_STK11_ST	Q13153	PAK1	Q15831	STK11	T84	S79L	79	Missense	distal	-5	no	21.646	20.586	EPSD	COSMIC	16.403	Down-regulation
CAMK_CAMKL_LKB_STK11_ST	Q13153	PAK1	Q15831	STK11	T109	R105C	105	Missense	distal	-4	no	32.353	32.751	PhosphoSitePlus	COSMIC	16.403	Up-regulation
CAMK_CAMKL_LKB_STK11_ST	Q13153	PAK1	Q15831	STK11	T109	S115L	115	Missense	distal	6	no	32.353	32.155	PhosphoSitePlus	COSMIC;CCLE	16.403	Down-regulation
CAMK_CAMKL_LKB_STK11_ST	Q13153	PAK1	Q15831	STK11	T109	N111H	111	Missense	proximal	2	no	32.353	30.763	PhosphoSitePlus	COSMIC;GDSC;CCLE	16.403	Down-regulation
CAMK_CAMKL_LKB_STK11_ST	Q13153	PAK1	Q15831	STK11	T109	E116D	116	Missense	distal	7	no	32.353	32.359	PhosphoSitePlus	COSMIC;CCLE	16.403	Up-regulation
CAMK_CAMKL_LKB_STK11_ST	Q13153	PAK1	Q15831	STK11	T109	R105W	105	Missense	distal	-4	no	32.353	32.409	PhosphoSitePlus	COSMIC	16.403	Up-regulation
CAMK_CAMKL_LKB_STK11_ST	Q13153	PAK1	Q15831	STK11	S199	R203W	203	Missense	distal	4	no	18.471	18.590	EPSD	COSMIC	16.403	Up-regulation
CAMK_CAMKL_LKB_STK11_ST	Q13153	PAK1	Q15831	STK11	S199	K198Q	198	Missense	proximal	-1	no	18.471	18.910	EPSD	COSMIC	16.403	Up-regulation
CAMK_CAMKL_LKB_STK11_ST	Q13153	PAK1	Q15831	STK11	S199	Y201C	201	Missense	proximal	2	no	18.471	23.622	EPSD	COSMIC	16.403	Up-regulation
CAMK_CAMKL_LKB_STK11_ST	Q13153	PAK1	Q15831	STK11	T236	R237P	237	Missense	proximal	1	no	19.750	19.751	EPSD	COSMIC	16.403	Up-regulation
CAMK_CAMKL_LKB_STK11_ST	Q13153	PAK1	Q15831	STK11	T236	K243Q	243	Missense	distal	7	no	19.750	19.734	EPSD	COSMIC	16.403	Down-regulation
CAMK_CAMKL_LKB_STK11_ST	Q13153	PAK1	Q15831	STK11	T236	R237W	237	Missense	proximal	1	no	19.750	19.767	EPSD	COSMIC	16.403	Up-regulation
CAMK_CAMKL_LKB_STK11_ST	Q13153	PAK1	Q15831	STK11	T239	R237P	237	Missense	proximal	-2	no	26.121	26.419	EPSD	COSMIC	16.403	Up-regulation
CAMK_CAMKL_LKB_STK11_ST	Q13153	PAK1	Q15831	STK11	T239	K245R	245	Missense	distal	6	no	26.121	25.385	EPSD	COSMIC	16.403	Down-regulation
CAMK_CAMKL_LKB_STK11_ST	Q13153	PAK1	Q15831	STK11	T239	K243Q	243	Missense	distal	4	no	26.121	25.378	EPSD	COSMIC	16.403	Down-regulation
CAMK_CAMKL_LKB_STK11_ST	Q13153	PAK1	Q15831	STK11	T239	R237W	237	Missense	proximal	-2	no	26.121	24.105	EPSD	COSMIC	16.403	Down-regulation
CAMK_CAMKL_LKB_STK11_ST	Q13153	PAK1	Q15831	STK11	S422	R421W	421	Missense	proximal	-1	no	30.133	29.780	EPSD	COSMIC	16.403	Down-regulation
CAMK_CAMKL_LKB_STK11_ST	Q13153	PAK1	Q15831	STK11	S422	P428L	428	Missense	distal	6	no	30.133	28.414	EPSD	COSMIC	16.403	Down-regulation
CAMK_CAMKL_LKB_STK11_ST	Q13153	PAK1	Q15831	STK11	S422	R421Q	421	Missense	proximal	-1	no	30.133	30.196	EPSD	COSMIC	16.403	Up-regulation
CAMK_CAMKL_LKB_STK11_ST	Q13153	PAK1	Q15831	STK11	S422	M424I	424	Missense	proximal	2	no	30.133	29.315	EPSD	COSMIC	16.403	Down-regulation
CAMK_CAMKL_LKB_STK11_ST	Q13153	PAK1	Q15831	STK11	S422	E417V	417	Missense	distal	-5	no	30.133	29.436	EPSD	COSMIC	16.403	Down-regulation
CAMK_CAMKL_LKB_STK11_ST	Q13153	PAK1	Q15831	STK11	S422	R421K	421	Missense	proximal	-1	no	30.133	29.756	EPSD	COSMIC	16.403	Down-regulation
CAMK_CAMKL_LKB_STK11_ST	Q14680	MELK	Q15831	STK11	T167	H164N	164	Missense	distal	-3	no	44.373	44.478	PhosphoSitePlus	COSMIC	16.403	Up-regulation
CAMK_CAMKL_LKB_STK11_ST	Q14680	MELK	Q15831	STK11	T167	Y163H	163	Missense	distal	-4	no	44.373	44.473	PhosphoSitePlus	COSMIC	16.403	Up-regulation
CAMK_CAMKL_LKB_STK11_ST	Q14680	MELK	Q15831	STK11	T167	Q166L	166	Missense	proximal	-1	no	44.373	44.394	PhosphoSitePlus	COSMIC	16.403	Up-regulation
CAMK_CAMKL_LKB_STK11_ST	Q14680	MELK	Q15831	STK11	T361	A362P	362	Missense	proximal	1	no	26.450	26.422	EPSD	COSMIC	16.403	Down-regulation
CAMK_CAMKL_LKB_STK11_ST	Q14680	MELK	Q15831	STK11	T361	A362T	362	Missense	proximal	1	no	26.450	26.469	EPSD	COSMIC	16.403	Up-regulation
CAMK_CAMKL_LKB_STK11_ST	Q14680	MELK	Q15831	STK11	S431	E437V	437	Missense	distal	6	no	22.659	20.189	EPSD	COSMIC	16.403	Down-regulation
CAMK_CAMKL_LKB_STK11_ST	Q14680	MELK	Q15831	STK11	S431	K434N	434	Missense	distal	3	no	22.659	24.835	EPSD	COSMIC	16.403	Up-regulation
CAMK_CAMKL_LKB_STK11_ST	Q14680	MELK	Q15831	STK11	S431	A432D	432	Missense	proximal	1	no	22.659	22.670	EPSD	COSMIC	16.403	Up-regulation
CAMK_CAMKL_LKB_STK11_ST	Q14680	MELK	Q15831	STK11	S431	E436K	436	Missense	distal	5	no	22.659	21.686	EPSD	COSMIC	16.403	Down-regulation
CAMK_CAMKL_LKB_STK11_ST	Q14680	MELK	Q15831	STK11	S431	T428M	428	Missense	distal	-3	no	22.659	22.523	EPSD	COSMIC	16.403	Down-regulation
CAMK_CAMKL_LKB_STK11_ST	Q14680	MELK	Q15831	STK11	T459	Y464C	464	Missense	distal	5	no	18.552	19.214	EPSD	COSMIC	16.403	Up-regulation
CAMK_CAMKL_LKB_STK11_ST	Q14680	MELK	Q15831	STK11	T459	T460M	460	Missense	proximal	1	no	18.552	18.532	EPSD	COSMIC;GDSC	16.403	Down-regulation
CAMK_CAMKL_LKB_STK11_ST	Q14680	MELK	Q15831	STK11	T459	I457T	457	Missense	proximal	-2	no	18.552	19.333	EPSD	COSMIC	16.403	Up-regulation
CAMK_CAMKL_LKB_STK11_ST	Q14680	MELK	Q15831	STK11	T459	R463H	463	Missense	distal	4	no	18.552	18.883	EPSD	COSMIC	16.403	Up-regulation
CAMK_CAMKL_LKB_STK11_ST	Q13131	PRKAA1	Q15831	STK11	T244	N249H	249	Missense	distal	5	no	17.262	17.441	EPSD	COSMIC	16.403	Up-regulation
CAMK_CAMKL_LKB_STK11_ST	Q13131	PRKAA1	Q15831	STK11	T244	P250H	250	Missense	distal	6	no	17.262	16.363	EPSD	COSMIC	16.403	Loss
CAMK_CAMKL_LKB_STK11_ST	Q13131	PRKAA1	Q15831	STK11	T244	L248F	248	Missense	distal	4	no	17.262	17.064	EPSD	COSMIC	16.403	Down-regulation
CAMK_CAMKL_LKB_STK11_ST	Q13131	PRKAA1	Q15831	STK11	T297	A303D	303	Missense	distal	6	no	16.547	19.283	EPSD	COSMIC	16.403	Up-regulation
CAMK_CAMKL_LKB_STK11_ST	Q13131	PRKAA1	Q15831	STK11	T355	F351L	351	Missense	distal	-4	no	21.212	20.760	EPSD	COSMIC	16.403	Down-regulation
CAMK_CAMKL_LKB_STK11_ST	Q13131	PRKAA1	Q15831	STK11	T355	A354T	354	Missense	proximal	-1	no	21.212	20.612	EPSD	COSMIC	16.403	Down-regulation
CAMK_CAMKL_LKB_STK11_ST	Q13131	PRKAA1	Q15831	STK11	T355	D350N	350	Missense	distal	-5	no	21.212	20.053	EPSD	COSMIC	16.403	Down-regulation
CAMK_CAMKL_LKB_STK11_ST	Q13131	PRKAA1	Q15831	STK11	S496	R501G	501	Missense	distal	5	no	38.291	38.186	EPSD	COSMIC	16.403	Down-regulation
CAMK_CAMKL_LKB_STK11_ST	Q13131	PRKAA1	Q15831	STK11	T526	S524F	524	Missense	proximal	-2	no	23.758	21.035	EPSD	COSMIC	16.403	Down-regulation
CAMK_CAMKL_LKB_STK11_ST	Q13131	PRKAA1	Q15831	STK11	T526	S531F	531	Missense	distal	5	no	23.758	22.398	EPSD	COSMIC	16.403	Down-regulation
CAMK_CAMKL_LKB_STK11_ST	Q96L34	MARK4	Q15831	STK11	S210	E205K	205	Missense	distal	-5	no	17.604	16.740	EPSD	COSMIC	16.403	Down-regulation
CAMK_CAMKL_LKB_STK11_ST	Q96L34	MARK4	Q15831	STK11	S210	T207M	207	Missense	distal	-3	no	17.604	17.468	EPSD	COSMIC	16.403	Down-regulation
CAMK_CAMKL_LKB_STK11_ST	Q96L34	MARK4	Q15831	STK11	S210	S203N	203	Missense	distal	-7	no	17.604	17.751	EPSD	COSMIC;GDSC;CCLE	16.403	Up-regulation
CAMK_CAMKL_LKB_STK11_ST	Q96L34	MARK4	Q15831	STK11	T214	S218N	218	Missense	distal	4	no	60.238	61.042	PhosphoSitePlus	COSMIC	16.403	Up-regulation
CAMK_CAMKL_LKB_STK11_ST	Q96L34	MARK4	Q15831	STK11	T214	T207M	207	Missense	distal	-7	no	60.238	59.258	PhosphoSitePlus	COSMIC	16.403	Down-regulation
CAMK_CAMKL_LKB_STK11_ST	Q96L34	MARK4	Q15831	STK11	S458	A462V	462	Missense	distal	4	no	18.884	18.498	EPSD	COSMIC	16.403	Down-regulation
CAMK_CAMKL_LKB_STK11_ST	Q96L34	MARK4	Q15831	STK11	T497	R491W	491	Missense	distal	-6	no	20.753	20.728	EPSD	COSMIC;CCLE	16.403	Down-regulation
CAMK_CAMKL_LKB_STK11_ST	Q96L34	MARK4	Q15831	STK11	T497	P503S	503	Missense	distal	6	no	20.753	19.233	EPSD	COSMIC	16.403	Down-regulation
CAMK_CAMKL_LKB_STK11_ST	Q96L34	MARK4	Q15831	STK11	T497	P503L	503	Missense	distal	6	no	20.753	19.034	EPSD	COSMIC	16.403	Down-regulation
CAMK_CAMKL_LKB_STK11_ST	Q96L34	MARK4	Q15831	STK11	T568	R561H	561	Missense	distal	-7	no	24.452	25.029	EPSD	COSMIC	16.403	Up-regulation
CAMK_CAMKL_LKB_STK11_ST	P38936	CDKN1A	Q15831	STK11	T80	D87E	87	Missense	distal	7	no	18.169	18.163	PhosphoSitePlus	COSMIC	16.403	Down-regulation
CAMK_CAMKL_LKB_STK11_ST	P38936	CDKN1A	Q15831	STK11	T80	R84Q	84	Missense	distal	4	no	18.169	18.218	PhosphoSitePlus	COSMIC	16.403	Up-regulation
CAMK_CAMKL_LKB_STK11_ST	P38936	CDKN1A	Q15831	STK11	T80	R86G	86	Missense	distal	6	no	18.169	18.941	PhosphoSitePlus	COSMIC	16.403	Up-regulation
CAMK_CAMKL_LKB_STK11_ST	P38936	CDKN1A	Q15831	STK11	T80	G85V	85	Missense	distal	5	no	18.169	17.974	PhosphoSitePlus	COSMIC	16.403	Down-regulation
CAMK_CAMKL_LKB_STK11_ST	P38936	CDKN1A	Q15831	STK11	T80	R86P	86	Missense	distal	6	no	18.169	19.815	PhosphoSitePlus	COSMIC	16.403	Up-regulation
CAMK_CAMKL_LKB_STK11_ST	P38936	CDKN1A	Q15831	STK11	T80	R83W	83	Missense	distal	3	no	18.169	19.989	PhosphoSitePlus	COSMIC	16.403	Up-regulation
CAMK_CAMKL_LKB_STK11_ST	P38936	CDKN1A	Q15831	STK11	T80	Y77N	77	Missense	distal	-3	no	18.169	18.336	PhosphoSitePlus	COSMIC	16.403	Up-regulation
CAMK_CAMKL_LKB_STK11_ST	P38936	CDKN1A	Q15831	STK11	S114	E108Q	108	Missense	distal	-6	no	20.210	20.265	EPSD	COSMIC	16.403	Up-regulation
CAMK_CAMKL_LKB_STK11_ST	P38936	CDKN1A	Q15831	STK11	S114	S114L	114	Missense	central	0	yes	20.210	0.000	EPSD	COSMIC	16.403	Loss
CAMK_CAMKL_LKB_STK11_ST	P38936	CDKN1A	Q15831	STK11	S114	D112V	112	Missense	proximal	-2	no	20.210	19.610	EPSD	COSMIC	16.403	Down-regulation
CAMK_CAMKL_LKB_STK11_ST	P38936	CDKN1A	Q15831	STK11	S114	L113M	113	Missense	proximal	-1	no	20.210	19.974	EPSD	COSMIC	16.403	Down-regulation
CAMK_CAMKL_LKB_STK11_ST	P38936	CDKN1A	Q15831	STK11	S114	D109H	109	Missense	distal	-5	no	20.210	19.158	EPSD	COSMIC	16.403	Down-regulation
CAMK_CAMKL_LKB_STK11_ST	Q8IWQ3	BRSK2	Q15831	STK11	T174	H180Y	180	Missense	distal	6	no	57.881	57.046	PhosphoSitePlus	COSMIC	16.403	Down-regulation
CAMK_CAMKL_LKB_STK11_ST	Q8IWQ3	BRSK2	Q15831	STK11	T174	S178F	178	Missense	distal	4	no	57.881	57.900	PhosphoSitePlus	COSMIC	16.403	Up-regulation
CAMK_CAMKL_LKB_STK11_ST	Q8IWQ3	BRSK2	Q15831	STK11	T174	C176F	176	Missense	proximal	2	no	57.881	49.435	PhosphoSitePlus	COSMIC	16.403	Down-regulation
CAMK_CAMKL_LKB_STK11_ST	Q8IWQ3	BRSK2	Q15831	STK11	T389	V388M	388	Missense	proximal	-1	no	20.572	20.815	EPSD	COSMIC	16.403	Up-regulation
CAMK_CAMKL_LKB_STK11_ST	Q8IWQ3	BRSK2	Q15831	STK11	T389	T389M	389	Missense	central	0	yes	20.572	0.000	EPSD	COSMIC	16.403	Loss
CAMK_CAMKL_LKB_STK11_ST	Q8IWQ3	BRSK2	Q15831	STK11	T389	S382F	382	Missense	distal	-7	no	20.572	20.626	EPSD	COSMIC	16.403	Up-regulation
CAMK_CAMKL_LKB_STK11_ST	Q8IWQ3	BRSK2	Q15831	STK11	T389	P394Q	394	Missense	distal	5	no	20.572	20.002	EPSD	COSMIC	16.403	Down-regulation
CAMK_CAMKL_LKB_STK11_ST	Q8IWQ3	BRSK2	Q15831	STK11	T389	S387I	387	Missense	proximal	-2	no	20.572	19.906	EPSD	COSMIC	16.403	Down-regulation
CAMK_CAMKL_LKB_STK11_ST	Q8IWQ3	BRSK2	Q15831	STK11	T389	S387R	387	Missense	proximal	-2	no	20.572	19.716	EPSD	COSMIC	16.403	Down-regulation
CAMK_CAMKL_LKB_STK11_ST	Q8IWQ3	BRSK2	Q15831	STK11	T389	S393F	393	Missense	distal	4	no	20.572	20.592	EPSD	COSMIC	16.403	Up-regulation
CAMK_CAMKL_LKB_STK11_ST	Q8IWQ3	BRSK2	Q15831	STK11	T443	P440L	440	Missense	distal	-3	no	34.309	34.564	EPSD	COSMIC	16.403	Up-regulation
CAMK_CAMKL_LKB_STK11_ST	Q8IWQ3	BRSK2	Q15831	STK11	T447	P440L	440	Missense	distal	-7	no	28.417	28.574	EPSD	COSMIC	16.403	Up-regulation
CAMK_CAMKL_LKB_STK11_ST	Q8IWQ3	BRSK2	Q15831	STK11	T451	S455N	455	Missense	distal	4	no	18.776	19.579	EPSD	COSMIC	16.403	Up-regulation
CAMK_CAMKL_LKB_STK11_ST	Q8IWQ3	BRSK2	Q15831	STK11	T451	S455G	455	Missense	distal	4	no	18.776	17.957	EPSD	COSMIC	16.403	Down-regulation
CAMK_CAMKL_LKB_STK11_ST	Q8IWQ3	BRSK2	Q15831	STK11	T459	P465L	465	Missense	distal	6	no	27.098	25.379	EPSD	COSMIC	16.403	Down-regulation
CAMK_CAMKL_LKB_STK11_ST	Q8IWQ3	BRSK2	Q15831	STK11	T459	S455N	455	Missense	distal	-4	no	27.098	27.613	EPSD	COSMIC	16.403	Up-regulation
CAMK_CAMKL_LKB_STK11_ST	Q8IWQ3	BRSK2	Q15831	STK11	T459	S455G	455	Missense	distal	-4	no	27.098	27.424	EPSD	COSMIC	16.403	Up-regulation
CAMK_CAMKL_LKB_STK11_ST	Q8IWQ3	BRSK2	Q15831	STK11	T611	L614I	614	Missense	distal	3	no	9.837	20.503	EPSD	COSMIC	16.403	Gain
CAMK_CAMKL_LKB_STK11_ST	Q9P0L2	MARK1	Q15831	STK11	T208	N205D	205	Missense	distal	-3	no	20.448	20.522	EPSD	COSMIC	16.403	Up-regulation
CAMK_CAMKL_LKB_STK11_ST	Q9P0L2	MARK1	Q15831	STK11	T208	F207C	207	Missense	proximal	-1	no	20.448	20.209	EPSD	COSMIC	16.403	Down-regulation
CAMK_CAMKL_LKB_STK11_ST	Q9P0L2	MARK1	Q15831	STK11	T208	E206D	206	Missense	proximal	-2	no	20.448	20.470	EPSD	COSMIC	16.403	Up-regulation
CAMK_CAMKL_LKB_STK11_ST	Q9P0L2	MARK1	Q15831	STK11	T208	V209F	209	Missense	proximal	1	no	20.448	20.436	EPSD	COSMIC	16.403	Down-regulation
CAMK_CAMKL_LKB_STK11_ST	Q9P0L2	MARK1	Q15831	STK11	T215	S219N	219	Missense	distal	4	no	61.517	62.320	PhosphoSitePlus	COSMIC	16.403	Up-regulation
CAMK_CAMKL_LKB_STK11_ST	Q9P0L2	MARK1	Q15831	STK11	T215	V209F	209	Missense	distal	-6	no	61.517	61.543	PhosphoSitePlus	COSMIC	16.403	Up-regulation
CAMK_CAMKL_LKB_STK11_ST	Q9P0L2	MARK1	Q15831	STK11	S219	E226K	226	Missense	distal	7	no	22.096	21.396	EPSD	COSMIC;GDSC;CCLE	16.403	Down-regulation
CAMK_CAMKL_LKB_STK11_ST	Q9P0L2	MARK1	Q15831	STK11	S219	S219N	219	Missense	central	0	yes	22.096	0.000	EPSD	COSMIC	16.403	Loss
CAMK_CAMKL_LKB_STK11_ST	Q9P0L2	MARK1	Q15831	STK11	T282	L287F	287	Missense	distal	5	no	19.417	17.732	EPSD	COSMIC;GDSC;CCLE	16.403	Down-regulation
CAMK_CAMKL_LKB_STK11_ST	Q9P0L2	MARK1	Q15831	STK11	T282	R275C	275	Missense	distal	-7	no	19.417	20.290	EPSD	COSMIC;GDSC;CCLE	16.403	Up-regulation
CAMK_CAMKL_LKB_STK11_ST	Q9P0L2	MARK1	Q15831	STK11	T282	L287I	287	Missense	distal	5	no	19.417	18.941	EPSD	COSMIC	16.403	Down-regulation
CAMK_CAMKL_LKB_STK11_ST	Q9P0L2	MARK1	Q15831	STK11	S486	T487S	487	Missense	proximal	1	no	19.278	19.252	EPSD	COSMIC	16.403	Down-regulation
CAMK_CAMKL_LKB_STK11_ST	Q9P0L2	MARK1	Q15831	STK11	S486	N491S	491	Missense	distal	5	no	19.278	19.311	EPSD	COSMIC	16.403	Up-regulation
CAMK_CAMKL_LKB_STK11_ST	Q9P0L2	MARK1	Q15831	STK11	S486	P489R	489	Missense	distal	3	no	19.278	16.315	EPSD	COSMIC	16.403	Loss
CAMK_CAMKL_LKB_STK11_ST	Q9P0L2	MARK1	Q15831	STK11	S486	N491K	491	Missense	distal	5	no	19.278	19.402	EPSD	COSMIC	16.403	Up-regulation
CAMK_CAMKL_LKB_STK11_ST	Q9P0L2	MARK1	Q15831	STK11	T580	R583T	583	Missense	distal	3	no	12.617	17.275	EPSD	COSMIC;GDSC;CCLE	16.403	Gain
CAMK_CAMKL_LKB_STK11_ST	Q9P0L2	MARK1	Q15831	STK11	T598	A591T	591	Missense	distal	-7	no	16.239	17.169	EPSD	COSMIC	16.403	Gain
CAMK_CAMKL_LKB_STK11_ST	Q9P0L2	MARK1	Q15831	STK11	T598	S593G	593	Missense	distal	-5	no	16.239	17.979	EPSD	COSMIC	16.403	Gain
CAMK_CAMKL_LKB_STK11_ST	Q9P0L2	MARK1	Q15831	STK11	T598	R601W	601	Missense	distal	3	no	16.239	18.060	EPSD	COSMIC	16.403	Gain
CAMK_CAMKL_LKB_STK11_ST	Q9P0L2	MARK1	Q15831	STK11	T613	R620W	620	Missense	distal	7	no	21.439	22.027	EPSD	COSMIC	16.403	Up-regulation
CAMK_CAMKL_LKB_STK11_ST	Q9P0L2	MARK1	Q15831	STK11	T648	T648A	648	Missense	central	0	yes	18.208	0.000	EPSD	COSMIC	16.403	Loss
CAMK_CAMKL_LKB_STK11_ST	Q9P0L2	MARK1	Q15831	STK11	T648	A642S	642	Missense	distal	-6	no	18.208	18.199	EPSD	COSMIC	16.403	Down-regulation
CAMK_CAMKL_LKB_STK11_ST	Q9P0L2	MARK1	Q15831	STK11	S705	R698H	698	Missense	distal	-7	no	21.281	21.857	EPSD	COSMIC	16.403	Up-regulation
CAMK_CAMKL_LKB_STK11_ST	Q9P0L2	MARK1	Q15831	STK11	S705	R701Q	701	Missense	distal	-4	no	21.281	21.410	EPSD	COSMIC	16.403	Up-regulation
CAMK_CAMKL_LKB_STK11_ST	Q9P0L2	MARK1	Q15831	STK11	S705	T709I	709	Missense	distal	4	no	21.281	21.020	EPSD	COSMIC	16.403	Down-regulation
CAMK_CAMKL_LKB_STK11_ST	Q9P0L2	MARK1	Q15831	STK11	S705	R698C	698	Missense	distal	-7	no	21.281	22.153	EPSD	COSMIC;GDSC;CCLE	16.403	Up-regulation
CAMK_CAMKL_LKB_STK11_ST	Q9P0L2	MARK1	Q15831	STK11	S705	S711G	711	Missense	distal	6	no	21.281	21.926	EPSD	COSMIC	16.403	Up-regulation
CAMK_CAMKL_LKB_STK11_ST	P04637	TP53	Q15831	STK11	S15	E11Q	11	Missense	distal	-4	no	16.759	16.337	EPSD;PhosphoSitePlus	COSMIC;GDSC;CCLE	16.403	Loss
CAMK_CAMKL_LKB_STK11_ST	P04637	TP53	Q15831	STK11	S15	S20L	20	Missense	distal	5	no	16.759	17.084	EPSD;PhosphoSitePlus	COSMIC	16.403	Up-regulation
CAMK_CAMKL_LKB_STK11_ST	P04637	TP53	Q15831	STK11	S15	Q16L	16	Missense	proximal	1	no	16.759	16.758	EPSD;PhosphoSitePlus	COSMIC;GDSC;CCLE	16.403	Down-regulation
CAMK_CAMKL_LKB_STK11_ST	P04637	TP53	Q15831	STK11	S15	P13S	13	Missense	proximal	-2	no	16.759	17.317	EPSD;PhosphoSitePlus	COSMIC	16.403	Up-regulation
CAMK_CAMKL_LKB_STK11_ST	P04637	TP53	Q15831	STK11	S15	E17K	17	Missense	proximal	2	no	16.759	17.785	EPSD;PhosphoSitePlus	COSMIC	16.403	Up-regulation
CAMK_CAMKL_LKB_STK11_ST	P04637	TP53	Q15831	STK11	S15	V10I	10	Missense	distal	-5	no	16.759	17.925	EPSD;PhosphoSitePlus	COSMIC	16.403	Up-regulation
CAMK_CAMKL_LKB_STK11_ST	P04637	TP53	Q15831	STK11	S15	P8L	8	Missense	distal	-7	no	16.759	16.916	EPSD;PhosphoSitePlus	COSMIC	16.403	Up-regulation
CAMK_CAMKL_LKB_STK11_ST	P04637	TP53	Q15831	STK11	S15	P8S	8	Missense	distal	-7	no	16.759	17.188	EPSD;PhosphoSitePlus	COSMIC	16.403	Up-regulation
CAMK_CAMKL_LKB_STK11_ST	P04637	TP53	Q15831	STK11	S15	P13L	13	Missense	proximal	-2	no	16.759	21.147	EPSD;PhosphoSitePlus	COSMIC	16.403	Up-regulation
CAMK_CAMKL_LKB_STK11_ST	P04637	TP53	Q15831	STK11	S15	V10G	10	Missense	distal	-5	no	16.759	18.142	EPSD;PhosphoSitePlus	COSMIC	16.403	Up-regulation
CAMK_CAMKL_LKB_STK11_ST	P04637	TP53	Q15831	STK11	S15	T18A	18	Missense	distal	3	no	16.759	11.380	EPSD;PhosphoSitePlus	COSMIC	16.403	Loss
CAMK_CAMKL_LKB_STK11_ST	P04637	TP53	Q15831	STK11	S15	F19S	19	Missense	distal	4	no	16.759	16.739	EPSD;PhosphoSitePlus	COSMIC	16.403	Down-regulation
CAMK_CAMKL_LKB_STK11_ST	P04637	TP53	Q15831	STK11	S15	E17V	17	Missense	proximal	2	no	16.759	17.194	EPSD;PhosphoSitePlus	COSMIC	16.403	Up-regulation
CAMK_CAMKL_LKB_STK11_ST	P04637	TP53	Q15831	STK11	S15	S9G	9	Missense	distal	-6	no	16.759	16.743	EPSD;PhosphoSitePlus	COSMIC	16.403	Down-regulation
CAMK_CAMKL_LKB_STK11_ST	P04637	TP53	Q15831	STK11	S15	T18I	18	Missense	distal	3	no	16.759	16.284	EPSD;PhosphoSitePlus	COSMIC	16.403	Loss
CAMK_CAMKL_LKB_STK11_ST	P04637	TP53	Q15831	STK11	S15	T18K	18	Missense	distal	3	no	16.759	11.625	EPSD;PhosphoSitePlus	COSMIC	16.403	Loss
CAMK_CAMKL_LKB_STK11_ST	P04637	TP53	Q15831	STK11	S15	T18R	18	Missense	distal	3	no	16.759	12.101	EPSD;PhosphoSitePlus	COSMIC	16.403	Loss
CAMK_CAMKL_LKB_STK11_ST	P04637	TP53	Q15831	STK11	S15	S15I	15	Missense	central	0	yes	16.759	0.000	EPSD;PhosphoSitePlus	COSMIC	16.403	Loss
CAMK_CAMKL_LKB_STK11_ST	P04637	TP53	Q15831	STK11	T18	Q16L	16	Missense	proximal	-2	no	12.601	18.442	EPSD	COSMIC;GDSC;CCLE	16.403	Gain
CAMK_CAMKL_LKB_STK11_ST	P04637	TP53	Q15831	STK11	T155	P151N	151	Missense	distal	-4	no	17.567	17.592	EPSD	COSMIC	16.403	Up-regulation
CAMK_CAMKL_LKB_STK11_ST	P04637	TP53	Q15831	STK11	T155	P152A	152	Missense	distal	-3	no	17.567	17.647	EPSD	COSMIC	16.403	Up-regulation
CAMK_CAMKL_LKB_STK11_ST	P04637	TP53	Q15831	STK11	T155	P152T	152	Missense	distal	-3	no	17.567	18.002	EPSD	COSMIC	16.403	Up-regulation
CAMK_CAMKL_LKB_STK11_ST	P04637	TP53	Q15831	STK11	T155	P152H	152	Missense	distal	-3	no	17.567	17.598	EPSD	COSMIC	16.403	Up-regulation
CAMK_CAMKL_LKB_STK11_ST	P04637	TP53	Q15831	STK11	T155	A159S	159	Missense	distal	4	no	17.567	16.572	EPSD	COSMIC	16.403	Down-regulation
CAMK_CAMKL_LKB_STK11_ST	P04637	TP53	Q15831	STK11	T155	P153T	153	Missense	proximal	-2	no	17.567	18.239	EPSD	COSMIC	16.403	Up-regulation
CAMK_CAMKL_LKB_STK11_ST	P04637	TP53	Q15831	STK11	T155	A159T	159	Missense	distal	4	no	17.567	17.183	EPSD	COSMIC	16.403	Down-regulation
CAMK_CAMKL_LKB_STK11_ST	P04637	TP53	Q15831	STK11	T155	P153L	153	Missense	proximal	-2	no	17.567	21.955	EPSD	COSMIC	16.403	Up-regulation
CAMK_CAMKL_LKB_STK11_ST	P04637	TP53	Q15831	STK11	T155	S149P	149	Missense	distal	-6	no	17.567	17.527	EPSD	COSMIC	16.403	Down-regulation
CAMK_CAMKL_LKB_STK11_ST	P04637	TP53	Q15831	STK11	T155	P152K	152	Missense	distal	-3	no	17.567	17.839	EPSD	COSMIC	16.403	Up-regulation
CAMK_CAMKL_LKB_STK11_ST	P04637	TP53	Q15831	STK11	T155	P153S	153	Missense	proximal	-2	no	17.567	18.125	EPSD	COSMIC	16.403	Up-regulation
CAMK_CAMKL_LKB_STK11_ST	P04637	TP53	Q15831	STK11	T155	G154C	154	Missense	proximal	-1	no	17.567	17.491	EPSD	COSMIC	16.403	Down-regulation
CAMK_CAMKL_LKB_STK11_ST	P04637	TP53	Q15831	STK11	T155	S149F	149	Missense	distal	-6	no	17.567	17.590	EPSD	COSMIC	16.403	Up-regulation
CAMK_CAMKL_LKB_STK11_ST	P04637	TP53	Q15831	STK11	T155	G154D	154	Missense	proximal	-1	no	17.567	17.392	EPSD	COSMIC	16.403	Down-regulation
CAMK_CAMKL_LKB_STK11_ST	P04637	TP53	Q15831	STK11	T155	M160K	160	Missense	distal	5	no	17.567	17.364	EPSD	COSMIC	16.403	Down-regulation
CAMK_CAMKL_LKB_STK11_ST	P04637	TP53	Q15831	STK11	T155	M160L	160	Missense	distal	5	no	17.567	17.599	EPSD	COSMIC	16.403	Up-regulation
CAMK_CAMKL_LKB_STK11_ST	P04637	TP53	Q15831	STK11	T155	I162V	162	Missense	distal	7	no	17.567	17.253	EPSD	COSMIC	16.403	Down-regulation
CAMK_CAMKL_LKB_STK11_ST	P04637	TP53	Q15831	STK11	T155	V157I	157	Missense	proximal	2	no	17.567	13.549	EPSD	COSMIC	16.403	Loss
CAMK_CAMKL_LKB_STK11_ST	P04637	TP53	Q15831	STK11	T155	A161G	161	Missense	distal	6	no	17.567	18.018	EPSD	COSMIC	16.403	Up-regulation
CAMK_CAMKL_LKB_STK11_ST	P04637	TP53	Q15831	STK11	T155	D148V	148	Missense	distal	-7	no	17.567	17.259	EPSD	COSMIC	16.403	Down-regulation
CAMK_CAMKL_LKB_STK11_ST	P04637	TP53	Q15831	STK11	T155	I162M	162	Missense	distal	7	no	17.567	17.044	EPSD	COSMIC	16.403	Down-regulation
CAMK_CAMKL_LKB_STK11_ST	P04637	TP53	Q15831	STK11	T155	S149Y	149	Missense	distal	-6	no	17.567	17.577	EPSD	COSMIC	16.403	Up-regulation
CAMK_CAMKL_LKB_STK11_ST	P04637	TP53	Q15831	STK11	T155	M160V	160	Missense	distal	5	no	17.567	16.987	EPSD	COSMIC	16.403	Down-regulation
CAMK_CAMKL_LKB_STK11_ST	P04637	TP53	Q15831	STK11	T155	A159D	159	Missense	distal	4	no	17.567	17.844	EPSD	COSMIC;GDSC;CCLE	16.403	Up-regulation
CAMK_CAMKL_LKB_STK11_ST	P04637	TP53	Q15831	STK11	T155	T150I	150	Missense	distal	-5	no	17.567	17.522	EPSD	COSMIC	16.403	Down-regulation
CAMK_CAMKL_LKB_STK11_ST	P04637	TP53	Q15831	STK11	T155	S149T	149	Missense	distal	-6	no	17.567	17.516	EPSD	COSMIC	16.403	Down-regulation
CAMK_CAMKL_LKB_STK11_ST	P04637	TP53	Q15831	STK11	T155	R156S	156	Missense	proximal	1	no	17.567	17.589	EPSD	COSMIC	16.403	Up-regulation
CAMK_CAMKL_LKB_STK11_ST	P04637	TP53	Q15831	STK11	T155	D148E	148	Missense	distal	-7	no	17.567	16.789	EPSD	COSMIC	16.403	Down-regulation
CAMK_CAMKL_LKB_STK11_ST	P04637	TP53	Q15831	STK11	T155	T155A	155	Missense	central	0	yes	17.567	0.000	EPSD	COSMIC	16.403	Loss
CAMK_CAMKL_LKB_STK11_ST	P04637	TP53	Q15831	STK11	T155	G154I	154	Missense	proximal	-1	no	17.567	17.231	EPSD	COSMIC	16.403	Down-regulation
CAMK_CAMKL_LKB_STK11_ST	P04637	TP53	Q15831	STK11	T155	D148G	148	Missense	distal	-7	no	17.567	16.473	EPSD	COSMIC	16.403	Down-regulation
CAMK_CAMKL_LKB_STK11_ST	P04637	TP53	Q15831	STK11	T155	T150K	150	Missense	distal	-5	no	17.567	16.190	EPSD	COSMIC	16.403	Loss
CAMK_CAMKL_LKB_STK11_ST	P04637	TP53	Q15831	STK11	T155	P153H	153	Missense	proximal	-2	no	17.567	15.692	EPSD	COSMIC	16.403	Loss
CAMK_CAMKL_LKB_STK11_ST	P04637	TP53	Q15831	STK11	T155	A161F	161	Missense	distal	6	no	17.567	15.734	EPSD	COSMIC	16.403	Loss
CAMK_CAMKL_LKB_STK11_ST	P04637	TP53	Q15831	STK11	T155	V157E	157	Missense	proximal	2	no	17.567	17.131	EPSD	COSMIC	16.403	Down-regulation
CAMK_CAMKL_LKB_STK11_ST	P04637	TP53	Q15831	STK11	T155	D148H	148	Missense	distal	-7	no	17.567	16.813	EPSD	COSMIC	16.403	Down-regulation
CAMK_CAMKL_LKB_STK11_ST	P04637	TP53	Q15831	STK11	T155	M160T	160	Missense	distal	5	no	17.567	17.416	EPSD	COSMIC	16.403	Down-regulation
CAMK_CAMKL_LKB_STK11_ST	P04637	TP53	Q15831	STK11	T155	P153A	153	Missense	proximal	-2	no	17.567	16.666	EPSD	COSMIC	16.403	Down-regulation
CAMK_CAMKL_LKB_STK11_ST	P04637	TP53	Q15831	STK11	T155	T150R	150	Missense	distal	-5	no	17.567	16.276	EPSD	COSMIC	16.403	Loss
CAMK_CAMKL_LKB_STK11_ST	P04637	TP53	Q15831	STK11	T155	T155L	155	Missense	central	0	yes	17.567	0.000	EPSD	COSMIC	16.403	Loss
CAMK_CAMKL_LKB_STK11_ST	P04637	TP53	Q15831	STK11	T155	G154A	154	Missense	proximal	-1	no	17.567	17.748	EPSD	COSMIC	16.403	Up-regulation
CAMK_CAMKL_LKB_STK11_ST	P04637	TP53	Q15831	STK11	T155	T150A	150	Missense	distal	-5	no	17.567	15.942	EPSD	COSMIC	16.403	Loss
CAMK_CAMKL_LKB_STK11_ST	P04637	TP53	Q15831	STK11	T155	R158F	158	Missense	distal	3	no	17.567	19.592	EPSD	COSMIC	16.403	Up-regulation
CAMK_CAMKL_LKB_STK11_ST	P04637	TP53	Q15831	STK11	T155	P153F	153	Missense	proximal	-2	no	17.567	15.402	EPSD	COSMIC	16.403	Loss
CAMK_CAMKL_LKB_STK11_ST	P04637	TP53	Q15831	STK11	T155	D148Y	148	Missense	distal	-7	no	17.567	16.458	EPSD	COSMIC	16.403	Down-regulation
CAMK_CAMKL_LKB_STK11_ST	P04637	TP53	Q15831	STK11	T155	A161N	161	Missense	distal	6	no	17.567	18.308	EPSD	COSMIC	16.403	Up-regulation
CAMK_CAMKL_LKB_STK11_ST	P04637	TP53	Q15831	STK11	T155	G154R	154	Missense	proximal	-1	no	17.567	17.955	EPSD	COSMIC	16.403	Up-regulation
CAMK_CAMKL_LKB_STK11_ST	P04637	TP53	Q15831	STK11	T387	G389E	389	Missense	proximal	2	no	13.208	17.092	EPSD	COSMIC	16.403	Gain
CAMK_CAMKL_LKB_STK11_ST	P04637	TP53	Q15831	STK11	T387	G389V	389	Missense	proximal	2	no	13.208	17.527	EPSD	COSMIC	16.403	Gain
CAMK_CAMKL_LKB_STK11_ST	P04637	TP53	Q15831	STK11	S392	P390L	390	Missense	proximal	-2	no	12.302	16.690	PhosphoSitePlus;EPSD	COSMIC	16.403	Gain
CAMK_CAMKL_LKB_STK11_ST	P46937	YAP1	Q15831	STK11	T143	G140W	140	Missense	distal	-3	no	30.334	30.269	EPSD	COSMIC	16.403	Down-regulation
CAMK_CAMKL_LKB_STK11_ST	P46937	YAP1	Q15831	STK11	T143	T145S	145	Missense	proximal	2	no	30.334	29.816	EPSD	COSMIC	16.403	Down-regulation
CAMK_CAMKL_LKB_STK11_ST	P46937	YAP1	Q15831	STK11	T143	P139F	139	Missense	distal	-4	no	30.334	30.147	EPSD	COSMIC	16.403	Down-regulation
CAMK_CAMKL_LKB_STK11_ST	P46937	YAP1	Q15831	STK11	S163	I167T	167	Missense	distal	4	no	16.377	16.638	EPSD	COSMIC	16.403	Gain
CAMK_CAMKL_LKB_STK11_ST	P46937	YAP1	Q15831	STK11	S163	E166G	166	Missense	distal	3	no	16.377	20.386	EPSD	COSMIC	16.403	Gain
CAMK_CAMKL_LKB_STK11_ST	P46937	YAP1	Q15831	STK11	S350	L352P	352	Missense	proximal	2	no	28.145	31.666	EPSD	COSMIC	16.403	Up-regulation
CAMK_CAMKL_LKB_STK11_ST	P46937	YAP1	Q15831	STK11	S350	L348P	348	Missense	proximal	-2	no	28.145	23.757	EPSD	COSMIC	16.403	Down-regulation
CAMK_CAMKL_LKB_STK11_ST	P46937	YAP1	Q15831	STK11	T398	D399G	399	Missense	proximal	1	no	22.358	22.326	EPSD	COSMIC	16.403	Down-regulation
CAMK_CAMKL_LKB_STK11_ST	P46937	YAP1	Q15831	STK11	T398	E396K	396	Missense	proximal	-2	no	22.358	24.943	EPSD	COSMIC	16.403	Up-regulation
CAMK_CAMKL_LKB_STK11_ST	P46937	YAP1	Q15831	STK11	T398	D399H	399	Missense	proximal	1	no	22.358	22.330	EPSD	COSMIC	16.403	Down-regulation
CAMK_CAMKL_LKB_STK11_ST	P46937	YAP1	Q15831	STK11	T398	D395G	395	Missense	distal	-3	no	22.358	22.191	EPSD	COSMIC	16.403	Down-regulation
CAMK_CAMKL_LKB_STK11_ST	P46937	YAP1	Q15831	STK11	T412	N418T	418	Missense	distal	6	no	19.292	18.855	EPSD	COSMIC	16.403	Down-regulation
CAMK_CAMKL_LKB_STK11_ST	P46937	YAP1	Q15831	STK11	T412	F416L	416	Missense	distal	4	no	19.292	19.489	EPSD	COSMIC	16.403	Up-regulation
CAMK_CAMKL_LKB_STK11_ST	P46937	YAP1	Q15831	STK11	T412	R411Q	411	Missense	proximal	-1	no	19.292	19.355	EPSD	COSMIC	16.403	Up-regulation
CAMK_CAMKL_LKB_STK11_ST	P46937	YAP1	Q15831	STK11	T425	D427H	427	Missense	proximal	2	no	27.793	22.049	EPSD	COSMIC	16.403	Down-regulation
CAMK_CAMKL_LKB_STK11_ST	P46937	YAP1	Q15831	STK11	T425	N418T	418	Missense	distal	-7	no	27.793	28.582	EPSD	COSMIC	16.403	Up-regulation
CAMK_CAMKL_LKB_STK11_ST	P46937	YAP1	Q15831	STK11	T425	S432C	432	Missense	distal	7	no	27.793	28.389	EPSD	COSMIC	16.403	Up-regulation
CAMK_CAMKL_LKB_STK11_ST	P46937	YAP1	Q15831	STK11	T425	I429L	429	Missense	distal	4	no	27.793	27.660	EPSD	COSMIC	16.403	Down-regulation
CAMK_CAMKL_LKB_STK11_ST	Q9H0K1	SIK2	Q15831	STK11	T175	P180F	180	Missense	distal	5	no	60.719	58.896	PhosphoSitePlus	COSMIC	16.403	Down-regulation
CAMK_CAMKL_LKB_STK11_ST	Q7KZI7	MARK2	Q15831	STK11	T201	G195E	195	Missense	distal	-6	no	21.453	21.442	EPSD	COSMIC	16.403	Down-regulation
CAMK_CAMKL_LKB_STK11_ST	Q7KZI7	MARK2	Q15831	STK11	T201	T201P	201	Missense	central	0	yes	21.453	0.000	EPSD	COSMIC	16.403	Loss
CAMK_CAMKL_LKB_STK11_ST	Q7KZI7	MARK2	Q15831	STK11	T201	S197N	197	Missense	distal	-4	no	21.453	21.968	EPSD	COSMIC	16.403	Up-regulation
CAMK_CAMKL_LKB_STK11_ST	Q7KZI7	MARK2	Q15831	STK11	T208	T201P	201	Missense	distal	-7	no	62.070	60.704	PhosphoSitePlus	COSMIC	16.403	Down-regulation
CAMK_CAMKL_LKB_STK11_ST	Q7KZI7	MARK2	Q15831	STK11	T208	P213S	213	Missense	distal	5	no	62.070	61.608	PhosphoSitePlus	COSMIC	16.403	Down-regulation
CAMK_CAMKL_LKB_STK11_ST	Q7KZI7	MARK2	Q15831	STK11	S212	P213S	213	Missense	proximal	1	no	22.455	22.476	EPSD	COSMIC	16.403	Up-regulation
CAMK_CAMKL_LKB_STK11_ST	Q7KZI7	MARK2	Q15831	STK11	S212	A216D	216	Missense	distal	4	no	22.455	22.733	EPSD	COSMIC	16.403	Up-regulation
CAMK_CAMKL_LKB_STK11_ST	Q7KZI7	MARK2	Q15831	STK11	T467	E462D	462	Missense	distal	-5	no	16.142	16.868	EPSD	COSMIC	16.403	Gain
CAMK_CAMKL_LKB_STK11_ST	Q7KZI7	MARK2	Q15831	STK11	S571	P570H	570	Missense	proximal	-1	no	21.105	21.551	EPSD	COSMIC	16.403	Up-regulation
CAMK_CAMKL_LKB_STK11_ST	Q7KZI7	MARK2	Q15831	STK11	S571	R564H	564	Missense	distal	-7	no	21.105	21.682	EPSD	COSMIC	16.403	Up-regulation
CAMK_CAMKL_LKB_STK11_ST	Q7KZI7	MARK2	Q15831	STK11	S571	P566L	566	Missense	distal	-5	no	21.105	18.563	EPSD	COSMIC	16.403	Down-regulation
CAMK_CAMKL_LKB_STK11_ST	Q7KZI7	MARK2	Q15831	STK11	S571	S569F	569	Missense	proximal	-2	no	21.105	18.382	EPSD	COSMIC	16.403	Down-regulation
CAMK_CAMKL_LKB_STK11_ST	Q7KZI7	MARK2	Q15831	STK11	S571	P570T	570	Missense	proximal	-1	no	21.105	21.112	EPSD	COSMIC	16.403	Up-regulation
CAMK_CAMKL_LKB_STK11_ST	Q7KZI7	MARK2	Q15831	STK11	S759	R757Q	757	Missense	proximal	-2	no	19.465	18.310	EPSD	COSMIC	16.403	Down-regulation
CAMK_CAMKL_LKB_STK11_ST	Q7KZI7	MARK2	Q15831	STK11	S759	S759L	759	Missense	central	0	yes	19.465	0.000	EPSD	COSMIC	16.403	Loss
CAMK_CAMKL_LKB_STK11_ST	Q7KZI7	MARK2	Q15831	STK11	S759	L755Q	755	Missense	distal	-4	no	19.465	19.624	EPSD	COSMIC	16.403	Up-regulation
CAMK_CAMKL_LKB_STK11_ST	Q7KZI7	MARK2	Q15831	STK11	S759	C753Y	753	Missense	distal	-6	no	19.465	19.499	EPSD	COSMIC	16.403	Up-regulation
CAMK_CAMKL_LKB_STK11_ST	Q7KZI7	MARK2	Q15831	STK11	S759	S759F	759	Missense	central	0	yes	19.465	0.000	EPSD	COSMIC	16.403	Loss
CAMK_CAMKL_LKB_STK11_ST	Q7KZI7	MARK2	Q15831	STK11	S759	R757W	757	Missense	proximal	-2	no	19.465	17.449	EPSD	COSMIC	16.403	Down-regulation
CAMK_CAMKL_LKB_STK11_ST	Q7KZI7	MARK2	Q15831	STK11	S759	G762R	762	Missense	distal	3	no	19.465	12.979	EPSD	COSMIC	16.403	Loss
CAMK_CAMKL_LKB_STK11_ST	Q9NRH2	SNRK	Q15831	STK11	T173	T172P	172	Missense	proximal	-1	no	41.986	41.979	PhosphoSitePlus	COSMIC	16.403	Down-regulation
CAMK_CAMKL_LKB_STK11_ST	Q9NRH2	SNRK	Q15831	STK11	T173	T172M	172	Missense	proximal	-1	no	41.986	42.641	PhosphoSitePlus	COSMIC	16.403	Up-regulation
CAMK_CAMKL_LKB_STK11_ST	Q9NRH2	SNRK	Q15831	STK11	T543	S541L	541	Missense	proximal	-2	no	14.905	18.735	EPSD	COSMIC	16.403	Gain
CAMK_CAMK2_CAMK2D_ST	P55327	TPD52	Q13557-8	CAMK2D	T64	E59K	59	Missense	distal	-5	no	45.209	44.033	EPSD	COSMIC	37.605	Down-regulation
CAMK_CAMKL_MARK_MARK1_ST	P10636	MAPT	Q9P0L2	MARK1	S228	S227N	227	Missense	proximal	-1	no	0.334	0.348	EPSD	COSMIC	0.230	Up-regulation
CAMK_CAMKL_MARK_MARK1_ST	P10636	MAPT	Q9P0L2	MARK1	S228	S227I	227	Missense	proximal	-1	no	0.334	0.346	EPSD	COSMIC	0.230	Up-regulation
CAMK_CAMKL_MARK_MARK1_ST	P10636	MAPT	Q9P0L2	MARK1	S228	E226K	226	Missense	proximal	-2	no	0.334	0.336	EPSD	COSMIC	0.230	Up-regulation
CAMK_CAMKL_MARK_MARK1_ST	P10636	MAPT	Q9P0L2	MARK1	S228	Q230R	230	Missense	proximal	2	no	0.334	0.328	EPSD	COSMIC	0.230	Down-regulation
CAMK_CAMKL_MARK_MARK1_ST	P10636	MAPT	Q9P0L2	MARK1	S228	P233S	233	Missense	distal	5	no	0.334	0.335	EPSD	COSMIC	0.230	Up-regulation
CAMK_CAMKL_MARK_MARK1_ST	P10636	MAPT	Q9P0L2	MARK1	S228	D225E	225	Missense	distal	-3	no	0.334	0.330	EPSD	COSMIC	0.230	Down-regulation
CAMK_CAMKL_MARK_MARK1_ST	P10636	MAPT	Q9P0L2	MARK1	S228	S227G	227	Missense	proximal	-1	no	0.334	0.354	EPSD	COSMIC	0.230	Up-regulation
CAMK_CAMKL_MARK_MARK1_ST	P10636	MAPT	Q9P0L2	MARK1	S228	S235L	235	Missense	distal	7	no	0.334	0.335	EPSD	COSMIC	0.230	Up-regulation
CAMK_CAMKL_MARK_MARK1_ST	P10636	MAPT	Q9P0L2	MARK1	S382	T386I	386	Missense	distal	4	no	0.139	0.256	EPSD	COSMIC	0.230	Gain
CAMK_CAMKL_MARK_MARK1_ST	P10636	MAPT	Q9P0L2	MARK1	S388	G385V	385	Missense	distal	-3	no	0.258	0.246	EPSD	COSMIC	0.230	Down-regulation
CAMK_CAMKL_MARK_MARK1_ST	P10636	MAPT	Q9P0L2	MARK1	S388	T386I	386	Missense	proximal	-2	no	0.258	0.315	EPSD	COSMIC	0.230	Up-regulation
CAMK_CAMKL_MARK_MARK1_ST	P10636	MAPT	Q9P0L2	MARK1	S447	S443Y	443	Missense	distal	-4	no	0.378	0.328	EPSD	COSMIC	0.230	Down-regulation
CAMK_CAMKL_MARK_MARK1_ST	P10636	MAPT	Q9P0L2	MARK1	S447	S447P	447	Missense	central	0	yes	0.378	0.000	EPSD	COSMIC	0.230	Loss
CAMK_CAMKL_MARK_MARK1_ST	P10636	MAPT	Q9P0L2	MARK1	S447	R448Q	448	Missense	proximal	1	no	0.378	0.379	EPSD	COSMIC	0.230	Up-regulation
CAMK_CAMKL_MARK_MARK1_ST	P10636	MAPT	Q9P0L2	MARK1	S512	P506S	506	Missense	distal	-6	no	0.259	0.219	EPSD	COSMIC	0.230	Loss
CAMK_CAMKL_MARK_MARK1_ST	P10636	MAPT	Q9P0L2	MARK1	S512	G518V	518	Missense	distal	6	no	0.259	0.242	EPSD	COSMIC	0.230	Down-regulation
CAMK_CAMKL_MARK_MARK1_ST	P10636	MAPT	Q9P0L2	MARK1	S512	R511C	511	Missense	proximal	-1	no	0.259	0.248	EPSD	COSMIC;CCLE	0.230	Down-regulation
CAMK_CAMKL_MARK_MARK1_ST	P10636	MAPT	Q9P0L2	MARK1	S512	G509V	509	Missense	distal	-3	no	0.259	0.248	EPSD	COSMIC	0.230	Down-regulation
CAMK_CAMKL_MARK_MARK1_ST	P10636	MAPT	Q9P0L2	MARK1	S512	P506L	506	Missense	distal	-6	no	0.259	0.231	EPSD	COSMIC	0.230	Down-regulation
CAMK_CAMKL_MARK_MARK1_ST	P10636	MAPT	Q9P0L2	MARK1	S527	G521V	521	Missense	distal	-6	no	0.291	0.294	EPSD	COSMIC	0.230	Up-regulation
CAMK_CAMKL_MARK_MARK1_ST	P10636	MAPT	Q9P0L2	MARK1	S527	R526H	526	Missense	proximal	-1	no	0.291	0.284	EPSD	COSMIC	0.230	Down-regulation
CAMK_CAMKL_MARK_MARK1_ST	P10636	MAPT	Q9P0L2	MARK1	S527	R528S	528	Missense	proximal	1	no	0.291	0.290	EPSD	COSMIC	0.230	Down-regulation
CAMK_CAMKL_MARK_MARK1_ST	P10636	MAPT	Q9P0L2	MARK1	S527	P530S	530	Missense	distal	3	no	0.291	0.305	EPSD	COSMIC	0.230	Up-regulation
CAMK_CAMKL_MARK_MARK1_ST	P10636	MAPT	Q9P0L2	MARK1	T529	R528S	528	Missense	proximal	-1	no	0.238	0.216	EPSD	COSMIC	0.230	Loss
CAMK_CAMKL_MARK_MARK1_ST	P10636	MAPT	Q9P0L2	MARK1	T529	P530S	530	Missense	proximal	1	no	0.238	0.227	EPSD	COSMIC	0.230	Loss
CAMK_CAMKL_MARK_MARK1_ST	P10636	MAPT	Q9P0L2	MARK1	T529	P535Q	535	Missense	distal	6	no	0.238	0.225	EPSD	COSMIC	0.230	Loss
CAMK_CAMKL_MARK_MARK1_ST	P10636	MAPT	Q9P0L2	MARK1	S531	R526H	526	Missense	distal	-5	no	0.313	0.311	EPSD	COSMIC	0.230	Down-regulation
CAMK_CAMKL_MARK_MARK1_ST	P10636	MAPT	Q9P0L2	MARK1	S531	R528S	528	Missense	distal	-3	no	0.313	0.309	EPSD	COSMIC	0.230	Down-regulation
CAMK_CAMKL_MARK_MARK1_ST	P10636	MAPT	Q9P0L2	MARK1	S531	P530S	530	Missense	proximal	-1	no	0.313	0.316	EPSD	COSMIC	0.230	Up-regulation
CAMK_CAMKL_MARK_MARK1_ST	P10636	MAPT	Q9P0L2	MARK1	S531	P536H	536	Missense	distal	5	no	0.313	0.316	EPSD	COSMIC	0.230	Up-regulation
CAMK_CAMKL_MARK_MARK1_ST	P10636	MAPT	Q9P0L2	MARK1	S531	P535Q	535	Missense	distal	4	no	0.313	0.309	EPSD	COSMIC	0.230	Down-regulation
CAMK_CAMKL_MARK_MARK1_ST	P10636	MAPT	Q9P0L2	MARK1	T548	P550S	550	Missense	proximal	2	no	0.437	0.433	EPSD	COSMIC	0.230	Down-regulation
CAMK_CAMKL_MARK_MARK1_ST	P10636	MAPT	Q9P0L2	MARK1	T548	P553R	553	Missense	distal	5	no	0.437	0.410	EPSD	COSMIC	0.230	Down-regulation
CAMK_CAMKL_MARK_MARK1_ST	P10636	MAPT	Q9P0L2	MARK1	T548	P553L	553	Missense	distal	5	no	0.437	0.447	EPSD	COSMIC	0.230	Up-regulation
CAMK_CAMKL_MARK_MARK1_ST	P10636	MAPT	Q9P0L2	MARK1	T548	S555F	555	Missense	distal	7	no	0.437	0.444	EPSD	COSMIC	0.230	Up-regulation
CAMK_CAMKL_MARK_MARK1_ST	P10636	MAPT	Q9P0L2	MARK1	T548	P553Q	553	Missense	distal	5	no	0.437	0.411	EPSD	COSMIC	0.230	Down-regulation
CAMK_CAMKL_MARK_MARK1_ST	P10636	MAPT	Q9P0L2	MARK1	S552	P550S	550	Missense	proximal	-2	no	0.211	0.264	EPSD	COSMIC	0.230	Gain
CAMK_CAMKL_MARK_MARK1_ST	P10636	MAPT	Q9P0L2	MARK1	S558	V565M	565	Missense	distal	7	no	0.264	0.262	EPSD	COSMIC	0.230	Down-regulation
CAMK_CAMKL_MARK_MARK1_ST	P10636	MAPT	Q9P0L2	MARK1	S558	R559C	559	Missense	proximal	1	no	0.264	0.272	EPSD	COSMIC	0.230	Up-regulation
CAMK_CAMKL_MARK_MARK1_ST	P10636	MAPT	Q9P0L2	MARK1	S558	P553R	553	Missense	distal	-5	no	0.264	0.268	EPSD	COSMIC	0.230	Up-regulation
CAMK_CAMKL_MARK_MARK1_ST	P10636	MAPT	Q9P0L2	MARK1	S558	P553L	553	Missense	distal	-5	no	0.264	0.273	EPSD	COSMIC	0.230	Up-regulation
CAMK_CAMKL_MARK_MARK1_ST	P10636	MAPT	Q9P0L2	MARK1	S558	S555F	555	Missense	distal	-3	no	0.264	0.257	EPSD	COSMIC	0.230	Down-regulation
CAMK_CAMKL_MARK_MARK1_ST	P10636	MAPT	Q9P0L2	MARK1	S558	P553Q	553	Missense	distal	-5	no	0.264	0.268	EPSD	COSMIC	0.230	Up-regulation
CAMK_CAMKL_MARK_MARK1_ST	P10636	MAPT	Q9P0L2	MARK1	S575	T580N	580	Missense	distal	5	no	0.346	0.328	EPSD	COSMIC	0.230	Down-regulation
CAMK_CAMKL_MARK_MARK1_ST	P10636	MAPT	Q9P0L2	MARK1	S575	G578S	578	Missense	distal	3	no	0.346	0.341	EPSD	COSMIC	0.230	Down-regulation
CAMK_CAMKL_MARK_MARK1_ST	P10636	MAPT	Q9P0L2	MARK1	S575	K571E	571	Missense	distal	-4	no	0.346	0.331	EPSD	COSMIC	0.230	Down-regulation
CAMK_CAMKL_MARK_MARK1_ST	P10636	MAPT	Q9P0L2	MARK1	S575	P568S	568	Missense	distal	-7	no	0.346	0.355	EPSD	COSMIC	0.230	Up-regulation
CAMK_CAMKL_MARK_MARK1_ST	P10636	MAPT	Q9P0L2	MARK1	S579	T580N	580	Missense	proximal	1	no	0.613	0.610	EPSD	COSMIC	0.230	Down-regulation
CAMK_CAMKL_MARK_MARK1_ST	P10636	MAPT	Q9P0L2	MARK1	S579	G578S	578	Missense	proximal	-1	no	0.613	0.593	EPSD	COSMIC	0.230	Down-regulation
CAMK_CAMKL_MARK_MARK1_ST	P10636	MAPT	Q9P0L2	MARK1	S602	S602G	602	Missense	central	0	yes	0.266	0.000	EPSD	COSMIC	0.230	Loss
CAMK_CAMKL_MARK_MARK1_ST	P10636	MAPT	Q9P0L2	MARK1	S602	I595L	595	Missense	distal	-7	no	0.266	0.259	EPSD	COSMIC	0.230	Down-regulation
CAMK_CAMKL_MARK_MARK1_ST	P10636	MAPT	Q9P0L2	MARK1	S602	K598T	598	Missense	distal	-4	no	0.266	0.251	EPSD	COSMIC	0.230	Down-regulation
CAMK_CAMKL_MARK_MARK1_ST	P10636	MAPT	Q9P0L2	MARK1	S602	C608W	608	Missense	distal	6	no	0.266	0.268	EPSD	COSMIC	0.230	Up-regulation
CAMK_CAMKL_MARK_MARK1_ST	P10636	MAPT	Q9P0L2	MARK1	S602	D600E	600	Missense	proximal	-2	no	0.266	0.228	EPSD	COSMIC	0.230	Loss
CAMK_CAMKL_MARK_MARK1_ST	P10636	MAPT	Q9P0L2	MARK1	S606	N613D	613	Missense	distal	7	no	0.330	0.331	EPSD	COSMIC	0.230	Up-regulation
CAMK_CAMKL_MARK_MARK1_ST	P10636	MAPT	Q9P0L2	MARK1	S606	S602G	602	Missense	distal	-4	no	0.330	0.266	EPSD	COSMIC	0.230	Down-regulation
CAMK_CAMKL_MARK_MARK1_ST	P10636	MAPT	Q9P0L2	MARK1	S606	C608W	608	Missense	proximal	2	no	0.330	0.327	EPSD	COSMIC	0.230	Down-regulation
CAMK_CAMKL_MARK_MARK1_ST	P10636	MAPT	Q9P0L2	MARK1	S606	S610L	610	Missense	distal	4	no	0.330	0.317	EPSD	COSMIC	0.230	Down-regulation
CAMK_CAMKL_MARK_MARK1_ST	P10636	MAPT	Q9P0L2	MARK1	S606	D600E	600	Missense	distal	-6	no	0.330	0.351	EPSD	COSMIC	0.230	Up-regulation
CAMK_CAMKL_MARK_MARK1_ST	P10636	MAPT	Q9P0L2	MARK1	S610	N613D	613	Missense	distal	3	no	0.595	0.600	EPSD	COSMIC	0.230	Up-regulation
CAMK_CAMKL_MARK_MARK1_ST	P10636	MAPT	Q9P0L2	MARK1	S610	C608W	608	Missense	proximal	-2	no	0.595	0.566	EPSD	COSMIC	0.230	Down-regulation
CAMK_CAMKL_MARK_MARK1_ST	P10636	MAPT	Q9P0L2	MARK1	S610	S610L	610	Missense	central	0	yes	0.595	0.000	EPSD	COSMIC	0.230	Loss
CAMK_CAMKL_MARK_MARK1_ST	P10636	MAPT	Q9P0L2	MARK1	S637	S633N	633	Missense	distal	-4	no	0.477	0.426	EPSD	COSMIC	0.230	Down-regulation
CAMK_CAMKL_MARK_MARK1_ST	P10636	MAPT	Q9P0L2	MARK1	S637	S633I	633	Missense	distal	-4	no	0.477	0.456	EPSD	COSMIC	0.230	Down-regulation
CAMK_CAMKL_MARK_MARK1_ST	P10636	MAPT	Q9P0L2	MARK1	S641	H647Y	647	Missense	distal	6	no	0.498	0.482	EPSD	COSMIC	0.230	Down-regulation
CAMK_CAMKL_MARK_MARK1_ST	P10636	MAPT	Q9P0L2	MARK1	S658	D662G	662	Missense	distal	4	no	0.256	0.238	EPSD	COSMIC	0.230	Down-regulation
CAMK_CAMKL_MARK_MARK1_ST	P10636	MAPT	Q9P0L2	MARK1	S658	K664N	664	Missense	distal	6	no	0.256	0.246	EPSD	COSMIC	0.230	Down-regulation
CAMK_CAMKL_MARK_MARK1_ST	P10636	MAPT	Q9P0L2	MARK1	S669	S669L	669	Missense	central	0	yes	0.283	0.000	EPSD	COSMIC	0.230	Loss
CAMK_CAMKL_MARK_MARK1_ST	P10636	MAPT	Q9P0L2	MARK1	S669	R666K	666	Missense	distal	-3	no	0.283	0.287	EPSD	COSMIC	0.230	Up-regulation
CAMK_CAMKL_MARK_MARK1_ST	P10636	MAPT	Q9P0L2	MARK1	S669	S673F	673	Missense	distal	4	no	0.283	0.178	EPSD	COSMIC	0.230	Loss
CAMK_CAMKL_MARK_MARK1_ST	P10636	MAPT	Q9P0L2	MARK1	S669	K670N	670	Missense	proximal	1	no	0.283	0.281	EPSD	COSMIC	0.230	Down-regulation
CAMK_CAMKL_MARK_MARK1_ST	P10636	MAPT	Q9P0L2	MARK1	S669	K664N	664	Missense	distal	-5	no	0.283	0.281	EPSD	COSMIC	0.230	Down-regulation
CAMK_CAMKL_MARK_MARK1_ST	P10636	MAPT	Q9P0L2	MARK1	S669	L674Q	674	Missense	distal	5	no	0.283	0.247	EPSD	COSMIC	0.230	Down-regulation
CAMK_CAMKL_MARK_MARK1_ST	P10636	MAPT	Q9P0L2	MARK1	S673	V680I	680	Missense	distal	7	no	0.588	0.584	EPSD	COSMIC	0.230	Down-regulation
CAMK_CAMKL_MARK_MARK1_ST	P10636	MAPT	Q9P0L2	MARK1	S673	S669L	669	Missense	distal	-4	no	0.588	0.551	EPSD	COSMIC	0.230	Down-regulation
CAMK_CAMKL_MARK_MARK1_ST	P10636	MAPT	Q9P0L2	MARK1	S673	R666K	666	Missense	distal	-7	no	0.588	0.587	EPSD	COSMIC	0.230	Down-regulation
CAMK_CAMKL_MARK_MARK1_ST	P10636	MAPT	Q9P0L2	MARK1	S673	S673F	673	Missense	central	0	yes	0.588	0.000	EPSD	COSMIC	0.230	Loss
CAMK_CAMKL_MARK_MARK1_ST	P10636	MAPT	Q9P0L2	MARK1	S673	K670N	670	Missense	distal	-3	no	0.588	0.577	EPSD	COSMIC	0.230	Down-regulation
CAMK_CAMKL_MARK_MARK1_ST	P10636	MAPT	Q9P0L2	MARK1	S673	L674Q	674	Missense	proximal	1	no	0.588	0.578	EPSD	COSMIC	0.230	Down-regulation
CAMK_CAMKL_MARK_MARK1_ST	P10636	MAPT	Q9P0L2	MARK1	S713	E708D	708	Missense	distal	-5	no	0.470	0.471	EPSD	COSMIC	0.230	Up-regulation
CAMK_CAMKL_MARK_MARK1_ST	P10636	MAPT	Q9P0L2	MARK1	S713	G706R	706	Missense	distal	-7	no	0.470	0.461	EPSD	COSMIC	0.230	Down-regulation
CAMK_CAMKL_MARK_MARK1_ST	P10636	MAPT	Q9P0L2	MARK1	S713	V710M	710	Missense	distal	-3	no	0.470	0.474	EPSD	COSMIC	0.230	Up-regulation
CAMK_CAMKL_MARK_MARK1_ST	P10636	MAPT	Q9P0L2	MARK1	S713	E708K	708	Missense	distal	-5	no	0.470	0.471	EPSD	COSMIC	0.230	Up-regulation
CAMK_CAMKL_MARK_MARK1_ST	P10636	MAPT	Q9P0L2	MARK1	S713	V710A	710	Missense	distal	-3	no	0.470	0.475	EPSD	COSMIC	0.230	Up-regulation
CAMK_CAMKL_MARK_MARK1_ST	P10636	MAPT	Q9P0L2	MARK1	S726	G732S	732	Missense	distal	6	no	0.238	0.240	EPSD	COSMIC	0.230	Up-regulation
CAMK_CAMKL_MARK_MARK1_ST	P10636	MAPT	Q9P0L2	MARK1	S726	G732C	732	Missense	distal	6	no	0.238	0.230	EPSD	COSMIC	0.230	Down-regulation
CAMK_CAMKL_MARK_MARK1_ST	P10636	MAPT	Q9P0L2	MARK1	S726	R723W	723	Missense	distal	-3	no	0.238	0.234	EPSD	COSMIC	0.230	Down-regulation
CAMK_CAMKL_MARK_MARK1_ST	P10636	MAPT	Q9P0L2	MARK1	S726	V728M	728	Missense	proximal	2	no	0.238	0.230	EPSD	COSMIC	0.230	Down-regulation
CAMK_CAMKL_MARK_MARK1_ST	P10636	MAPT	Q9P0L2	MARK1	S726	V728A	728	Missense	proximal	2	no	0.238	0.229	EPSD	COSMIC	0.230	Loss
CAMK_CAMKL_MARK_MARK1_ST	P10636	MAPT	Q9P0L2	MARK1	S730	D735N	735	Missense	distal	5	no	0.203	0.239	EPSD	COSMIC	0.230	Gain
CAMK_CAMKL_MARK_MARK1_ST	P10636	MAPT	Q9P0L2	MARK1	S739	G732S	732	Missense	distal	-7	no	0.354	0.346	EPSD	COSMIC	0.230	Down-regulation
CAMK_CAMKL_MARK_MARK1_ST	P10636	MAPT	Q9P0L2	MARK1	S739	D735N	735	Missense	distal	-4	no	0.354	0.348	EPSD	COSMIC	0.230	Down-regulation
CAMK_CAMKL_MARK_MARK1_ST	P10636	MAPT	Q9P0L2	MARK1	S739	G732C	732	Missense	distal	-7	no	0.354	0.338	EPSD	COSMIC	0.230	Down-regulation
CAMK_CAMKL_MARK_MARK1_ST	P10636	MAPT	Q9P0L2	MARK1	S739	T744M	744	Missense	distal	5	no	0.354	0.342	EPSD	COSMIC	0.230	Down-regulation
CAMK_CAMKL_MARK_MARK1_ST	P10636	MAPT	Q9P0L2	MARK1	S739	A743T	743	Missense	distal	4	no	0.354	0.263	EPSD	COSMIC	0.230	Down-regulation
CAMK_CAMKL_MARK_MARK1_ST	Q155Q3	DIXDC1	Q9P0L2	MARK1	S94	A93S	93	Missense	proximal	-1	no	0.257	0.246	EPSD	COSMIC	0.230	Down-regulation
CAMK_CAMKL_MARK_MARK1_ST	Q155Q3	DIXDC1	Q9P0L2	MARK1	S228	A229T	229	Missense	proximal	1	no	0.254	0.266	EPSD	COSMIC	0.230	Up-regulation
CAMK_CAMKL_MARK_MARK1_ST	Q155Q3	DIXDC1	Q9P0L2	MARK1	S228	S231I	231	Missense	distal	3	no	0.254	0.249	EPSD	COSMIC	0.230	Down-regulation
CAMK_CAMKL_MARK_MARK1_ST	Q155Q3	DIXDC1	Q9P0L2	MARK1	S238	E240Q	240	Missense	proximal	2	no	0.253	0.254	EPSD	COSMIC	0.230	Up-regulation
CAMK_CAMKL_MARK_MARK1_ST	Q155Q3	DIXDC1	Q9P0L2	MARK1	S238	Q237K	237	Missense	proximal	-1	no	0.253	0.273	EPSD	COSMIC	0.230	Up-regulation
CAMK_CAMKL_MARK_MARK1_ST	Q155Q3	DIXDC1	Q9P0L2	MARK1	S238	A242V	242	Missense	distal	4	no	0.253	0.258	EPSD	COSMIC	0.230	Up-regulation
CAMK_CAMKL_MARK_MARK1_ST	Q155Q3	DIXDC1	Q9P0L2	MARK1	S238	S231I	231	Missense	distal	-7	no	0.253	0.246	EPSD	COSMIC	0.230	Down-regulation
CAMK_CAMKL_MARK_MARK1_ST	Q155Q3	DIXDC1	Q9P0L2	MARK1	S522	L515H	515	Missense	distal	-7	no	0.233	0.247	EPSD	COSMIC	0.230	Up-regulation
CAMK_CAMKL_MARK_MARK1_ST	Q155Q3	DIXDC1	Q9P0L2	MARK1	S592	L587V	587	Missense	distal	-5	no	0.505	0.504	EPSD;PhosphoSitePlus	COSMIC	0.230	Down-regulation
CAMK_CAMKL_MARK_MARK1_ST	Q155Q3	DIXDC1	Q9P0L2	MARK1	S592	P594A	594	Missense	proximal	2	no	0.505	0.500	EPSD;PhosphoSitePlus	COSMIC	0.230	Down-regulation
CAMK_CAMKL_MARK_MARK1_ST	Q155Q3	DIXDC1	Q9P0L2	MARK1	S592	T599I	599	Missense	distal	7	no	0.505	0.506	EPSD;PhosphoSitePlus	COSMIC	0.230	Up-regulation
CAMK_CAMKL_MARK_MARK1_ST	Q99689	FEZ1	Q9P0L2	MARK1	S247	Q253H	253	Missense	distal	6	no	0.229	0.239	EPSD	COSMIC	0.230	Gain
CAMK_CAMKL_MARK_MARK1_ST	Q99689	FEZ1	Q9P0L2	MARK1	S316	G319S	319	Missense	distal	3	no	0.301	0.295	EPSD	COSMIC	0.230	Down-regulation
AGC_GRK_GRK_GRK7_ST	Q16625	OCLN	Q8WTQ7	GRK7	S3	R4W	4	Missense	proximal	1	no	1.539	1.543	EPSD	COSMIC	1.098	Up-regulation
Other_ULK_ULK_ULK3_ST	Q6PHR2	ULK3	Q6PHR2	ULK3	S147	P151S	151	Missense	distal	4	no	1.272	1.675	EPSD	COSMIC	1.534	Gain
Other_ULK_ULK_ULK3_ST	Q6PHR2	ULK3	Q6PHR2	ULK3	S300	G298W	298	Missense	proximal	-2	no	5.133	5.131	PhosphoSitePlus;EPSD	COSMIC	1.534	Down-regulation
Other_ULK_ULK_ULK3_ST	Q6PHR2	ULK3	Q6PHR2	ULK3	S350	V348I	348	Missense	proximal	-2	no	4.739	4.732	EPSD;PhosphoSitePlus	COSMIC	1.534	Down-regulation
Other_ULK_ULK_ULK3_ST	Q6PHR2	ULK3	Q6PHR2	ULK3	S350	N352D	352	Missense	proximal	2	no	4.739	4.703	EPSD;PhosphoSitePlus	COSMIC	1.534	Down-regulation
Other_ULK_ULK_ULK3_ST	Q6PHR2	ULK3	Q6PHR2	ULK3	S384	A385S	385	Missense	proximal	1	no	5.396	5.353	EPSD;PhosphoSitePlus	COSMIC	1.534	Down-regulation
Other_ULK_ULK_ULK3_ST	Q6PHR2	ULK3	Q6PHR2	ULK3	S464	V465G	465	Missense	proximal	1	no	4.079	3.978	EPSD;PhosphoSitePlus	COSMIC;GDSC;CCLE	1.534	Down-regulation
CAMK_CAMKL_MARK_MARK2_ST	Q8WUI4	HDAC7	Q7KZI7	MARK2	T153	P157L	157	Missense	distal	4	no	220.243	348.822	EPSD	COSMIC	271.430	Gain
CAMK_CAMKL_MARK_MARK2_ST	Q8WUI4	HDAC7	Q7KZI7	MARK2	S155	P149L	149	Missense	distal	-6	no	371.176	373.387	PhosphoSitePlus	COSMIC	271.430	Up-regulation
CAMK_CAMKL_MARK_MARK2_ST	Q8WUI4	HDAC7	Q7KZI7	MARK2	S155	P149T	149	Missense	distal	-6	no	371.176	372.101	PhosphoSitePlus	COSMIC	271.430	Up-regulation
CAMK_CAMKL_MARK_MARK2_ST	Q8WUI4	HDAC7	Q7KZI7	MARK2	S155	K160N	160	Missense	distal	5	no	371.176	370.761	PhosphoSitePlus	COSMIC	271.430	Down-regulation
CAMK_CAMKL_MARK_MARK2_ST	Q8WUI4	HDAC7	Q7KZI7	MARK2	S155	R162H	162	Missense	distal	7	no	371.176	362.181	PhosphoSitePlus	COSMIC	271.430	Down-regulation
CAMK_CAMKL_MARK_MARK2_ST	Q8WUI4	HDAC7	Q7KZI7	MARK2	S155	P157L	157	Missense	proximal	2	no	371.176	352.781	PhosphoSitePlus	COSMIC	271.430	Down-regulation
CAMK_CAMKL_MARK_MARK2_ST	Q8WUI4	HDAC7	Q7KZI7	MARK2	S181	S181N	181	Missense	central	0	yes	286.861	0.000	EPSD	COSMIC	271.430	Loss
CAMK_CAMKL_MARK_MARK2_ST	Q8WUI4	HDAC7	Q7KZI7	MARK2	S181	R187W	187	Missense	distal	6	no	286.861	274.084	EPSD	COSMIC	271.430	Down-regulation
CAMK_CAMKL_MARK_MARK2_ST	Q8WUI4	HDAC7	Q7KZI7	MARK2	S181	S181R	181	Missense	central	0	yes	286.861	0.000	EPSD	COSMIC	271.430	Loss
CAMK_CAMKL_MARK_MARK2_ST	Q8WUI4	HDAC7	Q7KZI7	MARK2	S181	K179E	179	Missense	proximal	-2	no	286.861	287.547	EPSD	COSMIC	271.430	Up-regulation
CAMK_CAMKL_MARK_MARK2_ST	Q8WUI4	HDAC7	Q7KZI7	MARK2	S181	R178Q	178	Missense	distal	-3	no	286.861	184.818	EPSD	COSMIC	271.430	Loss
CAMK_CAMKL_MARK_MARK2_ST	Q8WUI4	HDAC7	Q7KZI7	MARK2	S181	P184L	184	Missense	distal	3	no	286.861	287.491	EPSD	COSMIC	271.430	Up-regulation
CAMK_CAMKL_MARK_MARK2_ST	Q8WUI4	HDAC7	Q7KZI7	MARK2	S181	R188Q	188	Missense	distal	7	no	286.861	269.611	EPSD	COSMIC	271.430	Loss
CAMK_CAMKL_MARK_MARK2_ST	Q8WUI4	HDAC7	Q7KZI7	MARK2	S181	P175L	175	Missense	distal	-6	no	286.861	289.071	EPSD	COSMIC	271.430	Up-regulation
CAMK_CAMKL_MARK_MARK2_ST	Q8WUI4	HDAC7	Q7KZI7	MARK2	S181	L186R	186	Missense	distal	5	no	286.861	281.079	EPSD	COSMIC	271.430	Down-regulation
CAMK_CAMKL_MARK_MARK2_ST	Q8WUI4	HDAC7	Q7KZI7	MARK2	S345	E342K	342	Missense	distal	-3	no	201.928	314.452	EPSD	COSMIC	271.430	Gain
CAMK_CAMKL_MARK_MARK2_ST	Q8WUI4	HDAC7	Q7KZI7	MARK2	S534	S534F	534	Missense	central	0	yes	295.390	0.000	EPSD	COSMIC	271.430	Loss
CAMK_CAMKL_MARK_MARK2_ST	Q8WUI4	HDAC7	Q7KZI7	MARK2	S534	H531Y	531	Missense	distal	-3	no	295.390	288.642	EPSD	COSMIC	271.430	Down-regulation
CAMK_CAMKL_MARK_MARK2_ST	Q8WUI4	HDAC7	Q7KZI7	MARK2	S550	R554L	554	Missense	distal	4	no	217.080	275.310	EPSD	COSMIC;CCLE	271.430	Gain
CAMK_CAMKL_MARK_MARK2_ST	Q8WUI4	HDAC7	Q7KZI7	MARK2	S573	R570G	570	Missense	distal	-3	no	330.402	284.100	EPSD	COSMIC	271.430	Down-regulation
CAMK_CAMKL_MARK_MARK2_ST	Q8WUI4	HDAC7	Q7KZI7	MARK2	S573	R568G	568	Missense	distal	-5	no	330.402	332.266	EPSD	COSMIC	271.430	Up-regulation
CAMK_CAMKL_MARK_MARK2_ST	Q8WUI4	HDAC7	Q7KZI7	MARK2	S573	L567H	567	Missense	distal	-6	no	330.402	328.046	EPSD	COSMIC	271.430	Down-regulation
CAMK_CAMKL_MARK_MARK2_ST	Q8WUI4	HDAC7	Q7KZI7	MARK2	S595	G602R	602	Missense	distal	7	no	261.424	272.345	EPSD	COSMIC;CCLE	271.430	Gain
CAMK_CAMKL_MARK_MARK2_ST	P56524	HDAC4	Q7KZI7	MARK2	S5	L10F	10	Missense	distal	5	no	306.977	290.131	EPSD	COSMIC	271.430	Down-regulation
CAMK_CAMKL_MARK_MARK2_ST	P56524	HDAC4	Q7KZI7	MARK2	T223	G220R	220	Missense	distal	-3	no	233.963	280.264	EPSD	COSMIC;GDSC	271.430	Gain
CAMK_CAMKL_MARK_MARK2_ST	P56524	HDAC4	Q7KZI7	MARK2	S246	F239Y	239	Missense	distal	-7	no	407.942	407.897	PhosphoSitePlus	COSMIC	271.430	Down-regulation
CAMK_CAMKL_MARK_MARK2_ST	P56524	HDAC4	Q7KZI7	MARK2	S246	E247K	247	Missense	proximal	1	no	407.942	402.949	PhosphoSitePlus	COSMIC	271.430	Down-regulation
CAMK_CAMKL_MARK_MARK2_ST	P56524	HDAC4	Q7KZI7	MARK2	S246	P240S	240	Missense	distal	-6	no	407.942	408.600	PhosphoSitePlus	COSMIC	271.430	Up-regulation
CAMK_CAMKL_MARK_MARK2_ST	P56524	HDAC4	Q7KZI7	MARK2	S266	L268F	268	Missense	proximal	2	no	325.486	326.431	EPSD	COSMIC	271.430	Up-regulation
CAMK_CAMKL_MARK_MARK2_ST	P56524	HDAC4	Q7KZI7	MARK2	S266	R270L	270	Missense	distal	4	no	325.486	383.716	EPSD	COSMIC	271.430	Up-regulation
CAMK_CAMKL_MARK_MARK2_ST	P56524	HDAC4	Q7KZI7	MARK2	S266	K259R	259	Missense	distal	-7	no	325.486	325.425	EPSD	COSMIC	271.430	Down-regulation
CAMK_CAMKL_MARK_MARK2_ST	P56524	HDAC4	Q7KZI7	MARK2	S293	C292W	292	Missense	proximal	-1	no	292.315	267.183	EPSD	COSMIC	271.430	Loss
CAMK_CAMKL_MARK_MARK2_ST	P56524	HDAC4	Q7KZI7	MARK2	S293	S294G	294	Missense	proximal	1	no	292.315	288.862	EPSD	COSMIC	271.430	Down-regulation
CAMK_CAMKL_MARK_MARK2_ST	P56524	HDAC4	Q7KZI7	MARK2	S307	S311I	311	Missense	distal	4	no	256.724	318.171	EPSD	COSMIC	271.430	Gain
CAMK_CAMKL_MARK_MARK2_ST	P56524	HDAC4	Q7KZI7	MARK2	S311	S311I	311	Missense	central	0	yes	290.073	0.000	EPSD	COSMIC	271.430	Loss
CAMK_CAMKL_MARK_MARK2_ST	P56524	HDAC4	Q7KZI7	MARK2	S339	R336Q	336	Missense	distal	-3	no	319.764	217.722	EPSD	COSMIC	271.430	Loss
CAMK_CAMKL_MARK_MARK2_ST	P56524	HDAC4	Q7KZI7	MARK2	S339	L333P	333	Missense	distal	-6	no	319.764	317.554	EPSD	COSMIC;GDSC;CCLE	271.430	Down-regulation
CAMK_CAMKL_MARK_MARK2_ST	P56524	HDAC4	Q7KZI7	MARK2	S339	A341S	341	Missense	proximal	2	no	319.764	358.946	EPSD	COSMIC	271.430	Up-regulation
CAMK_CAMKL_MARK_MARK2_ST	P56524	HDAC4	Q7KZI7	MARK2	S339	P344L	344	Missense	distal	5	no	319.764	333.805	EPSD	COSMIC	271.430	Up-regulation
CAMK_CAMKL_MARK_MARK2_ST	P56524	HDAC4	Q7KZI7	MARK2	S339	Y346C	346	Missense	distal	7	no	319.764	319.974	EPSD	COSMIC	271.430	Up-regulation
CAMK_CAMKL_MARK_MARK2_ST	P56524	HDAC4	Q7KZI7	MARK2	S339	G338V	338	Missense	proximal	-1	no	319.764	301.822	EPSD	COSMIC	271.430	Down-regulation
CAMK_CAMKL_MARK_MARK2_ST	P56524	HDAC4	Q7KZI7	MARK2	S584	E587D	587	Missense	distal	3	no	303.735	339.262	EPSD	COSMIC	271.430	Up-regulation
CAMK_CAMKL_MARK_MARK2_ST	P56524	HDAC4	Q7KZI7	MARK2	S584	R581H	581	Missense	distal	-3	no	303.735	280.756	EPSD	COSMIC	271.430	Down-regulation
CAMK_CAMKL_MARK_MARK2_ST	P56524	HDAC4	Q7KZI7	MARK2	S584	S584I	584	Missense	central	0	yes	303.735	0.000	EPSD	COSMIC	271.430	Loss
CAMK_CAMKL_MARK_MARK2_ST	P56524	HDAC4	Q7KZI7	MARK2	S741	V747L	747	Missense	distal	6	no	266.738	281.193	EPSD	COSMIC	271.430	Gain
CAMK_CAMKL_MARK_MARK2_ST	Q8TEW0	PARD3	Q7KZI7	MARK2	S143	R142H	142	Missense	proximal	-1	no	266.855	271.977	EPSD	COSMIC	271.430	Gain
CAMK_CAMKL_MARK_MARK2_ST	Q8TEW0	PARD3	Q7KZI7	MARK2	S144	I149T	149	Missense	distal	5	no	396.547	396.608	EPSD;PhosphoSitePlus	COSMIC	271.430	Up-regulation
CAMK_CAMKL_MARK_MARK2_ST	Q8TEW0	PARD3	Q7KZI7	MARK2	S144	R142H	142	Missense	proximal	-2	no	396.547	396.316	EPSD;PhosphoSitePlus	COSMIC	271.430	Down-regulation
CAMK_CAMKL_MARK_MARK2_ST	Q8TEW0	PARD3	Q7KZI7	MARK2	S144	A147T	147	Missense	distal	3	no	396.547	386.726	EPSD;PhosphoSitePlus	COSMIC	271.430	Down-regulation
CAMK_CAMKL_MARK_MARK2_ST	Q8TEW0	PARD3	Q7KZI7	MARK2	S154	S158L	158	Missense	distal	4	no	256.263	341.798	EPSD	COSMIC	271.430	Gain
CAMK_CAMKL_MARK_MARK2_ST	Q8TEW0	PARD3	Q7KZI7	MARK2	S174	F179L	179	Missense	distal	5	no	283.019	299.865	EPSD	COSMIC	271.430	Up-regulation
CAMK_CAMKL_MARK_MARK2_ST	Q8TEW0	PARD3	Q7KZI7	MARK2	S174	G178R	178	Missense	distal	4	no	283.019	222.662	EPSD	COSMIC	271.430	Loss
CAMK_CAMKL_MARK_MARK2_ST	Q8TEW0	PARD3	Q7KZI7	MARK2	T175	F179L	179	Missense	distal	4	no	276.209	307.720	EPSD	COSMIC	271.430	Up-regulation
CAMK_CAMKL_MARK_MARK2_ST	Q8TEW0	PARD3	Q7KZI7	MARK2	T175	G178R	178	Missense	distal	3	no	276.209	294.021	EPSD	COSMIC	271.430	Up-regulation
CAMK_CAMKL_MARK_MARK2_ST	Q8TEW0	PARD3	Q7KZI7	MARK2	S201	R204W	204	Missense	distal	3	no	277.002	241.933	EPSD	COSMIC	271.430	Loss
CAMK_CAMKL_MARK_MARK2_ST	Q8TEW0	PARD3	Q7KZI7	MARK2	S201	P203L	203	Missense	proximal	2	no	277.002	258.607	EPSD	COSMIC;GDSC	271.430	Loss
CAMK_CAMKL_MARK_MARK2_ST	Q8TEW0	PARD3	Q7KZI7	MARK2	S201	K195E	195	Missense	distal	-6	no	277.002	276.179	EPSD	COSMIC	271.430	Down-regulation
CAMK_CAMKL_MARK_MARK2_ST	Q8TEW0	PARD3	Q7KZI7	MARK2	S225	V229G	229	Missense	distal	4	no	268.273	293.487	EPSD	COSMIC	271.430	Gain
CAMK_CAMKL_MARK_MARK2_ST	Q8TEW0	PARD3	Q7KZI7	MARK2	S225	M228I	228	Missense	distal	3	no	268.273	294.837	EPSD	COSMIC	271.430	Gain
CAMK_CAMKL_MARK_MARK2_ST	Q8TEW0	PARD3	Q7KZI7	MARK2	T298	R305C	305	Missense	distal	7	no	317.235	304.920	EPSD	COSMIC	271.430	Down-regulation
CAMK_CAMKL_MARK_MARK2_ST	Q8TEW0	PARD3	Q7KZI7	MARK2	T298	R305H	305	Missense	distal	7	no	317.235	308.239	EPSD	COSMIC	271.430	Down-regulation
CAMK_CAMKL_MARK_MARK2_ST	Q8TEW0	PARD3	Q7KZI7	MARK2	T298	G300R	300	Missense	proximal	2	no	317.235	323.684	EPSD	COSMIC	271.430	Up-regulation
CAMK_CAMKL_MARK_MARK2_ST	Q8TEW0	PARD3	Q7KZI7	MARK2	T298	T298P	298	Missense	central	0	yes	317.235	0.000	EPSD	COSMIC	271.430	Loss
CAMK_CAMKL_MARK_MARK2_ST	Q8TEW0	PARD3	Q7KZI7	MARK2	T298	T298I	298	Missense	central	0	yes	317.235	0.000	EPSD	COSMIC	271.430	Loss
CAMK_CAMKL_MARK_MARK2_ST	Q8TEW0	PARD3	Q7KZI7	MARK2	T298	R294Q	294	Missense	distal	-4	no	317.235	307.313	EPSD	COSMIC;GDSC;CCLE	271.430	Down-regulation
CAMK_CAMKL_MARK_MARK2_ST	Q8TEW0	PARD3	Q7KZI7	MARK2	S396	S393I	393	Missense	distal	-3	no	301.893	248.838	EPSD	COSMIC	271.430	Loss
CAMK_CAMKL_MARK_MARK2_ST	Q8TEW0	PARD3	Q7KZI7	MARK2	S396	G398E	398	Missense	proximal	2	no	301.893	310.034	EPSD	COSMIC	271.430	Up-regulation
CAMK_CAMKL_MARK_MARK2_ST	Q8TEW0	PARD3	Q7KZI7	MARK2	T446	V447L	447	Missense	proximal	1	no	295.550	286.462	EPSD	COSMIC	271.430	Down-regulation
CAMK_CAMKL_MARK_MARK2_ST	Q8TEW0	PARD3	Q7KZI7	MARK2	T453	L460I	460	Missense	distal	7	no	281.736	280.863	EPSD	COSMIC	271.430	Down-regulation
CAMK_CAMKL_MARK_MARK2_ST	Q8TEW0	PARD3	Q7KZI7	MARK2	T453	V447L	447	Missense	distal	-6	no	281.736	282.817	EPSD	COSMIC	271.430	Up-regulation
CAMK_CAMKL_MARK_MARK2_ST	Q8TEW0	PARD3	Q7KZI7	MARK2	T453	R459W	459	Missense	distal	6	no	281.736	268.958	EPSD	COSMIC	271.430	Loss
CAMK_CAMKL_MARK_MARK2_ST	Q8TEW0	PARD3	Q7KZI7	MARK2	T453	K455N	455	Missense	proximal	2	no	281.736	312.451	EPSD	COSMIC	271.430	Up-regulation
CAMK_CAMKL_MARK_MARK2_ST	Q8TEW0	PARD3	Q7KZI7	MARK2	T453	K455I	455	Missense	proximal	2	no	281.736	283.348	EPSD	COSMIC	271.430	Up-regulation
CAMK_CAMKL_MARK_MARK2_ST	Q8TEW0	PARD3	Q7KZI7	MARK2	T453	G457R	457	Missense	distal	4	no	281.736	221.379	EPSD	COSMIC	271.430	Loss
CAMK_CAMKL_MARK_MARK2_ST	Q8TEW0	PARD3	Q7KZI7	MARK2	T468	G472V	472	Missense	distal	4	no	273.513	248.298	EPSD	COSMIC	271.430	Loss
CAMK_CAMKL_MARK_MARK2_ST	Q8TEW0	PARD3	Q7KZI7	MARK2	S477	G472V	472	Missense	distal	-5	no	264.710	271.594	EPSD	COSMIC	271.430	Gain
CAMK_CAMKL_MARK_MARK2_ST	Q8TEW0	PARD3	Q7KZI7	MARK2	T481	S485L	485	Missense	distal	4	no	192.957	278.492	EPSD	COSMIC	271.430	Gain
CAMK_CAMKL_MARK_MARK2_ST	Q8TEW0	PARD3	Q7KZI7	MARK2	S596	V591D	591	Missense	distal	-5	no	364.172	356.030	EPSD	COSMIC	271.430	Down-regulation
CAMK_CAMKL_MARK_MARK2_ST	Q8TEW0	PARD3	Q7KZI7	MARK2	S598	V591D	591	Missense	distal	-7	no	286.486	286.418	EPSD	COSMIC	271.430	Down-regulation
CAMK_CAMKL_MARK_MARK2_ST	Q8TEW0	PARD3	Q7KZI7	MARK2	S604	S610C	610	Missense	distal	6	no	274.692	279.995	EPSD	COSMIC	271.430	Up-regulation
CAMK_CAMKL_MARK_MARK2_ST	Q8TEW0	PARD3	Q7KZI7	MARK2	S604	R609P	609	Missense	distal	5	no	274.692	266.434	EPSD	COSMIC	271.430	Loss
CAMK_CAMKL_MARK_MARK2_ST	Q8TEW0	PARD3	Q7KZI7	MARK2	S604	S610F	610	Missense	distal	6	no	274.692	277.424	EPSD	COSMIC	271.430	Up-regulation
CAMK_CAMKL_MARK_MARK2_ST	Q8TEW0	PARD3	Q7KZI7	MARK2	S667	G670S	670	Missense	distal	3	no	337.841	345.730	EPSD	COSMIC	271.430	Up-regulation
CAMK_CAMKL_MARK_MARK2_ST	Q8TEW0	PARD3	Q7KZI7	MARK2	S685	L678I	678	Missense	distal	-7	no	319.129	319.234	EPSD	COSMIC	271.430	Up-regulation
CAMK_CAMKL_MARK_MARK2_ST	Q8TEW0	PARD3	Q7KZI7	MARK2	S685	V680F	680	Missense	distal	-5	no	319.129	309.575	EPSD	COSMIC	271.430	Down-regulation
CAMK_CAMKL_MARK_MARK2_ST	Q8TEW0	PARD3	Q7KZI7	MARK2	S685	R682K	682	Missense	distal	-3	no	319.129	311.479	EPSD	COSMIC	271.430	Down-regulation
CAMK_CAMKL_MARK_MARK2_ST	Q8TEW0	PARD3	Q7KZI7	MARK2	S685	V680G	680	Missense	distal	-5	no	319.129	312.244	EPSD	COSMIC	271.430	Down-regulation
CAMK_CAMKL_MARK_MARK2_ST	Q8TEW0	PARD3	Q7KZI7	MARK2	S685	R683K	683	Missense	proximal	-2	no	319.129	317.702	EPSD	COSMIC	271.430	Down-regulation
CAMK_CAMKL_MARK_MARK2_ST	Q8TEW0	PARD3	Q7KZI7	MARK2	S728	L735I	735	Missense	distal	7	no	310.369	309.496	EPSD	COSMIC	271.430	Down-regulation
CAMK_CAMKL_MARK_MARK2_ST	Q8TEW0	PARD3	Q7KZI7	MARK2	S728	A734V	734	Missense	distal	6	no	310.369	313.527	EPSD	COSMIC	271.430	Up-regulation
CAMK_CAMKL_MARK_MARK2_ST	Q8TEW0	PARD3	Q7KZI7	MARK2	S748	N752I	752	Missense	distal	4	no	307.606	281.954	EPSD	COSMIC	271.430	Down-regulation
CAMK_CAMKL_MARK_MARK2_ST	Q8TEW0	PARD3	Q7KZI7	MARK2	S748	V751L	751	Missense	distal	3	no	307.606	297.733	EPSD	COSMIC	271.430	Down-regulation
CAMK_CAMKL_MARK_MARK2_ST	Q8TEW0	PARD3	Q7KZI7	MARK2	S807	A804V	804	Missense	distal	-3	no	312.349	366.274	EPSD	COSMIC	271.430	Up-regulation
CAMK_CAMKL_MARK_MARK2_ST	Q8TEW0	PARD3	Q7KZI7	MARK2	S809	A804V	804	Missense	distal	-5	no	278.874	292.012	EPSD	COSMIC	271.430	Up-regulation
CAMK_CAMKL_MARK_MARK2_ST	Q8TEW0	PARD3	Q7KZI7	MARK2	S827	S829T	829	Missense	proximal	2	no	299.784	269.417	EPSD	COSMIC	271.430	Loss
CAMK_CAMKL_MARK_MARK2_ST	Q8TEW0	PARD3	Q7KZI7	MARK2	S827	G822E	822	Missense	distal	-5	no	299.784	297.681	EPSD	COSMIC	271.430	Down-regulation
CAMK_CAMKL_MARK_MARK2_ST	Q8TEW0	PARD3	Q7KZI7	MARK2	S827	R832C	832	Missense	distal	5	no	299.784	285.322	EPSD	COSMIC	271.430	Down-regulation
CAMK_CAMKL_MARK_MARK2_ST	Q8TEW0	PARD3	Q7KZI7	MARK2	S827	M828L	828	Missense	proximal	1	no	299.784	300.521	EPSD	COSMIC	271.430	Up-regulation
CAMK_CAMKL_MARK_MARK2_ST	Q8TEW0	PARD3	Q7KZI7	MARK2	S827	R820C	820	Missense	distal	-7	no	299.784	299.803	EPSD	COSMIC	271.430	Up-regulation
CAMK_CAMKL_MARK_MARK2_ST	Q8TEW0	PARD3	Q7KZI7	MARK2	S827	T833A	833	Missense	distal	6	no	299.784	295.660	EPSD	COSMIC	271.430	Down-regulation
CAMK_CAMKL_MARK_MARK2_ST	Q8TEW0	PARD3	Q7KZI7	MARK2	S850	T847K	847	Missense	distal	-3	no	252.855	338.449	EPSD	COSMIC	271.430	Gain
CAMK_CAMKL_MARK_MARK2_ST	Q8TEW0	PARD3	Q7KZI7	MARK2	S852	T847K	847	Missense	distal	-5	no	338.054	342.234	EPSD	COSMIC	271.430	Up-regulation
CAMK_CAMKL_MARK_MARK2_ST	Q8TEW0	PARD3	Q7KZI7	MARK2	S852	V845I	845	Missense	distal	-7	no	338.054	338.120	EPSD	COSMIC	271.430	Up-regulation
CAMK_CAMKL_MARK_MARK2_ST	Q8TEW0	PARD3	Q7KZI7	MARK2	S852	V845L	845	Missense	distal	-7	no	338.054	338.014	EPSD	COSMIC	271.430	Down-regulation
CAMK_CAMKL_MARK_MARK2_ST	Q8TEW0	PARD3	Q7KZI7	MARK2	S852	D859A	859	Missense	distal	7	no	338.054	333.624	EPSD	COSMIC	271.430	Down-regulation
CAMK_CAMKL_MARK_MARK2_ST	Q8TEW0	PARD3	Q7KZI7	MARK2	S852	D859N	859	Missense	distal	7	no	338.054	354.611	EPSD	COSMIC	271.430	Up-regulation
CAMK_CAMKL_MARK_MARK2_ST	Q8TEW0	PARD3	Q7KZI7	MARK2	S873	P880A	880	Missense	distal	7	no	341.821	333.861	PhosphoSitePlus;EPSD	COSMIC	271.430	Down-regulation
CAMK_CAMKL_MARK_MARK2_ST	Q8TEW0	PARD3	Q7KZI7	MARK2	S873	D868G	868	Missense	distal	-5	no	341.821	343.079	PhosphoSitePlus;EPSD	COSMIC	271.430	Up-regulation
CAMK_CAMKL_MARK_MARK2_ST	Q8TEW0	PARD3	Q7KZI7	MARK2	S873	P874F	874	Missense	proximal	1	no	341.821	341.081	PhosphoSitePlus;EPSD	COSMIC	271.430	Down-regulation
CAMK_CAMKL_MARK_MARK2_ST	Q8TEW0	PARD3	Q7KZI7	MARK2	S873	D867E	867	Missense	distal	-6	no	341.821	340.615	PhosphoSitePlus;EPSD	COSMIC	271.430	Down-regulation
CAMK_CAMKL_MARK_MARK2_ST	Q8TEW0	PARD3	Q7KZI7	MARK2	S875	P880A	880	Missense	distal	5	no	281.356	275.026	EPSD	COSMIC	271.430	Down-regulation
CAMK_CAMKL_MARK_MARK2_ST	Q8TEW0	PARD3	Q7KZI7	MARK2	S875	D868G	868	Missense	distal	-7	no	281.356	281.487	EPSD	COSMIC	271.430	Up-regulation
CAMK_CAMKL_MARK_MARK2_ST	Q8TEW0	PARD3	Q7KZI7	MARK2	S875	P874F	874	Missense	proximal	-1	no	281.356	291.081	EPSD	COSMIC	271.430	Up-regulation
CAMK_CAMKL_MARK_MARK2_ST	Q8TEW0	PARD3	Q7KZI7	MARK2	S875	S873T	873	Missense	proximal	-2	no	281.356	279.313	EPSD	COSMIC	271.430	Down-regulation
CAMK_CAMKL_MARK_MARK2_ST	Q8TEW0	PARD3	Q7KZI7	MARK2	S881	G883C	883	Missense	proximal	2	no	271.305	289.081	EPSD	COSMIC	271.430	Gain
CAMK_CAMKL_MARK_MARK2_ST	Q8TEW0	PARD3	Q7KZI7	MARK2	S881	P880A	880	Missense	proximal	-1	no	271.305	273.759	EPSD	COSMIC	271.430	Gain
CAMK_CAMKL_MARK_MARK2_ST	Q8TEW0	PARD3	Q7KZI7	MARK2	S881	S887F	887	Missense	distal	6	no	271.305	274.037	EPSD	COSMIC	271.430	Gain
CAMK_CAMKL_MARK_MARK2_ST	Q8TEW0	PARD3	Q7KZI7	MARK2	S887	G883C	883	Missense	distal	-4	no	300.286	313.664	EPSD	COSMIC	271.430	Up-regulation
CAMK_CAMKL_MARK_MARK2_ST	Q8TEW0	PARD3	Q7KZI7	MARK2	S887	P880A	880	Missense	distal	-7	no	300.286	300.372	EPSD	COSMIC	271.430	Up-regulation
CAMK_CAMKL_MARK_MARK2_ST	Q8TEW0	PARD3	Q7KZI7	MARK2	S887	K885Q	885	Missense	proximal	-2	no	300.286	300.302	EPSD	COSMIC	271.430	Up-regulation
CAMK_CAMKL_MARK_MARK2_ST	Q8TEW0	PARD3	Q7KZI7	MARK2	S887	Q894K	894	Missense	distal	7	no	300.286	321.030	EPSD	COSMIC	271.430	Up-regulation
CAMK_CAMKL_MARK_MARK2_ST	Q8TEW0	PARD3	Q7KZI7	MARK2	S887	S892G	892	Missense	distal	5	no	300.286	281.646	EPSD	COSMIC	271.430	Down-regulation
CAMK_CAMKL_MARK_MARK2_ST	Q8TEW0	PARD3	Q7KZI7	MARK2	S887	S887F	887	Missense	central	0	yes	300.286	0.000	EPSD	COSMIC	271.430	Loss
CAMK_CAMKL_MARK_MARK2_ST	Q8TEW0	PARD3	Q7KZI7	MARK2	S888	S892G	892	Missense	distal	4	no	203.275	290.936	EPSD	COSMIC	271.430	Gain
CAMK_CAMKL_MARK_MARK2_ST	Q8TEW0	PARD3	Q7KZI7	MARK2	S889	G883C	883	Missense	distal	-6	no	325.266	325.943	EPSD	COSMIC	271.430	Up-regulation
CAMK_CAMKL_MARK_MARK2_ST	Q8TEW0	PARD3	Q7KZI7	MARK2	S889	K885Q	885	Missense	distal	-4	no	325.266	317.712	EPSD	COSMIC	271.430	Down-regulation
CAMK_CAMKL_MARK_MARK2_ST	Q8TEW0	PARD3	Q7KZI7	MARK2	S889	Q894K	894	Missense	distal	5	no	325.266	338.173	EPSD	COSMIC	271.430	Up-regulation
CAMK_CAMKL_MARK_MARK2_ST	Q8TEW0	PARD3	Q7KZI7	MARK2	S889	S892G	892	Missense	distal	3	no	325.266	317.378	EPSD	COSMIC	271.430	Down-regulation
CAMK_CAMKL_MARK_MARK2_ST	Q8TEW0	PARD3	Q7KZI7	MARK2	S889	S887F	887	Missense	proximal	-2	no	325.266	323.116	EPSD	COSMIC	271.430	Down-regulation
CAMK_CAMKL_MARK_MARK2_ST	Q8TEW0	PARD3	Q7KZI7	MARK2	T1048	E1045K	1045	Missense	distal	-3	no	174.787	287.311	EPSD	COSMIC	271.430	Gain
CAMK_CAMKL_MARK_MARK2_ST	Q8TEW0	PARD3	Q7KZI7	MARK2	S1107	R1113C	1113	Missense	distal	6	no	293.283	293.533	EPSD	COSMIC	271.430	Up-regulation
CAMK_CAMKL_MARK_MARK2_ST	Q8TEW0	PARD3	Q7KZI7	MARK2	S1107	S1103F	1103	Missense	distal	-4	no	293.283	287.703	EPSD	COSMIC	271.430	Down-regulation
CAMK_CAMKL_MARK_MARK2_ST	Q8TEW0	PARD3	Q7KZI7	MARK2	S1107	S1102F	1102	Missense	distal	-5	no	293.283	300.126	EPSD	COSMIC	271.430	Up-regulation
CAMK_CAMKL_MARK_MARK2_ST	Q8TEW0	PARD3	Q7KZI7	MARK2	S1107	G1100R	1100	Missense	distal	-7	no	293.283	293.166	EPSD	COSMIC	271.430	Down-regulation
CAMK_CAMKL_MARK_MARK2_ST	Q8TEW0	PARD3	Q7KZI7	MARK2	S1116	R1113C	1113	Missense	distal	-3	no	320.292	227.485	EPSD	COSMIC	271.430	Loss
CAMK_CAMKL_MARK_MARK2_ST	Q8TEW0	PARD3	Q7KZI7	MARK2	S1116	R1118Q	1118	Missense	proximal	2	no	320.292	302.991	EPSD	COSMIC	271.430	Down-regulation
CAMK_CAMKL_MARK_MARK2_ST	Q8TEW0	PARD3	Q7KZI7	MARK2	S1116	R1118W	1118	Missense	proximal	2	no	320.292	284.947	EPSD	COSMIC	271.430	Down-regulation
CAMK_CAMKL_MARK_MARK2_ST	Q8TEW0	PARD3	Q7KZI7	MARK2	S1116	P1117L	1117	Missense	proximal	1	no	320.292	327.063	EPSD	COSMIC	271.430	Up-regulation
CAMK_CAMKL_MARK_MARK2_ST	Q8TEW0	PARD3	Q7KZI7	MARK2	S1146	R1153H	1153	Missense	distal	7	no	274.761	265.766	EPSD	COSMIC	271.430	Loss
CAMK_CAMKL_MARK_MARK2_ST	Q8TEW0	PARD3	Q7KZI7	MARK2	S1146	S1149Y	1149	Missense	distal	3	no	274.761	268.314	EPSD	COSMIC	271.430	Loss
CAMK_CAMKL_MARK_MARK2_ST	Q8TEW0	PARD3	Q7KZI7	MARK2	S1146	S1149F	1149	Missense	distal	3	no	274.761	268.454	EPSD	COSMIC	271.430	Loss
CAMK_CAMKL_MARK_MARK2_ST	Q8TEW0	PARD3	Q7KZI7	MARK2	S1146	S1146F	1146	Missense	central	0	yes	274.761	0.000	EPSD	COSMIC	271.430	Loss
CAMK_CAMKL_MARK_MARK2_ST	Q8TEW0	PARD3	Q7KZI7	MARK2	S1146	S1149G	1149	Missense	distal	3	no	274.761	266.873	EPSD	COSMIC	271.430	Loss
CAMK_CAMKL_MARK_MARK2_ST	Q8TEW0	PARD3	Q7KZI7	MARK2	S1146	P1148T	1148	Missense	proximal	2	no	274.761	259.117	EPSD	COSMIC	271.430	Loss
CAMK_CAMKL_MARK_MARK2_ST	Q8TEW0	PARD3	Q7KZI7	MARK2	S1146	T1147S	1147	Missense	proximal	1	no	274.761	273.433	EPSD	COSMIC	271.430	Down-regulation
CAMK_CAMKL_MARK_MARK2_ST	Q8TEW0	PARD3	Q7KZI7	MARK2	S1146	V1141I	1141	Missense	distal	-5	no	274.761	267.972	EPSD	COSMIC	271.430	Loss
CAMK_CAMKL_MARK_MARK2_ST	Q8TEW0	PARD3	Q7KZI7	MARK2	S1146	H1151N	1151	Missense	distal	5	no	274.761	281.460	EPSD	COSMIC	271.430	Up-regulation
CAMK_CAMKL_MARK_MARK2_ST	Q8TEW0	PARD3	Q7KZI7	MARK2	T1147	R1153H	1153	Missense	distal	6	no	301.491	301.243	EPSD	COSMIC	271.430	Down-regulation
CAMK_CAMKL_MARK_MARK2_ST	Q8TEW0	PARD3	Q7KZI7	MARK2	T1147	S1149Y	1149	Missense	proximal	2	no	301.491	284.076	EPSD	COSMIC	271.430	Down-regulation
CAMK_CAMKL_MARK_MARK2_ST	Q8TEW0	PARD3	Q7KZI7	MARK2	T1147	S1149F	1149	Missense	proximal	2	no	301.491	269.317	EPSD	COSMIC	271.430	Loss
CAMK_CAMKL_MARK_MARK2_ST	Q8TEW0	PARD3	Q7KZI7	MARK2	T1147	S1146F	1146	Missense	proximal	-1	no	301.491	300.015	EPSD	COSMIC	271.430	Down-regulation
CAMK_CAMKL_MARK_MARK2_ST	Q8TEW0	PARD3	Q7KZI7	MARK2	T1147	S1149G	1149	Missense	proximal	2	no	301.491	274.919	EPSD	COSMIC	271.430	Down-regulation
CAMK_CAMKL_MARK_MARK2_ST	Q8TEW0	PARD3	Q7KZI7	MARK2	T1147	P1148T	1148	Missense	proximal	1	no	301.491	305.101	EPSD	COSMIC	271.430	Up-regulation
CAMK_CAMKL_MARK_MARK2_ST	Q8TEW0	PARD3	Q7KZI7	MARK2	T1147	V1141I	1141	Missense	distal	-6	no	301.491	301.498	EPSD	COSMIC	271.430	Up-regulation
CAMK_CAMKL_MARK_MARK2_ST	Q8TEW0	PARD3	Q7KZI7	MARK2	T1147	H1151N	1151	Missense	distal	4	no	301.491	320.482	EPSD	COSMIC	271.430	Up-regulation
CAMK_CAMKL_MARK_MARK2_ST	Q8TEW0	PARD3	Q7KZI7	MARK2	S1149	R1153H	1153	Missense	distal	4	no	271.305	312.108	EPSD	COSMIC	271.430	Gain
CAMK_CAMKL_MARK_MARK2_ST	Q8TEW0	PARD3	Q7KZI7	MARK2	S1149	T1147S	1147	Missense	proximal	-2	no	271.305	273.348	EPSD	COSMIC	271.430	Gain
CAMK_CAMKL_MARK_MARK2_ST	Q8TEW0	PARD3	Q7KZI7	MARK2	S1149	H1151N	1151	Missense	proximal	2	no	271.305	295.201	EPSD	COSMIC	271.430	Gain
CAMK_CAMKL_MARK_MARK2_ST	Q8TEW0	PARD3	Q7KZI7	MARK2	T1176	E1180G	1180	Missense	distal	4	no	235.150	271.787	EPSD	COSMIC	271.430	Gain
CAMK_CAMKL_MARK_MARK2_ST	Q8TEW0	PARD3	Q7KZI7	MARK2	S1196	S1192G	1192	Missense	distal	-4	no	275.712	273.472	EPSD	COSMIC	271.430	Down-regulation
CAMK_CAMKL_MARK_MARK2_ST	Q8TEW0	PARD3	Q7KZI7	MARK2	S1196	Q1202H	1202	Missense	distal	6	no	275.712	287.838	EPSD	COSMIC	271.430	Up-regulation
CAMK_CAMKL_MARK_MARK2_ST	Q8TEW0	PARD3	Q7KZI7	MARK2	S1196	T1190M	1190	Missense	distal	-6	no	275.712	274.918	EPSD	COSMIC;GDSC	271.430	Down-regulation
CAMK_CAMKL_MARK_MARK2_ST	Q8TEW0	PARD3	Q7KZI7	MARK2	S1198	Q1202H	1202	Missense	distal	4	no	182.882	285.730	EPSD	COSMIC	271.430	Gain
CAMK_CAMKL_MARK_MARK2_ST	Q8TEW0	PARD3	Q7KZI7	MARK2	S1222	R1226L	1226	Missense	distal	4	no	226.449	284.679	EPSD	COSMIC	271.430	Gain
CAMK_CAMKL_MARK_MARK2_ST	Q8TEW0	PARD3	Q7KZI7	MARK2	S1252	S1252L	1252	Missense	central	0	yes	302.550	0.000	EPSD	COSMIC	271.430	Loss
CAMK_CAMKL_MARK_MARK2_ST	Q8TEW0	PARD3	Q7KZI7	MARK2	S1252	Y1259C	1259	Missense	distal	7	no	302.550	302.759	EPSD	COSMIC	271.430	Up-regulation
CAMK_CAMKL_MARK_MARK2_ST	Q8TEW0	PARD3	Q7KZI7	MARK2	S1252	P1246T	1246	Missense	distal	-6	no	302.550	303.474	EPSD	COSMIC	271.430	Up-regulation
CAMK_CAMKL_MARK_MARK2_ST	Q8TEW0	PARD3	Q7KZI7	MARK2	S1252	P1257L	1257	Missense	distal	5	no	302.550	316.591	EPSD	COSMIC	271.430	Up-regulation
CAMK_CAMKL_MARK_MARK2_ST	Q8TEW0	PARD3	Q7KZI7	MARK2	S1252	Q1251E	1251	Missense	proximal	-1	no	302.550	313.162	EPSD	COSMIC	271.430	Up-regulation
CAMK_CAMKL_MARK_MARK2_ST	Q8TEW0	PARD3	Q7KZI7	MARK2	S1252	S1245G	1245	Missense	distal	-7	no	302.550	302.690	EPSD	COSMIC	271.430	Up-regulation
CAMK_CAMKL_MARK_MARK2_ST	Q8TEW0	PARD3	Q7KZI7	MARK2	S1252	S1245Y	1245	Missense	distal	-7	no	302.550	302.607	EPSD	COSMIC	271.430	Up-regulation
CAMK_CAMKL_MARK_MARK2_ST	Q8TEW0	PARD3	Q7KZI7	MARK2	S1252	S1252G	1252	Missense	central	0	yes	302.550	0.000	EPSD	COSMIC	271.430	Loss
CAMK_CAMKL_MARK_MARK2_ST	Q8TEW0	PARD3	Q7KZI7	MARK2	S1252	A1253V	1253	Missense	proximal	1	no	302.550	313.016	EPSD	COSMIC	271.430	Up-regulation
CAMK_CAMKL_MARK_MARK2_ST	Q8TEW0	PARD3	Q7KZI7	MARK2	S1252	E1255K	1255	Missense	distal	3	no	302.550	293.850	EPSD	COSMIC	271.430	Down-regulation
CAMK_CAMKL_MARK_MARK2_ST	Q8TEW0	PARD3	Q7KZI7	MARK2	S1337	Q1330K	1330	Missense	distal	-7	no	283.746	283.721	EPSD	COSMIC	271.430	Down-regulation
CAMK_CAMKL_MARK_MARK2_ST	Q8TEW0	PARD3	Q7KZI7	MARK2	S1337	R1341S	1341	Missense	distal	4	no	283.746	256.441	EPSD	COSMIC	271.430	Loss
CAMK_CAMKL_MARK_MARK2_ST	Q8TEW0	PARD3	Q7KZI7	MARK2	S1337	S1337F	1337	Missense	central	0	yes	283.746	0.000	EPSD	COSMIC	271.430	Loss
CAMK_CAMKL_MARK_MARK2_ST	Q8TEW0	PARD3	Q7KZI7	MARK2	S1337	P1336T	1336	Missense	proximal	-1	no	283.746	281.197	EPSD	COSMIC	271.430	Down-regulation
CAMK_CAMKL_MARK_MARK2_ST	Q8TEW0	PARD3	Q7KZI7	MARK2	T1347	G1351W	1351	Missense	distal	4	no	286.323	155.906	EPSD	COSMIC	271.430	Loss
CAMK_CAMKL_MARK_MARK2_ST	Q8TEW0	PARD3	Q7KZI7	MARK2	T1347	K1350N	1350	Missense	distal	3	no	286.323	311.601	EPSD	COSMIC	271.430	Up-regulation
CAMK_CAMKL_MARK_MARK2_ST	Q8TEW0	PARD3	Q7KZI7	MARK2	T1347	R1352G	1352	Missense	distal	5	no	286.323	265.955	EPSD	COSMIC	271.430	Loss
CAMK_CAMKL_MARK_MARK2_ST	Q8TEW0	PARD3	Q7KZI7	MARK2	T1347	R1341S	1341	Missense	distal	-6	no	286.323	286.389	EPSD	COSMIC	271.430	Up-regulation
CAMK_CAMKL_MARK_MARK2_ST	Q8TEW0	PARD3	Q7KZI7	MARK2	T1347	P1353L	1353	Missense	distal	6	no	286.323	300.856	EPSD	COSMIC	271.430	Up-regulation
CAMK_CAMKL_MARK_MARK2_ST	Q8TEW0	PARD3	Q7KZI7	MARK2	T1347	E1349Q	1349	Missense	proximal	2	no	286.323	267.330	EPSD	COSMIC;GDSC;CCLE	271.430	Loss
CAMK_CAMKL_MARK_MARK2_ST	Q7KZI7	MARK2	Q7KZI7	MARK2	S30	L24V	24	Missense	distal	-6	no	286.074	284.992	EPSD	COSMIC	271.430	Down-regulation
CAMK_CAMKL_MARK_MARK2_ST	Q7KZI7	MARK2	Q7KZI7	MARK2	T58	G62S	62	Missense	distal	4	no	331.237	243.575	EPSD	COSMIC	271.430	Loss
CAMK_CAMKL_MARK_MARK2_ST	Q7KZI7	MARK2	Q7KZI7	MARK2	T58	R54L	54	Missense	distal	-4	no	331.237	324.840	EPSD	COSMIC	271.430	Down-regulation
CAMK_CAMKL_MARK_MARK2_ST	Q7KZI7	MARK2	Q7KZI7	MARK2	T58	N63I	63	Missense	distal	5	no	331.237	325.608	EPSD	COSMIC	271.430	Down-regulation
CAMK_CAMKL_MARK_MARK2_ST	Q7KZI7	MARK2	Q7KZI7	MARK2	S93	N90K	90	Missense	distal	-3	no	282.620	314.536	EPSD	COSMIC	271.430	Up-regulation
CAMK_CAMKL_MARK_MARK2_ST	Q7KZI7	MARK2	Q7KZI7	MARK2	S93	R99H	99	Missense	distal	6	no	282.620	282.373	EPSD	COSMIC	271.430	Down-regulation
CAMK_CAMKL_MARK_MARK2_ST	Q7KZI7	MARK2	Q7KZI7	MARK2	S274	N279Y	279	Missense	distal	5	no	357.007	352.406	EPSD	COSMIC	271.430	Down-regulation
CAMK_CAMKL_MARK_MARK2_ST	Q7KZI7	MARK2	Q7KZI7	MARK2	S274	T275M	275	Missense	proximal	1	no	357.007	359.431	EPSD	COSMIC	271.430	Up-regulation
CAMK_CAMKL_MARK_MARK2_ST	Q7KZI7	MARK2	Q7KZI7	MARK2	S274	Y267H	267	Missense	distal	-7	no	357.007	357.030	EPSD	COSMIC	271.430	Up-regulation
CAMK_CAMKL_MARK_MARK2_ST	Q7KZI7	MARK2	Q7KZI7	MARK2	T275	N279Y	279	Missense	distal	4	no	351.104	249.188	EPSD	COSMIC	271.430	Loss
CAMK_CAMKL_MARK_MARK2_ST	Q7KZI7	MARK2	Q7KZI7	MARK2	T275	T275M	275	Missense	central	0	yes	351.104	0.000	EPSD	COSMIC	271.430	Loss
CAMK_CAMKL_MARK_MARK2_ST	Q7KZI7	MARK2	Q7KZI7	MARK2	S365	T372I	372	Missense	distal	7	no	277.431	274.861	EPSD	COSMIC	271.430	Down-regulation
CAMK_CAMKL_MARK_MARK2_ST	Q7KZI7	MARK2	Q7KZI7	MARK2	S400	R407H	407	Missense	distal	7	no	345.504	336.508	PhosphoSitePlus	COSMIC	271.430	Down-regulation
CAMK_CAMKL_MARK_MARK2_ST	Q7KZI7	MARK2	Q7KZI7	MARK2	S400	R406Q	406	Missense	distal	6	no	345.504	333.130	PhosphoSitePlus	COSMIC	271.430	Down-regulation
CAMK_CAMKL_MARK_MARK2_ST	Q7KZI7	MARK2	Q7KZI7	MARK2	S409	R407H	407	Missense	proximal	-2	no	292.182	291.951	EPSD	COSMIC	271.430	Down-regulation
CAMK_CAMKL_MARK_MARK2_ST	Q7KZI7	MARK2	Q7KZI7	MARK2	S409	R406Q	406	Missense	distal	-3	no	292.182	190.139	EPSD	COSMIC	271.430	Loss
CAMK_CAMKL_MARK_MARK2_ST	Q7KZI7	MARK2	Q7KZI7	MARK2	S449	S443F	443	Missense	distal	-6	no	303.866	303.078	EPSD	COSMIC	271.430	Down-regulation
CAMK_CAMKL_MARK_MARK2_ST	Q7KZI7	MARK2	Q7KZI7	MARK2	S449	S448N	448	Missense	proximal	-1	no	303.866	299.918	EPSD	COSMIC	271.430	Down-regulation
CAMK_CAMKL_MARK_MARK2_ST	Q7KZI7	MARK2	Q7KZI7	MARK2	S449	S449N	449	Missense	central	0	yes	303.866	0.000	EPSD	COSMIC	271.430	Loss
CAMK_CAMKL_MARK_MARK2_ST	Q7KZI7	MARK2	Q7KZI7	MARK2	T472	P470S	470	Missense	proximal	-2	no	279.505	281.433	EPSD	COSMIC	271.430	Up-regulation
CAMK_CAMKL_MARK_MARK2_ST	Q7KZI7	MARK2	Q7KZI7	MARK2	T472	S477F	477	Missense	distal	5	no	279.505	270.171	EPSD	COSMIC	271.430	Loss
CAMK_CAMKL_MARK_MARK2_ST	Q7KZI7	MARK2	Q7KZI7	MARK2	S477	P470S	470	Missense	distal	-7	no	301.523	301.469	EPSD	COSMIC	271.430	Down-regulation
CAMK_CAMKL_MARK_MARK2_ST	Q7KZI7	MARK2	Q7KZI7	MARK2	S477	S477F	477	Missense	central	0	yes	301.523	0.000	EPSD	COSMIC	271.430	Loss
CAMK_CAMKL_MARK_MARK2_ST	Q7KZI7	MARK2	Q7KZI7	MARK2	S498	A492T	492	Missense	distal	-6	no	277.905	278.332	EPSD	COSMIC	271.430	Up-regulation
CAMK_CAMKL_MARK_MARK2_ST	Q7KZI7	MARK2	Q7KZI7	MARK2	S533	P540L	540	Missense	distal	7	no	274.130	277.764	EPSD	COSMIC	271.430	Up-regulation
CAMK_CAMKL_MARK_MARK2_ST	Q7KZI7	MARK2	Q7KZI7	MARK2	S533	R526W	526	Missense	distal	-7	no	274.130	274.305	EPSD	COSMIC	271.430	Up-regulation
CAMK_CAMKL_MARK_MARK2_ST	Q7KZI7	MARK2	Q7KZI7	MARK2	S533	P527S	527	Missense	distal	-6	no	274.130	274.788	EPSD	COSMIC	271.430	Up-regulation
CAMK_CAMKL_MARK_MARK2_ST	Q7KZI7	MARK2	Q7KZI7	MARK2	S533	P527Q	527	Missense	distal	-6	no	274.130	274.172	EPSD	COSMIC	271.430	Up-regulation
CAMK_CAMKL_MARK_MARK2_ST	Q7KZI7	MARK2	Q7KZI7	MARK2	S533	A536V	536	Missense	distal	3	no	274.130	305.799	EPSD	COSMIC	271.430	Up-regulation
CAMK_CAMKL_MARK_MARK2_ST	Q7KZI7	MARK2	Q7KZI7	MARK2	S533	S535F	535	Missense	proximal	2	no	274.130	241.956	EPSD	COSMIC	271.430	Loss
CAMK_CAMKL_MARK_MARK2_ST	Q7KZI7	MARK2	Q7KZI7	MARK2	S535	P540L	540	Missense	distal	5	no	363.949	377.990	EPSD	COSMIC	271.430	Up-regulation
CAMK_CAMKL_MARK_MARK2_ST	Q7KZI7	MARK2	Q7KZI7	MARK2	S535	A536V	536	Missense	proximal	1	no	363.949	374.415	EPSD	COSMIC	271.430	Up-regulation
CAMK_CAMKL_MARK_MARK2_ST	Q7KZI7	MARK2	Q7KZI7	MARK2	S535	S535F	535	Missense	central	0	yes	363.949	0.000	EPSD	COSMIC	271.430	Loss
CAMK_CAMKL_MARK_MARK2_ST	Q7KZI7	MARK2	Q7KZI7	MARK2	T560	R564H	564	Missense	distal	4	no	240.376	281.178	EPSD	COSMIC	271.430	Gain
CAMK_CAMKL_MARK_MARK2_ST	Q7KZI7	MARK2	Q7KZI7	MARK2	S569	P566L	566	Missense	distal	-3	no	253.797	289.269	EPSD	COSMIC	271.430	Gain
CAMK_CAMKL_MARK_MARK2_ST	Q7KZI7	MARK2	Q7KZI7	MARK2	S577	G580D	580	Missense	distal	3	no	241.069	297.808	EPSD	COSMIC	271.430	Gain
CAMK_CAMKL_MARK_MARK2_ST	Q7KZI7	MARK2	Q7KZI7	MARK2	S631	R627H	627	Missense	distal	-4	no	331.187	317.272	EPSD	COSMIC	271.430	Down-regulation
CAMK_CAMKL_MARK_MARK2_ST	Q7KZI7	MARK2	Q7KZI7	MARK2	S631	R627L	627	Missense	distal	-4	no	331.187	324.790	EPSD	COSMIC	271.430	Down-regulation
CAMK_CAMKL_MARK_MARK2_ST	Q7KZI7	MARK2	Q7KZI7	MARK2	S631	R627C	627	Missense	distal	-4	no	331.187	342.724	EPSD	COSMIC	271.430	Up-regulation
CAMK_CAMKL_MARK_MARK2_ST	Q7KZI7	MARK2	Q7KZI7	MARK2	S631	K637T	637	Missense	distal	6	no	331.187	328.372	EPSD	COSMIC	271.430	Down-regulation
CAMK_CAMKL_MARK_MARK2_ST	Q7KZI7	MARK2	Q7KZI7	MARK2	S640	K641R	641	Missense	proximal	1	no	286.099	290.854	EPSD	COSMIC	271.430	Up-regulation
CAMK_CAMKL_MARK_MARK2_ST	Q7KZI7	MARK2	Q7KZI7	MARK2	S640	K637T	637	Missense	distal	-3	no	286.099	200.505	EPSD	COSMIC	271.430	Loss
CAMK_CAMKL_MARK_MARK2_ST	Q7KZI7	MARK2	Q7KZI7	MARK2	S648	R654Q	654	Missense	distal	6	no	312.222	299.849	EPSD	COSMIC	271.430	Down-regulation
CAMK_CAMKL_MARK_MARK2_ST	Q7KZI7	MARK2	Q7KZI7	MARK2	S648	K641R	641	Missense	distal	-7	no	312.222	312.161	EPSD	COSMIC	271.430	Down-regulation
CAMK_CAMKL_MARK_MARK2_ST	Q7KZI7	MARK2	Q7KZI7	MARK2	T667	E660Q	660	Missense	distal	-7	no	311.074	311.053	EPSD	COSMIC	271.430	Down-regulation
CAMK_CAMKL_MARK_MARK2_ST	Q7KZI7	MARK2	Q7KZI7	MARK2	T667	R664Q	664	Missense	distal	-3	no	311.074	209.032	EPSD	COSMIC	271.430	Loss
CAMK_CAMKL_MARK_MARK2_ST	Q7KZI7	MARK2	Q7KZI7	MARK2	T667	R669L	669	Missense	proximal	2	no	311.074	298.077	EPSD	COSMIC	271.430	Down-regulation
CAMK_CAMKL_MARK_MARK2_ST	Q7KZI7	MARK2	Q7KZI7	MARK2	T667	E666G	666	Missense	proximal	-1	no	311.074	321.720	EPSD	COSMIC	271.430	Up-regulation
CAMK_CAMKL_MARK_MARK2_ST	Q92974	ARHGEF2	Q7KZI7	MARK2	S6	R3W	3	Missense	distal	-3	no	286.639	139.099	EPSD	COSMIC	271.430	Loss
CAMK_CAMKL_MARK_MARK2_ST	Q92974	ARHGEF2	Q7KZI7	MARK2	S6	E5A	5	Missense	proximal	-1	no	286.639	287.190	EPSD	COSMIC;CCLE	271.430	Up-regulation
CAMK_CAMKL_MARK_MARK2_ST	Q92974	ARHGEF2	Q7KZI7	MARK2	S137	R141L	141	Missense	distal	4	no	240.812	299.041	EPSD	COSMIC	271.430	Gain
CAMK_CAMKL_MARK_MARK2_ST	Q92974	ARHGEF2	Q7KZI7	MARK2	S142	S137F	137	Missense	distal	-5	no	302.986	309.830	EPSD	COSMIC	271.430	Up-regulation
CAMK_CAMKL_MARK_MARK2_ST	Q92974	ARHGEF2	Q7KZI7	MARK2	S142	R138S	138	Missense	distal	-4	no	302.986	303.384	EPSD	COSMIC	271.430	Up-regulation
CAMK_CAMKL_MARK_MARK2_ST	Q92974	ARHGEF2	Q7KZI7	MARK2	S142	R141S	141	Missense	proximal	-1	no	302.986	304.480	EPSD	COSMIC	271.430	Up-regulation
CAMK_CAMKL_MARK_MARK2_ST	Q92974	ARHGEF2	Q7KZI7	MARK2	S142	R141C	141	Missense	proximal	-1	no	302.986	310.338	EPSD	COSMIC	271.430	Up-regulation
CAMK_CAMKL_MARK_MARK2_ST	Q92974	ARHGEF2	Q7KZI7	MARK2	S142	R141L	141	Missense	proximal	-1	no	302.986	313.046	EPSD	COSMIC	271.430	Up-regulation
CAMK_CAMKL_MARK_MARK2_ST	Q92974	ARHGEF2	Q7KZI7	MARK2	S143	S137F	137	Missense	distal	-6	no	344.445	343.657	EPSD;PhosphoSitePlus	COSMIC	271.430	Down-regulation
CAMK_CAMKL_MARK_MARK2_ST	Q92974	ARHGEF2	Q7KZI7	MARK2	S143	R138S	138	Missense	distal	-5	no	344.445	336.796	EPSD;PhosphoSitePlus	COSMIC	271.430	Down-regulation
CAMK_CAMKL_MARK_MARK2_ST	Q92974	ARHGEF2	Q7KZI7	MARK2	S143	R141S	141	Missense	proximal	-2	no	344.445	345.641	EPSD;PhosphoSitePlus	COSMIC	271.430	Up-regulation
CAMK_CAMKL_MARK_MARK2_ST	Q92974	ARHGEF2	Q7KZI7	MARK2	S143	R141C	141	Missense	proximal	-2	no	344.445	347.098	EPSD;PhosphoSitePlus	COSMIC	271.430	Up-regulation
CAMK_CAMKL_MARK_MARK2_ST	Q92974	ARHGEF2	Q7KZI7	MARK2	S143	R141L	141	Missense	proximal	-2	no	344.445	346.526	EPSD;PhosphoSitePlus	COSMIC	271.430	Up-regulation
CAMK_CAMKL_MARK_MARK2_ST	Q92974	ARHGEF2	Q7KZI7	MARK2	S163	R168L	168	Missense	distal	5	no	307.534	313.316	EPSD	COSMIC	271.430	Up-regulation
CAMK_CAMKL_MARK_MARK2_ST	Q92974	ARHGEF2	Q7KZI7	MARK2	S163	D161N	161	Missense	proximal	-2	no	307.534	310.730	EPSD	COSMIC	271.430	Up-regulation
CAMK_CAMKL_MARK_MARK2_ST	Q92974	ARHGEF2	Q7KZI7	MARK2	S163	P164L	164	Missense	proximal	1	no	307.534	314.305	EPSD	COSMIC	271.430	Up-regulation
CAMK_CAMKL_MARK_MARK2_ST	Q92974	ARHGEF2	Q7KZI7	MARK2	S172	S174P	174	Missense	proximal	2	no	393.740	379.016	EPSD;PhosphoSitePlus	COSMIC	271.430	Down-regulation
CAMK_CAMKL_MARK_MARK2_ST	Q92974	ARHGEF2	Q7KZI7	MARK2	S172	R168L	168	Missense	distal	-4	no	393.740	387.344	EPSD;PhosphoSitePlus	COSMIC	271.430	Down-regulation
CAMK_CAMKL_MARK_MARK2_ST	Q92974	ARHGEF2	Q7KZI7	MARK2	S172	T175K	175	Missense	distal	3	no	393.740	407.278	EPSD;PhosphoSitePlus	COSMIC	271.430	Up-regulation
CAMK_CAMKL_MARK_MARK2_ST	Q92974	ARHGEF2	Q7KZI7	MARK2	S174	S174P	174	Missense	central	0	yes	296.599	0.000	EPSD	COSMIC	271.430	Loss
CAMK_CAMKL_MARK_MARK2_ST	Q92974	ARHGEF2	Q7KZI7	MARK2	S174	R168L	168	Missense	distal	-6	no	296.599	298.216	EPSD	COSMIC	271.430	Up-regulation
CAMK_CAMKL_MARK_MARK2_ST	Q92974	ARHGEF2	Q7KZI7	MARK2	S174	T175K	175	Missense	proximal	1	no	296.599	292.558	EPSD	COSMIC	271.430	Down-regulation
CAMK_CAMKL_MARK_MARK2_ST	Q92974	ARHGEF2	Q7KZI7	MARK2	T175	S174P	174	Missense	proximal	-1	no	275.823	264.622	EPSD	COSMIC	271.430	Loss
CAMK_CAMKL_MARK_MARK2_ST	Q92974	ARHGEF2	Q7KZI7	MARK2	T175	R168L	168	Missense	distal	-7	no	275.823	275.837	EPSD	COSMIC	271.430	Up-regulation
CAMK_CAMKL_MARK_MARK2_ST	Q92974	ARHGEF2	Q7KZI7	MARK2	T175	T175K	175	Missense	central	0	yes	275.823	0.000	EPSD	COSMIC	271.430	Loss
CAMK_CAMKL_MARK_MARK2_ST	Q92974	ARHGEF2	Q7KZI7	MARK2	T184	R183S	183	Missense	proximal	-1	no	303.591	305.085	EPSD	COSMIC	271.430	Up-regulation
CAMK_CAMKL_MARK_MARK2_ST	Q92974	ARHGEF2	Q7KZI7	MARK2	T184	S186F	186	Missense	proximal	2	no	303.591	271.417	EPSD	COSMIC	271.430	Loss
CAMK_CAMKL_MARK_MARK2_ST	Q92974	ARHGEF2	Q7KZI7	MARK2	S186	R183S	183	Missense	distal	-3	no	361.943	293.422	EPSD;PhosphoSitePlus	COSMIC	271.430	Down-regulation
CAMK_CAMKL_MARK_MARK2_ST	Q92974	ARHGEF2	Q7KZI7	MARK2	S186	S186F	186	Missense	central	0	yes	361.943	0.000	EPSD;PhosphoSitePlus	COSMIC	271.430	Loss
CAMK_CAMKL_MARK_MARK2_ST	Q92974	ARHGEF2	Q7KZI7	MARK2	T455	T455K	455	Missense	central	0	yes	337.862	0.000	EPSD	COSMIC	271.430	Loss
CAMK_CAMKL_MARK_MARK2_ST	Q92974	ARHGEF2	Q7KZI7	MARK2	T455	M449I	449	Missense	distal	-6	no	337.862	338.868	EPSD	COSMIC	271.430	Up-regulation
CAMK_CAMKL_MARK_MARK2_ST	Q92974	ARHGEF2	Q7KZI7	MARK2	S519	Q524R	524	Missense	distal	5	no	272.266	281.666	EPSD	COSMIC	271.430	Up-regulation
CAMK_CAMKL_MARK_MARK2_ST	Q92974	ARHGEF2	Q7KZI7	MARK2	S522	Q524R	524	Missense	proximal	2	no	257.815	275.116	EPSD	COSMIC	271.430	Gain
CAMK_CAMKL_MARK_MARK2_ST	Q92974	ARHGEF2	Q7KZI7	MARK2	S719	S721C	721	Missense	proximal	2	no	272.879	264.084	EPSD	COSMIC	271.430	Loss
CAMK_CAMKL_MARK_MARK2_ST	Q92974	ARHGEF2	Q7KZI7	MARK2	S719	D718H	718	Missense	proximal	-1	no	272.879	280.649	EPSD	COSMIC	271.430	Up-regulation
CAMK_CAMKL_MARK_MARK2_ST	Q92974	ARHGEF2	Q7KZI7	MARK2	S782	A780S	780	Missense	proximal	-2	no	276.770	279.364	EPSD	COSMIC	271.430	Up-regulation
CAMK_CAMKL_MARK_MARK2_ST	Q92974	ARHGEF2	Q7KZI7	MARK2	S782	R783Q	783	Missense	proximal	1	no	276.770	270.405	EPSD	COSMIC;CCLE	271.430	Loss
CAMK_CAMKL_MARK_MARK2_ST	Q92974	ARHGEF2	Q7KZI7	MARK2	T802	A801P	801	Missense	proximal	-1	no	282.521	280.067	EPSD	COSMIC	271.430	Down-regulation
CAMK_CAMKL_MARK_MARK2_ST	Q92974	ARHGEF2	Q7KZI7	MARK2	T802	E803K	803	Missense	proximal	1	no	282.521	277.528	EPSD	COSMIC	271.430	Down-regulation
CAMK_CAMKL_MARK_MARK2_ST	Q92974	ARHGEF2	Q7KZI7	MARK2	T802	A801S	801	Missense	proximal	-1	no	282.521	291.268	EPSD	COSMIC	271.430	Up-regulation
CAMK_CAMKL_MARK_MARK2_ST	Q92974	ARHGEF2	Q7KZI7	MARK2	T802	V795M	795	Missense	distal	-7	no	282.521	282.600	EPSD	COSMIC;CCLE	271.430	Up-regulation
CAMK_CAMKL_MARK_MARK2_ST	Q92974	ARHGEF2	Q7KZI7	MARK2	S886	R885W	885	Missense	proximal	-1	no	361.187	343.406	EPSD	COSMIC	271.430	Down-regulation
CAMK_CAMKL_MARK_MARK2_ST	Q92974	ARHGEF2	Q7KZI7	MARK2	S886	R883Q	883	Missense	distal	-3	no	361.187	259.144	EPSD	COSMIC	271.430	Loss
CAMK_CAMKL_MARK_MARK2_ST	Q92974	ARHGEF2	Q7KZI7	MARK2	S886	R884C	884	Missense	proximal	-2	no	361.187	363.839	EPSD	COSMIC	271.430	Up-regulation
CAMK_CAMKL_MARK_MARK2_ST	Q92974	ARHGEF2	Q7KZI7	MARK2	S886	R884H	884	Missense	proximal	-2	no	361.187	360.956	EPSD	COSMIC	271.430	Down-regulation
CAMK_CAMKL_MARK_MARK2_ST	Q92974	ARHGEF2	Q7KZI7	MARK2	S886	R885C	885	Missense	proximal	-1	no	361.187	368.538	EPSD	COSMIC;CCLE	271.430	Up-regulation
CAMK_CAMKL_MARK_MARK2_ST	Q92974	ARHGEF2	Q7KZI7	MARK2	S886	L887F	887	Missense	proximal	1	no	361.187	353.676	EPSD	COSMIC	271.430	Down-regulation
CAMK_CAMKL_MARK_MARK2_ST	Q92974	ARHGEF2	Q7KZI7	MARK2	S886	P882L	882	Missense	distal	-4	no	361.187	348.145	EPSD	COSMIC	271.430	Down-regulation
CAMK_CAMKL_MARK_MARK2_ST	Q92974	ARHGEF2	Q7KZI7	MARK2	S886	P888S	888	Missense	proximal	2	no	361.187	375.911	EPSD	COSMIC	271.430	Up-regulation
CAMK_CAMKL_MARK_MARK2_ST	Q92974	ARHGEF2	Q7KZI7	MARK2	S886	P888L	888	Missense	proximal	2	no	361.187	342.792	EPSD	COSMIC	271.430	Down-regulation
CAMK_CAMKL_MARK_MARK2_ST	Q92974	ARHGEF2	Q7KZI7	MARK2	S940	P933S	933	Missense	distal	-7	no	324.866	324.812	EPSD	COSMIC	271.430	Down-regulation
CAMK_CAMKL_MARK_MARK2_ST	Q92974	ARHGEF2	Q7KZI7	MARK2	S940	S941R	941	Missense	proximal	1	no	324.866	326.909	EPSD	COSMIC	271.430	Up-regulation
CAMK_CAMKL_MARK_MARK2_ST	Q92974	ARHGEF2	Q7KZI7	MARK2	S940	E934K	934	Missense	distal	-6	no	324.866	325.689	EPSD	COSMIC	271.430	Up-regulation
CAMK_CAMKL_MARK_MARK2_ST	Q92974	ARHGEF2	Q7KZI7	MARK2	S940	G946D	946	Missense	distal	6	no	324.866	318.840	EPSD	COSMIC	271.430	Down-regulation
CAMK_CAMKL_MARK_MARK2_ST	Q92974	ARHGEF2	Q7KZI7	MARK2	S960	L955V	955	Missense	distal	-5	no	345.819	352.723	EPSD	COSMIC	271.430	Up-regulation
CAMK_CAMKL_MARK_MARK2_ST	P10636	MAPT	Q7KZI7	MARK2	T17	R23K	23	Missense	distal	6	no	321.150	318.516	EPSD	COSMIC	271.430	Down-regulation
CAMK_CAMKL_MARK_MARK2_ST	P10636	MAPT	Q7KZI7	MARK2	S214	E210Q	210	Missense	distal	-4	no	313.338	306.049	EPSD	COSMIC	271.430	Down-regulation
CAMK_CAMKL_MARK_MARK2_ST	P10636	MAPT	Q7KZI7	MARK2	S214	G207E	207	Missense	distal	-7	no	313.338	313.328	EPSD	COSMIC	271.430	Down-regulation
CAMK_CAMKL_MARK_MARK2_ST	P10636	MAPT	Q7KZI7	MARK2	T386	G385V	385	Missense	proximal	-1	no	328.520	310.577	EPSD	COSMIC	271.430	Down-regulation
CAMK_CAMKL_MARK_MARK2_ST	P10636	MAPT	Q7KZI7	MARK2	T386	T386I	386	Missense	central	0	yes	328.520	0.000	EPSD	COSMIC	271.430	Loss
CAMK_CAMKL_MARK_MARK2_ST	P10636	MAPT	Q7KZI7	MARK2	T386	D389N	389	Missense	distal	3	no	328.520	309.571	EPSD	COSMIC;GDSC;CCLE	271.430	Down-regulation
CAMK_CAMKL_MARK_MARK2_ST	P10636	MAPT	Q7KZI7	MARK2	S388	G385V	385	Missense	distal	-3	no	290.446	269.085	EPSD	COSMIC	271.430	Loss
CAMK_CAMKL_MARK_MARK2_ST	P10636	MAPT	Q7KZI7	MARK2	S388	T386I	386	Missense	proximal	-2	no	290.446	288.907	EPSD	COSMIC	271.430	Down-regulation
CAMK_CAMKL_MARK_MARK2_ST	P10636	MAPT	Q7KZI7	MARK2	S388	D389N	389	Missense	proximal	1	no	290.446	301.643	EPSD	COSMIC;GDSC;CCLE	271.430	Up-regulation
CAMK_CAMKL_MARK_MARK2_ST	P10636	MAPT	Q7KZI7	MARK2	S451	S447P	447	Missense	distal	-4	no	301.895	308.142	EPSD	COSMIC	271.430	Up-regulation
CAMK_CAMKL_MARK_MARK2_ST	P10636	MAPT	Q7KZI7	MARK2	S451	R448Q	448	Missense	distal	-3	no	301.895	199.853	EPSD	COSMIC	271.430	Loss
CAMK_CAMKL_MARK_MARK2_ST	P10636	MAPT	Q7KZI7	MARK2	S502	P506L	506	Missense	distal	4	no	166.273	294.852	EPSD	COSMIC	271.430	Gain
CAMK_CAMKL_MARK_MARK2_ST	P10636	MAPT	Q7KZI7	MARK2	S552	P550S	550	Missense	proximal	-2	no	297.605	299.532	EPSD	COSMIC	271.430	Up-regulation
CAMK_CAMKL_MARK_MARK2_ST	P10636	MAPT	Q7KZI7	MARK2	S552	R559C	559	Missense	distal	7	no	297.605	285.289	EPSD	COSMIC	271.430	Down-regulation
CAMK_CAMKL_MARK_MARK2_ST	P10636	MAPT	Q7KZI7	MARK2	S552	P553R	553	Missense	proximal	1	no	297.605	301.930	EPSD	COSMIC	271.430	Up-regulation
CAMK_CAMKL_MARK_MARK2_ST	P10636	MAPT	Q7KZI7	MARK2	S552	P553L	553	Missense	proximal	1	no	297.605	304.376	EPSD	COSMIC	271.430	Up-regulation
CAMK_CAMKL_MARK_MARK2_ST	P10636	MAPT	Q7KZI7	MARK2	S552	P549L	549	Missense	distal	-3	no	297.605	333.077	EPSD	COSMIC	271.430	Up-regulation
CAMK_CAMKL_MARK_MARK2_ST	P10636	MAPT	Q7KZI7	MARK2	S552	S555F	555	Missense	distal	3	no	297.605	291.298	EPSD	COSMIC	271.430	Down-regulation
CAMK_CAMKL_MARK_MARK2_ST	P10636	MAPT	Q7KZI7	MARK2	S552	P553Q	553	Missense	proximal	1	no	297.605	295.564	EPSD	COSMIC	271.430	Down-regulation
CAMK_CAMKL_MARK_MARK2_ST	P10636	MAPT	Q7KZI7	MARK2	S579	T580N	580	Missense	proximal	1	no	410.485	423.141	EPSD	COSMIC	271.430	Up-regulation
CAMK_CAMKL_MARK_MARK2_ST	P10636	MAPT	Q7KZI7	MARK2	S579	G578S	578	Missense	proximal	-1	no	410.485	409.138	EPSD	COSMIC	271.430	Down-regulation
CAMK_CAMKL_MARK_MARK2_ST	P10636	MAPT	Q7KZI7	MARK2	S610	N613D	613	Missense	distal	3	no	391.407	410.356	EPSD	COSMIC	271.430	Up-regulation
CAMK_CAMKL_MARK_MARK2_ST	P10636	MAPT	Q7KZI7	MARK2	S610	C608W	608	Missense	proximal	-2	no	391.407	386.608	EPSD	COSMIC	271.430	Down-regulation
CAMK_CAMKL_MARK_MARK2_ST	P10636	MAPT	Q7KZI7	MARK2	S610	S610L	610	Missense	central	0	yes	391.407	0.000	EPSD	COSMIC	271.430	Loss
CAMK_CAMKL_MARK_MARK2_ST	P10636	MAPT	Q7KZI7	MARK2	T636	S633N	633	Missense	distal	-3	no	266.181	295.137	EPSD	COSMIC	271.430	Gain
CAMK_CAMKL_MARK_MARK2_ST	P10636	MAPT	Q7KZI7	MARK2	S641	H647Y	647	Missense	distal	6	no	372.616	365.071	EPSD	COSMIC	271.430	Down-regulation
CAMK_CAMKL_MARK_MARK2_ST	P10636	MAPT	Q7KZI7	MARK2	S673	V680I	680	Missense	distal	7	no	347.016	339.843	EPSD	COSMIC	271.430	Down-regulation
CAMK_CAMKL_MARK_MARK2_ST	P10636	MAPT	Q7KZI7	MARK2	S673	S669L	669	Missense	distal	-4	no	347.016	340.221	EPSD	COSMIC	271.430	Down-regulation
CAMK_CAMKL_MARK_MARK2_ST	P10636	MAPT	Q7KZI7	MARK2	S673	R666K	666	Missense	distal	-7	no	347.016	347.078	EPSD	COSMIC	271.430	Up-regulation
CAMK_CAMKL_MARK_MARK2_ST	P10636	MAPT	Q7KZI7	MARK2	S673	S673F	673	Missense	central	0	yes	347.016	0.000	EPSD	COSMIC	271.430	Loss
CAMK_CAMKL_MARK_MARK2_ST	P10636	MAPT	Q7KZI7	MARK2	S673	K670N	670	Missense	distal	-3	no	347.016	315.101	EPSD	COSMIC	271.430	Down-regulation
CAMK_CAMKL_MARK_MARK2_ST	P10636	MAPT	Q7KZI7	MARK2	S673	L674Q	674	Missense	proximal	1	no	347.016	338.205	EPSD	COSMIC	271.430	Down-regulation
CAMK_CAMKL_MARK_MARK2_ST	P10636	MAPT	Q7KZI7	MARK2	T678	G683R	683	Missense	distal	5	no	268.087	288.456	EPSD	COSMIC;CCLE	271.430	Gain
CAMK_CAMKL_MARK_MARK2_ST	P10636	MAPT	Q7KZI7	MARK2	T678	S673F	673	Missense	distal	-5	no	268.087	274.931	EPSD	COSMIC	271.430	Gain
CAMK_CAMKL_MARK_MARK2_ST	P10636	MAPT	Q7KZI7	MARK2	T694	R696H	696	Missense	proximal	2	no	320.613	305.759	EPSD	COSMIC	271.430	Down-regulation
CAMK_CAMKL_MARK_MARK2_ST	P10636	MAPT	Q7KZI7	MARK2	T694	R696C	696	Missense	proximal	2	no	320.613	331.940	EPSD	COSMIC	271.430	Up-regulation
CAMK_CAMKL_MARK_MARK2_ST	P10636	MAPT	Q7KZI7	MARK2	T703	E708D	708	Missense	distal	5	no	264.348	279.041	EPSD	COSMIC	271.430	Gain
CAMK_CAMKL_MARK_MARK2_ST	P10636	MAPT	Q7KZI7	MARK2	T703	G706R	706	Missense	distal	3	no	264.348	282.160	EPSD	COSMIC	271.430	Gain
CAMK_CAMKL_MARK_MARK2_ST	P10636	MAPT	Q7KZI7	MARK2	T703	E708K	708	Missense	distal	5	no	264.348	286.350	EPSD	COSMIC	271.430	Gain
CAMK_CAMKL_MARK_MARK2_ST	P10636	MAPT	Q7KZI7	MARK2	S730	G732S	732	Missense	proximal	2	no	282.244	308.816	EPSD	COSMIC	271.430	Up-regulation
CAMK_CAMKL_MARK_MARK2_ST	P10636	MAPT	Q7KZI7	MARK2	S730	D735N	735	Missense	distal	5	no	282.244	289.138	EPSD	COSMIC	271.430	Up-regulation
CAMK_CAMKL_MARK_MARK2_ST	P10636	MAPT	Q7KZI7	MARK2	S730	G732C	732	Missense	proximal	2	no	282.244	300.021	EPSD	COSMIC	271.430	Up-regulation
CAMK_CAMKL_MARK_MARK2_ST	P10636	MAPT	Q7KZI7	MARK2	S730	R723W	723	Missense	distal	-7	no	282.244	282.420	EPSD	COSMIC	271.430	Up-regulation
CAMK_CAMKL_MARK_MARK2_ST	P10636	MAPT	Q7KZI7	MARK2	S730	V728M	728	Missense	proximal	-2	no	282.244	282.159	EPSD	COSMIC	271.430	Down-regulation
CAMK_CAMKL_MARK_MARK2_ST	P10636	MAPT	Q7KZI7	MARK2	S730	V728A	728	Missense	proximal	-2	no	282.244	281.590	EPSD	COSMIC	271.430	Down-regulation
CAMK_CAMKL_MARK_MARK2_ST	P10636	MAPT	Q7KZI7	MARK2	S733	G732S	732	Missense	proximal	-1	no	275.861	274.514	EPSD	COSMIC	271.430	Down-regulation
CAMK_CAMKL_MARK_MARK2_ST	P10636	MAPT	Q7KZI7	MARK2	S733	D735N	735	Missense	proximal	2	no	275.861	270.644	EPSD	COSMIC	271.430	Loss
CAMK_CAMKL_MARK_MARK2_ST	P10636	MAPT	Q7KZI7	MARK2	S733	G732C	732	Missense	proximal	-1	no	275.861	280.371	EPSD	COSMIC	271.430	Up-regulation
CAMK_CAMKL_MARK_MARK2_ST	P10636	MAPT	Q7KZI7	MARK2	S733	V728M	728	Missense	distal	-5	no	275.861	264.166	EPSD	COSMIC	271.430	Loss
CAMK_CAMKL_MARK_MARK2_ST	P10636	MAPT	Q7KZI7	MARK2	S733	V728A	728	Missense	distal	-5	no	275.861	262.723	EPSD	COSMIC	271.430	Loss
CAMK_CAMKL_MARK_MARK2_ST	Q9NQT8	KIF13B	Q7KZI7	MARK2	S202	S199L	199	Missense	distal	-3	no	251.756	286.370	EPSD	COSMIC	271.430	Gain
CAMK_CAMKL_MARK_MARK2_ST	Q9NQT8	KIF13B	Q7KZI7	MARK2	T209	S202F	202	Missense	distal	-7	no	283.117	283.219	EPSD	COSMIC;CCLE	271.430	Up-regulation
CAMK_CAMKL_MARK_MARK2_ST	Q9NQT8	KIF13B	Q7KZI7	MARK2	T209	A212T	212	Missense	distal	3	no	283.117	273.296	EPSD	COSMIC;GDSC;CCLE	271.430	Down-regulation
CAMK_CAMKL_MARK_MARK2_ST	Q9NQT8	KIF13B	Q7KZI7	MARK2	T233	D236N	236	Missense	distal	3	no	309.274	290.325	EPSD	COSMIC	271.430	Down-regulation
CAMK_CAMKL_MARK_MARK2_ST	Q9NQT8	KIF13B	Q7KZI7	MARK2	T233	T229A	229	Missense	distal	-4	no	309.274	296.388	EPSD	COSMIC	271.430	Down-regulation
CAMK_CAMKL_MARK_MARK2_ST	Q9NQT8	KIF13B	Q7KZI7	MARK2	T281	G284S	284	Missense	distal	3	no	266.050	273.938	EPSD	COSMIC	271.430	Gain
CAMK_CAMKL_MARK_MARK2_ST	Q9NQT8	KIF13B	Q7KZI7	MARK2	S1381	S1379R	1379	Missense	proximal	-2	no	362.657	361.461	EPSD;PhosphoSitePlus	COSMIC	271.430	Down-regulation
CAMK_CAMKL_MARK_MARK2_ST	Q9NQT8	KIF13B	Q7KZI7	MARK2	S1382	S1379R	1379	Missense	distal	-3	no	295.086	363.607	EPSD	COSMIC	271.430	Up-regulation
CAMK_CAMKL_MARK_MARK2_ST	Q9NQT8	KIF13B	Q7KZI7	MARK2	S1398	G1402S	1402	Missense	distal	4	no	302.139	214.478	EPSD	COSMIC	271.430	Loss
CAMK_CAMKL_MARK_MARK2_ST	Q9NQT8	KIF13B	Q7KZI7	MARK2	S1400	G1402S	1402	Missense	proximal	2	no	250.817	277.389	EPSD	COSMIC	271.430	Gain
CAMK_CAMKL_MARK_MARK2_ST	Q9NQT8	KIF13B	Q7KZI7	MARK2	S1410	T1417N	1417	Missense	distal	7	no	349.208	356.903	PhosphoSitePlus;EPSD	COSMIC	271.430	Up-regulation
CAMK_CAMKL_MARK_MARK2_ST	Q9NQT8	KIF13B	Q7KZI7	MARK2	T1418	T1417N	1417	Missense	proximal	-1	no	288.265	298.067	EPSD	COSMIC	271.430	Up-regulation
CAMK_CAMKL_MARK_MARK2_ST	Q9NQT8	KIF13B	Q7KZI7	MARK2	T1418	G1422R	1422	Missense	distal	4	no	288.265	227.908	EPSD	COSMIC	271.430	Loss
CAMK_CAMKL_MARK_MARK2_ST	Q9NQT8	KIF13B	Q7KZI7	MARK2	S1432	A1428T	1428	Missense	distal	-4	no	293.304	306.189	EPSD	COSMIC;GDSC;CCLE	271.430	Up-regulation
CAMK_CAMKL_MARK_MARK2_ST	Q9NQT8	KIF13B	Q7KZI7	MARK2	S1438	P1441L	1441	Missense	distal	3	no	333.142	333.772	EPSD	COSMIC	271.430	Up-regulation
CAMK_CAMKL_MARK_MARK2_ST	Q9NQT8	KIF13B	Q7KZI7	MARK2	S1444	P1441L	1441	Missense	distal	-3	no	254.536	290.008	EPSD	COSMIC	271.430	Gain
CAMK_CAMKL_MARK_MARK2_ST	Q9NQT8	KIF13B	Q7KZI7	MARK2	S1481	R1479W	1479	Missense	proximal	-2	no	298.714	296.567	EPSD	COSMIC;GDSC;CCLE	271.430	Down-regulation
CAMK_CAMKL_MARK_MARK2_ST	Q9NQT8	KIF13B	Q7KZI7	MARK2	T1779	P1773T	1773	Missense	distal	-6	no	276.596	277.520	EPSD	COSMIC	271.430	Up-regulation
CAMK_CAMKL_MARK_MARK2_ST	Q9NQT8	KIF13B	Q7KZI7	MARK2	T1779	R1782W	1782	Missense	distal	3	no	276.596	241.527	EPSD	COSMIC	271.430	Loss
CAMK_CAMKL_MARK_MARK2_ST	Q9NQT8	KIF13B	Q7KZI7	MARK2	S1797	S1795L	1795	Missense	proximal	-2	no	315.929	316.813	EPSD	COSMIC;CCLE	271.430	Up-regulation
CAMK_CAMKL_MARK_MARK2_ST	Q7L804	RAB11FIP2	Q7KZI7	MARK2	S150	D153G	153	Missense	distal	3	no	287.118	230.379	EPSD	COSMIC	271.430	Loss
CAMK_CAMKL_MARK_MARK2_ST	Q7L804	RAB11FIP2	Q7KZI7	MARK2	S150	F152L	152	Missense	proximal	2	no	287.118	286.173	EPSD	COSMIC	271.430	Down-regulation
CAMK_CAMKL_MARK_MARK2_ST	Q7L804	RAB11FIP2	Q7KZI7	MARK2	S150	S155A	155	Missense	distal	5	no	287.118	274.260	EPSD	COSMIC	271.430	Down-regulation
CAMK_CAMKL_MARK_MARK2_ST	Q7L804	RAB11FIP2	Q7KZI7	MARK2	S162	R161G	161	Missense	proximal	-1	no	292.247	295.088	EPSD	COSMIC	271.430	Up-regulation
CAMK_CAMKL_MARK_MARK2_ST	Q7L804	RAB11FIP2	Q7KZI7	MARK2	S162	S155A	155	Missense	distal	-7	no	292.247	292.387	EPSD	COSMIC	271.430	Up-regulation
CAMK_CAMKL_MARK_MARK2_ST	Q7L804	RAB11FIP2	Q7KZI7	MARK2	S227	S223L	223	Missense	distal	-4	no	390.699	383.904	PhosphoSitePlus	COSMIC;CCLE	271.430	Down-regulation
CAMK_CAMKL_MARK_MARK2_ST	Q7L804	RAB11FIP2	Q7KZI7	MARK2	S238	M236T	236	Missense	proximal	-2	no	280.824	280.805	EPSD	COSMIC	271.430	Down-regulation
CAMK_CAMKL_MARK_MARK2_ST	Q7L804	RAB11FIP2	Q7KZI7	MARK2	S288	D287Y	287	Missense	proximal	-1	no	289.458	279.248	EPSD	COSMIC	271.430	Down-regulation
CAMK_CAMKL_MARK_MARK2_ST	Q7L804	RAB11FIP2	Q7KZI7	MARK2	S288	D287G	287	Missense	proximal	-1	no	289.458	294.948	EPSD	COSMIC	271.430	Up-regulation
CAMK_CAMKL_MARK_MARK2_ST	Q7L804	RAB11FIP2	Q7KZI7	MARK2	T317	R320K	320	Missense	distal	3	no	284.180	278.882	EPSD	COSMIC	271.430	Down-regulation
CAMK_CAMKL_MARK_MARK2_ST	Q7L804	RAB11FIP2	Q7KZI7	MARK2	T317	F315L	315	Missense	proximal	-2	no	284.180	287.215	EPSD	COSMIC	271.430	Up-regulation
CAMK_CAMKL_MARK_MARK2_ST	Q7L804	RAB11FIP2	Q7KZI7	MARK2	T317	A316E	316	Missense	proximal	-1	no	284.180	283.630	EPSD	COSMIC	271.430	Down-regulation
CAMK_CAMKL_MARK_MARK2_ST	Q7L804	RAB11FIP2	Q7KZI7	MARK2	S380	K387N	387	Missense	distal	7	no	300.125	304.885	EPSD	COSMIC	271.430	Up-regulation
CAMK_CAMKL_MARK_MARK2_ST	Q7L804	RAB11FIP2	Q7KZI7	MARK2	S382	K387N	387	Missense	distal	5	no	340.659	340.243	EPSD	COSMIC	271.430	Down-regulation
CAMK_CAMKL_MARK_MARK2_ST	Q99689	FEZ1	Q7KZI7	MARK2	S316	G319S	319	Missense	distal	3	no	292.063	299.951	EPSD	COSMIC	271.430	Up-regulation
CAMK_CAMKL_MARK_MARK2_ST	P78352	DLG4	Q7KZI7	MARK2	S73	A80T	80	Missense	distal	7	no	258.515	271.807	EPSD	COSMIC	271.430	Gain
CAMK_CAMKL_MARK_MARK2_ST	P78352	DLG4	Q7KZI7	MARK2	S295	S290R	290	Missense	distal	-5	no	312.097	319.746	EPSD	COSMIC	271.430	Up-regulation
CAMK_CAMKL_MARK_MARK2_ST	P78352	DLG4	Q7KZI7	MARK2	S295	S295R	295	Missense	central	0	yes	312.097	0.000	EPSD	COSMIC	271.430	Loss
CAMK_CAMKL_MARK_MARK2_ST	P78352	DLG4	Q7KZI7	MARK2	S295	P296L	296	Missense	proximal	1	no	312.097	318.868	EPSD	COSMIC	271.430	Up-regulation
CAMK_CAMKL_MARK_MARK2_ST	P78352	DLG4	Q7KZI7	MARK2	S295	R292W	292	Missense	distal	-3	no	312.097	164.556	EPSD	COSMIC	271.430	Loss
CAMK_CAMKL_MARK_MARK2_ST	P78352	DLG4	Q7KZI7	MARK2	S295	S290F	290	Missense	distal	-5	no	312.097	318.940	EPSD	COSMIC	271.430	Up-regulation
CAMK_CAMKL_MARK_MARK2_ST	P78352	DLG4	Q7KZI7	MARK2	S295	R292Q	292	Missense	distal	-3	no	312.097	210.054	EPSD	COSMIC	271.430	Loss
CAMK_CAMKL_MARK_MARK2_ST	P78352	DLG4	Q7KZI7	MARK2	S295	R293H	293	Missense	proximal	-2	no	312.097	311.866	EPSD	COSMIC;CCLE	271.430	Down-regulation
CAMK_CAMKL_MARK_MARK2_ST	P78352	DLG4	Q7KZI7	MARK2	S295	P296A	296	Missense	proximal	1	no	312.097	317.491	EPSD	COSMIC	271.430	Up-regulation
CAMK_CAMKL_MARK_MARK2_ST	P78352	DLG4	Q7KZI7	MARK2	S295	Y294F	294	Missense	proximal	-1	no	312.097	324.973	EPSD	COSMIC	271.430	Up-regulation
CAMK_CAMKL_MARK_MARK2_ST	P78352	DLG4	Q7KZI7	MARK2	S295	R293C	293	Missense	proximal	-2	no	312.097	314.749	EPSD	COSMIC	271.430	Up-regulation
CAMK_CAMKL_MARK_MARK2_ST	P78352	DLG4	Q7KZI7	MARK2	T442	D440Y	440	Missense	proximal	-2	no	314.949	314.394	EPSD	COSMIC	271.430	Down-regulation
CAMK_CAMKL_MARK_MARK2_ST	P78352	DLG4	Q7KZI7	MARK2	T442	L436R	436	Missense	distal	-6	no	314.949	313.332	EPSD	COSMIC	271.430	Down-regulation
CAMK_CAMKL_MARK_MARK2_ST	P78352	DLG4	Q7KZI7	MARK2	T442	A435V	435	Missense	distal	-7	no	314.949	314.885	EPSD	COSMIC	271.430	Down-regulation
CAMK_CAMKL_MARK_MARK2_ST	P78352	DLG4	Q7KZI7	MARK2	T442	D440G	440	Missense	proximal	-2	no	314.949	315.081	EPSD	COSMIC	271.430	Up-regulation
CAMK_CAMKL_MARK_MARK2_ST	P78352	DLG4	Q7KZI7	MARK2	S478	D483G	483	Missense	distal	5	no	325.676	309.110	EPSD	COSMIC	271.430	Down-regulation
CAMK_CAMKL_MARK_MARK2_ST	P78352	DLG4	Q7KZI7	MARK2	S478	W471R	471	Missense	distal	-7	no	325.676	325.501	EPSD	COSMIC	271.430	Down-regulation
CAMK_CAMKL_MARK_MARK2_ST	P78352	DLG4	Q7KZI7	MARK2	S478	D484N	484	Missense	distal	6	no	325.676	330.493	EPSD	COSMIC	271.430	Up-regulation
CAMK_CAMKL_MARK_MARK2_ST	P78352	DLG4	Q7KZI7	MARK2	S478	S480C	480	Missense	proximal	2	no	325.676	316.881	EPSD	COSMIC	271.430	Down-regulation
CAMK_CAMKL_MARK_MARK2_ST	P78352	DLG4	Q7KZI7	MARK2	S478	D483N	483	Missense	distal	5	no	325.676	332.569	EPSD	COSMIC	271.430	Up-regulation
CAMK_CAMKL_MARK_MARK2_ST	P78352	DLG4	Q7KZI7	MARK2	S478	V476G	476	Missense	proximal	-2	no	325.676	325.092	EPSD	COSMIC	271.430	Down-regulation
CAMK_CAMKL_MARK_MARK2_ST	P78352	DLG4	Q7KZI7	MARK2	S480	D483G	483	Missense	distal	3	no	339.005	282.266	EPSD	COSMIC	271.430	Down-regulation
CAMK_CAMKL_MARK_MARK2_ST	P78352	DLG4	Q7KZI7	MARK2	S480	D484N	484	Missense	distal	4	no	339.005	363.504	EPSD	COSMIC	271.430	Up-regulation
CAMK_CAMKL_MARK_MARK2_ST	P78352	DLG4	Q7KZI7	MARK2	S480	S480C	480	Missense	central	0	yes	339.005	0.000	EPSD	COSMIC	271.430	Loss
CAMK_CAMKL_MARK_MARK2_ST	P78352	DLG4	Q7KZI7	MARK2	S480	D483N	483	Missense	distal	3	no	339.005	320.056	EPSD	COSMIC	271.430	Down-regulation
CAMK_CAMKL_MARK_MARK2_ST	P78352	DLG4	Q7KZI7	MARK2	S480	V476G	476	Missense	distal	-4	no	339.005	350.116	EPSD	COSMIC	271.430	Up-regulation
CAMK_CAMKL_MARK_MARK2_ST	P78352	DLG4	Q7KZI7	MARK2	S561	E554K	554	Missense	distal	-7	no	344.237	344.191	PhosphoSitePlus	COSMIC	271.430	Down-regulation
CAMK_CAMKL_MARK_MARK2_ST	P78352	DLG4	Q7KZI7	MARK2	S561	T567K	567	Missense	distal	6	no	344.237	347.052	PhosphoSitePlus	COSMIC	271.430	Up-regulation
CAMK_CAMKL_MARK_MARK2_ST	P78352	DLG4	Q7KZI7	MARK2	S561	H565N	565	Missense	distal	4	no	344.237	363.229	PhosphoSitePlus	COSMIC	271.430	Up-regulation
CAMK_CAMKL_MARK_MARK2_ST	P78352	DLG4	Q7KZI7	MARK2	S561	T566M	566	Missense	distal	5	no	344.237	340.897	PhosphoSitePlus	COSMIC;CCLE	271.430	Down-regulation
CAMK_CAMKL_MARK_MARK2_ST	P78352	DLG4	Q7KZI7	MARK2	S561	D557Y	557	Missense	distal	-4	no	344.237	334.480	PhosphoSitePlus	COSMIC	271.430	Down-regulation
CAMK_CAMKL_MARK_MARK2_ST	P78352	DLG4	Q7KZI7	MARK2	S561	K558R	558	Missense	distal	-3	no	344.237	351.887	PhosphoSitePlus	COSMIC	271.430	Up-regulation
CAMK_CAMKL_MARK_MARK2_ST	P78352	DLG4	Q7KZI7	MARK2	S561	C562R	562	Missense	proximal	1	no	344.237	346.106	PhosphoSitePlus	COSMIC	271.430	Up-regulation
CAMK_CAMKL_MARK_MARK2_ST	P78352	DLG4	Q7KZI7	MARK2	S561	D557E	557	Missense	distal	-4	no	344.237	339.788	PhosphoSitePlus	COSMIC	271.430	Down-regulation
CAMK_CAMKL_MARK_MARK2_ST	P78352	DLG4	Q7KZI7	MARK2	S561	R568W	568	Missense	distal	7	no	344.237	308.565	PhosphoSitePlus	COSMIC;CCLE	271.430	Down-regulation
CAMK_CAMKL_MARK_MARK2_ST	P78352	DLG4	Q7KZI7	MARK2	S654	R651H	651	Missense	distal	-3	no	340.206	317.226	EPSD	COSMIC	271.430	Down-regulation
CAMK_CAMKL_MARK_MARK2_ST	P78352	DLG4	Q7KZI7	MARK2	S654	R651C	651	Missense	distal	-3	no	340.206	247.399	EPSD	COSMIC	271.430	Loss
CAMK_CAMKL_MARK_MARK2_ST	P78352	DLG4	Q7KZI7	MARK2	S654	R653C	653	Missense	proximal	-1	no	340.206	347.558	EPSD	COSMIC	271.430	Up-regulation
CAMK_CAMKL_MARK_MARK2_ST	P78352	DLG4	Q7KZI7	MARK2	S654	V658A	658	Missense	distal	4	no	340.206	329.567	EPSD	COSMIC	271.430	Down-regulation
CAMK_CAMKL_MARK_MARK2_ST	P78352	DLG4	Q7KZI7	MARK2	S654	P652L	652	Missense	proximal	-2	no	340.206	343.018	EPSD	COSMIC	271.430	Up-regulation
CAMK_CAMKL_MARK_MARK2_ST	Q9UQB8	BAIAP2	Q7KZI7	MARK2	S259	S263F	263	Missense	distal	4	no	281.512	335.537	EPSD	COSMIC	271.430	Up-regulation
CAMK_CAMKL_MARK_MARK2_ST	Q9UQB8	BAIAP2	Q7KZI7	MARK2	S259	L265P	265	Missense	distal	6	no	281.512	266.980	EPSD	COSMIC	271.430	Loss
CAMK_CAMKL_MARK_MARK2_ST	Q9UQB8	BAIAP2	Q7KZI7	MARK2	S261	S263F	263	Missense	proximal	2	no	297.356	265.182	EPSD	COSMIC	271.430	Loss
CAMK_CAMKL_MARK_MARK2_ST	Q9UQB8	BAIAP2	Q7KZI7	MARK2	S261	L265P	265	Missense	distal	4	no	297.356	168.777	EPSD	COSMIC	271.430	Loss
CAMK_CAMKL_MARK_MARK2_ST	Q9UQB8	BAIAP2	Q7KZI7	MARK2	S263	L265P	265	Missense	proximal	2	no	260.710	279.105	EPSD	COSMIC	271.430	Gain
CAMK_CAMKL_MARK_MARK2_ST	Q9UQB8	BAIAP2	Q7KZI7	MARK2	T303	Y310H	310	Missense	distal	7	no	293.838	297.367	EPSD	COSMIC	271.430	Up-regulation
CAMK_CAMKL_MARK_MARK2_ST	Q9UQB8	BAIAP2	Q7KZI7	MARK2	T303	P305L	305	Missense	proximal	2	no	293.838	275.442	EPSD	COSMIC	271.430	Down-regulation
CAMK_CAMKL_MARK_MARK2_ST	Q9UQB8	BAIAP2	Q7KZI7	MARK2	T303	P305S	305	Missense	proximal	2	no	293.838	308.561	EPSD	COSMIC	271.430	Up-regulation
CAMK_CAMKL_MARK_MARK2_ST	Q9UQB8	BAIAP2	Q7KZI7	MARK2	S329	S323F	323	Missense	distal	-6	no	286.401	285.613	EPSD	COSMIC	271.430	Down-regulation
CAMK_CAMKL_MARK_MARK2_ST	Q9UQB8	BAIAP2	Q7KZI7	MARK2	S329	S331N	331	Missense	proximal	2	no	286.401	275.320	EPSD	COSMIC;GDSC;CCLE	271.430	Down-regulation
CAMK_CAMKL_MARK_MARK2_ST	Q9UQB8	BAIAP2	Q7KZI7	MARK2	S336	S331N	331	Missense	distal	-5	no	279.004	299.011	EPSD	COSMIC;GDSC;CCLE	271.430	Up-regulation
CAMK_CAMKL_MARK_MARK2_ST	Q9UQB8	BAIAP2	Q7KZI7	MARK2	S336	P342H	342	Missense	distal	6	no	279.004	285.250	EPSD	COSMIC	271.430	Up-regulation
CAMK_CAMKL_MARK_MARK2_ST	Q9UQB8	BAIAP2	Q7KZI7	MARK2	S336	V343M	343	Missense	distal	7	no	279.004	265.046	EPSD	COSMIC	271.430	Loss
CAMK_CAMKL_MARK_MARK2_ST	Q9UQB8	BAIAP2	Q7KZI7	MARK2	S336	P342S	342	Missense	distal	6	no	279.004	280.446	EPSD	COSMIC	271.430	Up-regulation
CAMK_CAMKL_MARK_MARK2_ST	Q9UQB8	BAIAP2	Q7KZI7	MARK2	S338	P342H	342	Missense	distal	4	no	201.319	312.470	EPSD	COSMIC	271.430	Gain
CAMK_CAMKL_MARK_MARK2_ST	Q9UQB8	BAIAP2	Q7KZI7	MARK2	T340	R344G	344	Missense	distal	4	no	278.770	339.126	EPSD	COSMIC;GDSC;CCLE	271.430	Up-regulation
CAMK_CAMKL_MARK_MARK2_ST	Q9UQB8	BAIAP2	Q7KZI7	MARK2	T340	P342H	342	Missense	proximal	2	no	278.770	258.518	EPSD	COSMIC	271.430	Loss
CAMK_CAMKL_MARK_MARK2_ST	Q9UQB8	BAIAP2	Q7KZI7	MARK2	T340	V343M	343	Missense	distal	3	no	278.770	249.519	EPSD	COSMIC	271.430	Loss
CAMK_CAMKL_MARK_MARK2_ST	Q9UQB8	BAIAP2	Q7KZI7	MARK2	T340	P342S	342	Missense	proximal	2	no	278.770	293.494	EPSD	COSMIC	271.430	Up-regulation
CAMK_CAMKL_MARK_MARK2_ST	Q9UQB8	BAIAP2	Q7KZI7	MARK2	T355	A354T	354	Missense	proximal	-1	no	286.952	281.949	EPSD	COSMIC	271.430	Down-regulation
CAMK_CAMKL_MARK_MARK2_ST	Q9UQB8	BAIAP2	Q7KZI7	MARK2	T356	A354T	354	Missense	proximal	-2	no	278.310	278.861	EPSD	COSMIC	271.430	Up-regulation
CAMK_CAMKL_MARK_MARK2_ST	Q9UQB8	BAIAP2	Q7KZI7	MARK2	T356	R363C	363	Missense	distal	7	no	278.310	265.995	EPSD	COSMIC	271.430	Loss
CAMK_CAMKL_MARK_MARK2_ST	Q9UQB8	BAIAP2	Q7KZI7	MARK2	S364	L371M	371	Missense	distal	7	no	305.903	298.245	EPSD	COSMIC	271.430	Down-regulation
CAMK_CAMKL_MARK_MARK2_ST	Q9UQB8	BAIAP2	Q7KZI7	MARK2	S364	A369D	369	Missense	distal	5	no	305.903	316.688	EPSD	COSMIC	271.430	Up-regulation
CAMK_CAMKL_MARK_MARK2_ST	Q9UQB8	BAIAP2	Q7KZI7	MARK2	S364	R363C	363	Missense	proximal	-1	no	305.903	313.255	EPSD	COSMIC	271.430	Up-regulation
CAMK_CAMKL_MARK_MARK2_ST	Q9UQB8	BAIAP2	Q7KZI7	MARK2	S364	S364N	364	Missense	central	0	yes	305.903	0.000	EPSD	COSMIC	271.430	Loss
CAMK_CAMKL_MARK_MARK2_ST	Q9UQB8	BAIAP2	Q7KZI7	MARK2	S366	L371M	371	Missense	distal	5	no	364.709	353.109	PhosphoSitePlus	COSMIC	271.430	Down-regulation
CAMK_CAMKL_MARK_MARK2_ST	Q9UQB8	BAIAP2	Q7KZI7	MARK2	S366	A369D	369	Missense	distal	3	no	364.709	412.652	PhosphoSitePlus	COSMIC	271.430	Up-regulation
CAMK_CAMKL_MARK_MARK2_ST	Q9UQB8	BAIAP2	Q7KZI7	MARK2	S366	R373C	373	Missense	distal	7	no	364.709	352.394	PhosphoSitePlus	COSMIC	271.430	Down-regulation
CAMK_CAMKL_MARK_MARK2_ST	Q9UQB8	BAIAP2	Q7KZI7	MARK2	S366	R363C	363	Missense	distal	-3	no	364.709	271.902	PhosphoSitePlus	COSMIC	271.430	Down-regulation
CAMK_CAMKL_MARK_MARK2_ST	Q9UQB8	BAIAP2	Q7KZI7	MARK2	S366	S364N	364	Missense	proximal	-2	no	364.709	365.251	PhosphoSitePlus	COSMIC	271.430	Up-regulation
CAMK_CAMKL_MARK_MARK2_ST	Q9UQB8	BAIAP2	Q7KZI7	MARK2	S454	D460A	460	Missense	distal	6	no	365.819	359.392	EPSD	COSMIC	271.430	Down-regulation
CAMK_CAMKL_MARK_MARK2_ST	Q9UQB8	BAIAP2	Q7KZI7	MARK2	S509	R512K	512	Missense	distal	3	no	315.421	310.123	EPSD	COSMIC	271.430	Down-regulation
CAMK_CAMKL_MARK_MARK2_ST	Q9UQB8	BAIAP2	Q7KZI7	MARK2	S509	A516D	516	Missense	distal	7	no	315.421	319.852	EPSD	COSMIC	271.430	Up-regulation
CAMK_CAMKL_MARK_MARK2_ST	Q9UQB8	BAIAP2	Q7KZI7	MARK2	S509	D503N	503	Missense	distal	-6	no	315.421	315.394	EPSD	COSMIC	271.430	Down-regulation
CAMK_CAMKL_MARK_MARK2_ST	P46939	UTRN	Q7KZI7	MARK2	S10	K3T	3	Missense	distal	-7	no	390.586	390.593	EPSD	COSMIC	271.430	Up-regulation
CAMK_CAMKL_MARK_MARK2_ST	P46939	UTRN	Q7KZI7	MARK2	S10	A9G	9	Missense	proximal	-1	no	390.586	400.680	EPSD	COSMIC	271.430	Up-regulation
CAMK_CAMKL_MARK_MARK2_ST	P46939	UTRN	Q7KZI7	MARK2	S623	R627I	627	Missense	distal	4	no	255.049	289.191	EPSD	COSMIC	271.430	Gain
CAMK_CAMKL_MARK_MARK2_ST	P46939	UTRN	Q7KZI7	MARK2	S631	Q637E	637	Missense	distal	6	no	271.051	278.523	EPSD	COSMIC	271.430	Gain
CAMK_CAMKL_MARK_MARK2_ST	P46939	UTRN	Q7KZI7	MARK2	S933	A930T	930	Missense	distal	-3	no	296.215	324.559	EPSD	COSMIC	271.430	Up-regulation
CAMK_CAMKL_MARK_MARK2_ST	P46939	UTRN	Q7KZI7	MARK2	S1005	S1005F	1005	Missense	central	0	yes	310.427	0.000	EPSD	COSMIC	271.430	Loss
CAMK_CAMKL_MARK_MARK2_ST	P46939	UTRN	Q7KZI7	MARK2	S1258	M1256R	1256	Missense	proximal	-2	no	361.317	362.144	PhosphoSitePlus	COSMIC	271.430	Up-regulation
CAMK_CAMKL_MARK_MARK2_ST	P46939	UTRN	Q7KZI7	MARK2	S1258	E1260D	1260	Missense	proximal	2	no	361.317	373.883	PhosphoSitePlus	COSMIC	271.430	Up-regulation
CAMK_CAMKL_MARK_MARK2_ST	P46939	UTRN	Q7KZI7	MARK2	S1258	R1255Q	1255	Missense	distal	-3	no	361.317	259.274	PhosphoSitePlus	COSMIC	271.430	Loss
CAMK_CAMKL_MARK_MARK2_ST	P46939	UTRN	Q7KZI7	MARK2	T1361	D1357Y	1357	Missense	distal	-4	no	303.654	293.897	EPSD	COSMIC	271.430	Down-regulation
CAMK_CAMKL_MARK_MARK2_ST	P46939	UTRN	Q7KZI7	MARK2	S1695	R1692H	1692	Missense	distal	-3	no	306.864	283.885	EPSD	COSMIC	271.430	Down-regulation
CAMK_CAMKL_MARK_MARK2_ST	P46939	UTRN	Q7KZI7	MARK2	S1746	I1751V	1751	Missense	distal	5	no	282.605	301.840	EPSD	COSMIC	271.430	Up-regulation
CAMK_CAMKL_MARK_MARK2_ST	P46939	UTRN	Q7KZI7	MARK2	S1746	Q1753P	1753	Missense	distal	7	no	282.605	295.081	EPSD	COSMIC	271.430	Up-regulation
CAMK_CAMKL_MARK_MARK2_ST	P46939	UTRN	Q7KZI7	MARK2	S1796	D1803N	1803	Missense	distal	7	no	269.882	286.439	EPSD	COSMIC	271.430	Gain
CAMK_CAMKL_MARK_MARK2_ST	P46939	UTRN	Q7KZI7	MARK2	T2255	E2261Q	2261	Missense	distal	6	no	272.616	265.143	EPSD	COSMIC	271.430	Loss
CAMK_CAMKL_MARK_MARK2_ST	P46939	UTRN	Q7KZI7	MARK2	T2255	L2249P	2249	Missense	distal	-6	no	272.616	270.406	EPSD	COSMIC	271.430	Loss
CAMK_CAMKL_MARK_MARK2_ST	P46939	UTRN	Q7KZI7	MARK2	S2567	W2574R	2574	Missense	distal	7	no	286.958	322.630	EPSD	COSMIC	271.430	Up-regulation
CAMK_CAMKL_MARK_MARK2_ST	P46939	UTRN	Q7KZI7	MARK2	S2567	R2563G	2563	Missense	distal	-4	no	286.958	285.116	EPSD	COSMIC	271.430	Down-regulation
CAMK_CAMKL_MARK_MARK2_ST	P46939	UTRN	Q7KZI7	MARK2	S2567	M2566L	2566	Missense	proximal	-1	no	286.958	313.778	EPSD	COSMIC	271.430	Up-regulation
CAMK_CAMKL_MARK_MARK2_ST	P46939	UTRN	Q7KZI7	MARK2	S2666	K2669I	2669	Missense	distal	3	no	315.156	340.421	EPSD	COSMIC	271.430	Up-regulation
CAMK_CAMKL_MARK_MARK2_ST	P46939	UTRN	Q7KZI7	MARK2	S2666	R2662H	2662	Missense	distal	-4	no	315.156	301.241	EPSD	COSMIC	271.430	Down-regulation
CAMK_CAMKL_MARK_MARK2_ST	P46939	UTRN	Q7KZI7	MARK2	S2666	M2661I	2661	Missense	distal	-5	no	315.156	320.062	EPSD	COSMIC	271.430	Up-regulation
CAMK_CAMKL_MARK_MARK2_ST	P46939	UTRN	Q7KZI7	MARK2	S2851	E2847K	2847	Missense	distal	-4	no	305.310	305.576	EPSD	COSMIC;CCLE	271.430	Up-regulation
CAMK_CAMKL_MARK_MARK2_ST	P46939	UTRN	Q7KZI7	MARK2	S2851	D2854Y	2854	Missense	distal	3	no	305.310	250.012	EPSD	COSMIC	271.430	Loss
CAMK_CAMKL_MARK_MARK2_ST	Q9UQL6	HDAC5	Q7KZI7	MARK2	S16	L20M	20	Missense	distal	4	no	371.604	311.154	EPSD	COSMIC	271.430	Down-regulation
CAMK_CAMKL_MARK_MARK2_ST	Q9UQL6	HDAC5	Q7KZI7	MARK2	S16	R13W	13	Missense	distal	-3	no	371.604	224.064	EPSD	COSMIC	271.430	Loss
CAMK_CAMKL_MARK_MARK2_ST	Q9UQL6	HDAC5	Q7KZI7	MARK2	S16	L17F	17	Missense	proximal	1	no	371.604	364.094	EPSD	COSMIC	271.430	Down-regulation
CAMK_CAMKL_MARK_MARK2_ST	Q9UQL6	HDAC5	Q7KZI7	MARK2	S16	E18Q	18	Missense	proximal	2	no	371.604	352.611	EPSD	COSMIC	271.430	Down-regulation
CAMK_CAMKL_MARK_MARK2_ST	Q9UQL6	HDAC5	Q7KZI7	MARK2	S16	G12R	12	Missense	distal	-4	no	371.604	373.446	EPSD	COSMIC	271.430	Up-regulation
CAMK_CAMKL_MARK_MARK2_ST	Q9UQL6	HDAC5	Q7KZI7	MARK2	S53	R60W	60	Missense	distal	7	no	296.102	260.429	EPSD	COSMIC	271.430	Loss
CAMK_CAMKL_MARK_MARK2_ST	Q9UQL6	HDAC5	Q7KZI7	MARK2	S53	P54S	54	Missense	proximal	1	no	296.102	298.384	EPSD	COSMIC	271.430	Up-regulation
CAMK_CAMKL_MARK_MARK2_ST	Q9UQL6	HDAC5	Q7KZI7	MARK2	S53	R60L	60	Missense	distal	7	no	296.102	294.962	EPSD	COSMIC	271.430	Down-regulation
CAMK_CAMKL_MARK_MARK2_ST	Q9UQL6	HDAC5	Q7KZI7	MARK2	S53	G51E	51	Missense	proximal	-2	no	296.102	296.688	EPSD	COSMIC	271.430	Up-regulation
CAMK_CAMKL_MARK_MARK2_ST	Q9UQL6	HDAC5	Q7KZI7	MARK2	S55	R60W	60	Missense	distal	5	no	277.288	251.667	EPSD	COSMIC	271.430	Loss
CAMK_CAMKL_MARK_MARK2_ST	Q9UQL6	HDAC5	Q7KZI7	MARK2	S55	P54S	54	Missense	proximal	-1	no	277.288	288.490	EPSD	COSMIC	271.430	Up-regulation
CAMK_CAMKL_MARK_MARK2_ST	Q9UQL6	HDAC5	Q7KZI7	MARK2	S55	R60L	60	Missense	distal	5	no	277.288	283.071	EPSD	COSMIC	271.430	Up-regulation
CAMK_CAMKL_MARK_MARK2_ST	Q9UQL6	HDAC5	Q7KZI7	MARK2	S55	G51E	51	Missense	distal	-4	no	277.288	276.496	EPSD	COSMIC	271.430	Down-regulation
CAMK_CAMKL_MARK_MARK2_ST	Q9UQL6	HDAC5	Q7KZI7	MARK2	S229	G230A	230	Missense	proximal	1	no	274.524	281.088	EPSD	COSMIC	271.430	Up-regulation
CAMK_CAMKL_MARK_MARK2_ST	Q9UQL6	HDAC5	Q7KZI7	MARK2	S229	P232L	232	Missense	distal	3	no	274.524	275.153	EPSD	COSMIC	271.430	Up-regulation
CAMK_CAMKL_MARK_MARK2_ST	Q9UQL6	HDAC5	Q7KZI7	MARK2	S229	S224R	224	Missense	distal	-5	no	274.524	282.173	EPSD	COSMIC	271.430	Up-regulation
CAMK_CAMKL_MARK_MARK2_ST	Q9UQL6	HDAC5	Q7KZI7	MARK2	S229	G230R	230	Missense	proximal	1	no	274.524	280.020	EPSD	COSMIC;CCLE	271.430	Up-regulation
CAMK_CAMKL_MARK_MARK2_ST	Q9UQL6	HDAC5	Q7KZI7	MARK2	S229	G230D	230	Missense	proximal	1	no	274.524	280.764	EPSD	COSMIC;CCLE	271.430	Up-regulation
CAMK_CAMKL_MARK_MARK2_ST	Q9UQL6	HDAC5	Q7KZI7	MARK2	S229	P236S	236	Missense	distal	7	no	274.524	268.592	EPSD	COSMIC	271.430	Loss
CAMK_CAMKL_MARK_MARK2_ST	Q9UQL6	HDAC5	Q7KZI7	MARK2	S229	G230S	230	Missense	proximal	1	no	274.524	277.976	EPSD	COSMIC	271.430	Up-regulation
CAMK_CAMKL_MARK_MARK2_ST	Q9UQL6	HDAC5	Q7KZI7	MARK2	S229	P232T	232	Missense	distal	3	no	274.524	243.535	EPSD	COSMIC	271.430	Loss
CAMK_CAMKL_MARK_MARK2_ST	Q9UQL6	HDAC5	Q7KZI7	MARK2	S259	R255C	255	Missense	distal	-4	no	399.581	411.118	PhosphoSitePlus	COSMIC	271.430	Up-regulation
CAMK_CAMKL_MARK_MARK2_ST	Q9UQL6	HDAC5	Q7KZI7	MARK2	S259	R266C	266	Missense	distal	7	no	399.581	387.266	PhosphoSitePlus	COSMIC	271.430	Down-regulation
CAMK_CAMKL_MARK_MARK2_ST	Q9UQL6	HDAC5	Q7KZI7	MARK2	S259	R266H	266	Missense	distal	7	no	399.581	390.586	PhosphoSitePlus	COSMIC	271.430	Down-regulation
CAMK_CAMKL_MARK_MARK2_ST	Q9UQL6	HDAC5	Q7KZI7	MARK2	S278	R284C	284	Missense	distal	6	no	282.841	283.092	EPSD	COSMIC	271.430	Up-regulation
CAMK_CAMKL_MARK_MARK2_ST	Q9UQL6	HDAC5	Q7KZI7	MARK2	S278	S279N	279	Missense	proximal	1	no	282.841	296.825	EPSD	COSMIC	271.430	Up-regulation
CAMK_CAMKL_MARK_MARK2_ST	Q9UQL6	HDAC5	Q7KZI7	MARK2	S278	R284S	284	Missense	distal	6	no	282.841	277.789	EPSD	COSMIC	271.430	Down-regulation
CAMK_CAMKL_MARK_MARK2_ST	Q9UQL6	HDAC5	Q7KZI7	MARK2	S279	R284C	284	Missense	distal	5	no	276.626	262.163	EPSD	COSMIC	271.430	Loss
CAMK_CAMKL_MARK_MARK2_ST	Q9UQL6	HDAC5	Q7KZI7	MARK2	S279	S279N	279	Missense	central	0	yes	276.626	0.000	EPSD	COSMIC	271.430	Loss
CAMK_CAMKL_MARK_MARK2_ST	Q9UQL6	HDAC5	Q7KZI7	MARK2	S279	R284S	284	Missense	distal	5	no	276.626	274.897	EPSD	COSMIC	271.430	Down-regulation
CAMK_CAMKL_MARK_MARK2_ST	Q9UQL6	HDAC5	Q7KZI7	MARK2	S611	E608K	608	Missense	distal	-3	no	160.641	273.166	EPSD	COSMIC	271.430	Gain
CAMK_CAMKL_MARK_MARK2_ST	Q9UQL6	HDAC5	Q7KZI7	MARK2	S661	T659S	659	Missense	proximal	-2	no	271.278	273.321	EPSD	COSMIC	271.430	Gain
CAMK_CAMKL_MARK_MARK2_ST	Q6WKZ4	RAB11FIP1	Q7KZI7	MARK2	S6	A7D	7	Missense	proximal	1	no	302.469	302.145	EPSD	COSMIC	271.430	Down-regulation
CAMK_CAMKL_MARK_MARK2_ST	Q6WKZ4	RAB11FIP1	Q7KZI7	MARK2	S6	S6W	6	Missense	central	0	yes	302.469	0.000	EPSD	COSMIC	271.430	Loss
CAMK_CAMKL_MARK_MARK2_ST	Q6WKZ4	RAB11FIP1	Q7KZI7	MARK2	S6	A7T	7	Missense	proximal	1	no	302.469	300.686	EPSD	COSMIC	271.430	Down-regulation
CAMK_CAMKL_MARK_MARK2_ST	Q6WKZ4	RAB11FIP1	Q7KZI7	MARK2	S184	G185S	185	Missense	proximal	1	no	274.526	277.979	EPSD	COSMIC	271.430	Up-regulation
CAMK_CAMKL_MARK_MARK2_ST	Q6WKZ4	RAB11FIP1	Q7KZI7	MARK2	S184	S190T	190	Missense	distal	6	no	274.526	274.128	EPSD	COSMIC	271.430	Down-regulation
CAMK_CAMKL_MARK_MARK2_ST	Q6WKZ4	RAB11FIP1	Q7KZI7	MARK2	S184	K180N	180	Missense	distal	-4	no	274.526	280.569	EPSD	COSMIC	271.430	Up-regulation
CAMK_CAMKL_MARK_MARK2_ST	Q6WKZ4	RAB11FIP1	Q7KZI7	MARK2	S184	S190F	190	Missense	distal	6	no	274.526	277.258	EPSD	COSMIC	271.430	Up-regulation
CAMK_CAMKL_MARK_MARK2_ST	Q6WKZ4	RAB11FIP1	Q7KZI7	MARK2	S184	A189T	189	Missense	distal	5	no	274.526	286.636	EPSD	COSMIC	271.430	Up-regulation
CAMK_CAMKL_MARK_MARK2_ST	Q6WKZ4	RAB11FIP1	Q7KZI7	MARK2	S184	G185W	185	Missense	proximal	1	no	274.526	269.949	EPSD	COSMIC	271.430	Loss
CAMK_CAMKL_MARK_MARK2_ST	Q6WKZ4	RAB11FIP1	Q7KZI7	MARK2	S184	N181K	181	Missense	distal	-3	no	274.526	306.441	EPSD	COSMIC	271.430	Up-regulation
CAMK_CAMKL_MARK_MARK2_ST	Q6WKZ4	RAB11FIP1	Q7KZI7	MARK2	S184	A191T	191	Missense	distal	7	no	274.526	287.818	EPSD	COSMIC	271.430	Up-regulation
CAMK_CAMKL_MARK_MARK2_ST	Q6WKZ4	RAB11FIP1	Q7KZI7	MARK2	S199	S202C	202	Missense	distal	3	no	270.350	298.548	EPSD	COSMIC;GDSC;CCLE	271.430	Gain
CAMK_CAMKL_MARK_MARK2_ST	Q6WKZ4	RAB11FIP1	Q7KZI7	MARK2	T219	L226F	226	Missense	distal	7	no	280.278	272.824	EPSD	COSMIC	271.430	Down-regulation
CAMK_CAMKL_MARK_MARK2_ST	Q6WKZ4	RAB11FIP1	Q7KZI7	MARK2	T219	K218N	218	Missense	proximal	-1	no	280.278	280.855	EPSD	COSMIC;GDSC;CCLE	271.430	Up-regulation
CAMK_CAMKL_MARK_MARK2_ST	Q6WKZ4	RAB11FIP1	Q7KZI7	MARK2	S222	L226F	226	Missense	distal	4	no	289.228	257.717	EPSD	COSMIC	271.430	Loss
CAMK_CAMKL_MARK_MARK2_ST	Q6WKZ4	RAB11FIP1	Q7KZI7	MARK2	S222	K218N	218	Missense	distal	-4	no	289.228	295.271	EPSD	COSMIC;GDSC;CCLE	271.430	Up-regulation
CAMK_CAMKL_MARK_MARK2_ST	Q6WKZ4	RAB11FIP1	Q7KZI7	MARK2	S224	L226F	226	Missense	proximal	2	no	344.013	344.958	EPSD	COSMIC	271.430	Up-regulation
CAMK_CAMKL_MARK_MARK2_ST	Q6WKZ4	RAB11FIP1	Q7KZI7	MARK2	S224	K218N	218	Missense	distal	-6	no	344.013	344.369	EPSD	COSMIC;GDSC;CCLE	271.430	Up-regulation
CAMK_CAMKL_MARK_MARK2_ST	Q6WKZ4	RAB11FIP1	Q7KZI7	MARK2	S234	P239L	239	Missense	distal	5	no	361.908	375.948	PhosphoSitePlus	COSMIC	271.430	Up-regulation
CAMK_CAMKL_MARK_MARK2_ST	Q6WKZ4	RAB11FIP1	Q7KZI7	MARK2	S234	S234C	234	Missense	central	0	yes	361.908	0.000	PhosphoSitePlus	COSMIC	271.430	Loss
CAMK_CAMKL_MARK_MARK2_ST	Q6WKZ4	RAB11FIP1	Q7KZI7	MARK2	S234	S241L	241	Missense	distal	7	no	361.908	371.474	PhosphoSitePlus	COSMIC;GDSC;CCLE	271.430	Up-regulation
CAMK_CAMKL_MARK_MARK2_ST	Q6WKZ4	RAB11FIP1	Q7KZI7	MARK2	S234	M235V	235	Missense	proximal	1	no	361.908	371.733	PhosphoSitePlus	COSMIC	271.430	Up-regulation
CAMK_CAMKL_MARK_MARK2_ST	Q6WKZ4	RAB11FIP1	Q7KZI7	MARK2	S241	P243S	243	Missense	proximal	2	no	258.963	273.687	EPSD	COSMIC	271.430	Gain
CAMK_CAMKL_MARK_MARK2_ST	Q6WKZ4	RAB11FIP1	Q7KZI7	MARK2	S268	D261Y	261	Missense	distal	-7	no	282.540	282.589	EPSD	COSMIC	271.430	Up-regulation
CAMK_CAMKL_MARK_MARK2_ST	Q6WKZ4	RAB11FIP1	Q7KZI7	MARK2	S268	E265K	265	Missense	distal	-3	no	282.540	395.065	EPSD	COSMIC	271.430	Up-regulation
CAMK_CAMKL_MARK_MARK2_ST	Q6WKZ4	RAB11FIP1	Q7KZI7	MARK2	T278	A279V	279	Missense	proximal	1	no	283.416	293.882	EPSD	COSMIC	271.430	Up-regulation
CAMK_CAMKL_MARK_MARK2_ST	Q6WKZ4	RAB11FIP1	Q7KZI7	MARK2	S280	A279V	279	Missense	proximal	-1	no	365.593	357.745	EPSD	COSMIC	271.430	Down-regulation
CAMK_CAMKL_MARK_MARK2_ST	Q6WKZ4	RAB11FIP1	Q7KZI7	MARK2	S307	R314H	314	Missense	distal	7	no	318.660	309.664	EPSD	COSMIC	271.430	Down-regulation
CAMK_CAMKL_MARK_MARK2_ST	Q6WKZ4	RAB11FIP1	Q7KZI7	MARK2	S307	R314C	314	Missense	distal	7	no	318.660	306.345	EPSD	COSMIC	271.430	Down-regulation
CAMK_CAMKL_MARK_MARK2_ST	Q6WKZ4	RAB11FIP1	Q7KZI7	MARK2	S307	L302V	302	Missense	distal	-5	no	318.660	325.564	EPSD	COSMIC	271.430	Up-regulation
CAMK_CAMKL_MARK_MARK2_ST	Q6WKZ4	RAB11FIP1	Q7KZI7	MARK2	S307	R306Q	306	Missense	proximal	-1	no	318.660	300.244	EPSD	COSMIC	271.430	Down-regulation
CAMK_CAMKL_MARK_MARK2_ST	Q6WKZ4	RAB11FIP1	Q7KZI7	MARK2	S315	R314H	314	Missense	proximal	-1	no	297.961	303.083	EPSD	COSMIC	271.430	Up-regulation
CAMK_CAMKL_MARK_MARK2_ST	Q6WKZ4	RAB11FIP1	Q7KZI7	MARK2	S315	G321V	321	Missense	distal	6	no	297.961	288.666	EPSD	COSMIC	271.430	Down-regulation
CAMK_CAMKL_MARK_MARK2_ST	Q6WKZ4	RAB11FIP1	Q7KZI7	MARK2	S315	R314C	314	Missense	proximal	-1	no	297.961	305.312	EPSD	COSMIC	271.430	Up-regulation
CAMK_CAMKL_MARK_MARK2_ST	Q6WKZ4	RAB11FIP1	Q7KZI7	MARK2	S315	G321E	321	Missense	distal	6	no	297.961	290.181	EPSD	COSMIC	271.430	Down-regulation
CAMK_CAMKL_MARK_MARK2_ST	Q6WKZ4	RAB11FIP1	Q7KZI7	MARK2	S315	N322K	322	Missense	distal	7	no	297.961	293.202	EPSD	COSMIC	271.430	Down-regulation
CAMK_CAMKL_MARK_MARK2_ST	Q6WKZ4	RAB11FIP1	Q7KZI7	MARK2	S343	P344Q	344	Missense	proximal	1	no	304.388	302.348	EPSD	COSMIC	271.430	Down-regulation
CAMK_CAMKL_MARK_MARK2_ST	Q6WKZ4	RAB11FIP1	Q7KZI7	MARK2	S343	K347E	347	Missense	distal	4	no	304.388	306.997	EPSD	COSMIC;GDSC;CCLE	271.430	Up-regulation
CAMK_CAMKL_MARK_MARK2_ST	Q6WKZ4	RAB11FIP1	Q7KZI7	MARK2	S356	A363D	363	Missense	distal	7	no	297.849	302.280	EPSD	COSMIC	271.430	Up-regulation
CAMK_CAMKL_MARK_MARK2_ST	Q6WKZ4	RAB11FIP1	Q7KZI7	MARK2	S356	A362G	362	Missense	distal	6	no	297.849	310.302	EPSD	COSMIC	271.430	Up-regulation
CAMK_CAMKL_MARK_MARK2_ST	Q6WKZ4	RAB11FIP1	Q7KZI7	MARK2	S357	A363D	363	Missense	distal	6	no	341.221	347.648	EPSD	COSMIC	271.430	Up-regulation
CAMK_CAMKL_MARK_MARK2_ST	Q6WKZ4	RAB11FIP1	Q7KZI7	MARK2	S357	A362G	362	Missense	distal	5	no	341.221	335.440	EPSD	COSMIC	271.430	Down-regulation
CAMK_CAMKL_MARK_MARK2_ST	Q6WKZ4	RAB11FIP1	Q7KZI7	MARK2	S377	Q380K	380	Missense	distal	3	no	285.422	291.024	EPSD	COSMIC	271.430	Up-regulation
CAMK_CAMKL_MARK_MARK2_ST	Q6WKZ4	RAB11FIP1	Q7KZI7	MARK2	S377	A370V	370	Missense	distal	-7	no	285.422	285.357	EPSD	COSMIC	271.430	Down-regulation
CAMK_CAMKL_MARK_MARK2_ST	Q6WKZ4	RAB11FIP1	Q7KZI7	MARK2	S382	Q380K	380	Missense	proximal	-2	no	291.698	291.681	EPSD	COSMIC	271.430	Down-regulation
CAMK_CAMKL_MARK_MARK2_ST	Q6WKZ4	RAB11FIP1	Q7KZI7	MARK2	S382	S389F	389	Missense	distal	7	no	291.698	293.810	EPSD	COSMIC	271.430	Up-regulation
CAMK_CAMKL_MARK_MARK2_ST	Q6WKZ4	RAB11FIP1	Q7KZI7	MARK2	S435	S434L	434	Missense	proximal	-1	no	329.985	338.550	EPSD	COSMIC	271.430	Up-regulation
CAMK_CAMKL_MARK_MARK2_ST	Q6WKZ4	RAB11FIP1	Q7KZI7	MARK2	S660	P662S	662	Missense	proximal	2	no	305.734	320.457	EPSD	COSMIC	271.430	Up-regulation
CAMK_CAMKL_MARK_MARK2_ST	Q6WKZ4	RAB11FIP1	Q7KZI7	MARK2	S731	S734R	734	Missense	distal	3	no	264.080	274.003	EPSD	COSMIC	271.430	Gain
CAMK_CAMKL_MARK_MARK2_ST	Q6WKZ4	RAB11FIP1	Q7KZI7	MARK2	S733	S734R	734	Missense	proximal	1	no	275.763	277.807	EPSD	COSMIC	271.430	Up-regulation
CAMK_CAMKL_MARK_MARK2_ST	Q6WKZ4	RAB11FIP1	Q7KZI7	MARK2	S958	D954N	954	Missense	distal	-4	no	314.151	316.011	EPSD	COSMIC	271.430	Up-regulation
CAMK_CAMKL_MARK_MARK2_ST	Q6WKZ4	RAB11FIP1	Q7KZI7	MARK2	T1196	T1198S	1198	Missense	proximal	2	no	259.822	290.190	EPSD	COSMIC	271.430	Gain
CMGC_CLK_CLK2_ST	O60829	PAGE4	P49760	CLK2	S7	R4Q	4	Missense	distal	-3	no	0.007	0.006	EPSD;PhosphoSitePlus	COSMIC	0.005	Down-regulation
CMGC_CLK_CLK2_ST	O60829	PAGE4	P49760	CLK2	S9	A3E	3	Missense	distal	-6	no	0.008	0.009	EPSD;PhosphoSitePlus	COSMIC	0.005	Up-regulation
CMGC_CLK_CLK2_ST	O60829	PAGE4	P49760	CLK2	T51	G45E	45	Missense	distal	-6	no	0.007	0.008	EPSD;PhosphoSitePlus	COSMIC	0.005	Up-regulation
CMGC_CLK_CLK2_ST	P18031	PTPN1	P49760	CLK2	S203	G202E	202	Missense	proximal	-1	no	0.004	0.005	EPSD	COSMIC	0.005	Gain
CMGC_CLK_CLK2_ST	P18031	PTPN1	P49760	CLK2	S203	E200K	200	Missense	distal	-3	no	0.004	0.005	EPSD	COSMIC	0.005	Gain
CMGC_CLK_CLK2_ST	P18031	PTPN1	P49760	CLK2	S243	K248T	248	Missense	distal	5	no	0.007	0.006	PhosphoSitePlus;EPSD	COSMIC	0.005	Down-regulation
CMGC_CLK_CLK2_ST	P18031	PTPN1	P49760	CLK2	S270	S270F	270	Missense	central	0	yes	0.006	0.000	EPSD	COSMIC	0.005	Loss
CMGC_CLK_CLK2_ST	P18031	PTPN1	P49760	CLK2	S270	R268H	268	Missense	proximal	-2	no	0.006	0.005	EPSD	COSMIC	0.005	Down-regulation
CMGC_CLK_CLK2_ST	P18031	PTPN1	P49760	CLK2	S363	D367Y	367	Missense	distal	4	no	0.005	0.004	EPSD	COSMIC	0.005	Loss
AGC_SGK_SGK1_ST	O00213	APBB1	O00141	SGK1	T92	L95Q	95	Missense	distal	3	no	9.998	10.142	EPSD	COSMIC	9.140	Up-regulation
AGC_SGK_SGK1_ST	O00213	APBB1	O00141	SGK1	S289	E296V	296	Missense	distal	7	no	10.163	10.349	EPSD	COSMIC	9.140	Up-regulation
AGC_SGK_SGK1_ST	O00213	APBB1	O00141	SGK1	S289	P283L	283	Missense	distal	-6	no	10.163	10.245	EPSD	COSMIC	9.140	Up-regulation
AGC_SGK_SGK1_ST	O00213	APBB1	O00141	SGK1	S289	P288T	288	Missense	proximal	-1	no	10.163	10.320	EPSD	COSMIC	9.140	Up-regulation
AGC_SGK_SGK1_ST	O00213	APBB1	O00141	SGK1	S289	S293I	293	Missense	distal	4	no	10.163	9.919	EPSD	COSMIC	9.140	Down-regulation
AGC_SGK_SGK1_ST	O00213	APBB1	O00141	SGK1	S289	R285P	285	Missense	distal	-4	no	10.163	9.457	EPSD	COSMIC	9.140	Down-regulation
AGC_SGK_SGK1_ST	O00213	APBB1	O00141	SGK1	S610	G615S	615	Missense	distal	5	no	18.399	18.452	PhosphoSitePlus	COSMIC	9.140	Up-regulation
AGC_SGK_SGK1_ST	O00213	APBB1	O00141	SGK1	S610	A613T	613	Missense	distal	3	no	18.399	18.277	PhosphoSitePlus	COSMIC;CCLE	9.140	Down-regulation
AGC_SGK_SGK1_ST	O00213	APBB1	O00141	SGK1	S610	V614M	614	Missense	distal	4	no	18.399	18.523	PhosphoSitePlus	COSMIC	9.140	Up-regulation
AGC_SGK_SGK1_ST	O00213	APBB1	O00141	SGK1	S610	V614A	614	Missense	distal	4	no	18.399	18.708	PhosphoSitePlus	COSMIC	9.140	Up-regulation
AGC_SGK_SGK1_ST	O00213	APBB1	O00141	SGK1	S695	R690H	690	Missense	distal	-5	no	9.621	2.288	EPSD	COSMIC	9.140	Loss
AGC_SGK_SGK1_ST	O00213	APBB1	O00141	SGK1	T709	K703T	703	Missense	distal	-6	no	9.547	9.357	EPSD	COSMIC	9.140	Down-regulation
AGC_SGK_SGK1_ST	O00213	APBB1	O00141	SGK1	T709	L705M	705	Missense	distal	-4	no	9.547	9.352	EPSD	COSMIC	9.140	Down-regulation
AGC_SGK_SGK1_ST	Q92597	NDRG1	O00141	SGK1	T328	R325Q	325	Missense	distal	-3	no	15.782	5.119	EPSD;PhosphoSitePlus	COSMIC	9.140	Loss
AGC_SGK_SGK1_ST	Q92597	NDRG1	O00141	SGK1	S330	R325Q	325	Missense	distal	-5	no	21.313	13.162	EPSD;PhosphoSitePlus	COSMIC	9.140	Down-regulation
AGC_SGK_SGK1_ST	Q92597	NDRG1	O00141	SGK1	S332	R325Q	325	Missense	distal	-7	no	15.370	15.899	EPSD	COSMIC	9.140	Up-regulation
AGC_SGK_SGK1_ST	Q92597	NDRG1	O00141	SGK1	T346	S352I	352	Missense	distal	6	no	19.397	19.143	PhosphoSitePlus;EPSD	COSMIC	9.140	Down-regulation
AGC_SGK_SGK1_ST	Q92597	NDRG1	O00141	SGK1	S354	R361S	361	Missense	distal	7	no	16.892	16.841	EPSD	COSMIC	9.140	Down-regulation
AGC_SGK_SGK1_ST	Q92597	NDRG1	O00141	SGK1	S354	R361H	361	Missense	distal	7	no	16.892	16.976	EPSD	COSMIC;CCLE	9.140	Up-regulation
AGC_SGK_SGK1_ST	Q92597	NDRG1	O00141	SGK1	S354	S352I	352	Missense	proximal	-2	no	16.892	16.439	EPSD	COSMIC	9.140	Down-regulation
AGC_SGK_SGK1_ST	Q92597	NDRG1	O00141	SGK1	S354	H355Y	355	Missense	proximal	1	no	16.892	16.988	EPSD	COSMIC	9.140	Up-regulation
AGC_SGK_SGK1_ST	Q92597	NDRG1	O00141	SGK1	T356	R361S	361	Missense	distal	5	no	17.543	17.556	EPSD;PhosphoSitePlus	COSMIC	9.140	Up-regulation
AGC_SGK_SGK1_ST	Q92597	NDRG1	O00141	SGK1	T356	R361H	361	Missense	distal	5	no	17.543	17.524	EPSD;PhosphoSitePlus	COSMIC;CCLE	9.140	Down-regulation
AGC_SGK_SGK1_ST	Q92597	NDRG1	O00141	SGK1	T356	S352I	352	Missense	distal	-4	no	17.543	16.209	EPSD;PhosphoSitePlus	COSMIC	9.140	Down-regulation
AGC_SGK_SGK1_ST	Q92597	NDRG1	O00141	SGK1	T356	H355Y	355	Missense	proximal	-1	no	17.543	17.504	EPSD;PhosphoSitePlus	COSMIC	9.140	Down-regulation
AGC_SGK_SGK1_ST	Q92597	NDRG1	O00141	SGK1	S364	R361S	361	Missense	distal	-3	no	15.470	8.564	EPSD	COSMIC	9.140	Loss
AGC_SGK_SGK1_ST	Q92597	NDRG1	O00141	SGK1	S364	R361H	361	Missense	distal	-3	no	15.470	5.852	EPSD	COSMIC;CCLE	9.140	Loss
AGC_SGK_SGK1_ST	Q92597	NDRG1	O00141	SGK1	S364	H365Y	365	Missense	proximal	1	no	15.470	15.566	EPSD	COSMIC	9.140	Up-regulation
AGC_SGK_SGK1_ST	Q92597	NDRG1	O00141	SGK1	T366	R361S	361	Missense	distal	-5	no	19.819	14.574	EPSD;PhosphoSitePlus	COSMIC	9.140	Down-regulation
AGC_SGK_SGK1_ST	Q92597	NDRG1	O00141	SGK1	T366	R361H	361	Missense	distal	-5	no	19.819	12.486	EPSD;PhosphoSitePlus	COSMIC;CCLE	9.140	Down-regulation
AGC_SGK_SGK1_ST	Q92597	NDRG1	O00141	SGK1	T366	H365Y	365	Missense	proximal	-1	no	19.819	19.780	EPSD;PhosphoSitePlus	COSMIC	9.140	Down-regulation
AGC_SGK_SGK1_ST	Q96PU5	NEDD4L	O00141	SGK1	S256	R253M	253	Missense	distal	-3	no	12.531	2.990	EPSD	COSMIC	9.140	Loss
AGC_SGK_SGK1_ST	Q96PU5	NEDD4L	O00141	SGK1	S256	H254Y	254	Missense	proximal	-2	no	12.531	12.719	EPSD	COSMIC	9.140	Up-regulation
AGC_SGK_SGK1_ST	Q96PU5	NEDD4L	O00141	SGK1	S256	S256R	256	Missense	central	0	yes	12.531	0.000	EPSD	COSMIC	9.140	Loss
AGC_SGK_SGK1_ST	Q96PU5	NEDD4L	O00141	SGK1	S256	R250C	250	Missense	distal	-6	no	12.531	12.466	EPSD	COSMIC;GDSC;CCLE	9.140	Down-regulation
AGC_SGK_SGK1_ST	Q96PU5	NEDD4L	O00141	SGK1	S256	E257K	257	Missense	proximal	1	no	12.531	12.363	EPSD	COSMIC	9.140	Down-regulation
AGC_SGK_SGK1_ST	Q96PU5	NEDD4L	O00141	SGK1	T318	R314K	314	Missense	distal	-4	no	12.455	12.636	EPSD	COSMIC	9.140	Up-regulation
AGC_SGK_SGK1_ST	Q96PU5	NEDD4L	O00141	SGK1	T318	L315I	315	Missense	distal	-3	no	12.455	9.261	EPSD	COSMIC	9.140	Down-regulation
AGC_SGK_SGK1_ST	Q96PU5	NEDD4L	O00141	SGK1	S335	S342I	342	Missense	distal	7	no	9.132	9.551	EPSD	COSMIC	9.140	Gain
AGC_SGK_SGK1_ST	Q96PU5	NEDD4L	O00141	SGK1	S335	S342N	342	Missense	distal	7	no	9.132	9.242	EPSD	COSMIC	9.140	Gain
AGC_SGK_SGK1_ST	Q96PU5	NEDD4L	O00141	SGK1	S340	D345N	345	Missense	distal	5	no	16.090	16.114	EPSD	COSMIC	9.140	Up-regulation
AGC_SGK_SGK1_ST	Q96PU5	NEDD4L	O00141	SGK1	S340	S342I	342	Missense	proximal	2	no	16.090	16.516	EPSD	COSMIC	9.140	Up-regulation
AGC_SGK_SGK1_ST	Q96PU5	NEDD4L	O00141	SGK1	S340	S342N	342	Missense	proximal	2	no	16.090	16.053	EPSD	COSMIC	9.140	Down-regulation
AGC_SGK_SGK1_ST	Q96PU5	NEDD4L	O00141	SGK1	S342	D345N	345	Missense	distal	3	no	16.913	17.003	PhosphoSitePlus;EPSD	COSMIC	9.140	Up-regulation
AGC_SGK_SGK1_ST	Q96PU5	NEDD4L	O00141	SGK1	S342	S342I	342	Missense	central	0	yes	16.913	0.000	PhosphoSitePlus;EPSD	COSMIC	9.140	Loss
AGC_SGK_SGK1_ST	Q96PU5	NEDD4L	O00141	SGK1	S342	S342N	342	Missense	central	0	yes	16.913	0.000	PhosphoSitePlus;EPSD	COSMIC	9.140	Loss
AGC_SGK_SGK1_ST	Q96PU5	NEDD4L	O00141	SGK1	S365	R364L	364	Missense	proximal	-1	no	10.437	10.323	EPSD	COSMIC	9.140	Down-regulation
AGC_SGK_SGK1_ST	Q96PU5	NEDD4L	O00141	SGK1	S365	R364W	364	Missense	proximal	-1	no	10.437	10.195	EPSD	COSMIC	9.140	Down-regulation
AGC_SGK_SGK1_ST	Q96PU5	NEDD4L	O00141	SGK1	S365	T369I	369	Missense	distal	4	no	10.437	10.250	EPSD	COSMIC	9.140	Down-regulation
AGC_SGK_SGK1_ST	Q96PU5	NEDD4L	O00141	SGK1	S365	R364G	364	Missense	proximal	-1	no	10.437	10.212	EPSD	COSMIC	9.140	Down-regulation
AGC_SGK_SGK1_ST	Q96PU5	NEDD4L	O00141	SGK1	S365	S365L	365	Missense	central	0	yes	10.437	0.000	EPSD	COSMIC	9.140	Loss
AGC_SGK_SGK1_ST	Q96PU5	NEDD4L	O00141	SGK1	S365	T367M	367	Missense	proximal	2	no	10.437	10.557	EPSD	COSMIC	9.140	Up-regulation
AGC_SGK_SGK1_ST	Q96PU5	NEDD4L	O00141	SGK1	T367	R364L	364	Missense	distal	-3	no	14.642	9.294	EPSD;PhosphoSitePlus	COSMIC	9.140	Down-regulation
AGC_SGK_SGK1_ST	Q96PU5	NEDD4L	O00141	SGK1	T367	R364W	364	Missense	distal	-3	no	14.642	4.947	EPSD;PhosphoSitePlus	COSMIC	9.140	Loss
AGC_SGK_SGK1_ST	Q96PU5	NEDD4L	O00141	SGK1	T367	T369I	369	Missense	proximal	2	no	14.642	14.876	EPSD;PhosphoSitePlus	COSMIC	9.140	Up-regulation
AGC_SGK_SGK1_ST	Q96PU5	NEDD4L	O00141	SGK1	T367	R364G	364	Missense	distal	-3	no	14.642	8.086	EPSD;PhosphoSitePlus	COSMIC	9.140	Loss
AGC_SGK_SGK1_ST	Q96PU5	NEDD4L	O00141	SGK1	T367	S365L	365	Missense	proximal	-2	no	14.642	14.530	EPSD;PhosphoSitePlus	COSMIC	9.140	Down-regulation
AGC_SGK_SGK1_ST	Q96PU5	NEDD4L	O00141	SGK1	T367	P374A	374	Missense	distal	7	no	14.642	14.342	EPSD;PhosphoSitePlus	COSMIC	9.140	Down-regulation
AGC_SGK_SGK1_ST	Q96PU5	NEDD4L	O00141	SGK1	T367	T367M	367	Missense	central	0	yes	14.642	0.000	EPSD;PhosphoSitePlus	COSMIC	9.140	Loss
AGC_SGK_SGK1_ST	Q96PU5	NEDD4L	O00141	SGK1	S446	S448G	448	Missense	proximal	2	no	10.603	10.929	EPSD	COSMIC	9.140	Up-regulation
AGC_SGK_SGK1_ST	Q96PU5	NEDD4L	O00141	SGK1	S446	R445H	445	Missense	proximal	-1	no	10.603	10.491	EPSD	COSMIC	9.140	Down-regulation
AGC_SGK_SGK1_ST	Q96PU5	NEDD4L	O00141	SGK1	S446	T453I	453	Missense	distal	7	no	10.603	10.928	EPSD	COSMIC	9.140	Up-regulation
AGC_SGK_SGK1_ST	Q96PU5	NEDD4L	O00141	SGK1	S448	S448G	448	Missense	central	0	yes	16.907	0.000	EPSD;PhosphoSitePlus	COSMIC	9.140	Loss
AGC_SGK_SGK1_ST	Q96PU5	NEDD4L	O00141	SGK1	S448	R445H	445	Missense	distal	-3	no	16.907	7.288	EPSD;PhosphoSitePlus	COSMIC	9.140	Loss
AGC_SGK_SGK1_ST	Q96PU5	NEDD4L	O00141	SGK1	S448	T453I	453	Missense	distal	5	no	16.907	16.844	EPSD;PhosphoSitePlus	COSMIC	9.140	Down-regulation
AGC_SGK_SGK1_ST	Q96PU5	NEDD4L	O00141	SGK1	T473	D472V	472	Missense	proximal	-1	no	9.493	9.426	EPSD	COSMIC	9.140	Down-regulation
AGC_SGK_SGK1_ST	Q96PU5	NEDD4L	O00141	SGK1	T473	V470F	470	Missense	distal	-3	no	9.493	11.089	EPSD	COSMIC	9.140	Up-regulation
AGC_SGK_SGK1_ST	Q96PU5	NEDD4L	O00141	SGK1	T473	Q478H	478	Missense	distal	5	no	9.493	9.503	EPSD	COSMIC	9.140	Up-regulation
AGC_SGK_SGK1_ST	Q96PU5	NEDD4L	O00141	SGK1	T473	R468L	468	Missense	distal	-5	no	9.493	5.266	EPSD	COSMIC	9.140	Loss
AGC_SGK_SGK1_ST	Q96PU5	NEDD4L	O00141	SGK1	T473	T473I	473	Missense	central	0	yes	9.493	0.000	EPSD	COSMIC	9.140	Loss
AGC_SGK_SGK1_ST	Q96PU5	NEDD4L	O00141	SGK1	T473	R468G	468	Missense	distal	-5	no	9.493	4.133	EPSD	COSMIC	9.140	Loss
AGC_SGK_SGK1_ST	Q96PU5	NEDD4L	O00141	SGK1	T473	P480T	480	Missense	distal	7	no	9.493	9.194	EPSD	COSMIC	9.140	Down-regulation
AGC_SGK_SGK1_ST	Q96PU5	NEDD4L	O00141	SGK1	T540	V534M	534	Missense	distal	-6	no	9.972	10.209	EPSD	COSMIC	9.140	Up-regulation
AGC_SGK_SGK1_ST	Q96PU5	NEDD4L	O00141	SGK1	S637	P641A	641	Missense	distal	4	no	11.349	11.570	EPSD	COSMIC	9.140	Up-regulation
AGC_SGK_SGK1_ST	Q96PU5	NEDD4L	O00141	SGK1	S637	M636I	636	Missense	proximal	-1	no	11.349	11.320	EPSD	COSMIC	9.140	Down-regulation
AGC_SGK_SGK1_ST	Q96PU5	NEDD4L	O00141	SGK1	S637	V638M	638	Missense	proximal	1	no	11.349	11.290	EPSD	COSMIC	9.140	Down-regulation
AGC_SGK_SGK1_ST	Q96PU5	NEDD4L	O00141	SGK1	S637	E630Q	630	Missense	distal	-7	no	11.349	11.145	EPSD	COSMIC	9.140	Down-regulation
AGC_SGK_SGK1_ST	Q96PU5	NEDD4L	O00141	SGK1	S637	Y632N	632	Missense	distal	-5	no	11.349	9.102	EPSD	COSMIC	9.140	Loss
AGC_SGK_SGK1_ST	P49815	TSC2	O00141	SGK1	S311	G305E	305	Missense	distal	-6	no	13.397	13.414	EPSD	COSMIC	9.140	Up-regulation
AGC_SGK_SGK1_ST	P49815	TSC2	O00141	SGK1	S311	A306T	306	Missense	distal	-5	no	13.397	13.282	EPSD	COSMIC	9.140	Down-regulation
AGC_SGK_SGK1_ST	P49815	TSC2	O00141	SGK1	S311	Y310C	310	Missense	proximal	-1	no	13.397	13.429	EPSD	COSMIC	9.140	Up-regulation
AGC_SGK_SGK1_ST	P49815	TSC2	O00141	SGK1	S311	P316L	316	Missense	distal	5	no	13.397	13.420	EPSD	COSMIC	9.140	Up-regulation
AGC_SGK_SGK1_ST	P49815	TSC2	O00141	SGK1	S311	S311Y	311	Missense	central	0	yes	13.397	0.000	EPSD	COSMIC	9.140	Loss
AGC_SGK_SGK1_ST	P49815	TSC2	O00141	SGK1	S311	G305V	305	Missense	distal	-6	no	13.397	13.163	EPSD	COSMIC	9.140	Down-regulation
AGC_SGK_SGK1_ST	P49815	TSC2	O00141	SGK1	S311	A306S	306	Missense	distal	-5	no	13.397	12.209	EPSD	COSMIC	9.140	Down-regulation
AGC_SGK_SGK1_ST	P49815	TSC2	O00141	SGK1	S540	S540F	540	Missense	central	0	yes	9.702	0.000	EPSD	COSMIC	9.140	Loss
AGC_SGK_SGK1_ST	P49815	TSC2	O00141	SGK1	S540	P542L	542	Missense	proximal	2	no	9.702	9.809	EPSD	COSMIC	9.140	Up-regulation
AGC_SGK_SGK1_ST	P49815	TSC2	O00141	SGK1	S540	S538P	538	Missense	proximal	-2	no	9.702	9.215	EPSD	COSMIC	9.140	Down-regulation
AGC_SGK_SGK1_ST	P49815	TSC2	O00141	SGK1	S540	L539F	539	Missense	proximal	-1	no	9.702	9.483	EPSD	COSMIC	9.140	Down-regulation
AGC_SGK_SGK1_ST	P49815	TSC2	O00141	SGK1	S540	P543Q	543	Missense	distal	3	no	9.702	9.856	EPSD	COSMIC	9.140	Up-regulation
AGC_SGK_SGK1_ST	P49815	TSC2	O00141	SGK1	S939	E942K	942	Missense	distal	3	no	14.517	14.836	EPSD;PhosphoSitePlus	COSMIC	9.140	Up-regulation
AGC_SGK_SGK1_ST	P49815	TSC2	O00141	SGK1	S939	R936Q	936	Missense	distal	-3	no	14.517	3.854	EPSD;PhosphoSitePlus	COSMIC	9.140	Loss
AGC_SGK_SGK1_ST	P49815	TSC2	O00141	SGK1	S939	K945E	945	Missense	distal	6	no	14.517	14.330	EPSD;PhosphoSitePlus	COSMIC	9.140	Down-regulation
AGC_SGK_SGK1_ST	P49815	TSC2	O00141	SGK1	S939	A935S	935	Missense	distal	-4	no	14.517	14.631	EPSD;PhosphoSitePlus	COSMIC	9.140	Up-regulation
AGC_SGK_SGK1_ST	P49815	TSC2	O00141	SGK1	S939	S932N	932	Missense	distal	-7	no	14.517	14.594	EPSD;PhosphoSitePlus	COSMIC	9.140	Up-regulation
AGC_SGK_SGK1_ST	P49815	TSC2	O00141	SGK1	S939	S946I	946	Missense	distal	7	no	14.517	14.936	EPSD;PhosphoSitePlus	COSMIC	9.140	Up-regulation
AGC_SGK_SGK1_ST	P49815	TSC2	O00141	SGK1	S939	T938I	938	Missense	proximal	-1	no	14.517	14.376	EPSD;PhosphoSitePlus	COSMIC	9.140	Down-regulation
AGC_SGK_SGK1_ST	P49815	TSC2	O00141	SGK1	S979	S979R	979	Missense	central	0	yes	11.403	0.000	EPSD	COSMIC	9.140	Loss
AGC_SGK_SGK1_ST	P49815	TSC2	O00141	SGK1	S979	E984V	984	Missense	distal	5	no	11.403	11.355	EPSD	COSMIC	9.140	Down-regulation
AGC_SGK_SGK1_ST	P49815	TSC2	O00141	SGK1	S979	R976W	976	Missense	distal	-3	no	11.403	1.708	EPSD	COSMIC	9.140	Loss
AGC_SGK_SGK1_ST	P49815	TSC2	O00141	SGK1	S979	S981R	981	Missense	proximal	2	no	11.403	11.702	EPSD	COSMIC	9.140	Up-regulation
AGC_SGK_SGK1_ST	P49815	TSC2	O00141	SGK1	S979	V982I	982	Missense	distal	3	no	11.403	11.539	EPSD	COSMIC	9.140	Up-regulation
AGC_SGK_SGK1_ST	P49815	TSC2	O00141	SGK1	S981	R988Q	988	Missense	distal	7	no	15.889	16.089	EPSD;PhosphoSitePlus	COSMIC	9.140	Up-regulation
AGC_SGK_SGK1_ST	P49815	TSC2	O00141	SGK1	S981	S979R	979	Missense	proximal	-2	no	15.889	15.987	EPSD;PhosphoSitePlus	COSMIC	9.140	Up-regulation
AGC_SGK_SGK1_ST	P49815	TSC2	O00141	SGK1	S981	E984V	984	Missense	distal	3	no	15.889	15.572	EPSD;PhosphoSitePlus	COSMIC	9.140	Down-regulation
AGC_SGK_SGK1_ST	P49815	TSC2	O00141	SGK1	S981	R976W	976	Missense	distal	-5	no	15.889	8.231	EPSD;PhosphoSitePlus	COSMIC	9.140	Loss
AGC_SGK_SGK1_ST	P49815	TSC2	O00141	SGK1	S981	S981R	981	Missense	central	0	yes	15.889	0.000	EPSD;PhosphoSitePlus	COSMIC	9.140	Loss
AGC_SGK_SGK1_ST	P49815	TSC2	O00141	SGK1	S981	V982I	982	Missense	proximal	1	no	15.889	15.867	EPSD;PhosphoSitePlus	COSMIC	9.140	Down-regulation
AGC_SGK_SGK1_ST	P49815	TSC2	O00141	SGK1	S981	V987A	987	Missense	distal	6	no	15.889	16.182	EPSD;PhosphoSitePlus	COSMIC	9.140	Up-regulation
AGC_SGK_SGK1_ST	P49815	TSC2	O00141	SGK1	S983	R988Q	988	Missense	distal	5	no	11.799	11.770	EPSD	COSMIC	9.140	Down-regulation
AGC_SGK_SGK1_ST	P49815	TSC2	O00141	SGK1	S983	S979R	979	Missense	distal	-4	no	11.799	11.494	EPSD	COSMIC	9.140	Down-regulation
AGC_SGK_SGK1_ST	P49815	TSC2	O00141	SGK1	S983	E984V	984	Missense	proximal	1	no	11.799	11.894	EPSD	COSMIC	9.140	Up-regulation
AGC_SGK_SGK1_ST	P49815	TSC2	O00141	SGK1	S983	R976W	976	Missense	distal	-7	no	11.799	12.913	EPSD	COSMIC	9.140	Up-regulation
AGC_SGK_SGK1_ST	P49815	TSC2	O00141	SGK1	S983	S981R	981	Missense	proximal	-2	no	11.799	11.897	EPSD	COSMIC	9.140	Up-regulation
AGC_SGK_SGK1_ST	P49815	TSC2	O00141	SGK1	S983	V982I	982	Missense	proximal	-1	no	11.799	11.843	EPSD	COSMIC	9.140	Up-regulation
AGC_SGK_SGK1_ST	P49815	TSC2	O00141	SGK1	S983	V987A	987	Missense	distal	4	no	11.799	12.108	EPSD	COSMIC	9.140	Up-regulation
AGC_SGK_SGK1_ST	P49815	TSC2	O00141	SGK1	T993	R988Q	988	Missense	distal	-5	no	17.102	8.951	EPSD	COSMIC	9.140	Loss
AGC_SGK_SGK1_ST	P49815	TSC2	O00141	SGK1	T993	T993M	993	Missense	central	0	yes	17.102	0.000	EPSD	COSMIC	9.140	Loss
AGC_SGK_SGK1_ST	P49815	TSC2	O00141	SGK1	T993	S999T	999	Missense	distal	6	no	17.102	17.038	EPSD	COSMIC	9.140	Down-regulation
AGC_SGK_SGK1_ST	P49815	TSC2	O00141	SGK1	T993	S999L	999	Missense	distal	6	no	17.102	16.988	EPSD	COSMIC	9.140	Down-regulation
AGC_SGK_SGK1_ST	P49815	TSC2	O00141	SGK1	T993	V987A	987	Missense	distal	-6	no	17.102	17.495	EPSD	COSMIC	9.140	Up-regulation
AGC_SGK_SGK1_ST	P49815	TSC2	O00141	SGK1	T993	S999P	999	Missense	distal	6	no	17.102	16.901	EPSD	COSMIC	9.140	Down-regulation
AGC_SGK_SGK1_ST	P49815	TSC2	O00141	SGK1	S1002	S999T	999	Missense	distal	-3	no	7.952	9.510	EPSD	COSMIC	9.140	Gain
AGC_SGK_SGK1_ST	P49815	TSC2	O00141	SGK1	S1002	S999L	999	Missense	distal	-3	no	7.952	9.509	EPSD	COSMIC	9.140	Gain
AGC_SGK_SGK1_ST	P49815	TSC2	O00141	SGK1	S1007	S1002L	1002	Missense	distal	-5	no	8.529	9.546	EPSD	COSMIC	9.140	Gain
AGC_SGK_SGK1_ST	P49815	TSC2	O00141	SGK1	S1014	V1008M	1008	Missense	distal	-6	no	9.087	9.324	EPSD	COSMIC;CCLE	9.140	Gain
AGC_SGK_SGK1_ST	P49815	TSC2	O00141	SGK1	S1079	G1074R	1074	Missense	distal	-5	no	5.119	10.479	EPSD	COSMIC	9.140	Gain
AGC_SGK_SGK1_ST	P49815	TSC2	O00141	SGK1	S1090	E1087K	1087	Missense	distal	-3	no	7.092	11.436	EPSD	COSMIC	9.140	Gain
AGC_SGK_SGK1_ST	P49815	TSC2	O00141	SGK1	S1130	V1128I	1128	Missense	proximal	-2	no	18.186	18.521	EPSD;PhosphoSitePlus	COSMIC	9.140	Up-regulation
AGC_SGK_SGK1_ST	P49815	TSC2	O00141	SGK1	S1130	M1131L	1131	Missense	proximal	1	no	18.186	18.178	EPSD;PhosphoSitePlus	COSMIC	9.140	Down-regulation
AGC_SGK_SGK1_ST	P49815	TSC2	O00141	SGK1	S1130	A1124V	1124	Missense	distal	-6	no	18.186	17.793	EPSD;PhosphoSitePlus	COSMIC;CCLE	9.140	Down-regulation
AGC_SGK_SGK1_ST	P49815	TSC2	O00141	SGK1	S1130	R1125Q	1125	Missense	distal	-5	no	18.186	10.035	EPSD;PhosphoSitePlus	COSMIC	9.140	Down-regulation
AGC_SGK_SGK1_ST	P49815	TSC2	O00141	SGK1	S1130	R1127W	1127	Missense	distal	-3	no	18.186	8.491	EPSD;PhosphoSitePlus	COSMIC	9.140	Loss
AGC_SGK_SGK1_ST	P49815	TSC2	O00141	SGK1	S1130	S1132L	1132	Missense	proximal	2	no	18.186	18.474	EPSD;PhosphoSitePlus	COSMIC	9.140	Up-regulation
AGC_SGK_SGK1_ST	P49815	TSC2	O00141	SGK1	S1130	R1129C	1129	Missense	proximal	-1	no	18.186	18.066	EPSD;PhosphoSitePlus	COSMIC	9.140	Down-regulation
AGC_SGK_SGK1_ST	P49815	TSC2	O00141	SGK1	S1130	S1130C	1130	Missense	central	0	yes	18.186	0.000	EPSD;PhosphoSitePlus	COSMIC	9.140	Loss
AGC_SGK_SGK1_ST	P49815	TSC2	O00141	SGK1	S1130	H1135R	1135	Missense	distal	5	no	18.186	18.205	EPSD;PhosphoSitePlus	COSMIC	9.140	Up-regulation
AGC_SGK_SGK1_ST	P49815	TSC2	O00141	SGK1	S1130	G1134S	1134	Missense	distal	4	no	18.186	18.418	EPSD;PhosphoSitePlus	COSMIC	9.140	Up-regulation
AGC_SGK_SGK1_ST	P49815	TSC2	O00141	SGK1	S1132	V1128I	1128	Missense	distal	-4	no	18.303	18.618	EPSD;PhosphoSitePlus	COSMIC	9.140	Up-regulation
AGC_SGK_SGK1_ST	P49815	TSC2	O00141	SGK1	S1132	M1131L	1131	Missense	proximal	-1	no	18.303	18.360	EPSD;PhosphoSitePlus	COSMIC	9.140	Up-regulation
AGC_SGK_SGK1_ST	P49815	TSC2	O00141	SGK1	S1132	R1125Q	1125	Missense	distal	-7	no	18.303	18.832	EPSD;PhosphoSitePlus	COSMIC	9.140	Up-regulation
AGC_SGK_SGK1_ST	P49815	TSC2	O00141	SGK1	S1132	R1127W	1127	Missense	distal	-5	no	18.303	10.645	EPSD;PhosphoSitePlus	COSMIC	9.140	Down-regulation
AGC_SGK_SGK1_ST	P49815	TSC2	O00141	SGK1	S1132	S1132L	1132	Missense	central	0	yes	18.303	0.000	EPSD;PhosphoSitePlus	COSMIC	9.140	Loss
AGC_SGK_SGK1_ST	P49815	TSC2	O00141	SGK1	S1132	R1129C	1129	Missense	distal	-3	no	18.303	10.241	EPSD;PhosphoSitePlus	COSMIC	9.140	Down-regulation
AGC_SGK_SGK1_ST	P49815	TSC2	O00141	SGK1	S1132	S1130C	1130	Missense	proximal	-2	no	18.303	18.176	EPSD;PhosphoSitePlus	COSMIC	9.140	Down-regulation
AGC_SGK_SGK1_ST	P49815	TSC2	O00141	SGK1	S1132	H1135R	1135	Missense	distal	3	no	18.303	18.368	EPSD;PhosphoSitePlus	COSMIC	9.140	Up-regulation
AGC_SGK_SGK1_ST	P49815	TSC2	O00141	SGK1	S1132	G1134S	1134	Missense	proximal	2	no	18.303	17.977	EPSD;PhosphoSitePlus	COSMIC	9.140	Down-regulation
AGC_SGK_SGK1_ST	P49815	TSC2	O00141	SGK1	T1271	P1265S	1265	Missense	distal	-6	no	15.277	15.545	EPSD	COSMIC	9.140	Up-regulation
AGC_SGK_SGK1_ST	P49815	TSC2	O00141	SGK1	T1271	L1278M	1278	Missense	distal	7	no	15.277	15.231	EPSD	COSMIC	9.140	Down-regulation
AGC_SGK_SGK1_ST	P49815	TSC2	O00141	SGK1	T1271	S1274P	1274	Missense	distal	3	no	15.277	14.880	EPSD	COSMIC	9.140	Down-regulation
AGC_SGK_SGK1_ST	P49815	TSC2	O00141	SGK1	T1271	A1273V	1273	Missense	proximal	2	no	15.277	15.619	EPSD	COSMIC	9.140	Up-regulation
AGC_SGK_SGK1_ST	P49815	TSC2	O00141	SGK1	T1271	R1268G	1268	Missense	distal	-3	no	15.277	8.720	EPSD	COSMIC	9.140	Loss
AGC_SGK_SGK1_ST	P49815	TSC2	O00141	SGK1	T1271	S1276L	1276	Missense	distal	5	no	15.277	15.234	EPSD	COSMIC	9.140	Down-regulation
AGC_SGK_SGK1_ST	P49815	TSC2	O00141	SGK1	T1271	S1274N	1274	Missense	distal	3	no	15.277	15.148	EPSD	COSMIC	9.140	Down-regulation
AGC_SGK_SGK1_ST	P49815	TSC2	O00141	SGK1	T1271	S1269L	1269	Missense	proximal	-2	no	15.277	15.165	EPSD	COSMIC	9.140	Down-regulation
AGC_SGK_SGK1_ST	P49815	TSC2	O00141	SGK1	S1337	S1334R	1334	Missense	distal	-3	no	5.595	12.501	EPSD	COSMIC	9.140	Gain
AGC_SGK_SGK1_ST	P49815	TSC2	O00141	SGK1	S1338	S1334C	1334	Missense	distal	-4	no	13.956	13.464	EPSD	COSMIC	9.140	Down-regulation
AGC_SGK_SGK1_ST	P49815	TSC2	O00141	SGK1	S1338	S1341F	1341	Missense	distal	3	no	13.956	13.149	EPSD	COSMIC	9.140	Down-regulation
AGC_SGK_SGK1_ST	P49815	TSC2	O00141	SGK1	S1338	A1332V	1332	Missense	distal	-6	no	13.956	13.563	EPSD	COSMIC	9.140	Down-regulation
AGC_SGK_SGK1_ST	P49815	TSC2	O00141	SGK1	S1338	E1344D	1344	Missense	distal	6	no	13.956	13.922	EPSD	COSMIC	9.140	Down-regulation
AGC_SGK_SGK1_ST	P49815	TSC2	O00141	SGK1	S1338	S1334R	1334	Missense	distal	-4	no	13.956	13.650	EPSD	COSMIC	9.140	Down-regulation
AGC_SGK_SGK1_ST	P49815	TSC2	O00141	SGK1	S1338	R1335Q	1335	Missense	distal	-3	no	13.956	3.293	EPSD	COSMIC	9.140	Loss
AGC_SGK_SGK1_ST	P49815	TSC2	O00141	SGK1	S1340	S1334C	1334	Missense	distal	-6	no	12.632	12.525	EPSD	COSMIC	9.140	Down-regulation
AGC_SGK_SGK1_ST	P49815	TSC2	O00141	SGK1	S1340	S1341F	1341	Missense	proximal	1	no	12.632	12.868	EPSD	COSMIC	9.140	Up-regulation
AGC_SGK_SGK1_ST	P49815	TSC2	O00141	SGK1	S1340	E1344D	1344	Missense	distal	4	no	12.632	12.652	EPSD	COSMIC	9.140	Up-regulation
AGC_SGK_SGK1_ST	P49815	TSC2	O00141	SGK1	S1340	S1334R	1334	Missense	distal	-6	no	12.632	12.590	EPSD	COSMIC	9.140	Down-regulation
AGC_SGK_SGK1_ST	P49815	TSC2	O00141	SGK1	S1340	S1346C	1346	Missense	distal	6	no	12.632	12.562	EPSD	COSMIC	9.140	Down-regulation
AGC_SGK_SGK1_ST	P49815	TSC2	O00141	SGK1	S1340	R1335Q	1335	Missense	distal	-5	no	12.632	4.481	EPSD	COSMIC	9.140	Loss
AGC_SGK_SGK1_ST	P49815	TSC2	O00141	SGK1	S1364	S1365L	1365	Missense	proximal	1	no	10.900	10.958	EPSD	COSMIC	9.140	Up-regulation
AGC_SGK_SGK1_ST	P49815	TSC2	O00141	SGK1	S1364	V1363M	1363	Missense	proximal	-1	no	10.900	10.973	EPSD	COSMIC	9.140	Up-regulation
AGC_SGK_SGK1_ST	P49815	TSC2	O00141	SGK1	S1364	R1361Q	1361	Missense	distal	-3	no	10.900	0.238	EPSD	COSMIC	9.140	Loss
AGC_SGK_SGK1_ST	P49815	TSC2	O00141	SGK1	S1364	G1367S	1367	Missense	distal	3	no	10.900	11.188	EPSD	COSMIC	9.140	Up-regulation
AGC_SGK_SGK1_ST	P49815	TSC2	O00141	SGK1	S1364	S1364F	1364	Missense	central	0	yes	10.900	0.000	EPSD	COSMIC	9.140	Loss
AGC_SGK_SGK1_ST	P49815	TSC2	O00141	SGK1	S1364	P1358H	1358	Missense	distal	-6	no	10.900	11.045	EPSD	COSMIC	9.140	Up-regulation
AGC_SGK_SGK1_ST	P49815	TSC2	O00141	SGK1	S1364	S1371R	1371	Missense	distal	7	no	10.900	10.951	EPSD	COSMIC	9.140	Up-regulation
AGC_SGK_SGK1_ST	P49815	TSC2	O00141	SGK1	S1364	S1364L	1364	Missense	central	0	yes	10.900	0.000	EPSD	COSMIC	9.140	Loss
AGC_SGK_SGK1_ST	P49815	TSC2	O00141	SGK1	S1388	S1383R	1383	Missense	distal	-5	no	5.983	11.228	EPSD	COSMIC	9.140	Gain
AGC_SGK_SGK1_ST	P49815	TSC2	O00141	SGK1	S1420	E1413D	1413	Missense	distal	-7	no	10.901	10.761	EPSD	COSMIC	9.140	Down-regulation
AGC_SGK_SGK1_ST	P49815	TSC2	O00141	SGK1	S1420	S1427R	1427	Missense	distal	7	no	10.901	10.952	EPSD	COSMIC	9.140	Up-regulation
AGC_SGK_SGK1_ST	P49815	TSC2	O00141	SGK1	S1420	S1420C	1420	Missense	central	0	yes	10.901	0.000	EPSD	COSMIC	9.140	Loss
AGC_SGK_SGK1_ST	P49815	TSC2	O00141	SGK1	T1422	A1429S	1429	Missense	distal	7	no	9.315	9.222	EPSD	COSMIC;GDSC	9.140	Down-regulation
AGC_SGK_SGK1_ST	P49815	TSC2	O00141	SGK1	T1422	A1429V	1429	Missense	distal	7	no	9.315	9.718	EPSD	COSMIC	9.140	Up-regulation
AGC_SGK_SGK1_ST	P49815	TSC2	O00141	SGK1	T1422	S1427R	1427	Missense	distal	5	no	9.315	9.301	EPSD	COSMIC	9.140	Down-regulation
AGC_SGK_SGK1_ST	P49815	TSC2	O00141	SGK1	T1422	S1420C	1420	Missense	proximal	-2	no	9.315	9.187	EPSD	COSMIC	9.140	Down-regulation
AGC_SGK_SGK1_ST	P49815	TSC2	O00141	SGK1	S1437	E1435K	1435	Missense	proximal	-2	no	10.740	11.038	EPSD	COSMIC;CCLE	9.140	Up-regulation
AGC_SGK_SGK1_ST	P49815	TSC2	O00141	SGK1	S1437	G1439D	1439	Missense	proximal	2	no	10.740	10.518	EPSD	COSMIC;GDSC	9.140	Down-regulation
AGC_SGK_SGK1_ST	P49815	TSC2	O00141	SGK1	S1437	S1433L	1433	Missense	distal	-4	no	10.740	10.020	EPSD	COSMIC	9.140	Down-regulation
AGC_SGK_SGK1_ST	P49815	TSC2	O00141	SGK1	S1437	S1431C	1431	Missense	distal	-6	no	10.740	10.633	EPSD	COSMIC	9.140	Down-regulation
AGC_SGK_SGK1_ST	P49815	TSC2	O00141	SGK1	S1437	P1441S	1441	Missense	distal	4	no	10.740	10.957	EPSD	COSMIC	9.140	Up-regulation
AGC_SGK_SGK1_ST	P49815	TSC2	O00141	SGK1	S1437	S1431N	1431	Missense	distal	-6	no	10.740	10.713	EPSD	COSMIC	9.140	Down-regulation
AGC_SGK_SGK1_ST	P49815	TSC2	O00141	SGK1	S1448	P1446S	1446	Missense	proximal	-2	no	8.916	9.403	EPSD	COSMIC	9.140	Gain
AGC_SGK_SGK1_ST	P49815	TSC2	O00141	SGK1	S1454	S1454N	1454	Missense	central	0	yes	10.461	0.000	EPSD	COSMIC	9.140	Loss
AGC_SGK_SGK1_ST	P49815	TSC2	O00141	SGK1	S1454	Y1461H	1461	Missense	distal	7	no	10.461	10.201	EPSD	COSMIC	9.140	Down-regulation
AGC_SGK_SGK1_ST	P49815	TSC2	O00141	SGK1	S1454	R1459Q	1459	Missense	distal	5	no	10.461	10.432	EPSD	COSMIC	9.140	Down-regulation
AGC_SGK_SGK1_ST	P49815	TSC2	O00141	SGK1	S1454	S1454G	1454	Missense	central	0	yes	10.461	0.000	EPSD	COSMIC	9.140	Loss
AGC_SGK_SGK1_ST	P49815	TSC2	O00141	SGK1	S1454	R1451I	1451	Missense	distal	-3	no	10.461	1.918	EPSD	COSMIC	9.140	Loss
AGC_SGK_SGK1_ST	P49815	TSC2	O00141	SGK1	T1462	S1464F	1464	Missense	proximal	2	no	18.725	19.339	PhosphoSitePlus;EPSD	COSMIC	9.140	Up-regulation
AGC_SGK_SGK1_ST	P49815	TSC2	O00141	SGK1	T1462	S1464Y	1464	Missense	proximal	2	no	18.725	18.989	PhosphoSitePlus;EPSD	COSMIC	9.140	Up-regulation
AGC_SGK_SGK1_ST	P49815	TSC2	O00141	SGK1	T1462	Y1461H	1461	Missense	proximal	-1	no	18.725	18.764	PhosphoSitePlus;EPSD	COSMIC	9.140	Up-regulation
AGC_SGK_SGK1_ST	P49815	TSC2	O00141	SGK1	T1462	R1459Q	1459	Missense	distal	-3	no	18.725	8.062	PhosphoSitePlus;EPSD	COSMIC	9.140	Loss
AGC_SGK_SGK1_ST	P49815	TSC2	O00141	SGK1	T1462	I1463N	1463	Missense	proximal	1	no	18.725	18.574	PhosphoSitePlus;EPSD	COSMIC	9.140	Down-regulation
AGC_SGK_SGK1_ST	P49815	TSC2	O00141	SGK1	T1462	D1465N	1465	Missense	distal	3	no	18.725	18.814	PhosphoSitePlus;EPSD	COSMIC	9.140	Up-regulation
AGC_SGK_SGK1_ST	P49815	TSC2	O00141	SGK1	T1462	P1468T	1468	Missense	distal	6	no	18.725	18.862	PhosphoSitePlus;EPSD	COSMIC	9.140	Up-regulation
AGC_SGK_SGK1_ST	P49815	TSC2	O00141	SGK1	T1462	T1462I	1462	Missense	central	0	yes	18.725	0.000	PhosphoSitePlus;EPSD	COSMIC	9.140	Loss
AGC_SGK_SGK1_ST	P49815	TSC2	O00141	SGK1	T1462	S1464C	1464	Missense	proximal	2	no	18.725	18.779	PhosphoSitePlus;EPSD	COSMIC	9.140	Up-regulation
AGC_SGK_SGK1_ST	P49815	TSC2	O00141	SGK1	S1464	S1464F	1464	Missense	central	0	yes	12.564	0.000	EPSD	COSMIC	9.140	Loss
AGC_SGK_SGK1_ST	P49815	TSC2	O00141	SGK1	S1464	S1464Y	1464	Missense	central	0	yes	12.564	0.000	EPSD	COSMIC	9.140	Loss
AGC_SGK_SGK1_ST	P49815	TSC2	O00141	SGK1	S1464	Y1461H	1461	Missense	distal	-3	no	12.564	8.412	EPSD	COSMIC	9.140	Loss
AGC_SGK_SGK1_ST	P49815	TSC2	O00141	SGK1	S1464	R1459Q	1459	Missense	distal	-5	no	12.564	4.413	EPSD	COSMIC	9.140	Loss
AGC_SGK_SGK1_ST	P49815	TSC2	O00141	SGK1	S1464	I1463N	1463	Missense	proximal	-1	no	12.564	12.680	EPSD	COSMIC	9.140	Up-regulation
AGC_SGK_SGK1_ST	P49815	TSC2	O00141	SGK1	S1464	R1471M	1471	Missense	distal	7	no	12.564	12.808	EPSD	COSMIC	9.140	Up-regulation
AGC_SGK_SGK1_ST	P49815	TSC2	O00141	SGK1	S1464	R1470H	1470	Missense	distal	6	no	12.564	12.531	EPSD	COSMIC	9.140	Down-regulation
AGC_SGK_SGK1_ST	P49815	TSC2	O00141	SGK1	S1464	D1465N	1465	Missense	proximal	1	no	12.564	12.433	EPSD	COSMIC	9.140	Down-regulation
AGC_SGK_SGK1_ST	P49815	TSC2	O00141	SGK1	S1464	P1468T	1468	Missense	distal	4	no	12.564	12.724	EPSD	COSMIC	9.140	Up-regulation
AGC_SGK_SGK1_ST	P49815	TSC2	O00141	SGK1	S1464	T1462I	1462	Missense	proximal	-2	no	12.564	12.249	EPSD	COSMIC	9.140	Down-regulation
AGC_SGK_SGK1_ST	P49815	TSC2	O00141	SGK1	S1464	S1464C	1464	Missense	central	0	yes	12.564	0.000	EPSD	COSMIC	9.140	Loss
AGC_SGK_SGK1_ST	P49815	TSC2	O00141	SGK1	S1798	R1795H	1795	Missense	distal	-3	no	18.412	8.793	EPSD;PhosphoSitePlus	COSMIC	9.140	Loss
AGC_SGK_SGK1_ST	P49815	TSC2	O00141	SGK1	S1798	R1793Q	1793	Missense	distal	-5	no	18.412	10.261	EPSD;PhosphoSitePlus	COSMIC	9.140	Down-regulation
AGC_SGK_SGK1_ST	P49815	TSC2	O00141	SGK1	S1798	R1795C	1795	Missense	distal	-3	no	18.412	10.350	EPSD;PhosphoSitePlus	COSMIC	9.140	Down-regulation
AGC_SGK_SGK1_ST	P49815	TSC2	O00141	SGK1	S1798	R1793W	1793	Missense	distal	-5	no	18.412	10.754	EPSD;PhosphoSitePlus	COSMIC	9.140	Down-regulation
AGC_SGK_SGK1_ST	P49815	TSC2	O00141	SGK1	S1798	G1791S	1791	Missense	distal	-7	no	18.412	17.547	EPSD;PhosphoSitePlus	COSMIC	9.140	Down-regulation
AGC_SGK_SGK1_ST	P49815	TSC2	O00141	SGK1	S1798	T1804I	1804	Missense	distal	6	no	18.412	18.221	EPSD;PhosphoSitePlus	COSMIC	9.140	Down-regulation
AGC_SGK_SGK1_ST	P49815	TSC2	O00141	SGK1	S1798	R1793H	1793	Missense	distal	-5	no	18.412	11.079	EPSD;PhosphoSitePlus	COSMIC	9.140	Down-regulation
AGC_SGK_SGK1_ST	P49815	TSC2	O00141	SGK1	S1798	R1793C	1793	Missense	distal	-5	no	18.412	12.150	EPSD;PhosphoSitePlus	COSMIC	9.140	Down-regulation
AGC_SGK_SGK1_ST	O60343	TBC1D4	O00141	SGK1	S133	L136I	136	Missense	distal	3	no	9.772	9.672	EPSD	COSMIC	9.140	Down-regulation
AGC_SGK_SGK1_ST	O60343	TBC1D4	O00141	SGK1	S304	E302K	302	Missense	proximal	-2	no	13.809	14.107	EPSD	COSMIC	9.140	Up-regulation
AGC_SGK_SGK1_ST	O60343	TBC1D4	O00141	SGK1	S318	G321S	321	Missense	distal	3	no	18.274	18.563	PhosphoSitePlus;EPSD	COSMIC;GDSC	9.140	Up-regulation
AGC_SGK_SGK1_ST	O60343	TBC1D4	O00141	SGK1	S318	R324W	324	Missense	distal	6	no	18.274	18.013	PhosphoSitePlus;EPSD	COSMIC	9.140	Down-regulation
AGC_SGK_SGK1_ST	O60343	TBC1D4	O00141	SGK1	S330	H327Y	327	Missense	distal	-3	no	6.389	10.541	EPSD	COSMIC	9.140	Gain
AGC_SGK_SGK1_ST	O60343	TBC1D4	O00141	SGK1	S341	P335L	335	Missense	distal	-6	no	18.973	19.055	EPSD;PhosphoSitePlus	COSMIC	9.140	Up-regulation
AGC_SGK_SGK1_ST	O60343	TBC1D4	O00141	SGK1	S341	S344C	344	Missense	distal	3	no	18.973	18.792	EPSD;PhosphoSitePlus	COSMIC	9.140	Down-regulation
AGC_SGK_SGK1_ST	O60343	TBC1D4	O00141	SGK1	S445	T448M	448	Missense	distal	3	no	9.160	9.020	EPSD	COSMIC	9.140	Loss
AGC_SGK_SGK1_ST	O60343	TBC1D4	O00141	SGK1	S570	R577M	577	Missense	distal	7	no	11.123	11.367	EPSD;PhosphoSitePlus	COSMIC	9.140	Up-regulation
AGC_SGK_SGK1_ST	O60343	TBC1D4	O00141	SGK1	S621	P618R	618	Missense	distal	-3	no	1.852	13.950	EPSD	COSMIC	9.140	Gain
AGC_SGK_SGK1_ST	O60343	TBC1D4	O00141	SGK1	S666	Q662L	662	Missense	distal	-4	no	10.493	10.540	EPSD;PhosphoSitePlus	COSMIC	9.140	Up-regulation
AGC_SGK_SGK1_ST	O60343	TBC1D4	O00141	SGK1	T701	T701N	701	Missense	central	0	yes	9.540	0.000	EPSD	COSMIC	9.140	Loss
AGC_SGK_SGK1_ST	O60343	TBC1D4	O00141	SGK1	T701	L699F	699	Missense	proximal	-2	no	9.540	8.810	EPSD	COSMIC	9.140	Loss
AGC_SGK_SGK1_ST	O60343	TBC1D4	O00141	SGK1	T701	P697L	697	Missense	distal	-4	no	9.540	9.831	EPSD	COSMIC	9.140	Up-regulation
AGC_SGK_SGK1_ST	O60343	TBC1D4	O00141	SGK1	S704	T701N	701	Missense	distal	-3	no	12.441	8.706	EPSD	COSMIC	9.140	Loss
AGC_SGK_SGK1_ST	O60343	TBC1D4	O00141	SGK1	S704	L699F	699	Missense	distal	-5	no	12.441	8.668	EPSD	COSMIC	9.140	Loss
AGC_SGK_SGK1_ST	O60343	TBC1D4	O00141	SGK1	S704	A710T	710	Missense	distal	6	no	12.441	12.383	EPSD	COSMIC	9.140	Down-regulation
AGC_SGK_SGK1_ST	O60343	TBC1D4	O00141	SGK1	S704	A710S	710	Missense	distal	6	no	12.441	12.447	EPSD	COSMIC	9.140	Up-regulation
AGC_SGK_SGK1_ST	O60343	TBC1D4	O00141	SGK1	S704	P697L	697	Missense	distal	-7	no	12.441	12.196	EPSD	COSMIC	9.140	Down-regulation
AGC_SGK_SGK1_ST	O60343	TBC1D4	O00141	SGK1	S751	L758I	758	Missense	distal	7	no	20.327	20.405	EPSD;PhosphoSitePlus	COSMIC	9.140	Up-regulation
AGC_SGK_SGK1_ST	O60343	TBC1D4	O00141	SGK1	T752	L758I	758	Missense	distal	6	no	10.075	9.934	EPSD	COSMIC	9.140	Down-regulation
AGC_SGK_SGK1_ST	O60343	TBC1D4	O00141	SGK1	S771	R773Q	773	Missense	proximal	2	no	10.734	10.514	EPSD	COSMIC	9.140	Down-regulation
AGC_SGK_SGK1_ST	O60343	TBC1D4	O00141	SGK1	S771	R775H	775	Missense	distal	4	no	10.734	10.763	EPSD	COSMIC	9.140	Up-regulation
AGC_SGK_SGK1_ST	O60343	TBC1D4	O00141	SGK1	S782	S787A	787	Missense	distal	5	no	10.278	10.269	EPSD	COSMIC	9.140	Down-regulation
AGC_SGK_SGK1_ST	O60343	TBC1D4	O00141	SGK1	S782	A781D	781	Missense	proximal	-1	no	10.278	10.160	EPSD	COSMIC	9.140	Down-regulation
AGC_SGK_SGK1_ST	O60343	TBC1D4	O00141	SGK1	S782	P783A	783	Missense	proximal	1	no	10.278	10.121	EPSD	COSMIC	9.140	Down-regulation
AGC_SGK_SGK1_ST	O60343	TBC1D4	O00141	SGK1	S782	R775H	775	Missense	distal	-7	no	10.278	10.572	EPSD	COSMIC	9.140	Up-regulation
AGC_SGK_SGK1_ST	O60343	TBC1D4	O00141	SGK1	S1126	L1123R	1123	Missense	distal	-3	no	6.729	12.077	EPSD	COSMIC;GDSC;CCLE	9.140	Gain
AGC_SGK_SGK1_ST	O60343	TBC1D4	O00141	SGK1	S1126	L1121R	1121	Missense	distal	-5	no	6.729	10.957	EPSD	COSMIC	9.140	Gain
AGC_SGK_SGK1_ST	O60343	TBC1D4	O00141	SGK1	S1207	A1205T	1205	Missense	proximal	-2	no	15.589	15.421	EPSD	COSMIC	9.140	Down-regulation
AGC_SGK_SGK1_ST	Q9UN36	NDRG2	O00141	SGK1	S328	S328F	328	Missense	central	0	yes	9.840	0.000	EPSD	COSMIC	9.140	Loss
AGC_SGK_SGK1_ST	Q9UN36	NDRG2	O00141	SGK1	S328	S332F	332	Missense	distal	4	no	9.840	9.396	EPSD	COSMIC	9.140	Down-regulation
AGC_SGK_SGK1_ST	Q9UN36	NDRG2	O00141	SGK1	S328	A331S	331	Missense	distal	3	no	9.840	9.893	EPSD	COSMIC	9.140	Up-regulation
AGC_SGK_SGK1_ST	Q9UN36	NDRG2	O00141	SGK1	S328	L325M	325	Missense	distal	-3	no	9.840	5.647	EPSD	COSMIC	9.140	Loss
AGC_SGK_SGK1_ST	Q9UN36	NDRG2	O00141	SGK1	S328	R324C	324	Missense	distal	-4	no	9.840	9.653	EPSD	COSMIC	9.140	Down-regulation
AGC_SGK_SGK1_ST	Q9UN36	NDRG2	O00141	SGK1	T330	S328F	328	Missense	proximal	-2	no	17.630	16.788	EPSD;PhosphoSitePlus	COSMIC	9.140	Down-regulation
AGC_SGK_SGK1_ST	Q9UN36	NDRG2	O00141	SGK1	T330	S332F	332	Missense	proximal	2	no	17.630	18.245	EPSD;PhosphoSitePlus	COSMIC	9.140	Up-regulation
AGC_SGK_SGK1_ST	Q9UN36	NDRG2	O00141	SGK1	T330	A331S	331	Missense	proximal	1	no	17.630	17.675	EPSD;PhosphoSitePlus	COSMIC	9.140	Up-regulation
AGC_SGK_SGK1_ST	Q9UN36	NDRG2	O00141	SGK1	T330	L325M	325	Missense	distal	-5	no	17.630	14.471	EPSD;PhosphoSitePlus	COSMIC	9.140	Down-regulation
AGC_SGK_SGK1_ST	Q9UN36	NDRG2	O00141	SGK1	T330	R324C	324	Missense	distal	-6	no	17.630	17.565	EPSD;PhosphoSitePlus	COSMIC	9.140	Down-regulation
AGC_SGK_SGK1_ST	Q9UN36	NDRG2	O00141	SGK1	T330	A337E	337	Missense	distal	7	no	17.630	17.848	EPSD;PhosphoSitePlus	COSMIC	9.140	Up-regulation
AGC_SGK_SGK1_ST	Q9UN36	NDRG2	O00141	SGK1	S332	S328F	328	Missense	distal	-4	no	20.303	18.128	EPSD;PhosphoSitePlus	COSMIC	9.140	Down-regulation
AGC_SGK_SGK1_ST	Q9UN36	NDRG2	O00141	SGK1	S332	S338G	338	Missense	distal	6	no	20.303	20.060	EPSD;PhosphoSitePlus	COSMIC	9.140	Down-regulation
AGC_SGK_SGK1_ST	Q9UN36	NDRG2	O00141	SGK1	S332	S332F	332	Missense	central	0	yes	20.303	0.000	EPSD;PhosphoSitePlus	COSMIC	9.140	Loss
AGC_SGK_SGK1_ST	Q9UN36	NDRG2	O00141	SGK1	S332	A331S	331	Missense	proximal	-1	no	20.303	20.338	EPSD;PhosphoSitePlus	COSMIC	9.140	Up-regulation
AGC_SGK_SGK1_ST	Q9UN36	NDRG2	O00141	SGK1	S332	L325M	325	Missense	distal	-7	no	20.303	20.323	EPSD;PhosphoSitePlus	COSMIC	9.140	Up-regulation
AGC_SGK_SGK1_ST	Q9UN36	NDRG2	O00141	SGK1	S332	A337E	337	Missense	distal	5	no	20.303	20.271	EPSD;PhosphoSitePlus	COSMIC	9.140	Down-regulation
AGC_SGK_SGK1_ST	Q9UN36	NDRG2	O00141	SGK1	T334	S328F	328	Missense	distal	-6	no	13.398	12.873	EPSD	COSMIC	9.140	Down-regulation
AGC_SGK_SGK1_ST	Q9UN36	NDRG2	O00141	SGK1	T334	S338G	338	Missense	distal	4	no	13.398	13.166	EPSD	COSMIC	9.140	Down-regulation
AGC_SGK_SGK1_ST	Q9UN36	NDRG2	O00141	SGK1	T334	S332F	332	Missense	proximal	-2	no	13.398	12.556	EPSD	COSMIC	9.140	Down-regulation
AGC_SGK_SGK1_ST	Q9UN36	NDRG2	O00141	SGK1	T334	A331S	331	Missense	distal	-3	no	13.398	11.779	EPSD	COSMIC	9.140	Down-regulation
AGC_SGK_SGK1_ST	Q9UN36	NDRG2	O00141	SGK1	T334	A337E	337	Missense	distal	3	no	13.398	13.145	EPSD	COSMIC	9.140	Down-regulation
AGC_SGK_SGK1_ST	Q9UN36	NDRG2	O00141	SGK1	S346	L349M	349	Missense	distal	3	no	14.496	14.568	EPSD;PhosphoSitePlus	COSMIC	9.140	Up-regulation
AGC_SGK_SGK1_ST	Q9UN36	NDRG2	O00141	SGK1	S346	S353G	353	Missense	distal	7	no	14.496	14.881	EPSD;PhosphoSitePlus	COSMIC	9.140	Up-regulation
AGC_SGK_SGK1_ST	Q9UN36	NDRG2	O00141	SGK1	S346	R345L	345	Missense	proximal	-1	no	14.496	14.382	EPSD;PhosphoSitePlus	COSMIC	9.140	Down-regulation
AGC_SGK_SGK1_ST	Q9UN36	NDRG2	O00141	SGK1	T348	S355F	355	Missense	distal	7	no	19.728	20.412	PhosphoSitePlus;EPSD	COSMIC	9.140	Up-regulation
AGC_SGK_SGK1_ST	Q9UN36	NDRG2	O00141	SGK1	T348	L349M	349	Missense	proximal	1	no	19.728	19.736	PhosphoSitePlus;EPSD	COSMIC	9.140	Up-regulation
AGC_SGK_SGK1_ST	Q9UN36	NDRG2	O00141	SGK1	T348	S353G	353	Missense	distal	5	no	19.728	19.675	PhosphoSitePlus;EPSD	COSMIC	9.140	Down-regulation
AGC_SGK_SGK1_ST	Q9UN36	NDRG2	O00141	SGK1	T348	R345L	345	Missense	distal	-3	no	19.728	14.379	PhosphoSitePlus;EPSD	COSMIC	9.140	Down-regulation
AGC_SGK_SGK1_ST	Q9UN36	NDRG2	O00141	SGK1	S350	S355F	355	Missense	distal	5	no	16.482	16.357	EPSD	COSMIC	9.140	Down-regulation
AGC_SGK_SGK1_ST	Q9UN36	NDRG2	O00141	SGK1	S350	L349M	349	Missense	proximal	-1	no	16.482	16.425	EPSD	COSMIC	9.140	Down-regulation
AGC_SGK_SGK1_ST	Q9UN36	NDRG2	O00141	SGK1	S350	S353G	353	Missense	distal	3	no	16.482	16.194	EPSD	COSMIC	9.140	Down-regulation
AGC_SGK_SGK1_ST	Q9UN36	NDRG2	O00141	SGK1	S350	R345L	345	Missense	distal	-5	no	16.482	12.254	EPSD	COSMIC	9.140	Down-regulation
AGC_SGK_SGK1_ST	Q9UN36	NDRG2	O00141	SGK1	S352	S359F	359	Missense	distal	7	no	9.627	10.311	EPSD	COSMIC	9.140	Up-regulation
AGC_SGK_SGK1_ST	Q9UN36	NDRG2	O00141	SGK1	S352	S355F	355	Missense	distal	3	no	9.627	8.821	EPSD	COSMIC	9.140	Loss
AGC_SGK_SGK1_ST	Q9UN36	NDRG2	O00141	SGK1	S352	L349M	349	Missense	distal	-3	no	9.627	5.435	EPSD	COSMIC	9.140	Loss
AGC_SGK_SGK1_ST	Q9UN36	NDRG2	O00141	SGK1	S352	S353G	353	Missense	proximal	1	no	9.627	9.818	EPSD	COSMIC	9.140	Up-regulation
AGC_SGK_SGK1_ST	Q9UN36	NDRG2	O00141	SGK1	S352	R345L	345	Missense	distal	-7	no	9.627	10.308	EPSD	COSMIC	9.140	Up-regulation
AGC_SGK_SGK1_ST	P16220	CREB1	O00141	SGK1	S98	S103N	103	Missense	distal	5	no	16.107	16.089	EPSD	COSMIC	9.140	Down-regulation
AGC_SGK_SGK1_ST	P16220	CREB1	O00141	SGK1	S98	R95I	95	Missense	distal	-3	no	16.107	7.564	EPSD	COSMIC	9.140	Loss
AGC_SGK_SGK1_ST	P16220	CREB1	O00141	SGK1	S98	I102M	102	Missense	distal	4	no	16.107	16.169	EPSD	COSMIC	9.140	Up-regulation
AGC_SGK_SGK1_ST	P16220	CREB1	O00141	SGK1	T100	S103N	103	Missense	distal	3	no	9.864	9.736	EPSD	COSMIC	9.140	Down-regulation
AGC_SGK_SGK1_ST	P16220	CREB1	O00141	SGK1	T100	R95I	95	Missense	distal	-5	no	9.864	3.223	EPSD	COSMIC	9.140	Loss
AGC_SGK_SGK1_ST	P16220	CREB1	O00141	SGK1	T100	I102M	102	Missense	proximal	2	no	9.864	9.750	EPSD	COSMIC	9.140	Down-regulation
AGC_SGK_SGK1_ST	P16220	CREB1	O00141	SGK1	S133	L128R	128	Missense	distal	-5	no	15.615	19.843	PhosphoSitePlus	COSMIC	9.140	Up-regulation
AGC_SGK_SGK1_ST	P16220	CREB1	O00141	SGK1	S260	I262V	262	Missense	proximal	2	no	11.725	11.699	EPSD	COSMIC	9.140	Down-regulation
AGC_SGK_SGK1_ST	P16220	CREB1	O00141	SGK1	S260	R255H	255	Missense	distal	-5	no	11.725	4.393	EPSD	COSMIC	9.140	Loss
AGC_SGK_SGK1_ST	P16220	CREB1	O00141	SGK1	S260	A257T	257	Missense	distal	-3	no	11.725	11.664	EPSD	COSMIC	9.140	Down-regulation
AGC_SGK_SGK1_ST	P16220	CREB1	O00141	SGK1	S260	P264T	264	Missense	distal	4	no	11.725	11.886	EPSD	COSMIC;GDSC;CCLE	9.140	Up-regulation
AGC_SGK_SGK1_ST	P10636	MAPT	O00141	SGK1	T167	P160Q	160	Missense	distal	-7	no	10.219	9.821	EPSD	COSMIC	9.140	Down-regulation
AGC_SGK_SGK1_ST	P10636	MAPT	O00141	SGK1	T167	A166V	166	Missense	proximal	-1	no	10.219	10.034	EPSD	COSMIC;CCLE	9.140	Down-regulation
AGC_SGK_SGK1_ST	P10636	MAPT	O00141	SGK1	T167	E165K	165	Missense	proximal	-2	no	10.219	10.517	EPSD	COSMIC	9.140	Up-regulation
AGC_SGK_SGK1_ST	P10636	MAPT	O00141	SGK1	T167	P160S	160	Missense	distal	-7	no	10.219	9.315	EPSD	COSMIC	9.140	Down-regulation
AGC_SGK_SGK1_ST	P10636	MAPT	O00141	SGK1	T167	G172V	172	Missense	distal	5	no	10.219	10.182	EPSD	COSMIC	9.140	Down-regulation
AGC_SGK_SGK1_ST	P10636	MAPT	O00141	SGK1	S171	P175S	175	Missense	distal	4	no	12.821	13.038	EPSD	COSMIC	9.140	Up-regulation
AGC_SGK_SGK1_ST	P10636	MAPT	O00141	SGK1	S171	A166V	166	Missense	distal	-5	no	12.821	7.759	EPSD	COSMIC;CCLE	9.140	Loss
AGC_SGK_SGK1_ST	P10636	MAPT	O00141	SGK1	S171	E176G	176	Missense	distal	5	no	12.821	12.810	EPSD	COSMIC	9.140	Down-regulation
AGC_SGK_SGK1_ST	P10636	MAPT	O00141	SGK1	S171	D177G	177	Missense	distal	6	no	12.821	12.711	EPSD	COSMIC	9.140	Down-regulation
AGC_SGK_SGK1_ST	P10636	MAPT	O00141	SGK1	S171	E165K	165	Missense	distal	-6	no	12.821	13.115	EPSD	COSMIC	9.140	Up-regulation
AGC_SGK_SGK1_ST	P10636	MAPT	O00141	SGK1	S171	G172V	172	Missense	proximal	1	no	12.821	12.756	EPSD	COSMIC	9.140	Down-regulation
AGC_SGK_SGK1_ST	P10636	MAPT	O00141	SGK1	S214	E210Q	210	Missense	distal	-4	no	13.460	13.368	PhosphoSitePlus	COSMIC	9.140	Down-regulation
AGC_SGK_SGK1_ST	P10636	MAPT	O00141	SGK1	S214	G207E	207	Missense	distal	-7	no	13.460	13.307	PhosphoSitePlus	COSMIC	9.140	Down-regulation
AGC_SGK_SGK1_ST	P10636	MAPT	O00141	SGK1	S235	Q230R	230	Missense	distal	-5	no	2.412	10.563	EPSD	COSMIC	9.140	Gain
AGC_SGK_SGK1_ST	P10636	MAPT	O00141	SGK1	S341	A337T	337	Missense	distal	-4	no	9.968	9.555	EPSD	COSMIC	9.140	Down-regulation
AGC_SGK_SGK1_ST	P10636	MAPT	O00141	SGK1	S341	G343R	343	Missense	proximal	2	no	9.968	9.941	EPSD	COSMIC	9.140	Down-regulation
AGC_SGK_SGK1_ST	P10636	MAPT	O00141	SGK1	S341	D345G	345	Missense	distal	4	no	9.968	9.830	EPSD	COSMIC	9.140	Down-regulation
AGC_SGK_SGK1_ST	P10636	MAPT	O00141	SGK1	S341	K347N	347	Missense	distal	6	no	9.968	9.834	EPSD	COSMIC	9.140	Down-regulation
AGC_SGK_SGK1_ST	P10636	MAPT	O00141	SGK1	S369	V368I	368	Missense	proximal	-1	no	11.179	11.222	EPSD	COSMIC	9.140	Up-regulation
AGC_SGK_SGK1_ST	P10636	MAPT	O00141	SGK1	S369	R370W	370	Missense	proximal	1	no	11.179	11.332	EPSD	COSMIC	9.140	Up-regulation
AGC_SGK_SGK1_ST	P10636	MAPT	O00141	SGK1	S388	G385V	385	Missense	distal	-3	no	10.775	5.612	EPSD	COSMIC	9.140	Loss
AGC_SGK_SGK1_ST	P10636	MAPT	O00141	SGK1	S388	T386I	386	Missense	proximal	-2	no	10.775	10.460	EPSD	COSMIC	9.140	Down-regulation
AGC_SGK_SGK1_ST	P10636	MAPT	O00141	SGK1	S388	D389N	389	Missense	proximal	1	no	10.775	10.644	EPSD	COSMIC;GDSC;CCLE	9.140	Down-regulation
AGC_SGK_SGK1_ST	P10636	MAPT	O00141	SGK1	S400	R398C	398	Missense	proximal	-2	no	9.501	9.276	EPSD	COSMIC	9.140	Down-regulation
AGC_SGK_SGK1_ST	P10636	MAPT	O00141	SGK1	S400	S396F	396	Missense	distal	-4	no	9.501	7.326	EPSD	COSMIC	9.140	Loss
AGC_SGK_SGK1_ST	P10636	MAPT	O00141	SGK1	T403	L410F	410	Missense	distal	7	no	10.858	11.201	EPSD	COSMIC	9.140	Up-regulation
AGC_SGK_SGK1_ST	P10636	MAPT	O00141	SGK1	T403	R398C	398	Missense	distal	-5	no	10.858	4.596	EPSD	COSMIC	9.140	Loss
AGC_SGK_SGK1_ST	P10636	MAPT	O00141	SGK1	T403	S396F	396	Missense	distal	-7	no	10.858	12.297	EPSD	COSMIC	9.140	Up-regulation
AGC_SGK_SGK1_ST	P10636	MAPT	O00141	SGK1	S451	S447P	447	Missense	distal	-4	no	16.146	15.135	EPSD	COSMIC	9.140	Down-regulation
AGC_SGK_SGK1_ST	P10636	MAPT	O00141	SGK1	S451	R448Q	448	Missense	distal	-3	no	16.146	5.484	EPSD	COSMIC	9.140	Loss
AGC_SGK_SGK1_ST	P10636	MAPT	O00141	SGK1	T486	R487K	487	Missense	proximal	1	no	9.480	9.330	EPSD	COSMIC	9.140	Down-regulation
AGC_SGK_SGK1_ST	P10636	MAPT	O00141	SGK1	T486	K491R	491	Missense	distal	5	no	9.480	9.448	EPSD	COSMIC	9.140	Down-regulation
AGC_SGK_SGK1_ST	P10636	MAPT	O00141	SGK1	T486	R487G	487	Missense	proximal	1	no	9.480	9.658	EPSD	COSMIC	9.140	Up-regulation
AGC_SGK_SGK1_ST	P10636	MAPT	O00141	SGK1	T486	P493L	493	Missense	distal	7	no	9.480	9.429	EPSD	COSMIC	9.140	Down-regulation
AGC_SGK_SGK1_ST	P10636	MAPT	O00141	SGK1	S516	G521V	521	Missense	distal	5	no	12.537	12.500	EPSD	COSMIC	9.140	Down-regulation
AGC_SGK_SGK1_ST	P10636	MAPT	O00141	SGK1	S516	G518V	518	Missense	proximal	2	no	12.537	12.611	EPSD	COSMIC	9.140	Up-regulation
AGC_SGK_SGK1_ST	P10636	MAPT	O00141	SGK1	S516	R511C	511	Missense	distal	-5	no	12.537	6.275	EPSD	COSMIC;CCLE	9.140	Loss
AGC_SGK_SGK1_ST	P10636	MAPT	O00141	SGK1	S516	G509V	509	Missense	distal	-7	no	12.537	12.819	EPSD	COSMIC	9.140	Up-regulation
AGC_SGK_SGK1_ST	P10636	MAPT	O00141	SGK1	T529	R526H	526	Missense	distal	-3	no	11.727	2.108	EPSD	COSMIC	9.140	Loss
AGC_SGK_SGK1_ST	P10636	MAPT	O00141	SGK1	T529	R528S	528	Missense	proximal	-1	no	11.727	11.703	EPSD	COSMIC	9.140	Down-regulation
AGC_SGK_SGK1_ST	P10636	MAPT	O00141	SGK1	T529	P530S	530	Missense	proximal	1	no	11.727	11.615	EPSD	COSMIC	9.140	Down-regulation
AGC_SGK_SGK1_ST	P10636	MAPT	O00141	SGK1	T529	P536H	536	Missense	distal	7	no	11.727	11.469	EPSD	COSMIC	9.140	Down-regulation
AGC_SGK_SGK1_ST	P10636	MAPT	O00141	SGK1	T529	P535Q	535	Missense	distal	6	no	11.727	11.792	EPSD	COSMIC	9.140	Up-regulation
AGC_SGK_SGK1_ST	P10636	MAPT	O00141	SGK1	S531	R526H	526	Missense	distal	-5	no	17.834	10.502	EPSD	COSMIC	9.140	Down-regulation
AGC_SGK_SGK1_ST	P10636	MAPT	O00141	SGK1	S531	R528S	528	Missense	distal	-3	no	17.834	10.929	EPSD	COSMIC	9.140	Down-regulation
AGC_SGK_SGK1_ST	P10636	MAPT	O00141	SGK1	S531	P530S	530	Missense	proximal	-1	no	17.834	18.028	EPSD	COSMIC	9.140	Up-regulation
AGC_SGK_SGK1_ST	P10636	MAPT	O00141	SGK1	S531	P536H	536	Missense	distal	5	no	17.834	17.867	EPSD	COSMIC	9.140	Up-regulation
AGC_SGK_SGK1_ST	P10636	MAPT	O00141	SGK1	S531	P535Q	535	Missense	distal	4	no	17.834	17.940	EPSD	COSMIC	9.140	Up-regulation
AGC_SGK_SGK1_ST	P10636	MAPT	O00141	SGK1	S552	P549L	549	Missense	distal	-3	no	5.715	12.464	EPSD	COSMIC	9.140	Gain
AGC_SGK_SGK1_ST	P10636	MAPT	O00141	SGK1	T562	V565M	565	Missense	distal	3	no	11.032	11.340	EPSD	COSMIC	9.140	Up-regulation
AGC_SGK_SGK1_ST	P10636	MAPT	O00141	SGK1	T562	P566S	566	Missense	distal	4	no	11.032	11.249	EPSD	COSMIC	9.140	Up-regulation
AGC_SGK_SGK1_ST	P10636	MAPT	O00141	SGK1	T562	R559C	559	Missense	distal	-3	no	11.032	2.970	EPSD	COSMIC	9.140	Loss
AGC_SGK_SGK1_ST	P10636	MAPT	O00141	SGK1	T562	S555F	555	Missense	distal	-7	no	11.032	12.471	EPSD	COSMIC	9.140	Up-regulation
AGC_SGK_SGK1_ST	P10636	MAPT	O00141	SGK1	T562	P568S	568	Missense	distal	6	no	11.032	11.234	EPSD	COSMIC	9.140	Up-regulation
AGC_SGK_SGK1_ST	P10636	MAPT	O00141	SGK1	S602	S602G	602	Missense	central	0	yes	12.280	0.000	EPSD	COSMIC	9.140	Loss
AGC_SGK_SGK1_ST	P10636	MAPT	O00141	SGK1	S602	I595L	595	Missense	distal	-7	no	12.280	12.032	EPSD	COSMIC	9.140	Down-regulation
AGC_SGK_SGK1_ST	P10636	MAPT	O00141	SGK1	S602	K598T	598	Missense	distal	-4	no	12.280	11.876	EPSD	COSMIC	9.140	Down-regulation
AGC_SGK_SGK1_ST	P10636	MAPT	O00141	SGK1	S602	C608W	608	Missense	distal	6	no	12.280	12.031	EPSD	COSMIC	9.140	Down-regulation
AGC_SGK_SGK1_ST	P10636	MAPT	O00141	SGK1	S602	D600E	600	Missense	proximal	-2	no	12.280	12.177	EPSD	COSMIC	9.140	Down-regulation
AGC_SGK_SGK1_ST	P10636	MAPT	O00141	SGK1	S669	S669L	669	Missense	central	0	yes	10.428	0.000	EPSD	COSMIC	9.140	Loss
AGC_SGK_SGK1_ST	P10636	MAPT	O00141	SGK1	S669	R666K	666	Missense	distal	-3	no	10.428	4.342	EPSD	COSMIC	9.140	Loss
AGC_SGK_SGK1_ST	P10636	MAPT	O00141	SGK1	S669	D662G	662	Missense	distal	-7	no	10.428	10.722	EPSD	COSMIC	9.140	Up-regulation
AGC_SGK_SGK1_ST	P10636	MAPT	O00141	SGK1	S669	S673F	673	Missense	distal	4	no	10.428	9.985	EPSD	COSMIC	9.140	Down-regulation
AGC_SGK_SGK1_ST	P10636	MAPT	O00141	SGK1	S669	K670N	670	Missense	proximal	1	no	10.428	10.519	EPSD	COSMIC	9.140	Up-regulation
AGC_SGK_SGK1_ST	P10636	MAPT	O00141	SGK1	S669	K664N	664	Missense	distal	-5	no	10.428	8.208	EPSD	COSMIC	9.140	Loss
AGC_SGK_SGK1_ST	P10636	MAPT	O00141	SGK1	S726	G732S	732	Missense	distal	6	no	13.118	13.361	EPSD	COSMIC	9.140	Up-regulation
AGC_SGK_SGK1_ST	P10636	MAPT	O00141	SGK1	S726	G732C	732	Missense	distal	6	no	13.118	13.291	EPSD	COSMIC	9.140	Up-regulation
AGC_SGK_SGK1_ST	P10636	MAPT	O00141	SGK1	S726	R723W	723	Missense	distal	-3	no	13.118	3.423	EPSD	COSMIC	9.140	Loss
AGC_SGK_SGK1_ST	P10636	MAPT	O00141	SGK1	S726	V728M	728	Missense	proximal	2	no	13.118	13.030	EPSD	COSMIC	9.140	Down-regulation
AGC_SGK_SGK1_ST	P10636	MAPT	O00141	SGK1	S726	V728A	728	Missense	proximal	2	no	13.118	12.776	EPSD	COSMIC	9.140	Down-regulation
AGC_SGK_SGK1_ST	Q92542	NCSTN	O00141	SGK1	S437	R432Q	432	Missense	distal	-5	no	18.479	10.328	PhosphoSitePlus	COSMIC	9.140	Down-regulation
AGC_SGK_SGK1_ST	Q92542	NCSTN	O00141	SGK1	S632	A625S	625	Missense	distal	-7	no	13.327	13.151	EPSD	COSMIC	9.140	Down-regulation
AGC_SGK_SGK1_ST	Q92542	NCSTN	O00141	SGK1	S632	R626Q	626	Missense	distal	-6	no	13.327	13.207	EPSD	COSMIC	9.140	Down-regulation
AGC_SGK_SGK1_ST	P46527	CDKN1B	O00141	SGK1	S110	Q107R	107	Missense	distal	-3	no	-0.511	10.151	EPSD	COSMIC	9.140	Gain
AGC_SGK_SGK1_ST	P46527	CDKN1B	O00141	SGK1	S138	P133T	133	Missense	distal	-5	no	6.619	11.852	EPSD	COSMIC	9.140	Gain
AGC_SGK_SGK1_ST	P46527	CDKN1B	O00141	SGK1	T157	A156V	156	Missense	proximal	-1	no	16.770	16.584	PhosphoSitePlus;EPSD	COSMIC	9.140	Down-regulation
AGC_SGK_SGK1_ST	P46527	CDKN1B	O00141	SGK1	T157	D158Y	158	Missense	proximal	1	no	16.770	16.779	PhosphoSitePlus;EPSD	COSMIC	9.140	Up-regulation
AGC_SGK_SGK1_ST	P46527	CDKN1B	O00141	SGK1	T157	T157N	157	Missense	central	0	yes	16.770	0.000	PhosphoSitePlus;EPSD	COSMIC	9.140	Loss
AGC_SGK_SGK1_ST	P46527	CDKN1B	O00141	SGK1	T157	D159Y	159	Missense	proximal	2	no	16.770	16.930	PhosphoSitePlus;EPSD	COSMIC	9.140	Up-regulation
AGC_SGK_SGK1_ST	P46527	CDKN1B	O00141	SGK1	T157	S161F	161	Missense	distal	4	no	16.770	16.326	PhosphoSitePlus;EPSD	COSMIC	9.140	Down-regulation
AGC_SGK_SGK1_ST	P46527	CDKN1B	O00141	SGK1	T198	R194K	194	Missense	distal	-4	no	12.359	12.540	EPSD;PhosphoSitePlus	COSMIC	9.140	Up-regulation
AGC_SGK_SGK1_ST	Q9Y2V2	CARHSP1	O00141	SGK1	S26	R29C	29	Missense	distal	3	no	9.859	9.797	EPSD	COSMIC	9.140	Down-regulation
AGC_SGK_SGK1_ST	Q9Y2V2	CARHSP1	O00141	SGK1	S26	P33S	33	Missense	distal	7	no	9.859	9.466	EPSD	COSMIC	9.140	Down-regulation
AGC_SGK_SGK1_ST	Q9Y2V2	CARHSP1	O00141	SGK1	S26	G19R	19	Missense	distal	-7	no	9.859	8.972	EPSD	COSMIC	9.140	Loss
AGC_SGK_SGK1_ST	Q9Y2V2	CARHSP1	O00141	SGK1	S30	R35W	35	Missense	distal	5	no	19.261	19.181	EPSD	COSMIC	9.140	Down-regulation
AGC_SGK_SGK1_ST	Q9Y2V2	CARHSP1	O00141	SGK1	S30	R29C	29	Missense	proximal	-1	no	19.261	19.141	EPSD	COSMIC	9.140	Down-regulation
AGC_SGK_SGK1_ST	Q9Y2V2	CARHSP1	O00141	SGK1	S30	P33S	33	Missense	distal	3	no	19.261	19.657	EPSD	COSMIC	9.140	Up-regulation
AGC_SGK_SGK1_ST	Q9Y2V2	CARHSP1	O00141	SGK1	S32	V39A	39	Missense	distal	7	no	17.475	17.072	EPSD	COSMIC	9.140	Down-regulation
AGC_SGK_SGK1_ST	Q9Y2V2	CARHSP1	O00141	SGK1	S32	R35W	35	Missense	distal	3	no	17.475	16.993	EPSD	COSMIC	9.140	Down-regulation
AGC_SGK_SGK1_ST	Q9Y2V2	CARHSP1	O00141	SGK1	S32	R29C	29	Missense	distal	-3	no	17.475	9.413	EPSD	COSMIC	9.140	Down-regulation
AGC_SGK_SGK1_ST	Q9Y2V2	CARHSP1	O00141	SGK1	S32	P33S	33	Missense	proximal	1	no	17.475	17.363	EPSD	COSMIC	9.140	Down-regulation
AGC_SGK_SGK1_ST	Q9Y2V2	CARHSP1	O00141	SGK1	T50	R46H	46	Missense	distal	-4	no	12.625	12.207	EPSD	COSMIC	9.140	Down-regulation
AGC_SGK_SGK1_ST	Q9Y2V2	CARHSP1	O00141	SGK1	S52	R46H	46	Missense	distal	-6	no	16.115	16.033	PhosphoSitePlus	COSMIC	9.140	Down-regulation
AGC_SGK_SGK1_ST	Q9H4A3	WNK1	O00141	SGK1	T60	R58Q	58	Missense	proximal	-2	no	16.959	16.506	PhosphoSitePlus	COSMIC	9.140	Down-regulation
AGC_SGK_SGK1_ST	Q9H4A3	WNK1	O00141	SGK1	S167	S167F	167	Missense	central	0	yes	13.383	0.000	EPSD	COSMIC	9.140	Loss
AGC_SGK_SGK1_ST	Q9H4A3	WNK1	O00141	SGK1	S167	V166L	166	Missense	proximal	-1	no	13.383	13.513	EPSD	COSMIC	9.140	Up-regulation
AGC_SGK_SGK1_ST	Q9H4A3	WNK1	O00141	SGK1	S306	L299F	299	Missense	distal	-7	no	8.551	9.331	EPSD	COSMIC	9.140	Gain
AGC_SGK_SGK1_ST	Q9H4A3	WNK1	O00141	SGK1	S306	L303R	303	Missense	distal	-3	no	8.551	13.899	EPSD	COSMIC	9.140	Gain
AGC_SGK_SGK1_ST	Q9H4A3	WNK1	O00141	SGK1	S378	L374R	374	Missense	distal	-4	no	9.362	9.777	EPSD	COSMIC	9.140	Up-regulation
AGC_SGK_SGK1_ST	Q9H4A3	WNK1	O00141	SGK1	S378	A372P	372	Missense	distal	-6	no	9.362	9.142	EPSD	COSMIC	9.140	Down-regulation
AGC_SGK_SGK1_ST	Q9H4A3	WNK1	O00141	SGK1	S378	S378P	378	Missense	central	0	yes	9.362	0.000	EPSD	COSMIC	9.140	Loss
AGC_SGK_SGK1_ST	Q9H4A3	WNK1	O00141	SGK1	T436	S437R	437	Missense	proximal	1	no	9.224	9.238	EPSD	COSMIC	9.140	Up-regulation
AGC_SGK_SGK1_ST	Q9H4A3	WNK1	O00141	SGK1	T436	S443T	443	Missense	distal	7	no	9.224	9.318	EPSD	COSMIC	9.140	Up-regulation
AGC_SGK_SGK1_ST	Q9H4A3	WNK1	O00141	SGK1	T436	V439A	439	Missense	distal	3	no	9.224	9.794	EPSD	COSMIC	9.140	Up-regulation
AGC_SGK_SGK1_ST	Q9H4A3	WNK1	O00141	SGK1	T436	A429V	429	Missense	distal	-7	no	9.224	10.194	EPSD	COSMIC	9.140	Up-regulation
AGC_SGK_SGK1_ST	Q9H4A3	WNK1	O00141	SGK1	S437	S437R	437	Missense	central	0	yes	14.220	0.000	EPSD	COSMIC	9.140	Loss
AGC_SGK_SGK1_ST	Q9H4A3	WNK1	O00141	SGK1	S437	S443T	443	Missense	distal	6	no	14.220	14.156	EPSD	COSMIC	9.140	Down-regulation
AGC_SGK_SGK1_ST	Q9H4A3	WNK1	O00141	SGK1	S437	V439A	439	Missense	proximal	2	no	14.220	13.878	EPSD	COSMIC	9.140	Down-regulation
AGC_SGK_SGK1_ST	Q9H4A3	WNK1	O00141	SGK1	S1105	R1100Q	1100	Missense	distal	-5	no	16.009	7.858	EPSD	COSMIC	9.140	Loss
AGC_SGK_SGK1_ST	Q9H4A3	WNK1	O00141	SGK1	S1105	S1110C	1110	Missense	distal	5	no	16.009	15.979	EPSD	COSMIC	9.140	Down-regulation
AGC_SGK_SGK1_ST	Q9H4A3	WNK1	O00141	SGK1	S1105	H1112Y	1112	Missense	distal	7	no	16.009	16.269	EPSD	COSMIC;GDSC;CCLE	9.140	Up-regulation
AGC_SGK_SGK1_ST	Q9H4A3	WNK1	O00141	SGK1	S1105	R1107K	1107	Missense	proximal	2	no	16.009	15.564	EPSD	COSMIC	9.140	Down-regulation
AGC_SGK_SGK1_ST	Q9H4A3	WNK1	O00141	SGK1	S1105	T1098I	1098	Missense	distal	-7	no	16.009	16.702	EPSD	COSMIC	9.140	Up-regulation
AGC_SGK_SGK1_ST	Q9H4A3	WNK1	O00141	SGK1	S1108	S1110C	1110	Missense	proximal	2	no	10.429	10.484	EPSD	COSMIC	9.140	Up-regulation
AGC_SGK_SGK1_ST	Q9H4A3	WNK1	O00141	SGK1	S1108	H1112Y	1112	Missense	distal	4	no	10.429	10.334	EPSD	COSMIC;GDSC;CCLE	9.140	Down-regulation
AGC_SGK_SGK1_ST	Q9H4A3	WNK1	O00141	SGK1	S1108	R1107K	1107	Missense	proximal	-1	no	10.429	10.435	EPSD	COSMIC	9.140	Up-regulation
AGC_SGK_SGK1_ST	Q9H4A3	WNK1	O00141	SGK1	S1110	S1110C	1110	Missense	central	0	yes	10.760	0.000	EPSD	COSMIC	9.140	Loss
AGC_SGK_SGK1_ST	Q9H4A3	WNK1	O00141	SGK1	S1110	H1112Y	1112	Missense	proximal	2	no	10.760	10.956	EPSD	COSMIC;GDSC;CCLE	9.140	Up-regulation
AGC_SGK_SGK1_ST	Q9H4A3	WNK1	O00141	SGK1	S1110	R1107K	1107	Missense	distal	-3	no	10.760	4.674	EPSD	COSMIC	9.140	Loss
AGC_SGK_SGK1_ST	Q9H4A3	WNK1	O00141	SGK1	S1116	S1110C	1110	Missense	distal	-6	no	9.497	9.389	EPSD	COSMIC	9.140	Down-regulation
AGC_SGK_SGK1_ST	Q9H4A3	WNK1	O00141	SGK1	S1116	H1112Y	1112	Missense	distal	-4	no	9.497	9.423	EPSD	COSMIC;GDSC;CCLE	9.140	Down-regulation
AGC_SGK_SGK1_ST	Q9H4A3	WNK1	O00141	SGK1	S1116	R1121S	1121	Missense	distal	5	no	9.497	9.510	EPSD	COSMIC	9.140	Up-regulation
AGC_SGK_SGK1_ST	Q9H4A3	WNK1	O00141	SGK1	S1246	P1243L	1243	Missense	distal	-3	no	6.588	13.337	EPSD	COSMIC	9.140	Gain
AGC_SGK_SGK1_ST	Q9H4A3	WNK1	O00141	SGK1	S1289	A1287S	1287	Missense	proximal	-2	no	12.903	12.873	EPSD	COSMIC	9.140	Down-regulation
AGC_SGK_SGK1_ST	Q9H4A3	WNK1	O00141	SGK1	S1289	A1284E	1284	Missense	distal	-5	no	12.903	8.886	EPSD	COSMIC	9.140	Loss
AGC_SGK_SGK1_ST	Q9H4A3	WNK1	O00141	SGK1	S1289	A1283D	1283	Missense	distal	-6	no	12.903	12.793	EPSD	COSMIC	9.140	Down-regulation
AGC_SGK_SGK1_ST	Q9H4A3	WNK1	O00141	SGK1	S1289	H1296Y	1296	Missense	distal	7	no	12.903	13.164	EPSD	COSMIC;CCLE	9.140	Up-regulation
AGC_SGK_SGK1_ST	Q9H4A3	WNK1	O00141	SGK1	S1289	A1284T	1284	Missense	distal	-5	no	12.903	12.788	EPSD	COSMIC	9.140	Down-regulation
AGC_SGK_SGK1_ST	Q9H4A3	WNK1	O00141	SGK1	S1299	H1296Y	1296	Missense	distal	-3	no	5.496	9.648	EPSD	COSMIC;CCLE	9.140	Gain
AGC_SGK_SGK1_ST	Q9H4A3	WNK1	O00141	SGK1	S1308	Q1305K	1305	Missense	distal	-3	no	5.846	10.422	EPSD	COSMIC	9.140	Gain
AGC_SGK_SGK1_ST	Q9H4A3	WNK1	O00141	SGK1	S1805	Q1799E	1799	Missense	distal	-6	no	11.755	11.728	EPSD	COSMIC;GDSC;CCLE	9.140	Down-regulation
AGC_SGK_SGK1_ST	Q9H4A3	WNK1	O00141	SGK1	S1805	M1808I	1808	Missense	distal	3	no	11.755	11.583	EPSD	COSMIC	9.140	Down-regulation
AGC_SGK_SGK1_ST	Q9H4A3	WNK1	O00141	SGK1	S1805	L1804F	1804	Missense	proximal	-1	no	11.755	11.536	EPSD	COSMIC	9.140	Down-regulation
AGC_SGK_SGK1_ST	Q9H4A3	WNK1	O00141	SGK1	S1887	H1884Y	1884	Missense	distal	-3	no	7.788	11.940	EPSD	COSMIC	9.140	Gain
AGC_SGK_SGK1_ST	Q9H4A3	WNK1	O00141	SGK1	S1893	S1897N	1897	Missense	distal	4	no	11.262	11.265	EPSD	COSMIC	9.140	Up-regulation
AGC_SGK_SGK1_ST	Q9H4A3	WNK1	O00141	SGK1	S1893	S1887C	1887	Missense	distal	-6	no	11.262	11.155	EPSD	COSMIC	9.140	Down-regulation
AGC_SGK_SGK1_ST	Q9H4A3	WNK1	O00141	SGK1	S1893	S1892F	1892	Missense	proximal	-1	no	11.262	10.953	EPSD	COSMIC	9.140	Down-regulation
AGC_SGK_SGK1_ST	Q9H4A3	WNK1	O00141	SGK1	S1893	S1898I	1898	Missense	distal	5	no	11.262	11.185	EPSD	COSMIC	9.140	Down-regulation
AGC_SGK_SGK1_ST	Q9H4A3	WNK1	O00141	SGK1	S2051	Q2048K	2048	Missense	distal	-3	no	7.128	11.704	EPSD	COSMIC;GDSC;CCLE	9.140	Gain
AGC_SGK_SGK1_ST	Q9H4A3	WNK1	O00141	SGK1	S2053	Q2048K	2048	Missense	distal	-5	no	6.783	10.391	EPSD	COSMIC;GDSC;CCLE	9.140	Gain
AGC_SGK_SGK1_ST	Q9H4A3	WNK1	O00141	SGK1	T2128	K2131N	2131	Missense	distal	3	no	16.442	16.301	EPSD	COSMIC	9.140	Down-regulation
AGC_SGK_SGK1_ST	Q9H4A3	WNK1	O00141	SGK1	T2128	S2135C	2135	Missense	distal	7	no	16.442	16.623	EPSD	COSMIC	9.140	Up-regulation
AGC_SGK_SGK1_ST	Q9H4A3	WNK1	O00141	SGK1	T2128	K2134R	2134	Missense	distal	6	no	16.442	16.297	EPSD	COSMIC	9.140	Down-regulation
AGC_SGK_SGK1_ST	Q9H4A3	WNK1	O00141	SGK1	S2133	K2134R	2134	Missense	proximal	1	no	9.009	9.160	EPSD	COSMIC	9.140	Gain
AGC_SGK_SGK1_ST	Q9H4A3	WNK1	O00141	SGK1	S2139	P2146H	2146	Missense	distal	7	no	9.376	9.118	EPSD	COSMIC	9.140	Loss
AGC_SGK_SGK1_ST	Q9H4A3	WNK1	O00141	SGK1	S2139	S2135C	2135	Missense	distal	-4	no	9.376	8.884	EPSD	COSMIC	9.140	Loss
AGC_SGK_SGK1_ST	Q9H4A3	WNK1	O00141	SGK1	S2139	K2134R	2134	Missense	distal	-5	no	9.376	13.919	EPSD	COSMIC	9.140	Up-regulation
AGC_SGK_SGK1_ST	Q9H4A3	WNK1	O00141	SGK1	S2139	K2144E	2144	Missense	distal	5	no	9.376	9.315	EPSD	COSMIC;GDSC;CCLE	9.140	Down-regulation
AGC_SGK_SGK1_ST	Q9H4A3	WNK1	O00141	SGK1	S2140	P2146H	2146	Missense	distal	6	no	13.307	13.418	EPSD	COSMIC	9.140	Up-regulation
AGC_SGK_SGK1_ST	Q9H4A3	WNK1	O00141	SGK1	S2140	S2135C	2135	Missense	distal	-5	no	13.307	12.290	EPSD	COSMIC	9.140	Down-regulation
AGC_SGK_SGK1_ST	Q9H4A3	WNK1	O00141	SGK1	S2140	K2134R	2134	Missense	distal	-6	no	13.307	13.161	EPSD	COSMIC	9.140	Down-regulation
AGC_SGK_SGK1_ST	Q9H4A3	WNK1	O00141	SGK1	S2140	K2144E	2144	Missense	distal	4	no	13.307	13.028	EPSD	COSMIC;GDSC;CCLE	9.140	Down-regulation
AGC_SGK_SGK1_ST	Q9H4A3	WNK1	O00141	SGK1	T2245	D2249N	2249	Missense	distal	4	no	11.723	11.819	EPSD	COSMIC	9.140	Up-regulation
AGC_SGK_SGK1_ST	Q9H4A3	WNK1	O00141	SGK1	T2245	D2248H	2248	Missense	distal	3	no	11.723	11.757	EPSD	COSMIC	9.140	Up-regulation
AGC_SGK_SGK1_ST	Q9H4A3	WNK1	O00141	SGK1	T2247	D2249N	2249	Missense	proximal	2	no	9.697	9.557	EPSD	COSMIC	9.140	Down-regulation
AGC_SGK_SGK1_ST	Q9H4A3	WNK1	O00141	SGK1	T2247	D2248H	2248	Missense	proximal	1	no	9.697	9.611	EPSD	COSMIC	9.140	Down-regulation
AGC_SGK_SGK1_ST	Q9H4A3	WNK1	O00141	SGK1	S2286	G2289W	2289	Missense	distal	3	no	13.022	12.710	EPSD	COSMIC	9.140	Down-regulation
AGC_SGK_SGK1_ST	Q9H4A3	WNK1	O00141	SGK1	S2286	A2287E	2287	Missense	proximal	1	no	13.022	13.098	EPSD	COSMIC	9.140	Up-regulation
AGC_SGK_SGK1_ST	Q9H4A3	WNK1	O00141	SGK1	S2312	S2309T	2309	Missense	distal	-3	no	9.660	11.219	EPSD	COSMIC;GDSC;CCLE	9.140	Up-regulation
AGC_SGK_SGK1_ST	Q9H4A3	WNK1	O00141	SGK1	S2312	S2306F	2306	Missense	distal	-6	no	9.660	9.135	EPSD	COSMIC	9.140	Loss
AGC_SGK_SGK1_ST	Q9H4A3	WNK1	O00141	SGK1	T2382	S2377T	2377	Missense	distal	-5	no	8.175	9.248	EPSD	COSMIC	9.140	Gain
AGC_SGK_SGK1_ST	Q9BUB5	MKNK1	O00141	SGK1	T37	R32Q	32	Missense	distal	-5	no	11.035	2.885	EPSD	COSMIC;GDSC	9.140	Loss
AGC_SGK_SGK1_ST	Q9BUB5	MKNK1	O00141	SGK1	S413	Q411K	411	Missense	proximal	-2	no	13.281	13.548	EPSD	COSMIC	9.140	Up-regulation
AGC_SGK_SGK1_ST	Q9BUB5	MKNK1	O00141	SGK1	S413	E419Q	419	Missense	distal	6	no	13.281	13.244	EPSD	COSMIC	9.140	Down-regulation
AGC_SGK_SGK1_ST	Q9BUB5	MKNK1	O00141	SGK1	S413	A407T	407	Missense	distal	-6	no	13.281	13.244	EPSD	COSMIC	9.140	Down-regulation
AGC_SGK_SGK1_ST	Q9BUB5	MKNK1	O00141	SGK1	S413	E419K	419	Missense	distal	6	no	13.281	13.468	EPSD	COSMIC	9.140	Up-regulation
AGC_SGK_SGK1_ST	P14672	SLC2A4	O00141	SGK1	S274	Q277L	277	Missense	distal	3	no	17.937	17.793	PhosphoSitePlus	COSMIC	9.140	Down-regulation
AGC_SGK_SGK1_ST	O43524	FOXO3	O00141	SGK1	S30	R29L	29	Missense	proximal	-1	no	9.790	9.676	EPSD	COSMIC	9.140	Down-regulation
AGC_SGK_SGK1_ST	O43524	FOXO3	O00141	SGK1	T32	R29L	29	Missense	distal	-3	no	15.657	10.308	EPSD	COSMIC	9.140	Down-regulation
AGC_SGK_SGK1_ST	O43524	FOXO3	O00141	SGK1	S75	M77L	77	Missense	proximal	2	no	10.869	10.845	EPSD	COSMIC	9.140	Down-regulation
AGC_SGK_SGK1_ST	O43524	FOXO3	O00141	SGK1	S181	P174S	174	Missense	distal	-7	no	9.936	9.032	EPSD	COSMIC	9.140	Loss
AGC_SGK_SGK1_ST	O43524	FOXO3	O00141	SGK1	S181	E185K	185	Missense	distal	4	no	9.936	10.216	EPSD	COSMIC	9.140	Up-regulation
AGC_SGK_SGK1_ST	O43524	FOXO3	O00141	SGK1	S253	S253F	253	Missense	central	0	yes	17.222	0.000	EPSD	COSMIC	9.140	Loss
AGC_SGK_SGK1_ST	O43524	FOXO3	O00141	SGK1	S253	R248W	248	Missense	distal	-5	no	17.222	9.564	EPSD	COSMIC	9.140	Down-regulation
AGC_SGK_SGK1_ST	O43524	FOXO3	O00141	SGK1	S280	Q275R	275	Missense	distal	-5	no	2.135	10.286	EPSD	COSMIC	9.140	Gain
AGC_SGK_SGK1_ST	O43524	FOXO3	O00141	SGK1	S299	P295L	295	Missense	distal	-4	no	10.526	10.817	EPSD	COSMIC	9.140	Up-regulation
AGC_SGK_SGK1_ST	O43524	FOXO3	O00141	SGK1	S315	S318C	318	Missense	distal	3	no	19.864	19.683	PhosphoSitePlus	COSMIC	9.140	Down-regulation
AGC_SGK_SGK1_ST	O43524	FOXO3	O00141	SGK1	S318	S318C	318	Missense	central	0	yes	10.089	0.000	EPSD	COSMIC	9.140	Loss
AGC_SGK_SGK1_ST	O43524	FOXO3	O00141	SGK1	S318	R323C	323	Missense	distal	5	no	10.089	10.072	EPSD	COSMIC	9.140	Down-regulation
AGC_SGK_SGK1_ST	O43524	FOXO3	O00141	SGK1	S318	R323H	323	Missense	distal	5	no	10.089	10.070	EPSD	COSMIC	9.140	Down-regulation
AGC_SGK_SGK1_ST	O43524	FOXO3	O00141	SGK1	S357	P361L	361	Missense	distal	4	no	10.122	10.198	EPSD	COSMIC;GDSC;CCLE	9.140	Up-regulation
AGC_SGK_SGK1_ST	O43524	FOXO3	O00141	SGK1	S357	T363A	363	Missense	distal	6	no	10.122	10.181	EPSD	COSMIC;GDSC;CCLE	9.140	Up-regulation
AGC_SGK_SGK1_ST	O43524	FOXO3	O00141	SGK1	S402	P397R	397	Missense	distal	-5	no	1.441	10.845	EPSD	COSMIC	9.140	Gain
AGC_SGK_SGK1_ST	O43524	FOXO3	O00141	SGK1	S413	F414Y	414	Missense	proximal	1	no	10.023	9.881	EPSD	COSMIC	9.140	Down-regulation
AGC_SGK_SGK1_ST	O43524	FOXO3	O00141	SGK1	S421	G424V	424	Missense	distal	3	no	10.400	10.066	EPSD	COSMIC	9.140	Down-regulation
AGC_SGK_SGK1_ST	O43524	FOXO3	O00141	SGK1	S421	F414Y	414	Missense	distal	-7	no	10.400	9.765	EPSD	COSMIC	9.140	Down-regulation
AGC_SGK_SGK1_ST	O43524	FOXO3	O00141	SGK1	S551	M557R	557	Missense	distal	6	no	11.866	11.996	EPSD	COSMIC	9.140	Up-regulation
AGC_SGK_SGK1_ST	O43524	FOXO3	O00141	SGK1	S553	M557R	557	Missense	distal	4	no	13.827	13.944	EPSD	COSMIC	9.140	Up-regulation
AGC_SGK_SGK1_ST	P28482	MAPK1	O00141	SGK1	S29	P23S	23	Missense	distal	-6	no	11.990	12.259	PhosphoSitePlus	COSMIC	9.140	Up-regulation
AGC_SGK_SGK1_ST	P28482	MAPK1	O00141	SGK1	S29	E33Q	33	Missense	distal	4	no	11.990	11.992	PhosphoSitePlus	COSMIC	9.140	Up-regulation
AGC_SGK_SGK1_ST	P28482	MAPK1	O00141	SGK1	S29	G34D	34	Missense	distal	5	no	11.990	12.002	PhosphoSitePlus	COSMIC	9.140	Up-regulation
AGC_SGK_SGK1_ST	P28482	MAPK1	O00141	SGK1	S29	I31M	31	Missense	proximal	2	no	11.990	11.876	PhosphoSitePlus	COSMIC	9.140	Down-regulation
AGC_SGK_SGK1_ST	P28482	MAPK1	O00141	SGK1	T190	F183S	183	Missense	distal	-7	no	9.577	8.138	EPSD	COSMIC	9.140	Loss
AGC_SGK_SGK1_ST	Q96J92	WNK4	O00141	SGK1	S47	R44H	44	Missense	distal	-3	no	18.127	8.508	EPSD	COSMIC	9.140	Loss
AGC_SGK_SGK1_ST	Q96J92	WNK4	O00141	SGK1	S331	A330T	330	Missense	proximal	-1	no	9.204	9.203	EPSD	COSMIC	9.140	Down-regulation
AGC_SGK_SGK1_ST	Q96J92	WNK4	O00141	SGK1	S575	F569V	569	Missense	distal	-6	no	14.039	14.123	EPSD	COSMIC	9.140	Up-regulation
AGC_SGK_SGK1_ST	Q96J92	WNK4	O00141	SGK1	S575	R572S	572	Missense	distal	-3	no	14.039	7.134	EPSD	COSMIC	9.140	Loss
AGC_SGK_SGK1_ST	Q96J92	WNK4	O00141	SGK1	S575	R572C	572	Missense	distal	-3	no	14.039	5.978	EPSD	COSMIC	9.140	Loss
AGC_SGK_SGK1_ST	Q96J92	WNK4	O00141	SGK1	S680	S674F	674	Missense	distal	-6	no	17.705	17.180	EPSD	COSMIC	9.140	Down-regulation
AGC_SGK_SGK1_ST	Q96J92	WNK4	O00141	SGK1	S1201	R1199S	1199	Missense	proximal	-2	no	17.787	17.690	PhosphoSitePlus;EPSD	COSMIC	9.140	Down-regulation
AGC_SGK_SGK1_ST	Q9Y2I7	PIKFYVE	O00141	SGK1	T22	H26R	26	Missense	distal	4	no	12.881	12.852	EPSD	COSMIC	9.140	Down-regulation
AGC_SGK_SGK1_ST	Q9Y2I7	PIKFYVE	O00141	SGK1	S25	H26R	26	Missense	proximal	1	no	10.456	10.471	EPSD	COSMIC	9.140	Up-regulation
AGC_SGK_SGK1_ST	Q9Y2I7	PIKFYVE	O00141	SGK1	S47	F42L	42	Missense	distal	-5	no	5.838	9.612	EPSD	COSMIC	9.140	Gain
AGC_SGK_SGK1_ST	Q9Y2I7	PIKFYVE	O00141	SGK1	T90	V86A	86	Missense	distal	-4	no	12.209	13.744	EPSD	COSMIC	9.140	Up-regulation
AGC_SGK_SGK1_ST	Q9Y2I7	PIKFYVE	O00141	SGK1	S105	R110G	110	Missense	distal	5	no	12.382	12.342	EPSD	COSMIC	9.140	Down-regulation
AGC_SGK_SGK1_ST	Q9Y2I7	PIKFYVE	O00141	SGK1	S105	R111Q	111	Missense	distal	6	no	12.382	12.303	EPSD	COSMIC	9.140	Down-regulation
AGC_SGK_SGK1_ST	Q9Y2I7	PIKFYVE	O00141	SGK1	S223	S219L	219	Missense	distal	-4	no	12.585	11.865	EPSD	COSMIC	9.140	Down-regulation
AGC_SGK_SGK1_ST	Q9Y2I7	PIKFYVE	O00141	SGK1	S291	G297E	297	Missense	distal	6	no	10.858	11.001	EPSD	COSMIC	9.140	Up-regulation
AGC_SGK_SGK1_ST	Q9Y2I7	PIKFYVE	O00141	SGK1	S316	P319S	319	Missense	distal	3	no	9.785	10.181	EPSD	COSMIC	9.140	Up-regulation
AGC_SGK_SGK1_ST	Q9Y2I7	PIKFYVE	O00141	SGK1	S318	P319S	319	Missense	proximal	1	no	15.541	15.428	PhosphoSitePlus	COSMIC	9.140	Down-regulation
AGC_SGK_SGK1_ST	Q9Y2I7	PIKFYVE	O00141	SGK1	S329	R334G	334	Missense	distal	5	no	11.434	11.395	EPSD	COSMIC	9.140	Down-regulation
AGC_SGK_SGK1_ST	Q9Y2I7	PIKFYVE	O00141	SGK1	S329	S327F	327	Missense	proximal	-2	no	11.434	10.592	EPSD	COSMIC	9.140	Down-regulation
AGC_SGK_SGK1_ST	Q9Y2I7	PIKFYVE	O00141	SGK1	T341	R334G	334	Missense	distal	-7	no	10.930	11.816	EPSD	COSMIC	9.140	Up-regulation
AGC_SGK_SGK1_ST	Q9Y2I7	PIKFYVE	O00141	SGK1	T380	V386A	386	Missense	distal	6	no	8.987	9.280	EPSD	COSMIC	9.140	Gain
AGC_SGK_SGK1_ST	Q9Y2I7	PIKFYVE	O00141	SGK1	S499	P494L	494	Missense	distal	-5	no	6.172	11.349	EPSD	COSMIC	9.140	Gain
AGC_SGK_SGK1_ST	Q9Y2I7	PIKFYVE	O00141	SGK1	S501	P494L	494	Missense	distal	-7	no	11.308	11.062	EPSD	COSMIC	9.140	Down-regulation
AGC_SGK_SGK1_ST	Q9Y2I7	PIKFYVE	O00141	SGK1	S845	T838I	838	Missense	distal	-7	no	12.828	13.521	EPSD	COSMIC;CCLE	9.140	Up-regulation
AGC_SGK_SGK1_ST	Q9Y2I7	PIKFYVE	O00141	SGK1	S845	T838A	838	Missense	distal	-7	no	12.828	12.790	EPSD	COSMIC	9.140	Down-regulation
AGC_SGK_SGK1_ST	Q9Y2I7	PIKFYVE	O00141	SGK1	S1474	S1475F	1475	Missense	proximal	1	no	8.914	9.149	EPSD	COSMIC	9.140	Gain
AGC_SGK_SGK1_ST	Q9Y2I7	PIKFYVE	O00141	SGK1	S1708	P1701T	1701	Missense	distal	-7	no	9.197	8.506	EPSD	COSMIC	9.140	Loss
AGC_SGK_SGK1_ST	Q9Y2I7	PIKFYVE	O00141	SGK1	S1708	P1701L	1701	Missense	distal	-7	no	9.197	8.951	EPSD	COSMIC	9.140	Loss
AGC_SGK_SGK1_ST	Q9Y2I7	PIKFYVE	O00141	SGK1	S1745	G1742A	1742	Missense	distal	-3	no	9.449	10.719	EPSD	COSMIC	9.140	Up-regulation
AGC_SGK_SGK1_ST	Q9Y2I7	PIKFYVE	O00141	SGK1	S1745	R1748K	1748	Missense	distal	3	no	9.449	9.581	EPSD	COSMIC	9.140	Up-regulation
AGC_SGK_SGK1_ST	Q6R327	RICTOR	O00141	SGK1	S21	E23D	23	Missense	proximal	2	no	19.124	19.140	EPSD	COSMIC;GDSC;CCLE	9.140	Up-regulation
AGC_SGK_SGK1_ST	Q6R327	RICTOR	O00141	SGK1	S21	P27S	27	Missense	distal	6	no	19.124	19.325	EPSD	COSMIC	9.140	Up-regulation
AGC_SGK_SGK1_ST	Q6R327	RICTOR	O00141	SGK1	S21	R14Q	14	Missense	distal	-7	no	19.124	19.653	EPSD	COSMIC	9.140	Up-regulation
AGC_SGK_SGK1_ST	Q6R327	RICTOR	O00141	SGK1	S21	G17E	17	Missense	distal	-4	no	19.124	19.148	EPSD	COSMIC	9.140	Up-regulation
AGC_SGK_SGK1_ST	Q6R327	RICTOR	O00141	SGK1	S35	E40D	40	Missense	distal	5	no	13.983	13.984	EPSD	COSMIC	9.140	Up-regulation
AGC_SGK_SGK1_ST	Q6R327	RICTOR	O00141	SGK1	S35	D29E	29	Missense	distal	-6	no	13.983	13.952	EPSD	COSMIC	9.140	Down-regulation
AGC_SGK_SGK1_ST	Q6R327	RICTOR	O00141	SGK1	T268	L273V	273	Missense	distal	5	no	10.284	10.236	EPSD	COSMIC	9.140	Down-regulation
AGC_SGK_SGK1_ST	Q6R327	RICTOR	O00141	SGK1	T268	H261N	261	Missense	distal	-7	no	10.284	10.089	EPSD	COSMIC	9.140	Down-regulation
AGC_SGK_SGK1_ST	Q6R327	RICTOR	O00141	SGK1	S383	P378L	378	Missense	distal	-5	no	11.689	16.866	EPSD	COSMIC	9.140	Up-regulation
AGC_SGK_SGK1_ST	Q6R327	RICTOR	O00141	SGK1	S383	R384G	384	Missense	proximal	1	no	11.689	11.866	EPSD	COSMIC	9.140	Up-regulation
AGC_SGK_SGK1_ST	Q6R327	RICTOR	O00141	SGK1	S383	R380L	380	Missense	distal	-3	no	11.689	6.340	EPSD	COSMIC	9.140	Loss
AGC_SGK_SGK1_ST	Q6R327	RICTOR	O00141	SGK1	S383	L377I	377	Missense	distal	-6	no	11.689	11.509	EPSD	COSMIC	9.140	Down-regulation
AGC_SGK_SGK1_ST	Q6R327	RICTOR	O00141	SGK1	S383	H379Y	379	Missense	distal	-4	no	11.689	11.615	EPSD	COSMIC	9.140	Down-regulation
AGC_SGK_SGK1_ST	Q6R327	RICTOR	O00141	SGK1	S703	L698V	698	Missense	distal	-5	no	11.742	6.851	EPSD	COSMIC	9.140	Loss
AGC_SGK_SGK1_ST	Q6R327	RICTOR	O00141	SGK1	S703	S703F	703	Missense	central	0	yes	11.742	0.000	EPSD	COSMIC	9.140	Loss
AGC_SGK_SGK1_ST	Q6R327	RICTOR	O00141	SGK1	S703	S704G	704	Missense	proximal	1	no	11.742	11.933	EPSD	COSMIC	9.140	Up-regulation
AGC_SGK_SGK1_ST	Q6R327	RICTOR	O00141	SGK1	S810	S816F	816	Missense	distal	6	no	12.466	12.016	EPSD	COSMIC	9.140	Down-regulation
AGC_SGK_SGK1_ST	Q6R327	RICTOR	O00141	SGK1	S810	L804V	804	Missense	distal	-6	no	12.466	12.211	EPSD	COSMIC	9.140	Down-regulation
AGC_SGK_SGK1_ST	Q6R327	RICTOR	O00141	SGK1	S1035	P1041S	1041	Missense	distal	6	no	12.473	12.674	EPSD	COSMIC;GDSC;CCLE	9.140	Up-regulation
AGC_SGK_SGK1_ST	Q6R327	RICTOR	O00141	SGK1	S1035	T1029A	1029	Missense	distal	-6	no	12.473	12.509	EPSD	COSMIC	9.140	Up-regulation
AGC_SGK_SGK1_ST	Q6R327	RICTOR	O00141	SGK1	S1121	P1115A	1115	Missense	distal	-6	no	9.482	9.702	EPSD	COSMIC	9.140	Up-regulation
AGC_SGK_SGK1_ST	Q6R327	RICTOR	O00141	SGK1	T1133	D1140E	1140	Missense	distal	7	no	11.807	11.850	EPSD	COSMIC	9.140	Up-regulation
AGC_SGK_SGK1_ST	Q6R327	RICTOR	O00141	SGK1	T1133	T1135A	1135	Missense	proximal	2	no	11.807	11.672	EPSD	COSMIC	9.140	Down-regulation
AGC_SGK_SGK1_ST	Q6R327	RICTOR	O00141	SGK1	T1133	D1140Y	1140	Missense	distal	7	no	11.807	11.935	EPSD	COSMIC	9.140	Up-regulation
AGC_SGK_SGK1_ST	Q6R327	RICTOR	O00141	SGK1	T1135	D1140E	1140	Missense	distal	5	no	19.326	19.325	PhosphoSitePlus	COSMIC	9.140	Down-regulation
AGC_SGK_SGK1_ST	Q6R327	RICTOR	O00141	SGK1	T1135	T1135A	1135	Missense	central	0	yes	19.326	0.000	PhosphoSitePlus	COSMIC	9.140	Loss
AGC_SGK_SGK1_ST	Q6R327	RICTOR	O00141	SGK1	T1135	D1140Y	1140	Missense	distal	5	no	19.326	19.320	PhosphoSitePlus	COSMIC	9.140	Down-regulation
AGC_SGK_SGK1_ST	Q6R327	RICTOR	O00141	SGK1	S1138	D1140E	1140	Missense	proximal	2	no	12.757	12.740	EPSD	COSMIC	9.140	Down-regulation
AGC_SGK_SGK1_ST	Q6R327	RICTOR	O00141	SGK1	S1138	T1135A	1135	Missense	distal	-3	no	12.757	12.818	EPSD	COSMIC	9.140	Up-regulation
AGC_SGK_SGK1_ST	Q6R327	RICTOR	O00141	SGK1	S1138	D1140Y	1140	Missense	proximal	2	no	12.757	12.917	EPSD	COSMIC	9.140	Up-regulation
AGC_SGK_SGK1_ST	Q6R327	RICTOR	O00141	SGK1	S1177	E1180D	1180	Missense	distal	3	no	9.303	9.391	EPSD	COSMIC	9.140	Up-regulation
AGC_SGK_SGK1_ST	Q6R327	RICTOR	O00141	SGK1	S1177	E1170Q	1170	Missense	distal	-7	no	9.303	9.099	EPSD	COSMIC	9.140	Loss
AGC_SGK_SGK1_ST	Q6R327	RICTOR	O00141	SGK1	S1177	D1171Y	1171	Missense	distal	-6	no	9.303	9.280	EPSD	COSMIC	9.140	Down-regulation
AGC_SGK_SGK1_ST	Q6R327	RICTOR	O00141	SGK1	S1177	E1180A	1180	Missense	distal	3	no	9.303	9.556	EPSD	COSMIC	9.140	Up-regulation
AGC_SGK_SGK1_ST	Q6R327	RICTOR	O00141	SGK1	S1177	E1180K	1180	Missense	distal	3	no	9.303	9.623	EPSD	COSMIC	9.140	Up-regulation
AGC_SGK_SGK1_ST	Q6R327	RICTOR	O00141	SGK1	S1177	I1178T	1178	Missense	proximal	1	no	9.303	9.226	EPSD	COSMIC	9.140	Down-regulation
AGC_SGK_SGK1_ST	Q6R327	RICTOR	O00141	SGK1	S1177	K1184T	1184	Missense	distal	7	no	9.303	9.504	EPSD	COSMIC;GDSC;CCLE	9.140	Up-regulation
AGC_SGK_SGK1_ST	Q6R327	RICTOR	O00141	SGK1	S1177	T1172A	1172	Missense	distal	-5	no	9.303	9.418	EPSD	COSMIC	9.140	Up-regulation
AGC_SGK_SGK1_ST	Q6R327	RICTOR	O00141	SGK1	S1219	K1214Q	1214	Missense	distal	-5	no	14.980	11.372	EPSD	COSMIC	9.140	Down-regulation
AGC_SGK_SGK1_ST	Q6R327	RICTOR	O00141	SGK1	S1219	M1213L	1213	Missense	distal	-6	no	14.980	14.997	EPSD	COSMIC	9.140	Up-regulation
AGC_SGK_SGK1_ST	Q6R327	RICTOR	O00141	SGK1	S1219	Q1218P	1218	Missense	proximal	-1	no	14.980	14.922	EPSD	COSMIC	9.140	Down-regulation
AGC_SGK_SGK1_ST	Q6R327	RICTOR	O00141	SGK1	S1302	P1297S	1297	Missense	distal	-5	no	6.507	10.666	EPSD	COSMIC	9.140	Gain
AGC_SGK_SGK1_ST	Q6R327	RICTOR	O00141	SGK1	S1353	P1354L	1354	Missense	proximal	1	no	9.383	9.329	EPSD	COSMIC	9.140	Down-regulation
AGC_SGK_SGK1_ST	Q6R327	RICTOR	O00141	SGK1	S1353	F1360C	1360	Missense	distal	7	no	9.383	8.879	EPSD	COSMIC	9.140	Loss
AGC_SGK_SGK1_ST	Q6R327	RICTOR	O00141	SGK1	S1378	R1379K	1379	Missense	proximal	1	no	10.137	9.986	EPSD	COSMIC	9.140	Down-regulation
AGC_SGK_SGK1_ST	Q6R327	RICTOR	O00141	SGK1	S1378	E1372K	1372	Missense	distal	-6	no	10.137	10.431	EPSD	COSMIC	9.140	Up-regulation
AGC_SGK_SGK1_ST	Q6R327	RICTOR	O00141	SGK1	S1378	R1379S	1379	Missense	proximal	1	no	10.137	10.123	EPSD	COSMIC	9.140	Down-regulation
AGC_SGK_SGK1_ST	Q6R327	RICTOR	O00141	SGK1	S1378	L1384S	1384	Missense	distal	6	no	10.137	10.251	EPSD	COSMIC;GDSC;CCLE	9.140	Up-regulation
AGC_SGK_SGK1_ST	Q6R327	RICTOR	O00141	SGK1	S1378	F1380L	1380	Missense	proximal	2	no	10.137	9.810	EPSD	COSMIC	9.140	Down-regulation
AGC_SGK_SGK1_ST	Q6R327	RICTOR	O00141	SGK1	S1385	F1380L	1380	Missense	distal	-5	no	5.476	9.250	EPSD	COSMIC	9.140	Gain
AGC_SGK_SGK1_ST	Q6R327	RICTOR	O00141	SGK1	S1408	R1410W	1410	Missense	proximal	2	no	10.658	10.801	EPSD	COSMIC	9.140	Up-regulation
AGC_SGK_SGK1_ST	Q6R327	RICTOR	O00141	SGK1	S1408	S1406F	1406	Missense	proximal	-2	no	10.658	9.816	EPSD	COSMIC	9.140	Down-regulation
AGC_SGK_SGK1_ST	Q6R327	RICTOR	O00141	SGK1	S1408	T1402P	1402	Missense	distal	-6	no	10.658	10.474	EPSD	COSMIC	9.140	Down-regulation
AGC_SGK_SGK1_ST	Q6R327	RICTOR	O00141	SGK1	S1408	R1410Q	1410	Missense	proximal	2	no	10.658	10.438	EPSD	COSMIC	9.140	Down-regulation
AGC_SGK_SGK1_ST	P45985	MAP2K4	O00141	SGK1	S7	P4L	4	Missense	distal	-3	no	3.466	10.216	EPSD	COSMIC	9.140	Gain
AGC_SGK_SGK1_ST	P45985	MAP2K4	O00141	SGK1	S80	E74K	74	Missense	distal	-6	no	20.300	20.594	PhosphoSitePlus	COSMIC	9.140	Up-regulation
AGC_SGK_SGK1_ST	P45985	MAP2K4	O00141	SGK1	S80	R77G	77	Missense	distal	-3	no	20.300	13.744	PhosphoSitePlus	COSMIC	9.140	Down-regulation
AGC_SGK_SGK1_ST	P45985	MAP2K4	O00141	SGK1	S80	G85R	85	Missense	distal	5	no	20.300	20.339	PhosphoSitePlus	COSMIC	9.140	Up-regulation
AGC_SGK_SGK1_ST	P45985	MAP2K4	O00141	SGK1	S90	G85R	85	Missense	distal	-5	no	7.962	13.323	EPSD	COSMIC	9.140	Gain
AGC_SGK_SGK1_ST	P45985	MAP2K4	O00141	SGK1	S257	G252R	252	Missense	distal	-5	no	8.758	14.119	EPSD	COSMIC	9.140	Gain
AGC_SGK_SGK1_ST	P45985	MAP2K4	O00141	SGK1	S257	L254R	254	Missense	distal	-3	no	8.758	14.107	EPSD	COSMIC;GDSC;CCLE	9.140	Gain
AGC_SGK_SGK1_ST	P45985	MAP2K4	O00141	SGK1	S292	G294R	294	Missense	proximal	2	no	10.208	10.181	EPSD	COSMIC	9.140	Down-regulation
AGC_SGK_SGK1_ST	P45985	MAP2K4	O00141	SGK1	S292	S292N	292	Missense	central	0	yes	10.208	0.000	EPSD	COSMIC	9.140	Loss
AGC_SGK_SGK1_ST	P45985	MAP2K4	O00141	SGK1	S292	D289G	289	Missense	distal	-3	no	10.208	12.832	EPSD	COSMIC	9.140	Up-regulation
AGC_SGK_SGK1_ST	P45985	MAP2K4	O00141	SGK1	S292	S288F	288	Missense	distal	-4	no	10.208	8.033	EPSD	COSMIC	9.140	Loss
AGC_SGK_SGK1_ST	P45985	MAP2K4	O00141	SGK1	S292	D289Y	289	Missense	distal	-3	no	10.208	13.921	EPSD	COSMIC	9.140	Up-regulation
AGC_SGK_SGK1_ST	P45985	MAP2K4	O00141	SGK1	S292	E299D	299	Missense	distal	7	no	10.208	10.165	EPSD	COSMIC	9.140	Down-regulation
AGC_SGK_SGK1_ST	P45985	MAP2K4	O00141	SGK1	S292	V290F	290	Missense	proximal	-2	no	10.208	10.154	EPSD	COSMIC	9.140	Down-regulation
AGC_SGK_SGK1_ST	P45985	MAP2K4	O00141	SGK1	S292	S292R	292	Missense	central	0	yes	10.208	0.000	EPSD	COSMIC	9.140	Loss
AGC_SGK_SGK1_ST	P45985	MAP2K4	O00141	SGK1	S292	I295F	295	Missense	distal	3	no	10.208	9.889	EPSD	COSMIC	9.140	Down-regulation
AGC_SGK_SGK1_ST	P45985	MAP2K4	O00141	SGK1	S292	S288P	288	Missense	distal	-4	no	10.208	9.197	EPSD	COSMIC	9.140	Down-regulation
AGC_SGK_SGK1_ST	P45985	MAP2K4	O00141	SGK1	S292	S288C	288	Missense	distal	-4	no	10.208	9.716	EPSD	COSMIC	9.140	Down-regulation
AGC_SGK_SGK1_ST	P45985	MAP2K4	O00141	SGK1	S292	G294V	294	Missense	proximal	2	no	10.208	10.282	EPSD	COSMIC	9.140	Up-regulation
AGC_SGK_SGK1_ST	P45985	MAP2K4	O00141	SGK1	S292	D289V	289	Missense	distal	-3	no	10.208	7.669	EPSD	COSMIC	9.140	Loss
AGC_SGK_SGK1_ST	P45985	MAP2K4	O00141	SGK1	S292	D289N	289	Missense	distal	-3	no	10.208	10.305	EPSD	COSMIC	9.140	Up-regulation
AGC_SGK_SGK1_ST	P45985	MAP2K4	O00141	SGK1	S292	E299V	299	Missense	distal	7	no	10.208	10.395	EPSD	COSMIC	9.140	Up-regulation
AGC_SGK_SGK1_ST	P45985	MAP2K4	O00141	SGK1	S292	D285N	285	Missense	distal	-7	no	10.208	9.714	EPSD	COSMIC	9.140	Down-regulation
AGC_SGK_SGK1_ST	P45985	MAP2K4	O00141	SGK1	S292	W291R	291	Missense	proximal	-1	no	10.208	10.451	EPSD	COSMIC	9.140	Up-regulation
AGC_SGK_SGK1_ST	P45985	MAP2K4	O00141	SGK1	S292	I295M	295	Missense	distal	3	no	10.208	10.380	EPSD	COSMIC	9.140	Up-regulation
AGC_SGK_SGK1_ST	P45985	MAP2K4	O00141	SGK1	S292	L297F	297	Missense	distal	5	no	10.208	10.126	EPSD	COSMIC	9.140	Down-regulation
AGC_SGK_SGK1_ST	P45985	MAP2K4	O00141	SGK1	S292	T296R	296	Missense	distal	4	no	10.208	10.200	EPSD	COSMIC	9.140	Down-regulation
AGC_SGK_SGK1_ST	P45985	MAP2K4	O00141	SGK1	T296	W291R	291	Missense	distal	-5	no	3.768	11.425	EPSD	COSMIC	9.140	Gain
AGC_SGK_SGK1_ST	O14920	IKBKB	O00141	SGK1	S239	R236W	236	Missense	distal	-3	no	9.764	0.069	EPSD	COSMIC	9.140	Loss
AGC_SGK_SGK1_ST	O14920	IKBKB	O00141	SGK1	S239	V241E	241	Missense	proximal	2	no	9.764	9.452	EPSD	COSMIC	9.140	Down-regulation
AGC_SGK_SGK1_ST	O14920	IKBKB	O00141	SGK1	S476	N470K	470	Missense	distal	-6	no	9.016	9.147	EPSD	COSMIC	9.140	Gain
AGC_SGK_SGK1_ST	P42858	HTT	O00141	SGK1	S417	R416H	416	Missense	proximal	-1	no	10.943	10.830	EPSD	COSMIC	9.140	Down-regulation
AGC_SGK_SGK1_ST	P42858	HTT	O00141	SGK1	S419	R416H	416	Missense	distal	-3	no	21.602	11.983	PhosphoSitePlus	COSMIC	9.140	Down-regulation
AGC_SGK_SGK1_ST	P42858	HTT	O00141	SGK1	S463	V461A	461	Missense	proximal	-2	no	9.042	9.860	EPSD	COSMIC	9.140	Gain
AGC_SGK_SGK1_ST	P42858	HTT	O00141	SGK1	S464	V461A	461	Missense	distal	-3	no	4.171	10.603	EPSD	COSMIC	9.140	Gain
AGC_SGK_SGK1_ST	P42858	HTT	O00141	SGK1	S621	E615K	615	Missense	distal	-6	no	9.218	9.512	EPSD	COSMIC	9.140	Up-regulation
AGC_SGK_SGK1_ST	P42858	HTT	O00141	SGK1	S640	M633T	633	Missense	distal	-7	no	13.413	12.948	EPSD	COSMIC	9.140	Down-regulation
AGC_SGK_SGK1_ST	P42858	HTT	O00141	SGK1	S1111	L1105P	1105	Missense	distal	-6	no	12.659	12.577	EPSD	COSMIC	9.140	Down-regulation
AGC_SGK_SGK1_ST	P42858	HTT	O00141	SGK1	S1111	P1117S	1117	Missense	distal	6	no	12.659	12.860	EPSD	COSMIC	9.140	Up-regulation
AGC_SGK_SGK1_ST	P42858	HTT	O00141	SGK1	S1111	A1115G	1115	Missense	distal	4	no	12.659	12.423	EPSD	COSMIC	9.140	Down-regulation
AGC_SGK_SGK1_ST	P42858	HTT	O00141	SGK1	S1171	L1178P	1178	Missense	distal	7	no	10.038	10.090	EPSD	COSMIC	9.140	Up-regulation
AGC_SGK_SGK1_ST	P42858	HTT	O00141	SGK1	S1171	T1173A	1173	Missense	proximal	2	no	10.038	9.903	EPSD	COSMIC	9.140	Down-regulation
AGC_SGK_SGK1_ST	P42858	HTT	O00141	SGK1	S1216	T1215I	1215	Missense	proximal	-1	no	9.201	9.060	EPSD	COSMIC	9.140	Loss
AGC_SGK_SGK1_ST	P42858	HTT	O00141	SGK1	S1216	G1217V	1217	Missense	proximal	1	no	9.201	9.136	EPSD	COSMIC	9.140	Loss
AGC_SGK_SGK1_ST	P42858	HTT	O00141	SGK1	S1349	Y1355H	1355	Missense	distal	6	no	13.169	13.214	EPSD	COSMIC	9.140	Up-regulation
AGC_SGK_SGK1_ST	P42858	HTT	O00141	SGK1	S1865	S1862N	1862	Missense	distal	-3	no	10.133	7.956	EPSD	COSMIC	9.140	Loss
AGC_SGK_SGK1_ST	P42858	HTT	O00141	SGK1	T2455	G2457S	2457	Missense	proximal	2	no	12.258	11.932	EPSD	COSMIC	9.140	Down-regulation
AGC_SGK_SGK1_ST	P42858	HTT	O00141	SGK1	T2455	I2450V	2450	Missense	distal	-5	no	12.258	9.781	EPSD	COSMIC	9.140	Down-regulation
AGC_SGK_SGK1_ST	P42858	HTT	O00141	SGK1	T2455	S2460N	2460	Missense	distal	5	no	12.258	12.240	EPSD	COSMIC	9.140	Down-regulation
AGC_SGK_SGK1_ST	P42858	HTT	O00141	SGK1	T2570	A2569V	2569	Missense	proximal	-1	no	10.575	10.389	EPSD	COSMIC	9.140	Down-regulation
AGC_SGK_SGK1_ST	P42858	HTT	O00141	SGK1	T2570	Y2574C	2574	Missense	distal	4	no	10.575	10.675	EPSD	COSMIC	9.140	Up-regulation
AGC_SGK_SGK1_ST	P42858	HTT	O00141	SGK1	S2812	N2813K	2813	Missense	proximal	1	no	9.523	9.432	EPSD	COSMIC	9.140	Down-regulation
AGC_SGK_SGK1_ST	P42858	HTT	O00141	SGK1	S2812	Y2809C	2809	Missense	distal	-3	no	9.523	6.928	EPSD	COSMIC	9.140	Loss
AGC_SGK_SGK1_ST	P42858	HTT	O00141	SGK1	S2948	P2943L	2943	Missense	distal	-5	no	4.212	9.389	EPSD	COSMIC	9.140	Gain
AGC_SGK_SGK1_ST	Q969H0	FBXW7	O00141	SGK1	S18	K11R	11	Missense	distal	-7	no	11.099	11.429	EPSD	COSMIC	9.140	Up-regulation
AGC_SGK_SGK1_ST	Q969H0	FBXW7	O00141	SGK1	S18	R13L	13	Missense	distal	-5	no	11.099	6.871	EPSD	COSMIC	9.140	Loss
AGC_SGK_SGK1_ST	Q969H0	FBXW7	O00141	SGK1	S227	R223L	223	Missense	distal	-4	no	18.838	18.423	PhosphoSitePlus	COSMIC	9.140	Down-regulation
AGC_SGK_SGK1_ST	Q969H0	FBXW7	O00141	SGK1	S227	P230L	230	Missense	distal	3	no	18.838	18.847	PhosphoSitePlus	COSMIC	9.140	Up-regulation
AGC_SGK_SGK1_ST	Q969H0	FBXW7	O00141	SGK1	S227	R223C	223	Missense	distal	-4	no	18.838	18.651	PhosphoSitePlus	COSMIC	9.140	Down-regulation
AGC_SGK_SGK1_ST	Q969H0	FBXW7	O00141	SGK1	S227	R222Q	222	Missense	distal	-5	no	18.838	10.687	PhosphoSitePlus	COSMIC	9.140	Down-regulation
AGC_SGK_SGK1_ST	Q969H0	FBXW7	O00141	SGK1	S227	L234M	234	Missense	distal	7	no	18.838	18.792	PhosphoSitePlus	COSMIC	9.140	Down-regulation
AGC_SGK_SGK1_ST	Q969H0	FBXW7	O00141	SGK1	T692	A685E	685	Missense	distal	-7	no	13.642	14.177	EPSD	COSMIC	9.140	Up-regulation
AGC_SGK_SGK1_ST	Q969H0	FBXW7	O00141	SGK1	T692	A685V	685	Missense	distal	-7	no	13.642	14.612	EPSD	COSMIC	9.140	Up-regulation
AGC_SGK_SGK1_ST	Q969H0	FBXW7	O00141	SGK1	T692	G687V	687	Missense	distal	-5	no	13.642	9.884	EPSD	COSMIC	9.140	Down-regulation
AGC_SGK_SGK1_ST	Q969H0	FBXW7	O00141	SGK1	T692	S688I	688	Missense	distal	-4	no	13.642	12.307	EPSD	COSMIC	9.140	Down-regulation
AGC_SGK_SGK1_ST	Q969H0	FBXW7	O00141	SGK1	T692	V686D	686	Missense	distal	-6	no	13.642	13.925	EPSD	COSMIC	9.140	Up-regulation
AGC_SGK_SGK1_ST	Q969H0	FBXW7	O00141	SGK1	T692	T692I	692	Missense	central	0	yes	13.642	0.000	EPSD	COSMIC	9.140	Loss
AGC_SGK_SGK1_ST	Q969H0	FBXW7	O00141	SGK1	T692	R689E	689	Missense	distal	-3	no	13.642	3.212	EPSD	COSMIC	9.140	Loss
AGC_SGK_SGK1_ST	Q969H0	FBXW7	O00141	SGK1	T692	V699L	699	Missense	distal	7	no	13.642	13.487	EPSD	COSMIC;GDSC;CCLE	9.140	Down-regulation
AGC_SGK_SGK1_ST	P25963	NFKBIA	O00141	SGK1	S32	M37K	37	Missense	distal	5	no	14.940	15.018	PhosphoSitePlus	COSMIC	9.140	Up-regulation
AGC_SGK_SGK1_ST	P25963	NFKBIA	O00141	SGK1	S32	S36P	36	Missense	distal	4	no	14.940	14.723	PhosphoSitePlus	COSMIC	9.140	Down-regulation
AGC_SGK_SGK1_ST	P25963	NFKBIA	O00141	SGK1	S32	S32N	32	Missense	central	0	yes	14.940	0.000	PhosphoSitePlus	COSMIC	9.140	Loss
TK_Jak_JAK1_Y	Q96EB6	SIRT1	P23458	JAK1	Y280	R282S	282	Missense	proximal	2	no	14.903	15.168	PhosphoSitePlus;EPSD	COSMIC	8.575	Up-regulation
TK_Jak_JAK1_Y	Q96EB6	SIRT1	P23458	JAK1	Y280	R282C	282	Missense	proximal	2	no	14.903	14.312	PhosphoSitePlus;EPSD	COSMIC	8.575	Down-regulation
TK_Jak_JAK1_Y	Q96EB6	SIRT1	P23458	JAK1	Y301	Q294L	294	Missense	distal	-7	no	14.399	15.277	EPSD;PhosphoSitePlus	COSMIC	8.575	Up-regulation
TK_Jak_JAK1_Y	Q9NZJ5	EIF2AK3	P23458	JAK1	Y565	C559F	559	Missense	distal	-6	no	9.587	10.215	EPSD	COSMIC	8.575	Up-regulation
TK_Jak_JAK1_Y	Q9Y5X2	SNX8	P23458	JAK1	Y95	E96D	96	Missense	proximal	1	no	17.912	18.467	PhosphoSitePlus;EPSD	COSMIC	8.575	Up-regulation
TK_Jak_JAK1_Y	Q9Y5X2	SNX8	P23458	JAK1	Y95	S98Y	98	Missense	distal	3	no	17.912	17.803	PhosphoSitePlus;EPSD	COSMIC	8.575	Down-regulation
TK_Jak_JAK1_Y	Q9Y5X2	SNX8	P23458	JAK1	Y126	P125L	125	Missense	proximal	-1	no	14.341	12.539	EPSD;PhosphoSitePlus	COSMIC	8.575	Down-regulation
TK_Jak_JAK1_Y	Q99683	MAP3K5	P23458	JAK1	Y574	Y574F	574	Missense	central	0	yes	8.938	0.000	EPSD	COSMIC	8.575	Loss
TK_Jak_JAK1_Y	Q99683	MAP3K5	P23458	JAK1	Y718	Q720E	720	Missense	proximal	2	no	13.321	13.245	PhosphoSitePlus	COSMIC	8.575	Down-regulation
TK_Jak_JAK1_Y	Q99683	MAP3K5	P23458	JAK1	Y718	R714K	714	Missense	distal	-4	no	13.321	13.485	PhosphoSitePlus	COSMIC	8.575	Up-regulation
TK_Jak_JAK1_Y	Q99683	MAP3K5	P23458	JAK1	Y961	G957E	957	Missense	distal	-4	no	9.213	9.952	EPSD	COSMIC	8.575	Up-regulation
TK_Jak_JAK1_Y	P42224	STAT1	P23458	JAK1	Y701	D694N	694	Missense	distal	-7	no	19.205	19.229	PhosphoSitePlus	COSMIC	8.575	Up-regulation
TK_Jak_JAK1_Y	P42224	STAT1	P23458	JAK1	Y701	K697I	697	Missense	distal	-4	no	19.205	18.717	PhosphoSitePlus	COSMIC	8.575	Down-regulation
Atypical_TAF1_TAF1_ST	P52655	GTF2A1	P21675	TAF1	S280	G277W	277	Missense	distal	-3	no	6.397	6.238	EPSD	COSMIC	2.466	Down-regulation
Atypical_TAF1_TAF1_ST	P52655	GTF2A1	P21675	TAF1	S280	D286H	286	Missense	distal	6	no	6.397	5.018	EPSD	COSMIC	2.466	Down-regulation
Atypical_TAF1_TAF1_ST	P52655	GTF2A1	P21675	TAF1	S281	G277W	277	Missense	distal	-4	no	6.891	7.004	EPSD	COSMIC	2.466	Up-regulation
Atypical_TAF1_TAF1_ST	P52655	GTF2A1	P21675	TAF1	S281	D286H	286	Missense	distal	5	no	6.891	6.965	EPSD	COSMIC	2.466	Up-regulation
Atypical_TAF1_TAF1_ST	P52655	GTF2A1	P21675	TAF1	S316	S321R	321	Missense	distal	5	no	7.437	7.651	EPSD;PhosphoSitePlus	COSMIC	2.466	Up-regulation
Atypical_TAF1_TAF1_ST	P52655	GTF2A1	P21675	TAF1	S316	S321N	321	Missense	distal	5	no	7.437	7.546	EPSD;PhosphoSitePlus	COSMIC	2.466	Up-regulation
Atypical_TAF1_TAF1_ST	P52655	GTF2A1	P21675	TAF1	S321	Q326P	326	Missense	distal	5	no	7.637	7.646	PhosphoSitePlus;EPSD	COSMIC	2.466	Up-regulation
Atypical_TAF1_TAF1_ST	P52655	GTF2A1	P21675	TAF1	S321	S321R	321	Missense	central	0	yes	7.637	0.000	PhosphoSitePlus;EPSD	COSMIC	2.466	Loss
Atypical_TAF1_TAF1_ST	P52655	GTF2A1	P21675	TAF1	S321	S321N	321	Missense	central	0	yes	7.637	0.000	PhosphoSitePlus;EPSD	COSMIC	2.466	Loss
Atypical_TAF1_TAF1_ST	Q15545	TAF7	P21675	TAF1	S171	V166G	166	Missense	distal	-5	no	2.788	3.063	EPSD	COSMIC	2.466	Up-regulation
Atypical_TAF1_TAF1_ST	Q15545	TAF7	P21675	TAF1	S229	T236A	236	Missense	distal	7	no	3.327	3.339	EPSD	COSMIC;GDSC;CCLE	2.466	Up-regulation
Atypical_TAF1_TAF1_ST	Q15545	TAF7	P21675	TAF1	S229	E235D	235	Missense	distal	6	no	3.327	3.391	EPSD	COSMIC	2.466	Up-regulation
Atypical_TAF1_TAF1_ST	Q15545	TAF7	P21675	TAF1	T249	E242D	242	Missense	distal	-7	no	2.218	2.845	EPSD	COSMIC;GDSC;CCLE	2.466	Gain
Atypical_TAF1_TAF1_ST	Q15545	TAF7	P21675	TAF1	S264	K260N	260	Missense	distal	-4	no	7.120	6.796	PhosphoSitePlus	COSMIC	2.466	Down-regulation
Atypical_TAF1_TAF1_ST	Q15545	TAF7	P21675	TAF1	S264	E270Q	270	Missense	distal	6	no	7.120	5.525	PhosphoSitePlus	COSMIC	2.466	Down-regulation
Atypical_TAF1_TAF1_ST	Q15545	TAF7	P21675	TAF1	S264	E266V	266	Missense	proximal	2	no	7.120	6.431	PhosphoSitePlus	COSMIC;GDSC;CCLE	2.466	Down-regulation
Atypical_TAF1_TAF1_ST	Q15545	TAF7	P21675	TAF1	S338	E341K	341	Missense	distal	3	no	2.287	2.482	EPSD	COSMIC	2.466	Gain
Atypical_TAF1_TAF1_ST	P04637	TP53	P21675	TAF1	S46	M40I	40	Missense	distal	-6	no	3.420	3.454	EPSD	COSMIC	2.466	Up-regulation
Atypical_TAF1_TAF1_ST	P04637	TP53	P21675	TAF1	S46	W53C	53	Missense	distal	7	no	3.420	3.396	EPSD	COSMIC	2.466	Down-regulation
Atypical_TAF1_TAF1_ST	P04637	TP53	P21675	TAF1	S46	W53G	53	Missense	distal	7	no	3.420	3.374	EPSD	COSMIC	2.466	Down-regulation
Atypical_TAF1_TAF1_ST	P04637	TP53	P21675	TAF1	S46	S46F	46	Missense	central	0	yes	3.420	0.000	EPSD	COSMIC	2.466	Loss
Atypical_TAF1_TAF1_ST	P04637	TP53	P21675	TAF1	S46	D49Y	49	Missense	distal	3	no	3.420	3.578	EPSD	COSMIC	2.466	Up-regulation
Atypical_TAF1_TAF1_ST	P04637	TP53	P21675	TAF1	S46	P47L	47	Missense	proximal	1	no	3.420	3.113	EPSD	COSMIC	2.466	Down-regulation
Atypical_TAF1_TAF1_ST	P04637	TP53	P21675	TAF1	S46	D49H	49	Missense	distal	3	no	3.420	3.634	EPSD	COSMIC;GDSC;CCLE	2.466	Up-regulation
Atypical_TAF1_TAF1_ST	P04637	TP53	P21675	TAF1	S46	P47S	47	Missense	proximal	1	no	3.420	3.963	EPSD	COSMIC	2.466	Up-regulation
Atypical_TAF1_TAF1_ST	P04637	TP53	P21675	TAF1	S46	D41N	41	Missense	distal	-5	no	3.420	3.422	EPSD	COSMIC	2.466	Up-regulation
Atypical_TAF1_TAF1_ST	P04637	TP53	P21675	TAF1	S46	D48H	48	Missense	proximal	2	no	3.420	2.381	EPSD	COSMIC	2.466	Loss
Atypical_TAF1_TAF1_ST	P04637	TP53	P21675	TAF1	S46	D49N	49	Missense	distal	3	no	3.420	3.643	EPSD	COSMIC	2.466	Up-regulation
Atypical_TAF1_TAF1_ST	P04637	TP53	P21675	TAF1	S46	M44I	44	Missense	proximal	-2	no	3.420	3.691	EPSD	COSMIC	2.466	Up-regulation
Atypical_TAF1_TAF1_ST	P04637	TP53	P21675	TAF1	S46	Q52H	52	Missense	distal	6	no	3.420	3.701	EPSD	COSMIC	2.466	Up-regulation
Atypical_TAF1_TAF1_ST	P04637	TP53	P21675	TAF1	S46	D49V	49	Missense	distal	3	no	3.420	3.610	EPSD	COSMIC	2.466	Up-regulation
Atypical_TAF1_TAF1_ST	P04637	TP53	P21675	TAF1	S46	A39V	39	Missense	distal	-7	no	3.420	3.507	EPSD	COSMIC	2.466	Up-regulation
Atypical_TAF1_TAF1_ST	P04637	TP53	P21675	TAF1	S46	A39S	39	Missense	distal	-7	no	3.420	3.338	EPSD	COSMIC	2.466	Down-regulation
Atypical_TAF1_TAF1_ST	P04637	TP53	P21675	TAF1	S46	D42Y	42	Missense	distal	-4	no	3.420	3.012	EPSD	COSMIC	2.466	Down-regulation
Atypical_TAF1_TAF1_ST	P04637	TP53	P21675	TAF1	S46	M44R	44	Missense	proximal	-2	no	3.420	3.550	EPSD	COSMIC	2.466	Up-regulation
Atypical_TAF1_TAF1_ST	P04637	TP53	P21675	TAF1	S46	S46P	46	Missense	central	0	yes	3.420	0.000	EPSD	COSMIC	2.466	Loss
Atypical_TAF1_TAF1_ST	P04637	TP53	P21675	TAF1	S46	M44V	44	Missense	proximal	-2	no	3.420	3.485	EPSD	COSMIC	2.466	Up-regulation
Atypical_TAF1_TAF1_ST	P04637	TP53	P21675	TAF1	S46	L45P	45	Missense	proximal	-1	no	3.420	3.421	EPSD	COSMIC	2.466	Up-regulation
Atypical_TAF1_TAF1_ST	P04637	TP53	P21675	TAF1	S46	M44T	44	Missense	proximal	-2	no	3.420	3.587	EPSD	COSMIC	2.466	Up-regulation
Atypical_TAF1_TAF1_ST	P04637	TP53	P21675	TAF1	S46	A39T	39	Missense	distal	-7	no	3.420	3.299	EPSD	COSMIC	2.466	Down-regulation
Atypical_TAF1_TAF1_ST	P04637	TP53	P21675	TAF1	S46	L43F	43	Missense	distal	-3	no	3.420	3.123	EPSD	COSMIC	2.466	Down-regulation
Atypical_TAF1_TAF1_ST	P04637	TP53	P21675	TAF1	S46	D41H	41	Missense	distal	-5	no	3.420	3.412	EPSD	COSMIC	2.466	Down-regulation
Atypical_TAF1_TAF1_ST	P04637	TP53	P21675	TAF1	S46	D49E	49	Missense	distal	3	no	3.420	3.401	EPSD	COSMIC	2.466	Down-regulation
Atypical_TAF1_TAF1_ST	P04637	TP53	P21675	TAF1	S46	D49G	49	Missense	distal	3	no	3.420	3.778	EPSD	COSMIC	2.466	Up-regulation
Atypical_TAF1_TAF1_ST	P04637	TP53	P21675	TAF1	S46	D48A	48	Missense	proximal	2	no	3.420	2.670	EPSD	COSMIC	2.466	Down-regulation
Atypical_TAF1_TAF1_ST	P04637	TP53	P21675	TAF1	S46	D48Y	48	Missense	proximal	2	no	3.420	2.585	EPSD	COSMIC	2.466	Down-regulation
Atypical_TAF1_TAF1_ST	P04637	TP53	P21675	TAF1	S46	D48E	48	Missense	proximal	2	no	3.420	3.249	EPSD	COSMIC	2.466	Down-regulation
Atypical_TAF1_TAF1_ST	P04637	TP53	P21675	TAF1	S46	D49I	49	Missense	distal	3	no	3.420	3.741	EPSD	COSMIC	2.466	Up-regulation
Atypical_TAF1_TAF1_ST	P04637	TP53	P21675	TAF1	S46	D41E	41	Missense	distal	-5	no	3.420	3.274	EPSD	COSMIC	2.466	Down-regulation
Atypical_TAF1_TAF1_ST	P04637	TP53	P21675	TAF1	T55	E56K	56	Missense	proximal	1	no	6.462	5.232	PhosphoSitePlus	COSMIC	2.466	Down-regulation
Atypical_TAF1_TAF1_ST	P04637	TP53	P21675	TAF1	T55	W53C	53	Missense	proximal	-2	no	6.462	6.524	PhosphoSitePlus	COSMIC	2.466	Up-regulation
Atypical_TAF1_TAF1_ST	P04637	TP53	P21675	TAF1	T55	W53G	53	Missense	proximal	-2	no	6.462	6.427	PhosphoSitePlus	COSMIC	2.466	Down-regulation
Atypical_TAF1_TAF1_ST	P04637	TP53	P21675	TAF1	T55	P60A	60	Missense	distal	5	no	6.462	6.366	PhosphoSitePlus	COSMIC	2.466	Down-regulation
Atypical_TAF1_TAF1_ST	P04637	TP53	P21675	TAF1	T55	D61N	61	Missense	distal	6	no	6.462	4.976	PhosphoSitePlus	COSMIC	2.466	Down-regulation
Atypical_TAF1_TAF1_ST	P04637	TP53	P21675	TAF1	T55	D49Y	49	Missense	distal	-6	no	6.462	6.460	PhosphoSitePlus	COSMIC	2.466	Down-regulation
Atypical_TAF1_TAF1_ST	P04637	TP53	P21675	TAF1	T55	P58Q	58	Missense	distal	3	no	6.462	6.487	PhosphoSitePlus	COSMIC	2.466	Up-regulation
Atypical_TAF1_TAF1_ST	P04637	TP53	P21675	TAF1	T55	D49H	49	Missense	distal	-6	no	6.462	6.460	PhosphoSitePlus	COSMIC;GDSC;CCLE	2.466	Down-regulation
Atypical_TAF1_TAF1_ST	P04637	TP53	P21675	TAF1	T55	G59N	59	Missense	distal	4	no	6.462	6.252	PhosphoSitePlus	COSMIC	2.466	Down-regulation
Atypical_TAF1_TAF1_ST	P04637	TP53	P21675	TAF1	T55	G59C	59	Missense	distal	4	no	6.462	6.374	PhosphoSitePlus	COSMIC	2.466	Down-regulation
Atypical_TAF1_TAF1_ST	P04637	TP53	P21675	TAF1	T55	P60R	60	Missense	distal	5	no	6.462	6.569	PhosphoSitePlus	COSMIC	2.466	Up-regulation
Atypical_TAF1_TAF1_ST	P04637	TP53	P21675	TAF1	T55	G59D	59	Missense	distal	4	no	6.462	6.045	PhosphoSitePlus	COSMIC	2.466	Down-regulation
Atypical_TAF1_TAF1_ST	P04637	TP53	P21675	TAF1	T55	D48H	48	Missense	distal	-7	no	6.462	6.374	PhosphoSitePlus	COSMIC	2.466	Down-regulation
Atypical_TAF1_TAF1_ST	P04637	TP53	P21675	TAF1	T55	P58L	58	Missense	distal	3	no	6.462	6.567	PhosphoSitePlus	COSMIC	2.466	Up-regulation
Atypical_TAF1_TAF1_ST	P04637	TP53	P21675	TAF1	T55	D61H	61	Missense	distal	6	no	6.462	5.082	PhosphoSitePlus	COSMIC	2.466	Down-regulation
Atypical_TAF1_TAF1_ST	P04637	TP53	P21675	TAF1	T55	Q52H	52	Missense	distal	-3	no	6.462	6.247	PhosphoSitePlus	COSMIC	2.466	Down-regulation
Atypical_TAF1_TAF1_ST	P04637	TP53	P21675	TAF1	T55	F54L	54	Missense	proximal	-1	no	6.462	6.459	PhosphoSitePlus	COSMIC	2.466	Down-regulation
Atypical_TAF1_TAF1_ST	P04637	TP53	P21675	TAF1	T55	D49V	49	Missense	distal	-6	no	6.462	6.467	PhosphoSitePlus	COSMIC	2.466	Up-regulation
Atypical_TAF1_TAF1_ST	P04637	TP53	P21675	TAF1	T55	P60L	60	Missense	distal	5	no	6.462	6.618	PhosphoSitePlus	COSMIC	2.466	Up-regulation
Atypical_TAF1_TAF1_ST	P04637	TP53	P21675	TAF1	T55	P60S	60	Missense	distal	5	no	6.462	6.355	PhosphoSitePlus	COSMIC	2.466	Down-regulation
Atypical_TAF1_TAF1_ST	P04637	TP53	P21675	TAF1	T55	G59R	59	Missense	distal	4	no	6.462	6.321	PhosphoSitePlus	COSMIC	2.466	Down-regulation
Atypical_TAF1_TAF1_ST	P04637	TP53	P21675	TAF1	T55	E56V	56	Missense	proximal	1	no	6.462	5.315	PhosphoSitePlus	COSMIC	2.466	Down-regulation
Atypical_TAF1_TAF1_ST	P04637	TP53	P21675	TAF1	T55	P60T	60	Missense	distal	5	no	6.462	6.543	PhosphoSitePlus	COSMIC	2.466	Up-regulation
Atypical_TAF1_TAF1_ST	P04637	TP53	P21675	TAF1	T55	E62D	62	Missense	distal	7	no	6.462	6.515	PhosphoSitePlus	COSMIC	2.466	Up-regulation
Atypical_TAF1_TAF1_ST	P04637	TP53	P21675	TAF1	T55	P58R	58	Missense	distal	3	no	6.462	6.516	PhosphoSitePlus	COSMIC	2.466	Up-regulation
Atypical_TAF1_TAF1_ST	P04637	TP53	P21675	TAF1	T55	P60Q	60	Missense	distal	5	no	6.462	6.453	PhosphoSitePlus	COSMIC	2.466	Down-regulation
Atypical_TAF1_TAF1_ST	P04637	TP53	P21675	TAF1	T55	P58N	58	Missense	distal	3	no	6.462	6.484	PhosphoSitePlus	COSMIC	2.466	Up-regulation
Atypical_TAF1_TAF1_ST	P04637	TP53	P21675	TAF1	T55	P58S	58	Missense	distal	3	no	6.462	6.373	PhosphoSitePlus	COSMIC	2.466	Down-regulation
Atypical_TAF1_TAF1_ST	P04637	TP53	P21675	TAF1	T55	P58T	58	Missense	distal	3	no	6.462	6.496	PhosphoSitePlus	COSMIC	2.466	Up-regulation
Atypical_TAF1_TAF1_ST	P04637	TP53	P21675	TAF1	T55	D49E	49	Missense	distal	-6	no	6.462	6.422	PhosphoSitePlus	COSMIC	2.466	Down-regulation
Atypical_TAF1_TAF1_ST	P04637	TP53	P21675	TAF1	T55	P58F	58	Missense	distal	3	no	6.462	6.480	PhosphoSitePlus	COSMIC	2.466	Up-regulation
Atypical_TAF1_TAF1_ST	P04637	TP53	P21675	TAF1	T55	D49G	49	Missense	distal	-6	no	6.462	6.480	PhosphoSitePlus	COSMIC	2.466	Up-regulation
Atypical_TAF1_TAF1_ST	P04637	TP53	P21675	TAF1	T55	P60H	60	Missense	distal	5	no	6.462	6.459	PhosphoSitePlus	COSMIC	2.466	Down-regulation
Atypical_TAF1_TAF1_ST	P04637	TP53	P21675	TAF1	T55	P58H	58	Missense	distal	3	no	6.462	6.474	PhosphoSitePlus	COSMIC	2.466	Up-regulation
Atypical_TAF1_TAF1_ST	P04637	TP53	P21675	TAF1	T55	P58A	58	Missense	distal	3	no	6.462	6.400	PhosphoSitePlus	COSMIC	2.466	Down-regulation
Atypical_TAF1_TAF1_ST	P04637	TP53	P21675	TAF1	T55	D48A	48	Missense	distal	-7	no	6.462	6.373	PhosphoSitePlus	COSMIC	2.466	Down-regulation
Atypical_TAF1_TAF1_ST	P04637	TP53	P21675	TAF1	T55	E62G	62	Missense	distal	7	no	6.462	6.348	PhosphoSitePlus	COSMIC	2.466	Down-regulation
Atypical_TAF1_TAF1_ST	P04637	TP53	P21675	TAF1	T55	D48Y	48	Missense	distal	-7	no	6.462	6.292	PhosphoSitePlus	COSMIC	2.466	Down-regulation
Atypical_TAF1_TAF1_ST	P04637	TP53	P21675	TAF1	T55	E62V	62	Missense	distal	7	no	6.462	6.427	PhosphoSitePlus	COSMIC	2.466	Down-regulation
Atypical_TAF1_TAF1_ST	P04637	TP53	P21675	TAF1	T55	D48E	48	Missense	distal	-7	no	6.462	5.835	PhosphoSitePlus	COSMIC	2.466	Down-regulation
Atypical_TAF1_TAF1_ST	P04637	TP53	P21675	TAF1	T55	D49I	49	Missense	distal	-6	no	6.462	6.490	PhosphoSitePlus	COSMIC	2.466	Up-regulation
Atypical_TAF1_TAF1_ST	P04637	TP53	P21675	TAF1	T55	P60C	60	Missense	distal	5	no	6.462	6.556	PhosphoSitePlus	COSMIC	2.466	Up-regulation
Atypical_TAF1_TAF1_ST	P04637	TP53	P21675	TAF1	T125	N131D	131	Missense	distal	6	no	1.766	3.252	EPSD	COSMIC	2.466	Gain
Atypical_TAF1_TAF1_ST	P04637	TP53	P21675	TAF1	S183	G187V	187	Missense	distal	4	no	3.336	3.087	EPSD	COSMIC	2.466	Down-regulation
Atypical_TAF1_TAF1_ST	P04637	TP53	P21675	TAF1	S183	G187D	187	Missense	distal	4	no	3.336	2.919	EPSD	COSMIC	2.466	Down-regulation
Atypical_TAF1_TAF1_ST	P04637	TP53	P21675	TAF1	S183	G187A	187	Missense	distal	4	no	3.336	3.089	EPSD	COSMIC	2.466	Down-regulation
Atypical_TAF1_TAF1_ST	P04637	TP53	P21675	TAF1	S183	S183C	183	Missense	central	0	yes	3.336	0.000	EPSD	COSMIC	2.466	Loss
Atypical_TAF1_TAF1_ST	P04637	TP53	P21675	TAF1	S183	S183P	183	Missense	central	0	yes	3.336	0.000	EPSD	COSMIC	2.466	Loss
Atypical_TAF1_TAF1_ST	P04637	TP53	P21675	TAF1	S183	S185G	185	Missense	proximal	2	no	3.336	2.458	EPSD	COSMIC	2.466	Loss
Atypical_TAF1_TAF1_ST	P04637	TP53	P21675	TAF1	S183	P190N	190	Missense	distal	7	no	3.336	3.312	EPSD	COSMIC	2.466	Down-regulation
Atypical_TAF1_TAF1_ST	P04637	TP53	P21675	TAF1	S183	D184N	184	Missense	proximal	1	no	3.336	1.978	EPSD	COSMIC	2.466	Loss
Atypical_TAF1_TAF1_ST	P04637	TP53	P21675	TAF1	S183	S185R	185	Missense	proximal	2	no	3.336	2.898	EPSD	COSMIC	2.466	Down-regulation
Atypical_TAF1_TAF1_ST	P04637	TP53	P21675	TAF1	S183	S183L	183	Missense	central	0	yes	3.336	0.000	EPSD	COSMIC	2.466	Loss
Atypical_TAF1_TAF1_ST	P04637	TP53	P21675	TAF1	S183	R181L	181	Missense	proximal	-2	no	3.336	3.434	EPSD	COSMIC	2.466	Up-regulation
Atypical_TAF1_TAF1_ST	P04637	TP53	P21675	TAF1	S183	H178P	178	Missense	distal	-5	no	3.336	3.346	EPSD	COSMIC	2.466	Up-regulation
Atypical_TAF1_TAF1_ST	P04637	TP53	P21675	TAF1	S183	D186N	186	Missense	distal	3	no	3.336	3.559	EPSD	COSMIC	2.466	Up-regulation
Atypical_TAF1_TAF1_ST	P04637	TP53	P21675	TAF1	S183	A189S	189	Missense	distal	6	no	3.336	3.526	EPSD	COSMIC	2.466	Up-regulation
Atypical_TAF1_TAF1_ST	P04637	TP53	P21675	TAF1	S183	H178L	178	Missense	distal	-5	no	3.336	3.523	EPSD	COSMIC	2.466	Up-regulation
Atypical_TAF1_TAF1_ST	P04637	TP53	P21675	TAF1	S183	D184Y	184	Missense	proximal	1	no	3.336	2.358	EPSD	COSMIC	2.466	Loss
Atypical_TAF1_TAF1_ST	P04637	TP53	P21675	TAF1	S183	L188V	188	Missense	distal	5	no	3.336	3.168	EPSD	COSMIC	2.466	Down-regulation
Atypical_TAF1_TAF1_ST	P04637	TP53	P21675	TAF1	S183	A189V	189	Missense	distal	6	no	3.336	3.136	EPSD	COSMIC	2.466	Down-regulation
Atypical_TAF1_TAF1_ST	P04637	TP53	P21675	TAF1	S183	H178Y	178	Missense	distal	-5	no	3.336	3.426	EPSD	COSMIC	2.466	Up-regulation
Atypical_TAF1_TAF1_ST	P04637	TP53	P21675	TAF1	S183	D186E	186	Missense	distal	3	no	3.336	3.317	EPSD	COSMIC	2.466	Down-regulation
Atypical_TAF1_TAF1_ST	P04637	TP53	P21675	TAF1	S183	C182Y	182	Missense	proximal	-1	no	3.336	3.333	EPSD	COSMIC	2.466	Down-regulation
Atypical_TAF1_TAF1_ST	P04637	TP53	P21675	TAF1	S183	D186H	186	Missense	distal	3	no	3.336	3.549	EPSD	COSMIC	2.466	Up-regulation
Atypical_TAF1_TAF1_ST	P04637	TP53	P21675	TAF1	S183	L188Q	188	Missense	distal	5	no	3.336	3.171	EPSD	COSMIC	2.466	Down-regulation
Atypical_TAF1_TAF1_ST	P04637	TP53	P21675	TAF1	S183	H178N	178	Missense	distal	-5	no	3.336	3.346	EPSD	COSMIC	2.466	Up-regulation
Atypical_TAF1_TAF1_ST	P04637	TP53	P21675	TAF1	S183	G187R	187	Missense	distal	4	no	3.336	3.195	EPSD	COSMIC;GDSC	2.466	Down-regulation
Atypical_TAF1_TAF1_ST	P04637	TP53	P21675	TAF1	S183	C182S	182	Missense	proximal	-1	no	3.336	3.332	EPSD	COSMIC	2.466	Down-regulation
Atypical_TAF1_TAF1_ST	P04637	TP53	P21675	TAF1	S183	P190F	190	Missense	distal	7	no	3.336	3.313	EPSD	COSMIC	2.466	Down-regulation
Atypical_TAF1_TAF1_ST	P04637	TP53	P21675	TAF1	S183	G187C	187	Missense	distal	4	no	3.336	3.248	EPSD	COSMIC	2.466	Down-regulation
Atypical_TAF1_TAF1_ST	P04637	TP53	P21675	TAF1	S183	S185T	185	Missense	proximal	2	no	3.336	2.957	EPSD	COSMIC	2.466	Down-regulation
Atypical_TAF1_TAF1_ST	P04637	TP53	P21675	TAF1	S183	P190H	190	Missense	distal	7	no	3.336	3.303	EPSD	COSMIC	2.466	Down-regulation
Atypical_TAF1_TAF1_ST	P04637	TP53	P21675	TAF1	S183	S185N	185	Missense	proximal	2	no	3.336	2.912	EPSD	COSMIC	2.466	Down-regulation
Atypical_TAF1_TAF1_ST	P04637	TP53	P21675	TAF1	S183	D186G	186	Missense	distal	3	no	3.336	3.694	EPSD	COSMIC	2.466	Up-regulation
Atypical_TAF1_TAF1_ST	P04637	TP53	P21675	TAF1	S183	D186V	186	Missense	distal	3	no	3.336	3.526	EPSD	COSMIC	2.466	Up-regulation
Atypical_TAF1_TAF1_ST	P04637	TP53	P21675	TAF1	S183	P177I	177	Missense	distal	-6	no	3.336	3.364	EPSD	COSMIC	2.466	Up-regulation
Atypical_TAF1_TAF1_ST	P04637	TP53	P21675	TAF1	S183	P190A	190	Missense	distal	7	no	3.336	3.338	EPSD	COSMIC	2.466	Up-regulation
Atypical_TAF1_TAF1_ST	P04637	TP53	P21675	TAF1	S183	S185C	185	Missense	proximal	2	no	3.336	2.787	EPSD	COSMIC	2.466	Down-regulation
Atypical_TAF1_TAF1_ST	P04637	TP53	P21675	TAF1	S183	S185I	185	Missense	proximal	2	no	3.336	2.615	EPSD	COSMIC	2.466	Down-regulation
Atypical_TAF1_TAF1_ST	P04637	TP53	P21675	TAF1	S183	A189P	189	Missense	distal	6	no	3.336	2.970	EPSD	COSMIC	2.466	Down-regulation
Atypical_TAF1_TAF1_ST	P04637	TP53	P21675	TAF1	S183	E180Q	180	Missense	distal	-3	no	3.336	3.802	EPSD	COSMIC	2.466	Up-regulation
Atypical_TAF1_TAF1_ST	P04637	TP53	P21675	TAF1	S183	R181S	181	Missense	proximal	-2	no	3.336	3.145	EPSD	COSMIC	2.466	Down-regulation
Atypical_TAF1_TAF1_ST	P04637	TP53	P21675	TAF1	S183	C182R	182	Missense	proximal	-1	no	3.336	3.334	EPSD	COSMIC	2.466	Down-regulation
Atypical_TAF1_TAF1_ST	P04637	TP53	P21675	TAF1	S183	E180G	180	Missense	distal	-3	no	3.336	3.862	EPSD	COSMIC	2.466	Up-regulation
Atypical_TAF1_TAF1_ST	P04637	TP53	P21675	TAF1	S183	L188M	188	Missense	distal	5	no	3.336	3.147	EPSD	COSMIC	2.466	Down-regulation
Atypical_TAF1_TAF1_ST	P04637	TP53	P21675	TAF1	S183	P177F	177	Missense	distal	-6	no	3.336	3.340	EPSD	COSMIC	2.466	Up-regulation
Atypical_TAF1_TAF1_ST	P04637	TP53	P21675	TAF1	S183	D184E	184	Missense	proximal	1	no	3.336	3.250	EPSD	COSMIC	2.466	Down-regulation
Atypical_TAF1_TAF1_ST	P04637	TP53	P21675	TAF1	S183	A189G	189	Missense	distal	6	no	3.336	2.346	EPSD	COSMIC	2.466	Loss
Atypical_TAF1_TAF1_ST	P04637	TP53	P21675	TAF1	S183	R181G	181	Missense	proximal	-2	no	3.336	3.376	EPSD	COSMIC	2.466	Up-regulation
Atypical_TAF1_TAF1_ST	P04637	TP53	P21675	TAF1	S183	D186X	186	Missense	distal	3	no	3.336	3.537	EPSD	COSMIC	2.466	Up-regulation
Atypical_TAF1_TAF1_ST	P04637	TP53	P21675	TAF1	S183	R181Y	181	Missense	proximal	-2	no	3.336	3.248	EPSD	COSMIC	2.466	Down-regulation
Atypical_TAF1_TAF1_ST	P04637	TP53	P21675	TAF1	S183	D184G	184	Missense	proximal	1	no	3.336	1.421	EPSD	COSMIC	2.466	Loss
Atypical_TAF1_TAF1_ST	P04637	TP53	P21675	TAF1	S215	V217E	217	Missense	proximal	2	no	1.839	2.528	EPSD	COSMIC	2.466	Gain
Atypical_TAF1_TAF1_ST	P04637	TP53	P21675	TAF1	T304	N310D	310	Missense	distal	6	no	1.123	2.609	EPSD	COSMIC	2.466	Gain
Atypical_TAF1_TAF1_ST	P04637	TP53	P21675	TAF1	S313	N310T	310	Missense	distal	-3	no	3.173	3.286	EPSD	COSMIC	2.466	Up-regulation
Atypical_TAF1_TAF1_ST	P04637	TP53	P21675	TAF1	S313	Q317R	317	Missense	distal	4	no	3.173	3.168	EPSD	COSMIC	2.466	Down-regulation
Atypical_TAF1_TAF1_ST	P04637	TP53	P21675	TAF1	S313	P309S	309	Missense	distal	-4	no	3.173	3.025	EPSD	COSMIC;GDSC;CCLE	2.466	Down-regulation
Atypical_TAF1_TAF1_ST	P04637	TP53	P21675	TAF1	S313	K319E	319	Missense	distal	6	no	3.173	4.549	EPSD	COSMIC	2.466	Up-regulation
Atypical_TAF1_TAF1_ST	P04637	TP53	P21675	TAF1	S313	K320N	320	Missense	distal	7	no	3.173	3.132	EPSD	COSMIC;GDSC;CCLE	2.466	Down-regulation
Atypical_TAF1_TAF1_ST	P04637	TP53	P21675	TAF1	S313	N310L	310	Missense	distal	-3	no	3.173	3.524	EPSD	COSMIC	2.466	Up-regulation
Atypical_TAF1_TAF1_ST	P04637	TP53	P21675	TAF1	S313	T312S	312	Missense	proximal	-1	no	3.173	3.176	EPSD	COSMIC	2.466	Up-regulation
Atypical_TAF1_TAF1_ST	P04637	TP53	P21675	TAF1	S313	N311Y	311	Missense	proximal	-2	no	3.173	3.090	EPSD	COSMIC	2.466	Down-regulation
Atypical_TAF1_TAF1_ST	P04637	TP53	P21675	TAF1	S313	R306P	306	Missense	distal	-7	no	3.173	3.256	EPSD	COSMIC	2.466	Up-regulation
Atypical_TAF1_TAF1_ST	P04637	TP53	P21675	TAF1	S313	A307T	307	Missense	distal	-6	no	3.173	3.172	EPSD	COSMIC	2.466	Down-regulation
Atypical_TAF1_TAF1_ST	P04637	TP53	P21675	TAF1	S313	N311K	311	Missense	proximal	-2	no	3.173	3.333	EPSD	COSMIC	2.466	Up-regulation
Atypical_TAF1_TAF1_ST	P04637	TP53	P21675	TAF1	S313	Q317K	317	Missense	distal	4	no	3.173	2.985	EPSD	COSMIC	2.466	Down-regulation
Atypical_TAF1_TAF1_ST	P04637	TP53	P21675	TAF1	S313	S315P	315	Missense	proximal	2	no	3.173	2.822	EPSD	COSMIC	2.466	Down-regulation
Atypical_TAF1_TAF1_ST	P04637	TP53	P21675	TAF1	S313	N310H	310	Missense	distal	-3	no	3.173	3.176	EPSD	COSMIC	2.466	Up-regulation
Atypical_TAF1_TAF1_ST	P04637	TP53	P21675	TAF1	S313	R306Q	306	Missense	distal	-7	no	3.173	3.211	EPSD	COSMIC	2.466	Up-regulation
Atypical_TAF1_TAF1_ST	P04637	TP53	P21675	TAF1	S313	S314C	314	Missense	proximal	1	no	3.173	2.441	EPSD	COSMIC	2.466	Loss
Atypical_TAF1_TAF1_ST	P04637	TP53	P21675	TAF1	S313	P318A	318	Missense	distal	5	no	3.173	3.078	EPSD	COSMIC	2.466	Down-regulation
Atypical_TAF1_TAF1_ST	P04637	TP53	P21675	TAF1	S313	P316L	316	Missense	distal	3	no	3.173	3.279	EPSD	COSMIC	2.466	Up-regulation
Atypical_TAF1_TAF1_ST	P04637	TP53	P21675	TAF1	S313	L308M	308	Missense	distal	-5	no	3.173	2.992	EPSD	COSMIC	2.466	Down-regulation
Atypical_TAF1_TAF1_ST	P04637	TP53	P21675	TAF1	S313	S313C	313	Missense	central	0	yes	3.173	0.000	EPSD	COSMIC	2.466	Loss
Atypical_TAF1_TAF1_ST	P04637	TP53	P21675	TAF1	S313	N311H	311	Missense	proximal	-2	no	3.173	3.079	EPSD	COSMIC	2.466	Down-regulation
Atypical_TAF1_TAF1_ST	P04637	TP53	P21675	TAF1	S313	L308V	308	Missense	distal	-5	no	3.173	2.954	EPSD	COSMIC	2.466	Down-regulation
Atypical_TAF1_TAF1_ST	P04637	TP53	P21675	TAF1	S313	S314F	314	Missense	proximal	1	no	3.173	2.649	EPSD	COSMIC	2.466	Down-regulation
Atypical_TAF1_TAF1_ST	P04637	TP53	P21675	TAF1	S313	K319R	319	Missense	distal	6	no	3.173	3.092	EPSD	COSMIC	2.466	Down-regulation
Atypical_TAF1_TAF1_ST	P04637	TP53	P21675	TAF1	S313	T312A	312	Missense	proximal	-1	no	3.173	3.172	EPSD	COSMIC	2.466	Down-regulation
Atypical_TAF1_TAF1_ST	P04637	TP53	P21675	TAF1	S313	N310D	310	Missense	distal	-3	no	3.173	3.499	EPSD	COSMIC	2.466	Up-regulation
Atypical_TAF1_TAF1_ST	P04637	TP53	P21675	TAF1	S313	N311D	311	Missense	proximal	-2	no	3.173	3.242	EPSD	COSMIC	2.466	Up-regulation
Atypical_TAF1_TAF1_ST	P04637	TP53	P21675	TAF1	S313	P309R	309	Missense	distal	-4	no	3.173	2.896	EPSD	COSMIC	2.466	Down-regulation
Atypical_TAF1_TAF1_ST	P04637	TP53	P21675	TAF1	S313	S313N	313	Missense	central	0	yes	3.173	0.000	EPSD	COSMIC	2.466	Loss
Atypical_TAF1_TAF1_ST	P04637	TP53	P21675	TAF1	S313	Q317P	317	Missense	distal	4	no	3.173	3.131	EPSD	COSMIC	2.466	Down-regulation
Atypical_TAF1_TAF1_ST	P04637	TP53	P21675	TAF1	S313	A307S	307	Missense	distal	-6	no	3.173	3.150	EPSD	COSMIC	2.466	Down-regulation
Atypical_TAF1_TAF1_ST	P04637	TP53	P21675	TAF1	S313	P316S	316	Missense	distal	3	no	3.173	3.085	EPSD	COSMIC	2.466	Down-regulation
Atypical_TAF1_TAF1_ST	P04637	TP53	P21675	TAF1	T387	P390L	390	Missense	distal	3	no	2.456	2.562	EPSD	COSMIC	2.466	Gain
Atypical_TAF1_TAF1_ST	P04637	TP53	P21675	TAF1	T387	L383F	383	Missense	distal	-4	no	2.456	2.540	EPSD	COSMIC	2.466	Gain
Atypical_TAF1_TAF1_ST	P04637	TP53	P21675	TAF1	T387	S392P	392	Missense	distal	5	no	2.456	2.562	EPSD	COSMIC	2.466	Gain
Atypical_TAF1_TAF1_ST	P04637	TP53	P21675	TAF1	T387	G389E	389	Missense	proximal	2	no	2.456	3.823	EPSD	COSMIC	2.466	Gain
Atypical_TAF1_TAF1_ST	P04637	TP53	P21675	TAF1	T387	S392L	392	Missense	distal	5	no	2.456	2.718	EPSD	COSMIC	2.466	Gain
Atypical_TAF1_TAF1_ST	P04637	TP53	P21675	TAF1	T387	M384I	384	Missense	distal	-3	no	2.456	2.692	EPSD	COSMIC	2.466	Gain
Atypical_TAF1_TAF1_ST	P04637	TP53	P21675	TAF1	T387	D391N	391	Missense	distal	4	no	2.456	2.663	EPSD	COSMIC	2.466	Gain
Atypical_TAF1_TAF1_ST	P04637	TP53	P21675	TAF1	T387	D391Y	391	Missense	distal	4	no	2.456	2.694	EPSD	COSMIC	2.466	Gain
Atypical_TAF1_TAF1_ST	P04637	TP53	P21675	TAF1	T387	G389V	389	Missense	proximal	2	no	2.456	3.134	EPSD	COSMIC	2.466	Gain
Atypical_TAF1_TAF1_ST	P04637	TP53	P21675	TAF1	S392	P390L	390	Missense	proximal	-2	no	2.497	2.596	EPSD	COSMIC	2.466	Up-regulation
Atypical_TAF1_TAF1_ST	P04637	TP53	P21675	TAF1	S392	S392P	392	Missense	central	0	yes	2.497	0.000	EPSD	COSMIC	2.466	Loss
Atypical_TAF1_TAF1_ST	P04637	TP53	P21675	TAF1	S392	K386N	386	Missense	distal	-6	no	2.497	2.502	EPSD	COSMIC	2.466	Up-regulation
Atypical_TAF1_TAF1_ST	P04637	TP53	P21675	TAF1	S392	G389E	389	Missense	distal	-3	no	2.497	1.971	EPSD	COSMIC	2.466	Loss
Atypical_TAF1_TAF1_ST	P04637	TP53	P21675	TAF1	S392	S392L	392	Missense	central	0	yes	2.497	0.000	EPSD	COSMIC	2.466	Loss
Atypical_TAF1_TAF1_ST	P04637	TP53	P21675	TAF1	S392	D391N	391	Missense	proximal	-1	no	2.497	2.504	EPSD	COSMIC	2.466	Up-regulation
Atypical_TAF1_TAF1_ST	P04637	TP53	P21675	TAF1	S392	D391Y	391	Missense	proximal	-1	no	2.497	2.504	EPSD	COSMIC	2.466	Up-regulation
Atypical_TAF1_TAF1_ST	P04637	TP53	P21675	TAF1	S392	G389V	389	Missense	distal	-3	no	2.497	2.291	EPSD	COSMIC	2.466	Loss
AGC_MAST_MASTL_MASTL_ST	O43768	ENSA	Q96GX5	MASTL	S67	A73V	73	Missense	distal	6	no	31.172	30.829	PhosphoSitePlus	COSMIC	1.338	Down-regulation
AGC_MAST_MASTL_MASTL_ST	O43768	ENSA	Q96GX5	MASTL	S67	A73T	73	Missense	distal	6	no	31.172	30.841	PhosphoSitePlus	COSMIC	1.338	Down-regulation
TK_Abl_ABL1_Y	P37840	SNCA	P00519	ABL1	Y39	E35D	35	Missense	distal	-4	no	8.108	6.822	PhosphoSitePlus;EPSD	COSMIC	7.039	Loss
TK_Abl_ABL1_Y	P37840	SNCA	P00519	ABL1	Y39	S42Y	42	Missense	distal	3	no	8.108	7.605	PhosphoSitePlus;EPSD	COSMIC	7.039	Down-regulation
TK_Abl_ABL1_Y	P37840	SNCA	P00519	ABL1	Y125	A124S	124	Missense	proximal	-1	no	11.633	10.007	EPSD;PhosphoSitePlus	COSMIC	7.039	Down-regulation
TK_Abl_ABL1_Y	P37840	SNCA	P00519	ABL1	Y125	E130V	130	Missense	distal	5	no	11.633	11.849	EPSD;PhosphoSitePlus	COSMIC	7.039	Up-regulation
TK_Abl_ABL1_Y	P37840	SNCA	P00519	ABL1	Y125	E130A	130	Missense	distal	5	no	11.633	11.920	EPSD;PhosphoSitePlus	COSMIC	7.039	Up-regulation
TK_Abl_ABL1_Y	P37840	SNCA	P00519	ABL1	Y125	D121Y	121	Missense	distal	-4	no	11.633	12.077	EPSD;PhosphoSitePlus	COSMIC	7.039	Up-regulation
TK_Abl_ABL1_Y	P37840	SNCA	P00519	ABL1	Y125	E123K	123	Missense	proximal	-2	no	11.633	10.961	EPSD;PhosphoSitePlus	COSMIC	7.039	Down-regulation
TK_Abl_ABL1_Y	P37840	SNCA	P00519	ABL1	Y125	D121E	121	Missense	distal	-4	no	11.633	12.919	EPSD;PhosphoSitePlus	COSMIC	7.039	Up-regulation
TK_Abl_ABL1_Y	P37840	SNCA	P00519	ABL1	Y136	E130V	130	Missense	distal	-6	no	8.117	7.966	EPSD	COSMIC	7.039	Down-regulation
TK_Abl_ABL1_Y	P37840	SNCA	P00519	ABL1	Y136	D135E	135	Missense	proximal	-1	no	8.117	8.798	EPSD	COSMIC;GDSC;CCLE	7.039	Up-regulation
TK_Abl_ABL1_Y	P37840	SNCA	P00519	ABL1	Y136	E130A	130	Missense	distal	-6	no	8.117	7.945	EPSD	COSMIC	7.039	Down-regulation
TK_Abl_ABL1_Y	P15941	MUC1	P00519	ABL1	Y1229	P1228R	1228	Missense	proximal	-1	no	11.239	9.427	EPSD	COSMIC	7.039	Down-regulation
TK_Abl_ABL1_Y	P46937	YAP1	P00519	ABL1	Y407	R411Q	411	Missense	distal	4	no	7.992	7.439	PhosphoSitePlus	COSMIC	7.039	Down-regulation
TK_Abl_ABL1_Y	O94875	SORBS2	P00519	ABL1	Y118	D114A	114	Missense	distal	-4	no	7.390	7.102	EPSD	COSMIC	7.039	Down-regulation
TK_Abl_ABL1_Y	O94875	SORBS2	P00519	ABL1	Y118	D112Y	112	Missense	distal	-6	no	7.390	7.239	EPSD	COSMIC	7.039	Down-regulation
TK_Abl_ABL1_Y	O94875	SORBS2	P00519	ABL1	Y118	Y124C	124	Missense	distal	6	no	7.390	6.843	EPSD	COSMIC	7.039	Loss
TK_Abl_ABL1_Y	O94875	SORBS2	P00519	ABL1	Y118	D114G	114	Missense	distal	-4	no	7.390	7.629	EPSD	COSMIC	7.039	Up-regulation
TK_Abl_ABL1_Y	O94875	SORBS2	P00519	ABL1	Y118	P111L	111	Missense	distal	-7	no	7.390	7.200	EPSD	COSMIC	7.039	Down-regulation
TK_Abl_ABL1_Y	O94875	SORBS2	P00519	ABL1	Y118	T120A	120	Missense	proximal	2	no	7.390	7.584	EPSD	COSMIC	7.039	Up-regulation
TK_Abl_ABL1_Y	O94875	SORBS2	P00519	ABL1	Y118	D114N	114	Missense	distal	-4	no	7.390	7.768	EPSD	COSMIC	7.039	Up-regulation
TK_Abl_ABL1_Y	O94875	SORBS2	P00519	ABL1	Y118	D113N	113	Missense	distal	-5	no	7.390	7.157	EPSD	COSMIC	7.039	Down-regulation
TK_Abl_ABL1_Y	O94875	SORBS2	P00519	ABL1	Y129	G127V	127	Missense	proximal	-2	no	8.818	8.942	EPSD	COSMIC	7.039	Up-regulation
TK_Abl_ABL1_Y	O94875	SORBS2	P00519	ABL1	Y129	Y124C	124	Missense	distal	-5	no	8.818	7.817	EPSD	COSMIC	7.039	Down-regulation
TK_Abl_ABL1_Y	O94875	SORBS2	P00519	ABL1	Y129	G127S	127	Missense	proximal	-2	no	8.818	9.134	EPSD	COSMIC	7.039	Up-regulation
TK_Abl_ABL1_Y	O94875	SORBS2	P00519	ABL1	Y146	K142N	142	Missense	distal	-4	no	5.434	7.192	EPSD	COSMIC	7.039	Gain
TK_Abl_ABL1_Y	O94875	SORBS2	P00519	ABL1	Y232	R227L	227	Missense	distal	-5	no	7.086	5.411	EPSD	COSMIC	7.039	Loss
TK_Abl_ABL1_Y	O94875	SORBS2	P00519	ABL1	Y232	S234G	234	Missense	proximal	2	no	7.086	6.296	EPSD	COSMIC	7.039	Loss
TK_Abl_ABL1_Y	O94875	SORBS2	P00519	ABL1	Y232	D237N	237	Missense	distal	5	no	7.086	6.428	EPSD	COSMIC	7.039	Loss
TK_Abl_ABL1_Y	O94875	SORBS2	P00519	ABL1	Y232	A229V	229	Missense	distal	-3	no	7.086	6.571	EPSD	COSMIC	7.039	Loss
TK_Abl_ABL1_Y	O94875	SORBS2	P00519	ABL1	Y232	D237H	237	Missense	distal	5	no	7.086	7.150	EPSD	COSMIC	7.039	Up-regulation
TK_Abl_ABL1_Y	O94875	SORBS2	P00519	ABL1	Y232	E226K	226	Missense	distal	-6	no	7.086	6.876	EPSD	COSMIC	7.039	Loss
TK_Abl_ABL1_Y	O94875	SORBS2	P00519	ABL1	Y1007	P1013Q	1013	Missense	distal	6	no	7.264	8.009	EPSD	COSMIC	7.039	Up-regulation
TK_Abl_ABL1_Y	O94875	SORBS2	P00519	ABL1	Y1007	Y1007H	1007	Missense	central	0	yes	7.264	0.000	EPSD	COSMIC	7.039	Loss
TK_Abl_ABL1_Y	O94875	SORBS2	P00519	ABL1	Y1007	P1011S	1011	Missense	distal	4	no	7.264	6.984	EPSD	COSMIC	7.039	Loss
TK_Abl_ABL1_Y	Q9UL17	TBX21	P00519	ABL1	Y118	G116V	116	Missense	proximal	-2	no	7.053	7.178	EPSD	COSMIC	7.039	Up-regulation
TK_Abl_ABL1_Y	Q9UL17	TBX21	P00519	ABL1	Y118	R114C	114	Missense	distal	-4	no	7.053	6.097	EPSD	COSMIC;CCLE	7.039	Loss
TK_Abl_ABL1_Y	Q9UL17	TBX21	P00519	ABL1	Y118	P121R	121	Missense	distal	3	no	7.053	2.412	EPSD	COSMIC	7.039	Loss
TK_Abl_ABL1_Y	Q9UL17	TBX21	P00519	ABL1	Y125	P128L	128	Missense	distal	3	no	10.001	7.424	EPSD	COSMIC	7.039	Down-regulation
TK_Abl_ABL1_Y	Q9UL17	TBX21	P00519	ABL1	Y125	P121R	121	Missense	distal	-4	no	10.001	10.043	EPSD	COSMIC	7.039	Up-regulation
TK_Abl_ABL1_Y	Q9UL17	TBX21	P00519	ABL1	Y220	V221D	221	Missense	proximal	1	no	10.447	10.790	EPSD;PhosphoSitePlus	COSMIC;GDSC;CCLE	7.039	Up-regulation
TK_Abl_ABL1_Y	Q9UL17	TBX21	P00519	ABL1	Y220	R218H	218	Missense	proximal	-2	no	10.447	10.898	EPSD;PhosphoSitePlus	COSMIC	7.039	Up-regulation
TK_Abl_ABL1_Y	Q9UL17	TBX21	P00519	ABL1	Y220	L219P	219	Missense	proximal	-1	no	10.447	10.556	EPSD;PhosphoSitePlus	COSMIC	7.039	Up-regulation
TK_Abl_ABL1_Y	Q9UL17	TBX21	P00519	ABL1	Y305	A301V	301	Missense	distal	-4	no	7.037	7.260	PhosphoSitePlus;EPSD	COSMIC	7.039	Gain
TK_Abl_ABL1_Y	Q15746	MYLK	P00519	ABL1	Y231	D226Y	226	Missense	distal	-5	no	7.896	7.215	EPSD;PhosphoSitePlus	COSMIC	7.039	Down-regulation
TK_Abl_ABL1_Y	Q15746	MYLK	P00519	ABL1	Y231	D226E	226	Missense	distal	-5	no	7.896	7.955	EPSD;PhosphoSitePlus	COSMIC	7.039	Up-regulation
TK_Abl_ABL1_Y	Q15746	MYLK	P00519	ABL1	Y231	Q225H	225	Missense	distal	-6	no	7.896	7.786	EPSD;PhosphoSitePlus	COSMIC	7.039	Down-regulation
TK_Abl_ABL1_Y	Q15746	MYLK	P00519	ABL1	Y231	G238R	238	Missense	distal	7	no	7.896	7.924	EPSD;PhosphoSitePlus	COSMIC	7.039	Up-regulation
TK_Abl_ABL1_Y	Q15746	MYLK	P00519	ABL1	Y611	Y611C	611	Missense	central	0	yes	9.079	0.000	EPSD;PhosphoSitePlus	COSMIC	7.039	Loss
TK_Abl_ABL1_Y	Q15746	MYLK	P00519	ABL1	Y611	K608T	608	Missense	distal	-3	no	9.079	9.214	EPSD;PhosphoSitePlus	COSMIC	7.039	Up-regulation
TK_Abl_ABL1_Y	Q15746	MYLK	P00519	ABL1	Y611	P617S	617	Missense	distal	6	no	9.079	9.107	EPSD;PhosphoSitePlus	COSMIC	7.039	Up-regulation
TK_Abl_ABL1_Y	Q15746	MYLK	P00519	ABL1	Y792	W787L	787	Missense	distal	-5	no	8.354	9.213	EPSD;PhosphoSitePlus	COSMIC	7.039	Up-regulation
TK_Abl_ABL1_Y	Q15746	MYLK	P00519	ABL1	Y1449	E1442G	1442	Missense	distal	-7	no	7.716	7.731	PhosphoSitePlus;EPSD	COSMIC	7.039	Up-regulation
TK_Abl_ABL1_Y	Q15746	MYLK	P00519	ABL1	Y1449	V1452M	1452	Missense	distal	3	no	7.716	6.708	PhosphoSitePlus;EPSD	COSMIC	7.039	Loss
TK_Abl_ABL1_Y	Q15746	MYLK	P00519	ABL1	Y1449	D1448H	1448	Missense	proximal	-1	no	7.716	8.065	PhosphoSitePlus;EPSD	COSMIC	7.039	Up-regulation
TK_Abl_ABL1_Y	Q15746	MYLK	P00519	ABL1	Y1575	G1572R	1572	Missense	distal	-3	no	8.886	9.062	EPSD;PhosphoSitePlus	COSMIC	7.039	Up-regulation
TK_Abl_ABL1_Y	Q15746	MYLK	P00519	ABL1	Y1635	T1642M	1642	Missense	distal	7	no	7.901	7.895	EPSD;PhosphoSitePlus	COSMIC	7.039	Down-regulation
TK_Abl_ABL1_Y	Q15746	MYLK	P00519	ABL1	Y1835	G1834E	1834	Missense	proximal	-1	no	6.424	9.154	EPSD	COSMIC	7.039	Gain
TK_Abl_ABL1_Y	P00519	ABL1	P00519	ABL1	Y139	A137S	137	Missense	proximal	-2	no	6.852	7.503	EPSD	COSMIC	7.039	Gain
TK_Abl_ABL1_Y	P00519	ABL1	P00519	ABL1	Y185	R191C	191	Missense	distal	6	no	7.607	6.897	EPSD	COSMIC	7.039	Loss
TK_Abl_ABL1_Y	P00519	ABL1	P00519	ABL1	Y185	S187F	187	Missense	proximal	2	no	7.607	6.710	EPSD	COSMIC	7.039	Loss
TK_Abl_ABL1_Y	P00519	ABL1	P00519	ABL1	Y185	L184R	184	Missense	proximal	-1	no	7.607	5.903	EPSD	COSMIC	7.039	Loss
TK_Abl_ABL1_Y	P00519	ABL1	P00519	ABL1	Y226	R220H	220	Missense	distal	-6	no	7.319	7.147	EPSD	COSMIC	7.039	Down-regulation
TK_Abl_ABL1_Y	P00519	ABL1	P00519	ABL1	Y226	N231S	231	Missense	distal	5	no	7.319	7.745	EPSD	COSMIC	7.039	Up-regulation
TK_Abl_ABL1_Y	P00519	ABL1	P00519	ABL1	Y226	G227S	227	Missense	proximal	1	no	7.319	7.549	EPSD	COSMIC	7.039	Up-regulation
TK_Abl_ABL1_Y	P00519	ABL1	P00519	ABL1	Y226	N231K	231	Missense	distal	5	no	7.319	8.314	EPSD	COSMIC	7.039	Up-regulation
TK_Abl_ABL1_Y	P00519	ABL1	P00519	ABL1	Y253	Q252H	252	Missense	proximal	-1	no	5.852	7.070	EPSD	COSMIC	7.039	Gain
TK_Abl_ABL1_Y	P00519	ABL1	P00519	ABL1	Y253	L248V	248	Missense	distal	-5	no	5.852	7.216	EPSD	COSMIC	7.039	Gain
TK_Abl_ABL1_Y	P00519	ABL1	P00519	ABL1	Y253	Q252E	252	Missense	proximal	-1	no	5.852	7.402	EPSD	COSMIC	7.039	Gain
TK_Abl_ABL1_Y	P00519	ABL1	P00519	ABL1	Y253	Q252P	252	Missense	proximal	-1	no	5.852	7.115	EPSD	COSMIC	7.039	Gain
TK_Abl_ABL1_Y	P00519	ABL1	P00519	ABL1	Y253	L248R	248	Missense	distal	-5	no	5.852	7.527	EPSD	COSMIC	7.039	Gain
TK_Abl_ABL1_Y	P00519	ABL1	P00519	ABL1	Y257	E258A	258	Missense	proximal	1	no	5.973	7.079	EPSD	COSMIC	7.039	Gain
TK_Abl_ABL1_Y	P00519	ABL1	P00519	ABL1	Y320	T319I	319	Missense	proximal	-1	no	5.575	7.492	EPSD	COSMIC	7.039	Gain
TK_Abl_ABL1_Y	P00519	ABL1	P00519	ABL1	Y393	R386Q	386	Missense	distal	-7	no	7.419	7.764	PhosphoSitePlus;EPSD	COSMIC	7.039	Up-regulation
TK_Abl_ABL1_Y	P00519	ABL1	P00519	ABL1	Y393	A397P	397	Missense	distal	4	no	7.419	7.280	PhosphoSitePlus;EPSD	COSMIC	7.039	Down-regulation
TK_Abl_ABL1_Y	P00519	ABL1	P00519	ABL1	Y393	H396R	396	Missense	distal	3	no	7.419	5.993	PhosphoSitePlus;EPSD	COSMIC	7.039	Loss
TK_Abl_ABL1_Y	P00519	ABL1	P00519	ABL1	Y393	L387M	387	Missense	distal	-6	no	7.419	7.431	PhosphoSitePlus;EPSD	COSMIC	7.039	Up-regulation
TK_Abl_ABL1_Y	P00519	ABL1	P00519	ABL1	Y393	M388L	388	Missense	distal	-5	no	7.419	6.896	PhosphoSitePlus;EPSD	COSMIC	7.039	Loss
TK_Abl_ABL1_Y	P00519	ABL1	P00519	ABL1	Y393	G398R	398	Missense	distal	5	no	7.419	7.066	PhosphoSitePlus;EPSD	COSMIC	7.039	Down-regulation
TK_Abl_ABL1_Y	P00519	ABL1	P00519	ABL1	Y393	A399T	399	Missense	distal	6	no	7.419	7.427	PhosphoSitePlus;EPSD	COSMIC	7.039	Up-regulation
TK_Abl_ABL1_Y	P00519	ABL1	P00519	ABL1	Y393	T389A	389	Missense	distal	-4	no	7.419	7.767	PhosphoSitePlus;EPSD	COSMIC	7.039	Up-regulation
TK_Abl_ABL1_Y	P00519	ABL1	P00519	ABL1	Y393	K400E	400	Missense	distal	7	no	7.419	7.387	PhosphoSitePlus;EPSD	COSMIC	7.039	Down-regulation
TK_Abl_ABL1_Y	P00519	ABL1	P00519	ABL1	Y393	T394A	394	Missense	proximal	1	no	7.419	8.685	PhosphoSitePlus;EPSD	COSMIC	7.039	Up-regulation
TK_Abl_ABL1_Y	P00519	ABL1	P00519	ABL1	Y393	H396P	396	Missense	distal	3	no	7.419	10.635	PhosphoSitePlus;EPSD	COSMIC	7.039	Up-regulation
TK_Abl_ABL1_Y	P00519	ABL1	P00519	ABL1	Y393	D391N	391	Missense	proximal	-2	no	7.419	8.015	PhosphoSitePlus;EPSD	COSMIC	7.039	Up-regulation
TK_Abl_ABL1_Y	P00519	ABL1	P00519	ABL1	Y393	L387F	387	Missense	distal	-6	no	7.419	7.389	PhosphoSitePlus;EPSD	COSMIC	7.039	Down-regulation
TK_Abl_ABL1_Y	P00519	ABL1	P00519	ABL1	Y393	H396Y	396	Missense	distal	3	no	7.419	6.997	PhosphoSitePlus;EPSD	COSMIC	7.039	Loss
TK_Abl_ABL1_Y	P00519	ABL1	P00519	ABL1	Y393	G390W	390	Missense	distal	-3	no	7.419	6.924	PhosphoSitePlus;EPSD	COSMIC	7.039	Loss
TK_Abl_ABL1_Y	O15350	TP73	P00519	ABL1	Y99	P102L	102	Missense	distal	3	no	11.076	8.498	PhosphoSitePlus	COSMIC	7.039	Down-regulation
TK_Abl_ABL1_Y	Q03135	CAV1	P00519	ABL1	Y14	H12Q	12	Missense	proximal	-2	no	13.796	14.435	PhosphoSitePlus	COSMIC	7.039	Up-regulation
TK_Abl_ABL1_Y	Q03135	CAV1	P00519	ABL1	Y14	Q21L	21	Missense	distal	7	no	13.796	13.751	PhosphoSitePlus	COSMIC	7.039	Down-regulation
TK_Abl_ABL1_Y	Q03135	CAV1	P00519	ABL1	Y14	L13H	13	Missense	proximal	-1	no	13.796	13.860	PhosphoSitePlus	COSMIC	7.039	Up-regulation
TK_Abl_ABL1_Y	Q03135	CAV1	P00519	ABL1	Y25	Q21L	21	Missense	distal	-4	no	7.852	6.860	EPSD	COSMIC	7.039	Loss
TK_Abl_ABL1_Y	Q06609	RAD51	P00519	ABL1	Y54	E50Q	50	Missense	distal	-4	no	7.756	6.270	EPSD;PhosphoSitePlus	COSMIC	7.039	Loss
TK_Abl_ABL1_Y	Q06609	RAD51	P00519	ABL1	Y54	V49L	49	Missense	distal	-5	no	7.756	6.392	EPSD;PhosphoSitePlus	COSMIC	7.039	Loss
TK_Abl_ABL1_Y	Q06609	RAD51	P00519	ABL1	Y54	A55V	55	Missense	proximal	1	no	7.756	6.738	EPSD;PhosphoSitePlus	COSMIC	7.039	Loss
TK_Abl_ABL1_Y	Q06609	RAD51	P00519	ABL1	Y315	C312S	312	Missense	distal	-3	no	14.055	14.121	PhosphoSitePlus;EPSD	COSMIC	7.039	Up-regulation
TK_Abl_ABL1_Y	Q06609	RAD51	P00519	ABL1	Y315	P318L	318	Missense	distal	3	no	14.055	11.477	PhosphoSitePlus;EPSD	COSMIC	7.039	Down-regulation
TK_Abl_ABL1_Y	Q06609	RAD51	P00519	ABL1	Y315	S317F	317	Missense	proximal	2	no	14.055	13.158	PhosphoSitePlus;EPSD	COSMIC	7.039	Down-regulation
TK_Abl_ABL1_Y	Q06609	RAD51	P00519	ABL1	Y315	C312Y	312	Missense	distal	-3	no	14.055	14.156	PhosphoSitePlus;EPSD	COSMIC	7.039	Up-regulation
TK_Abl_ABL1_Y	P55317	FOXA1	P00519	ABL1	Y459	L455M	455	Missense	distal	-4	no	7.548	7.924	EPSD	COSMIC	7.039	Up-regulation
TK_Abl_ABL1_Y	P55317	FOXA1	P00519	ABL1	Y459	P452A	452	Missense	distal	-7	no	7.548	7.578	EPSD	COSMIC	7.039	Up-regulation
TK_Abl_ABL1_Y	P55317	FOXA1	P00519	ABL1	Y459	G462A	462	Missense	distal	3	no	7.548	8.013	EPSD	COSMIC	7.039	Up-regulation
TK_Abl_ABL1_Y	P55317	FOXA1	P00519	ABL1	Y460	L455M	455	Missense	distal	-5	no	8.009	8.532	EPSD	COSMIC	7.039	Up-regulation
TK_Abl_ABL1_Y	P55317	FOXA1	P00519	ABL1	Y460	G462A	462	Missense	proximal	2	no	8.009	8.601	EPSD	COSMIC	7.039	Up-regulation
TK_Abl_ABL1_Y	P55317	FOXA1	P00519	ABL1	Y464	G462A	462	Missense	proximal	-2	no	11.533	11.198	PhosphoSitePlus;EPSD	COSMIC	7.039	Down-regulation
TK_Abl_ABL1_Y	P03372	ESR1	P00519	ABL1	Y52	S47T	47	Missense	distal	-5	no	9.828	10.150	PhosphoSitePlus;EPSD	COSMIC	7.039	Up-regulation
TK_Abl_ABL1_Y	P03372	ESR1	P00519	ABL1	Y52	Y54C	54	Missense	proximal	2	no	9.828	9.912	PhosphoSitePlus;EPSD	COSMIC	7.039	Up-regulation
TK_Abl_ABL1_Y	P03372	ESR1	P00519	ABL1	Y52	G57C	57	Missense	distal	5	no	9.828	10.024	PhosphoSitePlus;EPSD	COSMIC	7.039	Up-regulation
TK_Abl_ABL1_Y	P03372	ESR1	P00519	ABL1	Y52	A58T	58	Missense	distal	6	no	9.828	9.836	PhosphoSitePlus;EPSD	COSMIC	7.039	Up-regulation
TK_Abl_ABL1_Y	P03372	ESR1	P00519	ABL1	Y52	A50T	50	Missense	proximal	-2	no	9.828	10.044	PhosphoSitePlus;EPSD	COSMIC	7.039	Up-regulation
TK_Abl_ABL1_Y	P03372	ESR1	P00519	ABL1	Y52	K48N	48	Missense	distal	-4	no	9.828	11.585	PhosphoSitePlus;EPSD	COSMIC	7.039	Up-regulation
TK_Abl_ABL1_Y	P03372	ESR1	P00519	ABL1	Y52	G57S	57	Missense	distal	5	no	9.828	9.245	PhosphoSitePlus;EPSD	COSMIC	7.039	Down-regulation
TK_Abl_ABL1_Y	P03372	ESR1	P00519	ABL1	Y52	D45N	45	Missense	distal	-7	no	9.828	10.381	PhosphoSitePlus;EPSD	COSMIC	7.039	Up-regulation
TK_Abl_ABL1_Y	P03372	ESR1	P00519	ABL1	Y52	P49S	49	Missense	distal	-3	no	9.828	9.715	PhosphoSitePlus;EPSD	COSMIC	7.039	Down-regulation
TK_Abl_ABL1_Y	P03372	ESR1	P00519	ABL1	Y219	T224S	224	Missense	distal	5	no	9.788	10.019	EPSD;PhosphoSitePlus	COSMIC	7.039	Up-regulation
TK_Abl_ABL1_Y	P03372	ESR1	P00519	ABL1	Y219	M220T	220	Missense	proximal	1	no	9.788	9.632	EPSD;PhosphoSitePlus	COSMIC	7.039	Down-regulation
TK_Abl_ABL1_Y	P03372	ESR1	P00519	ABL1	Y219	Q214E	214	Missense	distal	-5	no	9.788	9.478	EPSD;PhosphoSitePlus	COSMIC	7.039	Down-regulation
TK_Abl_ABL1_Y	P03372	ESR1	P00519	ABL1	Y219	T224I	224	Missense	distal	5	no	9.788	10.417	EPSD;PhosphoSitePlus	COSMIC	7.039	Up-regulation
TK_Abl_ABL1_Y	P03372	ESR1	P00519	ABL1	Y219	I213N	213	Missense	distal	-6	no	9.788	9.873	EPSD;PhosphoSitePlus	COSMIC	7.039	Up-regulation
TK_Abl_ABL1_Y	P03372	ESR1	P00519	ABL1	Y328	P325L	325	Missense	distal	-3	no	7.495	6.728	EPSD	COSMIC	7.039	Loss
TK_Abl_ABL1_Y	P03372	ESR1	P00519	ABL1	Y328	D332V	332	Missense	distal	4	no	7.495	7.220	EPSD	COSMIC	7.039	Down-regulation
TK_Abl_ABL1_Y	P03372	ESR1	P00519	ABL1	Y328	S329Y	329	Missense	proximal	1	no	7.495	7.685	EPSD	COSMIC	7.039	Up-regulation
TK_Abl_ABL1_Y	P03372	ESR1	P00519	ABL1	Y328	P325S	325	Missense	distal	-3	no	7.495	7.383	EPSD	COSMIC	7.039	Down-regulation
TK_Abl_ABL1_Y	P03372	ESR1	P00519	ABL1	Y328	P333T	333	Missense	distal	5	no	7.495	7.263	EPSD	COSMIC	7.039	Down-regulation
TK_Abl_ABL1_Y	P03372	ESR1	P00519	ABL1	Y328	P324S	324	Missense	distal	-4	no	7.495	7.257	EPSD	COSMIC	7.039	Down-regulation
TK_Abl_ABL1_Y	Q13535	ATR	P00519	ABL1	Y291	D286N	286	Missense	distal	-5	no	7.178	6.945	EPSD;PhosphoSitePlus	COSMIC	7.039	Loss
TK_Abl_ABL1_Y	Q13535	ATR	P00519	ABL1	Y291	K297N	297	Missense	distal	6	no	7.178	7.278	EPSD;PhosphoSitePlus	COSMIC	7.039	Up-regulation
TK_Abl_ABL1_Y	Q13535	ATR	P00519	ABL1	Y310	V316I	316	Missense	distal	6	no	7.851	7.589	PhosphoSitePlus;EPSD	COSMIC	7.039	Down-regulation
TK_Abl_ABL1_Y	Q13535	ATR	P00519	ABL1	Y310	P304S	304	Missense	distal	-6	no	7.851	7.870	PhosphoSitePlus;EPSD	COSMIC	7.039	Up-regulation
TK_Abl_ABL1_Y	Q13535	ATR	P00519	ABL1	Y310	E306K	306	Missense	distal	-4	no	7.851	5.185	PhosphoSitePlus;EPSD	COSMIC	7.039	Loss
TK_Abl_ABL1_Y	Q13535	ATR	P00519	ABL1	Y310	E314K	314	Missense	distal	4	no	7.851	7.477	PhosphoSitePlus;EPSD	COSMIC	7.039	Down-regulation
TK_Abl_ABL1_Y	Q13535	ATR	P00519	ABL1	Y317	V316I	316	Missense	proximal	-1	no	6.409	8.175	EPSD	COSMIC	7.039	Gain
TK_Abl_ABL1_Y	Q13535	ATR	P00519	ABL1	Y1680	K1678N	1678	Missense	proximal	-2	no	6.856	7.663	EPSD	COSMIC	7.039	Gain
TK_Abl_ABL1_Y	Q13535	ATR	P00519	ABL1	Y1680	L1673V	1673	Missense	distal	-7	no	6.856	7.343	EPSD	COSMIC	7.039	Gain
TK_Abl_ABL1_Y	P11274	BCR	P00519	ABL1	Y283	I282M	282	Missense	proximal	-1	no	8.285	5.609	EPSD	COSMIC	7.039	Loss
TK_Abl_ABL1_Y	P11274	BCR	P00519	ABL1	Y283	E289G	289	Missense	distal	6	no	8.285	8.208	EPSD	COSMIC	7.039	Down-regulation
TK_Abl_ABL1_Y	P11274	BCR	P00519	ABL1	Y283	P278S	278	Missense	distal	-5	no	8.285	8.504	EPSD	COSMIC	7.039	Up-regulation
TK_Abl_ABL1_Y	P11274	BCR	P00519	ABL1	Y283	V284L	284	Missense	proximal	1	no	8.285	6.475	EPSD	COSMIC	7.039	Loss
TK_Abl_ABL1_Y	P11274	BCR	P00519	ABL1	Y360	R364Q	364	Missense	distal	4	no	9.495	8.941	EPSD	COSMIC	7.039	Down-regulation
TK_Abl_ABL1_Y	P11274	BCR	P00519	ABL1	Y360	M362I	362	Missense	proximal	2	no	9.495	9.929	EPSD	COSMIC	7.039	Up-regulation
TK_Abl_ABL1_Y	P11274	BCR	P00519	ABL1	Y455	P454S	454	Missense	proximal	-1	no	8.418	6.828	EPSD	COSMIC;CCLE	7.039	Loss
TK_Abl_ABL1_Y	P11274	BCR	P00519	ABL1	Y455	L453Q	453	Missense	proximal	-2	no	8.418	9.718	EPSD	COSMIC	7.039	Up-regulation
TK_Abl_ABL1_Y	P11274	BCR	P00519	ABL1	Y554	F560L	560	Missense	distal	6	no	7.654	7.068	EPSD	COSMIC	7.039	Down-regulation
TK_Abl_ABL1_Y	P11274	BCR	P00519	ABL1	Y554	E555K	555	Missense	proximal	1	no	7.654	7.114	EPSD	COSMIC	7.039	Down-regulation
TK_Abl_ABL1_Y	P19174	PLCG1	P00519	ABL1	Y162	F161L	161	Missense	proximal	-1	no	7.137	7.925	EPSD	COSMIC	7.039	Up-regulation
TK_Abl_ABL1_Y	P19174	PLCG1	P00519	ABL1	Y162	R166W	166	Missense	distal	4	no	7.137	6.488	EPSD	COSMIC	7.039	Loss
TK_Abl_ABL1_Y	P19174	PLCG1	P00519	ABL1	Y162	S163L	163	Missense	proximal	1	no	7.137	5.626	EPSD	COSMIC	7.039	Loss
TK_Abl_ABL1_Y	P19174	PLCG1	P00519	ABL1	Y162	R166Q	166	Missense	distal	4	no	7.137	6.584	EPSD	COSMIC	7.039	Loss
TK_Abl_ABL1_Y	P19174	PLCG1	P00519	ABL1	Y472	E473K	473	Missense	proximal	1	no	10.069	9.529	EPSD	COSMIC	7.039	Down-regulation
TK_Abl_ABL1_Y	P19174	PLCG1	P00519	ABL1	Y702	R707L	707	Missense	distal	5	no	6.754	7.156	EPSD	COSMIC	7.039	Gain
TK_Abl_ABL1_Y	P19174	PLCG1	P00519	ABL1	Y771	Y775F	775	Missense	distal	4	no	9.737	9.362	EPSD;PhosphoSitePlus	COSMIC	7.039	Down-regulation
TK_Abl_ABL1_Y	P19174	PLCG1	P00519	ABL1	Y977	P984L	984	Missense	distal	7	no	7.677	7.666	EPSD	COSMIC	7.039	Down-regulation
TK_Abl_ABL1_Y	P19174	PLCG1	P00519	ABL1	Y977	R978Q	978	Missense	proximal	1	no	7.677	7.943	EPSD	COSMIC	7.039	Up-regulation
TK_Abl_ABL1_Y	P19174	PLCG1	P00519	ABL1	Y1003	R1010C	1010	Missense	distal	7	no	7.294	7.212	PhosphoSitePlus;EPSD	COSMIC	7.039	Down-regulation
TK_Abl_ABL1_Y	P19174	PLCG1	P00519	ABL1	Y1003	G997S	997	Missense	distal	-6	no	7.294	7.441	PhosphoSitePlus;EPSD	COSMIC	7.039	Up-regulation
TK_Abl_ABL1_Y	P08581	MET	P00519	ABL1	Y84	K80N	80	Missense	distal	-4	no	5.714	7.472	EPSD	COSMIC	7.039	Gain
TK_Abl_ABL1_Y	P08581	MET	P00519	ABL1	Y291	S290F	290	Missense	proximal	-1	no	7.451	8.145	EPSD	COSMIC	7.039	Up-regulation
TK_Abl_ABL1_Y	P08581	MET	P00519	ABL1	Y291	I284M	284	Missense	distal	-7	no	7.451	7.921	EPSD	COSMIC	7.039	Up-regulation
TK_Abl_ABL1_Y	P08581	MET	P00519	ABL1	Y291	N285S	285	Missense	distal	-6	no	7.451	7.433	EPSD	COSMIC	7.039	Down-regulation
TK_Abl_ABL1_Y	P08581	MET	P00519	ABL1	Y745	P742A	742	Missense	distal	-3	no	8.513	8.829	EPSD	COSMIC	7.039	Up-regulation
TK_Abl_ABL1_Y	P08581	MET	P00519	ABL1	Y745	E740K	740	Missense	distal	-5	no	8.513	8.722	EPSD	COSMIC;GDSC;CCLE	7.039	Up-regulation
TK_Abl_ABL1_Y	P08581	MET	P00519	ABL1	Y745	E746G	746	Missense	proximal	1	no	8.513	8.073	EPSD	COSMIC	7.039	Down-regulation
TK_Abl_ABL1_Y	P08581	MET	P00519	ABL1	Y835	L833M	833	Missense	proximal	-2	no	8.252	8.311	EPSD	COSMIC	7.039	Up-regulation
TK_Abl_ABL1_Y	P08581	MET	P00519	ABL1	Y835	I834M	834	Missense	proximal	-1	no	8.252	5.576	EPSD	COSMIC	7.039	Loss
TK_Abl_ABL1_Y	P08581	MET	P00519	ABL1	Y835	D832H	832	Missense	distal	-3	no	8.252	7.400	EPSD	COSMIC	7.039	Down-regulation
TK_Abl_ABL1_Y	P08581	MET	P00519	ABL1	Y835	D832V	832	Missense	distal	-3	no	8.252	8.157	EPSD	COSMIC	7.039	Down-regulation
TK_Abl_ABL1_Y	P08581	MET	P00519	ABL1	Y835	P839L	839	Missense	distal	4	no	8.252	7.855	EPSD	COSMIC	7.039	Down-regulation
TK_Abl_ABL1_Y	P08581	MET	P00519	ABL1	Y1159	M1160L	1160	Missense	proximal	1	no	7.456	5.740	EPSD	COSMIC	7.039	Loss
TK_Abl_ABL1_Y	P08581	MET	P00519	ABL1	Y1159	D1164N	1164	Missense	distal	5	no	7.456	6.798	EPSD	COSMIC	7.039	Loss
TK_Abl_ABL1_Y	P08581	MET	P00519	ABL1	Y1159	H1162Y	1162	Missense	distal	3	no	7.456	7.035	EPSD	COSMIC	7.039	Loss
TK_Abl_ABL1_Y	P08581	MET	P00519	ABL1	Y1349	H1348N	1348	Missense	proximal	-1	no	7.534	6.857	EPSD;PhosphoSitePlus	COSMIC	7.039	Loss
TK_Abl_ABL1_Y	P08581	MET	P00519	ABL1	Y1349	A1354P	1354	Missense	distal	5	no	7.534	7.374	EPSD;PhosphoSitePlus	COSMIC	7.039	Down-regulation
TK_Abl_ABL1_Y	P08581	MET	P00519	ABL1	Y1349	G1346W	1346	Missense	distal	-3	no	7.534	7.039	EPSD;PhosphoSitePlus	COSMIC	7.039	Down-regulation
TK_Abl_ABL1_Y	P08581	MET	P00519	ABL1	Y1349	I1345T	1345	Missense	distal	-4	no	7.534	6.868	EPSD;PhosphoSitePlus	COSMIC	7.039	Loss
TK_Abl_ABL1_Y	P08581	MET	P00519	ABL1	Y1356	K1360E	1360	Missense	distal	4	no	6.978	7.352	PhosphoSitePlus;EPSD	COSMIC	7.039	Gain
TK_Abl_ABL1_Y	P08581	MET	P00519	ABL1	Y1356	A1354P	1354	Missense	proximal	-2	no	6.978	7.237	PhosphoSitePlus;EPSD	COSMIC	7.039	Gain
TK_Abl_ABL1_Y	Q06187	BTK	P00519	ABL1	Y551	L547Q	547	Missense	distal	-4	no	8.504	9.496	EPSD	COSMIC	7.039	Up-regulation
TK_Abl_ABL1_Y	Q06187	BTK	P00519	ABL1	Y551	R544W	544	Missense	distal	-7	no	8.504	7.918	EPSD	COSMIC	7.039	Down-regulation
TK_Abl_ABL1_Y	Q06187	BTK	P00519	ABL1	Y551	S553R	553	Missense	proximal	2	no	8.504	7.655	EPSD	COSMIC	7.039	Down-regulation
TK_Abl_ABL1_Y	Q06187	BTK	P00519	ABL1	Y551	R544M	544	Missense	distal	-7	no	8.504	8.686	EPSD	COSMIC	7.039	Up-regulation
TK_Abl_ABL1_Y	Q06187	BTK	P00519	ABL1	Y551	E550K	550	Missense	proximal	-1	no	8.504	6.810	EPSD	COSMIC	7.039	Loss
TK_Abl_ABL1_Y	Q6P1J9	CDC73	P00519	ABL1	Y293	E296K	296	Missense	distal	3	no	5.527	7.523	EPSD;PhosphoSitePlus	COSMIC	7.039	Gain
TK_Abl_ABL1_Y	Q6P1J9	CDC73	P00519	ABL1	Y315	D310G	310	Missense	distal	-5	no	7.368	7.338	PhosphoSitePlus;EPSD	COSMIC	7.039	Down-regulation
TK_Abl_ABL1_Y	Q6P1J9	CDC73	P00519	ABL1	Y315	D310A	310	Missense	distal	-5	no	7.368	7.619	PhosphoSitePlus;EPSD	COSMIC	7.039	Up-regulation
TK_Abl_ABL1_Y	Q6P1J9	CDC73	P00519	ABL1	Y315	S322C	322	Missense	distal	7	no	7.368	7.300	PhosphoSitePlus;EPSD	COSMIC	7.039	Down-regulation
TK_Abl_ABL1_Y	Q6P1J9	CDC73	P00519	ABL1	Y315	G313A	313	Missense	proximal	-2	no	7.368	7.034	PhosphoSitePlus;EPSD	COSMIC	7.039	Loss
TK_Abl_ABL1_Y	Q6P1J9	CDC73	P00519	ABL1	Y315	D310V	310	Missense	distal	-5	no	7.368	7.433	PhosphoSitePlus;EPSD	COSMIC	7.039	Up-regulation
TK_Abl_ABL1_Y	Q6P1J9	CDC73	P00519	ABL1	Y315	H316R	316	Missense	proximal	1	no	7.368	8.489	PhosphoSitePlus;EPSD	COSMIC	7.039	Up-regulation
TK_Abl_ABL1_Y	Q6P1J9	CDC73	P00519	ABL1	Y315	M312T	312	Missense	distal	-3	no	7.368	7.534	PhosphoSitePlus;EPSD	COSMIC	7.039	Up-regulation
TK_Abl_ABL1_Y	Q6P1J9	CDC73	P00519	ABL1	Y315	T311I	311	Missense	distal	-4	no	7.368	8.034	PhosphoSitePlus;EPSD	COSMIC	7.039	Up-regulation
TK_Abl_ABL1_Y	P00533	EGFR	P00519	ABL1	Y113	G109E	109	Missense	distal	-4	no	7.303	8.350	EPSD	COSMIC	7.039	Up-regulation
TK_Abl_ABL1_Y	P00533	EGFR	P00519	ABL1	Y113	A118V	118	Missense	distal	5	no	7.303	7.232	EPSD	COSMIC	7.039	Down-regulation
TK_Abl_ABL1_Y	P00533	EGFR	P00519	ABL1	Y113	N115T	115	Missense	proximal	2	no	7.303	7.293	EPSD	COSMIC	7.039	Down-regulation
TK_Abl_ABL1_Y	P00533	EGFR	P00519	ABL1	Y113	A118S	118	Missense	distal	5	no	7.303	7.142	EPSD	COSMIC	7.039	Down-regulation
TK_Abl_ABL1_Y	P00533	EGFR	P00519	ABL1	Y113	M111T	111	Missense	proximal	-2	no	7.303	7.786	EPSD	COSMIC	7.039	Up-regulation
TK_Abl_ABL1_Y	P00533	EGFR	P00519	ABL1	Y113	I106F	106	Missense	distal	-7	no	7.303	7.144	EPSD	COSMIC	7.039	Down-regulation
TK_Abl_ABL1_Y	P00533	EGFR	P00519	ABL1	Y113	E114G	114	Missense	proximal	1	no	7.303	6.862	EPSD	COSMIC	7.039	Loss
TK_Abl_ABL1_Y	P00533	EGFR	P00519	ABL1	Y113	L119S	119	Missense	distal	6	no	7.303	8.000	EPSD	COSMIC	7.039	Up-regulation
TK_Abl_ABL1_Y	P00533	EGFR	P00519	ABL1	Y113	A118T	118	Missense	distal	5	no	7.303	6.911	EPSD	COSMIC	7.039	Loss
TK_Abl_ABL1_Y	P00533	EGFR	P00519	ABL1	Y113	Y113H	113	Missense	central	0	yes	7.303	0.000	EPSD	COSMIC	7.039	Loss
TK_Abl_ABL1_Y	P00533	EGFR	P00519	ABL1	Y113	G109A	109	Missense	distal	-4	no	7.303	6.776	EPSD	COSMIC	7.039	Loss
TK_Abl_ABL1_Y	P00533	EGFR	P00519	ABL1	Y998	F997L	997	Missense	proximal	-1	no	7.230	8.017	EPSD	COSMIC	7.039	Up-regulation
TK_Abl_ABL1_Y	P00533	EGFR	P00519	ABL1	Y998	M1002V	1002	Missense	distal	4	no	7.230	7.406	EPSD	COSMIC	7.039	Up-regulation
TK_Abl_ABL1_Y	P00533	EGFR	P00519	ABL1	Y998	E1004K	1004	Missense	distal	6	no	7.230	7.591	EPSD	COSMIC	7.039	Up-regulation
TK_Abl_ABL1_Y	P00533	EGFR	P00519	ABL1	Y998	M1002I	1002	Missense	distal	4	no	7.230	7.612	EPSD	COSMIC	7.039	Up-regulation
TK_Abl_ABL1_Y	P00533	EGFR	P00519	ABL1	Y998	R999C	999	Missense	proximal	1	no	7.230	6.458	EPSD	COSMIC	7.039	Loss
TK_Abl_ABL1_Y	P00533	EGFR	P00519	ABL1	Y1016	P1019S	1019	Missense	distal	3	no	10.060	6.925	PhosphoSitePlus;EPSD	COSMIC	7.039	Loss
TK_Abl_ABL1_Y	P00533	EGFR	P00519	ABL1	Y1016	D1014G	1014	Missense	proximal	-2	no	10.060	10.453	PhosphoSitePlus;EPSD	COSMIC	7.039	Up-regulation
TK_Abl_ABL1_Y	P00533	EGFR	P00519	ABL1	Y1016	G1022S	1022	Missense	distal	6	no	10.060	10.304	PhosphoSitePlus;EPSD	COSMIC	7.039	Up-regulation
TK_Abl_ABL1_Y	P00533	EGFR	P00519	ABL1	Y1016	D1014V	1014	Missense	proximal	-2	no	10.060	10.578	PhosphoSitePlus;EPSD	COSMIC	7.039	Up-regulation
TK_Abl_ABL1_Y	P00533	EGFR	P00519	ABL1	Y1016	V1011E	1011	Missense	distal	-5	no	10.060	10.055	PhosphoSitePlus;EPSD	COSMIC	7.039	Down-regulation
TK_Abl_ABL1_Y	P00533	EGFR	P00519	ABL1	Y1016	D1014N	1014	Missense	proximal	-2	no	10.060	10.656	PhosphoSitePlus;EPSD	COSMIC	7.039	Up-regulation
TK_Abl_ABL1_Y	P00533	EGFR	P00519	ABL1	Y1016	V1010L	1010	Missense	distal	-6	no	10.060	9.976	PhosphoSitePlus;EPSD	COSMIC	7.039	Down-regulation
TK_Abl_ABL1_Y	P00533	EGFR	P00519	ABL1	Y1016	V1011M	1011	Missense	distal	-5	no	10.060	9.219	PhosphoSitePlus;EPSD	COSMIC;GDSC;CCLE	7.039	Down-regulation
TK_Abl_ABL1_Y	P00533	EGFR	P00519	ABL1	Y1016	D1012H	1012	Missense	distal	-4	no	10.060	9.471	PhosphoSitePlus;EPSD	COSMIC	7.039	Down-regulation
TK_Abl_ABL1_Y	P00533	EGFR	P00519	ABL1	Y1016	E1015K	1015	Missense	proximal	-1	no	10.060	8.366	PhosphoSitePlus;EPSD	COSMIC	7.039	Down-regulation
TK_Abl_ABL1_Y	P00533	EGFR	P00519	ABL1	Y1016	D1009Y	1009	Missense	distal	-7	no	10.060	9.672	PhosphoSitePlus;EPSD	COSMIC	7.039	Down-regulation
TK_Abl_ABL1_Y	P00533	EGFR	P00519	ABL1	Y1016	Q1020H	1020	Missense	distal	4	no	10.060	9.816	PhosphoSitePlus;EPSD	COSMIC	7.039	Down-regulation
TK_Abl_ABL1_Y	P00533	EGFR	P00519	ABL1	Y1016	V1010M	1010	Missense	distal	-6	no	10.060	9.988	PhosphoSitePlus;EPSD	COSMIC	7.039	Down-regulation
TK_Abl_ABL1_Y	P00533	EGFR	P00519	ABL1	Y1197	R1199M	1199	Missense	proximal	2	no	9.785	9.975	EPSD;PhosphoSitePlus	COSMIC	7.039	Up-regulation
TK_Abl_ABL1_Y	P00533	EGFR	P00519	ABL1	Y1197	S1204R	1204	Missense	distal	7	no	9.785	9.799	EPSD;PhosphoSitePlus	COSMIC	7.039	Up-regulation
TK_Abl_ABL1_Y	P00533	EGFR	P00519	ABL1	Y1197	A1201T	1201	Missense	distal	4	no	9.785	9.567	EPSD;PhosphoSitePlus	COSMIC	7.039	Down-regulation
TK_Abl_ABL1_Y	P00533	EGFR	P00519	ABL1	Y1197	R1199T	1199	Missense	proximal	2	no	9.785	10.243	EPSD;PhosphoSitePlus	COSMIC	7.039	Up-regulation
TK_Abl_ABL1_Y	P00533	EGFR	P00519	ABL1	Y1197	V1200I	1200	Missense	distal	3	no	9.785	8.268	EPSD;PhosphoSitePlus	COSMIC	7.039	Down-regulation
TK_Abl_ABL1_Y	P63244	RACK1	P00519	ABL1	Y52	L45I	45	Missense	distal	-7	no	8.118	8.066	PhosphoSitePlus	COSMIC	7.039	Down-regulation
TK_Abl_ABL1_Y	P63244	RACK1	P00519	ABL1	Y52	T50M	50	Missense	proximal	-2	no	8.118	7.635	PhosphoSitePlus	COSMIC	7.039	Down-regulation
TK_Abl_ABL1_Y	P63244	RACK1	P00519	ABL1	Y52	T50A	50	Missense	proximal	-2	no	8.118	7.902	PhosphoSitePlus	COSMIC	7.039	Down-regulation
TK_Abl_ABL1_Y	P63244	RACK1	P00519	ABL1	Y52	R57G	57	Missense	distal	5	no	8.118	8.471	PhosphoSitePlus	COSMIC	7.039	Up-regulation
TK_Abl_ABL1_Y	P63244	RACK1	P00519	ABL1	Y52	R47M	47	Missense	distal	-5	no	8.118	6.967	PhosphoSitePlus	COSMIC	7.039	Loss
TK_Abl_ABL1_Y	P63244	RACK1	P00519	ABL1	Y52	R57L	57	Missense	distal	5	no	8.118	8.521	PhosphoSitePlus	COSMIC	7.039	Up-regulation
TK_Abl_ABL1_Y	P63244	RACK1	P00519	ABL1	Y52	E49D	49	Missense	distal	-3	no	8.118	7.469	PhosphoSitePlus	COSMIC	7.039	Down-regulation
TK_Abl_ABL1_Y	P42684	ABL2	P00519	ABL1	Y261	T257K	257	Missense	distal	-4	no	8.150	7.406	PhosphoSitePlus	COSMIC	7.039	Down-regulation
TK_Abl_ABL1_Y	P42684	ABL2	P00519	ABL1	Y261	A263P	263	Missense	proximal	2	no	8.150	7.773	PhosphoSitePlus	COSMIC	7.039	Down-regulation
TK_Abl_ABL1_Y	P42684	ABL2	P00519	ABL1	Y261	P264L	264	Missense	distal	3	no	8.150	5.573	PhosphoSitePlus	COSMIC	7.039	Loss
TK_Abl_ABL1_Y	P42684	ABL2	P00519	ABL1	Y272	S275P	275	Missense	distal	3	no	8.028	11.163	EPSD	COSMIC	7.039	Up-regulation
TK_Abl_ABL1_Y	P42684	ABL2	P00519	ABL1	Y272	P276H	276	Missense	distal	4	no	8.028	7.232	EPSD	COSMIC	7.039	Down-regulation
TK_Abl_ABL1_Y	P42684	ABL2	P00519	ABL1	Y272	H278Y	278	Missense	distal	6	no	8.028	7.880	EPSD	COSMIC	7.039	Down-regulation
TK_Abl_ABL1_Y	P42684	ABL2	P00519	ABL1	Y272	D279N	279	Missense	distal	7	no	8.028	8.055	EPSD	COSMIC	7.039	Up-regulation
TK_Abl_ABL1_Y	P42684	ABL2	P00519	ABL1	Y299	Q298H	298	Missense	proximal	-1	no	5.939	7.157	EPSD	COSMIC	7.039	Gain
TK_Abl_ABL1_Y	P42684	ABL2	P00519	ABL1	Y366	Y363C	363	Missense	distal	-3	no	7.798	7.697	EPSD	COSMIC	7.039	Down-regulation
TK_Abl_ABL1_Y	P42684	ABL2	P00519	ABL1	Y366	Y372H	372	Missense	distal	6	no	7.798	7.946	EPSD	COSMIC	7.039	Up-regulation
TK_Abl_ABL1_Y	P42684	ABL2	P00519	ABL1	Y366	G367E	367	Missense	proximal	1	no	7.798	8.239	EPSD	COSMIC	7.039	Up-regulation
TK_Abl_ABL1_Y	P42684	ABL2	P00519	ABL1	Y366	G367R	367	Missense	proximal	1	no	7.798	7.737	EPSD	COSMIC	7.039	Down-regulation
TK_Abl_ABL1_Y	P42684	ABL2	P00519	ABL1	Y439	H442Y	442	Missense	distal	3	no	7.103	6.682	EPSD	COSMIC	7.039	Loss
TK_Abl_ABL1_Y	Q13188	STK3	P00519	ABL1	Y38	G39A	39	Missense	proximal	1	no	6.459	8.006	EPSD	COSMIC	7.039	Gain
TK_Abl_ABL1_Y	Q13188	STK3	P00519	ABL1	Y81	C77R	77	Missense	distal	-4	no	6.534	7.490	PhosphoSitePlus	COSMIC	7.039	Gain
TK_Abl_ABL1_Y	P53350	PLK1	P00519	ABL1	Y217	I218L	218	Missense	proximal	1	no	9.779	8.755	PhosphoSitePlus;EPSD	COSMIC	7.039	Down-regulation
TK_Abl_ABL1_Y	P53350	PLK1	P00519	ABL1	Y217	V222L	222	Missense	distal	5	no	9.779	10.322	PhosphoSitePlus;EPSD	COSMIC	7.039	Up-regulation
TK_Abl_ABL1_Y	P53350	PLK1	P00519	ABL1	Y445	G448V	448	Missense	distal	3	no	5.094	7.740	EPSD;PhosphoSitePlus	COSMIC	7.039	Gain
TK_Abl_ABL1_Y	Q13573	SNW1	P00519	ABL1	Y260	N256K	256	Missense	distal	-4	no	7.051	5.294	EPSD	COSMIC	7.039	Loss
TK_Abl_ABL1_Y	Q13573	SNW1	P00519	ABL1	Y292	A285T	285	Missense	distal	-7	no	7.093	7.439	PhosphoSitePlus;EPSD	COSMIC	7.039	Up-regulation
TK_Abl_ABL1_Y	Q13573	SNW1	P00519	ABL1	Y430	D434N	434	Missense	distal	4	no	7.489	7.531	EPSD;PhosphoSitePlus	COSMIC	7.039	Up-regulation
TK_Abl_ABL1_Y	Q13573	SNW1	P00519	ABL1	Y430	I429M	429	Missense	proximal	-1	no	7.489	4.813	EPSD;PhosphoSitePlus	COSMIC	7.039	Loss
TK_Abl_ABL1_Y	Q13573	SNW1	P00519	ABL1	Y430	D434G	434	Missense	distal	4	no	7.489	7.233	EPSD;PhosphoSitePlus	COSMIC	7.039	Down-regulation
TK_Abl_ABL1_Y	Q13573	SNW1	P00519	ABL1	Y433	D434N	434	Missense	proximal	1	no	8.545	8.245	EPSD;PhosphoSitePlus	COSMIC	7.039	Down-regulation
TK_Abl_ABL1_Y	Q13573	SNW1	P00519	ABL1	Y433	I429M	429	Missense	distal	-4	no	8.545	7.700	EPSD;PhosphoSitePlus	COSMIC	7.039	Down-regulation
TK_Abl_ABL1_Y	Q13573	SNW1	P00519	ABL1	Y433	D434G	434	Missense	proximal	1	no	8.545	7.673	EPSD;PhosphoSitePlus	COSMIC	7.039	Down-regulation
TK_Abl_ABL1_Y	Q6ZUJ8	PIK3AP1	P00519	ABL1	Y513	H514R	514	Missense	proximal	1	no	9.468	10.589	EPSD;PhosphoSitePlus	COSMIC	7.039	Up-regulation
TK_Abl_ABL1_Y	Q6ZUJ8	PIK3AP1	P00519	ABL1	Y553	E551K	551	Missense	proximal	-2	no	7.187	6.515	EPSD;PhosphoSitePlus	COSMIC;GDSC	7.039	Loss
TK_Abl_ABL1_Y	Q6ZUJ8	PIK3AP1	P00519	ABL1	Y553	P552Q	552	Missense	proximal	-1	no	7.187	5.925	EPSD;PhosphoSitePlus	COSMIC	7.039	Loss
TK_Abl_ABL1_Y	Q6ZUJ8	PIK3AP1	P00519	ABL1	Y553	D549Y	549	Missense	distal	-4	no	7.187	7.631	EPSD;PhosphoSitePlus	COSMIC	7.039	Up-regulation
TK_Abl_ABL1_Y	Q6ZUJ8	PIK3AP1	P00519	ABL1	Y553	P552S	552	Missense	proximal	-1	no	7.187	5.598	EPSD;PhosphoSitePlus	COSMIC	7.039	Loss
TK_Abl_ABL1_Y	Q6ZUJ8	PIK3AP1	P00519	ABL1	Y553	I554L	554	Missense	proximal	1	no	7.187	6.163	EPSD;PhosphoSitePlus	COSMIC	7.039	Loss
TK_Abl_ABL1_Y	Q6ZUJ8	PIK3AP1	P00519	ABL1	Y570	Q563K	563	Missense	distal	-7	no	10.002	9.773	PhosphoSitePlus;EPSD	COSMIC	7.039	Down-regulation
TK_Abl_ABL1_Y	Q6ZUJ8	PIK3AP1	P00519	ABL1	Y594	Y594C	594	Missense	central	0	yes	10.425	0.000	EPSD;PhosphoSitePlus	COSMIC	7.039	Loss
TK_Abl_ABL1_Y	Q6ZUJ8	PIK3AP1	P00519	ABL1	Y594	P589H	589	Missense	distal	-5	no	10.425	8.932	EPSD;PhosphoSitePlus	COSMIC	7.039	Down-regulation
TK_Abl_ABL1_Y	Q6ZUJ8	PIK3AP1	P00519	ABL1	Y694	S696T	696	Missense	proximal	2	no	9.720	9.329	EPSD;PhosphoSitePlus	COSMIC	7.039	Down-regulation
TK_Abl_ABL1_Y	Q6ZUJ8	PIK3AP1	P00519	ABL1	Y694	P698L	698	Missense	distal	4	no	9.720	9.323	EPSD;PhosphoSitePlus	COSMIC	7.039	Down-regulation
TK_Abl_ABL1_Y	Q6ZUJ8	PIK3AP1	P00519	ABL1	Y694	K688T	688	Missense	distal	-6	no	9.720	9.746	EPSD;PhosphoSitePlus	COSMIC	7.039	Up-regulation
TK_Abl_ABL1_Y	Q6ZUJ8	PIK3AP1	P00519	ABL1	Y694	S701N	701	Missense	distal	7	no	9.720	9.736	EPSD;PhosphoSitePlus	COSMIC	7.039	Up-regulation
TK_Abl_ABL1_Y	P17676	CEBPB	P00519	ABL1	Y137	G143V	143	Missense	distal	6	no	8.440	8.827	EPSD	COSMIC;CCLE	7.039	Up-regulation
TK_Abl_ABL1_Y	P01112	HRAS	P00519	ABL1	Y96	D92N	92	Missense	distal	-4	no	7.473	7.851	EPSD	COSMIC	7.039	Up-regulation
TK_Abl_ABL1_Y	P01112	HRAS	P00519	ABL1	Y96	R102Q	102	Missense	distal	6	no	7.473	8.327	EPSD	COSMIC	7.039	Up-regulation
TK_Abl_ABL1_Y	P01112	HRAS	P00519	ABL1	Y96	E91Q	91	Missense	distal	-5	no	7.473	7.783	EPSD	COSMIC	7.039	Up-regulation
TK_Abl_ABL1_Y	P01112	HRAS	P00519	ABL1	Y96	R102L	102	Missense	distal	6	no	7.473	6.913	EPSD	COSMIC	7.039	Loss
TK_Abl_ABL1_Y	P01112	HRAS	P00519	ABL1	Y96	S89T	89	Missense	distal	-7	no	7.473	7.771	EPSD	COSMIC	7.039	Up-regulation
TK_Abl_ABL1_Y	P01112	HRAS	P00519	ABL1	Y96	H94Y	94	Missense	proximal	-2	no	7.473	7.133	EPSD	COSMIC	7.039	Down-regulation
TK_Abl_ABL1_Y	P01112	HRAS	P00519	ABL1	Y137	A134S	134	Missense	distal	-3	no	7.057	6.630	PhosphoSitePlus	COSMIC;GDSC;CCLE	7.039	Loss
TK_Abl_ABL1_Y	P01112	HRAS	P00519	ABL1	Y137	Q131E	131	Missense	distal	-6	no	7.057	7.113	PhosphoSitePlus	COSMIC	7.039	Up-regulation
TK_Abl_ABL1_Y	P01112	HRAS	P00519	ABL1	Y137	L133R	133	Missense	distal	-4	no	7.057	8.290	PhosphoSitePlus	COSMIC;GDSC;CCLE	7.039	Up-regulation
TK_Abl_ABL1_Y	P01112	HRAS	P00519	ABL1	Y137	D132V	132	Missense	distal	-5	no	7.057	7.122	PhosphoSitePlus	COSMIC	7.039	Up-regulation
TK_Abl_ABL1_Y	P01112	HRAS	P00519	ABL1	Y137	Y137D	137	Missense	central	0	yes	7.057	0.000	PhosphoSitePlus	COSMIC	7.039	Loss
TK_Abl_ABL1_Y	P01112	HRAS	P00519	ABL1	Y137	T144I	144	Missense	distal	7	no	7.057	6.983	PhosphoSitePlus	COSMIC	7.039	Loss
TK_Abl_ABL1_Y	P01112	HRAS	P00519	ABL1	Y157	F156L	156	Missense	proximal	-1	no	6.254	7.041	EPSD	COSMIC	7.039	Gain
TK_Abl_ABL1_Y	O15151	MDM4	P00519	ABL1	Y55	G57D	57	Missense	proximal	2	no	9.089	9.154	PhosphoSitePlus;EPSD	COSMIC	7.039	Up-regulation
TK_Abl_ABL1_Y	O15151	MDM4	P00519	ABL1	Y55	H54Y	54	Missense	proximal	-1	no	9.089	9.735	PhosphoSitePlus;EPSD	COSMIC	7.039	Up-regulation
TK_Abl_ABL1_Y	O15151	MDM4	P00519	ABL1	Y99	L106F	106	Missense	distal	7	no	7.822	7.756	EPSD;PhosphoSitePlus	COSMIC	7.039	Down-regulation
TK_Abl_ABL1_Y	P09619	PDGFRB	P00519	ABL1	Y579	P584S	584	Missense	distal	5	no	7.429	7.428	EPSD	COSMIC	7.039	Down-regulation
TK_Abl_ABL1_Y	P09619	PDGFRB	P00519	ABL1	Y579	S574F	574	Missense	distal	-5	no	7.429	5.911	EPSD	COSMIC	7.039	Loss
TK_Abl_ABL1_Y	P09619	PDGFRB	P00519	ABL1	Y579	D583E	583	Missense	distal	4	no	7.429	7.556	EPSD	COSMIC	7.039	Up-regulation
TK_Abl_ABL1_Y	P09619	PDGFRB	P00519	ABL1	Y581	P584S	584	Missense	distal	3	no	8.600	5.465	EPSD	COSMIC	7.039	Loss
TK_Abl_ABL1_Y	P09619	PDGFRB	P00519	ABL1	Y581	S574F	574	Missense	distal	-7	no	8.600	8.120	EPSD	COSMIC	7.039	Down-regulation
TK_Abl_ABL1_Y	P09619	PDGFRB	P00519	ABL1	Y581	D583E	583	Missense	proximal	2	no	8.600	8.407	EPSD	COSMIC	7.039	Down-regulation
TK_Abl_ABL1_Y	P09619	PDGFRB	P00519	ABL1	Y589	E594K	594	Missense	distal	5	no	6.435	7.129	EPSD	COSMIC	7.039	Gain
TK_Abl_ABL1_Y	P09619	PDGFRB	P00519	ABL1	Y686	G687K	687	Missense	proximal	1	no	7.265	7.166	EPSD;PhosphoSitePlus	COSMIC	7.039	Down-regulation
TK_Abl_ABL1_Y	P09619	PDGFRB	P00519	ABL1	Y716	P710L	710	Missense	distal	-6	no	7.053	6.900	EPSD	COSMIC	7.039	Loss
TK_Abl_ABL1_Y	P09619	PDGFRB	P00519	ABL1	Y716	A713V	713	Missense	distal	-3	no	7.053	6.538	EPSD	COSMIC	7.039	Loss
TK_Abl_ABL1_Y	P09619	PDGFRB	P00519	ABL1	Y716	P711S	711	Missense	distal	-5	no	7.053	7.272	EPSD	COSMIC	7.039	Up-regulation
TK_Abl_ABL1_Y	P09619	PDGFRB	P00519	ABL1	Y716	R709H	709	Missense	distal	-7	no	7.053	6.854	EPSD	COSMIC	7.039	Loss
TK_Abl_ABL1_Y	P09619	PDGFRB	P00519	ABL1	Y716	A713T	713	Missense	distal	-3	no	7.053	6.390	EPSD	COSMIC;GDSC;CCLE	7.039	Loss
TK_Abl_ABL1_Y	P09619	PDGFRB	P00519	ABL1	Y751	D756N	756	Missense	distal	5	no	7.940	7.281	EPSD	COSMIC	7.039	Down-regulation
TK_Abl_ABL1_Y	P09619	PDGFRB	P00519	ABL1	Y751	M757I	757	Missense	distal	6	no	7.940	7.875	EPSD	COSMIC	7.039	Down-regulation
TK_Abl_ABL1_Y	P09619	PDGFRB	P00519	ABL1	Y751	P753T	753	Missense	proximal	2	no	7.940	8.124	EPSD	COSMIC;GDSC;CCLE	7.039	Up-regulation
TK_Abl_ABL1_Y	P09619	PDGFRB	P00519	ABL1	Y771	N770S	770	Missense	proximal	-1	no	8.867	7.998	EPSD	COSMIC	7.039	Down-regulation
TK_Abl_ABL1_Y	P09619	PDGFRB	P00519	ABL1	Y771	E767D	767	Missense	distal	-4	no	8.867	7.581	EPSD	COSMIC	7.039	Down-regulation
TK_Abl_ABL1_Y	P09619	PDGFRB	P00519	ABL1	Y771	M772I	772	Missense	proximal	1	no	8.867	8.174	EPSD	COSMIC;GDSC;CCLE	7.039	Down-regulation
TK_Abl_ABL1_Y	P09619	PDGFRB	P00519	ABL1	Y771	M772V	772	Missense	proximal	1	no	8.867	8.960	EPSD	COSMIC	7.039	Up-regulation
TK_Abl_ABL1_Y	P09619	PDGFRB	P00519	ABL1	Y934	E932K	932	Missense	proximal	-2	no	8.950	8.277	EPSD;PhosphoSitePlus	COSMIC	7.039	Down-regulation
TK_Abl_ABL1_Y	P09619	PDGFRB	P00519	ABL1	Y934	A929T	929	Missense	distal	-5	no	8.950	9.340	EPSD;PhosphoSitePlus	COSMIC	7.039	Up-regulation
TK_Abl_ABL1_Y	P09619	PDGFRB	P00519	ABL1	Y970	E964K	964	Missense	distal	-6	no	7.900	7.690	PhosphoSitePlus;EPSD	COSMIC;GDSC	7.039	Down-regulation
TK_Abl_ABL1_Y	P09619	PDGFRB	P00519	ABL1	Y970	G963D	963	Missense	distal	-7	no	7.900	8.157	PhosphoSitePlus;EPSD	COSMIC	7.039	Up-regulation
TK_Abl_ABL1_Y	P09619	PDGFRB	P00519	ABL1	Y970	K967Q	967	Missense	distal	-3	no	7.900	8.204	PhosphoSitePlus;EPSD	COSMIC	7.039	Up-regulation
TK_Abl_ABL1_Y	P09619	PDGFRB	P00519	ABL1	Y970	V973G	973	Missense	distal	3	no	7.900	5.253	PhosphoSitePlus;EPSD	COSMIC	7.039	Loss
TK_Abl_ABL1_Y	P09619	PDGFRB	P00519	ABL1	Y1009	S1006F	1006	Missense	distal	-3	no	8.739	7.316	EPSD	COSMIC	7.039	Down-regulation
TK_Abl_ABL1_Y	P09619	PDGFRB	P00519	ABL1	Y1009	L1002R	1002	Missense	distal	-7	no	8.739	8.976	EPSD	COSMIC	7.039	Up-regulation
TK_Abl_ABL1_Y	P09619	PDGFRB	P00519	ABL1	Y1009	A1011D	1011	Missense	proximal	2	no	8.739	8.212	EPSD	COSMIC	7.039	Down-regulation
TK_Abl_ABL1_Y	P09619	PDGFRB	P00519	ABL1	Y1009	Y1009S	1009	Missense	central	0	yes	8.739	0.000	EPSD	COSMIC	7.039	Loss
TK_Abl_ABL1_Y	P09619	PDGFRB	P00519	ABL1	Y1021	D1027N	1027	Missense	distal	6	no	7.377	7.982	EPSD	COSMIC	7.039	Up-regulation
TK_Abl_ABL1_Y	P09619	PDGFRB	P00519	ABL1	Y1021	D1018Y	1018	Missense	distal	-3	no	7.377	7.404	EPSD	COSMIC	7.039	Up-regulation
TK_Abl_ABL1_Y	P09619	PDGFRB	P00519	ABL1	Y1021	G1017D	1017	Missense	distal	-4	no	7.377	7.139	EPSD	COSMIC	7.039	Down-regulation
TK_Abl_ABL1_Y	Q92993	KAT5	P00519	ABL1	Y294	G297D	297	Missense	distal	3	no	11.601	12.395	PhosphoSitePlus;EPSD	COSMIC	7.039	Up-regulation
TK_Abl_ABL1_Y	Q92993	KAT5	P00519	ABL1	Y294	E292D	292	Missense	proximal	-2	no	11.601	11.139	PhosphoSitePlus;EPSD	COSMIC	7.039	Down-regulation
TK_Abl_ABL1_Y	Q92993	KAT5	P00519	ABL1	Y294	R295H	295	Missense	proximal	1	no	11.601	10.481	PhosphoSitePlus;EPSD	COSMIC	7.039	Down-regulation
TK_Abl_ABL1_Y	Q92993	KAT5	P00519	ABL1	Y294	S300F	300	Missense	distal	6	no	11.601	11.490	PhosphoSitePlus;EPSD	COSMIC	7.039	Down-regulation
TK_Abl_ABL1_Y	Q92993	KAT5	P00519	ABL1	Y294	E292K	292	Missense	proximal	-2	no	11.601	10.929	PhosphoSitePlus;EPSD	COSMIC	7.039	Down-regulation
TK_Abl_ABL1_Y	Q14247	CTTN	P00519	ABL1	Y538	G539V	539	Missense	proximal	1	no	8.489	9.018	EPSD	COSMIC	7.039	Up-regulation
TK_Abl_ABL1_Y	Q14247	CTTN	P00519	ABL1	Y538	V533L	533	Missense	distal	-5	no	8.489	7.125	EPSD	COSMIC;GDSC;CCLE	7.039	Down-regulation
TK_Abl_ABL1_Y	Q9H3D4	TP63	P00519	ABL1	Y149	P148L	148	Missense	proximal	-1	no	11.962	11.853	EPSD;PhosphoSitePlus	COSMIC	7.039	Down-regulation
TK_Abl_ABL1_Y	Q9H3D4	TP63	P00519	ABL1	Y149	T144A	144	Missense	distal	-5	no	11.962	11.571	EPSD;PhosphoSitePlus	COSMIC	7.039	Down-regulation
TK_Abl_ABL1_Y	Q9H3D4	TP63	P00519	ABL1	Y149	P146L	146	Missense	distal	-3	no	11.962	11.195	EPSD;PhosphoSitePlus	COSMIC	7.039	Down-regulation
TK_Abl_ABL1_Y	Q9H3D4	TP63	P00519	ABL1	Y149	Q151H	151	Missense	proximal	2	no	11.962	11.674	EPSD;PhosphoSitePlus	COSMIC	7.039	Down-regulation
TK_Abl_ABL1_Y	Q9H3D4	TP63	P00519	ABL1	Y149	S154C	154	Missense	distal	5	no	11.962	12.740	EPSD;PhosphoSitePlus	COSMIC;CCLE	7.039	Up-regulation
TK_Abl_ABL1_Y	Q9H3D4	TP63	P00519	ABL1	Y149	S153I	153	Missense	distal	4	no	11.962	12.146	EPSD;PhosphoSitePlus	COSMIC	7.039	Up-regulation
TK_Abl_ABL1_Y	Q9H3D4	TP63	P00519	ABL1	Y149	S147W	147	Missense	proximal	-2	no	11.962	10.228	EPSD;PhosphoSitePlus	COSMIC	7.039	Down-regulation
TK_Abl_ABL1_Y	Q9H3D4	TP63	P00519	ABL1	Y149	P148H	148	Missense	proximal	-1	no	11.962	11.917	EPSD;PhosphoSitePlus	COSMIC	7.039	Down-regulation
TK_Abl_ABL1_Y	Q9H3D4	TP63	P00519	ABL1	Y290	P293F	293	Missense	distal	3	no	8.252	6.342	EPSD;PhosphoSitePlus	COSMIC	7.039	Loss
TK_Abl_ABL1_Y	Q9H3D4	TP63	P00519	ABL1	Y290	Y290F	290	Missense	central	0	yes	8.252	0.000	EPSD;PhosphoSitePlus	COSMIC	7.039	Loss
TK_Abl_ABL1_Y	Q9H3D4	TP63	P00519	ABL1	Y290	S285R	285	Missense	distal	-5	no	8.252	8.308	EPSD;PhosphoSitePlus	COSMIC	7.039	Up-regulation
TK_Abl_ABL1_Y	Q9Y6Q9	NCOA3	P00519	ABL1	Y1357	M1362K	1362	Missense	distal	5	no	8.959	9.706	PhosphoSitePlus	COSMIC	7.039	Up-regulation
TK_Abl_ABL1_Y	Q9Y6Q9	NCOA3	P00519	ABL1	Y1357	S1359P	1359	Missense	proximal	2	no	8.959	8.384	PhosphoSitePlus	COSMIC	7.039	Down-regulation
TK_Abl_ABL1_Y	Q9Y6Q9	NCOA3	P00519	ABL1	Y1357	S1355P	1355	Missense	proximal	-2	no	8.959	8.567	PhosphoSitePlus	COSMIC	7.039	Down-regulation
TK_Abl_ABL1_Y	P46108	CRK	P00519	ABL1	Y221	P216S	216	Missense	distal	-5	no	16.217	16.436	PhosphoSitePlus;EPSD	COSMIC	7.039	Up-regulation
TK_Abl_ABL1_Y	P46108	CRK	P00519	ABL1	Y239	N235D	235	Missense	distal	-4	no	10.694	10.317	EPSD;PhosphoSitePlus	COSMIC	7.039	Down-regulation
TK_Abl_ABL1_Y	P46108	CRK	P00519	ABL1	Y251	D252A	252	Missense	proximal	1	no	7.211	7.886	EPSD;PhosphoSitePlus	COSMIC	7.039	Up-regulation
TK_Abl_ABL1_Y	Q14498	RBM39	P00519	ABL1	Y95	Y95D	95	Missense	central	0	yes	8.709	0.000	PhosphoSitePlus;EPSD	COSMIC	7.039	Loss
TK_Abl_ABL1_Y	Q14498	RBM39	P00519	ABL1	Y95	R94C	94	Missense	proximal	-1	no	8.709	10.663	PhosphoSitePlus;EPSD	COSMIC	7.039	Up-regulation
TK_Abl_ABL1_Y	Q14498	RBM39	P00519	ABL1	Y95	R89Q	89	Missense	distal	-6	no	8.709	8.646	PhosphoSitePlus;EPSD	COSMIC	7.039	Down-regulation
TK_Abl_ABL1_Y	Q14498	RBM39	P00519	ABL1	Y95	P98L	98	Missense	distal	3	no	8.709	6.131	PhosphoSitePlus;EPSD	COSMIC	7.039	Loss
TK_Abl_ABL1_Y	Q14498	RBM39	P00519	ABL1	Y95	G101E	101	Missense	distal	6	no	8.709	8.786	PhosphoSitePlus;EPSD	COSMIC;GDSC;CCLE	7.039	Up-regulation
TK_Abl_ABL1_Y	Q14498	RBM39	P00519	ABL1	Y99	Y95D	95	Missense	distal	-4	no	11.761	11.317	EPSD;PhosphoSitePlus	COSMIC	7.039	Down-regulation
TK_Abl_ABL1_Y	Q14498	RBM39	P00519	ABL1	Y99	R94C	94	Missense	distal	-5	no	11.761	9.704	EPSD;PhosphoSitePlus	COSMIC	7.039	Down-regulation
TK_Abl_ABL1_Y	Q14498	RBM39	P00519	ABL1	Y99	P98L	98	Missense	proximal	-1	no	11.761	11.652	EPSD;PhosphoSitePlus	COSMIC	7.039	Down-regulation
TK_Abl_ABL1_Y	Q14498	RBM39	P00519	ABL1	Y99	G101E	101	Missense	proximal	2	no	11.761	11.633	EPSD;PhosphoSitePlus	COSMIC;GDSC;CCLE	7.039	Down-regulation
TK_Abl_ABL1_Y	Q14498	RBM39	P00519	ABL1	Y253	P249S	249	Missense	distal	-4	no	7.844	7.606	EPSD	COSMIC	7.039	Down-regulation
TK_Abl_ABL1_Y	Q14498	RBM39	P00519	ABL1	Y253	F259L	259	Missense	distal	6	no	7.844	7.257	EPSD	COSMIC	7.039	Down-regulation
TK_Abl_ABL1_Y	Q14498	RBM39	P00519	ABL1	Y253	A247V	247	Missense	distal	-6	no	7.844	7.865	EPSD	COSMIC	7.039	Up-regulation
TK_Abl_ABL1_Y	Q14498	RBM39	P00519	ABL1	Y253	V254L	254	Missense	proximal	1	no	7.844	6.034	EPSD	COSMIC	7.039	Loss
TK_Abl_ABL1_Y	Q14498	RBM39	P00519	ABL1	Y253	S256G	256	Missense	distal	3	no	7.844	6.411	EPSD	COSMIC	7.039	Loss
TK_Abl_ABL1_Y	Q14498	RBM39	P00519	ABL1	Y505	V506A	506	Missense	proximal	1	no	6.925	7.942	EPSD	COSMIC;CCLE	7.039	Gain
TK_Abl_ABL1_Y	Q14498	RBM39	P00519	ABL1	Y505	G498S	498	Missense	distal	-7	no	6.925	7.067	EPSD	COSMIC	7.039	Gain
TK_Abl_ABL1_Y	Q14498	RBM39	P00519	ABL1	Y505	P509A	509	Missense	distal	4	no	6.925	7.064	EPSD	COSMIC	7.039	Gain
TK_Abl_ABL1_Y	Q14498	RBM39	P00519	ABL1	Y505	G498D	498	Missense	distal	-7	no	6.925	7.182	EPSD	COSMIC	7.039	Gain
TK_Abl_ABL1_Y	P55211	CASP9	P00519	ABL1	Y397	G395V	395	Missense	proximal	-2	no	9.559	9.684	EPSD;PhosphoSitePlus	COSMIC	7.039	Up-regulation
TK_Abl_ABL1_Y	P55211	CASP9	P00519	ABL1	Y397	G402D	402	Missense	distal	5	no	9.559	9.208	EPSD;PhosphoSitePlus	COSMIC	7.039	Down-regulation
TK_Abl_ABL1_Y	P50402	EMD	P00519	ABL1	Y105	R103S	103	Missense	proximal	-2	no	7.479	8.247	EPSD	COSMIC	7.039	Up-regulation
TK_Abl_ABL1_Y	P50402	EMD	P00519	ABL1	Y155	R150M	150	Missense	distal	-5	no	8.230	7.079	EPSD	COSMIC	7.039	Down-regulation
TK_Abl_ABL1_Y	P50402	EMD	P00519	ABL1	Y155	R152C	152	Missense	distal	-3	no	8.230	8.214	EPSD	COSMIC	7.039	Down-regulation
TK_Abl_ABL1_Y	P50402	EMD	P00519	ABL1	Y167	R174K	174	Missense	distal	7	no	7.905	7.900	PhosphoSitePlus	COSMIC	7.039	Down-regulation
TK_Abl_ABL1_Y	P50402	EMD	P00519	ABL1	Y167	H166Y	166	Missense	proximal	-1	no	7.905	8.551	PhosphoSitePlus	COSMIC	7.039	Up-regulation
TK_Abl_ABL1_Y	P16333	NCK1	P00519	ABL1	Y105	Y112F	112	Missense	distal	7	no	9.116	9.084	PhosphoSitePlus	COSMIC;GDSC;CCLE	7.039	Down-regulation
TK_Abl_ABL1_Y	P16333	NCK1	P00519	ABL1	Y105	V98A	98	Missense	distal	-7	no	9.116	8.849	PhosphoSitePlus	COSMIC	7.039	Down-regulation
TK_Abl_ABL1_Y	P16333	NCK1	P00519	ABL1	Y105	R103C	103	Missense	proximal	-2	no	9.116	8.931	PhosphoSitePlus	COSMIC	7.039	Down-regulation
TK_Abl_ABL1_Y	P16333	NCK1	P00519	ABL1	Y246	Q251R	251	Missense	distal	5	no	6.684	7.144	EPSD	COSMIC	7.039	Gain
TK_Abl_ABL1_Y	P16333	NCK1	P00519	ABL1	Y246	K244E	244	Missense	proximal	-2	no	6.684	7.356	EPSD	COSMIC	7.039	Gain
TK_Abl_ABL1_Y	O15162	PLSCR1	P00519	ABL1	Y69	N70S	70	Missense	proximal	1	no	10.711	10.370	PhosphoSitePlus;EPSD	COSMIC	7.039	Down-regulation
TK_Abl_ABL1_Y	O15162	PLSCR1	P00519	ABL1	Y74	N70S	70	Missense	distal	-4	no	9.875	9.259	EPSD;PhosphoSitePlus	COSMIC	7.039	Down-regulation
TK_Abl_ABL1_Y	P43351	RAD52	P00519	ABL1	Y104	N99D	99	Missense	distal	-5	no	8.111	8.345	PhosphoSitePlus	COSMIC	7.039	Up-regulation
TK_Abl_ABL1_Y	P43351	RAD52	P00519	ABL1	Y205	P210L	210	Missense	distal	5	no	10.511	11.143	EPSD	COSMIC	7.039	Up-regulation
TK_Abl_ABL1_Y	P43351	RAD52	P00519	ABL1	Y205	C208R	208	Missense	distal	3	no	10.511	9.604	EPSD	COSMIC	7.039	Down-regulation
TK_Abl_ABL1_Y	Q9Y6N7	ROBO1	P00519	ABL1	Y1038	P1033L	1033	Missense	distal	-5	no	10.246	8.847	EPSD;PhosphoSitePlus	COSMIC	7.039	Down-regulation
TK_Abl_ABL1_Y	Q9Y6N7	ROBO1	P00519	ABL1	Y1038	Y1038H	1038	Missense	central	0	yes	10.246	0.000	EPSD;PhosphoSitePlus	COSMIC	7.039	Loss
TK_Abl_ABL1_Y	Q9Y6N7	ROBO1	P00519	ABL1	Y1038	P1033S	1033	Missense	distal	-5	no	10.246	10.465	EPSD;PhosphoSitePlus	COSMIC	7.039	Up-regulation
TK_Abl_ABL1_Y	Q9Y6N7	ROBO1	P00519	ABL1	Y1038	Y1038S	1038	Missense	central	0	yes	10.246	0.000	EPSD;PhosphoSitePlus	COSMIC	7.039	Loss
TK_Abl_ABL1_Y	Q9Y6N7	ROBO1	P00519	ABL1	Y1038	L1043I	1043	Missense	distal	5	no	10.246	10.013	EPSD;PhosphoSitePlus	COSMIC	7.039	Down-regulation
TK_Abl_ABL1_Y	Q9Y6N7	ROBO1	P00519	ABL1	Y1114	K1121R	1121	Missense	distal	7	no	8.926	8.931	PhosphoSitePlus;EPSD	COSMIC	7.039	Up-regulation
TK_Abl_ABL1_Y	Q9Y6N7	ROBO1	P00519	ABL1	Y1114	K1121N	1121	Missense	distal	7	no	8.926	8.932	PhosphoSitePlus;EPSD	COSMIC	7.039	Up-regulation
TK_Abl_ABL1_Y	Q9Y6N7	ROBO1	P00519	ABL1	Y1114	Q1113H	1113	Missense	proximal	-1	no	8.926	10.144	PhosphoSitePlus;EPSD	COSMIC	7.039	Up-regulation
TK_Abl_ABL1_Y	Q9Y6N7	ROBO1	P00519	ABL1	Y1150	S1149F	1149	Missense	proximal	-1	no	6.480	7.175	EPSD	COSMIC	7.039	Gain
TK_Abl_ABL1_Y	Q9Y6N7	ROBO1	P00519	ABL1	Y1150	S1149P	1149	Missense	proximal	-1	no	6.480	8.070	EPSD	COSMIC	7.039	Gain
TK_Abl_ABL1_Y	Q9Y6N7	ROBO1	P00519	ABL1	Y1587	F1592L	1592	Missense	distal	5	no	8.352	8.267	EPSD	COSMIC	7.039	Down-regulation
TK_Abl_ABL1_Y	Q9Y6N7	ROBO1	P00519	ABL1	Y1587	E1582D	1582	Missense	distal	-5	no	8.352	8.293	EPSD	COSMIC	7.039	Down-regulation
TK_Abl_ABL1_Y	Q9Y6N7	ROBO1	P00519	ABL1	Y1587	T1591N	1591	Missense	distal	4	no	8.352	8.445	EPSD	COSMIC	7.039	Up-regulation
TK_Abl_ABL1_Y	Q9Y6N7	ROBO1	P00519	ABL1	Y1587	P1593T	1593	Missense	distal	6	no	8.352	8.283	EPSD	COSMIC	7.039	Down-regulation
TK_Abl_ABL1_Y	P04083	ANXA1	P00519	ABL1	Y207	E208K	208	Missense	proximal	1	no	7.140	6.600	EPSD	COSMIC	7.039	Loss
TK_Abl_ABL1_Y	P49023	PXN	P00519	ABL1	Y31	P30L	30	Missense	proximal	-1	no	13.462	13.354	EPSD;PhosphoSitePlus	COSMIC	7.039	Down-regulation
TK_Abl_ABL1_Y	P49023	PXN	P00519	ABL1	Y118	F120S	120	Missense	proximal	2	no	10.240	11.137	PhosphoSitePlus;EPSD	COSMIC	7.039	Up-regulation
TK_Abl_ABL1_Y	P49023	PXN	P00519	ABL1	Y181	G175W	175	Missense	distal	-6	no	7.226	7.217	EPSD	COSMIC	7.039	Down-regulation
TK_Abl_ABL1_Y	P49023	PXN	P00519	ABL1	Y404	F397L	397	Missense	distal	-7	no	7.343	7.554	EPSD	COSMIC	7.039	Up-regulation
TK_Abl_ABL1_Y	P49023	PXN	P00519	ABL1	Y404	K407E	407	Missense	distal	3	no	7.343	5.347	EPSD	COSMIC	7.039	Loss
TK_Abl_ABL1_Y	P49023	PXN	P00519	ABL1	Y404	R399Q	399	Missense	distal	-5	no	7.343	7.337	EPSD	COSMIC	7.039	Down-regulation
TK_Abl_ABL1_Y	P49023	PXN	P00519	ABL1	Y404	R399W	399	Missense	distal	-5	no	7.343	4.810	EPSD	COSMIC	7.039	Loss
TK_Abl_ABL1_Y	P46109	CRKL	P00519	ABL1	Y15	M16I	16	Missense	proximal	1	no	7.956	7.264	EPSD	COSMIC	7.039	Down-regulation
TK_Abl_ABL1_Y	P46109	CRKL	P00519	ABL1	Y15	P18L	18	Missense	distal	3	no	7.956	5.379	EPSD	COSMIC;GDSC;CCLE	7.039	Loss
TK_Abl_ABL1_Y	P46109	CRKL	P00519	ABL1	Y15	A13T	13	Missense	proximal	-2	no	7.956	8.173	EPSD	COSMIC;CCLE	7.039	Up-regulation
TK_Abl_ABL1_Y	P46109	CRKL	P00519	ABL1	Y61	P67L	67	Missense	distal	6	no	8.719	8.050	EPSD	COSMIC	7.039	Down-regulation
TK_Abl_ABL1_Y	P46109	CRKL	P00519	ABL1	Y105	S112C	112	Missense	distal	7	no	7.660	7.591	EPSD	COSMIC	7.039	Down-regulation
TK_Abl_ABL1_Y	P46109	CRKL	P00519	ABL1	Y132	V128I	128	Missense	distal	-4	no	8.338	8.433	EPSD	COSMIC	7.039	Up-regulation
TK_Abl_ABL1_Y	P46109	CRKL	P00519	ABL1	Y132	T130A	130	Missense	proximal	-2	no	8.338	8.121	EPSD	COSMIC	7.039	Down-regulation
TK_Abl_ABL1_Y	P46109	CRKL	P00519	ABL1	Y132	R129Q	129	Missense	distal	-3	no	8.338	8.322	EPSD	COSMIC	7.039	Down-regulation
TK_Abl_ABL1_Y	P46109	CRKL	P00519	ABL1	Y132	G136E	136	Missense	distal	4	no	8.338	8.721	EPSD	COSMIC	7.039	Up-regulation
TK_Abl_ABL1_Y	P46109	CRKL	P00519	ABL1	Y132	G136W	136	Missense	distal	4	no	8.338	7.974	EPSD	COSMIC	7.039	Down-regulation
TK_Abl_ABL1_Y	P46109	CRKL	P00519	ABL1	Y177	P176S	176	Missense	proximal	-1	no	7.588	5.998	EPSD	COSMIC	7.039	Loss
TK_Abl_ABL1_Y	P46109	CRKL	P00519	ABL1	Y177	M172V	172	Missense	distal	-5	no	7.588	8.428	EPSD	COSMIC	7.039	Up-regulation
TK_Abl_ABL1_Y	P46109	CRKL	P00519	ABL1	Y177	E179K	179	Missense	proximal	2	no	7.588	7.605	EPSD	COSMIC	7.039	Up-regulation
TK_Abl_ABL1_Y	P46109	CRKL	P00519	ABL1	Y177	Y177C	177	Missense	central	0	yes	7.588	0.000	EPSD	COSMIC	7.039	Loss
TK_Abl_ABL1_Y	P46109	CRKL	P00519	ABL1	Y198	P201L	201	Missense	distal	3	no	9.597	7.020	EPSD	COSMIC	7.039	Loss
TK_Abl_ABL1_Y	P46109	CRKL	P00519	ABL1	Y198	Y198C	198	Missense	central	0	yes	9.597	0.000	EPSD	COSMIC	7.039	Loss
TK_Abl_ABL1_Y	P46109	CRKL	P00519	ABL1	Y198	S197N	197	Missense	proximal	-1	no	9.597	10.465	EPSD	COSMIC	7.039	Up-regulation
TK_Abl_ABL1_Y	P46109	CRKL	P00519	ABL1	Y198	I200T	200	Missense	proximal	2	no	9.597	9.431	EPSD	COSMIC	7.039	Down-regulation
TK_Abl_ABL1_Y	P46109	CRKL	P00519	ABL1	Y207	P201L	201	Missense	distal	-6	no	8.825	8.672	PhosphoSitePlus	COSMIC	7.039	Down-regulation
TK_Abl_ABL1_Y	P46109	CRKL	P00519	ABL1	Y207	I200T	200	Missense	distal	-7	no	8.825	9.443	PhosphoSitePlus	COSMIC	7.039	Up-regulation
TK_Abl_ABL1_Y	P15498	VAV1	P00519	ABL1	Y142	D138N	138	Missense	distal	-4	no	10.363	10.740	EPSD	COSMIC	7.039	Up-regulation
TK_Abl_ABL1_Y	P15498	VAV1	P00519	ABL1	Y160	E157K	157	Missense	distal	-3	no	7.926	6.900	EPSD	COSMIC	7.039	Loss
TK_Abl_ABL1_Y	P15498	VAV1	P00519	ABL1	Y174	E175V	175	Missense	proximal	1	no	10.850	10.939	PhosphoSitePlus;EPSD	COSMIC	7.039	Up-regulation
TK_Abl_ABL1_Y	P15498	VAV1	P00519	ABL1	Y174	Y174C	174	Missense	central	0	yes	10.850	0.000	PhosphoSitePlus;EPSD	COSMIC	7.039	Loss
TK_Abl_ABL1_Y	P15498	VAV1	P00519	ABL1	Y174	E175L	175	Missense	proximal	1	no	10.850	9.129	PhosphoSitePlus;EPSD	COSMIC	7.039	Down-regulation
TK_Abl_ABL1_Y	P15498	VAV1	P00519	ABL1	Y174	M178R	178	Missense	distal	4	no	10.850	11.331	PhosphoSitePlus;EPSD	COSMIC	7.039	Up-regulation
TK_Abl_ABL1_Y	P15498	VAV1	P00519	ABL1	Y174	L177R	177	Missense	distal	3	no	10.850	8.786	PhosphoSitePlus;EPSD	COSMIC	7.039	Down-regulation
TK_Abl_ABL1_Y	P15498	VAV1	P00519	ABL1	Y174	D176N	176	Missense	proximal	2	no	10.850	11.193	PhosphoSitePlus;EPSD	COSMIC	7.039	Up-regulation
TK_Abl_ABL1_Y	P15498	VAV1	P00519	ABL1	Y267	A264T	264	Missense	distal	-3	no	9.143	8.481	EPSD;PhosphoSitePlus	COSMIC	7.039	Down-regulation
TK_Abl_ABL1_Y	P15498	VAV1	P00519	ABL1	Y267	L266P	266	Missense	proximal	-1	no	9.143	9.252	EPSD;PhosphoSitePlus	COSMIC	7.039	Up-regulation
TK_Abl_ABL1_Y	P15498	VAV1	P00519	ABL1	Y267	L266M	266	Missense	proximal	-1	no	9.143	7.926	EPSD;PhosphoSitePlus	COSMIC	7.039	Down-regulation
TK_Abl_ABL1_Y	P15498	VAV1	P00519	ABL1	Y267	G262E	262	Missense	distal	-5	no	9.143	9.233	EPSD;PhosphoSitePlus	COSMIC	7.039	Up-regulation
TK_Abl_ABL1_Y	P15498	VAV1	P00519	ABL1	Y841	E839K	839	Missense	proximal	-2	no	8.589	7.916	EPSD	COSMIC	7.039	Down-regulation
TK_Abl_ABL1_Y	P15498	VAV1	P00519	ABL1	Y841	E838K	838	Missense	distal	-3	no	8.589	7.562	EPSD	COSMIC	7.039	Down-regulation
TK_Abl_ABL1_Y	P15498	VAV1	P00519	ABL1	Y844	E839K	839	Missense	distal	-5	no	7.917	8.125	EPSD	COSMIC	7.039	Up-regulation
TK_Abl_ABL1_Y	P15498	VAV1	P00519	ABL1	Y844	E838K	838	Missense	distal	-6	no	7.917	7.707	EPSD	COSMIC	7.039	Down-regulation
TK_Abl_ABL1_Y	Q9UPY6	WASF3	P00519	ABL1	Y151	D146Y	146	Missense	distal	-5	no	11.116	10.435	EPSD;PhosphoSitePlus	COSMIC	7.039	Down-regulation
TK_Abl_ABL1_Y	Q9UPY6	WASF3	P00519	ABL1	Y151	S155F	155	Missense	distal	4	no	11.116	10.814	EPSD;PhosphoSitePlus	COSMIC	7.039	Down-regulation
TK_Abl_ABL1_Y	Q9UPY6	WASF3	P00519	ABL1	Y151	T152S	152	Missense	proximal	1	no	11.116	11.066	EPSD;PhosphoSitePlus	COSMIC	7.039	Down-regulation
TK_Abl_ABL1_Y	Q9UPY6	WASF3	P00519	ABL1	Y248	P251S	251	Missense	distal	3	no	11.586	8.451	EPSD;PhosphoSitePlus	COSMIC	7.039	Down-regulation
TK_Abl_ABL1_Y	Q9UPY6	WASF3	P00519	ABL1	Y248	S243L	243	Missense	distal	-5	no	11.586	9.968	EPSD;PhosphoSitePlus	COSMIC	7.039	Down-regulation
TK_Abl_ABL1_Y	Q9UPY6	WASF3	P00519	ABL1	Y286	E285K	285	Missense	proximal	-1	no	8.322	6.627	EPSD	COSMIC	7.039	Loss
TK_Abl_ABL1_Y	Q9UPY6	WASF3	P00519	ABL1	Y286	Y286C	286	Missense	central	0	yes	8.322	0.000	EPSD	COSMIC;CCLE	7.039	Loss
TK_Abl_ABL1_Y	Q9UPY6	WASF3	P00519	ABL1	Y286	R287Q	287	Missense	proximal	1	no	8.322	8.588	EPSD	COSMIC	7.039	Up-regulation
TK_Abl_ABL1_Y	Q9UPY6	WASF3	P00519	ABL1	Y337	P343L	343	Missense	distal	6	no	10.219	9.550	PhosphoSitePlus;EPSD	COSMIC	7.039	Down-regulation
TK_Abl_ABL1_Y	Q9UPY6	WASF3	P00519	ABL1	Y337	P343S	343	Missense	distal	6	no	10.219	10.247	PhosphoSitePlus;EPSD	COSMIC	7.039	Up-regulation
TK_Abl_ABL1_Y	Q9UPY6	WASF3	P00519	ABL1	Y337	P340T	340	Missense	distal	3	no	10.219	6.673	PhosphoSitePlus;EPSD	COSMIC;CCLE	7.039	Loss
TK_Abl_ABL1_Y	Q9UPY6	WASF3	P00519	ABL1	Y337	P340S	340	Missense	distal	3	no	10.219	7.084	PhosphoSitePlus;EPSD	COSMIC	7.039	Down-regulation
TK_Abl_ABL1_Y	Q9UPY6	WASF3	P00519	ABL1	Y337	I335S	335	Missense	proximal	-2	no	10.219	11.149	PhosphoSitePlus;EPSD	COSMIC	7.039	Up-regulation
TK_Abl_ABL1_Y	Q9UPY6	WASF3	P00519	ABL1	Y486	D488N	488	Missense	proximal	2	no	10.888	11.231	EPSD;PhosphoSitePlus	COSMIC	7.039	Up-regulation
TK_Abl_ABL1_Y	Q9UPY6	WASF3	P00519	ABL1	Y486	V484M	484	Missense	proximal	-2	no	10.888	10.161	EPSD;PhosphoSitePlus	COSMIC	7.039	Down-regulation
TK_Abl_ABL1_Y	P17844	DDX5	P00519	ABL1	Y59	K56N	56	Missense	distal	-3	no	7.456	7.798	EPSD	COSMIC	7.039	Up-regulation
TK_Abl_ABL1_Y	P17844	DDX5	P00519	ABL1	Y97	F101S	101	Missense	distal	4	no	10.141	10.442	EPSD	COSMIC;GDSC;CCLE	7.039	Up-regulation
TK_Abl_ABL1_Y	P17844	DDX5	P00519	ABL1	Y97	F96L	96	Missense	proximal	-1	no	10.141	10.928	EPSD	COSMIC	7.039	Up-regulation
TK_Abl_ABL1_Y	P17844	DDX5	P00519	ABL1	Y97	E98G	98	Missense	proximal	1	no	10.141	9.700	EPSD	COSMIC	7.039	Down-regulation
TK_Abl_ABL1_Y	P17844	DDX5	P00519	ABL1	Y97	L94M	94	Missense	distal	-3	no	10.141	10.395	EPSD	COSMIC	7.039	Up-regulation
TK_Abl_ABL1_Y	P17844	DDX5	P00519	ABL1	Y97	N95S	95	Missense	proximal	-2	no	10.141	10.255	EPSD	COSMIC	7.039	Up-regulation
TK_Abl_ABL1_Y	P17844	DDX5	P00519	ABL1	Y416	E423K	423	Missense	distal	7	no	9.066	9.098	EPSD	COSMIC	7.039	Up-regulation
TK_Abl_ABL1_Y	P17844	DDX5	P00519	ABL1	Y416	V410M	410	Missense	distal	-6	no	9.066	8.994	EPSD	COSMIC	7.039	Down-regulation
TK_Abl_ABL1_Y	P17844	DDX5	P00519	ABL1	Y416	N415S	415	Missense	proximal	-1	no	9.066	8.198	EPSD	COSMIC	7.039	Down-regulation
TK_Abl_ABL1_Y	P17844	DDX5	P00519	ABL1	Y416	Y418C	418	Missense	proximal	2	no	9.066	9.151	EPSD	COSMIC	7.039	Up-regulation
TK_Abl_ABL1_Y	P17844	DDX5	P00519	ABL1	Y535	G533S	533	Missense	proximal	-2	no	10.897	11.214	EPSD	COSMIC	7.039	Up-regulation
TK_Abl_ABL1_Y	P17844	DDX5	P00519	ABL1	Y535	T541I	541	Missense	distal	6	no	10.897	10.874	EPSD	COSMIC	7.039	Down-regulation
TK_Abl_ABL1_Y	P17844	DDX5	P00519	ABL1	Y535	Y535C	535	Missense	central	0	yes	10.897	0.000	EPSD	COSMIC;GDSC;CCLE	7.039	Loss
TK_Abl_ABL1_Y	P17844	DDX5	P00519	ABL1	Y535	Q531H	531	Missense	distal	-4	no	10.897	10.508	EPSD	COSMIC	7.039	Down-regulation
TK_Abl_ABL1_Y	P17844	DDX5	P00519	ABL1	Y593	A592T	592	Missense	proximal	-1	no	16.480	15.878	PhosphoSitePlus	COSMIC	7.039	Down-regulation
TK_Abl_ABL1_Y	P17844	DDX5	P00519	ABL1	Y595	A592T	592	Missense	distal	-3	no	8.959	8.296	EPSD	COSMIC	7.039	Down-regulation
TK_Abl_ABL1_Y	P17275	JUNB	P00519	ABL1	Y188	A193V	193	Missense	distal	5	no	7.733	7.662	PhosphoSitePlus;EPSD	COSMIC	7.039	Down-regulation
TK_Abl_ABL1_Y	O14818	PSMA7	P00519	ABL1	Y153	A158T	158	Missense	distal	5	no	11.538	11.147	PhosphoSitePlus;EPSD	COSMIC	7.039	Down-regulation
TK_Abl_ABL1_Y	O14818	PSMA7	P00519	ABL1	Y153	A155V	155	Missense	proximal	2	no	11.538	10.534	PhosphoSitePlus;EPSD	COSMIC	7.039	Down-regulation
TK_Abl_ABL1_Y	O14818	PSMA7	P00519	ABL1	Y153	T147S	147	Missense	distal	-6	no	11.538	11.658	PhosphoSitePlus;EPSD	COSMIC	7.039	Up-regulation
TK_Abl_ABL1_Y	O14818	PSMA7	P00519	ABL1	Y153	Q146H	146	Missense	distal	-7	no	11.538	10.994	PhosphoSitePlus;EPSD	COSMIC	7.039	Down-regulation
TK_Abl_ABL1_Y	O14818	PSMA7	P00519	ABL1	Y153	K157N	157	Missense	distal	4	no	11.538	11.827	PhosphoSitePlus;EPSD	COSMIC	7.039	Up-regulation
TK_Abl_ABL1_Y	Q9UPN9	TRIM33	P00519	ABL1	Y1018	Q1016L	1016	Missense	proximal	-2	no	11.528	10.228	EPSD	COSMIC	7.039	Down-regulation
TK_Abl_ABL1_Y	Q9UPN9	TRIM33	P00519	ABL1	Y1018	D1022N	1022	Missense	distal	4	no	11.528	11.569	EPSD	COSMIC;GDSC;CCLE	7.039	Up-regulation
TK_Abl_ABL1_Y	Q9UPN9	TRIM33	P00519	ABL1	Y1018	Q1011R	1011	Missense	distal	-7	no	11.528	11.183	EPSD	COSMIC	7.039	Down-regulation
TK_Abl_ABL1_Y	Q9UPN9	TRIM33	P00519	ABL1	Y1018	Q1016K	1016	Missense	proximal	-2	no	11.528	10.285	EPSD	COSMIC	7.039	Down-regulation
TK_Abl_ABL1_Y	P46527	CDKN1B	P00519	ABL1	Y88	P91S	91	Missense	distal	3	no	9.490	6.355	EPSD;PhosphoSitePlus	COSMIC	7.039	Loss
TK_Abl_ABL1_Y	P46527	CDKN1B	P00519	ABL1	Y88	R90K	90	Missense	proximal	2	no	9.490	9.439	EPSD;PhosphoSitePlus	COSMIC	7.039	Down-regulation
TK_Abl_ABL1_Y	P46527	CDKN1B	P00519	ABL1	Y88	R93W	93	Missense	distal	5	no	9.490	10.122	EPSD;PhosphoSitePlus	COSMIC	7.039	Up-regulation
TK_Abl_ABL1_Y	P46527	CDKN1B	P00519	ABL1	Y88	P94L	94	Missense	distal	6	no	9.490	8.821	EPSD;PhosphoSitePlus	COSMIC	7.039	Down-regulation
TK_Abl_ABL1_Y	P46527	CDKN1B	P00519	ABL1	Y88	Y88C	88	Missense	central	0	yes	9.490	0.000	EPSD;PhosphoSitePlus	COSMIC	7.039	Loss
TK_Abl_ABL1_Y	P46527	CDKN1B	P00519	ABL1	Y89	P91S	91	Missense	proximal	2	no	10.249	10.824	PhosphoSitePlus;EPSD	COSMIC	7.039	Up-regulation
TK_Abl_ABL1_Y	P46527	CDKN1B	P00519	ABL1	Y89	R90K	90	Missense	proximal	1	no	10.249	10.211	PhosphoSitePlus;EPSD	COSMIC	7.039	Down-regulation
TK_Abl_ABL1_Y	P46527	CDKN1B	P00519	ABL1	Y89	R93W	93	Missense	distal	4	no	10.249	9.599	PhosphoSitePlus;EPSD	COSMIC	7.039	Down-regulation
TK_Abl_ABL1_Y	P46527	CDKN1B	P00519	ABL1	Y89	P94L	94	Missense	distal	5	no	10.249	10.880	PhosphoSitePlus;EPSD	COSMIC	7.039	Up-regulation
TK_Abl_ABL1_Y	P46527	CDKN1B	P00519	ABL1	Y89	Y88C	88	Missense	proximal	-1	no	10.249	9.790	PhosphoSitePlus;EPSD	COSMIC	7.039	Down-regulation
TK_Abl_ABL1_Y	P06400	RB1	P00519	ABL1	Y606	R611S	611	Missense	distal	5	no	9.160	8.930	EPSD	COSMIC	7.039	Down-regulation
TK_Abl_ABL1_Y	P06400	RB1	P00519	ABL1	Y606	S612P	612	Missense	distal	6	no	9.160	9.132	EPSD	COSMIC	7.039	Down-regulation
TK_Abl_ABL1_Y	P06400	RB1	P00519	ABL1	Y606	Y606C	606	Missense	central	0	yes	9.160	0.000	EPSD	COSMIC	7.039	Loss
TK_Abl_ABL1_Y	P06400	RB1	P00519	ABL1	Y606	P609S	609	Missense	distal	3	no	9.160	6.025	EPSD	COSMIC	7.039	Loss
TK_Abl_ABL1_Y	P06400	RB1	P00519	ABL1	Y606	M605T	605	Missense	proximal	-1	no	9.160	9.919	EPSD	COSMIC	7.039	Up-regulation
TK_Abl_ABL1_Y	P06400	RB1	P00519	ABL1	Y606	N599D	599	Missense	distal	-7	no	9.160	8.607	EPSD	COSMIC	7.039	Down-regulation
TK_Abl_ABL1_Y	P06400	RB1	P00519	ABL1	Y606	L607V	607	Missense	proximal	1	no	9.160	10.970	EPSD	COSMIC	7.039	Up-regulation
TK_Abl_ABL1_Y	P06400	RB1	P00519	ABL1	Y606	L607I	607	Missense	proximal	1	no	9.160	10.184	EPSD	COSMIC	7.039	Up-regulation
TK_Abl_ABL1_Y	P06400	RB1	P00519	ABL1	Y805	G802R	802	Missense	distal	-3	no	10.355	10.531	PhosphoSitePlus	COSMIC	7.039	Up-regulation
TK_Abl_ABL1_Y	P06400	RB1	P00519	ABL1	Y805	R798Q	798	Missense	distal	-7	no	10.355	10.700	PhosphoSitePlus	COSMIC;GDSC;CCLE	7.039	Up-regulation
TK_Abl_ABL1_Y	P06400	RB1	P00519	ABL1	Y805	G801A	801	Missense	distal	-4	no	10.355	9.829	PhosphoSitePlus	COSMIC	7.039	Down-regulation
TK_Abl_ABL1_Y	O00429	DNM1L	P00519	ABL1	Y266	R263C	263	Missense	distal	-3	no	7.695	7.679	EPSD;PhosphoSitePlus	COSMIC	7.039	Down-regulation
TK_Abl_ABL1_Y	O00429	DNM1L	P00519	ABL1	Y266	D260N	260	Missense	distal	-6	no	7.695	7.688	EPSD;PhosphoSitePlus	COSMIC	7.039	Down-regulation
TK_Abl_ABL1_Y	O00429	DNM1L	P00519	ABL1	Y266	L269F	269	Missense	distal	3	no	7.695	8.363	EPSD;PhosphoSitePlus	COSMIC	7.039	Up-regulation
TK_Abl_ABL1_Y	O00429	DNM1L	P00519	ABL1	Y449	I442T	442	Missense	distal	-7	no	7.069	7.687	EPSD;PhosphoSitePlus	COSMIC	7.039	Up-regulation
TK_Abl_ABL1_Y	O00429	DNM1L	P00519	ABL1	Y449	R456Q	456	Missense	distal	7	no	7.069	7.097	EPSD;PhosphoSitePlus	COSMIC	7.039	Up-regulation
TK_Abl_ABL1_Y	O00429	DNM1L	P00519	ABL1	Y449	I443V	443	Missense	distal	-6	no	7.069	7.049	EPSD;PhosphoSitePlus	COSMIC;GDSC;CCLE	7.039	Down-regulation
TK_Abl_ABL1_Y	O00429	DNM1L	P00519	ABL1	Y449	R456S	456	Missense	distal	7	no	7.069	7.055	EPSD;PhosphoSitePlus	COSMIC	7.039	Down-regulation
TK_Abl_ABL1_Y	Q00987	MDM2	P00519	ABL1	Y276	D272N	272	Missense	distal	-4	no	7.453	7.830	EPSD;PhosphoSitePlus	COSMIC	7.039	Up-regulation
TK_Abl_ABL1_Y	Q00987	MDM2	P00519	ABL1	Y276	Y276C	276	Missense	central	0	yes	7.453	0.000	EPSD;PhosphoSitePlus	COSMIC	7.039	Loss
TK_Abl_ABL1_Y	Q00987	MDM2	P00519	ABL1	Y276	Y276H	276	Missense	central	0	yes	7.453	0.000	EPSD;PhosphoSitePlus	COSMIC	7.039	Loss
TK_Abl_ABL1_Y	Q00987	MDM2	P00519	ABL1	Y276	A283T	283	Missense	distal	7	no	7.453	7.505	EPSD;PhosphoSitePlus	COSMIC	7.039	Up-regulation
TK_Abl_ABL1_Y	Q00987	MDM2	P00519	ABL1	Y276	Y281H	281	Missense	distal	5	no	7.453	7.305	EPSD;PhosphoSitePlus	COSMIC	7.039	Down-regulation
TK_Abl_ABL1_Y	Q00987	MDM2	P00519	ABL1	Y276	T279P	279	Missense	distal	3	no	7.453	10.998	EPSD;PhosphoSitePlus	COSMIC	7.039	Up-regulation
TK_Abl_ABL1_Y	Q00987	MDM2	P00519	ABL1	Y276	V278D	278	Missense	proximal	2	no	7.453	7.929	EPSD;PhosphoSitePlus	COSMIC	7.039	Up-regulation
TK_Abl_ABL1_Y	Q00987	MDM2	P00519	ABL1	Y276	V278A	278	Missense	proximal	2	no	7.453	8.456	EPSD;PhosphoSitePlus	COSMIC	7.039	Up-regulation
TK_Abl_ABL1_Y	Q00987	MDM2	P00519	ABL1	Y276	E271D	271	Missense	distal	-5	no	7.453	7.393	EPSD;PhosphoSitePlus	COSMIC	7.039	Down-regulation
TK_Abl_ABL1_Y	Q00987	MDM2	P00519	ABL1	Y394	D393E	393	Missense	proximal	-1	no	10.889	11.570	PhosphoSitePlus;EPSD	COSMIC	7.039	Up-regulation
TK_Abl_ABL1_Y	Q00987	MDM2	P00519	ABL1	Y394	D393H	393	Missense	proximal	-1	no	10.889	11.238	PhosphoSitePlus;EPSD	COSMIC	7.039	Up-regulation
TK_Abl_ABL1_Y	Q00987	MDM2	P00519	ABL1	Y405	S407R	407	Missense	proximal	2	no	8.088	7.239	EPSD;PhosphoSitePlus	COSMIC	7.039	Down-regulation
TK_Abl_ABL1_Y	Q00987	MDM2	P00519	ABL1	Y405	S407G	407	Missense	proximal	2	no	8.088	7.298	EPSD;PhosphoSitePlus	COSMIC	7.039	Down-regulation
TK_Abl_ABL1_Y	Q00987	MDM2	P00519	ABL1	Y405	I403V	403	Missense	proximal	-2	no	8.088	8.826	EPSD;PhosphoSitePlus	COSMIC	7.039	Up-regulation
TK_Abl_ABL1_Y	Q00987	MDM2	P00519	ABL1	Y405	Y405C	405	Missense	central	0	yes	8.088	0.000	EPSD;PhosphoSitePlus	COSMIC	7.039	Loss
TK_Abl_ABL1_Y	Q00987	MDM2	P00519	ABL1	Y405	S407N	407	Missense	proximal	2	no	8.088	7.706	EPSD;PhosphoSitePlus	COSMIC	7.039	Down-regulation
TK_Abl_ABL1_Y	Q9H7P9	PLEKHG2	P00519	ABL1	Y489	P484L	484	Missense	distal	-5	no	9.024	7.625	PhosphoSitePlus	COSMIC;GDSC;CCLE	7.039	Down-regulation
TK_Abl_ABL1_Y	Q9H7P9	PLEKHG2	P00519	ABL1	Y489	A496T	496	Missense	distal	7	no	9.024	9.076	PhosphoSitePlus	COSMIC;GDSC	7.039	Up-regulation
TK_Abl_ABL1_Y	Q9H7P9	PLEKHG2	P00519	ABL1	Y489	P493S	493	Missense	distal	4	no	9.024	8.744	PhosphoSitePlus	COSMIC	7.039	Down-regulation
TK_Abl_ABL1_Y	Q9H7P9	PLEKHG2	P00519	ABL1	Y489	V485M	485	Missense	distal	-4	no	9.024	8.274	PhosphoSitePlus	COSMIC	7.039	Down-regulation
TK_Abl_ABL1_Y	Q16531	DDB1	P00519	ABL1	Y182	V181A	181	Missense	proximal	-1	no	10.384	10.836	PhosphoSitePlus;EPSD	COSMIC	7.039	Up-regulation
TK_Abl_ABL1_Y	Q16531	DDB1	P00519	ABL1	Y182	P176S	176	Missense	distal	-6	no	10.384	10.403	PhosphoSitePlus;EPSD	COSMIC;GDSC;CCLE	7.039	Up-regulation
TK_Abl_ABL1_Y	Q16531	DDB1	P00519	ABL1	Y517	Q524R	524	Missense	distal	7	no	7.406	7.377	EPSD	COSMIC	7.039	Down-regulation
TK_Abl_ABL1_Y	Q16531	DDB1	P00519	ABL1	Y660	I659M	659	Missense	proximal	-1	no	7.460	4.784	EPSD	COSMIC	7.039	Loss
TK_Abl_ABL1_Y	Q16531	DDB1	P00519	ABL1	Y718	P721L	721	Missense	distal	3	no	7.222	4.645	EPSD;PhosphoSitePlus	COSMIC	7.039	Loss
TK_Abl_ABL1_Y	Q16531	DDB1	P00519	ABL1	Y718	P716L	716	Missense	proximal	-2	no	7.222	6.637	EPSD;PhosphoSitePlus	COSMIC	7.039	Loss
TK_Abl_ABL1_Y	Q13905	RAPGEF1	P00519	ABL1	Y155	S148N	148	Missense	distal	-7	no	8.080	8.748	EPSD	COSMIC	7.039	Up-regulation
TK_Abl_ABL1_Y	Q13905	RAPGEF1	P00519	ABL1	Y504	A505G	505	Missense	proximal	1	no	8.111	6.564	PhosphoSitePlus	COSMIC	7.039	Loss
TK_Abl_ABL1_Y	Q13905	RAPGEF1	P00519	ABL1	Y504	A509V	509	Missense	distal	5	no	8.111	8.040	PhosphoSitePlus	COSMIC	7.039	Down-regulation
TK_Abl_ABL1_Y	Q13905	RAPGEF1	P00519	ABL1	Y504	P498T	498	Missense	distal	-6	no	8.111	8.009	PhosphoSitePlus	COSMIC	7.039	Down-regulation
TK_Abl_ABL1_Y	Q13905	RAPGEF1	P00519	ABL1	Y504	A505T	505	Missense	proximal	1	no	8.111	6.844	PhosphoSitePlus	COSMIC	7.039	Loss
TK_Abl_ABL1_Y	Q13905	RAPGEF1	P00519	ABL1	Y504	V502I	502	Missense	proximal	-2	no	8.111	7.373	PhosphoSitePlus	COSMIC	7.039	Down-regulation
TK_Abl_ABL1_Y	Q13905	RAPGEF1	P00519	ABL1	Y504	A505V	505	Missense	proximal	1	no	8.111	7.093	PhosphoSitePlus	COSMIC	7.039	Down-regulation
TK_Abl_ABL1_Y	Q13905	RAPGEF1	P00519	ABL1	Y504	L511P	511	Missense	distal	7	no	8.111	8.121	PhosphoSitePlus	COSMIC	7.039	Up-regulation
TK_Abl_ABL1_Y	Q13905	RAPGEF1	P00519	ABL1	Y579	L585R	585	Missense	distal	6	no	7.018	7.579	EPSD	COSMIC	7.039	Gain
TK_Abl_ABL1_Y	P35222	CTNNB1	P00519	ABL1	Y86	Y86H	86	Missense	central	0	yes	8.309	0.000	EPSD;PhosphoSitePlus	COSMIC	7.039	Loss
TK_Abl_ABL1_Y	P35222	CTNNB1	P00519	ABL1	Y86	V79I	79	Missense	distal	-7	no	8.309	7.770	EPSD;PhosphoSitePlus	COSMIC	7.039	Down-regulation
TK_Abl_ABL1_Y	P35222	CTNNB1	P00519	ABL1	Y86	R93S	93	Missense	distal	7	no	8.309	8.295	EPSD;PhosphoSitePlus	COSMIC	7.039	Down-regulation
TK_Abl_ABL1_Y	P35222	CTNNB1	P00519	ABL1	Y86	D83N	83	Missense	distal	-3	no	8.309	8.273	EPSD;PhosphoSitePlus	COSMIC	7.039	Down-regulation
TK_Abl_ABL1_Y	P35222	CTNNB1	P00519	ABL1	Y86	I82F	82	Missense	distal	-4	no	8.309	6.636	EPSD;PhosphoSitePlus	COSMIC	7.039	Loss
TK_Abl_ABL1_Y	P35222	CTNNB1	P00519	ABL1	Y86	M88V	88	Missense	proximal	2	no	8.309	7.767	EPSD;PhosphoSitePlus	COSMIC	7.039	Down-regulation
TK_Abl_ABL1_Y	P35222	CTNNB1	P00519	ABL1	Y86	I82V	82	Missense	distal	-4	no	8.309	8.214	EPSD;PhosphoSitePlus	COSMIC	7.039	Down-regulation
TK_Abl_ABL1_Y	P35222	CTNNB1	P00519	ABL1	Y333	L336V	336	Missense	distal	3	no	6.591	7.248	EPSD	COSMIC	7.039	Gain
TK_Abl_ABL1_Y	P35222	CTNNB1	P00519	ABL1	Y333	K335Q	335	Missense	proximal	2	no	6.591	7.091	EPSD	COSMIC	7.039	Gain
TK_Abl_ABL1_Y	P35222	CTNNB1	P00519	ABL1	Y489	K496T	496	Missense	distal	7	no	10.410	10.434	PhosphoSitePlus;EPSD	COSMIC	7.039	Up-regulation
TK_Abl_ABL1_Y	P35222	CTNNB1	P00519	ABL1	Y489	R486C	486	Missense	distal	-3	no	10.410	10.394	PhosphoSitePlus;EPSD	COSMIC	7.039	Down-regulation
TK_Abl_ABL1_Y	P35222	CTNNB1	P00519	ABL1	Y489	V495G	495	Missense	distal	6	no	10.410	10.024	PhosphoSitePlus;EPSD	COSMIC	7.039	Down-regulation
TK_Abl_ABL1_Y	P35222	CTNNB1	P00519	ABL1	Y489	R486H	486	Missense	distal	-3	no	10.410	9.616	PhosphoSitePlus;EPSD	COSMIC;CCLE	7.039	Down-regulation
TK_Abl_ABL1_Y	P35222	CTNNB1	P00519	ABL1	Y654	A657T	657	Missense	distal	3	no	6.683	7.240	EPSD;PhosphoSitePlus	COSMIC	7.039	Gain
TK_Abl_ABL1_Y	P35222	CTNNB1	P00519	ABL1	Y654	A652V	652	Missense	proximal	-2	no	6.683	7.143	EPSD;PhosphoSitePlus	COSMIC	7.039	Gain
TK_Abl_ABL1_Y	P35222	CTNNB1	P00519	ABL1	Y716	Y716C	716	Missense	central	0	yes	7.966	0.000	EPSD	COSMIC	7.039	Loss
TK_Abl_ABL1_Y	P35222	CTNNB1	P00519	ABL1	Y716	H720P	720	Missense	distal	4	no	7.966	8.762	EPSD	COSMIC	7.039	Up-regulation
TK_Abl_ABL1_Y	P35222	CTNNB1	P00519	ABL1	Y716	R717C	717	Missense	proximal	1	no	7.966	7.194	EPSD	COSMIC	7.039	Down-regulation
TK_Abl_ABL1_Y	P35222	CTNNB1	P00519	ABL1	Y716	S715R	715	Missense	proximal	-1	no	7.966	7.744	EPSD	COSMIC	7.039	Down-regulation
TK_Abl_ABL1_Y	P35222	CTNNB1	P00519	ABL1	Y716	D712N	712	Missense	distal	-4	no	7.966	8.344	EPSD	COSMIC	7.039	Up-regulation
TK_Abl_ABL1_Y	P35222	CTNNB1	P00519	ABL1	Y716	P714S	714	Missense	proximal	-2	no	7.966	8.358	EPSD	COSMIC	7.039	Up-regulation
TK_Abl_ABL1_Y	P35222	CTNNB1	P00519	ABL1	Y716	Y709C	709	Missense	distal	-7	no	7.966	7.904	EPSD	COSMIC	7.039	Down-regulation
TK_Abl_ABL1_Y	P35222	CTNNB1	P00519	ABL1	Y716	R710C	710	Missense	distal	-6	no	7.966	7.756	EPSD	COSMIC	7.039	Down-regulation
TK_Abl_ABL1_Y	P35222	CTNNB1	P00519	ABL1	Y716	G723S	723	Missense	distal	7	no	7.966	7.980	EPSD	COSMIC	7.039	Up-regulation
TK_Abl_ABL1_Y	P43403	ZAP70	P00519	ABL1	Y69	L65V	65	Missense	distal	-4	no	6.877	8.002	EPSD	COSMIC	7.039	Gain
TK_Abl_ABL1_Y	P43403	ZAP70	P00519	ABL1	Y69	E62K	62	Missense	distal	-7	no	6.877	7.118	EPSD	COSMIC;CCLE	7.039	Gain
TK_Abl_ABL1_Y	P43403	ZAP70	P00519	ABL1	Y221	G219E	219	Missense	proximal	-2	no	10.683	10.752	EPSD	COSMIC	7.039	Up-regulation
TK_Abl_ABL1_Y	P43403	ZAP70	P00519	ABL1	Y221	E225K	225	Missense	distal	4	no	10.683	10.309	EPSD	COSMIC	7.039	Down-regulation
TK_Abl_ABL1_Y	P43403	ZAP70	P00519	ABL1	Y319	T312M	312	Missense	distal	-7	no	13.297	13.150	PhosphoSitePlus	COSMIC	7.039	Down-regulation
TK_Abl_ABL1_Y	P43403	ZAP70	P00519	ABL1	Y597	R592H	592	Missense	distal	-5	no	9.155	7.387	EPSD	COSMIC	7.039	Down-regulation
TK_Abl_ABL1_Y	P43403	ZAP70	P00519	ABL1	Y597	S602R	602	Missense	distal	5	no	9.155	9.385	EPSD	COSMIC;CCLE	7.039	Up-regulation
TK_Abl_ABL1_Y	P43403	ZAP70	P00519	ABL1	Y597	E590K	590	Missense	distal	-7	no	9.155	9.396	EPSD	COSMIC	7.039	Up-regulation
TK_Abl_ABL1_Y	P43403	ZAP70	P00519	ABL1	Y598	R592H	592	Missense	distal	-6	no	7.684	7.512	EPSD	COSMIC	7.039	Down-regulation
TK_Abl_ABL1_Y	P43403	ZAP70	P00519	ABL1	Y598	S602R	602	Missense	distal	4	no	7.684	7.966	EPSD	COSMIC;CCLE	7.039	Up-regulation
TK_Abl_ABL1_Y	Q8IZP0	ABI1	P00519	ABL1	Y213	T215N	215	Missense	proximal	2	no	9.483	9.492	PhosphoSitePlus	COSMIC	7.039	Up-regulation
TK_Abl_ABL1_Y	Q8IZP0	ABI1	P00519	ABL1	Y213	P207S	207	Missense	distal	-6	no	9.483	9.501	PhosphoSitePlus	COSMIC	7.039	Up-regulation
TK_Abl_ABL1_Y	Q8IZP0	ABI1	P00519	ABL1	Y213	P217L	217	Missense	distal	4	no	9.483	9.085	PhosphoSitePlus	COSMIC	7.039	Down-regulation
TK_Abl_ABL1_Y	Q8IZP0	ABI1	P00519	ABL1	Y431	G438W	438	Missense	distal	7	no	7.974	7.973	EPSD	COSMIC	7.039	Down-regulation
TK_Abl_ABL1_Y	Q8IZP0	ABI1	P00519	ABL1	Y431	G438V	438	Missense	distal	7	no	7.974	8.002	EPSD	COSMIC	7.039	Up-regulation
TK_Abl_ABL1_Y	Q8IZP0	ABI1	P00519	ABL1	Y431	Y435C	435	Missense	distal	4	no	7.974	8.083	EPSD	COSMIC	7.039	Up-regulation
TK_Abl_ABL1_Y	Q8IZP0	ABI1	P00519	ABL1	Y431	D433N	433	Missense	proximal	2	no	7.974	8.317	EPSD	COSMIC	7.039	Up-regulation
TK_Abl_ABL1_Y	Q8IZP0	ABI1	P00519	ABL1	Y431	A426T	426	Missense	distal	-5	no	7.974	8.365	EPSD	COSMIC	7.039	Up-regulation
TK_Abl_ABL1_Y	Q8IZP0	ABI1	P00519	ABL1	Y431	A426P	426	Missense	distal	-5	no	7.974	7.823	EPSD	COSMIC	7.039	Down-regulation
TK_Abl_ABL1_Y	Q8IZP0	ABI1	P00519	ABL1	Y455	A453P	453	Missense	proximal	-2	no	8.579	8.838	EPSD	COSMIC	7.039	Up-regulation
TK_Abl_ABL1_Y	Q8IZP0	ABI1	P00519	ABL1	Y455	D460N	460	Missense	distal	5	no	8.579	7.921	EPSD	COSMIC	7.039	Down-regulation
TK_Abl_ABL1_Y	Q8IZP0	ABI1	P00519	ABL1	Y474	A471T	471	Missense	distal	-3	no	7.780	7.117	EPSD	COSMIC	7.039	Down-regulation
TK_Abl_ABL1_Y	Q8IZP0	ABI1	P00519	ABL1	Y474	G470V	470	Missense	distal	-4	no	7.780	7.476	EPSD	COSMIC	7.039	Down-regulation
TK_Abl_ABL1_Y	O60260	PRKN	P00519	ABL1	Y143	S141L	141	Missense	proximal	-2	no	10.769	9.791	PhosphoSitePlus	COSMIC	7.039	Down-regulation
TK_Abl_ABL1_Y	O60260	PRKN	P00519	ABL1	Y143	S145N	145	Missense	proximal	2	no	10.769	10.387	PhosphoSitePlus	COSMIC	7.039	Down-regulation
TK_Abl_ABL1_Y	O60260	PRKN	P00519	ABL1	Y143	Y149C	149	Missense	distal	6	no	10.769	10.221	PhosphoSitePlus	COSMIC	7.039	Down-regulation
TK_Abl_ABL1_Y	O60260	PRKN	P00519	ABL1	Y143	C150F	150	Missense	distal	7	no	10.769	10.768	PhosphoSitePlus	COSMIC	7.039	Down-regulation
TK_Abl_ABL1_Y	O60260	PRKN	P00519	ABL1	Y143	V148L	148	Missense	distal	5	no	10.769	11.312	PhosphoSitePlus	COSMIC	7.039	Up-regulation
TK_Abl_ABL1_Y	O60260	PRKN	P00519	ABL1	Y143	A138P	138	Missense	distal	-5	no	10.769	10.618	PhosphoSitePlus	COSMIC	7.039	Down-regulation
TK_Abl_ABL1_Y	O60260	PRKN	P00519	ABL1	Y143	A138E	138	Missense	distal	-5	no	10.769	10.578	PhosphoSitePlus	COSMIC	7.039	Down-regulation
TK_Abl_ABL1_Y	O60260	PRKN	P00519	ABL1	Y143	S145I	145	Missense	proximal	2	no	10.769	10.543	PhosphoSitePlus	COSMIC	7.039	Down-regulation
TK_Abl_ABL1_Y	P15391	CD19	P00519	ABL1	Y378	G373S	373	Missense	distal	-5	no	7.896	8.245	EPSD	COSMIC	7.039	Up-regulation
TK_Abl_ABL1_Y	P15391	CD19	P00519	ABL1	Y378	S377P	377	Missense	proximal	-1	no	7.896	9.485	EPSD	COSMIC	7.039	Up-regulation
TK_Abl_ABL1_Y	P15391	CD19	P00519	ABL1	Y500	M503I	503	Missense	distal	3	no	7.261	6.752	EPSD	COSMIC	7.039	Loss
TK_Abl_ABL1_Y	P15391	CD19	P00519	ABL1	Y500	E501K	501	Missense	proximal	1	no	7.261	6.721	EPSD	COSMIC	7.039	Loss
TK_Abl_ABL1_Y	P15391	CD19	P00519	ABL1	Y500	Y500C	500	Missense	central	0	yes	7.261	0.000	EPSD	COSMIC	7.039	Loss
TK_Abl_ABL1_Y	P15391	CD19	P00519	ABL1	Y500	S497F	497	Missense	distal	-3	no	7.261	5.837	EPSD	COSMIC	7.039	Loss
TK_Abl_ABL1_Y	P15391	CD19	P00519	ABL1	Y500	D502N	502	Missense	proximal	2	no	7.261	7.604	EPSD	COSMIC	7.039	Up-regulation
TK_Abl_ABL1_Y	P15391	CD19	P00519	ABL1	Y500	G496E	496	Missense	distal	-4	no	7.261	8.308	EPSD	COSMIC	7.039	Up-regulation
TK_Abl_ABL1_Y	P15391	CD19	P00519	ABL1	Y508	M503I	503	Missense	distal	-5	no	9.625	8.957	PhosphoSitePlus	COSMIC	7.039	Down-regulation
TK_Abl_ABL1_Y	P15391	CD19	P00519	ABL1	Y508	E501K	501	Missense	distal	-7	no	9.625	9.866	PhosphoSitePlus	COSMIC	7.039	Up-regulation
TK_Abl_ABL1_Y	P15391	CD19	P00519	ABL1	Y508	D502N	502	Missense	distal	-6	no	9.625	9.618	PhosphoSitePlus	COSMIC	7.039	Down-regulation
TK_Abl_ABL1_Y	P15391	CD19	P00519	ABL1	Y531	P537T	537	Missense	distal	6	no	7.945	7.876	EPSD	COSMIC;CCLE	7.039	Down-regulation
TK_Abl_ABL1_Y	P15391	CD19	P00519	ABL1	Y531	D529A	529	Missense	proximal	-2	no	7.945	8.003	EPSD	COSMIC	7.039	Up-regulation
TK_Abl_ABL1_Y	P15391	CD19	P00519	ABL1	Y531	N533S	533	Missense	proximal	2	no	7.945	8.327	EPSD	COSMIC	7.039	Up-regulation
TK_Abl_ABL1_Y	P15391	CD19	P00519	ABL1	Y531	M534I	534	Missense	distal	3	no	7.945	7.435	EPSD	COSMIC	7.039	Down-regulation
TK_Abl_ABL1_Y	P15391	CD19	P00519	ABL1	Y531	E532K	532	Missense	proximal	1	no	7.945	7.405	EPSD	COSMIC	7.039	Down-regulation
TK_Abl_ABL1_Y	P15391	CD19	P00519	ABL1	Y531	D529N	529	Missense	proximal	-2	no	7.945	8.541	EPSD	COSMIC	7.039	Up-regulation
TK_Abl_ABL1_Y	O15269	SPTLC1	P00519	ABL1	Y18	E19G	19	Missense	proximal	1	no	7.111	6.670	EPSD	COSMIC	7.039	Loss
TK_Abl_ABL1_Y	O15269	SPTLC1	P00519	ABL1	Y18	M13I	13	Missense	distal	-5	no	7.111	6.442	EPSD	COSMIC	7.039	Loss
TK_Abl_ABL1_Y	Q9Y6H1	CHCHD2	P00519	ABL1	Y99	P92F	92	Missense	distal	-7	no	11.718	11.317	PhosphoSitePlus	COSMIC	7.039	Down-regulation
TK_Abl_ABL1_Y	O94916	NFAT5	P00519	ABL1	Y28	K33N	33	Missense	distal	5	no	8.256	7.261	EPSD	COSMIC	7.039	Down-regulation
TK_Abl_ABL1_Y	O94916	NFAT5	P00519	ABL1	Y143	P146L	146	Missense	distal	3	no	7.417	4.839	PhosphoSitePlus	COSMIC	7.039	Loss
TK_Abl_ABL1_Y	Q92769	HDAC2	P00519	ABL1	Y55	R56M	56	Missense	proximal	1	no	7.185	7.683	EPSD	COSMIC	7.039	Up-regulation
TK_Abl_ABL1_Y	Q92769	HDAC2	P00519	ABL1	Y68	E72D	72	Missense	distal	4	no	7.646	7.518	EPSD	COSMIC	7.039	Down-regulation
TK_Abl_ABL1_Y	Q92769	HDAC2	P00519	ABL1	Y68	H69N	69	Missense	proximal	1	no	7.646	9.400	EPSD	COSMIC	7.039	Up-regulation
TK_Abl_ABL1_Y	Q92769	HDAC2	P00519	ABL1	Y68	M65V	65	Missense	distal	-3	no	7.646	7.959	EPSD	COSMIC	7.039	Up-regulation
TK_Abl_ABL1_Y	Q92769	HDAC2	P00519	ABL1	Y88	K90N	90	Missense	proximal	2	no	7.312	7.831	EPSD	COSMIC	7.039	Up-regulation
TK_Abl_ABL1_Y	Q92769	HDAC2	P00519	ABL1	Y222	P228Q	228	Missense	distal	6	no	6.757	7.501	PhosphoSitePlus	COSMIC	7.039	Gain
TK_Abl_ABL1_Y	Q92769	HDAC2	P00519	ABL1	Y222	I215S	215	Missense	distal	-7	no	6.757	7.078	PhosphoSitePlus	COSMIC	7.039	Gain
TK_Abl_ABL1_Y	Q92769	HDAC2	P00519	ABL1	Y359	Q354L	354	Missense	distal	-5	no	9.001	7.333	EPSD	COSMIC	7.039	Down-regulation
TK_Abl_ABL1_Y	Q92769	HDAC2	P00519	ABL1	Y359	I363M	363	Missense	distal	4	no	9.001	8.618	EPSD	COSMIC	7.039	Down-regulation
TK_Abl_ABL1_Y	Q92769	HDAC2	P00519	ABL1	Y359	R366H	366	Missense	distal	7	no	9.001	8.973	EPSD	COSMIC	7.039	Down-regulation
TK_Abl_ABL1_Y	Q9H2X6	HIPK2	P00519	ABL1	Y367	P370Q	370	Missense	distal	3	no	8.524	5.509	PhosphoSitePlus	COSMIC	7.039	Loss
TK_Abl_ABL1_Y	Q9H2X6	HIPK2	P00519	ABL1	Y443	R447K	447	Missense	distal	4	no	9.217	8.940	EPSD	COSMIC	7.039	Down-regulation
TK_Abl_ABL1_Y	Q9H2X6	HIPK2	P00519	ABL1	Y443	P444A	444	Missense	proximal	1	no	9.217	11.301	EPSD	COSMIC	7.039	Up-regulation
TK_Abl_ABL1_Y	Q9H2X6	HIPK2	P00519	ABL1	Y1197	Y1195C	1195	Missense	proximal	-2	no	8.206	7.910	EPSD	COSMIC	7.039	Down-regulation
TK_Abl_ABL1_Y	Q9H2X6	HIPK2	P00519	ABL1	Y1197	P1196S	1196	Missense	proximal	-1	no	8.206	6.616	EPSD	COSMIC	7.039	Loss
TK_Abl_ABL1_Y	Q9H2X6	HIPK2	P00519	ABL1	Y1197	Y1197S	1197	Missense	central	0	yes	8.206	0.000	EPSD	COSMIC	7.039	Loss
TK_Abl_ABL1_Y	Q14847	LASP1	P00519	ABL1	Y152	E157D	157	Missense	distal	5	no	8.228	8.585	EPSD	COSMIC	7.039	Up-regulation
TK_Abl_ABL1_Y	Q14847	LASP1	P00519	ABL1	Y152	R153W	153	Missense	proximal	1	no	8.228	5.452	EPSD	COSMIC;GDSC	7.039	Loss
TK_Abl_ABL1_Y	Q14847	LASP1	P00519	ABL1	Y152	E157K	157	Missense	distal	5	no	8.228	8.922	EPSD	COSMIC	7.039	Up-regulation
TK_Abl_ABL1_Y	Q14847	LASP1	P00519	ABL1	Y152	G149D	149	Missense	distal	-3	no	8.228	8.462	EPSD	COSMIC	7.039	Up-regulation
TK_Abl_ABL1_Y	Q14847	LASP1	P00519	ABL1	Y171	P174T	174	Missense	distal	3	no	10.568	7.023	PhosphoSitePlus	COSMIC	7.039	Loss
TK_Abl_ABL1_Y	Q14847	LASP1	P00519	ABL1	Y171	P165L	165	Missense	distal	-6	no	10.568	10.416	PhosphoSitePlus	COSMIC	7.039	Down-regulation
TK_Abl_ABL1_Y	Q15139	PRKD1	P00519	ABL1	Y463	G459E	459	Missense	distal	-4	no	11.364	12.412	PhosphoSitePlus	COSMIC	7.039	Up-regulation
TK_Abl_ABL1_Y	Q15139	PRKD1	P00519	ABL1	Y463	P467S	467	Missense	distal	4	no	11.364	11.084	PhosphoSitePlus	COSMIC	7.039	Down-regulation
TK_Abl_ABL1_Y	Q15139	PRKD1	P00519	ABL1	Y463	K464N	464	Missense	proximal	1	no	11.364	12.036	PhosphoSitePlus	COSMIC	7.039	Up-regulation
TK_Abl_ABL1_Y	O95433	AHSA1	P00519	ABL1	Y223	E220K	220	Missense	distal	-3	no	9.095	8.068	PhosphoSitePlus	COSMIC;GDSC;CCLE	7.039	Down-regulation
TK_Abl_ABL1_Y	P25490	YY1	P00519	ABL1	Y8	D5N	5	Missense	distal	-3	no	7.082	7.046	EPSD	COSMIC	7.039	Down-regulation
TK_Abl_ABL1_Y	P25490	YY1	P00519	ABL1	Y383	R381M	381	Missense	proximal	-2	no	8.028	7.877	EPSD	COSMIC;CCLE	7.039	Down-regulation
TK_Abl_ABL1_Y	P25490	YY1	P00519	ABL1	Y383	C385F	385	Missense	proximal	2	no	8.028	7.971	EPSD	COSMIC	7.039	Down-regulation
TK_Abl_ABL1_Y	P42768	WAS	P00519	ABL1	Y102	T109P	109	Missense	distal	7	no	7.430	7.406	EPSD	COSMIC	7.039	Down-regulation
TK_Abl_ABL1_Y	P42768	WAS	P00519	ABL1	Y102	E100K	100	Missense	proximal	-2	no	7.430	6.757	EPSD	COSMIC	7.039	Loss
TK_Abl_ABL1_Y	P42768	WAS	P00519	ABL1	Y102	W97C	97	Missense	distal	-5	no	7.430	7.907	EPSD	COSMIC	7.039	Up-regulation
TK_Abl_ABL1_Y	P11387	TOP1	P00519	ABL1	Y125	F126S	126	Missense	proximal	1	no	8.928	11.227	EPSD	COSMIC	7.039	Up-regulation
TK_Abl_ABL1_Y	P11387	TOP1	P00519	ABL1	Y231	E236K	236	Missense	distal	5	no	7.441	8.135	EPSD	COSMIC	7.039	Up-regulation
TK_Abl_ABL1_Y	P11387	TOP1	P00519	ABL1	Y231	P235T	235	Missense	distal	4	no	7.441	7.362	EPSD	COSMIC;GDSC;CCLE	7.039	Down-regulation
TK_Abl_ABL1_Y	P11387	TOP1	P00519	ABL1	Y231	P229L	229	Missense	proximal	-2	no	7.441	6.855	EPSD	COSMIC	7.039	Loss
TK_Abl_ABL1_Y	P11387	TOP1	P00519	ABL1	Y231	V238A	238	Missense	distal	7	no	7.441	7.408	EPSD	COSMIC	7.039	Down-regulation
TK_Abl_ABL1_Y	P11387	TOP1	P00519	ABL1	Y268	D265N	265	Missense	distal	-3	no	10.618	10.582	PhosphoSitePlus	COSMIC	7.039	Down-regulation
TK_Abl_ABL1_Y	P11387	TOP1	P00519	ABL1	Y268	D265Y	265	Missense	distal	-3	no	10.618	10.644	PhosphoSitePlus	COSMIC	7.039	Up-regulation
TK_Abl_ABL1_Y	P11387	TOP1	P00519	ABL1	Y537	Y537H	537	Missense	central	0	yes	7.140	0.000	EPSD	COSMIC	7.039	Loss
TK_Abl_ABL1_Y	P11387	TOP1	P00519	ABL1	Y537	R536G	536	Missense	proximal	-1	no	7.140	6.509	EPSD	COSMIC	7.039	Loss
TK_Abl_ABL1_Y	P11387	TOP1	P00519	ABL1	Y537	V541I	541	Missense	distal	4	no	7.140	7.347	EPSD	COSMIC	7.039	Up-regulation
TK_Abl_ABL1_Y	P11387	TOP1	P00519	ABL1	Y537	I535M	535	Missense	proximal	-2	no	7.140	7.151	EPSD	COSMIC	7.039	Up-regulation
TK_Abl_ABL1_Y	P11387	TOP1	P00519	ABL1	Y537	G531R	531	Missense	distal	-6	no	7.140	7.358	EPSD	COSMIC	7.039	Up-regulation
TK_Abl_ABL1_Y	P11387	TOP1	P00519	ABL1	Y538	R536G	536	Missense	proximal	-2	no	6.782	7.233	EPSD	COSMIC	7.039	Gain
Other_CDC7_CDC7_ST	P19338	NCL	O00311	CDC7	S41	D36N	36	Missense	distal	-5	no	72.467	73.929	EPSD	COSMIC	65.097	Up-regulation
Other_CDC7_CDC7_ST	P19338	NCL	O00311	CDC7	T92	V98I	98	Missense	distal	6	no	65.862	66.189	EPSD	COSMIC	65.097	Up-regulation
Other_CDC7_CDC7_ST	P19338	NCL	O00311	CDC7	T92	P93H	93	Missense	proximal	1	no	65.862	37.110	EPSD	COSMIC	65.097	Loss
Other_CDC7_CDC7_ST	P19338	NCL	O00311	CDC7	T121	V119A	119	Missense	proximal	-2	no	72.728	70.235	PhosphoSitePlus;EPSD	COSMIC	65.097	Down-regulation
Other_CDC7_CDC7_ST	P19338	NCL	O00311	CDC7	T121	P122L	122	Missense	proximal	1	no	72.728	51.149	PhosphoSitePlus;EPSD	COSMIC	65.097	Loss
Other_CDC7_CDC7_ST	P19338	NCL	O00311	CDC7	S206	D204A	204	Missense	proximal	-2	no	77.704	77.091	EPSD	COSMIC;CCLE	65.097	Down-regulation
Other_CDC7_CDC7_ST	P19338	NCL	O00311	CDC7	S458	G456R	456	Missense	proximal	-2	no	70.617	69.587	EPSD	COSMIC	65.097	Down-regulation
Other_CDC7_CDC7_ST	P19338	NCL	O00311	CDC7	S458	G456L	456	Missense	proximal	-2	no	70.617	70.178	EPSD	COSMIC	65.097	Down-regulation
Other_CDC7_CDC7_ST	P19338	NCL	O00311	CDC7	S532	A536T	536	Missense	distal	4	no	75.509	75.849	EPSD	COSMIC	65.097	Up-regulation
Other_CDC7_CDC7_ST	P19338	NCL	O00311	CDC7	S591	V596I	596	Missense	distal	5	no	77.786	76.541	EPSD	COSMIC	65.097	Down-regulation
Other_CDC7_CDC7_ST	P19338	NCL	O00311	CDC7	S591	G594D	594	Missense	distal	3	no	77.786	78.011	EPSD	COSMIC	65.097	Up-regulation
Other_CDC7_CDC7_ST	P55081	MFAP1	O00311	CDC7	S94	R87W	87	Missense	distal	-7	no	63.830	68.979	EPSD	COSMIC	65.097	Gain
Other_CDC7_CDC7_ST	P55081	MFAP1	O00311	CDC7	S179	E177K	177	Missense	proximal	-2	no	71.787	72.523	EPSD	COSMIC	65.097	Up-regulation
Other_CDC7_CDC7_ST	P55081	MFAP1	O00311	CDC7	S401	G407V	407	Missense	distal	6	no	73.140	72.975	EPSD	COSMIC	65.097	Down-regulation
Other_CDC7_CDC7_ST	P55081	MFAP1	O00311	CDC7	S401	L394F	394	Missense	distal	-7	no	73.140	71.045	EPSD	COSMIC	65.097	Down-regulation
Other_CDC7_CDC7_ST	P55081	MFAP1	O00311	CDC7	S401	D396N	396	Missense	distal	-5	no	73.140	74.603	EPSD	COSMIC	65.097	Up-regulation
Other_CDC7_CDC7_ST	P49736	MCM2	O00311	CDC7	S26	R33W	33	Missense	distal	7	no	74.298	75.024	EPSD	COSMIC	65.097	Up-regulation
Other_CDC7_CDC7_ST	P49736	MCM2	O00311	CDC7	S27	R33W	33	Missense	distal	6	no	82.312	82.089	EPSD;PhosphoSitePlus	COSMIC	65.097	Down-regulation
Other_CDC7_CDC7_ST	P49736	MCM2	O00311	CDC7	S27	R34H	34	Missense	distal	7	no	82.312	82.808	EPSD;PhosphoSitePlus	COSMIC	65.097	Up-regulation
Other_CDC7_CDC7_ST	P49736	MCM2	O00311	CDC7	S31	R33W	33	Missense	proximal	2	no	76.100	72.157	EPSD;PhosphoSitePlus	COSMIC	65.097	Down-regulation
Other_CDC7_CDC7_ST	P49736	MCM2	O00311	CDC7	S31	R34H	34	Missense	distal	3	no	76.100	75.792	EPSD;PhosphoSitePlus	COSMIC	65.097	Down-regulation
Other_CDC7_CDC7_ST	P49736	MCM2	O00311	CDC7	S40	R33W	33	Missense	distal	-7	no	80.370	85.520	EPSD;PhosphoSitePlus	COSMIC	65.097	Up-regulation
Other_CDC7_CDC7_ST	P49736	MCM2	O00311	CDC7	S40	T39I	39	Missense	proximal	-1	no	80.370	79.152	EPSD;PhosphoSitePlus	COSMIC;GDSC	65.097	Down-regulation
Other_CDC7_CDC7_ST	P49736	MCM2	O00311	CDC7	S40	R34H	34	Missense	distal	-6	no	80.370	82.460	EPSD;PhosphoSitePlus	COSMIC	65.097	Up-regulation
Other_CDC7_CDC7_ST	P49736	MCM2	O00311	CDC7	S41	T39I	39	Missense	proximal	-2	no	87.051	86.016	EPSD;PhosphoSitePlus	COSMIC;GDSC	65.097	Down-regulation
Other_CDC7_CDC7_ST	P49736	MCM2	O00311	CDC7	S41	R34H	34	Missense	distal	-7	no	87.051	89.225	EPSD;PhosphoSitePlus	COSMIC	65.097	Up-regulation
Other_CDC7_CDC7_ST	P49736	MCM2	O00311	CDC7	S53	F49C	49	Missense	distal	-4	no	80.927	79.573	EPSD;PhosphoSitePlus	COSMIC	65.097	Down-regulation
Other_CDC7_CDC7_ST	P49736	MCM2	O00311	CDC7	S53	E54V	54	Missense	proximal	1	no	80.927	65.387	EPSD;PhosphoSitePlus	COSMIC	65.097	Down-regulation
Other_CDC7_CDC7_ST	P49736	MCM2	O00311	CDC7	T59	E54V	54	Missense	distal	-5	no	65.895	62.003	EPSD	COSMIC	65.097	Loss
Other_CDC7_CDC7_ST	P49736	MCM2	O00311	CDC7	S108	E104K	104	Missense	distal	-4	no	77.445	77.158	EPSD;PhosphoSitePlus	COSMIC	65.097	Down-regulation
Other_CDC7_CDC7_ST	P49736	MCM2	O00311	CDC7	S108	R115W	115	Missense	distal	7	no	77.445	78.171	EPSD;PhosphoSitePlus	COSMIC	65.097	Up-regulation
Other_CDC7_CDC7_ST	P49736	MCM2	O00311	CDC7	S108	S108R	108	Missense	central	0	yes	77.445	0.000	EPSD;PhosphoSitePlus	COSMIC	65.097	Loss
Other_CDC7_CDC7_ST	P49736	MCM2	O00311	CDC7	S108	V102I	102	Missense	distal	-6	no	77.445	75.123	EPSD;PhosphoSitePlus	COSMIC	65.097	Down-regulation
Other_CDC7_CDC7_ST	P49736	MCM2	O00311	CDC7	S108	A112T	112	Missense	distal	4	no	77.445	77.785	EPSD;PhosphoSitePlus	COSMIC;GDSC;CCLE	65.097	Up-regulation
Other_CDC7_CDC7_ST	P49736	MCM2	O00311	CDC7	S139	R132P	132	Missense	distal	-7	no	81.331	81.622	EPSD;PhosphoSitePlus	COSMIC	65.097	Up-regulation
Other_CDC7_CDC7_ST	P49736	MCM2	O00311	CDC7	S139	R146C	146	Missense	distal	7	no	81.331	81.347	EPSD;PhosphoSitePlus	COSMIC	65.097	Up-regulation
Other_CDC7_CDC7_ST	P49736	MCM2	O00311	CDC7	S220	R227H	227	Missense	distal	7	no	79.669	80.165	EPSD;PhosphoSitePlus	COSMIC;GDSC;CCLE	65.097	Up-regulation
Other_CDC7_CDC7_ST	P49736	MCM2	O00311	CDC7	S220	R218C	218	Missense	proximal	-2	no	79.669	80.032	EPSD;PhosphoSitePlus	COSMIC;GDSC;CCLE	65.097	Up-regulation
Other_CDC7_CDC7_ST	P49736	MCM2	O00311	CDC7	S566	R567M	567	Missense	proximal	1	no	66.076	53.076	EPSD	COSMIC;GDSC;CCLE	65.097	Loss
Other_CDC7_CDC7_ST	P49736	MCM2	O00311	CDC7	S566	A573T	573	Missense	distal	7	no	66.076	64.997	EPSD	COSMIC	65.097	Loss
Other_CDC7_CDC7_ST	P49736	MCM2	O00311	CDC7	S759	S754F	754	Missense	distal	-5	no	70.139	71.148	EPSD	COSMIC	65.097	Up-regulation
Other_CDC7_CDC7_ST	P49736	MCM2	O00311	CDC7	S759	T763M	763	Missense	distal	4	no	70.139	68.116	EPSD	COSMIC	65.097	Down-regulation
Other_CDC7_CDC7_ST	P49736	MCM2	O00311	CDC7	S759	A756V	756	Missense	distal	-3	no	70.139	70.211	EPSD	COSMIC;GDSC	65.097	Up-regulation
Other_CDC7_CDC7_ST	P49736	MCM2	O00311	CDC7	S759	H766N	766	Missense	distal	7	no	70.139	68.328	EPSD	COSMIC	65.097	Down-regulation
Other_CDC7_CDC7_ST	O00311	CDC7	O00311	CDC7	S16	Q18K	18	Missense	proximal	2	no	70.888	67.980	EPSD	COSMIC	65.097	Down-regulation
Other_CDC7_CDC7_ST	O00311	CDC7	O00311	CDC7	S239	S239R	239	Missense	central	0	yes	73.820	0.000	EPSD;PhosphoSitePlus	COSMIC;GDSC;CCLE	65.097	Loss
Other_CDC7_CDC7_ST	O00311	CDC7	O00311	CDC7	S239	G233V	233	Missense	distal	-6	no	73.820	73.317	EPSD;PhosphoSitePlus	COSMIC	65.097	Down-regulation
Other_CDC7_CDC7_ST	O00311	CDC7	O00311	CDC7	S239	N234H	234	Missense	distal	-5	no	73.820	63.756	EPSD;PhosphoSitePlus	COSMIC;CCLE	65.097	Loss
Other_CDC7_CDC7_ST	O00311	CDC7	O00311	CDC7	S239	T232P	232	Missense	distal	-7	no	73.820	74.420	EPSD;PhosphoSitePlus	COSMIC	65.097	Up-regulation
Other_CDC7_CDC7_ST	O00311	CDC7	O00311	CDC7	S277	R284G	284	Missense	distal	7	no	89.579	88.579	EPSD;PhosphoSitePlus	COSMIC	65.097	Down-regulation
Other_CDC7_CDC7_ST	O00311	CDC7	O00311	CDC7	S277	E275K	275	Missense	proximal	-2	no	89.579	90.315	EPSD;PhosphoSitePlus	COSMIC	65.097	Up-regulation
Other_CDC7_CDC7_ST	O00311	CDC7	O00311	CDC7	S277	G276V	276	Missense	proximal	-1	no	89.579	87.078	EPSD;PhosphoSitePlus	COSMIC	65.097	Down-regulation
Other_CDC7_CDC7_ST	O00311	CDC7	O00311	CDC7	S277	R284C	284	Missense	distal	7	no	89.579	89.595	EPSD;PhosphoSitePlus	COSMIC;GDSC;CCLE	65.097	Up-regulation
Other_CDC7_CDC7_ST	O00311	CDC7	O00311	CDC7	S285	R284G	284	Missense	proximal	-1	no	76.028	76.250	EPSD;PhosphoSitePlus	COSMIC	65.097	Up-regulation
Other_CDC7_CDC7_ST	O00311	CDC7	O00311	CDC7	S285	R284C	284	Missense	proximal	-1	no	76.028	74.010	EPSD;PhosphoSitePlus	COSMIC;GDSC;CCLE	65.097	Down-regulation
Other_CDC7_CDC7_ST	O00311	CDC7	O00311	CDC7	S296	I294M	294	Missense	proximal	-2	no	79.325	79.259	EPSD;PhosphoSitePlus	COSMIC	65.097	Down-regulation
Other_CDC7_CDC7_ST	O00311	CDC7	O00311	CDC7	S297	I294M	294	Missense	distal	-3	no	77.322	77.337	EPSD;PhosphoSitePlus	COSMIC	65.097	Up-regulation
Other_CDC7_CDC7_ST	O00311	CDC7	O00311	CDC7	S490	D494N	494	Missense	distal	4	no	66.904	67.248	EPSD	COSMIC	65.097	Up-regulation
Other_CDC7_CDC7_ST	Q9HAW4	CLSPN	O00311	CDC7	S67	A74V	74	Missense	distal	7	no	86.013	86.804	EPSD;PhosphoSitePlus	COSMIC;GDSC;CCLE	65.097	Up-regulation
Other_CDC7_CDC7_ST	Q9HAW4	CLSPN	O00311	CDC7	S67	D66N	66	Missense	proximal	-1	no	86.013	84.554	EPSD;PhosphoSitePlus	COSMIC	65.097	Down-regulation
Other_CDC7_CDC7_ST	Q9HAW4	CLSPN	O00311	CDC7	S83	E90V	90	Missense	distal	7	no	66.323	68.209	EPSD	COSMIC	65.097	Up-regulation
Other_CDC7_CDC7_ST	Q9HAW4	CLSPN	O00311	CDC7	S205	S205R	205	Missense	central	0	yes	65.611	0.000	EPSD	COSMIC	65.097	Loss
Other_CDC7_CDC7_ST	Q9HAW4	CLSPN	O00311	CDC7	S205	P201T	201	Missense	distal	-4	no	65.611	65.910	EPSD	COSMIC	65.097	Up-regulation
Other_CDC7_CDC7_ST	Q9HAW4	CLSPN	O00311	CDC7	S341	S337F	337	Missense	distal	-4	no	66.744	68.014	EPSD	COSMIC	65.097	Up-regulation
Other_CDC7_CDC7_ST	Q9HAW4	CLSPN	O00311	CDC7	S341	I347V	347	Missense	distal	6	no	66.744	66.417	EPSD	COSMIC	65.097	Down-regulation
Other_CDC7_CDC7_ST	Q9HAW4	CLSPN	O00311	CDC7	S425	V427M	427	Missense	proximal	2	no	66.555	69.098	EPSD	COSMIC	65.097	Up-regulation
Other_CDC7_CDC7_ST	Q9HAW4	CLSPN	O00311	CDC7	S704	G702D	702	Missense	proximal	-2	no	79.769	78.578	EPSD;PhosphoSitePlus	COSMIC	65.097	Down-regulation
Other_CDC7_CDC7_ST	Q9HAW4	CLSPN	O00311	CDC7	S704	E698D	698	Missense	distal	-6	no	79.769	78.058	EPSD;PhosphoSitePlus	COSMIC	65.097	Down-regulation
Other_CDC7_CDC7_ST	Q9HAW4	CLSPN	O00311	CDC7	S704	G707C	707	Missense	distal	3	no	79.769	79.702	EPSD;PhosphoSitePlus	COSMIC	65.097	Down-regulation
Other_CDC7_CDC7_ST	Q9HAW4	CLSPN	O00311	CDC7	S721	L727R	727	Missense	distal	6	no	79.382	79.389	EPSD;PhosphoSitePlus	COSMIC	65.097	Up-regulation
Other_CDC7_CDC7_ST	Q9HAW4	CLSPN	O00311	CDC7	S731	M735I	735	Missense	distal	4	no	68.625	68.946	EPSD	COSMIC	65.097	Up-regulation
Other_CDC7_CDC7_ST	Q9HAW4	CLSPN	O00311	CDC7	S731	L727R	727	Missense	distal	-4	no	68.625	68.263	EPSD	COSMIC	65.097	Down-regulation
Other_CDC7_CDC7_ST	Q9HAW4	CLSPN	O00311	CDC7	S744	S744F	744	Missense	central	0	yes	76.867	0.000	EPSD;PhosphoSitePlus	COSMIC	65.097	Loss
Other_CDC7_CDC7_ST	Q9HAW4	CLSPN	O00311	CDC7	T746	S744F	744	Missense	proximal	-2	no	69.867	70.607	EPSD	COSMIC	65.097	Up-regulation
Other_CDC7_CDC7_ST	Q9HAW4	CLSPN	O00311	CDC7	T746	Q753H	753	Missense	distal	7	no	69.867	72.336	EPSD	COSMIC;CCLE	65.097	Up-regulation
Other_CDC7_CDC7_ST	Q9HAW4	CLSPN	O00311	CDC7	S774	K768M	768	Missense	distal	-6	no	63.636	66.122	EPSD	COSMIC	65.097	Gain
Other_CDC7_CDC7_ST	Q9HAW4	CLSPN	O00311	CDC7	S808	G804E	804	Missense	distal	-4	no	69.471	68.201	EPSD	COSMIC	65.097	Down-regulation
Other_CDC7_CDC7_ST	Q9HAW4	CLSPN	O00311	CDC7	S808	S808F	808	Missense	central	0	yes	69.471	0.000	EPSD	COSMIC	65.097	Loss
Other_CDC7_CDC7_ST	Q9HAW4	CLSPN	O00311	CDC7	S968	K966R	966	Missense	proximal	-2	no	69.915	69.666	EPSD	COSMIC	65.097	Down-regulation
Other_CDC7_CDC7_ST	Q9HAW4	CLSPN	O00311	CDC7	S968	M970I	970	Missense	proximal	2	no	69.915	70.719	EPSD	COSMIC	65.097	Up-regulation
Other_CDC7_CDC7_ST	Q9HAW4	CLSPN	O00311	CDC7	S968	S969N	969	Missense	proximal	1	no	69.915	54.189	EPSD	COSMIC	65.097	Loss
Other_CDC7_CDC7_ST	Q9HAW4	CLSPN	O00311	CDC7	S1012	D1019N	1019	Missense	distal	7	no	66.878	66.221	EPSD	COSMIC	65.097	Down-regulation
Other_CDC7_CDC7_ST	Q9HAW4	CLSPN	O00311	CDC7	S1012	D1011H	1011	Missense	proximal	-1	no	66.878	65.613	EPSD	COSMIC	65.097	Down-regulation
Other_CDC7_CDC7_ST	Q9HAW4	CLSPN	O00311	CDC7	S1012	D1013Y	1013	Missense	proximal	1	no	66.878	33.592	EPSD	COSMIC	65.097	Loss
Other_CDC7_CDC7_ST	Q9HAW4	CLSPN	O00311	CDC7	S1096	Q1095P	1095	Missense	proximal	-1	no	79.421	76.571	EPSD	COSMIC	65.097	Down-regulation
Other_CDC7_CDC7_ST	Q9HAW4	CLSPN	O00311	CDC7	S1096	H1102R	1102	Missense	distal	6	no	79.421	79.594	EPSD	COSMIC	65.097	Up-regulation
Other_CDC7_CDC7_ST	Q9HAW4	CLSPN	O00311	CDC7	S1096	M1103T	1103	Missense	distal	7	no	79.421	76.655	EPSD	COSMIC	65.097	Down-regulation
Other_CDC7_CDC7_ST	Q9HAW4	CLSPN	O00311	CDC7	S1129	G1133W	1133	Missense	distal	4	no	85.366	84.442	PhosphoSitePlus;EPSD	COSMIC	65.097	Down-regulation
Other_CDC7_CDC7_ST	Q9HAW4	CLSPN	O00311	CDC7	S1129	P1132L	1132	Missense	distal	3	no	85.366	85.465	PhosphoSitePlus;EPSD	COSMIC	65.097	Up-regulation
Other_CDC7_CDC7_ST	Q9HAW4	CLSPN	O00311	CDC7	S1147	M1149I	1149	Missense	proximal	2	no	74.085	74.890	EPSD;PhosphoSitePlus	COSMIC	65.097	Up-regulation
Other_CDC7_CDC7_ST	Q9HAW4	CLSPN	O00311	CDC7	S1156	D1155E	1155	Missense	proximal	-1	no	63.539	66.276	EPSD	COSMIC	65.097	Gain
Other_CDC7_CDC7_ST	Q9HAW4	CLSPN	O00311	CDC7	T1161	D1155E	1155	Missense	distal	-6	no	80.216	81.928	EPSD	COSMIC	65.097	Up-regulation
Other_CDC7_CDC7_ST	Q9HAW4	CLSPN	O00311	CDC7	S1168	R1171H	1171	Missense	distal	3	no	77.281	76.974	EPSD	COSMIC	65.097	Down-regulation
Other_CDC7_CDC7_ST	Q9HAW4	CLSPN	O00311	CDC7	S1310	P1309R	1309	Missense	proximal	-1	no	64.398	66.964	EPSD	COSMIC	65.097	Gain
Other_CDC7_CDC7_ST	Q9HAW4	CLSPN	O00311	CDC7	S1314	P1315L	1315	Missense	proximal	1	no	69.667	48.088	EPSD	COSMIC	65.097	Loss
Other_CDC7_CDC7_ST	Q9HAW4	CLSPN	O00311	CDC7	S1314	P1309R	1309	Missense	distal	-5	no	69.667	68.956	EPSD	COSMIC	65.097	Down-regulation
Other_CDC7_CDC7_ST	Q9HAW4	CLSPN	O00311	CDC7	S1327	D1323Y	1323	Missense	distal	-4	no	63.646	66.221	EPSD	COSMIC	65.097	Gain
Other_CDC7_CDC7_ST	Q8TEA8	DTD1	O00311	CDC7	S205	R207W	207	Missense	proximal	2	no	67.939	63.996	EPSD;PhosphoSitePlus	COSMIC;GDSC;CCLE	65.097	Loss
Other_CDC7_CDC7_ST	Q8TEA8	DTD1	O00311	CDC7	S205	D202Y	202	Missense	distal	-3	no	67.939	68.176	EPSD;PhosphoSitePlus	COSMIC;GDSC;CCLE	65.097	Up-regulation
Other_CDC7_CDC7_ST	Q8TEA8	DTD1	O00311	CDC7	S205	R207Q	207	Missense	proximal	2	no	67.939	68.180	EPSD;PhosphoSitePlus	COSMIC	65.097	Up-regulation
Other_CDC7_CDC7_ST	P11388	TOP2A	O00311	CDC7	S802	M809V	809	Missense	distal	7	no	70.984	70.087	EPSD	COSMIC	65.097	Down-regulation
Other_CDC7_CDC7_ST	P11388	TOP2A	O00311	CDC7	S1045	A1046P	1046	Missense	proximal	1	no	55.532	75.204	EPSD	COSMIC	65.097	Gain
Other_CDC7_CDC7_ST	P11388	TOP2A	O00311	CDC7	S1106	K1110E	1110	Missense	distal	4	no	69.678	70.094	EPSD	COSMIC;GDSC	65.097	Up-regulation
Other_CDC7_CDC7_ST	P11388	TOP2A	O00311	CDC7	S1213	Q1206H	1206	Missense	distal	-7	no	78.221	84.097	EPSD;PhosphoSitePlus	COSMIC;GDSC;CCLE	65.097	Up-regulation
Other_CDC7_CDC7_ST	P11388	TOP2A	O00311	CDC7	S1213	Q1206K	1206	Missense	distal	-7	no	78.221	79.197	EPSD;PhosphoSitePlus	COSMIC	65.097	Up-regulation
Other_CDC7_CDC7_ST	P11388	TOP2A	O00311	CDC7	S1213	P1214S	1214	Missense	proximal	1	no	78.221	73.910	EPSD;PhosphoSitePlus	COSMIC	65.097	Down-regulation
Other_CDC7_CDC7_ST	P11388	TOP2A	O00311	CDC7	S1295	K1289E	1289	Missense	distal	-6	no	64.691	65.784	EPSD	COSMIC	65.097	Gain
Other_CDC7_CDC7_ST	P11388	TOP2A	O00311	CDC7	S1297	P1293L	1293	Missense	distal	-4	no	73.176	74.245	EPSD	COSMIC	65.097	Up-regulation
Other_CDC7_CDC7_ST	P11388	TOP2A	O00311	CDC7	S1297	D1304G	1304	Missense	distal	7	no	73.176	72.833	EPSD	COSMIC	65.097	Down-regulation
Other_CDC7_CDC7_ST	P11388	TOP2A	O00311	CDC7	S1303	D1304G	1304	Missense	proximal	1	no	77.940	61.825	EPSD	COSMIC	65.097	Loss
Other_CDC7_CDC7_ST	P11388	TOP2A	O00311	CDC7	S1377	D1383N	1383	Missense	distal	6	no	66.952	66.764	EPSD	COSMIC	65.097	Down-regulation
Other_CDC7_CDC7_ST	P11388	TOP2A	O00311	CDC7	S1391	V1388L	1388	Missense	distal	-3	no	69.016	68.929	EPSD	COSMIC	65.097	Down-regulation
Other_CDC7_CDC7_ST	P11388	TOP2A	O00311	CDC7	S1423	S1425F	1425	Missense	proximal	2	no	70.745	64.351	EPSD	COSMIC;GDSC;CCLE	65.097	Loss
Other_CDC7_CDC7_ST	P11388	TOP2A	O00311	CDC7	S1423	S1423I	1423	Missense	central	0	yes	70.745	0.000	EPSD	COSMIC	65.097	Loss
Other_CDC7_CDC7_ST	P11388	TOP2A	O00311	CDC7	S1426	S1425F	1425	Missense	proximal	-1	no	65.166	61.361	EPSD	COSMIC;GDSC;CCLE	65.097	Loss
Other_CDC7_CDC7_ST	P11388	TOP2A	O00311	CDC7	S1426	S1423I	1423	Missense	distal	-3	no	65.166	65.129	EPSD	COSMIC	65.097	Down-regulation
Other_CDC7_CDC7_ST	P11388	TOP2A	O00311	CDC7	S1471	F1478I	1478	Missense	distal	7	no	71.859	70.073	EPSD	COSMIC	65.097	Down-regulation
Other_CDC7_CDC7_ST	P11388	TOP2A	O00311	CDC7	S1471	R1464H	1464	Missense	distal	-7	no	71.859	74.033	EPSD	COSMIC	65.097	Up-regulation
Other_CDC7_CDC7_ST	P11388	TOP2A	O00311	CDC7	S1474	F1478I	1478	Missense	distal	4	no	73.997	74.360	EPSD	COSMIC	65.097	Up-regulation
Other_CDC7_CDC7_ST	P11388	TOP2A	O00311	CDC7	S1488	K1489E	1489	Missense	proximal	1	no	45.464	67.273	EPSD	COSMIC;GDSC;CCLE	65.097	Gain
Other_CDC7_CDC7_ST	Q9UBU7	DBF4	O00311	CDC7	S259	M261V	261	Missense	proximal	2	no	82.872	80.330	EPSD	COSMIC	65.097	Down-regulation
Other_CDC7_CDC7_ST	Q9UBU7	DBF4	O00311	CDC7	S259	Q262R	262	Missense	distal	3	no	82.872	82.657	EPSD	COSMIC	65.097	Down-regulation
Other_CDC7_CDC7_ST	Q9UBU7	DBF4	O00311	CDC7	T273	V267F	267	Missense	distal	-6	no	80.590	78.843	EPSD;PhosphoSitePlus	COSMIC	65.097	Down-regulation
Other_CDC7_CDC7_ST	Q9UBU7	DBF4	O00311	CDC7	T273	L269Q	269	Missense	distal	-4	no	80.590	80.489	EPSD;PhosphoSitePlus	COSMIC	65.097	Down-regulation
Other_CDC7_CDC7_ST	Q9UBU7	DBF4	O00311	CDC7	T281	L287S	287	Missense	distal	6	no	71.885	71.884	EPSD;PhosphoSitePlus	COSMIC	65.097	Down-regulation
Other_CDC7_CDC7_ST	Q9UBU7	DBF4	O00311	CDC7	T281	I283L	283	Missense	proximal	2	no	71.885	69.435	EPSD;PhosphoSitePlus	COSMIC	65.097	Down-regulation
Other_CDC7_CDC7_ST	Q9UBU7	DBF4	O00311	CDC7	S359	S357F	357	Missense	proximal	-2	no	83.320	84.059	EPSD	COSMIC	65.097	Up-regulation
Other_CDC7_CDC7_ST	Q9UBU7	DBF4	O00311	CDC7	S508	P504S	504	Missense	distal	-4	no	71.827	72.494	EPSD	COSMIC	65.097	Up-regulation
Other_CDC7_CDC7_ST	P06748	NPM1	O00311	CDC7	S125	S125L	125	Missense	central	0	yes	79.518	0.000	EPSD	COSMIC	65.097	Loss
Other_CDC7_CDC7_ST	P06748	NPM1	O00311	CDC7	S125	E129Q	129	Missense	distal	4	no	79.518	79.421	EPSD	COSMIC	65.097	Down-regulation
Other_CDC7_CDC7_ST	P06748	NPM1	O00311	CDC7	S125	D127N	127	Missense	proximal	2	no	79.518	77.308	EPSD	COSMIC	65.097	Down-regulation
Other_CDC7_CDC7_ST	P06748	NPM1	O00311	CDC7	T199	P200S	200	Missense	proximal	1	no	76.935	72.624	EPSD;PhosphoSitePlus	COSMIC	65.097	Down-regulation
Other_CDC7_CDC7_ST	P06748	NPM1	O00311	CDC7	T199	S195F	195	Missense	distal	-4	no	76.935	78.205	EPSD;PhosphoSitePlus	COSMIC	65.097	Up-regulation
Other_CDC7_CDC7_ST	P06748	NPM1	O00311	CDC7	S218	G224R	224	Missense	distal	6	no	67.510	67.623	EPSD	COSMIC	65.097	Up-regulation
Other_CDC7_CDC7_ST	P06748	NPM1	O00311	CDC7	S254	I255V	255	Missense	proximal	1	no	75.517	73.871	EPSD	COSMIC	65.097	Down-regulation
Other_CDC7_CDC7_ST	P06748	NPM1	O00311	CDC7	S254	L261F	261	Missense	distal	7	no	75.517	75.185	EPSD	COSMIC	65.097	Down-regulation
Other_CDC7_CDC7_ST	P06748	NPM1	O00311	CDC7	S254	S260C	260	Missense	distal	6	no	75.517	75.423	EPSD	COSMIC	65.097	Down-regulation
Other_CDC7_CDC7_ST	P06748	NPM1	O00311	CDC7	S254	A249G	249	Missense	distal	-5	no	75.517	70.522	EPSD	COSMIC	65.097	Down-regulation
Other_CDC7_CDC7_ST	O75475	PSIP1	O00311	CDC7	S62	F59C	59	Missense	distal	-3	no	70.397	70.428	EPSD	COSMIC;GDSC;CCLE	65.097	Up-regulation
Other_CDC7_CDC7_ST	O75475	PSIP1	O00311	CDC7	S62	I58L	58	Missense	distal	-4	no	70.397	69.939	EPSD	COSMIC	65.097	Down-regulation
Other_CDC7_CDC7_ST	O75475	PSIP1	O00311	CDC7	S62	D57N	57	Missense	distal	-5	no	70.397	71.859	EPSD	COSMIC	65.097	Up-regulation
Other_CDC7_CDC7_ST	O75475	PSIP1	O00311	CDC7	S94	F92I	92	Missense	proximal	-2	no	68.045	67.794	EPSD	COSMIC	65.097	Down-regulation
Other_CDC7_CDC7_ST	Q9NS91	RAD18	O00311	CDC7	S99	S103T	103	Missense	distal	4	no	74.952	76.080	EPSD	COSMIC	65.097	Up-regulation
Other_CDC7_CDC7_ST	Q9NS91	RAD18	O00311	CDC7	S108	S103T	103	Missense	distal	-5	no	61.763	67.109	EPSD	COSMIC	65.097	Gain
Other_CDC7_CDC7_ST	Q9NS91	RAD18	O00311	CDC7	S158	P165R	165	Missense	distal	7	no	79.534	78.418	EPSD	COSMIC	65.097	Down-regulation
Other_CDC7_CDC7_ST	Q9NS91	RAD18	O00311	CDC7	S158	K151I	151	Missense	distal	-7	no	79.534	81.356	EPSD	COSMIC	65.097	Up-regulation
Other_CDC7_CDC7_ST	Q9NS91	RAD18	O00311	CDC7	S434	E429A	429	Missense	distal	-5	no	75.630	75.270	PhosphoSitePlus	COSMIC	65.097	Down-regulation
CMGC_MAPK_JNK_MAPK8_ST	Q01844	EWSR1	P45983-2	MAPK8	T79	T81S	81	Missense	proximal	2	no	7.669	7.665	PhosphoSitePlus	COSMIC	2.638	Down-regulation
CMGC_MAPK_JNK_MAPK8_ST	Q01844	EWSR1	P45983-2	MAPK8	T79	T75A	75	Missense	distal	-4	no	7.669	7.705	PhosphoSitePlus	COSMIC	2.638	Up-regulation
CMGC_MAPK_JNK_MAPK8_ST	Q01844	EWSR1	P45983-2	MAPK8	T79	P83H	83	Missense	distal	4	no	7.669	7.366	PhosphoSitePlus	COSMIC	2.638	Down-regulation
CMGC_MAPK_JNK_MAPK8_ST	Q01844	EWSR1	P45983-2	MAPK8	T79	T78I	78	Missense	proximal	-1	no	7.669	7.656	PhosphoSitePlus	COSMIC	2.638	Down-regulation
CMGC_MAPK_JNK_MAPK8_ST	Q01844	EWSR1	P45983-2	MAPK8	S274	M275I	275	Missense	proximal	1	no	1.036	3.022	EPSD	COSMIC	2.638	Gain
CMGC_MAPK_JNK_MAPK8_ST	Q01844	EWSR1	P45983-2	MAPK8	T422	P421S	421	Missense	proximal	-1	no	2.707	2.717	EPSD	COSMIC	2.638	Up-regulation
CMGC_GSK_GSK3B_ST	Q13131	PRKAA1	P49841	GSK3B	S356	F351L	351	Missense	distal	-5	no	10.303	9.853	EPSD	COSMIC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	Q13131	PRKAA1	P49841	GSK3B	S356	A354T	354	Missense	proximal	-2	no	10.303	10.665	EPSD	COSMIC	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	Q13131	PRKAA1	P49841	GSK3B	S356	D350N	350	Missense	distal	-6	no	10.303	10.326	EPSD	COSMIC	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	Q13131	PRKAA1	P49841	GSK3B	T482	A484D	484	Missense	proximal	2	no	6.344	6.428	EPSD	COSMIC	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	Q13131	PRKAA1	P49841	GSK3B	S486	A484D	484	Missense	proximal	-2	no	8.478	8.797	EPSD;PhosphoSitePlus	COSMIC	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	Q13131	PRKAA1	P49841	GSK3B	T490	V497A	497	Missense	distal	7	no	11.524	11.446	PhosphoSitePlus;EPSD	COSMIC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	Q13131	PRKAA1	P49841	GSK3B	T490	A484D	484	Missense	distal	-6	no	11.524	11.488	PhosphoSitePlus;EPSD	COSMIC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	Q13131	PRKAA1	P49841	GSK3B	S520	S524F	524	Missense	distal	4	no	8.064	4.450	EPSD	COSMIC	6.007	Loss
CMGC_GSK_GSK3B_ST	Q13131	PRKAA1	P49841	GSK3B	S524	S531F	531	Missense	distal	7	no	5.999	6.077	EPSD	COSMIC	6.007	Gain
CMGC_GSK_GSK3B_ST	Q13131	PRKAA1	P49841	GSK3B	T526	S524F	524	Missense	proximal	-2	no	6.927	6.596	EPSD	COSMIC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	Q13131	PRKAA1	P49841	GSK3B	T526	S531F	531	Missense	distal	5	no	6.927	6.260	EPSD	COSMIC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	Q13131	PRKAA1	P49841	GSK3B	S527	S524F	524	Missense	distal	-3	no	7.544	7.611	EPSD	COSMIC	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	Q13131	PRKAA1	P49841	GSK3B	S527	S531F	531	Missense	distal	4	no	7.544	3.930	EPSD	COSMIC	6.007	Loss
CMGC_GSK_GSK3B_ST	Q13131	PRKAA1	P49841	GSK3B	S531	S524F	524	Missense	distal	-7	no	7.665	7.675	EPSD	COSMIC	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	Q13131	PRKAA1	P49841	GSK3B	S531	S531F	531	Missense	central	0	yes	7.665	0.000	EPSD	COSMIC	6.007	Loss
CMGC_GSK_GSK3B_ST	Q13131	PRKAA1	P49841	GSK3B	T536	S531F	531	Missense	distal	-5	no	5.479	6.039	EPSD	COSMIC	6.007	Gain
CMGC_GSK_GSK3B_ST	P11388	TOP2A	P49841	GSK3B	S452	E454D	454	Missense	proximal	2	no	6.040	6.219	EPSD	COSMIC	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	P11388	TOP2A	P49841	GSK3B	S452	I458M	458	Missense	distal	6	no	6.040	6.035	EPSD	COSMIC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	P11388	TOP2A	P49841	GSK3B	S802	M809V	809	Missense	distal	7	no	7.426	7.483	EPSD	COSMIC	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	P11388	TOP2A	P49841	GSK3B	T808	M809V	809	Missense	proximal	1	no	5.481	6.077	EPSD	COSMIC	6.007	Gain
CMGC_GSK_GSK3B_ST	P11388	TOP2A	P49841	GSK3B	T950	T947I	947	Missense	distal	-3	no	6.650	6.738	EPSD	COSMIC	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	P11388	TOP2A	P49841	GSK3B	T950	T947A	947	Missense	distal	-3	no	6.650	6.646	EPSD	COSMIC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	P11388	TOP2A	P49841	GSK3B	T950	T950A	950	Missense	central	0	yes	6.650	0.000	EPSD	COSMIC	6.007	Loss
CMGC_GSK_GSK3B_ST	P11388	TOP2A	P49841	GSK3B	S1045	A1046P	1046	Missense	proximal	1	no	2.467	6.199	EPSD	COSMIC	6.007	Gain
CMGC_GSK_GSK3B_ST	P11388	TOP2A	P49841	GSK3B	S1115	K1110E	1110	Missense	distal	-5	no	6.522	6.753	EPSD	COSMIC;GDSC	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	P11388	TOP2A	P49841	GSK3B	S1213	Q1206H	1206	Missense	distal	-7	no	7.648	7.651	EPSD	COSMIC;GDSC;CCLE	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	P11388	TOP2A	P49841	GSK3B	S1213	Q1206K	1206	Missense	distal	-7	no	7.648	7.655	EPSD	COSMIC	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	P11388	TOP2A	P49841	GSK3B	S1213	P1214S	1214	Missense	proximal	1	no	7.648	3.803	EPSD	COSMIC	6.007	Loss
CMGC_GSK_GSK3B_ST	P11388	TOP2A	P49841	GSK3B	S1247	E1242K	1242	Missense	distal	-5	no	7.143	6.913	EPSD	COSMIC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	P11388	TOP2A	P49841	GSK3B	S1299	P1293L	1293	Missense	distal	-6	no	7.051	7.029	EPSD	COSMIC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	P11388	TOP2A	P49841	GSK3B	S1299	D1304G	1304	Missense	distal	5	no	7.051	6.987	EPSD	COSMIC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	P11388	TOP2A	P49841	GSK3B	S1387	D1383N	1383	Missense	distal	-4	no	6.530	5.833	EPSD	COSMIC	6.007	Loss
CMGC_GSK_GSK3B_ST	P11388	TOP2A	P49841	GSK3B	S1387	V1388L	1388	Missense	proximal	1	no	6.530	6.660	EPSD	COSMIC	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	P11388	TOP2A	P49841	GSK3B	S1393	V1388L	1388	Missense	distal	-5	no	7.378	6.907	EPSD	COSMIC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	P36956	SREBF1	P49841	GSK3B	T426	E420K	420	Missense	distal	-6	no	10.176	10.175	EPSD;PhosphoSitePlus	COSMIC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	P36956	SREBF1	P49841	GSK3B	T426	D423G	423	Missense	distal	-3	no	10.176	10.126	EPSD;PhosphoSitePlus	COSMIC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	P36956	SREBF1	P49841	GSK3B	S430	D423G	423	Missense	distal	-7	no	8.704	8.700	EPSD;PhosphoSitePlus	COSMIC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	P36956	SREBF1	P49841	GSK3B	S434	P440H	440	Missense	distal	6	no	9.403	9.391	PhosphoSitePlus;EPSD	COSMIC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	P36956	SREBF1	P49841	GSK3B	S439	L443F	443	Missense	distal	4	no	8.192	7.296	EPSD	COSMIC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	P36956	SREBF1	P49841	GSK3B	S439	P440H	440	Missense	proximal	1	no	8.192	4.492	EPSD	COSMIC	6.007	Loss
CMGC_GSK_GSK3B_ST	P36956	SREBF1	P49841	GSK3B	S453	G454D	454	Missense	proximal	1	no	9.040	9.130	EPSD	COSMIC	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	P36956	SREBF1	P49841	GSK3B	S453	P459H	459	Missense	distal	6	no	9.040	9.028	EPSD	COSMIC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	P36956	SREBF1	P49841	GSK3B	S453	G451S	451	Missense	proximal	-2	no	9.040	9.157	EPSD	COSMIC;CCLE	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	P36956	SREBF1	P49841	GSK3B	S453	S448R	448	Missense	distal	-5	no	9.040	9.737	EPSD	COSMIC;CCLE	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	P36956	SREBF1	P49841	GSK3B	S457	G454D	454	Missense	distal	-3	no	7.730	7.781	EPSD	COSMIC	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	P36956	SREBF1	P49841	GSK3B	S457	P459H	459	Missense	proximal	2	no	7.730	6.961	EPSD	COSMIC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	P36956	SREBF1	P49841	GSK3B	S457	G451S	451	Missense	distal	-6	no	7.730	7.714	EPSD	COSMIC;CCLE	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	P36956	SREBF1	P49841	GSK3B	S461	G454D	454	Missense	distal	-7	no	8.348	8.352	EPSD	COSMIC	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	P36956	SREBF1	P49841	GSK3B	S461	P459H	459	Missense	proximal	-2	no	8.348	7.986	EPSD	COSMIC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	P36956	SREBF1	P49841	GSK3B	S524	G531A	531	Missense	distal	7	no	5.814	6.142	EPSD	COSMIC	6.007	Gain
CMGC_GSK_GSK3B_ST	P36956	SREBF1	P49841	GSK3B	S1049	T1051I	1051	Missense	proximal	2	no	6.389	6.323	EPSD	COSMIC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	P36956	SREBF1	P49841	GSK3B	S1049	A1046V	1046	Missense	distal	-3	no	6.389	6.535	EPSD	COSMIC	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	P36956	SREBF1	P49841	GSK3B	S1049	G1047W	1047	Missense	proximal	-2	no	6.389	6.597	EPSD	COSMIC	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	P10636	MAPT	P49841	GSK3B	S68	E62K	62	Missense	distal	-6	no	6.933	6.932	EPSD	COSMIC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	P10636	MAPT	P49841	GSK3B	T69	E62K	62	Missense	distal	-7	no	6.768	6.757	EPSD	COSMIC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	P10636	MAPT	P49841	GSK3B	T111	I108V	108	Missense	distal	-3	no	8.413	8.467	EPSD	COSMIC	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	P10636	MAPT	P49841	GSK3B	T111	G107R	107	Missense	distal	-4	no	8.413	7.654	EPSD	COSMIC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	P10636	MAPT	P49841	GSK3B	T167	P160Q	160	Missense	distal	-7	no	7.072	7.089	EPSD	COSMIC	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	P10636	MAPT	P49841	GSK3B	T167	A166V	166	Missense	proximal	-1	no	7.072	7.275	EPSD	COSMIC;CCLE	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	P10636	MAPT	P49841	GSK3B	T167	E165K	165	Missense	proximal	-2	no	7.072	7.041	EPSD	COSMIC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	P10636	MAPT	P49841	GSK3B	T167	P160S	160	Missense	distal	-7	no	7.072	7.074	EPSD	COSMIC	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	P10636	MAPT	P49841	GSK3B	T167	G172V	172	Missense	distal	5	no	7.072	6.529	EPSD	COSMIC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	P10636	MAPT	P49841	GSK3B	S171	P175S	175	Missense	distal	4	no	6.238	9.210	EPSD	COSMIC	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	P10636	MAPT	P49841	GSK3B	S171	A166V	166	Missense	distal	-5	no	6.238	6.541	EPSD	COSMIC;CCLE	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	P10636	MAPT	P49841	GSK3B	S171	E176G	176	Missense	distal	5	no	6.238	5.972	EPSD	COSMIC	6.007	Loss
CMGC_GSK_GSK3B_ST	P10636	MAPT	P49841	GSK3B	S171	D177G	177	Missense	distal	6	no	6.238	6.243	EPSD	COSMIC	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	P10636	MAPT	P49841	GSK3B	S171	E165K	165	Missense	distal	-6	no	6.238	6.237	EPSD	COSMIC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	P10636	MAPT	P49841	GSK3B	S171	G172V	172	Missense	proximal	1	no	6.238	6.442	EPSD	COSMIC	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	P10636	MAPT	P49841	GSK3B	S228	S227N	227	Missense	proximal	-1	no	11.620	11.682	EPSD	COSMIC	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	P10636	MAPT	P49841	GSK3B	S228	S227I	227	Missense	proximal	-1	no	11.620	11.470	EPSD	COSMIC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	P10636	MAPT	P49841	GSK3B	S228	E226K	226	Missense	proximal	-2	no	11.620	11.589	EPSD	COSMIC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	P10636	MAPT	P49841	GSK3B	S228	Q230R	230	Missense	proximal	2	no	11.620	11.416	EPSD	COSMIC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	P10636	MAPT	P49841	GSK3B	S228	P233S	233	Missense	distal	5	no	11.620	10.666	EPSD	COSMIC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	P10636	MAPT	P49841	GSK3B	S228	D225E	225	Missense	distal	-3	no	11.620	11.587	EPSD	COSMIC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	P10636	MAPT	P49841	GSK3B	S228	S227G	227	Missense	proximal	-1	no	11.620	11.627	EPSD	COSMIC	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	P10636	MAPT	P49841	GSK3B	S228	S235L	235	Missense	distal	7	no	11.620	11.606	EPSD	COSMIC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	P10636	MAPT	P49841	GSK3B	S232	S227N	227	Missense	distal	-5	no	6.264	5.972	EPSD	COSMIC	6.007	Loss
CMGC_GSK_GSK3B_ST	P10636	MAPT	P49841	GSK3B	S232	S227I	227	Missense	distal	-5	no	6.264	6.737	EPSD	COSMIC	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	P10636	MAPT	P49841	GSK3B	S232	A237T	237	Missense	distal	5	no	6.264	6.317	EPSD	COSMIC	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	P10636	MAPT	P49841	GSK3B	S232	E226K	226	Missense	distal	-6	no	6.264	6.263	EPSD	COSMIC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	P10636	MAPT	P49841	GSK3B	S232	Q230R	230	Missense	proximal	-2	no	6.264	6.194	EPSD	COSMIC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	P10636	MAPT	P49841	GSK3B	S232	S238P	238	Missense	distal	6	no	6.264	6.266	EPSD	COSMIC	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	P10636	MAPT	P49841	GSK3B	S232	P233S	233	Missense	proximal	1	no	6.264	2.420	EPSD	COSMIC	6.007	Loss
CMGC_GSK_GSK3B_ST	P10636	MAPT	P49841	GSK3B	S232	S238F	238	Missense	distal	6	no	6.264	6.252	EPSD	COSMIC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	P10636	MAPT	P49841	GSK3B	S232	D225E	225	Missense	distal	-7	no	6.264	6.294	EPSD	COSMIC	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	P10636	MAPT	P49841	GSK3B	S232	S227G	227	Missense	distal	-5	no	6.264	6.731	EPSD	COSMIC	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	P10636	MAPT	P49841	GSK3B	S232	S235L	235	Missense	distal	3	no	6.264	5.964	EPSD	COSMIC	6.007	Loss
CMGC_GSK_GSK3B_ST	P10636	MAPT	P49841	GSK3B	S238	A237T	237	Missense	proximal	-1	no	7.281	7.360	EPSD	COSMIC	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	P10636	MAPT	P49841	GSK3B	S238	A240S	240	Missense	proximal	2	no	7.281	7.273	EPSD	COSMIC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	P10636	MAPT	P49841	GSK3B	S238	D242N	242	Missense	distal	4	no	7.281	6.094	EPSD	COSMIC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	P10636	MAPT	P49841	GSK3B	S238	R244W	244	Missense	distal	6	no	7.281	7.270	EPSD	COSMIC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	P10636	MAPT	P49841	GSK3B	S238	S238P	238	Missense	central	0	yes	7.281	0.000	EPSD	COSMIC	6.007	Loss
CMGC_GSK_GSK3B_ST	P10636	MAPT	P49841	GSK3B	S238	P233S	233	Missense	distal	-5	no	7.281	7.438	EPSD	COSMIC	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	P10636	MAPT	P49841	GSK3B	S238	S238F	238	Missense	central	0	yes	7.281	0.000	EPSD	COSMIC	6.007	Loss
CMGC_GSK_GSK3B_ST	P10636	MAPT	P49841	GSK3B	S238	G243D	243	Missense	distal	5	no	7.281	7.344	EPSD	COSMIC	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	P10636	MAPT	P49841	GSK3B	S238	S235L	235	Missense	distal	-3	no	7.281	7.290	EPSD	COSMIC	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	P10636	MAPT	P49841	GSK3B	S396	R398C	398	Missense	proximal	2	no	6.124	5.613	EPSD;PhosphoSitePlus	COSMIC	6.007	Loss
CMGC_GSK_GSK3B_ST	P10636	MAPT	P49841	GSK3B	S396	S396F	396	Missense	central	0	yes	6.124	0.000	EPSD;PhosphoSitePlus	COSMIC	6.007	Loss
CMGC_GSK_GSK3B_ST	P10636	MAPT	P49841	GSK3B	S396	D389N	389	Missense	distal	-7	no	6.124	6.127	EPSD;PhosphoSitePlus	COSMIC;GDSC;CCLE	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	P10636	MAPT	P49841	GSK3B	T416	L410F	410	Missense	distal	-6	no	9.074	9.022	EPSD	COSMIC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	P10636	MAPT	P49841	GSK3B	T416	P412S	412	Missense	distal	-4	no	9.074	9.638	EPSD	COSMIC	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	P10636	MAPT	P49841	GSK3B	S438	S443Y	443	Missense	distal	5	no	6.877	5.878	EPSD	COSMIC	6.007	Loss
CMGC_GSK_GSK3B_ST	P10636	MAPT	P49841	GSK3B	S447	S443Y	443	Missense	distal	-4	no	9.392	8.591	EPSD	COSMIC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	P10636	MAPT	P49841	GSK3B	S447	S447P	447	Missense	central	0	yes	9.392	0.000	EPSD	COSMIC	6.007	Loss
CMGC_GSK_GSK3B_ST	P10636	MAPT	P49841	GSK3B	S447	R448Q	448	Missense	proximal	1	no	9.392	8.443	EPSD	COSMIC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	P10636	MAPT	P49841	GSK3B	T470	T466M	466	Missense	distal	-4	no	6.449	5.725	EPSD	COSMIC;GDSC;CCLE	6.007	Loss
CMGC_GSK_GSK3B_ST	P10636	MAPT	P49841	GSK3B	T470	K467T	467	Missense	distal	-3	no	6.449	6.451	EPSD	COSMIC	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	P10636	MAPT	P49841	GSK3B	T470	P477L	477	Missense	distal	7	no	6.449	6.498	EPSD	COSMIC	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	P10636	MAPT	P49841	GSK3B	T470	P477S	477	Missense	distal	7	no	6.449	6.513	EPSD	COSMIC	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	P10636	MAPT	P49841	GSK3B	T498	K491R	491	Missense	distal	-7	no	9.030	9.027	EPSD	COSMIC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	P10636	MAPT	P49841	GSK3B	T498	A495T	495	Missense	distal	-3	no	9.030	9.034	EPSD	COSMIC	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	P10636	MAPT	P49841	GSK3B	T498	P493L	493	Missense	distal	-5	no	9.030	9.295	EPSD	COSMIC	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	P10636	MAPT	P49841	GSK3B	S508	P506S	506	Missense	proximal	-2	no	6.264	6.008	EPSD	COSMIC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	P10636	MAPT	P49841	GSK3B	S508	R511C	511	Missense	distal	3	no	6.264	6.420	EPSD	COSMIC;CCLE	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	P10636	MAPT	P49841	GSK3B	S508	G509V	509	Missense	proximal	1	no	6.264	6.467	EPSD	COSMIC	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	P10636	MAPT	P49841	GSK3B	S508	P506L	506	Missense	proximal	-2	no	6.264	5.934	EPSD	COSMIC	6.007	Loss
CMGC_GSK_GSK3B_ST	P10636	MAPT	P49841	GSK3B	S512	P506S	506	Missense	distal	-6	no	6.640	6.620	EPSD	COSMIC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	P10636	MAPT	P49841	GSK3B	S512	G518V	518	Missense	distal	6	no	6.640	6.634	EPSD	COSMIC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	P10636	MAPT	P49841	GSK3B	S512	R511C	511	Missense	proximal	-1	no	6.640	6.742	EPSD	COSMIC;CCLE	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	P10636	MAPT	P49841	GSK3B	S512	G509V	509	Missense	distal	-3	no	6.640	6.812	EPSD	COSMIC	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	P10636	MAPT	P49841	GSK3B	S512	P506L	506	Missense	distal	-6	no	6.640	6.618	EPSD	COSMIC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	P10636	MAPT	P49841	GSK3B	S515	G521V	521	Missense	distal	6	no	7.219	7.212	EPSD	COSMIC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	P10636	MAPT	P49841	GSK3B	S515	G518V	518	Missense	distal	3	no	7.219	6.967	EPSD	COSMIC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	P10636	MAPT	P49841	GSK3B	S515	R511C	511	Missense	distal	-4	no	7.219	6.291	EPSD	COSMIC;CCLE	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	P10636	MAPT	P49841	GSK3B	S515	G509V	509	Missense	distal	-6	no	7.219	7.135	EPSD	COSMIC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	P10636	MAPT	P49841	GSK3B	S516	G521V	521	Missense	distal	5	no	7.391	6.847	EPSD	COSMIC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	P10636	MAPT	P49841	GSK3B	S516	G518V	518	Missense	proximal	2	no	7.391	7.380	EPSD	COSMIC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	P10636	MAPT	P49841	GSK3B	S516	R511C	511	Missense	distal	-5	no	7.391	7.213	EPSD	COSMIC;CCLE	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	P10636	MAPT	P49841	GSK3B	S516	G509V	509	Missense	distal	-7	no	7.391	7.415	EPSD	COSMIC	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	P10636	MAPT	P49841	GSK3B	S519	G521V	521	Missense	proximal	2	no	7.994	7.983	EPSD	COSMIC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	P10636	MAPT	P49841	GSK3B	S519	R526H	526	Missense	distal	7	no	7.994	8.182	EPSD	COSMIC	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	P10636	MAPT	P49841	GSK3B	S519	G518V	518	Missense	proximal	-1	no	7.994	8.035	EPSD	COSMIC	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	P10636	MAPT	P49841	GSK3B	T522	G521V	521	Missense	proximal	-1	no	6.333	6.375	EPSD	COSMIC	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	P10636	MAPT	P49841	GSK3B	T522	R526H	526	Missense	distal	4	no	6.333	5.615	EPSD	COSMIC	6.007	Loss
CMGC_GSK_GSK3B_ST	P10636	MAPT	P49841	GSK3B	T522	G518V	518	Missense	distal	-4	no	6.333	5.528	EPSD	COSMIC	6.007	Loss
CMGC_GSK_GSK3B_ST	P10636	MAPT	P49841	GSK3B	T522	R528S	528	Missense	distal	6	no	6.333	6.338	EPSD	COSMIC	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	P10636	MAPT	P49841	GSK3B	S525	G521V	521	Missense	distal	-4	no	8.083	7.277	EPSD	COSMIC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	P10636	MAPT	P49841	GSK3B	S525	R526H	526	Missense	proximal	1	no	8.083	6.702	EPSD	COSMIC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	P10636	MAPT	P49841	GSK3B	S525	G518V	518	Missense	distal	-7	no	8.083	8.106	EPSD	COSMIC	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	P10636	MAPT	P49841	GSK3B	S525	R528S	528	Missense	distal	3	no	8.083	8.454	EPSD	COSMIC	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	P10636	MAPT	P49841	GSK3B	S525	P530S	530	Missense	distal	5	no	8.083	7.129	EPSD	COSMIC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	P10636	MAPT	P49841	GSK3B	S527	G521V	521	Missense	distal	-6	no	7.147	7.063	EPSD	COSMIC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	P10636	MAPT	P49841	GSK3B	S527	R526H	526	Missense	proximal	-1	no	7.147	7.232	EPSD	COSMIC	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	P10636	MAPT	P49841	GSK3B	S527	R528S	528	Missense	proximal	1	no	7.147	5.622	EPSD	COSMIC	6.007	Loss
CMGC_GSK_GSK3B_ST	P10636	MAPT	P49841	GSK3B	S527	P530S	530	Missense	distal	3	no	7.147	7.129	EPSD	COSMIC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	P10636	MAPT	P49841	GSK3B	T529	R526H	526	Missense	distal	-3	no	6.762	6.705	EPSD	COSMIC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	P10636	MAPT	P49841	GSK3B	T529	R528S	528	Missense	proximal	-1	no	6.762	6.899	EPSD	COSMIC	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	P10636	MAPT	P49841	GSK3B	T529	P530S	530	Missense	proximal	1	no	6.762	2.917	EPSD	COSMIC	6.007	Loss
CMGC_GSK_GSK3B_ST	P10636	MAPT	P49841	GSK3B	T529	P536H	536	Missense	distal	7	no	6.762	7.451	EPSD	COSMIC	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	P10636	MAPT	P49841	GSK3B	T529	P535Q	535	Missense	distal	6	no	6.762	6.756	EPSD	COSMIC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	P10636	MAPT	P49841	GSK3B	S531	R526H	526	Missense	distal	-5	no	8.534	8.003	EPSD	COSMIC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	P10636	MAPT	P49841	GSK3B	S531	R528S	528	Missense	distal	-3	no	8.534	8.365	EPSD	COSMIC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	P10636	MAPT	P49841	GSK3B	S531	P530S	530	Missense	proximal	-1	no	8.534	8.477	EPSD	COSMIC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	P10636	MAPT	P49841	GSK3B	S531	P536H	536	Missense	distal	5	no	8.534	6.907	EPSD	COSMIC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	P10636	MAPT	P49841	GSK3B	S531	P535Q	535	Missense	distal	4	no	8.534	7.942	EPSD	COSMIC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	P10636	MAPT	P49841	GSK3B	T534	R528S	528	Missense	distal	-6	no	7.148	7.205	EPSD	COSMIC	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	P10636	MAPT	P49841	GSK3B	T534	P530S	530	Missense	distal	-4	no	7.148	7.711	EPSD	COSMIC	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	P10636	MAPT	P49841	GSK3B	T534	P536H	536	Missense	proximal	2	no	7.148	6.379	EPSD	COSMIC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	P10636	MAPT	P49841	GSK3B	T534	P535Q	535	Missense	proximal	1	no	7.148	3.880	EPSD	COSMIC	6.007	Loss
CMGC_GSK_GSK3B_ST	P10636	MAPT	P49841	GSK3B	T534	E539Q	539	Missense	distal	5	no	7.148	6.817	EPSD	COSMIC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	P10636	MAPT	P49841	GSK3B	T548	P550S	550	Missense	proximal	2	no	10.508	10.064	EPSD	COSMIC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	P10636	MAPT	P49841	GSK3B	T548	P553R	553	Missense	distal	5	no	10.508	9.870	EPSD	COSMIC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	P10636	MAPT	P49841	GSK3B	T548	P553L	553	Missense	distal	5	no	10.508	9.227	EPSD	COSMIC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	P10636	MAPT	P49841	GSK3B	T548	P549L	549	Missense	proximal	1	no	10.508	7.648	EPSD	COSMIC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	P10636	MAPT	P49841	GSK3B	T548	S555F	555	Missense	distal	7	no	10.508	10.586	EPSD	COSMIC	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	P10636	MAPT	P49841	GSK3B	T548	P553Q	553	Missense	distal	5	no	10.508	9.532	EPSD	COSMIC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	P10636	MAPT	P49841	GSK3B	S552	P550S	550	Missense	proximal	-2	no	7.533	7.276	EPSD	COSMIC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	P10636	MAPT	P49841	GSK3B	S552	R559C	559	Missense	distal	7	no	7.533	7.487	EPSD	COSMIC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	P10636	MAPT	P49841	GSK3B	S552	P553R	553	Missense	proximal	1	no	7.533	5.213	EPSD	COSMIC	6.007	Loss
CMGC_GSK_GSK3B_ST	P10636	MAPT	P49841	GSK3B	S552	P553L	553	Missense	proximal	1	no	7.533	4.672	EPSD	COSMIC	6.007	Loss
CMGC_GSK_GSK3B_ST	P10636	MAPT	P49841	GSK3B	S552	P549L	549	Missense	distal	-3	no	7.533	7.659	EPSD	COSMIC	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	P10636	MAPT	P49841	GSK3B	S552	S555F	555	Missense	distal	3	no	7.533	7.322	EPSD	COSMIC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	P10636	MAPT	P49841	GSK3B	S552	P553Q	553	Missense	proximal	1	no	7.533	4.264	EPSD	COSMIC	6.007	Loss
CMGC_GSK_GSK3B_ST	P10636	MAPT	P49841	GSK3B	S554	P550S	550	Missense	distal	-4	no	5.560	6.124	EPSD	COSMIC	6.007	Gain
CMGC_GSK_GSK3B_ST	P10636	MAPT	P49841	GSK3B	S558	V565M	565	Missense	distal	7	no	6.704	6.647	EPSD	COSMIC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	P10636	MAPT	P49841	GSK3B	S558	R559C	559	Missense	proximal	1	no	6.704	4.701	EPSD	COSMIC	6.007	Loss
CMGC_GSK_GSK3B_ST	P10636	MAPT	P49841	GSK3B	S558	P553R	553	Missense	distal	-5	no	6.704	7.558	EPSD	COSMIC	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	P10636	MAPT	P49841	GSK3B	S558	P553L	553	Missense	distal	-5	no	6.704	6.970	EPSD	COSMIC	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	P10636	MAPT	P49841	GSK3B	S558	S555F	555	Missense	distal	-3	no	6.704	6.771	EPSD	COSMIC	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	P10636	MAPT	P49841	GSK3B	S558	P553Q	553	Missense	distal	-5	no	6.704	7.004	EPSD	COSMIC	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	P10636	MAPT	P49841	GSK3B	S575	T580N	580	Missense	distal	5	no	7.105	6.807	EPSD	COSMIC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	P10636	MAPT	P49841	GSK3B	S575	G578S	578	Missense	distal	3	no	7.105	7.061	EPSD	COSMIC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	P10636	MAPT	P49841	GSK3B	S575	K571E	571	Missense	distal	-4	no	7.105	7.373	EPSD	COSMIC	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	P10636	MAPT	P49841	GSK3B	S575	P568S	568	Missense	distal	-7	no	7.105	7.107	EPSD	COSMIC	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	P10636	MAPT	P49841	GSK3B	S606	N613D	613	Missense	distal	7	no	7.048	6.980	EPSD	COSMIC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	P10636	MAPT	P49841	GSK3B	S606	S602G	602	Missense	distal	-4	no	7.048	6.620	EPSD	COSMIC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	P10636	MAPT	P49841	GSK3B	S606	C608W	608	Missense	proximal	2	no	7.048	7.129	EPSD	COSMIC	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	P10636	MAPT	P49841	GSK3B	S606	S610L	610	Missense	distal	4	no	7.048	4.330	EPSD	COSMIC	6.007	Loss
CMGC_GSK_GSK3B_ST	P10636	MAPT	P49841	GSK3B	S606	D600E	600	Missense	distal	-6	no	7.048	7.011	EPSD	COSMIC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	P10636	MAPT	P49841	GSK3B	S637	S633N	633	Missense	distal	-4	no	7.884	6.586	EPSD	COSMIC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	P10636	MAPT	P49841	GSK3B	S637	S633I	633	Missense	distal	-4	no	7.884	5.401	EPSD	COSMIC	6.007	Loss
CMGC_GSK_GSK3B_ST	P10636	MAPT	P49841	GSK3B	S669	S669L	669	Missense	central	0	yes	7.593	0.000	EPSD	COSMIC	6.007	Loss
CMGC_GSK_GSK3B_ST	P10636	MAPT	P49841	GSK3B	S669	R666K	666	Missense	distal	-3	no	7.593	7.448	EPSD	COSMIC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	P10636	MAPT	P49841	GSK3B	S669	D662G	662	Missense	distal	-7	no	7.593	7.588	EPSD	COSMIC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	P10636	MAPT	P49841	GSK3B	S669	S673F	673	Missense	distal	4	no	7.593	3.979	EPSD	COSMIC	6.007	Loss
CMGC_GSK_GSK3B_ST	P10636	MAPT	P49841	GSK3B	S669	K670N	670	Missense	proximal	1	no	7.593	5.619	EPSD	COSMIC	6.007	Loss
CMGC_GSK_GSK3B_ST	P10636	MAPT	P49841	GSK3B	S669	K664N	664	Missense	distal	-5	no	7.593	7.101	EPSD	COSMIC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	P10636	MAPT	P49841	GSK3B	S669	L674Q	674	Missense	distal	5	no	7.593	7.897	EPSD	COSMIC	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	P10636	MAPT	P49841	GSK3B	S713	E708D	708	Missense	distal	-5	no	9.598	9.439	EPSD	COSMIC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	P10636	MAPT	P49841	GSK3B	S713	G706R	706	Missense	distal	-7	no	9.598	9.618	EPSD	COSMIC	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	P10636	MAPT	P49841	GSK3B	S713	V710M	710	Missense	distal	-3	no	9.598	9.402	EPSD	COSMIC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	P10636	MAPT	P49841	GSK3B	S713	E708K	708	Missense	distal	-5	no	9.598	9.367	EPSD	COSMIC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	P10636	MAPT	P49841	GSK3B	S713	V710A	710	Missense	distal	-3	no	9.598	9.451	EPSD	COSMIC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	P10636	MAPT	P49841	GSK3B	S717	R723W	723	Missense	distal	6	no	9.078	9.067	EPSD	COSMIC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	P10636	MAPT	P49841	GSK3B	S717	V710A	710	Missense	distal	-7	no	9.078	9.079	EPSD	COSMIC	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	P10636	MAPT	P49841	GSK3B	S721	R723W	723	Missense	proximal	2	no	9.949	9.519	EPSD	COSMIC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	P10636	MAPT	P49841	GSK3B	S721	V728M	728	Missense	distal	7	no	9.949	9.892	EPSD	COSMIC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	P10636	MAPT	P49841	GSK3B	S721	V728A	728	Missense	distal	7	no	9.949	9.871	EPSD	COSMIC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	P10636	MAPT	P49841	GSK3B	S739	G732S	732	Missense	distal	-7	no	8.627	8.630	EPSD	COSMIC	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	P10636	MAPT	P49841	GSK3B	S739	D735N	735	Missense	distal	-4	no	8.627	7.930	EPSD	COSMIC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	P10636	MAPT	P49841	GSK3B	S739	G732C	732	Missense	distal	-7	no	8.627	8.652	EPSD	COSMIC	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	P10636	MAPT	P49841	GSK3B	S739	T744M	744	Missense	distal	5	no	8.627	8.511	EPSD	COSMIC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	P10636	MAPT	P49841	GSK3B	S739	A743T	743	Missense	distal	4	no	8.627	10.170	EPSD	COSMIC	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	Q8N122	RPTOR	P49841	GSK3B	S696	E689K	689	Missense	distal	-7	no	7.052	7.040	EPSD	COSMIC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	Q8N122	RPTOR	P49841	GSK3B	S696	S696Y	696	Missense	central	0	yes	7.052	0.000	EPSD	COSMIC	6.007	Loss
CMGC_GSK_GSK3B_ST	Q8N122	RPTOR	P49841	GSK3B	S696	A693T	693	Missense	distal	-3	no	7.052	7.056	EPSD	COSMIC;GDSC;CCLE	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	Q8N122	RPTOR	P49841	GSK3B	S696	G702E	702	Missense	distal	6	no	7.052	7.049	EPSD	COSMIC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	Q8N122	RPTOR	P49841	GSK3B	S696	S696A	696	Missense	central	0	yes	7.052	0.000	EPSD	COSMIC	6.007	Loss
CMGC_GSK_GSK3B_ST	Q8N122	RPTOR	P49841	GSK3B	T706	P712L	712	Missense	distal	6	no	7.306	7.299	EPSD	COSMIC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	Q8N122	RPTOR	P49841	GSK3B	T706	D710N	710	Missense	distal	4	no	7.306	6.119	EPSD	COSMIC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	Q8N122	RPTOR	P49841	GSK3B	T706	R709G	709	Missense	distal	3	no	7.306	7.721	EPSD	COSMIC	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	Q8N122	RPTOR	P49841	GSK3B	T706	G702E	702	Missense	distal	-4	no	7.306	7.137	EPSD	COSMIC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	Q8N122	RPTOR	P49841	GSK3B	S711	R718C	718	Missense	distal	7	no	6.809	6.764	EPSD	COSMIC;CCLE	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	Q8N122	RPTOR	P49841	GSK3B	S711	P712L	712	Missense	proximal	1	no	6.809	3.949	EPSD	COSMIC	6.007	Loss
CMGC_GSK_GSK3B_ST	Q8N122	RPTOR	P49841	GSK3B	S711	P715S	715	Missense	distal	4	no	6.809	9.780	EPSD	COSMIC	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	Q8N122	RPTOR	P49841	GSK3B	S711	D710N	710	Missense	proximal	-1	no	6.809	6.931	EPSD	COSMIC	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	Q8N122	RPTOR	P49841	GSK3B	S711	R709G	709	Missense	proximal	-2	no	6.809	6.807	EPSD	COSMIC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	Q8N122	RPTOR	P49841	GSK3B	T714	R718C	718	Missense	distal	4	no	6.633	3.538	EPSD	COSMIC;CCLE	6.007	Loss
CMGC_GSK_GSK3B_ST	Q8N122	RPTOR	P49841	GSK3B	T714	P712L	712	Missense	proximal	-2	no	6.633	6.302	EPSD	COSMIC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	Q8N122	RPTOR	P49841	GSK3B	T714	P715S	715	Missense	proximal	1	no	6.633	2.788	EPSD	COSMIC	6.007	Loss
CMGC_GSK_GSK3B_ST	Q8N122	RPTOR	P49841	GSK3B	T714	D710N	710	Missense	distal	-4	no	6.633	5.936	EPSD	COSMIC	6.007	Loss
CMGC_GSK_GSK3B_ST	Q8N122	RPTOR	P49841	GSK3B	T714	S719Y	719	Missense	distal	5	no	6.633	5.634	EPSD	COSMIC	6.007	Loss
CMGC_GSK_GSK3B_ST	Q8N122	RPTOR	P49841	GSK3B	T714	S721N	721	Missense	distal	7	no	6.633	6.756	EPSD	COSMIC	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	Q8N122	RPTOR	P49841	GSK3B	T714	V720L	720	Missense	distal	6	no	6.633	6.638	EPSD	COSMIC	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	Q8N122	RPTOR	P49841	GSK3B	T714	R709G	709	Missense	distal	-5	no	6.633	6.402	EPSD	COSMIC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	Q8N122	RPTOR	P49841	GSK3B	S738	S738Y	738	Missense	central	0	yes	6.617	0.000	EPSD	COSMIC	6.007	Loss
CMGC_GSK_GSK3B_ST	Q8N122	RPTOR	P49841	GSK3B	S738	T731A	731	Missense	distal	-7	no	6.617	6.612	EPSD	COSMIC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	Q8N122	RPTOR	P49841	GSK3B	S767	A765T	765	Missense	proximal	-2	no	9.089	9.451	EPSD	COSMIC	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	Q8N122	RPTOR	P49841	GSK3B	S767	S766T	766	Missense	proximal	-1	no	9.089	9.014	EPSD	COSMIC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	Q8N122	RPTOR	P49841	GSK3B	S771	A765T	765	Missense	distal	-6	no	10.004	9.935	EPSD	COSMIC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	Q8N122	RPTOR	P49841	GSK3B	S771	E775Q	775	Missense	distal	4	no	10.004	8.461	EPSD	COSMIC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	Q8N122	RPTOR	P49841	GSK3B	S771	S766T	766	Missense	distal	-5	no	10.004	10.293	EPSD	COSMIC	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	Q8N122	RPTOR	P49841	GSK3B	S794	R789H	789	Missense	distal	-5	no	6.209	5.678	EPSD	COSMIC;GDSC;CCLE	6.007	Loss
CMGC_GSK_GSK3B_ST	Q8N122	RPTOR	P49841	GSK3B	S794	R788C	788	Missense	distal	-6	no	6.209	6.254	EPSD	COSMIC;GDSC;CCLE	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	Q8N122	RPTOR	P49841	GSK3B	S794	R788H	788	Missense	distal	-6	no	6.209	6.232	EPSD	COSMIC	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	Q8N122	RPTOR	P49841	GSK3B	S794	S798F	798	Missense	distal	4	no	6.209	2.594	EPSD	COSMIC	6.007	Loss
CMGC_GSK_GSK3B_ST	Q8N122	RPTOR	P49841	GSK3B	S794	S792F	792	Missense	proximal	-2	no	6.209	5.878	EPSD	COSMIC	6.007	Loss
CMGC_GSK_GSK3B_ST	Q8N122	RPTOR	P49841	GSK3B	S794	A790S	790	Missense	distal	-4	no	6.209	7.368	EPSD	COSMIC	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	Q8N122	RPTOR	P49841	GSK3B	S794	L799H	799	Missense	distal	5	no	6.209	5.862	EPSD	COSMIC	6.007	Loss
CMGC_GSK_GSK3B_ST	Q8N122	RPTOR	P49841	GSK3B	S798	L796I	796	Missense	proximal	-2	no	7.131	7.194	EPSD	COSMIC	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	Q8N122	RPTOR	P49841	GSK3B	S798	S798F	798	Missense	central	0	yes	7.131	0.000	EPSD	COSMIC	6.007	Loss
CMGC_GSK_GSK3B_ST	Q8N122	RPTOR	P49841	GSK3B	S798	S792F	792	Missense	distal	-6	no	7.131	7.077	EPSD	COSMIC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	Q8N122	RPTOR	P49841	GSK3B	S798	L799H	799	Missense	proximal	1	no	7.131	6.291	EPSD	COSMIC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	Q8N122	RPTOR	P49841	GSK3B	S855	P861L	861	Missense	distal	6	no	7.438	7.431	EPSD	COSMIC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	Q8N122	RPTOR	P49841	GSK3B	S855	V850I	850	Missense	distal	-5	no	7.438	7.331	EPSD	COSMIC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	Q8N122	RPTOR	P49841	GSK3B	S855	A862T	862	Missense	distal	7	no	7.438	7.031	EPSD	COSMIC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	Q8N122	RPTOR	P49841	GSK3B	S855	S854A	854	Missense	proximal	-1	no	7.438	7.283	EPSD	COSMIC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	Q8N122	RPTOR	P49841	GSK3B	S859	P861L	861	Missense	proximal	2	no	8.586	8.202	PhosphoSitePlus;EPSD	COSMIC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	Q8N122	RPTOR	P49841	GSK3B	S859	A862T	862	Missense	distal	3	no	8.586	8.890	PhosphoSitePlus;EPSD	COSMIC	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	Q8N122	RPTOR	P49841	GSK3B	S859	S854A	854	Missense	distal	-5	no	8.586	8.863	PhosphoSitePlus;EPSD	COSMIC	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	Q8N122	RPTOR	P49841	GSK3B	S863	K867R	867	Missense	distal	4	no	8.183	8.348	EPSD;PhosphoSitePlus	COSMIC	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	Q8N122	RPTOR	P49841	GSK3B	S863	G868S	868	Missense	distal	5	no	8.183	8.141	EPSD;PhosphoSitePlus	COSMIC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	Q8N122	RPTOR	P49841	GSK3B	S863	P861L	861	Missense	proximal	-2	no	8.183	7.853	EPSD;PhosphoSitePlus	COSMIC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	Q8N122	RPTOR	P49841	GSK3B	S863	V869M	869	Missense	distal	6	no	8.183	8.188	EPSD;PhosphoSitePlus	COSMIC	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	Q8N122	RPTOR	P49841	GSK3B	S863	A862T	862	Missense	proximal	-1	no	8.183	8.263	EPSD;PhosphoSitePlus	COSMIC	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	Q8N122	RPTOR	P49841	GSK3B	S877	A874V	874	Missense	distal	-3	no	10.498	10.644	EPSD;PhosphoSitePlus	COSMIC;GDSC;CCLE	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	Q8N122	RPTOR	P49841	GSK3B	S877	P878S	878	Missense	proximal	1	no	10.498	6.653	EPSD;PhosphoSitePlus	COSMIC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	Q8N122	RPTOR	P49841	GSK3B	S877	P879S	879	Missense	proximal	2	no	10.498	10.054	EPSD;PhosphoSitePlus	COSMIC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	Q8N122	RPTOR	P49841	GSK3B	S877	A880S	880	Missense	distal	3	no	10.498	10.835	EPSD;PhosphoSitePlus	COSMIC	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	Q8N122	RPTOR	P49841	GSK3B	S877	P878L	878	Missense	proximal	1	no	10.498	7.637	EPSD;PhosphoSitePlus	COSMIC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	Q8N122	RPTOR	P49841	GSK3B	S881	A874V	874	Missense	distal	-7	no	7.749	7.748	EPSD	COSMIC;GDSC;CCLE	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	Q8N122	RPTOR	P49841	GSK3B	S881	P878S	878	Missense	distal	-3	no	7.749	7.865	EPSD	COSMIC	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	Q8N122	RPTOR	P49841	GSK3B	S881	P879S	879	Missense	proximal	-2	no	7.749	7.492	EPSD	COSMIC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	Q8N122	RPTOR	P49841	GSK3B	S881	A880S	880	Missense	proximal	-1	no	7.749	7.903	EPSD	COSMIC	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	Q8N122	RPTOR	P49841	GSK3B	S881	P878L	878	Missense	distal	-3	no	7.749	7.875	EPSD	COSMIC	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	Q8N122	RPTOR	P49841	GSK3B	S882	T889A	889	Missense	distal	7	no	6.772	7.178	EPSD	COSMIC	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	Q8N122	RPTOR	P49841	GSK3B	S882	P878S	878	Missense	distal	-4	no	6.772	7.335	EPSD	COSMIC	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	Q8N122	RPTOR	P49841	GSK3B	S882	P879S	879	Missense	distal	-3	no	6.772	6.888	EPSD	COSMIC	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	Q8N122	RPTOR	P49841	GSK3B	S882	A880S	880	Missense	proximal	-2	no	6.772	7.106	EPSD	COSMIC	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	Q8N122	RPTOR	P49841	GSK3B	S882	P878L	878	Missense	distal	-4	no	6.772	5.985	EPSD	COSMIC	6.007	Loss
CMGC_GSK_GSK3B_ST	Q8N122	RPTOR	P49841	GSK3B	T883	P879S	879	Missense	distal	-4	no	5.800	6.364	EPSD	COSMIC	6.007	Gain
CMGC_GSK_GSK3B_ST	Q8N122	RPTOR	P49841	GSK3B	T883	P878L	878	Missense	distal	-5	no	5.800	6.066	EPSD	COSMIC	6.007	Gain
CMGC_GSK_GSK3B_ST	Q8N122	RPTOR	P49841	GSK3B	T917	P924T	924	Missense	distal	7	no	6.035	6.039	EPSD	COSMIC	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	Q8N122	RPTOR	P49841	GSK3B	T917	Y916C	916	Missense	proximal	-1	no	6.035	6.139	EPSD	COSMIC;GDSC;CCLE	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	Q8N122	RPTOR	P49841	GSK3B	T917	P911L	911	Missense	distal	-6	no	6.035	6.012	EPSD	COSMIC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	Q8N122	RPTOR	P49841	GSK3B	T917	G910D	910	Missense	distal	-7	no	6.035	6.040	EPSD	COSMIC	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	Q8N122	RPTOR	P49841	GSK3B	T917	Q922R	922	Missense	distal	5	no	6.035	6.374	EPSD	COSMIC	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	Q13541	EIF4EBP1	P49841	GSK3B	S65	L59Q	59	Missense	distal	-6	no	7.228	7.225	PhosphoSitePlus;EPSD	COSMIC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	Q13541	EIF4EBP1	P49841	GSK3B	S65	M60I	60	Missense	distal	-5	no	7.228	7.399	PhosphoSitePlus;EPSD	COSMIC	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	Q13541	EIF4EBP1	P49841	GSK3B	S65	P72S	72	Missense	distal	7	no	7.228	7.291	PhosphoSitePlus;EPSD	COSMIC	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	Q13541	EIF4EBP1	P49841	GSK3B	S65	R63W	63	Missense	proximal	-2	no	7.228	7.434	PhosphoSitePlus;EPSD	COSMIC	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	Q13541	EIF4EBP1	P49841	GSK3B	T68	P72S	72	Missense	distal	4	no	4.404	7.375	EPSD	COSMIC	6.007	Gain
CMGC_GSK_GSK3B_ST	Q13541	EIF4EBP1	P49841	GSK3B	S83	S85F	85	Missense	proximal	2	no	7.700	7.355	EPSD	COSMIC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	Q13541	EIF4EBP1	P49841	GSK3B	S101	N100H	100	Missense	proximal	-1	no	6.885	6.772	EPSD	COSMIC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	Q13541	EIF4EBP1	P49841	GSK3B	S101	R106L	106	Missense	distal	5	no	6.885	6.242	EPSD	COSMIC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	Q15208	STK38	P49841	GSK3B	S6	S6P	6	Missense	central	0	yes	7.729	0.000	PhosphoSitePlus;EPSD	COSMIC	6.007	Loss
CMGC_GSK_GSK3B_ST	Q15208	STK38	P49841	GSK3B	S6	P8S	8	Missense	proximal	2	no	7.729	7.285	PhosphoSitePlus;EPSD	COSMIC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	Q15208	STK38	P49841	GSK3B	T7	S6P	6	Missense	proximal	-1	no	7.295	7.351	EPSD;PhosphoSitePlus	COSMIC	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	Q15208	STK38	P49841	GSK3B	T7	P8S	8	Missense	proximal	1	no	7.295	3.450	EPSD;PhosphoSitePlus	COSMIC	6.007	Loss
CMGC_GSK_GSK3B_ST	Q15208	STK38	P49841	GSK3B	S281	G284C	284	Missense	distal	3	no	7.111	6.852	EPSD	COSMIC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	P50895	BCAM	P49841	GSK3B	S206	M204K	204	Missense	proximal	-2	no	6.864	7.061	EPSD	COSMIC	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	P50895	BCAM	P49841	GSK3B	S206	E201K	201	Missense	distal	-5	no	6.864	6.634	EPSD	COSMIC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	P50895	BCAM	P49841	GSK3B	S206	T205I	205	Missense	proximal	-1	no	6.864	6.790	EPSD	COSMIC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	P50895	BCAM	P49841	GSK3B	S296	R292W	292	Missense	distal	-4	no	6.134	5.304	EPSD	COSMIC	6.007	Loss
CMGC_GSK_GSK3B_ST	P50895	BCAM	P49841	GSK3B	S296	E300K	300	Missense	distal	4	no	6.134	4.952	EPSD	COSMIC	6.007	Loss
CMGC_GSK_GSK3B_ST	P50895	BCAM	P49841	GSK3B	S447	L450P	450	Missense	distal	3	no	5.869	6.187	EPSD	COSMIC	6.007	Gain
CMGC_GSK_GSK3B_ST	P50895	BCAM	P49841	GSK3B	S541	G538S	538	Missense	distal	-3	no	9.231	9.235	EPSD	COSMIC	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	P50895	BCAM	P49841	GSK3B	S541	V534I	534	Missense	distal	-7	no	9.231	9.238	EPSD	COSMIC	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	P50895	BCAM	P49841	GSK3B	S596	S598L	598	Missense	proximal	2	no	6.700	6.760	PhosphoSitePlus	COSMIC	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	P50895	BCAM	P49841	GSK3B	S596	S596R	596	Missense	central	0	yes	6.700	0.000	PhosphoSitePlus	COSMIC	6.007	Loss
CMGC_GSK_GSK3B_ST	Q9UPN3	MACF1	P49841	GSK3B	S31	G32R	32	Missense	proximal	1	no	6.399	7.273	EPSD	COSMIC	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	Q9UPN3	MACF1	P49841	GSK3B	S31	R27K	27	Missense	distal	-4	no	6.399	6.721	EPSD	COSMIC	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	Q9UPN3	MACF1	P49841	GSK3B	S31	P36L	36	Missense	distal	5	no	6.399	5.119	EPSD	COSMIC	6.007	Loss
CMGC_GSK_GSK3B_ST	Q9UPN3	MACF1	P49841	GSK3B	S35	G32R	32	Missense	distal	-3	no	7.018	7.191	EPSD	COSMIC	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	Q9UPN3	MACF1	P49841	GSK3B	S35	T42I	42	Missense	distal	7	no	7.018	7.413	EPSD	COSMIC	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	Q9UPN3	MACF1	P49841	GSK3B	S35	P36L	36	Missense	proximal	1	no	7.018	4.158	EPSD	COSMIC	6.007	Loss
CMGC_GSK_GSK3B_ST	Q9UPN3	MACF1	P49841	GSK3B	S280	V278M	278	Missense	proximal	-2	no	6.510	6.212	EPSD	COSMIC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	Q9UPN3	MACF1	P49841	GSK3B	T334	I335V	335	Missense	proximal	1	no	6.277	7.167	EPSD	COSMIC	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	Q9UPN3	MACF1	P49841	GSK3B	T334	P328S	328	Missense	distal	-6	no	6.277	6.256	EPSD	COSMIC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	Q9UPN3	MACF1	P49841	GSK3B	T334	I330V	330	Missense	distal	-4	no	6.277	7.526	EPSD	COSMIC	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	Q9UPN3	MACF1	P49841	GSK3B	S559	H558N	558	Missense	proximal	-1	no	6.119	6.232	EPSD	COSMIC	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	Q9UPN3	MACF1	P49841	GSK3B	S559	T557A	557	Missense	proximal	-2	no	6.119	5.757	EPSD	COSMIC;GDSC;CCLE	6.007	Loss
CMGC_GSK_GSK3B_ST	Q9UPN3	MACF1	P49841	GSK3B	S862	S862N	862	Missense	central	0	yes	8.019	0.000	EPSD	COSMIC	6.007	Loss
CMGC_GSK_GSK3B_ST	Q9UPN3	MACF1	P49841	GSK3B	S862	P863L	863	Missense	proximal	1	no	8.019	5.158	EPSD	COSMIC	6.007	Loss
CMGC_GSK_GSK3B_ST	Q9UPN3	MACF1	P49841	GSK3B	S1122	S1122I	1122	Missense	central	0	yes	10.429	0.000	EPSD	COSMIC	6.007	Loss
CMGC_GSK_GSK3B_ST	Q9UPN3	MACF1	P49841	GSK3B	S1127	S1122I	1122	Missense	distal	-5	no	5.782	6.254	EPSD	COSMIC	6.007	Gain
CMGC_GSK_GSK3B_ST	Q9UPN3	MACF1	P49841	GSK3B	S1363	K1370E	1370	Missense	distal	7	no	7.336	7.444	EPSD	COSMIC	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	Q9UPN3	MACF1	P49841	GSK3B	S1367	R1373C	1373	Missense	distal	6	no	8.371	8.362	EPSD	COSMIC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	Q9UPN3	MACF1	P49841	GSK3B	S1367	K1370E	1370	Missense	distal	3	no	8.371	8.478	EPSD	COSMIC	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	Q9UPN3	MACF1	P49841	GSK3B	S1367	R1373P	1373	Missense	distal	6	no	8.371	8.377	EPSD	COSMIC	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	Q9UPN3	MACF1	P49841	GSK3B	S2006	Y2003F	2003	Missense	distal	-3	no	7.218	7.144	EPSD	COSMIC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	Q9UPN3	MACF1	P49841	GSK3B	S2933	K2929E	2929	Missense	distal	-4	no	5.870	6.137	EPSD	COSMIC	6.007	Gain
CMGC_GSK_GSK3B_ST	Q9UPN3	MACF1	P49841	GSK3B	S3016	I3018V	3018	Missense	proximal	2	no	6.795	6.465	EPSD	COSMIC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	Q9UPN3	MACF1	P49841	GSK3B	S3692	R3694C	3694	Missense	proximal	2	no	6.543	6.033	EPSD	COSMIC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	Q9UPN3	MACF1	P49841	GSK3B	S3692	L3691F	3691	Missense	proximal	-1	no	6.543	6.488	EPSD	COSMIC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	Q9UPN3	MACF1	P49841	GSK3B	S3913	S3914L	3914	Missense	proximal	1	no	5.864	6.848	EPSD	COSMIC	6.007	Gain
CMGC_GSK_GSK3B_ST	Q9UPN3	MACF1	P49841	GSK3B	S3913	S3914G	3914	Missense	proximal	1	no	5.864	6.515	EPSD	COSMIC	6.007	Gain
CMGC_GSK_GSK3B_ST	Q9UPN3	MACF1	P49841	GSK3B	S3914	S3914L	3914	Missense	central	0	yes	6.900	0.000	EPSD	COSMIC	6.007	Loss
CMGC_GSK_GSK3B_ST	Q9UPN3	MACF1	P49841	GSK3B	S3914	S3914G	3914	Missense	central	0	yes	6.900	0.000	EPSD	COSMIC	6.007	Loss
CMGC_GSK_GSK3B_ST	Q9UPN3	MACF1	P49841	GSK3B	S3914	G3912S	3912	Missense	proximal	-2	no	6.900	7.018	EPSD	COSMIC	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	Q9UPN3	MACF1	P49841	GSK3B	S3914	T3917I	3917	Missense	distal	3	no	6.900	6.513	EPSD	COSMIC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	Q9UPN3	MACF1	P49841	GSK3B	S3914	P3919L	3919	Missense	distal	5	no	6.900	5.620	EPSD	COSMIC	6.007	Loss
CMGC_GSK_GSK3B_ST	Q9UPN3	MACF1	P49841	GSK3B	S3914	L3918I	3918	Missense	distal	4	no	6.900	6.296	EPSD	COSMIC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	Q9UPN3	MACF1	P49841	GSK3B	S3914	G3911E	3911	Missense	distal	-3	no	6.900	6.918	EPSD	COSMIC	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	Q9UPN3	MACF1	P49841	GSK3B	S3914	S3920F	3920	Missense	distal	6	no	6.900	6.888	EPSD	COSMIC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	Q9UPN3	MACF1	P49841	GSK3B	S3914	S3913I	3913	Missense	proximal	-1	no	6.900	6.751	EPSD	COSMIC;CCLE	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	Q9UPN3	MACF1	P49841	GSK3B	S4141	S4142T	4142	Missense	proximal	1	no	7.276	7.929	EPSD	COSMIC;CCLE	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	Q9UPN3	MACF1	P49841	GSK3B	S4168	R4173Q	4173	Missense	distal	5	no	6.582	6.243	EPSD	COSMIC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	Q9UPN3	MACF1	P49841	GSK3B	S4415	P4414R	4414	Missense	proximal	-1	no	7.201	7.008	EPSD	COSMIC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	Q9UPN3	MACF1	P49841	GSK3B	S4415	S4422C	4422	Missense	distal	7	no	7.201	7.593	EPSD	COSMIC	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	Q9UPN3	MACF1	P49841	GSK3B	S4496	K4489Q	4489	Missense	distal	-7	no	9.264	9.258	EPSD	COSMIC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	Q9UPN3	MACF1	P49841	GSK3B	S4946	S4950C	4950	Missense	distal	4	no	7.048	0.916	EPSD	COSMIC	6.007	Loss
CMGC_GSK_GSK3B_ST	Q9UPN3	MACF1	P49841	GSK3B	S5429	R5433S	5433	Missense	distal	4	no	4.727	7.764	EPSD	COSMIC	6.007	Gain
CMGC_GSK_GSK3B_ST	Q9UPN3	MACF1	P49841	GSK3B	S5588	E5582V	5582	Missense	distal	-6	no	6.548	6.543	EPSD	COSMIC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	Q9UPN3	MACF1	P49841	GSK3B	S5588	V5581E	5581	Missense	distal	-7	no	6.548	6.559	EPSD	COSMIC	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	Q9UPN3	MACF1	P49841	GSK3B	S5592	P5599S	5599	Missense	distal	7	no	8.862	8.925	EPSD	COSMIC	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	Q9UPN3	MACF1	P49841	GSK3B	S5808	L5806F	5806	Missense	proximal	-2	no	8.639	8.382	EPSD	COSMIC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	Q9UPN3	MACF1	P49841	GSK3B	S5912	S5911F	5911	Missense	proximal	-1	no	7.689	7.558	EPSD	COSMIC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	Q9UPN3	MACF1	P49841	GSK3B	S5912	P5918S	5918	Missense	distal	6	no	7.689	7.687	EPSD	COSMIC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	Q9UPN3	MACF1	P49841	GSK3B	S5912	R5915C	5915	Missense	distal	3	no	7.689	7.844	EPSD	COSMIC	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	Q9UPN3	MACF1	P49841	GSK3B	S5912	L5910F	5910	Missense	proximal	-2	no	7.689	7.432	EPSD	COSMIC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	Q9UPN3	MACF1	P49841	GSK3B	S6353	E6347D	6347	Missense	distal	-6	no	6.468	6.505	EPSD	COSMIC	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	Q9UPN3	MACF1	P49841	GSK3B	S6353	E6347K	6347	Missense	distal	-6	no	6.468	6.467	EPSD	COSMIC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	Q9UPN3	MACF1	P49841	GSK3B	S6406	S6410T	6410	Missense	distal	4	no	7.020	6.151	EPSD	COSMIC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	Q9UPN3	MACF1	P49841	GSK3B	S6408	S6410T	6410	Missense	proximal	2	no	7.106	7.232	EPSD	COSMIC	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	Q9UPN3	MACF1	P49841	GSK3B	S6969	P6973S	6973	Missense	distal	4	no	5.439	8.410	EPSD	COSMIC	6.007	Gain
CMGC_GSK_GSK3B_ST	Q9UPN3	MACF1	P49841	GSK3B	T6972	I6978V	6978	Missense	distal	6	no	8.601	8.591	EPSD	COSMIC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	Q9UPN3	MACF1	P49841	GSK3B	T6972	P6977L	6977	Missense	distal	5	no	8.601	7.320	EPSD	COSMIC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	Q9UPN3	MACF1	P49841	GSK3B	T6972	P6973S	6973	Missense	proximal	1	no	8.601	4.756	EPSD	COSMIC	6.007	Loss
CMGC_GSK_GSK3B_ST	Q9UPN3	MACF1	P49841	GSK3B	T6972	P6974L	6974	Missense	proximal	2	no	8.601	8.217	EPSD	COSMIC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	Q9UPN3	MACF1	P49841	GSK3B	T6972	P6977T	6977	Missense	distal	5	no	8.601	7.624	EPSD	COSMIC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	Q9UPN3	MACF1	P49841	GSK3B	T6972	P6977S	6977	Missense	distal	5	no	8.601	7.647	EPSD	COSMIC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	Q9UPN3	MACF1	P49841	GSK3B	T6972	L6968V	6968	Missense	distal	-4	no	8.601	8.717	EPSD	COSMIC	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	Q9UPN3	MACF1	P49841	GSK3B	S7209	A7208T	7208	Missense	proximal	-1	no	6.491	6.571	EPSD	COSMIC	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	Q9UPN3	MACF1	P49841	GSK3B	S7209	I7203T	7203	Missense	distal	-6	no	6.491	6.496	EPSD	COSMIC	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	Q9UPN3	MACF1	P49841	GSK3B	S7209	G7207C	7207	Missense	proximal	-2	no	6.491	6.297	EPSD	COSMIC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	Q9UPN3	MACF1	P49841	GSK3B	T7213	G7219D	7219	Missense	distal	6	no	9.462	9.458	EPSD	COSMIC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	Q9UPN3	MACF1	P49841	GSK3B	T7213	A7208T	7208	Missense	distal	-5	no	9.462	9.473	EPSD	COSMIC	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	Q9UPN3	MACF1	P49841	GSK3B	T7213	G7207C	7207	Missense	distal	-6	no	9.462	9.434	EPSD	COSMIC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	Q9UPN3	MACF1	P49841	GSK3B	S7226	P7231L	7231	Missense	distal	5	no	8.824	7.543	EPSD;PhosphoSitePlus	COSMIC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	Q9UPN3	MACF1	P49841	GSK3B	S7226	G7219D	7219	Missense	distal	-7	no	8.824	8.829	EPSD;PhosphoSitePlus	COSMIC	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	Q9UPN3	MACF1	P49841	GSK3B	S7226	R7221T	7221	Missense	distal	-5	no	8.824	8.416	EPSD;PhosphoSitePlus	COSMIC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	Q9UPN3	MACF1	P49841	GSK3B	S7226	P7231T	7231	Missense	distal	5	no	8.824	7.847	EPSD;PhosphoSitePlus	COSMIC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	Q9UPN3	MACF1	P49841	GSK3B	S7226	P7231A	7231	Missense	distal	5	no	8.824	7.795	EPSD;PhosphoSitePlus	COSMIC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	Q9UPN3	MACF1	P49841	GSK3B	S7230	P7231L	7231	Missense	proximal	1	no	9.895	7.034	EPSD;PhosphoSitePlus	COSMIC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	Q9UPN3	MACF1	P49841	GSK3B	S7230	P7231T	7231	Missense	proximal	1	no	9.895	6.704	EPSD;PhosphoSitePlus	COSMIC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	Q9UPN3	MACF1	P49841	GSK3B	S7230	P7231A	7231	Missense	proximal	1	no	9.895	6.163	EPSD;PhosphoSitePlus	COSMIC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	Q9UPN3	MACF1	P49841	GSK3B	S7230	S7235N	7235	Missense	distal	5	no	9.895	9.574	EPSD;PhosphoSitePlus	COSMIC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	Q9UPN3	MACF1	P49841	GSK3B	S7247	T7254P	7254	Missense	distal	7	no	6.704	6.699	EPSD	COSMIC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	Q9UPN3	MACF1	P49841	GSK3B	S7247	Q7240R	7240	Missense	distal	-7	no	6.704	6.707	EPSD	COSMIC	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	Q9UPN3	MACF1	P49841	GSK3B	S7251	T7254P	7254	Missense	distal	3	no	7.910	7.961	EPSD	COSMIC	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	Q9UPN3	MACF1	P49841	GSK3B	T7254	T7254P	7254	Missense	central	0	yes	6.672	0.000	EPSD	COSMIC	6.007	Loss
CMGC_GSK_GSK3B_ST	Q9UPN3	MACF1	P49841	GSK3B	S7278	R7280Q	7280	Missense	proximal	2	no	5.819	6.023	EPSD	COSMIC	6.007	Gain
CMGC_GSK_GSK3B_ST	Q9UPN3	MACF1	P49841	GSK3B	S7288	P7293L	7293	Missense	distal	5	no	6.117	4.836	EPSD	COSMIC	6.007	Loss
CMGC_GSK_GSK3B_ST	Q9UPN3	MACF1	P49841	GSK3B	S7288	A7294V	7294	Missense	distal	6	no	6.117	6.108	EPSD	COSMIC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	Q9UPN3	MACF1	P49841	GSK3B	S7288	D7286N	7286	Missense	proximal	-2	no	6.117	5.904	EPSD	COSMIC	6.007	Loss
CMGC_GSK_GSK3B_ST	Q9UPN3	MACF1	P49841	GSK3B	S7288	D7286Y	7286	Missense	proximal	-2	no	6.117	5.813	EPSD	COSMIC	6.007	Loss
CMGC_GSK_GSK3B_ST	Q9UPN3	MACF1	P49841	GSK3B	S7288	A7284S	7284	Missense	distal	-4	no	6.117	7.277	EPSD	COSMIC	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	Q9UPN3	MACF1	P49841	GSK3B	S7288	A7284V	7284	Missense	distal	-4	no	6.117	6.043	EPSD	COSMIC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	Q9UPN3	MACF1	P49841	GSK3B	S7291	P7293L	7293	Missense	proximal	2	no	6.910	6.526	EPSD	COSMIC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	Q9UPN3	MACF1	P49841	GSK3B	S7291	A7294V	7294	Missense	distal	3	no	6.910	7.039	EPSD	COSMIC	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	Q9UPN3	MACF1	P49841	GSK3B	S7291	D7286N	7286	Missense	distal	-5	no	6.910	6.346	EPSD	COSMIC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	Q9UPN3	MACF1	P49841	GSK3B	S7291	D7286Y	7286	Missense	distal	-5	no	6.910	7.290	EPSD	COSMIC	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	Q9UPN3	MACF1	P49841	GSK3B	S7291	A7284S	7284	Missense	distal	-7	no	6.910	6.888	EPSD	COSMIC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	Q9UPN3	MACF1	P49841	GSK3B	S7291	A7284V	7284	Missense	distal	-7	no	6.910	6.909	EPSD	COSMIC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	Q9UPN3	MACF1	P49841	GSK3B	S7292	P7293L	7293	Missense	proximal	1	no	11.477	8.616	EPSD	COSMIC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	Q9UPN3	MACF1	P49841	GSK3B	S7292	A7294V	7294	Missense	proximal	2	no	11.477	11.200	EPSD	COSMIC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	Q9UPN3	MACF1	P49841	GSK3B	S7292	D7286N	7286	Missense	distal	-6	no	11.477	11.500	EPSD	COSMIC	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	Q9UPN3	MACF1	P49841	GSK3B	S7292	D7286Y	7286	Missense	distal	-6	no	11.477	11.416	EPSD	COSMIC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	Q9UPN3	MACF1	P49841	GSK3B	S7310	R7311H	7311	Missense	proximal	1	no	8.655	7.275	EPSD;PhosphoSitePlus	COSMIC;CCLE	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	Q9UPN3	MACF1	P49841	GSK3B	S7310	A7309V	7309	Missense	proximal	-1	no	8.655	8.859	EPSD;PhosphoSitePlus	COSMIC	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	Q9UPN3	MACF1	P49841	GSK3B	S7314	R7311H	7311	Missense	distal	-3	no	10.462	10.406	EPSD;PhosphoSitePlus	COSMIC;CCLE	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	Q9UPN3	MACF1	P49841	GSK3B	S7314	G7321R	7321	Missense	distal	7	no	10.462	10.880	EPSD;PhosphoSitePlus	COSMIC	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	Q9UPN3	MACF1	P49841	GSK3B	S7314	G7321W	7321	Missense	distal	7	no	10.462	10.989	EPSD;PhosphoSitePlus	COSMIC	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	Q9UPN3	MACF1	P49841	GSK3B	S7314	A7309V	7309	Missense	distal	-5	no	10.462	10.765	EPSD;PhosphoSitePlus	COSMIC	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	Q9UPN3	MACF1	P49841	GSK3B	S7318	R7311H	7311	Missense	distal	-7	no	8.526	8.525	EPSD;PhosphoSitePlus	COSMIC;CCLE	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	Q9UPN3	MACF1	P49841	GSK3B	S7318	G7321R	7321	Missense	distal	3	no	8.526	8.111	EPSD;PhosphoSitePlus	COSMIC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	Q9UPN3	MACF1	P49841	GSK3B	S7318	G7321W	7321	Missense	distal	3	no	8.526	8.370	EPSD;PhosphoSitePlus	COSMIC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	Q9UPN3	MACF1	P49841	GSK3B	S7322	R7327Q	7327	Missense	distal	5	no	9.022	8.683	EPSD;PhosphoSitePlus	COSMIC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	Q9UPN3	MACF1	P49841	GSK3B	S7322	R7328Q	7328	Missense	distal	6	no	9.022	9.023	EPSD;PhosphoSitePlus	COSMIC	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	Q9UPN3	MACF1	P49841	GSK3B	S7322	G7321R	7321	Missense	proximal	-1	no	9.022	8.878	EPSD;PhosphoSitePlus	COSMIC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	Q9UPN3	MACF1	P49841	GSK3B	S7322	G7321W	7321	Missense	proximal	-1	no	9.022	8.990	EPSD;PhosphoSitePlus	COSMIC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	Q9UPN3	MACF1	P49841	GSK3B	S7322	R7327W	7327	Missense	distal	5	no	9.022	7.721	EPSD;PhosphoSitePlus	COSMIC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	Q9UPN3	MACF1	P49841	GSK3B	S7326	R7327Q	7327	Missense	proximal	1	no	7.358	6.409	EPSD;PhosphoSitePlus	COSMIC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	Q9UPN3	MACF1	P49841	GSK3B	S7326	R7328Q	7328	Missense	proximal	2	no	7.358	7.562	EPSD;PhosphoSitePlus	COSMIC	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	Q9UPN3	MACF1	P49841	GSK3B	S7326	G7321R	7321	Missense	distal	-5	no	7.358	7.589	EPSD;PhosphoSitePlus	COSMIC	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	Q9UPN3	MACF1	P49841	GSK3B	S7326	G7321W	7321	Missense	distal	-5	no	7.358	7.332	EPSD;PhosphoSitePlus	COSMIC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	Q9UPN3	MACF1	P49841	GSK3B	S7326	R7327W	7327	Missense	proximal	1	no	7.358	7.575	EPSD;PhosphoSitePlus	COSMIC	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	Q9UPN3	MACF1	P49841	GSK3B	T7376	T7377I	7377	Missense	proximal	1	no	7.073	6.383	EPSD	COSMIC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	Q9UPN3	MACF1	P49841	GSK3B	T7376	R7382K	7382	Missense	distal	6	no	7.073	7.072	EPSD	COSMIC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	Q9UPN3	MACF1	P49841	GSK3B	S7380	T7377I	7377	Missense	distal	-3	no	7.336	7.424	EPSD	COSMIC	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	Q9UPN3	MACF1	P49841	GSK3B	S7380	R7382K	7382	Missense	proximal	2	no	7.336	7.270	EPSD	COSMIC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	Q00653	NFKB2	P49841	GSK3B	S277	V281L	281	Missense	distal	4	no	6.631	6.303	EPSD	COSMIC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	Q00653	NFKB2	P49841	GSK3B	T429	C432W	432	Missense	distal	3	no	8.729	8.832	EPSD	COSMIC	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	Q00653	NFKB2	P49841	GSK3B	S713	G719W	719	Missense	distal	6	no	7.328	7.316	EPSD	COSMIC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	Q00653	NFKB2	P49841	GSK3B	T732	T732M	732	Missense	central	0	yes	6.277	0.000	EPSD	COSMIC	6.007	Loss
CMGC_GSK_GSK3B_ST	Q00653	NFKB2	P49841	GSK3B	S790	Q788P	788	Missense	proximal	-2	no	5.961	6.262	EPSD	COSMIC	6.007	Gain
CMGC_GSK_GSK3B_ST	Q00653	NFKB2	P49841	GSK3B	S802	L798R	798	Missense	distal	-4	no	5.994	6.157	EPSD	COSMIC	6.007	Gain
CMGC_GSK_GSK3B_ST	Q00653	NFKB2	P49841	GSK3B	T806	P813L	813	Missense	distal	7	no	7.451	7.500	EPSD	COSMIC	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	Q00653	NFKB2	P49841	GSK3B	T810	P813L	813	Missense	distal	3	no	6.596	6.278	EPSD	COSMIC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	Q00653	NFKB2	P49841	GSK3B	S812	P813L	813	Missense	proximal	1	no	10.832	7.971	EPSD	COSMIC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	Q00653	NFKB2	P49841	GSK3B	S812	R819C	819	Missense	distal	7	no	10.832	10.786	EPSD	COSMIC;CCLE	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	Q00653	NFKB2	P49841	GSK3B	S814	P813L	813	Missense	proximal	-1	no	6.181	6.050	EPSD	COSMIC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	Q00653	NFKB2	P49841	GSK3B	S814	R819C	819	Missense	distal	5	no	6.181	4.625	EPSD	COSMIC;CCLE	6.007	Loss
CMGC_GSK_GSK3B_ST	Q00653	NFKB2	P49841	GSK3B	S816	P813L	813	Missense	distal	-3	no	6.677	6.804	EPSD	COSMIC	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	Q00653	NFKB2	P49841	GSK3B	S816	R819C	819	Missense	distal	3	no	6.677	6.833	EPSD	COSMIC;CCLE	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	Q00653	NFKB2	P49841	GSK3B	S866	S872T	872	Missense	distal	6	no	7.534	7.537	EPSD	COSMIC	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	P58012	FOXL2	P49841	GSK3B	S33	S33R	33	Missense	central	0	yes	7.625	0.000	PhosphoSitePlus	COSMIC	6.007	Loss
CMGC_GSK_GSK3B_ST	P58012	FOXL2	P49841	GSK3B	S33	G39R	39	Missense	distal	6	no	7.625	7.624	PhosphoSitePlus	COSMIC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	P58012	FOXL2	P49841	GSK3B	S211	S217F	217	Missense	distal	6	no	7.140	7.128	EPSD	COSMIC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	P58012	FOXL2	P49841	GSK3B	S211	C218W	218	Missense	distal	7	no	7.140	7.294	EPSD	COSMIC	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	P58012	FOXL2	P49841	GSK3B	S211	Q208R	208	Missense	distal	-3	no	7.140	7.279	EPSD	COSMIC	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	P58012	FOXL2	P49841	GSK3B	S238	G240S	240	Missense	proximal	2	no	7.385	7.643	EPSD	COSMIC	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	P58012	FOXL2	P49841	GSK3B	S238	G237C	237	Missense	proximal	-1	no	7.385	7.342	EPSD	COSMIC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	P58012	FOXL2	P49841	GSK3B	S238	S238G	238	Missense	central	0	yes	7.385	0.000	EPSD	COSMIC	6.007	Loss
CMGC_GSK_GSK3B_ST	P58012	FOXL2	P49841	GSK3B	S238	A243T	243	Missense	distal	5	no	7.385	7.437	EPSD	COSMIC	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	P58012	FOXL2	P49841	GSK3B	S238	V244L	244	Missense	distal	6	no	7.385	7.390	EPSD	COSMIC	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	P58012	FOXL2	P49841	GSK3B	S326	A331V	331	Missense	distal	5	no	7.202	6.775	EPSD	COSMIC;CCLE	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	O15294	OGT	P49841	GSK3B	S74	S78C	78	Missense	distal	4	no	6.379	0.247	EPSD	COSMIC	6.007	Loss
CMGC_GSK_GSK3B_ST	O15294	OGT	P49841	GSK3B	T325	R321C	321	Missense	distal	-4	no	6.046	5.119	EPSD	COSMIC	6.007	Loss
CMGC_GSK_GSK3B_ST	O15294	OGT	P49841	GSK3B	T325	N332K	332	Missense	distal	7	no	6.046	5.854	EPSD	COSMIC	6.007	Loss
CMGC_GSK_GSK3B_ST	O15294	OGT	P49841	GSK3B	T325	N332D	332	Missense	distal	7	no	6.046	5.978	EPSD	COSMIC	6.007	Loss
CMGC_GSK_GSK3B_ST	O15294	OGT	P49841	GSK3B	S365	N366D	366	Missense	proximal	1	no	4.372	6.788	EPSD	COSMIC	6.007	Gain
CMGC_GSK_GSK3B_ST	O15294	OGT	P49841	GSK3B	S369	N366D	366	Missense	distal	-3	no	6.082	6.223	EPSD	COSMIC	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	O15294	OGT	P49841	GSK3B	S369	G375R	375	Missense	distal	6	no	6.082	6.081	EPSD	COSMIC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	Q14449	GRB14	P49841	GSK3B	S358	Q355P	355	Missense	distal	-3	no	8.048	7.901	EPSD;PhosphoSitePlus	COSMIC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	Q14449	GRB14	P49841	GSK3B	S362	Q355P	355	Missense	distal	-7	no	8.428	8.411	PhosphoSitePlus;EPSD	COSMIC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	Q14449	GRB14	P49841	GSK3B	S366	I371V	371	Missense	distal	5	no	9.293	9.458	EPSD;PhosphoSitePlus	COSMIC	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	Q14449	GRB14	P49841	GSK3B	S366	S372P	372	Missense	distal	6	no	9.293	9.295	EPSD;PhosphoSitePlus	COSMIC	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	Q14449	GRB14	P49841	GSK3B	S419	R413C	413	Missense	distal	-6	no	10.782	10.828	EPSD;PhosphoSitePlus	COSMIC	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	Q14449	GRB14	P49841	GSK3B	S419	R413L	413	Missense	distal	-6	no	10.782	10.838	EPSD;PhosphoSitePlus	COSMIC	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	Q14449	GRB14	P49841	GSK3B	S419	G418C	418	Missense	proximal	-1	no	10.782	10.739	EPSD;PhosphoSitePlus	COSMIC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	Q14449	GRB14	P49841	GSK3B	S419	T421P	421	Missense	proximal	2	no	10.782	11.100	EPSD;PhosphoSitePlus	COSMIC	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	Q14449	GRB14	P49841	GSK3B	S423	G418C	418	Missense	distal	-5	no	7.814	7.867	EPSD;PhosphoSitePlus	COSMIC	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	Q14449	GRB14	P49841	GSK3B	S423	T421P	421	Missense	proximal	-2	no	7.814	8.043	EPSD;PhosphoSitePlus	COSMIC	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	P49768	PSEN1	P49841	GSK3B	S353	S346F	346	Missense	distal	-7	no	7.747	7.757	PhosphoSitePlus;EPSD	COSMIC	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	P49768	PSEN1	P49841	GSK3B	S353	R352H	352	Missense	proximal	-1	no	7.747	7.832	PhosphoSitePlus;EPSD	COSMIC;CCLE	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	P49768	PSEN1	P49841	GSK3B	T354	R352H	352	Missense	proximal	-2	no	6.842	6.852	EPSD	COSMIC;CCLE	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	P49768	PSEN1	P49841	GSK3B	S357	R352H	352	Missense	distal	-5	no	8.588	8.057	EPSD;PhosphoSitePlus	COSMIC;CCLE	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	P49768	PSEN1	P49841	GSK3B	S357	L364V	364	Missense	distal	7	no	8.588	9.027	EPSD;PhosphoSitePlus	COSMIC	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	O75122	CLASP2	P49841	GSK3B	S21	S25P	25	Missense	distal	4	no	6.655	3.684	EPSD	COSMIC	6.007	Loss
CMGC_GSK_GSK3B_ST	O75122	CLASP2	P49841	GSK3B	S310	A315E	315	Missense	distal	5	no	6.102	6.486	EPSD	COSMIC	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	O75122	CLASP2	P49841	GSK3B	S316	S323P	323	Missense	distal	7	no	7.599	7.536	EPSD	COSMIC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	O75122	CLASP2	P49841	GSK3B	S316	P318Q	318	Missense	proximal	2	no	7.599	7.378	EPSD	COSMIC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	O75122	CLASP2	P49841	GSK3B	S316	A315E	315	Missense	proximal	-1	no	7.599	7.742	EPSD	COSMIC	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	O75122	CLASP2	P49841	GSK3B	S320	S323P	323	Missense	distal	3	no	8.349	8.366	EPSD	COSMIC	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	O75122	CLASP2	P49841	GSK3B	S320	P318Q	318	Missense	proximal	-2	no	8.349	8.047	EPSD	COSMIC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	O75122	CLASP2	P49841	GSK3B	S320	A315E	315	Missense	distal	-5	no	8.349	8.502	EPSD	COSMIC	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	O75122	CLASP2	P49841	GSK3B	S336	R333H	333	Missense	distal	-3	no	6.468	6.411	EPSD	COSMIC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	O75122	CLASP2	P49841	GSK3B	S336	S337F	337	Missense	proximal	1	no	6.468	6.082	EPSD	COSMIC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	O75122	CLASP2	P49841	GSK3B	S336	W339L	339	Missense	distal	3	no	6.468	6.280	EPSD	COSMIC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	O75122	CLASP2	P49841	GSK3B	S360	S356I	356	Missense	distal	-4	no	9.257	6.774	EPSD	COSMIC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	O75122	CLASP2	P49841	GSK3B	S360	S355I	355	Missense	distal	-5	no	9.257	9.729	EPSD	COSMIC	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	O75122	CLASP2	P49841	GSK3B	S364	D371N	371	Missense	distal	7	no	8.449	8.517	EPSD	COSMIC	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	O75122	CLASP2	P49841	GSK3B	S368	I372L	372	Missense	distal	4	no	6.078	6.682	EPSD	COSMIC	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	O75122	CLASP2	P49841	GSK3B	S368	D371N	371	Missense	distal	3	no	6.078	6.031	EPSD	COSMIC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	O75122	CLASP2	P49841	GSK3B	S407	A406V	406	Missense	proximal	-1	no	6.398	6.601	EPSD	COSMIC	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	O75122	CLASP2	P49841	GSK3B	S407	D413N	413	Missense	distal	6	no	6.398	6.399	EPSD	COSMIC	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	O75122	CLASP2	P49841	GSK3B	S407	S412C	412	Missense	distal	5	no	6.398	5.158	EPSD	COSMIC	6.007	Loss
CMGC_GSK_GSK3B_ST	O75122	CLASP2	P49841	GSK3B	S447	R448Q	448	Missense	proximal	1	no	6.191	5.242	EPSD	COSMIC	6.007	Loss
CMGC_GSK_GSK3B_ST	O75122	CLASP2	P49841	GSK3B	S447	S453F	453	Missense	distal	6	no	6.191	6.178	EPSD	COSMIC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	O75122	CLASP2	P49841	GSK3B	S447	S447G	447	Missense	central	0	yes	6.191	0.000	EPSD	COSMIC	6.007	Loss
CMGC_GSK_GSK3B_ST	O75122	CLASP2	P49841	GSK3B	S447	V452A	452	Missense	distal	5	no	6.191	6.617	EPSD	COSMIC	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	O75122	CLASP2	P49841	GSK3B	S447	S453G	453	Missense	distal	6	no	6.191	6.188	EPSD	COSMIC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	O75122	CLASP2	P49841	GSK3B	S453	P457S	457	Missense	distal	4	no	4.392	7.364	EPSD	COSMIC	6.007	Gain
CMGC_GSK_GSK3B_ST	O75122	CLASP2	P49841	GSK3B	S455	R448Q	448	Missense	distal	-7	no	6.838	6.835	EPSD	COSMIC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	O75122	CLASP2	P49841	GSK3B	S455	P457S	457	Missense	proximal	2	no	6.838	6.394	EPSD	COSMIC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	O75122	CLASP2	P49841	GSK3B	S455	S453F	453	Missense	proximal	-2	no	6.838	6.508	EPSD	COSMIC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	O75122	CLASP2	P49841	GSK3B	S455	V452A	452	Missense	distal	-3	no	6.838	6.692	EPSD	COSMIC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	O75122	CLASP2	P49841	GSK3B	S455	R460L	460	Missense	distal	5	no	6.838	6.195	EPSD	COSMIC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	O75122	CLASP2	P49841	GSK3B	S455	S453G	453	Missense	proximal	-2	no	6.838	6.721	EPSD	COSMIC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	O75122	CLASP2	P49841	GSK3B	S455	S459F	459	Missense	distal	4	no	6.838	3.224	EPSD	COSMIC	6.007	Loss
CMGC_GSK_GSK3B_ST	O75122	CLASP2	P49841	GSK3B	S459	P457S	457	Missense	proximal	-2	no	10.297	10.040	EPSD	COSMIC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	O75122	CLASP2	P49841	GSK3B	S459	S453F	453	Missense	distal	-6	no	10.297	10.243	EPSD	COSMIC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	O75122	CLASP2	P49841	GSK3B	S459	V452A	452	Missense	distal	-7	no	10.297	10.298	EPSD	COSMIC	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	O75122	CLASP2	P49841	GSK3B	S459	R460L	460	Missense	proximal	1	no	10.297	9.756	EPSD	COSMIC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	O75122	CLASP2	P49841	GSK3B	S459	S453G	453	Missense	distal	-6	no	10.297	10.313	EPSD	COSMIC	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	O75122	CLASP2	P49841	GSK3B	S459	S459F	459	Missense	central	0	yes	10.297	0.000	EPSD	COSMIC	6.007	Loss
CMGC_GSK_GSK3B_ST	O75122	CLASP2	P49841	GSK3B	S463	P457S	457	Missense	distal	-6	no	8.885	8.864	EPSD	COSMIC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	O75122	CLASP2	P49841	GSK3B	S463	R460L	460	Missense	distal	-3	no	8.885	8.726	EPSD	COSMIC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	O75122	CLASP2	P49841	GSK3B	S463	S459F	459	Missense	distal	-4	no	8.885	7.731	EPSD	COSMIC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	O75122	CLASP2	P49841	GSK3B	S474	A472T	472	Missense	proximal	-2	no	5.857	6.219	EPSD	COSMIC	6.007	Gain
CMGC_GSK_GSK3B_ST	O75122	CLASP2	P49841	GSK3B	S474	Q481H	481	Missense	distal	7	no	5.857	6.393	EPSD	COSMIC	6.007	Gain
CMGC_GSK_GSK3B_ST	O75122	CLASP2	P49841	GSK3B	S499	S503C	503	Missense	distal	4	no	7.506	1.374	EPSD;PhosphoSitePlus	COSMIC	6.007	Loss
CMGC_GSK_GSK3B_ST	O75122	CLASP2	P49841	GSK3B	S499	S503N	503	Missense	distal	4	no	7.506	3.896	EPSD;PhosphoSitePlus	COSMIC	6.007	Loss
CMGC_GSK_GSK3B_ST	O75122	CLASP2	P49841	GSK3B	S499	R498Q	498	Missense	proximal	-1	no	7.506	7.537	EPSD;PhosphoSitePlus	COSMIC	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	O75122	CLASP2	P49841	GSK3B	S499	R493G	493	Missense	distal	-6	no	7.506	7.580	EPSD;PhosphoSitePlus	COSMIC	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	O75122	CLASP2	P49841	GSK3B	S499	I496N	496	Missense	distal	-3	no	7.506	7.298	EPSD;PhosphoSitePlus	COSMIC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	O75122	CLASP2	P49841	GSK3B	S503	S503C	503	Missense	central	0	yes	10.177	0.000	EPSD;PhosphoSitePlus	COSMIC	6.007	Loss
CMGC_GSK_GSK3B_ST	O75122	CLASP2	P49841	GSK3B	S503	S503N	503	Missense	central	0	yes	10.177	0.000	EPSD;PhosphoSitePlus	COSMIC	6.007	Loss
CMGC_GSK_GSK3B_ST	O75122	CLASP2	P49841	GSK3B	S503	R498Q	498	Missense	distal	-5	no	10.177	9.622	EPSD;PhosphoSitePlus	COSMIC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	O75122	CLASP2	P49841	GSK3B	S503	I496N	496	Missense	distal	-7	no	10.177	10.155	EPSD;PhosphoSitePlus	COSMIC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	O75122	CLASP2	P49841	GSK3B	S507	S503C	503	Missense	distal	-4	no	7.680	5.566	PhosphoSitePlus;EPSD	COSMIC	6.007	Loss
CMGC_GSK_GSK3B_ST	O75122	CLASP2	P49841	GSK3B	S507	S503N	503	Missense	distal	-4	no	7.680	6.382	PhosphoSitePlus;EPSD	COSMIC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	O75122	CLASP2	P49841	GSK3B	S512	R518C	518	Missense	distal	6	no	6.466	6.457	EPSD	COSMIC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	O75122	CLASP2	P49841	GSK3B	S512	R515I	515	Missense	distal	3	no	6.466	6.417	EPSD	COSMIC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	O75122	CLASP2	P49841	GSK3B	S512	R515S	515	Missense	distal	3	no	6.466	6.837	EPSD	COSMIC	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	O75122	CLASP2	P49841	GSK3B	S517	P520L	520	Missense	distal	3	no	6.946	6.628	EPSD	COSMIC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	O75122	CLASP2	P49841	GSK3B	S517	R518C	518	Missense	proximal	1	no	6.946	4.943	EPSD	COSMIC	6.007	Loss
CMGC_GSK_GSK3B_ST	O75122	CLASP2	P49841	GSK3B	S517	P520T	520	Missense	distal	3	no	6.946	6.895	EPSD	COSMIC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	O75122	CLASP2	P49841	GSK3B	S517	R515I	515	Missense	proximal	-2	no	6.946	7.051	EPSD	COSMIC	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	O75122	CLASP2	P49841	GSK3B	S517	R515S	515	Missense	proximal	-2	no	6.946	7.061	EPSD	COSMIC	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	O75122	CLASP2	P49841	GSK3B	S525	P520L	520	Missense	distal	-5	no	6.757	7.022	EPSD	COSMIC	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	O75122	CLASP2	P49841	GSK3B	S525	Q526H	526	Missense	proximal	1	no	6.757	6.325	EPSD	COSMIC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	O75122	CLASP2	P49841	GSK3B	S525	R518C	518	Missense	distal	-7	no	6.757	6.761	EPSD	COSMIC	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	O75122	CLASP2	P49841	GSK3B	S525	P520T	520	Missense	distal	-5	no	6.757	7.203	EPSD	COSMIC	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	O75122	CLASP2	P49841	GSK3B	S525	R530L	530	Missense	distal	5	no	6.757	6.114	EPSD	COSMIC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	O75122	CLASP2	P49841	GSK3B	S525	S525R	525	Missense	central	0	yes	6.757	0.000	EPSD	COSMIC	6.007	Loss
CMGC_GSK_GSK3B_ST	O75122	CLASP2	P49841	GSK3B	S525	S529I	529	Missense	distal	4	no	6.757	3.435	EPSD	COSMIC	6.007	Loss
CMGC_GSK_GSK3B_ST	O75122	CLASP2	P49841	GSK3B	S529	Q526H	526	Missense	distal	-3	no	9.192	9.274	EPSD	COSMIC	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	O75122	CLASP2	P49841	GSK3B	S529	R534W	534	Missense	distal	5	no	9.192	7.890	EPSD	COSMIC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	O75122	CLASP2	P49841	GSK3B	S529	R530L	530	Missense	proximal	1	no	9.192	8.651	EPSD	COSMIC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	O75122	CLASP2	P49841	GSK3B	S529	S525R	525	Missense	distal	-4	no	9.192	8.005	EPSD	COSMIC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	O75122	CLASP2	P49841	GSK3B	S529	R534L	534	Missense	distal	5	no	9.192	8.549	EPSD	COSMIC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	O75122	CLASP2	P49841	GSK3B	S529	S529I	529	Missense	central	0	yes	9.192	0.000	EPSD	COSMIC	6.007	Loss
CMGC_GSK_GSK3B_ST	O75122	CLASP2	P49841	GSK3B	S533	Q526H	526	Missense	distal	-7	no	9.513	9.516	EPSD;PhosphoSitePlus	COSMIC	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	O75122	CLASP2	P49841	GSK3B	S533	D539Y	539	Missense	distal	6	no	9.513	9.514	EPSD;PhosphoSitePlus	COSMIC	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	O75122	CLASP2	P49841	GSK3B	S533	R538I	538	Missense	distal	5	no	9.513	8.530	EPSD;PhosphoSitePlus	COSMIC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	O75122	CLASP2	P49841	GSK3B	S533	R534W	534	Missense	proximal	1	no	9.513	9.731	EPSD;PhosphoSitePlus	COSMIC	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	O75122	CLASP2	P49841	GSK3B	S533	R530L	530	Missense	distal	-3	no	9.513	9.353	EPSD;PhosphoSitePlus	COSMIC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	O75122	CLASP2	P49841	GSK3B	S533	R534L	534	Missense	proximal	1	no	9.513	8.972	EPSD;PhosphoSitePlus	COSMIC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	O75122	CLASP2	P49841	GSK3B	S533	S529I	529	Missense	distal	-4	no	9.513	7.030	EPSD;PhosphoSitePlus	COSMIC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	O75122	CLASP2	P49841	GSK3B	S537	D539Y	539	Missense	proximal	2	no	10.617	10.293	EPSD;PhosphoSitePlus	COSMIC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	O75122	CLASP2	P49841	GSK3B	S537	R538I	538	Missense	proximal	1	no	10.617	9.056	EPSD;PhosphoSitePlus	COSMIC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	O75122	CLASP2	P49841	GSK3B	S537	R534W	534	Missense	distal	-3	no	10.617	10.547	EPSD;PhosphoSitePlus	COSMIC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	O75122	CLASP2	P49841	GSK3B	S537	R530L	530	Missense	distal	-7	no	10.617	10.599	EPSD;PhosphoSitePlus	COSMIC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	O75122	CLASP2	P49841	GSK3B	S537	R534L	534	Missense	distal	-3	no	10.617	10.458	EPSD;PhosphoSitePlus	COSMIC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	O75122	CLASP2	P49841	GSK3B	S541	D539Y	539	Missense	proximal	-2	no	8.160	7.856	EPSD	COSMIC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	O75122	CLASP2	P49841	GSK3B	S541	R538I	538	Missense	distal	-3	no	8.160	8.105	EPSD	COSMIC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	O75122	CLASP2	P49841	GSK3B	S541	R534W	534	Missense	distal	-7	no	8.160	8.170	EPSD	COSMIC	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	O75122	CLASP2	P49841	GSK3B	S541	P548S	548	Missense	distal	7	no	8.160	8.223	EPSD	COSMIC	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	O75122	CLASP2	P49841	GSK3B	S541	R534L	534	Missense	distal	-7	no	8.160	8.142	EPSD	COSMIC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	O75122	CLASP2	P49841	GSK3B	S551	S557P	557	Missense	distal	6	no	7.726	7.728	EPSD	COSMIC	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	O75122	CLASP2	P49841	GSK3B	S551	L549F	549	Missense	proximal	-2	no	7.726	7.470	EPSD	COSMIC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	O75122	CLASP2	P49841	GSK3B	S551	P548S	548	Missense	distal	-3	no	7.726	7.843	EPSD	COSMIC	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	O75122	CLASP2	P49841	GSK3B	S551	R552G	552	Missense	proximal	1	no	7.726	6.852	EPSD	COSMIC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	O75122	CLASP2	P49841	GSK3B	S580	Q578L	578	Missense	proximal	-2	no	6.345	6.316	EPSD	COSMIC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	O75122	CLASP2	P49841	GSK3B	S580	R581Q	581	Missense	proximal	1	no	6.345	5.396	EPSD	COSMIC	6.007	Loss
CMGC_GSK_GSK3B_ST	O75122	CLASP2	P49841	GSK3B	S583	Q578L	578	Missense	distal	-5	no	6.318	6.284	EPSD	COSMIC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	O75122	CLASP2	P49841	GSK3B	S583	R581Q	581	Missense	proximal	-2	no	6.318	6.389	EPSD	COSMIC	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	O75122	CLASP2	P49841	GSK3B	S585	R581Q	581	Missense	distal	-4	no	5.902	6.259	EPSD	COSMIC	6.007	Gain
CMGC_GSK_GSK3B_ST	O75122	CLASP2	P49841	GSK3B	S585	L592M	592	Missense	distal	7	no	5.902	6.285	EPSD	COSMIC	6.007	Gain
CMGC_GSK_GSK3B_ST	O75122	CLASP2	P49841	GSK3B	S630	A625G	625	Missense	distal	-5	no	5.847	6.036	EPSD	COSMIC	6.007	Gain
CMGC_GSK_GSK3B_ST	O75122	CLASP2	P49841	GSK3B	S892	S888F	888	Missense	distal	-4	no	6.577	5.423	EPSD	COSMIC	6.007	Loss
CMGC_GSK_GSK3B_ST	O75122	CLASP2	P49841	GSK3B	T919	P922S	922	Missense	distal	3	no	6.236	6.218	EPSD	COSMIC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	O75122	CLASP2	P49841	GSK3B	S921	P922S	922	Missense	proximal	1	no	6.073	2.228	EPSD	COSMIC	6.007	Loss
CMGC_GSK_GSK3B_ST	O75122	CLASP2	P49841	GSK3B	S1053	D1050Y	1050	Missense	distal	-3	no	7.776	7.871	EPSD	COSMIC	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	O75122	CLASP2	P49841	GSK3B	S1053	S1053G	1053	Missense	central	0	yes	7.776	0.000	EPSD	COSMIC	6.007	Loss
CMGC_GSK_GSK3B_ST	O75122	CLASP2	P49841	GSK3B	S1057	D1050Y	1050	Missense	distal	-7	no	6.469	6.495	EPSD	COSMIC	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	O75122	CLASP2	P49841	GSK3B	S1057	S1053G	1053	Missense	distal	-4	no	6.469	6.041	EPSD	COSMIC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	Q6PGQ7	BORA	P49841	GSK3B	S112	P113A	113	Missense	proximal	1	no	7.110	3.378	EPSD	COSMIC	6.007	Loss
CMGC_GSK_GSK3B_ST	Q6PGQ7	BORA	P49841	GSK3B	S268	S270L	270	Missense	proximal	2	no	6.184	6.244	EPSD	COSMIC	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	Q6PGQ7	BORA	P49841	GSK3B	S268	S270T	270	Missense	proximal	2	no	6.184	6.311	EPSD	COSMIC	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	Q6PGQ7	BORA	P49841	GSK3B	S270	S270L	270	Missense	central	0	yes	9.887	0.000	EPSD	COSMIC	6.007	Loss
CMGC_GSK_GSK3B_ST	Q6PGQ7	BORA	P49841	GSK3B	S270	T276A	276	Missense	distal	6	no	9.887	9.883	EPSD	COSMIC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	Q6PGQ7	BORA	P49841	GSK3B	S274	S270L	270	Missense	distal	-4	no	9.910	8.560	EPSD;PhosphoSitePlus	COSMIC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	Q6PGQ7	BORA	P49841	GSK3B	S274	S270T	270	Missense	distal	-4	no	9.910	9.574	EPSD;PhosphoSitePlus	COSMIC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	Q6PGQ7	BORA	P49841	GSK3B	S274	T276A	276	Missense	proximal	2	no	9.910	9.791	EPSD;PhosphoSitePlus	COSMIC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	Q6PGQ7	BORA	P49841	GSK3B	S278	T276A	276	Missense	proximal	-2	no	7.479	7.117	PhosphoSitePlus;EPSD	COSMIC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	Q6PGQ7	BORA	P49841	GSK3B	T342	Q343R	343	Missense	proximal	1	no	5.521	6.469	EPSD	COSMIC	6.007	Gain
CMGC_GSK_GSK3B_ST	Q6PGQ7	BORA	P49841	GSK3B	T446	T446K	446	Missense	central	0	yes	7.024	0.000	EPSD	COSMIC	6.007	Loss
CMGC_GSK_GSK3B_ST	O95863	SNAI1	P49841	GSK3B	S82	R84T	84	Missense	proximal	2	no	6.302	6.410	EPSD	COSMIC	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	O95863	SNAI1	P49841	GSK3B	S82	V85M	85	Missense	distal	3	no	6.302	6.319	EPSD	COSMIC	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	O95863	SNAI1	P49841	GSK3B	S96	P102S	102	Missense	distal	6	no	8.318	8.316	EPSD;PhosphoSitePlus	COSMIC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	O95863	SNAI1	P49841	GSK3B	S100	P102S	102	Missense	proximal	2	no	9.519	9.075	EPSD;PhosphoSitePlus	COSMIC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	O95863	SNAI1	P49841	GSK3B	S100	P105Q	105	Missense	distal	5	no	9.519	8.542	EPSD;PhosphoSitePlus	COSMIC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	O95863	SNAI1	P49841	GSK3B	S104	P102S	102	Missense	proximal	-2	no	9.476	9.220	PhosphoSitePlus;EPSD	COSMIC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	O95863	SNAI1	P49841	GSK3B	S104	P105Q	105	Missense	proximal	1	no	9.476	6.208	PhosphoSitePlus;EPSD	COSMIC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	O95863	SNAI1	P49841	GSK3B	S107	P102S	102	Missense	distal	-5	no	11.906	12.063	EPSD;PhosphoSitePlus	COSMIC	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	O95863	SNAI1	P49841	GSK3B	S107	P105Q	105	Missense	proximal	-2	no	11.906	11.605	EPSD;PhosphoSitePlus	COSMIC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	O95863	SNAI1	P49841	GSK3B	S111	P105Q	105	Missense	distal	-6	no	6.721	6.695	EPSD;PhosphoSitePlus	COSMIC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	P19793	RXRA	P49841	GSK3B	S49	P50S	50	Missense	proximal	1	no	9.069	5.224	PhosphoSitePlus;EPSD	COSMIC;GDSC;CCLE	6.007	Loss
CMGC_GSK_GSK3B_ST	P19793	RXRA	P49841	GSK3B	S66	G60V	60	Missense	distal	-6	no	7.961	7.877	EPSD;PhosphoSitePlus	COSMIC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	P19793	RXRA	P49841	GSK3B	T82	G86C	86	Missense	distal	4	no	6.834	3.945	EPSD	COSMIC	6.007	Loss
CMGC_GSK_GSK3B_ST	P19793	RXRA	P49841	GSK3B	S260	M254I	254	Missense	distal	-6	no	6.299	6.289	EPSD	COSMIC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	P05412	JUN	P49841	GSK3B	S58	L53F	53	Missense	distal	-5	no	6.002	6.453	EPSD	COSMIC	6.007	Gain
CMGC_GSK_GSK3B_ST	P05412	JUN	P49841	GSK3B	S58	P51T	51	Missense	distal	-7	no	6.002	6.031	EPSD	COSMIC;CCLE	6.007	Gain
CMGC_GSK_GSK3B_ST	P05412	JUN	P49841	GSK3B	S58	L61F	61	Missense	distal	3	no	6.002	6.092	EPSD	COSMIC	6.007	Gain
CMGC_GSK_GSK3B_ST	P05412	JUN	P49841	GSK3B	S63	K56N	56	Missense	distal	-7	no	6.218	6.203	EPSD	COSMIC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	P05412	JUN	P49841	GSK3B	S63	L61F	61	Missense	proximal	-2	no	6.218	5.962	EPSD	COSMIC	6.007	Loss
CMGC_GSK_GSK3B_ST	P05412	JUN	P49841	GSK3B	S73	R78H	78	Missense	distal	5	no	7.671	6.682	EPSD	COSMIC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	P05412	JUN	P49841	GSK3B	T91	P92Q	92	Missense	proximal	1	no	8.831	5.563	EPSD	COSMIC	6.007	Loss
CMGC_GSK_GSK3B_ST	P05412	JUN	P49841	GSK3B	T91	L98M	98	Missense	distal	7	no	8.831	9.214	EPSD	COSMIC	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	P05412	JUN	P49841	GSK3B	T91	P94S	94	Missense	distal	3	no	8.831	8.813	EPSD	COSMIC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	P05412	JUN	P49841	GSK3B	T93	P100L	100	Missense	distal	7	no	6.874	6.923	EPSD	COSMIC	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	P05412	JUN	P49841	GSK3B	T93	P92Q	92	Missense	proximal	-1	no	6.874	6.712	EPSD	COSMIC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	P05412	JUN	P49841	GSK3B	T93	L98M	98	Missense	distal	5	no	6.874	7.062	EPSD	COSMIC	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	P05412	JUN	P49841	GSK3B	T93	P94S	94	Missense	proximal	1	no	6.874	3.029	EPSD	COSMIC	6.007	Loss
CMGC_GSK_GSK3B_ST	P05412	JUN	P49841	GSK3B	T239	P240Q	240	Missense	proximal	1	no	10.446	7.178	EPSD;PhosphoSitePlus	COSMIC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	P05412	JUN	P49841	GSK3B	T239	T239I	239	Missense	central	0	yes	10.446	0.000	EPSD;PhosphoSitePlus	COSMIC	6.007	Loss
CMGC_GSK_GSK3B_ST	P05412	JUN	P49841	GSK3B	S243	P240Q	240	Missense	distal	-3	no	8.558	8.705	PhosphoSitePlus;EPSD	COSMIC	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	P05412	JUN	P49841	GSK3B	S243	T239I	239	Missense	distal	-4	no	8.558	6.411	PhosphoSitePlus;EPSD	COSMIC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	Q9UMX1	SUFU	P49841	GSK3B	S342	R343H	343	Missense	proximal	1	no	7.675	6.295	PhosphoSitePlus	COSMIC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	Q9UMX1	SUFU	P49841	GSK3B	S342	P341L	341	Missense	proximal	-1	no	7.675	7.544	PhosphoSitePlus	COSMIC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	Q9UMX1	SUFU	P49841	GSK3B	S342	E348K	348	Missense	distal	6	no	7.675	7.676	PhosphoSitePlus	COSMIC	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	Q9UMX1	SUFU	P49841	GSK3B	S349	R343H	343	Missense	distal	-6	no	6.655	6.678	EPSD	COSMIC	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	Q9UMX1	SUFU	P49841	GSK3B	S349	S352F	352	Missense	distal	3	no	6.655	6.444	EPSD	COSMIC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	Q9UMX1	SUFU	P49841	GSK3B	S349	A354T	354	Missense	distal	5	no	6.655	6.707	EPSD	COSMIC	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	Q9UMX1	SUFU	P49841	GSK3B	S349	E348K	348	Missense	proximal	-1	no	6.655	6.722	EPSD	COSMIC	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	O00213	APBB1	P49841	GSK3B	S287	P283L	283	Missense	distal	-4	no	6.458	5.672	EPSD	COSMIC	6.007	Loss
CMGC_GSK_GSK3B_ST	O00213	APBB1	P49841	GSK3B	S287	P288T	288	Missense	proximal	1	no	6.458	3.267	EPSD	COSMIC	6.007	Loss
CMGC_GSK_GSK3B_ST	O00213	APBB1	P49841	GSK3B	S287	R285P	285	Missense	proximal	-2	no	6.458	6.830	EPSD	COSMIC	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	O00213	APBB1	P49841	GSK3B	S289	E296V	296	Missense	distal	7	no	7.898	8.284	EPSD	COSMIC	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	O00213	APBB1	P49841	GSK3B	S289	P283L	283	Missense	distal	-6	no	7.898	7.876	EPSD	COSMIC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	O00213	APBB1	P49841	GSK3B	S289	P288T	288	Missense	proximal	-1	no	7.898	7.766	EPSD	COSMIC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	O00213	APBB1	P49841	GSK3B	S289	S293I	293	Missense	distal	4	no	7.898	4.576	EPSD	COSMIC	6.007	Loss
CMGC_GSK_GSK3B_ST	O00213	APBB1	P49841	GSK3B	S289	R285P	285	Missense	distal	-4	no	7.898	8.521	EPSD	COSMIC	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	O00213	APBB1	P49841	GSK3B	T579	H582R	582	Missense	distal	3	no	7.653	7.311	PhosphoSitePlus	COSMIC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	O00213	APBB1	P49841	GSK3B	T579	R575H	575	Missense	distal	-4	no	7.653	7.752	PhosphoSitePlus	COSMIC	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	O00213	APBB1	P49841	GSK3B	T579	A586V	586	Missense	distal	7	no	7.653	7.731	PhosphoSitePlus	COSMIC	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	O00213	APBB1	P49841	GSK3B	S699	K703T	703	Missense	distal	4	no	5.286	7.620	EPSD	COSMIC	6.007	Gain
CMGC_GSK_GSK3B_ST	P03372	ESR1	P49841	GSK3B	S102	F97L	97	Missense	distal	-5	no	9.469	9.019	PhosphoSitePlus;EPSD	COSMIC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	P03372	ESR1	P49841	GSK3B	S102	M109T	109	Missense	distal	7	no	9.469	9.042	PhosphoSitePlus;EPSD	COSMIC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	P03372	ESR1	P49841	GSK3B	S106	P113L	113	Missense	distal	7	no	9.203	9.252	EPSD;PhosphoSitePlus	COSMIC	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	P03372	ESR1	P49841	GSK3B	S106	P113Q	113	Missense	distal	7	no	9.203	9.356	EPSD;PhosphoSitePlus	COSMIC	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	P03372	ESR1	P49841	GSK3B	S106	H112L	112	Missense	distal	6	no	9.203	9.208	EPSD;PhosphoSitePlus	COSMIC	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	P03372	ESR1	P49841	GSK3B	S106	M109T	109	Missense	distal	3	no	9.203	9.361	EPSD;PhosphoSitePlus	COSMIC	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	P03372	ESR1	P49841	GSK3B	S118	P113L	113	Missense	distal	-5	no	5.766	6.032	EPSD;PhosphoSitePlus	COSMIC	6.007	Gain
CMGC_GSK_GSK3B_ST	P03372	ESR1	P49841	GSK3B	S118	P113Q	113	Missense	distal	-5	no	5.766	6.066	EPSD;PhosphoSitePlus	COSMIC	6.007	Gain
CMGC_GSK_GSK3B_ST	P03372	ESR1	P49841	GSK3B	S294	K299R	299	Missense	distal	5	no	5.747	6.622	EPSD	COSMIC	6.007	Gain
CMGC_GSK_GSK3B_ST	P03372	ESR1	P49841	GSK3B	S294	L296P	296	Missense	proximal	2	no	5.747	6.131	EPSD	COSMIC	6.007	Gain
CMGC_GSK_GSK3B_ST	P03372	ESR1	P49841	GSK3B	S294	N290K	290	Missense	distal	-4	no	5.747	6.180	EPSD	COSMIC	6.007	Gain
CMGC_GSK_GSK3B_ST	P03372	ESR1	P49841	GSK3B	S305	K303R	303	Missense	proximal	-2	no	6.457	6.476	EPSD	COSMIC	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	P03372	ESR1	P49841	GSK3B	S305	K299R	299	Missense	distal	-6	no	6.457	6.463	EPSD	COSMIC	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	P03372	ESR1	P49841	GSK3B	S305	N304S	304	Missense	proximal	-1	no	6.457	6.396	EPSD	COSMIC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	P03372	ESR1	P49841	GSK3B	S305	R300C	300	Missense	distal	-5	no	6.457	6.279	EPSD	COSMIC;CCLE	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	P03372	ESR1	P49841	GSK3B	S305	A307P	307	Missense	proximal	2	no	6.457	6.894	EPSD	COSMIC	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	P03372	ESR1	P49841	GSK3B	S305	N304H	304	Missense	proximal	-1	no	6.457	6.344	EPSD	COSMIC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	P03372	ESR1	P49841	GSK3B	T570	D564Y	564	Missense	distal	-6	no	6.049	5.988	EPSD	COSMIC	6.007	Loss
CMGC_GSK_GSK3B_ST	P03372	ESR1	P49841	GSK3B	T570	D564N	564	Missense	distal	-6	no	6.049	6.072	EPSD	COSMIC	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	O95271	TNKS	P49841	GSK3B	T839	T839I	839	Missense	central	0	yes	6.423	0.000	EPSD	COSMIC	6.007	Loss
CMGC_GSK_GSK3B_ST	O95271	TNKS	P49841	GSK3B	T839	P840H	840	Missense	proximal	1	no	6.423	2.723	EPSD	COSMIC	6.007	Loss
CMGC_GSK_GSK3B_ST	O95271	TNKS	P49841	GSK3B	S978	S984N	984	Missense	distal	6	no	9.811	9.805	EPSD;PhosphoSitePlus	COSMIC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	O95271	TNKS	P49841	GSK3B	T982	S987L	987	Missense	distal	5	no	8.175	7.849	PhosphoSitePlus;EPSD	COSMIC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	O95271	TNKS	P49841	GSK3B	T982	A988T	988	Missense	distal	6	no	8.175	8.179	PhosphoSitePlus;EPSD	COSMIC	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	O95271	TNKS	P49841	GSK3B	T982	S984N	984	Missense	proximal	2	no	8.175	7.643	PhosphoSitePlus;EPSD	COSMIC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	O95271	TNKS	P49841	GSK3B	S987	A988T	988	Missense	proximal	1	no	5.869	6.410	EPSD;PhosphoSitePlus	COSMIC	6.007	Gain
CMGC_GSK_GSK3B_ST	Q9NS23	RASSF1	P49841	GSK3B	T43	R36Q	36	Missense	distal	-7	no	6.775	6.772	EPSD	COSMIC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	Q9NS23	RASSF1	P49841	GSK3B	T43	P42S	42	Missense	proximal	-1	no	6.775	6.719	EPSD	COSMIC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	Q9NS23	RASSF1	P49841	GSK3B	T43	G37S	37	Missense	distal	-6	no	6.775	6.759	EPSD	COSMIC;CCLE	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	Q9NS23	RASSF1	P49841	GSK3B	T43	R50H	50	Missense	distal	7	no	6.775	6.963	EPSD	COSMIC	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	Q9NS23	RASSF1	P49841	GSK3B	T43	R50C	50	Missense	distal	7	no	6.775	6.730	EPSD	COSMIC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	Q9NS23	RASSF1	P49841	GSK3B	T43	V47A	47	Missense	distal	4	no	6.775	6.753	EPSD	COSMIC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	Q9NS23	RASSF1	P49841	GSK3B	S135	I139T	139	Missense	distal	4	no	4.534	6.987	EPSD	COSMIC;GDSC;CCLE	6.007	Gain
CMGC_GSK_GSK3B_ST	Q9NS23	RASSF1	P49841	GSK3B	S179	P181S	181	Missense	proximal	2	no	8.019	7.575	PhosphoSitePlus;EPSD	COSMIC;GDSC;CCLE	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	Q9NS23	RASSF1	P49841	GSK3B	S179	P177S	177	Missense	proximal	-2	no	8.019	7.763	PhosphoSitePlus;EPSD	COSMIC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	Q9NS23	RASSF1	P49841	GSK3B	S179	S179R	179	Missense	central	0	yes	8.019	0.000	PhosphoSitePlus;EPSD	COSMIC	6.007	Loss
CMGC_GSK_GSK3B_ST	Q9NS23	RASSF1	P49841	GSK3B	S179	R176C	176	Missense	distal	-3	no	8.019	7.954	PhosphoSitePlus;EPSD	COSMIC;GDSC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	Q9NS23	RASSF1	P49841	GSK3B	S179	S183R	183	Missense	distal	4	no	8.019	4.981	PhosphoSitePlus;EPSD	COSMIC	6.007	Loss
CMGC_GSK_GSK3B_ST	Q9NS23	RASSF1	P49841	GSK3B	S179	R176H	176	Missense	distal	-3	no	8.019	7.962	PhosphoSitePlus;EPSD	COSMIC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	Q9NS23	RASSF1	P49841	GSK3B	S188	A192V	192	Missense	distal	4	no	6.000	6.022	EPSD	COSMIC	6.007	Gain
CMGC_GSK_GSK3B_ST	Q9NS23	RASSF1	P49841	GSK3B	S188	S183R	183	Missense	distal	-5	no	6.000	6.698	EPSD	COSMIC	6.007	Gain
CMGC_GSK_GSK3B_ST	O75925	PIAS1	P49841	GSK3B	S90	S83N	83	Missense	distal	-7	no	7.982	7.988	EPSD	COSMIC	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	O75925	PIAS1	P49841	GSK3B	S90	P86T	86	Missense	distal	-4	no	7.982	8.210	EPSD	COSMIC	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	O75925	PIAS1	P49841	GSK3B	S106	S106L	106	Missense	central	0	yes	6.364	0.000	EPSD	COSMIC	6.007	Loss
CMGC_GSK_GSK3B_ST	O75925	PIAS1	P49841	GSK3B	S106	D100Y	100	Missense	distal	-6	no	6.364	6.303	EPSD	COSMIC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	O75925	PIAS1	P49841	GSK3B	S106	L108S	108	Missense	proximal	2	no	6.364	6.305	EPSD	COSMIC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	O75925	PIAS1	P49841	GSK3B	S106	H102Y	102	Missense	distal	-4	no	6.364	6.652	EPSD	COSMIC	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	O75925	PIAS1	P49841	GSK3B	S106	P110L	110	Missense	distal	4	no	6.364	6.618	EPSD	COSMIC;GDSC;CCLE	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	O75925	PIAS1	P49841	GSK3B	S332	L334P	334	Missense	proximal	2	no	5.661	6.045	EPSD	COSMIC	6.007	Gain
CMGC_GSK_GSK3B_ST	P15941	MUC1	P49841	GSK3B	T744	P748T	748	Missense	distal	4	no	4.956	7.058	EPSD	COSMIC	6.007	Gain
CMGC_GSK_GSK3B_ST	P15941	MUC1	P49841	GSK3B	S1227	P1228R	1228	Missense	proximal	1	no	7.034	4.714	PhosphoSitePlus	COSMIC	6.007	Loss
CMGC_GSK_GSK3B_ST	Q9NZQ7	CD274	P49841	GSK3B	S279	T285A	285	Missense	distal	6	no	7.625	7.621	EPSD	COSMIC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	Q9NZQ7	CD274	P49841	GSK3B	S279	T277K	277	Missense	proximal	-2	no	7.625	7.463	EPSD	COSMIC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	Q9NZQ7	CD274	P49841	GSK3B	S279	C272Y	272	Missense	distal	-7	no	7.625	7.631	EPSD	COSMIC	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	Q8NHW3	MAFA	P49841	GSK3B	T134	N127K	127	Missense	distal	-7	no	7.528	7.544	EPSD	COSMIC	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	P0DMV8	HSPA1A	P49841	GSK3B	S633	G626C	626	Missense	distal	-7	no	6.469	6.494	EPSD	COSMIC	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	P0DMV8	HSPA1A	P49841	GSK3B	S633	G629A	629	Missense	distal	-4	no	6.469	5.738	EPSD	COSMIC	6.007	Loss
CMGC_GSK_GSK3B_ST	Q14596	NBR1	P49841	GSK3B	S273	F270L	270	Missense	distal	-3	no	6.780	6.722	EPSD	COSMIC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	Q14596	NBR1	P49841	GSK3B	S273	K274E	274	Missense	proximal	1	no	6.780	6.492	EPSD	COSMIC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	Q14596	NBR1	P49841	GSK3B	S833	H829R	829	Missense	distal	-4	no	9.121	9.022	EPSD	COSMIC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	Q14596	NBR1	P49841	GSK3B	S833	P834S	834	Missense	proximal	1	no	9.121	5.276	EPSD	COSMIC;GDSC;CCLE	6.007	Loss
CMGC_GSK_GSK3B_ST	Q14596	NBR1	P49841	GSK3B	S833	S833F	833	Missense	central	0	yes	9.121	0.000	EPSD	COSMIC	6.007	Loss
CMGC_GSK_GSK3B_ST	Q14596	NBR1	P49841	GSK3B	T841	S846F	846	Missense	distal	5	no	6.065	5.398	EPSD	COSMIC	6.007	Loss
CMGC_GSK_GSK3B_ST	Q14596	NBR1	P49841	GSK3B	T841	P834S	834	Missense	distal	-7	no	6.065	6.067	EPSD	COSMIC;GDSC;CCLE	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	Q14596	NBR1	P49841	GSK3B	S891	S895C	895	Missense	distal	4	no	6.696	0.564	EPSD	COSMIC	6.007	Loss
CMGC_GSK_GSK3B_ST	P12036	NEFH	P49841	GSK3B	T53	S57F	57	Missense	distal	4	no	6.175	2.561	EPSD	COSMIC	6.007	Loss
CMGC_GSK_GSK3B_ST	P12036	NEFH	P49841	GSK3B	S57	S57F	57	Missense	central	0	yes	7.937	0.000	EPSD	COSMIC	6.007	Loss
CMGC_GSK_GSK3B_ST	P12036	NEFH	P49841	GSK3B	S59	R66C	66	Missense	distal	7	no	6.913	6.867	EPSD	COSMIC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	P12036	NEFH	P49841	GSK3B	S59	S57F	57	Missense	proximal	-2	no	6.913	6.582	EPSD	COSMIC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	P12036	NEFH	P49841	GSK3B	S61	R66C	66	Missense	distal	5	no	6.829	5.272	EPSD	COSMIC	6.007	Loss
CMGC_GSK_GSK3B_ST	P12036	NEFH	P49841	GSK3B	S61	S57F	57	Missense	distal	-4	no	6.829	5.675	EPSD	COSMIC	6.007	Loss
CMGC_GSK_GSK3B_ST	P12036	NEFH	P49841	GSK3B	S61	A68T	68	Missense	distal	7	no	6.829	6.422	EPSD	COSMIC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	P12036	NEFH	P49841	GSK3B	S72	A68T	68	Missense	distal	-4	no	5.723	6.547	EPSD	COSMIC	6.007	Gain
CMGC_GSK_GSK3B_ST	P12036	NEFH	P49841	GSK3B	S511	E515K	515	Missense	distal	4	no	6.010	4.828	EPSD	COSMIC	6.007	Loss
CMGC_GSK_GSK3B_ST	P12036	NEFH	P49841	GSK3B	S518	E515K	515	Missense	distal	-3	no	7.766	7.776	EPSD	COSMIC	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	P12036	NEFH	P49841	GSK3B	S532	A528P	528	Missense	distal	-4	no	7.606	8.202	EPSD	COSMIC	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	P12036	NEFH	P49841	GSK3B	S532	P533A	533	Missense	proximal	1	no	7.606	3.873	EPSD	COSMIC	6.007	Loss
CMGC_GSK_GSK3B_ST	P12036	NEFH	P49841	GSK3B	S546	A542S	542	Missense	distal	-4	no	5.540	6.699	EPSD	COSMIC	6.007	Gain
CMGC_GSK_GSK3B_ST	P12036	NEFH	P49841	GSK3B	S552	K555M	555	Missense	distal	3	no	7.707	7.643	EPSD	COSMIC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	P12036	NEFH	P49841	GSK3B	S594	P595T	595	Missense	proximal	1	no	6.174	2.983	EPSD	COSMIC	6.007	Loss
CMGC_GSK_GSK3B_ST	P12036	NEFH	P49841	GSK3B	S600	P595T	595	Missense	distal	-5	no	5.884	6.330	EPSD	COSMIC	6.007	Gain
CMGC_GSK_GSK3B_ST	P12036	NEFH	P49841	GSK3B	S606	P607S	607	Missense	proximal	1	no	7.430	3.585	EPSD	COSMIC	6.007	Loss
CMGC_GSK_GSK3B_ST	P12036	NEFH	P49841	GSK3B	S620	E624K	624	Missense	distal	4	no	6.904	5.722	EPSD	COSMIC	6.007	Loss
CMGC_GSK_GSK3B_ST	P12036	NEFH	P49841	GSK3B	S634	A638T	638	Missense	distal	4	no	4.965	6.508	EPSD	COSMIC	6.007	Gain
CMGC_GSK_GSK3B_ST	P12036	NEFH	P49841	GSK3B	S640	K637E	637	Missense	distal	-3	no	7.717	7.707	EPSD	COSMIC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	P12036	NEFH	P49841	GSK3B	S640	A638T	638	Missense	proximal	-2	no	7.717	8.079	EPSD	COSMIC	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	P12036	NEFH	P49841	GSK3B	S688	S682F	682	Missense	distal	-6	no	6.665	6.612	EPSD	COSMIC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	P12036	NEFH	P49841	GSK3B	S702	E706G	706	Missense	distal	4	no	7.076	5.853	EPSD	COSMIC;GDSC;CCLE	6.007	Loss
CMGC_GSK_GSK3B_ST	P12036	NEFH	P49841	GSK3B	S702	E706Q	706	Missense	distal	4	no	7.076	5.533	EPSD	COSMIC	6.007	Loss
CMGC_GSK_GSK3B_ST	P12036	NEFH	P49841	GSK3B	S710	E706G	706	Missense	distal	-4	no	6.340	6.509	EPSD	COSMIC;GDSC;CCLE	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	P12036	NEFH	P49841	GSK3B	S710	E706Q	706	Missense	distal	-4	no	6.340	6.108	EPSD	COSMIC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	P12036	NEFH	P49841	GSK3B	S744	E748D	748	Missense	distal	4	no	7.026	6.623	EPSD	COSMIC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	P12036	NEFH	P49841	GSK3B	S758	A756V	756	Missense	proximal	-2	no	6.133	6.435	EPSD	COSMIC	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	P12036	NEFH	P49841	GSK3B	S758	E754K	754	Missense	distal	-4	no	6.133	5.865	EPSD	COSMIC	6.007	Loss
CMGC_GSK_GSK3B_ST	P12036	NEFH	P49841	GSK3B	S807	P802A	802	Missense	distal	-5	no	7.675	8.109	EPSD	COSMIC	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	P12036	NEFH	P49841	GSK3B	S807	P802S	802	Missense	distal	-5	no	7.675	7.832	EPSD	COSMIC	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	P12036	NEFH	P49841	GSK3B	S828	E832K	832	Missense	distal	4	no	7.334	6.152	EPSD	COSMIC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	O00429	DNM1L	P49841	GSK3B	S40	G37R	37	Missense	distal	-3	no	8.819	8.992	PhosphoSitePlus;EPSD	COSMIC	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	O00429	DNM1L	P49841	GSK3B	S44	G37R	37	Missense	distal	-7	no	6.165	6.185	EPSD;PhosphoSitePlus	COSMIC	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	O00429	DNM1L	P49841	GSK3B	S544	A543S	543	Missense	proximal	-1	no	6.419	6.574	EPSD	COSMIC	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	O00429	DNM1L	P49841	GSK3B	S544	A539V	539	Missense	distal	-5	no	6.419	6.721	EPSD	COSMIC	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	O00429	DNM1L	P49841	GSK3B	S544	Q545K	545	Missense	proximal	1	no	6.419	6.141	EPSD	COSMIC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	O00429	DNM1L	P49841	GSK3B	S544	S538N	538	Missense	distal	-6	no	6.419	6.417	EPSD	COSMIC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	O00429	DNM1L	P49841	GSK3B	S548	A543S	543	Missense	distal	-5	no	10.349	10.072	EPSD	COSMIC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	O00429	DNM1L	P49841	GSK3B	S548	Q545K	545	Missense	distal	-3	no	10.349	10.343	EPSD	COSMIC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	Q92908	GATA6	P49841	GSK3B	T62	A57D	57	Missense	distal	-5	no	8.268	8.263	EPSD	COSMIC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	Q92908	GATA6	P49841	GSK3B	S436	S437P	437	Missense	proximal	1	no	3.892	7.737	EPSD	COSMIC	6.007	Gain
CMGC_GSK_GSK3B_ST	Q92908	GATA6	P49841	GSK3B	T515	S518F	518	Missense	distal	3	no	8.408	8.198	EPSD	COSMIC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	Q92908	GATA6	P49841	GSK3B	S523	S518F	518	Missense	distal	-5	no	6.520	7.080	EPSD	COSMIC	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	Q92908	GATA6	P49841	GSK3B	S531	T537A	537	Missense	distal	6	no	8.241	8.238	EPSD	COSMIC;GDSC;CCLE	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	Q92908	GATA6	P49841	GSK3B	S531	S531Y	531	Missense	central	0	yes	8.241	0.000	EPSD	COSMIC	6.007	Loss
CMGC_GSK_GSK3B_ST	P17275	JUNB	P49841	GSK3B	S70	G73C	73	Missense	distal	3	no	8.426	8.167	EPSD	COSMIC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	P17275	JUNB	P49841	GSK3B	S70	D75N	75	Missense	distal	5	no	8.426	8.000	EPSD	COSMIC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	P17275	JUNB	P49841	GSK3B	S70	S74W	74	Missense	distal	4	no	8.426	4.477	EPSD	COSMIC	6.007	Loss
CMGC_GSK_GSK3B_ST	P17275	JUNB	P49841	GSK3B	T102	P103H	103	Missense	proximal	1	no	7.614	3.914	EPSD	COSMIC;GDSC;CCLE	6.007	Loss
CMGC_GSK_GSK3B_ST	P17275	JUNB	P49841	GSK3B	T102	N96T	96	Missense	distal	-6	no	7.614	7.558	EPSD	COSMIC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	P17275	JUNB	P49841	GSK3B	S251	R250L	250	Missense	proximal	-1	no	9.767	9.829	EPSD;PhosphoSitePlus	COSMIC	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	P17275	JUNB	P49841	GSK3B	T255	R250L	250	Missense	distal	-5	no	12.175	11.587	PhosphoSitePlus;EPSD	COSMIC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	P30304	CDC25A	P49841	GSK3B	S263	L264V	264	Missense	proximal	1	no	6.869	6.739	EPSD	COSMIC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	P30304	CDC25A	P49841	GSK3B	S263	R270Q	270	Missense	distal	7	no	6.869	6.521	EPSD	COSMIC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	P30304	CDC25A	P49841	GSK3B	S298	S293N	293	Missense	distal	-5	no	8.655	8.363	EPSD	COSMIC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	P30304	CDC25A	P49841	GSK3B	S317	P322L	322	Missense	distal	5	no	7.549	6.268	EPSD	COSMIC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	P30304	CDC25A	P49841	GSK3B	S317	S320Y	320	Missense	distal	3	no	7.549	7.126	EPSD	COSMIC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	P30304	CDC25A	P49841	GSK3B	S321	P322L	322	Missense	proximal	1	no	7.617	4.756	EPSD	COSMIC	6.007	Loss
CMGC_GSK_GSK3B_ST	P30304	CDC25A	P49841	GSK3B	S321	S320Y	320	Missense	proximal	-1	no	7.617	7.477	EPSD	COSMIC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	P30304	CDC25A	P49841	GSK3B	S505	S505R	505	Missense	central	0	yes	6.134	0.000	EPSD	COSMIC	6.007	Loss
CMGC_GSK_GSK3B_ST	P30304	CDC25A	P49841	GSK3B	S505	K500N	500	Missense	distal	-5	no	6.134	5.641	EPSD	COSMIC	6.007	Loss
CMGC_GSK_GSK3B_ST	Q9NRR4	DROSHA	P49841	GSK3B	S217	K214N	214	Missense	distal	-3	no	6.119	6.000	EPSD	COSMIC;GDSC;CCLE	6.007	Loss
CMGC_GSK_GSK3B_ST	Q9NRR4	DROSHA	P49841	GSK3B	S217	P211T	211	Missense	distal	-6	no	6.119	6.040	EPSD	COSMIC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	Q9NRR4	DROSHA	P49841	GSK3B	S217	P216A	216	Missense	proximal	-1	no	6.119	5.908	EPSD	COSMIC	6.007	Loss
CMGC_GSK_GSK3B_ST	Q9NRR4	DROSHA	P49841	GSK3B	S217	R219I	219	Missense	proximal	2	no	6.119	6.161	EPSD	COSMIC;GDSC;CCLE	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	Q9NRR4	DROSHA	P49841	GSK3B	S221	K214N	214	Missense	distal	-7	no	7.086	7.071	EPSD	COSMIC;GDSC;CCLE	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	Q9NRR4	DROSHA	P49841	GSK3B	S221	P216A	216	Missense	distal	-5	no	7.086	7.521	EPSD	COSMIC	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	Q9NRR4	DROSHA	P49841	GSK3B	S221	L225Q	225	Missense	distal	4	no	7.086	6.241	EPSD	COSMIC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	Q9NRR4	DROSHA	P49841	GSK3B	S221	R219I	219	Missense	proximal	-2	no	7.086	7.191	EPSD	COSMIC;GDSC;CCLE	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	Q9NRR4	DROSHA	P49841	GSK3B	S255	R254H	254	Missense	proximal	-1	no	7.174	7.260	EPSD	COSMIC	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	Q9NRR4	DROSHA	P49841	GSK3B	S255	E251G	251	Missense	distal	-4	no	7.174	7.343	EPSD	COSMIC	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	Q9NRR4	DROSHA	P49841	GSK3B	S255	R252Q	252	Missense	distal	-3	no	7.174	7.035	EPSD	COSMIC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	Q9NRR4	DROSHA	P49841	GSK3B	T274	R279C	279	Missense	distal	5	no	8.231	6.674	EPSD	COSMIC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	Q9NRR4	DROSHA	P49841	GSK3B	T274	R277C	277	Missense	distal	3	no	8.231	8.386	EPSD	COSMIC	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	Q9NRR4	DROSHA	P49841	GSK3B	T274	S276C	276	Missense	proximal	2	no	8.231	7.738	EPSD	COSMIC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	Q9NRR4	DROSHA	P49841	GSK3B	T274	R279H	279	Missense	distal	5	no	8.231	7.242	EPSD	COSMIC;GDSC;CCLE	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	Q9NRR4	DROSHA	P49841	GSK3B	T274	H278R	278	Missense	distal	4	no	8.231	8.949	EPSD	COSMIC	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	Q9NRR4	DROSHA	P49841	GSK3B	S276	R279C	279	Missense	distal	3	no	8.553	8.708	EPSD	COSMIC	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	Q9NRR4	DROSHA	P49841	GSK3B	S276	R277C	277	Missense	proximal	1	no	8.553	6.550	EPSD	COSMIC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	Q9NRR4	DROSHA	P49841	GSK3B	S276	S276C	276	Missense	central	0	yes	8.553	0.000	EPSD	COSMIC	6.007	Loss
CMGC_GSK_GSK3B_ST	Q9NRR4	DROSHA	P49841	GSK3B	S276	R279H	279	Missense	distal	3	no	8.553	8.895	EPSD	COSMIC;GDSC;CCLE	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	Q9NRR4	DROSHA	P49841	GSK3B	S276	H278R	278	Missense	proximal	2	no	8.553	8.896	EPSD	COSMIC	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	Q9NRR4	DROSHA	P49841	GSK3B	S284	R279C	279	Missense	distal	-5	no	6.751	6.573	EPSD	COSMIC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	Q9NRR4	DROSHA	P49841	GSK3B	S284	R277C	277	Missense	distal	-7	no	6.751	6.756	EPSD	COSMIC	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	Q9NRR4	DROSHA	P49841	GSK3B	S284	R279H	279	Missense	distal	-5	no	6.751	6.221	EPSD	COSMIC;GDSC;CCLE	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	Q9NRR4	DROSHA	P49841	GSK3B	S284	H278R	278	Missense	distal	-6	no	6.751	6.728	EPSD	COSMIC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	Q9NRR4	DROSHA	P49841	GSK3B	S300	S302C	302	Missense	proximal	2	no	9.866	9.374	EPSD;PhosphoSitePlus	COSMIC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	Q9NRR4	DROSHA	P49841	GSK3B	T330	P324S	324	Missense	distal	-6	no	6.832	6.811	EPSD	COSMIC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	Q9NRR4	DROSHA	P49841	GSK3B	T330	E332D	332	Missense	proximal	2	no	6.832	7.011	EPSD	COSMIC	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	Q9NRR4	DROSHA	P49841	GSK3B	S343	P347L	347	Missense	distal	4	no	6.425	6.678	EPSD	COSMIC	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	Q9NRR4	DROSHA	P49841	GSK3B	S343	I350M	350	Missense	distal	7	no	6.425	6.458	EPSD	COSMIC	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	Q9NRR4	DROSHA	P49841	GSK3B	S355	I350M	350	Missense	distal	-5	no	6.501	6.330	EPSD	COSMIC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	Q9NRR4	DROSHA	P49841	GSK3B	S373	D370N	370	Missense	distal	-3	no	6.783	6.643	EPSD	COSMIC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	Q9NRR4	DROSHA	P49841	GSK3B	S373	E366K	366	Missense	distal	-7	no	6.783	6.772	EPSD	COSMIC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	Q9NRR4	DROSHA	P49841	GSK3B	S373	E367K	367	Missense	distal	-6	no	6.783	6.782	EPSD	COSMIC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	Q9NRR4	DROSHA	P49841	GSK3B	S373	E368K	368	Missense	distal	-5	no	6.783	6.553	EPSD	COSMIC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	Q9NRR4	DROSHA	P49841	GSK3B	S424	N420H	420	Missense	distal	-4	no	5.817	6.027	EPSD	COSMIC	6.007	Gain
CMGC_GSK_GSK3B_ST	Q9NRR4	DROSHA	P49841	GSK3B	S491	E486K	486	Missense	distal	-5	no	7.852	7.622	EPSD	COSMIC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	Q9NRR4	DROSHA	P49841	GSK3B	T747	P749Q	749	Missense	proximal	2	no	6.272	6.051	EPSD	COSMIC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	Q9NRR4	DROSHA	P49841	GSK3B	T747	R753C	753	Missense	distal	6	no	6.272	6.264	EPSD	COSMIC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	Q9NRR4	DROSHA	P49841	GSK3B	T958	R961K	961	Missense	distal	3	no	6.513	6.757	EPSD	COSMIC	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	P15924	DSP	P49841	GSK3B	T59	G60S	60	Missense	proximal	1	no	7.837	7.186	EPSD	COSMIC;CCLE	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	P15924	DSP	P49841	GSK3B	S157	R162C	162	Missense	distal	5	no	6.169	4.613	EPSD	COSMIC;GDSC;CCLE	6.007	Loss
CMGC_GSK_GSK3B_ST	P15924	DSP	P49841	GSK3B	T634	P630T	630	Missense	distal	-4	no	6.647	6.875	EPSD	COSMIC;CCLE	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	P15924	DSP	P49841	GSK3B	T634	H632P	632	Missense	proximal	-2	no	6.647	7.009	EPSD	COSMIC	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	P15924	DSP	P49841	GSK3B	S2024	K2028N	2028	Missense	distal	4	no	7.352	6.944	EPSD	COSMIC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	P15924	DSP	P49841	GSK3B	S2041	S2044Y	2044	Missense	distal	3	no	8.396	7.973	EPSD	COSMIC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	P15924	DSP	P49841	GSK3B	S2549	F2543V	2543	Missense	distal	-6	no	6.507	6.494	EPSD	COSMIC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	P15924	DSP	P49841	GSK3B	S2549	K2542T	2542	Missense	distal	-7	no	6.507	6.513	EPSD	COSMIC	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	P15924	DSP	P49841	GSK3B	S2549	G2550D	2550	Missense	proximal	1	no	6.507	6.598	EPSD	COSMIC;GDSC;CCLE	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	P15924	DSP	P49841	GSK3B	S2551	G2550D	2550	Missense	proximal	-1	no	6.406	6.339	EPSD	COSMIC;GDSC;CCLE	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	P15924	DSP	P49841	GSK3B	S2594	I2596T	2596	Missense	proximal	2	no	6.223	6.289	EPSD	COSMIC	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	P15924	DSP	P49841	GSK3B	S2598	T2603I	2603	Missense	distal	5	no	6.965	6.321	EPSD	COSMIC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	P15924	DSP	P49841	GSK3B	S2598	I2596T	2596	Missense	proximal	-2	no	6.965	7.003	EPSD	COSMIC	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	P15924	DSP	P49841	GSK3B	T2612	S2606R	2606	Missense	distal	-6	no	7.690	7.633	EPSD	COSMIC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	P15924	DSP	P49841	GSK3B	T2612	I2619T	2619	Missense	distal	7	no	7.690	7.296	EPSD	COSMIC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	P15924	DSP	P49841	GSK3B	T2612	L2613M	2613	Missense	proximal	1	no	7.690	6.964	EPSD	COSMIC;CCLE	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	P15924	DSP	P49841	GSK3B	T2612	D2611E	2611	Missense	proximal	-1	no	7.690	7.739	EPSD	COSMIC	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	P15924	DSP	P49841	GSK3B	S2617	I2619T	2619	Missense	proximal	2	no	6.490	6.556	EPSD	COSMIC	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	P15924	DSP	P49841	GSK3B	S2617	L2613M	2613	Missense	distal	-4	no	6.490	6.781	EPSD	COSMIC;CCLE	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	P15924	DSP	P49841	GSK3B	S2617	D2611E	2611	Missense	distal	-6	no	6.490	6.454	EPSD	COSMIC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	P15924	DSP	P49841	GSK3B	S2815	M2819L	2819	Missense	distal	4	no	9.199	8.716	EPSD	COSMIC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	P15924	DSP	P49841	GSK3B	S2821	G2824R	2824	Missense	distal	3	no	7.158	6.743	EPSD	COSMIC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	P15924	DSP	P49841	GSK3B	S2821	R2826C	2826	Missense	distal	5	no	7.158	5.602	EPSD	COSMIC	6.007	Loss
CMGC_GSK_GSK3B_ST	P15924	DSP	P49841	GSK3B	S2821	M2819L	2819	Missense	proximal	-2	no	7.158	7.415	EPSD	COSMIC	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	P15924	DSP	P49841	GSK3B	S2825	G2824R	2824	Missense	proximal	-1	no	9.505	9.362	EPSD	COSMIC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	P15924	DSP	P49841	GSK3B	S2825	R2826C	2826	Missense	proximal	1	no	9.505	7.503	EPSD	COSMIC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	P15924	DSP	P49841	GSK3B	S2825	M2819L	2819	Missense	distal	-6	no	9.505	9.557	EPSD	COSMIC	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	P15924	DSP	P49841	GSK3B	S2827	G2824R	2824	Missense	distal	-3	no	7.990	8.163	EPSD	COSMIC	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	P15924	DSP	P49841	GSK3B	S2827	R2826C	2826	Missense	proximal	-1	no	7.990	8.092	EPSD	COSMIC	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	P15924	DSP	P49841	GSK3B	S2827	R2834C	2834	Missense	distal	7	no	7.990	7.945	EPSD	COSMIC;GDSC;CCLE	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	P15924	DSP	P49841	GSK3B	S2829	G2824R	2824	Missense	distal	-5	no	10.627	10.859	EPSD	COSMIC	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	P15924	DSP	P49841	GSK3B	S2829	R2826C	2826	Missense	distal	-3	no	10.627	10.562	EPSD	COSMIC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	P15924	DSP	P49841	GSK3B	S2829	R2834C	2834	Missense	distal	5	no	10.627	9.071	EPSD	COSMIC;GDSC;CCLE	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	P15924	DSP	P49841	GSK3B	S2829	S2835C	2835	Missense	distal	6	no	10.627	10.614	EPSD	COSMIC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	P15924	DSP	P49841	GSK3B	S2831	G2824R	2824	Missense	distal	-7	no	7.617	7.637	EPSD	COSMIC	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	P15924	DSP	P49841	GSK3B	S2831	R2826C	2826	Missense	distal	-5	no	7.617	7.439	EPSD	COSMIC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	P15924	DSP	P49841	GSK3B	S2831	R2834C	2834	Missense	distal	3	no	7.617	7.772	EPSD	COSMIC;GDSC;CCLE	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	P15924	DSP	P49841	GSK3B	S2831	S2835C	2835	Missense	distal	4	no	7.617	1.484	EPSD	COSMIC	6.007	Loss
CMGC_GSK_GSK3B_ST	P15924	DSP	P49841	GSK3B	S2833	R2826C	2826	Missense	distal	-7	no	9.890	9.894	EPSD	COSMIC	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	P15924	DSP	P49841	GSK3B	S2833	R2834C	2834	Missense	proximal	1	no	9.890	7.887	EPSD	COSMIC;GDSC;CCLE	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	P15924	DSP	P49841	GSK3B	S2833	S2835C	2835	Missense	proximal	2	no	9.890	9.398	EPSD	COSMIC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	P15924	DSP	P49841	GSK3B	S2835	R2834C	2834	Missense	proximal	-1	no	8.493	8.594	EPSD	COSMIC;GDSC;CCLE	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	P15924	DSP	P49841	GSK3B	S2835	S2835C	2835	Missense	central	0	yes	8.493	0.000	EPSD	COSMIC	6.007	Loss
CMGC_GSK_GSK3B_ST	P15924	DSP	P49841	GSK3B	S2837	G2844W	2844	Missense	distal	7	no	9.051	9.578	EPSD	COSMIC	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	P15924	DSP	P49841	GSK3B	S2837	R2834C	2834	Missense	distal	-3	no	9.051	8.986	EPSD	COSMIC;GDSC;CCLE	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	P15924	DSP	P49841	GSK3B	S2837	S2835C	2835	Missense	proximal	-2	no	9.051	8.739	EPSD	COSMIC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	P15924	DSP	P49841	GSK3B	S2839	G2844W	2844	Missense	distal	5	no	7.703	6.675	EPSD	COSMIC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	P15924	DSP	P49841	GSK3B	S2839	R2834C	2834	Missense	distal	-5	no	7.703	7.525	EPSD	COSMIC;GDSC;CCLE	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	P15924	DSP	P49841	GSK3B	S2839	S2835C	2835	Missense	distal	-4	no	7.703	5.589	EPSD	COSMIC	6.007	Loss
CMGC_GSK_GSK3B_ST	P15924	DSP	P49841	GSK3B	S2839	R2846W	2846	Missense	distal	7	no	7.703	7.812	EPSD	COSMIC	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	P15924	DSP	P49841	GSK3B	S2841	G2844W	2844	Missense	distal	3	no	9.923	9.767	EPSD	COSMIC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	P15924	DSP	P49841	GSK3B	S2841	R2834C	2834	Missense	distal	-7	no	9.923	9.927	EPSD	COSMIC;GDSC;CCLE	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	P15924	DSP	P49841	GSK3B	S2841	S2835C	2835	Missense	distal	-6	no	9.923	9.911	EPSD	COSMIC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	P15924	DSP	P49841	GSK3B	S2841	R2846W	2846	Missense	distal	5	no	9.923	8.621	EPSD	COSMIC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	P15924	DSP	P49841	GSK3B	S2845	G2844W	2844	Missense	proximal	-1	no	9.477	9.444	PhosphoSitePlus;EPSD	COSMIC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	P15924	DSP	P49841	GSK3B	S2845	R2846W	2846	Missense	proximal	1	no	9.477	9.694	PhosphoSitePlus;EPSD	COSMIC	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	P15924	DSP	P49841	GSK3B	S2849	G2844W	2844	Missense	distal	-5	no	6.665	6.640	EPSD;PhosphoSitePlus	COSMIC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	P15924	DSP	P49841	GSK3B	S2849	N2855I	2855	Missense	distal	6	no	6.665	6.671	EPSD;PhosphoSitePlus	COSMIC	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	P15924	DSP	P49841	GSK3B	S2849	R2846W	2846	Missense	distal	-3	no	6.665	6.595	EPSD;PhosphoSitePlus	COSMIC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	P15924	DSP	P49841	GSK3B	T2853	N2855I	2855	Missense	proximal	2	no	6.657	7.249	EPSD	COSMIC	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	P15924	DSP	P49841	GSK3B	T2853	R2846W	2846	Missense	distal	-7	no	6.657	6.667	EPSD	COSMIC	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	P15924	DSP	P49841	GSK3B	S2857	N2855I	2855	Missense	proximal	-2	no	7.059	7.277	EPSD	COSMIC	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	P15924	DSP	P49841	GSK3B	S2861	N2855I	2855	Missense	distal	-6	no	8.185	8.124	EPSD	COSMIC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	P15924	DSP	P49841	GSK3B	S2863	G2870E	2870	Missense	distal	7	no	7.467	7.487	EPSD	COSMIC	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	P60484	PTEN	P49841	GSK3B	S113	N117S	117	Missense	distal	4	no	3.292	6.902	EPSD	COSMIC	6.007	Gain
CMGC_GSK_GSK3B_ST	P60484	PTEN	P49841	GSK3B	S170	Q171P	171	Missense	proximal	1	no	4.212	7.481	EPSD	COSMIC	6.007	Gain
CMGC_GSK_GSK3B_ST	P60484	PTEN	P49841	GSK3B	S227	P231S	231	Missense	distal	4	no	3.999	6.970	EPSD	COSMIC	6.007	Gain
CMGC_GSK_GSK3B_ST	P60484	PTEN	P49841	GSK3B	S362	V369G	369	Missense	distal	7	no	9.223	8.818	EPSD;PhosphoSitePlus	COSMIC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	P60484	PTEN	P49841	GSK3B	S362	P357Q	357	Missense	distal	-5	no	9.223	9.523	EPSD;PhosphoSitePlus	COSMIC	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	P60484	PTEN	P49841	GSK3B	S362	V365I	365	Missense	distal	3	no	9.223	9.011	EPSD;PhosphoSitePlus	COSMIC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	P60484	PTEN	P49841	GSK3B	S362	P357L	357	Missense	distal	-5	no	9.223	9.489	EPSD;PhosphoSitePlus	COSMIC	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	P60484	PTEN	P49841	GSK3B	S362	P357S	357	Missense	distal	-5	no	9.223	9.380	EPSD;PhosphoSitePlus	COSMIC	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	P60484	PTEN	P49841	GSK3B	S362	S364C	364	Missense	proximal	2	no	9.223	8.731	EPSD;PhosphoSitePlus	COSMIC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	P60484	PTEN	P49841	GSK3B	S362	S361N	361	Missense	proximal	-1	no	9.223	9.285	EPSD;PhosphoSitePlus	COSMIC	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	P60484	PTEN	P49841	GSK3B	S362	E358D	358	Missense	distal	-4	no	9.223	9.220	EPSD;PhosphoSitePlus	COSMIC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	P60484	PTEN	P49841	GSK3B	T366	V369G	369	Missense	distal	3	no	10.540	10.792	PhosphoSitePlus;EPSD	COSMIC	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	P60484	PTEN	P49841	GSK3B	T366	V365I	365	Missense	proximal	-1	no	10.540	10.342	PhosphoSitePlus;EPSD	COSMIC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	P60484	PTEN	P49841	GSK3B	T366	S364C	364	Missense	proximal	-2	no	10.540	10.228	PhosphoSitePlus;EPSD	COSMIC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	P60484	PTEN	P49841	GSK3B	T366	S361N	361	Missense	distal	-5	no	10.540	10.248	PhosphoSitePlus;EPSD	COSMIC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	Q07812	BAX	P49841	GSK3B	S87	E90Q	90	Missense	distal	3	no	7.032	7.014	EPSD	COSMIC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	Q07812	BAX	P49841	GSK3B	S87	V83M	83	Missense	distal	-4	no	7.032	7.206	EPSD	COSMIC;GDSC	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	Q07812	BAX	P49841	GSK3B	S87	R89L	89	Missense	proximal	2	no	7.032	7.074	EPSD	COSMIC	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	Q07812	BAX	P49841	GSK3B	S163	P168R	168	Missense	distal	5	no	9.392	8.754	PhosphoSitePlus	COSMIC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	Q07812	BAX	P49841	GSK3B	S163	Y164H	164	Missense	proximal	1	no	9.392	9.010	PhosphoSitePlus	COSMIC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	P33076	CIITA	P49841	GSK3B	S280	G276D	276	Missense	distal	-4	no	6.911	6.739	EPSD	COSMIC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	P33076	CIITA	P49841	GSK3B	S280	G276V	276	Missense	distal	-4	no	6.911	6.105	EPSD	COSMIC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	P33076	CIITA	P49841	GSK3B	S280	P281L	281	Missense	proximal	1	no	6.911	4.050	EPSD	COSMIC	6.007	Loss
CMGC_GSK_GSK3B_ST	P33076	CIITA	P49841	GSK3B	S280	S286F	286	Missense	distal	6	no	6.911	6.899	EPSD	COSMIC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	P33076	CIITA	P49841	GSK3B	S280	S280Y	280	Missense	central	0	yes	6.911	0.000	EPSD	COSMIC	6.007	Loss
CMGC_GSK_GSK3B_ST	P33076	CIITA	P49841	GSK3B	S280	G276S	276	Missense	distal	-4	no	6.911	7.339	EPSD	COSMIC	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	P33076	CIITA	P49841	GSK3B	T287	A291S	291	Missense	distal	4	no	4.125	6.536	EPSD	COSMIC	6.007	Gain
CMGC_GSK_GSK3B_ST	P33076	CIITA	P49841	GSK3B	S288	A291S	291	Missense	distal	3	no	5.930	6.267	EPSD	COSMIC	6.007	Gain
CMGC_GSK_GSK3B_ST	P33076	CIITA	P49841	GSK3B	S373	E371D	371	Missense	proximal	-2	no	6.191	6.278	PhosphoSitePlus	COSMIC;GDSC;CCLE	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	P33076	CIITA	P49841	GSK3B	T740	R742K	742	Missense	proximal	2	no	7.825	7.759	EPSD	COSMIC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	P33076	CIITA	P49841	GSK3B	T740	L739F	739	Missense	proximal	-1	no	7.825	7.769	EPSD	COSMIC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	P33076	CIITA	P49841	GSK3B	T740	L733P	733	Missense	distal	-7	no	7.825	7.823	EPSD	COSMIC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	P33076	CIITA	P49841	GSK3B	T740	P734R	734	Missense	distal	-6	no	7.825	7.747	EPSD	COSMIC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	P33076	CIITA	P49841	GSK3B	T740	R745K	745	Missense	distal	5	no	7.825	6.950	EPSD	COSMIC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	P33076	CIITA	P49841	GSK3B	S834	R832C	832	Missense	proximal	-2	no	6.984	6.788	EPSD	COSMIC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	P33076	CIITA	P49841	GSK3B	S834	G831D	831	Missense	distal	-3	no	6.984	7.034	EPSD	COSMIC	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	P33076	CIITA	P49841	GSK3B	S944	G949E	949	Missense	distal	5	no	6.146	6.412	EPSD	COSMIC	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	P33076	CIITA	P49841	GSK3B	S1023	N1025T	1025	Missense	proximal	2	no	5.492	6.150	EPSD	COSMIC	6.007	Gain
CMGC_GSK_GSK3B_ST	P33076	CIITA	P49841	GSK3B	S1023	I1027M	1027	Missense	distal	4	no	5.492	6.579	EPSD	COSMIC	6.007	Gain
CMGC_GSK_GSK3B_ST	P33076	CIITA	P49841	GSK3B	S1023	I1027T	1027	Missense	distal	4	no	5.492	7.945	EPSD	COSMIC;GDSC;CCLE	6.007	Gain
CMGC_GSK_GSK3B_ST	Q14103	HNRNPD	P49841	GSK3B	S83	S87F	87	Missense	distal	4	no	11.052	7.438	PhosphoSitePlus	COSMIC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	Q14103	HNRNPD	P49841	GSK3B	S87	S87F	87	Missense	central	0	yes	6.223	0.000	EPSD	COSMIC	6.007	Loss
CMGC_GSK_GSK3B_ST	Q14103	HNRNPD	P49841	GSK3B	T91	S87F	87	Missense	distal	-4	no	6.257	5.103	EPSD	COSMIC	6.007	Loss
CMGC_GSK_GSK3B_ST	Q14103	HNRNPD	P49841	GSK3B	S190	P194H	194	Missense	distal	4	no	6.370	5.586	EPSD	COSMIC	6.007	Loss
CMGC_GSK_GSK3B_ST	Q14103	HNRNPD	P49841	GSK3B	S190	F185L	185	Missense	distal	-5	no	6.370	5.920	EPSD	COSMIC	6.007	Loss
CMGC_GSK_GSK3B_ST	Q14103	HNRNPD	P49841	GSK3B	S190	G187V	187	Missense	distal	-3	no	6.370	6.542	EPSD	COSMIC	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	P23246	SFPQ	P49841	GSK3B	S33	R32P	32	Missense	proximal	-1	no	6.095	6.288	EPSD	COSMIC	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	P23246	SFPQ	P49841	GSK3B	T177	G182R	182	Missense	distal	5	no	6.783	7.057	EPSD	COSMIC	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	P23246	SFPQ	P49841	GSK3B	S283	R287S	287	Missense	distal	4	no	4.835	7.873	EPSD	COSMIC	6.007	Gain
CMGC_GSK_GSK3B_ST	P23246	SFPQ	P49841	GSK3B	S379	N377K	377	Missense	proximal	-2	no	8.533	8.627	EPSD	COSMIC	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	P23246	SFPQ	P49841	GSK3B	S379	R376L	376	Missense	distal	-3	no	8.533	8.373	EPSD	COSMIC;CCLE	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	P23246	SFPQ	P49841	GSK3B	S379	R376C	376	Missense	distal	-3	no	8.533	8.468	EPSD	COSMIC;CCLE	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	P23246	SFPQ	P49841	GSK3B	T440	P444S	444	Missense	distal	4	no	3.316	6.287	EPSD	COSMIC;GDSC	6.007	Gain
CMGC_GSK_GSK3B_ST	P23246	SFPQ	P49841	GSK3B	T687	P680L	680	Missense	distal	-7	no	7.106	7.108	PhosphoSitePlus	COSMIC	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	Q96KS0	EGLN2	P49841	GSK3B	S74	G79S	79	Missense	distal	5	no	8.306	8.264	EPSD	COSMIC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	Q96KS0	EGLN2	P49841	GSK3B	S130	A128D	128	Missense	proximal	-2	no	8.108	8.427	EPSD	COSMIC	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	Q96KS0	EGLN2	P49841	GSK3B	S130	P129L	129	Missense	proximal	-1	no	8.108	7.977	EPSD	COSMIC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	Q96KS0	EGLN2	P49841	GSK3B	S401	P403Q	403	Missense	proximal	2	no	9.225	9.004	PhosphoSitePlus;EPSD	COSMIC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	Q96KS0	EGLN2	P49841	GSK3B	S401	T405M	405	Missense	distal	4	no	9.225	7.860	PhosphoSitePlus;EPSD	COSMIC;GDSC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	Q9UKA4	AKAP11	P49841	GSK3B	S29	S26C	26	Missense	distal	-3	no	7.135	7.238	EPSD	COSMIC	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	Q9UKA4	AKAP11	P49841	GSK3B	S267	I272V	272	Missense	distal	5	no	5.939	6.104	EPSD	COSMIC	6.007	Gain
CMGC_GSK_GSK3B_ST	Q9UKA4	AKAP11	P49841	GSK3B	T269	I272V	272	Missense	distal	3	no	7.843	8.056	EPSD	COSMIC	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	Q9UKA4	AKAP11	P49841	GSK3B	T269	W276C	276	Missense	distal	7	no	7.843	7.689	EPSD	COSMIC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	Q9UKA4	AKAP11	P49841	GSK3B	S273	I272V	272	Missense	proximal	-1	no	6.050	6.248	EPSD	COSMIC	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	Q9UKA4	AKAP11	P49841	GSK3B	S273	W276C	276	Missense	distal	3	no	6.050	5.947	EPSD	COSMIC	6.007	Loss
CMGC_GSK_GSK3B_ST	Q9UKA4	AKAP11	P49841	GSK3B	S288	D291N	291	Missense	distal	3	no	8.102	8.056	EPSD	COSMIC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	Q9UKA4	AKAP11	P49841	GSK3B	S422	D429A	429	Missense	distal	7	no	5.739	6.032	EPSD	COSMIC	6.007	Gain
CMGC_GSK_GSK3B_ST	Q9UKA4	AKAP11	P49841	GSK3B	S433	D429A	429	Missense	distal	-4	no	7.168	6.609	EPSD	COSMIC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	Q9UKA4	AKAP11	P49841	GSK3B	S448	S452F	452	Missense	distal	4	no	11.396	7.782	EPSD	COSMIC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	Q9UKA4	AKAP11	P49841	GSK3B	S448	S453F	453	Missense	distal	5	no	11.396	10.729	EPSD	COSMIC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	Q9UKA4	AKAP11	P49841	GSK3B	S452	S452F	452	Missense	central	0	yes	7.451	0.000	EPSD	COSMIC	6.007	Loss
CMGC_GSK_GSK3B_ST	Q9UKA4	AKAP11	P49841	GSK3B	S452	P457L	457	Missense	distal	5	no	7.451	6.170	EPSD	COSMIC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	Q9UKA4	AKAP11	P49841	GSK3B	S452	S453F	453	Missense	proximal	1	no	7.451	7.064	EPSD	COSMIC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	Q9UKA4	AKAP11	P49841	GSK3B	S456	S452F	452	Missense	distal	-4	no	7.411	6.257	EPSD	COSMIC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	Q9UKA4	AKAP11	P49841	GSK3B	S456	P457L	457	Missense	proximal	1	no	7.411	4.550	EPSD	COSMIC	6.007	Loss
CMGC_GSK_GSK3B_ST	Q9UKA4	AKAP11	P49841	GSK3B	S456	S453F	453	Missense	distal	-3	no	7.411	7.478	EPSD	COSMIC	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	Q9UKA4	AKAP11	P49841	GSK3B	T588	S589P	589	Missense	proximal	1	no	2.546	6.391	EPSD	COSMIC	6.007	Gain
CMGC_GSK_GSK3B_ST	Q9UKA4	AKAP11	P49841	GSK3B	T915	P917A	917	Missense	proximal	2	no	8.349	7.913	EPSD	COSMIC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	Q9UKA4	AKAP11	P49841	GSK3B	S970	V966A	966	Missense	distal	-4	no	6.628	6.702	EPSD	COSMIC	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	Q9UKA4	AKAP11	P49841	GSK3B	S1019	M1014V	1014	Missense	distal	-5	no	6.011	6.289	EPSD	COSMIC	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	Q9UKA4	AKAP11	P49841	GSK3B	S1019	V1015I	1015	Missense	distal	-4	no	6.011	4.761	EPSD	COSMIC	6.007	Loss
CMGC_GSK_GSK3B_ST	Q9UKA4	AKAP11	P49841	GSK3B	T1100	N1095S	1095	Missense	distal	-5	no	9.354	9.646	EPSD	COSMIC;CCLE	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	Q9UKA4	AKAP11	P49841	GSK3B	S1103	R1110L	1110	Missense	distal	7	no	6.647	6.195	EPSD	COSMIC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	Q9UKA4	AKAP11	P49841	GSK3B	T1104	R1110L	1110	Missense	distal	6	no	7.658	7.657	EPSD	COSMIC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	Q9UKA4	AKAP11	P49841	GSK3B	S1109	R1110L	1110	Missense	proximal	1	no	7.499	6.958	EPSD	COSMIC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	Q9UKA4	AKAP11	P49841	GSK3B	T1136	E1131D	1131	Missense	distal	-5	no	10.135	9.977	PhosphoSitePlus;EPSD	COSMIC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	Q9UKA4	AKAP11	P49841	GSK3B	T1140	S1144L	1144	Missense	distal	4	no	9.758	7.040	EPSD;PhosphoSitePlus	COSMIC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	Q9UKA4	AKAP11	P49841	GSK3B	T1140	V1146I	1146	Missense	distal	6	no	9.758	9.768	EPSD;PhosphoSitePlus	COSMIC	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	Q9UKA4	AKAP11	P49841	GSK3B	S1144	S1144L	1144	Missense	central	0	yes	6.613	0.000	EPSD	COSMIC	6.007	Loss
CMGC_GSK_GSK3B_ST	Q9UKA4	AKAP11	P49841	GSK3B	S1144	V1146I	1146	Missense	proximal	2	no	6.613	6.942	EPSD	COSMIC	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	Q9UKA4	AKAP11	P49841	GSK3B	S1452	Y1455H	1455	Missense	distal	3	no	5.665	6.058	EPSD	COSMIC	6.007	Gain
CMGC_GSK_GSK3B_ST	Q9UKA4	AKAP11	P49841	GSK3B	S1452	T1459A	1459	Missense	distal	7	no	5.665	6.071	EPSD	COSMIC	6.007	Gain
CMGC_GSK_GSK3B_ST	Q9UKA4	AKAP11	P49841	GSK3B	S1456	S1452C	1452	Missense	distal	-4	no	7.335	5.221	EPSD	COSMIC	6.007	Loss
CMGC_GSK_GSK3B_ST	Q9UKA4	AKAP11	P49841	GSK3B	S1456	Y1455H	1455	Missense	proximal	-1	no	7.335	7.424	EPSD	COSMIC	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	Q9UKA4	AKAP11	P49841	GSK3B	S1456	T1459A	1459	Missense	distal	3	no	7.335	7.031	EPSD	COSMIC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	Q9UKA4	AKAP11	P49841	GSK3B	S1460	Y1455H	1455	Missense	distal	-5	no	7.045	6.559	EPSD	COSMIC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	Q9UKA4	AKAP11	P49841	GSK3B	S1460	T1459A	1459	Missense	proximal	-1	no	7.045	6.965	EPSD	COSMIC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	Q9UKA4	AKAP11	P49841	GSK3B	S1483	S1476C	1476	Missense	distal	-7	no	6.866	6.889	EPSD	COSMIC	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	Q9UKA4	AKAP11	P49841	GSK3B	S1611	R1608G	1608	Missense	distal	-3	no	7.659	7.487	EPSD	COSMIC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	Q9UKA4	AKAP11	P49841	GSK3B	S1615	R1608G	1608	Missense	distal	-7	no	7.370	7.349	EPSD	COSMIC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	Q9UKA4	AKAP11	P49841	GSK3B	S1683	E1686K	1686	Missense	distal	3	no	6.249	6.141	EPSD	COSMIC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	Q9NW38	FANCL	P49841	GSK3B	S77	P78S	78	Missense	proximal	1	no	8.094	4.249	EPSD	COSMIC	6.007	Loss
CMGC_GSK_GSK3B_ST	Q9NW38	FANCL	P49841	GSK3B	S77	M74I	74	Missense	distal	-3	no	8.094	8.235	EPSD	COSMIC;GDSC;CCLE	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	Q9NW38	FANCL	P49841	GSK3B	T178	A175V	175	Missense	distal	-3	no	8.636	8.783	PhosphoSitePlus	COSMIC	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	Q9NW38	FANCL	P49841	GSK3B	T178	S181T	181	Missense	distal	3	no	8.636	8.604	PhosphoSitePlus	COSMIC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	P56524	HDAC4	P49841	GSK3B	S210	S210F	210	Missense	central	0	yes	9.356	0.000	EPSD	COSMIC	6.007	Loss
CMGC_GSK_GSK3B_ST	P56524	HDAC4	P49841	GSK3B	S210	P216L	216	Missense	distal	6	no	9.356	9.349	EPSD	COSMIC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	P56524	HDAC4	P49841	GSK3B	S210	T206M	206	Missense	distal	-4	no	9.356	8.632	EPSD	COSMIC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	P56524	HDAC4	P49841	GSK3B	S215	G220R	220	Missense	distal	5	no	10.763	11.037	EPSD	COSMIC;GDSC	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	P56524	HDAC4	P49841	GSK3B	S215	S210F	210	Missense	distal	-5	no	10.763	11.323	EPSD	COSMIC	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	P56524	HDAC4	P49841	GSK3B	S215	P216L	216	Missense	proximal	1	no	10.763	7.903	EPSD	COSMIC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	P56524	HDAC4	P49841	GSK3B	S215	G220V	220	Missense	distal	5	no	10.763	10.220	EPSD	COSMIC;CCLE	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	P56524	HDAC4	P49841	GSK3B	S219	G220R	220	Missense	proximal	1	no	6.001	6.876	EPSD	COSMIC;GDSC	6.007	Gain
CMGC_GSK_GSK3B_ST	P56524	HDAC4	P49841	GSK3B	S219	P216L	216	Missense	distal	-3	no	6.001	6.128	EPSD	COSMIC	6.007	Gain
CMGC_GSK_GSK3B_ST	P56524	HDAC4	P49841	GSK3B	S219	G220V	220	Missense	proximal	1	no	6.001	6.205	EPSD	COSMIC;CCLE	6.007	Gain
CMGC_GSK_GSK3B_ST	P56524	HDAC4	P49841	GSK3B	S224	P228S	228	Missense	distal	4	no	3.580	6.551	EPSD	COSMIC	6.007	Gain
CMGC_GSK_GSK3B_ST	P56524	HDAC4	P49841	GSK3B	S266	L268F	268	Missense	proximal	2	no	6.769	6.365	EPSD	COSMIC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	P56524	HDAC4	P49841	GSK3B	S266	R270L	270	Missense	distal	4	no	6.769	7.089	EPSD	COSMIC	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	P56524	HDAC4	P49841	GSK3B	S266	K259R	259	Missense	distal	-7	no	6.769	6.766	EPSD	COSMIC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	P56524	HDAC4	P49841	GSK3B	S294	C292W	292	Missense	proximal	-2	no	8.269	8.671	EPSD	COSMIC	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	P56524	HDAC4	P49841	GSK3B	S294	S294G	294	Missense	central	0	yes	8.269	0.000	EPSD	COSMIC	6.007	Loss
CMGC_GSK_GSK3B_ST	P56524	HDAC4	P49841	GSK3B	S298	C292W	292	Missense	distal	-6	no	10.108	10.090	EPSD;PhosphoSitePlus	COSMIC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	P56524	HDAC4	P49841	GSK3B	S298	S294G	294	Missense	distal	-4	no	10.108	9.680	EPSD;PhosphoSitePlus	COSMIC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	P56524	HDAC4	P49841	GSK3B	S307	S311I	311	Missense	distal	4	no	6.805	3.483	EPSD	COSMIC	6.007	Loss
CMGC_GSK_GSK3B_ST	P56524	HDAC4	P49841	GSK3B	S328	L333P	333	Missense	distal	5	no	4.832	6.112	EPSD	COSMIC;GDSC;CCLE	6.007	Gain
CMGC_GSK_GSK3B_ST	P56524	HDAC4	P49841	GSK3B	S348	A341S	341	Missense	distal	-7	no	6.267	6.245	EPSD	COSMIC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	P56524	HDAC4	P49841	GSK3B	S348	P352S	352	Missense	distal	4	no	6.267	9.238	EPSD	COSMIC	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	P56524	HDAC4	P49841	GSK3B	S348	P344L	344	Missense	distal	-4	no	6.267	5.481	EPSD	COSMIC	6.007	Loss
CMGC_GSK_GSK3B_ST	P56524	HDAC4	P49841	GSK3B	S348	Y346C	346	Missense	proximal	-2	no	6.267	6.275	EPSD	COSMIC	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	P56524	HDAC4	P49841	GSK3B	T394	L387P	387	Missense	distal	-7	no	9.322	9.320	EPSD	COSMIC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	P56524	HDAC4	P49841	GSK3B	S400	R404Q	404	Missense	distal	4	no	7.430	6.905	EPSD	COSMIC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	P56524	HDAC4	P49841	GSK3B	S400	G407V	407	Missense	distal	7	no	7.430	7.836	EPSD	COSMIC	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	P56524	HDAC4	P49841	GSK3B	S628	G623C	623	Missense	distal	-5	no	8.322	8.376	EPSD	COSMIC	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	P56524	HDAC4	P49841	GSK3B	S628	A635T	635	Missense	distal	7	no	8.322	7.916	EPSD	COSMIC;CCLE	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	P56524	HDAC4	P49841	GSK3B	S628	R629Q	629	Missense	proximal	1	no	8.322	7.374	EPSD	COSMIC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	P56524	HDAC4	P49841	GSK3B	S633	A635T	635	Missense	proximal	2	no	8.220	8.338	EPSD	COSMIC;CCLE	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	P56524	HDAC4	P49841	GSK3B	S633	R629Q	629	Missense	distal	-4	no	8.220	8.577	EPSD	COSMIC	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	P56524	HDAC4	P49841	GSK3B	S642	P646S	646	Missense	distal	4	no	5.250	8.221	EPSD	COSMIC	6.007	Gain
CMGC_GSK_GSK3B_ST	Q92993	KAT5	P49841	GSK3B	S86	G82E	82	Missense	distal	-4	no	8.784	8.615	PhosphoSitePlus;EPSD	COSMIC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	Q92993	KAT5	P49841	GSK3B	S98	A101D	101	Missense	distal	3	no	5.973	6.405	EPSD	COSMIC;CCLE	6.007	Gain
CMGC_GSK_GSK3B_ST	Q92993	KAT5	P49841	GSK3B	S102	P109L	109	Missense	distal	7	no	6.949	6.998	EPSD	COSMIC	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	Q92993	KAT5	P49841	GSK3B	S102	I108V	108	Missense	distal	6	no	6.949	6.940	EPSD	COSMIC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	Q92993	KAT5	P49841	GSK3B	S102	A101D	101	Missense	proximal	-1	no	6.949	7.044	EPSD	COSMIC;CCLE	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	Q92993	KAT5	P49841	GSK3B	S155	V160M	160	Missense	distal	5	no	5.846	6.208	EPSD	COSMIC	6.007	Gain
CMGC_GSK_GSK3B_ST	Q92993	KAT5	P49841	GSK3B	T158	V160M	160	Missense	proximal	2	no	8.912	8.610	EPSD	COSMIC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	Q92993	KAT5	P49841	GSK3B	T158	S155L	155	Missense	distal	-3	no	8.912	8.921	EPSD	COSMIC	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	Q92993	KAT5	P49841	GSK3B	T158	V153M	153	Missense	distal	-5	no	8.912	8.634	EPSD	COSMIC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	Q92993	KAT5	P49841	GSK3B	T195	Q200H	200	Missense	distal	5	no	6.036	5.386	EPSD	COSMIC	6.007	Loss
CMGC_GSK_GSK3B_ST	Q92993	KAT5	P49841	GSK3B	T195	S190L	190	Missense	distal	-5	no	6.036	6.145	EPSD	COSMIC	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	Q92993	KAT5	P49841	GSK3B	T195	R188Q	188	Missense	distal	-7	no	6.036	6.033	EPSD	COSMIC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	Q92993	KAT5	P49841	GSK3B	T195	R188P	188	Missense	distal	-7	no	6.036	6.016	EPSD	COSMIC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	Q92993	KAT5	P49841	GSK3B	S199	Q200H	200	Missense	proximal	1	no	7.487	7.055	EPSD	COSMIC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	Q92993	KAT5	P49841	GSK3B	S199	D204N	204	Missense	distal	5	no	7.487	7.061	EPSD	COSMIC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	O95997	PTTG1	P49841	GSK3B	S165	L161M	161	Missense	distal	-4	no	7.639	7.929	EPSD	COSMIC	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	O95997	PTTG1	P49841	GSK3B	S165	P163S	163	Missense	proximal	-2	no	7.639	7.382	EPSD	COSMIC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	O95997	PTTG1	P49841	GSK3B	S165	M169T	169	Missense	distal	4	no	7.639	9.005	EPSD	COSMIC;GDSC;CCLE	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	O95997	PTTG1	P49841	GSK3B	S171	M169T	169	Missense	proximal	-2	no	7.768	8.126	EPSD	COSMIC;GDSC;CCLE	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	P14618	PKM	P49841	GSK3B	S6	A11V	11	Missense	distal	5	no	6.814	6.388	EPSD	COSMIC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	P14618	PKM	P49841	GSK3B	S6	G9R	9	Missense	distal	3	no	6.814	6.400	EPSD	COSMIC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	P14618	PKM	P49841	GSK3B	S37	R32L	32	Missense	distal	-5	no	9.277	8.689	EPSD	COSMIC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	P14618	PKM	P49841	GSK3B	T93	A94V	94	Missense	proximal	1	no	5.276	6.017	EPSD	COSMIC	6.007	Gain
CMGC_GSK_GSK3B_ST	P14618	PKM	P49841	GSK3B	S406	P403T	403	Missense	distal	-3	no	6.023	6.165	EPSD	COSMIC	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	P14618	PKM	P49841	GSK3B	S406	D407N	407	Missense	proximal	1	no	6.023	3.607	EPSD	COSMIC	6.007	Loss
CMGC_GSK_GSK3B_ST	P14618	PKM	P49841	GSK3B	S406	D407H	407	Missense	proximal	1	no	6.023	5.426	EPSD	COSMIC	6.007	Loss
CMGC_GSK_GSK3B_ST	P14618	PKM	P49841	GSK3B	S406	R400H	400	Missense	distal	-6	no	6.023	6.047	EPSD	COSMIC	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	P14618	PKM	P49841	GSK3B	S406	A413T	413	Missense	distal	7	no	6.023	5.617	EPSD	COSMIC;GDSC;CCLE	6.007	Loss
CMGC_GSK_GSK3B_ST	P14618	PKM	P49841	GSK3B	S406	T409A	409	Missense	distal	3	no	6.023	5.719	EPSD	COSMIC	6.007	Loss
CMGC_GSK_GSK3B_ST	P49841	GSK3B	P49841	GSK3B	S9	S9F	9	Missense	central	0	yes	6.632	0.000	EPSD	COSMIC	6.007	Loss
CMGC_GSK_GSK3B_ST	P49841	GSK3B	P49841	GSK3B	S9	P16A	16	Missense	distal	7	no	6.632	7.043	EPSD	COSMIC	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	P49841	GSK3B	P49841	GSK3B	S9	S2P	2	Missense	distal	-7	no	6.632	6.630	EPSD	COSMIC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	P49841	GSK3B	P49841	GSK3B	S25	D31Y	31	Missense	distal	6	no	6.701	6.703	EPSD	COSMIC	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	P49841	GSK3B	P49841	GSK3B	S25	S25C	25	Missense	central	0	yes	6.701	0.000	EPSD	COSMIC	6.007	Loss
CMGC_GSK_GSK3B_ST	P49841	GSK3B	P49841	GSK3B	S25	A22T	22	Missense	distal	-3	no	6.701	6.706	EPSD	COSMIC	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	P49841	GSK3B	P49841	GSK3B	T43	G47C	47	Missense	distal	4	no	7.636	4.746	EPSD;PhosphoSitePlus	COSMIC	6.007	Loss
CMGC_GSK_GSK3B_ST	P49841	GSK3B	P49841	GSK3B	T43	V41G	41	Missense	proximal	-2	no	7.636	7.551	EPSD;PhosphoSitePlus	COSMIC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	P49841	GSK3B	P49841	GSK3B	T43	V37G	37	Missense	distal	-6	no	7.636	7.720	EPSD;PhosphoSitePlus	COSMIC	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	P49841	GSK3B	P49841	GSK3B	S215	Y222C	222	Missense	distal	7	no	7.507	7.457	EPSD	COSMIC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	P49841	GSK3B	P49841	GSK3B	S219	Y222C	222	Missense	distal	3	no	6.818	7.025	EPSD	COSMIC	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	P49841	GSK3B	P49841	GSK3B	T275	R278M	278	Missense	distal	3	no	7.582	7.762	EPSD	COSMIC	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	P49841	GSK3B	P49841	GSK3B	T390	A397V	397	Missense	distal	7	no	5.963	6.041	PhosphoSitePlus;EPSD	COSMIC;CCLE	6.007	Gain
CMGC_GSK_GSK3B_ST	Q96R06	SPAG5	P49841	GSK3B	S39	N38S	38	Missense	proximal	-1	no	6.758	6.696	EPSD	COSMIC;GDSC;CCLE	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	Q96R06	SPAG5	P49841	GSK3B	S43	N38S	38	Missense	distal	-5	no	8.603	8.895	EPSD	COSMIC;GDSC;CCLE	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	Q96R06	SPAG5	P49841	GSK3B	S66	N73S	73	Missense	distal	7	no	6.872	6.749	EPSD	COSMIC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	Q96R06	SPAG5	P49841	GSK3B	T76	D77G	77	Missense	proximal	1	no	6.777	6.686	EPSD	COSMIC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	Q96R06	SPAG5	P49841	GSK3B	T76	N73S	73	Missense	distal	-3	no	6.777	6.871	EPSD	COSMIC	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	Q96R06	SPAG5	P49841	GSK3B	T76	H82R	82	Missense	distal	6	no	6.777	6.782	EPSD	COSMIC	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	Q96R06	SPAG5	P49841	GSK3B	S110	T114M	114	Missense	distal	4	no	6.052	4.686	EPSD	COSMIC	6.007	Loss
CMGC_GSK_GSK3B_ST	Q96R06	SPAG5	P49841	GSK3B	T111	T114M	114	Missense	distal	3	no	10.369	10.210	EPSD;PhosphoSitePlus	COSMIC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	Q96R06	SPAG5	P49841	GSK3B	S135	V131A	131	Missense	distal	-4	no	5.993	6.067	EPSD	COSMIC	6.007	Gain
CMGC_GSK_GSK3B_ST	Q96R06	SPAG5	P49841	GSK3B	S205	P198S	198	Missense	distal	-7	no	6.983	6.984	EPSD	COSMIC	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	Q96R06	SPAG5	P49841	GSK3B	S205	L201V	201	Missense	distal	-4	no	6.983	7.099	EPSD	COSMIC;CCLE	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	Q96R06	SPAG5	P49841	GSK3B	S341	K348E	348	Missense	distal	7	no	6.054	6.162	EPSD	COSMIC;GDSC;CCLE	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	Q96R06	SPAG5	P49841	GSK3B	S341	D335N	335	Missense	distal	-6	no	6.054	6.076	EPSD	COSMIC	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	Q96R06	SPAG5	P49841	GSK3B	T377	R370W	370	Missense	distal	-7	no	6.240	6.250	EPSD	COSMIC	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	Q96R06	SPAG5	P49841	GSK3B	S397	E395K	395	Missense	proximal	-2	no	6.387	6.356	EPSD	COSMIC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	Q96R06	SPAG5	P49841	GSK3B	S411	G407D	407	Missense	distal	-4	no	6.282	6.109	EPSD	COSMIC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	Q96R06	SPAG5	P49841	GSK3B	T466	T466I	466	Missense	central	0	yes	6.440	0.000	EPSD	COSMIC;GDSC;CCLE	6.007	Loss
CMGC_GSK_GSK3B_ST	Q96R06	SPAG5	P49841	GSK3B	T466	A460T	460	Missense	distal	-6	no	6.440	6.371	EPSD	COSMIC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	Q96R06	SPAG5	P49841	GSK3B	T656	W655R	655	Missense	proximal	-1	no	6.589	6.477	EPSD	COSMIC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	Q96R06	SPAG5	P49841	GSK3B	T937	P938L	938	Missense	proximal	1	no	6.516	3.656	EPSD;PhosphoSitePlus	COSMIC	6.007	Loss
CMGC_GSK_GSK3B_ST	Q96R06	SPAG5	P49841	GSK3B	S957	A961T	961	Missense	distal	4	no	4.513	6.056	EPSD	COSMIC	6.007	Gain
CMGC_GSK_GSK3B_ST	Q96R06	SPAG5	P49841	GSK3B	T963	A961T	961	Missense	proximal	-2	no	6.325	6.687	EPSD	COSMIC	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	Q96R06	SPAG5	P49841	GSK3B	T963	M966I	966	Missense	distal	3	no	6.325	6.095	EPSD	COSMIC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	O60341	KDM1A	P49841	GSK3B	S31	S35F	35	Missense	distal	4	no	6.838	3.223	EPSD	COSMIC	6.007	Loss
CMGC_GSK_GSK3B_ST	O60341	KDM1A	P49841	GSK3B	T305	A309S	309	Missense	distal	4	no	5.285	7.697	EPSD	COSMIC	6.007	Gain
CMGC_GSK_GSK3B_ST	O60341	KDM1A	P49841	GSK3B	T305	A309T	309	Missense	distal	4	no	5.285	6.828	EPSD	COSMIC	6.007	Gain
CMGC_GSK_GSK3B_ST	O60341	KDM1A	P49841	GSK3B	S683	R688K	688	Missense	distal	5	no	8.685	7.810	PhosphoSitePlus	COSMIC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	O60341	KDM1A	P49841	GSK3B	S683	T684M	684	Missense	proximal	1	no	8.685	8.289	PhosphoSitePlus	COSMIC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	Q9Y2X9	ZNF281	P49841	GSK3B	S16	S16R	16	Missense	central	0	yes	6.325	0.000	EPSD	COSMIC	6.007	Loss
CMGC_GSK_GSK3B_ST	Q9Y2X9	ZNF281	P49841	GSK3B	S160	A154T	154	Missense	distal	-6	no	7.051	6.982	EPSD	COSMIC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	Q9Y2X9	ZNF281	P49841	GSK3B	S255	S255F	255	Missense	central	0	yes	8.769	0.000	EPSD	COSMIC	6.007	Loss
CMGC_GSK_GSK3B_ST	Q9Y2X9	ZNF281	P49841	GSK3B	S255	D248N	248	Missense	distal	-7	no	8.769	8.772	EPSD	COSMIC	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	Q9Y2X9	ZNF281	P49841	GSK3B	S255	I253V	253	Missense	proximal	-2	no	8.769	8.747	EPSD	COSMIC;CCLE	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	Q9Y2X9	ZNF281	P49841	GSK3B	S638	H636L	636	Missense	proximal	-2	no	7.944	7.975	PhosphoSitePlus	COSMIC	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	Q9Y2X9	ZNF281	P49841	GSK3B	S638	R632P	632	Missense	distal	-6	no	7.944	8.022	PhosphoSitePlus	COSMIC;GDSC;CCLE	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	Q9Y2X9	ZNF281	P49841	GSK3B	S638	T637I	637	Missense	proximal	-1	no	7.944	7.870	PhosphoSitePlus	COSMIC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	Q9Y2X9	ZNF281	P49841	GSK3B	S651	G653S	653	Missense	proximal	2	no	7.208	7.466	EPSD	COSMIC	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	Q9Y2X9	ZNF281	P49841	GSK3B	S651	Q655E	655	Missense	distal	4	no	7.208	8.750	EPSD	COSMIC	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	Q9Y2X9	ZNF281	P49841	GSK3B	S651	L650F	650	Missense	proximal	-1	no	7.208	7.152	EPSD	COSMIC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	Q9Y2X9	ZNF281	P49841	GSK3B	S785	K792R	792	Missense	distal	7	no	5.723	6.231	EPSD	COSMIC	6.007	Gain
CMGC_GSK_GSK3B_ST	Q9Y2X9	ZNF281	P49841	GSK3B	S837	G842V	842	Missense	distal	5	no	6.375	5.831	EPSD	COSMIC	6.007	Loss
CMGC_GSK_GSK3B_ST	Q9Y2X9	ZNF281	P49841	GSK3B	S837	S841L	841	Missense	distal	4	no	6.375	3.657	EPSD	COSMIC;GDSC	6.007	Loss
CMGC_GSK_GSK3B_ST	Q9Y2X9	ZNF281	P49841	GSK3B	S837	A834V	834	Missense	distal	-3	no	6.375	6.521	EPSD	COSMIC	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	P38936	CDKN1A	P49841	GSK3B	S27	L21F	21	Missense	distal	-6	no	8.454	8.402	EPSD	COSMIC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	P38936	CDKN1A	P49841	GSK3B	S27	R32C	32	Missense	distal	5	no	8.454	6.898	EPSD	COSMIC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	P38936	CDKN1A	P49841	GSK3B	S27	P24S	24	Missense	distal	-3	no	8.454	8.571	EPSD	COSMIC	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	P38936	CDKN1A	P49841	GSK3B	T57	D52V	52	Missense	distal	-5	no	5.880	6.187	EPSD;PhosphoSitePlus	COSMIC	6.007	Gain
CMGC_GSK_GSK3B_ST	P38936	CDKN1A	P49841	GSK3B	S98	T97I	97	Missense	proximal	-1	no	6.719	6.644	EPSD	COSMIC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	P38936	CDKN1A	P49841	GSK3B	S114	E108Q	108	Missense	distal	-6	no	6.439	6.496	PhosphoSitePlus;EPSD	COSMIC	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	P38936	CDKN1A	P49841	GSK3B	S114	S114L	114	Missense	central	0	yes	6.439	0.000	PhosphoSitePlus;EPSD	COSMIC	6.007	Loss
CMGC_GSK_GSK3B_ST	P38936	CDKN1A	P49841	GSK3B	S114	D112V	112	Missense	proximal	-2	no	6.439	6.422	PhosphoSitePlus;EPSD	COSMIC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	P38936	CDKN1A	P49841	GSK3B	S114	L113M	113	Missense	proximal	-1	no	6.439	6.463	PhosphoSitePlus;EPSD	COSMIC	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	P38936	CDKN1A	P49841	GSK3B	S114	D109H	109	Missense	distal	-5	no	6.439	6.333	PhosphoSitePlus;EPSD	COSMIC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	P38936	CDKN1A	P49841	GSK3B	S130	E125Q	125	Missense	distal	-5	no	7.588	7.300	EPSD	COSMIC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	P38936	CDKN1A	P49841	GSK3B	S130	S137T	137	Missense	distal	7	no	7.588	7.529	EPSD	COSMIC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	Q9BZS1	FOXP3	P49841	GSK3B	S19	S13F	13	Missense	distal	-6	no	9.591	9.538	EPSD	COSMIC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	Q9BZS1	FOXP3	P49841	GSK3B	S418	R420Q	420	Missense	proximal	2	no	7.903	8.107	EPSD	COSMIC	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	Q9BZS1	FOXP3	P49841	GSK3B	S418	R420W	420	Missense	proximal	2	no	7.903	7.473	EPSD	COSMIC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	Q9BZS1	FOXP3	P49841	GSK3B	S418	R414H	414	Missense	distal	-4	no	7.903	8.002	EPSD	COSMIC	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	Q9BZS1	FOXP3	P49841	GSK3B	S418	R417W	417	Missense	proximal	-1	no	7.903	8.014	EPSD	COSMIC;GDSC;CCLE	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	O43602	DCX	P49841	GSK3B	S28	R22W	22	Missense	distal	-6	no	9.996	10.024	EPSD	COSMIC	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	O43602	DCX	P49841	GSK3B	S28	P27T	27	Missense	proximal	-1	no	9.996	9.865	EPSD	COSMIC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	O43602	DCX	P49841	GSK3B	S28	S28I	28	Missense	central	0	yes	9.996	0.000	EPSD	COSMIC	6.007	Loss
CMGC_GSK_GSK3B_ST	O43602	DCX	P49841	GSK3B	S28	R22Q	22	Missense	distal	-6	no	9.996	10.049	EPSD	COSMIC	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	O43602	DCX	P49841	GSK3B	S28	A33T	33	Missense	distal	5	no	9.996	10.048	EPSD	COSMIC	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	O43602	DCX	P49841	GSK3B	S28	M23I	23	Missense	distal	-5	no	9.996	10.167	EPSD	COSMIC	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	O43602	DCX	P49841	GSK3B	S28	R22L	22	Missense	distal	-6	no	9.996	10.052	EPSD	COSMIC	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	O43602	DCX	P49841	GSK3B	S28	T30N	30	Missense	proximal	2	no	9.996	9.338	EPSD	COSMIC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	O43602	DCX	P49841	GSK3B	S28	H34Q	34	Missense	distal	6	no	9.996	10.002	EPSD	COSMIC	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	O43602	DCX	P49841	GSK3B	S28	S32C	32	Missense	distal	4	no	9.996	3.863	EPSD	COSMIC	6.007	Loss
CMGC_GSK_GSK3B_ST	O43602	DCX	P49841	GSK3B	S32	A33T	33	Missense	proximal	1	no	5.524	6.065	EPSD	COSMIC	6.007	Gain
CMGC_GSK_GSK3B_ST	O43602	DCX	P49841	GSK3B	S32	H34Q	34	Missense	proximal	2	no	5.524	6.071	EPSD	COSMIC	6.007	Gain
CMGC_GSK_GSK3B_ST	O43602	DCX	P49841	GSK3B	S161	S167N	167	Missense	distal	6	no	6.817	6.810	EPSD	COSMIC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	O43602	DCX	P49841	GSK3B	S161	S167G	167	Missense	distal	6	no	6.817	6.814	EPSD	COSMIC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	O43602	DCX	P49841	GSK3B	S161	S167C	167	Missense	distal	6	no	6.817	6.803	EPSD	COSMIC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	O43602	DCX	P49841	GSK3B	S161	S164R	164	Missense	distal	3	no	6.817	6.446	EPSD	COSMIC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	O43602	DCX	P49841	GSK3B	S161	Q160R	160	Missense	proximal	-1	no	6.817	6.786	EPSD	COSMIC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	O43602	DCX	P49841	GSK3B	S161	P159S	159	Missense	proximal	-2	no	6.817	6.560	EPSD	COSMIC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	O43602	DCX	P49841	GSK3B	S161	A158S	158	Missense	distal	-3	no	6.817	6.796	EPSD	COSMIC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	O43602	DCX	P49841	GSK3B	S161	Q160H	160	Missense	proximal	-1	no	6.817	6.872	EPSD	COSMIC	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	O43602	DCX	P49841	GSK3B	S161	K157E	157	Missense	distal	-4	no	6.817	7.084	EPSD	COSMIC	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	O43602	DCX	P49841	GSK3B	T289	S287F	287	Missense	proximal	-2	no	7.657	7.327	EPSD	COSMIC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	O43602	DCX	P49841	GSK3B	T289	P288L	288	Missense	proximal	-1	no	7.657	7.526	EPSD	COSMIC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	O43602	DCX	P49841	GSK3B	T289	P290L	290	Missense	proximal	1	no	7.657	4.797	EPSD	COSMIC	6.007	Loss
CMGC_GSK_GSK3B_ST	O43602	DCX	P49841	GSK3B	T289	P288A	288	Missense	proximal	-1	no	7.657	7.446	EPSD	COSMIC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	O43602	DCX	P49841	GSK3B	T289	P290H	290	Missense	proximal	1	no	7.657	3.957	EPSD	COSMIC	6.007	Loss
CMGC_GSK_GSK3B_ST	O43602	DCX	P49841	GSK3B	S297	S297N	297	Missense	central	0	yes	6.526	0.000	EPSD	COSMIC	6.007	Loss
CMGC_GSK_GSK3B_ST	O43602	DCX	P49841	GSK3B	S297	S297I	297	Missense	central	0	yes	6.526	0.000	EPSD	COSMIC	6.007	Loss
CMGC_GSK_GSK3B_ST	O43602	DCX	P49841	GSK3B	S297	P290L	290	Missense	distal	-7	no	6.526	6.528	EPSD	COSMIC	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	O43602	DCX	P49841	GSK3B	S297	P300S	300	Missense	distal	3	no	6.526	6.509	EPSD	COSMIC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	O43602	DCX	P49841	GSK3B	S297	G299V	299	Missense	proximal	2	no	6.526	6.515	EPSD	COSMIC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	O43602	DCX	P49841	GSK3B	S297	R302H	302	Missense	distal	5	no	6.526	5.537	EPSD	COSMIC	6.007	Loss
CMGC_GSK_GSK3B_ST	O43602	DCX	P49841	GSK3B	S297	R303Q	303	Missense	distal	6	no	6.526	6.527	EPSD	COSMIC	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	O43602	DCX	P49841	GSK3B	S297	P290H	290	Missense	distal	-7	no	6.526	6.546	EPSD	COSMIC	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	O43602	DCX	P49841	GSK3B	S306	S306F	306	Missense	central	0	yes	8.211	0.000	EPSD	COSMIC	6.007	Loss
CMGC_GSK_GSK3B_ST	O43602	DCX	P49841	GSK3B	S306	G311D	311	Missense	distal	5	no	8.211	8.275	EPSD	COSMIC	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	O43602	DCX	P49841	GSK3B	S306	D313N	313	Missense	distal	7	no	8.211	8.279	EPSD	COSMIC	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	O43602	DCX	P49841	GSK3B	S306	P300S	300	Missense	distal	-6	no	8.211	8.190	EPSD	COSMIC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	O43602	DCX	P49841	GSK3B	S306	G299V	299	Missense	distal	-7	no	8.211	8.234	EPSD	COSMIC	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	O43602	DCX	P49841	GSK3B	S306	N312D	312	Missense	distal	6	no	8.211	8.210	EPSD	COSMIC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	O43602	DCX	P49841	GSK3B	S306	R302H	302	Missense	distal	-4	no	8.211	8.310	EPSD	COSMIC	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	O43602	DCX	P49841	GSK3B	S306	G311S	311	Missense	distal	5	no	8.211	8.168	EPSD	COSMIC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	O43602	DCX	P49841	GSK3B	S306	N312K	312	Missense	distal	6	no	8.211	8.212	EPSD	COSMIC	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	O43602	DCX	P49841	GSK3B	S306	G311V	311	Missense	distal	5	no	8.211	7.667	EPSD	COSMIC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	O43602	DCX	P49841	GSK3B	S306	G311C	311	Missense	distal	5	no	8.211	6.929	EPSD	COSMIC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	O43602	DCX	P49841	GSK3B	S306	D313G	313	Missense	distal	7	no	8.211	8.176	EPSD	COSMIC;CCLE	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	O43602	DCX	P49841	GSK3B	S306	R303Q	303	Missense	distal	-3	no	8.211	8.072	EPSD	COSMIC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	O43602	DCX	P49841	GSK3B	S321	P327S	327	Missense	distal	6	no	6.656	6.654	EPSD	COSMIC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	O43602	DCX	P49841	GSK3B	S321	S320Y	320	Missense	proximal	-1	no	6.656	6.516	EPSD	COSMIC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	O43602	DCX	P49841	GSK3B	S321	N317D	317	Missense	distal	-4	no	6.656	7.353	EPSD	COSMIC	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	O43602	DCX	P49841	GSK3B	S321	S320A	320	Missense	proximal	-1	no	6.656	6.501	EPSD	COSMIC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	O43602	DCX	P49841	GSK3B	S321	S320F	320	Missense	proximal	-1	no	6.656	6.525	EPSD	COSMIC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	O43602	DCX	P49841	GSK3B	S321	P327R	327	Missense	distal	6	no	6.656	6.649	EPSD	COSMIC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	O43602	DCX	P49841	GSK3B	S322	P327S	327	Missense	distal	5	no	7.560	6.606	EPSD	COSMIC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	O43602	DCX	P49841	GSK3B	S322	S320Y	320	Missense	proximal	-2	no	7.560	7.241	EPSD	COSMIC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	O43602	DCX	P49841	GSK3B	S322	N317D	317	Missense	distal	-5	no	7.560	8.124	EPSD	COSMIC	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	O43602	DCX	P49841	GSK3B	S322	S329F	329	Missense	distal	7	no	7.560	7.637	EPSD	COSMIC	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	O43602	DCX	P49841	GSK3B	S322	S320A	320	Missense	proximal	-2	no	7.560	7.225	EPSD	COSMIC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	O43602	DCX	P49841	GSK3B	S322	S320F	320	Missense	proximal	-2	no	7.560	7.229	EPSD	COSMIC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	O43602	DCX	P49841	GSK3B	S322	P327R	327	Missense	distal	5	no	7.560	6.922	EPSD	COSMIC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	O43602	DCX	P49841	GSK3B	S325	P327S	327	Missense	proximal	2	no	7.174	6.730	EPSD	COSMIC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	O43602	DCX	P49841	GSK3B	S325	S320Y	320	Missense	distal	-5	no	7.174	7.826	EPSD	COSMIC	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	O43602	DCX	P49841	GSK3B	S325	S329F	329	Missense	distal	4	no	7.174	3.559	EPSD	COSMIC	6.007	Loss
CMGC_GSK_GSK3B_ST	O43602	DCX	P49841	GSK3B	S325	S320A	320	Missense	distal	-5	no	7.174	7.451	EPSD	COSMIC	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	O43602	DCX	P49841	GSK3B	S325	Q331H	331	Missense	distal	6	no	7.174	7.167	EPSD	COSMIC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	O43602	DCX	P49841	GSK3B	S325	S320F	320	Missense	distal	-5	no	7.174	7.733	EPSD	COSMIC	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	O43602	DCX	P49841	GSK3B	S325	P327R	327	Missense	proximal	2	no	7.174	6.748	EPSD	COSMIC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	O43602	DCX	P49841	GSK3B	S332	P327S	327	Missense	distal	-5	no	10.481	10.638	EPSD	COSMIC	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	O43602	DCX	P49841	GSK3B	S332	S329F	329	Missense	distal	-3	no	10.481	10.548	EPSD	COSMIC	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	O43602	DCX	P49841	GSK3B	S332	T336M	336	Missense	distal	4	no	10.481	9.115	EPSD	COSMIC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	O43602	DCX	P49841	GSK3B	S332	T338N	338	Missense	distal	6	no	10.481	10.473	EPSD	COSMIC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	O43602	DCX	P49841	GSK3B	S332	Q331H	331	Missense	proximal	-1	no	10.481	10.536	EPSD	COSMIC	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	O43602	DCX	P49841	GSK3B	S332	P327R	327	Missense	distal	-5	no	10.481	11.335	EPSD	COSMIC	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	O43602	DCX	P49841	GSK3B	S335	P340S	340	Missense	distal	5	no	7.631	6.677	EPSD	COSMIC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	O43602	DCX	P49841	GSK3B	S335	G341D	341	Missense	distal	6	no	7.631	7.627	EPSD	COSMIC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	O43602	DCX	P49841	GSK3B	S335	S329F	329	Missense	distal	-6	no	7.631	7.578	EPSD	COSMIC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	O43602	DCX	P49841	GSK3B	S335	P340T	340	Missense	distal	5	no	7.631	6.654	EPSD	COSMIC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	O43602	DCX	P49841	GSK3B	S335	T336M	336	Missense	proximal	1	no	7.631	7.235	EPSD	COSMIC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	O43602	DCX	P49841	GSK3B	S335	T338N	338	Missense	distal	3	no	7.631	7.712	EPSD	COSMIC	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	O43602	DCX	P49841	GSK3B	S335	Q331H	331	Missense	distal	-4	no	7.631	7.373	EPSD	COSMIC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	O43602	DCX	P49841	GSK3B	T336	P340S	340	Missense	distal	4	no	7.685	10.656	EPSD	COSMIC	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	O43602	DCX	P49841	GSK3B	T336	G341D	341	Missense	distal	5	no	7.685	7.748	EPSD	COSMIC	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	O43602	DCX	P49841	GSK3B	T336	S329F	329	Missense	distal	-7	no	7.685	7.695	EPSD	COSMIC	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	O43602	DCX	P49841	GSK3B	T336	P340T	340	Missense	distal	4	no	7.685	9.787	EPSD	COSMIC	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	O43602	DCX	P49841	GSK3B	T336	T336M	336	Missense	central	0	yes	7.685	0.000	EPSD	COSMIC	6.007	Loss
CMGC_GSK_GSK3B_ST	O43602	DCX	P49841	GSK3B	T336	T338N	338	Missense	proximal	2	no	7.685	7.027	EPSD	COSMIC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	O43602	DCX	P49841	GSK3B	T336	Q331H	331	Missense	distal	-5	no	7.685	7.709	EPSD	COSMIC	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	O43602	DCX	P49841	GSK3B	S339	P340S	340	Missense	proximal	1	no	8.725	4.880	EPSD	COSMIC	6.007	Loss
CMGC_GSK_GSK3B_ST	O43602	DCX	P49841	GSK3B	S339	G341D	341	Missense	proximal	2	no	8.725	9.075	EPSD	COSMIC	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	O43602	DCX	P49841	GSK3B	S339	P340T	340	Missense	proximal	1	no	8.725	5.534	EPSD	COSMIC	6.007	Loss
CMGC_GSK_GSK3B_ST	O43602	DCX	P49841	GSK3B	S339	T336M	336	Missense	distal	-3	no	8.725	8.672	EPSD	COSMIC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	O43602	DCX	P49841	GSK3B	S339	T338N	338	Missense	proximal	-1	no	8.725	8.862	EPSD	COSMIC	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	O43602	DCX	P49841	GSK3B	S339	R344W	344	Missense	distal	5	no	8.725	7.423	EPSD	COSMIC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	O43602	DCX	P49841	GSK3B	S339	H346N	346	Missense	distal	7	no	8.725	8.222	EPSD	COSMIC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	O43602	DCX	P49841	GSK3B	S354	K347N	347	Missense	distal	-7	no	7.661	7.646	EPSD	COSMIC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	O43602	DCX	P49841	GSK3B	S354	D356N	356	Missense	proximal	2	no	7.661	7.038	EPSD	COSMIC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	O43602	DCX	P49841	GSK3B	S354	L353M	353	Missense	proximal	-1	no	7.661	7.686	EPSD	COSMIC	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	O43602	DCX	P49841	GSK3B	S354	D348A	348	Missense	distal	-6	no	7.661	7.697	EPSD	COSMIC	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	O43602	DCX	P49841	GSK3B	S354	D348N	348	Missense	distal	-6	no	7.661	7.684	EPSD	COSMIC	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	O43602	DCX	P49841	GSK3B	S354	L349M	349	Missense	distal	-5	no	7.661	7.854	EPSD	COSMIC	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	O43602	DCX	P49841	GSK3B	S354	D359N	359	Missense	distal	5	no	7.661	7.235	EPSD	COSMIC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	O43602	DCX	P49841	GSK3B	S354	D357N	357	Missense	distal	3	no	7.661	7.615	EPSD	COSMIC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	O43602	DCX	P49841	GSK3B	S360	D356N	356	Missense	distal	-4	no	7.926	7.229	EPSD	COSMIC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	O43602	DCX	P49841	GSK3B	S360	L353M	353	Missense	distal	-7	no	7.926	7.947	EPSD	COSMIC	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	O43602	DCX	P49841	GSK3B	S360	D363N	363	Missense	distal	3	no	7.926	7.880	EPSD	COSMIC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	O43602	DCX	P49841	GSK3B	S360	D359N	359	Missense	proximal	-1	no	7.926	8.048	EPSD	COSMIC	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	O43602	DCX	P49841	GSK3B	S360	D357N	357	Missense	distal	-3	no	7.926	7.785	EPSD	COSMIC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	P22670	RFX1	P49841	GSK3B	S120	G122C	122	Missense	proximal	2	no	10.017	9.783	EPSD;PhosphoSitePlus	COSMIC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	P22670	RFX1	P49841	GSK3B	T124	G122C	122	Missense	proximal	-2	no	6.700	6.506	PhosphoSitePlus;EPSD	COSMIC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	P22670	RFX1	P49841	GSK3B	S453	Y460C	460	Missense	distal	7	no	7.332	7.282	EPSD	COSMIC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	P22670	RFX1	P49841	GSK3B	S949	A951T	951	Missense	proximal	2	no	6.024	6.142	EPSD	COSMIC;CCLE	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	P08238	HSP90AB1	P49841	GSK3B	S470	T467I	467	Missense	distal	-3	no	7.219	7.307	EPSD	COSMIC	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	P08238	HSP90AB1	P49841	GSK3B	S470	E471Q	471	Missense	proximal	1	no	7.219	7.784	EPSD	COSMIC	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	P08238	HSP90AB1	P49841	GSK3B	S470	Y472C	472	Missense	proximal	2	no	7.219	6.958	EPSD	COSMIC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	P08238	HSP90AB1	P49841	GSK3B	S470	Y472H	472	Missense	proximal	2	no	7.219	7.126	EPSD	COSMIC;GDSC;CCLE	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	P08238	HSP90AB1	P49841	GSK3B	S470	V473A	473	Missense	distal	3	no	7.219	7.090	EPSD	COSMIC;GDSC;CCLE	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	P08238	HSP90AB1	P49841	GSK3B	S669	G667D	667	Missense	proximal	-2	no	6.872	6.974	EPSD	COSMIC	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	P08238	HSP90AB1	P49841	GSK3B	S669	D672G	672	Missense	distal	3	no	6.872	6.821	EPSD	COSMIC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	P08238	HSP90AB1	P49841	GSK3B	S718	A717V	717	Missense	proximal	-1	no	5.809	6.012	PhosphoSitePlus	COSMIC;GDSC;CCLE	6.007	Gain
CMGC_GSK_GSK3B_ST	Q15797	SMAD1	P49841	GSK3B	S11	K15R	15	Missense	distal	4	no	6.040	6.204	EPSD	COSMIC	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	Q15797	SMAD1	P49841	GSK3B	S11	K15N	15	Missense	distal	4	no	6.040	5.632	EPSD	COSMIC	6.007	Loss
CMGC_GSK_GSK3B_ST	Q15797	SMAD1	P49841	GSK3B	S132	V130L	130	Missense	proximal	-2	no	7.361	7.320	EPSD	COSMIC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	Q15797	SMAD1	P49841	GSK3B	S132	Y127C	127	Missense	distal	-5	no	7.361	7.228	EPSD	COSMIC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	Q15797	SMAD1	P49841	GSK3B	S187	P188S	188	Missense	proximal	1	no	9.456	5.611	EPSD	COSMIC	6.007	Loss
CMGC_GSK_GSK3B_ST	Q15797	SMAD1	P49841	GSK3B	S187	P183L	183	Missense	distal	-4	no	9.456	8.669	EPSD	COSMIC;CCLE	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	Q15797	SMAD1	P49841	GSK3B	S195	P188S	188	Missense	distal	-7	no	11.405	11.406	EPSD	COSMIC	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	Q15797	SMAD1	P49841	GSK3B	T202	H205Y	205	Missense	distal	3	no	9.463	9.070	PhosphoSitePlus	COSMIC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	Q15797	SMAD1	P49841	GSK3B	T202	H205N	205	Missense	distal	3	no	9.463	9.540	PhosphoSitePlus	COSMIC	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	Q15797	SMAD1	P49841	GSK3B	S206	H205Y	205	Missense	proximal	-1	no	10.197	10.108	EPSD	COSMIC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	Q15797	SMAD1	P49841	GSK3B	S206	H205N	205	Missense	proximal	-1	no	10.197	10.310	EPSD	COSMIC	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	Q15797	SMAD1	P49841	GSK3B	T452	Q445L	445	Missense	distal	-7	no	6.307	6.292	EPSD	COSMIC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	Q15853	USF2	P49841	GSK3B	S151	I146T	146	Missense	distal	-5	no	6.172	5.989	EPSD	COSMIC	6.007	Loss
CMGC_GSK_GSK3B_ST	Q15853	USF2	P49841	GSK3B	S151	S151N	151	Missense	central	0	yes	6.172	0.000	EPSD	COSMIC	6.007	Loss
CMGC_GSK_GSK3B_ST	Q15853	USF2	P49841	GSK3B	S151	P156L	156	Missense	distal	5	no	6.172	4.892	EPSD	COSMIC	6.007	Loss
CMGC_GSK_GSK3B_ST	Q15853	USF2	P49841	GSK3B	S151	P149L	149	Missense	proximal	-2	no	6.172	5.842	EPSD	COSMIC	6.007	Loss
CMGC_GSK_GSK3B_ST	Q15853	USF2	P49841	GSK3B	S151	S155N	155	Missense	distal	4	no	6.172	2.562	EPSD	COSMIC	6.007	Loss
CMGC_GSK_GSK3B_ST	Q15853	USF2	P49841	GSK3B	S155	S151N	151	Missense	distal	-4	no	9.261	7.964	EPSD;PhosphoSitePlus	COSMIC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	Q15853	USF2	P49841	GSK3B	S155	P156L	156	Missense	proximal	1	no	9.261	6.401	EPSD;PhosphoSitePlus	COSMIC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	Q15853	USF2	P49841	GSK3B	S155	P149L	149	Missense	distal	-6	no	9.261	9.239	EPSD;PhosphoSitePlus	COSMIC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	Q15853	USF2	P49841	GSK3B	S155	S155N	155	Missense	central	0	yes	9.261	0.000	EPSD;PhosphoSitePlus	COSMIC	6.007	Loss
CMGC_GSK_GSK3B_ST	Q15853	USF2	P49841	GSK3B	S222	R229C	229	Missense	distal	7	no	8.345	8.299	EPSD	COSMIC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	Q15853	USF2	P49841	GSK3B	T230	R229C	229	Missense	proximal	-1	no	8.881	8.982	PhosphoSitePlus;EPSD	COSMIC	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	Q07820	MCL1	P49841	GSK3B	S60	G58S	58	Missense	proximal	-2	no	6.160	6.278	EPSD	COSMIC	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	Q07820	MCL1	P49841	GSK3B	S60	A55S	55	Missense	distal	-5	no	6.160	5.883	EPSD	COSMIC	6.007	Loss
CMGC_GSK_GSK3B_ST	Q07820	MCL1	P49841	GSK3B	S60	G59E	59	Missense	proximal	-1	no	6.160	6.142	EPSD	COSMIC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	Q07820	MCL1	P49841	GSK3B	S60	P65L	65	Missense	distal	5	no	6.160	4.879	EPSD	COSMIC	6.007	Loss
CMGC_GSK_GSK3B_ST	Q07820	MCL1	P49841	GSK3B	S64	G58S	58	Missense	distal	-6	no	10.611	10.595	EPSD	COSMIC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	Q07820	MCL1	P49841	GSK3B	S64	G59E	59	Missense	distal	-5	no	10.611	10.576	EPSD	COSMIC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	Q07820	MCL1	P49841	GSK3B	S64	P65L	65	Missense	proximal	1	no	10.611	7.750	EPSD	COSMIC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	Q07820	MCL1	P49841	GSK3B	T70	D72G	72	Missense	proximal	2	no	6.124	5.774	EPSD	COSMIC	6.007	Loss
CMGC_GSK_GSK3B_ST	Q07820	MCL1	P49841	GSK3B	T70	P65L	65	Missense	distal	-5	no	6.124	6.389	EPSD	COSMIC	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	Q07820	MCL1	P49841	GSK3B	T70	A77V	77	Missense	distal	7	no	6.124	6.202	EPSD	COSMIC	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	Q07820	MCL1	P49841	GSK3B	S121	L126M	126	Missense	distal	5	no	7.881	8.068	EPSD;PhosphoSitePlus	COSMIC	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	Q07820	MCL1	P49841	GSK3B	S121	A116P	116	Missense	distal	-5	no	7.881	7.447	EPSD;PhosphoSitePlus	COSMIC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	Q07820	MCL1	P49841	GSK3B	S121	P122L	122	Missense	proximal	1	no	7.881	5.020	EPSD;PhosphoSitePlus	COSMIC	6.007	Loss
CMGC_GSK_GSK3B_ST	Q07820	MCL1	P49841	GSK3B	S150	G151H	151	Missense	proximal	1	no	6.613	6.107	EPSD	COSMIC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	Q07820	MCL1	P49841	GSK3B	S150	N152S	152	Missense	proximal	2	no	6.613	7.145	EPSD	COSMIC	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	Q07820	MCL1	P49841	GSK3B	S150	G148R	148	Missense	proximal	-2	no	6.613	6.615	EPSD	COSMIC	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	Q07820	MCL1	P49841	GSK3B	S150	E145Q	145	Missense	distal	-5	no	6.613	6.325	EPSD	COSMIC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	Q07820	MCL1	P49841	GSK3B	S150	N153D	153	Missense	distal	3	no	6.613	6.660	EPSD	COSMIC	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	Q07820	MCL1	P49841	GSK3B	S150	S150A	150	Missense	central	0	yes	6.613	0.000	EPSD	COSMIC	6.007	Loss
CMGC_GSK_GSK3B_ST	Q07820	MCL1	P49841	GSK3B	S150	S155G	155	Missense	distal	5	no	6.613	6.655	EPSD	COSMIC	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	Q07820	MCL1	P49841	GSK3B	S155	G151H	151	Missense	distal	-4	no	6.717	6.058	EPSD	COSMIC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	Q07820	MCL1	P49841	GSK3B	S155	N152S	152	Missense	distal	-3	no	6.717	6.812	EPSD	COSMIC	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	Q07820	MCL1	P49841	GSK3B	S155	P161F	161	Missense	distal	6	no	6.717	6.703	EPSD	COSMIC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	Q07820	MCL1	P49841	GSK3B	S155	G148R	148	Missense	distal	-7	no	6.717	6.738	EPSD	COSMIC	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	Q07820	MCL1	P49841	GSK3B	S155	P161H	161	Missense	distal	6	no	6.717	6.706	EPSD	COSMIC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	Q07820	MCL1	P49841	GSK3B	S155	G158R	158	Missense	distal	3	no	6.717	6.303	EPSD	COSMIC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	Q07820	MCL1	P49841	GSK3B	S155	N153D	153	Missense	proximal	-2	no	6.717	6.930	EPSD	COSMIC	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	Q07820	MCL1	P49841	GSK3B	S155	S150A	150	Missense	distal	-5	no	6.717	6.995	EPSD	COSMIC	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	Q07820	MCL1	P49841	GSK3B	S155	S155G	155	Missense	central	0	yes	6.717	0.000	EPSD	COSMIC	6.007	Loss
CMGC_GSK_GSK3B_ST	Q07820	MCL1	P49841	GSK3B	S155	G158D	158	Missense	distal	3	no	6.717	6.768	EPSD	COSMIC	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	Q07820	MCL1	P49841	GSK3B	S159	N152S	152	Missense	distal	-7	no	9.113	9.107	PhosphoSitePlus;EPSD	COSMIC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	Q07820	MCL1	P49841	GSK3B	S159	P161F	161	Missense	proximal	2	no	9.113	8.324	PhosphoSitePlus;EPSD	COSMIC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	Q07820	MCL1	P49841	GSK3B	S159	P161H	161	Missense	proximal	2	no	9.113	8.344	PhosphoSitePlus;EPSD	COSMIC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	Q07820	MCL1	P49841	GSK3B	S159	G158R	158	Missense	proximal	-1	no	9.113	8.969	PhosphoSitePlus;EPSD	COSMIC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	Q07820	MCL1	P49841	GSK3B	S159	N153D	153	Missense	distal	-6	no	9.113	9.090	PhosphoSitePlus;EPSD	COSMIC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	Q07820	MCL1	P49841	GSK3B	S159	S155G	155	Missense	distal	-4	no	9.113	8.685	PhosphoSitePlus;EPSD	COSMIC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	Q07820	MCL1	P49841	GSK3B	S159	G158D	158	Missense	proximal	-1	no	9.113	9.046	PhosphoSitePlus;EPSD	COSMIC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	Q07820	MCL1	P49841	GSK3B	T163	P161F	161	Missense	proximal	-2	no	9.133	8.546	EPSD;PhosphoSitePlus	COSMIC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	Q07820	MCL1	P49841	GSK3B	T163	P161H	161	Missense	proximal	-2	no	9.133	8.771	EPSD;PhosphoSitePlus	COSMIC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	Q07820	MCL1	P49841	GSK3B	T163	G158R	158	Missense	distal	-5	no	9.133	9.364	EPSD;PhosphoSitePlus	COSMIC	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	Q07820	MCL1	P49841	GSK3B	T163	G158D	158	Missense	distal	-5	no	9.133	8.939	EPSD;PhosphoSitePlus	COSMIC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	Q07820	MCL1	P49841	GSK3B	S202	K197M	197	Missense	distal	-5	no	8.126	8.227	EPSD	COSMIC	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	Q07820	MCL1	P49841	GSK3B	S206	T212A	212	Missense	distal	6	no	7.022	7.018	EPSD	COSMIC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	P24864	CCNE1	P49841	GSK3B	S73	P71S	71	Missense	proximal	-2	no	9.837	9.580	PhosphoSitePlus;EPSD	COSMIC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	P24864	CCNE1	P49841	GSK3B	S73	A69T	69	Missense	distal	-4	no	9.837	10.661	PhosphoSitePlus;EPSD	COSMIC	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	P24864	CCNE1	P49841	GSK3B	S73	A69V	69	Missense	distal	-4	no	9.837	9.763	PhosphoSitePlus;EPSD	COSMIC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	P24864	CCNE1	P49841	GSK3B	S73	C68F	68	Missense	distal	-5	no	9.837	9.877	PhosphoSitePlus;EPSD	COSMIC;GDSC;CCLE	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	P24864	CCNE1	P49841	GSK3B	S73	P76L	76	Missense	distal	3	no	9.837	9.518	PhosphoSitePlus;EPSD	COSMIC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	P24864	CCNE1	P49841	GSK3B	S73	A69S	69	Missense	distal	-4	no	9.837	10.996	PhosphoSitePlus;EPSD	COSMIC;CCLE	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	P24864	CCNE1	P49841	GSK3B	T77	D79N	79	Missense	proximal	2	no	8.454	7.830	EPSD;PhosphoSitePlus	COSMIC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	P24864	CCNE1	P49841	GSK3B	T77	P71S	71	Missense	distal	-6	no	8.454	8.433	EPSD;PhosphoSitePlus	COSMIC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	P24864	CCNE1	P49841	GSK3B	T77	P76L	76	Missense	proximal	-1	no	8.454	8.322	EPSD;PhosphoSitePlus	COSMIC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	P24864	CCNE1	P49841	GSK3B	S103	V107L	107	Missense	distal	4	no	7.875	7.548	EPSD	COSMIC;CCLE	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	P24864	CCNE1	P49841	GSK3B	S387	L389F	389	Missense	proximal	2	no	10.298	9.894	EPSD	COSMIC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	P24864	CCNE1	P49841	GSK3B	S387	S381C	381	Missense	distal	-6	no	10.298	10.287	EPSD	COSMIC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	P24864	CCNE1	P49841	GSK3B	S387	S391R	391	Missense	distal	4	no	10.298	7.260	EPSD	COSMIC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	P24864	CCNE1	P49841	GSK3B	S387	A386V	386	Missense	proximal	-1	no	10.298	10.501	EPSD	COSMIC	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	P24864	CCNE1	P49841	GSK3B	S387	N384K	384	Missense	distal	-3	no	10.298	10.417	EPSD	COSMIC;GDSC;CCLE	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	P24864	CCNE1	P49841	GSK3B	S391	L389F	389	Missense	proximal	-2	no	6.714	6.458	EPSD	COSMIC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	P24864	CCNE1	P49841	GSK3B	S391	S391R	391	Missense	central	0	yes	6.714	0.000	EPSD	COSMIC	6.007	Loss
CMGC_GSK_GSK3B_ST	P24864	CCNE1	P49841	GSK3B	S391	T395P	395	Missense	distal	4	no	6.714	4.612	EPSD	COSMIC	6.007	Loss
CMGC_GSK_GSK3B_ST	P24864	CCNE1	P49841	GSK3B	S391	A386V	386	Missense	distal	-5	no	6.714	7.017	EPSD	COSMIC	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	P24864	CCNE1	P49841	GSK3B	S391	N384K	384	Missense	distal	-7	no	6.714	6.730	EPSD	COSMIC;GDSC;CCLE	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	P24864	CCNE1	P49841	GSK3B	T395	L389F	389	Missense	distal	-6	no	9.736	9.684	EPSD;PhosphoSitePlus	COSMIC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	P24864	CCNE1	P49841	GSK3B	T395	S391R	391	Missense	distal	-4	no	9.736	8.549	EPSD;PhosphoSitePlus	COSMIC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	P24864	CCNE1	P49841	GSK3B	T395	T395P	395	Missense	central	0	yes	9.736	0.000	EPSD;PhosphoSitePlus	COSMIC	6.007	Loss
CMGC_GSK_GSK3B_ST	Q9Y6K9	IKBKG	P49841	GSK3B	S31	V26I	26	Missense	distal	-5	no	9.414	9.307	PhosphoSitePlus;EPSD	COSMIC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	Q9BPU6	DPYSL5	P49841	GSK3B	T490	R489H	489	Missense	proximal	-1	no	6.275	6.361	EPSD	COSMIC	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	Q9BPU6	DPYSL5	P49841	GSK3B	T490	P491F	491	Missense	proximal	1	no	6.275	2.044	EPSD	COSMIC	6.007	Loss
CMGC_GSK_GSK3B_ST	Q9BPU6	DPYSL5	P49841	GSK3B	T490	D495N	495	Missense	distal	5	no	6.275	5.848	EPSD	COSMIC	6.007	Loss
CMGC_GSK_GSK3B_ST	Q9BPU6	DPYSL5	P49841	GSK3B	T509	P515S	515	Missense	distal	6	no	6.077	6.075	EPSD	COSMIC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	Q9BPU6	DPYSL5	P49841	GSK3B	T516	T520P	520	Missense	distal	4	no	6.248	4.146	PhosphoSitePlus	COSMIC	6.007	Loss
CMGC_GSK_GSK3B_ST	Q9BPU6	DPYSL5	P49841	GSK3B	T516	P515S	515	Missense	proximal	-1	no	6.248	6.192	PhosphoSitePlus	COSMIC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	Q9BPU6	DPYSL5	P49841	GSK3B	S534	H529Y	529	Missense	distal	-5	no	7.805	8.290	EPSD	COSMIC	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	Q9BPU6	DPYSL5	P49841	GSK3B	S534	H529D	529	Missense	distal	-5	no	7.805	7.911	EPSD	COSMIC	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	Q96F46	IL17RA	P49841	GSK3B	S561	R560Q	560	Missense	proximal	-1	no	6.951	6.981	EPSD	COSMIC	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	Q96F46	IL17RA	P49841	GSK3B	S561	L567M	567	Missense	distal	6	no	6.951	6.950	EPSD	COSMIC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	Q96F46	IL17RA	P49841	GSK3B	S708	E701K	701	Missense	distal	-7	no	6.692	6.681	EPSD	COSMIC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	Q96F46	IL17RA	P49841	GSK3B	S708	L706F	706	Missense	proximal	-2	no	6.692	6.436	EPSD	COSMIC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	Q96F46	IL17RA	P49841	GSK3B	S708	L705I	705	Missense	distal	-3	no	6.692	6.796	EPSD	COSMIC	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	Q96F46	IL17RA	P49841	GSK3B	S726	P733L	733	Missense	distal	7	no	10.550	10.599	EPSD	COSMIC	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	Q96F46	IL17RA	P49841	GSK3B	T732	P733L	733	Missense	proximal	1	no	7.850	4.989	EPSD	COSMIC	6.007	Loss
CMGC_GSK_GSK3B_ST	Q96F46	IL17RA	P49841	GSK3B	T732	L739I	739	Missense	distal	7	no	7.850	8.199	EPSD	COSMIC	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	Q96F46	IL17RA	P49841	GSK3B	S736	P733L	733	Missense	distal	-3	no	6.973	7.099	EPSD	COSMIC	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	Q96F46	IL17RA	P49841	GSK3B	S736	L740F	740	Missense	distal	4	no	6.973	6.077	EPSD	COSMIC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	Q96F46	IL17RA	P49841	GSK3B	S736	L739I	739	Missense	distal	3	no	6.973	6.853	EPSD	COSMIC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	Q96F46	IL17RA	P49841	GSK3B	T780	E784A	784	Missense	distal	4	no	9.209	8.818	PhosphoSitePlus	COSMIC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	Q96F46	IL17RA	P49841	GSK3B	S798	P802S	802	Missense	distal	4	no	4.733	7.704	EPSD	COSMIC;GDSC;CCLE	6.007	Gain
CMGC_GSK_GSK3B_ST	Q96F46	IL17RA	P49841	GSK3B	S801	S800C	800	Missense	proximal	-1	no	7.580	7.544	EPSD	COSMIC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	Q96F46	IL17RA	P49841	GSK3B	S801	P802S	802	Missense	proximal	1	no	7.580	3.736	EPSD	COSMIC;GDSC;CCLE	6.007	Loss
CMGC_GSK_GSK3B_ST	Q96F46	IL17RA	P49841	GSK3B	S829	A825V	825	Missense	distal	-4	no	7.197	7.123	EPSD	COSMIC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	Q13485	SMAD4	P49841	GSK3B	T9	A15V	15	Missense	distal	6	no	6.597	6.589	EPSD	COSMIC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	Q13485	SMAD4	P49841	GSK3B	T9	A15T	15	Missense	distal	6	no	6.597	6.601	EPSD	COSMIC	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	Q13485	SMAD4	P49841	GSK3B	T9	I6V	6	Missense	distal	-3	no	6.597	6.651	EPSD	COSMIC	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	Q13485	SMAD4	P49841	GSK3B	T9	N3D	3	Missense	distal	-6	no	6.597	6.574	EPSD	COSMIC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	Q13485	SMAD4	P49841	GSK3B	S42	K46T	46	Missense	distal	4	no	4.083	6.417	EPSD	COSMIC	6.007	Gain
CMGC_GSK_GSK3B_ST	Q13485	SMAD4	P49841	GSK3B	S138	L143F	143	Missense	distal	5	no	6.678	6.337	EPSD	COSMIC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	Q13485	SMAD4	P49841	GSK3B	S138	E134D	134	Missense	distal	-4	no	6.678	6.674	EPSD	COSMIC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	Q13485	SMAD4	P49841	GSK3B	S138	R135Q	135	Missense	distal	-3	no	6.678	6.539	EPSD	COSMIC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	Q13485	SMAD4	P49841	GSK3B	S138	Y133H	133	Missense	distal	-5	no	6.678	6.192	EPSD	COSMIC;GDSC;CCLE	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	Q13485	SMAD4	P49841	GSK3B	S138	G140E	140	Missense	proximal	2	no	6.678	6.849	EPSD	COSMIC	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	Q13485	SMAD4	P49841	GSK3B	S138	H132L	132	Missense	distal	-6	no	6.678	6.710	EPSD	COSMIC	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	Q13485	SMAD4	P49841	GSK3B	S138	L143H	143	Missense	distal	5	no	6.678	6.331	EPSD	COSMIC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	Q13485	SMAD4	P49841	GSK3B	S138	S138L	138	Missense	central	0	yes	6.678	0.000	EPSD	COSMIC	6.007	Loss
CMGC_GSK_GSK3B_ST	Q13485	SMAD4	P49841	GSK3B	S138	H132N	132	Missense	distal	-6	no	6.678	6.709	EPSD	COSMIC	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	Q13485	SMAD4	P49841	GSK3B	T265	H262R	262	Missense	distal	-3	no	7.440	7.497	EPSD;PhosphoSitePlus	COSMIC	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	Q13485	SMAD4	P49841	GSK3B	T265	N263S	263	Missense	proximal	-2	no	7.440	7.669	EPSD;PhosphoSitePlus	COSMIC	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	Q13485	SMAD4	P49841	GSK3B	T265	W268L	268	Missense	distal	3	no	7.440	7.252	EPSD;PhosphoSitePlus	COSMIC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	Q13485	SMAD4	P49841	GSK3B	T265	W268C	268	Missense	distal	3	no	7.440	7.337	EPSD;PhosphoSitePlus	COSMIC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	Q13485	SMAD4	P49841	GSK3B	T265	H262L	262	Missense	distal	-3	no	7.440	7.338	EPSD;PhosphoSitePlus	COSMIC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	Q13485	SMAD4	P49841	GSK3B	T265	R272S	272	Missense	distal	7	no	7.440	7.003	EPSD;PhosphoSitePlus	COSMIC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	Q13485	SMAD4	P49841	GSK3B	T265	T265I	265	Missense	central	0	yes	7.440	0.000	EPSD;PhosphoSitePlus	COSMIC	6.007	Loss
CMGC_GSK_GSK3B_ST	Q13485	SMAD4	P49841	GSK3B	T269	A274E	274	Missense	distal	5	no	6.109	6.492	EPSD;PhosphoSitePlus	COSMIC	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	Q13485	SMAD4	P49841	GSK3B	T269	P275S	275	Missense	distal	6	no	6.109	6.107	EPSD;PhosphoSitePlus	COSMIC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	Q13485	SMAD4	P49841	GSK3B	T269	N263S	263	Missense	distal	-6	no	6.109	6.111	EPSD;PhosphoSitePlus	COSMIC	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	Q13485	SMAD4	P49841	GSK3B	T269	W268L	268	Missense	proximal	-1	no	6.109	6.059	EPSD;PhosphoSitePlus	COSMIC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	Q13485	SMAD4	P49841	GSK3B	T269	W268C	268	Missense	proximal	-1	no	6.109	6.098	EPSD;PhosphoSitePlus	COSMIC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	Q13485	SMAD4	P49841	GSK3B	T269	H262L	262	Missense	distal	-7	no	6.109	6.091	EPSD;PhosphoSitePlus	COSMIC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	Q13485	SMAD4	P49841	GSK3B	T269	P275L	275	Missense	distal	6	no	6.109	6.102	EPSD;PhosphoSitePlus	COSMIC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	Q13485	SMAD4	P49841	GSK3B	T269	R272S	272	Missense	distal	3	no	6.109	6.480	EPSD;PhosphoSitePlus	COSMIC	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	Q13485	SMAD4	P49841	GSK3B	T269	T273S	273	Missense	distal	4	no	6.109	6.978	EPSD;PhosphoSitePlus	COSMIC	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	Q13485	SMAD4	P49841	GSK3B	T269	T265I	265	Missense	distal	-4	no	6.109	3.961	EPSD;PhosphoSitePlus	COSMIC	6.007	Loss
CMGC_GSK_GSK3B_ST	Q13485	SMAD4	P49841	GSK3B	T273	A274E	274	Missense	proximal	1	no	7.721	7.620	PhosphoSitePlus;EPSD	COSMIC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	Q13485	SMAD4	P49841	GSK3B	T273	P275S	275	Missense	proximal	2	no	7.721	7.277	PhosphoSitePlus;EPSD	COSMIC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	Q13485	SMAD4	P49841	GSK3B	T273	W268L	268	Missense	distal	-5	no	7.721	7.389	PhosphoSitePlus;EPSD	COSMIC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	Q13485	SMAD4	P49841	GSK3B	T273	W268C	268	Missense	distal	-5	no	7.721	7.800	PhosphoSitePlus;EPSD	COSMIC	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	Q13485	SMAD4	P49841	GSK3B	T273	P275L	275	Missense	proximal	2	no	7.721	7.337	PhosphoSitePlus;EPSD	COSMIC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	Q13485	SMAD4	P49841	GSK3B	T273	R272S	272	Missense	proximal	-1	no	7.721	7.858	PhosphoSitePlus;EPSD	COSMIC	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	Q13485	SMAD4	P49841	GSK3B	T273	T277R	277	Missense	distal	4	no	7.721	5.552	PhosphoSitePlus;EPSD	COSMIC	6.007	Loss
CMGC_GSK_GSK3B_ST	Q13485	SMAD4	P49841	GSK3B	T273	T277S	277	Missense	distal	4	no	7.721	8.590	PhosphoSitePlus;EPSD	COSMIC	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	Q13485	SMAD4	P49841	GSK3B	T277	A274E	274	Missense	distal	-3	no	7.392	7.385	EPSD	COSMIC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	Q13485	SMAD4	P49841	GSK3B	T277	P275S	275	Missense	proximal	-2	no	7.392	7.136	EPSD	COSMIC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	Q13485	SMAD4	P49841	GSK3B	T277	P275L	275	Missense	proximal	-2	no	7.392	7.061	EPSD	COSMIC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	Q13485	SMAD4	P49841	GSK3B	T277	R272S	272	Missense	distal	-5	no	7.392	6.695	EPSD	COSMIC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	Q13485	SMAD4	P49841	GSK3B	T277	T273S	273	Missense	distal	-4	no	7.392	7.727	EPSD	COSMIC	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	Q13485	SMAD4	P49841	GSK3B	T277	P281L	281	Missense	distal	4	no	7.392	7.645	EPSD	COSMIC	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	Q13485	SMAD4	P49841	GSK3B	T277	T277R	277	Missense	central	0	yes	7.392	0.000	EPSD	COSMIC	6.007	Loss
CMGC_GSK_GSK3B_ST	P01112	HRAS	P49841	GSK3B	T35	P34S	34	Missense	proximal	-1	no	6.429	6.372	EPSD	COSMIC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	P01112	HRAS	P49841	GSK3B	T35	D33Y	33	Missense	proximal	-2	no	6.429	6.125	EPSD	COSMIC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	P01112	HRAS	P49841	GSK3B	T35	I36V	36	Missense	proximal	1	no	6.429	7.319	EPSD	COSMIC	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	P01112	HRAS	P49841	GSK3B	T35	Y32C	32	Missense	distal	-3	no	6.429	6.392	EPSD	COSMIC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	P01112	HRAS	P49841	GSK3B	T144	S145L	145	Missense	proximal	1	no	8.137	9.121	EPSD;PhosphoSitePlus	COSMIC	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	P01112	HRAS	P49841	GSK3B	T144	A146T	146	Missense	proximal	2	no	8.137	8.255	EPSD;PhosphoSitePlus	COSMIC	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	P01112	HRAS	P49841	GSK3B	T144	Y137D	137	Missense	distal	-7	no	8.137	8.111	EPSD;PhosphoSitePlus	COSMIC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	P01112	HRAS	P49841	GSK3B	T144	T144I	144	Missense	central	0	yes	8.137	0.000	EPSD;PhosphoSitePlus	COSMIC	6.007	Loss
CMGC_GSK_GSK3B_ST	P01112	HRAS	P49841	GSK3B	T144	T148A	148	Missense	distal	4	no	8.137	6.594	EPSD;PhosphoSitePlus	COSMIC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	P17661	DES	P49841	GSK3B	S32	A38T	38	Missense	distal	6	no	6.826	6.830	PhosphoSitePlus;EPSD	COSMIC	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	P17661	DES	P49841	GSK3B	S42	S42Y	42	Missense	central	0	yes	8.717	0.000	EPSD	COSMIC	6.007	Loss
CMGC_GSK_GSK3B_ST	P17661	DES	P49841	GSK3B	S42	A38T	38	Missense	distal	-4	no	8.717	9.541	EPSD	COSMIC	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	P17661	DES	P49841	GSK3B	S42	G41S	41	Missense	proximal	-1	no	8.717	8.710	EPSD	COSMIC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	P17661	DES	P49841	GSK3B	S46	S42Y	42	Missense	distal	-4	no	6.402	5.601	EPSD	COSMIC	6.007	Loss
CMGC_GSK_GSK3B_ST	P17661	DES	P49841	GSK3B	S46	G41S	41	Missense	distal	-5	no	6.402	5.936	EPSD	COSMIC	6.007	Loss
CMGC_GSK_GSK3B_ST	P17661	DES	P49841	GSK3B	S68	G62R	62	Missense	distal	-6	no	7.718	7.645	EPSD	COSMIC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	P17661	DES	P49841	GSK3B	S68	G65S	65	Missense	distal	-3	no	7.718	7.722	EPSD	COSMIC;GDSC;CCLE	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	P17661	DES	P49841	GSK3B	S68	G64R	64	Missense	distal	-4	no	7.718	6.959	EPSD	COSMIC;CCLE	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	P17661	DES	P49841	GSK3B	S68	G65D	65	Missense	distal	-3	no	7.718	7.768	EPSD	COSMIC	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	P17661	DES	P49841	GSK3B	S72	G65S	65	Missense	distal	-7	no	8.505	8.507	EPSD	COSMIC;GDSC;CCLE	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	P17661	DES	P49841	GSK3B	S72	G65D	65	Missense	distal	-7	no	8.505	8.510	EPSD	COSMIC	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	P17661	DES	P49841	GSK3B	S432	R429Q	429	Missense	distal	-3	no	7.534	7.395	EPSD	COSMIC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	P17661	DES	P49841	GSK3B	S432	A425T	425	Missense	distal	-7	no	7.534	7.539	EPSD	COSMIC	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	P17661	DES	P49841	GSK3B	S432	P433L	433	Missense	proximal	1	no	7.534	4.674	EPSD	COSMIC	6.007	Loss
CMGC_GSK_GSK3B_ST	P17661	DES	P49841	GSK3B	T453	S460N	460	Missense	distal	7	no	5.968	6.091	EPSD	COSMIC	6.007	Gain
CMGC_GSK_GSK3B_ST	P35222	CTNNB1	P49841	GSK3B	S29	I35T	35	Missense	distal	6	no	6.757	6.759	EPSD	COSMIC	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	P35222	CTNNB1	P49841	GSK3B	S29	Q28E	28	Missense	proximal	-1	no	6.757	6.852	EPSD	COSMIC	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	P35222	CTNNB1	P49841	GSK3B	S29	D32E	32	Missense	distal	3	no	6.757	6.642	EPSD	COSMIC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	P35222	CTNNB1	P49841	GSK3B	S29	H36R	36	Missense	distal	7	no	6.757	6.569	EPSD	COSMIC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	P35222	CTNNB1	P49841	GSK3B	S29	G34L	34	Missense	distal	5	no	6.757	6.388	EPSD	COSMIC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	P35222	CTNNB1	P49841	GSK3B	S29	V22I	22	Missense	distal	-7	no	6.757	6.763	EPSD	COSMIC	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	P35222	CTNNB1	P49841	GSK3B	S29	S33L	33	Missense	distal	4	no	6.757	4.039	EPSD	COSMIC;CCLE	6.007	Loss
CMGC_GSK_GSK3B_ST	P35222	CTNNB1	P49841	GSK3B	S29	S29P	29	Missense	central	0	yes	6.757	0.000	EPSD	COSMIC	6.007	Loss
CMGC_GSK_GSK3B_ST	P35222	CTNNB1	P49841	GSK3B	S29	L31P	31	Missense	proximal	2	no	6.757	7.141	EPSD	COSMIC	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	P35222	CTNNB1	P49841	GSK3B	S29	Q27H	27	Missense	proximal	-2	no	6.757	6.696	EPSD	COSMIC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	P35222	CTNNB1	P49841	GSK3B	S29	S33N	33	Missense	distal	4	no	6.757	3.146	EPSD	COSMIC	6.007	Loss
CMGC_GSK_GSK3B_ST	P35222	CTNNB1	P49841	GSK3B	S29	H36Y	36	Missense	distal	7	no	6.757	6.573	EPSD	COSMIC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	P35222	CTNNB1	P49841	GSK3B	S29	S23N	23	Missense	distal	-6	no	6.757	6.754	EPSD	COSMIC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	P35222	CTNNB1	P49841	GSK3B	S29	S29F	29	Missense	central	0	yes	6.757	0.000	EPSD	COSMIC	6.007	Loss
CMGC_GSK_GSK3B_ST	P35222	CTNNB1	P49841	GSK3B	S29	Y30C	30	Missense	proximal	1	no	6.757	5.752	EPSD	COSMIC	6.007	Loss
CMGC_GSK_GSK3B_ST	P35222	CTNNB1	P49841	GSK3B	S29	S29Y	29	Missense	central	0	yes	6.757	0.000	EPSD	COSMIC	6.007	Loss
CMGC_GSK_GSK3B_ST	P35222	CTNNB1	P49841	GSK3B	S29	S23R	23	Missense	distal	-6	no	6.757	6.699	EPSD	COSMIC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	P35222	CTNNB1	P49841	GSK3B	S29	H24Y	24	Missense	distal	-5	no	6.757	7.242	EPSD	COSMIC	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	P35222	CTNNB1	P49841	GSK3B	S29	W25R	25	Missense	distal	-4	no	6.757	7.587	EPSD	COSMIC	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	P35222	CTNNB1	P49841	GSK3B	S29	V22A	22	Missense	distal	-7	no	6.757	6.758	EPSD	COSMIC	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	P35222	CTNNB1	P49841	GSK3B	S29	I35M	35	Missense	distal	6	no	6.757	6.752	EPSD	COSMIC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	P35222	CTNNB1	P49841	GSK3B	S29	W25L	25	Missense	distal	-4	no	6.757	7.423	EPSD	COSMIC	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	P35222	CTNNB1	P49841	GSK3B	S29	H24Q	24	Missense	distal	-5	no	6.757	6.733	EPSD	COSMIC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	P35222	CTNNB1	P49841	GSK3B	S29	S23G	23	Missense	distal	-6	no	6.757	6.773	EPSD	COSMIC	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	P35222	CTNNB1	P49841	GSK3B	S29	V22G	22	Missense	distal	-7	no	6.757	6.733	EPSD	COSMIC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	P35222	CTNNB1	P49841	GSK3B	S29	S29A	29	Missense	central	0	yes	6.757	0.000	EPSD	COSMIC	6.007	Loss
CMGC_GSK_GSK3B_ST	P35222	CTNNB1	P49841	GSK3B	S29	G34A	34	Missense	distal	5	no	6.757	6.639	EPSD	COSMIC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	P35222	CTNNB1	P49841	GSK3B	S29	L31W	31	Missense	proximal	2	no	6.757	6.285	EPSD	COSMIC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	P35222	CTNNB1	P49841	GSK3B	S29	G34I	34	Missense	distal	5	no	6.757	6.048	EPSD	COSMIC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	P35222	CTNNB1	P49841	GSK3B	S29	I35N	35	Missense	distal	6	no	6.757	6.751	EPSD	COSMIC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	P35222	CTNNB1	P49841	GSK3B	S29	D32C	32	Missense	distal	3	no	6.757	6.446	EPSD	COSMIC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	P35222	CTNNB1	P49841	GSK3B	S29	Y30S	30	Missense	proximal	1	no	6.757	6.230	EPSD	COSMIC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	P35222	CTNNB1	P49841	GSK3B	S29	L31M	31	Missense	proximal	2	no	6.757	6.126	EPSD	COSMIC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	P35222	CTNNB1	P49841	GSK3B	S29	H24R	24	Missense	distal	-5	no	6.757	7.287	EPSD	COSMIC	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	P35222	CTNNB1	P49841	GSK3B	S29	L31Q	31	Missense	proximal	2	no	6.757	6.920	EPSD	COSMIC	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	P35222	CTNNB1	P49841	GSK3B	S29	G34D	34	Missense	distal	5	no	6.757	6.820	EPSD	COSMIC	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	P35222	CTNNB1	P49841	GSK3B	S29	Q26R	26	Missense	distal	-3	no	6.757	6.896	EPSD	COSMIC;GDSC;CCLE	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	P35222	CTNNB1	P49841	GSK3B	S29	I35K	35	Missense	distal	6	no	6.757	6.751	EPSD	COSMIC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	P35222	CTNNB1	P49841	GSK3B	S29	Q28R	28	Missense	proximal	-1	no	6.757	6.726	EPSD	COSMIC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	P35222	CTNNB1	P49841	GSK3B	S29	D32F	32	Missense	distal	3	no	6.757	6.451	EPSD	COSMIC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	P35222	CTNNB1	P49841	GSK3B	S29	D32X	32	Missense	distal	3	no	6.757	6.472	EPSD	COSMIC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	P35222	CTNNB1	P49841	GSK3B	S29	S33K	33	Missense	distal	4	no	6.757	3.554	EPSD	COSMIC	6.007	Loss
CMGC_GSK_GSK3B_ST	P35222	CTNNB1	P49841	GSK3B	S29	I35V	35	Missense	distal	6	no	6.757	6.747	EPSD	COSMIC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	P35222	CTNNB1	P49841	GSK3B	S29	G34C	34	Missense	distal	5	no	6.757	5.474	EPSD	COSMIC	6.007	Loss
CMGC_GSK_GSK3B_ST	P35222	CTNNB1	P49841	GSK3B	S29	I35F	35	Missense	distal	6	no	6.757	6.745	EPSD	COSMIC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	P35222	CTNNB1	P49841	GSK3B	S33	A39G	39	Missense	distal	6	no	7.768	7.766	EPSD;PhosphoSitePlus	COSMIC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	P35222	CTNNB1	P49841	GSK3B	S33	G38A	38	Missense	distal	5	no	7.768	7.650	EPSD;PhosphoSitePlus	COSMIC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	P35222	CTNNB1	P49841	GSK3B	S33	T40I	40	Missense	distal	7	no	7.768	8.162	EPSD;PhosphoSitePlus	COSMIC	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	P35222	CTNNB1	P49841	GSK3B	S33	I35T	35	Missense	proximal	2	no	7.768	7.834	EPSD;PhosphoSitePlus	COSMIC	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	P35222	CTNNB1	P49841	GSK3B	S33	Q28E	28	Missense	distal	-5	no	7.768	8.056	EPSD;PhosphoSitePlus	COSMIC	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	P35222	CTNNB1	P49841	GSK3B	S33	D32E	32	Missense	proximal	-1	no	7.768	7.816	EPSD;PhosphoSitePlus	COSMIC	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	P35222	CTNNB1	P49841	GSK3B	S33	H36R	36	Missense	distal	3	no	7.768	7.425	EPSD;PhosphoSitePlus	COSMIC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	P35222	CTNNB1	P49841	GSK3B	S33	T40A	40	Missense	distal	7	no	7.768	8.174	EPSD;PhosphoSitePlus	COSMIC	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	P35222	CTNNB1	P49841	GSK3B	S33	G34L	34	Missense	proximal	1	no	7.768	8.101	EPSD;PhosphoSitePlus	COSMIC	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	P35222	CTNNB1	P49841	GSK3B	S33	S33L	33	Missense	central	0	yes	7.768	0.000	EPSD;PhosphoSitePlus	COSMIC;CCLE	6.007	Loss
CMGC_GSK_GSK3B_ST	P35222	CTNNB1	P49841	GSK3B	S33	S29P	29	Missense	distal	-4	no	7.768	7.204	EPSD;PhosphoSitePlus	COSMIC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	P35222	CTNNB1	P49841	GSK3B	S33	L31P	31	Missense	proximal	-2	no	7.768	8.098	EPSD;PhosphoSitePlus	COSMIC	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	P35222	CTNNB1	P49841	GSK3B	S33	S37L	37	Missense	distal	4	no	7.768	5.050	EPSD;PhosphoSitePlus	COSMIC	6.007	Loss
CMGC_GSK_GSK3B_ST	P35222	CTNNB1	P49841	GSK3B	S33	A39T	39	Missense	distal	6	no	7.768	7.772	EPSD;PhosphoSitePlus	COSMIC	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	P35222	CTNNB1	P49841	GSK3B	S33	Q27H	27	Missense	distal	-6	no	7.768	7.738	EPSD;PhosphoSitePlus	COSMIC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	P35222	CTNNB1	P49841	GSK3B	S33	S33N	33	Missense	central	0	yes	7.768	0.000	EPSD;PhosphoSitePlus	COSMIC	6.007	Loss
CMGC_GSK_GSK3B_ST	P35222	CTNNB1	P49841	GSK3B	S33	H36Y	36	Missense	distal	3	no	7.768	7.374	EPSD;PhosphoSitePlus	COSMIC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	P35222	CTNNB1	P49841	GSK3B	S33	S29F	29	Missense	distal	-4	no	7.768	6.614	EPSD;PhosphoSitePlus	COSMIC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	P35222	CTNNB1	P49841	GSK3B	S33	Y30C	30	Missense	distal	-3	no	7.768	7.731	EPSD;PhosphoSitePlus	COSMIC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	P35222	CTNNB1	P49841	GSK3B	S33	S29Y	29	Missense	distal	-4	no	7.768	6.967	EPSD;PhosphoSitePlus	COSMIC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	P35222	CTNNB1	P49841	GSK3B	S33	G38P	38	Missense	distal	5	no	7.768	8.679	EPSD;PhosphoSitePlus	COSMIC	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	P35222	CTNNB1	P49841	GSK3B	S33	G38D	38	Missense	distal	5	no	7.768	7.831	EPSD;PhosphoSitePlus	COSMIC	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	P35222	CTNNB1	P49841	GSK3B	S33	I35M	35	Missense	proximal	2	no	7.768	7.136	EPSD;PhosphoSitePlus	COSMIC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	P35222	CTNNB1	P49841	GSK3B	S33	T40S	40	Missense	distal	7	no	7.768	7.827	EPSD;PhosphoSitePlus	COSMIC	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	P35222	CTNNB1	P49841	GSK3B	S33	S29A	29	Missense	distal	-4	no	7.768	6.608	EPSD;PhosphoSitePlus	COSMIC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	P35222	CTNNB1	P49841	GSK3B	S33	G34A	34	Missense	proximal	1	no	7.768	7.230	EPSD;PhosphoSitePlus	COSMIC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	P35222	CTNNB1	P49841	GSK3B	S33	L31W	31	Missense	proximal	-2	no	7.768	7.932	EPSD;PhosphoSitePlus	COSMIC	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	P35222	CTNNB1	P49841	GSK3B	S33	G34I	34	Missense	proximal	1	no	7.768	7.081	EPSD;PhosphoSitePlus	COSMIC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	P35222	CTNNB1	P49841	GSK3B	S33	I35N	35	Missense	proximal	2	no	7.768	7.175	EPSD;PhosphoSitePlus	COSMIC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	P35222	CTNNB1	P49841	GSK3B	S33	D32C	32	Missense	proximal	-1	no	7.768	7.792	EPSD;PhosphoSitePlus	COSMIC	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	P35222	CTNNB1	P49841	GSK3B	S33	Y30S	30	Missense	distal	-3	no	7.768	7.628	EPSD;PhosphoSitePlus	COSMIC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	P35222	CTNNB1	P49841	GSK3B	S33	L31M	31	Missense	proximal	-2	no	7.768	7.511	EPSD;PhosphoSitePlus	COSMIC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	P35222	CTNNB1	P49841	GSK3B	S33	A39V	39	Missense	distal	6	no	7.768	7.760	EPSD;PhosphoSitePlus	COSMIC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	P35222	CTNNB1	P49841	GSK3B	S33	L31Q	31	Missense	proximal	-2	no	7.768	7.797	EPSD;PhosphoSitePlus	COSMIC	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	P35222	CTNNB1	P49841	GSK3B	S33	G34D	34	Missense	proximal	1	no	7.768	7.859	EPSD;PhosphoSitePlus	COSMIC	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	P35222	CTNNB1	P49841	GSK3B	S33	Q26R	26	Missense	distal	-7	no	7.768	7.771	EPSD;PhosphoSitePlus	COSMIC;GDSC;CCLE	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	P35222	CTNNB1	P49841	GSK3B	S33	S37T	37	Missense	distal	4	no	7.768	6.899	EPSD;PhosphoSitePlus	COSMIC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	P35222	CTNNB1	P49841	GSK3B	S33	I35K	35	Missense	proximal	2	no	7.768	7.660	EPSD;PhosphoSitePlus	COSMIC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	P35222	CTNNB1	P49841	GSK3B	S33	Q28R	28	Missense	distal	-5	no	7.768	8.322	EPSD;PhosphoSitePlus	COSMIC	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	P35222	CTNNB1	P49841	GSK3B	S33	D32F	32	Missense	proximal	-1	no	7.768	7.697	EPSD;PhosphoSitePlus	COSMIC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	P35222	CTNNB1	P49841	GSK3B	S33	G38X	38	Missense	distal	5	no	7.768	7.323	EPSD;PhosphoSitePlus	COSMIC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	P35222	CTNNB1	P49841	GSK3B	S33	D32X	32	Missense	proximal	-1	no	7.768	7.743	EPSD;PhosphoSitePlus	COSMIC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	P35222	CTNNB1	P49841	GSK3B	S33	S33K	33	Missense	central	0	yes	7.768	0.000	EPSD;PhosphoSitePlus	COSMIC	6.007	Loss
CMGC_GSK_GSK3B_ST	P35222	CTNNB1	P49841	GSK3B	S33	I35V	35	Missense	proximal	2	no	7.768	7.438	EPSD;PhosphoSitePlus	COSMIC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	P35222	CTNNB1	P49841	GSK3B	S33	S29T	29	Missense	distal	-4	no	7.768	7.432	EPSD;PhosphoSitePlus	COSMIC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	P35222	CTNNB1	P49841	GSK3B	S33	G34C	34	Missense	proximal	1	no	7.768	6.639	EPSD;PhosphoSitePlus	COSMIC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	P35222	CTNNB1	P49841	GSK3B	S33	G38S	38	Missense	distal	5	no	7.768	7.725	EPSD;PhosphoSitePlus	COSMIC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	P35222	CTNNB1	P49841	GSK3B	S33	S37V	37	Missense	distal	4	no	7.768	5.378	EPSD;PhosphoSitePlus	COSMIC	6.007	Loss
CMGC_GSK_GSK3B_ST	P35222	CTNNB1	P49841	GSK3B	S33	I35F	35	Missense	proximal	2	no	7.768	7.363	EPSD;PhosphoSitePlus	COSMIC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	P35222	CTNNB1	P49841	GSK3B	S33	T40P	40	Missense	distal	7	no	7.768	7.764	EPSD;PhosphoSitePlus	COSMIC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	P35222	CTNNB1	P49841	GSK3B	S37	P44S	44	Missense	distal	7	no	7.839	7.902	PhosphoSitePlus;EPSD	COSMIC	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	P35222	CTNNB1	P49841	GSK3B	S37	A43V	43	Missense	distal	6	no	7.839	7.830	PhosphoSitePlus;EPSD	COSMIC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	P35222	CTNNB1	P49841	GSK3B	S37	A39G	39	Missense	proximal	2	no	7.839	7.573	PhosphoSitePlus;EPSD	COSMIC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	P35222	CTNNB1	P49841	GSK3B	S37	G38A	38	Missense	proximal	1	no	7.839	7.301	PhosphoSitePlus;EPSD	COSMIC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	P35222	CTNNB1	P49841	GSK3B	S37	T40I	40	Missense	distal	3	no	7.839	7.451	PhosphoSitePlus;EPSD	COSMIC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	P35222	CTNNB1	P49841	GSK3B	S37	P44A	44	Missense	distal	7	no	7.839	8.250	PhosphoSitePlus;EPSD	COSMIC	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	P35222	CTNNB1	P49841	GSK3B	S37	I35T	35	Missense	proximal	-2	no	7.839	7.877	PhosphoSitePlus;EPSD	COSMIC	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	P35222	CTNNB1	P49841	GSK3B	S37	T41P	41	Missense	distal	4	no	7.839	5.736	PhosphoSitePlus;EPSD	COSMIC	6.007	Loss
CMGC_GSK_GSK3B_ST	P35222	CTNNB1	P49841	GSK3B	S37	T42R	42	Missense	distal	5	no	7.839	8.178	PhosphoSitePlus;EPSD	COSMIC	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	P35222	CTNNB1	P49841	GSK3B	S37	D32E	32	Missense	distal	-5	no	7.839	7.997	PhosphoSitePlus;EPSD	COSMIC	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	P35222	CTNNB1	P49841	GSK3B	S37	H36R	36	Missense	proximal	-1	no	7.839	7.753	PhosphoSitePlus;EPSD	COSMIC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	P35222	CTNNB1	P49841	GSK3B	S37	T40A	40	Missense	distal	3	no	7.839	7.534	PhosphoSitePlus;EPSD	COSMIC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	P35222	CTNNB1	P49841	GSK3B	S37	A43T	43	Missense	distal	6	no	7.839	7.843	PhosphoSitePlus;EPSD	COSMIC	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	P35222	CTNNB1	P49841	GSK3B	S37	P44L	44	Missense	distal	7	no	7.839	7.888	PhosphoSitePlus;EPSD	COSMIC	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	P35222	CTNNB1	P49841	GSK3B	S37	G34L	34	Missense	distal	-3	no	7.839	7.852	PhosphoSitePlus;EPSD	COSMIC	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	P35222	CTNNB1	P49841	GSK3B	S37	T42I	42	Missense	distal	5	no	7.839	7.195	PhosphoSitePlus;EPSD	COSMIC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	P35222	CTNNB1	P49841	GSK3B	S37	S33L	33	Missense	distal	-4	no	7.839	6.488	PhosphoSitePlus;EPSD	COSMIC;CCLE	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	P35222	CTNNB1	P49841	GSK3B	S37	T42S	42	Missense	distal	5	no	7.839	7.861	PhosphoSitePlus;EPSD	COSMIC	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	P35222	CTNNB1	P49841	GSK3B	S37	T42K	42	Missense	distal	5	no	7.839	7.303	PhosphoSitePlus;EPSD	COSMIC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	P35222	CTNNB1	P49841	GSK3B	S37	L31P	31	Missense	distal	-6	no	7.839	7.861	PhosphoSitePlus;EPSD	COSMIC	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	P35222	CTNNB1	P49841	GSK3B	S37	S37L	37	Missense	central	0	yes	7.839	0.000	PhosphoSitePlus;EPSD	COSMIC	6.007	Loss
CMGC_GSK_GSK3B_ST	P35222	CTNNB1	P49841	GSK3B	S37	A39T	39	Missense	proximal	2	no	7.839	7.957	PhosphoSitePlus;EPSD	COSMIC	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	P35222	CTNNB1	P49841	GSK3B	S37	S33N	33	Missense	distal	-4	no	7.839	6.541	PhosphoSitePlus;EPSD	COSMIC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	P35222	CTNNB1	P49841	GSK3B	S37	H36Y	36	Missense	proximal	-1	no	7.839	7.750	PhosphoSitePlus;EPSD	COSMIC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	P35222	CTNNB1	P49841	GSK3B	S37	A43P	43	Missense	distal	6	no	7.839	7.842	PhosphoSitePlus;EPSD	COSMIC	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	P35222	CTNNB1	P49841	GSK3B	S37	Y30C	30	Missense	distal	-7	no	7.839	7.833	PhosphoSitePlus;EPSD	COSMIC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	P35222	CTNNB1	P49841	GSK3B	S37	G38P	38	Missense	proximal	1	no	7.839	11.033	PhosphoSitePlus;EPSD	COSMIC	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	P35222	CTNNB1	P49841	GSK3B	S37	G38D	38	Missense	proximal	1	no	7.839	7.929	PhosphoSitePlus;EPSD	COSMIC	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	P35222	CTNNB1	P49841	GSK3B	S37	T42A	42	Missense	distal	5	no	7.839	7.786	PhosphoSitePlus;EPSD	COSMIC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	P35222	CTNNB1	P49841	GSK3B	S37	I35M	35	Missense	proximal	-2	no	7.839	7.518	PhosphoSitePlus;EPSD	COSMIC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	P35222	CTNNB1	P49841	GSK3B	S37	T40S	40	Missense	distal	3	no	7.839	7.871	PhosphoSitePlus;EPSD	COSMIC	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	P35222	CTNNB1	P49841	GSK3B	S37	G34A	34	Missense	distal	-3	no	7.839	7.863	PhosphoSitePlus;EPSD	COSMIC	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	P35222	CTNNB1	P49841	GSK3B	S37	L31W	31	Missense	distal	-6	no	7.839	7.810	PhosphoSitePlus;EPSD	COSMIC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	P35222	CTNNB1	P49841	GSK3B	S37	T41S	41	Missense	distal	4	no	7.839	8.708	PhosphoSitePlus;EPSD	COSMIC	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	P35222	CTNNB1	P49841	GSK3B	S37	G34I	34	Missense	distal	-3	no	7.839	7.956	PhosphoSitePlus;EPSD	COSMIC	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	P35222	CTNNB1	P49841	GSK3B	S37	I35N	35	Missense	proximal	-2	no	7.839	7.621	PhosphoSitePlus;EPSD	COSMIC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	P35222	CTNNB1	P49841	GSK3B	S37	D32C	32	Missense	distal	-5	no	7.839	8.086	PhosphoSitePlus;EPSD	COSMIC	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	P35222	CTNNB1	P49841	GSK3B	S37	Y30S	30	Missense	distal	-7	no	7.839	7.810	PhosphoSitePlus;EPSD	COSMIC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	P35222	CTNNB1	P49841	GSK3B	S37	L31M	31	Missense	distal	-6	no	7.839	7.787	PhosphoSitePlus;EPSD	COSMIC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	P35222	CTNNB1	P49841	GSK3B	S37	A39V	39	Missense	proximal	2	no	7.839	7.562	PhosphoSitePlus;EPSD	COSMIC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	P35222	CTNNB1	P49841	GSK3B	S37	L31Q	31	Missense	distal	-6	no	7.839	7.836	PhosphoSitePlus;EPSD	COSMIC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	P35222	CTNNB1	P49841	GSK3B	S37	G34D	34	Missense	distal	-3	no	7.839	7.889	PhosphoSitePlus;EPSD	COSMIC	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	P35222	CTNNB1	P49841	GSK3B	S37	I35K	35	Missense	proximal	-2	no	7.839	7.715	PhosphoSitePlus;EPSD	COSMIC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	P35222	CTNNB1	P49841	GSK3B	S37	D32F	32	Missense	distal	-5	no	7.839	8.126	PhosphoSitePlus;EPSD	COSMIC	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	P35222	CTNNB1	P49841	GSK3B	S37	G38X	38	Missense	proximal	1	no	7.839	7.217	PhosphoSitePlus;EPSD	COSMIC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	P35222	CTNNB1	P49841	GSK3B	S37	D32X	32	Missense	distal	-5	no	7.839	7.973	PhosphoSitePlus;EPSD	COSMIC	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	P35222	CTNNB1	P49841	GSK3B	S37	S33K	33	Missense	distal	-4	no	7.839	6.974	PhosphoSitePlus;EPSD	COSMIC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	P35222	CTNNB1	P49841	GSK3B	S37	I35V	35	Missense	proximal	-2	no	7.839	7.817	PhosphoSitePlus;EPSD	COSMIC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	P35222	CTNNB1	P49841	GSK3B	S37	G34C	34	Missense	distal	-3	no	7.839	7.946	PhosphoSitePlus;EPSD	COSMIC	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	P35222	CTNNB1	P49841	GSK3B	S37	G38S	38	Missense	proximal	1	no	7.839	7.188	PhosphoSitePlus;EPSD	COSMIC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	P35222	CTNNB1	P49841	GSK3B	S37	S37V	37	Missense	central	0	yes	7.839	0.000	PhosphoSitePlus;EPSD	COSMIC	6.007	Loss
CMGC_GSK_GSK3B_ST	P35222	CTNNB1	P49841	GSK3B	S37	P44I	44	Missense	distal	7	no	7.839	8.237	PhosphoSitePlus;EPSD	COSMIC	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	P35222	CTNNB1	P49841	GSK3B	S37	I35F	35	Missense	proximal	-2	no	7.839	7.519	PhosphoSitePlus;EPSD	COSMIC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	P35222	CTNNB1	P49841	GSK3B	S37	T40P	40	Missense	distal	3	no	7.839	7.889	PhosphoSitePlus;EPSD	COSMIC	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	P35222	CTNNB1	P49841	GSK3B	T40	P44S	44	Missense	distal	4	no	3.709	6.680	EPSD	COSMIC	6.007	Gain
CMGC_GSK_GSK3B_ST	P35222	CTNNB1	P49841	GSK3B	T40	T41P	41	Missense	proximal	1	no	3.709	6.900	EPSD	COSMIC	6.007	Gain
CMGC_GSK_GSK3B_ST	P35222	CTNNB1	P49841	GSK3B	T41	S45T	45	Missense	distal	4	no	7.890	7.022	EPSD;PhosphoSitePlus	COSMIC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	P35222	CTNNB1	P49841	GSK3B	T41	P44S	44	Missense	distal	3	no	7.890	7.873	EPSD;PhosphoSitePlus	COSMIC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	P35222	CTNNB1	P49841	GSK3B	T41	A43V	43	Missense	proximal	2	no	7.890	7.614	EPSD;PhosphoSitePlus	COSMIC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	P35222	CTNNB1	P49841	GSK3B	T41	G48D	48	Missense	distal	7	no	7.890	7.925	EPSD;PhosphoSitePlus	COSMIC	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	P35222	CTNNB1	P49841	GSK3B	T41	A39G	39	Missense	proximal	-2	no	7.890	8.107	EPSD;PhosphoSitePlus	COSMIC	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	P35222	CTNNB1	P49841	GSK3B	T41	G38A	38	Missense	distal	-3	no	7.890	7.915	EPSD;PhosphoSitePlus	COSMIC	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	P35222	CTNNB1	P49841	GSK3B	T41	T40I	40	Missense	proximal	-1	no	7.890	7.816	EPSD;PhosphoSitePlus	COSMIC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	P35222	CTNNB1	P49841	GSK3B	T41	P44A	44	Missense	distal	3	no	7.890	7.536	EPSD;PhosphoSitePlus	COSMIC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	P35222	CTNNB1	P49841	GSK3B	T41	I35T	35	Missense	distal	-6	no	7.890	7.895	EPSD;PhosphoSitePlus	COSMIC	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	P35222	CTNNB1	P49841	GSK3B	T41	T41P	41	Missense	central	0	yes	7.890	0.000	EPSD;PhosphoSitePlus	COSMIC	6.007	Loss
CMGC_GSK_GSK3B_ST	P35222	CTNNB1	P49841	GSK3B	T41	T42R	42	Missense	proximal	1	no	7.890	8.761	EPSD;PhosphoSitePlus	COSMIC	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	P35222	CTNNB1	P49841	GSK3B	T41	S45A	45	Missense	distal	4	no	7.890	5.479	EPSD;PhosphoSitePlus	COSMIC	6.007	Loss
CMGC_GSK_GSK3B_ST	P35222	CTNNB1	P49841	GSK3B	T41	H36R	36	Missense	distal	-5	no	7.890	8.421	EPSD;PhosphoSitePlus	COSMIC	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	P35222	CTNNB1	P49841	GSK3B	T41	G48S	48	Missense	distal	7	no	7.890	7.871	EPSD;PhosphoSitePlus	COSMIC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	P35222	CTNNB1	P49841	GSK3B	T41	T40A	40	Missense	proximal	-1	no	7.890	7.811	EPSD;PhosphoSitePlus	COSMIC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	P35222	CTNNB1	P49841	GSK3B	T41	A43T	43	Missense	proximal	2	no	7.890	8.009	EPSD;PhosphoSitePlus	COSMIC	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	P35222	CTNNB1	P49841	GSK3B	T41	P44L	44	Missense	distal	3	no	7.890	7.572	EPSD;PhosphoSitePlus	COSMIC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	P35222	CTNNB1	P49841	GSK3B	T41	G34L	34	Missense	distal	-7	no	7.890	7.893	EPSD;PhosphoSitePlus	COSMIC	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	P35222	CTNNB1	P49841	GSK3B	T41	T42I	42	Missense	proximal	1	no	7.890	7.200	EPSD;PhosphoSitePlus	COSMIC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	P35222	CTNNB1	P49841	GSK3B	T41	T42S	42	Missense	proximal	1	no	7.890	7.237	EPSD;PhosphoSitePlus	COSMIC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	P35222	CTNNB1	P49841	GSK3B	T41	T42K	42	Missense	proximal	1	no	7.890	7.535	EPSD;PhosphoSitePlus	COSMIC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	P35222	CTNNB1	P49841	GSK3B	T41	S47G	47	Missense	distal	6	no	7.890	7.887	EPSD;PhosphoSitePlus	COSMIC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	P35222	CTNNB1	P49841	GSK3B	T41	G48V	48	Missense	distal	7	no	7.890	8.296	EPSD;PhosphoSitePlus	COSMIC	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	P35222	CTNNB1	P49841	GSK3B	T41	S47N	47	Missense	distal	6	no	7.890	7.884	EPSD;PhosphoSitePlus	COSMIC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	P35222	CTNNB1	P49841	GSK3B	T41	S37L	37	Missense	distal	-4	no	7.890	6.540	EPSD;PhosphoSitePlus	COSMIC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	P35222	CTNNB1	P49841	GSK3B	T41	A39T	39	Missense	proximal	-2	no	7.890	8.252	EPSD;PhosphoSitePlus	COSMIC	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	P35222	CTNNB1	P49841	GSK3B	T41	H36Y	36	Missense	distal	-5	no	7.890	8.376	EPSD;PhosphoSitePlus	COSMIC	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	P35222	CTNNB1	P49841	GSK3B	T41	A43P	43	Missense	proximal	2	no	7.890	8.327	EPSD;PhosphoSitePlus	COSMIC	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	P35222	CTNNB1	P49841	GSK3B	T41	L46P	46	Missense	distal	5	no	7.890	9.171	EPSD;PhosphoSitePlus	COSMIC	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	P35222	CTNNB1	P49841	GSK3B	T41	G38P	38	Missense	distal	-3	no	7.890	7.778	EPSD;PhosphoSitePlus	COSMIC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	P35222	CTNNB1	P49841	GSK3B	T41	G38D	38	Missense	distal	-3	no	7.890	7.941	EPSD;PhosphoSitePlus	COSMIC	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	P35222	CTNNB1	P49841	GSK3B	T41	T42A	42	Missense	proximal	1	no	7.890	7.349	EPSD;PhosphoSitePlus	COSMIC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	P35222	CTNNB1	P49841	GSK3B	T41	L46V	46	Missense	distal	5	no	7.890	7.716	EPSD;PhosphoSitePlus	COSMIC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	P35222	CTNNB1	P49841	GSK3B	T41	S47L	47	Missense	distal	6	no	7.890	7.886	EPSD;PhosphoSitePlus	COSMIC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	P35222	CTNNB1	P49841	GSK3B	T41	I35M	35	Missense	distal	-6	no	7.890	7.900	EPSD;PhosphoSitePlus	COSMIC	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	P35222	CTNNB1	P49841	GSK3B	T41	T40S	40	Missense	proximal	-1	no	7.890	7.965	EPSD;PhosphoSitePlus	COSMIC	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	P35222	CTNNB1	P49841	GSK3B	T41	L46M	46	Missense	distal	5	no	7.890	8.078	EPSD;PhosphoSitePlus	COSMIC	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	P35222	CTNNB1	P49841	GSK3B	T41	G34A	34	Missense	distal	-7	no	7.890	7.915	EPSD;PhosphoSitePlus	COSMIC	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	P35222	CTNNB1	P49841	GSK3B	T41	S47T	47	Missense	distal	6	no	7.890	7.893	EPSD;PhosphoSitePlus	COSMIC	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	P35222	CTNNB1	P49841	GSK3B	T41	G34I	34	Missense	distal	-7	no	7.890	7.920	EPSD;PhosphoSitePlus	COSMIC	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	P35222	CTNNB1	P49841	GSK3B	T41	I35N	35	Missense	distal	-6	no	7.890	7.951	EPSD;PhosphoSitePlus	COSMIC	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	P35222	CTNNB1	P49841	GSK3B	T41	T42Q	42	Missense	proximal	1	no	7.890	7.813	EPSD;PhosphoSitePlus	COSMIC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	P35222	CTNNB1	P49841	GSK3B	T41	S47C	47	Missense	distal	6	no	7.890	7.877	EPSD;PhosphoSitePlus	COSMIC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	P35222	CTNNB1	P49841	GSK3B	T41	S47R	47	Missense	distal	6	no	7.890	7.886	EPSD;PhosphoSitePlus	COSMIC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	P35222	CTNNB1	P49841	GSK3B	T41	A39V	39	Missense	proximal	-2	no	7.890	8.192	EPSD;PhosphoSitePlus	COSMIC	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	P35222	CTNNB1	P49841	GSK3B	T41	S45E	45	Missense	distal	4	no	7.890	5.870	EPSD;PhosphoSitePlus	COSMIC	6.007	Loss
CMGC_GSK_GSK3B_ST	P35222	CTNNB1	P49841	GSK3B	T41	G34D	34	Missense	distal	-7	no	7.890	7.895	EPSD;PhosphoSitePlus	COSMIC	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	P35222	CTNNB1	P49841	GSK3B	T41	S37T	37	Missense	distal	-4	no	7.890	7.555	EPSD;PhosphoSitePlus	COSMIC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	P35222	CTNNB1	P49841	GSK3B	T41	I35K	35	Missense	distal	-6	no	7.890	7.891	EPSD;PhosphoSitePlus	COSMIC	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	P35222	CTNNB1	P49841	GSK3B	T41	S45N	45	Missense	distal	4	no	7.890	4.280	EPSD;PhosphoSitePlus	COSMIC	6.007	Loss
CMGC_GSK_GSK3B_ST	P35222	CTNNB1	P49841	GSK3B	T41	G38X	38	Missense	distal	-3	no	7.890	7.959	EPSD;PhosphoSitePlus	COSMIC	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	P35222	CTNNB1	P49841	GSK3B	T41	L46Q	46	Missense	distal	5	no	7.890	8.194	EPSD;PhosphoSitePlus	COSMIC	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	P35222	CTNNB1	P49841	GSK3B	T41	I35V	35	Missense	distal	-6	no	7.890	7.886	EPSD;PhosphoSitePlus	COSMIC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	P35222	CTNNB1	P49841	GSK3B	T41	S45X	45	Missense	distal	4	no	7.890	4.669	EPSD;PhosphoSitePlus	COSMIC	6.007	Loss
CMGC_GSK_GSK3B_ST	P35222	CTNNB1	P49841	GSK3B	T41	G34C	34	Missense	distal	-7	no	7.890	7.915	EPSD;PhosphoSitePlus	COSMIC	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	P35222	CTNNB1	P49841	GSK3B	T41	G38S	38	Missense	distal	-3	no	7.890	7.894	EPSD;PhosphoSitePlus	COSMIC	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	P35222	CTNNB1	P49841	GSK3B	T41	S37V	37	Missense	distal	-4	no	7.890	6.657	EPSD;PhosphoSitePlus	COSMIC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	P35222	CTNNB1	P49841	GSK3B	T41	P44I	44	Missense	distal	3	no	7.890	7.452	EPSD;PhosphoSitePlus	COSMIC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	P35222	CTNNB1	P49841	GSK3B	T41	I35F	35	Missense	distal	-6	no	7.890	7.900	EPSD;PhosphoSitePlus	COSMIC	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	P35222	CTNNB1	P49841	GSK3B	T41	S47Y	47	Missense	distal	6	no	7.890	7.884	EPSD;PhosphoSitePlus	COSMIC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	P35222	CTNNB1	P49841	GSK3B	T41	T40P	40	Missense	proximal	-1	no	7.890	8.022	EPSD;PhosphoSitePlus	COSMIC	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	P35222	CTNNB1	P49841	GSK3B	T42	A43P	43	Missense	proximal	1	no	2.854	6.586	EPSD	COSMIC	6.007	Gain
CMGC_GSK_GSK3B_ST	P35222	CTNNB1	P49841	GSK3B	S45	P44S	44	Missense	proximal	-1	no	6.277	6.221	EPSD	COSMIC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	P35222	CTNNB1	P49841	GSK3B	S45	A43V	43	Missense	proximal	-2	no	6.277	6.579	EPSD	COSMIC	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	P35222	CTNNB1	P49841	GSK3B	S45	G48D	48	Missense	distal	3	no	6.277	6.328	EPSD	COSMIC	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	P35222	CTNNB1	P49841	GSK3B	S45	A39G	39	Missense	distal	-6	no	6.277	6.283	EPSD	COSMIC	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	P35222	CTNNB1	P49841	GSK3B	S45	N51T	51	Missense	distal	6	no	6.277	6.286	EPSD	COSMIC	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	P35222	CTNNB1	P49841	GSK3B	S45	P52L	52	Missense	distal	7	no	6.277	6.326	EPSD	COSMIC	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	P35222	CTNNB1	P49841	GSK3B	S45	N51S	51	Missense	distal	6	no	6.277	6.284	EPSD	COSMIC	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	P35222	CTNNB1	P49841	GSK3B	S45	G38A	38	Missense	distal	-7	no	6.277	6.302	EPSD	COSMIC	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	P35222	CTNNB1	P49841	GSK3B	S45	T40I	40	Missense	distal	-5	no	6.277	6.461	EPSD	COSMIC	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	P35222	CTNNB1	P49841	GSK3B	S45	P44A	44	Missense	proximal	-1	no	6.277	6.066	EPSD	COSMIC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	P35222	CTNNB1	P49841	GSK3B	S45	T41P	41	Missense	distal	-4	no	6.277	6.049	EPSD	COSMIC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	P35222	CTNNB1	P49841	GSK3B	S45	K49R	49	Missense	distal	4	no	6.277	6.442	EPSD	COSMIC	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	P35222	CTNNB1	P49841	GSK3B	S45	T42R	42	Missense	distal	-3	no	6.277	6.421	EPSD	COSMIC	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	P35222	CTNNB1	P49841	GSK3B	S45	S45A	45	Missense	central	0	yes	6.277	0.000	EPSD	COSMIC	6.007	Loss
CMGC_GSK_GSK3B_ST	P35222	CTNNB1	P49841	GSK3B	S45	G48S	48	Missense	distal	3	no	6.277	6.234	EPSD	COSMIC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	P35222	CTNNB1	P49841	GSK3B	S45	T40A	40	Missense	distal	-5	no	6.277	6.266	EPSD	COSMIC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	P35222	CTNNB1	P49841	GSK3B	S45	A43T	43	Missense	proximal	-2	no	6.277	6.639	EPSD	COSMIC	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	P35222	CTNNB1	P49841	GSK3B	S45	P44L	44	Missense	proximal	-1	no	6.277	6.146	EPSD	COSMIC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	P35222	CTNNB1	P49841	GSK3B	S45	T42I	42	Missense	distal	-3	no	6.277	6.366	EPSD	COSMIC	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	P35222	CTNNB1	P49841	GSK3B	S45	T42S	42	Missense	distal	-3	no	6.277	6.252	EPSD	COSMIC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	P35222	CTNNB1	P49841	GSK3B	S45	T42K	42	Missense	distal	-3	no	6.277	6.276	EPSD	COSMIC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	P35222	CTNNB1	P49841	GSK3B	S45	S47G	47	Missense	proximal	2	no	6.277	6.019	EPSD	COSMIC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	P35222	CTNNB1	P49841	GSK3B	S45	G48V	48	Missense	distal	3	no	6.277	6.026	EPSD	COSMIC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	P35222	CTNNB1	P49841	GSK3B	S45	S47N	47	Missense	proximal	2	no	6.277	5.745	EPSD	COSMIC	6.007	Loss
CMGC_GSK_GSK3B_ST	P35222	CTNNB1	P49841	GSK3B	S45	A39T	39	Missense	distal	-6	no	6.277	6.209	EPSD	COSMIC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	P35222	CTNNB1	P49841	GSK3B	S45	K49T	49	Missense	distal	4	no	6.277	8.611	EPSD	COSMIC	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	P35222	CTNNB1	P49841	GSK3B	S45	G50D	50	Missense	distal	5	no	6.277	6.341	EPSD	COSMIC	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	P35222	CTNNB1	P49841	GSK3B	S45	A43P	43	Missense	proximal	-2	no	6.277	6.868	EPSD	COSMIC	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	P35222	CTNNB1	P49841	GSK3B	S45	L46P	46	Missense	proximal	1	no	6.277	9.138	EPSD	COSMIC	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	P35222	CTNNB1	P49841	GSK3B	S45	G38P	38	Missense	distal	-7	no	6.277	6.278	EPSD	COSMIC	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	P35222	CTNNB1	P49841	GSK3B	S45	G38D	38	Missense	distal	-7	no	6.277	6.282	EPSD	COSMIC	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	P35222	CTNNB1	P49841	GSK3B	S45	T42A	42	Missense	distal	-3	no	6.277	6.273	EPSD	COSMIC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	P35222	CTNNB1	P49841	GSK3B	S45	L46V	46	Missense	proximal	1	no	6.277	6.147	EPSD	COSMIC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	P35222	CTNNB1	P49841	GSK3B	S45	S47L	47	Missense	proximal	2	no	6.277	6.337	EPSD	COSMIC	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	P35222	CTNNB1	P49841	GSK3B	S45	T40S	40	Missense	distal	-5	no	6.277	5.988	EPSD	COSMIC	6.007	Loss
CMGC_GSK_GSK3B_ST	P35222	CTNNB1	P49841	GSK3B	S45	K49L	49	Missense	distal	4	no	6.277	6.762	EPSD	COSMIC	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	P35222	CTNNB1	P49841	GSK3B	S45	L46M	46	Missense	proximal	1	no	6.277	5.551	EPSD	COSMIC	6.007	Loss
CMGC_GSK_GSK3B_ST	P35222	CTNNB1	P49841	GSK3B	S45	S47T	47	Missense	proximal	2	no	6.277	6.404	EPSD	COSMIC	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	P35222	CTNNB1	P49841	GSK3B	S45	T41S	41	Missense	distal	-4	no	6.277	6.613	EPSD	COSMIC	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	P35222	CTNNB1	P49841	GSK3B	S45	T42Q	42	Missense	distal	-3	no	6.277	6.282	EPSD	COSMIC	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	P35222	CTNNB1	P49841	GSK3B	S45	S47C	47	Missense	proximal	2	no	6.277	5.785	EPSD	COSMIC	6.007	Loss
CMGC_GSK_GSK3B_ST	P35222	CTNNB1	P49841	GSK3B	S45	K49E	49	Missense	distal	4	no	6.277	7.459	EPSD	COSMIC	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	P35222	CTNNB1	P49841	GSK3B	S45	S47R	47	Missense	proximal	2	no	6.277	6.296	EPSD	COSMIC	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	P35222	CTNNB1	P49841	GSK3B	S45	A39V	39	Missense	distal	-6	no	6.277	6.199	EPSD	COSMIC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	P35222	CTNNB1	P49841	GSK3B	S45	S45E	45	Missense	central	0	yes	6.277	0.000	EPSD	COSMIC	6.007	Loss
CMGC_GSK_GSK3B_ST	P35222	CTNNB1	P49841	GSK3B	S45	G50S	50	Missense	distal	5	no	6.277	6.235	EPSD	COSMIC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	P35222	CTNNB1	P49841	GSK3B	S45	S45N	45	Missense	central	0	yes	6.277	0.000	EPSD	COSMIC	6.007	Loss
CMGC_GSK_GSK3B_ST	P35222	CTNNB1	P49841	GSK3B	S45	G38X	38	Missense	distal	-7	no	6.277	6.300	EPSD	COSMIC	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	P35222	CTNNB1	P49841	GSK3B	S45	L46Q	46	Missense	proximal	1	no	6.277	5.870	EPSD	COSMIC	6.007	Loss
CMGC_GSK_GSK3B_ST	P35222	CTNNB1	P49841	GSK3B	S45	S45X	45	Missense	central	0	yes	6.277	0.000	EPSD	COSMIC	6.007	Loss
CMGC_GSK_GSK3B_ST	P35222	CTNNB1	P49841	GSK3B	S45	G38S	38	Missense	distal	-7	no	6.277	6.280	EPSD	COSMIC	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	P35222	CTNNB1	P49841	GSK3B	S45	P44I	44	Missense	proximal	-1	no	6.277	6.072	EPSD	COSMIC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	P35222	CTNNB1	P49841	GSK3B	S45	S47I	47	Missense	proximal	2	no	6.277	6.338	EPSD	COSMIC	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	P35222	CTNNB1	P49841	GSK3B	S45	S47Y	47	Missense	proximal	2	no	6.277	6.045	EPSD	COSMIC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	P35222	CTNNB1	P49841	GSK3B	S45	T40P	40	Missense	distal	-5	no	6.277	5.832	EPSD	COSMIC	6.007	Loss
CMGC_GSK_GSK3B_ST	P35222	CTNNB1	P49841	GSK3B	S47	N51T	51	Missense	distal	4	no	4.419	7.161	EPSD	COSMIC	6.007	Gain
CMGC_GSK_GSK3B_ST	P35222	CTNNB1	P49841	GSK3B	S47	N51S	51	Missense	distal	4	no	4.419	8.029	EPSD	COSMIC	6.007	Gain
CMGC_GSK_GSK3B_ST	P35222	CTNNB1	P49841	GSK3B	T75	Q76R	76	Missense	proximal	1	no	5.910	6.859	EPSD	COSMIC	6.007	Gain
CMGC_GSK_GSK3B_ST	P35222	CTNNB1	P49841	GSK3B	S191	P192S	192	Missense	proximal	1	no	6.205	2.361	EPSD	COSMIC	6.007	Loss
CMGC_GSK_GSK3B_ST	P35222	CTNNB1	P49841	GSK3B	S191	A187T	187	Missense	distal	-4	no	6.205	7.030	EPSD	COSMIC	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	P35222	CTNNB1	P49841	GSK3B	S191	R190C	190	Missense	proximal	-1	no	6.205	6.307	EPSD	COSMIC	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	P35222	CTNNB1	P49841	GSK3B	S191	A187D	187	Missense	distal	-4	no	6.205	6.765	EPSD	COSMIC	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	P35222	CTNNB1	P49841	GSK3B	S191	P192H	192	Missense	proximal	1	no	6.205	2.505	EPSD	COSMIC	6.007	Loss
CMGC_GSK_GSK3B_ST	P35222	CTNNB1	P49841	GSK3B	S191	I188M	188	Missense	distal	-3	no	6.205	6.064	EPSD	COSMIC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	P35222	CTNNB1	P49841	GSK3B	S191	R190H	190	Missense	proximal	-1	no	6.205	6.291	EPSD	COSMIC	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	P35222	CTNNB1	P49841	GSK3B	S191	I198L	198	Missense	distal	7	no	6.205	5.856	EPSD	COSMIC	6.007	Loss
CMGC_GSK_GSK3B_ST	P35222	CTNNB1	P49841	GSK3B	S191	A187V	187	Missense	distal	-4	no	6.205	6.132	EPSD	COSMIC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	P35222	CTNNB1	P49841	GSK3B	S191	R185K	185	Missense	distal	-6	no	6.205	6.200	EPSD	COSMIC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	P35222	CTNNB1	P49841	GSK3B	S246	M243T	243	Missense	distal	-3	no	10.072	10.125	EPSD	COSMIC	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	P35222	CTNNB1	P49841	GSK3B	S246	S246L	246	Missense	central	0	yes	10.072	0.000	EPSD	COSMIC	6.007	Loss
CMGC_GSK_GSK3B_ST	P35222	CTNNB1	P49841	GSK3B	S246	G245A	245	Missense	proximal	-1	no	10.072	9.911	EPSD	COSMIC;GDSC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	P35222	CTNNB1	P49841	GSK3B	S246	G245D	245	Missense	proximal	-1	no	10.072	10.005	EPSD	COSMIC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	P35222	CTNNB1	P49841	GSK3B	S246	A239V	239	Missense	distal	-7	no	10.072	10.071	EPSD	COSMIC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	P35222	CTNNB1	P49841	GSK3B	S246	K242E	242	Missense	distal	-4	no	10.072	10.339	EPSD	COSMIC	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	P35222	CTNNB1	P49841	GSK3B	S246	A239G	239	Missense	distal	-7	no	10.072	10.048	EPSD	COSMIC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	P35222	CTNNB1	P49841	GSK3B	T547	A543T	543	Missense	distal	-4	no	5.958	6.782	EPSD	COSMIC	6.007	Gain
CMGC_GSK_GSK3B_ST	P35222	CTNNB1	P49841	GSK3B	T547	R550H	550	Missense	distal	3	no	5.958	6.300	EPSD	COSMIC	6.007	Gain
CMGC_GSK_GSK3B_ST	P35222	CTNNB1	P49841	GSK3B	T547	R550L	550	Missense	distal	3	no	5.958	6.028	EPSD	COSMIC	6.007	Gain
CMGC_GSK_GSK3B_ST	P35222	CTNNB1	P49841	GSK3B	T547	D546E	546	Missense	proximal	-1	no	5.958	6.007	EPSD	COSMIC	6.007	Gain
CMGC_GSK_GSK3B_ST	P35222	CTNNB1	P49841	GSK3B	T547	R550Q	550	Missense	distal	3	no	5.958	6.291	EPSD	COSMIC	6.007	Gain
CMGC_GSK_GSK3B_ST	P35222	CTNNB1	P49841	GSK3B	S605	V600G	600	Missense	distal	-5	no	6.798	6.685	EPSD	COSMIC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	P35222	CTNNB1	P49841	GSK3B	S605	R612T	612	Missense	distal	7	no	6.798	6.301	EPSD	COSMIC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	P35222	CTNNB1	P49841	GSK3B	S605	V600L	600	Missense	distal	-5	no	6.798	6.327	EPSD	COSMIC;GDSC;CCLE	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	P35222	CTNNB1	P49841	GSK3B	S605	V600A	600	Missense	distal	-5	no	6.798	6.496	EPSD	COSMIC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	P35222	CTNNB1	P49841	GSK3B	S605	F599L	599	Missense	distal	-6	no	6.798	6.850	EPSD	COSMIC	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	P35222	CTNNB1	P49841	GSK3B	S605	Q611R	611	Missense	distal	6	no	6.798	6.797	EPSD	COSMIC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	P35222	CTNNB1	P49841	GSK3B	S605	L603R	603	Missense	proximal	-2	no	6.798	6.757	EPSD	COSMIC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	P35222	CTNNB1	P49841	GSK3B	S605	L603Q	603	Missense	proximal	-2	no	6.798	6.827	EPSD	COSMIC	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	P35222	CTNNB1	P49841	GSK3B	S681	M688T	688	Missense	distal	7	no	7.674	7.247	EPSD	COSMIC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	P35222	CTNNB1	P49841	GSK3B	S681	S680I	680	Missense	proximal	-1	no	7.674	7.524	EPSD	COSMIC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	P35222	CTNNB1	P49841	GSK3B	S681	M688V	688	Missense	distal	7	no	7.674	7.731	EPSD	COSMIC	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	P35222	CTNNB1	P49841	GSK3B	S681	E677D	677	Missense	distal	-4	no	7.674	7.671	EPSD	COSMIC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	P35222	CTNNB1	P49841	GSK3B	S681	L678F	678	Missense	distal	-3	no	7.674	7.731	EPSD	COSMIC	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	P35222	CTNNB1	P49841	GSK3B	S681	E686G	686	Missense	distal	5	no	7.674	7.408	EPSD	COSMIC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	P21796	VDAC1	P49841	GSK3B	T42	G38E	38	Missense	distal	-4	no	7.594	7.425	EPSD	COSMIC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	P21796	VDAC1	P49841	GSK3B	T42	E36D	36	Missense	distal	-6	no	7.594	7.631	EPSD	COSMIC	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	P21796	VDAC1	P49841	GSK3B	T80	L81P	81	Missense	proximal	1	no	3.488	6.348	EPSD	COSMIC	6.007	Gain
CMGC_GSK_GSK3B_ST	P21796	VDAC1	P49841	GSK3B	S104	D100N	100	Missense	distal	-4	no	6.317	5.620	EPSD	COSMIC	6.007	Loss
CMGC_GSK_GSK3B_ST	O60346	PHLPP1	P49841	GSK3B	S151	S149W	149	Missense	proximal	-2	no	6.298	6.389	EPSD	COSMIC	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	O60346	PHLPP1	P49841	GSK3B	S317	S323P	323	Missense	distal	6	no	11.084	11.086	EPSD	COSMIC	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	O60346	PHLPP1	P49841	GSK3B	S324	S323P	323	Missense	proximal	-1	no	7.076	7.132	EPSD	COSMIC	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	O60346	PHLPP1	P49841	GSK3B	T451	S450F	450	Missense	proximal	-1	no	9.237	9.107	EPSD	COSMIC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	O60346	PHLPP1	P49841	GSK3B	S1359	V1352L	1352	Missense	distal	-7	no	8.796	8.775	EPSD;PhosphoSitePlus	COSMIC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	O60346	PHLPP1	P49841	GSK3B	S1359	V1357L	1357	Missense	proximal	-2	no	8.796	8.755	EPSD;PhosphoSitePlus	COSMIC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	O60346	PHLPP1	P49841	GSK3B	S1359	R1354H	1354	Missense	distal	-5	no	8.796	8.265	EPSD;PhosphoSitePlus	COSMIC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	O60346	PHLPP1	P49841	GSK3B	S1359	P1353S	1353	Missense	distal	-6	no	8.796	8.775	EPSD;PhosphoSitePlus	COSMIC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	O60346	PHLPP1	P49841	GSK3B	T1363	V1357L	1357	Missense	distal	-6	no	9.412	9.478	EPSD;PhosphoSitePlus	COSMIC	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	O60346	PHLPP1	P49841	GSK3B	T1363	E1367K	1367	Missense	distal	4	no	9.412	8.230	EPSD;PhosphoSitePlus	COSMIC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	O43623	SNAI2	P49841	GSK3B	S54	P55S	55	Missense	proximal	1	no	8.846	5.001	EPSD	COSMIC	6.007	Loss
CMGC_GSK_GSK3B_ST	O43623	SNAI2	P49841	GSK3B	S87	P88L	88	Missense	proximal	1	no	6.504	3.644	EPSD	COSMIC	6.007	Loss
CMGC_GSK_GSK3B_ST	O43623	SNAI2	P49841	GSK3B	S92	P88L	88	Missense	distal	-4	no	7.260	6.473	EPSD;PhosphoSitePlus	COSMIC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	O43623	SNAI2	P49841	GSK3B	S92	H99Q	99	Missense	distal	7	no	7.260	6.724	EPSD;PhosphoSitePlus	COSMIC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	O43623	SNAI2	P49841	GSK3B	S92	D98N	98	Missense	distal	6	no	7.260	7.261	EPSD;PhosphoSitePlus	COSMIC;GDSC;CCLE	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	O43623	SNAI2	P49841	GSK3B	S96	H99Q	99	Missense	distal	3	no	7.461	7.452	EPSD;PhosphoSitePlus	COSMIC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	O43623	SNAI2	P49841	GSK3B	S96	D98N	98	Missense	proximal	2	no	7.461	6.838	EPSD;PhosphoSitePlus	COSMIC;GDSC;CCLE	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	O43623	SNAI2	P49841	GSK3B	S96	G101D	101	Missense	distal	5	no	7.461	7.525	EPSD;PhosphoSitePlus	COSMIC	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	O43623	SNAI2	P49841	GSK3B	S100	H99Q	99	Missense	proximal	-1	no	7.492	7.437	EPSD;PhosphoSitePlus	COSMIC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	O43623	SNAI2	P49841	GSK3B	S100	D98N	98	Missense	proximal	-2	no	7.492	7.279	EPSD;PhosphoSitePlus	COSMIC;GDSC;CCLE	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	O43623	SNAI2	P49841	GSK3B	S100	G101D	101	Missense	proximal	1	no	7.492	7.583	EPSD;PhosphoSitePlus	COSMIC	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	O43623	SNAI2	P49841	GSK3B	S104	H99Q	99	Missense	distal	-5	no	9.411	9.388	PhosphoSitePlus;EPSD	COSMIC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	O43623	SNAI2	P49841	GSK3B	S104	D98N	98	Missense	distal	-6	no	9.411	9.434	PhosphoSitePlus;EPSD	COSMIC;GDSC;CCLE	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	O43623	SNAI2	P49841	GSK3B	S104	G101D	101	Missense	distal	-3	no	9.411	9.462	PhosphoSitePlus;EPSD	COSMIC	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	O43623	SNAI2	P49841	GSK3B	S247	N245D	245	Missense	proximal	-2	no	6.713	6.926	EPSD	COSMIC	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	O43623	SNAI2	P49841	GSK3B	S247	S251C	251	Missense	distal	4	no	6.713	0.580	EPSD	COSMIC	6.007	Loss
CMGC_GSK_GSK3B_ST	O43623	SNAI2	P49841	GSK3B	S254	L255P	255	Missense	proximal	1	no	3.378	6.238	EPSD	COSMIC	6.007	Gain
CMGC_GSK_GSK3B_ST	P07900	HSP90AA1	P49841	GSK3B	S68	S72T	72	Missense	distal	4	no	6.717	5.848	EPSD	COSMIC	6.007	Loss
CMGC_GSK_GSK3B_ST	P07900	HSP90AA1	P49841	GSK3B	S673	A670V	670	Missense	distal	-3	no	6.462	6.608	EPSD	COSMIC	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	P07900	HSP90AA1	P49841	GSK3B	S677	A670V	670	Missense	distal	-7	no	6.602	6.601	EPSD	COSMIC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	Q9BXF6	RAB11FIP5	P49841	GSK3B	T165	R170H	170	Missense	distal	5	no	7.251	6.262	EPSD	COSMIC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	Q9BXF6	RAB11FIP5	P49841	GSK3B	T165	F168L	168	Missense	distal	3	no	7.251	7.161	EPSD	COSMIC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	Q9BXF6	RAB11FIP5	P49841	GSK3B	T165	T165P	165	Missense	central	0	yes	7.251	0.000	EPSD	COSMIC	6.007	Loss
CMGC_GSK_GSK3B_ST	Q9BXF6	RAB11FIP5	P49841	GSK3B	S188	R187M	187	Missense	proximal	-1	no	6.716	6.803	EPSD;PhosphoSitePlus	COSMIC	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	Q9BXF6	RAB11FIP5	P49841	GSK3B	S188	P189S	189	Missense	proximal	1	no	6.716	2.872	EPSD;PhosphoSitePlus	COSMIC	6.007	Loss
CMGC_GSK_GSK3B_ST	Q9BXF6	RAB11FIP5	P49841	GSK3B	S244	S244Y	244	Missense	central	0	yes	6.773	0.000	EPSD	COSMIC	6.007	Loss
CMGC_GSK_GSK3B_ST	Q9BXF6	RAB11FIP5	P49841	GSK3B	S244	K239N	239	Missense	distal	-5	no	6.773	6.281	EPSD	COSMIC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	Q9BXF6	RAB11FIP5	P49841	GSK3B	T246	S244Y	244	Missense	proximal	-2	no	6.074	5.755	EPSD	COSMIC	6.007	Loss
CMGC_GSK_GSK3B_ST	Q9BXF6	RAB11FIP5	P49841	GSK3B	T246	K239N	239	Missense	distal	-7	no	6.074	6.059	EPSD	COSMIC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	Q9BXF6	RAB11FIP5	P49841	GSK3B	T246	G253S	253	Missense	distal	7	no	6.074	6.054	EPSD	COSMIC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	Q9BXF6	RAB11FIP5	P49841	GSK3B	T250	S244Y	244	Missense	distal	-6	no	6.575	6.489	EPSD	COSMIC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	Q9BXF6	RAB11FIP5	P49841	GSK3B	T250	D255Y	255	Missense	distal	5	no	6.575	5.470	EPSD	COSMIC	6.007	Loss
CMGC_GSK_GSK3B_ST	Q9BXF6	RAB11FIP5	P49841	GSK3B	T250	G253S	253	Missense	distal	3	no	6.575	6.532	EPSD	COSMIC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	Q9BXF6	RAB11FIP5	P49841	GSK3B	S256	D255Y	255	Missense	proximal	-1	no	6.295	6.216	EPSD	COSMIC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	Q9BXF6	RAB11FIP5	P49841	GSK3B	S256	G253S	253	Missense	distal	-3	no	6.295	6.300	EPSD	COSMIC	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	Q9BXF6	RAB11FIP5	P49841	GSK3B	S260	D255Y	255	Missense	distal	-5	no	7.907	8.287	EPSD	COSMIC	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	Q9BXF6	RAB11FIP5	P49841	GSK3B	S260	G253S	253	Missense	distal	-7	no	7.907	7.909	EPSD	COSMIC	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	Q9BXF6	RAB11FIP5	P49841	GSK3B	T276	L275F	275	Missense	proximal	-1	no	6.143	6.088	PhosphoSitePlus;EPSD	COSMIC;GDSC;CCLE	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	Q9BXF6	RAB11FIP5	P49841	GSK3B	T276	R277H	277	Missense	proximal	1	no	6.143	4.763	PhosphoSitePlus;EPSD	COSMIC;GDSC;CCLE	6.007	Loss
CMGC_GSK_GSK3B_ST	Q9BXF6	RAB11FIP5	P49841	GSK3B	T276	A272T	272	Missense	distal	-4	no	6.143	6.967	PhosphoSitePlus;EPSD	COSMIC	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	Q9BXF6	RAB11FIP5	P49841	GSK3B	S278	L275F	275	Missense	distal	-3	no	8.421	8.478	EPSD	COSMIC;GDSC;CCLE	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	Q9BXF6	RAB11FIP5	P49841	GSK3B	S278	R277H	277	Missense	proximal	-1	no	8.421	8.507	EPSD	COSMIC;GDSC;CCLE	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	Q9BXF6	RAB11FIP5	P49841	GSK3B	S278	A272T	272	Missense	distal	-6	no	8.421	8.352	EPSD	COSMIC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	Q9BXF6	RAB11FIP5	P49841	GSK3B	S282	L275F	275	Missense	distal	-7	no	6.182	6.192	EPSD	COSMIC;GDSC;CCLE	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	Q9BXF6	RAB11FIP5	P49841	GSK3B	S282	R277H	277	Missense	distal	-5	no	6.182	5.651	EPSD	COSMIC;GDSC;CCLE	6.007	Loss
CMGC_GSK_GSK3B_ST	Q9BXF6	RAB11FIP5	P49841	GSK3B	S282	G289V	289	Missense	distal	7	no	6.182	6.588	EPSD	COSMIC	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	Q9BXF6	RAB11FIP5	P49841	GSK3B	S283	R277H	277	Missense	distal	-6	no	6.743	6.766	EPSD	COSMIC;GDSC;CCLE	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	Q9BXF6	RAB11FIP5	P49841	GSK3B	S283	G289V	289	Missense	distal	6	no	6.743	6.736	EPSD	COSMIC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	Q9BXF6	RAB11FIP5	P49841	GSK3B	S296	F300L	300	Missense	distal	4	no	5.511	6.407	EPSD	COSMIC	6.007	Gain
CMGC_GSK_GSK3B_ST	Q9BXF6	RAB11FIP5	P49841	GSK3B	T305	A310T	310	Missense	distal	5	no	5.990	6.042	EPSD	COSMIC;GDSC;CCLE	6.007	Gain
CMGC_GSK_GSK3B_ST	Q9BXF6	RAB11FIP5	P49841	GSK3B	S361	S359L	359	Missense	proximal	-2	no	8.012	7.938	EPSD	COSMIC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	Q9BXF6	RAB11FIP5	P49841	GSK3B	S373	R374Q	374	Missense	proximal	1	no	6.129	5.181	EPSD	COSMIC	6.007	Loss
CMGC_GSK_GSK3B_ST	Q9BXF6	RAB11FIP5	P49841	GSK3B	S373	A370T	370	Missense	distal	-3	no	6.129	6.134	EPSD	COSMIC	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	Q9BXF6	RAB11FIP5	P49841	GSK3B	S373	S372F	372	Missense	proximal	-1	no	6.129	5.999	EPSD	COSMIC	6.007	Loss
CMGC_GSK_GSK3B_ST	Q9BXF6	RAB11FIP5	P49841	GSK3B	S373	S373F	373	Missense	central	0	yes	6.129	0.000	EPSD	COSMIC	6.007	Loss
CMGC_GSK_GSK3B_ST	Q9BXF6	RAB11FIP5	P49841	GSK3B	S391	T386N	386	Missense	distal	-5	no	7.035	6.454	EPSD	COSMIC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	Q9BXF6	RAB11FIP5	P49841	GSK3B	S391	D385E	385	Missense	distal	-6	no	7.035	6.999	EPSD	COSMIC;GDSC;CCLE	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	Q9BXF6	RAB11FIP5	P49841	GSK3B	T519	P524L	524	Missense	distal	5	no	6.652	5.371	EPSD	COSMIC	6.007	Loss
CMGC_GSK_GSK3B_ST	Q9BXF6	RAB11FIP5	P49841	GSK3B	T519	P518L	518	Missense	proximal	-1	no	6.652	6.521	EPSD	COSMIC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	Q9BXF6	RAB11FIP5	P49841	GSK3B	T519	H525Y	525	Missense	distal	6	no	6.652	6.656	EPSD	COSMIC	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	Q9BXF6	RAB11FIP5	P49841	GSK3B	S523	P524L	524	Missense	proximal	1	no	6.242	3.381	EPSD	COSMIC	6.007	Loss
CMGC_GSK_GSK3B_ST	Q9BXF6	RAB11FIP5	P49841	GSK3B	S523	P518L	518	Missense	distal	-5	no	6.242	6.508	EPSD	COSMIC	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	Q9BXF6	RAB11FIP5	P49841	GSK3B	S523	H525Y	525	Missense	proximal	2	no	6.242	6.335	EPSD	COSMIC	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	Q9BXF6	RAB11FIP5	P49841	GSK3B	S538	A532T	532	Missense	distal	-6	no	7.258	7.190	EPSD	COSMIC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	Q9BXF6	RAB11FIP5	P49841	GSK3B	S538	G537V	537	Missense	proximal	-1	no	7.258	7.300	EPSD	COSMIC	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	Q9BXF6	RAB11FIP5	P49841	GSK3B	S538	S538N	538	Missense	central	0	yes	7.258	0.000	EPSD	COSMIC	6.007	Loss
CMGC_GSK_GSK3B_ST	Q9BXF6	RAB11FIP5	P49841	GSK3B	S538	R541K	541	Missense	distal	3	no	7.258	7.502	EPSD	COSMIC	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	P08047	SP1	P49841	GSK3B	S59	S59Y	59	Missense	central	0	yes	6.846	0.000	EPSD	COSMIC	6.007	Loss
CMGC_GSK_GSK3B_ST	P08047	SP1	P49841	GSK3B	S69	E72K	72	Missense	distal	3	no	9.099	8.991	EPSD	COSMIC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	P08047	SP1	P49841	GSK3B	S73	E72K	72	Missense	proximal	-1	no	7.500	7.567	EPSD	COSMIC	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	P08047	SP1	P49841	GSK3B	S73	N79K	79	Missense	distal	6	no	7.500	7.501	EPSD	COSMIC	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	P08047	SP1	P49841	GSK3B	S81	Q86R	86	Missense	distal	5	no	6.644	6.983	EPSD	COSMIC	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	P08047	SP1	P49841	GSK3B	S81	N79K	79	Missense	proximal	-2	no	6.644	6.739	EPSD	COSMIC	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	P08047	SP1	P49841	GSK3B	S81	P84L	84	Missense	distal	3	no	6.644	6.326	EPSD	COSMIC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	P08047	SP1	P49841	GSK3B	S698	H700Y	700	Missense	proximal	2	no	6.831	6.924	EPSD	COSMIC	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	P08047	SP1	P49841	GSK3B	S728	G729S	729	Missense	proximal	1	no	6.055	5.404	EPSD;PhosphoSitePlus	COSMIC	6.007	Loss
CMGC_GSK_GSK3B_ST	P08047	SP1	P49841	GSK3B	S728	S728N	728	Missense	central	0	yes	6.055	0.000	EPSD;PhosphoSitePlus	COSMIC	6.007	Loss
CMGC_GSK_GSK3B_ST	P08047	SP1	P49841	GSK3B	S728	A730E	730	Missense	proximal	2	no	6.055	5.960	EPSD;PhosphoSitePlus	COSMIC	6.007	Loss
CMGC_GSK_GSK3B_ST	P08047	SP1	P49841	GSK3B	S728	S732L	732	Missense	distal	4	no	6.055	3.337	EPSD;PhosphoSitePlus	COSMIC	6.007	Loss
CMGC_GSK_GSK3B_ST	P08047	SP1	P49841	GSK3B	S735	T739P	739	Missense	distal	4	no	6.564	4.462	EPSD	COSMIC	6.007	Loss
CMGC_GSK_GSK3B_ST	P08047	SP1	P49841	GSK3B	S735	G729S	729	Missense	distal	-6	no	6.564	6.548	EPSD	COSMIC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	P08047	SP1	P49841	GSK3B	S735	S728N	728	Missense	distal	-7	no	6.564	6.570	EPSD	COSMIC	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	P08047	SP1	P49841	GSK3B	S735	A730E	730	Missense	distal	-5	no	6.564	6.718	EPSD	COSMIC	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	P08047	SP1	P49841	GSK3B	S735	S732L	732	Missense	distal	-3	no	6.564	6.574	EPSD	COSMIC	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	P08047	SP1	P49841	GSK3B	T737	T739P	739	Missense	proximal	2	no	6.983	7.301	EPSD	COSMIC	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	P08047	SP1	P49841	GSK3B	T737	A730E	730	Missense	distal	-7	no	6.983	6.993	EPSD	COSMIC	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	P08047	SP1	P49841	GSK3B	T737	S732L	732	Missense	distal	-5	no	6.983	7.092	EPSD	COSMIC	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	P08047	SP1	P49841	GSK3B	T739	T739P	739	Missense	central	0	yes	7.178	0.000	EPSD	COSMIC	6.007	Loss
CMGC_GSK_GSK3B_ST	P08047	SP1	P49841	GSK3B	T739	T746P	746	Missense	distal	7	no	7.178	7.174	EPSD	COSMIC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	P08047	SP1	P49841	GSK3B	S741	T739P	739	Missense	proximal	-2	no	6.380	6.609	EPSD	COSMIC	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	P08047	SP1	P49841	GSK3B	S741	T746P	746	Missense	distal	5	no	6.380	7.356	EPSD	COSMIC	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	P08047	SP1	P49841	GSK3B	T745	T746P	746	Missense	proximal	1	no	3.789	6.980	EPSD	COSMIC	6.007	Gain
CMGC_GSK_GSK3B_ST	P31749	AKT1	P49841	GSK3B	T92	R86H	86	Missense	distal	-6	no	7.359	7.383	EPSD	COSMIC;GDSC;CCLE	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	P31749	AKT1	P49841	GSK3B	T92	E97K	97	Missense	distal	5	no	7.359	6.492	EPSD	COSMIC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	P31749	AKT1	P49841	GSK3B	T92	E91D	91	Missense	proximal	-1	no	7.359	7.311	EPSD	COSMIC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	P31749	AKT1	P49841	GSK3B	T92	E91K	91	Missense	proximal	-1	no	7.359	7.426	EPSD	COSMIC	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	P31749	AKT1	P49841	GSK3B	T92	W99R	99	Missense	distal	7	no	7.359	7.251	EPSD	COSMIC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	P31749	AKT1	P49841	GSK3B	S122	E115K	115	Missense	distal	-7	no	7.127	7.116	EPSD	COSMIC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	P31749	AKT1	P49841	GSK3B	S122	G123D	123	Missense	proximal	1	no	7.127	7.218	EPSD	COSMIC	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	P31749	AKT1	P49841	GSK3B	S122	D127N	127	Missense	distal	5	no	7.127	6.701	EPSD	COSMIC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	P31749	AKT1	P49841	GSK3B	S122	E116D	116	Missense	distal	-6	no	7.127	7.164	EPSD	COSMIC	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	P31749	AKT1	P49841	GSK3B	S124	G123D	123	Missense	proximal	-1	no	6.748	6.681	EPSD	COSMIC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	P31749	AKT1	P49841	GSK3B	S124	D127N	127	Missense	distal	3	no	6.748	6.701	EPSD	COSMIC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	P31749	AKT1	P49841	GSK3B	S124	G130R	130	Missense	distal	6	no	6.748	6.747	EPSD	COSMIC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	P31749	AKT1	P49841	GSK3B	T312	M306T	306	Missense	distal	-6	no	6.116	6.111	EPSD	COSMIC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	P31749	AKT1	P49841	GSK3B	T312	M306L	306	Missense	distal	-6	no	6.116	6.168	EPSD	COSMIC	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	P31749	AKT1	P49841	GSK3B	T312	M306I	306	Missense	distal	-6	no	6.116	6.106	EPSD	COSMIC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	P31749	AKT1	P49841	GSK3B	T312	T312I	312	Missense	central	0	yes	6.116	0.000	EPSD	COSMIC	6.007	Loss
CMGC_GSK_GSK3B_ST	P31749	AKT1	P49841	GSK3B	S422	V416M	416	Missense	distal	-6	no	7.966	7.980	EPSD	COSMIC	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	P31749	AKT1	P49841	GSK3B	S422	S422R	422	Missense	central	0	yes	7.966	0.000	EPSD	COSMIC	6.007	Loss
CMGC_GSK_GSK3B_ST	P31749	AKT1	P49841	GSK3B	S431	T435I	435	Missense	distal	4	no	6.988	4.535	EPSD	COSMIC	6.007	Loss
CMGC_GSK_GSK3B_ST	P31749	AKT1	P49841	GSK3B	S431	T430M	430	Missense	proximal	-1	no	6.988	7.013	EPSD	COSMIC	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	P31749	AKT1	P49841	GSK3B	T435	T435I	435	Missense	central	0	yes	6.225	0.000	EPSD	COSMIC	6.007	Loss
CMGC_GSK_GSK3B_ST	P31749	AKT1	P49841	GSK3B	T435	T430M	430	Missense	distal	-5	no	6.225	6.238	EPSD	COSMIC	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	P31749	AKT1	P49841	GSK3B	T450	P452L	452	Missense	proximal	2	no	6.970	6.586	EPSD	COSMIC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	P31749	AKT1	P49841	GSK3B	T450	M446I	446	Missense	distal	-4	no	6.970	5.547	EPSD	COSMIC	6.007	Loss
CMGC_GSK_GSK3B_ST	P31749	AKT1	P49841	GSK3B	T450	I447F	447	Missense	distal	-3	no	6.970	6.923	EPSD	COSMIC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	P31749	AKT1	P49841	GSK3B	T450	T443M	443	Missense	distal	-7	no	6.970	6.964	EPSD	COSMIC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	P31749	AKT1	P49841	GSK3B	S473	S477N	477	Missense	distal	4	no	6.180	2.570	PhosphoSitePlus;EPSD	COSMIC	6.007	Loss
CMGC_GSK_GSK3B_ST	P31749	AKT1	P49841	GSK3B	S473	P470L	470	Missense	distal	-3	no	6.180	6.306	PhosphoSitePlus;EPSD	COSMIC	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	P04637	TP53	P49841	GSK3B	S15	F19S	19	Missense	distal	4	no	2.645	6.259	EPSD	COSMIC	6.007	Gain
CMGC_GSK_GSK3B_ST	P04637	TP53	P49841	GSK3B	S33	M40I	40	Missense	distal	7	no	10.252	10.219	EPSD	COSMIC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	P04637	TP53	P49841	GSK3B	S33	V31I	31	Missense	proximal	-2	no	10.252	10.274	EPSD	COSMIC;GDSC;CCLE	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	P04637	TP53	P49841	GSK3B	S33	P36L	36	Missense	distal	3	no	10.252	9.933	EPSD	COSMIC;GDSC;CCLE	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	P04637	TP53	P49841	GSK3B	S33	L35F	35	Missense	proximal	2	no	10.252	9.847	EPSD	COSMIC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	P04637	TP53	P49841	GSK3B	S33	Q38L	38	Missense	distal	5	no	10.252	9.947	EPSD	COSMIC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	P04637	TP53	P49841	GSK3B	S33	S37T	37	Missense	distal	4	no	10.252	9.383	EPSD	COSMIC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	P04637	TP53	P49841	GSK3B	S33	L26P	26	Missense	distal	-7	no	10.252	10.250	EPSD	COSMIC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	P04637	TP53	P49841	GSK3B	S33	P36S	36	Missense	distal	3	no	10.252	10.234	EPSD	COSMIC;GDSC;CCLE	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	P04637	TP53	P49841	GSK3B	S33	A39V	39	Missense	distal	6	no	10.252	10.243	EPSD	COSMIC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	P04637	TP53	P49841	GSK3B	S33	A39S	39	Missense	distal	6	no	10.252	10.253	EPSD	COSMIC	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	P04637	TP53	P49841	GSK3B	S33	N30K	30	Missense	distal	-3	no	10.252	10.370	EPSD	COSMIC	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	P04637	TP53	P49841	GSK3B	S33	A39T	39	Missense	distal	6	no	10.252	10.255	EPSD	COSMIC	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	P04637	TP53	P49841	GSK3B	S33	P27T	27	Missense	distal	-6	no	10.252	10.173	EPSD	COSMIC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	P04637	TP53	P49841	GSK3B	S33	P36R	36	Missense	distal	3	no	10.252	9.863	EPSD	COSMIC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	P04637	TP53	P49841	GSK3B	S33	L35R	35	Missense	proximal	2	no	10.252	10.210	EPSD	COSMIC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	P04637	TP53	P49841	GSK3B	S33	L35H	35	Missense	proximal	2	no	10.252	9.867	EPSD	COSMIC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	P04637	TP53	P49841	GSK3B	S33	L35P	35	Missense	proximal	2	no	10.252	10.636	EPSD	COSMIC	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	P04637	TP53	P49841	GSK3B	S33	L35V	35	Missense	proximal	2	no	10.252	9.923	EPSD	COSMIC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	P04637	TP53	P49841	GSK3B	S37	Q38L	38	Missense	proximal	1	no	5.749	6.157	EPSD	COSMIC	6.007	Gain
CMGC_GSK_GSK3B_ST	P04637	TP53	P49841	GSK3B	S37	L35P	35	Missense	proximal	-2	no	5.749	6.079	EPSD	COSMIC	6.007	Gain
CMGC_GSK_GSK3B_ST	P04637	TP53	P49841	GSK3B	S37	D41E	41	Missense	distal	4	no	5.749	6.152	EPSD	COSMIC	6.007	Gain
CMGC_GSK_GSK3B_ST	P04637	TP53	P49841	GSK3B	S46	M40I	40	Missense	distal	-6	no	6.634	6.624	EPSD	COSMIC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	P04637	TP53	P49841	GSK3B	S46	W53C	53	Missense	distal	7	no	6.634	6.480	EPSD	COSMIC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	P04637	TP53	P49841	GSK3B	S46	W53G	53	Missense	distal	7	no	6.634	6.108	EPSD	COSMIC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	P04637	TP53	P49841	GSK3B	S46	S46F	46	Missense	central	0	yes	6.634	0.000	EPSD	COSMIC	6.007	Loss
CMGC_GSK_GSK3B_ST	P04637	TP53	P49841	GSK3B	S46	D49Y	49	Missense	distal	3	no	6.634	6.117	EPSD	COSMIC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	P04637	TP53	P49841	GSK3B	S46	P47L	47	Missense	proximal	1	no	6.634	3.774	EPSD	COSMIC	6.007	Loss
CMGC_GSK_GSK3B_ST	P04637	TP53	P49841	GSK3B	S46	D49H	49	Missense	distal	3	no	6.634	6.511	EPSD	COSMIC;GDSC;CCLE	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	P04637	TP53	P49841	GSK3B	S46	P47S	47	Missense	proximal	1	no	6.634	2.790	EPSD	COSMIC	6.007	Loss
CMGC_GSK_GSK3B_ST	P04637	TP53	P49841	GSK3B	S46	D41N	41	Missense	distal	-5	no	6.634	6.070	EPSD	COSMIC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	P04637	TP53	P49841	GSK3B	S46	D48H	48	Missense	proximal	2	no	6.634	6.217	EPSD	COSMIC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	P04637	TP53	P49841	GSK3B	S46	D49N	49	Missense	distal	3	no	6.634	6.588	EPSD	COSMIC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	P04637	TP53	P49841	GSK3B	S46	M44I	44	Missense	proximal	-2	no	6.634	6.955	EPSD	COSMIC	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	P04637	TP53	P49841	GSK3B	S46	Q52H	52	Missense	distal	6	no	6.634	6.628	EPSD	COSMIC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	P04637	TP53	P49841	GSK3B	S46	D49V	49	Missense	distal	3	no	6.634	6.332	EPSD	COSMIC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	P04637	TP53	P49841	GSK3B	S46	A39V	39	Missense	distal	-7	no	6.634	6.633	EPSD	COSMIC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	P04637	TP53	P49841	GSK3B	S46	A39S	39	Missense	distal	-7	no	6.634	6.612	EPSD	COSMIC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	P04637	TP53	P49841	GSK3B	S46	D42Y	42	Missense	distal	-4	no	6.634	6.435	EPSD	COSMIC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	P04637	TP53	P49841	GSK3B	S46	M44R	44	Missense	proximal	-2	no	6.634	6.850	EPSD	COSMIC	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	P04637	TP53	P49841	GSK3B	S46	S46P	46	Missense	central	0	yes	6.634	0.000	EPSD	COSMIC	6.007	Loss
CMGC_GSK_GSK3B_ST	P04637	TP53	P49841	GSK3B	S46	M44V	44	Missense	proximal	-2	no	6.634	6.933	EPSD	COSMIC	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	P04637	TP53	P49841	GSK3B	S46	L45P	45	Missense	proximal	-1	no	6.634	6.766	EPSD	COSMIC	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	P04637	TP53	P49841	GSK3B	S46	M44T	44	Missense	proximal	-2	no	6.634	6.993	EPSD	COSMIC	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	P04637	TP53	P49841	GSK3B	S46	A39T	39	Missense	distal	-7	no	6.634	6.639	EPSD	COSMIC	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	P04637	TP53	P49841	GSK3B	S46	L43F	43	Missense	distal	-3	no	6.634	6.692	EPSD	COSMIC	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	P04637	TP53	P49841	GSK3B	S46	D41H	41	Missense	distal	-5	no	6.634	6.529	EPSD	COSMIC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	P04637	TP53	P49841	GSK3B	S46	D49E	49	Missense	distal	3	no	6.634	6.520	EPSD	COSMIC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	P04637	TP53	P49841	GSK3B	S46	D49G	49	Missense	distal	3	no	6.634	6.583	EPSD	COSMIC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	P04637	TP53	P49841	GSK3B	S46	D48A	48	Missense	proximal	2	no	6.634	6.550	EPSD	COSMIC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	P04637	TP53	P49841	GSK3B	S46	D48Y	48	Missense	proximal	2	no	6.634	6.310	EPSD	COSMIC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	P04637	TP53	P49841	GSK3B	S46	D48E	48	Missense	proximal	2	no	6.634	6.455	EPSD	COSMIC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	P04637	TP53	P49841	GSK3B	S46	D49I	49	Missense	distal	3	no	6.634	6.119	EPSD	COSMIC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	P04637	TP53	P49841	GSK3B	S46	D41E	41	Missense	distal	-5	no	6.634	6.793	EPSD	COSMIC	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	P04637	TP53	P49841	GSK3B	T81	P85S	85	Missense	distal	4	no	5.138	8.109	EPSD	COSMIC	6.007	Gain
CMGC_GSK_GSK3B_ST	P04637	TP53	P49841	GSK3B	T81	P85T	85	Missense	distal	4	no	5.138	7.240	EPSD	COSMIC	6.007	Gain
CMGC_GSK_GSK3B_ST	P04637	TP53	P49841	GSK3B	S106	R110S	110	Missense	distal	4	no	3.276	6.313	EPSD	COSMIC	6.007	Gain
CMGC_GSK_GSK3B_ST	P04637	TP53	P49841	GSK3B	T125	A129T	129	Missense	distal	4	no	5.187	6.730	EPSD	COSMIC	6.007	Gain
CMGC_GSK_GSK3B_ST	P04637	TP53	P49841	GSK3B	S127	C124W	124	Missense	distal	-3	no	7.079	7.075	EPSD	COSMIC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	P04637	TP53	P49841	GSK3B	S127	C124F	124	Missense	distal	-3	no	7.079	7.042	EPSD	COSMIC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	P04637	TP53	P49841	GSK3B	S127	C124S	124	Missense	distal	-3	no	7.079	6.976	EPSD	COSMIC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	P04637	TP53	P49841	GSK3B	S127	S127A	127	Missense	central	0	yes	7.079	0.000	EPSD	COSMIC	6.007	Loss
CMGC_GSK_GSK3B_ST	P04637	TP53	P49841	GSK3B	S127	S127L	127	Missense	central	0	yes	7.079	0.000	EPSD	COSMIC	6.007	Loss
CMGC_GSK_GSK3B_ST	P04637	TP53	P49841	GSK3B	S127	C124T	124	Missense	distal	-3	no	7.079	7.000	EPSD	COSMIC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	P04637	TP53	P49841	GSK3B	S127	S127I	127	Missense	central	0	yes	7.079	0.000	EPSD	COSMIC	6.007	Loss
CMGC_GSK_GSK3B_ST	P04637	TP53	P49841	GSK3B	S127	S127G	127	Missense	central	0	yes	7.079	0.000	EPSD	COSMIC	6.007	Loss
CMGC_GSK_GSK3B_ST	P04637	TP53	P49841	GSK3B	S127	N131H	131	Missense	distal	4	no	7.079	6.933	EPSD	COSMIC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	P04637	TP53	P49841	GSK3B	S127	N131D	131	Missense	distal	4	no	7.079	8.266	EPSD	COSMIC	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	P04637	TP53	P49841	GSK3B	S127	T125I	125	Missense	proximal	-2	no	7.079	7.041	EPSD	COSMIC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	P04637	TP53	P49841	GSK3B	S127	F134I	134	Missense	distal	7	no	7.079	7.337	EPSD	COSMIC	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	P04637	TP53	P49841	GSK3B	S127	K120T	120	Missense	distal	-7	no	7.079	7.085	EPSD	COSMIC	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	P04637	TP53	P49841	GSK3B	S127	F134S	134	Missense	distal	7	no	7.079	7.002	EPSD	COSMIC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	P04637	TP53	P49841	GSK3B	S127	T125K	125	Missense	proximal	-2	no	7.079	6.918	EPSD	COSMIC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	P04637	TP53	P49841	GSK3B	S127	M133I	133	Missense	distal	6	no	7.079	7.084	EPSD	COSMIC	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	P04637	TP53	P49841	GSK3B	S127	N131K	131	Missense	distal	4	no	7.079	7.487	EPSD	COSMIC;CCLE	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	P04637	TP53	P49841	GSK3B	S127	P128S	128	Missense	proximal	1	no	7.079	3.234	EPSD	COSMIC	6.007	Loss
CMGC_GSK_GSK3B_ST	P04637	TP53	P49841	GSK3B	S127	M133L	133	Missense	distal	6	no	7.079	7.080	EPSD	COSMIC	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	P04637	TP53	P49841	GSK3B	S127	A129T	129	Missense	proximal	2	no	7.079	7.198	EPSD	COSMIC	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	P04637	TP53	P49841	GSK3B	S127	T123I	123	Missense	distal	-4	no	7.079	4.932	EPSD	COSMIC	6.007	Loss
CMGC_GSK_GSK3B_ST	P04637	TP53	P49841	GSK3B	S127	A129G	129	Missense	proximal	2	no	7.079	6.813	EPSD	COSMIC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	P04637	TP53	P49841	GSK3B	S127	K132W	132	Missense	distal	5	no	7.079	6.652	EPSD	COSMIC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	P04637	TP53	P49841	GSK3B	S127	A129V	129	Missense	proximal	2	no	7.079	6.802	EPSD	COSMIC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	P04637	TP53	P49841	GSK3B	S127	P128A	128	Missense	proximal	1	no	7.079	3.347	EPSD	COSMIC	6.007	Loss
CMGC_GSK_GSK3B_ST	P04637	TP53	P49841	GSK3B	S127	L130I	130	Missense	distal	3	no	7.079	6.959	EPSD	COSMIC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	P04637	TP53	P49841	GSK3B	S127	S121F	121	Missense	distal	-6	no	7.079	7.026	EPSD	COSMIC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	P04637	TP53	P49841	GSK3B	S127	A129D	129	Missense	proximal	2	no	7.079	7.163	EPSD	COSMIC	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	P04637	TP53	P49841	GSK3B	S127	K120Q	120	Missense	distal	-7	no	7.079	7.073	EPSD	COSMIC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	P04637	TP53	P49841	GSK3B	S127	T125S	125	Missense	proximal	-2	no	7.079	7.052	EPSD	COSMIC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	P04637	TP53	P49841	GSK3B	S127	P128L	128	Missense	proximal	1	no	7.079	4.219	EPSD	COSMIC	6.007	Loss
CMGC_GSK_GSK3B_ST	P04637	TP53	P49841	GSK3B	S127	V122L	122	Missense	distal	-5	no	7.079	6.608	EPSD	COSMIC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	P04637	TP53	P49841	GSK3B	S127	C124L	124	Missense	distal	-3	no	7.079	6.985	EPSD	COSMIC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	P04637	TP53	P49841	GSK3B	S127	N131T	131	Missense	distal	4	no	7.079	9.821	EPSD	COSMIC	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	P04637	TP53	P49841	GSK3B	S127	M133V	133	Missense	distal	6	no	7.079	7.074	EPSD	COSMIC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	P04637	TP53	P49841	GSK3B	S149	P153T	153	Missense	distal	4	no	4.363	6.465	EPSD	COSMIC	6.007	Gain
CMGC_GSK_GSK3B_ST	P04637	TP53	P49841	GSK3B	S149	P153S	153	Missense	distal	4	no	4.363	7.334	EPSD	COSMIC	6.007	Gain
CMGC_GSK_GSK3B_ST	P04637	TP53	P49841	GSK3B	T155	A159S	159	Missense	distal	4	no	4.832	7.243	EPSD	COSMIC	6.007	Gain
CMGC_GSK_GSK3B_ST	P04637	TP53	P49841	GSK3B	T155	A159T	159	Missense	distal	4	no	4.832	6.374	EPSD	COSMIC	6.007	Gain
CMGC_GSK_GSK3B_ST	P04637	TP53	P49841	GSK3B	S183	G187V	187	Missense	distal	4	no	5.252	6.105	EPSD	COSMIC	6.007	Gain
CMGC_GSK_GSK3B_ST	P04637	TP53	P49841	GSK3B	S183	G187D	187	Missense	distal	4	no	5.252	6.071	EPSD	COSMIC	6.007	Gain
CMGC_GSK_GSK3B_ST	P04637	TP53	P49841	GSK3B	S183	G187A	187	Missense	distal	4	no	5.252	6.083	EPSD	COSMIC	6.007	Gain
CMGC_GSK_GSK3B_ST	P04637	TP53	P49841	GSK3B	T211	F212L	212	Missense	proximal	1	no	5.404	6.774	EPSD	COSMIC	6.007	Gain
CMGC_GSK_GSK3B_ST	P04637	TP53	P49841	GSK3B	T211	F212Y	212	Missense	proximal	1	no	5.404	6.317	EPSD	COSMIC	6.007	Gain
CMGC_GSK_GSK3B_ST	P04637	TP53	P49841	GSK3B	S215	P219S	219	Missense	distal	4	no	3.224	6.195	EPSD	COSMIC	6.007	Gain
CMGC_GSK_GSK3B_ST	P04637	TP53	P49841	GSK3B	S315	N310T	310	Missense	distal	-5	no	5.875	6.456	EPSD	COSMIC	6.007	Gain
CMGC_GSK_GSK3B_ST	P04637	TP53	P49841	GSK3B	S315	K319E	319	Missense	distal	4	no	5.875	7.057	EPSD	COSMIC	6.007	Gain
CMGC_GSK_GSK3B_ST	P04637	TP53	P49841	GSK3B	S315	K320N	320	Missense	distal	5	no	5.875	6.113	EPSD	COSMIC;GDSC;CCLE	6.007	Gain
CMGC_GSK_GSK3B_ST	P04637	TP53	P49841	GSK3B	S315	N310L	310	Missense	distal	-5	no	5.875	6.276	EPSD	COSMIC	6.007	Gain
CMGC_GSK_GSK3B_ST	P04637	TP53	P49841	GSK3B	S315	N311Y	311	Missense	distal	-4	no	5.875	6.372	EPSD	COSMIC	6.007	Gain
CMGC_GSK_GSK3B_ST	P04637	TP53	P49841	GSK3B	S315	P322R	322	Missense	distal	7	no	5.875	6.376	EPSD	COSMIC	6.007	Gain
CMGC_GSK_GSK3B_ST	P04637	TP53	P49841	GSK3B	S315	N311K	311	Missense	distal	-4	no	5.875	6.308	EPSD	COSMIC	6.007	Gain
CMGC_GSK_GSK3B_ST	P04637	TP53	P49841	GSK3B	S315	N310H	310	Missense	distal	-5	no	5.875	6.334	EPSD	COSMIC	6.007	Gain
CMGC_GSK_GSK3B_ST	P04637	TP53	P49841	GSK3B	S315	N311H	311	Missense	distal	-4	no	5.875	6.085	EPSD	COSMIC	6.007	Gain
CMGC_GSK_GSK3B_ST	P04637	TP53	P49841	GSK3B	S315	K319R	319	Missense	distal	4	no	5.875	6.039	EPSD	COSMIC	6.007	Gain
CMGC_GSK_GSK3B_ST	P04637	TP53	P49841	GSK3B	S315	N310D	310	Missense	distal	-5	no	5.875	6.439	EPSD	COSMIC	6.007	Gain
CMGC_GSK_GSK3B_ST	P04637	TP53	P49841	GSK3B	S315	N311D	311	Missense	distal	-4	no	5.875	6.572	EPSD	COSMIC	6.007	Gain
CMGC_GSK_GSK3B_ST	P04637	TP53	P49841	GSK3B	S315	Q317P	317	Missense	proximal	2	no	5.875	6.096	EPSD	COSMIC	6.007	Gain
CMGC_GSK_GSK3B_ST	P04637	TP53	P49841	GSK3B	S362	S367F	367	Missense	distal	5	no	7.606	6.939	EPSD	COSMIC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	P04637	TP53	P49841	GSK3B	S362	G361E	361	Missense	proximal	-1	no	7.606	7.587	EPSD	COSMIC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	P04637	TP53	P49841	GSK3B	S362	E358V	358	Missense	distal	-4	no	7.606	6.969	EPSD	COSMIC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	P04637	TP53	P49841	GSK3B	S362	P359S	359	Missense	distal	-3	no	7.606	7.722	EPSD	COSMIC	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	P04637	TP53	P49841	GSK3B	S362	A364D	364	Missense	proximal	2	no	7.606	7.690	EPSD	COSMIC	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	P04637	TP53	P49841	GSK3B	S362	H365Y	365	Missense	distal	3	no	7.606	7.212	EPSD	COSMIC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	P04637	TP53	P49841	GSK3B	S362	G360A	360	Missense	proximal	-2	no	7.606	7.389	EPSD	COSMIC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	P04637	TP53	P49841	GSK3B	S362	A364T	364	Missense	proximal	2	no	7.606	7.724	EPSD	COSMIC	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	P04637	TP53	P49841	GSK3B	S362	G356W	356	Missense	distal	-6	no	7.606	7.560	EPSD	COSMIC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	P04637	TP53	P49841	GSK3B	S362	S366A	366	Missense	distal	4	no	7.606	5.194	EPSD	COSMIC	6.007	Loss
CMGC_GSK_GSK3B_ST	P04637	TP53	P49841	GSK3B	S362	E358Q	358	Missense	distal	-4	no	7.606	7.373	EPSD	COSMIC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	P04637	TP53	P49841	GSK3B	S362	G361R	361	Missense	proximal	-1	no	7.606	7.462	EPSD	COSMIC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	P04637	TP53	P49841	GSK3B	S362	E358K	358	Missense	distal	-4	no	7.606	7.338	EPSD	COSMIC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	P04637	TP53	P49841	GSK3B	S378	R379P	379	Missense	proximal	1	no	4.438	6.758	EPSD	COSMIC	6.007	Gain
CMGC_GSK_GSK3B_ST	Q14896	MYBPC3	P49841	GSK3B	T167	D163N	163	Missense	distal	-4	no	7.883	7.186	EPSD	COSMIC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	Q14896	MYBPC3	P49841	GSK3B	T167	V166M	166	Missense	proximal	-1	no	7.883	7.784	EPSD	COSMIC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	Q14896	MYBPC3	P49841	GSK3B	T167	R160Q	160	Missense	distal	-7	no	7.883	7.879	EPSD	COSMIC;CCLE	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	Q14896	MYBPC3	P49841	GSK3B	S171	V166M	166	Missense	distal	-5	no	6.348	6.070	EPSD	COSMIC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	Q14896	MYBPC3	P49841	GSK3B	S304	F305L	305	Missense	proximal	1	no	4.647	6.017	PhosphoSitePlus;EPSD	COSMIC	6.007	Gain
CMGC_GSK_GSK3B_ST	Q14896	MYBPC3	P49841	GSK3B	T307	R306W	306	Missense	proximal	-1	no	10.058	10.169	EPSD	COSMIC	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	Q14896	MYBPC3	P49841	GSK3B	T307	S311L	311	Missense	distal	4	no	10.058	7.340	EPSD	COSMIC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	Q14896	MYBPC3	P49841	GSK3B	T307	D303Y	303	Missense	distal	-4	no	10.058	9.858	EPSD	COSMIC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	Q14896	MYBPC3	P49841	GSK3B	T307	F305L	305	Missense	proximal	-2	no	10.058	10.314	EPSD	COSMIC	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	Q14896	MYBPC3	P49841	GSK3B	S311	P316S	316	Missense	distal	5	no	6.760	5.806	EPSD	COSMIC;GDSC;CCLE	6.007	Loss
CMGC_GSK_GSK3B_ST	Q14896	MYBPC3	P49841	GSK3B	S311	R306W	306	Missense	distal	-5	no	6.760	6.503	EPSD	COSMIC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	Q14896	MYBPC3	P49841	GSK3B	S311	S311L	311	Missense	central	0	yes	6.760	0.000	EPSD	COSMIC	6.007	Loss
CMGC_GSK_GSK3B_ST	Q14896	MYBPC3	P49841	GSK3B	S311	F305L	305	Missense	distal	-6	no	6.760	6.812	EPSD	COSMIC	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	Q14896	MYBPC3	P49841	GSK3B	T607	Y614D	614	Missense	distal	7	no	7.615	7.227	EPSD	COSMIC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	Q14896	MYBPC3	P49841	GSK3B	S1067	P1069S	1069	Missense	proximal	2	no	9.012	8.568	EPSD	COSMIC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	Q01094	E2F1	P49841	GSK3B	S121	H114Y	114	Missense	distal	-7	no	6.711	6.721	EPSD	COSMIC	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	Q01094	E2F1	P49841	GSK3B	S121	R127L	127	Missense	distal	6	no	6.711	6.710	EPSD	COSMIC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	Q01094	E2F1	P49841	GSK3B	S121	G116V	116	Missense	distal	-5	no	6.711	6.824	EPSD	COSMIC	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	Q01094	E2F1	P49841	GSK3B	S131	R127L	127	Missense	distal	-4	no	6.065	5.902	EPSD	COSMIC	6.007	Loss
CMGC_GSK_GSK3B_ST	Q01094	E2F1	P49841	GSK3B	S307	P312L	312	Missense	distal	5	no	8.116	6.836	EPSD	COSMIC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	Q01094	E2F1	P49841	GSK3B	T311	S318F	318	Missense	distal	7	no	7.138	7.216	EPSD	COSMIC	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	Q01094	E2F1	P49841	GSK3B	T311	P312L	312	Missense	proximal	1	no	7.138	4.278	EPSD	COSMIC	6.007	Loss
CMGC_GSK_GSK3B_ST	Q01094	E2F1	P49841	GSK3B	S313	S318F	318	Missense	distal	5	no	6.819	6.152	EPSD	COSMIC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	Q01094	E2F1	P49841	GSK3B	S313	P312L	312	Missense	proximal	-1	no	6.819	6.688	EPSD	COSMIC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	Q01094	E2F1	P49841	GSK3B	S332	S336L	336	Missense	distal	4	no	8.586	5.868	EPSD	COSMIC	6.007	Loss
CMGC_GSK_GSK3B_ST	Q01094	E2F1	P49841	GSK3B	S332	I330T	330	Missense	proximal	-2	no	8.586	8.623	EPSD	COSMIC	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	Q01094	E2F1	P49841	GSK3B	S332	P335Q	335	Missense	distal	3	no	8.586	8.530	EPSD	COSMIC;GDSC;CCLE	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	Q01094	E2F1	P49841	GSK3B	S332	P335S	335	Missense	distal	3	no	8.586	8.568	EPSD	COSMIC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	Q01094	E2F1	P49841	GSK3B	S332	P334L	334	Missense	proximal	2	no	8.586	8.201	EPSD	COSMIC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	Q01094	E2F1	P49841	GSK3B	S336	S341F	341	Missense	distal	5	no	7.256	6.589	EPSD	COSMIC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	Q01094	E2F1	P49841	GSK3B	S336	S336L	336	Missense	central	0	yes	7.256	0.000	EPSD	COSMIC	6.007	Loss
CMGC_GSK_GSK3B_ST	Q01094	E2F1	P49841	GSK3B	S336	I330T	330	Missense	distal	-6	no	7.256	7.261	EPSD	COSMIC	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	Q01094	E2F1	P49841	GSK3B	S336	P335Q	335	Missense	proximal	-1	no	7.256	7.093	EPSD	COSMIC;GDSC;CCLE	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	Q01094	E2F1	P49841	GSK3B	S336	P335S	335	Missense	proximal	-1	no	7.256	7.200	EPSD	COSMIC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	Q01094	E2F1	P49841	GSK3B	S336	P334L	334	Missense	proximal	-2	no	7.256	6.925	EPSD	COSMIC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	Q01094	E2F1	P49841	GSK3B	S337	S341F	341	Missense	distal	4	no	9.727	6.113	EPSD	COSMIC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	Q01094	E2F1	P49841	GSK3B	S337	S336L	336	Missense	proximal	-1	no	9.727	9.652	EPSD	COSMIC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	Q01094	E2F1	P49841	GSK3B	S337	I330T	330	Missense	distal	-7	no	9.727	9.726	EPSD	COSMIC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	Q01094	E2F1	P49841	GSK3B	S337	P335Q	335	Missense	proximal	-2	no	9.727	9.426	EPSD	COSMIC;GDSC;CCLE	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	Q01094	E2F1	P49841	GSK3B	S337	P335S	335	Missense	proximal	-2	no	9.727	9.471	EPSD	COSMIC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	Q01094	E2F1	P49841	GSK3B	S337	P334L	334	Missense	distal	-3	no	9.727	9.853	EPSD	COSMIC	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	Q01094	E2F1	P49841	GSK3B	T343	L350V	350	Missense	distal	7	no	5.589	6.029	EPSD	COSMIC	6.007	Gain
CMGC_GSK_GSK3B_ST	Q01094	E2F1	P49841	GSK3B	S352	P346S	346	Missense	distal	-6	no	6.413	6.392	EPSD	COSMIC;GDSC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	Q01094	E2F1	P49841	GSK3B	S352	L350V	350	Missense	proximal	-2	no	6.413	6.455	EPSD	COSMIC	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	Q01094	E2F1	P49841	GSK3B	S375	S382L	382	Missense	distal	7	no	6.762	6.748	EPSD	COSMIC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	Q01094	E2F1	P49841	GSK3B	S403	P404S	404	Missense	proximal	1	no	9.524	5.679	EPSD;PhosphoSitePlus	COSMIC	6.007	Loss
CMGC_GSK_GSK3B_ST	Q15746	MYLK	P49841	GSK3B	S18	S16C	16	Missense	proximal	-2	no	8.033	7.721	EPSD	COSMIC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	Q15746	MYLK	P49841	GSK3B	S18	R23I	23	Missense	distal	5	no	8.033	7.050	EPSD	COSMIC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	Q15746	MYLK	P49841	GSK3B	S18	P21L	21	Missense	distal	3	no	8.033	7.714	EPSD	COSMIC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	Q15746	MYLK	P49841	GSK3B	S18	S13F	13	Missense	distal	-5	no	8.033	8.592	EPSD	COSMIC;CCLE	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	Q15746	MYLK	P49841	GSK3B	S283	K281R	281	Missense	proximal	-2	no	5.997	6.016	EPSD	COSMIC	6.007	Gain
CMGC_GSK_GSK3B_ST	Q15746	MYLK	P49841	GSK3B	S283	S280L	280	Missense	distal	-3	no	5.997	6.007	EPSD	COSMIC	6.007	Gain
CMGC_GSK_GSK3B_ST	Q15746	MYLK	P49841	GSK3B	S305	G303C	303	Missense	proximal	-2	no	6.725	6.531	EPSD	COSMIC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	Q15746	MYLK	P49841	GSK3B	S305	S312N	312	Missense	distal	7	no	6.725	6.848	EPSD	COSMIC	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	Q15746	MYLK	P49841	GSK3B	S305	S298Y	298	Missense	distal	-7	no	6.725	6.753	EPSD	COSMIC	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	Q15746	MYLK	P49841	GSK3B	S320	D327N	327	Missense	distal	7	no	6.300	6.368	EPSD	COSMIC	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	Q15746	MYLK	P49841	GSK3B	S320	E323K	323	Missense	distal	3	no	6.300	6.193	EPSD	COSMIC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	Q15746	MYLK	P49841	GSK3B	S324	D327N	327	Missense	distal	3	no	6.466	6.420	EPSD	COSMIC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	Q15746	MYLK	P49841	GSK3B	S324	E323K	323	Missense	proximal	-1	no	6.466	6.533	EPSD	COSMIC	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	Q15746	MYLK	P49841	GSK3B	S328	D327N	327	Missense	proximal	-1	no	9.091	9.213	EPSD	COSMIC	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	Q15746	MYLK	P49841	GSK3B	S328	E323K	323	Missense	distal	-5	no	9.091	8.860	EPSD	COSMIC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	Q15746	MYLK	P49841	GSK3B	S365	P359L	359	Missense	distal	-6	no	8.153	8.131	EPSD	COSMIC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	Q15746	MYLK	P49841	GSK3B	S947	Q949R	949	Missense	proximal	2	no	7.383	7.178	EPSD	COSMIC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	Q15746	MYLK	P49841	GSK3B	S947	E940K	940	Missense	distal	-7	no	7.383	7.372	EPSD	COSMIC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	Q15746	MYLK	P49841	GSK3B	S947	P948S	948	Missense	proximal	1	no	7.383	3.538	EPSD	COSMIC;GDSC;CCLE	6.007	Loss
CMGC_GSK_GSK3B_ST	Q15746	MYLK	P49841	GSK3B	S947	S947N	947	Missense	central	0	yes	7.383	0.000	EPSD	COSMIC	6.007	Loss
CMGC_GSK_GSK3B_ST	Q15746	MYLK	P49841	GSK3B	S1093	A1099T	1099	Missense	distal	6	no	6.013	6.017	EPSD	COSMIC	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	Q15746	MYLK	P49841	GSK3B	S1093	G1095R	1095	Missense	proximal	2	no	6.013	6.290	EPSD	COSMIC	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	Q15746	MYLK	P49841	GSK3B	S1093	S1091L	1091	Missense	proximal	-2	no	6.013	5.939	EPSD	COSMIC	6.007	Loss
CMGC_GSK_GSK3B_ST	Q15746	MYLK	P49841	GSK3B	S1093	T1096A	1096	Missense	distal	3	no	6.013	5.709	EPSD	COSMIC	6.007	Loss
CMGC_GSK_GSK3B_ST	Q15746	MYLK	P49841	GSK3B	T1230	P1232L	1232	Missense	proximal	2	no	7.083	6.699	EPSD	COSMIC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	Q15746	MYLK	P49841	GSK3B	T1337	I1343T	1343	Missense	distal	6	no	10.713	10.715	EPSD	COSMIC	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	Q15746	MYLK	P49841	GSK3B	T1337	P1338S	1338	Missense	proximal	1	no	10.713	6.868	EPSD	COSMIC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	Q15746	MYLK	P49841	GSK3B	S1419	T1412A	1412	Missense	distal	-7	no	6.665	6.661	EPSD	COSMIC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	Q15746	MYLK	P49841	GSK3B	S1419	V1424I	1424	Missense	distal	5	no	6.665	6.500	EPSD	COSMIC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	Q15746	MYLK	P49841	GSK3B	S1659	D1666N	1666	Missense	distal	7	no	8.263	8.331	EPSD	COSMIC	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	Q15746	MYLK	P49841	GSK3B	S1772	P1777S	1777	Missense	distal	5	no	8.059	7.105	EPSD	COSMIC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	Q15746	MYLK	P49841	GSK3B	S1773	P1777S	1777	Missense	distal	4	no	4.589	7.560	EPSD	COSMIC	6.007	Gain
CMGC_GSK_GSK3B_ST	Q15746	MYLK	P49841	GSK3B	T1774	L1781F	1781	Missense	distal	7	no	5.949	6.041	EPSD	COSMIC	6.007	Gain
CMGC_GSK_GSK3B_ST	Q15746	MYLK	P49841	GSK3B	S1776	P1777S	1777	Missense	proximal	1	no	8.990	5.145	PhosphoSitePlus	COSMIC	6.007	Loss
CMGC_GSK_GSK3B_ST	Q15746	MYLK	P49841	GSK3B	S1776	L1781F	1781	Missense	distal	5	no	8.990	8.649	PhosphoSitePlus	COSMIC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	Q15746	MYLK	P49841	GSK3B	S1779	P1777S	1777	Missense	proximal	-2	no	8.264	8.008	EPSD	COSMIC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	Q15746	MYLK	P49841	GSK3B	S1779	L1781F	1781	Missense	proximal	2	no	8.264	7.859	EPSD	COSMIC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	Q15746	MYLK	P49841	GSK3B	S1848	D1846Y	1846	Missense	proximal	-2	no	6.677	6.374	EPSD	COSMIC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	Q15746	MYLK	P49841	GSK3B	S1848	R1850S	1850	Missense	proximal	2	no	6.677	6.659	EPSD	COSMIC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	P20393	NR1D1	P49841	GSK3B	S19	S23P	23	Missense	distal	4	no	8.683	5.712	EPSD	COSMIC	6.007	Loss
CMGC_GSK_GSK3B_ST	P20393	NR1D1	P49841	GSK3B	S19	R26C	26	Missense	distal	7	no	8.683	8.638	EPSD	COSMIC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	P20393	NR1D1	P49841	GSK3B	S22	S23P	23	Missense	proximal	1	no	4.444	8.289	EPSD	COSMIC	6.007	Gain
CMGC_GSK_GSK3B_ST	P20393	NR1D1	P49841	GSK3B	S23	S23P	23	Missense	central	0	yes	9.588	0.000	EPSD	COSMIC	6.007	Loss
CMGC_GSK_GSK3B_ST	P20393	NR1D1	P49841	GSK3B	S23	R26C	26	Missense	distal	3	no	9.588	9.744	EPSD	COSMIC	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	P20393	NR1D1	P49841	GSK3B	S59	A65D	65	Missense	distal	6	no	6.607	6.602	EPSD;PhosphoSitePlus	COSMIC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	P20393	NR1D1	P49841	GSK3B	S59	D63A	63	Missense	distal	4	no	6.607	6.619	EPSD;PhosphoSitePlus	COSMIC	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	P20393	NR1D1	P49841	GSK3B	S84	P81L	81	Missense	distal	-3	no	7.876	8.003	EPSD	COSMIC	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	P20393	NR1D1	P49841	GSK3B	S84	P81S	81	Missense	distal	-3	no	7.876	7.993	EPSD	COSMIC	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	P20393	NR1D1	P49841	GSK3B	S85	P81S	81	Missense	distal	-4	no	5.493	6.057	EPSD	COSMIC	6.007	Gain
CMGC_GSK_GSK3B_ST	P20393	NR1D1	P49841	GSK3B	S86	S93F	93	Missense	distal	7	no	6.187	6.265	EPSD	COSMIC;GDSC;CCLE	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	P20393	NR1D1	P49841	GSK3B	S86	P81L	81	Missense	distal	-5	no	6.187	6.453	EPSD	COSMIC	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	P20393	NR1D1	P49841	GSK3B	S86	P81S	81	Missense	distal	-5	no	6.187	6.344	EPSD	COSMIC	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	P20393	NR1D1	P49841	GSK3B	S87	S93F	93	Missense	distal	6	no	7.104	7.092	EPSD	COSMIC;GDSC;CCLE	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	P20393	NR1D1	P49841	GSK3B	S87	P81L	81	Missense	distal	-6	no	7.104	7.082	EPSD	COSMIC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	P20393	NR1D1	P49841	GSK3B	S87	P81S	81	Missense	distal	-6	no	7.104	7.084	EPSD	COSMIC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	P20393	NR1D1	P49841	GSK3B	S309	N313S	313	Missense	distal	4	no	3.014	6.624	EPSD	COSMIC	6.007	Gain
CMGC_GSK_GSK3B_ST	P20393	NR1D1	P49841	GSK3B	S322	H318R	318	Missense	distal	-4	no	9.126	9.027	EPSD	COSMIC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	Q9UKT5	FBXO4	P49841	GSK3B	S57	T58P	58	Missense	proximal	1	no	3.988	7.179	EPSD	COSMIC	6.007	Gain
CMGC_GSK_GSK3B_ST	Q9NYF8	BCLAF1	P49841	GSK3B	S6	G2S	2	Missense	distal	-4	no	7.649	8.078	EPSD	COSMIC	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	Q9NYF8	BCLAF1	P49841	GSK3B	S6	S11P	11	Missense	distal	5	no	7.649	8.603	EPSD	COSMIC	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	Q9NYF8	BCLAF1	P49841	GSK3B	S6	N5S	5	Missense	proximal	-1	no	7.649	7.588	EPSD	COSMIC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	Q9NYF8	BCLAF1	P49841	GSK3B	S6	S11L	11	Missense	distal	5	no	7.649	7.323	EPSD	COSMIC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	Q9NYF8	BCLAF1	P49841	GSK3B	S10	S11P	11	Missense	proximal	1	no	2.558	6.403	EPSD	COSMIC	6.007	Gain
CMGC_GSK_GSK3B_ST	Q9NYF8	BCLAF1	P49841	GSK3B	S15	S11P	11	Missense	distal	-4	no	7.933	7.370	EPSD	COSMIC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	Q9NYF8	BCLAF1	P49841	GSK3B	S15	S11L	11	Missense	distal	-4	no	7.933	6.583	EPSD	COSMIC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	Q9NYF8	BCLAF1	P49841	GSK3B	S15	R16T	16	Missense	proximal	1	no	7.933	7.062	EPSD	COSMIC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	Q9NYF8	BCLAF1	P49841	GSK3B	S19	R16T	16	Missense	distal	-3	no	7.212	7.068	EPSD	COSMIC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	Q9NYF8	BCLAF1	P49841	GSK3B	S36	R37H	37	Missense	proximal	1	no	8.864	7.484	EPSD	COSMIC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	Q9NYF8	BCLAF1	P49841	GSK3B	S36	S36F	36	Missense	central	0	yes	8.864	0.000	EPSD	COSMIC	6.007	Loss
CMGC_GSK_GSK3B_ST	Q9NYF8	BCLAF1	P49841	GSK3B	S36	S36Y	36	Missense	central	0	yes	8.864	0.000	EPSD	COSMIC	6.007	Loss
CMGC_GSK_GSK3B_ST	Q9NYF8	BCLAF1	P49841	GSK3B	S36	R37T	37	Missense	proximal	1	no	8.864	7.993	EPSD	COSMIC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	Q9NYF8	BCLAF1	P49841	GSK3B	S36	R37K	37	Missense	proximal	1	no	8.864	7.638	EPSD	COSMIC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	Q9NYF8	BCLAF1	P49841	GSK3B	S36	S38F	38	Missense	proximal	2	no	8.864	8.519	EPSD	COSMIC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	Q9NYF8	BCLAF1	P49841	GSK3B	S36	R39H	39	Missense	distal	3	no	8.864	9.207	EPSD	COSMIC	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	Q9NYF8	BCLAF1	P49841	GSK3B	S36	R37S	37	Missense	proximal	1	no	8.864	7.339	EPSD	COSMIC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	Q9NYF8	BCLAF1	P49841	GSK3B	S38	R37H	37	Missense	proximal	-1	no	6.594	6.679	EPSD	COSMIC	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	Q9NYF8	BCLAF1	P49841	GSK3B	S38	S36F	36	Missense	proximal	-2	no	6.594	6.263	EPSD	COSMIC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	Q9NYF8	BCLAF1	P49841	GSK3B	S38	R45P	45	Missense	distal	7	no	6.594	6.092	EPSD	COSMIC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	Q9NYF8	BCLAF1	P49841	GSK3B	S38	R45M	45	Missense	distal	7	no	6.594	6.524	EPSD	COSMIC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	Q9NYF8	BCLAF1	P49841	GSK3B	S38	S36Y	36	Missense	proximal	-2	no	6.594	6.274	EPSD	COSMIC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	Q9NYF8	BCLAF1	P49841	GSK3B	S38	R37T	37	Missense	proximal	-1	no	6.594	6.656	EPSD	COSMIC	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	Q9NYF8	BCLAF1	P49841	GSK3B	S38	R37K	37	Missense	proximal	-1	no	6.594	6.786	EPSD	COSMIC	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	Q9NYF8	BCLAF1	P49841	GSK3B	S38	S38F	38	Missense	central	0	yes	6.594	0.000	EPSD	COSMIC	6.007	Loss
CMGC_GSK_GSK3B_ST	Q9NYF8	BCLAF1	P49841	GSK3B	S38	R39H	39	Missense	proximal	1	no	6.594	5.213	EPSD	COSMIC	6.007	Loss
CMGC_GSK_GSK3B_ST	Q9NYF8	BCLAF1	P49841	GSK3B	S38	S36T	36	Missense	proximal	-2	no	6.594	6.621	EPSD	COSMIC	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	Q9NYF8	BCLAF1	P49841	GSK3B	S38	R37S	37	Missense	proximal	-1	no	6.594	6.731	EPSD	COSMIC	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	Q9NYF8	BCLAF1	P49841	GSK3B	S40	R37H	37	Missense	distal	-3	no	9.026	8.969	EPSD	COSMIC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	Q9NYF8	BCLAF1	P49841	GSK3B	S40	S36F	36	Missense	distal	-4	no	9.026	7.872	EPSD	COSMIC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	Q9NYF8	BCLAF1	P49841	GSK3B	S40	R45P	45	Missense	distal	5	no	9.026	9.664	EPSD	COSMIC	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	Q9NYF8	BCLAF1	P49841	GSK3B	S40	R47T	47	Missense	distal	7	no	9.026	8.529	EPSD	COSMIC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	Q9NYF8	BCLAF1	P49841	GSK3B	S40	R45M	45	Missense	distal	5	no	9.026	8.571	EPSD	COSMIC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	Q9NYF8	BCLAF1	P49841	GSK3B	S40	S36Y	36	Missense	distal	-4	no	9.026	8.226	EPSD	COSMIC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	Q9NYF8	BCLAF1	P49841	GSK3B	S40	R37T	37	Missense	distal	-3	no	9.026	8.882	EPSD	COSMIC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	Q9NYF8	BCLAF1	P49841	GSK3B	S40	R47P	47	Missense	distal	7	no	9.026	8.525	EPSD	COSMIC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	Q9NYF8	BCLAF1	P49841	GSK3B	S40	R37K	37	Missense	distal	-3	no	9.026	8.881	EPSD	COSMIC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	Q9NYF8	BCLAF1	P49841	GSK3B	S40	S38F	38	Missense	proximal	-2	no	9.026	8.696	EPSD	COSMIC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	Q9NYF8	BCLAF1	P49841	GSK3B	S40	R39H	39	Missense	proximal	-1	no	9.026	9.112	EPSD	COSMIC	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	Q9NYF8	BCLAF1	P49841	GSK3B	S40	S36T	36	Missense	distal	-4	no	9.026	8.691	EPSD	COSMIC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	Q9NYF8	BCLAF1	P49841	GSK3B	S40	R37S	37	Missense	distal	-3	no	9.026	8.857	EPSD	COSMIC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	Q9NYF8	BCLAF1	P49841	GSK3B	T42	R37H	37	Missense	distal	-5	no	7.460	6.929	EPSD	COSMIC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	Q9NYF8	BCLAF1	P49841	GSK3B	T42	R49H	49	Missense	distal	7	no	7.460	7.648	EPSD	COSMIC	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	Q9NYF8	BCLAF1	P49841	GSK3B	T42	R49C	49	Missense	distal	7	no	7.460	7.414	EPSD	COSMIC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	Q9NYF8	BCLAF1	P49841	GSK3B	T42	S36F	36	Missense	distal	-6	no	7.460	7.406	EPSD	COSMIC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	Q9NYF8	BCLAF1	P49841	GSK3B	T42	R45P	45	Missense	distal	3	no	7.460	7.848	EPSD	COSMIC	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	Q9NYF8	BCLAF1	P49841	GSK3B	T42	S46I	46	Missense	distal	4	no	7.460	4.138	EPSD	COSMIC	6.007	Loss
CMGC_GSK_GSK3B_ST	Q9NYF8	BCLAF1	P49841	GSK3B	T42	R47T	47	Missense	distal	5	no	7.460	7.121	EPSD	COSMIC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	Q9NYF8	BCLAF1	P49841	GSK3B	T42	R45M	45	Missense	distal	3	no	7.460	7.640	EPSD	COSMIC	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	Q9NYF8	BCLAF1	P49841	GSK3B	T42	S36Y	36	Missense	distal	-6	no	7.460	7.373	EPSD	COSMIC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	Q9NYF8	BCLAF1	P49841	GSK3B	T42	R49T	49	Missense	distal	7	no	7.460	6.963	EPSD	COSMIC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	Q9NYF8	BCLAF1	P49841	GSK3B	T42	R37T	37	Missense	distal	-5	no	7.460	7.051	EPSD	COSMIC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	Q9NYF8	BCLAF1	P49841	GSK3B	T42	S48I	48	Missense	distal	6	no	7.460	7.459	EPSD	COSMIC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	Q9NYF8	BCLAF1	P49841	GSK3B	T42	R47P	47	Missense	distal	5	no	7.460	8.097	EPSD	COSMIC	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	Q9NYF8	BCLAF1	P49841	GSK3B	T42	R37K	37	Missense	distal	-5	no	7.460	6.963	EPSD	COSMIC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	Q9NYF8	BCLAF1	P49841	GSK3B	T42	S38F	38	Missense	distal	-4	no	7.460	6.306	EPSD	COSMIC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	Q9NYF8	BCLAF1	P49841	GSK3B	T42	R39H	39	Missense	distal	-3	no	7.460	7.403	EPSD	COSMIC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	Q9NYF8	BCLAF1	P49841	GSK3B	T42	S36T	36	Missense	distal	-6	no	7.460	7.402	EPSD	COSMIC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	Q9NYF8	BCLAF1	P49841	GSK3B	T42	R37S	37	Missense	distal	-5	no	7.460	6.762	EPSD	COSMIC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	Q9NYF8	BCLAF1	P49841	GSK3B	S44	R49H	49	Missense	distal	5	no	8.536	7.547	EPSD	COSMIC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	Q9NYF8	BCLAF1	P49841	GSK3B	S44	R49C	49	Missense	distal	5	no	8.536	6.980	EPSD	COSMIC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	Q9NYF8	BCLAF1	P49841	GSK3B	S44	R45P	45	Missense	proximal	1	no	8.536	10.856	EPSD	COSMIC	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	Q9NYF8	BCLAF1	P49841	GSK3B	S44	S46I	46	Missense	proximal	2	no	8.536	8.597	EPSD	COSMIC	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	Q9NYF8	BCLAF1	P49841	GSK3B	S44	R47T	47	Missense	distal	3	no	8.536	8.874	EPSD	COSMIC	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	Q9NYF8	BCLAF1	P49841	GSK3B	S44	R45M	45	Missense	proximal	1	no	8.536	7.269	EPSD	COSMIC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	Q9NYF8	BCLAF1	P49841	GSK3B	S44	R49T	49	Missense	distal	5	no	8.536	8.197	EPSD	COSMIC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	Q9NYF8	BCLAF1	P49841	GSK3B	S44	R37T	37	Missense	distal	-7	no	8.536	8.545	EPSD	COSMIC	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	Q9NYF8	BCLAF1	P49841	GSK3B	S44	D50V	50	Missense	distal	6	no	8.536	8.533	EPSD	COSMIC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	Q9NYF8	BCLAF1	P49841	GSK3B	S44	S48I	48	Missense	distal	4	no	8.536	5.214	EPSD	COSMIC	6.007	Loss
CMGC_GSK_GSK3B_ST	Q9NYF8	BCLAF1	P49841	GSK3B	S44	R47P	47	Missense	distal	3	no	8.536	8.925	EPSD	COSMIC	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	Q9NYF8	BCLAF1	P49841	GSK3B	S44	R37K	37	Missense	distal	-7	no	8.536	8.539	EPSD	COSMIC	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	Q9NYF8	BCLAF1	P49841	GSK3B	S44	S38F	38	Missense	distal	-6	no	8.536	8.483	EPSD	COSMIC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	Q9NYF8	BCLAF1	P49841	GSK3B	S44	R39H	39	Missense	distal	-5	no	8.536	8.005	EPSD	COSMIC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	Q9NYF8	BCLAF1	P49841	GSK3B	S44	R37S	37	Missense	distal	-7	no	8.536	8.518	EPSD	COSMIC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	Q9NYF8	BCLAF1	P49841	GSK3B	S46	R49H	49	Missense	distal	3	no	6.579	6.922	EPSD	COSMIC	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	Q9NYF8	BCLAF1	P49841	GSK3B	S46	R49C	49	Missense	distal	3	no	6.579	6.735	EPSD	COSMIC	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	Q9NYF8	BCLAF1	P49841	GSK3B	S46	R45P	45	Missense	proximal	-1	no	6.579	6.773	EPSD	COSMIC	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	Q9NYF8	BCLAF1	P49841	GSK3B	S46	S46I	46	Missense	central	0	yes	6.579	0.000	EPSD	COSMIC	6.007	Loss
CMGC_GSK_GSK3B_ST	Q9NYF8	BCLAF1	P49841	GSK3B	S46	R47T	47	Missense	proximal	1	no	6.579	5.708	EPSD	COSMIC	6.007	Loss
CMGC_GSK_GSK3B_ST	Q9NYF8	BCLAF1	P49841	GSK3B	S46	R45M	45	Missense	proximal	-1	no	6.579	6.666	EPSD	COSMIC	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	Q9NYF8	BCLAF1	P49841	GSK3B	S46	R49T	49	Missense	distal	3	no	6.579	6.918	EPSD	COSMIC	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	Q9NYF8	BCLAF1	P49841	GSK3B	S46	D50V	50	Missense	distal	4	no	6.579	6.613	EPSD	COSMIC	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	Q9NYF8	BCLAF1	P49841	GSK3B	S46	S48I	48	Missense	proximal	2	no	6.579	6.640	EPSD	COSMIC	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	Q9NYF8	BCLAF1	P49841	GSK3B	S46	R47P	47	Missense	proximal	1	no	6.579	8.899	EPSD	COSMIC	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	Q9NYF8	BCLAF1	P49841	GSK3B	S48	R49H	49	Missense	proximal	1	no	6.141	4.760	EPSD	COSMIC	6.007	Loss
CMGC_GSK_GSK3B_ST	Q9NYF8	BCLAF1	P49841	GSK3B	S48	R49C	49	Missense	proximal	1	no	6.141	4.138	EPSD	COSMIC	6.007	Loss
CMGC_GSK_GSK3B_ST	Q9NYF8	BCLAF1	P49841	GSK3B	S48	R45P	45	Missense	distal	-3	no	6.141	5.855	EPSD	COSMIC	6.007	Loss
CMGC_GSK_GSK3B_ST	Q9NYF8	BCLAF1	P49841	GSK3B	S48	S46I	46	Missense	proximal	-2	no	6.141	6.130	EPSD	COSMIC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	Q9NYF8	BCLAF1	P49841	GSK3B	S48	R47T	47	Missense	proximal	-1	no	6.141	6.203	EPSD	COSMIC	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	Q9NYF8	BCLAF1	P49841	GSK3B	S48	R45M	45	Missense	distal	-3	no	6.141	5.944	EPSD	COSMIC	6.007	Loss
CMGC_GSK_GSK3B_ST	Q9NYF8	BCLAF1	P49841	GSK3B	S48	R49T	49	Missense	proximal	1	no	6.141	5.270	EPSD	COSMIC	6.007	Loss
CMGC_GSK_GSK3B_ST	Q9NYF8	BCLAF1	P49841	GSK3B	S48	D50V	50	Missense	proximal	2	no	6.141	5.780	EPSD	COSMIC	6.007	Loss
CMGC_GSK_GSK3B_ST	Q9NYF8	BCLAF1	P49841	GSK3B	S48	S48I	48	Missense	central	0	yes	6.141	0.000	EPSD	COSMIC	6.007	Loss
CMGC_GSK_GSK3B_ST	Q9NYF8	BCLAF1	P49841	GSK3B	S48	R47P	47	Missense	proximal	-1	no	6.141	6.334	EPSD	COSMIC	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	Q9NYF8	BCLAF1	P49841	GSK3B	S54	R49H	49	Missense	distal	-5	no	6.057	5.527	EPSD	COSMIC	6.007	Loss
CMGC_GSK_GSK3B_ST	Q9NYF8	BCLAF1	P49841	GSK3B	S54	R49C	49	Missense	distal	-5	no	6.057	5.879	EPSD	COSMIC	6.007	Loss
CMGC_GSK_GSK3B_ST	Q9NYF8	BCLAF1	P49841	GSK3B	S54	R47T	47	Missense	distal	-7	no	6.057	6.066	EPSD	COSMIC	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	Q9NYF8	BCLAF1	P49841	GSK3B	S54	R49T	49	Missense	distal	-5	no	6.057	5.649	EPSD	COSMIC	6.007	Loss
CMGC_GSK_GSK3B_ST	Q9NYF8	BCLAF1	P49841	GSK3B	S54	R58H	58	Missense	distal	4	no	6.057	5.339	EPSD	COSMIC	6.007	Loss
CMGC_GSK_GSK3B_ST	Q9NYF8	BCLAF1	P49841	GSK3B	S54	D50V	50	Missense	distal	-4	no	6.057	5.424	EPSD	COSMIC	6.007	Loss
CMGC_GSK_GSK3B_ST	Q9NYF8	BCLAF1	P49841	GSK3B	S54	S48I	48	Missense	distal	-6	no	6.057	5.995	EPSD	COSMIC	6.007	Loss
CMGC_GSK_GSK3B_ST	Q9NYF8	BCLAF1	P49841	GSK3B	S54	R47P	47	Missense	distal	-7	no	6.057	6.038	EPSD	COSMIC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	Q9NYF8	BCLAF1	P49841	GSK3B	S104	R107C	107	Missense	distal	3	no	7.978	8.134	EPSD	COSMIC	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	Q9NYF8	BCLAF1	P49841	GSK3B	S104	R107S	107	Missense	distal	3	no	7.978	8.349	EPSD	COSMIC	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	Q9NYF8	BCLAF1	P49841	GSK3B	S104	S110Y	110	Missense	distal	6	no	7.978	7.972	EPSD	COSMIC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	Q9NYF8	BCLAF1	P49841	GSK3B	S104	R111W	111	Missense	distal	7	no	7.978	8.087	EPSD	COSMIC	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	Q9NYF8	BCLAF1	P49841	GSK3B	S104	R107L	107	Missense	distal	3	no	7.978	8.049	EPSD	COSMIC	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	Q9NYF8	BCLAF1	P49841	GSK3B	S104	R99T	99	Missense	distal	-5	no	7.978	7.570	EPSD	COSMIC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	Q9NYF8	BCLAF1	P49841	GSK3B	S104	N98D	98	Missense	distal	-6	no	7.978	7.956	EPSD	COSMIC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	Q9NYF8	BCLAF1	P49841	GSK3B	S104	S102F	102	Missense	proximal	-2	no	7.978	7.648	EPSD	COSMIC;GDSC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	Q9NYF8	BCLAF1	P49841	GSK3B	S104	H101N	101	Missense	distal	-3	no	7.978	7.772	EPSD	COSMIC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	Q9NYF8	BCLAF1	P49841	GSK3B	S114	R107C	107	Missense	distal	-7	no	7.790	7.794	EPSD	COSMIC	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	Q9NYF8	BCLAF1	P49841	GSK3B	S114	R107S	107	Missense	distal	-7	no	7.790	7.771	EPSD	COSMIC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	Q9NYF8	BCLAF1	P49841	GSK3B	S114	S110Y	110	Missense	distal	-4	no	7.790	6.989	EPSD	COSMIC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	Q9NYF8	BCLAF1	P49841	GSK3B	S114	R111W	111	Missense	distal	-3	no	7.790	7.720	EPSD	COSMIC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	Q9NYF8	BCLAF1	P49841	GSK3B	S114	R107L	107	Missense	distal	-7	no	7.790	7.771	EPSD	COSMIC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	Q9NYF8	BCLAF1	P49841	GSK3B	S114	R113W	113	Missense	proximal	-1	no	7.790	7.901	EPSD	COSMIC;GDSC;CCLE	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	Q9NYF8	BCLAF1	P49841	GSK3B	S114	V120I	120	Missense	distal	6	no	7.790	7.799	EPSD	COSMIC;GDSC;CCLE	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	Q9NYF8	BCLAF1	P49841	GSK3B	S121	R126K	126	Missense	distal	5	no	7.333	6.458	EPSD	COSMIC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	Q9NYF8	BCLAF1	P49841	GSK3B	S121	R128L	128	Missense	distal	7	no	7.333	6.881	EPSD	COSMIC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	Q9NYF8	BCLAF1	P49841	GSK3B	S121	R128C	128	Missense	distal	7	no	7.333	7.288	EPSD	COSMIC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	Q9NYF8	BCLAF1	P49841	GSK3B	S121	S127A	127	Missense	distal	6	no	7.333	7.331	EPSD	COSMIC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	Q9NYF8	BCLAF1	P49841	GSK3B	S121	Q123E	123	Missense	proximal	2	no	7.333	7.023	EPSD	COSMIC;GDSC;CCLE	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	Q9NYF8	BCLAF1	P49841	GSK3B	S121	R128T	128	Missense	distal	7	no	7.333	6.836	EPSD	COSMIC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	Q9NYF8	BCLAF1	P49841	GSK3B	S121	V120I	120	Missense	proximal	-1	no	7.333	7.135	EPSD	COSMIC;GDSC;CCLE	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	Q9NYF8	BCLAF1	P49841	GSK3B	S125	R126K	126	Missense	proximal	1	no	8.877	7.651	EPSD	COSMIC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	Q9NYF8	BCLAF1	P49841	GSK3B	S125	R128L	128	Missense	distal	3	no	8.877	8.947	EPSD	COSMIC	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	Q9NYF8	BCLAF1	P49841	GSK3B	S125	R128C	128	Missense	distal	3	no	8.877	9.032	EPSD	COSMIC	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	Q9NYF8	BCLAF1	P49841	GSK3B	S125	S127A	127	Missense	proximal	2	no	8.877	8.885	EPSD	COSMIC	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	Q9NYF8	BCLAF1	P49841	GSK3B	S125	Q123E	123	Missense	proximal	-2	no	8.877	8.819	EPSD	COSMIC;GDSC;CCLE	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	Q9NYF8	BCLAF1	P49841	GSK3B	S125	R131W	131	Missense	distal	6	no	8.877	8.866	EPSD	COSMIC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	Q9NYF8	BCLAF1	P49841	GSK3B	S125	R128T	128	Missense	distal	3	no	8.877	9.215	EPSD	COSMIC	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	Q9NYF8	BCLAF1	P49841	GSK3B	S125	R130L	130	Missense	distal	5	no	8.877	8.234	EPSD	COSMIC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	Q9NYF8	BCLAF1	P49841	GSK3B	S125	V120I	120	Missense	distal	-5	no	8.877	8.770	EPSD	COSMIC;GDSC;CCLE	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	Q9NYF8	BCLAF1	P49841	GSK3B	S136	R140S	140	Missense	distal	4	no	5.943	8.980	EPSD	COSMIC	6.007	Gain
CMGC_GSK_GSK3B_ST	Q9NYF8	BCLAF1	P49841	GSK3B	S138	R140S	140	Missense	proximal	2	no	10.710	10.692	EPSD	COSMIC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	Q9NYF8	BCLAF1	P49841	GSK3B	S138	R131W	131	Missense	distal	-7	no	10.710	10.720	EPSD	COSMIC	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	Q9NYF8	BCLAF1	P49841	GSK3B	S138	R145H	145	Missense	distal	7	no	10.710	10.898	EPSD	COSMIC	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	Q9NYF8	BCLAF1	P49841	GSK3B	S143	P149S	149	Missense	distal	6	no	6.597	6.595	EPSD	COSMIC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	Q9NYF8	BCLAF1	P49841	GSK3B	S143	R140S	140	Missense	distal	-3	no	6.597	6.428	EPSD	COSMIC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	Q9NYF8	BCLAF1	P49841	GSK3B	S143	Y150C	150	Missense	distal	7	no	6.597	6.547	EPSD	COSMIC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	Q9NYF8	BCLAF1	P49841	GSK3B	S143	R145H	145	Missense	proximal	2	no	6.597	6.254	EPSD	COSMIC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	Q9NYF8	BCLAF1	P49841	GSK3B	S143	Y150N	150	Missense	distal	7	no	6.597	6.278	EPSD	COSMIC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	Q9NYF8	BCLAF1	P49841	GSK3B	S143	S148T	148	Missense	distal	5	no	6.597	6.575	EPSD	COSMIC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	Q9NYF8	BCLAF1	P49841	GSK3B	S147	P149S	149	Missense	proximal	2	no	6.286	5.842	EPSD	COSMIC	6.007	Loss
CMGC_GSK_GSK3B_ST	Q9NYF8	BCLAF1	P49841	GSK3B	S147	P154S	154	Missense	distal	7	no	6.286	6.349	EPSD	COSMIC	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	Q9NYF8	BCLAF1	P49841	GSK3B	S147	R140S	140	Missense	distal	-7	no	6.286	6.268	EPSD	COSMIC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	Q9NYF8	BCLAF1	P49841	GSK3B	S147	Y150C	150	Missense	distal	3	no	6.286	6.492	EPSD	COSMIC	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	Q9NYF8	BCLAF1	P49841	GSK3B	S147	R145H	145	Missense	proximal	-2	no	6.286	6.296	EPSD	COSMIC	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	Q9NYF8	BCLAF1	P49841	GSK3B	S147	Y150N	150	Missense	distal	3	no	6.286	6.756	EPSD	COSMIC	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	Q9NYF8	BCLAF1	P49841	GSK3B	S147	S148T	148	Missense	proximal	1	no	6.286	6.940	EPSD	COSMIC	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	Q9NYF8	BCLAF1	P49841	GSK3B	S148	P149S	149	Missense	proximal	1	no	7.086	3.241	EPSD	COSMIC	6.007	Loss
CMGC_GSK_GSK3B_ST	Q9NYF8	BCLAF1	P49841	GSK3B	S148	P154S	154	Missense	distal	6	no	7.086	7.084	EPSD	COSMIC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	Q9NYF8	BCLAF1	P49841	GSK3B	S148	Y150C	150	Missense	proximal	2	no	7.086	6.826	EPSD	COSMIC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	Q9NYF8	BCLAF1	P49841	GSK3B	S148	R145H	145	Missense	distal	-3	no	7.086	7.029	EPSD	COSMIC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	Q9NYF8	BCLAF1	P49841	GSK3B	S148	Y150N	150	Missense	proximal	2	no	7.086	6.786	EPSD	COSMIC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	Q9NYF8	BCLAF1	P49841	GSK3B	S153	P149S	149	Missense	distal	-4	no	7.955	8.518	EPSD	COSMIC	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	Q9NYF8	BCLAF1	P49841	GSK3B	S153	P154S	154	Missense	proximal	1	no	7.955	4.110	EPSD	COSMIC	6.007	Loss
CMGC_GSK_GSK3B_ST	Q9NYF8	BCLAF1	P49841	GSK3B	S153	Y150C	150	Missense	distal	-3	no	7.955	7.918	EPSD	COSMIC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	Q9NYF8	BCLAF1	P49841	GSK3B	S153	S156Y	156	Missense	distal	3	no	7.955	7.532	EPSD	COSMIC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	Q9NYF8	BCLAF1	P49841	GSK3B	S153	Y150N	150	Missense	distal	-3	no	7.955	7.720	EPSD	COSMIC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	Q9NYF8	BCLAF1	P49841	GSK3B	S153	S148T	148	Missense	distal	-5	no	7.955	8.244	EPSD	COSMIC	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	Q9NYF8	BCLAF1	P49841	GSK3B	S177	P178S	178	Missense	proximal	1	no	10.456	6.611	EPSD	COSMIC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	Q9NYF8	BCLAF1	P49841	GSK3B	S177	S181G	181	Missense	distal	4	no	10.456	7.213	EPSD	COSMIC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	Q9NYF8	BCLAF1	P49841	GSK3B	S177	P178Q	178	Missense	proximal	1	no	10.456	7.188	EPSD	COSMIC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	Q9NYF8	BCLAF1	P49841	GSK3B	S177	E176G	176	Missense	proximal	-1	no	10.456	10.474	EPSD	COSMIC	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	Q9NYF8	BCLAF1	P49841	GSK3B	S177	G171E	171	Missense	distal	-6	no	10.456	10.378	EPSD	COSMIC;GDSC;CCLE	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	Q9NYF8	BCLAF1	P49841	GSK3B	S177	P178L	178	Missense	proximal	1	no	10.456	7.595	EPSD	COSMIC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	Q9NYF8	BCLAF1	P49841	GSK3B	S205	D200H	200	Missense	distal	-5	no	6.387	6.281	EPSD	COSMIC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	Q9NYF8	BCLAF1	P49841	GSK3B	S205	G210V	210	Missense	distal	5	no	6.387	5.843	EPSD	COSMIC	6.007	Loss
CMGC_GSK_GSK3B_ST	Q9NYF8	BCLAF1	P49841	GSK3B	S205	S205L	205	Missense	central	0	yes	6.387	0.000	EPSD	COSMIC;GDSC;CCLE	6.007	Loss
CMGC_GSK_GSK3B_ST	Q9NYF8	BCLAF1	P49841	GSK3B	S205	S209P	209	Missense	distal	4	no	6.387	3.415	EPSD	COSMIC	6.007	Loss
CMGC_GSK_GSK3B_ST	Q9NYF8	BCLAF1	P49841	GSK3B	S205	T208K	208	Missense	distal	3	no	6.387	6.293	EPSD	COSMIC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	Q9NYF8	BCLAF1	P49841	GSK3B	S222	S228L	228	Missense	distal	6	no	6.497	6.492	EPSD	COSMIC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	Q9NYF8	BCLAF1	P49841	GSK3B	S222	S222N	222	Missense	central	0	yes	6.497	0.000	EPSD	COSMIC;GDSC;CCLE	6.007	Loss
CMGC_GSK_GSK3B_ST	Q9NYF8	BCLAF1	P49841	GSK3B	S222	R224T	224	Missense	proximal	2	no	6.497	6.605	EPSD	COSMIC;GDSC;CCLE	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	Q9NYF8	BCLAF1	P49841	GSK3B	S225	S228L	228	Missense	distal	3	no	6.242	5.941	EPSD	COSMIC	6.007	Loss
CMGC_GSK_GSK3B_ST	Q9NYF8	BCLAF1	P49841	GSK3B	S225	S222N	222	Missense	distal	-3	no	6.242	6.147	EPSD	COSMIC;GDSC;CCLE	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	Q9NYF8	BCLAF1	P49841	GSK3B	S225	S222T	222	Missense	distal	-3	no	6.242	6.267	EPSD	COSMIC	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	Q9NYF8	BCLAF1	P49841	GSK3B	S225	R224T	224	Missense	proximal	-1	no	6.242	6.304	EPSD	COSMIC;GDSC;CCLE	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	Q9NYF8	BCLAF1	P49841	GSK3B	S225	I232V	232	Missense	distal	7	no	6.242	6.332	EPSD	COSMIC	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	Q9NYF8	BCLAF1	P49841	GSK3B	S228	S228L	228	Missense	central	0	yes	7.154	0.000	EPSD	COSMIC	6.007	Loss
CMGC_GSK_GSK3B_ST	Q9NYF8	BCLAF1	P49841	GSK3B	S228	S222N	222	Missense	distal	-6	no	7.154	7.152	EPSD	COSMIC;GDSC;CCLE	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	Q9NYF8	BCLAF1	P49841	GSK3B	S228	S222T	222	Missense	distal	-6	no	7.154	7.096	EPSD	COSMIC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	Q9NYF8	BCLAF1	P49841	GSK3B	S228	R224T	224	Missense	distal	-4	no	7.154	8.006	EPSD	COSMIC;GDSC;CCLE	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	Q9NYF8	BCLAF1	P49841	GSK3B	S228	A233T	233	Missense	distal	5	no	7.154	7.207	EPSD	COSMIC	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	Q9NYF8	BCLAF1	P49841	GSK3B	S228	I232V	232	Missense	distal	4	no	7.154	8.086	EPSD	COSMIC	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	Q9NYF8	BCLAF1	P49841	GSK3B	S230	S228L	228	Missense	proximal	-2	no	8.932	8.858	EPSD	COSMIC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	Q9NYF8	BCLAF1	P49841	GSK3B	S230	A233T	233	Missense	distal	3	no	8.932	9.237	EPSD	COSMIC	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	Q9NYF8	BCLAF1	P49841	GSK3B	S230	I232V	232	Missense	proximal	2	no	8.932	8.603	EPSD	COSMIC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	Q9NYF8	BCLAF1	P49841	GSK3B	S239	A233T	233	Missense	distal	-6	no	6.553	6.485	EPSD	COSMIC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	Q9NYF8	BCLAF1	P49841	GSK3B	S239	S243Y	243	Missense	distal	4	no	6.553	3.040	EPSD	COSMIC	6.007	Loss
CMGC_GSK_GSK3B_ST	Q9NYF8	BCLAF1	P49841	GSK3B	S239	I232V	232	Missense	distal	-7	no	6.553	6.547	EPSD	COSMIC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	Q9NYF8	BCLAF1	P49841	GSK3B	S249	S249R	249	Missense	central	0	yes	7.274	0.000	EPSD	COSMIC	6.007	Loss
CMGC_GSK_GSK3B_ST	Q9NYF8	BCLAF1	P49841	GSK3B	S249	M247V	247	Missense	proximal	-2	no	7.274	7.573	EPSD	COSMIC	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	Q9NYF8	BCLAF1	P49841	GSK3B	S249	L248R	248	Missense	proximal	-1	no	7.274	7.212	EPSD	COSMIC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	Q9NYF8	BCLAF1	P49841	GSK3B	S249	S243Y	243	Missense	distal	-6	no	7.274	7.188	EPSD	COSMIC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	Q9NYF8	BCLAF1	P49841	GSK3B	S253	S249R	249	Missense	distal	-4	no	7.196	6.009	EPSD	COSMIC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	Q9NYF8	BCLAF1	P49841	GSK3B	S253	M247V	247	Missense	distal	-6	no	7.196	7.182	EPSD	COSMIC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	Q9NYF8	BCLAF1	P49841	GSK3B	S253	L248R	248	Missense	distal	-5	no	7.196	7.785	EPSD	COSMIC	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	Q9NYF8	BCLAF1	P49841	GSK3B	T257	H261L	261	Missense	distal	4	no	5.770	6.808	EPSD	COSMIC	6.007	Gain
CMGC_GSK_GSK3B_ST	Q9NYF8	BCLAF1	P49841	GSK3B	S264	H261L	261	Missense	distal	-3	no	7.837	7.735	EPSD	COSMIC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	Q9NYF8	BCLAF1	P49841	GSK3B	S268	H261L	261	Missense	distal	-7	no	8.909	8.891	EPSD	COSMIC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	Q9NYF8	BCLAF1	P49841	GSK3B	S268	S274F	274	Missense	distal	6	no	8.909	8.896	EPSD	COSMIC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	Q9NYF8	BCLAF1	P49841	GSK3B	S268	G273V	273	Missense	distal	5	no	8.909	8.365	EPSD	COSMIC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	Q9NYF8	BCLAF1	P49841	GSK3B	S268	G273W	273	Missense	distal	5	no	8.909	7.881	EPSD	COSMIC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	Q9NYF8	BCLAF1	P49841	GSK3B	S272	S274F	274	Missense	proximal	2	no	7.067	6.723	EPSD	COSMIC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	Q9NYF8	BCLAF1	P49841	GSK3B	S272	G273V	273	Missense	proximal	1	no	7.067	7.271	EPSD	COSMIC	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	Q9NYF8	BCLAF1	P49841	GSK3B	S272	G278V	278	Missense	distal	6	no	7.067	7.061	EPSD	COSMIC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	Q9NYF8	BCLAF1	P49841	GSK3B	S272	G273W	273	Missense	proximal	1	no	7.067	8.160	EPSD	COSMIC	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	Q9NYF8	BCLAF1	P49841	GSK3B	S272	G278E	278	Missense	distal	6	no	7.067	7.065	EPSD	COSMIC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	Q9NYF8	BCLAF1	P49841	GSK3B	S281	S274F	274	Missense	distal	-7	no	6.424	6.434	EPSD	COSMIC	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	Q9NYF8	BCLAF1	P49841	GSK3B	S281	S282G	282	Missense	proximal	1	no	6.424	7.075	EPSD	COSMIC	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	Q9NYF8	BCLAF1	P49841	GSK3B	S281	G278V	278	Missense	distal	-3	no	6.424	6.595	EPSD	COSMIC	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	Q9NYF8	BCLAF1	P49841	GSK3B	S281	G278E	278	Missense	distal	-3	no	6.424	6.442	EPSD	COSMIC	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	Q9NYF8	BCLAF1	P49841	GSK3B	S285	S282G	282	Missense	distal	-3	no	7.515	7.511	EPSD	COSMIC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	Q9NYF8	BCLAF1	P49841	GSK3B	S285	G278V	278	Missense	distal	-7	no	7.515	7.538	EPSD	COSMIC	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	Q9NYF8	BCLAF1	P49841	GSK3B	S285	G278E	278	Missense	distal	-7	no	7.515	7.549	EPSD	COSMIC	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	Q9NYF8	BCLAF1	P49841	GSK3B	S285	P291L	291	Missense	distal	6	no	7.515	7.508	EPSD	COSMIC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	Q9NYF8	BCLAF1	P49841	GSK3B	S297	P301S	301	Missense	distal	4	no	4.505	7.476	EPSD	COSMIC	6.007	Gain
CMGC_GSK_GSK3B_ST	Q9NYF8	BCLAF1	P49841	GSK3B	S297	P301T	301	Missense	distal	4	no	4.505	6.607	EPSD	COSMIC	6.007	Gain
CMGC_GSK_GSK3B_ST	Q9NYF8	BCLAF1	P49841	GSK3B	S300	P301S	301	Missense	proximal	1	no	8.714	4.869	EPSD	COSMIC	6.007	Loss
CMGC_GSK_GSK3B_ST	Q9NYF8	BCLAF1	P49841	GSK3B	S300	R298Q	298	Missense	proximal	-2	no	8.714	8.785	EPSD	COSMIC;GDSC	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	Q9NYF8	BCLAF1	P49841	GSK3B	S300	A306S	306	Missense	distal	6	no	8.714	8.716	EPSD	COSMIC	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	Q9NYF8	BCLAF1	P49841	GSK3B	S300	P301T	301	Missense	proximal	1	no	8.714	5.523	EPSD	COSMIC	6.007	Loss
CMGC_GSK_GSK3B_ST	Q9NYF8	BCLAF1	P49841	GSK3B	S300	P301H	301	Missense	proximal	1	no	8.714	5.014	EPSD	COSMIC	6.007	Loss
CMGC_GSK_GSK3B_ST	Q9NYF8	BCLAF1	P49841	GSK3B	S315	R316C	316	Missense	proximal	1	no	8.876	6.873	EPSD	COSMIC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	Q9NYF8	BCLAF1	P49841	GSK3B	S315	P311S	311	Missense	distal	-4	no	8.876	9.439	EPSD	COSMIC	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	Q9NYF8	BCLAF1	P49841	GSK3B	S315	S319F	319	Missense	distal	4	no	8.876	5.262	EPSD	COSMIC	6.007	Loss
CMGC_GSK_GSK3B_ST	Q9NYF8	BCLAF1	P49841	GSK3B	S315	P311Q	311	Missense	distal	-4	no	8.876	8.610	EPSD	COSMIC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	Q9NYF8	BCLAF1	P49841	GSK3B	S315	E314K	314	Missense	proximal	-1	no	8.876	8.943	EPSD	COSMIC;GDSC	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	Q9NYF8	BCLAF1	P49841	GSK3B	S315	Q308H	308	Missense	distal	-7	no	8.876	8.879	EPSD	COSMIC	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	Q9NYF8	BCLAF1	P49841	GSK3B	S385	G390R	390	Missense	distal	5	no	6.855	7.129	EPSD	COSMIC;GDSC;CCLE	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	Q9NYF8	BCLAF1	P49841	GSK3B	S385	E379K	379	Missense	distal	-6	no	6.855	6.854	EPSD	COSMIC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	Q9NYF8	BCLAF1	P49841	GSK3B	S385	D386G	386	Missense	proximal	1	no	6.855	6.764	EPSD	COSMIC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	Q9NYF8	BCLAF1	P49841	GSK3B	S389	G390R	390	Missense	proximal	1	no	5.564	6.439	EPSD	COSMIC;GDSC;CCLE	6.007	Gain
CMGC_GSK_GSK3B_ST	Q9NYF8	BCLAF1	P49841	GSK3B	S427	S422C	422	Missense	distal	-5	no	5.806	6.326	EPSD	COSMIC	6.007	Gain
CMGC_GSK_GSK3B_ST	Q9NYF8	BCLAF1	P49841	GSK3B	S512	P513S	513	Missense	proximal	1	no	6.049	2.204	EPSD	COSMIC	6.007	Loss
CMGC_GSK_GSK3B_ST	Q9NYF8	BCLAF1	P49841	GSK3B	S512	N518D	518	Missense	distal	6	no	6.049	6.048	EPSD	COSMIC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	Q9NYF8	BCLAF1	P49841	GSK3B	S512	N518H	518	Missense	distal	6	no	6.049	6.046	EPSD	COSMIC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	Q9NYF8	BCLAF1	P49841	GSK3B	S512	F509L	509	Missense	distal	-3	no	6.049	5.992	EPSD	COSMIC	6.007	Loss
CMGC_GSK_GSK3B_ST	Q9NYF8	BCLAF1	P49841	GSK3B	S512	L519M	519	Missense	distal	7	no	6.049	6.432	EPSD	COSMIC;GDSC;CCLE	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	Q9NYF8	BCLAF1	P49841	GSK3B	S531	R534S	534	Missense	distal	3	no	5.793	6.163	PhosphoSitePlus	COSMIC	6.007	Gain
CMGC_GSK_GSK3B_ST	Q9NYF8	BCLAF1	P49841	GSK3B	T644	R645W	645	Missense	proximal	1	no	9.401	9.619	EPSD	COSMIC	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	Q9NYF8	BCLAF1	P49841	GSK3B	T644	R645L	645	Missense	proximal	1	no	9.401	8.861	EPSD	COSMIC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	Q9NYF8	BCLAF1	P49841	GSK3B	S658	H665D	665	Missense	distal	7	no	8.786	8.215	EPSD	COSMIC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	Q9NYF8	BCLAF1	P49841	GSK3B	S658	D656V	656	Missense	proximal	-2	no	8.786	8.769	EPSD	COSMIC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	Q9NYF8	BCLAF1	P49841	GSK3B	S658	L662M	662	Missense	distal	4	no	8.786	9.269	EPSD	COSMIC	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	Q9NYF8	BCLAF1	P49841	GSK3B	S658	D656G	656	Missense	proximal	-2	no	8.786	8.684	EPSD	COSMIC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	Q9NYF8	BCLAF1	P49841	GSK3B	S658	R654I	654	Missense	distal	-4	no	8.786	7.490	EPSD	COSMIC;GDSC;CCLE	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	Q9NYF8	BCLAF1	P49841	GSK3B	S714	S718R	718	Missense	distal	4	no	8.636	5.598	EPSD	COSMIC	6.007	Loss
CMGC_GSK_GSK3B_ST	Q9NYF8	BCLAF1	P49841	GSK3B	S714	S711F	711	Missense	distal	-3	no	8.636	8.702	EPSD	COSMIC	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	Q9NYF8	BCLAF1	P49841	GSK3B	S714	R715M	715	Missense	proximal	1	no	8.636	7.369	EPSD	COSMIC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	Q9NYF8	BCLAF1	P49841	GSK3B	S714	G719E	719	Missense	distal	5	no	8.636	8.902	EPSD	COSMIC	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	Q9NYF8	BCLAF1	P49841	GSK3B	S714	S711T	711	Missense	distal	-3	no	8.636	8.661	EPSD	COSMIC	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	Q9NYF8	BCLAF1	P49841	GSK3B	S714	G709D	709	Missense	distal	-5	no	8.636	8.442	EPSD	COSMIC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	Q9NYF8	BCLAF1	P49841	GSK3B	S714	G709C	709	Missense	distal	-5	no	8.636	8.689	EPSD	COSMIC	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	Q9NYF8	BCLAF1	P49841	GSK3B	T726	G719E	719	Missense	distal	-7	no	7.054	7.089	EPSD	COSMIC	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	Q9NYF8	BCLAF1	P49841	GSK3B	S749	S751Y	751	Missense	proximal	2	no	7.933	7.700	EPSD	COSMIC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	Q9NYF8	BCLAF1	P49841	GSK3B	S749	S751C	751	Missense	proximal	2	no	7.933	7.440	EPSD	COSMIC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	Q9NYF8	BCLAF1	P49841	GSK3B	S749	R750L	750	Missense	proximal	1	no	7.933	7.392	EPSD	COSMIC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	Q9NYF8	BCLAF1	P49841	GSK3B	S749	A756T	756	Missense	distal	7	no	7.933	7.526	EPSD	COSMIC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	Q9NYF8	BCLAF1	P49841	GSK3B	S749	S753C	753	Missense	distal	4	no	7.933	1.800	EPSD	COSMIC	6.007	Loss
CMGC_GSK_GSK3B_ST	Q9NYF8	BCLAF1	P49841	GSK3B	S749	K743R	743	Missense	distal	-6	no	7.933	7.938	EPSD	COSMIC	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	Q9NYF8	BCLAF1	P49841	GSK3B	S751	S751Y	751	Missense	central	0	yes	7.694	0.000	EPSD	COSMIC	6.007	Loss
CMGC_GSK_GSK3B_ST	Q9NYF8	BCLAF1	P49841	GSK3B	S751	S751C	751	Missense	central	0	yes	7.694	0.000	EPSD	COSMIC	6.007	Loss
CMGC_GSK_GSK3B_ST	Q9NYF8	BCLAF1	P49841	GSK3B	S751	P758T	758	Missense	distal	7	no	7.694	7.698	EPSD	COSMIC	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	Q9NYF8	BCLAF1	P49841	GSK3B	S751	R750L	750	Missense	proximal	-1	no	7.694	7.756	EPSD	COSMIC	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	Q9NYF8	BCLAF1	P49841	GSK3B	S751	A756T	756	Missense	distal	5	no	7.694	7.746	EPSD	COSMIC	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	Q9NYF8	BCLAF1	P49841	GSK3B	S751	S753C	753	Missense	proximal	2	no	7.694	7.202	EPSD	COSMIC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	Q9NYF8	BCLAF1	P49841	GSK3B	S753	A756T	756	Missense	distal	3	no	5.879	6.183	EPSD	COSMIC	6.007	Gain
CMGC_GSK_GSK3B_ST	Q9NYF8	BCLAF1	P49841	GSK3B	S755	S751Y	751	Missense	distal	-4	no	7.502	6.702	EPSD	COSMIC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	Q9NYF8	BCLAF1	P49841	GSK3B	S755	S751C	751	Missense	distal	-4	no	7.502	5.388	EPSD	COSMIC	6.007	Loss
CMGC_GSK_GSK3B_ST	Q9NYF8	BCLAF1	P49841	GSK3B	S755	P758T	758	Missense	distal	3	no	7.502	7.452	EPSD	COSMIC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	Q9NYF8	BCLAF1	P49841	GSK3B	S755	R750L	750	Missense	distal	-5	no	7.502	6.914	EPSD	COSMIC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	Q9NYF8	BCLAF1	P49841	GSK3B	S755	A756T	756	Missense	proximal	1	no	7.502	8.044	EPSD	COSMIC	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	Q9NYF8	BCLAF1	P49841	GSK3B	S755	P761H	761	Missense	distal	6	no	7.502	7.490	EPSD	COSMIC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	Q9NYF8	BCLAF1	P49841	GSK3B	S755	S753C	753	Missense	proximal	-2	no	7.502	7.191	EPSD	COSMIC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	Q9NYF8	BCLAF1	P49841	GSK3B	S757	S751Y	751	Missense	distal	-6	no	8.512	8.426	EPSD	COSMIC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	Q9NYF8	BCLAF1	P49841	GSK3B	S757	S751C	751	Missense	distal	-6	no	8.512	8.501	EPSD	COSMIC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	Q9NYF8	BCLAF1	P49841	GSK3B	S757	P758T	758	Missense	proximal	1	no	8.512	5.321	EPSD	COSMIC	6.007	Loss
CMGC_GSK_GSK3B_ST	Q9NYF8	BCLAF1	P49841	GSK3B	S757	R750L	750	Missense	distal	-7	no	8.512	8.494	EPSD	COSMIC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	Q9NYF8	BCLAF1	P49841	GSK3B	S757	A756T	756	Missense	proximal	-1	no	8.512	8.592	EPSD	COSMIC	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	Q9NYF8	BCLAF1	P49841	GSK3B	S757	R764Q	764	Missense	distal	7	no	8.512	8.165	EPSD	COSMIC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	Q9NYF8	BCLAF1	P49841	GSK3B	S757	P761H	761	Missense	distal	4	no	8.512	7.728	EPSD	COSMIC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	Q9NYF8	BCLAF1	P49841	GSK3B	S757	S753C	753	Missense	distal	-4	no	8.512	6.398	EPSD	COSMIC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	Q9NYF8	BCLAF1	P49841	GSK3B	S759	P758T	758	Missense	proximal	-1	no	7.745	7.614	EPSD	COSMIC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	Q9NYF8	BCLAF1	P49841	GSK3B	S759	A756T	756	Missense	distal	-3	no	7.745	7.750	EPSD	COSMIC	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	Q9NYF8	BCLAF1	P49841	GSK3B	S759	R764Q	764	Missense	distal	5	no	7.745	7.407	EPSD	COSMIC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	Q9NYF8	BCLAF1	P49841	GSK3B	S759	P761H	761	Missense	proximal	2	no	7.745	6.976	EPSD	COSMIC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	Q9NYF8	BCLAF1	P49841	GSK3B	S759	S753C	753	Missense	distal	-6	no	7.745	7.734	EPSD	COSMIC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	Q9NYF8	BCLAF1	P49841	GSK3B	S760	P758T	758	Missense	proximal	-2	no	7.612	7.383	EPSD	COSMIC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	Q9NYF8	BCLAF1	P49841	GSK3B	S760	A756T	756	Missense	distal	-4	no	7.612	8.436	EPSD	COSMIC	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	Q9NYF8	BCLAF1	P49841	GSK3B	S760	R764Q	764	Missense	distal	4	no	7.612	7.087	EPSD	COSMIC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	Q9NYF8	BCLAF1	P49841	GSK3B	S760	P761H	761	Missense	proximal	1	no	7.612	3.912	EPSD	COSMIC	6.007	Loss
CMGC_GSK_GSK3B_ST	Q9NYF8	BCLAF1	P49841	GSK3B	S760	S753C	753	Missense	distal	-7	no	7.612	7.635	EPSD	COSMIC	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	Q9NYF8	BCLAF1	P49841	GSK3B	S763	P758T	758	Missense	distal	-5	no	5.817	6.262	EPSD	COSMIC	6.007	Gain
CMGC_GSK_GSK3B_ST	Q9NYF8	BCLAF1	P49841	GSK3B	T817	N821T	821	Missense	distal	4	no	3.894	6.635	EPSD	COSMIC	6.007	Gain
CMGC_GSK_GSK3B_ST	Q9NYF8	BCLAF1	P49841	GSK3B	S884	S881C	881	Missense	distal	-3	no	8.318	8.422	EPSD	COSMIC	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	Q9NYF8	BCLAF1	P49841	GSK3B	S884	S881N	881	Missense	distal	-3	no	8.318	8.224	EPSD	COSMIC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	Q9NYF8	BCLAF1	P49841	GSK3B	S884	S883N	883	Missense	proximal	-1	no	8.318	8.380	EPSD	COSMIC	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	Q9NYF8	BCLAF1	P49841	GSK3B	S884	T888N	888	Missense	distal	4	no	8.318	5.577	EPSD	COSMIC	6.007	Loss
CMGC_GSK_GSK3B_ST	Q9NYF8	BCLAF1	P49841	GSK3B	S884	G882D	882	Missense	proximal	-2	no	8.318	8.420	EPSD	COSMIC	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	Q9NYF8	BCLAF1	P49841	GSK3B	S884	F878L	878	Missense	distal	-6	no	8.318	8.371	EPSD	COSMIC	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	Q9NYF8	BCLAF1	P49841	GSK3B	S884	G882C	882	Missense	proximal	-2	no	8.318	8.125	EPSD	COSMIC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	Q9NYF8	BCLAF1	P49841	GSK3B	S884	K891Q	891	Missense	distal	7	no	8.318	8.478	EPSD	COSMIC	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	O75030	MITF	P49841	GSK3B	S176	A177V	177	Missense	proximal	1	no	6.901	7.642	EPSD	COSMIC	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	O75030	MITF	P49841	GSK3B	S176	N179I	179	Missense	distal	3	no	6.901	6.432	EPSD	COSMIC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	O75030	MITF	P49841	GSK3B	S176	P170L	170	Missense	distal	-6	no	6.901	6.879	EPSD	COSMIC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	O75030	MITF	P49841	GSK3B	S176	P170S	170	Missense	distal	-6	no	6.901	6.880	EPSD	COSMIC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	O75030	MITF	P49841	GSK3B	S180	A177V	177	Missense	distal	-3	no	8.658	8.805	EPSD	COSMIC	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	O75030	MITF	P49841	GSK3B	S180	N179I	179	Missense	proximal	-1	no	8.658	8.447	EPSD	COSMIC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	O75030	MITF	P49841	GSK3B	S405	L406H	406	Missense	proximal	1	no	6.770	5.930	EPSD;PhosphoSitePlus	COSMIC	6.007	Loss
CMGC_GSK_GSK3B_ST	O75030	MITF	P49841	GSK3B	S405	A399D	399	Missense	distal	-6	no	6.770	6.734	EPSD;PhosphoSitePlus	COSMIC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	O75030	MITF	P49841	GSK3B	S405	S405I	405	Missense	central	0	yes	6.770	0.000	EPSD;PhosphoSitePlus	COSMIC	6.007	Loss
CMGC_GSK_GSK3B_ST	O75030	MITF	P49841	GSK3B	S405	R400W	400	Missense	distal	-5	no	6.770	6.514	EPSD;PhosphoSitePlus	COSMIC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	O75030	MITF	P49841	GSK3B	T410	S405I	405	Missense	distal	-5	no	5.690	6.162	EPSD	COSMIC	6.007	Gain
CMGC_GSK_GSK3B_ST	O75030	MITF	P49841	GSK3B	S414	R420Q	420	Missense	distal	6	no	7.354	7.355	EPSD	COSMIC	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	O75030	MITF	P49841	GSK3B	S414	C413F	413	Missense	proximal	-1	no	7.354	7.260	EPSD	COSMIC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	O75030	MITF	P49841	GSK3B	S491	V493I	493	Missense	proximal	2	no	6.724	7.054	EPSD	COSMIC	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	O75030	MITF	P49841	GSK3B	S491	D487N	487	Missense	distal	-4	no	6.724	6.027	EPSD	COSMIC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	O75030	MITF	P49841	GSK3B	S491	T489N	489	Missense	proximal	-2	no	6.724	6.468	EPSD	COSMIC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	O75030	MITF	P49841	GSK3B	S504	S504F	504	Missense	central	0	yes	9.447	0.000	EPSD	COSMIC	6.007	Loss
CMGC_GSK_GSK3B_ST	O75030	MITF	P49841	GSK3B	S504	A507T	507	Missense	distal	3	no	9.447	9.752	EPSD	COSMIC	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	O75030	MITF	P49841	GSK3B	S504	S511I	511	Missense	distal	7	no	9.447	9.783	EPSD	COSMIC	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	O75030	MITF	P49841	GSK3B	S508	S512I	512	Missense	distal	4	no	7.924	4.602	EPSD	COSMIC	6.007	Loss
CMGC_GSK_GSK3B_ST	O75030	MITF	P49841	GSK3B	S508	S504F	504	Missense	distal	-4	no	7.924	6.770	EPSD	COSMIC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	O75030	MITF	P49841	GSK3B	S508	A507T	507	Missense	proximal	-1	no	7.924	8.003	EPSD	COSMIC	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	O75030	MITF	P49841	GSK3B	S508	R513W	513	Missense	distal	5	no	7.924	6.622	EPSD	COSMIC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	O75030	MITF	P49841	GSK3B	S508	S511I	511	Missense	distal	3	no	7.924	7.504	EPSD	COSMIC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	O75030	MITF	P49841	GSK3B	S511	S512I	512	Missense	proximal	1	no	6.054	6.018	EPSD	COSMIC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	O75030	MITF	P49841	GSK3B	S511	S504F	504	Missense	distal	-7	no	6.054	6.064	EPSD	COSMIC	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	O75030	MITF	P49841	GSK3B	S511	A507T	507	Missense	distal	-4	no	6.054	6.878	EPSD	COSMIC	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	O75030	MITF	P49841	GSK3B	S511	R513W	513	Missense	proximal	2	no	6.054	5.624	EPSD	COSMIC	6.007	Loss
CMGC_GSK_GSK3B_ST	O75030	MITF	P49841	GSK3B	S511	S518I	518	Missense	distal	7	no	6.054	6.390	EPSD	COSMIC	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	O75030	MITF	P49841	GSK3B	S511	S511I	511	Missense	central	0	yes	6.054	0.000	EPSD	COSMIC	6.007	Loss
CMGC_GSK_GSK3B_ST	O75030	MITF	P49841	GSK3B	S512	S512I	512	Missense	central	0	yes	9.465	0.000	EPSD	COSMIC	6.007	Loss
CMGC_GSK_GSK3B_ST	O75030	MITF	P49841	GSK3B	S512	A507T	507	Missense	distal	-5	no	9.465	9.477	EPSD	COSMIC	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	O75030	MITF	P49841	GSK3B	S512	R513W	513	Missense	proximal	1	no	9.465	9.683	EPSD	COSMIC	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	O75030	MITF	P49841	GSK3B	S512	S511I	511	Missense	proximal	-1	no	9.465	9.316	EPSD	COSMIC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	O75030	MITF	P49841	GSK3B	S518	S512I	512	Missense	distal	-6	no	6.269	6.206	EPSD	COSMIC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	O75030	MITF	P49841	GSK3B	S518	R513W	513	Missense	distal	-5	no	6.269	6.012	EPSD	COSMIC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	O75030	MITF	P49841	GSK3B	S518	T522M	522	Missense	distal	4	no	6.269	4.903	EPSD	COSMIC	6.007	Loss
CMGC_GSK_GSK3B_ST	O75030	MITF	P49841	GSK3B	S518	S518I	518	Missense	central	0	yes	6.269	0.000	EPSD	COSMIC	6.007	Loss
CMGC_GSK_GSK3B_ST	O75030	MITF	P49841	GSK3B	S518	S511I	511	Missense	distal	-7	no	6.269	6.296	EPSD	COSMIC	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	P48436	SOX9	P49841	GSK3B	S19	A21V	21	Missense	proximal	2	no	9.328	9.051	EPSD	COSMIC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	P48436	SOX9	P49841	GSK3B	S19	Q14R	14	Missense	distal	-5	no	9.328	9.882	EPSD	COSMIC	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	P48436	SOX9	P49841	GSK3B	S19	P24T	24	Missense	distal	5	no	9.328	8.351	EPSD	COSMIC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	P48436	SOX9	P49841	GSK3B	S19	P22L	22	Missense	distal	3	no	9.328	9.010	EPSD	COSMIC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	P48436	SOX9	P49841	GSK3B	S19	A21T	21	Missense	proximal	2	no	9.328	9.447	EPSD	COSMIC	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	P48436	SOX9	P49841	GSK3B	S19	E13A	13	Missense	distal	-6	no	9.328	9.400	EPSD	COSMIC	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	P48436	SOX9	P49841	GSK3B	S19	M26V	26	Missense	distal	7	no	9.328	9.385	EPSD	COSMIC	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	P48436	SOX9	P49841	GSK3B	S23	A21V	21	Missense	proximal	-2	no	9.576	9.878	EPSD	COSMIC	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	P48436	SOX9	P49841	GSK3B	S23	E28D	28	Missense	distal	5	no	9.576	9.373	EPSD	COSMIC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	P48436	SOX9	P49841	GSK3B	S23	P24T	24	Missense	proximal	1	no	9.576	6.385	EPSD	COSMIC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	P48436	SOX9	P49841	GSK3B	S23	P22L	22	Missense	proximal	-1	no	9.576	9.445	EPSD	COSMIC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	P48436	SOX9	P49841	GSK3B	S23	A21T	21	Missense	proximal	-2	no	9.576	9.938	EPSD	COSMIC	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	P48436	SOX9	P49841	GSK3B	S23	M26V	26	Missense	distal	3	no	9.576	9.559	EPSD	COSMIC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	P48436	SOX9	P49841	GSK3B	S33	S39C	39	Missense	distal	6	no	8.960	8.947	EPSD	COSMIC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	P48436	SOX9	P49841	GSK3B	S33	E28D	28	Missense	distal	-5	no	8.960	8.801	EPSD	COSMIC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	P48436	SOX9	P49841	GSK3B	S33	P34T	34	Missense	proximal	1	no	8.960	5.769	EPSD	COSMIC	6.007	Loss
CMGC_GSK_GSK3B_ST	P48436	SOX9	P49841	GSK3B	S33	S33L	33	Missense	central	0	yes	8.960	0.000	EPSD	COSMIC	6.007	Loss
CMGC_GSK_GSK3B_ST	P48436	SOX9	P49841	GSK3B	S33	A31G	31	Missense	proximal	-2	no	8.960	9.177	EPSD	COSMIC	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	P48436	SOX9	P49841	GSK3B	S33	G32C	32	Missense	proximal	-1	no	8.960	8.917	EPSD	COSMIC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	P48436	SOX9	P49841	GSK3B	S33	P36Q	36	Missense	distal	3	no	8.960	8.904	EPSD	COSMIC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	P48436	SOX9	P49841	GSK3B	S37	S39C	39	Missense	proximal	2	no	8.222	7.730	EPSD	COSMIC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	P48436	SOX9	P49841	GSK3B	S37	S41L	41	Missense	distal	4	no	8.222	5.505	EPSD	COSMIC	6.007	Loss
CMGC_GSK_GSK3B_ST	P48436	SOX9	P49841	GSK3B	S37	D42Y	42	Missense	distal	5	no	8.222	7.117	EPSD	COSMIC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	P48436	SOX9	P49841	GSK3B	S37	P34T	34	Missense	distal	-3	no	8.222	8.364	EPSD	COSMIC	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	P48436	SOX9	P49841	GSK3B	S37	S33L	33	Missense	distal	-4	no	8.222	6.872	EPSD	COSMIC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	P48436	SOX9	P49841	GSK3B	S37	A31G	31	Missense	distal	-6	no	8.222	8.228	EPSD	COSMIC	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	P48436	SOX9	P49841	GSK3B	S37	G32C	32	Missense	distal	-5	no	8.222	8.276	EPSD	COSMIC	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	P48436	SOX9	P49841	GSK3B	S37	P36Q	36	Missense	proximal	-1	no	8.222	8.060	EPSD	COSMIC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	P48436	SOX9	P49841	GSK3B	S149	P153S	153	Missense	distal	4	no	3.108	6.079	EPSD	COSMIC	6.007	Gain
CMGC_GSK_GSK3B_ST	P48436	SOX9	P49841	GSK3B	S211	P212S	212	Missense	proximal	1	no	8.253	4.408	EPSD	COSMIC	6.007	Loss
CMGC_GSK_GSK3B_ST	P48436	SOX9	P49841	GSK3B	S215	E220D	220	Missense	distal	5	no	7.687	7.485	EPSD	COSMIC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	P48436	SOX9	P49841	GSK3B	S215	P212S	212	Missense	distal	-3	no	7.687	7.804	EPSD	COSMIC	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	P48436	SOX9	P49841	GSK3B	S219	E220D	220	Missense	proximal	1	no	6.894	7.625	EPSD	COSMIC	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	P48436	SOX9	P49841	GSK3B	S219	P212S	212	Missense	distal	-7	no	6.894	6.896	EPSD	COSMIC	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	P48436	SOX9	P49841	GSK3B	S223	H227Y	227	Missense	distal	4	no	8.263	8.506	EPSD	COSMIC	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	P48436	SOX9	P49841	GSK3B	S223	S228L	228	Missense	distal	5	no	8.263	7.937	EPSD	COSMIC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	P48436	SOX9	P49841	GSK3B	S223	G229R	229	Missense	distal	6	no	8.263	8.262	EPSD	COSMIC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	P48436	SOX9	P49841	GSK3B	S223	E220D	220	Missense	distal	-3	no	8.263	8.296	EPSD	COSMIC	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	P48436	SOX9	P49841	GSK3B	T236	P235R	235	Missense	proximal	-1	no	8.814	8.620	PhosphoSitePlus	COSMIC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	P48436	SOX9	P49841	GSK3B	T236	P235T	235	Missense	proximal	-1	no	8.814	8.683	PhosphoSitePlus	COSMIC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	P48436	SOX9	P49841	GSK3B	T236	P237L	237	Missense	proximal	1	no	8.814	5.953	PhosphoSitePlus	COSMIC	6.007	Loss
CMGC_GSK_GSK3B_ST	P48436	SOX9	P49841	GSK3B	T236	G229R	229	Missense	distal	-7	no	8.814	8.834	PhosphoSitePlus	COSMIC	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	P48436	SOX9	P49841	GSK3B	T236	G233S	233	Missense	distal	-3	no	8.814	8.818	PhosphoSitePlus	COSMIC	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	P48436	SOX9	P49841	GSK3B	T239	P235R	235	Missense	distal	-4	no	6.312	5.689	EPSD	COSMIC	6.007	Loss
CMGC_GSK_GSK3B_ST	P48436	SOX9	P49841	GSK3B	T239	P235T	235	Missense	distal	-4	no	6.312	6.540	EPSD	COSMIC	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	P48436	SOX9	P49841	GSK3B	T239	P237L	237	Missense	proximal	-2	no	6.312	5.982	EPSD	COSMIC	6.007	Loss
CMGC_GSK_GSK3B_ST	P48436	SOX9	P49841	GSK3B	T239	G233S	233	Missense	distal	-6	no	6.312	6.296	EPSD	COSMIC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	P48436	SOX9	P49841	GSK3B	T240	P235R	235	Missense	distal	-5	no	5.470	6.324	EPSD	COSMIC	6.007	Gain
CMGC_GSK_GSK3B_ST	P48436	SOX9	P49841	GSK3B	S488	D482Y	482	Missense	distal	-6	no	6.552	6.491	EPSD	COSMIC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	P48436	SOX9	P49841	GSK3B	S488	V486A	486	Missense	proximal	-2	no	6.552	6.250	EPSD	COSMIC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	P48436	SOX9	P49841	GSK3B	S488	V486D	486	Missense	proximal	-2	no	6.552	6.569	EPSD	COSMIC	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	P48436	SOX9	P49841	GSK3B	S488	P495L	495	Missense	distal	7	no	6.552	6.601	EPSD	COSMIC	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	P48436	SOX9	P49841	GSK3B	S488	P487L	487	Missense	proximal	-1	no	6.552	6.421	EPSD	COSMIC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	P48436	SOX9	P49841	GSK3B	S488	H493Q	493	Missense	distal	5	no	6.552	7.202	EPSD	COSMIC	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	P48436	SOX9	P49841	GSK3B	S494	E499K	499	Missense	distal	5	no	7.457	6.590	EPSD	COSMIC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	P48436	SOX9	P49841	GSK3B	S494	P495L	495	Missense	proximal	1	no	7.457	4.596	EPSD	COSMIC	6.007	Loss
CMGC_GSK_GSK3B_ST	P48436	SOX9	P49841	GSK3B	S494	P487L	487	Missense	distal	-7	no	7.457	7.458	EPSD	COSMIC	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	P48436	SOX9	P49841	GSK3B	S494	H493Q	493	Missense	proximal	-1	no	7.457	7.402	EPSD	COSMIC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	P06401	PGR	P49841	GSK3B	S20	A15V	15	Missense	distal	-5	no	5.950	6.252	EPSD	COSMIC	6.007	Gain
CMGC_GSK_GSK3B_ST	P06401	PGR	P49841	GSK3B	S20	G24V	24	Missense	distal	4	no	5.950	6.803	EPSD	COSMIC	6.007	Gain
CMGC_GSK_GSK3B_ST	P06401	PGR	P49841	GSK3B	S102	G97E	97	Missense	distal	-5	no	7.295	7.259	EPSD	COSMIC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	P06401	PGR	P49841	GSK3B	S102	P103L	103	Missense	proximal	1	no	7.295	4.434	EPSD	COSMIC	6.007	Loss
CMGC_GSK_GSK3B_ST	P06401	PGR	P49841	GSK3B	S102	S99N	99	Missense	distal	-3	no	7.295	7.200	EPSD	COSMIC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	P06401	PGR	P49841	GSK3B	S102	P103H	103	Missense	proximal	1	no	7.295	3.594	EPSD	COSMIC	6.007	Loss
CMGC_GSK_GSK3B_ST	P06401	PGR	P49841	GSK3B	S162	S168F	168	Missense	distal	6	no	11.146	11.134	EPSD	COSMIC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	P06401	PGR	P49841	GSK3B	S162	R167W	167	Missense	distal	5	no	11.146	9.845	EPSD	COSMIC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	P06401	PGR	P49841	GSK3B	S162	M165I	165	Missense	distal	3	no	11.146	10.917	EPSD	COSMIC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	P06401	PGR	P49841	GSK3B	S213	A208D	208	Missense	distal	-5	no	6.936	6.931	EPSD	COSMIC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	P06401	PGR	P49841	GSK3B	S213	V219F	219	Missense	distal	6	no	6.936	6.934	EPSD	COSMIC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	P06401	PGR	P49841	GSK3B	S273	E271K	271	Missense	proximal	-2	no	6.161	6.129	EPSD	COSMIC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	P06401	PGR	P49841	GSK3B	S273	A277V	277	Missense	distal	4	no	6.161	6.182	EPSD	COSMIC	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	P06401	PGR	P49841	GSK3B	S273	A266T	266	Missense	distal	-7	no	6.161	6.165	EPSD	COSMIC;GDSC	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	P06401	PGR	P49841	GSK3B	S294	V300M	300	Missense	distal	6	no	9.431	9.436	EPSD	COSMIC	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	P06401	PGR	P49841	GSK3B	S294	A287V	287	Missense	distal	-7	no	9.431	9.430	EPSD	COSMIC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	P06401	PGR	P49841	GSK3B	S294	A290E	290	Missense	distal	-4	no	9.431	9.994	EPSD	COSMIC	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	P06401	PGR	P49841	GSK3B	S294	P291S	291	Missense	distal	-3	no	9.431	9.548	EPSD	COSMIC	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	P06401	PGR	P49841	GSK3B	S345	C347G	347	Missense	proximal	2	no	9.402	9.636	EPSD	COSMIC	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	P06401	PGR	P49841	GSK3B	S345	S344T	344	Missense	proximal	-1	no	9.402	9.327	EPSD	COSMIC;GDSC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	P06401	PGR	P49841	GSK3B	S345	S349L	349	Missense	distal	4	no	9.402	6.685	EPSD	COSMIC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	P06401	PGR	P49841	GSK3B	S345	P352L	352	Missense	distal	7	no	9.402	9.451	EPSD	COSMIC	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	P06401	PGR	P49841	GSK3B	T351	C347G	347	Missense	distal	-4	no	7.159	8.845	EPSD	COSMIC	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	P06401	PGR	P49841	GSK3B	T351	S344T	344	Missense	distal	-7	no	7.159	7.186	EPSD	COSMIC;GDSC	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	P06401	PGR	P49841	GSK3B	T351	S349L	349	Missense	proximal	-2	no	7.159	7.085	EPSD	COSMIC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	P06401	PGR	P49841	GSK3B	T351	V353A	353	Missense	proximal	2	no	7.159	7.436	EPSD	COSMIC	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	P06401	PGR	P49841	GSK3B	T351	D357N	357	Missense	distal	6	no	7.159	7.160	EPSD	COSMIC	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	P06401	PGR	P49841	GSK3B	T351	P352L	352	Missense	proximal	1	no	7.159	4.298	EPSD	COSMIC	6.007	Loss
CMGC_GSK_GSK3B_ST	P06401	PGR	P49841	GSK3B	S554	P547L	547	Missense	distal	-7	no	10.722	10.724	EPSD	COSMIC	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	P06401	PGR	P49841	GSK3B	S666	Q667H	667	Missense	proximal	1	no	6.451	6.019	EPSD	COSMIC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	P06401	PGR	P49841	GSK3B	S666	E665K	665	Missense	proximal	-1	no	6.451	6.518	EPSD	COSMIC	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	O75952	CABYR	P49841	GSK3B	T75	G73E	73	Missense	proximal	-2	no	7.069	7.084	EPSD	COSMIC	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	O75952	CABYR	P49841	GSK3B	T120	A127T	127	Missense	distal	7	no	7.066	6.659	EPSD	COSMIC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	O75952	CABYR	P49841	GSK3B	S142	A145T	145	Missense	distal	3	no	7.933	8.237	EPSD	COSMIC;GDSC;CCLE	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	O75952	CABYR	P49841	GSK3B	S142	L140I	140	Missense	proximal	-2	no	7.933	7.996	EPSD	COSMIC	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	O75952	CABYR	P49841	GSK3B	T146	A145T	145	Missense	proximal	-1	no	9.852	9.932	EPSD	COSMIC;GDSC;CCLE	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	O75952	CABYR	P49841	GSK3B	T146	L140I	140	Missense	distal	-6	no	9.852	9.791	EPSD	COSMIC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	O75952	CABYR	P49841	GSK3B	T150	A145T	145	Missense	distal	-5	no	7.591	7.603	EPSD	COSMIC;GDSC;CCLE	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	O75952	CABYR	P49841	GSK3B	T151	A145T	145	Missense	distal	-6	no	11.855	11.786	PhosphoSitePlus;EPSD	COSMIC;GDSC;CCLE	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	O75952	CABYR	P49841	GSK3B	S339	S346F	346	Missense	distal	7	no	10.741	10.819	EPSD	COSMIC	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	O75952	CABYR	P49841	GSK3B	S339	E335D	335	Missense	distal	-4	no	10.741	10.738	EPSD	COSMIC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	O75952	CABYR	P49841	GSK3B	S343	S346F	346	Missense	distal	3	no	7.555	7.344	EPSD	COSMIC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	O75952	CABYR	P49841	GSK3B	S343	E349D	349	Missense	distal	6	no	7.555	7.554	EPSD	COSMIC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	O75952	CABYR	P49841	GSK3B	T463	H460Y	460	Missense	distal	-3	no	6.095	6.123	EPSD	COSMIC	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	O75952	CABYR	P49841	GSK3B	S464	H460Y	460	Missense	distal	-4	no	5.936	6.223	EPSD	COSMIC	6.007	Gain
CMGC_GSK_GSK3B_ST	Q01518	CAP1	P49841	GSK3B	S34	R29S	29	Missense	distal	-5	no	9.154	8.457	EPSD	COSMIC;GDSC;CCLE	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	Q01518	CAP1	P49841	GSK3B	S222	A226S	226	Missense	distal	4	no	5.153	7.564	EPSD	COSMIC;GDSC;CCLE	6.007	Gain
CMGC_GSK_GSK3B_ST	Q01518	CAP1	P49841	GSK3B	S308	S310P	310	Missense	proximal	2	no	6.186	6.630	EPSD;PhosphoSitePlus	COSMIC;GDSC	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	Q01518	CAP1	P49841	GSK3B	S308	R313G	313	Missense	distal	5	no	6.186	5.912	EPSD;PhosphoSitePlus	COSMIC	6.007	Loss
CMGC_GSK_GSK3B_ST	Q01518	CAP1	P49841	GSK3B	S308	S301Y	301	Missense	distal	-7	no	6.186	6.214	EPSD;PhosphoSitePlus	COSMIC	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	Q01518	CAP1	P49841	GSK3B	S308	P309L	309	Missense	proximal	1	no	6.186	3.325	EPSD;PhosphoSitePlus	COSMIC	6.007	Loss
CMGC_GSK_GSK3B_ST	Q01518	CAP1	P49841	GSK3B	S310	S310P	310	Missense	central	0	yes	7.057	0.000	PhosphoSitePlus;EPSD	COSMIC;GDSC	6.007	Loss
CMGC_GSK_GSK3B_ST	Q01518	CAP1	P49841	GSK3B	S310	R313G	313	Missense	distal	3	no	7.057	7.472	PhosphoSitePlus;EPSD	COSMIC	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	Q01518	CAP1	P49841	GSK3B	S310	P309L	309	Missense	proximal	-1	no	7.057	6.926	PhosphoSitePlus;EPSD	COSMIC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	P04150	NR3C1	P49841	GSK3B	T8	R11I	11	Missense	distal	3	no	6.709	6.660	EPSD	COSMIC;GDSC;CCLE	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	P04150	NR3C1	P49841	GSK3B	T8	P15L	15	Missense	distal	7	no	6.709	6.758	EPSD	COSMIC	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	P04150	NR3C1	P49841	GSK3B	S45	A49V	49	Missense	distal	4	no	6.427	6.449	EPSD	COSMIC	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	P04150	NR3C1	P49841	GSK3B	S79	A81V	81	Missense	proximal	2	no	6.608	6.331	EPSD	COSMIC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	P04150	NR3C1	P49841	GSK3B	S79	D77Y	77	Missense	proximal	-2	no	6.608	6.305	EPSD	COSMIC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	P04150	NR3C1	P49841	GSK3B	S141	E137D	137	Missense	distal	-4	no	6.393	6.390	EPSD	COSMIC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	P04150	NR3C1	P49841	GSK3B	S141	A146V	146	Missense	distal	5	no	6.393	5.967	EPSD	COSMIC;GDSC;CCLE	6.007	Loss
CMGC_GSK_GSK3B_ST	P04150	NR3C1	P49841	GSK3B	S141	A146S	146	Missense	distal	5	no	6.393	6.468	EPSD	COSMIC;GDSC;CCLE	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	P04150	NR3C1	P49841	GSK3B	S141	S142L	142	Missense	proximal	1	no	6.393	7.377	EPSD	COSMIC	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	P04150	NR3C1	P49841	GSK3B	S203	T208A	208	Missense	distal	5	no	9.879	9.827	EPSD	COSMIC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	P04150	NR3C1	P49841	GSK3B	S211	T208A	208	Missense	distal	-3	no	9.880	9.876	EPSD	COSMIC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	P04150	NR3C1	P49841	GSK3B	S267	P268L	268	Missense	proximal	1	no	6.655	3.795	EPSD	COSMIC	6.007	Loss
CMGC_GSK_GSK3B_ST	P04150	NR3C1	P49841	GSK3B	S395	Y393H	393	Missense	proximal	-2	no	7.593	7.807	EPSD	COSMIC	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	P04150	NR3C1	P49841	GSK3B	S404	P405T	405	Missense	proximal	1	no	11.548	8.357	PhosphoSitePlus	COSMIC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	P04150	NR3C1	P49841	GSK3B	S407	P405T	405	Missense	proximal	-2	no	6.996	6.767	EPSD	COSMIC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	P04150	NR3C1	P49841	GSK3B	S408	G415V	415	Missense	distal	7	no	6.121	6.527	EPSD	COSMIC	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	P04150	NR3C1	P49841	GSK3B	S408	P405T	405	Missense	distal	-3	no	6.121	6.263	EPSD	COSMIC	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	P04150	NR3C1	P49841	GSK3B	S409	G415V	415	Missense	distal	6	no	6.328	6.321	EPSD	COSMIC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	P04150	NR3C1	P49841	GSK3B	S409	P405T	405	Missense	distal	-4	no	6.328	6.556	EPSD	COSMIC	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	P04150	NR3C1	P49841	GSK3B	S410	P405T	405	Missense	distal	-5	no	5.994	6.440	EPSD	COSMIC	6.007	Gain
CMGC_GSK_GSK3B_ST	Q9NP62	GCM1	P49841	GSK3B	S182	S186R	186	Missense	distal	4	no	6.817	3.779	EPSD	COSMIC	6.007	Loss
CMGC_GSK_GSK3B_ST	Q9NP62	GCM1	P49841	GSK3B	S322	P317L	317	Missense	distal	-5	no	7.677	7.943	PhosphoSitePlus	COSMIC	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	Q9NP62	GCM1	P49841	GSK3B	S322	P329S	329	Missense	distal	7	no	7.677	7.741	PhosphoSitePlus	COSMIC	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	Q9NP62	GCM1	P49841	GSK3B	S326	P329S	329	Missense	distal	3	no	6.523	6.505	EPSD	COSMIC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	Q00613	HSF1	P49841	GSK3B	S123	D129G	129	Missense	distal	6	no	8.317	8.321	EPSD	COSMIC	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	Q00613	HSF1	P49841	GSK3B	S123	T120A	120	Missense	distal	-3	no	8.317	8.313	EPSD	COSMIC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	Q00613	HSF1	P49841	GSK3B	T124	D129G	129	Missense	distal	5	no	6.591	6.527	EPSD	COSMIC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	Q00613	HSF1	P49841	GSK3B	T124	T120A	120	Missense	distal	-4	no	6.591	5.767	EPSD	COSMIC	6.007	Loss
CMGC_GSK_GSK3B_ST	Q00613	HSF1	P49841	GSK3B	S237	G236S	236	Missense	proximal	-1	no	6.380	6.373	EPSD	COSMIC;CCLE	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	Q00613	HSF1	P49841	GSK3B	S237	S237L	237	Missense	central	0	yes	6.380	0.000	EPSD	COSMIC	6.007	Loss
CMGC_GSK_GSK3B_ST	Q00613	HSF1	P49841	GSK3B	S237	P239H	239	Missense	proximal	2	no	6.380	5.611	EPSD	COSMIC	6.007	Loss
CMGC_GSK_GSK3B_ST	Q00613	HSF1	P49841	GSK3B	S237	S244F	244	Missense	distal	7	no	6.380	6.457	EPSD	COSMIC	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	Q00613	HSF1	P49841	GSK3B	S244	P239H	239	Missense	distal	-5	no	9.276	9.599	EPSD	COSMIC	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	Q00613	HSF1	P49841	GSK3B	S244	S244F	244	Missense	central	0	yes	9.276	0.000	EPSD	COSMIC	6.007	Loss
CMGC_GSK_GSK3B_ST	Q00613	HSF1	P49841	GSK3B	S275	S279F	279	Missense	distal	4	no	10.301	6.687	EPSD	COSMIC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	Q00613	HSF1	P49841	GSK3B	S275	P280L	280	Missense	distal	5	no	10.301	9.020	EPSD	COSMIC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	Q00613	HSF1	P49841	GSK3B	S275	I268V	268	Missense	distal	-7	no	10.301	10.295	EPSD	COSMIC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	Q00613	HSF1	P49841	GSK3B	S275	G281S	281	Missense	distal	6	no	10.301	10.304	EPSD	COSMIC	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	Q00613	HSF1	P49841	GSK3B	S279	S279F	279	Missense	central	0	yes	9.764	0.000	EPSD	COSMIC	6.007	Loss
CMGC_GSK_GSK3B_ST	Q00613	HSF1	P49841	GSK3B	S279	P280L	280	Missense	proximal	1	no	9.764	6.904	EPSD	COSMIC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	Q00613	HSF1	P49841	GSK3B	S279	G281S	281	Missense	proximal	2	no	9.764	10.023	EPSD	COSMIC	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	Q00613	HSF1	P49841	GSK3B	S279	S283N	283	Missense	distal	4	no	9.764	6.154	EPSD	COSMIC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	Q00613	HSF1	P49841	GSK3B	S292	R287K	287	Missense	distal	-5	no	7.295	6.797	EPSD	COSMIC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	Q00613	HSF1	P49841	GSK3B	S303	S303G	303	Missense	central	0	yes	13.157	0.000	PhosphoSitePlus	COSMIC	6.007	Loss
CMGC_GSK_GSK3B_ST	Q00613	HSF1	P49841	GSK3B	S303	P304L	304	Missense	proximal	1	no	13.157	10.296	PhosphoSitePlus	COSMIC;GDSC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	Q00613	HSF1	P49841	GSK3B	S303	R309G	309	Missense	distal	6	no	13.157	13.158	PhosphoSitePlus	COSMIC	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	Q00613	HSF1	P49841	GSK3B	S307	S303G	303	Missense	distal	-4	no	8.879	8.451	EPSD	COSMIC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	Q00613	HSF1	P49841	GSK3B	S307	P304L	304	Missense	distal	-3	no	8.879	9.005	EPSD	COSMIC;GDSC	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	Q00613	HSF1	P49841	GSK3B	S307	R309G	309	Missense	proximal	2	no	8.879	8.602	EPSD	COSMIC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	Q00613	HSF1	P49841	GSK3B	S314	R309G	309	Missense	distal	-5	no	6.674	6.443	EPSD	COSMIC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	Q00613	HSF1	P49841	GSK3B	S314	P318T	318	Missense	distal	4	no	6.674	8.776	EPSD	COSMIC	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	Q00613	HSF1	P49841	GSK3B	S326	L330V	330	Missense	distal	4	no	6.572	6.900	EPSD	COSMIC	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	Q00613	HSF1	P49841	GSK3B	S326	P327Q	327	Missense	proximal	1	no	6.572	3.304	EPSD	COSMIC	6.007	Loss
CMGC_GSK_GSK3B_ST	Q00613	HSF1	P49841	GSK3B	S344	T349M	349	Missense	distal	5	no	6.021	5.905	EPSD	COSMIC	6.007	Loss
CMGC_GSK_GSK3B_ST	Q00613	HSF1	P49841	GSK3B	S344	P342T	342	Missense	proximal	-2	no	6.021	5.792	EPSD	COSMIC	6.007	Loss
CMGC_GSK_GSK3B_ST	Q00613	HSF1	P49841	GSK3B	S344	S344C	344	Missense	central	0	yes	6.021	0.000	EPSD	COSMIC	6.007	Loss
CMGC_GSK_GSK3B_ST	Q00613	HSF1	P49841	GSK3B	S363	S363P	363	Missense	central	0	yes	11.390	0.000	EPSD	COSMIC	6.007	Loss
CMGC_GSK_GSK3B_ST	Q00613	HSF1	P49841	GSK3B	S363	P365Q	365	Missense	proximal	2	no	11.390	11.169	EPSD	COSMIC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	Q00613	HSF1	P49841	GSK3B	S363	D356N	356	Missense	distal	-7	no	11.390	11.393	EPSD	COSMIC	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	Q00613	HSF1	P49841	GSK3B	S363	P365T	365	Missense	proximal	2	no	11.390	11.072	EPSD	COSMIC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	Q00613	HSF1	P49841	GSK3B	S363	E358K	358	Missense	distal	-5	no	11.390	11.159	EPSD	COSMIC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	Q00613	HSF1	P49841	GSK3B	S363	P365L	365	Missense	proximal	2	no	11.390	11.006	EPSD	COSMIC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	Q00613	HSF1	P49841	GSK3B	S419	L417Q	417	Missense	proximal	-2	no	7.800	7.829	EPSD	COSMIC	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	Q00613	HSF1	P49841	GSK3B	S419	V422M	422	Missense	distal	3	no	7.800	7.817	EPSD	COSMIC	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	Q00613	HSF1	P49841	GSK3B	S419	S419N	419	Missense	central	0	yes	7.800	0.000	EPSD	COSMIC	6.007	Loss
CMGC_GSK_GSK3B_ST	Q00613	HSF1	P49841	GSK3B	S444	E447K	447	Missense	distal	3	no	8.709	8.602	EPSD	COSMIC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	Q00613	HSF1	P49841	GSK3B	S457	P452H	452	Missense	distal	-5	no	6.497	6.821	EPSD	COSMIC	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	Q00613	HSF1	P49841	GSK3B	S458	P452H	452	Missense	distal	-6	no	6.430	6.376	EPSD	COSMIC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	Q9HB09	BCL2L12	P49841	GSK3B	T117	S121R	121	Missense	distal	4	no	12.033	8.995	EPSD	COSMIC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	Q9HB09	BCL2L12	P49841	GSK3B	T117	P122H	122	Missense	distal	5	no	12.033	10.406	EPSD	COSMIC;GDSC;CCLE	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	Q9HB09	BCL2L12	P49841	GSK3B	S121	E125K	125	Missense	distal	4	no	8.641	7.459	EPSD	COSMIC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	Q9HB09	BCL2L12	P49841	GSK3B	S121	T128A	128	Missense	distal	7	no	8.641	9.048	EPSD	COSMIC	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	Q9HB09	BCL2L12	P49841	GSK3B	S121	S121R	121	Missense	central	0	yes	8.641	0.000	EPSD	COSMIC	6.007	Loss
CMGC_GSK_GSK3B_ST	Q9HB09	BCL2L12	P49841	GSK3B	S121	P122H	122	Missense	proximal	1	no	8.641	4.941	EPSD	COSMIC;GDSC;CCLE	6.007	Loss
CMGC_GSK_GSK3B_ST	Q9HB09	BCL2L12	P49841	GSK3B	S156	S151F	151	Missense	distal	-5	no	6.428	6.988	PhosphoSitePlus	COSMIC	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	Q9HB09	BCL2L12	P49841	GSK3B	S156	P161H	161	Missense	distal	5	no	6.428	4.801	PhosphoSitePlus	COSMIC	6.007	Loss
CMGC_GSK_GSK3B_ST	Q9HB09	BCL2L12	P49841	GSK3B	T171	P172T	172	Missense	proximal	1	no	7.344	4.153	EPSD	COSMIC	6.007	Loss
CMGC_GSK_GSK3B_ST	Q9HB09	BCL2L12	P49841	GSK3B	S192	Q199P	199	Missense	distal	7	no	8.491	8.338	EPSD	COSMIC;GDSC;CCLE	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	Q9HB09	BCL2L12	P49841	GSK3B	S192	P193T	193	Missense	proximal	1	no	8.491	5.300	EPSD	COSMIC	6.007	Loss
CMGC_GSK_GSK3B_ST	Q9HB09	BCL2L12	P49841	GSK3B	S192	L198V	198	Missense	distal	6	no	8.491	8.486	EPSD	COSMIC;CCLE	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	Q9HB09	BCL2L12	P49841	GSK3B	S192	L198S	198	Missense	distal	6	no	8.491	8.496	EPSD	COSMIC	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	Q9HB09	BCL2L12	P49841	GSK3B	S195	Q199P	199	Missense	distal	4	no	7.349	7.941	EPSD	COSMIC;GDSC;CCLE	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	Q9HB09	BCL2L12	P49841	GSK3B	S195	P193T	193	Missense	proximal	-2	no	7.349	7.120	EPSD	COSMIC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	Q9HB09	BCL2L12	P49841	GSK3B	S195	L198V	198	Missense	distal	3	no	7.349	7.441	EPSD	COSMIC;CCLE	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	Q9HB09	BCL2L12	P49841	GSK3B	S195	L198S	198	Missense	distal	3	no	7.349	7.649	EPSD	COSMIC	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	Q9HB09	BCL2L12	P49841	GSK3B	S273	P271S	271	Missense	proximal	-2	no	8.561	8.305	EPSD	COSMIC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	Q9HB09	BCL2L12	P49841	GSK3B	S273	E275K	275	Missense	proximal	2	no	8.561	8.601	EPSD	COSMIC	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	Q9HB09	BCL2L12	P49841	GSK3B	S273	P272S	272	Missense	proximal	-1	no	8.561	8.505	EPSD	COSMIC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	Q9HB09	BCL2L12	P49841	GSK3B	S273	R279H	279	Missense	distal	6	no	8.561	8.556	EPSD	COSMIC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	O75581	LRP6	P49841	GSK3B	T420	L417S	417	Missense	distal	-3	no	6.201	6.192	EPSD	COSMIC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	O75581	LRP6	P49841	GSK3B	T420	R426Q	426	Missense	distal	6	no	6.201	6.202	EPSD	COSMIC	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	O75581	LRP6	P49841	GSK3B	T420	W419R	419	Missense	proximal	-1	no	6.201	6.089	EPSD	COSMIC;GDSC;CCLE	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	O75581	LRP6	P49841	GSK3B	T1001	P1008S	1008	Missense	distal	7	no	8.027	8.091	EPSD	COSMIC	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	O75581	LRP6	P49841	GSK3B	T1001	P1008L	1008	Missense	distal	7	no	8.027	8.076	EPSD	COSMIC	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	O75581	LRP6	P49841	GSK3B	T1001	V1007A	1007	Missense	distal	6	no	8.027	8.036	EPSD	COSMIC	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	O75581	LRP6	P49841	GSK3B	T1001	Q998R	998	Missense	distal	-3	no	8.027	8.166	EPSD	COSMIC;GDSC	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	O75581	LRP6	P49841	GSK3B	T1001	G999S	999	Missense	proximal	-2	no	8.027	8.145	EPSD	COSMIC;GDSC	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	O75581	LRP6	P49841	GSK3B	T1001	D995H	995	Missense	distal	-6	no	8.027	8.019	EPSD	COSMIC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	O75581	LRP6	P49841	GSK3B	S1440	S1447N	1447	Missense	distal	7	no	6.938	7.061	EPSD	COSMIC	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	O75581	LRP6	P49841	GSK3B	S1444	S1447N	1447	Missense	distal	3	no	6.997	7.045	EPSD	COSMIC	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	O75581	LRP6	P49841	GSK3B	S1470	A1463V	1463	Missense	distal	-7	no	6.323	6.322	EPSD	COSMIC;GDSC;CCLE	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	O75581	LRP6	P49841	GSK3B	S1470	H1464Y	1464	Missense	distal	-6	no	6.323	6.271	EPSD	COSMIC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	O75581	LRP6	P49841	GSK3B	S1470	S1469A	1469	Missense	proximal	-1	no	6.323	6.169	EPSD	COSMIC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	O75581	LRP6	P49841	GSK3B	S1473	S1469A	1469	Missense	distal	-4	no	7.015	5.855	EPSD	COSMIC	6.007	Loss
CMGC_GSK_GSK3B_ST	O75581	LRP6	P49841	GSK3B	S1475	S1469A	1469	Missense	distal	-6	no	6.420	6.431	EPSD	COSMIC	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	O75581	LRP6	P49841	GSK3B	S1490	S1490F	1490	Missense	central	0	yes	9.049	0.000	PhosphoSitePlus	COSMIC	6.007	Loss
CMGC_GSK_GSK3B_ST	O75581	LRP6	P49841	GSK3B	S1490	S1496L	1496	Missense	distal	6	no	9.049	9.044	PhosphoSitePlus	COSMIC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	O75581	LRP6	P49841	GSK3B	S1506	N1507K	1507	Missense	proximal	1	no	4.304	6.278	EPSD	COSMIC	6.007	Gain
CMGC_GSK_GSK3B_ST	O75581	LRP6	P49841	GSK3B	S1508	S1508R	1508	Missense	central	0	yes	6.755	0.000	EPSD	COSMIC	6.007	Loss
CMGC_GSK_GSK3B_ST	O75581	LRP6	P49841	GSK3B	S1508	S1514A	1514	Missense	distal	6	no	6.755	6.753	EPSD	COSMIC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	O75581	LRP6	P49841	GSK3B	S1508	F1502C	1502	Missense	distal	-6	no	6.755	6.797	EPSD	COSMIC	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	O75581	LRP6	P49841	GSK3B	S1508	N1507K	1507	Missense	proximal	-1	no	6.755	6.748	EPSD	COSMIC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	O75581	LRP6	P49841	GSK3B	T1530	P1528H	1528	Missense	proximal	-2	no	7.392	7.031	EPSD	COSMIC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	O75581	LRP6	P49841	GSK3B	T1530	R1523Q	1523	Missense	distal	-7	no	7.392	7.389	EPSD	COSMIC;GDSC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	O75581	LRP6	P49841	GSK3B	S1539	P1543S	1543	Missense	distal	4	no	3.738	6.709	EPSD	COSMIC	6.007	Gain
CMGC_GSK_GSK3B_ST	O75581	LRP6	P49841	GSK3B	S1544	R1545L	1545	Missense	proximal	1	no	7.238	6.698	EPSD	COSMIC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	O75581	LRP6	P49841	GSK3B	S1544	A1542G	1542	Missense	proximal	-2	no	7.238	7.455	EPSD	COSMIC	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	O75581	LRP6	P49841	GSK3B	S1544	P1543S	1543	Missense	proximal	-1	no	7.238	7.182	EPSD	COSMIC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	O75581	LRP6	P49841	GSK3B	T1572	P1571S	1571	Missense	proximal	-1	no	6.098	6.042	EPSD	COSMIC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	O75581	LRP6	P49841	GSK3B	S1575	E1581Q	1581	Missense	distal	6	no	7.459	7.461	EPSD	COSMIC	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	O75581	LRP6	P49841	GSK3B	S1575	P1571S	1571	Missense	distal	-4	no	7.459	8.022	EPSD	COSMIC	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	O75581	LRP6	P49841	GSK3B	S1586	P1589R	1589	Missense	distal	3	no	7.141	6.752	EPSD	COSMIC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	O75581	LRP6	P49841	GSK3B	S1586	E1581Q	1581	Missense	distal	-5	no	7.141	6.853	EPSD	COSMIC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	O75581	LRP6	P49841	GSK3B	S1590	P1589R	1589	Missense	proximal	-1	no	9.819	9.626	EPSD	COSMIC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	O75581	LRP6	P49841	GSK3B	S1607	H1600Q	1600	Missense	distal	-7	no	8.861	8.858	EPSD	COSMIC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	O75581	LRP6	P49841	GSK3B	S1607	P1604L	1604	Missense	distal	-3	no	8.861	8.987	EPSD	COSMIC	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	Q9H0B6	KLC2	P49841	GSK3B	S151	A150T	150	Missense	proximal	-1	no	6.767	6.847	EPSD	COSMIC;GDSC;CCLE	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	Q9H0B6	KLC2	P49841	GSK3B	S175	Q174K	174	Missense	proximal	-1	no	10.231	10.393	EPSD	COSMIC	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	Q9H0B6	KLC2	P49841	GSK3B	S179	Q174K	174	Missense	distal	-5	no	7.675	7.732	EPSD	COSMIC	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	Q9H0B6	KLC2	P49841	GSK3B	S436	A440S	440	Missense	distal	4	no	5.225	7.637	EPSD	COSMIC	6.007	Gain
CMGC_GSK_GSK3B_ST	Q9H0B6	KLC2	P49841	GSK3B	T450	V443I	443	Missense	distal	-7	no	6.253	6.259	EPSD	COSMIC	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	Q9H0B6	KLC2	P49841	GSK3B	T450	S445I	445	Missense	distal	-5	no	6.253	6.725	EPSD	COSMIC	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	Q9H0B6	KLC2	P49841	GSK3B	S539	S539F	539	Missense	central	0	yes	7.780	0.000	EPSD	COSMIC	6.007	Loss
CMGC_GSK_GSK3B_ST	Q9H0B6	KLC2	P49841	GSK3B	S539	G536D	536	Missense	distal	-3	no	7.780	7.830	EPSD	COSMIC	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	Q9H0B6	KLC2	P49841	GSK3B	S611	R616Q	616	Missense	distal	5	no	6.365	6.026	EPSD	COSMIC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	Q9H0B6	KLC2	P49841	GSK3B	S615	L620M	620	Missense	distal	5	no	9.158	9.346	EPSD	COSMIC	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	Q9H0B6	KLC2	P49841	GSK3B	S615	R616Q	616	Missense	proximal	1	no	9.158	8.210	EPSD	COSMIC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	Q6U7Q0	ZNF322	P49841	GSK3B	S391	K386T	386	Missense	distal	-5	no	10.846	10.935	PhosphoSitePlus	COSMIC	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	Q6R327	RICTOR	P49841	GSK3B	T31	P27S	27	Missense	distal	-4	no	6.382	6.945	EPSD	COSMIC	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	Q6R327	RICTOR	P49841	GSK3B	T31	D29E	29	Missense	proximal	-2	no	6.382	6.295	EPSD	COSMIC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	Q6R327	RICTOR	P49841	GSK3B	S221	A226V	226	Missense	distal	5	no	7.476	7.050	EPSD	COSMIC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	Q6R327	RICTOR	P49841	GSK3B	S221	I228F	228	Missense	distal	7	no	7.476	7.218	EPSD	COSMIC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	Q6R327	RICTOR	P49841	GSK3B	S221	R222Q	222	Missense	proximal	1	no	7.476	6.528	EPSD	COSMIC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	Q6R327	RICTOR	P49841	GSK3B	S221	S221N	221	Missense	central	0	yes	7.476	0.000	EPSD	COSMIC	6.007	Loss
CMGC_GSK_GSK3B_ST	Q6R327	RICTOR	P49841	GSK3B	S221	V215L	215	Missense	distal	-6	no	7.476	7.542	EPSD	COSMIC;GDSC;CCLE	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	Q6R327	RICTOR	P49841	GSK3B	S265	D259G	259	Missense	distal	-6	no	7.362	7.403	EPSD	COSMIC	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	Q6R327	RICTOR	P49841	GSK3B	S265	H261N	261	Missense	distal	-4	no	7.362	7.153	EPSD	COSMIC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	Q6R327	RICTOR	P49841	GSK3B	S1026	T1029A	1029	Missense	distal	3	no	6.716	6.412	EPSD	COSMIC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	Q6R327	RICTOR	P49841	GSK3B	S1031	T1029A	1029	Missense	proximal	-2	no	8.808	8.446	EPSD	COSMIC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	Q6R327	RICTOR	P49841	GSK3B	S1039	P1041S	1041	Missense	proximal	2	no	7.585	7.141	EPSD	COSMIC;GDSC;CCLE	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	Q6R327	RICTOR	P49841	GSK3B	S1122	P1115A	1115	Missense	distal	-7	no	6.052	6.076	EPSD	COSMIC	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	Q6R327	RICTOR	P49841	GSK3B	S1144	D1140E	1140	Missense	distal	-4	no	6.854	6.857	EPSD	COSMIC	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	Q6R327	RICTOR	P49841	GSK3B	S1144	S1151C	1151	Missense	distal	7	no	6.854	7.246	EPSD	COSMIC	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	Q6R327	RICTOR	P49841	GSK3B	S1144	D1140Y	1140	Missense	distal	-4	no	6.854	6.654	EPSD	COSMIC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	Q6R327	RICTOR	P49841	GSK3B	T1148	S1151C	1151	Missense	distal	3	no	7.539	7.324	EPSD	COSMIC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	Q6R327	RICTOR	P49841	GSK3B	T1152	S1151C	1151	Missense	proximal	-1	no	7.207	7.171	EPSD	COSMIC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	Q6R327	RICTOR	P49841	GSK3B	T1175	E1180D	1180	Missense	distal	5	no	7.162	6.960	EPSD	COSMIC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	Q6R327	RICTOR	P49841	GSK3B	T1175	E1170Q	1170	Missense	distal	-5	no	7.162	6.874	EPSD	COSMIC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	Q6R327	RICTOR	P49841	GSK3B	T1175	D1171Y	1171	Missense	distal	-4	no	7.162	6.962	EPSD	COSMIC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	Q6R327	RICTOR	P49841	GSK3B	T1175	E1180A	1180	Missense	distal	5	no	7.162	6.779	EPSD	COSMIC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	Q6R327	RICTOR	P49841	GSK3B	T1175	E1180K	1180	Missense	distal	5	no	7.162	6.295	EPSD	COSMIC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	Q6R327	RICTOR	P49841	GSK3B	T1175	I1178T	1178	Missense	distal	3	no	7.162	7.550	EPSD	COSMIC	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	Q6R327	RICTOR	P49841	GSK3B	T1175	T1172A	1172	Missense	distal	-3	no	7.162	7.158	EPSD	COSMIC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	Q6R327	RICTOR	P49841	GSK3B	S1231	P1236A	1236	Missense	distal	5	no	9.116	8.087	EPSD	COSMIC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	Q6R327	RICTOR	P49841	GSK3B	S1235	P1236A	1236	Missense	proximal	1	no	9.254	5.522	EPSD;PhosphoSitePlus	COSMIC	6.007	Loss
CMGC_GSK_GSK3B_ST	Q6R327	RICTOR	P49841	GSK3B	S1235	E1239D	1239	Missense	distal	4	no	9.254	8.851	EPSD;PhosphoSitePlus	COSMIC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	Q6R327	RICTOR	P49841	GSK3B	S1278	N1283S	1283	Missense	distal	5	no	6.547	6.867	EPSD	COSMIC	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	Q6R327	RICTOR	P49841	GSK3B	S1278	L1279P	1279	Missense	proximal	1	no	6.547	9.407	EPSD	COSMIC;CCLE	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	Q6R327	RICTOR	P49841	GSK3B	S1278	S1278F	1278	Missense	central	0	yes	6.547	0.000	EPSD	COSMIC	6.007	Loss
CMGC_GSK_GSK3B_ST	Q6R327	RICTOR	P49841	GSK3B	S1280	L1279P	1279	Missense	proximal	-1	no	5.876	6.007	EPSD	COSMIC;CCLE	6.007	Gain
CMGC_GSK_GSK3B_ST	Q6R327	RICTOR	P49841	GSK3B	S1284	N1283S	1283	Missense	proximal	-1	no	6.416	6.354	EPSD	COSMIC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	Q6R327	RICTOR	P49841	GSK3B	S1284	L1279P	1279	Missense	distal	-5	no	6.416	6.150	EPSD	COSMIC;CCLE	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	Q6R327	RICTOR	P49841	GSK3B	S1284	S1278F	1278	Missense	distal	-6	no	6.416	6.362	EPSD	COSMIC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	Q6R327	RICTOR	P49841	GSK3B	S1293	P1297S	1297	Missense	distal	4	no	3.301	6.272	EPSD	COSMIC	6.007	Gain
CMGC_GSK_GSK3B_ST	Q6R327	RICTOR	P49841	GSK3B	S1320	C1317F	1317	Missense	distal	-3	no	8.162	8.126	EPSD	COSMIC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	Q6R327	RICTOR	P49841	GSK3B	S1320	S1323I	1323	Missense	distal	3	no	8.162	7.742	EPSD	COSMIC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	Q6R327	RICTOR	P49841	GSK3B	T1361	P1354L	1354	Missense	distal	-7	no	6.612	6.613	EPSD	COSMIC	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	Q6R327	RICTOR	P49841	GSK3B	T1361	F1360C	1360	Missense	proximal	-1	no	6.612	6.706	EPSD	COSMIC	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	Q6R327	RICTOR	P49841	GSK3B	T1376	R1379K	1379	Missense	distal	3	no	6.930	7.174	EPSD	COSMIC	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	Q6R327	RICTOR	P49841	GSK3B	T1376	E1372K	1372	Missense	distal	-4	no	6.930	6.662	EPSD	COSMIC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	Q6R327	RICTOR	P49841	GSK3B	T1376	R1379S	1379	Missense	distal	3	no	6.930	7.301	EPSD	COSMIC	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	Q6R327	RICTOR	P49841	GSK3B	T1376	F1380L	1380	Missense	distal	4	no	6.930	7.826	EPSD	COSMIC	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	Q6R327	RICTOR	P49841	GSK3B	S1411	R1410W	1410	Missense	proximal	-1	no	7.061	7.173	EPSD	COSMIC	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	Q6R327	RICTOR	P49841	GSK3B	S1411	S1406F	1406	Missense	distal	-5	no	7.061	7.621	EPSD	COSMIC	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	Q6R327	RICTOR	P49841	GSK3B	S1411	R1410Q	1410	Missense	proximal	-1	no	7.061	7.092	EPSD	COSMIC	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	Q6R327	RICTOR	P49841	GSK3B	S1581	S1581F	1581	Missense	central	0	yes	7.230	0.000	EPSD	COSMIC	6.007	Loss
CMGC_GSK_GSK3B_ST	Q6R327	RICTOR	P49841	GSK3B	S1585	S1581F	1581	Missense	distal	-4	no	6.811	5.657	EPSD	COSMIC	6.007	Loss
CMGC_GSK_GSK3B_ST	Q6R327	RICTOR	P49841	GSK3B	S1585	S1591N	1591	Missense	distal	6	no	6.811	6.804	EPSD	COSMIC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	Q6R327	RICTOR	P49841	GSK3B	S1587	S1581F	1581	Missense	distal	-6	no	6.424	6.371	EPSD	COSMIC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	Q6R327	RICTOR	P49841	GSK3B	S1587	S1591N	1591	Missense	distal	4	no	6.424	2.814	EPSD	COSMIC	6.007	Loss
CMGC_GSK_GSK3B_ST	Q6R327	RICTOR	P49841	GSK3B	S1588	S1581F	1581	Missense	distal	-7	no	7.334	7.344	EPSD	COSMIC	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	Q6R327	RICTOR	P49841	GSK3B	S1588	S1591N	1591	Missense	distal	3	no	7.334	7.382	EPSD	COSMIC	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	Q6R327	RICTOR	P49841	GSK3B	T1695	T1695I	1695	Missense	central	0	yes	8.632	0.000	PhosphoSitePlus;EPSD	COSMIC	6.007	Loss
CMGC_GSK_GSK3B_ST	Q6R327	RICTOR	P49841	GSK3B	T1695	T1695A	1695	Missense	central	0	yes	8.632	0.000	PhosphoSitePlus;EPSD	COSMIC;CCLE	6.007	Loss
CMGC_GSK_GSK3B_ST	P01106	MYC	P49841	GSK3B	T58	P57S	57	Missense	proximal	-1	no	12.188	12.132	EPSD;PhosphoSitePlus	COSMIC;CCLE	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	P01106	MYC	P49841	GSK3B	T58	S62P	62	Missense	distal	4	no	12.188	9.217	EPSD;PhosphoSitePlus	COSMIC;CCLE	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	P01106	MYC	P49841	GSK3B	T58	P59L	59	Missense	proximal	1	no	12.188	9.328	EPSD;PhosphoSitePlus	COSMIC;CCLE	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	P01106	MYC	P49841	GSK3B	T58	T58N	58	Missense	central	0	yes	12.188	0.000	EPSD;PhosphoSitePlus	COSMIC;CCLE	6.007	Loss
CMGC_GSK_GSK3B_ST	P01106	MYC	P49841	GSK3B	T58	P60H	60	Missense	proximal	2	no	12.188	11.419	EPSD;PhosphoSitePlus	COSMIC;CCLE	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	P01106	MYC	P49841	GSK3B	T58	P63L	63	Missense	distal	5	no	12.188	10.908	EPSD;PhosphoSitePlus	COSMIC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	P01106	MYC	P49841	GSK3B	T58	P63H	63	Missense	distal	5	no	12.188	10.561	EPSD;PhosphoSitePlus	COSMIC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	P01106	MYC	P49841	GSK3B	T58	T58A	58	Missense	central	0	yes	12.188	0.000	EPSD;PhosphoSitePlus	COSMIC;CCLE	6.007	Loss
CMGC_GSK_GSK3B_ST	P01106	MYC	P49841	GSK3B	T58	P59A	59	Missense	proximal	1	no	12.188	8.456	EPSD;PhosphoSitePlus	COSMIC;CCLE	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	P01106	MYC	P49841	GSK3B	T58	P59R	59	Missense	proximal	1	no	12.188	9.868	EPSD;PhosphoSitePlus	COSMIC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	P01106	MYC	P49841	GSK3B	T58	P60A	60	Missense	proximal	2	no	12.188	11.752	EPSD;PhosphoSitePlus	COSMIC;CCLE	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	P01106	MYC	P49841	GSK3B	T58	P57T	57	Missense	proximal	-1	no	12.188	12.057	EPSD;PhosphoSitePlus	COSMIC;CCLE	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	P01106	MYC	P49841	GSK3B	T58	P59S	59	Missense	proximal	1	no	12.188	8.343	EPSD;PhosphoSitePlus	COSMIC;CCLE	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	P01106	MYC	P49841	GSK3B	T58	S62F	62	Missense	distal	4	no	12.188	8.574	EPSD;PhosphoSitePlus	COSMIC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	P01106	MYC	P49841	GSK3B	T58	T58I	58	Missense	central	0	yes	12.188	0.000	EPSD;PhosphoSitePlus	COSMIC;CCLE	6.007	Loss
CMGC_GSK_GSK3B_ST	P01106	MYC	P49841	GSK3B	T58	K51N	51	Missense	distal	-7	no	12.188	12.173	EPSD;PhosphoSitePlus	COSMIC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	P01106	MYC	P49841	GSK3B	T58	T58P	58	Missense	central	0	yes	12.188	0.000	EPSD;PhosphoSitePlus	COSMIC	6.007	Loss
CMGC_GSK_GSK3B_ST	P01106	MYC	P49841	GSK3B	T58	S64R	64	Missense	distal	6	no	12.188	12.184	EPSD;PhosphoSitePlus	COSMIC;CCLE	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	P01106	MYC	P49841	GSK3B	T58	P57L	57	Missense	proximal	-1	no	12.188	12.057	EPSD;PhosphoSitePlus	COSMIC;CCLE	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	P01106	MYC	P49841	GSK3B	T58	P63S	63	Missense	distal	5	no	12.188	11.234	EPSD;PhosphoSitePlus	COSMIC;CCLE	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	P01106	MYC	P49841	GSK3B	T58	P57F	57	Missense	proximal	-1	no	12.188	12.001	EPSD;PhosphoSitePlus	COSMIC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	P01106	MYC	P49841	GSK3B	T58	P59Q	59	Missense	proximal	1	no	12.188	8.920	EPSD;PhosphoSitePlus	COSMIC;CCLE	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	P01106	MYC	P49841	GSK3B	T58	P59T	59	Missense	proximal	1	no	12.188	8.997	EPSD;PhosphoSitePlus	COSMIC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	P01106	MYC	P49841	GSK3B	T58	P60S	60	Missense	proximal	2	no	12.188	11.744	EPSD;PhosphoSitePlus	COSMIC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	P01106	MYC	P49841	GSK3B	T58	P63A	63	Missense	distal	5	no	12.188	11.159	EPSD;PhosphoSitePlus	COSMIC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	P01106	MYC	P49841	GSK3B	T58	S64N	64	Missense	distal	6	no	12.188	12.182	EPSD;PhosphoSitePlus	COSMIC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	P01106	MYC	P49841	GSK3B	T58	P60L	60	Missense	proximal	2	no	12.188	11.804	EPSD;PhosphoSitePlus	COSMIC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	P01106	MYC	P49841	GSK3B	T58	P57A	57	Missense	proximal	-1	no	12.188	11.977	EPSD;PhosphoSitePlus	COSMIC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	P01106	MYC	P49841	GSK3B	T58	L56V	56	Missense	proximal	-2	no	12.188	12.230	EPSD;PhosphoSitePlus	COSMIC	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	P01106	MYC	P49841	GSK3B	T58	P63R	63	Missense	distal	5	no	12.188	11.551	EPSD;PhosphoSitePlus	COSMIC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	P01106	MYC	P49841	GSK3B	T58	L56M	56	Missense	proximal	-2	no	12.188	11.931	EPSD;PhosphoSitePlus	COSMIC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	P01106	MYC	P49841	GSK3B	T58	P63T	63	Missense	distal	5	no	12.188	11.212	EPSD;PhosphoSitePlus	COSMIC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	P01106	MYC	P49841	GSK3B	T58	S62A	62	Missense	distal	4	no	12.188	9.777	EPSD;PhosphoSitePlus	COSMIC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	P01106	MYC	P49841	GSK3B	T58	P57R	57	Missense	proximal	-1	no	12.188	11.995	EPSD;PhosphoSitePlus	COSMIC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	P01106	MYC	P49841	GSK3B	T58	P60T	60	Missense	proximal	2	no	12.188	11.871	EPSD;PhosphoSitePlus	COSMIC;CCLE	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	P01106	MYC	P49841	GSK3B	T58	E54V	54	Missense	distal	-4	no	12.188	11.552	EPSD;PhosphoSitePlus	COSMIC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	P01106	MYC	P49841	GSK3B	T58	S64T	64	Missense	distal	6	no	12.188	12.190	EPSD;PhosphoSitePlus	COSMIC	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	P01106	MYC	P49841	GSK3B	T58	R65C	65	Missense	distal	7	no	12.188	12.143	EPSD;PhosphoSitePlus	COSMIC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	P01106	MYC	P49841	GSK3B	T58	L55P	55	Missense	distal	-3	no	12.188	12.062	EPSD;PhosphoSitePlus	COSMIC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	P01106	MYC	P49841	GSK3B	T58	L55M	55	Missense	distal	-3	no	12.188	12.151	EPSD;PhosphoSitePlus	COSMIC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	P01106	MYC	P49841	GSK3B	T58	E54A	54	Missense	distal	-4	no	12.188	11.626	EPSD;PhosphoSitePlus	COSMIC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	P01106	MYC	P49841	GSK3B	S62	P57S	57	Missense	distal	-5	no	6.697	6.854	PhosphoSitePlus;EPSD	COSMIC;CCLE	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	P01106	MYC	P49841	GSK3B	S62	S62P	62	Missense	central	0	yes	6.697	0.000	PhosphoSitePlus;EPSD	COSMIC;CCLE	6.007	Loss
CMGC_GSK_GSK3B_ST	P01106	MYC	P49841	GSK3B	S62	P59L	59	Missense	distal	-3	no	6.697	6.824	PhosphoSitePlus;EPSD	COSMIC;CCLE	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	P01106	MYC	P49841	GSK3B	S62	T58N	58	Missense	distal	-4	no	6.697	5.735	PhosphoSitePlus;EPSD	COSMIC;CCLE	6.007	Loss
CMGC_GSK_GSK3B_ST	P01106	MYC	P49841	GSK3B	S62	P60H	60	Missense	proximal	-2	no	6.697	6.336	PhosphoSitePlus;EPSD	COSMIC;CCLE	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	P01106	MYC	P49841	GSK3B	S62	P63L	63	Missense	proximal	1	no	6.697	3.837	PhosphoSitePlus;EPSD	COSMIC	6.007	Loss
CMGC_GSK_GSK3B_ST	P01106	MYC	P49841	GSK3B	S62	P63H	63	Missense	proximal	1	no	6.697	2.997	PhosphoSitePlus;EPSD	COSMIC	6.007	Loss
CMGC_GSK_GSK3B_ST	P01106	MYC	P49841	GSK3B	S62	T58A	58	Missense	distal	-4	no	6.697	5.873	PhosphoSitePlus;EPSD	COSMIC;CCLE	6.007	Loss
CMGC_GSK_GSK3B_ST	P01106	MYC	P49841	GSK3B	S62	P59A	59	Missense	distal	-3	no	6.697	6.835	PhosphoSitePlus;EPSD	COSMIC;CCLE	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	P01106	MYC	P49841	GSK3B	S62	P59R	59	Missense	distal	-3	no	6.697	6.983	PhosphoSitePlus;EPSD	COSMIC	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	P01106	MYC	P49841	GSK3B	S62	P60A	60	Missense	proximal	-2	no	6.697	6.106	PhosphoSitePlus;EPSD	COSMIC;CCLE	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	P01106	MYC	P49841	GSK3B	S62	P57T	57	Missense	distal	-5	no	6.697	7.143	PhosphoSitePlus;EPSD	COSMIC;CCLE	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	P01106	MYC	P49841	GSK3B	S62	P59S	59	Missense	distal	-3	no	6.697	6.814	PhosphoSitePlus;EPSD	COSMIC;CCLE	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	P01106	MYC	P49841	GSK3B	S62	S62F	62	Missense	central	0	yes	6.697	0.000	PhosphoSitePlus;EPSD	COSMIC	6.007	Loss
CMGC_GSK_GSK3B_ST	P01106	MYC	P49841	GSK3B	S62	T58I	58	Missense	distal	-4	no	6.697	4.550	PhosphoSitePlus;EPSD	COSMIC;CCLE	6.007	Loss
CMGC_GSK_GSK3B_ST	P01106	MYC	P49841	GSK3B	S62	T58P	58	Missense	distal	-4	no	6.697	6.469	PhosphoSitePlus;EPSD	COSMIC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	P01106	MYC	P49841	GSK3B	S62	S64R	64	Missense	proximal	2	no	6.697	6.716	PhosphoSitePlus;EPSD	COSMIC;CCLE	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	P01106	MYC	P49841	GSK3B	S62	P57L	57	Missense	distal	-5	no	6.697	6.963	PhosphoSitePlus;EPSD	COSMIC;CCLE	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	P01106	MYC	P49841	GSK3B	S62	P63S	63	Missense	proximal	1	no	6.697	2.852	PhosphoSitePlus;EPSD	COSMIC;CCLE	6.007	Loss
CMGC_GSK_GSK3B_ST	P01106	MYC	P49841	GSK3B	S62	R66H	66	Missense	distal	4	no	6.697	5.979	PhosphoSitePlus;EPSD	COSMIC	6.007	Loss
CMGC_GSK_GSK3B_ST	P01106	MYC	P49841	GSK3B	S62	P57F	57	Missense	distal	-5	no	6.697	7.414	PhosphoSitePlus;EPSD	COSMIC	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	P01106	MYC	P49841	GSK3B	S62	P59Q	59	Missense	distal	-3	no	6.697	6.844	PhosphoSitePlus;EPSD	COSMIC;CCLE	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	P01106	MYC	P49841	GSK3B	S62	P59T	59	Missense	distal	-3	no	6.697	6.839	PhosphoSitePlus;EPSD	COSMIC	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	P01106	MYC	P49841	GSK3B	S62	P60S	60	Missense	proximal	-2	no	6.697	6.441	PhosphoSitePlus;EPSD	COSMIC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	P01106	MYC	P49841	GSK3B	S62	P63A	63	Missense	proximal	1	no	6.697	2.965	PhosphoSitePlus;EPSD	COSMIC	6.007	Loss
CMGC_GSK_GSK3B_ST	P01106	MYC	P49841	GSK3B	S62	S64N	64	Missense	proximal	2	no	6.697	6.165	PhosphoSitePlus;EPSD	COSMIC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	P01106	MYC	P49841	GSK3B	S62	P60L	60	Missense	proximal	-2	no	6.697	6.367	PhosphoSitePlus;EPSD	COSMIC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	P01106	MYC	P49841	GSK3B	S62	P57A	57	Missense	distal	-5	no	6.697	7.131	PhosphoSitePlus;EPSD	COSMIC	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	P01106	MYC	P49841	GSK3B	S62	L56V	56	Missense	distal	-6	no	6.697	6.631	PhosphoSitePlus;EPSD	COSMIC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	P01106	MYC	P49841	GSK3B	S62	P63R	63	Missense	proximal	1	no	6.697	4.377	PhosphoSitePlus;EPSD	COSMIC	6.007	Loss
CMGC_GSK_GSK3B_ST	P01106	MYC	P49841	GSK3B	S62	L56M	56	Missense	distal	-6	no	6.697	6.646	PhosphoSitePlus;EPSD	COSMIC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	P01106	MYC	P49841	GSK3B	S62	L69V	69	Missense	distal	7	no	6.697	7.137	PhosphoSitePlus;EPSD	COSMIC	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	P01106	MYC	P49841	GSK3B	S62	P63T	63	Missense	proximal	1	no	6.697	3.506	PhosphoSitePlus;EPSD	COSMIC	6.007	Loss
CMGC_GSK_GSK3B_ST	P01106	MYC	P49841	GSK3B	S62	S67F	67	Missense	distal	5	no	6.697	6.030	PhosphoSitePlus;EPSD	COSMIC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	P01106	MYC	P49841	GSK3B	S62	S62A	62	Missense	central	0	yes	6.697	0.000	PhosphoSitePlus;EPSD	COSMIC	6.007	Loss
CMGC_GSK_GSK3B_ST	P01106	MYC	P49841	GSK3B	S62	P57R	57	Missense	distal	-5	no	6.697	7.551	PhosphoSitePlus;EPSD	COSMIC	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	P01106	MYC	P49841	GSK3B	S62	L69P	69	Missense	distal	7	no	6.697	6.648	PhosphoSitePlus;EPSD	COSMIC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	P01106	MYC	P49841	GSK3B	S62	P60T	60	Missense	proximal	-2	no	6.697	6.468	PhosphoSitePlus;EPSD	COSMIC;CCLE	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	P01106	MYC	P49841	GSK3B	S62	L69F	69	Missense	distal	7	no	6.697	6.789	PhosphoSitePlus;EPSD	COSMIC	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	P01106	MYC	P49841	GSK3B	S62	S64T	64	Missense	proximal	2	no	6.697	6.824	PhosphoSitePlus;EPSD	COSMIC	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	P01106	MYC	P49841	GSK3B	S62	R65C	65	Missense	distal	3	no	6.697	6.853	PhosphoSitePlus;EPSD	COSMIC	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	P01106	MYC	P49841	GSK3B	S62	L55P	55	Missense	distal	-7	no	6.697	6.696	PhosphoSitePlus;EPSD	COSMIC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	P01106	MYC	P49841	GSK3B	S62	L55M	55	Missense	distal	-7	no	6.697	6.718	PhosphoSitePlus;EPSD	COSMIC	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	P01106	MYC	P49841	GSK3B	S67	S62P	62	Missense	distal	-5	no	7.689	7.532	EPSD	COSMIC;CCLE	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	P01106	MYC	P49841	GSK3B	S67	P60H	60	Missense	distal	-7	no	7.689	7.709	EPSD	COSMIC;CCLE	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	P01106	MYC	P49841	GSK3B	S67	P63L	63	Missense	distal	-4	no	7.689	6.902	EPSD	COSMIC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	P01106	MYC	P49841	GSK3B	S67	P63H	63	Missense	distal	-4	no	7.689	7.164	EPSD	COSMIC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	P01106	MYC	P49841	GSK3B	S67	P60A	60	Missense	distal	-7	no	7.689	7.713	EPSD	COSMIC;CCLE	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	P01106	MYC	P49841	GSK3B	S67	S62F	62	Missense	distal	-5	no	7.689	8.249	EPSD	COSMIC	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	P01106	MYC	P49841	GSK3B	S67	C70R	70	Missense	distal	3	no	7.689	7.534	EPSD	COSMIC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	P01106	MYC	P49841	GSK3B	S67	S64R	64	Missense	distal	-3	no	7.689	7.858	EPSD	COSMIC;CCLE	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	P01106	MYC	P49841	GSK3B	S67	P63S	63	Missense	distal	-4	no	7.689	8.252	EPSD	COSMIC;CCLE	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	P01106	MYC	P49841	GSK3B	S67	R66H	66	Missense	proximal	-1	no	7.689	7.775	EPSD	COSMIC	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	P01106	MYC	P49841	GSK3B	S67	P60S	60	Missense	distal	-7	no	7.689	7.691	EPSD	COSMIC	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	P01106	MYC	P49841	GSK3B	S67	S71L	71	Missense	distal	4	no	7.689	4.971	EPSD	COSMIC	6.007	Loss
CMGC_GSK_GSK3B_ST	P01106	MYC	P49841	GSK3B	S67	P63A	63	Missense	distal	-4	no	7.689	7.093	EPSD	COSMIC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	P01106	MYC	P49841	GSK3B	S67	S64N	64	Missense	distal	-3	no	7.689	7.594	EPSD	COSMIC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	P01106	MYC	P49841	GSK3B	S67	P60L	60	Missense	distal	-7	no	7.689	7.691	EPSD	COSMIC	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	P01106	MYC	P49841	GSK3B	S67	Y74N	74	Missense	distal	7	no	7.689	7.370	EPSD	COSMIC;CCLE	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	P01106	MYC	P49841	GSK3B	S67	P63R	63	Missense	distal	-4	no	7.689	7.065	EPSD	COSMIC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	P01106	MYC	P49841	GSK3B	S67	L69V	69	Missense	proximal	2	no	7.689	7.360	EPSD	COSMIC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	P01106	MYC	P49841	GSK3B	S67	P63T	63	Missense	distal	-4	no	7.689	7.917	EPSD	COSMIC	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	P01106	MYC	P49841	GSK3B	S67	Y74H	74	Missense	distal	7	no	7.689	7.873	EPSD	COSMIC	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	P01106	MYC	P49841	GSK3B	S67	S67F	67	Missense	central	0	yes	7.689	0.000	EPSD	COSMIC	6.007	Loss
CMGC_GSK_GSK3B_ST	P01106	MYC	P49841	GSK3B	S67	S62A	62	Missense	distal	-5	no	7.689	7.966	EPSD	COSMIC	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	P01106	MYC	P49841	GSK3B	S67	L69P	69	Missense	proximal	2	no	7.689	8.073	EPSD	COSMIC	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	P01106	MYC	P49841	GSK3B	S67	C70W	70	Missense	distal	3	no	7.689	7.792	EPSD	COSMIC	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	P01106	MYC	P49841	GSK3B	S67	P60T	60	Missense	distal	-7	no	7.689	7.718	EPSD	COSMIC;CCLE	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	P01106	MYC	P49841	GSK3B	S67	S71W	71	Missense	distal	4	no	7.689	3.740	EPSD	COSMIC	6.007	Loss
CMGC_GSK_GSK3B_ST	P01106	MYC	P49841	GSK3B	S67	L69F	69	Missense	proximal	2	no	7.689	7.284	EPSD	COSMIC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	P01106	MYC	P49841	GSK3B	S67	S73P	73	Missense	distal	6	no	7.689	7.691	EPSD	COSMIC	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	P01106	MYC	P49841	GSK3B	S67	S64T	64	Missense	distal	-3	no	7.689	7.714	EPSD	COSMIC	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	P01106	MYC	P49841	GSK3B	S67	R65C	65	Missense	proximal	-2	no	7.689	7.493	EPSD	COSMIC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	P01106	MYC	P49841	GSK3B	S67	P72F	72	Missense	distal	5	no	7.689	6.068	EPSD	COSMIC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	P01106	MYC	P49841	GSK3B	S67	P72R	72	Missense	distal	5	no	7.689	7.051	EPSD	COSMIC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	P01106	MYC	P49841	GSK3B	S71	C70R	70	Missense	proximal	-1	no	8.090	7.989	EPSD	COSMIC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	P01106	MYC	P49841	GSK3B	S71	S64R	64	Missense	distal	-7	no	8.090	8.108	EPSD	COSMIC;CCLE	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	P01106	MYC	P49841	GSK3B	S71	R66H	66	Missense	distal	-5	no	8.090	7.559	EPSD	COSMIC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	P01106	MYC	P49841	GSK3B	S71	A76V	76	Missense	distal	5	no	8.090	7.663	EPSD	COSMIC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	P01106	MYC	P49841	GSK3B	S71	V77I	77	Missense	distal	6	no	8.090	8.099	EPSD	COSMIC;CCLE	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	P01106	MYC	P49841	GSK3B	S71	S71L	71	Missense	central	0	yes	8.090	0.000	EPSD	COSMIC	6.007	Loss
CMGC_GSK_GSK3B_ST	P01106	MYC	P49841	GSK3B	S71	S64N	64	Missense	distal	-7	no	8.090	8.096	EPSD	COSMIC	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	P01106	MYC	P49841	GSK3B	S71	Y74N	74	Missense	distal	3	no	8.090	8.560	EPSD	COSMIC;CCLE	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	P01106	MYC	P49841	GSK3B	S71	L69V	69	Missense	proximal	-2	no	8.090	8.131	EPSD	COSMIC	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	P01106	MYC	P49841	GSK3B	S71	V77G	77	Missense	distal	6	no	8.090	8.097	EPSD	COSMIC	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	P01106	MYC	P49841	GSK3B	S71	Y74H	74	Missense	distal	3	no	8.090	8.483	EPSD	COSMIC	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	P01106	MYC	P49841	GSK3B	S71	S67F	67	Missense	distal	-4	no	8.090	6.936	EPSD	COSMIC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	P01106	MYC	P49841	GSK3B	S71	V75I	75	Missense	distal	4	no	8.090	7.158	EPSD	COSMIC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	P01106	MYC	P49841	GSK3B	S71	L69P	69	Missense	proximal	-2	no	8.090	8.420	EPSD	COSMIC	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	P01106	MYC	P49841	GSK3B	S71	C70W	70	Missense	proximal	-1	no	8.090	8.100	EPSD	COSMIC	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	P01106	MYC	P49841	GSK3B	S71	S71W	71	Missense	central	0	yes	8.090	0.000	EPSD	COSMIC	6.007	Loss
CMGC_GSK_GSK3B_ST	P01106	MYC	P49841	GSK3B	S71	L69F	69	Missense	proximal	-2	no	8.090	7.833	EPSD	COSMIC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	P01106	MYC	P49841	GSK3B	S71	S73P	73	Missense	proximal	2	no	8.090	8.534	EPSD	COSMIC	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	P01106	MYC	P49841	GSK3B	S71	S64T	64	Missense	distal	-7	no	8.090	8.117	EPSD	COSMIC	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	P01106	MYC	P49841	GSK3B	S71	R65C	65	Missense	distal	-6	no	8.090	8.135	EPSD	COSMIC	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	P01106	MYC	P49841	GSK3B	S71	P72F	72	Missense	proximal	1	no	8.090	3.859	EPSD	COSMIC	6.007	Loss
CMGC_GSK_GSK3B_ST	P01106	MYC	P49841	GSK3B	S71	P72R	72	Missense	proximal	1	no	8.090	5.770	EPSD	COSMIC	6.007	Loss
CMGC_GSK_GSK3B_ST	P01106	MYC	P49841	GSK3B	T78	F80L	80	Missense	proximal	2	no	5.606	6.010	EPSD	COSMIC	6.007	Gain
CMGC_GSK_GSK3B_ST	P01106	MYC	P49841	GSK3B	S151	A155S	155	Missense	distal	4	no	4.133	6.545	EPSD	COSMIC	6.007	Gain
CMGC_GSK_GSK3B_ST	P01106	MYC	P49841	GSK3B	S161	K157T	157	Missense	distal	-4	no	9.025	9.554	EPSD	COSMIC	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	P01106	MYC	P49841	GSK3B	S161	A155S	155	Missense	distal	-6	no	9.025	9.014	EPSD	COSMIC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	P01106	MYC	P49841	GSK3B	S161	K157N	157	Missense	distal	-4	no	9.025	8.592	EPSD	COSMIC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	P01106	MYC	P49841	GSK3B	S161	A155T	155	Missense	distal	-6	no	9.025	8.956	EPSD	COSMIC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	P01106	MYC	P49841	GSK3B	S161	N163K	163	Missense	proximal	2	no	9.025	9.510	EPSD	COSMIC	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	P01106	MYC	P49841	GSK3B	S161	P162R	162	Missense	proximal	1	no	9.025	6.705	EPSD	COSMIC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	P01106	MYC	P49841	GSK3B	S161	A154T	154	Missense	distal	-7	no	9.025	9.030	EPSD	COSMIC	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	P01106	MYC	P49841	GSK3B	S161	G160D	160	Missense	proximal	-1	no	9.025	8.958	EPSD	COSMIC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	P01106	MYC	P49841	GSK3B	S161	S159N	159	Missense	proximal	-2	no	9.025	8.796	EPSD	COSMIC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	P01106	MYC	P49841	GSK3B	S161	A165S	165	Missense	distal	4	no	9.025	11.437	EPSD	COSMIC	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	P01106	MYC	P49841	GSK3B	S161	A165T	165	Missense	distal	4	no	9.025	10.568	EPSD	COSMIC	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	P01106	MYC	P49841	GSK3B	S161	S159T	159	Missense	proximal	-2	no	9.025	9.052	EPSD	COSMIC	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	P01106	MYC	P49841	GSK3B	S161	D158G	158	Missense	distal	-3	no	9.025	8.975	EPSD	COSMIC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	P01106	MYC	P49841	GSK3B	S161	R166H	166	Missense	distal	5	no	9.025	8.036	EPSD	COSMIC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	P01106	MYC	P49841	GSK3B	S161	S161N	161	Missense	central	0	yes	9.025	0.000	EPSD	COSMIC	6.007	Loss
CMGC_GSK_GSK3B_ST	P01106	MYC	P49841	GSK3B	S161	R156G	156	Missense	distal	-5	no	9.025	8.794	EPSD	COSMIC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	P01106	MYC	P49841	GSK3B	S161	A154G	154	Missense	distal	-7	no	9.025	9.001	EPSD	COSMIC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	P01106	MYC	P49841	GSK3B	S161	S159R	159	Missense	proximal	-2	no	9.025	8.909	EPSD	COSMIC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	P01106	MYC	P49841	GSK3B	S161	A165D	165	Missense	distal	4	no	9.025	9.013	EPSD	COSMIC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	P01106	MYC	P49841	GSK3B	S202	S203R	203	Missense	proximal	1	no	4.761	6.286	EPSD	COSMIC	6.007	Gain
CMGC_GSK_GSK3B_ST	P01106	MYC	P49841	GSK3B	S249	P245S	245	Missense	distal	-4	no	5.791	6.354	EPSD	COSMIC	6.007	Gain
CMGC_GSK_GSK3B_ST	P01106	MYC	P49841	GSK3B	S249	P246R	246	Missense	distal	-3	no	5.791	6.076	EPSD	COSMIC	6.007	Gain
CMGC_GSK_GSK3B_ST	P01106	MYC	P49841	GSK3B	S249	S250R	250	Missense	proximal	1	no	5.791	7.316	EPSD	COSMIC	6.007	Gain
CMGC_GSK_GSK3B_ST	P01106	MYC	P49841	GSK3B	S277	S283F	283	Missense	distal	6	no	7.755	7.742	EPSD	COSMIC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	P01106	MYC	P49841	GSK3B	S277	S277L	277	Missense	central	0	yes	7.755	0.000	EPSD	COSMIC	6.007	Loss
CMGC_GSK_GSK3B_ST	P01106	MYC	P49841	GSK3B	S277	S279C	279	Missense	proximal	2	no	7.755	7.262	EPSD	COSMIC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	P01106	MYC	P49841	GSK3B	S277	S283Y	283	Missense	distal	6	no	7.755	7.749	EPSD	COSMIC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	P01106	MYC	P49841	GSK3B	S277	P273H	273	Missense	distal	-4	no	7.755	7.230	EPSD	COSMIC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	P01106	MYC	P49841	GSK3B	S277	P282A	282	Missense	distal	5	no	7.755	6.726	EPSD	COSMIC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	P01106	MYC	P49841	GSK3B	S277	G280R	280	Missense	distal	3	no	7.755	7.340	EPSD	COSMIC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	P01106	MYC	P49841	GSK3B	S277	G274D	274	Missense	distal	-3	no	7.755	7.805	EPSD	COSMIC	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	P01106	MYC	P49841	GSK3B	S277	A272P	272	Missense	distal	-5	no	7.755	7.321	EPSD	COSMIC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	P01106	MYC	P49841	GSK3B	S277	S281F	281	Missense	distal	4	no	7.755	4.140	EPSD	COSMIC	6.007	Loss
CMGC_GSK_GSK3B_ST	P01106	MYC	P49841	GSK3B	S279	G280R	280	Missense	proximal	1	no	5.882	6.757	EPSD	COSMIC	6.007	Gain
CMGC_GSK_GSK3B_ST	P01106	MYC	P49841	GSK3B	S281	S283F	283	Missense	proximal	2	no	6.693	6.348	EPSD	COSMIC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	P01106	MYC	P49841	GSK3B	S281	S277L	277	Missense	distal	-4	no	6.693	5.343	EPSD	COSMIC	6.007	Loss
CMGC_GSK_GSK3B_ST	P01106	MYC	P49841	GSK3B	S281	H287Q	287	Missense	distal	6	no	6.693	6.699	EPSD	COSMIC	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	P01106	MYC	P49841	GSK3B	S281	S279C	279	Missense	proximal	-2	no	6.693	6.382	EPSD	COSMIC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	P01106	MYC	P49841	GSK3B	S281	S283Y	283	Missense	proximal	2	no	6.693	6.461	EPSD	COSMIC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	P01106	MYC	P49841	GSK3B	S281	P282A	282	Missense	proximal	1	no	6.693	2.961	EPSD	COSMIC	6.007	Loss
CMGC_GSK_GSK3B_ST	P01106	MYC	P49841	GSK3B	S281	G285E	285	Missense	distal	4	no	6.693	7.916	EPSD	COSMIC	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	P01106	MYC	P49841	GSK3B	S281	G280R	280	Missense	proximal	-1	no	6.693	6.549	EPSD	COSMIC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	P01106	MYC	P49841	GSK3B	S281	G274D	274	Missense	distal	-7	no	6.693	6.698	EPSD	COSMIC	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	P01106	MYC	P49841	GSK3B	S281	S281F	281	Missense	central	0	yes	6.693	0.000	EPSD	COSMIC	6.007	Loss
CMGC_GSK_GSK3B_ST	P01106	MYC	P49841	GSK3B	S344	S347F	347	Missense	distal	3	no	9.233	9.022	EPSD	COSMIC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	P01106	MYC	P49841	GSK3B	S344	E351K	351	Missense	distal	7	no	9.233	9.124	EPSD	COSMIC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	P01106	MYC	P49841	GSK3B	S344	S337T	337	Missense	distal	-7	no	9.233	9.260	EPSD	COSMIC	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	P35612	ADD2	P49841	GSK3B	S11	P13S	13	Missense	proximal	2	no	7.707	7.264	EPSD	COSMIC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	P35612	ADD2	P49841	GSK3B	S11	P7L	7	Missense	distal	-4	no	7.707	6.921	EPSD	COSMIC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	P35612	ADD2	P49841	GSK3B	S11	P15L	15	Missense	distal	4	no	7.707	7.961	EPSD	COSMIC	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	P35612	ADD2	P49841	GSK3B	S11	Q18R	18	Missense	distal	7	no	7.707	8.055	EPSD	COSMIC	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	P35612	ADD2	P49841	GSK3B	S11	P12S	12	Missense	proximal	1	no	7.707	3.863	EPSD	COSMIC	6.007	Loss
CMGC_GSK_GSK3B_ST	P35612	ADD2	P49841	GSK3B	S11	S11L	11	Missense	central	0	yes	7.707	0.000	EPSD	COSMIC	6.007	Loss
CMGC_GSK_GSK3B_ST	P35612	ADD2	P49841	GSK3B	S11	P7T	7	Missense	distal	-4	no	7.707	7.935	EPSD	COSMIC	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	P35612	ADD2	P49841	GSK3B	S11	Q16R	16	Missense	distal	5	no	7.707	8.046	EPSD	COSMIC	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	P35612	ADD2	P49841	GSK3B	S60	R53W	53	Missense	distal	-7	no	6.927	6.936	EPSD	COSMIC	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	P35612	ADD2	P49841	GSK3B	S60	R53Q	53	Missense	distal	-7	no	6.927	6.924	EPSD	COSMIC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	P35612	ADD2	P49841	GSK3B	S455	Q450H	450	Missense	distal	-5	no	6.726	6.750	EPSD	COSMIC	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	P35612	ADD2	P49841	GSK3B	S455	S455N	455	Missense	central	0	yes	6.726	0.000	EPSD	COSMIC	6.007	Loss
CMGC_GSK_GSK3B_ST	P35612	ADD2	P49841	GSK3B	S535	S528T	528	Missense	distal	-7	no	6.054	6.081	EPSD	COSMIC	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	P35612	ADD2	P49841	GSK3B	S592	G591A	591	Missense	proximal	-1	no	10.486	10.324	EPSD	COSMIC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	P35612	ADD2	P49841	GSK3B	S592	A594E	594	Missense	proximal	2	no	10.486	10.391	EPSD	COSMIC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	P35612	ADD2	P49841	GSK3B	S596	G591A	591	Missense	distal	-5	no	7.516	7.327	EPSD	COSMIC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	P35612	ADD2	P49841	GSK3B	S596	A594E	594	Missense	proximal	-2	no	7.516	7.748	EPSD	COSMIC	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	P35612	ADD2	P49841	GSK3B	S600	A594E	594	Missense	distal	-6	no	12.031	11.959	EPSD	COSMIC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	P35612	ADD2	P49841	GSK3B	S617	E624D	624	Missense	distal	7	no	9.420	9.436	EPSD	COSMIC	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	P35612	ADD2	P49841	GSK3B	S667	L662F	662	Missense	distal	-5	no	6.656	7.107	EPSD	COSMIC	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	P35612	ADD2	P49841	GSK3B	S667	S663N	663	Missense	distal	-4	no	6.656	5.359	EPSD	COSMIC	6.007	Loss
CMGC_GSK_GSK3B_ST	P35612	ADD2	P49841	GSK3B	S689	P694L	694	Missense	distal	5	no	8.096	6.815	EPSD	COSMIC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	P35612	ADD2	P49841	GSK3B	S689	S689G	689	Missense	central	0	yes	8.096	0.000	EPSD	COSMIC	6.007	Loss
CMGC_GSK_GSK3B_ST	P35612	ADD2	P49841	GSK3B	S689	D682N	682	Missense	distal	-7	no	8.096	8.099	EPSD	COSMIC	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	P35612	ADD2	P49841	GSK3B	S693	P694L	694	Missense	proximal	1	no	12.171	9.311	EPSD;PhosphoSitePlus	COSMIC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	P35612	ADD2	P49841	GSK3B	S693	S689G	689	Missense	distal	-4	no	12.171	11.743	EPSD;PhosphoSitePlus	COSMIC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	P35612	ADD2	P49841	GSK3B	S693	P698L	698	Missense	distal	5	no	12.171	10.890	EPSD;PhosphoSitePlus	COSMIC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	P35612	ADD2	P49841	GSK3B	S697	P694L	694	Missense	distal	-3	no	10.178	10.305	EPSD	COSMIC	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	P35612	ADD2	P49841	GSK3B	S697	P702S	702	Missense	distal	5	no	10.178	9.224	EPSD	COSMIC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	P35612	ADD2	P49841	GSK3B	S697	P698L	698	Missense	proximal	1	no	10.178	7.318	EPSD	COSMIC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	Q15691	MAPRE1	P49841	GSK3B	S7	N14Y	14	Missense	distal	7	no	5.735	6.054	EPSD	COSMIC	6.007	Gain
CMGC_GSK_GSK3B_ST	Q15691	MAPRE1	P49841	GSK3B	S165	P160H	160	Missense	distal	-5	no	6.685	7.008	EPSD	COSMIC	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	P25054	APC	P49841	GSK3B	T35	N30Y	30	Missense	distal	-5	no	5.620	6.564	EPSD	COSMIC	6.007	Gain
CMGC_GSK_GSK3B_ST	P25054	APC	P49841	GSK3B	S107	C110Y	110	Missense	distal	3	no	7.230	7.024	EPSD	COSMIC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	P25054	APC	P49841	GSK3B	S107	S105G	105	Missense	proximal	-2	no	7.230	7.113	EPSD	COSMIC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	P25054	APC	P49841	GSK3B	S111	M115I	115	Missense	distal	4	no	8.187	7.099	EPSD	COSMIC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	P25054	APC	P49841	GSK3B	S111	C110Y	110	Missense	proximal	-1	no	8.187	8.083	EPSD	COSMIC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	P25054	APC	P49841	GSK3B	S111	S117L	117	Missense	distal	6	no	8.187	8.182	EPSD	COSMIC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	P25054	APC	P49841	GSK3B	S111	S105G	105	Missense	distal	-6	no	8.187	8.203	EPSD	COSMIC	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	P25054	APC	P49841	GSK3B	S127	S130R	130	Missense	distal	3	no	6.184	5.813	EPSD	COSMIC	6.007	Loss
CMGC_GSK_GSK3B_ST	P25054	APC	P49841	GSK3B	S127	S130G	130	Missense	distal	3	no	6.184	6.228	EPSD	COSMIC;GDSC	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	P25054	APC	P49841	GSK3B	S127	G126R	126	Missense	proximal	-1	no	6.184	6.040	EPSD	COSMIC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	P25054	APC	P49841	GSK3B	S127	E129Q	129	Missense	proximal	2	no	6.184	6.494	EPSD	COSMIC	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	P25054	APC	P49841	GSK3B	S127	R128K	128	Missense	proximal	1	no	6.184	4.958	EPSD	COSMIC	6.007	Loss
CMGC_GSK_GSK3B_ST	P25054	APC	P49841	GSK3B	S127	N125K	125	Missense	proximal	-2	no	6.184	6.278	EPSD	COSMIC;CCLE	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	P25054	APC	P49841	GSK3B	S127	N125I	125	Missense	proximal	-2	no	6.184	6.402	EPSD	COSMIC	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	P25054	APC	P49841	GSK3B	S320	H325R	325	Missense	distal	5	no	5.386	6.375	EPSD	COSMIC;CCLE	6.007	Gain
CMGC_GSK_GSK3B_ST	P25054	APC	P49841	GSK3B	S744	L749F	749	Missense	distal	5	no	10.614	10.274	EPSD	COSMIC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	P25054	APC	P49841	GSK3B	S744	S744F	744	Missense	central	0	yes	10.614	0.000	EPSD	COSMIC	6.007	Loss
CMGC_GSK_GSK3B_ST	P25054	APC	P49841	GSK3B	S744	P745R	745	Missense	proximal	1	no	10.614	8.295	EPSD	COSMIC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	P25054	APC	P49841	GSK3B	S744	K738E	738	Missense	distal	-6	no	10.614	10.616	EPSD	COSMIC	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	P25054	APC	P49841	GSK3B	S747	L749F	749	Missense	proximal	2	no	6.209	5.805	EPSD	COSMIC	6.007	Loss
CMGC_GSK_GSK3B_ST	P25054	APC	P49841	GSK3B	S747	H753R	753	Missense	distal	6	no	6.209	6.215	EPSD	COSMIC	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	P25054	APC	P49841	GSK3B	S747	S744F	744	Missense	distal	-3	no	6.209	6.276	EPSD	COSMIC	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	P25054	APC	P49841	GSK3B	S747	P745R	745	Missense	proximal	-2	no	6.209	5.838	EPSD	COSMIC	6.007	Loss
CMGC_GSK_GSK3B_ST	P25054	APC	P49841	GSK3B	S780	L779V	779	Missense	proximal	-1	no	7.539	7.663	EPSD	COSMIC	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	P25054	APC	P49841	GSK3B	S780	N778D	778	Missense	proximal	-2	no	7.539	7.752	EPSD	COSMIC	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	P25054	APC	P49841	GSK3B	S780	K782E	782	Missense	proximal	2	no	7.539	7.499	EPSD	COSMIC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	P25054	APC	P49841	GSK3B	S780	D777Y	777	Missense	distal	-3	no	7.539	7.633	EPSD	COSMIC	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	P25054	APC	P49841	GSK3B	S780	P781L	781	Missense	proximal	1	no	7.539	4.679	EPSD	COSMIC	6.007	Loss
CMGC_GSK_GSK3B_ST	P25054	APC	P49841	GSK3B	S780	N775S	775	Missense	distal	-5	no	7.539	7.831	EPSD	COSMIC	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	P25054	APC	P49841	GSK3B	S780	L779S	779	Missense	proximal	-1	no	7.539	7.614	EPSD	COSMIC	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	P25054	APC	P49841	GSK3B	S780	H785D	785	Missense	distal	5	no	7.539	8.318	EPSD	COSMIC	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	P25054	APC	P49841	GSK3B	T899	A896S	896	Missense	distal	-3	no	6.638	6.617	EPSD	COSMIC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	P25054	APC	P49841	GSK3B	T899	H898Y	898	Missense	proximal	-1	no	6.638	6.549	EPSD	COSMIC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	P25054	APC	P49841	GSK3B	T899	S905G	905	Missense	distal	6	no	6.638	6.635	EPSD	COSMIC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	P25054	APC	P49841	GSK3B	T899	T899I	899	Missense	central	0	yes	6.638	0.000	EPSD	COSMIC	6.007	Loss
CMGC_GSK_GSK3B_ST	P25054	APC	P49841	GSK3B	T899	S906F	906	Missense	distal	7	no	6.638	6.715	EPSD	COSMIC	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	P25054	APC	P49841	GSK3B	T899	E893K	893	Missense	distal	-6	no	6.638	6.637	EPSD	COSMIC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	P25054	APC	P49841	GSK3B	T899	V894M	894	Missense	distal	-5	no	6.638	6.360	EPSD	COSMIC;CCLE	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	P25054	APC	P49841	GSK3B	T899	Q901R	901	Missense	proximal	2	no	6.638	6.433	EPSD	COSMIC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	P25054	APC	P49841	GSK3B	T899	D903G	903	Missense	distal	4	no	6.638	5.818	EPSD	COSMIC	6.007	Loss
CMGC_GSK_GSK3B_ST	P25054	APC	P49841	GSK3B	S906	T909I	909	Missense	distal	3	no	6.850	6.462	EPSD	COSMIC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	P25054	APC	P49841	GSK3B	S906	S905G	905	Missense	proximal	-1	no	6.850	6.856	EPSD	COSMIC	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	P25054	APC	P49841	GSK3B	S906	T909A	909	Missense	distal	3	no	6.850	6.545	EPSD	COSMIC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	P25054	APC	P49841	GSK3B	S906	H913D	913	Missense	distal	7	no	6.850	6.278	EPSD	COSMIC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	P25054	APC	P49841	GSK3B	S906	S908T	908	Missense	proximal	2	no	6.850	6.976	EPSD	COSMIC	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	P25054	APC	P49841	GSK3B	S906	S906F	906	Missense	central	0	yes	6.850	0.000	EPSD	COSMIC	6.007	Loss
CMGC_GSK_GSK3B_ST	P25054	APC	P49841	GSK3B	S906	L912V	912	Missense	distal	6	no	6.850	6.844	EPSD	COSMIC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	P25054	APC	P49841	GSK3B	S906	Q901R	901	Missense	distal	-5	no	6.850	7.404	EPSD	COSMIC	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	P25054	APC	P49841	GSK3B	S906	T909P	909	Missense	distal	3	no	6.850	6.900	EPSD	COSMIC	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	P25054	APC	P49841	GSK3B	S906	E911G	911	Missense	distal	5	no	6.850	6.584	EPSD	COSMIC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	P25054	APC	P49841	GSK3B	S906	D903G	903	Missense	distal	-3	no	6.850	6.799	EPSD	COSMIC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	P25054	APC	P49841	GSK3B	S966	S963I	963	Missense	distal	-3	no	8.445	8.559	EPSD	COSMIC	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	P25054	APC	P49841	GSK3B	S966	D971N	971	Missense	distal	5	no	8.445	8.019	EPSD	COSMIC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	P25054	APC	P49841	GSK3B	S966	Y973C	973	Missense	distal	7	no	8.445	8.395	EPSD	COSMIC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	P25054	APC	P49841	GSK3B	S966	S966R	966	Missense	central	0	yes	8.445	0.000	EPSD	COSMIC	6.007	Loss
CMGC_GSK_GSK3B_ST	P25054	APC	P49841	GSK3B	T1023	Y1027D	1027	Missense	distal	4	no	4.987	6.076	EPSD	COSMIC	6.007	Gain
CMGC_GSK_GSK3B_ST	P25054	APC	P49841	GSK3B	S1028	E1034D	1034	Missense	distal	6	no	7.279	7.278	EPSD	COSMIC;GDSC;CCLE	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	P25054	APC	P49841	GSK3B	S1028	Y1027D	1027	Missense	proximal	-1	no	7.279	7.359	EPSD	COSMIC	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	P25054	APC	P49841	GSK3B	S1028	N1026K	1026	Missense	proximal	-2	no	7.279	7.373	EPSD	COSMIC	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	P25054	APC	P49841	GSK3B	S1028	L1021V	1021	Missense	distal	-7	no	7.279	7.300	EPSD	COSMIC	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	P25054	APC	P49841	GSK3B	S1028	D1033N	1033	Missense	distal	5	no	7.279	6.852	EPSD	COSMIC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	P25054	APC	P49841	GSK3B	S1028	P1024A	1024	Missense	distal	-4	no	7.279	6.683	EPSD	COSMIC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	P25054	APC	P49841	GSK3B	S1028	I1025V	1025	Missense	distal	-3	no	7.279	7.333	EPSD	COSMIC	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	P25054	APC	P49841	GSK3B	S1028	I1025M	1025	Missense	distal	-3	no	7.279	7.137	EPSD	COSMIC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	P25054	APC	P49841	GSK3B	S1028	D1022H	1022	Missense	distal	-6	no	7.279	7.270	EPSD	COSMIC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	P25054	APC	P49841	GSK3B	S1028	K1030E	1030	Missense	proximal	2	no	7.279	7.239	EPSD	COSMIC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	P25054	APC	P49841	GSK3B	S1028	Y1027C	1027	Missense	proximal	-1	no	7.279	7.383	EPSD	COSMIC	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	P25054	APC	P49841	GSK3B	S1038	E1034D	1034	Missense	distal	-4	no	7.492	7.488	EPSD	COSMIC;GDSC;CCLE	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	P25054	APC	P49841	GSK3B	S1038	D1033N	1033	Missense	distal	-5	no	7.492	6.927	EPSD	COSMIC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	P25054	APC	P49841	GSK3B	S1038	Q1045H	1045	Missense	distal	7	no	7.492	8.028	EPSD	COSMIC	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	P25054	APC	P49841	GSK3B	S1100	P1101S	1101	Missense	proximal	1	no	9.022	5.177	EPSD	COSMIC	6.007	Loss
CMGC_GSK_GSK3B_ST	P25054	APC	P49841	GSK3B	S1100	E1097Q	1097	Missense	distal	-3	no	9.022	9.039	EPSD	COSMIC	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	P25054	APC	P49841	GSK3B	S1100	P1101L	1101	Missense	proximal	1	no	9.022	6.162	EPSD	COSMIC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	P25054	APC	P49841	GSK3B	S1100	G1106R	1106	Missense	distal	6	no	9.022	9.021	EPSD	COSMIC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	P25054	APC	P49841	GSK3B	S1100	Y1102H	1102	Missense	proximal	2	no	9.022	8.929	EPSD	COSMIC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	P25054	APC	P49841	GSK3B	S1100	V1099I	1099	Missense	proximal	-1	no	9.022	8.824	EPSD	COSMIC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	P25054	APC	P49841	GSK3B	S1104	N1108S	1108	Missense	distal	4	no	4.634	8.244	EPSD	COSMIC	6.007	Gain
CMGC_GSK_GSK3B_ST	P25054	APC	P49841	GSK3B	S1196	F1197L	1197	Missense	proximal	1	no	4.737	6.108	EPSD	COSMIC	6.007	Gain
CMGC_GSK_GSK3B_ST	P25054	APC	P49841	GSK3B	S1214	M1211R	1211	Missense	distal	-3	no	5.884	6.081	EPSD	COSMIC	6.007	Gain
CMGC_GSK_GSK3B_ST	P25054	APC	P49841	GSK3B	S1214	P1221A	1221	Missense	distal	7	no	5.884	6.295	EPSD	COSMIC	6.007	Gain
CMGC_GSK_GSK3B_ST	P25054	APC	P49841	GSK3B	S1214	E1209V	1209	Missense	distal	-5	no	5.884	6.033	EPSD	COSMIC	6.007	Gain
CMGC_GSK_GSK3B_ST	P25054	APC	P49841	GSK3B	T1218	M1211R	1211	Missense	distal	-7	no	6.412	6.409	EPSD	COSMIC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	P25054	APC	P49841	GSK3B	T1218	P1221L	1221	Missense	distal	3	no	6.412	6.093	EPSD	COSMIC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	P25054	APC	P49841	GSK3B	T1218	S1219T	1219	Missense	proximal	1	no	6.412	7.066	EPSD	COSMIC	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	P25054	APC	P49841	GSK3B	T1218	P1221A	1221	Missense	distal	3	no	6.412	6.057	EPSD	COSMIC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	P25054	APC	P49841	GSK3B	T1218	S1213L	1213	Missense	distal	-5	no	6.412	6.521	EPSD	COSMIC	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	P25054	APC	P49841	GSK3B	T1218	S1223Y	1223	Missense	distal	5	no	6.412	5.413	EPSD	COSMIC	6.007	Loss
CMGC_GSK_GSK3B_ST	P25054	APC	P49841	GSK3B	S1219	P1221L	1221	Missense	proximal	2	no	6.651	6.267	EPSD	COSMIC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	P25054	APC	P49841	GSK3B	S1219	P1221A	1221	Missense	proximal	2	no	6.651	6.214	EPSD	COSMIC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	P25054	APC	P49841	GSK3B	S1219	S1213L	1213	Missense	distal	-6	no	6.651	6.649	EPSD	COSMIC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	P25054	APC	P49841	GSK3B	S1219	S1223Y	1223	Missense	distal	4	no	6.651	3.138	EPSD	COSMIC	6.007	Loss
CMGC_GSK_GSK3B_ST	P25054	APC	P49841	GSK3B	T1267	C1263Y	1263	Missense	distal	-4	no	5.846	7.160	EPSD	COSMIC	6.007	Gain
CMGC_GSK_GSK3B_ST	P25054	APC	P49841	GSK3B	S1272	D1266G	1266	Missense	distal	-6	no	6.638	6.679	EPSD	COSMIC	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	P25054	APC	P49841	GSK3B	S1272	T1267S	1267	Missense	distal	-5	no	6.638	6.349	EPSD	COSMIC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	P25054	APC	P49841	GSK3B	S1272	S1275N	1275	Missense	distal	3	no	6.638	6.686	EPSD	COSMIC	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	P25054	APC	P49841	GSK3B	S1272	C1270W	1270	Missense	proximal	-2	no	6.638	7.040	EPSD	COSMIC	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	P25054	APC	P49841	GSK3B	S1272	C1274Y	1274	Missense	proximal	2	no	6.638	6.898	EPSD	COSMIC	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	P25054	APC	P49841	GSK3B	S1272	R1273K	1273	Missense	proximal	1	no	6.638	5.412	EPSD	COSMIC	6.007	Loss
CMGC_GSK_GSK3B_ST	P25054	APC	P49841	GSK3B	S1272	S1278P	1278	Missense	distal	6	no	6.638	6.640	EPSD	COSMIC	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	P25054	APC	P49841	GSK3B	S1272	L1277F	1277	Missense	distal	5	no	6.638	6.297	EPSD	COSMIC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	P25054	APC	P49841	GSK3B	S1272	S1276L	1276	Missense	distal	4	no	6.638	3.920	EPSD	COSMIC	6.007	Loss
CMGC_GSK_GSK3B_ST	P25054	APC	P49841	GSK3B	S1272	S1276T	1276	Missense	distal	4	no	6.638	5.769	EPSD	COSMIC	6.007	Loss
CMGC_GSK_GSK3B_ST	P25054	APC	P49841	GSK3B	S1272	S1275T	1275	Missense	distal	3	no	6.638	6.605	EPSD	COSMIC;CCLE	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	P25054	APC	P49841	GSK3B	S1272	D1266N	1266	Missense	distal	-6	no	6.638	6.660	EPSD	COSMIC	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	P25054	APC	P49841	GSK3B	S1272	C1270Y	1270	Missense	proximal	-2	no	6.638	6.630	EPSD	COSMIC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	P25054	APC	P49841	GSK3B	S1278	E1284D	1284	Missense	distal	6	no	6.066	6.065	EPSD	COSMIC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	P25054	APC	P49841	GSK3B	S1278	S1275N	1275	Missense	distal	-3	no	6.066	5.971	EPSD	COSMIC	6.007	Loss
CMGC_GSK_GSK3B_ST	P25054	APC	P49841	GSK3B	S1278	C1274Y	1274	Missense	distal	-4	no	6.066	7.380	EPSD	COSMIC	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	P25054	APC	P49841	GSK3B	S1278	D1285G	1285	Missense	distal	7	no	6.066	6.031	EPSD	COSMIC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	P25054	APC	P49841	GSK3B	S1278	R1273K	1273	Missense	distal	-5	no	6.066	5.569	EPSD	COSMIC	6.007	Loss
CMGC_GSK_GSK3B_ST	P25054	APC	P49841	GSK3B	S1278	S1278P	1278	Missense	central	0	yes	6.066	0.000	EPSD	COSMIC	6.007	Loss
CMGC_GSK_GSK3B_ST	P25054	APC	P49841	GSK3B	S1278	L1277F	1277	Missense	proximal	-1	no	6.066	6.011	EPSD	COSMIC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	P25054	APC	P49841	GSK3B	S1278	S1276L	1276	Missense	proximal	-2	no	6.066	5.992	EPSD	COSMIC	6.007	Loss
CMGC_GSK_GSK3B_ST	P25054	APC	P49841	GSK3B	S1278	S1276T	1276	Missense	proximal	-2	no	6.066	6.093	EPSD	COSMIC	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	P25054	APC	P49841	GSK3B	S1278	S1275T	1275	Missense	distal	-3	no	6.066	6.091	EPSD	COSMIC;CCLE	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	P25054	APC	P49841	GSK3B	S1340	S1341R	1341	Missense	proximal	1	no	5.468	6.993	EPSD	COSMIC	6.007	Gain
CMGC_GSK_GSK3B_ST	P25054	APC	P49841	GSK3B	S1340	R1336S	1336	Missense	distal	-4	no	5.468	6.655	EPSD	COSMIC	6.007	Gain
CMGC_GSK_GSK3B_ST	P25054	APC	P49841	GSK3B	S1341	S1346P	1346	Missense	distal	5	no	5.530	6.484	EPSD	COSMIC	6.007	Gain
CMGC_GSK_GSK3B_ST	P25054	APC	P49841	GSK3B	S1355	S1356P	1356	Missense	proximal	1	no	2.442	6.287	EPSD	COSMIC	6.007	Gain
CMGC_GSK_GSK3B_ST	P25054	APC	P49841	GSK3B	S1356	K1363I	1363	Missense	distal	7	no	5.811	6.216	EPSD	COSMIC	6.007	Gain
CMGC_GSK_GSK3B_ST	P25054	APC	P49841	GSK3B	S1356	F1354L	1354	Missense	proximal	-2	no	5.811	6.067	EPSD	COSMIC	6.007	Gain
CMGC_GSK_GSK3B_ST	P25054	APC	P49841	GSK3B	S1356	G1357R	1357	Missense	proximal	1	no	5.811	6.685	EPSD	COSMIC	6.007	Gain
CMGC_GSK_GSK3B_ST	P25054	APC	P49841	GSK3B	S1356	G1357V	1357	Missense	proximal	1	no	5.811	6.014	EPSD	COSMIC	6.007	Gain
CMGC_GSK_GSK3B_ST	P25054	APC	P49841	GSK3B	S1360	A1366G	1366	Missense	distal	6	no	10.460	10.459	EPSD	COSMIC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	P25054	APC	P49841	GSK3B	S1360	S1355F	1355	Missense	distal	-5	no	10.460	11.020	EPSD	COSMIC	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	P25054	APC	P49841	GSK3B	S1360	A1358E	1358	Missense	proximal	-2	no	10.460	10.692	EPSD	COSMIC	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	P25054	APC	P49841	GSK3B	S1360	S1355P	1355	Missense	distal	-5	no	10.460	10.303	EPSD	COSMIC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	P25054	APC	P49841	GSK3B	S1360	P1361L	1361	Missense	proximal	1	no	10.460	7.599	EPSD	COSMIC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	P25054	APC	P49841	GSK3B	S1360	S1362F	1362	Missense	proximal	2	no	10.460	10.115	EPSD	COSMIC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	P25054	APC	P49841	GSK3B	S1360	S1364R	1364	Missense	distal	4	no	10.460	7.422	EPSD	COSMIC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	P25054	APC	P49841	GSK3B	S1360	A1358S	1358	Missense	proximal	-2	no	10.460	10.795	EPSD	COSMIC	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	P25054	APC	P49841	GSK3B	S1360	K1363I	1363	Missense	distal	3	no	10.460	10.166	EPSD	COSMIC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	P25054	APC	P49841	GSK3B	S1360	K1363E	1363	Missense	distal	3	no	10.460	10.567	EPSD	COSMIC	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	P25054	APC	P49841	GSK3B	S1360	Q1367R	1367	Missense	distal	7	no	10.460	10.808	EPSD	COSMIC	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	P25054	APC	P49841	GSK3B	S1360	S1356P	1356	Missense	distal	-4	no	10.460	9.897	EPSD	COSMIC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	P25054	APC	P49841	GSK3B	S1360	A1358T	1358	Missense	proximal	-2	no	10.460	10.822	EPSD	COSMIC;GDSC;CCLE	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	P25054	APC	P49841	GSK3B	S1360	F1354L	1354	Missense	distal	-6	no	10.460	10.512	EPSD	COSMIC	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	P25054	APC	P49841	GSK3B	S1360	E1353D	1353	Missense	distal	-7	no	10.460	10.430	EPSD	COSMIC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	P25054	APC	P49841	GSK3B	S1360	G1357R	1357	Missense	distal	-3	no	10.460	10.633	EPSD	COSMIC	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	P25054	APC	P49841	GSK3B	S1360	S1355Y	1355	Missense	distal	-5	no	10.460	11.112	EPSD	COSMIC	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	P25054	APC	P49841	GSK3B	S1360	G1357E	1357	Missense	distal	-3	no	10.460	10.477	EPSD	COSMIC	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	P25054	APC	P49841	GSK3B	S1360	S1360F	1360	Missense	central	0	yes	10.460	0.000	EPSD	COSMIC	6.007	Loss
CMGC_GSK_GSK3B_ST	P25054	APC	P49841	GSK3B	S1360	E1353K	1353	Missense	distal	-7	no	10.460	10.449	EPSD	COSMIC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	P25054	APC	P49841	GSK3B	S1360	Q1367H	1367	Missense	distal	7	no	10.460	10.996	EPSD	COSMIC	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	P25054	APC	P49841	GSK3B	S1360	E1353V	1353	Missense	distal	-7	no	10.460	10.449	EPSD	COSMIC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	P25054	APC	P49841	GSK3B	S1360	G1365D	1365	Missense	distal	5	no	10.460	10.524	EPSD	COSMIC	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	P25054	APC	P49841	GSK3B	S1360	G1357V	1357	Missense	distal	-3	no	10.460	10.631	EPSD	COSMIC	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	P25054	APC	P49841	GSK3B	S1364	A1366G	1366	Missense	proximal	2	no	7.800	7.534	EPSD	COSMIC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	P25054	APC	P49841	GSK3B	S1364	A1358E	1358	Missense	distal	-6	no	7.800	7.728	EPSD	COSMIC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	P25054	APC	P49841	GSK3B	S1364	P1361L	1361	Missense	distal	-3	no	7.800	7.926	EPSD	COSMIC	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	P25054	APC	P49841	GSK3B	S1364	S1362F	1362	Missense	proximal	-2	no	7.800	7.470	EPSD	COSMIC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	P25054	APC	P49841	GSK3B	S1364	T1368I	1368	Missense	distal	4	no	7.800	5.347	EPSD	COSMIC	6.007	Loss
CMGC_GSK_GSK3B_ST	P25054	APC	P49841	GSK3B	S1364	S1364R	1364	Missense	central	0	yes	7.800	0.000	EPSD	COSMIC	6.007	Loss
CMGC_GSK_GSK3B_ST	P25054	APC	P49841	GSK3B	S1364	P1369H	1369	Missense	distal	5	no	7.800	6.173	EPSD	COSMIC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	P25054	APC	P49841	GSK3B	S1364	A1358S	1358	Missense	distal	-6	no	7.800	7.790	EPSD	COSMIC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	P25054	APC	P49841	GSK3B	S1364	K1363I	1363	Missense	proximal	-1	no	7.800	7.595	EPSD	COSMIC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	P25054	APC	P49841	GSK3B	S1364	K1363E	1363	Missense	proximal	-1	no	7.800	7.733	EPSD	COSMIC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	P25054	APC	P49841	GSK3B	S1364	Q1367R	1367	Missense	distal	3	no	7.800	7.467	EPSD	COSMIC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	P25054	APC	P49841	GSK3B	S1364	A1358T	1358	Missense	distal	-6	no	7.800	7.732	EPSD	COSMIC;GDSC;CCLE	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	P25054	APC	P49841	GSK3B	S1364	G1357R	1357	Missense	distal	-7	no	7.800	7.821	EPSD	COSMIC	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	P25054	APC	P49841	GSK3B	S1364	G1357E	1357	Missense	distal	-7	no	7.800	7.835	EPSD	COSMIC	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	P25054	APC	P49841	GSK3B	S1364	S1360F	1360	Missense	distal	-4	no	7.800	6.646	EPSD	COSMIC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	P25054	APC	P49841	GSK3B	S1364	Q1367H	1367	Missense	distal	3	no	7.800	7.809	EPSD	COSMIC	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	P25054	APC	P49841	GSK3B	S1364	T1368S	1368	Missense	distal	4	no	7.800	8.669	EPSD	COSMIC	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	P25054	APC	P49841	GSK3B	S1364	G1365D	1365	Missense	proximal	1	no	7.800	7.891	EPSD	COSMIC	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	P25054	APC	P49841	GSK3B	S1364	T1368K	1368	Missense	distal	4	no	7.800	5.467	EPSD	COSMIC	6.007	Loss
CMGC_GSK_GSK3B_ST	P25054	APC	P49841	GSK3B	S1364	G1357V	1357	Missense	distal	-7	no	7.800	7.824	EPSD	COSMIC	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	P25054	APC	P49841	GSK3B	T1368	A1366G	1366	Missense	proximal	-2	no	7.906	8.123	EPSD	COSMIC	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	P25054	APC	P49841	GSK3B	T1368	P1361L	1361	Missense	distal	-7	no	7.906	7.907	EPSD	COSMIC	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	P25054	APC	P49841	GSK3B	T1368	S1362F	1362	Missense	distal	-6	no	7.906	7.852	EPSD	COSMIC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	P25054	APC	P49841	GSK3B	T1368	P1373S	1373	Missense	distal	5	no	7.906	6.952	EPSD	COSMIC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	P25054	APC	P49841	GSK3B	T1368	T1368I	1368	Missense	central	0	yes	7.906	0.000	EPSD	COSMIC	6.007	Loss
CMGC_GSK_GSK3B_ST	P25054	APC	P49841	GSK3B	T1368	S1364R	1364	Missense	distal	-4	no	7.906	6.719	EPSD	COSMIC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	P25054	APC	P49841	GSK3B	T1368	P1369H	1369	Missense	proximal	1	no	7.906	4.205	EPSD	COSMIC	6.007	Loss
CMGC_GSK_GSK3B_ST	P25054	APC	P49841	GSK3B	T1368	K1363I	1363	Missense	distal	-5	no	7.906	8.178	EPSD	COSMIC	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	P25054	APC	P49841	GSK3B	T1368	K1363E	1363	Missense	distal	-5	no	7.906	8.136	EPSD	COSMIC	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	P25054	APC	P49841	GSK3B	T1368	Q1367R	1367	Missense	proximal	-1	no	7.906	7.875	EPSD	COSMIC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	P25054	APC	P49841	GSK3B	T1368	H1375Y	1375	Missense	distal	7	no	7.906	7.722	EPSD	COSMIC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	P25054	APC	P49841	GSK3B	T1368	Q1367H	1367	Missense	proximal	-1	no	7.906	7.961	EPSD	COSMIC	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	P25054	APC	P49841	GSK3B	T1368	P1373T	1373	Missense	distal	5	no	7.906	6.929	EPSD	COSMIC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	P25054	APC	P49841	GSK3B	T1368	P1373L	1373	Missense	distal	5	no	7.906	6.625	EPSD	COSMIC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	P25054	APC	P49841	GSK3B	T1368	G1365D	1365	Missense	distal	-3	no	7.906	7.956	EPSD	COSMIC	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	P25054	APC	P49841	GSK3B	T1368	T1368K	1368	Missense	central	0	yes	7.906	0.000	EPSD	COSMIC	6.007	Loss
CMGC_GSK_GSK3B_ST	P25054	APC	P49841	GSK3B	S1371	A1366G	1366	Missense	distal	-5	no	6.484	6.673	EPSD	COSMIC	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	P25054	APC	P49841	GSK3B	S1371	P1373S	1373	Missense	proximal	2	no	6.484	6.040	EPSD	COSMIC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	P25054	APC	P49841	GSK3B	S1371	T1368I	1368	Missense	distal	-3	no	6.484	6.573	EPSD	COSMIC	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	P25054	APC	P49841	GSK3B	S1371	S1364R	1364	Missense	distal	-7	no	6.484	6.502	EPSD	COSMIC	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	P25054	APC	P49841	GSK3B	S1371	P1369H	1369	Missense	proximal	-2	no	6.484	6.123	EPSD	COSMIC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	P25054	APC	P49841	GSK3B	S1371	E1374K	1374	Missense	distal	3	no	6.484	6.377	EPSD	COSMIC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	P25054	APC	P49841	GSK3B	S1371	Q1367R	1367	Missense	distal	-4	no	6.484	6.127	EPSD	COSMIC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	P25054	APC	P49841	GSK3B	S1371	H1375Y	1375	Missense	distal	4	no	6.484	6.727	EPSD	COSMIC	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	P25054	APC	P49841	GSK3B	S1371	Q1367H	1367	Missense	distal	-4	no	6.484	6.226	EPSD	COSMIC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	P25054	APC	P49841	GSK3B	S1371	P1373T	1373	Missense	proximal	2	no	6.484	6.167	EPSD	COSMIC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	P25054	APC	P49841	GSK3B	S1371	P1373L	1373	Missense	proximal	2	no	6.484	6.100	EPSD	COSMIC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	P25054	APC	P49841	GSK3B	S1371	T1368S	1368	Missense	distal	-3	no	6.484	6.459	EPSD	COSMIC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	P25054	APC	P49841	GSK3B	S1371	G1365D	1365	Missense	distal	-6	no	6.484	6.443	EPSD	COSMIC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	P25054	APC	P49841	GSK3B	S1371	T1368K	1368	Missense	distal	-3	no	6.484	6.483	EPSD	COSMIC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	P25054	APC	P49841	GSK3B	T1380	R1386S	1386	Missense	distal	6	no	6.505	6.509	EPSD	COSMIC	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	P25054	APC	P49841	GSK3B	T1380	S1385R	1385	Missense	distal	5	no	6.505	6.821	EPSD	COSMIC	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	P25054	APC	P49841	GSK3B	T1380	P1373S	1373	Missense	distal	-7	no	6.505	6.506	EPSD	COSMIC	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	P25054	APC	P49841	GSK3B	T1380	C1387S	1387	Missense	distal	7	no	6.505	6.113	EPSD	COSMIC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	P25054	APC	P49841	GSK3B	T1380	P1381L	1381	Missense	proximal	1	no	6.505	3.644	EPSD	COSMIC	6.007	Loss
CMGC_GSK_GSK3B_ST	P25054	APC	P49841	GSK3B	T1380	T1380I	1380	Missense	central	0	yes	6.505	0.000	EPSD	COSMIC	6.007	Loss
CMGC_GSK_GSK3B_ST	P25054	APC	P49841	GSK3B	T1380	E1374K	1374	Missense	distal	-6	no	6.505	6.504	EPSD	COSMIC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	P25054	APC	P49841	GSK3B	T1380	L1382F	1382	Missense	proximal	2	no	6.505	6.100	EPSD	COSMIC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	P25054	APC	P49841	GSK3B	T1380	E1379G	1379	Missense	proximal	-1	no	6.505	6.523	EPSD	COSMIC	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	P25054	APC	P49841	GSK3B	T1380	H1375Y	1375	Missense	distal	-5	no	6.505	6.990	EPSD	COSMIC	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	P25054	APC	P49841	GSK3B	T1380	L1382P	1382	Missense	proximal	2	no	6.505	6.889	EPSD	COSMIC	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	P25054	APC	P49841	GSK3B	T1380	P1373T	1373	Missense	distal	-7	no	6.505	6.533	EPSD	COSMIC	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	P25054	APC	P49841	GSK3B	T1380	P1373L	1373	Missense	distal	-7	no	6.505	6.506	EPSD	COSMIC	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	P25054	APC	P49841	GSK3B	S1385	V1390I	1390	Missense	distal	5	no	6.310	6.145	EPSD	COSMIC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	P25054	APC	P49841	GSK3B	S1385	R1386S	1386	Missense	proximal	1	no	6.310	4.785	EPSD	COSMIC	6.007	Loss
CMGC_GSK_GSK3B_ST	P25054	APC	P49841	GSK3B	S1385	S1389C	1389	Missense	distal	4	no	6.310	0.178	EPSD	COSMIC	6.007	Loss
CMGC_GSK_GSK3B_ST	P25054	APC	P49841	GSK3B	S1385	S1385R	1385	Missense	central	0	yes	6.310	0.000	EPSD	COSMIC	6.007	Loss
CMGC_GSK_GSK3B_ST	P25054	APC	P49841	GSK3B	S1385	C1387S	1387	Missense	proximal	2	no	6.310	6.803	EPSD	COSMIC	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	P25054	APC	P49841	GSK3B	S1385	P1381L	1381	Missense	distal	-4	no	6.310	5.524	EPSD	COSMIC	6.007	Loss
CMGC_GSK_GSK3B_ST	P25054	APC	P49841	GSK3B	S1385	T1380I	1380	Missense	distal	-5	no	6.310	6.494	EPSD	COSMIC	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	P25054	APC	P49841	GSK3B	S1385	L1382F	1382	Missense	distal	-3	no	6.310	6.368	EPSD	COSMIC	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	P25054	APC	P49841	GSK3B	S1385	E1379G	1379	Missense	distal	-6	no	6.310	6.388	EPSD	COSMIC	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	P25054	APC	P49841	GSK3B	S1385	L1382P	1382	Missense	distal	-3	no	6.310	6.184	EPSD	COSMIC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	P25054	APC	P49841	GSK3B	S1385	V1390D	1390	Missense	distal	5	no	6.310	6.918	EPSD	COSMIC	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	P25054	APC	P49841	GSK3B	S1385	S1389Y	1389	Missense	distal	4	no	6.310	2.797	EPSD	COSMIC	6.007	Loss
CMGC_GSK_GSK3B_ST	P25054	APC	P49841	GSK3B	S1391	C1387S	1387	Missense	distal	-4	no	5.161	7.276	EPSD	COSMIC	6.007	Gain
CMGC_GSK_GSK3B_ST	P25054	APC	P49841	GSK3B	S1392	L1393P	1393	Missense	proximal	1	no	3.789	6.649	EPSD	COSMIC	6.007	Gain
CMGC_GSK_GSK3B_ST	P25054	APC	P49841	GSK3B	S1398	S1395C	1395	Missense	distal	-3	no	5.949	6.052	EPSD	COSMIC	6.007	Gain
CMGC_GSK_GSK3B_ST	P25054	APC	P49841	GSK3B	S1426	P1432H	1432	Missense	distal	6	no	7.675	7.663	EPSD	COSMIC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	P25054	APC	P49841	GSK3B	S1426	L1423F	1423	Missense	distal	-3	no	7.675	7.733	EPSD	COSMIC	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	P25054	APC	P49841	GSK3B	S1426	P1433L	1433	Missense	distal	7	no	7.675	7.724	EPSD	COSMIC	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	P25054	APC	P49841	GSK3B	S1426	D1422G	1422	Missense	distal	-4	no	7.675	7.848	EPSD	COSMIC	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	P25054	APC	P49841	GSK3B	S1426	M1431V	1431	Missense	distal	5	no	7.675	7.313	EPSD	COSMIC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	P25054	APC	P49841	GSK3B	S1426	G1428E	1428	Missense	proximal	2	no	7.675	7.846	EPSD	COSMIC	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	P25054	APC	P49841	GSK3B	S1426	M1431R	1431	Missense	distal	5	no	7.675	8.131	EPSD	COSMIC	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	P25054	APC	P49841	GSK3B	S1426	D1422H	1422	Missense	distal	-4	no	7.675	7.188	EPSD	COSMIC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	P25054	APC	P49841	GSK3B	S1426	P1420L	1420	Missense	distal	-6	no	7.675	7.653	EPSD	COSMIC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	P25054	APC	P49841	GSK3B	S1426	P1427S	1427	Missense	proximal	1	no	7.675	3.830	EPSD	COSMIC	6.007	Loss
CMGC_GSK_GSK3B_ST	P25054	APC	P49841	GSK3B	S1426	Q1429H	1429	Missense	distal	3	no	7.675	7.684	EPSD	COSMIC	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	P25054	APC	P49841	GSK3B	S1426	T1430S	1430	Missense	distal	4	no	7.675	8.544	EPSD	COSMIC	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	P25054	APC	P49841	GSK3B	S1426	D1425A	1425	Missense	proximal	-1	no	7.675	7.581	EPSD	COSMIC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	P25054	APC	P49841	GSK3B	S1426	S1426N	1426	Missense	central	0	yes	7.675	0.000	EPSD	COSMIC	6.007	Loss
CMGC_GSK_GSK3B_ST	P25054	APC	P49841	GSK3B	S1426	P1432S	1432	Missense	distal	6	no	7.675	7.673	EPSD	COSMIC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	P25054	APC	P49841	GSK3B	S1436	P1440S	1440	Missense	distal	4	no	3.911	6.882	EPSD	COSMIC	6.007	Gain
CMGC_GSK_GSK3B_ST	P25054	APC	P49841	GSK3B	T1438	P1432H	1432	Missense	distal	-6	no	8.114	8.059	EPSD	COSMIC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	P25054	APC	P49841	GSK3B	T1438	P1440S	1440	Missense	proximal	2	no	8.114	7.670	EPSD	COSMIC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	P25054	APC	P49841	GSK3B	T1438	R1435G	1435	Missense	distal	-3	no	8.114	7.941	EPSD	COSMIC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	P25054	APC	P49841	GSK3B	T1438	P1433L	1433	Missense	distal	-5	no	8.114	8.380	EPSD	COSMIC	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	P25054	APC	P49841	GSK3B	T1438	P1441A	1441	Missense	distal	3	no	8.114	7.759	EPSD	COSMIC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	P25054	APC	P49841	GSK3B	T1438	P1443L	1443	Missense	distal	5	no	8.114	6.834	EPSD	COSMIC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	P25054	APC	P49841	GSK3B	T1438	S1434N	1434	Missense	distal	-4	no	8.114	6.817	EPSD	COSMIC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	P25054	APC	P49841	GSK3B	T1438	P1439S	1439	Missense	proximal	1	no	8.114	4.269	EPSD	COSMIC	6.007	Loss
CMGC_GSK_GSK3B_ST	P25054	APC	P49841	GSK3B	T1438	P1439L	1439	Missense	proximal	1	no	8.114	5.254	EPSD	COSMIC	6.007	Loss
CMGC_GSK_GSK3B_ST	P25054	APC	P49841	GSK3B	T1438	T1438A	1438	Missense	central	0	yes	8.114	0.000	EPSD	COSMIC	6.007	Loss
CMGC_GSK_GSK3B_ST	P25054	APC	P49841	GSK3B	T1438	M1431R	1431	Missense	distal	-7	no	8.114	8.111	EPSD	COSMIC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	P25054	APC	P49841	GSK3B	T1438	P1442S	1442	Missense	distal	4	no	8.114	11.085	EPSD	COSMIC	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	P25054	APC	P49841	GSK3B	T1438	T1445I	1445	Missense	distal	7	no	8.114	8.509	EPSD	COSMIC	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	P25054	APC	P49841	GSK3B	T1438	S1434C	1434	Missense	distal	-4	no	8.114	6.000	EPSD	COSMIC	6.007	Loss
CMGC_GSK_GSK3B_ST	P25054	APC	P49841	GSK3B	T1438	P1441L	1441	Missense	distal	3	no	8.114	7.796	EPSD	COSMIC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	P25054	APC	P49841	GSK3B	T1438	T1438I	1438	Missense	central	0	yes	8.114	0.000	EPSD	COSMIC	6.007	Loss
CMGC_GSK_GSK3B_ST	P25054	APC	P49841	GSK3B	T1438	S1434R	1434	Missense	distal	-4	no	8.114	6.927	EPSD	COSMIC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	P25054	APC	P49841	GSK3B	T1438	P1440L	1440	Missense	proximal	2	no	8.114	7.730	EPSD	COSMIC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	P25054	APC	P49841	GSK3B	T1438	P1441S	1441	Missense	distal	3	no	8.114	8.096	EPSD	COSMIC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	P25054	APC	P49841	GSK3B	T1438	P1432S	1432	Missense	distal	-6	no	8.114	8.093	EPSD	COSMIC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	P25054	APC	P49841	GSK3B	T1438	P1443T	1443	Missense	distal	5	no	8.114	7.137	EPSD	COSMIC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	P25054	APC	P49841	GSK3B	S1501	S1501A	1501	Missense	central	0	yes	8.486	0.000	EPSD;PhosphoSitePlus	COSMIC	6.007	Loss
CMGC_GSK_GSK3B_ST	P25054	APC	P49841	GSK3B	S1501	P1497S	1497	Missense	distal	-4	no	8.486	9.050	EPSD;PhosphoSitePlus	COSMIC	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	P25054	APC	P49841	GSK3B	S1501	G1499R	1499	Missense	proximal	-2	no	8.486	8.489	EPSD;PhosphoSitePlus	COSMIC	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	P25054	APC	P49841	GSK3B	S1501	E1494K	1494	Missense	distal	-7	no	8.486	8.475	EPSD;PhosphoSitePlus	COSMIC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	P25054	APC	P49841	GSK3B	S1501	S1495G	1495	Missense	distal	-6	no	8.486	8.503	EPSD;PhosphoSitePlus	COSMIC	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	P25054	APC	P49841	GSK3B	S1501	D1498N	1498	Missense	distal	-3	no	8.486	8.346	EPSD;PhosphoSitePlus	COSMIC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	P25054	APC	P49841	GSK3B	S1501	S1495I	1495	Missense	distal	-6	no	8.486	8.424	EPSD;PhosphoSitePlus	COSMIC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	P25054	APC	P49841	GSK3B	S1501	S1504F	1504	Missense	distal	3	no	8.486	8.276	EPSD;PhosphoSitePlus	COSMIC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	P25054	APC	P49841	GSK3B	S1501	A1508V	1508	Missense	distal	7	no	8.486	8.564	EPSD;PhosphoSitePlus	COSMIC	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	P25054	APC	P49841	GSK3B	S1501	P1497L	1497	Missense	distal	-4	no	8.486	7.700	EPSD;PhosphoSitePlus	COSMIC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	P25054	APC	P49841	GSK3B	S1501	S1503L	1503	Missense	proximal	2	no	8.486	8.546	EPSD;PhosphoSitePlus	COSMIC	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	P25054	APC	P49841	GSK3B	S1501	S1501F	1501	Missense	central	0	yes	8.486	0.000	EPSD;PhosphoSitePlus	COSMIC	6.007	Loss
CMGC_GSK_GSK3B_ST	P25054	APC	P49841	GSK3B	S1503	S1501A	1501	Missense	proximal	-2	no	6.247	5.912	PhosphoSitePlus;EPSD	COSMIC	6.007	Loss
CMGC_GSK_GSK3B_ST	P25054	APC	P49841	GSK3B	S1503	P1497S	1497	Missense	distal	-6	no	6.247	6.226	PhosphoSitePlus;EPSD	COSMIC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	P25054	APC	P49841	GSK3B	S1503	G1499R	1499	Missense	distal	-4	no	6.247	5.488	PhosphoSitePlus;EPSD	COSMIC	6.007	Loss
CMGC_GSK_GSK3B_ST	P25054	APC	P49841	GSK3B	S1503	D1498N	1498	Missense	distal	-5	no	6.247	5.682	PhosphoSitePlus;EPSD	COSMIC	6.007	Loss
CMGC_GSK_GSK3B_ST	P25054	APC	P49841	GSK3B	S1503	S1504F	1504	Missense	proximal	1	no	6.247	5.860	PhosphoSitePlus;EPSD	COSMIC	6.007	Loss
CMGC_GSK_GSK3B_ST	P25054	APC	P49841	GSK3B	S1503	A1508V	1508	Missense	distal	5	no	6.247	5.820	PhosphoSitePlus;EPSD	COSMIC	6.007	Loss
CMGC_GSK_GSK3B_ST	P25054	APC	P49841	GSK3B	S1503	P1497L	1497	Missense	distal	-6	no	6.247	6.224	PhosphoSitePlus;EPSD	COSMIC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	P25054	APC	P49841	GSK3B	S1503	S1503L	1503	Missense	central	0	yes	6.247	0.000	PhosphoSitePlus;EPSD	COSMIC	6.007	Loss
CMGC_GSK_GSK3B_ST	P25054	APC	P49841	GSK3B	S1503	S1501F	1501	Missense	proximal	-2	no	6.247	5.916	PhosphoSitePlus;EPSD	COSMIC	6.007	Loss
CMGC_GSK_GSK3B_ST	P25054	APC	P49841	GSK3B	S1510	P1514S	1514	Missense	distal	4	no	3.054	6.025	EPSD	COSMIC	6.007	Gain
CMGC_GSK_GSK3B_ST	P25054	APC	P49841	GSK3B	S1581	A1582P	1582	Missense	proximal	1	no	4.942	8.675	EPSD	COSMIC	6.007	Gain
CMGC_GSK_GSK3B_ST	P25054	APC	P49841	GSK3B	T1633	T1633I	1633	Missense	central	0	yes	6.346	0.000	EPSD	COSMIC	6.007	Loss
CMGC_GSK_GSK3B_ST	P25054	APC	P49841	GSK3B	T1633	R1640Q	1640	Missense	distal	7	no	6.346	5.998	EPSD	COSMIC	6.007	Loss
CMGC_GSK_GSK3B_ST	P25054	APC	P49841	GSK3B	T1633	Q1627P	1627	Missense	distal	-6	no	6.346	6.372	EPSD	COSMIC	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	P25054	APC	P49841	GSK3B	T1633	D1637N	1637	Missense	distal	4	no	6.346	5.160	EPSD	COSMIC	6.007	Loss
CMGC_GSK_GSK3B_ST	P25054	APC	P49841	GSK3B	T1633	P1639S	1639	Missense	distal	6	no	6.346	6.344	EPSD	COSMIC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	P25054	APC	P49841	GSK3B	T1633	D1637Y	1637	Missense	distal	4	no	6.346	5.257	EPSD	COSMIC	6.007	Loss
CMGC_GSK_GSK3B_ST	P25054	APC	P49841	GSK3B	T1633	P1626S	1626	Missense	distal	-7	no	6.346	6.348	EPSD	COSMIC	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	P25054	APC	P49841	GSK3B	T1633	R1640L	1640	Missense	distal	7	no	6.346	5.894	EPSD	COSMIC	6.007	Loss
CMGC_GSK_GSK3B_ST	P25054	APC	P49841	GSK3B	T1647	S1652P	1652	Missense	distal	5	no	5.811	6.765	EPSD	COSMIC	6.007	Gain
CMGC_GSK_GSK3B_ST	P25054	APC	P49841	GSK3B	T1647	C1643Y	1643	Missense	distal	-4	no	5.811	7.125	EPSD	COSMIC	6.007	Gain
CMGC_GSK_GSK3B_ST	P25054	APC	P49841	GSK3B	S1652	S1652P	1652	Missense	central	0	yes	6.674	0.000	EPSD	COSMIC	6.007	Loss
CMGC_GSK_GSK3B_ST	P25054	APC	P49841	GSK3B	S1652	S1656F	1656	Missense	distal	4	no	6.674	3.059	EPSD	COSMIC	6.007	Loss
CMGC_GSK_GSK3B_ST	P25054	APC	P49841	GSK3B	S1652	P1648A	1648	Missense	distal	-4	no	6.674	6.077	EPSD	COSMIC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	P25054	APC	P49841	GSK3B	S1652	S1656Y	1656	Missense	distal	4	no	6.674	3.161	EPSD	COSMIC;GDSC;CCLE	6.007	Loss
CMGC_GSK_GSK3B_ST	P25054	APC	P49841	GSK3B	S1652	E1645Q	1645	Missense	distal	-7	no	6.674	6.656	EPSD	COSMIC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	P25054	APC	P49841	GSK3B	S1652	L1657R	1657	Missense	distal	5	no	6.674	7.317	EPSD	COSMIC	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	P25054	APC	P49841	GSK3B	S1652	S1658R	1658	Missense	distal	6	no	6.674	6.669	EPSD	COSMIC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	P25054	APC	P49841	GSK3B	S1664	A1670V	1670	Missense	distal	6	no	8.205	8.197	EPSD	COSMIC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	P25054	APC	P49841	GSK3B	S1664	P1666L	1666	Missense	proximal	2	no	8.205	7.821	EPSD	COSMIC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	P25054	APC	P49841	GSK3B	S1664	L1660P	1660	Missense	distal	-4	no	8.205	8.992	EPSD	COSMIC	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	P25054	APC	P49841	GSK3B	S1664	E1663K	1663	Missense	proximal	-1	no	8.205	8.272	EPSD	COSMIC	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	P25054	APC	P49841	GSK3B	S1664	L1669S	1669	Missense	distal	5	no	8.205	8.531	EPSD	COSMIC	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	P25054	APC	P49841	GSK3B	S1664	S1664F	1664	Missense	central	0	yes	8.205	0.000	EPSD	COSMIC	6.007	Loss
CMGC_GSK_GSK3B_ST	P25054	APC	P49841	GSK3B	S1664	L1657R	1657	Missense	distal	-7	no	8.205	8.223	EPSD	COSMIC	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	P25054	APC	P49841	GSK3B	S1664	S1658R	1658	Missense	distal	-6	no	8.205	8.148	EPSD	COSMIC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	P25054	APC	P49841	GSK3B	S1664	S1664Y	1664	Missense	central	0	yes	8.205	0.000	EPSD	COSMIC	6.007	Loss
CMGC_GSK_GSK3B_ST	P25054	APC	P49841	GSK3B	S1664	P1665T	1665	Missense	proximal	1	no	8.205	5.014	EPSD	COSMIC	6.007	Loss
CMGC_GSK_GSK3B_ST	P25054	APC	P49841	GSK3B	S1754	A1759E	1759	Missense	distal	5	no	6.118	6.501	EPSD	COSMIC	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	P25054	APC	P49841	GSK3B	S1754	P1760R	1760	Missense	distal	6	no	6.118	6.111	EPSD	COSMIC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	P25054	APC	P49841	GSK3B	S1754	D1748N	1748	Missense	distal	-6	no	6.118	6.140	EPSD	COSMIC	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	P25054	APC	P49841	GSK3B	S1754	S1756C	1756	Missense	proximal	2	no	6.118	5.625	EPSD	COSMIC	6.007	Loss
CMGC_GSK_GSK3B_ST	P25054	APC	P49841	GSK3B	T1847	E1850K	1850	Missense	distal	3	no	6.378	6.270	EPSD	COSMIC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	P25054	APC	P49841	GSK3B	T1847	D1841H	1841	Missense	distal	-6	no	6.378	6.369	EPSD	COSMIC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	P25054	APC	P49841	GSK3B	T1847	H1845N	1845	Missense	proximal	-2	no	6.378	6.254	EPSD	COSMIC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	P25054	APC	P49841	GSK3B	T1847	S1842L	1842	Missense	distal	-5	no	6.378	6.486	EPSD	COSMIC	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	P25054	APC	P49841	GSK3B	T1847	P1843S	1843	Missense	distal	-4	no	6.378	6.941	EPSD	COSMIC	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	P25054	APC	P49841	GSK3B	T1847	G1851E	1851	Missense	distal	4	no	6.378	7.600	EPSD	COSMIC	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	P25054	APC	P49841	GSK3B	T1847	H1845Y	1845	Missense	proximal	-2	no	6.378	6.164	EPSD	COSMIC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	P25054	APC	P49841	GSK3B	T1847	H1845Q	1845	Missense	proximal	-2	no	6.378	6.438	EPSD	COSMIC	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	P25054	APC	P49841	GSK3B	T1852	E1850K	1850	Missense	proximal	-2	no	6.569	6.537	EPSD	COSMIC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	P25054	APC	P49841	GSK3B	T1852	H1845N	1845	Missense	distal	-7	no	6.569	6.557	EPSD	COSMIC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	P25054	APC	P49841	GSK3B	T1852	G1851E	1851	Missense	proximal	-1	no	6.569	6.550	EPSD	COSMIC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	P25054	APC	P49841	GSK3B	T1852	H1845Y	1845	Missense	distal	-7	no	6.569	6.579	EPSD	COSMIC	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	P25054	APC	P49841	GSK3B	T1852	S1857L	1857	Missense	distal	5	no	6.569	6.242	EPSD	COSMIC;GDSC;CCLE	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	P25054	APC	P49841	GSK3B	T1852	H1845Q	1845	Missense	distal	-7	no	6.569	6.566	EPSD	COSMIC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	P25054	APC	P49841	GSK3B	T1852	C1855R	1855	Missense	distal	3	no	6.569	6.413	EPSD	COSMIC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	P25054	APC	P49841	GSK3B	S1857	S1864Y	1864	Missense	distal	7	no	8.480	8.922	EPSD	COSMIC;GDSC;CCLE	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	P25054	APC	P49841	GSK3B	S1857	E1850K	1850	Missense	distal	-7	no	8.480	8.468	EPSD	COSMIC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	P25054	APC	P49841	GSK3B	S1857	R1858Q	1858	Missense	proximal	1	no	8.480	7.531	EPSD	COSMIC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	P25054	APC	P49841	GSK3B	S1857	S1864F	1864	Missense	distal	7	no	8.480	8.557	EPSD	COSMIC	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	P25054	APC	P49841	GSK3B	S1857	G1851E	1851	Missense	distal	-6	no	8.480	8.402	EPSD	COSMIC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	P25054	APC	P49841	GSK3B	S1857	S1861F	1861	Missense	distal	4	no	8.480	4.865	EPSD	COSMIC	6.007	Loss
CMGC_GSK_GSK3B_ST	P25054	APC	P49841	GSK3B	S1857	S1857L	1857	Missense	central	0	yes	8.480	0.000	EPSD	COSMIC;GDSC;CCLE	6.007	Loss
CMGC_GSK_GSK3B_ST	P25054	APC	P49841	GSK3B	S1857	L1862F	1862	Missense	distal	5	no	8.480	8.139	EPSD	COSMIC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	P25054	APC	P49841	GSK3B	S1857	C1855R	1855	Missense	proximal	-2	no	8.480	8.676	EPSD	COSMIC	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	P25054	APC	P49841	GSK3B	S1861	D1868H	1868	Missense	distal	7	no	5.986	6.558	EPSD	COSMIC	6.007	Gain
CMGC_GSK_GSK3B_ST	P25054	APC	P49841	GSK3B	S1864	L1865P	1865	Missense	proximal	1	no	3.569	6.429	EPSD	COSMIC	6.007	Gain
CMGC_GSK_GSK3B_ST	P25054	APC	P49841	GSK3B	S1896	H1897P	1897	Missense	proximal	1	no	2.653	6.353	EPSD	COSMIC	6.007	Gain
CMGC_GSK_GSK3B_ST	P25054	APC	P49841	GSK3B	S2022	R2023K	2023	Missense	proximal	1	no	6.546	5.320	EPSD	COSMIC	6.007	Loss
CMGC_GSK_GSK3B_ST	P25054	APC	P49841	GSK3B	S2022	N2024K	2024	Missense	proximal	2	no	6.546	7.031	EPSD	COSMIC	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	P25054	APC	P49841	GSK3B	S2022	L2027P	2027	Missense	distal	5	no	6.546	7.827	EPSD	COSMIC	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	P25054	APC	P49841	GSK3B	S2022	R2023G	2023	Missense	proximal	1	no	6.546	5.672	EPSD	COSMIC	6.007	Loss
CMGC_GSK_GSK3B_ST	P25054	APC	P49841	GSK3B	S2022	R2023I	2023	Missense	proximal	1	no	6.546	4.984	EPSD	COSMIC	6.007	Loss
CMGC_GSK_GSK3B_ST	P25054	APC	P49841	GSK3B	S2022	P2018L	2018	Missense	distal	-4	no	6.546	5.759	EPSD	COSMIC	6.007	Loss
CMGC_GSK_GSK3B_ST	P25054	APC	P49841	GSK3B	S2054	K2050N	2050	Missense	distal	-4	no	6.313	5.880	EPSD	COSMIC	6.007	Loss
CMGC_GSK_GSK3B_ST	P25054	APC	P49841	GSK3B	S2054	N2060D	2060	Missense	distal	6	no	6.313	6.312	EPSD	COSMIC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	P25054	APC	P49841	GSK3B	S2054	D2059N	2059	Missense	distal	5	no	6.313	5.886	EPSD	COSMIC	6.007	Loss
CMGC_GSK_GSK3B_ST	P25054	APC	P49841	GSK3B	S2054	M2047I	2047	Missense	distal	-7	no	6.313	6.320	EPSD	COSMIC	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	P25054	APC	P49841	GSK3B	S2054	K2057R	2057	Missense	distal	3	no	6.313	6.069	EPSD	COSMIC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	P25054	APC	P49841	GSK3B	S2064	N2060D	2060	Missense	distal	-4	no	5.718	6.415	EPSD	COSMIC	6.007	Gain
CMGC_GSK_GSK3B_ST	P25054	APC	P49841	GSK3B	S2093	F2099C	2099	Missense	distal	6	no	6.880	6.879	EPSD	COSMIC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	P25054	APC	P49841	GSK3B	S2093	P2094L	2094	Missense	proximal	1	no	6.880	4.020	EPSD	COSMIC	6.007	Loss
CMGC_GSK_GSK3B_ST	P25054	APC	P49841	GSK3B	S2093	N2098S	2098	Missense	distal	5	no	6.880	7.201	EPSD	COSMIC	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	P25054	APC	P49841	GSK3B	S2093	S2093Y	2093	Missense	central	0	yes	6.880	0.000	EPSD	COSMIC	6.007	Loss
CMGC_GSK_GSK3B_ST	P25054	APC	P49841	GSK3B	S2093	L2092I	2092	Missense	proximal	-1	no	6.880	6.806	EPSD	COSMIC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	P25054	APC	P49841	GSK3B	S2130	S2125F	2125	Missense	distal	-5	no	5.715	6.274	EPSD	COSMIC	6.007	Gain
CMGC_GSK_GSK3B_ST	P25054	APC	P49841	GSK3B	S2130	R2126G	2126	Missense	distal	-4	no	5.715	6.473	EPSD	COSMIC	6.007	Gain
CMGC_GSK_GSK3B_ST	P25054	APC	P49841	GSK3B	S2130	A2128V	2128	Missense	proximal	-2	no	5.715	6.017	EPSD	COSMIC	6.007	Gain
CMGC_GSK_GSK3B_ST	P25054	APC	P49841	GSK3B	S2130	R2126S	2126	Missense	distal	-4	no	5.715	6.901	EPSD	COSMIC	6.007	Gain
CMGC_GSK_GSK3B_ST	P25054	APC	P49841	GSK3B	T2151	P2158R	2158	Missense	distal	7	no	5.826	6.327	EPSD	COSMIC	6.007	Gain
CMGC_GSK_GSK3B_ST	P25054	APC	P49841	GSK3B	S2174	I2167S	2167	Missense	distal	-7	no	6.229	6.201	EPSD	COSMIC;GDSC;CCLE	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	P25054	APC	P49841	GSK3B	S2174	P2170L	2170	Missense	distal	-4	no	6.229	5.442	EPSD	COSMIC	6.007	Loss
CMGC_GSK_GSK3B_ST	P25054	APC	P49841	GSK3B	S2174	K2173E	2173	Missense	proximal	-1	no	6.229	6.162	EPSD	COSMIC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	P25054	APC	P49841	GSK3B	S2174	E2172K	2172	Missense	proximal	-2	no	6.229	6.197	EPSD	COSMIC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	P25054	APC	P49841	GSK3B	S2174	S2174R	2174	Missense	central	0	yes	6.229	0.000	EPSD	COSMIC	6.007	Loss
CMGC_GSK_GSK3B_ST	P25054	APC	P49841	GSK3B	S2174	T2178N	2178	Missense	distal	4	no	6.229	3.487	EPSD	COSMIC	6.007	Loss
CMGC_GSK_GSK3B_ST	P25054	APC	P49841	GSK3B	S2240	S2241L	2241	Missense	proximal	1	no	6.762	7.747	EPSD	COSMIC	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	P25054	APC	P49841	GSK3B	S2240	V2236A	2236	Missense	distal	-4	no	6.762	6.836	EPSD	COSMIC	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	P25054	APC	P49841	GSK3B	S2240	V2246I	2246	Missense	distal	6	no	6.762	6.772	EPSD	COSMIC	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	P25054	APC	P49841	GSK3B	S2240	P2234L	2234	Missense	distal	-6	no	6.762	6.740	EPSD	COSMIC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	P25054	APC	P49841	GSK3B	S2240	S2247P	2247	Missense	distal	7	no	6.762	6.699	EPSD	COSMIC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	P25054	APC	P49841	GSK3B	S2240	R2237L	2237	Missense	distal	-3	no	6.762	6.603	EPSD	COSMIC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	P25054	APC	P49841	GSK3B	S2240	S2242G	2242	Missense	proximal	2	no	6.762	6.504	EPSD	COSMIC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	P25054	APC	P49841	GSK3B	T2243	S2241L	2241	Missense	proximal	-2	no	6.497	6.423	EPSD	COSMIC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	P25054	APC	P49841	GSK3B	T2243	V2236A	2236	Missense	distal	-7	no	6.497	6.498	EPSD	COSMIC	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	P25054	APC	P49841	GSK3B	T2243	V2246I	2246	Missense	distal	3	no	6.497	6.285	EPSD	COSMIC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	P25054	APC	P49841	GSK3B	T2243	S2247P	2247	Missense	distal	4	no	6.497	3.526	EPSD	COSMIC	6.007	Loss
CMGC_GSK_GSK3B_ST	P25054	APC	P49841	GSK3B	T2243	R2237L	2237	Missense	distal	-6	no	6.497	6.553	EPSD	COSMIC	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	P25054	APC	P49841	GSK3B	T2243	S2242G	2242	Missense	proximal	-1	no	6.497	6.504	EPSD	COSMIC	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	P25054	APC	P49841	GSK3B	T2243	K2249Q	2249	Missense	distal	6	no	6.497	6.499	EPSD	COSMIC	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	P25054	APC	P49841	GSK3B	S2244	V2246I	2246	Missense	proximal	2	no	5.821	6.150	EPSD	COSMIC	6.007	Gain
CMGC_GSK_GSK3B_ST	P25054	APC	P49841	GSK3B	S2244	K2249Q	2249	Missense	distal	5	no	5.821	6.357	EPSD	COSMIC	6.007	Gain
CMGC_GSK_GSK3B_ST	P25054	APC	P49841	GSK3B	T2255	L2253H	2253	Missense	proximal	-2	no	6.155	6.123	EPSD	COSMIC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	P25054	APC	P49841	GSK3B	T2255	P2252H	2252	Missense	distal	-3	no	6.155	6.383	EPSD	COSMIC	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	P25054	APC	P49841	GSK3B	T2255	K2249Q	2249	Missense	distal	-6	no	6.155	6.213	EPSD	COSMIC	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	P25054	APC	P49841	GSK3B	S2258	L2253H	2253	Missense	distal	-5	no	7.079	7.137	EPSD	COSMIC	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	P25054	APC	P49841	GSK3B	S2258	P2252H	2252	Missense	distal	-6	no	7.079	7.024	EPSD	COSMIC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	P25054	APC	P49841	GSK3B	S2260	T2266I	2266	Missense	distal	6	no	6.088	6.085	EPSD	COSMIC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	P25054	APC	P49841	GSK3B	S2260	T2266S	2266	Missense	distal	6	no	6.088	6.085	EPSD	COSMIC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	P25054	APC	P49841	GSK3B	S2260	L2253H	2253	Missense	distal	-7	no	6.088	6.106	EPSD	COSMIC	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	P25054	APC	P49841	GSK3B	S2270	T2266I	2266	Missense	distal	-4	no	6.995	4.847	EPSD	COSMIC	6.007	Loss
CMGC_GSK_GSK3B_ST	P25054	APC	P49841	GSK3B	S2270	T2266S	2266	Missense	distal	-4	no	6.995	7.330	EPSD	COSMIC	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	P25054	APC	P49841	GSK3B	S2270	T2268S	2268	Missense	proximal	-2	no	6.995	6.968	EPSD	COSMIC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	P25054	APC	P49841	GSK3B	S2270	S2277F	2277	Missense	distal	7	no	6.995	7.072	EPSD	COSMIC	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	P25054	APC	P49841	GSK3B	S2270	A2274V	2274	Missense	distal	4	no	6.995	7.017	EPSD	COSMIC;GDSC	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	P25054	APC	P49841	GSK3B	S2270	S2270C	2270	Missense	central	0	yes	6.995	0.000	EPSD	COSMIC	6.007	Loss
CMGC_GSK_GSK3B_ST	P25054	APC	P49841	GSK3B	S2280	P2284S	2284	Missense	distal	4	no	3.182	6.153	EPSD	COSMIC	6.007	Gain
CMGC_GSK_GSK3B_ST	P25054	APC	P49841	GSK3B	S2283	V2285A	2285	Missense	proximal	2	no	6.401	6.678	EPSD	COSMIC	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	P25054	APC	P49841	GSK3B	S2283	S2277F	2277	Missense	distal	-6	no	6.401	6.348	EPSD	COSMIC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	P25054	APC	P49841	GSK3B	S2283	A2286S	2286	Missense	distal	3	no	6.401	6.738	EPSD	COSMIC	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	P25054	APC	P49841	GSK3B	S2283	V2285I	2285	Missense	proximal	2	no	6.401	6.731	EPSD	COSMIC	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	P25054	APC	P49841	GSK3B	S2283	P2284S	2284	Missense	proximal	1	no	6.401	2.556	EPSD	COSMIC	6.007	Loss
CMGC_GSK_GSK3B_ST	P25054	APC	P49841	GSK3B	S2300	S2307T	2307	Missense	distal	7	no	9.383	9.324	EPSD	COSMIC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	P25054	APC	P49841	GSK3B	S2300	S2296N	2296	Missense	distal	-4	no	9.383	8.085	EPSD	COSMIC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	P25054	APC	P49841	GSK3B	S2300	G2303R	2303	Missense	distal	3	no	9.383	8.968	EPSD	COSMIC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	P25054	APC	P49841	GSK3B	S2300	S2302L	2302	Missense	proximal	2	no	9.383	9.443	EPSD	COSMIC	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	P25054	APC	P49841	GSK3B	S2300	K2297E	2297	Missense	distal	-3	no	9.383	9.373	EPSD	COSMIC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	P25054	APC	P49841	GSK3B	S2300	G2294R	2294	Missense	distal	-6	no	9.383	9.309	EPSD	COSMIC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	P25054	APC	P49841	GSK3B	S2300	S2295L	2295	Missense	distal	-5	no	9.383	9.492	EPSD	COSMIC	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	P25054	APC	P49841	GSK3B	S2300	G2293C	2293	Missense	distal	-7	no	9.383	9.408	EPSD	COSMIC	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	P25054	APC	P49841	GSK3B	S2304	S2307T	2307	Missense	distal	3	no	10.068	10.035	EPSD	COSMIC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	P25054	APC	P49841	GSK3B	S2304	G2303R	2303	Missense	proximal	-1	no	10.068	9.924	EPSD	COSMIC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	P25054	APC	P49841	GSK3B	S2304	S2302L	2302	Missense	proximal	-2	no	10.068	9.994	EPSD	COSMIC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	P25054	APC	P49841	GSK3B	S2304	K2297E	2297	Missense	distal	-7	no	10.068	10.079	EPSD	COSMIC	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	P25054	APC	P49841	GSK3B	S2304	P2309L	2309	Missense	distal	5	no	10.068	8.787	EPSD	COSMIC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	P25054	APC	P49841	GSK3B	S2304	R2311T	2311	Missense	distal	7	no	10.068	9.571	EPSD	COSMIC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	P25054	APC	P49841	GSK3B	S2307	G2303R	2303	Missense	distal	-4	no	7.358	6.599	EPSD	COSMIC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	P25054	APC	P49841	GSK3B	S2307	S2302L	2302	Missense	distal	-5	no	7.358	7.467	EPSD	COSMIC	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	P25054	APC	P49841	GSK3B	S2307	A2313T	2313	Missense	distal	6	no	7.358	7.362	EPSD	COSMIC	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	P25054	APC	P49841	GSK3B	S2307	P2309L	2309	Missense	proximal	2	no	7.358	6.974	EPSD	COSMIC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	P25054	APC	P49841	GSK3B	S2307	R2311T	2311	Missense	distal	4	no	7.358	9.527	EPSD	COSMIC	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	P25054	APC	P49841	GSK3B	T2308	S2307T	2307	Missense	proximal	-1	no	6.717	6.642	EPSD	COSMIC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	P25054	APC	P49841	GSK3B	T2308	G2303R	2303	Missense	distal	-5	no	6.717	6.949	EPSD	COSMIC	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	P25054	APC	P49841	GSK3B	T2308	S2302L	2302	Missense	distal	-6	no	6.717	6.716	EPSD	COSMIC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	P25054	APC	P49841	GSK3B	T2308	A2313T	2313	Missense	distal	5	no	6.717	6.769	EPSD	COSMIC	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	P25054	APC	P49841	GSK3B	T2308	P2309L	2309	Missense	proximal	1	no	6.717	3.857	EPSD	COSMIC	6.007	Loss
CMGC_GSK_GSK3B_ST	P25054	APC	P49841	GSK3B	T2308	R2311T	2311	Missense	distal	3	no	6.717	7.055	EPSD	COSMIC	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	P25054	APC	P49841	GSK3B	S2337	K2341N	2341	Missense	distal	4	no	7.677	7.269	EPSD	COSMIC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	P25054	APC	P49841	GSK3B	S2337	Q2344E	2344	Missense	distal	7	no	7.677	7.626	EPSD	COSMIC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	P25054	APC	P49841	GSK3B	T2348	S2355L	2355	Missense	distal	7	no	6.595	6.581	EPSD	COSMIC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	P25054	APC	P49841	GSK3B	T2348	K2341N	2341	Missense	distal	-7	no	6.595	6.580	EPSD	COSMIC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	P25054	APC	P49841	GSK3B	T2348	Q2344E	2344	Missense	distal	-4	no	6.595	6.827	EPSD	COSMIC	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	P25054	APC	P49841	GSK3B	T2348	T2348A	2348	Missense	central	0	yes	6.595	0.000	EPSD	COSMIC	6.007	Loss
CMGC_GSK_GSK3B_ST	P25054	APC	P49841	GSK3B	S2350	S2355L	2355	Missense	distal	5	no	7.290	6.963	EPSD	COSMIC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	P25054	APC	P49841	GSK3B	S2350	Q2344E	2344	Missense	distal	-6	no	7.290	7.233	EPSD	COSMIC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	P25054	APC	P49841	GSK3B	S2350	T2348A	2348	Missense	proximal	-2	no	7.290	6.928	EPSD	COSMIC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	P25054	APC	P49841	GSK3B	S2350	T2356I	2356	Missense	distal	6	no	7.290	7.287	EPSD	COSMIC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	P25054	APC	P49841	GSK3B	S2390	K2386M	2386	Missense	distal	-4	no	7.039	6.844	EPSD	COSMIC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	P25054	APC	P49841	GSK3B	S2390	K2386N	2386	Missense	distal	-4	no	7.039	6.606	EPSD	COSMIC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	P25054	APC	P49841	GSK3B	S2390	L2384I	2384	Missense	distal	-6	no	7.039	6.977	EPSD	COSMIC;CCLE	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	P25054	APC	P49841	GSK3B	S2390	P2392S	2392	Missense	proximal	2	no	7.039	6.595	EPSD	COSMIC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	P25054	APC	P49841	GSK3B	S2421	S2417Y	2417	Missense	distal	-4	no	6.129	5.329	EPSD	COSMIC	6.007	Loss
CMGC_GSK_GSK3B_ST	P25054	APC	P49841	GSK3B	S2421	E2428K	2428	Missense	distal	7	no	6.129	6.021	EPSD	COSMIC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	P25054	APC	P49841	GSK3B	S2421	T2422S	2422	Missense	proximal	1	no	6.129	5.475	EPSD	COSMIC	6.007	Loss
CMGC_GSK_GSK3B_ST	P25054	APC	P49841	GSK3B	S2421	E2415Q	2415	Missense	distal	-6	no	6.129	6.187	EPSD	COSMIC	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	P25054	APC	P49841	GSK3B	S2425	S2421T	2421	Missense	distal	-4	no	7.244	6.909	EPSD	COSMIC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	P25054	APC	P49841	GSK3B	S2425	D2430N	2430	Missense	distal	5	no	7.244	6.818	EPSD	COSMIC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	P25054	APC	P49841	GSK3B	S2425	E2428K	2428	Missense	distal	3	no	7.244	7.137	EPSD	COSMIC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	P25054	APC	P49841	GSK3B	S2425	T2422S	2422	Missense	distal	-3	no	7.244	7.219	EPSD	COSMIC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	P25054	APC	P49841	GSK3B	S2429	D2430N	2430	Missense	proximal	1	no	6.304	3.887	EPSD	COSMIC	6.007	Loss
CMGC_GSK_GSK3B_ST	P25054	APC	P49841	GSK3B	S2429	E2428K	2428	Missense	proximal	-1	no	6.304	6.370	EPSD	COSMIC	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	P25054	APC	P49841	GSK3B	S2429	T2422S	2422	Missense	distal	-7	no	6.304	6.277	EPSD	COSMIC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	P25054	APC	P49841	GSK3B	S2429	R2434I	2434	Missense	distal	5	no	6.304	5.321	EPSD	COSMIC	6.007	Loss
CMGC_GSK_GSK3B_ST	P25054	APC	P49841	GSK3B	S2449	A2447S	2447	Missense	proximal	-2	no	6.896	7.230	EPSD	COSMIC	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	P25054	APC	P49841	GSK3B	S2449	P2448L	2448	Missense	proximal	-1	no	6.896	6.764	EPSD	COSMIC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	P25054	APC	P49841	GSK3B	S2449	S2449N	2449	Missense	central	0	yes	6.896	0.000	EPSD	COSMIC	6.007	Loss
CMGC_GSK_GSK3B_ST	P25054	APC	P49841	GSK3B	S2449	A2447V	2447	Missense	proximal	-2	no	6.896	7.198	EPSD	COSMIC	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	P25054	APC	P49841	GSK3B	S2464	S2466F	2466	Missense	proximal	2	no	6.799	6.454	EPSD	COSMIC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	P25054	APC	P49841	GSK3B	S2464	P2467S	2467	Missense	distal	3	no	6.799	6.781	EPSD	COSMIC;GDSC;CCLE	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	P25054	APC	P49841	GSK3B	S2464	P2467T	2467	Missense	distal	3	no	6.799	6.749	EPSD	COSMIC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	P25054	APC	P49841	GSK3B	S2464	R2470G	2470	Missense	distal	6	no	6.799	6.800	EPSD	COSMIC	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	P25054	APC	P49841	GSK3B	S2464	R2470T	2470	Missense	distal	6	no	6.799	6.806	EPSD	COSMIC	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	P25054	APC	P49841	GSK3B	S2464	E2457G	2457	Missense	distal	-7	no	6.799	6.764	EPSD	COSMIC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	P25054	APC	P49841	GSK3B	S2464	E2457D	2457	Missense	distal	-7	no	6.799	6.769	EPSD	COSMIC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	P25054	APC	P49841	GSK3B	S2464	E2458V	2458	Missense	distal	-6	no	6.799	6.794	EPSD	COSMIC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	P25054	APC	P49841	GSK3B	S2464	R2470K	2470	Missense	distal	6	no	6.799	6.798	EPSD	COSMIC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	P25054	APC	P49841	GSK3B	S2464	S2466Y	2466	Missense	proximal	2	no	6.799	6.567	EPSD	COSMIC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	P25054	APC	P49841	GSK3B	S2464	E2463D	2463	Missense	proximal	-1	no	6.799	6.750	EPSD	COSMIC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	P25054	APC	P49841	GSK3B	S2466	S2466F	2466	Missense	central	0	yes	7.295	0.000	EPSD	COSMIC	6.007	Loss
CMGC_GSK_GSK3B_ST	P25054	APC	P49841	GSK3B	S2466	P2467S	2467	Missense	proximal	1	no	7.295	3.450	EPSD	COSMIC;GDSC;CCLE	6.007	Loss
CMGC_GSK_GSK3B_ST	P25054	APC	P49841	GSK3B	S2466	P2467T	2467	Missense	proximal	1	no	7.295	4.104	EPSD	COSMIC	6.007	Loss
CMGC_GSK_GSK3B_ST	P25054	APC	P49841	GSK3B	S2466	R2470G	2470	Missense	distal	4	no	7.295	7.090	EPSD	COSMIC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	P25054	APC	P49841	GSK3B	S2466	R2470T	2470	Missense	distal	4	no	7.295	9.464	EPSD	COSMIC	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	P25054	APC	P49841	GSK3B	S2466	R2470K	2470	Missense	distal	4	no	7.295	7.130	EPSD	COSMIC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	P25054	APC	P49841	GSK3B	S2466	S2466Y	2466	Missense	central	0	yes	7.295	0.000	EPSD	COSMIC	6.007	Loss
CMGC_GSK_GSK3B_ST	P25054	APC	P49841	GSK3B	S2466	S2473Y	2473	Missense	distal	7	no	7.295	7.737	EPSD	COSMIC	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	P25054	APC	P49841	GSK3B	S2466	E2463D	2463	Missense	distal	-3	no	7.295	7.328	EPSD	COSMIC	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	P25054	APC	P49841	GSK3B	S2469	S2466F	2466	Missense	distal	-3	no	7.641	7.708	EPSD	COSMIC	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	P25054	APC	P49841	GSK3B	S2469	P2467S	2467	Missense	proximal	-2	no	7.641	7.385	EPSD	COSMIC;GDSC;CCLE	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	P25054	APC	P49841	GSK3B	S2469	P2467T	2467	Missense	proximal	-2	no	7.641	7.412	EPSD	COSMIC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	P25054	APC	P49841	GSK3B	S2469	R2470G	2470	Missense	proximal	1	no	7.641	6.767	EPSD	COSMIC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	P25054	APC	P49841	GSK3B	S2469	R2470T	2470	Missense	proximal	1	no	7.641	6.770	EPSD	COSMIC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	P25054	APC	P49841	GSK3B	S2469	T2475A	2475	Missense	distal	6	no	7.641	7.637	EPSD	COSMIC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	P25054	APC	P49841	GSK3B	S2469	R2470K	2470	Missense	proximal	1	no	7.641	6.415	EPSD	COSMIC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	P25054	APC	P49841	GSK3B	S2469	S2466Y	2466	Missense	distal	-3	no	7.641	7.781	EPSD	COSMIC	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	P25054	APC	P49841	GSK3B	S2469	S2473Y	2473	Missense	distal	4	no	7.641	4.128	EPSD	COSMIC	6.007	Loss
CMGC_GSK_GSK3B_ST	P25054	APC	P49841	GSK3B	S2469	E2463D	2463	Missense	distal	-6	no	7.641	7.678	EPSD	COSMIC	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	P25054	APC	P49841	GSK3B	S2473	S2466F	2466	Missense	distal	-7	no	10.333	10.343	EPSD	COSMIC	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	P25054	APC	P49841	GSK3B	S2473	P2467S	2467	Missense	distal	-6	no	10.333	10.312	EPSD	COSMIC;GDSC;CCLE	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	P25054	APC	P49841	GSK3B	S2473	P2467T	2467	Missense	distal	-6	no	10.333	10.254	EPSD	COSMIC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	P25054	APC	P49841	GSK3B	S2473	R2470G	2470	Missense	distal	-3	no	10.333	10.160	EPSD	COSMIC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	P25054	APC	P49841	GSK3B	S2473	R2470T	2470	Missense	distal	-3	no	10.333	10.189	EPSD	COSMIC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	P25054	APC	P49841	GSK3B	S2473	T2475A	2475	Missense	proximal	2	no	10.333	10.214	EPSD	COSMIC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	P25054	APC	P49841	GSK3B	S2473	R2470K	2470	Missense	distal	-3	no	10.333	10.188	EPSD	COSMIC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	P25054	APC	P49841	GSK3B	S2473	A2479V	2479	Missense	distal	6	no	10.333	10.325	EPSD	COSMIC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	P25054	APC	P49841	GSK3B	S2473	S2466Y	2466	Missense	distal	-7	no	10.333	10.361	EPSD	COSMIC	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	P25054	APC	P49841	GSK3B	S2473	S2473Y	2473	Missense	central	0	yes	10.333	0.000	EPSD	COSMIC	6.007	Loss
CMGC_GSK_GSK3B_ST	P25054	APC	P49841	GSK3B	S2512	D2519Y	2519	Missense	distal	7	no	6.003	6.391	EPSD	COSMIC	6.007	Gain
CMGC_GSK_GSK3B_ST	P25054	APC	P49841	GSK3B	S2512	P2508S	2508	Missense	distal	-4	no	6.003	6.567	EPSD	COSMIC	6.007	Gain
CMGC_GSK_GSK3B_ST	P25054	APC	P49841	GSK3B	S2531	R2530W	2530	Missense	proximal	-1	no	6.477	6.589	EPSD	COSMIC	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	P25054	APC	P49841	GSK3B	S2531	S2533F	2533	Missense	proximal	2	no	6.477	6.132	EPSD	COSMIC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	P25054	APC	P49841	GSK3B	S2531	I2528V	2528	Missense	distal	-3	no	6.477	6.531	EPSD	COSMIC	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	P25054	APC	P49841	GSK3B	S2531	P2536S	2536	Missense	distal	5	no	6.477	5.523	EPSD	COSMIC	6.007	Loss
CMGC_GSK_GSK3B_ST	P25054	APC	P49841	GSK3B	S2531	D2527N	2527	Missense	distal	-4	no	6.477	5.780	EPSD	COSMIC	6.007	Loss
CMGC_GSK_GSK3B_ST	P25054	APC	P49841	GSK3B	S2531	P2536T	2536	Missense	distal	5	no	6.477	5.500	EPSD	COSMIC	6.007	Loss
CMGC_GSK_GSK3B_ST	P25054	APC	P49841	GSK3B	S2533	I2528V	2528	Missense	distal	-5	no	5.943	6.050	EPSD	COSMIC	6.007	Gain
CMGC_GSK_GSK3B_ST	P25054	APC	P49841	GSK3B	S2535	R2530W	2530	Missense	distal	-5	no	10.565	10.308	EPSD	COSMIC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	P25054	APC	P49841	GSK3B	S2535	S2533F	2533	Missense	proximal	-2	no	10.565	10.234	EPSD	COSMIC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	P25054	APC	P49841	GSK3B	S2535	I2528V	2528	Missense	distal	-7	no	10.565	10.558	EPSD	COSMIC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	P25054	APC	P49841	GSK3B	S2535	P2536S	2536	Missense	proximal	1	no	10.565	6.720	EPSD	COSMIC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	P25054	APC	P49841	GSK3B	S2535	N2542S	2542	Missense	distal	7	no	10.565	10.442	EPSD	COSMIC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	P25054	APC	P49841	GSK3B	S2535	P2536T	2536	Missense	proximal	1	no	10.565	7.374	EPSD	COSMIC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	P25054	APC	P49841	GSK3B	T2563	W2564C	2564	Missense	proximal	1	no	7.337	5.117	EPSD	COSMIC	6.007	Loss
CMGC_GSK_GSK3B_ST	P25054	APC	P49841	GSK3B	T2563	R2560Q	2560	Missense	distal	-3	no	7.337	7.199	EPSD	COSMIC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	P25054	APC	P49841	GSK3B	T2563	L2558H	2558	Missense	distal	-5	no	7.337	7.395	EPSD	COSMIC	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	P25054	APC	P49841	GSK3B	T2563	R2565I	2565	Missense	proximal	2	no	7.337	7.380	EPSD	COSMIC	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	P25054	APC	P49841	GSK3B	T2563	S2562G	2562	Missense	proximal	-1	no	7.337	7.344	EPSD	COSMIC;CCLE	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	P25054	APC	P49841	GSK3B	T2563	R2565K	2565	Missense	proximal	2	no	7.337	7.272	EPSD	COSMIC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	P25054	APC	P49841	GSK3B	T2563	R2566I	2566	Missense	distal	3	no	7.337	7.288	EPSD	COSMIC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	P25054	APC	P49841	GSK3B	T2563	S2570L	2570	Missense	distal	7	no	7.337	7.323	EPSD	COSMIC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	P25054	APC	P49841	GSK3B	T2563	S2562C	2562	Missense	proximal	-1	no	7.337	7.301	EPSD	COSMIC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	P25054	APC	P49841	GSK3B	T2563	S2569R	2569	Missense	distal	6	no	7.337	7.333	EPSD	COSMIC;GDSC;CCLE	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	P25054	APC	P49841	GSK3B	T2567	S2562G	2562	Missense	distal	-5	no	5.736	6.202	EPSD	COSMIC;CCLE	6.007	Gain
CMGC_GSK_GSK3B_ST	P25054	APC	P49841	GSK3B	T2567	S2562C	2562	Missense	distal	-5	no	5.736	6.255	EPSD	COSMIC	6.007	Gain
CMGC_GSK_GSK3B_ST	P25054	APC	P49841	GSK3B	S2621	Q2628H	2628	Missense	distal	7	no	9.358	9.894	EPSD	COSMIC	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	P25054	APC	P49841	GSK3B	S2621	S2627F	2627	Missense	distal	6	no	9.358	9.346	EPSD	COSMIC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	P25054	APC	P49841	GSK3B	S2621	P2622S	2622	Missense	proximal	1	no	9.358	5.513	EPSD	COSMIC	6.007	Loss
CMGC_GSK_GSK3B_ST	P25054	APC	P49841	GSK3B	S2621	S2621F	2621	Missense	central	0	yes	9.358	0.000	EPSD	COSMIC	6.007	Loss
CMGC_GSK_GSK3B_ST	P25054	APC	P49841	GSK3B	S2621	P2622L	2622	Missense	proximal	1	no	9.358	6.498	EPSD	COSMIC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	P25054	APC	P49841	GSK3B	S2621	S2625N	2625	Missense	distal	4	no	9.358	5.748	EPSD	COSMIC	6.007	Loss
CMGC_GSK_GSK3B_ST	P25054	APC	P49841	GSK3B	S2625	Q2628H	2628	Missense	distal	3	no	6.567	6.576	EPSD	COSMIC	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	P25054	APC	P49841	GSK3B	S2625	S2631F	2631	Missense	distal	6	no	6.567	6.555	EPSD	COSMIC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	P25054	APC	P49841	GSK3B	S2625	S2627F	2627	Missense	proximal	2	no	6.567	6.222	EPSD	COSMIC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	P25054	APC	P49841	GSK3B	S2625	P2622S	2622	Missense	distal	-3	no	6.567	6.684	EPSD	COSMIC	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	P25054	APC	P49841	GSK3B	S2625	S2621F	2621	Missense	distal	-4	no	6.567	5.413	EPSD	COSMIC	6.007	Loss
CMGC_GSK_GSK3B_ST	P25054	APC	P49841	GSK3B	S2625	P2622L	2622	Missense	distal	-3	no	6.567	6.693	EPSD	COSMIC	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	P25054	APC	P49841	GSK3B	S2625	S2625N	2625	Missense	central	0	yes	6.567	0.000	EPSD	COSMIC	6.007	Loss
CMGC_GSK_GSK3B_ST	P25054	APC	P49841	GSK3B	S2627	Q2628H	2628	Missense	proximal	1	no	7.373	6.941	EPSD	COSMIC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	P25054	APC	P49841	GSK3B	S2627	G2633S	2633	Missense	distal	6	no	7.373	7.376	EPSD	COSMIC	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	P25054	APC	P49841	GSK3B	S2627	S2631F	2631	Missense	distal	4	no	7.373	3.759	EPSD	COSMIC	6.007	Loss
CMGC_GSK_GSK3B_ST	P25054	APC	P49841	GSK3B	S2627	S2627F	2627	Missense	central	0	yes	7.373	0.000	EPSD	COSMIC	6.007	Loss
CMGC_GSK_GSK3B_ST	P25054	APC	P49841	GSK3B	S2627	P2622S	2622	Missense	distal	-5	no	7.373	7.530	EPSD	COSMIC	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	P25054	APC	P49841	GSK3B	S2627	S2621F	2621	Missense	distal	-6	no	7.373	7.320	EPSD	COSMIC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	P25054	APC	P49841	GSK3B	S2627	P2622L	2622	Missense	distal	-5	no	7.373	7.639	EPSD	COSMIC	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	P25054	APC	P49841	GSK3B	S2627	S2625N	2625	Missense	proximal	-2	no	7.373	7.145	EPSD	COSMIC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	P25054	APC	P49841	GSK3B	T2629	G2633S	2633	Missense	distal	4	no	2.813	6.056	EPSD	COSMIC	6.007	Gain
CMGC_GSK_GSK3B_ST	P25054	APC	P49841	GSK3B	T2679	S2685G	2685	Missense	distal	6	no	6.363	6.360	EPSD	COSMIC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	P25054	APC	P49841	GSK3B	T2679	V2682M	2682	Missense	distal	3	no	6.363	6.380	EPSD	COSMIC	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	P25054	APC	P49841	GSK3B	T2679	S2674F	2674	Missense	distal	-5	no	6.363	6.923	EPSD	COSMIC	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	P25054	APC	P49841	GSK3B	S2763	S2766N	2766	Missense	distal	3	no	6.296	6.345	EPSD	COSMIC	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	P25054	APC	P49841	GSK3B	S2763	S2763N	2763	Missense	central	0	yes	6.296	0.000	EPSD	COSMIC	6.007	Loss
CMGC_GSK_GSK3B_ST	P25054	APC	P49841	GSK3B	S2763	T2760A	2760	Missense	distal	-3	no	6.296	6.292	EPSD	COSMIC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	P25054	APC	P49841	GSK3B	S2763	S2764Y	2764	Missense	proximal	1	no	6.296	6.823	EPSD	COSMIC	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	P25054	APC	P49841	GSK3B	S2767	S2766N	2766	Missense	proximal	-1	no	8.352	8.414	EPSD	COSMIC	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	P25054	APC	P49841	GSK3B	S2767	S2772P	2772	Missense	distal	5	no	8.352	9.306	EPSD	COSMIC	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	P25054	APC	P49841	GSK3B	S2767	S2763N	2763	Missense	distal	-4	no	8.352	7.055	EPSD	COSMIC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	P25054	APC	P49841	GSK3B	S2767	T2760A	2760	Missense	distal	-7	no	8.352	8.348	EPSD	COSMIC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	P25054	APC	P49841	GSK3B	S2767	S2764Y	2764	Missense	distal	-3	no	8.352	8.492	EPSD	COSMIC	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	P25054	APC	P49841	GSK3B	S2768	S2766N	2766	Missense	proximal	-2	no	7.195	6.967	EPSD	COSMIC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	P25054	APC	P49841	GSK3B	S2768	S2772P	2772	Missense	distal	4	no	7.195	4.224	EPSD	COSMIC	6.007	Loss
CMGC_GSK_GSK3B_ST	P25054	APC	P49841	GSK3B	S2768	S2763N	2763	Missense	distal	-5	no	7.195	6.903	EPSD	COSMIC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	P25054	APC	P49841	GSK3B	S2768	S2764Y	2764	Missense	distal	-4	no	7.195	6.395	EPSD	COSMIC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	P25054	APC	P49841	GSK3B	S2771	S2772P	2772	Missense	proximal	1	no	3.587	7.432	EPSD	COSMIC	6.007	Gain
CMGC_GSK_GSK3B_ST	P25054	APC	P49841	GSK3B	S2772	S2766N	2766	Missense	distal	-6	no	9.633	9.631	EPSD	COSMIC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	P25054	APC	P49841	GSK3B	S2772	S2772P	2772	Missense	central	0	yes	9.633	0.000	EPSD	COSMIC	6.007	Loss
CMGC_GSK_GSK3B_ST	P25054	APC	P49841	GSK3B	S2789	D2796N	2796	Missense	distal	7	no	8.105	8.174	EPSD	COSMIC	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	P25054	APC	P49841	GSK3B	S2789	P2790L	2790	Missense	proximal	1	no	8.105	5.245	EPSD	COSMIC	6.007	Loss
CMGC_GSK_GSK3B_ST	P25054	APC	P49841	GSK3B	S2789	S2793G	2793	Missense	distal	4	no	8.105	4.862	EPSD	COSMIC	6.007	Loss
CMGC_GSK_GSK3B_ST	P25054	APC	P49841	GSK3B	S2789	S2789I	2789	Missense	central	0	yes	8.105	0.000	EPSD	COSMIC	6.007	Loss
CMGC_GSK_GSK3B_ST	P25054	APC	P49841	GSK3B	S2789	N2787S	2787	Missense	proximal	-2	no	8.105	8.334	EPSD	COSMIC	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	P25054	APC	P49841	GSK3B	S2789	K2792R	2792	Missense	distal	3	no	8.105	7.861	EPSD	COSMIC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	P25054	APC	P49841	GSK3B	S2789	D2796G	2796	Missense	distal	7	no	8.105	8.070	EPSD	COSMIC;GDSC;CCLE	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	P25054	APC	P49841	GSK3B	S2789	R2791S	2791	Missense	proximal	2	no	8.105	8.087	EPSD	COSMIC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	P25054	APC	P49841	GSK3B	S2799	D2796N	2796	Missense	distal	-3	no	6.612	6.471	EPSD	COSMIC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	P25054	APC	P49841	GSK3B	S2799	S2803P	2803	Missense	distal	4	no	6.612	3.640	EPSD	COSMIC	6.007	Loss
CMGC_GSK_GSK3B_ST	P25054	APC	P49841	GSK3B	S2799	S2793G	2793	Missense	distal	-6	no	6.612	6.628	EPSD	COSMIC	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	P25054	APC	P49841	GSK3B	S2799	T2798A	2798	Missense	proximal	-1	no	6.612	6.532	EPSD	COSMIC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	P25054	APC	P49841	GSK3B	S2799	K2792R	2792	Missense	distal	-7	no	6.612	6.608	EPSD	COSMIC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	P25054	APC	P49841	GSK3B	S2799	D2796G	2796	Missense	distal	-3	no	6.612	6.561	EPSD	COSMIC;GDSC;CCLE	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	P25054	APC	P49841	GSK3B	S2803	D2796N	2796	Missense	distal	-7	no	6.932	6.935	EPSD	COSMIC	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	P25054	APC	P49841	GSK3B	S2803	S2803P	2803	Missense	central	0	yes	6.932	0.000	EPSD	COSMIC	6.007	Loss
CMGC_GSK_GSK3B_ST	P25054	APC	P49841	GSK3B	S2803	T2798A	2798	Missense	distal	-5	no	6.932	6.920	EPSD	COSMIC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	P25054	APC	P49841	GSK3B	S2803	D2796G	2796	Missense	distal	-7	no	6.932	6.927	EPSD	COSMIC;GDSC;CCLE	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	P25054	APC	P49841	GSK3B	S2822	T2820I	2820	Missense	proximal	-2	no	7.525	7.487	EPSD	COSMIC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	P25054	APC	P49841	GSK3B	S2822	S2825F	2825	Missense	distal	3	no	7.525	7.314	EPSD	COSMIC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	P25054	APC	P49841	GSK3B	S2822	D2821G	2821	Missense	proximal	-1	no	7.525	7.592	EPSD	COSMIC	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	P25054	APC	P49841	GSK3B	S2822	S2822N	2822	Missense	central	0	yes	7.525	0.000	EPSD	COSMIC	6.007	Loss
CMGC_GSK_GSK3B_ST	P25054	APC	P49841	GSK3B	S2822	R2816Q	2816	Missense	distal	-6	no	7.525	7.578	EPSD	COSMIC;GDSC;CCLE	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	P25054	APC	P49841	GSK3B	S2822	G2827E	2827	Missense	distal	5	no	7.525	7.791	EPSD	COSMIC	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	P25054	APC	P49841	GSK3B	S2822	E2824Q	2824	Missense	proximal	2	no	7.525	7.835	EPSD	COSMIC	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	P25054	APC	P49841	GSK3B	S2826	T2820I	2820	Missense	distal	-6	no	8.803	8.798	EPSD	COSMIC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	P25054	APC	P49841	GSK3B	S2826	S2825F	2825	Missense	proximal	-1	no	8.803	8.672	EPSD	COSMIC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	P25054	APC	P49841	GSK3B	S2826	D2821G	2821	Missense	distal	-5	no	8.803	8.996	EPSD	COSMIC	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	P25054	APC	P49841	GSK3B	S2826	S2822N	2822	Missense	distal	-4	no	8.803	7.505	EPSD	COSMIC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	P25054	APC	P49841	GSK3B	S2826	R2833C	2833	Missense	distal	7	no	8.803	8.757	EPSD	COSMIC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	P25054	APC	P49841	GSK3B	S2826	R2833H	2833	Missense	distal	7	no	8.803	8.991	EPSD	COSMIC	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	P25054	APC	P49841	GSK3B	S2826	G2827E	2827	Missense	proximal	1	no	8.803	8.163	EPSD	COSMIC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	P25054	APC	P49841	GSK3B	S2826	E2824Q	2824	Missense	proximal	-2	no	8.803	8.861	EPSD	COSMIC	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	P25054	APC	P49841	GSK3B	S2830	S2825F	2825	Missense	distal	-5	no	6.059	6.619	EPSD	COSMIC	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	P25054	APC	P49841	GSK3B	S2830	R2833C	2833	Missense	distal	3	no	6.059	6.214	EPSD	COSMIC	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	P25054	APC	P49841	GSK3B	S2830	R2833H	2833	Missense	distal	3	no	6.059	6.401	EPSD	COSMIC	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	P25054	APC	P49841	GSK3B	S2830	G2827E	2827	Missense	distal	-3	no	6.059	6.076	EPSD	COSMIC	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	P25054	APC	P49841	GSK3B	S2830	E2824Q	2824	Missense	distal	-6	no	6.059	6.116	EPSD	COSMIC	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	P25054	APC	P49841	GSK3B	S2830	G2836V	2836	Missense	distal	6	no	6.059	6.052	EPSD	COSMIC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	P25054	APC	P49841	GSK3B	S2837	T2841I	2841	Missense	distal	4	no	6.032	3.579	EPSD	COSMIC	6.007	Loss
CMGC_GSK_GSK3B_ST	P25054	APC	P49841	GSK3B	S2837	S2842T	2842	Missense	distal	5	no	6.032	6.010	EPSD	COSMIC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	P25054	APC	P49841	GSK3B	S2837	S2842Y	2842	Missense	distal	5	no	6.032	5.034	EPSD	COSMIC	6.007	Loss
CMGC_GSK_GSK3B_ST	P25054	APC	P49841	GSK3B	S2837	R2833C	2833	Missense	distal	-4	no	6.032	5.105	EPSD	COSMIC	6.007	Loss
CMGC_GSK_GSK3B_ST	P25054	APC	P49841	GSK3B	S2837	Y2838F	2838	Missense	proximal	1	no	6.032	5.120	EPSD	COSMIC	6.007	Loss
CMGC_GSK_GSK3B_ST	P25054	APC	P49841	GSK3B	S2837	R2833H	2833	Missense	distal	-4	no	6.032	6.131	EPSD	COSMIC	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	P25054	APC	P49841	GSK3B	S2837	G2836V	2836	Missense	proximal	-1	no	6.032	6.074	EPSD	COSMIC	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	Q99626	CDX2	P49841	GSK3B	S283	R276K	276	Missense	distal	-7	no	10.073	10.076	PhosphoSitePlus	COSMIC	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	Q99626	CDX2	P49841	GSK3B	S283	L288M	288	Missense	distal	5	no	10.073	10.261	PhosphoSitePlus	COSMIC	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	Q99626	CDX2	P49841	GSK3B	S287	S291A	291	Missense	distal	4	no	7.105	4.693	EPSD	COSMIC;GDSC;CCLE	6.007	Loss
CMGC_GSK_GSK3B_ST	Q99626	CDX2	P49841	GSK3B	S287	L288M	288	Missense	proximal	1	no	7.105	6.378	EPSD	COSMIC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	Q99626	CDX2	P49841	GSK3B	S287	S291L	291	Missense	distal	4	no	7.105	4.387	EPSD	COSMIC	6.007	Loss
CMGC_GSK_GSK3B_ST	Q99626	CDX2	P49841	GSK3B	S291	G298R	298	Missense	distal	7	no	7.019	7.437	EPSD	COSMIC	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	Q99626	CDX2	P49841	GSK3B	S291	S291A	291	Missense	central	0	yes	7.019	0.000	EPSD	COSMIC;GDSC;CCLE	6.007	Loss
CMGC_GSK_GSK3B_ST	Q99626	CDX2	P49841	GSK3B	S291	L288M	288	Missense	distal	-3	no	7.019	6.981	EPSD	COSMIC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	Q99626	CDX2	P49841	GSK3B	S291	S291L	291	Missense	central	0	yes	7.019	0.000	EPSD	COSMIC	6.007	Loss
CMGC_GSK_GSK3B_ST	Q99626	CDX2	P49841	GSK3B	S295	G298R	298	Missense	distal	3	no	7.049	6.634	EPSD	COSMIC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	Q99626	CDX2	P49841	GSK3B	S295	S291A	291	Missense	distal	-4	no	7.049	5.889	EPSD	COSMIC;GDSC;CCLE	6.007	Loss
CMGC_GSK_GSK3B_ST	Q99626	CDX2	P49841	GSK3B	S295	L288M	288	Missense	distal	-7	no	7.049	7.070	EPSD	COSMIC	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	Q99626	CDX2	P49841	GSK3B	S295	S291L	291	Missense	distal	-4	no	7.049	5.699	EPSD	COSMIC	6.007	Loss
CMGC_GSK_GSK3B_ST	P17812	CTPS1	P49841	GSK3B	S21	G17V	17	Missense	distal	-4	no	6.157	5.352	EPSD	COSMIC	6.007	Loss
CMGC_GSK_GSK3B_ST	P17812	CTPS1	P49841	GSK3B	S21	S21N	21	Missense	central	0	yes	6.157	0.000	EPSD	COSMIC	6.007	Loss
CMGC_GSK_GSK3B_ST	P17812	CTPS1	P49841	GSK3B	S210	P211T	211	Missense	proximal	1	no	7.051	3.860	EPSD	COSMIC	6.007	Loss
CMGC_GSK_GSK3B_ST	P17812	CTPS1	P49841	GSK3B	S210	R217M	217	Missense	distal	7	no	7.051	6.982	EPSD	COSMIC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	P17812	CTPS1	P49841	GSK3B	S210	C216R	216	Missense	distal	6	no	7.051	7.060	EPSD	COSMIC	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	P17812	CTPS1	P49841	GSK3B	S537	P533H	533	Missense	distal	-4	no	6.875	6.350	EPSD	COSMIC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	P17812	CTPS1	P49841	GSK3B	S562	C559Y	559	Missense	distal	-3	no	7.706	7.742	EPSD	COSMIC	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	P17812	CTPS1	P49841	GSK3B	S562	D565G	565	Missense	distal	3	no	7.706	7.655	EPSD	COSMIC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	P17812	CTPS1	P49841	GSK3B	S571	R570K	570	Missense	proximal	-1	no	8.812	9.004	PhosphoSitePlus	COSMIC	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	P17812	CTPS1	P49841	GSK3B	S571	D565G	565	Missense	distal	-6	no	8.812	8.853	PhosphoSitePlus	COSMIC	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	P17812	CTPS1	P49841	GSK3B	S574	R570K	570	Missense	distal	-4	no	7.509	7.831	EPSD	COSMIC	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	P17812	CTPS1	P49841	GSK3B	S575	R570K	570	Missense	distal	-5	no	9.324	8.827	EPSD	COSMIC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	P30291	WEE1	P49841	GSK3B	S45	G50S	50	Missense	distal	5	no	6.052	6.009	EPSD	COSMIC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	P30291	WEE1	P49841	GSK3B	S45	D52G	52	Missense	distal	7	no	6.052	6.017	EPSD	COSMIC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	P30291	WEE1	P49841	GSK3B	T49	G50S	50	Missense	proximal	1	no	7.005	6.354	EPSD	COSMIC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	P30291	WEE1	P49841	GSK3B	T49	D52G	52	Missense	distal	3	no	7.005	6.954	EPSD	COSMIC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	P30291	WEE1	P49841	GSK3B	T49	Q56E	56	Missense	distal	7	no	7.005	6.954	EPSD	COSMIC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	P30291	WEE1	P49841	GSK3B	S123	A129T	129	Missense	distal	6	no	11.485	11.489	EPSD	COSMIC	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	P30291	WEE1	P49841	GSK3B	S127	A129T	129	Missense	proximal	2	no	6.438	6.557	EPSD	COSMIC	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	P30291	WEE1	P49841	GSK3B	T190	K197T	197	Missense	distal	7	no	6.303	6.314	EPSD	COSMIC	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	P30291	WEE1	P49841	GSK3B	S293	K292N	292	Missense	proximal	-1	no	6.714	6.721	EPSD	COSMIC	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	P30291	WEE1	P49841	GSK3B	S480	F482L	482	Missense	proximal	2	no	6.217	6.621	EPSD	COSMIC	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	P30291	WEE1	P49841	GSK3B	S592	K588Q	588	Missense	distal	-4	no	6.089	6.124	EPSD	COSMIC	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	P30291	WEE1	P49841	GSK3B	S640	R639H	639	Missense	proximal	-1	no	5.932	6.018	EPSD	COSMIC	6.007	Gain
CMGC_GSK_GSK3B_ST	Q14195	DPYSL3	P49841	GSK3B	S308	P314L	314	Missense	distal	6	no	8.188	8.181	EPSD	COSMIC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	Q14195	DPYSL3	P49841	GSK3B	S308	T312N	312	Missense	distal	4	no	8.188	5.447	EPSD	COSMIC	6.007	Loss
CMGC_GSK_GSK3B_ST	Q14195	DPYSL3	P49841	GSK3B	S308	D315Y	315	Missense	distal	7	no	8.188	8.575	EPSD	COSMIC	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	Q14195	DPYSL3	P49841	GSK3B	S472	V478A	478	Missense	distal	6	no	7.743	7.751	EPSD	COSMIC	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	Q14195	DPYSL3	P49841	GSK3B	S472	R467C	467	Missense	distal	-5	no	7.743	7.565	EPSD	COSMIC;CCLE	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	Q14195	DPYSL3	P49841	GSK3B	S472	D476N	476	Missense	distal	4	no	7.743	6.556	EPSD	COSMIC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	Q14195	DPYSL3	P49841	GSK3B	S472	P473L	473	Missense	proximal	1	no	7.743	4.882	EPSD	COSMIC	6.007	Loss
CMGC_GSK_GSK3B_ST	Q14195	DPYSL3	P49841	GSK3B	T509	A516T	516	Missense	distal	7	no	9.218	8.811	EPSD;PhosphoSitePlus	COSMIC;GDSC;CCLE	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	Q14195	DPYSL3	P49841	GSK3B	T514	R520Q	520	Missense	distal	6	no	10.212	10.213	PhosphoSitePlus;EPSD	COSMIC	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	Q14195	DPYSL3	P49841	GSK3B	T514	A516T	516	Missense	proximal	2	no	10.212	10.331	PhosphoSitePlus;EPSD	COSMIC;GDSC;CCLE	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	Q14195	DPYSL3	P49841	GSK3B	S518	R525Q	525	Missense	distal	7	no	9.273	8.925	EPSD;PhosphoSitePlus	COSMIC;GDSC;CCLE	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	Q14195	DPYSL3	P49841	GSK3B	S518	R520Q	520	Missense	proximal	2	no	9.273	9.477	EPSD;PhosphoSitePlus	COSMIC	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	Q14195	DPYSL3	P49841	GSK3B	S518	A516T	516	Missense	proximal	-2	no	9.273	9.635	EPSD;PhosphoSitePlus	COSMIC;GDSC;CCLE	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	Q14195	DPYSL3	P49841	GSK3B	S522	R525Q	525	Missense	distal	3	no	7.516	7.849	EPSD	COSMIC;GDSC;CCLE	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	Q14195	DPYSL3	P49841	GSK3B	S522	R520Q	520	Missense	proximal	-2	no	7.516	7.586	EPSD	COSMIC	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	Q14195	DPYSL3	P49841	GSK3B	S522	A516T	516	Missense	distal	-6	no	7.516	7.447	EPSD	COSMIC;GDSC;CCLE	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	Q14195	DPYSL3	P49841	GSK3B	S522	P529H	529	Missense	distal	7	no	7.516	8.205	EPSD	COSMIC	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	Q14195	DPYSL3	P49841	GSK3B	T524	R520Q	520	Missense	distal	-4	no	5.724	6.082	EPSD	COSMIC	6.007	Gain
CMGC_GSK_GSK3B_ST	P54252	ATXN3	P49841	GSK3B	S256	S256R	256	Missense	central	0	yes	7.524	0.000	PhosphoSitePlus	COSMIC	6.007	Loss
CMGC_GSK_GSK3B_ST	P54252	ATXN3	P49841	GSK3B	S256	R250C	250	Missense	distal	-6	no	7.524	7.569	PhosphoSitePlus	COSMIC	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	P54252	ATXN3	P49841	GSK3B	S261	S265F	265	Missense	distal	4	no	6.373	2.759	EPSD	COSMIC	6.007	Loss
CMGC_GSK_GSK3B_ST	P54252	ATXN3	P49841	GSK3B	S261	S256R	256	Missense	distal	-5	no	6.373	7.071	EPSD	COSMIC	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	P54252	ATXN3	P49841	GSK3B	S265	S265F	265	Missense	central	0	yes	7.094	0.000	EPSD	COSMIC	6.007	Loss
CMGC_GSK_GSK3B_ST	P54252	ATXN3	P49841	GSK3B	S265	T271I	271	Missense	distal	6	no	7.094	7.092	EPSD	COSMIC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	P54252	ATXN3	P49841	GSK3B	S265	S272L	272	Missense	distal	7	no	7.094	7.080	EPSD	COSMIC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	Q15910	EZH2	P49841	GSK3B	S76	S75L	75	Missense	proximal	-1	no	7.147	7.072	EPSD	COSMIC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	Q15910	EZH2	P49841	GSK3B	S76	R78C	78	Missense	proximal	2	no	7.147	6.636	EPSD	COSMIC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	Q15910	EZH2	P49841	GSK3B	T261	I264T	264	Missense	distal	3	no	5.815	6.203	EPSD	COSMIC	6.007	Gain
CMGC_GSK_GSK3B_ST	Q15910	EZH2	P49841	GSK3B	T261	G266E	266	Missense	distal	5	no	5.815	6.082	EPSD	COSMIC	6.007	Gain
CMGC_GSK_GSK3B_ST	Q15910	EZH2	P49841	GSK3B	T261	G266R	266	Missense	distal	5	no	5.815	6.089	EPSD	COSMIC	6.007	Gain
CMGC_GSK_GSK3B_ST	Q15910	EZH2	P49841	GSK3B	T302	N304S	304	Missense	proximal	2	no	5.476	6.008	EPSD	COSMIC	6.007	Gain
CMGC_GSK_GSK3B_ST	Q15910	EZH2	P49841	GSK3B	T302	P298S	298	Missense	distal	-4	no	5.476	6.039	EPSD	COSMIC	6.007	Gain
CMGC_GSK_GSK3B_ST	Q15910	EZH2	P49841	GSK3B	T345	R342W	342	Missense	distal	-3	no	8.108	8.038	EPSD	COSMIC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	Q15910	EZH2	P49841	GSK3B	T345	R349C	349	Missense	distal	4	no	8.108	5.013	EPSD	COSMIC	6.007	Loss
CMGC_GSK_GSK3B_ST	Q15910	EZH2	P49841	GSK3B	T345	R342Q	342	Missense	distal	-3	no	8.108	7.969	EPSD	COSMIC;CCLE	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	Q15910	EZH2	P49841	GSK3B	T345	R342L	342	Missense	distal	-3	no	8.108	7.949	EPSD	COSMIC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	Q15910	EZH2	P49841	GSK3B	T345	A340T	340	Missense	distal	-5	no	8.108	8.120	EPSD	COSMIC;CCLE	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	Q15910	EZH2	P49841	GSK3B	T345	E341K	341	Missense	distal	-4	no	8.108	7.841	EPSD	COSMIC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	Q15910	EZH2	P49841	GSK3B	T345	L338F	338	Missense	distal	-7	no	8.108	8.118	EPSD	COSMIC	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	Q15910	EZH2	P49841	GSK3B	S363	P359S	359	Missense	distal	-4	no	8.182	8.746	PhosphoSitePlus;EPSD	COSMIC	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	Q15910	EZH2	P49841	GSK3B	S363	S363N	363	Missense	central	0	yes	8.182	0.000	PhosphoSitePlus;EPSD	COSMIC	6.007	Loss
CMGC_GSK_GSK3B_ST	Q15910	EZH2	P49841	GSK3B	S363	P368S	368	Missense	distal	5	no	8.182	7.228	PhosphoSitePlus;EPSD	COSMIC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	Q15910	EZH2	P49841	GSK3B	S363	R357L	357	Missense	distal	-6	no	8.182	8.238	PhosphoSitePlus;EPSD	COSMIC	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	Q15910	EZH2	P49841	GSK3B	S363	S363C	363	Missense	central	0	yes	8.182	0.000	PhosphoSitePlus;EPSD	COSMIC	6.007	Loss
CMGC_GSK_GSK3B_ST	Q15910	EZH2	P49841	GSK3B	S363	N361T	361	Missense	proximal	-2	no	8.182	8.438	PhosphoSitePlus;EPSD	COSMIC	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	Q15910	EZH2	P49841	GSK3B	S363	S366L	366	Missense	distal	3	no	8.182	7.882	PhosphoSitePlus;EPSD	COSMIC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	Q15910	EZH2	P49841	GSK3B	S408	R413W	413	Missense	distal	5	no	7.907	6.605	EPSD	COSMIC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	Q15910	EZH2	P49841	GSK3B	S408	S405L	405	Missense	distal	-3	no	7.907	7.917	EPSD	COSMIC	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	Q15910	EZH2	P49841	GSK3B	S408	E409K	409	Missense	proximal	1	no	7.907	8.195	EPSD	COSMIC	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	Q15910	EZH2	P49841	GSK3B	S408	S408F	408	Missense	central	0	yes	7.907	0.000	EPSD	COSMIC	6.007	Loss
CMGC_GSK_GSK3B_ST	Q15910	EZH2	P49841	GSK3B	S408	S412F	412	Missense	distal	4	no	7.907	4.293	EPSD	COSMIC	6.007	Loss
CMGC_GSK_GSK3B_ST	Q15910	EZH2	P49841	GSK3B	S408	Q415E	415	Missense	distal	7	no	7.907	7.856	EPSD	COSMIC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	Q15910	EZH2	P49841	GSK3B	S408	R413Q	413	Missense	distal	5	no	7.907	7.568	EPSD	COSMIC;CCLE	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	Q15910	EZH2	P49841	GSK3B	S475	P479S	479	Missense	distal	4	no	3.315	6.287	EPSD	COSMIC	6.007	Gain
CMGC_GSK_GSK3B_ST	Q15910	EZH2	P49841	GSK3B	T487	A482T	482	Missense	distal	-5	no	7.488	7.499	EPSD	COSMIC	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	Q15910	EZH2	P49841	GSK3B	T487	P488S	488	Missense	proximal	1	no	7.488	3.643	EPSD	COSMIC	6.007	Loss
CMGC_GSK_GSK3B_ST	Q15910	EZH2	P49841	GSK3B	T487	R494S	494	Missense	distal	7	no	7.488	7.050	EPSD	COSMIC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	Q15910	EZH2	P49841	GSK3B	T487	R494K	494	Missense	distal	7	no	7.488	6.981	EPSD	COSMIC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	Q15910	EZH2	P49841	GSK3B	T487	P481S	481	Missense	distal	-6	no	7.488	7.467	EPSD	COSMIC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	Q15910	EZH2	P49841	GSK3B	T487	P488A	488	Missense	proximal	1	no	7.488	3.755	EPSD	COSMIC	6.007	Loss
CMGC_GSK_GSK3B_ST	Q15910	EZH2	P49841	GSK3B	T487	K491R	491	Missense	distal	4	no	7.488	7.652	EPSD	COSMIC	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	Q9Y6H5	SNCAIP	P49841	GSK3B	S80	P86L	86	Missense	distal	6	no	6.090	6.084	EPSD	COSMIC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	Q9Y6H5	SNCAIP	P49841	GSK3B	S80	P75T	75	Missense	distal	-5	no	6.090	6.536	EPSD	COSMIC	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	Q9Y6H5	SNCAIP	P49841	GSK3B	S80	P75Q	75	Missense	distal	-5	no	6.090	6.390	EPSD	COSMIC	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	Q9Y6H5	SNCAIP	P49841	GSK3B	S80	Q85H	85	Missense	distal	5	no	6.090	5.440	EPSD	COSMIC	6.007	Loss
CMGC_GSK_GSK3B_ST	Q9Y6H5	SNCAIP	P49841	GSK3B	S80	R78L	78	Missense	proximal	-2	no	6.090	6.132	EPSD	COSMIC	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	Q9Y6H5	SNCAIP	P49841	GSK3B	S211	S215I	215	Missense	distal	4	no	9.226	5.904	EPSD	COSMIC	6.007	Loss
CMGC_GSK_GSK3B_ST	Q9Y6H5	SNCAIP	P49841	GSK3B	S211	V213M	213	Missense	proximal	2	no	9.226	8.924	EPSD	COSMIC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	Q9Y6H5	SNCAIP	P49841	GSK3B	S211	S211F	211	Missense	central	0	yes	9.226	0.000	EPSD	COSMIC	6.007	Loss
CMGC_GSK_GSK3B_ST	Q9Y6H5	SNCAIP	P49841	GSK3B	S215	R219T	219	Missense	distal	4	no	5.653	7.822	EPSD	COSMIC	6.007	Gain
CMGC_GSK_GSK3B_ST	Q9Y6H5	SNCAIP	P49841	GSK3B	S239	G246C	246	Missense	distal	7	no	7.654	8.026	EPSD	COSMIC	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	Q9Y6H5	SNCAIP	P49841	GSK3B	S239	K244R	244	Missense	distal	5	no	7.654	8.529	EPSD	COSMIC	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	Q9Y6H5	SNCAIP	P49841	GSK3B	T387	E384K	384	Missense	distal	-3	no	7.225	7.235	EPSD	COSMIC	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	Q9Y6H5	SNCAIP	P49841	GSK3B	T387	P388L	388	Missense	proximal	1	no	7.225	4.364	EPSD	COSMIC	6.007	Loss
CMGC_GSK_GSK3B_ST	Q9Y6H5	SNCAIP	P49841	GSK3B	T387	A389E	389	Missense	proximal	2	no	7.225	7.130	EPSD	COSMIC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	Q9Y6H5	SNCAIP	P49841	GSK3B	T387	R381H	381	Missense	distal	-6	no	7.225	7.248	EPSD	COSMIC	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	Q9Y6H5	SNCAIP	P49841	GSK3B	T387	E380K	380	Missense	distal	-7	no	7.225	7.214	EPSD	COSMIC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	Q9Y6H5	SNCAIP	P49841	GSK3B	T387	K394T	394	Missense	distal	7	no	7.225	7.235	EPSD	COSMIC	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	Q9Y6H5	SNCAIP	P49841	GSK3B	S552	K555N	555	Missense	distal	3	no	6.281	6.455	EPSD	COSMIC	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	Q9Y6H5	SNCAIP	P49841	GSK3B	S552	E548K	548	Missense	distal	-4	no	6.281	6.013	EPSD	COSMIC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	Q9Y6H5	SNCAIP	P49841	GSK3B	S552	S556R	556	Missense	distal	4	no	6.281	3.243	EPSD	COSMIC	6.007	Loss
CMGC_GSK_GSK3B_ST	Q9Y6H5	SNCAIP	P49841	GSK3B	S556	K555N	555	Missense	proximal	-1	no	10.517	10.524	PhosphoSitePlus	COSMIC	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	Q9Y6H5	SNCAIP	P49841	GSK3B	S556	S560P	560	Missense	distal	4	no	10.517	7.546	PhosphoSitePlus	COSMIC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	Q9Y6H5	SNCAIP	P49841	GSK3B	S556	P561S	561	Missense	distal	5	no	10.517	9.563	PhosphoSitePlus	COSMIC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	Q9Y6H5	SNCAIP	P49841	GSK3B	S556	S556R	556	Missense	central	0	yes	10.517	0.000	PhosphoSitePlus	COSMIC	6.007	Loss
CMGC_GSK_GSK3B_ST	Q9Y6H5	SNCAIP	P49841	GSK3B	S559	K555N	555	Missense	distal	-4	no	8.228	7.795	EPSD	COSMIC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	Q9Y6H5	SNCAIP	P49841	GSK3B	S559	S560P	560	Missense	proximal	1	no	8.228	12.073	EPSD	COSMIC	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	Q9Y6H5	SNCAIP	P49841	GSK3B	S559	P561S	561	Missense	proximal	2	no	8.228	7.784	EPSD	COSMIC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	Q9Y6H5	SNCAIP	P49841	GSK3B	S559	S556R	556	Missense	distal	-3	no	8.228	8.397	EPSD	COSMIC	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	Q9Y6H5	SNCAIP	P49841	GSK3B	S560	K555N	555	Missense	distal	-5	no	8.622	8.130	EPSD	COSMIC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	Q9Y6H5	SNCAIP	P49841	GSK3B	S560	S560P	560	Missense	central	0	yes	8.622	0.000	EPSD	COSMIC	6.007	Loss
CMGC_GSK_GSK3B_ST	Q9Y6H5	SNCAIP	P49841	GSK3B	S560	P561S	561	Missense	proximal	1	no	8.622	4.777	EPSD	COSMIC	6.007	Loss
CMGC_GSK_GSK3B_ST	Q9Y6H5	SNCAIP	P49841	GSK3B	S560	S556R	556	Missense	distal	-4	no	8.622	7.436	EPSD	COSMIC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	Q9Y6H5	SNCAIP	P49841	GSK3B	S562	K555N	555	Missense	distal	-7	no	7.051	7.036	EPSD	COSMIC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	Q9Y6H5	SNCAIP	P49841	GSK3B	S562	S560P	560	Missense	proximal	-2	no	7.051	7.308	EPSD	COSMIC	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	Q9Y6H5	SNCAIP	P49841	GSK3B	S562	P561S	561	Missense	proximal	-1	no	7.051	6.995	EPSD	COSMIC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	Q9Y6H5	SNCAIP	P49841	GSK3B	S562	S556R	556	Missense	distal	-6	no	7.051	6.994	EPSD	COSMIC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	Q9Y6H5	SNCAIP	P49841	GSK3B	S563	S560P	560	Missense	distal	-3	no	7.617	7.500	EPSD	COSMIC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	Q9Y6H5	SNCAIP	P49841	GSK3B	S563	P561S	561	Missense	proximal	-2	no	7.617	7.360	EPSD	COSMIC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	Q9Y6H5	SNCAIP	P49841	GSK3B	S563	S556R	556	Missense	distal	-7	no	7.617	7.635	EPSD	COSMIC	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	Q9Y6H5	SNCAIP	P49841	GSK3B	S565	S560P	560	Missense	distal	-5	no	7.092	6.936	EPSD	COSMIC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	Q9Y6H5	SNCAIP	P49841	GSK3B	S565	P561S	561	Missense	distal	-4	no	7.092	7.656	EPSD	COSMIC	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	Q9Y6H5	SNCAIP	P49841	GSK3B	S566	S560P	560	Missense	distal	-6	no	6.273	6.294	EPSD	COSMIC	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	Q9Y6H5	SNCAIP	P49841	GSK3B	S566	P561S	561	Missense	distal	-5	no	6.273	6.429	EPSD	COSMIC	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	Q9Y6H5	SNCAIP	P49841	GSK3B	S566	Q573H	573	Missense	distal	7	no	6.273	6.809	EPSD	COSMIC	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	Q9Y6H5	SNCAIP	P49841	GSK3B	S674	R668C	668	Missense	distal	-6	no	6.055	6.101	EPSD	COSMIC	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	Q9Y6H5	SNCAIP	P49841	GSK3B	S674	E677K	677	Missense	distal	3	no	6.055	5.948	EPSD	COSMIC	6.007	Loss
CMGC_GSK_GSK3B_ST	Q9Y6H5	SNCAIP	P49841	GSK3B	S674	L675P	675	Missense	proximal	1	no	6.055	8.916	EPSD	COSMIC	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	Q9Y6H5	SNCAIP	P49841	GSK3B	S674	D681N	681	Missense	distal	7	no	6.055	6.124	EPSD	COSMIC	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	Q9Y6H5	SNCAIP	P49841	GSK3B	S674	R673M	673	Missense	proximal	-1	no	6.055	6.142	EPSD	COSMIC	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	Q9Y6H5	SNCAIP	P49841	GSK3B	S676	E677K	677	Missense	proximal	1	no	6.253	6.540	EPSD	COSMIC	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	Q9Y6H5	SNCAIP	P49841	GSK3B	S676	L675P	675	Missense	proximal	-1	no	6.253	6.384	EPSD	COSMIC	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	Q9Y6H5	SNCAIP	P49841	GSK3B	S676	D681N	681	Missense	distal	5	no	6.253	5.826	EPSD	COSMIC	6.007	Loss
CMGC_GSK_GSK3B_ST	Q9Y6H5	SNCAIP	P49841	GSK3B	S676	R673M	673	Missense	distal	-3	no	6.253	6.056	EPSD	COSMIC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	Q9Y6H5	SNCAIP	P49841	GSK3B	S678	E677K	677	Missense	proximal	-1	no	8.105	8.171	EPSD	COSMIC	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	Q9Y6H5	SNCAIP	P49841	GSK3B	S678	S685C	685	Missense	distal	7	no	8.105	8.497	EPSD	COSMIC	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	Q9Y6H5	SNCAIP	P49841	GSK3B	S678	L675P	675	Missense	distal	-3	no	8.105	7.978	EPSD	COSMIC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	Q9Y6H5	SNCAIP	P49841	GSK3B	S678	D681N	681	Missense	distal	3	no	8.105	8.058	EPSD	COSMIC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	Q9Y6H5	SNCAIP	P49841	GSK3B	S678	R673M	673	Missense	distal	-5	no	8.105	7.709	EPSD	COSMIC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	Q9Y6H5	SNCAIP	P49841	GSK3B	S747	E753D	753	Missense	distal	6	no	8.771	8.769	EPSD	COSMIC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	Q9Y6H5	SNCAIP	P49841	GSK3B	S747	P748L	748	Missense	proximal	1	no	8.771	5.910	EPSD	COSMIC	6.007	Loss
CMGC_GSK_GSK3B_ST	Q9Y6H5	SNCAIP	P49841	GSK3B	S747	P748S	748	Missense	proximal	1	no	8.771	4.926	EPSD	COSMIC	6.007	Loss
CMGC_GSK_GSK3B_ST	Q9Y6H5	SNCAIP	P49841	GSK3B	S747	H746Q	746	Missense	proximal	-1	no	8.771	8.716	EPSD	COSMIC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	Q9Y6H5	SNCAIP	P49841	GSK3B	S755	E756Q	756	Missense	proximal	1	no	5.854	6.419	EPSD	COSMIC	6.007	Gain
CMGC_GSK_GSK3B_ST	Q02156	PRKCE	P49841	GSK3B	T228	V232G	232	Missense	distal	4	no	6.783	5.929	EPSD	COSMIC	6.007	Loss
CMGC_GSK_GSK3B_ST	Q02156	PRKCE	P49841	GSK3B	T228	Q231H	231	Missense	distal	3	no	6.783	6.792	EPSD	COSMIC	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	Q02156	PRKCE	P49841	GSK3B	T228	K224N	224	Missense	distal	-4	no	6.783	6.350	EPSD	COSMIC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	Q02156	PRKCE	P49841	GSK3B	T228	G233C	233	Missense	distal	5	no	6.783	5.500	EPSD	COSMIC	6.007	Loss
CMGC_GSK_GSK3B_ST	Q02156	PRKCE	P49841	GSK3B	S234	V232G	232	Missense	proximal	-2	no	7.285	7.200	EPSD	COSMIC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	Q02156	PRKCE	P49841	GSK3B	S234	Q231H	231	Missense	distal	-3	no	7.285	7.367	EPSD	COSMIC	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	Q02156	PRKCE	P49841	GSK3B	S234	R236Q	236	Missense	proximal	2	no	7.285	7.489	EPSD	COSMIC	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	Q02156	PRKCE	P49841	GSK3B	S234	G233C	233	Missense	proximal	-1	no	7.285	7.242	EPSD	COSMIC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	Q02156	PRKCE	P49841	GSK3B	T309	N315D	315	Missense	distal	6	no	6.743	6.742	EPSD	COSMIC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	Q02156	PRKCE	P49841	GSK3B	S329	P330S	330	Missense	proximal	1	no	7.855	4.011	EPSD	COSMIC	6.007	Loss
CMGC_GSK_GSK3B_ST	Q02156	PRKCE	P49841	GSK3B	S337	P330S	330	Missense	distal	-7	no	6.387	6.388	EPSD	COSMIC	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	Q02156	PRKCE	P49841	GSK3B	S388	P389T	389	Missense	proximal	1	no	7.823	4.632	EPSD	COSMIC	6.007	Loss
CMGC_GSK_GSK3B_ST	P10914	IRF1	P49841	GSK3B	S184	P185L	185	Missense	proximal	1	no	6.540	3.679	PhosphoSitePlus	COSMIC	6.007	Loss
CMGC_GSK_GSK3B_ST	P10914	IRF1	P49841	GSK3B	S184	S190C	190	Missense	distal	6	no	6.540	6.527	PhosphoSitePlus	COSMIC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	P10914	IRF1	P49841	GSK3B	S215	E222A	222	Missense	distal	7	no	9.080	9.389	EPSD	COSMIC	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	P10914	IRF1	P49841	GSK3B	S215	S219F	219	Missense	distal	4	no	9.080	5.466	EPSD	COSMIC	6.007	Loss
CMGC_GSK_GSK3B_ST	P10914	IRF1	P49841	GSK3B	S215	Y210F	210	Missense	distal	-5	no	9.080	8.988	EPSD	COSMIC;GDSC;CCLE	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	P10914	IRF1	P49841	GSK3B	T311	R314W	314	Missense	distal	3	no	6.650	6.909	EPSD	COSMIC	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	P10914	IRF1	P49841	GSK3B	T311	T311I	311	Missense	central	0	yes	6.650	0.000	EPSD	COSMIC	6.007	Loss
CMGC_GSK_GSK3B_ST	Q9BYG3	NIFK	P49841	GSK3B	T220	P224S	224	Missense	distal	4	no	3.382	6.354	EPSD	COSMIC	6.007	Gain
CMGC_GSK_GSK3B_ST	Q9BYG3	NIFK	P49841	GSK3B	T223	K226N	226	Missense	distal	3	no	8.408	8.583	EPSD	COSMIC	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	Q9BYG3	NIFK	P49841	GSK3B	T223	P224S	224	Missense	proximal	1	no	8.408	4.564	EPSD	COSMIC	6.007	Loss
CMGC_GSK_GSK3B_ST	Q9BYG3	NIFK	P49841	GSK3B	S230	P235S	235	Missense	distal	5	no	8.011	7.057	PhosphoSitePlus;EPSD	COSMIC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	Q9BYG3	NIFK	P49841	GSK3B	S230	K226N	226	Missense	distal	-4	no	8.011	7.578	PhosphoSitePlus;EPSD	COSMIC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	Q9BYG3	NIFK	P49841	GSK3B	S230	P224S	224	Missense	distal	-6	no	8.011	7.990	PhosphoSitePlus;EPSD	COSMIC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	Q9BYG3	NIFK	P49841	GSK3B	T234	P235S	235	Missense	proximal	1	no	10.460	6.616	EPSD;PhosphoSitePlus	COSMIC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	Q9BYG3	NIFK	P49841	GSK3B	T238	R245Q	245	Missense	distal	7	no	7.813	7.466	EPSD	COSMIC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	Q9BYG3	NIFK	P49841	GSK3B	T238	E243K	243	Missense	distal	5	no	7.813	6.946	EPSD	COSMIC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	Q9BYG3	NIFK	P49841	GSK3B	T238	P235S	235	Missense	distal	-3	no	7.813	7.930	EPSD	COSMIC	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	Q9BYG3	NIFK	P49841	GSK3B	T238	E243D	243	Missense	distal	5	no	7.813	7.611	EPSD	COSMIC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	Q9BYG3	NIFK	P49841	GSK3B	T277	H282R	282	Missense	distal	5	no	6.180	7.169	EPSD	COSMIC	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	Q9BYG3	NIFK	P49841	GSK3B	T277	E272Q	272	Missense	distal	-5	no	6.180	5.892	EPSD	COSMIC	6.007	Loss
CMGC_GSK_GSK3B_ST	Q9BYG3	NIFK	P49841	GSK3B	T279	H282R	282	Missense	distal	3	no	10.617	10.275	EPSD	COSMIC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	Q9BYG3	NIFK	P49841	GSK3B	T279	E272Q	272	Missense	distal	-7	no	10.617	10.600	EPSD	COSMIC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	P16220	CREB1	P49841	GSK3B	T104	S103N	103	Missense	proximal	-1	no	6.437	6.499	EPSD	COSMIC	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	P16220	CREB1	P49841	GSK3B	T104	E109K	109	Missense	distal	5	no	6.437	5.570	EPSD	COSMIC	6.007	Loss
CMGC_GSK_GSK3B_ST	P16220	CREB1	P49841	GSK3B	T104	I102M	102	Missense	proximal	-2	no	6.437	6.117	EPSD	COSMIC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	P16220	CREB1	P49841	GSK3B	S117	S117N	117	Missense	central	0	yes	8.249	0.000	EPSD	COSMIC	6.007	Loss
CMGC_GSK_GSK3B_ST	P16220	CREB1	P49841	GSK3B	S117	R124Q	124	Missense	distal	7	no	8.249	7.901	EPSD	COSMIC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	P16220	CREB1	P49841	GSK3B	S117	V118L	118	Missense	proximal	1	no	8.249	8.379	EPSD	COSMIC	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	P16220	CREB1	P49841	GSK3B	S117	V118I	118	Missense	proximal	1	no	8.249	7.358	EPSD	COSMIC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	P16220	CREB1	P49841	GSK3B	S121	R125T	125	Missense	distal	4	no	4.525	6.694	EPSD	COSMIC	6.007	Gain
CMGC_GSK_GSK3B_ST	P16220	CREB1	P49841	GSK3B	S129	R124Q	124	Missense	distal	-5	no	7.644	7.090	PhosphoSitePlus	COSMIC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	P16220	CREB1	P49841	GSK3B	S129	R125T	125	Missense	distal	-4	no	7.644	8.495	PhosphoSitePlus	COSMIC	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	P16220	CREB1	P49841	GSK3B	S129	L128R	128	Missense	proximal	-1	no	7.644	7.582	PhosphoSitePlus	COSMIC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	P16220	CREB1	P49841	GSK3B	T256	A257T	257	Missense	proximal	1	no	5.626	6.167	EPSD	COSMIC	6.007	Gain
CMGC_GSK_GSK3B_ST	P16220	CREB1	P49841	GSK3B	S260	P264T	264	Missense	distal	4	no	5.891	7.993	EPSD	COSMIC;GDSC;CCLE	6.007	Gain
CMGC_GSK_GSK3B_ST	P16220	CREB1	P49841	GSK3B	S271	A269T	269	Missense	proximal	-2	no	5.802	6.164	EPSD	COSMIC	6.007	Gain
CMGC_GSK_GSK3B_ST	P40337	VHL	P49841	GSK3B	S38	E42V	42	Missense	distal	4	no	6.340	5.971	EPSD	COSMIC	6.007	Loss
CMGC_GSK_GSK3B_ST	P40337	VHL	P49841	GSK3B	S38	S38F	38	Missense	central	0	yes	6.340	0.000	EPSD	COSMIC	6.007	Loss
CMGC_GSK_GSK3B_ST	P40337	VHL	P49841	GSK3B	S38	G39D	39	Missense	proximal	1	no	6.340	6.431	EPSD	COSMIC	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	P40337	VHL	P49841	GSK3B	S38	P40L	40	Missense	proximal	2	no	6.340	5.956	EPSD	COSMIC	6.007	Loss
CMGC_GSK_GSK3B_ST	P40337	VHL	P49841	GSK3B	S38	P45R	45	Missense	distal	7	no	6.340	6.841	EPSD	COSMIC;CCLE	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	P40337	VHL	P49841	GSK3B	S38	G39S	39	Missense	proximal	1	no	6.340	5.690	EPSD	COSMIC	6.007	Loss
CMGC_GSK_GSK3B_ST	P40337	VHL	P49841	GSK3B	S38	S33A	33	Missense	distal	-5	no	6.340	6.618	EPSD	COSMIC	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	P40337	VHL	P49841	GSK3B	S38	P45L	45	Missense	distal	7	no	6.340	6.389	EPSD	COSMIC	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	P40337	VHL	P49841	GSK3B	S38	S43F	43	Missense	distal	5	no	6.340	5.673	EPSD	COSMIC	6.007	Loss
CMGC_GSK_GSK3B_ST	P40337	VHL	P49841	GSK3B	S38	P40S	40	Missense	proximal	2	no	6.340	5.896	EPSD	COSMIC	6.007	Loss
CMGC_GSK_GSK3B_ST	P40337	VHL	P49841	GSK3B	S38	E41V	41	Missense	distal	3	no	6.340	6.152	EPSD	COSMIC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	P40337	VHL	P49841	GSK3B	S38	G44D	44	Missense	distal	6	no	6.340	6.336	EPSD	COSMIC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	P40337	VHL	P49841	GSK3B	S38	E41G	41	Missense	distal	3	no	6.340	6.403	EPSD	COSMIC	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	P40337	VHL	P49841	GSK3B	S38	A35S	35	Missense	distal	-3	no	6.340	6.320	EPSD	COSMIC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	P40337	VHL	P49841	GSK3B	S38	E37K	37	Missense	proximal	-1	no	6.340	6.407	EPSD	COSMIC	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	P40337	VHL	P49841	GSK3B	S38	G34C	34	Missense	distal	-4	no	6.340	4.654	EPSD	COSMIC	6.007	Loss
CMGC_GSK_GSK3B_ST	P40337	VHL	P49841	GSK3B	S38	E42K	42	Missense	distal	4	no	6.340	5.158	EPSD	COSMIC	6.007	Loss
CMGC_GSK_GSK3B_ST	P40337	VHL	P49841	GSK3B	S38	P45S	45	Missense	distal	7	no	6.340	6.404	EPSD	COSMIC	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	P40337	VHL	P49841	GSK3B	S38	E31G	31	Missense	distal	-7	no	6.340	6.306	EPSD	COSMIC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	P40337	VHL	P49841	GSK3B	S68	S65T	65	Missense	distal	-3	no	7.731	7.755	PhosphoSitePlus	COSMIC	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	P40337	VHL	P49841	GSK3B	S68	Q73H	73	Missense	distal	5	no	7.731	7.080	PhosphoSitePlus	COSMIC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	P40337	VHL	P49841	GSK3B	S68	P71T	71	Missense	distal	3	no	7.731	7.680	PhosphoSitePlus	COSMIC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	P40337	VHL	P49841	GSK3B	S68	S65Q	65	Missense	distal	-3	no	7.731	7.760	PhosphoSitePlus	COSMIC	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	P40337	VHL	P49841	GSK3B	S68	S65A	65	Missense	distal	-3	no	7.731	7.751	PhosphoSitePlus	COSMIC	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	P40337	VHL	P49841	GSK3B	S68	R64P	64	Missense	distal	-4	no	7.731	8.354	PhosphoSitePlus	COSMIC	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	P40337	VHL	P49841	GSK3B	S68	S72P	72	Missense	distal	4	no	7.731	4.759	PhosphoSitePlus	COSMIC	6.007	Loss
CMGC_GSK_GSK3B_ST	P40337	VHL	P49841	GSK3B	S68	S68P	68	Missense	central	0	yes	7.731	0.000	PhosphoSitePlus	COSMIC	6.007	Loss
CMGC_GSK_GSK3B_ST	P40337	VHL	P49841	GSK3B	S68	Q73K	73	Missense	distal	5	no	7.731	7.195	PhosphoSitePlus	COSMIC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	P40337	VHL	P49841	GSK3B	S68	N67S	67	Missense	proximal	-1	no	7.731	7.669	PhosphoSitePlus	COSMIC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	P40337	VHL	P49841	GSK3B	S68	I75V	75	Missense	distal	7	no	7.731	7.820	PhosphoSitePlus	COSMIC	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	P40337	VHL	P49841	GSK3B	S68	R64S	64	Missense	distal	-4	no	7.731	8.917	PhosphoSitePlus	COSMIC	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	P40337	VHL	P49841	GSK3B	S68	S68L	68	Missense	central	0	yes	7.731	0.000	PhosphoSitePlus	COSMIC	6.007	Loss
CMGC_GSK_GSK3B_ST	P40337	VHL	P49841	GSK3B	S68	R69C	69	Missense	proximal	1	no	7.731	5.728	PhosphoSitePlus	COSMIC	6.007	Loss
CMGC_GSK_GSK3B_ST	P40337	VHL	P49841	GSK3B	S72	F76S	76	Missense	distal	4	no	2.484	6.099	EPSD	COSMIC	6.007	Gain
CMGC_GSK_GSK3B_ST	P40337	VHL	P49841	GSK3B	S80	N78T	78	Missense	proximal	-2	no	6.622	6.878	EPSD	COSMIC;CCLE	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	P40337	VHL	P49841	GSK3B	S80	F76Y	76	Missense	distal	-4	no	6.622	6.976	EPSD	COSMIC	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	P40337	VHL	P49841	GSK3B	S80	P81S	81	Missense	proximal	1	no	6.622	2.777	EPSD	COSMIC	6.007	Loss
CMGC_GSK_GSK3B_ST	P40337	VHL	P49841	GSK3B	S80	Q73H	73	Missense	distal	-7	no	6.622	6.625	EPSD	COSMIC	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	P40337	VHL	P49841	GSK3B	S80	P86R	86	Missense	distal	6	no	6.622	6.616	EPSD	COSMIC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	P40337	VHL	P49841	GSK3B	S80	F76S	76	Missense	distal	-4	no	6.622	7.776	EPSD	COSMIC	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	P40337	VHL	P49841	GSK3B	S80	R82G	82	Missense	proximal	2	no	6.622	6.345	EPSD	COSMIC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	P40337	VHL	P49841	GSK3B	S80	V87I	87	Missense	distal	7	no	6.622	6.532	EPSD	COSMIC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	P40337	VHL	P49841	GSK3B	S80	F76L	76	Missense	distal	-4	no	6.622	6.426	EPSD	COSMIC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	P40337	VHL	P49841	GSK3B	S80	V83I	83	Missense	distal	3	no	6.622	6.410	EPSD	COSMIC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	P40337	VHL	P49841	GSK3B	S80	P86H	86	Missense	distal	6	no	6.622	6.610	EPSD	COSMIC;CCLE	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	P40337	VHL	P49841	GSK3B	S80	P81L	81	Missense	proximal	1	no	6.622	3.761	EPSD	COSMIC	6.007	Loss
CMGC_GSK_GSK3B_ST	P40337	VHL	P49841	GSK3B	S80	V84L	84	Missense	distal	4	no	6.622	6.294	EPSD	COSMIC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	P40337	VHL	P49841	GSK3B	S80	R82L	82	Missense	proximal	2	no	6.622	6.663	EPSD	COSMIC	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	P40337	VHL	P49841	GSK3B	S80	C77S	77	Missense	distal	-3	no	6.622	6.518	EPSD	COSMIC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	P40337	VHL	P49841	GSK3B	S80	S80F	80	Missense	central	0	yes	6.622	0.000	EPSD	COSMIC	6.007	Loss
CMGC_GSK_GSK3B_ST	P40337	VHL	P49841	GSK3B	S80	Q73K	73	Missense	distal	-7	no	6.622	6.628	EPSD	COSMIC	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	P40337	VHL	P49841	GSK3B	S80	R82C	82	Missense	proximal	2	no	6.622	6.111	EPSD	COSMIC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	P40337	VHL	P49841	GSK3B	S80	V84E	84	Missense	distal	4	no	6.622	6.991	EPSD	COSMIC	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	P40337	VHL	P49841	GSK3B	S80	P81Q	81	Missense	proximal	1	no	6.622	3.354	EPSD	COSMIC	6.007	Loss
CMGC_GSK_GSK3B_ST	P40337	VHL	P49841	GSK3B	S80	V87A	87	Missense	distal	7	no	6.622	6.544	EPSD	COSMIC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	P40337	VHL	P49841	GSK3B	S80	I75V	75	Missense	distal	-5	no	6.622	6.729	EPSD	COSMIC	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	P40337	VHL	P49841	GSK3B	S80	N78H	78	Missense	proximal	-2	no	6.622	6.745	EPSD	COSMIC	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	P40337	VHL	P49841	GSK3B	S80	P86A	86	Missense	distal	6	no	6.622	6.618	EPSD	COSMIC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	P40337	VHL	P49841	GSK3B	S80	P81T	81	Missense	proximal	1	no	6.622	3.431	EPSD	COSMIC	6.007	Loss
CMGC_GSK_GSK3B_ST	P40337	VHL	P49841	GSK3B	S80	V84M	84	Missense	distal	4	no	6.622	6.777	EPSD	COSMIC	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	P40337	VHL	P49841	GSK3B	S80	S80I	80	Missense	central	0	yes	6.622	0.000	EPSD	COSMIC	6.007	Loss
CMGC_GSK_GSK3B_ST	P40337	VHL	P49841	GSK3B	S80	S80G	80	Missense	central	0	yes	6.622	0.000	EPSD	COSMIC	6.007	Loss
CMGC_GSK_GSK3B_ST	P40337	VHL	P49841	GSK3B	S168	P172T	172	Missense	distal	4	no	4.503	6.605	EPSD	COSMIC	6.007	Gain
CMGC_GSK_GSK3B_ST	P40337	VHL	P49841	GSK3B	S168	P172S	172	Missense	distal	4	no	4.503	7.474	EPSD	COSMIC	6.007	Gain
CMGC_GSK_GSK3B_ST	Q9H0Z9	RBM38	P49841	GSK3B	S195	A193T	193	Missense	proximal	-2	no	7.188	7.550	PhosphoSitePlus	COSMIC	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	Q9H0Z9	RBM38	P49841	GSK3B	S195	T198S	198	Missense	distal	3	no	7.188	7.220	PhosphoSitePlus	COSMIC	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	Q9H0Z9	RBM38	P49841	GSK3B	S195	Q189K	189	Missense	distal	-6	no	7.188	7.129	PhosphoSitePlus	COSMIC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	Q01201	RELB	P49841	GSK3B	S44	S50R	50	Missense	distal	6	no	9.270	9.266	EPSD	COSMIC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	Q01201	RELB	P49841	GSK3B	S116	P123Q	123	Missense	distal	7	no	7.970	8.123	EPSD	COSMIC	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	Q01201	RELB	P49841	GSK3B	S116	C109S	109	Missense	distal	-7	no	7.970	7.947	EPSD	COSMIC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	Q01201	RELB	P49841	GSK3B	S116	P121Q	121	Missense	distal	5	no	7.970	6.993	EPSD	COSMIC;CCLE	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	Q01201	RELB	P49841	GSK3B	S217	H215R	215	Missense	proximal	-2	no	8.605	8.594	EPSD	COSMIC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	Q01201	RELB	P49841	GSK3B	S217	S221I	221	Missense	distal	4	no	8.605	5.283	EPSD	COSMIC	6.007	Loss
CMGC_GSK_GSK3B_ST	Q01201	RELB	P49841	GSK3B	S217	P214S	214	Missense	distal	-3	no	8.605	8.721	EPSD	COSMIC	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	Q01201	RELB	P49841	GSK3B	S217	H220Y	220	Missense	distal	3	no	8.605	8.211	EPSD	COSMIC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	Q01201	RELB	P49841	GSK3B	S217	R211L	211	Missense	distal	-6	no	8.605	8.661	EPSD	COSMIC	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	Q01201	RELB	P49841	GSK3B	S217	R219W	219	Missense	proximal	2	no	8.605	8.175	EPSD	COSMIC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	Q01201	RELB	P49841	GSK3B	S573	L571I	571	Missense	proximal	-2	no	9.095	9.158	PhosphoSitePlus	COSMIC	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	Q04206	RELA	P49841	GSK3B	T71	N64S	64	Missense	distal	-7	no	6.110	6.104	EPSD	COSMIC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	Q04206	RELA	P49841	GSK3B	T254	I250V	250	Missense	distal	-4	no	5.659	6.908	EPSD	COSMIC	6.007	Gain
CMGC_GSK_GSK3B_ST	Q04206	RELA	P49841	GSK3B	T322	P326S	326	Missense	distal	4	no	3.431	6.402	EPSD	COSMIC	6.007	Gain
CMGC_GSK_GSK3B_ST	Q04206	RELA	P49841	GSK3B	T505	E498V	498	Missense	distal	-7	no	6.176	6.165	EPSD	COSMIC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	Q04206	RELA	P49841	GSK3B	T505	R502P	502	Missense	distal	-3	no	6.176	5.890	EPSD	COSMIC	6.007	Loss
CMGC_GSK_GSK3B_ST	Q04206	RELA	P49841	GSK3B	T505	T501I	501	Missense	distal	-4	no	6.176	4.029	EPSD	COSMIC	6.007	Loss
CMGC_GSK_GSK3B_ST	Q04206	RELA	P49841	GSK3B	T505	A499T	499	Missense	distal	-6	no	6.176	6.107	EPSD	COSMIC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	P30279	CCND2	P49841	GSK3B	T280	P281A	281	Missense	proximal	1	no	9.037	5.305	PhosphoSitePlus	COSMIC;GDSC;CCLE	6.007	Loss
CMGC_GSK_GSK3B_ST	P30279	CCND2	P49841	GSK3B	T280	D276E	276	Missense	distal	-4	no	9.037	9.040	PhosphoSitePlus	COSMIC	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	P30279	CCND2	P49841	GSK3B	T280	P281L	281	Missense	proximal	1	no	9.037	6.176	PhosphoSitePlus	COSMIC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	P30279	CCND2	P49841	GSK3B	T280	D283E	283	Missense	distal	3	no	9.037	8.923	PhosphoSitePlus	COSMIC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	P30279	CCND2	P49841	GSK3B	T280	V284M	284	Missense	distal	4	no	9.037	9.192	PhosphoSitePlus	COSMIC;GDSC;CCLE	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	P30279	CCND2	P49841	GSK3B	T280	P281N	281	Missense	proximal	1	no	9.037	3.517	PhosphoSitePlus	COSMIC	6.007	Loss
CMGC_GSK_GSK3B_ST	Q16555	DPYSL2	P49841	GSK3B	S288	K293N	293	Missense	distal	5	no	5.800	6.038	EPSD	COSMIC	6.007	Gain
CMGC_GSK_GSK3B_ST	Q16555	DPYSL2	P49841	GSK3B	S304	A298T	298	Missense	distal	-6	no	10.759	10.690	EPSD	COSMIC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	Q16555	DPYSL2	P49841	GSK3B	S304	P305L	305	Missense	proximal	1	no	10.759	7.898	EPSD	COSMIC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	Q16555	DPYSL2	P49841	GSK3B	S304	P305T	305	Missense	proximal	1	no	10.759	7.568	EPSD	COSMIC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	Q16555	DPYSL2	P49841	GSK3B	S304	V302F	302	Missense	proximal	-2	no	10.759	10.461	EPSD	COSMIC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	Q16555	DPYSL2	P49841	GSK3B	S304	L307S	307	Missense	distal	3	no	10.759	11.059	EPSD	COSMIC	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	Q16555	DPYSL2	P49841	GSK3B	S308	P305L	305	Missense	distal	-3	no	8.416	8.542	EPSD	COSMIC	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	Q16555	DPYSL2	P49841	GSK3B	S308	P305T	305	Missense	distal	-3	no	8.416	8.558	EPSD	COSMIC	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	Q16555	DPYSL2	P49841	GSK3B	S308	V302F	302	Missense	distal	-6	no	8.416	8.430	EPSD	COSMIC	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	Q16555	DPYSL2	P49841	GSK3B	S308	L307S	307	Missense	proximal	-1	no	8.416	8.491	EPSD	COSMIC	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	Q16555	DPYSL2	P49841	GSK3B	T509	V506A	506	Missense	distal	-3	no	8.948	8.801	PhosphoSitePlus;EPSD	COSMIC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	Q16555	DPYSL2	P49841	GSK3B	S542	I546T	546	Missense	distal	4	no	3.706	6.159	EPSD	COSMIC	6.007	Gain
CMGC_GSK_GSK3B_ST	P17676	CEBPB	P49841	GSK3B	S76	H69Q	69	Missense	distal	-7	no	9.406	9.403	EPSD	COSMIC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	Q08050	FOXM1	P49841	GSK3B	S35	E31K	31	Missense	distal	-4	no	6.762	6.495	EPSD	COSMIC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	Q08050	FOXM1	P49841	GSK3B	S451	E448K	448	Missense	distal	-3	no	7.123	7.133	EPSD	COSMIC	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	Q08050	FOXM1	P49841	GSK3B	S451	P455L	455	Missense	distal	4	no	7.123	7.376	EPSD	COSMIC	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	Q08050	FOXM1	P49841	GSK3B	S451	P455S	455	Missense	distal	4	no	7.123	10.094	EPSD	COSMIC	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	Q08050	FOXM1	P49841	GSK3B	S451	F450L	450	Missense	proximal	-1	no	7.123	7.178	EPSD	COSMIC	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	Q08050	FOXM1	P49841	GSK3B	S481	E486Q	486	Missense	distal	5	no	6.189	5.858	EPSD	COSMIC	6.007	Loss
CMGC_GSK_GSK3B_ST	Q08050	FOXM1	P49841	GSK3B	S481	E480K	480	Missense	proximal	-1	no	6.189	6.256	EPSD	COSMIC	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	Q08050	FOXM1	P49841	GSK3B	S489	E486Q	486	Missense	distal	-3	no	9.825	9.842	EPSD	COSMIC	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	Q08050	FOXM1	P49841	GSK3B	S489	P492L	492	Missense	distal	3	no	9.825	9.507	EPSD	COSMIC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	Q08050	FOXM1	P49841	GSK3B	S501	S505L	505	Missense	distal	4	no	8.197	5.479	EPSD	COSMIC	6.007	Loss
CMGC_GSK_GSK3B_ST	Q08050	FOXM1	P49841	GSK3B	S506	S505L	505	Missense	proximal	-1	no	6.083	6.008	EPSD	COSMIC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	Q08050	FOXM1	P49841	GSK3B	S506	T510N	510	Missense	distal	4	no	6.083	3.342	EPSD	COSMIC;CCLE	6.007	Loss
CMGC_GSK_GSK3B_ST	Q08050	FOXM1	P49841	GSK3B	S508	S505L	505	Missense	distal	-3	no	6.417	6.427	EPSD	COSMIC	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	Q08050	FOXM1	P49841	GSK3B	S508	T510N	510	Missense	proximal	2	no	6.417	5.759	EPSD	COSMIC;CCLE	6.007	Loss
CMGC_GSK_GSK3B_ST	Q08050	FOXM1	P49841	GSK3B	T510	S505L	505	Missense	distal	-5	no	7.126	7.235	EPSD	COSMIC	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	Q08050	FOXM1	P49841	GSK3B	T510	T510N	510	Missense	central	0	yes	7.126	0.000	EPSD	COSMIC;CCLE	6.007	Loss
CMGC_GSK_GSK3B_ST	Q08050	FOXM1	P49841	GSK3B	S518	R521M	521	Missense	distal	3	no	7.087	7.267	EPSD	COSMIC	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	Q08050	FOXM1	P49841	GSK3B	S518	T524S	524	Missense	distal	6	no	7.087	7.085	EPSD	COSMIC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	Q08050	FOXM1	P49841	GSK3B	S518	S518I	518	Missense	central	0	yes	7.087	0.000	EPSD	COSMIC	6.007	Loss
CMGC_GSK_GSK3B_ST	Q08050	FOXM1	P49841	GSK3B	S518	R525W	525	Missense	distal	7	no	7.087	7.195	EPSD	COSMIC	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	Q08050	FOXM1	P49841	GSK3B	S522	C526S	526	Missense	distal	4	no	3.443	9.576	EPSD	COSMIC	6.007	Gain
CMGC_GSK_GSK3B_ST	Q08050	FOXM1	P49841	GSK3B	T524	R521M	521	Missense	distal	-3	no	7.221	7.024	EPSD	COSMIC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	Q08050	FOXM1	P49841	GSK3B	T524	S518I	518	Missense	distal	-6	no	7.221	7.158	EPSD	COSMIC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	Q08050	FOXM1	P49841	GSK3B	T524	V527A	527	Missense	distal	3	no	7.221	7.092	EPSD	COSMIC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	Q08050	FOXM1	P49841	GSK3B	T524	R525W	525	Missense	proximal	1	no	7.221	7.439	EPSD	COSMIC	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	Q08050	FOXM1	P49841	GSK3B	T524	C526S	526	Missense	proximal	2	no	7.221	7.714	EPSD	COSMIC	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	Q08050	FOXM1	P49841	GSK3B	S582	A579S	579	Missense	distal	-3	no	7.070	7.049	EPSD	COSMIC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	Q08050	FOXM1	P49841	GSK3B	S582	S589N	589	Missense	distal	7	no	7.070	7.193	EPSD	COSMIC	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	Q08050	FOXM1	P49841	GSK3B	S582	S586T	586	Missense	distal	4	no	7.070	6.201	EPSD	COSMIC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	Q08050	FOXM1	P49841	GSK3B	S582	S581C	581	Missense	proximal	-1	no	7.070	7.034	EPSD	COSMIC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	Q08050	FOXM1	P49841	GSK3B	S582	P584S	584	Missense	proximal	2	no	7.070	6.626	EPSD	COSMIC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	Q08050	FOXM1	P49841	GSK3B	S582	F577I	577	Missense	distal	-5	no	7.070	6.983	EPSD	COSMIC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	Q08050	FOXM1	P49841	GSK3B	S582	S582F	582	Missense	central	0	yes	7.070	0.000	EPSD	COSMIC	6.007	Loss
CMGC_GSK_GSK3B_ST	Q08050	FOXM1	P49841	GSK3B	T600	T605M	605	Missense	distal	5	no	8.205	8.089	EPSD	COSMIC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	Q08050	FOXM1	P49841	GSK3B	T605	S610T	610	Missense	distal	5	no	7.401	7.379	EPSD	COSMIC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	Q08050	FOXM1	P49841	GSK3B	T605	T605M	605	Missense	central	0	yes	7.401	0.000	EPSD	COSMIC	6.007	Loss
CMGC_GSK_GSK3B_ST	Q08050	FOXM1	P49841	GSK3B	S609	S615Y	615	Missense	distal	6	no	6.673	6.667	EPSD	COSMIC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	Q08050	FOXM1	P49841	GSK3B	S609	S610T	610	Missense	proximal	1	no	6.673	7.326	EPSD	COSMIC	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	Q08050	FOXM1	P49841	GSK3B	S609	T605M	605	Missense	distal	-4	no	6.673	5.948	EPSD	COSMIC	6.007	Loss
CMGC_GSK_GSK3B_ST	Q08050	FOXM1	P49841	GSK3B	T611	S615Y	615	Missense	distal	4	no	8.201	4.688	EPSD	COSMIC	6.007	Loss
CMGC_GSK_GSK3B_ST	Q08050	FOXM1	P49841	GSK3B	T611	S610T	610	Missense	proximal	-1	no	8.201	8.126	EPSD	COSMIC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	Q08050	FOXM1	P49841	GSK3B	T611	T605M	605	Missense	distal	-6	no	8.201	8.206	EPSD	COSMIC	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	Q08050	FOXM1	P49841	GSK3B	S613	S615Y	615	Missense	proximal	2	no	6.371	6.139	EPSD	COSMIC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	Q08050	FOXM1	P49841	GSK3B	S613	S610T	610	Missense	distal	-3	no	6.371	6.396	EPSD	COSMIC	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	Q08050	FOXM1	P49841	GSK3B	T620	S615Y	615	Missense	distal	-5	no	5.406	6.058	EPSD	COSMIC	6.007	Gain
CMGC_GSK_GSK3B_ST	Q08050	FOXM1	P49841	GSK3B	S623	P621L	621	Missense	proximal	-2	no	7.097	6.766	EPSD	COSMIC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	Q08050	FOXM1	P49841	GSK3B	S623	W624C	624	Missense	proximal	1	no	7.097	4.876	EPSD	COSMIC	6.007	Loss
CMGC_GSK_GSK3B_ST	Q08050	FOXM1	P49841	GSK3B	T627	P621L	621	Missense	distal	-6	no	6.076	6.054	EPSD	COSMIC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	Q08050	FOXM1	P49841	GSK3B	T627	V632G	632	Missense	distal	5	no	6.076	6.620	EPSD	COSMIC	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	Q08050	FOXM1	P49841	GSK3B	T627	G633E	633	Missense	distal	6	no	6.076	6.073	EPSD	COSMIC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	Q08050	FOXM1	P49841	GSK3B	T627	W624C	624	Missense	distal	-3	no	6.076	6.080	EPSD	COSMIC	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	Q08050	FOXM1	P49841	GSK3B	S638	D636H	636	Missense	proximal	-2	no	9.401	9.312	EPSD	COSMIC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	Q08050	FOXM1	P49841	GSK3B	S638	S643P	643	Missense	distal	5	no	9.401	10.355	EPSD	COSMIC	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	Q08050	FOXM1	P49841	GSK3B	S638	V632G	632	Missense	distal	-6	no	9.401	9.485	EPSD	COSMIC	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	Q08050	FOXM1	P49841	GSK3B	S638	G633E	633	Missense	distal	-5	no	9.401	9.366	EPSD	COSMIC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	Q08050	FOXM1	P49841	GSK3B	T662	P663H	663	Missense	proximal	1	no	8.959	5.258	EPSD	COSMIC	6.007	Loss
CMGC_GSK_GSK3B_ST	Q08050	FOXM1	P49841	GSK3B	T662	L659P	659	Missense	distal	-3	no	8.959	8.832	EPSD	COSMIC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	Q08050	FOXM1	P49841	GSK3B	T662	S666N	666	Missense	distal	4	no	8.959	5.348	EPSD	COSMIC	6.007	Loss
CMGC_GSK_GSK3B_ST	Q08050	FOXM1	P49841	GSK3B	T662	P669L	669	Missense	distal	7	no	8.959	9.008	EPSD	COSMIC	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	Q08050	FOXM1	P49841	GSK3B	S672	P673S	673	Missense	proximal	1	no	6.363	2.518	EPSD	COSMIC	6.007	Loss
CMGC_GSK_GSK3B_ST	Q08050	FOXM1	P49841	GSK3B	S672	R675K	675	Missense	distal	3	no	6.363	6.608	EPSD	COSMIC	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	Q08050	FOXM1	P49841	GSK3B	S672	S666N	666	Missense	distal	-6	no	6.363	6.361	EPSD	COSMIC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	Q08050	FOXM1	P49841	GSK3B	S672	P669L	669	Missense	distal	-3	no	6.363	6.490	EPSD	COSMIC	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	Q08050	FOXM1	P49841	GSK3B	S672	L670P	670	Missense	proximal	-2	no	6.363	6.694	EPSD	COSMIC	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	Q08050	FOXM1	P49841	GSK3B	S695	S695L	695	Missense	central	0	yes	6.118	0.000	EPSD	COSMIC	6.007	Loss
CMGC_GSK_GSK3B_ST	Q08050	FOXM1	P49841	GSK3B	S695	P688S	688	Missense	distal	-7	no	6.118	6.119	EPSD	COSMIC	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	Q08050	FOXM1	P49841	GSK3B	S695	V699I	699	Missense	distal	4	no	6.118	5.186	EPSD	COSMIC	6.007	Loss
CMGC_GSK_GSK3B_ST	P24385	CCND1	P49841	GSK3B	S197	N198S	198	Missense	proximal	1	no	4.901	6.576	EPSD	COSMIC	6.007	Gain
CMGC_GSK_GSK3B_ST	P24385	CCND1	P49841	GSK3B	T286	D292G	292	Missense	distal	6	no	8.992	8.996	PhosphoSitePlus	COSMIC	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	P24385	CCND1	P49841	GSK3B	T286	T286P	286	Missense	central	0	yes	8.992	0.000	PhosphoSitePlus	COSMIC	6.007	Loss
CMGC_GSK_GSK3B_ST	P24385	CCND1	P49841	GSK3B	T286	A284V	284	Missense	proximal	-2	no	8.992	9.294	PhosphoSitePlus	COSMIC	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	P24385	CCND1	P49841	GSK3B	T286	E280V	280	Missense	distal	-6	no	8.992	8.986	PhosphoSitePlus	COSMIC;CCLE	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	P24385	CCND1	P49841	GSK3B	T286	R291W	291	Missense	distal	5	no	8.992	7.690	PhosphoSitePlus	COSMIC;GDSC;CCLE	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	P24385	CCND1	P49841	GSK3B	T286	R291L	291	Missense	distal	5	no	8.992	8.349	PhosphoSitePlus	COSMIC;GDSC;CCLE	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	P24385	CCND1	P49841	GSK3B	T286	V290G	290	Missense	distal	4	no	8.992	8.138	PhosphoSitePlus	COSMIC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	Q07817	BCL2L1	P49841	GSK3B	T115	L112V	112	Missense	distal	-3	no	6.249	6.406	EPSD	COSMIC	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	Q07817	BCL2L1	P49841	GSK3B	T115	G117E	117	Missense	proximal	2	no	6.249	6.419	EPSD	COSMIC	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	Q07817	BCL2L1	P49841	GSK3B	T115	H113Y	113	Missense	proximal	-2	no	6.249	6.035	EPSD	COSMIC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	Q07817	BCL2L1	P49841	GSK3B	T115	A119V	119	Missense	distal	4	no	6.249	6.270	EPSD	COSMIC	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	P41236	PPP1R2	P49841	GSK3B	S24	M25V	25	Missense	proximal	1	no	6.267	6.863	EPSD	COSMIC	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	P41236	PPP1R2	P49841	GSK3B	S24	S28L	28	Missense	distal	4	no	6.267	3.549	EPSD	COSMIC	6.007	Loss
CMGC_GSK_GSK3B_ST	P41236	PPP1R2	P49841	GSK3B	S130	D128G	128	Missense	proximal	-2	no	7.336	7.234	EPSD	COSMIC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	P41236	PPP1R2	P49841	GSK3B	S130	E124V	124	Missense	distal	-6	no	7.336	7.331	EPSD	COSMIC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	P41236	PPP1R2	P49841	GSK3B	T177	G180R	180	Missense	distal	3	no	6.008	5.593	EPSD	COSMIC	6.007	Loss
CMGC_GSK_GSK3B_ST	P41236	PPP1R2	P49841	GSK3B	T177	E181K	181	Missense	distal	4	no	6.008	4.826	EPSD	COSMIC	6.007	Loss
CMGC_GSK_GSK3B_ST	P41236	PPP1R2	P49841	GSK3B	T177	A178V	178	Missense	proximal	1	no	6.008	6.749	EPSD	COSMIC	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	Q16236	NFE2L2	P49841	GSK3B	T211	M212T	212	Missense	proximal	1	no	6.279	6.675	EPSD	COSMIC	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	Q16236	NFE2L2	P49841	GSK3B	T211	T211I	211	Missense	central	0	yes	6.279	0.000	EPSD	COSMIC	6.007	Loss
CMGC_GSK_GSK3B_ST	Q16236	NFE2L2	P49841	GSK3B	T211	M212L	212	Missense	proximal	1	no	6.279	7.005	EPSD	COSMIC	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	Q16236	NFE2L2	P49841	GSK3B	S243	L247I	247	Missense	distal	4	no	6.099	5.495	EPSD	COSMIC	6.007	Loss
CMGC_GSK_GSK3B_ST	Q16236	NFE2L2	P49841	GSK3B	S243	P244A	244	Missense	proximal	1	no	6.099	2.367	EPSD	COSMIC	6.007	Loss
CMGC_GSK_GSK3B_ST	Q16236	NFE2L2	P49841	GSK3B	S243	P244L	244	Missense	proximal	1	no	6.099	3.239	EPSD	COSMIC	6.007	Loss
CMGC_GSK_GSK3B_ST	Q16236	NFE2L2	P49841	GSK3B	S243	E238Q	238	Missense	distal	-5	no	6.099	5.811	EPSD	COSMIC	6.007	Loss
CMGC_GSK_GSK3B_ST	Q16236	NFE2L2	P49841	GSK3B	S243	L247F	247	Missense	distal	4	no	6.099	5.203	EPSD	COSMIC	6.007	Loss
CMGC_GSK_GSK3B_ST	Q16236	NFE2L2	P49841	GSK3B	S243	S243F	243	Missense	central	0	yes	6.099	0.000	EPSD	COSMIC	6.007	Loss
CMGC_GSK_GSK3B_ST	Q16236	NFE2L2	P49841	GSK3B	S347	S353T	353	Missense	distal	6	no	8.774	8.777	PhosphoSitePlus;EPSD	COSMIC	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	Q16236	NFE2L2	P49841	GSK3B	S347	S353N	353	Missense	distal	6	no	8.774	8.768	PhosphoSitePlus;EPSD	COSMIC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	Q16236	NFE2L2	P49841	GSK3B	S347	S353F	353	Missense	distal	6	no	8.774	8.762	PhosphoSitePlus;EPSD	COSMIC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	Q16236	NFE2L2	P49841	GSK3B	S347	S351R	351	Missense	distal	4	no	8.774	5.737	PhosphoSitePlus;EPSD	COSMIC	6.007	Loss
CMGC_GSK_GSK3B_ST	Q16236	NFE2L2	P49841	GSK3B	S351	S353T	353	Missense	proximal	2	no	9.109	9.235	EPSD	COSMIC	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	Q16236	NFE2L2	P49841	GSK3B	S351	S353N	353	Missense	proximal	2	no	9.109	8.577	EPSD	COSMIC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	Q16236	NFE2L2	P49841	GSK3B	S351	A355T	355	Missense	distal	4	no	9.109	10.652	EPSD	COSMIC	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	Q16236	NFE2L2	P49841	GSK3B	S351	S353F	353	Missense	proximal	2	no	9.109	8.764	EPSD	COSMIC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	Q16236	NFE2L2	P49841	GSK3B	S351	S351R	351	Missense	central	0	yes	9.109	0.000	EPSD	COSMIC	6.007	Loss
CMGC_GSK_GSK3B_ST	Q16236	NFE2L2	P49841	GSK3B	S356	S353T	353	Missense	distal	-3	no	10.379	10.404	EPSD	COSMIC	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	Q16236	NFE2L2	P49841	GSK3B	S356	S353N	353	Missense	distal	-3	no	10.379	10.284	EPSD	COSMIC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	Q16236	NFE2L2	P49841	GSK3B	S356	A355T	355	Missense	proximal	-1	no	10.379	10.458	EPSD	COSMIC	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	Q16236	NFE2L2	P49841	GSK3B	S356	S360F	360	Missense	distal	4	no	10.379	6.764	EPSD	COSMIC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	Q16236	NFE2L2	P49841	GSK3B	S356	S353F	353	Missense	distal	-3	no	10.379	10.445	EPSD	COSMIC	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	Q16236	NFE2L2	P49841	GSK3B	S356	S351R	351	Missense	distal	-5	no	10.379	11.076	EPSD	COSMIC	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	Q16236	NFE2L2	P49841	GSK3B	T395	G401E	401	Missense	distal	6	no	8.368	8.365	EPSD	COSMIC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	Q16236	NFE2L2	P49841	GSK3B	T395	G401V	401	Missense	distal	6	no	8.368	8.361	EPSD	COSMIC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	Q16236	NFE2L2	P49841	GSK3B	T395	S399Y	399	Missense	distal	4	no	8.368	4.855	EPSD	COSMIC	6.007	Loss
CMGC_GSK_GSK3B_ST	Q16236	NFE2L2	P49841	GSK3B	T395	G392D	392	Missense	distal	-3	no	8.368	8.418	EPSD	COSMIC	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	Q16236	NFE2L2	P49841	GSK3B	T395	S399F	399	Missense	distal	4	no	8.368	4.754	EPSD	COSMIC	6.007	Loss
CMGC_GSK_GSK3B_ST	Q16236	NFE2L2	P49841	GSK3B	T395	V388A	388	Missense	distal	-7	no	8.368	8.369	EPSD	COSMIC	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	Q16236	NFE2L2	P49841	GSK3B	S408	G412V	412	Missense	distal	4	no	5.368	6.221	EPSD	COSMIC	6.007	Gain
CMGC_GSK_GSK3B_ST	Q16236	NFE2L2	P49841	GSK3B	S410	V404A	404	Missense	distal	-6	no	6.994	7.072	EPSD	COSMIC	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	Q16236	NFE2L2	P49841	GSK3B	S410	S408L	408	Missense	proximal	-2	no	6.994	6.920	EPSD	COSMIC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	Q16236	NFE2L2	P49841	GSK3B	S410	L407F	407	Missense	distal	-3	no	6.994	7.051	EPSD	COSMIC	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	Q16236	NFE2L2	P49841	GSK3B	S410	H416Y	416	Missense	distal	6	no	6.994	6.998	EPSD	COSMIC	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	Q16236	NFE2L2	P49841	GSK3B	S410	M403L	403	Missense	distal	-7	no	6.994	6.973	EPSD	COSMIC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	Q16236	NFE2L2	P49841	GSK3B	S410	V417L	417	Missense	distal	7	no	6.994	6.555	EPSD	COSMIC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	Q16236	NFE2L2	P49841	GSK3B	S410	G412V	412	Missense	proximal	2	no	6.994	6.983	EPSD	COSMIC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	Q16236	NFE2L2	P49841	GSK3B	T425	D419N	419	Missense	distal	-6	no	6.774	6.797	EPSD	COSMIC	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	Q16236	NFE2L2	P49841	GSK3B	T425	E427D	427	Missense	proximal	2	no	6.774	6.953	EPSD	COSMIC	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	Q16236	NFE2L2	P49841	GSK3B	T425	E427K	427	Missense	proximal	2	no	6.774	6.814	EPSD	COSMIC	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	Q16236	NFE2L2	P49841	GSK3B	S433	R437S	437	Missense	distal	4	no	5.225	8.263	EPSD	COSMIC	6.007	Gain
CMGC_GSK_GSK3B_ST	Q16236	NFE2L2	P49841	GSK3B	T439	T439P	439	Missense	central	0	yes	7.309	0.000	EPSD	COSMIC	6.007	Loss
CMGC_GSK_GSK3B_ST	Q16236	NFE2L2	P49841	GSK3B	T439	G435V	435	Missense	distal	-4	no	7.309	6.504	EPSD	COSMIC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	Q16236	NFE2L2	P49841	GSK3B	T439	H446Q	446	Missense	distal	7	no	7.309	6.773	EPSD	COSMIC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	Q16236	NFE2L2	P49841	GSK3B	T439	D444H	444	Missense	distal	5	no	7.309	6.530	EPSD	COSMIC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	Q16236	NFE2L2	P49841	GSK3B	T439	R437S	437	Missense	proximal	-2	no	7.309	7.425	EPSD	COSMIC	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	Q16236	NFE2L2	P49841	GSK3B	S577	E571K	571	Missense	distal	-6	no	8.123	8.122	EPSD	COSMIC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	Q16236	NFE2L2	P49841	GSK3B	S577	E580K	580	Missense	distal	3	no	8.123	8.016	EPSD	COSMIC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	Q16236	NFE2L2	P49841	GSK3B	S577	S577F	577	Missense	central	0	yes	8.123	0.000	EPSD	COSMIC	6.007	Loss
CMGC_GSK_GSK3B_ST	Q16236	NFE2L2	P49841	GSK3B	S577	Y581N	581	Missense	distal	4	no	8.123	8.026	EPSD	COSMIC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	P12524	MYCL	P49841	GSK3B	S38	W45C	45	Missense	distal	7	no	11.170	11.015	PhosphoSitePlus;EPSD	COSMIC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	P12524	MYCL	P49841	GSK3B	S38	K31N	31	Missense	distal	-7	no	11.170	11.154	PhosphoSitePlus;EPSD	COSMIC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	P12524	MYCL	P49841	GSK3B	S42	W45C	45	Missense	distal	3	no	8.597	8.494	EPSD;PhosphoSitePlus	COSMIC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	P13807	GYS1	P49841	GSK3B	S641	A640T	640	Missense	proximal	-1	no	12.074	12.153	EPSD	COSMIC	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	P13807	GYS1	P49841	GSK3B	S641	P646S	646	Missense	distal	5	no	12.074	11.120	EPSD	COSMIC;CCLE	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	P13807	GYS1	P49841	GSK3B	S641	Y636C	636	Missense	distal	-5	no	12.074	11.941	EPSD	COSMIC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	P13807	GYS1	P49841	GSK3B	S645	A640T	640	Missense	distal	-5	no	12.415	12.426	EPSD;PhosphoSitePlus	COSMIC	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	P13807	GYS1	P49841	GSK3B	S645	P646S	646	Missense	proximal	1	no	12.415	8.570	EPSD;PhosphoSitePlus	COSMIC;CCLE	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	P13807	GYS1	P49841	GSK3B	S649	S653C	653	Missense	distal	4	no	9.204	3.071	EPSD	COSMIC	6.007	Loss
CMGC_GSK_GSK3B_ST	P13807	GYS1	P49841	GSK3B	S649	P646S	646	Missense	distal	-3	no	9.204	9.321	EPSD	COSMIC;CCLE	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	P13807	GYS1	P49841	GSK3B	S649	P654L	654	Missense	distal	5	no	9.204	7.923	EPSD	COSMIC;CCLE	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	P13807	GYS1	P49841	GSK3B	S653	S653C	653	Missense	central	0	yes	11.919	0.000	PhosphoSitePlus;EPSD	COSMIC	6.007	Loss
CMGC_GSK_GSK3B_ST	P13807	GYS1	P49841	GSK3B	S653	P646S	646	Missense	distal	-7	no	11.919	11.921	PhosphoSitePlus;EPSD	COSMIC;CCLE	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	P13807	GYS1	P49841	GSK3B	S653	P654L	654	Missense	proximal	1	no	11.919	9.058	PhosphoSitePlus;EPSD	COSMIC;CCLE	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	P13807	GYS1	P49841	GSK3B	T700	A697V	697	Missense	distal	-3	no	5.965	6.112	EPSD	COSMIC	6.007	Gain
CMGC_GSK_GSK3B_ST	P13807	GYS1	P49841	GSK3B	S702	A697V	697	Missense	distal	-5	no	6.339	6.641	EPSD	COSMIC	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	P13807	GYS1	P49841	GSK3B	S716	T713M	713	Missense	distal	-3	no	6.141	6.087	EPSD	COSMIC;CCLE	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	P13807	GYS1	P49841	GSK3B	S717	T713M	713	Missense	distal	-4	no	7.454	6.730	EPSD	COSMIC;CCLE	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	P13807	GYS1	P49841	GSK3B	S720	T713M	713	Missense	distal	-7	no	6.874	6.868	EPSD	COSMIC;CCLE	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	P13807	GYS1	P49841	GSK3B	S727	E734K	734	Missense	distal	7	no	10.797	10.689	EPSD	COSMIC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	P13807	GYS1	P49841	GSK3B	S731	E735Q	735	Missense	distal	4	no	7.096	5.554	EPSD	COSMIC	6.007	Loss
CMGC_GSK_GSK3B_ST	P13807	GYS1	P49841	GSK3B	S731	E734K	734	Missense	distal	3	no	7.096	6.989	EPSD	COSMIC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	P49716	CEBPD	P49841	GSK3B	S133	A137S	137	Missense	distal	4	no	5.929	8.341	EPSD	COSMIC	6.007	Gain
CMGC_GSK_GSK3B_ST	P49716	CEBPD	P49841	GSK3B	S167	P172H	172	Missense	distal	5	no	9.108	7.481	PhosphoSitePlus	COSMIC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	P49716	CEBPD	P49841	GSK3B	T171	R178W	178	Missense	distal	7	no	6.438	6.547	EPSD	COSMIC	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	P49716	CEBPD	P49841	GSK3B	T171	P172H	172	Missense	proximal	1	no	6.438	2.737	EPSD	COSMIC	6.007	Loss
CMGC_GSK_GSK3B_ST	P49716	CEBPD	P49841	GSK3B	S191	P187Q	187	Missense	distal	-4	no	6.452	6.186	EPSD	COSMIC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	P49716	CEBPD	P49841	GSK3B	S256	F251L	251	Missense	distal	-5	no	10.967	10.517	EPSD	COSMIC;GDSC;CCLE	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	P13051	UNG	P49841	GSK3B	S12	A16S	16	Missense	distal	4	no	7.468	9.880	EPSD	COSMIC	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	P13051	UNG	P49841	GSK3B	S12	R19L	19	Missense	distal	7	no	7.468	7.016	EPSD	COSMIC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	P13051	UNG	P49841	GSK3B	S12	P15L	15	Missense	distal	3	no	7.468	7.150	EPSD	COSMIC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	P13051	UNG	P49841	GSK3B	S14	A16S	16	Missense	proximal	2	no	7.637	7.629	EPSD	COSMIC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	P13051	UNG	P49841	GSK3B	S14	R19L	19	Missense	distal	5	no	7.637	6.994	EPSD	COSMIC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	P13051	UNG	P49841	GSK3B	S14	P15L	15	Missense	proximal	1	no	7.637	4.776	EPSD	COSMIC	6.007	Loss
CMGC_GSK_GSK3B_ST	P13051	UNG	P49841	GSK3B	S23	A16S	16	Missense	distal	-7	no	8.355	8.333	EPSD	COSMIC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	P13051	UNG	P49841	GSK3B	S23	R19L	19	Missense	distal	-4	no	8.355	8.192	EPSD	COSMIC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	P13051	UNG	P49841	GSK3B	T60	P61S	61	Missense	proximal	1	no	10.640	6.795	EPSD;PhosphoSitePlus	COSMIC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	P13051	UNG	P49841	GSK3B	S63	P61S	61	Missense	proximal	-2	no	6.113	5.856	EPSD	COSMIC	6.007	Loss
CMGC_GSK_GSK3B_ST	P13051	UNG	P49841	GSK3B	S64	P61S	61	Missense	distal	-3	no	8.358	8.475	PhosphoSitePlus;EPSD	COSMIC	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	P13051	UNG	P49841	GSK3B	S279	Q274L	274	Missense	distal	-5	no	8.076	8.042	EPSD	COSMIC;CCLE	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	P13051	UNG	P49841	GSK3B	S279	L281F	281	Missense	proximal	2	no	8.076	7.672	EPSD	COSMIC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	P13051	UNG	P49841	GSK3B	S279	V272G	272	Missense	distal	-7	no	8.076	8.053	EPSD	COSMIC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	P13051	UNG	P49841	GSK3B	S279	H277R	277	Missense	proximal	-2	no	8.076	8.066	EPSD	COSMIC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	Q14494	NFE2L1	P49841	GSK3B	S112	P118L	118	Missense	distal	6	no	7.059	7.052	EPSD	COSMIC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	Q14494	NFE2L1	P49841	GSK3B	S116	L122I	122	Missense	distal	6	no	8.993	8.998	EPSD	COSMIC	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	Q14494	NFE2L1	P49841	GSK3B	S116	P118L	118	Missense	proximal	2	no	8.993	8.609	EPSD	COSMIC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	Q14494	NFE2L1	P49841	GSK3B	S379	Q373E	373	Missense	distal	-6	no	7.123	7.066	PhosphoSitePlus	COSMIC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	Q14494	NFE2L1	P49841	GSK3B	S379	L377M	377	Missense	proximal	-2	no	7.123	6.867	PhosphoSitePlus	COSMIC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	Q14494	NFE2L1	P49841	GSK3B	S500	S500C	500	Missense	central	0	yes	7.860	0.000	EPSD	COSMIC	6.007	Loss
CMGC_GSK_GSK3B_ST	Q14494	NFE2L1	P49841	GSK3B	S500	S497T	497	Missense	distal	-3	no	7.860	7.885	EPSD	COSMIC	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	Q14494	NFE2L1	P49841	GSK3B	S500	S500F	500	Missense	central	0	yes	7.860	0.000	EPSD	COSMIC	6.007	Loss
CMGC_GSK_GSK3B_ST	Q14494	NFE2L1	P49841	GSK3B	S500	S498C	498	Missense	proximal	-2	no	7.860	7.549	EPSD	COSMIC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	Q14494	NFE2L1	P49841	GSK3B	S501	S500C	500	Missense	proximal	-1	no	7.603	7.567	EPSD	COSMIC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	Q14494	NFE2L1	P49841	GSK3B	S501	S497T	497	Missense	distal	-4	no	7.603	7.267	EPSD	COSMIC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	Q14494	NFE2L1	P49841	GSK3B	S501	S500F	500	Missense	proximal	-1	no	7.603	7.472	EPSD	COSMIC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	Q14494	NFE2L1	P49841	GSK3B	S501	S498C	498	Missense	distal	-3	no	7.603	7.706	EPSD	COSMIC	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	Q14494	NFE2L1	P49841	GSK3B	S502	S500C	500	Missense	proximal	-2	no	6.810	6.498	EPSD	COSMIC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	Q14494	NFE2L1	P49841	GSK3B	S502	S509C	509	Missense	distal	7	no	6.810	7.202	EPSD	COSMIC	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	Q14494	NFE2L1	P49841	GSK3B	S502	S497T	497	Missense	distal	-5	no	6.810	7.099	EPSD	COSMIC	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	Q14494	NFE2L1	P49841	GSK3B	S502	S500F	500	Missense	proximal	-2	no	6.810	6.479	EPSD	COSMIC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	Q14494	NFE2L1	P49841	GSK3B	S502	S498C	498	Missense	distal	-4	no	6.810	4.695	EPSD	COSMIC	6.007	Loss
CMGC_GSK_GSK3B_ST	Q14494	NFE2L1	P49841	GSK3B	S507	S500C	500	Missense	distal	-7	no	7.582	7.604	EPSD	COSMIC	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	Q14494	NFE2L1	P49841	GSK3B	S507	S511F	511	Missense	distal	4	no	7.582	3.967	EPSD	COSMIC	6.007	Loss
CMGC_GSK_GSK3B_ST	Q14494	NFE2L1	P49841	GSK3B	S507	S509C	509	Missense	proximal	2	no	7.582	7.089	EPSD	COSMIC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	Q14494	NFE2L1	P49841	GSK3B	S507	A514T	514	Missense	distal	7	no	7.582	7.175	EPSD	COSMIC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	Q14494	NFE2L1	P49841	GSK3B	S507	S500F	500	Missense	distal	-7	no	7.582	7.592	EPSD	COSMIC	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	Q14494	NFE2L1	P49841	GSK3B	S508	S511F	511	Missense	distal	3	no	6.503	6.293	EPSD	COSMIC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	Q14494	NFE2L1	P49841	GSK3B	S508	S509C	509	Missense	proximal	1	no	6.503	6.025	EPSD	COSMIC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	Q14494	NFE2L1	P49841	GSK3B	S508	A514T	514	Missense	distal	6	no	6.503	6.507	EPSD	COSMIC	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	Q14494	NFE2L1	P49841	GSK3B	S509	S511F	511	Missense	proximal	2	no	6.369	6.024	EPSD	COSMIC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	Q14494	NFE2L1	P49841	GSK3B	S509	S509C	509	Missense	central	0	yes	6.369	0.000	EPSD	COSMIC	6.007	Loss
CMGC_GSK_GSK3B_ST	Q14494	NFE2L1	P49841	GSK3B	S509	A514T	514	Missense	distal	5	no	6.369	6.421	EPSD	COSMIC	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	Q14494	NFE2L1	P49841	GSK3B	S734	R731Q	731	Missense	distal	-3	no	6.182	6.044	EPSD	COSMIC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	Q14494	NFE2L1	P49841	GSK3B	S734	R731W	731	Missense	distal	-3	no	6.182	6.113	EPSD	COSMIC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	Q14494	NFE2L1	P49841	GSK3B	S734	D727N	727	Missense	distal	-7	no	6.182	6.186	EPSD	COSMIC	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	Q14494	NFE2L1	P49841	GSK3B	S734	A739V	739	Missense	distal	5	no	6.182	5.756	EPSD	COSMIC;GDSC;CCLE	6.007	Loss
CMGC_GSK_GSK3B_ST	Q7KZI7	MARK2	P49841	GSK3B	T6	E13K	13	Missense	distal	7	no	7.643	7.535	EPSD	COSMIC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	Q7KZI7	MARK2	P49841	GSK3B	T6	S2C	2	Missense	distal	-4	no	7.643	5.529	EPSD	COSMIC	6.007	Loss
CMGC_GSK_GSK3B_ST	Q7KZI7	MARK2	P49841	GSK3B	S26	L24V	24	Missense	proximal	-2	no	6.609	6.650	EPSD	COSMIC	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	Q7KZI7	MARK2	P49841	GSK3B	T208	T201P	201	Missense	distal	-7	no	6.055	6.026	EPSD	COSMIC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	Q7KZI7	MARK2	P49841	GSK3B	T208	P213S	213	Missense	distal	5	no	6.055	5.101	EPSD	COSMIC	6.007	Loss
CMGC_GSK_GSK3B_ST	Q7KZI7	MARK2	P49841	GSK3B	S212	P213S	213	Missense	proximal	1	no	11.034	7.189	PhosphoSitePlus	COSMIC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	Q7KZI7	MARK2	P49841	GSK3B	S212	A216D	216	Missense	distal	4	no	11.034	11.022	PhosphoSitePlus	COSMIC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	Q7KZI7	MARK2	P49841	GSK3B	S456	E462D	462	Missense	distal	6	no	6.831	6.830	EPSD	COSMIC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	Q7KZI7	MARK2	P49841	GSK3B	S456	S449N	449	Missense	distal	-7	no	6.831	6.837	EPSD	COSMIC	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	Q7KZI7	MARK2	P49841	GSK3B	S456	P457L	457	Missense	proximal	1	no	6.831	3.971	EPSD	COSMIC	6.007	Loss
CMGC_GSK_GSK3B_ST	Q7KZI7	MARK2	P49841	GSK3B	S456	P457H	457	Missense	proximal	1	no	6.831	3.131	EPSD	COSMIC	6.007	Loss
CMGC_GSK_GSK3B_ST	Q7KZI7	MARK2	P49841	GSK3B	T466	P470S	470	Missense	distal	4	no	3.582	6.553	EPSD	COSMIC	6.007	Gain
CMGC_GSK_GSK3B_ST	Q7KZI7	MARK2	P49841	GSK3B	T467	P470S	470	Missense	distal	3	no	7.070	7.053	EPSD	COSMIC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	Q7KZI7	MARK2	P49841	GSK3B	T467	E462D	462	Missense	distal	-5	no	7.070	6.912	EPSD	COSMIC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	Q7KZI7	MARK2	P49841	GSK3B	T467	K464N	464	Missense	distal	-3	no	7.070	6.952	EPSD	COSMIC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	Q7KZI7	MARK2	P49841	GSK3B	S474	P470S	470	Missense	distal	-4	no	6.750	7.314	EPSD	COSMIC	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	Q7KZI7	MARK2	P49841	GSK3B	S474	S477F	477	Missense	distal	3	no	6.750	6.539	EPSD	COSMIC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	Q7KZI7	MARK2	P49841	GSK3B	S511	S514F	514	Missense	distal	3	no	8.993	8.782	EPSD	COSMIC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	Q7KZI7	MARK2	P49841	GSK3B	S511	A518T	518	Missense	distal	7	no	8.993	8.586	EPSD	COSMIC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	Q7KZI7	MARK2	P49841	GSK3B	S511	G510V	510	Missense	proximal	-1	no	8.993	9.034	EPSD	COSMIC	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	Q7KZI7	MARK2	P49841	GSK3B	S511	M508I	508	Missense	distal	-3	no	8.993	9.134	EPSD	COSMIC	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	Q7KZI7	MARK2	P49841	GSK3B	S514	A518T	518	Missense	distal	4	no	5.032	6.575	EPSD	COSMIC	6.007	Gain
CMGC_GSK_GSK3B_ST	Q7KZI7	MARK2	P49841	GSK3B	T515	S514F	514	Missense	proximal	-1	no	6.622	6.492	EPSD	COSMIC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	Q7KZI7	MARK2	P49841	GSK3B	T515	A518T	518	Missense	distal	3	no	6.622	6.927	EPSD	COSMIC	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	Q7KZI7	MARK2	P49841	GSK3B	T515	G510V	510	Missense	distal	-5	no	6.622	6.736	EPSD	COSMIC	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	Q7KZI7	MARK2	P49841	GSK3B	T515	M508I	508	Missense	distal	-7	no	6.622	6.629	EPSD	COSMIC	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	Q7KZI7	MARK2	P49841	GSK3B	S523	P527S	527	Missense	distal	4	no	3.845	6.816	EPSD	COSMIC	6.007	Gain
CMGC_GSK_GSK3B_ST	Q7KZI7	MARK2	P49841	GSK3B	S533	P540L	540	Missense	distal	7	no	6.136	6.185	EPSD	COSMIC	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	Q7KZI7	MARK2	P49841	GSK3B	S533	R526W	526	Missense	distal	-7	no	6.136	6.146	EPSD	COSMIC	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	Q7KZI7	MARK2	P49841	GSK3B	S533	P527S	527	Missense	distal	-6	no	6.136	6.115	EPSD	COSMIC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	Q7KZI7	MARK2	P49841	GSK3B	S533	P527Q	527	Missense	distal	-6	no	6.136	6.111	EPSD	COSMIC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	Q7KZI7	MARK2	P49841	GSK3B	S533	A536V	536	Missense	distal	3	no	6.136	6.265	EPSD	COSMIC	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	Q7KZI7	MARK2	P49841	GSK3B	S533	S535F	535	Missense	proximal	2	no	6.136	5.791	EPSD	COSMIC	6.007	Loss
CMGC_GSK_GSK3B_ST	Q7KZI7	MARK2	P49841	GSK3B	S544	P548S	548	Missense	distal	4	no	3.495	6.466	EPSD	COSMIC	6.007	Gain
CMGC_GSK_GSK3B_ST	Q7KZI7	MARK2	P49841	GSK3B	T616	G614S	614	Missense	proximal	-2	no	7.288	7.406	EPSD	COSMIC	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	Q7KZI7	MARK2	P49841	GSK3B	T616	P617S	617	Missense	proximal	1	no	7.288	3.443	EPSD	COSMIC	6.007	Loss
CMGC_GSK_GSK3B_ST	Q7KZI7	MARK2	P49841	GSK3B	S698	R691H	691	Missense	distal	-7	no	6.595	6.594	EPSD	COSMIC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	Q7KZI7	MARK2	P49841	GSK3B	S698	R691L	691	Missense	distal	-7	no	6.595	6.576	EPSD	COSMIC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	Q7KZI7	MARK2	P49841	GSK3B	S698	R691C	691	Missense	distal	-7	no	6.595	6.599	EPSD	COSMIC	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	Q7KZI7	MARK2	P49841	GSK3B	S698	T696M	696	Missense	proximal	-2	no	6.595	6.236	EPSD	COSMIC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	O00327	ARNTL	P49841	GSK3B	S17	T21S	21	Missense	distal	4	no	10.639	11.508	EPSD;PhosphoSitePlus	COSMIC	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	O00327	ARNTL	P49841	GSK3B	S17	P20T	20	Missense	distal	3	no	10.639	10.589	EPSD;PhosphoSitePlus	COSMIC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	O00327	ARNTL	P49841	GSK3B	S17	S17F	17	Missense	central	0	yes	10.639	0.000	EPSD;PhosphoSitePlus	COSMIC	6.007	Loss
CMGC_GSK_GSK3B_ST	O00327	ARNTL	P49841	GSK3B	T21	P20T	20	Missense	proximal	-1	no	7.717	7.586	PhosphoSitePlus;EPSD	COSMIC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	O00327	ARNTL	P49841	GSK3B	T21	S27Y	27	Missense	distal	6	no	7.717	7.711	PhosphoSitePlus;EPSD	COSMIC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	O00327	ARNTL	P49841	GSK3B	T21	S17F	17	Missense	distal	-4	no	7.717	6.563	PhosphoSitePlus;EPSD	COSMIC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	O00327	ARNTL	P49841	GSK3B	S515	S519N	519	Missense	distal	4	no	7.085	3.475	EPSD	COSMIC	6.007	Loss
CMGC_GSK_GSK3B_ST	O00327	ARNTL	P49841	GSK3B	S515	S513F	513	Missense	proximal	-2	no	7.085	6.755	EPSD	COSMIC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	O00327	ARNTL	P49841	GSK3B	S515	G511E	511	Missense	distal	-4	no	7.085	6.916	EPSD	COSMIC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	O00327	ARNTL	P49841	GSK3B	S515	S520N	520	Missense	distal	5	no	7.085	6.765	EPSD	COSMIC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	O00327	ARNTL	P49841	GSK3B	S515	S515F	515	Missense	central	0	yes	7.085	0.000	EPSD	COSMIC	6.007	Loss
CMGC_GSK_GSK3B_ST	O00327	ARNTL	P49841	GSK3B	S516	S519N	519	Missense	distal	3	no	7.707	7.756	EPSD	COSMIC	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	O00327	ARNTL	P49841	GSK3B	S516	S513F	513	Missense	distal	-3	no	7.707	7.774	EPSD	COSMIC	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	O00327	ARNTL	P49841	GSK3B	S516	G511E	511	Missense	distal	-5	no	7.707	7.672	EPSD	COSMIC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	O00327	ARNTL	P49841	GSK3B	S516	S520N	520	Missense	distal	4	no	7.707	4.097	EPSD	COSMIC	6.007	Loss
CMGC_GSK_GSK3B_ST	O00327	ARNTL	P49841	GSK3B	S516	S515F	515	Missense	proximal	-1	no	7.707	7.577	EPSD	COSMIC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	O00327	ARNTL	P49841	GSK3B	S520	S519N	519	Missense	proximal	-1	no	6.514	6.576	EPSD	COSMIC	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	O00327	ARNTL	P49841	GSK3B	S520	S513F	513	Missense	distal	-7	no	6.514	6.524	EPSD	COSMIC	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	O00327	ARNTL	P49841	GSK3B	S520	T527M	527	Missense	distal	7	no	6.514	6.942	EPSD	COSMIC	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	O00327	ARNTL	P49841	GSK3B	S520	S520N	520	Missense	central	0	yes	6.514	0.000	EPSD	COSMIC	6.007	Loss
CMGC_GSK_GSK3B_ST	O00327	ARNTL	P49841	GSK3B	S520	S515F	515	Missense	distal	-5	no	6.514	7.074	EPSD	COSMIC	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	O00327	ARNTL	P49841	GSK3B	T527	S533F	533	Missense	distal	6	no	8.139	8.127	EPSD	COSMIC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	O00327	ARNTL	P49841	GSK3B	T527	T527M	527	Missense	central	0	yes	8.139	0.000	EPSD	COSMIC	6.007	Loss
CMGC_GSK_GSK3B_ST	O00327	ARNTL	P49841	GSK3B	T527	S520N	520	Missense	distal	-7	no	8.139	8.145	EPSD	COSMIC	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	O00327	ARNTL	P49841	GSK3B	T527	S534F	534	Missense	distal	7	no	8.139	8.217	EPSD	COSMIC	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	O00327	ARNTL	P49841	GSK3B	S592	S590T	590	Missense	proximal	-2	no	6.736	6.763	EPSD	COSMIC	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	O00327	ARNTL	P49841	GSK3B	S592	N595S	595	Missense	distal	3	no	6.736	6.688	EPSD	COSMIC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	O00327	ARNTL	P49841	GSK3B	S592	S591T	591	Missense	proximal	-1	no	6.736	6.661	EPSD	COSMIC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	O00327	ARNTL	P49841	GSK3B	S592	A598T	598	Missense	distal	6	no	6.736	6.740	EPSD	COSMIC	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	Q13887	KLF5	P49841	GSK3B	S303	P304T	304	Missense	proximal	1	no	12.612	9.421	PhosphoSitePlus	COSMIC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	Q13887	KLF5	P49841	GSK3B	S303	P304Q	304	Missense	proximal	1	no	12.612	9.344	PhosphoSitePlus	COSMIC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	Q13887	KLF5	P49841	GSK3B	S303	A297V	297	Missense	distal	-6	no	12.612	12.534	PhosphoSitePlus	COSMIC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	Q13887	KLF5	P49841	GSK3B	S303	P301H	301	Missense	proximal	-2	no	12.612	12.251	PhosphoSitePlus	COSMIC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	Q13887	KLF5	P49841	GSK3B	S303	S303P	303	Missense	central	0	yes	12.612	0.000	PhosphoSitePlus	COSMIC	6.007	Loss
CMGC_GSK_GSK3B_ST	Q13887	KLF5	P49841	GSK3B	S303	F300V	300	Missense	distal	-3	no	12.612	12.713	PhosphoSitePlus	COSMIC	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	Q13887	KLF5	P49841	GSK3B	S303	P301L	301	Missense	proximal	-2	no	12.612	12.282	PhosphoSitePlus	COSMIC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	Q13887	KLF5	P49841	GSK3B	S303	P304A	304	Missense	proximal	1	no	12.612	8.880	PhosphoSitePlus	COSMIC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	Q13887	KLF5	P49841	GSK3B	S303	G310V	310	Missense	distal	7	no	12.612	13.018	PhosphoSitePlus	COSMIC	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	Q13887	KLF5	P49841	GSK3B	S303	S303L	303	Missense	central	0	yes	12.612	0.000	PhosphoSitePlus	COSMIC	6.007	Loss
CMGC_GSK_GSK3B_ST	Q13887	KLF5	P49841	GSK3B	S303	P302R	302	Missense	proximal	-1	no	12.612	12.419	PhosphoSitePlus	COSMIC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	Q13887	KLF5	P49841	GSK3B	S303	P305A	305	Missense	proximal	2	no	12.612	12.176	PhosphoSitePlus	COSMIC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	Q13887	KLF5	P49841	GSK3B	T323	E317D	317	Missense	distal	-6	no	7.049	7.085	EPSD	COSMIC;CCLE	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	Q13887	KLF5	P49841	GSK3B	T323	M318K	318	Missense	distal	-5	no	7.049	6.947	EPSD	COSMIC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	Q13887	KLF5	P49841	GSK3B	T396	H397P	397	Missense	proximal	1	no	3.109	6.809	EPSD	COSMIC	6.007	Gain
CMGC_GSK_GSK3B_ST	Q13887	KLF5	P49841	GSK3B	S441	R444H	444	Missense	distal	3	no	6.012	6.354	EPSD	COSMIC	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	Q13887	KLF5	P49841	GSK3B	S445	R444H	444	Missense	proximal	-1	no	7.376	7.462	EPSD	COSMIC	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	O15516	CLOCK	P49841	GSK3B	S177	E176Q	176	Missense	proximal	-1	no	7.065	6.970	EPSD	COSMIC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	O15516	CLOCK	P49841	GSK3B	S394	L395I	395	Missense	proximal	1	no	6.883	5.862	EPSD	COSMIC	6.007	Loss
CMGC_GSK_GSK3B_ST	O15516	CLOCK	P49841	GSK3B	S394	L395F	395	Missense	proximal	1	no	6.883	5.513	EPSD	COSMIC	6.007	Loss
CMGC_GSK_GSK3B_ST	O15516	CLOCK	P49841	GSK3B	S427	S433P	433	Missense	distal	6	no	9.116	9.118	PhosphoSitePlus	COSMIC	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	O15516	CLOCK	P49841	GSK3B	S427	T429A	429	Missense	proximal	2	no	9.116	8.997	PhosphoSitePlus	COSMIC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	O15516	CLOCK	P49841	GSK3B	S427	R423G	423	Missense	distal	-4	no	9.116	9.874	PhosphoSitePlus	COSMIC	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	O15516	CLOCK	P49841	GSK3B	T429	S433P	433	Missense	distal	4	no	7.798	4.827	EPSD	COSMIC	6.007	Loss
CMGC_GSK_GSK3B_ST	O15516	CLOCK	P49841	GSK3B	T429	T429A	429	Missense	central	0	yes	7.798	0.000	EPSD	COSMIC	6.007	Loss
CMGC_GSK_GSK3B_ST	O15516	CLOCK	P49841	GSK3B	T429	R423G	423	Missense	distal	-6	no	7.798	7.871	EPSD	COSMIC	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	O15516	CLOCK	P49841	GSK3B	S433	S433P	433	Missense	central	0	yes	7.203	0.000	EPSD	COSMIC	6.007	Loss
CMGC_GSK_GSK3B_ST	O15516	CLOCK	P49841	GSK3B	S433	T429A	429	Missense	distal	-4	no	7.203	6.379	EPSD	COSMIC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	O15516	CLOCK	P49841	GSK3B	S433	R435Q	435	Missense	proximal	2	no	7.203	7.408	EPSD	COSMIC;GDSC;CCLE	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	O15516	CLOCK	P49841	GSK3B	S437	S433P	433	Missense	distal	-4	no	7.996	7.433	EPSD	COSMIC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	O15516	CLOCK	P49841	GSK3B	S437	R435Q	435	Missense	proximal	-2	no	7.996	8.067	EPSD	COSMIC;GDSC;CCLE	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	O15516	CLOCK	P49841	GSK3B	T451	P456S	456	Missense	distal	5	no	7.186	6.232	EPSD	COSMIC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	O15516	CLOCK	P49841	GSK3B	T451	T457M	457	Missense	distal	6	no	7.186	7.178	EPSD	COSMIC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	O15516	CLOCK	P49841	GSK3B	T457	S460N	460	Missense	distal	3	no	7.371	7.419	EPSD	COSMIC	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	O15516	CLOCK	P49841	GSK3B	T457	P456S	456	Missense	proximal	-1	no	7.371	7.314	EPSD	COSMIC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	O15516	CLOCK	P49841	GSK3B	T457	T457M	457	Missense	central	0	yes	7.371	0.000	EPSD	COSMIC	6.007	Loss
CMGC_GSK_GSK3B_ST	O15516	CLOCK	P49841	GSK3B	T457	R464K	464	Missense	distal	7	no	7.371	6.864	EPSD	COSMIC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	O15516	CLOCK	P49841	GSK3B	S836	D839N	839	Missense	distal	3	no	6.348	6.302	EPSD	COSMIC;GDSC;CCLE	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	P10914	IRF1	P49841	GSK3B	T180	P185L	185	Missense	distal	5	no	11.204	9.923	PhosphoSitePlus	COSMIC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	P30281	CCND3	P49841	GSK3B	S133	P134A	134	Missense	proximal	1	no	8.166	4.433	EPSD	COSMIC	6.007	Loss
CMGC_GSK_GSK3B_ST	P30281	CCND3	P49841	GSK3B	S133	A131V	131	Missense	proximal	-2	no	8.166	8.468	EPSD	COSMIC	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	P30281	CCND3	P49841	GSK3B	S133	L137V	137	Missense	distal	4	no	8.166	8.494	EPSD	COSMIC	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	P30281	CCND3	P49841	GSK3B	S133	S133L	133	Missense	central	0	yes	8.166	0.000	EPSD	COSMIC	6.007	Loss
CMGC_GSK_GSK3B_ST	P30281	CCND3	P49841	GSK3B	S259	E253D	253	Missense	distal	-6	no	7.159	7.196	EPSD	COSMIC	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	P30281	CCND3	P49841	GSK3B	S259	R256K	256	Missense	distal	-3	no	7.159	7.014	EPSD	COSMIC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	P30281	CCND3	P49841	GSK3B	S264	K268E	268	Missense	distal	4	no	6.434	7.616	EPSD	COSMIC	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	P30281	CCND3	P49841	GSK3B	S264	P267L	267	Missense	distal	3	no	6.434	6.116	EPSD	COSMIC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	P30281	CCND3	P49841	GSK3B	S275	K268E	268	Missense	distal	-7	no	6.457	6.468	EPSD	COSMIC	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	P30281	CCND3	P49841	GSK3B	S275	G277W	277	Missense	proximal	2	no	6.457	6.303	EPSD	COSMIC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	P30281	CCND3	P49841	GSK3B	S279	P284S	284	Missense	distal	5	no	7.717	6.763	EPSD	COSMIC;CCLE	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	P30281	CCND3	P49841	GSK3B	S279	P284L	284	Missense	distal	5	no	7.717	6.437	EPSD	COSMIC;CCLE	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	P30281	CCND3	P49841	GSK3B	S279	T283I	283	Missense	distal	4	no	7.717	5.264	EPSD	COSMIC;GDSC;CCLE	6.007	Loss
CMGC_GSK_GSK3B_ST	P30281	CCND3	P49841	GSK3B	S279	P284R	284	Missense	distal	5	no	7.717	7.080	EPSD	COSMIC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	P30281	CCND3	P49841	GSK3B	S279	D286G	286	Missense	distal	7	no	7.717	7.683	EPSD	COSMIC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	P30281	CCND3	P49841	GSK3B	S279	P284T	284	Missense	distal	5	no	7.717	6.741	EPSD	COSMIC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	P30281	CCND3	P49841	GSK3B	S279	G277W	277	Missense	proximal	-2	no	7.717	7.925	EPSD	COSMIC	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	P30281	CCND3	P49841	GSK3B	T283	P284S	284	Missense	proximal	1	no	7.524	3.679	PhosphoSitePlus	COSMIC;CCLE	6.007	Loss
CMGC_GSK_GSK3B_ST	P30281	CCND3	P49841	GSK3B	T283	P284L	284	Missense	proximal	1	no	7.524	4.664	PhosphoSitePlus	COSMIC;CCLE	6.007	Loss
CMGC_GSK_GSK3B_ST	P30281	CCND3	P49841	GSK3B	T283	I290R	290	Missense	distal	7	no	7.524	7.626	PhosphoSitePlus	COSMIC;CCLE	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	P30281	CCND3	P49841	GSK3B	T283	T283I	283	Missense	central	0	yes	7.524	0.000	PhosphoSitePlus	COSMIC;GDSC;CCLE	6.007	Loss
CMGC_GSK_GSK3B_ST	P30281	CCND3	P49841	GSK3B	T283	V287G	287	Missense	distal	4	no	7.524	6.671	PhosphoSitePlus	COSMIC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	P30281	CCND3	P49841	GSK3B	T283	P284R	284	Missense	proximal	1	no	7.524	5.204	PhosphoSitePlus	COSMIC	6.007	Loss
CMGC_GSK_GSK3B_ST	P30281	CCND3	P49841	GSK3B	T283	D286G	286	Missense	distal	3	no	7.524	7.473	PhosphoSitePlus	COSMIC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	P30281	CCND3	P49841	GSK3B	T283	V287D	287	Missense	distal	4	no	7.524	7.490	PhosphoSitePlus	COSMIC;CCLE	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	P30281	CCND3	P49841	GSK3B	T283	P284T	284	Missense	proximal	1	no	7.524	4.333	PhosphoSitePlus	COSMIC	6.007	Loss
CMGC_GSK_GSK3B_ST	P30281	CCND3	P49841	GSK3B	T283	G277W	277	Missense	distal	-6	no	7.524	7.478	PhosphoSitePlus	COSMIC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	P30281	CCND3	P49841	GSK3B	T283	A289P	289	Missense	distal	6	no	7.524	7.528	PhosphoSitePlus	COSMIC	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	P30281	CCND3	P49841	GSK3B	T288	A289P	289	Missense	proximal	1	no	2.857	6.589	EPSD	COSMIC	6.007	Gain
CMGC_GSK_GSK3B_ST	P53805	RCAN1	P49841	GSK3B	S163	P169L	169	Missense	distal	6	no	12.223	12.216	PhosphoSitePlus	COSMIC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	P53805	RCAN1	P49841	GSK3B	S163	P168L	168	Missense	distal	5	no	12.223	10.942	PhosphoSitePlus	COSMIC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	P53805	RCAN1	P49841	GSK3B	S163	P165L	165	Missense	proximal	2	no	12.223	11.839	PhosphoSitePlus	COSMIC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	P53805	RCAN1	P49841	GSK3B	S167	P169L	169	Missense	proximal	2	no	6.637	6.253	EPSD	COSMIC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	P53805	RCAN1	P49841	GSK3B	S167	P168L	168	Missense	proximal	1	no	6.637	3.777	EPSD	COSMIC	6.007	Loss
CMGC_GSK_GSK3B_ST	P53805	RCAN1	P49841	GSK3B	S167	P165L	165	Missense	proximal	-2	no	6.637	6.307	EPSD	COSMIC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	P53805	RCAN1	P49841	GSK3B	T208	A203V	203	Missense	distal	-5	no	6.191	6.494	EPSD	COSMIC	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	P53805	RCAN1	P49841	GSK3B	T208	A203S	203	Missense	distal	-5	no	6.191	5.914	EPSD	COSMIC	6.007	Loss
CMGC_GSK_GSK3B_ST	P53805	RCAN1	P49841	GSK3B	T208	V215I	215	Missense	distal	7	no	6.191	6.102	EPSD	COSMIC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	P53805	RCAN1	P49841	GSK3B	T208	A204V	204	Missense	distal	-4	no	6.191	6.118	EPSD	COSMIC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	P53805	RCAN1	P49841	GSK3B	T247	P244L	244	Missense	distal	-3	no	6.145	6.271	EPSD	COSMIC	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	P53805	RCAN1	P49841	GSK3B	T247	R243K	243	Missense	distal	-4	no	6.145	6.467	EPSD	COSMIC;GDSC;CCLE	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	P53805	RCAN1	P49841	GSK3B	T247	T247M	247	Missense	central	0	yes	6.145	0.000	EPSD	COSMIC;GDSC;CCLE	6.007	Loss
CMGC_GSK_GSK3B_ST	O15033	AREL1	P49841	GSK3B	T343	P344L	344	Missense	proximal	1	no	8.880	6.019	EPSD	COSMIC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	O15033	AREL1	P49841	GSK3B	T343	S337L	337	Missense	distal	-6	no	8.880	8.879	EPSD	COSMIC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	O15033	AREL1	P49841	GSK3B	T343	V347G	347	Missense	distal	4	no	8.880	8.027	EPSD	COSMIC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	O15033	AREL1	P49841	GSK3B	T343	T343P	343	Missense	central	0	yes	8.880	0.000	EPSD	COSMIC	6.007	Loss
CMGC_GSK_GSK3B_ST	O15033	AREL1	P49841	GSK3B	S358	V353A	353	Missense	distal	-5	no	7.688	7.386	EPSD	COSMIC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	P04198	MYCN	P49841	GSK3B	T58	P57H	57	Missense	proximal	-1	no	12.373	12.266	PhosphoSitePlus	COSMIC;GDSC;CCLE	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	P04198	MYCN	P49841	GSK3B	T58	S64G	64	Missense	distal	6	no	12.373	12.370	PhosphoSitePlus	COSMIC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	P04198	MYCN	P49841	GSK3B	T58	P60S	60	Missense	proximal	2	no	12.373	11.930	PhosphoSitePlus	COSMIC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	P04198	MYCN	P49841	GSK3B	T58	P63L	63	Missense	distal	5	no	12.373	11.093	PhosphoSitePlus	COSMIC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	P04198	MYCN	P49841	GSK3B	T58	P57S	57	Missense	proximal	-1	no	12.373	12.317	PhosphoSitePlus	COSMIC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	P04198	MYCN	P49841	GSK3B	T58	P60L	60	Missense	proximal	2	no	12.373	11.989	PhosphoSitePlus	COSMIC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	P04198	MYCN	P49841	GSK3B	T58	P59L	59	Missense	proximal	1	no	12.373	9.513	PhosphoSitePlus	COSMIC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	P04198	MYCN	P49841	GSK3B	T58	L55M	55	Missense	distal	-3	no	12.373	12.336	PhosphoSitePlus	COSMIC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	P04198	MYCN	P49841	GSK3B	T142	A143T	143	Missense	proximal	1	no	5.696	6.237	EPSD	COSMIC	6.007	Gain
CMGC_GSK_GSK3B_ST	P04198	MYCN	P49841	GSK3B	S145	A147T	147	Missense	proximal	2	no	7.823	7.942	EPSD	COSMIC	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	P04198	MYCN	P49841	GSK3B	S145	A152D	152	Missense	distal	7	no	7.823	7.530	EPSD	COSMIC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	P04198	MYCN	P49841	GSK3B	S145	P140L	140	Missense	distal	-5	no	7.823	8.089	EPSD	COSMIC	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	P04198	MYCN	P49841	GSK3B	S145	P141L	141	Missense	distal	-4	no	7.823	7.036	EPSD	COSMIC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	P04198	MYCN	P49841	GSK3B	S145	A143T	143	Missense	proximal	-2	no	7.823	8.185	EPSD	COSMIC	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	P04198	MYCN	P49841	GSK3B	S149	A147T	147	Missense	proximal	-2	no	6.871	7.233	EPSD	COSMIC	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	P04198	MYCN	P49841	GSK3B	S149	A152D	152	Missense	distal	3	no	6.871	7.303	EPSD	COSMIC	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	P04198	MYCN	P49841	GSK3B	S149	A143T	143	Missense	distal	-6	no	6.871	6.803	EPSD	COSMIC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	P04198	MYCN	P49841	GSK3B	S156	A152D	152	Missense	distal	-4	no	6.243	6.803	EPSD	COSMIC	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	P04198	MYCN	P49841	GSK3B	T259	T259I	259	Missense	central	0	yes	6.316	0.000	EPSD	COSMIC	6.007	Loss
CMGC_GSK_GSK3B_ST	P04198	MYCN	P49841	GSK3B	T259	S255A	255	Missense	distal	-4	no	6.316	5.156	EPSD	COSMIC	6.007	Loss
CMGC_GSK_GSK3B_ST	P04198	MYCN	P49841	GSK3B	T259	S253G	253	Missense	distal	-6	no	6.316	6.332	EPSD	COSMIC	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	P04198	MYCN	P49841	GSK3B	T259	D258N	258	Missense	proximal	-1	no	6.316	6.438	EPSD	COSMIC	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	P04198	MYCN	P49841	GSK3B	S261	D265N	265	Missense	distal	4	no	6.766	5.579	EPSD	COSMIC	6.007	Loss
CMGC_GSK_GSK3B_ST	P04198	MYCN	P49841	GSK3B	S261	T259I	259	Missense	proximal	-2	no	6.766	6.728	EPSD	COSMIC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	P04198	MYCN	P49841	GSK3B	S261	S255A	255	Missense	distal	-6	no	6.766	6.777	EPSD	COSMIC	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	P04198	MYCN	P49841	GSK3B	S261	D258N	258	Missense	distal	-3	no	6.766	6.625	EPSD	COSMIC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	P04198	MYCN	P49841	GSK3B	S261	D268H	268	Missense	distal	7	no	6.766	7.337	EPSD	COSMIC	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	P04198	MYCN	P49841	GSK3B	S287	S289P	289	Missense	proximal	2	no	5.933	6.376	EPSD	COSMIC	6.007	Gain
CMGC_GSK_GSK3B_ST	P04198	MYCN	P49841	GSK3B	S288	S289P	289	Missense	proximal	1	no	2.901	6.746	EPSD	COSMIC	6.007	Gain
CMGC_GSK_GSK3B_ST	P04198	MYCN	P49841	GSK3B	T291	S289P	289	Missense	proximal	-2	no	5.783	6.039	EPSD	COSMIC	6.007	Gain
CMGC_GSK_GSK3B_ST	P04198	MYCN	P49841	GSK3B	S355	K351Q	351	Missense	distal	-4	no	7.011	7.046	EPSD	COSMIC	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	P04198	MYCN	P49841	GSK3B	S355	K348E	348	Missense	distal	-7	no	7.011	7.022	EPSD	COSMIC	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	P04198	MYCN	P49841	GSK3B	S355	A354T	354	Missense	proximal	-1	no	7.011	7.090	EPSD	COSMIC	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	P04198	MYCN	P49841	GSK3B	S355	P356L	356	Missense	proximal	1	no	7.011	4.150	EPSD	COSMIC	6.007	Loss
CMGC_GSK_GSK3B_ST	P04198	MYCN	P49841	GSK3B	S371	P364S	364	Missense	distal	-7	no	9.672	9.674	EPSD	COSMIC	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	P04198	MYCN	P49841	GSK3B	S371	P365A	365	Missense	distal	-6	no	9.672	9.662	EPSD	COSMIC;GDSC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	P04198	MYCN	P49841	GSK3B	S371	E378K	378	Missense	distal	7	no	9.672	9.564	EPSD	COSMIC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	P04198	MYCN	P49841	GSK3B	S371	K366T	366	Missense	distal	-5	no	9.672	9.761	EPSD	COSMIC	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	P04198	MYCN	P49841	GSK3B	S371	E378G	378	Missense	distal	7	no	9.672	9.653	EPSD	COSMIC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	P04198	MYCN	P49841	GSK3B	S371	P365Q	365	Missense	distal	-6	no	9.672	9.647	EPSD	COSMIC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	P04198	MYCN	P49841	GSK3B	S371	L370S	370	Missense	proximal	-1	no	9.672	9.747	EPSD	COSMIC	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	P04198	MYCN	P49841	GSK3B	S371	P365S	365	Missense	distal	-6	no	9.672	9.652	EPSD	COSMIC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	P04198	MYCN	P49841	GSK3B	S371	R373L	373	Missense	proximal	2	no	9.672	9.714	EPSD	COSMIC	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	P04198	MYCN	P49841	GSK3B	S375	E378G	378	Missense	distal	3	no	5.954	6.018	EPSD	COSMIC	6.007	Gain
CMGC_GSK_GSK3B_ST	P98170	XIAP	P49841	GSK3B	T180	H178Q	178	Missense	proximal	-2	no	7.708	7.768	PhosphoSitePlus	COSMIC	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	P98170	XIAP	P49841	GSK3B	T359	R365G	365	Missense	distal	6	no	9.465	9.467	EPSD	COSMIC	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	P98170	XIAP	P49841	GSK3B	T359	V353A	353	Missense	distal	-6	no	9.465	9.543	EPSD	COSMIC	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	P98170	XIAP	P49841	GSK3B	S402	N403K	403	Missense	proximal	1	no	4.512	6.486	EPSD	COSMIC	6.007	Gain
CMGC_GSK_GSK3B_ST	P98170	XIAP	P49841	GSK3B	S430	T437I	437	Missense	distal	7	no	6.390	6.785	EPSD	COSMIC;GDSC;CCLE	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	P98170	XIAP	P49841	GSK3B	S430	Q432H	432	Missense	proximal	2	no	6.390	5.842	EPSD	COSMIC	6.007	Loss
CMGC_GSK_GSK3B_ST	P98170	XIAP	P49841	GSK3B	S430	S430L	430	Missense	central	0	yes	6.390	0.000	EPSD	COSMIC	6.007	Loss
CMGC_GSK_GSK3B_ST	P54132	BLM	P49841	GSK3B	T57	D64H	64	Missense	distal	7	no	5.829	6.401	EPSD	COSMIC	6.007	Gain
CMGC_GSK_GSK3B_ST	P54132	BLM	P49841	GSK3B	T114	F111V	111	Missense	distal	-3	no	6.548	6.648	EPSD	COSMIC	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	P54132	BLM	P49841	GSK3B	T114	P109L	109	Missense	distal	-5	no	6.548	6.813	EPSD	COSMIC	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	P54132	BLM	P49841	GSK3B	T114	P109S	109	Missense	distal	-5	no	6.548	6.704	EPSD	COSMIC	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	P54132	BLM	P49841	GSK3B	T114	V118I	118	Missense	distal	4	no	6.548	5.616	EPSD	COSMIC	6.007	Loss
CMGC_GSK_GSK3B_ST	P54132	BLM	P49841	GSK3B	T114	D110Y	110	Missense	distal	-4	no	6.548	6.348	EPSD	COSMIC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	P54132	BLM	P49841	GSK3B	T114	P115L	115	Missense	proximal	1	no	6.548	3.687	EPSD	COSMIC	6.007	Loss
CMGC_GSK_GSK3B_ST	P54132	BLM	P49841	GSK3B	T114	E117K	117	Missense	distal	3	no	6.548	6.440	EPSD	COSMIC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	P54132	BLM	P49841	GSK3B	T121	V118I	118	Missense	distal	-3	no	7.252	7.199	EPSD	COSMIC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	P54132	BLM	P49841	GSK3B	T121	P126S	126	Missense	distal	5	no	7.252	6.298	EPSD	COSMIC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	P54132	BLM	P49841	GSK3B	T121	P115L	115	Missense	distal	-6	no	7.252	7.230	EPSD	COSMIC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	P54132	BLM	P49841	GSK3B	T121	E117K	117	Missense	distal	-4	no	7.252	6.985	EPSD	COSMIC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	P54132	BLM	P49841	GSK3B	T122	P126S	126	Missense	distal	4	no	3.742	6.713	EPSD	COSMIC	6.007	Gain
CMGC_GSK_GSK3B_ST	P54132	BLM	P49841	GSK3B	S131	P126S	126	Missense	distal	-5	no	5.966	6.123	EPSD	COSMIC	6.007	Gain
CMGC_GSK_GSK3B_ST	P54132	BLM	P49841	GSK3B	S144	S147F	147	Missense	distal	3	no	7.561	7.350	EPSD	COSMIC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	P54132	BLM	P49841	GSK3B	S144	S144L	144	Missense	central	0	yes	7.561	0.000	EPSD	COSMIC	6.007	Loss
CMGC_GSK_GSK3B_ST	P54132	BLM	P49841	GSK3B	S144	T150I	150	Missense	distal	6	no	7.561	7.558	EPSD	COSMIC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	P54132	BLM	P49841	GSK3B	S144	I151M	151	Missense	distal	7	no	7.561	7.594	EPSD	COSMIC	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	P54132	BLM	P49841	GSK3B	T171	E164K	164	Missense	distal	-7	no	8.317	8.306	PhosphoSitePlus	COSMIC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	P54132	BLM	P49841	GSK3B	T171	S168L	168	Missense	distal	-3	no	8.317	8.326	PhosphoSitePlus	COSMIC	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	P54132	BLM	P49841	GSK3B	T171	H176D	176	Missense	distal	5	no	8.317	9.096	PhosphoSitePlus	COSMIC	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	P54132	BLM	P49841	GSK3B	S304	P305S	305	Missense	proximal	1	no	7.653	3.808	EPSD	COSMIC	6.007	Loss
CMGC_GSK_GSK3B_ST	P54132	BLM	P49841	GSK3B	S312	P305S	305	Missense	distal	-7	no	6.066	6.068	EPSD	COSMIC	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	P54132	BLM	P49841	GSK3B	S312	S315Y	315	Missense	distal	3	no	6.066	5.644	EPSD	COSMIC	6.007	Loss
CMGC_GSK_GSK3B_ST	P54132	BLM	P49841	GSK3B	S312	C318S	318	Missense	distal	6	no	6.066	6.079	EPSD	COSMIC;GDSC;CCLE	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	P54132	BLM	P49841	GSK3B	S316	S315Y	315	Missense	proximal	-1	no	6.978	6.838	EPSD	COSMIC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	P54132	BLM	P49841	GSK3B	S316	C318S	318	Missense	proximal	2	no	6.978	7.470	EPSD	COSMIC;GDSC;CCLE	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	P54132	BLM	P49841	GSK3B	T359	A363S	363	Missense	distal	4	no	3.947	6.359	EPSD	COSMIC	6.007	Gain
CMGC_GSK_GSK3B_ST	P54132	BLM	P49841	GSK3B	S422	S426L	426	Missense	distal	4	no	6.516	3.798	EPSD	COSMIC	6.007	Loss
CMGC_GSK_GSK3B_ST	P54132	BLM	P49841	GSK3B	S422	N417S	417	Missense	distal	-5	no	6.516	6.808	EPSD	COSMIC	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	P54132	BLM	P49841	GSK3B	S422	D415Y	415	Missense	distal	-7	no	6.516	6.541	EPSD	COSMIC	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	P54132	BLM	P49841	GSK3B	T508	G512E	512	Missense	distal	4	no	5.092	6.314	EPSD	COSMIC	6.007	Gain
CMGC_GSK_GSK3B_ST	P54132	BLM	P49841	GSK3B	S579	S580P	580	Missense	proximal	1	no	2.381	6.226	EPSD	COSMIC	6.007	Gain
CMGC_GSK_GSK3B_ST	P54132	BLM	P49841	GSK3B	S601	D606N	606	Missense	distal	5	no	6.085	5.658	EPSD	COSMIC	6.007	Loss
CMGC_GSK_GSK3B_ST	P54132	BLM	P49841	GSK3B	S601	R599K	599	Missense	proximal	-2	no	6.085	6.066	EPSD	COSMIC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	P54132	BLM	P49841	GSK3B	S706	S706F	706	Missense	central	0	yes	7.890	0.000	EPSD	COSMIC	6.007	Loss
CMGC_GSK_GSK3B_ST	P54132	BLM	P49841	GSK3B	S714	V721I	721	Missense	distal	7	no	11.395	11.305	EPSD	COSMIC;GDSC;CCLE	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	P54132	BLM	P49841	GSK3B	S729	P733S	733	Missense	distal	4	no	4.251	7.222	EPSD	COSMIC	6.007	Gain
CMGC_GSK_GSK3B_ST	P54132	BLM	P49841	GSK3B	S1138	G1134C	1134	Missense	distal	-4	no	6.050	4.364	EPSD	COSMIC	6.007	Loss
CMGC_GSK_GSK3B_ST	P54132	BLM	P49841	GSK3B	S1138	N1141S	1141	Missense	distal	3	no	6.050	6.002	EPSD	COSMIC;GDSC;CCLE	6.007	Loss
CMGC_GSK_GSK3B_ST	P54132	BLM	P49841	GSK3B	S1138	R1139Q	1139	Missense	proximal	1	no	6.050	5.102	EPSD	COSMIC;CCLE	6.007	Loss
CMGC_GSK_GSK3B_ST	P54132	BLM	P49841	GSK3B	S1138	H1140Q	1140	Missense	proximal	2	no	6.050	6.598	EPSD	COSMIC	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	P54132	BLM	P49841	GSK3B	S1286	Q1283H	1283	Missense	distal	-3	no	6.378	6.460	EPSD	COSMIC	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	P54132	BLM	P49841	GSK3B	S1286	S1290L	1290	Missense	distal	4	no	6.378	3.660	EPSD	COSMIC	6.007	Loss
CMGC_GSK_GSK3B_ST	P54132	BLM	P49841	GSK3B	S1290	Q1283H	1283	Missense	distal	-7	no	9.665	9.668	EPSD	COSMIC	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	P54132	BLM	P49841	GSK3B	S1290	S1290L	1290	Missense	central	0	yes	9.665	0.000	EPSD	COSMIC	6.007	Loss
CMGC_GSK_GSK3B_ST	P54132	BLM	P49841	GSK3B	S1296	S1302F	1302	Missense	distal	6	no	7.903	7.891	EPSD	COSMIC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	P54132	BLM	P49841	GSK3B	S1296	S1290L	1290	Missense	distal	-6	no	7.903	7.902	EPSD	COSMIC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	P54132	BLM	P49841	GSK3B	S1300	S1302F	1302	Missense	proximal	2	no	9.897	9.553	EPSD	COSMIC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	P54132	BLM	P49841	GSK3B	S1375	S1380R	1380	Missense	distal	5	no	5.916	6.232	EPSD	COSMIC	6.007	Gain
CMGC_GSK_GSK3B_ST	P54132	BLM	P49841	GSK3B	S1379	S1373F	1373	Missense	distal	-6	no	6.324	6.271	EPSD	COSMIC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	P54132	BLM	P49841	GSK3B	S1379	S1380R	1380	Missense	proximal	1	no	6.324	7.849	EPSD	COSMIC	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	P54132	BLM	P49841	GSK3B	S1379	A1382T	1382	Missense	distal	3	no	6.324	6.628	EPSD	COSMIC	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	P54132	BLM	P49841	GSK3B	S1390	K1395I	1395	Missense	distal	5	no	6.067	5.959	EPSD	COSMIC	6.007	Loss
CMGC_GSK_GSK3B_ST	E9PAV3	NACA	P49841	GSK3B	S271	A274V	274	Missense	distal	3	no	7.492	7.620	EPSD	COSMIC	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	E9PAV3	NACA	P49841	GSK3B	S271	K267R	267	Missense	distal	-4	no	7.492	7.169	EPSD	COSMIC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	E9PAV3	NACA	P49841	GSK3B	S506	S506F	506	Missense	central	0	yes	6.061	0.000	EPSD	COSMIC	6.007	Loss
CMGC_GSK_GSK3B_ST	E9PAV3	NACA	P49841	GSK3B	S575	S570F	570	Missense	distal	-5	no	7.239	7.799	EPSD	COSMIC	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	E9PAV3	NACA	P49841	GSK3B	S575	P580A	580	Missense	distal	5	no	7.239	6.210	EPSD	COSMIC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	E9PAV3	NACA	P49841	GSK3B	S579	P580A	580	Missense	proximal	1	no	6.972	3.239	EPSD	COSMIC	6.007	Loss
CMGC_GSK_GSK3B_ST	E9PAV3	NACA	P49841	GSK3B	S585	P580A	580	Missense	distal	-5	no	9.009	9.443	EPSD	COSMIC	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	E9PAV3	NACA	P49841	GSK3B	T744	P740S	740	Missense	distal	-4	no	8.254	8.818	EPSD	COSMIC	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	E9PAV3	NACA	P49841	GSK3B	S802	P796L	796	Missense	distal	-6	no	7.901	7.879	EPSD	COSMIC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	E9PAV3	NACA	P49841	GSK3B	S802	R807Q	807	Missense	distal	5	no	7.901	7.563	EPSD	COSMIC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	E9PAV3	NACA	P49841	GSK3B	S874	T871P	871	Missense	distal	-3	no	7.231	7.089	EPSD	COSMIC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	E9PAV3	NACA	P49841	GSK3B	S917	A921V	921	Missense	distal	4	no	7.255	7.277	EPSD	COSMIC;CCLE	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	E9PAV3	NACA	P49841	GSK3B	T941	P948L	948	Missense	distal	7	no	6.638	6.687	EPSD	COSMIC	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	E9PAV3	NACA	P49841	GSK3B	T946	P948L	948	Missense	proximal	2	no	6.385	6.001	EPSD	COSMIC	6.007	Loss
CMGC_GSK_GSK3B_ST	E9PAV3	NACA	P49841	GSK3B	S949	P948L	948	Missense	proximal	-1	no	6.462	6.331	EPSD	COSMIC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	E9PAV3	NACA	P49841	GSK3B	T987	P982L	982	Missense	distal	-5	no	6.921	7.187	EPSD	COSMIC	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	E9PAV3	NACA	P49841	GSK3B	T987	A991V	991	Missense	distal	4	no	6.921	6.943	EPSD	COSMIC;CCLE	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	E9PAV3	NACA	P49841	GSK3B	T992	G999S	999	Missense	distal	7	no	6.254	6.234	EPSD	COSMIC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	E9PAV3	NACA	P49841	GSK3B	T992	A991V	991	Missense	proximal	-1	no	6.254	6.457	EPSD	COSMIC;CCLE	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	E9PAV3	NACA	P49841	GSK3B	S995	G999S	999	Missense	distal	4	no	6.854	10.097	EPSD	COSMIC	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	E9PAV3	NACA	P49841	GSK3B	S995	A991V	991	Missense	distal	-4	no	6.854	6.780	EPSD	COSMIC;CCLE	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	E9PAV3	NACA	P49841	GSK3B	T1010	V1014A	1014	Missense	distal	4	no	6.850	6.828	EPSD	COSMIC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	E9PAV3	NACA	P49841	GSK3B	T1010	T1010P	1010	Missense	central	0	yes	6.850	0.000	EPSD	COSMIC	6.007	Loss
CMGC_GSK_GSK3B_ST	E9PAV3	NACA	P49841	GSK3B	T1010	A1008V	1008	Missense	proximal	-2	no	6.850	7.152	EPSD	COSMIC	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	E9PAV3	NACA	P49841	GSK3B	T1010	P1012L	1012	Missense	proximal	2	no	6.850	6.466	EPSD	COSMIC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	E9PAV3	NACA	P49841	GSK3B	T1010	A1008D	1008	Missense	proximal	-2	no	6.850	7.169	EPSD	COSMIC;CCLE	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	E9PAV3	NACA	P49841	GSK3B	T1015	S1022G	1022	Missense	distal	7	no	6.160	6.179	EPSD	COSMIC	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	E9PAV3	NACA	P49841	GSK3B	T1015	V1014A	1014	Missense	proximal	-1	no	6.160	5.957	EPSD	COSMIC	6.007	Loss
CMGC_GSK_GSK3B_ST	E9PAV3	NACA	P49841	GSK3B	T1015	T1010P	1010	Missense	distal	-5	no	6.160	5.714	EPSD	COSMIC	6.007	Loss
CMGC_GSK_GSK3B_ST	E9PAV3	NACA	P49841	GSK3B	T1015	A1008V	1008	Missense	distal	-7	no	6.160	6.159	EPSD	COSMIC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	E9PAV3	NACA	P49841	GSK3B	T1015	P1012L	1012	Missense	distal	-3	no	6.160	6.286	EPSD	COSMIC	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	E9PAV3	NACA	P49841	GSK3B	T1015	A1008D	1008	Missense	distal	-7	no	6.160	6.140	EPSD	COSMIC;CCLE	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	E9PAV3	NACA	P49841	GSK3B	S1018	S1022G	1022	Missense	distal	4	no	10.603	7.360	EPSD	COSMIC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	E9PAV3	NACA	P49841	GSK3B	S1018	V1014A	1014	Missense	distal	-4	no	10.603	10.677	EPSD	COSMIC	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	E9PAV3	NACA	P49841	GSK3B	S1018	P1012L	1012	Missense	distal	-6	no	10.603	10.581	EPSD	COSMIC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	E9PAV3	NACA	P49841	GSK3B	S1022	S1022G	1022	Missense	central	0	yes	8.912	0.000	EPSD	COSMIC	6.007	Loss
CMGC_GSK_GSK3B_ST	E9PAV3	NACA	P49841	GSK3B	S1022	P1029T	1029	Missense	distal	7	no	8.912	8.916	EPSD	COSMIC	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	E9PAV3	NACA	P49841	GSK3B	T1050	P1057S	1057	Missense	distal	7	no	6.914	6.977	EPSD	COSMIC	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	E9PAV3	NACA	P49841	GSK3B	T1059	P1057S	1057	Missense	proximal	-2	no	7.536	7.280	EPSD	COSMIC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	E9PAV3	NACA	P49841	GSK3B	S1089	G1093D	1093	Missense	distal	4	no	6.241	7.061	EPSD	COSMIC	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	E9PAV3	NACA	P49841	GSK3B	T1109	M1104I	1104	Missense	distal	-5	no	6.082	6.252	EPSD	COSMIC	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	E9PAV3	NACA	P49841	GSK3B	T1128	P1134S	1134	Missense	distal	6	no	8.774	8.771	EPSD	COSMIC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	E9PAV3	NACA	P49841	GSK3B	T1132	P1134S	1134	Missense	proximal	2	no	6.326	5.882	EPSD	COSMIC	6.007	Loss
CMGC_GSK_GSK3B_ST	E9PAV3	NACA	P49841	GSK3B	T1174	T1173A	1173	Missense	proximal	-1	no	8.864	8.784	EPSD	COSMIC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	E9PAV3	NACA	P49841	GSK3B	T1174	S1181F	1181	Missense	distal	7	no	8.864	8.941	EPSD	COSMIC	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	E9PAV3	NACA	P49841	GSK3B	T1178	T1173A	1173	Missense	distal	-5	no	6.385	6.374	EPSD	COSMIC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	E9PAV3	NACA	P49841	GSK3B	T1178	S1181F	1181	Missense	distal	3	no	6.385	6.175	EPSD	COSMIC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	E9PAV3	NACA	P49841	GSK3B	T1197	A1199S	1199	Missense	proximal	2	no	8.865	8.858	EPSD	COSMIC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	E9PAV3	NACA	P49841	GSK3B	T1201	A1199S	1199	Missense	proximal	-2	no	6.380	6.715	EPSD	COSMIC	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	E9PAV3	NACA	P49841	GSK3B	T1201	P1205L	1205	Missense	distal	4	no	6.380	6.633	EPSD	COSMIC	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	E9PAV3	NACA	P49841	GSK3B	S1213	P1214H	1214	Missense	proximal	1	no	7.192	3.492	EPSD	COSMIC	6.007	Loss
CMGC_GSK_GSK3B_ST	E9PAV3	NACA	P49841	GSK3B	T1220	P1214H	1214	Missense	distal	-6	no	8.880	8.826	EPSD	COSMIC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	E9PAV3	NACA	P49841	GSK3B	S1236	T1243P	1243	Missense	distal	7	no	7.257	7.252	EPSD	COSMIC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	E9PAV3	NACA	P49841	GSK3B	T1242	T1243P	1243	Missense	proximal	1	no	3.460	6.651	EPSD	COSMIC	6.007	Gain
CMGC_GSK_GSK3B_ST	E9PAV3	NACA	P49841	GSK3B	T1243	A1246E	1246	Missense	distal	3	no	8.899	9.217	EPSD	COSMIC	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	E9PAV3	NACA	P49841	GSK3B	T1243	T1243P	1243	Missense	central	0	yes	8.899	0.000	EPSD	COSMIC	6.007	Loss
CMGC_GSK_GSK3B_ST	E9PAV3	NACA	P49841	GSK3B	T1247	P1251L	1251	Missense	distal	4	no	6.704	6.958	EPSD	COSMIC	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	E9PAV3	NACA	P49841	GSK3B	T1247	A1246E	1246	Missense	proximal	-1	no	6.704	6.847	EPSD	COSMIC	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	E9PAV3	NACA	P49841	GSK3B	T1247	T1243P	1243	Missense	distal	-4	no	6.704	6.476	EPSD	COSMIC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	E9PAV3	NACA	P49841	GSK3B	T1247	G1254S	1254	Missense	distal	7	no	6.704	6.685	EPSD	COSMIC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	E9PAV3	NACA	P49841	GSK3B	S1250	P1255L	1255	Missense	distal	5	no	6.698	5.417	EPSD	COSMIC	6.007	Loss
CMGC_GSK_GSK3B_ST	E9PAV3	NACA	P49841	GSK3B	S1250	P1251L	1251	Missense	proximal	1	no	6.698	3.837	EPSD	COSMIC	6.007	Loss
CMGC_GSK_GSK3B_ST	E9PAV3	NACA	P49841	GSK3B	S1250	A1246E	1246	Missense	distal	-4	no	6.698	7.260	EPSD	COSMIC	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	E9PAV3	NACA	P49841	GSK3B	S1250	T1243P	1243	Missense	distal	-7	no	6.698	6.669	EPSD	COSMIC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	E9PAV3	NACA	P49841	GSK3B	S1250	G1254S	1254	Missense	distal	4	no	6.698	9.941	EPSD	COSMIC	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	E9PAV3	NACA	P49841	GSK3B	S1250	A1256G	1256	Missense	distal	6	no	6.698	6.696	EPSD	COSMIC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	E9PAV3	NACA	P49841	GSK3B	T1257	P1255L	1255	Missense	proximal	-2	no	6.481	6.151	EPSD	COSMIC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	E9PAV3	NACA	P49841	GSK3B	T1257	P1251L	1251	Missense	distal	-6	no	6.481	6.459	EPSD	COSMIC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	E9PAV3	NACA	P49841	GSK3B	T1257	P1259S	1259	Missense	proximal	2	no	6.481	6.037	EPSD	COSMIC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	E9PAV3	NACA	P49841	GSK3B	T1257	G1254S	1254	Missense	distal	-3	no	6.481	6.485	EPSD	COSMIC	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	E9PAV3	NACA	P49841	GSK3B	T1257	P1264L	1264	Missense	distal	7	no	6.481	6.530	EPSD	COSMIC	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	E9PAV3	NACA	P49841	GSK3B	T1257	A1256G	1256	Missense	proximal	-1	no	6.481	6.643	EPSD	COSMIC	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	E9PAV3	NACA	P49841	GSK3B	T1257	P1258S	1258	Missense	proximal	1	no	6.481	2.637	EPSD	COSMIC	6.007	Loss
CMGC_GSK_GSK3B_ST	E9PAV3	NACA	P49841	GSK3B	T1265	P1259S	1259	Missense	distal	-6	no	6.791	6.770	EPSD	COSMIC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	E9PAV3	NACA	P49841	GSK3B	T1265	P1264L	1264	Missense	proximal	-1	no	6.791	6.659	EPSD	COSMIC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	E9PAV3	NACA	P49841	GSK3B	T1265	P1258S	1258	Missense	distal	-7	no	6.791	6.792	EPSD	COSMIC	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	E9PAV3	NACA	P49841	GSK3B	T1293	P1289L	1289	Missense	distal	-4	no	6.518	5.732	EPSD	COSMIC	6.007	Loss
CMGC_GSK_GSK3B_ST	E9PAV3	NACA	P49841	GSK3B	T1293	S1296F	1296	Missense	distal	3	no	6.518	6.308	EPSD	COSMIC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	E9PAV3	NACA	P49841	GSK3B	S1296	P1289L	1289	Missense	distal	-7	no	6.395	6.397	EPSD	COSMIC	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	E9PAV3	NACA	P49841	GSK3B	S1296	S1296F	1296	Missense	central	0	yes	6.395	0.000	EPSD	COSMIC	6.007	Loss
CMGC_GSK_GSK3B_ST	E9PAV3	NACA	P49841	GSK3B	S1342	G1345E	1345	Missense	distal	3	no	8.618	8.555	EPSD	COSMIC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	E9PAV3	NACA	P49841	GSK3B	S1474	P1472T	1472	Missense	proximal	-2	no	6.876	6.646	EPSD	COSMIC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	E9PAV3	NACA	P49841	GSK3B	S1512	T1519I	1519	Missense	distal	7	no	7.157	7.551	EPSD	COSMIC	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	E9PAV3	NACA	P49841	GSK3B	T1519	T1519I	1519	Missense	central	0	yes	6.113	0.000	EPSD	COSMIC	6.007	Loss
CMGC_GSK_GSK3B_ST	E9PAV3	NACA	P49841	GSK3B	T1519	P1526L	1526	Missense	distal	7	no	6.113	6.162	EPSD	COSMIC	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	E9PAV3	NACA	P49841	GSK3B	S1557	P1550L	1550	Missense	distal	-7	no	8.657	8.659	EPSD	COSMIC	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	E9PAV3	NACA	P49841	GSK3B	S1581	S1576Y	1576	Missense	distal	-5	no	6.073	6.725	EPSD	COSMIC	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	E9PAV3	NACA	P49841	GSK3B	T1615	P1617S	1617	Missense	proximal	2	no	6.387	5.943	EPSD	COSMIC	6.007	Loss
CMGC_GSK_GSK3B_ST	E9PAV3	NACA	P49841	GSK3B	T1615	A1618T	1618	Missense	distal	3	no	6.387	6.691	EPSD	COSMIC	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	E9PAV3	NACA	P49841	GSK3B	T1620	P1617S	1617	Missense	distal	-3	no	7.542	7.659	EPSD	COSMIC	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	E9PAV3	NACA	P49841	GSK3B	T1620	A1618T	1618	Missense	proximal	-2	no	7.542	7.904	EPSD	COSMIC	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	E9PAV3	NACA	P49841	GSK3B	S1623	P1617S	1617	Missense	distal	-6	no	7.454	7.433	EPSD	COSMIC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	E9PAV3	NACA	P49841	GSK3B	S1623	A1618T	1618	Missense	distal	-5	no	7.454	7.466	EPSD	COSMIC	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	E9PAV3	NACA	P49841	GSK3B	S1799	P1796S	1796	Missense	distal	-3	no	5.903	6.019	EPSD	COSMIC	6.007	Gain
CMGC_GSK_GSK3B_ST	E9PAV3	NACA	P49841	GSK3B	S1805	P1808L	1808	Missense	distal	3	no	7.237	6.919	EPSD	COSMIC;CCLE	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	E9PAV3	NACA	P49841	GSK3B	T1958	I1959L	1959	Missense	proximal	1	no	5.735	6.756	EPSD	COSMIC	6.007	Gain
CMGC_GSK_GSK3B_ST	E9PAV3	NACA	P49841	GSK3B	T1958	I1959V	1959	Missense	proximal	1	no	5.735	6.626	EPSD	COSMIC	6.007	Gain
CMGC_GSK_GSK3B_ST	E9PAV3	NACA	P49841	GSK3B	S1977	Y1975C	1975	Missense	proximal	-2	no	7.757	7.765	EPSD	COSMIC	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	E9PAV3	NACA	P49841	GSK3B	T2022	N2015D	2015	Missense	distal	-7	no	7.378	7.375	PhosphoSitePlus	COSMIC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	E9PAV3	NACA	P49841	GSK3B	T2022	T2024P	2024	Missense	proximal	2	no	7.378	7.696	PhosphoSitePlus	COSMIC	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	E9PAV3	NACA	P49841	GSK3B	T2022	V2025I	2025	Missense	distal	3	no	7.378	7.165	PhosphoSitePlus	COSMIC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	E9PAV3	NACA	P49841	GSK3B	T2022	E2028D	2028	Missense	distal	6	no	7.378	7.376	PhosphoSitePlus	COSMIC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	Q92837	FRAT1	P49841	GSK3B	S188	S188F	188	Missense	central	0	yes	6.852	0.000	PhosphoSitePlus	COSMIC	6.007	Loss
CAMK_MAPKAPK_MK2_MAPKAPK3_ST	Q8N5C8	TAB3	Q16644	MAPKAPK3	S102	H100P	100	Missense	proximal	-2	no	0.011	0.010	EPSD	COSMIC	0.011	Loss
CAMK_MAPKAPK_MK2_MAPKAPK3_ST	Q8N5C8	TAB3	Q16644	MAPKAPK3	S102	S101I	101	Missense	proximal	-1	no	0.011	0.010	EPSD	COSMIC	0.011	Loss
CAMK_MAPKAPK_MK2_MAPKAPK3_ST	Q8N5C8	TAB3	Q16644	MAPKAPK3	S102	R96Q	96	Missense	distal	-6	no	0.011	0.010	EPSD	COSMIC	0.011	Loss
CAMK_MAPKAPK_MK2_MAPKAPK3_ST	Q8N5C8	TAB3	Q16644	MAPKAPK3	S102	G105V	105	Missense	distal	3	no	0.011	0.010	EPSD	COSMIC	0.011	Loss
CAMK_MAPKAPK_MK2_MAPKAPK3_ST	Q8N5C8	TAB3	Q16644	MAPKAPK3	S103	H100P	100	Missense	distal	-3	no	0.014	0.013	EPSD	COSMIC	0.011	Down-regulation
CAMK_MAPKAPK_MK2_MAPKAPK3_ST	Q8N5C8	TAB3	Q16644	MAPKAPK3	S103	S101I	101	Missense	proximal	-2	no	0.014	0.010	EPSD	COSMIC	0.011	Loss
CAMK_MAPKAPK_MK2_MAPKAPK3_ST	Q8N5C8	TAB3	Q16644	MAPKAPK3	S103	R96Q	96	Missense	distal	-7	no	0.014	0.015	EPSD	COSMIC	0.011	Up-regulation
CAMK_MAPKAPK_MK2_MAPKAPK3_ST	Q8N5C8	TAB3	Q16644	MAPKAPK3	S385	P386S	386	Missense	proximal	1	no	0.029	0.028	EPSD	COSMIC	0.011	Down-regulation
CAMK_MAPKAPK_MK2_MAPKAPK3_ST	Q8N5C8	TAB3	Q16644	MAPKAPK3	S385	S388T	388	Missense	distal	3	no	0.029	0.026	EPSD	COSMIC	0.011	Down-regulation
CAMK_MAPKAPK_MK2_MAPKAPK3_ST	Q8N5C8	TAB3	Q16644	MAPKAPK3	S411	S409A	409	Missense	proximal	-2	no	0.013	0.010	EPSD	COSMIC	0.011	Loss
CAMK_MAPKAPK_MK2_MAPKAPK3_ST	Q8N5C8	TAB3	Q16644	MAPKAPK3	S563	V562L	562	Missense	proximal	-1	no	0.021	0.022	EPSD	COSMIC	0.011	Up-regulation
CAMK_MAPKAPK_MK2_MAPKAPK3_ST	Q8N5C8	TAB3	Q16644	MAPKAPK3	S669	R674H	674	Missense	distal	5	no	0.021	0.020	EPSD	COSMIC	0.011	Down-regulation
CAMK_MAPKAPK_MK2_MAPKAPK3_ST	Q8N5C8	TAB3	Q16644	MAPKAPK3	S669	R674C	674	Missense	distal	5	no	0.021	0.020	EPSD	COSMIC	0.011	Down-regulation
CAMK_MAPKAPK_MK2_MAPKAPK3_ST	Q14457	BECN1	Q16644	MAPKAPK3	S414	T417N	417	Missense	distal	3	no	0.012	0.013	EPSD	COSMIC	0.011	Up-regulation
TK_Tec_BMX_Y	P11362	FGFR1	P51813	BMX	Y463	G459R	459	Missense	distal	-4	no	2.354	2.985	EPSD	COSMIC	2.549	Gain
TK_Tec_BMX_Y	P11362	FGFR1	P51813	BMX	Y463	M456V	456	Missense	distal	-7	no	2.354	2.816	EPSD	COSMIC	2.549	Gain
TK_Tec_BMX_Y	P11362	FGFR1	P51813	BMX	Y653	K655R	655	Missense	proximal	2	no	4.661	4.682	EPSD;PhosphoSitePlus	COSMIC	2.549	Up-regulation
TK_Tec_BMX_Y	P11362	FGFR1	P51813	BMX	Y653	K655E	655	Missense	proximal	2	no	4.661	4.710	EPSD;PhosphoSitePlus	COSMIC	2.549	Up-regulation
TK_Tec_BMX_Y	P11362	FGFR1	P51813	BMX	Y653	K656E	656	Missense	distal	3	no	4.661	4.888	EPSD;PhosphoSitePlus	COSMIC	2.549	Up-regulation
TK_Tec_BMX_Y	P11362	FGFR1	P51813	BMX	Y653	K656M	656	Missense	distal	3	no	4.661	4.398	EPSD;PhosphoSitePlus	COSMIC	2.549	Down-regulation
TK_Tec_BMX_Y	P11362	FGFR1	P51813	BMX	Y653	K656N	656	Missense	distal	3	no	4.661	4.737	EPSD;PhosphoSitePlus	COSMIC	2.549	Up-regulation
TK_Tec_BMX_Y	P11362	FGFR1	P51813	BMX	Y653	R646W	646	Missense	distal	-7	no	4.661	3.774	EPSD;PhosphoSitePlus	COSMIC	2.549	Down-regulation
TK_Tec_BMX_Y	P11362	FGFR1	P51813	BMX	Y653	D647N	647	Missense	distal	-6	no	4.661	4.647	EPSD;PhosphoSitePlus	COSMIC	2.549	Down-regulation
TK_Tec_BMX_Y	P11362	FGFR1	P51813	BMX	Y653	D652G	652	Missense	proximal	-1	no	4.661	4.667	EPSD;PhosphoSitePlus	COSMIC	2.549	Up-regulation
TK_Tec_BMX_Y	P11362	FGFR1	P51813	BMX	Y653	G660S	660	Missense	distal	7	no	4.661	4.651	EPSD;PhosphoSitePlus	COSMIC	2.549	Down-regulation
TK_Tec_BMX_Y	P11362	FGFR1	P51813	BMX	Y653	R646Q	646	Missense	distal	-7	no	4.661	4.619	EPSD;PhosphoSitePlus	COSMIC	2.549	Down-regulation
TK_Tec_BMX_Y	P11362	FGFR1	P51813	BMX	Y653	I651T	651	Missense	proximal	-2	no	4.661	5.032	EPSD;PhosphoSitePlus	COSMIC	2.549	Up-regulation
TK_Tec_BMX_Y	P11362	FGFR1	P51813	BMX	Y653	K655I	655	Missense	proximal	2	no	4.661	4.601	EPSD;PhosphoSitePlus	COSMIC	2.549	Down-regulation
TK_Tec_BMX_Y	P11362	FGFR1	P51813	BMX	Y653	D652N	652	Missense	proximal	-1	no	4.661	4.641	EPSD;PhosphoSitePlus	COSMIC	2.549	Down-regulation
TK_Tec_BMX_Y	P11362	FGFR1	P51813	BMX	Y653	H649Y	649	Missense	distal	-4	no	4.661	3.996	EPSD;PhosphoSitePlus	COSMIC	2.549	Down-regulation
TK_Tec_BMX_Y	P11362	FGFR1	P51813	BMX	Y654	K655R	655	Missense	proximal	1	no	4.934	4.871	PhosphoSitePlus;EPSD	COSMIC	2.549	Down-regulation
TK_Tec_BMX_Y	P11362	FGFR1	P51813	BMX	Y654	K655E	655	Missense	proximal	1	no	4.934	4.916	PhosphoSitePlus;EPSD	COSMIC	2.549	Down-regulation
TK_Tec_BMX_Y	P11362	FGFR1	P51813	BMX	Y654	K656E	656	Missense	proximal	2	no	4.934	4.983	PhosphoSitePlus;EPSD	COSMIC	2.549	Up-regulation
TK_Tec_BMX_Y	P11362	FGFR1	P51813	BMX	Y654	K656M	656	Missense	proximal	2	no	4.934	4.852	PhosphoSitePlus;EPSD	COSMIC	2.549	Down-regulation
TK_Tec_BMX_Y	P11362	FGFR1	P51813	BMX	Y654	K656N	656	Missense	proximal	2	no	4.934	4.920	PhosphoSitePlus;EPSD	COSMIC	2.549	Down-regulation
TK_Tec_BMX_Y	P11362	FGFR1	P51813	BMX	Y654	D647N	647	Missense	distal	-7	no	4.934	5.406	PhosphoSitePlus;EPSD	COSMIC	2.549	Up-regulation
TK_Tec_BMX_Y	P11362	FGFR1	P51813	BMX	Y654	D652G	652	Missense	proximal	-2	no	4.934	4.694	PhosphoSitePlus;EPSD	COSMIC	2.549	Down-regulation
TK_Tec_BMX_Y	P11362	FGFR1	P51813	BMX	Y654	G660S	660	Missense	distal	6	no	4.934	4.933	PhosphoSitePlus;EPSD	COSMIC	2.549	Down-regulation
TK_Tec_BMX_Y	P11362	FGFR1	P51813	BMX	Y654	I651T	651	Missense	distal	-3	no	4.934	4.920	PhosphoSitePlus;EPSD	COSMIC	2.549	Down-regulation
TK_Tec_BMX_Y	P11362	FGFR1	P51813	BMX	Y654	R661Q	661	Missense	distal	7	no	4.934	4.944	PhosphoSitePlus;EPSD	COSMIC	2.549	Up-regulation
TK_Tec_BMX_Y	P11362	FGFR1	P51813	BMX	Y654	K655I	655	Missense	proximal	1	no	4.934	4.755	PhosphoSitePlus;EPSD	COSMIC	2.549	Down-regulation
TK_Tec_BMX_Y	P11362	FGFR1	P51813	BMX	Y654	D652N	652	Missense	proximal	-2	no	4.934	5.349	PhosphoSitePlus;EPSD	COSMIC	2.549	Up-regulation
TK_Tec_BMX_Y	P11362	FGFR1	P51813	BMX	Y654	H649Y	649	Missense	distal	-5	no	4.934	4.899	PhosphoSitePlus;EPSD	COSMIC	2.549	Down-regulation
TK_Tec_BMX_Y	Q05397	PTK2	P51813	BMX	Y441	P447S	447	Missense	distal	6	no	5.381	5.378	EPSD;PhosphoSitePlus	COSMIC	2.549	Down-regulation
TK_Tec_BMX_Y	Q05397	PTK2	P51813	BMX	Y441	S443R	443	Missense	proximal	2	no	5.381	5.433	EPSD;PhosphoSitePlus	COSMIC	2.549	Up-regulation
TK_Tec_BMX_Y	Q05397	PTK2	P51813	BMX	Y441	Y441F	441	Missense	central	0	yes	5.381	0.000	EPSD;PhosphoSitePlus	COSMIC	2.549	Loss
TK_Tec_BMX_Y	Q05397	PTK2	P51813	BMX	Y576	R569L	569	Missense	distal	-7	no	5.368	4.668	EPSD;PhosphoSitePlus	COSMIC	2.549	Down-regulation
TK_Tec_BMX_Y	Q05397	PTK2	P51813	BMX	Y576	A579V	579	Missense	distal	3	no	5.368	5.376	EPSD;PhosphoSitePlus	COSMIC	2.549	Up-regulation
TK_Tec_BMX_Y	Q05397	PTK2	P51813	BMX	Y577	A579V	579	Missense	proximal	2	no	4.877	4.846	EPSD;PhosphoSitePlus	COSMIC	2.549	Down-regulation
TK_Tec_BMX_Y	Q05397	PTK2	P51813	BMX	Y742	S745Y	745	Missense	distal	3	no	4.849	4.487	EPSD;PhosphoSitePlus	COSMIC	2.549	Down-regulation
TK_Tec_BMX_Y	Q05397	PTK2	P51813	BMX	Y861	D868N	868	Missense	distal	7	no	4.819	4.766	EPSD;PhosphoSitePlus	COSMIC	2.549	Down-regulation
TK_Tec_BMX_Y	Q05397	PTK2	P51813	BMX	Y861	G865C	865	Missense	distal	4	no	4.819	4.611	EPSD;PhosphoSitePlus	COSMIC	2.549	Down-regulation
TK_Tec_BMX_Y	Q05397	PTK2	P51813	BMX	Y898	E900V	900	Missense	proximal	2	no	4.895	4.810	EPSD;PhosphoSitePlus	COSMIC	2.549	Down-regulation
TK_Tec_BMX_Y	Q05397	PTK2	P51813	BMX	Y925	G930C	930	Missense	distal	5	no	5.146	4.396	PhosphoSitePlus;EPSD	COSMIC	2.549	Down-regulation
TK_Tec_BMX_Y	Q05397	PTK2	P51813	BMX	Y925	D918G	918	Missense	distal	-7	no	5.146	4.940	PhosphoSitePlus;EPSD	COSMIC	2.549	Down-regulation
TK_Tec_BMX_Y	Q05397	PTK2	P51813	BMX	Y925	E926K	926	Missense	proximal	1	no	5.146	5.164	PhosphoSitePlus;EPSD	COSMIC	2.549	Up-regulation
TK_Tec_BMX_Y	Q05397	PTK2	P51813	BMX	Y925	Y925C	925	Missense	central	0	yes	5.146	0.000	PhosphoSitePlus;EPSD	COSMIC	2.549	Loss
TK_Tec_BMX_Y	Q05397	PTK2	P51813	BMX	Y925	R919L	919	Missense	distal	-6	no	5.146	5.197	PhosphoSitePlus;EPSD	COSMIC	2.549	Up-regulation
TK_Tec_BMX_Y	Q05397	PTK2	P51813	BMX	Y925	R919Q	919	Missense	distal	-6	no	5.146	5.200	PhosphoSitePlus;EPSD	COSMIC	2.549	Up-regulation
TK_Tec_BMX_Y	Q05397	PTK2	P51813	BMX	Y1007	M1001V	1001	Missense	distal	-6	no	4.951	5.123	EPSD;PhosphoSitePlus	COSMIC	2.549	Up-regulation
TK_Tec_BMX_Y	Q05397	PTK2	P51813	BMX	Y1007	L1003F	1003	Missense	distal	-4	no	4.951	4.722	EPSD;PhosphoSitePlus	COSMIC	2.549	Down-regulation
TK_Tec_BMX_Y	Q07912	TNK2	P51813	BMX	Y284	H289N	289	Missense	distal	5	no	2.441	3.084	EPSD	COSMIC	2.549	Gain
TK_Tec_BMX_Y	Q07912	TNK2	P51813	BMX	Y284	P278H	278	Missense	distal	-6	no	2.441	2.609	EPSD	COSMIC	2.549	Gain
TK_Tec_BMX_Y	Q07912	TNK2	P51813	BMX	Y859	Y859S	859	Missense	central	0	yes	4.766	0.000	EPSD;PhosphoSitePlus	COSMIC;CCLE	2.549	Loss
TK_Tec_BMX_Y	Q07912	TNK2	P51813	BMX	Y859	E864G	864	Missense	distal	5	no	4.766	4.157	EPSD;PhosphoSitePlus	COSMIC	2.549	Down-regulation
TK_Tec_BMX_Y	Q07912	TNK2	P51813	BMX	Y860	Y859S	859	Missense	proximal	-1	no	4.769	4.754	PhosphoSitePlus;EPSD	COSMIC;CCLE	2.549	Down-regulation
TK_Tec_BMX_Y	Q07912	TNK2	P51813	BMX	Y860	E864G	864	Missense	distal	4	no	4.769	4.299	PhosphoSitePlus;EPSD	COSMIC	2.549	Down-regulation
TK_Tec_BMX_Y	P56945	BCAR1	P51813	BMX	Y12	V6M	6	Missense	distal	-6	no	3.444	3.272	PhosphoSitePlus	COSMIC	2.549	Down-regulation
TK_Tec_BMX_Y	P56945	BCAR1	P51813	BMX	Y12	E17K	17	Missense	distal	5	no	3.444	3.548	PhosphoSitePlus	COSMIC	2.549	Up-regulation
TK_Tec_BMX_Y	P56945	BCAR1	P51813	BMX	Y12	P19Q	19	Missense	distal	7	no	3.444	3.392	PhosphoSitePlus	COSMIC	2.549	Down-regulation
TK_Tec_BMX_Y	P56945	BCAR1	P51813	BMX	Y12	E17V	17	Missense	distal	5	no	3.444	2.731	PhosphoSitePlus	COSMIC	2.549	Down-regulation
TK_Tec_BMX_Y	P56945	BCAR1	P51813	BMX	Y12	A10V	10	Missense	proximal	-2	no	3.444	3.287	PhosphoSitePlus	COSMIC	2.549	Down-regulation
TK_Tec_BMX_Y	P56945	BCAR1	P51813	BMX	Y12	A8V	8	Missense	distal	-4	no	3.444	2.902	PhosphoSitePlus	COSMIC	2.549	Down-regulation
TK_Tec_BMX_Y	P56945	BCAR1	P51813	BMX	Y262	Y267N	267	Missense	distal	5	no	2.210	2.610	EPSD	COSMIC	2.549	Gain
TK_Tec_BMX_Y	Q13153	PAK1	P51813	BMX	Y153	S155Y	155	Missense	proximal	2	no	4.782	4.750	PhosphoSitePlus	COSMIC	2.549	Down-regulation
TK_Tec_BMX_Y	Q13153	PAK1	P51813	BMX	Y153	E151K	151	Missense	proximal	-2	no	4.782	4.690	PhosphoSitePlus	COSMIC	2.549	Down-regulation
TK_Tec_BMX_Y	Q13153	PAK1	P51813	BMX	Y153	D152H	152	Missense	proximal	-1	no	4.782	4.767	PhosphoSitePlus	COSMIC	2.549	Down-regulation
TK_Tec_BMX_Y	Q96T51	RUFY1	P51813	BMX	Y389	G395C	395	Missense	distal	6	no	4.671	4.688	PhosphoSitePlus;EPSD	COSMIC	2.549	Up-regulation
TK_Tec_BMX_Y	Q96T51	RUFY1	P51813	BMX	Y389	E385K	385	Missense	distal	-4	no	4.671	4.455	PhosphoSitePlus;EPSD	COSMIC	2.549	Down-regulation
TK_Tec_BMX_Y	Q96T51	RUFY1	P51813	BMX	Y400	G395C	395	Missense	distal	-5	no	4.715	4.625	EPSD;PhosphoSitePlus	COSMIC	2.549	Down-regulation
TK_Tec_BMX_Y	Q96T51	RUFY1	P51813	BMX	Y400	Y400C	400	Missense	central	0	yes	4.715	0.000	EPSD;PhosphoSitePlus	COSMIC	2.549	Loss
TK_Tec_BMX_Y	Q96T51	RUFY1	P51813	BMX	Y400	D402G	402	Missense	proximal	2	no	4.715	4.706	EPSD;PhosphoSitePlus	COSMIC	2.549	Down-regulation
TK_Tec_BMX_Y	P08581	MET	P51813	BMX	Y1234	Y1235D	1235	Missense	proximal	1	no	2.603	2.620	EPSD	COSMIC	2.549	Up-regulation
TK_Tec_BMX_Y	P08581	MET	P51813	BMX	Y1234	Y1230S	1230	Missense	distal	-4	no	2.603	3.562	EPSD	COSMIC	2.549	Up-regulation
TK_Tec_BMX_Y	P08581	MET	P51813	BMX	Y1234	D1228N	1228	Missense	distal	-6	no	2.603	2.589	EPSD	COSMIC	2.549	Down-regulation
TK_Tec_BMX_Y	P08581	MET	P51813	BMX	Y1234	M1229L	1229	Missense	distal	-5	no	2.603	2.776	EPSD	COSMIC	2.549	Up-regulation
TK_Tec_BMX_Y	P08581	MET	P51813	BMX	Y1234	D1231N	1231	Missense	distal	-3	no	2.603	2.581	EPSD	COSMIC	2.549	Down-regulation
TK_Tec_BMX_Y	P08581	MET	P51813	BMX	Y1234	D1228V	1228	Missense	distal	-6	no	2.603	2.720	EPSD	COSMIC	2.549	Up-regulation
TK_Tec_BMX_Y	P08581	MET	P51813	BMX	Y1234	H1238R	1238	Missense	distal	4	no	2.603	2.760	EPSD	COSMIC	2.549	Up-regulation
TK_Tec_BMX_Y	P08581	MET	P51813	BMX	Y1234	M1229V	1229	Missense	distal	-5	no	2.603	2.927	EPSD	COSMIC	2.549	Up-regulation
TK_Tec_BMX_Y	P08581	MET	P51813	BMX	Y1235	G1242D	1242	Missense	distal	7	no	4.805	4.866	PhosphoSitePlus	COSMIC	2.549	Up-regulation
TK_Tec_BMX_Y	P08581	MET	P51813	BMX	Y1235	G1242A	1242	Missense	distal	7	no	4.805	4.782	PhosphoSitePlus	COSMIC	2.549	Down-regulation
TK_Tec_BMX_Y	P08581	MET	P51813	BMX	Y1235	Y1235D	1235	Missense	central	0	yes	4.805	0.000	PhosphoSitePlus	COSMIC	2.549	Loss
TK_Tec_BMX_Y	P08581	MET	P51813	BMX	Y1235	D1228N	1228	Missense	distal	-7	no	4.805	5.277	PhosphoSitePlus	COSMIC	2.549	Up-regulation
TK_Tec_BMX_Y	P08581	MET	P51813	BMX	Y1235	M1229L	1229	Missense	distal	-6	no	4.805	4.960	PhosphoSitePlus	COSMIC	2.549	Up-regulation
TK_Tec_BMX_Y	P08581	MET	P51813	BMX	Y1235	D1231N	1231	Missense	distal	-4	no	4.805	5.173	PhosphoSitePlus	COSMIC	2.549	Up-regulation
TK_Tec_BMX_Y	P08581	MET	P51813	BMX	Y1235	G1242C	1242	Missense	distal	7	no	4.805	4.892	PhosphoSitePlus	COSMIC	2.549	Up-regulation
TK_Tec_BMX_Y	P08581	MET	P51813	BMX	Y1235	D1228V	1228	Missense	distal	-7	no	4.805	4.704	PhosphoSitePlus	COSMIC	2.549	Down-regulation
TK_Tec_BMX_Y	P08581	MET	P51813	BMX	Y1235	H1238R	1238	Missense	distal	3	no	4.805	5.014	PhosphoSitePlus	COSMIC	2.549	Up-regulation
TK_Tec_BMX_Y	P08581	MET	P51813	BMX	Y1235	M1229V	1229	Missense	distal	-6	no	4.805	4.977	PhosphoSitePlus	COSMIC	2.549	Up-regulation
Other_PLK_PLK2_PLK2_ST	Q9HC77	CENPJ	Q9NYY3	PLK2	S131	F133S	133	Missense	proximal	2	no	14.944	14.770	EPSD	COSMIC	13.807	Down-regulation
Other_PLK_PLK2_PLK2_ST	Q9HC77	CENPJ	Q9NYY3	PLK2	S595	I600F	600	Missense	distal	5	no	21.652	21.365	EPSD;PhosphoSitePlus	COSMIC	13.807	Down-regulation
Other_PLK_PLK2_PLK2_ST	Q9HC77	CENPJ	Q9NYY3	PLK2	S663	L661F	661	Missense	proximal	-2	no	14.657	13.190	EPSD	COSMIC;GDSC;CCLE	13.807	Loss
Other_PLK_PLK2_PLK2_ST	Q9HC77	CENPJ	Q9NYY3	PLK2	S663	Q670R	670	Missense	distal	7	no	14.657	15.115	EPSD	COSMIC	13.807	Up-regulation
Other_PLK_PLK2_PLK2_ST	Q9HC77	CENPJ	Q9NYY3	PLK2	S683	S683F	683	Missense	central	0	yes	14.691	0.000	EPSD	COSMIC	13.807	Loss
Other_PLK_PLK2_PLK2_ST	Q9HC77	CENPJ	Q9NYY3	PLK2	S759	D762Y	762	Missense	distal	3	no	16.334	16.588	EPSD	COSMIC	13.807	Up-regulation
Other_PLK_PLK2_PLK2_ST	Q9HC77	CENPJ	Q9NYY3	PLK2	S759	D766N	766	Missense	distal	7	no	16.334	17.012	EPSD	COSMIC	13.807	Up-regulation
Other_PLK_PLK2_PLK2_ST	Q9HC77	CENPJ	Q9NYY3	PLK2	S759	L758F	758	Missense	proximal	-1	no	16.334	16.193	EPSD	COSMIC	13.807	Down-regulation
Other_PLK_PLK2_PLK2_ST	Q9HC77	CENPJ	Q9NYY3	PLK2	S1081	T1074I	1074	Missense	distal	-7	no	14.567	14.601	EPSD	COSMIC	13.807	Up-regulation
Other_PLK_PLK2_PLK2_ST	O15350	TP73	Q9NYY3	PLK2	S47	E40G	40	Missense	distal	-7	no	13.046	13.952	EPSD	COSMIC	13.807	Gain
Other_PLK_PLK2_PLK2_ST	O15350	TP73	Q9NYY3	PLK2	S47	S48L	48	Missense	proximal	1	no	13.046	13.888	EPSD	COSMIC	13.807	Gain
Other_PLK_PLK2_PLK2_ST	O15350	TP73	Q9NYY3	PLK2	S48	D50Y	50	Missense	proximal	2	no	17.945	18.114	PhosphoSitePlus	COSMIC;GDSC;CCLE	13.807	Up-regulation
Other_PLK_PLK2_PLK2_ST	O15350	TP73	Q9NYY3	PLK2	S48	E55K	55	Missense	distal	7	no	17.945	17.653	PhosphoSitePlus	COSMIC	13.807	Down-regulation
Other_PLK_PLK2_PLK2_ST	O15350	TP73	Q9NYY3	PLK2	S48	S48L	48	Missense	central	0	yes	17.945	0.000	PhosphoSitePlus	COSMIC	13.807	Loss
Other_PLK_PLK2_PLK2_ST	O15350	TP73	Q9NYY3	PLK2	S471	S468N	468	Missense	distal	-3	no	15.653	15.529	EPSD	COSMIC	13.807	Down-regulation
Other_PLK_PLK2_PLK2_ST	O15350	TP73	Q9NYY3	PLK2	S471	S474P	474	Missense	distal	3	no	15.653	15.672	EPSD	COSMIC	13.807	Up-regulation
Other_PLK_PLK2_PLK2_ST	O15350	TP73	Q9NYY3	PLK2	S471	G478R	478	Missense	distal	7	no	15.653	16.445	EPSD	COSMIC;CCLE	13.807	Up-regulation
Other_PLK_PLK2_PLK2_ST	O15350	TP73	Q9NYY3	PLK2	S471	G464S	464	Missense	distal	-7	no	15.653	14.776	EPSD	COSMIC	13.807	Down-regulation
Other_PLK_PLK2_PLK2_ST	P62258	YWHAE	Q9NYY3	PLK2	S59	R56G	56	Missense	distal	-3	no	13.765	15.910	EPSD	COSMIC	13.807	Gain
Other_PLK_PLK2_PLK2_ST	P62258	YWHAE	Q9NYY3	PLK2	S148	A145V	145	Missense	distal	-3	no	15.332	13.462	EPSD	COSMIC	13.807	Loss
Other_PLK_PLK2_PLK2_ST	P62258	YWHAE	Q9NYY3	PLK2	S148	L149R	149	Missense	proximal	1	no	15.332	13.449	EPSD	COSMIC	13.807	Loss
Other_PLK_PLK2_PLK2_ST	P62258	YWHAE	Q9NYY3	PLK2	T208	T208M	208	Missense	central	0	yes	18.895	0.000	PhosphoSitePlus	COSMIC	13.807	Loss
Other_PLK_PLK2_PLK2_ST	P62258	YWHAE	Q9NYY3	PLK2	T208	I203V	203	Missense	distal	-5	no	18.895	18.606	PhosphoSitePlus	COSMIC	13.807	Down-regulation
Other_PLK_PLK2_PLK2_ST	P62258	YWHAE	Q9NYY3	PLK2	T208	A204T	204	Missense	distal	-4	no	18.895	18.458	PhosphoSitePlus	COSMIC	13.807	Down-regulation
Other_PLK_PLK2_PLK2_ST	P62258	YWHAE	Q9NYY3	PLK2	T218	L224S	224	Missense	distal	6	no	12.983	14.834	EPSD	COSMIC;GDSC;CCLE	13.807	Gain
Other_PLK_PLK2_PLK2_ST	P62258	YWHAE	Q9NYY3	PLK2	T232	R225H	225	Missense	distal	-7	no	13.704	14.029	EPSD	COSMIC	13.807	Gain
Other_PLK_PLK2_PLK2_ST	P62258	YWHAE	Q9NYY3	PLK2	T232	G237S	237	Missense	distal	5	no	13.704	13.867	EPSD	COSMIC	13.807	Gain
Other_PLK_PLK2_PLK2_ST	P62258	YWHAE	Q9NYY3	PLK2	S233	G239C	239	Missense	distal	6	no	11.775	14.144	EPSD	COSMIC	13.807	Gain
Other_PLK_PLK2_PLK2_ST	O43852	CALU	Q9NYY3	PLK2	S44	D46N	46	Missense	proximal	2	no	22.199	22.277	PhosphoSitePlus;EPSD	COSMIC;CCLE	13.807	Up-regulation
Other_PLK_PLK2_PLK2_ST	O43852	CALU	Q9NYY3	PLK2	S44	D41H	41	Missense	distal	-3	no	22.199	20.833	PhosphoSitePlus;EPSD	COSMIC	13.807	Down-regulation
Other_PLK_PLK2_PLK2_ST	O43852	CALU	Q9NYY3	PLK2	S44	K37T	37	Missense	distal	-7	no	22.199	21.173	PhosphoSitePlus;EPSD	COSMIC	13.807	Down-regulation
Other_PLK_PLK2_PLK2_ST	O43852	CALU	Q9NYY3	PLK2	T60	T65I	65	Missense	distal	5	no	19.937	19.682	EPSD;PhosphoSitePlus	COSMIC	13.807	Down-regulation
Other_PLK_PLK2_PLK2_ST	O43852	CALU	Q9NYY3	PLK2	T60	D62Y	62	Missense	proximal	2	no	19.937	20.106	EPSD;PhosphoSitePlus	COSMIC;GDSC;CCLE	13.807	Up-regulation
Other_PLK_PLK2_PLK2_ST	O43852	CALU	Q9NYY3	PLK2	T196	N203S	203	Missense	distal	7	no	20.269	19.132	EPSD;PhosphoSitePlus	COSMIC	13.807	Down-regulation
Other_PLK_PLK2_PLK2_ST	O43852	CALU	Q9NYY3	PLK2	T196	I200M	200	Missense	distal	4	no	20.269	20.996	EPSD;PhosphoSitePlus	COSMIC	13.807	Up-regulation
Other_PLK_PLK2_PLK2_ST	O43852	CALU	Q9NYY3	PLK2	T196	D190H	190	Missense	distal	-6	no	20.269	20.816	EPSD;PhosphoSitePlus	COSMIC	13.807	Up-regulation
Other_PLK_PLK2_PLK2_ST	P06748	NPM1	Q9NYY3	PLK2	S106	G113V	113	Missense	distal	7	no	15.403	13.399	EPSD	COSMIC	13.807	Loss
Other_PLK_PLK2_PLK2_ST	P06748	NPM1	Q9NYY3	PLK2	S106	I111N	111	Missense	distal	5	no	15.403	15.505	EPSD	COSMIC	13.807	Up-regulation
Other_PLK_PLK2_PLK2_ST	P06748	NPM1	Q9NYY3	PLK2	S195	P200S	200	Missense	distal	5	no	15.008	15.112	EPSD	COSMIC	13.807	Up-regulation
Other_PLK_PLK2_PLK2_ST	P06748	NPM1	Q9NYY3	PLK2	S195	S195F	195	Missense	central	0	yes	15.008	0.000	EPSD	COSMIC	13.807	Loss
Other_PLK_PLK2_PLK2_ST	P06748	NPM1	Q9NYY3	PLK2	S227	F228S	228	Missense	proximal	1	no	16.523	13.633	EPSD	COSMIC	13.807	Loss
Other_PLK_PLK2_PLK2_ST	P06748	NPM1	Q9NYY3	PLK2	S227	G224R	224	Missense	distal	-3	no	16.523	14.378	EPSD	COSMIC	13.807	Down-regulation
Other_PLK_PLK2_PLK2_ST	P06748	NPM1	Q9NYY3	PLK2	S227	S227F	227	Missense	central	0	yes	16.523	0.000	EPSD	COSMIC	13.807	Loss
Other_PLK_PLK2_PLK2_ST	P06748	NPM1	Q9NYY3	PLK2	S254	I255V	255	Missense	proximal	1	no	11.431	15.052	EPSD	COSMIC	13.807	Gain
Other_PLK_PLK2_PLK2_ST	P06748	NPM1	Q9NYY3	PLK2	S260	I255V	255	Missense	distal	-5	no	14.641	14.352	EPSD	COSMIC	13.807	Down-regulation
Other_PLK_PLK2_PLK2_ST	P06748	NPM1	Q9NYY3	PLK2	S260	K263E	263	Missense	distal	3	no	14.641	12.502	EPSD	COSMIC	13.807	Loss
Other_PLK_PLK2_PLK2_ST	P06748	NPM1	Q9NYY3	PLK2	S260	L261F	261	Missense	proximal	1	no	14.641	16.689	EPSD	COSMIC	13.807	Up-regulation
Other_PLK_PLK2_PLK2_ST	P06748	NPM1	Q9NYY3	PLK2	S260	S260C	260	Missense	central	0	yes	14.641	0.000	EPSD	COSMIC	13.807	Loss
Other_PLK_PLK2_PLK2_ST	Q969H0	FBXW7	Q9NYY3	PLK2	S10	L6F	6	Missense	distal	-4	no	13.508	13.904	EPSD	COSMIC	13.807	Gain
Other_PLK_PLK2_PLK2_ST	Q969H0	FBXW7	Q9NYY3	PLK2	S176	H174R	174	Missense	proximal	-2	no	20.125	20.437	PhosphoSitePlus;EPSD	COSMIC	13.807	Up-regulation
Other_PLK_PLK2_PLK2_ST	Q969H0	FBXW7	Q9NYY3	PLK2	S176	S180F	180	Missense	distal	4	no	20.125	21.584	PhosphoSitePlus;EPSD	COSMIC	13.807	Up-regulation
Other_PLK_PLK2_PLK2_ST	Q969H0	FBXW7	Q9NYY3	PLK2	S176	L172V	172	Missense	distal	-4	no	20.125	20.731	PhosphoSitePlus;EPSD	COSMIC	13.807	Up-regulation
Other_PLK_PLK2_PLK2_ST	Q969H0	FBXW7	Q9NYY3	PLK2	S176	L183P	183	Missense	distal	7	no	20.125	20.120	PhosphoSitePlus;EPSD	COSMIC	13.807	Down-regulation
Other_PLK_PLK2_PLK2_ST	Q969H0	FBXW7	Q9NYY3	PLK2	S349	G345D	345	Missense	distal	-4	no	20.972	19.637	EPSD;PhosphoSitePlus	COSMIC	13.807	Down-regulation
Other_PLK_PLK2_PLK2_ST	Q969H0	FBXW7	Q9NYY3	PLK2	S349	A354S	354	Missense	distal	5	no	20.972	20.885	EPSD;PhosphoSitePlus	COSMIC	13.807	Down-regulation
Other_PLK_PLK2_PLK2_ST	Q969H0	FBXW7	Q9NYY3	PLK2	S372	G378E	378	Missense	distal	6	no	11.928	14.521	EPSD	COSMIC	13.807	Gain
Other_PLK_PLK2_PLK2_ST	Q16143	SNCB	Q9NYY3	PLK2	S118	Y119F	119	Missense	proximal	1	no	13.950	19.171	PhosphoSitePlus	COSMIC	13.807	Up-regulation
Other_PLK_PLK2_PLK2_ST	Q16143	SNCB	Q9NYY3	PLK2	S118	M112K	112	Missense	distal	-6	no	13.950	13.495	PhosphoSitePlus	COSMIC	13.807	Loss
Other_PLK_PLK2_PLK2_ST	Q16143	SNCB	Q9NYY3	PLK2	S118	Y119C	119	Missense	proximal	1	no	13.950	16.708	PhosphoSitePlus	COSMIC	13.807	Up-regulation
Other_PLK_PLK2_PLK2_ST	Q16143	SNCB	Q9NYY3	PLK2	S118	Q124K	124	Missense	distal	6	no	13.950	14.229	PhosphoSitePlus	COSMIC	13.807	Up-regulation
Other_PLK_PLK2_PLK2_ST	Q16143	SNCB	Q9NYY3	PLK2	S118	E117A	117	Missense	proximal	-1	no	13.950	13.797	PhosphoSitePlus	COSMIC	13.807	Loss
Other_PLK_PLK2_PLK2_ST	P53350	PLK1	Q9NYY3	PLK2	T366	G367V	367	Missense	proximal	1	no	17.311	16.774	EPSD	COSMIC	13.807	Down-regulation
Other_PLK_PLK2_PLK2_ST	P53350	PLK1	Q9NYY3	PLK2	T366	R364Q	364	Missense	proximal	-2	no	17.311	17.644	EPSD	COSMIC;GDSC	13.807	Up-regulation
Other_PLK_PLK2_PLK2_ST	P53350	PLK1	Q9NYY3	PLK2	S450	G448V	448	Missense	proximal	-2	no	14.368	14.878	EPSD	COSMIC	13.807	Up-regulation
Other_PLK_PLK2_PLK2_ST	P53350	PLK1	Q9NYY3	PLK2	S578	K574T	574	Missense	distal	-4	no	14.998	15.892	EPSD	COSMIC	13.807	Up-regulation
Other_PLK_PLK2_PLK2_ST	P53350	PLK1	Q9NYY3	PLK2	S578	R581G	581	Missense	distal	3	no	14.998	12.535	EPSD	COSMIC	13.807	Loss
Other_PLK_PLK2_PLK2_ST	P53350	PLK1	Q9NYY3	PLK2	S578	R584H	584	Missense	distal	6	no	14.998	16.554	EPSD	COSMIC	13.807	Up-regulation
Other_PLK_PLK2_PLK2_ST	P53350	PLK1	Q9NYY3	PLK2	S578	A583V	583	Missense	distal	5	no	14.998	14.706	EPSD	COSMIC;CCLE	13.807	Down-regulation
Other_PLK_PLK2_PLK2_ST	P37840	SNCA	Q9NYY3	PLK2	S129	A124S	124	Missense	distal	-5	no	17.753	15.559	PhosphoSitePlus	COSMIC	13.807	Down-regulation
Other_PLK_PLK2_PLK2_ST	P37840	SNCA	Q9NYY3	PLK2	S129	E130V	130	Missense	proximal	1	no	17.753	18.895	PhosphoSitePlus	COSMIC	13.807	Up-regulation
Other_PLK_PLK2_PLK2_ST	P37840	SNCA	Q9NYY3	PLK2	S129	D135E	135	Missense	distal	6	no	17.753	17.858	PhosphoSitePlus	COSMIC;GDSC;CCLE	13.807	Up-regulation
Other_PLK_PLK2_PLK2_ST	P37840	SNCA	Q9NYY3	PLK2	S129	E130A	130	Missense	proximal	1	no	17.753	18.945	PhosphoSitePlus	COSMIC	13.807	Up-regulation
Other_PLK_PLK2_PLK2_ST	P37840	SNCA	Q9NYY3	PLK2	S129	E123K	123	Missense	distal	-6	no	17.753	17.969	PhosphoSitePlus	COSMIC	13.807	Up-regulation
TKL_RAF_RAF_ARAF_ST	Q92934	BAD	P10398	ARAF	S75	A78E	78	Missense	distal	3	no	6.566	6.536	PhosphoSitePlus;EPSD	COSMIC	2.916	Down-regulation
TKL_RAF_RAF_ARAF_ST	Q92934	BAD	P10398	ARAF	S99	P102L	102	Missense	distal	3	no	6.419	6.398	EPSD;PhosphoSitePlus	COSMIC	2.916	Down-regulation
TKL_RAF_RAF_ARAF_ST	Q92934	BAD	P10398	ARAF	S99	S97P	97	Missense	proximal	-2	no	6.419	6.321	EPSD;PhosphoSitePlus	COSMIC	2.916	Down-regulation
TKL_RAF_RAF_ARAF_ST	Q92934	BAD	P10398	ARAF	S99	R98H	98	Missense	proximal	-1	no	6.419	6.568	EPSD;PhosphoSitePlus	COSMIC	2.916	Up-regulation
TKL_RAF_RAF_ARAF_ST	Q92934	BAD	P10398	ARAF	S99	P101S	101	Missense	proximal	2	no	6.419	6.481	EPSD;PhosphoSitePlus	COSMIC	2.916	Up-regulation
TKL_RAF_RAF_ARAF_ST	Q92934	BAD	P10398	ARAF	S118	S124F	124	Missense	distal	6	no	6.098	6.063	EPSD;PhosphoSitePlus	COSMIC	2.916	Down-regulation
TKL_RAF_RAF_ARAF_ST	Q15599	SLC9A3R2	P10398	ARAF	S261	N266S	266	Missense	distal	5	no	3.333	3.184	EPSD	COSMIC	2.916	Down-regulation
TKL_RAF_RAF_ARAF_ST	Q15599	SLC9A3R2	P10398	ARAF	S261	G259E	259	Missense	proximal	-2	no	3.333	3.440	EPSD	COSMIC	2.916	Up-regulation
TKL_RAF_RAF_ARAF_ST	Q15599	SLC9A3R2	P10398	ARAF	S261	A263T	263	Missense	proximal	2	no	3.333	3.371	EPSD	COSMIC	2.916	Up-regulation
TKL_RAF_RAF_ARAF_ST	Q15599	SLC9A3R2	P10398	ARAF	S303	E297K	297	Missense	distal	-6	no	6.575	6.592	PhosphoSitePlus	COSMIC	2.916	Up-regulation
TKL_RAF_RAF_ARAF_ST	Q15599	SLC9A3R2	P10398	ARAF	S303	E308K	308	Missense	distal	5	no	6.575	6.641	PhosphoSitePlus	COSMIC	2.916	Up-regulation
TKL_RAF_RAF_ARAF_ST	Q02750	MAP2K1	P10398	ARAF	S218	S212N	212	Missense	distal	-6	no	6.728	6.751	EPSD;PhosphoSitePlus	COSMIC	2.916	Up-regulation
TKL_RAF_RAF_ARAF_ST	Q02750	MAP2K1	P10398	ARAF	S218	L215F	215	Missense	distal	-3	no	6.728	5.494	EPSD;PhosphoSitePlus	COSMIC	2.916	Down-regulation
TKL_RAF_RAF_ARAF_ST	Q02750	MAP2K1	P10398	ARAF	S218	G213V	213	Missense	distal	-5	no	6.728	6.667	EPSD;PhosphoSitePlus	COSMIC	2.916	Down-regulation
TKL_RAF_RAF_ARAF_ST	Q02750	MAP2K1	P10398	ARAF	S218	S218F	218	Missense	central	0	yes	6.728	0.000	EPSD;PhosphoSitePlus	COSMIC	2.916	Loss
TKL_RAF_RAF_ARAF_ST	Q02750	MAP2K1	P10398	ARAF	S222	L215F	215	Missense	distal	-7	no	6.846	6.845	PhosphoSitePlus;EPSD	COSMIC	2.916	Down-regulation
TKL_RAF_RAF_ARAF_ST	Q02750	MAP2K1	P10398	ARAF	S222	Y229H	229	Missense	distal	7	no	6.846	6.779	PhosphoSitePlus;EPSD	COSMIC	2.916	Down-regulation
TKL_RAF_RAF_ARAF_ST	Q02750	MAP2K1	P10398	ARAF	S222	S218F	218	Missense	distal	-4	no	6.846	6.705	PhosphoSitePlus;EPSD	COSMIC	2.916	Down-regulation
CMGC_DYRK_DYRK1_DYRK1B_ST	Q02363	ID2	Q9Y463	DYRK1B	S5	P6S	6	Missense	proximal	1	no	0.068	0.027	EPSD	COSMIC	0.062	Loss
CMGC_DYRK_DYRK1_DYRK1B_ST	Q02363	ID2	Q9Y463	DYRK1B	S5	S5C	5	Missense	central	0	yes	0.068	0.000	EPSD	COSMIC	0.062	Loss
CMGC_DYRK_DYRK1_DYRK1B_ST	Q02363	ID2	Q9Y463	DYRK1B	T27	T27A	27	Missense	central	0	yes	0.122	0.000	PhosphoSitePlus	COSMIC;GDSC;CCLE	0.062	Loss
CMGC_DYRK_DYRK1_DYRK1B_ST	Q02363	ID2	Q9Y463	DYRK1B	T27	R24W	24	Missense	distal	-3	no	0.122	0.089	PhosphoSitePlus	COSMIC	0.062	Down-regulation
CMGC_DYRK_DYRK1_DYRK1B_ST	Q9Y463	DYRK1B	Q9Y463	DYRK1B	S49	R46C	46	Missense	distal	-3	no	0.082	0.066	EPSD	COSMIC	0.062	Down-regulation
CMGC_DYRK_DYRK1_DYRK1B_ST	Q9Y463	DYRK1B	Q9Y463	DYRK1B	S121	G118C	118	Missense	distal	-3	no	0.046	0.067	EPSD	COSMIC	0.062	Gain
CMGC_DYRK_DYRK1_DYRK1B_ST	Q9Y463	DYRK1B	Q9Y463	DYRK1B	S421	R419H	419	Missense	proximal	-2	no	0.123	0.114	EPSD;PhosphoSitePlus	COSMIC	0.062	Down-regulation
CMGC_DYRK_DYRK1_DYRK1B_ST	Q9Y463	DYRK1B	Q9Y463	DYRK1B	S421	L423M	423	Missense	proximal	2	no	0.123	0.122	EPSD;PhosphoSitePlus	COSMIC	0.062	Down-regulation
CMGC_DYRK_DYRK1_DYRK1B_ST	Q9Y463	DYRK1B	Q9Y463	DYRK1B	S421	P422H	422	Missense	proximal	1	no	0.123	0.075	EPSD;PhosphoSitePlus	COSMIC	0.062	Down-regulation
CMGC_DYRK_DYRK1_DYRK1B_ST	Q9Y463	DYRK1B	Q9Y463	DYRK1B	S421	A418T	418	Missense	distal	-3	no	0.123	0.120	EPSD;PhosphoSitePlus	COSMIC	0.062	Down-regulation
CMGC_DYRK_DYRK1_DYRK1B_ST	Q9Y463	DYRK1B	Q9Y463	DYRK1B	S451	S446R	446	Missense	distal	-5	no	0.060	0.062	EPSD	COSMIC	0.062	Gain
CMGC_DYRK_DYRK1_DYRK1B_ST	Q9Y463	DYRK1B	Q9Y463	DYRK1B	S554	P552L	552	Missense	proximal	-2	no	0.101	0.097	EPSD	COSMIC;GDSC;CCLE	0.062	Down-regulation
CMGC_DYRK_DYRK1_DYRK1B_ST	Q9Y463	DYRK1B	Q9Y463	DYRK1B	S554	R551H	551	Missense	distal	-3	no	0.101	0.069	EPSD	COSMIC;GDSC;CCLE	0.062	Down-regulation
CMGC_DYRK_DYRK1_DYRK1B_ST	Q9Y463	DYRK1B	Q9Y463	DYRK1B	S554	P561L	561	Missense	distal	7	no	0.101	0.099	EPSD	COSMIC	0.062	Down-regulation
CMGC_DYRK_DYRK1_DYRK1B_ST	Q9Y463	DYRK1B	Q9Y463	DYRK1B	S557	P552L	552	Missense	distal	-5	no	0.059	0.062	EPSD	COSMIC;GDSC;CCLE	0.062	Gain
CMGC_DYRK_DYRK1_DYRK1B_ST	P24385	CCND1	Q9Y463	DYRK1B	S131	R133L	133	Missense	proximal	2	no	0.088	0.087	EPSD	COSMIC	0.062	Down-regulation
CMGC_DYRK_DYRK1_DYRK1B_ST	P24385	CCND1	Q9Y463	DYRK1B	S131	R133Q	133	Missense	proximal	2	no	0.088	0.087	EPSD	COSMIC	0.062	Down-regulation
CMGC_DYRK_DYRK1_DYRK1B_ST	P24385	CCND1	Q9Y463	DYRK1B	S131	D129N	129	Missense	proximal	-2	no	0.088	0.091	EPSD	COSMIC	0.062	Up-regulation
CMGC_DYRK_DYRK1_DYRK1B_ST	P24385	CCND1	Q9Y463	DYRK1B	S257	Q250H	250	Missense	distal	-7	no	0.070	0.072	EPSD	COSMIC;CCLE	0.062	Up-regulation
CMGC_DYRK_DYRK1_DYRK1B_ST	P24385	CCND1	Q9Y463	DYRK1B	T286	T286P	286	Missense	central	0	yes	0.074	0.000	EPSD	COSMIC	0.062	Loss
CMGC_DYRK_DYRK1_DYRK1B_ST	P24385	CCND1	Q9Y463	DYRK1B	T286	A284V	284	Missense	proximal	-2	no	0.074	0.072	EPSD	COSMIC	0.062	Down-regulation
CMGC_DYRK_DYRK1_DYRK1B_ST	P24385	CCND1	Q9Y463	DYRK1B	T286	E280V	280	Missense	distal	-6	no	0.074	0.075	EPSD	COSMIC;CCLE	0.062	Up-regulation
CMGC_DYRK_DYRK1_DYRK1B_ST	P24385	CCND1	Q9Y463	DYRK1B	T286	R291W	291	Missense	distal	5	no	0.074	0.078	EPSD	COSMIC;GDSC;CCLE	0.062	Up-regulation
CMGC_DYRK_DYRK1_DYRK1B_ST	P24385	CCND1	Q9Y463	DYRK1B	T286	R291L	291	Missense	distal	5	no	0.074	0.080	EPSD	COSMIC;GDSC;CCLE	0.062	Up-regulation
CMGC_DYRK_DYRK1_DYRK1B_ST	P24385	CCND1	Q9Y463	DYRK1B	T288	R291W	291	Missense	distal	3	no	0.077	0.079	PhosphoSitePlus	COSMIC;GDSC;CCLE	0.062	Up-regulation
CMGC_DYRK_DYRK1_DYRK1B_ST	P24385	CCND1	Q9Y463	DYRK1B	T288	R291L	291	Missense	distal	3	no	0.077	0.084	PhosphoSitePlus	COSMIC;GDSC;CCLE	0.062	Up-regulation
CMGC_DYRK_DYRK1_DYRK1B_ST	P24385	CCND1	Q9Y463	DYRK1B	T288	V290G	290	Missense	proximal	2	no	0.077	0.075	PhosphoSitePlus	COSMIC	0.062	Down-regulation
CMGC_DYRK_DYRK1_DYRK1B_ST	P38936	CDKN1A	Q9Y463	DYRK1B	T57	D62Y	62	Missense	distal	5	no	0.101	0.099	EPSD	COSMIC	0.062	Down-regulation
CMGC_DYRK_DYRK1_DYRK1B_ST	P38936	CDKN1A	Q9Y463	DYRK1B	T57	D62H	62	Missense	distal	5	no	0.101	0.098	EPSD	COSMIC	0.062	Down-regulation
CMGC_DYRK_DYRK1_DYRK1B_ST	P38936	CDKN1A	Q9Y463	DYRK1B	T57	D52V	52	Missense	distal	-5	no	0.101	0.103	EPSD	COSMIC	0.062	Up-regulation
CMGC_DYRK_DYRK1_DYRK1B_ST	P38936	CDKN1A	Q9Y463	DYRK1B	T57	T57R	57	Missense	central	0	yes	0.101	0.000	EPSD	COSMIC	0.062	Loss
CMGC_DYRK_DYRK1_DYRK1B_ST	P38936	CDKN1A	Q9Y463	DYRK1B	T97	G90R	90	Missense	distal	-7	no	0.106	0.103	EPSD	COSMIC	0.062	Down-regulation
CMGC_DYRK_DYRK1_DYRK1B_ST	P38936	CDKN1A	Q9Y463	DYRK1B	T97	T97I	97	Missense	central	0	yes	0.106	0.000	EPSD	COSMIC	0.062	Loss
CMGC_DYRK_DYRK1_DYRK1B_ST	P20823	HNF1A	Q9Y463	DYRK1B	T74	D77N	77	Missense	distal	3	no	0.066	0.060	EPSD	COSMIC	0.062	Loss
CMGC_DYRK_DYRK1_DYRK1B_ST	P20823	HNF1A	Q9Y463	DYRK1B	T74	G69A	69	Missense	distal	-5	no	0.066	0.068	EPSD	COSMIC	0.062	Up-regulation
CMGC_DYRK_DYRK1_DYRK1B_ST	P20823	HNF1A	Q9Y463	DYRK1B	T74	R68W	68	Missense	distal	-6	no	0.066	0.067	EPSD	COSMIC	0.062	Up-regulation
CMGC_DYRK_DYRK1_DYRK1B_ST	P20823	HNF1A	Q9Y463	DYRK1B	T74	D76Y	76	Missense	proximal	2	no	0.066	0.067	EPSD	COSMIC	0.062	Up-regulation
CMGC_DYRK_DYRK1_DYRK1B_ST	P20823	HNF1A	Q9Y463	DYRK1B	T74	E73K	73	Missense	proximal	-1	no	0.066	0.064	EPSD	COSMIC	0.062	Down-regulation
CMGC_DYRK_DYRK1_DYRK1B_ST	P20823	HNF1A	Q9Y463	DYRK1B	T82	D77N	77	Missense	distal	-5	no	0.107	0.110	EPSD	COSMIC	0.062	Up-regulation
CMGC_DYRK_DYRK1_DYRK1B_ST	P20823	HNF1A	Q9Y463	DYRK1B	T82	G78R	78	Missense	distal	-4	no	0.107	0.104	EPSD	COSMIC	0.062	Down-regulation
CMGC_DYRK_DYRK1_DYRK1B_ST	P20823	HNF1A	Q9Y463	DYRK1B	S93	A98V	98	Missense	distal	5	no	0.078	0.076	EPSD	COSMIC	0.062	Down-regulation
CMGC_DYRK_DYRK1_DYRK1B_ST	P20823	HNF1A	Q9Y463	DYRK1B	S93	A98G	98	Missense	distal	5	no	0.078	0.083	EPSD	COSMIC	0.062	Up-regulation
CMGC_DYRK_DYRK1_DYRK1B_ST	P20823	HNF1A	Q9Y463	DYRK1B	S247	Q250P	250	Missense	distal	3	no	0.144	0.146	EPSD	COSMIC	0.062	Up-regulation
CMGC_DYRK_DYRK1_DYRK1B_ST	P20823	HNF1A	Q9Y463	DYRK1B	S247	G245R	245	Missense	proximal	-2	no	0.144	0.152	EPSD	COSMIC	0.062	Up-regulation
CMGC_DYRK_DYRK1_DYRK1B_ST	P20823	HNF1A	Q9Y463	DYRK1B	S247	P248S	248	Missense	proximal	1	no	0.144	0.103	EPSD	COSMIC	0.062	Down-regulation
CMGC_DYRK_DYRK1_DYRK1B_ST	P20823	HNF1A	Q9Y463	DYRK1B	S247	R244S	244	Missense	distal	-3	no	0.144	0.124	EPSD	COSMIC	0.062	Down-regulation
CMGC_DYRK_DYRK1_DYRK1B_ST	P20823	HNF1A	Q9Y463	DYRK1B	S247	R244I	244	Missense	distal	-3	no	0.144	0.110	EPSD	COSMIC	0.062	Down-regulation
CMGC_DYRK_DYRK1_DYRK1B_ST	P20823	HNF1A	Q9Y463	DYRK1B	S249	Q250P	250	Missense	proximal	1	no	0.096	0.127	PhosphoSitePlus	COSMIC	0.062	Up-regulation
CMGC_DYRK_DYRK1_DYRK1B_ST	P20823	HNF1A	Q9Y463	DYRK1B	S249	G245R	245	Missense	distal	-4	no	0.096	0.093	PhosphoSitePlus	COSMIC	0.062	Down-regulation
CMGC_DYRK_DYRK1_DYRK1B_ST	P20823	HNF1A	Q9Y463	DYRK1B	S249	P248S	248	Missense	proximal	-1	no	0.096	0.097	PhosphoSitePlus	COSMIC	0.062	Up-regulation
CMGC_DYRK_DYRK1_DYRK1B_ST	P20823	HNF1A	Q9Y463	DYRK1B	S249	R244S	244	Missense	distal	-5	no	0.096	0.094	PhosphoSitePlus	COSMIC	0.062	Down-regulation
CMGC_DYRK_DYRK1_DYRK1B_ST	P20823	HNF1A	Q9Y463	DYRK1B	S249	R244I	244	Missense	distal	-5	no	0.096	0.091	PhosphoSitePlus	COSMIC	0.062	Down-regulation
CMGC_DYRK_DYRK1_DYRK1B_ST	P20823	HNF1A	Q9Y463	DYRK1B	S304	S303I	303	Missense	proximal	-1	no	0.065	0.066	EPSD	COSMIC	0.062	Up-regulation
CMGC_DYRK_DYRK1_DYRK1B_ST	P20823	HNF1A	Q9Y463	DYRK1B	S304	H302D	302	Missense	proximal	-2	no	0.065	0.066	EPSD	COSMIC	0.062	Up-regulation
CMGC_DYRK_DYRK1_DYRK1B_ST	P20823	HNF1A	Q9Y463	DYRK1B	S304	G306V	306	Missense	proximal	2	no	0.065	0.067	EPSD	COSMIC	0.062	Up-regulation
CMGC_DYRK_DYRK1_DYRK1B_ST	P20823	HNF1A	Q9Y463	DYRK1B	S304	A301S	301	Missense	distal	-3	no	0.065	0.070	EPSD	COSMIC	0.062	Up-regulation
CMGC_DYRK_DYRK1_DYRK1B_ST	P20823	HNF1A	Q9Y463	DYRK1B	S304	P305H	305	Missense	proximal	1	no	0.065	0.017	EPSD	COSMIC	0.062	Loss
CMGC_DYRK_DYRK1_DYRK1B_ST	P20823	HNF1A	Q9Y463	DYRK1B	S313	P310S	310	Missense	distal	-3	no	0.038	0.063	EPSD	COSMIC	0.062	Gain
CMGC_DYRK_DYRK1_DYRK1B_ST	O75533	SF3B1	Q9Y463	DYRK1B	S71	D68N	68	Missense	distal	-3	no	0.045	0.063	EPSD	COSMIC	0.062	Gain
CMGC_DYRK_DYRK1_DYRK1B_ST	O75533	SF3B1	Q9Y463	DYRK1B	S129	R132H	132	Missense	distal	3	no	0.090	0.092	EPSD	COSMIC	0.062	Up-regulation
CMGC_DYRK_DYRK1_DYRK1B_ST	O75533	SF3B1	Q9Y463	DYRK1B	T142	M147I	147	Missense	distal	5	no	0.060	0.062	EPSD	COSMIC	0.062	Gain
CMGC_DYRK_DYRK1_DYRK1B_ST	O75533	SF3B1	Q9Y463	DYRK1B	T142	D144N	144	Missense	proximal	2	no	0.060	0.062	EPSD	COSMIC	0.062	Gain
CMGC_DYRK_DYRK1_DYRK1B_ST	O75533	SF3B1	Q9Y463	DYRK1B	T223	P224S	224	Missense	proximal	1	no	0.074	0.032	EPSD	COSMIC	0.062	Loss
CMGC_DYRK_DYRK1_DYRK1B_ST	O75533	SF3B1	Q9Y463	DYRK1B	T223	Q220R	220	Missense	distal	-3	no	0.074	0.100	EPSD	COSMIC	0.062	Up-regulation
CMGC_DYRK_DYRK1_DYRK1B_ST	O75533	SF3B1	Q9Y463	DYRK1B	T223	D219E	219	Missense	distal	-4	no	0.074	0.073	EPSD	COSMIC	0.062	Down-regulation
CMGC_DYRK_DYRK1_DYRK1B_ST	O75533	SF3B1	Q9Y463	DYRK1B	T261	S259R	259	Missense	proximal	-2	no	0.077	0.079	EPSD	COSMIC	0.062	Up-regulation
CMGC_DYRK_DYRK1_DYRK1B_ST	O75533	SF3B1	Q9Y463	DYRK1B	T261	P256L	256	Missense	distal	-5	no	0.077	0.080	EPSD	COSMIC	0.062	Up-regulation
CMGC_DYRK_DYRK1_DYRK1B_ST	O75533	SF3B1	Q9Y463	DYRK1B	T296	W293R	293	Missense	distal	-3	no	0.031	0.064	EPSD	COSMIC	0.062	Gain
CMGC_DYRK_DYRK1_DYRK1B_ST	O75533	SF3B1	Q9Y463	DYRK1B	T303	K298I	298	Missense	distal	-5	no	0.063	0.059	EPSD	COSMIC	0.062	Loss
CMGC_DYRK_DYRK1_DYRK1B_ST	O75533	SF3B1	Q9Y463	DYRK1B	T303	P304L	304	Missense	proximal	1	no	0.063	-0.004	EPSD	COSMIC	0.062	Loss
CMGC_DYRK_DYRK1_DYRK1B_ST	O75533	SF3B1	Q9Y463	DYRK1B	T303	D302E	302	Missense	proximal	-1	no	0.063	0.066	EPSD	COSMIC	0.062	Up-regulation
CMGC_DYRK_DYRK1_DYRK1B_ST	O75533	SF3B1	Q9Y463	DYRK1B	S344	G347V	347	Missense	distal	3	no	0.071	0.063	EPSD	COSMIC	0.062	Down-regulation
CMGC_DYRK_DYRK1_DYRK1B_ST	O75533	SF3B1	Q9Y463	DYRK1B	T369	P363S	363	Missense	distal	-6	no	0.065	0.066	EPSD	COSMIC	0.062	Up-regulation
CMGC_DYRK_DYRK1_DYRK1B_ST	O75533	SF3B1	Q9Y463	DYRK1B	T369	P372S	372	Missense	distal	3	no	0.065	0.060	EPSD	COSMIC	0.062	Loss
CMGC_DYRK_DYRK1_DYRK1B_ST	O75533	SF3B1	Q9Y463	DYRK1B	T369	A364V	364	Missense	distal	-5	no	0.065	0.064	EPSD	COSMIC	0.062	Down-regulation
CMGC_DYRK_DYRK1_DYRK1B_ST	O75533	SF3B1	Q9Y463	DYRK1B	S400	E394D	394	Missense	distal	-6	no	0.088	0.090	EPSD	COSMIC	0.062	Up-regulation
CMGC_DYRK_DYRK1_DYRK1B_ST	O75533	SF3B1	Q9Y463	DYRK1B	S400	E402G	402	Missense	proximal	2	no	0.088	0.087	EPSD	COSMIC	0.062	Down-regulation
CMGC_DYRK_DYRK1_DYRK1B_ST	O75533	SF3B1	Q9Y463	DYRK1B	S400	D393Y	393	Missense	distal	-7	no	0.088	0.090	EPSD	COSMIC	0.062	Up-regulation
CMGC_DYRK_DYRK1_DYRK1B_ST	O75533	SF3B1	Q9Y463	DYRK1B	S400	R397H	397	Missense	distal	-3	no	0.088	0.057	EPSD	COSMIC	0.062	Loss
CMGC_DYRK_DYRK1_DYRK1B_ST	O75533	SF3B1	Q9Y463	DYRK1B	S488	E491G	491	Missense	distal	3	no	0.064	0.070	EPSD	COSMIC	0.062	Up-regulation
CMGC_DYRK_DYRK1_DYRK1B_ST	O75533	SF3B1	Q9Y463	DYRK1B	S488	D483Y	483	Missense	distal	-5	no	0.064	0.066	EPSD	COSMIC	0.062	Up-regulation
CMGC_DYRK_DYRK1_DYRK1B_ST	O75533	SF3B1	Q9Y463	DYRK1B	S488	R495I	495	Missense	distal	7	no	0.064	0.063	EPSD	COSMIC	0.062	Down-regulation
CMGC_DYRK_DYRK1_DYRK1B_ST	O75533	SF3B1	Q9Y463	DYRK1B	S488	V482I	482	Missense	distal	-6	no	0.064	0.063	EPSD	COSMIC	0.062	Down-regulation
CMGC_DYRK_DYRK1_DYRK1B_ST	O75533	SF3B1	Q9Y463	DYRK1B	T508	K505E	505	Missense	distal	-3	no	0.103	0.085	EPSD	COSMIC;GDSC;CCLE	0.062	Down-regulation
CMGC_DYRK_DYRK1_DYRK1B_ST	O75533	SF3B1	Q9Y463	DYRK1B	T508	K503R	503	Missense	distal	-5	no	0.103	0.104	EPSD	COSMIC	0.062	Up-regulation
CMGC_DYRK_DYRK1_DYRK1B_ST	O75533	SF3B1	Q9Y463	DYRK1B	T508	L502S	502	Missense	distal	-6	no	0.103	0.104	EPSD	COSMIC	0.062	Up-regulation
CMGC_DYRK_DYRK1_DYRK1B_ST	O75533	SF3B1	Q9Y463	DYRK1B	T508	N506S	506	Missense	proximal	-2	no	0.103	0.105	EPSD	COSMIC	0.062	Up-regulation
CMGC_DYRK_DYRK1_DYRK1B_ST	O75533	SF3B1	Q9Y463	DYRK1B	S541	D546Y	546	Missense	distal	5	no	0.071	0.069	EPSD	COSMIC	0.062	Down-regulation
CMGC_DYRK_DYRK1_DYRK1B_ST	O75533	SF3B1	Q9Y463	DYRK1B	S541	L536F	536	Missense	distal	-5	no	0.071	0.069	EPSD	COSMIC	0.062	Down-regulation
CMGC_DYRK_DYRK1_DYRK1B_ST	O75533	SF3B1	Q9Y463	DYRK1B	S541	S541F	541	Missense	central	0	yes	0.071	0.000	EPSD	COSMIC	0.062	Loss
CMGC_DYRK_DYRK1_DYRK1B_ST	O75533	SF3B1	Q9Y463	DYRK1B	S611	G605S	605	Missense	distal	-6	no	0.077	0.076	EPSD	COSMIC	0.062	Down-regulation
CMGC_DYRK_DYRK1_DYRK1B_ST	O75533	SF3B1	Q9Y463	DYRK1B	S611	S611F	611	Missense	central	0	yes	0.077	0.000	EPSD	COSMIC	0.062	Loss
CMGC_DYRK_DYRK1_DYRK1B_ST	O75533	SF3B1	Q9Y463	DYRK1B	T1170	P1171L	1171	Missense	proximal	1	no	0.073	0.006	EPSD	COSMIC	0.062	Loss
CMGC_DYRK_DYRK1_DYRK1B_ST	O75533	SF3B1	Q9Y463	DYRK1B	S1271	I1272V	1272	Missense	proximal	1	no	0.044	0.065	EPSD	COSMIC	0.062	Gain
CAMK_MAPKAPK_MNK_MKNK2_ST	P23246	SFPQ	Q9HBH9	MKNK2	S283	R287S	287	Missense	distal	4	no	32.280	32.512	PhosphoSitePlus;EPSD	COSMIC	18.660	Up-regulation
CAMK_MAPKAPK_MNK_MKNK2_ST	P23246	SFPQ	Q9HBH9	MKNK2	S283	N281K	281	Missense	proximal	-2	no	32.280	31.556	PhosphoSitePlus;EPSD	COSMIC	18.660	Down-regulation
CAMK_MAPKAPK_MNK_MKNK2_ST	P23246	SFPQ	Q9HBH9	MKNK2	S379	N377K	377	Missense	proximal	-2	no	20.561	19.837	EPSD	COSMIC	18.660	Down-regulation
CAMK_MAPKAPK_MNK_MKNK2_ST	P23246	SFPQ	Q9HBH9	MKNK2	S379	R376L	376	Missense	distal	-3	no	20.561	18.323	EPSD	COSMIC;CCLE	18.660	Loss
CAMK_MAPKAPK_MNK_MKNK2_ST	P23246	SFPQ	Q9HBH9	MKNK2	S379	R376C	376	Missense	distal	-3	no	20.561	18.788	EPSD	COSMIC;CCLE	18.660	Down-regulation
CAMK_MAPKAPK_MNK_MKNK2_ST	O43597	SPRY2	Q9HBH9	MKNK2	S97	H96P	96	Missense	proximal	-1	no	18.667	18.737	EPSD	COSMIC	18.660	Up-regulation
CAMK_MAPKAPK_MNK_MKNK2_ST	O43597	SPRY2	Q9HBH9	MKNK2	S97	R104G	104	Missense	distal	7	no	18.667	18.814	EPSD	COSMIC	18.660	Up-regulation
CAMK_MAPKAPK_MNK_MKNK2_ST	O43597	SPRY2	Q9HBH9	MKNK2	S112	T113M	113	Missense	proximal	1	no	31.862	29.900	PhosphoSitePlus;EPSD	COSMIC	18.660	Down-regulation
CAMK_MAPKAPK_MNK_MKNK2_ST	O43597	SPRY2	Q9HBH9	MKNK2	S120	T113M	113	Missense	distal	-7	no	21.544	21.884	EPSD	COSMIC	18.660	Up-regulation
CAMK_MAPKAPK_MNK_MKNK2_ST	O43597	SPRY2	Q9HBH9	MKNK2	S120	R123K	123	Missense	distal	3	no	21.544	21.549	EPSD	COSMIC	18.660	Up-regulation
CAMK_MAPKAPK_MNK_MKNK2_ST	O43597	SPRY2	Q9HBH9	MKNK2	S121	R123K	123	Missense	proximal	2	no	31.478	30.812	EPSD;PhosphoSitePlus	COSMIC	18.660	Down-regulation
CAMK_MAPKAPK_MNK_MKNK2_ST	O43597	SPRY2	Q9HBH9	MKNK2	T122	R123K	123	Missense	proximal	1	no	21.489	20.837	EPSD	COSMIC	18.660	Down-regulation
CAMK_MAPKAPK_MNK_MKNK2_ST	O43597	SPRY2	Q9HBH9	MKNK2	T124	R123K	123	Missense	proximal	-1	no	19.649	19.612	EPSD	COSMIC	18.660	Down-regulation
CAMK_MAPKAPK_MNK_MKNK2_ST	O43597	SPRY2	Q9HBH9	MKNK2	T124	S130F	130	Missense	distal	6	no	19.649	18.778	EPSD	COSMIC	18.660	Down-regulation
CAMK_MAPKAPK_MNK_MKNK2_ST	O43597	SPRY2	Q9HBH9	MKNK2	S128	Q133R	133	Missense	distal	5	no	18.104	18.834	EPSD	COSMIC	18.660	Gain
CAMK_MAPKAPK_MNK_MKNK2_ST	O43597	SPRY2	Q9HBH9	MKNK2	S138	S141F	141	Missense	distal	3	no	18.707	18.678	EPSD	COSMIC	18.660	Down-regulation
CAMK_MAPKAPK_MNK_MKNK2_ST	O43597	SPRY2	Q9HBH9	MKNK2	S138	Q133R	133	Missense	distal	-5	no	18.707	18.773	EPSD	COSMIC	18.660	Up-regulation
CAMK_MAPKAPK_MNK_MKNK2_ST	O43597	SPRY2	Q9HBH9	MKNK2	S141	D147N	147	Missense	distal	6	no	19.039	19.776	EPSD	COSMIC	18.660	Up-regulation
CAMK_MAPKAPK_MNK_MKNK2_ST	O43597	SPRY2	Q9HBH9	MKNK2	S141	S141F	141	Missense	central	0	yes	19.039	0.000	EPSD	COSMIC	18.660	Loss
CAMK_MAPKAPK_MNK_MKNK2_ST	P06730	EIF4E	Q9HBH9	MKNK2	T203	G196A	196	Missense	distal	-7	no	19.135	19.722	EPSD	COSMIC	18.660	Up-regulation
CAMK_MAPKAPK_MNK_MKNK2_ST	P06730	EIF4E	Q9HBH9	MKNK2	S209	R214G	214	Missense	distal	5	no	32.281	34.802	PhosphoSitePlus	COSMIC	18.660	Up-regulation
CAMK_MAPKAPK_MNK_MKNK2_ST	Q15149	PLEC	Q9HBH9	MKNK2	S387	I388T	388	Missense	proximal	1	no	17.452	19.157	EPSD	COSMIC	18.660	Gain
CAMK_MAPKAPK_MNK_MKNK2_ST	Q15149	PLEC	Q9HBH9	MKNK2	S714	R713W	713	Missense	proximal	-1	no	22.482	22.293	EPSD	COSMIC	18.660	Down-regulation
CAMK_MAPKAPK_MNK_MKNK2_ST	Q15149	PLEC	Q9HBH9	MKNK2	S714	G717V	717	Missense	distal	3	no	22.482	22.215	EPSD	COSMIC	18.660	Down-regulation
CAMK_MAPKAPK_MNK_MKNK2_ST	Q15149	PLEC	Q9HBH9	MKNK2	S714	R711Q	711	Missense	distal	-3	no	22.482	21.865	EPSD	COSMIC	18.660	Down-regulation
CAMK_MAPKAPK_MNK_MKNK2_ST	Q15149	PLEC	Q9HBH9	MKNK2	S720	R724H	724	Missense	distal	4	no	18.985	18.513	EPSD	COSMIC	18.660	Loss
CAMK_MAPKAPK_MNK_MKNK2_ST	Q15149	PLEC	Q9HBH9	MKNK2	S720	A726V	726	Missense	distal	6	no	18.985	17.127	EPSD	COSMIC	18.660	Loss
CAMK_MAPKAPK_MNK_MKNK2_ST	Q15149	PLEC	Q9HBH9	MKNK2	S720	A722V	722	Missense	proximal	2	no	18.985	20.515	EPSD	COSMIC	18.660	Up-regulation
CAMK_MAPKAPK_MNK_MKNK2_ST	Q15149	PLEC	Q9HBH9	MKNK2	S720	R713W	713	Missense	distal	-7	no	18.985	18.602	EPSD	COSMIC	18.660	Loss
CAMK_MAPKAPK_MNK_MKNK2_ST	Q15149	PLEC	Q9HBH9	MKNK2	S720	G717V	717	Missense	distal	-3	no	18.985	17.540	EPSD	COSMIC	18.660	Loss
CAMK_MAPKAPK_MNK_MKNK2_ST	Q15149	PLEC	Q9HBH9	MKNK2	S984	S984I	984	Missense	central	0	yes	19.469	0.000	EPSD	COSMIC	18.660	Loss
CAMK_MAPKAPK_MNK_MKNK2_ST	Q15149	PLEC	Q9HBH9	MKNK2	S984	A987T	987	Missense	distal	3	no	19.469	19.467	EPSD	COSMIC	18.660	Down-regulation
CAMK_MAPKAPK_MNK_MKNK2_ST	Q15149	PLEC	Q9HBH9	MKNK2	S984	S984R	984	Missense	central	0	yes	19.469	0.000	EPSD	COSMIC;CCLE	18.660	Loss
CAMK_MAPKAPK_MNK_MKNK2_ST	Q15149	PLEC	Q9HBH9	MKNK2	S984	S984N	984	Missense	central	0	yes	19.469	0.000	EPSD	COSMIC	18.660	Loss
CAMK_MAPKAPK_MNK_MKNK2_ST	Q15149	PLEC	Q9HBH9	MKNK2	S984	G983S	983	Missense	proximal	-1	no	19.469	19.621	EPSD	COSMIC	18.660	Up-regulation
CAMK_MAPKAPK_MNK_MKNK2_ST	Q15149	PLEC	Q9HBH9	MKNK2	S1077	A1072V	1072	Missense	distal	-5	no	21.422	21.194	EPSD	COSMIC	18.660	Down-regulation
CAMK_MAPKAPK_MNK_MKNK2_ST	Q15149	PLEC	Q9HBH9	MKNK2	S1077	D1079G	1079	Missense	proximal	2	no	21.422	20.716	EPSD	COSMIC	18.660	Down-regulation
CAMK_MAPKAPK_MNK_MKNK2_ST	Q15149	PLEC	Q9HBH9	MKNK2	S2833	R2826Q	2826	Missense	distal	-7	no	20.446	20.234	EPSD	COSMIC	18.660	Down-regulation
CAMK_MAPKAPK_MNK_MKNK2_ST	Q15149	PLEC	Q9HBH9	MKNK2	S2833	L2829P	2829	Missense	distal	-4	no	20.446	21.131	EPSD	COSMIC	18.660	Up-regulation
CAMK_MAPKAPK_MNK_MKNK2_ST	Q15149	PLEC	Q9HBH9	MKNK2	S2833	R2832H	2832	Missense	proximal	-1	no	20.446	20.273	EPSD	COSMIC	18.660	Down-regulation
CAMK_MAPKAPK_MNK_MKNK2_ST	Q15149	PLEC	Q9HBH9	MKNK2	S2833	G2837S	2837	Missense	distal	4	no	20.446	20.458	EPSD	COSMIC	18.660	Up-regulation
CAMK_MAPKAPK_MNK_MKNK2_ST	Q15149	PLEC	Q9HBH9	MKNK2	S2833	Q2830R	2830	Missense	distal	-3	no	20.446	21.063	EPSD	COSMIC	18.660	Up-regulation
CAMK_MAPKAPK_MNK_MKNK2_ST	Q15149	PLEC	Q9HBH9	MKNK2	S2833	S2834N	2834	Missense	proximal	1	no	20.446	18.292	EPSD	COSMIC	18.660	Loss
CAMK_MAPKAPK_MNK_MKNK2_ST	Q15149	PLEC	Q9HBH9	MKNK2	S3048	A3049T	3049	Missense	proximal	1	no	17.930	18.952	EPSD	COSMIC	18.660	Gain
CAMK_MAPKAPK_MNK_MKNK2_ST	Q15149	PLEC	Q9HBH9	MKNK2	S3116	E3122K	3122	Missense	distal	6	no	17.348	19.353	EPSD	COSMIC	18.660	Gain
CAMK_MAPKAPK_MNK_MKNK2_ST	Q15149	PLEC	Q9HBH9	MKNK2	S3319	S3319N	3319	Missense	central	0	yes	21.037	0.000	EPSD	COSMIC	18.660	Loss
CAMK_MAPKAPK_MNK_MKNK2_ST	Q15149	PLEC	Q9HBH9	MKNK2	S3319	R3312M	3312	Missense	distal	-7	no	21.037	21.014	EPSD	COSMIC	18.660	Down-regulation
CAMK_MAPKAPK_MNK_MKNK2_ST	Q15149	PLEC	Q9HBH9	MKNK2	S3319	G3324W	3324	Missense	distal	5	no	21.037	18.173	EPSD	COSMIC	18.660	Loss
CAMK_MAPKAPK_MNK_MKNK2_ST	Q15149	PLEC	Q9HBH9	MKNK2	S3319	S3322N	3322	Missense	distal	3	no	21.037	21.011	EPSD	COSMIC	18.660	Down-regulation
CAMK_MAPKAPK_MNK_MKNK2_ST	Q15149	PLEC	Q9HBH9	MKNK2	S3322	S3319N	3319	Missense	distal	-3	no	20.899	19.977	EPSD	COSMIC	18.660	Down-regulation
CAMK_MAPKAPK_MNK_MKNK2_ST	Q15149	PLEC	Q9HBH9	MKNK2	S3322	G3324W	3324	Missense	proximal	2	no	20.899	21.374	EPSD	COSMIC	18.660	Up-regulation
CAMK_MAPKAPK_MNK_MKNK2_ST	Q15149	PLEC	Q9HBH9	MKNK2	S3322	S3322N	3322	Missense	central	0	yes	20.899	0.000	EPSD	COSMIC	18.660	Loss
CAMK_MAPKAPK_MNK_MKNK2_ST	Q15149	PLEC	Q9HBH9	MKNK2	T3785	E3791G	3791	Missense	distal	6	no	15.564	19.121	EPSD	COSMIC;GDSC;CCLE	18.660	Gain
CAMK_MAPKAPK_MNK_MKNK2_ST	Q15149	PLEC	Q9HBH9	MKNK2	S3975	T3970A	3970	Missense	distal	-5	no	18.730	18.701	EPSD	COSMIC	18.660	Down-regulation
CAMK_MAPKAPK_MNK_MKNK2_ST	Q15149	PLEC	Q9HBH9	MKNK2	S3975	R3981H	3981	Missense	distal	6	no	18.730	18.317	EPSD	COSMIC	18.660	Loss
CAMK_MAPKAPK_MNK_MKNK2_ST	Q15149	PLEC	Q9HBH9	MKNK2	T3988	R3981H	3981	Missense	distal	-7	no	20.047	19.357	EPSD	COSMIC	18.660	Down-regulation
CAMK_MAPKAPK_MNK_MKNK2_ST	Q15149	PLEC	Q9HBH9	MKNK2	T3988	R3991H	3991	Missense	distal	3	no	20.047	20.005	EPSD	COSMIC	18.660	Down-regulation
CAMK_MAPKAPK_MNK_MKNK2_ST	Q15149	PLEC	Q9HBH9	MKNK2	S4271	S4272L	4272	Missense	proximal	1	no	20.075	18.092	EPSD	COSMIC	18.660	Loss
CAMK_MAPKAPK_MNK_MKNK2_ST	Q15149	PLEC	Q9HBH9	MKNK2	S4271	S4271L	4271	Missense	central	0	yes	20.075	0.000	EPSD	COSMIC	18.660	Loss
CAMK_MAPKAPK_MNK_MKNK2_ST	Q15149	PLEC	Q9HBH9	MKNK2	S4271	S4272F	4272	Missense	proximal	1	no	20.075	19.450	EPSD	COSMIC	18.660	Down-regulation
CAMK_MAPKAPK_MNK_MKNK2_ST	Q15149	PLEC	Q9HBH9	MKNK2	S4271	R4265W	4265	Missense	distal	-6	no	20.075	20.047	EPSD	COSMIC;GDSC;CCLE	18.660	Down-regulation
CAMK_MAPKAPK_MNK_MKNK2_ST	Q15149	PLEC	Q9HBH9	MKNK2	S4271	R4274H	4274	Missense	distal	3	no	20.075	20.033	EPSD	COSMIC	18.660	Down-regulation
CAMK_MAPKAPK_MNK_MKNK2_ST	Q15149	PLEC	Q9HBH9	MKNK2	S4382	A4377V	4377	Missense	distal	-5	no	19.158	18.930	EPSD	COSMIC	18.660	Down-regulation
CAMK_MAPKAPK_MNK_MKNK2_ST	Q15149	PLEC	Q9HBH9	MKNK2	S4382	A4377T	4377	Missense	distal	-5	no	19.158	19.188	EPSD	COSMIC;GDSC	18.660	Up-regulation
CAMK_MAPKAPK_MNK_MKNK2_ST	Q15149	PLEC	Q9HBH9	MKNK2	S4382	S4386L	4386	Missense	distal	4	no	19.158	17.919	EPSD	COSMIC	18.660	Loss
CAMK_MAPKAPK_MNK_MKNK2_ST	Q15149	PLEC	Q9HBH9	MKNK2	S4384	A4377V	4377	Missense	distal	-7	no	21.702	22.460	EPSD	COSMIC	18.660	Up-regulation
CAMK_MAPKAPK_MNK_MKNK2_ST	Q15149	PLEC	Q9HBH9	MKNK2	S4384	A4377T	4377	Missense	distal	-7	no	21.702	21.807	EPSD	COSMIC;GDSC	18.660	Up-regulation
CAMK_MAPKAPK_MNK_MKNK2_ST	Q15149	PLEC	Q9HBH9	MKNK2	S4384	S4386L	4386	Missense	proximal	2	no	21.702	22.839	EPSD	COSMIC	18.660	Up-regulation
CAMK_MAPKAPK_MNK_MKNK2_ST	Q15149	PLEC	Q9HBH9	MKNK2	S4386	S4392Y	4392	Missense	distal	6	no	20.257	17.859	EPSD	COSMIC	18.660	Loss
CAMK_MAPKAPK_MNK_MKNK2_ST	Q15149	PLEC	Q9HBH9	MKNK2	S4386	S4386L	4386	Missense	central	0	yes	20.257	0.000	EPSD	COSMIC	18.660	Loss
CAMK_MAPKAPK_MNK_MKNK2_ST	Q15149	PLEC	Q9HBH9	MKNK2	S4386	Y4393H	4393	Missense	distal	7	no	20.257	20.419	EPSD	COSMIC	18.660	Up-regulation
CAMK_MAPKAPK_MNK_MKNK2_ST	Q15149	PLEC	Q9HBH9	MKNK2	S4386	S4392F	4392	Missense	distal	6	no	20.257	19.386	EPSD	COSMIC	18.660	Down-regulation
CAMK_MAPKAPK_MNK_MKNK2_ST	Q15149	PLEC	Q9HBH9	MKNK2	S4400	A4405S	4405	Missense	distal	5	no	17.499	18.740	EPSD	COSMIC	18.660	Gain
CAMK_MAPKAPK_MNK_MKNK2_ST	Q15149	PLEC	Q9HBH9	MKNK2	S4616	K4609Q	4609	Missense	distal	-7	no	21.918	22.613	EPSD	COSMIC;CCLE	18.660	Up-regulation
CAMK_MAPKAPK_MNK_MKNK2_ST	Q15149	PLEC	Q9HBH9	MKNK2	S4616	P4614S	4614	Missense	proximal	-2	no	21.918	25.749	EPSD	COSMIC	18.660	Up-regulation
CAMK_MAPKAPK_MNK_MKNK2_ST	Q15149	PLEC	Q9HBH9	MKNK2	S4616	G4621S	4621	Missense	distal	5	no	21.918	20.171	EPSD	COSMIC	18.660	Down-regulation
CAMK_MAPKAPK_MNK_MKNK2_ST	Q15149	PLEC	Q9HBH9	MKNK2	S4616	T4623A	4623	Missense	distal	7	no	21.918	21.916	EPSD	COSMIC	18.660	Down-regulation
CAMK_MAPKAPK_MNK_MKNK2_ST	Q15149	PLEC	Q9HBH9	MKNK2	T4628	G4625S	4625	Missense	distal	-3	no	19.482	20.822	EPSD	COSMIC	18.660	Up-regulation
CAMK_MAPKAPK_MNK_MKNK2_ST	Q15149	PLEC	Q9HBH9	MKNK2	T4628	G4621S	4621	Missense	distal	-7	no	19.482	20.155	EPSD	COSMIC	18.660	Up-regulation
CAMK_MAPKAPK_MNK_MKNK2_ST	Q15149	PLEC	Q9HBH9	MKNK2	T4628	G4629S	4629	Missense	proximal	1	no	19.482	22.369	EPSD	COSMIC	18.660	Up-regulation
CAMK_MAPKAPK_MNK_MKNK2_ST	Q15149	PLEC	Q9HBH9	MKNK2	T4628	R4631P	4631	Missense	distal	3	no	19.482	19.462	EPSD	COSMIC	18.660	Down-regulation
CAMK_MAPKAPK_MNK_MKNK2_ST	Q15149	PLEC	Q9HBH9	MKNK2	T4628	T4623A	4623	Missense	distal	-5	no	19.482	19.453	EPSD	COSMIC	18.660	Down-regulation
CAMK_MAPKAPK_MNK_MKNK2_ST	Q15149	PLEC	Q9HBH9	MKNK2	S4630	G4625S	4625	Missense	distal	-5	no	18.991	18.877	EPSD	COSMIC	18.660	Down-regulation
CAMK_MAPKAPK_MNK_MKNK2_ST	Q15149	PLEC	Q9HBH9	MKNK2	S4630	G4629S	4629	Missense	proximal	-1	no	18.991	19.143	EPSD	COSMIC	18.660	Up-regulation
CAMK_MAPKAPK_MNK_MKNK2_ST	Q15149	PLEC	Q9HBH9	MKNK2	S4630	G4637A	4637	Missense	distal	7	no	18.991	18.830	EPSD	COSMIC	18.660	Down-regulation
CAMK_MAPKAPK_MNK_MKNK2_ST	Q15149	PLEC	Q9HBH9	MKNK2	S4630	R4631P	4631	Missense	proximal	1	no	18.991	17.490	EPSD	COSMIC	18.660	Loss
CAMK_MAPKAPK_MNK_MKNK2_ST	Q15149	PLEC	Q9HBH9	MKNK2	S4630	T4623A	4623	Missense	distal	-7	no	18.991	18.886	EPSD	COSMIC	18.660	Down-regulation
CAMK_MAPKAPK_MNK_MKNK2_ST	Q15149	PLEC	Q9HBH9	MKNK2	T4632	G4629S	4629	Missense	distal	-3	no	17.685	19.024	EPSD	COSMIC	18.660	Gain
CAMK_MAPKAPK_MNK_MKNK2_ST	Q15149	PLEC	Q9HBH9	MKNK2	S4642	G4641C	4641	Missense	proximal	-1	no	30.335	30.094	PhosphoSitePlus	COSMIC	18.660	Down-regulation
CAMK_MAPKAPK_MNK_MKNK2_ST	Q15149	PLEC	Q9HBH9	MKNK2	S4642	G4637A	4637	Missense	distal	-5	no	30.335	30.132	PhosphoSitePlus	COSMIC	18.660	Down-regulation
CAMK_MAPKAPK_MNK_MKNK2_ST	Q15149	PLEC	Q9HBH9	MKNK2	S4642	R4639H	4639	Missense	distal	-3	no	30.335	28.834	PhosphoSitePlus	COSMIC	18.660	Down-regulation
CAMK_MAPKAPK_MNK_MKNK2_ST	Q15149	PLEC	Q9HBH9	MKNK2	S4657	S4661T	4661	Missense	distal	4	no	22.016	21.427	EPSD	COSMIC	18.660	Down-regulation
CAMK_MAPKAPK_MNK_MKNK2_ST	Q15149	PLEC	Q9HBH9	MKNK2	S4658	S4661T	4661	Missense	distal	3	no	20.966	20.916	EPSD	COSMIC	18.660	Down-regulation
CAMK_MAPKAPK_MNK_MKNK2_ST	Q15149	PLEC	Q9HBH9	MKNK2	S4661	R4666L	4666	Missense	distal	5	no	20.053	18.614	EPSD	COSMIC	18.660	Loss
CAMK_MAPKAPK_MNK_MKNK2_ST	Q15149	PLEC	Q9HBH9	MKNK2	S4661	R4666C	4666	Missense	distal	5	no	20.053	19.151	EPSD	COSMIC	18.660	Down-regulation
CAMK_MAPKAPK_MNK_MKNK2_ST	Q15149	PLEC	Q9HBH9	MKNK2	S4662	R4666L	4666	Missense	distal	4	no	19.122	18.115	EPSD	COSMIC	18.660	Loss
CAMK_MAPKAPK_MNK_MKNK2_ST	Q15149	PLEC	Q9HBH9	MKNK2	S4662	S4661T	4661	Missense	proximal	-1	no	19.122	18.911	EPSD	COSMIC	18.660	Down-regulation
CAMK_MAPKAPK_MNK_MKNK2_ST	Q15149	PLEC	Q9HBH9	MKNK2	S4662	R4666C	4666	Missense	distal	4	no	19.122	18.378	EPSD	COSMIC	18.660	Loss
CAMK_MAPKAPK_MNK_MKNK2_ST	Q15149	PLEC	Q9HBH9	MKNK2	S4672	R4666L	4666	Missense	distal	-6	no	21.564	21.509	EPSD	COSMIC	18.660	Down-regulation
CAMK_MAPKAPK_MNK_MKNK2_ST	Q15149	PLEC	Q9HBH9	MKNK2	S4672	G4678C	4678	Missense	distal	6	no	21.564	18.481	EPSD	COSMIC	18.660	Loss
CAMK_MAPKAPK_MNK_MKNK2_ST	Q15149	PLEC	Q9HBH9	MKNK2	S4672	R4666C	4666	Missense	distal	-6	no	21.564	21.514	EPSD	COSMIC	18.660	Down-regulation
CAMK_MAPKAPK_MNK_MKNK2_ST	Q15149	PLEC	Q9HBH9	MKNK2	S4673	R4666L	4666	Missense	distal	-7	no	22.050	22.180	EPSD	COSMIC	18.660	Up-regulation
CAMK_MAPKAPK_MNK_MKNK2_ST	Q15149	PLEC	Q9HBH9	MKNK2	S4673	G4678C	4678	Missense	distal	5	no	22.050	18.627	EPSD	COSMIC	18.660	Loss
CAMK_MAPKAPK_MNK_MKNK2_ST	Q15149	PLEC	Q9HBH9	MKNK2	S4673	R4666C	4666	Missense	distal	-7	no	22.050	21.755	EPSD	COSMIC	18.660	Down-regulation
CAMK_MAPKAPK_MNK_MKNK2_ST	Q15149	PLEC	Q9HBH9	MKNK2	S4675	G4678C	4678	Missense	distal	3	no	23.724	23.516	EPSD	COSMIC	18.660	Down-regulation
CAMK_PIM_PIM3_ST	Q92934	BAD	Q86V86	PIM3	S34	A27T	27	Missense	distal	-7	no	4.013	3.430	EPSD	COSMIC;GDSC;CCLE	3.716	Loss
CAMK_PIM_PIM3_ST	Q92934	BAD	Q86V86	PIM3	S57	E53K	53	Missense	distal	-4	no	4.226	4.432	EPSD	COSMIC	3.716	Up-regulation
CAMK_PIM_PIM3_ST	Q92934	BAD	Q86V86	PIM3	S57	S59R	59	Missense	proximal	2	no	4.226	4.283	EPSD	COSMIC	3.716	Up-regulation
CAMK_PIM_PIM3_ST	Q92934	BAD	Q86V86	PIM3	S75	A78E	78	Missense	distal	3	no	9.418	9.341	PhosphoSitePlus	COSMIC	3.716	Down-regulation
CAMK_PIM_PIM3_ST	Q92934	BAD	Q86V86	PIM3	S99	P102L	102	Missense	distal	3	no	4.680	4.727	EPSD	COSMIC	3.716	Up-regulation
CAMK_PIM_PIM3_ST	Q92934	BAD	Q86V86	PIM3	S99	S97P	97	Missense	proximal	-2	no	4.680	4.809	EPSD	COSMIC	3.716	Up-regulation
CAMK_PIM_PIM3_ST	Q92934	BAD	Q86V86	PIM3	S99	R98H	98	Missense	proximal	-1	no	4.680	4.437	EPSD	COSMIC	3.716	Down-regulation
CAMK_PIM_PIM3_ST	Q92934	BAD	Q86V86	PIM3	S99	P101S	101	Missense	proximal	2	no	4.680	4.663	EPSD	COSMIC	3.716	Down-regulation
CAMK_PIM_PIM3_ST	Q92934	BAD	Q86V86	PIM3	S134	K127N	127	Missense	distal	-7	no	4.190	3.966	EPSD	COSMIC	3.716	Down-regulation
CAMK_PIM_PIM3_ST	Q92934	BAD	Q86V86	PIM3	S134	K133N	133	Missense	proximal	-1	no	4.190	4.227	EPSD	COSMIC	3.716	Up-regulation
CAMK_PIM_PIM3_ST	Q92934	BAD	Q86V86	PIM3	T137	K133N	133	Missense	distal	-4	no	4.733	4.952	EPSD	COSMIC	3.716	Up-regulation
CAMK_PIM_PIM3_ST	Q92934	BAD	Q86V86	PIM3	S145	W147R	147	Missense	proximal	2	no	4.030	3.999	EPSD	COSMIC	3.716	Down-regulation
CAMK_PIM_PIM3_ST	Q92934	BAD	Q86V86	PIM3	T148	W147R	147	Missense	proximal	-1	no	3.864	4.234	EPSD	COSMIC	3.716	Up-regulation
CAMK_PIM_PIM3_ST	P35568	IRS1	Q86V86	PIM3	S189	Y183C	183	Missense	distal	-6	no	3.555	3.736	EPSD	COSMIC	3.716	Gain
CAMK_PIM_PIM3_ST	P35568	IRS1	Q86V86	PIM3	S270	R265C	265	Missense	distal	-5	no	4.559	3.104	EPSD	COSMIC	3.716	Loss
CAMK_PIM_PIM3_ST	P35568	IRS1	Q86V86	PIM3	S270	S274P	274	Missense	distal	4	no	4.559	4.356	EPSD	COSMIC	3.716	Down-regulation
CAMK_PIM_PIM3_ST	P35568	IRS1	Q86V86	PIM3	S272	R265C	265	Missense	distal	-7	no	3.286	3.779	EPSD	COSMIC	3.716	Gain
CAMK_PIM_PIM3_ST	P35568	IRS1	Q86V86	PIM3	S295	P292S	292	Missense	distal	-3	no	3.213	4.511	EPSD	COSMIC	3.716	Gain
CAMK_PIM_PIM3_ST	P35568	IRS1	Q86V86	PIM3	T305	R301C	301	Missense	distal	-4	no	4.386	5.081	EPSD	COSMIC	3.716	Up-regulation
CAMK_PIM_PIM3_ST	P35568	IRS1	Q86V86	PIM3	T305	E306K	306	Missense	proximal	1	no	4.386	4.419	EPSD	COSMIC	3.716	Up-regulation
CAMK_PIM_PIM3_ST	P35568	IRS1	Q86V86	PIM3	T305	A310T	310	Missense	distal	5	no	4.386	4.457	EPSD	COSMIC	3.716	Up-regulation
CAMK_PIM_PIM3_ST	P35568	IRS1	Q86V86	PIM3	T305	R302L	302	Missense	distal	-3	no	4.386	2.292	EPSD	COSMIC	3.716	Loss
CAMK_PIM_PIM3_ST	P35568	IRS1	Q86V86	PIM3	T305	I308M	308	Missense	distal	3	no	4.386	4.473	EPSD	COSMIC	3.716	Up-regulation
CAMK_PIM_PIM3_ST	P35568	IRS1	Q86V86	PIM3	T305	A310V	310	Missense	distal	5	no	4.386	4.299	EPSD	COSMIC	3.716	Down-regulation
CAMK_PIM_PIM3_ST	P35568	IRS1	Q86V86	PIM3	S307	R301C	301	Missense	distal	-6	no	4.171	4.847	EPSD	COSMIC	3.716	Up-regulation
CAMK_PIM_PIM3_ST	P35568	IRS1	Q86V86	PIM3	S307	E306K	306	Missense	proximal	-1	no	4.171	4.126	EPSD	COSMIC	3.716	Down-regulation
CAMK_PIM_PIM3_ST	P35568	IRS1	Q86V86	PIM3	S307	A310T	310	Missense	distal	3	no	4.171	3.687	EPSD	COSMIC	3.716	Loss
CAMK_PIM_PIM3_ST	P35568	IRS1	Q86V86	PIM3	S307	P313L	313	Missense	distal	6	no	4.171	3.961	EPSD	COSMIC;GDSC;CCLE	3.716	Down-regulation
CAMK_PIM_PIM3_ST	P35568	IRS1	Q86V86	PIM3	S307	R302L	302	Missense	distal	-5	no	4.171	3.733	EPSD	COSMIC	3.716	Down-regulation
CAMK_PIM_PIM3_ST	P35568	IRS1	Q86V86	PIM3	S307	I308M	308	Missense	proximal	1	no	4.171	4.187	EPSD	COSMIC	3.716	Up-regulation
CAMK_PIM_PIM3_ST	P35568	IRS1	Q86V86	PIM3	S307	A310V	310	Missense	distal	3	no	4.171	4.080	EPSD	COSMIC	3.716	Down-regulation
CAMK_PIM_PIM3_ST	P35568	IRS1	Q86V86	PIM3	T309	E306K	306	Missense	distal	-3	no	4.582	3.582	EPSD	COSMIC	3.716	Loss
CAMK_PIM_PIM3_ST	P35568	IRS1	Q86V86	PIM3	T309	A310T	310	Missense	proximal	1	no	4.582	4.567	EPSD	COSMIC	3.716	Down-regulation
CAMK_PIM_PIM3_ST	P35568	IRS1	Q86V86	PIM3	T309	P313L	313	Missense	distal	4	no	4.582	5.063	EPSD	COSMIC;GDSC;CCLE	3.716	Up-regulation
CAMK_PIM_PIM3_ST	P35568	IRS1	Q86V86	PIM3	T309	M316V	316	Missense	distal	7	no	4.582	4.859	EPSD	COSMIC	3.716	Up-regulation
CAMK_PIM_PIM3_ST	P35568	IRS1	Q86V86	PIM3	T309	R302L	302	Missense	distal	-7	no	4.582	5.129	EPSD	COSMIC	3.716	Up-regulation
CAMK_PIM_PIM3_ST	P35568	IRS1	Q86V86	PIM3	T309	M316I	316	Missense	distal	7	no	4.582	4.805	EPSD	COSMIC	3.716	Up-regulation
CAMK_PIM_PIM3_ST	P35568	IRS1	Q86V86	PIM3	T309	I308M	308	Missense	proximal	-1	no	4.582	4.466	EPSD	COSMIC	3.716	Down-regulation
CAMK_PIM_PIM3_ST	P35568	IRS1	Q86V86	PIM3	T309	A310V	310	Missense	proximal	1	no	4.582	4.538	EPSD	COSMIC	3.716	Down-regulation
CAMK_PIM_PIM3_ST	P35568	IRS1	Q86V86	PIM3	S330	R327L	327	Missense	distal	-3	no	4.493	2.399	EPSD	COSMIC	3.716	Loss
CAMK_PIM_PIM3_ST	P35568	IRS1	Q86V86	PIM3	S330	R325H	325	Missense	distal	-5	no	4.493	3.287	EPSD	COSMIC;CCLE	3.716	Loss
CAMK_PIM_PIM3_ST	P35568	IRS1	Q86V86	PIM3	S330	R327C	327	Missense	distal	-3	no	4.493	1.988	EPSD	COSMIC;CCLE	3.716	Loss
CAMK_PIM_PIM3_ST	P35568	IRS1	Q86V86	PIM3	S330	E333K	333	Missense	distal	3	no	4.493	4.669	EPSD	COSMIC	3.716	Up-regulation
CAMK_PIM_PIM3_ST	P35568	IRS1	Q86V86	PIM3	S330	G332R	332	Missense	proximal	2	no	4.493	4.433	EPSD	COSMIC	3.716	Down-regulation
CAMK_PIM_PIM3_ST	P35568	IRS1	Q86V86	PIM3	S330	R325C	325	Missense	distal	-5	no	4.493	3.038	EPSD	COSMIC	3.716	Loss
CAMK_PIM_PIM3_ST	P35568	IRS1	Q86V86	PIM3	S330	F324L	324	Missense	distal	-6	no	4.493	4.277	EPSD	COSMIC	3.716	Down-regulation
CAMK_PIM_PIM3_ST	P35568	IRS1	Q86V86	PIM3	T335	E333K	333	Missense	proximal	-2	no	4.036	4.120	EPSD	COSMIC	3.716	Up-regulation
CAMK_PIM_PIM3_ST	P35568	IRS1	Q86V86	PIM3	T335	S341L	341	Missense	distal	6	no	4.036	3.625	EPSD	COSMIC	3.716	Loss
CAMK_PIM_PIM3_ST	P35568	IRS1	Q86V86	PIM3	T335	G332R	332	Missense	distal	-3	no	4.036	5.715	EPSD	COSMIC	3.716	Up-regulation
CAMK_PIM_PIM3_ST	P35568	IRS1	Q86V86	PIM3	S341	S341L	341	Missense	central	0	yes	4.644	0.000	EPSD	COSMIC	3.716	Loss
CAMK_PIM_PIM3_ST	P35568	IRS1	Q86V86	PIM3	S341	P346S	346	Missense	distal	5	no	4.644	4.558	EPSD	COSMIC	3.716	Down-regulation
CAMK_PIM_PIM3_ST	P35568	IRS1	Q86V86	PIM3	S348	S341L	341	Missense	distal	-7	no	4.321	4.707	EPSD	COSMIC	3.716	Up-regulation
CAMK_PIM_PIM3_ST	P35568	IRS1	Q86V86	PIM3	S348	N352D	352	Missense	distal	4	no	4.321	4.124	EPSD	COSMIC	3.716	Down-regulation
CAMK_PIM_PIM3_ST	P35568	IRS1	Q86V86	PIM3	S348	P349L	349	Missense	proximal	1	no	4.321	4.313	EPSD	COSMIC	3.716	Down-regulation
CAMK_PIM_PIM3_ST	P35568	IRS1	Q86V86	PIM3	S348	P346S	346	Missense	proximal	-2	no	4.321	4.192	EPSD	COSMIC	3.716	Down-regulation
CAMK_PIM_PIM3_ST	P35568	IRS1	Q86V86	PIM3	T397	S398G	398	Missense	proximal	1	no	4.342	4.486	EPSD	COSMIC	3.716	Up-regulation
CAMK_PIM_PIM3_ST	P35568	IRS1	Q86V86	PIM3	T397	G401D	401	Missense	distal	4	no	4.342	4.473	EPSD	COSMIC	3.716	Up-regulation
CAMK_PIM_PIM3_ST	P35568	IRS1	Q86V86	PIM3	T397	T403S	403	Missense	distal	6	no	4.342	4.364	EPSD	COSMIC	3.716	Up-regulation
CAMK_PIM_PIM3_ST	P35568	IRS1	Q86V86	PIM3	T397	H400Q	400	Missense	distal	3	no	4.342	4.041	EPSD	COSMIC	3.716	Down-regulation
CAMK_PIM_PIM3_ST	P35568	IRS1	Q86V86	PIM3	T397	S395I	395	Missense	proximal	-2	no	4.342	4.488	EPSD	COSMIC;GDSC;CCLE	3.716	Up-regulation
CAMK_PIM_PIM3_ST	P35568	IRS1	Q86V86	PIM3	S398	S398G	398	Missense	central	0	yes	4.113	0.000	EPSD	COSMIC	3.716	Loss
CAMK_PIM_PIM3_ST	P35568	IRS1	Q86V86	PIM3	S398	G401D	401	Missense	distal	3	no	4.113	4.409	EPSD	COSMIC	3.716	Up-regulation
CAMK_PIM_PIM3_ST	P35568	IRS1	Q86V86	PIM3	S398	T403S	403	Missense	distal	5	no	4.113	3.933	EPSD	COSMIC	3.716	Down-regulation
CAMK_PIM_PIM3_ST	P35568	IRS1	Q86V86	PIM3	S398	H400Q	400	Missense	proximal	2	no	4.113	4.044	EPSD	COSMIC	3.716	Down-regulation
CAMK_PIM_PIM3_ST	P35568	IRS1	Q86V86	PIM3	S398	S395I	395	Missense	distal	-3	no	4.113	2.519	EPSD	COSMIC;GDSC;CCLE	3.716	Loss
CAMK_PIM_PIM3_ST	P35568	IRS1	Q86V86	PIM3	T403	S398G	398	Missense	distal	-5	no	4.250	3.920	EPSD	COSMIC	3.716	Down-regulation
CAMK_PIM_PIM3_ST	P35568	IRS1	Q86V86	PIM3	T403	G401D	401	Missense	proximal	-2	no	4.250	4.100	EPSD	COSMIC	3.716	Down-regulation
CAMK_PIM_PIM3_ST	P35568	IRS1	Q86V86	PIM3	T403	H400Q	400	Missense	distal	-3	no	4.250	4.199	EPSD	COSMIC	3.716	Down-regulation
CAMK_PIM_PIM3_ST	P35568	IRS1	Q86V86	PIM3	S415	S415L	415	Missense	central	0	yes	4.182	0.000	EPSD	COSMIC	3.716	Loss
CAMK_PIM_PIM3_ST	P35568	IRS1	Q86V86	PIM3	S415	G418V	418	Missense	distal	3	no	4.182	4.249	EPSD	COSMIC;GDSC;CCLE	3.716	Up-regulation
CAMK_PIM_PIM3_ST	P35568	IRS1	Q86V86	PIM3	S415	D422N	422	Missense	distal	7	no	4.182	3.933	EPSD	COSMIC	3.716	Down-regulation
CAMK_PIM_PIM3_ST	P35568	IRS1	Q86V86	PIM3	S433	P435L	435	Missense	proximal	2	no	3.861	3.982	EPSD	COSMIC	3.716	Up-regulation
CAMK_PIM_PIM3_ST	P35568	IRS1	Q86V86	PIM3	S433	R439Q	439	Missense	distal	6	no	3.861	3.771	EPSD	COSMIC	3.716	Down-regulation
CAMK_PIM_PIM3_ST	P35568	IRS1	Q86V86	PIM3	S433	S434G	434	Missense	proximal	1	no	3.861	4.004	EPSD	COSMIC	3.716	Up-regulation
CAMK_PIM_PIM3_ST	P35568	IRS1	Q86V86	PIM3	S433	P435F	435	Missense	proximal	2	no	3.861	3.944	EPSD	COSMIC	3.716	Up-regulation
CAMK_PIM_PIM3_ST	P35568	IRS1	Q86V86	PIM3	S444	G451C	451	Missense	distal	7	no	3.688	3.746	EPSD	COSMIC	3.716	Gain
CAMK_PIM_PIM3_ST	P35568	IRS1	Q86V86	PIM3	S444	D448E	448	Missense	distal	4	no	3.688	3.790	EPSD	COSMIC	3.716	Gain
CAMK_PIM_PIM3_ST	P35568	IRS1	Q86V86	PIM3	S444	S441F	441	Missense	distal	-3	no	3.688	3.781	EPSD	COSMIC	3.716	Gain
CAMK_PIM_PIM3_ST	P35568	IRS1	Q86V86	PIM3	S444	P447L	447	Missense	distal	3	no	3.688	3.736	EPSD	COSMIC	3.716	Gain
CAMK_PIM_PIM3_ST	P35568	IRS1	Q86V86	PIM3	S444	S449P	449	Missense	distal	5	no	3.688	3.774	EPSD	COSMIC	3.716	Gain
CAMK_PIM_PIM3_ST	P35568	IRS1	Q86V86	PIM3	T525	T530A	530	Missense	distal	5	no	4.253	4.181	EPSD	COSMIC	3.716	Down-regulation
CAMK_PIM_PIM3_ST	P35568	IRS1	Q86V86	PIM3	T525	R520L	520	Missense	distal	-5	no	4.253	3.815	EPSD	COSMIC	3.716	Down-regulation
CAMK_PIM_PIM3_ST	P35568	IRS1	Q86V86	PIM3	T525	F521I	521	Missense	distal	-4	no	4.253	3.936	EPSD	COSMIC	3.716	Down-regulation
CAMK_PIM_PIM3_ST	P35568	IRS1	Q86V86	PIM3	T525	H526Y	526	Missense	proximal	1	no	4.253	4.318	EPSD	COSMIC	3.716	Up-regulation
CAMK_PIM_PIM3_ST	P35568	IRS1	Q86V86	PIM3	T525	G529D	529	Missense	distal	4	no	4.253	4.383	EPSD	COSMIC	3.716	Up-regulation
CAMK_PIM_PIM3_ST	P35568	IRS1	Q86V86	PIM3	S527	T530A	530	Missense	distal	3	no	3.958	4.441	EPSD	COSMIC	3.716	Up-regulation
CAMK_PIM_PIM3_ST	P35568	IRS1	Q86V86	PIM3	S527	R520L	520	Missense	distal	-7	no	3.958	4.505	EPSD	COSMIC	3.716	Up-regulation
CAMK_PIM_PIM3_ST	P35568	IRS1	Q86V86	PIM3	S527	T533I	533	Missense	distal	6	no	3.958	3.775	EPSD	COSMIC	3.716	Down-regulation
CAMK_PIM_PIM3_ST	P35568	IRS1	Q86V86	PIM3	S527	F521I	521	Missense	distal	-6	no	3.958	4.078	EPSD	COSMIC	3.716	Up-regulation
CAMK_PIM_PIM3_ST	P35568	IRS1	Q86V86	PIM3	S527	H526Y	526	Missense	proximal	-1	no	3.958	4.051	EPSD	COSMIC	3.716	Up-regulation
CAMK_PIM_PIM3_ST	P35568	IRS1	Q86V86	PIM3	S527	G529D	529	Missense	proximal	2	no	3.958	3.890	EPSD	COSMIC	3.716	Down-regulation
CAMK_PIM_PIM3_ST	P35568	IRS1	Q86V86	PIM3	T579	E584K	584	Missense	distal	5	no	4.333	4.364	EPSD	COSMIC	3.716	Up-regulation
CAMK_PIM_PIM3_ST	P35568	IRS1	Q86V86	PIM3	T579	P578S	578	Missense	proximal	-1	no	4.333	4.213	EPSD	COSMIC	3.716	Down-regulation
CAMK_PIM_PIM3_ST	P35568	IRS1	Q86V86	PIM3	T579	F576L	576	Missense	distal	-3	no	4.333	3.370	EPSD	COSMIC	3.716	Loss
CAMK_PIM_PIM3_ST	P35568	IRS1	Q86V86	PIM3	S603	H598R	598	Missense	distal	-5	no	4.669	5.875	EPSD	COSMIC	3.716	Up-regulation
CAMK_PIM_PIM3_ST	P35568	IRS1	Q86V86	PIM3	S603	G596E	596	Missense	distal	-7	no	4.669	4.513	EPSD	COSMIC	3.716	Down-regulation
CAMK_PIM_PIM3_ST	P35568	IRS1	Q86V86	PIM3	S603	H599Y	599	Missense	distal	-4	no	4.669	4.609	EPSD	COSMIC	3.716	Down-regulation
CAMK_PIM_PIM3_ST	P35568	IRS1	Q86V86	PIM3	S603	H599Q	599	Missense	distal	-4	no	4.669	4.855	EPSD	COSMIC	3.716	Up-regulation
CAMK_PIM_PIM3_ST	P35568	IRS1	Q86V86	PIM3	S636	A642T	642	Missense	distal	6	no	3.533	3.848	EPSD	COSMIC	3.716	Gain
CAMK_PIM_PIM3_ST	P35568	IRS1	Q86V86	PIM3	T793	S792F	792	Missense	proximal	-1	no	4.369	4.330	EPSD	COSMIC	3.716	Down-regulation
CAMK_PIM_PIM3_ST	P35568	IRS1	Q86V86	PIM3	T793	R790C	790	Missense	distal	-3	no	4.369	1.864	EPSD	COSMIC	3.716	Loss
CAMK_PIM_PIM3_ST	P35568	IRS1	Q86V86	PIM3	T793	Q787R	787	Missense	distal	-6	no	4.369	4.175	EPSD	COSMIC	3.716	Down-regulation
CAMK_PIM_PIM3_ST	P35568	IRS1	Q86V86	PIM3	S794	S792F	792	Missense	proximal	-2	no	4.487	4.804	EPSD	COSMIC	3.716	Up-regulation
CAMK_PIM_PIM3_ST	P35568	IRS1	Q86V86	PIM3	S794	R790C	790	Missense	distal	-4	no	4.487	5.182	EPSD	COSMIC	3.716	Up-regulation
CAMK_PIM_PIM3_ST	P35568	IRS1	Q86V86	PIM3	S794	A801V	801	Missense	distal	7	no	4.487	4.640	EPSD	COSMIC	3.716	Up-regulation
CAMK_PIM_PIM3_ST	P35568	IRS1	Q86V86	PIM3	S794	Q787R	787	Missense	distal	-7	no	4.487	4.198	EPSD	COSMIC	3.716	Down-regulation
CAMK_PIM_PIM3_ST	P35568	IRS1	Q86V86	PIM3	S795	S792F	792	Missense	distal	-3	no	4.451	4.544	EPSD	COSMIC	3.716	Up-regulation
CAMK_PIM_PIM3_ST	P35568	IRS1	Q86V86	PIM3	S795	R790C	790	Missense	distal	-5	no	4.451	2.996	EPSD	COSMIC	3.716	Loss
CAMK_PIM_PIM3_ST	P35568	IRS1	Q86V86	PIM3	S795	A801V	801	Missense	distal	6	no	4.451	4.418	EPSD	COSMIC	3.716	Down-regulation
CAMK_PIM_PIM3_ST	P35568	IRS1	Q86V86	PIM3	T859	T859M	859	Missense	central	0	yes	4.638	0.000	EPSD	COSMIC	3.716	Loss
CAMK_PIM_PIM3_ST	P35568	IRS1	Q86V86	PIM3	T859	L855P	855	Missense	distal	-4	no	4.638	4.184	EPSD	COSMIC	3.716	Down-regulation
CAMK_PIM_PIM3_ST	P35568	IRS1	Q86V86	PIM3	T859	R857Q	857	Missense	proximal	-2	no	4.638	4.805	EPSD	COSMIC	3.716	Up-regulation
CAMK_PIM_PIM3_ST	P35568	IRS1	Q86V86	PIM3	T859	G864W	864	Missense	distal	5	no	4.638	4.472	EPSD	COSMIC	3.716	Down-regulation
CAMK_PIM_PIM3_ST	P35568	IRS1	Q86V86	PIM3	T859	R854L	854	Missense	distal	-5	no	4.638	4.200	EPSD	COSMIC	3.716	Down-regulation
CAMK_PIM_PIM3_ST	P35568	IRS1	Q86V86	PIM3	T859	P858H	858	Missense	proximal	-1	no	4.638	4.640	EPSD	COSMIC	3.716	Up-regulation
CAMK_PIM_PIM3_ST	P35568	IRS1	Q86V86	PIM3	T870	G864W	864	Missense	distal	-6	no	4.657	4.858	EPSD	COSMIC	3.716	Up-regulation
CAMK_PIM_PIM3_ST	P35568	IRS1	Q86V86	PIM3	T870	P872T	872	Missense	proximal	2	no	4.657	4.677	EPSD	COSMIC	3.716	Up-regulation
CAMK_PIM_PIM3_ST	P35568	IRS1	Q86V86	PIM3	T938	R932I	932	Missense	distal	-6	no	3.427	3.883	EPSD	COSMIC	3.716	Gain
CAMK_PIM_PIM3_ST	P35568	IRS1	Q86V86	PIM3	S1101	R1097W	1097	Missense	distal	-4	no	8.897	9.826	PhosphoSitePlus	COSMIC	3.716	Up-regulation
CAMK_PIM_PIM3_ST	P35568	IRS1	Q86V86	PIM3	S1101	E1102K	1102	Missense	proximal	1	no	8.897	8.929	PhosphoSitePlus	COSMIC	3.716	Up-regulation
CAMK_PIM_PIM3_ST	P35568	IRS1	Q86V86	PIM3	S1105	E1102K	1102	Missense	distal	-3	no	4.113	3.114	EPSD	COSMIC	3.716	Loss
TK_Src_SrcB_LCK_Y	Q9NP31	SH2D2A	P06239	LCK	Y260	R266Q	266	Missense	distal	6	no	5.536	5.937	EPSD;PhosphoSitePlus	COSMIC	5.050	Up-regulation
TK_Src_SrcB_LCK_Y	Q9NP31	SH2D2A	P06239	LCK	Y280	E285K	285	Missense	distal	5	no	7.647	7.751	EPSD;PhosphoSitePlus	COSMIC	5.050	Up-regulation
TK_Src_SrcB_LCK_Y	Q9NP31	SH2D2A	P06239	LCK	Y280	P278H	278	Missense	proximal	-2	no	7.647	7.121	EPSD;PhosphoSitePlus	COSMIC	5.050	Down-regulation
TK_Src_SrcB_LCK_Y	Q9NP31	SH2D2A	P06239	LCK	Y280	P278L	278	Missense	proximal	-2	no	7.647	6.660	EPSD;PhosphoSitePlus	COSMIC	5.050	Down-regulation
TK_Src_SrcB_LCK_Y	Q9NP31	SH2D2A	P06239	LCK	Y280	E282K	282	Missense	proximal	2	no	7.647	7.621	EPSD;PhosphoSitePlus	COSMIC	5.050	Down-regulation
TK_Src_SrcB_LCK_Y	Q9NP31	SH2D2A	P06239	LCK	Y280	K274T	274	Missense	distal	-6	no	7.647	7.870	EPSD;PhosphoSitePlus	COSMIC	5.050	Up-regulation
TK_Src_SrcB_LCK_Y	Q9NP31	SH2D2A	P06239	LCK	Y280	I287T	287	Missense	distal	7	no	7.647	7.790	EPSD;PhosphoSitePlus	COSMIC	5.050	Up-regulation
TK_Src_SrcB_LCK_Y	Q9NP31	SH2D2A	P06239	LCK	Y290	R294P	294	Missense	distal	4	no	5.581	5.261	PhosphoSitePlus;EPSD	COSMIC	5.050	Down-regulation
TK_Src_SrcB_LCK_Y	Q9NP31	SH2D2A	P06239	LCK	Y290	E285K	285	Missense	distal	-5	no	5.581	4.921	PhosphoSitePlus;EPSD	COSMIC	5.050	Loss
TK_Src_SrcB_LCK_Y	Q9NP31	SH2D2A	P06239	LCK	Y290	R294W	294	Missense	distal	4	no	5.581	4.574	PhosphoSitePlus;EPSD	COSMIC;GDSC;CCLE	5.050	Loss
TK_Src_SrcB_LCK_Y	Q9NP31	SH2D2A	P06239	LCK	Y290	I287T	287	Missense	distal	-3	no	5.581	6.300	PhosphoSitePlus;EPSD	COSMIC	5.050	Up-regulation
TK_Src_SrcB_LCK_Y	Q9NP31	SH2D2A	P06239	LCK	Y290	R294L	294	Missense	distal	4	no	5.581	4.845	PhosphoSitePlus;EPSD	COSMIC	5.050	Loss
TK_Src_SrcB_LCK_Y	Q9NP31	SH2D2A	P06239	LCK	Y290	A288D	288	Missense	proximal	-2	no	5.581	6.637	PhosphoSitePlus;EPSD	COSMIC	5.050	Up-regulation
TK_Src_SrcB_LCK_Y	Q9NP31	SH2D2A	P06239	LCK	Y290	R294Q	294	Missense	distal	4	no	5.581	5.469	PhosphoSitePlus;EPSD	COSMIC	5.050	Down-regulation
TK_Src_SrcB_LCK_Y	Q9NP31	SH2D2A	P06239	LCK	Y290	A291S	291	Missense	proximal	1	no	5.581	5.646	PhosphoSitePlus;EPSD	COSMIC	5.050	Up-regulation
TK_Src_SrcB_LCK_Y	Q9NP31	SH2D2A	P06239	LCK	Y305	G298V	298	Missense	distal	-7	no	7.758	7.783	EPSD;PhosphoSitePlus	COSMIC	5.050	Up-regulation
TK_Src_SrcB_LCK_Y	Q9NP31	SH2D2A	P06239	LCK	Y305	G298E	298	Missense	distal	-7	no	7.758	8.247	EPSD;PhosphoSitePlus	COSMIC	5.050	Up-regulation
TK_Src_SrcB_LCK_Y	P06127	CD5	P06239	LCK	Y453	D450N	450	Missense	distal	-3	no	8.886	7.911	PhosphoSitePlus;EPSD	COSMIC	5.050	Down-regulation
TK_Src_SrcB_LCK_Y	P06127	CD5	P06239	LCK	Y465	L468V	468	Missense	distal	3	no	5.597	5.399	EPSD	COSMIC	5.050	Down-regulation
TK_Src_SrcB_LCK_Y	P06127	CD5	P06239	LCK	Y465	L462M	462	Missense	distal	-3	no	5.597	5.825	EPSD	COSMIC;GDSC;CCLE	5.050	Up-regulation
TK_Src_SrcB_LCK_Y	Q9H204	MED28	P06239	LCK	Y64	D69N	69	Missense	distal	5	no	6.252	6.323	PhosphoSitePlus	COSMIC	5.050	Up-regulation
TK_Src_SrcB_LCK_Y	Q9H204	MED28	P06239	LCK	Y64	D69E	69	Missense	distal	5	no	6.252	6.230	PhosphoSitePlus	COSMIC	5.050	Down-regulation
TK_Src_SrcB_LCK_Y	P16885	PLCG2	P06239	LCK	Y743	E741D	741	Missense	proximal	-2	no	5.745	5.994	EPSD	COSMIC	5.050	Up-regulation
TK_Src_SrcB_LCK_Y	P16885	PLCG2	P06239	LCK	Y743	R742H	742	Missense	proximal	-1	no	5.745	6.750	EPSD	COSMIC;CCLE	5.050	Up-regulation
TK_Src_SrcB_LCK_Y	P16885	PLCG2	P06239	LCK	Y743	R742S	742	Missense	proximal	-1	no	5.745	5.825	EPSD	COSMIC	5.050	Up-regulation
TK_Src_SrcB_LCK_Y	P16885	PLCG2	P06239	LCK	Y753	M758I	758	Missense	distal	5	no	5.520	5.619	PhosphoSitePlus;EPSD	COSMIC	5.050	Up-regulation
TK_Src_SrcB_LCK_Y	P16885	PLCG2	P06239	LCK	Y753	S751F	751	Missense	proximal	-2	no	5.520	4.953	PhosphoSitePlus;EPSD	COSMIC	5.050	Loss
TK_Src_SrcB_LCK_Y	P16885	PLCG2	P06239	LCK	Y759	P762L	762	Missense	distal	3	no	5.707	6.422	EPSD;PhosphoSitePlus	COSMIC	5.050	Up-regulation
TK_Src_SrcB_LCK_Y	P16885	PLCG2	P06239	LCK	Y759	M758I	758	Missense	proximal	-1	no	5.707	6.588	EPSD;PhosphoSitePlus	COSMIC	5.050	Up-regulation
TK_Src_SrcB_LCK_Y	P16885	PLCG2	P06239	LCK	Y858	N859S	859	Missense	proximal	1	no	6.096	5.663	EPSD	COSMIC	5.050	Down-regulation
TK_Src_SrcB_LCK_Y	P16885	PLCG2	P06239	LCK	Y858	Q865H	865	Missense	distal	7	no	6.096	6.019	EPSD	COSMIC	5.050	Down-regulation
TK_Src_SrcB_LCK_Y	P16885	PLCG2	P06239	LCK	Y1197	E1191D	1191	Missense	distal	-6	no	6.477	5.980	EPSD;PhosphoSitePlus	COSMIC	5.050	Down-regulation
TK_Src_SrcB_LCK_Y	P16885	PLCG2	P06239	LCK	Y1197	L1203P	1203	Missense	distal	6	no	6.477	6.366	EPSD;PhosphoSitePlus	COSMIC	5.050	Down-regulation
TK_Src_SrcB_LCK_Y	P29353	SHC1	P06239	LCK	Y349	E343K	343	Missense	distal	-6	no	8.905	8.024	EPSD	COSMIC	5.050	Down-regulation
TK_Src_SrcB_LCK_Y	P29353	SHC1	P06239	LCK	Y349	N351Y	351	Missense	proximal	2	no	8.905	8.312	EPSD	COSMIC	5.050	Down-regulation
TK_Src_SrcB_LCK_Y	P29353	SHC1	P06239	LCK	Y349	P354L	354	Missense	distal	5	no	8.905	9.020	EPSD	COSMIC	5.050	Up-regulation
TK_Src_SrcB_LCK_Y	P29353	SHC1	P06239	LCK	Y349	E343D	343	Missense	distal	-6	no	8.905	8.408	EPSD	COSMIC	5.050	Down-regulation
TK_Src_SrcB_LCK_Y	P29353	SHC1	P06239	LCK	Y350	E343K	343	Missense	distal	-7	no	7.492	7.072	EPSD	COSMIC	5.050	Down-regulation
TK_Src_SrcB_LCK_Y	P29353	SHC1	P06239	LCK	Y350	E357D	357	Missense	distal	7	no	7.492	7.447	EPSD	COSMIC;GDSC	5.050	Down-regulation
TK_Src_SrcB_LCK_Y	P29353	SHC1	P06239	LCK	Y350	N351Y	351	Missense	proximal	1	no	7.492	7.267	EPSD	COSMIC	5.050	Down-regulation
TK_Src_SrcB_LCK_Y	P29353	SHC1	P06239	LCK	Y350	P354L	354	Missense	distal	4	no	7.492	7.077	EPSD	COSMIC	5.050	Down-regulation
TK_Src_SrcB_LCK_Y	P29353	SHC1	P06239	LCK	Y350	E343D	343	Missense	distal	-7	no	7.492	7.144	EPSD	COSMIC	5.050	Down-regulation
TK_Src_SrcB_LCK_Y	P29353	SHC1	P06239	LCK	Y427	V430I	430	Missense	distal	3	no	7.761	7.814	EPSD	COSMIC	5.050	Up-regulation
TK_Src_SrcB_LCK_Y	P29353	SHC1	P06239	LCK	Y427	S426C	426	Missense	proximal	-1	no	7.761	7.631	EPSD	COSMIC	5.050	Down-regulation
TK_Src_SrcB_LCK_Y	P29353	SHC1	P06239	LCK	Y427	S426P	426	Missense	proximal	-1	no	7.761	8.137	EPSD	COSMIC	5.050	Up-regulation
TK_Src_SrcB_LCK_Y	P20963	CD247	P06239	LCK	Y72	R79Q	79	Missense	distal	7	no	6.145	6.228	EPSD	COSMIC	5.050	Up-regulation
TK_Src_SrcB_LCK_Y	P20963	CD247	P06239	LCK	Y72	G67D	67	Missense	distal	-5	no	6.145	6.276	EPSD	COSMIC	5.050	Up-regulation
TK_Src_SrcB_LCK_Y	P20963	CD247	P06239	LCK	Y83	R79Q	79	Missense	distal	-4	no	5.558	5.906	EPSD	COSMIC	5.050	Up-regulation
TK_Src_SrcB_LCK_Y	P20963	CD247	P06239	LCK	Y83	D84G	84	Missense	proximal	1	no	5.558	4.366	EPSD	COSMIC;GDSC	5.050	Loss
TK_Src_SrcB_LCK_Y	P20963	CD247	P06239	LCK	Y123	A120V	120	Missense	distal	-3	no	7.621	7.888	EPSD	COSMIC;GDSC;CCLE	5.050	Up-regulation
TK_Src_SrcB_LCK_Y	P20963	CD247	P06239	LCK	Y123	A122G	122	Missense	proximal	-1	no	7.621	7.266	EPSD	COSMIC	5.050	Down-regulation
TK_Src_SrcB_LCK_Y	P20963	CD247	P06239	LCK	Y123	E121K	121	Missense	proximal	-2	no	7.621	7.051	EPSD	COSMIC	5.050	Down-regulation
TK_Src_SrcB_LCK_Y	P20963	CD247	P06239	LCK	Y142	S146G	146	Missense	distal	4	no	8.002	7.648	PhosphoSitePlus	COSMIC	5.050	Down-regulation
TK_Src_SrcB_LCK_Y	P20963	CD247	P06239	LCK	Y153	S146G	146	Missense	distal	-7	no	7.641	7.365	EPSD	COSMIC	5.050	Down-regulation
TK_Src_SrcB_LCK_Y	P20963	CD247	P06239	LCK	Y153	D151N	151	Missense	proximal	-2	no	7.641	7.046	EPSD	COSMIC	5.050	Down-regulation
TK_Src_SrcB_LCK_Y	Q9BWW4	SSBP3	P06239	LCK	Y23	E26K	26	Missense	distal	3	no	6.465	5.537	EPSD;PhosphoSitePlus	COSMIC	5.050	Down-regulation
TK_Src_SrcB_LCK_Y	Q9BWW4	SSBP3	P06239	LCK	Y23	E18K	18	Missense	distal	-5	no	6.465	5.805	EPSD;PhosphoSitePlus	COSMIC	5.050	Down-regulation
TK_Src_SrcB_LCK_Y	Q9BWW4	SSBP3	P06239	LCK	Y25	E26K	26	Missense	proximal	1	no	5.842	4.893	PhosphoSitePlus;EPSD	COSMIC	5.050	Loss
TK_Src_SrcB_LCK_Y	Q9BWW4	SSBP3	P06239	LCK	Y25	E18K	18	Missense	distal	-7	no	5.842	5.422	PhosphoSitePlus;EPSD	COSMIC	5.050	Down-regulation
TK_Src_SrcB_LCK_Y	P52757	CHN2	P06239	LCK	Y21	P24S	24	Missense	distal	3	no	4.952	5.292	EPSD	COSMIC	5.050	Gain
TK_Src_SrcB_LCK_Y	P52757	CHN2	P06239	LCK	Y153	T149I	149	Missense	distal	-4	no	6.775	6.390	PhosphoSitePlus	COSMIC	5.050	Down-regulation
TK_Src_SrcB_LCK_Y	P52757	CHN2	P06239	LCK	Y153	P151T	151	Missense	proximal	-2	no	6.775	6.640	PhosphoSitePlus	COSMIC	5.050	Down-regulation
TK_Src_SrcB_LCK_Y	P43403	ZAP70	P06239	LCK	Y69	T68M	68	Missense	proximal	-1	no	6.106	6.303	EPSD;PhosphoSitePlus	COSMIC	5.050	Up-regulation
TK_Src_SrcB_LCK_Y	P43403	ZAP70	P06239	LCK	Y69	L65V	65	Missense	distal	-4	no	6.106	6.677	EPSD;PhosphoSitePlus	COSMIC	5.050	Up-regulation
TK_Src_SrcB_LCK_Y	P43403	ZAP70	P06239	LCK	Y69	E62K	62	Missense	distal	-7	no	6.106	5.686	EPSD;PhosphoSitePlus	COSMIC;CCLE	5.050	Down-regulation
TK_Src_SrcB_LCK_Y	P43403	ZAP70	P06239	LCK	Y69	Q64L	64	Missense	distal	-5	no	6.106	6.227	EPSD;PhosphoSitePlus	COSMIC;GDSC	5.050	Up-regulation
TK_Src_SrcB_LCK_Y	P43403	ZAP70	P06239	LCK	Y69	K75N	75	Missense	distal	6	no	6.106	6.045	EPSD;PhosphoSitePlus	COSMIC	5.050	Down-regulation
TK_Src_SrcB_LCK_Y	P43403	ZAP70	P06239	LCK	Y69	R63H	63	Missense	distal	-6	no	6.106	6.168	EPSD;PhosphoSitePlus	COSMIC	5.050	Up-regulation
TK_Src_SrcB_LCK_Y	P43403	ZAP70	P06239	LCK	Y69	G74S	74	Missense	distal	5	no	6.106	6.021	EPSD;PhosphoSitePlus	COSMIC	5.050	Down-regulation
TK_Src_SrcB_LCK_Y	P43403	ZAP70	P06239	LCK	Y126	R119Q	119	Missense	distal	-7	no	6.232	6.093	EPSD;PhosphoSitePlus	COSMIC	5.050	Down-regulation
TK_Src_SrcB_LCK_Y	P43403	ZAP70	P06239	LCK	Y178	L177F	177	Missense	proximal	-1	no	7.005	6.199	EPSD;PhosphoSitePlus	COSMIC	5.050	Down-regulation
TK_Src_SrcB_LCK_Y	P43403	ZAP70	P06239	LCK	Y178	R175H	175	Missense	distal	-3	no	7.005	5.889	EPSD;PhosphoSitePlus	COSMIC	5.050	Down-regulation
TK_Src_SrcB_LCK_Y	P43403	ZAP70	P06239	LCK	Y178	A173V	173	Missense	distal	-5	no	7.005	6.624	EPSD;PhosphoSitePlus	COSMIC	5.050	Down-regulation
TK_Src_SrcB_LCK_Y	P43403	ZAP70	P06239	LCK	Y178	D184G	184	Missense	distal	6	no	7.005	7.282	EPSD;PhosphoSitePlus	COSMIC	5.050	Up-regulation
TK_Src_SrcB_LCK_Y	P43403	ZAP70	P06239	LCK	Y178	A173T	173	Missense	distal	-5	no	7.005	6.882	EPSD;PhosphoSitePlus	COSMIC	5.050	Down-regulation
TK_Src_SrcB_LCK_Y	P43403	ZAP70	P06239	LCK	Y292	R298C	298	Missense	distal	6	no	6.681	7.920	EPSD;PhosphoSitePlus	COSMIC	5.050	Up-regulation
TK_Src_SrcB_LCK_Y	P43403	ZAP70	P06239	LCK	Y292	D285N	285	Missense	distal	-7	no	6.681	6.655	EPSD;PhosphoSitePlus	COSMIC;GDSC;CCLE	5.050	Down-regulation
TK_Src_SrcB_LCK_Y	P43403	ZAP70	P06239	LCK	Y292	R298H	298	Missense	distal	6	no	6.681	6.558	EPSD;PhosphoSitePlus	COSMIC	5.050	Down-regulation
TK_Src_SrcB_LCK_Y	P43403	ZAP70	P06239	LCK	Y315	T312M	312	Missense	distal	-3	no	7.852	6.970	PhosphoSitePlus;EPSD	COSMIC	5.050	Down-regulation
TK_Src_SrcB_LCK_Y	P43403	ZAP70	P06239	LCK	Y319	T312M	312	Missense	distal	-7	no	8.248	8.510	EPSD;PhosphoSitePlus	COSMIC	5.050	Up-regulation
TK_Src_SrcB_LCK_Y	P43403	ZAP70	P06239	LCK	Y492	A495V	495	Missense	distal	3	no	8.350	8.204	EPSD;PhosphoSitePlus	COSMIC	5.050	Down-regulation
TK_Src_SrcB_LCK_Y	P43403	ZAP70	P06239	LCK	Y492	D490N	490	Missense	proximal	-2	no	8.350	7.755	EPSD;PhosphoSitePlus	COSMIC	5.050	Down-regulation
TK_Src_SrcB_LCK_Y	P43403	ZAP70	P06239	LCK	Y493	A495V	495	Missense	proximal	2	no	6.652	5.351	EPSD;PhosphoSitePlus	COSMIC	5.050	Down-regulation
TK_Src_SrcB_LCK_Y	P43403	ZAP70	P06239	LCK	Y493	D490N	490	Missense	distal	-3	no	6.652	5.676	EPSD;PhosphoSitePlus	COSMIC	5.050	Down-regulation
TK_Src_SrcB_LCK_Y	P43403	ZAP70	P06239	LCK	Y493	K500R	500	Missense	distal	7	no	6.652	6.728	EPSD;PhosphoSitePlus	COSMIC	5.050	Up-regulation
TK_Src_SrcB_LCK_Y	P43403	ZAP70	P06239	LCK	Y569	E567A	567	Missense	proximal	-2	no	7.233	6.426	EPSD	COSMIC	5.050	Down-regulation
TK_Src_SrcB_LCK_Y	P43403	ZAP70	P06239	LCK	Y569	P566L	566	Missense	distal	-3	no	7.233	6.999	EPSD	COSMIC	5.050	Down-regulation
TK_Src_SrcB_LCK_Y	P20138	CD33	P06239	LCK	Y340	N344K	344	Missense	distal	4	no	6.770	6.934	PhosphoSitePlus	COSMIC	5.050	Up-regulation
TK_Src_SrcB_LCK_Y	P20138	CD33	P06239	LCK	Y340	S342F	342	Missense	proximal	2	no	6.770	5.934	PhosphoSitePlus	COSMIC	5.050	Down-regulation
TK_Src_SrcB_LCK_Y	P20138	CD33	P06239	LCK	Y340	E336D	336	Missense	distal	-4	no	6.770	6.694	PhosphoSitePlus	COSMIC	5.050	Down-regulation
TK_Src_SrcB_LCK_Y	Q8IVM0	CCDC50	P06239	LCK	Y217	R223W	223	Missense	distal	6	no	7.910	8.770	EPSD;PhosphoSitePlus	COSMIC	5.050	Up-regulation
TK_Src_SrcB_LCK_Y	Q8IVM0	CCDC50	P06239	LCK	Y217	E224D	224	Missense	distal	7	no	7.910	7.864	EPSD;PhosphoSitePlus	COSMIC;CCLE	5.050	Down-regulation
TK_Src_SrcB_LCK_Y	Q8IVM0	CCDC50	P06239	LCK	Y217	K218R	218	Missense	proximal	1	no	7.910	7.933	EPSD;PhosphoSitePlus	COSMIC	5.050	Up-regulation
TK_Src_SrcB_LCK_Y	Q8IVM0	CCDC50	P06239	LCK	Y217	R223Q	223	Missense	distal	6	no	7.910	8.311	EPSD;PhosphoSitePlus	COSMIC	5.050	Up-regulation
TK_Src_SrcB_LCK_Y	Q8IVM0	CCDC50	P06239	LCK	Y279	D278G	278	Missense	proximal	-1	no	10.434	8.613	EPSD;PhosphoSitePlus	COSMIC	5.050	Down-regulation
TK_Src_SrcB_LCK_Y	Q8IVM0	CCDC50	P06239	LCK	Y279	T283A	283	Missense	distal	4	no	10.434	10.817	EPSD;PhosphoSitePlus	COSMIC;CCLE	5.050	Up-regulation
TK_Src_SrcB_LCK_Y	Q8IVM0	CCDC50	P06239	LCK	Y279	A277V	277	Missense	proximal	-2	no	10.434	9.999	EPSD;PhosphoSitePlus	COSMIC	5.050	Down-regulation
TK_Src_SrcB_LCK_Y	P06239	LCK	P06239	LCK	Y394	L388F	388	Missense	distal	-6	no	8.757	8.502	EPSD;PhosphoSitePlus	COSMIC	5.050	Down-regulation
TK_Src_SrcB_LCK_Y	P06239	LCK	P06239	LCK	Y394	D391N	391	Missense	distal	-3	no	8.757	7.782	EPSD;PhosphoSitePlus	COSMIC	5.050	Down-regulation
TK_Src_SrcB_LCK_Y	P06239	LCK	P06239	LCK	Y394	A396V	396	Missense	proximal	2	no	8.757	7.457	EPSD;PhosphoSitePlus	COSMIC;GDSC;CCLE	5.050	Down-regulation
TK_Src_SrcB_LCK_Y	P06239	LCK	P06239	LCK	Y394	L388I	388	Missense	distal	-6	no	8.757	8.084	EPSD;PhosphoSitePlus	COSMIC	5.050	Down-regulation
TK_Src_SrcB_LCK_Y	P06239	LCK	P06239	LCK	Y394	R387C	387	Missense	distal	-7	no	8.757	8.072	EPSD;PhosphoSitePlus	COSMIC	5.050	Down-regulation
TK_Src_SrcB_LCK_Y	P06239	LCK	P06239	LCK	Y505	G503D	503	Missense	proximal	-2	no	6.755	7.687	PhosphoSitePlus;EPSD	COSMIC	5.050	Up-regulation
TK_Src_SrcB_LCK_Y	P06239	LCK	P06239	LCK	Y505	A500T	500	Missense	distal	-5	no	6.755	6.632	PhosphoSitePlus;EPSD	COSMIC;GDSC;CCLE	5.050	Down-regulation
TK_Src_SrcB_LCK_Y	P06239	LCK	P06239	LCK	Y505	Q508H	508	Missense	distal	3	no	6.755	7.863	PhosphoSitePlus;EPSD	COSMIC	5.050	Up-regulation
TK_Src_SrcB_LCK_Y	Q8IWV1	LAX1	P06239	LCK	Y93	Q100L	100	Missense	distal	7	no	5.216	5.012	EPSD	COSMIC	5.050	Loss
TK_Src_SrcB_LCK_Y	Q8IWV1	LAX1	P06239	LCK	Y93	A89V	89	Missense	distal	-4	no	5.216	5.101	EPSD	COSMIC	5.050	Down-regulation
TK_Src_SrcB_LCK_Y	Q8IWV1	LAX1	P06239	LCK	Y93	Q100K	100	Missense	distal	7	no	5.216	5.057	EPSD	COSMIC	5.050	Down-regulation
TK_Src_SrcB_LCK_Y	Q8IWV1	LAX1	P06239	LCK	Y93	I95T	95	Missense	proximal	2	no	5.216	6.368	EPSD	COSMIC	5.050	Up-regulation
TK_Src_SrcB_LCK_Y	Q8IWV1	LAX1	P06239	LCK	Y93	R99Q	99	Missense	distal	6	no	5.216	5.618	EPSD	COSMIC;GDSC	5.050	Up-regulation
TK_Src_SrcB_LCK_Y	Q8IWV1	LAX1	P06239	LCK	Y93	W98L	98	Missense	distal	5	no	5.216	5.168	EPSD	COSMIC	5.050	Down-regulation
TK_Src_SrcB_LCK_Y	Q8IWV1	LAX1	P06239	LCK	Y373	E368K	368	Missense	distal	-5	no	7.808	7.148	EPSD;PhosphoSitePlus	COSMIC	5.050	Down-regulation
TK_Src_SrcB_LCK_Y	Q8IWV1	LAX1	P06239	LCK	Y373	D372N	372	Missense	proximal	-1	no	7.808	5.295	EPSD;PhosphoSitePlus	COSMIC;GDSC;CCLE	5.050	Down-regulation
TK_Src_SrcB_LCK_Y	Q8IWV1	LAX1	P06239	LCK	Y373	S370F	370	Missense	distal	-3	no	7.808	7.555	EPSD;PhosphoSitePlus	COSMIC	5.050	Down-regulation
TK_Src_SrcB_LCK_Y	P15498	VAV1	P06239	LCK	Y142	D138N	138	Missense	distal	-4	no	7.950	7.304	EPSD;PhosphoSitePlus	COSMIC	5.050	Down-regulation
TK_Src_SrcB_LCK_Y	P15498	VAV1	P06239	LCK	Y160	E157K	157	Missense	distal	-3	no	10.123	8.840	PhosphoSitePlus;EPSD	COSMIC	5.050	Down-regulation
TK_Src_SrcB_LCK_Y	P15498	VAV1	P06239	LCK	Y174	E175V	175	Missense	proximal	1	no	10.500	9.396	EPSD;PhosphoSitePlus	COSMIC	5.050	Down-regulation
TK_Src_SrcB_LCK_Y	P15498	VAV1	P06239	LCK	Y174	Y174C	174	Missense	central	0	yes	10.500	0.000	EPSD;PhosphoSitePlus	COSMIC	5.050	Loss
TK_Src_SrcB_LCK_Y	P15498	VAV1	P06239	LCK	Y174	E175L	175	Missense	proximal	1	no	10.500	9.529	EPSD;PhosphoSitePlus	COSMIC	5.050	Down-regulation
TK_Src_SrcB_LCK_Y	P15498	VAV1	P06239	LCK	Y174	M178R	178	Missense	distal	4	no	10.500	10.884	EPSD;PhosphoSitePlus	COSMIC	5.050	Up-regulation
TK_Src_SrcB_LCK_Y	P15498	VAV1	P06239	LCK	Y174	L177R	177	Missense	distal	3	no	10.500	9.452	EPSD;PhosphoSitePlus	COSMIC	5.050	Down-regulation
TK_Src_SrcB_LCK_Y	P15498	VAV1	P06239	LCK	Y174	D176N	176	Missense	proximal	2	no	10.500	10.754	EPSD;PhosphoSitePlus	COSMIC	5.050	Up-regulation
TK_Src_SrcB_LCK_Y	P15498	VAV1	P06239	LCK	Y267	A264T	264	Missense	distal	-3	no	4.862	5.636	EPSD	COSMIC	5.050	Gain
TK_Src_SrcB_LCK_Y	P15498	VAV1	P06239	LCK	Y267	G262E	262	Missense	distal	-5	no	4.862	5.387	EPSD	COSMIC	5.050	Gain
TK_Src_SrcB_LCK_Y	P15498	VAV1	P06239	LCK	Y603	E602K	602	Missense	proximal	-1	no	5.374	2.519	EPSD	COSMIC	5.050	Loss
TK_Src_SrcB_LCK_Y	P29350	PTPN6	P06239	LCK	Y509	A513T	513	Missense	distal	4	no	5.697	5.314	EPSD	COSMIC;GDSC;CCLE	5.050	Down-regulation
TK_Src_SrcB_LCK_Y	P29350	PTPN6	P06239	LCK	Y509	Q514K	514	Missense	distal	5	no	5.697	5.726	EPSD	COSMIC;CCLE	5.050	Up-regulation
TK_Src_SrcB_LCK_Y	P29350	PTPN6	P06239	LCK	Y536	E535G	535	Missense	proximal	-1	no	6.084	4.230	EPSD;PhosphoSitePlus	COSMIC	5.050	Loss
TK_Src_SrcB_LCK_Y	P29350	PTPN6	P06239	LCK	Y536	G537R	537	Missense	proximal	1	no	6.084	6.256	EPSD;PhosphoSitePlus	COSMIC	5.050	Up-regulation
TK_Src_SrcB_LCK_Y	P29350	PTPN6	P06239	LCK	Y564	N571Y	571	Missense	distal	7	no	10.692	10.682	PhosphoSitePlus;EPSD	COSMIC	5.050	Down-regulation
TK_Src_SrcB_LCK_Y	Q13094	LCP2	P06239	LCK	Y113	D112N	112	Missense	proximal	-1	no	8.611	6.098	EPSD;PhosphoSitePlus	COSMIC;GDSC;CCLE	5.050	Down-regulation
TK_Src_SrcB_LCK_Y	Q13094	LCP2	P06239	LCK	Y113	D119Y	119	Missense	distal	6	no	8.611	8.909	EPSD;PhosphoSitePlus	COSMIC	5.050	Up-regulation
TK_Src_SrcB_LCK_Y	Q13094	LCP2	P06239	LCK	Y113	E109K	109	Missense	distal	-4	no	8.611	7.808	EPSD;PhosphoSitePlus	COSMIC	5.050	Down-regulation
TK_Src_SrcB_LCK_Y	Q13094	LCP2	P06239	LCK	Y113	S115I	115	Missense	proximal	2	no	8.611	7.079	EPSD;PhosphoSitePlus	COSMIC	5.050	Down-regulation
TK_Src_SrcB_LCK_Y	Q13094	LCP2	P06239	LCK	Y145	P138R	138	Missense	distal	-7	no	8.816	8.943	PhosphoSitePlus;EPSD	COSMIC;GDSC;CCLE	5.050	Up-regulation
TK_Src_SrcB_LCK_Y	Q13094	LCP2	P06239	LCK	Y145	A143T	143	Missense	proximal	-2	no	8.816	8.792	PhosphoSitePlus;EPSD	COSMIC;GDSC;CCLE	5.050	Down-regulation
TK_Src_SrcB_LCK_Y	Q13094	LCP2	P06239	LCK	Y145	A143V	143	Missense	proximal	-2	no	8.816	8.381	PhosphoSitePlus;EPSD	COSMIC	5.050	Down-regulation
TK_Src_SrcB_LCK_Y	Q13094	LCP2	P06239	LCK	Y145	P149T	149	Missense	distal	4	no	8.816	8.572	PhosphoSitePlus;EPSD	COSMIC	5.050	Down-regulation
TK_Src_SrcB_LCK_Y	Q13094	LCP2	P06239	LCK	Y145	P149L	149	Missense	distal	4	no	8.816	8.401	PhosphoSitePlus;EPSD	COSMIC	5.050	Down-regulation
TK_Src_SrcB_LCK_Y	Q8N1K5	THEMIS	P06239	LCK	Y540	E538D	538	Missense	proximal	-2	no	8.032	8.281	EPSD;PhosphoSitePlus	COSMIC	5.050	Up-regulation
TK_Src_SrcB_LCK_Y	Q8N1K5	THEMIS	P06239	LCK	Y540	E537K	537	Missense	distal	-3	no	8.032	6.748	EPSD;PhosphoSitePlus	COSMIC	5.050	Down-regulation
TK_Src_SrcB_LCK_Y	Q8N1K5	THEMIS	P06239	LCK	Y541	E538D	538	Missense	distal	-3	no	6.248	6.819	PhosphoSitePlus;EPSD	COSMIC	5.050	Up-regulation
TK_Src_SrcB_LCK_Y	Q8N1K5	THEMIS	P06239	LCK	Y541	E537K	537	Missense	distal	-4	no	6.248	5.444	PhosphoSitePlus;EPSD	COSMIC	5.050	Down-regulation
TK_Src_SrcB_LCK_Y	Q16539	MAPK14	P06239	LCK	Y182	T185I	185	Missense	distal	3	no	7.120	7.832	EPSD	COSMIC	5.050	Up-regulation
TK_Src_SrcB_LCK_Y	Q16539	MAPK14	P06239	LCK	Y323	P322R	322	Missense	proximal	-1	no	6.587	6.130	PhosphoSitePlus	COSMIC;CCLE	5.050	Down-regulation
TK_Src_SrcB_LCK_Y	Q16539	MAPK14	P06239	LCK	Y323	V319L	319	Missense	distal	-4	no	6.587	6.016	PhosphoSitePlus	COSMIC	5.050	Down-regulation
TK_Src_SrcB_LCK_Y	P42229	STAT5A	P06239	LCK	Y171	Q177K	177	Missense	distal	6	no	6.645	6.848	EPSD	COSMIC	5.050	Up-regulation
TK_Src_SrcB_LCK_Y	P42229	STAT5A	P06239	LCK	Y171	Y171S	171	Missense	central	0	yes	6.645	0.000	EPSD	COSMIC	5.050	Loss
TK_Src_SrcB_LCK_Y	P42229	STAT5A	P06239	LCK	Y668	F670L	670	Missense	proximal	2	no	5.431	5.176	EPSD	COSMIC	5.050	Down-regulation
TK_Src_SrcB_LCK_Y	P42229	STAT5A	P06239	LCK	Y694	A688D	688	Missense	distal	-6	no	5.862	5.764	PhosphoSitePlus	COSMIC	5.050	Down-regulation
TK_Src_SrcB_LCK_Y	Q13291	SLAMF1	P06239	LCK	Y281	A282T	282	Missense	proximal	1	no	5.141	5.669	EPSD	COSMIC	5.050	Up-regulation
TK_Src_SrcB_LCK_Y	Q13291	SLAMF1	P06239	LCK	Y281	T279K	279	Missense	proximal	-2	no	5.141	5.400	EPSD	COSMIC	5.050	Up-regulation
TK_Src_SrcB_LCK_Y	Q13291	SLAMF1	P06239	LCK	Y307	C303Y	303	Missense	distal	-4	no	7.153	8.508	PhosphoSitePlus	COSMIC	5.050	Up-regulation
TK_Src_SrcB_LCK_Y	Q13291	SLAMF1	P06239	LCK	Y307	Y307C	307	Missense	central	0	yes	7.153	0.000	PhosphoSitePlus	COSMIC	5.050	Loss
TK_Src_SrcB_LCK_Y	Q13291	SLAMF1	P06239	LCK	Y327	T321K	321	Missense	distal	-6	no	7.182	6.959	EPSD	COSMIC	5.050	Down-regulation
TK_Src_SrcB_LCK_Y	Q13291	SLAMF1	P06239	LCK	Y327	S323F	323	Missense	distal	-4	no	7.182	6.635	EPSD	COSMIC	5.050	Down-regulation
TK_Src_SrcB_LCK_Y	Q13444	ADAM15	P06239	LCK	Y715	S714I	714	Missense	proximal	-1	no	3.353	5.667	PhosphoSitePlus	COSMIC	5.050	Gain
TK_Src_SrcB_LCK_Y	Q13444	ADAM15	P06239	LCK	Y735	T732N	732	Missense	distal	-3	no	6.300	6.671	EPSD	COSMIC	5.050	Up-regulation
TK_Src_SrcB_LCK_Y	Q13444	ADAM15	P06239	LCK	Y735	T732P	732	Missense	distal	-3	no	6.300	5.423	EPSD	COSMIC;GDSC	5.050	Down-regulation
TK_Src_SrcB_LCK_Y	Q13444	ADAM15	P06239	LCK	Y735	G741C	741	Missense	distal	6	no	6.300	7.047	EPSD	COSMIC	5.050	Up-regulation
TK_Src_SrcB_LCK_Y	P22681	CBL	P06239	LCK	Y141	R139T	139	Missense	proximal	-2	no	6.165	6.006	EPSD	COSMIC	5.050	Down-regulation
TK_Src_SrcB_LCK_Y	P22681	CBL	P06239	LCK	Y141	Y141C	141	Missense	central	0	yes	6.165	0.000	EPSD	COSMIC	5.050	Loss
TK_Src_SrcB_LCK_Y	P22681	CBL	P06239	LCK	Y371	M374V	374	Missense	distal	3	no	5.315	5.100	EPSD	COSMIC	5.050	Down-regulation
TK_Src_SrcB_LCK_Y	P22681	CBL	P06239	LCK	Y371	Y371S	371	Missense	central	0	yes	5.315	0.000	EPSD	COSMIC	5.050	Loss
TK_Src_SrcB_LCK_Y	P22681	CBL	P06239	LCK	Y371	Y371N	371	Missense	central	0	yes	5.315	0.000	EPSD	COSMIC	5.050	Loss
TK_Src_SrcB_LCK_Y	P22681	CBL	P06239	LCK	Y371	Q367P	367	Missense	distal	-4	no	5.315	5.450	EPSD	COSMIC	5.050	Up-regulation
TK_Src_SrcB_LCK_Y	P22681	CBL	P06239	LCK	Y371	Y368N	368	Missense	distal	-3	no	5.315	5.499	EPSD	COSMIC	5.050	Up-regulation
TK_Src_SrcB_LCK_Y	P22681	CBL	P06239	LCK	Y371	Y371C	371	Missense	central	0	yes	5.315	0.000	EPSD	COSMIC	5.050	Loss
TK_Src_SrcB_LCK_Y	P22681	CBL	P06239	LCK	Y371	Y371D	371	Missense	central	0	yes	5.315	0.000	EPSD	COSMIC	5.050	Loss
TK_Src_SrcB_LCK_Y	P22681	CBL	P06239	LCK	Y371	Q367R	367	Missense	distal	-4	no	5.315	4.968	EPSD	COSMIC	5.050	Loss
TK_Src_SrcB_LCK_Y	P22681	CBL	P06239	LCK	Y371	S376F	376	Missense	distal	5	no	5.315	5.466	EPSD	COSMIC	5.050	Up-regulation
TK_Src_SrcB_LCK_Y	P22681	CBL	P06239	LCK	Y371	L370F	370	Missense	proximal	-1	no	5.315	4.509	EPSD	COSMIC	5.050	Loss
TK_Src_SrcB_LCK_Y	P22681	CBL	P06239	LCK	Y371	T377A	377	Missense	distal	6	no	5.315	5.203	EPSD	COSMIC	5.050	Down-regulation
TK_Src_SrcB_LCK_Y	P22681	CBL	P06239	LCK	Y371	E366D	366	Missense	distal	-5	no	5.315	4.922	EPSD	COSMIC	5.050	Loss
TK_Src_SrcB_LCK_Y	P22681	CBL	P06239	LCK	Y371	E366Q	366	Missense	distal	-5	no	5.315	4.690	EPSD	COSMIC	5.050	Loss
TK_Src_SrcB_LCK_Y	P22681	CBL	P06239	LCK	Y371	G375P	375	Missense	distal	4	no	5.315	5.555	EPSD	COSMIC	5.050	Up-regulation
TK_Src_SrcB_LCK_Y	P22681	CBL	P06239	LCK	Y371	G375S	375	Missense	distal	4	no	5.315	5.669	EPSD	COSMIC	5.050	Up-regulation
TK_Src_SrcB_LCK_Y	P22681	CBL	P06239	LCK	Y455	E448Q	448	Missense	distal	-7	no	5.839	5.515	EPSD	COSMIC	5.050	Down-regulation
TK_Src_SrcB_LCK_Y	P22681	CBL	P06239	LCK	Y455	D456N	456	Missense	proximal	1	no	5.839	5.248	EPSD	COSMIC	5.050	Down-regulation
TK_Src_SrcB_LCK_Y	P22681	CBL	P06239	LCK	Y455	N454D	454	Missense	proximal	-1	no	5.839	8.352	EPSD	COSMIC	5.050	Up-regulation
TK_Src_SrcB_LCK_Y	P22681	CBL	P06239	LCK	Y455	D458N	458	Missense	distal	3	no	5.839	5.576	EPSD	COSMIC	5.050	Down-regulation
TK_Src_SrcB_LCK_Y	P22681	CBL	P06239	LCK	Y455	G449V	449	Missense	distal	-6	no	5.839	5.610	EPSD	COSMIC	5.050	Down-regulation
TK_Src_SrcB_LCK_Y	P22681	CBL	P06239	LCK	Y674	S675C	675	Missense	proximal	1	no	8.284	7.359	EPSD	COSMIC	5.050	Down-regulation
TK_Src_SrcB_LCK_Y	P22681	CBL	P06239	LCK	Y674	A677V	677	Missense	distal	3	no	8.284	8.138	EPSD	COSMIC	5.050	Down-regulation
TK_Src_SrcB_LCK_Y	P22681	CBL	P06239	LCK	Y674	A678V	678	Missense	distal	4	no	8.284	7.405	EPSD	COSMIC	5.050	Down-regulation
TK_Src_SrcB_LCK_Y	P22681	CBL	P06239	LCK	Y674	A678T	678	Missense	distal	4	no	8.284	7.902	EPSD	COSMIC	5.050	Down-regulation
TK_Src_SrcB_LCK_Y	P22681	CBL	P06239	LCK	Y700	G694D	694	Missense	distal	-6	no	8.996	9.488	PhosphoSitePlus;EPSD	COSMIC	5.050	Up-regulation
TK_Src_SrcB_LCK_Y	P22681	CBL	P06239	LCK	Y700	M701V	701	Missense	proximal	1	no	8.996	8.554	PhosphoSitePlus;EPSD	COSMIC	5.050	Down-regulation
TK_Src_SrcB_LCK_Y	P22681	CBL	P06239	LCK	Y700	P703L	703	Missense	distal	3	no	8.996	9.711	PhosphoSitePlus;EPSD	COSMIC	5.050	Up-regulation
TK_Src_SrcB_LCK_Y	P22681	CBL	P06239	LCK	Y700	S704C	704	Missense	distal	4	no	8.996	7.860	PhosphoSitePlus;EPSD	COSMIC	5.050	Down-regulation
TK_Src_SrcB_LCK_Y	P22681	CBL	P06239	LCK	Y700	P707L	707	Missense	distal	7	no	8.996	8.895	PhosphoSitePlus;EPSD	COSMIC	5.050	Down-regulation
TK_Src_SrcB_LCK_Y	P22681	CBL	P06239	LCK	Y700	S705C	705	Missense	distal	5	no	8.996	9.292	PhosphoSitePlus;EPSD	COSMIC	5.050	Up-regulation
TK_Src_SrcB_LCK_Y	P22681	CBL	P06239	LCK	Y700	R706T	706	Missense	distal	6	no	8.996	9.205	PhosphoSitePlus;EPSD	COSMIC	5.050	Up-regulation
TK_Src_SrcB_LCK_Y	P22681	CBL	P06239	LCK	Y731	S728N	728	Missense	distal	-3	no	8.083	9.036	EPSD;PhosphoSitePlus	COSMIC	5.050	Up-regulation
TK_Src_SrcB_LCK_Y	P22681	CBL	P06239	LCK	Y731	Y731C	731	Missense	central	0	yes	8.083	0.000	EPSD;PhosphoSitePlus	COSMIC	5.050	Loss
TK_Src_SrcB_LCK_Y	P60484	PTEN	P06239	LCK	Y68	C71S	71	Missense	distal	3	no	4.757	5.712	EPSD	COSMIC	5.050	Gain
TK_Src_SrcB_LCK_Y	P60484	PTEN	P06239	LCK	Y68	C71W	71	Missense	distal	3	no	4.757	5.498	EPSD	COSMIC	5.050	Gain
TK_Src_SrcB_LCK_Y	P60484	PTEN	P06239	LCK	Y68	C71F	71	Missense	distal	3	no	4.757	5.809	EPSD	COSMIC	5.050	Gain
TK_Src_SrcB_LCK_Y	P60484	PTEN	P06239	LCK	Y68	K66E	66	Missense	proximal	-2	no	4.757	5.328	EPSD	COSMIC	5.050	Gain
TK_Src_SrcB_LCK_Y	P60484	PTEN	P06239	LCK	Y155	Y155H	155	Missense	central	0	yes	5.347	0.000	EPSD	COSMIC	5.050	Loss
TK_Src_SrcB_LCK_Y	P60484	PTEN	P06239	LCK	Y155	R161G	161	Missense	distal	6	no	5.347	5.839	EPSD	COSMIC	5.050	Up-regulation
TK_Src_SrcB_LCK_Y	P60484	PTEN	P06239	LCK	Y155	A151D	151	Missense	distal	-4	no	5.347	6.058	EPSD	COSMIC	5.050	Up-regulation
TK_Src_SrcB_LCK_Y	P60484	PTEN	P06239	LCK	Y155	G156W	156	Missense	proximal	1	no	5.347	4.671	EPSD	COSMIC	5.050	Loss
TK_Src_SrcB_LCK_Y	P60484	PTEN	P06239	LCK	Y155	Y155N	155	Missense	central	0	yes	5.347	0.000	EPSD	COSMIC	5.050	Loss
TK_Src_SrcB_LCK_Y	P60484	PTEN	P06239	LCK	Y155	A148T	148	Missense	distal	-7	no	5.347	5.007	EPSD	COSMIC	5.050	Loss
TK_Src_SrcB_LCK_Y	P60484	PTEN	P06239	LCK	Y155	L152V	152	Missense	distal	-3	no	5.347	5.951	EPSD	COSMIC	5.050	Up-regulation
TK_Src_SrcB_LCK_Y	P60484	PTEN	P06239	LCK	Y155	A151T	151	Missense	distal	-4	no	5.347	5.563	EPSD	COSMIC	5.050	Up-regulation
TK_Src_SrcB_LCK_Y	P60484	PTEN	P06239	LCK	Y155	R161K	161	Missense	distal	6	no	5.347	5.951	EPSD	COSMIC	5.050	Up-regulation
TK_Src_SrcB_LCK_Y	P60484	PTEN	P06239	LCK	Y155	D162H	162	Missense	distal	7	no	5.347	5.315	EPSD	COSMIC;GDSC;CCLE	5.050	Down-regulation
TK_Src_SrcB_LCK_Y	P60484	PTEN	P06239	LCK	Y155	A148E	148	Missense	distal	-7	no	5.347	5.441	EPSD	COSMIC	5.050	Up-regulation
TK_Src_SrcB_LCK_Y	P60484	PTEN	P06239	LCK	Y155	Y155S	155	Missense	central	0	yes	5.347	0.000	EPSD	COSMIC	5.050	Loss
TK_Src_SrcB_LCK_Y	P60484	PTEN	P06239	LCK	Y155	R159M	159	Missense	distal	4	no	5.347	4.964	EPSD	COSMIC	5.050	Loss
TK_Src_SrcB_LCK_Y	P60484	PTEN	P06239	LCK	Y155	G156R	156	Missense	proximal	1	no	5.347	5.520	EPSD	COSMIC	5.050	Up-regulation
TK_Src_SrcB_LCK_Y	P60484	PTEN	P06239	LCK	Y155	T160I	160	Missense	distal	5	no	5.347	5.515	EPSD	COSMIC	5.050	Up-regulation
TK_Src_SrcB_LCK_Y	P60484	PTEN	P06239	LCK	Y155	Q149K	149	Missense	distal	-6	no	5.347	5.005	EPSD	COSMIC	5.050	Loss
TK_Src_SrcB_LCK_Y	P60484	PTEN	P06239	LCK	Y155	E150Q	150	Missense	distal	-5	no	5.347	4.722	EPSD	COSMIC	5.050	Loss
TK_Src_SrcB_LCK_Y	P60484	PTEN	P06239	LCK	Y155	F154S	154	Missense	proximal	-1	no	5.347	4.569	EPSD	COSMIC	5.050	Loss
TK_Src_SrcB_LCK_Y	P60484	PTEN	P06239	LCK	Y155	D162Y	162	Missense	distal	7	no	5.347	5.198	EPSD	COSMIC	5.050	Down-regulation
TK_Src_SrcB_LCK_Y	P60484	PTEN	P06239	LCK	Y155	L152Q	152	Missense	distal	-3	no	5.347	6.465	EPSD	COSMIC	5.050	Up-regulation
TK_Src_SrcB_LCK_Y	P60484	PTEN	P06239	LCK	Y155	E157K	157	Missense	proximal	2	no	5.347	5.321	EPSD	COSMIC	5.050	Down-regulation
TK_Src_SrcB_LCK_Y	P60484	PTEN	P06239	LCK	Y155	E150D	150	Missense	distal	-5	no	5.347	4.954	EPSD	COSMIC	5.050	Loss
TK_Src_SrcB_LCK_Y	P60484	PTEN	P06239	LCK	Y155	A151G	151	Missense	distal	-4	no	5.347	5.154	EPSD	COSMIC	5.050	Down-regulation
TK_Src_SrcB_LCK_Y	P60484	PTEN	P06239	LCK	Y155	F154V	154	Missense	proximal	-1	no	5.347	6.497	EPSD	COSMIC	5.050	Up-regulation
TK_Src_SrcB_LCK_Y	P60484	PTEN	P06239	LCK	Y155	Q149R	149	Missense	distal	-6	no	5.347	5.174	EPSD	COSMIC	5.050	Down-regulation
TK_Src_SrcB_LCK_Y	P60484	PTEN	P06239	LCK	Y155	D153N	153	Missense	proximal	-2	no	5.347	4.753	EPSD	COSMIC	5.050	Loss
TK_Src_SrcB_LCK_Y	P60484	PTEN	P06239	LCK	Y155	T160S	160	Missense	distal	5	no	5.347	5.278	EPSD	COSMIC	5.050	Down-regulation
TK_Src_SrcB_LCK_Y	P60484	PTEN	P06239	LCK	Y155	L152I	152	Missense	distal	-3	no	5.347	5.739	EPSD	COSMIC	5.050	Up-regulation
TK_Src_SrcB_LCK_Y	P60484	PTEN	P06239	LCK	Y155	D162G	162	Missense	distal	7	no	5.347	5.249	EPSD	COSMIC	5.050	Down-regulation
TK_Src_SrcB_LCK_Y	P60484	PTEN	P06239	LCK	Y155	T160A	160	Missense	distal	5	no	5.347	5.323	EPSD	COSMIC	5.050	Down-regulation
TK_Src_SrcB_LCK_Y	P60484	PTEN	P06239	LCK	Y155	R161I	161	Missense	distal	6	no	5.347	5.715	EPSD	COSMIC	5.050	Up-regulation
TK_Src_SrcB_LCK_Y	P60484	PTEN	P06239	LCK	Y155	E150G	150	Missense	distal	-5	no	5.347	4.822	EPSD	COSMIC	5.050	Loss
TK_Src_SrcB_LCK_Y	P60484	PTEN	P06239	LCK	Y176	L181Q	181	Missense	distal	5	no	5.532	5.364	EPSD	COSMIC	5.050	Down-regulation
TK_Src_SrcB_LCK_Y	P60484	PTEN	P06239	LCK	Y176	Y176F	176	Missense	central	0	yes	5.532	0.000	EPSD	COSMIC	5.050	Loss
TK_Src_SrcB_LCK_Y	P60484	PTEN	P06239	LCK	Y176	Y174D	174	Missense	proximal	-2	no	5.532	6.618	EPSD	COSMIC	5.050	Up-regulation
TK_Src_SrcB_LCK_Y	P60484	PTEN	P06239	LCK	Y176	Y174N	174	Missense	proximal	-2	no	5.532	6.024	EPSD	COSMIC	5.050	Up-regulation
TK_Src_SrcB_LCK_Y	P60484	PTEN	P06239	LCK	Y176	R172W	172	Missense	distal	-4	no	5.532	4.769	EPSD	COSMIC	5.050	Loss
TK_Src_SrcB_LCK_Y	P60484	PTEN	P06239	LCK	Y176	R173P	173	Missense	distal	-3	no	5.532	4.668	EPSD	COSMIC;GDSC;CCLE	5.050	Loss
TK_Src_SrcB_LCK_Y	P60484	PTEN	P06239	LCK	Y176	L182F	182	Missense	distal	6	no	5.532	5.534	EPSD	COSMIC	5.050	Up-regulation
TK_Src_SrcB_LCK_Y	P60484	PTEN	P06239	LCK	Y176	P169S	169	Missense	distal	-7	no	5.532	5.631	EPSD	COSMIC	5.050	Up-regulation
TK_Src_SrcB_LCK_Y	P60484	PTEN	P06239	LCK	Y176	V175M	175	Missense	proximal	-1	no	5.532	5.036	EPSD	COSMIC	5.050	Loss
TK_Src_SrcB_LCK_Y	P60484	PTEN	P06239	LCK	Y176	Y178H	178	Missense	proximal	2	no	5.532	6.153	EPSD	COSMIC	5.050	Up-regulation
TK_Src_SrcB_LCK_Y	P60484	PTEN	P06239	LCK	Y176	L182V	182	Missense	distal	6	no	5.532	5.534	EPSD	COSMIC	5.050	Up-regulation
TK_Src_SrcB_LCK_Y	P60484	PTEN	P06239	LCK	Y176	Y177H	177	Missense	proximal	1	no	5.532	4.806	EPSD	COSMIC	5.050	Loss
TK_Src_SrcB_LCK_Y	P60484	PTEN	P06239	LCK	Y176	Q171P	171	Missense	distal	-5	no	5.532	5.912	EPSD	COSMIC	5.050	Up-regulation
TK_Src_SrcB_LCK_Y	P60484	PTEN	P06239	LCK	Y176	P169H	169	Missense	distal	-7	no	5.532	5.557	EPSD	COSMIC	5.050	Up-regulation
TK_Src_SrcB_LCK_Y	P60484	PTEN	P06239	LCK	Y176	K183N	183	Missense	distal	7	no	5.532	5.508	EPSD	COSMIC	5.050	Down-regulation
TK_Src_SrcB_LCK_Y	P60484	PTEN	P06239	LCK	Y176	P169L	169	Missense	distal	-7	no	5.532	5.600	EPSD	COSMIC	5.050	Up-regulation
TK_Src_SrcB_LCK_Y	P60484	PTEN	P06239	LCK	Y176	S179I	179	Missense	distal	3	no	5.532	5.762	EPSD	COSMIC	5.050	Up-regulation
TK_Src_SrcB_LCK_Y	P60484	PTEN	P06239	LCK	Y176	Y176C	176	Missense	central	0	yes	5.532	0.000	EPSD	COSMIC	5.050	Loss
TK_Src_SrcB_LCK_Y	P60484	PTEN	P06239	LCK	Y176	Y178D	178	Missense	proximal	2	no	5.532	5.871	EPSD	COSMIC	5.050	Up-regulation
TK_Src_SrcB_LCK_Y	P60484	PTEN	P06239	LCK	Y176	V175A	175	Missense	proximal	-1	no	5.532	3.960	EPSD	COSMIC	5.050	Loss
TK_Src_SrcB_LCK_Y	P60484	PTEN	P06239	LCK	Y176	Y174C	174	Missense	proximal	-2	no	5.532	4.281	EPSD	COSMIC	5.050	Loss
TK_Src_SrcB_LCK_Y	P60484	PTEN	P06239	LCK	Y176	Y178F	178	Missense	proximal	2	no	5.532	5.620	EPSD	COSMIC	5.050	Up-regulation
TK_Src_SrcB_LCK_Y	P60484	PTEN	P06239	LCK	Y176	Q171H	171	Missense	distal	-5	no	5.532	5.776	EPSD	COSMIC	5.050	Up-regulation
TK_Src_SrcB_LCK_Y	P60484	PTEN	P06239	LCK	Y176	R173S	173	Missense	distal	-3	no	5.532	4.963	EPSD	COSMIC	5.050	Loss
TK_Src_SrcB_LCK_Y	P60484	PTEN	P06239	LCK	Y176	L181R	181	Missense	distal	5	no	5.532	5.366	EPSD	COSMIC	5.050	Down-regulation
TK_Src_SrcB_LCK_Y	P60484	PTEN	P06239	LCK	Y176	Y178N	178	Missense	proximal	2	no	5.532	6.125	EPSD	COSMIC	5.050	Up-regulation
TK_Src_SrcB_LCK_Y	P60484	PTEN	P06239	LCK	Y176	Y174H	174	Missense	proximal	-2	no	5.532	5.147	EPSD	COSMIC	5.050	Down-regulation
TK_Src_SrcB_LCK_Y	P60484	PTEN	P06239	LCK	Y240	R234Q	234	Missense	distal	-6	no	6.412	6.585	EPSD;PhosphoSitePlus	COSMIC	5.050	Up-regulation
TK_Src_SrcB_LCK_Y	P60484	PTEN	P06239	LCK	Y240	D236E	236	Missense	distal	-4	no	6.412	6.488	EPSD;PhosphoSitePlus	COSMIC	5.050	Up-regulation
TK_Src_SrcB_LCK_Y	P60484	PTEN	P06239	LCK	Y240	F241V	241	Missense	proximal	1	no	6.412	6.582	EPSD;PhosphoSitePlus	COSMIC	5.050	Up-regulation
TK_Src_SrcB_LCK_Y	P60484	PTEN	P06239	LCK	Y240	F238L	238	Missense	proximal	-2	no	6.412	5.897	EPSD;PhosphoSitePlus	COSMIC	5.050	Down-regulation
TK_Src_SrcB_LCK_Y	P60484	PTEN	P06239	LCK	Y240	E242K	242	Missense	proximal	2	no	6.412	6.385	EPSD;PhosphoSitePlus	COSMIC	5.050	Down-regulation
TK_Src_SrcB_LCK_Y	P60484	PTEN	P06239	LCK	Y240	R233G	233	Missense	distal	-7	no	6.412	6.108	EPSD;PhosphoSitePlus	COSMIC;CCLE	5.050	Down-regulation
TK_Src_SrcB_LCK_Y	P60484	PTEN	P06239	LCK	Y240	R234G	234	Missense	distal	-6	no	6.412	6.136	EPSD;PhosphoSitePlus	COSMIC;CCLE	5.050	Down-regulation
TK_Src_SrcB_LCK_Y	P60484	PTEN	P06239	LCK	Y240	F243L	243	Missense	distal	3	no	6.412	6.690	EPSD;PhosphoSitePlus	COSMIC	5.050	Up-regulation
TK_Src_SrcB_LCK_Y	P60484	PTEN	P06239	LCK	Y240	E235G	235	Missense	distal	-5	no	6.412	5.887	EPSD;PhosphoSitePlus	COSMIC	5.050	Down-regulation
TK_Src_SrcB_LCK_Y	P60484	PTEN	P06239	LCK	Y240	R234W	234	Missense	distal	-6	no	6.412	5.688	EPSD;PhosphoSitePlus	COSMIC	5.050	Down-regulation
TK_Src_SrcB_LCK_Y	P60484	PTEN	P06239	LCK	Y240	E235K	235	Missense	distal	-5	no	6.412	5.752	EPSD;PhosphoSitePlus	COSMIC	5.050	Down-regulation
TK_Src_SrcB_LCK_Y	P60484	PTEN	P06239	LCK	Y240	R234L	234	Missense	distal	-6	no	6.412	6.303	EPSD;PhosphoSitePlus	COSMIC	5.050	Down-regulation
TK_Src_SrcB_LCK_Y	P60484	PTEN	P06239	LCK	Y240	F241L	241	Missense	proximal	1	no	6.412	6.715	EPSD;PhosphoSitePlus	COSMIC;GDSC;CCLE	5.050	Up-regulation
TK_Src_SrcB_LCK_Y	P60484	PTEN	P06239	LCK	Y240	P244S	244	Missense	distal	4	no	6.412	6.526	EPSD;PhosphoSitePlus	COSMIC	5.050	Up-regulation
TK_Src_SrcB_LCK_Y	P60484	PTEN	P06239	LCK	Y240	L247S	247	Missense	distal	7	no	6.412	6.566	EPSD;PhosphoSitePlus	COSMIC	5.050	Up-regulation
TK_Src_SrcB_LCK_Y	P60484	PTEN	P06239	LCK	Y315	L318F	318	Missense	distal	3	no	6.389	6.111	PhosphoSitePlus;EPSD	COSMIC	5.050	Down-regulation
TK_Src_SrcB_LCK_Y	P60484	PTEN	P06239	LCK	Y315	L320V	320	Missense	distal	5	no	6.389	6.383	PhosphoSitePlus;EPSD	COSMIC	5.050	Down-regulation
TK_Src_SrcB_LCK_Y	P60484	PTEN	P06239	LCK	Y315	Y315H	315	Missense	central	0	yes	6.389	0.000	PhosphoSitePlus;EPSD	COSMIC	5.050	Loss
TK_Src_SrcB_LCK_Y	P60484	PTEN	P06239	LCK	Y315	L318P	318	Missense	distal	3	no	6.389	5.674	PhosphoSitePlus;EPSD	COSMIC	5.050	Down-regulation
TK_Src_SrcB_LCK_Y	P60484	PTEN	P06239	LCK	Y315	R308H	308	Missense	distal	-7	no	6.389	6.287	PhosphoSitePlus;EPSD	COSMIC	5.050	Down-regulation
TK_Src_SrcB_LCK_Y	P60484	PTEN	P06239	LCK	Y315	V317G	317	Missense	proximal	2	no	6.389	6.836	PhosphoSitePlus;EPSD	COSMIC	5.050	Up-regulation
TK_Src_SrcB_LCK_Y	P60484	PTEN	P06239	LCK	Y315	E314K	314	Missense	proximal	-1	no	6.389	3.533	PhosphoSitePlus;EPSD	COSMIC	5.050	Loss
TK_Src_SrcB_LCK_Y	P60484	PTEN	P06239	LCK	Y315	T321I	321	Missense	distal	6	no	6.389	6.548	PhosphoSitePlus;EPSD	COSMIC	5.050	Up-regulation
TK_Src_SrcB_LCK_Y	P60484	PTEN	P06239	LCK	Y377	D375N	375	Missense	proximal	-2	no	6.975	6.381	EPSD	COSMIC	5.050	Down-regulation
TK_Src_SrcB_LCK_Y	P60484	PTEN	P06239	LCK	Y377	T383I	383	Missense	distal	6	no	6.975	7.134	EPSD	COSMIC	5.050	Up-regulation
TK_Src_SrcB_LCK_Y	P60484	PTEN	P06239	LCK	Y377	D384N	384	Missense	distal	7	no	6.975	6.836	EPSD	COSMIC	5.050	Down-regulation
TK_Src_SrcB_LCK_Y	P60484	PTEN	P06239	LCK	Y377	T382S	382	Missense	distal	5	no	6.975	6.906	EPSD	COSMIC	5.050	Down-regulation
TK_Src_SrcB_LCK_Y	P60484	PTEN	P06239	LCK	Y377	D384G	384	Missense	distal	7	no	6.975	6.877	EPSD	COSMIC	5.050	Down-regulation
TK_Src_SrcB_LCK_Y	Q04759	PRKCQ	P06239	LCK	Y90	E84D	84	Missense	distal	-6	no	7.972	7.476	PhosphoSitePlus	COSMIC	5.050	Down-regulation
TK_Src_SrcB_LCK_Y	Q04759	PRKCQ	P06239	LCK	Y90	C96F	96	Missense	distal	6	no	7.972	7.158	PhosphoSitePlus	COSMIC	5.050	Down-regulation
TK_Src_SrcB_LCK_Y	Q04759	PRKCQ	P06239	LCK	Y90	E84K	84	Missense	distal	-6	no	7.972	7.091	PhosphoSitePlus	COSMIC	5.050	Down-regulation
TK_Src_SrcB_LCK_Y	P05107	ITGB2	P06239	LCK	Y735	E741Q	741	Missense	distal	6	no	5.684	6.507	PhosphoSitePlus	COSMIC	5.050	Up-regulation
TK_Src_SrcB_LCK_Y	P05107	ITGB2	P06239	LCK	Y735	E734K	734	Missense	proximal	-1	no	5.684	2.828	PhosphoSitePlus	COSMIC	5.050	Loss
TK_Src_SrcB_LCK_Y	P05107	ITGB2	P06239	LCK	Y735	Y735N	735	Missense	central	0	yes	5.684	0.000	PhosphoSitePlus	COSMIC	5.050	Loss
TK_Src_SrcB_LCK_Y	P23743	DGKA	P06239	LCK	Y335	P331L	331	Missense	distal	-4	no	6.125	5.278	PhosphoSitePlus	COSMIC	5.050	Down-regulation
TK_Src_SrcB_LCK_Y	P24666	ACP1	P06239	LCK	Y132	S137C	137	Missense	distal	5	no	6.956	7.252	PhosphoSitePlus;EPSD	COSMIC	5.050	Up-regulation
TK_Src_SrcB_LCK_Y	P24666	ACP1	P06239	LCK	Y133	S137C	137	Missense	distal	4	no	5.981	4.844	EPSD;PhosphoSitePlus	COSMIC	5.050	Loss
TK_Src_SrcB_LCK_Y	P03372	ESR1	P06239	LCK	Y537	Y537D	537	Missense	central	0	yes	5.669	0.000	PhosphoSitePlus	COSMIC	5.050	Loss
TK_Src_SrcB_LCK_Y	P03372	ESR1	P06239	LCK	Y537	V534E	534	Missense	distal	-3	no	5.669	6.952	PhosphoSitePlus	COSMIC	5.050	Up-regulation
TK_Src_SrcB_LCK_Y	P03372	ESR1	P06239	LCK	Y537	E542G	542	Missense	distal	5	no	5.669	5.800	PhosphoSitePlus	COSMIC	5.050	Up-regulation
TK_Src_SrcB_LCK_Y	P03372	ESR1	P06239	LCK	Y537	C530L	530	Missense	distal	-7	no	5.669	6.295	PhosphoSitePlus	COSMIC	5.050	Up-regulation
TK_Src_SrcB_LCK_Y	P03372	ESR1	P06239	LCK	Y537	L536H	536	Missense	proximal	-1	no	5.669	5.009	PhosphoSitePlus	COSMIC	5.050	Loss
TK_Src_SrcB_LCK_Y	P03372	ESR1	P06239	LCK	Y537	L536P	536	Missense	proximal	-1	no	5.669	4.460	PhosphoSitePlus	COSMIC	5.050	Loss
TK_Src_SrcB_LCK_Y	P03372	ESR1	P06239	LCK	Y537	L536R	536	Missense	proximal	-1	no	5.669	4.004	PhosphoSitePlus	COSMIC	5.050	Loss
TK_Src_SrcB_LCK_Y	P03372	ESR1	P06239	LCK	Y537	L540Q	540	Missense	distal	3	no	5.669	4.640	PhosphoSitePlus	COSMIC	5.050	Loss
TK_Src_SrcB_LCK_Y	P03372	ESR1	P06239	LCK	Y537	N532K	532	Missense	distal	-5	no	5.669	5.538	PhosphoSitePlus	COSMIC	5.050	Down-regulation
TK_Src_SrcB_LCK_Y	P03372	ESR1	P06239	LCK	Y537	P535T	535	Missense	proximal	-2	no	5.669	5.535	PhosphoSitePlus	COSMIC	5.050	Down-regulation
TK_Src_SrcB_LCK_Y	P03372	ESR1	P06239	LCK	Y537	L536Q	536	Missense	proximal	-1	no	5.669	4.810	PhosphoSitePlus	COSMIC	5.050	Loss
TK_Src_SrcB_LCK_Y	P03372	ESR1	P06239	LCK	Y537	V534M	534	Missense	distal	-3	no	5.669	5.294	PhosphoSitePlus	COSMIC	5.050	Down-regulation
TK_Src_SrcB_LCK_Y	P03372	ESR1	P06239	LCK	Y537	K531E	531	Missense	distal	-6	no	5.669	6.550	PhosphoSitePlus	COSMIC	5.050	Up-regulation
TK_Src_SrcB_LCK_Y	P03372	ESR1	P06239	LCK	Y537	P535H	535	Missense	proximal	-2	no	5.669	5.143	PhosphoSitePlus	COSMIC	5.050	Down-regulation
TK_Src_SrcB_LCK_Y	Q96LC7	SIGLEC10	P06239	LCK	Y597	T593M	593	Missense	distal	-4	no	6.695	6.592	EPSD;PhosphoSitePlus	COSMIC	5.050	Down-regulation
TK_Src_SrcB_LCK_Y	Q96LC7	SIGLEC10	P06239	LCK	Y597	R590Q	590	Missense	distal	-7	no	6.695	6.555	EPSD;PhosphoSitePlus	COSMIC	5.050	Down-regulation
TK_Src_SrcB_LCK_Y	Q96LC7	SIGLEC10	P06239	LCK	Y597	I598N	598	Missense	proximal	1	no	6.695	7.484	EPSD;PhosphoSitePlus	COSMIC	5.050	Up-regulation
TK_Src_SrcB_LCK_Y	Q96LC7	SIGLEC10	P06239	LCK	Y597	N599K	599	Missense	proximal	2	no	6.695	6.867	EPSD;PhosphoSitePlus	COSMIC	5.050	Up-regulation
TK_Src_SrcB_LCK_Y	Q96LC7	SIGLEC10	P06239	LCK	Y597	Y597C	597	Missense	central	0	yes	6.695	0.000	EPSD;PhosphoSitePlus	COSMIC	5.050	Loss
TK_Src_SrcB_LCK_Y	Q96LC7	SIGLEC10	P06239	LCK	Y667	S661I	661	Missense	distal	-6	no	7.899	6.918	PhosphoSitePlus;EPSD	COSMIC	5.050	Down-regulation
TK_Src_SrcB_LCK_Y	P25963	NFKBIA	P06239	LCK	Y42	M37K	37	Missense	distal	-5	no	8.519	7.897	PhosphoSitePlus	COSMIC	5.050	Down-regulation
TK_Src_SrcB_LCK_Y	P25963	NFKBIA	P06239	LCK	Y42	E40D	40	Missense	proximal	-2	no	8.519	8.769	PhosphoSitePlus	COSMIC	5.050	Up-regulation
TK_Src_SrcB_LCK_Y	P25963	NFKBIA	P06239	LCK	Y42	M45L	45	Missense	distal	3	no	8.519	8.502	PhosphoSitePlus	COSMIC	5.050	Down-regulation
TK_Src_SrcB_LCK_Y	P25963	NFKBIA	P06239	LCK	Y42	E43K	43	Missense	proximal	1	no	8.519	7.571	PhosphoSitePlus	COSMIC	5.050	Down-regulation
TK_Src_SrcB_LCK_Y	P25963	NFKBIA	P06239	LCK	Y42	S36P	36	Missense	distal	-6	no	8.519	8.302	PhosphoSitePlus	COSMIC	5.050	Down-regulation
TK_Src_SrcB_LCK_Y	P25963	NFKBIA	P06239	LCK	Y42	E43Q	43	Missense	proximal	1	no	8.519	7.556	PhosphoSitePlus	COSMIC	5.050	Down-regulation
TK_Src_SrcB_LCK_Y	Q08881	ITK	P06239	LCK	Y180	E173A	173	Missense	distal	-7	no	6.469	6.375	EPSD	COSMIC	5.050	Down-regulation
TK_Src_SrcB_LCK_Y	Q08881	ITK	P06239	LCK	Y180	P187S	187	Missense	distal	7	no	6.469	6.521	EPSD	COSMIC	5.050	Up-regulation
TK_Src_SrcB_LCK_Y	Q08881	ITK	P06239	LCK	Y512	R505T	505	Missense	distal	-7	no	7.871	7.622	PhosphoSitePlus	COSMIC	5.050	Down-regulation
TK_Src_SrcB_LCK_Y	Q08881	ITK	P06239	LCK	Y512	D509Y	509	Missense	distal	-3	no	7.871	6.712	PhosphoSitePlus	COSMIC	5.050	Down-regulation
TK_Src_SrcB_LCK_Y	Q08881	ITK	P06239	LCK	Y512	V507I	507	Missense	distal	-5	no	7.871	7.476	PhosphoSitePlus	COSMIC	5.050	Down-regulation
TK_Src_SrcB_LCK_Y	P15311	EZR	P06239	LCK	Y116	P119S	119	Missense	distal	3	no	5.031	5.371	EPSD	COSMIC	5.050	Gain
TK_Src_SrcB_LCK_Y	P15311	EZR	P06239	LCK	Y291	R294H	294	Missense	distal	3	no	4.761	5.888	EPSD	COSMIC	5.050	Gain
TK_Src_SrcB_LCK_Y	P15311	EZR	P06239	LCK	Y478	P480L	480	Missense	proximal	2	no	6.042	4.868	EPSD	COSMIC	5.050	Loss
TK_Src_SrcB_LCK_Y	P42768	WAS	P06239	LCK	Y54	G60V	60	Missense	distal	6	no	6.238	6.170	EPSD	COSMIC	5.050	Down-regulation
TK_Src_SrcB_LCK_Y	P42768	WAS	P06239	LCK	Y54	P59L	59	Missense	distal	5	no	6.238	6.353	EPSD	COSMIC;GDSC;CCLE	5.050	Up-regulation
TK_Src_SrcB_LCK_Y	Q9UHD2	TBK1	P06239	LCK	Y185	D183G	183	Missense	proximal	-2	no	5.617	4.685	EPSD	COSMIC	5.050	Loss
TK_Src_SrcB_LCK_Y	Q9UHD2	TBK1	P06239	LCK	Y354	S347Y	347	Missense	distal	-7	no	6.710	6.509	PhosphoSitePlus;EPSD	COSMIC	5.050	Down-regulation
TK_Src_SrcB_LCK_Y	Q9UHD2	TBK1	P06239	LCK	Y354	R357Q	357	Missense	distal	3	no	6.710	6.728	PhosphoSitePlus;EPSD	COSMIC	5.050	Up-regulation
TK_Src_SrcB_LCK_Y	Q9UHD2	TBK1	P06239	LCK	Y394	S398F	398	Missense	distal	4	no	7.865	7.227	EPSD;PhosphoSitePlus	COSMIC	5.050	Down-regulation
TK_Src_SrcB_LCK_Y	Q9UHD2	TBK1	P06239	LCK	Y394	I390V	390	Missense	distal	-4	no	7.865	7.919	EPSD;PhosphoSitePlus	COSMIC	5.050	Up-regulation
TK_Src_SrcB_LCK_Y	Q9UN19	DAPP1	P06239	LCK	Y139	S137F	137	Missense	proximal	-2	no	9.733	9.166	PhosphoSitePlus	COSMIC	5.050	Down-regulation
TK_Src_SrcB_LCK_Y	Q9BZS1	FOXP3	P06239	LCK	Y342	A349S	349	Missense	distal	7	no	6.412	6.521	PhosphoSitePlus	COSMIC	5.050	Up-regulation
TK_Src_SrcB_LCK_Y	Q9BZS1	FOXP3	P06239	LCK	Y342	T344M	344	Missense	proximal	2	no	6.412	6.514	PhosphoSitePlus	COSMIC	5.050	Up-regulation
TK_Met_MST1R_Y	P08581	MET	Q04912	MST1R	Y971	Y971C	971	Missense	central	0	yes	0.001	0.000	EPSD	COSMIC	0.001	Loss
TK_Met_MST1R_Y	P08581	MET	Q04912	MST1R	Y1003	D1010H	1010	Missense	distal	7	no	0.001	0.000	EPSD	COSMIC	0.001	Loss
TK_Met_MST1R_Y	P08581	MET	Q04912	MST1R	Y1003	P1008A	1008	Missense	distal	5	no	0.001	0.000	EPSD	COSMIC	0.001	Loss
TK_Met_MST1R_Y	P08581	MET	Q04912	MST1R	Y1003	D1010N	1010	Missense	distal	7	no	0.001	0.000	EPSD	COSMIC	0.001	Loss
TK_Met_MST1R_Y	P08581	MET	Q04912	MST1R	Y1003	Y1003C	1003	Missense	central	0	yes	0.001	0.000	EPSD	COSMIC	0.001	Loss
TK_Met_MST1R_Y	P08581	MET	Q04912	MST1R	Y1003	V1001I	1001	Missense	proximal	-2	no	0.001	0.000	EPSD	COSMIC	0.001	Loss
TK_Met_MST1R_Y	P08581	MET	Q04912	MST1R	Y1003	Y1003N	1003	Missense	central	0	yes	0.001	0.000	EPSD	COSMIC	0.001	Loss
TK_Met_MST1R_Y	P08581	MET	Q04912	MST1R	Y1003	S1000F	1000	Missense	distal	-3	no	0.001	0.000	EPSD	COSMIC	0.001	Loss
TK_Met_MST1R_Y	P08581	MET	Q04912	MST1R	Y1003	Y1003S	1003	Missense	central	0	yes	0.001	0.000	EPSD	COSMIC	0.001	Loss
TK_Met_MST1R_Y	P08581	MET	Q04912	MST1R	Y1003	Y1003F	1003	Missense	central	0	yes	0.001	0.000	EPSD	COSMIC	0.001	Loss
TK_Met_MST1R_Y	P08581	MET	Q04912	MST1R	Y1003	E999K	999	Missense	distal	-4	no	0.001	0.000	EPSD	COSMIC	0.001	Loss
TK_Met_MST1R_Y	P08581	MET	Q04912	MST1R	Y1235	Y1235D	1235	Missense	central	0	yes	0.003	0.000	EPSD;PhosphoSitePlus	COSMIC	0.001	Loss
TK_Met_MST1R_Y	P08581	MET	Q04912	MST1R	Y1365	Y1365F	1365	Missense	central	0	yes	0.001	0.000	EPSD	COSMIC	0.001	Loss
TK_Ret_RET_Y	P40763	STAT3	Q15300	RET	Y539	W546L	546	Missense	distal	7	no	30.476	29.960	EPSD	COSMIC	28.094	Down-regulation
TK_Ret_RET_Y	P40763	STAT3	Q15300	RET	Y539	G541R	541	Missense	proximal	2	no	30.476	30.675	EPSD	COSMIC	28.094	Up-regulation
TK_Ret_RET_Y	P40763	STAT3	Q15300	RET	Y686	G684R	684	Missense	proximal	-2	no	28.945	33.223	EPSD	COSMIC	28.094	Up-regulation
TK_Ret_RET_Y	P40763	STAT3	Q15300	RET	Y686	F683L	683	Missense	distal	-3	no	28.945	29.908	EPSD	COSMIC	28.094	Up-regulation
Other_KIS_UHMK1_ST	Q15637	SF1	Q8TAS1	UHMK1	S80	S80Y	80	Missense	central	0	yes	4.656	0.000	PhosphoSitePlus;EPSD	COSMIC	1.522	Loss
Other_KIS_UHMK1_ST	Q15637	SF1	Q8TAS1	UHMK1	S80	S80F	80	Missense	central	0	yes	4.656	0.000	PhosphoSitePlus;EPSD	COSMIC	1.522	Loss
Other_KIS_UHMK1_ST	Q15637	SF1	Q8TAS1	UHMK1	S80	P81S	81	Missense	proximal	1	no	4.656	3.161	PhosphoSitePlus;EPSD	COSMIC	1.522	Down-regulation
Other_KIS_UHMK1_ST	Q15637	SF1	Q8TAS1	UHMK1	S80	P73L	73	Missense	distal	-7	no	4.656	4.354	PhosphoSitePlus;EPSD	COSMIC	1.522	Down-regulation
Other_KIS_UHMK1_ST	Q15637	SF1	Q8TAS1	UHMK1	S82	S80Y	80	Missense	proximal	-2	no	4.714	4.483	EPSD;PhosphoSitePlus	COSMIC	1.522	Down-regulation
Other_KIS_UHMK1_ST	Q15637	SF1	Q8TAS1	UHMK1	S82	S80F	80	Missense	proximal	-2	no	4.714	4.484	EPSD;PhosphoSitePlus	COSMIC	1.522	Down-regulation
Other_KIS_UHMK1_ST	Q15637	SF1	Q8TAS1	UHMK1	S82	P81S	81	Missense	proximal	-1	no	4.714	4.458	EPSD;PhosphoSitePlus	COSMIC	1.522	Down-regulation
Other_KIS_UHMK1_ST	Q15637	SF1	Q8TAS1	UHMK1	T232	E231K	231	Missense	proximal	-1	no	1.899	2.143	EPSD	COSMIC	1.522	Up-regulation
Other_KIS_UHMK1_ST	Q15637	SF1	Q8TAS1	UHMK1	T232	N237H	237	Missense	distal	5	no	1.899	1.897	EPSD	COSMIC	1.522	Down-regulation
Other_KIS_UHMK1_ST	Q15637	SF1	Q8TAS1	UHMK1	T232	P233A	233	Missense	proximal	1	no	1.899	0.134	EPSD	COSMIC	1.522	Loss
Other_KIS_UHMK1_ST	Q15637	SF1	Q8TAS1	UHMK1	T232	P233L	233	Missense	proximal	1	no	1.899	0.109	EPSD	COSMIC	1.522	Loss
Other_KIS_UHMK1_ST	Q15637	SF1	Q8TAS1	UHMK1	T232	D235E	235	Missense	distal	3	no	1.899	1.940	EPSD	COSMIC	1.522	Up-regulation
Other_KIS_UHMK1_ST	Q9BSJ6	PIMREG	Q8TAS1	UHMK1	S26	Q30R	30	Missense	distal	4	no	1.699	1.868	EPSD	COSMIC	1.522	Up-regulation
Other_KIS_UHMK1_ST	Q9BSJ6	PIMREG	Q8TAS1	UHMK1	S26	Q30H	30	Missense	distal	4	no	1.699	1.562	EPSD	COSMIC	1.522	Down-regulation
Other_KIS_UHMK1_ST	Q9BSJ6	PIMREG	Q8TAS1	UHMK1	S131	S137N	137	Missense	distal	6	no	4.212	4.237	PhosphoSitePlus	COSMIC	1.522	Up-regulation
Other_KIS_UHMK1_ST	Q9BSJ6	PIMREG	Q8TAS1	UHMK1	S131	A125V	125	Missense	distal	-6	no	4.212	4.236	PhosphoSitePlus	COSMIC	1.522	Up-regulation
Other_KIS_UHMK1_ST	Q9BSJ6	PIMREG	Q8TAS1	UHMK1	S131	S135N	135	Missense	distal	4	no	4.212	4.132	PhosphoSitePlus	COSMIC	1.522	Down-regulation
Other_KIS_UHMK1_ST	Q9BSJ6	PIMREG	Q8TAS1	UHMK1	S131	A125T	125	Missense	distal	-6	no	4.212	4.232	PhosphoSitePlus	COSMIC	1.522	Up-regulation
Other_KIS_UHMK1_ST	Q9BSJ6	PIMREG	Q8TAS1	UHMK1	S131	G124A	124	Missense	distal	-7	no	4.212	3.493	PhosphoSitePlus	COSMIC	1.522	Down-regulation
Other_KIS_UHMK1_ST	Q9BSJ6	PIMREG	Q8TAS1	UHMK1	S131	A125S	125	Missense	distal	-6	no	4.212	4.194	PhosphoSitePlus	COSMIC	1.522	Down-regulation
Other_KIS_UHMK1_ST	Q9BSJ6	PIMREG	Q8TAS1	UHMK1	S137	R142W	142	Missense	distal	5	no	1.970	1.920	EPSD	COSMIC	1.522	Down-regulation
Other_KIS_UHMK1_ST	Q9BSJ6	PIMREG	Q8TAS1	UHMK1	S137	S137N	137	Missense	central	0	yes	1.970	0.000	EPSD	COSMIC	1.522	Loss
Other_KIS_UHMK1_ST	Q9BSJ6	PIMREG	Q8TAS1	UHMK1	S137	S144P	144	Missense	distal	7	no	1.970	2.009	EPSD	COSMIC	1.522	Up-regulation
Other_KIS_UHMK1_ST	Q9BSJ6	PIMREG	Q8TAS1	UHMK1	S137	T141I	141	Missense	distal	4	no	1.970	1.986	EPSD	COSMIC	1.522	Up-regulation
Other_KIS_UHMK1_ST	Q9BSJ6	PIMREG	Q8TAS1	UHMK1	S137	S135N	135	Missense	proximal	-2	no	1.970	1.888	EPSD	COSMIC	1.522	Down-regulation
Other_KIS_UHMK1_ST	Q9BSJ6	PIMREG	Q8TAS1	UHMK1	S195	S199Y	199	Missense	distal	4	no	2.473	2.452	EPSD	COSMIC	1.522	Down-regulation
Other_KIS_UHMK1_ST	Q9BSJ6	PIMREG	Q8TAS1	UHMK1	S195	S197G	197	Missense	proximal	2	no	2.473	2.479	EPSD	COSMIC	1.522	Up-regulation
Other_KIS_UHMK1_ST	Q9BSJ6	PIMREG	Q8TAS1	UHMK1	S195	S188F	188	Missense	distal	-7	no	2.473	2.278	EPSD	COSMIC	1.522	Down-regulation
Other_KIS_UHMK1_ST	P46527	CDKN1B	Q8TAS1	UHMK1	S10	R5L	5	Missense	distal	-5	no	4.134	4.111	PhosphoSitePlus	COSMIC	1.522	Down-regulation
Other_KIS_UHMK1_ST	P46527	CDKN1B	Q8TAS1	UHMK1	S10	E14K	14	Missense	distal	4	no	4.134	4.282	PhosphoSitePlus	COSMIC	1.522	Up-regulation
Other_KIS_UHMK1_ST	P46527	CDKN1B	Q8TAS1	UHMK1	S10	M16T	16	Missense	distal	6	no	4.134	4.133	PhosphoSitePlus	COSMIC	1.522	Down-regulation
Other_KIS_UHMK1_ST	P46527	CDKN1B	Q8TAS1	UHMK1	S10	N3D	3	Missense	distal	-7	no	4.134	4.045	PhosphoSitePlus	COSMIC	1.522	Down-regulation
Other_KIS_UHMK1_ST	P46527	CDKN1B	Q8TAS1	UHMK1	S10	P11S	11	Missense	proximal	1	no	4.134	2.639	PhosphoSitePlus	COSMIC	1.522	Down-regulation
Other_KIS_UHMK1_ST	P46527	CDKN1B	Q8TAS1	UHMK1	S10	S12N	12	Missense	proximal	2	no	4.134	4.135	PhosphoSitePlus	COSMIC	1.522	Up-regulation
Other_KIS_UHMK1_ST	P46527	CDKN1B	Q8TAS1	UHMK1	S10	D17E	17	Missense	distal	7	no	4.134	4.125	PhosphoSitePlus	COSMIC	1.522	Down-regulation
Other_KIS_UHMK1_ST	P46527	CDKN1B	Q8TAS1	UHMK1	S83	W76G	76	Missense	distal	-7	no	1.366	1.882	EPSD	COSMIC	1.522	Gain
Other_KIS_UHMK1_ST	P46527	CDKN1B	Q8TAS1	UHMK1	S112	Q107R	107	Missense	distal	-5	no	1.641	1.643	EPSD	COSMIC	1.522	Up-regulation
Other_KIS_UHMK1_ST	P46527	CDKN1B	Q8TAS1	UHMK1	S112	D108N	108	Missense	distal	-4	no	1.641	1.654	EPSD	COSMIC	1.522	Up-regulation
Other_KIS_UHMK1_ST	P46527	CDKN1B	Q8TAS1	UHMK1	S112	A116T	116	Missense	distal	4	no	1.641	1.672	EPSD	COSMIC	1.522	Up-regulation
Other_KIS_UHMK1_ST	P46527	CDKN1B	Q8TAS1	UHMK1	S178	V184L	184	Missense	distal	6	no	1.784	1.811	EPSD	COSMIC	1.522	Up-regulation
Other_KIS_UHMK1_ST	P46527	CDKN1B	Q8TAS1	UHMK1	S178	G182D	182	Missense	distal	4	no	1.784	1.875	EPSD	COSMIC	1.522	Up-regulation
Other_KIS_UHMK1_ST	P16949	STMN1	Q8TAS1	UHMK1	S25	Q18E	18	Missense	distal	-7	no	2.925	2.840	EPSD	COSMIC	1.522	Down-regulation
Other_KIS_UHMK1_ST	P16949	STMN1	Q8TAS1	UHMK1	S38	D44N	44	Missense	distal	6	no	4.392	4.372	PhosphoSitePlus	COSMIC	1.522	Down-regulation
Other_KIS_UHMK1_ST	P16949	STMN1	Q8TAS1	UHMK1	S38	P36L	36	Missense	proximal	-2	no	4.392	4.214	PhosphoSitePlus	COSMIC	1.522	Down-regulation
Other_IKK_IKBKE_ST	Q96FA3	PELI1	Q14164	IKBKE	T117	D116H	116	Missense	proximal	-1	no	77.418	73.523	EPSD	COSMIC	71.554	Down-regulation
Other_IKK_IKBKE_ST	Q96FA3	PELI1	Q14164	IKBKE	T117	S123R	123	Missense	distal	6	no	77.418	75.059	EPSD	COSMIC	71.554	Down-regulation
Other_IKK_IKBKE_ST	Q96FA3	PELI1	Q14164	IKBKE	S125	S123R	123	Missense	proximal	-2	no	73.691	59.719	EPSD	COSMIC	71.554	Loss
Other_IKK_IKBKE_ST	Q96FA3	PELI1	Q14164	IKBKE	S129	S123R	123	Missense	distal	-6	no	79.238	78.310	EPSD	COSMIC	71.554	Down-regulation
Other_IKK_IKBKE_ST	Q96FA3	PELI1	Q14164	IKBKE	S293	R296K	296	Missense	distal	3	no	100.743	99.210	EPSD;PhosphoSitePlus	COSMIC	71.554	Down-regulation
Other_IKK_IKBKE_ST	O95644	NFATC1	Q14164	IKBKE	S117	P113S	113	Missense	distal	-4	no	97.976	99.763	EPSD;PhosphoSitePlus	COSMIC	71.554	Up-regulation
Other_IKK_IKBKE_ST	O95644	NFATC1	Q14164	IKBKE	S117	A112T	112	Missense	distal	-5	no	97.976	108.334	EPSD;PhosphoSitePlus	COSMIC	71.554	Up-regulation
Other_IKK_IKBKE_ST	O95644	NFATC1	Q14164	IKBKE	S117	P118L	118	Missense	proximal	1	no	97.976	101.358	EPSD;PhosphoSitePlus	COSMIC	71.554	Up-regulation
Other_IKK_IKBKE_ST	O95644	NFATC1	Q14164	IKBKE	S151	K149R	149	Missense	proximal	-2	no	95.414	85.201	EPSD;PhosphoSitePlus	COSMIC	71.554	Down-regulation
Other_IKK_IKBKE_ST	O95644	NFATC1	Q14164	IKBKE	S151	S153F	153	Missense	proximal	2	no	95.414	89.307	EPSD;PhosphoSitePlus	COSMIC	71.554	Down-regulation
Other_IKK_IKBKE_ST	O95644	NFATC1	Q14164	IKBKE	S161	D167H	167	Missense	distal	6	no	97.923	89.762	EPSD;PhosphoSitePlus	COSMIC	71.554	Down-regulation
Other_IKK_IKBKE_ST	O95644	NFATC1	Q14164	IKBKE	S233	S237P	237	Missense	distal	4	no	81.204	73.373	EPSD	COSMIC	71.554	Down-regulation
Other_IKK_IKBKE_ST	O95644	NFATC1	Q14164	IKBKE	S233	C228Y	228	Missense	distal	-5	no	81.204	93.864	EPSD	COSMIC	71.554	Up-regulation
Other_IKK_IKBKE_ST	O95644	NFATC1	Q14164	IKBKE	S233	S233F	233	Missense	central	0	yes	81.204	0.000	EPSD	COSMIC	71.554	Loss
Other_IKK_IKBKE_ST	O95644	NFATC1	Q14164	IKBKE	S233	R235W	235	Missense	proximal	2	no	81.204	75.018	EPSD	COSMIC	71.554	Down-regulation
Other_IKK_IKBKE_ST	O95644	NFATC1	Q14164	IKBKE	S241	S237P	237	Missense	distal	-4	no	79.048	77.261	EPSD	COSMIC	71.554	Down-regulation
Other_IKK_IKBKE_ST	O95644	NFATC1	Q14164	IKBKE	S241	R235W	235	Missense	distal	-6	no	79.048	83.796	EPSD	COSMIC	71.554	Up-regulation
Other_IKK_IKBKE_ST	O95644	NFATC1	Q14164	IKBKE	S245	E249K	249	Missense	distal	4	no	68.583	75.059	EPSD	COSMIC	71.554	Gain
Other_IKK_IKBKE_ST	O95644	NFATC1	Q14164	IKBKE	S257	A260T	260	Missense	distal	3	no	69.249	71.865	EPSD	COSMIC	71.554	Gain
Other_IKK_IKBKE_ST	O95644	NFATC1	Q14164	IKBKE	S257	R258I	258	Missense	proximal	1	no	69.249	75.429	EPSD	COSMIC	71.554	Gain
Other_IKK_IKBKE_ST	O95644	NFATC1	Q14164	IKBKE	S257	R255K	255	Missense	proximal	-2	no	69.249	79.463	EPSD	COSMIC	71.554	Gain
Other_IKK_IKBKE_ST	O95644	NFATC1	Q14164	IKBKE	S324	V331I	331	Missense	distal	7	no	96.624	98.379	PhosphoSitePlus;EPSD	COSMIC;CCLE	71.554	Up-regulation
Other_IKK_IKBKE_ST	O95644	NFATC1	Q14164	IKBKE	S324	A318V	318	Missense	distal	-6	no	96.624	96.053	PhosphoSitePlus;EPSD	COSMIC	71.554	Down-regulation
Other_IKK_IKBKE_ST	O95644	NFATC1	Q14164	IKBKE	S359	D365N	365	Missense	distal	6	no	78.484	71.293	EPSD	COSMIC	71.554	Loss
Other_IKK_IKBKE_ST	O95644	NFATC1	Q14164	IKBKE	S359	P363H	363	Missense	distal	4	no	78.484	66.414	EPSD	COSMIC	71.554	Loss
Other_IKK_IKBKE_ST	O95644	NFATC1	Q14164	IKBKE	S625	H619R	619	Missense	distal	-6	no	72.474	68.962	EPSD	COSMIC	71.554	Loss
Other_IKK_IKBKE_ST	O95644	NFATC1	Q14164	IKBKE	S723	R727K	727	Missense	distal	4	no	67.489	74.086	EPSD	COSMIC	71.554	Gain
Other_IKK_IKBKE_ST	O95644	NFATC1	Q14164	IKBKE	S765	A760T	760	Missense	distal	-5	no	61.964	72.322	EPSD	COSMIC	71.554	Gain
Other_IKK_IKBKE_ST	O95644	NFATC1	Q14164	IKBKE	S887	T881M	881	Missense	distal	-6	no	81.472	80.717	EPSD	COSMIC	71.554	Down-regulation
Other_IKK_IKBKE_ST	O95644	NFATC1	Q14164	IKBKE	S887	R893W	893	Missense	distal	6	no	81.472	77.981	EPSD	COSMIC	71.554	Down-regulation
Other_IKK_IKBKE_ST	O95644	NFATC1	Q14164	IKBKE	S887	R883H	883	Missense	distal	-4	no	81.472	75.554	EPSD	COSMIC	71.554	Down-regulation
Other_IKK_IKBKE_ST	O95644	NFATC1	Q14164	IKBKE	S887	A890V	890	Missense	distal	3	no	81.472	83.643	EPSD	COSMIC	71.554	Up-regulation
Other_IKK_IKBKE_ST	O95644	NFATC1	Q14164	IKBKE	S903	A907V	907	Missense	distal	4	no	72.002	72.445	EPSD	COSMIC	71.554	Up-regulation
Other_IKK_IKBKE_ST	P25963	NFKBIA	Q14164	IKBKE	S32	M37K	37	Missense	distal	5	no	107.210	108.438	EPSD;PhosphoSitePlus	COSMIC	71.554	Up-regulation
Other_IKK_IKBKE_ST	P25963	NFKBIA	Q14164	IKBKE	S32	S36P	36	Missense	distal	4	no	107.210	99.379	EPSD;PhosphoSitePlus	COSMIC	71.554	Down-regulation
Other_IKK_IKBKE_ST	P25963	NFKBIA	Q14164	IKBKE	S32	S32N	32	Missense	central	0	yes	107.210	0.000	EPSD;PhosphoSitePlus	COSMIC	71.554	Loss
Other_IKK_IKBKE_ST	P25963	NFKBIA	Q14164	IKBKE	S36	M37K	37	Missense	proximal	1	no	98.765	94.683	PhosphoSitePlus;EPSD	COSMIC	71.554	Down-regulation
Other_IKK_IKBKE_ST	P25963	NFKBIA	Q14164	IKBKE	S36	E40D	40	Missense	distal	4	no	98.765	95.453	PhosphoSitePlus;EPSD	COSMIC	71.554	Down-regulation
Other_IKK_IKBKE_ST	P25963	NFKBIA	Q14164	IKBKE	S36	E43K	43	Missense	distal	7	no	98.765	99.020	PhosphoSitePlus;EPSD	COSMIC	71.554	Up-regulation
Other_IKK_IKBKE_ST	P25963	NFKBIA	Q14164	IKBKE	S36	S36P	36	Missense	central	0	yes	98.765	0.000	PhosphoSitePlus;EPSD	COSMIC	71.554	Loss
Other_IKK_IKBKE_ST	P25963	NFKBIA	Q14164	IKBKE	S36	E43Q	43	Missense	distal	7	no	98.765	98.823	PhosphoSitePlus;EPSD	COSMIC	71.554	Up-regulation
Other_IKK_IKBKE_ST	P25963	NFKBIA	Q14164	IKBKE	S36	S32N	32	Missense	distal	-4	no	98.765	99.502	PhosphoSitePlus;EPSD	COSMIC	71.554	Up-regulation
Other_IKK_IKBKE_ST	P25963	NFKBIA	Q14164	IKBKE	S174	N180Y	180	Missense	distal	6	no	82.680	86.903	EPSD	COSMIC	71.554	Up-regulation
Other_IKK_IKBKE_ST	Q14653	IRF3	Q14164	IKBKE	T32	I36V	36	Missense	distal	4	no	60.057	87.809	EPSD	COSMIC	71.554	Gain
Other_IKK_IKBKE_ST	Q14653	IRF3	Q14164	IKBKE	S173	Q169R	169	Missense	distal	-4	no	69.829	73.783	EPSD	COSMIC;CCLE	71.554	Gain
Other_IKK_IKBKE_ST	Q14653	IRF3	Q14164	IKBKE	S175	Q169R	169	Missense	distal	-6	no	78.406	77.164	EPSD	COSMIC;CCLE	71.554	Down-regulation
Other_IKK_IKBKE_ST	Q14653	IRF3	Q14164	IKBKE	S339	G335E	335	Missense	distal	-4	no	73.411	75.602	EPSD	COSMIC	71.554	Up-regulation
Other_IKK_IKBKE_ST	Q14653	IRF3	Q14164	IKBKE	S339	R341C	341	Missense	proximal	2	no	73.411	72.823	EPSD	COSMIC	71.554	Down-regulation
Other_IKK_IKBKE_ST	Q14653	IRF3	Q14164	IKBKE	S339	G337A	337	Missense	proximal	-2	no	73.411	67.537	EPSD	COSMIC	71.554	Loss
Other_IKK_IKBKE_ST	Q14653	IRF3	Q14164	IKBKE	S339	G335V	335	Missense	distal	-4	no	73.411	73.720	EPSD	COSMIC	71.554	Up-regulation
Other_IKK_IKBKE_ST	Q14653	IRF3	Q14164	IKBKE	S386	R380W	380	Missense	distal	-6	no	95.767	100.515	PhosphoSitePlus;EPSD	COSMIC	71.554	Up-regulation
Other_IKK_IKBKE_ST	Q14653	IRF3	Q14164	IKBKE	S386	T390I	390	Missense	distal	4	no	95.767	65.706	PhosphoSitePlus;EPSD	COSMIC	71.554	Loss
Other_IKK_IKBKE_ST	Q14653	IRF3	Q14164	IKBKE	S386	T390P	390	Missense	distal	4	no	95.767	89.093	PhosphoSitePlus;EPSD	COSMIC	71.554	Down-regulation
Other_IKK_IKBKE_ST	Q14653	IRF3	Q14164	IKBKE	S386	E388D	388	Missense	proximal	2	no	95.767	90.842	PhosphoSitePlus;EPSD	COSMIC	71.554	Down-regulation
Other_IKK_IKBKE_ST	Q14653	IRF3	Q14164	IKBKE	S396	T390I	390	Missense	distal	-6	no	94.340	97.874	EPSD;PhosphoSitePlus	COSMIC	71.554	Up-regulation
Other_IKK_IKBKE_ST	Q14653	IRF3	Q14164	IKBKE	S396	T390P	390	Missense	distal	-6	no	94.340	94.500	EPSD;PhosphoSitePlus	COSMIC	71.554	Up-regulation
Other_IKK_IKBKE_ST	Q14653	IRF3	Q14164	IKBKE	S396	P400Q	400	Missense	distal	4	no	94.340	85.424	EPSD;PhosphoSitePlus	COSMIC	71.554	Down-regulation
Other_IKK_IKBKE_ST	Q14653	IRF3	Q14164	IKBKE	S396	P400T	400	Missense	distal	4	no	94.340	101.015	EPSD;PhosphoSitePlus	COSMIC	71.554	Up-regulation
Other_IKK_IKBKE_ST	Q14653	IRF3	Q14164	IKBKE	S398	P400Q	400	Missense	proximal	2	no	87.178	88.447	EPSD;PhosphoSitePlus	COSMIC	71.554	Up-regulation
Other_IKK_IKBKE_ST	Q14653	IRF3	Q14164	IKBKE	S398	P400T	400	Missense	proximal	2	no	87.178	91.481	EPSD;PhosphoSitePlus	COSMIC	71.554	Up-regulation
Other_IKK_IKBKE_ST	Q14653	IRF3	Q14164	IKBKE	S402	D406E	406	Missense	distal	4	no	78.525	81.837	EPSD;PhosphoSitePlus	COSMIC	71.554	Up-regulation
Other_IKK_IKBKE_ST	Q14653	IRF3	Q14164	IKBKE	S402	P400Q	400	Missense	proximal	-2	no	78.525	91.220	EPSD;PhosphoSitePlus	COSMIC	71.554	Up-regulation
Other_IKK_IKBKE_ST	Q14653	IRF3	Q14164	IKBKE	S402	P400T	400	Missense	proximal	-2	no	78.525	81.373	EPSD;PhosphoSitePlus	COSMIC	71.554	Up-regulation
Other_IKK_IKBKE_ST	P10914	IRF1	Q14164	IKBKE	S215	E222A	222	Missense	distal	7	no	94.464	94.919	EPSD;PhosphoSitePlus	COSMIC	71.554	Up-regulation
Other_IKK_IKBKE_ST	P10914	IRF1	Q14164	IKBKE	S215	S219F	219	Missense	distal	4	no	94.464	71.290	EPSD;PhosphoSitePlus	COSMIC	71.554	Loss
Other_IKK_IKBKE_ST	P10914	IRF1	Q14164	IKBKE	S215	Y210F	210	Missense	distal	-5	no	94.464	98.941	EPSD;PhosphoSitePlus	COSMIC;GDSC;CCLE	71.554	Up-regulation
Other_IKK_IKBKE_ST	P10914	IRF1	Q14164	IKBKE	S219	E222A	222	Missense	distal	3	no	99.613	95.461	PhosphoSitePlus;EPSD	COSMIC	71.554	Down-regulation
Other_IKK_IKBKE_ST	P10914	IRF1	Q14164	IKBKE	S219	S219F	219	Missense	central	0	yes	99.613	0.000	PhosphoSitePlus;EPSD	COSMIC	71.554	Loss
Other_IKK_IKBKE_ST	P10914	IRF1	Q14164	IKBKE	S221	E222A	222	Missense	proximal	1	no	95.211	84.693	EPSD;PhosphoSitePlus	COSMIC	71.554	Down-regulation
Other_IKK_IKBKE_ST	P10914	IRF1	Q14164	IKBKE	S221	S219F	219	Missense	proximal	-2	no	95.211	103.817	EPSD;PhosphoSitePlus	COSMIC	71.554	Up-regulation
Other_IKK_IKBKE_ST	Q92985	IRF7	Q14164	IKBKE	S125	R126L	126	Missense	proximal	1	no	62.294	74.600	EPSD	COSMIC	71.554	Gain
Other_IKK_IKBKE_ST	Q92985	IRF7	Q14164	IKBKE	S388	P392A	392	Missense	distal	4	no	77.810	81.732	EPSD	COSMIC	71.554	Up-regulation
Other_IKK_IKBKE_ST	Q92985	IRF7	Q14164	IKBKE	S388	G382R	382	Missense	distal	-6	no	77.810	75.726	EPSD	COSMIC	71.554	Down-regulation
Other_IKK_IKBKE_ST	Q92985	IRF7	Q14164	IKBKE	S388	S386F	386	Missense	proximal	-2	no	77.810	86.416	EPSD	COSMIC	71.554	Up-regulation
Other_IKK_IKBKE_ST	Q92985	IRF7	Q14164	IKBKE	S388	S386Y	386	Missense	proximal	-2	no	77.810	65.640	EPSD	COSMIC	71.554	Loss
Other_IKK_IKBKE_ST	Q92985	IRF7	Q14164	IKBKE	S471	S471N	471	Missense	central	0	yes	96.452	0.000	EPSD;PhosphoSitePlus	COSMIC	71.554	Loss
Other_IKK_IKBKE_ST	Q92985	IRF7	Q14164	IKBKE	S472	S471N	471	Missense	proximal	-1	no	103.179	102.518	EPSD;PhosphoSitePlus	COSMIC	71.554	Down-regulation
Other_IKK_IKBKE_ST	Q92985	IRF7	Q14164	IKBKE	S477	S484F	484	Missense	distal	7	no	94.759	95.646	PhosphoSitePlus;EPSD	COSMIC	71.554	Up-regulation
Other_IKK_IKBKE_ST	Q92985	IRF7	Q14164	IKBKE	S477	S471N	471	Missense	distal	-6	no	94.759	95.920	PhosphoSitePlus;EPSD	COSMIC	71.554	Up-regulation
Other_IKK_IKBKE_ST	Q92985	IRF7	Q14164	IKBKE	S479	S484F	484	Missense	distal	5	no	85.941	87.496	EPSD;PhosphoSitePlus	COSMIC	71.554	Up-regulation
Other_IKK_IKBKE_ST	Q12933	TRAF2	Q14164	IKBKE	S102	R97H	97	Missense	distal	-5	no	76.608	75.365	EPSD	COSMIC	71.554	Down-regulation
Other_IKK_IKBKE_ST	Q12933	TRAF2	Q14164	IKBKE	S102	A105T	105	Missense	distal	3	no	76.608	79.224	EPSD	COSMIC;GDSC;CCLE	71.554	Up-regulation
Other_IKK_IKBKE_ST	Q12933	TRAF2	Q14164	IKBKE	S102	P104L	104	Missense	proximal	2	no	76.608	75.005	EPSD	COSMIC;GDSC;CCLE	71.554	Down-regulation
Other_IKK_IKBKE_ST	O95786	DDX58	Q14164	IKBKE	S8	R6Q	6	Missense	proximal	-2	no	58.102	78.640	EPSD	COSMIC	71.554	Gain
Other_IKK_IKBKE_ST	O95786	DDX58	Q14164	IKBKE	S484	A486V	486	Missense	proximal	2	no	69.153	73.671	EPSD	COSMIC	71.554	Gain
Other_IKK_IKBKE_ST	O95786	DDX58	Q14164	IKBKE	S855	P850Q	850	Missense	distal	-5	no	99.185	93.789	PhosphoSitePlus	COSMIC	71.554	Down-regulation
Other_IKK_IKBKE_ST	O95786	DDX58	Q14164	IKBKE	S855	K858R	858	Missense	distal	3	no	99.185	100.718	PhosphoSitePlus	COSMIC	71.554	Up-regulation
Other_IKK_IKBKE_ST	O95786	DDX58	Q14164	IKBKE	S855	R859G	859	Missense	distal	4	no	99.185	102.825	PhosphoSitePlus	COSMIC	71.554	Up-regulation
Other_IKK_IKBKE_ST	P03372	ESR1	Q14164	IKBKE	T7	H6Y	6	Missense	proximal	-1	no	70.825	73.194	EPSD	COSMIC;GDSC	71.554	Gain
Other_IKK_IKBKE_ST	P03372	ESR1	Q14164	IKBKE	T7	G11S	11	Missense	distal	4	no	70.825	78.471	EPSD	COSMIC	71.554	Gain
Other_IKK_IKBKE_ST	P03372	ESR1	Q14164	IKBKE	S46	S47T	47	Missense	proximal	1	no	76.917	70.649	EPSD	COSMIC	71.554	Loss
Other_IKK_IKBKE_ST	P03372	ESR1	Q14164	IKBKE	S46	A50T	50	Missense	distal	4	no	76.917	79.670	EPSD	COSMIC	71.554	Up-regulation
Other_IKK_IKBKE_ST	P03372	ESR1	Q14164	IKBKE	S46	K48N	48	Missense	proximal	2	no	76.917	78.122	EPSD	COSMIC	71.554	Up-regulation
Other_IKK_IKBKE_ST	P03372	ESR1	Q14164	IKBKE	S46	D45N	45	Missense	proximal	-1	no	76.917	75.712	EPSD	COSMIC	71.554	Down-regulation
Other_IKK_IKBKE_ST	P03372	ESR1	Q14164	IKBKE	S46	P49S	49	Missense	distal	3	no	76.917	76.886	EPSD	COSMIC	71.554	Down-regulation
Other_IKK_IKBKE_ST	P03372	ESR1	Q14164	IKBKE	S104	F97L	97	Missense	distal	-7	no	81.324	80.808	EPSD	COSMIC	71.554	Down-regulation
Other_IKK_IKBKE_ST	P03372	ESR1	Q14164	IKBKE	S104	M109T	109	Missense	distal	5	no	81.324	81.593	EPSD	COSMIC	71.554	Up-regulation
Other_IKK_IKBKE_ST	P03372	ESR1	Q14164	IKBKE	S167	G172R	172	Missense	distal	5	no	96.639	98.217	PhosphoSitePlus	COSMIC	71.554	Up-regulation
Other_IKK_IKBKE_ST	P03372	ESR1	Q14164	IKBKE	S167	M174I	174	Missense	distal	7	no	96.639	98.809	PhosphoSitePlus	COSMIC	71.554	Up-regulation
Other_IKK_IKBKE_ST	P03372	ESR1	Q14164	IKBKE	S167	D170Y	170	Missense	distal	3	no	96.639	95.272	PhosphoSitePlus	COSMIC	71.554	Down-regulation
Other_IKK_IKBKE_ST	P03372	ESR1	Q14164	IKBKE	S167	G160D	160	Missense	distal	-7	no	96.639	95.568	PhosphoSitePlus	COSMIC	71.554	Down-regulation
Other_IKK_IKBKE_ST	P03372	ESR1	Q14164	IKBKE	S305	N304S	304	Missense	proximal	-1	no	71.296	71.956	EPSD	COSMIC	71.554	Gain
Other_IKK_IKBKE_ST	P31749	AKT1	Q14164	IKBKE	S122	E115K	115	Missense	distal	-7	no	80.079	81.405	EPSD	COSMIC	71.554	Up-regulation
Other_IKK_IKBKE_ST	P31749	AKT1	Q14164	IKBKE	S122	G123D	123	Missense	proximal	1	no	80.079	81.074	EPSD	COSMIC	71.554	Up-regulation
Other_IKK_IKBKE_ST	P31749	AKT1	Q14164	IKBKE	S122	D127N	127	Missense	distal	5	no	80.079	80.578	EPSD	COSMIC	71.554	Up-regulation
Other_IKK_IKBKE_ST	P31749	AKT1	Q14164	IKBKE	S122	E116D	116	Missense	distal	-6	no	80.079	81.109	EPSD	COSMIC	71.554	Up-regulation
Other_IKK_IKBKE_ST	P31749	AKT1	Q14164	IKBKE	S124	G123D	123	Missense	proximal	-1	no	69.806	73.488	EPSD	COSMIC	71.554	Gain
Other_IKK_IKBKE_ST	P31749	AKT1	Q14164	IKBKE	S137	E135Q	135	Missense	proximal	-2	no	59.855	75.871	EPSD	COSMIC	71.554	Gain
Other_IKK_IKBKE_ST	P31749	AKT1	Q14164	IKBKE	T308	M306T	306	Missense	proximal	-2	no	94.602	85.237	EPSD;PhosphoSitePlus	COSMIC	71.554	Down-regulation
Other_IKK_IKBKE_ST	P31749	AKT1	Q14164	IKBKE	T308	M306L	306	Missense	proximal	-2	no	94.602	95.148	EPSD;PhosphoSitePlus	COSMIC	71.554	Up-regulation
Other_IKK_IKBKE_ST	P31749	AKT1	Q14164	IKBKE	T308	M306I	306	Missense	proximal	-2	no	94.602	82.838	EPSD;PhosphoSitePlus	COSMIC	71.554	Down-regulation
Other_IKK_IKBKE_ST	P31749	AKT1	Q14164	IKBKE	T308	T312I	312	Missense	distal	4	no	94.602	64.541	EPSD;PhosphoSitePlus	COSMIC	71.554	Loss
Other_IKK_IKBKE_ST	P31749	AKT1	Q14164	IKBKE	T308	G303S	303	Missense	distal	-5	no	94.602	93.439	EPSD;PhosphoSitePlus	COSMIC	71.554	Down-regulation
Other_IKK_IKBKE_ST	P31749	AKT1	Q14164	IKBKE	S378	G373D	373	Missense	distal	-5	no	77.927	83.493	EPSD	COSMIC	71.554	Up-regulation
Other_IKK_IKBKE_ST	P31749	AKT1	Q14164	IKBKE	S378	S378F	378	Missense	central	0	yes	77.927	0.000	EPSD	COSMIC	71.554	Loss
Other_IKK_IKBKE_ST	P31749	AKT1	Q14164	IKBKE	S378	P374T	374	Missense	distal	-4	no	77.927	80.643	EPSD	COSMIC	71.554	Up-regulation
Other_IKK_IKBKE_ST	P31749	AKT1	Q14164	IKBKE	S378	S378C	378	Missense	central	0	yes	77.927	0.000	EPSD	COSMIC	71.554	Loss
Other_IKK_IKBKE_ST	P31749	AKT1	Q14164	IKBKE	S378	S381L	381	Missense	distal	3	no	77.927	77.271	EPSD	COSMIC	71.554	Down-regulation
Other_IKK_IKBKE_ST	P31749	AKT1	Q14164	IKBKE	S473	S477N	477	Missense	distal	4	no	82.406	61.170	PhosphoSitePlus;EPSD	COSMIC	71.554	Loss
Other_IKK_IKBKE_ST	P31749	AKT1	Q14164	IKBKE	S473	P470L	470	Missense	distal	-3	no	82.406	82.781	PhosphoSitePlus;EPSD	COSMIC	71.554	Up-regulation
Other_IKK_IKBKE_ST	O14519	CDK2AP1	Q14164	IKBKE	S28	H23R	23	Missense	distal	-5	no	79.825	81.068	EPSD	COSMIC	71.554	Up-regulation
Other_IKK_IKBKE_ST	O14519	CDK2AP1	Q14164	IKBKE	S28	T31M	31	Missense	distal	3	no	79.825	78.988	EPSD	COSMIC	71.554	Down-regulation
Other_IKK_IKBKE_ST	O14519	CDK2AP1	Q14164	IKBKE	S28	S32T	32	Missense	distal	4	no	79.825	78.669	EPSD	COSMIC	71.554	Down-regulation
Other_IKK_IKBKE_ST	O14519	CDK2AP1	Q14164	IKBKE	S46	Y49H	49	Missense	distal	3	no	100.574	99.980	PhosphoSitePlus	COSMIC	71.554	Down-regulation
Other_IKK_IKBKE_ST	O14519	CDK2AP1	Q14164	IKBKE	S46	L47P	47	Missense	proximal	1	no	100.574	97.192	PhosphoSitePlus	COSMIC	71.554	Down-regulation
Other_IKK_IKBKE_ST	P98170	XIAP	Q14164	IKBKE	S5	G8R	8	Missense	distal	3	no	96.387	97.470	EPSD	COSMIC	71.554	Up-regulation
Other_IKK_IKBKE_ST	P98170	XIAP	Q14164	IKBKE	S38	G39D	39	Missense	proximal	1	no	76.505	77.500	EPSD	COSMIC	71.554	Up-regulation
Other_IKK_IKBKE_ST	P98170	XIAP	Q14164	IKBKE	S40	G39D	39	Missense	proximal	-1	no	76.542	80.225	EPSD	COSMIC	71.554	Up-regulation
Other_IKK_IKBKE_ST	P98170	XIAP	Q14164	IKBKE	S347	H343N	343	Missense	distal	-4	no	77.785	81.897	EPSD	COSMIC	71.554	Up-regulation
Other_IKK_IKBKE_ST	P98170	XIAP	Q14164	IKBKE	S347	V353A	353	Missense	distal	6	no	77.785	80.573	EPSD	COSMIC	71.554	Up-regulation
Other_IKK_IKBKE_ST	P98170	XIAP	Q14164	IKBKE	S347	N340H	340	Missense	distal	-7	no	77.785	78.657	EPSD	COSMIC	71.554	Up-regulation
Other_IKK_IKBKE_ST	P98170	XIAP	Q14164	IKBKE	S430	T437I	437	Missense	distal	7	no	98.479	100.668	PhosphoSitePlus	COSMIC;GDSC;CCLE	71.554	Up-regulation
Other_IKK_IKBKE_ST	P98170	XIAP	Q14164	IKBKE	S430	Q432H	432	Missense	proximal	2	no	98.479	95.247	PhosphoSitePlus	COSMIC	71.554	Down-regulation
Other_IKK_IKBKE_ST	P98170	XIAP	Q14164	IKBKE	S430	S430L	430	Missense	central	0	yes	98.479	0.000	PhosphoSitePlus	COSMIC	71.554	Loss
Other_IKK_IKBKE_ST	P46937	YAP1	Q14164	IKBKE	S103	R106G	106	Missense	distal	3	no	77.490	76.407	EPSD	COSMIC	71.554	Down-regulation
Other_IKK_IKBKE_ST	P46937	YAP1	Q14164	IKBKE	S103	S105P	105	Missense	proximal	2	no	77.490	72.846	EPSD	COSMIC	71.554	Down-regulation
Other_IKK_IKBKE_ST	P46937	YAP1	Q14164	IKBKE	S103	K102R	102	Missense	proximal	-1	no	77.490	84.445	EPSD	COSMIC	71.554	Up-regulation
Other_IKK_IKBKE_ST	P46937	YAP1	Q14164	IKBKE	S138	P139F	139	Missense	proximal	1	no	69.049	74.705	EPSD	COSMIC	71.554	Gain
Other_IKK_IKBKE_ST	P46937	YAP1	Q14164	IKBKE	S138	Q133H	133	Missense	distal	-5	no	69.049	72.206	EPSD	COSMIC	71.554	Gain
Other_IKK_IKBKE_ST	P46937	YAP1	Q14164	IKBKE	S149	A152T	152	Missense	distal	3	no	78.232	80.848	EPSD	COSMIC	71.554	Up-regulation
Other_IKK_IKBKE_ST	P46937	YAP1	Q14164	IKBKE	S149	T145S	145	Missense	distal	-4	no	78.232	77.303	EPSD	COSMIC	71.554	Down-regulation
Other_IKK_IKBKE_ST	P46937	YAP1	Q14164	IKBKE	S149	P151A	151	Missense	proximal	2	no	78.232	78.600	EPSD	COSMIC	71.554	Up-regulation
Other_IKK_IKBKE_ST	P46937	YAP1	Q14164	IKBKE	S164	D170N	170	Missense	distal	6	no	81.450	74.259	EPSD	COSMIC	71.554	Down-regulation
Other_IKK_IKBKE_ST	P46937	YAP1	Q14164	IKBKE	S164	I167T	167	Missense	distal	3	no	81.450	82.701	EPSD	COSMIC	71.554	Up-regulation
Other_IKK_IKBKE_ST	P46937	YAP1	Q14164	IKBKE	S164	Q162R	162	Missense	proximal	-2	no	81.450	60.912	EPSD	COSMIC	71.554	Loss
Other_IKK_IKBKE_ST	P46937	YAP1	Q14164	IKBKE	S164	L160H	160	Missense	distal	-4	no	81.450	80.101	EPSD	COSMIC	71.554	Down-regulation
Other_IKK_IKBKE_ST	P46937	YAP1	Q14164	IKBKE	S164	E166G	166	Missense	proximal	2	no	81.450	79.747	EPSD	COSMIC	71.554	Down-regulation
Other_IKK_IKBKE_ST	P46937	YAP1	Q14164	IKBKE	S183	A180T	180	Missense	distal	-3	no	74.528	78.084	EPSD	COSMIC	71.554	Up-regulation
Other_IKK_IKBKE_ST	P46937	YAP1	Q14164	IKBKE	T216	Q209L	209	Missense	distal	-7	no	74.560	74.884	EPSD	COSMIC	71.554	Up-regulation
Other_IKK_IKBKE_ST	P46937	YAP1	Q14164	IKBKE	T216	V212I	212	Missense	distal	-4	no	74.560	69.049	EPSD	COSMIC	71.554	Loss
Other_IKK_IKBKE_ST	P46937	YAP1	Q14164	IKBKE	T216	M210I	210	Missense	distal	-6	no	74.560	78.848	EPSD	COSMIC	71.554	Up-regulation
Other_IKK_IKBKE_ST	P46937	YAP1	Q14164	IKBKE	S350	L352P	352	Missense	proximal	2	no	76.931	78.534	EPSD	COSMIC	71.554	Up-regulation
Other_IKK_IKBKE_ST	P46937	YAP1	Q14164	IKBKE	S350	L348P	348	Missense	proximal	-2	no	76.931	64.172	EPSD	COSMIC	71.554	Loss
Other_IKK_IKBKE_ST	P46937	YAP1	Q14164	IKBKE	S366	S367F	367	Missense	proximal	1	no	69.936	79.241	EPSD	COSMIC	71.554	Gain
Other_IKK_IKBKE_ST	P46937	YAP1	Q14164	IKBKE	S406	D399G	399	Missense	distal	-7	no	75.332	76.403	EPSD	COSMIC	71.554	Up-regulation
Other_IKK_IKBKE_ST	P46937	YAP1	Q14164	IKBKE	S406	D399H	399	Missense	distal	-7	no	75.332	76.631	EPSD	COSMIC	71.554	Up-regulation
Other_IKK_IKBKE_ST	P46937	YAP1	Q14164	IKBKE	S406	R411Q	411	Missense	distal	5	no	75.332	74.783	EPSD	COSMIC	71.554	Down-regulation
Other_IKK_IKBKE_ST	P46937	YAP1	Q14164	IKBKE	S419	N418T	418	Missense	proximal	-1	no	104.296	105.984	PhosphoSitePlus	COSMIC	71.554	Up-regulation
Other_IKK_IKBKE_ST	P46937	YAP1	Q14164	IKBKE	S419	F416L	416	Missense	distal	-3	no	104.296	106.094	PhosphoSitePlus	COSMIC	71.554	Up-regulation
Other_IKK_IKBKE_ST	P46937	YAP1	Q14164	IKBKE	S432	I429L	429	Missense	distal	-3	no	70.578	71.742	EPSD	COSMIC	71.554	Gain
Other_IKK_IKBKE_ST	O00571	DDX3X	Q14164	IKBKE	S74	G73R	73	Missense	proximal	-1	no	69.925	76.468	EPSD	COSMIC	71.554	Gain
Other_IKK_IKBKE_ST	O00571	DDX3X	Q14164	IKBKE	S86	R79K	79	Missense	distal	-7	no	74.019	75.259	EPSD	COSMIC	71.554	Up-regulation
Other_IKK_IKBKE_ST	O00571	DDX3X	Q14164	IKBKE	S86	R88C	88	Missense	proximal	2	no	74.019	73.431	EPSD	COSMIC	71.554	Down-regulation
Other_IKK_IKBKE_ST	O00571	DDX3X	Q14164	IKBKE	S86	R93K	93	Missense	distal	7	no	74.019	75.017	EPSD	COSMIC	71.554	Up-regulation
Other_IKK_IKBKE_ST	O00571	DDX3X	Q14164	IKBKE	S86	G89R	89	Missense	distal	3	no	74.019	75.102	EPSD	COSMIC	71.554	Up-regulation
Other_IKK_IKBKE_ST	O00571	DDX3X	Q14164	IKBKE	S86	S86C	86	Missense	central	0	yes	74.019	0.000	EPSD	COSMIC	71.554	Loss
Other_IKK_IKBKE_ST	O00571	DDX3X	Q14164	IKBKE	S90	R88C	88	Missense	proximal	-2	no	72.316	65.369	EPSD	COSMIC	71.554	Loss
Other_IKK_IKBKE_ST	O00571	DDX3X	Q14164	IKBKE	S90	R93K	93	Missense	distal	3	no	72.316	70.783	EPSD	COSMIC	71.554	Loss
Other_IKK_IKBKE_ST	O00571	DDX3X	Q14164	IKBKE	S90	G89R	89	Missense	proximal	-1	no	72.316	78.860	EPSD	COSMIC	71.554	Up-regulation
Other_IKK_IKBKE_ST	O00571	DDX3X	Q14164	IKBKE	S90	G94D	94	Missense	distal	4	no	72.316	65.486	EPSD	COSMIC	71.554	Loss
Other_IKK_IKBKE_ST	O00571	DDX3X	Q14164	IKBKE	S90	S86C	86	Missense	distal	-4	no	72.316	68.243	EPSD	COSMIC	71.554	Loss
Other_IKK_IKBKE_ST	O00571	DDX3X	Q14164	IKBKE	S102	S109C	109	Missense	distal	7	no	98.722	99.816	PhosphoSitePlus	COSMIC	71.554	Up-regulation
Other_IKK_IKBKE_ST	O00571	DDX3X	Q14164	IKBKE	S102	R99T	99	Missense	distal	-3	no	98.722	99.349	PhosphoSitePlus	COSMIC	71.554	Up-regulation
Other_IKK_IKBKE_ST	O00571	DDX3X	Q14164	IKBKE	S109	R113T	113	Missense	distal	4	no	62.472	72.600	EPSD	COSMIC	71.554	Gain
Other_IKK_IKBKE_ST	O00571	DDX3X	Q14164	IKBKE	S114	R113T	113	Missense	proximal	-1	no	77.913	75.536	EPSD	COSMIC	71.554	Down-regulation
Other_IKK_IKBKE_ST	O00571	DDX3X	Q14164	IKBKE	S114	R110S	110	Missense	distal	-4	no	77.913	75.371	EPSD	COSMIC	71.554	Down-regulation
Other_IKK_IKBKE_ST	O00571	DDX3X	Q14164	IKBKE	S114	R121C	121	Missense	distal	7	no	77.913	79.531	EPSD	COSMIC	71.554	Up-regulation
Other_IKK_IKBKE_ST	O00571	DDX3X	Q14164	IKBKE	S114	R110P	110	Missense	distal	-4	no	77.913	73.583	EPSD	COSMIC	71.554	Down-regulation
Other_IKK_IKBKE_ST	O00571	DDX3X	Q14164	IKBKE	S114	S109C	109	Missense	distal	-5	no	77.913	67.108	EPSD	COSMIC	71.554	Loss
Other_IKK_IKBKE_ST	O00571	DDX3X	Q14164	IKBKE	S114	G117D	117	Missense	distal	3	no	77.913	78.700	EPSD	COSMIC	71.554	Up-regulation
Other_IKK_IKBKE_ST	O00571	DDX3X	Q14164	IKBKE	S114	G115D	115	Missense	proximal	1	no	77.913	78.909	EPSD	COSMIC	71.554	Up-regulation
Other_IKK_IKBKE_ST	O00571	DDX3X	Q14164	IKBKE	S183	I179T	179	Missense	distal	-4	no	70.188	76.773	EPSD	COSMIC	71.554	Gain
Other_IKK_IKBKE_ST	O00571	DDX3X	Q14164	IKBKE	S269	T275P	275	Missense	distal	6	no	79.021	75.273	EPSD	COSMIC	71.554	Down-regulation
Other_IKK_IKBKE_ST	O00571	DDX3X	Q14164	IKBKE	S269	A273T	273	Missense	distal	4	no	79.021	81.774	EPSD	COSMIC	71.554	Up-regulation
Other_IKK_IKBKE_ST	O00571	DDX3X	Q14164	IKBKE	S269	R276K	276	Missense	distal	7	no	79.021	80.020	EPSD	COSMIC	71.554	Up-regulation
Other_IKK_IKBKE_ST	O00571	DDX3X	Q14164	IKBKE	S269	R276L	276	Missense	distal	7	no	79.021	80.328	EPSD	COSMIC	71.554	Up-regulation
Other_IKK_IKBKE_ST	O00571	DDX3X	Q14164	IKBKE	S269	R276Q	276	Missense	distal	7	no	79.021	79.823	EPSD	COSMIC	71.554	Up-regulation
Other_IKK_IKBKE_ST	O00571	DDX3X	Q14164	IKBKE	S269	Q265H	265	Missense	distal	-4	no	79.021	77.058	EPSD	COSMIC	71.554	Down-regulation
Other_IKK_IKBKE_ST	O00571	DDX3X	Q14164	IKBKE	S269	R262K	262	Missense	distal	-7	no	79.021	80.262	EPSD	COSMIC	71.554	Up-regulation
Other_IKK_IKBKE_ST	O00571	DDX3X	Q14164	IKBKE	S269	R276C	276	Missense	distal	7	no	79.021	80.639	EPSD	COSMIC	71.554	Up-regulation
Other_IKK_IKBKE_ST	O00571	DDX3X	Q14164	IKBKE	S269	R276H	276	Missense	distal	7	no	79.021	81.152	EPSD	COSMIC	71.554	Up-regulation
Other_IKK_IKBKE_ST	O00571	DDX3X	Q14164	IKBKE	S382	A383P	383	Missense	proximal	1	no	55.402	73.286	EPSD	COSMIC;GDSC;CCLE	71.554	Gain
Other_IKK_IKBKE_ST	O00571	DDX3X	Q14164	IKBKE	T438	A437E	437	Missense	proximal	-1	no	74.598	77.816	EPSD	COSMIC	71.554	Up-regulation
Other_IKK_IKBKE_ST	O00571	DDX3X	Q14164	IKBKE	T438	L443V	443	Missense	distal	5	no	74.598	74.579	EPSD	COSMIC	71.554	Down-regulation
Other_IKK_IKBKE_ST	O00571	DDX3X	Q14164	IKBKE	T438	L431R	431	Missense	distal	-7	no	74.598	73.221	EPSD	COSMIC	71.554	Down-regulation
Other_IKK_IKBKE_ST	O00571	DDX3X	Q14164	IKBKE	T438	G439R	439	Missense	proximal	1	no	74.598	80.260	EPSD	COSMIC	71.554	Up-regulation
Other_IKK_IKBKE_ST	O00571	DDX3X	Q14164	IKBKE	T438	G439S	439	Missense	proximal	1	no	74.598	85.535	EPSD	COSMIC	71.554	Up-regulation
Other_IKK_IKBKE_ST	O00571	DDX3X	Q14164	IKBKE	T438	L443Q	443	Missense	distal	5	no	74.598	75.822	EPSD	COSMIC	71.554	Up-regulation
Other_IKK_IKBKE_ST	O00571	DDX3X	Q14164	IKBKE	T438	D441Y	441	Missense	distal	3	no	74.598	73.231	EPSD	COSMIC	71.554	Down-regulation
Other_IKK_IKBKE_ST	O00571	DDX3X	Q14164	IKBKE	T438	T438P	438	Missense	central	0	yes	74.598	0.000	EPSD	COSMIC	71.554	Loss
Other_IKK_IKBKE_ST	O00571	DDX3X	Q14164	IKBKE	T438	A437P	437	Missense	proximal	-1	no	74.598	77.398	EPSD	COSMIC	71.554	Up-regulation
Other_IKK_IKBKE_ST	O00571	DDX3X	Q14164	IKBKE	T438	A437T	437	Missense	proximal	-1	no	74.598	77.827	EPSD	COSMIC	71.554	Up-regulation
Other_IKK_IKBKE_ST	O00571	DDX3X	Q14164	IKBKE	S489	A483G	483	Missense	distal	-6	no	71.722	70.899	EPSD	COSMIC	71.554	Loss
Other_IKK_IKBKE_ST	O00571	DDX3X	Q14164	IKBKE	S489	G490V	490	Missense	proximal	1	no	71.722	81.283	EPSD	COSMIC	71.554	Up-regulation
Other_IKK_IKBKE_ST	O00571	DDX3X	Q14164	IKBKE	S489	R488H	488	Missense	proximal	-1	no	71.722	64.966	EPSD	COSMIC	71.554	Loss
Other_IKK_IKBKE_ST	O00571	DDX3X	Q14164	IKBKE	S489	G490E	490	Missense	proximal	1	no	71.722	78.943	EPSD	COSMIC	71.554	Up-regulation
Other_IKK_IKBKE_ST	O00571	DDX3X	Q14164	IKBKE	S489	F487I	487	Missense	proximal	-2	no	71.722	57.437	EPSD	COSMIC	71.554	Loss
Other_IKK_IKBKE_ST	O00571	DDX3X	Q14164	IKBKE	S489	S492L	492	Missense	distal	3	no	71.722	71.066	EPSD	COSMIC	71.554	Loss
Other_IKK_IKBKE_ST	O00571	DDX3X	Q14164	IKBKE	S492	G490V	490	Missense	proximal	-2	no	75.194	72.375	EPSD	COSMIC	71.554	Down-regulation
Other_IKK_IKBKE_ST	O00571	DDX3X	Q14164	IKBKE	S492	R488H	488	Missense	distal	-4	no	75.194	69.277	EPSD	COSMIC	71.554	Loss
Other_IKK_IKBKE_ST	O00571	DDX3X	Q14164	IKBKE	S492	G490E	490	Missense	proximal	-2	no	75.194	66.479	EPSD	COSMIC	71.554	Loss
Other_IKK_IKBKE_ST	O00571	DDX3X	Q14164	IKBKE	S492	T498A	498	Missense	distal	6	no	75.194	73.365	EPSD	COSMIC	71.554	Down-regulation
Other_IKK_IKBKE_ST	O00571	DDX3X	Q14164	IKBKE	S492	F487I	487	Missense	distal	-5	no	75.194	72.771	EPSD	COSMIC	71.554	Down-regulation
Other_IKK_IKBKE_ST	O00571	DDX3X	Q14164	IKBKE	S492	S492L	492	Missense	central	0	yes	75.194	0.000	EPSD	COSMIC	71.554	Loss
Other_IKK_IKBKE_ST	O00571	DDX3X	Q14164	IKBKE	S520	E523K	523	Missense	distal	3	no	83.612	81.323	EPSD	COSMIC	71.554	Down-regulation
Other_IKK_IKBKE_ST	O00571	DDX3X	Q14164	IKBKE	S520	N515D	515	Missense	distal	-5	no	83.612	82.827	EPSD	COSMIC	71.554	Down-regulation
Other_IKK_IKBKE_ST	O00571	DDX3X	Q14164	IKBKE	S520	E524K	524	Missense	distal	4	no	83.612	90.088	EPSD	COSMIC	71.554	Up-regulation
Other_IKK_IKBKE_ST	O00571	DDX3X	Q14164	IKBKE	S606	G607R	607	Missense	proximal	1	no	66.429	72.091	EPSD	COSMIC	71.554	Gain
Other_IKK_IKBKE_ST	O00571	DDX3X	Q14164	IKBKE	S610	S609Y	609	Missense	proximal	-1	no	72.289	71.307	EPSD	COSMIC	71.554	Loss
Other_IKK_IKBKE_ST	O00571	DDX3X	Q14164	IKBKE	S610	S610Y	610	Missense	central	0	yes	72.289	0.000	EPSD	COSMIC	71.554	Loss
Other_IKK_IKBKE_ST	O00571	DDX3X	Q14164	IKBKE	S610	S611Y	611	Missense	proximal	1	no	72.289	64.859	EPSD	COSMIC	71.554	Loss
Other_IKK_IKBKE_ST	O00571	DDX3X	Q14164	IKBKE	S610	R617K	617	Missense	distal	7	no	72.289	73.288	EPSD	COSMIC	71.554	Up-regulation
Other_IKK_IKBKE_ST	O00571	DDX3X	Q14164	IKBKE	S610	R617I	617	Missense	distal	7	no	72.289	74.792	EPSD	COSMIC	71.554	Up-regulation
Other_IKK_IKBKE_ST	O00571	DDX3X	Q14164	IKBKE	S610	R617T	617	Missense	distal	7	no	72.289	72.603	EPSD	COSMIC	71.554	Up-regulation
Other_IKK_IKBKE_ST	O00571	DDX3X	Q14164	IKBKE	S610	S605G	605	Missense	distal	-5	no	72.289	73.452	EPSD	COSMIC	71.554	Up-regulation
Other_IKK_IKBKE_ST	O00571	DDX3X	Q14164	IKBKE	S610	G607R	607	Missense	distal	-3	no	72.289	70.903	EPSD	COSMIC	71.554	Loss
Other_IKK_IKBKE_ST	O00571	DDX3X	Q14164	IKBKE	S610	S612G	612	Missense	proximal	2	no	72.289	69.689	EPSD	COSMIC	71.554	Loss
Other_IKK_IKBKE_ST	O00571	DDX3X	Q14164	IKBKE	S615	S609Y	609	Missense	distal	-6	no	70.184	72.158	EPSD	COSMIC	71.554	Gain
Other_IKK_IKBKE_ST	O00571	DDX3X	Q14164	IKBKE	S615	S610Y	610	Missense	distal	-5	no	70.184	72.039	EPSD	COSMIC	71.554	Gain
Other_IKK_IKBKE_ST	O00571	DDX3X	Q14164	IKBKE	S615	R622C	622	Missense	distal	7	no	70.184	71.801	EPSD	COSMIC	71.554	Gain
Other_IKK_IKBKE_ST	O00571	DDX3X	Q14164	IKBKE	S615	R617T	617	Missense	proximal	2	no	70.184	71.597	EPSD	COSMIC	71.554	Gain
Other_IKK_IKBKE_ST	O00571	DDX3X	Q14164	IKBKE	S615	S612G	612	Missense	distal	-3	no	70.184	72.291	EPSD	COSMIC	71.554	Gain
Other_IKK_IKBKE_ST	O00571	DDX3X	Q14164	IKBKE	S619	G625V	625	Missense	distal	6	no	80.761	77.721	EPSD	COSMIC	71.554	Down-regulation
Other_IKK_IKBKE_ST	O00571	DDX3X	Q14164	IKBKE	S619	G624R	624	Missense	distal	5	no	80.761	82.338	EPSD	COSMIC	71.554	Up-regulation
Other_IKK_IKBKE_ST	O00571	DDX3X	Q14164	IKBKE	S619	G626V	626	Missense	distal	7	no	80.761	79.989	EPSD	COSMIC	71.554	Down-regulation
Other_IKK_IKBKE_ST	O00571	DDX3X	Q14164	IKBKE	S619	G624D	624	Missense	distal	5	no	80.761	81.469	EPSD	COSMIC;CCLE	71.554	Up-regulation
Other_IKK_IKBKE_ST	O00571	DDX3X	Q14164	IKBKE	S619	R622C	622	Missense	distal	3	no	80.761	75.921	EPSD	COSMIC	71.554	Down-regulation
Other_IKK_IKBKE_ST	O00571	DDX3X	Q14164	IKBKE	S619	R617K	617	Missense	proximal	-2	no	80.761	90.974	EPSD	COSMIC	71.554	Up-regulation
Other_IKK_IKBKE_ST	O00571	DDX3X	Q14164	IKBKE	S619	R617I	617	Missense	proximal	-2	no	80.761	89.053	EPSD	COSMIC	71.554	Up-regulation
Other_IKK_IKBKE_ST	O00571	DDX3X	Q14164	IKBKE	S619	R617T	617	Missense	proximal	-2	no	80.761	91.451	EPSD	COSMIC	71.554	Up-regulation
Other_IKK_IKBKE_ST	O00571	DDX3X	Q14164	IKBKE	S619	S612G	612	Missense	distal	-7	no	80.761	81.238	EPSD	COSMIC	71.554	Up-regulation
Other_IKK_IKBKE_ST	O00571	DDX3X	Q14164	IKBKE	S620	G625V	625	Missense	distal	5	no	73.395	73.181	EPSD	COSMIC	71.554	Down-regulation
Other_IKK_IKBKE_ST	O00571	DDX3X	Q14164	IKBKE	S620	G624R	624	Missense	distal	4	no	73.395	69.755	EPSD	COSMIC	71.554	Loss
Other_IKK_IKBKE_ST	O00571	DDX3X	Q14164	IKBKE	S620	G626V	626	Missense	distal	6	no	73.395	70.354	EPSD	COSMIC	71.554	Loss
Other_IKK_IKBKE_ST	O00571	DDX3X	Q14164	IKBKE	S620	G624D	624	Missense	distal	4	no	73.395	66.565	EPSD	COSMIC;CCLE	71.554	Loss
Other_IKK_IKBKE_ST	O00571	DDX3X	Q14164	IKBKE	S620	R622C	622	Missense	proximal	2	no	73.395	72.807	EPSD	COSMIC	71.554	Down-regulation
Other_IKK_IKBKE_ST	O00571	DDX3X	Q14164	IKBKE	S620	R617K	617	Missense	distal	-3	no	73.395	72.147	EPSD	COSMIC	71.554	Down-regulation
Other_IKK_IKBKE_ST	O00571	DDX3X	Q14164	IKBKE	S620	R617I	617	Missense	distal	-3	no	73.395	70.219	EPSD	COSMIC	71.554	Loss
Other_IKK_IKBKE_ST	O00571	DDX3X	Q14164	IKBKE	S620	R617T	617	Missense	distal	-3	no	73.395	74.021	EPSD	COSMIC	71.554	Up-regulation
Other_IKK_IKBKE_ST	O00571	DDX3X	Q14164	IKBKE	S630	G625V	625	Missense	distal	-5	no	79.620	82.444	EPSD	COSMIC	71.554	Up-regulation
Other_IKK_IKBKE_ST	O00571	DDX3X	Q14164	IKBKE	S630	G633S	633	Missense	distal	3	no	79.620	79.052	EPSD	COSMIC	71.554	Down-regulation
Other_IKK_IKBKE_ST	O00571	DDX3X	Q14164	IKBKE	S630	G624R	624	Missense	distal	-6	no	79.620	77.535	EPSD	COSMIC	71.554	Down-regulation
Other_IKK_IKBKE_ST	O00571	DDX3X	Q14164	IKBKE	S630	G626V	626	Missense	distal	-4	no	79.620	79.929	EPSD	COSMIC	71.554	Up-regulation
Other_IKK_IKBKE_ST	O00571	DDX3X	Q14164	IKBKE	S630	G635E	635	Missense	distal	5	no	79.620	80.567	EPSD	COSMIC	71.554	Up-regulation
Other_IKK_IKBKE_ST	O00571	DDX3X	Q14164	IKBKE	S630	R632T	632	Missense	proximal	2	no	79.620	81.033	EPSD	COSMIC;CCLE	71.554	Up-regulation
Other_IKK_IKBKE_ST	O00571	DDX3X	Q14164	IKBKE	S630	H628Y	628	Missense	proximal	-2	no	79.620	64.318	EPSD	COSMIC	71.554	Loss
Other_IKK_IKBKE_ST	O00571	DDX3X	Q14164	IKBKE	S630	G635S	635	Missense	distal	5	no	79.620	80.199	EPSD	COSMIC	71.554	Up-regulation
Other_IKK_IKBKE_ST	O00571	DDX3X	Q14164	IKBKE	S630	G624D	624	Missense	distal	-6	no	79.620	80.356	EPSD	COSMIC;CCLE	71.554	Up-regulation
Other_IKK_IKBKE_ST	O00571	DDX3X	Q14164	IKBKE	S630	G633E	633	Missense	distal	3	no	79.620	81.460	EPSD	COSMIC	71.554	Up-regulation
Other_IKK_IKBKE_ST	O00571	DDX3X	Q14164	IKBKE	S630	S630G	630	Missense	central	0	yes	79.620	0.000	EPSD	COSMIC	71.554	Loss
Other_IKK_IKBKE_ST	O00571	DDX3X	Q14164	IKBKE	S631	G625V	625	Missense	distal	-6	no	78.417	78.669	EPSD	COSMIC	71.554	Up-regulation
Other_IKK_IKBKE_ST	O00571	DDX3X	Q14164	IKBKE	S631	G633S	633	Missense	proximal	2	no	78.417	81.017	EPSD	COSMIC	71.554	Up-regulation
Other_IKK_IKBKE_ST	O00571	DDX3X	Q14164	IKBKE	S631	G638R	638	Missense	distal	7	no	78.417	76.896	EPSD	COSMIC	71.554	Down-regulation
Other_IKK_IKBKE_ST	O00571	DDX3X	Q14164	IKBKE	S631	G624R	624	Missense	distal	-7	no	78.417	76.990	EPSD	COSMIC	71.554	Down-regulation
Other_IKK_IKBKE_ST	O00571	DDX3X	Q14164	IKBKE	S631	G626V	626	Missense	distal	-5	no	78.417	81.241	EPSD	COSMIC	71.554	Up-regulation
Other_IKK_IKBKE_ST	O00571	DDX3X	Q14164	IKBKE	S631	G635E	635	Missense	distal	4	no	78.417	74.899	EPSD	COSMIC	71.554	Down-regulation
Other_IKK_IKBKE_ST	O00571	DDX3X	Q14164	IKBKE	S631	R632T	632	Missense	proximal	1	no	78.417	77.424	EPSD	COSMIC;CCLE	71.554	Down-regulation
Other_IKK_IKBKE_ST	O00571	DDX3X	Q14164	IKBKE	S631	H628Y	628	Missense	distal	-3	no	78.417	76.265	EPSD	COSMIC	71.554	Down-regulation
Other_IKK_IKBKE_ST	O00571	DDX3X	Q14164	IKBKE	S631	G635S	635	Missense	distal	4	no	78.417	86.063	EPSD	COSMIC	71.554	Up-regulation
Other_IKK_IKBKE_ST	O00571	DDX3X	Q14164	IKBKE	S631	G624D	624	Missense	distal	-7	no	78.417	77.345	EPSD	COSMIC;CCLE	71.554	Down-regulation
Other_IKK_IKBKE_ST	O00571	DDX3X	Q14164	IKBKE	S631	G633E	633	Missense	proximal	2	no	78.417	80.119	EPSD	COSMIC	71.554	Up-regulation
Other_IKK_IKBKE_ST	O00571	DDX3X	Q14164	IKBKE	S631	S630G	630	Missense	proximal	-1	no	78.417	75.279	EPSD	COSMIC	71.554	Down-regulation
Other_IKK_IKBKE_ST	Q04206	RELA	Q14164	IKBKE	S45	E39Q	39	Missense	distal	-6	no	73.237	72.689	EPSD	COSMIC	71.554	Down-regulation
Other_IKK_IKBKE_ST	Q04206	RELA	Q14164	IKBKE	T254	R253L	253	Missense	proximal	-1	no	76.906	71.143	EPSD	COSMIC	71.554	Loss
Other_IKK_IKBKE_ST	Q04206	RELA	Q14164	IKBKE	T254	I250V	250	Missense	distal	-4	no	76.906	82.416	EPSD	COSMIC	71.554	Up-regulation
Other_IKK_IKBKE_ST	Q04206	RELA	Q14164	IKBKE	T254	P256H	256	Missense	proximal	2	no	76.906	74.942	EPSD	COSMIC	71.554	Down-regulation
Other_IKK_IKBKE_ST	Q04206	RELA	Q14164	IKBKE	S311	M313I	313	Missense	proximal	2	no	80.995	72.732	EPSD	COSMIC	71.554	Down-regulation
Other_IKK_IKBKE_ST	Q04206	RELA	Q14164	IKBKE	S311	K314N	314	Missense	distal	3	no	80.995	83.089	EPSD	COSMIC	71.554	Up-regulation
Other_IKK_IKBKE_ST	Q04206	RELA	Q14164	IKBKE	S311	T305A	305	Missense	distal	-6	no	80.995	82.421	EPSD	COSMIC	71.554	Up-regulation
Other_IKK_IKBKE_ST	Q04206	RELA	Q14164	IKBKE	S536	F534L	534	Missense	proximal	-2	no	85.327	83.351	PhosphoSitePlus;EPSD	COSMIC	71.554	Down-regulation
Other_IKK_IKBKE_ST	Q14164	IKBKE	Q14164	IKBKE	S172	G175R	175	Missense	distal	3	no	100.814	101.897	EPSD	COSMIC	71.554	Up-regulation
Other_IKK_IKBKE_ST	Q14164	IKBKE	Q14164	IKBKE	S172	E168D	168	Missense	distal	-4	no	100.814	98.959	EPSD	COSMIC	71.554	Down-regulation
Other_IKK_IKBKE_ST	Q14164	IKBKE	Q14164	IKBKE	S172	Y179F	179	Missense	distal	7	no	100.814	101.194	EPSD	COSMIC	71.554	Up-regulation
Other_IKK_IKBKE_ST	Q14164	IKBKE	Q14164	IKBKE	S172	V171I	171	Missense	proximal	-1	no	100.814	89.827	EPSD	COSMIC	71.554	Down-regulation
Other_IKK_IKBKE_ST	Q14164	IKBKE	Q14164	IKBKE	S172	E177Q	177	Missense	distal	5	no	100.814	100.895	EPSD	COSMIC	71.554	Up-regulation
Other_IKK_IKBKE_ST	Q14164	IKBKE	Q14164	IKBKE	T474	V480M	480	Missense	distal	6	no	75.814	79.842	EPSD	COSMIC	71.554	Up-regulation
Other_IKK_IKBKE_ST	Q14164	IKBKE	Q14164	IKBKE	S479	V480M	480	Missense	proximal	1	no	90.469	93.972	EPSD	COSMIC	71.554	Up-regulation
Other_IKK_IKBKE_ST	Q14164	IKBKE	Q14164	IKBKE	S479	G482V	482	Missense	distal	3	no	90.469	90.328	EPSD	COSMIC	71.554	Down-regulation
Other_IKK_IKBKE_ST	Q14164	IKBKE	Q14164	IKBKE	S479	E485A	485	Missense	distal	6	no	90.469	92.750	EPSD	COSMIC	71.554	Up-regulation
Other_IKK_IKBKE_ST	Q14164	IKBKE	Q14164	IKBKE	S519	T514M	514	Missense	distal	-5	no	80.018	70.080	EPSD	COSMIC	71.554	Loss
Other_IKK_IKBKE_ST	Q14164	IKBKE	Q14164	IKBKE	S519	T516I	516	Missense	distal	-3	no	80.018	76.215	EPSD	COSMIC	71.554	Down-regulation
Other_IKK_IKBKE_ST	Q14164	IKBKE	Q14164	IKBKE	S519	R525P	525	Missense	distal	6	no	80.018	81.177	EPSD	COSMIC	71.554	Up-regulation
Other_IKK_IKBKE_ST	Q14164	IKBKE	Q14164	IKBKE	S519	T514A	514	Missense	distal	-5	no	80.018	69.660	EPSD	COSMIC	71.554	Loss
Other_IKK_IKBKE_ST	Q14164	IKBKE	Q14164	IKBKE	S519	R525K	525	Missense	distal	6	no	80.018	83.120	EPSD	COSMIC	71.554	Up-regulation
Other_IKK_IKBKE_ST	Q14164	IKBKE	Q14164	IKBKE	S522	T516I	516	Missense	distal	-6	no	90.537	94.071	EPSD	COSMIC	71.554	Up-regulation
Other_IKK_IKBKE_ST	Q14164	IKBKE	Q14164	IKBKE	S522	R525P	525	Missense	distal	3	no	90.537	88.918	EPSD	COSMIC	71.554	Down-regulation
Other_IKK_IKBKE_ST	Q14164	IKBKE	Q14164	IKBKE	S522	V528M	528	Missense	distal	6	no	90.537	94.565	EPSD	COSMIC	71.554	Up-regulation
Other_IKK_IKBKE_ST	Q14164	IKBKE	Q14164	IKBKE	S522	R525K	525	Missense	distal	3	no	90.537	89.005	EPSD	COSMIC	71.554	Down-regulation
Other_IKK_IKBKE_ST	O43524	FOXO3	Q14164	IKBKE	S26	R29L	29	Missense	distal	3	no	72.410	70.104	EPSD	COSMIC	71.554	Loss
Other_IKK_IKBKE_ST	O43524	FOXO3	Q14164	IKBKE	S257	S253F	253	Missense	distal	-4	no	76.074	74.717	EPSD	COSMIC	71.554	Down-regulation
Other_IKK_IKBKE_ST	O43524	FOXO3	Q14164	IKBKE	T313	S318C	318	Missense	distal	5	no	78.900	75.691	EPSD	COSMIC	71.554	Down-regulation
Other_IKK_IKBKE_ST	O43524	FOXO3	Q14164	IKBKE	S325	R323H	323	Missense	proximal	-2	no	65.302	82.404	EPSD	COSMIC	71.554	Gain
Other_IKK_IKBKE_ST	O43524	FOXO3	Q14164	IKBKE	S355	P361L	361	Missense	distal	6	no	72.533	69.466	EPSD	COSMIC;GDSC;CCLE	71.554	Loss
Other_IKK_IKBKE_ST	O43524	FOXO3	Q14164	IKBKE	S425	G424V	424	Missense	proximal	-1	no	79.149	86.062	EPSD	COSMIC	71.554	Up-regulation
Other_IKK_IKBKE_ST	O43524	FOXO3	Q14164	IKBKE	S429	G424V	424	Missense	distal	-5	no	74.376	77.201	EPSD	COSMIC	71.554	Up-regulation
Other_IKK_IKBKE_ST	P49840	GSK3A	Q14164	IKBKE	S129	S129L	129	Missense	central	0	yes	80.784	0.000	EPSD	COSMIC	71.554	Loss
Other_IKK_IKBKE_ST	P49840	GSK3A	Q14164	IKBKE	S129	F130V	130	Missense	proximal	1	no	80.784	70.103	EPSD	COSMIC;GDSC;CCLE	71.554	Loss
Other_IKK_IKBKE_ST	P49840	GSK3A	Q14164	IKBKE	S129	G128S	128	Missense	proximal	-1	no	80.784	83.922	EPSD	COSMIC	71.554	Up-regulation
Other_IKK_IKBKE_ST	P49840	GSK3A	Q14164	IKBKE	S129	I122M	122	Missense	distal	-7	no	80.784	78.974	EPSD	COSMIC	71.554	Down-regulation
Other_IKK_IKBKE_ST	P49840	GSK3A	Q14164	IKBKE	S129	G131V	131	Missense	proximal	2	no	80.784	83.627	EPSD	COSMIC	71.554	Up-regulation
Other_IKK_IKBKE_ST	P49840	GSK3A	Q14164	IKBKE	S401	C398Y	398	Missense	distal	-3	no	78.685	76.946	EPSD	COSMIC	71.554	Down-regulation
Other_IKK_IKBKE_ST	P49840	GSK3A	Q14164	IKBKE	S401	H400R	400	Missense	proximal	-1	no	78.685	85.441	EPSD	COSMIC	71.554	Up-regulation
Other_IKK_IKBKE_ST	P49840	GSK3A	Q14164	IKBKE	S401	H400L	400	Missense	proximal	-1	no	78.685	79.678	EPSD	COSMIC	71.554	Up-regulation
Other_IKK_IKBKE_ST	P49840	GSK3A	Q14164	IKBKE	S401	D404Y	404	Missense	distal	3	no	78.685	77.317	EPSD	COSMIC	71.554	Down-regulation
Other_IKK_IKBKE_ST	P49840	GSK3A	Q14164	IKBKE	S401	A399V	399	Missense	proximal	-2	no	78.685	81.739	EPSD	COSMIC	71.554	Up-regulation
Other_IKK_IKBKE_ST	Q9UNN5	FAF1	Q14164	IKBKE	S314	E308Q	308	Missense	distal	-6	no	77.414	76.866	EPSD	COSMIC	71.554	Down-regulation
Other_IKK_IKBKE_ST	Q9UNN5	FAF1	Q14164	IKBKE	S314	L317F	317	Missense	distal	3	no	77.414	79.181	EPSD	COSMIC	71.554	Up-regulation
Other_IKK_IKBKE_ST	Q9UNN5	FAF1	Q14164	IKBKE	S314	S314L	314	Missense	central	0	yes	77.414	0.000	EPSD	COSMIC	71.554	Loss
CMGC_MAPK_p38_MAPK12_ST	P15172	MYOD1	P53778	MAPK12	S201	A199E	199	Missense	proximal	-2	no	132.509	123.201	PhosphoSitePlus;EPSD	COSMIC	112.929	Down-regulation
CMGC_MAPK_p38_MAPK12_ST	P15172	MYOD1	P53778	MAPK12	S201	S200Y	200	Missense	proximal	-1	no	132.509	131.781	PhosphoSitePlus;EPSD	COSMIC	112.929	Down-regulation
CMGC_MAPK_p38_MAPK12_ST	P15172	MYOD1	P53778	MAPK12	S201	D196N	196	Missense	distal	-5	no	132.509	132.462	PhosphoSitePlus;EPSD	COSMIC	112.929	Down-regulation
CMGC_MAPK_p38_MAPK12_ST	P15172	MYOD1	P53778	MAPK12	S201	G195S	195	Missense	distal	-6	no	132.509	131.187	PhosphoSitePlus;EPSD	COSMIC	112.929	Down-regulation
CMGC_MAPK_p38_MAPK12_ST	P15172	MYOD1	P53778	MAPK12	S201	R203C	203	Missense	proximal	2	no	132.509	131.994	PhosphoSitePlus;EPSD	COSMIC	112.929	Down-regulation
CMGC_MAPK_p38_MAPK12_ST	P15172	MYOD1	P53778	MAPK12	S201	C206F	206	Missense	distal	5	no	132.509	132.335	PhosphoSitePlus;EPSD	COSMIC	112.929	Down-regulation
CMGC_MAPK_p38_MAPK12_ST	Q12959	DLG1	P53778	MAPK12	T115	I121V	121	Missense	distal	6	no	119.323	118.485	EPSD	COSMIC	112.929	Down-regulation
CMGC_MAPK_p38_MAPK12_ST	Q12959	DLG1	P53778	MAPK12	T115	D114N	114	Missense	proximal	-1	no	119.323	118.315	EPSD	COSMIC	112.929	Down-regulation
CMGC_MAPK_p38_MAPK12_ST	Q12959	DLG1	P53778	MAPK12	S122	I121V	121	Missense	proximal	-1	no	120.748	118.866	PhosphoSitePlus;EPSD	COSMIC	112.929	Down-regulation
CMGC_MAPK_p38_MAPK12_ST	Q12959	DLG1	P53778	MAPK12	S158	I160V	160	Missense	proximal	2	no	133.815	132.538	EPSD;PhosphoSitePlus	COSMIC;CCLE	112.929	Down-regulation
CMGC_MAPK_p38_MAPK12_ST	Q12959	DLG1	P53778	MAPK12	T209	T209A	209	Missense	central	0	yes	136.800	0.000	EPSD;PhosphoSitePlus	COSMIC	112.929	Loss
CMGC_MAPK_p38_MAPK12_ST	Q12959	DLG1	P53778	MAPK12	S232	F236V	236	Missense	distal	4	no	113.175	113.906	EPSD	COSMIC;CCLE	112.929	Up-regulation
CMGC_MAPK_p38_MAPK12_ST	Q12959	DLG1	P53778	MAPK12	S232	A239T	239	Missense	distal	7	no	113.175	112.292	EPSD	COSMIC	112.929	Loss
CMGC_MAPK_p38_MAPK12_ST	Q12959	DLG1	P53778	MAPK12	S232	S232L	232	Missense	central	0	yes	113.175	0.000	EPSD	COSMIC	112.929	Loss
CMGC_MAPK_p38_MAPK12_ST	Q12959	DLG1	P53778	MAPK12	S432	Q439L	439	Missense	distal	7	no	137.071	137.500	EPSD	COSMIC	112.929	Up-regulation
CMGC_MAPK_p38_MAPK12_ST	Q12959	DLG1	P53778	MAPK12	T440	Q439L	439	Missense	proximal	-1	no	125.159	125.341	EPSD	COSMIC	112.929	Up-regulation
CMGC_MAPK_p38_MAPK12_ST	Q12959	DLG1	P53778	MAPK12	S443	Q439L	439	Missense	distal	-4	no	145.026	141.818	EPSD;PhosphoSitePlus	COSMIC	112.929	Down-regulation
CMGC_MAPK_p38_MAPK12_ST	Q12959	DLG1	P53778	MAPK12	S448	A453V	453	Missense	distal	5	no	115.530	114.726	EPSD	COSMIC	112.929	Down-regulation
CMGC_MAPK_p38_MAPK12_ST	Q12959	DLG1	P53778	MAPK12	S448	V454I	454	Missense	distal	6	no	115.530	116.368	EPSD	COSMIC;GDSC;CCLE	112.929	Up-regulation
CMGC_MAPK_p38_MAPK12_ST	Q12959	DLG1	P53778	MAPK12	S448	L455I	455	Missense	distal	7	no	115.530	117.122	EPSD	COSMIC	112.929	Up-regulation
CMGC_MAPK_p38_MAPK12_ST	Q12959	DLG1	P53778	MAPK12	S583	Q580E	580	Missense	distal	-3	no	118.139	117.826	EPSD	COSMIC	112.929	Down-regulation
CMGC_MAPK_p38_MAPK12_ST	Q12959	DLG1	P53778	MAPK12	S583	R577Q	577	Missense	distal	-6	no	118.139	118.648	EPSD	COSMIC	112.929	Up-regulation
CMGC_MAPK_p38_MAPK12_ST	Q12959	DLG1	P53778	MAPK12	S583	Y585C	585	Missense	proximal	2	no	118.139	117.103	EPSD	COSMIC	112.929	Down-regulation
CMGC_MAPK_p38_MAPK12_ST	Q12959	DLG1	P53778	MAPK12	S583	R587G	587	Missense	distal	4	no	118.139	119.177	EPSD	COSMIC	112.929	Up-regulation
CMGC_MAPK_p38_MAPK12_ST	Q12959	DLG1	P53778	MAPK12	S583	V586D	586	Missense	distal	3	no	118.139	119.680	EPSD	COSMIC	112.929	Up-regulation
CMGC_MAPK_p38_MAPK12_ST	Q12959	DLG1	P53778	MAPK12	S583	L576F	576	Missense	distal	-7	no	118.139	118.365	EPSD	COSMIC	112.929	Up-regulation
CMGC_MAPK_p38_MAPK12_ST	Q12959	DLG1	P53778	MAPK12	S583	R587K	587	Missense	distal	4	no	118.139	118.657	EPSD	COSMIC	112.929	Up-regulation
CMGC_MAPK_p38_MAPK12_ST	Q12959	DLG1	P53778	MAPK12	S583	L589I	589	Missense	distal	6	no	118.139	118.741	EPSD	COSMIC	112.929	Up-regulation
CMGC_MAPK_p38_MAPK12_ST	Q12959	DLG1	P53778	MAPK12	T630	T630K	630	Missense	central	0	yes	118.552	0.000	EPSD	COSMIC	112.929	Loss
CMGC_MAPK_p38_MAPK12_ST	Q12959	DLG1	P53778	MAPK12	T630	T630I	630	Missense	central	0	yes	118.552	0.000	EPSD	COSMIC	112.929	Loss
CMGC_MAPK_p38_MAPK12_ST	Q12959	DLG1	P53778	MAPK12	T630	G633C	633	Missense	distal	3	no	118.552	118.023	EPSD	COSMIC	112.929	Down-regulation
CMGC_MAPK_p38_MAPK12_ST	Q12959	DLG1	P53778	MAPK12	T630	G633V	633	Missense	distal	3	no	118.552	117.881	EPSD	COSMIC	112.929	Down-regulation
CMGC_MAPK_p38_MAPK12_ST	Q12959	DLG1	P53778	MAPK12	T630	D636N	636	Missense	distal	6	no	118.552	118.167	EPSD	COSMIC	112.929	Down-regulation
CMGC_MAPK_p38_MAPK12_ST	Q00613	HSF1	P53778	MAPK12	S230	R227Q	227	Missense	distal	-3	no	113.821	113.836	EPSD	COSMIC;GDSC	112.929	Up-regulation
CMGC_MAPK_p38_MAPK12_ST	Q00613	HSF1	P53778	MAPK12	S230	G236S	236	Missense	distal	6	no	113.821	113.852	EPSD	COSMIC;CCLE	112.929	Up-regulation
CMGC_MAPK_p38_MAPK12_ST	Q00613	HSF1	P53778	MAPK12	S230	S237L	237	Missense	distal	7	no	113.821	112.261	EPSD	COSMIC	112.929	Loss
CMGC_MAPK_p38_MAPK12_ST	Q00613	HSF1	P53778	MAPK12	S237	G236S	236	Missense	proximal	-1	no	117.218	117.583	EPSD	COSMIC;CCLE	112.929	Up-regulation
CMGC_MAPK_p38_MAPK12_ST	Q00613	HSF1	P53778	MAPK12	S237	S237L	237	Missense	central	0	yes	117.218	0.000	EPSD	COSMIC	112.929	Loss
CMGC_MAPK_p38_MAPK12_ST	Q00613	HSF1	P53778	MAPK12	S237	P239H	239	Missense	proximal	2	no	117.218	116.665	EPSD	COSMIC	112.929	Down-regulation
CMGC_MAPK_p38_MAPK12_ST	Q00613	HSF1	P53778	MAPK12	S237	S244F	244	Missense	distal	7	no	117.218	115.640	EPSD	COSMIC	112.929	Down-regulation
CMGC_MAPK_p38_MAPK12_ST	Q00613	HSF1	P53778	MAPK12	S244	S237L	237	Missense	distal	-7	no	127.884	130.192	EPSD	COSMIC	112.929	Up-regulation
CMGC_MAPK_p38_MAPK12_ST	Q00613	HSF1	P53778	MAPK12	S244	P239H	239	Missense	distal	-5	no	127.884	127.724	EPSD	COSMIC	112.929	Down-regulation
CMGC_MAPK_p38_MAPK12_ST	Q00613	HSF1	P53778	MAPK12	S244	S244F	244	Missense	central	0	yes	127.884	0.000	EPSD	COSMIC	112.929	Loss
CMGC_MAPK_p38_MAPK12_ST	Q00613	HSF1	P53778	MAPK12	S251	S244F	244	Missense	distal	-7	no	114.466	117.000	EPSD	COSMIC	112.929	Up-regulation
CMGC_MAPK_p38_MAPK12_ST	Q00613	HSF1	P53778	MAPK12	S275	S279F	279	Missense	distal	4	no	135.072	133.462	EPSD	COSMIC	112.929	Down-regulation
CMGC_MAPK_p38_MAPK12_ST	Q00613	HSF1	P53778	MAPK12	S275	P280L	280	Missense	distal	5	no	135.072	134.376	EPSD	COSMIC	112.929	Down-regulation
CMGC_MAPK_p38_MAPK12_ST	Q00613	HSF1	P53778	MAPK12	S275	I268V	268	Missense	distal	-7	no	135.072	137.179	EPSD	COSMIC	112.929	Up-regulation
CMGC_MAPK_p38_MAPK12_ST	Q00613	HSF1	P53778	MAPK12	S275	G281S	281	Missense	distal	6	no	135.072	135.103	EPSD	COSMIC	112.929	Up-regulation
CMGC_MAPK_p38_MAPK12_ST	Q00613	HSF1	P53778	MAPK12	S279	S279F	279	Missense	central	0	yes	130.024	0.000	EPSD	COSMIC	112.929	Loss
CMGC_MAPK_p38_MAPK12_ST	Q00613	HSF1	P53778	MAPK12	S279	P280L	280	Missense	proximal	1	no	130.024	113.279	EPSD	COSMIC	112.929	Down-regulation
CMGC_MAPK_p38_MAPK12_ST	Q00613	HSF1	P53778	MAPK12	S279	G281S	281	Missense	proximal	2	no	130.024	130.744	EPSD	COSMIC	112.929	Up-regulation
CMGC_MAPK_p38_MAPK12_ST	Q00613	HSF1	P53778	MAPK12	S279	S283N	283	Missense	distal	4	no	130.024	129.701	EPSD	COSMIC	112.929	Down-regulation
CMGC_MAPK_p38_MAPK12_ST	Q00613	HSF1	P53778	MAPK12	S292	R287K	287	Missense	distal	-5	no	125.557	125.726	EPSD	COSMIC	112.929	Up-regulation
CMGC_MAPK_p38_MAPK12_ST	Q00613	HSF1	P53778	MAPK12	S303	S303G	303	Missense	central	0	yes	135.892	0.000	EPSD;PhosphoSitePlus	COSMIC	112.929	Loss
CMGC_MAPK_p38_MAPK12_ST	Q00613	HSF1	P53778	MAPK12	S303	P304L	304	Missense	proximal	1	no	135.892	119.147	EPSD;PhosphoSitePlus	COSMIC;GDSC	112.929	Down-regulation
CMGC_MAPK_p38_MAPK12_ST	Q00613	HSF1	P53778	MAPK12	S303	R309G	309	Missense	distal	6	no	135.892	136.722	EPSD;PhosphoSitePlus	COSMIC	112.929	Up-regulation
CMGC_MAPK_p38_MAPK12_ST	Q00613	HSF1	P53778	MAPK12	S307	S303G	303	Missense	distal	-4	no	139.350	138.654	PhosphoSitePlus;EPSD	COSMIC	112.929	Down-regulation
CMGC_MAPK_p38_MAPK12_ST	Q00613	HSF1	P53778	MAPK12	S307	P304L	304	Missense	distal	-3	no	139.350	138.889	PhosphoSitePlus;EPSD	COSMIC;GDSC	112.929	Down-regulation
CMGC_MAPK_p38_MAPK12_ST	Q00613	HSF1	P53778	MAPK12	S307	R309G	309	Missense	proximal	2	no	139.350	139.321	PhosphoSitePlus;EPSD	COSMIC	112.929	Down-regulation
CMGC_MAPK_p38_MAPK12_ST	Q00613	HSF1	P53778	MAPK12	S314	R309G	309	Missense	distal	-5	no	116.105	116.302	EPSD	COSMIC	112.929	Up-regulation
CMGC_MAPK_p38_MAPK12_ST	Q00613	HSF1	P53778	MAPK12	S314	P318T	318	Missense	distal	4	no	116.105	115.858	EPSD	COSMIC	112.929	Down-regulation
CMGC_MAPK_p38_MAPK12_ST	Q00613	HSF1	P53778	MAPK12	S326	L330V	330	Missense	distal	4	no	132.568	132.498	EPSD;PhosphoSitePlus	COSMIC	112.929	Down-regulation
CMGC_MAPK_p38_MAPK12_ST	Q00613	HSF1	P53778	MAPK12	S326	P327Q	327	Missense	proximal	1	no	132.568	-65.440	EPSD;PhosphoSitePlus	COSMIC	112.929	Loss
CMGC_MAPK_p38_MAPK12_ST	Q00613	HSF1	P53778	MAPK12	S363	S363P	363	Missense	central	0	yes	129.909	0.000	EPSD	COSMIC	112.929	Loss
CMGC_MAPK_p38_MAPK12_ST	Q00613	HSF1	P53778	MAPK12	S363	P365Q	365	Missense	proximal	2	no	129.909	129.309	EPSD	COSMIC	112.929	Down-regulation
CMGC_MAPK_p38_MAPK12_ST	Q00613	HSF1	P53778	MAPK12	S363	D356N	356	Missense	distal	-7	no	129.909	130.520	EPSD	COSMIC	112.929	Up-regulation
CMGC_MAPK_p38_MAPK12_ST	Q00613	HSF1	P53778	MAPK12	S363	P365T	365	Missense	proximal	2	no	129.909	129.895	EPSD	COSMIC	112.929	Down-regulation
CMGC_MAPK_p38_MAPK12_ST	Q00613	HSF1	P53778	MAPK12	S363	E358K	358	Missense	distal	-5	no	129.909	130.139	EPSD	COSMIC	112.929	Up-regulation
CMGC_MAPK_p38_MAPK12_ST	Q00613	HSF1	P53778	MAPK12	S363	P365L	365	Missense	proximal	2	no	129.909	129.012	EPSD	COSMIC	112.929	Down-regulation
CMGC_MAPK_p38_MAPK12_ST	Q00613	HSF1	P53778	MAPK12	T369	S363P	363	Missense	distal	-6	no	118.876	118.906	EPSD	COSMIC	112.929	Up-regulation
CMGC_MAPK_p38_MAPK12_ST	Q00613	HSF1	P53778	MAPK12	T369	P365Q	365	Missense	distal	-4	no	118.876	120.284	EPSD	COSMIC	112.929	Up-regulation
CMGC_MAPK_p38_MAPK12_ST	Q00613	HSF1	P53778	MAPK12	T369	P365T	365	Missense	distal	-4	no	118.876	119.468	EPSD	COSMIC	112.929	Up-regulation
CMGC_MAPK_p38_MAPK12_ST	Q00613	HSF1	P53778	MAPK12	T369	L374F	374	Missense	distal	5	no	118.876	117.934	EPSD	COSMIC	112.929	Down-regulation
CMGC_MAPK_p38_MAPK12_ST	Q00613	HSF1	P53778	MAPK12	T369	P365L	365	Missense	distal	-4	no	118.876	117.076	EPSD	COSMIC	112.929	Down-regulation
CMGC_MAPK_p38_MAPK12_ST	Q00613	HSF1	P53778	MAPK12	S419	L417Q	417	Missense	proximal	-2	no	129.769	125.142	EPSD	COSMIC	112.929	Down-regulation
CMGC_MAPK_p38_MAPK12_ST	Q00613	HSF1	P53778	MAPK12	S419	V422M	422	Missense	distal	3	no	129.769	130.310	EPSD	COSMIC	112.929	Up-regulation
CMGC_MAPK_p38_MAPK12_ST	Q00613	HSF1	P53778	MAPK12	S419	S419N	419	Missense	central	0	yes	129.769	0.000	EPSD	COSMIC	112.929	Loss
CMGC_MAPK_p38_MAPK12_ST	Q00613	HSF1	P53778	MAPK12	S444	E447K	447	Missense	distal	3	no	122.921	123.379	EPSD	COSMIC	112.929	Up-regulation
CMGC_MAPK_p38_MAPK12_ST	Q00613	HSF1	P53778	MAPK12	S458	P452H	452	Missense	distal	-6	no	120.860	122.621	EPSD	COSMIC	112.929	Up-regulation
CMGC_MAPK_p38_MAPK12_ST	Q00613	HSF1	P53778	MAPK12	S513	E519K	519	Missense	distal	6	no	113.772	114.391	EPSD	COSMIC	112.929	Up-regulation
CMGC_MAPK_p38_MAPK12_ST	P35222	CTNNB1	P53778	MAPK12	S33	A39G	39	Missense	distal	6	no	120.324	120.431	EPSD	COSMIC	112.929	Up-regulation
CMGC_MAPK_p38_MAPK12_ST	P35222	CTNNB1	P53778	MAPK12	S33	G38A	38	Missense	distal	5	no	120.324	119.969	EPSD	COSMIC	112.929	Down-regulation
CMGC_MAPK_p38_MAPK12_ST	P35222	CTNNB1	P53778	MAPK12	S33	T40I	40	Missense	distal	7	no	120.324	121.007	EPSD	COSMIC	112.929	Up-regulation
CMGC_MAPK_p38_MAPK12_ST	P35222	CTNNB1	P53778	MAPK12	S33	I35T	35	Missense	proximal	2	no	120.324	119.877	EPSD	COSMIC	112.929	Down-regulation
CMGC_MAPK_p38_MAPK12_ST	P35222	CTNNB1	P53778	MAPK12	S33	Q28E	28	Missense	distal	-5	no	120.324	120.308	EPSD	COSMIC	112.929	Down-regulation
CMGC_MAPK_p38_MAPK12_ST	P35222	CTNNB1	P53778	MAPK12	S33	D32E	32	Missense	proximal	-1	no	120.324	117.414	EPSD	COSMIC	112.929	Down-regulation
CMGC_MAPK_p38_MAPK12_ST	P35222	CTNNB1	P53778	MAPK12	S33	H36R	36	Missense	distal	3	no	120.324	120.052	EPSD	COSMIC	112.929	Down-regulation
CMGC_MAPK_p38_MAPK12_ST	P35222	CTNNB1	P53778	MAPK12	S33	T40A	40	Missense	distal	7	no	120.324	121.206	EPSD	COSMIC	112.929	Up-regulation
CMGC_MAPK_p38_MAPK12_ST	P35222	CTNNB1	P53778	MAPK12	S33	G34L	34	Missense	proximal	1	no	120.324	119.957	EPSD	COSMIC	112.929	Down-regulation
CMGC_MAPK_p38_MAPK12_ST	P35222	CTNNB1	P53778	MAPK12	S33	S33L	33	Missense	central	0	yes	120.324	0.000	EPSD	COSMIC;CCLE	112.929	Loss
CMGC_MAPK_p38_MAPK12_ST	P35222	CTNNB1	P53778	MAPK12	S33	S29P	29	Missense	distal	-4	no	120.324	116.248	EPSD	COSMIC	112.929	Down-regulation
CMGC_MAPK_p38_MAPK12_ST	P35222	CTNNB1	P53778	MAPK12	S33	L31P	31	Missense	proximal	-2	no	120.324	125.979	EPSD	COSMIC	112.929	Up-regulation
CMGC_MAPK_p38_MAPK12_ST	P35222	CTNNB1	P53778	MAPK12	S33	S37L	37	Missense	distal	4	no	120.324	119.516	EPSD	COSMIC	112.929	Down-regulation
CMGC_MAPK_p38_MAPK12_ST	P35222	CTNNB1	P53778	MAPK12	S33	A39T	39	Missense	distal	6	no	120.324	119.973	EPSD	COSMIC	112.929	Down-regulation
CMGC_MAPK_p38_MAPK12_ST	P35222	CTNNB1	P53778	MAPK12	S33	Q27H	27	Missense	distal	-6	no	120.324	119.058	EPSD	COSMIC	112.929	Down-regulation
CMGC_MAPK_p38_MAPK12_ST	P35222	CTNNB1	P53778	MAPK12	S33	S33N	33	Missense	central	0	yes	120.324	0.000	EPSD	COSMIC	112.929	Loss
CMGC_MAPK_p38_MAPK12_ST	P35222	CTNNB1	P53778	MAPK12	S33	H36Y	36	Missense	distal	3	no	120.324	120.639	EPSD	COSMIC	112.929	Up-regulation
CMGC_MAPK_p38_MAPK12_ST	P35222	CTNNB1	P53778	MAPK12	S33	S29F	29	Missense	distal	-4	no	120.324	109.185	EPSD	COSMIC	112.929	Loss
CMGC_MAPK_p38_MAPK12_ST	P35222	CTNNB1	P53778	MAPK12	S33	Y30C	30	Missense	distal	-3	no	120.324	119.503	EPSD	COSMIC	112.929	Down-regulation
CMGC_MAPK_p38_MAPK12_ST	P35222	CTNNB1	P53778	MAPK12	S33	S29Y	29	Missense	distal	-4	no	120.324	117.070	EPSD	COSMIC	112.929	Down-regulation
CMGC_MAPK_p38_MAPK12_ST	P35222	CTNNB1	P53778	MAPK12	S33	G38P	38	Missense	distal	5	no	120.324	120.143	EPSD	COSMIC	112.929	Down-regulation
CMGC_MAPK_p38_MAPK12_ST	P35222	CTNNB1	P53778	MAPK12	S33	G38D	38	Missense	distal	5	no	120.324	120.777	EPSD	COSMIC	112.929	Up-regulation
CMGC_MAPK_p38_MAPK12_ST	P35222	CTNNB1	P53778	MAPK12	S33	I35M	35	Missense	proximal	2	no	120.324	119.545	EPSD	COSMIC	112.929	Down-regulation
CMGC_MAPK_p38_MAPK12_ST	P35222	CTNNB1	P53778	MAPK12	S33	T40S	40	Missense	distal	7	no	120.324	120.974	EPSD	COSMIC	112.929	Up-regulation
CMGC_MAPK_p38_MAPK12_ST	P35222	CTNNB1	P53778	MAPK12	S33	S29A	29	Missense	distal	-4	no	120.324	116.284	EPSD	COSMIC	112.929	Down-regulation
CMGC_MAPK_p38_MAPK12_ST	P35222	CTNNB1	P53778	MAPK12	S33	G34A	34	Missense	proximal	1	no	120.324	51.558	EPSD	COSMIC	112.929	Loss
CMGC_MAPK_p38_MAPK12_ST	P35222	CTNNB1	P53778	MAPK12	S33	L31W	31	Missense	proximal	-2	no	120.324	117.827	EPSD	COSMIC	112.929	Down-regulation
CMGC_MAPK_p38_MAPK12_ST	P35222	CTNNB1	P53778	MAPK12	S33	G34I	34	Missense	proximal	1	no	120.324	89.611	EPSD	COSMIC	112.929	Loss
CMGC_MAPK_p38_MAPK12_ST	P35222	CTNNB1	P53778	MAPK12	S33	I35N	35	Missense	proximal	2	no	120.324	120.179	EPSD	COSMIC	112.929	Down-regulation
CMGC_MAPK_p38_MAPK12_ST	P35222	CTNNB1	P53778	MAPK12	S33	D32C	32	Missense	proximal	-1	no	120.324	116.874	EPSD	COSMIC	112.929	Down-regulation
CMGC_MAPK_p38_MAPK12_ST	P35222	CTNNB1	P53778	MAPK12	S33	Y30S	30	Missense	distal	-3	no	120.324	120.468	EPSD	COSMIC	112.929	Up-regulation
CMGC_MAPK_p38_MAPK12_ST	P35222	CTNNB1	P53778	MAPK12	S33	L31M	31	Missense	proximal	-2	no	120.324	118.021	EPSD	COSMIC	112.929	Down-regulation
CMGC_MAPK_p38_MAPK12_ST	P35222	CTNNB1	P53778	MAPK12	S33	A39V	39	Missense	distal	6	no	120.324	119.567	EPSD	COSMIC	112.929	Down-regulation
CMGC_MAPK_p38_MAPK12_ST	P35222	CTNNB1	P53778	MAPK12	S33	L31Q	31	Missense	proximal	-2	no	120.324	115.697	EPSD	COSMIC	112.929	Down-regulation
CMGC_MAPK_p38_MAPK12_ST	P35222	CTNNB1	P53778	MAPK12	S33	G34D	34	Missense	proximal	1	no	120.324	8.114	EPSD	COSMIC	112.929	Loss
CMGC_MAPK_p38_MAPK12_ST	P35222	CTNNB1	P53778	MAPK12	S33	Q26R	26	Missense	distal	-7	no	120.324	120.236	EPSD	COSMIC;GDSC;CCLE	112.929	Down-regulation
CMGC_MAPK_p38_MAPK12_ST	P35222	CTNNB1	P53778	MAPK12	S33	S37T	37	Missense	distal	4	no	120.324	119.816	EPSD	COSMIC	112.929	Down-regulation
CMGC_MAPK_p38_MAPK12_ST	P35222	CTNNB1	P53778	MAPK12	S33	I35K	35	Missense	proximal	2	no	120.324	120.096	EPSD	COSMIC	112.929	Down-regulation
CMGC_MAPK_p38_MAPK12_ST	P35222	CTNNB1	P53778	MAPK12	S33	Q28R	28	Missense	distal	-5	no	120.324	120.369	EPSD	COSMIC	112.929	Up-regulation
CMGC_MAPK_p38_MAPK12_ST	P35222	CTNNB1	P53778	MAPK12	S33	D32F	32	Missense	proximal	-1	no	120.324	116.628	EPSD	COSMIC	112.929	Down-regulation
CMGC_MAPK_p38_MAPK12_ST	P35222	CTNNB1	P53778	MAPK12	S33	G38X	38	Missense	distal	5	no	120.324	119.490	EPSD	COSMIC	112.929	Down-regulation
CMGC_MAPK_p38_MAPK12_ST	P35222	CTNNB1	P53778	MAPK12	S33	D32X	32	Missense	proximal	-1	no	120.324	118.158	EPSD	COSMIC	112.929	Down-regulation
CMGC_MAPK_p38_MAPK12_ST	P35222	CTNNB1	P53778	MAPK12	S33	S33K	33	Missense	central	0	yes	120.324	0.000	EPSD	COSMIC	112.929	Loss
CMGC_MAPK_p38_MAPK12_ST	P35222	CTNNB1	P53778	MAPK12	S33	I35V	35	Missense	proximal	2	no	120.324	119.047	EPSD	COSMIC	112.929	Down-regulation
CMGC_MAPK_p38_MAPK12_ST	P35222	CTNNB1	P53778	MAPK12	S33	S29T	29	Missense	distal	-4	no	120.324	116.840	EPSD	COSMIC	112.929	Down-regulation
CMGC_MAPK_p38_MAPK12_ST	P35222	CTNNB1	P53778	MAPK12	S33	G34C	34	Missense	proximal	1	no	120.324	-53.523	EPSD	COSMIC	112.929	Loss
CMGC_MAPK_p38_MAPK12_ST	P35222	CTNNB1	P53778	MAPK12	S33	G38S	38	Missense	distal	5	no	120.324	120.898	EPSD	COSMIC	112.929	Up-regulation
CMGC_MAPK_p38_MAPK12_ST	P35222	CTNNB1	P53778	MAPK12	S33	S37V	37	Missense	distal	4	no	120.324	119.446	EPSD	COSMIC	112.929	Down-regulation
CMGC_MAPK_p38_MAPK12_ST	P35222	CTNNB1	P53778	MAPK12	S33	I35F	35	Missense	proximal	2	no	120.324	118.865	EPSD	COSMIC	112.929	Down-regulation
CMGC_MAPK_p38_MAPK12_ST	P35222	CTNNB1	P53778	MAPK12	S33	T40P	40	Missense	distal	7	no	120.324	120.453	EPSD	COSMIC	112.929	Up-regulation
CMGC_MAPK_p38_MAPK12_ST	P35222	CTNNB1	P53778	MAPK12	S37	G38P	38	Missense	proximal	1	no	109.291	125.670	EPSD	COSMIC	112.929	Gain
CMGC_MAPK_p38_MAPK12_ST	P35222	CTNNB1	P53778	MAPK12	T40	T41P	41	Missense	proximal	1	no	5.403	136.615	EPSD	COSMIC	112.929	Gain
CMGC_MAPK_p38_MAPK12_ST	P35222	CTNNB1	P53778	MAPK12	T42	A43P	43	Missense	proximal	1	no	45.405	130.550	EPSD	COSMIC	112.929	Gain
CMGC_MAPK_p38_MAPK12_ST	P35222	CTNNB1	P53778	MAPK12	S45	A39T	39	Missense	distal	-6	no	111.386	113.059	EPSD	COSMIC	112.929	Gain
CMGC_MAPK_p38_MAPK12_ST	P35222	CTNNB1	P53778	MAPK12	S45	A43P	43	Missense	proximal	-2	no	111.386	115.436	EPSD	COSMIC	112.929	Gain
CMGC_MAPK_p38_MAPK12_ST	P35222	CTNNB1	P53778	MAPK12	S45	L46P	46	Missense	proximal	1	no	111.386	128.131	EPSD	COSMIC	112.929	Gain
CMGC_MAPK_p38_MAPK12_ST	P35222	CTNNB1	P53778	MAPK12	S45	T41S	41	Missense	distal	-4	no	111.386	114.870	EPSD	COSMIC	112.929	Gain
CMGC_MAPK_p38_MAPK12_ST	P35222	CTNNB1	P53778	MAPK12	S45	A39V	39	Missense	distal	-6	no	111.386	114.019	EPSD	COSMIC	112.929	Gain
CMGC_MAPK_p38_MAPK12_ST	P35222	CTNNB1	P53778	MAPK12	S47	E53K	53	Missense	distal	6	no	112.459	113.078	EPSD	COSMIC	112.929	Gain
CMGC_MAPK_p38_MAPK12_ST	P35222	CTNNB1	P53778	MAPK12	S47	E54K	54	Missense	distal	7	no	112.459	113.984	EPSD	COSMIC	112.929	Gain
CMGC_MAPK_p38_MAPK12_ST	P35222	CTNNB1	P53778	MAPK12	S47	A43T	43	Missense	distal	-4	no	112.459	113.016	EPSD	COSMIC	112.929	Gain
CMGC_MAPK_p38_MAPK12_ST	P35222	CTNNB1	P53778	MAPK12	S47	E54G	54	Missense	distal	7	no	112.459	113.838	EPSD	COSMIC	112.929	Gain
CMGC_MAPK_p38_MAPK12_ST	P35222	CTNNB1	P53778	MAPK12	S47	G50D	50	Missense	distal	3	no	112.459	113.330	EPSD	COSMIC	112.929	Gain
CMGC_MAPK_p38_MAPK12_ST	P35222	CTNNB1	P53778	MAPK12	S47	L46P	46	Missense	proximal	-1	no	112.459	113.346	EPSD	COSMIC	112.929	Gain
CMGC_MAPK_p38_MAPK12_ST	P35222	CTNNB1	P53778	MAPK12	S60	Q61L	61	Missense	proximal	1	no	-58.528	122.734	EPSD	COSMIC	112.929	Gain
CMGC_MAPK_p38_MAPK12_ST	P35222	CTNNB1	P53778	MAPK12	T102	Q108H	108	Missense	distal	6	no	113.879	114.018	EPSD	COSMIC	112.929	Up-regulation
CMGC_MAPK_p38_MAPK12_ST	P35222	CTNNB1	P53778	MAPK12	T102	D104Y	104	Missense	proximal	2	no	113.879	113.513	EPSD	COSMIC	112.929	Down-regulation
CMGC_MAPK_p38_MAPK12_ST	P35222	CTNNB1	P53778	MAPK12	T102	P100H	100	Missense	proximal	-2	no	113.879	106.028	EPSD	COSMIC	112.929	Loss
CMGC_MAPK_p38_MAPK12_ST	P35222	CTNNB1	P53778	MAPK12	T102	P100L	100	Missense	proximal	-2	no	113.879	108.223	EPSD	COSMIC	112.929	Loss
CMGC_MAPK_p38_MAPK12_ST	P35222	CTNNB1	P53778	MAPK12	T102	R95G	95	Missense	distal	-7	no	113.879	113.581	EPSD	COSMIC	112.929	Down-regulation
CMGC_MAPK_p38_MAPK12_ST	P35222	CTNNB1	P53778	MAPK12	T102	R95S	95	Missense	distal	-7	no	113.879	112.379	EPSD	COSMIC	112.929	Loss
CMGC_MAPK_p38_MAPK12_ST	P35222	CTNNB1	P53778	MAPK12	T102	F99L	99	Missense	distal	-3	no	113.879	114.333	EPSD	COSMIC	112.929	Up-regulation
CMGC_MAPK_p38_MAPK12_ST	P35222	CTNNB1	P53778	MAPK12	S191	P192S	192	Missense	proximal	1	no	120.489	50.003	EPSD	COSMIC	112.929	Loss
CMGC_MAPK_p38_MAPK12_ST	P35222	CTNNB1	P53778	MAPK12	S191	A187T	187	Missense	distal	-4	no	120.489	121.045	EPSD	COSMIC	112.929	Up-regulation
CMGC_MAPK_p38_MAPK12_ST	P35222	CTNNB1	P53778	MAPK12	S191	R190C	190	Missense	proximal	-1	no	120.489	119.305	EPSD	COSMIC	112.929	Down-regulation
CMGC_MAPK_p38_MAPK12_ST	P35222	CTNNB1	P53778	MAPK12	S191	A187D	187	Missense	distal	-4	no	120.489	128.368	EPSD	COSMIC	112.929	Up-regulation
CMGC_MAPK_p38_MAPK12_ST	P35222	CTNNB1	P53778	MAPK12	S191	P192H	192	Missense	proximal	1	no	120.489	-13.326	EPSD	COSMIC	112.929	Loss
CMGC_MAPK_p38_MAPK12_ST	P35222	CTNNB1	P53778	MAPK12	S191	I188M	188	Missense	distal	-3	no	120.489	119.962	EPSD	COSMIC	112.929	Down-regulation
CMGC_MAPK_p38_MAPK12_ST	P35222	CTNNB1	P53778	MAPK12	S191	R190H	190	Missense	proximal	-1	no	120.489	120.585	EPSD	COSMIC	112.929	Up-regulation
CMGC_MAPK_p38_MAPK12_ST	P35222	CTNNB1	P53778	MAPK12	S191	I198L	198	Missense	distal	7	no	120.489	118.896	EPSD	COSMIC	112.929	Down-regulation
CMGC_MAPK_p38_MAPK12_ST	P35222	CTNNB1	P53778	MAPK12	S191	A187V	187	Missense	distal	-4	no	120.489	115.331	EPSD	COSMIC	112.929	Down-regulation
CMGC_MAPK_p38_MAPK12_ST	P35222	CTNNB1	P53778	MAPK12	S191	R185K	185	Missense	distal	-6	no	120.489	118.794	EPSD	COSMIC	112.929	Down-regulation
CMGC_MAPK_p38_MAPK12_ST	P35222	CTNNB1	P53778	MAPK12	S246	M243T	243	Missense	distal	-3	no	128.327	128.542	EPSD	COSMIC	112.929	Up-regulation
CMGC_MAPK_p38_MAPK12_ST	P35222	CTNNB1	P53778	MAPK12	S246	S246L	246	Missense	central	0	yes	128.327	0.000	EPSD	COSMIC	112.929	Loss
CMGC_MAPK_p38_MAPK12_ST	P35222	CTNNB1	P53778	MAPK12	S246	G245A	245	Missense	proximal	-1	no	128.327	127.754	EPSD	COSMIC;GDSC	112.929	Down-regulation
CMGC_MAPK_p38_MAPK12_ST	P35222	CTNNB1	P53778	MAPK12	S246	G245D	245	Missense	proximal	-1	no	128.327	129.030	EPSD	COSMIC	112.929	Up-regulation
CMGC_MAPK_p38_MAPK12_ST	P35222	CTNNB1	P53778	MAPK12	S246	A239V	239	Missense	distal	-7	no	128.327	130.571	EPSD	COSMIC	112.929	Up-regulation
CMGC_MAPK_p38_MAPK12_ST	P35222	CTNNB1	P53778	MAPK12	S246	K242E	242	Missense	distal	-4	no	128.327	125.855	EPSD	COSMIC	112.929	Down-regulation
CMGC_MAPK_p38_MAPK12_ST	P35222	CTNNB1	P53778	MAPK12	S246	A239G	239	Missense	distal	-7	no	128.327	129.673	EPSD	COSMIC	112.929	Up-regulation
CMGC_MAPK_p38_MAPK12_ST	P35222	CTNNB1	P53778	MAPK12	T258	T257I	257	Missense	proximal	-1	no	117.276	117.887	EPSD	COSMIC	112.929	Up-regulation
CMGC_MAPK_p38_MAPK12_ST	P35222	CTNNB1	P53778	MAPK12	T258	A255T	255	Missense	distal	-3	no	117.276	117.191	EPSD	COSMIC	112.929	Down-regulation
CMGC_MAPK_p38_MAPK12_ST	P35222	CTNNB1	P53778	MAPK12	T258	L264H	264	Missense	distal	6	no	117.276	117.223	EPSD	COSMIC	112.929	Down-regulation
CMGC_MAPK_p38_MAPK12_ST	P35222	CTNNB1	P53778	MAPK12	S605	V600G	600	Missense	distal	-5	no	132.393	132.612	PhosphoSitePlus	COSMIC	112.929	Up-regulation
CMGC_MAPK_p38_MAPK12_ST	P35222	CTNNB1	P53778	MAPK12	S605	R612T	612	Missense	distal	7	no	132.393	132.871	PhosphoSitePlus	COSMIC	112.929	Up-regulation
CMGC_MAPK_p38_MAPK12_ST	P35222	CTNNB1	P53778	MAPK12	S605	V600L	600	Missense	distal	-5	no	132.393	132.350	PhosphoSitePlus	COSMIC;GDSC;CCLE	112.929	Down-regulation
CMGC_MAPK_p38_MAPK12_ST	P35222	CTNNB1	P53778	MAPK12	S605	V600A	600	Missense	distal	-5	no	132.393	132.644	PhosphoSitePlus	COSMIC	112.929	Up-regulation
CMGC_MAPK_p38_MAPK12_ST	P35222	CTNNB1	P53778	MAPK12	S605	F599L	599	Missense	distal	-6	no	132.393	131.880	PhosphoSitePlus	COSMIC	112.929	Down-regulation
CMGC_MAPK_p38_MAPK12_ST	P35222	CTNNB1	P53778	MAPK12	S605	Q611R	611	Missense	distal	6	no	132.393	132.383	PhosphoSitePlus	COSMIC	112.929	Down-regulation
CMGC_MAPK_p38_MAPK12_ST	P35222	CTNNB1	P53778	MAPK12	S605	L603R	603	Missense	proximal	-2	no	132.393	127.382	PhosphoSitePlus	COSMIC	112.929	Down-regulation
CMGC_MAPK_p38_MAPK12_ST	P35222	CTNNB1	P53778	MAPK12	S605	L603Q	603	Missense	proximal	-2	no	132.393	127.766	PhosphoSitePlus	COSMIC	112.929	Down-regulation
CMGC_MAPK_p38_MAPK12_ST	P10636	MAPT	P53778	MAPK12	T69	E62K	62	Missense	distal	-7	no	139.605	137.904	EPSD	COSMIC	112.929	Down-regulation
CMGC_MAPK_p38_MAPK12_ST	P10636	MAPT	P53778	MAPK12	T111	I108V	108	Missense	distal	-3	no	138.577	137.787	EPSD	COSMIC	112.929	Down-regulation
CMGC_MAPK_p38_MAPK12_ST	P10636	MAPT	P53778	MAPK12	T111	G107R	107	Missense	distal	-4	no	138.577	132.591	EPSD	COSMIC	112.929	Down-regulation
CMGC_MAPK_p38_MAPK12_ST	P10636	MAPT	P53778	MAPK12	T173	A166V	166	Missense	distal	-7	no	111.360	113.604	EPSD	COSMIC;CCLE	112.929	Gain
CMGC_MAPK_p38_MAPK12_ST	P10636	MAPT	P53778	MAPK12	S228	S227N	227	Missense	proximal	-1	no	119.197	118.525	EPSD	COSMIC	112.929	Down-regulation
CMGC_MAPK_p38_MAPK12_ST	P10636	MAPT	P53778	MAPK12	S228	S227I	227	Missense	proximal	-1	no	119.197	118.676	EPSD	COSMIC	112.929	Down-regulation
CMGC_MAPK_p38_MAPK12_ST	P10636	MAPT	P53778	MAPK12	S228	E226K	226	Missense	proximal	-2	no	119.197	124.666	EPSD	COSMIC	112.929	Up-regulation
CMGC_MAPK_p38_MAPK12_ST	P10636	MAPT	P53778	MAPK12	S228	Q230R	230	Missense	proximal	2	no	119.197	119.489	EPSD	COSMIC	112.929	Up-regulation
CMGC_MAPK_p38_MAPK12_ST	P10636	MAPT	P53778	MAPK12	S228	P233S	233	Missense	distal	5	no	119.197	119.952	EPSD	COSMIC	112.929	Up-regulation
CMGC_MAPK_p38_MAPK12_ST	P10636	MAPT	P53778	MAPK12	S228	D225E	225	Missense	distal	-3	no	119.197	118.012	EPSD	COSMIC	112.929	Down-regulation
CMGC_MAPK_p38_MAPK12_ST	P10636	MAPT	P53778	MAPK12	S228	S227G	227	Missense	proximal	-1	no	119.197	118.831	EPSD	COSMIC	112.929	Down-regulation
CMGC_MAPK_p38_MAPK12_ST	P10636	MAPT	P53778	MAPK12	S228	S235L	235	Missense	distal	7	no	119.197	117.637	EPSD	COSMIC	112.929	Down-regulation
CMGC_MAPK_p38_MAPK12_ST	P10636	MAPT	P53778	MAPK12	S232	S227N	227	Missense	distal	-5	no	127.513	127.527	EPSD	COSMIC	112.929	Up-regulation
CMGC_MAPK_p38_MAPK12_ST	P10636	MAPT	P53778	MAPK12	S232	S227I	227	Missense	distal	-5	no	127.513	127.491	EPSD	COSMIC	112.929	Down-regulation
CMGC_MAPK_p38_MAPK12_ST	P10636	MAPT	P53778	MAPK12	S232	A237T	237	Missense	distal	5	no	127.513	127.460	EPSD	COSMIC	112.929	Down-regulation
CMGC_MAPK_p38_MAPK12_ST	P10636	MAPT	P53778	MAPK12	S232	E226K	226	Missense	distal	-6	no	127.513	125.251	EPSD	COSMIC	112.929	Down-regulation
CMGC_MAPK_p38_MAPK12_ST	P10636	MAPT	P53778	MAPK12	S232	Q230R	230	Missense	proximal	-2	no	127.513	127.129	EPSD	COSMIC	112.929	Down-regulation
CMGC_MAPK_p38_MAPK12_ST	P10636	MAPT	P53778	MAPK12	S232	S238P	238	Missense	distal	6	no	127.513	127.208	EPSD	COSMIC	112.929	Down-regulation
CMGC_MAPK_p38_MAPK12_ST	P10636	MAPT	P53778	MAPK12	S232	P233S	233	Missense	proximal	1	no	127.513	57.027	EPSD	COSMIC	112.929	Loss
CMGC_MAPK_p38_MAPK12_ST	P10636	MAPT	P53778	MAPK12	S232	S238F	238	Missense	distal	6	no	127.513	126.119	EPSD	COSMIC	112.929	Down-regulation
CMGC_MAPK_p38_MAPK12_ST	P10636	MAPT	P53778	MAPK12	S232	D225E	225	Missense	distal	-7	no	127.513	130.180	EPSD	COSMIC	112.929	Up-regulation
CMGC_MAPK_p38_MAPK12_ST	P10636	MAPT	P53778	MAPK12	S232	S227G	227	Missense	distal	-5	no	127.513	127.460	EPSD	COSMIC	112.929	Down-regulation
CMGC_MAPK_p38_MAPK12_ST	P10636	MAPT	P53778	MAPK12	S232	S235L	235	Missense	distal	3	no	127.513	126.683	EPSD	COSMIC	112.929	Down-regulation
CMGC_MAPK_p38_MAPK12_ST	P10636	MAPT	P53778	MAPK12	S238	A237T	237	Missense	proximal	-1	no	124.422	124.228	EPSD	COSMIC	112.929	Down-regulation
CMGC_MAPK_p38_MAPK12_ST	P10636	MAPT	P53778	MAPK12	S238	A240S	240	Missense	proximal	2	no	124.422	124.635	EPSD	COSMIC	112.929	Up-regulation
CMGC_MAPK_p38_MAPK12_ST	P10636	MAPT	P53778	MAPK12	S238	D242N	242	Missense	distal	4	no	124.422	123.829	EPSD	COSMIC	112.929	Down-regulation
CMGC_MAPK_p38_MAPK12_ST	P10636	MAPT	P53778	MAPK12	S238	R244W	244	Missense	distal	6	no	124.422	124.573	EPSD	COSMIC	112.929	Up-regulation
CMGC_MAPK_p38_MAPK12_ST	P10636	MAPT	P53778	MAPK12	S238	S238P	238	Missense	central	0	yes	124.422	0.000	EPSD	COSMIC	112.929	Loss
CMGC_MAPK_p38_MAPK12_ST	P10636	MAPT	P53778	MAPK12	S238	P233S	233	Missense	distal	-5	no	124.422	124.466	EPSD	COSMIC	112.929	Up-regulation
CMGC_MAPK_p38_MAPK12_ST	P10636	MAPT	P53778	MAPK12	S238	S238F	238	Missense	central	0	yes	124.422	0.000	EPSD	COSMIC	112.929	Loss
CMGC_MAPK_p38_MAPK12_ST	P10636	MAPT	P53778	MAPK12	S238	G243D	243	Missense	distal	5	no	124.422	124.875	EPSD	COSMIC	112.929	Up-regulation
CMGC_MAPK_p38_MAPK12_ST	P10636	MAPT	P53778	MAPK12	S238	S235L	235	Missense	distal	-3	no	124.422	123.740	EPSD	COSMIC	112.929	Down-regulation
CMGC_MAPK_p38_MAPK12_ST	P10636	MAPT	P53778	MAPK12	T386	G385V	385	Missense	proximal	-1	no	114.896	112.858	EPSD	COSMIC	112.929	Loss
CMGC_MAPK_p38_MAPK12_ST	P10636	MAPT	P53778	MAPK12	T386	T386I	386	Missense	central	0	yes	114.896	0.000	EPSD	COSMIC	112.929	Loss
CMGC_MAPK_p38_MAPK12_ST	P10636	MAPT	P53778	MAPK12	T386	D389N	389	Missense	distal	3	no	114.896	114.233	EPSD	COSMIC;GDSC;CCLE	112.929	Down-regulation
CMGC_MAPK_p38_MAPK12_ST	P10636	MAPT	P53778	MAPK12	T403	L410F	410	Missense	distal	7	no	126.500	126.482	EPSD	COSMIC	112.929	Down-regulation
CMGC_MAPK_p38_MAPK12_ST	P10636	MAPT	P53778	MAPK12	T403	R398C	398	Missense	distal	-5	no	126.500	126.381	EPSD	COSMIC	112.929	Down-regulation
CMGC_MAPK_p38_MAPK12_ST	P10636	MAPT	P53778	MAPK12	T403	S396F	396	Missense	distal	-7	no	126.500	129.034	EPSD	COSMIC	112.929	Up-regulation
CMGC_MAPK_p38_MAPK12_ST	P10636	MAPT	P53778	MAPK12	S411	L410F	410	Missense	proximal	-1	no	133.123	131.708	EPSD	COSMIC	112.929	Down-regulation
CMGC_MAPK_p38_MAPK12_ST	P10636	MAPT	P53778	MAPK12	S411	P412S	412	Missense	proximal	1	no	133.123	62.638	EPSD	COSMIC	112.929	Loss
CMGC_MAPK_p38_MAPK12_ST	P10636	MAPT	P53778	MAPK12	T416	L410F	410	Missense	distal	-6	no	123.640	124.153	EPSD	COSMIC	112.929	Up-regulation
CMGC_MAPK_p38_MAPK12_ST	P10636	MAPT	P53778	MAPK12	T416	P412S	412	Missense	distal	-4	no	123.640	127.716	EPSD	COSMIC	112.929	Up-regulation
CMGC_MAPK_p38_MAPK12_ST	P10636	MAPT	P53778	MAPK12	S438	S443Y	443	Missense	distal	5	no	130.470	129.789	EPSD	COSMIC	112.929	Down-regulation
CMGC_MAPK_p38_MAPK12_ST	P10636	MAPT	P53778	MAPK12	T449	S447P	447	Missense	proximal	-2	no	111.333	114.282	EPSD	COSMIC	112.929	Gain
CMGC_MAPK_p38_MAPK12_ST	P10636	MAPT	P53778	MAPK12	T470	T466M	466	Missense	distal	-4	no	129.712	127.460	EPSD	COSMIC;GDSC;CCLE	112.929	Down-regulation
CMGC_MAPK_p38_MAPK12_ST	P10636	MAPT	P53778	MAPK12	T470	K467T	467	Missense	distal	-3	no	129.712	129.757	EPSD	COSMIC	112.929	Up-regulation
CMGC_MAPK_p38_MAPK12_ST	P10636	MAPT	P53778	MAPK12	T470	P477L	477	Missense	distal	7	no	129.712	128.673	EPSD	COSMIC	112.929	Down-regulation
CMGC_MAPK_p38_MAPK12_ST	P10636	MAPT	P53778	MAPK12	T470	P477S	477	Missense	distal	7	no	129.712	130.233	EPSD	COSMIC	112.929	Up-regulation
CMGC_MAPK_p38_MAPK12_ST	P10636	MAPT	P53778	MAPK12	T486	R487G	487	Missense	proximal	1	no	-54.472	114.894	EPSD	COSMIC	112.929	Gain
CMGC_MAPK_p38_MAPK12_ST	P10636	MAPT	P53778	MAPK12	T492	R487K	487	Missense	distal	-5	no	133.001	133.170	EPSD	COSMIC	112.929	Up-regulation
CMGC_MAPK_p38_MAPK12_ST	P10636	MAPT	P53778	MAPK12	T492	K491R	491	Missense	proximal	-1	no	133.001	132.348	EPSD	COSMIC	112.929	Down-regulation
CMGC_MAPK_p38_MAPK12_ST	P10636	MAPT	P53778	MAPK12	T492	R487G	487	Missense	distal	-5	no	133.001	133.198	EPSD	COSMIC	112.929	Up-regulation
CMGC_MAPK_p38_MAPK12_ST	P10636	MAPT	P53778	MAPK12	T492	A495T	495	Missense	distal	3	no	133.001	132.700	EPSD	COSMIC	112.929	Down-regulation
CMGC_MAPK_p38_MAPK12_ST	P10636	MAPT	P53778	MAPK12	T492	P493L	493	Missense	proximal	1	no	133.001	116.256	EPSD	COSMIC	112.929	Down-regulation
CMGC_MAPK_p38_MAPK12_ST	P10636	MAPT	P53778	MAPK12	T498	K491R	491	Missense	distal	-7	no	131.414	132.423	EPSD	COSMIC	112.929	Up-regulation
CMGC_MAPK_p38_MAPK12_ST	P10636	MAPT	P53778	MAPK12	T498	A495T	495	Missense	distal	-3	no	131.414	131.330	EPSD	COSMIC	112.929	Down-regulation
CMGC_MAPK_p38_MAPK12_ST	P10636	MAPT	P53778	MAPK12	T498	P493L	493	Missense	distal	-5	no	131.414	131.144	EPSD	COSMIC	112.929	Down-regulation
CMGC_MAPK_p38_MAPK12_ST	P10636	MAPT	P53778	MAPK12	S502	P506S	506	Missense	distal	4	no	115.112	115.372	EPSD	COSMIC	112.929	Up-regulation
CMGC_MAPK_p38_MAPK12_ST	P10636	MAPT	P53778	MAPK12	S502	A495T	495	Missense	distal	-7	no	115.112	116.239	EPSD	COSMIC	112.929	Up-regulation
CMGC_MAPK_p38_MAPK12_ST	P10636	MAPT	P53778	MAPK12	S502	G509V	509	Missense	distal	7	no	115.112	114.382	EPSD	COSMIC	112.929	Down-regulation
CMGC_MAPK_p38_MAPK12_ST	P10636	MAPT	P53778	MAPK12	S502	P506L	506	Missense	distal	4	no	115.112	114.564	EPSD	COSMIC	112.929	Down-regulation
CMGC_MAPK_p38_MAPK12_ST	P10636	MAPT	P53778	MAPK12	S508	P506S	506	Missense	proximal	-2	no	114.644	111.695	EPSD	COSMIC	112.929	Loss
CMGC_MAPK_p38_MAPK12_ST	P10636	MAPT	P53778	MAPK12	S508	R511C	511	Missense	distal	3	no	114.644	114.454	EPSD	COSMIC;CCLE	112.929	Down-regulation
CMGC_MAPK_p38_MAPK12_ST	P10636	MAPT	P53778	MAPK12	S508	G509V	509	Missense	proximal	1	no	114.644	52.972	EPSD	COSMIC	112.929	Loss
CMGC_MAPK_p38_MAPK12_ST	P10636	MAPT	P53778	MAPK12	S508	P506L	506	Missense	proximal	-2	no	114.644	108.989	EPSD	COSMIC	112.929	Loss
CMGC_MAPK_p38_MAPK12_ST	P10636	MAPT	P53778	MAPK12	S512	P506S	506	Missense	distal	-6	no	126.606	126.576	EPSD	COSMIC	112.929	Down-regulation
CMGC_MAPK_p38_MAPK12_ST	P10636	MAPT	P53778	MAPK12	S512	G518V	518	Missense	distal	6	no	126.606	125.741	EPSD	COSMIC	112.929	Down-regulation
CMGC_MAPK_p38_MAPK12_ST	P10636	MAPT	P53778	MAPK12	S512	R511C	511	Missense	proximal	-1	no	126.606	125.421	EPSD	COSMIC;CCLE	112.929	Down-regulation
CMGC_MAPK_p38_MAPK12_ST	P10636	MAPT	P53778	MAPK12	S512	G509V	509	Missense	distal	-3	no	126.606	125.952	EPSD	COSMIC	112.929	Down-regulation
CMGC_MAPK_p38_MAPK12_ST	P10636	MAPT	P53778	MAPK12	S512	P506L	506	Missense	distal	-6	no	126.606	129.628	EPSD	COSMIC	112.929	Up-regulation
CMGC_MAPK_p38_MAPK12_ST	P10636	MAPT	P53778	MAPK12	S516	G521V	521	Missense	distal	5	no	144.771	143.613	EPSD	COSMIC	112.929	Down-regulation
CMGC_MAPK_p38_MAPK12_ST	P10636	MAPT	P53778	MAPK12	S516	G518V	518	Missense	proximal	2	no	144.771	144.263	EPSD	COSMIC	112.929	Down-regulation
CMGC_MAPK_p38_MAPK12_ST	P10636	MAPT	P53778	MAPK12	S516	R511C	511	Missense	distal	-5	no	144.771	144.652	EPSD	COSMIC;CCLE	112.929	Down-regulation
CMGC_MAPK_p38_MAPK12_ST	P10636	MAPT	P53778	MAPK12	S516	G509V	509	Missense	distal	-7	no	144.771	145.669	EPSD	COSMIC	112.929	Up-regulation
CMGC_MAPK_p38_MAPK12_ST	P10636	MAPT	P53778	MAPK12	S519	G521V	521	Missense	proximal	2	no	138.829	138.321	EPSD	COSMIC	112.929	Down-regulation
CMGC_MAPK_p38_MAPK12_ST	P10636	MAPT	P53778	MAPK12	S519	R526H	526	Missense	distal	7	no	138.829	138.687	EPSD	COSMIC	112.929	Down-regulation
CMGC_MAPK_p38_MAPK12_ST	P10636	MAPT	P53778	MAPK12	S519	G518V	518	Missense	proximal	-1	no	138.829	136.791	EPSD	COSMIC	112.929	Down-regulation
CMGC_MAPK_p38_MAPK12_ST	P10636	MAPT	P53778	MAPK12	T522	G521V	521	Missense	proximal	-1	no	140.094	138.056	EPSD	COSMIC	112.929	Down-regulation
CMGC_MAPK_p38_MAPK12_ST	P10636	MAPT	P53778	MAPK12	T522	R526H	526	Missense	distal	4	no	140.094	140.215	EPSD	COSMIC	112.929	Up-regulation
CMGC_MAPK_p38_MAPK12_ST	P10636	MAPT	P53778	MAPK12	T522	G518V	518	Missense	distal	-4	no	140.094	131.591	EPSD	COSMIC	112.929	Down-regulation
CMGC_MAPK_p38_MAPK12_ST	P10636	MAPT	P53778	MAPK12	T522	R528S	528	Missense	distal	6	no	140.094	140.955	EPSD	COSMIC	112.929	Up-regulation
CMGC_MAPK_p38_MAPK12_ST	P10636	MAPT	P53778	MAPK12	T529	R526H	526	Missense	distal	-3	no	138.918	139.050	EPSD	COSMIC	112.929	Up-regulation
CMGC_MAPK_p38_MAPK12_ST	P10636	MAPT	P53778	MAPK12	T529	R528S	528	Missense	proximal	-1	no	138.918	140.847	EPSD	COSMIC	112.929	Up-regulation
CMGC_MAPK_p38_MAPK12_ST	P10636	MAPT	P53778	MAPK12	T529	P530S	530	Missense	proximal	1	no	138.918	68.432	EPSD	COSMIC	112.929	Loss
CMGC_MAPK_p38_MAPK12_ST	P10636	MAPT	P53778	MAPK12	T529	P536H	536	Missense	distal	7	no	138.918	138.169	EPSD	COSMIC	112.929	Down-regulation
CMGC_MAPK_p38_MAPK12_ST	P10636	MAPT	P53778	MAPK12	T529	P535Q	535	Missense	distal	6	no	138.918	138.372	EPSD	COSMIC	112.929	Down-regulation
CMGC_MAPK_p38_MAPK12_ST	P10636	MAPT	P53778	MAPK12	S531	R526H	526	Missense	distal	-5	no	115.782	115.826	EPSD	COSMIC	112.929	Up-regulation
CMGC_MAPK_p38_MAPK12_ST	P10636	MAPT	P53778	MAPK12	S531	R528S	528	Missense	distal	-3	no	115.782	116.450	EPSD	COSMIC	112.929	Up-regulation
CMGC_MAPK_p38_MAPK12_ST	P10636	MAPT	P53778	MAPK12	S531	P530S	530	Missense	proximal	-1	no	115.782	116.839	EPSD	COSMIC	112.929	Up-regulation
CMGC_MAPK_p38_MAPK12_ST	P10636	MAPT	P53778	MAPK12	S531	P536H	536	Missense	distal	5	no	115.782	114.955	EPSD	COSMIC	112.929	Down-regulation
CMGC_MAPK_p38_MAPK12_ST	P10636	MAPT	P53778	MAPK12	S531	P535Q	535	Missense	distal	4	no	115.782	114.847	EPSD	COSMIC	112.929	Down-regulation
CMGC_MAPK_p38_MAPK12_ST	P10636	MAPT	P53778	MAPK12	T534	R528S	528	Missense	distal	-6	no	134.506	131.958	EPSD	COSMIC	112.929	Down-regulation
CMGC_MAPK_p38_MAPK12_ST	P10636	MAPT	P53778	MAPK12	T534	P530S	530	Missense	distal	-4	no	134.506	138.582	EPSD	COSMIC	112.929	Up-regulation
CMGC_MAPK_p38_MAPK12_ST	P10636	MAPT	P53778	MAPK12	T534	P536H	536	Missense	proximal	2	no	134.506	133.954	EPSD	COSMIC	112.929	Down-regulation
CMGC_MAPK_p38_MAPK12_ST	P10636	MAPT	P53778	MAPK12	T534	P535Q	535	Missense	proximal	1	no	134.506	-63.502	EPSD	COSMIC	112.929	Loss
CMGC_MAPK_p38_MAPK12_ST	P10636	MAPT	P53778	MAPK12	T534	E539Q	539	Missense	distal	5	no	134.506	134.738	EPSD	COSMIC	112.929	Up-regulation
CMGC_MAPK_p38_MAPK12_ST	P10636	MAPT	P53778	MAPK12	T548	P550S	550	Missense	proximal	2	no	122.151	122.534	EPSD	COSMIC	112.929	Up-regulation
CMGC_MAPK_p38_MAPK12_ST	P10636	MAPT	P53778	MAPK12	T548	P553R	553	Missense	distal	5	no	122.151	121.495	EPSD	COSMIC	112.929	Down-regulation
CMGC_MAPK_p38_MAPK12_ST	P10636	MAPT	P53778	MAPK12	T548	P553L	553	Missense	distal	5	no	122.151	121.455	EPSD	COSMIC	112.929	Down-regulation
CMGC_MAPK_p38_MAPK12_ST	P10636	MAPT	P53778	MAPK12	T548	P549L	549	Missense	proximal	1	no	122.151	105.406	EPSD	COSMIC	112.929	Loss
CMGC_MAPK_p38_MAPK12_ST	P10636	MAPT	P53778	MAPK12	T548	S555F	555	Missense	distal	7	no	122.151	120.573	EPSD	COSMIC	112.929	Down-regulation
CMGC_MAPK_p38_MAPK12_ST	P10636	MAPT	P53778	MAPK12	T548	P553Q	553	Missense	distal	5	no	122.151	121.185	EPSD	COSMIC	112.929	Down-regulation
CMGC_MAPK_p38_MAPK12_ST	P10636	MAPT	P53778	MAPK12	S552	P550S	550	Missense	proximal	-2	no	133.976	131.028	EPSD	COSMIC	112.929	Down-regulation
CMGC_MAPK_p38_MAPK12_ST	P10636	MAPT	P53778	MAPK12	S552	R559C	559	Missense	distal	7	no	133.976	133.281	EPSD	COSMIC	112.929	Down-regulation
CMGC_MAPK_p38_MAPK12_ST	P10636	MAPT	P53778	MAPK12	S552	P553R	553	Missense	proximal	1	no	133.976	-51.768	EPSD	COSMIC	112.929	Loss
CMGC_MAPK_p38_MAPK12_ST	P10636	MAPT	P53778	MAPK12	S552	P553L	553	Missense	proximal	1	no	133.976	117.230	EPSD	COSMIC	112.929	Down-regulation
CMGC_MAPK_p38_MAPK12_ST	P10636	MAPT	P53778	MAPK12	S552	P549L	549	Missense	distal	-3	no	133.976	133.515	EPSD	COSMIC	112.929	Down-regulation
CMGC_MAPK_p38_MAPK12_ST	P10636	MAPT	P53778	MAPK12	S552	S555F	555	Missense	distal	3	no	133.976	132.927	EPSD	COSMIC	112.929	Down-regulation
CMGC_MAPK_p38_MAPK12_ST	P10636	MAPT	P53778	MAPK12	S552	P553Q	553	Missense	proximal	1	no	133.976	-64.032	EPSD	COSMIC	112.929	Loss
CMGC_MAPK_p38_MAPK12_ST	P10636	MAPT	P53778	MAPK12	S673	V680I	680	Missense	distal	7	no	122.446	123.415	EPSD	COSMIC	112.929	Up-regulation
CMGC_MAPK_p38_MAPK12_ST	P10636	MAPT	P53778	MAPK12	S673	S669L	669	Missense	distal	-4	no	122.446	116.570	EPSD	COSMIC	112.929	Down-regulation
CMGC_MAPK_p38_MAPK12_ST	P10636	MAPT	P53778	MAPK12	S673	R666K	666	Missense	distal	-7	no	122.446	121.438	EPSD	COSMIC	112.929	Down-regulation
CMGC_MAPK_p38_MAPK12_ST	P10636	MAPT	P53778	MAPK12	S673	S673F	673	Missense	central	0	yes	122.446	0.000	EPSD	COSMIC	112.929	Loss
CMGC_MAPK_p38_MAPK12_ST	P10636	MAPT	P53778	MAPK12	S673	K670N	670	Missense	distal	-3	no	122.446	122.614	EPSD	COSMIC	112.929	Up-regulation
CMGC_MAPK_p38_MAPK12_ST	P10636	MAPT	P53778	MAPK12	S673	L674Q	674	Missense	proximal	1	no	122.446	-58.816	EPSD	COSMIC	112.929	Loss
CMGC_MAPK_p38_MAPK12_ST	P10636	MAPT	P53778	MAPK12	S713	E708D	708	Missense	distal	-5	no	134.253	134.625	EPSD	COSMIC	112.929	Up-regulation
CMGC_MAPK_p38_MAPK12_ST	P10636	MAPT	P53778	MAPK12	S713	G706R	706	Missense	distal	-7	no	134.253	134.550	EPSD	COSMIC	112.929	Up-regulation
CMGC_MAPK_p38_MAPK12_ST	P10636	MAPT	P53778	MAPK12	S713	V710M	710	Missense	distal	-3	no	134.253	134.516	EPSD	COSMIC	112.929	Up-regulation
CMGC_MAPK_p38_MAPK12_ST	P10636	MAPT	P53778	MAPK12	S713	E708K	708	Missense	distal	-5	no	134.253	134.483	EPSD	COSMIC	112.929	Up-regulation
CMGC_MAPK_p38_MAPK12_ST	P10636	MAPT	P53778	MAPK12	S713	V710A	710	Missense	distal	-3	no	134.253	134.816	EPSD	COSMIC	112.929	Up-regulation
CMGC_MAPK_p38_MAPK12_ST	P10636	MAPT	P53778	MAPK12	S721	R723W	723	Missense	proximal	2	no	135.760	135.720	EPSD	COSMIC	112.929	Down-regulation
CMGC_MAPK_p38_MAPK12_ST	P10636	MAPT	P53778	MAPK12	S721	V728M	728	Missense	distal	7	no	135.760	135.530	EPSD	COSMIC	112.929	Down-regulation
CMGC_MAPK_p38_MAPK12_ST	P10636	MAPT	P53778	MAPK12	S721	V728A	728	Missense	distal	7	no	135.760	136.927	EPSD	COSMIC	112.929	Up-regulation
CMGC_MAPK_p38_MAPK12_ST	P10636	MAPT	P53778	MAPK12	T731	G732S	732	Missense	proximal	1	no	114.564	60.457	EPSD	COSMIC	112.929	Loss
CMGC_MAPK_p38_MAPK12_ST	P10636	MAPT	P53778	MAPK12	T731	D735N	735	Missense	distal	4	no	114.564	113.971	EPSD	COSMIC	112.929	Down-regulation
CMGC_MAPK_p38_MAPK12_ST	P10636	MAPT	P53778	MAPK12	T731	G732C	732	Missense	proximal	1	no	114.564	-59.283	EPSD	COSMIC	112.929	Loss
CMGC_MAPK_p38_MAPK12_ST	P10636	MAPT	P53778	MAPK12	T731	V728M	728	Missense	distal	-3	no	114.564	114.827	EPSD	COSMIC	112.929	Up-regulation
CMGC_MAPK_p38_MAPK12_ST	P10636	MAPT	P53778	MAPK12	T731	V728A	728	Missense	distal	-3	no	114.564	115.127	EPSD	COSMIC	112.929	Up-regulation
CMGC_MAPK_p38_MAPK12_ST	P10636	MAPT	P53778	MAPK12	S739	G732S	732	Missense	distal	-7	no	131.198	129.996	EPSD	COSMIC	112.929	Down-regulation
CMGC_MAPK_p38_MAPK12_ST	P10636	MAPT	P53778	MAPK12	S739	D735N	735	Missense	distal	-4	no	131.198	124.176	EPSD	COSMIC	112.929	Down-regulation
CMGC_MAPK_p38_MAPK12_ST	P10636	MAPT	P53778	MAPK12	S739	G732C	732	Missense	distal	-7	no	131.198	131.928	EPSD	COSMIC	112.929	Up-regulation
CMGC_MAPK_p38_MAPK12_ST	P10636	MAPT	P53778	MAPK12	S739	T744M	744	Missense	distal	5	no	131.198	130.677	EPSD	COSMIC	112.929	Down-regulation
CMGC_MAPK_p38_MAPK12_ST	P10636	MAPT	P53778	MAPK12	S739	A743T	743	Missense	distal	4	no	131.198	130.469	EPSD	COSMIC	112.929	Down-regulation
CMGC_MAPK_p38_MAPK12_ST	P10636	MAPT	P53778	MAPK12	T744	E748K	748	Missense	distal	4	no	114.728	115.499	EPSD	COSMIC	112.929	Up-regulation
CMGC_MAPK_p38_MAPK12_ST	P10636	MAPT	P53778	MAPK12	T744	T744M	744	Missense	central	0	yes	114.728	0.000	EPSD	COSMIC	112.929	Loss
CMGC_MAPK_p38_MAPK12_ST	P10636	MAPT	P53778	MAPK12	T744	A743T	743	Missense	proximal	-1	no	114.728	114.535	EPSD	COSMIC	112.929	Down-regulation
CMGC_MAPK_p38_MAPK12_ST	P26045	PTPN3	P53778	MAPK12	S372	W379L	379	Missense	distal	7	no	127.394	126.837	EPSD	COSMIC	112.929	Down-regulation
CMGC_MAPK_p38_MAPK12_ST	P26045	PTPN3	P53778	MAPK12	S372	S372Y	372	Missense	central	0	yes	127.394	0.000	EPSD	COSMIC	112.929	Loss
CMGC_MAPK_p38_MAPK12_ST	P26045	PTPN3	P53778	MAPK12	S372	R371C	371	Missense	proximal	-1	no	127.394	126.210	EPSD	COSMIC	112.929	Down-regulation
CMGC_MAPK_p38_MAPK12_ST	P26045	PTPN3	P53778	MAPK12	T376	W379L	379	Missense	distal	3	no	131.251	130.803	EPSD	COSMIC	112.929	Down-regulation
CMGC_MAPK_p38_MAPK12_ST	P26045	PTPN3	P53778	MAPK12	T376	S372Y	372	Missense	distal	-4	no	131.251	127.997	EPSD	COSMIC	112.929	Down-regulation
CMGC_MAPK_p38_MAPK12_ST	P26045	PTPN3	P53778	MAPK12	T376	R371C	371	Missense	distal	-5	no	131.251	131.132	EPSD	COSMIC	112.929	Down-regulation
CMGC_MAPK_p38_MAPK12_ST	P26045	PTPN3	P53778	MAPK12	S381	W379L	379	Missense	proximal	-2	no	118.537	121.034	EPSD	COSMIC	112.929	Up-regulation
CMGC_MAPK_p38_MAPK12_ST	P26045	PTPN3	P53778	MAPK12	S434	V429M	429	Missense	distal	-5	no	126.560	126.585	EPSD	COSMIC	112.929	Up-regulation
CMGC_MAPK_p38_MAPK12_ST	P26045	PTPN3	P53778	MAPK12	S434	N432Y	432	Missense	proximal	-2	no	126.560	131.985	EPSD	COSMIC	112.929	Up-regulation
CMGC_MAPK_p38_MAPK12_ST	P26045	PTPN3	P53778	MAPK12	S434	N432S	432	Missense	proximal	-2	no	126.560	131.115	EPSD	COSMIC	112.929	Up-regulation
CMGC_MAPK_p38_MAPK12_ST	P26045	PTPN3	P53778	MAPK12	S434	E438Q	438	Missense	distal	4	no	126.560	126.569	EPSD	COSMIC	112.929	Up-regulation
CMGC_MAPK_p38_MAPK12_ST	P26045	PTPN3	P53778	MAPK12	S434	H436Y	436	Missense	proximal	2	no	126.560	127.324	EPSD	COSMIC;GDSC	112.929	Up-regulation
CMGC_MAPK_p38_MAPK12_ST	P26045	PTPN3	P53778	MAPK12	S434	S434I	434	Missense	central	0	yes	126.560	0.000	EPSD	COSMIC	112.929	Loss
CMGC_MAPK_p38_MAPK12_ST	P26045	PTPN3	P53778	MAPK12	S434	S430P	430	Missense	distal	-4	no	126.560	122.484	EPSD	COSMIC	112.929	Down-regulation
CMGC_MAPK_p38_MAPK12_ST	P26045	PTPN3	P53778	MAPK12	S469	S467N	467	Missense	proximal	-2	no	126.782	122.226	EPSD	COSMIC	112.929	Down-regulation
CMGC_MAPK_p38_MAPK12_ST	P26045	PTPN3	P53778	MAPK12	S469	V473I	473	Missense	distal	4	no	126.782	127.569	EPSD	COSMIC	112.929	Up-regulation
CMGC_MAPK_p38_MAPK12_ST	P26045	PTPN3	P53778	MAPK12	S544	R539S	539	Missense	distal	-5	no	126.321	126.571	EPSD	COSMIC	112.929	Up-regulation
CMGC_MAPK_p38_MAPK12_ST	P26045	PTPN3	P53778	MAPK12	S544	S538T	538	Missense	distal	-6	no	126.321	127.847	EPSD	COSMIC	112.929	Up-regulation
CMGC_MAPK_p38_MAPK12_ST	O43464	HTRA2	P53778	MAPK12	T54	V50G	50	Missense	distal	-4	no	121.041	129.544	EPSD	COSMIC	112.929	Up-regulation
CMGC_MAPK_p38_MAPK12_ST	O43464	HTRA2	P53778	MAPK12	T54	W58C	58	Missense	distal	4	no	121.041	120.298	EPSD	COSMIC	112.929	Down-regulation
CMGC_MAPK_p38_MAPK12_ST	O43464	HTRA2	P53778	MAPK12	S56	V50G	50	Missense	distal	-6	no	114.508	113.345	EPSD	COSMIC	112.929	Down-regulation
CMGC_MAPK_p38_MAPK12_ST	O43464	HTRA2	P53778	MAPK12	S56	W58C	58	Missense	proximal	2	no	114.508	114.032	EPSD	COSMIC	112.929	Down-regulation
CMGC_MAPK_p38_MAPK12_ST	O43464	HTRA2	P53778	MAPK12	S142	A141S	141	Missense	proximal	-1	no	134.654	135.592	PhosphoSitePlus	COSMIC	112.929	Up-regulation
CMGC_MAPK_p38_MAPK12_ST	O43464	HTRA2	P53778	MAPK12	S142	S137R	137	Missense	distal	-5	no	134.654	134.404	PhosphoSitePlus	COSMIC	112.929	Down-regulation
CMGC_MAPK_p38_MAPK12_ST	O43464	HTRA2	P53778	MAPK12	S142	P139Q	139	Missense	distal	-3	no	134.654	134.221	PhosphoSitePlus	COSMIC	112.929	Down-regulation
CMGC_MAPK_p38_MAPK12_ST	O43464	HTRA2	P53778	MAPK12	T453	T457K	457	Missense	distal	4	no	115.705	115.779	EPSD	COSMIC	112.929	Up-regulation
CMGC_MAPK_p38_MAPK12_ST	O43464	HTRA2	P53778	MAPK12	T453	Y451C	451	Missense	proximal	-2	no	115.705	105.558	EPSD	COSMIC	112.929	Loss
CMGC_MAPK_p38_MAPK12_ST	P07900	HSP90AA1	P53778	MAPK12	S63	K58T	58	Missense	distal	-5	no	115.703	115.663	EPSD	COSMIC	112.929	Down-regulation
CMGC_MAPK_p38_MAPK12_ST	P07900	HSP90AA1	P53778	MAPK12	S72	I78F	78	Missense	distal	6	no	126.628	125.291	EPSD	COSMIC	112.929	Down-regulation
CMGC_MAPK_p38_MAPK12_ST	P07900	HSP90AA1	P53778	MAPK12	S315	D319G	319	Missense	distal	4	no	114.144	113.960	EPSD	COSMIC	112.929	Down-regulation
CMGC_MAPK_p38_MAPK12_ST	P07900	HSP90AA1	P53778	MAPK12	S315	E321D	321	Missense	distal	6	no	114.144	115.246	EPSD	COSMIC	112.929	Up-regulation
CMGC_MAPK_p38_MAPK12_ST	P07900	HSP90AA1	P53778	MAPK12	S470	S470C	470	Missense	central	0	yes	114.747	0.000	EPSD	COSMIC;CCLE	112.929	Loss
CMGC_MAPK_p38_MAPK12_ST	P07900	HSP90AA1	P53778	MAPK12	S470	G471V	471	Missense	proximal	1	no	114.747	53.076	EPSD	COSMIC	112.929	Loss
CMGC_MAPK_p38_MAPK12_ST	P07900	HSP90AA1	P53778	MAPK12	S470	D472N	472	Missense	proximal	2	no	114.747	114.457	EPSD	COSMIC	112.929	Down-regulation
CMGC_MAPK_p38_MAPK12_ST	P07900	HSP90AA1	P53778	MAPK12	S476	S470C	470	Missense	distal	-6	no	110.298	113.421	EPSD	COSMIC;CCLE	112.929	Gain
CMGC_MAPK_p38_MAPK12_ST	P07900	HSP90AA1	P53778	MAPK12	T495	T495R	495	Missense	central	0	yes	117.784	0.000	EPSD	COSMIC	112.929	Loss
CMGC_MAPK_p38_MAPK12_ST	P07900	HSP90AA1	P53778	MAPK12	T645	I643F	643	Missense	proximal	-2	no	114.013	102.235	EPSD	COSMIC	112.929	Loss
CMGC_MAPK_p38_MAPK12_ST	P07900	HSP90AA1	P53778	MAPK12	T645	I643T	643	Missense	proximal	-2	no	114.013	110.085	EPSD	COSMIC	112.929	Loss
CMGC_MAPK_p38_MAPK12_ST	P30281	CCND3	P53778	MAPK12	S133	P134A	134	Missense	proximal	1	no	123.799	38.655	EPSD	COSMIC	112.929	Loss
CMGC_MAPK_p38_MAPK12_ST	P30281	CCND3	P53778	MAPK12	S133	A131V	131	Missense	proximal	-2	no	123.799	119.831	EPSD	COSMIC	112.929	Down-regulation
CMGC_MAPK_p38_MAPK12_ST	P30281	CCND3	P53778	MAPK12	S133	L137V	137	Missense	distal	4	no	123.799	123.730	EPSD	COSMIC	112.929	Down-regulation
CMGC_MAPK_p38_MAPK12_ST	P30281	CCND3	P53778	MAPK12	S133	S133L	133	Missense	central	0	yes	123.799	0.000	EPSD	COSMIC	112.929	Loss
CMGC_MAPK_p38_MAPK12_ST	P30281	CCND3	P53778	MAPK12	S264	K268E	268	Missense	distal	4	no	126.610	125.840	EPSD	COSMIC	112.929	Down-regulation
CMGC_MAPK_p38_MAPK12_ST	P30281	CCND3	P53778	MAPK12	S264	P267L	267	Missense	distal	3	no	126.610	125.816	EPSD	COSMIC	112.929	Down-regulation
CMGC_MAPK_p38_MAPK12_ST	P30281	CCND3	P53778	MAPK12	T283	P284S	284	Missense	proximal	1	no	130.221	59.735	PhosphoSitePlus	COSMIC;CCLE	112.929	Loss
CMGC_MAPK_p38_MAPK12_ST	P30281	CCND3	P53778	MAPK12	T283	P284L	284	Missense	proximal	1	no	130.221	113.476	PhosphoSitePlus	COSMIC;CCLE	112.929	Down-regulation
CMGC_MAPK_p38_MAPK12_ST	P30281	CCND3	P53778	MAPK12	T283	I290R	290	Missense	distal	7	no	130.221	129.060	PhosphoSitePlus	COSMIC;CCLE	112.929	Down-regulation
CMGC_MAPK_p38_MAPK12_ST	P30281	CCND3	P53778	MAPK12	T283	T283I	283	Missense	central	0	yes	130.221	0.000	PhosphoSitePlus	COSMIC;GDSC;CCLE	112.929	Loss
CMGC_MAPK_p38_MAPK12_ST	P30281	CCND3	P53778	MAPK12	T283	V287G	287	Missense	distal	4	no	130.221	131.185	PhosphoSitePlus	COSMIC	112.929	Up-regulation
CMGC_MAPK_p38_MAPK12_ST	P30281	CCND3	P53778	MAPK12	T283	P284R	284	Missense	proximal	1	no	130.221	-55.523	PhosphoSitePlus	COSMIC	112.929	Loss
CMGC_MAPK_p38_MAPK12_ST	P30281	CCND3	P53778	MAPK12	T283	D286G	286	Missense	distal	3	no	130.221	129.351	PhosphoSitePlus	COSMIC	112.929	Down-regulation
CMGC_MAPK_p38_MAPK12_ST	P30281	CCND3	P53778	MAPK12	T283	V287D	287	Missense	distal	4	no	130.221	131.368	PhosphoSitePlus	COSMIC;CCLE	112.929	Up-regulation
CMGC_MAPK_p38_MAPK12_ST	P30281	CCND3	P53778	MAPK12	T283	P284T	284	Missense	proximal	1	no	130.221	-0.991	PhosphoSitePlus	COSMIC	112.929	Loss
CMGC_MAPK_p38_MAPK12_ST	P30281	CCND3	P53778	MAPK12	T283	G277W	277	Missense	distal	-6	no	130.221	130.917	PhosphoSitePlus	COSMIC	112.929	Up-regulation
CMGC_MAPK_p38_MAPK12_ST	P30281	CCND3	P53778	MAPK12	T283	A289P	289	Missense	distal	6	no	130.221	130.054	PhosphoSitePlus	COSMIC	112.929	Down-regulation
CMGC_MAPK_p38_MAPK12_ST	P30281	CCND3	P53778	MAPK12	T288	A289P	289	Missense	proximal	1	no	38.225	123.370	EPSD	COSMIC	112.929	Gain
STE_STE7_MEK4_MAP2K4_ST	P53779	MAPK10	P45985	MAP2K4	T281	E285D	285	Missense	distal	4	no	0.006	0.007	EPSD	COSMIC	0.006	Up-regulation
STE_STE7_MEK4_MAP2K4_ST	P53779	MAPK10	P45985	MAP2K4	T281	P284L	284	Missense	distal	3	no	0.006	0.008	EPSD	COSMIC	0.006	Up-regulation
STE_STE7_MEK4_MAP2K4_ST	P45983	MAPK8	P45985	MAP2K4	T183	G177K	177	Missense	distal	-6	no	0.031	0.032	PhosphoSitePlus;EPSD	COSMIC	0.006	Up-regulation
STE_STE7_MEK4_MAP2K4_ST	P45983	MAPK8	P45985	MAP2K4	T183	T183A	183	Missense	central	0	yes	0.031	0.000	PhosphoSitePlus;EPSD	COSMIC	0.006	Loss
STE_STE7_MEK4_MAP2K4_ST	P45983	MAPK8	P45985	MAP2K4	S377	G380V	380	Missense	distal	3	no	0.002	0.007	EPSD;PhosphoSitePlus	COSMIC	0.006	Gain
STE_STE7_MEK4_MAP2K4_ST	P45984	MAPK9	P45985	MAP2K4	T183	R189W	189	Missense	distal	6	no	0.031	0.032	EPSD	COSMIC	0.006	Up-regulation
STE_STE7_MEK4_MAP2K4_ST	P45984	MAPK9	P45985	MAP2K4	T183	R189Q	189	Missense	distal	6	no	0.031	0.032	EPSD	COSMIC	0.006	Up-regulation
STE_STE7_MEK4_MAP2K4_ST	P19793	RXRA	P45985	MAP2K4	T82	G86C	86	Missense	distal	4	no	0.006	0.005	EPSD	COSMIC	0.006	Loss
STE_STE7_MEK4_MAP2K4_ST	P45985	MAP2K4	P45985	MAP2K4	S90	W95C	95	Missense	distal	5	no	0.006	0.007	EPSD	COSMIC	0.006	Up-regulation
STE_STE7_MEK4_MAP2K4_ST	P45985	MAP2K4	P45985	MAP2K4	S90	E92A	92	Missense	proximal	2	no	0.006	0.007	EPSD	COSMIC	0.006	Up-regulation
STE_STE7_MEK4_MAP2K4_ST	P45985	MAP2K4	P45985	MAP2K4	S90	G85R	85	Missense	distal	-5	no	0.006	0.007	EPSD	COSMIC	0.006	Up-regulation
STE_STE7_MEK4_MAP2K4_ST	P45985	MAP2K4	P45985	MAP2K4	S257	T261R	261	Missense	distal	4	no	0.019	0.020	PhosphoSitePlus;EPSD	COSMIC	0.006	Up-regulation
STE_STE7_MEK4_MAP2K4_ST	P45985	MAP2K4	P45985	MAP2K4	S257	S257C	257	Missense	central	0	yes	0.019	0.000	PhosphoSitePlus;EPSD	COSMIC	0.006	Loss
STE_STE7_MEK4_MAP2K4_ST	P45985	MAP2K4	P45985	MAP2K4	S257	D263Y	263	Missense	distal	6	no	0.019	0.020	PhosphoSitePlus;EPSD	COSMIC	0.006	Up-regulation
STE_STE7_MEK4_MAP2K4_ST	P45985	MAP2K4	P45985	MAP2K4	S257	S257Y	257	Missense	central	0	yes	0.019	0.000	PhosphoSitePlus;EPSD	COSMIC	0.006	Loss
STE_STE7_MEK4_MAP2K4_ST	P45985	MAP2K4	P45985	MAP2K4	T261	T261R	261	Missense	central	0	yes	0.013	0.000	EPSD;PhosphoSitePlus	COSMIC	0.006	Loss
STE_STE7_MEK4_MAP2K4_ST	P45985	MAP2K4	P45985	MAP2K4	T261	D263Y	263	Missense	proximal	2	no	0.013	0.014	EPSD;PhosphoSitePlus	COSMIC	0.006	Up-regulation
STE_STE7_MEK4_MAP2K4_ST	P45985	MAP2K4	P45985	MAP2K4	T302	F305I	305	Missense	distal	3	no	0.004	0.006	EPSD	COSMIC	0.006	Gain
AGC_PDK1_PDPK1_ST	Q9HBY8	SGK2	O15530	PDPK1	S64	G67R	67	Missense	distal	3	no	6.464	6.162	EPSD	COSMIC	3.516	Down-regulation
AGC_PDK1_PDPK1_ST	Q9HBY8	SGK2	O15530	PDPK1	S64	G67W	67	Missense	distal	3	no	6.464	6.057	EPSD	COSMIC	3.516	Down-regulation
AGC_PDK1_PDPK1_ST	Q9HBY8	SGK2	O15530	PDPK1	S64	P71S	71	Missense	distal	7	no	6.464	6.303	EPSD	COSMIC	3.516	Down-regulation
AGC_PDK1_PDPK1_ST	Q9HBY8	SGK2	O15530	PDPK1	S70	G67R	67	Missense	distal	-3	no	4.284	5.024	EPSD	COSMIC	3.516	Up-regulation
AGC_PDK1_PDPK1_ST	Q9HBY8	SGK2	O15530	PDPK1	S70	G67W	67	Missense	distal	-3	no	4.284	4.262	EPSD	COSMIC	3.516	Down-regulation
AGC_PDK1_PDPK1_ST	Q9HBY8	SGK2	O15530	PDPK1	S70	R75S	75	Missense	distal	5	no	4.284	4.815	EPSD	COSMIC	3.516	Up-regulation
AGC_PDK1_PDPK1_ST	Q9HBY8	SGK2	O15530	PDPK1	S70	P71S	71	Missense	proximal	1	no	4.284	1.489	EPSD	COSMIC	3.516	Loss
AGC_PDK1_PDPK1_ST	Q9HBY8	SGK2	O15530	PDPK1	T253	C255F	255	Missense	proximal	2	no	10.865	10.798	PhosphoSitePlus	COSMIC	3.516	Down-regulation
AGC_PDK1_PDPK1_ST	Q9HBY8	SGK2	O15530	PDPK1	T253	T253A	253	Missense	central	0	yes	10.865	0.000	PhosphoSitePlus	COSMIC	3.516	Loss
AGC_PDK1_PDPK1_ST	Q9HBY8	SGK2	O15530	PDPK1	T253	Y260H	260	Missense	distal	7	no	10.865	10.823	PhosphoSitePlus	COSMIC	3.516	Down-regulation
AGC_PDK1_PDPK1_ST	Q9HBY8	SGK2	O15530	PDPK1	T253	S252F	252	Missense	proximal	-1	no	10.865	10.256	PhosphoSitePlus	COSMIC	3.516	Down-regulation
AGC_PDK1_PDPK1_ST	Q9HBY8	SGK2	O15530	PDPK1	T253	T257I	257	Missense	distal	4	no	10.865	9.509	PhosphoSitePlus	COSMIC	3.516	Down-regulation
AGC_PDK1_PDPK1_ST	Q9HBY8	SGK2	O15530	PDPK1	T253	P258L	258	Missense	distal	5	no	10.865	9.870	PhosphoSitePlus	COSMIC	3.516	Down-regulation
AGC_PDK1_PDPK1_ST	O15530	PDPK1	O15530	PDPK1	S92	L88V	88	Missense	distal	-4	no	5.413	5.363	EPSD	COSMIC	3.516	Down-regulation
AGC_PDK1_PDPK1_ST	O15530	PDPK1	O15530	PDPK1	T95	L88V	88	Missense	distal	-7	no	3.238	3.774	EPSD	COSMIC	3.516	Gain
AGC_PDK1_PDPK1_ST	O15530	PDPK1	O15530	PDPK1	S241	Y248H	248	Missense	distal	7	no	7.710	7.668	EPSD;PhosphoSitePlus	COSMIC	3.516	Down-regulation
AGC_PDK1_PDPK1_ST	O15530	PDPK1	O15530	PDPK1	S250	Y248H	248	Missense	proximal	-2	no	5.053	5.121	EPSD	COSMIC	3.516	Up-regulation
AGC_PDK1_PDPK1_ST	O15530	PDPK1	O15530	PDPK1	T354	L350F	350	Missense	distal	-4	no	6.128	6.223	EPSD	COSMIC	3.516	Up-regulation
AGC_PDK1_PDPK1_ST	O15530	PDPK1	O15530	PDPK1	S393	S396F	396	Missense	distal	3	no	5.190	4.595	PhosphoSitePlus;EPSD	COSMIC	3.516	Down-regulation
AGC_PDK1_PDPK1_ST	O15530	PDPK1	O15530	PDPK1	S393	S398L	398	Missense	distal	5	no	5.190	4.083	PhosphoSitePlus;EPSD	COSMIC	3.516	Down-regulation
AGC_PDK1_PDPK1_ST	O15530	PDPK1	O15530	PDPK1	S393	Q387R	387	Missense	distal	-6	no	5.190	5.180	PhosphoSitePlus;EPSD	COSMIC	3.516	Down-regulation
AGC_PDK1_PDPK1_ST	O15530	PDPK1	O15530	PDPK1	S393	S394L	394	Missense	proximal	1	no	5.190	5.565	PhosphoSitePlus;EPSD	COSMIC	3.516	Up-regulation
AGC_PDK1_PDPK1_ST	O15530	PDPK1	O15530	PDPK1	S393	Q387H	387	Missense	distal	-6	no	5.190	5.188	PhosphoSitePlus;EPSD	COSMIC;CCLE	3.516	Down-regulation
AGC_PDK1_PDPK1_ST	O15530	PDPK1	O15530	PDPK1	S396	S396F	396	Missense	central	0	yes	5.565	0.000	EPSD;PhosphoSitePlus	COSMIC	3.516	Loss
AGC_PDK1_PDPK1_ST	O15530	PDPK1	O15530	PDPK1	S396	G403W	403	Missense	distal	7	no	5.565	5.729	EPSD;PhosphoSitePlus	COSMIC	3.516	Up-regulation
AGC_PDK1_PDPK1_ST	O15530	PDPK1	O15530	PDPK1	S396	G403E	403	Missense	distal	7	no	5.565	5.645	EPSD;PhosphoSitePlus	COSMIC	3.516	Up-regulation
AGC_PDK1_PDPK1_ST	O15530	PDPK1	O15530	PDPK1	S396	S398L	398	Missense	proximal	2	no	5.565	5.480	EPSD;PhosphoSitePlus	COSMIC	3.516	Down-regulation
AGC_PDK1_PDPK1_ST	O15530	PDPK1	O15530	PDPK1	S396	G403S	403	Missense	distal	7	no	5.565	6.038	EPSD;PhosphoSitePlus	COSMIC	3.516	Up-regulation
AGC_PDK1_PDPK1_ST	O15530	PDPK1	O15530	PDPK1	S396	S394L	394	Missense	proximal	-2	no	5.565	5.392	EPSD;PhosphoSitePlus	COSMIC	3.516	Down-regulation
AGC_PDK1_PDPK1_ST	O15530	PDPK1	O15530	PDPK1	S410	G403W	403	Missense	distal	-7	no	4.858	3.887	EPSD;PhosphoSitePlus	COSMIC	3.516	Down-regulation
AGC_PDK1_PDPK1_ST	O15530	PDPK1	O15530	PDPK1	S410	G403E	403	Missense	distal	-7	no	4.858	4.202	EPSD;PhosphoSitePlus	COSMIC	3.516	Down-regulation
AGC_PDK1_PDPK1_ST	O15530	PDPK1	O15530	PDPK1	S410	G403S	403	Missense	distal	-7	no	4.858	4.876	EPSD;PhosphoSitePlus	COSMIC	3.516	Up-regulation
AGC_PDK1_PDPK1_ST	O15530	PDPK1	O15530	PDPK1	T513	E507Q	507	Missense	distal	-6	no	5.407	5.385	EPSD;PhosphoSitePlus	COSMIC	3.516	Down-regulation
AGC_PDK1_PDPK1_ST	O15530	PDPK1	O15530	PDPK1	T513	T518M	518	Missense	distal	5	no	5.407	5.152	EPSD;PhosphoSitePlus	COSMIC	3.516	Down-regulation
AGC_PDK1_PDPK1_ST	O15530	PDPK1	O15530	PDPK1	T513	N520K	520	Missense	distal	7	no	5.407	5.020	EPSD;PhosphoSitePlus	COSMIC	3.516	Down-regulation
AGC_PDK1_PDPK1_ST	O15530	PDPK1	O15530	PDPK1	T513	T518S	518	Missense	distal	5	no	5.407	5.360	EPSD;PhosphoSitePlus	COSMIC	3.516	Down-regulation
AGC_PDK1_PDPK1_ST	Q16512	PKN1	O15530	PDPK1	S112	A115V	115	Missense	distal	3	no	4.232	4.096	EPSD	COSMIC	3.516	Down-regulation
AGC_PDK1_PDPK1_ST	Q16512	PKN1	O15530	PDPK1	S112	Q111H	111	Missense	proximal	-1	no	4.232	4.327	EPSD	COSMIC	3.516	Up-regulation
AGC_PDK1_PDPK1_ST	Q16512	PKN1	O15530	PDPK1	S205	A198V	198	Missense	distal	-7	no	4.302	4.291	EPSD	COSMIC	3.516	Down-regulation
AGC_PDK1_PDPK1_ST	Q16512	PKN1	O15530	PDPK1	T353	D355N	355	Missense	proximal	2	no	6.038	6.089	EPSD	COSMIC	3.516	Up-regulation
AGC_PDK1_PDPK1_ST	Q16512	PKN1	O15530	PDPK1	T353	P354L	354	Missense	proximal	1	no	6.038	3.619	EPSD	COSMIC	3.516	Down-regulation
AGC_PDK1_PDPK1_ST	Q16512	PKN1	O15530	PDPK1	S374	R378Q	378	Missense	distal	4	no	5.526	5.025	EPSD	COSMIC	3.516	Down-regulation
AGC_PDK1_PDPK1_ST	Q16512	PKN1	O15530	PDPK1	S533	T527M	527	Missense	distal	-6	no	4.154	4.147	EPSD	COSMIC	3.516	Down-regulation
AGC_PDK1_PDPK1_ST	Q16512	PKN1	O15530	PDPK1	S533	S540F	540	Missense	distal	7	no	4.154	3.868	EPSD	COSMIC;CCLE	3.516	Down-regulation
AGC_PDK1_PDPK1_ST	Q16512	PKN1	O15530	PDPK1	S537	S540F	540	Missense	distal	3	no	4.668	4.074	EPSD	COSMIC;CCLE	3.516	Down-regulation
AGC_PDK1_PDPK1_ST	Q16512	PKN1	O15530	PDPK1	S562	D569N	569	Missense	distal	7	no	4.751	5.098	EPSD	COSMIC	3.516	Up-regulation
AGC_PDK1_PDPK1_ST	Q16512	PKN1	O15530	PDPK1	S566	D569N	569	Missense	distal	3	no	3.532	3.576	EPSD	COSMIC	3.516	Up-regulation
AGC_PDK1_PDPK1_ST	Q16512	PKN1	O15530	PDPK1	S566	S572F	572	Missense	distal	6	no	3.532	3.534	EPSD	COSMIC	3.516	Up-regulation
AGC_PDK1_PDPK1_ST	Q16512	PKN1	O15530	PDPK1	S566	S573N	573	Missense	distal	7	no	3.532	3.485	EPSD	COSMIC	3.516	Loss
AGC_PDK1_PDPK1_ST	Q16512	PKN1	O15530	PDPK1	S573	S576N	576	Missense	distal	3	no	7.194	7.117	EPSD	COSMIC	3.516	Down-regulation
AGC_PDK1_PDPK1_ST	Q16512	PKN1	O15530	PDPK1	S573	D569N	569	Missense	distal	-4	no	7.194	7.152	EPSD	COSMIC	3.516	Down-regulation
AGC_PDK1_PDPK1_ST	Q16512	PKN1	O15530	PDPK1	S573	S572F	572	Missense	proximal	-1	no	7.194	6.586	EPSD	COSMIC	3.516	Down-regulation
AGC_PDK1_PDPK1_ST	Q16512	PKN1	O15530	PDPK1	S573	S573N	573	Missense	central	0	yes	7.194	0.000	EPSD	COSMIC	3.516	Loss
AGC_PDK1_PDPK1_ST	Q16512	PKN1	O15530	PDPK1	S573	S578F	578	Missense	distal	5	no	7.194	5.779	EPSD	COSMIC	3.516	Down-regulation
AGC_PDK1_PDPK1_ST	Q16512	PKN1	O15530	PDPK1	S575	S576N	576	Missense	proximal	1	no	4.264	4.601	EPSD	COSMIC	3.516	Up-regulation
AGC_PDK1_PDPK1_ST	Q16512	PKN1	O15530	PDPK1	S575	D569N	569	Missense	distal	-6	no	4.264	4.211	EPSD	COSMIC	3.516	Down-regulation
AGC_PDK1_PDPK1_ST	Q16512	PKN1	O15530	PDPK1	S575	S572F	572	Missense	distal	-3	no	4.264	2.795	EPSD	COSMIC	3.516	Loss
AGC_PDK1_PDPK1_ST	Q16512	PKN1	O15530	PDPK1	S575	S573N	573	Missense	proximal	-2	no	4.264	4.200	EPSD	COSMIC	3.516	Down-regulation
AGC_PDK1_PDPK1_ST	Q16512	PKN1	O15530	PDPK1	S575	S578F	578	Missense	distal	3	no	4.264	3.669	EPSD	COSMIC	3.516	Down-regulation
AGC_PDK1_PDPK1_ST	Q16512	PKN1	O15530	PDPK1	S575	S579N	579	Missense	distal	4	no	4.264	3.659	EPSD	COSMIC	3.516	Down-regulation
AGC_PDK1_PDPK1_ST	Q16512	PKN1	O15530	PDPK1	S579	S576N	576	Missense	distal	-3	no	5.212	4.630	EPSD	COSMIC	3.516	Down-regulation
AGC_PDK1_PDPK1_ST	Q16512	PKN1	O15530	PDPK1	S579	S572F	572	Missense	distal	-7	no	5.212	3.691	EPSD	COSMIC	3.516	Down-regulation
AGC_PDK1_PDPK1_ST	Q16512	PKN1	O15530	PDPK1	S579	S573N	573	Missense	distal	-6	no	5.212	5.206	EPSD	COSMIC	3.516	Down-regulation
AGC_PDK1_PDPK1_ST	Q16512	PKN1	O15530	PDPK1	S579	S578F	578	Missense	proximal	-1	no	5.212	4.603	EPSD	COSMIC	3.516	Down-regulation
AGC_PDK1_PDPK1_ST	Q16512	PKN1	O15530	PDPK1	S579	S579N	579	Missense	central	0	yes	5.212	0.000	EPSD	COSMIC	3.516	Loss
AGC_PDK1_PDPK1_ST	Q16512	PKN1	O15530	PDPK1	T596	A600T	600	Missense	distal	4	no	5.235	5.724	EPSD	COSMIC	3.516	Up-regulation
AGC_PDK1_PDPK1_ST	Q16512	PKN1	O15530	PDPK1	T596	Q594H	594	Missense	proximal	-2	no	5.235	5.266	EPSD	COSMIC	3.516	Up-regulation
AGC_PDK1_PDPK1_ST	Q16512	PKN1	O15530	PDPK1	S603	A600T	600	Missense	distal	-3	no	2.954	3.539	EPSD	COSMIC	3.516	Gain
AGC_PDK1_PDPK1_ST	Q16512	PKN1	O15530	PDPK1	S773	G767R	767	Missense	distal	-6	no	4.118	4.155	PhosphoSitePlus;EPSD	COSMIC	3.516	Up-regulation
AGC_PDK1_PDPK1_ST	Q16512	PKN1	O15530	PDPK1	T774	G767R	767	Missense	distal	-7	no	10.248	10.051	EPSD;PhosphoSitePlus	COSMIC	3.516	Down-regulation
AGC_PDK1_PDPK1_ST	Q16512	PKN1	O15530	PDPK1	S791	T793M	793	Missense	proximal	2	no	4.656	4.698	EPSD	COSMIC	3.516	Up-regulation
AGC_PDK1_PDPK1_ST	Q16512	PKN1	O15530	PDPK1	S791	T788M	788	Missense	distal	-3	no	4.656	4.508	EPSD	COSMIC	3.516	Down-regulation
AGC_PDK1_PDPK1_ST	Q16512	PKN1	O15530	PDPK1	S916	A921V	921	Missense	distal	5	no	5.868	5.651	EPSD	COSMIC;CCLE	3.516	Down-regulation
AGC_PDK1_PDPK1_ST	Q99814	EPAS1	O15530	PDPK1	T324	G323E	323	Missense	proximal	-1	no	5.953	5.788	PhosphoSitePlus	COSMIC	3.516	Down-regulation
AGC_PDK1_PDPK1_ST	Q99814	EPAS1	O15530	PDPK1	T324	T321I	321	Missense	distal	-3	no	5.953	4.673	PhosphoSitePlus	COSMIC	3.516	Down-regulation
AGC_PDK1_PDPK1_ST	Q99814	EPAS1	O15530	PDPK1	S672	S672Y	672	Missense	central	0	yes	7.070	0.000	EPSD	COSMIC;GDSC;CCLE	3.516	Loss
AGC_PDK1_PDPK1_ST	Q99814	EPAS1	O15530	PDPK1	S677	S672Y	672	Missense	distal	-5	no	4.508	4.717	EPSD	COSMIC;GDSC;CCLE	3.516	Up-regulation
AGC_PDK1_PDPK1_ST	Q99814	EPAS1	O15530	PDPK1	T678	S672Y	672	Missense	distal	-6	no	4.790	4.848	EPSD	COSMIC;GDSC;CCLE	3.516	Up-regulation
AGC_PDK1_PDPK1_ST	Q99814	EPAS1	O15530	PDPK1	S696	A698T	698	Missense	proximal	2	no	3.601	3.631	EPSD	COSMIC	3.516	Up-regulation
AGC_PDK1_PDPK1_ST	Q99814	EPAS1	O15530	PDPK1	S830	F831V	831	Missense	proximal	1	no	5.177	2.811	EPSD	COSMIC	3.516	Loss
AGC_PDK1_PDPK1_ST	Q99814	EPAS1	O15530	PDPK1	S830	R825P	825	Missense	distal	-5	no	5.177	5.134	EPSD	COSMIC	3.516	Down-regulation
AGC_PDK1_PDPK1_ST	P08559	PDHA1	O15530	PDPK1	S152	S152L	152	Missense	central	0	yes	3.613	0.000	EPSD	COSMIC	3.516	Loss
AGC_PDK1_PDPK1_ST	P08559	PDHA1	O15530	PDPK1	S152	M155V	155	Missense	distal	3	no	3.613	3.474	EPSD	COSMIC	3.516	Loss
AGC_PDK1_PDPK1_ST	P08559	PDHA1	O15530	PDPK1	S152	A146S	146	Missense	distal	-6	no	3.613	3.597	EPSD	COSMIC	3.516	Down-regulation
AGC_PDK1_PDPK1_ST	P08559	PDHA1	O15530	PDPK1	T231	S232F	232	Missense	proximal	1	no	0.946	4.283	EPSD	COSMIC	3.516	Gain
AGC_PDK1_PDPK1_ST	P08559	PDHA1	O15530	PDPK1	S232	S239F	239	Missense	distal	7	no	4.854	4.568	EPSD;PhosphoSitePlus	COSMIC	3.516	Down-regulation
AGC_PDK1_PDPK1_ST	P08559	PDHA1	O15530	PDPK1	S232	T231M	231	Missense	proximal	-1	no	4.854	4.896	EPSD;PhosphoSitePlus	COSMIC	3.516	Up-regulation
AGC_PDK1_PDPK1_ST	P08559	PDHA1	O15530	PDPK1	S232	R226H	226	Missense	distal	-6	no	4.854	4.862	EPSD;PhosphoSitePlus	COSMIC	3.516	Up-regulation
AGC_PDK1_PDPK1_ST	P08559	PDHA1	O15530	PDPK1	S232	S232F	232	Missense	central	0	yes	4.854	0.000	EPSD;PhosphoSitePlus	COSMIC	3.516	Loss
AGC_PDK1_PDPK1_ST	P08559	PDHA1	O15530	PDPK1	S232	E234K	234	Missense	proximal	2	no	4.854	4.834	EPSD;PhosphoSitePlus	COSMIC	3.516	Down-regulation
AGC_PDK1_PDPK1_ST	P08559	PDHA1	O15530	PDPK1	T286	Y287H	287	Missense	proximal	1	no	4.364	1.025	EPSD	COSMIC	3.516	Loss
AGC_PDK1_PDPK1_ST	P08559	PDHA1	O15530	PDPK1	T286	I280N	280	Missense	distal	-6	no	4.364	4.235	EPSD	COSMIC	3.516	Down-regulation
AGC_PDK1_PDPK1_ST	P08559	PDHA1	O15530	PDPK1	T286	M282L	282	Missense	distal	-4	no	4.364	4.483	EPSD	COSMIC	3.516	Up-regulation
AGC_PDK1_PDPK1_ST	P08559	PDHA1	O15530	PDPK1	T286	R288C	288	Missense	proximal	2	no	4.364	4.290	EPSD	COSMIC	3.516	Down-regulation
AGC_PDK1_PDPK1_ST	P08559	PDHA1	O15530	PDPK1	S293	Y287H	287	Missense	distal	-6	no	5.574	5.534	PhosphoSitePlus;EPSD	COSMIC	3.516	Down-regulation
AGC_PDK1_PDPK1_ST	P08559	PDHA1	O15530	PDPK1	S293	R288C	288	Missense	distal	-5	no	5.574	5.700	PhosphoSitePlus;EPSD	COSMIC	3.516	Up-regulation
AGC_PDK1_PDPK1_ST	P08559	PDHA1	O15530	PDPK1	S300	R302S	302	Missense	proximal	2	no	5.245	5.260	EPSD;PhosphoSitePlus	COSMIC	3.516	Up-regulation
AGC_PDK1_PDPK1_ST	P08559	PDHA1	O15530	PDPK1	S300	R304Q	304	Missense	distal	4	no	5.245	4.743	EPSD;PhosphoSitePlus	COSMIC;GDSC;CCLE	3.516	Down-regulation
AGC_PDK1_PDPK1_ST	P08559	PDHA1	O15530	PDPK1	S300	R302C	302	Missense	proximal	2	no	5.245	5.171	EPSD;PhosphoSitePlus	COSMIC	3.516	Down-regulation
AGC_PDK1_PDPK1_ST	P08559	PDHA1	O15530	PDPK1	S300	R302L	302	Missense	proximal	2	no	5.245	5.175	EPSD;PhosphoSitePlus	COSMIC	3.516	Down-regulation
AGC_PDK1_PDPK1_ST	P31751	AKT2	O15530	PDPK1	T72	R76H	76	Missense	distal	4	no	5.529	5.221	EPSD	COSMIC	3.516	Down-regulation
AGC_PDK1_PDPK1_ST	P31751	AKT2	O15530	PDPK1	T72	T72I	72	Missense	central	0	yes	5.529	0.000	EPSD	COSMIC	3.516	Loss
AGC_PDK1_PDPK1_ST	P31751	AKT2	O15530	PDPK1	T72	P70L	70	Missense	proximal	-2	no	5.529	5.361	EPSD	COSMIC	3.516	Down-regulation
AGC_PDK1_PDPK1_ST	P31751	AKT2	O15530	PDPK1	T72	R69L	69	Missense	distal	-3	no	5.529	4.873	EPSD	COSMIC	3.516	Down-regulation
AGC_PDK1_PDPK1_ST	P31751	AKT2	O15530	PDPK1	T72	Q79K	79	Missense	distal	7	no	5.529	5.329	EPSD	COSMIC	3.516	Down-regulation
AGC_PDK1_PDPK1_ST	P31751	AKT2	O15530	PDPK1	T72	V74A	74	Missense	proximal	2	no	5.529	5.500	EPSD	COSMIC	3.516	Down-regulation
AGC_PDK1_PDPK1_ST	P31751	AKT2	O15530	PDPK1	S126	S131T	131	Missense	distal	5	no	6.928	6.974	EPSD	COSMIC	3.516	Up-regulation
AGC_PDK1_PDPK1_ST	P31751	AKT2	O15530	PDPK1	S126	M120R	120	Missense	distal	-6	no	6.928	6.951	EPSD	COSMIC	3.516	Up-regulation
AGC_PDK1_PDPK1_ST	P31751	AKT2	O15530	PDPK1	S126	S130F	130	Missense	distal	4	no	6.928	5.398	EPSD	COSMIC	3.516	Down-regulation
AGC_PDK1_PDPK1_ST	P31751	AKT2	O15530	PDPK1	T309	S302C	302	Missense	distal	-7	no	10.762	9.823	PhosphoSitePlus	COSMIC	3.516	Down-regulation
AGC_PDK1_PDPK1_ST	P31751	AKT2	O15530	PDPK1	T451	D454N	454	Missense	distal	3	no	5.456	5.499	EPSD	COSMIC	3.516	Up-regulation
AGC_PDK1_PDPK1_ST	P31751	AKT2	O15530	PDPK1	T451	T444I	444	Missense	distal	-7	no	5.456	4.079	EPSD	COSMIC	3.516	Down-regulation
AGC_PDK1_PDPK1_ST	P31751	AKT2	O15530	PDPK1	T451	T449I	449	Missense	proximal	-2	no	5.456	5.214	EPSD	COSMIC	3.516	Down-regulation
AGC_PDK1_PDPK1_ST	P31751	AKT2	O15530	PDPK1	T451	D457N	457	Missense	distal	6	no	5.456	5.455	EPSD	COSMIC	3.516	Down-regulation
AGC_PDK1_PDPK1_ST	P31751	AKT2	O15530	PDPK1	S474	S478N	478	Missense	distal	4	no	3.538	2.933	EPSD	COSMIC	3.516	Loss
AGC_PDK1_PDPK1_ST	P31751	AKT2	O15530	PDPK1	S474	S474C	474	Missense	central	0	yes	3.538	0.000	EPSD	COSMIC	3.516	Loss
AGC_PDK1_PDPK1_ST	P31751	AKT2	O15530	PDPK1	S474	Y475C	475	Missense	proximal	1	no	3.538	-0.908	EPSD	COSMIC	3.516	Loss
AGC_PDK1_PDPK1_ST	P31751	AKT2	O15530	PDPK1	S474	R480H	480	Missense	distal	6	no	3.538	3.539	EPSD	COSMIC	3.516	Up-regulation
AGC_PDK1_PDPK1_ST	P31751	AKT2	O15530	PDPK1	S474	T468S	468	Missense	distal	-6	no	3.538	3.545	EPSD	COSMIC	3.516	Up-regulation
AGC_PDK1_PDPK1_ST	P05106	ITGB3	O15530	PDPK1	S110	R117W	117	Missense	distal	7	no	6.532	6.350	EPSD	COSMIC	3.516	Down-regulation
AGC_PDK1_PDPK1_ST	P05106	ITGB3	O15530	PDPK1	S110	R117Q	117	Missense	distal	7	no	6.532	6.424	EPSD	COSMIC	3.516	Down-regulation
AGC_PDK1_PDPK1_ST	P05106	ITGB3	O15530	PDPK1	S619	I615M	615	Missense	distal	-4	no	4.333	4.152	EPSD	COSMIC	3.516	Down-regulation
AGC_PDK1_PDPK1_ST	P05106	ITGB3	O15530	PDPK1	T779	A776V	776	Missense	distal	-3	no	4.971	5.198	PhosphoSitePlus	COSMIC	3.516	Up-regulation
AGC_PDK1_PDPK1_ST	P05106	ITGB3	O15530	PDPK1	T779	E775K	775	Missense	distal	-4	no	4.971	4.970	PhosphoSitePlus	COSMIC	3.516	Down-regulation
AGC_PDK1_PDPK1_ST	P23443	RPS6KB1	O15530	PDPK1	T252	H245Y	245	Missense	distal	-7	no	7.479	6.959	EPSD;PhosphoSitePlus	COSMIC	3.516	Down-regulation
AGC_PDK1_PDPK1_ST	P23443	RPS6KB1	O15530	PDPK1	T390	P391S	391	Missense	proximal	1	no	5.496	2.701	EPSD	COSMIC	3.516	Loss
AGC_PDK1_PDPK1_ST	P23443	RPS6KB1	O15530	PDPK1	T390	R388G	388	Missense	proximal	-2	no	5.496	5.455	EPSD	COSMIC	3.516	Down-regulation
AGC_PDK1_PDPK1_ST	P23443	RPS6KB1	O15530	PDPK1	S394	P391S	391	Missense	distal	-3	no	5.823	6.150	PhosphoSitePlus;EPSD	COSMIC	3.516	Up-regulation
AGC_PDK1_PDPK1_ST	P23443	RPS6KB1	O15530	PDPK1	S394	S401N	401	Missense	distal	7	no	5.823	5.776	PhosphoSitePlus;EPSD	COSMIC;CCLE	3.516	Down-regulation
AGC_PDK1_PDPK1_ST	P23443	RPS6KB1	O15530	PDPK1	S394	S398T	398	Missense	distal	4	no	5.823	5.886	PhosphoSitePlus;EPSD	COSMIC	3.516	Up-regulation
AGC_PDK1_PDPK1_ST	P23443	RPS6KB1	O15530	PDPK1	S394	R388G	388	Missense	distal	-6	no	5.823	5.786	PhosphoSitePlus;EPSD	COSMIC	3.516	Down-regulation
AGC_PDK1_PDPK1_ST	P23443	RPS6KB1	O15530	PDPK1	T412	T412A	412	Missense	central	0	yes	6.474	0.000	EPSD;PhosphoSitePlus	COSMIC	3.516	Loss
AGC_PDK1_PDPK1_ST	P23443	RPS6KB1	O15530	PDPK1	T412	V414E	414	Missense	proximal	2	no	6.474	6.427	EPSD;PhosphoSitePlus	COSMIC	3.516	Down-regulation
AGC_PDK1_PDPK1_ST	P23443	RPS6KB1	O15530	PDPK1	T444	G440A	440	Missense	distal	-4	no	6.492	6.536	EPSD	COSMIC	3.516	Up-regulation
AGC_PDK1_PDPK1_ST	P23443	RPS6KB1	O15530	PDPK1	T444	P445L	445	Missense	proximal	1	no	6.492	4.073	EPSD	COSMIC	3.516	Down-regulation
AGC_PDK1_PDPK1_ST	P23443	RPS6KB1	O15530	PDPK1	T487	A494T	494	Missense	distal	7	no	3.355	3.580	EPSD	COSMIC	3.516	Gain
AGC_PDK1_PDPK1_ST	P17612	PRKACA	O15530	PDPK1	S54	R57W	57	Missense	distal	3	no	6.069	5.965	EPSD	COSMIC	3.516	Down-regulation
AGC_PDK1_PDPK1_ST	P17612	PRKACA	O15530	PDPK1	S54	R57L	57	Missense	distal	3	no	6.069	5.870	EPSD	COSMIC	3.516	Down-regulation
AGC_PDK1_PDPK1_ST	P17612	PRKACA	O15530	PDPK1	S54	T49I	49	Missense	distal	-5	no	6.069	6.313	EPSD	COSMIC	3.516	Up-regulation
AGC_PDK1_PDPK1_ST	P17612	PRKACA	O15530	PDPK1	T198	W197S	197	Missense	proximal	-1	no	5.939	6.237	PhosphoSitePlus	COSMIC	3.516	Up-regulation
AGC_PDK1_PDPK1_ST	P17612	PRKACA	O15530	PDPK1	T198	R195C	195	Missense	distal	-3	no	5.939	5.073	PhosphoSitePlus	COSMIC	3.516	Down-regulation
AGC_PDK1_PDPK1_ST	P31749	AKT1	O15530	PDPK1	T72	C77F	77	Missense	distal	5	no	5.536	5.537	EPSD	COSMIC	3.516	Up-regulation
AGC_PDK1_PDPK1_ST	P31749	AKT1	O15530	PDPK1	T72	R67Q	67	Missense	distal	-5	no	5.536	5.516	EPSD	COSMIC	3.516	Down-regulation
AGC_PDK1_PDPK1_ST	P31749	AKT1	O15530	PDPK1	T72	R76H	76	Missense	distal	4	no	5.536	5.228	EPSD	COSMIC	3.516	Down-regulation
AGC_PDK1_PDPK1_ST	P31749	AKT1	O15530	PDPK1	T72	R69L	69	Missense	distal	-3	no	5.536	4.880	EPSD	COSMIC	3.516	Down-regulation
AGC_PDK1_PDPK1_ST	P31749	AKT1	O15530	PDPK1	T72	Q79R	79	Missense	distal	7	no	5.536	5.645	EPSD	COSMIC	3.516	Up-regulation
AGC_PDK1_PDPK1_ST	P31749	AKT1	O15530	PDPK1	T72	P70L	70	Missense	proximal	-2	no	5.536	5.368	EPSD	COSMIC	3.516	Down-regulation
AGC_PDK1_PDPK1_ST	P31749	AKT1	O15530	PDPK1	T87	I84T	84	Missense	distal	-3	no	3.040	4.320	EPSD	COSMIC	3.516	Gain
AGC_PDK1_PDPK1_ST	P31749	AKT1	O15530	PDPK1	T92	E91K	91	Missense	proximal	-1	no	3.431	3.551	EPSD	COSMIC	3.516	Gain
AGC_PDK1_PDPK1_ST	P31749	AKT1	O15530	PDPK1	T92	W99R	99	Missense	distal	7	no	3.431	3.614	EPSD	COSMIC	3.516	Gain
AGC_PDK1_PDPK1_ST	P31749	AKT1	O15530	PDPK1	S124	G123D	123	Missense	proximal	-1	no	6.247	6.093	EPSD	COSMIC	3.516	Down-regulation
AGC_PDK1_PDPK1_ST	P31749	AKT1	O15530	PDPK1	S124	D127N	127	Missense	distal	3	no	6.247	6.290	EPSD	COSMIC	3.516	Up-regulation
AGC_PDK1_PDPK1_ST	P31749	AKT1	O15530	PDPK1	S137	P141L	141	Missense	distal	4	no	3.627	2.879	EPSD	COSMIC	3.516	Loss
AGC_PDK1_PDPK1_ST	P31749	AKT1	O15530	PDPK1	S137	E133Q	133	Missense	distal	-4	no	3.627	3.604	EPSD	COSMIC	3.516	Down-regulation
AGC_PDK1_PDPK1_ST	P31749	AKT1	O15530	PDPK1	S137	S137F	137	Missense	central	0	yes	3.627	0.000	EPSD	COSMIC	3.516	Loss
AGC_PDK1_PDPK1_ST	P31749	AKT1	O15530	PDPK1	S137	S137Y	137	Missense	central	0	yes	3.627	0.000	EPSD	COSMIC	3.516	Loss
AGC_PDK1_PDPK1_ST	P31749	AKT1	O15530	PDPK1	S137	G130R	130	Missense	distal	-7	no	3.627	3.431	EPSD	COSMIC	3.516	Loss
AGC_PDK1_PDPK1_ST	P31749	AKT1	O15530	PDPK1	S137	A139T	139	Missense	proximal	2	no	3.627	3.657	EPSD	COSMIC	3.516	Up-regulation
AGC_PDK1_PDPK1_ST	P31749	AKT1	O15530	PDPK1	S137	E135Q	135	Missense	proximal	-2	no	3.627	3.669	EPSD	COSMIC	3.516	Up-regulation
AGC_PDK1_PDPK1_ST	P31749	AKT1	O15530	PDPK1	T308	M306T	306	Missense	proximal	-2	no	10.175	10.237	EPSD;PhosphoSitePlus	COSMIC	3.516	Up-regulation
AGC_PDK1_PDPK1_ST	P31749	AKT1	O15530	PDPK1	T308	M306L	306	Missense	proximal	-2	no	10.175	10.050	EPSD;PhosphoSitePlus	COSMIC	3.516	Down-regulation
AGC_PDK1_PDPK1_ST	P31749	AKT1	O15530	PDPK1	T308	M306I	306	Missense	proximal	-2	no	10.175	9.995	EPSD;PhosphoSitePlus	COSMIC	3.516	Down-regulation
AGC_PDK1_PDPK1_ST	P31749	AKT1	O15530	PDPK1	T308	T312I	312	Missense	distal	4	no	10.175	8.820	EPSD;PhosphoSitePlus	COSMIC	3.516	Down-regulation
AGC_PDK1_PDPK1_ST	P31749	AKT1	O15530	PDPK1	T308	G303S	303	Missense	distal	-5	no	10.175	10.187	EPSD;PhosphoSitePlus	COSMIC	3.516	Up-regulation
AGC_PDK1_PDPK1_ST	P31749	AKT1	O15530	PDPK1	T450	P452L	452	Missense	proximal	2	no	5.080	5.042	EPSD	COSMIC	3.516	Down-regulation
AGC_PDK1_PDPK1_ST	P31749	AKT1	O15530	PDPK1	T450	M446I	446	Missense	distal	-4	no	5.080	5.261	EPSD	COSMIC	3.516	Up-regulation
AGC_PDK1_PDPK1_ST	P31749	AKT1	O15530	PDPK1	T450	I447F	447	Missense	distal	-3	no	5.080	4.932	EPSD	COSMIC	3.516	Down-regulation
AGC_PDK1_PDPK1_ST	P31749	AKT1	O15530	PDPK1	T450	T443M	443	Missense	distal	-7	no	5.080	5.085	EPSD	COSMIC	3.516	Up-regulation
AGC_PDK1_PDPK1_ST	P31749	AKT1	O15530	PDPK1	S473	S477N	477	Missense	distal	4	no	5.258	4.653	PhosphoSitePlus;EPSD	COSMIC	3.516	Down-regulation
AGC_PDK1_PDPK1_ST	P31749	AKT1	O15530	PDPK1	S473	P470L	470	Missense	distal	-3	no	5.258	4.799	PhosphoSitePlus;EPSD	COSMIC	3.516	Down-regulation
AGC_PDK1_PDPK1_ST	O60331	PIP5K1C	O15530	PDPK1	T69	E68K	68	Missense	proximal	-1	no	4.887	5.007	EPSD	COSMIC	3.516	Up-regulation
AGC_PDK1_PDPK1_ST	O60331	PIP5K1C	O15530	PDPK1	T69	A65T	65	Missense	distal	-4	no	4.887	4.840	EPSD	COSMIC	3.516	Down-regulation
AGC_PDK1_PDPK1_ST	O60331	PIP5K1C	O15530	PDPK1	T69	S66F	66	Missense	distal	-3	no	4.887	3.418	EPSD	COSMIC	3.516	Loss
AGC_PDK1_PDPK1_ST	O60331	PIP5K1C	O15530	PDPK1	T70	E68K	68	Missense	proximal	-2	no	3.767	3.780	EPSD	COSMIC	3.516	Up-regulation
AGC_PDK1_PDPK1_ST	O60331	PIP5K1C	O15530	PDPK1	T70	A65T	65	Missense	distal	-5	no	3.767	3.786	EPSD	COSMIC	3.516	Up-regulation
AGC_PDK1_PDPK1_ST	O60331	PIP5K1C	O15530	PDPK1	T70	S66F	66	Missense	distal	-4	no	3.767	3.930	EPSD	COSMIC	3.516	Up-regulation
AGC_PDK1_PDPK1_ST	O60331	PIP5K1C	O15530	PDPK1	S95	V102M	102	Missense	distal	7	no	3.944	4.086	EPSD	COSMIC	3.516	Up-regulation
AGC_PDK1_PDPK1_ST	O60331	PIP5K1C	O15530	PDPK1	T442	T442M	442	Missense	central	0	yes	3.610	0.000	EPSD	COSMIC;CCLE	3.516	Loss
AGC_PDK1_PDPK1_ST	O60331	PIP5K1C	O15530	PDPK1	T442	S448F	448	Missense	distal	6	no	3.610	3.612	EPSD	COSMIC	3.516	Up-regulation
AGC_PDK1_PDPK1_ST	O60331	PIP5K1C	O15530	PDPK1	S448	T442M	442	Missense	distal	-6	no	4.948	4.941	PhosphoSitePlus	COSMIC;CCLE	3.516	Down-regulation
AGC_PDK1_PDPK1_ST	O60331	PIP5K1C	O15530	PDPK1	S448	S448F	448	Missense	central	0	yes	4.948	0.000	PhosphoSitePlus	COSMIC	3.516	Loss
AGC_PDK1_PDPK1_ST	O60331	PIP5K1C	O15530	PDPK1	S515	T512M	512	Missense	distal	-3	no	6.523	6.375	EPSD	COSMIC	3.516	Down-regulation
AGC_PDK1_PDPK1_ST	O60331	PIP5K1C	O15530	PDPK1	S515	E517K	517	Missense	proximal	2	no	6.523	6.503	EPSD	COSMIC	3.516	Down-regulation
AGC_PDK1_PDPK1_ST	O60331	PIP5K1C	O15530	PDPK1	S539	R538L	538	Missense	proximal	-1	no	6.158	5.824	EPSD	COSMIC	3.516	Down-regulation
AGC_PDK1_PDPK1_ST	O60331	PIP5K1C	O15530	PDPK1	S539	S532P	532	Missense	distal	-7	no	6.158	6.184	EPSD	COSMIC;GDSC;CCLE	3.516	Up-regulation
AGC_PDK1_PDPK1_ST	O60331	PIP5K1C	O15530	PDPK1	T543	R538L	538	Missense	distal	-5	no	3.666	3.879	EPSD	COSMIC	3.516	Up-regulation
AGC_PDK1_PDPK1_ST	O60331	PIP5K1C	O15530	PDPK1	S650	L652F	652	Missense	proximal	2	no	4.892	4.822	EPSD	COSMIC;CCLE	3.516	Down-regulation
AGC_PDK1_PDPK1_ST	O60331	PIP5K1C	O15530	PDPK1	S650	H653P	653	Missense	distal	3	no	4.892	4.970	EPSD	COSMIC	3.516	Up-regulation
AGC_PDK1_PDPK1_ST	Q02750	MAP2K1	O15530	PDPK1	T23	S24Y	24	Missense	proximal	1	no	1.720	3.678	EPSD	COSMIC	3.516	Gain
AGC_PDK1_PDPK1_ST	Q02750	MAP2K1	O15530	PDPK1	S222	L215F	215	Missense	distal	-7	no	8.613	8.018	PhosphoSitePlus	COSMIC	3.516	Down-regulation
AGC_PDK1_PDPK1_ST	Q02750	MAP2K1	O15530	PDPK1	S222	Y229H	229	Missense	distal	7	no	8.613	8.571	PhosphoSitePlus	COSMIC	3.516	Down-regulation
AGC_PDK1_PDPK1_ST	Q02750	MAP2K1	O15530	PDPK1	S222	S218F	218	Missense	distal	-4	no	8.613	8.776	PhosphoSitePlus	COSMIC	3.516	Up-regulation
AGC_PDK1_PDPK1_ST	Q02750	MAP2K1	O15530	PDPK1	S231	Y229H	229	Missense	proximal	-2	no	4.679	4.746	EPSD	COSMIC	3.516	Up-regulation
AGC_PDK1_PDPK1_ST	Q02750	MAP2K1	O15530	PDPK1	T286	A283V	283	Missense	distal	-3	no	3.876	4.103	EPSD	COSMIC	3.516	Up-regulation
AGC_PDK1_PDPK1_ST	Q02750	MAP2K1	O15530	PDPK1	T286	P293S	293	Missense	distal	7	no	3.876	3.715	EPSD	COSMIC	3.516	Down-regulation
AGC_PDK1_PDPK1_ST	Q02750	MAP2K1	O15530	PDPK1	T286	R291K	291	Missense	distal	5	no	3.876	3.324	EPSD	COSMIC	3.516	Loss
AGC_PDK1_PDPK1_ST	Q02750	MAP2K1	O15530	PDPK1	T292	P293S	293	Missense	proximal	1	no	5.026	2.232	EPSD	COSMIC	3.516	Loss
AGC_PDK1_PDPK1_ST	Q02750	MAP2K1	O15530	PDPK1	T292	R291K	291	Missense	proximal	-1	no	5.026	5.007	EPSD	COSMIC	3.516	Down-regulation
AGC_PDK1_PDPK1_ST	Q02750	MAP2K1	O15530	PDPK1	S299	P306H	306	Missense	distal	7	no	3.809	3.587	EPSD	COSMIC	3.516	Down-regulation
AGC_PDK1_PDPK1_ST	Q02750	MAP2K1	O15530	PDPK1	S299	G301E	301	Missense	proximal	2	no	3.809	3.796	EPSD	COSMIC	3.516	Down-regulation
AGC_PDK1_PDPK1_ST	Q02750	MAP2K1	O15530	PDPK1	S299	P293S	293	Missense	distal	-6	no	3.809	3.807	EPSD	COSMIC	3.516	Down-regulation
AGC_PDK1_PDPK1_ST	Q02750	MAP2K1	O15530	PDPK1	T386	P387S	387	Missense	proximal	1	no	3.786	0.991	EPSD	COSMIC	3.516	Loss
AGC_PDK1_PDPK1_ST	Q02750	MAP2K1	O15530	PDPK1	T386	A390T	390	Missense	distal	4	no	3.786	4.275	EPSD	COSMIC;GDSC	3.516	Up-regulation
AGC_PDK1_PDPK1_ST	Q02750	MAP2K1	O15530	PDPK1	T386	N382H	382	Missense	distal	-4	no	3.786	3.809	EPSD	COSMIC	3.516	Up-regulation
AGC_PDK1_PDPK1_ST	Q96BR1	SGK3	O15530	PDPK1	S142	S144L	144	Missense	proximal	2	no	3.577	3.492	EPSD	COSMIC	3.516	Loss
AGC_PDK1_PDPK1_ST	Q9Y243	AKT3	O15530	PDPK1	S120	I125M	125	Missense	distal	5	no	3.284	4.902	EPSD	COSMIC	3.516	Gain
AGC_PDK1_PDPK1_ST	Q9Y243	AKT3	O15530	PDPK1	T305	T298A	298	Missense	distal	-7	no	10.850	10.448	PhosphoSitePlus	COSMIC;GDSC;CCLE	3.516	Down-regulation
AGC_PDK1_PDPK1_ST	Q9Y243	AKT3	O15530	PDPK1	T305	P310R	310	Missense	distal	5	no	10.850	10.431	PhosphoSitePlus	COSMIC	3.516	Down-regulation
AGC_PDK1_PDPK1_ST	Q9Y243	AKT3	O15530	PDPK1	T447	Y452C	452	Missense	distal	5	no	4.706	4.112	EPSD	COSMIC	3.516	Down-regulation
AGC_PDK1_PDPK1_ST	Q9Y243	AKT3	O15530	PDPK1	T447	E450K	450	Missense	distal	3	no	4.706	4.562	EPSD	COSMIC	3.516	Down-regulation
AGC_PDK1_PDPK1_ST	Q9Y243	AKT3	O15530	PDPK1	S472	P469L	469	Missense	distal	-3	no	5.564	5.105	EPSD	COSMIC	3.516	Down-regulation
AGC_PDK1_PDPK1_ST	Q9Y243	AKT3	O15530	PDPK1	S472	R465Q	465	Missense	distal	-7	no	5.564	5.275	EPSD	COSMIC;GDSC;CCLE	3.516	Down-regulation
AGC_PDK1_PDPK1_ST	Q9Y243	AKT3	O15530	PDPK1	S472	P466L	466	Missense	distal	-6	no	5.564	5.653	EPSD	COSMIC;GDSC;CCLE	3.516	Up-regulation
AGC_PDK1_PDPK1_ST	Q9Y243	AKT3	O15530	PDPK1	S472	P466T	466	Missense	distal	-6	no	5.564	5.554	EPSD	COSMIC	3.516	Down-regulation
AGC_PDK1_PDPK1_ST	Q9Y243	AKT3	O15530	PDPK1	S472	R465W	465	Missense	distal	-7	no	5.564	4.789	EPSD	COSMIC	3.516	Down-regulation
AGC_PDK1_PDPK1_ST	O00141	SGK1	O15530	PDPK1	S74	Q81R	81	Missense	distal	7	no	5.262	5.370	EPSD	COSMIC	3.516	Up-regulation
AGC_PDK1_PDPK1_ST	O00141	SGK1	O15530	PDPK1	S74	N72K	72	Missense	proximal	-2	no	5.262	5.188	EPSD	COSMIC	3.516	Down-regulation
AGC_PDK1_PDPK1_ST	O00141	SGK1	O15530	PDPK1	S74	S78A	78	Missense	distal	4	no	5.262	4.836	EPSD	COSMIC	3.516	Down-regulation
AGC_PDK1_PDPK1_ST	O00141	SGK1	O15530	PDPK1	S74	A71T	71	Missense	distal	-3	no	5.262	5.847	EPSD	COSMIC	3.516	Up-regulation
AGC_PDK1_PDPK1_ST	O00141	SGK1	O15530	PDPK1	S74	P75S	75	Missense	proximal	1	no	5.262	2.467	EPSD	COSMIC	3.516	Loss
AGC_PDK1_PDPK1_ST	O00141	SGK1	O15530	PDPK1	S74	N72Y	72	Missense	proximal	-2	no	5.262	5.181	EPSD	COSMIC;CCLE	3.516	Down-regulation
AGC_PDK1_PDPK1_ST	O00141	SGK1	O15530	PDPK1	S78	Q81R	81	Missense	distal	3	no	4.714	4.597	EPSD	COSMIC	3.516	Down-regulation
AGC_PDK1_PDPK1_ST	O00141	SGK1	O15530	PDPK1	S78	N72K	72	Missense	distal	-6	no	4.714	4.743	EPSD	COSMIC	3.516	Up-regulation
AGC_PDK1_PDPK1_ST	O00141	SGK1	O15530	PDPK1	S78	S78A	78	Missense	central	0	yes	4.714	0.000	EPSD	COSMIC	3.516	Loss
AGC_PDK1_PDPK1_ST	O00141	SGK1	O15530	PDPK1	S78	A71T	71	Missense	distal	-7	no	4.714	5.116	EPSD	COSMIC	3.516	Up-regulation
AGC_PDK1_PDPK1_ST	O00141	SGK1	O15530	PDPK1	S78	P75S	75	Missense	distal	-3	no	4.714	5.041	EPSD	COSMIC	3.516	Up-regulation
AGC_PDK1_PDPK1_ST	O00141	SGK1	O15530	PDPK1	S78	N72Y	72	Missense	distal	-6	no	4.714	4.779	EPSD	COSMIC;CCLE	3.516	Up-regulation
AGC_PDK1_PDPK1_ST	O00141	SGK1	O15530	PDPK1	S88	S89F	89	Missense	proximal	1	no	2.381	5.718	EPSD	COSMIC	3.516	Gain
AGC_PDK1_PDPK1_ST	O00141	SGK1	O15530	PDPK1	T254	S255P	255	Missense	proximal	1	no	0.850	3.645	EPSD	COSMIC	3.516	Gain
AGC_PDK1_PDPK1_ST	O00141	SGK1	O15530	PDPK1	T256	N251S	251	Missense	distal	-5	no	9.909	9.876	PhosphoSitePlus	COSMIC;CCLE	3.516	Down-regulation
AGC_PDK1_PDPK1_ST	O00141	SGK1	O15530	PDPK1	T256	S252T	252	Missense	distal	-4	no	9.909	9.877	PhosphoSitePlus	COSMIC	3.516	Down-regulation
AGC_PDK1_PDPK1_ST	O00141	SGK1	O15530	PDPK1	T256	C258R	258	Missense	proximal	2	no	9.909	9.983	PhosphoSitePlus	COSMIC	3.516	Up-regulation
AGC_PDK1_PDPK1_ST	O00141	SGK1	O15530	PDPK1	T256	S255P	255	Missense	proximal	-1	no	9.909	9.889	PhosphoSitePlus	COSMIC	3.516	Down-regulation
AGC_PDK1_PDPK1_ST	O00141	SGK1	O15530	PDPK1	T256	T253N	253	Missense	distal	-3	no	9.909	9.368	PhosphoSitePlus	COSMIC	3.516	Down-regulation
AGC_PDK1_PDPK1_ST	O00141	SGK1	O15530	PDPK1	T369	P371L	371	Missense	proximal	2	no	3.969	3.930	EPSD	COSMIC	3.516	Down-regulation
AGC_PDK1_PDPK1_ST	O00141	SGK1	O15530	PDPK1	T369	K367T	367	Missense	proximal	-2	no	3.969	4.120	EPSD	COSMIC	3.516	Up-regulation
AGC_PDK1_PDPK1_ST	O00141	SGK1	O15530	PDPK1	S401	V394A	394	Missense	distal	-7	no	3.654	3.665	EPSD	COSMIC	3.516	Up-regulation
AGC_PDK1_PDPK1_ST	O00141	SGK1	O15530	PDPK1	S422	E416G	416	Missense	distal	-6	no	4.947	4.879	EPSD	COSMIC	3.516	Down-regulation
AGC_PDK1_PDPK1_ST	O00141	SGK1	O15530	PDPK1	S422	A424S	424	Missense	proximal	2	no	4.947	4.999	EPSD	COSMIC	3.516	Up-regulation
AGC_PDK1_PDPK1_ST	O00141	SGK1	O15530	PDPK1	S422	T427M	427	Missense	distal	5	no	4.947	4.693	EPSD	COSMIC	3.516	Down-regulation
AGC_PDK1_PDPK1_ST	P36507	MAP2K2	O15530	PDPK1	S226	R231H	231	Missense	distal	5	no	8.691	8.560	PhosphoSitePlus	COSMIC	3.516	Down-regulation
AGC_PDK1_PDPK1_ST	P36507	MAP2K2	O15530	PDPK1	S226	S222Y	222	Missense	distal	-4	no	8.691	8.756	PhosphoSitePlus	COSMIC	3.516	Up-regulation
AGC_PDK1_PDPK1_ST	P36507	MAP2K2	O15530	PDPK1	S226	M223V	223	Missense	distal	-3	no	8.691	8.481	PhosphoSitePlus	COSMIC	3.516	Down-regulation
AGC_PDK1_PDPK1_ST	P36507	MAP2K2	O15530	PDPK1	S295	P300R	300	Missense	distal	5	no	4.451	4.032	EPSD	COSMIC	3.516	Down-regulation
AGC_PDK1_PDPK1_ST	P36507	MAP2K2	O15530	PDPK1	S295	R299M	299	Missense	distal	4	no	4.451	4.277	EPSD	COSMIC	3.516	Down-regulation
AGC_PDK1_PDPK1_ST	P36507	MAP2K2	O15530	PDPK1	S295	R299S	299	Missense	distal	4	no	4.451	4.777	EPSD	COSMIC	3.516	Up-regulation
AGC_PDK1_PDPK1_ST	P36507	MAP2K2	O15530	PDPK1	S295	P291H	291	Missense	distal	-4	no	4.451	4.500	EPSD	COSMIC	3.516	Up-regulation
AGC_PDK1_PDPK1_ST	P36507	MAP2K2	O15530	PDPK1	S295	R297Q	297	Missense	proximal	2	no	4.451	4.393	EPSD	COSMIC	3.516	Down-regulation
AGC_PDK1_PDPK1_ST	P36507	MAP2K2	O15530	PDPK1	T394	R388Q	388	Missense	distal	-6	no	4.121	4.131	EPSD	COSMIC	3.516	Up-regulation
AGC_PDK1_PDPK1_ST	P36507	MAP2K2	O15530	PDPK1	T394	R388W	388	Missense	distal	-6	no	4.121	4.194	EPSD	COSMIC	3.516	Up-regulation
AGC_PDK1_PDPK1_ST	P36507	MAP2K2	O15530	PDPK1	T394	R388G	388	Missense	distal	-6	no	4.121	4.084	EPSD	COSMIC	3.516	Down-regulation
AGC_PDK1_PDPK1_ST	Q13153	PAK1	O15530	PDPK1	S144	K141E	141	Missense	distal	-3	no	4.092	3.756	EPSD	COSMIC	3.516	Down-regulation
AGC_PDK1_PDPK1_ST	Q13153	PAK1	O15530	PDPK1	S144	Y142C	142	Missense	proximal	-2	no	4.092	4.048	EPSD	COSMIC	3.516	Down-regulation
AGC_PDK1_PDPK1_ST	Q13153	PAK1	O15530	PDPK1	S144	E151K	151	Missense	distal	7	no	4.092	4.051	EPSD	COSMIC	3.516	Down-regulation
AGC_PDK1_PDPK1_ST	Q13153	PAK1	O15530	PDPK1	T167	E166Q	166	Missense	proximal	-1	no	5.260	5.381	EPSD	COSMIC	3.516	Up-regulation
AGC_PDK1_PDPK1_ST	Q13153	PAK1	O15530	PDPK1	T167	A169V	169	Missense	proximal	2	no	5.260	5.290	EPSD	COSMIC	3.516	Up-regulation
AGC_PDK1_PDPK1_ST	Q13153	PAK1	O15530	PDPK1	S220	T219A	219	Missense	proximal	-1	no	5.995	5.840	EPSD	COSMIC	3.516	Down-regulation
AGC_PDK1_PDPK1_ST	Q13153	PAK1	O15530	PDPK1	S220	I222V	222	Missense	proximal	2	no	5.995	6.113	EPSD	COSMIC	3.516	Up-regulation
AGC_PDK1_PDPK1_ST	Q13153	PAK1	O15530	PDPK1	S220	P221A	221	Missense	proximal	1	no	5.995	1.450	EPSD	COSMIC	3.516	Loss
AGC_PDK1_PDPK1_ST	Q13153	PAK1	O15530	PDPK1	S223	T219A	219	Missense	distal	-4	no	3.592	3.639	EPSD	COSMIC	3.516	Up-regulation
AGC_PDK1_PDPK1_ST	Q13153	PAK1	O15530	PDPK1	S223	I222V	222	Missense	proximal	-1	no	3.592	3.922	EPSD	COSMIC	3.516	Up-regulation
AGC_PDK1_PDPK1_ST	Q13153	PAK1	O15530	PDPK1	S223	P221A	221	Missense	proximal	-2	no	3.592	3.530	EPSD	COSMIC	3.516	Down-regulation
AGC_PDK1_PDPK1_ST	Q13153	PAK1	O15530	PDPK1	S223	N228H	228	Missense	distal	5	no	3.592	3.534	EPSD	COSMIC	3.516	Down-regulation
AGC_PDK1_PDPK1_ST	Q13153	PAK1	O15530	PDPK1	T415	I414K	414	Missense	proximal	-1	no	3.666	4.040	EPSD	COSMIC	3.516	Up-regulation
AGC_PDK1_PDPK1_ST	Q13153	PAK1	O15530	PDPK1	T415	R421W	421	Missense	distal	6	no	3.666	3.668	EPSD	COSMIC	3.516	Up-regulation
AGC_PDK1_PDPK1_ST	Q13153	PAK1	O15530	PDPK1	T415	R421Q	421	Missense	distal	6	no	3.666	3.667	EPSD	COSMIC	3.516	Up-regulation
AGC_PDK1_PDPK1_ST	Q13153	PAK1	O15530	PDPK1	T415	A412P	412	Missense	distal	-3	no	3.666	3.965	EPSD	COSMIC	3.516	Up-regulation
AGC_PDK1_PDPK1_ST	Q13153	PAK1	O15530	PDPK1	T415	E417V	417	Missense	proximal	2	no	3.666	3.714	EPSD	COSMIC	3.516	Up-regulation
AGC_PDK1_PDPK1_ST	Q13153	PAK1	O15530	PDPK1	T415	R421K	421	Missense	distal	6	no	3.666	3.667	EPSD	COSMIC	3.516	Up-regulation
AGC_PDK1_PDPK1_ST	Q13153	PAK1	O15530	PDPK1	S422	R421W	421	Missense	proximal	-1	no	3.640	3.404	EPSD	COSMIC	3.516	Loss
AGC_PDK1_PDPK1_ST	Q13153	PAK1	O15530	PDPK1	S422	P428L	428	Missense	distal	6	no	3.640	3.641	EPSD	COSMIC	3.516	Up-regulation
AGC_PDK1_PDPK1_ST	Q13153	PAK1	O15530	PDPK1	S422	R421Q	421	Missense	proximal	-1	no	3.640	3.622	EPSD	COSMIC	3.516	Down-regulation
AGC_PDK1_PDPK1_ST	Q13153	PAK1	O15530	PDPK1	S422	M424I	424	Missense	proximal	2	no	3.640	3.478	EPSD	COSMIC	3.516	Loss
AGC_PDK1_PDPK1_ST	Q13153	PAK1	O15530	PDPK1	S422	E417V	417	Missense	distal	-5	no	3.640	3.696	EPSD	COSMIC	3.516	Up-regulation
AGC_PDK1_PDPK1_ST	Q13153	PAK1	O15530	PDPK1	S422	R421K	421	Missense	proximal	-1	no	3.640	3.621	EPSD	COSMIC	3.516	Down-regulation
AGC_PDK1_PDPK1_ST	Q13153	PAK1	O15530	PDPK1	T423	R421W	421	Missense	proximal	-2	no	6.335	6.229	PhosphoSitePlus	COSMIC	3.516	Down-regulation
AGC_PDK1_PDPK1_ST	Q13153	PAK1	O15530	PDPK1	T423	P428L	428	Missense	distal	5	no	6.335	5.341	PhosphoSitePlus	COSMIC	3.516	Down-regulation
AGC_PDK1_PDPK1_ST	Q13153	PAK1	O15530	PDPK1	T423	R421Q	421	Missense	proximal	-2	no	6.335	6.276	PhosphoSitePlus	COSMIC	3.516	Down-regulation
AGC_PDK1_PDPK1_ST	Q13153	PAK1	O15530	PDPK1	T423	M424I	424	Missense	proximal	1	no	6.335	2.453	PhosphoSitePlus	COSMIC	3.516	Loss
AGC_PDK1_PDPK1_ST	Q13153	PAK1	O15530	PDPK1	T423	E417V	417	Missense	distal	-6	no	6.335	6.346	PhosphoSitePlus	COSMIC	3.516	Up-regulation
AGC_PDK1_PDPK1_ST	Q13153	PAK1	O15530	PDPK1	T423	R421K	421	Missense	proximal	-2	no	6.335	6.247	PhosphoSitePlus	COSMIC	3.516	Down-regulation
AGC_PDK1_PDPK1_ST	Q13153	PAK1	O15530	PDPK1	T481	I476N	476	Missense	distal	-5	no	5.140	4.857	EPSD	COSMIC	3.516	Down-regulation
AGC_PDK1_PDPK1_ST	Q13153	PAK1	O15530	PDPK1	T481	E483K	483	Missense	proximal	2	no	5.140	5.121	EPSD	COSMIC	3.516	Down-regulation
AGC_PDK1_PDPK1_ST	Q13153	PAK1	O15530	PDPK1	T481	N486D	486	Missense	distal	5	no	5.140	5.096	EPSD	COSMIC	3.516	Down-regulation
AGC_PDK1_PDPK1_ST	Q13153	PAK1	O15530	PDPK1	T481	I476T	476	Missense	distal	-5	no	5.140	4.896	EPSD	COSMIC	3.516	Down-regulation
AGC_PDK1_PDPK1_ST	Q13153	PAK1	O15530	PDPK1	T481	N486S	486	Missense	distal	5	no	5.140	5.745	EPSD	COSMIC	3.516	Up-regulation
AGC_PDK1_PDPK1_ST	Q13153	PAK1	O15530	PDPK1	T531	S528F	528	Missense	distal	-3	no	4.012	2.543	EPSD	COSMIC	3.516	Loss
AGC_PDK1_PDPK1_ST	Q13153	PAK1	O15530	PDPK1	T531	L533M	533	Missense	proximal	2	no	4.012	4.118	EPSD	COSMIC	3.516	Up-regulation
AGC_PDK1_PDPK1_ST	Q05655	PRKCD	O15530	PDPK1	S302	A298T	298	Missense	distal	-4	no	4.135	4.088	EPSD	COSMIC	3.516	Down-regulation
AGC_PDK1_PDPK1_ST	Q05655	PRKCD	O15530	PDPK1	S302	S307L	307	Missense	distal	5	no	4.135	3.028	EPSD	COSMIC;GDSC;CCLE	3.516	Loss
AGC_PDK1_PDPK1_ST	Q05655	PRKCD	O15530	PDPK1	S302	S306Y	306	Missense	distal	4	no	4.135	3.270	EPSD	COSMIC;GDSC;CCLE	3.516	Loss
AGC_PDK1_PDPK1_ST	Q05655	PRKCD	O15530	PDPK1	S302	S299F	299	Missense	distal	-3	no	4.135	2.666	EPSD	COSMIC	3.516	Loss
AGC_PDK1_PDPK1_ST	Q05655	PRKCD	O15530	PDPK1	T451	A450V	450	Missense	proximal	-1	no	4.677	4.699	EPSD	COSMIC	3.516	Up-regulation
AGC_PDK1_PDPK1_ST	Q05655	PRKCD	O15530	PDPK1	S664	F660L	660	Missense	distal	-4	no	5.602	5.507	EPSD	COSMIC	3.516	Down-regulation
AGC_PDK1_PDPK1_ST	Q05655	PRKCD	O15530	PDPK1	S664	A661V	661	Missense	distal	-3	no	5.602	5.829	EPSD	COSMIC	3.516	Up-regulation
AGC_PDK1_PDPK1_ST	Q99683	MAP3K5	O15530	PDPK1	S83	G81S	81	Missense	proximal	-2	no	5.317	5.407	EPSD	COSMIC	3.516	Up-regulation
AGC_PDK1_PDPK1_ST	Q99683	MAP3K5	O15530	PDPK1	S83	G87S	87	Missense	distal	4	no	5.317	6.255	EPSD	COSMIC	3.516	Up-regulation
AGC_PDK1_PDPK1_ST	Q99683	MAP3K5	O15530	PDPK1	T838	P834S	834	Missense	distal	-4	no	5.741	5.784	EPSD	COSMIC	3.516	Up-regulation
AGC_PDK1_PDPK1_ST	Q99683	MAP3K5	O15530	PDPK1	T838	I832T	832	Missense	distal	-6	no	5.741	5.611	EPSD	COSMIC;GDSC;CCLE	3.516	Down-regulation
AGC_PDK1_PDPK1_ST	Q99683	MAP3K5	O15530	PDPK1	T838	G841C	841	Missense	distal	3	no	5.741	5.336	EPSD	COSMIC	3.516	Down-regulation
AGC_PDK1_PDPK1_ST	Q99683	MAP3K5	O15530	PDPK1	S966	V969I	969	Missense	distal	3	no	6.515	6.282	PhosphoSitePlus	COSMIC	3.516	Down-regulation
AGC_PDK1_PDPK1_ST	Q99683	MAP3K5	O15530	PDPK1	S979	G983S	983	Missense	distal	4	no	2.612	3.550	EPSD	COSMIC;GDSC;CCLE	3.516	Gain
AGC_PDK1_PDPK1_ST	Q99683	MAP3K5	O15530	PDPK1	S980	E981D	981	Missense	proximal	1	no	1.524	3.759	EPSD	COSMIC	3.516	Gain
AGC_PDK1_PDPK1_ST	Q99683	MAP3K5	O15530	PDPK1	S986	G983S	983	Missense	distal	-3	no	2.950	3.820	EPSD	COSMIC;GDSC;CCLE	3.516	Gain
AGC_PDK1_PDPK1_ST	Q99683	MAP3K5	O15530	PDPK1	S997	K992I	992	Missense	distal	-5	no	6.969	7.155	EPSD	COSMIC	3.516	Up-regulation
AGC_PDK1_PDPK1_ST	Q99683	MAP3K5	O15530	PDPK1	S997	S1004F	1004	Missense	distal	7	no	6.969	6.683	EPSD	COSMIC	3.516	Down-regulation
AGC_PDK1_PDPK1_ST	Q99683	MAP3K5	O15530	PDPK1	S997	F998L	998	Missense	proximal	1	no	6.969	4.008	EPSD	COSMIC	3.516	Down-regulation
AGC_PDK1_PDPK1_ST	Q99683	MAP3K5	O15530	PDPK1	S997	E990D	990	Missense	distal	-7	no	6.969	7.058	EPSD	COSMIC	3.516	Up-regulation
AGC_PDK1_PDPK1_ST	Q99683	MAP3K5	O15530	PDPK1	S1033	P1032S	1032	Missense	proximal	-1	no	4.389	4.409	EPSD	COSMIC	3.516	Up-regulation
AGC_PDK1_PDPK1_ST	Q99683	MAP3K5	O15530	PDPK1	S1033	H1028Y	1028	Missense	distal	-5	no	4.389	4.533	EPSD	COSMIC	3.516	Up-regulation
AGC_PDK1_PDPK1_ST	Q99683	MAP3K5	O15530	PDPK1	S1033	D1027Y	1027	Missense	distal	-6	no	4.389	4.400	EPSD	COSMIC	3.516	Up-regulation
AGC_PDK1_PDPK1_ST	Q99683	MAP3K5	O15530	PDPK1	S1224	S1231T	1231	Missense	distal	7	no	4.607	4.564	EPSD	COSMIC	3.516	Down-regulation
AGC_PDK1_PDPK1_ST	Q99683	MAP3K5	O15530	PDPK1	S1227	S1231T	1231	Missense	distal	4	no	3.814	3.877	EPSD	COSMIC	3.516	Up-regulation
AGC_PDK1_PDPK1_ST	Q99683	MAP3K5	O15530	PDPK1	T1229	S1231T	1231	Missense	proximal	2	no	3.549	3.528	EPSD	COSMIC	3.516	Down-regulation
AGC_PDK1_PDPK1_ST	Q16513	PKN2	O15530	PDPK1	S310	T314A	314	Missense	distal	4	no	3.792	3.303	EPSD	COSMIC	3.516	Loss
AGC_PDK1_PDPK1_ST	Q16513	PKN2	O15530	PDPK1	T533	S535G	535	Missense	proximal	2	no	5.008	4.952	EPSD	COSMIC	3.516	Down-regulation
AGC_PDK1_PDPK1_ST	Q16513	PKN2	O15530	PDPK1	T533	P526H	526	Missense	distal	-7	no	5.008	4.638	EPSD	COSMIC	3.516	Down-regulation
AGC_PDK1_PDPK1_ST	Q16513	PKN2	O15530	PDPK1	S535	S535G	535	Missense	central	0	yes	3.966	0.000	EPSD	COSMIC	3.516	Loss
AGC_PDK1_PDPK1_ST	Q16513	PKN2	O15530	PDPK1	S535	T542P	542	Missense	distal	7	no	3.966	4.170	EPSD	COSMIC	3.516	Up-regulation
AGC_PDK1_PDPK1_ST	Q16513	PKN2	O15530	PDPK1	S535	P539S	539	Missense	distal	4	no	3.966	4.107	EPSD	COSMIC	3.516	Up-regulation
AGC_PDK1_PDPK1_ST	Q16513	PKN2	O15530	PDPK1	S815	S815N	815	Missense	central	0	yes	4.251	0.000	EPSD	COSMIC	3.516	Loss
AGC_PDK1_PDPK1_ST	Q16513	PKN2	O15530	PDPK1	S815	E822D	822	Missense	distal	7	no	4.251	4.250	EPSD	COSMIC	3.516	Down-regulation
AGC_PDK1_PDPK1_ST	Q16513	PKN2	O15530	PDPK1	S815	F817I	817	Missense	proximal	2	no	4.251	4.266	EPSD	COSMIC	3.516	Up-regulation
AGC_PDK1_PDPK1_ST	Q16513	PKN2	O15530	PDPK1	T816	S815N	815	Missense	proximal	-1	no	9.644	9.652	PhosphoSitePlus	COSMIC	3.516	Up-regulation
AGC_PDK1_PDPK1_ST	Q16513	PKN2	O15530	PDPK1	T816	F817I	817	Missense	proximal	1	no	9.644	3.429	PhosphoSitePlus	COSMIC	3.516	Loss
AGC_PDK1_PDPK1_ST	Q16513	PKN2	O15530	PDPK1	T958	I956F	956	Missense	proximal	-2	no	6.082	6.045	EPSD	COSMIC	3.516	Down-regulation
AGC_PDK1_PDPK1_ST	Q16513	PKN2	O15530	PDPK1	T958	P955A	955	Missense	distal	-3	no	6.082	5.784	EPSD	COSMIC	3.516	Down-regulation
AGC_PDK1_PDPK1_ST	Q16513	PKN2	O15530	PDPK1	T958	R964K	964	Missense	distal	6	no	6.082	6.083	EPSD	COSMIC	3.516	Up-regulation
AGC_PDK1_PDPK1_ST	Q02156	PRKCE	O15530	PDPK1	S329	P330S	330	Missense	proximal	1	no	5.133	2.338	EPSD	COSMIC	3.516	Loss
AGC_PDK1_PDPK1_ST	Q02156	PRKCE	O15530	PDPK1	S337	P330S	330	Missense	distal	-7	no	6.709	6.684	EPSD	COSMIC	3.516	Down-regulation
AGC_PDK1_PDPK1_ST	Q02156	PRKCE	O15530	PDPK1	S368	N361T	361	Missense	distal	-7	no	4.738	4.969	EPSD	COSMIC	3.516	Up-regulation
AGC_PDK1_PDPK1_ST	Q02156	PRKCE	O15530	PDPK1	S368	R372Q	372	Missense	distal	4	no	4.738	4.236	EPSD	COSMIC	3.516	Down-regulation
AGC_PDK1_PDPK1_ST	Q02156	PRKCE	O15530	PDPK1	S388	P389T	389	Missense	proximal	1	no	4.817	1.850	EPSD	COSMIC	3.516	Loss
STE_STE11_ASK_MAP3K5_ST	Q9UER7	DAXX	Q99683	MAP3K5	S53	S53L	53	Missense	central	0	yes	27.342	0.000	EPSD	COSMIC;GDSC;CCLE	22.468	Loss
STE_STE11_ASK_MAP3K5_ST	Q9UER7	DAXX	Q99683	MAP3K5	S53	R48K	48	Missense	distal	-5	no	27.342	27.236	EPSD	COSMIC	22.468	Down-regulation
STE_STE11_ASK_MAP3K5_ST	Q9UER7	DAXX	Q99683	MAP3K5	S53	S50N	50	Missense	distal	-3	no	27.342	26.046	EPSD	COSMIC	22.468	Down-regulation
STE_STE11_ASK_MAP3K5_ST	Q9UER7	DAXX	Q99683	MAP3K5	S53	R48T	48	Missense	distal	-5	no	27.342	26.713	EPSD	COSMIC	22.468	Down-regulation
STE_STE11_ASK_MAP3K5_ST	Q9UER7	DAXX	Q99683	MAP3K5	S53	G49R	49	Missense	distal	-4	no	27.342	27.913	EPSD	COSMIC	22.468	Up-regulation
STE_STE11_ASK_MAP3K5_ST	Q9UER7	DAXX	Q99683	MAP3K5	S53	K60M	60	Missense	distal	7	no	27.342	26.939	EPSD	COSMIC	22.468	Down-regulation
STE_STE11_ASK_MAP3K5_ST	Q9UER7	DAXX	Q99683	MAP3K5	S53	G54C	54	Missense	proximal	1	no	27.342	26.755	EPSD	COSMIC	22.468	Down-regulation
STE_STE11_ASK_MAP3K5_ST	Q9UER7	DAXX	Q99683	MAP3K5	S53	G55D	55	Missense	proximal	2	no	27.342	28.454	EPSD	COSMIC	22.468	Up-regulation
STE_STE11_ASK_MAP3K5_ST	Q9UER7	DAXX	Q99683	MAP3K5	S165	L164P	164	Missense	proximal	-1	no	24.658	24.007	EPSD	COSMIC	22.468	Down-regulation
STE_STE11_ASK_MAP3K5_ST	Q9UER7	DAXX	Q99683	MAP3K5	S165	S165F	165	Missense	central	0	yes	24.658	0.000	EPSD	COSMIC	22.468	Loss
STE_STE11_ASK_MAP3K5_ST	Q9UER7	DAXX	Q99683	MAP3K5	S165	P168H	168	Missense	distal	3	no	24.658	24.668	EPSD	COSMIC	22.468	Up-regulation
STE_STE11_ASK_MAP3K5_ST	Q9UER7	DAXX	Q99683	MAP3K5	S165	T162P	162	Missense	distal	-3	no	24.658	24.191	EPSD	COSMIC	22.468	Down-regulation
STE_STE11_ASK_MAP3K5_ST	Q9UER7	DAXX	Q99683	MAP3K5	S165	H163Q	163	Missense	proximal	-2	no	24.658	25.003	EPSD	COSMIC	22.468	Up-regulation
STE_STE11_ASK_MAP3K5_ST	Q9UER7	DAXX	Q99683	MAP3K5	S176	Q177E	177	Missense	proximal	1	no	39.634	43.038	PhosphoSitePlus;EPSD	COSMIC	22.468	Up-regulation
STE_STE11_ASK_MAP3K5_ST	Q9UER7	DAXX	Q99683	MAP3K5	S184	R185C	185	Missense	proximal	1	no	37.891	39.944	EPSD;PhosphoSitePlus	COSMIC	22.468	Up-regulation
STE_STE11_ASK_MAP3K5_ST	Q9UER7	DAXX	Q99683	MAP3K5	S184	Q177E	177	Missense	distal	-7	no	37.891	37.669	EPSD;PhosphoSitePlus	COSMIC	22.468	Down-regulation
STE_STE11_ASK_MAP3K5_ST	Q9UER7	DAXX	Q99683	MAP3K5	T401	R397Q	397	Missense	distal	-4	no	21.642	22.665	EPSD	COSMIC	22.468	Gain
STE_STE11_ASK_MAP3K5_ST	Q9UER7	DAXX	Q99683	MAP3K5	S431	S429F	429	Missense	proximal	-2	no	27.260	26.694	EPSD	COSMIC	22.468	Down-regulation
STE_STE11_ASK_MAP3K5_ST	Q9UER7	DAXX	Q99683	MAP3K5	S499	P496T	496	Missense	distal	-3	no	22.099	22.566	EPSD	COSMIC	22.468	Gain
STE_STE11_ASK_MAP3K5_ST	Q9UER7	DAXX	Q99683	MAP3K5	S499	P496L	496	Missense	distal	-3	no	22.099	23.018	EPSD	COSMIC	22.468	Gain
STE_STE11_ASK_MAP3K5_ST	Q9UER7	DAXX	Q99683	MAP3K5	S647	P643S	643	Missense	distal	-4	no	23.166	23.270	EPSD	COSMIC	22.468	Up-regulation
STE_STE11_ASK_MAP3K5_ST	Q9UER7	DAXX	Q99683	MAP3K5	S647	S647R	647	Missense	central	0	yes	23.166	0.000	EPSD	COSMIC	22.468	Loss
STE_STE11_ASK_MAP3K5_ST	Q9UER7	DAXX	Q99683	MAP3K5	T684	A677V	677	Missense	distal	-7	no	24.662	24.808	EPSD	COSMIC	22.468	Up-regulation
STE_STE11_ASK_MAP3K5_ST	Q9UER7	DAXX	Q99683	MAP3K5	T684	S688C	688	Missense	distal	4	no	24.662	21.908	EPSD	COSMIC	22.468	Loss
STE_STE11_ASK_MAP3K5_ST	Q9UER7	DAXX	Q99683	MAP3K5	T684	S682F	682	Missense	proximal	-2	no	24.662	24.095	EPSD	COSMIC	22.468	Down-regulation
STE_STE11_ASK_MAP3K5_ST	P46734	MAP2K3	Q99683	MAP3K5	T39	P40T	40	Missense	proximal	1	no	25.039	21.607	EPSD	COSMIC	22.468	Loss
STE_STE11_ASK_MAP3K5_ST	P46734	MAP2K3	Q99683	MAP3K5	T39	T39I	39	Missense	central	0	yes	25.039	0.000	EPSD	COSMIC;GDSC	22.468	Loss
STE_STE11_ASK_MAP3K5_ST	P46734	MAP2K3	Q99683	MAP3K5	T39	N43S	43	Missense	distal	4	no	25.039	25.764	EPSD	COSMIC	22.468	Up-regulation
STE_STE11_ASK_MAP3K5_ST	P46734	MAP2K3	Q99683	MAP3K5	T39	P33Q	33	Missense	distal	-6	no	25.039	24.866	EPSD	COSMIC;GDSC;CCLE	22.468	Down-regulation
STE_STE11_ASK_MAP3K5_ST	P46734	MAP2K3	Q99683	MAP3K5	T39	P36H	36	Missense	distal	-3	no	25.039	26.964	EPSD	COSMIC	22.468	Up-regulation
STE_STE11_ASK_MAP3K5_ST	P46734	MAP2K3	Q99683	MAP3K5	T39	P41H	41	Missense	proximal	2	no	25.039	25.020	EPSD	COSMIC	22.468	Down-regulation
STE_STE11_ASK_MAP3K5_ST	P46734	MAP2K3	Q99683	MAP3K5	T39	N37S	37	Missense	proximal	-2	no	25.039	24.931	EPSD	COSMIC	22.468	Down-regulation
STE_STE11_ASK_MAP3K5_ST	P46734	MAP2K3	Q99683	MAP3K5	T39	P36T	36	Missense	distal	-3	no	25.039	25.506	EPSD	COSMIC	22.468	Up-regulation
STE_STE11_ASK_MAP3K5_ST	P46734	MAP2K3	Q99683	MAP3K5	T39	S46F	46	Missense	distal	7	no	25.039	25.281	EPSD	COSMIC	22.468	Up-regulation
STE_STE11_ASK_MAP3K5_ST	P46734	MAP2K3	Q99683	MAP3K5	T39	A35T	35	Missense	distal	-4	no	25.039	24.984	EPSD	COSMIC	22.468	Down-regulation
STE_STE11_ASK_MAP3K5_ST	P46734	MAP2K3	Q99683	MAP3K5	T39	K32R	32	Missense	distal	-7	no	25.039	25.175	EPSD	COSMIC	22.468	Up-regulation
STE_STE11_ASK_MAP3K5_ST	P46734	MAP2K3	Q99683	MAP3K5	T39	P36L	36	Missense	distal	-3	no	25.039	25.959	EPSD	COSMIC;CCLE	22.468	Up-regulation
STE_STE11_ASK_MAP3K5_ST	P46734	MAP2K3	Q99683	MAP3K5	T117	L111M	111	Missense	distal	-6	no	29.389	29.206	EPSD	COSMIC;GDSC;CCLE	22.468	Down-regulation
STE_STE11_ASK_MAP3K5_ST	P46734	MAP2K3	Q99683	MAP3K5	T117	V124A	124	Missense	distal	7	no	29.389	29.072	EPSD	COSMIC	22.468	Down-regulation
STE_STE11_ASK_MAP3K5_ST	P46734	MAP2K3	Q99683	MAP3K5	T117	M115I	115	Missense	proximal	-2	no	29.389	29.169	EPSD	COSMIC	22.468	Down-regulation
STE_STE11_ASK_MAP3K5_ST	P46734	MAP2K3	Q99683	MAP3K5	S218	L215W	215	Missense	distal	-3	no	44.183	45.940	PhosphoSitePlus	COSMIC	22.468	Up-regulation
STE_STE11_ASK_MAP3K5_ST	P46734	MAP2K3	Q99683	MAP3K5	S218	T222M	222	Missense	distal	4	no	44.183	43.020	PhosphoSitePlus	COSMIC	22.468	Down-regulation
STE_STE11_ASK_MAP3K5_ST	P46734	MAP2K3	Q99683	MAP3K5	S218	L215V	215	Missense	distal	-3	no	44.183	46.405	PhosphoSitePlus	COSMIC;GDSC;CCLE	22.468	Up-regulation
STE_STE11_ASK_MAP3K5_ST	P46734	MAP2K3	Q99683	MAP3K5	T222	L215W	215	Missense	distal	-7	no	33.198	34.156	EPSD	COSMIC	22.468	Up-regulation
STE_STE11_ASK_MAP3K5_ST	P46734	MAP2K3	Q99683	MAP3K5	T222	T222M	222	Missense	central	0	yes	33.198	0.000	EPSD	COSMIC	22.468	Loss
STE_STE11_ASK_MAP3K5_ST	P46734	MAP2K3	Q99683	MAP3K5	T222	K228Q	228	Missense	distal	6	no	33.198	32.901	EPSD	COSMIC	22.468	Down-regulation
STE_STE11_ASK_MAP3K5_ST	P46734	MAP2K3	Q99683	MAP3K5	T222	G226D	226	Missense	distal	4	no	33.198	35.526	EPSD	COSMIC;GDSC;CCLE	22.468	Up-regulation
STE_STE11_ASK_MAP3K5_ST	P46734	MAP2K3	Q99683	MAP3K5	T222	P229H	229	Missense	distal	7	no	33.198	33.014	EPSD	COSMIC;GDSC;CCLE	22.468	Down-regulation
STE_STE11_ASK_MAP3K5_ST	P46734	MAP2K3	Q99683	MAP3K5	T222	G226S	226	Missense	distal	4	no	33.198	37.496	EPSD	COSMIC;GDSC	22.468	Up-regulation
STE_STE11_ASK_MAP3K5_ST	P46734	MAP2K3	Q99683	MAP3K5	T222	L215V	215	Missense	distal	-7	no	33.198	33.188	EPSD	COSMIC;GDSC;CCLE	22.468	Down-regulation
STE_STE11_ASK_MAP3K5_ST	P45983	MAPK8	Q99683	MAP3K5	S179	G177R	177	Missense	proximal	-2	no	29.048	29.451	EPSD	COSMIC	22.468	Up-regulation
STE_STE11_ASK_MAP3K5_ST	P45983	MAPK8	Q99683	MAP3K5	S179	G177K	177	Missense	proximal	-2	no	29.048	29.142	EPSD	COSMIC	22.468	Up-regulation
STE_STE11_ASK_MAP3K5_ST	P45983	MAPK8	Q99683	MAP3K5	S179	T183A	183	Missense	distal	4	no	29.048	27.872	EPSD	COSMIC	22.468	Down-regulation
STE_STE11_ASK_MAP3K5_ST	P45983	MAPK8	Q99683	MAP3K5	T183	G177R	177	Missense	distal	-6	no	46.269	46.382	PhosphoSitePlus;EPSD	COSMIC	22.468	Up-regulation
STE_STE11_ASK_MAP3K5_ST	P45983	MAPK8	Q99683	MAP3K5	T183	R189G	189	Missense	distal	6	no	46.269	40.912	PhosphoSitePlus;EPSD	COSMIC	22.468	Down-regulation
STE_STE11_ASK_MAP3K5_ST	P45983	MAPK8	Q99683	MAP3K5	T183	G177K	177	Missense	distal	-6	no	46.269	46.277	PhosphoSitePlus;EPSD	COSMIC	22.468	Up-regulation
STE_STE11_ASK_MAP3K5_ST	P45983	MAPK8	Q99683	MAP3K5	T183	T183A	183	Missense	central	0	yes	46.269	0.000	PhosphoSitePlus;EPSD	COSMIC	22.468	Loss
STE_STE11_ASK_MAP3K5_ST	P52564	MAP2K6	Q99683	MAP3K5	S207	D213Y	213	Missense	distal	6	no	42.328	35.732	PhosphoSitePlus	COSMIC	22.468	Down-regulation
STE_STE11_ASK_MAP3K5_ST	P52564	MAP2K6	Q99683	MAP3K5	T211	D213Y	213	Missense	proximal	2	no	29.569	32.510	EPSD	COSMIC	22.468	Up-regulation
STE_STE11_ASK_MAP3K5_ST	Q99683	MAP3K5	Q99683	MAP3K5	S267	L260F	260	Missense	distal	-7	no	35.185	35.405	EPSD	COSMIC	22.468	Up-regulation
STE_STE11_ASK_MAP3K5_ST	Q99683	MAP3K5	Q99683	MAP3K5	S267	R273L	273	Missense	distal	6	no	35.185	32.144	EPSD	COSMIC	22.468	Down-regulation
STE_STE11_ASK_MAP3K5_ST	Q99683	MAP3K5	Q99683	MAP3K5	S267	A264S	264	Missense	distal	-3	no	35.185	33.723	EPSD	COSMIC	22.468	Down-regulation
STE_STE11_ASK_MAP3K5_ST	Q99683	MAP3K5	Q99683	MAP3K5	S267	K262M	262	Missense	distal	-5	no	35.185	34.476	EPSD	COSMIC	22.468	Down-regulation
STE_STE11_ASK_MAP3K5_ST	Q99683	MAP3K5	Q99683	MAP3K5	S269	R273L	273	Missense	distal	4	no	26.107	25.507	EPSD	COSMIC	22.468	Down-regulation
STE_STE11_ASK_MAP3K5_ST	Q99683	MAP3K5	Q99683	MAP3K5	S269	A264S	264	Missense	distal	-5	no	26.107	26.879	EPSD	COSMIC	22.468	Up-regulation
STE_STE11_ASK_MAP3K5_ST	Q99683	MAP3K5	Q99683	MAP3K5	S269	K262M	262	Missense	distal	-7	no	26.107	26.065	EPSD	COSMIC	22.468	Down-regulation
STE_STE11_ASK_MAP3K5_ST	Q99683	MAP3K5	Q99683	MAP3K5	S719	Q720E	720	Missense	proximal	1	no	19.971	23.375	EPSD	COSMIC	22.468	Gain
STE_STE11_ASK_MAP3K5_ST	Q99683	MAP3K5	Q99683	MAP3K5	T813	N812I	812	Missense	proximal	-1	no	38.041	40.219	EPSD;PhosphoSitePlus	COSMIC	22.468	Up-regulation
STE_STE11_ASK_MAP3K5_ST	Q99683	MAP3K5	Q99683	MAP3K5	T813	T813I	813	Missense	central	0	yes	38.041	0.000	EPSD;PhosphoSitePlus	COSMIC	22.468	Loss
STE_STE11_ASK_MAP3K5_ST	Q99683	MAP3K5	Q99683	MAP3K5	T813	D807G	807	Missense	distal	-6	no	38.041	38.094	EPSD;PhosphoSitePlus	COSMIC	22.468	Up-regulation
STE_STE11_ASK_MAP3K5_ST	Q99683	MAP3K5	Q99683	MAP3K5	T813	G806S	806	Missense	distal	-7	no	38.041	36.466	EPSD;PhosphoSitePlus	COSMIC	22.468	Down-regulation
STE_STE11_ASK_MAP3K5_ST	Q99683	MAP3K5	Q99683	MAP3K5	T838	P834S	834	Missense	distal	-4	no	40.805	40.909	PhosphoSitePlus;EPSD	COSMIC	22.468	Up-regulation
STE_STE11_ASK_MAP3K5_ST	Q99683	MAP3K5	Q99683	MAP3K5	T838	I832T	832	Missense	distal	-6	no	40.805	40.817	PhosphoSitePlus;EPSD	COSMIC;GDSC;CCLE	22.468	Up-regulation
STE_STE11_ASK_MAP3K5_ST	Q99683	MAP3K5	Q99683	MAP3K5	T838	G841C	841	Missense	distal	3	no	40.805	41.042	PhosphoSitePlus;EPSD	COSMIC	22.468	Up-regulation
STE_STE11_ASK_MAP3K5_ST	Q99683	MAP3K5	Q99683	MAP3K5	T842	G841C	841	Missense	proximal	-1	no	36.339	36.698	EPSD;PhosphoSitePlus	COSMIC	22.468	Up-regulation
STE_STE11_ASK_MAP3K5_ST	Q99683	MAP3K5	Q99683	MAP3K5	S964	G957E	957	Missense	distal	-7	no	31.722	31.262	EPSD	COSMIC	22.468	Down-regulation
STE_STE11_ASK_MAP3K5_ST	Q99683	MAP3K5	Q99683	MAP3K5	S964	V969I	969	Missense	distal	5	no	31.722	31.436	EPSD	COSMIC	22.468	Down-regulation
STE_STE11_ASK_MAP3K5_ST	Q99683	MAP3K5	Q99683	MAP3K5	S966	V969I	969	Missense	distal	3	no	35.671	34.391	EPSD;PhosphoSitePlus	COSMIC	22.468	Down-regulation
STE_STE11_ASK_MAP3K5_ST	Q99683	MAP3K5	Q99683	MAP3K5	S978	G983C	983	Missense	distal	5	no	28.153	28.867	EPSD	COSMIC	22.468	Up-regulation
STE_STE11_ASK_MAP3K5_ST	Q99683	MAP3K5	Q99683	MAP3K5	S978	E981D	981	Missense	distal	3	no	28.153	29.542	EPSD	COSMIC	22.468	Up-regulation
STE_STE11_ASK_MAP3K5_ST	Q99683	MAP3K5	Q99683	MAP3K5	S978	G983S	983	Missense	distal	5	no	28.153	30.451	EPSD	COSMIC;GDSC;CCLE	22.468	Up-regulation
STE_STE11_ASK_MAP3K5_ST	Q99683	MAP3K5	Q99683	MAP3K5	T1015	G1012R	1012	Missense	distal	-3	no	27.659	26.249	EPSD	COSMIC	22.468	Down-regulation
STE_STE11_ASK_MAP3K5_ST	Q99683	MAP3K5	Q99683	MAP3K5	T1015	R1008T	1008	Missense	distal	-7	no	27.659	28.250	EPSD	COSMIC	22.468	Up-regulation
STE_STE11_ASK_MAP3K5_ST	Q99683	MAP3K5	Q99683	MAP3K5	T1015	V1010A	1010	Missense	distal	-5	no	27.659	28.107	EPSD	COSMIC	22.468	Up-regulation
STE_STE11_ASK_MAP3K5_ST	Q99683	MAP3K5	Q99683	MAP3K5	T1015	I1013T	1013	Missense	proximal	-2	no	27.659	27.983	EPSD	COSMIC	22.468	Up-regulation
STE_STE11_ASK_MAP3K5_ST	Q99683	MAP3K5	Q99683	MAP3K5	S1039	P1032S	1032	Missense	distal	-7	no	23.848	22.199	EPSD	COSMIC	22.468	Loss
STE_STE11_ASK_MAP3K5_ST	Q99683	MAP3K5	Q99683	MAP3K5	S1039	S1039Y	1039	Missense	central	0	yes	23.848	0.000	EPSD	COSMIC	22.468	Loss
STE_STE11_ASK_MAP3K5_ST	Q99683	MAP3K5	Q99683	MAP3K5	T1229	S1231T	1231	Missense	proximal	2	no	23.304	20.214	EPSD	COSMIC	22.468	Loss
STE_STE11_ASK_MAP3K5_ST	Q9Y3F4	STRAP	Q99683	MAP3K5	T175	S179Y	179	Missense	distal	4	no	35.430	33.328	PhosphoSitePlus;EPSD	COSMIC	22.468	Down-regulation
STE_STE11_ASK_MAP3K5_ST	Q9Y3F4	STRAP	Q99683	MAP3K5	T175	K178R	178	Missense	distal	3	no	35.430	35.356	PhosphoSitePlus;EPSD	COSMIC	22.468	Down-regulation
STE_STE11_ASK_MAP3K5_ST	Q9Y3F4	STRAP	Q99683	MAP3K5	T175	W169L	169	Missense	distal	-6	no	35.430	35.346	PhosphoSitePlus;EPSD	COSMIC	22.468	Down-regulation
STE_STE11_ASK_MAP3K5_ST	Q9Y3F4	STRAP	Q99683	MAP3K5	S179	S179Y	179	Missense	central	0	yes	42.363	0.000	EPSD;PhosphoSitePlus	COSMIC	22.468	Loss
STE_STE11_ASK_MAP3K5_ST	Q9Y3F4	STRAP	Q99683	MAP3K5	S179	K178R	178	Missense	proximal	-1	no	42.363	41.889	EPSD;PhosphoSitePlus	COSMIC	22.468	Down-regulation
STE_STE11_ASK_MAP3K5_ST	Q9Y3F4	STRAP	Q99683	MAP3K5	S254	G255E	255	Missense	proximal	1	no	26.920	27.182	EPSD	COSMIC	22.468	Up-regulation
STE_STE11_ASK_MAP3K5_ST	Q9Y3F4	STRAP	Q99683	MAP3K5	S254	G255S	255	Missense	proximal	1	no	26.920	22.791	EPSD	COSMIC	22.468	Down-regulation
STE_STE11_ASK_MAP3K5_ST	Q9Y3F4	STRAP	Q99683	MAP3K5	S312	L315P	315	Missense	distal	3	no	26.412	25.909	EPSD	COSMIC	22.468	Down-regulation
STE_STE11_ASK_MAP3K5_ST	Q16539	MAPK14	Q99683	MAP3K5	T180	T185I	185	Missense	distal	5	no	42.356	41.942	PhosphoSitePlus;EPSD	COSMIC	22.468	Down-regulation
STE_STE11_ASK_MAP3K5_ST	Q969S3	ZNF622	Q99683	MAP3K5	S286	E283G	283	Missense	distal	-3	no	24.391	23.095	EPSD	COSMIC	22.468	Down-regulation
STE_STE11_ASK_MAP3K5_ST	Q969S3	ZNF622	Q99683	MAP3K5	S286	P280S	280	Missense	distal	-6	no	24.391	23.970	EPSD	COSMIC	22.468	Down-regulation
STE_STE11_ASK_MAP3K5_ST	Q969S3	ZNF622	Q99683	MAP3K5	S314	S317P	317	Missense	distal	3	no	39.848	42.695	EPSD;PhosphoSitePlus	COSMIC	22.468	Up-regulation
STE_STE11_ASK_MAP3K5_ST	Q969S3	ZNF622	Q99683	MAP3K5	S314	G312L	312	Missense	proximal	-2	no	39.848	40.020	EPSD;PhosphoSitePlus	COSMIC	22.468	Up-regulation
STE_STE11_ASK_MAP3K5_ST	Q969S3	ZNF622	Q99683	MAP3K5	T318	S317P	317	Missense	proximal	-1	no	38.038	38.253	PhosphoSitePlus;EPSD	COSMIC	22.468	Up-regulation
STE_STE11_ASK_MAP3K5_ST	Q969S3	ZNF622	Q99683	MAP3K5	T318	G312L	312	Missense	distal	-6	no	38.038	38.216	PhosphoSitePlus;EPSD	COSMIC	22.468	Up-regulation
STE_STE11_ASK_MAP3K5_ST	Q15691	MAPRE1	Q99683	MAP3K5	T154	P160H	160	Missense	distal	6	no	35.846	31.939	EPSD;PhosphoSitePlus	COSMIC	22.468	Down-regulation
STE_STE11_ASK_MAP3K5_ST	Q15691	MAPRE1	Q99683	MAP3K5	T206	K212N	212	Missense	distal	6	no	41.243	43.262	PhosphoSitePlus;EPSD	COSMIC	22.468	Up-regulation
STE_STE11_ASK_MAP3K5_ST	O15530	PDPK1	Q99683	MAP3K5	S344	L350F	350	Missense	distal	6	no	25.009	22.830	EPSD	COSMIC	22.468	Down-regulation
STE_STE11_ASK_MAP3K5_ST	O15530	PDPK1	Q99683	MAP3K5	S344	H339P	339	Missense	distal	-5	no	25.009	25.827	EPSD	COSMIC	22.468	Up-regulation
STE_STE11_ASK_MAP3K5_ST	O15530	PDPK1	Q99683	MAP3K5	T346	L350F	350	Missense	distal	4	no	24.014	23.532	EPSD	COSMIC	22.468	Down-regulation
STE_STE11_ASK_MAP3K5_ST	O15530	PDPK1	Q99683	MAP3K5	T346	H339P	339	Missense	distal	-7	no	24.014	24.439	EPSD	COSMIC	22.468	Up-regulation
STE_STE11_ASK_MAP3K5_ST	O15530	PDPK1	Q99683	MAP3K5	S394	S396F	396	Missense	proximal	2	no	42.051	33.068	EPSD;PhosphoSitePlus	COSMIC	22.468	Down-regulation
STE_STE11_ASK_MAP3K5_ST	O15530	PDPK1	Q99683	MAP3K5	S394	S398L	398	Missense	distal	4	no	42.051	40.882	EPSD;PhosphoSitePlus	COSMIC	22.468	Down-regulation
STE_STE11_ASK_MAP3K5_ST	O15530	PDPK1	Q99683	MAP3K5	S394	Q387R	387	Missense	distal	-7	no	42.051	41.456	EPSD;PhosphoSitePlus	COSMIC	22.468	Down-regulation
STE_STE11_ASK_MAP3K5_ST	O15530	PDPK1	Q99683	MAP3K5	S394	S394L	394	Missense	central	0	yes	42.051	0.000	EPSD;PhosphoSitePlus	COSMIC	22.468	Loss
STE_STE11_ASK_MAP3K5_ST	O15530	PDPK1	Q99683	MAP3K5	S394	Q387H	387	Missense	distal	-7	no	42.051	41.937	EPSD;PhosphoSitePlus	COSMIC;CCLE	22.468	Down-regulation
STE_STE11_ASK_MAP3K5_ST	O15530	PDPK1	Q99683	MAP3K5	S396	S396F	396	Missense	central	0	yes	25.082	0.000	EPSD	COSMIC	22.468	Loss
STE_STE11_ASK_MAP3K5_ST	O15530	PDPK1	Q99683	MAP3K5	S396	G403W	403	Missense	distal	7	no	25.082	25.072	EPSD	COSMIC	22.468	Down-regulation
STE_STE11_ASK_MAP3K5_ST	O15530	PDPK1	Q99683	MAP3K5	S396	G403E	403	Missense	distal	7	no	25.082	24.669	EPSD	COSMIC	22.468	Down-regulation
STE_STE11_ASK_MAP3K5_ST	O15530	PDPK1	Q99683	MAP3K5	S396	S398L	398	Missense	proximal	2	no	25.082	16.601	EPSD	COSMIC	22.468	Loss
STE_STE11_ASK_MAP3K5_ST	O15530	PDPK1	Q99683	MAP3K5	S396	G403S	403	Missense	distal	7	no	25.082	24.732	EPSD	COSMIC	22.468	Down-regulation
STE_STE11_ASK_MAP3K5_ST	O15530	PDPK1	Q99683	MAP3K5	S396	S394L	394	Missense	proximal	-2	no	25.082	24.154	EPSD	COSMIC	22.468	Down-regulation
STE_STE11_ASK_MAP3K5_ST	O15530	PDPK1	Q99683	MAP3K5	S398	S396F	396	Missense	proximal	-2	no	40.770	40.203	PhosphoSitePlus;EPSD	COSMIC	22.468	Down-regulation
STE_STE11_ASK_MAP3K5_ST	O15530	PDPK1	Q99683	MAP3K5	S398	G403W	403	Missense	distal	5	no	40.770	40.599	PhosphoSitePlus;EPSD	COSMIC	22.468	Down-regulation
STE_STE11_ASK_MAP3K5_ST	O15530	PDPK1	Q99683	MAP3K5	S398	G403E	403	Missense	distal	5	no	40.770	41.573	PhosphoSitePlus;EPSD	COSMIC	22.468	Up-regulation
STE_STE11_ASK_MAP3K5_ST	O15530	PDPK1	Q99683	MAP3K5	S398	S398L	398	Missense	central	0	yes	40.770	0.000	PhosphoSitePlus;EPSD	COSMIC	22.468	Loss
STE_STE11_ASK_MAP3K5_ST	O15530	PDPK1	Q99683	MAP3K5	S398	G403S	403	Missense	distal	5	no	40.770	43.068	PhosphoSitePlus;EPSD	COSMIC	22.468	Up-regulation
STE_STE11_ASK_MAP3K5_ST	O15530	PDPK1	Q99683	MAP3K5	S398	S394L	394	Missense	distal	-4	no	40.770	38.475	PhosphoSitePlus;EPSD	COSMIC	22.468	Down-regulation
STE_STE11_ASK_MAP3K5_ST	P38936	CDKN1A	Q99683	MAP3K5	S98	T97I	97	Missense	proximal	-1	no	39.225	39.712	PhosphoSitePlus	COSMIC	22.468	Up-regulation
STE_STE11_ASK_MAP3K5_ST	P38936	CDKN1A	Q99683	MAP3K5	S160	R156W	156	Missense	distal	-4	no	24.134	23.055	EPSD	COSMIC;GDSC;CCLE	22.468	Down-regulation
STE_STE11_ASK_MAP3K5_ST	P38936	CDKN1A	Q99683	MAP3K5	S160	I158M	158	Missense	proximal	-2	no	24.134	24.353	EPSD	COSMIC	22.468	Up-regulation
STE_STE11_ASK_MAP3K5_ST	P38936	CDKN1A	Q99683	MAP3K5	S160	R155C	155	Missense	distal	-5	no	24.134	22.214	EPSD	COSMIC	22.468	Loss
STE_STE11_ASK_MAP3K5_ST	P45985	MAP2K4	Q99683	MAP3K5	S257	S251R	251	Missense	distal	-6	no	29.021	29.399	EPSD	COSMIC	22.468	Up-regulation
STE_STE11_ASK_MAP3K5_ST	P45985	MAP2K4	Q99683	MAP3K5	S257	T261R	261	Missense	distal	4	no	29.021	26.727	EPSD	COSMIC	22.468	Down-regulation
STE_STE11_ASK_MAP3K5_ST	P45985	MAP2K4	Q99683	MAP3K5	S257	S251N	251	Missense	distal	-6	no	29.021	28.901	EPSD	COSMIC;GDSC;CCLE	22.468	Down-regulation
STE_STE11_ASK_MAP3K5_ST	P45985	MAP2K4	Q99683	MAP3K5	S257	S257C	257	Missense	central	0	yes	29.021	0.000	EPSD	COSMIC	22.468	Loss
STE_STE11_ASK_MAP3K5_ST	P45985	MAP2K4	Q99683	MAP3K5	S257	D263Y	263	Missense	distal	6	no	29.021	22.425	EPSD	COSMIC	22.468	Loss
STE_STE11_ASK_MAP3K5_ST	P45985	MAP2K4	Q99683	MAP3K5	S257	S257Y	257	Missense	central	0	yes	29.021	0.000	EPSD	COSMIC	22.468	Loss
STE_STE11_ASK_MAP3K5_ST	P45985	MAP2K4	Q99683	MAP3K5	S257	G252R	252	Missense	distal	-5	no	29.021	30.550	EPSD	COSMIC	22.468	Up-regulation
STE_STE11_ASK_MAP3K5_ST	P45985	MAP2K4	Q99683	MAP3K5	S257	S251T	251	Missense	distal	-6	no	29.021	29.461	EPSD	COSMIC	22.468	Up-regulation
STE_STE11_ASK_MAP3K5_ST	P45985	MAP2K4	Q99683	MAP3K5	S257	L254R	254	Missense	distal	-3	no	29.021	29.263	EPSD	COSMIC;GDSC;CCLE	22.468	Up-regulation
STE_STE11_ASK_MAP3K5_ST	P45985	MAP2K4	Q99683	MAP3K5	S257	A259T	259	Missense	proximal	2	no	29.021	25.497	EPSD	COSMIC	22.468	Down-regulation
STE_STE11_ASK_MAP3K5_ST	P45985	MAP2K4	Q99683	MAP3K5	T261	T261R	261	Missense	central	0	yes	35.797	0.000	PhosphoSitePlus	COSMIC	22.468	Loss
STE_STE11_ASK_MAP3K5_ST	P45985	MAP2K4	Q99683	MAP3K5	T261	P268S	268	Missense	distal	7	no	35.797	35.397	PhosphoSitePlus	COSMIC	22.468	Down-regulation
STE_STE11_ASK_MAP3K5_ST	P45985	MAP2K4	Q99683	MAP3K5	T261	S257C	257	Missense	distal	-4	no	35.797	33.532	PhosphoSitePlus	COSMIC	22.468	Down-regulation
STE_STE11_ASK_MAP3K5_ST	P45985	MAP2K4	Q99683	MAP3K5	T261	D263Y	263	Missense	proximal	2	no	35.797	38.739	PhosphoSitePlus	COSMIC	22.468	Up-regulation
STE_STE11_ASK_MAP3K5_ST	P45985	MAP2K4	Q99683	MAP3K5	T261	S257T	257	Missense	distal	-4	no	35.797	35.747	PhosphoSitePlus	COSMIC	22.468	Down-regulation
STE_STE11_ASK_MAP3K5_ST	P45985	MAP2K4	Q99683	MAP3K5	T261	S257Y	257	Missense	distal	-4	no	35.797	34.588	PhosphoSitePlus	COSMIC	22.468	Down-regulation
STE_STE11_ASK_MAP3K5_ST	P45985	MAP2K4	Q99683	MAP3K5	T261	G265D	265	Missense	distal	4	no	35.797	38.125	PhosphoSitePlus	COSMIC;GDSC;CCLE	22.468	Up-regulation
STE_STE11_ASK_MAP3K5_ST	P45985	MAP2K4	Q99683	MAP3K5	T261	L254R	254	Missense	distal	-7	no	35.797	35.490	PhosphoSitePlus	COSMIC;GDSC;CCLE	22.468	Down-regulation
STE_STE11_ASK_MAP3K5_ST	P45985	MAP2K4	Q99683	MAP3K5	T261	R267M	267	Missense	distal	6	no	35.797	33.719	PhosphoSitePlus	COSMIC	22.468	Down-regulation
STE_STE11_ASK_MAP3K5_ST	P45985	MAP2K4	Q99683	MAP3K5	T261	A259T	259	Missense	proximal	-2	no	35.797	35.487	PhosphoSitePlus	COSMIC	22.468	Down-regulation
TK_VEGFR_KDR_Y	P35968	KDR	P35968	KDR	Y951	R946C	946	Missense	distal	-5	no	75.999	76.695	PhosphoSitePlus;EPSD	COSMIC	61.410	Up-regulation
TK_VEGFR_KDR_Y	P35968	KDR	P35968	KDR	Y951	G948R	948	Missense	distal	-3	no	75.999	76.776	PhosphoSitePlus;EPSD	COSMIC	61.410	Up-regulation
TK_VEGFR_KDR_Y	P35968	KDR	P35968	KDR	Y951	G948E	948	Missense	distal	-3	no	75.999	75.885	PhosphoSitePlus;EPSD	COSMIC	61.410	Down-regulation
TK_VEGFR_KDR_Y	P35968	KDR	P35968	KDR	Y951	G948W	948	Missense	distal	-3	no	75.999	65.704	PhosphoSitePlus;EPSD	COSMIC	61.410	Down-regulation
TK_VEGFR_KDR_Y	P35968	KDR	P35968	KDR	Y951	F945C	945	Missense	distal	-6	no	75.999	76.230	PhosphoSitePlus;EPSD	COSMIC	61.410	Up-regulation
TK_VEGFR_KDR_Y	P35968	KDR	P35968	KDR	Y951	A954V	954	Missense	distal	3	no	75.999	77.045	PhosphoSitePlus;EPSD	COSMIC	61.410	Up-regulation
TK_VEGFR_KDR_Y	P35968	KDR	P35968	KDR	Y951	R946S	946	Missense	distal	-5	no	75.999	75.541	PhosphoSitePlus;EPSD	COSMIC	61.410	Down-regulation
TK_VEGFR_KDR_Y	P35968	KDR	P35968	KDR	Y996	E990G	990	Missense	distal	-6	no	72.861	73.463	EPSD;PhosphoSitePlus	COSMIC	61.410	Up-regulation
TK_VEGFR_KDR_Y	P35968	KDR	P35968	KDR	Y996	E993K	993	Missense	distal	-3	no	72.861	80.839	EPSD;PhosphoSitePlus	COSMIC	61.410	Up-regulation
TK_VEGFR_KDR_Y	P35968	KDR	P35968	KDR	Y996	K997R	997	Missense	proximal	1	no	72.861	72.873	EPSD;PhosphoSitePlus	COSMIC	61.410	Up-regulation
TK_VEGFR_KDR_Y	P35968	KDR	P35968	KDR	Y1054	P1057S	1057	Missense	distal	3	no	66.935	66.775	EPSD;PhosphoSitePlus	COSMIC	61.410	Down-regulation
TK_VEGFR_KDR_Y	P35968	KDR	P35968	KDR	Y1054	R1051W	1051	Missense	distal	-3	no	66.935	55.863	EPSD;PhosphoSitePlus	COSMIC	61.410	Loss
TK_VEGFR_KDR_Y	P35968	KDR	P35968	KDR	Y1059	R1066H	1066	Missense	distal	7	no	66.389	62.199	EPSD;PhosphoSitePlus	COSMIC	61.410	Down-regulation
TK_VEGFR_KDR_Y	P35968	KDR	P35968	KDR	Y1059	P1057S	1057	Missense	proximal	-2	no	66.389	65.000	EPSD;PhosphoSitePlus	COSMIC	61.410	Down-regulation
TK_VEGFR_KDR_Y	P35968	KDR	P35968	KDR	Y1059	A1065T	1065	Missense	distal	6	no	66.389	65.096	EPSD;PhosphoSitePlus	COSMIC;GDSC	61.410	Down-regulation
TK_VEGFR_KDR_Y	P35968	KDR	P35968	KDR	Y1059	G1063R	1063	Missense	distal	4	no	66.389	66.346	EPSD;PhosphoSitePlus	COSMIC	61.410	Down-regulation
TK_VEGFR_KDR_Y	P35968	KDR	P35968	KDR	Y1059	D1064Y	1064	Missense	distal	5	no	66.389	66.270	EPSD;PhosphoSitePlus	COSMIC;GDSC;CCLE	61.410	Down-regulation
TK_VEGFR_KDR_Y	P35968	KDR	P35968	KDR	Y1175	D1174E	1174	Missense	proximal	-1	no	74.229	74.294	EPSD;PhosphoSitePlus	COSMIC	61.410	Up-regulation
TK_VEGFR_KDR_Y	P35968	KDR	P35968	KDR	Y1175	D1174N	1174	Missense	proximal	-1	no	74.229	74.331	EPSD;PhosphoSitePlus	COSMIC	61.410	Up-regulation
TK_VEGFR_KDR_Y	P35968	KDR	P35968	KDR	Y1175	G1172S	1172	Missense	distal	-3	no	74.229	79.696	EPSD;PhosphoSitePlus	COSMIC	61.410	Up-regulation
TK_VEGFR_KDR_Y	P35968	KDR	P35968	KDR	Y1175	A1168S	1168	Missense	distal	-7	no	74.229	71.403	EPSD;PhosphoSitePlus	COSMIC	61.410	Down-regulation
TK_VEGFR_KDR_Y	P35968	KDR	P35968	KDR	Y1175	A1168V	1168	Missense	distal	-7	no	74.229	77.506	EPSD;PhosphoSitePlus	COSMIC	61.410	Up-regulation
TK_VEGFR_KDR_Y	P35968	KDR	P35968	KDR	Y1175	E1182D	1182	Missense	distal	7	no	74.229	69.754	EPSD;PhosphoSitePlus	COSMIC	61.410	Down-regulation
TK_VEGFR_KDR_Y	P35968	KDR	P35968	KDR	Y1175	A1168D	1168	Missense	distal	-7	no	74.229	74.107	EPSD;PhosphoSitePlus	COSMIC	61.410	Down-regulation
TK_VEGFR_KDR_Y	P35968	KDR	P35968	KDR	Y1175	S1181L	1181	Missense	distal	6	no	74.229	73.857	EPSD;PhosphoSitePlus	COSMIC	61.410	Down-regulation
TK_VEGFR_KDR_Y	P35968	KDR	P35968	KDR	Y1175	D1171N	1171	Missense	distal	-4	no	74.229	74.169	EPSD;PhosphoSitePlus	COSMIC	61.410	Down-regulation
TK_VEGFR_KDR_Y	P35968	KDR	P35968	KDR	Y1214	P1210T	1210	Missense	distal	-4	no	92.464	92.448	EPSD;PhosphoSitePlus	COSMIC	61.410	Down-regulation
TK_VEGFR_KDR_Y	P35968	KDR	P35968	KDR	Y1214	C1208Y	1208	Missense	distal	-6	no	92.464	92.390	EPSD;PhosphoSitePlus	COSMIC	61.410	Down-regulation
TK_VEGFR_KDR_Y	P35968	KDR	P35968	KDR	Y1214	P1210L	1210	Missense	distal	-4	no	92.464	92.502	EPSD;PhosphoSitePlus	COSMIC	61.410	Up-regulation
TK_VEGFR_KDR_Y	P35968	KDR	P35968	KDR	Y1214	G1219V	1219	Missense	distal	5	no	92.464	90.314	EPSD;PhosphoSitePlus	COSMIC	61.410	Down-regulation
TK_VEGFR_KDR_Y	P35968	KDR	P35968	KDR	Y1214	G1219E	1219	Missense	distal	5	no	92.464	90.866	EPSD;PhosphoSitePlus	COSMIC	61.410	Down-regulation
TK_VEGFR_KDR_Y	P35968	KDR	P35968	KDR	Y1214	P1210H	1210	Missense	distal	-4	no	92.464	92.446	EPSD;PhosphoSitePlus	COSMIC	61.410	Down-regulation
TK_VEGFR_KDR_Y	P35968	KDR	P35968	KDR	Y1214	D1209N	1209	Missense	distal	-5	no	92.464	92.290	EPSD;PhosphoSitePlus	COSMIC	61.410	Down-regulation
TK_VEGFR_KDR_Y	P35968	KDR	P35968	KDR	Y1305	H1310Y	1310	Missense	distal	5	no	76.177	76.406	EPSD	COSMIC	61.410	Up-regulation
TK_VEGFR_KDR_Y	P35968	KDR	P35968	KDR	Y1305	S1311F	1311	Missense	distal	6	no	76.177	75.050	EPSD	COSMIC	61.410	Down-regulation
TK_VEGFR_KDR_Y	P35968	KDR	P35968	KDR	Y1305	G1304C	1304	Missense	proximal	-1	no	76.177	76.054	EPSD	COSMIC;GDSC;CCLE	61.410	Down-regulation
TK_VEGFR_KDR_Y	P35968	KDR	P35968	KDR	Y1305	Y1309D	1309	Missense	distal	4	no	76.177	76.026	EPSD	COSMIC	61.410	Down-regulation
TK_VEGFR_KDR_Y	P35968	KDR	P35968	KDR	Y1305	S1303N	1303	Missense	proximal	-2	no	76.177	72.954	EPSD	COSMIC;GDSC;CCLE	61.410	Down-regulation
TK_VEGFR_KDR_Y	P35968	KDR	P35968	KDR	Y1305	G1308R	1308	Missense	distal	3	no	76.177	76.080	EPSD	COSMIC	61.410	Down-regulation
TK_VEGFR_KDR_Y	P35968	KDR	P35968	KDR	Y1305	S1307F	1307	Missense	proximal	2	no	76.177	73.181	EPSD	COSMIC	61.410	Down-regulation
TK_VEGFR_KDR_Y	P35968	KDR	P35968	KDR	Y1305	S1303G	1303	Missense	proximal	-2	no	76.177	81.269	EPSD	COSMIC	61.410	Up-regulation
TK_VEGFR_KDR_Y	P35968	KDR	P35968	KDR	Y1309	H1310Y	1310	Missense	proximal	1	no	71.775	71.756	EPSD	COSMIC	61.410	Down-regulation
TK_VEGFR_KDR_Y	P35968	KDR	P35968	KDR	Y1309	S1311F	1311	Missense	proximal	2	no	71.775	68.780	EPSD	COSMIC	61.410	Down-regulation
TK_VEGFR_KDR_Y	P35968	KDR	P35968	KDR	Y1309	D1313N	1313	Missense	distal	4	no	71.775	71.451	EPSD	COSMIC	61.410	Down-regulation
TK_VEGFR_KDR_Y	P35968	KDR	P35968	KDR	Y1309	G1304C	1304	Missense	distal	-5	no	71.775	72.323	EPSD	COSMIC;GDSC;CCLE	61.410	Up-regulation
TK_VEGFR_KDR_Y	P35968	KDR	P35968	KDR	Y1309	T1316P	1316	Missense	distal	7	no	71.775	72.448	EPSD	COSMIC	61.410	Up-regulation
TK_VEGFR_KDR_Y	P35968	KDR	P35968	KDR	Y1309	Y1309D	1309	Missense	central	0	yes	71.775	0.000	EPSD	COSMIC	61.410	Loss
TK_VEGFR_KDR_Y	P35968	KDR	P35968	KDR	Y1309	S1303N	1303	Missense	distal	-6	no	71.775	70.418	EPSD	COSMIC;GDSC;CCLE	61.410	Down-regulation
TK_VEGFR_KDR_Y	P35968	KDR	P35968	KDR	Y1309	G1308R	1308	Missense	proximal	-1	no	71.775	71.745	EPSD	COSMIC	61.410	Down-regulation
TK_VEGFR_KDR_Y	P35968	KDR	P35968	KDR	Y1309	S1307F	1307	Missense	proximal	-2	no	71.775	70.644	EPSD	COSMIC	61.410	Down-regulation
TK_VEGFR_KDR_Y	P35968	KDR	P35968	KDR	Y1309	S1303G	1303	Missense	distal	-6	no	71.775	70.997	EPSD	COSMIC	61.410	Down-regulation
TK_VEGFR_KDR_Y	P35968	KDR	P35968	KDR	Y1319	D1313N	1313	Missense	distal	-6	no	75.004	73.327	EPSD	COSMIC	61.410	Down-regulation
TK_VEGFR_KDR_Y	P35968	KDR	P35968	KDR	Y1319	T1316P	1316	Missense	distal	-3	no	75.004	71.537	EPSD	COSMIC	61.410	Down-regulation
TK_VEGFR_KDR_Y	P35968	KDR	P35968	KDR	Y1319	V1318M	1318	Missense	proximal	-1	no	75.004	74.996	EPSD	COSMIC	61.410	Down-regulation
TK_VEGFR_KDR_Y	P35968	KDR	P35968	KDR	Y1319	E1322A	1322	Missense	distal	3	no	75.004	74.823	EPSD	COSMIC	61.410	Down-regulation
TK_VEGFR_KDR_Y	P35968	KDR	P35968	KDR	Y1319	E1325K	1325	Missense	distal	6	no	75.004	75.379	EPSD	COSMIC	61.410	Up-regulation
TK_VEGFR_KDR_Y	P35968	KDR	P35968	KDR	Y1319	E1323K	1323	Missense	distal	4	no	75.004	74.696	EPSD	COSMIC	61.410	Down-regulation
AGC_GRK_GRK_GRK5_ST	P07550	ADRB2	P34947	GRK5	S261	C265S	265	Missense	distal	4	no	2.394	2.388	EPSD	COSMIC	1.854	Down-regulation
AGC_GRK_GRK_GRK5_ST	P07550	ADRB2	P34947	GRK5	S261	S261F	261	Missense	central	0	yes	2.394	0.000	EPSD	COSMIC	1.854	Loss
AGC_GRK_GRK_GRK5_ST	P07550	ADRB2	P34947	GRK5	S355	S355F	355	Missense	central	0	yes	4.350	0.000	EPSD;PhosphoSitePlus	COSMIC	1.854	Loss
AGC_GRK_GRK_GRK5_ST	P07550	ADRB2	P34947	GRK5	S356	S355F	355	Missense	proximal	-1	no	4.158	4.202	EPSD;PhosphoSitePlus	COSMIC	1.854	Up-regulation
AGC_GRK_GRK_GRK5_ST	P07550	ADRB2	P34947	GRK5	T384	D380H	380	Missense	distal	-4	no	3.672	3.695	EPSD;PhosphoSitePlus	COSMIC;GDSC;CCLE	1.854	Up-regulation
AGC_GRK_GRK_GRK5_ST	P07550	ADRB2	P34947	GRK5	T384	E385V	385	Missense	proximal	1	no	3.672	3.587	EPSD;PhosphoSitePlus	COSMIC	1.854	Down-regulation
AGC_GRK_GRK_GRK5_ST	P26038	MSN	P34947	GRK5	S504	A498V	498	Missense	distal	-6	no	2.004	2.109	EPSD	COSMIC	1.854	Up-regulation
AGC_GRK_GRK_GRK5_ST	P26038	MSN	P34947	GRK5	T509	K514M	514	Missense	distal	5	no	1.943	2.111	EPSD	COSMIC	1.854	Up-regulation
AGC_GRK_GRK_GRK5_ST	P26038	MSN	P34947	GRK5	T509	R508H	508	Missense	proximal	-1	no	1.943	1.886	EPSD	COSMIC	1.854	Down-regulation
AGC_GRK_GRK_GRK5_ST	P26038	MSN	P34947	GRK5	T509	N515K	515	Missense	distal	6	no	1.943	1.965	EPSD	COSMIC	1.854	Up-regulation
AGC_GRK_GRK_GRK5_ST	P26038	MSN	P34947	GRK5	T510	K514M	514	Missense	distal	4	no	2.188	2.185	EPSD	COSMIC	1.854	Down-regulation
AGC_GRK_GRK_GRK5_ST	P26038	MSN	P34947	GRK5	T510	N515K	515	Missense	distal	5	no	2.188	1.717	EPSD	COSMIC	1.854	Loss
AGC_GRK_GRK_GRK5_ST	P34947	GRK5	P34947	GRK5	S484	T485S	485	Missense	proximal	1	no	4.708	4.413	EPSD;PhosphoSitePlus	COSMIC	1.854	Down-regulation
AGC_GRK_GRK_GRK5_ST	P04637	TP53	P34947	GRK5	S9	E11Q	11	Missense	proximal	2	no	2.827	2.623	EPSD	COSMIC;GDSC;CCLE	1.854	Down-regulation
AGC_GRK_GRK_GRK5_ST	P04637	TP53	P34947	GRK5	S9	Q16L	16	Missense	distal	7	no	2.827	2.760	EPSD	COSMIC;GDSC;CCLE	1.854	Down-regulation
AGC_GRK_GRK_GRK5_ST	P04637	TP53	P34947	GRK5	S9	P13S	13	Missense	distal	4	no	2.827	2.828	EPSD	COSMIC	1.854	Up-regulation
AGC_GRK_GRK_GRK5_ST	P04637	TP53	P34947	GRK5	S9	V10I	10	Missense	proximal	1	no	2.827	2.327	EPSD	COSMIC	1.854	Down-regulation
AGC_GRK_GRK_GRK5_ST	P04637	TP53	P34947	GRK5	S9	P8L	8	Missense	proximal	-1	no	2.827	2.837	EPSD	COSMIC	1.854	Up-regulation
AGC_GRK_GRK_GRK5_ST	P04637	TP53	P34947	GRK5	S9	P8S	8	Missense	proximal	-1	no	2.827	2.794	EPSD	COSMIC	1.854	Down-regulation
AGC_GRK_GRK_GRK5_ST	P04637	TP53	P34947	GRK5	S9	Q5H	5	Missense	distal	-4	no	2.827	2.838	EPSD	COSMIC	1.854	Up-regulation
AGC_GRK_GRK_GRK5_ST	P04637	TP53	P34947	GRK5	S9	V10G	10	Missense	proximal	1	no	2.827	2.432	EPSD	COSMIC	1.854	Down-regulation
AGC_GRK_GRK_GRK5_ST	P04637	TP53	P34947	GRK5	S9	E3G	3	Missense	distal	-6	no	2.827	3.040	EPSD	COSMIC	1.854	Up-regulation
AGC_GRK_GRK_GRK5_ST	P04637	TP53	P34947	GRK5	S9	D7H	7	Missense	proximal	-2	no	2.827	2.836	EPSD	COSMIC	1.854	Up-regulation
AGC_GRK_GRK_GRK5_ST	P04637	TP53	P34947	GRK5	S9	S9G	9	Missense	central	0	yes	2.827	0.000	EPSD	COSMIC	1.854	Loss
AGC_GRK_GRK_GRK5_ST	P04637	TP53	P34947	GRK5	S9	S15I	15	Missense	distal	6	no	2.827	2.825	EPSD	COSMIC	1.854	Down-regulation
AGC_GRK_GRK_GRK5_ST	P04637	TP53	P34947	GRK5	S9	D7Y	7	Missense	proximal	-2	no	2.827	2.840	EPSD	COSMIC	1.854	Up-regulation
AGC_GRK_GRK_GRK5_ST	P04637	TP53	P34947	GRK5	S33	M40I	40	Missense	distal	7	no	3.196	3.034	EPSD	COSMIC	1.854	Down-regulation
AGC_GRK_GRK_GRK5_ST	P04637	TP53	P34947	GRK5	S33	V31I	31	Missense	proximal	-2	no	3.196	3.198	EPSD	COSMIC;GDSC;CCLE	1.854	Up-regulation
AGC_GRK_GRK_GRK5_ST	P04637	TP53	P34947	GRK5	S33	P36L	36	Missense	distal	3	no	3.196	3.217	EPSD	COSMIC;GDSC;CCLE	1.854	Up-regulation
AGC_GRK_GRK_GRK5_ST	P04637	TP53	P34947	GRK5	S33	L35F	35	Missense	proximal	2	no	3.196	3.001	EPSD	COSMIC	1.854	Down-regulation
AGC_GRK_GRK_GRK5_ST	P04637	TP53	P34947	GRK5	S33	Q38L	38	Missense	distal	5	no	3.196	3.232	EPSD	COSMIC	1.854	Up-regulation
AGC_GRK_GRK_GRK5_ST	P04637	TP53	P34947	GRK5	S33	S37T	37	Missense	distal	4	no	3.196	3.195	EPSD	COSMIC	1.854	Down-regulation
AGC_GRK_GRK_GRK5_ST	P04637	TP53	P34947	GRK5	S33	L26P	26	Missense	distal	-7	no	3.196	3.118	EPSD	COSMIC	1.854	Down-regulation
AGC_GRK_GRK_GRK5_ST	P04637	TP53	P34947	GRK5	S33	P36S	36	Missense	distal	3	no	3.196	3.082	EPSD	COSMIC;GDSC;CCLE	1.854	Down-regulation
AGC_GRK_GRK_GRK5_ST	P04637	TP53	P34947	GRK5	S33	A39V	39	Missense	distal	6	no	3.196	3.234	EPSD	COSMIC	1.854	Up-regulation
AGC_GRK_GRK_GRK5_ST	P04637	TP53	P34947	GRK5	S33	A39S	39	Missense	distal	6	no	3.196	3.230	EPSD	COSMIC	1.854	Up-regulation
AGC_GRK_GRK_GRK5_ST	P04637	TP53	P34947	GRK5	S33	N30K	30	Missense	distal	-3	no	3.196	3.062	EPSD	COSMIC	1.854	Down-regulation
AGC_GRK_GRK_GRK5_ST	P04637	TP53	P34947	GRK5	S33	A39T	39	Missense	distal	6	no	3.196	3.242	EPSD	COSMIC	1.854	Up-regulation
AGC_GRK_GRK_GRK5_ST	P04637	TP53	P34947	GRK5	S33	P27T	27	Missense	distal	-6	no	3.196	3.165	EPSD	COSMIC	1.854	Down-regulation
AGC_GRK_GRK_GRK5_ST	P04637	TP53	P34947	GRK5	S33	P36R	36	Missense	distal	3	no	3.196	3.146	EPSD	COSMIC	1.854	Down-regulation
AGC_GRK_GRK_GRK5_ST	P04637	TP53	P34947	GRK5	S33	L35R	35	Missense	proximal	2	no	3.196	3.280	EPSD	COSMIC	1.854	Up-regulation
AGC_GRK_GRK_GRK5_ST	P04637	TP53	P34947	GRK5	S33	L35H	35	Missense	proximal	2	no	3.196	3.167	EPSD	COSMIC	1.854	Down-regulation
AGC_GRK_GRK_GRK5_ST	P04637	TP53	P34947	GRK5	S33	L35P	35	Missense	proximal	2	no	3.196	3.112	EPSD	COSMIC	1.854	Down-regulation
AGC_GRK_GRK_GRK5_ST	P04637	TP53	P34947	GRK5	S33	L35I	35	Missense	proximal	2	no	3.196	3.052	EPSD	COSMIC	1.854	Down-regulation
AGC_GRK_GRK_GRK5_ST	P04637	TP53	P34947	GRK5	S33	L35V	35	Missense	proximal	2	no	3.196	3.274	EPSD	COSMIC	1.854	Up-regulation
AGC_GRK_GRK_GRK5_ST	P04637	TP53	P34947	GRK5	S37	M40I	40	Missense	distal	3	no	2.381	2.391	EPSD	COSMIC	1.854	Up-regulation
AGC_GRK_GRK_GRK5_ST	P04637	TP53	P34947	GRK5	S37	V31I	31	Missense	distal	-6	no	2.381	2.456	EPSD	COSMIC;GDSC;CCLE	1.854	Up-regulation
AGC_GRK_GRK_GRK5_ST	P04637	TP53	P34947	GRK5	S37	P36L	36	Missense	proximal	-1	no	2.381	2.391	EPSD	COSMIC;GDSC;CCLE	1.854	Up-regulation
AGC_GRK_GRK_GRK5_ST	P04637	TP53	P34947	GRK5	S37	S33T	33	Missense	distal	-4	no	2.381	2.399	EPSD	COSMIC	1.854	Up-regulation
AGC_GRK_GRK_GRK5_ST	P04637	TP53	P34947	GRK5	S37	D41N	41	Missense	distal	4	no	2.381	2.373	EPSD	COSMIC	1.854	Down-regulation
AGC_GRK_GRK_GRK5_ST	P04637	TP53	P34947	GRK5	S37	L35F	35	Missense	proximal	-2	no	2.381	2.377	EPSD	COSMIC	1.854	Down-regulation
AGC_GRK_GRK_GRK5_ST	P04637	TP53	P34947	GRK5	S37	Q38L	38	Missense	proximal	1	no	2.381	2.580	EPSD	COSMIC	1.854	Up-regulation
AGC_GRK_GRK_GRK5_ST	P04637	TP53	P34947	GRK5	S37	M44I	44	Missense	distal	7	no	2.381	2.219	EPSD	COSMIC	1.854	Down-regulation
AGC_GRK_GRK_GRK5_ST	P04637	TP53	P34947	GRK5	S37	P36S	36	Missense	proximal	-1	no	2.381	2.348	EPSD	COSMIC;GDSC;CCLE	1.854	Down-regulation
AGC_GRK_GRK_GRK5_ST	P04637	TP53	P34947	GRK5	S37	A39V	39	Missense	proximal	2	no	2.381	2.332	EPSD	COSMIC	1.854	Down-regulation
AGC_GRK_GRK_GRK5_ST	P04637	TP53	P34947	GRK5	S37	A39S	39	Missense	proximal	2	no	2.381	2.259	EPSD	COSMIC	1.854	Down-regulation
AGC_GRK_GRK_GRK5_ST	P04637	TP53	P34947	GRK5	S37	D42Y	42	Missense	distal	5	no	2.381	2.464	EPSD	COSMIC	1.854	Up-regulation
AGC_GRK_GRK_GRK5_ST	P04637	TP53	P34947	GRK5	S37	M44R	44	Missense	distal	7	no	2.381	2.284	EPSD	COSMIC	1.854	Down-regulation
AGC_GRK_GRK_GRK5_ST	P04637	TP53	P34947	GRK5	S37	M44V	44	Missense	distal	7	no	2.381	2.272	EPSD	COSMIC	1.854	Down-regulation
AGC_GRK_GRK_GRK5_ST	P04637	TP53	P34947	GRK5	S37	N30K	30	Missense	distal	-7	no	2.381	2.249	EPSD	COSMIC	1.854	Down-regulation
AGC_GRK_GRK_GRK5_ST	P04637	TP53	P34947	GRK5	S37	M44T	44	Missense	distal	7	no	2.381	2.295	EPSD	COSMIC	1.854	Down-regulation
AGC_GRK_GRK_GRK5_ST	P04637	TP53	P34947	GRK5	S37	A39T	39	Missense	proximal	2	no	2.381	2.232	EPSD	COSMIC	1.854	Down-regulation
AGC_GRK_GRK_GRK5_ST	P04637	TP53	P34947	GRK5	S37	L43F	43	Missense	distal	6	no	2.381	2.410	EPSD	COSMIC	1.854	Up-regulation
AGC_GRK_GRK_GRK5_ST	P04637	TP53	P34947	GRK5	S37	D41H	41	Missense	distal	4	no	2.381	2.378	EPSD	COSMIC	1.854	Down-regulation
AGC_GRK_GRK_GRK5_ST	P04637	TP53	P34947	GRK5	S37	P36R	36	Missense	proximal	-1	no	2.381	2.406	EPSD	COSMIC	1.854	Up-regulation
AGC_GRK_GRK_GRK5_ST	P04637	TP53	P34947	GRK5	S37	L35R	35	Missense	proximal	-2	no	2.381	2.382	EPSD	COSMIC	1.854	Up-regulation
AGC_GRK_GRK_GRK5_ST	P04637	TP53	P34947	GRK5	S37	L35P	35	Missense	proximal	-2	no	2.381	2.380	EPSD	COSMIC	1.854	Down-regulation
AGC_GRK_GRK_GRK5_ST	P04637	TP53	P34947	GRK5	S37	L35I	35	Missense	proximal	-2	no	2.381	2.380	EPSD	COSMIC	1.854	Down-regulation
AGC_GRK_GRK_GRK5_ST	P04637	TP53	P34947	GRK5	S37	L35V	35	Missense	proximal	-2	no	2.381	2.378	EPSD	COSMIC	1.854	Down-regulation
AGC_GRK_GRK_GRK5_ST	P04637	TP53	P34947	GRK5	S37	D41E	41	Missense	distal	4	no	2.381	2.377	EPSD	COSMIC	1.854	Down-regulation
AGC_GRK_GRK_GRK5_ST	P04637	TP53	P34947	GRK5	T55	E56K	56	Missense	proximal	1	no	4.317	3.946	PhosphoSitePlus	COSMIC	1.854	Down-regulation
AGC_GRK_GRK_GRK5_ST	P04637	TP53	P34947	GRK5	T55	W53C	53	Missense	proximal	-2	no	4.317	4.300	PhosphoSitePlus	COSMIC	1.854	Down-regulation
AGC_GRK_GRK_GRK5_ST	P04637	TP53	P34947	GRK5	T55	P60A	60	Missense	distal	5	no	4.317	4.422	PhosphoSitePlus	COSMIC	1.854	Up-regulation
AGC_GRK_GRK_GRK5_ST	P04637	TP53	P34947	GRK5	T55	D61N	61	Missense	distal	6	no	4.317	4.274	PhosphoSitePlus	COSMIC	1.854	Down-regulation
AGC_GRK_GRK_GRK5_ST	P04637	TP53	P34947	GRK5	T55	D49Y	49	Missense	distal	-6	no	4.317	4.279	PhosphoSitePlus	COSMIC	1.854	Down-regulation
AGC_GRK_GRK_GRK5_ST	P04637	TP53	P34947	GRK5	T55	P58Q	58	Missense	distal	3	no	4.317	4.261	PhosphoSitePlus	COSMIC	1.854	Down-regulation
AGC_GRK_GRK_GRK5_ST	P04637	TP53	P34947	GRK5	T55	D49H	49	Missense	distal	-6	no	4.317	4.341	PhosphoSitePlus	COSMIC;GDSC;CCLE	1.854	Up-regulation
AGC_GRK_GRK_GRK5_ST	P04637	TP53	P34947	GRK5	T55	G59N	59	Missense	distal	4	no	4.317	4.309	PhosphoSitePlus	COSMIC	1.854	Down-regulation
AGC_GRK_GRK_GRK5_ST	P04637	TP53	P34947	GRK5	T55	G59C	59	Missense	distal	4	no	4.317	4.323	PhosphoSitePlus	COSMIC	1.854	Up-regulation
AGC_GRK_GRK_GRK5_ST	P04637	TP53	P34947	GRK5	T55	P60R	60	Missense	distal	5	no	4.317	4.393	PhosphoSitePlus	COSMIC	1.854	Up-regulation
AGC_GRK_GRK_GRK5_ST	P04637	TP53	P34947	GRK5	T55	G59D	59	Missense	distal	4	no	4.317	4.318	PhosphoSitePlus	COSMIC	1.854	Up-regulation
AGC_GRK_GRK_GRK5_ST	P04637	TP53	P34947	GRK5	T55	D48H	48	Missense	distal	-7	no	4.317	4.251	PhosphoSitePlus	COSMIC	1.854	Down-regulation
AGC_GRK_GRK_GRK5_ST	P04637	TP53	P34947	GRK5	T55	P58L	58	Missense	distal	3	no	4.317	4.338	PhosphoSitePlus	COSMIC	1.854	Up-regulation
AGC_GRK_GRK_GRK5_ST	P04637	TP53	P34947	GRK5	T55	D49N	49	Missense	distal	-6	no	4.317	4.202	PhosphoSitePlus	COSMIC	1.854	Down-regulation
AGC_GRK_GRK_GRK5_ST	P04637	TP53	P34947	GRK5	T55	D61H	61	Missense	distal	6	no	4.317	4.322	PhosphoSitePlus	COSMIC	1.854	Up-regulation
AGC_GRK_GRK_GRK5_ST	P04637	TP53	P34947	GRK5	T55	Q52H	52	Missense	distal	-3	no	4.317	4.286	PhosphoSitePlus	COSMIC	1.854	Down-regulation
AGC_GRK_GRK_GRK5_ST	P04637	TP53	P34947	GRK5	T55	F54L	54	Missense	proximal	-1	no	4.317	4.316	PhosphoSitePlus	COSMIC	1.854	Down-regulation
AGC_GRK_GRK_GRK5_ST	P04637	TP53	P34947	GRK5	T55	D49V	49	Missense	distal	-6	no	4.317	4.265	PhosphoSitePlus	COSMIC	1.854	Down-regulation
AGC_GRK_GRK_GRK5_ST	P04637	TP53	P34947	GRK5	T55	P60L	60	Missense	distal	5	no	4.317	4.299	PhosphoSitePlus	COSMIC	1.854	Down-regulation
AGC_GRK_GRK_GRK5_ST	P04637	TP53	P34947	GRK5	T55	P60S	60	Missense	distal	5	no	4.317	4.245	PhosphoSitePlus	COSMIC	1.854	Down-regulation
AGC_GRK_GRK_GRK5_ST	P04637	TP53	P34947	GRK5	T55	G59R	59	Missense	distal	4	no	4.317	4.315	PhosphoSitePlus	COSMIC	1.854	Down-regulation
AGC_GRK_GRK_GRK5_ST	P04637	TP53	P34947	GRK5	T55	E56V	56	Missense	proximal	1	no	4.317	4.232	PhosphoSitePlus	COSMIC	1.854	Down-regulation
AGC_GRK_GRK_GRK5_ST	P04637	TP53	P34947	GRK5	T55	P60T	60	Missense	distal	5	no	4.317	4.329	PhosphoSitePlus	COSMIC	1.854	Up-regulation
AGC_GRK_GRK_GRK5_ST	P04637	TP53	P34947	GRK5	T55	E62D	62	Missense	distal	7	no	4.317	4.158	PhosphoSitePlus	COSMIC	1.854	Down-regulation
AGC_GRK_GRK_GRK5_ST	P04637	TP53	P34947	GRK5	T55	P58R	58	Missense	distal	3	no	4.317	4.267	PhosphoSitePlus	COSMIC	1.854	Down-regulation
AGC_GRK_GRK_GRK5_ST	P04637	TP53	P34947	GRK5	T55	P60Q	60	Missense	distal	5	no	4.317	4.263	PhosphoSitePlus	COSMIC	1.854	Down-regulation
AGC_GRK_GRK_GRK5_ST	P04637	TP53	P34947	GRK5	T55	P58N	58	Missense	distal	3	no	4.317	4.107	PhosphoSitePlus	COSMIC	1.854	Down-regulation
AGC_GRK_GRK_GRK5_ST	P04637	TP53	P34947	GRK5	T55	P58S	58	Missense	distal	3	no	4.317	4.203	PhosphoSitePlus	COSMIC	1.854	Down-regulation
AGC_GRK_GRK_GRK5_ST	P04637	TP53	P34947	GRK5	T55	P58T	58	Missense	distal	3	no	4.317	4.329	PhosphoSitePlus	COSMIC	1.854	Up-regulation
AGC_GRK_GRK_GRK5_ST	P04637	TP53	P34947	GRK5	T55	D49E	49	Missense	distal	-6	no	4.317	4.185	PhosphoSitePlus	COSMIC	1.854	Down-regulation
AGC_GRK_GRK_GRK5_ST	P04637	TP53	P34947	GRK5	T55	P58F	58	Missense	distal	3	no	4.317	4.465	PhosphoSitePlus	COSMIC	1.854	Up-regulation
AGC_GRK_GRK_GRK5_ST	P04637	TP53	P34947	GRK5	T55	D49G	49	Missense	distal	-6	no	4.317	4.397	PhosphoSitePlus	COSMIC	1.854	Up-regulation
AGC_GRK_GRK_GRK5_ST	P04637	TP53	P34947	GRK5	T55	P60H	60	Missense	distal	5	no	4.317	4.285	PhosphoSitePlus	COSMIC	1.854	Down-regulation
AGC_GRK_GRK_GRK5_ST	P04637	TP53	P34947	GRK5	T55	P58H	58	Missense	distal	3	no	4.317	4.226	PhosphoSitePlus	COSMIC	1.854	Down-regulation
AGC_GRK_GRK_GRK5_ST	P04637	TP53	P34947	GRK5	T55	P58A	58	Missense	distal	3	no	4.317	4.154	PhosphoSitePlus	COSMIC	1.854	Down-regulation
AGC_GRK_GRK_GRK5_ST	P04637	TP53	P34947	GRK5	T55	D48A	48	Missense	distal	-7	no	4.317	4.375	PhosphoSitePlus	COSMIC	1.854	Up-regulation
AGC_GRK_GRK_GRK5_ST	P04637	TP53	P34947	GRK5	T55	E62G	62	Missense	distal	7	no	4.317	4.055	PhosphoSitePlus	COSMIC	1.854	Down-regulation
AGC_GRK_GRK_GRK5_ST	P04637	TP53	P34947	GRK5	T55	D48Y	48	Missense	distal	-7	no	4.317	4.289	PhosphoSitePlus	COSMIC	1.854	Down-regulation
AGC_GRK_GRK_GRK5_ST	P04637	TP53	P34947	GRK5	T55	E62V	62	Missense	distal	7	no	4.317	4.134	PhosphoSitePlus	COSMIC	1.854	Down-regulation
AGC_GRK_GRK_GRK5_ST	P04637	TP53	P34947	GRK5	T55	D48E	48	Missense	distal	-7	no	4.317	4.377	PhosphoSitePlus	COSMIC	1.854	Up-regulation
AGC_GRK_GRK_GRK5_ST	P04637	TP53	P34947	GRK5	T55	D49I	49	Missense	distal	-6	no	4.317	4.340	PhosphoSitePlus	COSMIC	1.854	Up-regulation
AGC_GRK_GRK_GRK5_ST	P04637	TP53	P34947	GRK5	T55	P60C	60	Missense	distal	5	no	4.317	4.014	PhosphoSitePlus	COSMIC	1.854	Down-regulation
AGC_GRK_GRK_GRK5_ST	P04637	TP53	P34947	GRK5	T150	P151N	151	Missense	proximal	1	no	1.750	2.095	EPSD	COSMIC	1.854	Gain
AGC_GRK_GRK_GRK5_ST	P04637	TP53	P34947	GRK5	T150	P152A	152	Missense	proximal	2	no	1.750	1.961	EPSD	COSMIC	1.854	Gain
AGC_GRK_GRK_GRK5_ST	P04637	TP53	P34947	GRK5	T150	V147E	147	Missense	distal	-3	no	1.750	1.905	EPSD	COSMIC	1.854	Gain
AGC_GRK_GRK_GRK5_ST	P04637	TP53	P34947	GRK5	T150	V147A	147	Missense	distal	-3	no	1.750	1.874	EPSD	COSMIC	1.854	Gain
AGC_GRK_GRK_GRK5_ST	P04637	TP53	P34947	GRK5	T150	V157E	157	Missense	distal	7	no	1.750	1.934	EPSD	COSMIC	1.854	Gain
AGC_GRK_GRK_GRK5_ST	P04637	TP53	P34947	GRK5	T150	P153F	153	Missense	distal	3	no	1.750	1.899	EPSD	COSMIC	1.854	Gain
AGC_GRK_GRK_GRK5_ST	P04637	TP53	P34947	GRK5	S313	N310T	310	Missense	distal	-3	no	1.908	1.841	EPSD	COSMIC	1.854	Loss
AGC_GRK_GRK_GRK5_ST	P04637	TP53	P34947	GRK5	S313	Q317R	317	Missense	distal	4	no	1.908	1.906	EPSD	COSMIC	1.854	Down-regulation
AGC_GRK_GRK_GRK5_ST	P04637	TP53	P34947	GRK5	S313	P309S	309	Missense	distal	-4	no	1.908	1.892	EPSD	COSMIC;GDSC;CCLE	1.854	Down-regulation
AGC_GRK_GRK_GRK5_ST	P04637	TP53	P34947	GRK5	S313	K319E	319	Missense	distal	6	no	1.908	1.910	EPSD	COSMIC	1.854	Up-regulation
AGC_GRK_GRK_GRK5_ST	P04637	TP53	P34947	GRK5	S313	K320N	320	Missense	distal	7	no	1.908	1.941	EPSD	COSMIC;GDSC;CCLE	1.854	Up-regulation
AGC_GRK_GRK_GRK5_ST	P04637	TP53	P34947	GRK5	S313	N310L	310	Missense	distal	-3	no	1.908	1.668	EPSD	COSMIC	1.854	Loss
AGC_GRK_GRK_GRK5_ST	P04637	TP53	P34947	GRK5	S313	T312S	312	Missense	proximal	-1	no	1.908	1.891	EPSD	COSMIC	1.854	Down-regulation
AGC_GRK_GRK_GRK5_ST	P04637	TP53	P34947	GRK5	S313	N311Y	311	Missense	proximal	-2	no	1.908	1.902	EPSD	COSMIC	1.854	Down-regulation
AGC_GRK_GRK_GRK5_ST	P04637	TP53	P34947	GRK5	S313	R306P	306	Missense	distal	-7	no	1.908	1.876	EPSD	COSMIC	1.854	Down-regulation
AGC_GRK_GRK_GRK5_ST	P04637	TP53	P34947	GRK5	S313	A307T	307	Missense	distal	-6	no	1.908	2.018	EPSD	COSMIC	1.854	Up-regulation
AGC_GRK_GRK_GRK5_ST	P04637	TP53	P34947	GRK5	S313	N311K	311	Missense	proximal	-2	no	1.908	1.891	EPSD	COSMIC	1.854	Down-regulation
AGC_GRK_GRK_GRK5_ST	P04637	TP53	P34947	GRK5	S313	S315P	315	Missense	proximal	2	no	1.908	1.819	EPSD	COSMIC	1.854	Loss
AGC_GRK_GRK_GRK5_ST	P04637	TP53	P34947	GRK5	S313	N310H	310	Missense	distal	-3	no	1.908	1.728	EPSD	COSMIC	1.854	Loss
AGC_GRK_GRK_GRK5_ST	P04637	TP53	P34947	GRK5	S313	R306Q	306	Missense	distal	-7	no	1.908	1.900	EPSD	COSMIC	1.854	Down-regulation
AGC_GRK_GRK_GRK5_ST	P04637	TP53	P34947	GRK5	S313	S314C	314	Missense	proximal	1	no	1.908	1.593	EPSD	COSMIC	1.854	Loss
AGC_GRK_GRK_GRK5_ST	P04637	TP53	P34947	GRK5	S313	P318A	318	Missense	distal	5	no	1.908	2.012	EPSD	COSMIC	1.854	Up-regulation
AGC_GRK_GRK_GRK5_ST	P04637	TP53	P34947	GRK5	S313	P316L	316	Missense	distal	3	no	1.908	1.929	EPSD	COSMIC	1.854	Up-regulation
AGC_GRK_GRK_GRK5_ST	P04637	TP53	P34947	GRK5	S313	L308M	308	Missense	distal	-5	no	1.908	1.866	EPSD	COSMIC	1.854	Down-regulation
AGC_GRK_GRK_GRK5_ST	P04637	TP53	P34947	GRK5	S313	S313C	313	Missense	central	0	yes	1.908	0.000	EPSD	COSMIC	1.854	Loss
AGC_GRK_GRK_GRK5_ST	P04637	TP53	P34947	GRK5	S313	N311H	311	Missense	proximal	-2	no	1.908	1.899	EPSD	COSMIC	1.854	Down-regulation
AGC_GRK_GRK_GRK5_ST	P04637	TP53	P34947	GRK5	S313	L308V	308	Missense	distal	-5	no	1.908	1.969	EPSD	COSMIC	1.854	Up-regulation
AGC_GRK_GRK_GRK5_ST	P04637	TP53	P34947	GRK5	S313	S314F	314	Missense	proximal	1	no	1.908	1.899	EPSD	COSMIC	1.854	Down-regulation
AGC_GRK_GRK_GRK5_ST	P04637	TP53	P34947	GRK5	S313	K319R	319	Missense	distal	6	no	1.908	1.916	EPSD	COSMIC	1.854	Up-regulation
AGC_GRK_GRK_GRK5_ST	P04637	TP53	P34947	GRK5	S313	T312A	312	Missense	proximal	-1	no	1.908	1.796	EPSD	COSMIC	1.854	Loss
AGC_GRK_GRK_GRK5_ST	P04637	TP53	P34947	GRK5	S313	N310D	310	Missense	distal	-3	no	1.908	1.815	EPSD	COSMIC	1.854	Loss
AGC_GRK_GRK_GRK5_ST	P04637	TP53	P34947	GRK5	S313	N311D	311	Missense	proximal	-2	no	1.908	1.890	EPSD	COSMIC	1.854	Down-regulation
AGC_GRK_GRK_GRK5_ST	P04637	TP53	P34947	GRK5	S313	S313N	313	Missense	central	0	yes	1.908	0.000	EPSD	COSMIC	1.854	Loss
AGC_GRK_GRK_GRK5_ST	P04637	TP53	P34947	GRK5	S313	Q317P	317	Missense	distal	4	no	1.908	1.907	EPSD	COSMIC	1.854	Down-regulation
AGC_GRK_GRK_GRK5_ST	P04637	TP53	P34947	GRK5	S313	A307S	307	Missense	distal	-6	no	1.908	2.025	EPSD	COSMIC	1.854	Up-regulation
AGC_GRK_GRK_GRK5_ST	P04637	TP53	P34947	GRK5	S313	P316S	316	Missense	distal	3	no	1.908	1.793	EPSD	COSMIC	1.854	Loss
AGC_GRK_GRK_GRK5_ST	O60353	FZD6	P34947	GRK5	S517	R513K	513	Missense	distal	-4	no	2.447	2.487	EPSD	COSMIC	1.854	Up-regulation
AGC_GRK_GRK_GRK5_ST	P37840	SNCA	P34947	GRK5	S129	A124S	124	Missense	distal	-5	no	1.896	2.121	PhosphoSitePlus	COSMIC	1.854	Up-regulation
AGC_GRK_GRK_GRK5_ST	P37840	SNCA	P34947	GRK5	S129	E130V	130	Missense	proximal	1	no	1.896	1.810	PhosphoSitePlus	COSMIC	1.854	Loss
AGC_GRK_GRK_GRK5_ST	P37840	SNCA	P34947	GRK5	S129	D135E	135	Missense	distal	6	no	1.896	1.877	PhosphoSitePlus	COSMIC;GDSC;CCLE	1.854	Down-regulation
AGC_GRK_GRK_GRK5_ST	P37840	SNCA	P34947	GRK5	S129	E130A	130	Missense	proximal	1	no	1.896	1.699	PhosphoSitePlus	COSMIC	1.854	Loss
AGC_GRK_GRK_GRK5_ST	P37840	SNCA	P34947	GRK5	S129	E123K	123	Missense	distal	-6	no	1.896	1.934	PhosphoSitePlus	COSMIC	1.854	Up-regulation
CMGC_CK2_CSNK2A2_ST	P18887	XRCC1	P19784	CSNK2A2	S408	E411K	411	Missense	distal	3	no	0.001	0.000	EPSD	COSMIC	0.001	Loss
CMGC_CK2_CSNK2A2_ST	P18887	XRCC1	P19784	CSNK2A2	T488	T488M	488	Missense	central	0	yes	0.001	0.000	PhosphoSitePlus;EPSD	COSMIC	0.001	Loss
CMGC_CK2_CSNK2A2_ST	P35222	CTNNB1	P19784	CSNK2A2	T3	T3I	3	Missense	central	0	yes	0.001	0.000	EPSD	COSMIC	0.001	Loss
CMGC_CK2_CSNK2A2_ST	P35222	CTNNB1	P19784	CSNK2A2	T3	D6G	6	Missense	distal	3	no	0.001	0.000	EPSD	COSMIC;GDSC;CCLE	0.001	Loss
CMGC_CK2_CSNK2A2_ST	P35222	CTNNB1	P19784	CSNK2A2	S29	S29P	29	Missense	central	0	yes	0.001	0.000	EPSD;PhosphoSitePlus	COSMIC	0.001	Loss
CMGC_CK2_CSNK2A2_ST	P35222	CTNNB1	P19784	CSNK2A2	S29	S29F	29	Missense	central	0	yes	0.001	0.000	EPSD;PhosphoSitePlus	COSMIC	0.001	Loss
CMGC_CK2_CSNK2A2_ST	P35222	CTNNB1	P19784	CSNK2A2	S29	S29Y	29	Missense	central	0	yes	0.001	0.000	EPSD;PhosphoSitePlus	COSMIC	0.001	Loss
CMGC_CK2_CSNK2A2_ST	P35222	CTNNB1	P19784	CSNK2A2	S29	S29A	29	Missense	central	0	yes	0.001	0.000	EPSD;PhosphoSitePlus	COSMIC	0.001	Loss
CMGC_CK2_CSNK2A2_ST	P35222	CTNNB1	P19784	CSNK2A2	S29	D32C	32	Missense	distal	3	no	0.001	0.000	EPSD;PhosphoSitePlus	COSMIC	0.001	Loss
CMGC_CK2_CSNK2A2_ST	P35222	CTNNB1	P19784	CSNK2A2	S29	D32F	32	Missense	distal	3	no	0.001	0.000	EPSD;PhosphoSitePlus	COSMIC	0.001	Loss
CMGC_CK2_CSNK2A2_ST	P35222	CTNNB1	P19784	CSNK2A2	S29	D32X	32	Missense	distal	3	no	0.001	0.000	EPSD;PhosphoSitePlus	COSMIC	0.001	Loss
CMGC_CK2_CSNK2A2_ST	P35222	CTNNB1	P19784	CSNK2A2	T42	S45E	45	Missense	distal	3	no	0.000	0.001	EPSD	COSMIC	0.001	Gain
CMGC_CK2_CSNK2A2_ST	P35222	CTNNB1	P19784	CSNK2A2	S45	G48D	48	Missense	distal	3	no	0.000	0.001	EPSD	COSMIC	0.001	Gain
CMGC_CK2_CSNK2A2_ST	P35222	CTNNB1	P19784	CSNK2A2	S47	G50D	50	Missense	distal	3	no	0.000	0.001	EPSD	COSMIC	0.001	Gain
CMGC_CK2_CSNK2A2_ST	P35222	CTNNB1	P19784	CSNK2A2	S73	Q76E	76	Missense	distal	3	no	0.000	0.001	EPSD	COSMIC	0.001	Gain
CMGC_CK2_CSNK2A2_ST	P35222	CTNNB1	P19784	CSNK2A2	S184	A187D	187	Missense	distal	3	no	0.000	0.001	EPSD	COSMIC	0.001	Gain
CMGC_CK2_CSNK2A2_ST	P35222	CTNNB1	P19784	CSNK2A2	S246	S246L	246	Missense	central	0	yes	0.001	0.000	EPSD	COSMIC	0.001	Loss
CMGC_CK2_CSNK2A2_ST	P35222	CTNNB1	P19784	CSNK2A2	T551	G554D	554	Missense	distal	3	no	0.000	0.001	EPSD	COSMIC	0.001	Gain
CMGC_CK2_CSNK2A2_ST	P35222	CTNNB1	P19784	CSNK2A2	S646	S646F	646	Missense	central	0	yes	0.001	0.000	EPSD	COSMIC	0.001	Loss
CMGC_CK2_CSNK2A2_ST	Q96SB4	SRPK1	P19784	CSNK2A2	S134	N137D	137	Missense	distal	3	no	0.000	0.001	EPSD	COSMIC	0.001	Gain
CMGC_CK2_CSNK2A2_ST	Q9UQE7	SMC3	P19784	CSNK2A2	T18	D21V	21	Missense	distal	3	no	0.001	0.000	EPSD	COSMIC	0.001	Loss
CMGC_CK2_CSNK2A2_ST	Q9UQE7	SMC3	P19784	CSNK2A2	S387	E390Q	390	Missense	distal	3	no	0.001	0.000	EPSD	COSMIC	0.001	Loss
CMGC_CK2_CSNK2A2_ST	Q9UQE7	SMC3	P19784	CSNK2A2	S1077	G1080D	1080	Missense	distal	3	no	0.000	0.001	EPSD	COSMIC	0.001	Gain
CMGC_CK2_CSNK2A2_ST	P67870	CSNK2B	P19784	CSNK2A2	S4	V7E	7	Missense	distal	3	no	0.000	0.002	EPSD	COSMIC	0.001	Gain
CMGC_CK2_CSNK2A2_ST	Q16543	CDC37	P19784	CSNK2A2	S5	D8G	8	Missense	distal	3	no	0.001	0.000	EPSD	COSMIC	0.001	Loss
CMGC_CK2_CSNK2A2_ST	Q16543	CDC37	P19784	CSNK2A2	S127	N130D	130	Missense	distal	3	no	0.000	0.001	EPSD	COSMIC	0.001	Gain
CMGC_CK2_CSNK2A2_ST	Q16543	CDC37	P19784	CSNK2A2	T131	T131I	131	Missense	central	0	yes	0.001	0.000	EPSD	COSMIC	0.001	Loss
CMGC_CK2_CSNK2A2_ST	Q16543	CDC37	P19784	CSNK2A2	T131	E134K	134	Missense	distal	3	no	0.001	0.000	EPSD	COSMIC	0.001	Loss
CMGC_CK2_CSNK2A2_ST	Q16543	CDC37	P19784	CSNK2A2	T370	T370M	370	Missense	central	0	yes	0.001	0.000	EPSD	COSMIC;CCLE	0.001	Loss
CMGC_CK2_CSNK2A2_ST	O15350	TP73	P19784	CSNK2A2	T27	D30A	30	Missense	distal	3	no	0.001	0.000	PhosphoSitePlus	COSMIC	0.001	Loss
CMGC_CK2_CSNK2A2_ST	O15350	TP73	P19784	CSNK2A2	S47	D50Y	50	Missense	distal	3	no	0.001	0.000	EPSD	COSMIC;GDSC;CCLE	0.001	Loss
CMGC_CK2_CSNK2A2_ST	Q00613	HSF1	P19784	CSNK2A2	S283	S283N	283	Missense	central	0	yes	0.001	0.000	EPSD	COSMIC	0.001	Loss
CMGC_CK2_CSNK2A2_ST	Q00613	HSF1	P19784	CSNK2A2	T355	E358K	358	Missense	distal	3	no	0.001	0.000	EPSD	COSMIC	0.001	Loss
CMGC_CK2_CSNK2A2_ST	Q00613	HSF1	P19784	CSNK2A2	S444	E447K	447	Missense	distal	3	no	0.001	0.000	EPSD	COSMIC	0.001	Loss
CMGC_CK2_CSNK2A2_ST	Q00613	HSF1	P19784	CSNK2A2	T516	E519K	519	Missense	distal	3	no	0.001	0.000	EPSD	COSMIC	0.001	Loss
TKL_LRRK_LRRK2_ST	Q5S007	LRRK2	Q5S007	LRRK2	T358	Y354C	354	Missense	distal	-4	no	16.532	17.160	EPSD	COSMIC	15.080	Up-regulation
TKL_LRRK_LRRK2_ST	Q5S007	LRRK2	Q5S007	LRRK2	T424	L425F	425	Missense	proximal	1	no	17.358	17.184	EPSD;PhosphoSitePlus	COSMIC;CCLE	15.080	Down-regulation
TKL_LRRK_LRRK2_ST	Q5S007	LRRK2	Q5S007	LRRK2	S588	D587Y	587	Missense	proximal	-1	no	13.849	15.206	EPSD	COSMIC	15.080	Gain
TKL_LRRK_LRRK2_ST	Q5S007	LRRK2	Q5S007	LRRK2	T776	T776M	776	Missense	central	0	yes	16.256	0.000	EPSD;PhosphoSitePlus	COSMIC	15.080	Loss
TKL_LRRK_LRRK2_ST	Q5S007	LRRK2	Q5S007	LRRK2	T826	S827F	827	Missense	proximal	1	no	15.693	15.786	EPSD;PhosphoSitePlus	COSMIC	15.080	Up-regulation
TKL_LRRK_LRRK2_ST	Q5S007	LRRK2	Q5S007	LRRK2	T826	G819V	819	Missense	distal	-7	no	15.693	15.971	EPSD;PhosphoSitePlus	COSMIC	15.080	Up-regulation
TKL_LRRK_LRRK2_ST	Q5S007	LRRK2	Q5S007	LRRK2	T826	G819R	819	Missense	distal	-7	no	15.693	16.295	EPSD;PhosphoSitePlus	COSMIC	15.080	Up-regulation
TKL_LRRK_LRRK2_ST	Q5S007	LRRK2	Q5S007	LRRK2	T826	K831Q	831	Missense	distal	5	no	15.693	15.037	EPSD;PhosphoSitePlus	COSMIC	15.080	Loss
TKL_LRRK_LRRK2_ST	Q5S007	LRRK2	Q5S007	LRRK2	T833	S827F	827	Missense	distal	-6	no	16.763	16.289	EPSD;PhosphoSitePlus	COSMIC	15.080	Down-regulation
TKL_LRRK_LRRK2_ST	Q5S007	LRRK2	Q5S007	LRRK2	T833	K831Q	831	Missense	proximal	-2	no	16.763	16.637	EPSD;PhosphoSitePlus	COSMIC	15.080	Down-regulation
TKL_LRRK_LRRK2_ST	Q5S007	LRRK2	Q5S007	LRRK2	T833	S837Y	837	Missense	distal	4	no	16.763	14.821	EPSD;PhosphoSitePlus	COSMIC	15.080	Loss
TKL_LRRK_LRRK2_ST	Q5S007	LRRK2	Q5S007	LRRK2	T838	M842L	842	Missense	distal	4	no	17.022	17.431	EPSD;PhosphoSitePlus	COSMIC	15.080	Up-regulation
TKL_LRRK_LRRK2_ST	Q5S007	LRRK2	Q5S007	LRRK2	T838	M842I	842	Missense	distal	4	no	17.022	17.271	EPSD;PhosphoSitePlus	COSMIC	15.080	Up-regulation
TKL_LRRK_LRRK2_ST	Q5S007	LRRK2	Q5S007	LRRK2	T838	K831Q	831	Missense	distal	-7	no	17.022	15.995	EPSD;PhosphoSitePlus	COSMIC	15.080	Down-regulation
TKL_LRRK_LRRK2_ST	Q5S007	LRRK2	Q5S007	LRRK2	T838	S837Y	837	Missense	proximal	-1	no	17.022	17.531	EPSD;PhosphoSitePlus	COSMIC	15.080	Up-regulation
TKL_LRRK_LRRK2_ST	Q5S007	LRRK2	Q5S007	LRRK2	S1219	W1217L	1217	Missense	proximal	-2	no	15.640	16.079	EPSD	COSMIC	15.080	Up-regulation
TKL_LRRK_LRRK2_ST	Q5S007	LRRK2	Q5S007	LRRK2	S1219	N1221K	1221	Missense	proximal	2	no	15.640	16.458	EPSD	COSMIC	15.080	Up-regulation
TKL_LRRK_LRRK2_ST	Q5S007	LRRK2	Q5S007	LRRK2	S1219	G1213S	1213	Missense	distal	-6	no	15.640	17.112	EPSD	COSMIC;GDSC;CCLE	15.080	Up-regulation
TKL_LRRK_LRRK2_ST	Q5S007	LRRK2	Q5S007	LRRK2	S1253	L1252F	1252	Missense	proximal	-1	no	15.314	14.288	EPSD;PhosphoSitePlus	COSMIC	15.080	Loss
TKL_LRRK_LRRK2_ST	Q5S007	LRRK2	Q5S007	LRRK2	S1253	R1246K	1246	Missense	distal	-7	no	15.314	15.815	EPSD;PhosphoSitePlus	COSMIC	15.080	Up-regulation
TKL_LRRK_LRRK2_ST	Q5S007	LRRK2	Q5S007	LRRK2	S1283	M1288I	1288	Missense	distal	5	no	15.818	16.056	EPSD;PhosphoSitePlus	COSMIC	15.080	Up-regulation
TKL_LRRK_LRRK2_ST	Q5S007	LRRK2	Q5S007	LRRK2	S1283	N1286Y	1286	Missense	distal	3	no	15.818	15.824	EPSD;PhosphoSitePlus	COSMIC	15.080	Up-regulation
TKL_LRRK_LRRK2_ST	Q5S007	LRRK2	Q5S007	LRRK2	S1292	M1288I	1288	Missense	distal	-4	no	17.748	17.336	EPSD;PhosphoSitePlus	COSMIC	15.080	Down-regulation
TKL_LRRK_LRRK2_ST	Q5S007	LRRK2	Q5S007	LRRK2	S1292	I1294V	1294	Missense	proximal	2	no	17.748	17.483	EPSD;PhosphoSitePlus	COSMIC	15.080	Down-regulation
TKL_LRRK_LRRK2_ST	Q5S007	LRRK2	Q5S007	LRRK2	S1292	N1286Y	1286	Missense	distal	-6	no	17.748	19.123	EPSD;PhosphoSitePlus	COSMIC	15.080	Up-regulation
TKL_LRRK_LRRK2_ST	Q5S007	LRRK2	Q5S007	LRRK2	S1292	L1299F	1299	Missense	distal	7	no	17.748	17.782	EPSD;PhosphoSitePlus	COSMIC;CCLE	15.080	Up-regulation
TKL_LRRK_LRRK2_ST	Q5S007	LRRK2	Q5S007	LRRK2	S1403	G1397C	1397	Missense	distal	-6	no	16.773	17.981	EPSD;PhosphoSitePlus	COSMIC;GDSC	15.080	Up-regulation
TKL_LRRK_LRRK2_ST	Q5S007	LRRK2	Q5S007	LRRK2	S1403	R1398S	1398	Missense	distal	-5	no	16.773	16.660	EPSD;PhosphoSitePlus	COSMIC;CCLE	15.080	Down-regulation
TKL_LRRK_LRRK2_ST	Q5S007	LRRK2	Q5S007	LRRK2	T1404	G1397C	1397	Missense	distal	-7	no	16.083	15.769	EPSD;PhosphoSitePlus	COSMIC;GDSC	15.080	Down-regulation
TKL_LRRK_LRRK2_ST	Q5S007	LRRK2	Q5S007	LRRK2	T1404	R1398S	1398	Missense	distal	-6	no	16.083	16.654	EPSD;PhosphoSitePlus	COSMIC;CCLE	15.080	Up-regulation
TKL_LRRK_LRRK2_ST	Q5S007	LRRK2	Q5S007	LRRK2	T1410	R1412Q	1412	Missense	proximal	2	no	17.094	16.519	EPSD;PhosphoSitePlus	COSMIC	15.080	Down-regulation
TKL_LRRK_LRRK2_ST	Q5S007	LRRK2	Q5S007	LRRK2	T1410	A1417S	1417	Missense	distal	7	no	17.094	17.092	EPSD;PhosphoSitePlus	COSMIC	15.080	Down-regulation
TKL_LRRK_LRRK2_ST	Q5S007	LRRK2	Q5S007	LRRK2	S1443	V1450I	1450	Missense	distal	7	no	16.548	16.589	EPSD;PhosphoSitePlus	COSMIC;GDSC	15.080	Up-regulation
TKL_LRRK_LRRK2_ST	Q5S007	LRRK2	Q5S007	LRRK2	S1443	L1449F	1449	Missense	distal	6	no	16.548	15.547	EPSD;PhosphoSitePlus	COSMIC	15.080	Down-regulation
TKL_LRRK_LRRK2_ST	Q5S007	LRRK2	Q5S007	LRRK2	S1444	V1450I	1450	Missense	distal	6	no	15.938	16.180	EPSD;PhosphoSitePlus	COSMIC;GDSC	15.080	Up-regulation
TKL_LRRK_LRRK2_ST	Q5S007	LRRK2	Q5S007	LRRK2	S1444	L1449F	1449	Missense	distal	5	no	15.938	16.622	EPSD;PhosphoSitePlus	COSMIC	15.080	Up-regulation
TKL_LRRK_LRRK2_ST	Q5S007	LRRK2	Q5S007	LRRK2	S1444	S1443T	1443	Missense	proximal	-1	no	15.938	16.153	EPSD;PhosphoSitePlus	COSMIC	15.080	Up-regulation
TKL_LRRK_LRRK2_ST	Q5S007	LRRK2	Q5S007	LRRK2	S1445	V1450I	1450	Missense	distal	5	no	15.500	15.143	EPSD;PhosphoSitePlus	COSMIC;GDSC	15.080	Down-regulation
TKL_LRRK_LRRK2_ST	Q5S007	LRRK2	Q5S007	LRRK2	S1445	L1449F	1449	Missense	distal	4	no	15.500	14.367	EPSD;PhosphoSitePlus	COSMIC	15.080	Loss
TKL_LRRK_LRRK2_ST	Q5S007	LRRK2	Q5S007	LRRK2	S1445	S1443T	1443	Missense	proximal	-2	no	15.500	15.202	EPSD;PhosphoSitePlus	COSMIC	15.080	Down-regulation
TKL_LRRK_LRRK2_ST	Q5S007	LRRK2	Q5S007	LRRK2	T1452	V1450I	1450	Missense	proximal	-2	no	16.299	16.793	EPSD;PhosphoSitePlus	COSMIC;GDSC	15.080	Up-regulation
TKL_LRRK_LRRK2_ST	Q5S007	LRRK2	Q5S007	LRRK2	T1452	D1458G	1458	Missense	distal	6	no	16.299	16.746	EPSD;PhosphoSitePlus	COSMIC	15.080	Up-regulation
TKL_LRRK_LRRK2_ST	Q5S007	LRRK2	Q5S007	LRRK2	T1452	L1449F	1449	Missense	distal	-3	no	16.299	16.271	EPSD;PhosphoSitePlus	COSMIC	15.080	Down-regulation
TKL_LRRK_LRRK2_ST	Q5S007	LRRK2	Q5S007	LRRK2	S1457	V1450I	1450	Missense	distal	-7	no	16.050	14.661	EPSD;PhosphoSitePlus	COSMIC;GDSC	15.080	Loss
TKL_LRRK_LRRK2_ST	Q5S007	LRRK2	Q5S007	LRRK2	S1457	D1458G	1458	Missense	proximal	1	no	16.050	16.004	EPSD;PhosphoSitePlus	COSMIC	15.080	Down-regulation
TKL_LRRK_LRRK2_ST	Q5S007	LRRK2	Q5S007	LRRK2	T1491	T1491I	1491	Missense	central	0	yes	17.116	0.000	EPSD;PhosphoSitePlus	COSMIC	15.080	Loss
TKL_LRRK_LRRK2_ST	Q5S007	LRRK2	Q5S007	LRRK2	T1491	E1493A	1493	Missense	proximal	2	no	17.116	16.913	EPSD;PhosphoSitePlus	COSMIC	15.080	Down-regulation
TKL_LRRK_LRRK2_ST	Q5S007	LRRK2	Q5S007	LRRK2	T1503	I1505M	1505	Missense	proximal	2	no	16.958	17.139	EPSD;PhosphoSitePlus	COSMIC	15.080	Up-regulation
TKL_LRRK_LRRK2_ST	Q5S007	LRRK2	Q5S007	LRRK2	S1508	I1505M	1505	Missense	distal	-3	no	16.245	15.975	EPSD;PhosphoSitePlus	COSMIC	15.080	Down-regulation
TKL_LRRK_LRRK2_ST	Q5S007	LRRK2	Q5S007	LRRK2	S1508	D1515V	1515	Missense	distal	7	no	16.245	16.147	EPSD;PhosphoSitePlus	COSMIC	15.080	Down-regulation
TKL_LRRK_LRRK2_ST	Q5S007	LRRK2	Q5S007	LRRK2	S1536	E1537K	1537	Missense	proximal	1	no	16.428	16.641	EPSD;PhosphoSitePlus	COSMIC	15.080	Up-regulation
TKL_LRRK_LRRK2_ST	Q5S007	LRRK2	Q5S007	LRRK2	T1612	I1606T	1606	Missense	distal	-6	no	19.531	17.184	EPSD;PhosphoSitePlus	COSMIC	15.080	Down-regulation
TKL_LRRK_LRRK2_ST	Q5S007	LRRK2	Q5S007	LRRK2	S1647	L1653I	1653	Missense	distal	6	no	16.945	16.805	EPSD;PhosphoSitePlus	COSMIC	15.080	Down-regulation
TKL_LRRK_LRRK2_ST	Q5S007	LRRK2	Q5S007	LRRK2	S1647	Q1648P	1648	Missense	proximal	1	no	16.945	17.054	EPSD;PhosphoSitePlus	COSMIC;GDSC;CCLE	15.080	Up-regulation
TKL_LRRK_LRRK2_ST	Q5S007	LRRK2	Q5S007	LRRK2	S1721	L1720F	1720	Missense	proximal	-1	no	15.528	14.501	EPSD	COSMIC	15.080	Loss
TKL_LRRK_LRRK2_ST	Q5S007	LRRK2	Q5S007	LRRK2	S1721	I1715F	1715	Missense	distal	-6	no	15.528	15.201	EPSD	COSMIC	15.080	Down-regulation
TKL_LRRK_LRRK2_ST	Q5S007	LRRK2	Q5S007	LRRK2	S1721	E1714D	1714	Missense	distal	-7	no	15.528	16.226	EPSD	COSMIC	15.080	Up-regulation
TKL_LRRK_LRRK2_ST	Q5S007	LRRK2	Q5S007	LRRK2	S1721	P1717L	1717	Missense	distal	-4	no	15.528	14.475	EPSD	COSMIC	15.080	Loss
TKL_LRRK_LRRK2_ST	Q5S007	LRRK2	Q5S007	LRRK2	S1721	Y1718C	1718	Missense	distal	-3	no	15.528	15.479	EPSD	COSMIC	15.080	Down-regulation
TKL_LRRK_LRRK2_ST	Q5S007	LRRK2	Q5S007	LRRK2	S1721	R1725G	1725	Missense	distal	4	no	15.528	14.436	EPSD	COSMIC	15.080	Loss
TKL_LRRK_LRRK2_ST	Q5S007	LRRK2	Q5S007	LRRK2	T1849	A1856V	1856	Missense	distal	7	no	17.939	17.909	EPSD;PhosphoSitePlus	COSMIC	15.080	Down-regulation
TKL_LRRK_LRRK2_ST	Q5S007	LRRK2	Q5S007	LRRK2	T1849	I1852V	1852	Missense	distal	3	no	17.939	17.822	EPSD;PhosphoSitePlus	COSMIC	15.080	Down-regulation
TKL_LRRK_LRRK2_ST	Q5S007	LRRK2	Q5S007	LRRK2	T1849	S1853F	1853	Missense	distal	4	no	17.939	16.824	EPSD;PhosphoSitePlus	COSMIC	15.080	Down-regulation
TKL_LRRK_LRRK2_ST	Q5S007	LRRK2	Q5S007	LRRK2	T1849	T1849N	1849	Missense	central	0	yes	17.939	0.000	EPSD;PhosphoSitePlus	COSMIC	15.080	Loss
TKL_LRRK_LRRK2_ST	Q5S007	LRRK2	Q5S007	LRRK2	S1853	A1856V	1856	Missense	distal	3	no	17.287	17.103	EPSD;PhosphoSitePlus	COSMIC	15.080	Down-regulation
TKL_LRRK_LRRK2_ST	Q5S007	LRRK2	Q5S007	LRRK2	S1853	I1852V	1852	Missense	proximal	-1	no	17.287	17.089	EPSD;PhosphoSitePlus	COSMIC	15.080	Down-regulation
TKL_LRRK_LRRK2_ST	Q5S007	LRRK2	Q5S007	LRRK2	S1853	S1853F	1853	Missense	central	0	yes	17.287	0.000	EPSD;PhosphoSitePlus	COSMIC	15.080	Loss
TKL_LRRK_LRRK2_ST	Q5S007	LRRK2	Q5S007	LRRK2	S1853	T1849N	1849	Missense	distal	-4	no	17.287	17.815	EPSD;PhosphoSitePlus	COSMIC	15.080	Up-regulation
TKL_LRRK_LRRK2_ST	Q5S007	LRRK2	Q5S007	LRRK2	T1912	I1907V	1907	Missense	distal	-5	no	17.371	17.239	EPSD;PhosphoSitePlus	COSMIC	15.080	Down-regulation
TKL_LRRK_LRRK2_ST	Q5S007	LRRK2	Q5S007	LRRK2	T1912	L1914P	1914	Missense	proximal	2	no	17.371	16.925	EPSD;PhosphoSitePlus	COSMIC	15.080	Down-regulation
TKL_LRRK_LRRK2_ST	Q5S007	LRRK2	Q5S007	LRRK2	S1913	I1907V	1907	Missense	distal	-6	no	19.825	19.061	EPSD;PhosphoSitePlus	COSMIC	15.080	Down-regulation
TKL_LRRK_LRRK2_ST	Q5S007	LRRK2	Q5S007	LRRK2	S1913	L1914P	1914	Missense	proximal	1	no	19.825	19.729	EPSD;PhosphoSitePlus	COSMIC	15.080	Down-regulation
TKL_LRRK_LRRK2_ST	Q5S007	LRRK2	Q5S007	LRRK2	S1913	T1912S	1912	Missense	proximal	-1	no	19.825	19.610	EPSD;PhosphoSitePlus	COSMIC	15.080	Down-regulation
TKL_LRRK_LRRK2_ST	Q5S007	LRRK2	Q5S007	LRRK2	T1967	R1968K	1968	Missense	proximal	1	no	17.155	17.219	EPSD;PhosphoSitePlus	COSMIC	15.080	Up-regulation
TKL_LRRK_LRRK2_ST	Q5S007	LRRK2	Q5S007	LRRK2	T1969	A1975V	1975	Missense	distal	6	no	18.241	18.418	EPSD;PhosphoSitePlus	COSMIC;GDSC;CCLE	15.080	Up-regulation
TKL_LRRK_LRRK2_ST	Q5S007	LRRK2	Q5S007	LRRK2	T1969	R1968K	1968	Missense	proximal	-1	no	18.241	17.962	EPSD;PhosphoSitePlus	COSMIC	15.080	Down-regulation
TKL_LRRK_LRRK2_ST	Q5S007	LRRK2	Q5S007	LRRK2	T2031	R2026K	2026	Missense	distal	-5	no	18.012	17.948	PhosphoSitePlus;EPSD	COSMIC	15.080	Down-regulation
TKL_LRRK_LRRK2_ST	Q5S007	LRRK2	Q5S007	LRRK2	T2031	C2024R	2024	Missense	distal	-7	no	18.012	18.928	PhosphoSitePlus;EPSD	COSMIC	15.080	Up-regulation
TKL_LRRK_LRRK2_ST	Q5S007	LRRK2	Q5S007	LRRK2	T2031	E2033D	2033	Missense	proximal	2	no	18.012	17.798	PhosphoSitePlus;EPSD	COSMIC	15.080	Down-regulation
TKL_LRRK_LRRK2_ST	Q5S007	LRRK2	Q5S007	LRRK2	T2031	G2028R	2028	Missense	distal	-3	no	18.012	17.847	PhosphoSitePlus;EPSD	COSMIC;GDSC;CCLE	15.080	Down-regulation
TKL_LRRK_LRRK2_ST	Q5S007	LRRK2	Q5S007	LRRK2	T2031	K2030Q	2030	Missense	proximal	-1	no	18.012	17.903	PhosphoSitePlus;EPSD	COSMIC	15.080	Down-regulation
TKL_LRRK_LRRK2_ST	Q5S007	LRRK2	Q5S007	LRRK2	T2035	E2033D	2033	Missense	proximal	-2	no	16.598	16.504	EPSD;PhosphoSitePlus	COSMIC	15.080	Down-regulation
TKL_LRRK_LRRK2_ST	Q5S007	LRRK2	Q5S007	LRRK2	T2035	R2039H	2039	Missense	distal	4	no	16.598	15.740	EPSD;PhosphoSitePlus	COSMIC	15.080	Down-regulation
TKL_LRRK_LRRK2_ST	Q5S007	LRRK2	Q5S007	LRRK2	T2035	A2040V	2040	Missense	distal	5	no	16.598	16.931	EPSD;PhosphoSitePlus	COSMIC	15.080	Up-regulation
TKL_LRRK_LRRK2_ST	Q5S007	LRRK2	Q5S007	LRRK2	T2035	G2028R	2028	Missense	distal	-7	no	16.598	17.201	EPSD;PhosphoSitePlus	COSMIC;GDSC;CCLE	15.080	Up-regulation
TKL_LRRK_LRRK2_ST	Q5S007	LRRK2	Q5S007	LRRK2	T2035	K2030Q	2030	Missense	distal	-5	no	16.598	16.685	EPSD;PhosphoSitePlus	COSMIC	15.080	Up-regulation
TKL_LRRK_LRRK2_ST	Q5S007	LRRK2	Q5S007	LRRK2	S2257	K2255M	2255	Missense	proximal	-2	no	17.369	17.306	EPSD;PhosphoSitePlus	COSMIC	15.080	Down-regulation
TKL_LRRK_LRRK2_ST	Q5S007	LRRK2	Q5S007	LRRK2	S2257	Q2259H	2259	Missense	proximal	2	no	17.369	17.532	EPSD;PhosphoSitePlus	COSMIC	15.080	Up-regulation
TKL_LRRK_LRRK2_ST	Q5S007	LRRK2	Q5S007	LRRK2	T2460	G2464E	2464	Missense	distal	4	no	14.172	15.098	EPSD	COSMIC	15.080	Gain
TKL_LRRK_LRRK2_ST	Q5S007	LRRK2	Q5S007	LRRK2	T2483	N2476T	2476	Missense	distal	-7	no	19.727	18.919	EPSD;PhosphoSitePlus	COSMIC	15.080	Down-regulation
TKL_LRRK_LRRK2_ST	Q5S007	LRRK2	Q5S007	LRRK2	T2483	T2483I	2483	Missense	central	0	yes	19.727	0.000	EPSD;PhosphoSitePlus	COSMIC	15.080	Loss
TKL_LRRK_LRRK2_ST	Q5S007	LRRK2	Q5S007	LRRK2	T2483	T2480I	2480	Missense	distal	-3	no	19.727	19.874	EPSD;PhosphoSitePlus	COSMIC	15.080	Up-regulation
TKL_LRRK_LRRK2_ST	O75061	DNAJC6	Q5S007	LRRK2	T60	V56F	56	Missense	distal	-4	no	14.480	15.583	EPSD	COSMIC	15.080	Gain
TKL_LRRK_LRRK2_ST	O75061	DNAJC6	Q5S007	LRRK2	S563	R562H	562	Missense	proximal	-1	no	15.673	14.910	EPSD	COSMIC	15.080	Loss
TKL_LRRK_LRRK2_ST	O75061	DNAJC6	Q5S007	LRRK2	S563	S566P	566	Missense	distal	3	no	15.673	15.554	EPSD	COSMIC	15.080	Down-regulation
TKL_LRRK_LRRK2_ST	O75061	DNAJC6	Q5S007	LRRK2	S563	T567P	567	Missense	distal	4	no	15.673	14.637	EPSD	COSMIC	15.080	Loss
TKL_LRRK_LRRK2_ST	O75061	DNAJC6	Q5S007	LRRK2	S563	R561C	561	Missense	proximal	-2	no	15.673	15.380	EPSD	COSMIC	15.080	Down-regulation
TKL_LRRK_LRRK2_ST	O75061	DNAJC6	Q5S007	LRRK2	S570	S566P	566	Missense	distal	-4	no	17.746	18.358	PhosphoSitePlus	COSMIC	15.080	Up-regulation
TKL_LRRK_LRRK2_ST	O75061	DNAJC6	Q5S007	LRRK2	S570	T567P	567	Missense	distal	-3	no	17.746	17.967	PhosphoSitePlus	COSMIC	15.080	Up-regulation
TKL_LRRK_LRRK2_ST	O75061	DNAJC6	Q5S007	LRRK2	S708	A713S	713	Missense	distal	5	no	16.869	16.503	EPSD	COSMIC	15.080	Down-regulation
TKL_LRRK_LRRK2_ST	O75061	DNAJC6	Q5S007	LRRK2	S708	S709I	709	Missense	proximal	1	no	16.869	17.087	EPSD	COSMIC	15.080	Up-regulation
TKL_LRRK_LRRK2_ST	O75061	DNAJC6	Q5S007	LRRK2	S708	G702A	702	Missense	distal	-6	no	16.869	17.373	EPSD	COSMIC	15.080	Up-regulation
TKL_LRRK_LRRK2_ST	O75061	DNAJC6	Q5S007	LRRK2	S708	P715L	715	Missense	distal	7	no	16.869	16.844	EPSD	COSMIC	15.080	Down-regulation
TKL_LRRK_LRRK2_ST	O75061	DNAJC6	Q5S007	LRRK2	S708	S708R	708	Missense	central	0	yes	16.869	0.000	EPSD	COSMIC	15.080	Loss
TKL_LRRK_LRRK2_ST	O75061	DNAJC6	Q5S007	LRRK2	S708	G701D	701	Missense	distal	-7	no	16.869	17.256	EPSD	COSMIC;GDSC;CCLE	15.080	Up-regulation
TKL_LRRK_LRRK2_ST	O75061	DNAJC6	Q5S007	LRRK2	S708	G701V	701	Missense	distal	-7	no	16.869	17.147	EPSD	COSMIC	15.080	Up-regulation
TKL_LRRK_LRRK2_ST	O75061	DNAJC6	Q5S007	LRRK2	S708	A713V	713	Missense	distal	5	no	16.869	17.202	EPSD	COSMIC;GDSC;CCLE	15.080	Up-regulation
TKL_LRRK_LRRK2_ST	O75061	DNAJC6	Q5S007	LRRK2	S708	Q711H	711	Missense	distal	3	no	16.869	16.747	EPSD	COSMIC	15.080	Down-regulation
TKL_LRRK_LRRK2_ST	O75061	DNAJC6	Q5S007	LRRK2	S708	P705L	705	Missense	distal	-3	no	16.869	16.803	EPSD	COSMIC	15.080	Down-regulation
TKL_LRRK_LRRK2_ST	O75061	DNAJC6	Q5S007	LRRK2	S745	S744Y	744	Missense	proximal	-1	no	14.825	15.334	EPSD	COSMIC	15.080	Gain
TKL_LRRK_LRRK2_ST	O75061	DNAJC6	Q5S007	LRRK2	S745	S744L	744	Missense	proximal	-1	no	14.825	15.905	EPSD	COSMIC	15.080	Gain
TKL_LRRK_LRRK2_ST	P15311	EZR	Q5S007	LRRK2	T548	H554R	554	Missense	distal	6	no	14.807	15.327	EPSD	COSMIC	15.080	Gain
TKL_LRRK_LRRK2_ST	P04637	TP53	Q5S007	LRRK2	S106	K101R	101	Missense	distal	-5	no	15.023	15.087	EPSD	COSMIC	15.080	Gain
TKL_LRRK_LRRK2_ST	P04637	TP53	Q5S007	LRRK2	S106	T102P	102	Missense	distal	-4	no	15.023	15.308	EPSD	COSMIC	15.080	Gain
TKL_LRRK_LRRK2_ST	P04637	TP53	Q5S007	LRRK2	S106	L111M	111	Missense	distal	5	no	15.023	15.140	EPSD	COSMIC	15.080	Gain
TKL_LRRK_LRRK2_ST	P04637	TP53	Q5S007	LRRK2	S106	S99P	99	Missense	distal	-7	no	15.023	15.398	EPSD	COSMIC	15.080	Gain
TKL_LRRK_LRRK2_ST	P04637	TP53	Q5S007	LRRK2	S106	Q104H	104	Missense	proximal	-2	no	15.023	15.450	EPSD	COSMIC	15.080	Gain
TKL_LRRK_LRRK2_ST	P04637	TP53	Q5S007	LRRK2	T304	S303C	303	Missense	proximal	-1	no	17.200	16.515	EPSD;PhosphoSitePlus	COSMIC	15.080	Down-regulation
TKL_LRRK_LRRK2_ST	P04637	TP53	Q5S007	LRRK2	T304	S303F	303	Missense	proximal	-1	no	17.200	17.254	EPSD;PhosphoSitePlus	COSMIC	15.080	Up-regulation
TKL_LRRK_LRRK2_ST	P04637	TP53	Q5S007	LRRK2	T304	P301L	301	Missense	distal	-3	no	17.200	17.133	EPSD;PhosphoSitePlus	COSMIC	15.080	Down-regulation
TKL_LRRK_LRRK2_ST	P04637	TP53	Q5S007	LRRK2	T304	K305T	305	Missense	proximal	1	no	17.200	16.845	EPSD;PhosphoSitePlus	COSMIC	15.080	Down-regulation
TKL_LRRK_LRRK2_ST	P04637	TP53	Q5S007	LRRK2	T304	P300L	300	Missense	distal	-4	no	17.200	16.147	EPSD;PhosphoSitePlus	COSMIC	15.080	Down-regulation
TKL_LRRK_LRRK2_ST	P04637	TP53	Q5S007	LRRK2	T304	N310T	310	Missense	distal	6	no	17.200	17.428	EPSD;PhosphoSitePlus	COSMIC	15.080	Up-regulation
TKL_LRRK_LRRK2_ST	P04637	TP53	Q5S007	LRRK2	T304	T304N	304	Missense	central	0	yes	17.200	0.000	EPSD;PhosphoSitePlus	COSMIC	15.080	Loss
TKL_LRRK_LRRK2_ST	P04637	TP53	Q5S007	LRRK2	T304	H297P	297	Missense	distal	-7	no	17.200	17.594	EPSD;PhosphoSitePlus	COSMIC	15.080	Up-regulation
TKL_LRRK_LRRK2_ST	P04637	TP53	Q5S007	LRRK2	T304	P309S	309	Missense	distal	5	no	17.200	16.712	EPSD;PhosphoSitePlus	COSMIC;GDSC;CCLE	15.080	Down-regulation
TKL_LRRK_LRRK2_ST	P04637	TP53	Q5S007	LRRK2	T304	G302E	302	Missense	proximal	-2	no	17.200	16.952	EPSD;PhosphoSitePlus	COSMIC	15.080	Down-regulation
TKL_LRRK_LRRK2_ST	P04637	TP53	Q5S007	LRRK2	T304	N310L	310	Missense	distal	6	no	17.200	18.028	EPSD;PhosphoSitePlus	COSMIC	15.080	Up-regulation
TKL_LRRK_LRRK2_ST	P04637	TP53	Q5S007	LRRK2	T304	K305N	305	Missense	proximal	1	no	17.200	16.912	EPSD;PhosphoSitePlus	COSMIC	15.080	Down-regulation
TKL_LRRK_LRRK2_ST	P04637	TP53	Q5S007	LRRK2	T304	H297Y	297	Missense	distal	-7	no	17.200	16.566	EPSD;PhosphoSitePlus	COSMIC	15.080	Down-regulation
TKL_LRRK_LRRK2_ST	P04637	TP53	Q5S007	LRRK2	T304	P300S	300	Missense	distal	-4	no	17.200	16.588	EPSD;PhosphoSitePlus	COSMIC	15.080	Down-regulation
TKL_LRRK_LRRK2_ST	P04637	TP53	Q5S007	LRRK2	T304	S303N	303	Missense	proximal	-1	no	17.200	17.012	EPSD;PhosphoSitePlus	COSMIC	15.080	Down-regulation
TKL_LRRK_LRRK2_ST	P04637	TP53	Q5S007	LRRK2	T304	N311Y	311	Missense	distal	7	no	17.200	17.175	EPSD;PhosphoSitePlus	COSMIC	15.080	Down-regulation
TKL_LRRK_LRRK2_ST	P04637	TP53	Q5S007	LRRK2	T304	T304A	304	Missense	central	0	yes	17.200	0.000	EPSD;PhosphoSitePlus	COSMIC	15.080	Loss
TKL_LRRK_LRRK2_ST	P04637	TP53	Q5S007	LRRK2	T304	L299P	299	Missense	distal	-5	no	17.200	17.191	EPSD;PhosphoSitePlus	COSMIC	15.080	Down-regulation
TKL_LRRK_LRRK2_ST	P04637	TP53	Q5S007	LRRK2	T304	R306P	306	Missense	proximal	2	no	17.200	16.179	EPSD;PhosphoSitePlus	COSMIC	15.080	Down-regulation
TKL_LRRK_LRRK2_ST	P04637	TP53	Q5S007	LRRK2	T304	A307T	307	Missense	distal	3	no	17.200	16.989	EPSD;PhosphoSitePlus	COSMIC	15.080	Down-regulation
TKL_LRRK_LRRK2_ST	P04637	TP53	Q5S007	LRRK2	T304	N311K	311	Missense	distal	7	no	17.200	17.120	EPSD;PhosphoSitePlus	COSMIC	15.080	Down-regulation
TKL_LRRK_LRRK2_ST	P04637	TP53	Q5S007	LRRK2	T304	P300R	300	Missense	distal	-4	no	17.200	16.745	EPSD;PhosphoSitePlus	COSMIC	15.080	Down-regulation
TKL_LRRK_LRRK2_ST	P04637	TP53	Q5S007	LRRK2	T304	K305E	305	Missense	proximal	1	no	17.200	16.987	EPSD;PhosphoSitePlus	COSMIC	15.080	Down-regulation
TKL_LRRK_LRRK2_ST	P04637	TP53	Q5S007	LRRK2	T304	P301S	301	Missense	distal	-3	no	17.200	17.201	EPSD;PhosphoSitePlus	COSMIC	15.080	Up-regulation
TKL_LRRK_LRRK2_ST	P04637	TP53	Q5S007	LRRK2	T304	N310H	310	Missense	distal	6	no	17.200	17.091	EPSD;PhosphoSitePlus	COSMIC	15.080	Down-regulation
TKL_LRRK_LRRK2_ST	P04637	TP53	Q5S007	LRRK2	T304	P300A	300	Missense	distal	-4	no	17.200	16.544	EPSD;PhosphoSitePlus	COSMIC	15.080	Down-regulation
TKL_LRRK_LRRK2_ST	P04637	TP53	Q5S007	LRRK2	T304	R306Q	306	Missense	proximal	2	no	17.200	16.625	EPSD;PhosphoSitePlus	COSMIC	15.080	Down-regulation
TKL_LRRK_LRRK2_ST	P04637	TP53	Q5S007	LRRK2	T304	K305R	305	Missense	proximal	1	no	17.200	17.136	EPSD;PhosphoSitePlus	COSMIC	15.080	Down-regulation
TKL_LRRK_LRRK2_ST	P04637	TP53	Q5S007	LRRK2	T304	E298V	298	Missense	distal	-6	no	17.200	16.443	EPSD;PhosphoSitePlus	COSMIC	15.080	Down-regulation
TKL_LRRK_LRRK2_ST	P04637	TP53	Q5S007	LRRK2	T304	L299V	299	Missense	distal	-5	no	17.200	17.112	EPSD;PhosphoSitePlus	COSMIC	15.080	Down-regulation
TKL_LRRK_LRRK2_ST	P04637	TP53	Q5S007	LRRK2	T304	S303T	303	Missense	proximal	-1	no	17.200	17.414	EPSD;PhosphoSitePlus	COSMIC	15.080	Up-regulation
TKL_LRRK_LRRK2_ST	P04637	TP53	Q5S007	LRRK2	T304	L308M	308	Missense	distal	4	no	17.200	16.790	EPSD;PhosphoSitePlus	COSMIC	15.080	Down-regulation
TKL_LRRK_LRRK2_ST	P04637	TP53	Q5S007	LRRK2	T304	N311H	311	Missense	distal	7	no	17.200	17.205	EPSD;PhosphoSitePlus	COSMIC	15.080	Up-regulation
TKL_LRRK_LRRK2_ST	P04637	TP53	Q5S007	LRRK2	T304	L308V	308	Missense	distal	4	no	17.200	16.475	EPSD;PhosphoSitePlus	COSMIC	15.080	Down-regulation
TKL_LRRK_LRRK2_ST	P04637	TP53	Q5S007	LRRK2	T304	E298Q	298	Missense	distal	-6	no	17.200	16.753	EPSD;PhosphoSitePlus	COSMIC	15.080	Down-regulation
TKL_LRRK_LRRK2_ST	P04637	TP53	Q5S007	LRRK2	T304	E298D	298	Missense	distal	-6	no	17.200	17.128	EPSD;PhosphoSitePlus	COSMIC	15.080	Down-regulation
TKL_LRRK_LRRK2_ST	P04637	TP53	Q5S007	LRRK2	T304	T304I	304	Missense	central	0	yes	17.200	0.000	EPSD;PhosphoSitePlus	COSMIC	15.080	Loss
TKL_LRRK_LRRK2_ST	P04637	TP53	Q5S007	LRRK2	T304	E298K	298	Missense	distal	-6	no	17.200	16.130	EPSD;PhosphoSitePlus	COSMIC	15.080	Down-regulation
TKL_LRRK_LRRK2_ST	P04637	TP53	Q5S007	LRRK2	T304	N310D	310	Missense	distal	6	no	17.200	17.296	EPSD;PhosphoSitePlus	COSMIC	15.080	Up-regulation
TKL_LRRK_LRRK2_ST	P04637	TP53	Q5S007	LRRK2	T304	N311D	311	Missense	distal	7	no	17.200	17.223	EPSD;PhosphoSitePlus	COSMIC	15.080	Up-regulation
TKL_LRRK_LRRK2_ST	P04637	TP53	Q5S007	LRRK2	T304	P301A	301	Missense	distal	-3	no	17.200	17.116	EPSD;PhosphoSitePlus	COSMIC	15.080	Down-regulation
TKL_LRRK_LRRK2_ST	P04637	TP53	Q5S007	LRRK2	T304	P301Q	301	Missense	distal	-3	no	17.200	16.718	EPSD;PhosphoSitePlus	COSMIC	15.080	Down-regulation
TKL_LRRK_LRRK2_ST	P04637	TP53	Q5S007	LRRK2	T304	P309R	309	Missense	distal	5	no	17.200	16.914	EPSD;PhosphoSitePlus	COSMIC	15.080	Down-regulation
TKL_LRRK_LRRK2_ST	P04637	TP53	Q5S007	LRRK2	T304	H297N	297	Missense	distal	-7	no	17.200	18.333	EPSD;PhosphoSitePlus	COSMIC	15.080	Up-regulation
TKL_LRRK_LRRK2_ST	P04637	TP53	Q5S007	LRRK2	T304	G302R	302	Missense	proximal	-2	no	17.200	17.264	EPSD;PhosphoSitePlus	COSMIC	15.080	Up-regulation
TKL_LRRK_LRRK2_ST	P04637	TP53	Q5S007	LRRK2	T304	E298A	298	Missense	distal	-6	no	17.200	16.387	EPSD;PhosphoSitePlus	COSMIC	15.080	Down-regulation
TKL_LRRK_LRRK2_ST	P04637	TP53	Q5S007	LRRK2	T304	A307S	307	Missense	distal	3	no	17.200	17.116	EPSD;PhosphoSitePlus	COSMIC	15.080	Down-regulation
TKL_LRRK_LRRK2_ST	P04637	TP53	Q5S007	LRRK2	T304	E298G	298	Missense	distal	-6	no	17.200	15.883	EPSD;PhosphoSitePlus	COSMIC	15.080	Down-regulation
TKL_LRRK_LRRK2_ST	P04637	TP53	Q5S007	LRRK2	T377	K370N	370	Missense	distal	-7	no	15.470	15.398	PhosphoSitePlus;EPSD	COSMIC	15.080	Down-regulation
TKL_LRRK_LRRK2_ST	P04637	TP53	Q5S007	LRRK2	T377	L383F	383	Missense	distal	6	no	15.470	14.468	PhosphoSitePlus;EPSD	COSMIC	15.080	Loss
TKL_LRRK_LRRK2_ST	P04637	TP53	Q5S007	LRRK2	T377	R379H	379	Missense	proximal	2	no	15.470	15.058	PhosphoSitePlus;EPSD	COSMIC	15.080	Loss
TKL_LRRK_LRRK2_ST	P04637	TP53	Q5S007	LRRK2	T377	S376T	376	Missense	proximal	-1	no	15.470	15.684	PhosphoSitePlus;EPSD	COSMIC	15.080	Up-regulation
TKL_LRRK_LRRK2_ST	P04637	TP53	Q5S007	LRRK2	T377	H380Y	380	Missense	distal	3	no	15.470	15.449	PhosphoSitePlus;EPSD	COSMIC	15.080	Down-regulation
TKL_LRRK_LRRK2_ST	P04637	TP53	Q5S007	LRRK2	T377	T377I	377	Missense	central	0	yes	15.470	0.000	PhosphoSitePlus;EPSD	COSMIC	15.080	Loss
TKL_LRRK_LRRK2_ST	P04637	TP53	Q5S007	LRRK2	T377	S378F	378	Missense	proximal	1	no	15.470	15.562	PhosphoSitePlus;EPSD	COSMIC	15.080	Up-regulation
TKL_LRRK_LRRK2_ST	P04637	TP53	Q5S007	LRRK2	T377	K370Q	370	Missense	distal	-7	no	15.470	14.443	PhosphoSitePlus;EPSD	COSMIC	15.080	Loss
TKL_LRRK_LRRK2_ST	P04637	TP53	Q5S007	LRRK2	T377	K381N	381	Missense	distal	4	no	15.470	15.592	PhosphoSitePlus;EPSD	COSMIC	15.080	Up-regulation
TKL_LRRK_LRRK2_ST	P04637	TP53	Q5S007	LRRK2	T377	R379P	379	Missense	proximal	2	no	15.470	14.449	PhosphoSitePlus;EPSD	COSMIC	15.080	Loss
TKL_LRRK_LRRK2_ST	P04637	TP53	Q5S007	LRRK2	T377	M384I	384	Missense	distal	7	no	15.470	15.508	PhosphoSitePlus;EPSD	COSMIC	15.080	Up-regulation
TKL_LRRK_LRRK2_ST	P04637	TP53	Q5S007	LRRK2	T377	K373R	373	Missense	distal	-4	no	15.470	14.691	PhosphoSitePlus;EPSD	COSMIC	15.080	Loss
TKL_LRRK_LRRK2_ST	P04637	TP53	Q5S007	LRRK2	T377	S376F	376	Missense	proximal	-1	no	15.470	15.524	PhosphoSitePlus;EPSD	COSMIC	15.080	Up-regulation
TKL_LRRK_LRRK2_ST	P04637	TP53	Q5S007	LRRK2	T377	G374S	374	Missense	distal	-3	no	15.470	15.699	PhosphoSitePlus;EPSD	COSMIC	15.080	Up-regulation
TKL_LRRK_LRRK2_ST	P04637	TP53	Q5S007	LRRK2	T377	S376A	376	Missense	proximal	-1	no	15.470	16.301	PhosphoSitePlus;EPSD	COSMIC	15.080	Up-regulation
TKL_LRRK_LRRK2_ST	P04637	TP53	Q5S007	LRRK2	T377	S371P	371	Missense	distal	-6	no	15.470	15.439	PhosphoSitePlus;EPSD	COSMIC	15.080	Down-regulation
TKL_LRRK_LRRK2_ST	P62280	RPS11	Q5S007	LRRK2	T46	E49G	49	Missense	distal	3	no	18.909	18.930	PhosphoSitePlus;EPSD	COSMIC	15.080	Up-regulation
TKL_LRRK_LRRK2_ST	P62280	RPS11	Q5S007	LRRK2	T46	E49V	49	Missense	distal	3	no	18.909	18.788	PhosphoSitePlus;EPSD	COSMIC	15.080	Down-regulation
TKL_LRRK_LRRK2_ST	P62280	RPS11	Q5S007	LRRK2	T46	E49A	49	Missense	distal	3	no	18.909	18.972	PhosphoSitePlus;EPSD	COSMIC	15.080	Up-regulation
TKL_LRRK_LRRK2_ST	P62280	RPS11	Q5S007	LRRK2	T54	E49G	49	Missense	distal	-5	no	18.314	18.280	EPSD;PhosphoSitePlus	COSMIC	15.080	Down-regulation
TKL_LRRK_LRRK2_ST	P62280	RPS11	Q5S007	LRRK2	T54	P61L	61	Missense	distal	7	no	18.314	18.289	EPSD;PhosphoSitePlus	COSMIC	15.080	Down-regulation
TKL_LRRK_LRRK2_ST	P62280	RPS11	Q5S007	LRRK2	T54	E49V	49	Missense	distal	-5	no	18.314	18.162	EPSD;PhosphoSitePlus	COSMIC	15.080	Down-regulation
TKL_LRRK_LRRK2_ST	P62280	RPS11	Q5S007	LRRK2	T54	E49A	49	Missense	distal	-5	no	18.314	18.254	EPSD;PhosphoSitePlus	COSMIC	15.080	Down-regulation
TKL_LRRK_LRRK2_ST	P62280	RPS11	Q5S007	LRRK2	T78	R71Q	71	Missense	distal	-7	no	15.774	15.248	EPSD	COSMIC	15.080	Down-regulation
TKL_LRRK_LRRK2_ST	Q99683	MAP3K5	Q5S007	LRRK2	T825	I832T	832	Missense	distal	7	no	17.293	17.299	EPSD;PhosphoSitePlus	COSMIC;GDSC;CCLE	15.080	Up-regulation
TKL_LRRK_LRRK2_ST	Q99683	MAP3K5	Q5S007	LRRK2	T838	P834S	834	Missense	distal	-4	no	16.795	16.183	PhosphoSitePlus;EPSD	COSMIC	15.080	Down-regulation
TKL_LRRK_LRRK2_ST	Q99683	MAP3K5	Q5S007	LRRK2	T838	I832T	832	Missense	distal	-6	no	16.795	14.448	PhosphoSitePlus;EPSD	COSMIC;GDSC;CCLE	15.080	Loss
TKL_LRRK_LRRK2_ST	Q99683	MAP3K5	Q5S007	LRRK2	T838	G841C	841	Missense	distal	3	no	16.795	16.833	PhosphoSitePlus;EPSD	COSMIC	15.080	Up-regulation
TKL_LRRK_LRRK2_ST	Q99683	MAP3K5	Q5S007	LRRK2	S908	S906F	906	Missense	proximal	-2	no	16.292	16.563	EPSD	COSMIC	15.080	Up-regulation
TKL_LRRK_LRRK2_ST	P31749	AKT1	Q5S007	LRRK2	S122	E115K	115	Missense	distal	-7	no	14.308	15.723	EPSD	COSMIC	15.080	Gain
TKL_LRRK_LRRK2_ST	P46459	NSF	Q5S007	LRRK2	T579	E578K	578	Missense	proximal	-1	no	15.586	17.479	EPSD	COSMIC	15.080	Up-regulation
TKL_LRRK_LRRK2_ST	P46459	NSF	Q5S007	LRRK2	T579	M585L	585	Missense	distal	6	no	15.586	15.875	EPSD	COSMIC	15.080	Up-regulation
TKL_LRRK_LRRK2_ST	P46459	NSF	Q5S007	LRRK2	T645	G644W	644	Missense	proximal	-1	no	18.553	15.934	PhosphoSitePlus	COSMIC	15.080	Down-regulation
TKL_LRRK_LRRK2_ST	P46459	NSF	Q5S007	LRRK2	T645	R648C	648	Missense	distal	3	no	18.553	18.449	PhosphoSitePlus	COSMIC	15.080	Down-regulation
TKL_LRRK_LRRK2_ST	P46459	NSF	Q5S007	LRRK2	T693	R691C	691	Missense	proximal	-2	no	16.279	15.987	EPSD	COSMIC	15.080	Down-regulation
TKL_LRRK_LRRK2_ST	P62841	RPS15	Q5S007	LRRK2	T78	P73S	73	Missense	distal	-5	no	15.564	15.626	EPSD	COSMIC;GDSC	15.080	Up-regulation
TKL_LRRK_LRRK2_ST	P62841	RPS15	Q5S007	LRRK2	T78	R81L	81	Missense	distal	3	no	15.564	15.398	EPSD	COSMIC	15.080	Down-regulation
TKL_LRRK_LRRK2_ST	P62841	RPS15	Q5S007	LRRK2	T78	R81W	81	Missense	distal	3	no	15.564	15.258	EPSD	COSMIC	15.080	Down-regulation
TKL_LRRK_LRRK2_ST	P62841	RPS15	Q5S007	LRRK2	T78	D82E	82	Missense	distal	4	no	15.564	16.944	EPSD	COSMIC	15.080	Up-regulation
TKL_LRRK_LRRK2_ST	P62841	RPS15	Q5S007	LRRK2	T78	H79Y	79	Missense	proximal	1	no	15.564	15.656	EPSD	COSMIC	15.080	Up-regulation
TKL_LRRK_LRRK2_ST	P62841	RPS15	Q5S007	LRRK2	T78	K72N	72	Missense	distal	-6	no	15.564	15.826	EPSD	COSMIC	15.080	Up-regulation
TKL_LRRK_LRRK2_ST	P62841	RPS15	Q5S007	LRRK2	T101	G95D	95	Missense	distal	-6	no	14.897	16.142	EPSD	COSMIC	15.080	Gain
TKL_LRRK_LRRK2_ST	P26038	MSN	Q5S007	LRRK2	T413	D409E	409	Missense	distal	-4	no	14.935	15.596	EPSD	COSMIC	15.080	Gain
TKL_LRRK_LRRK2_ST	P26038	MSN	Q5S007	LRRK2	T425	Q430H	430	Missense	distal	5	no	14.916	15.592	EPSD	COSMIC;GDSC;CCLE	15.080	Gain
TKL_LRRK_LRRK2_ST	P26038	MSN	Q5S007	LRRK2	T539	A546S	546	Missense	distal	7	no	15.538	15.536	EPSD	COSMIC	15.080	Down-regulation
TKL_LRRK_LRRK2_ST	P10636	MAPT	Q5S007	LRRK2	T111	I108V	108	Missense	distal	-3	no	17.258	17.208	EPSD	COSMIC	15.080	Down-regulation
TKL_LRRK_LRRK2_ST	P10636	MAPT	Q5S007	LRRK2	T111	G107R	107	Missense	distal	-4	no	17.258	17.247	EPSD	COSMIC	15.080	Down-regulation
TKL_LRRK_LRRK2_ST	P10636	MAPT	Q5S007	LRRK2	T403	L410F	410	Missense	distal	7	no	18.291	18.325	EPSD	COSMIC	15.080	Up-regulation
TKL_LRRK_LRRK2_ST	P10636	MAPT	Q5S007	LRRK2	T403	R398C	398	Missense	distal	-5	no	18.291	18.147	EPSD	COSMIC	15.080	Down-regulation
TKL_LRRK_LRRK2_ST	P10636	MAPT	Q5S007	LRRK2	T403	S396F	396	Missense	distal	-7	no	18.291	18.222	EPSD	COSMIC	15.080	Down-regulation
TKL_LRRK_LRRK2_ST	P10636	MAPT	Q5S007	LRRK2	T416	L410F	410	Missense	distal	-6	no	14.926	15.118	EPSD	COSMIC	15.080	Gain
TKL_LRRK_LRRK2_ST	P10636	MAPT	Q5S007	LRRK2	S447	S443Y	443	Missense	distal	-4	no	15.455	14.097	EPSD	COSMIC	15.080	Loss
TKL_LRRK_LRRK2_ST	P10636	MAPT	Q5S007	LRRK2	S447	S447P	447	Missense	central	0	yes	15.455	0.000	EPSD	COSMIC	15.080	Loss
TKL_LRRK_LRRK2_ST	P10636	MAPT	Q5S007	LRRK2	S447	R448Q	448	Missense	proximal	1	no	15.455	15.220	EPSD	COSMIC	15.080	Down-regulation
TKL_LRRK_LRRK2_ST	P10636	MAPT	Q5S007	LRRK2	T466	T466M	466	Missense	central	0	yes	17.500	0.000	EPSD	COSMIC;GDSC;CCLE	15.080	Loss
TKL_LRRK_LRRK2_ST	P10636	MAPT	Q5S007	LRRK2	T466	K467T	467	Missense	proximal	1	no	17.500	17.146	EPSD	COSMIC	15.080	Down-regulation
TKL_LRRK_LRRK2_ST	P10636	MAPT	Q5S007	LRRK2	S512	P506S	506	Missense	distal	-6	no	15.999	16.030	EPSD	COSMIC	15.080	Up-regulation
TKL_LRRK_LRRK2_ST	P10636	MAPT	Q5S007	LRRK2	S512	G518V	518	Missense	distal	6	no	15.999	15.901	EPSD	COSMIC	15.080	Down-regulation
TKL_LRRK_LRRK2_ST	P10636	MAPT	Q5S007	LRRK2	S512	R511C	511	Missense	proximal	-1	no	15.999	13.699	EPSD	COSMIC;CCLE	15.080	Loss
TKL_LRRK_LRRK2_ST	P10636	MAPT	Q5S007	LRRK2	S512	G509V	509	Missense	distal	-3	no	15.999	16.103	EPSD	COSMIC	15.080	Up-regulation
TKL_LRRK_LRRK2_ST	P10636	MAPT	Q5S007	LRRK2	S512	P506L	506	Missense	distal	-6	no	15.999	15.363	EPSD	COSMIC	15.080	Down-regulation
TKL_LRRK_LRRK2_ST	P10636	MAPT	Q5S007	LRRK2	T522	G521V	521	Missense	proximal	-1	no	17.917	16.327	EPSD	COSMIC	15.080	Down-regulation
TKL_LRRK_LRRK2_ST	P10636	MAPT	Q5S007	LRRK2	T522	R526H	526	Missense	distal	4	no	17.917	17.059	EPSD	COSMIC	15.080	Down-regulation
TKL_LRRK_LRRK2_ST	P10636	MAPT	Q5S007	LRRK2	T522	G518V	518	Missense	distal	-4	no	17.917	17.178	EPSD	COSMIC	15.080	Down-regulation
TKL_LRRK_LRRK2_ST	P10636	MAPT	Q5S007	LRRK2	T522	R528S	528	Missense	distal	6	no	17.917	17.813	EPSD	COSMIC	15.080	Down-regulation
TKL_LRRK_LRRK2_ST	P10636	MAPT	Q5S007	LRRK2	S531	P535Q	535	Missense	distal	4	no	13.855	15.306	EPSD	COSMIC	15.080	Gain
TKL_LRRK_LRRK2_ST	P10636	MAPT	Q5S007	LRRK2	T548	P550S	550	Missense	proximal	2	no	16.245	16.487	EPSD	COSMIC	15.080	Up-regulation
TKL_LRRK_LRRK2_ST	P10636	MAPT	Q5S007	LRRK2	T548	P553R	553	Missense	distal	5	no	16.245	15.959	EPSD	COSMIC	15.080	Down-regulation
TKL_LRRK_LRRK2_ST	P10636	MAPT	Q5S007	LRRK2	T548	P553L	553	Missense	distal	5	no	16.245	15.745	EPSD	COSMIC	15.080	Down-regulation
TKL_LRRK_LRRK2_ST	P10636	MAPT	Q5S007	LRRK2	T548	P549L	549	Missense	proximal	1	no	16.245	16.341	EPSD	COSMIC	15.080	Up-regulation
TKL_LRRK_LRRK2_ST	P10636	MAPT	Q5S007	LRRK2	T548	S555F	555	Missense	distal	7	no	16.245	16.269	EPSD	COSMIC	15.080	Up-regulation
TKL_LRRK_LRRK2_ST	P10636	MAPT	Q5S007	LRRK2	T548	P553Q	553	Missense	distal	5	no	16.245	15.344	EPSD	COSMIC	15.080	Down-regulation
TKL_LRRK_LRRK2_ST	P10636	MAPT	Q5S007	LRRK2	S554	P553R	553	Missense	proximal	-1	no	14.319	15.391	EPSD	COSMIC	15.080	Gain
TKL_LRRK_LRRK2_ST	P10636	MAPT	Q5S007	LRRK2	S558	V565M	565	Missense	distal	7	no	15.228	15.231	EPSD	COSMIC	15.080	Up-regulation
TKL_LRRK_LRRK2_ST	P10636	MAPT	Q5S007	LRRK2	S558	R559C	559	Missense	proximal	1	no	15.228	14.811	EPSD	COSMIC	15.080	Loss
TKL_LRRK_LRRK2_ST	P10636	MAPT	Q5S007	LRRK2	S558	P553R	553	Missense	distal	-5	no	15.228	15.404	EPSD	COSMIC	15.080	Up-regulation
TKL_LRRK_LRRK2_ST	P10636	MAPT	Q5S007	LRRK2	S558	P553L	553	Missense	distal	-5	no	15.228	15.237	EPSD	COSMIC	15.080	Up-regulation
TKL_LRRK_LRRK2_ST	P10636	MAPT	Q5S007	LRRK2	S558	S555F	555	Missense	distal	-3	no	15.228	15.133	EPSD	COSMIC	15.080	Down-regulation
TKL_LRRK_LRRK2_ST	P10636	MAPT	Q5S007	LRRK2	S558	P553Q	553	Missense	distal	-5	no	15.228	15.426	EPSD	COSMIC	15.080	Up-regulation
TKL_LRRK_LRRK2_ST	P10636	MAPT	Q5S007	LRRK2	S729	R723W	723	Missense	distal	-6	no	12.710	15.263	EPSD	COSMIC	15.080	Gain
TKL_LRRK_LRRK2_ST	P05067	APP	Q5S007	LRRK2	T381	E380Q	380	Missense	proximal	-1	no	16.467	18.251	EPSD	COSMIC	15.080	Up-regulation
TKL_LRRK_LRRK2_ST	P05067	APP	Q5S007	LRRK2	T381	K377R	377	Missense	distal	-4	no	16.467	15.688	EPSD	COSMIC	15.080	Down-regulation
TKL_LRRK_LRRK2_ST	P05067	APP	Q5S007	LRRK2	T381	D376G	376	Missense	distal	-5	no	16.467	16.572	EPSD	COSMIC	15.080	Up-regulation
TKL_LRRK_LRRK2_ST	P05067	APP	Q5S007	LRRK2	T381	G383W	383	Missense	proximal	2	no	16.467	14.468	EPSD	COSMIC	15.080	Loss
TKL_LRRK_LRRK2_ST	P05067	APP	Q5S007	LRRK2	T381	V375I	375	Missense	distal	-6	no	16.467	17.230	EPSD	COSMIC	15.080	Up-regulation
TKL_LRRK_LRRK2_ST	P05067	APP	Q5S007	LRRK2	T381	N386S	386	Missense	distal	5	no	16.467	15.915	EPSD	COSMIC	15.080	Down-regulation
TKL_LRRK_LRRK2_ST	P05067	APP	Q5S007	LRRK2	S441	Q436E	436	Missense	distal	-5	no	16.391	16.267	EPSD	COSMIC	15.080	Down-regulation
TKL_LRRK_LRRK2_ST	P05067	APP	Q5S007	LRRK2	S441	F435L	435	Missense	distal	-6	no	16.391	16.198	EPSD	COSMIC	15.080	Down-regulation
TKL_LRRK_LRRK2_ST	P05067	APP	Q5S007	LRRK2	T743	V742L	742	Missense	proximal	-1	no	16.869	18.235	PhosphoSitePlus	COSMIC	15.080	Up-regulation
TKL_LRRK_LRRK2_ST	P05067	APP	Q5S007	LRRK2	T743	E745K	745	Missense	proximal	2	no	16.869	17.607	PhosphoSitePlus	COSMIC	15.080	Up-regulation
TKL_LRRK_LRRK2_ST	Q13501	SQSTM1	Q5S007	LRRK2	S28	R22W	22	Missense	distal	-6	no	13.990	16.543	EPSD	COSMIC	15.080	Gain
TKL_LRRK_LRRK2_ST	Q13501	SQSTM1	Q5S007	LRRK2	T138	V135L	135	Missense	distal	-3	no	15.898	15.956	PhosphoSitePlus	COSMIC	15.080	Up-regulation
TKL_LRRK_LRRK2_ST	Q13501	SQSTM1	Q5S007	LRRK2	T138	Y140H	140	Missense	proximal	2	no	15.898	16.716	PhosphoSitePlus	COSMIC	15.080	Up-regulation
TKL_LRRK_LRRK2_ST	Q13501	SQSTM1	Q5S007	LRRK2	T164	A167T	167	Missense	distal	3	no	17.232	17.021	EPSD	COSMIC	15.080	Down-regulation
TKL_LRRK_LRRK2_ST	Q13501	SQSTM1	Q5S007	LRRK2	T164	G158D	158	Missense	distal	-6	no	17.232	18.476	EPSD	COSMIC	15.080	Up-regulation
TKL_LRRK_LRRK2_ST	Q13501	SQSTM1	Q5S007	LRRK2	T221	S226F	226	Missense	distal	5	no	15.108	15.780	EPSD	COSMIC	15.080	Up-regulation
TKL_LRRK_LRRK2_ST	Q13501	SQSTM1	Q5S007	LRRK2	T221	T221M	221	Missense	central	0	yes	15.108	0.000	EPSD	COSMIC	15.080	Loss
TKL_LRRK_LRRK2_ST	Q13501	SQSTM1	Q5S007	LRRK2	S276	E274D	274	Missense	proximal	-2	no	15.308	15.214	EPSD	COSMIC	15.080	Down-regulation
CAMK_CAMKL_QIK_SIK1_ST	Q9Y618	NCOR2	P57059	SIK1	S373	R367H	367	Missense	distal	-6	no	6.811	6.745	EPSD	COSMIC	6.412	Down-regulation
CAMK_CAMKL_QIK_SIK1_ST	Q9Y618	NCOR2	P57059	SIK1	S373	L379V	379	Missense	distal	6	no	6.811	6.600	EPSD	COSMIC	6.412	Down-regulation
CAMK_CAMKL_QIK_SIK1_ST	Q9Y618	NCOR2	P57059	SIK1	S433	E434K	434	Missense	proximal	1	no	7.081	6.859	EPSD	COSMIC	6.412	Down-regulation
CAMK_CAMKL_QIK_SIK1_ST	Q9Y618	NCOR2	P57059	SIK1	S493	R488W	488	Missense	distal	-5	no	5.997	7.504	EPSD	COSMIC	6.412	Gain
CAMK_CAMKL_QIK_SIK1_ST	Q9Y618	NCOR2	P57059	SIK1	S585	R578H	578	Missense	distal	-7	no	8.370	8.512	EPSD	COSMIC	6.412	Up-regulation
CAMK_CAMKL_QIK_SIK1_ST	Q9Y618	NCOR2	P57059	SIK1	S585	R578C	578	Missense	distal	-7	no	8.370	8.341	EPSD	COSMIC	6.412	Down-regulation
CAMK_CAMKL_QIK_SIK1_ST	Q9Y618	NCOR2	P57059	SIK1	S585	A587T	587	Missense	proximal	2	no	8.370	8.248	EPSD	COSMIC	6.412	Down-regulation
CAMK_CAMKL_QIK_SIK1_ST	Q9Y618	NCOR2	P57059	SIK1	S592	Q599K	599	Missense	distal	7	no	7.228	7.403	EPSD	COSMIC	6.412	Up-regulation
CAMK_CAMKL_QIK_SIK1_ST	Q9Y618	NCOR2	P57059	SIK1	S592	T597A	597	Missense	distal	5	no	7.228	7.170	EPSD	COSMIC	6.412	Down-regulation
CAMK_CAMKL_QIK_SIK1_ST	Q9Y618	NCOR2	P57059	SIK1	S592	T597I	597	Missense	distal	5	no	7.228	7.117	EPSD	COSMIC	6.412	Down-regulation
CAMK_CAMKL_QIK_SIK1_ST	Q9Y618	NCOR2	P57059	SIK1	S592	A587T	587	Missense	distal	-5	no	7.228	7.666	EPSD	COSMIC	6.412	Up-regulation
CAMK_CAMKL_QIK_SIK1_ST	Q9Y618	NCOR2	P57059	SIK1	S601	A602V	602	Missense	proximal	1	no	6.617	6.451	EPSD	COSMIC	6.412	Down-regulation
CAMK_CAMKL_QIK_SIK1_ST	Q9Y618	NCOR2	P57059	SIK1	S601	Q599K	599	Missense	proximal	-2	no	6.617	7.495	EPSD	COSMIC	6.412	Up-regulation
CAMK_CAMKL_QIK_SIK1_ST	Q9Y618	NCOR2	P57059	SIK1	S601	T597A	597	Missense	distal	-4	no	6.617	5.050	EPSD	COSMIC	6.412	Loss
CAMK_CAMKL_QIK_SIK1_ST	Q9Y618	NCOR2	P57059	SIK1	S601	T597I	597	Missense	distal	-4	no	6.617	4.090	EPSD	COSMIC	6.412	Loss
CAMK_CAMKL_QIK_SIK1_ST	Q9Y618	NCOR2	P57059	SIK1	S601	E603K	603	Missense	proximal	2	no	6.617	6.562	EPSD	COSMIC	6.412	Down-regulation
CAMK_CAMKL_QIK_SIK1_ST	Q9Y618	NCOR2	P57059	SIK1	T867	T867A	867	Missense	central	0	yes	8.219	0.000	EPSD	COSMIC	6.412	Loss
CAMK_CAMKL_QIK_SIK1_ST	Q9Y618	NCOR2	P57059	SIK1	T867	E868G	868	Missense	proximal	1	no	8.219	7.753	EPSD	COSMIC	6.412	Down-regulation
CAMK_CAMKL_QIK_SIK1_ST	Q9Y618	NCOR2	P57059	SIK1	T867	T867M	867	Missense	central	0	yes	8.219	0.000	EPSD	COSMIC;GDSC;CCLE	6.412	Loss
CAMK_CAMKL_QIK_SIK1_ST	Q9Y618	NCOR2	P57059	SIK1	T867	E860A	860	Missense	distal	-7	no	8.219	8.347	EPSD	COSMIC	6.412	Up-regulation
CAMK_CAMKL_QIK_SIK1_ST	Q9Y618	NCOR2	P57059	SIK1	T867	E868K	868	Missense	proximal	1	no	8.219	7.997	EPSD	COSMIC	6.412	Down-regulation
CAMK_CAMKL_QIK_SIK1_ST	Q9Y618	NCOR2	P57059	SIK1	T867	A870G	870	Missense	distal	3	no	8.219	8.391	EPSD	COSMIC	6.412	Up-regulation
CAMK_CAMKL_QIK_SIK1_ST	Q9Y618	NCOR2	P57059	SIK1	S1018	S1017N	1017	Missense	proximal	-1	no	9.929	9.768	EPSD	COSMIC	6.412	Down-regulation
CAMK_CAMKL_QIK_SIK1_ST	Q9Y618	NCOR2	P57059	SIK1	S1018	P1015T	1015	Missense	distal	-3	no	9.929	10.566	EPSD	COSMIC	6.412	Up-regulation
CAMK_CAMKL_QIK_SIK1_ST	Q9Y618	NCOR2	P57059	SIK1	S1018	A1011T	1011	Missense	distal	-7	no	9.929	9.737	EPSD	COSMIC;CCLE	6.412	Down-regulation
CAMK_CAMKL_QIK_SIK1_ST	Q9Y618	NCOR2	P57059	SIK1	T1238	T1241M	1241	Missense	distal	3	no	8.200	8.909	EPSD	COSMIC	6.412	Up-regulation
CAMK_CAMKL_QIK_SIK1_ST	Q9Y618	NCOR2	P57059	SIK1	S1331	A1329V	1329	Missense	proximal	-2	no	6.698	7.067	EPSD	COSMIC	6.412	Up-regulation
CAMK_CAMKL_QIK_SIK1_ST	Q9Y618	NCOR2	P57059	SIK1	T1574	P1567L	1567	Missense	distal	-7	no	7.574	8.029	EPSD	COSMIC;CCLE	6.412	Up-regulation
CAMK_CAMKL_QIK_SIK1_ST	Q9Y618	NCOR2	P57059	SIK1	T1574	P1575T	1575	Missense	proximal	1	no	7.574	7.302	EPSD	COSMIC	6.412	Down-regulation
CAMK_CAMKL_QIK_SIK1_ST	Q9Y618	NCOR2	P57059	SIK1	T1574	P1573Q	1573	Missense	proximal	-1	no	7.574	7.640	EPSD	COSMIC	6.412	Up-regulation
CAMK_CAMKL_QIK_SIK1_ST	Q9Y618	NCOR2	P57059	SIK1	S1584	S1585C	1585	Missense	proximal	1	no	6.464	6.156	EPSD	COSMIC	6.412	Loss
CAMK_CAMKL_QIK_SIK1_ST	Q9Y618	NCOR2	P57059	SIK1	S1584	S1585Y	1585	Missense	proximal	1	no	6.464	5.918	EPSD	COSMIC	6.412	Loss
CAMK_CAMKL_QIK_SIK1_ST	Q9Y618	NCOR2	P57059	SIK1	T1594	P1597H	1597	Missense	distal	3	no	7.007	6.282	EPSD	COSMIC	6.412	Loss
CAMK_CAMKL_QIK_SIK1_ST	Q9Y618	NCOR2	P57059	SIK1	T1594	E1599D	1599	Missense	distal	5	no	7.007	6.877	EPSD	COSMIC	6.412	Down-regulation
CAMK_CAMKL_QIK_SIK1_ST	Q9Y618	NCOR2	P57059	SIK1	S1595	P1597H	1597	Missense	proximal	2	no	8.540	8.562	EPSD	COSMIC	6.412	Up-regulation
CAMK_CAMKL_QIK_SIK1_ST	Q9Y618	NCOR2	P57059	SIK1	S1595	E1599D	1599	Missense	distal	4	no	8.540	8.537	EPSD	COSMIC	6.412	Down-regulation
CAMK_CAMKL_QIK_SIK1_ST	Q9Y618	NCOR2	P57059	SIK1	T1596	P1597H	1597	Missense	proximal	1	no	10.256	10.313	EPSD	COSMIC	6.412	Up-regulation
CAMK_CAMKL_QIK_SIK1_ST	Q9Y618	NCOR2	P57059	SIK1	T1596	E1599D	1599	Missense	distal	3	no	10.256	10.365	EPSD	COSMIC	6.412	Up-regulation
CAMK_CAMKL_QIK_SIK1_ST	Q9Y618	NCOR2	P57059	SIK1	S1606	E1599D	1599	Missense	distal	-7	no	9.032	9.134	EPSD	COSMIC	6.412	Up-regulation
CAMK_CAMKL_QIK_SIK1_ST	Q9Y618	NCOR2	P57059	SIK1	S1726	R1719L	1719	Missense	distal	-7	no	7.332	8.229	EPSD	COSMIC	6.412	Up-regulation
CAMK_CAMKL_QIK_SIK1_ST	Q9Y618	NCOR2	P57059	SIK1	S1726	L1730F	1730	Missense	distal	4	no	7.332	7.215	EPSD	COSMIC	6.412	Down-regulation
CAMK_CAMKL_QIK_SIK1_ST	Q9Y618	NCOR2	P57059	SIK1	S1726	S1726I	1726	Missense	central	0	yes	7.332	0.000	EPSD	COSMIC	6.412	Loss
CAMK_CAMKL_QIK_SIK1_ST	Q9Y618	NCOR2	P57059	SIK1	S1726	S1727F	1727	Missense	proximal	1	no	7.332	6.796	EPSD	COSMIC	6.412	Down-regulation
CAMK_CAMKL_QIK_SIK1_ST	Q9Y618	NCOR2	P57059	SIK1	S1783	P1790L	1790	Missense	distal	7	no	8.658	7.881	EPSD	COSMIC	6.412	Down-regulation
CAMK_CAMKL_QIK_SIK1_ST	Q9Y618	NCOR2	P57059	SIK1	T1798	S1800G	1800	Missense	proximal	2	no	7.353	7.324	EPSD	COSMIC	6.412	Down-regulation
CAMK_CAMKL_QIK_SIK1_ST	Q9Y618	NCOR2	P57059	SIK1	T1798	P1796R	1796	Missense	proximal	-2	no	7.353	8.431	EPSD	COSMIC	6.412	Up-regulation
CAMK_CAMKL_QIK_SIK1_ST	Q9Y618	NCOR2	P57059	SIK1	T1798	T1794M	1794	Missense	distal	-4	no	7.353	6.618	EPSD	COSMIC	6.412	Down-regulation
CAMK_CAMKL_QIK_SIK1_ST	Q9Y618	NCOR2	P57059	SIK1	S1800	P1796R	1796	Missense	distal	-4	no	5.679	9.673	EPSD	COSMIC	6.412	Gain
CAMK_CAMKL_QIK_SIK1_ST	Q9Y618	NCOR2	P57059	SIK1	T1824	R1818S	1818	Missense	distal	-6	no	7.004	6.966	EPSD	COSMIC	6.412	Down-regulation
CAMK_CAMKL_QIK_SIK1_ST	Q9Y618	NCOR2	P57059	SIK1	T1824	T1827N	1827	Missense	distal	3	no	7.004	6.907	EPSD	COSMIC	6.412	Down-regulation
CAMK_CAMKL_QIK_SIK1_ST	Q9Y618	NCOR2	P57059	SIK1	T1828	T1827N	1827	Missense	proximal	-1	no	8.695	8.672	EPSD	COSMIC	6.412	Down-regulation
CAMK_CAMKL_QIK_SIK1_ST	Q9Y618	NCOR2	P57059	SIK1	S2057	S2054N	2054	Missense	distal	-3	no	7.598	8.189	EPSD	COSMIC	6.412	Up-regulation
CAMK_CAMKL_QIK_SIK1_ST	Q9Y618	NCOR2	P57059	SIK1	S2189	L2182F	2182	Missense	distal	-7	no	8.889	8.659	EPSD	COSMIC	6.412	Down-regulation
CAMK_CAMKL_QIK_SIK1_ST	Q9Y618	NCOR2	P57059	SIK1	S2189	P2195L	2195	Missense	distal	6	no	8.889	8.460	EPSD	COSMIC	6.412	Down-regulation
CMGC_MAPK_p38_MAPK14_ST	P49023	PXN	Q16539	MAPK14	T29	P22L	22	Missense	distal	-7	no	12.441	12.248	EPSD	COSMIC	5.915	Down-regulation
CMGC_MAPK_p38_MAPK14_ST	P49023	PXN	Q16539	MAPK14	T29	P22H	22	Missense	distal	-7	no	12.441	12.065	EPSD	COSMIC;GDSC;CCLE	5.915	Down-regulation
CMGC_MAPK_p38_MAPK14_ST	P49023	PXN	Q16539	MAPK14	T29	P30L	30	Missense	proximal	1	no	12.441	4.390	EPSD	COSMIC	5.915	Loss
CMGC_MAPK_p38_MAPK14_ST	P49023	PXN	Q16539	MAPK14	T35	P30L	30	Missense	distal	-5	no	6.288	6.569	EPSD	COSMIC	5.915	Up-regulation
CMGC_MAPK_p38_MAPK14_ST	P49023	PXN	Q16539	MAPK14	S85	S83N	83	Missense	proximal	-2	no	8.951	8.264	PhosphoSitePlus	COSMIC	5.915	Down-regulation
CMGC_MAPK_p38_MAPK14_ST	P49023	PXN	Q16539	MAPK14	S106	P107L	107	Missense	proximal	1	no	10.657	2.606	EPSD	COSMIC;GDSC	5.915	Loss
CMGC_MAPK_p38_MAPK14_ST	P49023	PXN	Q16539	MAPK14	S106	P107Q	107	Missense	proximal	1	no	10.657	3.449	EPSD	COSMIC	5.915	Loss
CMGC_MAPK_p38_MAPK14_ST	P49023	PXN	Q16539	MAPK14	S126	F120S	120	Missense	distal	-6	no	4.594	6.359	EPSD	COSMIC	5.915	Gain
CMGC_MAPK_p38_MAPK14_ST	P49023	PXN	Q16539	MAPK14	S130	V133I	133	Missense	distal	3	no	9.787	9.841	EPSD	COSMIC	5.915	Up-regulation
CMGC_MAPK_p38_MAPK14_ST	P49023	PXN	Q16539	MAPK14	S130	A127T	127	Missense	distal	-3	no	9.787	9.881	EPSD	COSMIC	5.915	Up-regulation
CMGC_MAPK_p38_MAPK14_ST	P49023	PXN	Q16539	MAPK14	S130	T136M	136	Missense	distal	6	no	9.787	9.798	EPSD	COSMIC	5.915	Up-regulation
CMGC_MAPK_p38_MAPK14_ST	P49023	PXN	Q16539	MAPK14	S130	S126P	126	Missense	distal	-4	no	9.787	9.875	EPSD	COSMIC	5.915	Up-regulation
CMGC_MAPK_p38_MAPK14_ST	P49023	PXN	Q16539	MAPK14	S170	D165Y	165	Missense	distal	-5	no	12.253	12.078	EPSD	COSMIC	5.915	Down-regulation
CMGC_MAPK_p38_MAPK14_ST	P49023	PXN	Q16539	MAPK14	S170	G175W	175	Missense	distal	5	no	12.253	11.304	EPSD	COSMIC	5.915	Down-regulation
CMGC_MAPK_p38_MAPK14_ST	P49023	PXN	Q16539	MAPK14	S170	P163L	163	Missense	distal	-7	no	12.253	12.059	EPSD	COSMIC	5.915	Down-regulation
CMGC_MAPK_p38_MAPK14_ST	P49023	PXN	Q16539	MAPK14	S170	P172L	172	Missense	proximal	2	no	12.253	12.140	EPSD	COSMIC	5.915	Down-regulation
CMGC_MAPK_p38_MAPK14_ST	P49023	PXN	Q16539	MAPK14	S170	P171S	171	Missense	proximal	1	no	12.253	4.969	EPSD	COSMIC	5.915	Loss
CMGC_MAPK_p38_MAPK14_ST	P49023	PXN	Q16539	MAPK14	S170	N168I	168	Missense	proximal	-2	no	12.253	12.609	EPSD	COSMIC;GDSC	5.915	Up-regulation
CMGC_MAPK_p38_MAPK14_ST	P49023	PXN	Q16539	MAPK14	S178	G175W	175	Missense	distal	-3	no	11.979	11.073	EPSD	COSMIC	5.915	Down-regulation
CMGC_MAPK_p38_MAPK14_ST	P49023	PXN	Q16539	MAPK14	S178	P172L	172	Missense	distal	-6	no	11.979	11.366	EPSD	COSMIC	5.915	Down-regulation
CMGC_MAPK_p38_MAPK14_ST	P49023	PXN	Q16539	MAPK14	S178	P171S	171	Missense	distal	-7	no	11.979	12.066	EPSD	COSMIC	5.915	Up-regulation
CMGC_MAPK_p38_MAPK14_ST	P49023	PXN	Q16539	MAPK14	S230	P231L	231	Missense	proximal	1	no	10.238	2.187	EPSD	COSMIC;CCLE	5.915	Loss
CMGC_MAPK_p38_MAPK14_ST	P49023	PXN	Q16539	MAPK14	S230	P229L	229	Missense	proximal	-1	no	10.238	10.424	EPSD	COSMIC	5.915	Up-regulation
CMGC_MAPK_p38_MAPK14_ST	P49023	PXN	Q16539	MAPK14	S244	E241D	241	Missense	distal	-3	no	9.196	8.990	EPSD	COSMIC	5.915	Down-regulation
CMGC_MAPK_p38_MAPK14_ST	P49023	PXN	Q16539	MAPK14	S261	R256H	256	Missense	distal	-5	no	5.854	6.398	EPSD	COSMIC	5.915	Gain
CMGC_MAPK_p38_MAPK14_ST	P49023	PXN	Q16539	MAPK14	S303	P304L	304	Missense	proximal	1	no	9.882	1.832	EPSD	COSMIC	5.915	Loss
CMGC_MAPK_p38_MAPK14_ST	P49023	PXN	Q16539	MAPK14	S303	P304R	304	Missense	proximal	1	no	9.882	1.947	EPSD	COSMIC	5.915	Loss
CMGC_MAPK_p38_MAPK14_ST	P49023	PXN	Q16539	MAPK14	S303	G300R	300	Missense	distal	-3	no	9.882	11.333	EPSD	COSMIC	5.915	Up-regulation
CMGC_MAPK_p38_MAPK14_ST	P49023	PXN	Q16539	MAPK14	S303	E309K	309	Missense	distal	6	no	9.882	9.877	EPSD	COSMIC	5.915	Down-regulation
CMGC_MAPK_p38_MAPK14_ST	P49023	PXN	Q16539	MAPK14	S303	D298Y	298	Missense	distal	-5	no	9.882	9.707	EPSD	COSMIC	5.915	Down-regulation
CMGC_MAPK_p38_MAPK14_ST	P49023	PXN	Q16539	MAPK14	S303	S303R	303	Missense	central	0	yes	9.882	0.000	EPSD	COSMIC	5.915	Loss
CMGC_MAPK_p38_MAPK14_ST	P49023	PXN	Q16539	MAPK14	S303	G306R	306	Missense	distal	3	no	9.882	9.868	EPSD	COSMIC	5.915	Down-regulation
CMGC_MAPK_p38_MAPK14_ST	P49023	PXN	Q16539	MAPK14	S303	R301Q	301	Missense	proximal	-2	no	9.882	9.556	EPSD	COSMIC	5.915	Down-regulation
CMGC_MAPK_p38_MAPK14_ST	P49023	PXN	Q16539	MAPK14	S303	G299S	299	Missense	distal	-4	no	9.882	9.884	EPSD	COSMIC	5.915	Up-regulation
CMGC_MAPK_p38_MAPK14_ST	P49023	PXN	Q16539	MAPK14	S322	P328S	328	Missense	distal	6	no	10.603	10.591	EPSD	COSMIC	5.915	Down-regulation
CMGC_MAPK_p38_MAPK14_ST	P49023	PXN	Q16539	MAPK14	S322	S322A	322	Missense	central	0	yes	10.603	0.000	EPSD	COSMIC	5.915	Loss
CMGC_MAPK_p38_MAPK14_ST	P49023	PXN	Q16539	MAPK14	S414	K407E	407	Missense	distal	-7	no	9.224	9.278	EPSD	COSMIC	5.915	Up-regulation
CMGC_MAPK_p38_MAPK14_ST	P49023	PXN	Q16539	MAPK14	S414	R416H	416	Missense	proximal	2	no	9.224	8.842	EPSD	COSMIC	5.915	Down-regulation
CMGC_MAPK_p38_MAPK14_ST	P49023	PXN	Q16539	MAPK14	S414	F413L	413	Missense	proximal	-1	no	9.224	9.260	EPSD	COSMIC	5.915	Up-regulation
CMGC_MAPK_p38_MAPK14_ST	Q13155	AIMP2	Q16539	MAPK14	S130	P128S	128	Missense	proximal	-2	no	11.674	11.186	EPSD	COSMIC	5.915	Down-regulation
CMGC_MAPK_p38_MAPK14_ST	Q13155	AIMP2	Q16539	MAPK14	S130	P128T	128	Missense	proximal	-2	no	11.674	10.955	EPSD	COSMIC	5.915	Down-regulation
CMGC_MAPK_p38_MAPK14_ST	Q13155	AIMP2	Q16539	MAPK14	S156	V158G	158	Missense	proximal	2	no	8.414	8.613	PhosphoSitePlus	COSMIC	5.915	Up-regulation
CMGC_MAPK_p38_MAPK14_ST	Q13155	AIMP2	Q16539	MAPK14	S156	T154M	154	Missense	proximal	-2	no	8.414	8.322	PhosphoSitePlus	COSMIC	5.915	Down-regulation
CMGC_MAPK_p38_MAPK14_ST	Q02078	MEF2A	Q16539	MAPK14	S98	T103M	103	Missense	distal	5	no	10.930	10.617	EPSD;PhosphoSitePlus	COSMIC	5.915	Down-regulation
CMGC_MAPK_p38_MAPK14_ST	Q02078	MEF2A	Q16539	MAPK14	S98	R94G	94	Missense	distal	-4	no	10.930	10.916	EPSD;PhosphoSitePlus	COSMIC;GDSC;CCLE	5.915	Down-regulation
CMGC_MAPK_p38_MAPK14_ST	Q02078	MEF2A	Q16539	MAPK14	S98	G95A	95	Missense	distal	-3	no	10.930	11.455	EPSD;PhosphoSitePlus	COSMIC	5.915	Up-regulation
CMGC_MAPK_p38_MAPK14_ST	Q02078	MEF2A	Q16539	MAPK14	T108	T103M	103	Missense	distal	-5	no	12.793	12.505	EPSD;PhosphoSitePlus	COSMIC	5.915	Down-regulation
CMGC_MAPK_p38_MAPK14_ST	Q02078	MEF2A	Q16539	MAPK14	S181	S178N	178	Missense	distal	-3	no	13.783	12.636	EPSD	COSMIC	5.915	Down-regulation
CMGC_MAPK_p38_MAPK14_ST	Q02078	MEF2A	Q16539	MAPK14	S181	S178R	178	Missense	distal	-3	no	13.783	14.296	EPSD	COSMIC	5.915	Up-regulation
CMGC_MAPK_p38_MAPK14_ST	Q02078	MEF2A	Q16539	MAPK14	S192	G194R	194	Missense	proximal	2	no	11.537	11.621	PhosphoSitePlus;EPSD	COSMIC	5.915	Up-regulation
CMGC_MAPK_p38_MAPK14_ST	Q02078	MEF2A	Q16539	MAPK14	S192	Q197E	197	Missense	distal	5	no	11.537	12.159	PhosphoSitePlus;EPSD	COSMIC	5.915	Up-regulation
CMGC_MAPK_p38_MAPK14_ST	Q02078	MEF2A	Q16539	MAPK14	S201	G194R	194	Missense	distal	-7	no	7.387	7.285	EPSD	COSMIC	5.915	Down-regulation
CMGC_MAPK_p38_MAPK14_ST	Q02078	MEF2A	Q16539	MAPK14	S201	Q197E	197	Missense	distal	-4	no	7.387	6.709	EPSD	COSMIC	5.915	Down-regulation
CMGC_MAPK_p38_MAPK14_ST	Q02078	MEF2A	Q16539	MAPK14	S223	P224A	224	Missense	proximal	1	no	11.196	4.877	EPSD;PhosphoSitePlus	COSMIC	5.915	Loss
CMGC_MAPK_p38_MAPK14_ST	Q02078	MEF2A	Q16539	MAPK14	S223	G221E	221	Missense	proximal	-2	no	11.196	11.874	EPSD;PhosphoSitePlus	COSMIC	5.915	Up-regulation
CMGC_MAPK_p38_MAPK14_ST	Q02078	MEF2A	Q16539	MAPK14	S223	G219E	219	Missense	distal	-4	no	11.196	10.899	EPSD;PhosphoSitePlus	COSMIC	5.915	Down-regulation
CMGC_MAPK_p38_MAPK14_ST	Q02078	MEF2A	Q16539	MAPK14	S235	P236L	236	Missense	proximal	1	no	11.534	3.483	EPSD	COSMIC	5.915	Loss
CMGC_MAPK_p38_MAPK14_ST	Q02078	MEF2A	Q16539	MAPK14	S235	T242A	242	Missense	distal	7	no	11.534	11.877	EPSD	COSMIC	5.915	Up-regulation
CMGC_MAPK_p38_MAPK14_ST	Q02078	MEF2A	Q16539	MAPK14	S255	P256A	256	Missense	proximal	1	no	10.492	4.174	EPSD	COSMIC	5.915	Loss
CMGC_MAPK_p38_MAPK14_ST	Q02078	MEF2A	Q16539	MAPK14	T319	P323L	323	Missense	distal	4	no	9.815	9.176	EPSD;PhosphoSitePlus	COSMIC	5.915	Down-regulation
CMGC_MAPK_p38_MAPK14_ST	Q02078	MEF2A	Q16539	MAPK14	S355	Q351P	351	Missense	distal	-4	no	10.244	9.953	EPSD	COSMIC	5.915	Down-regulation
CMGC_MAPK_p38_MAPK14_ST	Q02078	MEF2A	Q16539	MAPK14	S355	Q351H	351	Missense	distal	-4	no	10.244	10.087	EPSD	COSMIC	5.915	Down-regulation
CMGC_MAPK_p38_MAPK14_ST	Q02078	MEF2A	Q16539	MAPK14	T415	Q420P	420	Missense	distal	5	no	7.415	7.624	EPSD	COSMIC	5.915	Up-regulation
CMGC_MAPK_p38_MAPK14_ST	Q02078	MEF2A	Q16539	MAPK14	S453	S453R	453	Missense	central	0	yes	8.930	0.000	EPSD	COSMIC	5.915	Loss
CMGC_MAPK_p38_MAPK14_ST	Q02078	MEF2A	Q16539	MAPK14	S463	S461R	461	Missense	proximal	-2	no	6.398	6.198	EPSD	COSMIC	5.915	Down-regulation
CMGC_MAPK_p38_MAPK14_ST	P04150	NR3C1	Q16539	MAPK14	T8	R11I	11	Missense	distal	3	no	12.176	12.244	EPSD	COSMIC;GDSC;CCLE	5.915	Up-regulation
CMGC_MAPK_p38_MAPK14_ST	P04150	NR3C1	Q16539	MAPK14	T8	P15L	15	Missense	distal	7	no	12.176	12.013	EPSD	COSMIC	5.915	Down-regulation
CMGC_MAPK_p38_MAPK14_ST	P04150	NR3C1	Q16539	MAPK14	S45	A49V	49	Missense	distal	4	no	10.868	10.434	EPSD	COSMIC	5.915	Down-regulation
CMGC_MAPK_p38_MAPK14_ST	P04150	NR3C1	Q16539	MAPK14	S47	A49V	49	Missense	proximal	2	no	7.746	7.583	EPSD	COSMIC	5.915	Down-regulation
CMGC_MAPK_p38_MAPK14_ST	P04150	NR3C1	Q16539	MAPK14	T133	E137D	137	Missense	distal	4	no	6.481	4.811	EPSD	COSMIC	5.915	Loss
CMGC_MAPK_p38_MAPK14_ST	P04150	NR3C1	Q16539	MAPK14	T133	S132L	132	Missense	proximal	-1	no	6.481	6.759	EPSD	COSMIC	5.915	Up-regulation
CMGC_MAPK_p38_MAPK14_ST	P04150	NR3C1	Q16539	MAPK14	S144	E137D	137	Missense	distal	-7	no	6.120	5.539	EPSD	COSMIC	5.915	Loss
CMGC_MAPK_p38_MAPK14_ST	P04150	NR3C1	Q16539	MAPK14	S144	A146V	146	Missense	proximal	2	no	6.120	5.956	EPSD	COSMIC;GDSC;CCLE	5.915	Down-regulation
CMGC_MAPK_p38_MAPK14_ST	P04150	NR3C1	Q16539	MAPK14	S144	A146S	146	Missense	proximal	2	no	6.120	6.384	EPSD	COSMIC;GDSC;CCLE	5.915	Up-regulation
CMGC_MAPK_p38_MAPK14_ST	P04150	NR3C1	Q16539	MAPK14	S144	S142L	142	Missense	proximal	-2	no	6.120	5.229	EPSD	COSMIC	5.915	Loss
CMGC_MAPK_p38_MAPK14_ST	P04150	NR3C1	Q16539	MAPK14	S144	A150S	150	Missense	distal	6	no	6.120	6.065	EPSD	COSMIC	5.915	Down-regulation
CMGC_MAPK_p38_MAPK14_ST	P04150	NR3C1	Q16539	MAPK14	S148	A146V	146	Missense	proximal	-2	no	6.149	5.734	EPSD	COSMIC;GDSC;CCLE	5.915	Loss
CMGC_MAPK_p38_MAPK14_ST	P04150	NR3C1	Q16539	MAPK14	S148	A146S	146	Missense	proximal	-2	no	6.149	6.323	EPSD	COSMIC;GDSC;CCLE	5.915	Up-regulation
CMGC_MAPK_p38_MAPK14_ST	P04150	NR3C1	Q16539	MAPK14	S148	S142L	142	Missense	distal	-6	no	6.149	4.929	EPSD	COSMIC	5.915	Loss
CMGC_MAPK_p38_MAPK14_ST	P04150	NR3C1	Q16539	MAPK14	S148	A150S	150	Missense	proximal	2	no	6.149	6.413	EPSD	COSMIC	5.915	Up-regulation
CMGC_MAPK_p38_MAPK14_ST	P04150	NR3C1	Q16539	MAPK14	S148	E155G	155	Missense	distal	7	no	6.149	5.788	EPSD	COSMIC	5.915	Loss
CMGC_MAPK_p38_MAPK14_ST	P04150	NR3C1	Q16539	MAPK14	S203	T208A	208	Missense	distal	5	no	12.057	11.585	PhosphoSitePlus;EPSD	COSMIC	5.915	Down-regulation
CMGC_MAPK_p38_MAPK14_ST	P04150	NR3C1	Q16539	MAPK14	S211	T208A	208	Missense	distal	-3	no	10.702	10.607	EPSD;PhosphoSitePlus	COSMIC	5.915	Down-regulation
CMGC_MAPK_p38_MAPK14_ST	P04150	NR3C1	Q16539	MAPK14	S267	P268L	268	Missense	proximal	1	no	10.514	2.464	EPSD	COSMIC	5.915	Loss
CMGC_MAPK_p38_MAPK14_ST	P04150	NR3C1	Q16539	MAPK14	T288	E285K	285	Missense	distal	-3	no	11.174	10.782	EPSD	COSMIC	5.915	Down-regulation
CMGC_MAPK_p38_MAPK14_ST	P04150	NR3C1	Q16539	MAPK14	S395	Y393H	393	Missense	proximal	-2	no	9.357	7.577	EPSD	COSMIC	5.915	Down-regulation
CMGC_MAPK_p38_MAPK14_ST	P04150	NR3C1	Q16539	MAPK14	S404	P405T	405	Missense	proximal	1	no	10.424	2.970	EPSD	COSMIC	5.915	Loss
CMGC_MAPK_p38_MAPK14_ST	P04150	NR3C1	Q16539	MAPK14	S410	G415V	415	Missense	distal	5	no	7.787	7.385	EPSD	COSMIC	5.915	Down-regulation
CMGC_MAPK_p38_MAPK14_ST	P04150	NR3C1	Q16539	MAPK14	S410	P405T	405	Missense	distal	-5	no	7.787	7.780	EPSD	COSMIC	5.915	Down-regulation
CMGC_MAPK_p38_MAPK14_ST	P19634	SLC9A1	Q16539	MAPK14	S11	R4W	4	Missense	distal	-7	no	9.503	8.763	EPSD	COSMIC	5.915	Down-regulation
CMGC_MAPK_p38_MAPK14_ST	P19634	SLC9A1	Q16539	MAPK14	T68	T68I	68	Missense	central	0	yes	12.510	0.000	EPSD	COSMIC	5.915	Loss
CMGC_MAPK_p38_MAPK14_ST	P19634	SLC9A1	Q16539	MAPK14	T68	V67I	67	Missense	proximal	-1	no	12.510	12.272	EPSD	COSMIC	5.915	Down-regulation
CMGC_MAPK_p38_MAPK14_ST	P19634	SLC9A1	Q16539	MAPK14	S693	R700H	700	Missense	distal	7	no	10.047	9.513	EPSD	COSMIC;GDSC;CCLE	5.915	Down-regulation
CMGC_MAPK_p38_MAPK14_ST	P19634	SLC9A1	Q16539	MAPK14	S703	R700H	700	Missense	distal	-3	no	6.509	4.755	EPSD	COSMIC;GDSC;CCLE	5.915	Loss
CMGC_MAPK_p38_MAPK14_ST	P19634	SLC9A1	Q16539	MAPK14	T718	P715S	715	Missense	distal	-3	no	5.606	6.370	EPSD;PhosphoSitePlus	COSMIC	5.915	Gain
CMGC_MAPK_p38_MAPK14_ST	P19634	SLC9A1	Q16539	MAPK14	S723	P724Q	724	Missense	proximal	1	no	11.402	4.194	EPSD;PhosphoSitePlus	COSMIC	5.915	Loss
CMGC_MAPK_p38_MAPK14_ST	P19634	SLC9A1	Q16539	MAPK14	S723	I717V	717	Missense	distal	-6	no	11.402	11.667	EPSD;PhosphoSitePlus	COSMIC	5.915	Up-regulation
CMGC_MAPK_p38_MAPK14_ST	P19634	SLC9A1	Q16539	MAPK14	S726	P724Q	724	Missense	proximal	-2	no	10.305	9.290	PhosphoSitePlus;EPSD	COSMIC	5.915	Down-regulation
CMGC_MAPK_p38_MAPK14_ST	P19634	SLC9A1	Q16539	MAPK14	S729	P724Q	724	Missense	distal	-5	no	6.960	6.688	EPSD;PhosphoSitePlus	COSMIC	5.915	Down-regulation
CMGC_MAPK_p38_MAPK14_ST	P19634	SLC9A1	Q16539	MAPK14	S770	P772S	772	Missense	proximal	2	no	5.683	6.060	EPSD	COSMIC	5.915	Gain
CMGC_MAPK_p38_MAPK14_ST	P19634	SLC9A1	Q16539	MAPK14	S771	P772L	772	Missense	proximal	1	no	6.985	-1.066	EPSD	COSMIC	5.915	Loss
CMGC_MAPK_p38_MAPK14_ST	P19634	SLC9A1	Q16539	MAPK14	S771	P772S	772	Missense	proximal	1	no	6.985	-0.299	EPSD	COSMIC	5.915	Loss
CMGC_MAPK_p38_MAPK14_ST	P19634	SLC9A1	Q16539	MAPK14	T779	P780S	780	Missense	proximal	1	no	11.034	3.750	EPSD	COSMIC	5.915	Loss
CMGC_MAPK_p38_MAPK14_ST	P19634	SLC9A1	Q16539	MAPK14	T779	P772L	772	Missense	distal	-7	no	11.034	10.840	EPSD	COSMIC	5.915	Down-regulation
CMGC_MAPK_p38_MAPK14_ST	P19634	SLC9A1	Q16539	MAPK14	T779	P786S	786	Missense	distal	7	no	11.034	11.255	EPSD	COSMIC	5.915	Up-regulation
CMGC_MAPK_p38_MAPK14_ST	P19634	SLC9A1	Q16539	MAPK14	T779	P772S	772	Missense	distal	-7	no	11.034	11.121	EPSD	COSMIC	5.915	Up-regulation
CMGC_MAPK_p38_MAPK14_ST	P19634	SLC9A1	Q16539	MAPK14	S785	P780S	780	Missense	distal	-5	no	10.117	9.669	EPSD	COSMIC	5.915	Down-regulation
CMGC_MAPK_p38_MAPK14_ST	P19634	SLC9A1	Q16539	MAPK14	S785	P786S	786	Missense	proximal	1	no	10.117	2.833	EPSD	COSMIC	5.915	Loss
CMGC_MAPK_p38_MAPK14_ST	Q09472	EP300	Q16539	MAPK14	S20	A13T	13	Missense	distal	-7	no	10.459	10.276	EPSD	COSMIC	5.915	Down-regulation
CMGC_MAPK_p38_MAPK14_ST	Q09472	EP300	Q16539	MAPK14	S20	P21L	21	Missense	proximal	1	no	10.459	2.408	EPSD	COSMIC	5.915	Loss
CMGC_MAPK_p38_MAPK14_ST	Q09472	EP300	Q16539	MAPK14	S20	A13V	13	Missense	distal	-7	no	10.459	9.640	EPSD	COSMIC	5.915	Down-regulation
CMGC_MAPK_p38_MAPK14_ST	Q09472	EP300	Q16539	MAPK14	S24	G30V	30	Missense	distal	6	no	6.820	6.458	EPSD	COSMIC;CCLE	5.915	Down-regulation
CMGC_MAPK_p38_MAPK14_ST	Q09472	EP300	Q16539	MAPK14	S24	G30D	30	Missense	distal	6	no	6.820	6.678	EPSD	COSMIC	5.915	Down-regulation
CMGC_MAPK_p38_MAPK14_ST	Q09472	EP300	Q16539	MAPK14	S24	P21L	21	Missense	distal	-3	no	6.820	5.853	EPSD	COSMIC	5.915	Loss
CMGC_MAPK_p38_MAPK14_ST	Q09472	EP300	Q16539	MAPK14	S89	M95V	95	Missense	distal	6	no	8.000	7.710	EPSD	COSMIC	5.915	Down-regulation
CMGC_MAPK_p38_MAPK14_ST	Q09472	EP300	Q16539	MAPK14	S89	S87Y	87	Missense	proximal	-2	no	8.000	8.002	EPSD	COSMIC	5.915	Up-regulation
CMGC_MAPK_p38_MAPK14_ST	Q09472	EP300	Q16539	MAPK14	S90	M95V	95	Missense	distal	5	no	10.176	9.998	EPSD	COSMIC	5.915	Down-regulation
CMGC_MAPK_p38_MAPK14_ST	Q09472	EP300	Q16539	MAPK14	S90	S87Y	87	Missense	distal	-3	no	10.176	9.282	EPSD	COSMIC	5.915	Down-regulation
CMGC_MAPK_p38_MAPK14_ST	Q09472	EP300	Q16539	MAPK14	S112	S112N	112	Missense	central	0	yes	9.094	0.000	EPSD	COSMIC	5.915	Loss
CMGC_MAPK_p38_MAPK14_ST	Q09472	EP300	Q16539	MAPK14	S112	A108V	108	Missense	distal	-4	no	9.094	9.377	EPSD	COSMIC	5.915	Up-regulation
CMGC_MAPK_p38_MAPK14_ST	Q09472	EP300	Q16539	MAPK14	S112	Q107H	107	Missense	distal	-5	no	9.094	9.680	EPSD	COSMIC	5.915	Up-regulation
CMGC_MAPK_p38_MAPK14_ST	Q09472	EP300	Q16539	MAPK14	S227	E221G	221	Missense	distal	-6	no	9.886	9.576	EPSD	COSMIC	5.915	Down-regulation
CMGC_MAPK_p38_MAPK14_ST	Q09472	EP300	Q16539	MAPK14	S227	G231E	231	Missense	distal	4	no	9.886	10.618	EPSD	COSMIC	5.915	Up-regulation
CMGC_MAPK_p38_MAPK14_ST	Q09472	EP300	Q16539	MAPK14	S255	P252L	252	Missense	distal	-3	no	12.033	11.065	EPSD	COSMIC	5.915	Down-regulation
CMGC_MAPK_p38_MAPK14_ST	Q09472	EP300	Q16539	MAPK14	S255	Y253C	253	Missense	proximal	-2	no	12.033	10.895	EPSD	COSMIC	5.915	Down-regulation
CMGC_MAPK_p38_MAPK14_ST	Q09472	EP300	Q16539	MAPK14	S255	N248T	248	Missense	distal	-7	no	12.033	12.174	EPSD	COSMIC	5.915	Up-regulation
CMGC_MAPK_p38_MAPK14_ST	Q09472	EP300	Q16539	MAPK14	S255	P250H	250	Missense	distal	-5	no	12.033	12.346	EPSD	COSMIC	5.915	Up-regulation
CMGC_MAPK_p38_MAPK14_ST	Q09472	EP300	Q16539	MAPK14	S255	P252S	252	Missense	distal	-3	no	12.033	12.796	EPSD	COSMIC	5.915	Up-regulation
CMGC_MAPK_p38_MAPK14_ST	Q09472	EP300	Q16539	MAPK14	S255	S255L	255	Missense	central	0	yes	12.033	0.000	EPSD	COSMIC	5.915	Loss
CMGC_MAPK_p38_MAPK14_ST	Q09472	EP300	Q16539	MAPK14	S255	P256S	256	Missense	proximal	1	no	12.033	4.749	EPSD	COSMIC	5.915	Loss
CMGC_MAPK_p38_MAPK14_ST	Q09472	EP300	Q16539	MAPK14	S255	P250S	250	Missense	distal	-5	no	12.033	11.585	EPSD	COSMIC	5.915	Down-regulation
CMGC_MAPK_p38_MAPK14_ST	Q09472	EP300	Q16539	MAPK14	S255	N248H	248	Missense	distal	-7	no	12.033	11.780	EPSD	COSMIC	5.915	Down-regulation
CMGC_MAPK_p38_MAPK14_ST	Q09472	EP300	Q16539	MAPK14	S285	D290N	290	Missense	distal	5	no	11.201	11.410	EPSD	COSMIC	5.915	Up-regulation
CMGC_MAPK_p38_MAPK14_ST	Q09472	EP300	Q16539	MAPK14	S285	V279A	279	Missense	distal	-6	no	11.201	11.689	EPSD	COSMIC	5.915	Up-regulation
CMGC_MAPK_p38_MAPK14_ST	Q09472	EP300	Q16539	MAPK14	T317	G314V	314	Missense	distal	-3	no	9.145	8.170	EPSD	COSMIC	5.915	Down-regulation
CMGC_MAPK_p38_MAPK14_ST	Q09472	EP300	Q16539	MAPK14	T317	P313S	313	Missense	distal	-4	no	9.145	9.057	EPSD	COSMIC	5.915	Down-regulation
CMGC_MAPK_p38_MAPK14_ST	Q09472	EP300	Q16539	MAPK14	S396	R397P	397	Missense	proximal	1	no	2.330	10.265	EPSD	COSMIC	5.915	Gain
CMGC_MAPK_p38_MAPK14_ST	Q09472	EP300	Q16539	MAPK14	S499	P500S	500	Missense	proximal	1	no	10.750	3.466	EPSD	COSMIC	5.915	Loss
CMGC_MAPK_p38_MAPK14_ST	Q09472	EP300	Q16539	MAPK14	S499	R504W	504	Missense	distal	5	no	10.750	9.856	EPSD	COSMIC	5.915	Down-regulation
CMGC_MAPK_p38_MAPK14_ST	Q09472	EP300	Q16539	MAPK14	S831	L827P	827	Missense	distal	-4	no	9.403	8.891	EPSD	COSMIC	5.915	Down-regulation
CMGC_MAPK_p38_MAPK14_ST	Q09472	EP300	Q16539	MAPK14	S831	R838S	838	Missense	distal	7	no	9.403	9.369	EPSD	COSMIC	5.915	Down-regulation
CMGC_MAPK_p38_MAPK14_ST	Q09472	EP300	Q16539	MAPK14	S833	T839I	839	Missense	distal	6	no	12.412	12.164	EPSD	COSMIC	5.915	Down-regulation
CMGC_MAPK_p38_MAPK14_ST	Q09472	EP300	Q16539	MAPK14	S833	L827P	827	Missense	distal	-6	no	12.412	13.026	EPSD	COSMIC	5.915	Up-regulation
CMGC_MAPK_p38_MAPK14_ST	Q09472	EP300	Q16539	MAPK14	S833	R838S	838	Missense	distal	5	no	12.412	12.723	EPSD	COSMIC	5.915	Up-regulation
CMGC_MAPK_p38_MAPK14_ST	Q09472	EP300	Q16539	MAPK14	T839	T845S	845	Missense	distal	6	no	9.838	9.801	EPSD	COSMIC	5.915	Down-regulation
CMGC_MAPK_p38_MAPK14_ST	Q09472	EP300	Q16539	MAPK14	T839	P842S	842	Missense	distal	3	no	9.838	9.798	EPSD	COSMIC;CCLE	5.915	Down-regulation
CMGC_MAPK_p38_MAPK14_ST	Q09472	EP300	Q16539	MAPK14	T839	T839I	839	Missense	central	0	yes	9.838	0.000	EPSD	COSMIC	5.915	Loss
CMGC_MAPK_p38_MAPK14_ST	Q09472	EP300	Q16539	MAPK14	T839	P846S	846	Missense	distal	7	no	9.838	10.060	EPSD	COSMIC	5.915	Up-regulation
CMGC_MAPK_p38_MAPK14_ST	Q09472	EP300	Q16539	MAPK14	T839	P842L	842	Missense	distal	3	no	9.838	9.872	EPSD	COSMIC	5.915	Up-regulation
CMGC_MAPK_p38_MAPK14_ST	Q09472	EP300	Q16539	MAPK14	T839	R838S	838	Missense	proximal	-1	no	9.838	9.946	EPSD	COSMIC	5.915	Up-regulation
CMGC_MAPK_p38_MAPK14_ST	Q09472	EP300	Q16539	MAPK14	T841	T845S	845	Missense	distal	4	no	11.347	11.608	EPSD	COSMIC	5.915	Up-regulation
CMGC_MAPK_p38_MAPK14_ST	Q09472	EP300	Q16539	MAPK14	T841	P842S	842	Missense	proximal	1	no	11.347	4.063	EPSD	COSMIC;CCLE	5.915	Loss
CMGC_MAPK_p38_MAPK14_ST	Q09472	EP300	Q16539	MAPK14	T841	T839I	839	Missense	proximal	-2	no	11.347	11.249	EPSD	COSMIC	5.915	Down-regulation
CMGC_MAPK_p38_MAPK14_ST	Q09472	EP300	Q16539	MAPK14	T841	P846S	846	Missense	distal	5	no	11.347	11.798	EPSD	COSMIC	5.915	Up-regulation
CMGC_MAPK_p38_MAPK14_ST	Q09472	EP300	Q16539	MAPK14	T841	P847S	847	Missense	distal	6	no	11.347	11.335	EPSD	COSMIC	5.915	Down-regulation
CMGC_MAPK_p38_MAPK14_ST	Q09472	EP300	Q16539	MAPK14	T841	P842L	842	Missense	proximal	1	no	11.347	3.296	EPSD	COSMIC	5.915	Loss
CMGC_MAPK_p38_MAPK14_ST	Q09472	EP300	Q16539	MAPK14	T841	R838S	838	Missense	distal	-3	no	11.347	10.835	EPSD	COSMIC	5.915	Down-regulation
CMGC_MAPK_p38_MAPK14_ST	Q09472	EP300	Q16539	MAPK14	T845	P842S	842	Missense	distal	-3	no	7.713	8.477	EPSD	COSMIC;CCLE	5.915	Up-regulation
CMGC_MAPK_p38_MAPK14_ST	Q09472	EP300	Q16539	MAPK14	T845	T839I	839	Missense	distal	-6	no	7.713	6.690	EPSD	COSMIC	5.915	Down-regulation
CMGC_MAPK_p38_MAPK14_ST	Q09472	EP300	Q16539	MAPK14	T845	P846S	846	Missense	proximal	1	no	7.713	0.429	EPSD	COSMIC	5.915	Loss
CMGC_MAPK_p38_MAPK14_ST	Q09472	EP300	Q16539	MAPK14	T845	P847S	847	Missense	proximal	2	no	7.713	8.090	EPSD	COSMIC	5.915	Up-regulation
CMGC_MAPK_p38_MAPK14_ST	Q09472	EP300	Q16539	MAPK14	T845	I849T	849	Missense	distal	4	no	7.713	8.240	EPSD	COSMIC	5.915	Up-regulation
CMGC_MAPK_p38_MAPK14_ST	Q09472	EP300	Q16539	MAPK14	T845	P842L	842	Missense	distal	-3	no	7.713	6.745	EPSD	COSMIC	5.915	Down-regulation
CMGC_MAPK_p38_MAPK14_ST	Q09472	EP300	Q16539	MAPK14	T845	R838S	838	Missense	distal	-7	no	7.713	7.882	EPSD	COSMIC	5.915	Up-regulation
CMGC_MAPK_p38_MAPK14_ST	Q09472	EP300	Q16539	MAPK14	T865	A868V	868	Missense	distal	3	no	10.860	10.888	EPSD	COSMIC	5.915	Up-regulation
CMGC_MAPK_p38_MAPK14_ST	Q09472	EP300	Q16539	MAPK14	T865	I859S	859	Missense	distal	-6	no	10.860	12.155	EPSD	COSMIC	5.915	Up-regulation
CMGC_MAPK_p38_MAPK14_ST	Q09472	EP300	Q16539	MAPK14	T865	P870S	870	Missense	distal	5	no	10.860	11.311	EPSD	COSMIC	5.915	Up-regulation
CMGC_MAPK_p38_MAPK14_ST	Q09472	EP300	Q16539	MAPK14	T865	P864S	864	Missense	proximal	-1	no	10.860	10.768	EPSD	COSMIC	5.915	Down-regulation
CMGC_MAPK_p38_MAPK14_ST	Q09472	EP300	Q16539	MAPK14	T885	T890P	890	Missense	distal	5	no	9.555	9.271	EPSD	COSMIC	5.915	Down-regulation
CMGC_MAPK_p38_MAPK14_ST	Q09472	EP300	Q16539	MAPK14	T885	P882R	882	Missense	distal	-3	no	9.555	10.832	EPSD	COSMIC	5.915	Up-regulation
CMGC_MAPK_p38_MAPK14_ST	Q09472	EP300	Q16539	MAPK14	T885	T891P	891	Missense	distal	6	no	9.555	9.530	EPSD	COSMIC;CCLE	5.915	Down-regulation
CMGC_MAPK_p38_MAPK14_ST	Q09472	EP300	Q16539	MAPK14	T885	P882S	882	Missense	distal	-3	no	9.555	10.319	EPSD	COSMIC	5.915	Up-regulation
CMGC_MAPK_p38_MAPK14_ST	Q09472	EP300	Q16539	MAPK14	T887	T890P	890	Missense	distal	3	no	9.099	9.126	EPSD	COSMIC	5.915	Up-regulation
CMGC_MAPK_p38_MAPK14_ST	Q09472	EP300	Q16539	MAPK14	T887	P882R	882	Missense	distal	-5	no	9.099	8.870	EPSD	COSMIC	5.915	Down-regulation
CMGC_MAPK_p38_MAPK14_ST	Q09472	EP300	Q16539	MAPK14	T887	P894S	894	Missense	distal	7	no	9.099	9.321	EPSD	COSMIC	5.915	Up-regulation
CMGC_MAPK_p38_MAPK14_ST	Q09472	EP300	Q16539	MAPK14	T887	T891P	891	Missense	distal	4	no	9.099	8.921	EPSD	COSMIC;CCLE	5.915	Down-regulation
CMGC_MAPK_p38_MAPK14_ST	Q09472	EP300	Q16539	MAPK14	T887	P882S	882	Missense	distal	-5	no	9.099	8.652	EPSD	COSMIC	5.915	Down-regulation
CMGC_MAPK_p38_MAPK14_ST	Q09472	EP300	Q16539	MAPK14	T890	T891P	891	Missense	proximal	1	no	2.606	10.059	EPSD	COSMIC;CCLE	5.915	Gain
CMGC_MAPK_p38_MAPK14_ST	Q09472	EP300	Q16539	MAPK14	S906	A903S	903	Missense	distal	-3	no	5.524	5.936	EPSD	COSMIC	5.915	Gain
CMGC_MAPK_p38_MAPK14_ST	Q09472	EP300	Q16539	MAPK14	T938	P933S	933	Missense	distal	-5	no	7.571	7.123	EPSD	COSMIC	5.915	Down-regulation
CMGC_MAPK_p38_MAPK14_ST	Q09472	EP300	Q16539	MAPK14	S1009	T1010A	1010	Missense	proximal	1	no	5.031	6.166	EPSD	COSMIC	5.915	Gain
CMGC_MAPK_p38_MAPK14_ST	Q09472	EP300	Q16539	MAPK14	S1016	I1023V	1023	Missense	distal	7	no	5.774	6.420	EPSD	COSMIC	5.915	Gain
CMGC_MAPK_p38_MAPK14_ST	Q09472	EP300	Q16539	MAPK14	S1016	E1011K	1011	Missense	distal	-5	no	5.774	6.108	EPSD	COSMIC	5.915	Gain
CMGC_MAPK_p38_MAPK14_ST	Q09472	EP300	Q16539	MAPK14	S1033	S1037L	1037	Missense	distal	4	no	7.714	6.636	EPSD	COSMIC	5.915	Down-regulation
CMGC_MAPK_p38_MAPK14_ST	Q09472	EP300	Q16539	MAPK14	S1033	D1028N	1028	Missense	distal	-5	no	7.714	7.555	EPSD	COSMIC	5.915	Down-regulation
CMGC_MAPK_p38_MAPK14_ST	Q09472	EP300	Q16539	MAPK14	S1038	S1037L	1037	Missense	proximal	-1	no	10.963	11.241	EPSD	COSMIC	5.915	Up-regulation
CMGC_MAPK_p38_MAPK14_ST	Q09472	EP300	Q16539	MAPK14	S1038	G1042R	1042	Missense	distal	4	no	10.963	10.478	EPSD	COSMIC	5.915	Down-regulation
CMGC_MAPK_p38_MAPK14_ST	Q09472	EP300	Q16539	MAPK14	T1135	S1136P	1136	Missense	proximal	1	no	3.172	10.456	EPSD	COSMIC	5.915	Gain
CMGC_MAPK_p38_MAPK14_ST	Q09472	EP300	Q16539	MAPK14	S1193	D1188N	1188	Missense	distal	-5	no	6.121	5.962	EPSD	COSMIC	5.915	Down-regulation
CMGC_MAPK_p38_MAPK14_ST	Q09472	EP300	Q16539	MAPK14	S1193	R1197W	1197	Missense	distal	4	no	6.121	4.847	EPSD	COSMIC	5.915	Loss
CMGC_MAPK_p38_MAPK14_ST	Q09472	EP300	Q16539	MAPK14	S1193	Q1195H	1195	Missense	proximal	2	no	6.121	6.165	EPSD	COSMIC	5.915	Up-regulation
CMGC_MAPK_p38_MAPK14_ST	Q09472	EP300	Q16539	MAPK14	T1724	S1730Y	1730	Missense	distal	6	no	7.140	7.158	EPSD	COSMIC	5.915	Up-regulation
CMGC_MAPK_p38_MAPK14_ST	Q09472	EP300	Q16539	MAPK14	T1724	S1730F	1730	Missense	distal	6	no	7.140	6.783	EPSD	COSMIC	5.915	Down-regulation
CMGC_MAPK_p38_MAPK14_ST	Q09472	EP300	Q16539	MAPK14	S1726	S1730Y	1730	Missense	distal	4	no	9.245	8.198	EPSD	COSMIC	5.915	Down-regulation
CMGC_MAPK_p38_MAPK14_ST	Q09472	EP300	Q16539	MAPK14	S1726	S1730F	1730	Missense	distal	4	no	9.245	7.671	EPSD	COSMIC	5.915	Down-regulation
CMGC_MAPK_p38_MAPK14_ST	Q09472	EP300	Q16539	MAPK14	S1726	R1732H	1732	Missense	distal	6	no	9.245	9.138	EPSD	COSMIC	5.915	Down-regulation
CMGC_MAPK_p38_MAPK14_ST	Q09472	EP300	Q16539	MAPK14	S1849	P1855S	1855	Missense	distal	6	no	9.238	9.226	EPSD	COSMIC	5.915	Down-regulation
CMGC_MAPK_p38_MAPK14_ST	Q09472	EP300	Q16539	MAPK14	S1849	G1842E	1842	Missense	distal	-7	no	9.238	9.456	EPSD	COSMIC	5.915	Up-regulation
CMGC_MAPK_p38_MAPK14_ST	Q09472	EP300	Q16539	MAPK14	S1849	P1848S	1848	Missense	proximal	-1	no	9.238	9.146	EPSD	COSMIC	5.915	Down-regulation
CMGC_MAPK_p38_MAPK14_ST	Q09472	EP300	Q16539	MAPK14	T1851	P1855S	1855	Missense	distal	4	no	9.693	10.132	EPSD	COSMIC	5.915	Up-regulation
CMGC_MAPK_p38_MAPK14_ST	Q09472	EP300	Q16539	MAPK14	T1851	T1857P	1857	Missense	distal	6	no	9.693	9.667	EPSD	COSMIC	5.915	Down-regulation
CMGC_MAPK_p38_MAPK14_ST	Q09472	EP300	Q16539	MAPK14	T1851	P1848S	1848	Missense	distal	-3	no	9.693	10.457	EPSD	COSMIC	5.915	Up-regulation
CMGC_MAPK_p38_MAPK14_ST	Q09472	EP300	Q16539	MAPK14	T1854	P1855S	1855	Missense	proximal	1	no	11.552	4.268	EPSD	COSMIC	5.915	Loss
CMGC_MAPK_p38_MAPK14_ST	Q09472	EP300	Q16539	MAPK14	T1854	T1857P	1857	Missense	distal	3	no	11.552	11.578	EPSD	COSMIC	5.915	Up-regulation
CMGC_MAPK_p38_MAPK14_ST	Q09472	EP300	Q16539	MAPK14	T1854	G1860D	1860	Missense	distal	6	no	11.552	11.410	EPSD	COSMIC	5.915	Down-regulation
CMGC_MAPK_p38_MAPK14_ST	Q09472	EP300	Q16539	MAPK14	T1854	P1848S	1848	Missense	distal	-6	no	11.552	12.159	EPSD	COSMIC	5.915	Up-regulation
CMGC_MAPK_p38_MAPK14_ST	Q09472	EP300	Q16539	MAPK14	T1856	T1857P	1857	Missense	proximal	1	no	4.394	11.847	EPSD	COSMIC	5.915	Gain
CMGC_MAPK_p38_MAPK14_ST	Q09472	EP300	Q16539	MAPK14	T1857	P1855S	1855	Missense	proximal	-2	no	10.922	10.434	EPSD	COSMIC	5.915	Down-regulation
CMGC_MAPK_p38_MAPK14_ST	Q09472	EP300	Q16539	MAPK14	T1857	T1857P	1857	Missense	central	0	yes	10.922	0.000	EPSD	COSMIC	5.915	Loss
CMGC_MAPK_p38_MAPK14_ST	Q09472	EP300	Q16539	MAPK14	T1857	G1860D	1860	Missense	distal	3	no	10.922	10.932	EPSD	COSMIC	5.915	Up-regulation
CMGC_MAPK_p38_MAPK14_ST	Q09472	EP300	Q16539	MAPK14	T1857	P1863S	1863	Missense	distal	6	no	10.922	10.911	EPSD	COSMIC	5.915	Down-regulation
CMGC_MAPK_p38_MAPK14_ST	Q09472	EP300	Q16539	MAPK14	T1857	Q1862P	1862	Missense	distal	5	no	10.922	11.131	EPSD	COSMIC	5.915	Up-regulation
CMGC_MAPK_p38_MAPK14_ST	Q09472	EP300	Q16539	MAPK14	T1865	P1869L	1869	Missense	distal	4	no	8.723	8.084	EPSD	COSMIC	5.915	Down-regulation
CMGC_MAPK_p38_MAPK14_ST	Q09472	EP300	Q16539	MAPK14	T1865	P1866L	1866	Missense	proximal	1	no	8.723	0.672	EPSD	COSMIC;CCLE	5.915	Loss
CMGC_MAPK_p38_MAPK14_ST	Q09472	EP300	Q16539	MAPK14	T1865	G1860D	1860	Missense	distal	-5	no	8.723	8.965	EPSD	COSMIC	5.915	Up-regulation
CMGC_MAPK_p38_MAPK14_ST	Q09472	EP300	Q16539	MAPK14	T1865	P1863S	1863	Missense	proximal	-2	no	8.723	8.234	EPSD	COSMIC	5.915	Down-regulation
CMGC_MAPK_p38_MAPK14_ST	Q09472	EP300	Q16539	MAPK14	T1865	Q1862P	1862	Missense	distal	-3	no	8.723	9.226	EPSD	COSMIC	5.915	Up-regulation
CMGC_MAPK_p38_MAPK14_ST	Q09472	EP300	Q16539	MAPK14	T1865	Q1867K	1867	Missense	proximal	2	no	8.723	8.946	EPSD	COSMIC	5.915	Up-regulation
CMGC_MAPK_p38_MAPK14_ST	Q09472	EP300	Q16539	MAPK14	T1906	P1907S	1907	Missense	proximal	1	no	9.300	2.016	EPSD	COSMIC	5.915	Loss
CMGC_MAPK_p38_MAPK14_ST	Q09472	EP300	Q16539	MAPK14	T1906	T1906I	1906	Missense	central	0	yes	9.300	0.000	EPSD	COSMIC	5.915	Loss
CMGC_MAPK_p38_MAPK14_ST	Q09472	EP300	Q16539	MAPK14	T1906	G1899D	1899	Missense	distal	-7	no	9.300	8.936	EPSD	COSMIC	5.915	Down-regulation
CMGC_MAPK_p38_MAPK14_ST	Q09472	EP300	Q16539	MAPK14	T1909	P1907S	1907	Missense	proximal	-2	no	11.278	10.790	EPSD	COSMIC	5.915	Down-regulation
CMGC_MAPK_p38_MAPK14_ST	Q09472	EP300	Q16539	MAPK14	T1909	T1906I	1906	Missense	distal	-3	no	11.278	9.524	EPSD	COSMIC	5.915	Down-regulation
CMGC_MAPK_p38_MAPK14_ST	Q09472	EP300	Q16539	MAPK14	T1913	P1907S	1907	Missense	distal	-6	no	5.597	6.203	EPSD	COSMIC	5.915	Gain
CMGC_MAPK_p38_MAPK14_ST	Q09472	EP300	Q16539	MAPK14	T1960	P1957A	1957	Missense	distal	-3	no	7.424	7.775	EPSD	COSMIC	5.915	Up-regulation
CMGC_MAPK_p38_MAPK14_ST	Q09472	EP300	Q16539	MAPK14	T1960	G1966S	1966	Missense	distal	6	no	7.424	7.303	EPSD	COSMIC	5.915	Down-regulation
CMGC_MAPK_p38_MAPK14_ST	Q09472	EP300	Q16539	MAPK14	T1960	P1964S	1964	Missense	distal	4	no	7.424	7.863	EPSD	COSMIC	5.915	Up-regulation
CMGC_MAPK_p38_MAPK14_ST	Q09472	EP300	Q16539	MAPK14	T1960	M1965I	1965	Missense	distal	5	no	7.424	6.810	EPSD	COSMIC	5.915	Down-regulation
CMGC_MAPK_p38_MAPK14_ST	Q09472	EP300	Q16539	MAPK14	T1960	M1965V	1965	Missense	distal	5	no	7.424	7.246	EPSD	COSMIC	5.915	Down-regulation
CMGC_MAPK_p38_MAPK14_ST	Q09472	EP300	Q16539	MAPK14	S2039	T2045S	2045	Missense	distal	6	no	10.933	10.895	EPSD	COSMIC	5.915	Down-regulation
CMGC_MAPK_p38_MAPK14_ST	Q09472	EP300	Q16539	MAPK14	S2039	I2038M	2038	Missense	proximal	-1	no	10.933	11.078	EPSD	COSMIC	5.915	Up-regulation
CMGC_MAPK_p38_MAPK14_ST	Q09472	EP300	Q16539	MAPK14	S2279	P2286S	2286	Missense	distal	7	no	10.469	10.691	EPSD	COSMIC	5.915	Up-regulation
CMGC_MAPK_p38_MAPK14_ST	Q09472	EP300	Q16539	MAPK14	S2279	P2277L	2277	Missense	proximal	-2	no	10.469	9.089	EPSD	COSMIC	5.915	Down-regulation
CMGC_MAPK_p38_MAPK14_ST	Q09472	EP300	Q16539	MAPK14	S2309	P2314T	2314	Missense	distal	5	no	7.151	7.435	EPSD	COSMIC	5.915	Up-regulation
CMGC_MAPK_p38_MAPK14_ST	Q09472	EP300	Q16539	MAPK14	S2309	L2303F	2303	Missense	distal	-6	no	7.151	6.606	EPSD	COSMIC	5.915	Down-regulation
CMGC_MAPK_p38_MAPK14_ST	Q09472	EP300	Q16539	MAPK14	S2309	Q2306H	2306	Missense	distal	-3	no	7.151	7.176	EPSD	COSMIC	5.915	Up-regulation
CMGC_MAPK_p38_MAPK14_ST	Q09472	EP300	Q16539	MAPK14	S2309	P2312S	2312	Missense	distal	3	no	7.151	7.110	EPSD	COSMIC	5.915	Down-regulation
CMGC_MAPK_p38_MAPK14_ST	Q09472	EP300	Q16539	MAPK14	S2315	P2314T	2314	Missense	proximal	-1	no	13.154	13.178	EPSD	COSMIC	5.915	Up-regulation
CMGC_MAPK_p38_MAPK14_ST	Q09472	EP300	Q16539	MAPK14	S2315	R2317W	2317	Missense	proximal	2	no	13.154	12.655	EPSD	COSMIC	5.915	Down-regulation
CMGC_MAPK_p38_MAPK14_ST	Q09472	EP300	Q16539	MAPK14	S2315	P2312S	2312	Missense	distal	-3	no	13.154	13.917	EPSD	COSMIC	5.915	Up-regulation
CMGC_MAPK_p38_MAPK14_ST	Q09472	EP300	Q16539	MAPK14	S2326	H2324T	2324	Missense	proximal	-2	no	8.849	10.396	EPSD	COSMIC	5.915	Up-regulation
CMGC_MAPK_p38_MAPK14_ST	Q09472	EP300	Q16539	MAPK14	S2326	H2324Y	2324	Missense	proximal	-2	no	8.849	10.629	EPSD	COSMIC	5.915	Up-regulation
CMGC_MAPK_p38_MAPK14_ST	Q09472	EP300	Q16539	MAPK14	S2328	H2324T	2324	Missense	distal	-4	no	13.309	13.365	EPSD	COSMIC	5.915	Up-regulation
CMGC_MAPK_p38_MAPK14_ST	Q09472	EP300	Q16539	MAPK14	S2328	H2324Y	2324	Missense	distal	-4	no	13.309	13.083	EPSD	COSMIC	5.915	Down-regulation
CMGC_MAPK_p38_MAPK14_ST	Q09472	EP300	Q16539	MAPK14	S2366	N2370I	2370	Missense	distal	4	no	11.588	11.316	EPSD	COSMIC	5.915	Down-regulation
CMGC_MAPK_p38_MAPK14_ST	Q09472	EP300	Q16539	MAPK14	S2366	M2372V	2372	Missense	distal	6	no	11.588	11.299	EPSD	COSMIC	5.915	Down-regulation
CMGC_MAPK_p38_MAPK14_ST	Q09472	EP300	Q16539	MAPK14	S2366	M2359R	2359	Missense	distal	-7	no	11.588	11.435	EPSD	COSMIC	5.915	Down-regulation
CMGC_MAPK_p38_MAPK14_ST	P15336	ATF2	Q16539	MAPK14	T69	T73A	73	Missense	distal	4	no	11.101	11.057	PhosphoSitePlus;EPSD	COSMIC	5.915	Down-regulation
CMGC_MAPK_p38_MAPK14_ST	P15336	ATF2	Q16539	MAPK14	T69	F75L	75	Missense	distal	6	no	11.101	11.331	PhosphoSitePlus;EPSD	COSMIC	5.915	Up-regulation
CMGC_MAPK_p38_MAPK14_ST	P15336	ATF2	Q16539	MAPK14	T69	R74T	74	Missense	distal	5	no	11.101	11.245	PhosphoSitePlus;EPSD	COSMIC	5.915	Up-regulation
CMGC_MAPK_p38_MAPK14_ST	P15336	ATF2	Q16539	MAPK14	T69	I64V	64	Missense	distal	-5	no	11.101	11.305	PhosphoSitePlus;EPSD	COSMIC	5.915	Up-regulation
CMGC_MAPK_p38_MAPK14_ST	P15336	ATF2	Q16539	MAPK14	T69	D67E	67	Missense	proximal	-2	no	11.101	12.530	PhosphoSitePlus;EPSD	COSMIC	5.915	Up-regulation
CMGC_MAPK_p38_MAPK14_ST	P15336	ATF2	Q16539	MAPK14	T71	T73A	73	Missense	proximal	2	no	9.601	9.572	EPSD;PhosphoSitePlus	COSMIC	5.915	Down-regulation
CMGC_MAPK_p38_MAPK14_ST	P15336	ATF2	Q16539	MAPK14	T71	F75L	75	Missense	distal	4	no	9.601	10.096	EPSD;PhosphoSitePlus	COSMIC	5.915	Up-regulation
CMGC_MAPK_p38_MAPK14_ST	P15336	ATF2	Q16539	MAPK14	T71	R74T	74	Missense	distal	3	no	9.601	9.586	EPSD;PhosphoSitePlus	COSMIC	5.915	Down-regulation
CMGC_MAPK_p38_MAPK14_ST	P15336	ATF2	Q16539	MAPK14	T71	I64V	64	Missense	distal	-7	no	9.601	9.317	EPSD;PhosphoSitePlus	COSMIC	5.915	Down-regulation
CMGC_MAPK_p38_MAPK14_ST	P15336	ATF2	Q16539	MAPK14	T71	D67E	67	Missense	distal	-4	no	9.601	8.809	EPSD;PhosphoSitePlus	COSMIC	5.915	Down-regulation
CMGC_MAPK_p38_MAPK14_ST	P15336	ATF2	Q16539	MAPK14	S90	P91S	91	Missense	proximal	1	no	10.813	3.530	EPSD	COSMIC	5.915	Loss
CMGC_MAPK_p38_MAPK14_ST	P15336	ATF2	Q16539	MAPK14	S90	A89V	89	Missense	proximal	-1	no	10.813	10.969	EPSD	COSMIC	5.915	Up-regulation
CMGC_MAPK_p38_MAPK14_ST	P15336	ATF2	Q16539	MAPK14	S90	P91L	91	Missense	proximal	1	no	10.813	2.763	EPSD	COSMIC	5.915	Loss
CMGC_MAPK_p38_MAPK14_ST	P15336	ATF2	Q16539	MAPK14	S90	G83C	83	Missense	distal	-7	no	10.813	10.320	EPSD	COSMIC	5.915	Down-regulation
CMGC_MAPK_p38_MAPK14_ST	P15336	ATF2	Q16539	MAPK14	S112	M107I	107	Missense	distal	-5	no	6.930	7.177	EPSD	COSMIC;GDSC;CCLE	5.915	Up-regulation
CMGC_MAPK_p38_MAPK14_ST	P15336	ATF2	Q16539	MAPK14	S112	K105T	105	Missense	distal	-7	no	6.930	6.763	EPSD	COSMIC;GDSC;CCLE	5.915	Down-regulation
CMGC_MAPK_p38_MAPK14_ST	P15336	ATF2	Q16539	MAPK14	S112	K106R	106	Missense	distal	-6	no	6.930	7.408	EPSD	COSMIC	5.915	Up-regulation
CMGC_MAPK_p38_MAPK14_ST	P15336	ATF2	Q16539	MAPK14	S112	D110E	110	Missense	proximal	-2	no	6.930	8.358	EPSD	COSMIC	5.915	Up-regulation
CMGC_MAPK_p38_MAPK14_ST	P15336	ATF2	Q16539	MAPK14	T116	D110E	110	Missense	distal	-6	no	6.954	7.533	EPSD	COSMIC	5.915	Up-regulation
CMGC_MAPK_p38_MAPK14_ST	P15336	ATF2	Q16539	MAPK14	S136	P141T	141	Missense	distal	5	no	8.563	8.847	EPSD	COSMIC	5.915	Up-regulation
CMGC_MAPK_p38_MAPK14_ST	P15336	ATF2	Q16539	MAPK14	S136	P141L	141	Missense	distal	5	no	8.563	8.066	EPSD	COSMIC	5.915	Down-regulation
CMGC_MAPK_p38_MAPK14_ST	P15336	ATF2	Q16539	MAPK14	S136	P137S	137	Missense	proximal	1	no	8.563	1.280	EPSD	COSMIC	5.915	Loss
CMGC_MAPK_p38_MAPK14_ST	P15336	ATF2	Q16539	MAPK14	S265	S266P	266	Missense	proximal	1	no	1.513	8.797	EPSD	COSMIC	5.915	Gain
CMGC_MAPK_p38_MAPK14_ST	P15336	ATF2	Q16539	MAPK14	S266	S266P	266	Missense	central	0	yes	10.420	0.000	EPSD	COSMIC	5.915	Loss
CMGC_MAPK_p38_MAPK14_ST	P15336	ATF2	Q16539	MAPK14	S266	P269Q	269	Missense	distal	3	no	10.420	10.448	EPSD	COSMIC	5.915	Up-regulation
CMGC_MAPK_p38_MAPK14_ST	P15336	ATF2	Q16539	MAPK14	S266	S265F	265	Missense	proximal	-1	no	10.420	10.662	EPSD	COSMIC;GDSC;CCLE	5.915	Up-regulation
CMGC_MAPK_p38_MAPK14_ST	P15336	ATF2	Q16539	MAPK14	S266	P269S	269	Missense	distal	3	no	10.420	10.380	EPSD	COSMIC	5.915	Down-regulation
CMGC_MAPK_p38_MAPK14_ST	P15336	ATF2	Q16539	MAPK14	S307	T305I	305	Missense	proximal	-2	no	8.199	8.100	EPSD	COSMIC	5.915	Down-regulation
CMGC_MAPK_p38_MAPK14_ST	P15336	ATF2	Q16539	MAPK14	S307	R311Q	311	Missense	distal	4	no	8.199	7.994	EPSD	COSMIC;GDSC;CCLE	5.915	Down-regulation
CMGC_MAPK_p38_MAPK14_ST	P15336	ATF2	Q16539	MAPK14	T320	P326L	326	Missense	distal	6	no	7.720	7.581	EPSD	COSMIC;GDSC	5.915	Down-regulation
CMGC_MAPK_p38_MAPK14_ST	P15336	ATF2	Q16539	MAPK14	T320	P326T	326	Missense	distal	6	no	7.720	7.746	EPSD	COSMIC	5.915	Up-regulation
CMGC_MAPK_p38_MAPK14_ST	P15336	ATF2	Q16539	MAPK14	T320	Q316K	316	Missense	distal	-4	no	7.720	7.268	EPSD	COSMIC	5.915	Down-regulation
CMGC_MAPK_p38_MAPK14_ST	P15336	ATF2	Q16539	MAPK14	T320	Q317H	317	Missense	distal	-3	no	7.720	7.746	EPSD	COSMIC	5.915	Up-regulation
CMGC_MAPK_p38_MAPK14_ST	P15336	ATF2	Q16539	MAPK14	T325	P326L	326	Missense	proximal	1	no	9.210	1.159	EPSD	COSMIC;GDSC	5.915	Loss
CMGC_MAPK_p38_MAPK14_ST	P15336	ATF2	Q16539	MAPK14	T325	P326T	326	Missense	proximal	1	no	9.210	1.756	EPSD	COSMIC	5.915	Loss
CMGC_MAPK_p38_MAPK14_ST	P15336	ATF2	Q16539	MAPK14	T325	H331Y	331	Missense	distal	6	no	9.210	9.336	EPSD	COSMIC	5.915	Up-regulation
CMGC_MAPK_p38_MAPK14_ST	P15336	ATF2	Q16539	MAPK14	S328	P326L	326	Missense	proximal	-2	no	11.961	10.581	EPSD	COSMIC;GDSC	5.915	Down-regulation
CMGC_MAPK_p38_MAPK14_ST	P15336	ATF2	Q16539	MAPK14	S328	P326T	326	Missense	proximal	-2	no	11.961	11.242	EPSD	COSMIC	5.915	Down-regulation
CMGC_MAPK_p38_MAPK14_ST	P15336	ATF2	Q16539	MAPK14	S328	Q335H	335	Missense	distal	7	no	11.961	11.621	EPSD	COSMIC	5.915	Down-regulation
CMGC_MAPK_p38_MAPK14_ST	P15336	ATF2	Q16539	MAPK14	S328	P334S	334	Missense	distal	6	no	11.961	11.950	EPSD	COSMIC	5.915	Down-regulation
CMGC_MAPK_p38_MAPK14_ST	P15336	ATF2	Q16539	MAPK14	S328	H331Y	331	Missense	distal	3	no	11.961	11.904	EPSD	COSMIC	5.915	Down-regulation
CMGC_MAPK_p38_MAPK14_ST	P15336	ATF2	Q16539	MAPK14	T333	Q337K	337	Missense	distal	4	no	10.979	11.934	EPSD	COSMIC	5.915	Up-regulation
CMGC_MAPK_p38_MAPK14_ST	P15336	ATF2	Q16539	MAPK14	T333	P326L	326	Missense	distal	-7	no	10.979	10.786	EPSD	COSMIC;GDSC	5.915	Down-regulation
CMGC_MAPK_p38_MAPK14_ST	P15336	ATF2	Q16539	MAPK14	T333	P326T	326	Missense	distal	-7	no	10.979	10.997	EPSD	COSMIC	5.915	Up-regulation
CMGC_MAPK_p38_MAPK14_ST	P15336	ATF2	Q16539	MAPK14	T333	Q335H	335	Missense	proximal	2	no	10.979	11.023	EPSD	COSMIC	5.915	Up-regulation
CMGC_MAPK_p38_MAPK14_ST	P15336	ATF2	Q16539	MAPK14	T333	P334S	334	Missense	proximal	1	no	10.979	3.696	EPSD	COSMIC	5.915	Loss
CMGC_MAPK_p38_MAPK14_ST	P15336	ATF2	Q16539	MAPK14	T333	H331Y	331	Missense	proximal	-2	no	10.979	12.760	EPSD	COSMIC	5.915	Up-regulation
CMGC_MAPK_p38_MAPK14_ST	P15336	ATF2	Q16539	MAPK14	T336	Q337K	337	Missense	proximal	1	no	6.363	4.564	EPSD	COSMIC	5.915	Loss
CMGC_MAPK_p38_MAPK14_ST	P15336	ATF2	Q16539	MAPK14	T336	Q335H	335	Missense	proximal	-1	no	6.363	6.430	EPSD	COSMIC	5.915	Up-regulation
CMGC_MAPK_p38_MAPK14_ST	P15336	ATF2	Q16539	MAPK14	T336	R343L	343	Missense	distal	7	no	6.363	5.944	EPSD	COSMIC	5.915	Down-regulation
CMGC_MAPK_p38_MAPK14_ST	P15336	ATF2	Q16539	MAPK14	T336	P334S	334	Missense	proximal	-2	no	6.363	5.875	EPSD	COSMIC	5.915	Loss
CMGC_MAPK_p38_MAPK14_ST	P15336	ATF2	Q16539	MAPK14	T336	H331Y	331	Missense	distal	-5	no	6.363	6.050	EPSD	COSMIC	5.915	Down-regulation
CMGC_MAPK_p38_MAPK14_ST	P15336	ATF2	Q16539	MAPK14	T336	R343Q	343	Missense	distal	7	no	6.363	6.169	EPSD	COSMIC	5.915	Down-regulation
CMGC_MAPK_p38_MAPK14_ST	P15336	ATF2	Q16539	MAPK14	S446	S442L	442	Missense	distal	-4	no	9.742	10.342	EPSD	COSMIC	5.915	Up-regulation
CMGC_MAPK_p38_MAPK14_ST	P15336	ATF2	Q16539	MAPK14	S446	P444L	444	Missense	proximal	-2	no	9.742	8.362	EPSD	COSMIC	5.915	Down-regulation
CMGC_MAPK_p38_MAPK14_ST	P15336	ATF2	Q16539	MAPK14	S446	P444T	444	Missense	proximal	-2	no	9.742	9.022	EPSD	COSMIC	5.915	Down-regulation
CMGC_MAPK_p38_MAPK14_ST	P15336	ATF2	Q16539	MAPK14	S446	S442P	442	Missense	distal	-4	no	9.742	9.829	EPSD	COSMIC	5.915	Up-regulation
CMGC_MAPK_p38_MAPK14_ST	P15336	ATF2	Q16539	MAPK14	S446	P444Q	444	Missense	proximal	-2	no	9.742	8.727	EPSD	COSMIC	5.915	Down-regulation
CMGC_MAPK_p38_MAPK14_ST	P15336	ATF2	Q16539	MAPK14	S497	Q501K	501	Missense	distal	4	no	5.113	6.068	EPSD	COSMIC	5.915	Gain
CMGC_MAPK_p38_MAPK14_ST	P15336	ATF2	Q16539	MAPK14	S498	V493I	493	Missense	distal	-5	no	6.203	5.999	EPSD	COSMIC	5.915	Down-regulation
CMGC_MAPK_p38_MAPK14_ST	P15336	ATF2	Q16539	MAPK14	S498	Q501K	501	Missense	distal	3	no	6.203	6.178	EPSD	COSMIC	5.915	Down-regulation
CMGC_MAPK_p38_MAPK14_ST	Q9NRR4	DROSHA	Q16539	MAPK14	S201	L207F	207	Missense	distal	6	no	9.068	8.838	EPSD	COSMIC	5.915	Down-regulation
CMGC_MAPK_p38_MAPK14_ST	Q9NRR4	DROSHA	Q16539	MAPK14	S201	N198K	198	Missense	distal	-3	no	9.068	9.040	EPSD	COSMIC	5.915	Down-regulation
CMGC_MAPK_p38_MAPK14_ST	Q9NRR4	DROSHA	Q16539	MAPK14	S221	K214N	214	Missense	distal	-7	no	11.714	11.406	EPSD;PhosphoSitePlus	COSMIC;GDSC;CCLE	5.915	Down-regulation
CMGC_MAPK_p38_MAPK14_ST	Q9NRR4	DROSHA	Q16539	MAPK14	S221	P216A	216	Missense	distal	-5	no	11.714	11.378	EPSD;PhosphoSitePlus	COSMIC	5.915	Down-regulation
CMGC_MAPK_p38_MAPK14_ST	Q9NRR4	DROSHA	Q16539	MAPK14	S221	L225Q	225	Missense	distal	4	no	11.714	11.871	EPSD;PhosphoSitePlus	COSMIC	5.915	Up-regulation
CMGC_MAPK_p38_MAPK14_ST	Q9NRR4	DROSHA	Q16539	MAPK14	S221	R219I	219	Missense	proximal	-2	no	11.714	11.584	EPSD;PhosphoSitePlus	COSMIC;GDSC;CCLE	5.915	Down-regulation
CMGC_MAPK_p38_MAPK14_ST	Q9NRR4	DROSHA	Q16539	MAPK14	S255	R254H	254	Missense	proximal	-1	no	9.921	10.076	PhosphoSitePlus;EPSD	COSMIC	5.915	Up-regulation
CMGC_MAPK_p38_MAPK14_ST	Q9NRR4	DROSHA	Q16539	MAPK14	S255	E251G	251	Missense	distal	-4	no	9.921	10.218	PhosphoSitePlus;EPSD	COSMIC	5.915	Up-regulation
CMGC_MAPK_p38_MAPK14_ST	Q9NRR4	DROSHA	Q16539	MAPK14	S255	R252Q	252	Missense	distal	-3	no	9.921	8.142	PhosphoSitePlus;EPSD	COSMIC	5.915	Down-regulation
CMGC_MAPK_p38_MAPK14_ST	Q9NRR4	DROSHA	Q16539	MAPK14	T274	R279C	279	Missense	distal	5	no	11.616	10.746	EPSD;PhosphoSitePlus	COSMIC	5.915	Down-regulation
CMGC_MAPK_p38_MAPK14_ST	Q9NRR4	DROSHA	Q16539	MAPK14	T274	R277C	277	Missense	distal	3	no	11.616	11.672	EPSD;PhosphoSitePlus	COSMIC	5.915	Up-regulation
CMGC_MAPK_p38_MAPK14_ST	Q9NRR4	DROSHA	Q16539	MAPK14	T274	S276C	276	Missense	proximal	2	no	11.616	11.203	EPSD;PhosphoSitePlus	COSMIC	5.915	Down-regulation
CMGC_MAPK_p38_MAPK14_ST	Q9NRR4	DROSHA	Q16539	MAPK14	T274	R279H	279	Missense	distal	5	no	11.616	10.921	EPSD;PhosphoSitePlus	COSMIC;GDSC;CCLE	5.915	Down-regulation
CMGC_MAPK_p38_MAPK14_ST	Q9NRR4	DROSHA	Q16539	MAPK14	T274	H278R	278	Missense	distal	4	no	11.616	12.009	EPSD;PhosphoSitePlus	COSMIC	5.915	Up-regulation
CMGC_MAPK_p38_MAPK14_ST	Q9NRR4	DROSHA	Q16539	MAPK14	S300	S302C	302	Missense	proximal	2	no	12.619	12.206	EPSD;PhosphoSitePlus	COSMIC	5.915	Down-regulation
CMGC_MAPK_p38_MAPK14_ST	Q9NRR4	DROSHA	Q16539	MAPK14	T330	P324S	324	Missense	distal	-6	no	11.414	12.021	EPSD	COSMIC	5.915	Up-regulation
CMGC_MAPK_p38_MAPK14_ST	Q9NRR4	DROSHA	Q16539	MAPK14	T330	E332D	332	Missense	proximal	2	no	11.414	10.963	EPSD	COSMIC	5.915	Down-regulation
CMGC_MAPK_p38_MAPK14_ST	Q9NRR4	DROSHA	Q16539	MAPK14	S355	I350M	350	Missense	distal	-5	no	9.148	8.900	EPSD;PhosphoSitePlus	COSMIC	5.915	Down-regulation
CMGC_MAPK_p38_MAPK14_ST	Q9NRR4	DROSHA	Q16539	MAPK14	S373	E368K	368	Missense	distal	-5	no	5.685	6.019	EPSD	COSMIC	5.915	Gain
CMGC_MAPK_p38_MAPK14_ST	Q9NRR4	DROSHA	Q16539	MAPK14	S807	P808S	808	Missense	proximal	1	no	12.762	5.478	EPSD	COSMIC	5.915	Loss
CMGC_MAPK_p38_MAPK14_ST	Q9NRR4	DROSHA	Q16539	MAPK14	S807	L803I	803	Missense	distal	-4	no	12.762	12.329	EPSD	COSMIC	5.915	Down-regulation
CMGC_MAPK_p38_MAPK14_ST	Q9NRR4	DROSHA	Q16539	MAPK14	T958	R961K	961	Missense	distal	3	no	6.717	6.733	EPSD	COSMIC	5.915	Up-regulation
CMGC_MAPK_p38_MAPK14_ST	P42224	STAT1	Q16539	MAPK14	T489	P491L	491	Missense	proximal	2	no	8.681	8.568	EPSD	COSMIC	5.915	Down-regulation
CMGC_MAPK_p38_MAPK14_ST	P42224	STAT1	Q16539	MAPK14	T489	P491A	491	Missense	proximal	2	no	8.681	8.794	EPSD	COSMIC;GDSC	5.915	Up-regulation
CMGC_MAPK_p38_MAPK14_ST	P42224	STAT1	Q16539	MAPK14	S532	D534Y	534	Missense	proximal	2	no	6.527	6.688	EPSD	COSMIC	5.915	Up-regulation
CMGC_MAPK_p38_MAPK14_ST	P42224	STAT1	Q16539	MAPK14	S727	E730K	730	Missense	distal	3	no	12.060	12.108	PhosphoSitePlus	COSMIC	5.915	Up-regulation
CMGC_MAPK_p38_MAPK14_ST	Q99958	FOXC2	Q16539	MAPK14	S36	G39D	39	Missense	distal	3	no	9.686	9.696	EPSD	COSMIC	5.915	Up-regulation
CMGC_MAPK_p38_MAPK14_ST	Q99958	FOXC2	Q16539	MAPK14	S36	G43D	43	Missense	distal	7	no	9.686	9.853	EPSD	COSMIC	5.915	Up-regulation
CMGC_MAPK_p38_MAPK14_ST	Q99958	FOXC2	Q16539	MAPK14	T197	T197N	197	Missense	central	0	yes	13.330	0.000	EPSD	COSMIC	5.915	Loss
CMGC_MAPK_p38_MAPK14_ST	Q99958	FOXC2	Q16539	MAPK14	T197	A203D	203	Missense	distal	6	no	13.330	13.254	EPSD	COSMIC	5.915	Down-regulation
CMGC_MAPK_p38_MAPK14_ST	Q99958	FOXC2	Q16539	MAPK14	S219	P223T	223	Missense	distal	4	no	8.063	8.241	EPSD	COSMIC	5.915	Up-regulation
CMGC_MAPK_p38_MAPK14_ST	Q99958	FOXC2	Q16539	MAPK14	S232	A236S	236	Missense	distal	4	no	10.614	10.919	EPSD	COSMIC	5.915	Up-regulation
CMGC_MAPK_p38_MAPK14_ST	Q99958	FOXC2	Q16539	MAPK14	S235	A236S	236	Missense	proximal	1	no	6.420	5.455	EPSD	COSMIC	5.915	Loss
CMGC_MAPK_p38_MAPK14_ST	Q99958	FOXC2	Q16539	MAPK14	S240	A236S	236	Missense	distal	-4	no	9.958	9.918	EPSD	COSMIC	5.915	Down-regulation
CMGC_MAPK_p38_MAPK14_ST	Q99958	FOXC2	Q16539	MAPK14	S281	M276V	276	Missense	distal	-5	no	9.993	10.445	EPSD	COSMIC;CCLE	5.915	Up-regulation
CMGC_MAPK_p38_MAPK14_ST	Q99958	FOXC2	Q16539	MAPK14	S281	G285R	285	Missense	distal	4	no	9.993	9.509	EPSD	COSMIC	5.915	Down-regulation
CMGC_MAPK_p38_MAPK14_ST	Q99958	FOXC2	Q16539	MAPK14	S288	G285R	285	Missense	distal	-3	no	14.673	16.123	EPSD	COSMIC	5.915	Up-regulation
CMGC_MAPK_p38_MAPK14_ST	Q99958	FOXC2	Q16539	MAPK14	S288	A291G	291	Missense	distal	3	no	14.673	14.700	EPSD	COSMIC	5.915	Up-regulation
CMGC_MAPK_p38_MAPK14_ST	Q99958	FOXC2	Q16539	MAPK14	S367	P365L	365	Missense	proximal	-2	no	9.892	8.512	PhosphoSitePlus	COSMIC	5.915	Down-regulation
CMGC_MAPK_p38_MAPK14_ST	Q99958	FOXC2	Q16539	MAPK14	S367	D360H	360	Missense	distal	-7	no	9.892	9.859	PhosphoSitePlus	COSMIC	5.915	Down-regulation
CMGC_MAPK_p38_MAPK14_ST	Q99958	FOXC2	Q16539	MAPK14	T484	H490Y	490	Missense	distal	6	no	10.131	10.257	EPSD	COSMIC;CCLE	5.915	Up-regulation
CMGC_MAPK_p38_MAPK14_ST	Q99958	FOXC2	Q16539	MAPK14	T484	P486T	486	Missense	proximal	2	no	10.131	10.272	EPSD	COSMIC	5.915	Up-regulation
CMGC_MAPK_p38_MAPK14_ST	Q99958	FOXC2	Q16539	MAPK14	T484	P480R	480	Missense	distal	-4	no	10.131	10.054	EPSD	COSMIC	5.915	Down-regulation
CMGC_MAPK_p38_MAPK14_ST	Q99958	FOXC2	Q16539	MAPK14	T484	A491T	491	Missense	distal	7	no	10.131	9.788	EPSD	COSMIC	5.915	Down-regulation
CMGC_MAPK_p38_MAPK14_ST	Q99958	FOXC2	Q16539	MAPK14	T484	S483F	483	Missense	proximal	-1	no	10.131	10.373	EPSD	COSMIC	5.915	Up-regulation
CMGC_MAPK_p38_MAPK14_ST	Q99958	FOXC2	Q16539	MAPK14	T484	A491V	491	Missense	distal	7	no	10.131	10.022	EPSD	COSMIC	5.915	Down-regulation
CMGC_MAPK_p38_MAPK14_ST	P36956	SREBF1	Q16539	MAPK14	T105	P99S	99	Missense	distal	-6	no	9.499	10.106	EPSD	COSMIC	5.915	Up-regulation
CMGC_MAPK_p38_MAPK14_ST	P36956	SREBF1	Q16539	MAPK14	T105	S112A	112	Missense	distal	7	no	9.499	9.522	EPSD	COSMIC	5.915	Up-regulation
CMGC_MAPK_p38_MAPK14_ST	P36956	SREBF1	Q16539	MAPK14	T105	P111L	111	Missense	distal	6	no	9.499	9.360	EPSD	COSMIC	5.915	Down-regulation
CMGC_MAPK_p38_MAPK14_ST	P36956	SREBF1	Q16539	MAPK14	T105	Y110C	110	Missense	distal	5	no	9.499	8.598	EPSD	COSMIC	5.915	Down-regulation
CMGC_MAPK_p38_MAPK14_ST	P36956	SREBF1	Q16539	MAPK14	T105	P106H	106	Missense	proximal	1	no	9.499	-4.154	EPSD	COSMIC	5.915	Loss
CMGC_MAPK_p38_MAPK14_ST	P36956	SREBF1	Q16539	MAPK14	S117	K123E	123	Missense	distal	6	no	9.578	9.583	EPSD	COSMIC	5.915	Up-regulation
CMGC_MAPK_p38_MAPK14_ST	P36956	SREBF1	Q16539	MAPK14	S117	S112A	112	Missense	distal	-5	no	9.578	9.689	EPSD	COSMIC	5.915	Up-regulation
CMGC_MAPK_p38_MAPK14_ST	P36956	SREBF1	Q16539	MAPK14	S117	P111L	111	Missense	distal	-6	no	9.578	8.964	EPSD	COSMIC	5.915	Down-regulation
CMGC_MAPK_p38_MAPK14_ST	P36956	SREBF1	Q16539	MAPK14	S117	Y110C	110	Missense	distal	-7	no	9.578	9.577	EPSD	COSMIC	5.915	Down-regulation
CMGC_MAPK_p38_MAPK14_ST	P36956	SREBF1	Q16539	MAPK14	S117	G119W	119	Missense	proximal	2	no	9.578	9.163	EPSD	COSMIC	5.915	Down-regulation
CMGC_MAPK_p38_MAPK14_ST	P36956	SREBF1	Q16539	MAPK14	T426	E420K	420	Missense	distal	-6	no	11.359	10.944	EPSD;PhosphoSitePlus	COSMIC	5.915	Down-regulation
CMGC_MAPK_p38_MAPK14_ST	P36956	SREBF1	Q16539	MAPK14	T426	D423G	423	Missense	distal	-3	no	11.359	11.409	EPSD;PhosphoSitePlus	COSMIC	5.915	Up-regulation
CMGC_MAPK_p38_MAPK14_ST	P36956	SREBF1	Q16539	MAPK14	S434	P440H	440	Missense	distal	6	no	9.802	9.683	EPSD	COSMIC	5.915	Down-regulation
CMGC_MAPK_p38_MAPK14_ST	P36956	SREBF1	Q16539	MAPK14	S439	L443F	443	Missense	distal	4	no	8.947	8.452	EPSD	COSMIC	5.915	Down-regulation
CMGC_MAPK_p38_MAPK14_ST	P36956	SREBF1	Q16539	MAPK14	S439	P440H	440	Missense	proximal	1	no	8.947	-4.706	EPSD	COSMIC	5.915	Loss
CMGC_MAPK_p38_MAPK14_ST	P36956	SREBF1	Q16539	MAPK14	S461	G454D	454	Missense	distal	-7	no	11.989	11.625	EPSD	COSMIC	5.915	Down-regulation
CMGC_MAPK_p38_MAPK14_ST	P36956	SREBF1	Q16539	MAPK14	S461	P459H	459	Missense	proximal	-2	no	11.989	9.722	EPSD	COSMIC	5.915	Down-regulation
CMGC_MAPK_p38_MAPK14_ST	P36956	SREBF1	Q16539	MAPK14	S524	S520N	520	Missense	distal	-4	no	9.309	9.382	EPSD	COSMIC	5.915	Up-regulation
CMGC_MAPK_p38_MAPK14_ST	P36956	SREBF1	Q16539	MAPK14	S524	G531A	531	Missense	distal	7	no	9.309	9.475	EPSD	COSMIC	5.915	Up-regulation
CMGC_MAPK_p38_MAPK14_ST	P36956	SREBF1	Q16539	MAPK14	S524	H523N	523	Missense	proximal	-1	no	9.309	9.333	EPSD	COSMIC	5.915	Up-regulation
CMGC_MAPK_p38_MAPK14_ST	P36956	SREBF1	Q16539	MAPK14	S1049	T1051I	1051	Missense	proximal	2	no	11.266	11.022	EPSD	COSMIC	5.915	Down-regulation
CMGC_MAPK_p38_MAPK14_ST	P36956	SREBF1	Q16539	MAPK14	S1049	A1046V	1046	Missense	distal	-3	no	11.266	9.765	EPSD	COSMIC	5.915	Down-regulation
CMGC_MAPK_p38_MAPK14_ST	P36956	SREBF1	Q16539	MAPK14	S1049	G1047W	1047	Missense	proximal	-2	no	11.266	10.990	EPSD	COSMIC	5.915	Down-regulation
CMGC_MAPK_p38_MAPK14_ST	P14598	NCF1	Q16539	MAPK14	S345	P349R	349	Missense	distal	4	no	10.832	10.555	EPSD;PhosphoSitePlus	COSMIC	5.915	Down-regulation
CMGC_MAPK_p38_MAPK14_ST	P14598	NCF1	Q16539	MAPK14	S348	P349R	349	Missense	proximal	1	no	13.932	5.996	PhosphoSitePlus;EPSD	COSMIC	5.915	Down-regulation
CMGC_MAPK_p38_MAPK14_ST	P38936	CDKN1A	Q16539	MAPK14	T57	D62Y	62	Missense	distal	5	no	8.710	8.975	EPSD;PhosphoSitePlus	COSMIC	5.915	Up-regulation
CMGC_MAPK_p38_MAPK14_ST	P38936	CDKN1A	Q16539	MAPK14	T57	D62H	62	Missense	distal	5	no	8.710	8.249	EPSD;PhosphoSitePlus	COSMIC	5.915	Down-regulation
CMGC_MAPK_p38_MAPK14_ST	P38936	CDKN1A	Q16539	MAPK14	T57	D52V	52	Missense	distal	-5	no	8.710	8.690	EPSD;PhosphoSitePlus	COSMIC	5.915	Down-regulation
CMGC_MAPK_p38_MAPK14_ST	P38936	CDKN1A	Q16539	MAPK14	T57	T57R	57	Missense	central	0	yes	8.710	0.000	EPSD;PhosphoSitePlus	COSMIC	5.915	Loss
CMGC_MAPK_p38_MAPK14_ST	P38936	CDKN1A	Q16539	MAPK14	S98	T97I	97	Missense	proximal	-1	no	8.521	8.383	EPSD;PhosphoSitePlus	COSMIC	5.915	Down-regulation
CMGC_MAPK_p38_MAPK14_ST	P38936	CDKN1A	Q16539	MAPK14	S130	E125Q	125	Missense	distal	-5	no	13.304	13.731	PhosphoSitePlus;EPSD	COSMIC	5.915	Up-regulation
CMGC_MAPK_p38_MAPK14_ST	P38936	CDKN1A	Q16539	MAPK14	S130	S137T	137	Missense	distal	7	no	13.304	12.983	PhosphoSitePlus;EPSD	COSMIC	5.915	Down-regulation
CMGC_MAPK_p38_MAPK14_ST	Q15750	TAB1	Q16539	MAPK14	S339	A343T	343	Missense	distal	4	no	6.260	6.304	EPSD	COSMIC	5.915	Up-regulation
CMGC_MAPK_p38_MAPK14_ST	Q15750	TAB1	Q16539	MAPK14	T376	M372I	372	Missense	distal	-4	no	11.469	11.565	EPSD	COSMIC	5.915	Up-regulation
CMGC_MAPK_p38_MAPK14_ST	Q15750	TAB1	Q16539	MAPK14	T376	S373G	373	Missense	distal	-3	no	11.469	10.531	EPSD	COSMIC	5.915	Down-regulation
CMGC_MAPK_p38_MAPK14_ST	Q15750	TAB1	Q16539	MAPK14	T376	E371K	371	Missense	distal	-5	no	11.469	11.803	EPSD	COSMIC	5.915	Up-regulation
CMGC_MAPK_p38_MAPK14_ST	Q15750	TAB1	Q16539	MAPK14	S378	M372I	372	Missense	distal	-6	no	10.594	10.159	EPSD	COSMIC	5.915	Down-regulation
CMGC_MAPK_p38_MAPK14_ST	Q15750	TAB1	Q16539	MAPK14	S378	S373G	373	Missense	distal	-5	no	10.594	10.975	EPSD	COSMIC	5.915	Up-regulation
CMGC_MAPK_p38_MAPK14_ST	Q15750	TAB1	Q16539	MAPK14	S378	E371K	371	Missense	distal	-7	no	10.594	10.540	EPSD	COSMIC	5.915	Down-regulation
CMGC_MAPK_p38_MAPK14_ST	Q15750	TAB1	Q16539	MAPK14	T431	T435I	435	Missense	distal	4	no	10.605	10.077	EPSD;PhosphoSitePlus	COSMIC	5.915	Down-regulation
CMGC_MAPK_p38_MAPK14_ST	Q15750	TAB1	Q16539	MAPK14	T431	Q437K	437	Missense	distal	6	no	10.605	10.667	EPSD;PhosphoSitePlus	COSMIC	5.915	Up-regulation
CMGC_MAPK_p38_MAPK14_ST	Q15750	TAB1	Q16539	MAPK14	S438	P439L	439	Missense	proximal	1	no	11.609	3.558	EPSD;PhosphoSitePlus	COSMIC	5.915	Loss
CMGC_MAPK_p38_MAPK14_ST	Q15750	TAB1	Q16539	MAPK14	S438	T435I	435	Missense	distal	-3	no	11.609	9.855	EPSD;PhosphoSitePlus	COSMIC	5.915	Down-regulation
CMGC_MAPK_p38_MAPK14_ST	Q15750	TAB1	Q16539	MAPK14	S438	Q437K	437	Missense	proximal	-1	no	11.609	11.602	EPSD;PhosphoSitePlus	COSMIC	5.915	Down-regulation
CMGC_MAPK_p38_MAPK14_ST	Q15750	TAB1	Q16539	MAPK14	S453	T446I	446	Missense	distal	-7	no	6.000	5.649	EPSD;PhosphoSitePlus	COSMIC	5.915	Loss
CMGC_MAPK_p38_MAPK14_ST	Q15750	TAB1	Q16539	MAPK14	S492	Y488C	488	Missense	distal	-4	no	5.782	6.248	EPSD	COSMIC	5.915	Gain
CMGC_MAPK_p38_MAPK14_ST	Q15750	TAB1	Q16539	MAPK14	S499	V500M	500	Missense	proximal	1	no	3.828	5.942	EPSD	COSMIC	5.915	Gain
CMGC_MAPK_p38_MAPK14_ST	Q8WYK2	JDP2	Q16539	MAPK14	T143	R136H	136	Missense	distal	-7	no	6.578	6.284	EPSD	COSMIC	5.915	Down-regulation
CMGC_MAPK_p38_MAPK14_ST	Q8WYK2	JDP2	Q16539	MAPK14	T143	C139Y	139	Missense	distal	-4	no	6.578	6.113	EPSD	COSMIC	5.915	Down-regulation
CMGC_MAPK_p38_MAPK14_ST	Q8WYK2	JDP2	Q16539	MAPK14	T143	D144N	144	Missense	proximal	1	no	6.578	6.206	EPSD	COSMIC	5.915	Down-regulation
CMGC_MAPK_p38_MAPK14_ST	Q8WYK2	JDP2	Q16539	MAPK14	T143	R136C	136	Missense	distal	-7	no	6.578	6.186	EPSD	COSMIC	5.915	Down-regulation
CMGC_MAPK_p38_MAPK14_ST	Q8WYK2	JDP2	Q16539	MAPK14	T143	T138I	138	Missense	distal	-5	no	6.578	6.537	EPSD	COSMIC	5.915	Down-regulation
CMGC_MAPK_p38_MAPK14_ST	Q8WYK2	JDP2	Q16539	MAPK14	T148	D144N	144	Missense	distal	-4	no	10.947	10.527	PhosphoSitePlus	COSMIC	5.915	Down-regulation
CMGC_MAPK_p38_MAPK14_ST	Q8WYK2	JDP2	Q16539	MAPK14	S151	D144N	144	Missense	distal	-7	no	6.420	6.640	EPSD	COSMIC	5.915	Up-regulation
CMGC_MAPK_p38_MAPK14_ST	P78536	ADAM17	Q16539	MAPK14	S266	I261M	261	Missense	distal	-5	no	7.242	6.995	EPSD	COSMIC	5.915	Down-regulation
CMGC_MAPK_p38_MAPK14_ST	Q14721	KCNB1	Q16539	MAPK14	S484	H482Y	482	Missense	proximal	-2	no	4.553	6.333	EPSD	COSMIC	5.915	Gain
CMGC_MAPK_p38_MAPK14_ST	Q14721	KCNB1	Q16539	MAPK14	S496	K492N	492	Missense	distal	-4	no	6.348	6.494	EPSD	COSMIC	5.915	Up-regulation
CMGC_MAPK_p38_MAPK14_ST	Q14721	KCNB1	Q16539	MAPK14	S520	V526I	526	Missense	distal	6	no	9.837	9.867	EPSD	COSMIC	5.915	Up-regulation
CMGC_MAPK_p38_MAPK14_ST	Q14721	KCNB1	Q16539	MAPK14	S520	S520R	520	Missense	central	0	yes	9.837	0.000	EPSD	COSMIC	5.915	Loss
CMGC_MAPK_p38_MAPK14_ST	Q14721	KCNB1	Q16539	MAPK14	S520	S518C	518	Missense	proximal	-2	no	9.837	8.702	EPSD	COSMIC	5.915	Down-regulation
CMGC_MAPK_p38_MAPK14_ST	Q14721	KCNB1	Q16539	MAPK14	S520	R516I	516	Missense	distal	-4	no	9.837	9.993	EPSD	COSMIC	5.915	Up-regulation
CMGC_MAPK_p38_MAPK14_ST	Q14721	KCNB1	Q16539	MAPK14	S607	P613S	613	Missense	distal	6	no	7.581	7.569	EPSD	COSMIC	5.915	Down-regulation
CMGC_MAPK_p38_MAPK14_ST	Q14721	KCNB1	Q16539	MAPK14	S607	S614R	614	Missense	distal	7	no	7.581	7.616	EPSD	COSMIC	5.915	Up-regulation
CMGC_MAPK_p38_MAPK14_ST	Q14721	KCNB1	Q16539	MAPK14	S607	H606N	606	Missense	proximal	-1	no	7.581	7.605	EPSD	COSMIC	5.915	Up-regulation
CMGC_MAPK_p38_MAPK14_ST	Q14721	KCNB1	Q16539	MAPK14	S656	S650F	650	Missense	distal	-6	no	9.831	8.067	EPSD	COSMIC	5.915	Down-regulation
CMGC_MAPK_p38_MAPK14_ST	Q14721	KCNB1	Q16539	MAPK14	S656	P657S	657	Missense	proximal	1	no	9.831	2.547	EPSD	COSMIC	5.915	Loss
CMGC_MAPK_p38_MAPK14_ST	Q14721	KCNB1	Q16539	MAPK14	S656	F652L	652	Missense	distal	-4	no	9.831	9.727	EPSD	COSMIC	5.915	Down-regulation
CMGC_MAPK_p38_MAPK14_ST	Q14721	KCNB1	Q16539	MAPK14	S720	D715N	715	Missense	distal	-5	no	11.321	11.162	EPSD	COSMIC	5.915	Down-regulation
CMGC_MAPK_p38_MAPK14_ST	Q14721	KCNB1	Q16539	MAPK14	S720	K716N	716	Missense	distal	-4	no	11.321	11.468	EPSD	COSMIC;CCLE	5.915	Up-regulation
CMGC_MAPK_p38_MAPK14_ST	Q14721	KCNB1	Q16539	MAPK14	S720	A717V	717	Missense	distal	-3	no	11.321	9.820	EPSD	COSMIC	5.915	Down-regulation
CMGC_MAPK_p38_MAPK14_ST	Q14721	KCNB1	Q16539	MAPK14	S783	P784L	784	Missense	proximal	1	no	12.078	4.027	EPSD	COSMIC	5.915	Loss
CMGC_MAPK_p38_MAPK14_ST	Q14721	KCNB1	Q16539	MAPK14	S783	T788K	788	Missense	distal	5	no	12.078	11.639	EPSD	COSMIC	5.915	Down-regulation
CMGC_MAPK_p38_MAPK14_ST	Q14721	KCNB1	Q16539	MAPK14	S783	G789R	789	Missense	distal	6	no	12.078	11.956	EPSD	COSMIC	5.915	Down-regulation
CMGC_MAPK_p38_MAPK14_ST	Q14721	KCNB1	Q16539	MAPK14	S783	G789E	789	Missense	distal	6	no	12.078	12.037	EPSD	COSMIC;GDSC;CCLE	5.915	Down-regulation
CMGC_MAPK_p38_MAPK14_ST	Q14721	KCNB1	Q16539	MAPK14	S800	N795S	795	Missense	distal	-5	no	11.299	10.835	PhosphoSitePlus;EPSD	COSMIC	5.915	Down-regulation
CMGC_MAPK_p38_MAPK14_ST	Q14721	KCNB1	Q16539	MAPK14	S800	K807N	807	Missense	distal	7	no	11.299	11.489	PhosphoSitePlus;EPSD	COSMIC	5.915	Up-regulation
CMGC_MAPK_p38_MAPK14_ST	Q14721	KCNB1	Q16539	MAPK14	S805	S800T	800	Missense	distal	-5	no	12.550	12.991	EPSD;PhosphoSitePlus	COSMIC	5.915	Up-regulation
CMGC_MAPK_p38_MAPK14_ST	Q14721	KCNB1	Q16539	MAPK14	S805	K807N	807	Missense	proximal	2	no	12.550	12.643	EPSD;PhosphoSitePlus	COSMIC	5.915	Up-regulation
CMGC_MAPK_p38_MAPK14_ST	P28324	ELK4	Q16539	MAPK14	S230	T227I	227	Missense	distal	-3	no	10.160	8.406	EPSD	COSMIC;GDSC;CCLE	5.915	Down-regulation
CMGC_MAPK_p38_MAPK14_ST	P28324	ELK4	Q16539	MAPK14	S230	Q223K	223	Missense	distal	-7	no	10.160	10.519	EPSD	COSMIC	5.915	Up-regulation
CMGC_MAPK_p38_MAPK14_ST	P28324	ELK4	Q16539	MAPK14	S230	S230F	230	Missense	central	0	yes	10.160	0.000	EPSD	COSMIC	5.915	Loss
CMGC_MAPK_p38_MAPK14_ST	P28324	ELK4	Q16539	MAPK14	S381	P382H	382	Missense	proximal	1	no	8.221	-5.433	EPSD;PhosphoSitePlus	COSMIC	5.915	Loss
CMGC_MAPK_p38_MAPK14_ST	P28324	ELK4	Q16539	MAPK14	S381	L380V	380	Missense	proximal	-1	no	8.221	8.159	EPSD;PhosphoSitePlus	COSMIC	5.915	Down-regulation
CMGC_MAPK_p38_MAPK14_ST	P28324	ELK4	Q16539	MAPK14	S387	P382H	382	Missense	distal	-5	no	12.952	13.266	PhosphoSitePlus;EPSD	COSMIC	5.915	Up-regulation
CMGC_MAPK_p38_MAPK14_ST	P28324	ELK4	Q16539	MAPK14	S387	L380V	380	Missense	distal	-7	no	12.952	12.528	PhosphoSitePlus;EPSD	COSMIC	5.915	Down-regulation
CMGC_MAPK_p38_MAPK14_ST	P28324	ELK4	Q16539	MAPK14	T420	D427N	427	Missense	distal	7	no	13.640	13.318	EPSD	COSMIC	5.915	Down-regulation
CMGC_MAPK_p38_MAPK14_ST	P28324	ELK4	Q16539	MAPK14	T420	F424L	424	Missense	distal	4	no	13.640	14.136	EPSD	COSMIC	5.915	Up-regulation
CMGC_MAPK_p38_MAPK14_ST	P28324	ELK4	Q16539	MAPK14	T420	G414W	414	Missense	distal	-6	no	13.640	12.697	EPSD	COSMIC	5.915	Down-regulation
CMGC_MAPK_p38_MAPK14_ST	P28324	ELK4	Q16539	MAPK14	T420	P421F	421	Missense	proximal	1	no	13.640	7.636	EPSD	COSMIC	5.915	Down-regulation
CMGC_MAPK_p38_MAPK14_ST	P28324	ELK4	Q16539	MAPK14	S425	K430N	430	Missense	distal	5	no	14.401	14.670	EPSD	COSMIC	5.915	Up-regulation
CMGC_MAPK_p38_MAPK14_ST	P28324	ELK4	Q16539	MAPK14	S425	D427N	427	Missense	proximal	2	no	14.401	14.631	EPSD	COSMIC	5.915	Up-regulation
CMGC_MAPK_p38_MAPK14_ST	P28324	ELK4	Q16539	MAPK14	S425	F424L	424	Missense	proximal	-1	no	14.401	14.437	EPSD	COSMIC	5.915	Up-regulation
CMGC_MAPK_p38_MAPK14_ST	P28324	ELK4	Q16539	MAPK14	S425	L428P	428	Missense	distal	3	no	14.401	14.367	EPSD	COSMIC	5.915	Down-regulation
CMGC_MAPK_p38_MAPK14_ST	P28324	ELK4	Q16539	MAPK14	S425	P421F	421	Missense	distal	-4	no	14.401	15.018	EPSD	COSMIC	5.915	Up-regulation
CMGC_MAPK_p38_MAPK14_ST	P04792	HSPB1	Q16539	MAPK14	S43	S49G	49	Missense	distal	6	no	8.128	8.249	EPSD	COSMIC;CCLE	5.915	Up-regulation
CMGC_MAPK_p38_MAPK14_ST	P04792	HSPB1	Q16539	MAPK14	S43	S43L	43	Missense	central	0	yes	8.128	0.000	EPSD	COSMIC	5.915	Loss
CMGC_MAPK_p38_MAPK14_ST	P04792	HSPB1	Q16539	MAPK14	S50	S49G	49	Missense	proximal	-1	no	6.745	6.958	EPSD	COSMIC;CCLE	5.915	Up-regulation
CMGC_MAPK_p38_MAPK14_ST	P04792	HSPB1	Q16539	MAPK14	S50	S43L	43	Missense	distal	-7	no	6.745	6.465	EPSD	COSMIC	5.915	Down-regulation
CMGC_MAPK_p38_MAPK14_ST	P04792	HSPB1	Q16539	MAPK14	S82	R75C	75	Missense	distal	-7	no	7.365	6.973	EPSD	COSMIC	5.915	Down-regulation
CMGC_MAPK_p38_MAPK14_ST	P04792	HSPB1	Q16539	MAPK14	S158	S154F	154	Missense	distal	-4	no	14.484	15.188	EPSD	COSMIC;GDSC;CCLE	5.915	Up-regulation
CMGC_MAPK_p38_MAPK14_ST	P04792	HSPB1	Q16539	MAPK14	S158	T151A	151	Missense	distal	-7	no	14.484	14.666	EPSD	COSMIC;GDSC;CCLE	5.915	Up-regulation
CMGC_MAPK_p38_MAPK14_ST	P03372	ESR1	Q16539	MAPK14	S104	F97L	97	Missense	distal	-7	no	7.848	8.314	EPSD	COSMIC	5.915	Up-regulation
CMGC_MAPK_p38_MAPK14_ST	P03372	ESR1	Q16539	MAPK14	S104	M109T	109	Missense	distal	5	no	7.848	8.161	EPSD	COSMIC	5.915	Up-regulation
CMGC_MAPK_p38_MAPK14_ST	P03372	ESR1	Q16539	MAPK14	S118	P113L	113	Missense	distal	-5	no	10.058	10.340	PhosphoSitePlus;EPSD	COSMIC	5.915	Up-regulation
CMGC_MAPK_p38_MAPK14_ST	P03372	ESR1	Q16539	MAPK14	S118	P113Q	113	Missense	distal	-5	no	10.058	9.787	PhosphoSitePlus;EPSD	COSMIC	5.915	Down-regulation
CMGC_MAPK_p38_MAPK14_ST	P03372	ESR1	Q16539	MAPK14	S118	L117Q	117	Missense	proximal	-1	no	10.058	9.761	PhosphoSitePlus;EPSD	COSMIC	5.915	Down-regulation
CMGC_MAPK_p38_MAPK14_ST	P03372	ESR1	Q16539	MAPK14	S118	H112L	112	Missense	distal	-6	no	10.058	9.908	PhosphoSitePlus;EPSD	COSMIC	5.915	Down-regulation
CMGC_MAPK_p38_MAPK14_ST	P03372	ESR1	Q16539	MAPK14	S118	S118P	118	Missense	central	0	yes	10.058	0.000	PhosphoSitePlus;EPSD	COSMIC	5.915	Loss
CMGC_MAPK_p38_MAPK14_ST	P03372	ESR1	Q16539	MAPK14	S282	G276S	276	Missense	distal	-6	no	5.641	6.122	EPSD	COSMIC	5.915	Gain
CMGC_MAPK_p38_MAPK14_ST	P03372	ESR1	Q16539	MAPK14	S294	K299R	299	Missense	distal	5	no	9.793	10.088	EPSD;PhosphoSitePlus	COSMIC	5.915	Up-regulation
CMGC_MAPK_p38_MAPK14_ST	P03372	ESR1	Q16539	MAPK14	S294	P295L	295	Missense	proximal	1	no	9.793	1.743	EPSD;PhosphoSitePlus	COSMIC	5.915	Loss
CMGC_MAPK_p38_MAPK14_ST	P03372	ESR1	Q16539	MAPK14	S294	R300C	300	Missense	distal	6	no	9.793	9.519	EPSD;PhosphoSitePlus	COSMIC;CCLE	5.915	Down-regulation
CMGC_MAPK_p38_MAPK14_ST	P03372	ESR1	Q16539	MAPK14	S294	L296P	296	Missense	proximal	2	no	9.793	9.906	EPSD;PhosphoSitePlus	COSMIC	5.915	Up-regulation
CMGC_MAPK_p38_MAPK14_ST	P03372	ESR1	Q16539	MAPK14	S294	N290K	290	Missense	distal	-4	no	9.793	9.647	EPSD;PhosphoSitePlus	COSMIC	5.915	Down-regulation
CMGC_MAPK_p38_MAPK14_ST	P03372	ESR1	Q16539	MAPK14	S294	S294R	294	Missense	central	0	yes	9.793	0.000	EPSD;PhosphoSitePlus	COSMIC	5.915	Loss
CMGC_MAPK_p38_MAPK14_ST	P03372	ESR1	Q16539	MAPK14	S294	A288T	288	Missense	distal	-6	no	9.793	10.063	EPSD;PhosphoSitePlus	COSMIC	5.915	Up-regulation
CMGC_MAPK_p38_MAPK14_ST	P03372	ESR1	Q16539	MAPK14	S294	R287H	287	Missense	distal	-7	no	9.793	9.499	EPSD;PhosphoSitePlus	COSMIC	5.915	Down-regulation
CMGC_MAPK_p38_MAPK14_ST	P03372	ESR1	Q16539	MAPK14	S294	R287C	287	Missense	distal	-7	no	9.793	9.401	EPSD;PhosphoSitePlus	COSMIC	5.915	Down-regulation
CMGC_MAPK_p38_MAPK14_ST	P03372	ESR1	Q16539	MAPK14	S341	S338G	338	Missense	distal	-3	no	6.264	5.327	EPSD	COSMIC	5.915	Loss
CMGC_MAPK_p38_MAPK14_ST	P03372	ESR1	Q16539	MAPK14	S341	S338R	338	Missense	distal	-3	no	6.264	6.777	EPSD	COSMIC	5.915	Up-regulation
CMGC_MAPK_p38_MAPK14_ST	P03372	ESR1	Q16539	MAPK14	S341	T347I	347	Missense	distal	6	no	6.264	6.016	EPSD	COSMIC	5.915	Down-regulation
CMGC_MAPK_p38_MAPK14_ST	P03372	ESR1	Q16539	MAPK14	S341	M343L	343	Missense	proximal	2	no	6.264	6.029	EPSD	COSMIC	5.915	Down-regulation
CMGC_MAPK_p38_MAPK14_ST	P03372	ESR1	Q16539	MAPK14	S554	G557R	557	Missense	distal	3	no	6.644	6.630	EPSD	COSMIC	5.915	Down-regulation
CMGC_MAPK_p38_MAPK14_ST	P03372	ESR1	Q16539	MAPK14	S554	H550Y	550	Missense	distal	-4	no	6.644	6.418	EPSD	COSMIC	5.915	Down-regulation
CMGC_MAPK_p38_MAPK14_ST	P03372	ESR1	Q16539	MAPK14	S554	L549P	549	Missense	distal	-5	no	6.644	6.363	EPSD	COSMIC	5.915	Down-regulation
CMGC_MAPK_p38_MAPK14_ST	P03372	ESR1	Q16539	MAPK14	S554	V560M	560	Missense	distal	6	no	6.644	6.933	EPSD	COSMIC	5.915	Up-regulation
CMGC_MAPK_p38_MAPK14_ST	Q9H3D4	TP63	Q16539	MAPK14	S30	E24K	24	Missense	distal	-6	no	6.858	6.443	EPSD	COSMIC	5.915	Down-regulation
CMGC_MAPK_p38_MAPK14_ST	Q9H3D4	TP63	Q16539	MAPK14	S30	P26A	26	Missense	distal	-4	no	6.858	6.811	EPSD	COSMIC	5.915	Down-regulation
CMGC_MAPK_p38_MAPK14_ST	Q9H3D4	TP63	Q16539	MAPK14	S30	H28D	28	Missense	proximal	-2	no	6.858	7.435	EPSD	COSMIC	5.915	Up-regulation
CMGC_MAPK_p38_MAPK14_ST	Q9H3D4	TP63	Q16539	MAPK14	S30	Y35F	35	Missense	distal	5	no	6.858	5.696	EPSD	COSMIC	5.915	Loss
CMGC_MAPK_p38_MAPK14_ST	Q9H3D4	TP63	Q16539	MAPK14	S30	S34A	34	Missense	distal	4	no	6.858	6.552	EPSD	COSMIC	5.915	Down-regulation
CMGC_MAPK_p38_MAPK14_ST	Q9H3D4	TP63	Q16539	MAPK14	S30	S34F	34	Missense	distal	4	no	6.858	5.284	EPSD	COSMIC	5.915	Loss
CMGC_MAPK_p38_MAPK14_ST	Q9H3D4	TP63	Q16539	MAPK14	S30	A27T	27	Missense	distal	-3	no	6.858	6.952	EPSD	COSMIC	5.915	Up-regulation
CMGC_MAPK_p38_MAPK14_ST	Q9H3D4	TP63	Q16539	MAPK14	T46	T39A	39	Missense	distal	-7	no	5.903	6.086	EPSD	COSMIC	5.915	Gain
CMGC_MAPK_p38_MAPK14_ST	Q9H3D4	TP63	Q16539	MAPK14	T46	S41F	41	Missense	distal	-5	no	5.903	6.688	EPSD	COSMIC	5.915	Gain
CMGC_MAPK_p38_MAPK14_ST	Q9H3D4	TP63	Q16539	MAPK14	S51	E48K	48	Missense	distal	-3	no	10.525	10.133	EPSD	COSMIC	5.915	Down-regulation
CMGC_MAPK_p38_MAPK14_ST	Q9H3D4	TP63	Q16539	MAPK14	S51	S51N	51	Missense	central	0	yes	10.525	0.000	EPSD	COSMIC	5.915	Loss
CMGC_MAPK_p38_MAPK14_ST	Q9H3D4	TP63	Q16539	MAPK14	S51	F55V	55	Missense	distal	4	no	10.525	11.360	EPSD	COSMIC	5.915	Up-regulation
CMGC_MAPK_p38_MAPK14_ST	Q9H3D4	TP63	Q16539	MAPK14	S51	F55L	55	Missense	distal	4	no	10.525	11.021	EPSD	COSMIC	5.915	Up-regulation
CMGC_MAPK_p38_MAPK14_ST	Q9H3D4	TP63	Q16539	MAPK14	S51	L50F	50	Missense	proximal	-1	no	10.525	10.489	EPSD	COSMIC	5.915	Down-regulation
CMGC_MAPK_p38_MAPK14_ST	Q9H3D4	TP63	Q16539	MAPK14	S51	P52L	52	Missense	proximal	1	no	10.525	2.474	EPSD	COSMIC	5.915	Loss
CMGC_MAPK_p38_MAPK14_ST	Q9H3D4	TP63	Q16539	MAPK14	S51	H57R	57	Missense	distal	6	no	10.525	10.632	EPSD	COSMIC	5.915	Up-regulation
CMGC_MAPK_p38_MAPK14_ST	Q9H3D4	TP63	Q16539	MAPK14	S160	P161S	161	Missense	proximal	1	no	12.600	5.316	EPSD	COSMIC	5.915	Loss
CMGC_MAPK_p38_MAPK14_ST	Q9H3D4	TP63	Q16539	MAPK14	S160	L159F	159	Missense	proximal	-1	no	12.600	12.564	EPSD	COSMIC	5.915	Down-regulation
CMGC_MAPK_p38_MAPK14_ST	Q9H3D4	TP63	Q16539	MAPK14	S160	S160C	160	Missense	central	0	yes	12.600	0.000	EPSD	COSMIC	5.915	Loss
CMGC_MAPK_p38_MAPK14_ST	Q9H3D4	TP63	Q16539	MAPK14	S160	S154C	154	Missense	distal	-6	no	12.600	11.307	EPSD	COSMIC;CCLE	5.915	Down-regulation
CMGC_MAPK_p38_MAPK14_ST	Q9H3D4	TP63	Q16539	MAPK14	S160	S153I	153	Missense	distal	-7	no	12.600	12.179	EPSD	COSMIC	5.915	Down-regulation
CMGC_MAPK_p38_MAPK14_ST	Q9H3D4	TP63	Q16539	MAPK14	S160	P166H	166	Missense	distal	6	no	12.600	12.480	EPSD	COSMIC	5.915	Down-regulation
CMGC_MAPK_p38_MAPK14_ST	Q9H3D4	TP63	Q16539	MAPK14	S160	P161L	161	Missense	proximal	1	no	12.600	4.549	EPSD	COSMIC	5.915	Loss
CMGC_MAPK_p38_MAPK14_ST	Q9H3D4	TP63	Q16539	MAPK14	S162	T169N	169	Missense	distal	7	no	9.524	9.547	EPSD	COSMIC	5.915	Up-regulation
CMGC_MAPK_p38_MAPK14_ST	Q9H3D4	TP63	Q16539	MAPK14	S162	P161S	161	Missense	proximal	-1	no	9.524	9.432	EPSD	COSMIC	5.915	Down-regulation
CMGC_MAPK_p38_MAPK14_ST	Q9H3D4	TP63	Q16539	MAPK14	S162	L159F	159	Missense	distal	-3	no	9.524	8.548	EPSD	COSMIC	5.915	Down-regulation
CMGC_MAPK_p38_MAPK14_ST	Q9H3D4	TP63	Q16539	MAPK14	S162	S160C	160	Missense	proximal	-2	no	9.524	8.389	EPSD	COSMIC	5.915	Down-regulation
CMGC_MAPK_p38_MAPK14_ST	Q9H3D4	TP63	Q16539	MAPK14	S162	T169I	169	Missense	distal	7	no	9.524	9.113	EPSD	COSMIC	5.915	Down-regulation
CMGC_MAPK_p38_MAPK14_ST	Q9H3D4	TP63	Q16539	MAPK14	S162	P166H	166	Missense	distal	4	no	9.524	8.854	EPSD	COSMIC	5.915	Down-regulation
CMGC_MAPK_p38_MAPK14_ST	Q9H3D4	TP63	Q16539	MAPK14	S162	N168S	168	Missense	distal	6	no	9.524	9.545	EPSD	COSMIC	5.915	Up-regulation
CMGC_MAPK_p38_MAPK14_ST	Q9H3D4	TP63	Q16539	MAPK14	S162	P161L	161	Missense	proximal	-1	no	9.524	9.710	EPSD	COSMIC	5.915	Up-regulation
CMGC_MAPK_p38_MAPK14_ST	Q9H3D4	TP63	Q16539	MAPK14	S395	K392E	392	Missense	distal	-3	no	13.209	13.602	EPSD	COSMIC	5.915	Up-regulation
CMGC_MAPK_p38_MAPK14_ST	Q9H3D4	TP63	Q16539	MAPK14	S395	S395F	395	Missense	central	0	yes	13.209	0.000	EPSD	COSMIC;GDSC	5.915	Loss
CMGC_MAPK_p38_MAPK14_ST	Q9H3D4	TP63	Q16539	MAPK14	S455	S462L	462	Missense	distal	7	no	10.132	9.747	EPSD	COSMIC	5.915	Down-regulation
CMGC_MAPK_p38_MAPK14_ST	Q9H3D4	TP63	Q16539	MAPK14	S455	S462A	462	Missense	distal	7	no	10.132	10.154	EPSD	COSMIC	5.915	Up-regulation
CMGC_MAPK_p38_MAPK14_ST	Q9H3D4	TP63	Q16539	MAPK14	S455	Q454H	454	Missense	proximal	-1	no	10.132	10.198	EPSD	COSMIC	5.915	Up-regulation
CMGC_MAPK_p38_MAPK14_ST	Q9H3D4	TP63	Q16539	MAPK14	S455	Q454R	454	Missense	proximal	-1	no	10.132	10.043	EPSD	COSMIC	5.915	Down-regulation
CMGC_MAPK_p38_MAPK14_ST	Q9H3D4	TP63	Q16539	MAPK14	S455	Q450R	450	Missense	distal	-5	no	10.132	10.174	EPSD	COSMIC	5.915	Up-regulation
CMGC_MAPK_p38_MAPK14_ST	Q9H3D4	TP63	Q16539	MAPK14	S455	Q450H	450	Missense	distal	-5	no	10.132	10.717	EPSD	COSMIC	5.915	Up-regulation
CMGC_MAPK_p38_MAPK14_ST	Q9H3D4	TP63	Q16539	MAPK14	S455	S457G	457	Missense	proximal	2	no	10.132	9.903	EPSD	COSMIC	5.915	Down-regulation
CMGC_MAPK_p38_MAPK14_ST	Q9H3D4	TP63	Q16539	MAPK14	S457	Q454R	454	Missense	distal	-3	no	5.888	7.667	EPSD	COSMIC	5.915	Gain
CMGC_MAPK_p38_MAPK14_ST	Q9H3D4	TP63	Q16539	MAPK14	S457	Q450R	450	Missense	distal	-7	no	5.888	5.981	EPSD	COSMIC	5.915	Gain
CMGC_MAPK_p38_MAPK14_ST	Q9H3D4	TP63	Q16539	MAPK14	S463	S462L	462	Missense	proximal	-1	no	11.330	11.609	EPSD	COSMIC	5.915	Up-regulation
CMGC_MAPK_p38_MAPK14_ST	Q9H3D4	TP63	Q16539	MAPK14	S463	S462A	462	Missense	proximal	-1	no	11.330	11.390	EPSD	COSMIC	5.915	Up-regulation
CMGC_MAPK_p38_MAPK14_ST	Q9H3D4	TP63	Q16539	MAPK14	S463	N467K	467	Missense	distal	4	no	11.330	11.881	EPSD	COSMIC	5.915	Up-regulation
CMGC_MAPK_p38_MAPK14_ST	Q9H3D4	TP63	Q16539	MAPK14	S463	N470S	470	Missense	distal	7	no	11.330	11.629	EPSD	COSMIC;GDSC;CCLE	5.915	Up-regulation
CMGC_MAPK_p38_MAPK14_ST	Q9H3D4	TP63	Q16539	MAPK14	S463	S457G	457	Missense	distal	-6	no	11.330	10.850	EPSD	COSMIC	5.915	Down-regulation
CMGC_MAPK_p38_MAPK14_ST	Q9H3D4	TP63	Q16539	MAPK14	T491	P492H	492	Missense	proximal	1	no	6.592	-7.061	EPSD	COSMIC	5.915	Loss
CMGC_MAPK_p38_MAPK14_ST	Q9H3D4	TP63	Q16539	MAPK14	T491	P484H	484	Missense	distal	-7	no	6.592	6.216	EPSD	COSMIC	5.915	Down-regulation
CMGC_MAPK_p38_MAPK14_ST	Q9H3D4	TP63	Q16539	MAPK14	T491	T494A	494	Missense	distal	3	no	6.592	6.593	EPSD	COSMIC	5.915	Up-regulation
CMGC_MAPK_p38_MAPK14_ST	Q9H3D4	TP63	Q16539	MAPK14	T491	I495M	495	Missense	distal	4	no	6.592	7.057	EPSD	COSMIC	5.915	Up-regulation
CMGC_MAPK_p38_MAPK14_ST	Q9H3D4	TP63	Q16539	MAPK14	T491	P492T	492	Missense	proximal	1	no	6.592	-0.861	EPSD	COSMIC	5.915	Loss
CMGC_MAPK_p38_MAPK14_ST	Q9H3D4	TP63	Q16539	MAPK14	T491	L490R	490	Missense	proximal	-1	no	6.592	6.207	EPSD	COSMIC	5.915	Down-regulation
CMGC_MAPK_p38_MAPK14_ST	Q9H3D4	TP63	Q16539	MAPK14	T491	P496H	496	Missense	distal	5	no	6.592	6.038	EPSD	COSMIC	5.915	Down-regulation
CMGC_MAPK_p38_MAPK14_ST	Q9H3D4	TP63	Q16539	MAPK14	S551	V550F	550	Missense	proximal	-1	no	6.075	6.101	EPSD	COSMIC	5.915	Up-regulation
CMGC_MAPK_p38_MAPK14_ST	Q9H3D4	TP63	Q16539	MAPK14	S551	S551G	551	Missense	central	0	yes	6.075	0.000	EPSD	COSMIC	5.915	Loss
CMGC_MAPK_p38_MAPK14_ST	Q9H3D4	TP63	Q16539	MAPK14	S551	A554E	554	Missense	distal	3	no	6.075	6.056	EPSD	COSMIC	5.915	Down-regulation
CMGC_MAPK_p38_MAPK14_ST	Q9H3D4	TP63	Q16539	MAPK14	S551	R555S	555	Missense	distal	4	no	6.075	6.792	EPSD	COSMIC	5.915	Up-regulation
CMGC_MAPK_p38_MAPK14_ST	Q9H3D4	TP63	Q16539	MAPK14	S612	R618W	618	Missense	distal	6	no	11.479	11.216	EPSD	COSMIC;GDSC;CCLE	5.915	Down-regulation
CMGC_MAPK_p38_MAPK14_ST	Q9H3D4	TP63	Q16539	MAPK14	S612	R605Q	605	Missense	distal	-7	no	11.479	11.385	EPSD	COSMIC;GDSC	5.915	Down-regulation
CMGC_MAPK_p38_MAPK14_ST	Q9H3D4	TP63	Q16539	MAPK14	S612	R618Q	618	Missense	distal	6	no	11.479	11.491	EPSD	COSMIC	5.915	Up-regulation
CMGC_MAPK_p38_MAPK14_ST	Q9H3D4	TP63	Q16539	MAPK14	S612	R605W	605	Missense	distal	-7	no	11.479	10.740	EPSD	COSMIC	5.915	Down-regulation
CMGC_MAPK_p38_MAPK14_ST	Q9H3D4	TP63	Q16539	MAPK14	S612	S612F	612	Missense	central	0	yes	11.479	0.000	EPSD	COSMIC	5.915	Loss
CMGC_MAPK_p38_MAPK14_ST	Q9H3D4	TP63	Q16539	MAPK14	S612	P613L	613	Missense	proximal	1	no	11.479	3.428	EPSD	COSMIC	5.915	Loss
CMGC_MAPK_p38_MAPK14_ST	Q9H3D4	TP63	Q16539	MAPK14	S612	H615D	615	Missense	distal	3	no	11.479	11.432	EPSD	COSMIC	5.915	Down-regulation
CMGC_MAPK_p38_MAPK14_ST	Q9H3D4	TP63	Q16539	MAPK14	S612	P613T	613	Missense	proximal	1	no	11.479	4.026	EPSD	COSMIC	5.915	Loss
CMGC_MAPK_p38_MAPK14_ST	Q9H3D4	TP63	Q16539	MAPK14	S612	H608Q	608	Missense	distal	-4	no	11.479	11.636	EPSD	COSMIC	5.915	Up-regulation
CMGC_MAPK_p38_MAPK14_ST	Q9H3D4	TP63	Q16539	MAPK14	S614	H615D	615	Missense	proximal	1	no	0.016	6.238	EPSD	COSMIC	5.915	Gain
CMGC_MAPK_p38_MAPK14_ST	Q9H3D4	TP63	Q16539	MAPK14	T619	V626F	626	Missense	distal	7	no	8.101	7.318	EPSD	COSMIC	5.915	Down-regulation
CMGC_MAPK_p38_MAPK14_ST	Q9H3D4	TP63	Q16539	MAPK14	T619	R618W	618	Missense	proximal	-1	no	8.101	8.389	EPSD	COSMIC;GDSC;CCLE	5.915	Up-regulation
CMGC_MAPK_p38_MAPK14_ST	Q9H3D4	TP63	Q16539	MAPK14	T619	R618Q	618	Missense	proximal	-1	no	8.101	8.190	EPSD	COSMIC	5.915	Up-regulation
CMGC_MAPK_p38_MAPK14_ST	Q9H3D4	TP63	Q16539	MAPK14	T619	S622I	622	Missense	distal	3	no	8.101	8.197	EPSD	COSMIC	5.915	Up-regulation
CMGC_MAPK_p38_MAPK14_ST	Q9H3D4	TP63	Q16539	MAPK14	T619	S612F	612	Missense	distal	-7	no	8.101	7.355	EPSD	COSMIC	5.915	Down-regulation
CMGC_MAPK_p38_MAPK14_ST	Q9H3D4	TP63	Q16539	MAPK14	T619	P613L	613	Missense	distal	-6	no	8.101	7.488	EPSD	COSMIC	5.915	Down-regulation
CMGC_MAPK_p38_MAPK14_ST	Q9H3D4	TP63	Q16539	MAPK14	T619	H615D	615	Missense	distal	-4	no	8.101	8.373	EPSD	COSMIC	5.915	Up-regulation
CMGC_MAPK_p38_MAPK14_ST	Q9H3D4	TP63	Q16539	MAPK14	T619	P613T	613	Missense	distal	-6	no	8.101	8.435	EPSD	COSMIC	5.915	Up-regulation
CMGC_MAPK_p38_MAPK14_ST	Q9H3D4	TP63	Q16539	MAPK14	S622	V626F	626	Missense	distal	4	no	6.872	6.037	EPSD	COSMIC	5.915	Down-regulation
CMGC_MAPK_p38_MAPK14_ST	Q9H3D4	TP63	Q16539	MAPK14	S622	R618W	618	Missense	distal	-4	no	6.872	7.501	EPSD	COSMIC;GDSC;CCLE	5.915	Up-regulation
CMGC_MAPK_p38_MAPK14_ST	Q9H3D4	TP63	Q16539	MAPK14	S622	G629D	629	Missense	distal	7	no	6.872	7.038	EPSD	COSMIC	5.915	Up-regulation
CMGC_MAPK_p38_MAPK14_ST	Q9H3D4	TP63	Q16539	MAPK14	S622	R618Q	618	Missense	distal	-4	no	6.872	7.240	EPSD	COSMIC	5.915	Up-regulation
CMGC_MAPK_p38_MAPK14_ST	Q9H3D4	TP63	Q16539	MAPK14	S622	S622I	622	Missense	central	0	yes	6.872	0.000	EPSD	COSMIC	5.915	Loss
CMGC_MAPK_p38_MAPK14_ST	Q9H3D4	TP63	Q16539	MAPK14	S622	G629R	629	Missense	distal	7	no	6.872	7.050	EPSD	COSMIC	5.915	Up-regulation
CMGC_MAPK_p38_MAPK14_ST	Q9H3D4	TP63	Q16539	MAPK14	S622	H615D	615	Missense	distal	-7	no	6.872	6.904	EPSD	COSMIC	5.915	Up-regulation
CMGC_MAPK_p38_MAPK14_ST	Q9H3D4	TP63	Q16539	MAPK14	S622	V628E	628	Missense	distal	6	no	6.872	7.192	EPSD	COSMIC	5.915	Up-regulation
CMGC_MAPK_p38_MAPK14_ST	Q9H3D4	TP63	Q16539	MAPK14	S622	V628M	628	Missense	distal	6	no	6.872	7.161	EPSD	COSMIC	5.915	Up-regulation
CMGC_MAPK_p38_MAPK14_ST	Q9H3D4	TP63	Q16539	MAPK14	S622	V628A	628	Missense	distal	6	no	6.872	7.167	EPSD	COSMIC	5.915	Up-regulation
CMGC_MAPK_p38_MAPK14_ST	Q9H3D4	TP63	Q16539	MAPK14	T625	V626F	626	Missense	proximal	1	no	3.882	7.157	EPSD	COSMIC	5.915	Gain
CMGC_MAPK_p38_MAPK14_ST	Q9H3D4	TP63	Q16539	MAPK14	S627	V628M	628	Missense	proximal	1	no	3.849	5.963	EPSD	COSMIC	5.915	Gain
CMGC_MAPK_p38_MAPK14_ST	Q9H3D4	TP63	Q16539	MAPK14	S627	V628A	628	Missense	proximal	1	no	3.849	6.808	EPSD	COSMIC	5.915	Gain
CMGC_MAPK_p38_MAPK14_ST	P29353	SHC1	Q16539	MAPK14	T29	S28A	28	Missense	proximal	-1	no	11.108	11.168	EPSD	COSMIC	5.915	Up-regulation
CMGC_MAPK_p38_MAPK14_ST	P29353	SHC1	Q16539	MAPK14	S54	D52E	52	Missense	proximal	-2	no	9.645	11.073	PhosphoSitePlus;EPSD	COSMIC	5.915	Up-regulation
CMGC_MAPK_p38_MAPK14_ST	P29353	SHC1	Q16539	MAPK14	S80	A74P	74	Missense	distal	-6	no	6.165	6.100	EPSD	COSMIC	5.915	Down-regulation
CMGC_MAPK_p38_MAPK14_ST	P29353	SHC1	Q16539	MAPK14	S80	G75R	75	Missense	distal	-5	no	6.165	6.002	EPSD	COSMIC	5.915	Down-regulation
CMGC_MAPK_p38_MAPK14_ST	P29353	SHC1	Q16539	MAPK14	S139	T135P	135	Missense	distal	-4	no	8.842	8.652	EPSD	COSMIC;GDSC	5.915	Down-regulation
CMGC_MAPK_p38_MAPK14_ST	P29353	SHC1	Q16539	MAPK14	S139	R146W	146	Missense	distal	7	no	8.842	8.153	EPSD	COSMIC	5.915	Down-regulation
CMGC_MAPK_p38_MAPK14_ST	P29353	SHC1	Q16539	MAPK14	T145	R146W	146	Missense	proximal	1	no	4.711	6.677	EPSD	COSMIC	5.915	Gain
CMGC_MAPK_p38_MAPK14_ST	P29353	SHC1	Q16539	MAPK14	T324	N318K	318	Missense	distal	-6	no	11.514	11.352	EPSD	COSMIC	5.915	Down-regulation
CMGC_MAPK_p38_MAPK14_ST	P29353	SHC1	Q16539	MAPK14	T324	V323L	323	Missense	proximal	-1	no	11.514	11.576	EPSD	COSMIC	5.915	Up-regulation
CMGC_MAPK_p38_MAPK14_ST	P29353	SHC1	Q16539	MAPK14	T324	D327H	327	Missense	distal	3	no	11.514	11.561	EPSD	COSMIC	5.915	Up-regulation
CMGC_MAPK_p38_MAPK14_ST	P29353	SHC1	Q16539	MAPK14	T324	R328W	328	Missense	distal	4	no	11.514	10.239	EPSD	COSMIC	5.915	Down-regulation
CMGC_MAPK_p38_MAPK14_ST	P29353	SHC1	Q16539	MAPK14	T324	R328Q	328	Missense	distal	4	no	11.514	11.309	EPSD	COSMIC	5.915	Down-regulation
CMGC_MAPK_p38_MAPK14_ST	P29353	SHC1	Q16539	MAPK14	T386	A392D	392	Missense	distal	6	no	9.374	9.299	EPSD;PhosphoSitePlus	COSMIC	5.915	Down-regulation
CMGC_MAPK_p38_MAPK14_ST	P29353	SHC1	Q16539	MAPK14	T386	A381V	381	Missense	distal	-5	no	9.374	9.866	EPSD;PhosphoSitePlus	COSMIC;GDSC;CCLE	5.915	Up-regulation
CMGC_MAPK_p38_MAPK14_ST	P29353	SHC1	Q16539	MAPK14	T386	L390F	390	Missense	distal	4	no	9.374	8.879	EPSD;PhosphoSitePlus	COSMIC	5.915	Down-regulation
CMGC_MAPK_p38_MAPK14_ST	P29353	SHC1	Q16539	MAPK14	T516	R511W	511	Missense	distal	-5	no	9.436	10.181	EPSD	COSMIC	5.915	Up-regulation
CMGC_MAPK_p38_MAPK14_ST	Q86UR1	NOXA1	Q16539	MAPK14	S239	R241I	241	Missense	proximal	2	no	10.653	10.319	PhosphoSitePlus;EPSD	COSMIC	5.915	Down-regulation
CMGC_MAPK_p38_MAPK14_ST	Q86UR1	NOXA1	Q16539	MAPK14	S239	P240Q	240	Missense	proximal	1	no	10.653	3.444	PhosphoSitePlus;EPSD	COSMIC	5.915	Loss
CMGC_MAPK_p38_MAPK14_ST	Q86UR1	NOXA1	Q16539	MAPK14	S239	S234P	234	Missense	distal	-5	no	10.653	11.101	PhosphoSitePlus;EPSD	COSMIC	5.915	Up-regulation
CMGC_MAPK_p38_MAPK14_ST	Q86UR1	NOXA1	Q16539	MAPK14	S239	H245Y	245	Missense	distal	6	no	10.653	10.779	PhosphoSitePlus;EPSD	COSMIC	5.915	Up-regulation
CMGC_MAPK_p38_MAPK14_ST	Q86UR1	NOXA1	Q16539	MAPK14	S239	S239P	239	Missense	central	0	yes	10.653	0.000	PhosphoSitePlus;EPSD	COSMIC	5.915	Loss
CMGC_MAPK_p38_MAPK14_ST	Q86UR1	NOXA1	Q16539	MAPK14	S282	P286L	286	Missense	distal	4	no	10.991	10.352	EPSD;PhosphoSitePlus	COSMIC	5.915	Down-regulation
CMGC_MAPK_p38_MAPK14_ST	P41212	ETV6	Q16539	MAPK14	T4	C8Y	8	Missense	distal	4	no	9.364	9.468	EPSD	COSMIC	5.915	Up-regulation
CMGC_MAPK_p38_MAPK14_ST	P41212	ETV6	Q16539	MAPK14	T4	S2C	2	Missense	proximal	-2	no	9.364	8.229	EPSD	COSMIC	5.915	Down-regulation
CMGC_MAPK_p38_MAPK14_ST	P41212	ETV6	Q16539	MAPK14	T4	T4I	4	Missense	central	0	yes	9.364	0.000	EPSD	COSMIC	5.915	Loss
CMGC_MAPK_p38_MAPK14_ST	P41212	ETV6	Q16539	MAPK14	T18	P25R	25	Missense	distal	7	no	6.916	7.172	EPSD	COSMIC	5.915	Up-regulation
CMGC_MAPK_p38_MAPK14_ST	P41212	ETV6	Q16539	MAPK14	T18	P23Q	23	Missense	distal	5	no	6.916	6.707	EPSD	COSMIC	5.915	Down-regulation
CMGC_MAPK_p38_MAPK14_ST	P41212	ETV6	Q16539	MAPK14	T18	S22R	22	Missense	distal	4	no	6.916	6.199	EPSD	COSMIC	5.915	Down-regulation
CMGC_MAPK_p38_MAPK14_ST	P41212	ETV6	Q16539	MAPK14	S22	A28P	28	Missense	distal	6	no	12.051	12.008	EPSD;PhosphoSitePlus	COSMIC	5.915	Down-regulation
CMGC_MAPK_p38_MAPK14_ST	P41212	ETV6	Q16539	MAPK14	S22	P25R	25	Missense	distal	3	no	12.051	12.039	EPSD;PhosphoSitePlus	COSMIC	5.915	Down-regulation
CMGC_MAPK_p38_MAPK14_ST	P41212	ETV6	Q16539	MAPK14	S22	P23Q	23	Missense	proximal	1	no	12.051	4.843	EPSD;PhosphoSitePlus	COSMIC	5.915	Loss
CMGC_MAPK_p38_MAPK14_ST	P41212	ETV6	Q16539	MAPK14	S22	A28V	28	Missense	distal	6	no	12.051	11.756	EPSD;PhosphoSitePlus	COSMIC	5.915	Down-regulation
CMGC_MAPK_p38_MAPK14_ST	P41212	ETV6	Q16539	MAPK14	S22	S22R	22	Missense	central	0	yes	12.051	0.000	EPSD;PhosphoSitePlus	COSMIC	5.915	Loss
CMGC_MAPK_p38_MAPK14_ST	P41212	ETV6	Q16539	MAPK14	S22	S29F	29	Missense	distal	7	no	12.051	11.181	EPSD;PhosphoSitePlus	COSMIC	5.915	Down-regulation
CMGC_MAPK_p38_MAPK14_ST	P41212	ETV6	Q16539	MAPK14	T31	A28P	28	Missense	distal	-3	no	8.234	7.882	EPSD	COSMIC	5.915	Down-regulation
CMGC_MAPK_p38_MAPK14_ST	P41212	ETV6	Q16539	MAPK14	T31	P25R	25	Missense	distal	-6	no	8.234	8.735	EPSD	COSMIC	5.915	Up-regulation
CMGC_MAPK_p38_MAPK14_ST	P41212	ETV6	Q16539	MAPK14	T31	A28V	28	Missense	distal	-3	no	8.234	6.733	EPSD	COSMIC	5.915	Down-regulation
CMGC_MAPK_p38_MAPK14_ST	P41212	ETV6	Q16539	MAPK14	T31	P36L	36	Missense	distal	5	no	8.234	7.737	EPSD	COSMIC	5.915	Down-regulation
CMGC_MAPK_p38_MAPK14_ST	P41212	ETV6	Q16539	MAPK14	T31	P38L	38	Missense	distal	7	no	8.234	8.071	EPSD	COSMIC	5.915	Down-regulation
CMGC_MAPK_p38_MAPK14_ST	P41212	ETV6	Q16539	MAPK14	T31	S29F	29	Missense	proximal	-2	no	8.234	7.510	EPSD	COSMIC	5.915	Down-regulation
CMGC_MAPK_p38_MAPK14_ST	P41212	ETV6	Q16539	MAPK14	S131	G137V	137	Missense	distal	6	no	10.736	10.375	EPSD	COSMIC	5.915	Down-regulation
CMGC_MAPK_p38_MAPK14_ST	P41212	ETV6	Q16539	MAPK14	S131	P132S	132	Missense	proximal	1	no	10.736	3.453	EPSD	COSMIC	5.915	Loss
CMGC_MAPK_p38_MAPK14_ST	P41212	ETV6	Q16539	MAPK14	S131	P136S	136	Missense	distal	5	no	10.736	11.187	EPSD	COSMIC	5.915	Up-regulation
CMGC_MAPK_p38_MAPK14_ST	P41212	ETV6	Q16539	MAPK14	T161	N156S	156	Missense	distal	-5	no	8.711	8.248	EPSD	COSMIC	5.915	Down-regulation
CMGC_MAPK_p38_MAPK14_ST	P41212	ETV6	Q16539	MAPK14	T161	D155Y	155	Missense	distal	-6	no	8.711	8.694	EPSD	COSMIC	5.915	Down-regulation
CMGC_MAPK_p38_MAPK14_ST	P41212	ETV6	Q16539	MAPK14	T161	Q159R	159	Missense	proximal	-2	no	8.711	9.038	EPSD	COSMIC	5.915	Up-regulation
CMGC_MAPK_p38_MAPK14_ST	P41212	ETV6	Q16539	MAPK14	T161	P162S	162	Missense	proximal	1	no	8.711	1.427	EPSD	COSMIC	5.915	Loss
CMGC_MAPK_p38_MAPK14_ST	P41212	ETV6	Q16539	MAPK14	T161	S165C	165	Missense	distal	4	no	8.711	7.560	EPSD	COSMIC	5.915	Down-regulation
CMGC_MAPK_p38_MAPK14_ST	P41212	ETV6	Q16539	MAPK14	T161	V166M	166	Missense	distal	5	no	8.711	8.889	EPSD	COSMIC	5.915	Up-regulation
CMGC_MAPK_p38_MAPK14_ST	P41212	ETV6	Q16539	MAPK14	T161	D167H	167	Missense	distal	6	no	8.711	8.624	EPSD	COSMIC	5.915	Down-regulation
CMGC_MAPK_p38_MAPK14_ST	P41212	ETV6	Q16539	MAPK14	S184	E177Q	177	Missense	distal	-7	no	12.096	11.683	EPSD	COSMIC	5.915	Down-regulation
CMGC_MAPK_p38_MAPK14_ST	P41212	ETV6	Q16539	MAPK14	S184	I186V	186	Missense	proximal	2	no	12.096	12.148	EPSD	COSMIC	5.915	Up-regulation
CMGC_MAPK_p38_MAPK14_ST	P41212	ETV6	Q16539	MAPK14	S184	R191W	191	Missense	distal	7	no	12.096	11.408	EPSD	COSMIC	5.915	Down-regulation
CMGC_MAPK_p38_MAPK14_ST	P41212	ETV6	Q16539	MAPK14	S193	P194A	194	Missense	proximal	1	no	12.269	5.951	EPSD	COSMIC;GDSC;CCLE	5.915	Down-regulation
CMGC_MAPK_p38_MAPK14_ST	P41212	ETV6	Q16539	MAPK14	S193	P194L	194	Missense	proximal	1	no	12.269	4.218	EPSD	COSMIC	5.915	Loss
CMGC_MAPK_p38_MAPK14_ST	P41212	ETV6	Q16539	MAPK14	S193	P200L	200	Missense	distal	7	no	12.269	12.106	EPSD	COSMIC	5.915	Down-regulation
CMGC_MAPK_p38_MAPK14_ST	P41212	ETV6	Q16539	MAPK14	S193	I186V	186	Missense	distal	-7	no	12.269	11.985	EPSD	COSMIC	5.915	Down-regulation
CMGC_MAPK_p38_MAPK14_ST	P41212	ETV6	Q16539	MAPK14	S193	R191W	191	Missense	proximal	-2	no	12.269	11.743	EPSD	COSMIC	5.915	Down-regulation
CMGC_MAPK_p38_MAPK14_ST	P41212	ETV6	Q16539	MAPK14	S203	L201P	201	Missense	proximal	-2	no	9.812	11.192	EPSD	COSMIC	5.915	Up-regulation
CMGC_MAPK_p38_MAPK14_ST	P41212	ETV6	Q16539	MAPK14	S203	P204S	204	Missense	proximal	1	no	9.812	2.528	EPSD	COSMIC	5.915	Loss
CMGC_MAPK_p38_MAPK14_ST	P41212	ETV6	Q16539	MAPK14	S203	P200L	200	Missense	distal	-3	no	9.812	8.845	EPSD	COSMIC	5.915	Down-regulation
CMGC_MAPK_p38_MAPK14_ST	P41212	ETV6	Q16539	MAPK14	S213	R211C	211	Missense	proximal	-2	no	9.084	8.149	EPSD	COSMIC	5.915	Down-regulation
CMGC_MAPK_p38_MAPK14_ST	P41212	ETV6	Q16539	MAPK14	S213	S213F	213	Missense	central	0	yes	9.084	0.000	EPSD	COSMIC	5.915	Loss
CMGC_MAPK_p38_MAPK14_ST	P41212	ETV6	Q16539	MAPK14	S213	A218T	218	Missense	distal	5	no	9.084	9.556	EPSD	COSMIC	5.915	Up-regulation
CMGC_MAPK_p38_MAPK14_ST	P41212	ETV6	Q16539	MAPK14	S238	C245Y	245	Missense	distal	7	no	11.284	11.891	EPSD	COSMIC	5.915	Up-regulation
CMGC_MAPK_p38_MAPK14_ST	P41212	ETV6	Q16539	MAPK14	S238	H244Y	244	Missense	distal	6	no	11.284	11.410	EPSD	COSMIC	5.915	Up-regulation
CMGC_MAPK_p38_MAPK14_ST	P41212	ETV6	Q16539	MAPK14	S238	S236L	236	Missense	proximal	-2	no	11.284	10.392	EPSD	COSMIC	5.915	Down-regulation
CMGC_MAPK_p38_MAPK14_ST	P41212	ETV6	Q16539	MAPK14	S238	P239S	239	Missense	proximal	1	no	11.284	4.000	EPSD	COSMIC	5.915	Loss
CMGC_MAPK_p38_MAPK14_ST	P41212	ETV6	Q16539	MAPK14	S238	E231Q	231	Missense	distal	-7	no	11.284	10.870	EPSD	COSMIC	5.915	Down-regulation
CMGC_MAPK_p38_MAPK14_ST	P41212	ETV6	Q16539	MAPK14	S257	R259W	259	Missense	proximal	2	no	13.479	12.980	PhosphoSitePlus;EPSD	COSMIC	5.915	Down-regulation
CMGC_MAPK_p38_MAPK14_ST	P41212	ETV6	Q16539	MAPK14	S257	R259Q	259	Missense	proximal	2	no	13.479	13.052	PhosphoSitePlus;EPSD	COSMIC	5.915	Down-regulation
CMGC_MAPK_p38_MAPK14_ST	P41212	ETV6	Q16539	MAPK14	S257	E261K	261	Missense	distal	4	no	13.479	13.013	PhosphoSitePlus;EPSD	COSMIC	5.915	Down-regulation
CMGC_MAPK_p38_MAPK14_ST	P41212	ETV6	Q16539	MAPK14	S257	R259G	259	Missense	proximal	2	no	13.479	13.395	PhosphoSitePlus;EPSD	COSMIC	5.915	Down-regulation
CMGC_MAPK_p38_MAPK14_ST	P41212	ETV6	Q16539	MAPK14	S257	P253S	253	Missense	distal	-4	no	13.479	13.391	PhosphoSitePlus;EPSD	COSMIC	5.915	Down-regulation
CMGC_MAPK_p38_MAPK14_ST	P41212	ETV6	Q16539	MAPK14	S271	P270S	270	Missense	proximal	-1	no	7.629	7.536	EPSD	COSMIC	5.915	Down-regulation
CMGC_MAPK_p38_MAPK14_ST	P41212	ETV6	Q16539	MAPK14	S271	P272R	272	Missense	proximal	1	no	7.629	-0.307	EPSD	COSMIC	5.915	Loss
CMGC_MAPK_p38_MAPK14_ST	P41212	ETV6	Q16539	MAPK14	S271	L277P	277	Missense	distal	6	no	7.629	7.768	EPSD	COSMIC	5.915	Up-regulation
CMGC_MAPK_p38_MAPK14_ST	P41212	ETV6	Q16539	MAPK14	S323	P324Q	324	Missense	proximal	1	no	9.215	2.007	EPSD	COSMIC	5.915	Loss
CMGC_MAPK_p38_MAPK14_ST	P41212	ETV6	Q16539	MAPK14	S323	A329T	329	Missense	distal	6	no	9.215	9.198	EPSD	COSMIC	5.915	Down-regulation
CMGC_MAPK_p38_MAPK14_ST	P41212	ETV6	Q16539	MAPK14	S323	H328Y	328	Missense	distal	5	no	9.215	9.941	EPSD	COSMIC;GDSC;CCLE	5.915	Up-regulation
CMGC_MAPK_p38_MAPK14_ST	P41212	ETV6	Q16539	MAPK14	T422	S428G	428	Missense	distal	6	no	7.739	7.860	EPSD	COSMIC	5.915	Up-regulation
CMGC_MAPK_p38_MAPK14_ST	P41212	ETV6	Q16539	MAPK14	T422	E425G	425	Missense	distal	3	no	7.739	7.785	EPSD	COSMIC	5.915	Up-regulation
CMGC_MAPK_p38_MAPK14_ST	P41212	ETV6	Q16539	MAPK14	T422	S428N	428	Missense	distal	6	no	7.739	7.719	EPSD	COSMIC;GDSC;CCLE	5.915	Down-regulation
CMGC_MAPK_p38_MAPK14_ST	P41212	ETV6	Q16539	MAPK14	T422	R418G	418	Missense	distal	-4	no	7.739	7.726	EPSD	COSMIC	5.915	Down-regulation
CMGC_MAPK_p38_MAPK14_ST	P41212	ETV6	Q16539	MAPK14	T422	F417L	417	Missense	distal	-5	no	7.739	7.683	EPSD	COSMIC	5.915	Down-regulation
CMGC_MAPK_p38_MAPK14_ST	P41212	ETV6	Q16539	MAPK14	T422	L415V	415	Missense	distal	-7	no	7.739	7.315	EPSD	COSMIC	5.915	Down-regulation
CMGC_MAPK_p38_MAPK14_ST	P41212	ETV6	Q16539	MAPK14	T422	F417C	417	Missense	distal	-5	no	7.739	7.655	EPSD	COSMIC	5.915	Down-regulation
CMGC_MAPK_p38_MAPK14_ST	P41212	ETV6	Q16539	MAPK14	T422	M427I	427	Missense	distal	5	no	7.739	7.125	EPSD	COSMIC	5.915	Down-regulation
CMGC_MAPK_p38_MAPK14_ST	P41212	ETV6	Q16539	MAPK14	T422	R418M	418	Missense	distal	-4	no	7.739	7.799	EPSD	COSMIC	5.915	Up-regulation
CMGC_MAPK_p38_MAPK14_ST	P41212	ETV6	Q16539	MAPK14	T422	M420I	420	Missense	proximal	-2	no	7.739	7.733	EPSD	COSMIC	5.915	Down-regulation
CMGC_MAPK_p38_MAPK14_ST	P41212	ETV6	Q16539	MAPK14	T431	R430L	430	Missense	proximal	-1	no	6.316	6.702	EPSD	COSMIC	5.915	Up-regulation
CMGC_MAPK_p38_MAPK14_ST	P41212	ETV6	Q16539	MAPK14	T431	S428G	428	Missense	distal	-3	no	6.316	5.379	EPSD	COSMIC	5.915	Loss
CMGC_MAPK_p38_MAPK14_ST	P41212	ETV6	Q16539	MAPK14	T431	E425G	425	Missense	distal	-6	no	6.316	6.006	EPSD	COSMIC	5.915	Down-regulation
CMGC_MAPK_p38_MAPK14_ST	P41212	ETV6	Q16539	MAPK14	T431	S428N	428	Missense	distal	-3	no	6.316	5.169	EPSD	COSMIC;GDSC;CCLE	5.915	Loss
CMGC_MAPK_p38_MAPK14_ST	P41212	ETV6	Q16539	MAPK14	T431	R430Q	430	Missense	proximal	-1	no	6.316	6.405	EPSD	COSMIC	5.915	Up-regulation
CMGC_MAPK_p38_MAPK14_ST	P41212	ETV6	Q16539	MAPK14	T431	M427I	427	Missense	distal	-4	no	6.316	6.412	EPSD	COSMIC	5.915	Up-regulation
CMGC_MAPK_p38_MAPK14_ST	P41212	ETV6	Q16539	MAPK14	T431	L434V	434	Missense	distal	3	no	6.316	6.285	EPSD	COSMIC	5.915	Down-regulation
CMGC_MAPK_p38_MAPK14_ST	P19419	ELK1	Q16539	MAPK14	T133	P131Q	131	Missense	proximal	-2	no	8.653	7.637	EPSD	COSMIC	5.915	Down-regulation
CMGC_MAPK_p38_MAPK14_ST	P19419	ELK1	Q16539	MAPK14	T133	K130N	130	Missense	distal	-3	no	8.653	8.681	EPSD	COSMIC	5.915	Up-regulation
CMGC_MAPK_p38_MAPK14_ST	P19419	ELK1	Q16539	MAPK14	T133	P134S	134	Missense	proximal	1	no	8.653	1.369	EPSD	COSMIC	5.915	Loss
CMGC_MAPK_p38_MAPK14_ST	P19419	ELK1	Q16539	MAPK14	S304	P305S	305	Missense	proximal	1	no	11.437	4.153	EPSD	COSMIC	5.915	Loss
CMGC_MAPK_p38_MAPK14_ST	P19419	ELK1	Q16539	MAPK14	S304	Q309R	309	Missense	distal	5	no	11.437	11.786	EPSD	COSMIC	5.915	Up-regulation
CMGC_MAPK_p38_MAPK14_ST	P19419	ELK1	Q16539	MAPK14	T336	R335W	335	Missense	proximal	-1	no	12.299	12.587	EPSD	COSMIC	5.915	Up-regulation
CMGC_MAPK_p38_MAPK14_ST	P19419	ELK1	Q16539	MAPK14	T353	Q346H	346	Missense	distal	-7	no	9.167	8.967	EPSD	COSMIC	5.915	Down-regulation
CMGC_MAPK_p38_MAPK14_ST	P19419	ELK1	Q16539	MAPK14	T353	A351G	351	Missense	proximal	-2	no	9.167	8.891	EPSD	COSMIC	5.915	Down-regulation
CMGC_MAPK_p38_MAPK14_ST	P19419	ELK1	Q16539	MAPK14	S383	R388C	388	Missense	distal	5	no	11.683	10.813	EPSD;PhosphoSitePlus	COSMIC	5.915	Down-regulation
CMGC_MAPK_p38_MAPK14_ST	P19419	ELK1	Q16539	MAPK14	S383	S380I	380	Missense	distal	-3	no	11.683	9.611	EPSD;PhosphoSitePlus	COSMIC	5.915	Down-regulation
CMGC_MAPK_p38_MAPK14_ST	P19419	ELK1	Q16539	MAPK14	S389	S394P	394	Missense	distal	5	no	13.211	12.760	PhosphoSitePlus;EPSD	COSMIC;GDSC;CCLE	5.915	Down-regulation
CMGC_MAPK_p38_MAPK14_ST	P19419	ELK1	Q16539	MAPK14	S389	R388C	388	Missense	proximal	-1	no	13.211	13.474	PhosphoSitePlus;EPSD	COSMIC	5.915	Up-regulation
CMGC_MAPK_p38_MAPK14_ST	P19419	ELK1	Q16539	MAPK14	S389	S394F	394	Missense	distal	5	no	13.211	11.769	PhosphoSitePlus;EPSD	COSMIC	5.915	Down-regulation
CMGC_MAPK_p38_MAPK14_ST	P19419	ELK1	Q16539	MAPK14	S422	P425S	425	Missense	distal	3	no	12.846	12.806	EPSD	COSMIC	5.915	Down-regulation
CMGC_MAPK_p38_MAPK14_ST	P21462	FPR1	Q16539	MAPK14	S332	T336I	336	Missense	distal	4	no	6.497	5.970	EPSD	COSMIC	5.915	Down-regulation
CMGC_MAPK_p38_MAPK14_ST	P21462	FPR1	Q16539	MAPK14	S338	T336I	336	Missense	proximal	-2	no	6.555	6.456	EPSD	COSMIC	5.915	Down-regulation
CMGC_MAPK_p38_MAPK14_ST	P21462	FPR1	Q16539	MAPK14	S338	E344V	344	Missense	distal	6	no	6.555	6.234	EPSD	COSMIC;GDSC;CCLE	5.915	Down-regulation
CMGC_MAPK_p38_MAPK14_ST	P21462	FPR1	Q16539	MAPK14	S342	T336I	336	Missense	distal	-6	no	6.506	5.484	PhosphoSitePlus	COSMIC	5.915	Loss
CMGC_MAPK_p38_MAPK14_ST	P21462	FPR1	Q16539	MAPK14	S342	E346D	346	Missense	distal	4	no	6.506	4.836	PhosphoSitePlus	COSMIC	5.915	Loss
CMGC_MAPK_p38_MAPK14_ST	P21462	FPR1	Q16539	MAPK14	S342	E344V	344	Missense	proximal	2	no	6.506	6.113	PhosphoSitePlus	COSMIC;GDSC;CCLE	5.915	Down-regulation
CMGC_MAPK_p38_MAPK14_ST	Q969V6	MRTFA	Q16539	MAPK14	S6	L4F	4	Missense	proximal	-2	no	8.612	8.780	EPSD	COSMIC	5.915	Up-regulation
CMGC_MAPK_p38_MAPK14_ST	Q969V6	MRTFA	Q16539	MAPK14	S6	P2S	2	Missense	distal	-4	no	8.612	8.525	EPSD	COSMIC	5.915	Down-regulation
CMGC_MAPK_p38_MAPK14_ST	Q969V6	MRTFA	Q16539	MAPK14	S6	E12D	12	Missense	distal	6	no	8.612	8.512	EPSD	COSMIC	5.915	Down-regulation
CMGC_MAPK_p38_MAPK14_ST	Q969V6	MRTFA	Q16539	MAPK14	S6	P2L	2	Missense	distal	-4	no	8.612	9.125	EPSD	COSMIC	5.915	Up-regulation
CMGC_MAPK_p38_MAPK14_ST	Q969V6	MRTFA	Q16539	MAPK14	S6	K5E	5	Missense	proximal	-1	no	8.612	8.551	EPSD	COSMIC	5.915	Down-regulation
CMGC_MAPK_p38_MAPK14_ST	Q969V6	MRTFA	Q16539	MAPK14	S6	P2R	2	Missense	distal	-4	no	8.612	8.536	EPSD	COSMIC	5.915	Down-regulation
CMGC_MAPK_p38_MAPK14_ST	Q969V6	MRTFA	Q16539	MAPK14	S119	S114C	114	Missense	distal	-5	no	5.666	6.367	EPSD	COSMIC	5.915	Gain
CMGC_MAPK_p38_MAPK14_ST	Q969V6	MRTFA	Q16539	MAPK14	S124	E126G	126	Missense	proximal	2	no	10.506	10.312	EPSD	COSMIC	5.915	Down-regulation
CMGC_MAPK_p38_MAPK14_ST	Q969V6	MRTFA	Q16539	MAPK14	S124	E126K	126	Missense	proximal	2	no	10.506	10.192	EPSD	COSMIC	5.915	Down-regulation
CMGC_MAPK_p38_MAPK14_ST	Q969V6	MRTFA	Q16539	MAPK14	S124	P125L	125	Missense	proximal	1	no	10.506	2.456	EPSD	COSMIC	5.915	Loss
CMGC_MAPK_p38_MAPK14_ST	Q969V6	MRTFA	Q16539	MAPK14	S124	D121N	121	Missense	distal	-3	no	10.506	10.348	EPSD	COSMIC	5.915	Down-regulation
CMGC_MAPK_p38_MAPK14_ST	Q969V6	MRTFA	Q16539	MAPK14	S124	E117K	117	Missense	distal	-7	no	10.506	10.452	EPSD	COSMIC	5.915	Down-regulation
CMGC_MAPK_p38_MAPK14_ST	Q969V6	MRTFA	Q16539	MAPK14	S139	P138L	138	Missense	proximal	-1	no	12.731	12.916	EPSD	COSMIC	5.915	Up-regulation
CMGC_MAPK_p38_MAPK14_ST	Q969V6	MRTFA	Q16539	MAPK14	S139	R144G	144	Missense	distal	5	no	12.731	12.785	EPSD	COSMIC	5.915	Up-regulation
CMGC_MAPK_p38_MAPK14_ST	Q969V6	MRTFA	Q16539	MAPK14	S156	P157H	157	Missense	proximal	1	no	10.277	-3.377	EPSD	COSMIC	5.915	Loss
CMGC_MAPK_p38_MAPK14_ST	Q969V6	MRTFA	Q16539	MAPK14	S156	S154C	154	Missense	proximal	-2	no	10.277	9.142	EPSD	COSMIC	5.915	Down-regulation
CMGC_MAPK_p38_MAPK14_ST	Q969V6	MRTFA	Q16539	MAPK14	S156	P157S	157	Missense	proximal	1	no	10.277	2.993	EPSD	COSMIC	5.915	Loss
CMGC_MAPK_p38_MAPK14_ST	Q969V6	MRTFA	Q16539	MAPK14	S156	Q163P	163	Missense	distal	7	no	10.277	10.214	EPSD	COSMIC	5.915	Down-regulation
CMGC_MAPK_p38_MAPK14_ST	Q969V6	MRTFA	Q16539	MAPK14	S162	Q163P	163	Missense	proximal	1	no	5.580	12.788	EPSD	COSMIC	5.915	Gain
CMGC_MAPK_p38_MAPK14_ST	Q969V6	MRTFA	Q16539	MAPK14	T204	P205S	205	Missense	proximal	1	no	10.178	2.895	EPSD	COSMIC	5.915	Loss
CMGC_MAPK_p38_MAPK14_ST	Q969V6	MRTFA	Q16539	MAPK14	T204	P205H	205	Missense	proximal	1	no	10.178	-3.475	EPSD	COSMIC	5.915	Loss
CMGC_MAPK_p38_MAPK14_ST	Q969V6	MRTFA	Q16539	MAPK14	T204	K202T	202	Missense	proximal	-2	no	10.178	10.750	EPSD	COSMIC	5.915	Up-regulation
CMGC_MAPK_p38_MAPK14_ST	Q969V6	MRTFA	Q16539	MAPK14	T204	K202E	202	Missense	proximal	-2	no	10.178	11.209	EPSD	COSMIC	5.915	Up-regulation
CMGC_MAPK_p38_MAPK14_ST	Q969V6	MRTFA	Q16539	MAPK14	T204	P205L	205	Missense	proximal	1	no	10.178	2.128	EPSD	COSMIC	5.915	Loss
CMGC_MAPK_p38_MAPK14_ST	Q969V6	MRTFA	Q16539	MAPK14	T305	P307S	307	Missense	proximal	2	no	13.787	14.163	EPSD	COSMIC	5.915	Up-regulation
CMGC_MAPK_p38_MAPK14_ST	Q969V6	MRTFA	Q16539	MAPK14	T305	R309C	309	Missense	distal	4	no	13.787	13.352	EPSD	COSMIC	5.915	Down-regulation
CMGC_MAPK_p38_MAPK14_ST	Q969V6	MRTFA	Q16539	MAPK14	T305	E298K	298	Missense	distal	-7	no	13.787	13.733	EPSD	COSMIC	5.915	Down-regulation
CMGC_MAPK_p38_MAPK14_ST	Q969V6	MRTFA	Q16539	MAPK14	T305	S312P	312	Missense	distal	7	no	13.787	13.565	EPSD	COSMIC	5.915	Down-regulation
CMGC_MAPK_p38_MAPK14_ST	Q969V6	MRTFA	Q16539	MAPK14	T305	S302R	302	Missense	distal	-3	no	13.787	14.299	EPSD	COSMIC	5.915	Up-regulation
CMGC_MAPK_p38_MAPK14_ST	Q969V6	MRTFA	Q16539	MAPK14	T305	S303R	303	Missense	proximal	-2	no	13.787	13.587	EPSD	COSMIC	5.915	Down-regulation
CMGC_MAPK_p38_MAPK14_ST	Q969V6	MRTFA	Q16539	MAPK14	S312	S319G	319	Missense	distal	7	no	7.438	7.295	EPSD;PhosphoSitePlus	COSMIC	5.915	Down-regulation
CMGC_MAPK_p38_MAPK14_ST	Q969V6	MRTFA	Q16539	MAPK14	S312	P307S	307	Missense	distal	-5	no	7.438	6.991	EPSD;PhosphoSitePlus	COSMIC	5.915	Down-regulation
CMGC_MAPK_p38_MAPK14_ST	Q969V6	MRTFA	Q16539	MAPK14	S312	R309C	309	Missense	distal	-3	no	7.438	5.243	EPSD;PhosphoSitePlus	COSMIC	5.915	Loss
CMGC_MAPK_p38_MAPK14_ST	Q969V6	MRTFA	Q16539	MAPK14	S312	S312P	312	Missense	central	0	yes	7.438	0.000	EPSD;PhosphoSitePlus	COSMIC	5.915	Loss
CMGC_MAPK_p38_MAPK14_ST	Q969V6	MRTFA	Q16539	MAPK14	S316	S319G	319	Missense	distal	3	no	6.159	6.201	EPSD	COSMIC	5.915	Up-regulation
CMGC_MAPK_p38_MAPK14_ST	Q969V6	MRTFA	Q16539	MAPK14	S316	R309C	309	Missense	distal	-7	no	6.159	5.767	EPSD	COSMIC	5.915	Loss
CMGC_MAPK_p38_MAPK14_ST	Q969V6	MRTFA	Q16539	MAPK14	S316	S320L	320	Missense	distal	4	no	6.159	5.080	EPSD	COSMIC	5.915	Loss
CMGC_MAPK_p38_MAPK14_ST	Q969V6	MRTFA	Q16539	MAPK14	S316	S312P	312	Missense	distal	-4	no	6.159	6.247	EPSD	COSMIC	5.915	Up-regulation
CMGC_MAPK_p38_MAPK14_ST	Q969V6	MRTFA	Q16539	MAPK14	S316	S320G	320	Missense	distal	4	no	6.159	5.927	EPSD	COSMIC	5.915	Down-regulation
CMGC_MAPK_p38_MAPK14_ST	Q969V6	MRTFA	Q16539	MAPK14	S318	S319G	319	Missense	proximal	1	no	6.803	6.291	EPSD	COSMIC	5.915	Down-regulation
CMGC_MAPK_p38_MAPK14_ST	Q969V6	MRTFA	Q16539	MAPK14	S318	S320L	320	Missense	proximal	2	no	6.803	6.314	EPSD	COSMIC	5.915	Down-regulation
CMGC_MAPK_p38_MAPK14_ST	Q969V6	MRTFA	Q16539	MAPK14	S318	S312P	312	Missense	distal	-6	no	6.803	6.196	EPSD	COSMIC	5.915	Down-regulation
CMGC_MAPK_p38_MAPK14_ST	Q969V6	MRTFA	Q16539	MAPK14	S318	S320G	320	Missense	proximal	2	no	6.803	6.574	EPSD	COSMIC	5.915	Down-regulation
CMGC_MAPK_p38_MAPK14_ST	Q969V6	MRTFA	Q16539	MAPK14	S333	L328I	328	Missense	distal	-5	no	6.519	6.190	PhosphoSitePlus;EPSD	COSMIC	5.915	Down-regulation
CMGC_MAPK_p38_MAPK14_ST	Q969V6	MRTFA	Q16539	MAPK14	S333	G327W	327	Missense	distal	-6	no	6.519	5.576	PhosphoSitePlus;EPSD	COSMIC	5.915	Loss
CMGC_MAPK_p38_MAPK14_ST	Q969V6	MRTFA	Q16539	MAPK14	S333	R330H	330	Missense	distal	-3	no	6.519	4.766	PhosphoSitePlus;EPSD	COSMIC	5.915	Loss
CMGC_MAPK_p38_MAPK14_ST	Q969V6	MRTFA	Q16539	MAPK14	S333	R330C	330	Missense	distal	-3	no	6.519	4.324	PhosphoSitePlus;EPSD	COSMIC	5.915	Loss
CMGC_MAPK_p38_MAPK14_ST	Q969V6	MRTFA	Q16539	MAPK14	S385	P391L	391	Missense	distal	6	no	10.755	10.616	EPSD	COSMIC	5.915	Down-regulation
CMGC_MAPK_p38_MAPK14_ST	Q969V6	MRTFA	Q16539	MAPK14	T450	P457S	457	Missense	distal	7	no	11.064	11.286	EPSD	COSMIC	5.915	Up-regulation
CMGC_MAPK_p38_MAPK14_ST	Q969V6	MRTFA	Q16539	MAPK14	T450	G448S	448	Missense	proximal	-2	no	11.064	11.514	EPSD	COSMIC	5.915	Up-regulation
CMGC_MAPK_p38_MAPK14_ST	Q969V6	MRTFA	Q16539	MAPK14	T450	P451S	451	Missense	proximal	1	no	11.064	3.780	EPSD	COSMIC	5.915	Loss
CMGC_MAPK_p38_MAPK14_ST	Q969V6	MRTFA	Q16539	MAPK14	T450	T447M	447	Missense	distal	-3	no	11.064	9.958	EPSD	COSMIC	5.915	Down-regulation
CMGC_MAPK_p38_MAPK14_ST	Q969V6	MRTFA	Q16539	MAPK14	T450	P452S	452	Missense	proximal	2	no	11.064	11.441	EPSD	COSMIC	5.915	Up-regulation
CMGC_MAPK_p38_MAPK14_ST	Q969V6	MRTFA	Q16539	MAPK14	S454	P457S	457	Missense	distal	3	no	13.149	13.109	EPSD	COSMIC	5.915	Down-regulation
CMGC_MAPK_p38_MAPK14_ST	Q969V6	MRTFA	Q16539	MAPK14	S454	R460H	460	Missense	distal	6	no	13.149	13.041	EPSD	COSMIC	5.915	Down-regulation
CMGC_MAPK_p38_MAPK14_ST	Q969V6	MRTFA	Q16539	MAPK14	S454	G448S	448	Missense	distal	-6	no	13.149	13.629	EPSD	COSMIC	5.915	Up-regulation
CMGC_MAPK_p38_MAPK14_ST	Q969V6	MRTFA	Q16539	MAPK14	S454	P451S	451	Missense	distal	-3	no	13.149	13.912	EPSD	COSMIC	5.915	Up-regulation
CMGC_MAPK_p38_MAPK14_ST	Q969V6	MRTFA	Q16539	MAPK14	S454	R460L	460	Missense	distal	6	no	13.149	13.022	EPSD	COSMIC	5.915	Down-regulation
CMGC_MAPK_p38_MAPK14_ST	Q969V6	MRTFA	Q16539	MAPK14	S454	T447M	447	Missense	distal	-7	no	13.149	13.203	EPSD	COSMIC	5.915	Up-regulation
CMGC_MAPK_p38_MAPK14_ST	Q969V6	MRTFA	Q16539	MAPK14	S454	P452S	452	Missense	proximal	-2	no	13.149	12.660	EPSD	COSMIC	5.915	Down-regulation
CMGC_MAPK_p38_MAPK14_ST	Q969V6	MRTFA	Q16539	MAPK14	T456	P457S	457	Missense	proximal	1	no	10.100	2.816	EPSD	COSMIC	5.915	Loss
CMGC_MAPK_p38_MAPK14_ST	Q969V6	MRTFA	Q16539	MAPK14	T456	R460H	460	Missense	distal	4	no	10.100	9.706	EPSD	COSMIC	5.915	Down-regulation
CMGC_MAPK_p38_MAPK14_ST	Q969V6	MRTFA	Q16539	MAPK14	T456	P451S	451	Missense	distal	-5	no	10.100	9.652	EPSD	COSMIC	5.915	Down-regulation
CMGC_MAPK_p38_MAPK14_ST	Q969V6	MRTFA	Q16539	MAPK14	T456	R460L	460	Missense	distal	4	no	10.100	9.738	EPSD	COSMIC	5.915	Down-regulation
CMGC_MAPK_p38_MAPK14_ST	Q969V6	MRTFA	Q16539	MAPK14	T456	P452S	452	Missense	distal	-4	no	10.100	10.012	EPSD	COSMIC	5.915	Down-regulation
CMGC_MAPK_p38_MAPK14_ST	Q969V6	MRTFA	Q16539	MAPK14	T471	G477C	477	Missense	distal	6	no	9.478	9.082	EPSD	COSMIC	5.915	Down-regulation
CMGC_MAPK_p38_MAPK14_ST	Q969V6	MRTFA	Q16539	MAPK14	T471	G473V	473	Missense	proximal	2	no	9.478	9.280	EPSD	COSMIC	5.915	Down-regulation
CMGC_MAPK_p38_MAPK14_ST	Q969V6	MRTFA	Q16539	MAPK14	T471	P472H	472	Missense	proximal	1	no	9.478	-4.175	EPSD	COSMIC	5.915	Loss
CMGC_MAPK_p38_MAPK14_ST	Q969V6	MRTFA	Q16539	MAPK14	T471	G473R	473	Missense	proximal	2	no	9.478	9.562	EPSD	COSMIC	5.915	Up-regulation
CMGC_MAPK_p38_MAPK14_ST	Q969V6	MRTFA	Q16539	MAPK14	T471	E468D	468	Missense	distal	-3	no	9.478	9.272	EPSD	COSMIC	5.915	Down-regulation
CMGC_MAPK_p38_MAPK14_ST	Q969V6	MRTFA	Q16539	MAPK14	T471	D474G	474	Missense	distal	3	no	9.478	9.469	EPSD	COSMIC	5.915	Down-regulation
CMGC_MAPK_p38_MAPK14_ST	Q969V6	MRTFA	Q16539	MAPK14	T471	E468K	468	Missense	distal	-3	no	9.478	9.086	EPSD	COSMIC	5.915	Down-regulation
CMGC_MAPK_p38_MAPK14_ST	Q969V6	MRTFA	Q16539	MAPK14	T471	D474Y	474	Missense	distal	3	no	9.478	9.469	EPSD	COSMIC	5.915	Down-regulation
CMGC_MAPK_p38_MAPK14_ST	Q969V6	MRTFA	Q16539	MAPK14	T471	P472T	472	Missense	proximal	1	no	9.478	2.025	EPSD	COSMIC	5.915	Loss
CMGC_MAPK_p38_MAPK14_ST	Q969V6	MRTFA	Q16539	MAPK14	S482	G477C	477	Missense	distal	-5	no	7.066	7.386	EPSD	COSMIC	5.915	Up-regulation
CMGC_MAPK_p38_MAPK14_ST	Q969V6	MRTFA	Q16539	MAPK14	S482	M479T	479	Missense	distal	-3	no	7.066	8.172	EPSD	COSMIC	5.915	Up-regulation
CMGC_MAPK_p38_MAPK14_ST	Q969V6	MRTFA	Q16539	MAPK14	S482	T485M	485	Missense	distal	3	no	7.066	7.090	EPSD	COSMIC	5.915	Up-regulation
CMGC_MAPK_p38_MAPK14_ST	Q969V6	MRTFA	Q16539	MAPK14	S482	L489P	489	Missense	distal	7	no	7.066	7.229	EPSD	COSMIC	5.915	Up-regulation
CMGC_MAPK_p38_MAPK14_ST	Q969V6	MRTFA	Q16539	MAPK14	S482	T488A	488	Missense	distal	6	no	7.066	7.084	EPSD	COSMIC	5.915	Up-regulation
CMGC_MAPK_p38_MAPK14_ST	Q969V6	MRTFA	Q16539	MAPK14	S482	T485A	485	Missense	distal	3	no	7.066	7.067	EPSD	COSMIC	5.915	Up-regulation
CMGC_MAPK_p38_MAPK14_ST	Q969V6	MRTFA	Q16539	MAPK14	S482	P483H	483	Missense	proximal	1	no	7.066	-6.588	EPSD	COSMIC	5.915	Loss
CMGC_MAPK_p38_MAPK14_ST	Q969V6	MRTFA	Q16539	MAPK14	S482	T488M	488	Missense	distal	6	no	7.066	7.077	EPSD	COSMIC	5.915	Up-regulation
CMGC_MAPK_p38_MAPK14_ST	Q969V6	MRTFA	Q16539	MAPK14	S511	A516G	516	Missense	distal	5	no	7.850	8.233	EPSD	COSMIC	5.915	Up-regulation
CMGC_MAPK_p38_MAPK14_ST	Q969V6	MRTFA	Q16539	MAPK14	S511	A516T	516	Missense	distal	5	no	7.850	8.322	EPSD	COSMIC	5.915	Up-regulation
CMGC_MAPK_p38_MAPK14_ST	Q969V6	MRTFA	Q16539	MAPK14	S511	P512H	512	Missense	proximal	1	no	7.850	-5.804	EPSD	COSMIC	5.915	Loss
CMGC_MAPK_p38_MAPK14_ST	Q969V6	MRTFA	Q16539	MAPK14	S511	G513E	513	Missense	proximal	2	no	7.850	8.044	EPSD	COSMIC	5.915	Up-regulation
CMGC_MAPK_p38_MAPK14_ST	Q969V6	MRTFA	Q16539	MAPK14	S511	P512S	512	Missense	proximal	1	no	7.850	0.566	EPSD	COSMIC	5.915	Loss
CMGC_MAPK_p38_MAPK14_ST	Q969V6	MRTFA	Q16539	MAPK14	S511	L518V	518	Missense	distal	7	no	7.850	8.148	EPSD	COSMIC	5.915	Up-regulation
CMGC_MAPK_p38_MAPK14_ST	Q969V6	MRTFA	Q16539	MAPK14	S511	C509Y	509	Missense	proximal	-2	no	7.850	8.988	EPSD	COSMIC	5.915	Up-regulation
CMGC_MAPK_p38_MAPK14_ST	Q969V6	MRTFA	Q16539	MAPK14	S511	R515L	515	Missense	distal	4	no	7.850	7.489	EPSD	COSMIC	5.915	Down-regulation
CMGC_MAPK_p38_MAPK14_ST	Q969V6	MRTFA	Q16539	MAPK14	S511	R504L	504	Missense	distal	-7	no	7.850	7.739	EPSD	COSMIC	5.915	Down-regulation
CMGC_MAPK_p38_MAPK14_ST	Q969V6	MRTFA	Q16539	MAPK14	S511	A516V	516	Missense	distal	5	no	7.850	7.832	EPSD	COSMIC	5.915	Down-regulation
CMGC_MAPK_p38_MAPK14_ST	Q969V6	MRTFA	Q16539	MAPK14	S511	R515Q	515	Missense	distal	4	no	7.850	7.646	EPSD	COSMIC	5.915	Down-regulation
CMGC_MAPK_p38_MAPK14_ST	Q969V6	MRTFA	Q16539	MAPK14	S511	R515W	515	Missense	distal	4	no	7.850	6.575	EPSD	COSMIC	5.915	Down-regulation
CMGC_MAPK_p38_MAPK14_ST	Q969V6	MRTFA	Q16539	MAPK14	S511	G514E	514	Missense	distal	3	no	7.850	7.804	EPSD	COSMIC	5.915	Down-regulation
CMGC_MAPK_p38_MAPK14_ST	Q969V6	MRTFA	Q16539	MAPK14	T573	L571P	571	Missense	proximal	-2	no	9.527	10.907	EPSD	COSMIC	5.915	Up-regulation
CMGC_MAPK_p38_MAPK14_ST	Q969V6	MRTFA	Q16539	MAPK14	T573	A569P	569	Missense	distal	-4	no	9.527	9.574	EPSD	COSMIC	5.915	Up-regulation
CMGC_MAPK_p38_MAPK14_ST	Q969V6	MRTFA	Q16539	MAPK14	T573	K576R	576	Missense	distal	3	no	9.527	9.511	EPSD	COSMIC	5.915	Down-regulation
CMGC_MAPK_p38_MAPK14_ST	Q969V6	MRTFA	Q16539	MAPK14	T573	A567P	567	Missense	distal	-6	no	9.527	9.463	EPSD	COSMIC	5.915	Down-regulation
CMGC_MAPK_p38_MAPK14_ST	Q969V6	MRTFA	Q16539	MAPK14	T573	P566L	566	Missense	distal	-7	no	9.527	9.334	EPSD	COSMIC	5.915	Down-regulation
CMGC_MAPK_p38_MAPK14_ST	Q969V6	MRTFA	Q16539	MAPK14	T573	T573M	573	Missense	central	0	yes	9.527	0.000	EPSD	COSMIC	5.915	Loss
CMGC_MAPK_p38_MAPK14_ST	Q969V6	MRTFA	Q16539	MAPK14	S695	S695L	695	Missense	central	0	yes	11.759	0.000	EPSD	COSMIC	5.915	Loss
CMGC_MAPK_p38_MAPK14_ST	Q969V6	MRTFA	Q16539	MAPK14	S695	A699V	699	Missense	distal	4	no	11.759	11.326	EPSD	COSMIC	5.915	Down-regulation
CMGC_MAPK_p38_MAPK14_ST	Q969V6	MRTFA	Q16539	MAPK14	S695	P698R	698	Missense	distal	3	no	11.759	11.747	EPSD	COSMIC	5.915	Down-regulation
CMGC_MAPK_p38_MAPK14_ST	Q969V6	MRTFA	Q16539	MAPK14	S695	S701F	701	Missense	distal	6	no	11.759	11.402	EPSD	COSMIC	5.915	Down-regulation
CMGC_MAPK_p38_MAPK14_ST	Q969V6	MRTFA	Q16539	MAPK14	S695	A702G	702	Missense	distal	7	no	11.759	11.594	EPSD	COSMIC	5.915	Down-regulation
CMGC_MAPK_p38_MAPK14_ST	Q969V6	MRTFA	Q16539	MAPK14	S695	S695I	695	Missense	central	0	yes	11.759	0.000	EPSD	COSMIC	5.915	Loss
CMGC_MAPK_p38_MAPK14_ST	Q969V6	MRTFA	Q16539	MAPK14	S785	P779L	779	Missense	distal	-6	no	8.119	7.506	EPSD	COSMIC	5.915	Down-regulation
CMGC_MAPK_p38_MAPK14_ST	Q969V6	MRTFA	Q16539	MAPK14	S785	S785P	785	Missense	central	0	yes	8.119	0.000	EPSD	COSMIC	5.915	Loss
CMGC_MAPK_p38_MAPK14_ST	Q969V6	MRTFA	Q16539	MAPK14	S785	P779S	779	Missense	distal	-6	no	8.119	8.726	EPSD	COSMIC	5.915	Up-regulation
CMGC_MAPK_p38_MAPK14_ST	Q969V6	MRTFA	Q16539	MAPK14	S792	S785P	785	Missense	distal	-7	no	13.464	13.377	EPSD	COSMIC	5.915	Down-regulation
CMGC_MAPK_p38_MAPK14_ST	Q969V6	MRTFA	Q16539	MAPK14	S807	R813C	813	Missense	distal	6	no	10.124	9.850	EPSD	COSMIC	5.915	Down-regulation
CMGC_MAPK_p38_MAPK14_ST	Q969V6	MRTFA	Q16539	MAPK14	S807	P808T	808	Missense	proximal	1	no	10.124	2.671	EPSD	COSMIC	5.915	Loss
CMGC_MAPK_p38_MAPK14_ST	Q969V6	MRTFA	Q16539	MAPK14	S807	P805A	805	Missense	proximal	-2	no	10.124	9.462	EPSD	COSMIC	5.915	Down-regulation
CMGC_MAPK_p38_MAPK14_ST	Q969V6	MRTFA	Q16539	MAPK14	S807	S809P	809	Missense	proximal	2	no	10.124	9.748	EPSD	COSMIC	5.915	Down-regulation
CMGC_MAPK_p38_MAPK14_ST	Q969V6	MRTFA	Q16539	MAPK14	S807	P803L	803	Missense	distal	-4	no	10.124	10.636	EPSD	COSMIC	5.915	Up-regulation
CMGC_MAPK_p38_MAPK14_ST	Q969V6	MRTFA	Q16539	MAPK14	S859	S859P	859	Missense	central	0	yes	11.459	0.000	EPSD	COSMIC	5.915	Loss
CMGC_MAPK_p38_MAPK14_ST	Q969V6	MRTFA	Q16539	MAPK14	S859	H856R	856	Missense	distal	-3	no	11.459	13.213	EPSD	COSMIC	5.915	Up-regulation
CMGC_MAPK_p38_MAPK14_ST	Q969V6	MRTFA	Q16539	MAPK14	S859	I853V	853	Missense	distal	-6	no	11.459	11.724	EPSD	COSMIC	5.915	Up-regulation
CMGC_MAPK_p38_MAPK14_ST	Q9UBK2	PPARGC1A	Q16539	MAPK14	S208	P202H	202	Missense	distal	-6	no	6.703	6.241	EPSD	COSMIC	5.915	Down-regulation
CMGC_MAPK_p38_MAPK14_ST	Q9UBK2	PPARGC1A	Q16539	MAPK14	S208	P202R	202	Missense	distal	-6	no	6.703	7.204	EPSD	COSMIC	5.915	Up-regulation
CMGC_MAPK_p38_MAPK14_ST	Q9UBK2	PPARGC1A	Q16539	MAPK14	S208	P202T	202	Missense	distal	-6	no	6.703	7.038	EPSD	COSMIC	5.915	Up-regulation
CMGC_MAPK_p38_MAPK14_ST	Q9UBK2	PPARGC1A	Q16539	MAPK14	S208	R205H	205	Missense	distal	-3	no	6.703	4.950	EPSD	COSMIC	5.915	Loss
CMGC_MAPK_p38_MAPK14_ST	Q9UBK2	PPARGC1A	Q16539	MAPK14	T263	E265K	265	Missense	proximal	2	no	10.737	10.423	PhosphoSitePlus;EPSD	COSMIC	5.915	Down-regulation
CMGC_MAPK_p38_MAPK14_ST	Q9UBK2	PPARGC1A	Q16539	MAPK14	T263	S266L	266	Missense	distal	3	no	10.737	10.811	PhosphoSitePlus;EPSD	COSMIC	5.915	Up-regulation
CMGC_MAPK_p38_MAPK14_ST	Q9UBK2	PPARGC1A	Q16539	MAPK14	T263	P264Q	264	Missense	proximal	1	no	10.737	3.528	PhosphoSitePlus;EPSD	COSMIC	5.915	Loss
CMGC_MAPK_p38_MAPK14_ST	Q9UBK2	PPARGC1A	Q16539	MAPK14	T263	P267R	267	Missense	distal	4	no	10.737	10.459	PhosphoSitePlus;EPSD	COSMIC;GDSC;CCLE	5.915	Down-regulation
CMGC_MAPK_p38_MAPK14_ST	Q9UBK2	PPARGC1A	Q16539	MAPK14	T263	P270A	270	Missense	distal	7	no	10.737	10.981	PhosphoSitePlus;EPSD	COSMIC	5.915	Up-regulation
CMGC_MAPK_p38_MAPK14_ST	Q9UBK2	PPARGC1A	Q16539	MAPK14	S266	E265K	265	Missense	proximal	-1	no	12.144	12.205	EPSD;PhosphoSitePlus	COSMIC	5.915	Up-regulation
CMGC_MAPK_p38_MAPK14_ST	Q9UBK2	PPARGC1A	Q16539	MAPK14	S266	S266L	266	Missense	central	0	yes	12.144	0.000	EPSD;PhosphoSitePlus	COSMIC	5.915	Loss
CMGC_MAPK_p38_MAPK14_ST	Q9UBK2	PPARGC1A	Q16539	MAPK14	S266	P264Q	264	Missense	proximal	-2	no	12.144	11.128	EPSD;PhosphoSitePlus	COSMIC	5.915	Down-regulation
CMGC_MAPK_p38_MAPK14_ST	Q9UBK2	PPARGC1A	Q16539	MAPK14	S266	P267R	267	Missense	proximal	1	no	12.144	4.208	EPSD;PhosphoSitePlus	COSMIC;GDSC;CCLE	5.915	Loss
CMGC_MAPK_p38_MAPK14_ST	Q9UBK2	PPARGC1A	Q16539	MAPK14	S266	P270A	270	Missense	distal	4	no	12.144	12.277	EPSD;PhosphoSitePlus	COSMIC	5.915	Up-regulation
CMGC_MAPK_p38_MAPK14_ST	Q9UBK2	PPARGC1A	Q16539	MAPK14	S273	S266L	266	Missense	distal	-7	no	10.394	10.114	EPSD	COSMIC	5.915	Down-regulation
CMGC_MAPK_p38_MAPK14_ST	Q9UBK2	PPARGC1A	Q16539	MAPK14	S273	P274A	274	Missense	proximal	1	no	10.394	4.076	EPSD	COSMIC	5.915	Loss
CMGC_MAPK_p38_MAPK14_ST	Q9UBK2	PPARGC1A	Q16539	MAPK14	S273	P267R	267	Missense	distal	-6	no	10.394	10.895	EPSD	COSMIC;GDSC;CCLE	5.915	Up-regulation
CMGC_MAPK_p38_MAPK14_ST	Q9UBK2	PPARGC1A	Q16539	MAPK14	S273	P270A	270	Missense	distal	-3	no	10.394	10.746	EPSD	COSMIC	5.915	Up-regulation
CMGC_MAPK_p38_MAPK14_ST	Q9UBK2	PPARGC1A	Q16539	MAPK14	S313	P309S	309	Missense	distal	-4	no	10.028	9.940	EPSD	COSMIC	5.915	Down-regulation
CMGC_MAPK_p38_MAPK14_ST	Q9UBK2	PPARGC1A	Q16539	MAPK14	S313	P314Q	314	Missense	proximal	1	no	10.028	2.819	EPSD	COSMIC	5.915	Loss
CMGC_MAPK_p38_MAPK14_ST	Q9UBK2	PPARGC1A	Q16539	MAPK14	S552	F558L	558	Missense	distal	6	no	9.770	9.999	EPSD	COSMIC	5.915	Up-regulation
CMGC_MAPK_p38_MAPK14_ST	Q9UBK2	PPARGC1A	Q16539	MAPK14	S552	V551M	551	Missense	proximal	-1	no	9.770	9.677	EPSD	COSMIC	5.915	Down-regulation
CMGC_MAPK_p38_MAPK14_ST	Q9UBK2	PPARGC1A	Q16539	MAPK14	S552	R548G	548	Missense	distal	-4	no	9.770	9.757	EPSD	COSMIC	5.915	Down-regulation
CMGC_MAPK_p38_MAPK14_ST	Q9UBK2	PPARGC1A	Q16539	MAPK14	S573	C578Y	578	Missense	distal	5	no	5.478	6.379	EPSD	COSMIC	5.915	Gain
CMGC_MAPK_p38_MAPK14_ST	Q9UBK2	PPARGC1A	Q16539	MAPK14	S581	C578Y	578	Missense	distal	-3	no	6.410	7.198	EPSD	COSMIC	5.915	Up-regulation
CMGC_MAPK_p38_MAPK14_ST	Q9UBK2	PPARGC1A	Q16539	MAPK14	S581	R576M	576	Missense	distal	-5	no	6.410	6.344	EPSD	COSMIC	5.915	Down-regulation
CMGC_MAPK_p38_MAPK14_ST	Q9UBK2	PPARGC1A	Q16539	MAPK14	S586	R589M	589	Missense	distal	3	no	6.449	6.459	EPSD	COSMIC	5.915	Up-regulation
CMGC_MAPK_p38_MAPK14_ST	Q9UBK2	PPARGC1A	Q16539	MAPK14	S590	R589M	589	Missense	proximal	-1	no	12.770	13.001	EPSD	COSMIC	5.915	Up-regulation
CMGC_MAPK_p38_MAPK14_ST	Q9UBK2	PPARGC1A	Q16539	MAPK14	S593	R598T	598	Missense	distal	5	no	7.958	8.102	EPSD	COSMIC	5.915	Up-regulation
CMGC_MAPK_p38_MAPK14_ST	Q9UBK2	PPARGC1A	Q16539	MAPK14	S593	R589M	589	Missense	distal	-4	no	7.958	8.019	EPSD	COSMIC	5.915	Up-regulation
CMGC_MAPK_p38_MAPK14_ST	Q9UBK2	PPARGC1A	Q16539	MAPK14	S616	R611S	611	Missense	distal	-5	no	9.507	9.288	EPSD	COSMIC	5.915	Down-regulation
CMGC_MAPK_p38_MAPK14_ST	Q9UBK2	PPARGC1A	Q16539	MAPK14	S616	L618F	618	Missense	proximal	2	no	9.507	9.330	EPSD	COSMIC	5.915	Down-regulation
CMGC_MAPK_p38_MAPK14_ST	Q9UBK2	PPARGC1A	Q16539	MAPK14	S626	R625K	625	Missense	proximal	-1	no	8.968	9.049	EPSD	COSMIC	5.915	Up-regulation
CMGC_MAPK_p38_MAPK14_ST	Q9UBK2	PPARGC1A	Q16539	MAPK14	S626	R633G	633	Missense	distal	7	no	8.968	8.790	EPSD	COSMIC	5.915	Down-regulation
CMGC_MAPK_p38_MAPK14_ST	Q9UBK2	PPARGC1A	Q16539	MAPK14	S626	R633M	633	Missense	distal	7	no	8.968	8.803	EPSD	COSMIC	5.915	Down-regulation
CMGC_MAPK_p38_MAPK14_ST	Q9UBK2	PPARGC1A	Q16539	MAPK14	S626	P632T	632	Missense	distal	6	no	8.968	8.994	EPSD	COSMIC	5.915	Up-regulation
CMGC_MAPK_p38_MAPK14_ST	Q9UBK2	PPARGC1A	Q16539	MAPK14	S626	S624L	624	Missense	proximal	-2	no	8.968	8.077	EPSD	COSMIC	5.915	Down-regulation
CMGC_MAPK_p38_MAPK14_ST	P49841	GSK3B	Q16539	MAPK14	T8	S9F	9	Missense	proximal	1	no	5.124	6.404	EPSD	COSMIC	5.915	Gain
CMGC_MAPK_p38_MAPK14_ST	P49841	GSK3B	Q16539	MAPK14	S9	S9F	9	Missense	central	0	yes	6.613	0.000	EPSD	COSMIC	5.915	Loss
CMGC_MAPK_p38_MAPK14_ST	P49841	GSK3B	Q16539	MAPK14	S9	P16A	16	Missense	distal	7	no	6.613	6.857	EPSD	COSMIC	5.915	Up-regulation
CMGC_MAPK_p38_MAPK14_ST	P49841	GSK3B	Q16539	MAPK14	S9	S2P	2	Missense	distal	-7	no	6.613	6.526	EPSD	COSMIC	5.915	Down-regulation
CMGC_MAPK_p38_MAPK14_ST	P49841	GSK3B	Q16539	MAPK14	T43	G47C	47	Missense	distal	4	no	9.712	8.793	EPSD	COSMIC	5.915	Down-regulation
CMGC_MAPK_p38_MAPK14_ST	P49841	GSK3B	Q16539	MAPK14	T43	V41G	41	Missense	proximal	-2	no	9.712	9.851	EPSD	COSMIC	5.915	Up-regulation
CMGC_MAPK_p38_MAPK14_ST	P49841	GSK3B	Q16539	MAPK14	T43	V37G	37	Missense	distal	-6	no	9.712	10.262	EPSD	COSMIC	5.915	Up-regulation
CMGC_MAPK_p38_MAPK14_ST	P49841	GSK3B	Q16539	MAPK14	T275	R278M	278	Missense	distal	3	no	8.466	8.476	EPSD	COSMIC	5.915	Up-regulation
CMGC_MAPK_p38_MAPK14_ST	P49841	GSK3B	Q16539	MAPK14	T324	R319C	319	Missense	distal	-5	no	8.820	9.302	EPSD	COSMIC	5.915	Up-regulation
CMGC_MAPK_p38_MAPK14_ST	P49841	GSK3B	Q16539	MAPK14	T324	R319Q	319	Missense	distal	-5	no	8.820	8.777	EPSD	COSMIC;GDSC	5.915	Down-regulation
CMGC_MAPK_p38_MAPK14_ST	P49841	GSK3B	Q16539	MAPK14	S389	Q385P	385	Missense	distal	-4	no	5.959	5.667	EPSD;PhosphoSitePlus	COSMIC	5.915	Loss
CMGC_MAPK_p38_MAPK14_ST	P49841	GSK3B	Q16539	MAPK14	S389	P391L	391	Missense	proximal	2	no	5.959	5.846	EPSD;PhosphoSitePlus	COSMIC	5.915	Loss
CMGC_MAPK_p38_MAPK14_ST	P49841	GSK3B	Q16539	MAPK14	T390	Q385P	385	Missense	distal	-5	no	10.297	10.569	PhosphoSitePlus;EPSD	COSMIC	5.915	Up-regulation
CMGC_MAPK_p38_MAPK14_ST	P49841	GSK3B	Q16539	MAPK14	T390	P391L	391	Missense	proximal	1	no	10.297	2.246	PhosphoSitePlus;EPSD	COSMIC	5.915	Loss
CMGC_MAPK_p38_MAPK14_ST	P49841	GSK3B	Q16539	MAPK14	T390	A397V	397	Missense	distal	7	no	10.297	10.188	PhosphoSitePlus;EPSD	COSMIC;CCLE	5.915	Down-regulation
CMGC_MAPK_p38_MAPK14_ST	P49841	GSK3B	Q16539	MAPK14	T408	R405S	405	Missense	distal	-3	no	6.839	6.327	EPSD	COSMIC	5.915	Down-regulation
CMGC_MAPK_p38_MAPK14_ST	P49841	GSK3B	Q16539	MAPK14	T408	T402I	402	Missense	distal	-6	no	6.839	5.817	EPSD	COSMIC	5.915	Loss
CMGC_MAPK_p38_MAPK14_ST	P49841	GSK3B	Q16539	MAPK14	T408	R405H	405	Missense	distal	-3	no	6.839	5.086	EPSD	COSMIC;CCLE	5.915	Loss
CMGC_MAPK_p38_MAPK14_ST	O43526	KCNQ2	Q16539	MAPK14	S45	A47V	47	Missense	proximal	2	no	6.123	5.959	EPSD	COSMIC	5.915	Down-regulation
CMGC_MAPK_p38_MAPK14_ST	O43526	KCNQ2	Q16539	MAPK14	S457	V450A	450	Missense	distal	-7	no	8.506	9.324	EPSD	COSMIC	5.915	Up-regulation
CMGC_MAPK_p38_MAPK14_ST	O43526	KCNQ2	Q16539	MAPK14	S457	A452V	452	Missense	distal	-5	no	8.506	8.997	EPSD	COSMIC	5.915	Up-regulation
CMGC_MAPK_p38_MAPK14_ST	O43526	KCNQ2	Q16539	MAPK14	S457	Q459H	459	Missense	proximal	2	no	8.506	8.549	EPSD	COSMIC;GDSC	5.915	Up-regulation
CMGC_MAPK_p38_MAPK14_ST	O43526	KCNQ2	Q16539	MAPK14	S466	P467Q	467	Missense	proximal	1	no	9.429	2.220	EPSD	COSMIC	5.915	Loss
CMGC_MAPK_p38_MAPK14_ST	O43526	KCNQ2	Q16539	MAPK14	S466	R465H	465	Missense	proximal	-1	no	9.429	9.584	EPSD	COSMIC	5.915	Up-regulation
CMGC_MAPK_p38_MAPK14_ST	O43526	KCNQ2	Q16539	MAPK14	S466	Q459H	459	Missense	distal	-7	no	9.429	9.228	EPSD	COSMIC;GDSC	5.915	Down-regulation
CMGC_MAPK_p38_MAPK14_ST	O43526	KCNQ2	Q16539	MAPK14	S466	S472C	472	Missense	distal	6	no	9.429	9.154	EPSD	COSMIC	5.915	Down-regulation
CMGC_MAPK_p38_MAPK14_ST	O43526	KCNQ2	Q16539	MAPK14	S466	A469T	469	Missense	distal	3	no	9.429	9.428	EPSD	COSMIC	5.915	Down-regulation
CMGC_MAPK_p38_MAPK14_ST	O43526	KCNQ2	Q16539	MAPK14	S468	P467Q	467	Missense	proximal	-1	no	7.928	7.817	EPSD	COSMIC	5.915	Down-regulation
CMGC_MAPK_p38_MAPK14_ST	O43526	KCNQ2	Q16539	MAPK14	S468	R465H	465	Missense	distal	-3	no	7.928	6.175	EPSD	COSMIC	5.915	Down-regulation
CMGC_MAPK_p38_MAPK14_ST	O43526	KCNQ2	Q16539	MAPK14	S468	S472C	472	Missense	distal	4	no	7.928	6.777	EPSD	COSMIC	5.915	Down-regulation
CMGC_MAPK_p38_MAPK14_ST	O43526	KCNQ2	Q16539	MAPK14	S468	A469T	469	Missense	proximal	1	no	7.928	6.794	EPSD	COSMIC	5.915	Down-regulation
CMGC_MAPK_p38_MAPK14_ST	O43526	KCNQ2	Q16539	MAPK14	S476	S483G	483	Missense	distal	7	no	9.203	9.059	EPSD	COSMIC	5.915	Down-regulation
CMGC_MAPK_p38_MAPK14_ST	O43526	KCNQ2	Q16539	MAPK14	S476	S472C	472	Missense	distal	-4	no	9.203	9.664	EPSD	COSMIC	5.915	Up-regulation
CMGC_MAPK_p38_MAPK14_ST	O43526	KCNQ2	Q16539	MAPK14	S476	A469T	469	Missense	distal	-7	no	9.203	9.020	EPSD	COSMIC	5.915	Down-regulation
CMGC_MAPK_p38_MAPK14_ST	O43526	KCNQ2	Q16539	MAPK14	S485	D488N	488	Missense	distal	3	no	8.297	8.291	EPSD	COSMIC	5.915	Down-regulation
CMGC_MAPK_p38_MAPK14_ST	O43526	KCNQ2	Q16539	MAPK14	S485	S483G	483	Missense	proximal	-2	no	8.297	7.847	EPSD	COSMIC	5.915	Down-regulation
CMGC_MAPK_p38_MAPK14_ST	O43526	KCNQ2	Q16539	MAPK14	S485	R489C	489	Missense	distal	4	no	8.297	7.863	EPSD	COSMIC;GDSC;CCLE	5.915	Down-regulation
CMGC_MAPK_p38_MAPK14_ST	O43526	KCNQ2	Q16539	MAPK14	S485	G487V	487	Missense	proximal	2	no	8.297	8.098	EPSD	COSMIC	5.915	Down-regulation
CMGC_MAPK_p38_MAPK14_ST	O43526	KCNQ2	Q16539	MAPK14	S485	R491Q	491	Missense	distal	6	no	8.297	8.309	EPSD	COSMIC	5.915	Up-regulation
CMGC_MAPK_p38_MAPK14_ST	O43526	KCNQ2	Q16539	MAPK14	S485	A492V	492	Missense	distal	7	no	8.297	8.188	EPSD	COSMIC	5.915	Down-regulation
CMGC_MAPK_p38_MAPK14_ST	O43526	KCNQ2	Q16539	MAPK14	S672	A667D	667	Missense	distal	-5	no	12.119	12.631	EPSD	COSMIC	5.915	Up-regulation
CMGC_MAPK_p38_MAPK14_ST	O43526	KCNQ2	Q16539	MAPK14	S672	P669S	669	Missense	distal	-3	no	12.119	12.883	EPSD	COSMIC	5.915	Up-regulation
CMGC_MAPK_p38_MAPK14_ST	O43526	KCNQ2	Q16539	MAPK14	S672	H679Q	679	Missense	distal	7	no	12.119	12.459	EPSD	COSMIC	5.915	Up-regulation
CMGC_MAPK_p38_MAPK14_ST	O43526	KCNQ2	Q16539	MAPK14	S672	S672R	672	Missense	central	0	yes	12.119	0.000	EPSD	COSMIC	5.915	Loss
CMGC_MAPK_p38_MAPK14_ST	O43526	KCNQ2	Q16539	MAPK14	S672	S672I	672	Missense	central	0	yes	12.119	0.000	EPSD	COSMIC	5.915	Loss
CMGC_MAPK_p38_MAPK14_ST	O43526	KCNQ2	Q16539	MAPK14	S672	A667T	667	Missense	distal	-5	no	12.119	12.448	EPSD	COSMIC	5.915	Up-regulation
CMGC_MAPK_p38_MAPK14_ST	O43526	KCNQ2	Q16539	MAPK14	S672	R677W	677	Missense	distal	5	no	12.119	11.225	EPSD	COSMIC;GDSC;CCLE	5.915	Down-regulation
CMGC_MAPK_p38_MAPK14_ST	O43526	KCNQ2	Q16539	MAPK14	S672	H679Y	679	Missense	distal	7	no	12.119	12.661	EPSD	COSMIC	5.915	Up-regulation
CMGC_MAPK_p38_MAPK14_ST	O43526	KCNQ2	Q16539	MAPK14	S672	S676I	676	Missense	distal	4	no	12.119	11.331	EPSD	COSMIC	5.915	Down-regulation
CMGC_MAPK_p38_MAPK14_ST	O43526	KCNQ2	Q16539	MAPK14	S672	S672N	672	Missense	central	0	yes	12.119	0.000	EPSD	COSMIC	5.915	Loss
CMGC_MAPK_p38_MAPK14_ST	O43526	KCNQ2	Q16539	MAPK14	S731	G727D	727	Missense	distal	-4	no	10.477	10.972	EPSD	COSMIC	5.915	Up-regulation
CMGC_MAPK_p38_MAPK14_ST	O43526	KCNQ2	Q16539	MAPK14	S731	R725C	725	Missense	distal	-6	no	10.477	9.291	EPSD	COSMIC	5.915	Down-regulation
CMGC_MAPK_p38_MAPK14_ST	Q9BUB5	MKNK1	Q16539	MAPK14	S221	E220K	220	Missense	proximal	-1	no	9.256	9.317	EPSD	COSMIC	5.915	Up-regulation
CMGC_MAPK_p38_MAPK14_ST	Q9BUB5	MKNK1	Q16539	MAPK14	S221	P214S	214	Missense	distal	-7	no	9.256	9.343	EPSD	COSMIC	5.915	Up-regulation
CMGC_MAPK_p38_MAPK14_ST	Q9BUB5	MKNK1	Q16539	MAPK14	S221	N216I	216	Missense	distal	-5	no	9.256	9.192	EPSD	COSMIC	5.915	Down-regulation
CMGC_MAPK_p38_MAPK14_ST	Q9BUB5	MKNK1	Q16539	MAPK14	S226	D232Y	232	Missense	distal	6	no	7.833	7.872	EPSD	COSMIC	5.915	Up-regulation
CMGC_MAPK_p38_MAPK14_ST	Q9BUB5	MKNK1	Q16539	MAPK14	S226	E220K	220	Missense	distal	-6	no	7.833	7.419	EPSD	COSMIC	5.915	Down-regulation
CMGC_MAPK_p38_MAPK14_ST	Q9BUB5	MKNK1	Q16539	MAPK14	T250	T249P	249	Missense	proximal	-1	no	11.036	11.012	EPSD;PhosphoSitePlus	COSMIC	5.915	Down-regulation
CMGC_MAPK_p38_MAPK14_ST	Q9BUB5	MKNK1	Q16539	MAPK14	T250	T249I	249	Missense	proximal	-1	no	11.036	10.898	EPSD;PhosphoSitePlus	COSMIC	5.915	Down-regulation
CMGC_MAPK_p38_MAPK14_ST	Q9BUB5	MKNK1	Q16539	MAPK14	T250	T254S	254	Missense	distal	4	no	11.036	11.298	EPSD;PhosphoSitePlus	COSMIC	5.915	Up-regulation
CMGC_MAPK_p38_MAPK14_ST	Q9BUB5	MKNK1	Q16539	MAPK14	T250	S244Y	244	Missense	distal	-6	no	11.036	10.270	EPSD;PhosphoSitePlus	COSMIC	5.915	Down-regulation
CMGC_MAPK_p38_MAPK14_ST	Q9BUB5	MKNK1	Q16539	MAPK14	T255	T249P	249	Missense	distal	-6	no	10.107	9.773	PhosphoSitePlus;EPSD	COSMIC	5.915	Down-regulation
CMGC_MAPK_p38_MAPK14_ST	Q9BUB5	MKNK1	Q16539	MAPK14	T255	G258D	258	Missense	distal	3	no	10.107	10.117	PhosphoSitePlus;EPSD	COSMIC	5.915	Up-regulation
CMGC_MAPK_p38_MAPK14_ST	Q9BUB5	MKNK1	Q16539	MAPK14	T255	T249I	249	Missense	distal	-6	no	10.107	9.085	PhosphoSitePlus;EPSD	COSMIC	5.915	Down-regulation
CMGC_MAPK_p38_MAPK14_ST	Q9BUB5	MKNK1	Q16539	MAPK14	T255	T254S	254	Missense	proximal	-1	no	10.107	9.991	PhosphoSitePlus;EPSD	COSMIC	5.915	Down-regulation
CMGC_MAPK_p38_MAPK14_ST	Q9BUB5	MKNK1	Q16539	MAPK14	T385	P384H	384	Missense	proximal	-1	no	8.427	8.382	EPSD	COSMIC	5.915	Down-regulation
CMGC_MAPK_p38_MAPK14_ST	Q9BUB5	MKNK1	Q16539	MAPK14	T385	T385P	385	Missense	central	0	yes	8.427	0.000	EPSD	COSMIC	5.915	Loss
CMGC_MAPK_p38_MAPK14_ST	Q9BUB5	MKNK1	Q16539	MAPK14	T385	P386L	386	Missense	proximal	1	no	8.427	0.376	EPSD	COSMIC;GDSC;CCLE	5.915	Loss
CMGC_MAPK_p38_MAPK14_ST	Q9BUB5	MKNK1	Q16539	MAPK14	T385	L383P	383	Missense	proximal	-2	no	8.427	9.807	EPSD	COSMIC	5.915	Up-regulation
CMGC_MAPK_p38_MAPK14_ST	Q9BUB5	MKNK1	Q16539	MAPK14	T385	L383F	383	Missense	proximal	-2	no	8.427	8.594	EPSD	COSMIC	5.915	Up-regulation
CMGC_MAPK_p38_MAPK14_ST	Q9BUB5	MKNK1	Q16539	MAPK14	T385	P384L	384	Missense	proximal	-1	no	8.427	8.612	EPSD	COSMIC	5.915	Up-regulation
CMGC_MAPK_p38_MAPK14_ST	Q9BUB5	MKNK1	Q16539	MAPK14	T385	K381E	381	Missense	distal	-4	no	8.427	8.201	EPSD	COSMIC;GDSC;CCLE	5.915	Down-regulation
CMGC_MAPK_p38_MAPK14_ST	Q9BUB5	MKNK1	Q16539	MAPK14	S413	A407T	407	Missense	distal	-6	no	5.745	6.015	EPSD	COSMIC	5.915	Gain
CMGC_MAPK_p38_MAPK14_ST	Q9BUB5	MKNK1	Q16539	MAPK14	S437	L431P	431	Missense	distal	-6	no	10.642	11.255	EPSD	COSMIC	5.915	Up-regulation
CMGC_MAPK_p38_MAPK14_ST	Q9BUB5	MKNK1	Q16539	MAPK14	S437	K435N	435	Missense	proximal	-2	no	10.642	10.758	EPSD	COSMIC	5.915	Up-regulation
CMGC_MAPK_p38_MAPK14_ST	Q9BUB5	MKNK1	Q16539	MAPK14	S437	C440F	440	Missense	distal	3	no	10.642	10.666	EPSD	COSMIC;GDSC;CCLE	5.915	Up-regulation
CMGC_MAPK_p38_MAPK14_ST	Q9BUB5	MKNK1	Q16539	MAPK14	S460	P461L	461	Missense	proximal	1	no	9.280	1.230	EPSD	COSMIC	5.915	Loss
CMGC_MAPK_p38_MAPK14_ST	Q9BUB5	MKNK1	Q16539	MAPK14	S460	G456V	456	Missense	distal	-4	no	9.280	9.605	EPSD	COSMIC	5.915	Up-regulation
CMGC_MAPK_p38_MAPK14_ST	Q9Y6Q9	NCOA3	Q16539	MAPK14	T24	R18C	18	Missense	distal	-6	no	10.371	9.185	EPSD	COSMIC	5.915	Down-regulation
CMGC_MAPK_p38_MAPK14_ST	Q9Y6Q9	NCOA3	Q16539	MAPK14	T24	K19R	19	Missense	distal	-5	no	10.371	10.506	EPSD	COSMIC	5.915	Up-regulation
CMGC_MAPK_p38_MAPK14_ST	Q9Y6Q9	NCOA3	Q16539	MAPK14	T24	L20W	20	Missense	distal	-4	no	10.371	10.411	EPSD	COSMIC	5.915	Up-regulation
CMGC_MAPK_p38_MAPK14_ST	Q9Y6Q9	NCOA3	Q16539	MAPK14	T203	E209K	209	Missense	distal	6	no	6.895	6.889	EPSD	COSMIC	5.915	Down-regulation
CMGC_MAPK_p38_MAPK14_ST	Q9Y6Q9	NCOA3	Q16539	MAPK14	T203	N196H	196	Missense	distal	-7	no	6.895	6.642	EPSD	COSMIC	5.915	Down-regulation
CMGC_MAPK_p38_MAPK14_ST	Q9Y6Q9	NCOA3	Q16539	MAPK14	T203	T203A	203	Missense	central	0	yes	6.895	0.000	EPSD	COSMIC	5.915	Loss
CMGC_MAPK_p38_MAPK14_ST	Q9Y6Q9	NCOA3	Q16539	MAPK14	T203	E209D	209	Missense	distal	6	no	6.895	6.794	EPSD	COSMIC	5.915	Down-regulation
CMGC_MAPK_p38_MAPK14_ST	Q9Y6Q9	NCOA3	Q16539	MAPK14	T203	H205R	205	Missense	proximal	2	no	6.895	7.278	EPSD	COSMIC	5.915	Up-regulation
CMGC_MAPK_p38_MAPK14_ST	Q9Y6Q9	NCOA3	Q16539	MAPK14	T203	C197R	197	Missense	distal	-6	no	6.895	8.081	EPSD	COSMIC	5.915	Up-regulation
CMGC_MAPK_p38_MAPK14_ST	Q9Y6Q9	NCOA3	Q16539	MAPK14	S214	R218C	218	Missense	distal	4	no	11.788	11.353	EPSD	COSMIC	5.915	Down-regulation
CMGC_MAPK_p38_MAPK14_ST	Q9Y6Q9	NCOA3	Q16539	MAPK14	S214	E209K	209	Missense	distal	-5	no	11.788	12.122	EPSD	COSMIC	5.915	Up-regulation
CMGC_MAPK_p38_MAPK14_ST	Q9Y6Q9	NCOA3	Q16539	MAPK14	S214	R218H	218	Missense	distal	4	no	11.788	11.395	EPSD	COSMIC	5.915	Down-regulation
CMGC_MAPK_p38_MAPK14_ST	Q9Y6Q9	NCOA3	Q16539	MAPK14	S214	M217I	217	Missense	distal	3	no	11.788	11.846	EPSD	COSMIC	5.915	Up-regulation
CMGC_MAPK_p38_MAPK14_ST	Q9Y6Q9	NCOA3	Q16539	MAPK14	S214	Y221H	221	Missense	distal	7	no	11.788	11.246	EPSD	COSMIC	5.915	Down-regulation
CMGC_MAPK_p38_MAPK14_ST	Q9Y6Q9	NCOA3	Q16539	MAPK14	S214	A213T	213	Missense	proximal	-1	no	11.788	11.844	EPSD	COSMIC;GDSC	5.915	Up-regulation
CMGC_MAPK_p38_MAPK14_ST	Q9Y6Q9	NCOA3	Q16539	MAPK14	S214	E209D	209	Missense	distal	-5	no	11.788	12.662	EPSD	COSMIC	5.915	Up-regulation
CMGC_MAPK_p38_MAPK14_ST	Q9Y6Q9	NCOA3	Q16539	MAPK14	S450	S452P	452	Missense	proximal	2	no	9.960	9.583	EPSD	COSMIC;GDSC;CCLE	5.915	Down-regulation
CMGC_MAPK_p38_MAPK14_ST	Q9Y6Q9	NCOA3	Q16539	MAPK14	S465	N462S	462	Missense	distal	-3	no	9.402	10.549	EPSD	COSMIC	5.915	Up-regulation
CMGC_MAPK_p38_MAPK14_ST	Q9Y6Q9	NCOA3	Q16539	MAPK14	S465	G460E	460	Missense	distal	-5	no	9.402	8.770	EPSD	COSMIC	5.915	Down-regulation
CMGC_MAPK_p38_MAPK14_ST	Q9Y6Q9	NCOA3	Q16539	MAPK14	S465	G469W	469	Missense	distal	4	no	9.402	7.643	EPSD	COSMIC	5.915	Down-regulation
CMGC_MAPK_p38_MAPK14_ST	Q9Y6Q9	NCOA3	Q16539	MAPK14	S465	P471H	471	Missense	distal	6	no	9.402	9.283	EPSD	COSMIC	5.915	Down-regulation
CMGC_MAPK_p38_MAPK14_ST	Q9Y6Q9	NCOA3	Q16539	MAPK14	S470	G469W	469	Missense	proximal	-1	no	8.685	8.652	EPSD	COSMIC	5.915	Down-regulation
CMGC_MAPK_p38_MAPK14_ST	Q9Y6Q9	NCOA3	Q16539	MAPK14	S470	P471H	471	Missense	proximal	1	no	8.685	-4.969	EPSD	COSMIC	5.915	Loss
CMGC_MAPK_p38_MAPK14_ST	Q9Y6Q9	NCOA3	Q16539	MAPK14	S505	P499L	499	Missense	distal	-6	no	11.775	11.162	EPSD;PhosphoSitePlus	COSMIC;GDSC;CCLE	5.915	Down-regulation
CMGC_MAPK_p38_MAPK14_ST	Q9Y6Q9	NCOA3	Q16539	MAPK14	S505	V503M	503	Missense	proximal	-2	no	11.775	12.040	EPSD;PhosphoSitePlus	COSMIC	5.915	Up-regulation
CMGC_MAPK_p38_MAPK14_ST	Q9Y6Q9	NCOA3	Q16539	MAPK14	S505	H504Y	504	Missense	proximal	-1	no	11.775	11.728	EPSD;PhosphoSitePlus	COSMIC	5.915	Down-regulation
CMGC_MAPK_p38_MAPK14_ST	Q9Y6Q9	NCOA3	Q16539	MAPK14	S505	A508T	508	Missense	distal	3	no	11.775	11.774	EPSD;PhosphoSitePlus	COSMIC;GDSC;CCLE	5.915	Down-regulation
CMGC_MAPK_p38_MAPK14_ST	Q9Y6Q9	NCOA3	Q16539	MAPK14	S543	K547T	547	Missense	distal	4	no	13.250	12.955	EPSD;PhosphoSitePlus	COSMIC	5.915	Down-regulation
CMGC_MAPK_p38_MAPK14_ST	Q9Y6Q9	NCOA3	Q16539	MAPK14	S543	S543P	543	Missense	central	0	yes	13.250	0.000	EPSD;PhosphoSitePlus	COSMIC	5.915	Loss
CMGC_MAPK_p38_MAPK14_ST	Q9Y6Q9	NCOA3	Q16539	MAPK14	S551	K547T	547	Missense	distal	-4	no	9.578	9.928	EPSD	COSMIC	5.915	Up-regulation
CMGC_MAPK_p38_MAPK14_ST	Q9Y6Q9	NCOA3	Q16539	MAPK14	S551	D549N	549	Missense	proximal	-2	no	9.578	10.092	EPSD	COSMIC	5.915	Up-regulation
CMGC_MAPK_p38_MAPK14_ST	Q9Y6Q9	NCOA3	Q16539	MAPK14	S569	D576N	576	Missense	distal	7	no	9.494	9.172	EPSD	COSMIC	5.915	Down-regulation
CMGC_MAPK_p38_MAPK14_ST	Q9Y6Q9	NCOA3	Q16539	MAPK14	S569	D566Y	566	Missense	distal	-3	no	9.494	9.588	EPSD	COSMIC	5.915	Up-regulation
CMGC_MAPK_p38_MAPK14_ST	Q9Y6Q9	NCOA3	Q16539	MAPK14	S569	N564S	564	Missense	distal	-5	no	9.494	9.030	EPSD	COSMIC	5.915	Down-regulation
CMGC_MAPK_p38_MAPK14_ST	Q9Y6Q9	NCOA3	Q16539	MAPK14	S635	R632W	632	Missense	distal	-3	no	6.837	4.480	EPSD	COSMIC	5.915	Loss
CMGC_MAPK_p38_MAPK14_ST	Q9Y6Q9	NCOA3	Q16539	MAPK14	S635	S636F	636	Missense	proximal	1	no	6.837	8.117	EPSD	COSMIC	5.915	Up-regulation
CMGC_MAPK_p38_MAPK14_ST	Q9Y6Q9	NCOA3	Q16539	MAPK14	S640	S636F	636	Missense	distal	-4	no	11.405	12.110	EPSD	COSMIC	5.915	Up-regulation
CMGC_MAPK_p38_MAPK14_ST	Q9Y6Q9	NCOA3	Q16539	MAPK14	S655	E648K	648	Missense	distal	-7	no	11.209	11.155	EPSD	COSMIC	5.915	Down-regulation
CMGC_MAPK_p38_MAPK14_ST	Q9Y6Q9	NCOA3	Q16539	MAPK14	S694	I701L	701	Missense	distal	7	no	10.428	10.776	EPSD	COSMIC	5.915	Up-regulation
CMGC_MAPK_p38_MAPK14_ST	Q9Y6Q9	NCOA3	Q16539	MAPK14	S694	A696S	696	Missense	proximal	2	no	10.428	10.692	EPSD	COSMIC	5.915	Up-regulation
CMGC_MAPK_p38_MAPK14_ST	Q9Y6Q9	NCOA3	Q16539	MAPK14	S694	L689P	689	Missense	distal	-5	no	10.428	10.147	EPSD	COSMIC	5.915	Down-regulation
CMGC_MAPK_p38_MAPK14_ST	Q9Y6Q9	NCOA3	Q16539	MAPK14	S694	L688V	688	Missense	distal	-6	no	10.428	10.617	EPSD	COSMIC	5.915	Up-regulation
CMGC_MAPK_p38_MAPK14_ST	Q9Y6Q9	NCOA3	Q16539	MAPK14	T702	I701L	701	Missense	proximal	-1	no	6.084	6.385	EPSD	COSMIC	5.915	Up-regulation
CMGC_MAPK_p38_MAPK14_ST	Q9Y6Q9	NCOA3	Q16539	MAPK14	T702	K708T	708	Missense	distal	6	no	6.084	6.048	EPSD	COSMIC	5.915	Down-regulation
CMGC_MAPK_p38_MAPK14_ST	Q9Y6Q9	NCOA3	Q16539	MAPK14	T702	A696S	696	Missense	distal	-6	no	6.084	6.627	EPSD	COSMIC	5.915	Up-regulation
CMGC_MAPK_p38_MAPK14_ST	Q9Y6Q9	NCOA3	Q16539	MAPK14	S728	Q726H	726	Missense	proximal	-2	no	12.582	11.331	EPSD	COSMIC	5.915	Down-regulation
CMGC_MAPK_p38_MAPK14_ST	Q9Y6Q9	NCOA3	Q16539	MAPK14	S776	P783L	783	Missense	distal	7	no	6.180	6.017	EPSD	COSMIC	5.915	Down-regulation
CMGC_MAPK_p38_MAPK14_ST	Q9Y6Q9	NCOA3	Q16539	MAPK14	S778	I785S	785	Missense	distal	7	no	5.580	6.313	EPSD	COSMIC	5.915	Gain
CMGC_MAPK_p38_MAPK14_ST	Q9Y6Q9	NCOA3	Q16539	MAPK14	S860	S867C	867	Missense	distal	7	no	14.509	13.944	EPSD;PhosphoSitePlus	COSMIC	5.915	Down-regulation
CMGC_MAPK_p38_MAPK14_ST	Q9Y6Q9	NCOA3	Q16539	MAPK14	S860	S863F	863	Missense	distal	3	no	14.509	14.617	EPSD;PhosphoSitePlus	COSMIC	5.915	Up-regulation
CMGC_MAPK_p38_MAPK14_ST	Q9Y6Q9	NCOA3	Q16539	MAPK14	S860	G865D	865	Missense	distal	5	no	14.509	14.220	EPSD;PhosphoSitePlus	COSMIC	5.915	Down-regulation
CMGC_MAPK_p38_MAPK14_ST	Q9Y6Q9	NCOA3	Q16539	MAPK14	S860	S857C	857	Missense	distal	-3	no	14.509	12.826	EPSD;PhosphoSitePlus	COSMIC	5.915	Down-regulation
CMGC_MAPK_p38_MAPK14_ST	Q9Y6Q9	NCOA3	Q16539	MAPK14	S867	S867C	867	Missense	central	0	yes	10.395	0.000	PhosphoSitePlus;EPSD	COSMIC	5.915	Loss
CMGC_MAPK_p38_MAPK14_ST	Q9Y6Q9	NCOA3	Q16539	MAPK14	S867	S863F	863	Missense	distal	-4	no	10.395	11.099	PhosphoSitePlus;EPSD	COSMIC	5.915	Up-regulation
CMGC_MAPK_p38_MAPK14_ST	Q9Y6Q9	NCOA3	Q16539	MAPK14	S867	G865D	865	Missense	proximal	-2	no	10.395	9.644	PhosphoSitePlus;EPSD	COSMIC	5.915	Down-regulation
CMGC_MAPK_p38_MAPK14_ST	Q9Y6Q9	NCOA3	Q16539	MAPK14	T914	D919V	919	Missense	distal	5	no	10.161	10.048	EPSD	COSMIC	5.915	Down-regulation
CMGC_MAPK_p38_MAPK14_ST	Q9Y6Q9	NCOA3	Q16539	MAPK14	T914	W920R	920	Missense	distal	6	no	10.161	10.424	EPSD	COSMIC	5.915	Up-regulation
CMGC_MAPK_p38_MAPK14_ST	Q9Y6Q9	NCOA3	Q16539	MAPK14	S1330	S1330G	1330	Missense	central	0	yes	12.439	0.000	EPSD	COSMIC	5.915	Loss
CMGC_MAPK_p38_MAPK14_ST	Q9Y6Q9	NCOA3	Q16539	MAPK14	S1330	P1331L	1331	Missense	proximal	1	no	12.439	4.389	EPSD	COSMIC	5.915	Loss
CMGC_MAPK_p38_MAPK14_ST	P53667	LIMK1	Q16539	MAPK14	S154	G156A	156	Missense	proximal	2	no	8.619	8.584	EPSD	COSMIC	5.915	Down-regulation
CMGC_MAPK_p38_MAPK14_ST	P53667	LIMK1	Q16539	MAPK14	S154	P155S	155	Missense	proximal	1	no	8.619	1.335	EPSD	COSMIC	5.915	Loss
CMGC_MAPK_p38_MAPK14_ST	P53667	LIMK1	Q16539	MAPK14	S154	P152H	152	Missense	proximal	-2	no	8.619	6.352	EPSD	COSMIC	5.915	Down-regulation
CMGC_MAPK_p38_MAPK14_ST	P53667	LIMK1	Q16539	MAPK14	S154	E148K	148	Missense	distal	-6	no	8.619	8.204	EPSD	COSMIC	5.915	Down-regulation
CMGC_MAPK_p38_MAPK14_ST	P53667	LIMK1	Q16539	MAPK14	S154	S154F	154	Missense	central	0	yes	8.619	0.000	EPSD	COSMIC	5.915	Loss
CMGC_MAPK_p38_MAPK14_ST	P53667	LIMK1	Q16539	MAPK14	S210	G207D	207	Missense	distal	-3	no	8.453	8.402	EPSD	COSMIC	5.915	Down-regulation
CMGC_MAPK_p38_MAPK14_ST	P53667	LIMK1	Q16539	MAPK14	S210	P206Q	206	Missense	distal	-4	no	8.453	8.744	EPSD	COSMIC	5.915	Up-regulation
CMGC_MAPK_p38_MAPK14_ST	P53667	LIMK1	Q16539	MAPK14	S210	M209V	209	Missense	proximal	-1	no	8.453	8.545	EPSD	COSMIC	5.915	Up-regulation
CMGC_MAPK_p38_MAPK14_ST	P53667	LIMK1	Q16539	MAPK14	S210	S216T	216	Missense	distal	6	no	8.453	8.490	EPSD	COSMIC	5.915	Up-regulation
CMGC_MAPK_p38_MAPK14_ST	P53667	LIMK1	Q16539	MAPK14	S210	G207R	207	Missense	distal	-3	no	8.453	9.903	EPSD	COSMIC	5.915	Up-regulation
CMGC_MAPK_p38_MAPK14_ST	P53667	LIMK1	Q16539	MAPK14	T229	L236M	236	Missense	distal	7	no	7.329	7.583	EPSD	COSMIC	5.915	Up-regulation
CMGC_MAPK_p38_MAPK14_ST	P53667	LIMK1	Q16539	MAPK14	T270	G265R	265	Missense	distal	-5	no	6.217	6.055	EPSD	COSMIC	5.915	Down-regulation
CMGC_MAPK_p38_MAPK14_ST	P53667	LIMK1	Q16539	MAPK14	T270	A277T	277	Missense	distal	7	no	6.217	5.874	EPSD	COSMIC	5.915	Loss
CMGC_MAPK_p38_MAPK14_ST	P53667	LIMK1	Q16539	MAPK14	T270	P268T	268	Missense	proximal	-2	no	6.217	5.498	EPSD	COSMIC	5.915	Loss
CMGC_MAPK_p38_MAPK14_ST	P53667	LIMK1	Q16539	MAPK14	T270	G265V	265	Missense	distal	-5	no	6.217	6.440	EPSD	COSMIC	5.915	Up-regulation
CMGC_MAPK_p38_MAPK14_ST	P53667	LIMK1	Q16539	MAPK14	S271	G265R	265	Missense	distal	-6	no	12.125	12.499	EPSD	COSMIC	5.915	Up-regulation
CMGC_MAPK_p38_MAPK14_ST	P53667	LIMK1	Q16539	MAPK14	S271	A277T	277	Missense	distal	6	no	12.125	12.108	EPSD	COSMIC	5.915	Down-regulation
CMGC_MAPK_p38_MAPK14_ST	P53667	LIMK1	Q16539	MAPK14	S271	P276Q	276	Missense	distal	5	no	12.125	11.916	EPSD	COSMIC	5.915	Down-regulation
CMGC_MAPK_p38_MAPK14_ST	P53667	LIMK1	Q16539	MAPK14	S271	P268T	268	Missense	distal	-3	no	12.125	12.571	EPSD	COSMIC	5.915	Up-regulation
CMGC_MAPK_p38_MAPK14_ST	P53667	LIMK1	Q16539	MAPK14	S271	G265V	265	Missense	distal	-6	no	12.125	11.575	EPSD	COSMIC	5.915	Down-regulation
CMGC_MAPK_p38_MAPK14_ST	P53667	LIMK1	Q16539	MAPK14	S275	S281N	281	Missense	distal	6	no	10.919	10.898	EPSD	COSMIC;GDSC;CCLE	5.915	Down-regulation
CMGC_MAPK_p38_MAPK14_ST	P53667	LIMK1	Q16539	MAPK14	S275	A277T	277	Missense	proximal	2	no	10.919	10.947	EPSD	COSMIC	5.915	Up-regulation
CMGC_MAPK_p38_MAPK14_ST	P53667	LIMK1	Q16539	MAPK14	S275	P276Q	276	Missense	proximal	1	no	10.919	3.710	EPSD	COSMIC	5.915	Loss
CMGC_MAPK_p38_MAPK14_ST	P53667	LIMK1	Q16539	MAPK14	S275	P268T	268	Missense	distal	-7	no	10.919	10.936	EPSD	COSMIC	5.915	Up-regulation
CMGC_MAPK_p38_MAPK14_ST	P53667	LIMK1	Q16539	MAPK14	T279	S286I	286	Missense	distal	7	no	12.751	12.019	EPSD	COSMIC	5.915	Down-regulation
CMGC_MAPK_p38_MAPK14_ST	P53667	LIMK1	Q16539	MAPK14	T279	S286R	286	Missense	distal	7	no	12.751	12.786	EPSD	COSMIC	5.915	Up-regulation
CMGC_MAPK_p38_MAPK14_ST	P53667	LIMK1	Q16539	MAPK14	T279	S281N	281	Missense	proximal	2	no	12.751	12.495	EPSD	COSMIC;GDSC;CCLE	5.915	Down-regulation
CMGC_MAPK_p38_MAPK14_ST	P53667	LIMK1	Q16539	MAPK14	T279	A277T	277	Missense	proximal	-2	no	12.751	12.694	EPSD	COSMIC	5.915	Down-regulation
CMGC_MAPK_p38_MAPK14_ST	P53667	LIMK1	Q16539	MAPK14	T279	P276Q	276	Missense	distal	-3	no	12.751	12.248	EPSD	COSMIC	5.915	Down-regulation
CMGC_MAPK_p38_MAPK14_ST	P53667	LIMK1	Q16539	MAPK14	S281	S286I	286	Missense	distal	5	no	7.526	6.433	EPSD	COSMIC	5.915	Down-regulation
CMGC_MAPK_p38_MAPK14_ST	P53667	LIMK1	Q16539	MAPK14	S281	S286R	286	Missense	distal	5	no	7.526	7.216	EPSD	COSMIC	5.915	Down-regulation
CMGC_MAPK_p38_MAPK14_ST	P53667	LIMK1	Q16539	MAPK14	S281	S281N	281	Missense	central	0	yes	7.526	0.000	EPSD	COSMIC;GDSC;CCLE	5.915	Loss
CMGC_MAPK_p38_MAPK14_ST	P53667	LIMK1	Q16539	MAPK14	S281	A277T	277	Missense	distal	-4	no	7.526	7.763	EPSD	COSMIC	5.915	Up-regulation
CMGC_MAPK_p38_MAPK14_ST	P53667	LIMK1	Q16539	MAPK14	S281	P276Q	276	Missense	distal	-5	no	7.526	7.254	EPSD	COSMIC	5.915	Down-regulation
CMGC_MAPK_p38_MAPK14_ST	P53667	LIMK1	Q16539	MAPK14	S287	S286I	286	Missense	proximal	-1	no	5.939	5.917	EPSD	COSMIC	5.915	Down-regulation
CMGC_MAPK_p38_MAPK14_ST	P53667	LIMK1	Q16539	MAPK14	S287	S286R	286	Missense	proximal	-1	no	5.939	5.832	EPSD	COSMIC	5.915	Loss
CMGC_MAPK_p38_MAPK14_ST	P53667	LIMK1	Q16539	MAPK14	S287	S281N	281	Missense	distal	-6	no	5.939	5.516	EPSD	COSMIC;GDSC;CCLE	5.915	Loss
CMGC_MAPK_p38_MAPK14_ST	P53667	LIMK1	Q16539	MAPK14	S302	R295W	295	Missense	distal	-7	no	8.829	8.090	EPSD	COSMIC	5.915	Down-regulation
CMGC_MAPK_p38_MAPK14_ST	P53667	LIMK1	Q16539	MAPK14	S313	R320L	320	Missense	distal	7	no	5.975	5.555	EPSD	COSMIC;GDSC;CCLE	5.915	Loss
CMGC_MAPK_p38_MAPK14_ST	P53667	LIMK1	Q16539	MAPK14	S313	R320H	320	Missense	distal	7	no	5.975	5.441	EPSD	COSMIC	5.915	Loss
CMGC_MAPK_p38_MAPK14_ST	Q15672	TWIST1	Q16539	MAPK14	S8	S11L	11	Missense	distal	3	no	9.523	9.597	EPSD	COSMIC	5.915	Up-regulation
CMGC_MAPK_p38_MAPK14_ST	Q15672	TWIST1	Q16539	MAPK14	S11	S11L	11	Missense	central	0	yes	12.442	0.000	EPSD	COSMIC	5.915	Loss
CMGC_MAPK_p38_MAPK14_ST	Q15672	TWIST1	Q16539	MAPK14	S68	P66A	66	Missense	proximal	-2	no	13.899	13.236	PhosphoSitePlus	COSMIC	5.915	Down-regulation
CMGC_MAPK_p38_MAPK14_ST	Q15672	TWIST1	Q16539	MAPK14	S99	E104K	104	Missense	distal	5	no	12.310	11.743	EPSD	COSMIC	5.915	Down-regulation
CMGC_MAPK_p38_MAPK14_ST	Q15672	TWIST1	Q16539	MAPK14	S99	P100S	100	Missense	proximal	1	no	12.310	5.026	EPSD	COSMIC	5.915	Loss
CMGC_MAPK_p38_MAPK14_ST	P49137	MAPKAPK2	Q16539	MAPK14	T25	P26L	26	Missense	proximal	1	no	10.957	2.907	EPSD;PhosphoSitePlus	COSMIC	5.915	Loss
CMGC_MAPK_p38_MAPK14_ST	P49137	MAPKAPK2	Q16539	MAPK14	T25	L28P	28	Missense	distal	3	no	10.957	10.923	EPSD;PhosphoSitePlus	COSMIC	5.915	Down-regulation
CMGC_MAPK_p38_MAPK14_ST	P49137	MAPKAPK2	Q16539	MAPK14	T222	P223L	223	Missense	proximal	1	no	13.944	5.893	PhosphoSitePlus;EPSD	COSMIC	5.915	Loss
CMGC_MAPK_p38_MAPK14_ST	P49137	MAPKAPK2	Q16539	MAPK14	T226	P223L	223	Missense	distal	-3	no	9.442	8.475	EPSD	COSMIC	5.915	Down-regulation
CMGC_MAPK_p38_MAPK14_ST	P49137	MAPKAPK2	Q16539	MAPK14	S272	G268S	268	Missense	distal	-4	no	10.608	10.611	EPSD;PhosphoSitePlus	COSMIC	5.915	Up-regulation
CMGC_MAPK_p38_MAPK14_ST	P49137	MAPKAPK2	Q16539	MAPK14	S272	R278H	278	Missense	distal	6	no	10.608	10.501	EPSD;PhosphoSitePlus	COSMIC	5.915	Down-regulation
CMGC_MAPK_p38_MAPK14_ST	P49137	MAPKAPK2	Q16539	MAPK14	T334	R340Q	340	Missense	distal	6	no	11.967	11.979	EPSD;PhosphoSitePlus	COSMIC	5.915	Up-regulation
CMGC_MAPK_p38_MAPK14_ST	P49137	MAPKAPK2	Q16539	MAPK14	T334	P335S	335	Missense	proximal	1	no	11.967	4.683	EPSD;PhosphoSitePlus	COSMIC	5.915	Loss
CMGC_MAPK_p38_MAPK14_ST	P49137	MAPKAPK2	Q16539	MAPK14	T334	T329I	329	Missense	distal	-5	no	11.967	11.925	EPSD;PhosphoSitePlus	COSMIC	5.915	Down-regulation
CMGC_MAPK_p38_MAPK14_ST	P52945	PDX1	Q16539	MAPK14	S31	P33L	33	Missense	proximal	2	no	9.809	9.696	EPSD	COSMIC;CCLE	5.915	Down-regulation
CMGC_MAPK_p38_MAPK14_ST	P52945	PDX1	Q16539	MAPK14	S31	P33T	33	Missense	proximal	2	no	9.809	9.950	EPSD	COSMIC	5.915	Up-regulation
CMGC_MAPK_p38_MAPK14_ST	P52945	PDX1	Q16539	MAPK14	S31	P33H	33	Missense	proximal	2	no	9.809	9.657	EPSD	COSMIC	5.915	Down-regulation
CMGC_MAPK_p38_MAPK14_ST	P52945	PDX1	Q16539	MAPK14	S266	S266R	266	Missense	central	0	yes	6.156	0.000	EPSD	COSMIC;CCLE	5.915	Loss
CMGC_MAPK_p38_MAPK14_ST	P52945	PDX1	Q16539	MAPK14	S268	S266R	266	Missense	proximal	-2	no	9.493	9.293	EPSD	COSMIC;CCLE	5.915	Down-regulation
CMGC_MAPK_p38_MAPK14_ST	P19525	EIF2AK2	Q16539	MAPK14	S181	S178F	178	Missense	distal	-3	no	6.762	4.055	EPSD	COSMIC;CCLE	5.915	Loss
CMGC_MAPK_p38_MAPK14_ST	P19525	EIF2AK2	Q16539	MAPK14	S181	D175Y	175	Missense	distal	-6	no	6.762	6.745	EPSD	COSMIC	5.915	Down-regulation
CMGC_MAPK_p38_MAPK14_ST	P19525	EIF2AK2	Q16539	MAPK14	S181	S179F	179	Missense	proximal	-2	no	6.762	6.038	EPSD	COSMIC	5.915	Down-regulation
CMGC_MAPK_p38_MAPK14_ST	P19525	EIF2AK2	Q16539	MAPK14	S181	T185M	185	Missense	distal	4	no	6.762	6.700	EPSD	COSMIC	5.915	Down-regulation
CMGC_MAPK_p38_MAPK14_ST	P19525	EIF2AK2	Q16539	MAPK14	T451	R445Q	445	Missense	distal	-6	no	6.169	5.499	PhosphoSitePlus	COSMIC	5.915	Loss
CMGC_MAPK_p38_MAPK14_ST	P19525	EIF2AK2	Q16539	MAPK14	T451	S448N	448	Missense	distal	-3	no	6.169	5.021	PhosphoSitePlus	COSMIC	5.915	Loss
CMGC_MAPK_p38_MAPK14_ST	P19525	EIF2AK2	Q16539	MAPK14	T451	K444R	444	Missense	distal	-7	no	6.169	5.903	PhosphoSitePlus	COSMIC	5.915	Loss
CMGC_MAPK_p38_MAPK14_ST	P19525	EIF2AK2	Q16539	MAPK14	S542	R548Q	548	Missense	distal	6	no	10.177	10.189	EPSD	COSMIC	5.915	Up-regulation
CMGC_MAPK_p38_MAPK14_ST	P19525	EIF2AK2	Q16539	MAPK14	S542	K540M	540	Missense	proximal	-2	no	10.177	10.657	EPSD	COSMIC	5.915	Up-regulation
CMGC_MAPK_p38_MAPK14_ST	O75582	RPS6KA5	Q16539	MAPK14	S212	F213V	213	Missense	proximal	1	no	6.531	3.256	EPSD	COSMIC	5.915	Loss
CMGC_MAPK_p38_MAPK14_ST	O75582	RPS6KA5	Q16539	MAPK14	S212	Y219C	219	Missense	distal	7	no	6.531	5.923	EPSD	COSMIC	5.915	Down-regulation
CMGC_MAPK_p38_MAPK14_ST	O75582	RPS6KA5	Q16539	MAPK14	S212	E206K	206	Missense	distal	-6	no	6.531	6.116	EPSD	COSMIC	5.915	Down-regulation
CMGC_MAPK_p38_MAPK14_ST	O75582	RPS6KA5	Q16539	MAPK14	S253	G251R	251	Missense	proximal	-2	no	11.620	11.870	EPSD	COSMIC	5.915	Up-regulation
CMGC_MAPK_p38_MAPK14_ST	O75582	RPS6KA5	Q16539	MAPK14	S253	E260K	260	Missense	distal	7	no	11.620	10.913	EPSD	COSMIC	5.915	Down-regulation
CMGC_MAPK_p38_MAPK14_ST	O75582	RPS6KA5	Q16539	MAPK14	T353	P357S	357	Missense	distal	4	no	6.747	7.186	EPSD	COSMIC	5.915	Up-regulation
CMGC_MAPK_p38_MAPK14_ST	O75582	RPS6KA5	Q16539	MAPK14	T353	E354K	354	Missense	proximal	1	no	6.747	5.499	EPSD	COSMIC	5.915	Loss
CMGC_MAPK_p38_MAPK14_ST	O75582	RPS6KA5	Q16539	MAPK14	S360	A362T	362	Missense	proximal	2	no	11.097	11.125	PhosphoSitePlus;EPSD	COSMIC	5.915	Up-regulation
CMGC_MAPK_p38_MAPK14_ST	O75582	RPS6KA5	Q16539	MAPK14	S360	P357S	357	Missense	distal	-3	no	11.097	11.860	PhosphoSitePlus;EPSD	COSMIC	5.915	Up-regulation
CMGC_MAPK_p38_MAPK14_ST	O75582	RPS6KA5	Q16539	MAPK14	S360	E354K	354	Missense	distal	-6	no	11.097	10.682	PhosphoSitePlus;EPSD	COSMIC	5.915	Down-regulation
CMGC_MAPK_p38_MAPK14_ST	O75582	RPS6KA5	Q16539	MAPK14	T581	P582L	582	Missense	proximal	1	no	10.790	2.739	EPSD;PhosphoSitePlus	COSMIC	5.915	Loss
CMGC_MAPK_p38_MAPK14_ST	O75582	RPS6KA5	Q16539	MAPK14	T581	P578H	578	Missense	distal	-3	no	10.790	10.312	EPSD;PhosphoSitePlus	COSMIC	5.915	Down-regulation
CMGC_MAPK_p38_MAPK14_ST	O75582	RPS6KA5	Q16539	MAPK14	T581	P578S	578	Missense	distal	-3	no	10.790	11.553	EPSD;PhosphoSitePlus	COSMIC	5.915	Up-regulation
CMGC_MAPK_p38_MAPK14_ST	O75582	RPS6KA5	Q16539	MAPK14	S691	Q692R	692	Missense	proximal	1	no	6.290	5.563	EPSD	COSMIC	5.915	Loss
CMGC_MAPK_p38_MAPK14_ST	O75582	RPS6KA5	Q16539	MAPK14	S691	N684S	684	Missense	distal	-7	no	6.290	6.501	EPSD	COSMIC	5.915	Up-regulation
CMGC_MAPK_p38_MAPK14_ST	O75582	RPS6KA5	Q16539	MAPK14	S695	Q692R	692	Missense	distal	-3	no	4.289	6.068	EPSD	COSMIC	5.915	Gain
CMGC_MAPK_p38_MAPK14_ST	O75582	RPS6KA5	Q16539	MAPK14	T700	M699T	699	Missense	proximal	-1	no	11.163	11.156	EPSD	COSMIC	5.915	Down-regulation
CMGC_MAPK_p38_MAPK14_ST	O75582	RPS6KA5	Q16539	MAPK14	S750	T755M	755	Missense	distal	5	no	6.200	5.887	EPSD	COSMIC;GDSC;CCLE	5.915	Loss
CMGC_MAPK_p38_MAPK14_ST	O75582	RPS6KA5	Q16539	MAPK14	S750	R756C	756	Missense	distal	6	no	6.200	5.925	EPSD	COSMIC	5.915	Down-regulation
CMGC_MAPK_p38_MAPK14_ST	O75582	RPS6KA5	Q16539	MAPK14	S750	E754D	754	Missense	distal	4	no	6.200	4.530	EPSD	COSMIC	5.915	Loss
CMGC_MAPK_p38_MAPK14_ST	O75582	RPS6KA5	Q16539	MAPK14	S750	E754K	754	Missense	distal	4	no	6.200	5.734	EPSD	COSMIC	5.915	Loss
CMGC_MAPK_p38_MAPK14_ST	O75582	RPS6KA5	Q16539	MAPK14	S759	E761K	761	Missense	proximal	2	no	7.234	6.920	EPSD	COSMIC	5.915	Down-regulation
CMGC_MAPK_p38_MAPK14_ST	O75582	RPS6KA5	Q16539	MAPK14	S759	T755M	755	Missense	distal	-4	no	7.234	7.028	EPSD	COSMIC;GDSC;CCLE	5.915	Down-regulation
CMGC_MAPK_p38_MAPK14_ST	O75582	RPS6KA5	Q16539	MAPK14	S759	R756C	756	Missense	distal	-3	no	7.234	5.039	EPSD	COSMIC	5.915	Loss
CMGC_MAPK_p38_MAPK14_ST	O75582	RPS6KA5	Q16539	MAPK14	S759	E754D	754	Missense	distal	-5	no	7.234	8.109	EPSD	COSMIC	5.915	Up-regulation
CMGC_MAPK_p38_MAPK14_ST	O75582	RPS6KA5	Q16539	MAPK14	S759	S766P	766	Missense	distal	7	no	7.234	7.013	EPSD	COSMIC	5.915	Down-regulation
CMGC_MAPK_p38_MAPK14_ST	O75582	RPS6KA5	Q16539	MAPK14	S759	E754K	754	Missense	distal	-5	no	7.234	7.569	EPSD	COSMIC	5.915	Up-regulation
CMGC_MAPK_p38_MAPK14_ST	P21397	MAOA	Q16539	MAPK14	S209	G202R	202	Missense	distal	-7	no	5.949	5.848	PhosphoSitePlus	COSMIC	5.915	Loss
CMGC_MAPK_p38_MAPK14_ST	P21397	MAOA	Q16539	MAPK14	S209	R206Q	206	Missense	distal	-3	no	5.949	4.170	PhosphoSitePlus	COSMIC	5.915	Loss
CMGC_MAPK_p38_MAPK14_ST	P21397	MAOA	Q16539	MAPK14	S209	Q215H	215	Missense	distal	6	no	5.949	5.830	PhosphoSitePlus	COSMIC	5.915	Loss
CMGC_MAPK_p38_MAPK14_ST	P43403	ZAP70	Q16539	MAPK14	S88	G93W	93	Missense	distal	5	no	6.932	5.983	EPSD	COSMIC	5.915	Down-regulation
CMGC_MAPK_p38_MAPK14_ST	P43403	ZAP70	Q16539	MAPK14	S88	P91A	91	Missense	distal	3	no	6.932	6.906	EPSD	COSMIC	5.915	Down-regulation
CMGC_MAPK_p38_MAPK14_ST	P43403	ZAP70	Q16539	MAPK14	S167	T169M	169	Missense	proximal	2	no	6.251	6.232	EPSD	COSMIC	5.915	Down-regulation
CMGC_MAPK_p38_MAPK14_ST	P43403	ZAP70	Q16539	MAPK14	S167	R170H	170	Missense	distal	3	no	6.251	6.322	EPSD	COSMIC	5.915	Up-regulation
CMGC_MAPK_p38_MAPK14_ST	P43403	ZAP70	Q16539	MAPK14	S167	A173V	173	Missense	distal	6	no	6.251	5.955	EPSD	COSMIC	5.915	Down-regulation
CMGC_MAPK_p38_MAPK14_ST	P43403	ZAP70	Q16539	MAPK14	S167	A173T	173	Missense	distal	6	no	6.251	6.233	EPSD	COSMIC	5.915	Down-regulation
CMGC_MAPK_p38_MAPK14_ST	P43403	ZAP70	Q16539	MAPK14	S258	S263L	263	Missense	distal	5	no	7.695	6.748	EPSD	COSMIC	5.915	Down-regulation
CMGC_MAPK_p38_MAPK14_ST	P43403	ZAP70	Q16539	MAPK14	T293	R298C	298	Missense	distal	5	no	10.107	9.237	PhosphoSitePlus	COSMIC	5.915	Down-regulation
CMGC_MAPK_p38_MAPK14_ST	P43403	ZAP70	Q16539	MAPK14	T293	R298H	298	Missense	distal	5	no	10.107	9.413	PhosphoSitePlus	COSMIC	5.915	Down-regulation
CMGC_MAPK_p38_MAPK14_ST	P43403	ZAP70	Q16539	MAPK14	S301	P305L	305	Missense	distal	4	no	14.258	13.619	EPSD	COSMIC	5.915	Down-regulation
CMGC_MAPK_p38_MAPK14_ST	P43403	ZAP70	Q16539	MAPK14	S301	R298C	298	Missense	distal	-3	no	14.258	12.063	EPSD	COSMIC	5.915	Down-regulation
CMGC_MAPK_p38_MAPK14_ST	P43403	ZAP70	Q16539	MAPK14	S301	S301F	301	Missense	central	0	yes	14.258	0.000	EPSD	COSMIC	5.915	Loss
CMGC_MAPK_p38_MAPK14_ST	P43403	ZAP70	Q16539	MAPK14	S301	D303E	303	Missense	proximal	2	no	14.258	14.709	EPSD	COSMIC	5.915	Up-regulation
CMGC_MAPK_p38_MAPK14_ST	P43403	ZAP70	Q16539	MAPK14	S301	R298H	298	Missense	distal	-3	no	14.258	12.505	EPSD	COSMIC	5.915	Down-regulation
CMGC_MAPK_p38_MAPK14_ST	P43403	ZAP70	Q16539	MAPK14	S301	R306Q	306	Missense	distal	5	no	14.258	13.909	EPSD	COSMIC	5.915	Down-regulation
CMGC_MAPK_p38_MAPK14_ST	P43403	ZAP70	Q16539	MAPK14	S301	P307S	307	Missense	distal	6	no	14.258	14.247	EPSD	COSMIC	5.915	Down-regulation
CMGC_MAPK_p38_MAPK14_ST	P43403	ZAP70	Q16539	MAPK14	S301	P307L	307	Missense	distal	6	no	14.258	14.119	EPSD	COSMIC	5.915	Down-regulation
CMGC_MAPK_p38_MAPK14_ST	P43403	ZAP70	Q16539	MAPK14	T312	P305L	305	Missense	distal	-7	no	6.237	6.044	EPSD	COSMIC	5.915	Down-regulation
CMGC_MAPK_p38_MAPK14_ST	P43403	ZAP70	Q16539	MAPK14	T312	T312M	312	Missense	central	0	yes	6.237	0.000	EPSD	COSMIC	5.915	Loss
CMGC_MAPK_p38_MAPK14_ST	P43403	ZAP70	Q16539	MAPK14	T312	R306Q	306	Missense	distal	-6	no	6.237	5.567	EPSD	COSMIC	5.915	Loss
CMGC_MAPK_p38_MAPK14_ST	P43403	ZAP70	Q16539	MAPK14	T312	P307S	307	Missense	distal	-5	no	6.237	5.789	EPSD	COSMIC	5.915	Loss
CMGC_MAPK_p38_MAPK14_ST	P43403	ZAP70	Q16539	MAPK14	T312	P307L	307	Missense	distal	-5	no	6.237	6.518	EPSD	COSMIC	5.915	Up-regulation
CMGC_MAPK_p38_MAPK14_ST	P43403	ZAP70	Q16539	MAPK14	S317	T312M	312	Missense	distal	-5	no	10.927	10.638	EPSD	COSMIC	5.915	Down-regulation
CMGC_MAPK_p38_MAPK14_ST	P43403	ZAP70	Q16539	MAPK14	S491	A495V	495	Missense	distal	4	no	6.117	5.683	EPSD	COSMIC	5.915	Loss
CMGC_MAPK_p38_MAPK14_ST	P43403	ZAP70	Q16539	MAPK14	S491	D490N	490	Missense	proximal	-1	no	6.117	5.931	EPSD	COSMIC	5.915	Down-regulation
CMGC_MAPK_p38_MAPK14_ST	P43403	ZAP70	Q16539	MAPK14	T494	A495V	495	Missense	proximal	1	no	6.181	3.221	EPSD	COSMIC	5.915	Loss
CMGC_MAPK_p38_MAPK14_ST	P43403	ZAP70	Q16539	MAPK14	T494	D490N	490	Missense	distal	-4	no	6.181	5.761	EPSD	COSMIC	5.915	Loss
CMGC_MAPK_p38_MAPK14_ST	P43403	ZAP70	Q16539	MAPK14	T494	K500R	500	Missense	distal	6	no	6.181	6.106	EPSD	COSMIC	5.915	Down-regulation
CMGC_MAPK_p38_MAPK14_ST	P43403	ZAP70	Q16539	MAPK14	T611	P608S	608	Missense	distal	-3	no	5.462	6.226	EPSD	COSMIC	5.915	Gain
CMGC_MAPK_p38_MAPK14_ST	P35236	PTPN7	Q16539	MAPK14	T30	E28K	28	Missense	proximal	-2	no	10.964	9.933	EPSD	COSMIC	5.915	Down-regulation
CMGC_MAPK_p38_MAPK14_ST	P35236	PTPN7	Q16539	MAPK14	T30	P25S	25	Missense	distal	-5	no	10.964	10.516	EPSD	COSMIC	5.915	Down-regulation
CMGC_MAPK_p38_MAPK14_ST	P35236	PTPN7	Q16539	MAPK14	T30	T30M	30	Missense	central	0	yes	10.964	0.000	EPSD	COSMIC	5.915	Loss
CMGC_MAPK_p38_MAPK14_ST	P35236	PTPN7	Q16539	MAPK14	T66	R68Q	68	Missense	proximal	2	no	13.138	12.712	PhosphoSitePlus;EPSD	COSMIC	5.915	Down-regulation
CMGC_MAPK_p38_MAPK14_ST	P35236	PTPN7	Q16539	MAPK14	T66	P60L	60	Missense	distal	-6	no	13.138	12.525	PhosphoSitePlus;EPSD	COSMIC	5.915	Down-regulation
CMGC_MAPK_p38_MAPK14_ST	P35236	PTPN7	Q16539	MAPK14	T66	R68L	68	Missense	proximal	2	no	13.138	12.795	PhosphoSitePlus;EPSD	COSMIC	5.915	Down-regulation
CMGC_MAPK_p38_MAPK14_ST	P35236	PTPN7	Q16539	MAPK14	T66	R68P	68	Missense	proximal	2	no	13.138	12.907	PhosphoSitePlus;EPSD	COSMIC	5.915	Down-regulation
CMGC_MAPK_p38_MAPK14_ST	P35236	PTPN7	Q16539	MAPK14	T66	E69G	69	Missense	distal	3	no	13.138	13.184	PhosphoSitePlus;EPSD	COSMIC	5.915	Up-regulation
CMGC_MAPK_p38_MAPK14_ST	P35236	PTPN7	Q16539	MAPK14	S93	A86D	86	Missense	distal	-7	no	13.290	12.746	EPSD;PhosphoSitePlus	COSMIC	5.915	Down-regulation
CMGC_MAPK_p38_MAPK14_ST	P35236	PTPN7	Q16539	MAPK14	S93	R89H	89	Missense	distal	-4	no	13.290	13.501	EPSD;PhosphoSitePlus	COSMIC	5.915	Up-regulation
CMGC_MAPK_p38_MAPK14_ST	P35236	PTPN7	Q16539	MAPK14	S93	L87F	87	Missense	distal	-6	no	13.290	12.745	EPSD;PhosphoSitePlus	COSMIC	5.915	Down-regulation
CMGC_MAPK_p38_MAPK14_ST	P35236	PTPN7	Q16539	MAPK14	S93	E100Q	100	Missense	distal	7	no	13.290	12.913	EPSD;PhosphoSitePlus	COSMIC	5.915	Down-regulation
CMGC_MAPK_p38_MAPK14_ST	P27816	MAP4	Q16539	MAPK14	S14	D16V	16	Missense	proximal	2	no	13.726	13.784	EPSD	COSMIC	5.915	Up-regulation
CMGC_MAPK_p38_MAPK14_ST	P27816	MAP4	Q16539	MAPK14	T76	T76I	76	Missense	central	0	yes	11.189	0.000	EPSD	COSMIC	5.915	Loss
CMGC_MAPK_p38_MAPK14_ST	P27816	MAP4	Q16539	MAPK14	S94	T101I	101	Missense	distal	7	no	6.361	5.949	EPSD	COSMIC	5.915	Down-regulation
CMGC_MAPK_p38_MAPK14_ST	P27816	MAP4	Q16539	MAPK14	S99	T101I	101	Missense	proximal	2	no	10.831	10.588	EPSD	COSMIC	5.915	Down-regulation
CMGC_MAPK_p38_MAPK14_ST	P27816	MAP4	Q16539	MAPK14	S99	E102D	102	Missense	distal	3	no	10.831	10.887	EPSD	COSMIC	5.915	Up-regulation
CMGC_MAPK_p38_MAPK14_ST	P27816	MAP4	Q16539	MAPK14	S179	A184S	184	Missense	distal	5	no	10.825	11.464	EPSD	COSMIC	5.915	Up-regulation
CMGC_MAPK_p38_MAPK14_ST	P27816	MAP4	Q16539	MAPK14	S179	P180L	180	Missense	proximal	1	no	10.825	2.775	EPSD	COSMIC	5.915	Loss
CMGC_MAPK_p38_MAPK14_ST	P27816	MAP4	Q16539	MAPK14	S205	E211K	211	Missense	distal	6	no	10.439	10.433	EPSD	COSMIC	5.915	Down-regulation
CMGC_MAPK_p38_MAPK14_ST	P27816	MAP4	Q16539	MAPK14	S205	V209A	209	Missense	distal	4	no	10.439	10.873	EPSD	COSMIC	5.915	Up-regulation
CMGC_MAPK_p38_MAPK14_ST	P27816	MAP4	Q16539	MAPK14	S280	S280L	280	Missense	central	0	yes	9.941	0.000	EPSD	COSMIC	5.915	Loss
CMGC_MAPK_p38_MAPK14_ST	P27816	MAP4	Q16539	MAPK14	S384	D389V	389	Missense	distal	5	no	11.088	10.975	EPSD	COSMIC	5.915	Down-regulation
CMGC_MAPK_p38_MAPK14_ST	P27816	MAP4	Q16539	MAPK14	S384	T380R	380	Missense	distal	-4	no	11.088	10.821	EPSD	COSMIC	5.915	Down-regulation
CMGC_MAPK_p38_MAPK14_ST	P27816	MAP4	Q16539	MAPK14	S384	K378N	378	Missense	distal	-6	no	11.088	11.250	EPSD	COSMIC	5.915	Up-regulation
CMGC_MAPK_p38_MAPK14_ST	P27816	MAP4	Q16539	MAPK14	S507	V500G	500	Missense	distal	-7	no	11.292	11.930	EPSD	COSMIC	5.915	Up-regulation
CMGC_MAPK_p38_MAPK14_ST	P27816	MAP4	Q16539	MAPK14	S507	K504N	504	Missense	distal	-3	no	11.292	11.320	EPSD	COSMIC	5.915	Up-regulation
CMGC_MAPK_p38_MAPK14_ST	P27816	MAP4	Q16539	MAPK14	S510	K504N	504	Missense	distal	-6	no	6.715	6.877	EPSD	COSMIC	5.915	Up-regulation
CMGC_MAPK_p38_MAPK14_ST	P27816	MAP4	Q16539	MAPK14	S510	L516M	516	Missense	distal	6	no	6.715	6.891	EPSD	COSMIC	5.915	Up-regulation
CMGC_MAPK_p38_MAPK14_ST	P27816	MAP4	Q16539	MAPK14	T521	L516M	516	Missense	distal	-5	no	11.676	11.100	EPSD	COSMIC	5.915	Down-regulation
CMGC_MAPK_p38_MAPK14_ST	P27816	MAP4	Q16539	MAPK14	T521	E525K	525	Missense	distal	4	no	11.676	11.211	EPSD	COSMIC	5.915	Down-regulation
CMGC_MAPK_p38_MAPK14_ST	P27816	MAP4	Q16539	MAPK14	T571	P572L	572	Missense	proximal	1	no	9.086	1.035	EPSD	COSMIC	5.915	Loss
CMGC_MAPK_p38_MAPK14_ST	P27816	MAP4	Q16539	MAPK14	T571	T571K	571	Missense	central	0	yes	9.086	0.000	EPSD	COSMIC	5.915	Loss
CMGC_MAPK_p38_MAPK14_ST	P27816	MAP4	Q16539	MAPK14	T687	D684G	684	Missense	distal	-3	no	9.097	9.148	EPSD	COSMIC	5.915	Up-regulation
CMGC_MAPK_p38_MAPK14_ST	P27816	MAP4	Q16539	MAPK14	T687	N690Y	690	Missense	distal	3	no	9.097	9.093	EPSD	COSMIC	5.915	Down-regulation
CMGC_MAPK_p38_MAPK14_ST	P27816	MAP4	Q16539	MAPK14	S696	E698Q	698	Missense	proximal	2	no	13.579	13.042	PhosphoSitePlus;EPSD	COSMIC;GDSC;CCLE	5.915	Down-regulation
CMGC_MAPK_p38_MAPK14_ST	P27816	MAP4	Q16539	MAPK14	S696	N690Y	690	Missense	distal	-6	no	13.579	13.236	PhosphoSitePlus;EPSD	COSMIC	5.915	Down-regulation
CMGC_MAPK_p38_MAPK14_ST	P27816	MAP4	Q16539	MAPK14	S787	R785K	785	Missense	proximal	-2	no	11.725	11.122	EPSD;PhosphoSitePlus	COSMIC	5.915	Down-regulation
CMGC_MAPK_p38_MAPK14_ST	P27816	MAP4	Q16539	MAPK14	S787	R785G	785	Missense	proximal	-2	no	11.725	11.475	EPSD;PhosphoSitePlus	COSMIC	5.915	Down-regulation
CMGC_MAPK_p38_MAPK14_ST	P27816	MAP4	Q16539	MAPK14	T892	R888Q	888	Missense	distal	-4	no	8.461	8.829	EPSD	COSMIC	5.915	Up-regulation
CMGC_MAPK_p38_MAPK14_ST	P27816	MAP4	Q16539	MAPK14	T892	T892I	892	Missense	central	0	yes	8.461	0.000	EPSD	COSMIC	5.915	Loss
CMGC_MAPK_p38_MAPK14_ST	P27816	MAP4	Q16539	MAPK14	T917	R919W	919	Missense	proximal	2	no	13.292	12.794	EPSD	COSMIC	5.915	Down-regulation
CMGC_MAPK_p38_MAPK14_ST	P27816	MAP4	Q16539	MAPK14	S1145	A1140P	1140	Missense	distal	-5	no	7.107	7.443	EPSD	COSMIC;GDSC	5.915	Up-regulation
CMGC_MAPK_p38_MAPK14_ST	Q14790	CASP8	Q16539	MAPK14	S186	E184Q	184	Missense	proximal	-2	no	7.244	6.489	EPSD	COSMIC	5.915	Down-regulation
CMGC_MAPK_p38_MAPK14_ST	Q14790	CASP8	Q16539	MAPK14	S186	S186N	186	Missense	central	0	yes	7.244	0.000	EPSD	COSMIC	5.915	Loss
CMGC_MAPK_p38_MAPK14_ST	Q14790	CASP8	Q16539	MAPK14	S186	E179D	179	Missense	distal	-7	no	7.244	6.662	EPSD	COSMIC	5.915	Down-regulation
CMGC_MAPK_p38_MAPK14_ST	Q14790	CASP8	Q16539	MAPK14	S186	S188A	188	Missense	proximal	2	no	7.244	6.980	EPSD	COSMIC	5.915	Down-regulation
CMGC_MAPK_p38_MAPK14_ST	Q14790	CASP8	Q16539	MAPK14	S186	E179Q	179	Missense	distal	-7	no	7.244	6.830	EPSD	COSMIC	5.915	Down-regulation
CMGC_MAPK_p38_MAPK14_ST	Q14790	CASP8	Q16539	MAPK14	S192	S186N	186	Missense	distal	-6	no	10.734	10.311	EPSD	COSMIC	5.915	Down-regulation
CMGC_MAPK_p38_MAPK14_ST	Q14790	CASP8	Q16539	MAPK14	S192	S188A	188	Missense	distal	-4	no	10.734	10.775	EPSD	COSMIC	5.915	Up-regulation
CMGC_MAPK_p38_MAPK14_ST	Q14790	CASP8	Q16539	MAPK14	S211	S211L	211	Missense	central	0	yes	7.744	0.000	EPSD	COSMIC	5.915	Loss
CMGC_MAPK_p38_MAPK14_ST	Q14790	CASP8	Q16539	MAPK14	S211	V205I	205	Missense	distal	-6	no	7.744	7.480	EPSD	COSMIC	5.915	Down-regulation
CMGC_MAPK_p38_MAPK14_ST	Q14790	CASP8	Q16539	MAPK14	S211	S209L	209	Missense	proximal	-2	no	7.744	6.853	EPSD	COSMIC	5.915	Down-regulation
CMGC_MAPK_p38_MAPK14_ST	Q14790	CASP8	Q16539	MAPK14	S211	T207I	207	Missense	distal	-4	no	7.744	7.634	EPSD	COSMIC	5.915	Down-regulation
CMGC_MAPK_p38_MAPK14_ST	Q14790	CASP8	Q16539	MAPK14	S211	S211C	211	Missense	central	0	yes	7.744	0.000	EPSD	COSMIC	5.915	Loss
CMGC_MAPK_p38_MAPK14_ST	Q14790	CASP8	Q16539	MAPK14	S211	D216G	216	Missense	distal	5	no	7.744	8.033	EPSD	COSMIC	5.915	Up-regulation
CMGC_MAPK_p38_MAPK14_ST	Q14790	CASP8	Q16539	MAPK14	S211	P212L	212	Missense	proximal	1	no	7.744	-0.307	EPSD	COSMIC	5.915	Loss
CMGC_MAPK_p38_MAPK14_ST	Q14790	CASP8	Q16539	MAPK14	S211	P212T	212	Missense	proximal	1	no	7.744	0.291	EPSD	COSMIC	5.915	Loss
CMGC_MAPK_p38_MAPK14_ST	Q14790	CASP8	Q16539	MAPK14	S211	P212A	212	Missense	proximal	1	no	7.744	1.426	EPSD	COSMIC	5.915	Loss
CMGC_MAPK_p38_MAPK14_ST	Q14790	CASP8	Q16539	MAPK14	S211	R213S	213	Missense	proximal	2	no	7.744	7.890	EPSD	COSMIC	5.915	Up-regulation
CMGC_MAPK_p38_MAPK14_ST	Q14790	CASP8	Q16539	MAPK14	T221	L222P	222	Missense	proximal	1	no	1.970	10.020	EPSD	COSMIC	5.915	Gain
CMGC_MAPK_p38_MAPK14_ST	Q14790	CASP8	Q16539	MAPK14	T273	A267T	267	Missense	distal	-6	no	5.645	5.915	EPSD	COSMIC	5.915	Gain
CMGC_MAPK_p38_MAPK14_ST	Q14790	CASP8	Q16539	MAPK14	T273	H278N	278	Missense	distal	5	no	5.645	6.314	EPSD	COSMIC	5.915	Gain
CMGC_MAPK_p38_MAPK14_ST	Q14790	CASP8	Q16539	MAPK14	T273	H278Y	278	Missense	distal	5	no	5.645	6.371	EPSD	COSMIC	5.915	Gain
CMGC_MAPK_p38_MAPK14_ST	Q14790	CASP8	Q16539	MAPK14	S387	L385P	385	Missense	proximal	-2	no	6.638	8.018	EPSD	COSMIC	5.915	Up-regulation
CMGC_MAPK_p38_MAPK14_ST	Q14790	CASP8	Q16539	MAPK14	S387	T390I	390	Missense	distal	3	no	6.638	6.721	EPSD	COSMIC	5.915	Up-regulation
CMGC_MAPK_p38_MAPK14_ST	Q14790	CASP8	Q16539	MAPK14	S387	P394L	394	Missense	distal	7	no	6.638	6.475	EPSD	COSMIC	5.915	Down-regulation
CMGC_MAPK_p38_MAPK14_ST	Q14790	CASP8	Q16539	MAPK14	S387	D384N	384	Missense	distal	-3	no	6.638	6.480	EPSD	COSMIC	5.915	Down-regulation
CMGC_MAPK_p38_MAPK14_ST	Q14790	CASP8	Q16539	MAPK14	S387	P388S	388	Missense	proximal	1	no	6.638	-0.646	EPSD	COSMIC;CCLE	5.915	Loss
CMGC_MAPK_p38_MAPK14_ST	Q14790	CASP8	Q16539	MAPK14	S387	P394S	394	Missense	distal	7	no	6.638	6.860	EPSD	COSMIC	5.915	Up-regulation
CMGC_MAPK_p38_MAPK14_ST	Q14790	CASP8	Q16539	MAPK14	S387	R391G	391	Missense	distal	4	no	6.638	7.123	EPSD	COSMIC	5.915	Up-regulation
CMGC_MAPK_p38_MAPK14_ST	Q14790	CASP8	Q16539	MAPK14	S387	P394Q	394	Missense	distal	7	no	6.638	6.701	EPSD	COSMIC	5.915	Up-regulation
CMGC_MAPK_p38_MAPK14_ST	Q14790	CASP8	Q16539	MAPK14	S387	T390M	390	Missense	distal	3	no	6.638	6.662	EPSD	COSMIC	5.915	Up-regulation
CMGC_MAPK_p38_MAPK14_ST	Q14790	CASP8	Q16539	MAPK14	S387	P388L	388	Missense	proximal	1	no	6.638	-1.413	EPSD	COSMIC	5.915	Loss
CMGC_MAPK_p38_MAPK14_ST	Q14790	CASP8	Q16539	MAPK14	S387	S386L	386	Missense	proximal	-1	no	6.638	6.916	EPSD	COSMIC	5.915	Up-regulation
CMGC_MAPK_p38_MAPK14_ST	Q14790	CASP8	Q16539	MAPK14	S387	P394T	394	Missense	distal	7	no	6.638	6.539	EPSD	COSMIC	5.915	Down-regulation
CMGC_MAPK_p38_MAPK14_ST	Q9H211	CDT1	Q16539	MAPK14	S42	T44P	44	Missense	proximal	2	no	6.554	6.412	EPSD	COSMIC	5.915	Down-regulation
CMGC_MAPK_p38_MAPK14_ST	Q9H211	CDT1	Q16539	MAPK14	S79	T82I	82	Missense	distal	3	no	13.678	13.761	EPSD	COSMIC	5.915	Up-regulation
CMGC_MAPK_p38_MAPK14_ST	Q9H211	CDT1	Q16539	MAPK14	T82	P89T	89	Missense	distal	7	no	9.524	9.424	EPSD	COSMIC	5.915	Down-regulation
CMGC_MAPK_p38_MAPK14_ST	Q9H211	CDT1	Q16539	MAPK14	T82	T82I	82	Missense	central	0	yes	9.524	0.000	EPSD	COSMIC	5.915	Loss
CMGC_MAPK_p38_MAPK14_ST	Q9H211	CDT1	Q16539	MAPK14	S93	P89T	89	Missense	distal	-4	no	10.051	10.241	EPSD	COSMIC	5.915	Up-regulation
CMGC_MAPK_p38_MAPK14_ST	Q9H211	CDT1	Q16539	MAPK14	S386	A388V	388	Missense	proximal	2	no	6.324	6.160	EPSD	COSMIC	5.915	Down-regulation
CMGC_MAPK_p38_MAPK14_ST	Q9H211	CDT1	Q16539	MAPK14	S386	L382F	382	Missense	distal	-4	no	6.324	6.429	EPSD	COSMIC;GDSC	5.915	Up-regulation
CMGC_MAPK_p38_MAPK14_ST	Q9H211	CDT1	Q16539	MAPK14	S386	A388G	388	Missense	proximal	2	no	6.324	6.359	EPSD	COSMIC	5.915	Up-regulation
CMGC_MAPK_p38_MAPK14_ST	Q9H211	CDT1	Q16539	MAPK14	S391	A388V	388	Missense	distal	-3	no	11.410	9.909	PhosphoSitePlus;EPSD	COSMIC	5.915	Down-regulation
CMGC_MAPK_p38_MAPK14_ST	Q9H211	CDT1	Q16539	MAPK14	S391	A388G	388	Missense	distal	-3	no	11.410	10.884	PhosphoSitePlus;EPSD	COSMIC	5.915	Down-regulation
CMGC_MAPK_p38_MAPK14_ST	Q9H211	CDT1	Q16539	MAPK14	S394	A388V	388	Missense	distal	-6	no	11.973	11.485	EPSD	COSMIC	5.915	Down-regulation
CMGC_MAPK_p38_MAPK14_ST	Q9H211	CDT1	Q16539	MAPK14	S394	P400S	400	Missense	distal	6	no	11.973	11.961	EPSD	COSMIC	5.915	Down-regulation
CMGC_MAPK_p38_MAPK14_ST	Q9H211	CDT1	Q16539	MAPK14	S394	A388G	388	Missense	distal	-6	no	11.973	12.035	EPSD	COSMIC	5.915	Up-regulation
CMGC_MAPK_p38_MAPK14_ST	Q9H211	CDT1	Q16539	MAPK14	T402	P408H	408	Missense	distal	6	no	11.215	11.096	EPSD;PhosphoSitePlus	COSMIC	5.915	Down-regulation
CMGC_MAPK_p38_MAPK14_ST	Q9H211	CDT1	Q16539	MAPK14	T402	P400S	400	Missense	proximal	-2	no	11.215	10.727	EPSD;PhosphoSitePlus	COSMIC	5.915	Down-regulation
CMGC_MAPK_p38_MAPK14_ST	Q9H211	CDT1	Q16539	MAPK14	T402	P403T	403	Missense	proximal	1	no	11.215	3.762	EPSD;PhosphoSitePlus	COSMIC	5.915	Loss
CMGC_MAPK_p38_MAPK14_ST	Q9H211	CDT1	Q16539	MAPK14	T402	P407S	407	Missense	distal	5	no	11.215	11.666	EPSD;PhosphoSitePlus	COSMIC	5.915	Up-regulation
CMGC_MAPK_p38_MAPK14_ST	Q9H211	CDT1	Q16539	MAPK14	T402	T402I	402	Missense	central	0	yes	11.215	0.000	EPSD;PhosphoSitePlus	COSMIC	5.915	Loss
CMGC_MAPK_p38_MAPK14_ST	Q9H211	CDT1	Q16539	MAPK14	T406	P408H	408	Missense	proximal	2	no	11.078	10.926	EPSD;PhosphoSitePlus	COSMIC	5.915	Down-regulation
CMGC_MAPK_p38_MAPK14_ST	Q9H211	CDT1	Q16539	MAPK14	T406	P400S	400	Missense	distal	-6	no	11.078	11.685	EPSD;PhosphoSitePlus	COSMIC	5.915	Up-regulation
CMGC_MAPK_p38_MAPK14_ST	Q9H211	CDT1	Q16539	MAPK14	T406	P403T	403	Missense	distal	-3	no	11.078	11.524	EPSD;PhosphoSitePlus	COSMIC	5.915	Up-regulation
CMGC_MAPK_p38_MAPK14_ST	Q9H211	CDT1	Q16539	MAPK14	T406	P407S	407	Missense	proximal	1	no	11.078	3.794	EPSD;PhosphoSitePlus	COSMIC	5.915	Loss
CMGC_MAPK_p38_MAPK14_ST	Q9H211	CDT1	Q16539	MAPK14	T406	T402I	402	Missense	distal	-4	no	11.078	10.968	EPSD;PhosphoSitePlus	COSMIC	5.915	Down-regulation
CMGC_MAPK_p38_MAPK14_ST	Q9H211	CDT1	Q16539	MAPK14	S411	P408H	408	Missense	distal	-3	no	10.413	9.936	EPSD;PhosphoSitePlus	COSMIC	5.915	Down-regulation
CMGC_MAPK_p38_MAPK14_ST	Q9H211	CDT1	Q16539	MAPK14	S411	P407S	407	Missense	distal	-4	no	10.413	10.326	EPSD;PhosphoSitePlus	COSMIC	5.915	Down-regulation
CMGC_MAPK_p38_MAPK14_ST	Q9H211	CDT1	Q16539	MAPK14	S413	P407S	407	Missense	distal	-6	no	5.578	6.185	EPSD	COSMIC	5.915	Gain
CMGC_MAPK_p38_MAPK14_ST	Q9H211	CDT1	Q16539	MAPK14	S491	H498Y	498	Missense	distal	7	no	12.197	12.739	EPSD;PhosphoSitePlus	COSMIC	5.915	Up-regulation
CMGC_MAPK_p38_MAPK14_ST	Q9H211	CDT1	Q16539	MAPK14	S491	S485N	485	Missense	distal	-6	no	12.197	11.774	EPSD;PhosphoSitePlus	COSMIC	5.915	Down-regulation
CMGC_MAPK_p38_MAPK14_ST	Q00613	HSF1	Q16539	MAPK14	S244	S237L	237	Missense	distal	-7	no	16.698	16.418	EPSD	COSMIC	5.915	Down-regulation
CMGC_MAPK_p38_MAPK14_ST	Q00613	HSF1	Q16539	MAPK14	S244	P239H	239	Missense	distal	-5	no	16.698	17.012	EPSD	COSMIC	5.915	Up-regulation
CMGC_MAPK_p38_MAPK14_ST	Q00613	HSF1	Q16539	MAPK14	S244	S244F	244	Missense	central	0	yes	16.698	0.000	EPSD	COSMIC	5.915	Loss
CMGC_MAPK_p38_MAPK14_ST	Q00613	HSF1	Q16539	MAPK14	S275	S279F	279	Missense	distal	4	no	14.111	12.537	EPSD	COSMIC	5.915	Down-regulation
CMGC_MAPK_p38_MAPK14_ST	Q00613	HSF1	Q16539	MAPK14	S275	P280L	280	Missense	distal	5	no	14.111	13.614	EPSD	COSMIC	5.915	Down-regulation
CMGC_MAPK_p38_MAPK14_ST	Q00613	HSF1	Q16539	MAPK14	S275	I268V	268	Missense	distal	-7	no	14.111	13.827	EPSD	COSMIC	5.915	Down-regulation
CMGC_MAPK_p38_MAPK14_ST	Q00613	HSF1	Q16539	MAPK14	S275	G281S	281	Missense	distal	6	no	14.111	13.990	EPSD	COSMIC	5.915	Down-regulation
CMGC_MAPK_p38_MAPK14_ST	Q00613	HSF1	Q16539	MAPK14	S279	S279F	279	Missense	central	0	yes	10.463	0.000	EPSD	COSMIC	5.915	Loss
CMGC_MAPK_p38_MAPK14_ST	Q00613	HSF1	Q16539	MAPK14	S279	P280L	280	Missense	proximal	1	no	10.463	2.412	EPSD	COSMIC	5.915	Loss
CMGC_MAPK_p38_MAPK14_ST	Q00613	HSF1	Q16539	MAPK14	S279	G281S	281	Missense	proximal	2	no	10.463	10.692	EPSD	COSMIC	5.915	Up-regulation
CMGC_MAPK_p38_MAPK14_ST	Q00613	HSF1	Q16539	MAPK14	S279	S283N	283	Missense	distal	4	no	10.463	9.946	EPSD	COSMIC	5.915	Down-regulation
CMGC_MAPK_p38_MAPK14_ST	Q00613	HSF1	Q16539	MAPK14	S292	R287K	287	Missense	distal	-5	no	11.025	10.889	EPSD	COSMIC	5.915	Down-regulation
CMGC_MAPK_p38_MAPK14_ST	Q00613	HSF1	Q16539	MAPK14	S303	S303G	303	Missense	central	0	yes	12.833	0.000	EPSD;PhosphoSitePlus	COSMIC	5.915	Loss
CMGC_MAPK_p38_MAPK14_ST	Q00613	HSF1	Q16539	MAPK14	S303	P304L	304	Missense	proximal	1	no	12.833	4.782	EPSD;PhosphoSitePlus	COSMIC;GDSC	5.915	Loss
CMGC_MAPK_p38_MAPK14_ST	Q00613	HSF1	Q16539	MAPK14	S303	R309G	309	Missense	distal	6	no	12.833	12.954	EPSD;PhosphoSitePlus	COSMIC	5.915	Up-regulation
CMGC_MAPK_p38_MAPK14_ST	Q00613	HSF1	Q16539	MAPK14	S307	S303G	303	Missense	distal	-4	no	11.613	11.611	PhosphoSitePlus;EPSD	COSMIC	5.915	Down-regulation
CMGC_MAPK_p38_MAPK14_ST	Q00613	HSF1	Q16539	MAPK14	S307	P304L	304	Missense	distal	-3	no	11.613	10.646	PhosphoSitePlus;EPSD	COSMIC;GDSC	5.915	Down-regulation
CMGC_MAPK_p38_MAPK14_ST	Q00613	HSF1	Q16539	MAPK14	S307	R309G	309	Missense	proximal	2	no	11.613	11.530	PhosphoSitePlus;EPSD	COSMIC	5.915	Down-regulation
CMGC_MAPK_p38_MAPK14_ST	Q00613	HSF1	Q16539	MAPK14	S314	R309G	309	Missense	distal	-5	no	11.567	11.730	EPSD	COSMIC	5.915	Up-regulation
CMGC_MAPK_p38_MAPK14_ST	Q00613	HSF1	Q16539	MAPK14	S314	P318T	318	Missense	distal	4	no	11.567	11.746	EPSD	COSMIC	5.915	Up-regulation
CMGC_MAPK_p38_MAPK14_ST	Q00613	HSF1	Q16539	MAPK14	S326	L330V	330	Missense	distal	4	no	11.459	11.798	EPSD;PhosphoSitePlus	COSMIC	5.915	Up-regulation
CMGC_MAPK_p38_MAPK14_ST	Q00613	HSF1	Q16539	MAPK14	S326	P327Q	327	Missense	proximal	1	no	11.459	4.250	EPSD;PhosphoSitePlus	COSMIC	5.915	Loss
CMGC_MAPK_p38_MAPK14_ST	Q00613	HSF1	Q16539	MAPK14	S363	S363P	363	Missense	central	0	yes	14.180	0.000	EPSD	COSMIC	5.915	Loss
CMGC_MAPK_p38_MAPK14_ST	Q00613	HSF1	Q16539	MAPK14	S363	P365Q	365	Missense	proximal	2	no	14.180	13.985	EPSD	COSMIC	5.915	Down-regulation
CMGC_MAPK_p38_MAPK14_ST	Q00613	HSF1	Q16539	MAPK14	S363	D356N	356	Missense	distal	-7	no	14.180	14.399	EPSD	COSMIC	5.915	Up-regulation
CMGC_MAPK_p38_MAPK14_ST	Q00613	HSF1	Q16539	MAPK14	S363	P365T	365	Missense	proximal	2	no	14.180	14.321	EPSD	COSMIC	5.915	Up-regulation
CMGC_MAPK_p38_MAPK14_ST	Q00613	HSF1	Q16539	MAPK14	S363	E358K	358	Missense	distal	-5	no	14.180	14.514	EPSD	COSMIC	5.915	Up-regulation
CMGC_MAPK_p38_MAPK14_ST	Q00613	HSF1	Q16539	MAPK14	S363	P365L	365	Missense	proximal	2	no	14.180	14.067	EPSD	COSMIC	5.915	Down-regulation
CMGC_MAPK_p38_MAPK14_ST	Q00613	HSF1	Q16539	MAPK14	T369	S363P	363	Missense	distal	-6	no	12.214	11.607	EPSD	COSMIC	5.915	Down-regulation
CMGC_MAPK_p38_MAPK14_ST	Q00613	HSF1	Q16539	MAPK14	T369	P365Q	365	Missense	distal	-4	no	12.214	12.505	EPSD	COSMIC	5.915	Up-regulation
CMGC_MAPK_p38_MAPK14_ST	Q00613	HSF1	Q16539	MAPK14	T369	P365T	365	Missense	distal	-4	no	12.214	12.403	EPSD	COSMIC	5.915	Up-regulation
CMGC_MAPK_p38_MAPK14_ST	Q00613	HSF1	Q16539	MAPK14	T369	L374F	374	Missense	distal	5	no	12.214	11.720	EPSD	COSMIC	5.915	Down-regulation
CMGC_MAPK_p38_MAPK14_ST	Q00613	HSF1	Q16539	MAPK14	T369	P365L	365	Missense	distal	-4	no	12.214	12.726	EPSD	COSMIC	5.915	Up-regulation
CMGC_MAPK_p38_MAPK14_ST	Q00613	HSF1	Q16539	MAPK14	S419	L417Q	417	Missense	proximal	-2	no	11.046	11.411	EPSD	COSMIC	5.915	Up-regulation
CMGC_MAPK_p38_MAPK14_ST	Q00613	HSF1	Q16539	MAPK14	S419	V422M	422	Missense	distal	3	no	11.046	11.041	EPSD	COSMIC	5.915	Down-regulation
CMGC_MAPK_p38_MAPK14_ST	Q00613	HSF1	Q16539	MAPK14	S419	S419N	419	Missense	central	0	yes	11.046	0.000	EPSD	COSMIC	5.915	Loss
CMGC_MAPK_p38_MAPK14_ST	Q00613	HSF1	Q16539	MAPK14	S444	E447K	447	Missense	distal	3	no	11.173	11.221	EPSD	COSMIC	5.915	Up-regulation
CMGC_MAPK_p38_MAPK14_ST	Q00613	HSF1	Q16539	MAPK14	S458	P452H	452	Missense	distal	-6	no	10.291	9.829	EPSD	COSMIC	5.915	Down-regulation
CMGC_MAPK_p38_MAPK14_ST	P17844	DDX5	Q16539	MAPK14	T75	I82V	82	Missense	distal	7	no	5.403	6.049	EPSD	COSMIC	5.915	Gain
CMGC_MAPK_p38_MAPK14_ST	P17844	DDX5	Q16539	MAPK14	T446	P447L	447	Missense	proximal	1	no	9.682	1.631	PhosphoSitePlus;EPSD	COSMIC	5.915	Loss
CMGC_MAPK_p38_MAPK14_ST	P17844	DDX5	Q16539	MAPK14	T446	A441S	441	Missense	distal	-5	no	9.682	9.570	PhosphoSitePlus;EPSD	COSMIC	5.915	Down-regulation
CMGC_MAPK_p38_MAPK14_ST	P17844	DDX5	Q16539	MAPK14	T446	Q452H	452	Missense	distal	6	no	9.682	9.563	PhosphoSitePlus;EPSD	COSMIC	5.915	Down-regulation
CMGC_MAPK_p38_MAPK14_ST	P17844	DDX5	Q16539	MAPK14	T446	Q452E	452	Missense	distal	6	no	9.682	9.751	PhosphoSitePlus;EPSD	COSMIC	5.915	Up-regulation
CMGC_MAPK_p38_MAPK14_ST	P17844	DDX5	Q16539	MAPK14	S519	D525Y	525	Missense	distal	6	no	6.564	6.602	EPSD	COSMIC	5.915	Up-regulation
CMGC_MAPK_p38_MAPK14_ST	P17844	DDX5	Q16539	MAPK14	S519	Y514H	514	Missense	distal	-5	no	6.564	6.877	EPSD	COSMIC	5.915	Up-regulation
CMGC_MAPK_p38_MAPK14_ST	Q9UK80	USP21	Q16539	MAPK14	S93	P91S	91	Missense	proximal	-2	no	11.055	10.566	EPSD	COSMIC	5.915	Down-regulation
CMGC_MAPK_p38_MAPK14_ST	Q9UK80	USP21	Q16539	MAPK14	S93	P91A	91	Missense	proximal	-2	no	11.055	10.392	EPSD	COSMIC;GDSC	5.915	Down-regulation
CMGC_MAPK_p38_MAPK14_ST	Q9UK80	USP21	Q16539	MAPK14	T174	A178V	178	Missense	distal	4	no	6.744	6.310	EPSD	COSMIC	5.915	Down-regulation
CMGC_MAPK_p38_MAPK14_ST	Q9UK80	USP21	Q16539	MAPK14	T174	G181D	181	Missense	distal	7	no	6.744	6.910	EPSD	COSMIC	5.915	Up-regulation
CMGC_MAPK_p38_MAPK14_ST	Q9UK80	USP21	Q16539	MAPK14	S182	S182F	182	Missense	central	0	yes	6.766	0.000	EPSD	COSMIC	5.915	Loss
CMGC_MAPK_p38_MAPK14_ST	Q9UK80	USP21	Q16539	MAPK14	S182	A178V	178	Missense	distal	-4	no	6.766	7.048	EPSD	COSMIC	5.915	Up-regulation
CMGC_MAPK_p38_MAPK14_ST	Q9UK80	USP21	Q16539	MAPK14	S182	G181D	181	Missense	proximal	-1	no	6.766	6.810	EPSD	COSMIC	5.915	Up-regulation
CMGC_MAPK_p38_MAPK14_ST	Q9UK80	USP21	Q16539	MAPK14	S182	A188V	188	Missense	distal	6	no	6.766	6.470	EPSD	COSMIC	5.915	Down-regulation
CMGC_MAPK_p38_MAPK14_ST	Q9UK80	USP21	Q16539	MAPK14	S335	R338H	338	Missense	distal	3	no	10.321	10.392	EPSD	COSMIC	5.915	Up-regulation
CMGC_MAPK_p38_MAPK14_ST	Q9UK80	USP21	Q16539	MAPK14	S499	G498D	498	Missense	proximal	-1	no	9.842	9.886	EPSD	COSMIC	5.915	Up-regulation
CMGC_MAPK_p38_MAPK14_ST	P04637	TP53	Q16539	MAPK14	S15	E11Q	11	Missense	distal	-4	no	5.700	6.378	EPSD;PhosphoSitePlus	COSMIC;GDSC;CCLE	5.915	Gain
CMGC_MAPK_p38_MAPK14_ST	P04637	TP53	Q16539	MAPK14	S15	F19S	19	Missense	distal	4	no	5.700	7.274	EPSD;PhosphoSitePlus	COSMIC	5.915	Gain
CMGC_MAPK_p38_MAPK14_ST	P04637	TP53	Q16539	MAPK14	S33	M40I	40	Missense	distal	7	no	11.723	11.121	EPSD;PhosphoSitePlus	COSMIC	5.915	Down-regulation
CMGC_MAPK_p38_MAPK14_ST	P04637	TP53	Q16539	MAPK14	S33	V31I	31	Missense	proximal	-2	no	11.723	11.982	EPSD;PhosphoSitePlus	COSMIC;GDSC;CCLE	5.915	Up-regulation
CMGC_MAPK_p38_MAPK14_ST	P04637	TP53	Q16539	MAPK14	S33	P36L	36	Missense	distal	3	no	11.723	11.757	EPSD;PhosphoSitePlus	COSMIC;GDSC;CCLE	5.915	Up-regulation
CMGC_MAPK_p38_MAPK14_ST	P04637	TP53	Q16539	MAPK14	S33	L35F	35	Missense	proximal	2	no	11.723	11.546	EPSD;PhosphoSitePlus	COSMIC	5.915	Down-regulation
CMGC_MAPK_p38_MAPK14_ST	P04637	TP53	Q16539	MAPK14	S33	Q38L	38	Missense	distal	5	no	11.723	11.435	EPSD;PhosphoSitePlus	COSMIC	5.915	Down-regulation
CMGC_MAPK_p38_MAPK14_ST	P04637	TP53	Q16539	MAPK14	S33	S37T	37	Missense	distal	4	no	11.723	11.462	EPSD;PhosphoSitePlus	COSMIC	5.915	Down-regulation
CMGC_MAPK_p38_MAPK14_ST	P04637	TP53	Q16539	MAPK14	S33	L26P	26	Missense	distal	-7	no	11.723	11.916	EPSD;PhosphoSitePlus	COSMIC	5.915	Up-regulation
CMGC_MAPK_p38_MAPK14_ST	P04637	TP53	Q16539	MAPK14	S33	P36S	36	Missense	distal	3	no	11.723	11.683	EPSD;PhosphoSitePlus	COSMIC;GDSC;CCLE	5.915	Down-regulation
CMGC_MAPK_p38_MAPK14_ST	P04637	TP53	Q16539	MAPK14	S33	A39V	39	Missense	distal	6	no	11.723	11.428	EPSD;PhosphoSitePlus	COSMIC	5.915	Down-regulation
CMGC_MAPK_p38_MAPK14_ST	P04637	TP53	Q16539	MAPK14	S33	A39S	39	Missense	distal	6	no	11.723	11.668	EPSD;PhosphoSitePlus	COSMIC	5.915	Down-regulation
CMGC_MAPK_p38_MAPK14_ST	P04637	TP53	Q16539	MAPK14	S33	N30K	30	Missense	distal	-3	no	11.723	11.695	EPSD;PhosphoSitePlus	COSMIC	5.915	Down-regulation
CMGC_MAPK_p38_MAPK14_ST	P04637	TP53	Q16539	MAPK14	S33	A39T	39	Missense	distal	6	no	11.723	11.706	EPSD;PhosphoSitePlus	COSMIC	5.915	Down-regulation
CMGC_MAPK_p38_MAPK14_ST	P04637	TP53	Q16539	MAPK14	S33	P27T	27	Missense	distal	-6	no	11.723	12.057	EPSD;PhosphoSitePlus	COSMIC	5.915	Up-regulation
CMGC_MAPK_p38_MAPK14_ST	P04637	TP53	Q16539	MAPK14	S33	P36R	36	Missense	distal	3	no	11.723	11.711	EPSD;PhosphoSitePlus	COSMIC	5.915	Down-regulation
CMGC_MAPK_p38_MAPK14_ST	P04637	TP53	Q16539	MAPK14	S33	L35R	35	Missense	proximal	2	no	11.723	12.067	EPSD;PhosphoSitePlus	COSMIC	5.915	Up-regulation
CMGC_MAPK_p38_MAPK14_ST	P04637	TP53	Q16539	MAPK14	S33	L35H	35	Missense	proximal	2	no	11.723	11.684	EPSD;PhosphoSitePlus	COSMIC	5.915	Down-regulation
CMGC_MAPK_p38_MAPK14_ST	P04637	TP53	Q16539	MAPK14	S33	L35P	35	Missense	proximal	2	no	11.723	11.836	EPSD;PhosphoSitePlus	COSMIC	5.915	Up-regulation
CMGC_MAPK_p38_MAPK14_ST	P04637	TP53	Q16539	MAPK14	S33	L35I	35	Missense	proximal	2	no	11.723	11.733	EPSD;PhosphoSitePlus	COSMIC	5.915	Up-regulation
CMGC_MAPK_p38_MAPK14_ST	P04637	TP53	Q16539	MAPK14	S33	L35V	35	Missense	proximal	2	no	11.723	11.785	EPSD;PhosphoSitePlus	COSMIC	5.915	Up-regulation
CMGC_MAPK_p38_MAPK14_ST	P04637	TP53	Q16539	MAPK14	S46	M40I	40	Missense	distal	-6	no	11.214	10.779	PhosphoSitePlus;EPSD	COSMIC	5.915	Down-regulation
CMGC_MAPK_p38_MAPK14_ST	P04637	TP53	Q16539	MAPK14	S46	W53C	53	Missense	distal	7	no	11.214	11.303	PhosphoSitePlus;EPSD	COSMIC	5.915	Up-regulation
CMGC_MAPK_p38_MAPK14_ST	P04637	TP53	Q16539	MAPK14	S46	W53G	53	Missense	distal	7	no	11.214	11.725	PhosphoSitePlus;EPSD	COSMIC	5.915	Up-regulation
CMGC_MAPK_p38_MAPK14_ST	P04637	TP53	Q16539	MAPK14	S46	S46F	46	Missense	central	0	yes	11.214	0.000	PhosphoSitePlus;EPSD	COSMIC	5.915	Loss
CMGC_MAPK_p38_MAPK14_ST	P04637	TP53	Q16539	MAPK14	S46	D49Y	49	Missense	distal	3	no	11.214	11.204	PhosphoSitePlus;EPSD	COSMIC	5.915	Down-regulation
CMGC_MAPK_p38_MAPK14_ST	P04637	TP53	Q16539	MAPK14	S46	P47L	47	Missense	proximal	1	no	11.214	3.163	PhosphoSitePlus;EPSD	COSMIC	5.915	Loss
CMGC_MAPK_p38_MAPK14_ST	P04637	TP53	Q16539	MAPK14	S46	D49H	49	Missense	distal	3	no	11.214	11.262	PhosphoSitePlus;EPSD	COSMIC;GDSC;CCLE	5.915	Up-regulation
CMGC_MAPK_p38_MAPK14_ST	P04637	TP53	Q16539	MAPK14	S46	P47S	47	Missense	proximal	1	no	11.214	3.930	PhosphoSitePlus;EPSD	COSMIC	5.915	Loss
CMGC_MAPK_p38_MAPK14_ST	P04637	TP53	Q16539	MAPK14	S46	D41N	41	Missense	distal	-5	no	11.214	11.055	PhosphoSitePlus;EPSD	COSMIC	5.915	Down-regulation
CMGC_MAPK_p38_MAPK14_ST	P04637	TP53	Q16539	MAPK14	S46	D48H	48	Missense	proximal	2	no	11.214	11.172	PhosphoSitePlus;EPSD	COSMIC	5.915	Down-regulation
CMGC_MAPK_p38_MAPK14_ST	P04637	TP53	Q16539	MAPK14	S46	D49N	49	Missense	distal	3	no	11.214	11.208	PhosphoSitePlus;EPSD	COSMIC	5.915	Down-regulation
CMGC_MAPK_p38_MAPK14_ST	P04637	TP53	Q16539	MAPK14	S46	M44I	44	Missense	proximal	-2	no	11.214	11.208	PhosphoSitePlus;EPSD	COSMIC	5.915	Down-regulation
CMGC_MAPK_p38_MAPK14_ST	P04637	TP53	Q16539	MAPK14	S46	Q52H	52	Missense	distal	6	no	11.214	11.095	PhosphoSitePlus;EPSD	COSMIC	5.915	Down-regulation
CMGC_MAPK_p38_MAPK14_ST	P04637	TP53	Q16539	MAPK14	S46	D49V	49	Missense	distal	3	no	11.214	11.205	PhosphoSitePlus;EPSD	COSMIC	5.915	Down-regulation
CMGC_MAPK_p38_MAPK14_ST	P04637	TP53	Q16539	MAPK14	S46	A39V	39	Missense	distal	-7	no	11.214	10.396	PhosphoSitePlus;EPSD	COSMIC	5.915	Down-regulation
CMGC_MAPK_p38_MAPK14_ST	P04637	TP53	Q16539	MAPK14	S46	A39S	39	Missense	distal	-7	no	11.214	11.101	PhosphoSitePlus;EPSD	COSMIC	5.915	Down-regulation
CMGC_MAPK_p38_MAPK14_ST	P04637	TP53	Q16539	MAPK14	S46	D42Y	42	Missense	distal	-4	no	11.214	10.717	PhosphoSitePlus;EPSD	COSMIC	5.915	Down-regulation
CMGC_MAPK_p38_MAPK14_ST	P04637	TP53	Q16539	MAPK14	S46	M44R	44	Missense	proximal	-2	no	11.214	11.337	PhosphoSitePlus;EPSD	COSMIC	5.915	Up-regulation
CMGC_MAPK_p38_MAPK14_ST	P04637	TP53	Q16539	MAPK14	S46	S46P	46	Missense	central	0	yes	11.214	0.000	PhosphoSitePlus;EPSD	COSMIC	5.915	Loss
CMGC_MAPK_p38_MAPK14_ST	P04637	TP53	Q16539	MAPK14	S46	M44V	44	Missense	proximal	-2	no	11.214	10.949	PhosphoSitePlus;EPSD	COSMIC	5.915	Down-regulation
CMGC_MAPK_p38_MAPK14_ST	P04637	TP53	Q16539	MAPK14	S46	L45P	45	Missense	proximal	-1	no	11.214	11.029	PhosphoSitePlus;EPSD	COSMIC	5.915	Down-regulation
CMGC_MAPK_p38_MAPK14_ST	P04637	TP53	Q16539	MAPK14	S46	M44T	44	Missense	proximal	-2	no	11.214	11.306	PhosphoSitePlus;EPSD	COSMIC	5.915	Up-regulation
CMGC_MAPK_p38_MAPK14_ST	P04637	TP53	Q16539	MAPK14	S46	A39T	39	Missense	distal	-7	no	11.214	11.031	PhosphoSitePlus;EPSD	COSMIC	5.915	Down-regulation
CMGC_MAPK_p38_MAPK14_ST	P04637	TP53	Q16539	MAPK14	S46	L43F	43	Missense	distal	-3	no	11.214	10.238	PhosphoSitePlus;EPSD	COSMIC	5.915	Down-regulation
CMGC_MAPK_p38_MAPK14_ST	P04637	TP53	Q16539	MAPK14	S46	D41H	41	Missense	distal	-5	no	11.214	11.352	PhosphoSitePlus;EPSD	COSMIC	5.915	Up-regulation
CMGC_MAPK_p38_MAPK14_ST	P04637	TP53	Q16539	MAPK14	S46	D49E	49	Missense	distal	3	no	11.214	11.159	PhosphoSitePlus;EPSD	COSMIC	5.915	Down-regulation
CMGC_MAPK_p38_MAPK14_ST	P04637	TP53	Q16539	MAPK14	S46	D49G	49	Missense	distal	3	no	11.214	11.205	PhosphoSitePlus;EPSD	COSMIC	5.915	Down-regulation
CMGC_MAPK_p38_MAPK14_ST	P04637	TP53	Q16539	MAPK14	S46	D48A	48	Missense	proximal	2	no	11.214	11.436	PhosphoSitePlus;EPSD	COSMIC	5.915	Up-regulation
CMGC_MAPK_p38_MAPK14_ST	P04637	TP53	Q16539	MAPK14	S46	D48Y	48	Missense	proximal	2	no	11.214	11.375	PhosphoSitePlus;EPSD	COSMIC	5.915	Up-regulation
CMGC_MAPK_p38_MAPK14_ST	P04637	TP53	Q16539	MAPK14	S46	D48E	48	Missense	proximal	2	no	11.214	11.665	PhosphoSitePlus;EPSD	COSMIC	5.915	Up-regulation
CMGC_MAPK_p38_MAPK14_ST	P04637	TP53	Q16539	MAPK14	S46	D49I	49	Missense	distal	3	no	11.214	11.259	PhosphoSitePlus;EPSD	COSMIC	5.915	Up-regulation
CMGC_MAPK_p38_MAPK14_ST	P04637	TP53	Q16539	MAPK14	S46	D41E	41	Missense	distal	-5	no	11.214	10.340	PhosphoSitePlus;EPSD	COSMIC	5.915	Down-regulation
CMGC_MAPK_p38_MAPK14_ST	P04637	TP53	Q16539	MAPK14	T81	P77A	77	Missense	distal	-4	no	7.344	7.296	EPSD	COSMIC	5.915	Down-regulation
CMGC_MAPK_p38_MAPK14_ST	P04637	TP53	Q16539	MAPK14	T81	A76T	76	Missense	distal	-5	no	7.344	7.673	EPSD	COSMIC	5.915	Up-regulation
CMGC_MAPK_p38_MAPK14_ST	P04637	TP53	Q16539	MAPK14	T81	A83T	83	Missense	proximal	2	no	7.344	7.372	EPSD	COSMIC	5.915	Up-regulation
CMGC_MAPK_p38_MAPK14_ST	P04637	TP53	Q16539	MAPK14	T81	T81I	81	Missense	central	0	yes	7.344	0.000	EPSD	COSMIC	5.915	Loss
CMGC_MAPK_p38_MAPK14_ST	P04637	TP53	Q16539	MAPK14	T81	A84V	84	Missense	distal	3	no	7.344	7.372	EPSD	COSMIC	5.915	Up-regulation
CMGC_MAPK_p38_MAPK14_ST	P04637	TP53	Q16539	MAPK14	T81	P80L	80	Missense	proximal	-1	no	7.344	7.529	EPSD	COSMIC	5.915	Up-regulation
CMGC_MAPK_p38_MAPK14_ST	P04637	TP53	Q16539	MAPK14	T81	A86V	86	Missense	distal	5	no	7.344	7.325	EPSD	COSMIC	5.915	Down-regulation
CMGC_MAPK_p38_MAPK14_ST	P04637	TP53	Q16539	MAPK14	T81	P85S	85	Missense	distal	4	no	7.344	7.783	EPSD	COSMIC	5.915	Up-regulation
CMGC_MAPK_p38_MAPK14_ST	P04637	TP53	Q16539	MAPK14	T81	A79T	79	Missense	proximal	-2	no	7.344	7.287	EPSD	COSMIC	5.915	Down-regulation
CMGC_MAPK_p38_MAPK14_ST	P04637	TP53	Q16539	MAPK14	T81	A84G	84	Missense	distal	3	no	7.344	7.371	EPSD	COSMIC	5.915	Up-regulation
CMGC_MAPK_p38_MAPK14_ST	P04637	TP53	Q16539	MAPK14	T81	A78V	78	Missense	distal	-3	no	7.344	5.843	EPSD	COSMIC	5.915	Loss
CMGC_MAPK_p38_MAPK14_ST	P04637	TP53	Q16539	MAPK14	T81	A78S	78	Missense	distal	-3	no	7.344	7.756	EPSD	COSMIC	5.915	Up-regulation
CMGC_MAPK_p38_MAPK14_ST	P04637	TP53	Q16539	MAPK14	T81	P87L	87	Missense	distal	6	no	7.344	7.205	EPSD	COSMIC	5.915	Down-regulation
CMGC_MAPK_p38_MAPK14_ST	P04637	TP53	Q16539	MAPK14	T81	P85L	85	Missense	distal	4	no	7.344	6.705	EPSD	COSMIC	5.915	Down-regulation
CMGC_MAPK_p38_MAPK14_ST	P04637	TP53	Q16539	MAPK14	T81	P82S	82	Missense	proximal	1	no	7.344	0.060	EPSD	COSMIC	5.915	Loss
CMGC_MAPK_p38_MAPK14_ST	P04637	TP53	Q16539	MAPK14	T81	P77S	77	Missense	distal	-4	no	7.344	7.256	EPSD	COSMIC	5.915	Down-regulation
CMGC_MAPK_p38_MAPK14_ST	P04637	TP53	Q16539	MAPK14	T81	P80S	80	Missense	proximal	-1	no	7.344	7.251	EPSD	COSMIC	5.915	Down-regulation
CMGC_MAPK_p38_MAPK14_ST	P04637	TP53	Q16539	MAPK14	T81	A84T	84	Missense	distal	3	no	7.344	7.343	EPSD	COSMIC	5.915	Down-regulation
CMGC_MAPK_p38_MAPK14_ST	P04637	TP53	Q16539	MAPK14	T81	A83E	83	Missense	proximal	2	no	7.344	7.573	EPSD	COSMIC	5.915	Up-regulation
CMGC_MAPK_p38_MAPK14_ST	P04637	TP53	Q16539	MAPK14	T81	P85T	85	Missense	distal	4	no	7.344	7.522	EPSD	COSMIC	5.915	Up-regulation
CMGC_MAPK_p38_MAPK14_ST	P04637	TP53	Q16539	MAPK14	T81	A74V	74	Missense	distal	-7	no	7.344	6.526	EPSD	COSMIC	5.915	Down-regulation
CMGC_MAPK_p38_MAPK14_ST	P04637	TP53	Q16539	MAPK14	T81	P75S	75	Missense	distal	-6	no	7.344	7.951	EPSD	COSMIC	5.915	Up-regulation
CMGC_MAPK_p38_MAPK14_ST	P04637	TP53	Q16539	MAPK14	T81	A76V	76	Missense	distal	-5	no	7.344	7.836	EPSD	COSMIC	5.915	Up-regulation
CMGC_MAPK_p38_MAPK14_ST	P04637	TP53	Q16539	MAPK14	T81	P75R	75	Missense	distal	-6	no	7.344	7.844	EPSD	COSMIC	5.915	Up-regulation
CMGC_MAPK_p38_MAPK14_ST	P04637	TP53	Q16539	MAPK14	T81	P87H	87	Missense	distal	6	no	7.344	7.224	EPSD	COSMIC	5.915	Down-regulation
CMGC_MAPK_p38_MAPK14_ST	P04637	TP53	Q16539	MAPK14	T81	P87T	87	Missense	distal	6	no	7.344	7.370	EPSD	COSMIC	5.915	Up-regulation
CMGC_MAPK_p38_MAPK14_ST	P04637	TP53	Q16539	MAPK14	T81	P87S	87	Missense	distal	6	no	7.344	7.332	EPSD	COSMIC	5.915	Down-regulation
CMGC_MAPK_p38_MAPK14_ST	P04637	TP53	Q16539	MAPK14	T81	P87R	87	Missense	distal	6	no	7.344	7.332	EPSD	COSMIC	5.915	Down-regulation
CMGC_MAPK_p38_MAPK14_ST	P04637	TP53	Q16539	MAPK14	T81	P87C	87	Missense	distal	6	no	7.344	7.057	EPSD	COSMIC	5.915	Down-regulation
CMGC_MAPK_p38_MAPK14_ST	P04637	TP53	Q16539	MAPK14	T81	A86E	86	Missense	distal	5	no	7.344	7.945	EPSD	COSMIC	5.915	Up-regulation
CMGC_MAPK_p38_MAPK14_ST	P04637	TP53	Q16539	MAPK14	T81	A86S	86	Missense	distal	5	no	7.344	7.983	EPSD	COSMIC	5.915	Up-regulation
CMGC_MAPK_p38_MAPK14_ST	P04637	TP53	Q16539	MAPK14	T81	A83V	83	Missense	proximal	2	no	7.344	7.180	EPSD	COSMIC	5.915	Down-regulation
CMGC_MAPK_p38_MAPK14_ST	P04637	TP53	Q16539	MAPK14	S127	C124W	124	Missense	distal	-3	no	12.191	12.030	EPSD	COSMIC	5.915	Down-regulation
CMGC_MAPK_p38_MAPK14_ST	P04637	TP53	Q16539	MAPK14	S127	C124F	124	Missense	distal	-3	no	12.191	11.167	EPSD	COSMIC	5.915	Down-regulation
CMGC_MAPK_p38_MAPK14_ST	P04637	TP53	Q16539	MAPK14	S127	C124S	124	Missense	distal	-3	no	12.191	13.874	EPSD	COSMIC	5.915	Up-regulation
CMGC_MAPK_p38_MAPK14_ST	P04637	TP53	Q16539	MAPK14	S127	S127A	127	Missense	central	0	yes	12.191	0.000	EPSD	COSMIC	5.915	Loss
CMGC_MAPK_p38_MAPK14_ST	P04637	TP53	Q16539	MAPK14	S127	S127L	127	Missense	central	0	yes	12.191	0.000	EPSD	COSMIC	5.915	Loss
CMGC_MAPK_p38_MAPK14_ST	P04637	TP53	Q16539	MAPK14	S127	C124T	124	Missense	distal	-3	no	12.191	13.557	EPSD	COSMIC	5.915	Up-regulation
CMGC_MAPK_p38_MAPK14_ST	P04637	TP53	Q16539	MAPK14	S127	S127I	127	Missense	central	0	yes	12.191	0.000	EPSD	COSMIC	5.915	Loss
CMGC_MAPK_p38_MAPK14_ST	P04637	TP53	Q16539	MAPK14	S127	S127G	127	Missense	central	0	yes	12.191	0.000	EPSD	COSMIC	5.915	Loss
CMGC_MAPK_p38_MAPK14_ST	P04637	TP53	Q16539	MAPK14	S127	N131H	131	Missense	distal	4	no	12.191	11.598	EPSD	COSMIC	5.915	Down-regulation
CMGC_MAPK_p38_MAPK14_ST	P04637	TP53	Q16539	MAPK14	S127	N131D	131	Missense	distal	4	no	12.191	11.538	EPSD	COSMIC	5.915	Down-regulation
CMGC_MAPK_p38_MAPK14_ST	P04637	TP53	Q16539	MAPK14	S127	T125I	125	Missense	proximal	-2	no	12.191	12.093	EPSD	COSMIC	5.915	Down-regulation
CMGC_MAPK_p38_MAPK14_ST	P04637	TP53	Q16539	MAPK14	S127	F134I	134	Missense	distal	7	no	12.191	12.328	EPSD	COSMIC	5.915	Up-regulation
CMGC_MAPK_p38_MAPK14_ST	P04637	TP53	Q16539	MAPK14	S127	K120T	120	Missense	distal	-7	no	12.191	12.024	EPSD	COSMIC	5.915	Down-regulation
CMGC_MAPK_p38_MAPK14_ST	P04637	TP53	Q16539	MAPK14	S127	F134S	134	Missense	distal	7	no	12.191	13.061	EPSD	COSMIC	5.915	Up-regulation
CMGC_MAPK_p38_MAPK14_ST	P04637	TP53	Q16539	MAPK14	S127	T125K	125	Missense	proximal	-2	no	12.191	11.620	EPSD	COSMIC	5.915	Down-regulation
CMGC_MAPK_p38_MAPK14_ST	P04637	TP53	Q16539	MAPK14	S127	M133I	133	Missense	distal	6	no	12.191	11.932	EPSD	COSMIC	5.915	Down-regulation
CMGC_MAPK_p38_MAPK14_ST	P04637	TP53	Q16539	MAPK14	S127	N131K	131	Missense	distal	4	no	12.191	12.742	EPSD	COSMIC;CCLE	5.915	Up-regulation
CMGC_MAPK_p38_MAPK14_ST	P04637	TP53	Q16539	MAPK14	S127	P128S	128	Missense	proximal	1	no	12.191	4.907	EPSD	COSMIC	5.915	Loss
CMGC_MAPK_p38_MAPK14_ST	P04637	TP53	Q16539	MAPK14	S127	M133L	133	Missense	distal	6	no	12.191	12.015	EPSD	COSMIC	5.915	Down-regulation
CMGC_MAPK_p38_MAPK14_ST	P04637	TP53	Q16539	MAPK14	S127	A129T	129	Missense	proximal	2	no	12.191	12.219	EPSD	COSMIC	5.915	Up-regulation
CMGC_MAPK_p38_MAPK14_ST	P04637	TP53	Q16539	MAPK14	S127	T123I	123	Missense	distal	-4	no	12.191	12.081	EPSD	COSMIC	5.915	Down-regulation
CMGC_MAPK_p38_MAPK14_ST	P04637	TP53	Q16539	MAPK14	S127	A129G	129	Missense	proximal	2	no	12.191	12.226	EPSD	COSMIC	5.915	Up-regulation
CMGC_MAPK_p38_MAPK14_ST	P04637	TP53	Q16539	MAPK14	S127	K132W	132	Missense	distal	5	no	12.191	11.592	EPSD	COSMIC	5.915	Down-regulation
CMGC_MAPK_p38_MAPK14_ST	P04637	TP53	Q16539	MAPK14	S127	A129V	129	Missense	proximal	2	no	12.191	12.027	EPSD	COSMIC	5.915	Down-regulation
CMGC_MAPK_p38_MAPK14_ST	P04637	TP53	Q16539	MAPK14	S127	P128A	128	Missense	proximal	1	no	12.191	5.873	EPSD	COSMIC	5.915	Loss
CMGC_MAPK_p38_MAPK14_ST	P04637	TP53	Q16539	MAPK14	S127	L130I	130	Missense	distal	3	no	12.191	12.213	EPSD	COSMIC	5.915	Up-regulation
CMGC_MAPK_p38_MAPK14_ST	P04637	TP53	Q16539	MAPK14	S127	S121F	121	Missense	distal	-6	no	12.191	10.427	EPSD	COSMIC	5.915	Down-regulation
CMGC_MAPK_p38_MAPK14_ST	P04637	TP53	Q16539	MAPK14	S127	A129D	129	Missense	proximal	2	no	12.191	11.969	EPSD	COSMIC	5.915	Down-regulation
CMGC_MAPK_p38_MAPK14_ST	P04637	TP53	Q16539	MAPK14	S127	K120Q	120	Missense	distal	-7	no	12.191	11.832	EPSD	COSMIC	5.915	Down-regulation
CMGC_MAPK_p38_MAPK14_ST	P04637	TP53	Q16539	MAPK14	S127	T125S	125	Missense	proximal	-2	no	12.191	12.422	EPSD	COSMIC	5.915	Up-regulation
CMGC_MAPK_p38_MAPK14_ST	P04637	TP53	Q16539	MAPK14	S127	P128L	128	Missense	proximal	1	no	12.191	4.140	EPSD	COSMIC	5.915	Loss
CMGC_MAPK_p38_MAPK14_ST	P04637	TP53	Q16539	MAPK14	S127	V122L	122	Missense	distal	-5	no	12.191	12.317	EPSD	COSMIC	5.915	Up-regulation
CMGC_MAPK_p38_MAPK14_ST	P04637	TP53	Q16539	MAPK14	S127	C124L	124	Missense	distal	-3	no	12.191	12.143	EPSD	COSMIC	5.915	Down-regulation
CMGC_MAPK_p38_MAPK14_ST	P04637	TP53	Q16539	MAPK14	S127	N131T	131	Missense	distal	4	no	12.191	12.446	EPSD	COSMIC	5.915	Up-regulation
CMGC_MAPK_p38_MAPK14_ST	P04637	TP53	Q16539	MAPK14	S127	M133V	133	Missense	distal	6	no	12.191	11.902	EPSD	COSMIC	5.915	Down-regulation
CMGC_MAPK_p38_MAPK14_ST	P04637	TP53	Q16539	MAPK14	S149	W146R	146	Missense	distal	-3	no	5.322	7.679	EPSD	COSMIC	5.915	Gain
CMGC_MAPK_p38_MAPK14_ST	P04637	TP53	Q16539	MAPK14	S149	W146G	146	Missense	distal	-3	no	5.322	6.229	EPSD	COSMIC	5.915	Gain
CMGC_MAPK_p38_MAPK14_ST	P04637	TP53	Q16539	MAPK14	S149	V147E	147	Missense	proximal	-2	no	5.322	6.138	EPSD	COSMIC	5.915	Gain
CMGC_MAPK_p38_MAPK14_ST	P04637	TP53	Q16539	MAPK14	S149	T150A	150	Missense	proximal	1	no	5.322	6.457	EPSD	COSMIC	5.915	Gain
CMGC_MAPK_p38_MAPK14_ST	P04637	TP53	Q16539	MAPK14	T150	P151N	151	Missense	proximal	1	no	7.036	-0.768	EPSD	COSMIC	5.915	Loss
CMGC_MAPK_p38_MAPK14_ST	P04637	TP53	Q16539	MAPK14	T150	P152A	152	Missense	proximal	2	no	7.036	7.149	EPSD	COSMIC	5.915	Up-regulation
CMGC_MAPK_p38_MAPK14_ST	P04637	TP53	Q16539	MAPK14	T150	P152T	152	Missense	proximal	2	no	7.036	7.177	EPSD	COSMIC	5.915	Up-regulation
CMGC_MAPK_p38_MAPK14_ST	P04637	TP53	Q16539	MAPK14	T150	P152H	152	Missense	proximal	2	no	7.036	6.885	EPSD	COSMIC	5.915	Down-regulation
CMGC_MAPK_p38_MAPK14_ST	P04637	TP53	Q16539	MAPK14	T150	P153T	153	Missense	distal	3	no	7.036	7.010	EPSD	COSMIC	5.915	Down-regulation
CMGC_MAPK_p38_MAPK14_ST	P04637	TP53	Q16539	MAPK14	T150	V147I	147	Missense	distal	-3	no	7.036	6.877	EPSD	COSMIC	5.915	Down-regulation
CMGC_MAPK_p38_MAPK14_ST	P04637	TP53	Q16539	MAPK14	T150	P153L	153	Missense	distal	3	no	7.036	7.070	EPSD	COSMIC	5.915	Up-regulation
CMGC_MAPK_p38_MAPK14_ST	P04637	TP53	Q16539	MAPK14	T150	V147D	147	Missense	distal	-3	no	7.036	7.960	EPSD	COSMIC;GDSC;CCLE	5.915	Up-regulation
CMGC_MAPK_p38_MAPK14_ST	P04637	TP53	Q16539	MAPK14	T150	S149P	149	Missense	proximal	-1	no	7.036	7.129	EPSD	COSMIC	5.915	Up-regulation
CMGC_MAPK_p38_MAPK14_ST	P04637	TP53	Q16539	MAPK14	T150	P152K	152	Missense	proximal	2	no	7.036	7.064	EPSD	COSMIC	5.915	Up-regulation
CMGC_MAPK_p38_MAPK14_ST	P04637	TP53	Q16539	MAPK14	T150	P153S	153	Missense	distal	3	no	7.036	6.996	EPSD	COSMIC	5.915	Down-regulation
CMGC_MAPK_p38_MAPK14_ST	P04637	TP53	Q16539	MAPK14	T150	G154C	154	Missense	distal	4	no	7.036	6.117	EPSD	COSMIC	5.915	Down-regulation
CMGC_MAPK_p38_MAPK14_ST	P04637	TP53	Q16539	MAPK14	T150	S149F	149	Missense	proximal	-1	no	7.036	7.278	EPSD	COSMIC	5.915	Up-regulation
CMGC_MAPK_p38_MAPK14_ST	P04637	TP53	Q16539	MAPK14	T150	G154D	154	Missense	distal	4	no	7.036	6.098	EPSD	COSMIC	5.915	Down-regulation
CMGC_MAPK_p38_MAPK14_ST	P04637	TP53	Q16539	MAPK14	T150	V157I	157	Missense	distal	7	no	7.036	6.390	EPSD	COSMIC	5.915	Down-regulation
CMGC_MAPK_p38_MAPK14_ST	P04637	TP53	Q16539	MAPK14	T150	W146R	146	Missense	distal	-4	no	7.036	6.407	EPSD	COSMIC	5.915	Down-regulation
CMGC_MAPK_p38_MAPK14_ST	P04637	TP53	Q16539	MAPK14	T150	Q144R	144	Missense	distal	-6	no	7.036	7.706	EPSD	COSMIC	5.915	Up-regulation
CMGC_MAPK_p38_MAPK14_ST	P04637	TP53	Q16539	MAPK14	T150	D148V	148	Missense	proximal	-2	no	7.036	7.648	EPSD	COSMIC	5.915	Up-regulation
CMGC_MAPK_p38_MAPK14_ST	P04637	TP53	Q16539	MAPK14	T150	S149Y	149	Missense	proximal	-1	no	7.036	7.037	EPSD	COSMIC	5.915	Up-regulation
CMGC_MAPK_p38_MAPK14_ST	P04637	TP53	Q16539	MAPK14	T150	T150I	150	Missense	central	0	yes	7.036	0.000	EPSD	COSMIC	5.915	Loss
CMGC_MAPK_p38_MAPK14_ST	P04637	TP53	Q16539	MAPK14	T150	S149T	149	Missense	proximal	-1	no	7.036	7.152	EPSD	COSMIC	5.915	Up-regulation
CMGC_MAPK_p38_MAPK14_ST	P04637	TP53	Q16539	MAPK14	T150	W146G	146	Missense	distal	-4	no	7.036	6.394	EPSD	COSMIC	5.915	Down-regulation
CMGC_MAPK_p38_MAPK14_ST	P04637	TP53	Q16539	MAPK14	T150	L145M	145	Missense	distal	-5	no	7.036	6.459	EPSD	COSMIC	5.915	Down-regulation
CMGC_MAPK_p38_MAPK14_ST	P04637	TP53	Q16539	MAPK14	T150	V143L	143	Missense	distal	-7	no	7.036	7.461	EPSD	COSMIC	5.915	Up-regulation
CMGC_MAPK_p38_MAPK14_ST	P04637	TP53	Q16539	MAPK14	T150	D148E	148	Missense	proximal	-2	no	7.036	8.464	EPSD	COSMIC	5.915	Up-regulation
CMGC_MAPK_p38_MAPK14_ST	P04637	TP53	Q16539	MAPK14	T150	V147F	147	Missense	distal	-3	no	7.036	6.241	EPSD	COSMIC	5.915	Down-regulation
CMGC_MAPK_p38_MAPK14_ST	P04637	TP53	Q16539	MAPK14	T150	T155A	155	Missense	distal	5	no	7.036	6.564	EPSD	COSMIC	5.915	Down-regulation
CMGC_MAPK_p38_MAPK14_ST	P04637	TP53	Q16539	MAPK14	T150	V147E	147	Missense	distal	-3	no	7.036	8.166	EPSD	COSMIC	5.915	Up-regulation
CMGC_MAPK_p38_MAPK14_ST	P04637	TP53	Q16539	MAPK14	T150	G154I	154	Missense	distal	4	no	7.036	6.479	EPSD	COSMIC	5.915	Down-regulation
CMGC_MAPK_p38_MAPK14_ST	P04637	TP53	Q16539	MAPK14	T150	D148G	148	Missense	proximal	-2	no	7.036	7.787	EPSD	COSMIC	5.915	Up-regulation
CMGC_MAPK_p38_MAPK14_ST	P04637	TP53	Q16539	MAPK14	T150	Q144K	144	Missense	distal	-6	no	7.036	7.227	EPSD	COSMIC	5.915	Up-regulation
CMGC_MAPK_p38_MAPK14_ST	P04637	TP53	Q16539	MAPK14	T150	V147A	147	Missense	distal	-3	no	7.036	8.537	EPSD	COSMIC	5.915	Up-regulation
CMGC_MAPK_p38_MAPK14_ST	P04637	TP53	Q16539	MAPK14	T150	L145V	145	Missense	distal	-5	no	7.036	6.910	EPSD	COSMIC	5.915	Down-regulation
CMGC_MAPK_p38_MAPK14_ST	P04637	TP53	Q16539	MAPK14	T150	T150K	150	Missense	central	0	yes	7.036	0.000	EPSD	COSMIC	5.915	Loss
CMGC_MAPK_p38_MAPK14_ST	P04637	TP53	Q16539	MAPK14	T150	P153H	153	Missense	distal	3	no	7.036	7.095	EPSD	COSMIC	5.915	Up-regulation
CMGC_MAPK_p38_MAPK14_ST	P04637	TP53	Q16539	MAPK14	T150	V157E	157	Missense	distal	7	no	7.036	7.340	EPSD	COSMIC	5.915	Up-regulation
CMGC_MAPK_p38_MAPK14_ST	P04637	TP53	Q16539	MAPK14	T150	T155S	155	Missense	distal	5	no	7.036	7.203	EPSD	COSMIC;CCLE	5.915	Up-regulation
CMGC_MAPK_p38_MAPK14_ST	P04637	TP53	Q16539	MAPK14	T150	D148H	148	Missense	proximal	-2	no	7.036	6.459	EPSD	COSMIC	5.915	Down-regulation
CMGC_MAPK_p38_MAPK14_ST	P04637	TP53	Q16539	MAPK14	T150	P153A	153	Missense	distal	3	no	7.036	7.010	EPSD	COSMIC	5.915	Down-regulation
CMGC_MAPK_p38_MAPK14_ST	P04637	TP53	Q16539	MAPK14	T150	T150R	150	Missense	central	0	yes	7.036	0.000	EPSD	COSMIC	5.915	Loss
CMGC_MAPK_p38_MAPK14_ST	P04637	TP53	Q16539	MAPK14	T150	T155L	155	Missense	distal	5	no	7.036	6.255	EPSD	COSMIC	5.915	Down-regulation
CMGC_MAPK_p38_MAPK14_ST	P04637	TP53	Q16539	MAPK14	T150	G154A	154	Missense	distal	4	no	7.036	6.962	EPSD	COSMIC	5.915	Down-regulation
CMGC_MAPK_p38_MAPK14_ST	P04637	TP53	Q16539	MAPK14	T150	T150A	150	Missense	central	0	yes	7.036	0.000	EPSD	COSMIC	5.915	Loss
CMGC_MAPK_p38_MAPK14_ST	P04637	TP53	Q16539	MAPK14	T150	W146C	146	Missense	distal	-4	no	7.036	6.857	EPSD	COSMIC	5.915	Down-regulation
CMGC_MAPK_p38_MAPK14_ST	P04637	TP53	Q16539	MAPK14	T150	P153F	153	Missense	distal	3	no	7.036	7.104	EPSD	COSMIC	5.915	Up-regulation
CMGC_MAPK_p38_MAPK14_ST	P04637	TP53	Q16539	MAPK14	T150	D148Y	148	Missense	proximal	-2	no	7.036	8.239	EPSD	COSMIC	5.915	Up-regulation
CMGC_MAPK_p38_MAPK14_ST	P04637	TP53	Q16539	MAPK14	T150	G154R	154	Missense	distal	4	no	7.036	6.551	EPSD	COSMIC	5.915	Down-regulation
CMGC_MAPK_p38_MAPK14_ST	P04637	TP53	Q16539	MAPK14	T211	R209Q	209	Missense	proximal	-2	no	6.953	6.627	EPSD	COSMIC	5.915	Down-regulation
CMGC_MAPK_p38_MAPK14_ST	P04637	TP53	Q16539	MAPK14	T211	R209W	209	Missense	proximal	-2	no	6.953	6.427	EPSD	COSMIC	5.915	Down-regulation
CMGC_MAPK_p38_MAPK14_ST	P04637	TP53	Q16539	MAPK14	T211	R209P	209	Missense	proximal	-2	no	6.953	7.642	EPSD	COSMIC	5.915	Up-regulation
CMGC_MAPK_p38_MAPK14_ST	P04637	TP53	Q16539	MAPK14	T211	R209L	209	Missense	proximal	-2	no	6.953	6.262	EPSD	COSMIC	5.915	Down-regulation
CMGC_MAPK_p38_MAPK14_ST	P04637	TP53	Q16539	MAPK14	T211	R209G	209	Missense	proximal	-2	no	6.953	6.703	EPSD	COSMIC	5.915	Down-regulation
CMGC_MAPK_p38_MAPK14_ST	P04637	TP53	Q16539	MAPK14	T211	R209C	209	Missense	proximal	-2	no	6.953	6.018	EPSD	COSMIC	5.915	Down-regulation
CMGC_MAPK_p38_MAPK14_ST	P04637	TP53	Q16539	MAPK14	T211	E204K	204	Missense	distal	-7	no	6.953	6.899	EPSD	COSMIC	5.915	Down-regulation
CMGC_MAPK_p38_MAPK14_ST	P04637	TP53	Q16539	MAPK14	T211	V216A	216	Missense	distal	5	no	6.953	6.972	EPSD	COSMIC	5.915	Up-regulation
CMGC_MAPK_p38_MAPK14_ST	P04637	TP53	Q16539	MAPK14	T211	V217A	217	Missense	distal	6	no	6.953	7.249	EPSD	COSMIC	5.915	Up-regulation
CMGC_MAPK_p38_MAPK14_ST	P04637	TP53	Q16539	MAPK14	T211	E204G	204	Missense	distal	-7	no	6.953	6.735	EPSD	COSMIC	5.915	Down-regulation
CMGC_MAPK_p38_MAPK14_ST	P04637	TP53	Q16539	MAPK14	T211	V218M	218	Missense	distal	7	no	6.953	6.910	EPSD	COSMIC	5.915	Down-regulation
CMGC_MAPK_p38_MAPK14_ST	P04637	TP53	Q16539	MAPK14	T211	D208E	208	Missense	distal	-3	no	6.953	7.159	EPSD	COSMIC	5.915	Up-regulation
CMGC_MAPK_p38_MAPK14_ST	P04637	TP53	Q16539	MAPK14	T211	F212L	212	Missense	proximal	1	no	6.953	4.906	EPSD	COSMIC	5.915	Loss
CMGC_MAPK_p38_MAPK14_ST	P04637	TP53	Q16539	MAPK14	T211	H214Q	214	Missense	distal	3	no	6.953	6.923	EPSD	COSMIC	5.915	Down-regulation
CMGC_MAPK_p38_MAPK14_ST	P04637	TP53	Q16539	MAPK14	T211	R213W	213	Missense	proximal	2	no	6.953	6.455	EPSD	COSMIC	5.915	Down-regulation
CMGC_MAPK_p38_MAPK14_ST	P04637	TP53	Q16539	MAPK14	T211	N210D	210	Missense	proximal	-1	no	6.953	7.139	EPSD	COSMIC	5.915	Up-regulation
CMGC_MAPK_p38_MAPK14_ST	P04637	TP53	Q16539	MAPK14	T211	V218A	218	Missense	distal	7	no	6.953	7.062	EPSD	COSMIC	5.915	Up-regulation
CMGC_MAPK_p38_MAPK14_ST	P04637	TP53	Q16539	MAPK14	T211	S215C	215	Missense	distal	4	no	6.953	5.802	EPSD	COSMIC;GDSC;CCLE	5.915	Loss
CMGC_MAPK_p38_MAPK14_ST	P04637	TP53	Q16539	MAPK14	T211	V218L	218	Missense	distal	7	no	6.953	6.655	EPSD	COSMIC;GDSC;CCLE	5.915	Down-regulation
CMGC_MAPK_p38_MAPK14_ST	P04637	TP53	Q16539	MAPK14	T211	E204V	204	Missense	distal	-7	no	6.953	6.098	EPSD	COSMIC	5.915	Down-regulation
CMGC_MAPK_p38_MAPK14_ST	P04637	TP53	Q16539	MAPK14	T211	T211N	211	Missense	central	0	yes	6.953	0.000	EPSD	COSMIC	5.915	Loss
CMGC_MAPK_p38_MAPK14_ST	P04637	TP53	Q16539	MAPK14	T211	N210S	210	Missense	proximal	-1	no	6.953	6.882	EPSD	COSMIC	5.915	Down-regulation
CMGC_MAPK_p38_MAPK14_ST	P04637	TP53	Q16539	MAPK14	T211	D207G	207	Missense	distal	-4	no	6.953	6.458	EPSD	COSMIC	5.915	Down-regulation
CMGC_MAPK_p38_MAPK14_ST	P04637	TP53	Q16539	MAPK14	T211	F212I	212	Missense	proximal	1	no	6.953	5.278	EPSD	COSMIC	5.915	Loss
CMGC_MAPK_p38_MAPK14_ST	P04637	TP53	Q16539	MAPK14	T211	D207A	207	Missense	distal	-4	no	6.953	6.501	EPSD	COSMIC	5.915	Down-regulation
CMGC_MAPK_p38_MAPK14_ST	P04637	TP53	Q16539	MAPK14	T211	N210H	210	Missense	proximal	-1	no	6.953	6.930	EPSD	COSMIC	5.915	Down-regulation
CMGC_MAPK_p38_MAPK14_ST	P04637	TP53	Q16539	MAPK14	T211	V217E	217	Missense	distal	6	no	6.953	7.274	EPSD	COSMIC	5.915	Up-regulation
CMGC_MAPK_p38_MAPK14_ST	P04637	TP53	Q16539	MAPK14	T211	R209T	209	Missense	proximal	-2	no	6.953	6.922	EPSD	COSMIC	5.915	Down-regulation
CMGC_MAPK_p38_MAPK14_ST	P04637	TP53	Q16539	MAPK14	T211	D207Y	207	Missense	distal	-4	no	6.953	6.456	EPSD	COSMIC	5.915	Down-regulation
CMGC_MAPK_p38_MAPK14_ST	P04637	TP53	Q16539	MAPK14	T211	D208Y	208	Missense	distal	-3	no	6.953	7.047	EPSD	COSMIC	5.915	Up-regulation
CMGC_MAPK_p38_MAPK14_ST	P04637	TP53	Q16539	MAPK14	T211	V217L	217	Missense	distal	6	no	6.953	7.067	EPSD	COSMIC	5.915	Up-regulation
CMGC_MAPK_p38_MAPK14_ST	P04637	TP53	Q16539	MAPK14	T211	L206F	206	Missense	distal	-5	no	6.953	7.009	EPSD	COSMIC	5.915	Up-regulation
CMGC_MAPK_p38_MAPK14_ST	P04637	TP53	Q16539	MAPK14	T211	E204A	204	Missense	distal	-7	no	6.953	6.916	EPSD	COSMIC	5.915	Down-regulation
CMGC_MAPK_p38_MAPK14_ST	P04637	TP53	Q16539	MAPK14	T211	D208H	208	Missense	distal	-3	no	6.953	6.701	EPSD	COSMIC	5.915	Down-regulation
CMGC_MAPK_p38_MAPK14_ST	P04637	TP53	Q16539	MAPK14	T211	V217M	217	Missense	distal	6	no	6.953	7.243	EPSD	COSMIC	5.915	Up-regulation
CMGC_MAPK_p38_MAPK14_ST	P04637	TP53	Q16539	MAPK14	T211	D207E	207	Missense	distal	-4	no	6.953	6.161	EPSD	COSMIC	5.915	Down-regulation
CMGC_MAPK_p38_MAPK14_ST	P04637	TP53	Q16539	MAPK14	T211	N210T	210	Missense	proximal	-1	no	6.953	6.998	EPSD	COSMIC	5.915	Up-regulation
CMGC_MAPK_p38_MAPK14_ST	P04637	TP53	Q16539	MAPK14	T211	N210K	210	Missense	proximal	-1	no	6.953	6.856	EPSD	COSMIC	5.915	Down-regulation
CMGC_MAPK_p38_MAPK14_ST	P04637	TP53	Q16539	MAPK14	T211	F212S	212	Missense	proximal	1	no	6.953	5.673	EPSD	COSMIC	5.915	Loss
CMGC_MAPK_p38_MAPK14_ST	P04637	TP53	Q16539	MAPK14	T211	H214P	214	Missense	distal	3	no	6.953	6.895	EPSD	COSMIC	5.915	Down-regulation
CMGC_MAPK_p38_MAPK14_ST	P04637	TP53	Q16539	MAPK14	T211	D208I	208	Missense	distal	-3	no	6.953	5.870	EPSD	COSMIC	5.915	Loss
CMGC_MAPK_p38_MAPK14_ST	P04637	TP53	Q16539	MAPK14	T211	F212Y	212	Missense	proximal	1	no	6.953	5.680	EPSD	COSMIC	5.915	Loss
CMGC_MAPK_p38_MAPK14_ST	P04637	TP53	Q16539	MAPK14	T211	H214A	214	Missense	distal	3	no	6.953	6.869	EPSD	COSMIC	5.915	Down-regulation
CMGC_MAPK_p38_MAPK14_ST	P04637	TP53	Q16539	MAPK14	S314	S315P	315	Missense	proximal	1	no	1.932	9.216	EPSD	COSMIC	5.915	Gain
CMGC_MAPK_p38_MAPK14_ST	P04637	TP53	Q16539	MAPK14	S315	N310T	310	Missense	distal	-5	no	10.517	10.495	EPSD	COSMIC	5.915	Down-regulation
CMGC_MAPK_p38_MAPK14_ST	P04637	TP53	Q16539	MAPK14	S315	Q317R	317	Missense	proximal	2	no	10.517	10.944	EPSD	COSMIC	5.915	Up-regulation
CMGC_MAPK_p38_MAPK14_ST	P04637	TP53	Q16539	MAPK14	S315	P309S	309	Missense	distal	-6	no	10.517	11.124	EPSD	COSMIC;GDSC;CCLE	5.915	Up-regulation
CMGC_MAPK_p38_MAPK14_ST	P04637	TP53	Q16539	MAPK14	S315	K319E	319	Missense	distal	4	no	10.517	10.983	EPSD	COSMIC	5.915	Up-regulation
CMGC_MAPK_p38_MAPK14_ST	P04637	TP53	Q16539	MAPK14	S315	P322L	322	Missense	distal	7	no	10.517	10.355	EPSD	COSMIC	5.915	Down-regulation
CMGC_MAPK_p38_MAPK14_ST	P04637	TP53	Q16539	MAPK14	S315	K320N	320	Missense	distal	5	no	10.517	10.787	EPSD	COSMIC;GDSC;CCLE	5.915	Up-regulation
CMGC_MAPK_p38_MAPK14_ST	P04637	TP53	Q16539	MAPK14	S315	N310L	310	Missense	distal	-5	no	10.517	10.783	EPSD	COSMIC	5.915	Up-regulation
CMGC_MAPK_p38_MAPK14_ST	P04637	TP53	Q16539	MAPK14	S315	T312S	312	Missense	distal	-3	no	10.517	10.835	EPSD	COSMIC	5.915	Up-regulation
CMGC_MAPK_p38_MAPK14_ST	P04637	TP53	Q16539	MAPK14	S315	N311Y	311	Missense	distal	-4	no	10.517	10.440	EPSD	COSMIC	5.915	Down-regulation
CMGC_MAPK_p38_MAPK14_ST	P04637	TP53	Q16539	MAPK14	S315	P322R	322	Missense	distal	7	no	10.517	10.774	EPSD	COSMIC	5.915	Up-regulation
CMGC_MAPK_p38_MAPK14_ST	P04637	TP53	Q16539	MAPK14	S315	N311K	311	Missense	distal	-4	no	10.517	10.371	EPSD	COSMIC	5.915	Down-regulation
CMGC_MAPK_p38_MAPK14_ST	P04637	TP53	Q16539	MAPK14	S315	Q317K	317	Missense	proximal	2	no	10.517	10.740	EPSD	COSMIC	5.915	Up-regulation
CMGC_MAPK_p38_MAPK14_ST	P04637	TP53	Q16539	MAPK14	S315	S315P	315	Missense	central	0	yes	10.517	0.000	EPSD	COSMIC	5.915	Loss
CMGC_MAPK_p38_MAPK14_ST	P04637	TP53	Q16539	MAPK14	S315	N310H	310	Missense	distal	-5	no	10.517	10.815	EPSD	COSMIC	5.915	Up-regulation
CMGC_MAPK_p38_MAPK14_ST	P04637	TP53	Q16539	MAPK14	S315	S314C	314	Missense	proximal	-1	no	10.517	10.673	EPSD	COSMIC	5.915	Up-regulation
CMGC_MAPK_p38_MAPK14_ST	P04637	TP53	Q16539	MAPK14	S315	P318A	318	Missense	distal	3	no	10.517	10.492	EPSD	COSMIC	5.915	Down-regulation
CMGC_MAPK_p38_MAPK14_ST	P04637	TP53	Q16539	MAPK14	S315	P316L	316	Missense	proximal	1	no	10.517	2.467	EPSD	COSMIC	5.915	Loss
CMGC_MAPK_p38_MAPK14_ST	P04637	TP53	Q16539	MAPK14	S315	L308M	308	Missense	distal	-7	no	10.517	10.782	EPSD	COSMIC	5.915	Up-regulation
CMGC_MAPK_p38_MAPK14_ST	P04637	TP53	Q16539	MAPK14	S315	S313C	313	Missense	proximal	-2	no	10.517	9.382	EPSD	COSMIC	5.915	Down-regulation
CMGC_MAPK_p38_MAPK14_ST	P04637	TP53	Q16539	MAPK14	S315	N311H	311	Missense	distal	-4	no	10.517	10.666	EPSD	COSMIC	5.915	Up-regulation
CMGC_MAPK_p38_MAPK14_ST	P04637	TP53	Q16539	MAPK14	S315	L308V	308	Missense	distal	-7	no	10.517	10.093	EPSD	COSMIC	5.915	Down-regulation
CMGC_MAPK_p38_MAPK14_ST	P04637	TP53	Q16539	MAPK14	S315	S314F	314	Missense	proximal	-1	no	10.517	10.760	EPSD	COSMIC	5.915	Up-regulation
CMGC_MAPK_p38_MAPK14_ST	P04637	TP53	Q16539	MAPK14	S315	K319R	319	Missense	distal	4	no	10.517	9.766	EPSD	COSMIC	5.915	Down-regulation
CMGC_MAPK_p38_MAPK14_ST	P04637	TP53	Q16539	MAPK14	S315	T312A	312	Missense	distal	-3	no	10.517	10.423	EPSD	COSMIC	5.915	Down-regulation
CMGC_MAPK_p38_MAPK14_ST	P04637	TP53	Q16539	MAPK14	S315	N310D	310	Missense	distal	-5	no	10.517	10.677	EPSD	COSMIC	5.915	Up-regulation
CMGC_MAPK_p38_MAPK14_ST	P04637	TP53	Q16539	MAPK14	S315	N311D	311	Missense	distal	-4	no	10.517	10.937	EPSD	COSMIC	5.915	Up-regulation
CMGC_MAPK_p38_MAPK14_ST	P04637	TP53	Q16539	MAPK14	S315	P309R	309	Missense	distal	-6	no	10.517	11.018	EPSD	COSMIC	5.915	Up-regulation
CMGC_MAPK_p38_MAPK14_ST	P04637	TP53	Q16539	MAPK14	S315	S313N	313	Missense	proximal	-2	no	10.517	9.831	EPSD	COSMIC	5.915	Down-regulation
CMGC_MAPK_p38_MAPK14_ST	P04637	TP53	Q16539	MAPK14	S315	Q317P	317	Missense	proximal	2	no	10.517	10.712	EPSD	COSMIC	5.915	Up-regulation
CMGC_MAPK_p38_MAPK14_ST	P04637	TP53	Q16539	MAPK14	S315	P316S	316	Missense	proximal	1	no	10.517	3.234	EPSD	COSMIC	5.915	Loss
CMGC_MAPK_p38_MAPK14_ST	P04637	TP53	Q16539	MAPK14	S366	S367F	367	Missense	proximal	1	no	6.617	7.897	EPSD	COSMIC	5.915	Up-regulation
CMGC_MAPK_p38_MAPK14_ST	P04637	TP53	Q16539	MAPK14	S366	K370N	370	Missense	distal	4	no	6.617	6.066	EPSD	COSMIC	5.915	Down-regulation
CMGC_MAPK_p38_MAPK14_ST	P04637	TP53	Q16539	MAPK14	S366	G361E	361	Missense	distal	-5	no	6.617	5.985	EPSD	COSMIC	5.915	Down-regulation
CMGC_MAPK_p38_MAPK14_ST	P04637	TP53	Q16539	MAPK14	S366	P359S	359	Missense	distal	-7	no	6.617	6.704	EPSD	COSMIC	5.915	Up-regulation
CMGC_MAPK_p38_MAPK14_ST	P04637	TP53	Q16539	MAPK14	S366	A364D	364	Missense	proximal	-2	no	6.617	5.590	EPSD	COSMIC	5.915	Loss
CMGC_MAPK_p38_MAPK14_ST	P04637	TP53	Q16539	MAPK14	S366	H365Y	365	Missense	proximal	-1	no	6.617	6.570	EPSD	COSMIC	5.915	Down-regulation
CMGC_MAPK_p38_MAPK14_ST	P04637	TP53	Q16539	MAPK14	S366	G360A	360	Missense	distal	-6	no	6.617	6.555	EPSD	COSMIC	5.915	Down-regulation
CMGC_MAPK_p38_MAPK14_ST	P04637	TP53	Q16539	MAPK14	S366	A364T	364	Missense	proximal	-2	no	6.617	6.559	EPSD	COSMIC	5.915	Down-regulation
CMGC_MAPK_p38_MAPK14_ST	P04637	TP53	Q16539	MAPK14	S366	S366A	366	Missense	central	0	yes	6.617	0.000	EPSD	COSMIC	5.915	Loss
CMGC_MAPK_p38_MAPK14_ST	P04637	TP53	Q16539	MAPK14	S366	G361R	361	Missense	distal	-5	no	6.617	6.454	EPSD	COSMIC	5.915	Down-regulation
CMGC_MAPK_p38_MAPK14_ST	P04637	TP53	Q16539	MAPK14	S366	K370Q	370	Missense	distal	4	no	6.617	5.661	EPSD	COSMIC	5.915	Loss
CMGC_MAPK_p38_MAPK14_ST	P04637	TP53	Q16539	MAPK14	S366	K373R	373	Missense	distal	7	no	6.617	7.140	EPSD	COSMIC	5.915	Up-regulation
CMGC_MAPK_p38_MAPK14_ST	P04637	TP53	Q16539	MAPK14	S366	S371P	371	Missense	distal	5	no	6.617	6.166	EPSD	COSMIC	5.915	Down-regulation
CMGC_MAPK_p38_MAPK14_ST	P04637	TP53	Q16539	MAPK14	T377	S378F	378	Missense	proximal	1	no	4.829	6.109	EPSD	COSMIC	5.915	Gain
CMGC_MAPK_p38_MAPK14_ST	P04637	TP53	Q16539	MAPK14	S378	R379P	379	Missense	proximal	1	no	0.325	8.260	EPSD	COSMIC	5.915	Gain
CMGC_MAPK_p38_MAPK14_ST	Q9UIG0	BAZ1B	Q16539	MAPK14	S197	T203S	203	Missense	distal	6	no	10.765	10.727	EPSD	COSMIC	5.915	Down-regulation
CMGC_MAPK_p38_MAPK14_ST	Q9UIG0	BAZ1B	Q16539	MAPK14	S204	L205F	205	Missense	proximal	1	no	4.846	6.893	EPSD	COSMIC	5.915	Gain
CMGC_MAPK_p38_MAPK14_ST	Q9UIG0	BAZ1B	Q16539	MAPK14	T266	A270E	270	Missense	distal	4	no	5.926	6.731	EPSD	COSMIC	5.915	Up-regulation
CMGC_MAPK_p38_MAPK14_ST	Q9UIG0	BAZ1B	Q16539	MAPK14	S349	S347G	347	Missense	proximal	-2	no	8.838	8.388	EPSD	COSMIC	5.915	Down-regulation
CMGC_MAPK_p38_MAPK14_ST	Q9UIG0	BAZ1B	Q16539	MAPK14	S361	P362L	362	Missense	proximal	1	no	11.743	3.692	EPSD	COSMIC	5.915	Loss
CMGC_MAPK_p38_MAPK14_ST	Q9UIG0	BAZ1B	Q16539	MAPK14	S423	L428M	428	Missense	distal	5	no	9.033	9.501	EPSD	COSMIC	5.915	Up-regulation
CMGC_MAPK_p38_MAPK14_ST	Q9UIG0	BAZ1B	Q16539	MAPK14	T430	K432Q	432	Missense	proximal	2	no	10.147	9.924	EPSD	COSMIC	5.915	Down-regulation
CMGC_MAPK_p38_MAPK14_ST	Q9UIG0	BAZ1B	Q16539	MAPK14	T430	L428M	428	Missense	proximal	-2	no	10.147	10.715	EPSD	COSMIC	5.915	Up-regulation
CMGC_MAPK_p38_MAPK14_ST	Q9UIG0	BAZ1B	Q16539	MAPK14	T430	K432I	432	Missense	proximal	2	no	10.147	10.017	EPSD	COSMIC;GDSC;CCLE	5.915	Down-regulation
CMGC_MAPK_p38_MAPK14_ST	Q9UIG0	BAZ1B	Q16539	MAPK14	S457	P461S	461	Missense	distal	4	no	6.820	7.260	EPSD	COSMIC	5.915	Up-regulation
CMGC_MAPK_p38_MAPK14_ST	Q9UIG0	BAZ1B	Q16539	MAPK14	S457	R455W	455	Missense	proximal	-2	no	6.820	6.294	EPSD	COSMIC	5.915	Down-regulation
CMGC_MAPK_p38_MAPK14_ST	Q9UIG0	BAZ1B	Q16539	MAPK14	T460	P461S	461	Missense	proximal	1	no	14.838	7.554	EPSD	COSMIC	5.915	Down-regulation
CMGC_MAPK_p38_MAPK14_ST	Q9UIG0	BAZ1B	Q16539	MAPK14	T460	R455W	455	Missense	distal	-5	no	14.838	15.583	EPSD	COSMIC	5.915	Up-regulation
CMGC_MAPK_p38_MAPK14_ST	Q9UIG0	BAZ1B	Q16539	MAPK14	S699	E706K	706	Missense	distal	7	no	6.660	5.954	EPSD	COSMIC	5.915	Down-regulation
CMGC_MAPK_p38_MAPK14_ST	Q9UIG0	BAZ1B	Q16539	MAPK14	S699	D700E	700	Missense	proximal	1	no	6.660	6.332	EPSD	COSMIC	5.915	Down-regulation
CMGC_MAPK_p38_MAPK14_ST	Q9UIG0	BAZ1B	Q16539	MAPK14	S699	R698S	698	Missense	proximal	-1	no	6.660	6.768	EPSD	COSMIC	5.915	Up-regulation
CMGC_MAPK_p38_MAPK14_ST	Q9UIG0	BAZ1B	Q16539	MAPK14	S1127	E1131K	1131	Missense	distal	4	no	10.837	10.371	EPSD	COSMIC	5.915	Down-regulation
CMGC_MAPK_p38_MAPK14_ST	Q9UIG0	BAZ1B	Q16539	MAPK14	S1342	E1349Q	1349	Missense	distal	7	no	6.584	6.207	EPSD	COSMIC;GDSC;CCLE	5.915	Down-regulation
CMGC_MAPK_p38_MAPK14_ST	Q9UIG0	BAZ1B	Q16539	MAPK14	S1361	R1359C	1359	Missense	proximal	-2	no	6.703	5.768	EPSD	COSMIC;GDSC;CCLE	5.915	Loss
CMGC_MAPK_p38_MAPK14_ST	Q15717	ELAVL1	Q16539	MAPK14	S100	A96V	96	Missense	distal	-4	no	6.812	7.094	EPSD	COSMIC	5.915	Up-regulation
CMGC_MAPK_p38_MAPK14_ST	Q15717	ELAVL1	Q16539	MAPK14	S100	R97L	97	Missense	distal	-3	no	6.812	4.568	EPSD	COSMIC	5.915	Loss
CMGC_MAPK_p38_MAPK14_ST	Q15717	ELAVL1	Q16539	MAPK14	S100	E101G	101	Missense	proximal	1	no	6.812	6.776	EPSD	COSMIC	5.915	Down-regulation
CMGC_MAPK_p38_MAPK14_ST	Q15717	ELAVL1	Q16539	MAPK14	S202	R206W	206	Missense	distal	4	no	7.397	6.122	EPSD	COSMIC	5.915	Down-regulation
CMGC_MAPK_p38_MAPK14_ST	Q15717	ELAVL1	Q16539	MAPK14	S202	G208R	208	Missense	distal	6	no	7.397	7.275	EPSD	COSMIC	5.915	Down-regulation
CMGC_MAPK_p38_MAPK14_ST	Q15717	ELAVL1	Q16539	MAPK14	S202	G208V	208	Missense	distal	6	no	7.397	7.035	EPSD	COSMIC	5.915	Down-regulation
CMGC_MAPK_p38_MAPK14_ST	Q15717	ELAVL1	Q16539	MAPK14	S202	L195F	195	Missense	distal	-7	no	7.397	6.931	EPSD	COSMIC	5.915	Down-regulation
CMGC_MAPK_p38_MAPK14_ST	Q15717	ELAVL1	Q16539	MAPK14	S221	V225I	225	Missense	distal	4	no	8.107	8.058	EPSD	COSMIC	5.915	Down-regulation
CMGC_MAPK_p38_MAPK14_ST	P31645	SLC6A4	Q16539	MAPK14	S52	Y47C	47	Missense	distal	-5	no	9.852	10.105	EPSD	COSMIC	5.915	Up-regulation
CMGC_MAPK_p38_MAPK14_ST	P31645	SLC6A4	Q16539	MAPK14	S52	G56E	56	Missense	distal	4	no	9.852	10.584	EPSD	COSMIC	5.915	Up-regulation
CMGC_MAPK_p38_MAPK14_ST	P31645	SLC6A4	Q16539	MAPK14	T616	G623R	623	Missense	distal	7	no	11.292	11.470	PhosphoSitePlus	COSMIC	5.915	Up-regulation
CMGC_MAPK_p38_MAPK14_ST	Q9NQU5	PAK6	Q16539	MAPK14	S132	D139N	139	Missense	distal	7	no	11.251	10.929	EPSD	COSMIC	5.915	Down-regulation
CMGC_MAPK_p38_MAPK14_ST	Q9NQU5	PAK6	Q16539	MAPK14	S132	Y129F	129	Missense	distal	-3	no	11.251	9.438	EPSD	COSMIC;CCLE	5.915	Down-regulation
CMGC_MAPK_p38_MAPK14_ST	Q9NQU5	PAK6	Q16539	MAPK14	S132	P133L	133	Missense	proximal	1	no	11.251	3.200	EPSD	COSMIC;GDSC;CCLE	5.915	Loss
CMGC_MAPK_p38_MAPK14_ST	Q9NQU5	PAK6	Q16539	MAPK14	S135	D139N	139	Missense	distal	4	no	6.300	6.954	EPSD	COSMIC	5.915	Up-regulation
CMGC_MAPK_p38_MAPK14_ST	Q9NQU5	PAK6	Q16539	MAPK14	S135	Y129F	129	Missense	distal	-6	no	6.300	5.302	EPSD	COSMIC;CCLE	5.915	Loss
CMGC_MAPK_p38_MAPK14_ST	Q9NQU5	PAK6	Q16539	MAPK14	S135	P133L	133	Missense	proximal	-2	no	6.300	4.920	EPSD	COSMIC;GDSC;CCLE	5.915	Loss
CMGC_MAPK_p38_MAPK14_ST	Q9NQU5	PAK6	Q16539	MAPK14	S165	R167Q	167	Missense	proximal	2	no	8.810	8.384	PhosphoSitePlus	COSMIC	5.915	Down-regulation
CMGC_MAPK_p38_MAPK14_ST	Q9NQU5	PAK6	Q16539	MAPK14	S202	P208L	208	Missense	distal	6	no	11.366	11.227	EPSD	COSMIC	5.915	Down-regulation
CMGC_MAPK_p38_MAPK14_ST	Q9NQU5	PAK6	Q16539	MAPK14	S207	P208L	208	Missense	proximal	1	no	9.271	1.221	EPSD	COSMIC	5.915	Loss
CMGC_MAPK_p38_MAPK14_ST	Q9NQU5	PAK6	Q16539	MAPK14	S246	R240W	240	Missense	distal	-6	no	15.109	13.791	EPSD	COSMIC	5.915	Down-regulation
CMGC_MAPK_p38_MAPK14_ST	Q9NQU5	PAK6	Q16539	MAPK14	S246	E244K	244	Missense	proximal	-2	no	15.109	14.079	EPSD	COSMIC	5.915	Down-regulation
CMGC_MAPK_p38_MAPK14_ST	Q9NQU5	PAK6	Q16539	MAPK14	S246	P249L	249	Missense	distal	3	no	15.109	15.143	EPSD	COSMIC	5.915	Up-regulation
CMGC_MAPK_p38_MAPK14_ST	Q9NQU5	PAK6	Q16539	MAPK14	S248	E244K	244	Missense	distal	-4	no	11.306	11.531	EPSD	COSMIC	5.915	Up-regulation
CMGC_MAPK_p38_MAPK14_ST	Q9NQU5	PAK6	Q16539	MAPK14	S248	P249L	249	Missense	proximal	1	no	11.306	3.255	EPSD	COSMIC	5.915	Loss
CMGC_MAPK_p38_MAPK14_ST	Q9NQU5	PAK6	Q16539	MAPK14	T317	T317I	317	Missense	central	0	yes	6.360	0.000	EPSD	COSMIC	5.915	Loss
CMGC_MAPK_p38_MAPK14_ST	Q9NQU5	PAK6	Q16539	MAPK14	T317	S319C	319	Missense	proximal	2	no	6.360	5.947	EPSD	COSMIC	5.915	Down-regulation
CMGC_MAPK_p38_MAPK14_ST	Q9NQU5	PAK6	Q16539	MAPK14	S319	T317I	317	Missense	proximal	-2	no	10.984	10.885	EPSD	COSMIC	5.915	Down-regulation
CMGC_MAPK_p38_MAPK14_ST	Q9NQU5	PAK6	Q16539	MAPK14	S319	S319C	319	Missense	central	0	yes	10.984	0.000	EPSD	COSMIC	5.915	Loss
CMGC_MAPK_p38_MAPK14_ST	Q9NQU5	PAK6	Q16539	MAPK14	S328	R334C	334	Missense	distal	6	no	10.654	10.379	EPSD	COSMIC	5.915	Down-regulation
CMGC_MAPK_p38_MAPK14_ST	Q9NQU5	PAK6	Q16539	MAPK14	S347	T354P	354	Missense	distal	7	no	11.402	11.501	EPSD	COSMIC	5.915	Up-regulation
CMGC_MAPK_p38_MAPK14_ST	Q9NQU5	PAK6	Q16539	MAPK14	S347	S347F	347	Missense	central	0	yes	11.402	0.000	EPSD	COSMIC	5.915	Loss
CMGC_MAPK_p38_MAPK14_ST	Q9NQU5	PAK6	Q16539	MAPK14	S347	P348S	348	Missense	proximal	1	no	11.402	4.118	EPSD	COSMIC	5.915	Loss
CMGC_MAPK_p38_MAPK14_ST	Q9NQU5	PAK6	Q16539	MAPK14	S351	T354P	354	Missense	distal	3	no	8.820	8.846	EPSD	COSMIC	5.915	Up-regulation
CMGC_MAPK_p38_MAPK14_ST	Q9NQU5	PAK6	Q16539	MAPK14	S351	S347F	347	Missense	distal	-4	no	8.820	9.524	EPSD	COSMIC	5.915	Up-regulation
CMGC_MAPK_p38_MAPK14_ST	Q9NQU5	PAK6	Q16539	MAPK14	S351	P348S	348	Missense	distal	-3	no	8.820	9.583	EPSD	COSMIC	5.915	Up-regulation
CMGC_MAPK_p38_MAPK14_ST	Q9NQU5	PAK6	Q16539	MAPK14	T354	T354P	354	Missense	central	0	yes	6.255	0.000	EPSD	COSMIC	5.915	Loss
CMGC_MAPK_p38_MAPK14_ST	Q9NQU5	PAK6	Q16539	MAPK14	T354	S347F	347	Missense	distal	-7	no	6.255	5.510	EPSD	COSMIC	5.915	Loss
CMGC_MAPK_p38_MAPK14_ST	Q9NQU5	PAK6	Q16539	MAPK14	T354	P348S	348	Missense	distal	-6	no	6.255	6.862	EPSD	COSMIC	5.915	Up-regulation
CMGC_MAPK_p38_MAPK14_ST	Q9NQU5	PAK6	Q16539	MAPK14	S616	L621Q	621	Missense	distal	5	no	10.103	10.391	EPSD	COSMIC	5.915	Up-regulation
CMGC_MAPK_p38_MAPK14_ST	P00533	EGFR	Q16539	MAPK14	S227	G221V	221	Missense	distal	-6	no	10.174	9.624	EPSD	COSMIC	5.915	Down-regulation
CMGC_MAPK_p38_MAPK14_ST	P00533	EGFR	Q16539	MAPK14	S227	R222H	222	Missense	distal	-5	no	10.174	10.717	EPSD	COSMIC	5.915	Up-regulation
CMGC_MAPK_p38_MAPK14_ST	P00533	EGFR	Q16539	MAPK14	S227	G221W	221	Missense	distal	-6	no	10.174	9.231	EPSD	COSMIC	5.915	Down-regulation
CMGC_MAPK_p38_MAPK14_ST	P00533	EGFR	Q16539	MAPK14	S227	S227Y	227	Missense	central	0	yes	10.174	0.000	EPSD	COSMIC	5.915	Loss
CMGC_MAPK_p38_MAPK14_ST	P00533	EGFR	Q16539	MAPK14	S227	G225C	225	Missense	proximal	-2	no	10.174	9.489	EPSD	COSMIC	5.915	Down-regulation
CMGC_MAPK_p38_MAPK14_ST	P00533	EGFR	Q16539	MAPK14	S227	S220F	220	Missense	distal	-7	no	10.174	9.428	EPSD	COSMIC	5.915	Down-regulation
CMGC_MAPK_p38_MAPK14_ST	P00533	EGFR	Q16539	MAPK14	S227	C231S	231	Missense	distal	4	no	10.174	11.325	EPSD	COSMIC	5.915	Up-regulation
CMGC_MAPK_p38_MAPK14_ST	P00533	EGFR	Q16539	MAPK14	S511	A508V	508	Missense	distal	-3	no	8.922	7.421	EPSD	COSMIC	5.915	Down-regulation
CMGC_MAPK_p38_MAPK14_ST	P00533	EGFR	Q16539	MAPK14	S511	L509F	509	Missense	proximal	-2	no	8.922	9.089	EPSD	COSMIC	5.915	Up-regulation
CMGC_MAPK_p38_MAPK14_ST	P00533	EGFR	Q16539	MAPK14	S511	S511Y	511	Missense	central	0	yes	8.922	0.000	EPSD	COSMIC	5.915	Loss
CMGC_MAPK_p38_MAPK14_ST	P00533	EGFR	Q16539	MAPK14	T693	A698V	698	Missense	distal	5	no	14.877	14.858	EPSD;PhosphoSitePlus	COSMIC	5.915	Down-regulation
CMGC_MAPK_p38_MAPK14_ST	P00533	EGFR	Q16539	MAPK14	T693	P691T	691	Missense	proximal	-2	no	14.877	14.157	EPSD;PhosphoSitePlus	COSMIC	5.915	Down-regulation
CMGC_MAPK_p38_MAPK14_ST	P00533	EGFR	Q16539	MAPK14	T693	L688P	688	Missense	distal	-5	no	14.877	14.596	EPSD;PhosphoSitePlus	COSMIC	5.915	Down-regulation
CMGC_MAPK_p38_MAPK14_ST	P00533	EGFR	Q16539	MAPK14	T693	P699S	699	Missense	distal	6	no	14.877	14.865	EPSD;PhosphoSitePlus	COSMIC	5.915	Down-regulation
CMGC_MAPK_p38_MAPK14_ST	P00533	EGFR	Q16539	MAPK14	T693	V689M	689	Missense	distal	-4	no	14.877	14.625	EPSD;PhosphoSitePlus	COSMIC	5.915	Down-regulation
CMGC_MAPK_p38_MAPK14_ST	P00533	EGFR	Q16539	MAPK14	T693	N700Y	700	Missense	distal	7	no	14.877	15.218	EPSD;PhosphoSitePlus	COSMIC	5.915	Up-regulation
CMGC_MAPK_p38_MAPK14_ST	P00533	EGFR	Q16539	MAPK14	T693	L692P	692	Missense	proximal	-1	no	14.877	14.691	EPSD;PhosphoSitePlus	COSMIC	5.915	Down-regulation
CMGC_MAPK_p38_MAPK14_ST	P00533	EGFR	Q16539	MAPK14	T693	P694S	694	Missense	proximal	1	no	14.877	7.593	EPSD;PhosphoSitePlus	COSMIC	5.915	Down-regulation
CMGC_MAPK_p38_MAPK14_ST	P00533	EGFR	Q16539	MAPK14	T693	N700S	700	Missense	distal	7	no	14.877	15.176	EPSD;PhosphoSitePlus	COSMIC	5.915	Up-regulation
CMGC_MAPK_p38_MAPK14_ST	P00533	EGFR	Q16539	MAPK14	T693	E690K	690	Missense	distal	-3	no	14.877	14.484	EPSD;PhosphoSitePlus	COSMIC	5.915	Down-regulation
CMGC_MAPK_p38_MAPK14_ST	P00533	EGFR	Q16539	MAPK14	T693	P691S	691	Missense	proximal	-2	no	14.877	14.388	EPSD;PhosphoSitePlus	COSMIC	5.915	Down-regulation
CMGC_MAPK_p38_MAPK14_ST	P00533	EGFR	Q16539	MAPK14	T693	V689L	689	Missense	distal	-4	no	14.877	15.154	EPSD;PhosphoSitePlus	COSMIC	5.915	Up-regulation
CMGC_MAPK_p38_MAPK14_ST	P00533	EGFR	Q16539	MAPK14	T693	E697D	697	Missense	distal	4	no	14.877	13.207	EPSD;PhosphoSitePlus	COSMIC	5.915	Down-regulation
CMGC_MAPK_p38_MAPK14_ST	P00533	EGFR	Q16539	MAPK14	T693	P694L	694	Missense	proximal	1	no	14.877	6.826	EPSD;PhosphoSitePlus	COSMIC	5.915	Down-regulation
CMGC_MAPK_p38_MAPK14_ST	P00533	EGFR	Q16539	MAPK14	T693	L688F	688	Missense	distal	-5	no	14.877	14.933	EPSD;PhosphoSitePlus	COSMIC	5.915	Up-regulation
CMGC_MAPK_p38_MAPK14_ST	P00533	EGFR	Q16539	MAPK14	T693	N700D	700	Missense	distal	7	no	14.877	15.198	EPSD;PhosphoSitePlus	COSMIC	5.915	Up-regulation
CMGC_MAPK_p38_MAPK14_ST	P00533	EGFR	Q16539	MAPK14	T693	S695G	695	Missense	proximal	2	no	14.877	14.648	EPSD;PhosphoSitePlus	COSMIC	5.915	Down-regulation
CMGC_MAPK_p38_MAPK14_ST	P00533	EGFR	Q16539	MAPK14	T693	R686S	686	Missense	distal	-7	no	14.877	15.045	EPSD;PhosphoSitePlus	COSMIC	5.915	Up-regulation
CMGC_MAPK_p38_MAPK14_ST	P00533	EGFR	Q16539	MAPK14	T693	T693A	693	Missense	central	0	yes	14.877	0.000	EPSD;PhosphoSitePlus	COSMIC	5.915	Loss
CMGC_MAPK_p38_MAPK14_ST	P00533	EGFR	Q16539	MAPK14	T693	E690V	690	Missense	distal	-3	no	14.877	13.747	EPSD;PhosphoSitePlus	COSMIC	5.915	Down-regulation
CMGC_MAPK_p38_MAPK14_ST	P00533	EGFR	Q16539	MAPK14	T693	L692F	692	Missense	proximal	-1	no	14.877	14.841	EPSD;PhosphoSitePlus	COSMIC	5.915	Down-regulation
CMGC_MAPK_p38_MAPK14_ST	P00533	EGFR	Q16539	MAPK14	T693	G696R	696	Missense	distal	3	no	14.877	14.863	EPSD;PhosphoSitePlus	COSMIC	5.915	Down-regulation
CMGC_MAPK_p38_MAPK14_ST	P00533	EGFR	Q16539	MAPK14	T693	G696E	696	Missense	distal	3	no	14.877	14.831	EPSD;PhosphoSitePlus	COSMIC	5.915	Down-regulation
CMGC_MAPK_p38_MAPK14_ST	P00533	EGFR	Q16539	MAPK14	S752	L747P	747	Missense	distal	-5	no	11.766	11.484	EPSD	COSMIC	5.915	Down-regulation
CMGC_MAPK_p38_MAPK14_ST	P00533	EGFR	Q16539	MAPK14	S752	L747F	747	Missense	distal	-5	no	11.766	11.821	EPSD	COSMIC	5.915	Up-regulation
CMGC_MAPK_p38_MAPK14_ST	P00533	EGFR	Q16539	MAPK14	S752	L747H	747	Missense	distal	-5	no	11.766	11.798	EPSD	COSMIC	5.915	Up-regulation
CMGC_MAPK_p38_MAPK14_ST	P00533	EGFR	Q16539	MAPK14	S752	L747S	747	Missense	distal	-5	no	11.766	11.036	EPSD	COSMIC	5.915	Down-regulation
CMGC_MAPK_p38_MAPK14_ST	P00533	EGFR	Q16539	MAPK14	S752	A750P	750	Missense	proximal	-2	no	11.766	12.428	EPSD	COSMIC	5.915	Up-regulation
CMGC_MAPK_p38_MAPK14_ST	P00533	EGFR	Q16539	MAPK14	S752	R748K	748	Missense	distal	-4	no	11.766	11.681	EPSD	COSMIC	5.915	Down-regulation
CMGC_MAPK_p38_MAPK14_ST	P00533	EGFR	Q16539	MAPK14	S752	I759V	759	Missense	distal	7	no	11.766	12.412	EPSD	COSMIC	5.915	Up-regulation
CMGC_MAPK_p38_MAPK14_ST	P00533	EGFR	Q16539	MAPK14	S752	K754Q	754	Missense	proximal	2	no	11.766	11.543	EPSD	COSMIC	5.915	Down-regulation
CMGC_MAPK_p38_MAPK14_ST	P00533	EGFR	Q16539	MAPK14	S752	T751A	751	Missense	proximal	-1	no	11.766	11.709	EPSD	COSMIC	5.915	Down-regulation
CMGC_MAPK_p38_MAPK14_ST	P00533	EGFR	Q16539	MAPK14	S752	E758G	758	Missense	distal	6	no	11.766	11.807	EPSD	COSMIC	5.915	Up-regulation
CMGC_MAPK_p38_MAPK14_ST	P00533	EGFR	Q16539	MAPK14	S752	K757N	757	Missense	distal	5	no	11.766	12.035	EPSD	COSMIC	5.915	Up-regulation
CMGC_MAPK_p38_MAPK14_ST	P00533	EGFR	Q16539	MAPK14	S752	S752Y	752	Missense	central	0	yes	11.766	0.000	EPSD	COSMIC	5.915	Loss
CMGC_MAPK_p38_MAPK14_ST	P00533	EGFR	Q16539	MAPK14	S752	T751I	751	Missense	proximal	-1	no	11.766	11.627	EPSD	COSMIC;GDSC;CCLE	5.915	Down-regulation
CMGC_MAPK_p38_MAPK14_ST	P00533	EGFR	Q16539	MAPK14	S752	E746V	746	Missense	distal	-6	no	11.766	10.906	EPSD	COSMIC	5.915	Down-regulation
CMGC_MAPK_p38_MAPK14_ST	P00533	EGFR	Q16539	MAPK14	S752	A750T	750	Missense	proximal	-2	no	11.766	11.708	EPSD	COSMIC	5.915	Down-regulation
CMGC_MAPK_p38_MAPK14_ST	P00533	EGFR	Q16539	MAPK14	S752	S752F	752	Missense	central	0	yes	11.766	0.000	EPSD	COSMIC	5.915	Loss
CMGC_MAPK_p38_MAPK14_ST	P00533	EGFR	Q16539	MAPK14	S752	E746A	746	Missense	distal	-6	no	11.766	11.394	EPSD	COSMIC;GDSC	5.915	Down-regulation
CMGC_MAPK_p38_MAPK14_ST	P00533	EGFR	Q16539	MAPK14	S752	A755D	755	Missense	distal	3	no	11.766	11.802	EPSD	COSMIC;CCLE	5.915	Up-regulation
CMGC_MAPK_p38_MAPK14_ST	P00533	EGFR	Q16539	MAPK14	S752	K754R	754	Missense	proximal	2	no	11.766	11.969	EPSD	COSMIC	5.915	Up-regulation
CMGC_MAPK_p38_MAPK14_ST	P00533	EGFR	Q16539	MAPK14	S752	E749K	749	Missense	distal	-3	no	11.766	11.373	EPSD	COSMIC	5.915	Down-regulation
CMGC_MAPK_p38_MAPK14_ST	P00533	EGFR	Q16539	MAPK14	S752	T751L	751	Missense	proximal	-1	no	11.766	11.927	EPSD	COSMIC	5.915	Up-regulation
CMGC_MAPK_p38_MAPK14_ST	P00533	EGFR	Q16539	MAPK14	S752	E758K	758	Missense	distal	6	no	11.766	11.760	EPSD	COSMIC	5.915	Down-regulation
CMGC_MAPK_p38_MAPK14_ST	P00533	EGFR	Q16539	MAPK14	S752	K745R	745	Missense	distal	-7	no	11.766	11.500	EPSD	COSMIC	5.915	Down-regulation
CMGC_MAPK_p38_MAPK14_ST	P00533	EGFR	Q16539	MAPK14	S752	E746I	746	Missense	distal	-6	no	11.766	10.641	EPSD	COSMIC	5.915	Down-regulation
CMGC_MAPK_p38_MAPK14_ST	P00533	EGFR	Q16539	MAPK14	S752	A755T	755	Missense	distal	3	no	11.766	11.765	EPSD	COSMIC	5.915	Down-regulation
CMGC_MAPK_p38_MAPK14_ST	P00533	EGFR	Q16539	MAPK14	S752	K754A	754	Missense	proximal	2	no	11.766	11.851	EPSD	COSMIC	5.915	Up-regulation
CMGC_MAPK_p38_MAPK14_ST	P00533	EGFR	Q16539	MAPK14	S752	N756S	756	Missense	distal	4	no	11.766	12.282	EPSD	COSMIC	5.915	Up-regulation
CMGC_MAPK_p38_MAPK14_ST	P00533	EGFR	Q16539	MAPK14	S752	N756Y	756	Missense	distal	4	no	11.766	11.235	EPSD	COSMIC	5.915	Down-regulation
CMGC_MAPK_p38_MAPK14_ST	P00533	EGFR	Q16539	MAPK14	S752	K757R	757	Missense	distal	5	no	11.766	12.060	EPSD	COSMIC	5.915	Up-regulation
CMGC_MAPK_p38_MAPK14_ST	P00533	EGFR	Q16539	MAPK14	S752	A755G	755	Missense	distal	3	no	11.766	11.793	EPSD	COSMIC	5.915	Up-regulation
CMGC_MAPK_p38_MAPK14_ST	P00533	EGFR	Q16539	MAPK14	S752	E746G	746	Missense	distal	-6	no	11.766	11.455	EPSD	COSMIC	5.915	Down-regulation
CMGC_MAPK_p38_MAPK14_ST	P00533	EGFR	Q16539	MAPK14	S752	E749V	749	Missense	distal	-3	no	11.766	10.636	EPSD	COSMIC	5.915	Down-regulation
CMGC_MAPK_p38_MAPK14_ST	P00533	EGFR	Q16539	MAPK14	S752	E749G	749	Missense	distal	-3	no	11.766	11.611	EPSD	COSMIC	5.915	Down-regulation
CMGC_MAPK_p38_MAPK14_ST	P00533	EGFR	Q16539	MAPK14	S752	S752P	752	Missense	central	0	yes	11.766	0.000	EPSD	COSMIC	5.915	Loss
CMGC_MAPK_p38_MAPK14_ST	P00533	EGFR	Q16539	MAPK14	S752	E758D	758	Missense	distal	6	no	11.766	11.665	EPSD	COSMIC	5.915	Down-regulation
CMGC_MAPK_p38_MAPK14_ST	P00533	EGFR	Q16539	MAPK14	S752	K745T	745	Missense	distal	-7	no	11.766	11.599	EPSD	COSMIC	5.915	Down-regulation
CMGC_MAPK_p38_MAPK14_ST	P00533	EGFR	Q16539	MAPK14	S752	E746K	746	Missense	distal	-6	no	11.766	11.351	EPSD	COSMIC;GDSC	5.915	Down-regulation
CMGC_MAPK_p38_MAPK14_ST	P00533	EGFR	Q16539	MAPK14	S752	A755V	755	Missense	distal	3	no	11.766	11.793	EPSD	COSMIC	5.915	Up-regulation
CMGC_MAPK_p38_MAPK14_ST	P00533	EGFR	Q16539	MAPK14	S752	L747V	747	Missense	distal	-5	no	11.766	11.640	EPSD	COSMIC	5.915	Down-regulation
CMGC_MAPK_p38_MAPK14_ST	P00533	EGFR	Q16539	MAPK14	S752	T751P	751	Missense	proximal	-1	no	11.766	11.742	EPSD	COSMIC	5.915	Down-regulation
CMGC_MAPK_p38_MAPK14_ST	P00533	EGFR	Q16539	MAPK14	S752	R748I	748	Missense	distal	-4	no	11.766	11.922	EPSD	COSMIC	5.915	Up-regulation
CMGC_MAPK_p38_MAPK14_ST	P00533	EGFR	Q16539	MAPK14	S752	K757M	757	Missense	distal	5	no	11.766	11.891	EPSD	COSMIC	5.915	Up-regulation
CMGC_MAPK_p38_MAPK14_ST	P00533	EGFR	Q16539	MAPK14	S752	P753F	753	Missense	proximal	1	no	11.766	5.762	EPSD	COSMIC	5.915	Loss
CMGC_MAPK_p38_MAPK14_ST	P00533	EGFR	Q16539	MAPK14	S925	S924P	924	Missense	proximal	-1	no	6.152	6.244	EPSD	COSMIC	5.915	Up-regulation
CMGC_MAPK_p38_MAPK14_ST	P00533	EGFR	Q16539	MAPK14	S925	R932S	932	Missense	distal	7	no	6.152	6.117	EPSD	COSMIC	5.915	Down-regulation
CMGC_MAPK_p38_MAPK14_ST	P00533	EGFR	Q16539	MAPK14	S925	S925F	925	Missense	central	0	yes	6.152	0.000	EPSD	COSMIC	5.915	Loss
CMGC_MAPK_p38_MAPK14_ST	P00533	EGFR	Q16539	MAPK14	S925	R932C	932	Missense	distal	7	no	6.152	5.552	EPSD	COSMIC	5.915	Loss
CMGC_MAPK_p38_MAPK14_ST	P00533	EGFR	Q16539	MAPK14	S925	G930E	930	Missense	distal	5	no	6.152	6.369	EPSD	COSMIC	5.915	Up-regulation
CMGC_MAPK_p38_MAPK14_ST	P00533	EGFR	Q16539	MAPK14	S925	P919L	919	Missense	distal	-6	no	6.152	5.539	EPSD	COSMIC	5.915	Loss
CMGC_MAPK_p38_MAPK14_ST	P00533	EGFR	Q16539	MAPK14	S991	F997L	997	Missense	distal	6	no	10.756	10.986	EPSD	COSMIC	5.915	Up-regulation
CMGC_MAPK_p38_MAPK14_ST	P00533	EGFR	Q16539	MAPK14	S991	D984N	984	Missense	distal	-7	no	10.756	10.976	EPSD	COSMIC	5.915	Up-regulation
CMGC_MAPK_p38_MAPK14_ST	P00533	EGFR	Q16539	MAPK14	S991	M987R	987	Missense	distal	-4	no	10.756	10.696	EPSD	COSMIC	5.915	Down-regulation
CMGC_MAPK_p38_MAPK14_ST	P00533	EGFR	Q16539	MAPK14	T993	F997L	997	Missense	distal	4	no	5.643	6.139	EPSD	COSMIC	5.915	Gain
CMGC_MAPK_p38_MAPK14_ST	P00533	EGFR	Q16539	MAPK14	T993	M987R	987	Missense	distal	-6	no	5.643	6.397	EPSD	COSMIC	5.915	Gain
CMGC_MAPK_p38_MAPK14_ST	P00533	EGFR	Q16539	MAPK14	S1026	S1025T	1025	Missense	proximal	-1	no	10.355	10.471	EPSD	COSMIC	5.915	Up-regulation
CMGC_MAPK_p38_MAPK14_ST	P00533	EGFR	Q16539	MAPK14	S1026	P1027S	1027	Missense	proximal	1	no	10.355	3.071	EPSD	COSMIC	5.915	Loss
CMGC_MAPK_p38_MAPK14_ST	P00533	EGFR	Q16539	MAPK14	S1026	P1019S	1019	Missense	distal	-7	no	10.355	10.442	EPSD	COSMIC	5.915	Up-regulation
CMGC_MAPK_p38_MAPK14_ST	P00533	EGFR	Q16539	MAPK14	S1026	G1022S	1022	Missense	distal	-4	no	10.355	10.357	EPSD	COSMIC	5.915	Up-regulation
CMGC_MAPK_p38_MAPK14_ST	P00533	EGFR	Q16539	MAPK14	S1026	S1028L	1028	Missense	proximal	2	no	10.355	9.866	EPSD	COSMIC	5.915	Down-regulation
CMGC_MAPK_p38_MAPK14_ST	P00533	EGFR	Q16539	MAPK14	S1026	Q1020H	1020	Missense	distal	-6	no	10.355	10.062	EPSD	COSMIC	5.915	Down-regulation
CMGC_MAPK_p38_MAPK14_ST	P00533	EGFR	Q16539	MAPK14	S1028	S1025T	1025	Missense	distal	-3	no	8.189	7.872	EPSD	COSMIC	5.915	Down-regulation
CMGC_MAPK_p38_MAPK14_ST	P00533	EGFR	Q16539	MAPK14	S1028	P1027S	1027	Missense	proximal	-1	no	8.189	8.097	EPSD	COSMIC	5.915	Down-regulation
CMGC_MAPK_p38_MAPK14_ST	P00533	EGFR	Q16539	MAPK14	S1028	G1022S	1022	Missense	distal	-6	no	8.189	8.670	EPSD	COSMIC	5.915	Up-regulation
CMGC_MAPK_p38_MAPK14_ST	P00533	EGFR	Q16539	MAPK14	S1028	S1028L	1028	Missense	central	0	yes	8.189	0.000	EPSD	COSMIC	5.915	Loss
CMGC_MAPK_p38_MAPK14_ST	P00533	EGFR	Q16539	MAPK14	S1028	L1034I	1034	Missense	distal	6	no	8.189	8.106	EPSD	COSMIC	5.915	Down-regulation
CMGC_MAPK_p38_MAPK14_ST	P00533	EGFR	Q16539	MAPK14	T1032	S1025T	1025	Missense	distal	-7	no	11.989	11.919	EPSD	COSMIC	5.915	Down-regulation
CMGC_MAPK_p38_MAPK14_ST	P00533	EGFR	Q16539	MAPK14	T1032	P1027S	1027	Missense	distal	-5	no	11.989	11.541	EPSD	COSMIC	5.915	Down-regulation
CMGC_MAPK_p38_MAPK14_ST	P00533	EGFR	Q16539	MAPK14	T1032	S1036R	1036	Missense	distal	4	no	11.989	11.272	EPSD	COSMIC	5.915	Down-regulation
CMGC_MAPK_p38_MAPK14_ST	P00533	EGFR	Q16539	MAPK14	T1032	S1028L	1028	Missense	distal	-4	no	11.989	12.589	EPSD	COSMIC	5.915	Up-regulation
CMGC_MAPK_p38_MAPK14_ST	P00533	EGFR	Q16539	MAPK14	T1032	L1034I	1034	Missense	proximal	2	no	11.989	11.999	EPSD	COSMIC	5.915	Up-regulation
CMGC_MAPK_p38_MAPK14_ST	P00533	EGFR	Q16539	MAPK14	S1039	T1041A	1041	Missense	proximal	2	no	8.978	8.949	PhosphoSitePlus;EPSD	COSMIC	5.915	Down-regulation
CMGC_MAPK_p38_MAPK14_ST	P00533	EGFR	Q16539	MAPK14	S1039	S1036R	1036	Missense	distal	-3	no	8.978	9.490	PhosphoSitePlus;EPSD	COSMIC	5.915	Up-regulation
CMGC_MAPK_p38_MAPK14_ST	P00533	EGFR	Q16539	MAPK14	S1039	L1034I	1034	Missense	distal	-5	no	8.978	8.648	PhosphoSitePlus;EPSD	COSMIC	5.915	Down-regulation
CMGC_MAPK_p38_MAPK14_ST	P00533	EGFR	Q16539	MAPK14	S1039	S1045F	1045	Missense	distal	6	no	8.978	8.621	PhosphoSitePlus;EPSD	COSMIC	5.915	Down-regulation
CMGC_MAPK_p38_MAPK14_ST	P00533	EGFR	Q16539	MAPK14	S1039	T1046I	1046	Missense	distal	7	no	8.978	8.566	PhosphoSitePlus;EPSD	COSMIC	5.915	Down-regulation
CMGC_MAPK_p38_MAPK14_ST	P00533	EGFR	Q16539	MAPK14	S1064	C1058Y	1058	Missense	distal	-6	no	5.709	6.236	EPSD	COSMIC	5.915	Gain
CMGC_MAPK_p38_MAPK14_ST	P00533	EGFR	Q16539	MAPK14	S1064	P1059L	1059	Missense	distal	-5	no	5.709	5.990	EPSD	COSMIC	5.915	Gain
CMGC_MAPK_p38_MAPK14_ST	P00533	EGFR	Q16539	MAPK14	S1130	H1124Q	1124	Missense	distal	-6	no	6.415	6.708	EPSD	COSMIC;CCLE	5.915	Up-regulation
CMGC_MAPK_p38_MAPK14_ST	P00533	EGFR	Q16539	MAPK14	S1130	E1137K	1137	Missense	distal	7	no	6.415	5.708	EPSD	COSMIC	5.915	Loss
CMGC_MAPK_p38_MAPK14_ST	P00533	EGFR	Q16539	MAPK14	S1130	S1130G	1130	Missense	central	0	yes	6.415	0.000	EPSD	COSMIC;GDSC;CCLE	5.915	Loss
CMGC_MAPK_p38_MAPK14_ST	P00533	EGFR	Q16539	MAPK14	S1130	H1129Y	1129	Missense	proximal	-1	no	6.415	6.368	EPSD	COSMIC	5.915	Down-regulation
CMGC_MAPK_p38_MAPK14_ST	P00533	EGFR	Q16539	MAPK14	S1130	P1136L	1136	Missense	distal	6	no	6.415	6.276	EPSD	COSMIC	5.915	Down-regulation
CMGC_MAPK_p38_MAPK14_ST	P00533	EGFR	Q16539	MAPK14	S1130	S1130R	1130	Missense	central	0	yes	6.415	0.000	EPSD	COSMIC	5.915	Loss
CMGC_MAPK_p38_MAPK14_ST	P00533	EGFR	Q16539	MAPK14	S1130	P1136A	1136	Missense	distal	6	no	6.415	6.458	EPSD	COSMIC	5.915	Up-regulation
CMGC_MAPK_p38_MAPK14_ST	P00533	EGFR	Q16539	MAPK14	S1130	D1127N	1127	Missense	distal	-3	no	6.415	6.256	EPSD	COSMIC;GDSC;CCLE	5.915	Down-regulation
CMGC_MAPK_p38_MAPK14_ST	P00533	EGFR	Q16539	MAPK14	S1153	A1155D	1155	Missense	proximal	2	no	7.391	7.169	EPSD	COSMIC	5.915	Down-regulation
CMGC_MAPK_p38_MAPK14_ST	P00533	EGFR	Q16539	MAPK14	S1153	V1147I	1147	Missense	distal	-6	no	7.391	7.127	EPSD	COSMIC	5.915	Down-regulation
CMGC_MAPK_p38_MAPK14_ST	P00533	EGFR	Q16539	MAPK14	S1153	Q1159H	1159	Missense	distal	6	no	7.391	7.272	EPSD	COSMIC;GDSC;CCLE	5.915	Down-regulation
CMGC_MAPK_p38_MAPK14_ST	P00533	EGFR	Q16539	MAPK14	S1153	A1158P	1158	Missense	distal	5	no	7.391	7.579	EPSD	COSMIC	5.915	Up-regulation
CMGC_MAPK_p38_MAPK14_ST	P00533	EGFR	Q16539	MAPK14	S1153	D1152H	1152	Missense	proximal	-1	no	7.391	7.182	EPSD	COSMIC	5.915	Down-regulation
CMGC_MAPK_p38_MAPK14_ST	Q06413	MEF2C	Q16539	MAPK14	S82	V85A	85	Missense	distal	3	no	7.468	7.440	EPSD	COSMIC	5.915	Down-regulation
CMGC_MAPK_p38_MAPK14_ST	Q06413	MEF2C	Q16539	MAPK14	S82	P75L	75	Missense	distal	-7	no	7.468	7.275	EPSD	COSMIC	5.915	Down-regulation
CMGC_MAPK_p38_MAPK14_ST	Q06413	MEF2C	Q16539	MAPK14	S82	S78T	78	Missense	distal	-4	no	7.468	7.745	EPSD	COSMIC	5.915	Up-regulation
CMGC_MAPK_p38_MAPK14_ST	Q06413	MEF2C	Q16539	MAPK14	S82	R79W	79	Missense	distal	-3	no	7.468	5.111	EPSD	COSMIC	5.915	Loss
CMGC_MAPK_p38_MAPK14_ST	Q06413	MEF2C	Q16539	MAPK14	S82	E77K	77	Missense	distal	-5	no	7.468	7.802	EPSD	COSMIC	5.915	Up-regulation
CMGC_MAPK_p38_MAPK14_ST	Q06413	MEF2C	Q16539	MAPK14	S98	K91E	91	Missense	distal	-7	no	10.232	10.286	EPSD	COSMIC	5.915	Up-regulation
CMGC_MAPK_p38_MAPK14_ST	Q06413	MEF2C	Q16539	MAPK14	S98	C96S	96	Missense	proximal	-2	no	10.232	11.367	EPSD	COSMIC;GDSC;CCLE	5.915	Up-regulation
CMGC_MAPK_p38_MAPK14_ST	Q06413	MEF2C	Q16539	MAPK14	S98	D100N	100	Missense	proximal	2	no	10.232	10.462	EPSD	COSMIC	5.915	Up-regulation
CMGC_MAPK_p38_MAPK14_ST	Q06413	MEF2C	Q16539	MAPK14	S98	G95C	95	Missense	distal	-3	no	10.232	9.487	EPSD	COSMIC	5.915	Down-regulation
CMGC_MAPK_p38_MAPK14_ST	Q06413	MEF2C	Q16539	MAPK14	S98	K91N	91	Missense	distal	-7	no	10.232	9.924	EPSD	COSMIC	5.915	Down-regulation
CMGC_MAPK_p38_MAPK14_ST	Q06413	MEF2C	Q16539	MAPK14	S98	A103S	103	Missense	distal	5	no	10.232	10.871	EPSD	COSMIC	5.915	Up-regulation
CMGC_MAPK_p38_MAPK14_ST	Q06413	MEF2C	Q16539	MAPK14	S98	K91R	91	Missense	distal	-7	no	10.232	9.967	EPSD	COSMIC	5.915	Down-regulation
CMGC_MAPK_p38_MAPK14_ST	Q06413	MEF2C	Q16539	MAPK14	S110	V107I	107	Missense	distal	-3	no	11.217	11.058	EPSD	COSMIC	5.915	Down-regulation
CMGC_MAPK_p38_MAPK14_ST	Q06413	MEF2C	Q16539	MAPK14	S110	S110C	110	Missense	central	0	yes	11.217	0.000	EPSD	COSMIC	5.915	Loss
CMGC_MAPK_p38_MAPK14_ST	Q06413	MEF2C	Q16539	MAPK14	S110	S110R	110	Missense	central	0	yes	11.217	0.000	EPSD	COSMIC	5.915	Loss
CMGC_MAPK_p38_MAPK14_ST	Q06413	MEF2C	Q16539	MAPK14	S110	A103S	103	Missense	distal	-7	no	11.217	11.103	EPSD	COSMIC	5.915	Down-regulation
CMGC_MAPK_p38_MAPK14_ST	Q06413	MEF2C	Q16539	MAPK14	S110	S106R	106	Missense	distal	-4	no	11.217	11.227	EPSD	COSMIC	5.915	Up-regulation
CMGC_MAPK_p38_MAPK14_ST	Q06413	MEF2C	Q16539	MAPK14	S110	S106N	106	Missense	distal	-4	no	11.217	11.290	EPSD	COSMIC	5.915	Up-regulation
CMGC_MAPK_p38_MAPK14_ST	Q06413	MEF2C	Q16539	MAPK14	S110	S106T	106	Missense	distal	-4	no	11.217	11.494	EPSD	COSMIC	5.915	Up-regulation
CMGC_MAPK_p38_MAPK14_ST	Q06413	MEF2C	Q16539	MAPK14	S110	S106G	106	Missense	distal	-4	no	11.217	11.214	EPSD	COSMIC	5.915	Down-regulation
CMGC_MAPK_p38_MAPK14_ST	Q06413	MEF2C	Q16539	MAPK14	S176	L177P	177	Missense	proximal	1	no	2.475	10.526	EPSD	COSMIC	5.915	Gain
CMGC_MAPK_p38_MAPK14_ST	Q06413	MEF2C	Q16539	MAPK14	S183	S181F	181	Missense	proximal	-2	no	8.120	7.396	EPSD	COSMIC	5.915	Down-regulation
CMGC_MAPK_p38_MAPK14_ST	Q06413	MEF2C	Q16539	MAPK14	S183	L177P	177	Missense	distal	-6	no	8.120	8.733	EPSD	COSMIC	5.915	Up-regulation
CMGC_MAPK_p38_MAPK14_ST	Q06413	MEF2C	Q16539	MAPK14	S183	N180I	180	Missense	distal	-3	no	8.120	7.195	EPSD	COSMIC	5.915	Down-regulation
CMGC_MAPK_p38_MAPK14_ST	Q06413	MEF2C	Q16539	MAPK14	S183	G185D	185	Missense	proximal	2	no	8.120	7.863	EPSD	COSMIC	5.915	Down-regulation
CMGC_MAPK_p38_MAPK14_ST	Q06413	MEF2C	Q16539	MAPK14	S183	S176R	176	Missense	distal	-7	no	8.120	7.951	EPSD	COSMIC	5.915	Down-regulation
CMGC_MAPK_p38_MAPK14_ST	Q06413	MEF2C	Q16539	MAPK14	S183	M182I	182	Missense	proximal	-1	no	8.120	7.974	EPSD	COSMIC	5.915	Down-regulation
CMGC_MAPK_p38_MAPK14_ST	Q06413	MEF2C	Q16539	MAPK14	S222	G215R	215	Missense	distal	-7	no	11.367	11.266	EPSD	COSMIC	5.915	Down-regulation
CMGC_MAPK_p38_MAPK14_ST	Q06413	MEF2C	Q16539	MAPK14	S222	S222P	222	Missense	central	0	yes	11.367	0.000	EPSD	COSMIC	5.915	Loss
CMGC_MAPK_p38_MAPK14_ST	Q06413	MEF2C	Q16539	MAPK14	S222	N221H	221	Missense	proximal	-1	no	11.367	11.344	EPSD	COSMIC	5.915	Down-regulation
CMGC_MAPK_p38_MAPK14_ST	Q06413	MEF2C	Q16539	MAPK14	S222	G215E	215	Missense	distal	-7	no	11.367	11.585	EPSD	COSMIC	5.915	Up-regulation
CMGC_MAPK_p38_MAPK14_ST	Q06413	MEF2C	Q16539	MAPK14	S222	N218H	218	Missense	distal	-4	no	11.367	11.516	EPSD	COSMIC	5.915	Up-regulation
CMGC_MAPK_p38_MAPK14_ST	Q06413	MEF2C	Q16539	MAPK14	S228	S222P	222	Missense	distal	-6	no	9.897	9.291	EPSD	COSMIC	5.915	Down-regulation
CMGC_MAPK_p38_MAPK14_ST	Q06413	MEF2C	Q16539	MAPK14	S228	N221H	221	Missense	distal	-7	no	9.897	9.645	EPSD	COSMIC	5.915	Down-regulation
CMGC_MAPK_p38_MAPK14_ST	Q06413	MEF2C	Q16539	MAPK14	S240	S240P	240	Missense	central	0	yes	10.836	0.000	EPSD	COSMIC	5.915	Loss
CMGC_MAPK_p38_MAPK14_ST	Q06413	MEF2C	Q16539	MAPK14	T293	S287F	287	Missense	distal	-6	no	11.739	9.974	EPSD;PhosphoSitePlus	COSMIC	5.915	Down-regulation
CMGC_MAPK_p38_MAPK14_ST	Q06413	MEF2C	Q16539	MAPK14	T293	V298I	298	Missense	distal	5	no	11.739	11.303	EPSD;PhosphoSitePlus	COSMIC	5.915	Down-regulation
CMGC_MAPK_p38_MAPK14_ST	Q06413	MEF2C	Q16539	MAPK14	T293	P294Q	294	Missense	proximal	1	no	11.739	4.530	EPSD;PhosphoSitePlus	COSMIC	5.915	Loss
CMGC_MAPK_p38_MAPK14_ST	Q06413	MEF2C	Q16539	MAPK14	T293	V296I	296	Missense	distal	3	no	11.739	11.792	EPSD;PhosphoSitePlus	COSMIC	5.915	Up-regulation
CMGC_MAPK_p38_MAPK14_ST	Q06413	MEF2C	Q16539	MAPK14	T300	Q306K	306	Missense	distal	6	no	9.337	9.400	EPSD;PhosphoSitePlus	COSMIC	5.915	Up-regulation
CMGC_MAPK_p38_MAPK14_ST	Q06413	MEF2C	Q16539	MAPK14	T300	V298I	298	Missense	proximal	-2	no	9.337	9.596	EPSD;PhosphoSitePlus	COSMIC	5.915	Up-regulation
CMGC_MAPK_p38_MAPK14_ST	Q06413	MEF2C	Q16539	MAPK14	T300	P294Q	294	Missense	distal	-6	no	9.337	9.168	EPSD;PhosphoSitePlus	COSMIC	5.915	Down-regulation
CMGC_MAPK_p38_MAPK14_ST	Q06413	MEF2C	Q16539	MAPK14	T300	V296I	296	Missense	distal	-4	no	9.337	9.182	EPSD;PhosphoSitePlus	COSMIC	5.915	Down-regulation
CMGC_MAPK_p38_MAPK14_ST	Q06413	MEF2C	Q16539	MAPK14	T300	P304Q	304	Missense	distal	4	no	9.337	8.855	EPSD;PhosphoSitePlus	COSMIC	5.915	Down-regulation
CMGC_MAPK_p38_MAPK14_ST	Q06413	MEF2C	Q16539	MAPK14	S387	S387P	387	Missense	central	0	yes	5.932	0.000	PhosphoSitePlus;EPSD	COSMIC	5.915	Loss
CMGC_MAPK_p38_MAPK14_ST	Q06413	MEF2C	Q16539	MAPK14	S387	N389S	389	Missense	proximal	2	no	5.932	6.188	PhosphoSitePlus;EPSD	COSMIC;GDSC	5.915	Up-regulation
CMGC_MAPK_p38_MAPK14_ST	Q06413	MEF2C	Q16539	MAPK14	S387	S384C	384	Missense	distal	-3	no	5.932	4.248	PhosphoSitePlus;EPSD	COSMIC	5.915	Loss
CMGC_MAPK_p38_MAPK14_ST	Q06413	MEF2C	Q16539	MAPK14	S387	L388F	388	Missense	proximal	1	no	5.932	7.979	PhosphoSitePlus;EPSD	COSMIC	5.915	Up-regulation
CMGC_MAPK_p38_MAPK14_ST	Q06413	MEF2C	Q16539	MAPK14	S387	L380I	380	Missense	distal	-7	no	5.932	5.791	PhosphoSitePlus;EPSD	COSMIC	5.915	Loss
CMGC_MAPK_p38_MAPK14_ST	Q06413	MEF2C	Q16539	MAPK14	S387	S381G	381	Missense	distal	-6	no	5.932	5.451	PhosphoSitePlus;EPSD	COSMIC	5.915	Loss
CMGC_MAPK_p38_MAPK14_ST	Q06413	MEF2C	Q16539	MAPK14	S387	I390M	390	Missense	distal	3	no	5.932	5.873	PhosphoSitePlus;EPSD	COSMIC	5.915	Loss
CMGC_MAPK_p38_MAPK14_ST	Q06413	MEF2C	Q16539	MAPK14	S387	P394R	394	Missense	distal	7	no	5.932	6.188	PhosphoSitePlus;EPSD	COSMIC	5.915	Up-regulation
CMGC_MAPK_p38_MAPK14_ST	Q06413	MEF2C	Q16539	MAPK14	S387	P394T	394	Missense	distal	7	no	5.932	5.833	PhosphoSitePlus;EPSD	COSMIC	5.915	Loss
CMGC_MAPK_p38_MAPK14_ST	Q06413	MEF2C	Q16539	MAPK14	S396	S396L	396	Missense	central	0	yes	11.143	0.000	EPSD	COSMIC	5.915	Loss
CMGC_MAPK_p38_MAPK14_ST	Q06413	MEF2C	Q16539	MAPK14	S396	T402M	402	Missense	distal	6	no	11.143	11.154	EPSD	COSMIC	5.915	Up-regulation
CMGC_MAPK_p38_MAPK14_ST	Q06413	MEF2C	Q16539	MAPK14	S396	D400Y	400	Missense	distal	4	no	11.143	11.265	EPSD	COSMIC	5.915	Up-regulation
CMGC_MAPK_p38_MAPK14_ST	Q06413	MEF2C	Q16539	MAPK14	S396	N389S	389	Missense	distal	-7	no	11.143	11.353	EPSD	COSMIC;GDSC	5.915	Up-regulation
CMGC_MAPK_p38_MAPK14_ST	Q06413	MEF2C	Q16539	MAPK14	S396	I390M	390	Missense	distal	-6	no	11.143	11.577	EPSD	COSMIC	5.915	Up-regulation
CMGC_MAPK_p38_MAPK14_ST	Q06413	MEF2C	Q16539	MAPK14	S396	R401T	401	Missense	distal	5	no	11.143	11.286	EPSD	COSMIC	5.915	Up-regulation
CMGC_MAPK_p38_MAPK14_ST	Q06413	MEF2C	Q16539	MAPK14	S396	R401K	401	Missense	distal	5	no	11.143	10.848	EPSD	COSMIC	5.915	Down-regulation
CMGC_MAPK_p38_MAPK14_ST	Q06413	MEF2C	Q16539	MAPK14	S396	P394R	394	Missense	proximal	-2	no	11.143	10.454	EPSD	COSMIC	5.915	Down-regulation
CMGC_MAPK_p38_MAPK14_ST	Q06413	MEF2C	Q16539	MAPK14	S396	P394T	394	Missense	proximal	-2	no	11.143	10.423	EPSD	COSMIC	5.915	Down-regulation
CMGC_MAPK_p38_MAPK14_ST	Q06413	MEF2C	Q16539	MAPK14	T402	D400Y	400	Missense	proximal	-2	no	5.093	6.296	EPSD	COSMIC	5.915	Gain
CMGC_MAPK_p38_MAPK14_ST	Q06413	MEF2C	Q16539	MAPK14	T404	T402M	402	Missense	proximal	-2	no	8.260	8.168	EPSD	COSMIC	5.915	Down-regulation
CMGC_MAPK_p38_MAPK14_ST	Q06413	MEF2C	Q16539	MAPK14	T404	D400Y	400	Missense	distal	-4	no	8.260	7.763	EPSD	COSMIC	5.915	Down-regulation
CMGC_MAPK_p38_MAPK14_ST	Q06413	MEF2C	Q16539	MAPK14	T404	P405R	405	Missense	proximal	1	no	8.260	0.325	EPSD	COSMIC	5.915	Loss
CMGC_MAPK_p38_MAPK14_ST	Q06413	MEF2C	Q16539	MAPK14	T404	P405T	405	Missense	proximal	1	no	8.260	0.807	EPSD	COSMIC	5.915	Loss
CMGC_MAPK_p38_MAPK14_ST	Q06413	MEF2C	Q16539	MAPK14	T404	S406L	406	Missense	proximal	2	no	8.260	7.771	EPSD	COSMIC	5.915	Down-regulation
CMGC_MAPK_p38_MAPK14_ST	Q06413	MEF2C	Q16539	MAPK14	T404	R401T	401	Missense	distal	-3	no	8.260	7.430	EPSD	COSMIC	5.915	Down-regulation
CMGC_MAPK_p38_MAPK14_ST	Q06413	MEF2C	Q16539	MAPK14	T404	R401K	401	Missense	distal	-3	no	8.260	6.572	EPSD	COSMIC	5.915	Down-regulation
CMGC_MAPK_p38_MAPK14_ST	Q06413	MEF2C	Q16539	MAPK14	T404	R407G	407	Missense	distal	3	no	8.260	8.274	EPSD	COSMIC	5.915	Up-regulation
CMGC_MAPK_p38_MAPK14_ST	Q06413	MEF2C	Q16539	MAPK14	S419	D422Y	422	Missense	distal	3	no	14.517	14.507	EPSD	COSMIC	5.915	Down-regulation
CMGC_MAPK_p38_MAPK14_ST	Q06413	MEF2C	Q16539	MAPK14	S419	P420H	420	Missense	proximal	1	no	14.517	0.863	EPSD	COSMIC	5.915	Loss
CMGC_MAPK_p38_MAPK14_ST	Q06413	MEF2C	Q16539	MAPK14	S419	E415K	415	Missense	distal	-4	no	14.517	14.742	EPSD	COSMIC	5.915	Up-regulation
CMGC_MAPK_p38_MAPK14_ST	Q06413	MEF2C	Q16539	MAPK14	S419	T412M	412	Missense	distal	-7	no	14.517	14.571	EPSD	COSMIC	5.915	Up-regulation
CMGC_MAPK_p38_MAPK14_ST	Q06413	MEF2C	Q16539	MAPK14	S419	A416V	416	Missense	distal	-3	no	14.517	13.016	EPSD	COSMIC	5.915	Down-regulation
CMGC_MAPK_p38_MAPK14_ST	Q06413	MEF2C	Q16539	MAPK14	S419	S419P	419	Missense	central	0	yes	14.517	0.000	EPSD	COSMIC	5.915	Loss
CMGC_MAPK_p38_MAPK14_ST	Q06413	MEF2C	Q16539	MAPK14	S419	R413C	413	Missense	distal	-6	no	14.517	13.331	EPSD	COSMIC	5.915	Down-regulation
CMGC_MAPK_p38_MAPK14_ST	Q06413	MEF2C	Q16539	MAPK14	S419	E415D	415	Missense	distal	-4	no	14.517	15.309	EPSD	COSMIC	5.915	Up-regulation
CMGC_MAPK_p38_MAPK14_ST	Q06413	MEF2C	Q16539	MAPK14	S419	R413H	413	Missense	distal	-6	no	14.517	13.554	EPSD	COSMIC	5.915	Down-regulation
CMGC_MAPK_p38_MAPK14_ST	Q06413	MEF2C	Q16539	MAPK14	S419	R418G	418	Missense	proximal	-1	no	14.517	14.837	EPSD	COSMIC	5.915	Up-regulation
CMGC_MAPK_p38_MAPK14_ST	Q06413	MEF2C	Q16539	MAPK14	S419	S419L	419	Missense	central	0	yes	14.517	0.000	EPSD	COSMIC	5.915	Loss
CMGC_MAPK_p38_MAPK14_ST	Q06413	MEF2C	Q16539	MAPK14	S419	S419N	419	Missense	central	0	yes	14.517	0.000	EPSD	COSMIC	5.915	Loss
CMGC_MAPK_p38_MAPK14_ST	Q06413	MEF2C	Q16539	MAPK14	S429	S430P	430	Missense	proximal	1	no	5.005	12.289	EPSD	COSMIC	5.915	Gain
CMGC_MAPK_p38_MAPK14_ST	Q06413	MEF2C	Q16539	MAPK14	S445	S445L	445	Missense	central	0	yes	8.665	0.000	EPSD	COSMIC	5.915	Loss
CMGC_MAPK_p38_MAPK14_ST	Q06413	MEF2C	Q16539	MAPK14	S445	R440W	440	Missense	distal	-5	no	8.665	9.411	EPSD	COSMIC	5.915	Up-regulation
CMGC_MAPK_p38_MAPK14_ST	Q06413	MEF2C	Q16539	MAPK14	S445	S445F	445	Missense	central	0	yes	8.665	0.000	EPSD	COSMIC	5.915	Loss
CMGC_MAPK_p38_MAPK14_ST	Q06413	MEF2C	Q16539	MAPK14	S445	P452H	452	Missense	distal	7	no	8.665	8.387	EPSD	COSMIC	5.915	Down-regulation
CMGC_MAPK_p38_MAPK14_ST	Q06413	MEF2C	Q16539	MAPK14	S445	E442K	442	Missense	distal	-3	no	8.665	8.273	EPSD	COSMIC;GDSC;CCLE	5.915	Down-regulation
CMGC_MAPK_p38_MAPK14_ST	Q06413	MEF2C	Q16539	MAPK14	S445	D438Y	438	Missense	distal	-7	no	8.665	8.535	EPSD	COSMIC	5.915	Down-regulation
CMGC_MAPK_p38_MAPK14_ST	Q06413	MEF2C	Q16539	MAPK14	S445	R451K	451	Missense	distal	6	no	8.665	8.740	EPSD	COSMIC	5.915	Up-regulation
CMGC_MAPK_p38_MAPK14_ST	Q06413	MEF2C	Q16539	MAPK14	S445	R440K	440	Missense	distal	-5	no	8.665	8.530	EPSD	COSMIC	5.915	Down-regulation
CMGC_MAPK_p38_MAPK14_ST	Q06413	MEF2C	Q16539	MAPK14	S453	E456K	456	Missense	distal	3	no	11.833	11.881	EPSD	COSMIC	5.915	Up-regulation
CMGC_MAPK_p38_MAPK14_ST	Q06413	MEF2C	Q16539	MAPK14	S453	R457T	457	Missense	distal	4	no	11.833	12.289	EPSD	COSMIC	5.915	Up-regulation
CMGC_MAPK_p38_MAPK14_ST	Q06413	MEF2C	Q16539	MAPK14	S453	P452H	452	Missense	proximal	-1	no	11.833	11.788	EPSD	COSMIC	5.915	Down-regulation
CMGC_MAPK_p38_MAPK14_ST	Q06413	MEF2C	Q16539	MAPK14	S453	S453L	453	Missense	central	0	yes	11.833	0.000	EPSD	COSMIC	5.915	Loss
CMGC_MAPK_p38_MAPK14_ST	Q06413	MEF2C	Q16539	MAPK14	S453	E458K	458	Missense	distal	5	no	11.833	11.266	EPSD	COSMIC	5.915	Down-regulation
CMGC_MAPK_p38_MAPK14_ST	Q06413	MEF2C	Q16539	MAPK14	S453	R451K	451	Missense	proximal	-2	no	11.833	11.230	EPSD	COSMIC	5.915	Down-regulation
CMGC_MAPK_p38_MAPK14_ST	Q06413	MEF2C	Q16539	MAPK14	S453	R457K	457	Missense	distal	4	no	11.833	12.584	EPSD	COSMIC	5.915	Up-regulation
CMGC_MAPK_p38_MAPK14_ST	Q06413	MEF2C	Q16539	MAPK14	S453	S459N	459	Missense	distal	6	no	11.833	11.813	EPSD	COSMIC	5.915	Down-regulation
CMGC_MAPK_p38_MAPK14_ST	Q06413	MEF2C	Q16539	MAPK14	S459	E456K	456	Missense	distal	-3	no	12.470	12.077	EPSD	COSMIC	5.915	Down-regulation
CMGC_MAPK_p38_MAPK14_ST	Q06413	MEF2C	Q16539	MAPK14	S459	R457T	457	Missense	proximal	-2	no	12.470	12.438	EPSD	COSMIC	5.915	Down-regulation
CMGC_MAPK_p38_MAPK14_ST	Q06413	MEF2C	Q16539	MAPK14	S459	R464C	464	Missense	distal	5	no	12.470	11.600	EPSD	COSMIC	5.915	Down-regulation
CMGC_MAPK_p38_MAPK14_ST	Q06413	MEF2C	Q16539	MAPK14	S459	P452H	452	Missense	distal	-7	no	12.470	12.094	EPSD	COSMIC	5.915	Down-regulation
CMGC_MAPK_p38_MAPK14_ST	Q06413	MEF2C	Q16539	MAPK14	S459	M465I	465	Missense	distal	6	no	12.470	12.210	EPSD	COSMIC	5.915	Down-regulation
CMGC_MAPK_p38_MAPK14_ST	Q06413	MEF2C	Q16539	MAPK14	S459	S453L	453	Missense	distal	-6	no	12.470	11.250	EPSD	COSMIC	5.915	Down-regulation
CMGC_MAPK_p38_MAPK14_ST	Q06413	MEF2C	Q16539	MAPK14	S459	E458K	458	Missense	proximal	-1	no	12.470	12.531	EPSD	COSMIC	5.915	Up-regulation
CMGC_MAPK_p38_MAPK14_ST	Q06413	MEF2C	Q16539	MAPK14	S459	R457K	457	Missense	proximal	-2	no	12.470	11.867	EPSD	COSMIC	5.915	Down-regulation
CMGC_MAPK_p38_MAPK14_ST	Q06413	MEF2C	Q16539	MAPK14	S459	S459N	459	Missense	central	0	yes	12.470	0.000	EPSD	COSMIC	5.915	Loss
CMGC_MAPK_p38_MAPK14_ST	P06702	S100A9	Q16539	MAPK14	T113	G108C	108	Missense	distal	-5	no	12.598	12.918	PhosphoSitePlus	COSMIC	5.915	Up-regulation
CMGC_MAPK_p38_MAPK14_ST	Q8NHW3	MAFA	Q16539	MAPK14	S14	L11P	11	Missense	distal	-3	no	9.437	10.405	EPSD	COSMIC	5.915	Up-regulation
CMGC_MAPK_p38_MAPK14_ST	Q8NHW3	MAFA	Q16539	MAPK14	T134	N127K	127	Missense	distal	-7	no	11.010	11.318	EPSD;PhosphoSitePlus	COSMIC	5.915	Up-regulation
CMGC_MAPK_p38_MAPK14_ST	Q14934	NFATC4	Q16539	MAPK14	S73	P75H	75	Missense	proximal	2	no	10.251	10.099	EPSD	COSMIC	5.915	Down-regulation
CMGC_MAPK_p38_MAPK14_ST	Q14934	NFATC4	Q16539	MAPK14	S73	P66H	66	Missense	distal	-7	no	10.251	9.875	EPSD	COSMIC	5.915	Down-regulation
CMGC_MAPK_p38_MAPK14_ST	Q14934	NFATC4	Q16539	MAPK14	S73	P66A	66	Missense	distal	-7	no	10.251	10.451	EPSD	COSMIC	5.915	Up-regulation
CMGC_MAPK_p38_MAPK14_ST	Q14934	NFATC4	Q16539	MAPK14	S73	P69L	69	Missense	distal	-4	no	10.251	10.763	EPSD	COSMIC	5.915	Up-regulation
CMGC_MAPK_p38_MAPK14_ST	Q14934	NFATC4	Q16539	MAPK14	S73	R77Q	77	Missense	distal	4	no	10.251	10.047	EPSD	COSMIC	5.915	Down-regulation
CMGC_MAPK_p38_MAPK14_ST	Q14934	NFATC4	Q16539	MAPK14	S73	P78A	78	Missense	distal	5	no	10.251	10.063	EPSD	COSMIC	5.915	Down-regulation
CMGC_MAPK_p38_MAPK14_ST	Q14934	NFATC4	Q16539	MAPK14	S73	S73L	73	Missense	central	0	yes	10.251	0.000	EPSD	COSMIC	5.915	Loss
CMGC_MAPK_p38_MAPK14_ST	Q14934	NFATC4	Q16539	MAPK14	S122	P125H	125	Missense	distal	3	no	11.903	11.961	EPSD	COSMIC	5.915	Up-regulation
CMGC_MAPK_p38_MAPK14_ST	Q14934	NFATC4	Q16539	MAPK14	S122	P128S	128	Missense	distal	6	no	11.903	11.891	EPSD	COSMIC	5.915	Down-regulation
CMGC_MAPK_p38_MAPK14_ST	Q14934	NFATC4	Q16539	MAPK14	S122	S122C	122	Missense	central	0	yes	11.903	0.000	EPSD	COSMIC	5.915	Loss
CMGC_MAPK_p38_MAPK14_ST	Q14934	NFATC4	Q16539	MAPK14	S122	S120Y	120	Missense	proximal	-2	no	11.903	11.905	EPSD	COSMIC	5.915	Up-regulation
CMGC_MAPK_p38_MAPK14_ST	Q14934	NFATC4	Q16539	MAPK14	S122	P123S	123	Missense	proximal	1	no	11.903	4.619	EPSD	COSMIC	5.915	Loss
CMGC_MAPK_p38_MAPK14_ST	Q14934	NFATC4	Q16539	MAPK14	S122	P125Q	125	Missense	distal	3	no	11.903	11.931	EPSD	COSMIC	5.915	Up-regulation
CMGC_MAPK_p38_MAPK14_ST	Q14934	NFATC4	Q16539	MAPK14	S122	P127L	127	Missense	distal	5	no	11.903	11.406	EPSD	COSMIC	5.915	Down-regulation
CMGC_MAPK_p38_MAPK14_ST	Q14934	NFATC4	Q16539	MAPK14	S122	T124M	124	Missense	proximal	2	no	11.903	11.884	EPSD	COSMIC	5.915	Down-regulation
CMGC_MAPK_p38_MAPK14_ST	Q14934	NFATC4	Q16539	MAPK14	T124	P125H	125	Missense	proximal	1	no	8.997	-4.657	EPSD	COSMIC	5.915	Loss
CMGC_MAPK_p38_MAPK14_ST	Q14934	NFATC4	Q16539	MAPK14	T124	P128S	128	Missense	distal	4	no	8.997	9.437	EPSD	COSMIC	5.915	Up-regulation
CMGC_MAPK_p38_MAPK14_ST	Q14934	NFATC4	Q16539	MAPK14	T124	S122C	122	Missense	proximal	-2	no	8.997	7.862	EPSD	COSMIC	5.915	Down-regulation
CMGC_MAPK_p38_MAPK14_ST	Q14934	NFATC4	Q16539	MAPK14	T124	S120Y	120	Missense	distal	-4	no	8.997	8.993	EPSD	COSMIC	5.915	Down-regulation
CMGC_MAPK_p38_MAPK14_ST	Q14934	NFATC4	Q16539	MAPK14	T124	P123S	123	Missense	proximal	-1	no	8.997	8.905	EPSD	COSMIC	5.915	Down-regulation
CMGC_MAPK_p38_MAPK14_ST	Q14934	NFATC4	Q16539	MAPK14	T124	P125Q	125	Missense	proximal	1	no	8.997	1.789	EPSD	COSMIC	5.915	Loss
CMGC_MAPK_p38_MAPK14_ST	Q14934	NFATC4	Q16539	MAPK14	T124	P127L	127	Missense	distal	3	no	8.997	9.031	EPSD	COSMIC	5.915	Up-regulation
CMGC_MAPK_p38_MAPK14_ST	Q14934	NFATC4	Q16539	MAPK14	T124	A130V	130	Missense	distal	6	no	8.997	8.702	EPSD	COSMIC	5.915	Down-regulation
CMGC_MAPK_p38_MAPK14_ST	Q14934	NFATC4	Q16539	MAPK14	T124	T124M	124	Missense	central	0	yes	8.997	0.000	EPSD	COSMIC	5.915	Loss
CMGC_MAPK_p38_MAPK14_ST	Q14934	NFATC4	Q16539	MAPK14	S142	P148S	148	Missense	distal	6	no	9.822	9.810	EPSD	COSMIC	5.915	Down-regulation
CMGC_MAPK_p38_MAPK14_ST	Q14934	NFATC4	Q16539	MAPK14	S142	G141W	141	Missense	proximal	-1	no	9.822	9.790	EPSD	COSMIC	5.915	Down-regulation
CMGC_MAPK_p38_MAPK14_ST	Q14934	NFATC4	Q16539	MAPK14	S142	R144I	144	Missense	proximal	2	no	9.822	9.488	EPSD	COSMIC	5.915	Down-regulation
CMGC_MAPK_p38_MAPK14_ST	Q14934	NFATC4	Q16539	MAPK14	S142	P149Q	149	Missense	distal	7	no	9.822	9.885	EPSD	COSMIC	5.915	Up-regulation
CMGC_MAPK_p38_MAPK14_ST	Q14934	NFATC4	Q16539	MAPK14	S142	R144K	144	Missense	proximal	2	no	9.822	9.619	EPSD	COSMIC	5.915	Down-regulation
CMGC_MAPK_p38_MAPK14_ST	Q14934	NFATC4	Q16539	MAPK14	S142	W138L	138	Missense	distal	-4	no	9.822	9.782	EPSD	COSMIC	5.915	Down-regulation
CMGC_MAPK_p38_MAPK14_ST	Q14934	NFATC4	Q16539	MAPK14	S168	G163W	163	Missense	distal	-5	no	13.791	14.374	PhosphoSitePlus;EPSD	COSMIC;GDSC;CCLE	5.915	Up-regulation
CMGC_MAPK_p38_MAPK14_ST	Q14934	NFATC4	Q16539	MAPK14	S168	S168N	168	Missense	central	0	yes	13.791	0.000	PhosphoSitePlus;EPSD	COSMIC	5.915	Loss
CMGC_MAPK_p38_MAPK14_ST	Q14934	NFATC4	Q16539	MAPK14	S168	G163R	163	Missense	distal	-5	no	13.791	13.628	PhosphoSitePlus;EPSD	COSMIC	5.915	Down-regulation
CMGC_MAPK_p38_MAPK14_ST	Q14934	NFATC4	Q16539	MAPK14	S168	G162V	162	Missense	distal	-6	no	13.791	13.241	PhosphoSitePlus;EPSD	COSMIC	5.915	Down-regulation
CMGC_MAPK_p38_MAPK14_ST	Q14934	NFATC4	Q16539	MAPK14	S170	G163W	163	Missense	distal	-7	no	12.606	11.765	EPSD;PhosphoSitePlus	COSMIC;GDSC;CCLE	5.915	Down-regulation
CMGC_MAPK_p38_MAPK14_ST	Q14934	NFATC4	Q16539	MAPK14	S170	S168N	168	Missense	proximal	-2	no	12.606	11.920	EPSD;PhosphoSitePlus	COSMIC	5.915	Down-regulation
CMGC_MAPK_p38_MAPK14_ST	Q14934	NFATC4	Q16539	MAPK14	S170	G163R	163	Missense	distal	-7	no	12.606	12.505	EPSD;PhosphoSitePlus	COSMIC	5.915	Down-regulation
CMGC_MAPK_p38_MAPK14_ST	Q14934	NFATC4	Q16539	MAPK14	S173	S168N	168	Missense	distal	-5	no	5.611	6.075	EPSD	COSMIC	5.915	Gain
CMGC_MAPK_p38_MAPK14_ST	Q14934	NFATC4	Q16539	MAPK14	S213	R219I	219	Missense	distal	6	no	12.340	12.129	EPSD	COSMIC	5.915	Down-regulation
CMGC_MAPK_p38_MAPK14_ST	Q14934	NFATC4	Q16539	MAPK14	S213	R208C	208	Missense	distal	-5	no	12.340	12.822	EPSD	COSMIC	5.915	Up-regulation
CMGC_MAPK_p38_MAPK14_ST	Q14934	NFATC4	Q16539	MAPK14	S213	S217L	217	Missense	distal	4	no	12.340	11.261	EPSD	COSMIC;CCLE	5.915	Down-regulation
CMGC_MAPK_p38_MAPK14_ST	Q14934	NFATC4	Q16539	MAPK14	S213	R219Q	219	Missense	distal	6	no	12.340	12.351	EPSD	COSMIC	5.915	Up-regulation
CMGC_MAPK_p38_MAPK14_ST	Q14934	NFATC4	Q16539	MAPK14	S213	S207F	207	Missense	distal	-6	no	12.340	10.575	EPSD	COSMIC	5.915	Down-regulation
CMGC_MAPK_p38_MAPK14_ST	Q14934	NFATC4	Q16539	MAPK14	S213	P216L	216	Missense	distal	3	no	12.340	12.373	EPSD	COSMIC	5.915	Up-regulation
CMGC_MAPK_p38_MAPK14_ST	Q14934	NFATC4	Q16539	MAPK14	S213	P214Q	214	Missense	proximal	1	no	12.340	5.131	EPSD	COSMIC	5.915	Loss
CMGC_MAPK_p38_MAPK14_ST	Q14934	NFATC4	Q16539	MAPK14	S213	A206T	206	Missense	distal	-7	no	12.340	12.157	EPSD	COSMIC	5.915	Down-regulation
CMGC_MAPK_p38_MAPK14_ST	Q14934	NFATC4	Q16539	MAPK14	S217	R219I	219	Missense	proximal	2	no	10.934	10.600	EPSD	COSMIC	5.915	Down-regulation
CMGC_MAPK_p38_MAPK14_ST	Q14934	NFATC4	Q16539	MAPK14	S217	S217L	217	Missense	central	0	yes	10.934	0.000	EPSD	COSMIC;CCLE	5.915	Loss
CMGC_MAPK_p38_MAPK14_ST	Q14934	NFATC4	Q16539	MAPK14	S217	R219Q	219	Missense	proximal	2	no	10.934	10.508	EPSD	COSMIC	5.915	Down-regulation
CMGC_MAPK_p38_MAPK14_ST	Q14934	NFATC4	Q16539	MAPK14	S217	P216L	216	Missense	proximal	-1	no	10.934	11.120	EPSD	COSMIC	5.915	Up-regulation
CMGC_MAPK_p38_MAPK14_ST	Q14934	NFATC4	Q16539	MAPK14	S217	P214Q	214	Missense	distal	-3	no	10.934	10.431	EPSD	COSMIC	5.915	Down-regulation
CMGC_MAPK_p38_MAPK14_ST	Q14934	NFATC4	Q16539	MAPK14	S217	P224T	224	Missense	distal	7	no	10.934	10.835	EPSD	COSMIC	5.915	Down-regulation
CMGC_MAPK_p38_MAPK14_ST	Q14934	NFATC4	Q16539	MAPK14	S217	R223W	223	Missense	distal	6	no	10.934	10.671	EPSD	COSMIC	5.915	Down-regulation
CMGC_MAPK_p38_MAPK14_ST	Q14934	NFATC4	Q16539	MAPK14	S221	R219I	219	Missense	proximal	-2	no	9.476	9.346	EPSD	COSMIC	5.915	Down-regulation
CMGC_MAPK_p38_MAPK14_ST	Q14934	NFATC4	Q16539	MAPK14	S221	P227Q	227	Missense	distal	6	no	9.476	9.475	EPSD	COSMIC	5.915	Down-regulation
CMGC_MAPK_p38_MAPK14_ST	Q14934	NFATC4	Q16539	MAPK14	S221	P227H	227	Missense	distal	6	no	9.476	9.356	EPSD	COSMIC	5.915	Down-regulation
CMGC_MAPK_p38_MAPK14_ST	Q14934	NFATC4	Q16539	MAPK14	S221	E228K	228	Missense	distal	7	no	9.476	8.769	EPSD	COSMIC	5.915	Down-regulation
CMGC_MAPK_p38_MAPK14_ST	Q14934	NFATC4	Q16539	MAPK14	S221	S217L	217	Missense	distal	-4	no	9.476	10.075	EPSD	COSMIC;CCLE	5.915	Up-regulation
CMGC_MAPK_p38_MAPK14_ST	Q14934	NFATC4	Q16539	MAPK14	S221	R219Q	219	Missense	proximal	-2	no	9.476	9.149	EPSD	COSMIC	5.915	Down-regulation
CMGC_MAPK_p38_MAPK14_ST	Q14934	NFATC4	Q16539	MAPK14	S221	P216L	216	Missense	distal	-5	no	9.476	9.757	EPSD	COSMIC	5.915	Up-regulation
CMGC_MAPK_p38_MAPK14_ST	Q14934	NFATC4	Q16539	MAPK14	S221	P214Q	214	Missense	distal	-7	no	9.476	9.300	EPSD	COSMIC	5.915	Down-regulation
CMGC_MAPK_p38_MAPK14_ST	Q14934	NFATC4	Q16539	MAPK14	S221	P224T	224	Missense	distal	3	no	9.476	9.449	EPSD	COSMIC	5.915	Down-regulation
CMGC_MAPK_p38_MAPK14_ST	Q14934	NFATC4	Q16539	MAPK14	S221	R223W	223	Missense	proximal	2	no	9.476	8.978	EPSD	COSMIC	5.915	Down-regulation
CMGC_MAPK_p38_MAPK14_ST	Q14934	NFATC4	Q16539	MAPK14	S221	T226S	226	Missense	distal	5	no	9.476	9.642	EPSD	COSMIC	5.915	Up-regulation
CMGC_MAPK_p38_MAPK14_ST	Q14934	NFATC4	Q16539	MAPK14	T226	R219I	219	Missense	distal	-7	no	10.758	10.506	EPSD	COSMIC	5.915	Down-regulation
CMGC_MAPK_p38_MAPK14_ST	Q14934	NFATC4	Q16539	MAPK14	T226	P227Q	227	Missense	proximal	1	no	10.758	3.549	EPSD	COSMIC	5.915	Loss
CMGC_MAPK_p38_MAPK14_ST	Q14934	NFATC4	Q16539	MAPK14	T226	P227H	227	Missense	proximal	1	no	10.758	-2.896	EPSD	COSMIC	5.915	Loss
CMGC_MAPK_p38_MAPK14_ST	Q14934	NFATC4	Q16539	MAPK14	T226	E228K	228	Missense	proximal	2	no	10.758	10.444	EPSD	COSMIC	5.915	Down-regulation
CMGC_MAPK_p38_MAPK14_ST	Q14934	NFATC4	Q16539	MAPK14	T226	R219Q	219	Missense	distal	-7	no	10.758	10.664	EPSD	COSMIC	5.915	Down-regulation
CMGC_MAPK_p38_MAPK14_ST	Q14934	NFATC4	Q16539	MAPK14	T226	P224T	224	Missense	proximal	-2	no	10.758	10.038	EPSD	COSMIC	5.915	Down-regulation
CMGC_MAPK_p38_MAPK14_ST	Q14934	NFATC4	Q16539	MAPK14	T226	R223W	223	Missense	distal	-3	no	10.758	8.401	EPSD	COSMIC	5.915	Down-regulation
CMGC_MAPK_p38_MAPK14_ST	Q14934	NFATC4	Q16539	MAPK14	T226	W231S	231	Missense	distal	5	no	10.758	11.962	EPSD	COSMIC	5.915	Up-regulation
CMGC_MAPK_p38_MAPK14_ST	Q14934	NFATC4	Q16539	MAPK14	S237	G235S	235	Missense	proximal	-2	no	10.013	10.463	EPSD	COSMIC	5.915	Up-regulation
CMGC_MAPK_p38_MAPK14_ST	Q14934	NFATC4	Q16539	MAPK14	S237	R241L	241	Missense	distal	4	no	10.013	9.651	EPSD	COSMIC	5.915	Down-regulation
CMGC_MAPK_p38_MAPK14_ST	Q14934	NFATC4	Q16539	MAPK14	S237	R241Q	241	Missense	distal	4	no	10.013	9.808	EPSD	COSMIC	5.915	Down-regulation
CMGC_MAPK_p38_MAPK14_ST	Q14934	NFATC4	Q16539	MAPK14	S237	W231S	231	Missense	distal	-6	no	10.013	11.437	EPSD	COSMIC	5.915	Up-regulation
CMGC_MAPK_p38_MAPK14_ST	Q14934	NFATC4	Q16539	MAPK14	S246	P253L	253	Missense	distal	7	no	6.355	6.192	EPSD	COSMIC	5.915	Down-regulation
CMGC_MAPK_p38_MAPK14_ST	Q14934	NFATC4	Q16539	MAPK14	S246	R241L	241	Missense	distal	-5	no	6.355	6.866	EPSD	COSMIC	5.915	Up-regulation
CMGC_MAPK_p38_MAPK14_ST	Q14934	NFATC4	Q16539	MAPK14	S246	R241Q	241	Missense	distal	-5	no	6.355	6.313	EPSD	COSMIC	5.915	Down-regulation
CMGC_MAPK_p38_MAPK14_ST	Q14934	NFATC4	Q16539	MAPK14	T256	P257S	257	Missense	proximal	1	no	9.714	2.430	EPSD	COSMIC	5.915	Loss
CMGC_MAPK_p38_MAPK14_ST	Q14934	NFATC4	Q16539	MAPK14	T256	R261W	261	Missense	distal	5	no	9.714	8.820	EPSD	COSMIC	5.915	Down-regulation
CMGC_MAPK_p38_MAPK14_ST	Q14934	NFATC4	Q16539	MAPK14	T256	P253L	253	Missense	distal	-3	no	9.714	8.746	EPSD	COSMIC	5.915	Down-regulation
CMGC_MAPK_p38_MAPK14_ST	Q14934	NFATC4	Q16539	MAPK14	T256	P260Q	260	Missense	distal	4	no	9.714	9.232	EPSD	COSMIC	5.915	Down-regulation
CMGC_MAPK_p38_MAPK14_ST	Q14934	NFATC4	Q16539	MAPK14	T256	R261Q	261	Missense	distal	5	no	9.714	9.365	EPSD	COSMIC	5.915	Down-regulation
CMGC_MAPK_p38_MAPK14_ST	Q14934	NFATC4	Q16539	MAPK14	T256	S259F	259	Missense	distal	3	no	9.714	9.822	EPSD	COSMIC	5.915	Up-regulation
CMGC_MAPK_p38_MAPK14_ST	Q14934	NFATC4	Q16539	MAPK14	S259	P257S	257	Missense	proximal	-2	no	11.260	10.771	EPSD	COSMIC	5.915	Down-regulation
CMGC_MAPK_p38_MAPK14_ST	Q14934	NFATC4	Q16539	MAPK14	S259	R261W	261	Missense	proximal	2	no	11.260	10.761	EPSD	COSMIC	5.915	Down-regulation
CMGC_MAPK_p38_MAPK14_ST	Q14934	NFATC4	Q16539	MAPK14	S259	P253L	253	Missense	distal	-6	no	11.260	10.647	EPSD	COSMIC	5.915	Down-regulation
CMGC_MAPK_p38_MAPK14_ST	Q14934	NFATC4	Q16539	MAPK14	S259	P260Q	260	Missense	proximal	1	no	11.260	4.051	EPSD	COSMIC	5.915	Loss
CMGC_MAPK_p38_MAPK14_ST	Q14934	NFATC4	Q16539	MAPK14	S259	R261Q	261	Missense	proximal	2	no	11.260	10.833	EPSD	COSMIC	5.915	Down-regulation
CMGC_MAPK_p38_MAPK14_ST	Q14934	NFATC4	Q16539	MAPK14	S259	P265L	265	Missense	distal	6	no	11.260	11.121	EPSD	COSMIC	5.915	Down-regulation
CMGC_MAPK_p38_MAPK14_ST	Q14934	NFATC4	Q16539	MAPK14	S259	S259F	259	Missense	central	0	yes	11.260	0.000	EPSD	COSMIC	5.915	Loss
CMGC_MAPK_p38_MAPK14_ST	Q14934	NFATC4	Q16539	MAPK14	S264	P257S	257	Missense	distal	-7	no	13.389	13.476	EPSD	COSMIC	5.915	Up-regulation
CMGC_MAPK_p38_MAPK14_ST	Q14934	NFATC4	Q16539	MAPK14	S264	R261W	261	Missense	distal	-3	no	13.389	11.032	EPSD	COSMIC	5.915	Down-regulation
CMGC_MAPK_p38_MAPK14_ST	Q14934	NFATC4	Q16539	MAPK14	S264	P260Q	260	Missense	distal	-4	no	13.389	13.680	EPSD	COSMIC	5.915	Up-regulation
CMGC_MAPK_p38_MAPK14_ST	Q14934	NFATC4	Q16539	MAPK14	S264	R261Q	261	Missense	distal	-3	no	13.389	11.610	EPSD	COSMIC	5.915	Down-regulation
CMGC_MAPK_p38_MAPK14_ST	Q14934	NFATC4	Q16539	MAPK14	S264	P265L	265	Missense	proximal	1	no	13.389	5.338	EPSD	COSMIC	5.915	Loss
CMGC_MAPK_p38_MAPK14_ST	Q14934	NFATC4	Q16539	MAPK14	S264	Y271H	271	Missense	distal	7	no	13.389	12.847	EPSD	COSMIC	5.915	Down-regulation
CMGC_MAPK_p38_MAPK14_ST	Q14934	NFATC4	Q16539	MAPK14	S264	R269Q	269	Missense	distal	5	no	13.389	13.040	EPSD	COSMIC	5.915	Down-regulation
CMGC_MAPK_p38_MAPK14_ST	Q14934	NFATC4	Q16539	MAPK14	S264	R269W	269	Missense	distal	5	no	13.389	12.495	EPSD	COSMIC	5.915	Down-regulation
CMGC_MAPK_p38_MAPK14_ST	Q14934	NFATC4	Q16539	MAPK14	S264	R270H	270	Missense	distal	6	no	13.389	13.282	EPSD	COSMIC	5.915	Down-regulation
CMGC_MAPK_p38_MAPK14_ST	Q14934	NFATC4	Q16539	MAPK14	S264	R270C	270	Missense	distal	6	no	13.389	13.115	EPSD	COSMIC	5.915	Down-regulation
CMGC_MAPK_p38_MAPK14_ST	Q14934	NFATC4	Q16539	MAPK14	S264	S259F	259	Missense	distal	-5	no	13.389	14.174	EPSD	COSMIC	5.915	Up-regulation
CMGC_MAPK_p38_MAPK14_ST	Q14934	NFATC4	Q16539	MAPK14	T276	P277Q	277	Missense	proximal	1	no	13.404	6.196	EPSD	COSMIC	5.915	Down-regulation
CMGC_MAPK_p38_MAPK14_ST	Q14934	NFATC4	Q16539	MAPK14	T276	S272F	272	Missense	distal	-4	no	13.404	14.108	EPSD	COSMIC	5.915	Up-regulation
CMGC_MAPK_p38_MAPK14_ST	Q14934	NFATC4	Q16539	MAPK14	T276	G275S	275	Missense	proximal	-1	no	13.404	13.191	EPSD	COSMIC	5.915	Down-regulation
CMGC_MAPK_p38_MAPK14_ST	Q14934	NFATC4	Q16539	MAPK14	T276	S273L	273	Missense	distal	-3	no	13.404	11.673	EPSD	COSMIC	5.915	Down-regulation
CMGC_MAPK_p38_MAPK14_ST	Q14934	NFATC4	Q16539	MAPK14	T276	P282A	282	Missense	distal	6	no	13.404	13.447	EPSD	COSMIC	5.915	Up-regulation
CMGC_MAPK_p38_MAPK14_ST	Q14934	NFATC4	Q16539	MAPK14	T276	Y271H	271	Missense	distal	-5	no	13.404	13.717	EPSD	COSMIC	5.915	Up-regulation
CMGC_MAPK_p38_MAPK14_ST	Q14934	NFATC4	Q16539	MAPK14	T276	R269Q	269	Missense	distal	-7	no	13.404	13.310	EPSD	COSMIC	5.915	Down-regulation
CMGC_MAPK_p38_MAPK14_ST	Q14934	NFATC4	Q16539	MAPK14	T276	S272P	272	Missense	distal	-4	no	13.404	13.492	EPSD	COSMIC	5.915	Up-regulation
CMGC_MAPK_p38_MAPK14_ST	Q14934	NFATC4	Q16539	MAPK14	T276	R269W	269	Missense	distal	-7	no	13.404	12.665	EPSD	COSMIC	5.915	Down-regulation
CMGC_MAPK_p38_MAPK14_ST	Q14934	NFATC4	Q16539	MAPK14	T276	S281F	281	Missense	distal	5	no	13.404	11.962	EPSD	COSMIC	5.915	Down-regulation
CMGC_MAPK_p38_MAPK14_ST	Q14934	NFATC4	Q16539	MAPK14	T276	R270H	270	Missense	distal	-6	no	13.404	12.441	EPSD	COSMIC	5.915	Down-regulation
CMGC_MAPK_p38_MAPK14_ST	Q14934	NFATC4	Q16539	MAPK14	T276	R270C	270	Missense	distal	-6	no	13.404	12.218	EPSD	COSMIC	5.915	Down-regulation
CMGC_MAPK_p38_MAPK14_ST	Q14934	NFATC4	Q16539	MAPK14	T276	S274L	274	Missense	proximal	-2	no	13.404	12.513	EPSD	COSMIC	5.915	Down-regulation
CMGC_MAPK_p38_MAPK14_ST	Q14934	NFATC4	Q16539	MAPK14	S279	R286W	286	Missense	distal	7	no	5.996	5.307	EPSD	COSMIC	5.915	Loss
CMGC_MAPK_p38_MAPK14_ST	Q14934	NFATC4	Q16539	MAPK14	S279	P277Q	277	Missense	proximal	-2	no	5.996	4.981	EPSD	COSMIC	5.915	Loss
CMGC_MAPK_p38_MAPK14_ST	Q14934	NFATC4	Q16539	MAPK14	S279	S272F	272	Missense	distal	-7	no	5.996	5.250	EPSD	COSMIC	5.915	Loss
CMGC_MAPK_p38_MAPK14_ST	Q14934	NFATC4	Q16539	MAPK14	S279	S285P	285	Missense	distal	6	no	5.996	6.008	EPSD	COSMIC	5.915	Up-regulation
CMGC_MAPK_p38_MAPK14_ST	Q14934	NFATC4	Q16539	MAPK14	S279	G275S	275	Missense	distal	-4	no	5.996	5.998	EPSD	COSMIC	5.915	Up-regulation
CMGC_MAPK_p38_MAPK14_ST	Q14934	NFATC4	Q16539	MAPK14	S279	S273L	273	Missense	distal	-6	no	5.996	4.776	EPSD	COSMIC	5.915	Loss
CMGC_MAPK_p38_MAPK14_ST	Q14934	NFATC4	Q16539	MAPK14	S279	P282A	282	Missense	distal	3	no	5.996	5.970	EPSD	COSMIC	5.915	Down-regulation
CMGC_MAPK_p38_MAPK14_ST	Q14934	NFATC4	Q16539	MAPK14	S279	R286H	286	Missense	distal	7	no	5.996	5.462	EPSD	COSMIC	5.915	Loss
CMGC_MAPK_p38_MAPK14_ST	Q14934	NFATC4	Q16539	MAPK14	S279	S272P	272	Missense	distal	-7	no	5.996	5.909	EPSD	COSMIC	5.915	Loss
CMGC_MAPK_p38_MAPK14_ST	Q14934	NFATC4	Q16539	MAPK14	S279	S281F	281	Missense	proximal	2	no	5.996	5.330	EPSD	COSMIC	5.915	Loss
CMGC_MAPK_p38_MAPK14_ST	Q14934	NFATC4	Q16539	MAPK14	S279	S274L	274	Missense	distal	-5	no	5.996	6.725	EPSD	COSMIC	5.915	Up-regulation
CMGC_MAPK_p38_MAPK14_ST	Q14934	NFATC4	Q16539	MAPK14	S281	R286W	286	Missense	distal	5	no	12.859	11.965	EPSD	COSMIC	5.915	Down-regulation
CMGC_MAPK_p38_MAPK14_ST	Q14934	NFATC4	Q16539	MAPK14	S281	P277Q	277	Missense	distal	-4	no	12.859	13.151	EPSD	COSMIC	5.915	Up-regulation
CMGC_MAPK_p38_MAPK14_ST	Q14934	NFATC4	Q16539	MAPK14	S281	S285P	285	Missense	distal	4	no	12.859	12.420	EPSD	COSMIC	5.915	Down-regulation
CMGC_MAPK_p38_MAPK14_ST	Q14934	NFATC4	Q16539	MAPK14	S281	G275S	275	Missense	distal	-6	no	12.859	13.340	EPSD	COSMIC	5.915	Up-regulation
CMGC_MAPK_p38_MAPK14_ST	Q14934	NFATC4	Q16539	MAPK14	S281	G288W	288	Missense	distal	7	no	12.859	12.349	EPSD	COSMIC	5.915	Down-regulation
CMGC_MAPK_p38_MAPK14_ST	Q14934	NFATC4	Q16539	MAPK14	S281	P282A	282	Missense	proximal	1	no	12.859	6.541	EPSD	COSMIC	5.915	Down-regulation
CMGC_MAPK_p38_MAPK14_ST	Q14934	NFATC4	Q16539	MAPK14	S281	R286H	286	Missense	distal	5	no	12.859	12.165	EPSD	COSMIC	5.915	Down-regulation
CMGC_MAPK_p38_MAPK14_ST	Q14934	NFATC4	Q16539	MAPK14	S281	R287H	287	Missense	distal	6	no	12.859	12.752	EPSD	COSMIC	5.915	Down-regulation
CMGC_MAPK_p38_MAPK14_ST	Q14934	NFATC4	Q16539	MAPK14	S281	R287S	287	Missense	distal	6	no	12.859	12.860	EPSD	COSMIC	5.915	Up-regulation
CMGC_MAPK_p38_MAPK14_ST	Q14934	NFATC4	Q16539	MAPK14	S281	S281F	281	Missense	central	0	yes	12.859	0.000	EPSD	COSMIC	5.915	Loss
CMGC_MAPK_p38_MAPK14_ST	Q14934	NFATC4	Q16539	MAPK14	S281	S274L	274	Missense	distal	-7	no	12.859	12.579	EPSD	COSMIC	5.915	Down-regulation
CMGC_MAPK_p38_MAPK14_ST	Q14934	NFATC4	Q16539	MAPK14	S285	R286W	286	Missense	proximal	1	no	4.006	5.972	EPSD	COSMIC	5.915	Gain
CMGC_MAPK_p38_MAPK14_ST	Q14934	NFATC4	Q16539	MAPK14	S289	R286W	286	Missense	distal	-3	no	6.470	4.113	EPSD	COSMIC	5.915	Loss
CMGC_MAPK_p38_MAPK14_ST	Q14934	NFATC4	Q16539	MAPK14	S289	S285P	285	Missense	distal	-4	no	6.470	6.558	EPSD	COSMIC	5.915	Up-regulation
CMGC_MAPK_p38_MAPK14_ST	Q14934	NFATC4	Q16539	MAPK14	S289	G288W	288	Missense	proximal	-1	no	6.470	6.438	EPSD	COSMIC	5.915	Down-regulation
CMGC_MAPK_p38_MAPK14_ST	Q14934	NFATC4	Q16539	MAPK14	S289	P282A	282	Missense	distal	-7	no	6.470	6.671	EPSD	COSMIC	5.915	Up-regulation
CMGC_MAPK_p38_MAPK14_ST	Q14934	NFATC4	Q16539	MAPK14	S289	R286H	286	Missense	distal	-3	no	6.470	4.717	EPSD	COSMIC	5.915	Loss
CMGC_MAPK_p38_MAPK14_ST	Q14934	NFATC4	Q16539	MAPK14	S289	R287H	287	Missense	proximal	-2	no	6.470	4.892	EPSD	COSMIC	5.915	Loss
CMGC_MAPK_p38_MAPK14_ST	Q14934	NFATC4	Q16539	MAPK14	S289	R287S	287	Missense	proximal	-2	no	6.470	6.670	EPSD	COSMIC	5.915	Up-regulation
CMGC_MAPK_p38_MAPK14_ST	Q14934	NFATC4	Q16539	MAPK14	S289	G291R	291	Missense	proximal	2	no	6.470	6.554	EPSD	COSMIC	5.915	Up-regulation
CMGC_MAPK_p38_MAPK14_ST	Q14934	NFATC4	Q16539	MAPK14	S289	G294E	294	Missense	distal	5	no	6.470	6.688	EPSD	COSMIC	5.915	Up-regulation
CMGC_MAPK_p38_MAPK14_ST	Q14934	NFATC4	Q16539	MAPK14	S311	P314S	314	Missense	distal	3	no	9.701	9.661	EPSD	COSMIC	5.915	Down-regulation
CMGC_MAPK_p38_MAPK14_ST	Q14934	NFATC4	Q16539	MAPK14	S311	P312S	312	Missense	proximal	1	no	9.701	2.418	EPSD	COSMIC	5.915	Loss
CMGC_MAPK_p38_MAPK14_ST	Q14934	NFATC4	Q16539	MAPK14	S311	P304L	304	Missense	distal	-7	no	9.701	9.508	EPSD	COSMIC	5.915	Down-regulation
CMGC_MAPK_p38_MAPK14_ST	Q14934	NFATC4	Q16539	MAPK14	S311	D316Y	316	Missense	distal	5	no	9.701	9.966	EPSD	COSMIC	5.915	Up-regulation
CMGC_MAPK_p38_MAPK14_ST	Q14934	NFATC4	Q16539	MAPK14	S311	F315L	315	Missense	distal	4	no	9.701	10.197	EPSD	COSMIC;CCLE	5.915	Up-regulation
CMGC_MAPK_p38_MAPK14_ST	Q14934	NFATC4	Q16539	MAPK14	S334	R332W	332	Missense	proximal	-2	no	6.673	6.147	EPSD	COSMIC	5.915	Down-regulation
CMGC_MAPK_p38_MAPK14_ST	Q14934	NFATC4	Q16539	MAPK14	S334	S335P	335	Missense	proximal	1	no	6.673	13.957	EPSD	COSMIC	5.915	Up-regulation
CMGC_MAPK_p38_MAPK14_ST	Q14934	NFATC4	Q16539	MAPK14	S334	P327L	327	Missense	distal	-7	no	6.673	6.480	EPSD	COSMIC	5.915	Down-regulation
CMGC_MAPK_p38_MAPK14_ST	Q14934	NFATC4	Q16539	MAPK14	S334	R331Q	331	Missense	distal	-3	no	6.673	4.894	EPSD	COSMIC	5.915	Loss
CMGC_MAPK_p38_MAPK14_ST	Q14934	NFATC4	Q16539	MAPK14	S334	P327S	327	Missense	distal	-7	no	6.673	6.760	EPSD	COSMIC	5.915	Up-regulation
CMGC_MAPK_p38_MAPK14_ST	Q14934	NFATC4	Q16539	MAPK14	S334	R331W	331	Missense	distal	-3	no	6.673	4.316	EPSD	COSMIC	5.915	Loss
CMGC_MAPK_p38_MAPK14_ST	Q14934	NFATC4	Q16539	MAPK14	S334	K329R	329	Missense	distal	-5	no	6.673	6.808	EPSD	COSMIC	5.915	Up-regulation
CMGC_MAPK_p38_MAPK14_ST	Q14934	NFATC4	Q16539	MAPK14	S334	R332L	332	Missense	proximal	-2	no	6.673	5.981	EPSD	COSMIC	5.915	Down-regulation
CMGC_MAPK_p38_MAPK14_ST	Q14934	NFATC4	Q16539	MAPK14	S382	D376N	376	Missense	distal	-6	no	9.349	9.674	EPSD	COSMIC	5.915	Up-regulation
CMGC_MAPK_p38_MAPK14_ST	Q14934	NFATC4	Q16539	MAPK14	S382	V380A	380	Missense	proximal	-2	no	9.349	9.763	EPSD	COSMIC	5.915	Up-regulation
CMGC_MAPK_p38_MAPK14_ST	Q14934	NFATC4	Q16539	MAPK14	S382	P383T	383	Missense	proximal	1	no	9.349	1.895	EPSD	COSMIC	5.915	Loss
CMGC_MAPK_p38_MAPK14_ST	Q14934	NFATC4	Q16539	MAPK14	S382	S387F	387	Missense	distal	5	no	9.349	7.907	EPSD	COSMIC	5.915	Down-regulation
CMGC_MAPK_p38_MAPK14_ST	Q14934	NFATC4	Q16539	MAPK14	S382	D376Y	376	Missense	distal	-6	no	9.349	9.331	EPSD	COSMIC	5.915	Down-regulation
CMGC_MAPK_p38_MAPK14_ST	Q14934	NFATC4	Q16539	MAPK14	S395	P396T	396	Missense	proximal	1	no	11.551	4.098	EPSD	COSMIC	5.915	Loss
CMGC_MAPK_p38_MAPK14_ST	Q14934	NFATC4	Q16539	MAPK14	S395	A402V	402	Missense	distal	7	no	11.551	11.442	EPSD	COSMIC	5.915	Down-regulation
CMGC_MAPK_p38_MAPK14_ST	Q14934	NFATC4	Q16539	MAPK14	S395	R399K	399	Missense	distal	4	no	11.551	12.302	EPSD	COSMIC	5.915	Up-regulation
CMGC_MAPK_p38_MAPK14_ST	Q14934	NFATC4	Q16539	MAPK14	S395	G392V	392	Missense	distal	-3	no	11.551	10.576	EPSD	COSMIC	5.915	Down-regulation
CMGC_MAPK_p38_MAPK14_ST	Q14934	NFATC4	Q16539	MAPK14	S395	F398S	398	Missense	distal	3	no	11.551	11.443	EPSD	COSMIC	5.915	Down-regulation
CMGC_MAPK_p38_MAPK14_ST	Q14934	NFATC4	Q16539	MAPK14	S395	I391T	391	Missense	distal	-4	no	11.551	11.661	EPSD	COSMIC	5.915	Up-regulation
CMGC_MAPK_p38_MAPK14_ST	Q14934	NFATC4	Q16539	MAPK14	S395	S395I	395	Missense	central	0	yes	11.551	0.000	EPSD	COSMIC	5.915	Loss
CMGC_MAPK_p38_MAPK14_ST	Q14934	NFATC4	Q16539	MAPK14	S592	E589K	589	Missense	distal	-3	no	12.002	11.610	EPSD	COSMIC	5.915	Down-regulation
CMGC_MAPK_p38_MAPK14_ST	Q14934	NFATC4	Q16539	MAPK14	S592	S594L	594	Missense	proximal	2	no	12.002	11.513	EPSD	COSMIC	5.915	Down-regulation
CMGC_MAPK_p38_MAPK14_ST	Q14934	NFATC4	Q16539	MAPK14	S592	P586H	586	Missense	distal	-6	no	12.002	11.540	EPSD	COSMIC	5.915	Down-regulation
CMGC_MAPK_p38_MAPK14_ST	Q14934	NFATC4	Q16539	MAPK14	S592	P593S	593	Missense	proximal	1	no	12.002	4.718	EPSD	COSMIC	5.915	Loss
CMGC_MAPK_p38_MAPK14_ST	Q14934	NFATC4	Q16539	MAPK14	S592	R599I	599	Missense	distal	7	no	12.002	11.235	EPSD	COSMIC	5.915	Down-regulation
CMGC_MAPK_p38_MAPK14_ST	Q14934	NFATC4	Q16539	MAPK14	S592	S594R	594	Missense	proximal	2	no	12.002	11.857	EPSD	COSMIC	5.915	Down-regulation
CMGC_MAPK_p38_MAPK14_ST	Q14934	NFATC4	Q16539	MAPK14	S676	P677A	677	Missense	proximal	1	no	11.246	4.927	EPSD	COSMIC	5.915	Loss
CMGC_MAPK_p38_MAPK14_ST	Q14934	NFATC4	Q16539	MAPK14	S676	S676N	676	Missense	central	0	yes	11.246	0.000	EPSD	COSMIC	5.915	Loss
CMGC_MAPK_p38_MAPK14_ST	Q14934	NFATC4	Q16539	MAPK14	S676	G671W	671	Missense	distal	-5	no	11.246	11.829	EPSD	COSMIC	5.915	Up-regulation
CMGC_MAPK_p38_MAPK14_ST	Q14934	NFATC4	Q16539	MAPK14	S676	R675H	675	Missense	proximal	-1	no	11.246	11.401	EPSD	COSMIC;CCLE	5.915	Up-regulation
CMGC_MAPK_p38_MAPK14_ST	Q14934	NFATC4	Q16539	MAPK14	S676	R672W	672	Missense	distal	-4	no	11.246	11.875	EPSD	COSMIC	5.915	Up-regulation
CMGC_MAPK_p38_MAPK14_ST	Q14934	NFATC4	Q16539	MAPK14	S676	S669A	669	Missense	distal	-7	no	11.246	11.359	EPSD	COSMIC	5.915	Up-regulation
CMGC_MAPK_p38_MAPK14_ST	Q14934	NFATC4	Q16539	MAPK14	S676	G671R	671	Missense	distal	-5	no	11.246	11.083	EPSD	COSMIC	5.915	Down-regulation
CMGC_MAPK_p38_MAPK14_ST	Q14934	NFATC4	Q16539	MAPK14	S676	F683C	683	Missense	distal	7	no	11.246	11.551	EPSD	COSMIC	5.915	Up-regulation
CMGC_MAPK_p38_MAPK14_ST	Q14934	NFATC4	Q16539	MAPK14	S676	R675C	675	Missense	proximal	-1	no	11.246	11.509	EPSD	COSMIC	5.915	Up-regulation
CMGC_MAPK_p38_MAPK14_ST	Q14934	NFATC4	Q16539	MAPK14	S716	P723L	723	Missense	distal	7	no	11.261	11.098	EPSD	COSMIC	5.915	Down-regulation
CMGC_MAPK_p38_MAPK14_ST	Q14934	NFATC4	Q16539	MAPK14	S716	P721H	721	Missense	distal	5	no	11.261	10.706	EPSD	COSMIC	5.915	Down-regulation
CMGC_MAPK_p38_MAPK14_ST	Q14934	NFATC4	Q16539	MAPK14	S716	F709C	709	Missense	distal	-7	no	11.261	11.446	EPSD	COSMIC	5.915	Up-regulation
CMGC_MAPK_p38_MAPK14_ST	Q14934	NFATC4	Q16539	MAPK14	S716	R719K	719	Missense	distal	3	no	11.261	11.277	EPSD	COSMIC	5.915	Up-regulation
CMGC_MAPK_p38_MAPK14_ST	Q14934	NFATC4	Q16539	MAPK14	S716	P723S	723	Missense	distal	7	no	11.261	11.482	EPSD	COSMIC	5.915	Up-regulation
CMGC_MAPK_p38_MAPK14_ST	Q14934	NFATC4	Q16539	MAPK14	S819	G824C	824	Missense	distal	5	no	11.591	10.665	EPSD	COSMIC;CCLE	5.915	Down-regulation
CMGC_MAPK_p38_MAPK14_ST	Q14934	NFATC4	Q16539	MAPK14	S819	P817S	817	Missense	proximal	-2	no	11.591	11.102	EPSD	COSMIC	5.915	Down-regulation
CMGC_MAPK_p38_MAPK14_ST	Q14934	NFATC4	Q16539	MAPK14	S819	P820A	820	Missense	proximal	1	no	11.591	5.272	EPSD	COSMIC	5.915	Loss
CMGC_MAPK_p38_MAPK14_ST	Q14934	NFATC4	Q16539	MAPK14	S819	S819F	819	Missense	central	0	yes	11.591	0.000	EPSD	COSMIC	5.915	Loss
CMGC_MAPK_p38_MAPK14_ST	Q14934	NFATC4	Q16539	MAPK14	S819	A818V	818	Missense	proximal	-1	no	11.591	11.747	EPSD	COSMIC	5.915	Up-regulation
CMGC_MAPK_p38_MAPK14_ST	Q14934	NFATC4	Q16539	MAPK14	S819	A818S	818	Missense	proximal	-1	no	11.591	11.531	EPSD	COSMIC	5.915	Down-regulation
CMGC_MAPK_p38_MAPK14_ST	Q14934	NFATC4	Q16539	MAPK14	S819	P825S	825	Missense	distal	6	no	11.591	11.579	EPSD	COSMIC	5.915	Down-regulation
CMGC_MAPK_p38_MAPK14_ST	Q14934	NFATC4	Q16539	MAPK14	S819	P815H	815	Missense	distal	-4	no	11.591	11.725	EPSD	COSMIC	5.915	Up-regulation
CMGC_MAPK_p38_MAPK14_ST	Q14934	NFATC4	Q16539	MAPK14	S819	P813S	813	Missense	distal	-6	no	11.591	12.197	EPSD	COSMIC	5.915	Up-regulation
CMGC_MAPK_p38_MAPK14_ST	Q14934	NFATC4	Q16539	MAPK14	S819	E823A	823	Missense	distal	4	no	11.591	10.785	EPSD	COSMIC	5.915	Down-regulation
CMGC_MAPK_p38_MAPK14_ST	Q14934	NFATC4	Q16539	MAPK14	S819	R812W	812	Missense	distal	-7	no	11.591	10.851	EPSD	COSMIC	5.915	Down-regulation
CMGC_MAPK_p38_MAPK14_ST	Q14934	NFATC4	Q16539	MAPK14	S819	F826Y	826	Missense	distal	7	no	11.591	12.503	EPSD	COSMIC	5.915	Up-regulation
CMGC_MAPK_p38_MAPK14_ST	Q14934	NFATC4	Q16539	MAPK14	S819	P815S	815	Missense	distal	-4	no	11.591	11.503	EPSD	COSMIC	5.915	Down-regulation
CMGC_MAPK_p38_MAPK14_ST	Q9BR76	CORO1B	Q16539	MAPK14	S423	S424P	424	Missense	proximal	1	no	3.415	10.698	EPSD	COSMIC	5.915	Gain
CMGC_MAPK_p38_MAPK14_ST	Q9BR76	CORO1B	Q16539	MAPK14	T439	S441N	441	Missense	proximal	2	no	9.985	9.729	EPSD	COSMIC	5.915	Down-regulation
CMGC_MAPK_p38_MAPK14_ST	Q9BR76	CORO1B	Q16539	MAPK14	S441	S441N	441	Missense	central	0	yes	6.942	0.000	EPSD	COSMIC	5.915	Loss
CMGC_MAPK_p38_MAPK14_ST	O43524	FOXO3	Q16539	MAPK14	S7	A2V	2	Missense	distal	-5	no	10.158	10.650	PhosphoSitePlus;EPSD	COSMIC;CCLE	5.915	Up-regulation
CMGC_MAPK_p38_MAPK14_ST	O43524	FOXO3	Q16539	MAPK14	S7	A6S	6	Missense	proximal	-1	no	10.158	10.098	PhosphoSitePlus;EPSD	COSMIC	5.915	Down-regulation
CMGC_MAPK_p38_MAPK14_ST	O43524	FOXO3	Q16539	MAPK14	S12	A6S	6	Missense	distal	-6	no	13.512	14.055	EPSD;PhosphoSitePlus	COSMIC	5.915	Up-regulation
CMGC_MAPK_p38_MAPK14_ST	O43524	FOXO3	Q16539	MAPK14	T32	R29L	29	Missense	distal	-3	no	7.301	5.057	EPSD	COSMIC	5.915	Loss
CMGC_MAPK_p38_MAPK14_ST	O43524	FOXO3	Q16539	MAPK14	S43	E50D	50	Missense	distal	7	no	11.871	11.677	EPSD	COSMIC;CCLE	5.915	Down-regulation
CMGC_MAPK_p38_MAPK14_ST	O43524	FOXO3	Q16539	MAPK14	S55	E50D	50	Missense	distal	-5	no	6.289	7.163	EPSD	COSMIC;CCLE	5.915	Up-regulation
CMGC_MAPK_p38_MAPK14_ST	O43524	FOXO3	Q16539	MAPK14	S55	A53G	53	Missense	proximal	-2	no	6.289	6.013	EPSD	COSMIC	5.915	Down-regulation
CMGC_MAPK_p38_MAPK14_ST	O43524	FOXO3	Q16539	MAPK14	S294	P295L	295	Missense	proximal	1	no	10.128	2.077	EPSD;PhosphoSitePlus	COSMIC	5.915	Loss
CMGC_MAPK_p38_MAPK14_ST	O43524	FOXO3	Q16539	MAPK14	S325	S318C	318	Missense	distal	-7	no	12.190	11.629	EPSD	COSMIC	5.915	Down-regulation
CMGC_MAPK_p38_MAPK14_ST	O43524	FOXO3	Q16539	MAPK14	S325	R323C	323	Missense	proximal	-2	no	12.190	11.255	EPSD	COSMIC	5.915	Down-regulation
CMGC_MAPK_p38_MAPK14_ST	O43524	FOXO3	Q16539	MAPK14	S325	E332Q	332	Missense	distal	7	no	12.190	11.814	EPSD	COSMIC;CCLE	5.915	Down-regulation
CMGC_MAPK_p38_MAPK14_ST	O43524	FOXO3	Q16539	MAPK14	S325	R323H	323	Missense	proximal	-2	no	12.190	10.612	EPSD	COSMIC	5.915	Down-regulation
CMGC_MAPK_p38_MAPK14_ST	O43524	FOXO3	Q16539	MAPK14	S344	A341T	341	Missense	distal	-3	no	12.103	12.197	EPSD;PhosphoSitePlus	COSMIC	5.915	Up-regulation
CMGC_MAPK_p38_MAPK14_ST	O43524	FOXO3	Q16539	MAPK14	S355	P361L	361	Missense	distal	6	no	13.176	13.037	EPSD	COSMIC;GDSC;CCLE	5.915	Down-regulation
CMGC_MAPK_p38_MAPK14_ST	O43524	FOXO3	Q16539	MAPK14	S402	P397R	397	Missense	distal	-5	no	11.728	11.499	EPSD	COSMIC	5.915	Down-regulation
CMGC_MAPK_p38_MAPK14_ST	O43524	FOXO3	Q16539	MAPK14	S425	G424V	424	Missense	proximal	-1	no	11.529	11.531	EPSD;PhosphoSitePlus	COSMIC	5.915	Up-regulation
CMGC_MAPK_p38_MAPK14_ST	O43524	FOXO3	Q16539	MAPK14	S428	G424V	424	Missense	distal	-4	no	5.597	5.922	EPSD	COSMIC	5.915	Gain
CMGC_MAPK_p38_MAPK14_ST	P42566	EPS15	Q16539	MAPK14	S108	D105G	105	Missense	distal	-3	no	12.236	12.287	EPSD	COSMIC	5.915	Up-regulation
CMGC_MAPK_p38_MAPK14_ST	P42566	EPS15	Q16539	MAPK14	S140	D137Y	137	Missense	distal	-3	no	10.755	10.849	EPSD	COSMIC	5.915	Up-regulation
CMGC_MAPK_p38_MAPK14_ST	P42566	EPS15	Q16539	MAPK14	S140	L146R	146	Missense	distal	6	no	10.755	10.882	EPSD	COSMIC;CCLE	5.915	Up-regulation
CMGC_MAPK_p38_MAPK14_ST	P42566	EPS15	Q16539	MAPK14	S140	S140R	140	Missense	central	0	yes	10.755	0.000	EPSD	COSMIC;GDSC	5.915	Loss
CMGC_MAPK_p38_MAPK14_ST	P42566	EPS15	Q16539	MAPK14	S221	A223T	223	Missense	proximal	2	no	11.326	11.355	EPSD	COSMIC;GDSC;CCLE	5.915	Up-regulation
CMGC_MAPK_p38_MAPK14_ST	P42566	EPS15	Q16539	MAPK14	S324	S323L	323	Missense	proximal	-1	no	8.909	9.188	EPSD	COSMIC	5.915	Up-regulation
CMGC_MAPK_p38_MAPK14_ST	P42566	EPS15	Q16539	MAPK14	S324	P325A	325	Missense	proximal	1	no	8.909	2.591	EPSD	COSMIC	5.915	Loss
CMGC_MAPK_p38_MAPK14_ST	P42566	EPS15	Q16539	MAPK14	S330	S323L	323	Missense	distal	-7	no	7.637	7.357	EPSD	COSMIC	5.915	Down-regulation
CMGC_MAPK_p38_MAPK14_ST	P42566	EPS15	Q16539	MAPK14	S330	P325A	325	Missense	distal	-5	no	7.637	7.301	EPSD	COSMIC	5.915	Down-regulation
CMGC_MAPK_p38_MAPK14_ST	P42566	EPS15	Q16539	MAPK14	T337	N339S	339	Missense	proximal	2	no	5.779	6.035	EPSD	COSMIC	5.915	Gain
CMGC_MAPK_p38_MAPK14_ST	P42566	EPS15	Q16539	MAPK14	S428	L429P	429	Missense	proximal	1	no	2.291	10.342	EPSD	COSMIC;GDSC;CCLE	5.915	Gain
CMGC_MAPK_p38_MAPK14_ST	P42566	EPS15	Q16539	MAPK14	S514	W511L	511	Missense	distal	-3	no	6.914	7.027	EPSD	COSMIC	5.915	Up-regulation
CMGC_MAPK_p38_MAPK14_ST	P42566	EPS15	Q16539	MAPK14	S558	S551F	551	Missense	distal	-7	no	13.511	12.765	EPSD	COSMIC	5.915	Down-regulation
CMGC_MAPK_p38_MAPK14_ST	P42566	EPS15	Q16539	MAPK14	S558	Q556K	556	Missense	proximal	-2	no	13.511	13.235	EPSD	COSMIC	5.915	Down-regulation
CMGC_MAPK_p38_MAPK14_ST	P42566	EPS15	Q16539	MAPK14	S563	S569F	569	Missense	distal	6	no	10.221	9.864	EPSD	COSMIC	5.915	Down-regulation
CMGC_MAPK_p38_MAPK14_ST	P42566	EPS15	Q16539	MAPK14	S563	Q556K	556	Missense	distal	-7	no	10.221	10.580	EPSD	COSMIC	5.915	Up-regulation
CMGC_MAPK_p38_MAPK14_ST	P42566	EPS15	Q16539	MAPK14	S719	G721V	721	Missense	proximal	2	no	6.777	6.578	EPSD	COSMIC	5.915	Down-regulation
CMGC_MAPK_p38_MAPK14_ST	P42566	EPS15	Q16539	MAPK14	S719	N717S	717	Missense	proximal	-2	no	6.777	7.463	EPSD	COSMIC	5.915	Up-regulation
CMGC_MAPK_p38_MAPK14_ST	P42566	EPS15	Q16539	MAPK14	S719	A725S	725	Missense	distal	6	no	6.777	6.722	EPSD	COSMIC	5.915	Down-regulation
CMGC_MAPK_p38_MAPK14_ST	P42566	EPS15	Q16539	MAPK14	S741	N735S	735	Missense	distal	-6	no	6.487	6.910	EPSD	COSMIC;GDSC	5.915	Up-regulation
CMGC_MAPK_p38_MAPK14_ST	P42566	EPS15	Q16539	MAPK14	S741	R740C	740	Missense	proximal	-1	no	6.487	6.750	EPSD	COSMIC	5.915	Up-regulation
CMGC_MAPK_p38_MAPK14_ST	P42566	EPS15	Q16539	MAPK14	S744	R740C	740	Missense	distal	-4	no	7.117	7.567	EPSD	COSMIC	5.915	Up-regulation
CMGC_MAPK_p38_MAPK14_ST	P42566	EPS15	Q16539	MAPK14	S744	N749I	749	Missense	distal	5	no	7.117	6.360	EPSD	COSMIC	5.915	Down-regulation
CMGC_MAPK_p38_MAPK14_ST	P42566	EPS15	Q16539	MAPK14	S796	S790F	790	Missense	distal	-6	no	9.943	8.179	PhosphoSitePlus	COSMIC	5.915	Down-regulation
CMGC_MAPK_p38_MAPK14_ST	P42566	EPS15	Q16539	MAPK14	S814	G811D	811	Missense	distal	-3	no	14.302	14.251	EPSD	COSMIC	5.915	Down-regulation
CMGC_MAPK_p38_MAPK14_ST	P42566	EPS15	Q16539	MAPK14	S814	P808T	808	Missense	distal	-6	no	14.302	14.636	EPSD	COSMIC	5.915	Up-regulation
CMGC_MAPK_p38_MAPK14_ST	P42566	EPS15	Q16539	MAPK14	S814	G811C	811	Missense	distal	-3	no	14.302	13.557	EPSD	COSMIC	5.915	Down-regulation
CMGC_MAPK_p38_MAPK14_ST	P42566	EPS15	Q16539	MAPK14	S814	D819Y	819	Missense	distal	5	no	14.302	14.567	EPSD	COSMIC	5.915	Up-regulation
CMGC_MAPK_p38_MAPK14_ST	P42566	EPS15	Q16539	MAPK14	S847	N845S	845	Missense	proximal	-2	no	5.666	6.353	EPSD	COSMIC	5.915	Gain
CMGC_MAPK_p38_MAPK14_ST	P42566	EPS15	Q16539	MAPK14	S847	A844S	844	Missense	distal	-3	no	5.666	6.079	EPSD	COSMIC	5.915	Gain
CMGC_MAPK_p38_MAPK14_ST	O60381	HBP1	Q16539	MAPK14	S135	R133T	133	Missense	proximal	-2	no	10.736	10.705	EPSD	COSMIC;GDSC	5.915	Down-regulation
CMGC_MAPK_p38_MAPK14_ST	O60381	HBP1	Q16539	MAPK14	S402	G401D	401	Missense	proximal	-1	no	9.658	9.702	PhosphoSitePlus	COSMIC	5.915	Up-regulation
CMGC_MAPK_p38_MAPK14_ST	O60381	HBP1	Q16539	MAPK14	S405	G401D	401	Missense	distal	-4	no	5.663	6.158	EPSD	COSMIC	5.915	Gain
CMGC_MAPK_p38_MAPK14_ST	Q8IW41	MAPKAPK5	Q16539	MAPK14	T182	Q184E	184	Missense	proximal	2	no	9.718	10.255	PhosphoSitePlus	COSMIC	5.915	Up-regulation
CMGC_MAPK_p38_MAPK14_ST	Q8IW41	MAPKAPK5	Q16539	MAPK14	T182	T186I	186	Missense	distal	4	no	9.718	9.191	PhosphoSitePlus	COSMIC	5.915	Down-regulation
CMGC_MAPK_p38_MAPK14_ST	Q8IW41	MAPKAPK5	Q16539	MAPK14	T186	Q184E	184	Missense	proximal	-2	no	12.505	13.260	EPSD	COSMIC	5.915	Up-regulation
CMGC_MAPK_p38_MAPK14_ST	Q8IW41	MAPKAPK5	Q16539	MAPK14	T186	T186I	186	Missense	central	0	yes	12.505	0.000	EPSD	COSMIC	5.915	Loss
CMGC_MAPK_p38_MAPK14_ST	P17302	GJA1	Q16539	MAPK14	S255	P256T	256	Missense	proximal	1	no	9.570	2.117	EPSD	COSMIC	5.915	Loss
CMGC_MAPK_p38_MAPK14_ST	P17302	GJA1	Q16539	MAPK14	S255	A253V	253	Missense	proximal	-2	no	9.570	9.155	EPSD	COSMIC	5.915	Down-regulation
CMGC_MAPK_p38_MAPK14_ST	P17302	GJA1	Q16539	MAPK14	S255	D259Y	259	Missense	distal	4	no	9.570	9.693	EPSD	COSMIC	5.915	Up-regulation
CMGC_MAPK_p38_MAPK14_ST	P17302	GJA1	Q16539	MAPK14	S273	S279L	279	Missense	distal	6	no	9.914	9.787	EPSD	COSMIC	5.915	Down-regulation
CMGC_MAPK_p38_MAPK14_ST	P17302	GJA1	Q16539	MAPK14	T275	S279L	279	Missense	distal	4	no	7.352	6.273	EPSD	COSMIC	5.915	Down-regulation
CMGC_MAPK_p38_MAPK14_ST	P17302	GJA1	Q16539	MAPK14	S279	S279L	279	Missense	central	0	yes	14.969	0.000	PhosphoSitePlus;EPSD	COSMIC	5.915	Loss
CMGC_MAPK_p38_MAPK14_ST	P17302	GJA1	Q16539	MAPK14	S282	S279L	279	Missense	distal	-3	no	13.285	11.553	EPSD;PhosphoSitePlus	COSMIC	5.915	Down-regulation
CMGC_MAPK_p38_MAPK14_ST	P17302	GJA1	Q16539	MAPK14	S364	P363L	363	Missense	proximal	-1	no	6.602	6.787	EPSD	COSMIC	5.915	Up-regulation
CMGC_MAPK_p38_MAPK14_ST	P17302	GJA1	Q16539	MAPK14	S368	P363L	363	Missense	distal	-5	no	7.255	7.536	EPSD	COSMIC	5.915	Up-regulation
CMGC_MAPK_p38_MAPK14_ST	P17302	GJA1	Q16539	MAPK14	S368	R370S	370	Missense	proximal	2	no	7.255	7.400	EPSD	COSMIC	5.915	Up-regulation
CMGC_MAPK_p38_MAPK14_ST	P17302	GJA1	Q16539	MAPK14	S369	R370S	370	Missense	proximal	1	no	5.536	6.188	EPSD	COSMIC	5.915	Gain
CMGC_MAPK_p38_MAPK14_ST	P17302	GJA1	Q16539	MAPK14	S372	R370S	370	Missense	proximal	-2	no	7.971	8.171	EPSD	COSMIC	5.915	Up-regulation
CMGC_MAPK_p38_MAPK14_ST	O43464	HTRA2	Q16539	MAPK14	T54	V50G	50	Missense	distal	-4	no	9.510	9.185	EPSD	COSMIC	5.915	Down-regulation
CMGC_MAPK_p38_MAPK14_ST	O43464	HTRA2	Q16539	MAPK14	T54	W58C	58	Missense	distal	4	no	9.510	10.350	EPSD	COSMIC	5.915	Up-regulation
CMGC_MAPK_p38_MAPK14_ST	O43464	HTRA2	Q16539	MAPK14	S96	T101N	101	Missense	distal	5	no	7.175	7.006	EPSD	COSMIC	5.915	Down-regulation
CMGC_MAPK_p38_MAPK14_ST	O43464	HTRA2	Q16539	MAPK14	S142	A141S	141	Missense	proximal	-1	no	11.644	11.584	PhosphoSitePlus	COSMIC	5.915	Down-regulation
CMGC_MAPK_p38_MAPK14_ST	O43464	HTRA2	Q16539	MAPK14	S142	S137R	137	Missense	distal	-5	no	11.644	11.862	PhosphoSitePlus	COSMIC	5.915	Up-regulation
CMGC_MAPK_p38_MAPK14_ST	O43464	HTRA2	Q16539	MAPK14	S142	P139Q	139	Missense	distal	-3	no	11.644	11.141	PhosphoSitePlus	COSMIC	5.915	Down-regulation
CMGC_MAPK_p38_MAPK14_ST	O43464	HTRA2	Q16539	MAPK14	S330	K324R	324	Missense	distal	-6	no	5.554	6.033	EPSD	COSMIC	5.915	Gain
CMGC_MAPK_p38_MAPK14_ST	O43464	HTRA2	Q16539	MAPK14	S400	G399S	399	Missense	proximal	-1	no	8.322	8.109	EPSD	COSMIC	5.915	Down-regulation
CMGC_MAPK_p38_MAPK14_ST	O43464	HTRA2	Q16539	MAPK14	T453	T457K	457	Missense	distal	4	no	12.371	12.666	EPSD	COSMIC	5.915	Up-regulation
CMGC_MAPK_p38_MAPK14_ST	O43464	HTRA2	Q16539	MAPK14	T453	Y451C	451	Missense	proximal	-2	no	12.371	11.233	EPSD	COSMIC	5.915	Down-regulation
CMGC_MAPK_p38_MAPK14_ST	Q92993	KAT5	Q16539	MAPK14	T77	P78T	78	Missense	proximal	1	no	7.401	-0.053	EPSD	COSMIC	5.915	Loss
CMGC_MAPK_p38_MAPK14_ST	Q92993	KAT5	Q16539	MAPK14	T77	G82E	82	Missense	distal	5	no	7.401	7.618	EPSD	COSMIC	5.915	Up-regulation
CMGC_MAPK_p38_MAPK14_ST	Q92993	KAT5	Q16539	MAPK14	S155	R149Q	149	Missense	distal	-6	no	12.906	12.236	EPSD	COSMIC	5.915	Down-regulation
CMGC_MAPK_p38_MAPK14_ST	Q92993	KAT5	Q16539	MAPK14	S155	V160M	160	Missense	distal	5	no	12.906	13.084	EPSD	COSMIC	5.915	Up-regulation
CMGC_MAPK_p38_MAPK14_ST	Q92993	KAT5	Q16539	MAPK14	S155	S155L	155	Missense	central	0	yes	12.906	0.000	EPSD	COSMIC	5.915	Loss
CMGC_MAPK_p38_MAPK14_ST	Q92993	KAT5	Q16539	MAPK14	S155	R149L	149	Missense	distal	-6	no	12.906	11.793	EPSD	COSMIC	5.915	Down-regulation
CMGC_MAPK_p38_MAPK14_ST	Q92993	KAT5	Q16539	MAPK14	S155	R149W	149	Missense	distal	-6	no	12.906	11.589	EPSD	COSMIC	5.915	Down-regulation
CMGC_MAPK_p38_MAPK14_ST	Q92993	KAT5	Q16539	MAPK14	S155	V153M	153	Missense	proximal	-2	no	12.906	13.172	EPSD	COSMIC	5.915	Up-regulation
CMGC_MAPK_p38_MAPK14_ST	Q92993	KAT5	Q16539	MAPK14	T158	V160M	160	Missense	proximal	2	no	12.148	12.322	EPSD;PhosphoSitePlus	COSMIC	5.915	Up-regulation
CMGC_MAPK_p38_MAPK14_ST	Q92993	KAT5	Q16539	MAPK14	T158	S155L	155	Missense	distal	-3	no	12.148	10.417	EPSD;PhosphoSitePlus	COSMIC	5.915	Down-regulation
CMGC_MAPK_p38_MAPK14_ST	Q92993	KAT5	Q16539	MAPK14	T158	V153M	153	Missense	distal	-5	no	12.148	11.697	EPSD;PhosphoSitePlus	COSMIC	5.915	Down-regulation
CMGC_MAPK_p38_MAPK14_ST	Q92993	KAT5	Q16539	MAPK14	S208	R211H	211	Missense	distal	3	no	5.847	5.918	EPSD	COSMIC	5.915	Gain
CMGC_MAPK_p38_MAPK14_ST	P41235	HNF4A	Q16539	MAPK14	S167	Q164H	164	Missense	distal	-3	no	7.662	7.687	PhosphoSitePlus	COSMIC	5.915	Up-regulation
CMGC_MAPK_p38_MAPK14_ST	P41235	HNF4A	Q16539	MAPK14	S167	G171R	171	Missense	distal	4	no	7.662	7.177	PhosphoSitePlus	COSMIC	5.915	Down-regulation
CMGC_MAPK_p38_MAPK14_ST	P41235	HNF4A	Q16539	MAPK14	S167	P168T	168	Missense	proximal	1	no	7.662	0.208	PhosphoSitePlus	COSMIC	5.915	Loss
CMGC_MAPK_p38_MAPK14_ST	P41235	HNF4A	Q16539	MAPK14	S167	S170F	170	Missense	distal	3	no	7.662	7.770	PhosphoSitePlus	COSMIC	5.915	Up-regulation
CMGC_MAPK_p38_MAPK14_ST	P41235	HNF4A	Q16539	MAPK14	S167	R163G	163	Missense	distal	-4	no	7.662	7.649	PhosphoSitePlus	COSMIC	5.915	Down-regulation
CMGC_MAPK_p38_MAPK14_ST	P41235	HNF4A	Q16539	MAPK14	S167	R163Q	163	Missense	distal	-4	no	7.662	8.030	PhosphoSitePlus	COSMIC	5.915	Up-regulation
CMGC_MAPK_p38_MAPK14_ST	P41235	HNF4A	Q16539	MAPK14	S167	G174D	174	Missense	distal	7	no	7.662	7.828	PhosphoSitePlus	COSMIC	5.915	Up-regulation
CMGC_MAPK_p38_MAPK14_ST	P41235	HNF4A	Q16539	MAPK14	S313	L319P	319	Missense	distal	6	no	7.604	7.743	EPSD	COSMIC	5.915	Up-regulation
CMGC_MAPK_p38_MAPK14_ST	P41235	HNF4A	Q16539	MAPK14	S318	L319P	319	Missense	proximal	1	no	1.269	9.320	EPSD	COSMIC	5.915	Gain
CMGC_MAPK_p38_MAPK14_ST	P41235	HNF4A	Q16539	MAPK14	S378	M373V	373	Missense	distal	-5	no	11.760	12.211	EPSD	COSMIC	5.915	Up-regulation
CMGC_MAPK_p38_MAPK14_ST	P41235	HNF4A	Q16539	MAPK14	S378	H384Y	384	Missense	distal	6	no	11.760	11.886	EPSD	COSMIC	5.915	Up-regulation
CMGC_MAPK_p38_MAPK14_ST	P41235	HNF4A	Q16539	MAPK14	S378	E372K	372	Missense	distal	-6	no	11.760	11.346	EPSD	COSMIC	5.915	Down-regulation
CMGC_MAPK_p38_MAPK14_ST	P41235	HNF4A	Q16539	MAPK14	T429	A427D	427	Missense	proximal	-2	no	8.288	7.261	EPSD	COSMIC	5.915	Down-regulation
CMGC_MAPK_p38_MAPK14_ST	P41235	HNF4A	Q16539	MAPK14	T429	P433T	433	Missense	distal	4	no	8.288	8.466	EPSD	COSMIC	5.915	Up-regulation
CMGC_MAPK_p38_MAPK14_ST	P41235	HNF4A	Q16539	MAPK14	T429	G425E	425	Missense	distal	-4	no	8.288	7.991	EPSD	COSMIC	5.915	Down-regulation
CMGC_MAPK_p38_MAPK14_ST	P41235	HNF4A	Q16539	MAPK14	T429	P430S	430	Missense	proximal	1	no	8.288	1.004	EPSD	COSMIC	5.915	Loss
CMGC_MAPK_p38_MAPK14_ST	P41235	HNF4A	Q16539	MAPK14	T429	A427T	427	Missense	proximal	-2	no	8.288	8.231	EPSD	COSMIC	5.915	Down-regulation
CMGC_MAPK_p38_MAPK14_ST	P41235	HNF4A	Q16539	MAPK14	T429	T429I	429	Missense	central	0	yes	8.288	0.000	EPSD	COSMIC	5.915	Loss
CMGC_MAPK_p38_MAPK14_ST	P41235	HNF4A	Q16539	MAPK14	T429	P423T	423	Missense	distal	-6	no	8.288	8.622	EPSD	COSMIC	5.915	Up-regulation
CMGC_MAPK_p38_MAPK14_ST	P41235	HNF4A	Q16539	MAPK14	T432	A427D	427	Missense	distal	-5	no	10.565	11.077	EPSD	COSMIC	5.915	Up-regulation
CMGC_MAPK_p38_MAPK14_ST	P41235	HNF4A	Q16539	MAPK14	T432	P433T	433	Missense	proximal	1	no	10.565	3.112	EPSD	COSMIC	5.915	Loss
CMGC_MAPK_p38_MAPK14_ST	P41235	HNF4A	Q16539	MAPK14	T432	G425E	425	Missense	distal	-7	no	10.565	10.783	EPSD	COSMIC	5.915	Up-regulation
CMGC_MAPK_p38_MAPK14_ST	P41235	HNF4A	Q16539	MAPK14	T432	P430S	430	Missense	proximal	-2	no	10.565	10.077	EPSD	COSMIC	5.915	Down-regulation
CMGC_MAPK_p38_MAPK14_ST	P41235	HNF4A	Q16539	MAPK14	T432	P437S	437	Missense	distal	5	no	10.565	11.016	EPSD	COSMIC	5.915	Up-regulation
CMGC_MAPK_p38_MAPK14_ST	P41235	HNF4A	Q16539	MAPK14	T432	A427T	427	Missense	distal	-5	no	10.565	10.895	EPSD	COSMIC	5.915	Up-regulation
CMGC_MAPK_p38_MAPK14_ST	P41235	HNF4A	Q16539	MAPK14	T432	T429I	429	Missense	distal	-3	no	10.565	8.811	EPSD	COSMIC	5.915	Down-regulation
CMGC_MAPK_p38_MAPK14_ST	P41235	HNF4A	Q16539	MAPK14	T432	G439C	439	Missense	distal	7	no	10.565	10.144	EPSD	COSMIC	5.915	Down-regulation
CMGC_MAPK_p38_MAPK14_ST	P41235	HNF4A	Q16539	MAPK14	T432	P437T	437	Missense	distal	5	no	10.565	10.850	EPSD	COSMIC	5.915	Up-regulation
CMGC_MAPK_p38_MAPK14_ST	P41235	HNF4A	Q16539	MAPK14	S436	P433T	433	Missense	distal	-3	no	10.226	10.672	EPSD	COSMIC	5.915	Up-regulation
CMGC_MAPK_p38_MAPK14_ST	P41235	HNF4A	Q16539	MAPK14	S436	P430S	430	Missense	distal	-6	no	10.226	10.833	EPSD	COSMIC	5.915	Up-regulation
CMGC_MAPK_p38_MAPK14_ST	P41235	HNF4A	Q16539	MAPK14	S436	P437S	437	Missense	proximal	1	no	10.226	2.942	EPSD	COSMIC	5.915	Loss
CMGC_MAPK_p38_MAPK14_ST	P41235	HNF4A	Q16539	MAPK14	S436	T429I	429	Missense	distal	-7	no	10.226	9.875	EPSD	COSMIC	5.915	Down-regulation
CMGC_MAPK_p38_MAPK14_ST	P41235	HNF4A	Q16539	MAPK14	S436	G439C	439	Missense	distal	3	no	10.226	10.269	EPSD	COSMIC	5.915	Up-regulation
CMGC_MAPK_p38_MAPK14_ST	P41235	HNF4A	Q16539	MAPK14	S436	P437T	437	Missense	proximal	1	no	10.226	2.773	EPSD	COSMIC	5.915	Loss
CMGC_MAPK_p38_MAPK14_ST	P41235	HNF4A	Q16539	MAPK14	S461	L460V	460	Missense	proximal	-1	no	6.182	6.119	EPSD	COSMIC	5.915	Down-regulation
CMGC_MAPK_p38_MAPK14_ST	P41235	HNF4A	Q16539	MAPK14	S461	P459T	459	Missense	proximal	-2	no	6.182	5.462	EPSD	COSMIC	5.915	Loss
CMGC_MAPK_p38_MAPK14_ST	P41235	HNF4A	Q16539	MAPK14	S461	P459S	459	Missense	proximal	-2	no	6.182	5.693	EPSD	COSMIC	5.915	Loss
CMGC_MAPK_p38_MAPK14_ST	P41235	HNF4A	Q16539	MAPK14	S461	A454T	454	Missense	distal	-7	no	6.182	5.999	EPSD	COSMIC	5.915	Down-regulation
CMGC_MAPK_p38_MAPK14_ST	P05787	KRT8	Q16539	MAPK14	S27	S31A	31	Missense	distal	4	no	5.963	5.657	EPSD	COSMIC	5.915	Loss
CMGC_MAPK_p38_MAPK14_ST	P05787	KRT8	Q16539	MAPK14	S27	S31Y	31	Missense	distal	4	no	5.963	4.916	EPSD	COSMIC	5.915	Loss
CMGC_MAPK_p38_MAPK14_ST	P05787	KRT8	Q16539	MAPK14	S34	S35F	35	Missense	proximal	1	no	5.512	6.792	EPSD	COSMIC	5.915	Gain
CMGC_MAPK_p38_MAPK14_ST	P05787	KRT8	Q16539	MAPK14	S35	S31A	31	Missense	distal	-4	no	6.190	6.230	EPSD	COSMIC	5.915	Up-regulation
CMGC_MAPK_p38_MAPK14_ST	P05787	KRT8	Q16539	MAPK14	S35	S36L	36	Missense	proximal	1	no	6.190	5.423	EPSD	COSMIC	5.915	Loss
CMGC_MAPK_p38_MAPK14_ST	P05787	KRT8	Q16539	MAPK14	S35	S31Y	31	Missense	distal	-4	no	6.190	6.186	EPSD	COSMIC	5.915	Down-regulation
CMGC_MAPK_p38_MAPK14_ST	P05787	KRT8	Q16539	MAPK14	S35	S35F	35	Missense	central	0	yes	6.190	0.000	EPSD	COSMIC	5.915	Loss
CMGC_MAPK_p38_MAPK14_ST	P05787	KRT8	Q16539	MAPK14	S37	S43F	43	Missense	distal	6	no	7.166	6.809	EPSD	COSMIC	5.915	Down-regulation
CMGC_MAPK_p38_MAPK14_ST	P05787	KRT8	Q16539	MAPK14	S37	S31A	31	Missense	distal	-6	no	7.166	6.623	EPSD	COSMIC	5.915	Down-regulation
CMGC_MAPK_p38_MAPK14_ST	P05787	KRT8	Q16539	MAPK14	S37	S36L	36	Missense	proximal	-1	no	7.166	7.444	EPSD	COSMIC	5.915	Up-regulation
CMGC_MAPK_p38_MAPK14_ST	P05787	KRT8	Q16539	MAPK14	S37	S43I	43	Missense	distal	6	no	7.166	6.955	EPSD	COSMIC	5.915	Down-regulation
CMGC_MAPK_p38_MAPK14_ST	P05787	KRT8	Q16539	MAPK14	S37	S43R	43	Missense	distal	6	no	7.166	7.165	EPSD	COSMIC	5.915	Down-regulation
CMGC_MAPK_p38_MAPK14_ST	P05787	KRT8	Q16539	MAPK14	S37	S31Y	31	Missense	distal	-6	no	7.166	6.400	EPSD	COSMIC	5.915	Down-regulation
CMGC_MAPK_p38_MAPK14_ST	P05787	KRT8	Q16539	MAPK14	S37	S35F	35	Missense	proximal	-2	no	7.166	6.442	EPSD	COSMIC	5.915	Down-regulation
CMGC_MAPK_p38_MAPK14_ST	P05787	KRT8	Q16539	MAPK14	S43	S43F	43	Missense	central	0	yes	6.445	0.000	EPSD	COSMIC	5.915	Loss
CMGC_MAPK_p38_MAPK14_ST	P05787	KRT8	Q16539	MAPK14	S43	S36L	36	Missense	distal	-7	no	6.445	6.165	EPSD	COSMIC	5.915	Down-regulation
CMGC_MAPK_p38_MAPK14_ST	P05787	KRT8	Q16539	MAPK14	S43	S43I	43	Missense	central	0	yes	6.445	0.000	EPSD	COSMIC	5.915	Loss
CMGC_MAPK_p38_MAPK14_ST	P05787	KRT8	Q16539	MAPK14	S43	S43R	43	Missense	central	0	yes	6.445	0.000	EPSD	COSMIC	5.915	Loss
CMGC_MAPK_p38_MAPK14_ST	P05787	KRT8	Q16539	MAPK14	S74	S71R	71	Missense	distal	-3	no	11.739	12.251	PhosphoSitePlus	COSMIC	5.915	Up-regulation
CMGC_MAPK_p38_MAPK14_ST	P05787	KRT8	Q16539	MAPK14	S74	S71I	71	Missense	distal	-3	no	11.739	9.667	PhosphoSitePlus	COSMIC	5.915	Down-regulation
CMGC_MAPK_p38_MAPK14_ST	P05787	KRT8	Q16539	MAPK14	S74	V77G	77	Missense	distal	3	no	11.739	11.738	PhosphoSitePlus	COSMIC	5.915	Down-regulation
CMGC_MAPK_p38_MAPK14_ST	P05787	KRT8	Q16539	MAPK14	T305	R301C	301	Missense	distal	-4	no	5.836	6.286	EPSD	COSMIC	5.915	Gain
CMGC_MAPK_p38_MAPK14_ST	P05787	KRT8	Q16539	MAPK14	T305	R301Q	301	Missense	distal	-4	no	5.836	6.204	EPSD	COSMIC	5.915	Gain
CMGC_MAPK_p38_MAPK14_ST	P05787	KRT8	Q16539	MAPK14	S315	R316W	316	Missense	proximal	1	no	5.095	7.061	EPSD	COSMIC	5.915	Gain
CMGC_MAPK_p38_MAPK14_ST	P05787	KRT8	Q16539	MAPK14	S432	G434S	434	Missense	proximal	2	no	8.643	8.872	EPSD	COSMIC	5.915	Up-regulation
CMGC_MAPK_p38_MAPK14_ST	P05787	KRT8	Q16539	MAPK14	S451	S449F	449	Missense	proximal	-2	no	7.278	6.554	EPSD	COSMIC	5.915	Down-regulation
CMGC_MAPK_p38_MAPK14_ST	P05787	KRT8	Q16539	MAPK14	S451	S449A	449	Missense	proximal	-2	no	7.278	7.104	EPSD	COSMIC	5.915	Down-regulation
CMGC_MAPK_p38_MAPK14_ST	P05787	KRT8	Q16539	MAPK14	S451	S458F	458	Missense	distal	7	no	7.278	6.408	EPSD	COSMIC	5.915	Down-regulation
CMGC_MAPK_p38_MAPK14_ST	P05787	KRT8	Q16539	MAPK14	S451	S458T	458	Missense	distal	7	no	7.278	6.957	EPSD	COSMIC	5.915	Down-regulation
CMGC_MAPK_p38_MAPK14_ST	P05787	KRT8	Q16539	MAPK14	S451	R454G	454	Missense	distal	3	no	7.278	7.292	EPSD	COSMIC	5.915	Up-regulation
CMGC_MAPK_p38_MAPK14_ST	P05787	KRT8	Q16539	MAPK14	S451	A447V	447	Missense	distal	-4	no	7.278	7.560	EPSD	COSMIC	5.915	Up-regulation
CMGC_MAPK_p38_MAPK14_ST	P11362	FGFR1	Q16539	MAPK14	T454	S451F	451	Missense	distal	-3	no	14.298	11.591	EPSD	COSMIC	5.915	Down-regulation
CMGC_MAPK_p38_MAPK14_ST	P11362	FGFR1	Q16539	MAPK14	T454	R448Q	448	Missense	distal	-6	no	14.298	13.629	EPSD	COSMIC	5.915	Down-regulation
CMGC_MAPK_p38_MAPK14_ST	P11362	FGFR1	Q16539	MAPK14	T454	S451C	451	Missense	distal	-3	no	14.298	12.615	EPSD	COSMIC	5.915	Down-regulation
CMGC_MAPK_p38_MAPK14_ST	P11362	FGFR1	Q16539	MAPK14	T454	G459R	459	Missense	distal	5	no	14.298	14.244	EPSD	COSMIC	5.915	Down-regulation
CMGC_MAPK_p38_MAPK14_ST	P11362	FGFR1	Q16539	MAPK14	T454	T454N	454	Missense	central	0	yes	14.298	0.000	EPSD	COSMIC	5.915	Loss
CMGC_MAPK_p38_MAPK14_ST	P11362	FGFR1	Q16539	MAPK14	T454	S447P	447	Missense	distal	-7	no	14.298	14.211	EPSD	COSMIC	5.915	Down-regulation
CMGC_MAPK_p38_MAPK14_ST	P11362	FGFR1	Q16539	MAPK14	T454	M456I	456	Missense	proximal	2	no	14.298	14.073	EPSD	COSMIC;GDSC	5.915	Down-regulation
CMGC_MAPK_p38_MAPK14_ST	P11362	FGFR1	Q16539	MAPK14	T454	M456V	456	Missense	proximal	2	no	14.298	14.125	EPSD	COSMIC	5.915	Down-regulation
CMGC_MAPK_p38_MAPK14_ST	P11362	FGFR1	Q16539	MAPK14	T454	S447L	447	Missense	distal	-7	no	14.298	14.018	EPSD	COSMIC	5.915	Down-regulation
CMGC_MAPK_p38_MAPK14_ST	P11362	FGFR1	Q16539	MAPK14	T454	R448L	448	Missense	distal	-6	no	14.298	13.185	EPSD	COSMIC	5.915	Down-regulation
CMGC_MAPK_p38_MAPK14_ST	P11362	FGFR1	Q16539	MAPK14	T454	L457R	457	Missense	distal	3	no	14.298	14.252	EPSD	COSMIC	5.915	Down-regulation
CMGC_MAPK_p38_MAPK14_ST	P11362	FGFR1	Q16539	MAPK14	S777	S779C	779	Missense	proximal	2	no	11.320	10.907	PhosphoSitePlus	COSMIC	5.915	Down-regulation
CMGC_MAPK_p38_MAPK14_ST	P11362	FGFR1	Q16539	MAPK14	S777	R784Q	784	Missense	distal	7	no	11.320	11.126	PhosphoSitePlus	COSMIC	5.915	Down-regulation
CMGC_MAPK_p38_MAPK14_ST	P11362	FGFR1	Q16539	MAPK14	S777	R784W	784	Missense	distal	7	no	11.320	10.631	PhosphoSitePlus	COSMIC	5.915	Down-regulation
CMGC_MAPK_p38_MAPK14_ST	P11362	FGFR1	Q16539	MAPK14	S777	P772S	772	Missense	distal	-5	no	11.320	10.872	PhosphoSitePlus	COSMIC;GDSC	5.915	Down-regulation
CMGC_MAPK_p38_MAPK14_ST	P11362	FGFR1	Q16539	MAPK14	S777	D782N	782	Missense	distal	5	no	11.320	11.529	PhosphoSitePlus	COSMIC	5.915	Up-regulation
CMGC_MAPK_p38_MAPK14_ST	P11362	FGFR1	Q16539	MAPK14	S777	P772H	772	Missense	distal	-5	no	11.320	11.634	PhosphoSitePlus	COSMIC	5.915	Up-regulation
CMGC_MAPK_p38_MAPK14_ST	P11362	FGFR1	Q16539	MAPK14	S785	S779C	779	Missense	distal	-6	no	7.863	6.571	EPSD	COSMIC	5.915	Down-regulation
CMGC_MAPK_p38_MAPK14_ST	P11362	FGFR1	Q16539	MAPK14	S785	G791E	791	Missense	distal	6	no	7.863	7.822	EPSD	COSMIC	5.915	Down-regulation
CMGC_MAPK_p38_MAPK14_ST	P11362	FGFR1	Q16539	MAPK14	S785	R784Q	784	Missense	proximal	-1	no	7.863	7.952	EPSD	COSMIC	5.915	Up-regulation
CMGC_MAPK_p38_MAPK14_ST	P11362	FGFR1	Q16539	MAPK14	S785	R784W	784	Missense	proximal	-1	no	7.863	8.151	EPSD	COSMIC	5.915	Up-regulation
CMGC_MAPK_p38_MAPK14_ST	P11362	FGFR1	Q16539	MAPK14	S785	S789C	789	Missense	distal	4	no	7.863	6.712	EPSD	COSMIC	5.915	Down-regulation
CMGC_MAPK_p38_MAPK14_ST	P11362	FGFR1	Q16539	MAPK14	S785	D782N	782	Missense	distal	-3	no	7.863	7.705	EPSD	COSMIC	5.915	Down-regulation
CMGC_MAPK_p38_MAPK14_ST	P11362	FGFR1	Q16539	MAPK14	S785	S790P	790	Missense	distal	5	no	7.863	7.413	EPSD	COSMIC	5.915	Down-regulation
CMGC_MAPK_p38_MAPK14_ST	P11362	FGFR1	Q16539	MAPK14	S789	S790P	790	Missense	proximal	1	no	2.248	9.532	EPSD	COSMIC	5.915	Gain
CMGC_MAPK_p38_MAPK14_ST	O15151	MDM4	Q16539	MAPK14	S20	S20C	20	Missense	central	0	yes	7.768	0.000	EPSD	COSMIC	5.915	Loss
CMGC_MAPK_p38_MAPK14_ST	O15151	MDM4	Q16539	MAPK14	S20	S15R	15	Missense	distal	-5	no	7.768	7.986	EPSD	COSMIC	5.915	Up-regulation
CMGC_MAPK_p38_MAPK14_ST	O15151	MDM4	Q16539	MAPK14	S20	I24M	24	Missense	distal	4	no	7.768	8.233	EPSD	COSMIC	5.915	Up-regulation
CMGC_MAPK_p38_MAPK14_ST	O15151	MDM4	Q16539	MAPK14	S20	P21S	21	Missense	proximal	1	no	7.768	0.484	EPSD	COSMIC	5.915	Loss
CMGC_MAPK_p38_MAPK14_ST	O15151	MDM4	Q16539	MAPK14	S20	D14H	14	Missense	distal	-6	no	7.768	7.447	EPSD	COSMIC	5.915	Down-regulation
CMGC_MAPK_p38_MAPK14_ST	O15151	MDM4	Q16539	MAPK14	T263	G268E	268	Missense	distal	5	no	6.163	6.380	EPSD	COSMIC	5.915	Up-regulation
CMGC_MAPK_p38_MAPK14_ST	O15151	MDM4	Q16539	MAPK14	T263	V267A	267	Missense	distal	4	no	6.163	6.597	EPSD	COSMIC;GDSC;CCLE	5.915	Up-regulation
CMGC_MAPK_p38_MAPK14_ST	O15151	MDM4	Q16539	MAPK14	T263	D259N	259	Missense	distal	-4	no	6.163	5.743	EPSD	COSMIC	5.915	Loss
CMGC_MAPK_p38_MAPK14_ST	O15151	MDM4	Q16539	MAPK14	S314	E308D	308	Missense	distal	-6	no	11.158	10.580	PhosphoSitePlus	COSMIC	5.915	Down-regulation
CMGC_MAPK_p38_MAPK14_ST	O15151	MDM4	Q16539	MAPK14	S314	K310N	310	Missense	distal	-4	no	11.158	11.305	PhosphoSitePlus	COSMIC	5.915	Up-regulation
CMGC_MAPK_p38_MAPK14_ST	O95644	NFATC1	Q16539	MAPK14	S117	P113S	113	Missense	distal	-4	no	13.323	13.236	EPSD	COSMIC	5.915	Down-regulation
CMGC_MAPK_p38_MAPK14_ST	O95644	NFATC1	Q16539	MAPK14	S117	A112T	112	Missense	distal	-5	no	13.323	13.652	EPSD	COSMIC	5.915	Up-regulation
CMGC_MAPK_p38_MAPK14_ST	O95644	NFATC1	Q16539	MAPK14	S117	P118L	118	Missense	proximal	1	no	13.323	5.272	EPSD	COSMIC	5.915	Loss
CMGC_MAPK_p38_MAPK14_ST	O95644	NFATC1	Q16539	MAPK14	S151	K149R	149	Missense	proximal	-2	no	10.719	11.322	EPSD	COSMIC	5.915	Up-regulation
CMGC_MAPK_p38_MAPK14_ST	O95644	NFATC1	Q16539	MAPK14	S151	S153F	153	Missense	proximal	2	no	10.719	10.053	EPSD	COSMIC	5.915	Down-regulation
CMGC_MAPK_p38_MAPK14_ST	O95644	NFATC1	Q16539	MAPK14	T154	K149R	149	Missense	distal	-5	no	7.215	7.350	EPSD	COSMIC	5.915	Up-regulation
CMGC_MAPK_p38_MAPK14_ST	O95644	NFATC1	Q16539	MAPK14	T154	S153F	153	Missense	proximal	-1	no	7.215	7.457	EPSD	COSMIC	5.915	Up-regulation
CMGC_MAPK_p38_MAPK14_ST	O95644	NFATC1	Q16539	MAPK14	S172	D167H	167	Missense	distal	-5	no	13.182	13.321	PhosphoSitePlus	COSMIC	5.915	Up-regulation
CMGC_MAPK_p38_MAPK14_ST	O95644	NFATC1	Q16539	MAPK14	S175	R180Q	180	Missense	distal	5	no	6.910	6.561	EPSD	COSMIC	5.915	Down-regulation
CMGC_MAPK_p38_MAPK14_ST	O95644	NFATC1	Q16539	MAPK14	S184	R180Q	180	Missense	distal	-4	no	6.285	6.654	EPSD	COSMIC	5.915	Up-regulation
CMGC_MAPK_p38_MAPK14_ST	O95644	NFATC1	Q16539	MAPK14	S184	E190D	190	Missense	distal	6	no	6.285	6.185	EPSD	COSMIC	5.915	Down-regulation
CMGC_MAPK_p38_MAPK14_ST	O95644	NFATC1	Q16539	MAPK14	S211	Q206H	206	Missense	distal	-5	no	10.863	11.449	EPSD	COSMIC	5.915	Up-regulation
CMGC_MAPK_p38_MAPK14_ST	O95644	NFATC1	Q16539	MAPK14	S211	T214I	214	Missense	distal	3	no	10.863	10.946	EPSD	COSMIC	5.915	Up-regulation
CMGC_MAPK_p38_MAPK14_ST	O95644	NFATC1	Q16539	MAPK14	S233	S237P	237	Missense	distal	4	no	10.753	10.314	EPSD	COSMIC	5.915	Down-regulation
CMGC_MAPK_p38_MAPK14_ST	O95644	NFATC1	Q16539	MAPK14	S233	C228Y	228	Missense	distal	-5	no	10.753	10.501	EPSD	COSMIC	5.915	Down-regulation
CMGC_MAPK_p38_MAPK14_ST	O95644	NFATC1	Q16539	MAPK14	S233	S233F	233	Missense	central	0	yes	10.753	0.000	EPSD	COSMIC	5.915	Loss
CMGC_MAPK_p38_MAPK14_ST	O95644	NFATC1	Q16539	MAPK14	S233	R235W	235	Missense	proximal	2	no	10.753	10.255	EPSD	COSMIC	5.915	Down-regulation
CMGC_MAPK_p38_MAPK14_ST	O95644	NFATC1	Q16539	MAPK14	S237	S237P	237	Missense	central	0	yes	10.127	0.000	EPSD	COSMIC	5.915	Loss
CMGC_MAPK_p38_MAPK14_ST	O95644	NFATC1	Q16539	MAPK14	S237	S233F	233	Missense	distal	-4	no	10.127	10.831	EPSD	COSMIC	5.915	Up-regulation
CMGC_MAPK_p38_MAPK14_ST	O95644	NFATC1	Q16539	MAPK14	S237	R235W	235	Missense	proximal	-2	no	10.127	9.601	EPSD	COSMIC	5.915	Down-regulation
CMGC_MAPK_p38_MAPK14_ST	O95644	NFATC1	Q16539	MAPK14	S239	S237P	237	Missense	proximal	-2	no	6.025	6.514	EPSD	COSMIC	5.915	Up-regulation
CMGC_MAPK_p38_MAPK14_ST	O95644	NFATC1	Q16539	MAPK14	S239	S233F	233	Missense	distal	-6	no	6.025	4.261	EPSD	COSMIC	5.915	Loss
CMGC_MAPK_p38_MAPK14_ST	O95644	NFATC1	Q16539	MAPK14	S239	R235W	235	Missense	distal	-4	no	6.025	6.655	EPSD	COSMIC	5.915	Up-regulation
CMGC_MAPK_p38_MAPK14_ST	O95644	NFATC1	Q16539	MAPK14	S241	S237P	237	Missense	distal	-4	no	13.363	13.450	EPSD	COSMIC	5.915	Up-regulation
CMGC_MAPK_p38_MAPK14_ST	O95644	NFATC1	Q16539	MAPK14	S241	R235W	235	Missense	distal	-6	no	13.363	12.045	EPSD	COSMIC	5.915	Down-regulation
CMGC_MAPK_p38_MAPK14_ST	O95644	NFATC1	Q16539	MAPK14	S250	S257F	257	Missense	distal	7	no	6.694	5.824	EPSD	COSMIC	5.915	Loss
CMGC_MAPK_p38_MAPK14_ST	O95644	NFATC1	Q16539	MAPK14	S250	E249K	249	Missense	proximal	-1	no	6.694	6.756	EPSD	COSMIC	5.915	Up-regulation
CMGC_MAPK_p38_MAPK14_ST	O95644	NFATC1	Q16539	MAPK14	S250	R255K	255	Missense	distal	5	no	6.694	6.400	EPSD	COSMIC	5.915	Down-regulation
CMGC_MAPK_p38_MAPK14_ST	O95644	NFATC1	Q16539	MAPK14	S256	S257F	257	Missense	proximal	1	no	5.513	6.793	EPSD	COSMIC	5.915	Gain
CMGC_MAPK_p38_MAPK14_ST	O95644	NFATC1	Q16539	MAPK14	S261	S257F	257	Missense	distal	-4	no	13.340	14.044	EPSD	COSMIC	5.915	Up-regulation
CMGC_MAPK_p38_MAPK14_ST	O95644	NFATC1	Q16539	MAPK14	S261	A260T	260	Missense	proximal	-1	no	13.340	13.396	EPSD	COSMIC	5.915	Up-regulation
CMGC_MAPK_p38_MAPK14_ST	O95644	NFATC1	Q16539	MAPK14	S261	R258I	258	Missense	distal	-3	no	13.340	10.755	EPSD	COSMIC	5.915	Down-regulation
CMGC_MAPK_p38_MAPK14_ST	O95644	NFATC1	Q16539	MAPK14	S261	R255K	255	Missense	distal	-6	no	13.340	12.861	EPSD	COSMIC	5.915	Down-regulation
CMGC_MAPK_p38_MAPK14_ST	O95644	NFATC1	Q16539	MAPK14	S278	T284M	284	Missense	distal	6	no	11.081	11.092	EPSD	COSMIC	5.915	Up-regulation
CMGC_MAPK_p38_MAPK14_ST	O95644	NFATC1	Q16539	MAPK14	S282	S286L	286	Missense	distal	4	no	12.738	11.659	EPSD	COSMIC;GDSC	5.915	Down-regulation
CMGC_MAPK_p38_MAPK14_ST	O95644	NFATC1	Q16539	MAPK14	S282	P287L	287	Missense	distal	5	no	12.738	12.241	EPSD	COSMIC	5.915	Down-regulation
CMGC_MAPK_p38_MAPK14_ST	O95644	NFATC1	Q16539	MAPK14	S282	T284M	284	Missense	proximal	2	no	12.738	12.719	EPSD	COSMIC	5.915	Down-regulation
CMGC_MAPK_p38_MAPK14_ST	O95644	NFATC1	Q16539	MAPK14	T284	S286L	286	Missense	proximal	2	no	10.203	9.714	EPSD	COSMIC;GDSC	5.915	Down-regulation
CMGC_MAPK_p38_MAPK14_ST	O95644	NFATC1	Q16539	MAPK14	T284	P287L	287	Missense	distal	3	no	10.203	10.237	EPSD	COSMIC	5.915	Up-regulation
CMGC_MAPK_p38_MAPK14_ST	O95644	NFATC1	Q16539	MAPK14	T284	T284M	284	Missense	central	0	yes	10.203	0.000	EPSD	COSMIC	5.915	Loss
CMGC_MAPK_p38_MAPK14_ST	O95644	NFATC1	Q16539	MAPK14	S286	S286L	286	Missense	central	0	yes	10.865	0.000	EPSD	COSMIC;GDSC	5.915	Loss
CMGC_MAPK_p38_MAPK14_ST	O95644	NFATC1	Q16539	MAPK14	S286	R292W	292	Missense	distal	6	no	10.865	10.601	EPSD	COSMIC	5.915	Down-regulation
CMGC_MAPK_p38_MAPK14_ST	O95644	NFATC1	Q16539	MAPK14	S286	P287L	287	Missense	proximal	1	no	10.865	2.814	EPSD	COSMIC	5.915	Loss
CMGC_MAPK_p38_MAPK14_ST	O95644	NFATC1	Q16539	MAPK14	S286	R292Q	292	Missense	distal	6	no	10.865	10.877	EPSD	COSMIC	5.915	Up-regulation
CMGC_MAPK_p38_MAPK14_ST	O95644	NFATC1	Q16539	MAPK14	S286	T284M	284	Missense	proximal	-2	no	10.865	10.773	EPSD	COSMIC	5.915	Down-regulation
CMGC_MAPK_p38_MAPK14_ST	O95644	NFATC1	Q16539	MAPK14	S290	S286L	286	Missense	distal	-4	no	9.130	9.730	EPSD	COSMIC;GDSC	5.915	Up-regulation
CMGC_MAPK_p38_MAPK14_ST	O95644	NFATC1	Q16539	MAPK14	S290	R292W	292	Missense	proximal	2	no	9.130	8.632	EPSD	COSMIC	5.915	Down-regulation
CMGC_MAPK_p38_MAPK14_ST	O95644	NFATC1	Q16539	MAPK14	S290	P287L	287	Missense	distal	-3	no	9.130	8.162	EPSD	COSMIC	5.915	Down-regulation
CMGC_MAPK_p38_MAPK14_ST	O95644	NFATC1	Q16539	MAPK14	S290	R292Q	292	Missense	proximal	2	no	9.130	8.704	EPSD	COSMIC	5.915	Down-regulation
CMGC_MAPK_p38_MAPK14_ST	O95644	NFATC1	Q16539	MAPK14	S290	T284M	284	Missense	distal	-6	no	9.130	8.542	EPSD	COSMIC	5.915	Down-regulation
CMGC_MAPK_p38_MAPK14_ST	O95644	NFATC1	Q16539	MAPK14	S359	P363H	363	Missense	distal	4	no	6.576	5.905	EPSD	COSMIC	5.915	Loss
CMGC_MAPK_p38_MAPK14_ST	O95644	NFATC1	Q16539	MAPK14	S403	W396G	396	Missense	distal	-7	no	12.139	12.979	EPSD	COSMIC	5.915	Up-regulation
CMGC_MAPK_p38_MAPK14_ST	O95644	NFATC1	Q16539	MAPK14	S403	P410L	410	Missense	distal	7	no	12.139	11.976	EPSD	COSMIC	5.915	Down-regulation
CMGC_MAPK_p38_MAPK14_ST	O95644	NFATC1	Q16539	MAPK14	S403	S406F	406	Missense	distal	3	no	12.139	12.247	EPSD	COSMIC;CCLE	5.915	Up-regulation
CMGC_MAPK_p38_MAPK14_ST	O95644	NFATC1	Q16539	MAPK14	S403	A397S	397	Missense	distal	-6	no	12.139	12.681	EPSD	COSMIC	5.915	Up-regulation
CMGC_MAPK_p38_MAPK14_ST	O95644	NFATC1	Q16539	MAPK14	S409	P410L	410	Missense	proximal	1	no	13.393	5.342	EPSD	COSMIC	5.915	Loss
CMGC_MAPK_p38_MAPK14_ST	O95644	NFATC1	Q16539	MAPK14	S409	A414T	414	Missense	distal	5	no	13.393	13.865	EPSD	COSMIC	5.915	Up-regulation
CMGC_MAPK_p38_MAPK14_ST	O95644	NFATC1	Q16539	MAPK14	S409	S406F	406	Missense	distal	-3	no	13.393	10.685	EPSD	COSMIC;CCLE	5.915	Down-regulation
CMGC_MAPK_p38_MAPK14_ST	O95644	NFATC1	Q16539	MAPK14	S409	P413H	413	Missense	distal	4	no	13.393	12.722	EPSD	COSMIC;CCLE	5.915	Down-regulation
CMGC_MAPK_p38_MAPK14_ST	O95644	NFATC1	Q16539	MAPK14	T504	T505P	505	Missense	proximal	1	no	0.578	8.031	EPSD	COSMIC	5.915	Gain
CMGC_MAPK_p38_MAPK14_ST	O95644	NFATC1	Q16539	MAPK14	S723	V718L	718	Missense	distal	-5	no	10.562	10.688	EPSD	COSMIC	5.915	Up-regulation
CMGC_MAPK_p38_MAPK14_ST	O95644	NFATC1	Q16539	MAPK14	S723	G716V	716	Missense	distal	-7	no	10.562	9.924	EPSD	COSMIC	5.915	Down-regulation
CMGC_MAPK_p38_MAPK14_ST	O95644	NFATC1	Q16539	MAPK14	S723	L725F	725	Missense	proximal	2	no	10.562	10.385	EPSD	COSMIC	5.915	Down-regulation
CMGC_MAPK_p38_MAPK14_ST	O95644	NFATC1	Q16539	MAPK14	S723	P724L	724	Missense	proximal	1	no	10.562	2.511	EPSD	COSMIC	5.915	Loss
CMGC_MAPK_p38_MAPK14_ST	O95644	NFATC1	Q16539	MAPK14	S723	R727K	727	Missense	distal	4	no	10.562	11.313	EPSD	COSMIC	5.915	Up-regulation
CMGC_MAPK_p38_MAPK14_ST	O95644	NFATC1	Q16539	MAPK14	S723	P717L	717	Missense	distal	-6	no	10.562	9.949	EPSD	COSMIC	5.915	Down-regulation
CMGC_MAPK_p38_MAPK14_ST	O95644	NFATC1	Q16539	MAPK14	S765	P762L	762	Missense	distal	-3	no	10.469	9.501	EPSD	COSMIC	5.915	Down-regulation
CMGC_MAPK_p38_MAPK14_ST	O95644	NFATC1	Q16539	MAPK14	S765	P762S	762	Missense	distal	-3	no	10.469	11.232	EPSD	COSMIC	5.915	Up-regulation
CMGC_MAPK_p38_MAPK14_ST	O95644	NFATC1	Q16539	MAPK14	S765	D770N	770	Missense	distal	5	no	10.469	10.677	EPSD	COSMIC	5.915	Up-regulation
CMGC_MAPK_p38_MAPK14_ST	O95644	NFATC1	Q16539	MAPK14	S765	A760T	760	Missense	distal	-5	no	10.469	10.798	EPSD	COSMIC	5.915	Up-regulation
CMGC_MAPK_p38_MAPK14_ST	O95644	NFATC1	Q16539	MAPK14	S765	D770Y	770	Missense	distal	5	no	10.469	10.734	EPSD	COSMIC	5.915	Up-regulation
CMGC_MAPK_p38_MAPK14_ST	O95644	NFATC1	Q16539	MAPK14	S765	V764M	764	Missense	proximal	-1	no	10.469	10.376	EPSD	COSMIC	5.915	Down-regulation
CMGC_MAPK_p38_MAPK14_ST	O95644	NFATC1	Q16539	MAPK14	S772	A775S	775	Missense	distal	3	no	12.370	12.355	EPSD	COSMIC	5.915	Down-regulation
CMGC_MAPK_p38_MAPK14_ST	O95644	NFATC1	Q16539	MAPK14	S772	D770N	770	Missense	proximal	-2	no	12.370	12.884	EPSD	COSMIC	5.915	Up-regulation
CMGC_MAPK_p38_MAPK14_ST	O95644	NFATC1	Q16539	MAPK14	S772	D770Y	770	Missense	proximal	-2	no	12.370	13.573	EPSD	COSMIC	5.915	Up-regulation
CMGC_MAPK_p38_MAPK14_ST	O95644	NFATC1	Q16539	MAPK14	S782	A781V	781	Missense	proximal	-1	no	7.523	7.679	EPSD	COSMIC	5.915	Up-regulation
CMGC_MAPK_p38_MAPK14_ST	O95644	NFATC1	Q16539	MAPK14	S782	A775S	775	Missense	distal	-7	no	7.523	7.410	EPSD	COSMIC	5.915	Down-regulation
CMGC_MAPK_p38_MAPK14_ST	O95644	NFATC1	Q16539	MAPK14	S813	P806L	806	Missense	distal	-7	no	11.622	11.429	EPSD	COSMIC	5.915	Down-regulation
CMGC_MAPK_p38_MAPK14_ST	O95644	NFATC1	Q16539	MAPK14	S813	P819L	819	Missense	distal	6	no	11.622	11.483	EPSD	COSMIC	5.915	Down-regulation
CMGC_MAPK_p38_MAPK14_ST	O95644	NFATC1	Q16539	MAPK14	S813	G815V	815	Missense	proximal	2	no	11.622	11.423	EPSD	COSMIC	5.915	Down-regulation
CMGC_MAPK_p38_MAPK14_ST	O95644	NFATC1	Q16539	MAPK14	S813	S813L	813	Missense	central	0	yes	11.622	0.000	EPSD	COSMIC	5.915	Loss
CMGC_MAPK_p38_MAPK14_ST	O95644	NFATC1	Q16539	MAPK14	S887	T881M	881	Missense	distal	-6	no	12.395	11.807	EPSD	COSMIC	5.915	Down-regulation
CMGC_MAPK_p38_MAPK14_ST	O95644	NFATC1	Q16539	MAPK14	S887	R893W	893	Missense	distal	6	no	12.395	12.131	EPSD	COSMIC	5.915	Down-regulation
CMGC_MAPK_p38_MAPK14_ST	O95644	NFATC1	Q16539	MAPK14	S887	R883H	883	Missense	distal	-4	no	12.395	12.606	EPSD	COSMIC	5.915	Up-regulation
CMGC_MAPK_p38_MAPK14_ST	O95644	NFATC1	Q16539	MAPK14	S887	A890V	890	Missense	distal	3	no	12.395	12.423	EPSD	COSMIC	5.915	Up-regulation
CMGC_MAPK_p38_MAPK14_ST	O95644	NFATC1	Q16539	MAPK14	S903	A907V	907	Missense	distal	4	no	10.463	10.029	EPSD	COSMIC	5.915	Down-regulation
CMGC_MAPK_p38_MAPK14_ST	Q99626	CDX2	Q16539	MAPK14	S283	R276K	276	Missense	distal	-7	no	10.883	11.149	PhosphoSitePlus	COSMIC	5.915	Up-regulation
CMGC_MAPK_p38_MAPK14_ST	Q99626	CDX2	Q16539	MAPK14	S283	L288M	288	Missense	distal	5	no	10.883	11.352	PhosphoSitePlus	COSMIC	5.915	Up-regulation
CMGC_MAPK_p38_MAPK14_ST	Q99626	CDX2	Q16539	MAPK14	S286	S291A	291	Missense	distal	5	no	8.061	7.422	EPSD	COSMIC;GDSC;CCLE	5.915	Down-regulation
CMGC_MAPK_p38_MAPK14_ST	Q99626	CDX2	Q16539	MAPK14	S286	L288M	288	Missense	proximal	2	no	8.061	8.296	EPSD	COSMIC	5.915	Up-regulation
CMGC_MAPK_p38_MAPK14_ST	Q99626	CDX2	Q16539	MAPK14	S286	S291L	291	Missense	distal	5	no	8.061	7.113	EPSD	COSMIC	5.915	Down-regulation
CMGC_MAPK_p38_MAPK14_ST	Q15075	EEA1	Q16539	MAPK14	T9	Q16E	16	Missense	distal	7	no	9.391	9.767	EPSD	COSMIC	5.915	Up-regulation
CMGC_MAPK_p38_MAPK14_ST	Q15075	EEA1	Q16539	MAPK14	T25	D21V	21	Missense	distal	-4	no	12.865	12.694	EPSD	COSMIC	5.915	Down-regulation
CMGC_MAPK_p38_MAPK14_ST	P13726	F3	Q16539	MAPK14	S120	G122E	122	Missense	proximal	2	no	6.215	6.409	EPSD	COSMIC	5.915	Up-regulation
CMGC_MAPK_p38_MAPK14_ST	P13726	F3	Q16539	MAPK14	S290	V294A	294	Missense	distal	4	no	11.615	12.049	PhosphoSitePlus;EPSD	COSMIC	5.915	Up-regulation
CMGC_MAPK_p38_MAPK14_ST	P13726	F3	Q16539	MAPK14	S290	P291L	291	Missense	proximal	1	no	11.615	3.564	PhosphoSitePlus;EPSD	COSMIC	5.915	Loss
CMGC_MAPK_p38_MAPK14_ST	O75676	RPS6KA4	Q16539	MAPK14	S343	P344L	344	Missense	proximal	1	no	13.382	5.331	EPSD	COSMIC	5.915	Loss
CMGC_MAPK_p38_MAPK14_ST	O75676	RPS6KA4	Q16539	MAPK14	S343	P350S	350	Missense	distal	7	no	13.382	13.604	EPSD	COSMIC	5.915	Up-regulation
CMGC_MAPK_p38_MAPK14_ST	O75676	RPS6KA4	Q16539	MAPK14	S343	P349L	349	Missense	distal	6	no	13.382	13.243	EPSD	COSMIC	5.915	Down-regulation
CMGC_MAPK_p38_MAPK14_ST	O75676	RPS6KA4	Q16539	MAPK14	S343	P340H	340	Missense	distal	-3	no	13.382	12.904	EPSD	COSMIC	5.915	Down-regulation
CMGC_MAPK_p38_MAPK14_ST	O75676	RPS6KA4	Q16539	MAPK14	S347	D352E	352	Missense	distal	5	no	13.505	14.011	EPSD	COSMIC	5.915	Up-regulation
CMGC_MAPK_p38_MAPK14_ST	O75676	RPS6KA4	Q16539	MAPK14	S347	P344L	344	Missense	distal	-3	no	13.505	12.537	EPSD	COSMIC	5.915	Down-regulation
CMGC_MAPK_p38_MAPK14_ST	O75676	RPS6KA4	Q16539	MAPK14	S347	P350S	350	Missense	distal	3	no	13.505	13.465	EPSD	COSMIC	5.915	Down-regulation
CMGC_MAPK_p38_MAPK14_ST	O75676	RPS6KA4	Q16539	MAPK14	S347	P349L	349	Missense	proximal	2	no	13.505	13.392	EPSD	COSMIC	5.915	Down-regulation
CMGC_MAPK_p38_MAPK14_ST	O75676	RPS6KA4	Q16539	MAPK14	S347	P340H	340	Missense	distal	-7	no	13.505	13.128	EPSD	COSMIC	5.915	Down-regulation
CMGC_MAPK_p38_MAPK14_ST	O75676	RPS6KA4	Q16539	MAPK14	S360	P364L	364	Missense	distal	4	no	7.805	7.166	EPSD	COSMIC	5.915	Down-regulation
CMGC_MAPK_p38_MAPK14_ST	O75676	RPS6KA4	Q16539	MAPK14	T542	G544R	544	Missense	proximal	2	no	8.890	8.974	EPSD	COSMIC	5.915	Up-regulation
CMGC_MAPK_p38_MAPK14_ST	O75676	RPS6KA4	Q16539	MAPK14	T542	A539S	539	Missense	distal	-3	no	8.890	9.302	EPSD	COSMIC;GDSC;CCLE	5.915	Up-regulation
CMGC_MAPK_p38_MAPK14_ST	O75676	RPS6KA4	Q16539	MAPK14	T542	T542M	542	Missense	central	0	yes	8.890	0.000	EPSD	COSMIC	5.915	Loss
CMGC_MAPK_p38_MAPK14_ST	O75676	RPS6KA4	Q16539	MAPK14	T568	T568M	568	Missense	central	0	yes	11.294	0.000	EPSD	COSMIC	5.915	Loss
CMGC_MAPK_p38_MAPK14_ST	O75676	RPS6KA4	Q16539	MAPK14	T568	P562F	562	Missense	distal	-6	no	11.294	10.136	EPSD	COSMIC	5.915	Down-regulation
CMGC_MAPK_p38_MAPK14_ST	O75676	RPS6KA4	Q16539	MAPK14	S672	A679P	679	Missense	distal	7	no	6.445	6.201	EPSD	COSMIC	5.915	Down-regulation
CMGC_MAPK_p38_MAPK14_ST	O75676	RPS6KA4	Q16539	MAPK14	S672	R669Q	669	Missense	distal	-3	no	6.445	4.666	EPSD	COSMIC	5.915	Loss
CMGC_MAPK_p38_MAPK14_ST	O75676	RPS6KA4	Q16539	MAPK14	S672	S672L	672	Missense	central	0	yes	6.445	0.000	EPSD	COSMIC	5.915	Loss
CMGC_MAPK_p38_MAPK14_ST	O75676	RPS6KA4	Q16539	MAPK14	S678	A679P	679	Missense	proximal	1	no	5.850	12.169	EPSD	COSMIC	5.915	Gain
CMGC_MAPK_p38_MAPK14_ST	O75676	RPS6KA4	Q16539	MAPK14	S678	P683S	683	Missense	distal	5	no	5.850	6.301	EPSD	COSMIC;CCLE	5.915	Gain
CMGC_MAPK_p38_MAPK14_ST	O75676	RPS6KA4	Q16539	MAPK14	S682	R686W	686	Missense	distal	4	no	12.080	10.806	EPSD	COSMIC	5.915	Down-regulation
CMGC_MAPK_p38_MAPK14_ST	O75676	RPS6KA4	Q16539	MAPK14	S682	R680C	680	Missense	proximal	-2	no	12.080	11.145	EPSD	COSMIC	5.915	Down-regulation
CMGC_MAPK_p38_MAPK14_ST	O75676	RPS6KA4	Q16539	MAPK14	S682	R680L	680	Missense	proximal	-2	no	12.080	11.389	EPSD	COSMIC	5.915	Down-regulation
CMGC_MAPK_p38_MAPK14_ST	O75676	RPS6KA4	Q16539	MAPK14	S682	A679P	679	Missense	distal	-3	no	12.080	11.729	EPSD	COSMIC	5.915	Down-regulation
CMGC_MAPK_p38_MAPK14_ST	O75676	RPS6KA4	Q16539	MAPK14	S682	P683S	683	Missense	proximal	1	no	12.080	4.796	EPSD	COSMIC;CCLE	5.915	Loss
CMGC_MAPK_p38_MAPK14_ST	O75676	RPS6KA4	Q16539	MAPK14	S682	S682L	682	Missense	central	0	yes	12.080	0.000	EPSD	COSMIC	5.915	Loss
CMGC_MAPK_p38_MAPK14_ST	O75676	RPS6KA4	Q16539	MAPK14	S682	P684L	684	Missense	proximal	2	no	12.080	11.968	EPSD	COSMIC	5.915	Down-regulation
CMGC_MAPK_p38_MAPK14_ST	O75676	RPS6KA4	Q16539	MAPK14	T687	R686W	686	Missense	proximal	-1	no	10.489	10.777	EPSD	COSMIC	5.915	Up-regulation
CMGC_MAPK_p38_MAPK14_ST	O75676	RPS6KA4	Q16539	MAPK14	T687	R680C	680	Missense	distal	-7	no	10.489	10.097	EPSD	COSMIC	5.915	Down-regulation
CMGC_MAPK_p38_MAPK14_ST	O75676	RPS6KA4	Q16539	MAPK14	T687	R680L	680	Missense	distal	-7	no	10.489	10.377	EPSD	COSMIC	5.915	Down-regulation
CMGC_MAPK_p38_MAPK14_ST	O75676	RPS6KA4	Q16539	MAPK14	T687	E692K	692	Missense	distal	5	no	10.489	9.922	EPSD	COSMIC	5.915	Down-regulation
CMGC_MAPK_p38_MAPK14_ST	O75676	RPS6KA4	Q16539	MAPK14	T687	P683S	683	Missense	distal	-4	no	10.489	10.402	EPSD	COSMIC;CCLE	5.915	Down-regulation
CMGC_MAPK_p38_MAPK14_ST	O75676	RPS6KA4	Q16539	MAPK14	T687	S694C	694	Missense	distal	7	no	10.489	9.924	EPSD	COSMIC	5.915	Down-regulation
CMGC_MAPK_p38_MAPK14_ST	O75676	RPS6KA4	Q16539	MAPK14	T687	S694F	694	Missense	distal	7	no	10.489	9.619	EPSD	COSMIC	5.915	Down-regulation
CMGC_MAPK_p38_MAPK14_ST	O75676	RPS6KA4	Q16539	MAPK14	T687	S682L	682	Missense	distal	-5	no	10.489	11.218	EPSD	COSMIC	5.915	Up-regulation
CMGC_MAPK_p38_MAPK14_ST	O75676	RPS6KA4	Q16539	MAPK14	T687	V690M	690	Missense	distal	3	no	10.489	10.484	EPSD	COSMIC	5.915	Down-regulation
CMGC_MAPK_p38_MAPK14_ST	O75676	RPS6KA4	Q16539	MAPK14	T687	P684L	684	Missense	distal	-3	no	10.489	9.522	EPSD	COSMIC	5.915	Down-regulation
CMGC_MAPK_p38_MAPK14_ST	O75676	RPS6KA4	Q16539	MAPK14	T739	K732T	732	Missense	distal	-7	no	6.015	5.848	EPSD	COSMIC	5.915	Loss
CMGC_MAPK_p38_MAPK14_ST	O75676	RPS6KA4	Q16539	MAPK14	T739	P746T	746	Missense	distal	7	no	6.015	5.916	EPSD	COSMIC	5.915	Down-regulation
CMGC_MAPK_p38_MAPK14_ST	O75676	RPS6KA4	Q16539	MAPK14	T739	R736Q	736	Missense	distal	-3	no	6.015	4.236	EPSD	COSMIC;GDSC;CCLE	5.915	Loss
CMGC_MAPK_p38_MAPK14_ST	O75676	RPS6KA4	Q16539	MAPK14	T739	R742H	742	Missense	distal	3	no	6.015	6.086	EPSD	COSMIC	5.915	Up-regulation
CMGC_MAPK_p38_MAPK14_ST	O75676	RPS6KA4	Q16539	MAPK14	T739	R736W	736	Missense	distal	-3	no	6.015	3.658	EPSD	COSMIC	5.915	Loss
CMGC_MAPK_p38_MAPK14_ST	O75676	RPS6KA4	Q16539	MAPK14	S745	A749T	749	Missense	distal	4	no	12.491	12.536	EPSD	COSMIC	5.915	Up-regulation
CMGC_MAPK_p38_MAPK14_ST	O75676	RPS6KA4	Q16539	MAPK14	S745	P746T	746	Missense	proximal	1	no	12.491	5.038	EPSD	COSMIC	5.915	Loss
CMGC_MAPK_p38_MAPK14_ST	O75676	RPS6KA4	Q16539	MAPK14	S745	R742H	742	Missense	distal	-3	no	12.491	10.737	EPSD	COSMIC	5.915	Down-regulation
CMGC_MAPK_p38_MAPK14_ST	O75676	RPS6KA4	Q16539	MAPK14	S745	P751L	751	Missense	distal	6	no	12.491	12.352	EPSD	COSMIC	5.915	Down-regulation
CMGC_MAPK_p38_MAPK14_ST	P22415	USF1	Q16539	MAPK14	T153	P154A	154	Missense	proximal	1	no	9.923	3.604	PhosphoSitePlus	COSMIC	5.915	Loss
CMGC_MAPK_p38_MAPK14_ST	P22415	USF1	Q16539	MAPK14	T153	G150W	150	Missense	distal	-3	no	9.923	9.016	PhosphoSitePlus	COSMIC;GDSC;CCLE	5.915	Down-regulation
CMGC_MAPK_p38_MAPK14_ST	P22415	USF1	Q16539	MAPK14	T153	P155T	155	Missense	proximal	2	no	9.923	10.064	PhosphoSitePlus	COSMIC	5.915	Up-regulation
CMGC_MAPK_p38_MAPK14_ST	P22415	USF1	Q16539	MAPK14	S186	R181S	181	Missense	distal	-5	no	10.311	10.092	EPSD	COSMIC	5.915	Down-regulation
CMGC_MAPK_p38_MAPK14_ST	P22415	USF1	Q16539	MAPK14	S186	T182I	182	Missense	distal	-4	no	10.311	10.201	EPSD	COSMIC	5.915	Down-regulation
CMGC_MAPK_p38_MAPK14_ST	P22415	USF1	Q16539	MAPK14	S186	A191S	191	Missense	distal	5	no	10.311	10.949	EPSD	COSMIC	5.915	Up-regulation
CMGC_MAPK_p38_MAPK14_ST	P22415	USF1	Q16539	MAPK14	S186	R193W	193	Missense	distal	7	no	10.311	9.622	EPSD	COSMIC	5.915	Down-regulation
CMGC_MAPK_p38_MAPK14_ST	P22415	USF1	Q16539	MAPK14	S186	P187T	187	Missense	proximal	1	no	10.311	2.857	EPSD	COSMIC	5.915	Loss
CMGC_MAPK_p38_MAPK14_ST	P22415	USF1	Q16539	MAPK14	S186	Y185H	185	Missense	proximal	-1	no	10.311	10.358	EPSD	COSMIC	5.915	Up-regulation
CMGC_MAPK_p38_MAPK14_ST	P22415	USF1	Q16539	MAPK14	S186	P192A	192	Missense	distal	6	no	10.311	10.354	EPSD	COSMIC	5.915	Up-regulation
CMGC_MAPK_p38_MAPK14_ST	P22415	USF1	Q16539	MAPK14	S186	P184A	184	Missense	proximal	-2	no	10.311	9.648	EPSD	COSMIC	5.915	Down-regulation
CMGC_MAPK_p38_MAPK14_ST	P10275	AR	Q16539	MAPK14	S83	Q79E	79	Missense	distal	-4	no	10.343	9.665	EPSD	COSMIC	5.915	Down-regulation
CMGC_MAPK_p38_MAPK14_ST	P10275	AR	Q16539	MAPK14	S83	Q86K	86	Missense	distal	3	no	10.343	10.319	EPSD	COSMIC	5.915	Down-regulation
CMGC_MAPK_p38_MAPK14_ST	P10275	AR	Q16539	MAPK14	S83	E81Q	81	Missense	proximal	-2	no	10.343	9.589	EPSD	COSMIC	5.915	Down-regulation
CMGC_MAPK_p38_MAPK14_ST	P10275	AR	Q16539	MAPK14	S83	Q90H	90	Missense	distal	7	no	10.343	10.003	EPSD	COSMIC	5.915	Down-regulation
CMGC_MAPK_p38_MAPK14_ST	P10275	AR	Q16539	MAPK14	S83	Q79R	79	Missense	distal	-4	no	10.343	9.975	EPSD	COSMIC	5.915	Down-regulation
CMGC_MAPK_p38_MAPK14_ST	P10275	AR	Q16539	MAPK14	S83	P84H	84	Missense	proximal	1	no	10.343	-3.311	EPSD	COSMIC	5.915	Loss
CMGC_MAPK_p38_MAPK14_ST	P10275	AR	Q16539	MAPK14	S96	S96Y	96	Missense	central	0	yes	7.133	0.000	EPSD	COSMIC	5.915	Loss
CMGC_MAPK_p38_MAPK14_ST	P10275	AR	Q16539	MAPK14	S96	Q90H	90	Missense	distal	-6	no	7.133	6.840	EPSD	COSMIC	5.915	Down-regulation
CMGC_MAPK_p38_MAPK14_ST	P10275	AR	Q16539	MAPK14	S96	S96F	96	Missense	central	0	yes	7.133	0.000	EPSD	COSMIC	5.915	Loss
CMGC_MAPK_p38_MAPK14_ST	P10275	AR	Q16539	MAPK14	S258	L257P	257	Missense	proximal	-1	no	8.031	7.845	EPSD	COSMIC	5.915	Down-regulation
CMGC_MAPK_p38_MAPK14_ST	P10275	AR	Q16539	MAPK14	S258	R264Q	264	Missense	distal	6	no	8.031	8.043	EPSD	COSMIC	5.915	Up-regulation
CMGC_MAPK_p38_MAPK14_ST	P10275	AR	Q16539	MAPK14	S258	E252G	252	Missense	distal	-6	no	8.031	7.720	EPSD	COSMIC	5.915	Down-regulation
CMGC_MAPK_p38_MAPK14_ST	P10275	AR	Q16539	MAPK14	S258	E252K	252	Missense	distal	-6	no	8.031	7.616	EPSD	COSMIC	5.915	Down-regulation
CMGC_MAPK_p38_MAPK14_ST	P10275	AR	Q16539	MAPK14	S258	E255K	255	Missense	distal	-3	no	8.031	7.638	EPSD	COSMIC	5.915	Down-regulation
CMGC_MAPK_p38_MAPK14_ST	P10275	AR	Q16539	MAPK14	T282	R280H	280	Missense	proximal	-2	no	10.084	8.506	EPSD	COSMIC	5.915	Down-regulation
CMGC_MAPK_p38_MAPK14_ST	P10275	AR	Q16539	MAPK14	T282	E289G	289	Missense	distal	7	no	10.084	9.723	EPSD	COSMIC	5.915	Down-regulation
CMGC_MAPK_p38_MAPK14_ST	P10275	AR	Q16539	MAPK14	T282	P276S	276	Missense	distal	-6	no	10.084	10.690	EPSD	COSMIC	5.915	Up-regulation
CMGC_MAPK_p38_MAPK14_ST	P10275	AR	Q16539	MAPK14	T282	P283S	283	Missense	proximal	1	no	10.084	2.800	EPSD	COSMIC	5.915	Loss
CMGC_MAPK_p38_MAPK14_ST	P10275	AR	Q16539	MAPK14	T282	A278T	278	Missense	distal	-4	no	10.084	10.321	EPSD	COSMIC	5.915	Up-regulation
CMGC_MAPK_p38_MAPK14_ST	P10275	AR	Q16539	MAPK14	T282	A285D	285	Missense	distal	3	no	10.084	10.120	EPSD	COSMIC	5.915	Up-regulation
CMGC_MAPK_p38_MAPK14_ST	P10275	AR	Q16539	MAPK14	T282	A278V	278	Missense	distal	-4	no	10.084	10.366	EPSD	COSMIC	5.915	Up-regulation
CMGC_MAPK_p38_MAPK14_ST	P10275	AR	Q16539	MAPK14	T282	A285V	285	Missense	distal	3	no	10.084	10.111	EPSD	COSMIC	5.915	Up-regulation
CMGC_MAPK_p38_MAPK14_ST	P10275	AR	Q16539	MAPK14	S298	D296G	296	Missense	proximal	-2	no	5.314	6.065	EPSD	COSMIC	5.915	Gain
CMGC_MAPK_p38_MAPK14_ST	P10275	AR	Q16539	MAPK14	S298	D296E	296	Missense	proximal	-2	no	5.314	6.743	EPSD	COSMIC	5.915	Gain
CMGC_MAPK_p38_MAPK14_ST	P10275	AR	Q16539	MAPK14	S310	D305N	305	Missense	distal	-5	no	10.302	10.143	EPSD	COSMIC	5.915	Down-regulation
CMGC_MAPK_p38_MAPK14_ST	P10275	AR	Q16539	MAPK14	S310	S310F	310	Missense	central	0	yes	10.302	0.000	EPSD	COSMIC	5.915	Loss
CMGC_MAPK_p38_MAPK14_ST	P10275	AR	Q16539	MAPK14	S310	E304K	304	Missense	distal	-6	no	10.302	9.888	EPSD	COSMIC	5.915	Down-regulation
CMGC_MAPK_p38_MAPK14_ST	P10275	AR	Q16539	MAPK14	S310	T306I	306	Missense	distal	-4	no	10.302	10.192	EPSD	COSMIC;GDSC;CCLE	5.915	Down-regulation
CMGC_MAPK_p38_MAPK14_ST	P10275	AR	Q16539	MAPK14	S310	F312L	312	Missense	proximal	2	no	10.302	10.479	EPSD	COSMIC	5.915	Up-regulation
CMGC_MAPK_p38_MAPK14_ST	P10275	AR	Q16539	MAPK14	S330	G329C	329	Missense	proximal	-1	no	6.855	6.798	EPSD	COSMIC;GDSC;CCLE	5.915	Down-regulation
CMGC_MAPK_p38_MAPK14_ST	P10275	AR	Q16539	MAPK14	S424	G421R	421	Missense	distal	-3	no	5.555	7.005	EPSD	COSMIC	5.915	Gain
CMGC_MAPK_p38_MAPK14_ST	P10275	AR	Q16539	MAPK14	S426	A430T	430	Missense	distal	4	no	12.624	12.669	EPSD	COSMIC	5.915	Up-regulation
CMGC_MAPK_p38_MAPK14_ST	P10275	AR	Q16539	MAPK14	S426	A420E	420	Missense	distal	-6	no	12.624	12.997	EPSD	COSMIC	5.915	Up-regulation
CMGC_MAPK_p38_MAPK14_ST	P10275	AR	Q16539	MAPK14	S426	G421V	421	Missense	distal	-5	no	12.624	12.847	EPSD	COSMIC	5.915	Up-regulation
CMGC_MAPK_p38_MAPK14_ST	P10275	AR	Q16539	MAPK14	S426	A430S	430	Missense	distal	4	no	12.624	12.930	EPSD	COSMIC	5.915	Up-regulation
CMGC_MAPK_p38_MAPK14_ST	P10275	AR	Q16539	MAPK14	S426	G421R	421	Missense	distal	-5	no	12.624	12.462	EPSD	COSMIC	5.915	Down-regulation
CMGC_MAPK_p38_MAPK14_ST	P10275	AR	Q16539	MAPK14	S426	S433L	433	Missense	distal	7	no	12.624	12.240	EPSD	COSMIC	5.915	Down-regulation
CMGC_MAPK_p38_MAPK14_ST	P10275	AR	Q16539	MAPK14	S426	S424C	424	Missense	proximal	-2	no	12.624	11.489	EPSD	COSMIC	5.915	Down-regulation
CMGC_MAPK_p38_MAPK14_ST	P10275	AR	Q16539	MAPK14	S426	S424F	424	Missense	proximal	-2	no	12.624	11.901	EPSD	COSMIC	5.915	Down-regulation
CMGC_MAPK_p38_MAPK14_ST	P10275	AR	Q16539	MAPK14	S516	P515H	515	Missense	proximal	-1	no	10.977	10.932	EPSD	COSMIC	5.915	Down-regulation
CMGC_MAPK_p38_MAPK14_ST	P10275	AR	Q16539	MAPK14	S516	E523K	523	Missense	distal	7	no	10.977	10.270	EPSD	COSMIC	5.915	Down-regulation
CMGC_MAPK_p38_MAPK14_ST	P10275	AR	Q16539	MAPK14	S516	P515S	515	Missense	proximal	-1	no	10.977	10.884	EPSD	COSMIC	5.915	Down-regulation
CMGC_MAPK_p38_MAPK14_ST	P10275	AR	Q16539	MAPK14	T649	E643K	643	Missense	distal	-6	no	7.228	6.813	EPSD	COSMIC	5.915	Down-regulation
CMGC_MAPK_p38_MAPK14_ST	P10275	AR	Q16539	MAPK14	T649	A646D	646	Missense	distal	-3	no	7.228	6.651	EPSD	COSMIC	5.915	Down-regulation
CMGC_MAPK_p38_MAPK14_ST	P10275	AR	Q16539	MAPK14	T649	S648R	648	Missense	proximal	-1	no	7.228	7.120	EPSD	COSMIC	5.915	Down-regulation
CMGC_MAPK_p38_MAPK14_ST	P10275	AR	Q16539	MAPK14	T649	S648N	648	Missense	proximal	-1	no	7.228	7.300	EPSD	COSMIC	5.915	Up-regulation
CMGC_MAPK_p38_MAPK14_ST	P10275	AR	Q16539	MAPK14	T649	E654K	654	Missense	distal	5	no	7.228	6.661	EPSD	COSMIC	5.915	Down-regulation
CMGC_MAPK_p38_MAPK14_ST	P10275	AR	Q16539	MAPK14	T649	S647F	647	Missense	proximal	-2	no	7.228	6.504	EPSD	COSMIC	5.915	Down-regulation
CMGC_MAPK_p38_MAPK14_ST	P10275	AR	Q16539	MAPK14	T649	E655D	655	Missense	distal	6	no	7.228	7.127	EPSD	COSMIC	5.915	Down-regulation
CMGC_MAPK_p38_MAPK14_ST	P10275	AR	Q16539	MAPK14	S651	A646D	646	Missense	distal	-5	no	13.990	14.502	PhosphoSitePlus	COSMIC	5.915	Up-regulation
CMGC_MAPK_p38_MAPK14_ST	P10275	AR	Q16539	MAPK14	S651	S648R	648	Missense	distal	-3	no	13.990	14.503	PhosphoSitePlus	COSMIC	5.915	Up-regulation
CMGC_MAPK_p38_MAPK14_ST	P10275	AR	Q16539	MAPK14	S651	S648N	648	Missense	distal	-3	no	13.990	12.843	PhosphoSitePlus	COSMIC	5.915	Down-regulation
CMGC_MAPK_p38_MAPK14_ST	P10275	AR	Q16539	MAPK14	S651	E654K	654	Missense	distal	3	no	13.990	14.038	PhosphoSitePlus	COSMIC	5.915	Up-regulation
CMGC_MAPK_p38_MAPK14_ST	P10275	AR	Q16539	MAPK14	S651	S647F	647	Missense	distal	-4	no	13.990	14.695	PhosphoSitePlus	COSMIC	5.915	Up-regulation
CMGC_MAPK_p38_MAPK14_ST	P10275	AR	Q16539	MAPK14	S651	E655D	655	Missense	distal	4	no	13.990	12.321	PhosphoSitePlus	COSMIC	5.915	Down-regulation
CMGC_MAPK_p38_MAPK14_ST	P10275	AR	Q16539	MAPK14	S792	H790Q	790	Missense	proximal	-2	no	5.074	6.326	EPSD	COSMIC	5.915	Gain
CMGC_MAPK_p38_MAPK14_ST	P06400	RB1	Q16539	MAPK14	T5	P6S	6	Missense	proximal	1	no	10.335	3.052	EPSD	COSMIC	5.915	Loss
CMGC_MAPK_p38_MAPK14_ST	P06400	RB1	Q16539	MAPK14	T5	P2S	2	Missense	distal	-3	no	10.335	11.099	EPSD	COSMIC	5.915	Up-regulation
CMGC_MAPK_p38_MAPK14_ST	P06400	RB1	Q16539	MAPK14	T5	T5N	5	Missense	central	0	yes	10.335	0.000	EPSD	COSMIC	5.915	Loss
CMGC_MAPK_p38_MAPK14_ST	P06400	RB1	Q16539	MAPK14	T5	R7Q	7	Missense	proximal	2	no	10.335	9.909	EPSD	COSMIC	5.915	Down-regulation
CMGC_MAPK_p38_MAPK14_ST	P06400	RB1	Q16539	MAPK14	S149	V144S	144	Missense	distal	-5	no	6.456	5.852	EPSD	COSMIC	5.915	Loss
CMGC_MAPK_p38_MAPK14_ST	P06400	RB1	Q16539	MAPK14	S149	R150S	150	Missense	proximal	1	no	6.456	7.108	EPSD	COSMIC	5.915	Up-regulation
CMGC_MAPK_p38_MAPK14_ST	P06400	RB1	Q16539	MAPK14	S149	D156H	156	Missense	distal	7	no	6.456	5.934	EPSD	COSMIC	5.915	Down-regulation
CMGC_MAPK_p38_MAPK14_ST	P06400	RB1	Q16539	MAPK14	S230	K228R	228	Missense	proximal	-2	no	10.059	10.661	EPSD	COSMIC;GDSC;CCLE	5.915	Up-regulation
CMGC_MAPK_p38_MAPK14_ST	P06400	RB1	Q16539	MAPK14	S230	I227N	227	Missense	distal	-3	no	10.059	10.983	EPSD	COSMIC	5.915	Up-regulation
CMGC_MAPK_p38_MAPK14_ST	P06400	RB1	Q16539	MAPK14	S230	P232L	232	Missense	proximal	2	no	10.059	9.946	EPSD	COSMIC	5.915	Down-regulation
CMGC_MAPK_p38_MAPK14_ST	P06400	RB1	Q16539	MAPK14	S249	V243A	243	Missense	distal	-6	no	10.723	11.211	EPSD;PhosphoSitePlus	COSMIC	5.915	Up-regulation
CMGC_MAPK_p38_MAPK14_ST	P06400	RB1	Q16539	MAPK14	S249	P250S	250	Missense	proximal	1	no	10.723	3.439	EPSD;PhosphoSitePlus	COSMIC	5.915	Loss
CMGC_MAPK_p38_MAPK14_ST	P06400	RB1	Q16539	MAPK14	T252	Q257R	257	Missense	distal	5	no	9.952	10.301	PhosphoSitePlus;EPSD	COSMIC	5.915	Up-regulation
CMGC_MAPK_p38_MAPK14_ST	P06400	RB1	Q16539	MAPK14	T252	P250S	250	Missense	proximal	-2	no	9.952	9.463	PhosphoSitePlus;EPSD	COSMIC	5.915	Down-regulation
CMGC_MAPK_p38_MAPK14_ST	P06400	RB1	Q16539	MAPK14	S350	E352K	352	Missense	proximal	2	no	7.284	6.970	EPSD	COSMIC	5.915	Down-regulation
CMGC_MAPK_p38_MAPK14_ST	P06400	RB1	Q16539	MAPK14	T353	E352K	352	Missense	proximal	-1	no	7.218	7.279	EPSD	COSMIC	5.915	Up-regulation
CMGC_MAPK_p38_MAPK14_ST	P06400	RB1	Q16539	MAPK14	T353	R358Q	358	Missense	distal	5	no	7.218	6.868	EPSD	COSMIC;CCLE	5.915	Down-regulation
CMGC_MAPK_p38_MAPK14_ST	P06400	RB1	Q16539	MAPK14	T356	E352K	352	Missense	distal	-4	no	12.525	12.751	EPSD	COSMIC	5.915	Up-regulation
CMGC_MAPK_p38_MAPK14_ST	P06400	RB1	Q16539	MAPK14	T356	R358Q	358	Missense	proximal	2	no	12.525	12.099	EPSD	COSMIC;CCLE	5.915	Down-regulation
CMGC_MAPK_p38_MAPK14_ST	P06400	RB1	Q16539	MAPK14	T356	N361Y	361	Missense	distal	5	no	12.525	12.582	EPSD	COSMIC	5.915	Up-regulation
CMGC_MAPK_p38_MAPK14_ST	P06400	RB1	Q16539	MAPK14	T373	P370S	370	Missense	distal	-3	no	8.453	9.216	EPSD	COSMIC	5.915	Up-regulation
CMGC_MAPK_p38_MAPK14_ST	P06400	RB1	Q16539	MAPK14	T373	P374L	374	Missense	proximal	1	no	8.453	0.402	EPSD	COSMIC	5.915	Loss
CMGC_MAPK_p38_MAPK14_ST	P06400	RB1	Q16539	MAPK14	T373	N367D	367	Missense	distal	-6	no	8.453	8.127	EPSD	COSMIC	5.915	Down-regulation
CMGC_MAPK_p38_MAPK14_ST	P06400	RB1	Q16539	MAPK14	T373	P370L	370	Missense	distal	-3	no	8.453	7.485	EPSD	COSMIC	5.915	Down-regulation
CMGC_MAPK_p38_MAPK14_ST	P06400	RB1	Q16539	MAPK14	S567	W563C	563	Missense	distal	-4	no	7.930	7.751	EPSD;PhosphoSitePlus	COSMIC	5.915	Down-regulation
CMGC_MAPK_p38_MAPK14_ST	P06400	RB1	Q16539	MAPK14	S567	S560P	560	Missense	distal	-7	no	7.930	7.843	EPSD;PhosphoSitePlus	COSMIC	5.915	Down-regulation
CMGC_MAPK_p38_MAPK14_ST	P06400	RB1	Q16539	MAPK14	S567	L564V	564	Missense	distal	-3	no	7.930	7.748	EPSD;PhosphoSitePlus	COSMIC	5.915	Down-regulation
CMGC_MAPK_p38_MAPK14_ST	P06400	RB1	Q16539	MAPK14	S567	L572F	572	Missense	distal	5	no	7.930	7.436	EPSD;PhosphoSitePlus	COSMIC	5.915	Down-regulation
CMGC_MAPK_p38_MAPK14_ST	P06400	RB1	Q16539	MAPK14	S608	R611S	611	Missense	distal	3	no	11.823	11.795	EPSD	COSMIC	5.915	Down-regulation
CMGC_MAPK_p38_MAPK14_ST	P06400	RB1	Q16539	MAPK14	S608	S612P	612	Missense	distal	4	no	11.823	11.383	EPSD	COSMIC	5.915	Down-regulation
CMGC_MAPK_p38_MAPK14_ST	P06400	RB1	Q16539	MAPK14	S608	Y606C	606	Missense	proximal	-2	no	11.823	10.685	EPSD	COSMIC	5.915	Down-regulation
CMGC_MAPK_p38_MAPK14_ST	P06400	RB1	Q16539	MAPK14	S608	P609S	609	Missense	proximal	1	no	11.823	4.539	EPSD	COSMIC	5.915	Loss
CMGC_MAPK_p38_MAPK14_ST	P06400	RB1	Q16539	MAPK14	S608	M605T	605	Missense	distal	-3	no	11.823	12.928	EPSD	COSMIC	5.915	Up-regulation
CMGC_MAPK_p38_MAPK14_ST	P06400	RB1	Q16539	MAPK14	S608	L607V	607	Missense	proximal	-1	no	11.823	11.760	EPSD	COSMIC	5.915	Down-regulation
CMGC_MAPK_p38_MAPK14_ST	P06400	RB1	Q16539	MAPK14	S608	L607I	607	Missense	proximal	-1	no	11.823	11.522	EPSD	COSMIC	5.915	Down-regulation
CMGC_MAPK_p38_MAPK14_ST	P06400	RB1	Q16539	MAPK14	S612	R611S	611	Missense	proximal	-1	no	8.447	8.555	EPSD	COSMIC	5.915	Up-regulation
CMGC_MAPK_p38_MAPK14_ST	P06400	RB1	Q16539	MAPK14	S612	S612P	612	Missense	central	0	yes	8.447	0.000	EPSD	COSMIC	5.915	Loss
CMGC_MAPK_p38_MAPK14_ST	P06400	RB1	Q16539	MAPK14	S612	Y606C	606	Missense	distal	-6	no	8.447	7.921	EPSD	COSMIC	5.915	Down-regulation
CMGC_MAPK_p38_MAPK14_ST	P06400	RB1	Q16539	MAPK14	S612	P609S	609	Missense	distal	-3	no	8.447	9.211	EPSD	COSMIC	5.915	Up-regulation
CMGC_MAPK_p38_MAPK14_ST	P06400	RB1	Q16539	MAPK14	S612	M605T	605	Missense	distal	-7	no	8.447	8.393	EPSD	COSMIC	5.915	Down-regulation
CMGC_MAPK_p38_MAPK14_ST	P06400	RB1	Q16539	MAPK14	S612	L607V	607	Missense	distal	-5	no	8.447	8.322	EPSD	COSMIC	5.915	Down-regulation
CMGC_MAPK_p38_MAPK14_ST	P06400	RB1	Q16539	MAPK14	S612	L607I	607	Missense	distal	-5	no	8.447	8.118	EPSD	COSMIC	5.915	Down-regulation
CMGC_MAPK_p38_MAPK14_ST	P06400	RB1	Q16539	MAPK14	T620	R621P	621	Missense	proximal	1	no	2.670	10.605	EPSD	COSMIC	5.915	Gain
CMGC_MAPK_p38_MAPK14_ST	P06400	RB1	Q16539	MAPK14	S624	T625A	625	Missense	proximal	1	no	4.935	6.069	EPSD	COSMIC	5.915	Gain
CMGC_MAPK_p38_MAPK14_ST	P06400	RB1	Q16539	MAPK14	T633	S634P	634	Missense	proximal	1	no	0.533	7.817	EPSD	COSMIC	5.915	Gain
CMGC_MAPK_p38_MAPK14_ST	P06400	RB1	Q16539	MAPK14	S780	P776R	776	Missense	distal	-4	no	7.541	7.464	EPSD	COSMIC	5.915	Down-regulation
CMGC_MAPK_p38_MAPK14_ST	P06400	RB1	Q16539	MAPK14	S780	H784Y	784	Missense	distal	4	no	7.541	7.604	EPSD	COSMIC	5.915	Up-regulation
CMGC_MAPK_p38_MAPK14_ST	P06400	RB1	Q16539	MAPK14	S780	P777S	777	Missense	distal	-3	no	7.541	8.305	EPSD	COSMIC	5.915	Up-regulation
CMGC_MAPK_p38_MAPK14_ST	P06400	RB1	Q16539	MAPK14	S780	P786S	786	Missense	distal	6	no	7.541	7.529	EPSD	COSMIC	5.915	Down-regulation
CMGC_MAPK_p38_MAPK14_ST	P06400	RB1	Q16539	MAPK14	S780	S773F	773	Missense	distal	-7	no	7.541	6.795	EPSD	COSMIC	5.915	Down-regulation
CMGC_MAPK_p38_MAPK14_ST	P06400	RB1	Q16539	MAPK14	S788	S795L	795	Missense	distal	7	no	8.319	7.934	EPSD	COSMIC	5.915	Down-regulation
CMGC_MAPK_p38_MAPK14_ST	P06400	RB1	Q16539	MAPK14	S788	H784Y	784	Missense	distal	-4	no	8.319	8.093	EPSD	COSMIC	5.915	Down-regulation
CMGC_MAPK_p38_MAPK14_ST	P06400	RB1	Q16539	MAPK14	S788	S794I	794	Missense	distal	6	no	8.319	8.108	EPSD	COSMIC	5.915	Down-regulation
CMGC_MAPK_p38_MAPK14_ST	P06400	RB1	Q16539	MAPK14	S788	P786S	786	Missense	proximal	-2	no	8.319	7.831	EPSD	COSMIC	5.915	Down-regulation
CMGC_MAPK_p38_MAPK14_ST	P06400	RB1	Q16539	MAPK14	S788	P793S	793	Missense	distal	5	no	8.319	8.770	EPSD	COSMIC;CCLE	5.915	Up-regulation
CMGC_MAPK_p38_MAPK14_ST	P06400	RB1	Q16539	MAPK14	S795	S795L	795	Missense	central	0	yes	7.500	0.000	EPSD	COSMIC	5.915	Loss
CMGC_MAPK_p38_MAPK14_ST	P06400	RB1	Q16539	MAPK14	S795	G802R	802	Missense	distal	7	no	7.500	7.678	EPSD	COSMIC	5.915	Up-regulation
CMGC_MAPK_p38_MAPK14_ST	P06400	RB1	Q16539	MAPK14	S795	R798Q	798	Missense	distal	3	no	7.500	7.541	EPSD	COSMIC;GDSC;CCLE	5.915	Up-regulation
CMGC_MAPK_p38_MAPK14_ST	P06400	RB1	Q16539	MAPK14	S795	S794I	794	Missense	proximal	-1	no	7.500	7.478	EPSD	COSMIC	5.915	Down-regulation
CMGC_MAPK_p38_MAPK14_ST	P06400	RB1	Q16539	MAPK14	S795	G801A	801	Missense	distal	6	no	7.500	7.434	EPSD	COSMIC	5.915	Down-regulation
CMGC_MAPK_p38_MAPK14_ST	P06400	RB1	Q16539	MAPK14	S795	P793S	793	Missense	proximal	-2	no	7.500	7.011	EPSD	COSMIC;CCLE	5.915	Down-regulation
CMGC_MAPK_p38_MAPK14_ST	P06400	RB1	Q16539	MAPK14	S807	G802R	802	Missense	distal	-5	no	12.132	11.970	EPSD	COSMIC	5.915	Down-regulation
CMGC_MAPK_p38_MAPK14_ST	P06400	RB1	Q16539	MAPK14	S807	K814T	814	Missense	distal	7	no	12.132	12.301	EPSD	COSMIC	5.915	Up-regulation
CMGC_MAPK_p38_MAPK14_ST	P06400	RB1	Q16539	MAPK14	S807	G801A	801	Missense	distal	-6	no	12.132	12.070	EPSD	COSMIC	5.915	Down-regulation
CMGC_MAPK_p38_MAPK14_ST	P06400	RB1	Q16539	MAPK14	S811	G818S	818	Missense	distal	7	no	11.148	11.292	EPSD	COSMIC	5.915	Up-regulation
CMGC_MAPK_p38_MAPK14_ST	P06400	RB1	Q16539	MAPK14	S811	G818C	818	Missense	distal	7	no	11.148	10.727	EPSD	COSMIC	5.915	Down-regulation
CMGC_MAPK_p38_MAPK14_ST	P06400	RB1	Q16539	MAPK14	S811	K814T	814	Missense	distal	3	no	11.148	11.118	EPSD	COSMIC	5.915	Down-regulation
CMGC_MAPK_p38_MAPK14_ST	P06400	RB1	Q16539	MAPK14	T821	G818S	818	Missense	distal	-3	no	8.094	9.031	EPSD	COSMIC	5.915	Up-regulation
CMGC_MAPK_p38_MAPK14_ST	P06400	RB1	Q16539	MAPK14	T821	P822S	822	Missense	proximal	1	no	8.094	0.810	EPSD	COSMIC	5.915	Loss
CMGC_MAPK_p38_MAPK14_ST	P06400	RB1	Q16539	MAPK14	T821	G818C	818	Missense	distal	-3	no	8.094	7.348	EPSD	COSMIC	5.915	Down-regulation
CMGC_MAPK_p38_MAPK14_ST	P06400	RB1	Q16539	MAPK14	T821	K814T	814	Missense	distal	-7	no	8.094	7.927	EPSD	COSMIC	5.915	Down-regulation
CMGC_MAPK_p38_MAPK14_ST	P06400	RB1	Q16539	MAPK14	T826	S829L	829	Missense	distal	3	no	10.042	10.116	EPSD	COSMIC	5.915	Up-regulation
CMGC_MAPK_p38_MAPK14_ST	P06400	RB1	Q16539	MAPK14	T826	P822S	822	Missense	distal	-4	no	10.042	9.955	EPSD	COSMIC	5.915	Down-regulation
CMGC_MAPK_p38_MAPK14_ST	P06400	RB1	Q16539	MAPK14	T922	D918N	918	Missense	distal	-4	no	8.007	7.586	EPSD	COSMIC	5.915	Down-regulation
CMGC_MAPK_p38_MAPK14_ST	P17181	IFNAR1	Q16539	MAPK14	S532	S528T	528	Missense	distal	-4	no	7.024	7.302	PhosphoSitePlus	COSMIC	5.915	Up-regulation
CMGC_MAPK_p38_MAPK14_ST	P17181	IFNAR1	Q16539	MAPK14	S532	S539Y	539	Missense	distal	7	no	7.024	7.067	PhosphoSitePlus	COSMIC	5.915	Up-regulation
CMGC_MAPK_p38_MAPK14_ST	P40763	STAT3	Q16539	MAPK14	S25	M28I	28	Missense	distal	3	no	7.291	7.350	EPSD	COSMIC	5.915	Up-regulation
CMGC_MAPK_p38_MAPK14_ST	P40763	STAT3	Q16539	MAPK14	S25	L18V	18	Missense	distal	-7	no	7.291	6.867	EPSD	COSMIC	5.915	Down-regulation
CMGC_MAPK_p38_MAPK14_ST	P40763	STAT3	Q16539	MAPK14	S25	P27S	27	Missense	proximal	2	no	7.291	7.668	EPSD	COSMIC	5.915	Up-regulation
CMGC_MAPK_p38_MAPK14_ST	P40763	STAT3	Q16539	MAPK14	S25	L18H	18	Missense	distal	-7	no	7.291	7.108	EPSD	COSMIC	5.915	Down-regulation
CMGC_MAPK_p38_MAPK14_ST	P40763	STAT3	Q16539	MAPK14	S25	L18P	18	Missense	distal	-7	no	7.291	7.484	EPSD	COSMIC	5.915	Up-regulation
CMGC_MAPK_p38_MAPK14_ST	P40763	STAT3	Q16539	MAPK14	T412	L413P	413	Missense	proximal	1	no	0.159	8.209	EPSD	COSMIC	5.915	Gain
CMGC_MAPK_p38_MAPK14_ST	P40763	STAT3	Q16539	MAPK14	T440	H447Y	447	Missense	distal	7	no	6.042	6.584	EPSD	COSMIC	5.915	Up-regulation
CMGC_MAPK_p38_MAPK14_ST	P40763	STAT3	Q16539	MAPK14	T440	T433I	433	Missense	distal	-7	no	6.042	5.691	EPSD	COSMIC	5.915	Loss
CMGC_MAPK_p38_MAPK14_ST	P40763	STAT3	Q16539	MAPK14	S691	D698N	698	Missense	distal	7	no	7.052	6.730	EPSD	COSMIC	5.915	Down-regulation
CMGC_MAPK_p38_MAPK14_ST	P40763	STAT3	Q16539	MAPK14	S691	G684R	684	Missense	distal	-7	no	7.052	6.950	EPSD	COSMIC	5.915	Down-regulation
CMGC_MAPK_p38_MAPK14_ST	P40763	STAT3	Q16539	MAPK14	T714	I711L	711	Missense	distal	-3	no	8.540	8.881	EPSD	COSMIC	5.915	Up-regulation
CMGC_MAPK_p38_MAPK14_ST	P40763	STAT3	Q16539	MAPK14	S727	D723N	723	Missense	distal	-4	no	13.540	13.119	PhosphoSitePlus	COSMIC	5.915	Down-regulation
CMGC_MAPK_p38_MAPK14_ST	O43684	BUB3	Q16539	MAPK14	S23	L30M	30	Missense	distal	7	no	7.894	8.149	EPSD	COSMIC	5.915	Up-regulation
CMGC_MAPK_p38_MAPK14_ST	O43684	BUB3	Q16539	MAPK14	T127	A131V	131	Missense	distal	4	no	12.145	11.711	EPSD	COSMIC	5.915	Down-regulation
CMGC_MAPK_p38_MAPK14_ST	P10415	BCL2	Q16539	MAPK14	T56	F49C	49	Missense	distal	-7	no	9.545	9.730	PhosphoSitePlus;EPSD	COSMIC	5.915	Up-regulation
CMGC_MAPK_p38_MAPK14_ST	P10415	BCL2	Q16539	MAPK14	T56	S51Y	51	Missense	distal	-5	no	9.545	9.993	PhosphoSitePlus;EPSD	COSMIC	5.915	Up-regulation
CMGC_MAPK_p38_MAPK14_ST	P10415	BCL2	Q16539	MAPK14	T56	P57S	57	Missense	proximal	1	no	9.545	2.261	PhosphoSitePlus;EPSD	COSMIC	5.915	Loss
CMGC_MAPK_p38_MAPK14_ST	P10415	BCL2	Q16539	MAPK14	T56	F49S	49	Missense	distal	-7	no	9.545	10.291	PhosphoSitePlus;EPSD	COSMIC	5.915	Up-regulation
CMGC_MAPK_p38_MAPK14_ST	P10415	BCL2	Q16539	MAPK14	T56	H58L	58	Missense	proximal	2	no	9.545	9.584	PhosphoSitePlus;EPSD	COSMIC	5.915	Up-regulation
CMGC_MAPK_p38_MAPK14_ST	P10415	BCL2	Q16539	MAPK14	T56	Q52P	52	Missense	distal	-4	no	9.545	9.254	PhosphoSitePlus;EPSD	COSMIC	5.915	Down-regulation
CMGC_MAPK_p38_MAPK14_ST	P10415	BCL2	Q16539	MAPK14	T56	S51P	51	Missense	distal	-5	no	9.545	9.993	PhosphoSitePlus;EPSD	COSMIC	5.915	Up-regulation
CMGC_MAPK_p38_MAPK14_ST	P10415	BCL2	Q16539	MAPK14	T56	S50P	50	Missense	distal	-6	no	9.545	8.938	PhosphoSitePlus;EPSD	COSMIC	5.915	Down-regulation
CMGC_MAPK_p38_MAPK14_ST	P10415	BCL2	Q16539	MAPK14	T56	H58R	58	Missense	proximal	2	no	9.545	9.928	PhosphoSitePlus;EPSD	COSMIC	5.915	Up-regulation
CMGC_MAPK_p38_MAPK14_ST	P10415	BCL2	Q16539	MAPK14	T56	A60G	60	Missense	distal	4	no	9.545	9.619	PhosphoSitePlus;EPSD	COSMIC	5.915	Up-regulation
CMGC_MAPK_p38_MAPK14_ST	P10415	BCL2	Q16539	MAPK14	T56	P57L	57	Missense	proximal	1	no	9.545	1.494	PhosphoSitePlus;EPSD	COSMIC	5.915	Loss
CMGC_MAPK_p38_MAPK14_ST	P10415	BCL2	Q16539	MAPK14	T56	A60D	60	Missense	distal	4	no	9.545	8.681	PhosphoSitePlus;EPSD	COSMIC	5.915	Down-regulation
CMGC_MAPK_p38_MAPK14_ST	P10415	BCL2	Q16539	MAPK14	T56	Q52H	52	Missense	distal	-4	no	9.545	9.388	PhosphoSitePlus;EPSD	COSMIC	5.915	Down-regulation
CMGC_MAPK_p38_MAPK14_ST	P10415	BCL2	Q16539	MAPK14	T56	P57A	57	Missense	proximal	1	no	9.545	3.226	PhosphoSitePlus;EPSD	COSMIC	5.915	Loss
CMGC_MAPK_p38_MAPK14_ST	P10415	BCL2	Q16539	MAPK14	S70	T74N	74	Missense	distal	4	no	12.013	11.758	EPSD	COSMIC	5.915	Down-regulation
CMGC_MAPK_p38_MAPK14_ST	P10415	BCL2	Q16539	MAPK14	S70	T69A	69	Missense	proximal	-1	no	12.013	11.957	EPSD	COSMIC	5.915	Down-regulation
CMGC_MAPK_p38_MAPK14_ST	P10415	BCL2	Q16539	MAPK14	S70	A67V	67	Missense	distal	-3	no	12.013	10.513	EPSD	COSMIC	5.915	Down-regulation
CMGC_MAPK_p38_MAPK14_ST	P10415	BCL2	Q16539	MAPK14	S70	P65S	65	Missense	distal	-5	no	12.013	11.565	EPSD	COSMIC	5.915	Down-regulation
CMGC_MAPK_p38_MAPK14_ST	P10415	BCL2	Q16539	MAPK14	S70	A76T	76	Missense	distal	6	no	12.013	11.996	EPSD	COSMIC	5.915	Down-regulation
CMGC_MAPK_p38_MAPK14_ST	P10415	BCL2	Q16539	MAPK14	S70	A77V	77	Missense	distal	7	no	12.013	11.904	EPSD	COSMIC	5.915	Down-regulation
CMGC_MAPK_p38_MAPK14_ST	P10415	BCL2	Q16539	MAPK14	S70	P71S	71	Missense	proximal	1	no	12.013	4.730	EPSD	COSMIC	5.915	Loss
CMGC_MAPK_p38_MAPK14_ST	P10415	BCL2	Q16539	MAPK14	S70	D64G	64	Missense	distal	-6	no	12.013	12.281	EPSD	COSMIC	5.915	Up-regulation
CMGC_MAPK_p38_MAPK14_ST	P10415	BCL2	Q16539	MAPK14	S70	A76S	76	Missense	distal	6	no	12.013	11.958	EPSD	COSMIC	5.915	Down-regulation
CMGC_MAPK_p38_MAPK14_ST	P10415	BCL2	Q16539	MAPK14	S70	T74A	74	Missense	distal	4	no	12.013	11.969	EPSD	COSMIC	5.915	Down-regulation
CMGC_MAPK_p38_MAPK14_ST	P10415	BCL2	Q16539	MAPK14	S70	T74I	74	Missense	distal	4	no	12.013	11.486	EPSD	COSMIC	5.915	Down-regulation
CMGC_MAPK_p38_MAPK14_ST	P10415	BCL2	Q16539	MAPK14	S70	T69P	69	Missense	proximal	-1	no	12.013	11.989	EPSD	COSMIC;CCLE	5.915	Down-regulation
CMGC_MAPK_p38_MAPK14_ST	P10415	BCL2	Q16539	MAPK14	S70	V66I	66	Missense	distal	-4	no	12.013	11.858	EPSD	COSMIC	5.915	Down-regulation
CMGC_MAPK_p38_MAPK14_ST	P10415	BCL2	Q16539	MAPK14	S70	P65Q	65	Missense	distal	-5	no	12.013	11.741	EPSD	COSMIC	5.915	Down-regulation
CMGC_MAPK_p38_MAPK14_ST	P10415	BCL2	Q16539	MAPK14	T74	T74N	74	Missense	central	0	yes	9.176	0.000	EPSD	COSMIC	5.915	Loss
CMGC_MAPK_p38_MAPK14_ST	P10415	BCL2	Q16539	MAPK14	T74	T69A	69	Missense	distal	-5	no	9.176	8.847	EPSD	COSMIC	5.915	Down-regulation
CMGC_MAPK_p38_MAPK14_ST	P10415	BCL2	Q16539	MAPK14	T74	A67V	67	Missense	distal	-7	no	9.176	8.357	EPSD	COSMIC	5.915	Down-regulation
CMGC_MAPK_p38_MAPK14_ST	P10415	BCL2	Q16539	MAPK14	T74	A76T	76	Missense	proximal	2	no	9.176	9.204	EPSD	COSMIC	5.915	Up-regulation
CMGC_MAPK_p38_MAPK14_ST	P10415	BCL2	Q16539	MAPK14	T74	A77V	77	Missense	distal	3	no	9.176	9.203	EPSD	COSMIC	5.915	Up-regulation
CMGC_MAPK_p38_MAPK14_ST	P10415	BCL2	Q16539	MAPK14	T74	P71S	71	Missense	distal	-3	no	9.176	9.939	EPSD	COSMIC	5.915	Up-regulation
CMGC_MAPK_p38_MAPK14_ST	P10415	BCL2	Q16539	MAPK14	T74	A76S	76	Missense	proximal	2	no	9.176	9.439	EPSD	COSMIC	5.915	Up-regulation
CMGC_MAPK_p38_MAPK14_ST	P10415	BCL2	Q16539	MAPK14	T74	T74A	74	Missense	central	0	yes	9.176	0.000	EPSD	COSMIC	5.915	Loss
CMGC_MAPK_p38_MAPK14_ST	P10415	BCL2	Q16539	MAPK14	T74	A80V	80	Missense	distal	6	no	9.176	8.880	EPSD	COSMIC	5.915	Down-regulation
CMGC_MAPK_p38_MAPK14_ST	P10415	BCL2	Q16539	MAPK14	T74	T74I	74	Missense	central	0	yes	9.176	0.000	EPSD	COSMIC	5.915	Loss
CMGC_MAPK_p38_MAPK14_ST	P10415	BCL2	Q16539	MAPK14	T74	T69P	69	Missense	distal	-5	no	9.176	9.183	EPSD	COSMIC;CCLE	5.915	Up-regulation
CMGC_MAPK_p38_MAPK14_ST	P10415	BCL2	Q16539	MAPK14	S87	L86F	86	Missense	proximal	-1	no	11.962	11.926	EPSD;PhosphoSitePlus	COSMIC	5.915	Down-regulation
CMGC_MAPK_p38_MAPK14_ST	P10415	BCL2	Q16539	MAPK14	S87	A85V	85	Missense	proximal	-2	no	11.962	11.547	EPSD;PhosphoSitePlus	COSMIC	5.915	Down-regulation
CMGC_MAPK_p38_MAPK14_ST	P10415	BCL2	Q16539	MAPK14	S87	P91S	91	Missense	distal	4	no	11.962	12.401	EPSD;PhosphoSitePlus	COSMIC;GDSC;CCLE	5.915	Up-regulation
CMGC_MAPK_p38_MAPK14_ST	P10415	BCL2	Q16539	MAPK14	S87	G83E	83	Missense	distal	-4	no	11.962	11.665	EPSD;PhosphoSitePlus	COSMIC	5.915	Down-regulation
CMGC_MAPK_p38_MAPK14_ST	P10415	BCL2	Q16539	MAPK14	S87	P91A	91	Missense	distal	4	no	11.962	12.095	EPSD;PhosphoSitePlus	COSMIC	5.915	Up-regulation
CMGC_MAPK_p38_MAPK14_ST	P10415	BCL2	Q16539	MAPK14	S87	P90T	90	Missense	distal	3	no	11.962	11.935	EPSD;PhosphoSitePlus	COSMIC	5.915	Down-regulation
CMGC_MAPK_p38_MAPK14_ST	P10415	BCL2	Q16539	MAPK14	S87	H94Y	94	Missense	distal	7	no	11.962	12.504	EPSD;PhosphoSitePlus	COSMIC	5.915	Up-regulation
CMGC_MAPK_p38_MAPK14_ST	P10415	BCL2	Q16539	MAPK14	S87	A85T	85	Missense	proximal	-2	no	11.962	11.905	EPSD;PhosphoSitePlus	COSMIC	5.915	Down-regulation
CMGC_MAPK_p38_MAPK14_ST	P10415	BCL2	Q16539	MAPK14	S87	V93L	93	Missense	distal	6	no	11.962	12.075	EPSD;PhosphoSitePlus	COSMIC	5.915	Up-regulation
CMGC_MAPK_p38_MAPK14_ST	P10415	BCL2	Q16539	MAPK14	S87	P91L	91	Missense	distal	4	no	11.962	11.323	EPSD;PhosphoSitePlus	COSMIC	5.915	Down-regulation
CMGC_MAPK_p38_MAPK14_ST	P10415	BCL2	Q16539	MAPK14	S87	S87N	87	Missense	central	0	yes	11.962	0.000	EPSD;PhosphoSitePlus	COSMIC	5.915	Loss
CMGC_MAPK_p38_MAPK14_ST	P10415	BCL2	Q16539	MAPK14	S87	A80V	80	Missense	distal	-7	no	11.962	11.144	EPSD;PhosphoSitePlus	COSMIC	5.915	Down-regulation
CMGC_MAPK_p38_MAPK14_ST	P30279	CCND2	Q16539	MAPK14	S269	K270M	270	Missense	proximal	1	no	4.432	6.276	EPSD	COSMIC	5.915	Gain
CMGC_MAPK_p38_MAPK14_ST	P30279	CCND2	Q16539	MAPK14	S271	G268R	268	Missense	distal	-3	no	4.678	6.128	EPSD	COSMIC	5.915	Gain
CMGC_MAPK_p38_MAPK14_ST	P30279	CCND2	Q16539	MAPK14	T280	P281A	281	Missense	proximal	1	no	9.625	3.307	PhosphoSitePlus	COSMIC;GDSC;CCLE	5.915	Loss
CMGC_MAPK_p38_MAPK14_ST	P30279	CCND2	Q16539	MAPK14	T280	D276E	276	Missense	distal	-4	no	9.625	8.833	PhosphoSitePlus	COSMIC	5.915	Down-regulation
CMGC_MAPK_p38_MAPK14_ST	P30279	CCND2	Q16539	MAPK14	T280	P281L	281	Missense	proximal	1	no	9.625	1.575	PhosphoSitePlus	COSMIC	5.915	Loss
CMGC_MAPK_p38_MAPK14_ST	P30279	CCND2	Q16539	MAPK14	T280	D283E	283	Missense	distal	3	no	9.625	9.570	PhosphoSitePlus	COSMIC	5.915	Down-regulation
CMGC_MAPK_p38_MAPK14_ST	P30279	CCND2	Q16539	MAPK14	T280	V284M	284	Missense	distal	4	no	9.625	10.041	PhosphoSitePlus	COSMIC;GDSC;CCLE	5.915	Up-regulation
CMGC_MAPK_p38_MAPK14_ST	P30279	CCND2	Q16539	MAPK14	T280	P281N	281	Missense	proximal	1	no	9.625	1.822	PhosphoSitePlus	COSMIC	5.915	Loss
CMGC_MAPK_p38_MAPK14_ST	P13473	LAMP2	Q16539	MAPK14	T211	E216K	216	Missense	distal	5	no	11.924	11.357	PhosphoSitePlus;EPSD	COSMIC	5.915	Down-regulation
CMGC_MAPK_p38_MAPK14_ST	P13473	LAMP2	Q16539	MAPK14	T213	E216K	216	Missense	distal	3	no	12.977	13.025	EPSD;PhosphoSitePlus	COSMIC	5.915	Up-regulation
CMGC_MAPK_p38_MAPK14_ST	P13473	LAMP2	Q16539	MAPK14	S276	L282I	282	Missense	distal	6	no	7.089	7.006	EPSD	COSMIC	5.915	Down-regulation
CMGC_MAPK_p38_MAPK14_ST	P13473	LAMP2	Q16539	MAPK14	S276	L272R	272	Missense	distal	-4	no	7.089	6.501	EPSD	COSMIC	5.915	Down-regulation
CMGC_MAPK_p38_MAPK14_ST	P55273	CDKN2D	Q16539	MAPK14	S66	T72I	72	Missense	distal	6	no	11.408	11.159	PhosphoSitePlus	COSMIC	5.915	Down-regulation
CMGC_MAPK_p38_MAPK14_ST	P55273	CDKN2D	Q16539	MAPK14	S76	H79Y	79	Missense	distal	3	no	7.827	7.770	EPSD	COSMIC	5.915	Down-regulation
CMGC_MAPK_p38_MAPK14_ST	P55273	CDKN2D	Q16539	MAPK14	S76	T72I	72	Missense	distal	-4	no	7.827	7.717	EPSD	COSMIC	5.915	Down-regulation
CMGC_MAPK_p38_MAPK14_ST	P55273	CDKN2D	Q16539	MAPK14	S76	A81T	81	Missense	distal	5	no	7.827	8.300	EPSD	COSMIC	5.915	Up-regulation
CMGC_MAPK_p38_MAPK14_ST	P55273	CDKN2D	Q16539	MAPK14	T141	P142L	142	Missense	proximal	1	no	10.969	2.918	EPSD	COSMIC	5.915	Loss
CMGC_MAPK_p38_MAPK14_ST	P55273	CDKN2D	Q16539	MAPK14	T141	A146V	146	Missense	distal	5	no	10.969	10.950	EPSD	COSMIC	5.915	Down-regulation
CMGC_MAPK_p38_MAPK14_ST	P48436	SOX9	Q16539	MAPK14	S23	A21V	21	Missense	proximal	-2	no	12.129	11.715	EPSD	COSMIC	5.915	Down-regulation
CMGC_MAPK_p38_MAPK14_ST	P48436	SOX9	Q16539	MAPK14	S23	E28D	28	Missense	distal	5	no	12.129	11.623	EPSD	COSMIC	5.915	Down-regulation
CMGC_MAPK_p38_MAPK14_ST	P48436	SOX9	Q16539	MAPK14	S23	P24T	24	Missense	proximal	1	no	12.129	4.676	EPSD	COSMIC	5.915	Loss
CMGC_MAPK_p38_MAPK14_ST	P48436	SOX9	Q16539	MAPK14	S23	P22L	22	Missense	proximal	-1	no	12.129	12.315	EPSD	COSMIC	5.915	Up-regulation
CMGC_MAPK_p38_MAPK14_ST	P48436	SOX9	Q16539	MAPK14	S23	A21T	21	Missense	proximal	-2	no	12.129	12.072	EPSD	COSMIC	5.915	Down-regulation
CMGC_MAPK_p38_MAPK14_ST	P48436	SOX9	Q16539	MAPK14	S23	M26V	26	Missense	distal	3	no	12.129	12.134	EPSD	COSMIC	5.915	Up-regulation
CMGC_MAPK_p38_MAPK14_ST	P48436	SOX9	Q16539	MAPK14	S33	S39C	39	Missense	distal	6	no	11.945	11.670	EPSD	COSMIC	5.915	Down-regulation
CMGC_MAPK_p38_MAPK14_ST	P48436	SOX9	Q16539	MAPK14	S33	E28D	28	Missense	distal	-5	no	11.945	12.819	EPSD	COSMIC	5.915	Up-regulation
CMGC_MAPK_p38_MAPK14_ST	P48436	SOX9	Q16539	MAPK14	S33	P34T	34	Missense	proximal	1	no	11.945	4.491	EPSD	COSMIC	5.915	Loss
CMGC_MAPK_p38_MAPK14_ST	P48436	SOX9	Q16539	MAPK14	S33	S33L	33	Missense	central	0	yes	11.945	0.000	EPSD	COSMIC	5.915	Loss
CMGC_MAPK_p38_MAPK14_ST	P48436	SOX9	Q16539	MAPK14	S33	M26V	26	Missense	distal	-7	no	11.945	11.255	EPSD	COSMIC	5.915	Down-regulation
CMGC_MAPK_p38_MAPK14_ST	P48436	SOX9	Q16539	MAPK14	S33	A31G	31	Missense	proximal	-2	no	11.945	11.669	EPSD	COSMIC	5.915	Down-regulation
CMGC_MAPK_p38_MAPK14_ST	P48436	SOX9	Q16539	MAPK14	S33	G32C	32	Missense	proximal	-1	no	11.945	11.887	EPSD	COSMIC	5.915	Down-regulation
CMGC_MAPK_p38_MAPK14_ST	P48436	SOX9	Q16539	MAPK14	S33	P36Q	36	Missense	distal	3	no	11.945	11.973	EPSD	COSMIC	5.915	Up-regulation
CMGC_MAPK_p38_MAPK14_ST	P48436	SOX9	Q16539	MAPK14	T46	S41L	41	Missense	distal	-5	no	5.620	6.349	EPSD	COSMIC	5.915	Gain
CMGC_MAPK_p38_MAPK14_ST	P48436	SOX9	Q16539	MAPK14	S199	T193M	193	Missense	distal	-6	no	8.993	8.405	EPSD	COSMIC	5.915	Down-regulation
CMGC_MAPK_p38_MAPK14_ST	P48436	SOX9	Q16539	MAPK14	S199	A202T	202	Missense	distal	3	no	8.993	8.992	EPSD	COSMIC	5.915	Down-regulation
CMGC_MAPK_p38_MAPK14_ST	P48436	SOX9	Q16539	MAPK14	S199	T196A	196	Missense	distal	-3	no	8.993	8.898	EPSD	COSMIC	5.915	Down-regulation
CMGC_MAPK_p38_MAPK14_ST	P48436	SOX9	Q16539	MAPK14	S211	P212S	212	Missense	proximal	1	no	11.044	3.760	PhosphoSitePlus	COSMIC	5.915	Loss
CMGC_MAPK_p38_MAPK14_ST	P48436	SOX9	Q16539	MAPK14	S214	E220D	220	Missense	distal	6	no	7.938	7.837	EPSD	COSMIC	5.915	Down-regulation
CMGC_MAPK_p38_MAPK14_ST	P48436	SOX9	Q16539	MAPK14	S214	P212S	212	Missense	proximal	-2	no	7.938	7.449	EPSD	COSMIC	5.915	Down-regulation
CMGC_MAPK_p38_MAPK14_ST	P48436	SOX9	Q16539	MAPK14	S223	H227Y	227	Missense	distal	4	no	10.432	10.495	EPSD	COSMIC	5.915	Up-regulation
CMGC_MAPK_p38_MAPK14_ST	P48436	SOX9	Q16539	MAPK14	S223	S228L	228	Missense	distal	5	no	10.432	9.485	EPSD	COSMIC	5.915	Down-regulation
CMGC_MAPK_p38_MAPK14_ST	P48436	SOX9	Q16539	MAPK14	S223	G229R	229	Missense	distal	6	no	10.432	10.311	EPSD	COSMIC	5.915	Down-regulation
CMGC_MAPK_p38_MAPK14_ST	P48436	SOX9	Q16539	MAPK14	S223	E220D	220	Missense	distal	-3	no	10.432	10.226	EPSD	COSMIC	5.915	Down-regulation
CMGC_MAPK_p38_MAPK14_ST	P48436	SOX9	Q16539	MAPK14	T236	P235R	235	Missense	proximal	-1	no	11.834	11.634	EPSD	COSMIC	5.915	Down-regulation
CMGC_MAPK_p38_MAPK14_ST	P48436	SOX9	Q16539	MAPK14	T236	P235T	235	Missense	proximal	-1	no	11.834	11.858	EPSD	COSMIC	5.915	Up-regulation
CMGC_MAPK_p38_MAPK14_ST	P48436	SOX9	Q16539	MAPK14	T236	P237L	237	Missense	proximal	1	no	11.834	3.784	EPSD	COSMIC	5.915	Loss
CMGC_MAPK_p38_MAPK14_ST	P48436	SOX9	Q16539	MAPK14	T236	G229R	229	Missense	distal	-7	no	11.834	11.733	EPSD	COSMIC	5.915	Down-regulation
CMGC_MAPK_p38_MAPK14_ST	P48436	SOX9	Q16539	MAPK14	T236	G233S	233	Missense	distal	-3	no	11.834	12.772	EPSD	COSMIC	5.915	Up-regulation
CMGC_MAPK_p38_MAPK14_ST	P48436	SOX9	Q16539	MAPK14	T240	P235R	235	Missense	distal	-5	no	9.073	8.843	EPSD	COSMIC	5.915	Down-regulation
CMGC_MAPK_p38_MAPK14_ST	P48436	SOX9	Q16539	MAPK14	T240	P235T	235	Missense	distal	-5	no	9.073	9.065	EPSD	COSMIC	5.915	Down-regulation
CMGC_MAPK_p38_MAPK14_ST	P48436	SOX9	Q16539	MAPK14	T240	P237L	237	Missense	distal	-3	no	9.073	8.105	EPSD	COSMIC	5.915	Down-regulation
CMGC_MAPK_p38_MAPK14_ST	P48436	SOX9	Q16539	MAPK14	T240	G233S	233	Missense	distal	-7	no	9.073	9.140	EPSD	COSMIC	5.915	Up-regulation
CMGC_MAPK_p38_MAPK14_ST	P48436	SOX9	Q16539	MAPK14	S414	S421N	421	Missense	distal	7	no	9.332	9.034	EPSD	COSMIC	5.915	Down-regulation
CMGC_MAPK_p38_MAPK14_ST	P48436	SOX9	Q16539	MAPK14	S414	Q416P	416	Missense	proximal	2	no	9.332	9.527	EPSD	COSMIC	5.915	Up-regulation
CMGC_MAPK_p38_MAPK14_ST	P48436	SOX9	Q16539	MAPK14	S414	A419S	419	Missense	distal	5	no	9.332	9.971	EPSD	COSMIC	5.915	Up-regulation
CMGC_MAPK_p38_MAPK14_ST	P48436	SOX9	Q16539	MAPK14	S414	A419T	419	Missense	distal	5	no	9.332	9.805	EPSD	COSMIC	5.915	Up-regulation
CMGC_MAPK_p38_MAPK14_ST	P48436	SOX9	Q16539	MAPK14	S494	E499K	499	Missense	distal	5	no	8.400	7.833	EPSD	COSMIC	5.915	Down-regulation
CMGC_MAPK_p38_MAPK14_ST	P48436	SOX9	Q16539	MAPK14	S494	P495L	495	Missense	proximal	1	no	8.400	0.349	EPSD	COSMIC	5.915	Loss
CMGC_MAPK_p38_MAPK14_ST	P48436	SOX9	Q16539	MAPK14	S494	P487L	487	Missense	distal	-7	no	8.400	8.206	EPSD	COSMIC	5.915	Down-regulation
CMGC_MAPK_p38_MAPK14_ST	P48436	SOX9	Q16539	MAPK14	S494	H493Q	493	Missense	proximal	-1	no	8.400	8.333	EPSD	COSMIC	5.915	Down-regulation
CMGC_MAPK_p38_MAPK14_ST	Q8TE85	GRHL3	Q16539	MAPK14	S24	K22T	22	Missense	proximal	-2	no	5.494	6.066	EPSD	COSMIC	5.915	Gain
CMGC_MAPK_p38_MAPK14_ST	Q8TE85	GRHL3	Q16539	MAPK14	S105	T101I	101	Missense	distal	-4	no	10.630	10.520	EPSD	COSMIC;CCLE	5.915	Down-regulation
CMGC_MAPK_p38_MAPK14_ST	Q8TE85	GRHL3	Q16539	MAPK14	S105	H108N	108	Missense	distal	3	no	10.630	10.576	EPSD	COSMIC	5.915	Down-regulation
CMGC_MAPK_p38_MAPK14_ST	Q8TE85	GRHL3	Q16539	MAPK14	S215	E222G	222	Missense	distal	7	no	9.238	8.877	EPSD	COSMIC	5.915	Down-regulation
CMGC_MAPK_p38_MAPK14_ST	Q8TE85	GRHL3	Q16539	MAPK14	S215	P221L	221	Missense	distal	6	no	9.238	9.099	EPSD	COSMIC	5.915	Down-regulation
CMGC_MAPK_p38_MAPK14_ST	Q8TE85	GRHL3	Q16539	MAPK14	T454	R447Q	447	Missense	distal	-7	no	7.761	7.668	PhosphoSitePlus	COSMIC	5.915	Down-regulation
CMGC_MAPK_p38_MAPK14_ST	Q8TE85	GRHL3	Q16539	MAPK14	T454	P461H	461	Missense	distal	7	no	7.761	7.484	PhosphoSitePlus	COSMIC	5.915	Down-regulation
CMGC_MAPK_p38_MAPK14_ST	Q8TE85	GRHL3	Q16539	MAPK14	S493	S493L	493	Missense	central	0	yes	14.036	0.000	EPSD	COSMIC	5.915	Loss
CMGC_MAPK_p38_MAPK14_ST	Q8TE85	GRHL3	Q16539	MAPK14	S493	E500G	500	Missense	distal	7	no	14.036	13.675	EPSD	COSMIC	5.915	Down-regulation
CMGC_MAPK_p38_MAPK14_ST	Q8TE85	GRHL3	Q16539	MAPK14	S493	L486P	486	Missense	distal	-7	no	14.036	14.229	EPSD	COSMIC	5.915	Up-regulation
CMGC_MAPK_p38_MAPK14_ST	Q06330	RBPJ	Q16539	MAPK14	S7	P13S	13	Missense	distal	6	no	13.829	13.817	EPSD	COSMIC	5.915	Down-regulation
CMGC_MAPK_p38_MAPK14_ST	Q06330	RBPJ	Q16539	MAPK14	S18	R25L	25	Missense	distal	7	no	9.580	9.161	EPSD	COSMIC	5.915	Down-regulation
CMGC_MAPK_p38_MAPK14_ST	Q06330	RBPJ	Q16539	MAPK14	S18	P13S	13	Missense	distal	-5	no	9.580	9.132	EPSD	COSMIC	5.915	Down-regulation
CMGC_MAPK_p38_MAPK14_ST	Q06330	RBPJ	Q16539	MAPK14	S195	T197R	197	Missense	proximal	2	no	7.443	7.533	EPSD	COSMIC	5.915	Up-regulation
CMGC_MAPK_p38_MAPK14_ST	Q06330	RBPJ	Q16539	MAPK14	S195	R192Q	192	Missense	distal	-3	no	7.443	5.663	EPSD	COSMIC	5.915	Loss
CMGC_MAPK_p38_MAPK14_ST	Q06330	RBPJ	Q16539	MAPK14	S195	S199N	199	Missense	distal	4	no	7.443	6.926	EPSD	COSMIC	5.915	Down-regulation
CMGC_MAPK_p38_MAPK14_ST	Q06330	RBPJ	Q16539	MAPK14	T445	R451Q	451	Missense	distal	6	no	10.153	10.165	EPSD	COSMIC	5.915	Up-regulation
CMGC_MAPK_p38_MAPK14_ST	Q06330	RBPJ	Q16539	MAPK14	T445	E447K	447	Missense	proximal	2	no	10.153	9.839	EPSD	COSMIC	5.915	Down-regulation
CMGC_MAPK_p38_MAPK14_ST	Q9C026	TRIM9	Q16539	MAPK14	T41	S46Y	46	Missense	distal	5	no	12.387	12.108	EPSD	COSMIC	5.915	Down-regulation
CMGC_MAPK_p38_MAPK14_ST	Q9C026	TRIM9	Q16539	MAPK14	T41	T41A	41	Missense	central	0	yes	12.387	0.000	EPSD	COSMIC	5.915	Loss
CMGC_MAPK_p38_MAPK14_ST	Q9C026	TRIM9	Q16539	MAPK14	T41	L38P	38	Missense	distal	-3	no	12.387	13.355	EPSD	COSMIC	5.915	Up-regulation
CMGC_MAPK_p38_MAPK14_ST	Q9C026	TRIM9	Q16539	MAPK14	S46	S46Y	46	Missense	central	0	yes	10.278	0.000	EPSD	COSMIC	5.915	Loss
CMGC_MAPK_p38_MAPK14_ST	Q9C026	TRIM9	Q16539	MAPK14	S46	T41A	41	Missense	distal	-5	no	10.278	9.949	EPSD	COSMIC	5.915	Down-regulation
CMGC_MAPK_p38_MAPK14_ST	Q9C026	TRIM9	Q16539	MAPK14	T406	G403S	403	Missense	distal	-3	no	10.274	11.212	EPSD	COSMIC	5.915	Up-regulation
CMGC_MAPK_p38_MAPK14_ST	Q9C026	TRIM9	Q16539	MAPK14	T406	G401D	401	Missense	distal	-5	no	10.274	10.516	EPSD	COSMIC	5.915	Up-regulation
CMGC_MAPK_p38_MAPK14_ST	Q9C026	TRIM9	Q16539	MAPK14	T406	P407T	407	Missense	proximal	1	no	10.274	2.821	EPSD	COSMIC	5.915	Loss
CMGC_MAPK_p38_MAPK14_ST	Q9C026	TRIM9	Q16539	MAPK14	S625	R624W	624	Missense	proximal	-1	no	6.011	6.299	EPSD	COSMIC	5.915	Up-regulation
CMGC_MAPK_p38_MAPK14_ST	Q9C026	TRIM9	Q16539	MAPK14	S625	S625W	625	Missense	central	0	yes	6.011	0.000	EPSD	COSMIC	5.915	Loss
CMGC_MAPK_p38_MAPK14_ST	Q07817	BCL2L1	Q16539	MAPK14	S62	A64T	64	Missense	proximal	2	no	13.524	13.552	PhosphoSitePlus	COSMIC;GDSC;CCLE	5.915	Up-regulation
CMGC_MAPK_p38_MAPK14_ST	Q07817	BCL2L1	Q16539	MAPK14	S62	A60V	60	Missense	proximal	-2	no	13.524	13.109	PhosphoSitePlus	COSMIC;GDSC;CCLE	5.915	Down-regulation
CMGC_MAPK_p38_MAPK14_ST	Q07817	BCL2L1	Q16539	MAPK14	T115	L112V	112	Missense	distal	-3	no	10.425	10.244	EPSD	COSMIC	5.915	Down-regulation
CMGC_MAPK_p38_MAPK14_ST	Q07817	BCL2L1	Q16539	MAPK14	T115	G117E	117	Missense	proximal	2	no	10.425	10.619	EPSD	COSMIC	5.915	Up-regulation
CMGC_MAPK_p38_MAPK14_ST	Q07817	BCL2L1	Q16539	MAPK14	T115	H113Y	113	Missense	proximal	-2	no	10.425	12.206	EPSD	COSMIC	5.915	Up-regulation
CMGC_MAPK_p38_MAPK14_ST	Q07817	BCL2L1	Q16539	MAPK14	T115	A119V	119	Missense	distal	4	no	10.425	9.992	EPSD	COSMIC	5.915	Down-regulation
CMGC_MAPK_p38_MAPK14_ST	Q9H1K0	RBSN	Q16539	MAPK14	S204	S204G	204	Missense	central	0	yes	6.264	0.000	EPSD	COSMIC	5.915	Loss
CMGC_MAPK_p38_MAPK14_ST	Q9H1K0	RBSN	Q16539	MAPK14	S204	S206N	206	Missense	proximal	2	no	6.264	6.008	EPSD	COSMIC	5.915	Down-regulation
CMGC_MAPK_p38_MAPK14_ST	Q9H1K0	RBSN	Q16539	MAPK14	S215	P220S	220	Missense	distal	5	no	13.118	13.568	PhosphoSitePlus	COSMIC	5.915	Up-regulation
CMGC_MAPK_p38_MAPK14_ST	Q9H1K0	RBSN	Q16539	MAPK14	S215	P220L	220	Missense	distal	5	no	13.118	12.621	PhosphoSitePlus	COSMIC	5.915	Down-regulation
CMGC_MAPK_p38_MAPK14_ST	Q9H1K0	RBSN	Q16539	MAPK14	S219	P220S	220	Missense	proximal	1	no	9.704	2.421	EPSD	COSMIC	5.915	Loss
CMGC_MAPK_p38_MAPK14_ST	Q9H1K0	RBSN	Q16539	MAPK14	S219	P220L	220	Missense	proximal	1	no	9.704	1.654	EPSD	COSMIC	5.915	Loss
CMGC_MAPK_p38_MAPK14_ST	Q9H1K0	RBSN	Q16539	MAPK14	S219	V223D	223	Missense	distal	4	no	9.704	9.274	EPSD	COSMIC	5.915	Down-regulation
CMGC_MAPK_p38_MAPK14_ST	Q9H1K0	RBSN	Q16539	MAPK14	S541	S541F	541	Missense	central	0	yes	6.676	0.000	EPSD	COSMIC	5.915	Loss
CMGC_MAPK_p38_MAPK14_ST	Q9H1K0	RBSN	Q16539	MAPK14	S541	S548P	548	Missense	distal	7	no	6.676	6.454	EPSD	COSMIC	5.915	Down-regulation
CMGC_MAPK_p38_MAPK14_ST	Q9H1K0	RBSN	Q16539	MAPK14	S541	R538W	538	Missense	distal	-3	no	6.676	4.319	EPSD	COSMIC	5.915	Loss
CMGC_MAPK_p38_MAPK14_ST	Q9H1K0	RBSN	Q16539	MAPK14	S541	R547Q	547	Missense	distal	6	no	6.676	6.688	EPSD	COSMIC	5.915	Up-regulation
CMGC_MAPK_p38_MAPK14_ST	Q9H1K0	RBSN	Q16539	MAPK14	S541	A540T	540	Missense	proximal	-1	no	6.676	6.733	EPSD	COSMIC	5.915	Up-regulation
CMGC_MAPK_p38_MAPK14_ST	Q9H1K0	RBSN	Q16539	MAPK14	S541	R547W	547	Missense	distal	6	no	6.676	6.413	EPSD	COSMIC	5.915	Down-regulation
CMGC_MAPK_p38_MAPK14_ST	Q9H1K0	RBSN	Q16539	MAPK14	S541	R538L	538	Missense	distal	-3	no	6.676	4.432	EPSD	COSMIC	5.915	Loss
CMGC_MAPK_p38_MAPK14_ST	Q9H1K0	RBSN	Q16539	MAPK14	S541	E535V	535	Missense	distal	-6	no	6.676	5.816	EPSD	COSMIC	5.915	Loss
CMGC_MAPK_p38_MAPK14_ST	Q9H1K0	RBSN	Q16539	MAPK14	S578	P579T	579	Missense	proximal	1	no	11.616	4.162	EPSD	COSMIC	5.915	Loss
CMGC_MAPK_p38_MAPK14_ST	Q9H1K0	RBSN	Q16539	MAPK14	S578	L573F	573	Missense	distal	-5	no	11.616	11.671	EPSD	COSMIC	5.915	Up-regulation
CMGC_MAPK_p38_MAPK14_ST	Q9H1K0	RBSN	Q16539	MAPK14	S578	G576C	576	Missense	proximal	-2	no	11.616	10.930	EPSD	COSMIC	5.915	Down-regulation
CMGC_MAPK_p38_MAPK14_ST	Q9H1K0	RBSN	Q16539	MAPK14	S578	P581S	581	Missense	distal	3	no	11.616	11.575	EPSD	COSMIC;GDSC	5.915	Down-regulation
CMGC_MAPK_p38_MAPK14_ST	Q9H1K0	RBSN	Q16539	MAPK14	S578	A585T	585	Missense	distal	7	no	11.616	11.272	EPSD	COSMIC	5.915	Down-regulation
CMGC_MAPK_p38_MAPK14_ST	Q9H1K0	RBSN	Q16539	MAPK14	T588	L591P	591	Missense	distal	3	no	13.707	13.673	EPSD	COSMIC	5.915	Down-regulation
CMGC_MAPK_p38_MAPK14_ST	Q9H1K0	RBSN	Q16539	MAPK14	T588	P581S	581	Missense	distal	-7	no	13.707	13.794	EPSD	COSMIC;GDSC	5.915	Up-regulation
CMGC_MAPK_p38_MAPK14_ST	Q9H1K0	RBSN	Q16539	MAPK14	T588	A585T	585	Missense	distal	-3	no	13.707	13.802	EPSD	COSMIC	5.915	Up-regulation
CMGC_MAPK_p38_MAPK14_ST	Q9H1K0	RBSN	Q16539	MAPK14	T588	Q595E	595	Missense	distal	7	no	13.707	14.084	EPSD	COSMIC	5.915	Up-regulation
CMGC_MAPK_p38_MAPK14_ST	Q9H1K0	RBSN	Q16539	MAPK14	T588	K587N	587	Missense	proximal	-1	no	13.707	13.805	EPSD	COSMIC	5.915	Up-regulation
CMGC_MAPK_p38_MAPK14_ST	Q9H1K0	RBSN	Q16539	MAPK14	S590	L591P	591	Missense	proximal	1	no	3.730	11.780	EPSD	COSMIC	5.915	Gain
CMGC_MAPK_p38_MAPK14_ST	Q9H1K0	RBSN	Q16539	MAPK14	S684	P689L	689	Missense	distal	5	no	9.651	9.154	EPSD	COSMIC	5.915	Down-regulation
CMGC_MAPK_p38_MAPK14_ST	Q9H1K0	RBSN	Q16539	MAPK14	S684	P678S	678	Missense	distal	-6	no	9.651	10.257	EPSD	COSMIC	5.915	Up-regulation
CMGC_MAPK_p38_MAPK14_ST	Q9H1K0	RBSN	Q16539	MAPK14	S684	P689S	689	Missense	distal	5	no	9.651	10.101	EPSD	COSMIC	5.915	Up-regulation
CMGC_MAPK_p38_MAPK14_ST	Q9H1K0	RBSN	Q16539	MAPK14	S684	I680F	680	Missense	distal	-4	no	9.651	10.188	EPSD	COSMIC	5.915	Up-regulation
CMGC_MAPK_p38_MAPK14_ST	Q9H1K0	RBSN	Q16539	MAPK14	S724	E721D	721	Missense	distal	-3	no	6.808	6.602	EPSD	COSMIC	5.915	Down-regulation
CMGC_MAPK_p38_MAPK14_ST	Q02156	PRKCE	Q16539	MAPK14	T228	V232G	232	Missense	distal	4	no	9.657	10.165	EPSD	COSMIC	5.915	Up-regulation
CMGC_MAPK_p38_MAPK14_ST	Q02156	PRKCE	Q16539	MAPK14	T228	Q231H	231	Missense	distal	3	no	9.657	9.687	EPSD	COSMIC	5.915	Up-regulation
CMGC_MAPK_p38_MAPK14_ST	Q02156	PRKCE	Q16539	MAPK14	T228	K224N	224	Missense	distal	-4	no	9.657	9.804	EPSD	COSMIC	5.915	Up-regulation
CMGC_MAPK_p38_MAPK14_ST	Q02156	PRKCE	Q16539	MAPK14	T228	G233C	233	Missense	distal	5	no	9.657	8.732	EPSD	COSMIC	5.915	Down-regulation
CMGC_MAPK_p38_MAPK14_ST	Q02156	PRKCE	Q16539	MAPK14	S329	P330S	330	Missense	proximal	1	no	8.746	1.463	EPSD	COSMIC	5.915	Loss
CMGC_MAPK_p38_MAPK14_ST	Q02156	PRKCE	Q16539	MAPK14	S336	P330S	330	Missense	distal	-6	no	6.358	6.965	EPSD	COSMIC	5.915	Up-regulation
CMGC_MAPK_p38_MAPK14_ST	Q02156	PRKCE	Q16539	MAPK14	S337	P330S	330	Missense	distal	-7	no	12.983	13.070	EPSD	COSMIC	5.915	Up-regulation
CMGC_MAPK_p38_MAPK14_ST	Q02156	PRKCE	Q16539	MAPK14	S380	A378T	378	Missense	proximal	-2	no	6.788	6.731	EPSD	COSMIC	5.915	Down-regulation
CMGC_MAPK_p38_MAPK14_ST	Q02156	PRKCE	Q16539	MAPK14	S381	A378T	378	Missense	distal	-3	no	12.483	12.578	EPSD	COSMIC	5.915	Up-regulation
CMGC_MAPK_p38_MAPK14_ST	Q02156	PRKCE	Q16539	MAPK14	S388	P389T	389	Missense	proximal	1	no	11.577	4.124	EPSD	COSMIC	5.915	Loss
CMGC_MAPK_p38_MAPK14_ST	P23769	GATA2	Q16539	MAPK14	S73	A75G	75	Missense	proximal	2	no	8.380	8.415	EPSD	COSMIC	5.915	Up-regulation
CMGC_MAPK_p38_MAPK14_ST	P23769	GATA2	Q16539	MAPK14	S73	V70I	70	Missense	distal	-3	no	8.380	8.221	EPSD	COSMIC	5.915	Down-regulation
CMGC_MAPK_p38_MAPK14_ST	P23769	GATA2	Q16539	MAPK14	S73	A68E	68	Missense	distal	-5	no	8.380	8.017	EPSD	COSMIC	5.915	Down-regulation
CMGC_MAPK_p38_MAPK14_ST	P23769	GATA2	Q16539	MAPK14	S73	A68V	68	Missense	distal	-5	no	8.380	8.872	EPSD	COSMIC	5.915	Up-regulation
CMGC_MAPK_p38_MAPK14_ST	P23769	GATA2	Q16539	MAPK14	S73	S71F	71	Missense	proximal	-2	no	8.380	7.656	EPSD	COSMIC;GDSC;CCLE	5.915	Down-regulation
CMGC_MAPK_p38_MAPK14_ST	P23769	GATA2	Q16539	MAPK14	S119	S122F	122	Missense	distal	3	no	9.445	9.554	EPSD	COSMIC	5.915	Up-regulation
CMGC_MAPK_p38_MAPK14_ST	P23769	GATA2	Q16539	MAPK14	S119	S122T	122	Missense	distal	3	no	9.445	9.459	EPSD	COSMIC	5.915	Up-regulation
CMGC_MAPK_p38_MAPK14_ST	P23769	GATA2	Q16539	MAPK14	S119	P125T	125	Missense	distal	6	no	9.445	9.471	EPSD	COSMIC;CCLE	5.915	Up-regulation
CMGC_MAPK_p38_MAPK14_ST	P23769	GATA2	Q16539	MAPK14	S119	T117I	117	Missense	proximal	-2	no	9.445	9.347	EPSD	COSMIC	5.915	Down-regulation
CMGC_MAPK_p38_MAPK14_ST	P23769	GATA2	Q16539	MAPK14	S119	K123N	123	Missense	distal	4	no	9.445	8.895	EPSD	COSMIC;CCLE	5.915	Down-regulation
CMGC_MAPK_p38_MAPK14_ST	P23769	GATA2	Q16539	MAPK14	T176	L170F	170	Missense	distal	-6	no	6.856	6.312	EPSD	COSMIC	5.915	Down-regulation
CMGC_MAPK_p38_MAPK14_ST	P23769	GATA2	Q16539	MAPK14	T176	P177Q	177	Missense	proximal	1	no	6.856	-0.352	EPSD	COSMIC	5.915	Loss
CMGC_MAPK_p38_MAPK14_ST	P23769	GATA2	Q16539	MAPK14	S182	T188M	188	Missense	distal	6	no	10.864	10.876	EPSD	COSMIC	5.915	Up-regulation
CMGC_MAPK_p38_MAPK14_ST	P23769	GATA2	Q16539	MAPK14	S182	D184N	184	Missense	proximal	2	no	10.864	11.094	EPSD	COSMIC	5.915	Up-regulation
CMGC_MAPK_p38_MAPK14_ST	P23769	GATA2	Q16539	MAPK14	S182	P177Q	177	Missense	distal	-5	no	10.864	10.593	EPSD	COSMIC	5.915	Down-regulation
CMGC_MAPK_p38_MAPK14_ST	P23769	GATA2	Q16539	MAPK14	T188	T188M	188	Missense	central	0	yes	6.852	0.000	EPSD	COSMIC	5.915	Loss
CMGC_MAPK_p38_MAPK14_ST	P23769	GATA2	Q16539	MAPK14	T188	D184N	184	Missense	distal	-4	no	6.852	6.432	EPSD	COSMIC	5.915	Down-regulation
CMGC_MAPK_p38_MAPK14_ST	P23769	GATA2	Q16539	MAPK14	T188	A194V	194	Missense	distal	6	no	6.852	6.557	EPSD	COSMIC	5.915	Down-regulation
CMGC_MAPK_p38_MAPK14_ST	P23769	GATA2	Q16539	MAPK14	T188	S195P	195	Missense	distal	7	no	6.852	6.630	EPSD	COSMIC	5.915	Down-regulation
CMGC_MAPK_p38_MAPK14_ST	P23769	GATA2	Q16539	MAPK14	S192	T188M	188	Missense	distal	-4	no	14.920	14.714	PhosphoSitePlus	COSMIC	5.915	Down-regulation
CMGC_MAPK_p38_MAPK14_ST	P23769	GATA2	Q16539	MAPK14	S192	A194V	194	Missense	proximal	2	no	14.920	14.756	PhosphoSitePlus	COSMIC	5.915	Down-regulation
CMGC_MAPK_p38_MAPK14_ST	P23769	GATA2	Q16539	MAPK14	S192	A198V	198	Missense	distal	6	no	14.920	14.624	PhosphoSitePlus	COSMIC;GDSC;CCLE	5.915	Down-regulation
CMGC_MAPK_p38_MAPK14_ST	P23769	GATA2	Q16539	MAPK14	S192	S195P	195	Missense	distal	3	no	14.920	14.960	PhosphoSitePlus	COSMIC	5.915	Up-regulation
CMGC_MAPK_p38_MAPK14_ST	P23769	GATA2	Q16539	MAPK14	T303	P304L	304	Missense	proximal	1	no	9.980	1.929	EPSD	COSMIC	5.915	Loss
CMGC_MAPK_p38_MAPK14_ST	P23769	GATA2	Q16539	MAPK14	T303	R307W	307	Missense	distal	4	no	9.980	8.705	EPSD	COSMIC;CCLE	5.915	Down-regulation
CMGC_MAPK_p38_MAPK14_ST	P23769	GATA2	Q16539	MAPK14	T303	P304H	304	Missense	proximal	1	no	9.980	-3.674	EPSD	COSMIC	5.915	Loss
CMGC_MAPK_p38_MAPK14_ST	P23769	GATA2	Q16539	MAPK14	T303	P304T	304	Missense	proximal	1	no	9.980	2.526	EPSD	COSMIC	5.915	Loss
CMGC_MAPK_p38_MAPK14_ST	P23769	GATA2	Q16539	MAPK14	T303	R307L	307	Missense	distal	4	no	9.980	9.618	EPSD	COSMIC	5.915	Down-regulation
CMGC_MAPK_p38_MAPK14_ST	P23769	GATA2	Q16539	MAPK14	T303	N297K	297	Missense	distal	-6	no	9.980	9.818	EPSD	COSMIC	5.915	Down-regulation
CMGC_MAPK_p38_MAPK14_ST	P23769	GATA2	Q16539	MAPK14	T303	A302S	302	Missense	proximal	-1	no	9.980	9.920	EPSD	COSMIC	5.915	Down-regulation
CMGC_MAPK_p38_MAPK14_ST	P23769	GATA2	Q16539	MAPK14	T303	T303I	303	Missense	central	0	yes	9.980	0.000	EPSD	COSMIC	5.915	Loss
CMGC_MAPK_p38_MAPK14_ST	P23769	GATA2	Q16539	MAPK14	T303	N297S	297	Missense	distal	-6	no	9.980	10.403	EPSD	COSMIC	5.915	Up-regulation
CMGC_MAPK_p38_MAPK14_ST	P23769	GATA2	Q16539	MAPK14	T303	G299E	299	Missense	distal	-4	no	9.980	9.683	EPSD	COSMIC	5.915	Down-regulation
CMGC_MAPK_p38_MAPK14_ST	P23769	GATA2	Q16539	MAPK14	T303	D309V	309	Missense	distal	6	no	9.980	9.760	EPSD	COSMIC	5.915	Down-regulation
CMGC_MAPK_p38_MAPK14_ST	P23769	GATA2	Q16539	MAPK14	S340	K334T	334	Missense	distal	-6	no	5.903	6.216	EPSD	COSMIC	5.915	Gain
CMGC_MAPK_p38_MAPK14_ST	P23769	GATA2	Q16539	MAPK14	S340	T347A	347	Missense	distal	7	no	5.903	6.247	EPSD	COSMIC	5.915	Gain
CMGC_MAPK_p38_MAPK14_ST	P02511	CRYAB	Q16539	MAPK14	S19	R12H	12	Missense	distal	-7	no	10.811	10.517	EPSD	COSMIC;GDSC;CCLE	5.915	Down-regulation
CMGC_MAPK_p38_MAPK14_ST	P02511	CRYAB	Q16539	MAPK14	S19	F24L	24	Missense	distal	5	no	10.811	11.305	EPSD	COSMIC	5.915	Up-regulation
CMGC_MAPK_p38_MAPK14_ST	P02511	CRYAB	Q16539	MAPK14	S45	S45C	45	Missense	central	0	yes	10.021	0.000	EPSD	COSMIC	5.915	Loss
CMGC_MAPK_p38_MAPK14_ST	P02511	CRYAB	Q16539	MAPK14	S45	R50Q	50	Missense	distal	5	no	10.021	9.672	EPSD	COSMIC	5.915	Down-regulation
CMGC_MAPK_p38_MAPK14_ST	P02511	CRYAB	Q16539	MAPK14	S45	P46L	46	Missense	proximal	1	no	10.021	1.970	EPSD	COSMIC	5.915	Loss
CMGC_MAPK_p38_MAPK14_ST	P02511	CRYAB	Q16539	MAPK14	S59	R56Q	56	Missense	distal	-3	no	9.297	7.518	PhosphoSitePlus	COSMIC	5.915	Down-regulation
CMGC_MAPK_p38_MAPK14_ST	P02511	CRYAB	Q16539	MAPK14	S59	L65R	65	Missense	distal	6	no	9.297	9.424	PhosphoSitePlus	COSMIC	5.915	Up-regulation
CMGC_MAPK_p38_MAPK14_ST	P02511	CRYAB	Q16539	MAPK14	S85	E88G	88	Missense	distal	3	no	9.324	9.370	EPSD	COSMIC	5.915	Up-regulation
CMGC_MAPK_p38_MAPK14_ST	P02511	CRYAB	Q16539	MAPK14	S85	L89P	89	Missense	distal	4	no	9.324	9.964	EPSD	COSMIC	5.915	Up-regulation
CMGC_MAPK_p38_MAPK14_ST	P02511	CRYAB	Q16539	MAPK14	T132	S135L	135	Missense	distal	3	no	6.224	6.298	EPSD	COSMIC	5.915	Up-regulation
CMGC_MAPK_p38_MAPK14_ST	Q15910	EZH2	Q16539	MAPK14	S75	S75L	75	Missense	central	0	yes	7.697	0.000	EPSD	COSMIC	5.915	Loss
CMGC_MAPK_p38_MAPK14_ST	Q15910	EZH2	Q16539	MAPK14	S75	R78C	78	Missense	distal	3	no	7.697	7.753	EPSD	COSMIC	5.915	Up-regulation
CMGC_MAPK_p38_MAPK14_ST	Q15910	EZH2	Q16539	MAPK14	T261	I264T	264	Missense	distal	3	no	9.676	9.593	EPSD	COSMIC	5.915	Down-regulation
CMGC_MAPK_p38_MAPK14_ST	Q15910	EZH2	Q16539	MAPK14	T261	P262H	262	Missense	proximal	1	no	9.676	-3.978	EPSD	COSMIC	5.915	Loss
CMGC_MAPK_p38_MAPK14_ST	Q15910	EZH2	Q16539	MAPK14	T261	G254A	254	Missense	distal	-7	no	9.676	9.856	EPSD	COSMIC	5.915	Up-regulation
CMGC_MAPK_p38_MAPK14_ST	Q15910	EZH2	Q16539	MAPK14	T261	T261A	261	Missense	central	0	yes	9.676	0.000	EPSD	COSMIC	5.915	Loss
CMGC_MAPK_p38_MAPK14_ST	Q15910	EZH2	Q16539	MAPK14	T261	A255T	255	Missense	distal	-6	no	9.676	9.946	EPSD	COSMIC	5.915	Up-regulation
CMGC_MAPK_p38_MAPK14_ST	Q15910	EZH2	Q16539	MAPK14	T261	P262L	262	Missense	proximal	1	no	9.676	1.625	EPSD	COSMIC	5.915	Loss
CMGC_MAPK_p38_MAPK14_ST	Q15910	EZH2	Q16539	MAPK14	T261	P262T	262	Missense	proximal	1	no	9.676	2.222	EPSD	COSMIC	5.915	Loss
CMGC_MAPK_p38_MAPK14_ST	Q15910	EZH2	Q16539	MAPK14	T261	I264R	264	Missense	distal	3	no	9.676	9.607	EPSD	COSMIC	5.915	Down-regulation
CMGC_MAPK_p38_MAPK14_ST	Q15910	EZH2	Q16539	MAPK14	T261	G266E	266	Missense	distal	5	no	9.676	9.893	EPSD	COSMIC	5.915	Up-regulation
CMGC_MAPK_p38_MAPK14_ST	Q15910	EZH2	Q16539	MAPK14	T261	G266R	266	Missense	distal	5	no	9.676	9.621	EPSD	COSMIC	5.915	Down-regulation
CMGC_MAPK_p38_MAPK14_ST	Q15910	EZH2	Q16539	MAPK14	T261	T261N	261	Missense	central	0	yes	9.676	0.000	EPSD	COSMIC	5.915	Loss
CMGC_MAPK_p38_MAPK14_ST	Q15910	EZH2	Q16539	MAPK14	S277	H282Y	282	Missense	distal	5	no	5.214	5.940	EPSD	COSMIC	5.915	Gain
CMGC_MAPK_p38_MAPK14_ST	Q15910	EZH2	Q16539	MAPK14	T339	E333Q	333	Missense	distal	-6	no	6.862	6.256	EPSD	COSMIC	5.915	Down-regulation
CMGC_MAPK_p38_MAPK14_ST	Q15910	EZH2	Q16539	MAPK14	T339	R342W	342	Missense	distal	3	no	6.862	6.946	EPSD	COSMIC	5.915	Up-regulation
CMGC_MAPK_p38_MAPK14_ST	Q15910	EZH2	Q16539	MAPK14	T339	R342Q	342	Missense	distal	3	no	6.862	6.902	EPSD	COSMIC;CCLE	5.915	Up-regulation
CMGC_MAPK_p38_MAPK14_ST	Q15910	EZH2	Q16539	MAPK14	T339	R342L	342	Missense	distal	3	no	6.862	6.908	EPSD	COSMIC	5.915	Up-regulation
CMGC_MAPK_p38_MAPK14_ST	Q15910	EZH2	Q16539	MAPK14	T339	A340T	340	Missense	proximal	1	no	6.862	5.727	EPSD	COSMIC;CCLE	5.915	Loss
CMGC_MAPK_p38_MAPK14_ST	Q15910	EZH2	Q16539	MAPK14	T339	E341K	341	Missense	proximal	2	no	6.862	6.548	EPSD	COSMIC	5.915	Down-regulation
CMGC_MAPK_p38_MAPK14_ST	Q15910	EZH2	Q16539	MAPK14	T339	L338F	338	Missense	proximal	-1	no	6.862	6.826	EPSD	COSMIC	5.915	Down-regulation
CMGC_MAPK_p38_MAPK14_ST	Q15910	EZH2	Q16539	MAPK14	T345	R342W	342	Missense	distal	-3	no	12.244	9.887	EPSD	COSMIC	5.915	Down-regulation
CMGC_MAPK_p38_MAPK14_ST	Q15910	EZH2	Q16539	MAPK14	T345	R349C	349	Missense	distal	4	no	12.244	11.810	EPSD	COSMIC	5.915	Down-regulation
CMGC_MAPK_p38_MAPK14_ST	Q15910	EZH2	Q16539	MAPK14	T345	R342Q	342	Missense	distal	-3	no	12.244	10.465	EPSD	COSMIC;CCLE	5.915	Down-regulation
CMGC_MAPK_p38_MAPK14_ST	Q15910	EZH2	Q16539	MAPK14	T345	R342L	342	Missense	distal	-3	no	12.244	10.000	EPSD	COSMIC	5.915	Down-regulation
CMGC_MAPK_p38_MAPK14_ST	Q15910	EZH2	Q16539	MAPK14	T345	A340T	340	Missense	distal	-5	no	12.244	12.573	EPSD	COSMIC;CCLE	5.915	Up-regulation
CMGC_MAPK_p38_MAPK14_ST	Q15910	EZH2	Q16539	MAPK14	T345	E341K	341	Missense	distal	-4	no	12.244	12.469	EPSD	COSMIC	5.915	Up-regulation
CMGC_MAPK_p38_MAPK14_ST	Q15910	EZH2	Q16539	MAPK14	T345	L338F	338	Missense	distal	-7	no	12.244	11.778	EPSD	COSMIC	5.915	Down-regulation
CMGC_MAPK_p38_MAPK14_ST	Q15910	EZH2	Q16539	MAPK14	T367	S363N	363	Missense	distal	-4	no	12.855	12.928	PhosphoSitePlus	COSMIC	5.915	Up-regulation
CMGC_MAPK_p38_MAPK14_ST	Q15910	EZH2	Q16539	MAPK14	T367	P368S	368	Missense	proximal	1	no	12.855	5.572	PhosphoSitePlus	COSMIC	5.915	Loss
CMGC_MAPK_p38_MAPK14_ST	Q15910	EZH2	Q16539	MAPK14	T367	E374Q	374	Missense	distal	7	no	12.855	12.479	PhosphoSitePlus	COSMIC	5.915	Down-regulation
CMGC_MAPK_p38_MAPK14_ST	Q15910	EZH2	Q16539	MAPK14	T367	L373V	373	Missense	distal	6	no	12.855	12.742	PhosphoSitePlus	COSMIC	5.915	Down-regulation
CMGC_MAPK_p38_MAPK14_ST	Q15910	EZH2	Q16539	MAPK14	T367	S363C	363	Missense	distal	-4	no	12.855	13.317	PhosphoSitePlus	COSMIC	5.915	Up-regulation
CMGC_MAPK_p38_MAPK14_ST	Q15910	EZH2	Q16539	MAPK14	T367	N361T	361	Missense	distal	-6	no	12.855	13.006	PhosphoSitePlus	COSMIC	5.915	Up-regulation
CMGC_MAPK_p38_MAPK14_ST	Q15910	EZH2	Q16539	MAPK14	T367	S366L	366	Missense	proximal	-1	no	12.855	13.133	PhosphoSitePlus	COSMIC	5.915	Up-regulation
CMGC_MAPK_p38_MAPK14_ST	Q15910	EZH2	Q16539	MAPK14	S405	S405L	405	Missense	central	0	yes	6.166	0.000	EPSD	COSMIC	5.915	Loss
CMGC_MAPK_p38_MAPK14_ST	Q15910	EZH2	Q16539	MAPK14	S405	E409K	409	Missense	distal	4	no	6.166	5.700	EPSD	COSMIC	5.915	Loss
CMGC_MAPK_p38_MAPK14_ST	Q15910	EZH2	Q16539	MAPK14	S405	S408F	408	Missense	distal	3	no	6.166	6.274	EPSD	COSMIC	5.915	Up-regulation
CMGC_MAPK_p38_MAPK14_ST	Q15910	EZH2	Q16539	MAPK14	S405	S412F	412	Missense	distal	7	no	6.166	5.296	EPSD	COSMIC	5.915	Loss
CMGC_MAPK_p38_MAPK14_ST	Q15910	EZH2	Q16539	MAPK14	T416	P422L	422	Missense	distal	6	no	10.218	10.079	EPSD	COSMIC	5.915	Down-regulation
CMGC_MAPK_p38_MAPK14_ST	Q15910	EZH2	Q16539	MAPK14	T416	P422Q	422	Missense	distal	6	no	10.218	10.217	EPSD	COSMIC	5.915	Down-regulation
CMGC_MAPK_p38_MAPK14_ST	Q15910	EZH2	Q16539	MAPK14	T416	R413W	413	Missense	distal	-3	no	10.218	7.861	EPSD	COSMIC	5.915	Down-regulation
CMGC_MAPK_p38_MAPK14_ST	Q15910	EZH2	Q16539	MAPK14	T416	P417L	417	Missense	proximal	1	no	10.218	2.167	EPSD	COSMIC	5.915	Loss
CMGC_MAPK_p38_MAPK14_ST	Q15910	EZH2	Q16539	MAPK14	T416	E409K	409	Missense	distal	-7	no	10.218	10.164	EPSD	COSMIC	5.915	Down-regulation
CMGC_MAPK_p38_MAPK14_ST	Q15910	EZH2	Q16539	MAPK14	T416	S412F	412	Missense	distal	-4	no	10.218	10.922	EPSD	COSMIC	5.915	Up-regulation
CMGC_MAPK_p38_MAPK14_ST	Q15910	EZH2	Q16539	MAPK14	T416	N423T	423	Missense	distal	7	no	10.218	10.195	EPSD	COSMIC	5.915	Down-regulation
CMGC_MAPK_p38_MAPK14_ST	Q15910	EZH2	Q16539	MAPK14	T416	Q415E	415	Missense	proximal	-1	no	10.218	10.149	EPSD	COSMIC	5.915	Down-regulation
CMGC_MAPK_p38_MAPK14_ST	Q15910	EZH2	Q16539	MAPK14	T416	P417Q	417	Missense	proximal	1	no	10.218	3.009	EPSD	COSMIC	5.915	Loss
CMGC_MAPK_p38_MAPK14_ST	Q15910	EZH2	Q16539	MAPK14	T416	R413Q	413	Missense	distal	-3	no	10.218	8.438	EPSD	COSMIC;CCLE	5.915	Down-regulation
CMGC_MAPK_p38_MAPK14_ST	Q15910	EZH2	Q16539	MAPK14	T487	A482T	482	Missense	distal	-5	no	10.172	10.501	EPSD	COSMIC	5.915	Up-regulation
CMGC_MAPK_p38_MAPK14_ST	Q15910	EZH2	Q16539	MAPK14	T487	P488S	488	Missense	proximal	1	no	10.172	2.888	EPSD	COSMIC	5.915	Loss
CMGC_MAPK_p38_MAPK14_ST	Q15910	EZH2	Q16539	MAPK14	T487	R494S	494	Missense	distal	7	no	10.172	10.138	EPSD	COSMIC	5.915	Down-regulation
CMGC_MAPK_p38_MAPK14_ST	Q15910	EZH2	Q16539	MAPK14	T487	R494K	494	Missense	distal	7	no	10.172	9.648	EPSD	COSMIC	5.915	Down-regulation
CMGC_MAPK_p38_MAPK14_ST	Q15910	EZH2	Q16539	MAPK14	T487	P481S	481	Missense	distal	-6	no	10.172	10.779	EPSD	COSMIC	5.915	Up-regulation
CMGC_MAPK_p38_MAPK14_ST	Q15910	EZH2	Q16539	MAPK14	T487	P488A	488	Missense	proximal	1	no	10.172	3.854	EPSD	COSMIC	5.915	Loss
CMGC_MAPK_p38_MAPK14_ST	Q15910	EZH2	Q16539	MAPK14	T487	K491R	491	Missense	distal	4	no	10.172	9.421	EPSD	COSMIC	5.915	Down-regulation
CMGC_MAPK_p38_MAPK14_ST	P36956	SREBF1	Q16539	MAPK14	S402	S396F	396	Missense	distal	-6	no	7.517	5.753	PhosphoSitePlus	COSMIC	5.915	Loss
CMGC_MAPK_p38_MAPK14_ST	P36956	SREBF1	Q16539	MAPK14	S402	C404R	404	Missense	proximal	2	no	7.517	7.785	PhosphoSitePlus	COSMIC;CCLE	5.915	Up-regulation
CMGC_MAPK_p38_MAPK14_ST	P36956	SREBF1	Q16539	MAPK14	S402	K395N	395	Missense	distal	-7	no	7.517	7.209	PhosphoSitePlus	COSMIC	5.915	Down-regulation
CMGC_MAPK_p38_MAPK14_ST	Q01844	EWSR1	Q16539	MAPK14	T79	T81S	81	Missense	proximal	2	no	12.266	12.502	PhosphoSitePlus	COSMIC	5.915	Up-regulation
CMGC_MAPK_p38_MAPK14_ST	Q01844	EWSR1	Q16539	MAPK14	T79	T75A	75	Missense	distal	-4	no	12.266	12.029	PhosphoSitePlus	COSMIC	5.915	Down-regulation
CMGC_MAPK_p38_MAPK14_ST	Q01844	EWSR1	Q16539	MAPK14	T79	P83H	83	Missense	distal	4	no	12.266	11.596	PhosphoSitePlus	COSMIC	5.915	Down-regulation
CMGC_MAPK_p38_MAPK14_ST	Q01844	EWSR1	Q16539	MAPK14	T79	T78I	78	Missense	proximal	-1	no	12.266	12.128	PhosphoSitePlus	COSMIC	5.915	Down-regulation
CMGC_MAPK_p38_MAPK14_ST	Q01844	EWSR1	Q16539	MAPK14	T81	T75A	75	Missense	distal	-6	no	7.685	7.415	EPSD	COSMIC	5.915	Down-regulation
CMGC_MAPK_p38_MAPK14_ST	Q01844	EWSR1	Q16539	MAPK14	T81	S87I	87	Missense	distal	6	no	7.685	7.474	EPSD	COSMIC	5.915	Down-regulation
CMGC_MAPK_p38_MAPK14_ST	Q01844	EWSR1	Q16539	MAPK14	T81	P83H	83	Missense	proximal	2	no	7.685	7.533	EPSD	COSMIC	5.915	Down-regulation
CMGC_MAPK_p38_MAPK14_ST	Q01844	EWSR1	Q16539	MAPK14	T81	T78I	78	Missense	distal	-3	no	7.685	5.930	EPSD	COSMIC	5.915	Down-regulation
CMGC_MAPK_p38_MAPK14_ST	P56817	BACE1	Q16539	MAPK14	S59	F60L	60	Missense	proximal	1	no	6.121	4.074	EPSD	COSMIC	5.915	Loss
CMGC_MAPK_p38_MAPK14_ST	P56817	BACE1	Q16539	MAPK14	S59	R57C	57	Missense	proximal	-2	no	6.121	5.185	EPSD	COSMIC	5.915	Loss
CMGC_MAPK_p38_MAPK14_ST	P56817	BACE1	Q16539	MAPK14	T252	G247C	247	Missense	distal	-5	no	10.102	10.422	EPSD	COSMIC;GDSC;CCLE	5.915	Up-regulation
CMGC_MAPK_p38_MAPK14_ST	P56817	BACE1	Q16539	MAPK14	T252	P253S	253	Missense	proximal	1	no	10.102	2.818	EPSD	COSMIC	5.915	Loss
CMGC_MAPK_p38_MAPK14_ST	P56817	BACE1	Q16539	MAPK14	T252	E257Q	257	Missense	distal	5	no	10.102	9.481	EPSD	COSMIC	5.915	Down-regulation
CMGC_MAPK_p38_MAPK14_ST	P56817	BACE1	Q16539	MAPK14	T252	R255W	255	Missense	distal	3	no	10.102	10.186	EPSD	COSMIC	5.915	Up-regulation
CMGC_MAPK_p38_MAPK14_ST	P56817	BACE1	Q16539	MAPK14	T252	R256G	256	Missense	distal	4	no	10.102	10.587	EPSD	COSMIC	5.915	Up-regulation
CMGC_MAPK_p38_MAPK14_ST	P56817	BACE1	Q16539	MAPK14	T252	R256Q	256	Missense	distal	4	no	10.102	9.898	EPSD	COSMIC	5.915	Down-regulation
CMGC_MAPK_p38_MAPK14_ST	P56817	BACE1	Q16539	MAPK14	T252	G247D	247	Missense	distal	-5	no	10.102	10.344	EPSD	COSMIC	5.915	Up-regulation
CMGC_MAPK_p38_MAPK14_ST	P56817	BACE1	Q16539	MAPK14	T252	T246M	246	Missense	distal	-6	no	10.102	9.514	EPSD	COSMIC	5.915	Down-regulation
CMGC_MAPK_p38_MAPK14_ST	O15198	SMAD9	Q16539	MAPK14	S8	S9F	9	Missense	proximal	1	no	5.523	6.803	EPSD	COSMIC;GDSC;CCLE	5.915	Gain
CMGC_MAPK_p38_MAPK14_ST	O15198	SMAD9	Q16539	MAPK14	S15	P16L	16	Missense	proximal	1	no	12.194	4.143	EPSD	COSMIC	5.915	Loss
CMGC_MAPK_p38_MAPK14_ST	O15198	SMAD9	Q16539	MAPK14	S15	S9F	9	Missense	distal	-6	no	12.194	10.430	EPSD	COSMIC;GDSC;CCLE	5.915	Down-regulation
CMGC_MAPK_p38_MAPK14_ST	O15198	SMAD9	Q16539	MAPK14	S15	T14S	14	Missense	proximal	-1	no	12.194	12.078	EPSD	COSMIC	5.915	Down-regulation
CMGC_MAPK_p38_MAPK14_ST	O15198	SMAD9	Q16539	MAPK14	T136	H130L	130	Missense	distal	-6	no	10.665	10.514	PhosphoSitePlus	COSMIC	5.915	Down-regulation
CMGC_MAPK_p38_MAPK14_ST	O15198	SMAD9	Q16539	MAPK14	S458	K451T	451	Missense	distal	-7	no	8.843	8.677	EPSD	COSMIC	5.915	Down-regulation
CMGC_MAPK_p38_MAPK14_ST	Q92945	KHSRP	Q16539	MAPK14	T100	N97S	97	Missense	distal	-3	no	8.246	9.393	EPSD	COSMIC	5.915	Up-regulation
CMGC_MAPK_p38_MAPK14_ST	Q92945	KHSRP	Q16539	MAPK14	T100	T94M	94	Missense	distal	-6	no	8.246	7.658	EPSD	COSMIC	5.915	Down-regulation
CMGC_MAPK_p38_MAPK14_ST	Q92945	KHSRP	Q16539	MAPK14	S181	D183V	183	Missense	proximal	2	no	9.083	9.141	EPSD	COSMIC	5.915	Up-regulation
CMGC_MAPK_p38_MAPK14_ST	Q92945	KHSRP	Q16539	MAPK14	S181	G185A	185	Missense	distal	4	no	9.083	9.009	EPSD	COSMIC	5.915	Down-regulation
CMGC_MAPK_p38_MAPK14_ST	Q92945	KHSRP	Q16539	MAPK14	S480	I476N	476	Missense	distal	-4	no	9.381	9.286	EPSD	COSMIC;GDSC;CCLE	5.915	Down-regulation
CMGC_MAPK_p38_MAPK14_ST	Q92945	KHSRP	Q16539	MAPK14	T692	G697S	697	Missense	distal	5	no	12.764	13.019	PhosphoSitePlus	COSMIC	5.915	Up-regulation
CMGC_MAPK_p38_MAPK14_ST	O43257	ZNHIT1	Q16539	MAPK14	T103	P109L	109	Missense	distal	6	no	8.174	8.035	PhosphoSitePlus	COSMIC	5.915	Down-regulation
CMGC_MAPK_p38_MAPK14_ST	O43257	ZNHIT1	Q16539	MAPK14	T103	G98D	98	Missense	distal	-5	no	8.174	8.416	PhosphoSitePlus	COSMIC	5.915	Up-regulation
CMGC_MAPK_p38_MAPK14_ST	P05198	EIF2S1	Q16539	MAPK14	S52	L48V	48	Missense	distal	-4	no	7.729	7.452	PhosphoSitePlus	COSMIC	5.915	Down-regulation
CMGC_MAPK_p38_MAPK14_ST	P05198	EIF2S1	Q16539	MAPK14	S52	R55H	55	Missense	distal	3	no	7.729	7.800	PhosphoSitePlus	COSMIC	5.915	Up-regulation
CMGC_MAPK_p38_MAPK14_ST	P05198	EIF2S1	Q16539	MAPK14	S52	R55C	55	Missense	distal	3	no	7.729	7.785	PhosphoSitePlus	COSMIC	5.915	Up-regulation
CMGC_MAPK_p38_MAPK14_ST	Q13309	SKP2	Q16539	MAPK14	S64	L70R	70	Missense	distal	6	no	9.493	9.620	PhosphoSitePlus	COSMIC	5.915	Up-regulation
CMGC_MAPK_p38_MAPK14_ST	Q13309	SKP2	Q16539	MAPK14	S179	P173T	173	Missense	distal	-6	no	7.705	8.039	EPSD	COSMIC;CCLE	5.915	Up-regulation
CMGC_MAPK_p38_MAPK14_ST	Q13309	SKP2	Q16539	MAPK14	S179	P173Q	173	Missense	distal	-6	no	7.705	7.536	EPSD	COSMIC;CCLE	5.915	Down-regulation
CMGC_MAPK_p38_MAPK14_ST	Q13309	SKP2	Q16539	MAPK14	S179	S179L	179	Missense	central	0	yes	7.705	0.000	EPSD	COSMIC	5.915	Loss
CMGC_MAPK_p38_MAPK14_ST	Q13309	SKP2	Q16539	MAPK14	S303	D301G	301	Missense	proximal	-2	no	5.485	6.235	EPSD	COSMIC;GDSC	5.915	Gain
CMGC_MAPK_p38_MAPK14_ST	Q9H3M7	TXNIP	Q16539	MAPK14	T306	S307Y	307	Missense	proximal	1	no	6.507	6.514	EPSD	COSMIC	5.915	Up-regulation
CMGC_MAPK_p38_MAPK14_ST	Q9H3M7	TXNIP	Q16539	MAPK14	S307	S307Y	307	Missense	central	0	yes	8.311	0.000	EPSD	COSMIC	5.915	Loss
CMGC_MAPK_p38_MAPK14_ST	Q9H3M7	TXNIP	Q16539	MAPK14	S311	E316K	316	Missense	distal	5	no	7.110	6.543	EPSD	COSMIC	5.915	Down-regulation
CMGC_MAPK_p38_MAPK14_ST	Q9H3M7	TXNIP	Q16539	MAPK14	S311	S307Y	307	Missense	distal	-4	no	7.110	7.106	EPSD	COSMIC	5.915	Down-regulation
CMGC_MAPK_p38_MAPK14_ST	Q9H3M7	TXNIP	Q16539	MAPK14	S346	R343Q	343	Missense	distal	-3	no	11.185	9.406	EPSD	COSMIC;GDSC	5.915	Down-regulation
CMGC_MAPK_p38_MAPK14_ST	Q9H3M7	TXNIP	Q16539	MAPK14	S346	D341G	341	Missense	distal	-5	no	11.185	10.943	EPSD	COSMIC	5.915	Down-regulation
CMGC_MAPK_p38_MAPK14_ST	Q9H3M7	TXNIP	Q16539	MAPK14	T349	R343Q	343	Missense	distal	-6	no	10.803	10.133	EPSD	COSMIC;GDSC	5.915	Down-regulation
CMGC_MAPK_p38_MAPK14_ST	Q9H3M7	TXNIP	Q16539	MAPK14	S361	I363N	363	Missense	proximal	2	no	10.642	10.865	PhosphoSitePlus	COSMIC;GDSC;CCLE	5.915	Up-regulation
CMGC_MAPK_p38_MAPK14_ST	Q9H3M7	TXNIP	Q16539	MAPK14	S361	D360H	360	Missense	proximal	-1	no	10.642	10.433	PhosphoSitePlus	COSMIC	5.915	Down-regulation
CMGC_MAPK_p38_MAPK14_ST	Q9H3M7	TXNIP	Q16539	MAPK14	S361	G357D	357	Missense	distal	-4	no	10.642	11.138	PhosphoSitePlus	COSMIC	5.915	Up-regulation
CMGC_MAPK_p38_MAPK14_ST	P18850	ATF6	Q16539	MAPK14	S13	S16I	16	Missense	distal	3	no	10.641	10.737	EPSD	COSMIC	5.915	Up-regulation
CMGC_MAPK_p38_MAPK14_ST	P18850	ATF6	Q16539	MAPK14	S13	G6W	6	Missense	distal	-7	no	10.641	9.800	EPSD	COSMIC	5.915	Down-regulation
CMGC_MAPK_p38_MAPK14_ST	P18850	ATF6	Q16539	MAPK14	S13	G18E	18	Missense	distal	5	no	10.641	10.858	EPSD	COSMIC	5.915	Up-regulation
CMGC_MAPK_p38_MAPK14_ST	P18850	ATF6	Q16539	MAPK14	S13	P17L	17	Missense	distal	4	no	10.641	10.002	EPSD	COSMIC	5.915	Down-regulation
CMGC_MAPK_p38_MAPK14_ST	P18850	ATF6	Q16539	MAPK14	S16	S16I	16	Missense	central	0	yes	10.902	0.000	EPSD	COSMIC	5.915	Loss
CMGC_MAPK_p38_MAPK14_ST	P18850	ATF6	Q16539	MAPK14	S16	G18E	18	Missense	proximal	2	no	10.902	11.096	EPSD	COSMIC	5.915	Up-regulation
CMGC_MAPK_p38_MAPK14_ST	P18850	ATF6	Q16539	MAPK14	S16	P17L	17	Missense	proximal	1	no	10.902	2.851	EPSD	COSMIC	5.915	Loss
CMGC_MAPK_p38_MAPK14_ST	P18850	ATF6	Q16539	MAPK14	S104	R106W	106	Missense	proximal	2	no	10.523	10.025	EPSD	COSMIC	5.915	Down-regulation
CMGC_MAPK_p38_MAPK14_ST	P18850	ATF6	Q16539	MAPK14	T166	P167L	167	Missense	proximal	1	no	8.902	0.851	PhosphoSitePlus	COSMIC	5.915	Loss
CMGC_MAPK_p38_MAPK14_ST	P18850	ATF6	Q16539	MAPK14	S410	Q414E	414	Missense	distal	4	no	8.308	9.729	EPSD	COSMIC	5.915	Up-regulation
CMGC_MAPK_p38_MAPK14_ST	P18850	ATF6	Q16539	MAPK14	S410	R404K	404	Missense	distal	-6	no	8.308	7.829	EPSD	COSMIC	5.915	Down-regulation
CMGC_MAPK_p38_MAPK14_ST	P18850	ATF6	Q16539	MAPK14	S410	R403S	403	Missense	distal	-7	no	8.308	8.476	EPSD	COSMIC	5.915	Up-regulation
Other_NAK_BIKE_AAK1_ST	P49757	NUMB	Q2M2I8	AAK1	T243	S241N	241	Missense	proximal	-2	no	2.906	2.889	EPSD	COSMIC	2.491	Down-regulation
Other_NAK_BIKE_AAK1_ST	P49757	NUMB	Q2M2I8	AAK1	T243	P242L	242	Missense	proximal	-1	no	2.906	2.882	EPSD	COSMIC	2.491	Down-regulation
Other_NAK_BIKE_AAK1_ST	P49757	NUMB	Q2M2I8	AAK1	T246	S241N	241	Missense	distal	-5	no	2.702	2.698	EPSD	COSMIC	2.491	Down-regulation
Other_NAK_BIKE_AAK1_ST	P49757	NUMB	Q2M2I8	AAK1	T246	P242L	242	Missense	distal	-4	no	2.702	2.623	EPSD	COSMIC	2.491	Down-regulation
Other_NAK_BIKE_AAK1_ST	P49757	NUMB	Q2M2I8	AAK1	T251	E254K	254	Missense	distal	3	no	3.014	3.028	EPSD	COSMIC	2.491	Up-regulation
Other_NAK_BIKE_AAK1_ST	P49757	NUMB	Q2M2I8	AAK1	S284	P281S	281	Missense	distal	-3	no	3.653	3.797	EPSD	COSMIC	2.491	Up-regulation
Other_NAK_BIKE_AAK1_ST	P49757	NUMB	Q2M2I8	AAK1	S284	P281H	281	Missense	distal	-3	no	3.653	3.695	EPSD	COSMIC	2.491	Up-regulation
Other_NAK_BIKE_AAK1_ST	P49757	NUMB	Q2M2I8	AAK1	S284	M287L	287	Missense	distal	3	no	3.653	3.681	EPSD	COSMIC	2.491	Up-regulation
Other_NAK_BIKE_AAK1_ST	P49757	NUMB	Q2M2I8	AAK1	S284	R278P	278	Missense	distal	-6	no	3.653	2.897	EPSD	COSMIC	2.491	Down-regulation
Other_NAK_BIKE_AAK1_ST	P49757	NUMB	Q2M2I8	AAK1	T369	G368C	368	Missense	proximal	-1	no	2.703	2.731	EPSD	COSMIC	2.491	Up-regulation
Other_NAK_BIKE_AAK1_ST	P49757	NUMB	Q2M2I8	AAK1	T369	A372T	372	Missense	distal	3	no	2.703	2.714	EPSD	COSMIC	2.491	Up-regulation
Other_NAK_BIKE_AAK1_ST	P49757	NUMB	Q2M2I8	AAK1	T631	P633S	633	Missense	proximal	2	no	3.039	2.980	EPSD	COSMIC	2.491	Down-regulation
Other_NAK_BIKE_AAK1_ST	Q96CW1	AP2M1	Q2M2I8	AAK1	T134	Q135K	135	Missense	proximal	1	no	2.496	2.617	EPSD	COSMIC	2.491	Up-regulation
Other_NAK_BIKE_AAK1_ST	Q96CW1	AP2M1	Q2M2I8	AAK1	T156	S149F	149	Missense	distal	-7	no	9.991	9.782	PhosphoSitePlus	COSMIC	2.491	Down-regulation
Other_NAK_BIKE_AAK1_ST	Q96CW1	AP2M1	Q2M2I8	AAK1	T156	G160C	160	Missense	distal	4	no	9.991	9.563	PhosphoSitePlus	COSMIC	2.491	Down-regulation
Other_NAK_BIKE_AAK1_ST	Q96CW1	AP2M1	Q2M2I8	AAK1	T156	Q150E	150	Missense	distal	-6	no	9.991	10.050	PhosphoSitePlus	COSMIC	2.491	Up-regulation
Other_NAK_BIKE_AAK1_ST	Q96CW1	AP2M1	Q2M2I8	AAK1	T233	D231G	231	Missense	proximal	-2	no	3.105	3.100	EPSD	COSMIC	2.491	Down-regulation
Other_NAK_BIKE_AAK1_ST	Q96CW1	AP2M1	Q2M2I8	AAK1	T233	G237E	237	Missense	distal	4	no	3.105	2.309	EPSD	COSMIC	2.491	Loss
Other_NAK_BIKE_AAK1_ST	Q96CW1	AP2M1	Q2M2I8	AAK1	T233	G237R	237	Missense	distal	4	no	3.105	2.995	EPSD	COSMIC	2.491	Down-regulation
Other_NAK_BIKE_AAK1_ST	Q96CW1	AP2M1	Q2M2I8	AAK1	T247	D244N	244	Missense	distal	-3	no	2.562	2.586	EPSD	COSMIC	2.491	Up-regulation
Other_NAK_BIKE_AAK1_ST	Q96CW1	AP2M1	Q2M2I8	AAK1	T247	D244G	244	Missense	distal	-3	no	2.562	2.496	EPSD	COSMIC	2.491	Down-regulation
Other_NAK_BIKE_AAK1_ST	Q96CW1	AP2M1	Q2M2I8	AAK1	T247	Q250R	250	Missense	distal	3	no	2.562	2.528	EPSD	COSMIC	2.491	Down-regulation
Other_NAK_BIKE_AAK1_ST	Q96CW1	AP2M1	Q2M2I8	AAK1	T247	I241N	241	Missense	distal	-6	no	2.562	2.871	EPSD	COSMIC;CCLE	2.491	Up-regulation
Other_NAK_BIKE_AAK1_ST	Q96CW1	AP2M1	Q2M2I8	AAK1	T247	D245G	245	Missense	proximal	-2	no	2.562	2.558	EPSD	COSMIC	2.491	Down-regulation
Other_NAK_BIKE_AAK1_ST	Q96CW1	AP2M1	Q2M2I8	AAK1	T247	I241V	241	Missense	distal	-6	no	2.562	2.672	EPSD	COSMIC	2.491	Up-regulation
Other_NAK_BIKE_AAK1_ST	Q96CW1	AP2M1	Q2M2I8	AAK1	T247	I243N	243	Missense	distal	-4	no	2.562	2.681	EPSD	COSMIC;GDSC	2.491	Up-regulation
TK_Fer_FES_Y	P07332	FES	P07332	FES	Y261	Q256H	256	Missense	distal	-5	no	8.730	9.777	EPSD	COSMIC	7.476	Up-regulation
TK_Fer_FES_Y	P07332	FES	P07332	FES	Y713	R720H	720	Missense	distal	7	no	18.369	18.206	EPSD;PhosphoSitePlus	COSMIC	7.476	Down-regulation
TK_Fer_FES_Y	P07332	FES	P07332	FES	Y713	R720C	720	Missense	distal	7	no	18.369	18.381	EPSD;PhosphoSitePlus	COSMIC	7.476	Up-regulation
TK_Fer_FES_Y	P07332	FES	P07332	FES	Y713	A714T	714	Missense	proximal	1	no	18.369	18.134	EPSD;PhosphoSitePlus	COSMIC;GDSC	7.476	Down-regulation
TK_Fer_FES_Y	P07332	FES	P07332	FES	Y713	G717V	717	Missense	distal	4	no	18.369	18.707	EPSD;PhosphoSitePlus	COSMIC	7.476	Up-regulation
TK_Fer_FES_Y	P07332	FES	P07332	FES	Y713	D710N	710	Missense	distal	-3	no	18.369	16.282	EPSD;PhosphoSitePlus	COSMIC	7.476	Down-regulation
TK_Fer_FES_Y	P11274	BCR	P07332	FES	Y177	E181D	181	Missense	distal	4	no	15.215	14.696	EPSD	COSMIC	7.476	Down-regulation
TK_Fer_FES_Y	P11274	BCR	P07332	FES	Y231	P229S	229	Missense	proximal	-2	no	7.323	8.509	EPSD	COSMIC	7.476	Gain
TK_Fer_FES_Y	P11274	BCR	P07332	FES	Y246	G241S	241	Missense	distal	-5	no	20.307	19.962	PhosphoSitePlus	COSMIC	7.476	Down-regulation
TK_Fer_FES_Y	P11274	BCR	P07332	FES	Y276	I282M	282	Missense	distal	6	no	14.785	14.759	EPSD	COSMIC	7.476	Down-regulation
TK_Fer_FES_Y	P11274	BCR	P07332	FES	Y276	E275D	275	Missense	proximal	-1	no	14.785	14.808	EPSD	COSMIC	7.476	Up-regulation
TK_Fer_FES_Y	P11274	BCR	P07332	FES	Y276	P278S	278	Missense	proximal	2	no	14.785	14.782	EPSD	COSMIC	7.476	Down-regulation
TK_Fer_FES_Y	P11274	BCR	P07332	FES	Y276	P272L	272	Missense	distal	-4	no	14.785	14.820	EPSD	COSMIC	7.476	Up-regulation
TK_Fer_FES_Y	P11274	BCR	P07332	FES	Y279	I282M	282	Missense	distal	3	no	16.933	16.631	EPSD	COSMIC	7.476	Down-regulation
TK_Fer_FES_Y	P11274	BCR	P07332	FES	Y279	E275D	275	Missense	distal	-4	no	16.933	16.961	EPSD	COSMIC	7.476	Up-regulation
TK_Fer_FES_Y	P11274	BCR	P07332	FES	Y279	P278S	278	Missense	proximal	-1	no	16.933	16.925	EPSD	COSMIC	7.476	Down-regulation
TK_Fer_FES_Y	P11274	BCR	P07332	FES	Y279	P272L	272	Missense	distal	-7	no	16.933	16.792	EPSD	COSMIC	7.476	Down-regulation
TK_Fer_FES_Y	P11274	BCR	P07332	FES	Y279	V284L	284	Missense	distal	5	no	16.933	16.853	EPSD	COSMIC	7.476	Down-regulation
TK_Fer_FES_Y	P11274	BCR	P07332	FES	Y283	I282M	282	Missense	proximal	-1	no	15.668	15.658	EPSD	COSMIC	7.476	Down-regulation
TK_Fer_FES_Y	P11274	BCR	P07332	FES	Y283	E289G	289	Missense	distal	6	no	15.668	15.820	EPSD	COSMIC	7.476	Up-regulation
TK_Fer_FES_Y	P11274	BCR	P07332	FES	Y283	P278S	278	Missense	distal	-5	no	15.668	15.757	EPSD	COSMIC	7.476	Up-regulation
TK_Fer_FES_Y	P11274	BCR	P07332	FES	Y283	V284L	284	Missense	proximal	1	no	15.668	13.336	EPSD	COSMIC	7.476	Down-regulation
TK_Fer_FES_Y	P11274	BCR	P07332	FES	Y360	R364Q	364	Missense	distal	4	no	6.715	7.527	EPSD	COSMIC	7.476	Gain
Other_IKK_CHUK_ST	Q9Y6Q9	NCOA3	O15111	CHUK	S214	R218C	218	Missense	distal	4	no	199.228	192.541	EPSD	COSMIC	187.474	Down-regulation
Other_IKK_CHUK_ST	Q9Y6Q9	NCOA3	O15111	CHUK	S214	E209K	209	Missense	distal	-5	no	199.228	208.619	EPSD	COSMIC	187.474	Up-regulation
Other_IKK_CHUK_ST	Q9Y6Q9	NCOA3	O15111	CHUK	S214	R218H	218	Missense	distal	4	no	199.228	190.818	EPSD	COSMIC	187.474	Down-regulation
Other_IKK_CHUK_ST	Q9Y6Q9	NCOA3	O15111	CHUK	S214	M217I	217	Missense	distal	3	no	199.228	157.291	EPSD	COSMIC	187.474	Loss
Other_IKK_CHUK_ST	Q9Y6Q9	NCOA3	O15111	CHUK	S214	Y221H	221	Missense	distal	7	no	199.228	202.833	EPSD	COSMIC	187.474	Up-regulation
Other_IKK_CHUK_ST	Q9Y6Q9	NCOA3	O15111	CHUK	S214	A213T	213	Missense	proximal	-1	no	199.228	201.341	EPSD	COSMIC;GDSC	187.474	Up-regulation
Other_IKK_CHUK_ST	Q9Y6Q9	NCOA3	O15111	CHUK	S214	E209D	209	Missense	distal	-5	no	199.228	224.430	EPSD	COSMIC	187.474	Up-regulation
Other_IKK_CHUK_ST	Q9Y6Q9	NCOA3	O15111	CHUK	S288	M289L	289	Missense	proximal	1	no	220.740	225.939	EPSD	COSMIC	187.474	Up-regulation
Other_IKK_CHUK_ST	Q9Y6Q9	NCOA3	O15111	CHUK	S288	S288F	288	Missense	central	0	yes	220.740	0.000	EPSD	COSMIC	187.474	Loss
Other_IKK_CHUK_ST	Q9Y6Q9	NCOA3	O15111	CHUK	S288	R286K	286	Missense	proximal	-2	no	220.740	212.468	EPSD	COSMIC	187.474	Down-regulation
Other_IKK_CHUK_ST	Q9Y6Q9	NCOA3	O15111	CHUK	S288	T282P	282	Missense	distal	-6	no	220.740	227.884	EPSD	COSMIC	187.474	Up-regulation
Other_IKK_CHUK_ST	Q9Y6Q9	NCOA3	O15111	CHUK	S306	R303I	303	Missense	distal	-3	no	230.226	218.409	EPSD	COSMIC	187.474	Down-regulation
Other_IKK_CHUK_ST	Q9Y6Q9	NCOA3	O15111	CHUK	S567	D566Y	566	Missense	proximal	-1	no	195.398	192.487	EPSD	COSMIC	187.474	Down-regulation
Other_IKK_CHUK_ST	Q9Y6Q9	NCOA3	O15111	CHUK	S567	N564S	564	Missense	distal	-3	no	195.398	192.089	EPSD	COSMIC	187.474	Down-regulation
Other_IKK_CHUK_ST	Q9Y6Q9	NCOA3	O15111	CHUK	S569	D576N	576	Missense	distal	7	no	196.837	193.151	EPSD	COSMIC	187.474	Down-regulation
Other_IKK_CHUK_ST	Q9Y6Q9	NCOA3	O15111	CHUK	S569	D566Y	566	Missense	distal	-3	no	196.837	197.763	EPSD	COSMIC	187.474	Up-regulation
Other_IKK_CHUK_ST	Q9Y6Q9	NCOA3	O15111	CHUK	S569	N564S	564	Missense	distal	-5	no	196.837	206.676	EPSD	COSMIC	187.474	Up-regulation
Other_IKK_CHUK_ST	Q9Y6Q9	NCOA3	O15111	CHUK	S587	R590T	590	Missense	distal	3	no	164.497	199.163	EPSD	COSMIC	187.474	Gain
Other_IKK_CHUK_ST	Q9Y6Q9	NCOA3	O15111	CHUK	S587	R590K	590	Missense	distal	3	no	164.497	197.634	EPSD	COSMIC	187.474	Gain
Other_IKK_CHUK_ST	Q9Y6Q9	NCOA3	O15111	CHUK	S598	S594G	594	Missense	distal	-4	no	189.498	178.933	EPSD	COSMIC	187.474	Loss
Other_IKK_CHUK_ST	Q9Y6Q9	NCOA3	O15111	CHUK	S598	S601N	601	Missense	distal	3	no	189.498	192.195	EPSD	COSMIC	187.474	Up-regulation
Other_IKK_CHUK_ST	Q9Y6Q9	NCOA3	O15111	CHUK	S598	S598R	598	Missense	central	0	yes	189.498	0.000	EPSD	COSMIC	187.474	Loss
Other_IKK_CHUK_ST	Q9Y6Q9	NCOA3	O15111	CHUK	S598	L593H	593	Missense	distal	-5	no	189.498	190.601	EPSD	COSMIC	187.474	Up-regulation
Other_IKK_CHUK_ST	Q9Y6Q9	NCOA3	O15111	CHUK	S598	G605W	605	Missense	distal	7	no	189.498	188.297	EPSD	COSMIC	187.474	Down-regulation
Other_IKK_CHUK_ST	Q9Y6Q9	NCOA3	O15111	CHUK	S628	R632W	632	Missense	distal	4	no	190.274	185.611	EPSD	COSMIC	187.474	Loss
Other_IKK_CHUK_ST	Q9Y6Q9	NCOA3	O15111	CHUK	S640	S636F	636	Missense	distal	-4	no	275.702	248.033	EPSD	COSMIC	187.474	Down-regulation
Other_IKK_CHUK_ST	Q9Y6Q9	NCOA3	O15111	CHUK	S644	E648K	648	Missense	distal	4	no	208.303	213.627	EPSD	COSMIC	187.474	Up-regulation
Other_IKK_CHUK_ST	Q9Y6Q9	NCOA3	O15111	CHUK	S652	E648K	648	Missense	distal	-4	no	183.066	194.832	EPSD	COSMIC	187.474	Gain
Other_IKK_CHUK_ST	Q9Y6Q9	NCOA3	O15111	CHUK	S715	K708T	708	Missense	distal	-7	no	202.517	201.365	EPSD	COSMIC	187.474	Down-regulation
Other_IKK_CHUK_ST	Q9Y6Q9	NCOA3	O15111	CHUK	S715	G719E	719	Missense	distal	4	no	202.517	205.497	EPSD	COSMIC	187.474	Up-regulation
Other_IKK_CHUK_ST	Q9Y6Q9	NCOA3	O15111	CHUK	S841	S842L	842	Missense	proximal	1	no	174.830	194.304	EPSD	COSMIC	187.474	Gain
Other_IKK_CHUK_ST	Q9Y6Q9	NCOA3	O15111	CHUK	S857	S863F	863	Missense	distal	6	no	229.164	234.178	PhosphoSitePlus	COSMIC	187.474	Up-regulation
Other_IKK_CHUK_ST	Q9Y6Q9	NCOA3	O15111	CHUK	S857	P850S	850	Missense	distal	-7	no	229.164	232.698	PhosphoSitePlus	COSMIC	187.474	Up-regulation
Other_IKK_CHUK_ST	Q9Y6Q9	NCOA3	O15111	CHUK	S857	S857C	857	Missense	central	0	yes	229.164	0.000	PhosphoSitePlus	COSMIC	187.474	Loss
Other_IKK_CHUK_ST	Q9Y6Q9	NCOA3	O15111	CHUK	S916	P923Q	923	Missense	distal	7	no	194.919	187.191	EPSD	COSMIC	187.474	Loss
Other_IKK_CHUK_ST	Q9Y6Q9	NCOA3	O15111	CHUK	S916	L922S	922	Missense	distal	6	no	194.919	193.386	EPSD	COSMIC	187.474	Down-regulation
Other_IKK_CHUK_ST	Q9Y6Q9	NCOA3	O15111	CHUK	S916	D919V	919	Missense	distal	3	no	194.919	116.590	EPSD	COSMIC	187.474	Loss
Other_IKK_CHUK_ST	Q9Y6Q9	NCOA3	O15111	CHUK	S916	W920R	920	Missense	distal	4	no	194.919	199.582	EPSD	COSMIC	187.474	Up-regulation
Other_IKK_CHUK_ST	Q9Y6Q9	NCOA3	O15111	CHUK	S1033	R1031M	1031	Missense	proximal	-2	no	230.885	218.721	EPSD	COSMIC	187.474	Down-regulation
Other_IKK_CHUK_ST	Q9Y6Q9	NCOA3	O15111	CHUK	S1033	L1034M	1034	Missense	proximal	1	no	230.885	225.685	EPSD	COSMIC	187.474	Down-regulation
Other_IKK_CHUK_ST	Q9Y6Q9	NCOA3	O15111	CHUK	S1033	L1029V	1029	Missense	distal	-4	no	230.885	245.723	EPSD	COSMIC	187.474	Up-regulation
Other_IKK_CHUK_ST	Q9Y6Q9	NCOA3	O15111	CHUK	S1033	R1027M	1027	Missense	distal	-6	no	230.885	227.745	EPSD	COSMIC	187.474	Down-regulation
Other_IKK_CHUK_ST	Q9Y6Q9	NCOA3	O15111	CHUK	S1033	L1029M	1029	Missense	distal	-4	no	230.885	250.291	EPSD	COSMIC	187.474	Up-regulation
Other_IKK_CHUK_ST	Q9Y6Q9	NCOA3	O15111	CHUK	S1330	S1330G	1330	Missense	central	0	yes	194.924	0.000	EPSD	COSMIC	187.474	Loss
Other_IKK_CHUK_ST	Q9Y6Q9	NCOA3	O15111	CHUK	S1330	P1331L	1331	Missense	proximal	1	no	194.924	208.997	EPSD	COSMIC	187.474	Up-regulation
Other_IKK_CHUK_ST	Q9Y6Q9	NCOA3	O15111	CHUK	S1338	R1339I	1339	Missense	proximal	1	no	202.883	220.993	EPSD	COSMIC	187.474	Up-regulation
Other_IKK_CHUK_ST	Q9Y6Q9	NCOA3	O15111	CHUK	S1338	P1331L	1331	Missense	distal	-7	no	202.883	203.445	EPSD	COSMIC	187.474	Up-regulation
Other_IKK_CHUK_ST	Q99558	MAP3K14	O15111	CHUK	S261	P259S	259	Missense	proximal	-2	no	173.828	198.633	EPSD	COSMIC	187.474	Gain
Other_IKK_CHUK_ST	Q99558	MAP3K14	O15111	CHUK	S410	R408T	408	Missense	proximal	-2	no	193.756	186.290	EPSD	COSMIC	187.474	Loss
Other_IKK_CHUK_ST	Q99558	MAP3K14	O15111	CHUK	S410	S410F	410	Missense	central	0	yes	193.756	0.000	EPSD	COSMIC	187.474	Loss
Other_IKK_CHUK_ST	Q99558	MAP3K14	O15111	CHUK	S410	R408I	408	Missense	proximal	-2	no	193.756	191.347	EPSD	COSMIC	187.474	Down-regulation
Other_IKK_CHUK_ST	Q99558	MAP3K14	O15111	CHUK	S549	D544H	544	Missense	distal	-5	no	231.550	211.848	EPSD	COSMIC	187.474	Down-regulation
Other_IKK_CHUK_ST	Q99558	MAP3K14	O15111	CHUK	S549	L546M	546	Missense	distal	-3	no	231.550	224.150	EPSD	COSMIC	187.474	Down-regulation
Other_IKK_CHUK_ST	P19838	NFKB1	O15111	CHUK	S74	P70H	70	Missense	distal	-4	no	243.762	228.488	EPSD	COSMIC	187.474	Down-regulation
Other_IKK_CHUK_ST	P19838	NFKB1	O15111	CHUK	S301	H306D	306	Missense	distal	5	no	190.288	186.756	EPSD	COSMIC	187.474	Loss
Other_IKK_CHUK_ST	P19838	NFKB1	O15111	CHUK	S301	S301P	301	Missense	central	0	yes	190.288	0.000	EPSD	COSMIC	187.474	Loss
Other_IKK_CHUK_ST	P19838	NFKB1	O15111	CHUK	S373	P368L	368	Missense	distal	-5	no	212.594	208.651	EPSD	COSMIC	187.474	Down-regulation
Other_IKK_CHUK_ST	P19838	NFKB1	O15111	CHUK	S373	L366F	366	Missense	distal	-7	no	212.594	211.743	EPSD	COSMIC	187.474	Down-regulation
Other_IKK_CHUK_ST	P19838	NFKB1	O15111	CHUK	S373	G375S	375	Missense	proximal	2	no	212.594	208.105	EPSD	COSMIC	187.474	Down-regulation
Other_IKK_CHUK_ST	P19838	NFKB1	O15111	CHUK	S373	G376S	376	Missense	distal	3	no	212.594	200.674	EPSD	COSMIC;CCLE	187.474	Down-regulation
Other_IKK_CHUK_ST	P19838	NFKB1	O15111	CHUK	S855	P852H	852	Missense	distal	-3	no	196.495	188.914	EPSD	COSMIC	187.474	Down-regulation
Other_IKK_CHUK_ST	P19838	NFKB1	O15111	CHUK	T857	P852H	852	Missense	distal	-5	no	198.004	195.165	EPSD	COSMIC	187.474	Down-regulation
Other_IKK_CHUK_ST	P19838	NFKB1	O15111	CHUK	S899	S893P	893	Missense	distal	-6	no	185.834	192.240	EPSD	COSMIC	187.474	Gain
Other_IKK_CHUK_ST	P19838	NFKB1	O15111	CHUK	S899	S893Y	893	Missense	distal	-6	no	185.834	187.943	EPSD	COSMIC	187.474	Gain
Other_IKK_CHUK_ST	P19838	NFKB1	O15111	CHUK	S899	S893F	893	Missense	distal	-6	no	185.834	189.846	EPSD	COSMIC	187.474	Gain
Other_IKK_CHUK_ST	P19838	NFKB1	O15111	CHUK	S903	S910F	910	Missense	distal	7	no	199.900	206.823	EPSD	COSMIC	187.474	Up-regulation
Other_IKK_CHUK_ST	P19838	NFKB1	O15111	CHUK	S903	P905S	905	Missense	proximal	2	no	199.900	196.072	EPSD	COSMIC	187.474	Down-regulation
Other_IKK_CHUK_ST	P19838	NFKB1	O15111	CHUK	S923	E930K	930	Missense	distal	7	no	239.182	241.378	PhosphoSitePlus;EPSD	COSMIC	187.474	Up-regulation
Other_IKK_CHUK_ST	P19838	NFKB1	O15111	CHUK	S927	R934H	934	Missense	distal	7	no	231.963	228.599	EPSD;PhosphoSitePlus	COSMIC	187.474	Down-regulation
Other_IKK_CHUK_ST	P19838	NFKB1	O15111	CHUK	S927	E930K	930	Missense	distal	3	no	231.963	232.684	EPSD;PhosphoSitePlus	COSMIC	187.474	Up-regulation
Other_IKK_CHUK_ST	P19838	NFKB1	O15111	CHUK	S932	R934H	934	Missense	proximal	2	no	220.499	222.346	EPSD;PhosphoSitePlus	COSMIC	187.474	Up-regulation
Other_IKK_CHUK_ST	P19838	NFKB1	O15111	CHUK	S932	E930K	930	Missense	proximal	-2	no	220.499	225.359	EPSD;PhosphoSitePlus	COSMIC	187.474	Up-regulation
Other_IKK_CHUK_ST	P19838	NFKB1	O15111	CHUK	S932	T939I	939	Missense	distal	7	no	220.499	214.011	EPSD;PhosphoSitePlus	COSMIC	187.474	Down-regulation
Other_IKK_CHUK_ST	P19838	NFKB1	O15111	CHUK	S941	R934H	934	Missense	distal	-7	no	219.876	222.220	EPSD	COSMIC	187.474	Up-regulation
Other_IKK_CHUK_ST	P19838	NFKB1	O15111	CHUK	S941	S947L	947	Missense	distal	6	no	219.876	221.409	EPSD	COSMIC	187.474	Up-regulation
Other_IKK_CHUK_ST	P19838	NFKB1	O15111	CHUK	S941	T939I	939	Missense	proximal	-2	no	219.876	224.932	EPSD	COSMIC	187.474	Up-regulation
Other_IKK_CHUK_ST	P03372	ESR1	O15111	CHUK	S118	P113L	113	Missense	distal	-5	no	231.360	227.418	PhosphoSitePlus	COSMIC	187.474	Down-regulation
Other_IKK_CHUK_ST	P03372	ESR1	O15111	CHUK	S118	P113Q	113	Missense	distal	-5	no	231.360	228.271	PhosphoSitePlus	COSMIC	187.474	Down-regulation
Other_IKK_CHUK_ST	P03372	ESR1	O15111	CHUK	S118	L117Q	117	Missense	proximal	-1	no	231.360	229.452	PhosphoSitePlus	COSMIC	187.474	Down-regulation
Other_IKK_CHUK_ST	P03372	ESR1	O15111	CHUK	S118	H112L	112	Missense	distal	-6	no	231.360	221.730	PhosphoSitePlus	COSMIC	187.474	Down-regulation
Other_IKK_CHUK_ST	P03372	ESR1	O15111	CHUK	S118	S118P	118	Missense	central	0	yes	231.360	0.000	PhosphoSitePlus	COSMIC	187.474	Loss
Other_IKK_CHUK_ST	P03372	ESR1	O15111	CHUK	S167	G172R	172	Missense	distal	5	no	203.246	205.652	EPSD	COSMIC	187.474	Up-regulation
Other_IKK_CHUK_ST	P03372	ESR1	O15111	CHUK	S167	M174I	174	Missense	distal	7	no	203.246	199.508	EPSD	COSMIC	187.474	Down-regulation
Other_IKK_CHUK_ST	P03372	ESR1	O15111	CHUK	S167	D170Y	170	Missense	distal	3	no	203.246	147.966	EPSD	COSMIC	187.474	Loss
Other_IKK_CHUK_ST	P03372	ESR1	O15111	CHUK	S167	G160D	160	Missense	distal	-7	no	203.246	203.868	EPSD	COSMIC	187.474	Up-regulation
Other_IKK_CHUK_ST	P03372	ESR1	O15111	CHUK	S201	K206T	206	Missense	distal	5	no	213.048	210.810	EPSD	COSMIC	187.474	Down-regulation
Other_IKK_CHUK_ST	P03372	ESR1	O15111	CHUK	S201	E203V	203	Missense	proximal	2	no	213.048	211.752	EPSD	COSMIC	187.474	Down-regulation
Other_IKK_CHUK_ST	P03372	ESR1	O15111	CHUK	S329	P325S	325	Missense	distal	-4	no	181.772	189.389	EPSD	COSMIC	187.474	Gain
Other_IKK_CHUK_ST	P03372	ESR1	O15111	CHUK	S329	P324S	324	Missense	distal	-5	no	181.772	190.426	EPSD	COSMIC	187.474	Gain
Other_IKK_CHUK_ST	P03372	ESR1	O15111	CHUK	S341	S338G	338	Missense	distal	-3	no	209.841	223.849	EPSD	COSMIC	187.474	Up-regulation
Other_IKK_CHUK_ST	P03372	ESR1	O15111	CHUK	S341	S338R	338	Missense	distal	-3	no	209.841	228.819	EPSD	COSMIC	187.474	Up-regulation
Other_IKK_CHUK_ST	P03372	ESR1	O15111	CHUK	S341	T347I	347	Missense	distal	6	no	209.841	216.379	EPSD	COSMIC	187.474	Up-regulation
Other_IKK_CHUK_ST	P03372	ESR1	O15111	CHUK	S341	M343L	343	Missense	proximal	2	no	209.841	207.505	EPSD	COSMIC	187.474	Down-regulation
Other_IKK_CHUK_ST	P03372	ESR1	O15111	CHUK	S573	S578Y	578	Missense	distal	5	no	190.752	193.367	EPSD	COSMIC	187.474	Up-regulation
Other_IKK_CHUK_ST	P03372	ESR1	O15111	CHUK	S575	S578Y	578	Missense	distal	3	no	204.263	188.642	EPSD	COSMIC	187.474	Down-regulation
Other_IKK_CHUK_ST	P03372	ESR1	O15111	CHUK	S578	T585S	585	Missense	distal	7	no	220.288	212.412	EPSD	COSMIC	187.474	Down-regulation
Other_IKK_CHUK_ST	P03372	ESR1	O15111	CHUK	S578	S578Y	578	Missense	central	0	yes	220.288	0.000	EPSD	COSMIC	187.474	Loss
Other_IKK_CHUK_ST	Q9BUZ4	TRAF4	O15111	CHUK	S426	G433S	433	Missense	distal	7	no	230.698	218.126	PhosphoSitePlus	COSMIC	187.474	Down-regulation
Other_IKK_CHUK_ST	P25963	NFKBIA	O15111	CHUK	S32	M37K	37	Missense	distal	5	no	241.183	239.764	EPSD;PhosphoSitePlus	COSMIC	187.474	Down-regulation
Other_IKK_CHUK_ST	P25963	NFKBIA	O15111	CHUK	S32	S36P	36	Missense	distal	4	no	241.183	239.253	EPSD;PhosphoSitePlus	COSMIC	187.474	Down-regulation
Other_IKK_CHUK_ST	P25963	NFKBIA	O15111	CHUK	S32	S32N	32	Missense	central	0	yes	241.183	0.000	EPSD;PhosphoSitePlus	COSMIC	187.474	Loss
Other_IKK_CHUK_ST	P25963	NFKBIA	O15111	CHUK	S36	M37K	37	Missense	proximal	1	no	284.901	275.956	PhosphoSitePlus;EPSD	COSMIC	187.474	Down-regulation
Other_IKK_CHUK_ST	P25963	NFKBIA	O15111	CHUK	S36	E40D	40	Missense	distal	4	no	284.901	286.146	PhosphoSitePlus;EPSD	COSMIC	187.474	Up-regulation
Other_IKK_CHUK_ST	P25963	NFKBIA	O15111	CHUK	S36	E43K	43	Missense	distal	7	no	284.901	287.097	PhosphoSitePlus;EPSD	COSMIC	187.474	Up-regulation
Other_IKK_CHUK_ST	P25963	NFKBIA	O15111	CHUK	S36	S36P	36	Missense	central	0	yes	284.901	0.000	PhosphoSitePlus;EPSD	COSMIC	187.474	Loss
Other_IKK_CHUK_ST	P25963	NFKBIA	O15111	CHUK	S36	E43Q	43	Missense	distal	7	no	284.901	278.988	PhosphoSitePlus;EPSD	COSMIC	187.474	Down-regulation
Other_IKK_CHUK_ST	P25963	NFKBIA	O15111	CHUK	S36	S32N	32	Missense	distal	-4	no	284.901	288.012	PhosphoSitePlus;EPSD	COSMIC	187.474	Up-regulation
Other_IKK_CHUK_ST	P25963	NFKBIA	O15111	CHUK	S174	N180Y	180	Missense	distal	6	no	218.059	213.807	EPSD	COSMIC	187.474	Down-regulation
Other_IKK_CHUK_ST	P25963	NFKBIA	O15111	CHUK	S293	T291K	291	Missense	proximal	-2	no	198.244	197.437	EPSD	COSMIC	187.474	Down-regulation
Other_IKK_CHUK_ST	P25963	NFKBIA	O15111	CHUK	S293	T291P	291	Missense	proximal	-2	no	198.244	170.201	EPSD	COSMIC	187.474	Loss
Other_IKK_CHUK_ST	P25963	NFKBIA	O15111	CHUK	S293	E287V	287	Missense	distal	-6	no	198.244	197.587	EPSD	COSMIC	187.474	Down-regulation
Other_IKK_CHUK_ST	P25963	NFKBIA	O15111	CHUK	S293	Y289C	289	Missense	distal	-4	no	198.244	183.496	EPSD	COSMIC	187.474	Loss
Other_IKK_CHUK_ST	Q9Y261	FOXA2	O15111	CHUK	S107	S107G	107	Missense	central	0	yes	239.062	0.000	PhosphoSitePlus;EPSD	COSMIC	187.474	Loss
Other_IKK_CHUK_ST	Q9Y261	FOXA2	O15111	CHUK	S107	P112L	112	Missense	distal	5	no	239.062	236.288	PhosphoSitePlus;EPSD	COSMIC	187.474	Down-regulation
Other_IKK_CHUK_ST	Q9Y261	FOXA2	O15111	CHUK	S107	S109N	109	Missense	proximal	2	no	239.062	242.019	PhosphoSitePlus;EPSD	COSMIC	187.474	Up-regulation
Other_IKK_CHUK_ST	Q9Y261	FOXA2	O15111	CHUK	S111	A117V	117	Missense	distal	6	no	231.883	239.397	EPSD;PhosphoSitePlus	COSMIC	187.474	Up-regulation
Other_IKK_CHUK_ST	Q9Y261	FOXA2	O15111	CHUK	S111	S107G	107	Missense	distal	-4	no	231.883	221.318	EPSD;PhosphoSitePlus	COSMIC	187.474	Down-regulation
Other_IKK_CHUK_ST	Q9Y261	FOXA2	O15111	CHUK	S111	P112L	112	Missense	proximal	1	no	231.883	245.957	EPSD;PhosphoSitePlus	COSMIC	187.474	Up-regulation
Other_IKK_CHUK_ST	Q9Y261	FOXA2	O15111	CHUK	S111	S109N	109	Missense	proximal	-2	no	231.883	223.670	EPSD;PhosphoSitePlus	COSMIC	187.474	Down-regulation
Other_IKK_CHUK_ST	Q9Y261	FOXA2	O15111	CHUK	S212	I207L	207	Missense	distal	-5	no	181.804	189.954	EPSD	COSMIC	187.474	Gain
Other_IKK_CHUK_ST	Q9Y261	FOXA2	O15111	CHUK	S212	I207M	207	Missense	distal	-5	no	181.804	196.563	EPSD	COSMIC	187.474	Gain
Other_IKK_CHUK_ST	Q9Y261	FOXA2	O15111	CHUK	S212	I207T	207	Missense	distal	-5	no	181.804	196.869	EPSD	COSMIC	187.474	Gain
Other_IKK_CHUK_ST	Q9Y261	FOXA2	O15111	CHUK	S338	S331G	331	Missense	distal	-7	no	210.024	208.986	EPSD	COSMIC	187.474	Down-regulation
Other_IKK_CHUK_ST	Q9Y261	FOXA2	O15111	CHUK	S338	P333S	333	Missense	distal	-5	no	210.024	218.678	EPSD	COSMIC	187.474	Up-regulation
Other_IKK_CHUK_ST	Q9Y261	FOXA2	O15111	CHUK	S338	P339S	339	Missense	proximal	1	no	210.024	204.623	EPSD	COSMIC	187.474	Down-regulation
Other_IKK_CHUK_ST	Q00653	NFKB2	O15111	CHUK	S70	G67D	67	Missense	distal	-3	no	225.266	216.216	EPSD	COSMIC	187.474	Down-regulation
Other_IKK_CHUK_ST	Q00653	NFKB2	O15111	CHUK	S70	P66S	66	Missense	distal	-4	no	225.266	232.883	EPSD	COSMIC	187.474	Up-regulation
Other_IKK_CHUK_ST	Q00653	NFKB2	O15111	CHUK	S70	R74Q	74	Missense	distal	4	no	225.266	223.441	EPSD	COSMIC;CCLE	187.474	Down-regulation
Other_IKK_CHUK_ST	Q00653	NFKB2	O15111	CHUK	S70	A68V	68	Missense	proximal	-2	no	225.266	207.197	EPSD	COSMIC	187.474	Down-regulation
Other_IKK_CHUK_ST	Q00653	NFKB2	O15111	CHUK	S99	P102R	102	Missense	distal	3	no	219.724	179.623	EPSD;PhosphoSitePlus	COSMIC	187.474	Loss
Other_IKK_CHUK_ST	Q00653	NFKB2	O15111	CHUK	S108	P102R	102	Missense	distal	-6	no	258.479	258.979	EPSD;PhosphoSitePlus	COSMIC	187.474	Up-regulation
Other_IKK_CHUK_ST	Q00653	NFKB2	O15111	CHUK	S277	V281L	281	Missense	distal	4	no	199.977	200.116	EPSD	COSMIC	187.474	Up-regulation
Other_IKK_CHUK_ST	Q00653	NFKB2	O15111	CHUK	S427	C432W	432	Missense	distal	5	no	194.354	194.395	EPSD	COSMIC	187.474	Up-regulation
Other_IKK_CHUK_ST	Q00653	NFKB2	O15111	CHUK	S713	G719W	719	Missense	distal	6	no	185.701	196.529	EPSD	COSMIC	187.474	Gain
Other_IKK_CHUK_ST	Q00653	NFKB2	O15111	CHUK	S717	G719W	719	Missense	proximal	2	no	199.018	200.045	EPSD	COSMIC	187.474	Up-regulation
Other_IKK_CHUK_ST	Q00653	NFKB2	O15111	CHUK	S812	P813L	813	Missense	proximal	1	no	194.115	208.188	EPSD	COSMIC	187.474	Up-regulation
Other_IKK_CHUK_ST	Q00653	NFKB2	O15111	CHUK	S812	R819C	819	Missense	distal	7	no	194.115	192.338	EPSD	COSMIC;CCLE	187.474	Down-regulation
Other_IKK_CHUK_ST	Q00653	NFKB2	O15111	CHUK	S814	P813L	813	Missense	proximal	-1	no	200.595	202.587	EPSD	COSMIC	187.474	Up-regulation
Other_IKK_CHUK_ST	Q00653	NFKB2	O15111	CHUK	S814	R819C	819	Missense	distal	5	no	200.595	205.091	EPSD	COSMIC;CCLE	187.474	Up-regulation
Other_IKK_CHUK_ST	Q00653	NFKB2	O15111	CHUK	S816	R819C	819	Missense	distal	3	no	183.025	188.262	EPSD	COSMIC;CCLE	187.474	Gain
Other_IKK_CHUK_ST	Q00653	NFKB2	O15111	CHUK	S866	S872T	872	Missense	distal	6	no	196.741	191.460	EPSD;PhosphoSitePlus	COSMIC	187.474	Down-regulation
Other_IKK_CHUK_ST	Q01201	RELB	O15111	CHUK	S48	S50R	50	Missense	proximal	2	no	188.722	190.083	EPSD	COSMIC	187.474	Up-regulation
Other_IKK_CHUK_ST	Q01201	RELB	O15111	CHUK	S116	P123Q	123	Missense	distal	7	no	228.504	220.776	EPSD	COSMIC	187.474	Down-regulation
Other_IKK_CHUK_ST	Q01201	RELB	O15111	CHUK	S116	C109S	109	Missense	distal	-7	no	228.504	234.078	EPSD	COSMIC	187.474	Up-regulation
Other_IKK_CHUK_ST	Q01201	RELB	O15111	CHUK	S116	P121Q	121	Missense	distal	5	no	228.504	223.275	EPSD	COSMIC;CCLE	187.474	Down-regulation
Other_IKK_CHUK_ST	Q01201	RELB	O15111	CHUK	S151	G150S	150	Missense	proximal	-1	no	254.845	256.420	EPSD	COSMIC	187.474	Up-regulation
Other_IKK_CHUK_ST	Q01201	RELB	O15111	CHUK	S151	R147H	147	Missense	distal	-4	no	254.845	251.203	EPSD	COSMIC;CCLE	187.474	Down-regulation
Other_IKK_CHUK_ST	Q01201	RELB	O15111	CHUK	S151	E145K	145	Missense	distal	-6	no	254.845	257.589	EPSD	COSMIC	187.474	Up-regulation
Other_IKK_CHUK_ST	Q01201	RELB	O15111	CHUK	S151	G154R	154	Missense	distal	3	no	254.845	204.401	EPSD	COSMIC;GDSC;CCLE	187.474	Down-regulation
Other_IKK_CHUK_ST	Q01201	RELB	O15111	CHUK	S151	E145Q	145	Missense	distal	-6	no	254.845	253.692	EPSD	COSMIC	187.474	Down-regulation
Other_IKK_CHUK_ST	Q01201	RELB	O15111	CHUK	S221	H215R	215	Missense	distal	-6	no	208.846	207.624	EPSD	COSMIC	187.474	Down-regulation
Other_IKK_CHUK_ST	Q01201	RELB	O15111	CHUK	S221	S221I	221	Missense	central	0	yes	208.846	0.000	EPSD	COSMIC	187.474	Loss
Other_IKK_CHUK_ST	Q01201	RELB	O15111	CHUK	S221	P214S	214	Missense	distal	-7	no	208.846	212.380	EPSD	COSMIC	187.474	Up-regulation
Other_IKK_CHUK_ST	Q01201	RELB	O15111	CHUK	S221	H220Y	220	Missense	proximal	-1	no	208.846	208.483	EPSD	COSMIC	187.474	Down-regulation
Other_IKK_CHUK_ST	Q01201	RELB	O15111	CHUK	S221	R219W	219	Missense	proximal	-2	no	208.846	193.194	EPSD	COSMIC	187.474	Down-regulation
Other_IKK_CHUK_ST	Q01201	RELB	O15111	CHUK	S254	D248V	248	Missense	distal	-6	no	214.747	217.316	EPSD	COSMIC	187.474	Up-regulation
Other_IKK_CHUK_ST	Q01201	RELB	O15111	CHUK	S254	P249L	249	Missense	distal	-5	no	214.747	210.805	EPSD	COSMIC	187.474	Down-regulation
Other_IKK_CHUK_ST	Q01201	RELB	O15111	CHUK	S254	Y250N	250	Missense	distal	-4	no	214.747	230.637	EPSD	COSMIC	187.474	Up-regulation
Other_IKK_CHUK_ST	Q01201	RELB	O15111	CHUK	S254	P249T	249	Missense	distal	-5	no	214.747	217.720	EPSD	COSMIC	187.474	Up-regulation
Other_IKK_CHUK_ST	Q01201	RELB	O15111	CHUK	S254	V261L	261	Missense	distal	7	no	214.747	203.650	EPSD	COSMIC	187.474	Down-regulation
Other_IKK_CHUK_ST	Q01201	RELB	O15111	CHUK	S472	D465Y	465	Missense	distal	-7	no	230.199	227.054	PhosphoSitePlus	COSMIC	187.474	Down-regulation
Other_IKK_CHUK_ST	Q01201	RELB	O15111	CHUK	S472	S472F	472	Missense	central	0	yes	230.199	0.000	PhosphoSitePlus	COSMIC	187.474	Loss
Other_IKK_CHUK_ST	Q01201	RELB	O15111	CHUK	S573	L571I	571	Missense	proximal	-2	no	224.036	220.788	EPSD	COSMIC	187.474	Down-regulation
Other_IKK_CHUK_ST	Q676U5	ATG16L1	O15111	CHUK	S278	N281T	281	Missense	distal	3	no	257.874	251.318	PhosphoSitePlus	COSMIC	187.474	Down-regulation
Other_IKK_CHUK_ST	Q676U5	ATG16L1	O15111	CHUK	S278	R285I	285	Missense	distal	7	no	257.874	247.564	PhosphoSitePlus	COSMIC	187.474	Down-regulation
Other_IKK_CHUK_ST	Q676U5	ATG16L1	O15111	CHUK	S278	G284W	284	Missense	distal	6	no	257.874	268.702	PhosphoSitePlus	COSMIC	187.474	Up-regulation
Other_IKK_CHUK_ST	Q676U5	ATG16L1	O15111	CHUK	S331	S334F	334	Missense	distal	3	no	214.670	180.411	EPSD	COSMIC	187.474	Loss
Other_IKK_CHUK_ST	Q676U5	ATG16L1	O15111	CHUK	S331	P332L	332	Missense	proximal	1	no	214.670	228.743	EPSD	COSMIC	187.474	Up-regulation
Other_IKK_CHUK_ST	P35222	CTNNB1	O15111	CHUK	S29	I35T	35	Missense	distal	6	no	194.361	187.824	EPSD	COSMIC	187.474	Down-regulation
Other_IKK_CHUK_ST	P35222	CTNNB1	O15111	CHUK	S29	Q28E	28	Missense	proximal	-1	no	194.361	194.478	EPSD	COSMIC	187.474	Up-regulation
Other_IKK_CHUK_ST	P35222	CTNNB1	O15111	CHUK	S29	D32E	32	Missense	distal	3	no	194.361	148.595	EPSD	COSMIC	187.474	Loss
Other_IKK_CHUK_ST	P35222	CTNNB1	O15111	CHUK	S29	H36R	36	Missense	distal	7	no	194.361	197.725	EPSD	COSMIC	187.474	Up-regulation
Other_IKK_CHUK_ST	P35222	CTNNB1	O15111	CHUK	S29	G34L	34	Missense	distal	5	no	194.361	195.574	EPSD	COSMIC	187.474	Up-regulation
Other_IKK_CHUK_ST	P35222	CTNNB1	O15111	CHUK	S29	V22I	22	Missense	distal	-7	no	194.361	195.881	EPSD	COSMIC	187.474	Up-regulation
Other_IKK_CHUK_ST	P35222	CTNNB1	O15111	CHUK	S29	S33L	33	Missense	distal	4	no	194.361	193.222	EPSD	COSMIC;CCLE	187.474	Down-regulation
Other_IKK_CHUK_ST	P35222	CTNNB1	O15111	CHUK	S29	S29P	29	Missense	central	0	yes	194.361	0.000	EPSD	COSMIC	187.474	Loss
Other_IKK_CHUK_ST	P35222	CTNNB1	O15111	CHUK	S29	L31P	31	Missense	proximal	2	no	194.361	198.522	EPSD	COSMIC	187.474	Up-regulation
Other_IKK_CHUK_ST	P35222	CTNNB1	O15111	CHUK	S29	Q27H	27	Missense	proximal	-2	no	194.361	178.492	EPSD	COSMIC	187.474	Loss
Other_IKK_CHUK_ST	P35222	CTNNB1	O15111	CHUK	S29	S33N	33	Missense	distal	4	no	194.361	192.949	EPSD	COSMIC	187.474	Down-regulation
Other_IKK_CHUK_ST	P35222	CTNNB1	O15111	CHUK	S29	H36Y	36	Missense	distal	7	no	194.361	190.756	EPSD	COSMIC	187.474	Down-regulation
Other_IKK_CHUK_ST	P35222	CTNNB1	O15111	CHUK	S29	S23N	23	Missense	distal	-6	no	194.361	198.283	EPSD	COSMIC	187.474	Up-regulation
Other_IKK_CHUK_ST	P35222	CTNNB1	O15111	CHUK	S29	S29F	29	Missense	central	0	yes	194.361	0.000	EPSD	COSMIC	187.474	Loss
Other_IKK_CHUK_ST	P35222	CTNNB1	O15111	CHUK	S29	Y30C	30	Missense	proximal	1	no	194.361	198.096	EPSD	COSMIC	187.474	Up-regulation
Other_IKK_CHUK_ST	P35222	CTNNB1	O15111	CHUK	S29	S29Y	29	Missense	central	0	yes	194.361	0.000	EPSD	COSMIC	187.474	Loss
Other_IKK_CHUK_ST	P35222	CTNNB1	O15111	CHUK	S29	S23R	23	Missense	distal	-6	no	194.361	201.267	EPSD	COSMIC	187.474	Up-regulation
Other_IKK_CHUK_ST	P35222	CTNNB1	O15111	CHUK	S29	H24Y	24	Missense	distal	-5	no	194.361	199.048	EPSD	COSMIC	187.474	Up-regulation
Other_IKK_CHUK_ST	P35222	CTNNB1	O15111	CHUK	S29	W25R	25	Missense	distal	-4	no	194.361	208.811	EPSD	COSMIC	187.474	Up-regulation
Other_IKK_CHUK_ST	P35222	CTNNB1	O15111	CHUK	S29	V22A	22	Missense	distal	-7	no	194.361	194.886	EPSD	COSMIC	187.474	Up-regulation
Other_IKK_CHUK_ST	P35222	CTNNB1	O15111	CHUK	S29	I35M	35	Missense	distal	6	no	194.361	196.286	EPSD	COSMIC	187.474	Up-regulation
Other_IKK_CHUK_ST	P35222	CTNNB1	O15111	CHUK	S29	W25L	25	Missense	distal	-4	no	194.361	192.210	EPSD	COSMIC	187.474	Down-regulation
Other_IKK_CHUK_ST	P35222	CTNNB1	O15111	CHUK	S29	H24Q	24	Missense	distal	-5	no	194.361	194.111	EPSD	COSMIC	187.474	Down-regulation
Other_IKK_CHUK_ST	P35222	CTNNB1	O15111	CHUK	S29	S23G	23	Missense	distal	-6	no	194.361	196.214	EPSD	COSMIC	187.474	Up-regulation
Other_IKK_CHUK_ST	P35222	CTNNB1	O15111	CHUK	S29	V22G	22	Missense	distal	-7	no	194.361	197.501	EPSD	COSMIC	187.474	Up-regulation
Other_IKK_CHUK_ST	P35222	CTNNB1	O15111	CHUK	S29	S29A	29	Missense	central	0	yes	194.361	0.000	EPSD	COSMIC	187.474	Loss
Other_IKK_CHUK_ST	P35222	CTNNB1	O15111	CHUK	S29	G34A	34	Missense	distal	5	no	194.361	193.589	EPSD	COSMIC	187.474	Down-regulation
Other_IKK_CHUK_ST	P35222	CTNNB1	O15111	CHUK	S29	L31W	31	Missense	proximal	2	no	194.361	200.210	EPSD	COSMIC	187.474	Up-regulation
Other_IKK_CHUK_ST	P35222	CTNNB1	O15111	CHUK	S29	G34I	34	Missense	distal	5	no	194.361	190.909	EPSD	COSMIC	187.474	Down-regulation
Other_IKK_CHUK_ST	P35222	CTNNB1	O15111	CHUK	S29	I35N	35	Missense	distal	6	no	194.361	196.576	EPSD	COSMIC	187.474	Up-regulation
Other_IKK_CHUK_ST	P35222	CTNNB1	O15111	CHUK	S29	D32C	32	Missense	distal	3	no	194.361	121.415	EPSD	COSMIC	187.474	Loss
Other_IKK_CHUK_ST	P35222	CTNNB1	O15111	CHUK	S29	Y30S	30	Missense	proximal	1	no	194.361	195.056	EPSD	COSMIC	187.474	Up-regulation
Other_IKK_CHUK_ST	P35222	CTNNB1	O15111	CHUK	S29	L31M	31	Missense	proximal	2	no	194.361	196.698	EPSD	COSMIC	187.474	Up-regulation
Other_IKK_CHUK_ST	P35222	CTNNB1	O15111	CHUK	S29	H24R	24	Missense	distal	-5	no	194.361	189.476	EPSD	COSMIC	187.474	Down-regulation
Other_IKK_CHUK_ST	P35222	CTNNB1	O15111	CHUK	S29	L31Q	31	Missense	proximal	2	no	194.361	193.387	EPSD	COSMIC	187.474	Down-regulation
Other_IKK_CHUK_ST	P35222	CTNNB1	O15111	CHUK	S29	G34D	34	Missense	distal	5	no	194.361	195.032	EPSD	COSMIC	187.474	Up-regulation
Other_IKK_CHUK_ST	P35222	CTNNB1	O15111	CHUK	S29	Q26R	26	Missense	distal	-3	no	194.361	220.292	EPSD	COSMIC;GDSC;CCLE	187.474	Up-regulation
Other_IKK_CHUK_ST	P35222	CTNNB1	O15111	CHUK	S29	I35K	35	Missense	distal	6	no	194.361	197.193	EPSD	COSMIC	187.474	Up-regulation
Other_IKK_CHUK_ST	P35222	CTNNB1	O15111	CHUK	S29	Q28R	28	Missense	proximal	-1	no	194.361	193.720	EPSD	COSMIC	187.474	Down-regulation
Other_IKK_CHUK_ST	P35222	CTNNB1	O15111	CHUK	S29	D32F	32	Missense	distal	3	no	194.361	120.444	EPSD	COSMIC	187.474	Loss
Other_IKK_CHUK_ST	P35222	CTNNB1	O15111	CHUK	S29	D32X	32	Missense	distal	3	no	194.361	146.100	EPSD	COSMIC	187.474	Loss
Other_IKK_CHUK_ST	P35222	CTNNB1	O15111	CHUK	S29	S33K	33	Missense	distal	4	no	194.361	194.271	EPSD	COSMIC	187.474	Down-regulation
Other_IKK_CHUK_ST	P35222	CTNNB1	O15111	CHUK	S29	I35V	35	Missense	distal	6	no	194.361	200.057	EPSD	COSMIC	187.474	Up-regulation
Other_IKK_CHUK_ST	P35222	CTNNB1	O15111	CHUK	S29	G34C	34	Missense	distal	5	no	194.361	201.264	EPSD	COSMIC	187.474	Up-regulation
Other_IKK_CHUK_ST	P35222	CTNNB1	O15111	CHUK	S29	I35F	35	Missense	distal	6	no	194.361	198.119	EPSD	COSMIC	187.474	Up-regulation
Other_IKK_CHUK_ST	P35222	CTNNB1	O15111	CHUK	S33	A39G	39	Missense	distal	6	no	216.077	213.822	EPSD;PhosphoSitePlus	COSMIC	187.474	Down-regulation
Other_IKK_CHUK_ST	P35222	CTNNB1	O15111	CHUK	S33	G38A	38	Missense	distal	5	no	216.077	215.305	EPSD;PhosphoSitePlus	COSMIC	187.474	Down-regulation
Other_IKK_CHUK_ST	P35222	CTNNB1	O15111	CHUK	S33	T40I	40	Missense	distal	7	no	216.077	209.590	EPSD;PhosphoSitePlus	COSMIC	187.474	Down-regulation
Other_IKK_CHUK_ST	P35222	CTNNB1	O15111	CHUK	S33	I35T	35	Missense	proximal	2	no	216.077	214.865	EPSD;PhosphoSitePlus	COSMIC	187.474	Down-regulation
Other_IKK_CHUK_ST	P35222	CTNNB1	O15111	CHUK	S33	Q28E	28	Missense	distal	-5	no	216.077	210.828	EPSD;PhosphoSitePlus	COSMIC	187.474	Down-regulation
Other_IKK_CHUK_ST	P35222	CTNNB1	O15111	CHUK	S33	D32E	32	Missense	proximal	-1	no	216.077	213.041	EPSD;PhosphoSitePlus	COSMIC	187.474	Down-regulation
Other_IKK_CHUK_ST	P35222	CTNNB1	O15111	CHUK	S33	H36R	36	Missense	distal	3	no	216.077	189.948	EPSD;PhosphoSitePlus	COSMIC	187.474	Down-regulation
Other_IKK_CHUK_ST	P35222	CTNNB1	O15111	CHUK	S33	T40A	40	Missense	distal	7	no	216.077	212.465	EPSD;PhosphoSitePlus	COSMIC	187.474	Down-regulation
Other_IKK_CHUK_ST	P35222	CTNNB1	O15111	CHUK	S33	G34L	34	Missense	proximal	1	no	216.077	235.505	EPSD;PhosphoSitePlus	COSMIC	187.474	Up-regulation
Other_IKK_CHUK_ST	P35222	CTNNB1	O15111	CHUK	S33	S33L	33	Missense	central	0	yes	216.077	0.000	EPSD;PhosphoSitePlus	COSMIC;CCLE	187.474	Loss
Other_IKK_CHUK_ST	P35222	CTNNB1	O15111	CHUK	S33	S29P	29	Missense	distal	-4	no	216.077	208.460	EPSD;PhosphoSitePlus	COSMIC	187.474	Down-regulation
Other_IKK_CHUK_ST	P35222	CTNNB1	O15111	CHUK	S33	L31P	31	Missense	proximal	-2	no	216.077	179.731	EPSD;PhosphoSitePlus	COSMIC	187.474	Loss
Other_IKK_CHUK_ST	P35222	CTNNB1	O15111	CHUK	S33	S37L	37	Missense	distal	4	no	216.077	214.938	EPSD;PhosphoSitePlus	COSMIC	187.474	Down-regulation
Other_IKK_CHUK_ST	P35222	CTNNB1	O15111	CHUK	S33	A39T	39	Missense	distal	6	no	216.077	211.358	EPSD;PhosphoSitePlus	COSMIC	187.474	Down-regulation
Other_IKK_CHUK_ST	P35222	CTNNB1	O15111	CHUK	S33	Q27H	27	Missense	distal	-6	no	216.077	223.087	EPSD;PhosphoSitePlus	COSMIC	187.474	Up-regulation
Other_IKK_CHUK_ST	P35222	CTNNB1	O15111	CHUK	S33	S33N	33	Missense	central	0	yes	216.077	0.000	EPSD;PhosphoSitePlus	COSMIC	187.474	Loss
Other_IKK_CHUK_ST	P35222	CTNNB1	O15111	CHUK	S33	H36Y	36	Missense	distal	3	no	216.077	212.852	EPSD;PhosphoSitePlus	COSMIC	187.474	Down-regulation
Other_IKK_CHUK_ST	P35222	CTNNB1	O15111	CHUK	S33	S29F	29	Missense	distal	-4	no	216.077	188.408	EPSD;PhosphoSitePlus	COSMIC	187.474	Down-regulation
Other_IKK_CHUK_ST	P35222	CTNNB1	O15111	CHUK	S33	Y30C	30	Missense	distal	-3	no	216.077	219.095	EPSD;PhosphoSitePlus	COSMIC	187.474	Up-regulation
Other_IKK_CHUK_ST	P35222	CTNNB1	O15111	CHUK	S33	S29Y	29	Missense	distal	-4	no	216.077	203.298	EPSD;PhosphoSitePlus	COSMIC	187.474	Down-regulation
Other_IKK_CHUK_ST	P35222	CTNNB1	O15111	CHUK	S33	G38P	38	Missense	distal	5	no	216.077	220.064	EPSD;PhosphoSitePlus	COSMIC	187.474	Up-regulation
Other_IKK_CHUK_ST	P35222	CTNNB1	O15111	CHUK	S33	G38D	38	Missense	distal	5	no	216.077	216.748	EPSD;PhosphoSitePlus	COSMIC	187.474	Up-regulation
Other_IKK_CHUK_ST	P35222	CTNNB1	O15111	CHUK	S33	I35M	35	Missense	proximal	2	no	216.077	216.814	EPSD;PhosphoSitePlus	COSMIC	187.474	Up-regulation
Other_IKK_CHUK_ST	P35222	CTNNB1	O15111	CHUK	S33	T40S	40	Missense	distal	7	no	216.077	208.202	EPSD;PhosphoSitePlus	COSMIC	187.474	Down-regulation
Other_IKK_CHUK_ST	P35222	CTNNB1	O15111	CHUK	S33	S29A	29	Missense	distal	-4	no	216.077	199.583	EPSD;PhosphoSitePlus	COSMIC	187.474	Down-regulation
Other_IKK_CHUK_ST	P35222	CTNNB1	O15111	CHUK	S33	G34A	34	Missense	proximal	1	no	216.077	213.974	EPSD;PhosphoSitePlus	COSMIC	187.474	Down-regulation
Other_IKK_CHUK_ST	P35222	CTNNB1	O15111	CHUK	S33	L31W	31	Missense	proximal	-2	no	216.077	199.588	EPSD;PhosphoSitePlus	COSMIC	187.474	Down-regulation
Other_IKK_CHUK_ST	P35222	CTNNB1	O15111	CHUK	S33	G34I	34	Missense	proximal	1	no	216.077	227.864	EPSD;PhosphoSitePlus	COSMIC	187.474	Up-regulation
Other_IKK_CHUK_ST	P35222	CTNNB1	O15111	CHUK	S33	I35N	35	Missense	proximal	2	no	216.077	217.767	EPSD;PhosphoSitePlus	COSMIC	187.474	Up-regulation
Other_IKK_CHUK_ST	P35222	CTNNB1	O15111	CHUK	S33	D32C	32	Missense	proximal	-1	no	216.077	213.058	EPSD;PhosphoSitePlus	COSMIC	187.474	Down-regulation
Other_IKK_CHUK_ST	P35222	CTNNB1	O15111	CHUK	S33	Y30S	30	Missense	distal	-3	no	216.077	210.192	EPSD;PhosphoSitePlus	COSMIC	187.474	Down-regulation
Other_IKK_CHUK_ST	P35222	CTNNB1	O15111	CHUK	S33	L31M	31	Missense	proximal	-2	no	216.077	203.076	EPSD;PhosphoSitePlus	COSMIC	187.474	Down-regulation
Other_IKK_CHUK_ST	P35222	CTNNB1	O15111	CHUK	S33	A39V	39	Missense	distal	6	no	216.077	223.591	EPSD;PhosphoSitePlus	COSMIC	187.474	Up-regulation
Other_IKK_CHUK_ST	P35222	CTNNB1	O15111	CHUK	S33	L31Q	31	Missense	proximal	-2	no	216.077	223.983	EPSD;PhosphoSitePlus	COSMIC	187.474	Up-regulation
Other_IKK_CHUK_ST	P35222	CTNNB1	O15111	CHUK	S33	G34D	34	Missense	proximal	1	no	216.077	224.159	EPSD;PhosphoSitePlus	COSMIC	187.474	Up-regulation
Other_IKK_CHUK_ST	P35222	CTNNB1	O15111	CHUK	S33	Q26R	26	Missense	distal	-7	no	216.077	211.719	EPSD;PhosphoSitePlus	COSMIC;GDSC;CCLE	187.474	Down-regulation
Other_IKK_CHUK_ST	P35222	CTNNB1	O15111	CHUK	S33	S37T	37	Missense	distal	4	no	216.077	212.855	EPSD;PhosphoSitePlus	COSMIC	187.474	Down-regulation
Other_IKK_CHUK_ST	P35222	CTNNB1	O15111	CHUK	S33	I35K	35	Missense	proximal	2	no	216.077	216.189	EPSD;PhosphoSitePlus	COSMIC	187.474	Up-regulation
Other_IKK_CHUK_ST	P35222	CTNNB1	O15111	CHUK	S33	Q28R	28	Missense	distal	-5	no	216.077	211.442	EPSD;PhosphoSitePlus	COSMIC	187.474	Down-regulation
Other_IKK_CHUK_ST	P35222	CTNNB1	O15111	CHUK	S33	D32F	32	Missense	proximal	-1	no	216.077	212.712	EPSD;PhosphoSitePlus	COSMIC	187.474	Down-regulation
Other_IKK_CHUK_ST	P35222	CTNNB1	O15111	CHUK	S33	G38X	38	Missense	distal	5	no	216.077	217.324	EPSD;PhosphoSitePlus	COSMIC	187.474	Up-regulation
Other_IKK_CHUK_ST	P35222	CTNNB1	O15111	CHUK	S33	D32X	32	Missense	proximal	-1	no	216.077	213.368	EPSD;PhosphoSitePlus	COSMIC	187.474	Down-regulation
Other_IKK_CHUK_ST	P35222	CTNNB1	O15111	CHUK	S33	S33K	33	Missense	central	0	yes	216.077	0.000	EPSD;PhosphoSitePlus	COSMIC	187.474	Loss
Other_IKK_CHUK_ST	P35222	CTNNB1	O15111	CHUK	S33	I35V	35	Missense	proximal	2	no	216.077	215.770	EPSD;PhosphoSitePlus	COSMIC	187.474	Down-regulation
Other_IKK_CHUK_ST	P35222	CTNNB1	O15111	CHUK	S33	S29T	29	Missense	distal	-4	no	216.077	198.707	EPSD;PhosphoSitePlus	COSMIC	187.474	Down-regulation
Other_IKK_CHUK_ST	P35222	CTNNB1	O15111	CHUK	S33	G34C	34	Missense	proximal	1	no	216.077	219.071	EPSD;PhosphoSitePlus	COSMIC	187.474	Up-regulation
Other_IKK_CHUK_ST	P35222	CTNNB1	O15111	CHUK	S33	G38S	38	Missense	distal	5	no	216.077	214.701	EPSD;PhosphoSitePlus	COSMIC	187.474	Down-regulation
Other_IKK_CHUK_ST	P35222	CTNNB1	O15111	CHUK	S33	S37V	37	Missense	distal	4	no	216.077	214.799	EPSD;PhosphoSitePlus	COSMIC	187.474	Down-regulation
Other_IKK_CHUK_ST	P35222	CTNNB1	O15111	CHUK	S33	I35F	35	Missense	proximal	2	no	216.077	214.563	EPSD;PhosphoSitePlus	COSMIC	187.474	Down-regulation
Other_IKK_CHUK_ST	P35222	CTNNB1	O15111	CHUK	S33	T40P	40	Missense	distal	7	no	216.077	214.867	EPSD;PhosphoSitePlus	COSMIC	187.474	Down-regulation
Other_IKK_CHUK_ST	P35222	CTNNB1	O15111	CHUK	S37	P44S	44	Missense	distal	7	no	235.061	228.396	PhosphoSitePlus;EPSD	COSMIC	187.474	Down-regulation
Other_IKK_CHUK_ST	P35222	CTNNB1	O15111	CHUK	S37	A43V	43	Missense	distal	6	no	235.061	242.574	PhosphoSitePlus;EPSD	COSMIC	187.474	Up-regulation
Other_IKK_CHUK_ST	P35222	CTNNB1	O15111	CHUK	S37	A39G	39	Missense	proximal	2	no	235.061	239.105	PhosphoSitePlus;EPSD	COSMIC	187.474	Up-regulation
Other_IKK_CHUK_ST	P35222	CTNNB1	O15111	CHUK	S37	G38A	38	Missense	proximal	1	no	235.061	232.958	PhosphoSitePlus;EPSD	COSMIC	187.474	Down-regulation
Other_IKK_CHUK_ST	P35222	CTNNB1	O15111	CHUK	S37	T40I	40	Missense	distal	3	no	235.061	200.200	PhosphoSitePlus;EPSD	COSMIC	187.474	Down-regulation
Other_IKK_CHUK_ST	P35222	CTNNB1	O15111	CHUK	S37	P44A	44	Missense	distal	7	no	235.061	232.659	PhosphoSitePlus;EPSD	COSMIC	187.474	Down-regulation
Other_IKK_CHUK_ST	P35222	CTNNB1	O15111	CHUK	S37	I35T	35	Missense	proximal	-2	no	235.061	230.004	PhosphoSitePlus;EPSD	COSMIC	187.474	Down-regulation
Other_IKK_CHUK_ST	P35222	CTNNB1	O15111	CHUK	S37	T41P	41	Missense	distal	4	no	235.061	236.353	PhosphoSitePlus;EPSD	COSMIC	187.474	Up-regulation
Other_IKK_CHUK_ST	P35222	CTNNB1	O15111	CHUK	S37	T42R	42	Missense	distal	5	no	235.061	236.982	PhosphoSitePlus;EPSD	COSMIC	187.474	Up-regulation
Other_IKK_CHUK_ST	P35222	CTNNB1	O15111	CHUK	S37	D32E	32	Missense	distal	-5	no	235.061	209.859	PhosphoSitePlus;EPSD	COSMIC	187.474	Down-regulation
Other_IKK_CHUK_ST	P35222	CTNNB1	O15111	CHUK	S37	H36R	36	Missense	proximal	-1	no	235.061	233.814	PhosphoSitePlus;EPSD	COSMIC	187.474	Down-regulation
Other_IKK_CHUK_ST	P35222	CTNNB1	O15111	CHUK	S37	T40A	40	Missense	distal	3	no	235.061	200.865	PhosphoSitePlus;EPSD	COSMIC	187.474	Down-regulation
Other_IKK_CHUK_ST	P35222	CTNNB1	O15111	CHUK	S37	A43T	43	Missense	distal	6	no	235.061	230.341	PhosphoSitePlus;EPSD	COSMIC	187.474	Down-regulation
Other_IKK_CHUK_ST	P35222	CTNNB1	O15111	CHUK	S37	P44L	44	Missense	distal	7	no	235.061	229.532	PhosphoSitePlus;EPSD	COSMIC	187.474	Down-regulation
Other_IKK_CHUK_ST	P35222	CTNNB1	O15111	CHUK	S37	G34L	34	Missense	distal	-3	no	235.061	224.816	PhosphoSitePlus;EPSD	COSMIC	187.474	Down-regulation
Other_IKK_CHUK_ST	P35222	CTNNB1	O15111	CHUK	S37	T42I	42	Missense	distal	5	no	235.061	231.123	PhosphoSitePlus;EPSD	COSMIC	187.474	Down-regulation
Other_IKK_CHUK_ST	P35222	CTNNB1	O15111	CHUK	S37	S33L	33	Missense	distal	-4	no	235.061	199.210	PhosphoSitePlus;EPSD	COSMIC;CCLE	187.474	Down-regulation
Other_IKK_CHUK_ST	P35222	CTNNB1	O15111	CHUK	S37	T42S	42	Missense	distal	5	no	235.061	233.200	PhosphoSitePlus;EPSD	COSMIC	187.474	Down-regulation
Other_IKK_CHUK_ST	P35222	CTNNB1	O15111	CHUK	S37	T42K	42	Missense	distal	5	no	235.061	237.298	PhosphoSitePlus;EPSD	COSMIC	187.474	Up-regulation
Other_IKK_CHUK_ST	P35222	CTNNB1	O15111	CHUK	S37	L31P	31	Missense	distal	-6	no	235.061	242.969	PhosphoSitePlus;EPSD	COSMIC	187.474	Up-regulation
Other_IKK_CHUK_ST	P35222	CTNNB1	O15111	CHUK	S37	S37L	37	Missense	central	0	yes	235.061	0.000	PhosphoSitePlus;EPSD	COSMIC	187.474	Loss
Other_IKK_CHUK_ST	P35222	CTNNB1	O15111	CHUK	S37	A39T	39	Missense	proximal	2	no	235.061	234.671	PhosphoSitePlus;EPSD	COSMIC	187.474	Down-regulation
Other_IKK_CHUK_ST	P35222	CTNNB1	O15111	CHUK	S37	S33N	33	Missense	distal	-4	no	235.061	238.172	PhosphoSitePlus;EPSD	COSMIC	187.474	Up-regulation
Other_IKK_CHUK_ST	P35222	CTNNB1	O15111	CHUK	S37	H36Y	36	Missense	proximal	-1	no	235.061	234.698	PhosphoSitePlus;EPSD	COSMIC	187.474	Down-regulation
Other_IKK_CHUK_ST	P35222	CTNNB1	O15111	CHUK	S37	A43P	43	Missense	distal	6	no	235.061	244.423	PhosphoSitePlus;EPSD	COSMIC	187.474	Up-regulation
Other_IKK_CHUK_ST	P35222	CTNNB1	O15111	CHUK	S37	Y30C	30	Missense	distal	-7	no	235.061	233.047	PhosphoSitePlus;EPSD	COSMIC	187.474	Down-regulation
Other_IKK_CHUK_ST	P35222	CTNNB1	O15111	CHUK	S37	G38P	38	Missense	proximal	1	no	235.061	240.415	PhosphoSitePlus;EPSD	COSMIC	187.474	Up-regulation
Other_IKK_CHUK_ST	P35222	CTNNB1	O15111	CHUK	S37	G38D	38	Missense	proximal	1	no	235.061	243.142	PhosphoSitePlus;EPSD	COSMIC	187.474	Up-regulation
Other_IKK_CHUK_ST	P35222	CTNNB1	O15111	CHUK	S37	T42A	42	Missense	distal	5	no	235.061	233.803	PhosphoSitePlus;EPSD	COSMIC	187.474	Down-regulation
Other_IKK_CHUK_ST	P35222	CTNNB1	O15111	CHUK	S37	I35M	35	Missense	proximal	-2	no	235.061	225.307	PhosphoSitePlus;EPSD	COSMIC	187.474	Down-regulation
Other_IKK_CHUK_ST	P35222	CTNNB1	O15111	CHUK	S37	T40S	40	Missense	distal	3	no	235.061	238.918	PhosphoSitePlus;EPSD	COSMIC	187.474	Up-regulation
Other_IKK_CHUK_ST	P35222	CTNNB1	O15111	CHUK	S37	G34A	34	Missense	distal	-3	no	235.061	228.312	PhosphoSitePlus;EPSD	COSMIC	187.474	Down-regulation
Other_IKK_CHUK_ST	P35222	CTNNB1	O15111	CHUK	S37	L31W	31	Missense	distal	-6	no	235.061	241.539	PhosphoSitePlus;EPSD	COSMIC	187.474	Up-regulation
Other_IKK_CHUK_ST	P35222	CTNNB1	O15111	CHUK	S37	T41S	41	Missense	distal	4	no	235.061	238.282	PhosphoSitePlus;EPSD	COSMIC	187.474	Up-regulation
Other_IKK_CHUK_ST	P35222	CTNNB1	O15111	CHUK	S37	G34I	34	Missense	distal	-3	no	235.061	228.213	PhosphoSitePlus;EPSD	COSMIC	187.474	Down-regulation
Other_IKK_CHUK_ST	P35222	CTNNB1	O15111	CHUK	S37	I35N	35	Missense	proximal	-2	no	235.061	218.554	PhosphoSitePlus;EPSD	COSMIC	187.474	Down-regulation
Other_IKK_CHUK_ST	P35222	CTNNB1	O15111	CHUK	S37	T42Q	42	Missense	distal	5	no	235.061	233.332	PhosphoSitePlus;EPSD	COSMIC	187.474	Down-regulation
Other_IKK_CHUK_ST	P35222	CTNNB1	O15111	CHUK	S37	D32C	32	Missense	distal	-5	no	235.061	209.625	PhosphoSitePlus;EPSD	COSMIC	187.474	Down-regulation
Other_IKK_CHUK_ST	P35222	CTNNB1	O15111	CHUK	S37	Y30S	30	Missense	distal	-7	no	235.061	238.621	PhosphoSitePlus;EPSD	COSMIC	187.474	Up-regulation
Other_IKK_CHUK_ST	P35222	CTNNB1	O15111	CHUK	S37	L31M	31	Missense	distal	-6	no	235.061	240.329	PhosphoSitePlus;EPSD	COSMIC	187.474	Up-regulation
Other_IKK_CHUK_ST	P35222	CTNNB1	O15111	CHUK	S37	A39V	39	Missense	proximal	2	no	235.061	235.577	PhosphoSitePlus;EPSD	COSMIC	187.474	Up-regulation
Other_IKK_CHUK_ST	P35222	CTNNB1	O15111	CHUK	S37	L31Q	31	Missense	distal	-6	no	235.061	237.681	PhosphoSitePlus;EPSD	COSMIC	187.474	Up-regulation
Other_IKK_CHUK_ST	P35222	CTNNB1	O15111	CHUK	S37	G34D	34	Missense	distal	-3	no	235.061	226.011	PhosphoSitePlus;EPSD	COSMIC	187.474	Down-regulation
Other_IKK_CHUK_ST	P35222	CTNNB1	O15111	CHUK	S37	I35K	35	Missense	proximal	-2	no	235.061	229.198	PhosphoSitePlus;EPSD	COSMIC	187.474	Down-regulation
Other_IKK_CHUK_ST	P35222	CTNNB1	O15111	CHUK	S37	D32F	32	Missense	distal	-5	no	235.061	207.665	PhosphoSitePlus;EPSD	COSMIC	187.474	Down-regulation
Other_IKK_CHUK_ST	P35222	CTNNB1	O15111	CHUK	S37	G38X	38	Missense	proximal	1	no	235.061	240.897	PhosphoSitePlus;EPSD	COSMIC	187.474	Up-regulation
Other_IKK_CHUK_ST	P35222	CTNNB1	O15111	CHUK	S37	D32X	32	Missense	distal	-5	no	235.061	215.854	PhosphoSitePlus;EPSD	COSMIC	187.474	Down-regulation
Other_IKK_CHUK_ST	P35222	CTNNB1	O15111	CHUK	S37	S33K	33	Missense	distal	-4	no	235.061	226.821	PhosphoSitePlus;EPSD	COSMIC	187.474	Down-regulation
Other_IKK_CHUK_ST	P35222	CTNNB1	O15111	CHUK	S37	I35V	35	Missense	proximal	-2	no	235.061	234.354	PhosphoSitePlus;EPSD	COSMIC	187.474	Down-regulation
Other_IKK_CHUK_ST	P35222	CTNNB1	O15111	CHUK	S37	G34C	34	Missense	distal	-3	no	235.061	229.955	PhosphoSitePlus;EPSD	COSMIC	187.474	Down-regulation
Other_IKK_CHUK_ST	P35222	CTNNB1	O15111	CHUK	S37	G38S	38	Missense	proximal	1	no	235.061	235.014	PhosphoSitePlus;EPSD	COSMIC	187.474	Down-regulation
Other_IKK_CHUK_ST	P35222	CTNNB1	O15111	CHUK	S37	S37V	37	Missense	central	0	yes	235.061	0.000	PhosphoSitePlus;EPSD	COSMIC	187.474	Loss
Other_IKK_CHUK_ST	P35222	CTNNB1	O15111	CHUK	S37	P44I	44	Missense	distal	7	no	235.061	229.784	PhosphoSitePlus;EPSD	COSMIC	187.474	Down-regulation
Other_IKK_CHUK_ST	P35222	CTNNB1	O15111	CHUK	S37	I35F	35	Missense	proximal	-2	no	235.061	239.237	PhosphoSitePlus;EPSD	COSMIC	187.474	Up-regulation
Other_IKK_CHUK_ST	P35222	CTNNB1	O15111	CHUK	S37	T40P	40	Missense	distal	3	no	235.061	240.494	PhosphoSitePlus;EPSD	COSMIC	187.474	Up-regulation
Other_IKK_CHUK_ST	P35222	CTNNB1	O15111	CHUK	T41	S45T	45	Missense	distal	4	no	218.452	215.230	EPSD;PhosphoSitePlus	COSMIC	187.474	Down-regulation
Other_IKK_CHUK_ST	P35222	CTNNB1	O15111	CHUK	T41	P44S	44	Missense	distal	3	no	218.452	216.877	EPSD;PhosphoSitePlus	COSMIC	187.474	Down-regulation
Other_IKK_CHUK_ST	P35222	CTNNB1	O15111	CHUK	T41	A43V	43	Missense	proximal	2	no	218.452	218.969	EPSD;PhosphoSitePlus	COSMIC	187.474	Up-regulation
Other_IKK_CHUK_ST	P35222	CTNNB1	O15111	CHUK	T41	G48D	48	Missense	distal	7	no	218.452	210.413	EPSD;PhosphoSitePlus	COSMIC	187.474	Down-regulation
Other_IKK_CHUK_ST	P35222	CTNNB1	O15111	CHUK	T41	A39G	39	Missense	proximal	-2	no	218.452	182.516	EPSD;PhosphoSitePlus	COSMIC	187.474	Loss
Other_IKK_CHUK_ST	P35222	CTNNB1	O15111	CHUK	T41	G38A	38	Missense	distal	-3	no	218.452	211.704	EPSD;PhosphoSitePlus	COSMIC	187.474	Down-regulation
Other_IKK_CHUK_ST	P35222	CTNNB1	O15111	CHUK	T41	T40I	40	Missense	proximal	-1	no	218.452	216.164	EPSD;PhosphoSitePlus	COSMIC	187.474	Down-regulation
Other_IKK_CHUK_ST	P35222	CTNNB1	O15111	CHUK	T41	P44A	44	Missense	distal	3	no	218.452	178.823	EPSD;PhosphoSitePlus	COSMIC	187.474	Loss
Other_IKK_CHUK_ST	P35222	CTNNB1	O15111	CHUK	T41	I35T	35	Missense	distal	-6	no	218.452	215.102	EPSD;PhosphoSitePlus	COSMIC	187.474	Down-regulation
Other_IKK_CHUK_ST	P35222	CTNNB1	O15111	CHUK	T41	T41P	41	Missense	central	0	yes	218.452	0.000	EPSD;PhosphoSitePlus	COSMIC	187.474	Loss
Other_IKK_CHUK_ST	P35222	CTNNB1	O15111	CHUK	T41	T42R	42	Missense	proximal	1	no	218.452	208.557	EPSD;PhosphoSitePlus	COSMIC	187.474	Down-regulation
Other_IKK_CHUK_ST	P35222	CTNNB1	O15111	CHUK	T41	S45A	45	Missense	distal	4	no	218.452	212.543	EPSD;PhosphoSitePlus	COSMIC	187.474	Down-regulation
Other_IKK_CHUK_ST	P35222	CTNNB1	O15111	CHUK	T41	H36R	36	Missense	distal	-5	no	218.452	213.567	EPSD;PhosphoSitePlus	COSMIC	187.474	Down-regulation
Other_IKK_CHUK_ST	P35222	CTNNB1	O15111	CHUK	T41	G48S	48	Missense	distal	7	no	218.452	205.880	EPSD;PhosphoSitePlus	COSMIC	187.474	Down-regulation
Other_IKK_CHUK_ST	P35222	CTNNB1	O15111	CHUK	T41	T40A	40	Missense	proximal	-1	no	218.452	216.339	EPSD;PhosphoSitePlus	COSMIC	187.474	Down-regulation
Other_IKK_CHUK_ST	P35222	CTNNB1	O15111	CHUK	T41	A43T	43	Missense	proximal	2	no	218.452	218.063	EPSD;PhosphoSitePlus	COSMIC	187.474	Down-regulation
Other_IKK_CHUK_ST	P35222	CTNNB1	O15111	CHUK	T41	P44L	44	Missense	distal	3	no	218.452	214.106	EPSD;PhosphoSitePlus	COSMIC	187.474	Down-regulation
Other_IKK_CHUK_ST	P35222	CTNNB1	O15111	CHUK	T41	G34L	34	Missense	distal	-7	no	218.452	216.518	EPSD;PhosphoSitePlus	COSMIC	187.474	Down-regulation
Other_IKK_CHUK_ST	P35222	CTNNB1	O15111	CHUK	T41	T42I	42	Missense	proximal	1	no	218.452	226.666	EPSD;PhosphoSitePlus	COSMIC	187.474	Up-regulation
Other_IKK_CHUK_ST	P35222	CTNNB1	O15111	CHUK	T41	T42S	42	Missense	proximal	1	no	218.452	214.833	EPSD;PhosphoSitePlus	COSMIC	187.474	Down-regulation
Other_IKK_CHUK_ST	P35222	CTNNB1	O15111	CHUK	T41	T42K	42	Missense	proximal	1	no	218.452	220.163	EPSD;PhosphoSitePlus	COSMIC	187.474	Up-regulation
Other_IKK_CHUK_ST	P35222	CTNNB1	O15111	CHUK	T41	S47G	47	Missense	distal	6	no	218.452	215.636	EPSD;PhosphoSitePlus	COSMIC	187.474	Down-regulation
Other_IKK_CHUK_ST	P35222	CTNNB1	O15111	CHUK	T41	G48V	48	Missense	distal	7	no	218.452	218.113	EPSD;PhosphoSitePlus	COSMIC	187.474	Down-regulation
Other_IKK_CHUK_ST	P35222	CTNNB1	O15111	CHUK	T41	S47N	47	Missense	distal	6	no	218.452	221.923	EPSD;PhosphoSitePlus	COSMIC	187.474	Up-regulation
Other_IKK_CHUK_ST	P35222	CTNNB1	O15111	CHUK	T41	S37L	37	Missense	distal	-4	no	218.452	182.601	EPSD;PhosphoSitePlus	COSMIC	187.474	Loss
Other_IKK_CHUK_ST	P35222	CTNNB1	O15111	CHUK	T41	A39T	39	Missense	proximal	-2	no	218.452	196.034	EPSD;PhosphoSitePlus	COSMIC	187.474	Down-regulation
Other_IKK_CHUK_ST	P35222	CTNNB1	O15111	CHUK	T41	H36Y	36	Missense	distal	-5	no	218.452	223.139	EPSD;PhosphoSitePlus	COSMIC	187.474	Up-regulation
Other_IKK_CHUK_ST	P35222	CTNNB1	O15111	CHUK	T41	A43P	43	Missense	proximal	2	no	218.452	221.836	EPSD;PhosphoSitePlus	COSMIC	187.474	Up-regulation
Other_IKK_CHUK_ST	P35222	CTNNB1	O15111	CHUK	T41	L46P	46	Missense	distal	5	no	218.452	221.226	EPSD;PhosphoSitePlus	COSMIC	187.474	Up-regulation
Other_IKK_CHUK_ST	P35222	CTNNB1	O15111	CHUK	T41	G38P	38	Missense	distal	-3	no	218.452	218.312	EPSD;PhosphoSitePlus	COSMIC	187.474	Down-regulation
Other_IKK_CHUK_ST	P35222	CTNNB1	O15111	CHUK	T41	G38D	38	Missense	distal	-3	no	218.452	209.402	EPSD;PhosphoSitePlus	COSMIC	187.474	Down-regulation
Other_IKK_CHUK_ST	P35222	CTNNB1	O15111	CHUK	T41	T42A	42	Missense	proximal	1	no	218.452	212.777	EPSD;PhosphoSitePlus	COSMIC	187.474	Down-regulation
Other_IKK_CHUK_ST	P35222	CTNNB1	O15111	CHUK	T41	L46V	46	Missense	distal	5	no	218.452	220.374	EPSD;PhosphoSitePlus	COSMIC	187.474	Up-regulation
Other_IKK_CHUK_ST	P35222	CTNNB1	O15111	CHUK	T41	S47L	47	Missense	distal	6	no	218.452	219.985	EPSD;PhosphoSitePlus	COSMIC	187.474	Up-regulation
Other_IKK_CHUK_ST	P35222	CTNNB1	O15111	CHUK	T41	I35M	35	Missense	distal	-6	no	218.452	219.606	EPSD;PhosphoSitePlus	COSMIC	187.474	Up-regulation
Other_IKK_CHUK_ST	P35222	CTNNB1	O15111	CHUK	T41	T40S	40	Missense	proximal	-1	no	218.452	217.987	EPSD;PhosphoSitePlus	COSMIC	187.474	Down-regulation
Other_IKK_CHUK_ST	P35222	CTNNB1	O15111	CHUK	T41	L46M	46	Missense	distal	5	no	218.452	221.381	EPSD;PhosphoSitePlus	COSMIC	187.474	Up-regulation
Other_IKK_CHUK_ST	P35222	CTNNB1	O15111	CHUK	T41	G34A	34	Missense	distal	-7	no	218.452	215.837	EPSD;PhosphoSitePlus	COSMIC	187.474	Down-regulation
Other_IKK_CHUK_ST	P35222	CTNNB1	O15111	CHUK	T41	S47T	47	Missense	distal	6	no	218.452	213.171	EPSD;PhosphoSitePlus	COSMIC	187.474	Down-regulation
Other_IKK_CHUK_ST	P35222	CTNNB1	O15111	CHUK	T41	G34I	34	Missense	distal	-7	no	218.452	216.832	EPSD;PhosphoSitePlus	COSMIC	187.474	Down-regulation
Other_IKK_CHUK_ST	P35222	CTNNB1	O15111	CHUK	T41	I35N	35	Missense	distal	-6	no	218.452	219.761	EPSD;PhosphoSitePlus	COSMIC	187.474	Up-regulation
Other_IKK_CHUK_ST	P35222	CTNNB1	O15111	CHUK	T41	T42Q	42	Missense	proximal	1	no	218.452	217.575	EPSD;PhosphoSitePlus	COSMIC	187.474	Down-regulation
Other_IKK_CHUK_ST	P35222	CTNNB1	O15111	CHUK	T41	S47C	47	Missense	distal	6	no	218.452	223.913	EPSD;PhosphoSitePlus	COSMIC	187.474	Up-regulation
Other_IKK_CHUK_ST	P35222	CTNNB1	O15111	CHUK	T41	S47R	47	Missense	distal	6	no	218.452	221.589	EPSD;PhosphoSitePlus	COSMIC	187.474	Up-regulation
Other_IKK_CHUK_ST	P35222	CTNNB1	O15111	CHUK	T41	A39V	39	Missense	proximal	-2	no	218.452	200.383	EPSD;PhosphoSitePlus	COSMIC	187.474	Down-regulation
Other_IKK_CHUK_ST	P35222	CTNNB1	O15111	CHUK	T41	S45E	45	Missense	distal	4	no	218.452	213.038	EPSD;PhosphoSitePlus	COSMIC	187.474	Down-regulation
Other_IKK_CHUK_ST	P35222	CTNNB1	O15111	CHUK	T41	G34D	34	Missense	distal	-7	no	218.452	219.075	EPSD;PhosphoSitePlus	COSMIC	187.474	Up-regulation
Other_IKK_CHUK_ST	P35222	CTNNB1	O15111	CHUK	T41	S37T	37	Missense	distal	-4	no	218.452	201.082	EPSD;PhosphoSitePlus	COSMIC	187.474	Down-regulation
Other_IKK_CHUK_ST	P35222	CTNNB1	O15111	CHUK	T41	I35K	35	Missense	distal	-6	no	218.452	220.855	EPSD;PhosphoSitePlus	COSMIC	187.474	Up-regulation
Other_IKK_CHUK_ST	P35222	CTNNB1	O15111	CHUK	T41	S45N	45	Missense	distal	4	no	218.452	217.039	EPSD;PhosphoSitePlus	COSMIC	187.474	Down-regulation
Other_IKK_CHUK_ST	P35222	CTNNB1	O15111	CHUK	T41	G38X	38	Missense	distal	-3	no	218.452	210.778	EPSD;PhosphoSitePlus	COSMIC	187.474	Down-regulation
Other_IKK_CHUK_ST	P35222	CTNNB1	O15111	CHUK	T41	L46Q	46	Missense	distal	5	no	218.452	215.997	EPSD;PhosphoSitePlus	COSMIC	187.474	Down-regulation
Other_IKK_CHUK_ST	P35222	CTNNB1	O15111	CHUK	T41	I35V	35	Missense	distal	-6	no	218.452	217.453	EPSD;PhosphoSitePlus	COSMIC	187.474	Down-regulation
Other_IKK_CHUK_ST	P35222	CTNNB1	O15111	CHUK	T41	S45X	45	Missense	distal	4	no	218.452	214.999	EPSD;PhosphoSitePlus	COSMIC	187.474	Down-regulation
Other_IKK_CHUK_ST	P35222	CTNNB1	O15111	CHUK	T41	G34C	34	Missense	distal	-7	no	218.452	213.916	EPSD;PhosphoSitePlus	COSMIC	187.474	Down-regulation
Other_IKK_CHUK_ST	P35222	CTNNB1	O15111	CHUK	T41	G38S	38	Missense	distal	-3	no	218.452	204.444	EPSD;PhosphoSitePlus	COSMIC	187.474	Down-regulation
Other_IKK_CHUK_ST	P35222	CTNNB1	O15111	CHUK	T41	S37V	37	Missense	distal	-4	no	218.452	197.440	EPSD;PhosphoSitePlus	COSMIC	187.474	Down-regulation
Other_IKK_CHUK_ST	P35222	CTNNB1	O15111	CHUK	T41	P44I	44	Missense	distal	3	no	218.452	178.159	EPSD;PhosphoSitePlus	COSMIC	187.474	Loss
Other_IKK_CHUK_ST	P35222	CTNNB1	O15111	CHUK	T41	I35F	35	Missense	distal	-6	no	218.452	219.852	EPSD;PhosphoSitePlus	COSMIC	187.474	Up-regulation
Other_IKK_CHUK_ST	P35222	CTNNB1	O15111	CHUK	T41	S47I	47	Missense	distal	6	no	218.452	219.709	EPSD;PhosphoSitePlus	COSMIC	187.474	Up-regulation
Other_IKK_CHUK_ST	P35222	CTNNB1	O15111	CHUK	T41	S47Y	47	Missense	distal	6	no	218.452	217.671	EPSD;PhosphoSitePlus	COSMIC	187.474	Down-regulation
Other_IKK_CHUK_ST	P35222	CTNNB1	O15111	CHUK	T41	T40P	40	Missense	proximal	-1	no	218.452	216.926	EPSD;PhosphoSitePlus	COSMIC	187.474	Down-regulation
Other_IKK_CHUK_ST	P35222	CTNNB1	O15111	CHUK	S45	P44S	44	Missense	proximal	-1	no	247.229	248.290	EPSD;PhosphoSitePlus	COSMIC	187.474	Up-regulation
Other_IKK_CHUK_ST	P35222	CTNNB1	O15111	CHUK	S45	A43V	43	Missense	proximal	-2	no	247.229	229.160	EPSD;PhosphoSitePlus	COSMIC	187.474	Down-regulation
Other_IKK_CHUK_ST	P35222	CTNNB1	O15111	CHUK	S45	G48D	48	Missense	distal	3	no	247.229	274.969	EPSD;PhosphoSitePlus	COSMIC	187.474	Up-regulation
Other_IKK_CHUK_ST	P35222	CTNNB1	O15111	CHUK	S45	A39G	39	Missense	distal	-6	no	247.229	245.951	EPSD;PhosphoSitePlus	COSMIC	187.474	Down-regulation
Other_IKK_CHUK_ST	P35222	CTNNB1	O15111	CHUK	S45	N51T	51	Missense	distal	6	no	247.229	238.477	EPSD;PhosphoSitePlus	COSMIC	187.474	Down-regulation
Other_IKK_CHUK_ST	P35222	CTNNB1	O15111	CHUK	S45	P52L	52	Missense	distal	7	no	247.229	241.701	EPSD;PhosphoSitePlus	COSMIC	187.474	Down-regulation
Other_IKK_CHUK_ST	P35222	CTNNB1	O15111	CHUK	S45	N51S	51	Missense	distal	6	no	247.229	243.759	EPSD;PhosphoSitePlus	COSMIC	187.474	Down-regulation
Other_IKK_CHUK_ST	P35222	CTNNB1	O15111	CHUK	S45	G38A	38	Missense	distal	-7	no	247.229	244.614	EPSD;PhosphoSitePlus	COSMIC	187.474	Down-regulation
Other_IKK_CHUK_ST	P35222	CTNNB1	O15111	CHUK	S45	T40I	40	Missense	distal	-5	no	247.229	232.165	EPSD;PhosphoSitePlus	COSMIC	187.474	Down-regulation
Other_IKK_CHUK_ST	P35222	CTNNB1	O15111	CHUK	S45	P44A	44	Missense	proximal	-1	no	247.229	246.643	EPSD;PhosphoSitePlus	COSMIC	187.474	Down-regulation
Other_IKK_CHUK_ST	P35222	CTNNB1	O15111	CHUK	S45	T41P	41	Missense	distal	-4	no	247.229	256.982	EPSD;PhosphoSitePlus	COSMIC	187.474	Up-regulation
Other_IKK_CHUK_ST	P35222	CTNNB1	O15111	CHUK	S45	K49R	49	Missense	distal	4	no	247.229	245.792	EPSD;PhosphoSitePlus	COSMIC	187.474	Down-regulation
Other_IKK_CHUK_ST	P35222	CTNNB1	O15111	CHUK	S45	T42R	42	Missense	distal	-3	no	247.229	258.665	EPSD;PhosphoSitePlus	COSMIC	187.474	Up-regulation
Other_IKK_CHUK_ST	P35222	CTNNB1	O15111	CHUK	S45	S45A	45	Missense	central	0	yes	247.229	0.000	EPSD;PhosphoSitePlus	COSMIC	187.474	Loss
Other_IKK_CHUK_ST	P35222	CTNNB1	O15111	CHUK	S45	G48S	48	Missense	distal	3	no	247.229	235.310	EPSD;PhosphoSitePlus	COSMIC	187.474	Down-regulation
Other_IKK_CHUK_ST	P35222	CTNNB1	O15111	CHUK	S45	T40A	40	Missense	distal	-5	no	247.229	237.650	EPSD;PhosphoSitePlus	COSMIC	187.474	Down-regulation
Other_IKK_CHUK_ST	P35222	CTNNB1	O15111	CHUK	S45	A43T	43	Missense	proximal	-2	no	247.229	224.811	EPSD;PhosphoSitePlus	COSMIC	187.474	Down-regulation
Other_IKK_CHUK_ST	P35222	CTNNB1	O15111	CHUK	S45	P44L	44	Missense	proximal	-1	no	247.229	249.221	EPSD;PhosphoSitePlus	COSMIC	187.474	Up-regulation
Other_IKK_CHUK_ST	P35222	CTNNB1	O15111	CHUK	S45	T42I	42	Missense	distal	-3	no	247.229	246.848	EPSD;PhosphoSitePlus	COSMIC	187.474	Down-regulation
Other_IKK_CHUK_ST	P35222	CTNNB1	O15111	CHUK	S45	T42S	42	Missense	distal	-3	no	247.229	239.687	EPSD;PhosphoSitePlus	COSMIC	187.474	Down-regulation
Other_IKK_CHUK_ST	P35222	CTNNB1	O15111	CHUK	S45	T42K	42	Missense	distal	-3	no	247.229	251.284	EPSD;PhosphoSitePlus	COSMIC	187.474	Up-regulation
Other_IKK_CHUK_ST	P35222	CTNNB1	O15111	CHUK	S45	S47G	47	Missense	proximal	2	no	247.229	251.718	EPSD;PhosphoSitePlus	COSMIC	187.474	Up-regulation
Other_IKK_CHUK_ST	P35222	CTNNB1	O15111	CHUK	S45	G48V	48	Missense	distal	3	no	247.229	196.639	EPSD;PhosphoSitePlus	COSMIC	187.474	Down-regulation
Other_IKK_CHUK_ST	P35222	CTNNB1	O15111	CHUK	S45	S47N	47	Missense	proximal	2	no	247.229	250.187	EPSD;PhosphoSitePlus	COSMIC	187.474	Up-regulation
Other_IKK_CHUK_ST	P35222	CTNNB1	O15111	CHUK	S45	A39T	39	Missense	distal	-6	no	247.229	243.361	EPSD;PhosphoSitePlus	COSMIC	187.474	Down-regulation
Other_IKK_CHUK_ST	P35222	CTNNB1	O15111	CHUK	S45	K49T	49	Missense	distal	4	no	247.229	244.098	EPSD;PhosphoSitePlus	COSMIC	187.474	Down-regulation
Other_IKK_CHUK_ST	P35222	CTNNB1	O15111	CHUK	S45	G50D	50	Missense	distal	5	no	247.229	247.900	EPSD;PhosphoSitePlus	COSMIC	187.474	Up-regulation
Other_IKK_CHUK_ST	P35222	CTNNB1	O15111	CHUK	S45	A43P	43	Missense	proximal	-2	no	247.229	196.768	EPSD;PhosphoSitePlus	COSMIC	187.474	Down-regulation
Other_IKK_CHUK_ST	P35222	CTNNB1	O15111	CHUK	S45	L46P	46	Missense	proximal	1	no	247.229	233.156	EPSD;PhosphoSitePlus	COSMIC	187.474	Down-regulation
Other_IKK_CHUK_ST	P35222	CTNNB1	O15111	CHUK	S45	G38P	38	Missense	distal	-7	no	247.229	244.733	EPSD;PhosphoSitePlus	COSMIC	187.474	Down-regulation
Other_IKK_CHUK_ST	P35222	CTNNB1	O15111	CHUK	S45	G38D	38	Missense	distal	-7	no	247.229	247.852	EPSD;PhosphoSitePlus	COSMIC	187.474	Up-regulation
Other_IKK_CHUK_ST	P35222	CTNNB1	O15111	CHUK	S45	T42A	42	Missense	distal	-3	no	247.229	246.947	EPSD;PhosphoSitePlus	COSMIC	187.474	Down-regulation
Other_IKK_CHUK_ST	P35222	CTNNB1	O15111	CHUK	S45	L46V	46	Missense	proximal	1	no	247.229	240.929	EPSD;PhosphoSitePlus	COSMIC	187.474	Down-regulation
Other_IKK_CHUK_ST	P35222	CTNNB1	O15111	CHUK	S45	S47L	47	Missense	proximal	2	no	247.229	246.897	EPSD;PhosphoSitePlus	COSMIC	187.474	Down-regulation
Other_IKK_CHUK_ST	P35222	CTNNB1	O15111	CHUK	S45	T40S	40	Missense	distal	-5	no	247.229	252.911	EPSD;PhosphoSitePlus	COSMIC	187.474	Up-regulation
Other_IKK_CHUK_ST	P35222	CTNNB1	O15111	CHUK	S45	K49L	49	Missense	distal	4	no	247.229	246.180	EPSD;PhosphoSitePlus	COSMIC	187.474	Down-regulation
Other_IKK_CHUK_ST	P35222	CTNNB1	O15111	CHUK	S45	L46M	46	Missense	proximal	1	no	247.229	242.030	EPSD;PhosphoSitePlus	COSMIC	187.474	Down-regulation
Other_IKK_CHUK_ST	P35222	CTNNB1	O15111	CHUK	S45	S47T	47	Missense	proximal	2	no	247.229	247.284	EPSD;PhosphoSitePlus	COSMIC	187.474	Up-regulation
Other_IKK_CHUK_ST	P35222	CTNNB1	O15111	CHUK	S45	T41S	41	Missense	distal	-4	no	247.229	264.599	EPSD;PhosphoSitePlus	COSMIC	187.474	Up-regulation
Other_IKK_CHUK_ST	P35222	CTNNB1	O15111	CHUK	S45	T42Q	42	Missense	distal	-3	no	247.229	232.735	EPSD;PhosphoSitePlus	COSMIC	187.474	Down-regulation
Other_IKK_CHUK_ST	P35222	CTNNB1	O15111	CHUK	S45	S47C	47	Missense	proximal	2	no	247.229	251.274	EPSD;PhosphoSitePlus	COSMIC	187.474	Up-regulation
Other_IKK_CHUK_ST	P35222	CTNNB1	O15111	CHUK	S45	K49E	49	Missense	distal	4	no	247.229	241.905	EPSD;PhosphoSitePlus	COSMIC	187.474	Down-regulation
Other_IKK_CHUK_ST	P35222	CTNNB1	O15111	CHUK	S45	S47R	47	Missense	proximal	2	no	247.229	248.591	EPSD;PhosphoSitePlus	COSMIC	187.474	Up-regulation
Other_IKK_CHUK_ST	P35222	CTNNB1	O15111	CHUK	S45	A39V	39	Missense	distal	-6	no	247.229	245.712	EPSD;PhosphoSitePlus	COSMIC	187.474	Down-regulation
Other_IKK_CHUK_ST	P35222	CTNNB1	O15111	CHUK	S45	S45E	45	Missense	central	0	yes	247.229	0.000	EPSD;PhosphoSitePlus	COSMIC	187.474	Loss
Other_IKK_CHUK_ST	P35222	CTNNB1	O15111	CHUK	S45	G50S	50	Missense	distal	5	no	247.229	245.854	EPSD;PhosphoSitePlus	COSMIC	187.474	Down-regulation
Other_IKK_CHUK_ST	P35222	CTNNB1	O15111	CHUK	S45	S45N	45	Missense	central	0	yes	247.229	0.000	EPSD;PhosphoSitePlus	COSMIC	187.474	Loss
Other_IKK_CHUK_ST	P35222	CTNNB1	O15111	CHUK	S45	G38X	38	Missense	distal	-7	no	247.229	245.915	EPSD;PhosphoSitePlus	COSMIC	187.474	Down-regulation
Other_IKK_CHUK_ST	P35222	CTNNB1	O15111	CHUK	S45	L46Q	46	Missense	proximal	1	no	247.229	230.498	EPSD;PhosphoSitePlus	COSMIC	187.474	Down-regulation
Other_IKK_CHUK_ST	P35222	CTNNB1	O15111	CHUK	S45	S45X	45	Missense	central	0	yes	247.229	0.000	EPSD;PhosphoSitePlus	COSMIC	187.474	Loss
Other_IKK_CHUK_ST	P35222	CTNNB1	O15111	CHUK	S45	G38S	38	Missense	distal	-7	no	247.229	248.267	EPSD;PhosphoSitePlus	COSMIC	187.474	Up-regulation
Other_IKK_CHUK_ST	P35222	CTNNB1	O15111	CHUK	S45	P44I	44	Missense	proximal	-1	no	247.229	246.468	EPSD;PhosphoSitePlus	COSMIC	187.474	Down-regulation
Other_IKK_CHUK_ST	P35222	CTNNB1	O15111	CHUK	S45	S47I	47	Missense	proximal	2	no	247.229	248.497	EPSD;PhosphoSitePlus	COSMIC	187.474	Up-regulation
Other_IKK_CHUK_ST	P35222	CTNNB1	O15111	CHUK	S45	S47Y	47	Missense	proximal	2	no	247.229	250.518	EPSD;PhosphoSitePlus	COSMIC	187.474	Up-regulation
Other_IKK_CHUK_ST	P35222	CTNNB1	O15111	CHUK	S45	T40P	40	Missense	distal	-5	no	247.229	244.257	EPSD;PhosphoSitePlus	COSMIC	187.474	Down-regulation
Other_IKK_CHUK_ST	P35222	CTNNB1	O15111	CHUK	S47	S45A	45	Missense	proximal	-2	no	176.444	202.100	EPSD	COSMIC	187.474	Gain
Other_IKK_CHUK_ST	P35222	CTNNB1	O15111	CHUK	S47	G48V	48	Missense	proximal	1	no	176.444	189.571	EPSD	COSMIC	187.474	Gain
Other_IKK_CHUK_ST	P35222	CTNNB1	O15111	CHUK	S47	G50D	50	Missense	distal	3	no	176.444	204.183	EPSD	COSMIC	187.474	Gain
Other_IKK_CHUK_ST	P35222	CTNNB1	O15111	CHUK	S179	H176R	176	Missense	distal	-3	no	210.016	222.706	EPSD	COSMIC	187.474	Up-regulation
Other_IKK_CHUK_ST	P35222	CTNNB1	O15111	CHUK	S179	A183S	183	Missense	distal	4	no	210.016	215.925	EPSD	COSMIC	187.474	Up-regulation
Other_IKK_CHUK_ST	P35222	CTNNB1	O15111	CHUK	S179	Q177P	177	Missense	proximal	-2	no	210.016	165.764	EPSD	COSMIC	187.474	Loss
Other_IKK_CHUK_ST	P35222	CTNNB1	O15111	CHUK	S179	V175I	175	Missense	distal	-4	no	210.016	212.592	EPSD	COSMIC	187.474	Up-regulation
Other_IKK_CHUK_ST	P35222	CTNNB1	O15111	CHUK	S179	A183T	183	Missense	distal	4	no	210.016	212.703	EPSD	COSMIC	187.474	Up-regulation
Other_IKK_CHUK_ST	P35222	CTNNB1	O15111	CHUK	S179	E182D	182	Missense	distal	3	no	210.016	255.783	EPSD	COSMIC	187.474	Up-regulation
Other_IKK_CHUK_ST	P35222	CTNNB1	O15111	CHUK	S179	R185K	185	Missense	distal	6	no	210.016	210.967	EPSD	COSMIC	187.474	Up-regulation
Other_IKK_CHUK_ST	P35222	CTNNB1	O15111	CHUK	S184	A187D	187	Missense	distal	3	no	128.980	206.691	EPSD	COSMIC	187.474	Gain
Other_IKK_CHUK_ST	P35222	CTNNB1	O15111	CHUK	S246	M243T	243	Missense	distal	-3	no	216.740	227.918	EPSD	COSMIC	187.474	Up-regulation
Other_IKK_CHUK_ST	P35222	CTNNB1	O15111	CHUK	S246	S246L	246	Missense	central	0	yes	216.740	0.000	EPSD	COSMIC	187.474	Loss
Other_IKK_CHUK_ST	P35222	CTNNB1	O15111	CHUK	S246	G245A	245	Missense	proximal	-1	no	216.740	216.668	EPSD	COSMIC;GDSC	187.474	Down-regulation
Other_IKK_CHUK_ST	P35222	CTNNB1	O15111	CHUK	S246	G245D	245	Missense	proximal	-1	no	216.740	220.491	EPSD	COSMIC	187.474	Up-regulation
Other_IKK_CHUK_ST	P35222	CTNNB1	O15111	CHUK	S246	A239V	239	Missense	distal	-7	no	216.740	216.216	EPSD	COSMIC	187.474	Down-regulation
Other_IKK_CHUK_ST	P35222	CTNNB1	O15111	CHUK	S246	K242E	242	Missense	distal	-4	no	216.740	204.975	EPSD	COSMIC	187.474	Down-regulation
Other_IKK_CHUK_ST	P35222	CTNNB1	O15111	CHUK	S246	A239G	239	Missense	distal	-7	no	216.740	219.355	EPSD	COSMIC	187.474	Up-regulation
Other_IKK_CHUK_ST	P35222	CTNNB1	O15111	CHUK	S715	Y716C	716	Missense	proximal	1	no	200.492	204.227	EPSD	COSMIC	187.474	Up-regulation
Other_IKK_CHUK_ST	P35222	CTNNB1	O15111	CHUK	S715	H720P	720	Missense	distal	5	no	200.492	200.276	EPSD	COSMIC	187.474	Down-regulation
Other_IKK_CHUK_ST	P35222	CTNNB1	O15111	CHUK	S715	R717C	717	Missense	proximal	2	no	200.492	203.176	EPSD	COSMIC	187.474	Up-regulation
Other_IKK_CHUK_ST	P35222	CTNNB1	O15111	CHUK	S715	S715R	715	Missense	central	0	yes	200.492	0.000	EPSD	COSMIC	187.474	Loss
Other_IKK_CHUK_ST	P35222	CTNNB1	O15111	CHUK	S715	D712N	712	Missense	distal	-3	no	200.492	198.843	EPSD	COSMIC	187.474	Down-regulation
Other_IKK_CHUK_ST	P35222	CTNNB1	O15111	CHUK	S715	P714S	714	Missense	proximal	-1	no	200.492	201.553	EPSD	COSMIC	187.474	Up-regulation
Other_IKK_CHUK_ST	P35222	CTNNB1	O15111	CHUK	S715	Y709C	709	Missense	distal	-6	no	200.492	203.949	EPSD	COSMIC	187.474	Up-regulation
Other_IKK_CHUK_ST	P35222	CTNNB1	O15111	CHUK	S715	R710C	710	Missense	distal	-5	no	200.492	199.644	EPSD	COSMIC	187.474	Down-regulation
Other_IKK_CHUK_ST	P35222	CTNNB1	O15111	CHUK	S718	Y716C	716	Missense	proximal	-2	no	216.341	215.871	EPSD	COSMIC	187.474	Down-regulation
Other_IKK_CHUK_ST	P35222	CTNNB1	O15111	CHUK	S718	H720P	720	Missense	proximal	2	no	216.341	216.960	EPSD	COSMIC	187.474	Up-regulation
Other_IKK_CHUK_ST	P35222	CTNNB1	O15111	CHUK	S718	R717C	717	Missense	proximal	-1	no	216.341	217.116	EPSD	COSMIC	187.474	Up-regulation
Other_IKK_CHUK_ST	P35222	CTNNB1	O15111	CHUK	S718	S715R	715	Missense	distal	-3	no	216.341	235.319	EPSD	COSMIC	187.474	Up-regulation
Other_IKK_CHUK_ST	P35222	CTNNB1	O15111	CHUK	S718	D712N	712	Missense	distal	-6	no	216.341	221.217	EPSD	COSMIC	187.474	Up-regulation
Other_IKK_CHUK_ST	P35222	CTNNB1	O15111	CHUK	S718	P714S	714	Missense	distal	-4	no	216.341	223.958	EPSD	COSMIC	187.474	Up-regulation
Other_IKK_CHUK_ST	P35222	CTNNB1	O15111	CHUK	S718	Y724S	724	Missense	distal	6	no	216.341	217.122	EPSD	COSMIC	187.474	Up-regulation
Other_IKK_CHUK_ST	P35222	CTNNB1	O15111	CHUK	S718	G723S	723	Missense	distal	5	no	216.341	214.965	EPSD	COSMIC	187.474	Down-regulation
Other_IKK_CHUK_ST	P35222	CTNNB1	O15111	CHUK	S718	Y724C	724	Missense	distal	6	no	216.341	222.583	EPSD	COSMIC	187.474	Up-regulation
Other_IKK_CHUK_ST	P35222	CTNNB1	O15111	CHUK	S718	G725D	725	Missense	distal	7	no	216.341	208.302	EPSD	COSMIC	187.474	Down-regulation
Other_IKK_CHUK_ST	Q9C0C7	AMBRA1	O15111	CHUK	S394	R392H	392	Missense	proximal	-2	no	193.505	186.379	EPSD	COSMIC	187.474	Loss
Other_IKK_CHUK_ST	Q9C0C7	AMBRA1	O15111	CHUK	S394	R393H	393	Missense	proximal	-1	no	193.505	194.751	EPSD	COSMIC	187.474	Up-regulation
Other_IKK_CHUK_ST	Q9C0C7	AMBRA1	O15111	CHUK	S394	L395F	395	Missense	proximal	1	no	193.505	184.527	EPSD	COSMIC	187.474	Loss
Other_IKK_CHUK_ST	Q9C0C7	AMBRA1	O15111	CHUK	S394	S400C	400	Missense	distal	6	no	193.505	198.966	EPSD	COSMIC	187.474	Up-regulation
Other_IKK_CHUK_ST	Q9C0C7	AMBRA1	O15111	CHUK	S797	R795Q	795	Missense	proximal	-2	no	195.018	203.762	EPSD	COSMIC	187.474	Up-regulation
Other_IKK_CHUK_ST	Q9C0C7	AMBRA1	O15111	CHUK	S797	R795W	795	Missense	proximal	-2	no	195.018	179.366	EPSD	COSMIC	187.474	Loss
Other_IKK_CHUK_ST	Q9C0C7	AMBRA1	O15111	CHUK	S797	A790P	790	Missense	distal	-7	no	195.018	195.137	EPSD	COSMIC	187.474	Up-regulation
Other_IKK_CHUK_ST	Q9C0C7	AMBRA1	O15111	CHUK	S797	R803H	803	Missense	distal	6	no	195.018	198.663	EPSD	COSMIC	187.474	Up-regulation
Other_IKK_CHUK_ST	Q9C0C7	AMBRA1	O15111	CHUK	S797	R792C	792	Missense	distal	-5	no	195.018	194.170	EPSD	COSMIC;CCLE	187.474	Down-regulation
Other_IKK_CHUK_ST	Q9C0C7	AMBRA1	O15111	CHUK	S800	R803H	803	Missense	distal	3	no	165.864	191.993	EPSD	COSMIC	187.474	Gain
Other_IKK_CHUK_ST	Q9C0C7	AMBRA1	O15111	CHUK	S948	L949Q	949	Missense	proximal	1	no	219.257	202.525	EPSD	COSMIC	187.474	Down-regulation
Other_IKK_CHUK_ST	Q9C0C7	AMBRA1	O15111	CHUK	S948	I945V	945	Missense	distal	-3	no	219.257	231.591	EPSD	COSMIC	187.474	Up-regulation
Other_IKK_CHUK_ST	Q9C0C7	AMBRA1	O15111	CHUK	S948	N943D	943	Missense	distal	-5	no	219.257	237.305	EPSD	COSMIC	187.474	Up-regulation
Other_IKK_CHUK_ST	Q9C0C7	AMBRA1	O15111	CHUK	S948	S946L	946	Missense	proximal	-2	no	219.257	230.798	EPSD	COSMIC;CCLE	187.474	Up-regulation
Other_IKK_CHUK_ST	Q9C0C7	AMBRA1	O15111	CHUK	S948	M952I	952	Missense	distal	4	no	219.257	223.554	EPSD	COSMIC	187.474	Up-regulation
Other_IKK_CHUK_ST	Q9C0C7	AMBRA1	O15111	CHUK	S948	S950F	950	Missense	proximal	2	no	219.257	219.010	EPSD	COSMIC	187.474	Down-regulation
Other_IKK_CHUK_ST	Q9C0C7	AMBRA1	O15111	CHUK	S948	G941C	941	Missense	distal	-7	no	219.257	214.721	EPSD	COSMIC	187.474	Down-regulation
Other_IKK_CHUK_ST	Q9C0C7	AMBRA1	O15111	CHUK	S948	G953V	953	Missense	distal	5	no	219.257	222.392	EPSD	COSMIC	187.474	Up-regulation
Other_IKK_CHUK_ST	Q9C0C7	AMBRA1	O15111	CHUK	S948	A944V	944	Missense	distal	-4	no	219.257	214.738	EPSD	COSMIC	187.474	Down-regulation
Other_IKK_CHUK_ST	Q9C0C7	AMBRA1	O15111	CHUK	S1192	S1192F	1192	Missense	central	0	yes	199.212	0.000	EPSD	COSMIC	187.474	Loss
Other_IKK_CHUK_ST	Q9C0C7	AMBRA1	O15111	CHUK	S1192	S1191F	1191	Missense	proximal	-1	no	199.212	198.023	EPSD	COSMIC	187.474	Down-regulation
Other_IKK_CHUK_ST	Q9C0C7	AMBRA1	O15111	CHUK	S1192	Q1193E	1193	Missense	proximal	1	no	199.212	209.500	EPSD	COSMIC	187.474	Up-regulation
Other_IKK_CHUK_ST	Q9C0C7	AMBRA1	O15111	CHUK	S1192	T1194M	1194	Missense	proximal	2	no	199.212	201.161	EPSD	COSMIC	187.474	Up-regulation
Other_IKK_CHUK_ST	Q9C0C7	AMBRA1	O15111	CHUK	S1192	R1187H	1187	Missense	distal	-5	no	199.212	204.097	EPSD	COSMIC	187.474	Up-regulation
Other_IKK_CHUK_ST	Q9C0C7	AMBRA1	O15111	CHUK	S1192	S1185N	1185	Missense	distal	-7	no	199.212	199.023	EPSD	COSMIC	187.474	Down-regulation
Other_IKK_CHUK_ST	Q8N3F0	MTURN	O15111	CHUK	S58	D62N	62	Missense	distal	4	no	240.714	243.470	PhosphoSitePlus	COSMIC	187.474	Up-regulation
Other_IKK_CHUK_ST	Q8N3F0	MTURN	O15111	CHUK	S58	E61K	61	Missense	distal	3	no	240.714	241.435	PhosphoSitePlus	COSMIC;GDSC	187.474	Up-regulation
Other_IKK_CHUK_ST	Q8N3F0	MTURN	O15111	CHUK	S129	M126K	126	Missense	distal	-3	no	178.201	193.434	EPSD	COSMIC	187.474	Gain
Other_IKK_CHUK_ST	Q92793	CREBBP	O15111	CHUK	S23	F22L	22	Missense	proximal	-1	no	243.424	245.544	EPSD	COSMIC	187.474	Up-regulation
Other_IKK_CHUK_ST	Q92793	CREBBP	O15111	CHUK	S23	P20T	20	Missense	distal	-3	no	243.424	237.098	EPSD	COSMIC	187.474	Down-regulation
Other_IKK_CHUK_ST	Q92793	CREBBP	O15111	CHUK	S23	G21D	21	Missense	proximal	-2	no	243.424	246.290	EPSD	COSMIC	187.474	Up-regulation
Other_IKK_CHUK_ST	Q92793	CREBBP	O15111	CHUK	S302	N305D	305	Missense	distal	3	no	151.638	188.599	EPSD	COSMIC	187.474	Gain
Other_IKK_CHUK_ST	Q92793	CREBBP	O15111	CHUK	S306	N305D	305	Missense	proximal	-1	no	206.435	209.335	EPSD	COSMIC	187.474	Up-regulation
Other_IKK_CHUK_ST	Q92793	CREBBP	O15111	CHUK	S306	S302R	302	Missense	distal	-4	no	206.435	187.185	EPSD	COSMIC	187.474	Loss
Other_IKK_CHUK_ST	Q92793	CREBBP	O15111	CHUK	S306	S302N	302	Missense	distal	-4	no	206.435	209.546	EPSD	COSMIC	187.474	Up-regulation
Other_IKK_CHUK_ST	Q92793	CREBBP	O15111	CHUK	S306	P308S	308	Missense	proximal	2	no	206.435	202.607	EPSD	COSMIC	187.474	Down-regulation
Other_IKK_CHUK_ST	Q92793	CREBBP	O15111	CHUK	S306	N305H	305	Missense	proximal	-1	no	206.435	206.787	EPSD	COSMIC	187.474	Up-regulation
Other_IKK_CHUK_ST	Q92793	CREBBP	O15111	CHUK	S381	M388R	388	Missense	distal	7	no	194.254	200.826	EPSD	COSMIC	187.474	Up-regulation
Other_IKK_CHUK_ST	Q92793	CREBBP	O15111	CHUK	S381	R378Q	378	Missense	distal	-3	no	194.254	168.323	EPSD	COSMIC	187.474	Loss
Other_IKK_CHUK_ST	Q92793	CREBBP	O15111	CHUK	S381	N374I	374	Missense	distal	-7	no	194.254	191.785	EPSD	COSMIC	187.474	Down-regulation
Other_IKK_CHUK_ST	Q92793	CREBBP	O15111	CHUK	S750	S755N	755	Missense	distal	5	no	208.417	208.894	EPSD	COSMIC	187.474	Up-regulation
Other_IKK_CHUK_ST	Q92793	CREBBP	O15111	CHUK	S750	M747V	747	Missense	distal	-3	no	208.417	231.549	EPSD	COSMIC	187.474	Up-regulation
Other_IKK_CHUK_ST	Q92793	CREBBP	O15111	CHUK	S750	V751A	751	Missense	proximal	1	no	208.417	193.188	EPSD	COSMIC	187.474	Down-regulation
Other_IKK_CHUK_ST	Q92793	CREBBP	O15111	CHUK	S985	E982V	982	Missense	distal	-3	no	172.809	187.482	EPSD	COSMIC	187.474	Gain
Other_IKK_CHUK_ST	Q92793	CREBBP	O15111	CHUK	S1030	E1035Q	1035	Missense	distal	5	no	192.517	186.886	EPSD	COSMIC	187.474	Loss
Other_IKK_CHUK_ST	Q92793	CREBBP	O15111	CHUK	S1030	D1037N	1037	Missense	distal	7	no	192.517	188.831	EPSD	COSMIC	187.474	Down-regulation
Other_IKK_CHUK_ST	Q92793	CREBBP	O15111	CHUK	S1030	T1036A	1036	Missense	distal	6	no	192.517	197.236	EPSD	COSMIC	187.474	Up-regulation
Other_IKK_CHUK_ST	Q92793	CREBBP	O15111	CHUK	S1030	S1030F	1030	Missense	central	0	yes	192.517	0.000	EPSD	COSMIC	187.474	Loss
Other_IKK_CHUK_ST	Q92793	CREBBP	O15111	CHUK	S1043	D1037N	1037	Missense	distal	-6	no	184.096	188.972	EPSD	COSMIC	187.474	Gain
Other_IKK_CHUK_ST	Q92793	CREBBP	O15111	CHUK	S1072	A1071T	1071	Missense	proximal	-1	no	195.812	197.925	EPSD	COSMIC;GDSC;CCLE	187.474	Up-regulation
Other_IKK_CHUK_ST	Q92793	CREBBP	O15111	CHUK	S1072	S1072F	1072	Missense	central	0	yes	195.812	0.000	EPSD	COSMIC;GDSC;CCLE	187.474	Loss
Other_IKK_CHUK_ST	Q92793	CREBBP	O15111	CHUK	S1072	G1069S	1069	Missense	distal	-3	no	195.812	181.804	EPSD	COSMIC	187.474	Loss
Other_IKK_CHUK_ST	Q92793	CREBBP	O15111	CHUK	S1072	G1069R	1069	Missense	distal	-3	no	195.812	200.781	EPSD	COSMIC	187.474	Up-regulation
Other_IKK_CHUK_ST	Q92793	CREBBP	O15111	CHUK	S1072	G1069D	1069	Missense	distal	-3	no	195.812	186.762	EPSD	COSMIC	187.474	Loss
Other_IKK_CHUK_ST	Q92793	CREBBP	O15111	CHUK	S1072	Q1073E	1073	Missense	proximal	1	no	195.812	206.099	EPSD	COSMIC	187.474	Up-regulation
Other_IKK_CHUK_ST	Q92793	CREBBP	O15111	CHUK	S1072	Q1079H	1079	Missense	distal	7	no	195.812	205.210	EPSD	COSMIC;GDSC;CCLE	187.474	Up-regulation
Other_IKK_CHUK_ST	Q92793	CREBBP	O15111	CHUK	S1078	R1081H	1081	Missense	distal	3	no	172.803	198.932	EPSD	COSMIC	187.474	Gain
Other_IKK_CHUK_ST	Q92793	CREBBP	O15111	CHUK	S1382	R1378W	1378	Missense	distal	-4	no	242.216	227.767	PhosphoSitePlus;EPSD	COSMIC	187.474	Down-regulation
Other_IKK_CHUK_ST	Q92793	CREBBP	O15111	CHUK	S1382	S1388F	1388	Missense	distal	6	no	242.216	247.230	PhosphoSitePlus;EPSD	COSMIC	187.474	Up-regulation
Other_IKK_CHUK_ST	Q92793	CREBBP	O15111	CHUK	S1382	R1378L	1378	Missense	distal	-4	no	242.216	225.615	PhosphoSitePlus;EPSD	COSMIC	187.474	Down-regulation
Other_IKK_CHUK_ST	Q92793	CREBBP	O15111	CHUK	S1382	S1386C	1386	Missense	distal	4	no	242.216	234.002	PhosphoSitePlus;EPSD	COSMIC	187.474	Down-regulation
Other_IKK_CHUK_ST	Q92793	CREBBP	O15111	CHUK	S1382	G1383V	1383	Missense	proximal	1	no	242.216	255.343	PhosphoSitePlus;EPSD	COSMIC	187.474	Up-regulation
Other_IKK_CHUK_ST	Q92793	CREBBP	O15111	CHUK	S1382	R1378Q	1378	Missense	distal	-4	no	242.216	247.676	PhosphoSitePlus;EPSD	COSMIC	187.474	Up-regulation
Other_IKK_CHUK_ST	Q92793	CREBBP	O15111	CHUK	S1382	F1379V	1379	Missense	distal	-3	no	242.216	253.324	PhosphoSitePlus;EPSD	COSMIC	187.474	Up-regulation
Other_IKK_CHUK_ST	Q92793	CREBBP	O15111	CHUK	S1386	S1388F	1388	Missense	proximal	2	no	246.093	245.846	EPSD;PhosphoSitePlus	COSMIC	187.474	Down-regulation
Other_IKK_CHUK_ST	Q92793	CREBBP	O15111	CHUK	S1386	S1386C	1386	Missense	central	0	yes	246.093	0.000	EPSD;PhosphoSitePlus	COSMIC	187.474	Loss
Other_IKK_CHUK_ST	Q92793	CREBBP	O15111	CHUK	S1386	G1383V	1383	Missense	distal	-3	no	246.093	251.581	EPSD;PhosphoSitePlus	COSMIC	187.474	Up-regulation
Other_IKK_CHUK_ST	Q92793	CREBBP	O15111	CHUK	S1386	F1379V	1379	Missense	distal	-7	no	246.093	245.738	EPSD;PhosphoSitePlus	COSMIC	187.474	Down-regulation
Other_IKK_CHUK_ST	Q92793	CREBBP	O15111	CHUK	S1609	A1603S	1603	Missense	distal	-6	no	199.900	196.770	EPSD	COSMIC	187.474	Down-regulation
Other_IKK_CHUK_ST	Q92793	CREBBP	O15111	CHUK	S1609	N1612S	1612	Missense	distal	3	no	199.900	197.203	EPSD	COSMIC	187.474	Down-regulation
Other_IKK_CHUK_ST	Q92793	CREBBP	O15111	CHUK	S1609	V1613M	1613	Missense	distal	4	no	199.900	197.008	EPSD	COSMIC	187.474	Down-regulation
Other_IKK_CHUK_ST	Q92793	CREBBP	O15111	CHUK	S1609	K1606R	1606	Missense	distal	-3	no	199.900	207.282	EPSD	COSMIC	187.474	Up-regulation
Other_IKK_CHUK_ST	Q92793	CREBBP	O15111	CHUK	S1609	K1605E	1605	Missense	distal	-4	no	199.900	188.135	EPSD	COSMIC	187.474	Down-regulation
Other_IKK_CHUK_ST	Q92793	CREBBP	O15111	CHUK	S1887	P1885S	1885	Missense	proximal	-2	no	172.312	197.117	EPSD	COSMIC	187.474	Gain
Other_IKK_CHUK_ST	Q92793	CREBBP	O15111	CHUK	S2377	S2377L	2377	Missense	central	0	yes	192.886	0.000	EPSD	COSMIC	187.474	Loss
Other_IKK_CHUK_ST	Q92793	CREBBP	O15111	CHUK	S2377	H2384R	2384	Missense	distal	7	no	192.886	196.250	EPSD	COSMIC	187.474	Up-regulation
Other_IKK_CHUK_ST	Q92793	CREBBP	O15111	CHUK	S2377	P2383L	2383	Missense	distal	6	no	192.886	185.618	EPSD	COSMIC	187.474	Loss
Other_IKK_CHUK_ST	Q92793	CREBBP	O15111	CHUK	S2377	S2372W	2372	Missense	distal	-5	no	192.886	168.918	EPSD	COSMIC	187.474	Loss
Other_IKK_CHUK_ST	Q92793	CREBBP	O15111	CHUK	S2377	P2383S	2383	Missense	distal	6	no	192.886	184.085	EPSD	COSMIC	187.474	Loss
Other_IKK_CHUK_ST	Q92793	CREBBP	O15111	CHUK	S2377	H2384N	2384	Missense	distal	7	no	192.886	185.399	EPSD	COSMIC	187.474	Loss
Other_IKK_CHUK_ST	Q92793	CREBBP	O15111	CHUK	S2377	Q2379H	2379	Missense	proximal	2	no	192.886	197.401	EPSD	COSMIC	187.474	Up-regulation
Other_IKK_CHUK_ST	Q92793	CREBBP	O15111	CHUK	S2393	A2392V	2392	Missense	proximal	-1	no	197.504	198.473	EPSD	COSMIC	187.474	Up-regulation
Other_IKK_CHUK_ST	Q92793	CREBBP	O15111	CHUK	S2393	A2392T	2392	Missense	proximal	-1	no	197.504	199.618	EPSD	COSMIC	187.474	Up-regulation
Other_IKK_CHUK_ST	Q92793	CREBBP	O15111	CHUK	S2393	M2391I	2391	Missense	proximal	-2	no	197.504	207.258	EPSD	COSMIC	187.474	Up-regulation
Other_IKK_CHUK_ST	Q92793	CREBBP	O15111	CHUK	S2393	T2390N	2390	Missense	distal	-3	no	197.504	193.272	EPSD	COSMIC;GDSC;CCLE	187.474	Down-regulation
Other_IKK_CHUK_ST	Q92793	CREBBP	O15111	CHUK	S2393	I2395M	2395	Missense	proximal	2	no	197.504	198.241	EPSD	COSMIC	187.474	Up-regulation
Other_IKK_CHUK_ST	Q92793	CREBBP	O15111	CHUK	S2394	A2392V	2392	Missense	proximal	-2	no	192.098	174.029	EPSD	COSMIC	187.474	Loss
Other_IKK_CHUK_ST	Q92793	CREBBP	O15111	CHUK	S2394	A2392T	2392	Missense	proximal	-2	no	192.098	169.680	EPSD	COSMIC	187.474	Loss
Other_IKK_CHUK_ST	Q92793	CREBBP	O15111	CHUK	S2394	M2391I	2391	Missense	distal	-3	no	192.098	202.895	EPSD	COSMIC	187.474	Up-regulation
Other_IKK_CHUK_ST	Q92793	CREBBP	O15111	CHUK	S2394	T2390N	2390	Missense	distal	-4	no	192.098	212.579	EPSD	COSMIC;GDSC;CCLE	187.474	Up-regulation
Other_IKK_CHUK_ST	Q92793	CREBBP	O15111	CHUK	S2394	I2395M	2395	Missense	proximal	1	no	192.098	194.540	EPSD	COSMIC	187.474	Up-regulation
Other_IKK_CHUK_ST	Q92793	CREBBP	O15111	CHUK	S2421	P2415L	2415	Missense	distal	-6	no	224.448	216.540	EPSD	COSMIC	187.474	Down-regulation
Other_IKK_CHUK_ST	Q92793	CREBBP	O15111	CHUK	S2421	A2419V	2419	Missense	proximal	-2	no	224.448	206.379	EPSD	COSMIC	187.474	Down-regulation
Other_IKK_CHUK_ST	Q92793	CREBBP	O15111	CHUK	S2421	S2421F	2421	Missense	central	0	yes	224.448	0.000	EPSD	COSMIC;GDSC;CCLE	187.474	Loss
Other_IKK_CHUK_ST	Q92793	CREBBP	O15111	CHUK	S2422	P2415L	2415	Missense	distal	-7	no	196.661	197.224	EPSD	COSMIC	187.474	Up-regulation
Other_IKK_CHUK_ST	Q92793	CREBBP	O15111	CHUK	S2422	A2419V	2419	Missense	distal	-3	no	196.661	208.897	EPSD	COSMIC	187.474	Up-regulation
Other_IKK_CHUK_ST	Q92793	CREBBP	O15111	CHUK	S2422	D2429Y	2429	Missense	distal	7	no	196.661	196.858	EPSD	COSMIC	187.474	Up-regulation
Other_IKK_CHUK_ST	Q92793	CREBBP	O15111	CHUK	S2422	S2421F	2421	Missense	proximal	-1	no	196.661	195.472	EPSD	COSMIC;GDSC;CCLE	187.474	Down-regulation
Other_IKK_CHUK_ST	Q92793	CREBBP	O15111	CHUK	S2425	A2419V	2419	Missense	distal	-6	no	228.994	227.477	EPSD	COSMIC	187.474	Down-regulation
Other_IKK_CHUK_ST	Q92793	CREBBP	O15111	CHUK	S2425	D2429Y	2429	Missense	distal	4	no	228.994	227.896	EPSD	COSMIC	187.474	Down-regulation
Other_IKK_CHUK_ST	Q92793	CREBBP	O15111	CHUK	S2425	S2421F	2421	Missense	distal	-4	no	228.994	201.325	EPSD	COSMIC;GDSC;CCLE	187.474	Down-regulation
Other_IKK_CHUK_ST	Q92793	CREBBP	O15111	CHUK	T2430	D2429Y	2429	Missense	proximal	-1	no	192.951	190.040	EPSD	COSMIC	187.474	Down-regulation
Other_IKK_CHUK_ST	Q92793	CREBBP	O15111	CHUK	T2430	E2436Q	2436	Missense	distal	6	no	192.951	188.322	EPSD	COSMIC	187.474	Down-regulation
Other_IKK_CHUK_ST	Q92793	CREBBP	O15111	CHUK	T2430	D2433G	2433	Missense	distal	3	no	192.951	165.212	EPSD	COSMIC	187.474	Loss
Other_IKK_CHUK_ST	P42345	MTOR	O15111	CHUK	S31	E34K	34	Missense	distal	3	no	196.279	197.000	EPSD	COSMIC	187.474	Up-regulation
Other_IKK_CHUK_ST	P42345	MTOR	O15111	CHUK	S31	E34D	34	Missense	distal	3	no	196.279	242.046	EPSD	COSMIC	187.474	Up-regulation
Other_IKK_CHUK_ST	P42345	MTOR	O15111	CHUK	S31	R32W	32	Missense	proximal	1	no	196.279	210.190	EPSD	COSMIC	187.474	Up-regulation
Other_IKK_CHUK_ST	P42345	MTOR	O15111	CHUK	S31	S27N	27	Missense	distal	-4	no	196.279	199.390	EPSD	COSMIC	187.474	Up-regulation
Other_IKK_CHUK_ST	P42345	MTOR	O15111	CHUK	S581	L586F	586	Missense	distal	5	no	221.298	225.535	EPSD	COSMIC	187.474	Up-regulation
Other_IKK_CHUK_ST	P42345	MTOR	O15111	CHUK	S581	T588A	588	Missense	distal	7	no	221.298	217.686	EPSD	COSMIC	187.474	Down-regulation
Other_IKK_CHUK_ST	P42345	MTOR	O15111	CHUK	S581	D578Y	578	Missense	distal	-3	no	221.298	222.225	EPSD	COSMIC	187.474	Up-regulation
Other_IKK_CHUK_ST	P42345	MTOR	O15111	CHUK	S581	T588M	588	Missense	distal	7	no	221.298	218.548	EPSD	COSMIC;GDSC;CCLE	187.474	Down-regulation
Other_IKK_CHUK_ST	P42345	MTOR	O15111	CHUK	S831	A835T	835	Missense	distal	4	no	189.489	192.176	EPSD	COSMIC	187.474	Up-regulation
Other_IKK_CHUK_ST	P42345	MTOR	O15111	CHUK	S831	D826Y	826	Missense	distal	-5	no	189.489	174.473	EPSD	COSMIC	187.474	Loss
Other_IKK_CHUK_ST	P42345	MTOR	O15111	CHUK	S831	D830G	830	Missense	proximal	-1	no	189.489	185.738	EPSD	COSMIC	187.474	Loss
Other_IKK_CHUK_ST	P42345	MTOR	O15111	CHUK	S831	D830H	830	Missense	proximal	-1	no	189.489	186.940	EPSD	COSMIC	187.474	Loss
Other_IKK_CHUK_ST	P42345	MTOR	O15111	CHUK	S831	L828F	828	Missense	distal	-3	no	189.489	194.112	EPSD	COSMIC	187.474	Up-regulation
Other_IKK_CHUK_ST	P42345	MTOR	O15111	CHUK	S909	D911Y	911	Missense	proximal	2	no	187.512	187.812	EPSD	COSMIC	187.474	Up-regulation
Other_IKK_CHUK_ST	P42345	MTOR	O15111	CHUK	S909	D907N	907	Missense	proximal	-2	no	187.512	186.714	EPSD	COSMIC	187.474	Loss
Other_IKK_CHUK_ST	P42345	MTOR	O15111	CHUK	S909	G904V	904	Missense	distal	-5	no	187.512	184.063	EPSD	COSMIC	187.474	Loss
Other_IKK_CHUK_ST	P42345	MTOR	O15111	CHUK	S1171	S1178F	1178	Missense	distal	7	no	191.963	198.885	EPSD	COSMIC;CCLE	187.474	Up-regulation
Other_IKK_CHUK_ST	P42345	MTOR	O15111	CHUK	S1171	Q1165H	1165	Missense	distal	-6	no	191.963	198.973	EPSD	COSMIC	187.474	Up-regulation
Other_IKK_CHUK_ST	P42345	MTOR	O15111	CHUK	S1171	R1170H	1170	Missense	proximal	-1	no	191.963	193.209	EPSD	COSMIC	187.474	Up-regulation
Other_IKK_CHUK_ST	P42345	MTOR	O15111	CHUK	S1171	R1170P	1170	Missense	proximal	-1	no	191.963	192.521	EPSD	COSMIC	187.474	Up-regulation
Other_IKK_CHUK_ST	P42345	MTOR	O15111	CHUK	S1171	S1178P	1178	Missense	distal	7	no	191.963	198.628	EPSD	COSMIC	187.474	Up-regulation
Other_IKK_CHUK_ST	P42345	MTOR	O15111	CHUK	S1171	M1174L	1174	Missense	distal	3	no	191.963	185.974	EPSD	COSMIC	187.474	Loss
Other_IKK_CHUK_ST	P42345	MTOR	O15111	CHUK	S1179	F1182S	1182	Missense	distal	3	no	160.083	194.342	EPSD	COSMIC	187.474	Gain
Other_IKK_CHUK_ST	P42345	MTOR	O15111	CHUK	S1297	S1295L	1295	Missense	proximal	-2	no	180.835	192.376	EPSD	COSMIC	187.474	Gain
Other_IKK_CHUK_ST	P42345	MTOR	O15111	CHUK	S1299	S1297L	1297	Missense	proximal	-2	no	182.904	194.445	EPSD	COSMIC	187.474	Gain
Other_IKK_CHUK_ST	P42345	MTOR	O15111	CHUK	S1415	T1409P	1409	Missense	distal	-6	no	232.439	239.583	PhosphoSitePlus	COSMIC	187.474	Up-regulation
Other_IKK_CHUK_ST	P42345	MTOR	O15111	CHUK	S1415	P1410L	1410	Missense	distal	-5	no	232.439	228.497	PhosphoSitePlus	COSMIC	187.474	Down-regulation
Other_IKK_CHUK_ST	P42345	MTOR	O15111	CHUK	S1415	S1415C	1415	Missense	central	0	yes	232.439	0.000	PhosphoSitePlus	COSMIC	187.474	Loss
Other_IKK_CHUK_ST	P42345	MTOR	O15111	CHUK	S1415	E1414K	1414	Missense	proximal	-1	no	232.439	232.988	PhosphoSitePlus	COSMIC	187.474	Up-regulation
Other_IKK_CHUK_ST	P42345	MTOR	O15111	CHUK	S1855	E1850D	1850	Missense	distal	-5	no	166.835	192.036	EPSD	COSMIC	187.474	Gain
Other_IKK_CHUK_ST	P42345	MTOR	O15111	CHUK	S1982	T1977S	1977	Missense	distal	-5	no	195.338	201.020	EPSD	COSMIC	187.474	Up-regulation
Other_IKK_CHUK_ST	P42345	MTOR	O15111	CHUK	S1982	R1987W	1987	Missense	distal	5	no	195.338	199.875	EPSD	COSMIC	187.474	Up-regulation
Other_IKK_CHUK_ST	P42345	MTOR	O15111	CHUK	S1982	T1983A	1983	Missense	proximal	1	no	195.338	189.663	EPSD	COSMIC	187.474	Down-regulation
Other_IKK_CHUK_ST	P42345	MTOR	O15111	CHUK	S1982	H1988Y	1988	Missense	distal	6	no	195.338	187.776	EPSD	COSMIC	187.474	Down-regulation
Other_IKK_CHUK_ST	P42345	MTOR	O15111	CHUK	S2155	I2156T	2156	Missense	proximal	1	no	212.892	204.678	EPSD	COSMIC	187.474	Down-regulation
Other_IKK_CHUK_ST	P42345	MTOR	O15111	CHUK	S2155	R2152H	2152	Missense	distal	-3	no	212.892	200.202	EPSD	COSMIC	187.474	Down-regulation
Other_IKK_CHUK_ST	P42345	MTOR	O15111	CHUK	S2155	I2150V	2150	Missense	distal	-5	no	212.892	217.798	EPSD	COSMIC	187.474	Up-regulation
Other_IKK_CHUK_ST	P42345	MTOR	O15111	CHUK	S2155	Q2154E	2154	Missense	proximal	-1	no	212.892	213.009	EPSD	COSMIC	187.474	Up-regulation
Other_IKK_CHUK_ST	P42345	MTOR	O15111	CHUK	S2155	P2158L	2158	Missense	distal	3	no	212.892	208.546	EPSD	COSMIC	187.474	Down-regulation
Other_IKK_CHUK_ST	P42345	MTOR	O15111	CHUK	S2155	P2158S	2158	Missense	distal	3	no	212.892	211.316	EPSD	COSMIC	187.474	Down-regulation
Other_IKK_CHUK_ST	P42345	MTOR	O15111	CHUK	S2159	I2156T	2156	Missense	distal	-3	no	195.552	195.933	EPSD	COSMIC	187.474	Up-regulation
Other_IKK_CHUK_ST	P42345	MTOR	O15111	CHUK	S2159	R2152H	2152	Missense	distal	-7	no	195.552	197.895	EPSD	COSMIC	187.474	Up-regulation
Other_IKK_CHUK_ST	P42345	MTOR	O15111	CHUK	S2159	Q2154E	2154	Missense	distal	-5	no	195.552	190.302	EPSD	COSMIC	187.474	Down-regulation
Other_IKK_CHUK_ST	P42345	MTOR	O15111	CHUK	S2159	P2158L	2158	Missense	proximal	-1	no	195.552	197.544	EPSD	COSMIC	187.474	Up-regulation
Other_IKK_CHUK_ST	P42345	MTOR	O15111	CHUK	S2159	P2158S	2158	Missense	proximal	-1	no	195.552	196.613	EPSD	COSMIC	187.474	Up-regulation
Other_IKK_CHUK_ST	P42345	MTOR	O15111	CHUK	S2215	P2213L	2213	Missense	proximal	-2	no	161.188	197.534	EPSD	COSMIC	187.474	Gain
Other_IKK_CHUK_ST	Q9Y618	NCOR2	O15111	CHUK	S140	G143D	143	Missense	distal	3	no	178.092	205.831	EPSD	COSMIC	187.474	Gain
Other_IKK_CHUK_ST	Q9Y618	NCOR2	O15111	CHUK	S592	Q599K	599	Missense	distal	7	no	196.406	204.515	EPSD	COSMIC	187.474	Up-regulation
Other_IKK_CHUK_ST	Q9Y618	NCOR2	O15111	CHUK	S592	T597A	597	Missense	distal	5	no	196.406	195.148	EPSD	COSMIC	187.474	Down-regulation
Other_IKK_CHUK_ST	Q9Y618	NCOR2	O15111	CHUK	S592	T597I	597	Missense	distal	5	no	196.406	192.469	EPSD	COSMIC	187.474	Down-regulation
Other_IKK_CHUK_ST	Q9Y618	NCOR2	O15111	CHUK	S592	A587T	587	Missense	distal	-5	no	196.406	205.985	EPSD	COSMIC	187.474	Up-regulation
Other_IKK_CHUK_ST	Q9Y618	NCOR2	O15111	CHUK	S745	A740V	740	Missense	distal	-5	no	192.899	192.320	EPSD	COSMIC	187.474	Down-regulation
Other_IKK_CHUK_ST	Q9Y618	NCOR2	O15111	CHUK	S745	S746P	746	Missense	proximal	1	no	192.899	198.300	EPSD	COSMIC	187.474	Up-regulation
Other_IKK_CHUK_ST	Q9Y618	NCOR2	O15111	CHUK	S1118	P1115L	1115	Missense	distal	-3	no	264.378	254.274	EPSD	COSMIC	187.474	Down-regulation
Other_IKK_CHUK_ST	Q9Y618	NCOR2	O15111	CHUK	S1118	V1125M	1125	Missense	distal	7	no	264.378	257.271	EPSD	COSMIC	187.474	Down-regulation
Other_IKK_CHUK_ST	Q9Y618	NCOR2	O15111	CHUK	S1134	Q1129K	1129	Missense	distal	-5	no	204.615	208.757	EPSD	COSMIC	187.474	Up-regulation
Other_IKK_CHUK_ST	Q9Y618	NCOR2	O15111	CHUK	S1134	R1128W	1128	Missense	distal	-6	no	204.615	202.685	EPSD	COSMIC	187.474	Down-regulation
Other_IKK_CHUK_ST	Q9Y618	NCOR2	O15111	CHUK	S1210	R1204H	1204	Missense	distal	-6	no	190.548	191.770	EPSD	COSMIC	187.474	Up-regulation
Other_IKK_CHUK_ST	Q9Y618	NCOR2	O15111	CHUK	S1210	L1208Q	1208	Missense	proximal	-2	no	190.548	198.454	EPSD	COSMIC	187.474	Up-regulation
Other_IKK_CHUK_ST	Q9Y618	NCOR2	O15111	CHUK	S1210	R1204C	1204	Missense	distal	-6	no	190.548	189.208	EPSD	COSMIC	187.474	Down-regulation
Other_IKK_CHUK_ST	Q9Y618	NCOR2	O15111	CHUK	S1331	A1329V	1329	Missense	proximal	-2	no	205.660	187.591	EPSD	COSMIC	187.474	Down-regulation
Other_IKK_CHUK_ST	Q9Y618	NCOR2	O15111	CHUK	S1603	P1597H	1597	Missense	distal	-6	no	214.079	215.801	EPSD	COSMIC	187.474	Up-regulation
Other_IKK_CHUK_ST	Q9Y618	NCOR2	O15111	CHUK	S1603	E1599D	1599	Missense	distal	-4	no	214.079	217.537	EPSD	COSMIC	187.474	Up-regulation
Other_IKK_CHUK_ST	Q9Y618	NCOR2	O15111	CHUK	S1727	L1730F	1730	Missense	distal	3	no	195.257	163.768	EPSD	COSMIC	187.474	Loss
Other_IKK_CHUK_ST	Q9Y618	NCOR2	O15111	CHUK	S1727	S1726I	1726	Missense	proximal	-1	no	195.257	193.434	EPSD	COSMIC	187.474	Down-regulation
Other_IKK_CHUK_ST	Q9Y618	NCOR2	O15111	CHUK	S1727	S1727F	1727	Missense	central	0	yes	195.257	0.000	EPSD	COSMIC	187.474	Loss
Other_IKK_CHUK_ST	Q9Y618	NCOR2	O15111	CHUK	S1800	T1794M	1794	Missense	distal	-6	no	184.440	188.944	EPSD	COSMIC	187.474	Gain
Other_IKK_CHUK_ST	Q9Y618	NCOR2	O15111	CHUK	S1821	T1827N	1827	Missense	distal	6	no	182.530	191.282	EPSD	COSMIC	187.474	Gain
Other_IKK_CHUK_ST	Q9Y618	NCOR2	O15111	CHUK	S1825	R1818S	1818	Missense	distal	-7	no	189.864	194.755	EPSD	COSMIC	187.474	Up-regulation
Other_IKK_CHUK_ST	Q9Y618	NCOR2	O15111	CHUK	S1825	T1827N	1827	Missense	proximal	2	no	189.864	192.767	EPSD	COSMIC	187.474	Up-regulation
Other_IKK_CHUK_ST	Q9Y618	NCOR2	O15111	CHUK	S2025	S2027C	2027	Missense	proximal	2	no	194.797	198.842	EPSD	COSMIC	187.474	Up-regulation
Other_IKK_CHUK_ST	Q9Y618	NCOR2	O15111	CHUK	S2025	S2027Y	2027	Missense	proximal	2	no	194.797	198.086	EPSD	COSMIC	187.474	Up-regulation
Other_IKK_CHUK_ST	Q9Y618	NCOR2	O15111	CHUK	S2057	S2054N	2054	Missense	distal	-3	no	184.955	188.264	EPSD	COSMIC	187.474	Gain
Other_IKK_CHUK_ST	Q9Y618	NCOR2	O15111	CHUK	S2208	P2215L	2215	Missense	distal	7	no	210.292	204.763	EPSD	COSMIC	187.474	Down-regulation
Other_IKK_CHUK_ST	Q9Y618	NCOR2	O15111	CHUK	S2214	P2215L	2215	Missense	proximal	1	no	180.607	194.680	EPSD	COSMIC	187.474	Gain
Other_IKK_CHUK_ST	Q9Y618	NCOR2	O15111	CHUK	S2267	T2273I	2273	Missense	distal	6	no	206.690	213.227	EPSD	COSMIC	187.474	Up-regulation
Other_IKK_CHUK_ST	Q9Y618	NCOR2	O15111	CHUK	S2269	T2273I	2273	Missense	distal	4	no	189.107	192.454	EPSD	COSMIC	187.474	Up-regulation
Other_IKK_CHUK_ST	Q9Y618	NCOR2	O15111	CHUK	S2418	A2411V	2411	Missense	distal	-7	no	222.844	222.319	EPSD	COSMIC	187.474	Down-regulation
Other_IKK_CHUK_ST	Q04206	RELA	O15111	CHUK	S238	S240L	240	Missense	proximal	2	no	190.680	190.348	EPSD	COSMIC	187.474	Down-regulation
Other_IKK_CHUK_ST	Q04206	RELA	O15111	CHUK	S281	D277N	277	Missense	distal	-4	no	176.952	196.611	EPSD	COSMIC;CCLE	187.474	Gain
Other_IKK_CHUK_ST	Q04206	RELA	O15111	CHUK	S311	K314N	314	Missense	distal	3	no	185.513	193.598	EPSD	COSMIC	187.474	Gain
Other_IKK_CHUK_ST	Q04206	RELA	O15111	CHUK	S311	T305A	305	Missense	distal	-6	no	185.513	189.382	EPSD	COSMIC	187.474	Gain
Other_IKK_CHUK_ST	Q04206	RELA	O15111	CHUK	S338	P334S	334	Missense	distal	-4	no	202.094	209.711	EPSD	COSMIC	187.474	Up-regulation
Other_IKK_CHUK_ST	Q04206	RELA	O15111	CHUK	S529	G522E	522	Missense	distal	-7	no	209.821	207.593	EPSD	COSMIC	187.474	Down-regulation
Other_IKK_CHUK_ST	Q04206	RELA	O15111	CHUK	S529	F534L	534	Missense	distal	5	no	209.821	205.584	EPSD	COSMIC	187.474	Down-regulation
Other_IKK_CHUK_ST	Q04206	RELA	O15111	CHUK	S536	F534L	534	Missense	proximal	-2	no	262.961	262.032	PhosphoSitePlus	COSMIC	187.474	Down-regulation
Other_IKK_CHUK_ST	Q86VP1	TAX1BP1	O15111	CHUK	S254	D253G	253	Missense	proximal	-1	no	237.788	234.037	EPSD	COSMIC	187.474	Down-regulation
Other_IKK_CHUK_ST	Q86VP1	TAX1BP1	O15111	CHUK	S345	S344F	344	Missense	proximal	-1	no	228.914	227.724	EPSD	COSMIC	187.474	Down-regulation
Other_IKK_CHUK_ST	Q86VP1	TAX1BP1	O15111	CHUK	S499	D504N	504	Missense	distal	5	no	220.742	219.172	EPSD	COSMIC	187.474	Down-regulation
Other_IKK_CHUK_ST	Q86VP1	TAX1BP1	O15111	CHUK	S499	S499F	499	Missense	central	0	yes	220.742	0.000	EPSD	COSMIC	187.474	Loss
Other_IKK_CHUK_ST	Q86VP1	TAX1BP1	O15111	CHUK	S499	S501F	501	Missense	proximal	2	no	220.742	220.495	EPSD	COSMIC	187.474	Down-regulation
Other_IKK_CHUK_ST	Q86VP1	TAX1BP1	O15111	CHUK	S501	D504N	504	Missense	distal	3	no	192.712	155.751	EPSD	COSMIC	187.474	Loss
Other_IKK_CHUK_ST	Q86VP1	TAX1BP1	O15111	CHUK	S501	S499F	499	Missense	proximal	-2	no	192.712	205.182	EPSD	COSMIC	187.474	Up-regulation
Other_IKK_CHUK_ST	Q86VP1	TAX1BP1	O15111	CHUK	S501	S501F	501	Missense	central	0	yes	192.712	0.000	EPSD	COSMIC	187.474	Loss
Other_IKK_CHUK_ST	Q86VP1	TAX1BP1	O15111	CHUK	S501	P507S	507	Missense	distal	6	no	192.712	183.910	EPSD	COSMIC	187.474	Loss
Other_IKK_CHUK_ST	Q86VP1	TAX1BP1	O15111	CHUK	S666	S666R	666	Missense	central	0	yes	206.863	0.000	EPSD	COSMIC	187.474	Loss
Other_IKK_CHUK_ST	Q86VP1	TAX1BP1	O15111	CHUK	S666	P665S	665	Missense	proximal	-1	no	206.863	207.924	EPSD	COSMIC	187.474	Up-regulation
Other_IKK_CHUK_ST	Q86VP1	TAX1BP1	O15111	CHUK	S666	G668V	668	Missense	proximal	2	no	206.863	203.335	EPSD	COSMIC;GDSC;CCLE	187.474	Down-regulation
Other_IKK_CHUK_ST	Q86VP1	TAX1BP1	O15111	CHUK	S666	P661H	661	Missense	distal	-5	no	206.863	204.024	EPSD	COSMIC	187.474	Down-regulation
Other_IKK_CHUK_ST	Q86VP1	TAX1BP1	O15111	CHUK	S683	P685H	685	Missense	proximal	2	no	203.413	202.794	EPSD	COSMIC	187.474	Down-regulation
Other_IKK_CHUK_ST	Q86VP1	TAX1BP1	O15111	CHUK	S683	R680Q	680	Missense	distal	-3	no	203.413	177.482	EPSD	COSMIC	187.474	Loss
Other_IKK_CHUK_ST	Q86VP1	TAX1BP1	O15111	CHUK	S691	P685H	685	Missense	distal	-6	no	206.607	208.329	EPSD	COSMIC	187.474	Up-regulation
Other_IKK_CHUK_ST	Q86VP1	TAX1BP1	O15111	CHUK	S691	D693N	693	Missense	proximal	2	no	206.607	206.575	EPSD	COSMIC	187.474	Down-regulation
Other_IKK_CHUK_ST	Q86VP1	TAX1BP1	O15111	CHUK	S691	D693H	693	Missense	proximal	2	no	206.607	206.826	EPSD	COSMIC	187.474	Up-regulation
Other_IKK_CHUK_ST	Q86VP1	TAX1BP1	O15111	CHUK	S722	F718L	718	Missense	distal	-4	no	267.749	259.567	EPSD	COSMIC	187.474	Down-regulation
Other_IKK_CHUK_ST	Q15717	ELAVL1	O15111	CHUK	S42	E47Q	47	Missense	distal	5	no	193.084	187.454	EPSD	COSMIC	187.474	Loss
Other_IKK_CHUK_ST	Q15717	ELAVL1	O15111	CHUK	S242	C245G	245	Missense	distal	3	no	195.762	240.969	EPSD	COSMIC;CCLE	187.474	Up-regulation
Other_IKK_CHUK_ST	Q15717	ELAVL1	O15111	CHUK	S304	R309C	309	Missense	distal	5	no	229.646	234.142	PhosphoSitePlus	COSMIC	187.474	Up-regulation
Other_IKK_CHUK_ST	Q15717	ELAVL1	O15111	CHUK	S304	A299V	299	Missense	distal	-5	no	229.646	229.067	PhosphoSitePlus	COSMIC;GDSC;CCLE	187.474	Down-regulation
Other_IKK_CHUK_ST	Q15717	ELAVL1	O15111	CHUK	S304	A301V	301	Missense	distal	-3	no	229.646	241.882	PhosphoSitePlus	COSMIC	187.474	Up-regulation
Other_IKK_CHUK_ST	Q15717	ELAVL1	O15111	CHUK	S318	H325Y	325	Missense	distal	7	no	233.552	229.947	EPSD	COSMIC	187.474	Down-regulation
Other_IKK_CHUK_ST	Q15717	ELAVL1	O15111	CHUK	S318	K323R	323	Missense	distal	5	no	233.552	233.236	EPSD	COSMIC	187.474	Down-regulation
Other_IKK_CHUK_ST	P24385	CCND1	O15111	CHUK	S41	Y44D	44	Missense	distal	3	no	157.040	212.319	EPSD	COSMIC	187.474	Gain
Other_IKK_CHUK_ST	P24385	CCND1	O15111	CHUK	S43	A39S	39	Missense	distal	-4	no	172.632	189.126	EPSD	COSMIC	187.474	Gain
Other_IKK_CHUK_ST	P24385	CCND1	O15111	CHUK	S197	K194R	194	Missense	distal	-3	no	194.072	201.453	EPSD	COSMIC	187.474	Up-regulation
Other_IKK_CHUK_ST	P24385	CCND1	O15111	CHUK	S197	N198S	198	Missense	proximal	1	no	194.072	195.089	EPSD	COSMIC	187.474	Up-regulation
Other_IKK_CHUK_ST	P24385	CCND1	O15111	CHUK	S197	S201F	201	Missense	distal	4	no	194.072	192.411	EPSD	COSMIC	187.474	Down-regulation
Other_IKK_CHUK_ST	P24385	CCND1	O15111	CHUK	S197	P199L	199	Missense	proximal	2	no	194.072	189.911	EPSD	COSMIC	187.474	Down-regulation
Other_IKK_CHUK_ST	P24385	CCND1	O15111	CHUK	S197	P199R	199	Missense	proximal	2	no	194.072	191.605	EPSD	COSMIC	187.474	Down-regulation
Other_IKK_CHUK_ST	P24385	CCND1	O15111	CHUK	T286	D292G	292	Missense	distal	6	no	205.012	202.642	PhosphoSitePlus	COSMIC	187.474	Down-regulation
Other_IKK_CHUK_ST	P24385	CCND1	O15111	CHUK	T286	T286P	286	Missense	central	0	yes	205.012	0.000	PhosphoSitePlus	COSMIC	187.474	Loss
Other_IKK_CHUK_ST	P24385	CCND1	O15111	CHUK	T286	A284V	284	Missense	proximal	-2	no	205.012	186.943	PhosphoSitePlus	COSMIC	187.474	Loss
Other_IKK_CHUK_ST	P24385	CCND1	O15111	CHUK	T286	E280V	280	Missense	distal	-6	no	205.012	204.355	PhosphoSitePlus	COSMIC;CCLE	187.474	Down-regulation
Other_IKK_CHUK_ST	P24385	CCND1	O15111	CHUK	T286	R291W	291	Missense	distal	5	no	205.012	209.549	PhosphoSitePlus	COSMIC;GDSC;CCLE	187.474	Up-regulation
Other_IKK_CHUK_ST	P24385	CCND1	O15111	CHUK	T286	R291L	291	Missense	distal	5	no	205.012	203.818	PhosphoSitePlus	COSMIC;GDSC;CCLE	187.474	Down-regulation
Other_IKK_CHUK_ST	P24385	CCND1	O15111	CHUK	T286	V290G	290	Missense	distal	4	no	205.012	197.896	PhosphoSitePlus	COSMIC	187.474	Down-regulation
Other_IKK_CHUK_ST	P20749	BCL3	O15111	CHUK	S448	P444Q	444	Missense	distal	-4	no	198.077	191.904	EPSD	COSMIC	187.474	Down-regulation
Other_IKK_CHUK_ST	O43524	FOXO3	O15111	CHUK	S55	E50D	50	Missense	distal	-5	no	189.599	214.801	EPSD	COSMIC;CCLE	187.474	Up-regulation
Other_IKK_CHUK_ST	O43524	FOXO3	O15111	CHUK	S55	A53G	53	Missense	proximal	-2	no	189.599	153.663	EPSD	COSMIC	187.474	Loss
Other_IKK_CHUK_ST	O43524	FOXO3	O15111	CHUK	S75	M77L	77	Missense	proximal	2	no	199.097	196.761	EPSD	COSMIC	187.474	Down-regulation
Other_IKK_CHUK_ST	O43524	FOXO3	O15111	CHUK	S161	R154Q	154	Missense	distal	-7	no	192.266	196.624	EPSD	COSMIC;GDSC;CCLE	187.474	Up-regulation
Other_IKK_CHUK_ST	O43524	FOXO3	O15111	CHUK	S202	S203F	203	Missense	proximal	1	no	209.165	219.662	EPSD	COSMIC	187.474	Up-regulation
Other_IKK_CHUK_ST	O43524	FOXO3	O15111	CHUK	S209	S203F	203	Missense	distal	-6	no	185.204	189.216	EPSD	COSMIC	187.474	Gain
Other_IKK_CHUK_ST	O43524	FOXO3	O15111	CHUK	S215	I210S	210	Missense	distal	-5	no	183.173	203.919	EPSD	COSMIC	187.474	Gain
Other_IKK_CHUK_ST	O43524	FOXO3	O15111	CHUK	S253	S253F	253	Missense	central	0	yes	196.328	0.000	EPSD	COSMIC	187.474	Loss
Other_IKK_CHUK_ST	O43524	FOXO3	O15111	CHUK	S253	R248W	248	Missense	distal	-5	no	196.328	188.738	EPSD	COSMIC	187.474	Down-regulation
Other_IKK_CHUK_ST	O43524	FOXO3	O15111	CHUK	S330	R323C	323	Missense	distal	-7	no	198.782	198.098	EPSD	COSMIC	187.474	Down-regulation
Other_IKK_CHUK_ST	O43524	FOXO3	O15111	CHUK	S330	E332Q	332	Missense	proximal	2	no	198.782	195.218	EPSD	COSMIC;CCLE	187.474	Down-regulation
Other_IKK_CHUK_ST	O43524	FOXO3	O15111	CHUK	S330	R323H	323	Missense	distal	-7	no	198.782	201.125	EPSD	COSMIC	187.474	Up-regulation
Other_IKK_CHUK_ST	Q04864	REL	O15111	CHUK	S386	S390P	390	Missense	distal	4	no	211.624	209.695	EPSD	COSMIC	187.474	Down-regulation
Other_IKK_CHUK_ST	Q04864	REL	O15111	CHUK	S386	A384V	384	Missense	proximal	-2	no	211.624	193.555	EPSD	COSMIC	187.474	Down-regulation
Other_IKK_CHUK_ST	Q04864	REL	O15111	CHUK	S386	A384G	384	Missense	proximal	-2	no	211.624	175.688	EPSD	COSMIC	187.474	Loss
Other_IKK_CHUK_ST	Q04864	REL	O15111	CHUK	S386	S386F	386	Missense	central	0	yes	211.624	0.000	EPSD	COSMIC	187.474	Loss
Other_IKK_CHUK_ST	Q04864	REL	O15111	CHUK	S386	Y387C	387	Missense	proximal	1	no	211.624	215.359	EPSD	COSMIC	187.474	Up-regulation
Other_IKK_CHUK_ST	Q04864	REL	O15111	CHUK	S386	P393R	393	Missense	distal	7	no	211.624	216.658	EPSD	COSMIC;GDSC	187.474	Up-regulation
Other_IKK_CHUK_ST	Q04864	REL	O15111	CHUK	S516	S516N	516	Missense	central	0	yes	221.815	0.000	EPSD	COSMIC	187.474	Loss
Other_IKK_CHUK_ST	Q04864	REL	O15111	CHUK	S526	P530Q	530	Missense	distal	4	no	236.654	235.232	EPSD	COSMIC	187.474	Down-regulation
Other_IKK_CHUK_ST	Q04864	REL	O15111	CHUK	S526	L533F	533	Missense	distal	7	no	236.654	242.441	EPSD	COSMIC	187.474	Up-regulation
Other_IKK_CHUK_ST	Q04864	REL	O15111	CHUK	S557	Q558L	558	Missense	proximal	1	no	248.915	265.647	PhosphoSitePlus	COSMIC	187.474	Up-regulation
Other_IKK_CHUK_ST	Q04864	REL	O15111	CHUK	S557	S559L	559	Missense	proximal	2	no	248.915	248.583	PhosphoSitePlus	COSMIC	187.474	Down-regulation
Other_IKK_CHUK_ST	Q04864	REL	O15111	CHUK	S557	Q558R	558	Missense	proximal	1	no	248.915	239.897	PhosphoSitePlus	COSMIC	187.474	Down-regulation
Other_IKK_CHUK_ST	Q04864	REL	O15111	CHUK	S557	V554A	554	Missense	distal	-3	no	248.915	236.680	PhosphoSitePlus	COSMIC	187.474	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	O75469	NR1I2	P24941	CDK2	S114	R121S	121	Missense	distal	7	no	9.116	8.475	PhosphoSitePlus;EPSD	COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	O75469	NR1I2	P24941	CDK2	S114	E116V	116	Missense	proximal	2	no	9.116	9.142	PhosphoSitePlus;EPSD	COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	O75469	NR1I2	P24941	CDK2	T133	R127W	127	Missense	distal	-6	no	8.159	8.165	EPSD;PhosphoSitePlus	COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	O75469	NR1I2	P24941	CDK2	S200	E194K	194	Missense	distal	-6	no	11.536	11.534	EPSD;PhosphoSitePlus	COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	O75469	NR1I2	P24941	CDK2	S200	A197V	197	Missense	distal	-3	no	11.536	11.737	EPSD;PhosphoSitePlus	COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	O75469	NR1I2	P24941	CDK2	S350	A345D	345	Missense	distal	-5	no	19.111	19.144	EPSD;PhosphoSitePlus	COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	O75469	NR1I2	P24941	CDK2	S350	L348I	348	Missense	proximal	-2	no	19.111	19.182	EPSD;PhosphoSitePlus	COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	O75469	NR1I2	P24941	CDK2	S350	R353H	353	Missense	distal	3	no	19.111	18.415	EPSD;PhosphoSitePlus	COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	O75469	NR1I2	P24941	CDK2	S350	L357F	357	Missense	distal	7	no	19.111	19.783	EPSD;PhosphoSitePlus	COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	O75469	NR1I2	P24941	CDK2	T422	E427K	427	Missense	distal	5	no	13.126	12.993	EPSD	COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	O75469	NR1I2	P24941	CDK2	T422	H418Y	418	Missense	distal	-4	no	13.126	14.195	EPSD	COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	O75469	NR1I2	P24941	CDK2	T422	P419S	419	Missense	distal	-3	no	13.126	13.221	EPSD	COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	O75469	NR1I2	P24941	CDK2	T422	L424F	424	Missense	proximal	2	no	13.126	13.484	EPSD	COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	O75469	NR1I2	P24941	CDK2	T422	L424P	424	Missense	proximal	2	no	13.126	13.233	EPSD	COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	O95295	SNAPIN	P24941	CDK2	S126	S133P	133	Missense	distal	7	no	8.303	8.455	EPSD	COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	O95295	SNAPIN	P24941	CDK2	S126	G127E	127	Missense	proximal	1	no	8.303	6.450	EPSD	COSMIC	8.148	Loss
CMGC_CDK_CDK2_CDK2_ST	O95295	SNAPIN	P24941	CDK2	S126	G127R	127	Missense	proximal	1	no	8.303	5.817	EPSD	COSMIC	8.148	Loss
CMGC_CDK_CDK2_CDK2_ST	O95295	SNAPIN	P24941	CDK2	S133	S133P	133	Missense	central	0	yes	18.746	0.000	PhosphoSitePlus	COSMIC	8.148	Loss
CMGC_CDK_CDK2_CDK2_ST	Q99638	RAD9A	P24941	CDK2	S277	S272C	272	Missense	distal	-5	no	17.034	17.159	EPSD	COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	Q99638	RAD9A	P24941	CDK2	T292	S291N	291	Missense	proximal	-1	no	12.997	13.394	EPSD	COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	Q99638	RAD9A	P24941	CDK2	T292	A299D	299	Missense	distal	7	no	12.997	13.299	EPSD	COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	Q99638	RAD9A	P24941	CDK2	S336	P337L	337	Missense	proximal	1	no	14.003	4.182	EPSD	COSMIC	8.148	Loss
CMGC_CDK_CDK2_CDK2_ST	Q99638	RAD9A	P24941	CDK2	S336	G338S	338	Missense	proximal	2	no	14.003	13.952	EPSD	COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	Q99638	RAD9A	P24941	CDK2	S336	H340R	340	Missense	distal	4	no	14.003	14.120	EPSD	COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	Q99638	RAD9A	P24941	CDK2	T355	P349H	349	Missense	distal	-6	no	14.044	14.047	EPSD	COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	Q99638	RAD9A	P24941	CDK2	S375	P379S	379	Missense	distal	4	no	14.914	14.927	EPSD	COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	Q99638	RAD9A	P24941	CDK2	S380	A384V	384	Missense	distal	4	no	13.307	13.494	EPSD	COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	Q99638	RAD9A	P24941	CDK2	S380	P379S	379	Missense	proximal	-1	no	13.307	12.836	EPSD	COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	Q8IZL8	PELP1	P24941	CDK2	S477	P478Q	478	Missense	proximal	1	no	13.646	5.735	PhosphoSitePlus;EPSD	COSMIC	8.148	Loss
CMGC_CDK_CDK2_CDK2_ST	Q8IZL8	PELP1	P24941	CDK2	S477	D471A	471	Missense	distal	-6	no	13.646	13.647	PhosphoSitePlus;EPSD	COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	Q8IZL8	PELP1	P24941	CDK2	S481	P478Q	478	Missense	distal	-3	no	13.081	13.139	EPSD	COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	Q8IZL8	PELP1	P24941	CDK2	S509	P507L	507	Missense	proximal	-2	no	9.356	9.132	EPSD	COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	Q8IZL8	PELP1	P24941	CDK2	S509	H510N	510	Missense	proximal	1	no	9.356	-24.497	EPSD	COSMIC	8.148	Loss
CMGC_CDK_CDK2_CDK2_ST	Q8IZL8	PELP1	P24941	CDK2	S509	M505V	505	Missense	distal	-4	no	9.356	10.056	EPSD	COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	Q8IZL8	PELP1	P24941	CDK2	S509	G502E	502	Missense	distal	-7	no	9.356	9.122	EPSD	COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	Q8IZL8	PELP1	P24941	CDK2	S509	P507Q	507	Missense	proximal	-2	no	9.356	8.789	EPSD	COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	Q8IZL8	PELP1	P24941	CDK2	T647	P643H	643	Missense	distal	-4	no	11.719	11.115	EPSD	COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	Q8IZL8	PELP1	P24941	CDK2	T647	P648A	648	Missense	proximal	1	no	11.719	-2.684	EPSD	COSMIC	8.148	Loss
CMGC_CDK_CDK2_CDK2_ST	Q8IZL8	PELP1	P24941	CDK2	T647	P643S	643	Missense	distal	-4	no	11.719	12.074	EPSD	COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	Q8IZL8	PELP1	P24941	CDK2	T647	P640L	640	Missense	distal	-7	no	11.719	11.725	EPSD	COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	Q8IZL8	PELP1	P24941	CDK2	S658	F660S	660	Missense	proximal	2	no	16.159	15.975	EPSD	COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	Q8IZL8	PELP1	P24941	CDK2	S658	P664L	664	Missense	distal	6	no	16.159	16.160	EPSD	COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	Q8IZL8	PELP1	P24941	CDK2	S658	E655K	655	Missense	distal	-3	no	16.159	15.944	EPSD	COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	Q8IZL8	PELP1	P24941	CDK2	T745	P742S	742	Missense	distal	-3	no	14.244	14.340	EPSD	COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	Q8IZL8	PELP1	P24941	CDK2	T745	L740F	740	Missense	distal	-5	no	14.244	14.305	EPSD	COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	Q8IZL8	PELP1	P24941	CDK2	T745	G744R	744	Missense	proximal	-1	no	14.244	13.766	EPSD	COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	Q8IZL8	PELP1	P24941	CDK2	T745	I739T	739	Missense	distal	-6	no	14.244	14.242	EPSD	COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	Q8IZL8	PELP1	P24941	CDK2	T807	P808Q	808	Missense	proximal	1	no	10.151	2.239	EPSD	COSMIC	8.148	Loss
CMGC_CDK_CDK2_CDK2_ST	Q8IZL8	PELP1	P24941	CDK2	T807	G805V	805	Missense	proximal	-2	no	10.151	10.244	EPSD	COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	Q8IZL8	PELP1	P24941	CDK2	S991	A985P	985	Missense	distal	-6	no	16.884	16.885	EPSD;PhosphoSitePlus	COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	Q8IZL8	PELP1	P24941	CDK2	S991	A985T	985	Missense	distal	-6	no	16.884	16.885	EPSD;PhosphoSitePlus	COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	Q8IZL8	PELP1	P24941	CDK2	S991	E998Q	998	Missense	distal	7	no	16.884	16.685	EPSD;PhosphoSitePlus	COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	Q8IZL8	PELP1	P24941	CDK2	S1033	E1036K	1036	Missense	distal	3	no	6.905	8.990	EPSD	COSMIC	8.148	Gain
CMGC_CDK_CDK2_CDK2_ST	Q8IZL8	PELP1	P24941	CDK2	S1043	G1047E	1047	Missense	distal	4	no	14.169	14.306	EPSD	COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	Q8IZL8	PELP1	P24941	CDK2	S1043	G1041V	1041	Missense	proximal	-2	no	14.169	14.262	EPSD	COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	Q8IZL8	PELP1	P24941	CDK2	S1043	P1050S	1050	Missense	distal	7	no	14.169	14.017	EPSD	COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	Q8IZL8	PELP1	P24941	CDK2	S1043	E1036K	1036	Missense	distal	-7	no	14.169	14.032	EPSD	COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	Q8IZL8	PELP1	P24941	CDK2	S1043	E1040V	1040	Missense	distal	-3	no	14.169	14.137	EPSD	COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	Q8IZL8	PELP1	P24941	CDK2	S1073	P1078L	1078	Missense	distal	5	no	9.117	9.157	EPSD	COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	Q8IZL8	PELP1	P24941	CDK2	T1082	P1078L	1078	Missense	distal	-4	no	14.918	14.860	EPSD	COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	Q8IZL8	PELP1	P24941	CDK2	T1082	E1087Q	1087	Missense	distal	5	no	14.918	14.799	EPSD	COSMIC;CCLE	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	Q8IZL8	PELP1	P24941	CDK2	T1082	E1086K	1086	Missense	distal	4	no	14.918	15.303	EPSD	COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	Q07820	MCL1	P24941	CDK2	S64	G58S	58	Missense	distal	-6	no	12.489	12.486	EPSD;PhosphoSitePlus	COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	Q07820	MCL1	P24941	CDK2	S64	G59E	59	Missense	distal	-5	no	12.489	12.447	EPSD;PhosphoSitePlus	COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	Q07820	MCL1	P24941	CDK2	S64	P65L	65	Missense	proximal	1	no	12.489	2.668	EPSD;PhosphoSitePlus	COSMIC	8.148	Loss
CMGC_CDK_CDK2_CDK2_ST	Q07820	MCL1	P24941	CDK2	T70	D72G	72	Missense	proximal	2	no	12.831	12.951	EPSD;PhosphoSitePlus	COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	Q07820	MCL1	P24941	CDK2	T70	P65L	65	Missense	distal	-5	no	12.831	12.842	EPSD;PhosphoSitePlus	COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	Q07820	MCL1	P24941	CDK2	T70	A77V	77	Missense	distal	7	no	12.831	12.704	EPSD;PhosphoSitePlus	COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	Q07820	MCL1	P24941	CDK2	T92	P93R	93	Missense	proximal	1	no	17.383	7.585	PhosphoSitePlus;EPSD	COSMIC	8.148	Loss
CMGC_CDK_CDK2_CDK2_ST	Q07820	MCL1	P24941	CDK2	T92	F99L	99	Missense	distal	7	no	17.383	16.712	PhosphoSitePlus;EPSD	COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	Q07820	MCL1	P24941	CDK2	T92	P87L	87	Missense	distal	-5	no	17.383	17.395	PhosphoSitePlus;EPSD	COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	Q07820	MCL1	P24941	CDK2	S121	L126M	126	Missense	distal	5	no	15.691	15.959	EPSD;PhosphoSitePlus	COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	Q07820	MCL1	P24941	CDK2	S121	A116P	116	Missense	distal	-5	no	15.691	15.666	EPSD;PhosphoSitePlus	COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	Q07820	MCL1	P24941	CDK2	S121	P122L	122	Missense	proximal	1	no	15.691	5.870	EPSD;PhosphoSitePlus	COSMIC	8.148	Loss
CMGC_CDK_CDK2_CDK2_ST	Q07820	MCL1	P24941	CDK2	S150	G151H	151	Missense	proximal	1	no	7.677	8.230	EPSD	COSMIC	8.148	Gain
CMGC_CDK_CDK2_CDK2_ST	Q07820	MCL1	P24941	CDK2	T163	E169K	169	Missense	distal	6	no	13.606	13.618	EPSD;PhosphoSitePlus	COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	Q07820	MCL1	P24941	CDK2	T163	P161F	161	Missense	proximal	-2	no	13.606	12.493	EPSD;PhosphoSitePlus	COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	Q07820	MCL1	P24941	CDK2	T163	P161H	161	Missense	proximal	-2	no	13.606	12.597	EPSD;PhosphoSitePlus	COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	Q07820	MCL1	P24941	CDK2	T163	G158R	158	Missense	distal	-5	no	13.606	13.574	EPSD;PhosphoSitePlus	COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	Q07820	MCL1	P24941	CDK2	T163	G158D	158	Missense	distal	-5	no	13.606	13.584	EPSD;PhosphoSitePlus	COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	Q07820	MCL1	P24941	CDK2	S202	K197M	197	Missense	distal	-5	no	8.475	8.579	EPSD	COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	Q08999	RBL2	P24941	CDK2	S40	Q44R	44	Missense	distal	4	no	15.777	15.596	EPSD	COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	Q08999	RBL2	P24941	CDK2	T42	Q44R	44	Missense	proximal	2	no	16.099	16.199	EPSD	COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	Q08999	RBL2	P24941	CDK2	S373	R367K	367	Missense	distal	-6	no	8.209	8.207	EPSD	COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	Q08999	RBL2	P24941	CDK2	T401	Y408C	408	Missense	distal	7	no	12.401	12.773	EPSD	COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	Q08999	RBL2	P24941	CDK2	S413	P414L	414	Missense	proximal	1	no	16.455	6.634	EPSD;PhosphoSitePlus	COSMIC	8.148	Loss
CMGC_CDK_CDK2_CDK2_ST	Q08999	RBL2	P24941	CDK2	S413	P414H	414	Missense	proximal	1	no	16.455	9.696	EPSD;PhosphoSitePlus	COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	Q08999	RBL2	P24941	CDK2	S413	S413R	413	Missense	central	0	yes	16.455	0.000	EPSD;PhosphoSitePlus	COSMIC	8.148	Loss
CMGC_CDK_CDK2_CDK2_ST	Q08999	RBL2	P24941	CDK2	S413	Y408C	408	Missense	distal	-5	no	16.455	16.511	EPSD;PhosphoSitePlus	COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	Q08999	RBL2	P24941	CDK2	T417	P414L	414	Missense	distal	-3	no	14.105	14.034	EPSD;PhosphoSitePlus	COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	Q08999	RBL2	P24941	CDK2	T417	P414H	414	Missense	distal	-3	no	14.105	14.251	EPSD;PhosphoSitePlus	COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	Q08999	RBL2	P24941	CDK2	T417	S413R	413	Missense	distal	-4	no	14.105	13.507	EPSD;PhosphoSitePlus	COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	Q08999	RBL2	P24941	CDK2	S603	W606C	606	Missense	distal	3	no	15.673	11.949	EPSD	COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	Q08999	RBL2	P24941	CDK2	S603	I609N	609	Missense	distal	6	no	15.673	15.677	EPSD	COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	Q08999	RBL2	P24941	CDK2	S639	P643S	643	Missense	distal	4	no	15.320	15.333	PhosphoSitePlus;EPSD	COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	Q08999	RBL2	P24941	CDK2	T642	E648G	648	Missense	distal	6	no	15.818	15.810	EPSD;PhosphoSitePlus	COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	Q08999	RBL2	P24941	CDK2	T642	P643S	643	Missense	proximal	1	no	15.818	4.552	EPSD;PhosphoSitePlus	COSMIC	8.148	Loss
CMGC_CDK_CDK2_CDK2_ST	Q08999	RBL2	P24941	CDK2	S688	E685Q	685	Missense	distal	-3	no	12.799	12.682	EPSD;PhosphoSitePlus	COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	Q08999	RBL2	P24941	CDK2	S688	T694M	694	Missense	distal	6	no	12.799	12.772	EPSD;PhosphoSitePlus	COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	Q08999	RBL2	P24941	CDK2	T694	R697H	697	Missense	distal	3	no	14.813	14.117	EPSD;PhosphoSitePlus	COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	Q08999	RBL2	P24941	CDK2	T694	P699S	699	Missense	distal	5	no	14.813	14.712	EPSD;PhosphoSitePlus	COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	Q08999	RBL2	P24941	CDK2	T694	T694M	694	Missense	central	0	yes	14.813	0.000	EPSD;PhosphoSitePlus	COSMIC	8.148	Loss
CMGC_CDK_CDK2_CDK2_ST	Q08999	RBL2	P24941	CDK2	S952	K958R	958	Missense	distal	6	no	14.436	14.411	EPSD;PhosphoSitePlus	COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	Q08999	RBL2	P24941	CDK2	S952	S948G	948	Missense	distal	-4	no	14.436	13.764	EPSD;PhosphoSitePlus	COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	Q08999	RBL2	P24941	CDK2	S966	R963T	963	Missense	distal	-3	no	12.735	12.507	EPSD	COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	Q08999	RBL2	P24941	CDK2	S966	S972G	972	Missense	distal	6	no	12.735	12.723	EPSD	COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	Q08999	RBL2	P24941	CDK2	T986	S982N	982	Missense	distal	-4	no	15.821	15.605	EPSD	COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	Q08999	RBL2	P24941	CDK2	S1035	S1035Y	1035	Missense	central	0	yes	12.670	0.000	EPSD	COSMIC	8.148	Loss
CMGC_CDK_CDK2_CDK2_ST	Q08999	RBL2	P24941	CDK2	S1035	P1036L	1036	Missense	proximal	1	no	12.670	2.849	EPSD	COSMIC;CCLE	8.148	Loss
CMGC_CDK_CDK2_CDK2_ST	Q08999	RBL2	P24941	CDK2	S1044	R1046H	1046	Missense	proximal	2	no	15.930	15.848	EPSD;PhosphoSitePlus	COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	Q08999	RBL2	P24941	CDK2	S1044	R1046C	1046	Missense	proximal	2	no	15.930	15.917	EPSD;PhosphoSitePlus	COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	Q08999	RBL2	P24941	CDK2	S1044	I1048K	1048	Missense	distal	4	no	15.930	16.360	EPSD;PhosphoSitePlus	COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	Q08999	RBL2	P24941	CDK2	S1044	S1044F	1044	Missense	central	0	yes	15.930	0.000	EPSD;PhosphoSitePlus	COSMIC	8.148	Loss
CMGC_CDK_CDK2_CDK2_ST	Q08999	RBL2	P24941	CDK2	S1044	R1047Q	1047	Missense	distal	3	no	15.930	14.186	EPSD;PhosphoSitePlus	COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	Q08999	RBL2	P24941	CDK2	S1059	T1065K	1065	Missense	distal	6	no	16.065	16.066	EPSD	COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	Q08999	RBL2	P24941	CDK2	S1059	H1061Q	1061	Missense	proximal	2	no	16.065	16.046	EPSD	COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	Q08999	RBL2	P24941	CDK2	S1068	T1065K	1065	Missense	distal	-3	no	14.605	14.603	EPSD;PhosphoSitePlus	COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	Q08999	RBL2	P24941	CDK2	S1068	H1061Q	1061	Missense	distal	-7	no	14.605	14.439	EPSD;PhosphoSitePlus	COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	Q08999	RBL2	P24941	CDK2	S1080	K1083N	1083	Missense	distal	3	no	17.587	14.316	EPSD;PhosphoSitePlus	COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	Q08999	RBL2	P24941	CDK2	T1097	K1100N	1100	Missense	distal	3	no	15.189	11.919	EPSD;PhosphoSitePlus	COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	Q08999	RBL2	P24941	CDK2	T1097	S1090I	1090	Missense	distal	-7	no	15.189	15.564	EPSD;PhosphoSitePlus	COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	Q08999	RBL2	P24941	CDK2	T1097	I1092M	1092	Missense	distal	-5	no	15.189	15.257	EPSD;PhosphoSitePlus	COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	Q08999	RBL2	P24941	CDK2	T1097	R1093H	1093	Missense	distal	-4	no	15.189	14.828	EPSD;PhosphoSitePlus	COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	Q08999	RBL2	P24941	CDK2	S1112	L1106F	1106	Missense	distal	-6	no	17.304	17.308	EPSD;PhosphoSitePlus	COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	Q08999	RBL2	P24941	CDK2	S1112	P1113S	1113	Missense	proximal	1	no	17.304	6.038	EPSD;PhosphoSitePlus	COSMIC	8.148	Loss
CMGC_CDK_CDK2_CDK2_ST	P10636	MAPT	P24941	CDK2	T69	E62K	62	Missense	distal	-7	no	13.645	13.508	EPSD	COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	P10636	MAPT	P24941	CDK2	T111	I108V	108	Missense	distal	-3	no	13.764	13.887	EPSD	COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	P10636	MAPT	P24941	CDK2	T111	G107R	107	Missense	distal	-4	no	13.764	13.839	EPSD	COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	P10636	MAPT	P24941	CDK2	T173	P175S	175	Missense	proximal	2	no	9.577	9.644	EPSD	COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	P10636	MAPT	P24941	CDK2	T173	A166V	166	Missense	distal	-7	no	9.577	9.432	EPSD	COSMIC;CCLE	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	P10636	MAPT	P24941	CDK2	T173	E176G	176	Missense	distal	3	no	9.577	8.854	EPSD	COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	P10636	MAPT	P24941	CDK2	T173	D177G	177	Missense	distal	4	no	9.577	9.522	EPSD	COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	P10636	MAPT	P24941	CDK2	T173	G172V	172	Missense	proximal	-1	no	9.577	8.485	EPSD	COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	P10636	MAPT	P24941	CDK2	S228	S227N	227	Missense	proximal	-1	no	9.983	10.380	EPSD	COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	P10636	MAPT	P24941	CDK2	S228	S227I	227	Missense	proximal	-1	no	9.983	10.437	EPSD	COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	P10636	MAPT	P24941	CDK2	S228	E226K	226	Missense	proximal	-2	no	9.983	10.584	EPSD	COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	P10636	MAPT	P24941	CDK2	S228	Q230R	230	Missense	proximal	2	no	9.983	10.083	EPSD	COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	P10636	MAPT	P24941	CDK2	S228	P233S	233	Missense	distal	5	no	9.983	9.882	EPSD	COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	P10636	MAPT	P24941	CDK2	S228	D225E	225	Missense	distal	-3	no	9.983	10.093	EPSD	COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	P10636	MAPT	P24941	CDK2	S228	S227G	227	Missense	proximal	-1	no	9.983	11.503	EPSD	COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	P10636	MAPT	P24941	CDK2	S228	S235L	235	Missense	distal	7	no	9.983	10.166	EPSD	COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	P10636	MAPT	P24941	CDK2	S232	S227N	227	Missense	distal	-5	no	15.341	15.405	EPSD	COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	P10636	MAPT	P24941	CDK2	S232	S227I	227	Missense	distal	-5	no	15.341	15.425	EPSD	COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	P10636	MAPT	P24941	CDK2	S232	A237T	237	Missense	distal	5	no	15.341	15.306	EPSD	COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	P10636	MAPT	P24941	CDK2	S232	E226K	226	Missense	distal	-6	no	15.341	15.339	EPSD	COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	P10636	MAPT	P24941	CDK2	S232	Q230R	230	Missense	proximal	-2	no	15.341	14.673	EPSD	COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	P10636	MAPT	P24941	CDK2	S232	S238P	238	Missense	distal	6	no	15.341	15.340	EPSD	COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	P10636	MAPT	P24941	CDK2	S232	P233S	233	Missense	proximal	1	no	15.341	4.076	EPSD	COSMIC	8.148	Loss
CMGC_CDK_CDK2_CDK2_ST	P10636	MAPT	P24941	CDK2	S232	S238F	238	Missense	distal	6	no	15.341	15.322	EPSD	COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	P10636	MAPT	P24941	CDK2	S232	D225E	225	Missense	distal	-7	no	15.341	15.190	EPSD	COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	P10636	MAPT	P24941	CDK2	S232	S227G	227	Missense	distal	-5	no	15.341	15.465	EPSD	COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	P10636	MAPT	P24941	CDK2	S232	S235L	235	Missense	distal	3	no	15.341	14.924	EPSD	COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	P10636	MAPT	P24941	CDK2	S238	A237T	237	Missense	proximal	-1	no	14.454	14.461	EPSD	COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	P10636	MAPT	P24941	CDK2	S238	A240S	240	Missense	proximal	2	no	14.454	14.496	EPSD	COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	P10636	MAPT	P24941	CDK2	S238	D242N	242	Missense	distal	4	no	14.454	14.499	EPSD	COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	P10636	MAPT	P24941	CDK2	S238	R244W	244	Missense	distal	6	no	14.454	14.446	EPSD	COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	P10636	MAPT	P24941	CDK2	S238	S238P	238	Missense	central	0	yes	14.454	0.000	EPSD	COSMIC	8.148	Loss
CMGC_CDK_CDK2_CDK2_ST	P10636	MAPT	P24941	CDK2	S238	P233S	233	Missense	distal	-5	no	14.454	14.409	EPSD	COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	P10636	MAPT	P24941	CDK2	S238	S238F	238	Missense	central	0	yes	14.454	0.000	EPSD	COSMIC	8.148	Loss
CMGC_CDK_CDK2_CDK2_ST	P10636	MAPT	P24941	CDK2	S238	G243D	243	Missense	distal	5	no	14.454	14.501	EPSD	COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	P10636	MAPT	P24941	CDK2	S238	S235L	235	Missense	distal	-3	no	14.454	14.287	EPSD	COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	P10636	MAPT	P24941	CDK2	S388	G385V	385	Missense	distal	-3	no	10.322	10.362	EPSD	COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	P10636	MAPT	P24941	CDK2	S388	T386I	386	Missense	proximal	-2	no	10.322	10.202	EPSD	COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	P10636	MAPT	P24941	CDK2	S388	D389N	389	Missense	proximal	1	no	10.322	-22.046	EPSD	COSMIC;GDSC;CCLE	8.148	Loss
CMGC_CDK_CDK2_CDK2_ST	P10636	MAPT	P24941	CDK2	S411	L410F	410	Missense	proximal	-1	no	12.787	13.753	EPSD	COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	P10636	MAPT	P24941	CDK2	S411	P412S	412	Missense	proximal	1	no	12.787	1.521	EPSD	COSMIC	8.148	Loss
CMGC_CDK_CDK2_CDK2_ST	P10636	MAPT	P24941	CDK2	T416	L410F	410	Missense	distal	-6	no	13.499	13.503	EPSD	COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	P10636	MAPT	P24941	CDK2	T416	P412S	412	Missense	distal	-4	no	13.499	13.853	EPSD	COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	P10636	MAPT	P24941	CDK2	S438	S443Y	443	Missense	distal	5	no	13.556	13.731	EPSD	COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	P10636	MAPT	P24941	CDK2	T470	T466M	466	Missense	distal	-4	no	10.897	9.982	EPSD	COSMIC;GDSC;CCLE	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	P10636	MAPT	P24941	CDK2	T470	K467T	467	Missense	distal	-3	no	10.897	10.898	EPSD	COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	P10636	MAPT	P24941	CDK2	T470	P477L	477	Missense	distal	7	no	10.897	10.928	EPSD	COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	P10636	MAPT	P24941	CDK2	T470	P477S	477	Missense	distal	7	no	10.897	10.745	EPSD	COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	P10636	MAPT	P24941	CDK2	T492	R487K	487	Missense	distal	-5	no	12.497	12.453	EPSD	COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	P10636	MAPT	P24941	CDK2	T492	K491R	491	Missense	proximal	-1	no	12.497	13.168	EPSD	COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	P10636	MAPT	P24941	CDK2	T492	R487G	487	Missense	distal	-5	no	12.497	12.530	EPSD	COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	P10636	MAPT	P24941	CDK2	T492	A495T	495	Missense	distal	3	no	12.497	12.895	EPSD	COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	P10636	MAPT	P24941	CDK2	T492	P493L	493	Missense	proximal	1	no	12.497	2.676	EPSD	COSMIC	8.148	Loss
CMGC_CDK_CDK2_CDK2_ST	P10636	MAPT	P24941	CDK2	T498	K491R	491	Missense	distal	-7	no	12.688	13.079	EPSD	COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	P10636	MAPT	P24941	CDK2	T498	A495T	495	Missense	distal	-3	no	12.688	12.707	EPSD	COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	P10636	MAPT	P24941	CDK2	T498	P493L	493	Missense	distal	-5	no	12.688	12.700	EPSD	COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	P10636	MAPT	P24941	CDK2	S516	G521V	521	Missense	distal	5	no	12.476	12.317	EPSD	COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	P10636	MAPT	P24941	CDK2	S516	G518V	518	Missense	proximal	2	no	12.476	12.481	EPSD	COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	P10636	MAPT	P24941	CDK2	S516	R511C	511	Missense	distal	-5	no	12.476	12.510	EPSD	COSMIC;CCLE	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	P10636	MAPT	P24941	CDK2	S516	G509V	509	Missense	distal	-7	no	12.476	12.171	EPSD	COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	P10636	MAPT	P24941	CDK2	S519	G521V	521	Missense	proximal	2	no	16.829	16.834	EPSD	COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	P10636	MAPT	P24941	CDK2	S519	R526H	526	Missense	distal	7	no	16.829	16.470	EPSD	COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	P10636	MAPT	P24941	CDK2	S519	G518V	518	Missense	proximal	-1	no	16.829	15.737	EPSD	COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	P10636	MAPT	P24941	CDK2	T522	G521V	521	Missense	proximal	-1	no	12.687	11.595	EPSD	COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	P10636	MAPT	P24941	CDK2	T522	R526H	526	Missense	distal	4	no	12.687	12.569	EPSD	COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	P10636	MAPT	P24941	CDK2	T522	G518V	518	Missense	distal	-4	no	12.687	12.956	EPSD	COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	P10636	MAPT	P24941	CDK2	T522	R528S	528	Missense	distal	6	no	12.687	12.704	EPSD	COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	P10636	MAPT	P24941	CDK2	S525	R526H	526	Missense	proximal	1	no	7.046	10.086	EPSD	COSMIC	8.148	Gain
CMGC_CDK_CDK2_CDK2_ST	P10636	MAPT	P24941	CDK2	T529	R526H	526	Missense	distal	-3	no	13.229	13.186	EPSD	COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	P10636	MAPT	P24941	CDK2	T529	R528S	528	Missense	proximal	-1	no	13.229	12.187	EPSD	COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	P10636	MAPT	P24941	CDK2	T529	P530S	530	Missense	proximal	1	no	13.229	1.963	EPSD	COSMIC	8.148	Loss
CMGC_CDK_CDK2_CDK2_ST	P10636	MAPT	P24941	CDK2	T529	P536H	536	Missense	distal	7	no	13.229	13.360	EPSD	COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	P10636	MAPT	P24941	CDK2	T529	P535Q	535	Missense	distal	6	no	13.229	13.235	EPSD	COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	P10636	MAPT	P24941	CDK2	T534	R528S	528	Missense	distal	-6	no	12.632	12.629	EPSD	COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	P10636	MAPT	P24941	CDK2	T534	P530S	530	Missense	distal	-4	no	12.632	12.987	EPSD	COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	P10636	MAPT	P24941	CDK2	T534	P536H	536	Missense	proximal	2	no	12.632	12.710	EPSD	COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	P10636	MAPT	P24941	CDK2	T534	P535Q	535	Missense	proximal	1	no	12.632	4.720	EPSD	COSMIC	8.148	Loss
CMGC_CDK_CDK2_CDK2_ST	P10636	MAPT	P24941	CDK2	T534	E539Q	539	Missense	distal	5	no	12.632	12.513	EPSD	COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	P10636	MAPT	P24941	CDK2	T548	P550S	550	Missense	proximal	2	no	16.054	16.120	EPSD	COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	P10636	MAPT	P24941	CDK2	T548	P553R	553	Missense	distal	5	no	16.054	16.160	EPSD	COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	P10636	MAPT	P24941	CDK2	T548	P553L	553	Missense	distal	5	no	16.054	16.094	EPSD	COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	P10636	MAPT	P24941	CDK2	T548	P549L	549	Missense	proximal	1	no	16.054	6.233	EPSD	COSMIC	8.148	Loss
CMGC_CDK_CDK2_CDK2_ST	P10636	MAPT	P24941	CDK2	T548	S555F	555	Missense	distal	7	no	16.054	16.907	EPSD	COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	P10636	MAPT	P24941	CDK2	T548	P553Q	553	Missense	distal	5	no	16.054	16.014	EPSD	COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	P10636	MAPT	P24941	CDK2	S552	P550S	550	Missense	proximal	-2	no	15.497	14.846	EPSD	COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	P10636	MAPT	P24941	CDK2	S552	R559C	559	Missense	distal	7	no	15.497	15.648	EPSD	COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	P10636	MAPT	P24941	CDK2	S552	P553R	553	Missense	proximal	1	no	15.497	5.698	EPSD	COSMIC	8.148	Loss
CMGC_CDK_CDK2_CDK2_ST	P10636	MAPT	P24941	CDK2	S552	P553L	553	Missense	proximal	1	no	15.497	5.676	EPSD	COSMIC	8.148	Loss
CMGC_CDK_CDK2_CDK2_ST	P10636	MAPT	P24941	CDK2	S552	P549L	549	Missense	distal	-3	no	15.497	15.426	EPSD	COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	P10636	MAPT	P24941	CDK2	S552	S555F	555	Missense	distal	3	no	15.497	15.422	EPSD	COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	P10636	MAPT	P24941	CDK2	S552	P553Q	553	Missense	proximal	1	no	15.497	7.585	EPSD	COSMIC	8.148	Loss
CMGC_CDK_CDK2_CDK2_ST	P10636	MAPT	P24941	CDK2	T703	G706R	706	Missense	distal	3	no	7.169	8.988	EPSD	COSMIC	8.148	Gain
CMGC_CDK_CDK2_CDK2_ST	P10636	MAPT	P24941	CDK2	S713	E708D	708	Missense	distal	-5	no	13.446	13.466	EPSD	COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	P10636	MAPT	P24941	CDK2	S713	G706R	706	Missense	distal	-7	no	13.446	13.465	EPSD	COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	P10636	MAPT	P24941	CDK2	S713	V710M	710	Missense	distal	-3	no	13.446	13.671	EPSD	COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	P10636	MAPT	P24941	CDK2	S713	E708K	708	Missense	distal	-5	no	13.446	13.411	EPSD	COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	P10636	MAPT	P24941	CDK2	S713	V710A	710	Missense	distal	-3	no	13.446	13.244	EPSD	COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	P10636	MAPT	P24941	CDK2	S721	R723W	723	Missense	proximal	2	no	17.338	17.435	EPSD	COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	P10636	MAPT	P24941	CDK2	S721	V728M	728	Missense	distal	7	no	17.338	17.625	EPSD	COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	P10636	MAPT	P24941	CDK2	S721	V728A	728	Missense	distal	7	no	17.338	17.464	EPSD	COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	P10636	MAPT	P24941	CDK2	S739	G732S	732	Missense	distal	-7	no	16.401	15.896	EPSD	COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	P10636	MAPT	P24941	CDK2	S739	D735N	735	Missense	distal	-4	no	16.401	16.012	EPSD	COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	P10636	MAPT	P24941	CDK2	S739	G732C	732	Missense	distal	-7	no	16.401	16.347	EPSD	COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	P10636	MAPT	P24941	CDK2	S739	T744M	744	Missense	distal	5	no	16.401	16.734	EPSD	COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	P10636	MAPT	P24941	CDK2	S739	A743T	743	Missense	distal	4	no	16.401	16.644	EPSD	COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	P10636	MAPT	P24941	CDK2	S752	E748K	748	Missense	distal	-4	no	9.241	8.929	EPSD	COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	Q99728	BARD1	P24941	CDK2	S148	K144N	144	Missense	distal	-4	no	13.307	13.527	EPSD;PhosphoSitePlus	COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	Q99728	BARD1	P24941	CDK2	S148	S151I	151	Missense	distal	3	no	13.307	12.605	EPSD;PhosphoSitePlus	COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	Q99728	BARD1	P24941	CDK2	S148	R150L	150	Missense	proximal	2	no	13.307	13.042	EPSD;PhosphoSitePlus	COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	Q99728	BARD1	P24941	CDK2	S174	A175P	175	Missense	proximal	1	no	-0.446	13.957	EPSD	COSMIC	8.148	Gain
CMGC_CDK_CDK2_CDK2_ST	Q99728	BARD1	P24941	CDK2	S184	P187S	187	Missense	distal	3	no	12.220	12.254	EPSD	COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	Q99728	BARD1	P24941	CDK2	S184	P187L	187	Missense	distal	3	no	12.220	11.837	EPSD	COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	Q99728	BARD1	P24941	CDK2	S184	S186T	186	Missense	proximal	2	no	12.220	11.976	EPSD	COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	Q99728	BARD1	P24941	CDK2	S184	S184F	184	Missense	central	0	yes	12.220	0.000	EPSD	COSMIC	8.148	Loss
CMGC_CDK_CDK2_CDK2_ST	Q99728	BARD1	P24941	CDK2	S184	P187A	187	Missense	distal	3	no	12.220	11.708	EPSD	COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	Q99728	BARD1	P24941	CDK2	S184	A189T	189	Missense	distal	5	no	12.220	12.184	EPSD	COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	Q99728	BARD1	P24941	CDK2	S184	V183L	183	Missense	proximal	-1	no	12.220	12.084	EPSD	COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	Q99728	BARD1	P24941	CDK2	S184	P185L	185	Missense	proximal	1	no	12.220	2.399	EPSD	COSMIC	8.148	Loss
CMGC_CDK_CDK2_CDK2_ST	Q99728	BARD1	P24941	CDK2	S184	S186G	186	Missense	proximal	2	no	12.220	12.271	EPSD	COSMIC;GDSC;CCLE	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	Q99728	BARD1	P24941	CDK2	S186	P187S	187	Missense	proximal	1	no	9.780	-1.486	EPSD	COSMIC	8.148	Loss
CMGC_CDK_CDK2_CDK2_ST	Q99728	BARD1	P24941	CDK2	S186	P187L	187	Missense	proximal	1	no	9.780	-0.041	EPSD	COSMIC	8.148	Loss
CMGC_CDK_CDK2_CDK2_ST	Q99728	BARD1	P24941	CDK2	S186	E193Q	193	Missense	distal	7	no	9.780	9.581	EPSD	COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	Q99728	BARD1	P24941	CDK2	S186	S184F	184	Missense	proximal	-2	no	9.780	9.318	EPSD	COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	Q99728	BARD1	P24941	CDK2	S186	P187A	187	Missense	proximal	1	no	9.780	-4.624	EPSD	COSMIC	8.148	Loss
CMGC_CDK_CDK2_CDK2_ST	Q99728	BARD1	P24941	CDK2	S186	A189T	189	Missense	distal	3	no	9.780	10.178	EPSD	COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	Q99728	BARD1	P24941	CDK2	S186	V183L	183	Missense	distal	-3	no	9.780	9.566	EPSD	COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	Q99728	BARD1	P24941	CDK2	S186	P185L	185	Missense	proximal	-1	no	9.780	9.600	EPSD	COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	Q99728	BARD1	P24941	CDK2	S186	S186G	186	Missense	central	0	yes	9.780	0.000	EPSD	COSMIC;GDSC;CCLE	8.148	Loss
CMGC_CDK_CDK2_CDK2_ST	Q99728	BARD1	P24941	CDK2	S251	P252S	252	Missense	proximal	1	no	15.213	3.948	PhosphoSitePlus;EPSD	COSMIC	8.148	Loss
CMGC_CDK_CDK2_CDK2_ST	Q99728	BARD1	P24941	CDK2	S251	S247F	247	Missense	distal	-4	no	15.213	14.251	PhosphoSitePlus;EPSD	COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	Q99728	BARD1	P24941	CDK2	S251	P246Q	246	Missense	distal	-5	no	15.213	15.214	PhosphoSitePlus;EPSD	COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	Q99728	BARD1	P24941	CDK2	S251	S247L	247	Missense	distal	-4	no	15.213	14.801	PhosphoSitePlus;EPSD	COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	Q99728	BARD1	P24941	CDK2	S288	E287G	287	Missense	proximal	-1	no	14.800	15.063	EPSD;PhosphoSitePlus	COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	Q99728	BARD1	P24941	CDK2	S288	R294S	294	Missense	distal	6	no	14.800	14.817	EPSD;PhosphoSitePlus	COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	Q99728	BARD1	P24941	CDK2	S288	K292N	292	Missense	distal	4	no	14.800	14.378	EPSD;PhosphoSitePlus	COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	Q99728	BARD1	P24941	CDK2	S288	D290H	290	Missense	proximal	2	no	14.800	14.880	EPSD;PhosphoSitePlus	COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	Q99728	BARD1	P24941	CDK2	S288	A283V	283	Missense	distal	-5	no	14.800	14.806	EPSD;PhosphoSitePlus	COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	Q99728	BARD1	P24941	CDK2	S288	L282F	282	Missense	distal	-6	no	14.800	14.804	EPSD;PhosphoSitePlus	COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	Q99728	BARD1	P24941	CDK2	S288	S288C	288	Missense	central	0	yes	14.800	0.000	EPSD;PhosphoSitePlus	COSMIC	8.148	Loss
CMGC_CDK_CDK2_CDK2_ST	Q99728	BARD1	P24941	CDK2	S288	E287A	287	Missense	proximal	-1	no	14.800	13.745	EPSD;PhosphoSitePlus	COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	Q99728	BARD1	P24941	CDK2	S288	P281T	281	Missense	distal	-7	no	14.800	14.797	EPSD;PhosphoSitePlus	COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	Q99728	BARD1	P24941	CDK2	T299	V297A	297	Missense	proximal	-2	no	16.297	16.963	EPSD;PhosphoSitePlus	COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	Q99728	BARD1	P24941	CDK2	T299	V297I	297	Missense	proximal	-2	no	16.297	16.793	EPSD;PhosphoSitePlus	COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	Q99728	BARD1	P24941	CDK2	T299	E301K	301	Missense	proximal	2	no	16.297	16.059	EPSD;PhosphoSitePlus	COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	Q99728	BARD1	P24941	CDK2	T299	V298E	298	Missense	proximal	-1	no	16.297	17.125	EPSD;PhosphoSitePlus	COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	Q99728	BARD1	P24941	CDK2	T299	R294S	294	Missense	distal	-5	no	16.297	16.206	EPSD;PhosphoSitePlus	COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	Q99728	BARD1	P24941	CDK2	T299	K292N	292	Missense	distal	-7	no	16.297	16.263	EPSD;PhosphoSitePlus	COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	Q99728	BARD1	P24941	CDK2	S330	H324N	324	Missense	distal	-6	no	15.952	15.947	EPSD	COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	Q99728	BARD1	P24941	CDK2	S330	P331F	331	Missense	proximal	1	no	15.952	1.141	EPSD	COSMIC	8.148	Loss
CMGC_CDK_CDK2_CDK2_ST	Q99728	BARD1	P24941	CDK2	S330	P331R	331	Missense	proximal	1	no	15.952	6.153	EPSD	COSMIC	8.148	Loss
CMGC_CDK_CDK2_CDK2_ST	Q99728	BARD1	P24941	CDK2	S330	S330I	330	Missense	central	0	yes	15.952	0.000	EPSD	COSMIC	8.148	Loss
CMGC_CDK_CDK2_CDK2_ST	Q99728	BARD1	P24941	CDK2	S330	P331L	331	Missense	proximal	1	no	15.952	6.131	EPSD	COSMIC	8.148	Loss
CMGC_CDK_CDK2_CDK2_ST	Q99728	BARD1	P24941	CDK2	S330	S329F	329	Missense	proximal	-1	no	15.952	17.208	EPSD	COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	Q99728	BARD1	P24941	CDK2	S364	L359S	359	Missense	distal	-5	no	12.963	12.907	EPSD	COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	Q99728	BARD1	P24941	CDK2	S364	S364L	364	Missense	central	0	yes	12.963	0.000	EPSD	COSMIC	8.148	Loss
CMGC_CDK_CDK2_CDK2_ST	Q99728	BARD1	P24941	CDK2	S364	P366L	366	Missense	proximal	2	no	12.963	12.856	EPSD	COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	Q99728	BARD1	P24941	CDK2	S364	P365S	365	Missense	proximal	1	no	12.963	1.697	EPSD	COSMIC	8.148	Loss
CMGC_CDK_CDK2_CDK2_ST	Q99728	BARD1	P24941	CDK2	S391	P392H	392	Missense	proximal	1	no	13.256	6.497	EPSD	COSMIC	8.148	Loss
CMGC_CDK_CDK2_CDK2_ST	Q99728	BARD1	P24941	CDK2	S391	D385N	385	Missense	distal	-6	no	13.256	13.257	EPSD	COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	Q99728	BARD1	P24941	CDK2	S391	P392S	392	Missense	proximal	1	no	13.256	1.990	EPSD	COSMIC	8.148	Loss
CMGC_CDK_CDK2_CDK2_ST	Q99728	BARD1	P24941	CDK2	S391	S389R	389	Missense	proximal	-2	no	13.256	12.671	EPSD	COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	Q99728	BARD1	P24941	CDK2	S391	P392L	392	Missense	proximal	1	no	13.256	3.435	EPSD	COSMIC	8.148	Loss
CMGC_CDK_CDK2_CDK2_ST	Q99728	BARD1	P24941	CDK2	T394	S401N	401	Missense	distal	7	no	13.132	13.191	EPSD	COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	Q99728	BARD1	P24941	CDK2	T394	P392H	392	Missense	proximal	-2	no	13.132	12.122	EPSD	COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	Q99728	BARD1	P24941	CDK2	T394	P392S	392	Missense	proximal	-2	no	13.132	12.481	EPSD	COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	Q99728	BARD1	P24941	CDK2	T394	S389R	389	Missense	distal	-5	no	13.132	13.224	EPSD	COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	Q99728	BARD1	P24941	CDK2	T394	P392L	392	Missense	proximal	-2	no	13.132	12.908	EPSD	COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	Q99728	BARD1	P24941	CDK2	S410	R406L	406	Missense	distal	-4	no	9.833	10.017	EPSD	COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	Q99728	BARD1	P24941	CDK2	S410	M414I	414	Missense	distal	4	no	9.833	10.225	EPSD	COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	Q99728	BARD1	P24941	CDK2	S410	K415R	415	Missense	distal	5	no	9.833	9.993	EPSD	COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	Q99728	BARD1	P24941	CDK2	S410	P411L	411	Missense	proximal	1	no	9.833	0.012	EPSD	COSMIC	8.148	Loss
CMGC_CDK_CDK2_CDK2_ST	Q99728	BARD1	P24941	CDK2	S496	T490P	490	Missense	distal	-6	no	13.404	13.405	EPSD	COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	Q99728	BARD1	P24941	CDK2	S496	T489I	489	Missense	distal	-7	no	13.404	13.601	EPSD	COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	Q99728	BARD1	P24941	CDK2	S496	D500H	500	Missense	distal	4	no	13.404	13.232	EPSD	COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	Q99728	BARD1	P24941	CDK2	S496	G491R	491	Missense	distal	-5	no	13.404	13.372	EPSD	COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	Q99728	BARD1	P24941	CDK2	S496	A502N	502	Missense	distal	6	no	13.404	13.412	EPSD	COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	Q99728	BARD1	P24941	CDK2	S496	T490I	490	Missense	distal	-6	no	13.404	13.407	EPSD	COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	Q99728	BARD1	P24941	CDK2	S496	H499Y	499	Missense	distal	3	no	13.404	11.637	EPSD	COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	Q99728	BARD1	P24941	CDK2	S496	P497L	497	Missense	proximal	1	no	13.404	3.584	EPSD	COSMIC	8.148	Loss
CMGC_CDK_CDK2_CDK2_ST	Q99728	BARD1	P24941	CDK2	S496	S496A	496	Missense	central	0	yes	13.404	0.000	EPSD	COSMIC	8.148	Loss
CMGC_CDK_CDK2_CDK2_ST	Q99728	BARD1	P24941	CDK2	S496	S496F	496	Missense	central	0	yes	13.404	0.000	EPSD	COSMIC	8.148	Loss
CMGC_CDK_CDK2_CDK2_ST	Q99728	BARD1	P24941	CDK2	S555	V559A	559	Missense	distal	4	no	8.657	8.470	EPSD	COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	Q99728	BARD1	P24941	CDK2	S555	S553L	553	Missense	proximal	-2	no	8.657	9.084	EPSD	COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	O43303	CCP110	P24941	CDK2	S170	P171Q	171	Missense	proximal	1	no	11.005	3.094	EPSD;PhosphoSitePlus	COSMIC	8.148	Loss
CMGC_CDK_CDK2_CDK2_ST	O43303	CCP110	P24941	CDK2	S170	D164N	164	Missense	distal	-6	no	11.005	11.006	EPSD;PhosphoSitePlus	COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	O43303	CCP110	P24941	CDK2	T194	S192L	192	Missense	proximal	-2	no	14.853	15.280	EPSD;PhosphoSitePlus	COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	O43303	CCP110	P24941	CDK2	T194	F187V	187	Missense	distal	-7	no	14.853	14.501	EPSD;PhosphoSitePlus	COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	O43303	CCP110	P24941	CDK2	T194	P195T	195	Missense	proximal	1	no	14.853	4.896	EPSD;PhosphoSitePlus	COSMIC	8.148	Loss
CMGC_CDK_CDK2_CDK2_ST	O43303	CCP110	P24941	CDK2	S372	R379C	379	Missense	distal	7	no	15.180	15.331	EPSD;PhosphoSitePlus	COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	O43303	CCP110	P24941	CDK2	S400	E405K	405	Missense	distal	5	no	12.307	12.174	EPSD;PhosphoSitePlus	COSMIC;GDSC;CCLE	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	O43303	CCP110	P24941	CDK2	T566	P567S	567	Missense	proximal	1	no	12.381	1.116	EPSD;PhosphoSitePlus	COSMIC	8.148	Loss
CMGC_CDK_CDK2_CDK2_ST	O43303	CCP110	P24941	CDK2	S625	K632E	632	Missense	distal	7	no	7.940	8.270	EPSD	COSMIC	8.148	Gain
CMGC_CDK_CDK2_CDK2_ST	O43303	CCP110	P24941	CDK2	S788	A783V	783	Missense	distal	-5	no	8.763	8.769	EPSD	COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	O43303	CCP110	P24941	CDK2	S906	P907S	907	Missense	proximal	1	no	14.700	3.434	EPSD	COSMIC	8.148	Loss
CMGC_CDK_CDK2_CDK2_ST	O43303	CCP110	P24941	CDK2	S995	A999T	999	Missense	distal	4	no	7.906	8.149	EPSD	COSMIC	8.148	Gain
CMGC_CDK_CDK2_CDK2_ST	Q15648	MED1	P24941	CDK2	T64	L65S	65	Missense	proximal	1	no	10.470	9.025	EPSD	COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	Q15648	MED1	P24941	CDK2	T64	T64A	64	Missense	central	0	yes	10.470	0.000	EPSD	COSMIC	8.148	Loss
CMGC_CDK_CDK2_CDK2_ST	Q15648	MED1	P24941	CDK2	T212	L211R	211	Missense	proximal	-1	no	12.211	12.961	EPSD	COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	Q15648	MED1	P24941	CDK2	S238	N245S	245	Missense	distal	7	no	15.247	15.189	EPSD	COSMIC;GDSC;CCLE	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	Q15648	MED1	P24941	CDK2	S434	G436V	436	Missense	proximal	2	no	11.706	11.711	EPSD	COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	Q15648	MED1	P24941	CDK2	S448	R449H	449	Missense	proximal	1	no	6.285	9.325	EPSD	COSMIC	8.148	Gain
CMGC_CDK_CDK2_CDK2_ST	Q15648	MED1	P24941	CDK2	T522	D521N	521	Missense	proximal	-1	no	14.849	14.020	EPSD	COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	Q15648	MED1	P24941	CDK2	S545	P542Q	542	Missense	distal	-3	no	10.255	10.314	EPSD	COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	Q15648	MED1	P24941	CDK2	S558	T564I	564	Missense	distal	6	no	8.350	8.342	EPSD	COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	Q15648	MED1	P24941	CDK2	S558	P563T	563	Missense	distal	5	no	8.350	8.324	EPSD	COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	Q15648	MED1	P24941	CDK2	T562	T564I	564	Missense	proximal	2	no	13.317	13.471	EPSD	COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	Q15648	MED1	P24941	CDK2	T562	P568Q	568	Missense	distal	6	no	13.317	13.322	EPSD	COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	Q15648	MED1	P24941	CDK2	T562	P568S	568	Missense	distal	6	no	13.317	13.318	EPSD	COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	Q15648	MED1	P24941	CDK2	T562	P563T	563	Missense	proximal	1	no	13.317	3.359	EPSD	COSMIC	8.148	Loss
CMGC_CDK_CDK2_CDK2_ST	Q15648	MED1	P24941	CDK2	S621	T623P	623	Missense	proximal	2	no	13.041	13.218	EPSD	COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	Q15648	MED1	P24941	CDK2	S621	G614E	614	Missense	distal	-7	no	13.041	12.807	EPSD	COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	Q15648	MED1	P24941	CDK2	T623	T623P	623	Missense	central	0	yes	13.117	0.000	EPSD	COSMIC	8.148	Loss
CMGC_CDK_CDK2_CDK2_ST	Q15648	MED1	P24941	CDK2	T628	T623P	623	Missense	distal	-5	no	13.507	13.508	EPSD	COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	Q15648	MED1	P24941	CDK2	S675	S673F	673	Missense	proximal	-2	no	14.437	13.976	EPSD	COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	Q15648	MED1	P24941	CDK2	T735	H737Y	737	Missense	proximal	2	no	13.988	13.968	EPSD	COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	Q15648	MED1	P24941	CDK2	T739	H737Y	737	Missense	proximal	-2	no	12.522	12.968	EPSD	COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	Q15648	MED1	P24941	CDK2	T805	D798N	798	Missense	distal	-7	no	17.602	17.280	EPSD	COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	Q15648	MED1	P24941	CDK2	T805	S810C	810	Missense	distal	5	no	17.602	17.937	EPSD	COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	Q15648	MED1	P24941	CDK2	S848	L841V	841	Missense	distal	-7	no	16.825	16.839	EPSD	COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	Q15648	MED1	P24941	CDK2	S848	L841F	841	Missense	distal	-7	no	16.825	17.191	EPSD	COSMIC;GDSC;CCLE	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	Q15648	MED1	P24941	CDK2	T998	G993E	993	Missense	distal	-5	no	11.879	11.837	EPSD	COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	Q15648	MED1	P24941	CDK2	T998	T998I	998	Missense	central	0	yes	11.879	0.000	EPSD	COSMIC	8.148	Loss
CMGC_CDK_CDK2_CDK2_ST	Q15648	MED1	P24941	CDK2	T998	S1000F	1000	Missense	proximal	2	no	11.879	12.064	EPSD	COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	Q15648	MED1	P24941	CDK2	T1017	P1022Q	1022	Missense	distal	5	no	8.800	8.760	EPSD	COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	Q15648	MED1	P24941	CDK2	T1017	R1012W	1012	Missense	distal	-5	no	8.800	8.887	EPSD	COSMIC;GDSC;CCLE	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	Q15648	MED1	P24941	CDK2	S1021	P1022Q	1022	Missense	proximal	1	no	12.748	4.836	EPSD	COSMIC	8.148	Loss
CMGC_CDK_CDK2_CDK2_ST	Q15648	MED1	P24941	CDK2	S1023	P1022Q	1022	Missense	proximal	-1	no	8.771	8.463	EPSD	COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	Q15648	MED1	P24941	CDK2	S1042	G1044C	1044	Missense	proximal	2	no	12.277	12.306	EPSD	COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	Q15648	MED1	P24941	CDK2	S1042	S1042L	1042	Missense	central	0	yes	12.277	0.000	EPSD	COSMIC	8.148	Loss
CMGC_CDK_CDK2_CDK2_ST	Q15648	MED1	P24941	CDK2	T1051	G1044C	1044	Missense	distal	-7	no	11.862	11.808	EPSD	COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	Q15648	MED1	P24941	CDK2	T1051	P1052F	1052	Missense	proximal	1	no	11.862	-2.948	EPSD	COSMIC	8.148	Loss
CMGC_CDK_CDK2_CDK2_ST	Q15648	MED1	P24941	CDK2	T1051	P1052S	1052	Missense	proximal	1	no	11.862	0.596	EPSD	COSMIC	8.148	Loss
CMGC_CDK_CDK2_CDK2_ST	Q15648	MED1	P24941	CDK2	T1057	P1052F	1052	Missense	distal	-5	no	10.178	10.250	EPSD	COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	Q15648	MED1	P24941	CDK2	T1057	P1052S	1052	Missense	distal	-5	no	10.178	10.133	EPSD	COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	Q15648	MED1	P24941	CDK2	S1141	S1137F	1137	Missense	distal	-4	no	9.201	8.239	EPSD	COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	Q15648	MED1	P24941	CDK2	S1156	P1157A	1157	Missense	proximal	1	no	12.453	-1.950	EPSD	COSMIC	8.148	Loss
CMGC_CDK_CDK2_CDK2_ST	Q15648	MED1	P24941	CDK2	S1207	G1214E	1214	Missense	distal	7	no	17.974	17.348	PhosphoSitePlus;EPSD	COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	Q15648	MED1	P24941	CDK2	T1215	G1214E	1214	Missense	proximal	-1	no	16.403	16.139	EPSD;PhosphoSitePlus	COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	Q15648	MED1	P24941	CDK2	T1215	P1217L	1217	Missense	proximal	2	no	16.403	16.296	EPSD;PhosphoSitePlus	COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	Q15648	MED1	P24941	CDK2	S1223	G1228D	1228	Missense	distal	5	no	14.926	14.973	EPSD	COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	Q15648	MED1	P24941	CDK2	S1229	S1232F	1232	Missense	distal	3	no	8.322	8.247	EPSD	COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	Q15648	MED1	P24941	CDK2	S1229	G1228D	1228	Missense	proximal	-1	no	8.322	8.029	EPSD	COSMIC	8.148	Loss
CMGC_CDK_CDK2_CDK2_ST	Q15648	MED1	P24941	CDK2	S1232	G1228D	1228	Missense	distal	-4	no	7.785	8.630	EPSD	COSMIC	8.148	Gain
CMGC_CDK_CDK2_CDK2_ST	Q15648	MED1	P24941	CDK2	T1259	P1260S	1260	Missense	proximal	1	no	11.659	0.393	EPSD	COSMIC	8.148	Loss
CMGC_CDK_CDK2_CDK2_ST	Q15648	MED1	P24941	CDK2	S1294	S1290Y	1290	Missense	distal	-4	no	16.915	17.026	EPSD	COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	Q15648	MED1	P24941	CDK2	S1379	S1374P	1374	Missense	distal	-5	no	9.203	9.248	EPSD	COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	Q15648	MED1	P24941	CDK2	S1379	N1383I	1383	Missense	distal	4	no	9.203	9.195	EPSD	COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	Q15648	MED1	P24941	CDK2	S1379	S1386T	1386	Missense	distal	7	no	9.203	9.051	EPSD	COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	Q15648	MED1	P24941	CDK2	S1379	S1374F	1374	Missense	distal	-5	no	9.203	9.320	EPSD	COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	Q15648	MED1	P24941	CDK2	S1439	R1445C	1445	Missense	distal	6	no	9.100	9.103	EPSD	COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	Q15648	MED1	P24941	CDK2	T1440	R1445C	1445	Missense	distal	5	no	13.335	13.462	EPSD	COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	Q15648	MED1	P24941	CDK2	S1447	R1445C	1445	Missense	proximal	-2	no	13.552	13.726	EPSD	COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	Q15648	MED1	P24941	CDK2	S1449	R1445C	1445	Missense	distal	-4	no	9.152	8.644	EPSD	COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	Q15648	MED1	P24941	CDK2	S1453	P1458S	1458	Missense	distal	5	no	14.352	14.251	EPSD	COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	Q15648	MED1	P24941	CDK2	T1457	P1458S	1458	Missense	proximal	1	no	12.822	1.557	EPSD	COSMIC	8.148	Loss
CMGC_CDK_CDK2_CDK2_ST	Q15648	MED1	P24941	CDK2	S1479	E1473D	1473	Missense	distal	-6	no	14.029	14.025	EPSD	COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	Q15648	MED1	P24941	CDK2	S1479	S1479N	1479	Missense	central	0	yes	14.029	0.000	EPSD	COSMIC	8.148	Loss
CMGC_CDK_CDK2_CDK2_ST	Q15648	MED1	P24941	CDK2	S1561	P1562S	1562	Missense	proximal	1	no	15.660	4.394	EPSD	COSMIC	8.148	Loss
CMGC_CDK_CDK2_CDK2_ST	P62324	BTG1	P24941	CDK2	S159	E152A	152	Missense	distal	-7	no	16.830	16.904	PhosphoSitePlus	COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	P62324	BTG1	P24941	CDK2	S159	T158S	158	Missense	proximal	-1	no	16.830	16.622	PhosphoSitePlus	COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	P19338	NCL	P24941	CDK2	S67	V65A	65	Missense	proximal	-2	no	16.712	17.378	EPSD	COSMIC;CCLE	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	P19338	NCL	P24941	CDK2	S67	V66I	66	Missense	proximal	-1	no	16.712	16.738	EPSD	COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	P19338	NCL	P24941	CDK2	T92	V98I	98	Missense	distal	6	no	15.307	15.308	EPSD	COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	P19338	NCL	P24941	CDK2	T92	P93H	93	Missense	proximal	1	no	15.307	8.548	EPSD	COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	P19338	NCL	P24941	CDK2	T99	V98I	98	Missense	proximal	-1	no	15.448	15.474	EPSD	COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	P19338	NCL	P24941	CDK2	T99	P93H	93	Missense	distal	-6	no	15.448	15.451	EPSD	COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	P19338	NCL	P24941	CDK2	T113	V119A	119	Missense	distal	6	no	14.880	14.877	EPSD	COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	P19338	NCL	P24941	CDK2	T121	V119A	119	Missense	proximal	-2	no	15.552	16.218	PhosphoSitePlus;EPSD	COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	P19338	NCL	P24941	CDK2	T121	P122L	122	Missense	proximal	1	no	15.552	5.731	PhosphoSitePlus;EPSD	COSMIC	8.148	Loss
CMGC_CDK_CDK2_CDK2_ST	P19338	NCL	P24941	CDK2	S145	D150H	150	Missense	distal	5	no	9.344	9.249	EPSD	COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	P19338	NCL	P24941	CDK2	S145	E143K	143	Missense	proximal	-2	no	9.344	9.945	EPSD	COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	P19338	NCL	P24941	CDK2	S184	A178E	178	Missense	distal	-6	no	9.836	9.840	EPSD	COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	P19338	NCL	P24941	CDK2	S184	E190K	190	Missense	distal	6	no	9.836	9.848	EPSD	COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	P19338	NCL	P24941	CDK2	S482	T480A	480	Missense	proximal	-2	no	10.835	10.885	EPSD	COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	P19338	NCL	P24941	CDK2	T606	R604W	604	Missense	proximal	-2	no	8.433	7.934	EPSD	COSMIC	8.148	Loss
CMGC_CDK_CDK2_CDK2_ST	P13639	EEF2	P24941	CDK2	S279	S274C	274	Missense	distal	-5	no	13.431	13.556	EPSD	COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	P13639	EEF2	P24941	CDK2	S325	E326K	326	Missense	proximal	1	no	9.540	1.056	EPSD	COSMIC	8.148	Loss
CMGC_CDK_CDK2_CDK2_ST	P13639	EEF2	P24941	CDK2	S325	D324H	324	Missense	proximal	-1	no	9.540	8.903	EPSD	COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	P13639	EEF2	P24941	CDK2	S502	V501I	501	Missense	proximal	-1	no	16.016	16.042	EPSD	COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	P13639	EEF2	P24941	CDK2	S502	A508V	508	Missense	distal	6	no	16.016	16.019	EPSD	COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	P13639	EEF2	P24941	CDK2	S595	H599R	599	Missense	distal	4	no	16.187	16.305	EPSD;PhosphoSitePlus	COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	Q9NYV6	RRN3	P24941	CDK2	T623	P624L	624	Missense	proximal	1	no	14.114	4.293	EPSD	COSMIC	8.148	Loss
CMGC_CDK_CDK2_CDK2_ST	Q9NYV6	RRN3	P24941	CDK2	T623	N616S	616	Missense	distal	-7	no	14.114	14.016	EPSD	COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	Q9NYV6	RRN3	P24941	CDK2	T623	T629M	629	Missense	distal	6	no	14.114	14.088	EPSD	COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	Q9NYV6	RRN3	P24941	CDK2	T623	T618I	618	Missense	distal	-5	no	14.114	14.154	EPSD	COSMIC;CCLE	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	Q9NYV6	RRN3	P24941	CDK2	T629	P624L	624	Missense	distal	-5	no	10.139	10.151	EPSD	COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	Q9NYV6	RRN3	P24941	CDK2	T629	T629M	629	Missense	central	0	yes	10.139	0.000	EPSD	COSMIC	8.148	Loss
CMGC_CDK_CDK2_CDK2_ST	Q9NYV6	RRN3	P24941	CDK2	S633	T629M	629	Missense	distal	-4	no	14.473	13.558	EPSD	COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	Q9NYV6	RRN3	P24941	CDK2	S649	P650S	650	Missense	proximal	1	no	10.961	-0.305	EPSD	COSMIC	8.148	Loss
CMGC_CDK_CDK2_CDK2_ST	Q9NYV6	RRN3	P24941	CDK2	S649	P650L	650	Missense	proximal	1	no	10.961	1.140	EPSD	COSMIC	8.148	Loss
CMGC_CDK_CDK2_CDK2_ST	Q9NYV6	RRN3	P24941	CDK2	S649	P648H	648	Missense	proximal	-1	no	10.961	11.080	EPSD	COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	Q9H211	CDT1	P24941	CDK2	S45	T44P	44	Missense	proximal	-1	no	10.206	10.469	EPSD	COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	Q9H211	CDT1	P24941	CDK2	S79	T82I	82	Missense	distal	3	no	12.445	11.891	EPSD	COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	Q9H211	CDT1	P24941	CDK2	T82	P89T	89	Missense	distal	7	no	13.985	13.681	EPSD	COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	Q9H211	CDT1	P24941	CDK2	T82	T82I	82	Missense	central	0	yes	13.985	0.000	EPSD	COSMIC	8.148	Loss
CMGC_CDK_CDK2_CDK2_ST	Q9H211	CDT1	P24941	CDK2	S93	P89T	89	Missense	distal	-4	no	13.057	13.224	EPSD	COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	Q9H211	CDT1	P24941	CDK2	S391	A388V	388	Missense	distal	-3	no	13.572	13.774	EPSD	COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	Q9H211	CDT1	P24941	CDK2	S391	A388G	388	Missense	distal	-3	no	13.572	13.734	EPSD	COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	Q9H211	CDT1	P24941	CDK2	S394	A388V	388	Missense	distal	-6	no	15.927	15.930	EPSD	COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	Q9H211	CDT1	P24941	CDK2	S394	P400S	400	Missense	distal	6	no	15.927	15.928	EPSD	COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	Q9H211	CDT1	P24941	CDK2	S394	A388G	388	Missense	distal	-6	no	15.927	15.930	EPSD	COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	Q9H211	CDT1	P24941	CDK2	T402	P408H	408	Missense	distal	6	no	14.160	14.155	EPSD	COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	Q9H211	CDT1	P24941	CDK2	T402	P400S	400	Missense	proximal	-2	no	14.160	13.509	EPSD	COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	Q9H211	CDT1	P24941	CDK2	T402	P403T	403	Missense	proximal	1	no	14.160	4.203	EPSD	COSMIC	8.148	Loss
CMGC_CDK_CDK2_CDK2_ST	Q9H211	CDT1	P24941	CDK2	T402	P407S	407	Missense	distal	5	no	14.160	14.059	EPSD	COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	Q9H211	CDT1	P24941	CDK2	T402	T402I	402	Missense	central	0	yes	14.160	0.000	EPSD	COSMIC	8.148	Loss
CMGC_CDK_CDK2_CDK2_ST	Q9H211	CDT1	P24941	CDK2	T406	P408H	408	Missense	proximal	2	no	12.369	12.446	EPSD	COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	Q9H211	CDT1	P24941	CDK2	T406	P400S	400	Missense	distal	-6	no	12.369	12.368	EPSD	COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	Q9H211	CDT1	P24941	CDK2	T406	P403T	403	Missense	distal	-3	no	12.369	12.329	EPSD	COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	Q9H211	CDT1	P24941	CDK2	T406	P407S	407	Missense	proximal	1	no	12.369	1.103	EPSD	COSMIC	8.148	Loss
CMGC_CDK_CDK2_CDK2_ST	Q9H211	CDT1	P24941	CDK2	T406	T402I	402	Missense	distal	-4	no	12.369	12.051	EPSD	COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	Q9H211	CDT1	P24941	CDK2	S411	P408H	408	Missense	distal	-3	no	12.954	13.100	EPSD	COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	Q9H211	CDT1	P24941	CDK2	S411	P407S	407	Missense	distal	-4	no	12.954	13.308	EPSD	COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	Q9H211	CDT1	P24941	CDK2	S491	H498Y	498	Missense	distal	7	no	13.349	13.487	EPSD	COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	P25205	MCM3	P24941	CDK2	S112	R114L	114	Missense	proximal	2	no	14.449	14.183	EPSD	COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	P25205	MCM3	P24941	CDK2	S112	G107S	107	Missense	distal	-5	no	14.449	14.325	EPSD	COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	P25205	MCM3	P24941	CDK2	S112	G107D	107	Missense	distal	-5	no	14.449	14.427	EPSD	COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	P25205	MCM3	P24941	CDK2	S112	V111I	111	Missense	proximal	-1	no	14.449	14.475	EPSD	COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	P25205	MCM3	P24941	CDK2	S112	R114Q	114	Missense	proximal	2	no	14.449	14.349	EPSD	COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	P25205	MCM3	P24941	CDK2	S333	R336C	336	Missense	distal	3	no	8.718	2.354	EPSD	COSMIC	8.148	Loss
CMGC_CDK_CDK2_CDK2_ST	P25205	MCM3	P24941	CDK2	S333	L329I	329	Missense	distal	-4	no	8.718	8.626	EPSD	COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	P25205	MCM3	P24941	CDK2	S333	E326K	326	Missense	distal	-7	no	8.718	8.581	EPSD	COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	P25205	MCM3	P24941	CDK2	S333	E330V	330	Missense	distal	-3	no	8.718	8.687	EPSD	COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	P25205	MCM3	P24941	CDK2	S333	R327Q	327	Missense	distal	-6	no	8.718	8.719	EPSD	COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	P25205	MCM3	P24941	CDK2	S333	N340K	340	Missense	distal	7	no	8.718	8.525	EPSD	COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	P25205	MCM3	P24941	CDK2	T464	M466T	466	Missense	proximal	2	no	15.123	14.735	EPSD	COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	P25205	MCM3	P24941	CDK2	T464	G457S	457	Missense	distal	-7	no	15.123	14.619	EPSD	COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	P25205	MCM3	P24941	CDK2	T464	G470W	470	Missense	distal	6	no	15.123	15.111	EPSD	COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	P25205	MCM3	P24941	CDK2	T529	D530H	530	Missense	proximal	1	no	7.341	8.826	EPSD	COSMIC	8.148	Gain
CMGC_CDK_CDK2_CDK2_ST	P25205	MCM3	P24941	CDK2	S611	P612S	612	Missense	proximal	1	no	13.274	2.008	EPSD	COSMIC	8.148	Loss
CMGC_CDK_CDK2_CDK2_ST	P25205	MCM3	P24941	CDK2	S611	P612A	612	Missense	proximal	1	no	13.274	-1.129	EPSD	COSMIC	8.148	Loss
CMGC_CDK_CDK2_CDK2_ST	P25205	MCM3	P24941	CDK2	S611	R616Q	616	Missense	distal	5	no	13.274	13.128	EPSD	COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	P25205	MCM3	P24941	CDK2	S611	T617A	617	Missense	distal	6	no	13.274	13.262	EPSD	COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	P25205	MCM3	P24941	CDK2	S611	A608T	608	Missense	distal	-3	no	13.274	13.293	EPSD	COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	P25205	MCM3	P24941	CDK2	T722	A726T	726	Missense	distal	4	no	14.925	15.168	PhosphoSitePlus	COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	P25205	MCM3	P24941	CDK2	T722	D727E	727	Missense	distal	5	no	14.925	14.831	PhosphoSitePlus	COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	P25205	MCM3	P24941	CDK2	T722	P718L	718	Missense	distal	-4	no	14.925	14.867	PhosphoSitePlus	COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	P25205	MCM3	P24941	CDK2	S728	E730K	730	Missense	proximal	2	no	8.690	8.452	EPSD	COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	P25205	MCM3	P24941	CDK2	S728	A726T	726	Missense	proximal	-2	no	8.690	8.641	EPSD	COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	P25205	MCM3	P24941	CDK2	S728	D727E	727	Missense	proximal	-1	no	8.690	8.720	EPSD	COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	P25205	MCM3	P24941	CDK2	S734	E741D	741	Missense	distal	7	no	7.988	8.630	EPSD	COSMIC	8.148	Gain
CMGC_CDK_CDK2_CDK2_ST	O75179	ANKRD17	P24941	CDK2	S156	A159V	159	Missense	distal	3	no	8.165	9.285	EPSD	COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	O75179	ANKRD17	P24941	CDK2	S156	G157D	157	Missense	proximal	1	no	8.165	7.233	EPSD	COSMIC	8.148	Loss
CMGC_CDK_CDK2_CDK2_ST	O75179	ANKRD17	P24941	CDK2	T227	A228P	228	Missense	proximal	1	no	-2.951	11.452	EPSD	COSMIC	8.148	Gain
CMGC_CDK_CDK2_CDK2_ST	O75179	ANKRD17	P24941	CDK2	T735	L734V	734	Missense	proximal	-1	no	11.447	11.583	EPSD	COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	O75179	ANKRD17	P24941	CDK2	S792	S785N	785	Missense	distal	-7	no	8.474	8.572	EPSD	COSMIC;GDSC;CCLE	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	O75179	ANKRD17	P24941	CDK2	S792	D794V	794	Missense	proximal	2	no	8.474	8.599	EPSD	COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	O75179	ANKRD17	P24941	CDK2	S792	S792N	792	Missense	central	0	yes	8.474	0.000	EPSD	COSMIC	8.148	Loss
CMGC_CDK_CDK2_CDK2_ST	O75179	ANKRD17	P24941	CDK2	S792	Y798H	798	Missense	distal	6	no	8.474	8.476	EPSD	COSMIC;GDSC;CCLE	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	O75179	ANKRD17	P24941	CDK2	S803	Y798H	798	Missense	distal	-5	no	11.099	11.122	EPSD	COSMIC;GDSC;CCLE	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	O75179	ANKRD17	P24941	CDK2	S803	Q802E	802	Missense	proximal	-1	no	11.099	12.192	EPSD	COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	O75179	ANKRD17	P24941	CDK2	T913	L912P	912	Missense	proximal	-1	no	12.811	12.991	EPSD	COSMIC;GDSC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	O75179	ANKRD17	P24941	CDK2	T913	C906Y	906	Missense	distal	-7	no	12.811	12.666	EPSD	COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	O75179	ANKRD17	P24941	CDK2	T913	Q920H	920	Missense	distal	7	no	12.811	13.097	EPSD	COSMIC;CCLE	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	O75179	ANKRD17	P24941	CDK2	T913	Q920K	920	Missense	distal	7	no	12.811	12.679	EPSD	COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	O75179	ANKRD17	P24941	CDK2	T1213	G1218C	1218	Missense	distal	5	no	9.930	10.037	EPSD	COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	O75179	ANKRD17	P24941	CDK2	T1213	E1208K	1208	Missense	distal	-5	no	9.930	9.896	EPSD	COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	O75179	ANKRD17	P24941	CDK2	S1220	M1227V	1227	Missense	distal	7	no	13.395	13.108	EPSD	COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	O75179	ANKRD17	P24941	CDK2	S1220	G1218C	1218	Missense	proximal	-2	no	13.395	13.076	EPSD	COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	O75179	ANKRD17	P24941	CDK2	S1220	A1225T	1225	Missense	distal	5	no	13.395	13.359	EPSD	COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	O75179	ANKRD17	P24941	CDK2	T1287	A1293S	1293	Missense	distal	6	no	13.356	13.362	EPSD	COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	O75179	ANKRD17	P24941	CDK2	T1287	A1282P	1282	Missense	distal	-5	no	13.356	13.331	EPSD	COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	O75179	ANKRD17	P24941	CDK2	T1577	K1573R	1573	Missense	distal	-4	no	12.062	11.900	EPSD	COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	O75179	ANKRD17	P24941	CDK2	T1577	K1575E	1575	Missense	proximal	-2	no	12.062	11.461	EPSD	COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	O75179	ANKRD17	P24941	CDK2	T1577	R1572S	1572	Missense	distal	-5	no	12.062	11.971	EPSD	COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	O75179	ANKRD17	P24941	CDK2	S1609	G1612R	1612	Missense	distal	3	no	6.867	8.686	EPSD	COSMIC	8.148	Gain
CMGC_CDK_CDK2_CDK2_ST	O75179	ANKRD17	P24941	CDK2	S1639	S1635I	1635	Missense	distal	-4	no	11.890	11.385	EPSD	COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	O75179	ANKRD17	P24941	CDK2	S1696	S1699C	1699	Missense	distal	3	no	12.818	8.139	EPSD	COSMIC	8.148	Loss
CMGC_CDK_CDK2_CDK2_ST	O75179	ANKRD17	P24941	CDK2	S1696	P1701L	1701	Missense	distal	5	no	12.818	12.858	EPSD	COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	O75179	ANKRD17	P24941	CDK2	S1696	P1701S	1701	Missense	distal	5	no	12.818	12.718	EPSD	COSMIC;CCLE	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	O75179	ANKRD17	P24941	CDK2	S1700	S1699C	1699	Missense	proximal	-1	no	12.430	12.774	EPSD	COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	O75179	ANKRD17	P24941	CDK2	S1700	V1707I	1707	Missense	distal	7	no	12.430	12.228	EPSD	COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	O75179	ANKRD17	P24941	CDK2	S1700	T1706R	1706	Missense	distal	6	no	12.430	12.406	EPSD	COSMIC;GDSC;CCLE	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	O75179	ANKRD17	P24941	CDK2	S1700	P1701L	1701	Missense	proximal	1	no	12.430	2.609	EPSD	COSMIC	8.148	Loss
CMGC_CDK_CDK2_CDK2_ST	O75179	ANKRD17	P24941	CDK2	S1700	P1701S	1701	Missense	proximal	1	no	12.430	1.164	EPSD	COSMIC;CCLE	8.148	Loss
CMGC_CDK_CDK2_CDK2_ST	O75179	ANKRD17	P24941	CDK2	S1709	R1712L	1712	Missense	distal	3	no	15.165	13.063	EPSD	COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	O75179	ANKRD17	P24941	CDK2	S1709	V1707I	1707	Missense	proximal	-2	no	15.165	15.660	EPSD	COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	O75179	ANKRD17	P24941	CDK2	S1709	T1706R	1706	Missense	distal	-3	no	15.165	15.393	EPSD	COSMIC;GDSC;CCLE	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	O75179	ANKRD17	P24941	CDK2	S1933	P1928L	1928	Missense	distal	-5	no	13.630	13.642	EPSD	COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	O75179	ANKRD17	P24941	CDK2	S1933	P1926S	1926	Missense	distal	-7	no	13.630	13.450	EPSD	COSMIC;GDSC;CCLE	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	O75179	ANKRD17	P24941	CDK2	S1933	P1931L	1931	Missense	proximal	-2	no	13.630	13.406	EPSD	COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	O75179	ANKRD17	P24941	CDK2	S1940	V1946A	1946	Missense	distal	6	no	11.413	11.411	EPSD	COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	O75179	ANKRD17	P24941	CDK2	S1991	S1984I	1984	Missense	distal	-7	no	12.162	12.536	EPSD	COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	O75179	ANKRD17	P24941	CDK2	S1991	Q1997H	1997	Missense	distal	6	no	12.162	12.151	EPSD	COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	O75179	ANKRD17	P24941	CDK2	S1991	P1992S	1992	Missense	proximal	1	no	12.162	0.896	EPSD	COSMIC	8.148	Loss
CMGC_CDK_CDK2_CDK2_ST	O75179	ANKRD17	P24941	CDK2	S1991	S1988N	1988	Missense	distal	-3	no	12.162	12.087	EPSD	COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	O75179	ANKRD17	P24941	CDK2	S1991	P1989L	1989	Missense	proximal	-2	no	12.162	11.938	EPSD	COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	O75179	ANKRD17	P24941	CDK2	S2042	Y2038F	2038	Missense	distal	-4	no	13.105	12.032	EPSD;PhosphoSitePlus	COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	O75179	ANKRD17	P24941	CDK2	S2042	S2041L	2041	Missense	proximal	-1	no	13.105	13.397	EPSD;PhosphoSitePlus	COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	O75179	ANKRD17	P24941	CDK2	S2042	P2049Q	2049	Missense	distal	7	no	13.105	12.951	EPSD;PhosphoSitePlus	COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	O75179	ANKRD17	P24941	CDK2	S2045	Y2038F	2038	Missense	distal	-7	no	14.123	14.368	EPSD;PhosphoSitePlus	COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	O75179	ANKRD17	P24941	CDK2	S2045	S2041L	2041	Missense	distal	-4	no	14.123	13.710	EPSD;PhosphoSitePlus	COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	O75179	ANKRD17	P24941	CDK2	S2045	P2049Q	2049	Missense	distal	4	no	14.123	14.184	EPSD;PhosphoSitePlus	COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	O75179	ANKRD17	P24941	CDK2	S2047	S2041L	2041	Missense	distal	-6	no	12.665	12.666	EPSD	COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	O75179	ANKRD17	P24941	CDK2	S2047	P2049Q	2049	Missense	proximal	2	no	12.665	12.724	EPSD	COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	O75179	ANKRD17	P24941	CDK2	S2059	D2062Y	2062	Missense	distal	3	no	9.089	10.157	EPSD	COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	O75179	ANKRD17	P24941	CDK2	S2059	S2059I	2059	Missense	central	0	yes	9.089	0.000	EPSD	COSMIC;GDSC;CCLE	8.148	Loss
CMGC_CDK_CDK2_CDK2_ST	O75179	ANKRD17	P24941	CDK2	S2067	D2062Y	2062	Missense	distal	-5	no	13.957	13.924	EPSD	COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	O75179	ANKRD17	P24941	CDK2	S2067	A2072S	2072	Missense	distal	5	no	13.957	13.846	EPSD	COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	O75179	ANKRD17	P24941	CDK2	S2067	P2068L	2068	Missense	proximal	1	no	13.957	4.137	EPSD	COSMIC	8.148	Loss
CMGC_CDK_CDK2_CDK2_ST	O75179	ANKRD17	P24941	CDK2	S2067	S2067G	2067	Missense	central	0	yes	13.957	0.000	EPSD	COSMIC	8.148	Loss
CMGC_CDK_CDK2_CDK2_ST	O75179	ANKRD17	P24941	CDK2	S2081	V2084L	2084	Missense	distal	3	no	14.526	13.534	EPSD	COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	O75179	ANKRD17	P24941	CDK2	S2081	S2075C	2075	Missense	distal	-6	no	14.526	14.532	EPSD	COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	O75179	ANKRD17	P24941	CDK2	S2081	T2087A	2087	Missense	distal	6	no	14.526	14.514	EPSD	COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	O75179	ANKRD17	P24941	CDK2	T2279	Q2277H	2277	Missense	proximal	-2	no	10.431	9.988	EPSD	COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	O75179	ANKRD17	P24941	CDK2	T2279	S2272P	2272	Missense	distal	-7	no	10.431	10.611	EPSD	COSMIC;GDSC;CCLE	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	O75179	ANKRD17	P24941	CDK2	T2279	G2286W	2286	Missense	distal	7	no	10.431	10.650	EPSD	COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	O75179	ANKRD17	P24941	CDK2	S2318	P2311A	2311	Missense	distal	-7	no	10.816	10.980	EPSD	COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	O75179	ANKRD17	P24941	CDK2	S2318	P2319L	2319	Missense	proximal	1	no	10.816	0.995	EPSD	COSMIC	8.148	Loss
CMGC_CDK_CDK2_CDK2_ST	O75179	ANKRD17	P24941	CDK2	S2318	Q2313H	2313	Missense	distal	-5	no	10.816	10.863	EPSD	COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	O75179	ANKRD17	P24941	CDK2	S2318	G2321R	2321	Missense	distal	3	no	10.816	12.635	EPSD	COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	O75179	ANKRD17	P24941	CDK2	S2318	I2322N	2322	Missense	distal	4	no	10.816	10.824	EPSD	COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	O75179	ANKRD17	P24941	CDK2	S2318	P2317S	2317	Missense	proximal	-1	no	10.816	10.345	EPSD	COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	O75179	ANKRD17	P24941	CDK2	S2318	M2325V	2325	Missense	distal	7	no	10.816	10.529	EPSD	COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	O75179	ANKRD17	P24941	CDK2	S2373	P2374L	2374	Missense	proximal	1	no	12.223	2.402	EPSD	COSMIC	8.148	Loss
CMGC_CDK_CDK2_CDK2_ST	O75179	ANKRD17	P24941	CDK2	S2373	P2374Q	2374	Missense	proximal	1	no	12.223	4.312	EPSD	COSMIC	8.148	Loss
CMGC_CDK_CDK2_CDK2_ST	O75179	ANKRD17	P24941	CDK2	S2373	P2380S	2380	Missense	distal	7	no	12.223	12.071	EPSD	COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	O75179	ANKRD17	P24941	CDK2	T2379	P2374L	2374	Missense	distal	-5	no	11.366	11.378	EPSD	COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	O75179	ANKRD17	P24941	CDK2	T2379	P2374Q	2374	Missense	distal	-5	no	11.366	11.367	EPSD	COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	O75179	ANKRD17	P24941	CDK2	T2379	N2386I	2386	Missense	distal	7	no	11.366	11.517	EPSD	COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	O75179	ANKRD17	P24941	CDK2	T2379	P2380S	2380	Missense	proximal	1	no	11.366	0.101	EPSD	COSMIC	8.148	Loss
CMGC_CDK_CDK2_CDK2_ST	O75179	ANKRD17	P24941	CDK2	S2401	R2398H	2398	Missense	distal	-3	no	15.616	15.573	PhosphoSitePlus;EPSD	COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	O75179	ANKRD17	P24941	CDK2	S2401	P2408Q	2408	Missense	distal	7	no	15.616	15.461	PhosphoSitePlus;EPSD	COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	O75179	ANKRD17	P24941	CDK2	S2401	P2402S	2402	Missense	proximal	1	no	15.616	4.350	PhosphoSitePlus;EPSD	COSMIC	8.148	Loss
CMGC_CDK_CDK2_CDK2_ST	O75179	ANKRD17	P24941	CDK2	S2418	P2424A	2424	Missense	distal	6	no	9.260	9.256	EPSD	COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	O75179	ANKRD17	P24941	CDK2	S2418	N2416S	2416	Missense	proximal	-2	no	9.260	9.952	EPSD	COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	O75179	ANKRD17	P24941	CDK2	S2418	R2421M	2421	Missense	distal	3	no	9.260	7.302	EPSD	COSMIC	8.148	Loss
CMGC_CDK_CDK2_CDK2_ST	O75179	ANKRD17	P24941	CDK2	S2457	S2461F	2461	Missense	distal	4	no	8.591	8.395	EPSD	COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	O75179	ANKRD17	P24941	CDK2	T2509	S2511F	2511	Missense	proximal	2	no	14.493	14.677	EPSD	COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	O75179	ANKRD17	P24941	CDK2	T2509	G2512A	2512	Missense	distal	3	no	14.493	14.082	EPSD	COSMIC;GDSC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	O75179	ANKRD17	P24941	CDK2	T2509	P2510L	2510	Missense	proximal	1	no	14.493	4.672	EPSD	COSMIC	8.148	Loss
CMGC_CDK_CDK2_CDK2_ST	O75179	ANKRD17	P24941	CDK2	T2509	G2506A	2506	Missense	distal	-3	no	14.493	14.331	EPSD	COSMIC;GDSC;CCLE	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	O14757	CHEK1	P24941	CDK2	S301	F300L	300	Missense	proximal	-1	no	16.125	15.160	EPSD;PhosphoSitePlus	COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	O14757	CHEK1	P24941	CDK2	S301	P302A	302	Missense	proximal	1	no	16.125	1.722	EPSD;PhosphoSitePlus	COSMIC	8.148	Loss
CMGC_CDK_CDK2_CDK2_ST	O14757	CHEK1	P24941	CDK2	S301	S308I	308	Missense	distal	7	no	16.125	16.334	EPSD;PhosphoSitePlus	COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	O14757	CHEK1	P24941	CDK2	S301	S307F	307	Missense	distal	6	no	16.125	16.106	EPSD;PhosphoSitePlus	COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	O14757	CHEK1	P24941	CDK2	S317	E320K	320	Missense	distal	3	no	7.310	9.396	EPSD	COSMIC	8.148	Gain
CMGC_CDK_CDK2_CDK2_ST	O14757	CHEK1	P24941	CDK2	S331	S326F	326	Missense	distal	-5	no	13.309	13.426	EPSD	COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	O14757	CHEK1	P24941	CDK2	S331	P332L	332	Missense	proximal	1	no	13.309	3.488	EPSD	COSMIC	8.148	Loss
CMGC_CDK_CDK2_CDK2_ST	O14757	CHEK1	P24941	CDK2	T362	L360F	360	Missense	proximal	-2	no	11.394	10.506	EPSD	COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	O14757	CHEK1	P24941	CDK2	T362	G361D	361	Missense	proximal	-1	no	11.394	11.101	EPSD	COSMIC;GDSC;CCLE	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	Q969V6	MRTFA	P24941	CDK2	S6	L4F	4	Missense	proximal	-2	no	11.318	10.430	EPSD	COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	Q969V6	MRTFA	P24941	CDK2	S6	P2S	2	Missense	distal	-4	no	11.318	11.673	EPSD	COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	Q969V6	MRTFA	P24941	CDK2	S6	E12D	12	Missense	distal	6	no	11.318	11.306	EPSD	COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	Q969V6	MRTFA	P24941	CDK2	S6	P2L	2	Missense	distal	-4	no	11.318	11.260	EPSD	COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	Q969V6	MRTFA	P24941	CDK2	S6	K5E	5	Missense	proximal	-1	no	11.318	12.204	EPSD	COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	Q969V6	MRTFA	P24941	CDK2	S6	P2R	2	Missense	distal	-4	no	11.318	11.076	EPSD	COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	Q969V6	MRTFA	P24941	CDK2	S124	E126G	126	Missense	proximal	2	no	13.589	13.610	EPSD	COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	Q969V6	MRTFA	P24941	CDK2	S124	E126K	126	Missense	proximal	2	no	13.589	13.351	EPSD	COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	Q969V6	MRTFA	P24941	CDK2	S124	P125L	125	Missense	proximal	1	no	13.589	3.768	EPSD	COSMIC	8.148	Loss
CMGC_CDK_CDK2_CDK2_ST	Q969V6	MRTFA	P24941	CDK2	S124	D121N	121	Missense	distal	-3	no	13.589	13.544	EPSD	COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	Q969V6	MRTFA	P24941	CDK2	S124	E117K	117	Missense	distal	-7	no	13.589	13.451	EPSD	COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	Q969V6	MRTFA	P24941	CDK2	S130	E126G	126	Missense	distal	-4	no	8.805	8.256	EPSD	COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	Q969V6	MRTFA	P24941	CDK2	S130	E126K	126	Missense	distal	-4	no	8.805	8.493	EPSD	COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	Q969V6	MRTFA	P24941	CDK2	S130	P125L	125	Missense	distal	-5	no	8.805	8.816	EPSD	COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	Q969V6	MRTFA	P24941	CDK2	S139	P138L	138	Missense	proximal	-1	no	15.056	14.876	EPSD	COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	Q969V6	MRTFA	P24941	CDK2	S139	R144G	144	Missense	distal	5	no	15.056	15.076	EPSD	COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	Q969V6	MRTFA	P24941	CDK2	S156	P157H	157	Missense	proximal	1	no	13.134	6.375	EPSD	COSMIC	8.148	Loss
CMGC_CDK_CDK2_CDK2_ST	Q969V6	MRTFA	P24941	CDK2	S156	S154C	154	Missense	proximal	-2	no	13.134	12.723	EPSD	COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	Q969V6	MRTFA	P24941	CDK2	S156	P157S	157	Missense	proximal	1	no	13.134	1.868	EPSD	COSMIC	8.148	Loss
CMGC_CDK_CDK2_CDK2_ST	Q969V6	MRTFA	P24941	CDK2	S156	Q163P	163	Missense	distal	7	no	13.134	13.288	EPSD	COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	Q969V6	MRTFA	P24941	CDK2	S162	Q163P	163	Missense	proximal	1	no	5.519	13.431	EPSD	COSMIC	8.148	Gain
CMGC_CDK_CDK2_CDK2_ST	Q969V6	MRTFA	P24941	CDK2	T204	P205S	205	Missense	proximal	1	no	10.629	-0.637	EPSD	COSMIC	8.148	Loss
CMGC_CDK_CDK2_CDK2_ST	Q969V6	MRTFA	P24941	CDK2	T204	P205H	205	Missense	proximal	1	no	10.629	3.871	EPSD	COSMIC	8.148	Loss
CMGC_CDK_CDK2_CDK2_ST	Q969V6	MRTFA	P24941	CDK2	T204	K202T	202	Missense	proximal	-2	no	10.629	11.110	EPSD	COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	Q969V6	MRTFA	P24941	CDK2	T204	K202E	202	Missense	proximal	-2	no	10.629	10.028	EPSD	COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	Q969V6	MRTFA	P24941	CDK2	T204	P205L	205	Missense	proximal	1	no	10.629	0.808	EPSD	COSMIC	8.148	Loss
CMGC_CDK_CDK2_CDK2_ST	Q969V6	MRTFA	P24941	CDK2	T305	P307S	307	Missense	proximal	2	no	14.640	14.706	EPSD	COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	Q969V6	MRTFA	P24941	CDK2	T305	R309C	309	Missense	distal	4	no	14.640	14.013	EPSD	COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	Q969V6	MRTFA	P24941	CDK2	T305	E298K	298	Missense	distal	-7	no	14.640	14.502	EPSD	COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	Q969V6	MRTFA	P24941	CDK2	T305	S312P	312	Missense	distal	7	no	14.640	14.792	EPSD	COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	Q969V6	MRTFA	P24941	CDK2	T305	S302R	302	Missense	distal	-3	no	14.640	14.733	EPSD	COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	Q969V6	MRTFA	P24941	CDK2	T305	S303R	303	Missense	proximal	-2	no	14.640	14.055	EPSD	COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	Q969V6	MRTFA	P24941	CDK2	S367	R362Q	362	Missense	distal	-5	no	11.353	11.307	EPSD	COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	Q969V6	MRTFA	P24941	CDK2	S367	P365L	365	Missense	proximal	-2	no	11.353	11.129	EPSD	COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	Q969V6	MRTFA	P24941	CDK2	S367	G368A	368	Missense	proximal	1	no	11.353	4.262	EPSD	COSMIC	8.148	Loss
CMGC_CDK_CDK2_CDK2_ST	Q969V6	MRTFA	P24941	CDK2	S385	P391L	391	Missense	distal	6	no	13.065	13.066	EPSD	COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	Q969V6	MRTFA	P24941	CDK2	T450	P457S	457	Missense	distal	7	no	13.386	13.234	EPSD	COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	Q969V6	MRTFA	P24941	CDK2	T450	G448S	448	Missense	proximal	-2	no	13.386	13.477	EPSD	COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	Q969V6	MRTFA	P24941	CDK2	T450	P451S	451	Missense	proximal	1	no	13.386	2.120	EPSD	COSMIC	8.148	Loss
CMGC_CDK_CDK2_CDK2_ST	Q969V6	MRTFA	P24941	CDK2	T450	T447M	447	Missense	distal	-3	no	13.386	13.794	EPSD	COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	Q969V6	MRTFA	P24941	CDK2	T450	P452S	452	Missense	proximal	2	no	13.386	13.453	EPSD	COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	Q969V6	MRTFA	P24941	CDK2	S454	P457S	457	Missense	distal	3	no	13.602	13.636	EPSD	COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	Q969V6	MRTFA	P24941	CDK2	S454	R460H	460	Missense	distal	6	no	13.602	13.614	EPSD	COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	Q969V6	MRTFA	P24941	CDK2	S454	G448S	448	Missense	distal	-6	no	13.602	13.599	EPSD	COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	Q969V6	MRTFA	P24941	CDK2	S454	P451S	451	Missense	distal	-3	no	13.602	13.697	EPSD	COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	Q969V6	MRTFA	P24941	CDK2	S454	R460L	460	Missense	distal	6	no	13.602	13.620	EPSD	COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	Q969V6	MRTFA	P24941	CDK2	S454	T447M	447	Missense	distal	-7	no	13.602	14.106	EPSD	COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	Q969V6	MRTFA	P24941	CDK2	S454	P452S	452	Missense	proximal	-2	no	13.602	12.951	EPSD	COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	Q969V6	MRTFA	P24941	CDK2	T456	P457S	457	Missense	proximal	1	no	15.076	3.810	EPSD	COSMIC	8.148	Loss
CMGC_CDK_CDK2_CDK2_ST	Q969V6	MRTFA	P24941	CDK2	T456	R460H	460	Missense	distal	4	no	15.076	14.959	EPSD	COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	Q969V6	MRTFA	P24941	CDK2	T456	P451S	451	Missense	distal	-5	no	15.076	15.032	EPSD	COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	Q969V6	MRTFA	P24941	CDK2	T456	R460L	460	Missense	distal	4	no	15.076	15.308	EPSD	COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	Q969V6	MRTFA	P24941	CDK2	T456	P452S	452	Missense	distal	-4	no	15.076	15.431	EPSD	COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	Q969V6	MRTFA	P24941	CDK2	T471	G477C	477	Missense	distal	6	no	12.238	12.235	EPSD	COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	Q969V6	MRTFA	P24941	CDK2	T471	G473V	473	Missense	proximal	2	no	12.238	12.242	EPSD	COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	Q969V6	MRTFA	P24941	CDK2	T471	P472H	472	Missense	proximal	1	no	12.238	5.479	EPSD	COSMIC	8.148	Loss
CMGC_CDK_CDK2_CDK2_ST	Q969V6	MRTFA	P24941	CDK2	T471	G473R	473	Missense	proximal	2	no	12.238	12.279	EPSD	COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	Q969V6	MRTFA	P24941	CDK2	T471	E468D	468	Missense	distal	-3	no	12.238	12.128	EPSD	COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	Q969V6	MRTFA	P24941	CDK2	T471	D474G	474	Missense	distal	3	no	12.238	13.950	EPSD	COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	Q969V6	MRTFA	P24941	CDK2	T471	E468K	468	Missense	distal	-3	no	12.238	12.022	EPSD	COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	Q969V6	MRTFA	P24941	CDK2	T471	D474Y	474	Missense	distal	3	no	12.238	13.306	EPSD	COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	Q969V6	MRTFA	P24941	CDK2	T471	P472T	472	Missense	proximal	1	no	12.238	2.280	EPSD	COSMIC	8.148	Loss
CMGC_CDK_CDK2_CDK2_ST	Q969V6	MRTFA	P24941	CDK2	S482	G477C	477	Missense	distal	-5	no	12.400	12.401	EPSD	COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	Q969V6	MRTFA	P24941	CDK2	S482	M479T	479	Missense	distal	-3	no	12.400	11.992	EPSD	COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	Q969V6	MRTFA	P24941	CDK2	S482	T485M	485	Missense	distal	3	no	12.400	12.274	EPSD	COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	Q969V6	MRTFA	P24941	CDK2	S482	L489P	489	Missense	distal	7	no	12.400	12.369	EPSD	COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	Q969V6	MRTFA	P24941	CDK2	S482	T488A	488	Missense	distal	6	no	12.400	12.388	EPSD	COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	Q969V6	MRTFA	P24941	CDK2	S482	T485A	485	Missense	distal	3	no	12.400	12.002	EPSD	COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	Q969V6	MRTFA	P24941	CDK2	S482	P483H	483	Missense	proximal	1	no	12.400	5.641	EPSD	COSMIC	8.148	Loss
CMGC_CDK_CDK2_CDK2_ST	Q969V6	MRTFA	P24941	CDK2	S482	T488M	488	Missense	distal	6	no	12.400	12.373	EPSD	COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	Q969V6	MRTFA	P24941	CDK2	S511	A516G	516	Missense	distal	5	no	15.133	15.250	EPSD	COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	Q969V6	MRTFA	P24941	CDK2	S511	A516T	516	Missense	distal	5	no	15.133	15.097	EPSD	COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	Q969V6	MRTFA	P24941	CDK2	S511	P512H	512	Missense	proximal	1	no	15.133	8.375	EPSD	COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	Q969V6	MRTFA	P24941	CDK2	S511	G513E	513	Missense	proximal	2	no	15.133	15.112	EPSD	COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	Q969V6	MRTFA	P24941	CDK2	S511	P512S	512	Missense	proximal	1	no	15.133	3.867	EPSD	COSMIC	8.148	Loss
CMGC_CDK_CDK2_CDK2_ST	Q969V6	MRTFA	P24941	CDK2	S511	L518V	518	Missense	distal	7	no	15.133	15.361	EPSD	COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	Q969V6	MRTFA	P24941	CDK2	S511	C509Y	509	Missense	proximal	-2	no	15.133	15.630	EPSD	COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	Q969V6	MRTFA	P24941	CDK2	S511	R515L	515	Missense	distal	4	no	15.133	15.365	EPSD	COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	Q969V6	MRTFA	P24941	CDK2	S511	R504L	504	Missense	distal	-7	no	15.133	14.795	EPSD	COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	Q969V6	MRTFA	P24941	CDK2	S511	A516V	516	Missense	distal	5	no	15.133	15.090	EPSD	COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	Q969V6	MRTFA	P24941	CDK2	S511	R515Q	515	Missense	distal	4	no	15.133	15.314	EPSD	COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	Q969V6	MRTFA	P24941	CDK2	S511	R515W	515	Missense	distal	4	no	15.133	14.773	EPSD	COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	Q969V6	MRTFA	P24941	CDK2	S511	G514E	514	Missense	distal	3	no	15.133	15.856	EPSD	COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	Q969V6	MRTFA	P24941	CDK2	T573	L571P	571	Missense	proximal	-2	no	15.267	15.492	PhosphoSitePlus	COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	Q969V6	MRTFA	P24941	CDK2	T573	A569P	569	Missense	distal	-4	no	15.267	15.326	PhosphoSitePlus	COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	Q969V6	MRTFA	P24941	CDK2	T573	K576R	576	Missense	distal	3	no	15.267	14.278	PhosphoSitePlus	COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	Q969V6	MRTFA	P24941	CDK2	T573	A567P	567	Missense	distal	-6	no	15.267	15.269	PhosphoSitePlus	COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	Q969V6	MRTFA	P24941	CDK2	T573	P566L	566	Missense	distal	-7	no	15.267	15.273	PhosphoSitePlus	COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	Q969V6	MRTFA	P24941	CDK2	T573	T573M	573	Missense	central	0	yes	15.267	0.000	PhosphoSitePlus	COSMIC	8.148	Loss
CMGC_CDK_CDK2_CDK2_ST	Q969V6	MRTFA	P24941	CDK2	S695	S695L	695	Missense	central	0	yes	18.183	0.000	EPSD	COSMIC	8.148	Loss
CMGC_CDK_CDK2_CDK2_ST	Q969V6	MRTFA	P24941	CDK2	S695	A699V	699	Missense	distal	4	no	18.183	18.370	EPSD	COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	Q969V6	MRTFA	P24941	CDK2	S695	P698R	698	Missense	distal	3	no	18.183	19.902	EPSD	COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	Q969V6	MRTFA	P24941	CDK2	S695	S701F	701	Missense	distal	6	no	18.183	18.164	EPSD	COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	Q969V6	MRTFA	P24941	CDK2	S695	A702G	702	Missense	distal	7	no	18.183	18.468	EPSD	COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	Q969V6	MRTFA	P24941	CDK2	S695	S695I	695	Missense	central	0	yes	18.183	0.000	EPSD	COSMIC	8.148	Loss
CMGC_CDK_CDK2_CDK2_ST	Q969V6	MRTFA	P24941	CDK2	S733	A731T	731	Missense	proximal	-2	no	9.238	9.188	EPSD	COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	Q969V6	MRTFA	P24941	CDK2	S733	Q734K	734	Missense	proximal	1	no	9.238	-0.500	EPSD	COSMIC	8.148	Loss
CMGC_CDK_CDK2_CDK2_ST	Q969V6	MRTFA	P24941	CDK2	S733	P726L	726	Missense	distal	-7	no	9.238	9.244	EPSD	COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	Q969V6	MRTFA	P24941	CDK2	S733	P726S	726	Missense	distal	-7	no	9.238	9.058	EPSD	COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	Q969V6	MRTFA	P24941	CDK2	S733	Q735K	735	Missense	proximal	2	no	9.238	9.038	EPSD	COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	Q969V6	MRTFA	P24941	CDK2	S785	P779L	779	Missense	distal	-6	no	14.272	14.271	EPSD	COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	Q969V6	MRTFA	P24941	CDK2	S785	S785P	785	Missense	central	0	yes	14.272	0.000	EPSD	COSMIC	8.148	Loss
CMGC_CDK_CDK2_CDK2_ST	Q969V6	MRTFA	P24941	CDK2	S785	P779S	779	Missense	distal	-6	no	14.272	14.271	EPSD	COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	Q969V6	MRTFA	P24941	CDK2	S792	S785P	785	Missense	distal	-7	no	12.983	13.163	EPSD	COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	Q969V6	MRTFA	P24941	CDK2	S807	R813C	813	Missense	distal	6	no	16.294	16.296	EPSD	COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	Q969V6	MRTFA	P24941	CDK2	S807	P808T	808	Missense	proximal	1	no	16.294	6.336	EPSD	COSMIC	8.148	Loss
CMGC_CDK_CDK2_CDK2_ST	Q969V6	MRTFA	P24941	CDK2	S807	P805A	805	Missense	proximal	-2	no	16.294	16.310	EPSD	COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	Q969V6	MRTFA	P24941	CDK2	S807	S809P	809	Missense	proximal	2	no	16.294	16.227	EPSD	COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	Q969V6	MRTFA	P24941	CDK2	S807	P803L	803	Missense	distal	-4	no	16.294	16.235	EPSD	COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	Q969V6	MRTFA	P24941	CDK2	S859	S859P	859	Missense	central	0	yes	13.745	0.000	EPSD	COSMIC	8.148	Loss
CMGC_CDK_CDK2_CDK2_ST	Q969V6	MRTFA	P24941	CDK2	S859	H856R	856	Missense	distal	-3	no	13.745	13.787	EPSD	COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	Q969V6	MRTFA	P24941	CDK2	S859	I853V	853	Missense	distal	-6	no	13.745	13.744	EPSD	COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	Q5JTZ9	AARS2	P24941	CDK2	T673	V680E	680	Missense	distal	7	no	14.099	13.885	PhosphoSitePlus	COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	Q5JTZ9	AARS2	P24941	CDK2	S916	V923M	923	Missense	distal	7	no	12.922	13.208	EPSD	COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	Q14202	ZMYM3	P24941	CDK2	S8	P3H	3	Missense	distal	-5	no	10.302	10.349	EPSD	COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	Q14202	ZMYM3	P24941	CDK2	S51	A56S	56	Missense	distal	5	no	15.483	15.372	EPSD	COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	Q14202	ZMYM3	P24941	CDK2	S54	A56S	56	Missense	proximal	2	no	8.853	8.894	EPSD	COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	Q14202	ZMYM3	P24941	CDK2	T62	G65S	65	Missense	distal	3	no	15.713	15.848	EPSD	COSMIC;GDSC;CCLE	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	Q14202	ZMYM3	P24941	CDK2	S91	P93S	93	Missense	proximal	2	no	16.805	16.872	EPSD	COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	Q14202	ZMYM3	P24941	CDK2	S148	T151P	151	Missense	distal	3	no	13.911	14.025	EPSD	COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	Q14202	ZMYM3	P24941	CDK2	S154	T151P	151	Missense	distal	-3	no	11.857	11.897	EPSD	COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	Q14202	ZMYM3	P24941	CDK2	S186	P190L	190	Missense	distal	4	no	13.368	13.480	EPSD	COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	Q14202	ZMYM3	P24941	CDK2	S192	P190L	190	Missense	proximal	-2	no	13.959	13.735	EPSD	COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	Q14202	ZMYM3	P24941	CDK2	S192	V195M	195	Missense	distal	3	no	13.959	13.111	EPSD	COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	Q14202	ZMYM3	P24941	CDK2	S214	P216R	216	Missense	proximal	2	no	11.689	11.848	EPSD	COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	Q14202	ZMYM3	P24941	CDK2	S263	D266V	266	Missense	distal	3	no	8.114	10.536	EPSD	COSMIC	8.148	Gain
CMGC_CDK_CDK2_CDK2_ST	Q14202	ZMYM3	P24941	CDK2	S287	R285W	285	Missense	proximal	-2	no	12.458	11.959	EPSD	COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	Q14202	ZMYM3	P24941	CDK2	S287	R283W	283	Missense	distal	-4	no	12.458	11.700	EPSD	COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	Q14202	ZMYM3	P24941	CDK2	S287	S287F	287	Missense	central	0	yes	12.458	0.000	EPSD	COSMIC	8.148	Loss
CMGC_CDK_CDK2_CDK2_ST	Q14202	ZMYM3	P24941	CDK2	T316	A312T	312	Missense	distal	-4	no	16.088	16.314	EPSD	COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	Q14202	ZMYM3	P24941	CDK2	T316	G321E	321	Missense	distal	5	no	16.088	16.041	EPSD	COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	Q14202	ZMYM3	P24941	CDK2	S582	E584D	584	Missense	proximal	2	no	11.093	10.993	EPSD	COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	Q14202	ZMYM3	P24941	CDK2	S582	G585E	585	Missense	distal	3	no	11.093	11.816	EPSD	COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	Q14202	ZMYM3	P24941	CDK2	S753	Q754P	754	Missense	proximal	1	no	4.077	11.989	EPSD	COSMIC	8.148	Gain
CMGC_CDK_CDK2_CDK2_ST	Q14202	ZMYM3	P24941	CDK2	S774	T781R	781	Missense	distal	7	no	12.518	13.311	EPSD	COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	Q14202	ZMYM3	P24941	CDK2	T781	Q784E	784	Missense	distal	3	no	14.713	15.360	EPSD	COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	Q14202	ZMYM3	P24941	CDK2	T781	T781R	781	Missense	central	0	yes	14.713	0.000	EPSD	COSMIC	8.148	Loss
CMGC_CDK_CDK2_CDK2_ST	Q14202	ZMYM3	P24941	CDK2	T781	Q784K	784	Missense	distal	3	no	14.713	17.446	EPSD	COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	Q14202	ZMYM3	P24941	CDK2	T795	T792A	792	Missense	distal	-3	no	12.666	12.648	EPSD	COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	Q14202	ZMYM3	P24941	CDK2	T795	E797D	797	Missense	proximal	2	no	12.666	12.567	EPSD	COSMIC;GDSC;CCLE	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	Q14202	ZMYM3	P24941	CDK2	T795	G800W	800	Missense	distal	5	no	12.666	12.813	EPSD	COSMIC;CCLE	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	Q14202	ZMYM3	P24941	CDK2	T795	E797K	797	Missense	proximal	2	no	12.666	12.429	EPSD	COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	Q14202	ZMYM3	P24941	CDK2	T795	P796Q	796	Missense	proximal	1	no	12.666	4.755	EPSD	COSMIC	8.148	Loss
CMGC_CDK_CDK2_CDK2_ST	Q14202	ZMYM3	P24941	CDK2	T826	A833V	833	Missense	distal	7	no	15.734	15.608	PhosphoSitePlus	COSMIC;GDSC;CCLE	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	P15336	ATF2	P24941	CDK2	T69	T73A	73	Missense	distal	4	no	14.316	14.073	EPSD	COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	P15336	ATF2	P24941	CDK2	T69	F75L	75	Missense	distal	6	no	14.316	14.335	EPSD	COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	P15336	ATF2	P24941	CDK2	T69	R74T	74	Missense	distal	5	no	14.316	14.184	EPSD	COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	P15336	ATF2	P24941	CDK2	T69	I64V	64	Missense	distal	-5	no	14.316	14.307	EPSD	COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	P15336	ATF2	P24941	CDK2	T69	D67E	67	Missense	proximal	-2	no	14.316	13.335	EPSD	COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	P15336	ATF2	P24941	CDK2	T71	T73A	73	Missense	proximal	2	no	14.670	14.872	EPSD	COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	P15336	ATF2	P24941	CDK2	T71	F75L	75	Missense	distal	4	no	14.670	14.964	EPSD	COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	P15336	ATF2	P24941	CDK2	T71	R74T	74	Missense	distal	3	no	14.670	12.837	EPSD	COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	P15336	ATF2	P24941	CDK2	T71	I64V	64	Missense	distal	-7	no	14.670	14.495	EPSD	COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	P15336	ATF2	P24941	CDK2	T71	D67E	67	Missense	distal	-4	no	14.670	14.373	EPSD	COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	P15336	ATF2	P24941	CDK2	S90	P91S	91	Missense	proximal	1	no	15.244	3.978	EPSD	COSMIC	8.148	Loss
CMGC_CDK_CDK2_CDK2_ST	P15336	ATF2	P24941	CDK2	S90	A89V	89	Missense	proximal	-1	no	15.244	15.471	EPSD	COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	P15336	ATF2	P24941	CDK2	S90	P91L	91	Missense	proximal	1	no	15.244	5.423	EPSD	COSMIC	8.148	Loss
CMGC_CDK_CDK2_CDK2_ST	P15336	ATF2	P24941	CDK2	S90	G83C	83	Missense	distal	-7	no	15.244	15.190	EPSD	COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	P15336	ATF2	P24941	CDK2	S112	M107I	107	Missense	distal	-5	no	14.689	14.621	EPSD	COSMIC;GDSC;CCLE	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	P15336	ATF2	P24941	CDK2	S112	K105T	105	Missense	distal	-7	no	14.689	14.733	EPSD	COSMIC;GDSC;CCLE	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	P15336	ATF2	P24941	CDK2	S112	K106R	106	Missense	distal	-6	no	14.689	14.691	EPSD	COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	P15336	ATF2	P24941	CDK2	S112	D110E	110	Missense	proximal	-2	no	14.689	13.708	EPSD	COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	P15336	ATF2	P24941	CDK2	T116	D110E	110	Missense	distal	-6	no	12.048	12.052	PhosphoSitePlus	COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	P15336	ATF2	P24941	CDK2	S136	P141T	141	Missense	distal	5	no	12.538	12.512	EPSD	COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	P15336	ATF2	P24941	CDK2	S136	P141L	141	Missense	distal	5	no	12.538	12.578	EPSD	COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	P15336	ATF2	P24941	CDK2	S136	P137S	137	Missense	proximal	1	no	12.538	1.272	EPSD	COSMIC	8.148	Loss
CMGC_CDK_CDK2_CDK2_ST	P15336	ATF2	P24941	CDK2	S265	S266P	266	Missense	proximal	1	no	1.137	12.403	EPSD	COSMIC	8.148	Gain
CMGC_CDK_CDK2_CDK2_ST	P15336	ATF2	P24941	CDK2	S266	S266P	266	Missense	central	0	yes	12.962	0.000	EPSD	COSMIC	8.148	Loss
CMGC_CDK_CDK2_CDK2_ST	P15336	ATF2	P24941	CDK2	S266	P269Q	269	Missense	distal	3	no	12.962	12.937	EPSD	COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	P15336	ATF2	P24941	CDK2	S266	S265F	265	Missense	proximal	-1	no	12.962	14.219	EPSD	COSMIC;GDSC;CCLE	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	P15336	ATF2	P24941	CDK2	S266	P269S	269	Missense	distal	3	no	12.962	12.996	EPSD	COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	P15336	ATF2	P24941	CDK2	T325	P326L	326	Missense	proximal	1	no	13.346	3.525	EPSD	COSMIC;GDSC	8.148	Loss
CMGC_CDK_CDK2_CDK2_ST	P15336	ATF2	P24941	CDK2	T325	P326T	326	Missense	proximal	1	no	13.346	3.389	EPSD	COSMIC	8.148	Loss
CMGC_CDK_CDK2_CDK2_ST	P15336	ATF2	P24941	CDK2	T325	H331Y	331	Missense	distal	6	no	13.346	13.343	EPSD	COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	P15336	ATF2	P24941	CDK2	S328	P326L	326	Missense	proximal	-2	no	12.868	12.644	EPSD	COSMIC;GDSC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	P15336	ATF2	P24941	CDK2	S328	P326T	326	Missense	proximal	-2	no	12.868	12.835	EPSD	COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	P15336	ATF2	P24941	CDK2	S328	Q335H	335	Missense	distal	7	no	12.868	13.154	EPSD	COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	P15336	ATF2	P24941	CDK2	S328	P334S	334	Missense	distal	6	no	12.868	12.869	EPSD	COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	P15336	ATF2	P24941	CDK2	S328	H331Y	331	Missense	distal	3	no	12.868	11.101	EPSD	COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	P15336	ATF2	P24941	CDK2	T333	Q337K	337	Missense	distal	4	no	11.689	12.029	EPSD	COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	P15336	ATF2	P24941	CDK2	T333	P326L	326	Missense	distal	-7	no	11.689	11.694	EPSD	COSMIC;GDSC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	P15336	ATF2	P24941	CDK2	T333	P326T	326	Missense	distal	-7	no	11.689	11.686	EPSD	COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	P15336	ATF2	P24941	CDK2	T333	Q335H	335	Missense	proximal	2	no	11.689	11.707	EPSD	COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	P15336	ATF2	P24941	CDK2	T333	P334S	334	Missense	proximal	1	no	11.689	0.423	EPSD	COSMIC	8.148	Loss
CMGC_CDK_CDK2_CDK2_ST	P15336	ATF2	P24941	CDK2	T333	H331Y	331	Missense	proximal	-2	no	11.689	12.134	EPSD	COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	P15336	ATF2	P24941	CDK2	S446	S442L	442	Missense	distal	-4	no	12.249	11.836	EPSD	COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	P15336	ATF2	P24941	CDK2	S446	P444L	444	Missense	proximal	-2	no	12.249	12.025	EPSD	COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	P15336	ATF2	P24941	CDK2	S446	P444T	444	Missense	proximal	-2	no	12.249	12.216	EPSD	COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	P15336	ATF2	P24941	CDK2	S446	S442P	442	Missense	distal	-4	no	12.249	11.895	EPSD	COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	P15336	ATF2	P24941	CDK2	S446	P444Q	444	Missense	proximal	-2	no	12.249	11.682	EPSD	COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	Q9UKM9	RALY	P24941	CDK2	S135	G132V	132	Missense	distal	-3	no	14.880	14.920	PhosphoSitePlus	COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	Q9UKM9	RALY	P24941	CDK2	S206	R207H	207	Missense	proximal	1	no	6.802	9.842	EPSD	COSMIC	8.148	Gain
CMGC_CDK_CDK2_CDK2_ST	Q9UKM9	RALY	P24941	CDK2	S244	G248S	248	Missense	distal	4	no	8.134	8.268	EPSD	COSMIC	8.148	Gain
CMGC_CDK_CDK2_CDK2_ST	Q9UKM9	RALY	P24941	CDK2	S244	G240S	240	Missense	distal	-4	no	8.134	8.807	EPSD	COSMIC	8.148	Gain
CMGC_CDK_CDK2_CDK2_ST	Q9UKM9	RALY	P24941	CDK2	T286	L284F	284	Missense	proximal	-2	no	9.134	8.246	EPSD	COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	P78317	RNF4	P24941	CDK2	T112	P113L	113	Missense	proximal	1	no	14.391	4.571	EPSD;PhosphoSitePlus	COSMIC	8.148	Loss
CMGC_CDK_CDK2_CDK2_ST	P78317	RNF4	P24941	CDK2	T112	R117M	117	Missense	distal	5	no	14.391	14.593	EPSD;PhosphoSitePlus	COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	Q13352	ITGB3BP	P24941	CDK2	S33	S28N	28	Missense	distal	-5	no	13.351	13.415	EPSD;PhosphoSitePlus	COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	Q13352	ITGB3BP	P24941	CDK2	S33	P34Q	34	Missense	proximal	1	no	13.351	5.440	EPSD;PhosphoSitePlus	COSMIC	8.148	Loss
CMGC_CDK_CDK2_CDK2_ST	Q13352	ITGB3BP	P24941	CDK2	S46	P47R	47	Missense	proximal	1	no	13.748	3.950	PhosphoSitePlus;EPSD	COSMIC	8.148	Loss
CMGC_CDK_CDK2_CDK2_ST	Q13352	ITGB3BP	P24941	CDK2	S46	M41I	41	Missense	distal	-5	no	13.748	13.681	PhosphoSitePlus;EPSD	COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	Q13352	ITGB3BP	P24941	CDK2	S46	A45V	45	Missense	proximal	-1	no	13.748	13.975	PhosphoSitePlus;EPSD	COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	Q13352	ITGB3BP	P24941	CDK2	T73	T80I	80	Missense	distal	7	no	7.905	8.266	EPSD	COSMIC	8.148	Gain
CMGC_CDK_CDK2_CDK2_ST	Q13352	ITGB3BP	P24941	CDK2	T73	S78F	78	Missense	distal	5	no	7.905	8.224	EPSD	COSMIC	8.148	Gain
CMGC_CDK_CDK2_CDK2_ST	P38936	CDKN1A	P24941	CDK2	T57	D62Y	62	Missense	distal	5	no	15.802	15.702	EPSD	COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	P38936	CDKN1A	P24941	CDK2	T57	D62H	62	Missense	distal	5	no	15.802	15.707	EPSD	COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	P38936	CDKN1A	P24941	CDK2	T57	D52V	52	Missense	distal	-5	no	15.802	15.776	EPSD	COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	P38936	CDKN1A	P24941	CDK2	T57	T57R	57	Missense	central	0	yes	15.802	0.000	EPSD	COSMIC	8.148	Loss
CMGC_CDK_CDK2_CDK2_ST	P38936	CDKN1A	P24941	CDK2	T80	D87E	87	Missense	distal	7	no	9.228	8.586	EPSD	COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	P38936	CDKN1A	P24941	CDK2	T80	R84Q	84	Missense	distal	4	no	9.228	9.409	EPSD	COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	P38936	CDKN1A	P24941	CDK2	T80	R86G	86	Missense	distal	6	no	9.228	9.233	EPSD	COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	P38936	CDKN1A	P24941	CDK2	T80	G85V	85	Missense	distal	5	no	9.228	9.068	EPSD	COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	P38936	CDKN1A	P24941	CDK2	T80	R86P	86	Missense	distal	6	no	9.228	9.244	EPSD	COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	P38936	CDKN1A	P24941	CDK2	T80	R83W	83	Missense	distal	3	no	9.228	6.588	EPSD	COSMIC	8.148	Loss
CMGC_CDK_CDK2_CDK2_ST	P38936	CDKN1A	P24941	CDK2	T80	Y77N	77	Missense	distal	-3	no	9.228	9.134	EPSD	COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	P38936	CDKN1A	P24941	CDK2	S98	T97I	97	Missense	proximal	-1	no	12.155	12.401	EPSD	COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	P38936	CDKN1A	P24941	CDK2	S130	E125Q	125	Missense	distal	-5	no	14.015	13.978	PhosphoSitePlus	COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	P38936	CDKN1A	P24941	CDK2	S130	S137T	137	Missense	distal	7	no	14.015	13.863	PhosphoSitePlus	COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	Q8WYH8	ING5	P24941	CDK2	S57	R64H	64	Missense	distal	7	no	12.411	12.053	EPSD	COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	Q8WYH8	ING5	P24941	CDK2	T152	K159N	159	Missense	distal	7	no	16.833	17.026	PhosphoSitePlus	COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	Q99607	ELF4	P24941	CDK2	S641	S634C	634	Missense	distal	-7	no	16.080	16.530	EPSD	COSMIC;CCLE	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	Q99607	ELF4	P24941	CDK2	T643	P649Q	649	Missense	distal	6	no	16.397	16.403	PhosphoSitePlus;EPSD	COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	Q99607	ELF4	P24941	CDK2	S648	P649Q	649	Missense	proximal	1	no	14.494	6.582	EPSD;PhosphoSitePlus	COSMIC	8.148	Loss
CMGC_CDK_CDK2_CDK2_ST	P50570	DNM2	P24941	CDK2	S116	L122F	122	Missense	distal	6	no	12.816	12.796	EPSD	COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	P50570	DNM2	P24941	CDK2	S116	T109M	109	Missense	distal	-7	no	12.816	13.319	EPSD	COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	P50570	DNM2	P24941	CDK2	S126	L122F	122	Missense	distal	-4	no	16.601	16.052	EPSD	COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	P50570	DNM2	P24941	CDK2	T280	L281P	281	Missense	proximal	1	no	3.236	13.057	EPSD	COSMIC	8.148	Gain
CMGC_CDK_CDK2_CDK2_ST	P50570	DNM2	P24941	CDK2	T353	L354P	354	Missense	proximal	1	no	3.939	13.760	EPSD	COSMIC	8.148	Gain
CMGC_CDK_CDK2_CDK2_ST	P50570	DNM2	P24941	CDK2	T404	G397L	397	Missense	distal	-7	no	16.089	15.771	EPSD	COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	P50570	DNM2	P24941	CDK2	T404	A408P	408	Missense	distal	4	no	16.089	16.050	EPSD	COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	P50570	DNM2	P24941	CDK2	T746	V744A	744	Missense	proximal	-2	no	11.528	12.194	EPSD	COSMIC;CCLE	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	P50570	DNM2	P24941	CDK2	S762	P767Q	767	Missense	distal	5	no	8.494	8.454	EPSD	COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	P50570	DNM2	P24941	CDK2	S762	T766P	766	Missense	distal	4	no	8.494	8.212	EPSD	COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	P50570	DNM2	P24941	CDK2	S762	R769H	769	Missense	distal	7	no	8.494	8.136	EPSD	COSMIC	8.148	Loss
CMGC_CDK_CDK2_CDK2_ST	P50570	DNM2	P24941	CDK2	S764	P767Q	767	Missense	distal	3	no	14.419	14.394	PhosphoSitePlus	COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	P50570	DNM2	P24941	CDK2	S764	T766P	766	Missense	proximal	2	no	14.419	14.597	PhosphoSitePlus	COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	P50570	DNM2	P24941	CDK2	S764	R769H	769	Missense	distal	5	no	14.419	14.391	PhosphoSitePlus	COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	P50570	DNM2	P24941	CDK2	T766	P767Q	767	Missense	proximal	1	no	13.426	5.515	EPSD	COSMIC	8.148	Loss
CMGC_CDK_CDK2_CDK2_ST	P50570	DNM2	P24941	CDK2	T766	T766P	766	Missense	central	0	yes	13.426	0.000	EPSD	COSMIC	8.148	Loss
CMGC_CDK_CDK2_CDK2_ST	P50570	DNM2	P24941	CDK2	T766	R769H	769	Missense	distal	3	no	13.426	12.730	EPSD	COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	Q05209	PTPN12	P24941	CDK2	S19	D26A	26	Missense	distal	7	no	12.249	11.947	PhosphoSitePlus	COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	Q05209	PTPN12	P24941	CDK2	S186	R187P	187	Missense	proximal	1	no	5.193	14.991	EPSD	COSMIC	8.148	Gain
CMGC_CDK_CDK2_CDK2_ST	Q05209	PTPN12	P24941	CDK2	S332	E326D	326	Missense	distal	-6	no	16.064	16.060	EPSD	COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	Q05209	PTPN12	P24941	CDK2	S332	P335S	335	Missense	distal	3	no	16.064	16.098	EPSD	COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	Q05209	PTPN12	P24941	CDK2	T367	L366V	366	Missense	proximal	-1	no	13.910	14.046	EPSD	COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	Q05209	PTPN12	P24941	CDK2	T367	P370S	370	Missense	distal	3	no	13.910	13.944	EPSD	COSMIC;GDSC;CCLE	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	Q05209	PTPN12	P24941	CDK2	S369	L366V	366	Missense	distal	-3	no	11.741	11.954	EPSD	COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	Q05209	PTPN12	P24941	CDK2	S369	P370S	370	Missense	proximal	1	no	11.741	0.475	EPSD	COSMIC;GDSC;CCLE	8.148	Loss
CMGC_CDK_CDK2_CDK2_ST	Q05209	PTPN12	P24941	CDK2	S468	I462N	462	Missense	distal	-6	no	12.332	12.329	EPSD	COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	Q05209	PTPN12	P24941	CDK2	S468	K463I	463	Missense	distal	-5	no	12.332	12.368	EPSD	COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	Q05209	PTPN12	P24941	CDK2	S468	K474N	474	Missense	distal	6	no	12.332	12.327	EPSD	COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	Q05209	PTPN12	P24941	CDK2	S468	I471V	471	Missense	distal	3	no	12.332	13.608	EPSD	COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	Q05209	PTPN12	P24941	CDK2	T509	P511Q	511	Missense	proximal	2	no	14.883	14.942	EPSD	COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	Q05209	PTPN12	P24941	CDK2	T569	T574A	574	Missense	distal	5	no	13.363	13.399	EPSD	COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	Q05209	PTPN12	P24941	CDK2	T569	T574I	574	Missense	distal	5	no	13.363	13.481	EPSD	COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	Q05209	PTPN12	P24941	CDK2	T569	T574P	574	Missense	distal	5	no	13.363	13.389	EPSD	COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	Q05209	PTPN12	P24941	CDK2	T569	T574S	574	Missense	distal	5	no	13.363	13.288	EPSD	COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	Q05209	PTPN12	P24941	CDK2	T569	T573A	573	Missense	distal	4	no	13.363	13.120	EPSD	COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	Q05209	PTPN12	P24941	CDK2	S571	T574A	574	Missense	distal	3	no	14.227	13.829	EPSD	COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	Q05209	PTPN12	P24941	CDK2	S571	T574I	574	Missense	distal	3	no	14.227	13.673	EPSD	COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	Q05209	PTPN12	P24941	CDK2	S571	T574P	574	Missense	distal	3	no	14.227	14.341	EPSD	COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	Q05209	PTPN12	P24941	CDK2	S571	T574S	574	Missense	distal	3	no	14.227	14.375	EPSD	COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	Q05209	PTPN12	P24941	CDK2	S571	T573A	573	Missense	proximal	2	no	14.227	14.429	EPSD	COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	Q05209	PTPN12	P24941	CDK2	T573	T574P	574	Missense	proximal	1	no	4.373	14.330	EPSD	COSMIC	8.148	Gain
CMGC_CDK_CDK2_CDK2_ST	Q05209	PTPN12	P24941	CDK2	T578	T574A	574	Missense	distal	-4	no	15.168	14.943	EPSD	COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	Q05209	PTPN12	P24941	CDK2	T578	T574I	574	Missense	distal	-4	no	15.168	14.851	EPSD	COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	Q05209	PTPN12	P24941	CDK2	T578	T574P	574	Missense	distal	-4	no	15.168	15.002	EPSD	COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	Q05209	PTPN12	P24941	CDK2	T578	T574S	574	Missense	distal	-4	no	15.168	15.356	EPSD	COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	Q05209	PTPN12	P24941	CDK2	T578	T573A	573	Missense	distal	-5	no	15.168	15.194	EPSD	COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	Q05209	PTPN12	P24941	CDK2	T578	D585G	585	Missense	distal	7	no	15.168	15.152	EPSD	COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	Q05209	PTPN12	P24941	CDK2	T578	L581I	581	Missense	distal	3	no	15.168	14.884	EPSD	COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	Q05209	PTPN12	P24941	CDK2	S588	L590I	590	Missense	proximal	2	no	13.554	13.638	EPSD	COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	Q05209	PTPN12	P24941	CDK2	S588	D585G	585	Missense	distal	-3	no	13.554	13.592	EPSD	COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	Q05209	PTPN12	P24941	CDK2	S588	L581I	581	Missense	distal	-7	no	13.554	13.743	EPSD	COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	Q05209	PTPN12	P24941	CDK2	T593	L590I	590	Missense	distal	-3	no	11.681	11.772	EPSD	COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	Q05209	PTPN12	P24941	CDK2	S608	E610A	610	Missense	proximal	2	no	9.388	9.316	EPSD	COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	Q05209	PTPN12	P24941	CDK2	S608	G615V	615	Missense	distal	7	no	9.388	8.976	EPSD	COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	Q05209	PTPN12	P24941	CDK2	S608	G615D	615	Missense	distal	7	no	9.388	9.404	EPSD	COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	Q05209	PTPN12	P24941	CDK2	S608	D604G	604	Missense	distal	-4	no	9.388	8.543	EPSD	COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	Q05209	PTPN12	P24941	CDK2	T618	G615V	615	Missense	distal	-3	no	8.697	8.736	EPSD	COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	Q05209	PTPN12	P24941	CDK2	T618	G615D	615	Missense	distal	-3	no	8.697	8.659	EPSD	COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	Q05209	PTPN12	P24941	CDK2	T618	K621E	621	Missense	distal	3	no	8.697	6.612	EPSD	COSMIC	8.148	Loss
CMGC_CDK_CDK2_CDK2_ST	Q05209	PTPN12	P24941	CDK2	S673	P676H	676	Missense	distal	3	no	11.748	12.770	EPSD	COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	Q05209	PTPN12	P24941	CDK2	S673	R680K	680	Missense	distal	7	no	11.748	10.971	EPSD	COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	Q05209	PTPN12	P24941	CDK2	S673	P678R	678	Missense	distal	5	no	11.748	11.854	EPSD	COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	Q05209	PTPN12	P24941	CDK2	T681	P676H	676	Missense	distal	-5	no	10.377	10.424	EPSD	COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	Q05209	PTPN12	P24941	CDK2	T681	R680K	680	Missense	proximal	-1	no	10.377	9.707	EPSD	COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	Q05209	PTPN12	P24941	CDK2	T681	A688V	688	Missense	distal	7	no	10.377	10.251	EPSD	COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	Q05209	PTPN12	P24941	CDK2	T681	P678R	678	Missense	distal	-3	no	10.377	10.566	EPSD	COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	Q05209	PTPN12	P24941	CDK2	T693	S697T	697	Missense	distal	4	no	14.328	14.597	EPSD	COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	Q05209	PTPN12	P24941	CDK2	T693	E698Q	698	Missense	distal	5	no	14.328	14.209	EPSD	COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	Q05209	PTPN12	P24941	CDK2	T693	W699L	699	Missense	distal	6	no	14.328	14.353	EPSD	COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	Q05209	PTPN12	P24941	CDK2	T693	T693P	693	Missense	central	0	yes	14.328	0.000	EPSD	COSMIC	8.148	Loss
CMGC_CDK_CDK2_CDK2_ST	Q05209	PTPN12	P24941	CDK2	T693	A688V	688	Missense	distal	-5	no	14.328	14.334	EPSD	COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	Q05209	PTPN12	P24941	CDK2	T693	P694H	694	Missense	proximal	1	no	14.328	7.569	EPSD	COSMIC	8.148	Loss
CMGC_CDK_CDK2_CDK2_ST	Q05209	PTPN12	P24941	CDK2	T693	T693A	693	Missense	central	0	yes	14.328	0.000	EPSD	COSMIC	8.148	Loss
CMGC_CDK_CDK2_CDK2_ST	Q05209	PTPN12	P24941	CDK2	T693	T693I	693	Missense	central	0	yes	14.328	0.000	EPSD	COSMIC	8.148	Loss
CMGC_CDK_CDK2_CDK2_ST	Q05209	PTPN12	P24941	CDK2	T693	N692K	692	Missense	proximal	-1	no	14.328	14.301	EPSD	COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	Q05209	PTPN12	P24941	CDK2	S704	S697T	697	Missense	distal	-7	no	8.016	8.193	EPSD	COSMIC	8.148	Gain
CMGC_CDK_CDK2_CDK2_ST	Q05209	PTPN12	P24941	CDK2	S704	K711R	711	Missense	distal	7	no	8.016	8.792	EPSD	COSMIC	8.148	Gain
CMGC_CDK_CDK2_CDK2_ST	Q05209	PTPN12	P24941	CDK2	S708	E706K	706	Missense	proximal	-2	no	10.006	10.607	EPSD	COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	Q05209	PTPN12	P24941	CDK2	S708	Q710K	710	Missense	proximal	2	no	10.006	9.806	EPSD	COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	Q05209	PTPN12	P24941	CDK2	S708	E714K	714	Missense	distal	6	no	10.006	10.017	EPSD	COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	Q05209	PTPN12	P24941	CDK2	S708	K711R	711	Missense	distal	3	no	10.006	9.017	EPSD	COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	Q15788	NCOA1	P24941	CDK2	S192	R189Q	189	Missense	distal	-3	no	8.752	8.622	EPSD	COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	Q15788	NCOA1	P24941	CDK2	S192	R198S	198	Missense	distal	6	no	8.752	8.770	EPSD	COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	Q15788	NCOA1	P24941	CDK2	S325	F330L	330	Missense	distal	5	no	13.440	13.262	PhosphoSitePlus;EPSD	COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	Q15788	NCOA1	P24941	CDK2	S325	R320C	320	Missense	distal	-5	no	13.440	13.473	PhosphoSitePlus;EPSD	COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	Q15788	NCOA1	P24941	CDK2	S325	S327F	327	Missense	proximal	2	no	13.440	13.624	PhosphoSitePlus;EPSD	COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	Q15788	NCOA1	P24941	CDK2	S325	P326L	326	Missense	proximal	1	no	13.440	3.619	PhosphoSitePlus;EPSD	COSMIC	8.148	Loss
CMGC_CDK_CDK2_CDK2_ST	Q15788	NCOA1	P24941	CDK2	S372	P373S	373	Missense	proximal	1	no	8.365	-2.901	EPSD	COSMIC;GDSC;CCLE	8.148	Loss
CMGC_CDK_CDK2_CDK2_ST	Q15788	NCOA1	P24941	CDK2	S372	D365N	365	Missense	distal	-7	no	8.365	8.042	EPSD	COSMIC	8.148	Loss
CMGC_CDK_CDK2_CDK2_ST	Q15788	NCOA1	P24941	CDK2	S372	S372G	372	Missense	central	0	yes	8.365	0.000	EPSD	COSMIC	8.148	Loss
CMGC_CDK_CDK2_CDK2_ST	Q15788	NCOA1	P24941	CDK2	S517	S523G	523	Missense	distal	6	no	14.452	14.439	EPSD	COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	Q15788	NCOA1	P24941	CDK2	S558	S557I	557	Missense	proximal	-1	no	10.355	10.809	EPSD	COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	Q15788	NCOA1	P24941	CDK2	S603	D604G	604	Missense	proximal	1	no	8.801	9.732	EPSD	COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	Q15788	NCOA1	P24941	CDK2	S698	R692W	692	Missense	distal	-6	no	11.902	11.908	EPSD	COSMIC;GDSC;CCLE	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	Q15788	NCOA1	P24941	CDK2	T789	P790S	790	Missense	proximal	1	no	14.593	3.327	EPSD;PhosphoSitePlus	COSMIC	8.148	Loss
CMGC_CDK_CDK2_CDK2_ST	Q15788	NCOA1	P24941	CDK2	T979	T979M	979	Missense	central	0	yes	12.496	0.000	EPSD;PhosphoSitePlus	COSMIC;GDSC;CCLE	8.148	Loss
CMGC_CDK_CDK2_CDK2_ST	Q15788	NCOA1	P24941	CDK2	T979	E986K	986	Missense	distal	7	no	12.496	12.165	EPSD;PhosphoSitePlus	COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	Q15788	NCOA1	P24941	CDK2	T979	M984K	984	Missense	distal	5	no	12.496	12.134	EPSD;PhosphoSitePlus	COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	Q15788	NCOA1	P24941	CDK2	S997	S999T	999	Missense	proximal	2	no	11.843	11.599	EPSD;PhosphoSitePlus	COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	Q15788	NCOA1	P24941	CDK2	S997	Y995H	995	Missense	proximal	-2	no	11.843	11.397	EPSD;PhosphoSitePlus	COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	Q15788	NCOA1	P24941	CDK2	S997	Y991N	991	Missense	distal	-6	no	11.843	11.842	EPSD;PhosphoSitePlus	COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	Q15788	NCOA1	P24941	CDK2	S997	P994S	994	Missense	distal	-3	no	11.843	11.938	EPSD;PhosphoSitePlus	COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	Q15788	NCOA1	P24941	CDK2	S999	Y995H	995	Missense	distal	-4	no	13.074	12.005	EPSD	COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	Q15788	NCOA1	P24941	CDK2	S999	P994S	994	Missense	distal	-5	no	13.074	13.030	EPSD	COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	Q15788	NCOA1	P24941	CDK2	S1006	R1013S	1013	Missense	distal	7	no	13.477	12.835	EPSD;PhosphoSitePlus	COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	Q15788	NCOA1	P24941	CDK2	S1006	S999T	999	Missense	distal	-7	no	13.477	13.654	EPSD;PhosphoSitePlus	COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	Q15788	NCOA1	P24941	CDK2	T1026	T1020A	1020	Missense	distal	-6	no	13.395	13.394	EPSD;PhosphoSitePlus	COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	Q15788	NCOA1	P24941	CDK2	T1026	M1021T	1021	Missense	distal	-5	no	13.395	13.287	EPSD;PhosphoSitePlus	COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	Q15788	NCOA1	P24941	CDK2	T1026	R1029G	1029	Missense	distal	3	no	13.395	11.576	EPSD;PhosphoSitePlus	COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	Q15788	NCOA1	P24941	CDK2	S1033	R1029G	1029	Missense	distal	-4	no	15.362	15.287	EPSD;PhosphoSitePlus	COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	Q15788	NCOA1	P24941	CDK2	T1099	N1105S	1105	Missense	distal	6	no	11.778	11.776	EPSD	COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	Q15788	NCOA1	P24941	CDK2	T1099	P1100L	1100	Missense	proximal	1	no	11.778	1.958	EPSD	COSMIC	8.148	Loss
CMGC_CDK_CDK2_CDK2_ST	Q15788	NCOA1	P24941	CDK2	T1099	P1100T	1100	Missense	proximal	1	no	11.778	1.821	EPSD	COSMIC	8.148	Loss
CMGC_CDK_CDK2_CDK2_ST	Q15788	NCOA1	P24941	CDK2	T1099	P1100H	1100	Missense	proximal	1	no	11.778	5.020	EPSD	COSMIC	8.148	Loss
CMGC_CDK_CDK2_CDK2_ST	Q15788	NCOA1	P24941	CDK2	T1179	T1175K	1175	Missense	distal	-4	no	13.578	13.330	EPSD;PhosphoSitePlus	COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	Q15788	NCOA1	P24941	CDK2	T1179	T1175M	1175	Missense	distal	-4	no	13.578	12.663	EPSD;PhosphoSitePlus	COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	Q15788	NCOA1	P24941	CDK2	S1250	P1251H	1251	Missense	proximal	1	no	10.963	4.204	EPSD;PhosphoSitePlus	COSMIC	8.148	Loss
CMGC_CDK_CDK2_CDK2_ST	Q15788	NCOA1	P24941	CDK2	S1250	P1251L	1251	Missense	proximal	1	no	10.963	1.142	EPSD;PhosphoSitePlus	COSMIC	8.148	Loss
CMGC_CDK_CDK2_CDK2_ST	Q15788	NCOA1	P24941	CDK2	S1250	N1244S	1244	Missense	distal	-6	no	10.963	10.962	EPSD;PhosphoSitePlus	COSMIC;GDSC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	Q15788	NCOA1	P24941	CDK2	T1271	P1272S	1272	Missense	proximal	1	no	10.137	-1.129	EPSD;PhosphoSitePlus	COSMIC	8.148	Loss
CMGC_CDK_CDK2_CDK2_ST	Q15788	NCOA1	P24941	CDK2	S1279	P1272S	1272	Missense	distal	-7	no	15.314	15.134	EPSD;PhosphoSitePlus	COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	P23771	GATA3	P24941	CDK2	S110	P111S	111	Missense	proximal	1	no	11.995	0.729	EPSD	COSMIC	8.148	Loss
CMGC_CDK_CDK2_CDK2_ST	P23771	GATA3	P24941	CDK2	S110	S110F	110	Missense	central	0	yes	11.995	0.000	EPSD	COSMIC	8.148	Loss
CMGC_CDK_CDK2_CDK2_ST	P23771	GATA3	P24941	CDK2	S110	P111H	111	Missense	proximal	1	no	11.995	5.236	EPSD	COSMIC	8.148	Loss
CMGC_CDK_CDK2_CDK2_ST	P23771	GATA3	P24941	CDK2	S110	T108I	108	Missense	proximal	-2	no	11.995	11.874	EPSD	COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	P23771	GATA3	P24941	CDK2	S110	H107Y	107	Missense	distal	-3	no	11.995	11.963	EPSD	COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	P23771	GATA3	P24941	CDK2	S110	L114I	114	Missense	distal	4	no	11.995	11.854	EPSD	COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	P23771	GATA3	P24941	CDK2	S115	P111S	111	Missense	distal	-4	no	12.062	12.416	EPSD	COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	P23771	GATA3	P24941	CDK2	S115	S110F	110	Missense	distal	-5	no	12.062	12.178	EPSD	COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	P23771	GATA3	P24941	CDK2	S115	P111H	111	Missense	distal	-4	no	12.062	11.458	EPSD	COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	P23771	GATA3	P24941	CDK2	S115	T108I	108	Missense	distal	-7	no	12.062	12.259	EPSD	COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	P23771	GATA3	P24941	CDK2	S115	S121F	121	Missense	distal	6	no	12.062	12.042	EPSD	COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	P23771	GATA3	P24941	CDK2	S115	L114I	114	Missense	proximal	-1	no	12.062	12.224	EPSD	COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	P23771	GATA3	P24941	CDK2	T156	P158L	158	Missense	proximal	2	no	16.652	16.545	PhosphoSitePlus	COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	P23771	GATA3	P24941	CDK2	T156	S162F	162	Missense	distal	6	no	16.652	16.633	PhosphoSitePlus	COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	P23771	GATA3	P24941	CDK2	T156	P163Q	163	Missense	distal	7	no	16.652	16.497	PhosphoSitePlus	COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	P23771	GATA3	P24941	CDK2	T156	T156P	156	Missense	central	0	yes	16.652	0.000	PhosphoSitePlus	COSMIC;GDSC	8.148	Loss
CMGC_CDK_CDK2_CDK2_ST	P23771	GATA3	P24941	CDK2	T156	P163S	163	Missense	distal	7	no	16.652	16.500	PhosphoSitePlus	COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	P23771	GATA3	P24941	CDK2	S162	P158L	158	Missense	distal	-4	no	12.164	12.106	EPSD	COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	P23771	GATA3	P24941	CDK2	S162	S162F	162	Missense	central	0	yes	12.164	0.000	EPSD	COSMIC	8.148	Loss
CMGC_CDK_CDK2_CDK2_ST	P23771	GATA3	P24941	CDK2	S162	S166A	166	Missense	distal	4	no	12.164	12.191	EPSD	COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	P23771	GATA3	P24941	CDK2	S162	P163Q	163	Missense	proximal	1	no	12.164	4.253	EPSD	COSMIC	8.148	Loss
CMGC_CDK_CDK2_CDK2_ST	P23771	GATA3	P24941	CDK2	S162	T156P	156	Missense	distal	-6	no	12.164	12.165	EPSD	COSMIC;GDSC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	P23771	GATA3	P24941	CDK2	S162	P163S	163	Missense	proximal	1	no	12.164	0.898	EPSD	COSMIC	8.148	Loss
CMGC_CDK_CDK2_CDK2_ST	P23771	GATA3	P24941	CDK2	T169	S162F	162	Missense	distal	-7	no	13.814	14.365	EPSD	COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	P23771	GATA3	P24941	CDK2	T169	S166A	166	Missense	distal	-3	no	13.814	13.660	EPSD	COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	P23771	GATA3	P24941	CDK2	T169	P163Q	163	Missense	distal	-6	no	13.814	13.817	EPSD	COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	P23771	GATA3	P24941	CDK2	T169	S172L	172	Missense	distal	3	no	13.814	13.396	EPSD	COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	P23771	GATA3	P24941	CDK2	T169	P163S	163	Missense	distal	-6	no	13.814	13.813	EPSD	COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	P23771	GATA3	P24941	CDK2	T169	A173T	173	Missense	distal	4	no	13.814	14.057	EPSD	COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	P23771	GATA3	P24941	CDK2	T169	G174S	174	Missense	distal	5	no	13.814	13.586	EPSD	COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	P23771	GATA3	P24941	CDK2	T169	A176G	176	Missense	distal	7	no	13.814	14.099	EPSD	COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	P23771	GATA3	P24941	CDK2	S243	G248R	248	Missense	distal	5	no	12.847	12.826	EPSD	COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	P23771	GATA3	P24941	CDK2	S243	G241F	241	Missense	proximal	-2	no	12.847	12.476	EPSD	COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	P23771	GATA3	P24941	CDK2	S243	S243Y	243	Missense	central	0	yes	12.847	0.000	EPSD	COSMIC	8.148	Loss
CMGC_CDK_CDK2_CDK2_ST	P23771	GATA3	P24941	CDK2	S243	S238R	238	Missense	distal	-5	no	12.847	12.938	EPSD	COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	P23771	GATA3	P24941	CDK2	S243	G246A	246	Missense	distal	3	no	12.847	12.436	EPSD	COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	P23771	GATA3	P24941	CDK2	T271	R276W	276	Missense	distal	5	no	12.414	12.580	EPSD	COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	P23771	GATA3	P24941	CDK2	T271	A268P	268	Missense	distal	-3	no	12.414	12.472	EPSD	COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	Q15554	TERF2	P24941	CDK2	S53	S50R	50	Missense	distal	-3	no	9.258	9.351	EPSD	COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	Q15554	TERF2	P24941	CDK2	T169	E165K	165	Missense	distal	-4	no	12.341	12.030	EPSD	COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	Q15554	TERF2	P24941	CDK2	T169	E165D	165	Missense	distal	-4	no	12.341	12.638	EPSD	COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	Q15554	TERF2	P24941	CDK2	T169	L168R	168	Missense	proximal	-1	no	12.341	13.091	EPSD	COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	Q15554	TERF2	P24941	CDK2	S365	L368P	368	Missense	distal	3	no	14.668	15.051	PhosphoSitePlus	COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	Q9UGP5	POLL	P24941	CDK2	S167	T173A	173	Missense	distal	6	no	13.863	13.851	EPSD;PhosphoSitePlus	COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	Q9UGP5	POLL	P24941	CDK2	S167	T173P	173	Missense	distal	6	no	13.863	13.855	EPSD;PhosphoSitePlus	COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	Q9UGP5	POLL	P24941	CDK2	S167	L162M	162	Missense	distal	-5	no	13.863	13.958	EPSD;PhosphoSitePlus	COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	Q9UGP5	POLL	P24941	CDK2	S177	T173A	173	Missense	distal	-4	no	14.528	14.303	PhosphoSitePlus;EPSD	COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	Q9UGP5	POLL	P24941	CDK2	S177	T173P	173	Missense	distal	-4	no	14.528	14.362	PhosphoSitePlus;EPSD	COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	Q9UGP5	POLL	P24941	CDK2	S177	P175S	175	Missense	proximal	-2	no	14.528	13.877	PhosphoSitePlus;EPSD	COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	Q9UGP5	POLL	P24941	CDK2	T553	D558N	558	Missense	distal	5	no	15.305	15.234	EPSD;PhosphoSitePlus	COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	Q9UGP5	POLL	P24941	CDK2	T553	P552L	552	Missense	proximal	-1	no	15.305	15.125	EPSD;PhosphoSitePlus	COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	O94761	RECQL4	P24941	CDK2	S89	R96Q	96	Missense	distal	7	no	15.429	14.785	EPSD;PhosphoSitePlus	COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	O94761	RECQL4	P24941	CDK2	S89	K88N	88	Missense	proximal	-1	no	15.429	15.456	EPSD;PhosphoSitePlus	COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	O94761	RECQL4	P24941	CDK2	S89	P94L	94	Missense	distal	5	no	15.429	15.469	EPSD;PhosphoSitePlus	COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	O94761	RECQL4	P24941	CDK2	T93	R96Q	96	Missense	distal	3	no	17.099	15.355	EPSD	COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	O94761	RECQL4	P24941	CDK2	T93	K88N	88	Missense	distal	-5	no	17.099	17.115	EPSD	COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	O94761	RECQL4	P24941	CDK2	T93	P94L	94	Missense	proximal	1	no	17.099	7.278	EPSD	COSMIC	8.148	Loss
CMGC_CDK_CDK2_CDK2_ST	O94761	RECQL4	P24941	CDK2	T93	G100E	100	Missense	distal	7	no	17.099	16.473	EPSD	COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	O94761	RECQL4	P24941	CDK2	T139	R132T	132	Missense	distal	-7	no	13.183	12.836	EPSD	COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	O94761	RECQL4	P24941	CDK2	T139	R132K	132	Missense	distal	-7	no	13.183	12.792	EPSD	COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	O94761	RECQL4	P24941	CDK2	T139	A137T	137	Missense	proximal	-2	no	13.183	13.133	EPSD	COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	O94761	RECQL4	P24941	CDK2	S251	G258R	258	Missense	distal	7	no	14.684	14.504	PhosphoSitePlus;EPSD	COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	O94761	RECQL4	P24941	CDK2	S251	R248H	248	Missense	distal	-3	no	14.684	14.642	PhosphoSitePlus;EPSD	COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	O94761	RECQL4	P24941	CDK2	S251	S251I	251	Missense	central	0	yes	14.684	0.000	PhosphoSitePlus;EPSD	COSMIC	8.148	Loss
CMGC_CDK_CDK2_CDK2_ST	O94761	RECQL4	P24941	CDK2	S251	S256G	256	Missense	distal	5	no	14.684	14.912	PhosphoSitePlus;EPSD	COSMIC;GDSC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	O94761	RECQL4	P24941	CDK2	S251	E244K	244	Missense	distal	-7	no	14.684	14.547	PhosphoSitePlus;EPSD	COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	O94761	RECQL4	P24941	CDK2	S323	G321R	321	Missense	proximal	-2	no	13.471	12.977	EPSD	COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	O94761	RECQL4	P24941	CDK2	S323	P324S	324	Missense	proximal	1	no	13.471	2.205	EPSD	COSMIC	8.148	Loss
CMGC_CDK_CDK2_CDK2_ST	O94761	RECQL4	P24941	CDK2	S323	P324L	324	Missense	proximal	1	no	13.471	3.650	EPSD	COSMIC	8.148	Loss
CMGC_CDK_CDK2_CDK2_ST	O94761	RECQL4	P24941	CDK2	S326	G331E	331	Missense	distal	5	no	11.151	11.104	EPSD	COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	O94761	RECQL4	P24941	CDK2	S326	G321R	321	Missense	distal	-5	no	11.151	11.119	EPSD	COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	O94761	RECQL4	P24941	CDK2	S326	P324S	324	Missense	proximal	-2	no	11.151	10.500	EPSD	COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	O94761	RECQL4	P24941	CDK2	S326	P324L	324	Missense	proximal	-2	no	11.151	10.927	EPSD	COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	O94761	RECQL4	P24941	CDK2	S732	R735C	735	Missense	distal	3	no	8.754	2.390	EPSD	COSMIC	8.148	Loss
CMGC_CDK_CDK2_CDK2_ST	O94761	RECQL4	P24941	CDK2	S732	V729I	729	Missense	distal	-3	no	8.754	8.631	EPSD	COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	O94761	RECQL4	P24941	CDK2	S732	A727G	727	Missense	distal	-5	no	8.754	8.809	EPSD	COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	O94761	RECQL4	P24941	CDK2	S732	P730S	730	Missense	proximal	-2	no	8.754	8.103	EPSD	COSMIC	8.148	Loss
CMGC_CDK_CDK2_CDK2_ST	Q9NSV4	DIAPH3	P24941	CDK2	T19	P22L	22	Missense	distal	3	no	14.980	14.596	PhosphoSitePlus	COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	Q9NSV4	DIAPH3	P24941	CDK2	S48	G49D	49	Missense	proximal	1	no	8.475	7.543	EPSD	COSMIC	8.148	Loss
CMGC_CDK_CDK2_CDK2_ST	Q9NSV4	DIAPH3	P24941	CDK2	S175	E182D	182	Missense	distal	7	no	14.160	14.802	EPSD	COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	Q9NSV4	DIAPH3	P24941	CDK2	S175	S171N	171	Missense	distal	-4	no	14.160	13.944	EPSD	COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	Q9NSV4	DIAPH3	P24941	CDK2	S607	P600L	600	Missense	distal	-7	no	8.173	8.179	EPSD	COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	Q9NSV4	DIAPH3	P24941	CDK2	S607	P600H	600	Missense	distal	-7	no	8.173	8.296	EPSD	COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	Q9NSV4	DIAPH3	P24941	CDK2	S624	P631H	631	Missense	distal	7	no	14.198	14.330	EPSD	COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	Q9NSV4	DIAPH3	P24941	CDK2	S624	P631S	631	Missense	distal	7	no	14.198	14.046	EPSD	COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	Q9NSV4	DIAPH3	P24941	CDK2	S624	P625A	625	Missense	proximal	1	no	14.198	-0.205	EPSD	COSMIC	8.148	Loss
CMGC_CDK_CDK2_CDK2_ST	Q9NSV4	DIAPH3	P24941	CDK2	S624	I629T	629	Missense	distal	5	no	14.198	14.080	EPSD	COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	Q9NSV4	DIAPH3	P24941	CDK2	S1093	S1096Y	1096	Missense	distal	3	no	14.173	13.394	EPSD	COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	Q9NSV4	DIAPH3	P24941	CDK2	S1093	M1095V	1095	Missense	proximal	2	no	14.173	14.085	EPSD	COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	Q9NSV4	DIAPH3	P24941	CDK2	S1096	S1096Y	1096	Missense	central	0	yes	10.135	0.000	EPSD	COSMIC	8.148	Loss
CMGC_CDK_CDK2_CDK2_ST	Q9NSV4	DIAPH3	P24941	CDK2	S1096	M1095V	1095	Missense	proximal	-1	no	10.135	9.042	EPSD	COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	Q9NSV4	DIAPH3	P24941	CDK2	S1096	L1101F	1101	Missense	distal	5	no	10.135	10.313	EPSD	COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	Q9NSV4	DIAPH3	P24941	CDK2	T1130	K1134N	1134	Missense	distal	4	no	13.879	13.458	EPSD	COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	Q9NSV4	DIAPH3	P24941	CDK2	T1130	I1123M	1123	Missense	distal	-7	no	13.879	14.186	EPSD	COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	P28324	ELK4	P24941	CDK2	S230	T227I	227	Missense	distal	-3	no	12.406	12.465	EPSD	COSMIC;GDSC;CCLE	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	P28324	ELK4	P24941	CDK2	S230	Q223K	223	Missense	distal	-7	no	12.406	12.401	EPSD	COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	P28324	ELK4	P24941	CDK2	S230	S230F	230	Missense	central	0	yes	12.406	0.000	EPSD	COSMIC	8.148	Loss
CMGC_CDK_CDK2_CDK2_ST	P28324	ELK4	P24941	CDK2	S381	P382H	382	Missense	proximal	1	no	14.446	7.688	EPSD	COSMIC	8.148	Loss
CMGC_CDK_CDK2_CDK2_ST	P28324	ELK4	P24941	CDK2	S381	L380V	380	Missense	proximal	-1	no	14.446	14.583	EPSD	COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	P28324	ELK4	P24941	CDK2	S387	P382H	382	Missense	distal	-5	no	15.345	15.392	PhosphoSitePlus;EPSD	COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	P28324	ELK4	P24941	CDK2	S387	L380V	380	Missense	distal	-7	no	15.345	15.360	PhosphoSitePlus;EPSD	COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	P28324	ELK4	P24941	CDK2	T420	D427N	427	Missense	distal	7	no	13.564	12.784	EPSD	COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	P28324	ELK4	P24941	CDK2	T420	F424L	424	Missense	distal	4	no	13.564	13.858	EPSD	COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	P28324	ELK4	P24941	CDK2	T420	G414W	414	Missense	distal	-6	no	13.564	13.569	EPSD	COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	P28324	ELK4	P24941	CDK2	T420	P421F	421	Missense	proximal	1	no	13.564	-1.246	EPSD	COSMIC	8.148	Loss
CMGC_CDK_CDK2_CDK2_ST	P28324	ELK4	P24941	CDK2	S425	K430N	430	Missense	distal	5	no	16.192	16.349	EPSD	COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	P28324	ELK4	P24941	CDK2	S425	D427N	427	Missense	proximal	2	no	16.192	16.124	EPSD	COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	P28324	ELK4	P24941	CDK2	S425	F424L	424	Missense	proximal	-1	no	16.192	15.227	EPSD	COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	P28324	ELK4	P24941	CDK2	S425	L428P	428	Missense	distal	3	no	16.192	16.575	EPSD	COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	P28324	ELK4	P24941	CDK2	S425	P421F	421	Missense	distal	-4	no	16.192	15.584	EPSD	COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	P03372	ESR1	P24941	CDK2	S104	F97L	97	Missense	distal	-7	no	16.821	16.455	EPSD;PhosphoSitePlus	COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	P03372	ESR1	P24941	CDK2	S104	M109T	109	Missense	distal	5	no	16.821	16.487	EPSD;PhosphoSitePlus	COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	P03372	ESR1	P24941	CDK2	S106	P113L	113	Missense	distal	7	no	12.768	12.798	EPSD;PhosphoSitePlus	COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	P03372	ESR1	P24941	CDK2	S106	P113Q	113	Missense	distal	7	no	12.768	12.613	EPSD;PhosphoSitePlus	COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	P03372	ESR1	P24941	CDK2	S106	H112L	112	Missense	distal	6	no	12.768	12.774	EPSD;PhosphoSitePlus	COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	P03372	ESR1	P24941	CDK2	S106	M109T	109	Missense	distal	3	no	12.768	12.894	EPSD;PhosphoSitePlus	COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	P03372	ESR1	P24941	CDK2	S118	P113L	113	Missense	distal	-5	no	12.997	13.009	PhosphoSitePlus;EPSD	COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	P03372	ESR1	P24941	CDK2	S118	L117Q	117	Missense	proximal	-1	no	12.997	12.869	PhosphoSitePlus;EPSD	COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	P03372	ESR1	P24941	CDK2	S118	H112L	112	Missense	distal	-6	no	12.997	12.993	PhosphoSitePlus;EPSD	COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	P03372	ESR1	P24941	CDK2	S118	S118P	118	Missense	central	0	yes	12.997	0.000	PhosphoSitePlus;EPSD	COSMIC	8.148	Loss
CMGC_CDK_CDK2_CDK2_ST	P03372	ESR1	P24941	CDK2	S294	K299R	299	Missense	distal	5	no	12.927	13.088	EPSD;PhosphoSitePlus	COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	P03372	ESR1	P24941	CDK2	S294	P295L	295	Missense	proximal	1	no	12.927	3.107	EPSD;PhosphoSitePlus	COSMIC	8.148	Loss
CMGC_CDK_CDK2_CDK2_ST	P03372	ESR1	P24941	CDK2	S294	R300C	300	Missense	distal	6	no	12.927	12.930	EPSD;PhosphoSitePlus	COSMIC;CCLE	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	P03372	ESR1	P24941	CDK2	S294	L296P	296	Missense	proximal	2	no	12.927	13.034	EPSD;PhosphoSitePlus	COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	P03372	ESR1	P24941	CDK2	S294	N290K	290	Missense	distal	-4	no	12.927	12.708	EPSD;PhosphoSitePlus	COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	P03372	ESR1	P24941	CDK2	S294	S294R	294	Missense	central	0	yes	12.927	0.000	EPSD;PhosphoSitePlus	COSMIC	8.148	Loss
CMGC_CDK_CDK2_CDK2_ST	P03372	ESR1	P24941	CDK2	S294	A288T	288	Missense	distal	-6	no	12.927	12.928	EPSD;PhosphoSitePlus	COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	P03372	ESR1	P24941	CDK2	S294	R287H	287	Missense	distal	-7	no	12.927	12.707	EPSD;PhosphoSitePlus	COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	P03372	ESR1	P24941	CDK2	S294	R287C	287	Missense	distal	-7	no	12.927	12.855	EPSD;PhosphoSitePlus	COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	Q12778	FOXO1	P24941	CDK2	T231	S234R	234	Missense	distal	3	no	7.356	9.041	EPSD	COSMIC	8.148	Gain
CMGC_CDK_CDK2_CDK2_ST	Q12778	FOXO1	P24941	CDK2	S249	G243S	243	Missense	distal	-6	no	12.577	12.573	PhosphoSitePlus	COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	Q12778	FOXO1	P24941	CDK2	S249	G243V	243	Missense	distal	-6	no	12.577	12.576	PhosphoSitePlus	COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	Q12778	FOXO1	P24941	CDK2	S279	Q278L	278	Missense	proximal	-1	no	8.190	8.318	EPSD	COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	Q12778	FOXO1	P24941	CDK2	S279	L277F	277	Missense	proximal	-2	no	8.190	7.301	EPSD	COSMIC	8.148	Loss
CMGC_CDK_CDK2_CDK2_ST	Q12778	FOXO1	P24941	CDK2	S287	S287N	287	Missense	central	0	yes	15.718	0.000	EPSD	COSMIC	8.148	Loss
CMGC_CDK_CDK2_CDK2_ST	Q12778	FOXO1	P24941	CDK2	S290	S287N	287	Missense	distal	-3	no	8.968	8.893	EPSD	COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	Q12778	FOXO1	P24941	CDK2	S298	H302Y	302	Missense	distal	4	no	12.278	12.715	EPSD	COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	Q12778	FOXO1	P24941	CDK2	S383	S382L	382	Missense	proximal	-1	no	15.642	15.933	EPSD	COSMIC;GDSC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	Q12778	FOXO1	P24941	CDK2	S383	L380I	380	Missense	distal	-3	no	15.642	15.733	EPSD	COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	Q12778	FOXO1	P24941	CDK2	S383	S390L	390	Missense	distal	7	no	15.642	15.824	EPSD	COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	Q12778	FOXO1	P24941	CDK2	S383	S386P	386	Missense	distal	3	no	15.642	15.608	EPSD	COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	Q12778	FOXO1	P24941	CDK2	S394	S393Y	393	Missense	proximal	-1	no	13.914	14.824	EPSD	COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	Q12778	FOXO1	P24941	CDK2	S394	S390L	390	Missense	distal	-4	no	13.914	13.502	EPSD	COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	Q12778	FOXO1	P24941	CDK2	T402	Y405C	405	Missense	distal	3	no	11.030	7.130	EPSD	COSMIC	8.148	Loss
CMGC_CDK_CDK2_CDK2_ST	Q12778	FOXO1	P24941	CDK2	S416	P417S	417	Missense	proximal	1	no	14.544	3.278	EPSD	COSMIC	8.148	Loss
CMGC_CDK_CDK2_CDK2_ST	Q12778	FOXO1	P24941	CDK2	S418	P417S	417	Missense	proximal	-1	no	13.514	13.043	EPSD	COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	Q12778	FOXO1	P24941	CDK2	S432	P438H	438	Missense	distal	6	no	13.610	13.605	EPSD	COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	Q12778	FOXO1	P24941	CDK2	S432	S432N	432	Missense	central	0	yes	13.610	0.000	EPSD	COSMIC	8.148	Loss
CMGC_CDK_CDK2_CDK2_ST	Q12778	FOXO1	P24941	CDK2	S432	I439V	439	Missense	distal	7	no	13.610	13.811	EPSD	COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	Q12778	FOXO1	P24941	CDK2	S432	G427V	427	Missense	distal	-5	no	13.610	13.561	EPSD	COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	Q12778	FOXO1	P24941	CDK2	S470	D469A	469	Missense	proximal	-1	no	15.813	14.787	EPSD	COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	Q12778	FOXO1	P24941	CDK2	S470	K463N	463	Missense	distal	-7	no	15.813	15.779	EPSD	COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	Q12778	FOXO1	P24941	CDK2	S470	N474D	474	Missense	distal	4	no	15.813	15.768	EPSD	COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	Q12778	FOXO1	P24941	CDK2	T478	P482A	482	Missense	distal	4	no	13.501	13.541	EPSD	COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	Q12778	FOXO1	P24941	CDK2	T478	P482H	482	Missense	distal	4	no	13.501	13.263	EPSD	COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	Q12778	FOXO1	P24941	CDK2	T478	P479S	479	Missense	proximal	1	no	13.501	2.235	EPSD	COSMIC	8.148	Loss
CMGC_CDK_CDK2_CDK2_ST	Q12778	FOXO1	P24941	CDK2	T478	N474D	474	Missense	distal	-4	no	13.501	13.890	EPSD	COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	Q12778	FOXO1	P24941	CDK2	T649	S644I	644	Missense	distal	-5	no	8.347	8.430	EPSD	COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	P12268	IMPDH2	P24941	CDK2	S122	R126H	126	Missense	distal	4	no	13.332	13.215	PhosphoSitePlus	COSMIC;CCLE	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	O75533	SF3B1	P24941	CDK2	T61	E64K	64	Missense	distal	3	no	6.109	8.195	EPSD	COSMIC	8.148	Gain
CMGC_CDK_CDK2_CDK2_ST	O75533	SF3B1	P24941	CDK2	S129	F136L	136	Missense	distal	7	no	18.222	17.550	EPSD	COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	O75533	SF3B1	P24941	CDK2	S129	R132H	132	Missense	distal	3	no	18.222	17.525	EPSD	COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	O75533	SF3B1	P24941	CDK2	T142	F136L	136	Missense	distal	-6	no	14.904	14.900	EPSD;PhosphoSitePlus	COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	O75533	SF3B1	P24941	CDK2	T142	M147I	147	Missense	distal	5	no	14.904	14.689	EPSD;PhosphoSitePlus	COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	O75533	SF3B1	P24941	CDK2	T142	D144N	144	Missense	proximal	2	no	14.904	14.837	EPSD;PhosphoSitePlus	COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	O75533	SF3B1	P24941	CDK2	T142	P145R	145	Missense	distal	3	no	14.904	16.623	EPSD;PhosphoSitePlus	COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	O75533	SF3B1	P24941	CDK2	T223	P224S	224	Missense	proximal	1	no	16.464	5.198	EPSD	COSMIC	8.148	Loss
CMGC_CDK_CDK2_CDK2_ST	O75533	SF3B1	P24941	CDK2	T223	Q220R	220	Missense	distal	-3	no	16.464	16.594	EPSD	COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	O75533	SF3B1	P24941	CDK2	T223	S229Y	229	Missense	distal	6	no	16.464	16.455	EPSD	COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	O75533	SF3B1	P24941	CDK2	T223	D219E	219	Missense	distal	-4	no	16.464	16.167	EPSD	COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	O75533	SF3B1	P24941	CDK2	T227	P224S	224	Missense	distal	-3	no	13.378	13.473	EPSD	COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	O75533	SF3B1	P24941	CDK2	T227	Q220R	220	Missense	distal	-7	no	13.378	13.764	EPSD	COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	O75533	SF3B1	P24941	CDK2	T227	S229Y	229	Missense	proximal	2	no	13.378	13.369	EPSD	COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	O75533	SF3B1	P24941	CDK2	T235	R238H	238	Missense	distal	3	no	15.794	15.098	EPSD	COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	O75533	SF3B1	P24941	CDK2	T235	S229Y	229	Missense	distal	-6	no	15.794	15.795	EPSD	COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	O75533	SF3B1	P24941	CDK2	T235	R238C	238	Missense	distal	3	no	15.794	9.430	EPSD	COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	O75533	SF3B1	P24941	CDK2	T244	R238H	238	Missense	distal	-6	no	12.901	12.903	EPSD;PhosphoSitePlus	COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	O75533	SF3B1	P24941	CDK2	T244	E243K	243	Missense	proximal	-1	no	12.901	12.016	EPSD;PhosphoSitePlus	COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	O75533	SF3B1	P24941	CDK2	T244	R238C	238	Missense	distal	-6	no	12.901	12.904	EPSD;PhosphoSitePlus	COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	O75533	SF3B1	P24941	CDK2	T248	E243K	243	Missense	distal	-5	no	14.377	14.342	EPSD;PhosphoSitePlus	COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	O75533	SF3B1	P24941	CDK2	T248	I253V	253	Missense	distal	5	no	14.377	14.251	EPSD;PhosphoSitePlus	COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	O75533	SF3B1	P24941	CDK2	T257	S259R	259	Missense	proximal	2	no	15.238	15.330	EPSD	COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	O75533	SF3B1	P24941	CDK2	T257	P256L	256	Missense	proximal	-1	no	15.238	15.058	EPSD	COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	O75533	SF3B1	P24941	CDK2	T257	I253V	253	Missense	distal	-4	no	15.238	15.340	EPSD	COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	O75533	SF3B1	P24941	CDK2	T257	A263T	263	Missense	distal	6	no	15.238	15.250	EPSD	COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	O75533	SF3B1	P24941	CDK2	S259	S259R	259	Missense	central	0	yes	8.642	0.000	EPSD	COSMIC	8.148	Loss
CMGC_CDK_CDK2_CDK2_ST	O75533	SF3B1	P24941	CDK2	S259	P256L	256	Missense	distal	-3	no	8.642	8.571	EPSD	COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	O75533	SF3B1	P24941	CDK2	S259	A263T	263	Missense	distal	4	no	8.642	8.885	EPSD	COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	O75533	SF3B1	P24941	CDK2	T261	S259R	259	Missense	proximal	-2	no	14.208	13.624	EPSD	COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	O75533	SF3B1	P24941	CDK2	T261	P256L	256	Missense	distal	-5	no	14.208	14.220	EPSD	COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	O75533	SF3B1	P24941	CDK2	T261	A263T	263	Missense	proximal	2	no	14.208	14.006	EPSD	COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	O75533	SF3B1	P24941	CDK2	T267	G271D	271	Missense	distal	4	no	15.272	15.327	EPSD	COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	O75533	SF3B1	P24941	CDK2	T267	A263T	263	Missense	distal	-4	no	15.272	15.497	EPSD	COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	O75533	SF3B1	P24941	CDK2	T273	A277V	277	Missense	distal	4	no	16.321	16.509	EPSD	COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	O75533	SF3B1	P24941	CDK2	T273	G271D	271	Missense	proximal	-2	no	16.321	16.929	EPSD	COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	O75533	SF3B1	P24941	CDK2	T273	P279S	279	Missense	distal	6	no	16.321	16.323	EPSD	COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	O75533	SF3B1	P24941	CDK2	T278	A277V	277	Missense	proximal	-1	no	16.046	16.273	EPSD	COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	O75533	SF3B1	P24941	CDK2	T278	G271D	271	Missense	distal	-7	no	16.046	15.962	EPSD	COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	O75533	SF3B1	P24941	CDK2	T278	G282R	282	Missense	distal	4	no	16.046	16.045	EPSD	COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	O75533	SF3B1	P24941	CDK2	T278	P279S	279	Missense	proximal	1	no	16.046	4.780	EPSD	COSMIC	8.148	Loss
CMGC_CDK_CDK2_CDK2_ST	O75533	SF3B1	P24941	CDK2	T296	K298I	298	Missense	proximal	2	no	15.789	15.907	EPSD	COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	O75533	SF3B1	P24941	CDK2	T296	W293R	293	Missense	distal	-3	no	15.789	15.708	EPSD	COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	O75533	SF3B1	P24941	CDK2	T296	N291I	291	Missense	distal	-5	no	15.789	15.809	EPSD	COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	O75533	SF3B1	P24941	CDK2	T296	P297L	297	Missense	proximal	1	no	15.789	5.968	EPSD	COSMIC	8.148	Loss
CMGC_CDK_CDK2_CDK2_ST	O75533	SF3B1	P24941	CDK2	T296	D302E	302	Missense	distal	6	no	15.789	15.802	EPSD	COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	O75533	SF3B1	P24941	CDK2	T296	N291Y	291	Missense	distal	-5	no	15.789	15.795	EPSD	COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	O75533	SF3B1	P24941	CDK2	T303	K298I	298	Missense	distal	-5	no	15.957	15.994	EPSD	COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	O75533	SF3B1	P24941	CDK2	T303	P304L	304	Missense	proximal	1	no	15.957	6.136	EPSD	COSMIC	8.148	Loss
CMGC_CDK_CDK2_CDK2_ST	O75533	SF3B1	P24941	CDK2	T303	H306Y	306	Missense	distal	3	no	15.957	14.189	EPSD	COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	O75533	SF3B1	P24941	CDK2	T303	D302E	302	Missense	proximal	-1	no	15.957	15.986	EPSD	COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	O75533	SF3B1	P24941	CDK2	S308	P304L	304	Missense	distal	-4	no	8.909	8.851	EPSD	COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	O75533	SF3B1	P24941	CDK2	S308	E312K	312	Missense	distal	4	no	8.909	9.294	EPSD	COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	O75533	SF3B1	P24941	CDK2	S308	H306Y	306	Missense	proximal	-2	no	8.909	9.355	EPSD	COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	O75533	SF3B1	P24941	CDK2	S308	D302E	302	Missense	distal	-6	no	8.909	8.913	EPSD	COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	O75533	SF3B1	P24941	CDK2	T313	E312K	312	Missense	proximal	-1	no	17.125	16.240	EPSD;PhosphoSitePlus	COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	O75533	SF3B1	P24941	CDK2	T313	H306Y	306	Missense	distal	-7	no	17.125	17.128	EPSD;PhosphoSitePlus	COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	O75533	SF3B1	P24941	CDK2	T326	G330E	330	Missense	distal	4	no	13.836	13.973	EPSD	COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	O75533	SF3B1	P24941	CDK2	T328	G330E	330	Missense	proximal	2	no	11.537	11.516	EPSD	COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	O75533	SF3B1	P24941	CDK2	T341	G347V	347	Missense	distal	6	no	15.136	15.146	EPSD	COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	O75533	SF3B1	P24941	CDK2	S344	G347V	347	Missense	distal	3	no	8.064	8.773	EPSD	COSMIC	8.148	Gain
CMGC_CDK_CDK2_CDK2_ST	O75533	SF3B1	P24941	CDK2	T350	G347V	347	Missense	distal	-3	no	11.465	11.504	EPSD	COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	O75533	SF3B1	P24941	CDK2	T350	P355S	355	Missense	distal	5	no	11.465	11.364	EPSD	COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	O75533	SF3B1	P24941	CDK2	T350	K357M	357	Missense	distal	7	no	11.465	12.296	EPSD	COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	O75533	SF3B1	P24941	CDK2	T350	L353V	353	Missense	distal	3	no	11.465	12.457	EPSD	COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	O75533	SF3B1	P24941	CDK2	T354	G347V	347	Missense	distal	-7	no	19.286	18.981	EPSD;PhosphoSitePlus	COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	O75533	SF3B1	P24941	CDK2	T354	P355S	355	Missense	proximal	1	no	19.286	8.020	EPSD;PhosphoSitePlus	COSMIC	8.148	Loss
CMGC_CDK_CDK2_CDK2_ST	O75533	SF3B1	P24941	CDK2	T354	K357M	357	Missense	distal	3	no	19.286	16.339	EPSD;PhosphoSitePlus	COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	O75533	SF3B1	P24941	CDK2	T354	T350S	350	Missense	distal	-4	no	19.286	19.474	EPSD;PhosphoSitePlus	COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	O75533	SF3B1	P24941	CDK2	T354	L353V	353	Missense	proximal	-1	no	19.286	19.422	EPSD;PhosphoSitePlus	COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	O75533	SF3B1	P24941	CDK2	T358	P355S	355	Missense	distal	-3	no	13.094	13.189	EPSD	COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	O75533	SF3B1	P24941	CDK2	T358	K357M	357	Missense	proximal	-1	no	13.094	14.244	EPSD	COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	O75533	SF3B1	P24941	CDK2	T358	P363S	363	Missense	distal	5	no	13.094	12.993	EPSD	COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	O75533	SF3B1	P24941	CDK2	T358	A364V	364	Missense	distal	6	no	13.094	13.097	EPSD	COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	O75533	SF3B1	P24941	CDK2	T358	L353V	353	Missense	distal	-5	no	13.094	13.113	EPSD	COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	O75533	SF3B1	P24941	CDK2	T362	P355S	355	Missense	distal	-7	no	15.139	14.959	EPSD	COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	O75533	SF3B1	P24941	CDK2	T362	K357M	357	Missense	distal	-5	no	15.139	15.243	EPSD	COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	O75533	SF3B1	P24941	CDK2	T362	P363S	363	Missense	proximal	1	no	15.139	3.873	EPSD	COSMIC	8.148	Loss
CMGC_CDK_CDK2_CDK2_ST	O75533	SF3B1	P24941	CDK2	T362	M367V	367	Missense	distal	5	no	15.139	14.798	EPSD	COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	O75533	SF3B1	P24941	CDK2	T362	A364V	364	Missense	proximal	2	no	15.139	15.237	EPSD	COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	O75533	SF3B1	P24941	CDK2	T369	P363S	363	Missense	distal	-6	no	11.508	11.507	EPSD	COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	O75533	SF3B1	P24941	CDK2	T369	M367V	367	Missense	proximal	-2	no	11.508	12.943	EPSD	COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	O75533	SF3B1	P24941	CDK2	T369	P372S	372	Missense	distal	3	no	11.508	11.542	EPSD	COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	O75533	SF3B1	P24941	CDK2	T369	A364V	364	Missense	distal	-5	no	11.508	11.514	EPSD	COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	O75533	SF3B1	P24941	CDK2	T371	M367V	367	Missense	distal	-4	no	15.690	16.390	EPSD	COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	O75533	SF3B1	P24941	CDK2	T371	P372S	372	Missense	proximal	1	no	15.690	4.424	EPSD	COSMIC	8.148	Loss
CMGC_CDK_CDK2_CDK2_ST	O75533	SF3B1	P24941	CDK2	T371	A364V	364	Missense	distal	-7	no	15.690	15.545	EPSD	COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	O75533	SF3B1	P24941	CDK2	T379	P380A	380	Missense	proximal	1	no	15.663	1.260	EPSD	COSMIC	8.148	Loss
CMGC_CDK_CDK2_CDK2_ST	O75533	SF3B1	P24941	CDK2	T379	P372S	372	Missense	distal	-7	no	15.663	15.484	EPSD	COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	O75533	SF3B1	P24941	CDK2	T426	Y421F	421	Missense	distal	-5	no	17.069	17.117	EPSD;PhosphoSitePlus	COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	O75533	SF3B1	P24941	CDK2	T426	A419P	419	Missense	distal	-7	no	17.069	16.904	EPSD;PhosphoSitePlus	COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	O75533	SF3B1	P24941	CDK2	T426	V422I	422	Missense	distal	-4	no	17.069	16.966	EPSD;PhosphoSitePlus	COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	O75533	SF3B1	P24941	CDK2	S488	R495S	495	Missense	distal	7	no	14.281	13.639	EPSD	COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	O75533	SF3B1	P24941	CDK2	S488	E491G	491	Missense	distal	3	no	14.281	13.558	EPSD	COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	O75533	SF3B1	P24941	CDK2	S488	D483Y	483	Missense	distal	-5	no	14.281	14.248	EPSD	COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	O75533	SF3B1	P24941	CDK2	S488	R495I	495	Missense	distal	7	no	14.281	13.848	EPSD	COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	O75533	SF3B1	P24941	CDK2	T508	K505E	505	Missense	distal	-3	no	13.239	13.455	EPSD	COSMIC;GDSC;CCLE	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	O75533	SF3B1	P24941	CDK2	T508	K503R	503	Missense	distal	-5	no	13.239	13.283	EPSD	COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	O75533	SF3B1	P24941	CDK2	T508	L502S	502	Missense	distal	-6	no	13.239	13.238	EPSD	COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	O75533	SF3B1	P24941	CDK2	T508	N506S	506	Missense	proximal	-2	no	13.239	13.931	EPSD	COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	O75533	SF3B1	P24941	CDK2	S541	D546Y	546	Missense	distal	5	no	13.379	13.279	EPSD	COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	O75533	SF3B1	P24941	CDK2	S541	L536F	536	Missense	distal	-5	no	13.379	13.440	EPSD	COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	O75533	SF3B1	P24941	CDK2	S541	E545Q	545	Missense	distal	4	no	13.379	13.424	EPSD	COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	O75533	SF3B1	P24941	CDK2	S541	S541F	541	Missense	central	0	yes	13.379	0.000	EPSD	COSMIC	8.148	Loss
CMGC_CDK_CDK2_CDK2_ST	O75533	SF3B1	P24941	CDK2	T1170	P1171L	1171	Missense	proximal	1	no	12.782	2.962	EPSD	COSMIC	8.148	Loss
CMGC_CDK_CDK2_CDK2_ST	P62136	PPP1CA	P24941	CDK2	S177	F170C	170	Missense	distal	-7	no	12.653	12.552	EPSD	COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	P62136	PPP1CA	P24941	CDK2	S177	P178Q	178	Missense	proximal	1	no	12.653	4.741	EPSD	COSMIC	8.148	Loss
CMGC_CDK_CDK2_CDK2_ST	P62136	PPP1CA	P24941	CDK2	S177	P178L	178	Missense	proximal	1	no	12.653	2.832	EPSD	COSMIC	8.148	Loss
CMGC_CDK_CDK2_CDK2_ST	P62136	PPP1CA	P24941	CDK2	S310	Q308L	308	Missense	proximal	-2	no	8.106	8.448	EPSD	COSMIC	8.148	Gain
CMGC_CDK_CDK2_CDK2_ST	P62136	PPP1CA	P24941	CDK2	S310	G307W	307	Missense	distal	-3	no	8.106	8.272	EPSD	COSMIC	8.148	Gain
CMGC_CDK_CDK2_CDK2_ST	P62136	PPP1CA	P24941	CDK2	S310	G315W	315	Missense	distal	5	no	8.106	8.252	EPSD	COSMIC	8.148	Gain
CMGC_CDK_CDK2_CDK2_ST	P62136	PPP1CA	P24941	CDK2	T320	P321T	321	Missense	proximal	1	no	15.483	5.525	PhosphoSitePlus	COSMIC	8.148	Loss
CMGC_CDK_CDK2_CDK2_ST	P62136	PPP1CA	P24941	CDK2	T320	P322S	322	Missense	proximal	2	no	15.483	15.549	PhosphoSitePlus	COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	P62136	PPP1CA	P24941	CDK2	T320	R323H	323	Missense	distal	3	no	15.483	14.786	PhosphoSitePlus	COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	P62136	PPP1CA	P24941	CDK2	T320	A326T	326	Missense	distal	6	no	15.483	15.495	PhosphoSitePlus	COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	P62136	PPP1CA	P24941	CDK2	T320	G315W	315	Missense	distal	-5	no	15.483	15.537	PhosphoSitePlus	COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	P12272	PTHLH	P24941	CDK2	S85	H91P	91	Missense	distal	6	no	14.581	14.586	EPSD	COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	P12272	PTHLH	P24941	CDK2	S85	P80L	80	Missense	distal	-5	no	14.581	14.592	EPSD	COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	P12272	PTHLH	P24941	CDK2	S85	P80H	80	Missense	distal	-5	no	14.581	14.628	EPSD	COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	P12272	PTHLH	P24941	CDK2	T121	K127R	127	Missense	distal	6	no	16.482	16.457	PhosphoSitePlus	COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	Q99741	CDC6	P24941	CDK2	S54	R58H	58	Missense	distal	4	no	17.116	16.998	EPSD;PhosphoSitePlus	COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	Q99741	CDC6	P24941	CDK2	T67	H69R	69	Missense	proximal	2	no	11.591	11.672	EPSD	COSMIC;GDSC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	Q99741	CDC6	P24941	CDK2	T67	H69Y	69	Missense	proximal	2	no	11.591	11.572	EPSD	COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	Q99741	CDC6	P24941	CDK2	S74	H69R	69	Missense	distal	-5	no	17.009	17.008	EPSD;PhosphoSitePlus	COSMIC;GDSC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	Q99741	CDC6	P24941	CDK2	S74	H69Y	69	Missense	distal	-5	no	17.009	16.986	EPSD;PhosphoSitePlus	COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	Q99741	CDC6	P24941	CDK2	S415	E422V	422	Missense	distal	7	no	8.578	8.792	EPSD	COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	Q99741	CDC6	P24941	CDK2	S419	P426L	426	Missense	distal	7	no	14.406	14.436	EPSD	COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	Q99741	CDC6	P24941	CDK2	S419	E422V	422	Missense	distal	3	no	14.406	14.392	EPSD	COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	P55196	AFDN	P24941	CDK2	S99	H97Y	97	Missense	proximal	-2	no	8.695	9.141	EPSD	COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	P55196	AFDN	P24941	CDK2	S99	E95Q	95	Missense	distal	-4	no	8.695	8.247	EPSD	COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	P55196	AFDN	P24941	CDK2	S99	D105V	105	Missense	distal	6	no	8.695	8.709	EPSD	COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	P55196	AFDN	P24941	CDK2	S99	G100R	100	Missense	proximal	1	no	8.695	6.209	EPSD	COSMIC	8.148	Loss
CMGC_CDK_CDK2_CDK2_ST	P55196	AFDN	P24941	CDK2	S99	S99N	99	Missense	central	0	yes	8.695	0.000	EPSD	COSMIC	8.148	Loss
CMGC_CDK_CDK2_CDK2_ST	P55196	AFDN	P24941	CDK2	S373	P380L	380	Missense	distal	7	no	10.039	10.069	EPSD	COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	P55196	AFDN	P24941	CDK2	S373	T378P	378	Missense	distal	5	no	10.039	10.064	EPSD	COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	P55196	AFDN	P24941	CDK2	S377	T378P	378	Missense	proximal	1	no	6.951	16.908	EPSD	COSMIC	8.148	Gain
CMGC_CDK_CDK2_CDK2_ST	P55196	AFDN	P24941	CDK2	S391	G393E	393	Missense	proximal	2	no	14.869	14.848	EPSD	COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	P55196	AFDN	P24941	CDK2	S412	E407K	407	Missense	distal	-5	no	8.515	8.480	EPSD	COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	P55196	AFDN	P24941	CDK2	S485	S478F	478	Missense	distal	-7	no	8.442	8.993	EPSD	COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	P55196	AFDN	P24941	CDK2	S485	M482I	482	Missense	distal	-3	no	8.442	8.093	EPSD	COSMIC	8.148	Loss
CMGC_CDK_CDK2_CDK2_ST	P55196	AFDN	P24941	CDK2	S655	R659H	659	Missense	distal	4	no	12.870	12.753	EPSD	COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	P55196	AFDN	P24941	CDK2	S655	Y650C	650	Missense	distal	-5	no	12.870	12.926	EPSD	COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	P55196	AFDN	P24941	CDK2	S655	T657A	657	Missense	proximal	2	no	12.870	13.072	EPSD	COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	P55196	AFDN	P24941	CDK2	S655	P656H	656	Missense	proximal	1	no	12.870	6.112	EPSD	COSMIC	8.148	Loss
CMGC_CDK_CDK2_CDK2_ST	P55196	AFDN	P24941	CDK2	S655	Y650H	650	Missense	distal	-5	no	12.870	12.893	EPSD	COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	P55196	AFDN	P24941	CDK2	S655	H661Q	661	Missense	distal	6	no	12.870	12.881	EPSD	COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	P55196	AFDN	P24941	CDK2	S973	W977C	977	Missense	distal	4	no	12.835	12.568	EPSD	COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	P55196	AFDN	P24941	CDK2	S973	R972C	972	Missense	proximal	-1	no	12.835	12.137	EPSD	COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	P55196	AFDN	P24941	CDK2	S973	P974S	974	Missense	proximal	1	no	12.835	1.569	EPSD	COSMIC	8.148	Loss
CMGC_CDK_CDK2_CDK2_ST	P55196	AFDN	P24941	CDK2	S973	Y980C	980	Missense	distal	7	no	12.835	13.206	EPSD	COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	P55196	AFDN	P24941	CDK2	S973	R972H	972	Missense	proximal	-1	no	12.835	12.383	EPSD	COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	P55196	AFDN	P24941	CDK2	S973	P969L	969	Missense	distal	-4	no	12.835	12.776	EPSD	COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	P55196	AFDN	P24941	CDK2	T1011	L1012P	1012	Missense	proximal	1	no	4.894	14.715	EPSD	COSMIC	8.148	Gain
CMGC_CDK_CDK2_CDK2_ST	P55196	AFDN	P24941	CDK2	S1107	L1102I	1102	Missense	distal	-5	no	14.313	14.340	EPSD	COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	P55196	AFDN	P24941	CDK2	S1140	P1141H	1141	Missense	proximal	1	no	15.641	8.882	EPSD	COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	P55196	AFDN	P24941	CDK2	S1140	Q1137E	1137	Missense	distal	-3	no	15.641	15.757	EPSD	COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	P55196	AFDN	P24941	CDK2	S1143	P1141H	1141	Missense	proximal	-2	no	16.100	15.090	EPSD	COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	P55196	AFDN	P24941	CDK2	S1143	Q1137E	1137	Missense	distal	-6	no	16.100	16.099	EPSD	COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	P55196	AFDN	P24941	CDK2	S1173	H1170P	1170	Missense	distal	-3	no	11.334	11.188	EPSD	COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	P55196	AFDN	P24941	CDK2	S1173	N1178D	1178	Missense	distal	5	no	11.334	11.405	EPSD	COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	P55196	AFDN	P24941	CDK2	S1173	R1171H	1171	Missense	proximal	-2	no	11.334	11.560	EPSD	COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	P55196	AFDN	P24941	CDK2	S1182	N1178D	1178	Missense	distal	-4	no	14.503	14.891	EPSD	COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	P55196	AFDN	P24941	CDK2	T1211	T1211M	1211	Missense	central	0	yes	13.316	0.000	EPSD	COSMIC	8.148	Loss
CMGC_CDK_CDK2_CDK2_ST	P55196	AFDN	P24941	CDK2	T1211	P1214S	1214	Missense	distal	3	no	13.316	13.350	EPSD	COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	P55196	AFDN	P24941	CDK2	T1211	R1215K	1215	Missense	distal	4	no	13.316	13.838	EPSD	COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	P55196	AFDN	P24941	CDK2	T1211	P1213S	1213	Missense	proximal	2	no	13.316	13.383	EPSD	COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	P55196	AFDN	P24941	CDK2	S1275	R1274Q	1274	Missense	proximal	-1	no	9.192	8.314	EPSD	COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	P55196	AFDN	P24941	CDK2	S1275	R1271C	1271	Missense	distal	-4	no	9.192	8.683	EPSD	COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	P55196	AFDN	P24941	CDK2	S1275	S1275Y	1275	Missense	central	0	yes	9.192	0.000	EPSD	COSMIC	8.148	Loss
CMGC_CDK_CDK2_CDK2_ST	P55196	AFDN	P24941	CDK2	S1275	S1275F	1275	Missense	central	0	yes	9.192	0.000	EPSD	COSMIC	8.148	Loss
CMGC_CDK_CDK2_CDK2_ST	P55196	AFDN	P24941	CDK2	S1275	R1274H	1274	Missense	proximal	-1	no	9.192	8.741	EPSD	COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	P55196	AFDN	P24941	CDK2	S1275	R1280Q	1280	Missense	distal	5	no	9.192	9.046	EPSD	COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	P55196	AFDN	P24941	CDK2	S1275	R1274C	1274	Missense	proximal	-1	no	9.192	8.494	EPSD	COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	P55196	AFDN	P24941	CDK2	S1275	R1271H	1271	Missense	distal	-4	no	9.192	8.831	EPSD	COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	P55196	AFDN	P24941	CDK2	S1275	E1278K	1278	Missense	distal	3	no	9.192	11.278	EPSD	COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	P55196	AFDN	P24941	CDK2	S1275	E1277K	1277	Missense	proximal	2	no	9.192	8.954	EPSD	COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	P55196	AFDN	P24941	CDK2	S1311	L1312P	1312	Missense	proximal	1	no	2.474	12.295	EPSD	COSMIC	8.148	Gain
CMGC_CDK_CDK2_CDK2_ST	P55196	AFDN	P24941	CDK2	S1318	S1325F	1325	Missense	distal	7	no	7.371	8.224	EPSD	COSMIC	8.148	Gain
CMGC_CDK_CDK2_CDK2_ST	P55196	AFDN	P24941	CDK2	T1330	S1333F	1333	Missense	distal	3	no	12.191	12.116	EPSD	COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	P55196	AFDN	P24941	CDK2	T1330	S1326F	1326	Missense	distal	-4	no	12.191	11.229	EPSD	COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	P55196	AFDN	P24941	CDK2	T1330	H1324N	1324	Missense	distal	-6	no	12.191	12.187	EPSD	COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	P55196	AFDN	P24941	CDK2	T1330	P1331L	1331	Missense	proximal	1	no	12.191	2.370	EPSD	COSMIC	8.148	Loss
CMGC_CDK_CDK2_CDK2_ST	P55196	AFDN	P24941	CDK2	T1330	S1325F	1325	Missense	distal	-5	no	12.191	12.308	EPSD	COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	P55196	AFDN	P24941	CDK2	T1345	T1352I	1352	Missense	distal	7	no	10.320	10.680	EPSD	COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	P55196	AFDN	P24941	CDK2	T1345	T1345I	1345	Missense	central	0	yes	10.320	0.000	EPSD	COSMIC	8.148	Loss
CMGC_CDK_CDK2_CDK2_ST	P55196	AFDN	P24941	CDK2	T1345	P1350L	1350	Missense	distal	5	no	10.320	10.359	EPSD	COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	P55196	AFDN	P24941	CDK2	T1345	A1351S	1351	Missense	distal	6	no	10.320	10.325	EPSD	COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	P55196	AFDN	P24941	CDK2	T1352	V1356A	1356	Missense	distal	4	no	11.643	11.456	PhosphoSitePlus	COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	P55196	AFDN	P24941	CDK2	T1352	T1352I	1352	Missense	central	0	yes	11.643	0.000	PhosphoSitePlus	COSMIC	8.148	Loss
CMGC_CDK_CDK2_CDK2_ST	P55196	AFDN	P24941	CDK2	T1352	T1345I	1345	Missense	distal	-7	no	11.643	11.840	PhosphoSitePlus	COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	P55196	AFDN	P24941	CDK2	T1352	P1350L	1350	Missense	proximal	-2	no	11.643	11.419	PhosphoSitePlus	COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	P55196	AFDN	P24941	CDK2	T1352	A1351S	1351	Missense	proximal	-1	no	11.643	11.443	PhosphoSitePlus	COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	P55196	AFDN	P24941	CDK2	T1352	P1359L	1359	Missense	distal	7	no	11.643	11.674	PhosphoSitePlus	COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	P55196	AFDN	P24941	CDK2	S1357	I1360V	1360	Missense	distal	3	no	6.898	8.174	EPSD	COSMIC	8.148	Gain
CMGC_CDK_CDK2_CDK2_ST	P55196	AFDN	P24941	CDK2	S1455	A1459G	1459	Missense	distal	4	no	14.818	14.658	EPSD	COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	P55196	AFDN	P24941	CDK2	S1455	F1454L	1454	Missense	proximal	-1	no	14.818	13.852	EPSD	COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	P55196	AFDN	P24941	CDK2	S1455	A1452G	1452	Missense	distal	-3	no	14.818	14.980	EPSD	COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	P55196	AFDN	P24941	CDK2	S1455	P1456L	1456	Missense	proximal	1	no	14.818	4.997	EPSD	COSMIC	8.148	Loss
CMGC_CDK_CDK2_CDK2_ST	P55196	AFDN	P24941	CDK2	S1468	T1469P	1469	Missense	proximal	1	no	4.783	14.740	EPSD	COSMIC	8.148	Gain
CMGC_CDK_CDK2_CDK2_ST	P55196	AFDN	P24941	CDK2	S1512	L1511V	1511	Missense	proximal	-1	no	12.698	12.834	EPSD	COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	P55196	AFDN	P24941	CDK2	S1512	S1510N	1510	Missense	proximal	-2	no	12.698	12.006	EPSD	COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	P55196	AFDN	P24941	CDK2	S1512	P1515L	1515	Missense	distal	3	no	12.698	12.314	EPSD	COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	P55196	AFDN	P24941	CDK2	S1512	S1507L	1507	Missense	distal	-5	no	12.698	12.754	EPSD	COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	P55196	AFDN	P24941	CDK2	S1512	D1509Y	1509	Missense	distal	-3	no	12.698	12.748	EPSD	COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	P55196	AFDN	P24941	CDK2	S1512	S1506T	1506	Missense	distal	-6	no	12.698	12.699	EPSD	COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	P55196	AFDN	P24941	CDK2	S1512	D1514N	1514	Missense	proximal	2	no	12.698	12.630	EPSD	COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	P55196	AFDN	P24941	CDK2	S1512	S1506L	1506	Missense	distal	-6	no	12.698	12.699	EPSD	COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	P55196	AFDN	P24941	CDK2	S1696	R1690H	1690	Missense	distal	-6	no	14.356	14.358	EPSD	COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	P55196	AFDN	P24941	CDK2	S1696	S1698L	1698	Missense	proximal	2	no	14.356	14.183	EPSD	COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	P55196	AFDN	P24941	CDK2	S1696	P1699S	1699	Missense	distal	3	no	14.356	14.390	EPSD	COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	P55196	AFDN	P24941	CDK2	S1696	A1700G	1700	Missense	distal	4	no	14.356	14.196	EPSD	COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	P55196	AFDN	P24941	CDK2	S1696	R1690W	1690	Missense	distal	-6	no	14.356	14.362	EPSD	COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	P55196	AFDN	P24941	CDK2	S1696	D1691N	1691	Missense	distal	-5	no	14.356	14.318	EPSD	COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	P55196	AFDN	P24941	CDK2	S1698	S1698L	1698	Missense	central	0	yes	12.904	0.000	EPSD	COSMIC	8.148	Loss
CMGC_CDK_CDK2_CDK2_ST	P55196	AFDN	P24941	CDK2	S1698	P1699S	1699	Missense	proximal	1	no	12.904	1.638	EPSD	COSMIC	8.148	Loss
CMGC_CDK_CDK2_CDK2_ST	P55196	AFDN	P24941	CDK2	S1698	A1700G	1700	Missense	proximal	2	no	12.904	12.997	EPSD	COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	P55196	AFDN	P24941	CDK2	S1698	D1691N	1691	Missense	distal	-7	no	12.904	12.581	EPSD	COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	P55196	AFDN	P24941	CDK2	S1721	D1723N	1723	Missense	proximal	2	no	15.556	15.488	EPSD	COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	P55196	AFDN	P24941	CDK2	S1779	G1781E	1781	Missense	proximal	2	no	13.660	13.639	EPSD	COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	P55196	AFDN	P24941	CDK2	S1779	G1781V	1781	Missense	proximal	2	no	13.660	13.665	EPSD	COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	P55196	AFDN	P24941	CDK2	S1779	S1779L	1779	Missense	central	0	yes	13.660	0.000	EPSD	COSMIC	8.148	Loss
CMGC_CDK_CDK2_CDK2_ST	P55196	AFDN	P24941	CDK2	S1779	A1785P	1785	Missense	distal	6	no	13.660	13.664	EPSD	COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	P55196	AFDN	P24941	CDK2	S1779	P1780S	1780	Missense	proximal	1	no	13.660	2.394	EPSD	COSMIC	8.148	Loss
CMGC_CDK_CDK2_CDK2_ST	P55196	AFDN	P24941	CDK2	S1779	D1776N	1776	Missense	distal	-3	no	13.660	13.615	EPSD	COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	P55196	AFDN	P24941	CDK2	S1799	N1806D	1806	Missense	distal	7	no	7.905	8.685	EPSD	COSMIC	8.148	Gain
CMGC_CDK_CDK2_CDK2_ST	P55196	AFDN	P24941	CDK2	S1805	N1806D	1806	Missense	proximal	1	no	-24.059	8.309	EPSD	COSMIC	8.148	Gain
CMGC_CDK_CDK2_CDK2_ST	P10644	PRKAR1A	P24941	CDK2	T75	I82M	82	Missense	distal	7	no	7.966	8.454	EPSD	COSMIC	8.148	Gain
CMGC_CDK_CDK2_CDK2_ST	P10644	PRKAR1A	P24941	CDK2	S83	P86Q	86	Missense	distal	3	no	13.867	13.843	PhosphoSitePlus	COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	P10644	PRKAR1A	P24941	CDK2	S83	I82M	82	Missense	proximal	-1	no	13.867	14.934	PhosphoSitePlus	COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	P10644	PRKAR1A	P24941	CDK2	S83	E81K	81	Missense	proximal	-2	no	13.867	14.468	PhosphoSitePlus	COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	P10644	PRKAR1A	P24941	CDK2	S83	S83P	83	Missense	central	0	yes	13.867	0.000	PhosphoSitePlus	COSMIC	8.148	Loss
CMGC_CDK_CDK2_CDK2_ST	P10644	PRKAR1A	P24941	CDK2	S83	E81Q	81	Missense	proximal	-2	no	13.867	14.416	PhosphoSitePlus	COSMIC;GDSC;CCLE	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	P10644	PRKAR1A	P24941	CDK2	T209	P210L	210	Missense	proximal	1	no	13.976	4.156	EPSD	COSMIC	8.148	Loss
CMGC_CDK_CDK2_CDK2_ST	P10644	PRKAR1A	P24941	CDK2	T209	A213D	213	Missense	distal	4	no	13.976	13.872	EPSD	COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	P10644	PRKAR1A	P24941	CDK2	T209	Y207N	207	Missense	proximal	-2	no	13.976	13.198	EPSD	COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	P10644	PRKAR1A	P24941	CDK2	T209	I206T	206	Missense	distal	-3	no	13.976	13.917	EPSD	COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	Q15003	NCAPH	P24941	CDK2	T19	R20Q	20	Missense	proximal	1	no	8.021	9.907	EPSD	COSMIC;GDSC;CCLE	8.148	Gain
CMGC_CDK_CDK2_CDK2_ST	Q15003	NCAPH	P24941	CDK2	S28	P23L	23	Missense	distal	-5	no	15.447	15.459	EPSD	COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	Q15003	NCAPH	P24941	CDK2	S28	P29H	29	Missense	proximal	1	no	15.447	8.689	EPSD	COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	Q15003	NCAPH	P24941	CDK2	S28	G21R	21	Missense	distal	-7	no	15.447	15.467	EPSD	COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	Q15003	NCAPH	P24941	CDK2	S28	R32C	32	Missense	distal	4	no	15.447	14.820	EPSD	COSMIC;GDSC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	Q15003	NCAPH	P24941	CDK2	S28	R32H	32	Missense	distal	4	no	15.447	15.330	EPSD	COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	Q15003	NCAPH	P24941	CDK2	S81	S87P	87	Missense	distal	6	no	13.361	13.360	EPSD	COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	Q15003	NCAPH	P24941	CDK2	S81	R83C	83	Missense	proximal	2	no	13.361	13.348	EPSD	COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	Q15003	NCAPH	P24941	CDK2	S81	T79N	79	Missense	proximal	-2	no	13.361	12.052	EPSD	COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	Q15003	NCAPH	P24941	CDK2	S81	S87Y	87	Missense	distal	6	no	13.361	13.352	EPSD	COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	Q15003	NCAPH	P24941	CDK2	S87	S87P	87	Missense	central	0	yes	13.645	0.000	EPSD	COSMIC	8.148	Loss
CMGC_CDK_CDK2_CDK2_ST	Q15003	NCAPH	P24941	CDK2	S87	R83C	83	Missense	distal	-4	no	13.645	13.137	EPSD	COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	Q15003	NCAPH	P24941	CDK2	S87	D94H	94	Missense	distal	7	no	13.645	13.090	EPSD	COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	Q15003	NCAPH	P24941	CDK2	S87	S87Y	87	Missense	central	0	yes	13.645	0.000	EPSD	COSMIC	8.148	Loss
CMGC_CDK_CDK2_CDK2_ST	Q15003	NCAPH	P24941	CDK2	S138	E139D	139	Missense	proximal	1	no	7.369	8.291	EPSD	COSMIC	8.148	Gain
CMGC_CDK_CDK2_CDK2_ST	Q15003	NCAPH	P24941	CDK2	S359	D366N	366	Missense	distal	7	no	8.546	7.766	EPSD	COSMIC	8.148	Loss
CMGC_CDK_CDK2_CDK2_ST	Q15003	NCAPH	P24941	CDK2	S359	A354V	354	Missense	distal	-5	no	8.546	8.552	EPSD	COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	Q15003	NCAPH	P24941	CDK2	S359	P365L	365	Missense	distal	6	no	8.546	8.547	EPSD	COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	Q15003	NCAPH	P24941	CDK2	S359	I352T	352	Missense	distal	-7	no	8.546	8.349	EPSD	COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	Q15003	NCAPH	P24941	CDK2	S432	R434W	434	Missense	proximal	2	no	14.715	14.812	EPSD	COSMIC;GDSC;CCLE	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	Q15003	NCAPH	P24941	CDK2	S457	R451C	451	Missense	distal	-6	no	8.836	8.839	EPSD	COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	Q15003	NCAPH	P24941	CDK2	S457	N461K	461	Missense	distal	4	no	8.836	9.257	EPSD	COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	Q15003	NCAPH	P24941	CDK2	S457	P456S	456	Missense	proximal	-1	no	8.836	8.365	EPSD	COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	Q15003	NCAPH	P24941	CDK2	S459	N461K	461	Missense	proximal	2	no	9.482	9.412	EPSD	COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	Q15003	NCAPH	P24941	CDK2	S459	P456S	456	Missense	distal	-3	no	9.482	9.578	EPSD	COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	Q15003	NCAPH	P24941	CDK2	S570	E573K	573	Missense	distal	3	no	7.523	9.608	EPSD	COSMIC	8.148	Gain
CMGC_CDK_CDK2_CDK2_ST	Q15003	NCAPH	P24941	CDK2	S589	P592S	592	Missense	distal	3	no	15.135	15.169	EPSD	COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	Q15003	NCAPH	P24941	CDK2	S589	Y591H	591	Missense	proximal	2	no	15.135	15.155	EPSD	COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	Q15003	NCAPH	P24941	CDK2	S589	P595L	595	Missense	distal	6	no	15.135	15.137	EPSD	COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	Q15003	NCAPH	P24941	CDK2	S589	P596S	596	Missense	distal	7	no	15.135	14.983	EPSD	COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	Q15003	NCAPH	P24941	CDK2	S589	L588V	588	Missense	proximal	-1	no	15.135	15.271	EPSD	COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	Q15003	NCAPH	P24941	CDK2	S589	P595S	595	Missense	distal	6	no	15.135	15.137	EPSD	COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	Q15003	NCAPH	P24941	CDK2	T605	P606L	606	Missense	proximal	1	no	14.004	4.183	EPSD	COSMIC	8.148	Loss
CMGC_CDK_CDK2_CDK2_ST	Q15003	NCAPH	P24941	CDK2	T605	D612H	612	Missense	distal	7	no	14.004	13.449	EPSD	COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	Q15003	NCAPH	P24941	CDK2	S659	S659F	659	Missense	central	0	yes	9.039	0.000	EPSD	COSMIC	8.148	Loss
CMGC_CDK_CDK2_CDK2_ST	Q15003	NCAPH	P24941	CDK2	S659	A665V	665	Missense	distal	6	no	9.039	9.042	EPSD	COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	Q15003	NCAPH	P24941	CDK2	S733	L736R	736	Missense	distal	3	no	7.284	9.386	EPSD	COSMIC	8.148	Gain
CMGC_CDK_CDK2_CDK2_ST	Q92698	RAD54L	P24941	CDK2	T31	D24Y	24	Missense	distal	-7	no	16.646	16.531	EPSD;PhosphoSitePlus	COSMIC;GDSC;CCLE	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	Q92698	RAD54L	P24941	CDK2	T31	R33M	33	Missense	proximal	2	no	16.646	16.699	EPSD;PhosphoSitePlus	COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	Q92698	RAD54L	P24941	CDK2	T31	R35Q	35	Missense	distal	4	no	16.646	16.828	EPSD;PhosphoSitePlus	COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	Q92698	RAD54L	P24941	CDK2	S49	P50L	50	Missense	proximal	1	no	16.250	6.429	PhosphoSitePlus;EPSD	COSMIC	8.148	Loss
CMGC_CDK_CDK2_CDK2_ST	Q92698	RAD54L	P24941	CDK2	S49	P54S	54	Missense	distal	5	no	16.250	16.149	PhosphoSitePlus;EPSD	COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	Q92698	RAD54L	P24941	CDK2	S49	R52W	52	Missense	distal	3	no	16.250	13.610	PhosphoSitePlus;EPSD	COSMIC;GDSC;CCLE	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	Q92698	RAD54L	P24941	CDK2	S49	P50H	50	Missense	proximal	1	no	16.250	9.492	PhosphoSitePlus;EPSD	COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	Q92698	RAD54L	P24941	CDK2	S49	R52Q	52	Missense	distal	3	no	16.250	14.507	PhosphoSitePlus;EPSD	COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	Q92698	RAD54L	P24941	CDK2	S49	F47I	47	Missense	proximal	-2	no	16.250	17.209	PhosphoSitePlus;EPSD	COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	Q92698	RAD54L	P24941	CDK2	S49	P50A	50	Missense	proximal	1	no	16.250	1.847	PhosphoSitePlus;EPSD	COSMIC	8.148	Loss
CMGC_CDK_CDK2_CDK2_ST	P30304	CDC25A	P24941	CDK2	S18	P21A	21	Missense	distal	3	no	14.800	14.288	EPSD	COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	P30304	CDC25A	P24941	CDK2	S40	G37W	37	Missense	distal	-3	no	12.538	12.704	EPSD	COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	P30304	CDC25A	P24941	CDK2	S261	L264V	264	Missense	distal	3	no	12.875	13.867	EPSD	COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	P30304	CDC25A	P24941	CDK2	S298	S293N	293	Missense	distal	-5	no	13.338	13.401	EPSD	COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	P30304	CDC25A	P24941	CDK2	S321	P322L	322	Missense	proximal	1	no	13.607	3.786	EPSD	COSMIC	8.148	Loss
CMGC_CDK_CDK2_CDK2_ST	P30304	CDC25A	P24941	CDK2	S321	S320Y	320	Missense	proximal	-1	no	13.607	14.517	EPSD	COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	P30304	CDC25A	P24941	CDK2	S361	V368A	368	Missense	distal	7	no	12.936	13.062	EPSD	COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	P30304	CDC25A	P24941	CDK2	S361	S367F	367	Missense	distal	6	no	12.936	12.917	EPSD	COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	P30304	CDC25A	P24941	CDK2	S361	S367P	367	Missense	distal	6	no	12.936	12.935	EPSD	COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	P33981	TTK	P24941	CDK2	S49	N48S	48	Missense	proximal	-1	no	8.301	7.904	EPSD	COSMIC	8.148	Loss
CMGC_CDK_CDK2_CDK2_ST	P33981	TTK	P24941	CDK2	S49	T46A	46	Missense	distal	-3	no	8.301	8.282	EPSD	COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	P33981	TTK	P24941	CDK2	S80	P78L	78	Missense	proximal	-2	no	8.990	8.765	EPSD	COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	P33981	TTK	P24941	CDK2	S80	P78Q	78	Missense	proximal	-2	no	8.990	8.423	EPSD	COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	P33981	TTK	P24941	CDK2	S333	L339V	339	Missense	distal	6	no	12.107	12.104	EPSD	COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	P33981	TTK	P24941	CDK2	S333	E337K	337	Missense	distal	4	no	12.107	12.492	EPSD	COSMIC;GDSC;CCLE	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	P33981	TTK	P24941	CDK2	S333	K336R	336	Missense	distal	3	no	12.107	11.118	EPSD	COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	P33981	TTK	P24941	CDK2	S382	N383S	383	Missense	proximal	1	no	-20.441	8.905	EPSD	COSMIC	8.148	Gain
CMGC_CDK_CDK2_CDK2_ST	P33981	TTK	P24941	CDK2	S436	T441I	441	Missense	distal	5	no	12.873	12.991	EPSD;PhosphoSitePlus	COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	P33981	TTK	P24941	CDK2	T453	S455N	455	Missense	proximal	2	no	14.802	14.665	EPSD;PhosphoSitePlus	COSMIC;GDSC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	P33981	TTK	P24941	CDK2	T453	T458A	458	Missense	distal	5	no	14.802	14.838	EPSD;PhosphoSitePlus	COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	P33981	TTK	P24941	CDK2	T453	K452N	452	Missense	proximal	-1	no	14.802	14.829	EPSD;PhosphoSitePlus	COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	P33981	TTK	P24941	CDK2	T453	K452E	452	Missense	proximal	-1	no	14.802	15.687	EPSD;PhosphoSitePlus	COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	P33981	TTK	P24941	CDK2	T453	S455R	455	Missense	proximal	2	no	14.802	14.894	EPSD;PhosphoSitePlus	COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	P33981	TTK	P24941	CDK2	T453	S455I	455	Missense	proximal	2	no	14.802	14.713	EPSD;PhosphoSitePlus	COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	P33981	TTK	P24941	CDK2	T468	D474N	474	Missense	distal	6	no	16.886	16.905	PhosphoSitePlus;EPSD	COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	P33981	TTK	P24941	CDK2	T468	C465F	465	Missense	distal	-3	no	16.886	16.970	PhosphoSitePlus;EPSD	COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	P33981	TTK	P24941	CDK2	T468	T468A	468	Missense	central	0	yes	16.886	0.000	PhosphoSitePlus;EPSD	COSMIC	8.148	Loss
CMGC_CDK_CDK2_CDK2_ST	P33981	TTK	P24941	CDK2	T468	M463T	463	Missense	distal	-5	no	16.886	16.778	PhosphoSitePlus;EPSD	COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	P33981	TTK	P24941	CDK2	S821	P822S	822	Missense	proximal	1	no	13.752	2.486	EPSD	COSMIC	8.148	Loss
CMGC_CDK_CDK2_CDK2_ST	P33981	TTK	P24941	CDK2	S821	A828V	828	Missense	distal	7	no	13.752	13.626	EPSD	COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	P33981	TTK	P24941	CDK2	S821	N823H	823	Missense	proximal	2	no	13.752	13.900	EPSD	COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	P33981	TTK	P24941	CDK2	S837	N843I	843	Missense	distal	6	no	8.906	8.903	EPSD	COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	Q15813	TBCE	P24941	CDK2	T65	C61Y	61	Missense	distal	-4	no	7.356	8.573	EPSD	COSMIC;GDSC;CCLE	8.148	Gain
CMGC_CDK_CDK2_CDK2_ST	Q15813	TBCE	P24941	CDK2	S495	E494K	494	Missense	proximal	-1	no	16.954	16.069	PhosphoSitePlus	COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	Q15813	TBCE	P24941	CDK2	S495	E502K	502	Missense	distal	7	no	16.954	16.624	PhosphoSitePlus	COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	Q53GL7	PARP10	P24941	CDK2	T101	R104C	104	Missense	distal	3	no	14.904	8.540	PhosphoSitePlus	COSMIC;CCLE	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	Q53GL7	PARP10	P24941	CDK2	T101	G95A	95	Missense	distal	-6	no	14.904	14.900	PhosphoSitePlus	COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	Q53GL7	PARP10	P24941	CDK2	T101	P98H	98	Missense	distal	-3	no	14.904	15.050	PhosphoSitePlus	COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	Q53GL7	PARP10	P24941	CDK2	T101	Q107R	107	Missense	distal	6	no	14.904	14.882	PhosphoSitePlus	COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	Q53GL7	PARP10	P24941	CDK2	S128	R130Q	130	Missense	proximal	2	no	12.307	12.208	EPSD	COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	Q53GL7	PARP10	P24941	CDK2	S128	P129T	129	Missense	proximal	1	no	12.307	2.350	EPSD	COSMIC	8.148	Loss
CMGC_CDK_CDK2_CDK2_ST	Q53GL7	PARP10	P24941	CDK2	S128	D132Y	132	Missense	distal	4	no	12.307	12.572	EPSD	COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	Q53GL7	PARP10	P24941	CDK2	T310	G311R	311	Missense	proximal	1	no	9.528	7.042	EPSD	COSMIC	8.148	Loss
CMGC_CDK_CDK2_CDK2_ST	Q53GL7	PARP10	P24941	CDK2	T310	A306T	306	Missense	distal	-4	no	9.528	9.753	EPSD	COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	Q53GL7	PARP10	P24941	CDK2	T310	P312A	312	Missense	proximal	2	no	9.528	9.552	EPSD	COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	Q53GL7	PARP10	P24941	CDK2	S431	V430G	430	Missense	proximal	-1	no	10.502	11.594	EPSD	COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	Q53GL7	PARP10	P24941	CDK2	S431	A427S	427	Missense	distal	-4	no	10.502	10.915	EPSD	COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	Q53GL7	PARP10	P24941	CDK2	S431	A427V	427	Missense	distal	-4	no	10.502	10.513	EPSD	COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	Q53GL7	PARP10	P24941	CDK2	S1011	P1012S	1012	Missense	proximal	1	no	13.328	2.062	EPSD	COSMIC	8.148	Loss
CMGC_CDK_CDK2_CDK2_ST	Q53GL7	PARP10	P24941	CDK2	S1011	V1007L	1007	Missense	distal	-4	no	13.328	13.318	EPSD	COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	Q53ET0	CRTC2	P24941	CDK2	S86	P87L	87	Missense	proximal	1	no	14.848	5.028	EPSD	COSMIC	8.148	Loss
CMGC_CDK_CDK2_CDK2_ST	Q53ET0	CRTC2	P24941	CDK2	S90	P87L	87	Missense	distal	-3	no	10.698	10.627	EPSD	COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	Q53ET0	CRTC2	P24941	CDK2	S116	R120Q	120	Missense	distal	4	no	14.667	14.848	EPSD	COSMIC;GDSC;CCLE	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	Q53ET0	CRTC2	P24941	CDK2	S116	R120L	120	Missense	distal	4	no	14.667	14.899	EPSD	COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	Q53ET0	CRTC2	P24941	CDK2	S116	M114T	114	Missense	proximal	-2	no	14.667	16.718	EPSD	COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	Q53ET0	CRTC2	P24941	CDK2	S116	S116G	116	Missense	central	0	yes	14.667	0.000	EPSD	COSMIC	8.148	Loss
CMGC_CDK_CDK2_CDK2_ST	Q53ET0	CRTC2	P24941	CDK2	S116	T122P	122	Missense	distal	6	no	14.667	14.659	EPSD	COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	Q53ET0	CRTC2	P24941	CDK2	S116	R109H	109	Missense	distal	-7	no	14.667	14.446	EPSD	COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	Q53ET0	CRTC2	P24941	CDK2	S128	P132H	132	Missense	distal	4	no	15.585	15.347	EPSD	COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	Q53ET0	CRTC2	P24941	CDK2	S131	P132H	132	Missense	proximal	1	no	13.335	6.576	EPSD	COSMIC	8.148	Loss
CMGC_CDK_CDK2_CDK2_ST	Q53ET0	CRTC2	P24941	CDK2	S131	S136L	136	Missense	distal	5	no	13.335	13.475	EPSD	COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	Q53ET0	CRTC2	P24941	CDK2	S131	P138L	138	Missense	distal	7	no	13.335	13.365	EPSD	COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	Q53ET0	CRTC2	P24941	CDK2	S136	P132H	132	Missense	distal	-4	no	14.361	13.757	EPSD	COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	Q53ET0	CRTC2	P24941	CDK2	S136	S136L	136	Missense	central	0	yes	14.361	0.000	EPSD	COSMIC	8.148	Loss
CMGC_CDK_CDK2_CDK2_ST	Q53ET0	CRTC2	P24941	CDK2	S136	P138L	138	Missense	proximal	2	no	14.361	14.254	EPSD	COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	Q53ET0	CRTC2	P24941	CDK2	S183	M180K	180	Missense	distal	-3	no	12.820	12.411	EPSD	COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	Q53ET0	CRTC2	P24941	CDK2	S336	G333E	333	Missense	distal	-3	no	12.451	12.522	EPSD	COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	Q53ET0	CRTC2	P24941	CDK2	S336	G333W	333	Missense	distal	-3	no	12.451	12.617	EPSD	COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	Q53ET0	CRTC2	P24941	CDK2	S336	L343M	343	Missense	distal	7	no	12.451	12.966	EPSD	COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	Q53ET0	CRTC2	P24941	CDK2	S358	A354S	354	Missense	distal	-4	no	15.872	16.285	EPSD	COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	Q53ET0	CRTC2	P24941	CDK2	S358	P361R	361	Missense	distal	3	no	15.872	17.590	EPSD	COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	Q53ET0	CRTC2	P24941	CDK2	S368	P361R	361	Missense	distal	-7	no	7.913	8.257	EPSD	COSMIC	8.148	Gain
CMGC_CDK_CDK2_CDK2_ST	Q53ET0	CRTC2	P24941	CDK2	S408	A413V	413	Missense	distal	5	no	12.976	12.933	EPSD	COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	Q53ET0	CRTC2	P24941	CDK2	S408	P409L	409	Missense	proximal	1	no	12.976	3.155	EPSD	COSMIC	8.148	Loss
CMGC_CDK_CDK2_CDK2_ST	Q53ET0	CRTC2	P24941	CDK2	T420	A413V	413	Missense	distal	-7	no	13.202	13.057	EPSD	COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	Q53ET0	CRTC2	P24941	CDK2	S424	R428H	428	Missense	distal	4	no	14.789	14.672	EPSD	COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	Q53ET0	CRTC2	P24941	CDK2	S424	V430A	430	Missense	distal	6	no	14.789	14.786	EPSD	COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	Q53ET0	CRTC2	P24941	CDK2	S433	V430A	430	Missense	distal	-3	no	13.266	13.064	PhosphoSitePlus	COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	Q53ET0	CRTC2	P24941	CDK2	S490	P484S	484	Missense	distal	-6	no	12.845	12.844	EPSD	COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	Q53ET0	CRTC2	P24941	CDK2	S490	P491T	491	Missense	proximal	1	no	12.845	2.887	EPSD	COSMIC	8.148	Loss
CMGC_CDK_CDK2_CDK2_ST	Q53ET0	CRTC2	P24941	CDK2	S490	Y488F	488	Missense	proximal	-2	no	12.845	12.296	EPSD	COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	Q53ET0	CRTC2	P24941	CDK2	T501	P508R	508	Missense	distal	7	no	14.544	15.034	EPSD	COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	Q53ET0	CRTC2	P24941	CDK2	T501	Q498E	498	Missense	distal	-3	no	14.544	14.660	EPSD	COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	Q53ET0	CRTC2	P24941	CDK2	S624	S623F	623	Missense	proximal	-1	no	13.549	14.806	EPSD	COSMIC;GDSC;CCLE	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	O15350	TP73	P24941	CDK2	S8	T13M	13	Missense	distal	5	no	13.666	13.999	EPSD	COSMIC;GDSC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	O15350	TP73	P24941	CDK2	T86	A90T	90	Missense	distal	4	no	17.190	17.432	PhosphoSitePlus	COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	O15350	TP73	P24941	CDK2	T86	H89P	89	Missense	distal	3	no	17.190	16.167	PhosphoSitePlus	COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	O15350	TP73	P24941	CDK2	T167	Q162R	162	Missense	distal	-5	no	13.388	13.434	EPSD	COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	O15350	TP73	P24941	CDK2	T167	A174G	174	Missense	distal	7	no	13.388	13.673	EPSD	COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	O15350	TP73	P24941	CDK2	T167	S166F	166	Missense	proximal	-1	no	13.388	14.645	EPSD	COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	O15350	TP73	P24941	CDK2	T167	P171L	171	Missense	distal	4	no	13.388	13.500	EPSD	COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	O15350	TP73	P24941	CDK2	T173	A174G	174	Missense	proximal	1	no	3.135	10.226	EPSD	COSMIC	8.148	Gain
CMGC_CDK_CDK2_CDK2_ST	O15350	TP73	P24941	CDK2	S333	S333R	333	Missense	central	0	yes	11.658	0.000	EPSD	COSMIC	8.148	Loss
CMGC_CDK_CDK2_CDK2_ST	O15350	TP73	P24941	CDK2	S333	P335L	335	Missense	proximal	2	no	11.658	11.551	EPSD	COSMIC;GDSC;CCLE	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	O15350	TP73	P24941	CDK2	S412	M414I	414	Missense	proximal	2	no	12.065	11.831	EPSD	COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	O15350	TP73	P24941	CDK2	S412	S412L	412	Missense	central	0	yes	12.065	0.000	EPSD	COSMIC	8.148	Loss
CMGC_CDK_CDK2_CDK2_ST	O15350	TP73	P24941	CDK2	S412	S406P	406	Missense	distal	-6	no	12.065	12.066	EPSD	COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	P31943	HNRNPH1	P24941	CDK2	S104	D106G	106	Missense	proximal	2	no	14.665	14.786	PhosphoSitePlus	COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	P31943	HNRNPH1	P24941	CDK2	S269	Y276D	276	Missense	distal	7	no	9.029	9.446	EPSD	COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	P31943	HNRNPH1	P24941	CDK2	S272	Y276D	276	Missense	distal	4	no	8.746	8.482	EPSD	COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	P31943	HNRNPH1	P24941	CDK2	S346	K347Q	347	Missense	proximal	1	no	1.354	11.092	EPSD	COSMIC	8.148	Gain
CMGC_CDK_CDK2_CDK2_ST	Q99708	RBBP8	P24941	CDK2	S10	S7R	7	Missense	distal	-3	no	13.152	13.246	EPSD	COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	Q99708	RBBP8	P24941	CDK2	S10	S4L	4	Missense	distal	-6	no	13.152	13.153	EPSD	COSMIC;GDSC;CCLE	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	Q99708	RBBP8	P24941	CDK2	S276	S276N	276	Missense	central	0	yes	13.112	0.000	EPSD	COSMIC	8.148	Loss
CMGC_CDK_CDK2_CDK2_ST	Q99708	RBBP8	P24941	CDK2	T315	P322H	322	Missense	distal	7	no	15.012	15.143	PhosphoSitePlus;EPSD	COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	Q99708	RBBP8	P24941	CDK2	T315	E320K	320	Missense	distal	5	no	15.012	14.879	PhosphoSitePlus;EPSD	COSMIC;GDSC;CCLE	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	Q99708	RBBP8	P24941	CDK2	S327	P322H	322	Missense	distal	-5	no	13.862	13.909	EPSD	COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	Q99708	RBBP8	P24941	CDK2	S327	G331V	331	Missense	distal	4	no	13.862	14.208	EPSD	COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	Q99708	RBBP8	P24941	CDK2	S327	E320K	320	Missense	distal	-7	no	13.862	13.724	EPSD	COSMIC;GDSC;CCLE	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	Q99708	RBBP8	P24941	CDK2	S347	G354V	354	Missense	distal	7	no	14.542	14.130	EPSD	COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	Q99708	RBBP8	P24941	CDK2	T450	E453K	453	Missense	distal	3	no	6.518	8.603	EPSD	COSMIC	8.148	Gain
CMGC_CDK_CDK2_CDK2_ST	Q99708	RBBP8	P24941	CDK2	S454	E457K	457	Missense	distal	3	no	8.116	10.202	EPSD	COSMIC;GDSC;CCLE	8.148	Gain
CMGC_CDK_CDK2_CDK2_ST	Q99708	RBBP8	P24941	CDK2	S549	P546S	546	Missense	distal	-3	no	14.273	14.368	EPSD	COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	Q99708	RBBP8	P24941	CDK2	S549	E552Q	552	Missense	distal	3	no	14.273	13.626	EPSD	COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	Q99708	RBBP8	P24941	CDK2	S549	E552D	552	Missense	distal	3	no	14.273	11.837	EPSD	COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	Q99708	RBBP8	P24941	CDK2	S568	L564F	564	Missense	distal	-4	no	14.873	14.324	EPSD	COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	Q99708	RBBP8	P24941	CDK2	T847	P844S	844	Missense	distal	-3	no	15.525	15.621	EPSD;PhosphoSitePlus	COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	Q99708	RBBP8	P24941	CDK2	S889	Q882E	882	Missense	distal	-7	no	17.646	17.779	EPSD	COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	Q9NYB0	TERF2IP	P24941	CDK2	S36	P35L	35	Missense	proximal	-1	no	16.320	16.140	EPSD	COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	Q9NYB0	TERF2IP	P24941	CDK2	S111	S111L	111	Missense	central	0	yes	9.365	0.000	EPSD	COSMIC	8.148	Loss
CMGC_CDK_CDK2_CDK2_ST	Q9NYB0	TERF2IP	P24941	CDK2	S111	A104V	104	Missense	distal	-7	no	9.365	9.220	EPSD	COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	Q9NYB0	TERF2IP	P24941	CDK2	S269	P271L	271	Missense	proximal	2	no	14.028	13.921	EPSD	COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	P04183	TK1	P24941	CDK2	S13	S13F	13	Missense	central	0	yes	15.982	0.000	PhosphoSitePlus	COSMIC;CCLE	8.148	Loss
CMGC_CDK_CDK2_CDK2_ST	P04183	TK1	P24941	CDK2	S231	S231R	231	Missense	central	0	yes	13.098	0.000	EPSD	COSMIC	8.148	Loss
CMGC_CDK_CDK2_CDK2_ST	P04183	TK1	P24941	CDK2	S231	C230Y	230	Missense	proximal	-1	no	13.098	13.664	EPSD	COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	P04183	TK1	P24941	CDK2	S231	Q225R	225	Missense	distal	-6	no	13.098	13.097	EPSD	COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	A1KXE4	FAM168B	P24941	CDK2	S6	S6I	6	Missense	central	0	yes	13.135	0.000	EPSD	COSMIC	8.148	Loss
CMGC_CDK_CDK2_CDK2_ST	A1KXE4	FAM168B	P24941	CDK2	S166	L161M	161	Missense	distal	-5	no	13.474	13.569	EPSD	COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	A1KXE4	FAM168B	P24941	CDK2	T168	L161M	161	Missense	distal	-7	no	13.230	13.725	EPSD	COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	A1KXE4	FAM168B	P24941	CDK2	T168	P174L	174	Missense	distal	6	no	13.230	13.231	EPSD	COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	A1KXE4	FAM168B	P24941	CDK2	T185	G184E	184	Missense	proximal	-1	no	14.540	14.276	EPSD	COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	Q13330	MTA1	P24941	CDK2	S386	G390D	390	Missense	distal	4	no	12.106	12.161	EPSD	COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	Q13330	MTA1	P24941	CDK2	S386	C393Y	393	Missense	distal	7	no	12.106	11.734	EPSD	COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	Q13330	MTA1	P24941	CDK2	T399	S406F	406	Missense	distal	7	no	8.240	9.094	EPSD	COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	Q13330	MTA1	P24941	CDK2	T399	C393Y	393	Missense	distal	-6	no	8.240	8.235	EPSD	COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	Q13330	MTA1	P24941	CDK2	S449	L453I	453	Missense	distal	4	no	13.678	13.537	EPSD	COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	Q13330	MTA1	P24941	CDK2	S460	L453I	453	Missense	distal	-7	no	14.856	15.045	EPSD	COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	Q13330	MTA1	P24941	CDK2	T564	A569V	569	Missense	distal	5	no	17.708	17.665	EPSD	COSMIC;GDSC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	Q13330	MTA1	P24941	CDK2	T564	A566S	566	Missense	proximal	2	no	17.708	17.750	EPSD	COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	Q13330	MTA1	P24941	CDK2	S576	A569V	569	Missense	distal	-7	no	13.103	12.958	EPSD	COSMIC;GDSC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	Q96E09	FAM122A	P24941	CDK2	S173	S166G	166	Missense	distal	-7	no	13.644	14.148	EPSD	COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	Q6P1N0	CC2D1A	P24941	CDK2	T120	E113G	113	Missense	distal	-7	no	15.093	15.327	EPSD	COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	Q6P1N0	CC2D1A	P24941	CDK2	T120	P123S	123	Missense	distal	3	no	15.093	15.127	EPSD	COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	Q6P1N0	CC2D1A	P24941	CDK2	T120	A117T	117	Missense	distal	-3	no	15.093	15.112	EPSD	COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	Q6P1N0	CC2D1A	P24941	CDK2	T120	A125T	125	Missense	distal	5	no	15.093	15.057	EPSD	COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	Q6P1N0	CC2D1A	P24941	CDK2	S239	A235G	235	Missense	distal	-4	no	12.662	12.403	EPSD	COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	Q6P1N0	CC2D1A	P24941	CDK2	S253	L257V	257	Missense	distal	4	no	14.311	14.426	EPSD	COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	Q6P1N0	CC2D1A	P24941	CDK2	S324	S327L	327	Missense	distal	3	no	13.414	12.997	EPSD	COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	Q6P1N0	CC2D1A	P24941	CDK2	S324	L318P	318	Missense	distal	-6	no	13.414	13.415	EPSD	COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	Q6P1N0	CC2D1A	P24941	CDK2	T331	S327L	327	Missense	distal	-4	no	13.394	12.982	EPSD	COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	Q6P1N0	CC2D1A	P24941	CDK2	T470	S468P	468	Missense	proximal	-2	no	12.942	13.593	EPSD	COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	Q6P1N0	CC2D1A	P24941	CDK2	T470	P466T	466	Missense	distal	-4	no	12.942	13.108	EPSD	COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	Q6P1N0	CC2D1A	P24941	CDK2	T470	P471S	471	Missense	proximal	1	no	12.942	1.676	EPSD	COSMIC	8.148	Loss
CMGC_CDK_CDK2_CDK2_ST	Q6P1N0	CC2D1A	P24941	CDK2	T669	I665F	665	Missense	distal	-4	no	13.449	12.992	EPSD	COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	Q6P1N0	CC2D1A	P24941	CDK2	T669	V662M	662	Missense	distal	-7	no	13.449	13.931	EPSD	COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	Q6P1N0	CC2D1A	P24941	CDK2	S837	R843Q	843	Missense	distal	6	no	9.405	9.427	EPSD	COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	Q6P1N0	CC2D1A	P24941	CDK2	S837	E836D	836	Missense	proximal	-1	no	9.405	9.376	EPSD	COSMIC;GDSC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	Q6P1N0	CC2D1A	P24941	CDK2	S837	R843L	843	Missense	distal	6	no	9.405	9.423	EPSD	COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	Q53H80	AKIRIN2	P24941	CDK2	S134	P135A	135	Missense	proximal	1	no	18.141	3.738	EPSD	COSMIC	8.148	Loss
CMGC_CDK_CDK2_CDK2_ST	P54198	HIRA	P24941	CDK2	T508	S511F	511	Missense	distal	3	no	11.841	11.766	EPSD	COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	P54198	HIRA	P24941	CDK2	S549	P556S	556	Missense	distal	7	no	16.587	16.435	EPSD	COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	P54198	HIRA	P24941	CDK2	S549	P556L	556	Missense	distal	7	no	16.587	16.618	EPSD	COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	P54198	HIRA	P24941	CDK2	T555	P556S	556	Missense	proximal	1	no	17.342	6.077	PhosphoSitePlus	COSMIC	8.148	Loss
CMGC_CDK_CDK2_CDK2_ST	P54198	HIRA	P24941	CDK2	T555	P556L	556	Missense	proximal	1	no	17.342	7.522	PhosphoSitePlus	COSMIC	8.148	Loss
CMGC_CDK_CDK2_CDK2_ST	P54198	HIRA	P24941	CDK2	T576	R572P	572	Missense	distal	-4	no	12.717	12.960	EPSD	COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	P54198	HIRA	P24941	CDK2	T576	R572Q	572	Missense	distal	-4	no	12.717	12.742	EPSD	COSMIC;GDSC;CCLE	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	P54198	HIRA	P24941	CDK2	T586	M585K	585	Missense	proximal	-1	no	15.477	14.327	EPSD	COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	P54198	HIRA	P24941	CDK2	T586	R592S	592	Missense	distal	6	no	15.477	15.495	EPSD	COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	P54198	HIRA	P24941	CDK2	S614	D615N	615	Missense	proximal	1	no	8.248	-24.120	EPSD	COSMIC	8.148	Loss
CMGC_CDK_CDK2_CDK2_ST	P54198	HIRA	P24941	CDK2	S661	A667T	667	Missense	distal	6	no	12.205	12.217	EPSD	COSMIC;GDSC;CCLE	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	P54198	HIRA	P24941	CDK2	S661	P654S	654	Missense	distal	-7	no	12.205	12.025	EPSD	COSMIC;GDSC;CCLE	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	P54198	HIRA	P24941	CDK2	S687	R690T	690	Missense	distal	3	no	18.403	16.570	EPSD	COSMIC;GDSC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	P54198	HIRA	P24941	CDK2	S769	R766L	766	Missense	distal	-3	no	11.894	11.634	EPSD	COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	P54198	HIRA	P24941	CDK2	S769	P770L	770	Missense	proximal	1	no	11.894	2.073	EPSD	COSMIC	8.148	Loss
CMGC_CDK_CDK2_CDK2_ST	P54198	HIRA	P24941	CDK2	S775	P770L	770	Missense	distal	-5	no	14.723	14.734	EPSD	COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	Q01167	FOXK2	P24941	CDK2	S170	E166K	166	Missense	distal	-4	no	16.266	15.955	EPSD	COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	Q01167	FOXK2	P24941	CDK2	S170	Q176L	176	Missense	distal	6	no	16.266	16.262	EPSD	COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	Q01167	FOXK2	P24941	CDK2	S180	H178Y	178	Missense	proximal	-2	no	10.223	10.669	EPSD	COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	Q01167	FOXK2	P24941	CDK2	S180	Q176L	176	Missense	distal	-4	no	10.223	10.383	EPSD	COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	Q01167	FOXK2	P24941	CDK2	S180	I179V	179	Missense	proximal	-1	no	10.223	10.197	EPSD	COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	Q01167	FOXK2	P24941	CDK2	S195	S199F	199	Missense	distal	4	no	14.585	14.389	EPSD	COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	Q01167	FOXK2	P24941	CDK2	S195	A191T	191	Missense	distal	-4	no	14.585	14.810	EPSD	COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	Q01167	FOXK2	P24941	CDK2	S195	P198S	198	Missense	distal	3	no	14.585	14.619	EPSD	COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	Q01167	FOXK2	P24941	CDK2	S199	S199F	199	Missense	central	0	yes	13.080	0.000	EPSD	COSMIC	8.148	Loss
CMGC_CDK_CDK2_CDK2_ST	Q01167	FOXK2	P24941	CDK2	S199	P198S	198	Missense	proximal	-1	no	13.080	12.609	EPSD	COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	Q01167	FOXK2	P24941	CDK2	S213	S220A	220	Missense	distal	7	no	14.683	15.220	EPSD	COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	Q01167	FOXK2	P24941	CDK2	S213	G216K	216	Missense	distal	3	no	14.683	17.492	EPSD	COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	Q01167	FOXK2	P24941	CDK2	S220	S220A	220	Missense	central	0	yes	8.192	0.000	EPSD	COSMIC	8.148	Loss
CMGC_CDK_CDK2_CDK2_ST	Q01167	FOXK2	P24941	CDK2	S220	G216K	216	Missense	distal	-4	no	8.192	8.429	EPSD	COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	Q01167	FOXK2	P24941	CDK2	S252	S248L	248	Missense	distal	-4	no	14.392	13.979	EPSD	COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	Q01167	FOXK2	P24941	CDK2	T360	R353M	353	Missense	distal	-7	no	9.430	9.587	EPSD	COSMIC;CCLE	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	Q01167	FOXK2	P24941	CDK2	S373	P374S	374	Missense	proximal	1	no	14.662	3.396	PhosphoSitePlus;EPSD	COSMIC	8.148	Loss
CMGC_CDK_CDK2_CDK2_ST	Q01167	FOXK2	P24941	CDK2	T552	Q547H	547	Missense	distal	-5	no	12.870	12.917	EPSD	COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	Q01167	FOXK2	P24941	CDK2	T552	T551S	551	Missense	proximal	-1	no	12.870	12.662	EPSD	COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	Q01167	FOXK2	P24941	CDK2	T552	V557L	557	Missense	distal	5	no	12.870	12.943	EPSD	COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	Q01167	FOXK2	P24941	CDK2	S599	P600S	600	Missense	proximal	1	no	15.293	4.027	EPSD	COSMIC	8.148	Loss
CMGC_CDK_CDK2_CDK2_ST	Q01167	FOXK2	P24941	CDK2	S599	A597T	597	Missense	proximal	-2	no	15.293	15.244	EPSD	COSMIC;CCLE	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	Q01167	FOXK2	P24941	CDK2	T648	T648M	648	Missense	central	0	yes	15.161	0.000	EPSD	COSMIC	8.148	Loss
CMGC_CDK_CDK2_CDK2_ST	Q01167	FOXK2	P24941	CDK2	T648	V653I	653	Missense	distal	5	no	15.161	15.287	EPSD	COSMIC;CCLE	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	P30307	CDC25C	P24941	CDK2	T48	L54V	54	Missense	distal	6	no	13.569	13.566	EPSD	COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	P30307	CDC25C	P24941	CDK2	T48	V50A	50	Missense	proximal	2	no	13.569	13.471	EPSD	COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	P30307	CDC25C	P24941	CDK2	T48	P49Q	49	Missense	proximal	1	no	13.569	5.657	EPSD	COSMIC	8.148	Loss
CMGC_CDK_CDK2_CDK2_ST	P30307	CDC25C	P24941	CDK2	T48	F53L	53	Missense	distal	5	no	13.569	13.391	EPSD	COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	P30307	CDC25C	P24941	CDK2	T67	R70L	70	Missense	distal	3	no	15.210	13.108	EPSD	COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	P30307	CDC25C	P24941	CDK2	S122	S122N	122	Missense	central	0	yes	14.438	0.000	EPSD	COSMIC	8.148	Loss
CMGC_CDK_CDK2_CDK2_ST	P30307	CDC25C	P24941	CDK2	T130	P131S	131	Missense	proximal	1	no	10.654	-0.612	EPSD	COSMIC	8.148	Loss
CMGC_CDK_CDK2_CDK2_ST	P30307	CDC25C	P24941	CDK2	T130	P131L	131	Missense	proximal	1	no	10.654	0.833	EPSD	COSMIC;GDSC;CCLE	8.148	Loss
CMGC_CDK_CDK2_CDK2_ST	P30307	CDC25C	P24941	CDK2	T130	G137R	137	Missense	distal	7	no	10.654	10.473	EPSD	COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	P30307	CDC25C	P24941	CDK2	S168	S168F	168	Missense	central	0	yes	16.715	0.000	EPSD	COSMIC	8.148	Loss
CMGC_CDK_CDK2_CDK2_ST	P30307	CDC25C	P24941	CDK2	S168	S161L	161	Missense	distal	-7	no	16.715	16.900	EPSD	COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	P30307	CDC25C	P24941	CDK2	S214	S216L	216	Missense	proximal	2	no	13.103	12.930	PhosphoSitePlus	COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	P30307	CDC25C	P24941	CDK2	S214	G210R	210	Missense	distal	-4	no	13.103	13.178	PhosphoSitePlus	COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	Q9Y2K7	KDM2A	P24941	CDK2	S394	S387F	387	Missense	distal	-7	no	14.691	15.242	EPSD	COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	Q9Y2K7	KDM2A	P24941	CDK2	T550	R548W	548	Missense	proximal	-2	no	14.987	14.488	PhosphoSitePlus	COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	Q9Y2K7	KDM2A	P24941	CDK2	T550	A555V	555	Missense	distal	5	no	14.987	14.944	PhosphoSitePlus	COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	Q9Y2K7	KDM2A	P24941	CDK2	S558	A555V	555	Missense	distal	-3	no	15.036	15.237	EPSD	COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	Q9Y2K7	KDM2A	P24941	CDK2	S562	A555V	555	Missense	distal	-7	no	8.245	8.100	EPSD	COSMIC	8.148	Loss
CMGC_CDK_CDK2_CDK2_ST	Q9Y2K7	KDM2A	P24941	CDK2	T713	E710D	710	Missense	distal	-3	no	15.120	15.010	EPSD	COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	Q9Y2K7	KDM2A	P24941	CDK2	S718	M722I	722	Missense	distal	4	no	10.154	10.546	EPSD	COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	Q9Y2K7	KDM2A	P24941	CDK2	S718	S721F	721	Missense	distal	3	no	10.154	10.078	EPSD	COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	Q9Y2K7	KDM2A	P24941	CDK2	S731	V736L	736	Missense	distal	5	no	12.131	12.204	EPSD	COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	Q9Y2K7	KDM2A	P24941	CDK2	S731	S731P	731	Missense	central	0	yes	12.131	0.000	EPSD	COSMIC	8.148	Loss
CMGC_CDK_CDK2_CDK2_ST	Q9Y2K7	KDM2A	P24941	CDK2	S731	R738W	738	Missense	distal	7	no	12.131	12.531	EPSD	COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	Q9Y2K7	KDM2A	P24941	CDK2	S731	S731F	731	Missense	central	0	yes	12.131	0.000	EPSD	COSMIC;GDSC;CCLE	8.148	Loss
CMGC_CDK_CDK2_CDK2_ST	Q9Y2K7	KDM2A	P24941	CDK2	S740	V736L	736	Missense	distal	-4	no	13.188	13.177	EPSD	COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	Q9Y2K7	KDM2A	P24941	CDK2	S740	S740F	740	Missense	central	0	yes	13.188	0.000	EPSD	COSMIC	8.148	Loss
CMGC_CDK_CDK2_CDK2_ST	Q9Y2K7	KDM2A	P24941	CDK2	S740	D747N	747	Missense	distal	7	no	13.188	12.408	EPSD	COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	Q9Y2K7	KDM2A	P24941	CDK2	S740	R738W	738	Missense	proximal	-2	no	13.188	12.688	EPSD	COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	Q9Y2K7	KDM2A	P24941	CDK2	S781	K776N	776	Missense	distal	-5	no	8.153	8.169	EPSD	COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	Q9Y2K7	KDM2A	P24941	CDK2	S781	E785D	785	Missense	distal	4	no	8.153	8.071	EPSD	COSMIC	8.148	Loss
CMGC_CDK_CDK2_CDK2_ST	Q9Y2K7	KDM2A	P24941	CDK2	S781	N778K	778	Missense	distal	-3	no	8.153	8.092	EPSD	COSMIC	8.148	Loss
CMGC_CDK_CDK2_CDK2_ST	Q9Y2K7	KDM2A	P24941	CDK2	S832	R834L	834	Missense	proximal	2	no	14.498	14.233	EPSD	COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	Q9Y2K7	KDM2A	P24941	CDK2	S832	S826F	826	Missense	distal	-6	no	14.498	14.503	EPSD	COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	Q9Y2K7	KDM2A	P24941	CDK2	S832	L829F	829	Missense	distal	-3	no	14.498	14.756	EPSD	COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	Q9Y2K7	KDM2A	P24941	CDK2	S832	R834H	834	Missense	proximal	2	no	14.498	14.417	EPSD	COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	Q9Y2K7	KDM2A	P24941	CDK2	S832	R834S	834	Missense	proximal	2	no	14.498	14.406	EPSD	COSMIC;GDSC;CCLE	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	Q9Y2K7	KDM2A	P24941	CDK2	S832	R830C	830	Missense	proximal	-2	no	14.498	14.672	EPSD	COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	Q9Y2K7	KDM2A	P24941	CDK2	S832	S832F	832	Missense	central	0	yes	14.498	0.000	EPSD	COSMIC	8.148	Loss
CMGC_CDK_CDK2_CDK2_ST	Q9Y2K7	KDM2A	P24941	CDK2	T844	R843Q	843	Missense	proximal	-1	no	14.667	13.789	EPSD	COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	Q9Y2K7	KDM2A	P24941	CDK2	T1024	R1020Q	1020	Missense	distal	-4	no	14.432	14.457	EPSD	COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	Q9Y2K7	KDM2A	P24941	CDK2	T1024	P1025L	1025	Missense	proximal	1	no	14.432	4.611	EPSD	COSMIC	8.148	Loss
CMGC_CDK_CDK2_CDK2_ST	Q14207	NPAT	P24941	CDK2	S207	G209S	209	Missense	proximal	2	no	16.393	16.342	EPSD	COSMIC;GDSC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	Q14207	NPAT	P24941	CDK2	S535	K529N	529	Missense	distal	-6	no	8.532	8.531	EPSD	COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	Q14207	NPAT	P24941	CDK2	S535	D537N	537	Missense	proximal	2	no	8.532	8.464	EPSD	COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	Q14207	NPAT	P24941	CDK2	S752	E755K	755	Missense	distal	3	no	6.811	8.896	EPSD	COSMIC	8.148	Gain
CMGC_CDK_CDK2_CDK2_ST	Q14207	NPAT	P24941	CDK2	S779	A784T	784	Missense	distal	5	no	17.533	17.497	EPSD;PhosphoSitePlus	COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	Q14207	NPAT	P24941	CDK2	S1100	D1099G	1099	Missense	proximal	-1	no	14.290	14.583	PhosphoSitePlus;EPSD	COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	Q14207	NPAT	P24941	CDK2	S1100	P1101L	1101	Missense	proximal	1	no	14.290	4.469	PhosphoSitePlus;EPSD	COSMIC	8.148	Loss
CMGC_CDK_CDK2_CDK2_ST	Q14207	NPAT	P24941	CDK2	T1350	D1354H	1354	Missense	distal	4	no	14.828	14.656	EPSD;PhosphoSitePlus	COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	Q01196	RUNX1	P24941	CDK2	T14	T14M	14	Missense	central	0	yes	12.669	0.000	EPSD	COSMIC	8.148	Loss
CMGC_CDK_CDK2_CDK2_ST	Q01196	RUNX1	P24941	CDK2	S21	K24N	24	Missense	distal	3	no	16.779	13.509	EPSD	COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	Q01196	RUNX1	P24941	CDK2	S21	M25K	25	Missense	distal	4	no	16.779	17.601	EPSD	COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	Q01196	RUNX1	P24941	CDK2	S21	E27Q	27	Missense	distal	6	no	16.779	16.787	EPSD	COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	Q01196	RUNX1	P24941	CDK2	S21	A28E	28	Missense	distal	7	no	16.779	16.438	EPSD	COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	Q01196	RUNX1	P24941	CDK2	S21	P22L	22	Missense	proximal	1	no	16.779	6.958	EPSD	COSMIC;CCLE	8.148	Loss
CMGC_CDK_CDK2_CDK2_ST	Q01196	RUNX1	P24941	CDK2	S21	P22Q	22	Missense	proximal	1	no	16.779	8.867	EPSD	COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	Q01196	RUNX1	P24941	CDK2	S21	E27K	27	Missense	distal	6	no	16.779	16.790	EPSD	COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	Q01196	RUNX1	P24941	CDK2	S21	T14M	14	Missense	distal	-7	no	16.779	17.283	EPSD	COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	Q01196	RUNX1	P24941	CDK2	S46	S50R	50	Missense	distal	4	no	8.150	8.016	EPSD	COSMIC	8.148	Loss
CMGC_CDK_CDK2_CDK2_ST	Q01196	RUNX1	P24941	CDK2	S46	S50G	50	Missense	distal	4	no	8.150	8.016	EPSD	COSMIC	8.148	Loss
CMGC_CDK_CDK2_CDK2_ST	Q01196	RUNX1	P24941	CDK2	S46	G42R	42	Missense	distal	-4	no	8.150	8.225	EPSD	COSMIC;CCLE	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	Q01196	RUNX1	P24941	CDK2	S46	D48Y	48	Missense	proximal	2	no	8.150	8.210	EPSD	COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	Q01196	RUNX1	P24941	CDK2	S46	R49H	49	Missense	distal	3	no	8.150	7.453	EPSD	COSMIC;CCLE	8.148	Loss
CMGC_CDK_CDK2_CDK2_ST	Q01196	RUNX1	P24941	CDK2	S46	A41T	41	Missense	distal	-5	no	8.150	8.123	EPSD	COSMIC	8.148	Loss
CMGC_CDK_CDK2_CDK2_ST	Q01196	RUNX1	P24941	CDK2	S46	A39V	39	Missense	distal	-7	no	8.150	8.005	EPSD	COSMIC	8.148	Loss
CMGC_CDK_CDK2_CDK2_ST	Q01196	RUNX1	P24941	CDK2	S46	L44M	44	Missense	proximal	-2	no	8.150	6.289	EPSD	COSMIC	8.148	Loss
CMGC_CDK_CDK2_CDK2_ST	Q01196	RUNX1	P24941	CDK2	S46	A41V	41	Missense	distal	-5	no	8.150	8.156	EPSD	COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	Q01196	RUNX1	P24941	CDK2	S46	E53D	53	Missense	distal	7	no	8.150	8.792	EPSD	COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	Q01196	RUNX1	P24941	CDK2	S67	L71M	71	Missense	distal	4	no	12.917	12.384	EPSD	COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	Q01196	RUNX1	P24941	CDK2	S67	V63A	63	Missense	distal	-4	no	12.917	12.907	EPSD	COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	Q01196	RUNX1	P24941	CDK2	S67	L62R	62	Missense	distal	-5	no	12.917	12.952	EPSD	COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	Q01196	RUNX1	P24941	CDK2	S67	F70Y	70	Missense	distal	3	no	12.917	12.213	EPSD	COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	Q01196	RUNX1	P24941	CDK2	S67	F70L	70	Missense	distal	3	no	12.917	12.575	EPSD	COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	Q01196	RUNX1	P24941	CDK2	S67	T65A	65	Missense	proximal	-2	no	12.917	12.967	EPSD	COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	Q01196	RUNX1	P24941	CDK2	S67	S73F	73	Missense	distal	6	no	12.917	12.898	EPSD	COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	Q01196	RUNX1	P24941	CDK2	S67	D66N	66	Missense	proximal	-1	no	12.917	12.088	EPSD	COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	Q01196	RUNX1	P24941	CDK2	S67	C72Y	72	Missense	distal	5	no	12.917	12.757	EPSD	COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	Q01196	RUNX1	P24941	CDK2	S67	N69S	69	Missense	proximal	2	no	12.917	13.054	EPSD	COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	Q01196	RUNX1	P24941	CDK2	S67	P68L	68	Missense	proximal	1	no	12.917	3.096	EPSD	COSMIC	8.148	Loss
CMGC_CDK_CDK2_CDK2_ST	Q01196	RUNX1	P24941	CDK2	S67	S67I	67	Missense	central	0	yes	12.917	0.000	EPSD	COSMIC	8.148	Loss
CMGC_CDK_CDK2_CDK2_ST	Q01196	RUNX1	P24941	CDK2	S67	E61K	61	Missense	distal	-6	no	12.917	12.915	EPSD	COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	Q01196	RUNX1	P24941	CDK2	S67	S67R	67	Missense	central	0	yes	12.917	0.000	EPSD	COSMIC;CCLE	8.148	Loss
CMGC_CDK_CDK2_CDK2_ST	Q01196	RUNX1	P24941	CDK2	S67	S73C	73	Missense	distal	6	no	12.917	12.902	EPSD	COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	Q01196	RUNX1	P24941	CDK2	S67	F70S	70	Missense	distal	3	no	12.917	12.992	EPSD	COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	Q01196	RUNX1	P24941	CDK2	S67	D66Y	66	Missense	proximal	-1	no	12.917	12.601	EPSD	COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	Q01196	RUNX1	P24941	CDK2	T84	L85P	85	Missense	proximal	1	no	3.469	13.290	EPSD	COSMIC	8.148	Gain
CMGC_CDK_CDK2_CDK2_ST	Q01196	RUNX1	P24941	CDK2	T147	L148P	148	Missense	proximal	1	no	1.648	11.469	EPSD	COSMIC	8.148	Gain
CMGC_CDK_CDK2_CDK2_ST	Q01196	RUNX1	P24941	CDK2	S212	A208G	208	Missense	distal	-4	no	14.217	13.958	EPSD	COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	Q01196	RUNX1	P24941	CDK2	S212	S212L	212	Missense	central	0	yes	14.217	0.000	EPSD	COSMIC	8.148	Loss
CMGC_CDK_CDK2_CDK2_ST	Q01196	RUNX1	P24941	CDK2	S212	R205Q	205	Missense	distal	-7	no	14.217	13.831	EPSD	COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	Q01196	RUNX1	P24941	CDK2	S212	R205L	205	Missense	distal	-7	no	14.217	13.879	EPSD	COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	Q01196	RUNX1	P24941	CDK2	S212	R210K	210	Missense	proximal	-2	no	14.217	14.939	EPSD	COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	Q01196	RUNX1	P24941	CDK2	S212	T219M	219	Missense	distal	7	no	14.217	15.066	EPSD	COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	Q01196	RUNX1	P24941	CDK2	S212	A208V	208	Missense	distal	-4	no	14.217	14.228	EPSD	COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	Q01196	RUNX1	P24941	CDK2	S212	R205W	205	Missense	distal	-7	no	14.217	14.388	EPSD	COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	Q01196	RUNX1	P24941	CDK2	S212	P218S	218	Missense	distal	6	no	14.217	14.219	EPSD	COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	Q01196	RUNX1	P24941	CDK2	S212	P216L	216	Missense	distal	4	no	14.217	14.329	EPSD	COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	Q01196	RUNX1	P24941	CDK2	S212	A208T	208	Missense	distal	-4	no	14.217	14.443	EPSD	COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	Q01196	RUNX1	P24941	CDK2	S212	A217V	217	Missense	distal	5	no	14.217	14.174	EPSD	COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	Q01196	RUNX1	P24941	CDK2	S212	R206H	206	Missense	distal	-6	no	14.217	14.219	EPSD	COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	Q01196	RUNX1	P24941	CDK2	S212	P218L	218	Missense	distal	6	no	14.217	14.219	EPSD	COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	Q01196	RUNX1	P24941	CDK2	S212	V211A	211	Missense	proximal	-1	no	14.217	13.990	EPSD	COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	Q01196	RUNX1	P24941	CDK2	S212	M209I	209	Missense	distal	-3	no	14.217	13.869	EPSD	COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	Q01196	RUNX1	P24941	CDK2	T219	L226F	226	Missense	distal	7	no	12.637	13.308	EPSD	COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	Q01196	RUNX1	P24941	CDK2	T219	S212L	212	Missense	distal	-7	no	12.637	12.822	EPSD	COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	Q01196	RUNX1	P24941	CDK2	T219	A224V	224	Missense	distal	5	no	12.637	12.594	EPSD	COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	Q01196	RUNX1	P24941	CDK2	T219	R223C	223	Missense	distal	4	no	12.637	12.010	EPSD	COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	Q01196	RUNX1	P24941	CDK2	T219	T219M	219	Missense	central	0	yes	12.637	0.000	EPSD	COSMIC	8.148	Loss
CMGC_CDK_CDK2_CDK2_ST	Q01196	RUNX1	P24941	CDK2	T219	S225F	225	Missense	distal	6	no	12.637	12.617	EPSD	COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	Q01196	RUNX1	P24941	CDK2	T219	P218S	218	Missense	proximal	-1	no	12.637	12.166	EPSD	COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	Q01196	RUNX1	P24941	CDK2	T219	A224T	224	Missense	distal	5	no	12.637	12.601	EPSD	COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	Q01196	RUNX1	P24941	CDK2	T219	P216L	216	Missense	distal	-3	no	12.637	12.566	EPSD	COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	Q01196	RUNX1	P24941	CDK2	T219	A217V	217	Missense	proximal	-2	no	12.637	11.971	EPSD	COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	Q01196	RUNX1	P24941	CDK2	T219	R223P	223	Missense	distal	4	no	12.637	12.757	EPSD	COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	Q01196	RUNX1	P24941	CDK2	T219	P218L	218	Missense	proximal	-1	no	12.637	12.457	EPSD	COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	Q01196	RUNX1	P24941	CDK2	T219	R223H	223	Missense	distal	4	no	12.637	12.519	EPSD	COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	Q01196	RUNX1	P24941	CDK2	T219	P222S	222	Missense	distal	3	no	12.637	12.671	EPSD	COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	Q01196	RUNX1	P24941	CDK2	S225	R223P	223	Missense	proximal	-2	no	7.623	8.858	EPSD	COSMIC	8.148	Gain
CMGC_CDK_CDK2_CDK2_ST	Q01196	RUNX1	P24941	CDK2	S249	T243I	243	Missense	distal	-6	no	12.126	12.128	EPSD	COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	Q01196	RUNX1	P24941	CDK2	S249	P250L	250	Missense	proximal	1	no	12.126	2.305	EPSD	COSMIC	8.148	Loss
CMGC_CDK_CDK2_CDK2_ST	Q01196	RUNX1	P24941	CDK2	S249	P251L	251	Missense	proximal	2	no	12.126	12.019	EPSD	COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	Q01196	RUNX1	P24941	CDK2	S266	S268F	268	Missense	proximal	2	no	13.133	13.318	EPSD	COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	Q01196	RUNX1	P24941	CDK2	S266	P267S	267	Missense	proximal	1	no	13.133	1.868	EPSD	COSMIC	8.148	Loss
CMGC_CDK_CDK2_CDK2_ST	Q01196	RUNX1	P24941	CDK2	S266	T273M	273	Missense	distal	7	no	13.133	13.982	EPSD	COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	Q01196	RUNX1	P24941	CDK2	S266	G262R	262	Missense	distal	-4	no	13.133	13.208	EPSD	COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	Q01196	RUNX1	P24941	CDK2	S266	P271Q	271	Missense	distal	5	no	13.133	13.093	EPSD	COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	Q01196	RUNX1	P24941	CDK2	S266	Y260F	260	Missense	distal	-6	no	13.133	13.138	EPSD	COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	Q01196	RUNX1	P24941	CDK2	S266	P271S	271	Missense	distal	5	no	13.133	13.032	EPSD	COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	Q01196	RUNX1	P24941	CDK2	S266	A265S	265	Missense	proximal	-1	no	13.133	12.933	EPSD	COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	Q01196	RUNX1	P24941	CDK2	S266	L261P	261	Missense	distal	-5	no	13.133	13.122	EPSD	COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	Q01196	RUNX1	P24941	CDK2	S266	A272G	272	Missense	distal	6	no	13.133	13.126	EPSD	COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	Q01196	RUNX1	P24941	CDK2	T273	P277L	277	Missense	distal	4	no	14.349	14.461	EPSD	COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	Q01196	RUNX1	P24941	CDK2	T273	S268F	268	Missense	distal	-5	no	14.349	14.466	EPSD	COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	Q01196	RUNX1	P24941	CDK2	T273	P267S	267	Missense	distal	-6	no	14.349	14.348	EPSD	COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	Q01196	RUNX1	P24941	CDK2	T273	S276L	276	Missense	distal	3	no	14.349	13.932	EPSD	COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	Q01196	RUNX1	P24941	CDK2	T273	T273M	273	Missense	central	0	yes	14.349	0.000	EPSD	COSMIC	8.148	Loss
CMGC_CDK_CDK2_CDK2_ST	Q01196	RUNX1	P24941	CDK2	T273	P271Q	271	Missense	proximal	-2	no	14.349	13.782	EPSD	COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	Q01196	RUNX1	P24941	CDK2	T273	P271S	271	Missense	proximal	-2	no	14.349	13.698	EPSD	COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	Q01196	RUNX1	P24941	CDK2	T273	R279C	279	Missense	distal	6	no	14.349	14.352	EPSD	COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	Q01196	RUNX1	P24941	CDK2	T273	A272G	272	Missense	proximal	-1	no	14.349	15.668	EPSD	COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	Q01196	RUNX1	P24941	CDK2	T273	R279P	279	Missense	distal	6	no	14.349	14.365	EPSD	COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	Q01196	RUNX1	P24941	CDK2	S276	P277L	277	Missense	proximal	1	no	17.102	7.281	PhosphoSitePlus;EPSD	COSMIC	8.148	Loss
CMGC_CDK_CDK2_CDK2_ST	Q01196	RUNX1	P24941	CDK2	S276	S276L	276	Missense	central	0	yes	17.102	0.000	PhosphoSitePlus;EPSD	COSMIC	8.148	Loss
CMGC_CDK_CDK2_CDK2_ST	Q01196	RUNX1	P24941	CDK2	S276	T273M	273	Missense	distal	-3	no	17.102	17.510	PhosphoSitePlus;EPSD	COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	Q01196	RUNX1	P24941	CDK2	S276	G282S	282	Missense	distal	6	no	17.102	17.114	PhosphoSitePlus;EPSD	COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	Q01196	RUNX1	P24941	CDK2	S276	P271S	271	Missense	distal	-5	no	17.102	17.058	PhosphoSitePlus;EPSD	COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	Q01196	RUNX1	P24941	CDK2	S276	R279C	279	Missense	distal	3	no	17.102	10.738	PhosphoSitePlus;EPSD	COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	Q01196	RUNX1	P24941	CDK2	S276	A272G	272	Missense	distal	-4	no	17.102	16.843	PhosphoSitePlus;EPSD	COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	Q01196	RUNX1	P24941	CDK2	S276	R279P	279	Missense	distal	3	no	17.102	15.383	PhosphoSitePlus;EPSD	COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	Q01196	RUNX1	P24941	CDK2	S304	P298S	298	Missense	distal	-6	no	11.112	11.111	EPSD	COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	Q01196	RUNX1	P24941	CDK2	S304	D305H	305	Missense	proximal	1	no	11.112	12.597	EPSD	COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	Q01196	RUNX1	P24941	CDK2	S304	D299N	299	Missense	distal	-5	no	11.112	11.074	EPSD	COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	Q01196	RUNX1	P24941	CDK2	S304	P310L	310	Missense	distal	6	no	11.112	11.113	EPSD	COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	Q01196	RUNX1	P24941	CDK2	S304	T301I	301	Missense	distal	-3	no	11.112	11.171	EPSD	COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	Q01196	RUNX1	P24941	CDK2	S304	D305A	305	Missense	proximal	1	no	11.112	4.952	EPSD	COSMIC	8.148	Loss
CMGC_CDK_CDK2_CDK2_ST	Q01196	RUNX1	P24941	CDK2	S304	R307C	307	Missense	distal	3	no	11.112	4.748	EPSD	COSMIC	8.148	Loss
CMGC_CDK_CDK2_CDK2_ST	Q01196	RUNX1	P24941	CDK2	S304	A297V	297	Missense	distal	-7	no	11.112	10.967	EPSD	COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	Q01196	RUNX1	P24941	CDK2	S304	A302V	302	Missense	proximal	-2	no	11.112	10.446	EPSD	COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	Q01196	RUNX1	P24941	CDK2	S304	A311V	311	Missense	distal	7	no	11.112	10.986	EPSD	COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	Q01196	RUNX1	P24941	CDK2	S304	R307H	307	Missense	distal	3	no	11.112	10.415	EPSD	COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	Q01196	RUNX1	P24941	CDK2	S329	F326S	326	Missense	distal	-3	no	15.949	15.857	EPSD	COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	Q01196	RUNX1	P24941	CDK2	S329	P323S	323	Missense	distal	-6	no	15.949	15.948	EPSD	COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	Q01196	RUNX1	P24941	CDK2	S329	P332L	332	Missense	distal	3	no	15.949	15.565	EPSD	COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	Q01196	RUNX1	P24941	CDK2	T331	F326S	326	Missense	distal	-5	no	14.424	14.307	EPSD	COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	Q01196	RUNX1	P24941	CDK2	T331	G338V	338	Missense	distal	7	no	14.424	14.012	EPSD	COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	Q01196	RUNX1	P24941	CDK2	T331	P332L	332	Missense	proximal	1	no	14.424	4.603	EPSD	COSMIC	8.148	Loss
CMGC_CDK_CDK2_CDK2_ST	Q01196	RUNX1	P24941	CDK2	T331	S335L	335	Missense	distal	4	no	14.424	14.522	EPSD	COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	Q01196	RUNX1	P24941	CDK2	S373	G367D	367	Missense	distal	-6	no	11.242	11.238	EPSD	COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	Q01196	RUNX1	P24941	CDK2	S373	S373L	373	Missense	central	0	yes	11.242	0.000	EPSD	COSMIC	8.148	Loss
CMGC_CDK_CDK2_CDK2_ST	Q01196	RUNX1	P24941	CDK2	S373	Q370R	370	Missense	distal	-3	no	11.242	11.373	EPSD	COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	Q01196	RUNX1	P24941	CDK2	S373	P368M	368	Missense	distal	-5	no	11.242	11.349	EPSD	COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	Q01196	RUNX1	P24941	CDK2	S373	Y380C	380	Missense	distal	7	no	11.242	11.614	EPSD	COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	Q01196	RUNX1	P24941	CDK2	S373	S375F	375	Missense	proximal	2	no	11.242	11.427	EPSD	COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	Q01196	RUNX1	P24941	CDK2	S373	G366A	366	Missense	distal	-7	no	11.242	11.082	EPSD	COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	Q01196	RUNX1	P24941	CDK2	S373	F369I	369	Missense	distal	-4	no	11.242	11.699	EPSD	COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	Q01196	RUNX1	P24941	CDK2	S373	P368L	368	Missense	distal	-5	no	11.242	11.254	EPSD	COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	Q01196	RUNX1	P24941	CDK2	S397	G393A	393	Missense	distal	-4	no	14.098	14.357	EPSD	COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	Q01196	RUNX1	P24941	CDK2	S397	E395K	395	Missense	proximal	-2	no	14.098	14.699	EPSD	COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	Q01196	RUNX1	P24941	CDK2	S397	V392G	392	Missense	distal	-5	no	14.098	14.146	EPSD	COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	Q01196	RUNX1	P24941	CDK2	S397	S397L	397	Missense	central	0	yes	14.098	0.000	EPSD	COSMIC	8.148	Loss
CMGC_CDK_CDK2_CDK2_ST	Q01196	RUNX1	P24941	CDK2	S397	P398Q	398	Missense	proximal	1	no	14.098	6.186	EPSD	COSMIC	8.148	Loss
CMGC_CDK_CDK2_CDK2_ST	Q01196	RUNX1	P24941	CDK2	S397	P398L	398	Missense	proximal	1	no	14.098	4.277	EPSD	COSMIC	8.148	Loss
CMGC_CDK_CDK2_CDK2_ST	Q01196	RUNX1	P24941	CDK2	S397	R396H	396	Missense	proximal	-1	no	14.098	13.646	EPSD	COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	Q01196	RUNX1	P24941	CDK2	S397	G394S	394	Missense	distal	-3	no	14.098	14.089	EPSD	COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	Q01196	RUNX1	P24941	CDK2	S397	G393D	393	Missense	distal	-4	no	14.098	14.943	EPSD	COSMIC;CCLE	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	Q01196	RUNX1	P24941	CDK2	S397	R400H	400	Missense	distal	3	no	14.098	13.401	EPSD	COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	Q01196	RUNX1	P24941	CDK2	S397	P399T	399	Missense	proximal	2	no	14.098	13.920	EPSD	COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	Q01196	RUNX1	P24941	CDK2	S397	R396P	396	Missense	proximal	-1	no	14.098	13.527	EPSD	COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	Q01196	RUNX1	P24941	CDK2	S397	S390F	390	Missense	distal	-7	no	14.098	14.649	EPSD	COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	Q01196	RUNX1	P24941	CDK2	S397	S397P	397	Missense	central	0	yes	14.098	0.000	EPSD	COSMIC	8.148	Loss
CMGC_CDK_CDK2_CDK2_ST	Q01196	RUNX1	P24941	CDK2	S397	R396C	396	Missense	proximal	-1	no	14.098	13.400	EPSD	COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	Q01196	RUNX1	P24941	CDK2	S397	S397A	397	Missense	central	0	yes	14.098	0.000	EPSD	COSMIC	8.148	Loss
CMGC_CDK_CDK2_CDK2_ST	Q01196	RUNX1	P24941	CDK2	S431	E429D	429	Missense	proximal	-2	no	7.365	8.345	EPSD	COSMIC	8.148	Gain
CMGC_CDK_CDK2_CDK2_ST	Q01196	RUNX1	P24941	CDK2	S435	E429D	429	Missense	distal	-6	no	14.732	14.728	EPSD	COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	Q01196	RUNX1	P24941	CDK2	S435	A440V	440	Missense	distal	5	no	14.732	14.689	EPSD	COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	Q01196	RUNX1	P24941	CDK2	S435	S433N	433	Missense	proximal	-2	no	14.732	14.040	EPSD	COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	Q01196	RUNX1	P24941	CDK2	S435	P436C	436	Missense	proximal	1	no	14.732	-4.197	EPSD	COSMIC	8.148	Loss
CMGC_CDK_CDK2_CDK2_ST	Q01196	RUNX1	P24941	CDK2	S435	S442F	442	Missense	distal	7	no	14.732	15.586	EPSD	COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	Q01196	RUNX1	P24941	CDK2	S435	E429K	429	Missense	distal	-6	no	14.732	14.730	EPSD	COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	Q01196	RUNX1	P24941	CDK2	S435	S431G	431	Missense	distal	-4	no	14.732	14.060	EPSD	COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	Q01196	RUNX1	P24941	CDK2	S435	M439L	439	Missense	distal	4	no	14.732	15.265	EPSD	COSMIC;CCLE	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	Q01196	RUNX1	P24941	CDK2	S435	M439T	439	Missense	distal	4	no	14.732	15.436	EPSD	COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	P48200	IREB2	P24941	CDK2	S157	S157F	157	Missense	central	0	yes	18.378	0.000	PhosphoSitePlus	COSMIC	8.148	Loss
CMGC_CDK_CDK2_CDK2_ST	P48200	IREB2	P24941	CDK2	T777	L771F	771	Missense	distal	-6	no	14.247	14.251	EPSD	COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	P48200	IREB2	P24941	CDK2	T777	T777I	777	Missense	central	0	yes	14.247	0.000	EPSD	COSMIC	8.148	Loss
CMGC_CDK_CDK2_CDK2_ST	P30050	RPL12	P24941	CDK2	S157	I152T	152	Missense	distal	-5	no	9.198	9.157	EPSD	COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	P30050	RPL12	P24941	CDK2	S157	I151V	151	Missense	distal	-6	no	9.198	9.197	EPSD	COSMIC;GDSC;CCLE	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	P30050	RPL12	P24941	CDK2	S157	V160L	160	Missense	distal	3	no	9.198	8.206	EPSD	COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	P30050	RPL12	P24941	CDK2	S157	D153V	153	Missense	distal	-4	no	9.198	8.623	EPSD	COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	Q9NYF8	BCLAF1	P24941	CDK2	S10	S11P	11	Missense	proximal	1	no	-0.525	10.741	EPSD	COSMIC	8.148	Gain
CMGC_CDK_CDK2_CDK2_ST	Q9NYF8	BCLAF1	P24941	CDK2	S36	R37H	37	Missense	proximal	1	no	7.991	11.031	EPSD	COSMIC	8.148	Gain
CMGC_CDK_CDK2_CDK2_ST	Q9NYF8	BCLAF1	P24941	CDK2	S36	S38F	38	Missense	proximal	2	no	7.991	8.175	EPSD	COSMIC	8.148	Gain
CMGC_CDK_CDK2_CDK2_ST	Q9NYF8	BCLAF1	P24941	CDK2	S38	R39H	39	Missense	proximal	1	no	7.368	10.407	EPSD	COSMIC	8.148	Gain
CMGC_CDK_CDK2_CDK2_ST	Q9NYF8	BCLAF1	P24941	CDK2	S44	R37H	37	Missense	distal	-7	no	8.178	7.957	EPSD	COSMIC	8.148	Loss
CMGC_CDK_CDK2_CDK2_ST	Q9NYF8	BCLAF1	P24941	CDK2	S44	R49H	49	Missense	distal	5	no	8.178	8.149	EPSD	COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	Q9NYF8	BCLAF1	P24941	CDK2	S44	R49C	49	Missense	distal	5	no	8.178	8.305	EPSD	COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	Q9NYF8	BCLAF1	P24941	CDK2	S44	R45P	45	Missense	proximal	1	no	8.178	17.976	EPSD	COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	Q9NYF8	BCLAF1	P24941	CDK2	S44	S46I	46	Missense	proximal	2	no	8.178	8.088	EPSD	COSMIC	8.148	Loss
CMGC_CDK_CDK2_CDK2_ST	Q9NYF8	BCLAF1	P24941	CDK2	S44	R47T	47	Missense	distal	3	no	8.178	6.345	EPSD	COSMIC	8.148	Loss
CMGC_CDK_CDK2_CDK2_ST	Q9NYF8	BCLAF1	P24941	CDK2	S44	R45M	45	Missense	proximal	1	no	8.178	-8.836	EPSD	COSMIC	8.148	Loss
CMGC_CDK_CDK2_CDK2_ST	Q9NYF8	BCLAF1	P24941	CDK2	S44	R49T	49	Missense	distal	5	no	8.178	8.046	EPSD	COSMIC	8.148	Loss
CMGC_CDK_CDK2_CDK2_ST	Q9NYF8	BCLAF1	P24941	CDK2	S44	R37T	37	Missense	distal	-7	no	8.178	7.831	EPSD	COSMIC	8.148	Loss
CMGC_CDK_CDK2_CDK2_ST	Q9NYF8	BCLAF1	P24941	CDK2	S44	D50V	50	Missense	distal	6	no	8.178	8.191	EPSD	COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	Q9NYF8	BCLAF1	P24941	CDK2	S44	S48I	48	Missense	distal	4	no	8.178	8.136	EPSD	COSMIC	8.148	Loss
CMGC_CDK_CDK2_CDK2_ST	Q9NYF8	BCLAF1	P24941	CDK2	S44	R47P	47	Missense	distal	3	no	8.178	6.459	EPSD	COSMIC	8.148	Loss
CMGC_CDK_CDK2_CDK2_ST	Q9NYF8	BCLAF1	P24941	CDK2	S44	R37K	37	Missense	distal	-7	no	8.178	7.787	EPSD	COSMIC	8.148	Loss
CMGC_CDK_CDK2_CDK2_ST	Q9NYF8	BCLAF1	P24941	CDK2	S44	S38F	38	Missense	distal	-6	no	8.178	8.183	EPSD	COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	Q9NYF8	BCLAF1	P24941	CDK2	S44	R37S	37	Missense	distal	-7	no	8.178	7.654	EPSD	COSMIC	8.148	Loss
CMGC_CDK_CDK2_CDK2_ST	Q9NYF8	BCLAF1	P24941	CDK2	S46	R45M	45	Missense	proximal	-1	no	8.094	8.573	EPSD	COSMIC	8.148	Gain
CMGC_CDK_CDK2_CDK2_ST	Q9NYF8	BCLAF1	P24941	CDK2	S46	D50V	50	Missense	distal	4	no	8.094	8.386	EPSD	COSMIC	8.148	Gain
CMGC_CDK_CDK2_CDK2_ST	Q9NYF8	BCLAF1	P24941	CDK2	S46	R47P	47	Missense	proximal	1	no	8.094	17.893	EPSD	COSMIC	8.148	Gain
CMGC_CDK_CDK2_CDK2_ST	Q9NYF8	BCLAF1	P24941	CDK2	S48	R49H	49	Missense	proximal	1	no	7.745	10.784	EPSD	COSMIC	8.148	Gain
CMGC_CDK_CDK2_CDK2_ST	Q9NYF8	BCLAF1	P24941	CDK2	S48	S46I	46	Missense	proximal	-2	no	7.745	8.242	EPSD	COSMIC	8.148	Gain
CMGC_CDK_CDK2_CDK2_ST	Q9NYF8	BCLAF1	P24941	CDK2	S104	R107C	107	Missense	distal	3	no	16.166	9.802	EPSD	COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	Q9NYF8	BCLAF1	P24941	CDK2	S104	R107S	107	Missense	distal	3	no	16.166	14.482	EPSD	COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	Q9NYF8	BCLAF1	P24941	CDK2	S104	S110Y	110	Missense	distal	6	no	16.166	16.157	EPSD	COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	Q9NYF8	BCLAF1	P24941	CDK2	S104	R111W	111	Missense	distal	7	no	16.166	16.565	EPSD	COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	Q9NYF8	BCLAF1	P24941	CDK2	S104	R107L	107	Missense	distal	3	no	16.166	14.064	EPSD	COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	Q9NYF8	BCLAF1	P24941	CDK2	S104	R99T	99	Missense	distal	-5	no	16.166	16.118	EPSD	COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	Q9NYF8	BCLAF1	P24941	CDK2	S104	N98D	98	Missense	distal	-6	no	16.166	16.165	EPSD	COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	Q9NYF8	BCLAF1	P24941	CDK2	S104	S102F	102	Missense	proximal	-2	no	16.166	15.704	EPSD	COSMIC;GDSC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	Q9NYF8	BCLAF1	P24941	CDK2	S104	H101N	101	Missense	distal	-3	no	16.166	16.041	EPSD	COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	Q9NYF8	BCLAF1	P24941	CDK2	S114	R107C	107	Missense	distal	-7	no	14.129	14.056	EPSD	COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	Q9NYF8	BCLAF1	P24941	CDK2	S114	R107S	107	Missense	distal	-7	no	14.129	13.606	EPSD	COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	Q9NYF8	BCLAF1	P24941	CDK2	S114	S110Y	110	Missense	distal	-4	no	14.129	14.240	EPSD	COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	Q9NYF8	BCLAF1	P24941	CDK2	S114	R111W	111	Missense	distal	-3	no	14.129	14.210	EPSD	COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	Q9NYF8	BCLAF1	P24941	CDK2	S114	R107L	107	Missense	distal	-7	no	14.129	13.791	EPSD	COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	Q9NYF8	BCLAF1	P24941	CDK2	S114	R113W	113	Missense	proximal	-1	no	14.129	14.683	EPSD	COSMIC;GDSC;CCLE	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	Q9NYF8	BCLAF1	P24941	CDK2	S114	V120I	120	Missense	distal	6	no	14.129	14.131	EPSD	COSMIC;GDSC;CCLE	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	Q9NYF8	BCLAF1	P24941	CDK2	S138	R140S	140	Missense	proximal	2	no	16.318	16.226	EPSD	COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	Q9NYF8	BCLAF1	P24941	CDK2	S138	R131W	131	Missense	distal	-7	no	16.318	16.489	EPSD	COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	Q9NYF8	BCLAF1	P24941	CDK2	S138	R145H	145	Missense	distal	7	no	16.318	15.960	EPSD	COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	Q9NYF8	BCLAF1	P24941	CDK2	S148	P149S	149	Missense	proximal	1	no	14.186	2.920	EPSD	COSMIC	8.148	Loss
CMGC_CDK_CDK2_CDK2_ST	Q9NYF8	BCLAF1	P24941	CDK2	S148	P154S	154	Missense	distal	6	no	14.186	14.188	EPSD	COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	Q9NYF8	BCLAF1	P24941	CDK2	S148	Y150C	150	Missense	proximal	2	no	14.186	14.274	EPSD	COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	Q9NYF8	BCLAF1	P24941	CDK2	S148	R145H	145	Missense	distal	-3	no	14.186	14.144	EPSD	COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	Q9NYF8	BCLAF1	P24941	CDK2	S148	Y150N	150	Missense	proximal	2	no	14.186	14.058	EPSD	COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	Q9NYF8	BCLAF1	P24941	CDK2	S153	P149S	149	Missense	distal	-4	no	12.146	12.500	EPSD	COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	Q9NYF8	BCLAF1	P24941	CDK2	S153	P154S	154	Missense	proximal	1	no	12.146	0.880	EPSD	COSMIC	8.148	Loss
CMGC_CDK_CDK2_CDK2_ST	Q9NYF8	BCLAF1	P24941	CDK2	S153	Y150C	150	Missense	distal	-3	no	12.146	12.134	EPSD	COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	Q9NYF8	BCLAF1	P24941	CDK2	S153	S156Y	156	Missense	distal	3	no	12.146	11.366	EPSD	COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	Q9NYF8	BCLAF1	P24941	CDK2	S153	Y150N	150	Missense	distal	-3	no	12.146	12.052	EPSD	COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	Q9NYF8	BCLAF1	P24941	CDK2	S153	S148T	148	Missense	distal	-5	no	12.146	12.189	EPSD	COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	Q9NYF8	BCLAF1	P24941	CDK2	S177	P178S	178	Missense	proximal	1	no	14.882	3.616	EPSD	COSMIC	8.148	Loss
CMGC_CDK_CDK2_CDK2_ST	Q9NYF8	BCLAF1	P24941	CDK2	S177	S181G	181	Missense	distal	4	no	14.882	14.749	EPSD	COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	Q9NYF8	BCLAF1	P24941	CDK2	S177	P178Q	178	Missense	proximal	1	no	14.882	6.971	EPSD	COSMIC	8.148	Loss
CMGC_CDK_CDK2_CDK2_ST	Q9NYF8	BCLAF1	P24941	CDK2	S177	E176G	176	Missense	proximal	-1	no	14.882	15.146	EPSD	COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	Q9NYF8	BCLAF1	P24941	CDK2	S177	P178L	178	Missense	proximal	1	no	14.882	5.061	EPSD	COSMIC	8.148	Loss
CMGC_CDK_CDK2_CDK2_ST	Q9NYF8	BCLAF1	P24941	CDK2	T208	S209P	209	Missense	proximal	1	no	-0.163	11.103	EPSD	COSMIC	8.148	Gain
CMGC_CDK_CDK2_CDK2_ST	Q9NYF8	BCLAF1	P24941	CDK2	S222	S222N	222	Missense	central	0	yes	14.360	0.000	EPSD	COSMIC;GDSC;CCLE	8.148	Loss
CMGC_CDK_CDK2_CDK2_ST	Q9NYF8	BCLAF1	P24941	CDK2	S222	R224T	224	Missense	proximal	2	no	14.360	14.024	EPSD	COSMIC;GDSC;CCLE	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	Q9NYF8	BCLAF1	P24941	CDK2	S225	S228L	228	Missense	distal	3	no	14.937	14.519	EPSD	COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	Q9NYF8	BCLAF1	P24941	CDK2	S225	S222N	222	Missense	distal	-3	no	14.937	14.862	EPSD	COSMIC;GDSC;CCLE	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	Q9NYF8	BCLAF1	P24941	CDK2	S225	S222T	222	Missense	distal	-3	no	14.937	14.802	EPSD	COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	Q9NYF8	BCLAF1	P24941	CDK2	S225	R224T	224	Missense	proximal	-1	no	14.937	14.103	EPSD	COSMIC;GDSC;CCLE	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	Q9NYF8	BCLAF1	P24941	CDK2	S225	I232V	232	Missense	distal	7	no	14.937	15.138	EPSD	COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	Q9NYF8	BCLAF1	P24941	CDK2	S228	S228L	228	Missense	central	0	yes	12.823	0.000	EPSD	COSMIC	8.148	Loss
CMGC_CDK_CDK2_CDK2_ST	Q9NYF8	BCLAF1	P24941	CDK2	S228	R224T	224	Missense	distal	-4	no	12.823	13.232	EPSD	COSMIC;GDSC;CCLE	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	Q9NYF8	BCLAF1	P24941	CDK2	S228	A233T	233	Missense	distal	5	no	12.823	12.787	EPSD	COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	Q9NYF8	BCLAF1	P24941	CDK2	S228	I232V	232	Missense	distal	4	no	12.823	13.078	EPSD	COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	Q9NYF8	BCLAF1	P24941	CDK2	S230	S228L	228	Missense	proximal	-2	no	11.833	12.260	EPSD	COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	Q9NYF8	BCLAF1	P24941	CDK2	S230	R224T	224	Missense	distal	-6	no	11.833	11.831	EPSD	COSMIC;GDSC;CCLE	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	Q9NYF8	BCLAF1	P24941	CDK2	S230	A233T	233	Missense	distal	3	no	11.833	12.231	EPSD	COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	Q9NYF8	BCLAF1	P24941	CDK2	S230	I232V	232	Missense	proximal	2	no	11.833	11.979	EPSD	COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	Q9NYF8	BCLAF1	P24941	CDK2	T234	S228L	228	Missense	distal	-6	no	13.445	13.446	EPSD	COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	Q9NYF8	BCLAF1	P24941	CDK2	T234	A233T	233	Missense	proximal	-1	no	13.445	13.452	EPSD	COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	Q9NYF8	BCLAF1	P24941	CDK2	T234	I232V	232	Missense	proximal	-2	no	13.445	12.949	EPSD	COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	Q9NYF8	BCLAF1	P24941	CDK2	T257	H261L	261	Missense	distal	4	no	11.189	11.538	EPSD	COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	Q9NYF8	BCLAF1	P24941	CDK2	S268	H261L	261	Missense	distal	-7	no	15.574	15.457	EPSD	COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	Q9NYF8	BCLAF1	P24941	CDK2	S268	S274F	274	Missense	distal	6	no	15.574	15.555	EPSD	COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	Q9NYF8	BCLAF1	P24941	CDK2	S268	G273V	273	Missense	distal	5	no	15.574	15.415	EPSD	COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	Q9NYF8	BCLAF1	P24941	CDK2	S268	G273W	273	Missense	distal	5	no	15.574	15.720	EPSD	COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	Q9NYF8	BCLAF1	P24941	CDK2	S285	S282G	282	Missense	distal	-3	no	14.602	14.610	EPSD	COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	Q9NYF8	BCLAF1	P24941	CDK2	S285	G278V	278	Missense	distal	-7	no	14.602	14.297	EPSD	COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	Q9NYF8	BCLAF1	P24941	CDK2	S285	G278E	278	Missense	distal	-7	no	14.602	14.368	EPSD	COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	Q9NYF8	BCLAF1	P24941	CDK2	S285	P291L	291	Missense	distal	6	no	14.602	14.603	EPSD	COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	Q9NYF8	BCLAF1	P24941	CDK2	S290	P291L	291	Missense	proximal	1	no	13.271	3.450	EPSD	COSMIC	8.148	Loss
CMGC_CDK_CDK2_CDK2_ST	Q9NYF8	BCLAF1	P24941	CDK2	S300	P301S	301	Missense	proximal	1	no	17.632	6.366	EPSD	COSMIC	8.148	Loss
CMGC_CDK_CDK2_CDK2_ST	Q9NYF8	BCLAF1	P24941	CDK2	S300	R298Q	298	Missense	proximal	-2	no	17.632	18.301	EPSD	COSMIC;GDSC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	Q9NYF8	BCLAF1	P24941	CDK2	S300	A306S	306	Missense	distal	6	no	17.632	17.637	EPSD	COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	Q9NYF8	BCLAF1	P24941	CDK2	S300	P301T	301	Missense	proximal	1	no	17.632	7.675	EPSD	COSMIC	8.148	Loss
CMGC_CDK_CDK2_CDK2_ST	Q9NYF8	BCLAF1	P24941	CDK2	S300	P301H	301	Missense	proximal	1	no	17.632	10.873	EPSD	COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	Q9NYF8	BCLAF1	P24941	CDK2	S385	G390R	390	Missense	distal	5	no	8.344	8.323	EPSD	COSMIC;GDSC;CCLE	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	Q9NYF8	BCLAF1	P24941	CDK2	S385	E379K	379	Missense	distal	-6	no	8.344	8.341	EPSD	COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	Q9NYF8	BCLAF1	P24941	CDK2	S385	D386G	386	Missense	proximal	1	no	8.344	9.275	EPSD	COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	Q9NYF8	BCLAF1	P24941	CDK2	S389	G390R	390	Missense	proximal	1	no	9.361	6.875	EPSD	COSMIC;GDSC;CCLE	8.148	Loss
CMGC_CDK_CDK2_CDK2_ST	Q9NYF8	BCLAF1	P24941	CDK2	S389	D386G	386	Missense	distal	-3	no	9.361	9.400	EPSD	COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	Q9NYF8	BCLAF1	P24941	CDK2	T402	T405K	405	Missense	distal	3	no	8.139	10.961	EPSD	COSMIC	8.148	Gain
CMGC_CDK_CDK2_CDK2_ST	Q9NYF8	BCLAF1	P24941	CDK2	S443	L444P	444	Missense	proximal	1	no	4.161	13.982	EPSD	COSMIC	8.148	Gain
CMGC_CDK_CDK2_CDK2_ST	Q9NYF8	BCLAF1	P24941	CDK2	T494	P497S	497	Missense	distal	3	no	8.177	8.211	EPSD	COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	Q9NYF8	BCLAF1	P24941	CDK2	T494	Q495E	495	Missense	proximal	1	no	8.177	6.923	EPSD	COSMIC	8.148	Loss
CMGC_CDK_CDK2_CDK2_ST	Q9NYF8	BCLAF1	P24941	CDK2	T494	R487K	487	Missense	distal	-7	no	8.177	7.787	EPSD	COSMIC	8.148	Loss
CMGC_CDK_CDK2_CDK2_ST	Q9NYF8	BCLAF1	P24941	CDK2	T494	E498K	498	Missense	distal	4	no	8.177	8.562	EPSD	COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	Q9NYF8	BCLAF1	P24941	CDK2	S496	P497S	497	Missense	proximal	1	no	13.721	2.455	EPSD	COSMIC	8.148	Loss
CMGC_CDK_CDK2_CDK2_ST	Q9NYF8	BCLAF1	P24941	CDK2	S496	Q495E	495	Missense	proximal	-1	no	13.721	14.813	EPSD	COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	Q9NYF8	BCLAF1	P24941	CDK2	S496	E498K	498	Missense	proximal	2	no	13.721	13.483	EPSD	COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	Q9NYF8	BCLAF1	P24941	CDK2	S512	P513S	513	Missense	proximal	1	no	14.296	3.030	EPSD	COSMIC	8.148	Loss
CMGC_CDK_CDK2_CDK2_ST	Q9NYF8	BCLAF1	P24941	CDK2	S512	N518D	518	Missense	distal	6	no	14.296	14.277	EPSD	COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	Q9NYF8	BCLAF1	P24941	CDK2	S512	N518H	518	Missense	distal	6	no	14.296	14.287	EPSD	COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	Q9NYF8	BCLAF1	P24941	CDK2	S512	F509L	509	Missense	distal	-3	no	14.296	14.038	EPSD	COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	Q9NYF8	BCLAF1	P24941	CDK2	S512	L519M	519	Missense	distal	7	no	14.296	14.810	EPSD	COSMIC;GDSC;CCLE	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	Q9NYF8	BCLAF1	P24941	CDK2	S531	R534S	534	Missense	distal	3	no	13.753	12.068	EPSD	COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	Q9NYF8	BCLAF1	P24941	CDK2	S531	M537I	537	Missense	distal	6	no	13.753	13.772	EPSD	COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	Q9NYF8	BCLAF1	P24941	CDK2	S531	E529K	529	Missense	proximal	-2	no	13.753	14.354	EPSD	COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	Q9NYF8	BCLAF1	P24941	CDK2	S542	S540C	540	Missense	proximal	-2	no	8.937	8.526	EPSD	COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	Q9NYF8	BCLAF1	P24941	CDK2	S542	M537I	537	Missense	distal	-5	no	8.937	8.869	EPSD	COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	Q9NYF8	BCLAF1	P24941	CDK2	S542	K548I	548	Missense	distal	6	no	8.937	8.928	EPSD	COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	Q9NYF8	BCLAF1	P24941	CDK2	S542	P545S	545	Missense	distal	3	no	8.937	8.971	EPSD	COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	Q9NYF8	BCLAF1	P24941	CDK2	S648	R645W	645	Missense	distal	-3	no	14.636	14.717	EPSD	COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	Q9NYF8	BCLAF1	P24941	CDK2	S648	R645L	645	Missense	distal	-3	no	14.636	14.376	EPSD	COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	Q9NYF8	BCLAF1	P24941	CDK2	S648	R654I	654	Missense	distal	6	no	14.636	14.652	EPSD	COSMIC;GDSC;CCLE	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	Q9NYF8	BCLAF1	P24941	CDK2	S658	H665D	665	Missense	distal	7	no	13.774	14.329	EPSD	COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	Q9NYF8	BCLAF1	P24941	CDK2	S658	D656V	656	Missense	proximal	-2	no	13.774	13.259	EPSD	COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	Q9NYF8	BCLAF1	P24941	CDK2	S658	L662M	662	Missense	distal	4	no	13.774	13.241	EPSD	COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	Q9NYF8	BCLAF1	P24941	CDK2	S658	D656G	656	Missense	proximal	-2	no	13.774	13.166	EPSD	COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	Q9NYF8	BCLAF1	P24941	CDK2	S658	R654I	654	Missense	distal	-4	no	13.774	13.866	EPSD	COSMIC;GDSC;CCLE	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	Q9NYF8	BCLAF1	P24941	CDK2	S660	H665D	665	Missense	distal	5	no	8.144	8.240	EPSD	COSMIC	8.148	Gain
CMGC_CDK_CDK2_CDK2_ST	Q9NYF8	BCLAF1	P24941	CDK2	S660	L662M	662	Missense	proximal	2	no	8.144	8.462	EPSD	COSMIC	8.148	Gain
CMGC_CDK_CDK2_CDK2_ST	Q9NYF8	BCLAF1	P24941	CDK2	S718	S718R	718	Missense	central	0	yes	8.581	0.000	EPSD	COSMIC	8.148	Loss
CMGC_CDK_CDK2_CDK2_ST	Q9NYF8	BCLAF1	P24941	CDK2	S718	S711F	711	Missense	distal	-7	no	8.581	9.132	EPSD	COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	Q9NYF8	BCLAF1	P24941	CDK2	S718	R715M	715	Missense	distal	-3	no	8.581	8.760	EPSD	COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	Q9NYF8	BCLAF1	P24941	CDK2	S718	G719E	719	Missense	proximal	1	no	8.581	6.727	EPSD	COSMIC	8.148	Loss
CMGC_CDK_CDK2_CDK2_ST	Q9NYF8	BCLAF1	P24941	CDK2	S718	S711T	711	Missense	distal	-7	no	8.581	8.758	EPSD	COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	Q9NYF8	BCLAF1	P24941	CDK2	T726	G719E	719	Missense	distal	-7	no	10.351	10.117	EPSD	COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	Q9NYF8	BCLAF1	P24941	CDK2	S757	S751Y	751	Missense	distal	-6	no	14.470	14.471	EPSD	COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	Q9NYF8	BCLAF1	P24941	CDK2	S757	S751C	751	Missense	distal	-6	no	14.470	14.476	EPSD	COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	Q9NYF8	BCLAF1	P24941	CDK2	S757	P758T	758	Missense	proximal	1	no	14.470	4.513	EPSD	COSMIC	8.148	Loss
CMGC_CDK_CDK2_CDK2_ST	Q9NYF8	BCLAF1	P24941	CDK2	S757	R750L	750	Missense	distal	-7	no	14.470	14.132	EPSD	COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	Q9NYF8	BCLAF1	P24941	CDK2	S757	A756T	756	Missense	proximal	-1	no	14.470	14.477	EPSD	COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	Q9NYF8	BCLAF1	P24941	CDK2	S757	R764Q	764	Missense	distal	7	no	14.470	13.826	EPSD	COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	Q9NYF8	BCLAF1	P24941	CDK2	S757	P761H	761	Missense	distal	4	no	14.470	14.232	EPSD	COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	Q9NYF8	BCLAF1	P24941	CDK2	S757	S753C	753	Missense	distal	-4	no	14.470	13.364	EPSD	COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	Q9NYF8	BCLAF1	P24941	CDK2	S760	P758T	758	Missense	proximal	-2	no	13.962	13.928	EPSD	COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	Q9NYF8	BCLAF1	P24941	CDK2	S760	A756T	756	Missense	distal	-4	no	13.962	14.187	EPSD	COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	Q9NYF8	BCLAF1	P24941	CDK2	S760	R764Q	764	Missense	distal	4	no	13.962	14.143	EPSD	COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	Q9NYF8	BCLAF1	P24941	CDK2	S760	P761H	761	Missense	proximal	1	no	13.962	7.203	EPSD	COSMIC	8.148	Loss
CMGC_CDK_CDK2_CDK2_ST	Q9NYF8	BCLAF1	P24941	CDK2	S760	S753C	753	Missense	distal	-7	no	13.962	14.413	EPSD	COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	Q9NYF8	BCLAF1	P24941	CDK2	T840	K842Q	842	Missense	proximal	2	no	16.936	17.136	PhosphoSitePlus	COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	Q9NYF8	BCLAF1	P24941	CDK2	T840	D836H	836	Missense	distal	-4	no	16.936	15.805	PhosphoSitePlus	COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	Q9NYF8	BCLAF1	P24941	CDK2	S881	T888N	888	Missense	distal	7	no	8.068	8.279	EPSD	COSMIC	8.148	Gain
CMGC_CDK_CDK2_CDK2_ST	Q9NYF8	BCLAF1	P24941	CDK2	S883	S881C	881	Missense	proximal	-2	no	9.117	8.706	EPSD	COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	Q9NYF8	BCLAF1	P24941	CDK2	S883	F876L	876	Missense	distal	-7	no	9.117	8.751	EPSD	COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	Q9NYF8	BCLAF1	P24941	CDK2	S883	S881N	881	Missense	proximal	-2	no	9.117	8.425	EPSD	COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	Q9NYF8	BCLAF1	P24941	CDK2	S883	S883N	883	Missense	central	0	yes	9.117	0.000	EPSD	COSMIC	8.148	Loss
CMGC_CDK_CDK2_CDK2_ST	Q9NYF8	BCLAF1	P24941	CDK2	S883	T888N	888	Missense	distal	5	no	9.117	9.245	EPSD	COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	Q9NYF8	BCLAF1	P24941	CDK2	S883	G882D	882	Missense	proximal	-1	no	9.117	8.824	EPSD	COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	Q9NYF8	BCLAF1	P24941	CDK2	S883	F878L	878	Missense	distal	-5	no	9.117	9.056	EPSD	COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	Q9NYF8	BCLAF1	P24941	CDK2	S883	G882C	882	Missense	proximal	-1	no	9.117	7.941	EPSD	COSMIC	8.148	Loss
CMGC_CDK_CDK2_CDK2_ST	Q9NYF8	BCLAF1	P24941	CDK2	S884	S881C	881	Missense	distal	-3	no	11.824	11.832	EPSD	COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	Q9NYF8	BCLAF1	P24941	CDK2	S884	S881N	881	Missense	distal	-3	no	11.824	11.750	EPSD	COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	Q9NYF8	BCLAF1	P24941	CDK2	S884	S883N	883	Missense	proximal	-1	no	11.824	12.222	EPSD	COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	Q9NYF8	BCLAF1	P24941	CDK2	S884	T888N	888	Missense	distal	4	no	11.824	11.521	EPSD	COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	Q9NYF8	BCLAF1	P24941	CDK2	S884	G882D	882	Missense	proximal	-2	no	11.824	12.432	EPSD	COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	Q9NYF8	BCLAF1	P24941	CDK2	S884	F878L	878	Missense	distal	-6	no	11.824	11.820	EPSD	COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	Q9NYF8	BCLAF1	P24941	CDK2	S884	G882C	882	Missense	proximal	-2	no	11.824	11.505	EPSD	COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	Q9NYF8	BCLAF1	P24941	CDK2	S884	K891Q	891	Missense	distal	7	no	11.824	11.956	EPSD	COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	Q9NYF8	BCLAF1	P24941	CDK2	T888	S881C	881	Missense	distal	-7	no	11.104	11.554	EPSD	COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	Q9NYF8	BCLAF1	P24941	CDK2	T888	S881N	881	Missense	distal	-7	no	11.104	11.202	EPSD	COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	Q9NYF8	BCLAF1	P24941	CDK2	T888	S883N	883	Missense	distal	-5	no	11.104	11.167	EPSD	COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	Q9NYF8	BCLAF1	P24941	CDK2	T888	T888N	888	Missense	central	0	yes	11.104	0.000	EPSD	COSMIC	8.148	Loss
CMGC_CDK_CDK2_CDK2_ST	Q9NYF8	BCLAF1	P24941	CDK2	T888	G882D	882	Missense	distal	-6	no	11.104	11.100	EPSD	COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	Q9NYF8	BCLAF1	P24941	CDK2	T888	D895E	895	Missense	distal	7	no	11.104	10.461	EPSD	COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	Q9NYF8	BCLAF1	P24941	CDK2	T888	G882C	882	Missense	distal	-6	no	11.104	11.107	EPSD	COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	Q9NYF8	BCLAF1	P24941	CDK2	T888	K891Q	891	Missense	distal	3	no	11.104	8.371	EPSD	COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	Q9UM11	FZR1	P24941	CDK2	T32	R29Q	29	Missense	distal	-3	no	14.341	14.211	EPSD	COSMIC;GDSC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	Q9UM11	FZR1	P24941	CDK2	S36	R29Q	29	Missense	distal	-7	no	13.707	13.320	EPSD	COSMIC;GDSC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	Q9UM11	FZR1	P24941	CDK2	S70	S70F	70	Missense	central	0	yes	13.290	0.000	EPSD	COSMIC;GDSC;CCLE	8.148	Loss
CMGC_CDK_CDK2_CDK2_ST	Q9UM11	FZR1	P24941	CDK2	S70	P71A	71	Missense	proximal	1	no	13.290	-1.113	EPSD	COSMIC	8.148	Loss
CMGC_CDK_CDK2_CDK2_ST	Q9UM11	FZR1	P24941	CDK2	S72	S70F	70	Missense	proximal	-2	no	8.385	7.923	EPSD	COSMIC;GDSC;CCLE	8.148	Loss
CMGC_CDK_CDK2_CDK2_ST	Q9UM11	FZR1	P24941	CDK2	S72	P71A	71	Missense	proximal	-1	no	8.385	8.114	EPSD	COSMIC	8.148	Loss
CMGC_CDK_CDK2_CDK2_ST	Q9UM11	FZR1	P24941	CDK2	T121	K124N	124	Missense	distal	3	no	18.297	15.027	EPSD;PhosphoSitePlus	COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	Q9UM11	FZR1	P24941	CDK2	S146	P152L	152	Missense	distal	6	no	13.003	13.005	EPSD	COSMIC;GDSC;CCLE	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	Q9UM11	FZR1	P24941	CDK2	S146	P147S	147	Missense	proximal	1	no	13.003	1.737	EPSD	COSMIC	8.148	Loss
CMGC_CDK_CDK2_CDK2_ST	Q9UM11	FZR1	P24941	CDK2	S151	N155S	155	Missense	distal	4	no	12.991	13.024	EPSD;PhosphoSitePlus	COSMIC;GDSC;CCLE	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	Q9UM11	FZR1	P24941	CDK2	S151	P152L	152	Missense	proximal	1	no	12.991	3.170	EPSD;PhosphoSitePlus	COSMIC;GDSC;CCLE	8.148	Loss
CMGC_CDK_CDK2_CDK2_ST	Q9UM11	FZR1	P24941	CDK2	S151	P147S	147	Missense	distal	-4	no	12.991	13.345	EPSD;PhosphoSitePlus	COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	Q9UM11	FZR1	P24941	CDK2	T300	T300P	300	Missense	central	0	yes	14.296	0.000	EPSD	COSMIC	8.148	Loss
CMGC_CDK_CDK2_CDK2_ST	Q9UM11	FZR1	P24941	CDK2	S346	S343A	343	Missense	distal	-3	no	11.717	11.563	EPSD	COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	Q9UM11	FZR1	P24941	CDK2	S346	E353D	353	Missense	distal	7	no	11.717	12.359	EPSD	COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	Q9UM11	FZR1	P24941	CDK2	S346	V348M	348	Missense	proximal	2	no	11.717	11.805	EPSD	COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	Q9UM11	FZR1	P24941	CDK2	S346	Q350L	350	Missense	distal	4	no	11.717	11.768	EPSD	COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	Q9UM11	FZR1	P24941	CDK2	S346	H342D	342	Missense	distal	-4	no	11.717	12.848	EPSD	COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	P49459	UBE2A	P24941	CDK2	S120	Q125K	125	Missense	distal	5	no	17.215	17.201	PhosphoSitePlus	COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	P49459	UBE2A	P24941	CDK2	S120	P116L	116	Missense	distal	-4	no	17.215	17.157	PhosphoSitePlus	COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	Q08050	FOXM1	P24941	CDK2	S4	R6S	6	Missense	proximal	2	no	12.345	12.252	EPSD	COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	Q08050	FOXM1	P24941	CDK2	S35	E31K	31	Missense	distal	-4	no	14.560	14.249	EPSD	COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	Q08050	FOXM1	P24941	CDK2	S331	F324L	324	Missense	distal	-7	no	15.331	14.965	EPSD	COSMIC;GDSC;CCLE	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	Q08050	FOXM1	P24941	CDK2	S331	P332A	332	Missense	proximal	1	no	15.331	0.927	EPSD	COSMIC	8.148	Loss
CMGC_CDK_CDK2_CDK2_ST	Q08050	FOXM1	P24941	CDK2	S340	R344Q	344	Missense	distal	4	no	11.158	11.339	EPSD	COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	Q08050	FOXM1	P24941	CDK2	S451	E448K	448	Missense	distal	-3	no	14.759	14.544	EPSD	COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	Q08050	FOXM1	P24941	CDK2	S451	P455L	455	Missense	distal	4	no	14.759	14.871	EPSD	COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	Q08050	FOXM1	P24941	CDK2	S451	P455S	455	Missense	distal	4	no	14.759	14.772	EPSD	COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	Q08050	FOXM1	P24941	CDK2	S451	F450L	450	Missense	proximal	-1	no	14.759	13.794	EPSD	COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	Q08050	FOXM1	P24941	CDK2	S481	E486Q	486	Missense	distal	5	no	14.225	14.105	EPSD	COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	Q08050	FOXM1	P24941	CDK2	S481	R475T	475	Missense	distal	-6	no	14.225	14.222	EPSD	COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	Q08050	FOXM1	P24941	CDK2	S481	E480K	480	Missense	proximal	-1	no	14.225	13.339	EPSD	COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	Q08050	FOXM1	P24941	CDK2	S489	E486Q	486	Missense	distal	-3	no	12.121	12.004	EPSD	COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	Q08050	FOXM1	P24941	CDK2	S489	P492L	492	Missense	distal	3	no	12.121	11.737	EPSD	COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	Q08050	FOXM1	P24941	CDK2	S508	S505L	505	Missense	distal	-3	no	13.254	13.088	EPSD	COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	Q08050	FOXM1	P24941	CDK2	S508	T510N	510	Missense	proximal	2	no	13.254	13.361	EPSD	COSMIC;CCLE	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	Q08050	FOXM1	P24941	CDK2	T510	S505L	505	Missense	distal	-5	no	17.092	17.148	EPSD	COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	Q08050	FOXM1	P24941	CDK2	T510	T510N	510	Missense	central	0	yes	17.092	0.000	EPSD	COSMIC;CCLE	8.148	Loss
CMGC_CDK_CDK2_CDK2_ST	Q08050	FOXM1	P24941	CDK2	S518	R521M	521	Missense	distal	3	no	9.017	7.059	EPSD	COSMIC	8.148	Loss
CMGC_CDK_CDK2_CDK2_ST	Q08050	FOXM1	P24941	CDK2	S518	T524S	524	Missense	distal	6	no	9.017	9.011	EPSD	COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	Q08050	FOXM1	P24941	CDK2	S518	S518I	518	Missense	central	0	yes	9.017	0.000	EPSD	COSMIC	8.148	Loss
CMGC_CDK_CDK2_CDK2_ST	Q08050	FOXM1	P24941	CDK2	S518	R525W	525	Missense	distal	7	no	9.017	9.417	EPSD	COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	Q08050	FOXM1	P24941	CDK2	S522	R521M	521	Missense	proximal	-1	no	15.752	16.231	EPSD	COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	Q08050	FOXM1	P24941	CDK2	S522	T524S	524	Missense	proximal	2	no	15.752	15.996	EPSD	COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	Q08050	FOXM1	P24941	CDK2	S522	S518I	518	Missense	distal	-4	no	15.752	15.246	EPSD	COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	Q08050	FOXM1	P24941	CDK2	S522	V527A	527	Missense	distal	5	no	15.752	15.795	EPSD	COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	Q08050	FOXM1	P24941	CDK2	S522	R525W	525	Missense	distal	3	no	15.752	13.112	EPSD	COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	Q08050	FOXM1	P24941	CDK2	S522	C526S	526	Missense	distal	4	no	15.752	16.512	EPSD	COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	Q08050	FOXM1	P24941	CDK2	S591	S591F	591	Missense	central	0	yes	8.281	0.000	EPSD	COSMIC	8.148	Loss
CMGC_CDK_CDK2_CDK2_ST	Q08050	FOXM1	P24941	CDK2	S591	S589N	589	Missense	proximal	-2	no	8.281	7.589	EPSD	COSMIC	8.148	Loss
CMGC_CDK_CDK2_CDK2_ST	Q08050	FOXM1	P24941	CDK2	S591	S586T	586	Missense	distal	-5	no	8.281	8.324	EPSD	COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	Q08050	FOXM1	P24941	CDK2	S591	P584S	584	Missense	distal	-7	no	8.281	8.101	EPSD	COSMIC	8.148	Loss
CMGC_CDK_CDK2_CDK2_ST	Q08050	FOXM1	P24941	CDK2	T600	T605M	605	Missense	distal	5	no	13.533	13.866	EPSD	COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	Q08050	FOXM1	P24941	CDK2	T611	S615Y	615	Missense	distal	4	no	15.316	15.501	EPSD	COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	Q08050	FOXM1	P24941	CDK2	T611	S610T	610	Missense	proximal	-1	no	15.316	15.523	EPSD	COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	Q08050	FOXM1	P24941	CDK2	T611	T605M	605	Missense	distal	-6	no	15.316	15.323	EPSD	COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	Q08050	FOXM1	P24941	CDK2	T620	S615Y	615	Missense	distal	-5	no	12.360	12.428	EPSD	COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	Q08050	FOXM1	P24941	CDK2	T620	P621L	621	Missense	proximal	1	no	12.360	2.539	EPSD	COSMIC	8.148	Loss
CMGC_CDK_CDK2_CDK2_ST	Q08050	FOXM1	P24941	CDK2	T620	W624C	624	Missense	distal	4	no	12.360	12.093	EPSD	COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	Q08050	FOXM1	P24941	CDK2	T627	V632G	632	Missense	distal	5	no	13.034	13.193	EPSD	COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	Q08050	FOXM1	P24941	CDK2	T627	G633E	633	Missense	distal	6	no	13.034	13.042	EPSD	COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	Q08050	FOXM1	P24941	CDK2	T627	W624C	624	Missense	distal	-3	no	13.034	12.867	EPSD	COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	Q08050	FOXM1	P24941	CDK2	S638	D636H	636	Missense	proximal	-2	no	15.660	14.785	EPSD	COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	Q08050	FOXM1	P24941	CDK2	S638	S643P	643	Missense	distal	5	no	15.660	15.761	EPSD	COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	Q08050	FOXM1	P24941	CDK2	S638	V632G	632	Missense	distal	-6	no	15.660	15.661	EPSD	COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	Q08050	FOXM1	P24941	CDK2	S638	G633E	633	Missense	distal	-5	no	15.660	15.618	EPSD	COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	Q08050	FOXM1	P24941	CDK2	T662	P663H	663	Missense	proximal	1	no	14.157	7.398	EPSD	COSMIC	8.148	Loss
CMGC_CDK_CDK2_CDK2_ST	Q08050	FOXM1	P24941	CDK2	T662	L659P	659	Missense	distal	-3	no	14.157	14.228	EPSD	COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	Q08050	FOXM1	P24941	CDK2	T662	S666N	666	Missense	distal	4	no	14.157	14.124	EPSD	COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	Q08050	FOXM1	P24941	CDK2	T662	P669L	669	Missense	distal	7	no	14.157	14.187	EPSD	COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	Q08050	FOXM1	P24941	CDK2	S672	P673S	673	Missense	proximal	1	no	16.081	4.815	EPSD	COSMIC	8.148	Loss
CMGC_CDK_CDK2_CDK2_ST	Q08050	FOXM1	P24941	CDK2	S672	R675K	675	Missense	distal	3	no	16.081	17.070	EPSD	COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	Q08050	FOXM1	P24941	CDK2	S672	P669L	669	Missense	distal	-3	no	16.081	16.010	EPSD	COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	Q08050	FOXM1	P24941	CDK2	S672	L670P	670	Missense	proximal	-2	no	16.081	16.305	EPSD	COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	Q08050	FOXM1	P24941	CDK2	S693	S695L	695	Missense	proximal	2	no	9.233	9.060	EPSD	COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	Q08050	FOXM1	P24941	CDK2	S693	P688S	688	Missense	distal	-5	no	9.233	9.189	EPSD	COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	Q08050	FOXM1	P24941	CDK2	S693	V699I	699	Missense	distal	6	no	9.233	9.235	EPSD	COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	Q08050	FOXM1	P24941	CDK2	S693	S686F	686	Missense	distal	-7	no	9.233	9.784	EPSD	COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	Q08050	FOXM1	P24941	CDK2	S704	V699I	699	Missense	distal	-5	no	17.281	17.290	EPSD	COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	Q08050	FOXM1	P24941	CDK2	S704	P707L	707	Missense	distal	3	no	17.281	16.898	EPSD	COSMIC;GDSC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	Q08050	FOXM1	P24941	CDK2	S730	K733N	733	Missense	distal	3	no	9.092	5.822	EPSD	COSMIC	8.148	Loss
CMGC_CDK_CDK2_CDK2_ST	Q08050	FOXM1	P24941	CDK2	S730	L724M	724	Missense	distal	-6	no	9.092	9.099	EPSD	COSMIC;CCLE	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	Q08050	FOXM1	P24941	CDK2	S730	D725G	725	Missense	distal	-5	no	9.092	9.114	EPSD	COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	Q00536	CDK16	P24941	CDK2	S95	R102C	102	Missense	distal	7	no	14.949	15.101	EPSD	COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	Q00536	CDK16	P24941	CDK2	S95	P96T	96	Missense	proximal	1	no	14.949	4.992	EPSD	COSMIC	8.148	Loss
CMGC_CDK_CDK2_CDK2_ST	Q00536	CDK16	P24941	CDK2	S95	R100C	100	Missense	distal	5	no	14.949	15.077	EPSD	COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	Q00536	CDK16	P24941	CDK2	S95	R102H	102	Missense	distal	7	no	14.949	14.591	EPSD	COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	Q00536	CDK16	P24941	CDK2	S138	P139L	139	Missense	proximal	1	no	13.639	3.818	PhosphoSitePlus	COSMIC	8.148	Loss
CMGC_CDK_CDK2_CDK2_ST	Q00536	CDK16	P24941	CDK2	T380	R376H	376	Missense	distal	-4	no	14.442	14.081	EPSD	COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	Q00536	CDK16	P24941	CDK2	T380	P381S	381	Missense	proximal	1	no	14.442	3.176	EPSD	COSMIC	8.148	Loss
CMGC_CDK_CDK2_CDK2_ST	Q00536	CDK16	P24941	CDK2	T380	I374V	374	Missense	distal	-6	no	14.442	14.441	EPSD	COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	Q00536	CDK16	P24941	CDK2	T380	T385M	385	Missense	distal	5	no	14.442	14.775	EPSD	COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	Q00536	CDK16	P24941	CDK2	T380	P387S	387	Missense	distal	7	no	14.442	14.290	EPSD	COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	Q9Y2W1	THRAP3	P24941	CDK2	S49	R50H	50	Missense	proximal	1	no	6.955	9.995	EPSD	COSMIC;GDSC;CCLE	8.148	Gain
CMGC_CDK_CDK2_CDK2_ST	Q9Y2W1	THRAP3	P24941	CDK2	S119	G123S	123	Missense	distal	4	no	17.576	17.709	EPSD	COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	Q9Y2W1	THRAP3	P24941	CDK2	S119	N113K	113	Missense	distal	-6	no	17.576	17.577	EPSD	COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	Q9Y2W1	THRAP3	P24941	CDK2	S119	Y114H	114	Missense	distal	-5	no	17.576	17.599	EPSD	COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	Q9Y2W1	THRAP3	P24941	CDK2	S134	S129P	129	Missense	distal	-5	no	12.306	12.351	EPSD	COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	Q9Y2W1	THRAP3	P24941	CDK2	S134	P137L	137	Missense	distal	3	no	12.306	11.923	EPSD	COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	Q9Y2W1	THRAP3	P24941	CDK2	S136	S129P	129	Missense	distal	-7	no	11.087	11.267	EPSD	COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	Q9Y2W1	THRAP3	P24941	CDK2	S136	P137L	137	Missense	proximal	1	no	11.087	1.267	EPSD	COSMIC	8.148	Loss
CMGC_CDK_CDK2_CDK2_ST	Q9Y2W1	THRAP3	P24941	CDK2	S243	R247Q	247	Missense	distal	4	no	15.395	15.577	EPSD	COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	Q9Y2W1	THRAP3	P24941	CDK2	S248	R247Q	247	Missense	proximal	-1	no	10.981	10.103	EPSD	COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	Q9Y2W1	THRAP3	P24941	CDK2	S264	R266H	266	Missense	proximal	2	no	10.417	10.335	EPSD	COSMIC;GDSC;CCLE	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	Q9Y2W1	THRAP3	P24941	CDK2	S264	R262Q	262	Missense	proximal	-2	no	10.417	11.085	EPSD	COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	Q9Y2W1	THRAP3	P24941	CDK2	S268	R266H	266	Missense	proximal	-2	no	12.706	12.932	EPSD	COSMIC;GDSC;CCLE	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	Q9Y2W1	THRAP3	P24941	CDK2	S268	R262Q	262	Missense	distal	-6	no	12.706	12.707	EPSD	COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	Q9Y2W1	THRAP3	P24941	CDK2	S310	S308C	308	Missense	proximal	-2	no	16.360	15.949	EPSD	COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	Q9Y2W1	THRAP3	P24941	CDK2	S310	H304Y	304	Missense	distal	-6	no	16.360	16.356	EPSD	COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	Q9Y2W1	THRAP3	P24941	CDK2	S315	S308C	308	Missense	distal	-7	no	11.071	11.521	EPSD	COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	Q9Y2W1	THRAP3	P24941	CDK2	S408	P409S	409	Missense	proximal	1	no	14.974	3.708	EPSD	COSMIC	8.148	Loss
CMGC_CDK_CDK2_CDK2_ST	Q9Y2W1	THRAP3	P24941	CDK2	S544	K551R	551	Missense	distal	7	no	8.068	8.844	EPSD	COSMIC	8.148	Gain
CMGC_CDK_CDK2_CDK2_ST	Q9Y2W1	THRAP3	P24941	CDK2	S622	R621H	621	Missense	proximal	-1	no	16.415	15.963	EPSD	COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	Q9Y2W1	THRAP3	P24941	CDK2	S622	P623S	623	Missense	proximal	1	no	16.415	5.149	EPSD	COSMIC	8.148	Loss
CMGC_CDK_CDK2_CDK2_ST	Q9Y2W1	THRAP3	P24941	CDK2	S672	I679T	679	Missense	distal	7	no	11.734	11.373	EPSD	COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	Q9Y2W1	THRAP3	P24941	CDK2	S682	I679T	679	Missense	distal	-3	no	13.357	13.298	EPSD	COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	Q9Y2W1	THRAP3	P24941	CDK2	S698	G703D	703	Missense	distal	5	no	12.761	12.808	EPSD	COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	Q9Y2W1	THRAP3	P24941	CDK2	S787	Y790H	790	Missense	distal	3	no	6.657	8.425	EPSD	COSMIC	8.148	Gain
CMGC_CDK_CDK2_CDK2_ST	Q9Y2W1	THRAP3	P24941	CDK2	T874	K879M	879	Missense	distal	5	no	13.970	14.332	PhosphoSitePlus	COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	Q9Y2W1	THRAP3	P24941	CDK2	S919	A923P	923	Missense	distal	4	no	13.602	13.562	EPSD	COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	Q9Y2W1	THRAP3	P24941	CDK2	S939	E942Q	942	Missense	distal	3	no	9.791	9.144	EPSD	COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	Q9Y2W1	THRAP3	P24941	CDK2	T941	E942Q	942	Missense	proximal	1	no	10.445	11.699	EPSD	COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	Q9H425	C1orf198	P24941	CDK2	S17	A10T	10	Missense	distal	-7	no	9.478	9.310	EPSD	COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	Q9H425	C1orf198	P24941	CDK2	S37	P38H	38	Missense	proximal	1	no	13.372	6.614	PhosphoSitePlus	COSMIC	8.148	Loss
CMGC_CDK_CDK2_CDK2_ST	Q9H425	C1orf198	P24941	CDK2	S37	A40T	40	Missense	distal	3	no	13.372	13.770	PhosphoSitePlus	COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	Q9H425	C1orf198	P24941	CDK2	S167	S168P	168	Missense	proximal	1	no	2.063	13.329	EPSD	COSMIC	8.148	Gain
CMGC_CDK_CDK2_CDK2_ST	Q9H425	C1orf198	P24941	CDK2	T211	S217F	217	Missense	distal	6	no	14.429	14.410	EPSD	COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	Q9H425	C1orf198	P24941	CDK2	T211	A205T	205	Missense	distal	-6	no	14.429	14.430	EPSD	COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	Q9H425	C1orf198	P24941	CDK2	T211	P212S	212	Missense	proximal	1	no	14.429	3.163	EPSD	COSMIC	8.148	Loss
CMGC_CDK_CDK2_CDK2_ST	Q9H425	C1orf198	P24941	CDK2	S281	E284K	284	Missense	distal	3	no	6.344	8.429	EPSD	COSMIC	8.148	Gain
CMGC_CDK_CDK2_CDK2_ST	Q9H425	C1orf198	P24941	CDK2	S289	D295H	295	Missense	distal	6	no	12.988	12.998	EPSD	COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	Q9H425	C1orf198	P24941	CDK2	S289	E284K	284	Missense	distal	-5	no	12.988	12.954	EPSD	COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	P15927	RPA2	P24941	CDK2	S29	Q34K	34	Missense	distal	5	no	13.746	13.732	PhosphoSitePlus;EPSD	COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	P15927	RPA2	P24941	CDK2	S33	Q34K	34	Missense	proximal	1	no	9.960	0.222	EPSD;PhosphoSitePlus	COSMIC	8.148	Loss
CMGC_CDK_CDK2_CDK2_ST	P15927	RPA2	P24941	CDK2	S33	K37N	37	Missense	distal	4	no	9.960	9.539	EPSD;PhosphoSitePlus	COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	P49736	MCM2	P24941	CDK2	S27	R33W	33	Missense	distal	6	no	15.798	15.791	EPSD;PhosphoSitePlus	COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	P49736	MCM2	P24941	CDK2	S27	R34H	34	Missense	distal	7	no	15.798	15.440	EPSD;PhosphoSitePlus	COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	P49736	MCM2	P24941	CDK2	S41	T39I	39	Missense	proximal	-2	no	15.832	15.711	PhosphoSitePlus;EPSD	COSMIC;GDSC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	P49736	MCM2	P24941	CDK2	S41	R34H	34	Missense	distal	-7	no	15.832	15.612	PhosphoSitePlus;EPSD	COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	P49736	MCM2	P24941	CDK2	S53	F49C	49	Missense	distal	-4	no	8.480	8.336	EPSD;PhosphoSitePlus	COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	P49736	MCM2	P24941	CDK2	S53	E54V	54	Missense	proximal	1	no	8.480	0.733	EPSD;PhosphoSitePlus	COSMIC	8.148	Loss
CMGC_CDK_CDK2_CDK2_ST	P49736	MCM2	P24941	CDK2	S108	E104K	104	Missense	distal	-4	no	9.985	9.673	EPSD;PhosphoSitePlus	COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	P49736	MCM2	P24941	CDK2	S108	R115W	115	Missense	distal	7	no	9.985	10.384	EPSD;PhosphoSitePlus	COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	P49736	MCM2	P24941	CDK2	S108	S108R	108	Missense	central	0	yes	9.985	0.000	EPSD;PhosphoSitePlus	COSMIC	8.148	Loss
CMGC_CDK_CDK2_CDK2_ST	P49736	MCM2	P24941	CDK2	S108	A112T	112	Missense	distal	4	no	9.985	10.228	EPSD;PhosphoSitePlus	COSMIC;GDSC;CCLE	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	P49736	MCM2	P24941	CDK2	S139	R132P	132	Missense	distal	-7	no	8.904	8.560	EPSD;PhosphoSitePlus	COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	P49736	MCM2	P24941	CDK2	S139	R146C	146	Missense	distal	7	no	8.904	9.055	EPSD;PhosphoSitePlus	COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	P49736	MCM2	P24941	CDK2	S209	H206D	206	Missense	distal	-3	no	9.821	9.740	EPSD	COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	P49736	MCM2	P24941	CDK2	T805	V810I	810	Missense	distal	5	no	9.534	9.660	EPSD	COSMIC;GDSC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	P49736	MCM2	P24941	CDK2	T805	M811T	811	Missense	distal	6	no	9.534	9.560	EPSD	COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	P49736	MCM2	P24941	CDK2	S813	M814T	814	Missense	proximal	1	no	-8.136	8.719	EPSD	COSMIC	8.148	Gain
CMGC_CDK_CDK2_CDK2_ST	P55273	CDKN2D	P24941	CDK2	S66	T72I	72	Missense	distal	6	no	14.025	14.018	EPSD	COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	P55273	CDKN2D	P24941	CDK2	S76	H79Y	79	Missense	distal	3	no	15.359	13.592	PhosphoSitePlus	COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	P55273	CDKN2D	P24941	CDK2	S76	T72I	72	Missense	distal	-4	no	15.359	15.042	PhosphoSitePlus	COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	P55273	CDKN2D	P24941	CDK2	S76	A81T	81	Missense	distal	5	no	15.359	15.324	PhosphoSitePlus	COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	P55273	CDKN2D	P24941	CDK2	T141	P142L	142	Missense	proximal	1	no	15.112	5.291	EPSD	COSMIC	8.148	Loss
CMGC_CDK_CDK2_CDK2_ST	P55273	CDKN2D	P24941	CDK2	T141	A146V	146	Missense	distal	5	no	15.112	15.069	EPSD	COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	Q14191	WRN	P24941	CDK2	S179	H183R	183	Missense	distal	4	no	8.451	8.569	EPSD	COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	Q14191	WRN	P24941	CDK2	S426	D433N	433	Missense	distal	7	no	12.318	11.538	EPSD	COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	Q14191	WRN	P24941	CDK2	S453	E447K	447	Missense	distal	-6	no	14.048	14.046	EPSD	COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	Q14191	WRN	P24941	CDK2	S453	M446I	446	Missense	distal	-7	no	14.048	13.741	EPSD	COSMIC;GDSC;CCLE	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	Q14191	WRN	P24941	CDK2	S453	N459K	459	Missense	distal	6	no	14.048	14.053	EPSD	COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	Q14191	WRN	P24941	CDK2	S453	M448K	448	Missense	distal	-5	no	14.048	13.944	EPSD	COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	Q14191	WRN	P24941	CDK2	T490	S492F	492	Missense	proximal	2	no	9.946	10.131	EPSD	COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	Q14191	WRN	P24941	CDK2	T490	S484N	484	Missense	distal	-6	no	9.946	9.947	EPSD	COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	Q14191	WRN	P24941	CDK2	T629	I631T	631	Missense	proximal	2	no	8.331	8.177	EPSD	COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	Q14191	WRN	P24941	CDK2	S915	R909S	909	Missense	distal	-6	no	9.316	9.313	EPSD	COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	Q14191	WRN	P24941	CDK2	S1133	K1126R	1126	Missense	distal	-7	no	16.492	16.883	PhosphoSitePlus	COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	Q14191	WRN	P24941	CDK2	S1133	A1137G	1137	Missense	distal	4	no	16.492	16.332	PhosphoSitePlus	COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	Q14191	WRN	P24941	CDK2	S1133	S1128G	1128	Missense	distal	-5	no	16.492	16.616	PhosphoSitePlus	COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	Q7Z2Z1	TICRR	P24941	CDK2	S441	S441N	441	Missense	central	0	yes	13.855	0.000	EPSD	COSMIC	8.148	Loss
CMGC_CDK_CDK2_CDK2_ST	Q7Z2Z1	TICRR	P24941	CDK2	T486	T485S	485	Missense	proximal	-1	no	12.195	11.987	EPSD	COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	Q7Z2Z1	TICRR	P24941	CDK2	S489	T485S	485	Missense	distal	-4	no	19.263	19.451	EPSD	COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	Q7Z2Z1	TICRR	P24941	CDK2	T566	Q570H	570	Missense	distal	4	no	16.179	15.880	EPSD	COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	Q7Z2Z1	TICRR	P24941	CDK2	T566	K559N	559	Missense	distal	-7	no	16.179	16.144	EPSD	COSMIC;GDSC;CCLE	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	Q7Z2Z1	TICRR	P24941	CDK2	S820	L823P	823	Missense	distal	3	no	11.353	11.737	EPSD	COSMIC;GDSC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	Q7Z2Z1	TICRR	P24941	CDK2	S820	L822P	822	Missense	proximal	2	no	11.353	11.460	EPSD	COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	Q7Z2Z1	TICRR	P24941	CDK2	S838	E840A	840	Missense	proximal	2	no	13.163	13.091	EPSD	COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	Q7Z2Z1	TICRR	P24941	CDK2	S838	R832C	832	Missense	distal	-6	no	13.163	13.166	EPSD	COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	Q7Z2Z1	TICRR	P24941	CDK2	S923	L922F	922	Missense	proximal	-1	no	14.714	15.679	EPSD	COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	Q7Z2Z1	TICRR	P24941	CDK2	S923	L921F	921	Missense	proximal	-2	no	14.714	13.825	EPSD	COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	Q7Z2Z1	TICRR	P24941	CDK2	S936	V942A	942	Missense	distal	6	no	10.012	10.009	EPSD	COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	Q7Z2Z1	TICRR	P24941	CDK2	S1001	E1000K	1000	Missense	proximal	-1	no	16.333	15.448	PhosphoSitePlus;EPSD	COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	Q7Z2Z1	TICRR	P24941	CDK2	S1001	E999K	999	Missense	proximal	-2	no	16.333	16.934	PhosphoSitePlus;EPSD	COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	Q7Z2Z1	TICRR	P24941	CDK2	S1057	R1063Q	1063	Missense	distal	6	no	11.084	11.106	EPSD	COSMIC;GDSC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	Q7Z2Z1	TICRR	P24941	CDK2	S1057	N1056K	1056	Missense	proximal	-1	no	11.084	11.057	EPSD	COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	Q7Z2Z1	TICRR	P24941	CDK2	S1064	R1063Q	1063	Missense	proximal	-1	no	14.114	13.236	EPSD	COSMIC;GDSC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	Q7Z2Z1	TICRR	P24941	CDK2	S1064	F1070C	1070	Missense	distal	6	no	14.114	14.118	EPSD	COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	Q7Z2Z1	TICRR	P24941	CDK2	S1064	L1069F	1069	Missense	distal	5	no	14.114	14.291	EPSD	COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	Q7Z2Z1	TICRR	P24941	CDK2	S1064	L1068I	1068	Missense	distal	4	no	14.114	13.973	EPSD	COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	Q7Z2Z1	TICRR	P24941	CDK2	S1064	L1068F	1068	Missense	distal	4	no	14.114	13.819	EPSD	COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	Q7Z2Z1	TICRR	P24941	CDK2	S1078	M1073I	1073	Missense	distal	-5	no	14.068	14.000	EPSD	COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	Q7Z2Z1	TICRR	P24941	CDK2	S1078	I1077T	1077	Missense	proximal	-1	no	14.068	13.822	EPSD	COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	Q7Z2Z1	TICRR	P24941	CDK2	T1105	Q1104R	1104	Missense	proximal	-1	no	14.479	15.357	EPSD	COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	Q7Z2Z1	TICRR	P24941	CDK2	S1109	Q1104R	1104	Missense	distal	-5	no	10.138	10.185	EPSD	COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	Q7Z2Z1	TICRR	P24941	CDK2	T1120	T1127I	1127	Missense	distal	7	no	12.660	13.021	EPSD	COSMIC;GDSC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	Q7Z2Z1	TICRR	P24941	CDK2	T1120	R1122T	1122	Missense	proximal	2	no	12.660	12.324	EPSD	COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	Q7Z2Z1	TICRR	P24941	CDK2	T1127	Q1129H	1129	Missense	proximal	2	no	9.261	9.280	EPSD	COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	Q7Z2Z1	TICRR	P24941	CDK2	T1127	T1127I	1127	Missense	central	0	yes	9.261	0.000	EPSD	COSMIC;GDSC	8.148	Loss
CMGC_CDK_CDK2_CDK2_ST	Q7Z2Z1	TICRR	P24941	CDK2	T1127	R1122T	1122	Missense	distal	-5	no	9.261	9.213	EPSD	COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	Q7Z2Z1	TICRR	P24941	CDK2	T1130	Q1129H	1129	Missense	proximal	-1	no	15.757	16.184	EPSD	COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	Q7Z2Z1	TICRR	P24941	CDK2	T1130	T1127I	1127	Missense	distal	-3	no	15.757	15.816	EPSD	COSMIC;GDSC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	Q7Z2Z1	TICRR	P24941	CDK2	T1130	R1137S	1137	Missense	distal	7	no	15.757	15.115	EPSD	COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	Q7Z2Z1	TICRR	P24941	CDK2	T1134	Q1129H	1129	Missense	distal	-5	no	15.645	15.692	EPSD	COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	Q7Z2Z1	TICRR	P24941	CDK2	T1134	T1127I	1127	Missense	distal	-7	no	15.645	15.842	EPSD	COSMIC;GDSC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	Q7Z2Z1	TICRR	P24941	CDK2	T1134	R1137S	1137	Missense	distal	3	no	15.645	13.961	EPSD	COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	Q7Z2Z1	TICRR	P24941	CDK2	S1141	R1137S	1137	Missense	distal	-4	no	12.640	13.238	EPSD	COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	Q7Z2Z1	TICRR	P24941	CDK2	S1162	E1155D	1155	Missense	distal	-7	no	13.627	13.778	EPSD	COSMIC;GDSC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	Q7Z2Z1	TICRR	P24941	CDK2	S1162	G1164S	1164	Missense	proximal	2	no	13.627	13.576	EPSD	COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	Q7Z2Z1	TICRR	P24941	CDK2	S1167	D1170Y	1170	Missense	distal	3	no	10.581	11.649	EPSD	COSMIC;GDSC;CCLE	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	Q7Z2Z1	TICRR	P24941	CDK2	S1167	G1164S	1164	Missense	distal	-3	no	10.581	10.572	EPSD	COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	Q7Z2Z1	TICRR	P24941	CDK2	T1174	D1170Y	1170	Missense	distal	-4	no	15.977	15.916	EPSD	COSMIC;GDSC;CCLE	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	Q7Z2Z1	TICRR	P24941	CDK2	T1192	P1196A	1196	Missense	distal	4	no	11.791	11.830	EPSD	COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	Q7Z2Z1	TICRR	P24941	CDK2	T1195	P1196A	1196	Missense	proximal	1	no	13.626	-0.777	EPSD	COSMIC	8.148	Loss
CMGC_CDK_CDK2_CDK2_ST	Q7Z2Z1	TICRR	P24941	CDK2	S1219	P1223S	1223	Missense	distal	4	no	12.313	12.326	EPSD	COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	Q7Z2Z1	TICRR	P24941	CDK2	S1222	P1223S	1223	Missense	proximal	1	no	8.606	-2.660	EPSD	COSMIC	8.148	Loss
CMGC_CDK_CDK2_CDK2_ST	Q7Z2Z1	TICRR	P24941	CDK2	S1222	P1229L	1229	Missense	distal	7	no	8.606	8.636	EPSD	COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	Q7Z2Z1	TICRR	P24941	CDK2	S1222	P1228L	1228	Missense	distal	6	no	8.606	8.607	EPSD	COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	Q7Z2Z1	TICRR	P24941	CDK2	T1242	P1243H	1243	Missense	proximal	1	no	14.880	8.121	EPSD	COSMIC	8.148	Loss
CMGC_CDK_CDK2_CDK2_ST	Q7Z2Z1	TICRR	P24941	CDK2	T1250	A1256V	1256	Missense	distal	6	no	14.822	14.824	EPSD	COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	Q7Z2Z1	TICRR	P24941	CDK2	T1250	P1243H	1243	Missense	distal	-7	no	14.822	14.945	EPSD	COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	Q7Z2Z1	TICRR	P24941	CDK2	T1250	A1255V	1255	Missense	distal	5	no	14.822	14.779	EPSD	COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	Q7Z2Z1	TICRR	P24941	CDK2	T1250	P1251Q	1251	Missense	proximal	1	no	14.822	6.910	EPSD	COSMIC	8.148	Loss
CMGC_CDK_CDK2_CDK2_ST	Q7Z2Z1	TICRR	P24941	CDK2	T1260	N1263I	1263	Missense	distal	3	no	12.789	12.683	EPSD	COSMIC;GDSC;CCLE	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	Q7Z2Z1	TICRR	P24941	CDK2	T1260	A1256V	1256	Missense	distal	-4	no	12.789	12.799	EPSD	COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	Q7Z2Z1	TICRR	P24941	CDK2	T1260	Q1267H	1267	Missense	distal	7	no	12.789	13.075	EPSD	COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	Q7Z2Z1	TICRR	P24941	CDK2	T1260	A1255V	1255	Missense	distal	-5	no	12.789	12.795	EPSD	COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	Q7Z2Z1	TICRR	P24941	CDK2	S1303	P1304L	1304	Missense	proximal	1	no	15.541	5.720	EPSD	COSMIC	8.148	Loss
CMGC_CDK_CDK2_CDK2_ST	Q7Z2Z1	TICRR	P24941	CDK2	T1307	P1304L	1304	Missense	distal	-3	no	13.313	13.241	EPSD	COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	Q7Z2Z1	TICRR	P24941	CDK2	S1346	S1346L	1346	Missense	central	0	yes	16.971	0.000	EPSD	COSMIC	8.148	Loss
CMGC_CDK_CDK2_CDK2_ST	Q7Z2Z1	TICRR	P24941	CDK2	T1360	P1356H	1356	Missense	distal	-4	no	13.488	12.884	EPSD	COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	Q7Z2Z1	TICRR	P24941	CDK2	T1360	P1361S	1361	Missense	proximal	1	no	13.488	2.222	EPSD	COSMIC	8.148	Loss
CMGC_CDK_CDK2_CDK2_ST	Q7Z2Z1	TICRR	P24941	CDK2	T1405	T1410I	1410	Missense	distal	5	no	13.966	14.084	EPSD	COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	Q7Z2Z1	TICRR	P24941	CDK2	T1405	T1410A	1410	Missense	distal	5	no	13.966	14.002	EPSD	COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	Q7Z2Z1	TICRR	P24941	CDK2	S1413	T1410I	1410	Missense	distal	-3	no	13.924	13.983	EPSD	COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	Q7Z2Z1	TICRR	P24941	CDK2	S1413	T1410A	1410	Missense	distal	-3	no	13.924	13.905	EPSD	COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	Q7Z2Z1	TICRR	P24941	CDK2	S1430	R1437L	1437	Missense	distal	7	no	13.042	12.583	EPSD	COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	Q7Z2Z1	TICRR	P24941	CDK2	S1430	P1434L	1434	Missense	distal	4	no	13.042	13.154	EPSD	COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	Q7Z2Z1	TICRR	P24941	CDK2	S1433	R1437L	1437	Missense	distal	4	no	15.113	15.345	EPSD	COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	Q7Z2Z1	TICRR	P24941	CDK2	S1433	P1434L	1434	Missense	proximal	1	no	15.113	5.292	EPSD	COSMIC	8.148	Loss
CMGC_CDK_CDK2_CDK2_ST	Q7Z2Z1	TICRR	P24941	CDK2	S1447	P1443H	1443	Missense	distal	-4	no	9.800	9.196	EPSD	COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	Q7Z2Z1	TICRR	P24941	CDK2	S1509	P1511S	1511	Missense	proximal	2	no	14.053	14.119	EPSD	COSMIC;GDSC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	Q7Z2Z1	TICRR	P24941	CDK2	S1509	P1504H	1504	Missense	distal	-5	no	14.053	14.100	EPSD	COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	Q7Z2Z1	TICRR	P24941	CDK2	S1509	P1515S	1515	Missense	distal	6	no	14.053	14.054	EPSD	COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	Q7Z2Z1	TICRR	P24941	CDK2	S1509	P1510S	1510	Missense	proximal	1	no	14.053	2.787	EPSD	COSMIC	8.148	Loss
CMGC_CDK_CDK2_CDK2_ST	Q7Z2Z1	TICRR	P24941	CDK2	S1517	P1511S	1511	Missense	distal	-6	no	14.740	14.739	EPSD	COSMIC;GDSC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	Q7Z2Z1	TICRR	P24941	CDK2	S1517	P1515S	1515	Missense	proximal	-2	no	14.740	14.089	EPSD	COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	Q7Z2Z1	TICRR	P24941	CDK2	S1517	P1510S	1510	Missense	distal	-7	no	14.740	14.560	EPSD	COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	Q7Z2Z1	TICRR	P24941	CDK2	S1555	P1556S	1556	Missense	proximal	1	no	12.375	1.109	EPSD	COSMIC	8.148	Loss
CMGC_CDK_CDK2_CDK2_ST	Q7Z2Z1	TICRR	P24941	CDK2	S1623	S1630F	1630	Missense	distal	7	no	8.531	9.385	EPSD	COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	Q7Z2Z1	TICRR	P24941	CDK2	S1623	Y1621C	1621	Missense	proximal	-2	no	8.531	8.034	EPSD	COSMIC;GDSC;CCLE	8.148	Loss
CMGC_CDK_CDK2_CDK2_ST	Q7Z2Z1	TICRR	P24941	CDK2	T1633	S1630F	1630	Missense	distal	-3	no	14.610	14.702	EPSD	COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	Q7Z2Z1	TICRR	P24941	CDK2	S1718	G1711E	1711	Missense	distal	-7	no	9.198	8.964	EPSD	COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	Q7Z2Z1	TICRR	P24941	CDK2	S1718	H1723Y	1723	Missense	distal	5	no	9.198	9.193	EPSD	COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	Q7Z2Z1	TICRR	P24941	CDK2	T1732	T1732M	1732	Missense	central	0	yes	11.807	0.000	EPSD	COSMIC	8.148	Loss
CMGC_CDK_CDK2_CDK2_ST	Q7Z2Z1	TICRR	P24941	CDK2	T1732	R1731M	1731	Missense	proximal	-1	no	11.807	12.286	EPSD	COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	Q7Z2Z1	TICRR	P24941	CDK2	S1750	D1748Y	1748	Missense	proximal	-2	no	16.013	15.583	EPSD	COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	Q7Z2Z1	TICRR	P24941	CDK2	S1806	A1811S	1811	Missense	distal	5	no	12.714	12.603	EPSD	COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	Q7Z2Z1	TICRR	P24941	CDK2	T1817	S1816F	1816	Missense	proximal	-1	no	7.183	8.439	EPSD	COSMIC	8.148	Gain
CMGC_CDK_CDK2_CDK2_ST	Q7Z2Z1	TICRR	P24941	CDK2	T1817	E1820K	1820	Missense	distal	3	no	7.183	9.268	EPSD	COSMIC	8.148	Gain
CMGC_CDK_CDK2_CDK2_ST	Q7Z2Z1	TICRR	P24941	CDK2	S1881	R1885H	1885	Missense	distal	4	no	13.327	13.210	EPSD	COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	Q7Z2Z1	TICRR	P24941	CDK2	S1881	R1885S	1885	Missense	distal	4	no	13.327	13.461	EPSD	COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	Q7Z2Z1	TICRR	P24941	CDK2	S1884	R1885H	1885	Missense	proximal	1	no	5.771	8.811	EPSD	COSMIC	8.148	Gain
CMGC_CDK_CDK2_CDK2_ST	Q7Z2Z1	TICRR	P24941	CDK2	T1898	R1891H	1891	Missense	distal	-7	no	10.071	9.851	EPSD	COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	Q7Z2Z1	TICRR	P24941	CDK2	T1898	K1900E	1900	Missense	proximal	2	no	10.071	10.309	EPSD	COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	Q7Z2Z1	TICRR	P24941	CDK2	T1898	R1899W	1899	Missense	proximal	1	no	10.071	4.647	EPSD	COSMIC	8.148	Loss
CMGC_CDK_CDK2_CDK2_ST	Q9NP87	POLM	P24941	CDK2	S12	S14N	14	Missense	proximal	2	no	13.841	13.703	EPSD	COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	Q9NP87	POLM	P24941	CDK2	T21	P23L	23	Missense	proximal	2	no	11.040	10.933	EPSD	COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	Q9NP87	POLM	P24941	CDK2	T21	S14N	14	Missense	distal	-7	no	11.040	11.138	EPSD	COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	Q9NP87	POLM	P24941	CDK2	T95	P91L	91	Missense	distal	-4	no	12.319	12.261	EPSD	COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	Q9NP87	POLM	P24941	CDK2	T95	I102R	102	Missense	distal	7	no	12.319	12.752	EPSD	COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	Q9NP87	POLM	P24941	CDK2	S372	S368N	368	Missense	distal	-4	no	15.867	15.651	PhosphoSitePlus	COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	Q9NP87	POLM	P24941	CDK2	S372	T374I	374	Missense	proximal	2	no	15.867	16.022	PhosphoSitePlus	COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	P33991	MCM4	P24941	CDK2	T23	R30S	30	Missense	distal	7	no	12.603	11.961	EPSD	COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	P33991	MCM4	P24941	CDK2	S32	R30S	30	Missense	proximal	-2	no	13.864	14.449	EPSD;PhosphoSitePlus	COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	P33991	MCM4	P24941	CDK2	S61	D66N	66	Missense	distal	5	no	10.740	10.669	EPSD	COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	P33991	MCM4	P24941	CDK2	S71	D66N	66	Missense	distal	-5	no	11.911	11.872	EPSD	COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	P33991	MCM4	P24941	CDK2	S71	P72S	72	Missense	proximal	1	no	11.911	0.645	EPSD	COSMIC	8.148	Loss
CMGC_CDK_CDK2_CDK2_ST	P33991	MCM4	P24941	CDK2	S71	S71I	71	Missense	central	0	yes	11.911	0.000	EPSD	COSMIC	8.148	Loss
CMGC_CDK_CDK2_CDK2_ST	P33991	MCM4	P24941	CDK2	S88	P81T	81	Missense	distal	-7	no	11.564	11.562	EPSD	COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	P33991	MCM4	P24941	CDK2	S88	L82F	82	Missense	distal	-6	no	11.564	11.568	EPSD	COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	P33991	MCM4	P24941	CDK2	S88	Y92N	92	Missense	distal	4	no	11.564	11.345	EPSD	COSMIC;GDSC;CCLE	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	P33991	MCM4	P24941	CDK2	T94	R98W	98	Missense	distal	4	no	13.486	13.126	EPSD	COSMIC;GDSC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	P33991	MCM4	P24941	CDK2	T94	S96G	96	Missense	proximal	2	no	13.486	13.537	EPSD	COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	P33991	MCM4	P24941	CDK2	T94	Y92N	92	Missense	proximal	-2	no	13.486	12.707	EPSD	COSMIC;GDSC;CCLE	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	P33991	MCM4	P24941	CDK2	T102	G106A	106	Missense	distal	4	no	13.992	14.152	EPSD	COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	P33991	MCM4	P24941	CDK2	T102	R98W	98	Missense	distal	-4	no	13.992	13.234	EPSD	COSMIC;GDSC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	P33991	MCM4	P24941	CDK2	T102	S96G	96	Missense	distal	-6	no	13.992	13.995	EPSD	COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	P33991	MCM4	P24941	CDK2	S105	G106A	106	Missense	proximal	1	no	8.680	1.588	EPSD	COSMIC	8.148	Loss
CMGC_CDK_CDK2_CDK2_ST	P33991	MCM4	P24941	CDK2	S105	R98W	98	Missense	distal	-7	no	8.680	8.850	EPSD	COSMIC;GDSC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	P33991	MCM4	P24941	CDK2	T110	G106A	106	Missense	distal	-4	no	15.856	16.115	PhosphoSitePlus;EPSD	COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	P33991	MCM4	P24941	CDK2	S357	K353R	353	Missense	distal	-4	no	12.710	12.548	EPSD	COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	P33991	MCM4	P24941	CDK2	S357	G364R	364	Missense	distal	7	no	12.710	12.530	EPSD	COSMIC;GDSC;CCLE	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	P33991	MCM4	P24941	CDK2	T815	K814T	814	Missense	proximal	-1	no	12.407	12.244	EPSD	COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	P06401	PGR	P24941	CDK2	S20	E22K	22	Missense	proximal	2	no	13.421	13.183	EPSD	COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	P06401	PGR	P24941	CDK2	S20	P21S	21	Missense	proximal	1	no	13.421	2.155	EPSD	COSMIC	8.148	Loss
CMGC_CDK_CDK2_CDK2_ST	P06401	PGR	P24941	CDK2	S20	V23I	23	Missense	distal	3	no	13.421	12.145	EPSD	COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	P06401	PGR	P24941	CDK2	S20	A15V	15	Missense	distal	-5	no	13.421	13.427	EPSD	COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	P06401	PGR	P24941	CDK2	S20	G24V	24	Missense	distal	4	no	13.421	13.768	EPSD	COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	P06401	PGR	P24941	CDK2	S20	P26Q	26	Missense	distal	6	no	13.421	13.427	EPSD	COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	P06401	PGR	P24941	CDK2	S25	P31T	31	Missense	distal	6	no	14.293	14.301	EPSD	COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	P06401	PGR	P24941	CDK2	S25	E22K	22	Missense	distal	-3	no	14.293	14.078	EPSD	COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	P06401	PGR	P24941	CDK2	S25	P21S	21	Missense	distal	-4	no	14.293	14.648	EPSD	COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	P06401	PGR	P24941	CDK2	S25	V23I	23	Missense	proximal	-2	no	14.293	14.789	EPSD	COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	P06401	PGR	P24941	CDK2	S25	G24V	24	Missense	proximal	-1	no	14.293	13.201	EPSD	COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	P06401	PGR	P24941	CDK2	S25	P26Q	26	Missense	proximal	1	no	14.293	6.381	EPSD	COSMIC	8.148	Loss
CMGC_CDK_CDK2_CDK2_ST	P06401	PGR	P24941	CDK2	S102	G97E	97	Missense	distal	-5	no	14.184	14.142	EPSD	COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	P06401	PGR	P24941	CDK2	S102	P103L	103	Missense	proximal	1	no	14.184	4.364	EPSD	COSMIC	8.148	Loss
CMGC_CDK_CDK2_CDK2_ST	P06401	PGR	P24941	CDK2	S102	S99N	99	Missense	distal	-3	no	14.184	14.110	EPSD	COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	P06401	PGR	P24941	CDK2	S102	P103H	103	Missense	proximal	1	no	14.184	7.426	EPSD	COSMIC	8.148	Loss
CMGC_CDK_CDK2_CDK2_ST	P06401	PGR	P24941	CDK2	S130	P131S	131	Missense	proximal	1	no	12.920	1.654	EPSD	COSMIC	8.148	Loss
CMGC_CDK_CDK2_CDK2_ST	P06401	PGR	P24941	CDK2	S130	T137I	137	Missense	distal	7	no	12.920	13.281	EPSD	COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	P06401	PGR	P24941	CDK2	S162	S168F	168	Missense	distal	6	no	13.200	13.181	EPSD;PhosphoSitePlus	COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	P06401	PGR	P24941	CDK2	S162	R167W	167	Missense	distal	5	no	13.200	13.367	EPSD;PhosphoSitePlus	COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	P06401	PGR	P24941	CDK2	S162	M165I	165	Missense	distal	3	no	13.200	12.772	EPSD;PhosphoSitePlus	COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	P06401	PGR	P24941	CDK2	S190	R187W	187	Missense	distal	-3	no	14.476	14.557	EPSD;PhosphoSitePlus	COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	P06401	PGR	P24941	CDK2	S190	R187L	187	Missense	distal	-3	no	14.476	14.216	EPSD;PhosphoSitePlus	COSMIC;CCLE	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	P06401	PGR	P24941	CDK2	S213	A208D	208	Missense	distal	-5	no	14.599	14.632	EPSD;PhosphoSitePlus	COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	P06401	PGR	P24941	CDK2	S213	V219F	219	Missense	distal	6	no	14.599	14.583	EPSD;PhosphoSitePlus	COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	P06401	PGR	P24941	CDK2	S294	V300M	300	Missense	distal	6	no	13.753	13.736	EPSD;PhosphoSitePlus	COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	P06401	PGR	P24941	CDK2	S294	A287V	287	Missense	distal	-7	no	13.753	13.608	EPSD;PhosphoSitePlus	COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	P06401	PGR	P24941	CDK2	S294	A290E	290	Missense	distal	-4	no	13.753	14.042	EPSD;PhosphoSitePlus	COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	P06401	PGR	P24941	CDK2	S294	P291S	291	Missense	distal	-3	no	13.753	13.848	EPSD;PhosphoSitePlus	COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	P06401	PGR	P24941	CDK2	S345	C347G	347	Missense	proximal	2	no	13.491	13.463	EPSD	COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	P06401	PGR	P24941	CDK2	S345	S344T	344	Missense	proximal	-1	no	13.491	13.699	EPSD	COSMIC;GDSC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	P06401	PGR	P24941	CDK2	S345	S349L	349	Missense	distal	4	no	13.491	13.590	EPSD	COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	P06401	PGR	P24941	CDK2	S345	P352L	352	Missense	distal	7	no	13.491	13.522	EPSD	COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	P06401	PGR	P24941	CDK2	S350	S349L	349	Missense	proximal	-1	no	7.938	8.230	EPSD	COSMIC	8.148	Gain
CMGC_CDK_CDK2_CDK2_ST	P06401	PGR	P24941	CDK2	T351	C347G	347	Missense	distal	-4	no	13.300	13.734	EPSD	COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	P06401	PGR	P24941	CDK2	T351	S344T	344	Missense	distal	-7	no	13.300	13.477	EPSD	COSMIC;GDSC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	P06401	PGR	P24941	CDK2	T351	S349L	349	Missense	proximal	-2	no	13.300	13.727	EPSD	COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	P06401	PGR	P24941	CDK2	T351	V353A	353	Missense	proximal	2	no	13.300	13.202	EPSD	COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	P06401	PGR	P24941	CDK2	T351	D357N	357	Missense	distal	6	no	13.300	13.319	EPSD	COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	P06401	PGR	P24941	CDK2	T351	P352L	352	Missense	proximal	1	no	13.300	3.479	EPSD	COSMIC	8.148	Loss
CMGC_CDK_CDK2_CDK2_ST	P06401	PGR	P24941	CDK2	S400	R399C	399	Missense	proximal	-1	no	15.850	15.152	EPSD;PhosphoSitePlus	COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	P06401	PGR	P24941	CDK2	S400	R399S	399	Missense	proximal	-1	no	15.850	14.809	EPSD;PhosphoSitePlus	COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	P06401	PGR	P24941	CDK2	S400	R402C	402	Missense	proximal	2	no	15.850	15.837	EPSD;PhosphoSitePlus	COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	P06401	PGR	P24941	CDK2	S400	P401L	401	Missense	proximal	1	no	15.850	6.029	EPSD;PhosphoSitePlus	COSMIC	8.148	Loss
CMGC_CDK_CDK2_CDK2_ST	P06401	PGR	P24941	CDK2	S400	R402H	402	Missense	proximal	2	no	15.850	15.769	EPSD;PhosphoSitePlus	COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	P06401	PGR	P24941	CDK2	S554	P547L	547	Missense	distal	-7	no	13.084	13.090	EPSD	COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	P06401	PGR	P24941	CDK2	S676	I681M	681	Missense	distal	5	no	15.795	16.010	PhosphoSitePlus;EPSD	COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	P06401	PGR	P24941	CDK2	S676	I681L	681	Missense	distal	5	no	15.795	15.742	PhosphoSitePlus;EPSD	COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	O00571	DDX3X	P24941	CDK2	S58	S57T	57	Missense	proximal	-1	no	7.999	8.207	EPSD	COSMIC	8.148	Gain
CMGC_CDK_CDK2_CDK2_ST	O00571	DDX3X	P24941	CDK2	S76	R79K	79	Missense	distal	3	no	8.384	9.373	EPSD	COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	O00571	DDX3X	P24941	CDK2	S76	G73R	73	Missense	distal	-3	no	8.384	8.469	EPSD	COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	O00571	DDX3X	P24941	CDK2	S78	R79K	79	Missense	proximal	1	no	8.786	0.934	EPSD	COSMIC	8.148	Loss
CMGC_CDK_CDK2_CDK2_ST	O00571	DDX3X	P24941	CDK2	S78	G73R	73	Missense	distal	-5	no	8.786	8.753	EPSD	COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	O00571	DDX3X	P24941	CDK2	S86	G89R	89	Missense	distal	3	no	7.348	9.167	EPSD	COSMIC	8.148	Gain
CMGC_CDK_CDK2_CDK2_ST	O00571	DDX3X	P24941	CDK2	S90	R88C	88	Missense	proximal	-2	no	11.904	12.078	EPSD	COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	O00571	DDX3X	P24941	CDK2	S90	R93K	93	Missense	distal	3	no	11.904	12.893	EPSD	COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	O00571	DDX3X	P24941	CDK2	S90	G89R	89	Missense	proximal	-1	no	11.904	11.426	EPSD	COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	O00571	DDX3X	P24941	CDK2	S90	G94D	94	Missense	distal	4	no	11.904	11.958	EPSD	COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	O00571	DDX3X	P24941	CDK2	S90	S86C	86	Missense	distal	-4	no	11.904	10.797	EPSD	COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	O00571	DDX3X	P24941	CDK2	S92	R88C	88	Missense	distal	-4	no	9.795	9.287	EPSD	COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	O00571	DDX3X	P24941	CDK2	S92	R93K	93	Missense	proximal	1	no	9.795	1.944	EPSD	COSMIC	8.148	Loss
CMGC_CDK_CDK2_CDK2_ST	O00571	DDX3X	P24941	CDK2	S92	G89R	89	Missense	distal	-3	no	9.795	9.880	EPSD	COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	O00571	DDX3X	P24941	CDK2	S92	G94D	94	Missense	proximal	2	no	9.795	9.675	EPSD	COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	O00571	DDX3X	P24941	CDK2	S92	R99T	99	Missense	distal	7	no	9.795	9.002	EPSD	COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	O00571	DDX3X	P24941	CDK2	S92	S86C	86	Missense	distal	-6	no	9.795	9.801	EPSD	COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	O00571	DDX3X	P24941	CDK2	S109	R110P	110	Missense	proximal	1	no	3.716	13.514	EPSD	COSMIC	8.148	Gain
CMGC_CDK_CDK2_CDK2_ST	O00571	DDX3X	P24941	CDK2	S114	R113T	113	Missense	proximal	-1	no	10.774	9.940	EPSD	COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	O00571	DDX3X	P24941	CDK2	S114	R110S	110	Missense	distal	-4	no	10.774	11.371	EPSD	COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	O00571	DDX3X	P24941	CDK2	S114	R121C	121	Missense	distal	7	no	10.774	10.925	EPSD	COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	O00571	DDX3X	P24941	CDK2	S114	R110P	110	Missense	distal	-4	no	10.774	11.017	EPSD	COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	O00571	DDX3X	P24941	CDK2	S114	S109C	109	Missense	distal	-5	no	10.774	10.899	EPSD	COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	O00571	DDX3X	P24941	CDK2	S114	G117D	117	Missense	distal	3	no	10.774	9.061	EPSD	COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	O00571	DDX3X	P24941	CDK2	S114	G115D	115	Missense	proximal	1	no	10.774	9.842	EPSD	COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	O00571	DDX3X	P24941	CDK2	T204	R202L	202	Missense	proximal	-2	no	12.380	13.391	PhosphoSitePlus	COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	O00571	DDX3X	P24941	CDK2	T204	A210G	210	Missense	distal	6	no	12.380	12.373	PhosphoSitePlus	COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	O00571	DDX3X	P24941	CDK2	T226	G229R	229	Missense	distal	3	no	7.102	8.922	EPSD	COSMIC	8.148	Gain
CMGC_CDK_CDK2_CDK2_ST	O00571	DDX3X	P24941	CDK2	T323	G316V	316	Missense	distal	-7	no	15.023	14.718	EPSD	COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	O00571	DDX3X	P24941	CDK2	T323	V321L	321	Missense	proximal	-2	no	15.023	15.449	EPSD	COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	O00571	DDX3X	P24941	CDK2	T323	G316E	316	Missense	distal	-7	no	15.023	14.789	EPSD	COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	O00571	DDX3X	P24941	CDK2	T323	G325E	325	Missense	proximal	2	no	15.023	15.002	EPSD	COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	O00571	DDX3X	P24941	CDK2	T323	L319V	319	Missense	distal	-4	no	15.023	15.033	EPSD	COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	O00571	DDX3X	P24941	CDK2	T323	L320F	320	Missense	distal	-3	no	15.023	15.281	EPSD	COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	O00571	DDX3X	P24941	CDK2	S382	A383P	383	Missense	proximal	1	no	2.410	16.813	EPSD	COSMIC;GDSC;CCLE	8.148	Gain
CMGC_CDK_CDK2_CDK2_ST	O00571	DDX3X	P24941	CDK2	S489	A483G	483	Missense	distal	-6	no	8.315	8.318	EPSD	COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	O00571	DDX3X	P24941	CDK2	S489	G490V	490	Missense	proximal	1	no	8.315	-1.285	EPSD	COSMIC	8.148	Loss
CMGC_CDK_CDK2_CDK2_ST	O00571	DDX3X	P24941	CDK2	S489	R488H	488	Missense	proximal	-1	no	8.315	7.864	EPSD	COSMIC	8.148	Loss
CMGC_CDK_CDK2_CDK2_ST	O00571	DDX3X	P24941	CDK2	S489	G490E	490	Missense	proximal	1	no	8.315	6.461	EPSD	COSMIC	8.148	Loss
CMGC_CDK_CDK2_CDK2_ST	O00571	DDX3X	P24941	CDK2	S489	F487I	487	Missense	proximal	-2	no	8.315	9.274	EPSD	COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	O00571	DDX3X	P24941	CDK2	S489	S492L	492	Missense	distal	3	no	8.315	7.897	EPSD	COSMIC	8.148	Loss
CMGC_CDK_CDK2_CDK2_ST	O00571	DDX3X	P24941	CDK2	S492	G490V	490	Missense	proximal	-2	no	12.554	12.646	EPSD	COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	O00571	DDX3X	P24941	CDK2	S492	R488H	488	Missense	distal	-4	no	12.554	12.193	EPSD	COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	O00571	DDX3X	P24941	CDK2	S492	G490E	490	Missense	proximal	-2	no	12.554	12.181	EPSD	COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	O00571	DDX3X	P24941	CDK2	S492	T498A	498	Missense	distal	6	no	12.554	12.542	EPSD	COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	O00571	DDX3X	P24941	CDK2	S492	F487I	487	Missense	distal	-5	no	12.554	12.521	EPSD	COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	O00571	DDX3X	P24941	CDK2	S492	S492L	492	Missense	central	0	yes	12.554	0.000	EPSD	COSMIC	8.148	Loss
CMGC_CDK_CDK2_CDK2_ST	O00571	DDX3X	P24941	CDK2	S594	R592I	592	Missense	proximal	-2	no	7.235	8.317	EPSD	COSMIC	8.148	Gain
CMGC_CDK_CDK2_CDK2_ST	O00571	DDX3X	P24941	CDK2	S594	R592T	592	Missense	proximal	-2	no	7.235	8.437	EPSD	COSMIC	8.148	Gain
CMGC_CDK_CDK2_CDK2_ST	O00571	DDX3X	P24941	CDK2	S623	G625V	625	Missense	proximal	2	no	8.786	8.791	EPSD	COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	O00571	DDX3X	P24941	CDK2	S623	G624R	624	Missense	proximal	1	no	8.786	6.300	EPSD	COSMIC	8.148	Loss
CMGC_CDK_CDK2_CDK2_ST	O00571	DDX3X	P24941	CDK2	S623	G626V	626	Missense	distal	3	no	8.786	9.495	EPSD	COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	O00571	DDX3X	P24941	CDK2	S623	H628Y	628	Missense	distal	5	no	8.786	8.782	EPSD	COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	O00571	DDX3X	P24941	CDK2	S623	G624D	624	Missense	proximal	1	no	8.786	7.855	EPSD	COSMIC;CCLE	8.148	Loss
CMGC_CDK_CDK2_CDK2_ST	O00571	DDX3X	P24941	CDK2	S623	R622C	622	Missense	proximal	-1	no	8.786	8.088	EPSD	COSMIC	8.148	Loss
CMGC_CDK_CDK2_CDK2_ST	O00571	DDX3X	P24941	CDK2	S623	S630G	630	Missense	distal	7	no	8.786	9.608	EPSD	COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	O00571	DDX3X	P24941	CDK2	S623	R617K	617	Missense	distal	-6	no	8.786	8.784	EPSD	COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	O00571	DDX3X	P24941	CDK2	S623	R617T	617	Missense	distal	-6	no	8.786	8.784	EPSD	COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	O00571	DDX3X	P24941	CDK2	S654	G647E	647	Missense	distal	-7	no	8.626	8.392	EPSD	COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	O00571	DDX3X	P24941	CDK2	S654	N651S	651	Missense	distal	-3	no	8.626	8.701	EPSD	COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	O00571	DDX3X	P24941	CDK2	S654	D658E	658	Missense	distal	4	no	8.626	8.708	EPSD	COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	O00571	DDX3X	P24941	CDK2	S654	Q655R	655	Missense	proximal	1	no	8.626	6.739	EPSD	COSMIC	8.148	Loss
CMGC_CDK_CDK2_CDK2_ST	O00571	DDX3X	P24941	CDK2	S654	Q655H	655	Missense	proximal	1	no	8.626	9.779	EPSD	COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	O00571	DDX3X	P24941	CDK2	S654	N653S	653	Missense	proximal	-1	no	8.626	8.229	EPSD	COSMIC;CCLE	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	O00571	DDX3X	P24941	CDK2	S654	G661C	661	Missense	distal	7	no	8.626	8.597	EPSD	COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	P18858	LIG1	P24941	CDK2	S51	E48K	48	Missense	distal	-3	no	16.386	16.171	EPSD;PhosphoSitePlus	COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	P18858	LIG1	P24941	CDK2	S51	R55S	55	Missense	distal	4	no	16.386	16.520	EPSD;PhosphoSitePlus	COSMIC;GDSC;CCLE	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	P18858	LIG1	P24941	CDK2	S91	P95H	95	Missense	distal	4	no	13.319	13.081	PhosphoSitePlus;EPSD	COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	P18858	LIG1	P24941	CDK2	S98	P95H	95	Missense	distal	-3	no	13.237	13.383	EPSD	COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	P18858	LIG1	P24941	CDK2	S98	N102H	102	Missense	distal	4	no	13.237	13.020	EPSD	COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	P18858	LIG1	P24941	CDK2	S109	P110L	110	Missense	proximal	1	no	9.826	0.005	EPSD	COSMIC	8.148	Loss
CMGC_CDK_CDK2_CDK2_ST	P18858	LIG1	P24941	CDK2	S109	N102H	102	Missense	distal	-7	no	9.826	10.031	EPSD	COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	P18858	LIG1	P24941	CDK2	S114	P110L	110	Missense	distal	-4	no	14.157	14.099	EPSD	COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	P18858	LIG1	P24941	CDK2	S114	P119L	119	Missense	distal	5	no	14.157	14.197	EPSD	COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	P18858	LIG1	P24941	CDK2	T159	K152E	152	Missense	distal	-7	no	13.016	13.153	EPSD	COSMIC;CCLE	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	P18858	LIG1	P24941	CDK2	T159	S163N	163	Missense	distal	4	no	13.016	12.982	EPSD	COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	P18858	LIG1	P24941	CDK2	T159	K161N	161	Missense	proximal	2	no	13.016	13.087	EPSD	COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	P18858	LIG1	P24941	CDK2	T183	P181S	181	Missense	proximal	-2	no	16.795	16.144	EPSD	COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	P18858	LIG1	P24941	CDK2	T233	F231C	231	Missense	proximal	-2	no	16.182	16.233	EPSD;PhosphoSitePlus	COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	P18858	LIG1	P24941	CDK2	T233	P234A	234	Missense	proximal	1	no	16.182	1.779	EPSD;PhosphoSitePlus	COSMIC;GDSC;CCLE	8.148	Loss
CMGC_CDK_CDK2_CDK2_ST	P18858	LIG1	P24941	CDK2	T311	N314K	314	Missense	distal	3	no	4.919	8.190	EPSD	COSMIC	8.148	Gain
CMGC_CDK_CDK2_CDK2_ST	P18858	LIG1	P24941	CDK2	S323	S318I	318	Missense	distal	-5	no	14.421	14.505	EPSD	COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	P18858	LIG1	P24941	CDK2	S419	S419P	419	Missense	central	0	yes	8.606	0.000	EPSD	COSMIC	8.148	Loss
CMGC_CDK_CDK2_CDK2_ST	P18858	LIG1	P24941	CDK2	S419	S417R	417	Missense	proximal	-2	no	8.606	8.022	EPSD	COSMIC	8.148	Loss
CMGC_CDK_CDK2_CDK2_ST	P18858	LIG1	P24941	CDK2	S419	A418T	418	Missense	proximal	-1	no	8.606	8.614	EPSD	COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	P18858	LIG1	P24941	CDK2	S535	P539L	539	Missense	distal	4	no	12.799	12.911	EPSD	COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	P18858	LIG1	P24941	CDK2	S819	S819F	819	Missense	central	0	yes	13.515	0.000	EPSD	COSMIC	8.148	Loss
CMGC_CDK_CDK2_CDK2_ST	P18858	LIG1	P24941	CDK2	S819	V824M	824	Missense	distal	5	no	13.515	13.855	EPSD	COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	P18858	LIG1	P24941	CDK2	S819	S819I	819	Missense	central	0	yes	13.515	0.000	EPSD	COSMIC	8.148	Loss
CMGC_CDK_CDK2_CDK2_ST	P18858	LIG1	P24941	CDK2	S819	P820Q	820	Missense	proximal	1	no	13.515	5.603	EPSD	COSMIC	8.148	Loss
CMGC_CDK_CDK2_CDK2_ST	P18858	LIG1	P24941	CDK2	S901	N905K	905	Missense	distal	4	no	9.483	9.905	EPSD	COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	Q96KS0	EGLN2	P24941	CDK2	S74	G79S	79	Missense	distal	5	no	17.052	16.825	EPSD	COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	Q96KS0	EGLN2	P24941	CDK2	S130	A128D	128	Missense	proximal	-2	no	15.587	15.436	PhosphoSitePlus	COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	Q96KS0	EGLN2	P24941	CDK2	S130	P129L	129	Missense	proximal	-1	no	15.587	15.408	PhosphoSitePlus	COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	Q96KS0	EGLN2	P24941	CDK2	S401	P403Q	403	Missense	proximal	2	no	8.517	8.576	EPSD	COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	Q96KS0	EGLN2	P24941	CDK2	S401	T405M	405	Missense	distal	4	no	8.517	7.813	EPSD	COSMIC;GDSC	8.148	Loss
CMGC_CDK_CDK2_CDK2_ST	Q96KS0	EGLN2	P24941	CDK2	T405	P403Q	403	Missense	proximal	-2	no	9.169	8.602	EPSD	COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	Q96KS0	EGLN2	P24941	CDK2	T405	T405M	405	Missense	central	0	yes	9.169	0.000	EPSD	COSMIC;GDSC	8.148	Loss
CMGC_CDK_CDK2_CDK2_ST	Q9H2G4	TSPYL2	P24941	CDK2	S186	R187G	187	Missense	proximal	1	no	6.546	9.033	EPSD	COSMIC	8.148	Gain
CMGC_CDK_CDK2_CDK2_ST	Q9H2G4	TSPYL2	P24941	CDK2	T340	T340N	340	Missense	central	0	yes	13.338	0.000	PhosphoSitePlus;EPSD	COSMIC	8.148	Loss
CMGC_CDK_CDK2_CDK2_ST	Q9H2G4	TSPYL2	P24941	CDK2	T340	R334W	334	Missense	distal	-6	no	13.338	13.344	PhosphoSitePlus;EPSD	COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	P15923	TCF3	P24941	CDK2	S102	G97R	97	Missense	distal	-5	no	9.422	9.389	EPSD	COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	P15923	TCF3	P24941	CDK2	S102	E104K	104	Missense	proximal	2	no	9.422	9.184	EPSD	COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	P15923	TCF3	P24941	CDK2	S102	R105W	105	Missense	distal	3	no	9.422	6.782	EPSD	COSMIC;GDSC;CCLE	8.148	Loss
CMGC_CDK_CDK2_CDK2_ST	P15923	TCF3	P24941	CDK2	S102	G103S	103	Missense	proximal	1	no	9.422	5.468	EPSD	COSMIC	8.148	Loss
CMGC_CDK_CDK2_CDK2_ST	P15923	TCF3	P24941	CDK2	S102	K101R	101	Missense	proximal	-1	no	9.422	10.092	EPSD	COSMIC;GDSC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	P15923	TCF3	P24941	CDK2	S134	E129K	129	Missense	distal	-5	no	13.345	13.310	EPSD	COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	P15923	TCF3	P24941	CDK2	S134	S139F	139	Missense	distal	5	no	13.345	13.664	EPSD	COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	P15923	TCF3	P24941	CDK2	S134	S141L	141	Missense	distal	7	no	13.345	13.527	EPSD	COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	P15923	TCF3	P24941	CDK2	S134	P135L	135	Missense	proximal	1	no	13.345	3.524	EPSD	COSMIC	8.148	Loss
CMGC_CDK_CDK2_CDK2_ST	P15923	TCF3	P24941	CDK2	S139	S139F	139	Missense	central	0	yes	13.086	0.000	EPSD;PhosphoSitePlus	COSMIC	8.148	Loss
CMGC_CDK_CDK2_CDK2_ST	P15923	TCF3	P24941	CDK2	S139	S141L	141	Missense	proximal	2	no	13.086	12.913	EPSD;PhosphoSitePlus	COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	P15923	TCF3	P24941	CDK2	S139	P135L	135	Missense	distal	-4	no	13.086	13.028	EPSD;PhosphoSitePlus	COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	P15923	TCF3	P24941	CDK2	T205	A203T	203	Missense	proximal	-2	no	14.417	14.368	EPSD	COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	P15923	TCF3	P24941	CDK2	T205	A212T	212	Missense	distal	7	no	14.417	13.729	EPSD	COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	P15923	TCF3	P24941	CDK2	S229	P230S	230	Missense	proximal	1	no	14.122	2.856	EPSD	COSMIC	8.148	Loss
CMGC_CDK_CDK2_CDK2_ST	P15923	TCF3	P24941	CDK2	S245	P248S	248	Missense	distal	3	no	13.859	13.893	PhosphoSitePlus;EPSD	COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	P15923	TCF3	P24941	CDK2	S245	G252S	252	Missense	distal	7	no	13.859	13.037	PhosphoSitePlus;EPSD	COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	P15923	TCF3	P24941	CDK2	S245	S244L	244	Missense	proximal	-1	no	13.859	14.151	PhosphoSitePlus;EPSD	COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	P15923	TCF3	P24941	CDK2	T308	P309L	309	Missense	proximal	1	no	16.249	6.428	EPSD	COSMIC;CCLE	8.148	Loss
CMGC_CDK_CDK2_CDK2_ST	P15923	TCF3	P24941	CDK2	T308	G313V	313	Missense	distal	5	no	16.249	16.089	EPSD	COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	P15923	TCF3	P24941	CDK2	T308	G313R	313	Missense	distal	5	no	16.249	16.228	EPSD	COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	P15923	TCF3	P24941	CDK2	S341	S346N	346	Missense	distal	5	no	16.130	16.334	EPSD	COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	P15923	TCF3	P24941	CDK2	S352	S346N	346	Missense	distal	-6	no	12.332	12.333	EPSD	COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	P15923	TCF3	P24941	CDK2	S352	P353L	353	Missense	proximal	1	no	12.332	2.511	EPSD	COSMIC;CCLE	8.148	Loss
CMGC_CDK_CDK2_CDK2_ST	P15923	TCF3	P24941	CDK2	T355	P353L	353	Missense	proximal	-2	no	12.891	12.667	EPSD	COSMIC;CCLE	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	P15923	TCF3	P24941	CDK2	T355	G362D	362	Missense	distal	7	no	12.891	12.907	EPSD	COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	P15923	TCF3	P24941	CDK2	S359	T366M	366	Missense	distal	7	no	14.031	14.880	EPSD	COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	P15923	TCF3	P24941	CDK2	S359	G362D	362	Missense	distal	3	no	14.031	12.318	EPSD	COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	P15923	TCF3	P24941	CDK2	S367	T366M	366	Missense	proximal	-1	no	7.548	8.861	EPSD	COSMIC	8.148	Gain
CMGC_CDK_CDK2_CDK2_ST	P15923	TCF3	P24941	CDK2	S379	G373R	373	Missense	distal	-6	no	13.318	13.317	EPSD	COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	P15923	TCF3	P24941	CDK2	S379	G385S	385	Missense	distal	6	no	13.318	13.330	EPSD	COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	P15923	TCF3	P24941	CDK2	S379	G385R	385	Missense	distal	6	no	13.318	13.313	EPSD	COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	P15923	TCF3	P24941	CDK2	S529	A523V	523	Missense	distal	-6	no	13.756	13.759	EPSD	COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	P15923	TCF3	P24941	CDK2	S529	P530R	530	Missense	proximal	1	no	13.756	3.958	EPSD	COSMIC;GDSC;CCLE	8.148	Loss
CMGC_CDK_CDK2_CDK2_ST	P15923	TCF3	P24941	CDK2	S529	R527Q	527	Missense	proximal	-2	no	13.756	14.425	EPSD	COSMIC;CCLE	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	P15923	TCF3	P24941	CDK2	S529	E532K	532	Missense	distal	3	no	13.756	15.842	EPSD	COSMIC;GDSC;CCLE	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	P15923	TCF3	P24941	CDK2	S529	R525G	525	Missense	distal	-4	no	13.756	13.681	EPSD	COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	P15923	TCF3	P24941	CDK2	S529	E534K	534	Missense	distal	5	no	13.756	13.623	EPSD	COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	O60271	SPAG9	P24941	CDK2	S194	S190F	190	Missense	distal	-4	no	8.954	7.992	EPSD	COSMIC	8.148	Loss
CMGC_CDK_CDK2_CDK2_ST	O60271	SPAG9	P24941	CDK2	T217	D219H	219	Missense	proximal	2	no	14.361	14.441	EPSD	COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	O60271	SPAG9	P24941	CDK2	T217	G212V	212	Missense	distal	-5	no	14.361	14.312	EPSD	COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	O60271	SPAG9	P24941	CDK2	T226	D219H	219	Missense	distal	-7	no	12.761	12.643	EPSD	COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	O60271	SPAG9	P24941	CDK2	S242	S242Y	242	Missense	central	0	yes	10.039	0.000	EPSD	COSMIC	8.148	Loss
CMGC_CDK_CDK2_CDK2_ST	O60271	SPAG9	P24941	CDK2	S242	R241C	241	Missense	proximal	-1	no	10.039	9.341	EPSD	COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	O60271	SPAG9	P24941	CDK2	S242	S238C	238	Missense	distal	-4	no	10.039	8.933	EPSD	COSMIC;GDSC;CCLE	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	O60271	SPAG9	P24941	CDK2	S251	K256N	256	Missense	distal	5	no	15.066	15.223	EPSD	COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	O60271	SPAG9	P24941	CDK2	T292	D291N	291	Missense	proximal	-1	no	16.757	15.928	EPSD	COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	O60271	SPAG9	P24941	CDK2	T348	E350Q	350	Missense	proximal	2	no	10.726	10.688	EPSD	COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	O60271	SPAG9	P24941	CDK2	T348	E350K	350	Missense	proximal	2	no	10.726	10.488	EPSD	COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	O60271	SPAG9	P24941	CDK2	T348	Q342K	342	Missense	distal	-6	no	10.726	10.723	EPSD	COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	O60271	SPAG9	P24941	CDK2	T348	M353V	353	Missense	distal	5	no	10.726	10.385	EPSD	COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	O60271	SPAG9	P24941	CDK2	T348	V341A	341	Missense	distal	-7	no	10.726	10.871	EPSD	COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	O60271	SPAG9	P24941	CDK2	S358	S358N	358	Missense	central	0	yes	8.280	0.000	EPSD	COSMIC	8.148	Loss
CMGC_CDK_CDK2_CDK2_ST	O60271	SPAG9	P24941	CDK2	S358	D356H	356	Missense	proximal	-2	no	8.280	7.404	EPSD	COSMIC	8.148	Loss
CMGC_CDK_CDK2_CDK2_ST	O60271	SPAG9	P24941	CDK2	S358	S364I	364	Missense	distal	6	no	8.280	8.278	EPSD	COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	O60271	SPAG9	P24941	CDK2	S358	M353V	353	Missense	distal	-5	no	8.280	8.204	EPSD	COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	O60271	SPAG9	P24941	CDK2	T365	E371G	371	Missense	distal	6	no	13.867	13.859	EPSD	COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	O60271	SPAG9	P24941	CDK2	T365	S358N	358	Missense	distal	-7	no	13.867	13.966	EPSD	COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	O60271	SPAG9	P24941	CDK2	T365	S364I	364	Missense	proximal	-1	no	13.867	14.321	EPSD	COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	O60271	SPAG9	P24941	CDK2	S381	E385G	385	Missense	distal	4	no	8.336	8.199	EPSD	COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	O60271	SPAG9	P24941	CDK2	S381	E380D	380	Missense	proximal	-1	no	8.336	8.306	EPSD	COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	O60271	SPAG9	P24941	CDK2	S391	G390V	390	Missense	proximal	-1	no	8.660	7.568	EPSD	COSMIC	8.148	Loss
CMGC_CDK_CDK2_CDK2_ST	O60271	SPAG9	P24941	CDK2	S583	T582M	582	Missense	proximal	-1	no	7.305	8.618	EPSD	COSMIC	8.148	Gain
CMGC_CDK_CDK2_CDK2_ST	O60271	SPAG9	P24941	CDK2	T586	R592T	592	Missense	distal	6	no	15.392	15.416	PhosphoSitePlus	COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	O60271	SPAG9	P24941	CDK2	T586	T582M	582	Missense	distal	-4	no	15.392	14.477	PhosphoSitePlus	COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	O60271	SPAG9	P24941	CDK2	T586	N579D	579	Missense	distal	-7	no	15.392	15.715	PhosphoSitePlus	COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	O60271	SPAG9	P24941	CDK2	T586	P587L	587	Missense	proximal	1	no	15.392	5.571	PhosphoSitePlus	COSMIC	8.148	Loss
CMGC_CDK_CDK2_CDK2_ST	O60271	SPAG9	P24941	CDK2	S597	Q598P	598	Missense	proximal	1	no	6.231	14.142	EPSD	COSMIC	8.148	Gain
CMGC_CDK_CDK2_CDK2_ST	O60271	SPAG9	P24941	CDK2	S815	S822C	822	Missense	distal	7	no	7.387	8.180	EPSD	COSMIC	8.148	Gain
CMGC_CDK_CDK2_CDK2_ST	O60271	SPAG9	P24941	CDK2	S932	V934M	934	Missense	proximal	2	no	11.399	11.487	EPSD	COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	O60271	SPAG9	P24941	CDK2	S932	V925M	925	Missense	distal	-7	no	11.399	11.880	EPSD	COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	O60271	SPAG9	P24941	CDK2	S1238	S1244G	1244	Missense	distal	6	no	13.481	13.469	EPSD	COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	O60271	SPAG9	P24941	CDK2	S1238	I1237F	1237	Missense	proximal	-1	no	13.481	14.284	EPSD	COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	O60271	SPAG9	P24941	CDK2	S1238	S1243G	1243	Missense	distal	5	no	13.481	13.709	EPSD	COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	O60271	SPAG9	P24941	CDK2	S1262	M1269I	1269	Missense	distal	7	no	9.764	9.276	EPSD	COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	O60271	SPAG9	P24941	CDK2	S1262	Q1263R	1263	Missense	proximal	1	no	9.764	7.877	EPSD	COSMIC	8.148	Loss
CMGC_CDK_CDK2_CDK2_ST	O60271	SPAG9	P24941	CDK2	S1262	L1266F	1266	Missense	distal	4	no	9.764	9.469	EPSD	COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	O60271	SPAG9	P24941	CDK2	S1262	E1259Q	1259	Missense	distal	-3	no	9.764	9.647	EPSD	COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	O60271	SPAG9	P24941	CDK2	S1262	T1264M	1264	Missense	proximal	2	no	9.764	10.152	EPSD	COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	O60271	SPAG9	P24941	CDK2	T1264	M1269I	1269	Missense	distal	5	no	18.100	17.885	EPSD	COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	O60271	SPAG9	P24941	CDK2	T1264	V1271A	1271	Missense	distal	7	no	18.100	18.226	EPSD	COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	O60271	SPAG9	P24941	CDK2	T1264	Q1263R	1263	Missense	proximal	-1	no	18.100	18.978	EPSD	COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	O60271	SPAG9	P24941	CDK2	T1264	L1266F	1266	Missense	proximal	2	no	18.100	18.458	EPSD	COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	O60271	SPAG9	P24941	CDK2	T1264	E1259Q	1259	Missense	distal	-5	no	18.100	18.063	EPSD	COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	O60271	SPAG9	P24941	CDK2	T1264	T1264M	1264	Missense	central	0	yes	18.100	0.000	EPSD	COSMIC	8.148	Loss
CMGC_CDK_CDK2_CDK2_ST	Q05516	ZBTB16	P24941	CDK2	S197	D204E	204	Missense	distal	7	no	18.694	18.051	PhosphoSitePlus;EPSD	COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	Q05516	ZBTB16	P24941	CDK2	S197	G192S	192	Missense	distal	-5	no	18.694	18.570	PhosphoSitePlus;EPSD	COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	Q05516	ZBTB16	P24941	CDK2	S253	M246V	246	Missense	distal	-7	no	9.906	9.425	EPSD	COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	Q05516	ZBTB16	P24941	CDK2	S253	V248L	248	Missense	distal	-5	no	9.906	9.887	EPSD	COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	Q05516	ZBTB16	P24941	CDK2	S253	G258E	258	Missense	distal	5	no	9.906	9.859	EPSD	COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	Q05516	ZBTB16	P24941	CDK2	S256	G258E	258	Missense	proximal	2	no	13.701	13.680	EPSD	COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	Q05516	ZBTB16	P24941	CDK2	T282	G279K	279	Missense	distal	-3	no	17.614	17.470	EPSD;PhosphoSitePlus	COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	Q05516	ZBTB16	P24941	CDK2	T569	Y574C	574	Missense	distal	5	no	9.340	9.500	EPSD	COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	Q05516	ZBTB16	P24941	CDK2	T569	R566H	566	Missense	distal	-3	no	9.340	9.297	EPSD	COSMIC;GDSC;CCLE	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	Q05516	ZBTB16	P24941	CDK2	T569	K572N	572	Missense	distal	3	no	9.340	6.070	EPSD	COSMIC	8.148	Loss
CMGC_CDK_CDK2_CDK2_ST	Q05516	ZBTB16	P24941	CDK2	T597	V595A	595	Missense	proximal	-2	no	12.433	13.099	EPSD	COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	P29374	ARID4A	P24941	CDK2	T133	H130Y	130	Missense	distal	-3	no	12.701	12.669	EPSD	COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	P29374	ARID4A	P24941	CDK2	T151	K155N	155	Missense	distal	4	no	9.616	9.195	EPSD	COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	P29374	ARID4A	P24941	CDK2	T151	D153H	153	Missense	proximal	2	no	9.616	9.697	EPSD	COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	P29374	ARID4A	P24941	CDK2	T498	D495E	495	Missense	distal	-3	no	8.702	8.812	EPSD	COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	P29374	ARID4A	P24941	CDK2	T524	K528T	528	Missense	distal	4	no	15.235	15.116	EPSD	COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	P29374	ARID4A	P24941	CDK2	T524	R521I	521	Missense	distal	-3	no	15.235	15.066	EPSD	COSMIC;GDSC;CCLE	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	P29374	ARID4A	P24941	CDK2	S698	D699N	699	Missense	proximal	1	no	8.165	-24.203	EPSD	COSMIC	8.148	Loss
CMGC_CDK_CDK2_CDK2_ST	P29374	ARID4A	P24941	CDK2	S698	E703K	703	Missense	distal	5	no	8.165	8.032	EPSD	COSMIC	8.148	Loss
CMGC_CDK_CDK2_CDK2_ST	P29374	ARID4A	P24941	CDK2	S789	R795K	795	Missense	distal	6	no	12.863	12.888	EPSD	COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	P29374	ARID4A	P24941	CDK2	S864	E866K	866	Missense	proximal	2	no	20.135	19.898	PhosphoSitePlus;EPSD	COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	P29374	ARID4A	P24941	CDK2	S882	S882P	882	Missense	central	0	yes	9.849	0.000	EPSD	COSMIC	8.148	Loss
CMGC_CDK_CDK2_CDK2_ST	P29374	ARID4A	P24941	CDK2	S882	N879D	879	Missense	distal	-3	no	9.849	9.893	EPSD	COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	P29374	ARID4A	P24941	CDK2	S932	L925P	925	Missense	distal	-7	no	15.539	15.533	EPSD	COSMIC;GDSC;CCLE	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	P29374	ARID4A	P24941	CDK2	S1140	K1136T	1136	Missense	distal	-4	no	15.316	15.564	EPSD;PhosphoSitePlus	COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	P29374	ARID4A	P24941	CDK2	S1241	P1242S	1242	Missense	proximal	1	no	16.262	4.996	EPSD	COSMIC	8.148	Loss
CMGC_CDK_CDK2_CDK2_ST	P29374	ARID4A	P24941	CDK2	S1241	S1245L	1245	Missense	distal	4	no	16.262	16.360	EPSD	COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	P29374	ARID4A	P24941	CDK2	S1241	P1242H	1242	Missense	proximal	1	no	16.262	9.503	EPSD	COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	P29374	ARID4A	P24941	CDK2	S1246	P1242S	1242	Missense	distal	-4	no	14.757	15.111	EPSD	COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	P29374	ARID4A	P24941	CDK2	S1246	S1245L	1245	Missense	proximal	-1	no	14.757	15.048	EPSD	COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	P29374	ARID4A	P24941	CDK2	S1246	P1242H	1242	Missense	distal	-4	no	14.757	14.153	EPSD	COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	Q5TZA2	CROCC	P24941	CDK2	T492	P493L	493	Missense	proximal	1	no	12.216	2.395	EPSD	COSMIC	8.148	Loss
CMGC_CDK_CDK2_CDK2_ST	Q5TZA2	CROCC	P24941	CDK2	T492	R491Q	491	Missense	proximal	-1	no	12.216	11.338	EPSD	COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	Q5TZA2	CROCC	P24941	CDK2	T492	P493S	493	Missense	proximal	1	no	12.216	0.950	EPSD	COSMIC	8.148	Loss
CMGC_CDK_CDK2_CDK2_ST	Q5TZA2	CROCC	P24941	CDK2	S494	P493L	493	Missense	proximal	-1	no	15.424	15.244	EPSD	COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	Q5TZA2	CROCC	P24941	CDK2	S494	R491Q	491	Missense	distal	-3	no	15.424	15.293	EPSD	COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	Q5TZA2	CROCC	P24941	CDK2	S494	P493S	493	Missense	proximal	-1	no	15.424	14.953	EPSD	COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	Q5TZA2	CROCC	P24941	CDK2	S500	P493L	493	Missense	distal	-7	no	14.610	14.615	EPSD	COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	Q5TZA2	CROCC	P24941	CDK2	S500	P493S	493	Missense	distal	-7	no	14.610	14.430	EPSD	COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	Q5TZA2	CROCC	P24941	CDK2	S506	P513L	513	Missense	distal	7	no	16.468	16.499	EPSD	COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	Q5TZA2	CROCC	P24941	CDK2	S512	P513L	513	Missense	proximal	1	no	10.715	0.894	EPSD	COSMIC	8.148	Loss
CMGC_CDK_CDK2_CDK2_ST	Q5TZA2	CROCC	P24941	CDK2	S512	A514V	514	Missense	proximal	2	no	10.715	10.813	EPSD	COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	Q5TZA2	CROCC	P24941	CDK2	S516	P513L	513	Missense	distal	-3	no	8.749	8.678	EPSD	COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	Q5TZA2	CROCC	P24941	CDK2	S516	A514V	514	Missense	proximal	-2	no	8.749	8.083	EPSD	COSMIC	8.148	Loss
CMGC_CDK_CDK2_CDK2_ST	Q5TZA2	CROCC	P24941	CDK2	S602	E599G	599	Missense	distal	-3	no	8.174	8.103	EPSD	COSMIC	8.148	Loss
CMGC_CDK_CDK2_CDK2_ST	Q5TZA2	CROCC	P24941	CDK2	S1460	D1464E	1464	Missense	distal	4	no	19.305	19.387	EPSD	COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	Q5TZA2	CROCC	P24941	CDK2	S1476	S1476N	1476	Missense	central	0	yes	14.056	0.000	EPSD	COSMIC	8.148	Loss
CMGC_CDK_CDK2_CDK2_ST	Q5TZA2	CROCC	P24941	CDK2	S1476	P1477S	1477	Missense	proximal	1	no	14.056	2.791	EPSD	COSMIC	8.148	Loss
CMGC_CDK_CDK2_CDK2_ST	Q5TZA2	CROCC	P24941	CDK2	S1476	T1479I	1479	Missense	distal	3	no	14.056	13.503	EPSD	COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	Q5TZA2	CROCC	P24941	CDK2	S1476	G1473R	1473	Missense	distal	-3	no	14.056	14.142	EPSD	COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	Q5TZA2	CROCC	P24941	CDK2	S1483	S1476N	1476	Missense	distal	-7	no	12.727	12.825	EPSD	COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	Q5TZA2	CROCC	P24941	CDK2	S1483	P1477S	1477	Missense	distal	-6	no	12.727	12.726	EPSD	COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	Q5TZA2	CROCC	P24941	CDK2	S1483	T1479I	1479	Missense	distal	-4	no	12.727	12.409	EPSD	COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	Q5TZA2	CROCC	P24941	CDK2	S1496	A1498T	1498	Missense	proximal	2	no	13.906	13.704	EPSD	COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	Q5TZA2	CROCC	P24941	CDK2	S1499	A1498T	1498	Missense	proximal	-1	no	15.359	15.367	EPSD	COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	Q5TZA2	CROCC	P24941	CDK2	T1911	R1908C	1908	Missense	distal	-3	no	8.886	8.800	EPSD	COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	Q5TZA2	CROCC	P24941	CDK2	T1911	A1918T	1918	Missense	distal	7	no	8.886	8.197	EPSD	COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	Q5TZA2	CROCC	P24941	CDK2	S1939	D1946H	1946	Missense	distal	7	no	14.696	14.141	EPSD	COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	Q5TZA2	CROCC	P24941	CDK2	S2009	S2009C	2009	Missense	central	0	yes	16.642	0.000	EPSD	COSMIC;GDSC;CCLE	8.148	Loss
CMGC_CDK_CDK2_CDK2_ST	Q5TZA2	CROCC	P24941	CDK2	S2009	P2010T	2010	Missense	proximal	1	no	16.642	6.685	EPSD	COSMIC	8.148	Loss
CMGC_CDK_CDK2_CDK2_ST	Q04637	EIF4G1	P24941	CDK2	S15	P21L	21	Missense	distal	6	no	12.202	12.204	EPSD	COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	Q04637	EIF4G1	P24941	CDK2	S15	P10S	10	Missense	distal	-5	no	12.202	12.158	EPSD	COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	Q04637	EIF4G1	P24941	CDK2	T43	Q49E	49	Missense	distal	6	no	9.718	9.710	EPSD	COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	Q04637	EIF4G1	P24941	CDK2	T43	R48S	48	Missense	distal	5	no	9.718	9.511	EPSD	COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	Q04637	EIF4G1	P24941	CDK2	T43	P44S	44	Missense	proximal	1	no	9.718	-1.548	EPSD	COSMIC	8.148	Loss
CMGC_CDK_CDK2_CDK2_ST	Q04637	EIF4G1	P24941	CDK2	S134	T136M	136	Missense	proximal	2	no	14.300	14.688	EPSD	COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	Q04637	EIF4G1	P24941	CDK2	S134	G139W	139	Missense	distal	5	no	14.300	14.446	EPSD	COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	Q04637	EIF4G1	P24941	CDK2	S134	P131S	131	Missense	distal	-3	no	14.300	14.395	EPSD	COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	Q04637	EIF4G1	P24941	CDK2	S198	D191G	191	Missense	distal	-7	no	11.187	11.271	EPSD	COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	Q04637	EIF4G1	P24941	CDK2	S198	G199D	199	Missense	proximal	1	no	11.187	10.256	EPSD	COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	Q04637	EIF4G1	P24941	CDK2	S198	S204T	204	Missense	distal	6	no	11.187	11.194	EPSD	COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	Q04637	EIF4G1	P24941	CDK2	S198	R201C	201	Missense	distal	3	no	11.187	4.823	EPSD	COSMIC	8.148	Loss
CMGC_CDK_CDK2_CDK2_ST	Q04637	EIF4G1	P24941	CDK2	S198	R201H	201	Missense	distal	3	no	11.187	10.491	EPSD	COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	Q04637	EIF4G1	P24941	CDK2	S198	D191Y	191	Missense	distal	-7	no	11.187	11.072	EPSD	COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	Q04637	EIF4G1	P24941	CDK2	T205	G199D	199	Missense	distal	-6	no	12.529	12.525	EPSD	COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	Q04637	EIF4G1	P24941	CDK2	T205	P208L	208	Missense	distal	3	no	12.529	12.146	EPSD	COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	Q04637	EIF4G1	P24941	CDK2	T205	S204T	204	Missense	proximal	-1	no	12.529	12.737	EPSD	COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	Q04637	EIF4G1	P24941	CDK2	T205	R201C	201	Missense	distal	-4	no	12.529	12.021	EPSD	COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	Q04637	EIF4G1	P24941	CDK2	T205	R201H	201	Missense	distal	-4	no	12.529	12.169	EPSD	COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	Q04637	EIF4G1	P24941	CDK2	T205	T211M	211	Missense	distal	6	no	12.529	12.503	EPSD	COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	Q04637	EIF4G1	P24941	CDK2	T207	P208L	208	Missense	proximal	1	no	14.540	4.720	EPSD	COSMIC	8.148	Loss
CMGC_CDK_CDK2_CDK2_ST	Q04637	EIF4G1	P24941	CDK2	T207	S204T	204	Missense	distal	-3	no	14.540	14.406	EPSD	COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	Q04637	EIF4G1	P24941	CDK2	T207	G214S	214	Missense	distal	7	no	14.540	13.719	EPSD	COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	Q04637	EIF4G1	P24941	CDK2	T207	R201C	201	Missense	distal	-6	no	14.540	14.544	EPSD	COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	Q04637	EIF4G1	P24941	CDK2	T207	R201H	201	Missense	distal	-6	no	14.540	14.542	EPSD	COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	Q04637	EIF4G1	P24941	CDK2	T207	T211M	211	Missense	distal	4	no	14.540	13.837	EPSD	COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	Q04637	EIF4G1	P24941	CDK2	T223	G221S	221	Missense	proximal	-2	no	15.200	15.291	EPSD	COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	Q04637	EIF4G1	P24941	CDK2	T223	I229N	229	Missense	distal	6	no	15.200	15.204	EPSD	COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	Q04637	EIF4G1	P24941	CDK2	T223	T223M	223	Missense	central	0	yes	15.200	0.000	EPSD	COSMIC	8.148	Loss
CMGC_CDK_CDK2_CDK2_ST	Q04637	EIF4G1	P24941	CDK2	S253	E256K	256	Missense	distal	3	no	11.891	13.976	EPSD	COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	Q04637	EIF4G1	P24941	CDK2	S253	P250S	250	Missense	distal	-3	no	11.891	11.986	EPSD	COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	Q04637	EIF4G1	P24941	CDK2	S253	S260L	260	Missense	distal	7	no	11.891	12.073	EPSD	COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	Q04637	EIF4G1	P24941	CDK2	S253	G249C	249	Missense	distal	-4	no	11.891	11.457	EPSD	COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	Q04637	EIF4G1	P24941	CDK2	S253	P248S	248	Missense	distal	-5	no	11.891	11.846	EPSD	COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	Q04637	EIF4G1	P24941	CDK2	S253	S255L	255	Missense	proximal	2	no	11.891	11.717	EPSD	COSMIC;GDSC;CCLE	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	Q04637	EIF4G1	P24941	CDK2	S261	E256K	256	Missense	distal	-5	no	15.733	15.698	EPSD	COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	Q04637	EIF4G1	P24941	CDK2	S261	T265K	265	Missense	distal	4	no	15.733	15.851	EPSD	COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	Q04637	EIF4G1	P24941	CDK2	S261	S260L	260	Missense	proximal	-1	no	15.733	16.024	EPSD	COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	Q04637	EIF4G1	P24941	CDK2	S261	P264S	264	Missense	distal	3	no	15.733	15.767	EPSD	COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	Q04637	EIF4G1	P24941	CDK2	S261	P266S	266	Missense	distal	5	no	15.733	15.632	EPSD	COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	Q04637	EIF4G1	P24941	CDK2	S261	S255L	255	Missense	distal	-6	no	15.733	15.734	EPSD	COSMIC;GDSC;CCLE	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	Q04637	EIF4G1	P24941	CDK2	S263	P270S	270	Missense	distal	7	no	12.604	12.452	EPSD	COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	Q04637	EIF4G1	P24941	CDK2	S263	E256K	256	Missense	distal	-7	no	12.604	12.466	EPSD	COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	Q04637	EIF4G1	P24941	CDK2	S263	T265K	265	Missense	proximal	2	no	12.604	12.640	EPSD	COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	Q04637	EIF4G1	P24941	CDK2	S263	S260L	260	Missense	distal	-3	no	12.604	12.437	EPSD	COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	Q04637	EIF4G1	P24941	CDK2	S263	S269Y	269	Missense	distal	6	no	12.604	12.595	EPSD	COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	Q04637	EIF4G1	P24941	CDK2	S263	P264S	264	Missense	proximal	1	no	12.604	1.338	EPSD	COSMIC	8.148	Loss
CMGC_CDK_CDK2_CDK2_ST	Q04637	EIF4G1	P24941	CDK2	S263	P266S	266	Missense	distal	3	no	12.604	12.638	EPSD	COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	Q04637	EIF4G1	P24941	CDK2	S263	S269F	269	Missense	distal	6	no	12.604	12.585	EPSD	COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	Q04637	EIF4G1	P24941	CDK2	T265	P270S	270	Missense	distal	5	no	12.353	12.252	EPSD	COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	Q04637	EIF4G1	P24941	CDK2	T265	T265K	265	Missense	central	0	yes	12.353	0.000	EPSD	COSMIC	8.148	Loss
CMGC_CDK_CDK2_CDK2_ST	Q04637	EIF4G1	P24941	CDK2	T265	S260L	260	Missense	distal	-5	no	12.353	12.409	EPSD	COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	Q04637	EIF4G1	P24941	CDK2	T265	S269Y	269	Missense	distal	4	no	12.353	12.539	EPSD	COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	Q04637	EIF4G1	P24941	CDK2	T265	P264S	264	Missense	proximal	-1	no	12.353	11.882	EPSD	COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	Q04637	EIF4G1	P24941	CDK2	T265	P266S	266	Missense	proximal	1	no	12.353	1.087	EPSD	COSMIC	8.148	Loss
CMGC_CDK_CDK2_CDK2_ST	Q04637	EIF4G1	P24941	CDK2	T265	S269F	269	Missense	distal	4	no	12.353	12.157	EPSD	COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	Q04637	EIF4G1	P24941	CDK2	S267	P270S	270	Missense	distal	3	no	15.468	15.502	EPSD	COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	Q04637	EIF4G1	P24941	CDK2	S267	T265K	265	Missense	proximal	-2	no	15.468	14.987	EPSD	COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	Q04637	EIF4G1	P24941	CDK2	S267	P274S	274	Missense	distal	7	no	15.468	15.316	EPSD	COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	Q04637	EIF4G1	P24941	CDK2	S267	S260L	260	Missense	distal	-7	no	15.468	15.653	EPSD	COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	Q04637	EIF4G1	P24941	CDK2	S267	S269Y	269	Missense	proximal	2	no	15.468	15.459	EPSD	COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	Q04637	EIF4G1	P24941	CDK2	S267	P264S	264	Missense	distal	-3	no	15.468	15.563	EPSD	COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	Q04637	EIF4G1	P24941	CDK2	S267	P266S	266	Missense	proximal	-1	no	15.468	14.997	EPSD	COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	Q04637	EIF4G1	P24941	CDK2	S267	S269F	269	Missense	proximal	2	no	15.468	15.652	EPSD	COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	Q04637	EIF4G1	P24941	CDK2	S269	S276Y	276	Missense	distal	7	no	12.274	12.695	EPSD	COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	Q04637	EIF4G1	P24941	CDK2	S269	S276F	276	Missense	distal	7	no	12.274	13.127	EPSD	COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	Q04637	EIF4G1	P24941	CDK2	S269	P270S	270	Missense	proximal	1	no	12.274	1.008	EPSD	COSMIC	8.148	Loss
CMGC_CDK_CDK2_CDK2_ST	Q04637	EIF4G1	P24941	CDK2	S269	T265K	265	Missense	distal	-4	no	12.274	12.026	EPSD	COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	Q04637	EIF4G1	P24941	CDK2	S269	P274S	274	Missense	distal	5	no	12.274	12.173	EPSD	COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	Q04637	EIF4G1	P24941	CDK2	S269	S269Y	269	Missense	central	0	yes	12.274	0.000	EPSD	COSMIC	8.148	Loss
CMGC_CDK_CDK2_CDK2_ST	Q04637	EIF4G1	P24941	CDK2	S269	P264S	264	Missense	distal	-5	no	12.274	12.229	EPSD	COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	Q04637	EIF4G1	P24941	CDK2	S269	P266S	266	Missense	distal	-3	no	12.274	12.369	EPSD	COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	Q04637	EIF4G1	P24941	CDK2	S269	S269F	269	Missense	central	0	yes	12.274	0.000	EPSD	COSMIC	8.148	Loss
CMGC_CDK_CDK2_CDK2_ST	Q04637	EIF4G1	P24941	CDK2	T301	E306D	306	Missense	distal	5	no	11.596	11.691	EPSD	COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	Q04637	EIF4G1	P24941	CDK2	T301	E298D	298	Missense	distal	-3	no	11.596	11.486	EPSD	COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	Q04637	EIF4G1	P24941	CDK2	T301	E299D	299	Missense	proximal	-2	no	11.596	12.577	EPSD	COSMIC;GDSC;CCLE	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	Q04637	EIF4G1	P24941	CDK2	T301	S300L	300	Missense	proximal	-1	no	11.596	11.888	EPSD	COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	Q04637	EIF4G1	P24941	CDK2	S314	P315S	315	Missense	proximal	1	no	13.252	1.986	EPSD	COSMIC	8.148	Loss
CMGC_CDK_CDK2_CDK2_ST	Q04637	EIF4G1	P24941	CDK2	S314	R312H	312	Missense	proximal	-2	no	13.252	13.478	EPSD	COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	Q04637	EIF4G1	P24941	CDK2	T318	E322K	322	Missense	distal	4	no	12.217	12.601	EPSD	COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	Q04637	EIF4G1	P24941	CDK2	T318	P315S	315	Missense	distal	-3	no	12.217	12.312	EPSD	COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	Q04637	EIF4G1	P24941	CDK2	T318	R312H	312	Missense	distal	-6	no	12.217	12.218	EPSD	COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	Q04637	EIF4G1	P24941	CDK2	S343	P350L	350	Missense	distal	7	no	15.531	15.562	EPSD	COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	Q04637	EIF4G1	P24941	CDK2	S343	P350H	350	Missense	distal	7	no	15.531	15.663	EPSD	COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	Q04637	EIF4G1	P24941	CDK2	S343	S341Y	341	Missense	proximal	-2	no	15.531	15.618	EPSD	COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	Q04637	EIF4G1	P24941	CDK2	S343	L345F	345	Missense	proximal	2	no	15.531	15.889	EPSD	COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	Q04637	EIF4G1	P24941	CDK2	S343	P344S	344	Missense	proximal	1	no	15.531	4.265	EPSD	COSMIC	8.148	Loss
CMGC_CDK_CDK2_CDK2_ST	Q04637	EIF4G1	P24941	CDK2	T349	P350L	350	Missense	proximal	1	no	13.169	3.348	EPSD	COSMIC	8.148	Loss
CMGC_CDK_CDK2_CDK2_ST	Q04637	EIF4G1	P24941	CDK2	T349	P350H	350	Missense	proximal	1	no	13.169	6.410	EPSD	COSMIC	8.148	Loss
CMGC_CDK_CDK2_CDK2_ST	Q04637	EIF4G1	P24941	CDK2	T349	S353C	353	Missense	distal	4	no	13.169	12.408	EPSD	COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	Q04637	EIF4G1	P24941	CDK2	T349	L345F	345	Missense	distal	-4	no	13.169	12.619	EPSD	COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	Q04637	EIF4G1	P24941	CDK2	T349	P344S	344	Missense	distal	-5	no	13.169	13.124	EPSD	COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	Q04637	EIF4G1	P24941	CDK2	S409	S416L	416	Missense	distal	7	no	14.565	14.748	EPSD	COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	Q04637	EIF4G1	P24941	CDK2	S409	D414N	414	Missense	distal	5	no	14.565	14.494	EPSD	COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	Q04637	EIF4G1	P24941	CDK2	S409	P408S	408	Missense	proximal	-1	no	14.565	14.094	EPSD	COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	Q04637	EIF4G1	P24941	CDK2	S409	G406V	406	Missense	distal	-3	no	14.565	14.604	EPSD	COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	Q04637	EIF4G1	P24941	CDK2	S409	L404F	404	Missense	distal	-5	no	14.565	14.626	EPSD	COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	Q04637	EIF4G1	P24941	CDK2	S409	A407D	407	Missense	proximal	-2	no	14.565	14.414	EPSD	COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	Q04637	EIF4G1	P24941	CDK2	S409	S409L	409	Missense	central	0	yes	14.565	0.000	EPSD	COSMIC	8.148	Loss
CMGC_CDK_CDK2_CDK2_ST	Q04637	EIF4G1	P24941	CDK2	S409	A412S	412	Missense	distal	3	no	14.565	15.111	EPSD	COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	Q04637	EIF4G1	P24941	CDK2	S416	S416L	416	Missense	central	0	yes	11.231	0.000	EPSD	COSMIC	8.148	Loss
CMGC_CDK_CDK2_CDK2_ST	Q04637	EIF4G1	P24941	CDK2	S416	D414N	414	Missense	proximal	-2	no	11.231	10.023	EPSD	COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	Q04637	EIF4G1	P24941	CDK2	S416	E422Q	422	Missense	distal	6	no	11.231	11.239	EPSD	COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	Q04637	EIF4G1	P24941	CDK2	S416	S409L	409	Missense	distal	-7	no	11.231	11.416	EPSD	COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	Q04637	EIF4G1	P24941	CDK2	S416	A412S	412	Missense	distal	-4	no	11.231	11.644	EPSD	COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	Q04637	EIF4G1	P24941	CDK2	T441	A440V	440	Missense	proximal	-1	no	12.103	12.330	EPSD	COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	Q04637	EIF4G1	P24941	CDK2	T441	T436K	436	Missense	distal	-5	no	12.103	12.107	EPSD	COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	Q04637	EIF4G1	P24941	CDK2	T441	P434L	434	Missense	distal	-7	no	12.103	12.109	EPSD	COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	Q04637	EIF4G1	P24941	CDK2	T441	T444M	444	Missense	distal	3	no	12.103	11.977	EPSD	COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	Q04637	EIF4G1	P24941	CDK2	T441	P434S	434	Missense	distal	-7	no	12.103	11.923	EPSD	COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	Q04637	EIF4G1	P24941	CDK2	T441	S439F	439	Missense	proximal	-2	no	12.103	11.641	EPSD	COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	Q04637	EIF4G1	P24941	CDK2	T441	P446S	446	Missense	distal	5	no	12.103	12.002	EPSD	COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	Q04637	EIF4G1	P24941	CDK2	S450	M457I	457	Missense	distal	7	no	14.527	14.039	EPSD	COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	Q04637	EIF4G1	P24941	CDK2	S450	M457V	457	Missense	distal	7	no	14.527	14.240	EPSD	COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	Q04637	EIF4G1	P24941	CDK2	S450	E455D	455	Missense	distal	5	no	14.527	14.621	EPSD	COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	Q04637	EIF4G1	P24941	CDK2	S450	T444M	444	Missense	distal	-6	no	14.527	14.534	EPSD	COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	Q04637	EIF4G1	P24941	CDK2	S450	A452S	452	Missense	proximal	2	no	14.527	14.569	EPSD	COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	Q04637	EIF4G1	P24941	CDK2	S450	P446S	446	Missense	distal	-4	no	14.527	14.881	EPSD	COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	Q04637	EIF4G1	P24941	CDK2	S450	S450F	450	Missense	central	0	yes	14.527	0.000	EPSD	COSMIC	8.148	Loss
CMGC_CDK_CDK2_CDK2_ST	Q04637	EIF4G1	P24941	CDK2	S450	E456G	456	Missense	distal	6	no	14.527	14.518	EPSD	COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	Q04637	EIF4G1	P24941	CDK2	T489	A493T	493	Missense	distal	4	no	11.968	12.211	EPSD	COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	Q04637	EIF4G1	P24941	CDK2	T489	I491T	491	Missense	proximal	2	no	11.968	11.814	EPSD	COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	Q04637	EIF4G1	P24941	CDK2	T489	P492Q	492	Missense	distal	3	no	11.968	11.943	EPSD	COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	Q04637	EIF4G1	P24941	CDK2	T647	R650W	650	Missense	distal	3	no	15.808	13.168	PhosphoSitePlus	COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	Q04637	EIF4G1	P24941	CDK2	T647	K643R	643	Missense	distal	-4	no	15.808	15.646	PhosphoSitePlus	COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	Q04637	EIF4G1	P24941	CDK2	T647	K643T	643	Missense	distal	-4	no	15.808	16.055	PhosphoSitePlus	COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	Q04637	EIF4G1	P24941	CDK2	T647	K643N	643	Missense	distal	-4	no	15.808	16.027	PhosphoSitePlus	COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	Q04637	EIF4G1	P24941	CDK2	T647	K643M	643	Missense	distal	-4	no	15.808	15.141	PhosphoSitePlus	COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	Q04637	EIF4G1	P24941	CDK2	T647	R650Q	650	Missense	distal	3	no	15.808	14.065	PhosphoSitePlus	COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	Q04637	EIF4G1	P24941	CDK2	T667	N661H	661	Missense	distal	-6	no	15.825	15.829	EPSD	COSMIC;GDSC;CCLE	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	Q04637	EIF4G1	P24941	CDK2	T667	D665Y	665	Missense	proximal	-2	no	15.825	15.395	EPSD	COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	Q04637	EIF4G1	P24941	CDK2	T667	P668A	668	Missense	proximal	1	no	15.825	1.421	EPSD	COSMIC	8.148	Loss
CMGC_CDK_CDK2_CDK2_ST	Q04637	EIF4G1	P24941	CDK2	T667	P668L	668	Missense	proximal	1	no	15.825	6.004	EPSD	COSMIC	8.148	Loss
CMGC_CDK_CDK2_CDK2_ST	Q04637	EIF4G1	P24941	CDK2	T667	D665N	665	Missense	proximal	-2	no	15.825	14.617	EPSD	COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	Q04637	EIF4G1	P24941	CDK2	T667	P668Q	668	Missense	proximal	1	no	15.825	7.913	EPSD	COSMIC	8.148	Loss
CMGC_CDK_CDK2_CDK2_ST	Q04637	EIF4G1	P24941	CDK2	T667	P664T	664	Missense	distal	-3	no	15.825	15.785	EPSD	COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	Q04637	EIF4G1	P24941	CDK2	T680	R681H	681	Missense	proximal	1	no	5.293	8.333	EPSD	COSMIC	8.148	Gain
CMGC_CDK_CDK2_CDK2_ST	Q04637	EIF4G1	P24941	CDK2	S895	L896P	896	Missense	proximal	1	no	6.545	16.365	EPSD	COSMIC	8.148	Gain
CMGC_CDK_CDK2_CDK2_ST	Q04637	EIF4G1	P24941	CDK2	S1041	R1042H	1042	Missense	proximal	1	no	7.032	10.071	EPSD	COSMIC	8.148	Gain
CMGC_CDK_CDK2_CDK2_ST	Q04637	EIF4G1	P24941	CDK2	S1041	L1044R	1044	Missense	distal	3	no	7.032	9.134	EPSD	COSMIC	8.148	Gain
CMGC_CDK_CDK2_CDK2_ST	Q04637	EIF4G1	P24941	CDK2	T1066	S1067P	1067	Missense	proximal	1	no	3.443	14.709	EPSD	COSMIC	8.148	Gain
CMGC_CDK_CDK2_CDK2_ST	Q04637	EIF4G1	P24941	CDK2	S1101	G1102R	1102	Missense	proximal	1	no	10.860	8.374	EPSD	COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	Q04637	EIF4G1	P24941	CDK2	S1101	P1105H	1105	Missense	distal	4	no	10.860	10.623	EPSD	COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	Q04637	EIF4G1	P24941	CDK2	S1101	G1096D	1096	Missense	distal	-5	no	10.860	10.838	EPSD	COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	Q04637	EIF4G1	P24941	CDK2	S1101	A1108T	1108	Missense	distal	7	no	10.860	10.172	EPSD	COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	Q04637	EIF4G1	P24941	CDK2	S1101	S1097I	1097	Missense	distal	-4	no	10.860	10.355	EPSD	COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	Q04637	EIF4G1	P24941	CDK2	S1101	S1106P	1106	Missense	distal	5	no	10.860	10.961	EPSD	COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	Q04637	EIF4G1	P24941	CDK2	S1101	A1103P	1103	Missense	proximal	2	no	10.860	10.836	EPSD	COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	Q04637	EIF4G1	P24941	CDK2	S1101	S1098I	1098	Missense	distal	-3	no	10.860	10.785	EPSD	COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	Q04637	EIF4G1	P24941	CDK2	S1147	R1148Q	1148	Missense	proximal	1	no	7.731	9.618	EPSD	COSMIC	8.148	Gain
CMGC_CDK_CDK2_CDK2_ST	Q04637	EIF4G1	P24941	CDK2	T1179	R1173W	1173	Missense	distal	-6	no	15.298	15.304	EPSD	COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	Q04637	EIF4G1	P24941	CDK2	T1179	T1182I	1182	Missense	distal	3	no	15.298	14.745	EPSD	COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	Q04637	EIF4G1	P24941	CDK2	T1179	A1177G	1177	Missense	proximal	-2	no	15.298	14.540	EPSD	COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	Q04637	EIF4G1	P24941	CDK2	T1179	D1175Y	1175	Missense	distal	-4	no	15.298	15.237	EPSD	COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	Q04637	EIF4G1	P24941	CDK2	T1179	A1177V	1177	Missense	proximal	-2	no	15.298	14.633	EPSD	COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	Q04637	EIF4G1	P24941	CDK2	T1179	R1176C	1176	Missense	distal	-3	no	15.298	15.213	EPSD	COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	Q04637	EIF4G1	P24941	CDK2	T1179	R1178W	1178	Missense	proximal	-1	no	15.298	15.853	EPSD	COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	Q04637	EIF4G1	P24941	CDK2	T1179	L1174F	1174	Missense	distal	-5	no	15.298	15.359	EPSD	COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	Q04637	EIF4G1	P24941	CDK2	S1231	A1236V	1236	Missense	distal	5	no	17.461	17.418	EPSD	COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	Q04637	EIF4G1	P24941	CDK2	S1231	A1226D	1226	Missense	distal	-5	no	17.461	17.494	EPSD	COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	Q04637	EIF4G1	P24941	CDK2	S1231	A1225S	1225	Missense	distal	-6	no	17.461	17.462	EPSD	COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	Q04637	EIF4G1	P24941	CDK2	S1231	A1236T	1236	Missense	distal	5	no	17.461	17.426	EPSD	COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	Q04637	EIF4G1	P24941	CDK2	S1231	S1238C	1238	Missense	distal	7	no	17.461	18.254	EPSD	COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	Q04637	EIF4G1	P24941	CDK2	S1231	A1235V	1235	Missense	distal	4	no	17.461	17.648	EPSD	COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	Q04637	EIF4G1	P24941	CDK2	S1231	A1226S	1226	Missense	distal	-5	no	17.461	17.392	EPSD	COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	Q04637	EIF4G1	P24941	CDK2	S1271	I1277F	1277	Missense	distal	6	no	14.205	14.187	EPSD	COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	Q04637	EIF4G1	P24941	CDK2	S1271	S1273F	1273	Missense	proximal	2	no	14.205	14.390	EPSD	COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	Q04637	EIF4G1	P24941	CDK2	S1271	V1266M	1266	Missense	distal	-5	no	14.205	14.281	EPSD	COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	Q04637	EIF4G1	P24941	CDK2	S1271	L1275F	1275	Missense	distal	4	no	14.205	13.911	EPSD	COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	Q04637	EIF4G1	P24941	CDK2	S1271	A1270T	1270	Missense	proximal	-1	no	14.205	14.212	EPSD	COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	Q04637	EIF4G1	P24941	CDK2	S1271	S1273P	1273	Missense	proximal	2	no	14.205	14.139	EPSD	COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	Q04637	EIF4G1	P24941	CDK2	T1495	I1491V	1491	Missense	distal	-4	no	16.508	16.611	EPSD	COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	Q04637	EIF4G1	P24941	CDK2	T1495	P1496L	1496	Missense	proximal	1	no	16.508	6.687	EPSD	COSMIC	8.148	Loss
CMGC_CDK_CDK2_CDK2_ST	Q04637	EIF4G1	P24941	CDK2	T1495	I1491T	1491	Missense	distal	-4	no	16.508	16.825	EPSD	COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	Q04637	EIF4G1	P24941	CDK2	T1495	I1491N	1491	Missense	distal	-4	no	16.508	16.797	EPSD	COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	Q04637	EIF4G1	P24941	CDK2	T1495	D1500G	1500	Missense	distal	5	no	16.508	16.461	EPSD	COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	Q04637	EIF4G1	P24941	CDK2	T1495	I1492N	1492	Missense	distal	-3	no	16.508	16.509	EPSD	COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	Q04637	EIF4G1	P24941	CDK2	T1495	I1492T	1492	Missense	distal	-3	no	16.508	16.449	EPSD	COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	Q04637	EIF4G1	P24941	CDK2	T1495	I1492V	1492	Missense	distal	-3	no	16.508	16.631	EPSD	COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	Q04637	EIF4G1	P24941	CDK2	T1495	T1495N	1495	Missense	central	0	yes	16.508	0.000	EPSD	COSMIC	8.148	Loss
CMGC_CDK_CDK2_CDK2_ST	Q9ULX3	NOB1	P24941	CDK2	T42	R43H	43	Missense	proximal	1	no	6.732	9.772	EPSD	COSMIC;CCLE	8.148	Gain
CMGC_CDK_CDK2_CDK2_ST	Q9ULX3	NOB1	P24941	CDK2	T121	T121I	121	Missense	central	0	yes	15.041	0.000	PhosphoSitePlus	COSMIC	8.148	Loss
CMGC_CDK_CDK2_CDK2_ST	Q9ULX3	NOB1	P24941	CDK2	S126	T121I	121	Missense	distal	-5	no	8.246	8.286	EPSD	COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	Q9ULX3	NOB1	P24941	CDK2	T210	I214V	214	Missense	distal	4	no	13.370	13.626	EPSD	COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	Q9ULX3	NOB1	P24941	CDK2	T210	G206V	206	Missense	distal	-4	no	13.370	13.640	EPSD	COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	Q9ULX3	NOB1	P24941	CDK2	T328	G321S	321	Missense	distal	-7	no	13.292	12.787	EPSD	COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	Q9ULX3	NOB1	P24941	CDK2	S371	D377Y	377	Missense	distal	6	no	12.557	12.564	EPSD	COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	Q9ULX3	NOB1	P24941	CDK2	S371	A368T	368	Missense	distal	-3	no	12.557	12.576	EPSD	COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	Q9NRH3	TUBG2	P24941	CDK2	S32	A27T	27	Missense	distal	-5	no	11.518	11.492	EPSD	COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	Q9NRH3	TUBG2	P24941	CDK2	S364	P365L	365	Missense	proximal	1	no	10.936	1.116	EPSD	COSMIC	8.148	Loss
CMGC_CDK_CDK2_CDK2_ST	Q16204	CCDC6	P24941	CDK2	S52	L59F	59	Missense	distal	7	no	13.550	14.222	EPSD	COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	Q16204	CCDC6	P24941	CDK2	S52	K45E	45	Missense	distal	-7	no	13.550	13.688	EPSD	COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	Q16204	CCDC6	P24941	CDK2	S244	P242S	242	Missense	proximal	-2	no	14.569	13.918	PhosphoSitePlus	COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	Q16204	CCDC6	P24941	CDK2	S244	V239A	239	Missense	distal	-5	no	14.569	14.563	PhosphoSitePlus	COSMIC;GDSC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	Q16204	CCDC6	P24941	CDK2	S395	V400M	400	Missense	distal	5	no	13.293	13.633	EPSD	COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	Q16204	CCDC6	P24941	CDK2	S395	L398F	398	Missense	distal	3	no	13.293	13.635	EPSD	COSMIC;GDSC;CCLE	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	Q16204	CCDC6	P24941	CDK2	S413	S406F	406	Missense	distal	-7	no	13.460	14.011	EPSD	COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	Q16204	CCDC6	P24941	CDK2	S413	R415W	415	Missense	proximal	2	no	13.460	13.557	EPSD	COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	Q16204	CCDC6	P24941	CDK2	S413	P412H	412	Missense	proximal	-1	no	13.460	13.579	EPSD	COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	Q16204	CCDC6	P24941	CDK2	S419	R415W	415	Missense	distal	-4	no	16.162	15.404	EPSD	COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	Q16204	CCDC6	P24941	CDK2	S419	P412H	412	Missense	distal	-7	no	16.162	16.285	EPSD	COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	Q16204	CCDC6	P24941	CDK2	S419	R425Q	425	Missense	distal	6	no	16.162	16.184	EPSD	COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	Q16204	CCDC6	P24941	CDK2	T427	S431F	431	Missense	distal	4	no	10.712	10.517	EPSD	COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	Q16204	CCDC6	P24941	CDK2	T427	R425Q	425	Missense	proximal	-2	no	10.712	11.381	EPSD	COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	Q16204	CCDC6	P24941	CDK2	S431	S431F	431	Missense	central	0	yes	14.185	0.000	EPSD	COSMIC	8.148	Loss
CMGC_CDK_CDK2_CDK2_ST	Q16204	CCDC6	P24941	CDK2	S431	R425Q	425	Missense	distal	-6	no	14.185	14.186	EPSD	COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	Q16204	CCDC6	P24941	CDK2	T436	P441S	441	Missense	distal	5	no	13.555	13.454	EPSD	COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	Q16204	CCDC6	P24941	CDK2	T436	S431F	431	Missense	distal	-5	no	13.555	13.672	EPSD	COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	Q16204	CCDC6	P24941	CDK2	T462	T462A	462	Missense	central	0	yes	12.911	0.000	EPSD	COSMIC	8.148	Loss
CMGC_CDK_CDK2_CDK2_ST	Q16204	CCDC6	P24941	CDK2	T462	S467L	467	Missense	distal	5	no	12.911	13.052	EPSD	COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	Q16204	CCDC6	P24941	CDK2	T462	P463S	463	Missense	proximal	1	no	12.911	1.645	EPSD	COSMIC	8.148	Loss
CMGC_CDK_CDK2_CDK2_ST	Q12959	DLG1	P24941	CDK2	T115	I121V	121	Missense	distal	6	no	14.720	14.718	EPSD	COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	Q12959	DLG1	P24941	CDK2	T115	D114N	114	Missense	proximal	-1	no	14.720	13.891	EPSD	COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	Q12959	DLG1	P24941	CDK2	S122	I121V	121	Missense	proximal	-1	no	11.137	11.111	EPSD	COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	Q12959	DLG1	P24941	CDK2	S158	I160V	160	Missense	proximal	2	no	14.845	14.991	EPSD;PhosphoSitePlus	COSMIC;CCLE	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	Q12959	DLG1	P24941	CDK2	T209	T209A	209	Missense	central	0	yes	16.030	0.000	EPSD	COSMIC	8.148	Loss
CMGC_CDK_CDK2_CDK2_ST	Q12959	DLG1	P24941	CDK2	S432	Q439L	439	Missense	distal	7	no	11.350	11.535	EPSD	COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	Q12959	DLG1	P24941	CDK2	T440	Q439L	439	Missense	proximal	-1	no	11.846	11.975	EPSD	COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	Q12959	DLG1	P24941	CDK2	S443	Q439L	439	Missense	distal	-4	no	15.997	16.157	PhosphoSitePlus;EPSD	COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	Q12959	DLG1	P24941	CDK2	S448	A453V	453	Missense	distal	5	no	13.899	13.856	EPSD	COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	Q12959	DLG1	P24941	CDK2	S448	V454I	454	Missense	distal	6	no	13.899	13.901	EPSD	COSMIC;GDSC;CCLE	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	Q12959	DLG1	P24941	CDK2	S448	L455I	455	Missense	distal	7	no	13.899	13.926	EPSD	COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	Q12959	DLG1	P24941	CDK2	T630	T630K	630	Missense	central	0	yes	13.267	0.000	EPSD	COSMIC	8.148	Loss
CMGC_CDK_CDK2_CDK2_ST	Q12959	DLG1	P24941	CDK2	T630	T630I	630	Missense	central	0	yes	13.267	0.000	EPSD	COSMIC	8.148	Loss
CMGC_CDK_CDK2_CDK2_ST	Q12959	DLG1	P24941	CDK2	T630	G633C	633	Missense	distal	3	no	13.267	8.722	EPSD	COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	Q12959	DLG1	P24941	CDK2	T630	G633V	633	Missense	distal	3	no	13.267	13.976	EPSD	COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	Q12959	DLG1	P24941	CDK2	T630	D636N	636	Missense	distal	6	no	13.267	13.286	EPSD	COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	Q86T82	USP37	P24941	CDK2	T191	S195L	195	Missense	distal	4	no	14.525	14.623	EPSD	COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	Q86T82	USP37	P24941	CDK2	T191	P184S	184	Missense	distal	-7	no	14.525	14.345	EPSD	COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	Q86T82	USP37	P24941	CDK2	T295	N290D	290	Missense	distal	-5	no	11.264	11.302	EPSD	COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	Q86T82	USP37	P24941	CDK2	T295	R288S	288	Missense	distal	-7	no	11.264	10.740	EPSD	COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	Q86T82	USP37	P24941	CDK2	T295	V291I	291	Missense	distal	-4	no	11.264	11.161	EPSD	COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	Q86T82	USP37	P24941	CDK2	S422	R420K	420	Missense	proximal	-2	no	7.697	8.419	EPSD	COSMIC;GDSC	8.148	Gain
CMGC_CDK_CDK2_CDK2_ST	Q86T82	USP37	P24941	CDK2	S462	R469T	469	Missense	distal	7	no	12.626	11.832	EPSD	COSMIC;GDSC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	Q86XL3	ANKLE2	P24941	CDK2	T47	P48A	48	Missense	proximal	1	no	13.097	-1.306	EPSD	COSMIC	8.148	Loss
CMGC_CDK_CDK2_CDK2_ST	Q86XL3	ANKLE2	P24941	CDK2	T47	V49A	49	Missense	proximal	2	no	13.097	12.999	EPSD	COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	Q86XL3	ANKLE2	P24941	CDK2	S259	Y256C	256	Missense	distal	-3	no	16.639	16.628	EPSD	COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	Q86XL3	ANKLE2	P24941	CDK2	S259	I253S	253	Missense	distal	-6	no	16.639	16.636	EPSD	COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	Q86XL3	ANKLE2	P24941	CDK2	T448	E450K	450	Missense	proximal	2	no	10.206	9.968	EPSD	COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	Q86XL3	ANKLE2	P24941	CDK2	S488	G492R	492	Missense	distal	4	no	13.370	13.369	EPSD	COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	Q86XL3	ANKLE2	P24941	CDK2	S488	E493V	493	Missense	distal	5	no	13.370	13.258	EPSD	COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	Q86XL3	ANKLE2	P24941	CDK2	S496	G492R	492	Missense	distal	-4	no	16.120	16.195	EPSD	COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	Q86XL3	ANKLE2	P24941	CDK2	S496	A501T	501	Missense	distal	5	no	16.120	16.084	EPSD	COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	Q86XL3	ANKLE2	P24941	CDK2	S496	E493V	493	Missense	distal	-3	no	16.120	16.088	EPSD	COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	Q86XL3	ANKLE2	P24941	CDK2	S496	A501V	501	Missense	distal	5	no	16.120	16.077	EPSD	COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	Q86XL3	ANKLE2	P24941	CDK2	S512	V506I	506	Missense	distal	-6	no	12.853	12.854	EPSD	COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	Q86XL3	ANKLE2	P24941	CDK2	S512	R508G	508	Missense	distal	-4	no	12.853	12.778	EPSD	COSMIC;GDSC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	Q86XL3	ANKLE2	P24941	CDK2	S512	P516Q	516	Missense	distal	4	no	12.853	12.914	EPSD	COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	Q86XL3	ANKLE2	P24941	CDK2	S528	A524T	524	Missense	distal	-4	no	18.476	18.702	PhosphoSitePlus	COSMIC;GDSC;CCLE	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	Q86XL3	ANKLE2	P24941	CDK2	T541	E545D	545	Missense	distal	4	no	15.373	15.291	EPSD	COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	Q86XL3	ANKLE2	P24941	CDK2	S556	K555N	555	Missense	proximal	-1	no	8.360	8.386	EPSD	COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	Q86XL3	ANKLE2	P24941	CDK2	S556	F549L	549	Missense	distal	-7	no	8.360	7.994	EPSD	COSMIC	8.148	Loss
CMGC_CDK_CDK2_CDK2_ST	Q86XL3	ANKLE2	P24941	CDK2	S647	E650K	650	Missense	distal	3	no	7.512	9.598	EPSD	COSMIC	8.148	Gain
CMGC_CDK_CDK2_CDK2_ST	Q86XL3	ANKLE2	P24941	CDK2	S662	S662G	662	Missense	central	0	yes	12.775	0.000	EPSD	COSMIC	8.148	Loss
CMGC_CDK_CDK2_CDK2_ST	Q86XL3	ANKLE2	P24941	CDK2	S662	G667S	667	Missense	distal	5	no	12.775	12.548	EPSD	COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	Q86XL3	ANKLE2	P24941	CDK2	S662	P663S	663	Missense	proximal	1	no	12.775	1.509	EPSD	COSMIC	8.148	Loss
CMGC_CDK_CDK2_CDK2_ST	Q86XL3	ANKLE2	P24941	CDK2	T751	S749C	749	Missense	proximal	-2	no	13.354	12.944	EPSD	COSMIC;GDSC;CCLE	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	Q86XL3	ANKLE2	P24941	CDK2	S778	S778C	778	Missense	central	0	yes	11.702	0.000	EPSD	COSMIC	8.148	Loss
CMGC_CDK_CDK2_CDK2_ST	Q86XL3	ANKLE2	P24941	CDK2	S778	P779L	779	Missense	proximal	1	no	11.702	1.881	EPSD	COSMIC	8.148	Loss
CMGC_CDK_CDK2_CDK2_ST	Q86XL3	ANKLE2	P24941	CDK2	S778	Q782K	782	Missense	distal	4	no	11.702	12.042	EPSD	COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	Q86XL3	ANKLE2	P24941	CDK2	S804	P805A	805	Missense	proximal	1	no	13.905	-0.498	EPSD	COSMIC;GDSC;CCLE	8.148	Loss
CMGC_CDK_CDK2_CDK2_ST	Q86XL3	ANKLE2	P24941	CDK2	S807	P805A	805	Missense	proximal	-2	no	13.820	13.836	EPSD	COSMIC;GDSC;CCLE	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	Q86XL3	ANKLE2	P24941	CDK2	S896	G891A	891	Missense	distal	-5	no	17.435	17.380	EPSD	COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	Q86XL3	ANKLE2	P24941	CDK2	S896	V902M	902	Missense	distal	6	no	17.435	17.418	EPSD	COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	Q86XL3	ANKLE2	P24941	CDK2	S896	P892S	892	Missense	distal	-4	no	17.435	17.790	EPSD	COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	Q86XL3	ANKLE2	P24941	CDK2	S919	L926I	926	Missense	distal	7	no	15.932	15.958	EPSD	COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	Q86XL3	ANKLE2	P24941	CDK2	S924	R931C	931	Missense	distal	7	no	9.524	9.676	EPSD	COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	Q86XL3	ANKLE2	P24941	CDK2	S924	A930V	930	Missense	distal	6	no	9.524	9.527	EPSD	COSMIC;CCLE	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	Q86XL3	ANKLE2	P24941	CDK2	S924	L926I	926	Missense	proximal	2	no	9.524	9.608	EPSD	COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	Q9H3P2	NELFA	P24941	CDK2	T157	G154R	154	Missense	distal	-3	no	13.815	13.900	PhosphoSitePlus	COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	Q9H3P2	NELFA	P24941	CDK2	T157	A153V	153	Missense	distal	-4	no	13.815	13.826	PhosphoSitePlus	COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	Q9H3P2	NELFA	P24941	CDK2	T157	A153T	153	Missense	distal	-4	no	13.815	14.040	PhosphoSitePlus	COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	Q9H3P2	NELFA	P24941	CDK2	T157	P159L	159	Missense	proximal	2	no	13.815	13.708	PhosphoSitePlus	COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	Q9H3P2	NELFA	P24941	CDK2	T212	R206W	206	Missense	distal	-6	no	13.200	13.206	EPSD	COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	Q9H3P2	NELFA	P24941	CDK2	T212	T212A	212	Missense	central	0	yes	13.200	0.000	EPSD	COSMIC	8.148	Loss
CMGC_CDK_CDK2_CDK2_ST	Q9H3P2	NELFA	P24941	CDK2	T212	R206Q	206	Missense	distal	-6	no	13.200	13.201	EPSD	COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	Q9H3P2	NELFA	P24941	CDK2	T212	P218L	218	Missense	distal	6	no	13.200	13.201	EPSD	COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	Q9H3P2	NELFA	P24941	CDK2	S225	P229L	229	Missense	distal	4	no	13.673	13.785	EPSD	COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	Q9H3P2	NELFA	P24941	CDK2	S225	A228V	228	Missense	distal	3	no	13.673	14.793	EPSD	COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	Q9H3P2	NELFA	P24941	CDK2	S225	A221V	221	Missense	distal	-4	no	13.673	13.684	EPSD	COSMIC;CCLE	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	Q9H3P2	NELFA	P24941	CDK2	S225	Q220H	220	Missense	distal	-5	no	13.673	13.720	EPSD	COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	Q9H3P2	NELFA	P24941	CDK2	S225	P218L	218	Missense	distal	-7	no	13.673	13.679	EPSD	COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	Q9H3P2	NELFA	P24941	CDK2	S233	P229L	229	Missense	distal	-4	no	13.090	13.032	EPSD	COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	Q9H3P2	NELFA	P24941	CDK2	S233	A228V	228	Missense	distal	-5	no	13.090	13.096	EPSD	COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	Q9H3P2	NELFA	P24941	CDK2	S233	P234L	234	Missense	proximal	1	no	13.090	3.269	EPSD	COSMIC	8.148	Loss
CMGC_CDK_CDK2_CDK2_ST	Q9H3P2	NELFA	P24941	CDK2	S233	T239A	239	Missense	distal	6	no	13.090	13.078	EPSD	COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	Q9H3P2	NELFA	P24941	CDK2	T239	P234L	234	Missense	distal	-5	no	14.237	14.249	EPSD	COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	Q9H3P2	NELFA	P24941	CDK2	T239	T246M	246	Missense	distal	7	no	14.237	15.086	EPSD	COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	Q9H3P2	NELFA	P24941	CDK2	T239	T239A	239	Missense	central	0	yes	14.237	0.000	EPSD	COSMIC	8.148	Loss
CMGC_CDK_CDK2_CDK2_ST	Q9H3P2	NELFA	P24941	CDK2	T239	P242L	242	Missense	distal	3	no	14.237	13.854	EPSD	COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	Q9H3P2	NELFA	P24941	CDK2	T246	T239A	239	Missense	distal	-7	no	8.110	8.277	EPSD	COSMIC	8.148	Gain
CMGC_CDK_CDK2_CDK2_ST	Q9H3P2	NELFA	P24941	CDK2	T297	T291M	291	Missense	distal	-6	no	11.544	11.552	EPSD	COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	Q9H3P2	NELFA	P24941	CDK2	T297	G303S	303	Missense	distal	6	no	11.544	11.557	EPSD	COSMIC;CCLE	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	Q9H3P2	NELFA	P24941	CDK2	T328	S321C	321	Missense	distal	-7	no	12.953	13.404	EPSD	COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	Q9H3P2	NELFA	P24941	CDK2	T328	T328M	328	Missense	central	0	yes	12.953	0.000	EPSD	COSMIC	8.148	Loss
CMGC_CDK_CDK2_CDK2_ST	Q9H3P2	NELFA	P24941	CDK2	T328	A334T	334	Missense	distal	6	no	12.953	12.965	EPSD	COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	Q9H3P2	NELFA	P24941	CDK2	T328	A334G	334	Missense	distal	6	no	12.953	12.946	EPSD	COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	Q9H3P2	NELFA	P24941	CDK2	T343	S340R	340	Missense	distal	-3	no	13.929	14.022	EPSD	COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	Q9H3P2	NELFA	P24941	CDK2	T343	A346S	346	Missense	distal	3	no	13.929	14.475	EPSD	COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	Q9H3P2	NELFA	P24941	CDK2	S363	A361T	361	Missense	proximal	-2	no	12.649	12.599	EPSD	COSMIC;CCLE	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	Q9H3P2	NELFA	P24941	CDK2	S363	T365M	365	Missense	proximal	2	no	12.649	13.037	EPSD	COSMIC;CCLE	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	Q9H3P2	NELFA	P24941	CDK2	T385	T387M	387	Missense	proximal	2	no	11.560	11.948	EPSD	COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	Q9H3P2	NELFA	P24941	CDK2	T385	A389V	389	Missense	distal	4	no	11.560	11.747	EPSD	COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	Q9H3P2	NELFA	P24941	CDK2	T385	A390T	390	Missense	distal	5	no	11.560	11.524	EPSD	COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	Q9H3P2	NELFA	P24941	CDK2	T385	L381M	381	Missense	distal	-4	no	11.560	10.870	EPSD	COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	Q9H3P2	NELFA	P24941	CDK2	T387	T387M	387	Missense	central	0	yes	12.370	0.000	EPSD	COSMIC	8.148	Loss
CMGC_CDK_CDK2_CDK2_ST	Q9H3P2	NELFA	P24941	CDK2	T387	A389V	389	Missense	proximal	2	no	12.370	12.468	EPSD	COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	Q9H3P2	NELFA	P24941	CDK2	T387	A390T	390	Missense	distal	3	no	12.370	12.768	EPSD	COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	Q9H3P2	NELFA	P24941	CDK2	T387	L381M	381	Missense	distal	-6	no	12.370	12.377	EPSD	COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	Q9H3P2	NELFA	P24941	CDK2	S393	T387M	387	Missense	distal	-6	no	13.925	13.932	EPSD	COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	Q9H3P2	NELFA	P24941	CDK2	S393	P400T	400	Missense	distal	7	no	13.925	13.621	EPSD	COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	Q9H3P2	NELFA	P24941	CDK2	S393	A389V	389	Missense	distal	-4	no	13.925	13.935	EPSD	COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	Q9H3P2	NELFA	P24941	CDK2	S393	P400S	400	Missense	distal	7	no	13.925	13.773	EPSD	COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	Q9H3P2	NELFA	P24941	CDK2	S393	A390T	390	Missense	distal	-3	no	13.925	13.943	EPSD	COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	Q9H3P2	NELFA	P24941	CDK2	T396	P400T	400	Missense	distal	4	no	12.911	13.194	EPSD	COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	Q9H3P2	NELFA	P24941	CDK2	T396	A389V	389	Missense	distal	-7	no	12.911	12.766	EPSD	COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	Q9H3P2	NELFA	P24941	CDK2	T396	P400S	400	Missense	distal	4	no	12.911	12.924	EPSD	COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	Q9H3P2	NELFA	P24941	CDK2	T396	P401L	401	Missense	distal	5	no	12.911	12.951	EPSD	COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	Q9H3P2	NELFA	P24941	CDK2	T396	A390T	390	Missense	distal	-6	no	12.911	12.912	EPSD	COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	Q9H3P2	NELFA	P24941	CDK2	T399	T406N	406	Missense	distal	7	no	13.055	13.266	EPSD	COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	Q9H3P2	NELFA	P24941	CDK2	T399	P400T	400	Missense	proximal	1	no	13.055	3.098	EPSD	COSMIC	8.148	Loss
CMGC_CDK_CDK2_CDK2_ST	Q9H3P2	NELFA	P24941	CDK2	T399	P400S	400	Missense	proximal	1	no	13.055	1.789	EPSD	COSMIC	8.148	Loss
CMGC_CDK_CDK2_CDK2_ST	Q9H3P2	NELFA	P24941	CDK2	T399	P401L	401	Missense	proximal	2	no	13.055	12.948	EPSD	COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	Q9H3P2	NELFA	P24941	CDK2	T409	P411T	411	Missense	proximal	2	no	13.577	13.399	EPSD	COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	Q9H3P2	NELFA	P24941	CDK2	T409	P411S	411	Missense	proximal	2	no	13.577	13.643	EPSD	COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	Q9H3P2	NELFA	P24941	CDK2	T409	T406N	406	Missense	distal	-3	no	13.577	13.637	EPSD	COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	Q9H3P2	NELFA	P24941	CDK2	T409	Q408H	408	Missense	proximal	-1	no	13.577	14.004	EPSD	COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	Q9H3P2	NELFA	P24941	CDK2	T409	P410L	410	Missense	proximal	1	no	13.577	3.756	EPSD	COSMIC	8.148	Loss
CMGC_CDK_CDK2_CDK2_ST	Q9H3P2	NELFA	P24941	CDK2	T409	P411L	411	Missense	proximal	2	no	13.577	13.470	EPSD	COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	Q9UKY1	ZHX1	P24941	CDK2	T9	T8A	8	Missense	proximal	-1	no	11.035	11.028	EPSD	COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	Q9UKY1	ZHX1	P24941	CDK2	T9	A15T	15	Missense	distal	6	no	11.035	11.047	EPSD	COSMIC;GDSC;CCLE	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	Q9UKY1	ZHX1	P24941	CDK2	T36	P33L	33	Missense	distal	-3	no	15.400	15.329	EPSD	COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	Q9UKY1	ZHX1	P24941	CDK2	T36	G31V	31	Missense	distal	-5	no	15.400	15.352	EPSD	COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	Q9UKY1	ZHX1	P24941	CDK2	T252	G259R	259	Missense	distal	7	no	11.121	10.941	EPSD	COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	Q9UKY1	ZHX1	P24941	CDK2	T252	V251L	251	Missense	proximal	-1	no	11.121	10.985	EPSD	COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	Q9UKY1	ZHX1	P24941	CDK2	S549	T547M	547	Missense	proximal	-2	no	12.037	9.986	EPSD	COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	Q9UKY1	ZHX1	P24941	CDK2	T568	K571T	571	Missense	distal	3	no	16.490	13.668	PhosphoSitePlus	COSMIC;GDSC;CCLE	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	Q9UKY1	ZHX1	P24941	CDK2	T668	P669H	669	Missense	proximal	1	no	12.713	5.955	EPSD	COSMIC	8.148	Loss
CMGC_CDK_CDK2_CDK2_ST	Q9UKY1	ZHX1	P24941	CDK2	S774	D770G	770	Missense	distal	-4	no	8.270	7.425	EPSD	COSMIC;GDSC;CCLE	8.148	Loss
CMGC_CDK_CDK2_CDK2_ST	P08621	SNRNP70	P24941	CDK2	S226	R233L	233	Missense	distal	7	no	15.254	14.795	PhosphoSitePlus	COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	P08621	SNRNP70	P24941	CDK2	S226	E221D	221	Missense	distal	-5	no	15.254	15.274	PhosphoSitePlus	COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	P08621	SNRNP70	P24941	CDK2	S357	R354Q	354	Missense	distal	-3	no	9.664	9.533	EPSD	COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	P08621	SNRNP70	P24941	CDK2	S357	R362H	362	Missense	distal	5	no	9.664	9.635	EPSD	COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	P08621	SNRNP70	P24941	CDK2	S357	R362C	362	Missense	distal	5	no	9.664	9.791	EPSD	COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	P08621	SNRNP70	P24941	CDK2	S357	R359W	359	Missense	proximal	2	no	9.664	9.761	EPSD	COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	Q14676	MDC1	P24941	CDK2	S108	P109A	109	Missense	proximal	1	no	13.497	-0.907	EPSD	COSMIC	8.148	Loss
CMGC_CDK_CDK2_CDK2_ST	Q14676	MDC1	P24941	CDK2	S108	H113P	113	Missense	distal	5	no	13.497	13.419	EPSD	COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	Q14676	MDC1	P24941	CDK2	S108	P103L	103	Missense	distal	-5	no	13.497	13.508	EPSD	COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	Q14676	MDC1	P24941	CDK2	S108	P104S	104	Missense	distal	-4	no	13.497	13.851	EPSD	COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	Q14676	MDC1	P24941	CDK2	S108	P104L	104	Missense	distal	-4	no	13.497	13.438	EPSD	COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	Q14676	MDC1	P24941	CDK2	S112	H113P	113	Missense	proximal	1	no	7.515	14.273	EPSD	COSMIC	8.148	Gain
CMGC_CDK_CDK2_CDK2_ST	Q14676	MDC1	P24941	CDK2	T150	E148K	148	Missense	proximal	-2	no	14.139	14.739	EPSD	COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	Q14676	MDC1	P24941	CDK2	T150	E149A	149	Missense	proximal	-1	no	14.139	13.083	EPSD	COSMIC;GDSC;CCLE	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	Q14676	MDC1	P24941	CDK2	S202	G200E	200	Missense	proximal	-2	no	13.551	13.178	EPSD	COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	Q14676	MDC1	P24941	CDK2	T341	V343I	343	Missense	proximal	2	no	14.347	14.201	EPSD;PhosphoSitePlus	COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	Q14676	MDC1	P24941	CDK2	T341	P346A	346	Missense	distal	5	no	14.347	14.357	EPSD;PhosphoSitePlus	COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	Q14676	MDC1	P24941	CDK2	T341	P342S	342	Missense	proximal	1	no	14.347	3.081	EPSD;PhosphoSitePlus	COSMIC	8.148	Loss
CMGC_CDK_CDK2_CDK2_ST	Q14676	MDC1	P24941	CDK2	S505	H509P	509	Missense	distal	4	no	12.135	12.372	EPSD	COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	Q14676	MDC1	P24941	CDK2	S505	D502Y	502	Missense	distal	-3	no	12.135	12.184	EPSD	COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	Q14676	MDC1	P24941	CDK2	T579	E582K	582	Missense	distal	3	no	6.895	8.981	EPSD	COSMIC	8.148	Gain
CMGC_CDK_CDK2_CDK2_ST	Q14676	MDC1	P24941	CDK2	T725	L730P	730	Missense	distal	5	no	9.897	9.857	EPSD	COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	Q14676	MDC1	P24941	CDK2	T725	P726A	726	Missense	proximal	1	no	9.897	-4.507	EPSD	COSMIC	8.148	Loss
CMGC_CDK_CDK2_CDK2_ST	Q14676	MDC1	P24941	CDK2	T770	E773K	773	Missense	distal	3	no	7.941	10.026	EPSD	COSMIC	8.148	Gain
CMGC_CDK_CDK2_CDK2_ST	Q14676	MDC1	P24941	CDK2	T770	S763F	763	Missense	distal	-7	no	7.941	8.492	EPSD	COSMIC;GDSC;CCLE	8.148	Gain
CMGC_CDK_CDK2_CDK2_ST	Q14676	MDC1	P24941	CDK2	S780	A784S	784	Missense	distal	4	no	15.760	15.734	EPSD	COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	Q14676	MDC1	P24941	CDK2	S780	E773K	773	Missense	distal	-7	no	15.760	15.623	EPSD	COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	Q14676	MDC1	P24941	CDK2	S793	H796N	796	Missense	distal	3	no	17.286	15.701	EPSD	COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	Q14676	MDC1	P24941	CDK2	T847	E850K	850	Missense	distal	3	no	6.615	8.700	EPSD	COSMIC	8.148	Gain
CMGC_CDK_CDK2_CDK2_ST	Q14676	MDC1	P24941	CDK2	S882	G878V	878	Missense	distal	-4	no	14.584	14.854	EPSD	COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	Q14676	MDC1	P24941	CDK2	S882	E888K	888	Missense	distal	6	no	14.584	14.595	EPSD	COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	Q14676	MDC1	P24941	CDK2	S964	P969R	969	Missense	distal	5	no	12.779	12.885	EPSD	COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	Q14676	MDC1	P24941	CDK2	S964	P967L	967	Missense	distal	3	no	12.779	12.395	EPSD	COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	Q14676	MDC1	P24941	CDK2	S964	P969A	969	Missense	distal	5	no	12.779	12.789	EPSD	COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	Q14676	MDC1	P24941	CDK2	T966	P969R	969	Missense	distal	3	no	10.668	12.386	EPSD	COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	Q14676	MDC1	P24941	CDK2	T966	P967L	967	Missense	proximal	1	no	10.668	0.847	EPSD	COSMIC	8.148	Loss
CMGC_CDK_CDK2_CDK2_ST	Q14676	MDC1	P24941	CDK2	T966	P969A	969	Missense	distal	3	no	10.668	10.156	EPSD	COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	Q14676	MDC1	P24941	CDK2	S990	P983S	983	Missense	distal	-7	no	10.018	9.838	EPSD	COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	Q14676	MDC1	P24941	CDK2	S990	S986F	986	Missense	distal	-4	no	10.018	9.056	EPSD	COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	Q14676	MDC1	P24941	CDK2	S990	P996S	996	Missense	distal	6	no	10.018	10.019	EPSD	COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	Q14676	MDC1	P24941	CDK2	S990	P985L	985	Missense	distal	-5	no	10.018	10.030	EPSD	COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	Q14676	MDC1	P24941	CDK2	S990	S995F	995	Missense	distal	5	no	10.018	10.337	EPSD	COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	Q14676	MDC1	P24941	CDK2	S995	P996S	996	Missense	proximal	1	no	12.126	0.861	EPSD	COSMIC	8.148	Loss
CMGC_CDK_CDK2_CDK2_ST	Q14676	MDC1	P24941	CDK2	S995	S995F	995	Missense	central	0	yes	12.126	0.000	EPSD	COSMIC	8.148	Loss
CMGC_CDK_CDK2_CDK2_ST	Q14676	MDC1	P24941	CDK2	S998	P996S	996	Missense	proximal	-2	no	17.115	16.463	EPSD	COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	Q14676	MDC1	P24941	CDK2	S998	S995F	995	Missense	distal	-3	no	17.115	17.206	EPSD	COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	Q14676	MDC1	P24941	CDK2	S1033	D1030Y	1030	Missense	distal	-3	no	10.643	10.693	EPSD	COSMIC;GDSC;CCLE	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	Q14676	MDC1	P24941	CDK2	S1033	G1029D	1029	Missense	distal	-4	no	10.643	11.488	EPSD	COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	Q14676	MDC1	P24941	CDK2	S1068	I1074M	1074	Missense	distal	6	no	13.716	13.697	EPSD;PhosphoSitePlus	COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	Q14676	MDC1	P24941	CDK2	S1068	L1070V	1070	Missense	proximal	2	no	13.716	13.945	EPSD;PhosphoSitePlus	COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	Q14676	MDC1	P24941	CDK2	S1068	P1064L	1064	Missense	distal	-4	no	13.716	13.658	EPSD;PhosphoSitePlus	COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	Q14676	MDC1	P24941	CDK2	S1068	S1073F	1073	Missense	distal	5	no	13.716	14.034	EPSD;PhosphoSitePlus	COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	Q14676	MDC1	P24941	CDK2	S1068	P1063H	1063	Missense	distal	-5	no	13.716	13.763	EPSD;PhosphoSitePlus	COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	Q14676	MDC1	P24941	CDK2	T1116	K1111T	1111	Missense	distal	-5	no	13.217	13.213	EPSD	COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	Q14676	MDC1	P24941	CDK2	T1116	R1110L	1110	Missense	distal	-6	no	13.217	13.215	EPSD	COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	Q14676	MDC1	P24941	CDK2	T1116	A1123P	1123	Missense	distal	7	no	13.217	12.833	EPSD	COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	Q14676	MDC1	P24941	CDK2	T1116	S1122C	1122	Missense	distal	6	no	13.217	13.202	EPSD	COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	Q14676	MDC1	P24941	CDK2	T1116	P1119R	1119	Missense	distal	3	no	13.217	14.936	EPSD	COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	Q14676	MDC1	P24941	CDK2	T1116	A1120S	1120	Missense	distal	4	no	13.217	13.191	EPSD	COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	Q14676	MDC1	P24941	CDK2	T1116	R1114K	1114	Missense	proximal	-2	no	13.217	13.939	EPSD	COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	Q14676	MDC1	P24941	CDK2	T1116	P1119S	1119	Missense	distal	3	no	13.217	13.251	EPSD	COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	Q14676	MDC1	P24941	CDK2	S1122	A1123P	1123	Missense	proximal	1	no	-0.800	13.604	EPSD	COSMIC	8.148	Gain
CMGC_CDK_CDK2_CDK2_ST	Q14676	MDC1	P24941	CDK2	T1138	T1142A	1142	Missense	distal	4	no	13.128	12.886	EPSD	COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	Q14676	MDC1	P24941	CDK2	T1138	A1145T	1145	Missense	distal	7	no	13.128	12.440	EPSD	COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	Q14676	MDC1	P24941	CDK2	T1157	V1155L	1155	Missense	proximal	-2	no	11.865	12.291	EPSD	COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	Q14676	MDC1	P24941	CDK2	T1157	P1160L	1160	Missense	distal	3	no	11.865	11.482	EPSD	COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	Q14676	MDC1	P24941	CDK2	T1179	S1180P	1180	Missense	proximal	1	no	1.453	12.719	EPSD	COSMIC	8.148	Gain
CMGC_CDK_CDK2_CDK2_ST	Q14676	MDC1	P24941	CDK2	T1198	S1194F	1194	Missense	distal	-4	no	12.162	11.200	EPSD	COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	Q14676	MDC1	P24941	CDK2	T1198	T1198I	1198	Missense	central	0	yes	12.162	0.000	EPSD	COSMIC	8.148	Loss
CMGC_CDK_CDK2_CDK2_ST	Q14676	MDC1	P24941	CDK2	T1198	V1196I	1196	Missense	proximal	-2	no	12.162	12.657	EPSD	COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	Q14676	MDC1	P24941	CDK2	T1198	P1204S	1204	Missense	distal	6	no	12.162	12.163	EPSD	COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	Q14676	MDC1	P24941	CDK2	T1254	S1255P	1255	Missense	proximal	1	no	0.018	11.284	EPSD	COSMIC	8.148	Gain
CMGC_CDK_CDK2_CDK2_ST	Q14676	MDC1	P24941	CDK2	T1280	P1283T	1283	Missense	distal	3	no	12.563	12.449	EPSD	COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	Q14676	MDC1	P24941	CDK2	T1280	N1274S	1274	Missense	distal	-6	no	12.563	12.562	EPSD	COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	Q14676	MDC1	P24941	CDK2	T1280	S1277F	1277	Missense	distal	-3	no	12.563	12.654	EPSD	COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	Q14676	MDC1	P24941	CDK2	T1302	R1308W	1308	Missense	distal	6	no	12.215	12.207	EPSD	COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	Q14676	MDC1	P24941	CDK2	T1302	T1302N	1302	Missense	central	0	yes	12.215	0.000	EPSD	COSMIC	8.148	Loss
CMGC_CDK_CDK2_CDK2_ST	Q14676	MDC1	P24941	CDK2	T1302	P1300L	1300	Missense	proximal	-2	no	12.215	11.990	EPSD	COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	Q14676	MDC1	P24941	CDK2	T1321	S1318F	1318	Missense	distal	-3	no	11.941	12.033	EPSD	COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	Q14676	MDC1	P24941	CDK2	T1321	T1324P	1324	Missense	distal	3	no	11.941	12.056	EPSD	COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	Q14676	MDC1	P24941	CDK2	T1321	M1316V	1316	Missense	distal	-5	no	11.941	11.865	EPSD	COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	Q14676	MDC1	P24941	CDK2	T1321	S1318A	1318	Missense	distal	-3	no	11.941	11.788	EPSD	COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	Q14676	MDC1	P24941	CDK2	T1321	P1327R	1327	Missense	distal	6	no	11.941	11.925	EPSD	COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	Q14676	MDC1	P24941	CDK2	T1321	M1316T	1316	Missense	distal	-5	no	11.941	11.833	EPSD	COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	Q14676	MDC1	P24941	CDK2	S1335	T1336P	1336	Missense	proximal	1	no	3.196	13.153	EPSD	COSMIC	8.148	Gain
CMGC_CDK_CDK2_CDK2_ST	Q14676	MDC1	P24941	CDK2	T1343	R1349Q	1349	Missense	distal	6	no	12.135	12.157	EPSD	COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	Q14676	MDC1	P24941	CDK2	T1343	T1336P	1336	Missense	distal	-7	no	12.135	12.138	EPSD	COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	Q14676	MDC1	P24941	CDK2	T1343	T1343I	1343	Missense	central	0	yes	12.135	0.000	EPSD	COSMIC	8.148	Loss
CMGC_CDK_CDK2_CDK2_ST	Q14676	MDC1	P24941	CDK2	T1343	R1349L	1349	Missense	distal	6	no	12.135	12.153	EPSD	COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	Q14676	MDC1	P24941	CDK2	T1343	Q1340R	1340	Missense	distal	-3	no	12.135	12.266	EPSD	COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	Q14676	MDC1	P24941	CDK2	T1384	T1384P	1384	Missense	central	0	yes	13.621	0.000	EPSD	COSMIC	8.148	Loss
CMGC_CDK_CDK2_CDK2_ST	Q14676	MDC1	P24941	CDK2	T1384	T1384I	1384	Missense	central	0	yes	13.621	0.000	EPSD	COSMIC	8.148	Loss
CMGC_CDK_CDK2_CDK2_ST	Q14676	MDC1	P24941	CDK2	T1384	E1380D	1380	Missense	distal	-4	no	13.621	13.918	EPSD	COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	Q14676	MDC1	P24941	CDK2	T1403	P1409L	1409	Missense	distal	6	no	12.170	12.171	EPSD	COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	Q14676	MDC1	P24941	CDK2	T1403	G1401C	1401	Missense	proximal	-2	no	12.170	11.851	EPSD	COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	Q14676	MDC1	P24941	CDK2	T1403	R1398I	1398	Missense	distal	-5	no	12.170	12.162	EPSD	COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	Q14676	MDC1	P24941	CDK2	T1425	P1428S	1428	Missense	distal	3	no	13.449	13.484	EPSD	COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	Q14676	MDC1	P24941	CDK2	T1425	Q1431E	1431	Missense	distal	6	no	13.449	13.441	EPSD	COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	Q14676	MDC1	P24941	CDK2	T1425	P1428H	1428	Missense	distal	3	no	13.449	14.472	EPSD	COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	Q14676	MDC1	P24941	CDK2	T1444	R1439K	1439	Missense	distal	-5	no	12.119	12.074	EPSD	COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	Q14676	MDC1	P24941	CDK2	S1458	T1459P	1459	Missense	proximal	1	no	3.522	13.479	EPSD	COSMIC	8.148	Gain
CMGC_CDK_CDK2_CDK2_ST	Q14676	MDC1	P24941	CDK2	T1466	T1470A	1470	Missense	distal	4	no	13.903	13.660	EPSD	COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	Q14676	MDC1	P24941	CDK2	T1466	T1459P	1459	Missense	distal	-7	no	13.903	13.906	EPSD	COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	Q14676	MDC1	P24941	CDK2	T1466	Q1472K	1472	Missense	distal	6	no	13.903	13.906	EPSD	COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	Q14676	MDC1	P24941	CDK2	T1466	S1471F	1471	Missense	distal	5	no	13.903	14.222	EPSD	COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	Q14676	MDC1	P24941	CDK2	T1466	P1469S	1469	Missense	distal	3	no	13.903	13.937	EPSD	COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	Q14676	MDC1	P24941	CDK2	T1466	V1465L	1465	Missense	proximal	-1	no	13.903	13.767	EPSD	COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	Q14676	MDC1	P24941	CDK2	T1485	T1488R	1488	Missense	distal	3	no	11.926	13.758	EPSD	COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	Q14676	MDC1	P24941	CDK2	T1485	V1483I	1483	Missense	proximal	-2	no	11.926	12.421	EPSD	COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	Q14676	MDC1	P24941	CDK2	T1485	T1488P	1488	Missense	distal	3	no	11.926	12.040	EPSD	COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	Q14676	MDC1	P24941	CDK2	T1485	D1479H	1479	Missense	distal	-6	no	11.926	11.931	EPSD	COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	Q14676	MDC1	P24941	CDK2	T1485	P1486T	1486	Missense	proximal	1	no	11.926	1.968	EPSD	COSMIC	8.148	Loss
CMGC_CDK_CDK2_CDK2_ST	Q14676	MDC1	P24941	CDK2	T1485	S1481T	1481	Missense	distal	-4	no	11.926	11.738	EPSD	COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	Q14676	MDC1	P24941	CDK2	T1507	S1508P	1508	Missense	proximal	1	no	1.754	13.020	EPSD	COSMIC	8.148	Gain
CMGC_CDK_CDK2_CDK2_ST	Q14676	MDC1	P24941	CDK2	T1526	R1521W	1521	Missense	distal	-5	no	12.329	12.417	EPSD	COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	Q14676	MDC1	P24941	CDK2	T1526	A1533E	1533	Missense	distal	7	no	12.329	11.989	EPSD	COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	Q14676	MDC1	P24941	CDK2	T1548	P1551A	1551	Missense	distal	3	no	13.319	12.807	EPSD	COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	Q14676	MDC1	P24941	CDK2	T1548	R1554Q	1554	Missense	distal	6	no	13.319	13.341	EPSD	COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	Q14676	MDC1	P24941	CDK2	T1548	P1551S	1551	Missense	distal	3	no	13.319	13.353	EPSD	COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	Q14676	MDC1	P24941	CDK2	T1548	T1552S	1552	Missense	distal	4	no	13.319	13.050	EPSD	COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	Q14676	MDC1	P24941	CDK2	T1548	A1555T	1555	Missense	distal	7	no	13.319	12.631	EPSD	COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	Q14676	MDC1	P24941	CDK2	T1567	R1562T	1562	Missense	distal	-5	no	12.663	12.615	EPSD	COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	Q14676	MDC1	P24941	CDK2	T1567	I1574V	1574	Missense	distal	7	no	12.663	12.865	EPSD	COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	Q14676	MDC1	P24941	CDK2	T1567	R1562M	1562	Missense	distal	-5	no	12.663	12.723	EPSD	COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	Q14676	MDC1	P24941	CDK2	T1567	P1573A	1573	Missense	distal	6	no	12.663	12.659	EPSD	COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	Q14676	MDC1	P24941	CDK2	T1589	P1590T	1590	Missense	proximal	1	no	12.947	2.989	EPSD	COSMIC	8.148	Loss
CMGC_CDK_CDK2_CDK2_ST	Q14676	MDC1	P24941	CDK2	T1589	S1594Y	1594	Missense	distal	5	no	12.947	13.121	EPSD	COSMIC;GDSC;CCLE	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	Q14676	MDC1	P24941	CDK2	T1589	P1590L	1590	Missense	proximal	1	no	12.947	3.126	EPSD	COSMIC	8.148	Loss
CMGC_CDK_CDK2_CDK2_ST	Q14676	MDC1	P24941	CDK2	T1589	P1590S	1590	Missense	proximal	1	no	12.947	1.681	EPSD	COSMIC	8.148	Loss
CMGC_CDK_CDK2_CDK2_ST	Q14676	MDC1	P24941	CDK2	T1589	P1592L	1592	Missense	distal	3	no	12.947	12.563	EPSD	COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	Q14676	MDC1	P24941	CDK2	T1608	T1601I	1601	Missense	distal	-7	no	11.373	11.570	EPSD	COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	Q14676	MDC1	P24941	CDK2	T1608	T1615I	1615	Missense	distal	7	no	11.373	11.734	EPSD	COSMIC;GDSC;CCLE	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	Q14676	MDC1	P24941	CDK2	T1608	S1604F	1604	Missense	distal	-4	no	11.373	10.411	EPSD	COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	Q14676	MDC1	P24941	CDK2	T1608	P1609A	1609	Missense	proximal	1	no	11.373	-3.031	EPSD	COSMIC	8.148	Loss
CMGC_CDK_CDK2_CDK2_ST	Q14676	MDC1	P24941	CDK2	T1630	S1635F	1635	Missense	distal	5	no	12.643	12.961	PhosphoSitePlus;EPSD	COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	Q14676	MDC1	P24941	CDK2	T1630	S1624C	1624	Missense	distal	-6	no	12.643	12.649	PhosphoSitePlus;EPSD	COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	Q14676	MDC1	P24941	CDK2	T1630	P1631S	1631	Missense	proximal	1	no	12.643	1.377	PhosphoSitePlus;EPSD	COSMIC	8.148	Loss
CMGC_CDK_CDK2_CDK2_ST	Q14676	MDC1	P24941	CDK2	T1630	P1628S	1628	Missense	proximal	-2	no	12.643	11.992	PhosphoSitePlus;EPSD	COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	Q14676	MDC1	P24941	CDK2	T1649	R1644G	1644	Missense	distal	-5	no	11.947	11.980	EPSD	COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	Q14676	MDC1	P24941	CDK2	T1649	V1653F	1653	Missense	distal	4	no	11.947	11.538	EPSD	COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	Q14676	MDC1	P24941	CDK2	T1649	A1656T	1656	Missense	distal	7	no	11.947	11.259	EPSD	COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	Q14676	MDC1	P24941	CDK2	T1649	R1644S	1644	Missense	distal	-5	no	11.947	11.856	EPSD	COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	Q14676	MDC1	P24941	CDK2	T1664	D1659Y	1659	Missense	distal	-5	no	12.247	12.214	EPSD	COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	Q14676	MDC1	P24941	CDK2	T1664	T1671P	1671	Missense	distal	7	no	12.247	12.551	EPSD	COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	Q14676	MDC1	P24941	CDK2	T1664	P1662S	1662	Missense	proximal	-2	no	12.247	11.596	EPSD	COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	Q14676	MDC1	P24941	CDK2	T1664	L1660I	1660	Missense	distal	-4	no	12.247	12.155	EPSD	COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	Q14676	MDC1	P24941	CDK2	T1664	E1661Q	1661	Missense	distal	-3	no	12.247	12.131	EPSD	COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	Q14676	MDC1	P24941	CDK2	T1664	Q1668L	1668	Missense	distal	4	no	12.247	12.298	EPSD	COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	Q14676	MDC1	P24941	CDK2	T1664	D1667E	1667	Missense	distal	3	no	12.247	14.683	EPSD	COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	Q14676	MDC1	P24941	CDK2	T1671	P1672S	1672	Missense	proximal	1	no	14.663	3.397	EPSD	COSMIC	8.148	Loss
CMGC_CDK_CDK2_CDK2_ST	Q14676	MDC1	P24941	CDK2	T1671	T1671P	1671	Missense	central	0	yes	14.663	0.000	EPSD	COSMIC	8.148	Loss
CMGC_CDK_CDK2_CDK2_ST	Q14676	MDC1	P24941	CDK2	T1671	T1664S	1664	Missense	distal	-7	no	14.663	14.486	EPSD	COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	Q14676	MDC1	P24941	CDK2	T1671	Q1677R	1677	Missense	distal	6	no	14.663	14.641	EPSD	COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	Q14676	MDC1	P24941	CDK2	T1671	Q1668L	1668	Missense	distal	-3	no	14.663	14.534	EPSD	COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	Q14676	MDC1	P24941	CDK2	T1671	D1667E	1667	Missense	distal	-4	no	14.663	14.366	EPSD	COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	Q14676	MDC1	P24941	CDK2	T1697	P1698L	1698	Missense	proximal	1	no	14.653	4.832	EPSD	COSMIC	8.148	Loss
CMGC_CDK_CDK2_CDK2_ST	Q14676	MDC1	P24941	CDK2	T1697	P1693L	1693	Missense	distal	-4	no	14.653	14.594	EPSD	COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	Q14676	MDC1	P24941	CDK2	T1697	R1690K	1690	Missense	distal	-7	no	14.653	14.262	EPSD	COSMIC;GDSC;CCLE	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	Q14676	MDC1	P24941	CDK2	S1702	P1698L	1698	Missense	distal	-4	no	11.919	11.860	EPSD	COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	Q14676	MDC1	P24941	CDK2	S1702	T1705I	1705	Missense	distal	3	no	11.919	11.365	EPSD	COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	Q14676	MDC1	P24941	CDK2	S1702	T1706I	1706	Missense	distal	4	no	11.919	11.607	EPSD	COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	Q14676	MDC1	P24941	CDK2	S1711	I1710M	1710	Missense	proximal	-1	no	13.926	14.993	EPSD	COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	Q14676	MDC1	P24941	CDK2	S1711	T1705I	1705	Missense	distal	-6	no	13.926	13.928	EPSD	COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	Q14676	MDC1	P24941	CDK2	S1711	P1718L	1718	Missense	distal	7	no	13.926	13.956	EPSD	COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	Q14676	MDC1	P24941	CDK2	S1711	T1706I	1706	Missense	distal	-5	no	13.926	13.966	EPSD	COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	Q14676	MDC1	P24941	CDK2	T1800	S1797F	1797	Missense	distal	-3	no	11.916	12.008	EPSD	COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	Q14676	MDC1	P24941	CDK2	T1800	P1801Q	1801	Missense	proximal	1	no	11.916	4.005	EPSD	COSMIC	8.148	Loss
CMGC_CDK_CDK2_CDK2_ST	Q14676	MDC1	P24941	CDK2	T1800	P1801L	1801	Missense	proximal	1	no	11.916	2.095	EPSD	COSMIC;GDSC;CCLE	8.148	Loss
CMGC_CDK_CDK2_CDK2_ST	Q14676	MDC1	P24941	CDK2	T1800	A1794T	1794	Missense	distal	-6	no	11.916	11.917	EPSD	COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	Q14676	MDC1	P24941	CDK2	T1858	R1864T	1864	Missense	distal	6	no	12.923	12.947	EPSD	COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	Q14676	MDC1	P24941	CDK2	T1858	V1857L	1857	Missense	proximal	-1	no	12.923	12.787	EPSD	COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	Q14676	MDC1	P24941	CDK2	T1858	D1855N	1855	Missense	distal	-3	no	12.923	12.879	EPSD	COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	Q14676	MDC1	P24941	CDK2	T1858	K1863N	1863	Missense	distal	5	no	12.923	13.080	EPSD	COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	Q8WXE1	ATRIP	P24941	CDK2	T26	R19L	19	Missense	distal	-7	no	10.946	10.608	EPSD	COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	Q8WXE1	ATRIP	P24941	CDK2	T26	R19Q	19	Missense	distal	-7	no	10.946	10.559	EPSD	COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	Q8WXE1	ATRIP	P24941	CDK2	S224	P218S	218	Missense	distal	-6	no	15.669	15.668	PhosphoSitePlus	COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	Q8WXE1	ATRIP	P24941	CDK2	S224	N228T	228	Missense	distal	4	no	15.669	15.972	PhosphoSitePlus	COSMIC;CCLE	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	Q8WXE1	ATRIP	P24941	CDK2	S239	S246Y	246	Missense	distal	7	no	12.341	12.762	EPSD	COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	P50613	CDK7	P24941	CDK2	T110	S106I	106	Missense	distal	-4	no	13.509	13.003	EPSD	COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	P50613	CDK7	P24941	CDK2	S112	S106I	106	Missense	distal	-6	no	11.467	11.470	EPSD	COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	P50613	CDK7	P24941	CDK2	S164	S161F	161	Missense	distal	-3	no	20.404	20.495	EPSD;PhosphoSitePlus	COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	P50613	CDK7	P24941	CDK2	S164	G163W	163	Missense	proximal	-1	no	20.404	20.480	EPSD;PhosphoSitePlus	COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	P50613	CDK7	P24941	CDK2	S164	S161Y	161	Missense	distal	-3	no	20.404	20.423	EPSD;PhosphoSitePlus	COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	P50613	CDK7	P24941	CDK2	S164	A159D	159	Missense	distal	-5	no	20.404	20.436	EPSD;PhosphoSitePlus	COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	P50613	CDK7	P24941	CDK2	T170	V173D	173	Missense	distal	3	no	14.179	11.757	PhosphoSitePlus;EPSD	COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	P50613	CDK7	P24941	CDK2	T170	G163W	163	Missense	distal	-7	no	14.179	14.369	PhosphoSitePlus;EPSD	COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	P50613	CDK7	P24941	CDK2	T231	Q236H	236	Missense	distal	5	no	13.735	13.853	EPSD	COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	P06748	NPM1	P24941	CDK2	S10	R13S	13	Missense	distal	3	no	16.787	15.102	EPSD	COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	P06748	NPM1	P24941	CDK2	S10	P14L	14	Missense	distal	4	no	16.787	16.899	EPSD	COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	P06748	NPM1	P24941	CDK2	S70	G69D	69	Missense	proximal	-1	no	19.803	19.510	PhosphoSitePlus;EPSD	COSMIC;GDSC;CCLE	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	P06748	NPM1	P24941	CDK2	T95	V98L	98	Missense	distal	3	no	14.238	13.246	EPSD	COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	P06748	NPM1	P24941	CDK2	S106	G113V	113	Missense	distal	7	no	9.382	8.971	EPSD	COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	P06748	NPM1	P24941	CDK2	S106	I111N	111	Missense	distal	5	no	9.382	9.392	EPSD	COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	P06748	NPM1	P24941	CDK2	S125	S125L	125	Missense	central	0	yes	11.293	0.000	EPSD	COSMIC	8.148	Loss
CMGC_CDK_CDK2_CDK2_ST	P06748	NPM1	P24941	CDK2	S125	E129Q	129	Missense	distal	4	no	11.293	11.337	EPSD	COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	P06748	NPM1	P24941	CDK2	S125	D127N	127	Missense	proximal	2	no	11.293	11.225	EPSD	COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	P06748	NPM1	P24941	CDK2	T199	P200S	200	Missense	proximal	1	no	16.152	4.886	EPSD;PhosphoSitePlus	COSMIC	8.148	Loss
CMGC_CDK_CDK2_CDK2_ST	P06748	NPM1	P24941	CDK2	T199	S195F	195	Missense	distal	-4	no	16.152	15.190	EPSD;PhosphoSitePlus	COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	P06748	NPM1	P24941	CDK2	T219	G224R	224	Missense	distal	5	no	13.177	13.157	EPSD	COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	P06748	NPM1	P24941	CDK2	T234	F228S	228	Missense	distal	-6	no	11.174	11.169	EPSD;PhosphoSitePlus	COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	P06748	NPM1	P24941	CDK2	T234	S227F	227	Missense	distal	-7	no	11.174	11.725	EPSD;PhosphoSitePlus	COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	Q9BZL4	PPP1R12C	P24941	CDK2	S325	G329S	329	Missense	distal	4	no	8.432	8.565	EPSD	COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	Q9BZL4	PPP1R12C	P24941	CDK2	S399	P400L	400	Missense	proximal	1	no	15.462	5.641	EPSD	COSMIC	8.148	Loss
CMGC_CDK_CDK2_CDK2_ST	Q9BZL4	PPP1R12C	P24941	CDK2	S399	P403R	403	Missense	distal	4	no	15.462	15.342	EPSD	COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	Q9BZL4	PPP1R12C	P24941	CDK2	S404	P400L	400	Missense	distal	-4	no	11.770	11.712	EPSD	COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	Q9BZL4	PPP1R12C	P24941	CDK2	S404	P403R	403	Missense	proximal	-1	no	11.770	12.341	EPSD	COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	Q9BZL4	PPP1R12C	P24941	CDK2	S407	P400L	400	Missense	distal	-7	no	15.378	15.383	EPSD	COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	Q9BZL4	PPP1R12C	P24941	CDK2	S407	A414T	414	Missense	distal	7	no	15.378	14.689	EPSD	COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	Q9BZL4	PPP1R12C	P24941	CDK2	S407	P403R	403	Missense	distal	-4	no	15.378	15.135	EPSD	COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	Q9BZL4	PPP1R12C	P24941	CDK2	T472	R467C	467	Missense	distal	-5	no	11.320	11.354	EPSD	COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	Q9BZL4	PPP1R12C	P24941	CDK2	T474	P480L	480	Missense	distal	6	no	14.682	14.684	EPSD	COSMIC;CCLE	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	Q9BZL4	PPP1R12C	P24941	CDK2	T474	R467C	467	Missense	distal	-7	no	14.682	14.609	EPSD	COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	Q9BZL4	PPP1R12C	P24941	CDK2	S476	P480L	480	Missense	distal	4	no	12.262	12.374	EPSD	COSMIC;CCLE	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	Q9BZL4	PPP1R12C	P24941	CDK2	S509	A511E	511	Missense	proximal	2	no	18.481	18.553	PhosphoSitePlus	COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	Q9BZL4	PPP1R12C	P24941	CDK2	S509	A511V	511	Missense	proximal	2	no	18.481	18.578	PhosphoSitePlus	COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	Q9BZL4	PPP1R12C	P24941	CDK2	S526	S519F	519	Missense	distal	-7	no	7.975	8.527	EPSD	COSMIC	8.148	Gain
CMGC_CDK_CDK2_CDK2_ST	Q9BZL4	PPP1R12C	P24941	CDK2	S544	R551L	551	Missense	distal	7	no	9.059	8.600	EPSD	COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	Q9BZL4	PPP1R12C	P24941	CDK2	S544	R551C	551	Missense	distal	7	no	9.059	9.211	EPSD	COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	Q9BZL4	PPP1R12C	P24941	CDK2	S604	E600K	600	Missense	distal	-4	no	14.955	14.643	EPSD	COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	Q9BZL4	PPP1R12C	P24941	CDK2	S604	S604N	604	Missense	central	0	yes	14.955	0.000	EPSD	COSMIC	8.148	Loss
CMGC_CDK_CDK2_CDK2_ST	Q14194	CRMP1	P24941	CDK2	S304	A298V	298	Missense	distal	-6	no	11.035	11.038	EPSD	COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	Q14194	CRMP1	P24941	CDK2	S304	A298T	298	Missense	distal	-6	no	11.035	11.037	EPSD	COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	Q14194	CRMP1	P24941	CDK2	S304	A300T	300	Missense	distal	-4	no	11.035	11.261	EPSD	COSMIC;CCLE	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	Q14194	CRMP1	P24941	CDK2	S308	P314T	314	Missense	distal	6	no	13.825	13.832	EPSD	COSMIC;CCLE	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	Q14194	CRMP1	P24941	CDK2	S442	G441D	441	Missense	proximal	-1	no	15.250	14.957	EPSD	COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	Q14194	CRMP1	P24941	CDK2	S442	V445A	445	Missense	distal	3	no	15.250	14.130	EPSD	COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	Q14194	CRMP1	P24941	CDK2	S442	E435K	435	Missense	distal	-7	no	15.250	15.113	EPSD	COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	Q14194	CRMP1	P24941	CDK2	S448	G441D	441	Missense	distal	-7	no	9.431	9.348	EPSD	COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	Q14194	CRMP1	P24941	CDK2	S448	V453I	453	Missense	distal	5	no	9.431	9.557	EPSD	COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	Q14194	CRMP1	P24941	CDK2	S448	V445A	445	Missense	distal	-3	no	9.431	9.230	EPSD	COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	Q14194	CRMP1	P24941	CDK2	S448	G450C	450	Missense	proximal	2	no	9.431	9.459	EPSD	COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	Q14194	CRMP1	P24941	CDK2	T509	A508G	508	Missense	proximal	-1	no	12.420	13.738	PhosphoSitePlus	COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	Q14194	CRMP1	P24941	CDK2	T509	P515L	515	Missense	distal	6	no	12.420	12.421	PhosphoSitePlus	COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	Q14194	CRMP1	P24941	CDK2	T509	P510H	510	Missense	proximal	1	no	12.420	5.661	PhosphoSitePlus	COSMIC	8.148	Loss
CMGC_CDK_CDK2_CDK2_ST	Q14194	CRMP1	P24941	CDK2	T509	E505K	505	Missense	distal	-4	no	12.420	12.108	PhosphoSitePlus	COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	Q14194	CRMP1	P24941	CDK2	T509	E505D	505	Missense	distal	-4	no	12.420	12.716	PhosphoSitePlus	COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	Q14194	CRMP1	P24941	CDK2	T509	A516V	516	Missense	distal	7	no	12.420	12.293	PhosphoSitePlus	COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	Q14194	CRMP1	P24941	CDK2	T514	A508G	508	Missense	distal	-6	no	12.114	12.117	EPSD	COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	Q14194	CRMP1	P24941	CDK2	T514	S521Y	521	Missense	distal	7	no	12.114	12.535	EPSD	COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	Q14194	CRMP1	P24941	CDK2	T514	P515L	515	Missense	proximal	1	no	12.114	2.293	EPSD	COSMIC	8.148	Loss
CMGC_CDK_CDK2_CDK2_ST	Q14194	CRMP1	P24941	CDK2	T514	P510H	510	Missense	distal	-4	no	12.114	11.510	EPSD	COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	Q14194	CRMP1	P24941	CDK2	T514	A516V	516	Missense	proximal	2	no	12.114	12.212	EPSD	COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	Q14194	CRMP1	P24941	CDK2	S522	S522L	522	Missense	central	0	yes	15.211	0.000	EPSD	COSMIC	8.148	Loss
CMGC_CDK_CDK2_CDK2_ST	Q14194	CRMP1	P24941	CDK2	S522	S521Y	521	Missense	proximal	-1	no	15.211	16.121	EPSD	COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	Q14194	CRMP1	P24941	CDK2	S522	P515L	515	Missense	distal	-7	no	15.211	15.216	EPSD	COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	Q14194	CRMP1	P24941	CDK2	S522	Q527H	527	Missense	distal	5	no	15.211	15.329	EPSD	COSMIC;CCLE	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	Q14194	CRMP1	P24941	CDK2	S522	P528T	528	Missense	distal	6	no	15.211	15.219	EPSD	COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	Q14194	CRMP1	P24941	CDK2	S522	P528L	528	Missense	distal	6	no	15.211	15.212	EPSD	COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	Q14194	CRMP1	P24941	CDK2	S522	A516V	516	Missense	distal	-6	no	15.211	15.214	EPSD	COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	Q13416	ORC2	P24941	CDK2	T226	R230K	230	Missense	distal	4	no	14.715	15.237	EPSD;PhosphoSitePlus	COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	Q13416	ORC2	P24941	CDK2	S280	S280F	280	Missense	central	0	yes	14.755	0.000	EPSD	COSMIC	8.148	Loss
CMGC_CDK_CDK2_CDK2_ST	Q13416	ORC2	P24941	CDK2	S280	L275F	275	Missense	distal	-5	no	14.755	14.816	EPSD	COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	Q13416	ORC2	P24941	CDK2	S280	A285D	285	Missense	distal	5	no	14.755	14.919	EPSD	COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	Q13416	ORC2	P24941	CDK2	S280	S280P	280	Missense	central	0	yes	14.755	0.000	EPSD	COSMIC	8.148	Loss
CMGC_CDK_CDK2_CDK2_ST	Q13416	ORC2	P24941	CDK2	S280	S277N	277	Missense	distal	-3	no	14.755	14.681	EPSD	COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	Q13416	ORC2	P24941	CDK2	S280	S277R	277	Missense	distal	-3	no	14.755	14.848	EPSD	COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	Q96II8	LRCH3	P24941	CDK2	S16	S21L	21	Missense	distal	5	no	8.306	8.447	EPSD	COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	Q96II8	LRCH3	P24941	CDK2	S255	P257A	257	Missense	proximal	2	no	12.407	12.432	EPSD	COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	Q96II8	LRCH3	P24941	CDK2	S324	T329A	329	Missense	distal	5	no	10.108	10.144	EPSD	COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	Q96II8	LRCH3	P24941	CDK2	S352	E345Q	345	Missense	distal	-7	no	8.581	8.448	EPSD	COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	Q96II8	LRCH3	P24941	CDK2	S352	G359R	359	Missense	distal	7	no	8.581	8.401	EPSD	COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	Q96II8	LRCH3	P24941	CDK2	S419	R413Q	413	Missense	distal	-6	no	18.277	18.278	PhosphoSitePlus	COSMIC;GDSC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	Q96II8	LRCH3	P24941	CDK2	S419	P420S	420	Missense	proximal	1	no	18.277	7.011	PhosphoSitePlus	COSMIC	8.148	Loss
CMGC_CDK_CDK2_CDK2_ST	Q96II8	LRCH3	P24941	CDK2	T464	E467K	467	Missense	distal	3	no	6.117	8.203	EPSD	COSMIC	8.148	Gain
CMGC_CDK_CDK2_CDK2_ST	Q96II8	LRCH3	P24941	CDK2	S516	P522L	522	Missense	distal	6	no	18.026	18.027	EPSD	COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	Q96II8	LRCH3	P24941	CDK2	S516	P522Q	522	Missense	distal	6	no	18.026	18.031	EPSD	COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	Q96II8	LRCH3	P24941	CDK2	S516	H521P	521	Missense	distal	5	no	18.026	17.948	EPSD	COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	Q96II8	LRCH3	P24941	CDK2	S583	R576S	576	Missense	distal	-7	no	13.961	13.438	EPSD	COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	Q96II8	LRCH3	P24941	CDK2	S592	P598L	598	Missense	distal	6	no	13.948	13.949	EPSD	COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	Q96II8	LRCH3	P24941	CDK2	S628	L630V	630	Missense	proximal	2	no	11.754	11.983	EPSD	COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	Q96II8	LRCH3	P24941	CDK2	S628	P631S	631	Missense	distal	3	no	11.754	11.788	EPSD	COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	Q96II8	LRCH3	P24941	CDK2	S628	S633P	633	Missense	distal	5	no	11.754	11.855	EPSD	COSMIC;GDSC;CCLE	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	Q96II8	LRCH3	P24941	CDK2	S628	A627V	627	Missense	proximal	-1	no	11.754	11.981	EPSD	COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	Q96II8	LRCH3	P24941	CDK2	S628	P632L	632	Missense	distal	4	no	11.754	11.866	EPSD	COSMIC;CCLE	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	Q96II8	LRCH3	P24941	CDK2	S707	P706H	706	Missense	proximal	-1	no	13.135	13.254	EPSD	COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	Q12800	TFCP2	P24941	CDK2	T258	E263K	263	Missense	distal	5	no	16.635	16.502	EPSD;PhosphoSitePlus	COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	Q12800	TFCP2	P24941	CDK2	T258	R257L	257	Missense	proximal	-1	no	16.635	15.885	EPSD;PhosphoSitePlus	COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	Q12800	TFCP2	P24941	CDK2	T258	E252K	252	Missense	distal	-6	no	16.635	16.632	EPSD;PhosphoSitePlus	COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	Q12800	TFCP2	P24941	CDK2	S289	N295I	295	Missense	distal	6	no	12.343	12.340	PhosphoSitePlus;EPSD	COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	Q12800	TFCP2	P24941	CDK2	S291	N295I	295	Missense	distal	4	no	14.952	14.943	EPSD;PhosphoSitePlus	COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	Q12800	TFCP2	P24941	CDK2	S309	G306V	306	Missense	distal	-3	no	18.016	18.055	EPSD;PhosphoSitePlus	COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	Q12800	TFCP2	P24941	CDK2	S309	P314L	314	Missense	distal	5	no	18.016	18.056	EPSD;PhosphoSitePlus	COSMIC;GDSC;CCLE	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	Q02535	ID3	P24941	CDK2	S21	L22P	22	Missense	proximal	1	no	4.450	14.271	EPSD	COSMIC	8.148	Gain
CMGC_CDK_CDK2_CDK2_ST	P06400	RB1	P24941	CDK2	T5	P6S	6	Missense	proximal	1	no	12.968	1.702	EPSD	COSMIC	8.148	Loss
CMGC_CDK_CDK2_CDK2_ST	P06400	RB1	P24941	CDK2	T5	P2S	2	Missense	distal	-3	no	12.968	13.063	EPSD	COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	P06400	RB1	P24941	CDK2	T5	T5N	5	Missense	central	0	yes	12.968	0.000	EPSD	COSMIC	8.148	Loss
CMGC_CDK_CDK2_CDK2_ST	P06400	RB1	P24941	CDK2	T5	R7Q	7	Missense	proximal	2	no	12.968	12.868	EPSD	COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	P06400	RB1	P24941	CDK2	S37	G38F	38	Missense	proximal	1	no	8.308	0.810	EPSD	COSMIC	8.148	Loss
CMGC_CDK_CDK2_CDK2_ST	P06400	RB1	P24941	CDK2	S37	E30A	30	Missense	distal	-7	no	8.308	8.382	EPSD	COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	P06400	RB1	P24941	CDK2	S37	G38D	38	Missense	proximal	1	no	8.308	7.376	EPSD	COSMIC	8.148	Loss
CMGC_CDK_CDK2_CDK2_ST	P06400	RB1	P24941	CDK2	S37	D36N	36	Missense	proximal	-1	no	8.308	7.478	EPSD	COSMIC	8.148	Loss
CMGC_CDK_CDK2_CDK2_ST	P06400	RB1	P24941	CDK2	S37	D32N	32	Missense	distal	-5	no	8.308	8.269	EPSD	COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	P06400	RB1	P24941	CDK2	S230	K228R	228	Missense	proximal	-2	no	12.051	11.329	EPSD	COSMIC;GDSC;CCLE	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	P06400	RB1	P24941	CDK2	S230	I227N	227	Missense	distal	-3	no	12.051	12.052	EPSD	COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	P06400	RB1	P24941	CDK2	S230	P232L	232	Missense	proximal	2	no	12.051	11.944	EPSD	COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	P06400	RB1	P24941	CDK2	S249	V243A	243	Missense	distal	-6	no	15.721	15.718	EPSD;PhosphoSitePlus	COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	P06400	RB1	P24941	CDK2	S249	P250S	250	Missense	proximal	1	no	15.721	4.455	EPSD;PhosphoSitePlus	COSMIC	8.148	Loss
CMGC_CDK_CDK2_CDK2_ST	P06400	RB1	P24941	CDK2	T252	Q257R	257	Missense	distal	5	no	15.433	15.579	EPSD;PhosphoSitePlus	COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	P06400	RB1	P24941	CDK2	T252	P250S	250	Missense	proximal	-2	no	15.433	14.782	EPSD;PhosphoSitePlus	COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	P06400	RB1	P24941	CDK2	T356	E352K	352	Missense	distal	-4	no	17.127	16.816	PhosphoSitePlus;EPSD	COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	P06400	RB1	P24941	CDK2	T356	R358Q	358	Missense	proximal	2	no	17.127	17.028	PhosphoSitePlus;EPSD	COSMIC;CCLE	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	P06400	RB1	P24941	CDK2	T356	N361Y	361	Missense	distal	5	no	17.127	17.098	PhosphoSitePlus;EPSD	COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	P06400	RB1	P24941	CDK2	T373	P370S	370	Missense	distal	-3	no	17.326	17.421	EPSD;PhosphoSitePlus	COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	P06400	RB1	P24941	CDK2	T373	P374L	374	Missense	proximal	1	no	17.326	7.505	EPSD;PhosphoSitePlus	COSMIC	8.148	Loss
CMGC_CDK_CDK2_CDK2_ST	P06400	RB1	P24941	CDK2	T373	N367D	367	Missense	distal	-6	no	17.326	17.325	EPSD;PhosphoSitePlus	COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	P06400	RB1	P24941	CDK2	T373	P370L	370	Missense	distal	-3	no	17.326	17.255	EPSD;PhosphoSitePlus	COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	P06400	RB1	P24941	CDK2	S567	W563C	563	Missense	distal	-4	no	12.510	12.759	EPSD;PhosphoSitePlus	COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	P06400	RB1	P24941	CDK2	S567	S560P	560	Missense	distal	-7	no	12.510	12.689	EPSD;PhosphoSitePlus	COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	P06400	RB1	P24941	CDK2	S567	L564V	564	Missense	distal	-3	no	12.510	12.723	EPSD;PhosphoSitePlus	COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	P06400	RB1	P24941	CDK2	S567	L572F	572	Missense	distal	5	no	12.510	12.687	EPSD;PhosphoSitePlus	COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	P06400	RB1	P24941	CDK2	S608	R611S	611	Missense	distal	3	no	15.720	14.035	EPSD;PhosphoSitePlus	COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	P06400	RB1	P24941	CDK2	S608	S612P	612	Missense	distal	4	no	15.720	15.706	EPSD;PhosphoSitePlus	COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	P06400	RB1	P24941	CDK2	S608	Y606C	606	Missense	proximal	-2	no	15.720	15.222	EPSD;PhosphoSitePlus	COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	P06400	RB1	P24941	CDK2	S608	P609S	609	Missense	proximal	1	no	15.720	4.454	EPSD;PhosphoSitePlus	COSMIC	8.148	Loss
CMGC_CDK_CDK2_CDK2_ST	P06400	RB1	P24941	CDK2	S608	M605T	605	Missense	distal	-3	no	15.720	15.312	EPSD;PhosphoSitePlus	COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	P06400	RB1	P24941	CDK2	S608	L607V	607	Missense	proximal	-1	no	15.720	15.856	EPSD;PhosphoSitePlus	COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	P06400	RB1	P24941	CDK2	S608	L607I	607	Missense	proximal	-1	no	15.720	15.882	EPSD;PhosphoSitePlus	COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	P06400	RB1	P24941	CDK2	S612	R611S	611	Missense	proximal	-1	no	17.700	16.659	EPSD;PhosphoSitePlus	COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	P06400	RB1	P24941	CDK2	S612	S612P	612	Missense	central	0	yes	17.700	0.000	EPSD;PhosphoSitePlus	COSMIC	8.148	Loss
CMGC_CDK_CDK2_CDK2_ST	P06400	RB1	P24941	CDK2	S612	Y606C	606	Missense	distal	-6	no	17.700	17.706	EPSD;PhosphoSitePlus	COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	P06400	RB1	P24941	CDK2	S612	P609S	609	Missense	distal	-3	no	17.700	17.796	EPSD;PhosphoSitePlus	COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	P06400	RB1	P24941	CDK2	S612	M605T	605	Missense	distal	-7	no	17.700	17.197	EPSD;PhosphoSitePlus	COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	P06400	RB1	P24941	CDK2	S612	L607V	607	Missense	distal	-5	no	17.700	17.720	EPSD;PhosphoSitePlus	COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	P06400	RB1	P24941	CDK2	S612	L607I	607	Missense	distal	-5	no	17.700	17.728	EPSD;PhosphoSitePlus	COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	P06400	RB1	P24941	CDK2	T620	R621P	621	Missense	proximal	1	no	1.804	11.602	EPSD	COSMIC	8.148	Gain
CMGC_CDK_CDK2_CDK2_ST	P06400	RB1	P24941	CDK2	T633	S634P	634	Missense	proximal	1	no	0.414	11.680	EPSD	COSMIC	8.148	Gain
CMGC_CDK_CDK2_CDK2_ST	P06400	RB1	P24941	CDK2	S780	P776R	776	Missense	distal	-4	no	13.523	13.281	EPSD	COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	P06400	RB1	P24941	CDK2	S780	H784Y	784	Missense	distal	4	no	13.523	13.960	EPSD	COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	P06400	RB1	P24941	CDK2	S780	P777S	777	Missense	distal	-3	no	13.523	13.619	EPSD	COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	P06400	RB1	P24941	CDK2	S780	P786S	786	Missense	distal	6	no	13.523	13.525	EPSD	COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	P06400	RB1	P24941	CDK2	S780	S773F	773	Missense	distal	-7	no	13.523	14.075	EPSD	COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	P06400	RB1	P24941	CDK2	S788	S795L	795	Missense	distal	7	no	15.922	16.104	EPSD	COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	P06400	RB1	P24941	CDK2	S788	H784Y	784	Missense	distal	-4	no	15.922	16.991	EPSD	COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	P06400	RB1	P24941	CDK2	S788	S794I	794	Missense	distal	6	no	15.922	15.921	EPSD	COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	P06400	RB1	P24941	CDK2	S788	P786S	786	Missense	proximal	-2	no	15.922	15.271	EPSD	COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	P06400	RB1	P24941	CDK2	S788	P793S	793	Missense	distal	5	no	15.922	15.821	EPSD	COSMIC;CCLE	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	P06400	RB1	P24941	CDK2	S795	S795L	795	Missense	central	0	yes	14.101	0.000	EPSD	COSMIC	8.148	Loss
CMGC_CDK_CDK2_CDK2_ST	P06400	RB1	P24941	CDK2	S795	G802R	802	Missense	distal	7	no	14.101	13.921	EPSD	COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	P06400	RB1	P24941	CDK2	S795	R798Q	798	Missense	distal	3	no	14.101	12.357	EPSD	COSMIC;GDSC;CCLE	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	P06400	RB1	P24941	CDK2	S795	S794I	794	Missense	proximal	-1	no	14.101	14.555	EPSD	COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	P06400	RB1	P24941	CDK2	S795	G801A	801	Missense	distal	6	no	14.101	14.108	EPSD	COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	P06400	RB1	P24941	CDK2	S795	P793S	793	Missense	proximal	-2	no	14.101	13.450	EPSD	COSMIC;CCLE	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	P06400	RB1	P24941	CDK2	S807	G802R	802	Missense	distal	-5	no	16.149	16.116	EPSD;PhosphoSitePlus	COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	P06400	RB1	P24941	CDK2	S807	K814T	814	Missense	distal	7	no	16.149	16.131	EPSD;PhosphoSitePlus	COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	P06400	RB1	P24941	CDK2	S807	G801A	801	Missense	distal	-6	no	16.149	16.145	EPSD;PhosphoSitePlus	COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	P06400	RB1	P24941	CDK2	S811	G818S	818	Missense	distal	7	no	16.659	15.837	EPSD;PhosphoSitePlus	COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	P06400	RB1	P24941	CDK2	S811	G818C	818	Missense	distal	7	no	16.659	16.630	EPSD;PhosphoSitePlus	COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	P06400	RB1	P24941	CDK2	S811	K814T	814	Missense	distal	3	no	16.659	13.837	EPSD;PhosphoSitePlus	COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	P06400	RB1	P24941	CDK2	T821	G818S	818	Missense	distal	-3	no	14.278	14.270	EPSD;PhosphoSitePlus	COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	P06400	RB1	P24941	CDK2	T821	P822S	822	Missense	proximal	1	no	14.278	3.012	EPSD;PhosphoSitePlus	COSMIC	8.148	Loss
CMGC_CDK_CDK2_CDK2_ST	P06400	RB1	P24941	CDK2	T821	K814T	814	Missense	distal	-7	no	14.278	14.322	EPSD;PhosphoSitePlus	COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	P06400	RB1	P24941	CDK2	T826	S829L	829	Missense	distal	3	no	15.388	14.970	EPSD;PhosphoSitePlus	COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	P06400	RB1	P24941	CDK2	T826	P822S	822	Missense	distal	-4	no	15.388	15.742	EPSD;PhosphoSitePlus	COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	O00267	SUPT5H	P24941	CDK2	S120	R123C	123	Missense	distal	3	no	9.341	2.977	EPSD	COSMIC	8.148	Loss
CMGC_CDK_CDK2_CDK2_ST	O00267	SUPT5H	P24941	CDK2	S120	R124C	124	Missense	distal	4	no	9.341	8.714	EPSD	COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	O00267	SUPT5H	P24941	CDK2	S120	R119H	119	Missense	proximal	-1	no	9.341	8.890	EPSD	COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	O00267	SUPT5H	P24941	CDK2	T208	V215I	215	Missense	distal	7	no	16.583	16.381	EPSD	COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	O00267	SUPT5H	P24941	CDK2	S666	V659M	659	Missense	distal	-7	no	13.176	13.657	EPSD;PhosphoSitePlus	COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	O00267	SUPT5H	P24941	CDK2	S666	M665T	665	Missense	proximal	-1	no	13.176	11.863	EPSD;PhosphoSitePlus	COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	O00267	SUPT5H	P24941	CDK2	S666	P672L	672	Missense	distal	6	no	13.176	13.177	EPSD;PhosphoSitePlus	COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	O00267	SUPT5H	P24941	CDK2	S671	M665T	665	Missense	distal	-6	no	15.389	15.381	EPSD	COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	O00267	SUPT5H	P24941	CDK2	S671	P672L	672	Missense	proximal	1	no	15.389	5.568	EPSD	COSMIC	8.148	Loss
CMGC_CDK_CDK2_CDK2_ST	O00267	SUPT5H	P24941	CDK2	S691	R696L	696	Missense	distal	5	no	8.160	8.094	EPSD	COSMIC	8.148	Loss
CMGC_CDK_CDK2_CDK2_ST	O00267	SUPT5H	P24941	CDK2	S691	R696Q	696	Missense	distal	5	no	8.160	8.014	EPSD	COSMIC	8.148	Loss
CMGC_CDK_CDK2_CDK2_ST	O00267	SUPT5H	P24941	CDK2	S695	R696L	696	Missense	proximal	1	no	8.189	8.166	EPSD	COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	O00267	SUPT5H	P24941	CDK2	S695	D702G	702	Missense	distal	7	no	8.189	8.172	EPSD	COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	O00267	SUPT5H	P24941	CDK2	S695	D702Y	702	Missense	distal	7	no	8.189	7.772	EPSD	COSMIC	8.148	Loss
CMGC_CDK_CDK2_CDK2_ST	O00267	SUPT5H	P24941	CDK2	S695	R696Q	696	Missense	proximal	1	no	8.189	10.076	EPSD	COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	O00267	SUPT5H	P24941	CDK2	S730	A727T	727	Missense	distal	-3	no	8.367	8.386	EPSD	COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	O00267	SUPT5H	P24941	CDK2	S738	T739P	739	Missense	proximal	1	no	5.294	15.251	EPSD	COSMIC	8.148	Gain
CMGC_CDK_CDK2_CDK2_ST	O00267	SUPT5H	P24941	CDK2	S780	P785S	785	Missense	distal	5	no	11.206	11.105	EPSD	COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	O00267	SUPT5H	P24941	CDK2	T784	P785S	785	Missense	proximal	1	no	13.978	2.713	EPSD	COSMIC	8.148	Loss
CMGC_CDK_CDK2_CDK2_ST	O00267	SUPT5H	P24941	CDK2	T784	G788D	788	Missense	distal	4	no	13.978	14.033	EPSD	COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	O00267	SUPT5H	P24941	CDK2	T784	G788S	788	Missense	distal	4	no	13.978	14.112	EPSD	COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	O00267	SUPT5H	P24941	CDK2	T784	S789L	789	Missense	distal	5	no	13.978	14.119	EPSD	COSMIC;GDSC;CCLE	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	O00267	SUPT5H	P24941	CDK2	T791	P785S	785	Missense	distal	-6	no	12.170	12.169	EPSD;PhosphoSitePlus	COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	O00267	SUPT5H	P24941	CDK2	T791	G788D	788	Missense	distal	-3	no	12.170	12.132	EPSD;PhosphoSitePlus	COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	O00267	SUPT5H	P24941	CDK2	T791	G788S	788	Missense	distal	-3	no	12.170	12.162	EPSD;PhosphoSitePlus	COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	O00267	SUPT5H	P24941	CDK2	T791	S789L	789	Missense	proximal	-2	no	12.170	12.597	EPSD;PhosphoSitePlus	COSMIC;GDSC;CCLE	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	O00267	SUPT5H	P24941	CDK2	T814	G819W	819	Missense	distal	5	no	13.463	13.609	EPSD	COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	O00267	SUPT5H	P24941	CDK2	T814	A816V	816	Missense	proximal	2	no	13.463	13.561	EPSD	COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	O00267	SUPT5H	P24941	CDK2	T814	S818G	818	Missense	distal	4	no	13.463	13.329	EPSD	COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	O00267	SUPT5H	P24941	CDK2	T828	E834K	834	Missense	distal	6	no	15.154	15.165	EPSD	COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	O00267	SUPT5H	P24941	CDK2	T845	D841N	841	Missense	distal	-4	no	12.348	11.960	EPSD	COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	O00267	SUPT5H	P24941	CDK2	T845	P848L	848	Missense	distal	3	no	12.348	11.965	EPSD	COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	O00267	SUPT5H	P24941	CDK2	T845	P844L	844	Missense	proximal	-1	no	12.348	12.169	EPSD	COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	O00267	SUPT5H	P24941	CDK2	S847	D841N	841	Missense	distal	-6	no	14.178	14.179	EPSD	COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	O00267	SUPT5H	P24941	CDK2	S847	P848L	848	Missense	proximal	1	no	14.178	4.357	EPSD	COSMIC	8.148	Loss
CMGC_CDK_CDK2_CDK2_ST	O00267	SUPT5H	P24941	CDK2	S847	P844L	844	Missense	distal	-3	no	14.178	14.107	EPSD	COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	O00267	SUPT5H	P24941	CDK2	T854	P857S	857	Missense	distal	3	no	13.972	14.006	EPSD	COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	O00267	SUPT5H	P24941	CDK2	T854	P857L	857	Missense	distal	3	no	13.972	13.588	EPSD	COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	O00267	SUPT5H	P24941	CDK2	T859	D864H	864	Missense	distal	5	no	14.122	14.026	EPSD	COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	O00267	SUPT5H	P24941	CDK2	T859	P857S	857	Missense	proximal	-2	no	14.122	13.471	EPSD	COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	O00267	SUPT5H	P24941	CDK2	T859	S866L	866	Missense	distal	7	no	14.122	14.305	EPSD	COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	O00267	SUPT5H	P24941	CDK2	T859	P857L	857	Missense	proximal	-2	no	14.122	13.898	EPSD	COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	O00267	SUPT5H	P24941	CDK2	S867	D864H	864	Missense	distal	-3	no	15.527	15.608	EPSD	COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	O00267	SUPT5H	P24941	CDK2	S867	P872A	872	Missense	distal	5	no	15.527	15.537	EPSD	COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	O00267	SUPT5H	P24941	CDK2	S867	S866L	866	Missense	proximal	-1	no	15.527	15.818	EPSD	COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	O00267	SUPT5H	P24941	CDK2	S867	P868A	868	Missense	proximal	1	no	15.527	1.123	EPSD	COSMIC	8.148	Loss
CMGC_CDK_CDK2_CDK2_ST	O00267	SUPT5H	P24941	CDK2	T878	P872A	872	Missense	distal	-6	no	11.338	11.337	EPSD	COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	O00267	SUPT5H	P24941	CDK2	T881	N886S	886	Missense	distal	5	no	14.252	14.048	EPSD	COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	O00267	SUPT5H	P24941	CDK2	S897	P892S	892	Missense	distal	-5	no	12.335	12.291	EPSD	COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	O00267	SUPT5H	P24941	CDK2	S951	P958L	958	Missense	distal	7	no	14.085	14.115	EPSD	COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	O00267	SUPT5H	P24941	CDK2	S951	P958S	958	Missense	distal	7	no	14.085	13.933	EPSD	COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	O00267	SUPT5H	P24941	CDK2	T954	P958L	958	Missense	distal	4	no	15.122	15.234	EPSD	COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	O00267	SUPT5H	P24941	CDK2	T954	P958S	958	Missense	distal	4	no	15.122	15.135	EPSD	COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	O00267	SUPT5H	P24941	CDK2	S959	P958L	958	Missense	proximal	-1	no	14.507	14.327	EPSD	COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	O00267	SUPT5H	P24941	CDK2	S959	P958S	958	Missense	proximal	-1	no	14.507	14.036	EPSD	COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	O00267	SUPT5H	P24941	CDK2	S959	G962V	962	Missense	distal	3	no	14.507	15.216	EPSD	COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	O00267	SUPT5H	P24941	CDK2	T967	T967P	967	Missense	central	0	yes	13.793	0.000	EPSD	COSMIC	8.148	Loss
CMGC_CDK_CDK2_CDK2_ST	O00267	SUPT5H	P24941	CDK2	T967	G962V	962	Missense	distal	-5	no	13.793	13.744	EPSD	COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	O00267	SUPT5H	P24941	CDK2	S970	T967P	967	Missense	distal	-3	no	8.711	8.750	EPSD	COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	O00267	SUPT5H	P24941	CDK2	T1034	N1039S	1039	Missense	distal	5	no	15.546	15.342	EPSD	COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	O00267	SUPT5H	P24941	CDK2	T1034	K1040R	1040	Missense	distal	6	no	15.546	15.521	EPSD	COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	O00267	SUPT5H	P24941	CDK2	T1034	N1039K	1039	Missense	distal	5	no	15.546	15.389	EPSD	COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	Q9UQR0	SCML2	P24941	CDK2	S256	S261I	261	Missense	distal	5	no	13.781	13.975	EPSD	COSMIC;GDSC;CCLE	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	Q9UQR0	SCML2	P24941	CDK2	S256	S255Y	255	Missense	proximal	-1	no	13.781	14.691	EPSD	COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	Q9UQR0	SCML2	P24941	CDK2	S267	S261I	261	Missense	distal	-6	no	13.843	13.846	EPSD	COSMIC;GDSC;CCLE	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	Q9UQR0	SCML2	P24941	CDK2	S511	V508A	508	Missense	distal	-3	no	13.957	13.755	EPSD;PhosphoSitePlus	COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	Q9UQR0	SCML2	P24941	CDK2	S511	K516R	516	Missense	distal	5	no	13.957	14.117	EPSD;PhosphoSitePlus	COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	Q9UQR0	SCML2	P24941	CDK2	S511	S511F	511	Missense	central	0	yes	13.957	0.000	EPSD;PhosphoSitePlus	COSMIC;GDSC;CCLE	8.148	Loss
CMGC_CDK_CDK2_CDK2_ST	Q9UQR0	SCML2	P24941	CDK2	S590	P591S	591	Missense	proximal	1	no	11.413	0.147	EPSD;PhosphoSitePlus	COSMIC	8.148	Loss
CMGC_CDK_CDK2_CDK2_ST	Q9UQR0	SCML2	P24941	CDK2	S594	P591S	591	Missense	distal	-3	no	14.045	14.140	EPSD	COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	P10275	AR	P24941	CDK2	S83	Q79E	79	Missense	distal	-4	no	11.215	11.663	EPSD	COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	P10275	AR	P24941	CDK2	S83	Q86K	86	Missense	distal	3	no	11.215	13.947	EPSD	COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	P10275	AR	P24941	CDK2	S83	E81Q	81	Missense	proximal	-2	no	11.215	11.763	EPSD	COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	P10275	AR	P24941	CDK2	S83	Q90H	90	Missense	distal	7	no	11.215	11.501	EPSD	COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	P10275	AR	P24941	CDK2	S83	Q79R	79	Missense	distal	-4	no	11.215	11.190	EPSD	COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	P10275	AR	P24941	CDK2	S83	P84H	84	Missense	proximal	1	no	11.215	4.456	EPSD	COSMIC	8.148	Loss
CMGC_CDK_CDK2_CDK2_ST	P10275	AR	P24941	CDK2	S96	S96Y	96	Missense	central	0	yes	13.938	0.000	PhosphoSitePlus	COSMIC	8.148	Loss
CMGC_CDK_CDK2_CDK2_ST	P10275	AR	P24941	CDK2	S96	Q90H	90	Missense	distal	-6	no	13.938	13.939	PhosphoSitePlus	COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	P10275	AR	P24941	CDK2	S96	S96F	96	Missense	central	0	yes	13.938	0.000	PhosphoSitePlus	COSMIC	8.148	Loss
CMGC_CDK_CDK2_CDK2_ST	P10275	AR	P24941	CDK2	S258	L257P	257	Missense	proximal	-1	no	13.449	13.629	EPSD	COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	P10275	AR	P24941	CDK2	S258	R264Q	264	Missense	distal	6	no	13.449	13.471	EPSD	COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	P10275	AR	P24941	CDK2	S258	E252K	252	Missense	distal	-6	no	13.449	13.447	EPSD	COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	P10275	AR	P24941	CDK2	S258	E255K	255	Missense	distal	-3	no	13.449	13.234	EPSD	COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	P10275	AR	P24941	CDK2	T282	R280H	280	Missense	proximal	-2	no	10.776	11.002	EPSD	COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	P10275	AR	P24941	CDK2	T282	E289G	289	Missense	distal	7	no	10.776	11.402	EPSD	COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	P10275	AR	P24941	CDK2	T282	P276S	276	Missense	distal	-6	no	10.776	10.775	EPSD	COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	P10275	AR	P24941	CDK2	T282	P283S	283	Missense	proximal	1	no	10.776	-0.490	EPSD	COSMIC	8.148	Loss
CMGC_CDK_CDK2_CDK2_ST	P10275	AR	P24941	CDK2	T282	A278T	278	Missense	distal	-4	no	10.776	11.001	EPSD	COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	P10275	AR	P24941	CDK2	T282	A285D	285	Missense	distal	3	no	10.776	9.474	EPSD	COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	P10275	AR	P24941	CDK2	T282	A278V	278	Missense	distal	-4	no	10.776	10.787	EPSD	COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	P10275	AR	P24941	CDK2	T282	A285V	285	Missense	distal	3	no	10.776	11.896	EPSD	COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	P10275	AR	P24941	CDK2	S310	D305N	305	Missense	distal	-5	no	17.226	17.188	EPSD	COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	P10275	AR	P24941	CDK2	S310	S310F	310	Missense	central	0	yes	17.226	0.000	EPSD	COSMIC	8.148	Loss
CMGC_CDK_CDK2_CDK2_ST	P10275	AR	P24941	CDK2	S310	E304K	304	Missense	distal	-6	no	17.226	17.224	EPSD	COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	P10275	AR	P24941	CDK2	S310	T306I	306	Missense	distal	-4	no	17.226	16.909	EPSD	COSMIC;GDSC;CCLE	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	P10275	AR	P24941	CDK2	S310	F312L	312	Missense	proximal	2	no	17.226	16.868	EPSD	COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	P10275	AR	P24941	CDK2	S424	A430T	430	Missense	distal	6	no	9.007	9.019	EPSD	COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	P10275	AR	P24941	CDK2	S424	A420E	420	Missense	distal	-4	no	9.007	9.296	EPSD	COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	P10275	AR	P24941	CDK2	S424	G421V	421	Missense	distal	-3	no	9.007	9.046	EPSD	COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	P10275	AR	P24941	CDK2	S424	A430S	430	Missense	distal	6	no	9.007	9.012	EPSD	COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	P10275	AR	P24941	CDK2	S424	G421R	421	Missense	distal	-3	no	9.007	9.092	EPSD	COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	P10275	AR	P24941	CDK2	S424	A417E	417	Missense	distal	-7	no	9.007	8.932	EPSD	COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	P10275	AR	P24941	CDK2	S424	A417V	417	Missense	distal	-7	no	9.007	8.862	EPSD	COSMIC;CCLE	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	P10275	AR	P24941	CDK2	S424	A417T	417	Missense	distal	-7	no	9.007	8.839	EPSD	COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	P10275	AR	P24941	CDK2	S424	S424C	424	Missense	central	0	yes	9.007	0.000	EPSD	COSMIC	8.148	Loss
CMGC_CDK_CDK2_CDK2_ST	P10275	AR	P24941	CDK2	S424	S424F	424	Missense	central	0	yes	9.007	0.000	EPSD	COSMIC	8.148	Loss
CMGC_CDK_CDK2_CDK2_ST	P10275	AR	P24941	CDK2	S426	A430T	430	Missense	distal	4	no	17.067	17.310	EPSD	COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	P10275	AR	P24941	CDK2	S426	A420E	420	Missense	distal	-6	no	17.067	17.071	EPSD	COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	P10275	AR	P24941	CDK2	S426	G421V	421	Missense	distal	-5	no	17.067	17.018	EPSD	COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	P10275	AR	P24941	CDK2	S426	A430S	430	Missense	distal	4	no	17.067	17.040	EPSD	COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	P10275	AR	P24941	CDK2	S426	G421R	421	Missense	distal	-5	no	17.067	17.034	EPSD	COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	P10275	AR	P24941	CDK2	S426	S433L	433	Missense	distal	7	no	17.067	17.249	EPSD	COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	P10275	AR	P24941	CDK2	S426	S424C	424	Missense	proximal	-2	no	17.067	16.657	EPSD	COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	P10275	AR	P24941	CDK2	S426	S424F	424	Missense	proximal	-2	no	17.067	16.605	EPSD	COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	P10275	AR	P24941	CDK2	S516	P515H	515	Missense	proximal	-1	no	9.037	9.156	EPSD	COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	P10275	AR	P24941	CDK2	S516	E523K	523	Missense	distal	7	no	9.037	8.707	EPSD	COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	P10275	AR	P24941	CDK2	S516	P515S	515	Missense	proximal	-1	no	9.037	8.566	EPSD	COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	P10275	AR	P24941	CDK2	S651	A646D	646	Missense	distal	-5	no	16.006	16.038	EPSD	COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	P10275	AR	P24941	CDK2	S651	S648R	648	Missense	distal	-3	no	16.006	16.099	EPSD	COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	P10275	AR	P24941	CDK2	S651	S648N	648	Missense	distal	-3	no	16.006	15.931	EPSD	COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	P10275	AR	P24941	CDK2	S651	E654K	654	Missense	distal	3	no	16.006	18.091	EPSD	COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	P10275	AR	P24941	CDK2	S651	S647F	647	Missense	distal	-4	no	16.006	15.044	EPSD	COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	P10275	AR	P24941	CDK2	S651	E655D	655	Missense	distal	4	no	16.006	15.924	EPSD	COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	P10275	AR	P24941	CDK2	S792	G796E	796	Missense	distal	4	no	8.373	8.509	EPSD	COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	P10275	AR	P24941	CDK2	S792	L798P	798	Missense	distal	6	no	8.373	8.371	EPSD	COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	P10275	AR	P24941	CDK2	S792	Q799E	799	Missense	distal	7	no	8.373	8.572	EPSD	COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	P10275	AR	P24941	CDK2	S792	S792F	792	Missense	central	0	yes	8.373	0.000	EPSD	COSMIC	8.148	Loss
CMGC_CDK_CDK2_CDK2_ST	P10275	AR	P24941	CDK2	S792	E794G	794	Missense	proximal	2	no	8.373	8.394	EPSD	COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	P10275	AR	P24941	CDK2	S792	S792P	792	Missense	central	0	yes	8.373	0.000	EPSD	COSMIC	8.148	Loss
CMGC_CDK_CDK2_CDK2_ST	P10275	AR	P24941	CDK2	S792	H790Q	790	Missense	proximal	-2	no	8.373	8.815	EPSD	COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	P10275	AR	P24941	CDK2	S792	E794D	794	Missense	proximal	2	no	8.373	8.273	EPSD	COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	O43395	PRPF3	P24941	CDK2	S106	E104K	104	Missense	proximal	-2	no	8.829	9.430	EPSD	COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	O43395	PRPF3	P24941	CDK2	S164	I163V	163	Missense	proximal	-1	no	13.379	13.353	EPSD	COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	O43395	PRPF3	P24941	CDK2	S164	S161N	161	Missense	distal	-3	no	13.379	13.304	EPSD	COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	O43395	PRPF3	P24941	CDK2	S164	P165H	165	Missense	proximal	1	no	13.379	6.620	EPSD	COSMIC	8.148	Loss
CMGC_CDK_CDK2_CDK2_ST	O43395	PRPF3	P24941	CDK2	T167	I163V	163	Missense	distal	-4	no	14.827	14.929	PhosphoSitePlus	COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	O43395	PRPF3	P24941	CDK2	T167	P165H	165	Missense	proximal	-2	no	14.827	13.817	PhosphoSitePlus	COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	O43395	PRPF3	P24941	CDK2	T172	P165H	165	Missense	distal	-7	no	13.442	13.565	EPSD	COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	O43395	PRPF3	P24941	CDK2	T254	E260Q	260	Missense	distal	6	no	11.765	11.774	EPSD	COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	O43395	PRPF3	P24941	CDK2	T254	T251A	251	Missense	distal	-3	no	11.765	11.746	EPSD	COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	O43395	PRPF3	P24941	CDK2	T254	I257T	257	Missense	distal	3	no	11.765	12.319	EPSD	COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	O43395	PRPF3	P24941	CDK2	S320	R325C	325	Missense	distal	5	no	10.036	10.163	EPSD	COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	O43395	PRPF3	P24941	CDK2	S320	R325H	325	Missense	distal	5	no	10.036	10.008	EPSD	COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	O43395	PRPF3	P24941	CDK2	T432	P426A	426	Missense	distal	-6	no	14.759	14.758	EPSD	COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	O43395	PRPF3	P24941	CDK2	S619	E621K	621	Missense	proximal	2	no	9.117	8.879	EPSD	COSMIC;GDSC;CCLE	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	P50750	CDK9	P24941	CDK2	S175	R172W	172	Missense	distal	-3	no	8.210	8.291	EPSD	COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	P50750	CDK9	P24941	CDK2	S347	A340T	340	Missense	distal	-7	no	8.180	8.013	EPSD	COSMIC;GDSC;CCLE	8.148	Loss
CMGC_CDK_CDK2_CDK2_ST	P50750	CDK9	P24941	CDK2	S347	R343C	343	Missense	distal	-4	no	8.180	7.671	EPSD	COSMIC	8.148	Loss
CMGC_CDK_CDK2_CDK2_ST	P50750	CDK9	P24941	CDK2	S347	S347C	347	Missense	central	0	yes	8.180	0.000	EPSD	COSMIC;GDSC;CCLE	8.148	Loss
CMGC_CDK_CDK2_CDK2_ST	Q9Y676	MRPS18B	P24941	CDK2	S49	S49Y	49	Missense	central	0	yes	18.412	0.000	PhosphoSitePlus	COSMIC	8.148	Loss
CMGC_CDK_CDK2_CDK2_ST	P46527	CDKN1B	P24941	CDK2	S10	R5L	5	Missense	distal	-5	no	12.148	12.113	EPSD	COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	P46527	CDKN1B	P24941	CDK2	S10	E14K	14	Missense	distal	4	no	12.148	12.533	EPSD	COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	P46527	CDKN1B	P24941	CDK2	S10	M16T	16	Missense	distal	6	no	12.148	12.175	EPSD	COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	P46527	CDKN1B	P24941	CDK2	S10	N3D	3	Missense	distal	-7	no	12.148	12.471	EPSD	COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	P46527	CDKN1B	P24941	CDK2	S10	P11S	11	Missense	proximal	1	no	12.148	0.882	EPSD	COSMIC	8.148	Loss
CMGC_CDK_CDK2_CDK2_ST	P46527	CDKN1B	P24941	CDK2	S10	S12N	12	Missense	proximal	2	no	12.148	12.011	EPSD	COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	P46527	CDKN1B	P24941	CDK2	S10	D17E	17	Missense	distal	7	no	12.148	11.506	EPSD	COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	P46527	CDKN1B	P24941	CDK2	S110	Q107R	107	Missense	distal	-3	no	9.560	9.691	EPSD	COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	P46527	CDKN1B	P24941	CDK2	S110	D108N	108	Missense	proximal	-2	no	9.560	8.352	EPSD	COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	P46527	CDKN1B	P24941	CDK2	S110	A116T	116	Missense	distal	6	no	9.560	9.572	EPSD	COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	P46527	CDKN1B	P24941	CDK2	S178	V184L	184	Missense	distal	6	no	15.197	15.199	EPSD	COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	P46527	CDKN1B	P24941	CDK2	S178	G182D	182	Missense	distal	4	no	15.197	15.251	EPSD	COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	P46527	CDKN1B	P24941	CDK2	T187	V184L	184	Missense	distal	-3	no	16.370	16.156	EPSD;PhosphoSitePlus	COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	P46527	CDKN1B	P24941	CDK2	T187	G182D	182	Missense	distal	-5	no	16.370	16.348	EPSD;PhosphoSitePlus	COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	P46527	CDKN1B	P24941	CDK2	T187	R194K	194	Missense	distal	7	no	16.370	15.594	EPSD;PhosphoSitePlus	COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	Q13415	ORC1	P24941	CDK2	S199	T203I	203	Missense	distal	4	no	13.086	12.774	EPSD	COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	Q13415	ORC1	P24941	CDK2	S199	A205T	205	Missense	distal	6	no	13.086	13.098	EPSD	COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	Q13415	ORC1	P24941	CDK2	T203	T203I	203	Missense	central	0	yes	13.636	0.000	EPSD	COSMIC	8.148	Loss
CMGC_CDK_CDK2_CDK2_ST	Q13415	ORC1	P24941	CDK2	T203	A205T	205	Missense	proximal	2	no	13.636	13.434	EPSD	COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	Q13415	ORC1	P24941	CDK2	T224	A218T	218	Missense	distal	-6	no	11.701	11.702	EPSD	COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	Q13415	ORC1	P24941	CDK2	T224	S217P	217	Missense	distal	-7	no	11.701	11.881	EPSD	COSMIC;GDSC;CCLE	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	Q13415	ORC1	P24941	CDK2	S258	T251N	251	Missense	distal	-7	no	15.023	14.944	EPSD;PhosphoSitePlus	COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	Q13415	ORC1	P24941	CDK2	S287	A292V	292	Missense	distal	5	no	14.037	13.994	EPSD	COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	Q13415	ORC1	P24941	CDK2	S287	P288L	288	Missense	proximal	1	no	14.037	4.216	EPSD	COSMIC	8.148	Loss
CMGC_CDK_CDK2_CDK2_ST	Q13415	ORC1	P24941	CDK2	S311	T304A	304	Missense	distal	-7	no	14.749	14.916	EPSD	COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	Q13415	ORC1	P24941	CDK2	S311	R315H	315	Missense	distal	4	no	14.749	14.632	EPSD	COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	Q13415	ORC1	P24941	CDK2	S311	P312S	312	Missense	proximal	1	no	14.749	3.483	EPSD	COSMIC;GDSC;CCLE	8.148	Loss
CMGC_CDK_CDK2_CDK2_ST	Q13415	ORC1	P24941	CDK2	S311	D306G	306	Missense	distal	-5	no	14.749	14.771	EPSD	COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	Q13415	ORC1	P24941	CDK2	T337	L336F	336	Missense	proximal	-1	no	14.126	15.092	EPSD	COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	Q13415	ORC1	P24941	CDK2	T337	P338S	338	Missense	proximal	1	no	14.126	2.861	EPSD	COSMIC	8.148	Loss
CMGC_CDK_CDK2_CDK2_ST	Q13415	ORC1	P24941	CDK2	T375	R380H	380	Missense	distal	5	no	15.014	14.985	EPSD;PhosphoSitePlus	COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	Q13415	ORC1	P24941	CDK2	T375	A372V	372	Missense	distal	-3	no	15.014	15.215	EPSD;PhosphoSitePlus	COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	Q13415	ORC1	P24941	CDK2	T375	R380C	380	Missense	distal	5	no	15.014	15.141	EPSD;PhosphoSitePlus	COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	Q13415	ORC1	P24941	CDK2	T375	A368V	368	Missense	distal	-7	no	15.014	14.869	EPSD;PhosphoSitePlus	COSMIC;GDSC;CCLE	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	Q13415	ORC1	P24941	CDK2	T375	R378S	378	Missense	distal	3	no	15.014	13.329	EPSD;PhosphoSitePlus	COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	Q13415	ORC1	P24941	CDK2	T428	E423K	423	Missense	distal	-5	no	14.917	14.882	EPSD	COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	Q13415	ORC1	P24941	CDK2	S610	T607P	607	Missense	distal	-3	no	16.736	16.775	EPSD	COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	Q13415	ORC1	P24941	CDK2	S610	T607S	607	Missense	distal	-3	no	16.736	16.871	EPSD	COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	P54132	BLM	P24941	CDK2	T57	R61I	61	Missense	distal	4	no	14.943	15.034	EPSD	COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	P54132	BLM	P24941	CDK2	T57	D64H	64	Missense	distal	7	no	14.943	14.388	EPSD	COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	P54132	BLM	P24941	CDK2	T57	V54I	54	Missense	distal	-3	no	14.943	14.820	EPSD	COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	P54132	BLM	P24941	CDK2	T114	F111V	111	Missense	distal	-3	no	13.353	13.309	EPSD	COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	P54132	BLM	P24941	CDK2	T114	P109L	109	Missense	distal	-5	no	13.353	13.365	EPSD	COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	P54132	BLM	P24941	CDK2	T114	P109S	109	Missense	distal	-5	no	13.353	13.309	EPSD	COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	P54132	BLM	P24941	CDK2	T114	V118I	118	Missense	distal	4	no	13.353	13.098	EPSD	COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	P54132	BLM	P24941	CDK2	T114	D110Y	110	Missense	distal	-4	no	13.353	13.292	EPSD	COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	P54132	BLM	P24941	CDK2	T114	P115L	115	Missense	proximal	1	no	13.353	3.533	EPSD	COSMIC	8.148	Loss
CMGC_CDK_CDK2_CDK2_ST	P54132	BLM	P24941	CDK2	T114	E117K	117	Missense	distal	3	no	13.353	15.439	EPSD	COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	P54132	BLM	P24941	CDK2	T114	L107S	107	Missense	distal	-7	no	13.353	13.168	EPSD	COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	P54132	BLM	P24941	CDK2	T125	V118I	118	Missense	distal	-7	no	14.320	14.494	EPSD	COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	P54132	BLM	P24941	CDK2	T125	P126S	126	Missense	proximal	1	no	14.320	3.054	EPSD	COSMIC	8.148	Loss
CMGC_CDK_CDK2_CDK2_ST	P54132	BLM	P24941	CDK2	T125	S131P	131	Missense	distal	6	no	14.320	14.318	EPSD	COSMIC;CCLE	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	P54132	BLM	P24941	CDK2	S144	S147F	147	Missense	distal	3	no	15.323	15.248	EPSD	COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	P54132	BLM	P24941	CDK2	S144	S144L	144	Missense	central	0	yes	15.323	0.000	EPSD	COSMIC	8.148	Loss
CMGC_CDK_CDK2_CDK2_ST	P54132	BLM	P24941	CDK2	S144	T150I	150	Missense	distal	6	no	15.323	15.315	EPSD	COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	P54132	BLM	P24941	CDK2	S144	I151M	151	Missense	distal	7	no	15.323	15.811	EPSD	COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	P54132	BLM	P24941	CDK2	T171	E164K	164	Missense	distal	-7	no	11.025	10.887	EPSD	COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	P54132	BLM	P24941	CDK2	T171	S168L	168	Missense	distal	-3	no	11.025	10.858	EPSD	COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	P54132	BLM	P24941	CDK2	T171	H176D	176	Missense	distal	5	no	11.025	11.120	EPSD	COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	P54132	BLM	P24941	CDK2	S269	K271R	271	Missense	proximal	2	no	8.035	8.335	EPSD	COSMIC	8.148	Gain
CMGC_CDK_CDK2_CDK2_ST	P54132	BLM	P24941	CDK2	S282	C288F	288	Missense	distal	6	no	9.693	9.689	EPSD	COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	P54132	BLM	P24941	CDK2	S282	P287S	287	Missense	distal	5	no	9.693	9.592	EPSD	COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	P54132	BLM	P24941	CDK2	S282	H281P	281	Missense	proximal	-1	no	9.693	9.574	EPSD	COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	P54132	BLM	P24941	CDK2	S282	C288Y	288	Missense	distal	6	no	9.693	9.699	EPSD	COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	P54132	BLM	P24941	CDK2	S304	P305S	305	Missense	proximal	1	no	12.972	1.706	EPSD	COSMIC	8.148	Loss
CMGC_CDK_CDK2_CDK2_ST	P54132	BLM	P24941	CDK2	S426	S426L	426	Missense	central	0	yes	9.048	0.000	EPSD	COSMIC	8.148	Loss
CMGC_CDK_CDK2_CDK2_ST	P54132	BLM	P24941	CDK2	T473	S480F	480	Missense	distal	7	no	8.194	9.048	EPSD	COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	P54132	BLM	P24941	CDK2	T508	R510K	510	Missense	proximal	2	no	11.924	11.624	EPSD	COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	P54132	BLM	P24941	CDK2	T508	G512E	512	Missense	distal	4	no	11.924	12.061	EPSD	COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	P54132	BLM	P24941	CDK2	T508	E507K	507	Missense	proximal	-1	no	11.924	11.039	EPSD	COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	P54132	BLM	P24941	CDK2	S579	S580P	580	Missense	proximal	1	no	1.371	12.637	EPSD	COSMIC	8.148	Gain
CMGC_CDK_CDK2_CDK2_ST	P54132	BLM	P24941	CDK2	S706	S706F	706	Missense	central	0	yes	14.649	0.000	EPSD	COSMIC	8.148	Loss
CMGC_CDK_CDK2_CDK2_ST	P54132	BLM	P24941	CDK2	S714	V721I	721	Missense	distal	7	no	14.707	14.505	EPSD	COSMIC;GDSC;CCLE	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	P54132	BLM	P24941	CDK2	T766	I770M	770	Missense	distal	4	no	16.368	15.976	EPSD	COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	P54132	BLM	P24941	CDK2	T907	M904K	904	Missense	distal	-3	no	9.347	8.938	EPSD	COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	P54132	BLM	P24941	CDK2	T907	C901Y	901	Missense	distal	-6	no	9.347	9.341	EPSD	COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	P54132	BLM	P24941	CDK2	S1290	Q1283H	1283	Missense	distal	-7	no	14.154	14.320	EPSD	COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	P54132	BLM	P24941	CDK2	S1290	S1290L	1290	Missense	central	0	yes	14.154	0.000	EPSD	COSMIC	8.148	Loss
CMGC_CDK_CDK2_CDK2_ST	P54132	BLM	P24941	CDK2	S1296	S1302F	1302	Missense	distal	6	no	13.185	13.166	EPSD	COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	P54132	BLM	P24941	CDK2	S1296	S1290L	1290	Missense	distal	-6	no	13.185	13.186	EPSD	COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	O00429	DNM1L	P24941	CDK2	S126	S119L	119	Missense	distal	-7	no	13.109	13.295	EPSD	COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	O00429	DNM1L	P24941	CDK2	S126	K133N	133	Missense	distal	7	no	13.109	13.302	EPSD	COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	O00429	DNM1L	P24941	CDK2	S126	G124E	124	Missense	proximal	-2	no	13.109	12.736	EPSD	COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	O00429	DNM1L	P24941	CDK2	S126	G124R	124	Missense	proximal	-2	no	13.109	12.616	EPSD	COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	O00429	DNM1L	P24941	CDK2	S126	G120C	120	Missense	distal	-6	no	13.109	13.112	EPSD	COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	O00429	DNM1L	P24941	CDK2	S136	K133N	133	Missense	distal	-3	no	16.362	16.424	EPSD	COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	O00429	DNM1L	P24941	CDK2	S548	A543S	543	Missense	distal	-5	no	14.167	14.098	EPSD	COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	O00429	DNM1L	P24941	CDK2	S548	Q545K	545	Missense	distal	-3	no	14.167	14.068	EPSD	COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	O00429	DNM1L	P24941	CDK2	S616	P611L	611	Missense	distal	-5	no	16.062	16.074	PhosphoSitePlus	COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	O00429	DNM1L	P24941	CDK2	S616	A622D	622	Missense	distal	6	no	16.062	16.051	PhosphoSitePlus	COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	Q8IXM2	C17orf49	P24941	CDK2	S36	D34N	34	Missense	proximal	-2	no	12.637	11.428	EPSD	COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	Q8IXM2	C17orf49	P24941	CDK2	S36	D34V	34	Missense	proximal	-2	no	12.637	12.122	EPSD	COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	Q8IXM2	C17orf49	P24941	CDK2	S96	P91L	91	Missense	distal	-5	no	15.428	15.440	PhosphoSitePlus	COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	Q8IXM2	C17orf49	P24941	CDK2	S96	I90T	90	Missense	distal	-6	no	15.428	15.426	PhosphoSitePlus	COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	Q8IXM2	C17orf49	P24941	CDK2	S110	P117L	117	Missense	distal	7	no	12.905	12.936	EPSD	COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	Q8IXM2	C17orf49	P24941	CDK2	S110	P116L	116	Missense	distal	6	no	12.905	12.907	EPSD	COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	Q8IXM2	C17orf49	P24941	CDK2	S110	A115V	115	Missense	distal	5	no	12.905	12.862	EPSD	COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	Q8IXM2	C17orf49	P24941	CDK2	S110	A114D	114	Missense	distal	4	no	12.905	12.800	EPSD	COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	Q8IXM2	C17orf49	P24941	CDK2	T161	P162S	162	Missense	proximal	1	no	13.777	2.511	EPSD	COSMIC	8.148	Loss
CMGC_CDK_CDK2_CDK2_ST	P28749	RBL1	P24941	CDK2	T332	F336L	336	Missense	distal	4	no	18.255	18.550	EPSD	COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	P28749	RBL1	P24941	CDK2	T340	P341Q	341	Missense	proximal	1	no	13.989	6.078	EPSD	COSMIC	8.148	Loss
CMGC_CDK_CDK2_CDK2_ST	P28749	RBL1	P24941	CDK2	T340	F336L	336	Missense	distal	-4	no	13.989	14.539	EPSD	COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	P28749	RBL1	P24941	CDK2	T369	R374Q	374	Missense	distal	5	no	12.875	12.729	EPSD	COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	P28749	RBL1	P24941	CDK2	T385	A382T	382	Missense	distal	-3	no	12.535	12.553	EPSD	COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	P28749	RBL1	P24941	CDK2	S615	P616S	616	Missense	proximal	1	no	17.319	6.054	EPSD	COSMIC	8.148	Loss
CMGC_CDK_CDK2_CDK2_ST	P28749	RBL1	P24941	CDK2	S615	V622F	622	Missense	distal	7	no	17.319	17.763	EPSD	COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	P28749	RBL1	P24941	CDK2	S640	P641L	641	Missense	proximal	1	no	14.260	4.439	EPSD;PhosphoSitePlus	COSMIC	8.148	Loss
CMGC_CDK_CDK2_CDK2_ST	P28749	RBL1	P24941	CDK2	S640	P641Q	641	Missense	proximal	1	no	14.260	6.348	EPSD;PhosphoSitePlus	COSMIC	8.148	Loss
CMGC_CDK_CDK2_CDK2_ST	P28749	RBL1	P24941	CDK2	S640	H645N	645	Missense	distal	5	no	14.260	14.285	EPSD;PhosphoSitePlus	COSMIC;GDSC;CCLE	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	P28749	RBL1	P24941	CDK2	S650	S649C	649	Missense	proximal	-1	no	13.655	13.999	PhosphoSitePlus;EPSD	COSMIC;GDSC;CCLE	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	P28749	RBL1	P24941	CDK2	S650	S655N	655	Missense	distal	5	no	13.655	13.859	PhosphoSitePlus;EPSD	COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	P28749	RBL1	P24941	CDK2	S650	H645N	645	Missense	distal	-5	no	13.655	13.627	PhosphoSitePlus;EPSD	COSMIC;GDSC;CCLE	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	P28749	RBL1	P24941	CDK2	S964	D959G	959	Missense	distal	-5	no	14.832	14.854	EPSD	COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	P28749	RBL1	P24941	CDK2	S964	P967S	967	Missense	distal	3	no	14.832	14.866	EPSD	COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	P28749	RBL1	P24941	CDK2	S964	P965A	965	Missense	proximal	1	no	14.832	0.429	EPSD	COSMIC	8.148	Loss
CMGC_CDK_CDK2_CDK2_ST	P28749	RBL1	P24941	CDK2	S988	S988F	988	Missense	central	0	yes	16.752	0.000	EPSD	COSMIC	8.148	Loss
CMGC_CDK_CDK2_CDK2_ST	P28749	RBL1	P24941	CDK2	S988	P989S	989	Missense	proximal	1	no	16.752	5.486	EPSD	COSMIC	8.148	Loss
CMGC_CDK_CDK2_CDK2_ST	P28749	RBL1	P24941	CDK2	S1009	P1010H	1010	Missense	proximal	1	no	17.199	10.440	EPSD	COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	P28749	RBL1	P24941	CDK2	S1009	K1005N	1005	Missense	distal	-4	no	17.199	17.418	EPSD	COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	P28749	RBL1	P24941	CDK2	S1009	G1008F	1008	Missense	proximal	-1	no	17.199	16.936	EPSD	COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	P28749	RBL1	P24941	CDK2	S1009	D1016H	1016	Missense	distal	7	no	17.199	16.644	EPSD	COSMIC;GDSC;CCLE	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	P28749	RBL1	P24941	CDK2	S1041	P1042S	1042	Missense	proximal	1	no	16.162	4.896	EPSD	COSMIC	8.148	Loss
CMGC_CDK_CDK2_CDK2_ST	P28749	RBL1	P24941	CDK2	S1041	K1044E	1044	Missense	distal	3	no	16.162	14.076	EPSD	COSMIC;GDSC;CCLE	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	P28749	RBL1	P24941	CDK2	S1041	D1038G	1038	Missense	distal	-3	no	16.162	16.200	EPSD	COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	P28749	RBL1	P24941	CDK2	S1041	P1042L	1042	Missense	proximal	1	no	16.162	6.341	EPSD	COSMIC	8.148	Loss
CMGC_CDK_CDK2_CDK2_ST	P28749	RBL1	P24941	CDK2	S1041	P1042T	1042	Missense	proximal	1	no	16.162	6.204	EPSD	COSMIC	8.148	Loss
CMGC_CDK_CDK2_CDK2_ST	P13051	UNG	P24941	CDK2	S12	A16S	16	Missense	distal	4	no	13.559	13.532	PhosphoSitePlus;EPSD	COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	P13051	UNG	P24941	CDK2	S12	R19L	19	Missense	distal	7	no	13.559	13.099	PhosphoSitePlus;EPSD	COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	P13051	UNG	P24941	CDK2	S12	P15L	15	Missense	distal	3	no	13.559	13.175	PhosphoSitePlus;EPSD	COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	P13051	UNG	P24941	CDK2	S14	A16S	16	Missense	proximal	2	no	14.457	14.498	EPSD	COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	P13051	UNG	P24941	CDK2	S14	R19L	19	Missense	distal	5	no	14.457	14.390	EPSD	COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	P13051	UNG	P24941	CDK2	S14	P15L	15	Missense	proximal	1	no	14.457	4.636	EPSD	COSMIC	8.148	Loss
CMGC_CDK_CDK2_CDK2_ST	P13051	UNG	P24941	CDK2	S23	A16S	16	Missense	distal	-7	no	13.084	12.739	EPSD;PhosphoSitePlus	COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	P13051	UNG	P24941	CDK2	S23	R19L	19	Missense	distal	-4	no	13.084	13.268	EPSD;PhosphoSitePlus	COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	P13051	UNG	P24941	CDK2	T60	P61S	61	Missense	proximal	1	no	14.936	3.670	EPSD;PhosphoSitePlus	COSMIC	8.148	Loss
CMGC_CDK_CDK2_CDK2_ST	P13051	UNG	P24941	CDK2	S64	P61S	61	Missense	distal	-3	no	12.611	12.707	EPSD;PhosphoSitePlus	COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	P13051	UNG	P24941	CDK2	S279	Q274L	274	Missense	distal	-5	no	13.966	13.978	EPSD	COSMIC;CCLE	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	P13051	UNG	P24941	CDK2	S279	L281F	281	Missense	proximal	2	no	13.966	14.324	EPSD	COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	P13051	UNG	P24941	CDK2	S279	V272G	272	Missense	distal	-7	no	13.966	14.271	EPSD	COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	P13051	UNG	P24941	CDK2	S279	H277R	277	Missense	proximal	-2	no	13.966	13.740	EPSD	COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	Q92547	TOPBP1	P24941	CDK2	S370	Y365H	365	Missense	distal	-5	no	10.388	10.411	EPSD	COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	Q92547	TOPBP1	P24941	CDK2	S370	D375Y	375	Missense	distal	5	no	10.388	10.288	EPSD	COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	Q92547	TOPBP1	P24941	CDK2	T779	P780L	780	Missense	proximal	1	no	11.270	1.449	EPSD	COSMIC	8.148	Loss
CMGC_CDK_CDK2_CDK2_ST	Q92547	TOPBP1	P24941	CDK2	T779	T776P	776	Missense	distal	-3	no	11.270	11.309	EPSD	COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	Q92547	TOPBP1	P24941	CDK2	T779	T776I	776	Missense	distal	-3	no	11.270	11.329	EPSD	COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	Q92547	TOPBP1	P24941	CDK2	T779	F786C	786	Missense	distal	7	no	11.270	11.209	EPSD	COSMIC;GDSC;CCLE	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	Q92547	TOPBP1	P24941	CDK2	S805	R800T	800	Missense	distal	-5	no	14.896	14.848	EPSD	COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	Q92547	TOPBP1	P24941	CDK2	T848	S853N	853	Missense	distal	5	no	15.210	15.414	PhosphoSitePlus	COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	Q92547	TOPBP1	P24941	CDK2	S853	R857M	857	Missense	distal	4	no	8.475	8.174	EPSD	COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	Q92547	TOPBP1	P24941	CDK2	S853	S853N	853	Missense	central	0	yes	8.475	0.000	EPSD	COSMIC	8.148	Loss
CMGC_CDK_CDK2_CDK2_ST	Q92547	TOPBP1	P24941	CDK2	T861	R857M	857	Missense	distal	-4	no	11.412	10.907	EPSD	COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	Q92547	TOPBP1	P24941	CDK2	T861	V866G	866	Missense	distal	5	no	11.412	11.572	EPSD	COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	Q92547	TOPBP1	P24941	CDK2	S1183	P1188A	1188	Missense	distal	5	no	13.212	13.222	EPSD	COSMIC;CCLE	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	Q92547	TOPBP1	P24941	CDK2	T1221	H1227R	1227	Missense	distal	6	no	17.366	17.354	EPSD	COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	Q92547	TOPBP1	P24941	CDK2	T1221	P1222S	1222	Missense	proximal	1	no	17.366	6.100	EPSD	COSMIC	8.148	Loss
CMGC_CDK_CDK2_CDK2_ST	Q92547	TOPBP1	P24941	CDK2	T1231	P1232S	1232	Missense	proximal	1	no	13.097	1.831	EPSD	COSMIC	8.148	Loss
CMGC_CDK_CDK2_CDK2_ST	Q92547	TOPBP1	P24941	CDK2	T1231	A1238V	1238	Missense	distal	7	no	13.097	12.971	EPSD	COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	Q92547	TOPBP1	P24941	CDK2	T1231	H1227R	1227	Missense	distal	-4	no	13.097	13.458	EPSD	COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	Q92785	DPF2	P24941	CDK2	S244	P247R	247	Missense	distal	3	no	7.491	9.209	EPSD	COSMIC	8.148	Gain
CMGC_CDK_CDK2_CDK2_ST	Q92785	DPF2	P24941	CDK2	T248	P247R	247	Missense	proximal	-1	no	15.200	15.771	EPSD	COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	Q92785	DPF2	P24941	CDK2	T358	Y352F	352	Missense	distal	-6	no	11.160	11.164	EPSD	COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	Q92785	DPF2	P24941	CDK2	T358	C356Y	356	Missense	proximal	-2	no	11.160	11.657	EPSD	COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	Q92785	DPF2	P24941	CDK2	T358	C356S	356	Missense	proximal	-2	no	11.160	11.570	EPSD	COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	Q9UEY8	ADD3	P24941	CDK2	T12	P19L	19	Missense	distal	7	no	13.195	13.225	EPSD	COSMIC;GDSC;CCLE	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	Q9UEY8	ADD3	P24941	CDK2	T12	V9M	9	Missense	distal	-3	no	13.195	13.420	EPSD	COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	Q9UEY8	ADD3	P24941	CDK2	T12	S17R	17	Missense	distal	5	no	13.195	13.402	EPSD	COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	Q9UEY8	ADD3	P24941	CDK2	S42	P43S	43	Missense	proximal	1	no	14.917	3.651	EPSD	COSMIC	8.148	Loss
CMGC_CDK_CDK2_CDK2_ST	Q9UEY8	ADD3	P24941	CDK2	S64	R68Q	68	Missense	distal	4	no	13.449	13.630	EPSD	COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	Q9UEY8	ADD3	P24941	CDK2	S108	L111R	111	Missense	distal	3	no	11.625	13.726	EPSD	COSMIC;GDSC;CCLE	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	Q9UEY8	ADD3	P24941	CDK2	S108	S112N	112	Missense	distal	4	no	11.625	11.591	EPSD	COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	Q9UEY8	ADD3	P24941	CDK2	T117	L111R	111	Missense	distal	-6	no	13.273	13.275	EPSD	COSMIC;GDSC;CCLE	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	Q9UEY8	ADD3	P24941	CDK2	T117	S112N	112	Missense	distal	-5	no	13.273	13.336	EPSD	COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	Q9UEY8	ADD3	P24941	CDK2	S351	G354V	354	Missense	distal	3	no	7.686	8.395	EPSD	COSMIC	8.148	Gain
CMGC_CDK_CDK2_CDK2_ST	Q9UEY8	ADD3	P24941	CDK2	S360	G367V	367	Missense	distal	7	no	11.189	10.778	EPSD	COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	Q9UEY8	ADD3	P24941	CDK2	S360	S360F	360	Missense	central	0	yes	11.189	0.000	EPSD	COSMIC	8.148	Loss
CMGC_CDK_CDK2_CDK2_ST	Q9UEY8	ADD3	P24941	CDK2	S360	K365N	365	Missense	distal	5	no	11.189	11.346	EPSD	COSMIC;GDSC;CCLE	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	Q9UEY8	ADD3	P24941	CDK2	S360	G359S	359	Missense	proximal	-1	no	11.189	9.670	EPSD	COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	Q9UEY8	ADD3	P24941	CDK2	S402	E405K	405	Missense	distal	3	no	7.315	9.401	EPSD	COSMIC	8.148	Gain
CMGC_CDK_CDK2_CDK2_ST	Q9UEY8	ADD3	P24941	CDK2	S423	A429T	429	Missense	distal	6	no	17.772	17.783	PhosphoSitePlus	COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	Q9UEY8	ADD3	P24941	CDK2	S442	T437R	437	Missense	distal	-5	no	15.579	15.628	EPSD	COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	Q9UEY8	ADD3	P24941	CDK2	S461	R456W	456	Missense	distal	-5	no	13.088	13.175	EPSD	COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	Q9UEY8	ADD3	P24941	CDK2	S461	G458R	458	Missense	distal	-3	no	13.088	13.173	EPSD	COSMIC;CCLE	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	Q9UEY8	ADD3	P24941	CDK2	S461	G458E	458	Missense	distal	-3	no	13.088	13.159	EPSD	COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	Q9UEY8	ADD3	P24941	CDK2	T481	P488S	488	Missense	distal	7	no	15.493	15.341	EPSD	COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	Q9UEY8	ADD3	P24941	CDK2	S664	T661N	661	Missense	distal	-3	no	14.352	14.413	EPSD	COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	Q9UEY8	ADD3	P24941	CDK2	S677	S681L	681	Missense	distal	4	no	15.279	15.378	EPSD	COSMIC;CCLE	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	Q9UEY8	ADD3	P24941	CDK2	S677	P682S	682	Missense	distal	5	no	15.279	15.178	EPSD	COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	Q9UEY8	ADD3	P24941	CDK2	S681	S681L	681	Missense	central	0	yes	16.946	0.000	EPSD	COSMIC;CCLE	8.148	Loss
CMGC_CDK_CDK2_CDK2_ST	Q9UEY8	ADD3	P24941	CDK2	S681	P682S	682	Missense	proximal	1	no	16.946	5.680	EPSD	COSMIC	8.148	Loss
CMGC_CDK_CDK2_CDK2_ST	Q9UEY8	ADD3	P24941	CDK2	T691	R690H	690	Missense	proximal	-1	no	14.131	13.679	EPSD	COSMIC;GDSC;CCLE	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	Q9UEY8	ADD3	P24941	CDK2	T691	N698K	698	Missense	distal	7	no	14.131	13.938	EPSD	COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	Q9UEY8	ADD3	P24941	CDK2	T691	F689V	689	Missense	proximal	-2	no	14.131	14.594	EPSD	COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	Q0VD86	INCA1	P24941	CDK2	S23	R18S	18	Missense	distal	-5	no	14.291	14.200	EPSD;PhosphoSitePlus	COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	Q0VD86	INCA1	P24941	CDK2	S23	P25H	25	Missense	proximal	2	no	14.291	14.369	EPSD;PhosphoSitePlus	COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	Q0VD86	INCA1	P24941	CDK2	S23	R22Q	22	Missense	proximal	-1	no	14.291	13.413	EPSD;PhosphoSitePlus	COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	Q0VD86	INCA1	P24941	CDK2	S191	S194Y	194	Missense	distal	3	no	13.226	12.447	PhosphoSitePlus;EPSD	COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	Q0VD86	INCA1	P24941	CDK2	S194	S194Y	194	Missense	central	0	yes	11.992	0.000	EPSD	COSMIC	8.148	Loss
CMGC_CDK_CDK2_CDK2_ST	P61978	HNRNPK	P24941	CDK2	S82	E85K	85	Missense	distal	3	no	6.673	8.759	EPSD	COSMIC	8.148	Gain
CMGC_CDK_CDK2_CDK2_ST	P61978	HNRNPK	P24941	CDK2	S116	L123P	123	Missense	distal	7	no	14.915	14.884	EPSD	COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	P61978	HNRNPK	P24941	CDK2	S116	T118A	118	Missense	proximal	2	no	14.915	15.117	EPSD	COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	P61978	HNRNPK	P24941	CDK2	S284	M283T	283	Missense	proximal	-1	no	18.787	17.474	PhosphoSitePlus;EPSD	COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	P61978	HNRNPK	P24941	CDK2	S302	G297C	297	Missense	distal	-5	no	8.160	8.161	EPSD	COSMIC;CCLE	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	P61978	HNRNPK	P24941	CDK2	S302	R299W	299	Missense	distal	-3	no	8.160	8.241	EPSD	COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	P61978	HNRNPK	P24941	CDK2	S302	G298V	298	Missense	distal	-4	no	8.160	8.430	EPSD	COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	P61978	HNRNPK	P24941	CDK2	S302	G295R	295	Missense	distal	-7	no	8.160	8.179	EPSD	COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	P25098	GRK2	P24941	CDK2	T263	T263M	263	Missense	central	0	yes	16.568	0.000	EPSD	COSMIC	8.148	Loss
CMGC_CDK_CDK2_CDK2_ST	P25098	GRK2	P24941	CDK2	T263	F261L	261	Missense	proximal	-2	no	16.568	17.456	EPSD	COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	P25098	GRK2	P24941	CDK2	T263	D265E	265	Missense	proximal	2	no	16.568	16.667	EPSD	COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	P25098	GRK2	P24941	CDK2	T353	M357K	357	Missense	distal	4	no	7.578	8.401	EPSD	COSMIC	8.148	Gain
CMGC_CDK_CDK2_CDK2_ST	P25098	GRK2	P24941	CDK2	T353	A349D	349	Missense	distal	-4	no	7.578	8.164	EPSD	COSMIC	8.148	Gain
CMGC_CDK_CDK2_CDK2_ST	P25098	GRK2	P24941	CDK2	S389	R386W	386	Missense	distal	-3	no	17.367	17.448	EPSD	COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	P25098	GRK2	P24941	CDK2	S389	G387R	387	Missense	proximal	-2	no	17.367	16.873	EPSD	COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	P25098	GRK2	P24941	CDK2	S670	V672M	672	Missense	proximal	2	no	14.993	15.081	PhosphoSitePlus	COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	P25098	GRK2	P24941	CDK2	S670	V672L	672	Missense	proximal	2	no	14.993	14.763	PhosphoSitePlus	COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	P25098	GRK2	P24941	CDK2	S670	P668S	668	Missense	proximal	-2	no	14.993	14.341	PhosphoSitePlus	COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	O00311	CDC7	P24941	CDK2	S16	Q18K	18	Missense	proximal	2	no	15.438	15.237	EPSD	COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	O00311	CDC7	P24941	CDK2	T376	G375C	375	Missense	proximal	-1	no	12.843	11.668	PhosphoSitePlus	COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	O00311	CDC7	P24941	CDK2	T376	P372S	372	Missense	distal	-4	no	12.843	13.198	PhosphoSitePlus	COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	O00311	CDC7	P24941	CDK2	T472	T476P	476	Missense	distal	4	no	12.177	11.894	EPSD	COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	O00311	CDC7	P24941	CDK2	T472	M468V	468	Missense	distal	-4	no	12.177	12.877	EPSD	COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	P24941	CDK2	P24941	CDK2	T39	E42K	42	Missense	distal	3	no	6.701	8.786	EPSD	COSMIC	8.148	Gain
CMGC_CDK_CDK2_CDK2_ST	P24941	CDK2	P24941	CDK2	T41	P45L	45	Missense	distal	4	no	8.067	8.179	EPSD	COSMIC	8.148	Gain
CMGC_CDK_CDK2_CDK2_ST	P24941	CDK2	P24941	CDK2	T160	P155S	155	Missense	distal	-5	no	12.187	12.142	PhosphoSitePlus	COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	P24941	CDK2	P24941	CDK2	T160	V164L	164	Missense	distal	4	no	12.187	12.072	PhosphoSitePlus	COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	P24941	CDK2	P24941	CDK2	T221	R217W	217	Missense	distal	-4	no	15.212	14.454	EPSD	COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	P24941	CDK2	P24941	CDK2	T221	R217L	217	Missense	distal	-4	no	15.212	15.397	EPSD	COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	P24941	CDK2	P24941	CDK2	T221	V226M	226	Missense	distal	5	no	15.212	15.553	EPSD	COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	P24941	CDK2	P24941	CDK2	T221	R214W	214	Missense	distal	-7	no	15.212	15.382	EPSD	COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	Q14980	NUMA1	P24941	CDK2	S77	P78S	78	Missense	proximal	1	no	10.824	-0.442	EPSD	COSMIC	8.148	Loss
CMGC_CDK_CDK2_CDK2_ST	Q14980	NUMA1	P24941	CDK2	S77	P78L	78	Missense	proximal	1	no	10.824	1.003	EPSD	COSMIC	8.148	Loss
CMGC_CDK_CDK2_CDK2_ST	Q14980	NUMA1	P24941	CDK2	S77	L81Q	81	Missense	distal	4	no	10.824	10.773	EPSD	COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	Q14980	NUMA1	P24941	CDK2	S112	W116S	116	Missense	distal	4	no	11.332	11.826	EPSD	COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	Q14980	NUMA1	P24941	CDK2	S112	P113H	113	Missense	proximal	1	no	11.332	4.574	EPSD	COSMIC	8.148	Loss
CMGC_CDK_CDK2_CDK2_ST	Q14980	NUMA1	P24941	CDK2	S271	K276R	276	Missense	distal	5	no	13.707	13.867	EPSD	COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	Q14980	NUMA1	P24941	CDK2	S1183	A1184P	1184	Missense	proximal	1	no	-3.176	11.227	EPSD	COSMIC	8.148	Gain
CMGC_CDK_CDK2_CDK2_ST	Q14980	NUMA1	P24941	CDK2	T1733	T1738S	1738	Missense	distal	5	no	11.679	11.604	EPSD	COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	Q14980	NUMA1	P24941	CDK2	S1757	P1758H	1758	Missense	proximal	1	no	11.817	5.059	EPSD	COSMIC	8.148	Loss
CMGC_CDK_CDK2_CDK2_ST	Q14980	NUMA1	P24941	CDK2	S1757	L1763P	1763	Missense	distal	6	no	11.817	11.816	EPSD	COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	Q14980	NUMA1	P24941	CDK2	T1776	P1777L	1777	Missense	proximal	1	no	14.456	4.636	PhosphoSitePlus	COSMIC	8.148	Loss
CMGC_CDK_CDK2_CDK2_ST	Q14980	NUMA1	P24941	CDK2	S1782	A1784D	1784	Missense	proximal	2	no	9.100	9.072	EPSD	COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	Q14980	NUMA1	P24941	CDK2	S1782	P1777L	1777	Missense	distal	-5	no	9.100	9.112	EPSD	COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	Q14980	NUMA1	P24941	CDK2	S1782	P1785T	1785	Missense	distal	3	no	9.100	8.986	EPSD	COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	Q14980	NUMA1	P24941	CDK2	S1782	T1776S	1776	Missense	distal	-6	no	9.100	9.099	EPSD	COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	Q14980	NUMA1	P24941	CDK2	S1800	S1800W	1800	Missense	central	0	yes	11.818	0.000	EPSD	COSMIC	8.148	Loss
CMGC_CDK_CDK2_CDK2_ST	Q14980	NUMA1	P24941	CDK2	S1800	R1802H	1802	Missense	proximal	2	no	11.818	11.737	EPSD	COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	Q14980	NUMA1	P24941	CDK2	S1800	L1798P	1798	Missense	proximal	-2	no	11.818	12.042	EPSD	COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	Q14980	NUMA1	P24941	CDK2	S1800	F1797L	1797	Missense	distal	-3	no	11.818	11.560	EPSD	COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	Q14980	NUMA1	P24941	CDK2	S1800	S1800L	1800	Missense	central	0	yes	11.818	0.000	EPSD	COSMIC	8.148	Loss
CMGC_CDK_CDK2_CDK2_ST	Q14980	NUMA1	P24941	CDK2	S1800	R1802C	1802	Missense	proximal	2	no	11.818	11.805	EPSD	COSMIC;GDSC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	Q14980	NUMA1	P24941	CDK2	S1862	S1856R	1856	Missense	distal	-6	no	14.132	14.134	EPSD	COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	Q14980	NUMA1	P24941	CDK2	S1862	L1857V	1857	Missense	distal	-5	no	14.132	14.151	EPSD	COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	Q14980	NUMA1	P24941	CDK2	T2000	G1999R	1999	Missense	proximal	-1	no	13.794	13.316	EPSD	COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	Q14980	NUMA1	P24941	CDK2	T2000	G1999E	1999	Missense	proximal	-1	no	13.794	13.531	EPSD	COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	Q14980	NUMA1	P24941	CDK2	T2015	T2015I	2015	Missense	central	0	yes	12.993	0.000	EPSD	COSMIC	8.148	Loss
CMGC_CDK_CDK2_CDK2_ST	Q14980	NUMA1	P24941	CDK2	T2015	R2017Q	2017	Missense	proximal	2	no	12.993	12.894	EPSD	COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	Q14980	NUMA1	P24941	CDK2	T2055	K2057E	2057	Missense	proximal	2	no	14.354	14.591	EPSD	COSMIC;GDSC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	Q14980	NUMA1	P24941	CDK2	T2055	S2062N	2062	Missense	distal	7	no	14.354	14.412	EPSD	COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	Q14980	NUMA1	P24941	CDK2	S2077	R2081H	2081	Missense	distal	4	no	11.730	11.613	EPSD	COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	Q14980	NUMA1	P24941	CDK2	S2077	P2078L	2078	Missense	proximal	1	no	11.730	1.909	EPSD	COSMIC	8.148	Loss
CMGC_CDK_CDK2_CDK2_ST	Q14980	NUMA1	P24941	CDK2	S2077	T2084P	2084	Missense	distal	7	no	11.730	12.034	EPSD	COSMIC;GDSC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	Q14980	NUMA1	P24941	CDK2	S2077	T2080P	2080	Missense	distal	3	no	11.730	11.844	EPSD	COSMIC;GDSC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	Q14980	NUMA1	P24941	CDK2	S2077	A2072V	2072	Missense	distal	-5	no	11.730	11.736	EPSD	COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	Q14980	NUMA1	P24941	CDK2	S2087	A2091V	2091	Missense	distal	4	no	12.911	13.098	EPSD	COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	Q14980	NUMA1	P24941	CDK2	S2087	R2081H	2081	Missense	distal	-6	no	12.911	12.912	EPSD	COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	Q14980	NUMA1	P24941	CDK2	S2087	T2084P	2084	Missense	distal	-3	no	12.911	12.950	EPSD	COSMIC;GDSC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	Q14980	NUMA1	P24941	CDK2	S2087	T2080P	2080	Missense	distal	-7	no	12.911	12.913	EPSD	COSMIC;GDSC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	Q14980	NUMA1	P24941	CDK2	S2087	P2088L	2088	Missense	proximal	1	no	12.911	3.090	EPSD	COSMIC	8.148	Loss
CMGC_CDK_CDK2_CDK2_ST	Q14980	NUMA1	P24941	CDK2	S2087	R2086H	2086	Missense	proximal	-1	no	12.911	12.459	EPSD	COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	Q14980	NUMA1	P24941	CDK2	S2087	R2085C	2085	Missense	proximal	-2	no	12.911	13.085	EPSD	COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	Q14980	NUMA1	P24941	CDK2	S2087	A2091T	2091	Missense	distal	4	no	12.911	13.153	EPSD	COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	Q15717	ELAVL1	P24941	CDK2	S202	R206W	206	Missense	distal	4	no	15.691	15.331	PhosphoSitePlus	COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	Q15717	ELAVL1	P24941	CDK2	S202	G208R	208	Missense	distal	6	no	15.691	15.685	PhosphoSitePlus	COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	Q15717	ELAVL1	P24941	CDK2	S202	G208V	208	Missense	distal	6	no	15.691	15.700	PhosphoSitePlus	COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	Q15717	ELAVL1	P24941	CDK2	S202	L195F	195	Missense	distal	-7	no	15.691	16.056	PhosphoSitePlus	COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	Q15717	ELAVL1	P24941	CDK2	S221	V225I	225	Missense	distal	4	no	13.732	13.477	EPSD	COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	P24864	CCNE1	P24941	CDK2	T77	D79N	79	Missense	proximal	2	no	17.699	17.632	EPSD	COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	P24864	CCNE1	P24941	CDK2	T77	P71S	71	Missense	distal	-6	no	17.699	17.698	EPSD	COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	P24864	CCNE1	P24941	CDK2	T77	P76L	76	Missense	proximal	-1	no	17.699	17.520	EPSD	COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	P24864	CCNE1	P24941	CDK2	S90	R95Q	95	Missense	distal	5	no	8.750	8.604	EPSD	COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	P24864	CCNE1	P24941	CDK2	S90	R85L	85	Missense	distal	-5	no	8.750	8.715	EPSD	COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	P24864	CCNE1	P24941	CDK2	S90	R95W	95	Missense	distal	5	no	8.750	8.917	EPSD	COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	P24864	CCNE1	P24941	CDK2	S103	V107L	107	Missense	distal	4	no	16.109	15.994	EPSD	COSMIC;CCLE	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	P24864	CCNE1	P24941	CDK2	S387	L389F	389	Missense	proximal	2	no	13.244	13.602	EPSD;PhosphoSitePlus	COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	P24864	CCNE1	P24941	CDK2	S387	S381C	381	Missense	distal	-6	no	13.244	13.250	EPSD;PhosphoSitePlus	COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	P24864	CCNE1	P24941	CDK2	S387	S391R	391	Missense	distal	4	no	13.244	13.111	EPSD;PhosphoSitePlus	COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	P24864	CCNE1	P24941	CDK2	S387	A386V	386	Missense	proximal	-1	no	13.244	13.471	EPSD;PhosphoSitePlus	COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	P24864	CCNE1	P24941	CDK2	S387	N384K	384	Missense	distal	-3	no	13.244	13.183	EPSD;PhosphoSitePlus	COSMIC;GDSC;CCLE	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	P24864	CCNE1	P24941	CDK2	T395	L389F	389	Missense	distal	-6	no	13.881	13.885	PhosphoSitePlus;EPSD	COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	P24864	CCNE1	P24941	CDK2	T395	S391R	391	Missense	distal	-4	no	13.881	13.284	PhosphoSitePlus;EPSD	COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	P24864	CCNE1	P24941	CDK2	T395	T395P	395	Missense	central	0	yes	13.881	0.000	PhosphoSitePlus;EPSD	COSMIC	8.148	Loss
CMGC_CDK_CDK2_CDK2_ST	P24864	CCNE1	P24941	CDK2	S399	T395P	395	Missense	distal	-4	no	10.890	10.723	EPSD;PhosphoSitePlus	COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	P24864	CCNE1	P24941	CDK2	S399	Q403H	403	Missense	distal	4	no	10.890	10.591	EPSD;PhosphoSitePlus	COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	Q14103	HNRNPD	P24941	CDK2	S83	S87F	87	Missense	distal	4	no	14.213	14.017	EPSD	COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	Q14103	HNRNPD	P24941	CDK2	S190	P194H	194	Missense	distal	4	no	12.015	11.777	EPSD	COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	Q14103	HNRNPD	P24941	CDK2	S190	F185L	185	Missense	distal	-5	no	12.015	11.954	EPSD	COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	Q14103	HNRNPD	P24941	CDK2	S190	G187V	187	Missense	distal	-3	no	12.015	12.054	EPSD	COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	Q14103	HNRNPD	P24941	CDK2	T193	P194H	194	Missense	proximal	1	no	15.027	8.268	PhosphoSitePlus	COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	Q14103	HNRNPD	P24941	CDK2	T193	G187V	187	Missense	distal	-6	no	15.027	15.026	PhosphoSitePlus	COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	P31350	RRM2	P24941	CDK2	T56	Q53H	53	Missense	distal	-3	no	8.630	8.718	EPSD	COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	P31350	RRM2	P24941	CDK2	T56	A63S	63	Missense	distal	7	no	8.630	8.094	EPSD	COSMIC	8.148	Loss
CMGC_CDK_CDK2_CDK2_ST	P16949	STMN1	P24941	CDK2	S25	Q18E	18	Missense	distal	-7	no	14.872	15.005	PhosphoSitePlus;EPSD	COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	P16949	STMN1	P24941	CDK2	S38	D44N	44	Missense	distal	6	no	17.348	17.367	EPSD;PhosphoSitePlus	COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	P16949	STMN1	P24941	CDK2	S38	P36L	36	Missense	proximal	-2	no	17.348	17.124	EPSD;PhosphoSitePlus	COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	P12956	XRCC6	P24941	CDK2	S27	D29N	29	Missense	proximal	2	no	9.004	8.937	EPSD	COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	P12956	XRCC6	P24941	CDK2	S27	G28E	28	Missense	proximal	1	no	9.004	7.151	EPSD	COSMIC;GDSC	8.148	Loss
CMGC_CDK_CDK2_CDK2_ST	P12956	XRCC6	P24941	CDK2	S33	D29N	29	Missense	distal	-4	no	9.069	8.681	EPSD	COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	P12956	XRCC6	P24941	CDK2	S33	G28E	28	Missense	distal	-5	no	9.069	9.027	EPSD	COSMIC;GDSC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	P12956	XRCC6	P24941	CDK2	T58	Q65K	65	Missense	distal	7	no	10.563	10.431	EPSD	COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	P12956	XRCC6	P24941	CDK2	S319	L312M	312	Missense	distal	-7	no	7.818	8.314	EPSD	COSMIC	8.148	Gain
CMGC_CDK_CDK2_CDK2_ST	P12956	XRCC6	P24941	CDK2	T428	D421N	421	Missense	distal	-7	no	13.162	12.840	EPSD	COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	P12956	XRCC6	P24941	CDK2	T428	K424I	424	Missense	distal	-4	no	13.162	13.092	EPSD	COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	P12956	XRCC6	P24941	CDK2	T428	V427M	427	Missense	proximal	-1	no	13.162	14.255	EPSD	COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	P12956	XRCC6	P24941	CDK2	T455	E450K	450	Missense	distal	-5	no	13.191	13.157	PhosphoSitePlus	COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	P12956	XRCC6	P24941	CDK2	S550	R554W	554	Missense	distal	4	no	10.327	9.967	EPSD	COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	P12956	XRCC6	P24941	CDK2	S550	D546N	546	Missense	distal	-4	no	10.327	9.938	EPSD	COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	P12956	XRCC6	P24941	CDK2	S550	R543K	543	Missense	distal	-7	no	10.327	9.936	EPSD	COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	P12956	XRCC6	P24941	CDK2	S592	S592N	592	Missense	central	0	yes	11.485	0.000	EPSD	COSMIC	8.148	Loss
CMGC_CDK_CDK2_CDK2_ST	P52948	NUP98	P24941	CDK2	S231	G229E	229	Missense	proximal	-2	no	11.843	11.470	EPSD	COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	P52948	NUP98	P24941	CDK2	S511	S507I	507	Missense	distal	-4	no	13.088	12.582	EPSD	COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	P52948	NUP98	P24941	CDK2	S511	N506Y	506	Missense	distal	-5	no	13.088	13.093	EPSD	COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	P52948	NUP98	P24941	CDK2	S511	Y510H	510	Missense	proximal	-1	no	13.088	12.768	EPSD	COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	P52948	NUP98	P24941	CDK2	S511	Y510F	510	Missense	proximal	-1	no	13.088	13.434	EPSD	COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	P52948	NUP98	P24941	CDK2	S516	F519L	519	Missense	distal	3	no	14.195	13.852	EPSD	COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	P52948	NUP98	P24941	CDK2	S516	Y510H	510	Missense	distal	-6	no	14.195	14.198	EPSD	COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	P52948	NUP98	P24941	CDK2	S516	P522L	522	Missense	distal	6	no	14.195	14.196	EPSD	COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	P52948	NUP98	P24941	CDK2	S516	Y510F	510	Missense	distal	-6	no	14.195	14.199	EPSD	COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	P52948	NUP98	P24941	CDK2	S516	R520W	520	Missense	distal	4	no	14.195	13.835	EPSD	COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	P52948	NUP98	P24941	CDK2	S524	F519L	519	Missense	distal	-5	no	9.542	9.482	EPSD	COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	P52948	NUP98	P24941	CDK2	S524	P522L	522	Missense	proximal	-2	no	9.542	9.318	EPSD	COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	P52948	NUP98	P24941	CDK2	S524	R520W	520	Missense	distal	-4	no	9.542	8.785	EPSD	COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	P52948	NUP98	P24941	CDK2	T546	L552R	552	Missense	distal	6	no	13.032	13.015	EPSD	COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	P52948	NUP98	P24941	CDK2	T546	A539V	539	Missense	distal	-7	no	13.032	12.887	EPSD	COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	P52948	NUP98	P24941	CDK2	T546	T553K	553	Missense	distal	7	no	13.032	13.050	EPSD	COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	P52948	NUP98	P24941	CDK2	T548	R555H	555	Missense	distal	7	no	9.465	9.106	EPSD	COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	P52948	NUP98	P24941	CDK2	T548	R555P	555	Missense	distal	7	no	9.465	8.975	EPSD	COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	P52948	NUP98	P24941	CDK2	T548	L552R	552	Missense	distal	4	no	9.465	9.232	EPSD	COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	P52948	NUP98	P24941	CDK2	T548	T553K	553	Missense	distal	5	no	9.465	9.436	EPSD	COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	P52948	NUP98	P24941	CDK2	T553	R555H	555	Missense	proximal	2	no	13.777	13.696	EPSD	COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	P52948	NUP98	P24941	CDK2	T553	R555P	555	Missense	proximal	2	no	13.777	13.619	EPSD	COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	P52948	NUP98	P24941	CDK2	T553	L552R	552	Missense	proximal	-1	no	13.777	14.527	EPSD	COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	P52948	NUP98	P24941	CDK2	T553	P556L	556	Missense	distal	3	no	13.777	13.394	EPSD	COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	P52948	NUP98	P24941	CDK2	T553	T553K	553	Missense	central	0	yes	13.777	0.000	EPSD	COSMIC	8.148	Loss
CMGC_CDK_CDK2_CDK2_ST	P52948	NUP98	P24941	CDK2	S612	D617N	617	Missense	distal	5	no	15.460	15.389	PhosphoSitePlus	COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	P52948	NUP98	P24941	CDK2	S612	R616C	616	Missense	distal	4	no	15.460	14.833	PhosphoSitePlus	COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	P52948	NUP98	P24941	CDK2	S612	N606S	606	Missense	distal	-6	no	15.460	15.459	PhosphoSitePlus	COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	P52948	NUP98	P24941	CDK2	S612	L610V	610	Missense	proximal	-2	no	15.460	15.034	PhosphoSitePlus	COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	P52948	NUP98	P24941	CDK2	S612	N606I	606	Missense	distal	-6	no	15.460	15.462	PhosphoSitePlus	COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	P52948	NUP98	P24941	CDK2	S612	R616K	616	Missense	distal	4	no	15.460	15.982	PhosphoSitePlus	COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	P52948	NUP98	P24941	CDK2	S623	D617N	617	Missense	distal	-6	no	14.223	14.224	EPSD	COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	P52948	NUP98	P24941	CDK2	S623	R616C	616	Missense	distal	-7	no	14.223	14.150	EPSD	COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	P52948	NUP98	P24941	CDK2	S623	E626G	626	Missense	distal	3	no	14.223	13.500	EPSD	COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	P52948	NUP98	P24941	CDK2	S623	R616K	616	Missense	distal	-7	no	14.223	13.832	EPSD	COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	P52948	NUP98	P24941	CDK2	T670	P666L	666	Missense	distal	-4	no	12.902	12.844	EPSD	COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	P52948	NUP98	P24941	CDK2	T670	I667F	667	Missense	distal	-3	no	12.902	13.069	EPSD	COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	P52948	NUP98	P24941	CDK2	T670	P668S	668	Missense	proximal	-2	no	12.902	12.251	EPSD	COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	P52948	NUP98	P24941	CDK2	T670	Q669E	669	Missense	proximal	-1	no	12.902	13.994	EPSD	COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	P52948	NUP98	P24941	CDK2	S839	A844S	844	Missense	distal	5	no	15.080	14.969	EPSD	COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	P52948	NUP98	P24941	CDK2	S839	R842C	842	Missense	distal	3	no	15.080	8.716	EPSD	COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	P52948	NUP98	P24941	CDK2	S839	R842H	842	Missense	distal	3	no	15.080	14.383	EPSD	COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	P52948	NUP98	P24941	CDK2	S839	R834S	834	Missense	distal	-5	no	15.080	14.988	EPSD	COSMIC;GDSC;CCLE	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	P52948	NUP98	P24941	CDK2	S878	H879R	879	Missense	proximal	1	no	9.661	6.621	EPSD	COSMIC	8.148	Loss
CMGC_CDK_CDK2_CDK2_ST	P52948	NUP98	P24941	CDK2	S878	Y883H	883	Missense	distal	5	no	9.661	9.665	EPSD	COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	P52948	NUP98	P24941	CDK2	T916	T916M	916	Missense	central	0	yes	12.024	0.000	EPSD	COSMIC	8.148	Loss
CMGC_CDK_CDK2_CDK2_ST	P52948	NUP98	P24941	CDK2	T916	P917L	917	Missense	proximal	1	no	12.024	2.203	EPSD	COSMIC	8.148	Loss
CMGC_CDK_CDK2_CDK2_ST	P52948	NUP98	P24941	CDK2	T916	S913I	913	Missense	distal	-3	no	12.024	11.948	EPSD	COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	P52948	NUP98	P24941	CDK2	T916	A912V	912	Missense	distal	-4	no	12.024	12.035	EPSD	COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	P52948	NUP98	P24941	CDK2	S934	P929S	929	Missense	distal	-5	no	15.084	15.040	EPSD	COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	P52948	NUP98	P24941	CDK2	S934	Q939K	939	Missense	distal	5	no	15.084	15.070	EPSD	COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	P52948	NUP98	P24941	CDK2	S934	S932N	932	Missense	proximal	-2	no	15.084	14.392	EPSD	COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	P52948	NUP98	P24941	CDK2	S934	S932I	932	Missense	proximal	-2	no	15.084	15.581	EPSD	COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	P52948	NUP98	P24941	CDK2	S934	A927T	927	Missense	distal	-7	no	15.084	14.917	EPSD	COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	P52948	NUP98	P24941	CDK2	S934	Q931H	931	Missense	distal	-3	no	15.084	15.172	EPSD	COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	P52948	NUP98	P24941	CDK2	T1000	E1003K	1003	Missense	distal	3	no	8.140	10.225	EPSD	COSMIC	8.148	Gain
CMGC_CDK_CDK2_CDK2_ST	P52948	NUP98	P24941	CDK2	T1000	K995R	995	Missense	distal	-5	no	8.140	8.184	EPSD	COSMIC	8.148	Gain
CMGC_CDK_CDK2_CDK2_ST	P52948	NUP98	P24941	CDK2	S1028	I1033V	1033	Missense	distal	5	no	13.952	13.826	EPSD	COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	P52948	NUP98	P24941	CDK2	S1028	E1025K	1025	Missense	distal	-3	no	13.952	13.737	EPSD	COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	P52948	NUP98	P24941	CDK2	S1060	V1063F	1063	Missense	distal	3	no	13.929	13.280	EPSD	COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	P52948	NUP98	P24941	CDK2	S1060	L1059F	1059	Missense	proximal	-1	no	13.929	14.894	EPSD	COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	P52948	NUP98	P24941	CDK2	T1070	V1063F	1063	Missense	distal	-7	no	12.937	13.288	EPSD	COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	P52948	NUP98	P24941	CDK2	T1070	P1071L	1071	Missense	proximal	1	no	12.937	3.116	EPSD	COSMIC	8.148	Loss
CMGC_CDK_CDK2_CDK2_ST	P52948	NUP98	P24941	CDK2	T1070	P1071H	1071	Missense	proximal	1	no	12.937	6.178	EPSD	COSMIC	8.148	Loss
CMGC_CDK_CDK2_CDK2_ST	P52948	NUP98	P24941	CDK2	S1099	S1099N	1099	Missense	central	0	yes	12.400	0.000	EPSD	COSMIC	8.148	Loss
CMGC_CDK_CDK2_CDK2_ST	P52948	NUP98	P24941	CDK2	S1099	P1105R	1105	Missense	distal	6	no	12.400	12.384	EPSD	COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	P52948	NUP98	P24941	CDK2	S1099	S1099C	1099	Missense	central	0	yes	12.400	0.000	EPSD	COSMIC	8.148	Loss
CMGC_CDK_CDK2_CDK2_ST	P52948	NUP98	P24941	CDK2	S1099	V1104A	1104	Missense	distal	5	no	12.400	12.443	EPSD	COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	P52948	NUP98	P24941	CDK2	S1099	F1095C	1095	Missense	distal	-4	no	12.400	12.256	EPSD	COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	P52948	NUP98	P24941	CDK2	S1099	S1093F	1093	Missense	distal	-6	no	12.400	12.406	EPSD	COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	P52948	NUP98	P24941	CDK2	S1099	A1101V	1101	Missense	proximal	2	no	12.400	12.498	EPSD	COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	P52948	NUP98	P24941	CDK2	S1192	T1190A	1190	Missense	proximal	-2	no	18.369	18.418	EPSD	COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	P52948	NUP98	P24941	CDK2	S1192	K1195R	1195	Missense	distal	3	no	18.369	17.379	EPSD	COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	P52948	NUP98	P24941	CDK2	T1217	L1223F	1223	Missense	distal	6	no	12.791	12.772	EPSD	COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	P52948	NUP98	P24941	CDK2	T1217	M1212I	1212	Missense	distal	-5	no	12.791	12.723	EPSD	COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	P52948	NUP98	P24941	CDK2	T1315	T1315R	1315	Missense	central	0	yes	11.998	0.000	EPSD	COSMIC	8.148	Loss
CMGC_CDK_CDK2_CDK2_ST	P52948	NUP98	P24941	CDK2	T1315	S1311C	1311	Missense	distal	-4	no	11.998	10.892	EPSD	COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	P52948	NUP98	P24941	CDK2	T1315	T1315I	1315	Missense	central	0	yes	11.998	0.000	EPSD	COSMIC	8.148	Loss
CMGC_CDK_CDK2_CDK2_ST	P52948	NUP98	P24941	CDK2	S1329	Q1326K	1326	Missense	distal	-3	no	14.390	14.291	EPSD	COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	P52948	NUP98	P24941	CDK2	S1329	S1329G	1329	Missense	central	0	yes	14.390	0.000	EPSD	COSMIC	8.148	Loss
CMGC_CDK_CDK2_CDK2_ST	P52948	NUP98	P24941	CDK2	S1329	A1333V	1333	Missense	distal	4	no	14.390	14.577	EPSD	COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	P52948	NUP98	P24941	CDK2	S1329	L1324V	1324	Missense	distal	-5	no	14.390	14.409	EPSD	COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	P52948	NUP98	P24941	CDK2	S1329	P1330A	1330	Missense	proximal	1	no	14.390	-0.013	EPSD	COSMIC	8.148	Loss
CMGC_CDK_CDK2_CDK2_ST	P52948	NUP98	P24941	CDK2	S1465	L1471M	1471	Missense	distal	6	no	13.115	13.095	EPSD	COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	P52948	NUP98	P24941	CDK2	S1465	D1460E	1460	Missense	distal	-5	no	13.115	13.095	EPSD	COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	P52948	NUP98	P24941	CDK2	S1465	P1466T	1466	Missense	proximal	1	no	13.115	3.157	EPSD	COSMIC	8.148	Loss
CMGC_CDK_CDK2_CDK2_ST	P52948	NUP98	P24941	CDK2	S1465	P1468S	1468	Missense	distal	3	no	13.115	13.149	EPSD	COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	P52948	NUP98	P24941	CDK2	S1465	L1467R	1467	Missense	proximal	2	no	13.115	13.380	EPSD	COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	P52948	NUP98	P24941	CDK2	S1689	S1689Y	1689	Missense	central	0	yes	9.421	0.000	EPSD	COSMIC	8.148	Loss
CMGC_CDK_CDK2_CDK2_ST	P52948	NUP98	P24941	CDK2	S1689	L1691I	1691	Missense	proximal	2	no	9.421	9.505	EPSD	COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	P52948	NUP98	P24941	CDK2	S1689	S1689C	1689	Missense	central	0	yes	9.421	0.000	EPSD	COSMIC	8.148	Loss
CMGC_CDK_CDK2_CDK2_ST	P52948	NUP98	P24941	CDK2	S1689	E1687G	1687	Missense	proximal	-2	no	9.421	9.794	EPSD	COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	P52948	NUP98	P24941	CDK2	S1689	D1685G	1685	Missense	distal	-4	no	9.421	8.576	EPSD	COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	P52948	NUP98	P24941	CDK2	S1689	V1692F	1692	Missense	distal	3	no	9.421	8.772	EPSD	COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	P52948	NUP98	P24941	CDK2	T1772	D1766G	1766	Missense	distal	-6	no	11.634	11.638	EPSD	COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	P52948	NUP98	P24941	CDK2	T1772	V1778I	1778	Missense	distal	6	no	11.634	11.636	EPSD	COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	P52948	NUP98	P24941	CDK2	T1772	P1775H	1775	Missense	distal	3	no	11.634	12.656	EPSD	COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	P62913	RPL11	P24941	CDK2	S29	A36P	36	Missense	distal	7	no	10.080	9.695	EPSD	COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	P62913	RPL11	P24941	CDK2	S29	N23D	23	Missense	distal	-6	no	10.080	10.079	EPSD	COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	P62913	RPL11	P24941	CDK2	S29	L22M	22	Missense	distal	-7	no	10.080	10.576	EPSD	COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	P62913	RPL11	P24941	CDK2	T47	L43R	43	Missense	distal	-4	no	14.735	14.550	PhosphoSitePlus	COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	Q9C0C2	TNKS1BP1	P24941	CDK2	S14	M20I	20	Missense	distal	6	no	9.834	9.853	EPSD	COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	Q9C0C2	TNKS1BP1	P24941	CDK2	S14	S9R	9	Missense	distal	-5	no	9.834	9.926	EPSD	COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	Q9C0C2	TNKS1BP1	P24941	CDK2	T131	P133L	133	Missense	proximal	2	no	11.902	11.795	EPSD	COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	Q9C0C2	TNKS1BP1	P24941	CDK2	T131	P133S	133	Missense	proximal	2	no	11.902	11.968	EPSD	COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	Q9C0C2	TNKS1BP1	P24941	CDK2	T131	A134S	134	Missense	distal	3	no	11.902	12.448	EPSD	COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	Q9C0C2	TNKS1BP1	P24941	CDK2	S178	P171S	171	Missense	distal	-7	no	15.991	15.811	EPSD	COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	Q9C0C2	TNKS1BP1	P24941	CDK2	S178	R181L	181	Missense	distal	3	no	15.991	13.889	EPSD	COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	Q9C0C2	TNKS1BP1	P24941	CDK2	T239	E241K	241	Missense	proximal	2	no	12.977	12.739	EPSD	COSMIC;GDSC;CCLE	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	Q9C0C2	TNKS1BP1	P24941	CDK2	S287	P291S	291	Missense	distal	4	no	14.401	14.414	EPSD	COSMIC;CCLE	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	Q9C0C2	TNKS1BP1	P24941	CDK2	S297	P291S	291	Missense	distal	-6	no	8.314	8.313	EPSD	COSMIC;CCLE	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	Q9C0C2	TNKS1BP1	P24941	CDK2	T351	S348P	348	Missense	distal	-3	no	12.218	12.123	EPSD	COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	Q9C0C2	TNKS1BP1	P24941	CDK2	T351	H350Y	350	Missense	proximal	-1	no	12.218	12.538	EPSD	COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	Q9C0C2	TNKS1BP1	P24941	CDK2	S353	S348P	348	Missense	distal	-5	no	13.714	13.758	EPSD	COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	Q9C0C2	TNKS1BP1	P24941	CDK2	S353	H350Y	350	Missense	distal	-3	no	13.714	13.683	EPSD	COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	Q9C0C2	TNKS1BP1	P24941	CDK2	S369	P372A	372	Missense	distal	3	no	13.576	13.064	EPSD	COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	Q9C0C2	TNKS1BP1	P24941	CDK2	S369	P362S	362	Missense	distal	-7	no	13.576	13.396	EPSD	COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	Q9C0C2	TNKS1BP1	P24941	CDK2	S387	T386I	386	Missense	proximal	-1	no	14.619	14.865	EPSD	COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	Q9C0C2	TNKS1BP1	P24941	CDK2	S387	I392S	392	Missense	distal	5	no	14.619	14.425	EPSD	COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	Q9C0C2	TNKS1BP1	P24941	CDK2	S435	L433F	433	Missense	proximal	-2	no	14.171	13.283	EPSD	COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	Q9C0C2	TNKS1BP1	P24941	CDK2	S435	S435L	435	Missense	central	0	yes	14.171	0.000	EPSD	COSMIC	8.148	Loss
CMGC_CDK_CDK2_CDK2_ST	Q9C0C2	TNKS1BP1	P24941	CDK2	S494	V489M	489	Missense	distal	-5	no	13.077	13.153	EPSD	COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	Q9C0C2	TNKS1BP1	P24941	CDK2	S601	P604S	604	Missense	distal	3	no	14.290	14.325	EPSD	COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	Q9C0C2	TNKS1BP1	P24941	CDK2	S672	D667G	667	Missense	distal	-5	no	10.728	10.750	EPSD	COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	Q9C0C2	TNKS1BP1	P24941	CDK2	S672	S672F	672	Missense	central	0	yes	10.728	0.000	EPSD	COSMIC	8.148	Loss
CMGC_CDK_CDK2_CDK2_ST	Q9C0C2	TNKS1BP1	P24941	CDK2	S712	S712P	712	Missense	central	0	yes	15.975	0.000	EPSD	COSMIC;GDSC;CCLE	8.148	Loss
CMGC_CDK_CDK2_CDK2_ST	Q9C0C2	TNKS1BP1	P24941	CDK2	S1103	G1105E	1105	Missense	proximal	2	no	14.619	14.598	EPSD	COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	Q9C0C2	TNKS1BP1	P24941	CDK2	T1206	N1204D	1204	Missense	proximal	-2	no	6.975	8.183	EPSD	COSMIC	8.148	Gain
CMGC_CDK_CDK2_CDK2_ST	Q9C0C2	TNKS1BP1	P24941	CDK2	S1211	E1215K	1215	Missense	distal	4	no	9.185	9.569	EPSD	COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	Q9C0C2	TNKS1BP1	P24941	CDK2	S1211	G1213V	1213	Missense	proximal	2	no	9.185	9.190	EPSD	COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	Q9C0C2	TNKS1BP1	P24941	CDK2	S1211	N1204D	1204	Missense	distal	-7	no	9.185	9.507	EPSD	COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	Q9C0C2	TNKS1BP1	P24941	CDK2	S1261	G1262D	1262	Missense	proximal	1	no	10.663	9.731	EPSD	COSMIC;GDSC;CCLE	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	Q9C0C2	TNKS1BP1	P24941	CDK2	S1261	G1266E	1266	Missense	distal	5	no	10.663	10.615	EPSD	COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	Q9C0C2	TNKS1BP1	P24941	CDK2	T1282	D1280A	1280	Missense	proximal	-2	no	14.035	14.186	EPSD	COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	Q9C0C2	TNKS1BP1	P24941	CDK2	S1297	G1293W	1293	Missense	distal	-4	no	13.030	12.348	EPSD	COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	Q9C0C2	TNKS1BP1	P24941	CDK2	S1297	E1300Q	1300	Missense	distal	3	no	13.030	12.383	EPSD	COSMIC;GDSC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	Q9C0C2	TNKS1BP1	P24941	CDK2	S1297	A1294T	1294	Missense	distal	-3	no	13.030	13.049	EPSD	COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	Q9C0C2	TNKS1BP1	P24941	CDK2	S1297	E1300K	1300	Missense	distal	3	no	13.030	15.116	EPSD	COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	Q9C0C2	TNKS1BP1	P24941	CDK2	S1371	S1371R	1371	Missense	central	0	yes	9.296	0.000	EPSD	COSMIC	8.148	Loss
CMGC_CDK_CDK2_CDK2_ST	Q9C0C2	TNKS1BP1	P24941	CDK2	S1371	P1374T	1374	Missense	distal	3	no	9.296	9.182	EPSD	COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	Q9C0C2	TNKS1BP1	P24941	CDK2	S1385	A1390G	1390	Missense	distal	5	no	16.386	16.503	EPSD	COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	Q9C0C2	TNKS1BP1	P24941	CDK2	S1405	E1403D	1403	Missense	proximal	-2	no	7.695	8.676	EPSD	COSMIC	8.148	Gain
CMGC_CDK_CDK2_CDK2_ST	Q9C0C2	TNKS1BP1	P24941	CDK2	S1439	R1446H	1446	Missense	distal	7	no	16.146	15.788	EPSD	COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	Q9C0C2	TNKS1BP1	P24941	CDK2	S1503	R1501G	1501	Missense	proximal	-2	no	11.873	12.366	EPSD	COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	Q9C0C2	TNKS1BP1	P24941	CDK2	S1516	Q1517H	1517	Missense	proximal	1	no	7.637	8.790	EPSD	COSMIC	8.148	Gain
CMGC_CDK_CDK2_CDK2_ST	Q9C0C2	TNKS1BP1	P24941	CDK2	S1552	P1549S	1549	Missense	distal	-3	no	16.798	16.894	EPSD	COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	Q9C0C2	TNKS1BP1	P24941	CDK2	S1552	S1558F	1558	Missense	distal	6	no	16.798	16.779	EPSD	COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	Q14247	CTTN	P24941	CDK2	S47	S47F	47	Missense	central	0	yes	8.721	0.000	EPSD	COSMIC	8.148	Loss
CMGC_CDK_CDK2_CDK2_ST	Q14247	CTTN	P24941	CDK2	T76	G83D	83	Missense	distal	7	no	10.372	10.388	EPSD	COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	Q14247	CTTN	P24941	CDK2	T76	K70N	70	Missense	distal	-6	no	10.372	10.371	EPSD	COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	Q14247	CTTN	P24941	CDK2	T76	E71K	71	Missense	distal	-5	no	10.372	10.337	EPSD	COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	Q14247	CTTN	P24941	CDK2	T76	S81F	81	Missense	distal	5	no	10.372	10.690	EPSD	COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	Q14247	CTTN	P24941	CDK2	T401	Q394K	394	Missense	distal	-7	no	13.290	13.286	EPSD	COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	Q14247	CTTN	P24941	CDK2	T401	R396T	396	Missense	distal	-5	no	13.290	13.242	EPSD	COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	Q14247	CTTN	P24941	CDK2	S405	T411I	411	Missense	distal	6	no	14.637	14.629	PhosphoSitePlus	COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	Q14247	CTTN	P24941	CDK2	S418	T411I	411	Missense	distal	-7	no	14.847	15.044	EPSD	COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	Q14247	CTTN	P24941	CDK2	S418	V420I	420	Missense	proximal	2	no	14.847	14.702	EPSD	COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	P31749	AKT1	P24941	CDK2	T92	R86H	86	Missense	distal	-6	no	13.919	13.921	EPSD	COSMIC;GDSC;CCLE	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	P31749	AKT1	P24941	CDK2	T92	E97K	97	Missense	distal	5	no	13.919	13.786	EPSD	COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	P31749	AKT1	P24941	CDK2	T92	E91D	91	Missense	proximal	-1	no	13.919	13.890	EPSD	COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	P31749	AKT1	P24941	CDK2	T92	E91K	91	Missense	proximal	-1	no	13.919	13.034	EPSD	COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	P31749	AKT1	P24941	CDK2	T92	W99R	99	Missense	distal	7	no	13.919	13.520	EPSD	COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	P31749	AKT1	P24941	CDK2	S124	G123D	123	Missense	proximal	-1	no	11.662	11.369	EPSD	COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	P31749	AKT1	P24941	CDK2	S124	D127N	127	Missense	distal	3	no	11.662	12.913	EPSD	COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	P31749	AKT1	P24941	CDK2	S124	G130R	130	Missense	distal	6	no	11.662	11.656	EPSD	COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	P31749	AKT1	P24941	CDK2	S137	P141L	141	Missense	distal	4	no	8.832	8.944	EPSD	COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	P31749	AKT1	P24941	CDK2	S137	E133Q	133	Missense	distal	-4	no	8.832	8.383	EPSD	COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	P31749	AKT1	P24941	CDK2	S137	S137F	137	Missense	central	0	yes	8.832	0.000	EPSD	COSMIC	8.148	Loss
CMGC_CDK_CDK2_CDK2_ST	P31749	AKT1	P24941	CDK2	S137	S137Y	137	Missense	central	0	yes	8.832	0.000	EPSD	COSMIC	8.148	Loss
CMGC_CDK_CDK2_CDK2_ST	P31749	AKT1	P24941	CDK2	S137	G130R	130	Missense	distal	-7	no	8.832	8.851	EPSD	COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	P31749	AKT1	P24941	CDK2	S137	A139T	139	Missense	proximal	2	no	8.832	8.630	EPSD	COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	P31749	AKT1	P24941	CDK2	S137	E135Q	135	Missense	proximal	-2	no	8.832	9.380	EPSD	COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	P31749	AKT1	P24941	CDK2	T312	M306T	306	Missense	distal	-6	no	15.064	15.057	EPSD	COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	P31749	AKT1	P24941	CDK2	T312	M306L	306	Missense	distal	-6	no	15.064	15.057	EPSD	COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	P31749	AKT1	P24941	CDK2	T312	M306I	306	Missense	distal	-6	no	15.064	15.059	EPSD	COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	P31749	AKT1	P24941	CDK2	T312	T312I	312	Missense	central	0	yes	15.064	0.000	EPSD	COSMIC	8.148	Loss
CMGC_CDK_CDK2_CDK2_ST	P31749	AKT1	P24941	CDK2	S422	V416M	416	Missense	distal	-6	no	15.215	15.221	EPSD	COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	P31749	AKT1	P24941	CDK2	S422	S422R	422	Missense	central	0	yes	15.215	0.000	EPSD	COSMIC	8.148	Loss
CMGC_CDK_CDK2_CDK2_ST	P31749	AKT1	P24941	CDK2	T450	P452L	452	Missense	proximal	2	no	8.766	8.659	EPSD	COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	P31749	AKT1	P24941	CDK2	T450	M446I	446	Missense	distal	-4	no	8.766	9.364	EPSD	COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	P31749	AKT1	P24941	CDK2	T450	I447F	447	Missense	distal	-3	no	8.766	8.933	EPSD	COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	P31749	AKT1	P24941	CDK2	T450	T443M	443	Missense	distal	-7	no	8.766	9.270	EPSD	COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	P82970	HMGN5	P24941	CDK2	T31	V28L	28	Missense	distal	-3	no	15.847	15.633	PhosphoSitePlus	COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	P82970	HMGN5	P24941	CDK2	T31	R38I	38	Missense	distal	7	no	15.847	15.414	PhosphoSitePlus	COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	Q9H8Y8	GORASP2	P24941	CDK2	T222	P223H	223	Missense	proximal	1	no	13.618	6.859	EPSD	COSMIC	8.148	Loss
CMGC_CDK_CDK2_CDK2_ST	Q9H8Y8	GORASP2	P24941	CDK2	T222	P226S	226	Missense	distal	4	no	13.618	13.631	EPSD	COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	Q9H8Y8	GORASP2	P24941	CDK2	T222	D229N	229	Missense	distal	7	no	13.618	12.838	EPSD	COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	Q9H8Y8	GORASP2	P24941	CDK2	T225	P223H	223	Missense	proximal	-2	no	17.101	16.091	PhosphoSitePlus	COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	Q9H8Y8	GORASP2	P24941	CDK2	T225	P226S	226	Missense	proximal	1	no	17.101	5.835	PhosphoSitePlus	COSMIC	8.148	Loss
CMGC_CDK_CDK2_CDK2_ST	Q9H8Y8	GORASP2	P24941	CDK2	T225	D229N	229	Missense	distal	4	no	17.101	17.146	PhosphoSitePlus	COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	Q9H8Y8	GORASP2	P24941	CDK2	S245	S243Y	243	Missense	proximal	-2	no	13.398	13.485	EPSD	COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	Q9H8Y8	GORASP2	P24941	CDK2	S245	P241S	241	Missense	distal	-4	no	13.398	13.752	EPSD	COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	Q9H8Y8	GORASP2	P24941	CDK2	S245	I252M	252	Missense	distal	7	no	13.398	13.886	EPSD	COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	Q9H8Y8	GORASP2	P24941	CDK2	T415	P416S	416	Missense	proximal	1	no	11.553	0.287	EPSD	COSMIC	8.148	Loss
CMGC_CDK_CDK2_CDK2_ST	Q9H8Y8	GORASP2	P24941	CDK2	S451	E450V	450	Missense	proximal	-1	no	11.202	10.373	EPSD	COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	Q9H8Y8	GORASP2	P24941	CDK2	S451	A446V	446	Missense	distal	-5	no	11.202	11.208	EPSD	COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	P38919	EIF4A3	P24941	CDK2	T163	M170T	170	Missense	distal	7	no	18.812	17.963	PhosphoSitePlus	COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	P38919	EIF4A3	P24941	CDK2	T163	G156R	156	Missense	distal	-7	no	18.812	18.831	PhosphoSitePlus	COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	P38919	EIF4A3	P24941	CDK2	T163	A161S	161	Missense	proximal	-2	no	18.812	18.145	PhosphoSitePlus	COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	P38919	EIF4A3	P24941	CDK2	T163	A161T	161	Missense	proximal	-2	no	18.812	18.763	PhosphoSitePlus	COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	Q9Y253	POLH	P24941	CDK2	S396	T401S	401	Missense	distal	5	no	8.442	8.367	EPSD	COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	Q9Y253	POLH	P24941	CDK2	S687	S687N	687	Missense	central	0	yes	13.920	0.000	PhosphoSitePlus	COSMIC	8.148	Loss
CMGC_CDK_CDK2_CDK2_ST	Q9Y253	POLH	P24941	CDK2	S687	P688L	688	Missense	proximal	1	no	13.920	4.099	PhosphoSitePlus	COSMIC	8.148	Loss
CMGC_CDK_CDK2_CDK2_ST	Q9Y253	POLH	P24941	CDK2	S687	P688S	688	Missense	proximal	1	no	13.920	2.654	PhosphoSitePlus	COSMIC	8.148	Loss
CMGC_CDK_CDK2_CDK2_ST	P25054	APC	P24941	CDK2	S111	M115I	115	Missense	distal	4	no	16.473	16.865	EPSD	COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	P25054	APC	P24941	CDK2	S111	C110Y	110	Missense	proximal	-1	no	16.473	17.039	EPSD	COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	P25054	APC	P24941	CDK2	S111	S117L	117	Missense	distal	6	no	16.473	16.472	EPSD	COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	P25054	APC	P24941	CDK2	S111	S105G	105	Missense	distal	-6	no	16.473	16.476	EPSD	COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	P25054	APC	P24941	CDK2	S306	T305R	305	Missense	proximal	-1	no	8.301	9.135	EPSD	COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	P25054	APC	P24941	CDK2	S306	H307Q	307	Missense	proximal	1	no	8.301	7.148	EPSD	COSMIC	8.148	Loss
CMGC_CDK_CDK2_CDK2_ST	P25054	APC	P24941	CDK2	S306	R303K	303	Missense	distal	-3	no	8.301	8.072	EPSD	COSMIC	8.148	Loss
CMGC_CDK_CDK2_CDK2_ST	P25054	APC	P24941	CDK2	S306	P301L	301	Missense	distal	-5	no	8.301	8.313	EPSD	COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	P25054	APC	P24941	CDK2	S306	V312G	312	Missense	distal	6	no	8.301	8.292	EPSD	COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	P25054	APC	P24941	CDK2	S306	V312M	312	Missense	distal	6	no	8.301	8.284	EPSD	COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	P25054	APC	P24941	CDK2	T324	L322R	322	Missense	proximal	-2	no	10.214	9.202	EPSD	COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	P25054	APC	P24941	CDK2	T324	H325R	325	Missense	proximal	1	no	10.214	7.174	EPSD	COSMIC;CCLE	8.148	Loss
CMGC_CDK_CDK2_CDK2_ST	P25054	APC	P24941	CDK2	T324	L318V	318	Missense	distal	-6	no	10.214	10.215	EPSD	COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	P25054	APC	P24941	CDK2	T324	S317P	317	Missense	distal	-7	no	10.214	10.394	EPSD	COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	P25054	APC	P24941	CDK2	T324	S331L	331	Missense	distal	7	no	10.214	10.396	EPSD	COSMIC;GDSC;CCLE	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	P25054	APC	P24941	CDK2	T324	G323C	323	Missense	proximal	-1	no	10.214	9.038	EPSD	COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	P25054	APC	P24941	CDK2	T600	E601G	601	Missense	proximal	1	no	7.888	9.742	EPSD	COSMIC	8.148	Gain
CMGC_CDK_CDK2_CDK2_ST	P25054	APC	P24941	CDK2	T600	H598Y	598	Missense	proximal	-2	no	7.888	8.334	EPSD	COSMIC	8.148	Gain
CMGC_CDK_CDK2_CDK2_ST	P25054	APC	P24941	CDK2	S744	L749F	749	Missense	distal	5	no	16.598	16.776	EPSD	COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	P25054	APC	P24941	CDK2	S744	S744F	744	Missense	central	0	yes	16.598	0.000	EPSD	COSMIC	8.148	Loss
CMGC_CDK_CDK2_CDK2_ST	P25054	APC	P24941	CDK2	S744	P745R	745	Missense	proximal	1	no	16.598	6.799	EPSD	COSMIC	8.148	Loss
CMGC_CDK_CDK2_CDK2_ST	P25054	APC	P24941	CDK2	S744	K738E	738	Missense	distal	-6	no	16.598	16.600	EPSD	COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	P25054	APC	P24941	CDK2	S780	L779V	779	Missense	proximal	-1	no	12.949	13.086	EPSD	COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	P25054	APC	P24941	CDK2	S780	N778D	778	Missense	proximal	-2	no	12.949	14.158	EPSD	COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	P25054	APC	P24941	CDK2	S780	K782E	782	Missense	proximal	2	no	12.949	13.187	EPSD	COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	P25054	APC	P24941	CDK2	S780	D777Y	777	Missense	distal	-3	no	12.949	12.999	EPSD	COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	P25054	APC	P24941	CDK2	S780	P781L	781	Missense	proximal	1	no	12.949	3.129	EPSD	COSMIC	8.148	Loss
CMGC_CDK_CDK2_CDK2_ST	P25054	APC	P24941	CDK2	S780	N775S	775	Missense	distal	-5	no	12.949	12.886	EPSD	COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	P25054	APC	P24941	CDK2	S780	L779S	779	Missense	proximal	-1	no	12.949	12.658	EPSD	COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	P25054	APC	P24941	CDK2	S780	H785D	785	Missense	distal	5	no	12.949	13.045	EPSD	COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	P25054	APC	P24941	CDK2	S906	S905G	905	Missense	proximal	-1	no	7.014	8.533	EPSD	COSMIC	8.148	Gain
CMGC_CDK_CDK2_CDK2_ST	P25054	APC	P24941	CDK2	S908	T909P	909	Missense	proximal	1	no	7.664	17.621	EPSD	COSMIC	8.148	Gain
CMGC_CDK_CDK2_CDK2_ST	P25054	APC	P24941	CDK2	T1023	G1019A	1019	Missense	distal	-4	no	11.779	12.038	EPSD	COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	P25054	APC	P24941	CDK2	T1023	Y1027D	1027	Missense	distal	4	no	11.779	11.515	EPSD	COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	P25054	APC	P24941	CDK2	T1023	N1026K	1026	Missense	distal	3	no	11.779	15.049	EPSD	COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	P25054	APC	P24941	CDK2	T1023	L1021V	1021	Missense	proximal	-2	no	11.779	11.353	EPSD	COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	P25054	APC	P24941	CDK2	T1023	P1024A	1024	Missense	proximal	1	no	11.779	-2.625	EPSD	COSMIC	8.148	Loss
CMGC_CDK_CDK2_CDK2_ST	P25054	APC	P24941	CDK2	T1023	I1025V	1025	Missense	proximal	2	no	11.779	11.924	EPSD	COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	P25054	APC	P24941	CDK2	T1023	I1025M	1025	Missense	proximal	2	no	11.779	12.013	EPSD	COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	P25054	APC	P24941	CDK2	T1023	D1022H	1022	Missense	proximal	-1	no	11.779	11.142	EPSD	COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	P25054	APC	P24941	CDK2	T1023	K1030E	1030	Missense	distal	7	no	11.779	12.109	EPSD	COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	P25054	APC	P24941	CDK2	T1023	N1017D	1017	Missense	distal	-6	no	11.779	11.778	EPSD	COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	P25054	APC	P24941	CDK2	T1023	Y1027C	1027	Missense	distal	4	no	11.779	10.832	EPSD	COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	P25054	APC	P24941	CDK2	S1042	Q1045H	1045	Missense	distal	3	no	14.087	15.134	EPSD	COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	P25054	APC	P24941	CDK2	S1042	E1047D	1047	Missense	distal	5	no	14.087	14.182	EPSD	COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	P25054	APC	P24941	CDK2	T1082	S1081I	1081	Missense	proximal	-1	no	7.885	8.339	EPSD	COSMIC	8.148	Gain
CMGC_CDK_CDK2_CDK2_ST	P25054	APC	P24941	CDK2	S1100	P1101S	1101	Missense	proximal	1	no	16.142	4.876	EPSD	COSMIC	8.148	Loss
CMGC_CDK_CDK2_CDK2_ST	P25054	APC	P24941	CDK2	S1100	E1097Q	1097	Missense	distal	-3	no	16.142	16.025	EPSD	COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	P25054	APC	P24941	CDK2	S1100	P1101L	1101	Missense	proximal	1	no	16.142	6.321	EPSD	COSMIC	8.148	Loss
CMGC_CDK_CDK2_CDK2_ST	P25054	APC	P24941	CDK2	S1100	G1106R	1106	Missense	distal	6	no	16.142	16.137	EPSD	COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	P25054	APC	P24941	CDK2	S1100	Y1102H	1102	Missense	proximal	2	no	16.142	16.161	EPSD	COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	P25054	APC	P24941	CDK2	S1100	V1099I	1099	Missense	proximal	-1	no	16.142	16.168	EPSD	COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	P25054	APC	P24941	CDK2	S1117	N1118D	1118	Missense	proximal	1	no	-23.740	8.628	EPSD	COSMIC	8.148	Gain
CMGC_CDK_CDK2_CDK2_ST	P25054	APC	P24941	CDK2	T1220	P1221L	1221	Missense	proximal	1	no	11.148	1.328	EPSD	COSMIC	8.148	Loss
CMGC_CDK_CDK2_CDK2_ST	P25054	APC	P24941	CDK2	T1220	S1219T	1219	Missense	proximal	-1	no	11.148	11.356	EPSD	COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	P25054	APC	P24941	CDK2	T1220	P1221A	1221	Missense	proximal	1	no	11.148	-3.255	EPSD	COSMIC	8.148	Loss
CMGC_CDK_CDK2_CDK2_ST	P25054	APC	P24941	CDK2	T1220	S1213L	1213	Missense	distal	-7	no	11.148	11.334	EPSD	COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	P25054	APC	P24941	CDK2	T1220	S1223Y	1223	Missense	distal	3	no	11.148	10.369	EPSD	COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	P25054	APC	P24941	CDK2	T1267	C1270W	1270	Missense	distal	3	no	7.722	11.447	EPSD	COSMIC	8.148	Gain
CMGC_CDK_CDK2_CDK2_ST	P25054	APC	P24941	CDK2	T1267	C1263Y	1263	Missense	distal	-4	no	7.722	8.940	EPSD	COSMIC	8.148	Gain
CMGC_CDK_CDK2_CDK2_ST	P25054	APC	P24941	CDK2	T1267	C1270Y	1270	Missense	distal	3	no	7.722	11.623	EPSD	COSMIC	8.148	Gain
CMGC_CDK_CDK2_CDK2_ST	P25054	APC	P24941	CDK2	S1355	S1356P	1356	Missense	proximal	1	no	0.931	12.197	EPSD	COSMIC	8.148	Gain
CMGC_CDK_CDK2_CDK2_ST	P25054	APC	P24941	CDK2	S1356	S1355F	1355	Missense	proximal	-1	no	8.528	9.785	EPSD	COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	P25054	APC	P24941	CDK2	S1356	A1358E	1358	Missense	proximal	2	no	8.528	8.600	EPSD	COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	P25054	APC	P24941	CDK2	S1356	S1355P	1355	Missense	proximal	-1	no	8.528	8.999	EPSD	COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	P25054	APC	P24941	CDK2	S1356	P1361L	1361	Missense	distal	5	no	8.528	8.568	EPSD	COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	P25054	APC	P24941	CDK2	S1356	S1362F	1362	Missense	distal	6	no	8.528	8.509	EPSD	COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	P25054	APC	P24941	CDK2	S1356	A1358S	1358	Missense	proximal	2	no	8.528	8.570	EPSD	COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	P25054	APC	P24941	CDK2	S1356	K1363I	1363	Missense	distal	7	no	8.528	8.871	EPSD	COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	P25054	APC	P24941	CDK2	S1356	K1363E	1363	Missense	distal	7	no	8.528	8.859	EPSD	COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	P25054	APC	P24941	CDK2	S1356	V1352A	1352	Missense	distal	-4	no	8.528	8.517	EPSD	COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	P25054	APC	P24941	CDK2	S1356	H1349Y	1349	Missense	distal	-7	no	8.528	8.531	EPSD	COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	P25054	APC	P24941	CDK2	S1356	S1356P	1356	Missense	central	0	yes	8.528	0.000	EPSD	COSMIC	8.148	Loss
CMGC_CDK_CDK2_CDK2_ST	P25054	APC	P24941	CDK2	S1356	A1358T	1358	Missense	proximal	2	no	8.528	8.326	EPSD	COSMIC;GDSC;CCLE	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	P25054	APC	P24941	CDK2	S1356	V1352I	1352	Missense	distal	-4	no	8.528	8.425	EPSD	COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	P25054	APC	P24941	CDK2	S1356	F1354L	1354	Missense	proximal	-2	no	8.528	9.417	EPSD	COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	P25054	APC	P24941	CDK2	S1356	E1353D	1353	Missense	distal	-3	no	8.528	8.418	EPSD	COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	P25054	APC	P24941	CDK2	S1356	G1357R	1357	Missense	proximal	1	no	8.528	6.042	EPSD	COSMIC	8.148	Loss
CMGC_CDK_CDK2_CDK2_ST	P25054	APC	P24941	CDK2	S1356	A1351T	1351	Missense	distal	-5	no	8.528	8.502	EPSD	COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	P25054	APC	P24941	CDK2	S1356	S1355Y	1355	Missense	proximal	-1	no	8.528	9.438	EPSD	COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	P25054	APC	P24941	CDK2	S1356	G1357E	1357	Missense	proximal	1	no	8.528	6.674	EPSD	COSMIC	8.148	Loss
CMGC_CDK_CDK2_CDK2_ST	P25054	APC	P24941	CDK2	S1356	S1360F	1360	Missense	distal	4	no	8.528	8.332	EPSD	COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	P25054	APC	P24941	CDK2	S1356	E1353K	1353	Missense	distal	-3	no	8.528	8.313	EPSD	COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	P25054	APC	P24941	CDK2	S1356	K1350R	1350	Missense	distal	-6	no	8.528	8.530	EPSD	COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	P25054	APC	P24941	CDK2	S1356	E1353V	1353	Missense	distal	-3	no	8.528	8.496	EPSD	COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	P25054	APC	P24941	CDK2	S1356	G1357V	1357	Missense	proximal	1	no	8.528	-1.072	EPSD	COSMIC	8.148	Loss
CMGC_CDK_CDK2_CDK2_ST	P25054	APC	P24941	CDK2	S1360	A1366G	1366	Missense	distal	6	no	16.350	16.343	PhosphoSitePlus	COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	P25054	APC	P24941	CDK2	S1360	S1355F	1355	Missense	distal	-5	no	16.350	16.466	PhosphoSitePlus	COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	P25054	APC	P24941	CDK2	S1360	A1358E	1358	Missense	proximal	-2	no	16.350	15.218	PhosphoSitePlus	COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	P25054	APC	P24941	CDK2	S1360	S1355P	1355	Missense	distal	-5	no	16.350	16.394	PhosphoSitePlus	COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	P25054	APC	P24941	CDK2	S1360	P1361L	1361	Missense	proximal	1	no	16.350	6.529	PhosphoSitePlus	COSMIC	8.148	Loss
CMGC_CDK_CDK2_CDK2_ST	P25054	APC	P24941	CDK2	S1360	S1362F	1362	Missense	proximal	2	no	16.350	16.534	PhosphoSitePlus	COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	P25054	APC	P24941	CDK2	S1360	S1364R	1364	Missense	distal	4	no	16.350	16.216	PhosphoSitePlus	COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	P25054	APC	P24941	CDK2	S1360	A1358S	1358	Missense	proximal	-2	no	16.350	15.682	PhosphoSitePlus	COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	P25054	APC	P24941	CDK2	S1360	K1363I	1363	Missense	distal	3	no	16.350	12.974	PhosphoSitePlus	COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	P25054	APC	P24941	CDK2	S1360	K1363E	1363	Missense	distal	3	no	16.350	14.264	PhosphoSitePlus	COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	P25054	APC	P24941	CDK2	S1360	Q1367R	1367	Missense	distal	7	no	16.350	16.994	PhosphoSitePlus	COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	P25054	APC	P24941	CDK2	S1360	S1356P	1356	Missense	distal	-4	no	16.350	15.995	PhosphoSitePlus	COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	P25054	APC	P24941	CDK2	S1360	A1358T	1358	Missense	proximal	-2	no	16.350	16.300	PhosphoSitePlus	COSMIC;GDSC;CCLE	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	P25054	APC	P24941	CDK2	S1360	F1354L	1354	Missense	distal	-6	no	16.350	16.346	PhosphoSitePlus	COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	P25054	APC	P24941	CDK2	S1360	E1353D	1353	Missense	distal	-7	no	16.350	16.501	PhosphoSitePlus	COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	P25054	APC	P24941	CDK2	S1360	G1357R	1357	Missense	distal	-3	no	16.350	16.435	PhosphoSitePlus	COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	P25054	APC	P24941	CDK2	S1360	S1355Y	1355	Missense	distal	-5	no	16.350	16.418	PhosphoSitePlus	COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	P25054	APC	P24941	CDK2	S1360	G1357E	1357	Missense	distal	-3	no	16.350	16.421	PhosphoSitePlus	COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	P25054	APC	P24941	CDK2	S1360	S1360F	1360	Missense	central	0	yes	16.350	0.000	PhosphoSitePlus	COSMIC	8.148	Loss
CMGC_CDK_CDK2_CDK2_ST	P25054	APC	P24941	CDK2	S1360	E1353K	1353	Missense	distal	-7	no	16.350	16.212	PhosphoSitePlus	COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	P25054	APC	P24941	CDK2	S1360	Q1367H	1367	Missense	distal	7	no	16.350	16.636	PhosphoSitePlus	COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	P25054	APC	P24941	CDK2	S1360	E1353V	1353	Missense	distal	-7	no	16.350	16.279	PhosphoSitePlus	COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	P25054	APC	P24941	CDK2	S1360	G1365D	1365	Missense	distal	5	no	16.350	16.397	PhosphoSitePlus	COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	P25054	APC	P24941	CDK2	S1360	G1357V	1357	Missense	distal	-3	no	16.350	16.389	PhosphoSitePlus	COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	P25054	APC	P24941	CDK2	T1368	A1366G	1366	Missense	proximal	-2	no	14.571	13.812	EPSD	COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	P25054	APC	P24941	CDK2	T1368	P1361L	1361	Missense	distal	-7	no	14.571	14.576	EPSD	COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	P25054	APC	P24941	CDK2	T1368	S1362F	1362	Missense	distal	-6	no	14.571	14.576	EPSD	COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	P25054	APC	P24941	CDK2	T1368	P1373S	1373	Missense	distal	5	no	14.571	14.470	EPSD	COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	P25054	APC	P24941	CDK2	T1368	T1368I	1368	Missense	central	0	yes	14.571	0.000	EPSD	COSMIC	8.148	Loss
CMGC_CDK_CDK2_CDK2_ST	P25054	APC	P24941	CDK2	T1368	S1364R	1364	Missense	distal	-4	no	14.571	13.973	EPSD	COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	P25054	APC	P24941	CDK2	T1368	P1369H	1369	Missense	proximal	1	no	14.571	7.812	EPSD	COSMIC	8.148	Loss
CMGC_CDK_CDK2_CDK2_ST	P25054	APC	P24941	CDK2	T1368	K1363I	1363	Missense	distal	-5	no	14.571	14.607	EPSD	COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	P25054	APC	P24941	CDK2	T1368	K1363E	1363	Missense	distal	-5	no	14.571	14.605	EPSD	COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	P25054	APC	P24941	CDK2	T1368	E1374K	1374	Missense	distal	6	no	14.571	14.582	EPSD	COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	P25054	APC	P24941	CDK2	T1368	Q1367R	1367	Missense	proximal	-1	no	14.571	15.449	EPSD	COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	P25054	APC	P24941	CDK2	T1368	H1375Y	1375	Missense	distal	7	no	14.571	14.709	EPSD	COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	P25054	APC	P24941	CDK2	T1368	Q1367H	1367	Missense	proximal	-1	no	14.571	14.997	EPSD	COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	P25054	APC	P24941	CDK2	T1368	P1373T	1373	Missense	distal	5	no	14.571	14.545	EPSD	COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	P25054	APC	P24941	CDK2	T1368	P1373L	1373	Missense	distal	5	no	14.571	14.611	EPSD	COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	P25054	APC	P24941	CDK2	T1368	G1365D	1365	Missense	distal	-3	no	14.571	14.532	EPSD	COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	P25054	APC	P24941	CDK2	T1368	T1368K	1368	Missense	central	0	yes	14.571	0.000	EPSD	COSMIC	8.148	Loss
CMGC_CDK_CDK2_CDK2_ST	P25054	APC	P24941	CDK2	S1371	A1366G	1366	Missense	distal	-5	no	11.727	11.782	EPSD	COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	P25054	APC	P24941	CDK2	S1371	P1373S	1373	Missense	proximal	2	no	11.727	11.793	EPSD	COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	P25054	APC	P24941	CDK2	S1371	T1368I	1368	Missense	distal	-3	no	11.727	11.786	EPSD	COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	P25054	APC	P24941	CDK2	S1371	S1364R	1364	Missense	distal	-7	no	11.727	12.250	EPSD	COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	P25054	APC	P24941	CDK2	S1371	P1369H	1369	Missense	proximal	-2	no	11.727	10.717	EPSD	COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	P25054	APC	P24941	CDK2	S1371	E1374K	1374	Missense	distal	3	no	11.727	13.813	EPSD	COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	P25054	APC	P24941	CDK2	S1371	Q1367R	1367	Missense	distal	-4	no	11.727	11.702	EPSD	COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	P25054	APC	P24941	CDK2	S1371	H1375Y	1375	Missense	distal	4	no	11.727	12.164	EPSD	COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	P25054	APC	P24941	CDK2	S1371	Q1367H	1367	Missense	distal	-4	no	11.727	11.341	EPSD	COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	P25054	APC	P24941	CDK2	S1371	P1373T	1373	Missense	proximal	2	no	11.727	11.549	EPSD	COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	P25054	APC	P24941	CDK2	S1371	P1373L	1373	Missense	proximal	2	no	11.727	11.620	EPSD	COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	P25054	APC	P24941	CDK2	S1371	T1368S	1368	Missense	distal	-3	no	11.727	11.862	EPSD	COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	P25054	APC	P24941	CDK2	S1371	G1365D	1365	Missense	distal	-6	no	11.727	11.723	EPSD	COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	P25054	APC	P24941	CDK2	S1371	T1368K	1368	Missense	distal	-3	no	11.727	11.726	EPSD	COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	P25054	APC	P24941	CDK2	T1380	R1386S	1386	Missense	distal	6	no	13.550	13.568	EPSD	COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	P25054	APC	P24941	CDK2	T1380	S1385R	1385	Missense	distal	5	no	13.550	13.757	EPSD	COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	P25054	APC	P24941	CDK2	T1380	P1373S	1373	Missense	distal	-7	no	13.550	13.370	EPSD	COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	P25054	APC	P24941	CDK2	T1380	C1387S	1387	Missense	distal	7	no	13.550	12.757	EPSD	COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	P25054	APC	P24941	CDK2	T1380	P1381L	1381	Missense	proximal	1	no	13.550	3.729	EPSD	COSMIC	8.148	Loss
CMGC_CDK_CDK2_CDK2_ST	P25054	APC	P24941	CDK2	T1380	T1380I	1380	Missense	central	0	yes	13.550	0.000	EPSD	COSMIC	8.148	Loss
CMGC_CDK_CDK2_CDK2_ST	P25054	APC	P24941	CDK2	T1380	E1374K	1374	Missense	distal	-6	no	13.550	13.548	EPSD	COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	P25054	APC	P24941	CDK2	T1380	L1382F	1382	Missense	proximal	2	no	13.550	13.908	EPSD	COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	P25054	APC	P24941	CDK2	T1380	E1379G	1379	Missense	proximal	-1	no	13.550	13.814	EPSD	COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	P25054	APC	P24941	CDK2	T1380	H1375Y	1375	Missense	distal	-5	no	13.550	13.527	EPSD	COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	P25054	APC	P24941	CDK2	T1380	L1382P	1382	Missense	proximal	2	no	13.550	13.657	EPSD	COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	P25054	APC	P24941	CDK2	T1380	P1373T	1373	Missense	distal	-7	no	13.550	13.547	EPSD	COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	P25054	APC	P24941	CDK2	T1380	P1373L	1373	Missense	distal	-7	no	13.550	13.556	EPSD	COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	P25054	APC	P24941	CDK2	S1392	L1393P	1393	Missense	proximal	1	no	3.303	13.124	EPSD	COSMIC	8.148	Gain
CMGC_CDK_CDK2_CDK2_ST	P25054	APC	P24941	CDK2	S1426	P1432H	1432	Missense	distal	6	no	13.446	13.441	EPSD	COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	P25054	APC	P24941	CDK2	S1426	L1423F	1423	Missense	distal	-3	no	13.446	13.704	EPSD	COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	P25054	APC	P24941	CDK2	S1426	P1433L	1433	Missense	distal	7	no	13.446	13.477	EPSD	COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	P25054	APC	P24941	CDK2	S1426	D1422G	1422	Missense	distal	-4	no	13.446	12.601	EPSD	COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	P25054	APC	P24941	CDK2	S1426	M1431V	1431	Missense	distal	5	no	13.446	13.105	EPSD	COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	P25054	APC	P24941	CDK2	S1426	G1428E	1428	Missense	proximal	2	no	13.446	13.425	EPSD	COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	P25054	APC	P24941	CDK2	S1426	M1431R	1431	Missense	distal	5	no	13.446	13.245	EPSD	COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	P25054	APC	P24941	CDK2	S1426	D1422H	1422	Missense	distal	-4	no	13.446	12.315	EPSD	COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	P25054	APC	P24941	CDK2	S1426	P1427S	1427	Missense	proximal	1	no	13.446	2.180	EPSD	COSMIC	8.148	Loss
CMGC_CDK_CDK2_CDK2_ST	P25054	APC	P24941	CDK2	S1426	Q1429H	1429	Missense	distal	3	no	13.446	14.493	EPSD	COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	P25054	APC	P24941	CDK2	S1426	T1430S	1430	Missense	distal	4	no	13.446	13.177	EPSD	COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	P25054	APC	P24941	CDK2	S1426	D1425A	1425	Missense	proximal	-1	no	13.446	12.420	EPSD	COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	P25054	APC	P24941	CDK2	S1426	S1426N	1426	Missense	central	0	yes	13.446	0.000	EPSD	COSMIC	8.148	Loss
CMGC_CDK_CDK2_CDK2_ST	P25054	APC	P24941	CDK2	S1426	P1432S	1432	Missense	distal	6	no	13.446	13.447	EPSD	COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	P25054	APC	P24941	CDK2	T1438	P1432H	1432	Missense	distal	-6	no	11.310	11.313	EPSD	COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	P25054	APC	P24941	CDK2	T1438	P1440S	1440	Missense	proximal	2	no	11.310	11.376	EPSD	COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	P25054	APC	P24941	CDK2	T1438	R1435G	1435	Missense	distal	-3	no	11.310	11.225	EPSD	COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	P25054	APC	P24941	CDK2	T1438	P1433L	1433	Missense	distal	-5	no	11.310	11.322	EPSD	COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	P25054	APC	P24941	CDK2	T1438	P1441A	1441	Missense	distal	3	no	11.310	10.798	EPSD	COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	P25054	APC	P24941	CDK2	T1438	P1443L	1443	Missense	distal	5	no	11.310	11.350	EPSD	COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	P25054	APC	P24941	CDK2	T1438	M1431V	1431	Missense	distal	-7	no	11.310	10.828	EPSD	COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	P25054	APC	P24941	CDK2	T1438	S1434N	1434	Missense	distal	-4	no	11.310	11.094	EPSD	COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	P25054	APC	P24941	CDK2	T1438	P1439S	1439	Missense	proximal	1	no	11.310	0.044	EPSD	COSMIC	8.148	Loss
CMGC_CDK_CDK2_CDK2_ST	P25054	APC	P24941	CDK2	T1438	P1439L	1439	Missense	proximal	1	no	11.310	1.489	EPSD	COSMIC	8.148	Loss
CMGC_CDK_CDK2_CDK2_ST	P25054	APC	P24941	CDK2	T1438	T1438A	1438	Missense	central	0	yes	11.310	0.000	EPSD	COSMIC	8.148	Loss
CMGC_CDK_CDK2_CDK2_ST	P25054	APC	P24941	CDK2	T1438	M1431R	1431	Missense	distal	-7	no	11.310	11.152	EPSD	COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	P25054	APC	P24941	CDK2	T1438	P1442S	1442	Missense	distal	4	no	11.310	11.323	EPSD	COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	P25054	APC	P24941	CDK2	T1438	T1445I	1445	Missense	distal	7	no	11.310	11.671	EPSD	COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	P25054	APC	P24941	CDK2	T1438	S1434C	1434	Missense	distal	-4	no	11.310	10.204	EPSD	COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	P25054	APC	P24941	CDK2	T1438	P1441L	1441	Missense	distal	3	no	11.310	10.926	EPSD	COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	P25054	APC	P24941	CDK2	T1438	T1438I	1438	Missense	central	0	yes	11.310	0.000	EPSD	COSMIC	8.148	Loss
CMGC_CDK_CDK2_CDK2_ST	P25054	APC	P24941	CDK2	T1438	S1434R	1434	Missense	distal	-4	no	11.310	10.712	EPSD	COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	P25054	APC	P24941	CDK2	T1438	P1440L	1440	Missense	proximal	2	no	11.310	11.203	EPSD	COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	P25054	APC	P24941	CDK2	T1438	P1441S	1441	Missense	distal	3	no	11.310	11.344	EPSD	COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	P25054	APC	P24941	CDK2	T1438	P1432S	1432	Missense	distal	-6	no	11.310	11.309	EPSD	COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	P25054	APC	P24941	CDK2	T1438	P1443T	1443	Missense	distal	5	no	11.310	11.284	EPSD	COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	P25054	APC	P24941	CDK2	S1465	T1459N	1459	Missense	distal	-6	no	9.874	9.873	EPSD	COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	P25054	APC	P24941	CDK2	S1465	G1466E	1466	Missense	proximal	1	no	9.874	8.020	EPSD	COSMIC	8.148	Loss
CMGC_CDK_CDK2_CDK2_ST	P25054	APC	P24941	CDK2	S1465	V1472I	1472	Missense	distal	7	no	9.874	9.672	EPSD	COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	P25054	APC	P24941	CDK2	S1465	R1463S	1463	Missense	proximal	-2	no	9.874	10.458	EPSD	COSMIC;GDSC;CCLE	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	P25054	APC	P24941	CDK2	S1465	E1464G	1464	Missense	proximal	-1	no	9.874	10.137	EPSD	COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	P25054	APC	P24941	CDK2	S1465	S1465R	1465	Missense	central	0	yes	9.874	0.000	EPSD	COSMIC;CCLE	8.148	Loss
CMGC_CDK_CDK2_CDK2_ST	P25054	APC	P24941	CDK2	S1465	E1464K	1464	Missense	proximal	-1	no	9.874	8.989	EPSD	COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	P25054	APC	P24941	CDK2	S1465	Q1469L	1469	Missense	distal	4	no	9.874	9.925	EPSD	COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	P25054	APC	P24941	CDK2	S1465	K1462R	1462	Missense	distal	-3	no	9.874	10.103	EPSD	COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	P25054	APC	P24941	CDK2	S1465	R1463K	1463	Missense	proximal	-2	no	9.874	10.595	EPSD	COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	P25054	APC	P24941	CDK2	S1465	E1464V	1464	Missense	proximal	-1	no	9.874	9.046	EPSD	COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	P25054	APC	P24941	CDK2	S1465	K1462N	1462	Missense	distal	-3	no	9.874	9.935	EPSD	COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	P25054	APC	P24941	CDK2	S1465	G1466R	1466	Missense	proximal	1	no	9.874	7.387	EPSD	COSMIC	8.148	Loss
CMGC_CDK_CDK2_CDK2_ST	P25054	APC	P24941	CDK2	S1465	E1464D	1464	Missense	proximal	-1	no	9.874	9.844	EPSD	COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	P25054	APC	P24941	CDK2	S1465	P1458S	1458	Missense	distal	-7	no	9.874	9.694	EPSD	COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	P25054	APC	P24941	CDK2	S1465	R1463G	1463	Missense	proximal	-2	no	9.874	10.367	EPSD	COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	P25054	APC	P24941	CDK2	S1465	A1470T	1470	Missense	distal	5	no	9.874	9.838	EPSD	COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	P25054	APC	P24941	CDK2	S1465	A1460T	1460	Missense	distal	-5	no	9.874	9.848	EPSD	COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	P25054	APC	P24941	CDK2	S1465	A1471S	1471	Missense	distal	6	no	9.874	9.879	EPSD	COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	P25054	APC	P24941	CDK2	S1581	A1582P	1582	Missense	proximal	1	no	-1.521	12.883	EPSD	COSMIC	8.148	Gain
CMGC_CDK_CDK2_CDK2_ST	P25054	APC	P24941	CDK2	T1633	T1633I	1633	Missense	central	0	yes	13.131	0.000	EPSD	COSMIC	8.148	Loss
CMGC_CDK_CDK2_CDK2_ST	P25054	APC	P24941	CDK2	T1633	R1640Q	1640	Missense	distal	7	no	13.131	12.487	EPSD	COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	P25054	APC	P24941	CDK2	T1633	Q1627P	1627	Missense	distal	-6	no	13.131	13.128	EPSD	COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	P25054	APC	P24941	CDK2	T1633	D1637N	1637	Missense	distal	4	no	13.131	13.176	EPSD	COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	P25054	APC	P24941	CDK2	T1633	P1639S	1639	Missense	distal	6	no	13.131	13.132	EPSD	COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	P25054	APC	P24941	CDK2	T1633	D1637Y	1637	Missense	distal	4	no	13.131	13.395	EPSD	COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	P25054	APC	P24941	CDK2	T1633	P1626S	1626	Missense	distal	-7	no	13.131	12.951	EPSD	COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	P25054	APC	P24941	CDK2	T1633	R1640L	1640	Missense	distal	7	no	13.131	12.672	EPSD	COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	P25054	APC	P24941	CDK2	T1647	R1640Q	1640	Missense	distal	-7	no	12.866	12.479	EPSD	COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	P25054	APC	P24941	CDK2	T1647	S1652P	1652	Missense	distal	5	no	12.866	12.967	EPSD	COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	P25054	APC	P24941	CDK2	T1647	C1643Y	1643	Missense	distal	-4	no	12.866	14.083	EPSD	COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	P25054	APC	P24941	CDK2	T1647	P1648A	1648	Missense	proximal	1	no	12.866	-1.538	EPSD	COSMIC	8.148	Loss
CMGC_CDK_CDK2_CDK2_ST	P25054	APC	P24941	CDK2	T1647	V1641M	1641	Missense	distal	-6	no	12.866	12.871	EPSD	COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	P25054	APC	P24941	CDK2	T1647	E1645Q	1645	Missense	proximal	-2	no	12.866	13.414	EPSD	COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	P25054	APC	P24941	CDK2	T1647	R1640L	1640	Missense	distal	-7	no	12.866	12.527	EPSD	COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	P25054	APC	P24941	CDK2	S1664	A1670V	1670	Missense	distal	6	no	13.896	13.899	EPSD	COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	P25054	APC	P24941	CDK2	S1664	P1666L	1666	Missense	proximal	2	no	13.896	13.790	EPSD	COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	P25054	APC	P24941	CDK2	S1664	L1660P	1660	Missense	distal	-4	no	13.896	13.955	EPSD	COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	P25054	APC	P24941	CDK2	S1664	E1663K	1663	Missense	proximal	-1	no	13.896	13.011	EPSD	COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	P25054	APC	P24941	CDK2	S1664	L1669S	1669	Missense	distal	5	no	13.896	13.755	EPSD	COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	P25054	APC	P24941	CDK2	S1664	S1664F	1664	Missense	central	0	yes	13.896	0.000	EPSD	COSMIC	8.148	Loss
CMGC_CDK_CDK2_CDK2_ST	P25054	APC	P24941	CDK2	S1664	L1657R	1657	Missense	distal	-7	no	13.896	14.234	EPSD	COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	P25054	APC	P24941	CDK2	S1664	S1658R	1658	Missense	distal	-6	no	13.896	13.899	EPSD	COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	P25054	APC	P24941	CDK2	S1664	S1664Y	1664	Missense	central	0	yes	13.896	0.000	EPSD	COSMIC	8.148	Loss
CMGC_CDK_CDK2_CDK2_ST	P25054	APC	P24941	CDK2	S1664	P1665T	1665	Missense	proximal	1	no	13.896	3.939	EPSD	COSMIC	8.148	Loss
CMGC_CDK_CDK2_CDK2_ST	P25054	APC	P24941	CDK2	S1681	R1687Q	1687	Missense	distal	6	no	9.118	9.140	EPSD	COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	P25054	APC	P24941	CDK2	S1681	G1682D	1682	Missense	proximal	1	no	9.118	8.186	EPSD	COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	P25054	APC	P24941	CDK2	S1681	R1687G	1687	Missense	distal	6	no	9.118	9.123	EPSD	COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	P25054	APC	P24941	CDK2	S1681	E1685K	1685	Missense	distal	4	no	9.118	9.503	EPSD	COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	P25054	APC	P24941	CDK2	S1681	D1688H	1688	Missense	distal	7	no	9.118	8.563	EPSD	COSMIC;GDSC;CCLE	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	P25054	APC	P24941	CDK2	S1774	K1770N	1770	Missense	distal	-4	no	16.256	16.475	EPSD	COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	P25054	APC	P24941	CDK2	S1842	D1841H	1841	Missense	proximal	-1	no	13.113	12.476	EPSD	COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	P25054	APC	P24941	CDK2	S1842	H1845N	1845	Missense	distal	3	no	13.113	11.528	EPSD	COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	P25054	APC	P24941	CDK2	S1842	S1842L	1842	Missense	central	0	yes	13.113	0.000	EPSD	COSMIC	8.148	Loss
CMGC_CDK_CDK2_CDK2_ST	P25054	APC	P24941	CDK2	S1842	P1843S	1843	Missense	proximal	1	no	13.113	1.847	EPSD	COSMIC	8.148	Loss
CMGC_CDK_CDK2_CDK2_ST	P25054	APC	P24941	CDK2	S1842	H1845Y	1845	Missense	distal	3	no	13.113	11.345	EPSD	COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	P25054	APC	P24941	CDK2	S1842	H1845Q	1845	Missense	distal	3	no	13.113	12.066	EPSD	COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	P25054	APC	P24941	CDK2	T1847	E1850K	1850	Missense	distal	3	no	14.877	16.963	EPSD	COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	P25054	APC	P24941	CDK2	T1847	D1841H	1841	Missense	distal	-6	no	14.877	14.882	EPSD	COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	P25054	APC	P24941	CDK2	T1847	H1845N	1845	Missense	proximal	-2	no	14.877	14.544	EPSD	COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	P25054	APC	P24941	CDK2	T1847	S1842L	1842	Missense	distal	-5	no	14.877	14.933	EPSD	COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	P25054	APC	P24941	CDK2	T1847	P1843S	1843	Missense	distal	-4	no	14.877	15.232	EPSD	COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	P25054	APC	P24941	CDK2	T1847	G1851E	1851	Missense	distal	4	no	14.877	15.014	EPSD	COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	P25054	APC	P24941	CDK2	T1847	H1845Y	1845	Missense	proximal	-2	no	14.877	15.323	EPSD	COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	P25054	APC	P24941	CDK2	T1847	H1845Q	1845	Missense	proximal	-2	no	14.877	15.320	EPSD	COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	P25054	APC	P24941	CDK2	T1852	E1850K	1850	Missense	proximal	-2	no	9.471	10.072	EPSD	COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	P25054	APC	P24941	CDK2	T1852	R1858Q	1858	Missense	distal	6	no	9.471	9.493	EPSD	COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	P25054	APC	P24941	CDK2	T1852	H1845N	1845	Missense	distal	-7	no	9.471	9.266	EPSD	COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	P25054	APC	P24941	CDK2	T1852	G1851E	1851	Missense	proximal	-1	no	9.471	9.207	EPSD	COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	P25054	APC	P24941	CDK2	T1852	H1845Y	1845	Missense	distal	-7	no	9.471	9.474	EPSD	COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	P25054	APC	P24941	CDK2	T1852	S1857L	1857	Missense	distal	5	no	9.471	9.612	EPSD	COSMIC;GDSC;CCLE	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	P25054	APC	P24941	CDK2	T1852	H1845Q	1845	Missense	distal	-7	no	9.471	9.305	EPSD	COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	P25054	APC	P24941	CDK2	T1852	C1855R	1855	Missense	distal	3	no	9.471	15.835	EPSD	COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	P25054	APC	P24941	CDK2	S1864	L1865P	1865	Missense	proximal	1	no	4.061	13.882	EPSD	COSMIC	8.148	Gain
CMGC_CDK_CDK2_CDK2_ST	P25054	APC	P24941	CDK2	S1896	H1897P	1897	Missense	proximal	1	no	6.739	13.498	EPSD	COSMIC	8.148	Gain
CMGC_CDK_CDK2_CDK2_ST	P25054	APC	P24941	CDK2	T2017	R2023K	2023	Missense	distal	6	no	8.849	8.874	EPSD	COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	P25054	APC	P24941	CDK2	T2017	N2024K	2024	Missense	distal	7	no	8.849	8.656	EPSD	COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	P25054	APC	P24941	CDK2	T2017	R2023G	2023	Missense	distal	6	no	8.849	8.854	EPSD	COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	P25054	APC	P24941	CDK2	T2017	R2023I	2023	Missense	distal	6	no	8.849	8.865	EPSD	COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	P25054	APC	P24941	CDK2	T2017	P2018L	2018	Missense	proximal	1	no	8.849	-0.972	EPSD	COSMIC	8.148	Loss
CMGC_CDK_CDK2_CDK2_ST	P25054	APC	P24941	CDK2	S2054	K2050N	2050	Missense	distal	-4	no	8.459	8.678	EPSD	COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	P25054	APC	P24941	CDK2	S2054	N2060D	2060	Missense	distal	6	no	8.459	8.440	EPSD	COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	P25054	APC	P24941	CDK2	S2054	M2047V	2047	Missense	distal	-7	no	8.459	7.978	EPSD	COSMIC	8.148	Loss
CMGC_CDK_CDK2_CDK2_ST	P25054	APC	P24941	CDK2	S2054	D2059N	2059	Missense	distal	5	no	8.459	8.388	EPSD	COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	P25054	APC	P24941	CDK2	S2054	M2047I	2047	Missense	distal	-7	no	8.459	8.152	EPSD	COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	P25054	APC	P24941	CDK2	S2054	K2057R	2057	Missense	distal	3	no	8.459	7.470	EPSD	COSMIC	8.148	Loss
CMGC_CDK_CDK2_CDK2_ST	P25054	APC	P24941	CDK2	S2064	P2065L	2065	Missense	proximal	1	no	12.880	3.059	EPSD	COSMIC	8.148	Loss
CMGC_CDK_CDK2_CDK2_ST	P25054	APC	P24941	CDK2	S2064	R2066K	2066	Missense	proximal	2	no	12.880	12.580	EPSD	COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	P25054	APC	P24941	CDK2	S2064	N2060D	2060	Missense	distal	-4	no	12.880	13.269	EPSD	COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	P25054	APC	P24941	CDK2	S2064	M2068I	2068	Missense	distal	4	no	12.880	13.273	EPSD	COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	P25054	APC	P24941	CDK2	S2064	D2059N	2059	Missense	distal	-5	no	12.880	12.842	EPSD	COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	P25054	APC	P24941	CDK2	S2064	G2070A	2070	Missense	distal	6	no	12.880	12.887	EPSD	COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	P25054	APC	P24941	CDK2	S2064	G2070V	2070	Missense	distal	6	no	12.880	12.890	EPSD	COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	P25054	APC	P24941	CDK2	S2064	I2071T	2071	Missense	distal	7	no	12.880	12.519	EPSD	COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	P25054	APC	P24941	CDK2	S2064	N2067I	2067	Missense	distal	3	no	12.880	12.775	EPSD	COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	P25054	APC	P24941	CDK2	S2064	K2057R	2057	Missense	distal	-7	no	12.880	13.271	EPSD	COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	P25054	APC	P24941	CDK2	S2093	F2099C	2099	Missense	distal	6	no	12.231	12.236	EPSD	COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	P25054	APC	P24941	CDK2	S2093	P2094L	2094	Missense	proximal	1	no	12.231	2.410	EPSD	COSMIC	8.148	Loss
CMGC_CDK_CDK2_CDK2_ST	P25054	APC	P24941	CDK2	S2093	N2098S	2098	Missense	distal	5	no	12.231	12.028	EPSD	COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	P25054	APC	P24941	CDK2	S2093	S2093Y	2093	Missense	central	0	yes	12.231	0.000	EPSD	COSMIC	8.148	Loss
CMGC_CDK_CDK2_CDK2_ST	P25054	APC	P24941	CDK2	S2093	L2092I	2092	Missense	proximal	-1	no	12.231	12.394	EPSD	COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	P25054	APC	P24941	CDK2	S2146	H2149N	2149	Missense	distal	3	no	16.096	14.511	EPSD	COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	P25054	APC	P24941	CDK2	S2146	P2147A	2147	Missense	proximal	1	no	16.096	1.692	EPSD	COSMIC	8.148	Loss
CMGC_CDK_CDK2_CDK2_ST	P25054	APC	P24941	CDK2	S2146	G2145E	2145	Missense	proximal	-1	no	16.096	15.832	EPSD	COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	P25054	APC	P24941	CDK2	S2146	G2141R	2141	Missense	distal	-5	no	16.096	16.063	EPSD	COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	P25054	APC	P24941	CDK2	T2151	P2158S	2158	Missense	distal	7	no	12.566	12.414	EPSD	COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	P25054	APC	P24941	CDK2	T2151	H2149N	2149	Missense	proximal	-2	no	12.566	12.233	EPSD	COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	P25054	APC	P24941	CDK2	T2151	P2147A	2147	Missense	distal	-4	no	12.566	12.508	EPSD	COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	P25054	APC	P24941	CDK2	T2151	P2158L	2158	Missense	distal	7	no	12.566	12.597	EPSD	COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	P25054	APC	P24941	CDK2	T2151	P2158R	2158	Missense	distal	7	no	12.566	13.056	EPSD	COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	P25054	APC	P24941	CDK2	S2183	G2187E	2187	Missense	distal	4	no	8.354	8.491	EPSD	COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	P25054	APC	P24941	CDK2	S2183	G2190E	2190	Missense	distal	7	no	8.354	7.728	EPSD	COSMIC	8.148	Loss
CMGC_CDK_CDK2_CDK2_ST	P25054	APC	P24941	CDK2	S2183	T2178N	2178	Missense	distal	-5	no	8.354	8.374	EPSD	COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	P25054	APC	P24941	CDK2	S2244	S2241L	2241	Missense	distal	-3	no	13.417	13.251	EPSD	COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	P25054	APC	P24941	CDK2	S2244	V2246I	2246	Missense	proximal	2	no	13.417	13.272	EPSD	COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	P25054	APC	P24941	CDK2	S2244	S2247P	2247	Missense	distal	3	no	13.417	13.383	EPSD	COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	P25054	APC	P24941	CDK2	S2244	R2237L	2237	Missense	distal	-7	no	13.417	13.079	EPSD	COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	P25054	APC	P24941	CDK2	S2244	S2242G	2242	Missense	proximal	-2	no	13.417	13.326	EPSD	COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	P25054	APC	P24941	CDK2	S2244	K2249Q	2249	Missense	distal	5	no	13.417	13.431	EPSD	COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	P25054	APC	P24941	CDK2	T2255	L2253H	2253	Missense	proximal	-2	no	11.583	10.797	EPSD	COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	P25054	APC	P24941	CDK2	T2255	P2252H	2252	Missense	distal	-3	no	11.583	11.729	EPSD	COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	P25054	APC	P24941	CDK2	T2255	K2249Q	2249	Missense	distal	-6	no	11.583	11.586	EPSD	COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	P25054	APC	P24941	CDK2	S2260	T2266I	2266	Missense	distal	6	no	13.997	13.989	EPSD	COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	P25054	APC	P24941	CDK2	S2260	T2266S	2266	Missense	distal	6	no	13.997	13.990	EPSD	COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	P25054	APC	P24941	CDK2	S2260	L2253H	2253	Missense	distal	-7	no	13.997	14.114	EPSD	COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	P25054	APC	P24941	CDK2	S2270	T2266I	2266	Missense	distal	-4	no	11.659	11.342	EPSD	COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	P25054	APC	P24941	CDK2	S2270	T2266S	2266	Missense	distal	-4	no	11.659	11.847	EPSD	COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	P25054	APC	P24941	CDK2	S2270	T2268S	2268	Missense	proximal	-2	no	11.659	11.041	EPSD	COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	P25054	APC	P24941	CDK2	S2270	S2277F	2277	Missense	distal	7	no	11.659	12.513	EPSD	COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	P25054	APC	P24941	CDK2	S2270	A2274V	2274	Missense	distal	4	no	11.659	11.846	EPSD	COSMIC;GDSC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	P25054	APC	P24941	CDK2	S2270	S2270C	2270	Missense	central	0	yes	11.659	0.000	EPSD	COSMIC	8.148	Loss
CMGC_CDK_CDK2_CDK2_ST	P25054	APC	P24941	CDK2	S2283	V2285A	2285	Missense	proximal	2	no	10.757	10.659	EPSD	COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	P25054	APC	P24941	CDK2	S2283	S2277F	2277	Missense	distal	-6	no	10.757	10.762	EPSD	COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	P25054	APC	P24941	CDK2	S2283	A2286S	2286	Missense	distal	3	no	10.757	11.303	EPSD	COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	P25054	APC	P24941	CDK2	S2283	V2285I	2285	Missense	proximal	2	no	10.757	10.612	EPSD	COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	P25054	APC	P24941	CDK2	S2283	P2284S	2284	Missense	proximal	1	no	10.757	-0.509	EPSD	COSMIC	8.148	Loss
CMGC_CDK_CDK2_CDK2_ST	P25054	APC	P24941	CDK2	T2308	S2307T	2307	Missense	proximal	-1	no	15.857	16.065	EPSD	COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	P25054	APC	P24941	CDK2	T2308	G2303R	2303	Missense	distal	-5	no	15.857	15.825	EPSD	COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	P25054	APC	P24941	CDK2	T2308	S2302L	2302	Missense	distal	-6	no	15.857	15.858	EPSD	COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	P25054	APC	P24941	CDK2	T2308	A2313T	2313	Missense	distal	5	no	15.857	15.821	EPSD	COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	P25054	APC	P24941	CDK2	T2308	P2309L	2309	Missense	proximal	1	no	15.857	6.036	EPSD	COSMIC	8.148	Loss
CMGC_CDK_CDK2_CDK2_ST	P25054	APC	P24941	CDK2	T2308	R2311T	2311	Missense	distal	3	no	15.857	14.024	EPSD	COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	P25054	APC	P24941	CDK2	S2323	I2329V	2329	Missense	distal	6	no	14.191	14.189	EPSD	COSMIC;GDSC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	P25054	APC	P24941	CDK2	S2323	Q2322R	2322	Missense	proximal	-1	no	14.191	15.069	EPSD	COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	P25054	APC	P24941	CDK2	S2323	I2321L	2321	Missense	proximal	-2	no	14.191	14.120	EPSD	COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	P25054	APC	P24941	CDK2	S2323	R2326Q	2326	Missense	distal	3	no	14.191	12.447	EPSD	COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	P25054	APC	P24941	CDK2	S2323	P2316L	2316	Missense	distal	-7	no	14.191	14.196	EPSD	COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	P25054	APC	P24941	CDK2	S2323	P2324F	2324	Missense	proximal	1	no	14.191	-0.619	EPSD	COSMIC	8.148	Loss
CMGC_CDK_CDK2_CDK2_ST	P25054	APC	P24941	CDK2	S2330	I2329V	2329	Missense	proximal	-1	no	11.612	11.586	EPSD	COSMIC;GDSC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	P25054	APC	P24941	CDK2	S2330	R2326Q	2326	Missense	distal	-4	no	11.612	11.636	EPSD	COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	P25054	APC	P24941	CDK2	S2330	P2324F	2324	Missense	distal	-6	no	11.612	11.616	EPSD	COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	P25054	APC	P24941	CDK2	S2337	K2341N	2341	Missense	distal	4	no	12.341	11.919	EPSD	COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	P25054	APC	P24941	CDK2	S2337	Q2344E	2344	Missense	distal	7	no	12.341	12.540	EPSD	COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	P25054	APC	P24941	CDK2	S2350	S2355L	2355	Missense	distal	5	no	13.220	13.361	EPSD	COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	P25054	APC	P24941	CDK2	S2350	Q2344E	2344	Missense	distal	-6	no	13.220	13.219	EPSD	COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	P25054	APC	P24941	CDK2	S2350	T2348A	2348	Missense	proximal	-2	no	13.220	13.269	EPSD	COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	P25054	APC	P24941	CDK2	S2350	T2356I	2356	Missense	distal	6	no	13.220	13.212	EPSD	COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	P25054	APC	P24941	CDK2	S2368	Q2375L	2375	Missense	distal	7	no	16.725	16.910	EPSD	COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	P25054	APC	P24941	CDK2	S2368	Q2375R	2375	Missense	distal	7	no	16.725	17.369	EPSD	COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	P25054	APC	P24941	CDK2	S2368	Q2372P	2372	Missense	distal	4	no	16.725	16.664	EPSD	COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	P25054	APC	P24941	CDK2	S2449	A2447S	2447	Missense	proximal	-2	no	14.181	13.514	EPSD	COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	P25054	APC	P24941	CDK2	S2449	P2448L	2448	Missense	proximal	-1	no	14.181	14.002	EPSD	COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	P25054	APC	P24941	CDK2	S2449	S2449N	2449	Missense	central	0	yes	14.181	0.000	EPSD	COSMIC	8.148	Loss
CMGC_CDK_CDK2_CDK2_ST	P25054	APC	P24941	CDK2	S2449	A2447V	2447	Missense	proximal	-2	no	14.181	13.515	EPSD	COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	P25054	APC	P24941	CDK2	S2466	S2466F	2466	Missense	central	0	yes	11.045	0.000	EPSD	COSMIC	8.148	Loss
CMGC_CDK_CDK2_CDK2_ST	P25054	APC	P24941	CDK2	S2466	P2467S	2467	Missense	proximal	1	no	11.045	-0.221	EPSD	COSMIC;GDSC;CCLE	8.148	Loss
CMGC_CDK_CDK2_CDK2_ST	P25054	APC	P24941	CDK2	S2466	P2467T	2467	Missense	proximal	1	no	11.045	1.088	EPSD	COSMIC	8.148	Loss
CMGC_CDK_CDK2_CDK2_ST	P25054	APC	P24941	CDK2	S2466	R2470T	2470	Missense	distal	4	no	11.045	11.448	EPSD	COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	P25054	APC	P24941	CDK2	S2466	R2470K	2470	Missense	distal	4	no	11.045	11.567	EPSD	COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	P25054	APC	P24941	CDK2	S2466	S2466Y	2466	Missense	central	0	yes	11.045	0.000	EPSD	COSMIC	8.148	Loss
CMGC_CDK_CDK2_CDK2_ST	P25054	APC	P24941	CDK2	S2466	S2473Y	2473	Missense	distal	7	no	11.045	11.467	EPSD	COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	P25054	APC	P24941	CDK2	S2466	E2463D	2463	Missense	distal	-3	no	11.045	10.935	EPSD	COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	P25054	APC	P24941	CDK2	S2473	S2466F	2466	Missense	distal	-7	no	14.466	15.018	EPSD	COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	P25054	APC	P24941	CDK2	S2473	P2467S	2467	Missense	distal	-6	no	14.466	14.465	EPSD	COSMIC;GDSC;CCLE	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	P25054	APC	P24941	CDK2	S2473	R2470G	2470	Missense	distal	-3	no	14.466	14.381	EPSD	COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	P25054	APC	P24941	CDK2	S2473	R2470T	2470	Missense	distal	-3	no	14.466	14.238	EPSD	COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	P25054	APC	P24941	CDK2	S2473	T2475A	2475	Missense	proximal	2	no	14.466	14.668	EPSD	COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	P25054	APC	P24941	CDK2	S2473	R2470K	2470	Missense	distal	-3	no	14.466	14.237	EPSD	COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	P25054	APC	P24941	CDK2	S2473	A2479V	2479	Missense	distal	6	no	14.466	14.469	EPSD	COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	P25054	APC	P24941	CDK2	S2473	S2466Y	2466	Missense	distal	-7	no	14.466	14.772	EPSD	COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	P25054	APC	P24941	CDK2	S2473	S2473Y	2473	Missense	central	0	yes	14.466	0.000	EPSD	COSMIC	8.148	Loss
CMGC_CDK_CDK2_CDK2_ST	P25054	APC	P24941	CDK2	S2512	E2516G	2516	Missense	distal	4	no	12.667	12.531	EPSD	COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	P25054	APC	P24941	CDK2	S2512	R2505L	2505	Missense	distal	-7	no	12.667	12.329	EPSD	COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	P25054	APC	P24941	CDK2	S2512	D2519Y	2519	Missense	distal	7	no	12.667	12.250	EPSD	COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	P25054	APC	P24941	CDK2	S2512	P2508S	2508	Missense	distal	-4	no	12.667	13.022	EPSD	COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	P25054	APC	P24941	CDK2	S2531	R2530W	2530	Missense	proximal	-1	no	9.125	9.679	EPSD	COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	P25054	APC	P24941	CDK2	S2531	S2533F	2533	Missense	proximal	2	no	9.125	9.309	EPSD	COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	P25054	APC	P24941	CDK2	S2531	I2528V	2528	Missense	distal	-3	no	9.125	9.248	EPSD	COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	P25054	APC	P24941	CDK2	S2531	P2536S	2536	Missense	distal	5	no	9.125	9.024	EPSD	COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	P25054	APC	P24941	CDK2	S2531	D2527N	2527	Missense	distal	-4	no	9.125	8.736	EPSD	COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	P25054	APC	P24941	CDK2	S2531	P2536T	2536	Missense	distal	5	no	9.125	9.099	EPSD	COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	P25054	APC	P24941	CDK2	S2535	R2530W	2530	Missense	distal	-5	no	14.642	14.729	EPSD	COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	P25054	APC	P24941	CDK2	S2535	S2533F	2533	Missense	proximal	-2	no	14.642	14.180	EPSD	COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	P25054	APC	P24941	CDK2	S2535	I2528V	2528	Missense	distal	-7	no	14.642	14.467	EPSD	COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	P25054	APC	P24941	CDK2	S2535	P2536S	2536	Missense	proximal	1	no	14.642	3.376	EPSD	COSMIC	8.148	Loss
CMGC_CDK_CDK2_CDK2_ST	P25054	APC	P24941	CDK2	S2535	N2542S	2542	Missense	distal	7	no	14.642	14.583	EPSD	COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	P25054	APC	P24941	CDK2	S2535	P2536T	2536	Missense	proximal	1	no	14.642	4.684	EPSD	COSMIC	8.148	Loss
CMGC_CDK_CDK2_CDK2_ST	P25054	APC	P24941	CDK2	S2557	L2558H	2558	Missense	proximal	1	no	6.247	9.309	EPSD	COSMIC	8.148	Gain
CMGC_CDK_CDK2_CDK2_ST	P25054	APC	P24941	CDK2	S2621	Q2628H	2628	Missense	distal	7	no	11.510	11.796	EPSD	COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	P25054	APC	P24941	CDK2	S2621	S2627F	2627	Missense	distal	6	no	11.510	11.491	EPSD	COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	P25054	APC	P24941	CDK2	S2621	P2622S	2622	Missense	proximal	1	no	11.510	0.244	EPSD	COSMIC	8.148	Loss
CMGC_CDK_CDK2_CDK2_ST	P25054	APC	P24941	CDK2	S2621	S2621F	2621	Missense	central	0	yes	11.510	0.000	EPSD	COSMIC	8.148	Loss
CMGC_CDK_CDK2_CDK2_ST	P25054	APC	P24941	CDK2	S2621	P2622L	2622	Missense	proximal	1	no	11.510	1.689	EPSD	COSMIC	8.148	Loss
CMGC_CDK_CDK2_CDK2_ST	P25054	APC	P24941	CDK2	S2621	S2625N	2625	Missense	distal	4	no	11.510	11.477	EPSD	COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	P25054	APC	P24941	CDK2	S2674	R2670T	2670	Missense	distal	-4	no	10.985	11.395	EPSD	COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	P25054	APC	P24941	CDK2	S2674	N2667D	2667	Missense	distal	-7	no	10.985	11.308	EPSD	COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	P25054	APC	P24941	CDK2	S2674	S2674F	2674	Missense	central	0	yes	10.985	0.000	EPSD	COSMIC	8.148	Loss
CMGC_CDK_CDK2_CDK2_ST	P25054	APC	P24941	CDK2	S2674	R2670I	2670	Missense	distal	-4	no	10.985	11.077	EPSD	COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	P25054	APC	P24941	CDK2	T2679	S2685G	2685	Missense	distal	6	no	14.248	14.235	EPSD	COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	P25054	APC	P24941	CDK2	T2679	V2682M	2682	Missense	distal	3	no	14.248	13.399	EPSD	COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	P25054	APC	P24941	CDK2	T2679	S2674F	2674	Missense	distal	-5	no	14.248	14.364	EPSD	COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	P25054	APC	P24941	CDK2	T2760	S2766N	2766	Missense	distal	6	no	13.102	13.104	EPSD	COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	P25054	APC	P24941	CDK2	T2760	S2763N	2763	Missense	distal	3	no	13.102	12.505	EPSD	COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	P25054	APC	P24941	CDK2	T2760	T2760A	2760	Missense	central	0	yes	13.102	0.000	EPSD	COSMIC	8.148	Loss
CMGC_CDK_CDK2_CDK2_ST	P25054	APC	P24941	CDK2	T2760	S2764Y	2764	Missense	distal	4	no	13.102	13.288	EPSD	COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	P25054	APC	P24941	CDK2	S2771	S2772P	2772	Missense	proximal	1	no	3.889	15.155	EPSD	COSMIC	8.148	Gain
CMGC_CDK_CDK2_CDK2_ST	P25054	APC	P24941	CDK2	S2772	S2772P	2772	Missense	central	0	yes	10.099	0.000	EPSD	COSMIC	8.148	Loss
CMGC_CDK_CDK2_CDK2_ST	P25054	APC	P24941	CDK2	T2782	V2781A	2781	Missense	proximal	-1	no	11.635	11.408	EPSD	COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	P25054	APC	P24941	CDK2	T2782	S2789I	2789	Missense	distal	7	no	11.635	11.844	EPSD	COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	P25054	APC	P24941	CDK2	T2782	N2787S	2787	Missense	distal	5	no	11.635	11.432	EPSD	COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	P25054	APC	P24941	CDK2	T2782	V2781M	2781	Missense	proximal	-1	no	11.635	12.728	EPSD	COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	P25054	APC	P24941	CDK2	S2789	D2796N	2796	Missense	distal	7	no	17.055	16.275	EPSD	COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	P25054	APC	P24941	CDK2	S2789	P2790L	2790	Missense	proximal	1	no	17.055	7.234	EPSD	COSMIC	8.148	Loss
CMGC_CDK_CDK2_CDK2_ST	P25054	APC	P24941	CDK2	S2789	S2793G	2793	Missense	distal	4	no	17.055	16.922	EPSD	COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	P25054	APC	P24941	CDK2	S2789	S2789I	2789	Missense	central	0	yes	17.055	0.000	EPSD	COSMIC	8.148	Loss
CMGC_CDK_CDK2_CDK2_ST	P25054	APC	P24941	CDK2	S2789	N2787S	2787	Missense	proximal	-2	no	17.055	17.747	EPSD	COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	P25054	APC	P24941	CDK2	S2789	K2792R	2792	Missense	distal	3	no	17.055	16.066	EPSD	COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	P25054	APC	P24941	CDK2	S2789	D2796G	2796	Missense	distal	7	no	17.055	17.038	EPSD	COSMIC;GDSC;CCLE	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	P25054	APC	P24941	CDK2	S2789	R2791S	2791	Missense	proximal	2	no	17.055	16.963	EPSD	COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	P25054	APC	P24941	CDK2	T2807	S2803P	2803	Missense	distal	-4	no	13.457	13.102	EPSD	COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	P25054	APC	P24941	CDK2	S2830	S2825F	2825	Missense	distal	-5	no	15.826	15.943	EPSD	COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	P25054	APC	P24941	CDK2	S2830	R2833C	2833	Missense	distal	3	no	15.826	9.462	EPSD	COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	P25054	APC	P24941	CDK2	S2830	R2833H	2833	Missense	distal	3	no	15.826	15.130	EPSD	COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	P25054	APC	P24941	CDK2	S2830	G2827E	2827	Missense	distal	-3	no	15.826	15.897	EPSD	COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	P25054	APC	P24941	CDK2	S2830	E2824Q	2824	Missense	distal	-6	no	15.826	15.827	EPSD	COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	P25054	APC	P24941	CDK2	S2830	G2836V	2836	Missense	distal	6	no	15.826	15.836	EPSD	COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	Q99626	CDX2	P24941	CDK2	S283	R276K	276	Missense	distal	-7	no	15.969	15.578	PhosphoSitePlus	COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	Q99626	CDX2	P24941	CDK2	S283	L288M	288	Missense	distal	5	no	15.969	16.237	PhosphoSitePlus	COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	Q13118	KLF10	P24941	CDK2	T93	P95H	95	Missense	proximal	2	no	11.657	11.735	EPSD	COSMIC;GDSC;CCLE	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	Q13118	KLF10	P24941	CDK2	T93	S99F	99	Missense	distal	6	no	11.657	11.638	EPSD	COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	Q13118	KLF10	P24941	CDK2	S97	S104P	104	Missense	distal	7	no	13.807	13.958	EPSD	COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	Q13118	KLF10	P24941	CDK2	S97	P95H	95	Missense	proximal	-2	no	13.807	12.797	EPSD	COSMIC;GDSC;CCLE	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	Q13118	KLF10	P24941	CDK2	S97	S99F	99	Missense	proximal	2	no	13.807	13.991	EPSD	COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	Q13118	KLF10	P24941	CDK2	S206	A203T	203	Missense	distal	-3	no	14.452	14.470	PhosphoSitePlus	COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	Q13118	KLF10	P24941	CDK2	S206	C212Y	212	Missense	distal	6	no	14.452	14.457	PhosphoSitePlus	COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	Q13118	KLF10	P24941	CDK2	S206	S210Y	210	Missense	distal	4	no	14.452	14.637	PhosphoSitePlus	COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	Q13118	KLF10	P24941	CDK2	S249	S249F	249	Missense	central	0	yes	16.829	0.000	EPSD	COSMIC	8.148	Loss
CMGC_CDK_CDK2_CDK2_ST	Q13118	KLF10	P24941	CDK2	S249	P247S	247	Missense	proximal	-2	no	16.829	16.178	EPSD	COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	Q13118	KLF10	P24941	CDK2	S335	P332S	332	Missense	distal	-3	no	12.123	12.218	EPSD	COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	Q13118	KLF10	P24941	CDK2	S335	P332L	332	Missense	distal	-3	no	12.123	12.052	EPSD	COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	Q13118	KLF10	P24941	CDK2	S335	P332A	332	Missense	distal	-3	no	12.123	12.064	EPSD	COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	Q13118	KLF10	P24941	CDK2	S335	K330N	330	Missense	distal	-5	no	12.123	12.139	EPSD	COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	Q13118	KLF10	P24941	CDK2	S335	P331L	331	Missense	distal	-4	no	12.123	12.065	EPSD	COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	Q13118	KLF10	P24941	CDK2	S342	P343L	343	Missense	proximal	1	no	11.751	1.930	EPSD	COSMIC	8.148	Loss
CMGC_CDK_CDK2_CDK2_ST	Q13118	KLF10	P24941	CDK2	S342	P343S	343	Missense	proximal	1	no	11.751	0.485	EPSD	COSMIC	8.148	Loss
CMGC_CDK_CDK2_CDK2_ST	Q13118	KLF10	P24941	CDK2	T424	G425D	425	Missense	proximal	1	no	10.361	9.430	EPSD	COSMIC;GDSC;CCLE	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	Q13118	KLF10	P24941	CDK2	T424	T424K	424	Missense	central	0	yes	10.361	0.000	EPSD	COSMIC	8.148	Loss
CMGC_CDK_CDK2_CDK2_ST	Q9C0C9	UBE2O	P24941	CDK2	S99	G106V	106	Missense	distal	7	no	8.711	8.299	EPSD	COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	Q9C0C9	UBE2O	P24941	CDK2	S99	G97W	97	Missense	proximal	-2	no	8.711	7.718	EPSD	COSMIC	8.148	Loss
CMGC_CDK_CDK2_CDK2_ST	Q9C0C9	UBE2O	P24941	CDK2	S401	R408W	408	Missense	distal	7	no	15.375	15.774	EPSD	COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	Q9C0C9	UBE2O	P24941	CDK2	S401	R408Q	408	Missense	distal	7	no	15.375	14.730	EPSD	COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	Q9C0C9	UBE2O	P24941	CDK2	S401	S407F	407	Missense	distal	6	no	15.375	15.356	EPSD	COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	Q9C0C9	UBE2O	P24941	CDK2	S431	P436L	436	Missense	distal	5	no	13.497	13.537	EPSD	COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	Q9C0C9	UBE2O	P24941	CDK2	S431	A430V	430	Missense	proximal	-1	no	13.497	13.724	EPSD	COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	Q9C0C9	UBE2O	P24941	CDK2	T435	P436L	436	Missense	proximal	1	no	13.424	3.603	EPSD	COSMIC	8.148	Loss
CMGC_CDK_CDK2_CDK2_ST	Q9C0C9	UBE2O	P24941	CDK2	T435	A430V	430	Missense	distal	-5	no	13.424	13.430	EPSD	COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	Q9C0C9	UBE2O	P24941	CDK2	S441	P436L	436	Missense	distal	-5	no	14.465	14.476	EPSD	COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	Q9C0C9	UBE2O	P24941	CDK2	S836	P840A	840	Missense	distal	4	no	13.935	13.975	PhosphoSitePlus	COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	Q9C0C9	UBE2O	P24941	CDK2	S839	P840A	840	Missense	proximal	1	no	13.018	-1.385	EPSD	COSMIC	8.148	Loss
CMGC_CDK_CDK2_CDK2_ST	Q9C0C9	UBE2O	P24941	CDK2	T848	R849L	849	Missense	proximal	1	no	9.357	9.334	EPSD	COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	Q9C0C9	UBE2O	P24941	CDK2	T848	D855N	855	Missense	distal	7	no	9.357	8.577	EPSD	COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	Q9C0C9	UBE2O	P24941	CDK2	S896	P892S	892	Missense	distal	-4	no	14.068	14.422	EPSD	COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	Q9C0C9	UBE2O	P24941	CDK2	T906	C913Y	913	Missense	distal	7	no	13.623	13.252	EPSD	COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	Q9C0C9	UBE2O	P24941	CDK2	S1168	P1169S	1169	Missense	proximal	1	no	14.767	3.501	EPSD	COSMIC	8.148	Loss
CMGC_CDK_CDK2_CDK2_ST	Q9C0C9	UBE2O	P24941	CDK2	S1168	G1161R	1161	Missense	distal	-7	no	14.767	14.786	EPSD	COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	P23258	TUBG1	P24941	CDK2	T263	H267D	267	Missense	distal	4	no	14.674	14.847	EPSD	COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	P23258	TUBG1	P24941	CDK2	T263	R265Q	265	Missense	proximal	2	no	14.674	14.575	EPSD	COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	P23258	TUBG1	P24941	CDK2	T263	M270V	270	Missense	distal	7	no	14.674	14.388	EPSD	COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	P23258	TUBG1	P24941	CDK2	T274	H267D	267	Missense	distal	-7	no	11.231	11.349	EPSD	COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	P23258	TUBG1	P24941	CDK2	T274	G272D	272	Missense	proximal	-2	no	11.231	11.839	EPSD	COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	P23258	TUBG1	P24941	CDK2	T274	M270V	270	Missense	distal	-4	no	11.231	11.931	EPSD	COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	P23258	TUBG1	P24941	CDK2	T274	G272S	272	Missense	proximal	-2	no	11.231	11.322	EPSD	COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	P23258	TUBG1	P24941	CDK2	S364	P365S	365	Missense	proximal	1	no	11.482	0.216	EPSD	COSMIC	8.148	Loss
CMGC_CDK_CDK2_CDK2_ST	Q9ULW0	TPX2	P24941	CDK2	T59	L54P	54	Missense	distal	-5	no	12.983	12.971	EPSD	COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	Q9ULW0	TPX2	P24941	CDK2	S186	A180T	180	Missense	distal	-6	no	16.123	16.124	EPSD	COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	Q9ULW0	TPX2	P24941	CDK2	S293	P294S	294	Missense	proximal	1	no	15.428	4.162	EPSD	COSMIC	8.148	Loss
CMGC_CDK_CDK2_CDK2_ST	Q9ULW0	TPX2	P24941	CDK2	S293	V297A	297	Missense	distal	4	no	15.428	15.241	EPSD	COSMIC;GDSC;CCLE	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	Q9ULW0	TPX2	P24941	CDK2	S293	R296Q	296	Missense	distal	3	no	15.428	13.685	EPSD	COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	Q9ULW0	TPX2	P24941	CDK2	T338	T338I	338	Missense	central	0	yes	15.150	0.000	EPSD	COSMIC	8.148	Loss
CMGC_CDK_CDK2_CDK2_ST	Q9ULW0	TPX2	P24941	CDK2	T338	H343Y	343	Missense	distal	5	no	15.150	15.146	EPSD	COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	Q9ULW0	TPX2	P24941	CDK2	T369	P370H	370	Missense	proximal	1	no	11.771	5.013	EPSD	COSMIC;GDSC;CCLE	8.148	Loss
CMGC_CDK_CDK2_CDK2_ST	Q9ULW0	TPX2	P24941	CDK2	T369	H376Y	376	Missense	distal	7	no	11.771	11.909	EPSD	COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	Q9ULW0	TPX2	P24941	CDK2	S486	V483I	483	Missense	distal	-3	no	13.901	13.778	EPSD	COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	Q9ULW0	TPX2	P24941	CDK2	S486	V483A	483	Missense	distal	-3	no	13.901	13.700	EPSD	COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	Q9ULW0	TPX2	P24941	CDK2	S738	T743A	743	Missense	distal	5	no	17.039	17.075	EPSD	COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	O14686	KMT2D	P24941	CDK2	S48	V41F	41	Missense	distal	-7	no	14.332	14.684	EPSD	COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	O14686	KMT2D	P24941	CDK2	S48	P49H	49	Missense	proximal	1	no	14.332	7.574	EPSD	COSMIC	8.148	Loss
CMGC_CDK_CDK2_CDK2_ST	O14686	KMT2D	P24941	CDK2	S48	L44F	44	Missense	distal	-4	no	14.332	13.783	EPSD	COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	O14686	KMT2D	P24941	CDK2	S48	P55S	55	Missense	distal	7	no	14.332	14.180	EPSD	COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	O14686	KMT2D	P24941	CDK2	T54	D57N	57	Missense	distal	3	no	9.652	10.903	EPSD	COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	O14686	KMT2D	P24941	CDK2	T54	P49H	49	Missense	distal	-5	no	9.652	9.699	EPSD	COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	O14686	KMT2D	P24941	CDK2	T54	G61R	61	Missense	distal	7	no	9.652	9.472	EPSD	COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	O14686	KMT2D	P24941	CDK2	T54	P55S	55	Missense	proximal	1	no	9.652	-1.614	EPSD	COSMIC	8.148	Loss
CMGC_CDK_CDK2_CDK2_ST	O14686	KMT2D	P24941	CDK2	S98	P105S	105	Missense	distal	7	no	13.562	13.410	EPSD	COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	O14686	KMT2D	P24941	CDK2	S98	G101R	101	Missense	distal	3	no	13.562	15.382	EPSD	COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	O14686	KMT2D	P24941	CDK2	S102	E107K	107	Missense	distal	5	no	13.742	13.609	EPSD	COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	O14686	KMT2D	P24941	CDK2	S102	V109A	109	Missense	distal	7	no	13.742	13.868	EPSD	COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	O14686	KMT2D	P24941	CDK2	S102	P105S	105	Missense	distal	3	no	13.742	13.776	EPSD	COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	O14686	KMT2D	P24941	CDK2	S102	G101R	101	Missense	proximal	-1	no	13.742	13.264	EPSD	COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	O14686	KMT2D	P24941	CDK2	T366	R359C	359	Missense	distal	-7	no	11.166	11.093	EPSD	COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	O14686	KMT2D	P24941	CDK2	T366	V361F	361	Missense	distal	-5	no	11.166	11.207	EPSD	COSMIC;GDSC;CCLE	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	O14686	KMT2D	P24941	CDK2	T366	R359H	359	Missense	distal	-7	no	11.166	10.945	EPSD	COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	O14686	KMT2D	P24941	CDK2	T366	V368G	368	Missense	proximal	2	no	11.166	11.161	EPSD	COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	O14686	KMT2D	P24941	CDK2	T366	V361I	361	Missense	distal	-5	no	11.166	11.174	EPSD	COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	O14686	KMT2D	P24941	CDK2	T366	R359S	359	Missense	distal	-7	no	11.166	10.642	EPSD	COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	O14686	KMT2D	P24941	CDK2	T366	E363Q	363	Missense	distal	-3	no	11.166	11.049	EPSD	COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	O14686	KMT2D	P24941	CDK2	S373	V368G	368	Missense	distal	-5	no	16.228	16.277	EPSD	COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	O14686	KMT2D	P24941	CDK2	T380	P381F	381	Missense	proximal	1	no	9.145	-5.665	EPSD	COSMIC	8.148	Loss
CMGC_CDK_CDK2_CDK2_ST	O14686	KMT2D	P24941	CDK2	T380	E384K	384	Missense	distal	4	no	9.145	9.530	EPSD	COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	O14686	KMT2D	P24941	CDK2	T380	D386N	386	Missense	distal	6	no	9.145	9.164	EPSD	COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	O14686	KMT2D	P24941	CDK2	T380	A387D	387	Missense	distal	7	no	9.145	9.447	EPSD	COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	O14686	KMT2D	P24941	CDK2	T380	P381S	381	Missense	proximal	1	no	9.145	-2.121	EPSD	COSMIC	8.148	Loss
CMGC_CDK_CDK2_CDK2_ST	O14686	KMT2D	P24941	CDK2	S468	E463Q	463	Missense	distal	-5	no	13.541	13.504	EPSD	COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	O14686	KMT2D	P24941	CDK2	S468	L467R	467	Missense	proximal	-1	no	13.541	14.291	EPSD	COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	O14686	KMT2D	P24941	CDK2	S468	R466L	466	Missense	proximal	-2	no	13.541	14.552	EPSD	COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	O14686	KMT2D	P24941	CDK2	S468	P469L	469	Missense	proximal	1	no	13.541	3.720	EPSD	COSMIC	8.148	Loss
CMGC_CDK_CDK2_CDK2_ST	O14686	KMT2D	P24941	CDK2	S477	A476T	476	Missense	proximal	-1	no	11.570	11.577	EPSD	COSMIC;GDSC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	O14686	KMT2D	P24941	CDK2	S579	S579L	579	Missense	central	0	yes	14.706	0.000	EPSD	COSMIC	8.148	Loss
CMGC_CDK_CDK2_CDK2_ST	O14686	KMT2D	P24941	CDK2	S579	E578K	578	Missense	proximal	-1	no	14.706	13.821	EPSD	COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	O14686	KMT2D	P24941	CDK2	S579	P580A	580	Missense	proximal	1	no	14.706	0.303	EPSD	COSMIC	8.148	Loss
CMGC_CDK_CDK2_CDK2_ST	O14686	KMT2D	P24941	CDK2	S579	E577Q	577	Missense	proximal	-2	no	14.706	15.255	EPSD	COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	O14686	KMT2D	P24941	CDK2	S579	P583L	583	Missense	distal	4	no	14.706	14.818	EPSD	COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	O14686	KMT2D	P24941	CDK2	S582	S579L	579	Missense	distal	-3	no	13.351	13.185	EPSD	COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	O14686	KMT2D	P24941	CDK2	S582	E578K	578	Missense	distal	-4	no	13.351	13.040	EPSD	COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	O14686	KMT2D	P24941	CDK2	S582	P580A	580	Missense	proximal	-2	no	13.351	13.367	EPSD	COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	O14686	KMT2D	P24941	CDK2	S582	P589L	589	Missense	distal	7	no	13.351	13.382	EPSD	COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	O14686	KMT2D	P24941	CDK2	S582	E577Q	577	Missense	distal	-5	no	13.351	13.314	EPSD	COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	O14686	KMT2D	P24941	CDK2	S582	P583L	583	Missense	proximal	1	no	13.351	3.530	EPSD	COSMIC	8.148	Loss
CMGC_CDK_CDK2_CDK2_ST	O14686	KMT2D	P24941	CDK2	S588	P589L	589	Missense	proximal	1	no	13.239	3.418	EPSD	COSMIC	8.148	Loss
CMGC_CDK_CDK2_CDK2_ST	O14686	KMT2D	P24941	CDK2	S588	P594L	594	Missense	distal	6	no	13.239	13.241	EPSD	COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	O14686	KMT2D	P24941	CDK2	S588	P583L	583	Missense	distal	-5	no	13.239	13.251	EPSD	COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	O14686	KMT2D	P24941	CDK2	S588	E595K	595	Missense	distal	7	no	13.239	12.909	EPSD	COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	O14686	KMT2D	P24941	CDK2	S591	P589L	589	Missense	proximal	-2	no	14.123	13.898	EPSD	COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	O14686	KMT2D	P24941	CDK2	S591	P594L	594	Missense	distal	3	no	14.123	13.739	EPSD	COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	O14686	KMT2D	P24941	CDK2	S591	E595K	595	Missense	distal	4	no	14.123	14.508	EPSD	COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	O14686	KMT2D	P24941	CDK2	S606	P601L	601	Missense	distal	-5	no	13.374	13.385	EPSD	COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	O14686	KMT2D	P24941	CDK2	S606	S606C	606	Missense	central	0	yes	13.374	0.000	EPSD	COSMIC	8.148	Loss
CMGC_CDK_CDK2_CDK2_ST	O14686	KMT2D	P24941	CDK2	S606	S609F	609	Missense	distal	3	no	13.374	13.299	EPSD	COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	O14686	KMT2D	P24941	CDK2	S609	S606C	606	Missense	distal	-3	no	11.823	11.831	EPSD	COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	O14686	KMT2D	P24941	CDK2	S609	S609F	609	Missense	central	0	yes	11.823	0.000	EPSD	COSMIC	8.148	Loss
CMGC_CDK_CDK2_CDK2_ST	O14686	KMT2D	P24941	CDK2	S615	P620L	620	Missense	distal	5	no	13.518	13.557	EPSD	COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	O14686	KMT2D	P24941	CDK2	S615	P619S	619	Missense	distal	4	no	13.518	13.531	EPSD	COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	O14686	KMT2D	P24941	CDK2	S615	S609F	609	Missense	distal	-6	no	13.518	13.523	EPSD	COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	O14686	KMT2D	P24941	CDK2	S618	P620L	620	Missense	proximal	2	no	13.691	13.584	EPSD	COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	O14686	KMT2D	P24941	CDK2	S618	P619S	619	Missense	proximal	1	no	13.691	2.425	EPSD	COSMIC	8.148	Loss
CMGC_CDK_CDK2_CDK2_ST	O14686	KMT2D	P24941	CDK2	S618	R625C	625	Missense	distal	7	no	13.691	13.842	EPSD	COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	O14686	KMT2D	P24941	CDK2	S618	S624P	624	Missense	distal	6	no	13.691	13.689	EPSD	COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	O14686	KMT2D	P24941	CDK2	S627	P620L	620	Missense	distal	-7	no	12.679	12.685	EPSD	COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	O14686	KMT2D	P24941	CDK2	S627	S627F	627	Missense	central	0	yes	12.679	0.000	EPSD	COSMIC	8.148	Loss
CMGC_CDK_CDK2_CDK2_ST	O14686	KMT2D	P24941	CDK2	S627	R625C	625	Missense	proximal	-2	no	12.679	12.854	EPSD	COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	O14686	KMT2D	P24941	CDK2	S627	S624P	624	Missense	distal	-3	no	12.679	12.584	EPSD	COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	O14686	KMT2D	P24941	CDK2	S627	P630H	630	Missense	distal	3	no	12.679	13.701	EPSD	COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	O14686	KMT2D	P24941	CDK2	S627	E631K	631	Missense	distal	4	no	12.679	13.064	EPSD	COSMIC;GDSC;CCLE	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	O14686	KMT2D	P24941	CDK2	S633	S627F	627	Missense	distal	-6	no	13.703	13.708	EPSD	COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	O14686	KMT2D	P24941	CDK2	S633	P630H	630	Missense	distal	-3	no	13.703	13.849	EPSD	COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	O14686	KMT2D	P24941	CDK2	S633	E631K	631	Missense	proximal	-2	no	13.703	14.304	EPSD	COSMIC;GDSC;CCLE	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	O14686	KMT2D	P24941	CDK2	S633	S633L	633	Missense	central	0	yes	13.703	0.000	EPSD	COSMIC	8.148	Loss
CMGC_CDK_CDK2_CDK2_ST	O14686	KMT2D	P24941	CDK2	S636	P630H	630	Missense	distal	-6	no	13.957	13.960	EPSD	COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	O14686	KMT2D	P24941	CDK2	S636	E631K	631	Missense	distal	-5	no	13.957	13.922	EPSD	COSMIC;GDSC;CCLE	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	O14686	KMT2D	P24941	CDK2	S636	S633L	633	Missense	distal	-3	no	13.957	13.791	EPSD	COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	O14686	KMT2D	P24941	CDK2	S642	M644I	644	Missense	proximal	2	no	13.362	13.128	EPSD	COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	O14686	KMT2D	P24941	CDK2	S642	P647T	647	Missense	distal	5	no	13.362	13.336	EPSD	COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	O14686	KMT2D	P24941	CDK2	S642	P647Q	647	Missense	distal	5	no	13.362	13.322	EPSD	COSMIC;GDSC;CCLE	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	O14686	KMT2D	P24941	CDK2	S642	P647L	647	Missense	distal	5	no	13.362	13.402	EPSD	COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	O14686	KMT2D	P24941	CDK2	S642	M644T	644	Missense	proximal	2	no	13.362	12.973	EPSD	COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	O14686	KMT2D	P24941	CDK2	S645	M644I	644	Missense	proximal	-1	no	13.230	12.163	EPSD	COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	O14686	KMT2D	P24941	CDK2	S645	P647T	647	Missense	proximal	2	no	13.230	13.053	EPSD	COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	O14686	KMT2D	P24941	CDK2	S645	P647Q	647	Missense	proximal	2	no	13.230	13.289	EPSD	COSMIC;GDSC;CCLE	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	O14686	KMT2D	P24941	CDK2	S645	P647L	647	Missense	proximal	2	no	13.230	13.123	EPSD	COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	O14686	KMT2D	P24941	CDK2	S645	M644T	644	Missense	proximal	-1	no	13.230	11.917	EPSD	COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	O14686	KMT2D	P24941	CDK2	S654	P647T	647	Missense	distal	-7	no	11.205	11.202	EPSD	COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	O14686	KMT2D	P24941	CDK2	S654	P647Q	647	Missense	distal	-7	no	11.205	11.162	EPSD	COSMIC;GDSC;CCLE	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	O14686	KMT2D	P24941	CDK2	S654	P647L	647	Missense	distal	-7	no	11.205	11.211	EPSD	COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	O14686	KMT2D	P24941	CDK2	S663	P666S	666	Missense	distal	3	no	11.009	11.043	EPSD	COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	O14686	KMT2D	P24941	CDK2	S663	E668K	668	Missense	distal	5	no	11.009	10.876	EPSD	COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	O14686	KMT2D	P24941	CDK2	S663	P665R	665	Missense	proximal	2	no	11.009	11.168	EPSD	COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	O14686	KMT2D	P24941	CDK2	S663	S660L	660	Missense	distal	-3	no	11.009	10.843	EPSD	COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	O14686	KMT2D	P24941	CDK2	S669	P666S	666	Missense	distal	-3	no	12.383	12.478	EPSD	COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	O14686	KMT2D	P24941	CDK2	S669	E668K	668	Missense	proximal	-1	no	12.383	11.497	EPSD	COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	O14686	KMT2D	P24941	CDK2	S669	P665R	665	Missense	distal	-4	no	12.383	12.140	EPSD	COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	O14686	KMT2D	P24941	CDK2	S669	P674S	674	Missense	distal	5	no	12.383	12.282	EPSD	COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	O14686	KMT2D	P24941	CDK2	S672	P666S	666	Missense	distal	-6	no	12.318	12.317	EPSD	COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	O14686	KMT2D	P24941	CDK2	S672	E668K	668	Missense	distal	-4	no	12.318	12.007	EPSD	COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	O14686	KMT2D	P24941	CDK2	S672	P665R	665	Missense	distal	-7	no	12.318	12.662	EPSD	COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	O14686	KMT2D	P24941	CDK2	S672	P674S	674	Missense	proximal	2	no	12.318	12.385	EPSD	COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	O14686	KMT2D	P24941	CDK2	S678	E685K	685	Missense	distal	7	no	12.374	12.043	EPSD	COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	O14686	KMT2D	P24941	CDK2	S678	T680S	680	Missense	proximal	2	no	12.374	12.618	EPSD	COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	O14686	KMT2D	P24941	CDK2	S678	P674S	674	Missense	distal	-4	no	12.374	12.728	EPSD	COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	O14686	KMT2D	P24941	CDK2	S681	E685K	685	Missense	distal	4	no	12.996	13.381	EPSD	COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	O14686	KMT2D	P24941	CDK2	S681	R688C	688	Missense	distal	7	no	12.996	13.148	EPSD	COSMIC;GDSC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	O14686	KMT2D	P24941	CDK2	S681	T680S	680	Missense	proximal	-1	no	12.996	12.789	EPSD	COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	O14686	KMT2D	P24941	CDK2	S681	P674S	674	Missense	distal	-7	no	12.996	12.816	EPSD	COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	O14686	KMT2D	P24941	CDK2	S744	R737W	737	Missense	distal	-7	no	12.383	12.554	EPSD	COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	O14686	KMT2D	P24941	CDK2	S744	E748K	748	Missense	distal	4	no	12.383	12.768	EPSD	COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	O14686	KMT2D	P24941	CDK2	S744	G740W	740	Missense	distal	-4	no	12.383	11.701	EPSD	COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	O14686	KMT2D	P24941	CDK2	S744	S744L	744	Missense	central	0	yes	12.383	0.000	EPSD	COSMIC	8.148	Loss
CMGC_CDK_CDK2_CDK2_ST	O14686	KMT2D	P24941	CDK2	S753	P754L	754	Missense	proximal	1	no	12.827	3.006	EPSD	COSMIC	8.148	Loss
CMGC_CDK_CDK2_CDK2_ST	O14686	KMT2D	P24941	CDK2	S753	P754S	754	Missense	proximal	1	no	12.827	1.561	EPSD	COSMIC	8.148	Loss
CMGC_CDK_CDK2_CDK2_ST	O14686	KMT2D	P24941	CDK2	S753	S753F	753	Missense	central	0	yes	12.827	0.000	EPSD	COSMIC	8.148	Loss
CMGC_CDK_CDK2_CDK2_ST	O14686	KMT2D	P24941	CDK2	S753	E748K	748	Missense	distal	-5	no	12.827	12.793	EPSD	COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	O14686	KMT2D	P24941	CDK2	S753	R755W	755	Missense	proximal	2	no	12.827	12.924	EPSD	COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	O14686	KMT2D	P24941	CDK2	S762	P768L	768	Missense	distal	6	no	12.215	12.216	EPSD	COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	O14686	KMT2D	P24941	CDK2	S762	A765P	765	Missense	distal	3	no	12.215	12.726	EPSD	COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	O14686	KMT2D	P24941	CDK2	S762	Q764R	764	Missense	proximal	2	no	12.215	12.314	EPSD	COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	O14686	KMT2D	P24941	CDK2	S762	P763S	763	Missense	proximal	1	no	12.215	0.949	EPSD	COSMIC	8.148	Loss
CMGC_CDK_CDK2_CDK2_ST	O14686	KMT2D	P24941	CDK2	S762	R755W	755	Missense	distal	-7	no	12.215	12.385	EPSD	COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	O14686	KMT2D	P24941	CDK2	S762	E767K	767	Missense	distal	5	no	12.215	12.081	EPSD	COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	O14686	KMT2D	P24941	CDK2	S952	L954F	954	Missense	proximal	2	no	13.678	14.035	EPSD	COSMIC;CCLE	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	O14686	KMT2D	P24941	CDK2	S952	Y959C	959	Missense	distal	7	no	13.678	14.049	EPSD	COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	O14686	KMT2D	P24941	CDK2	S1037	Q1041L	1041	Missense	distal	4	no	10.916	10.966	EPSD	COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	O14686	KMT2D	P24941	CDK2	S1037	H1030N	1030	Missense	distal	-7	no	10.916	10.711	EPSD	COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	O14686	KMT2D	P24941	CDK2	S1037	S1031F	1031	Missense	distal	-6	no	10.916	10.921	EPSD	COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	O14686	KMT2D	P24941	CDK2	S1043	Q1041L	1041	Missense	proximal	-2	no	10.603	10.946	EPSD	COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	O14686	KMT2D	P24941	CDK2	S1146	P1152L	1152	Missense	distal	6	no	8.404	8.405	EPSD	COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	O14686	KMT2D	P24941	CDK2	S1146	P1152H	1152	Missense	distal	6	no	8.404	8.399	EPSD	COSMIC;GDSC;CCLE	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	O14686	KMT2D	P24941	CDK2	S1151	P1152L	1152	Missense	proximal	1	no	14.631	4.810	EPSD	COSMIC	8.148	Loss
CMGC_CDK_CDK2_CDK2_ST	O14686	KMT2D	P24941	CDK2	S1151	P1152H	1152	Missense	proximal	1	no	14.631	7.873	EPSD	COSMIC;GDSC;CCLE	8.148	Loss
CMGC_CDK_CDK2_CDK2_ST	O14686	KMT2D	P24941	CDK2	S1151	P1157L	1157	Missense	distal	6	no	14.631	14.633	EPSD	COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	O14686	KMT2D	P24941	CDK2	S1151	E1158K	1158	Missense	distal	7	no	14.631	14.301	EPSD	COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	O14686	KMT2D	P24941	CDK2	T1164	E1159Q	1159	Missense	distal	-5	no	13.764	13.726	EPSD	COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	O14686	KMT2D	P24941	CDK2	T1164	P1170L	1170	Missense	distal	6	no	13.764	13.765	EPSD	COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	O14686	KMT2D	P24941	CDK2	T1164	P1157L	1157	Missense	distal	-7	no	13.764	13.769	EPSD	COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	O14686	KMT2D	P24941	CDK2	T1164	E1158K	1158	Missense	distal	-6	no	13.764	13.761	EPSD	COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	O14686	KMT2D	P24941	CDK2	S1180	A1176T	1176	Missense	distal	-4	no	16.075	16.300	EPSD	COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	O14686	KMT2D	P24941	CDK2	S1180	P1181S	1181	Missense	proximal	1	no	16.075	4.809	EPSD	COSMIC	8.148	Loss
CMGC_CDK_CDK2_CDK2_ST	O14686	KMT2D	P24941	CDK2	S1180	E1187K	1187	Missense	distal	7	no	16.075	15.744	EPSD	COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	O14686	KMT2D	P24941	CDK2	S1180	E1184K	1184	Missense	distal	4	no	16.075	16.459	EPSD	COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	O14686	KMT2D	P24941	CDK2	T1195	P1191L	1191	Missense	distal	-4	no	14.225	14.166	EPSD	COSMIC;GDSC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	O14686	KMT2D	P24941	CDK2	S1249	G1255D	1255	Missense	distal	6	no	16.439	16.435	EPSD	COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	O14686	KMT2D	P24941	CDK2	S1249	S1256F	1256	Missense	distal	7	no	16.439	17.292	EPSD	COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	O14686	KMT2D	P24941	CDK2	S1280	G1281R	1281	Missense	proximal	1	no	8.271	5.784	EPSD	COSMIC	8.148	Loss
CMGC_CDK_CDK2_CDK2_ST	O14686	KMT2D	P24941	CDK2	S1280	D1274N	1274	Missense	distal	-6	no	8.271	8.272	EPSD	COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	O14686	KMT2D	P24941	CDK2	S1294	R1291W	1291	Missense	distal	-3	no	15.567	15.648	EPSD	COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	O14686	KMT2D	P24941	CDK2	S1294	R1291Q	1291	Missense	distal	-3	no	15.567	15.436	EPSD	COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	O14686	KMT2D	P24941	CDK2	S1294	S1294Y	1294	Missense	central	0	yes	15.567	0.000	EPSD	COSMIC	8.148	Loss
CMGC_CDK_CDK2_CDK2_ST	O14686	KMT2D	P24941	CDK2	S1294	K1301N	1301	Missense	distal	7	no	15.567	15.760	EPSD	COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	O14686	KMT2D	P24941	CDK2	S1294	S1294F	1294	Missense	central	0	yes	15.567	0.000	EPSD	COSMIC	8.148	Loss
CMGC_CDK_CDK2_CDK2_ST	O14686	KMT2D	P24941	CDK2	S1298	R1291W	1291	Missense	distal	-7	no	8.882	9.052	EPSD	COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	O14686	KMT2D	P24941	CDK2	S1298	R1291Q	1291	Missense	distal	-7	no	8.882	8.495	EPSD	COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	O14686	KMT2D	P24941	CDK2	S1298	S1294Y	1294	Missense	distal	-4	no	8.882	8.993	EPSD	COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	O14686	KMT2D	P24941	CDK2	S1298	K1301N	1301	Missense	distal	3	no	8.882	5.612	EPSD	COSMIC	8.148	Loss
CMGC_CDK_CDK2_CDK2_ST	O14686	KMT2D	P24941	CDK2	S1298	R1304H	1304	Missense	distal	6	no	8.882	8.893	EPSD	COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	O14686	KMT2D	P24941	CDK2	S1298	S1294F	1294	Missense	distal	-4	no	8.882	7.920	EPSD	COSMIC	8.148	Loss
CMGC_CDK_CDK2_CDK2_ST	O14686	KMT2D	P24941	CDK2	S1298	G1303D	1303	Missense	distal	5	no	8.882	8.929	EPSD	COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	O14686	KMT2D	P24941	CDK2	S1298	S1305N	1305	Missense	distal	7	no	8.882	8.940	EPSD	COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	O14686	KMT2D	P24941	CDK2	S1606	P1607S	1607	Missense	proximal	1	no	16.246	4.980	EPSD	COSMIC	8.148	Loss
CMGC_CDK_CDK2_CDK2_ST	O14686	KMT2D	P24941	CDK2	S1606	R1611Q	1611	Missense	distal	5	no	16.246	16.099	EPSD	COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	O14686	KMT2D	P24941	CDK2	S1606	R1601C	1601	Missense	distal	-5	no	16.246	16.279	EPSD	COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	O14686	KMT2D	P24941	CDK2	S1606	H1609Y	1609	Missense	distal	3	no	16.246	14.478	EPSD	COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	O14686	KMT2D	P24941	CDK2	S1606	N1602D	1602	Missense	distal	-4	no	16.246	16.634	EPSD	COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	O14686	KMT2D	P24941	CDK2	S1671	P1672S	1672	Missense	proximal	1	no	15.472	4.206	EPSD	COSMIC	8.148	Loss
CMGC_CDK_CDK2_CDK2_ST	O14686	KMT2D	P24941	CDK2	S1671	P1669L	1669	Missense	proximal	-2	no	15.472	15.247	EPSD	COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	O14686	KMT2D	P24941	CDK2	S1671	E1667D	1667	Missense	distal	-4	no	15.472	15.768	EPSD	COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	O14686	KMT2D	P24941	CDK2	S1671	G1668D	1668	Missense	distal	-3	no	15.472	15.433	EPSD	COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	O14686	KMT2D	P24941	CDK2	S1671	I1664V	1664	Missense	distal	-7	no	15.472	15.297	EPSD	COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	O14686	KMT2D	P24941	CDK2	S1671	V1670I	1670	Missense	proximal	-1	no	15.472	15.498	EPSD	COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	O14686	KMT2D	P24941	CDK2	S1671	P1672T	1672	Missense	proximal	1	no	15.472	5.514	EPSD	COSMIC	8.148	Loss
CMGC_CDK_CDK2_CDK2_ST	O14686	KMT2D	P24941	CDK2	S1671	P1672L	1672	Missense	proximal	1	no	15.472	5.651	EPSD	COSMIC	8.148	Loss
CMGC_CDK_CDK2_CDK2_ST	O14686	KMT2D	P24941	CDK2	T1803	G1808R	1808	Missense	distal	5	no	14.035	14.014	EPSD	COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	O14686	KMT2D	P24941	CDK2	T1803	R1796W	1796	Missense	distal	-7	no	14.035	14.205	EPSD	COSMIC;GDSC;CCLE	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	O14686	KMT2D	P24941	CDK2	T1803	A1806T	1806	Missense	distal	3	no	14.035	14.433	EPSD	COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	O14686	KMT2D	P24941	CDK2	T1803	R1796Q	1796	Missense	distal	-7	no	14.035	13.648	EPSD	COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	O14686	KMT2D	P24941	CDK2	T1803	P1804L	1804	Missense	proximal	1	no	14.035	4.214	EPSD	COSMIC	8.148	Loss
CMGC_CDK_CDK2_CDK2_ST	O14686	KMT2D	P24941	CDK2	T1803	G1808E	1808	Missense	distal	5	no	14.035	13.987	EPSD	COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	O14686	KMT2D	P24941	CDK2	S1820	G1826D	1826	Missense	distal	6	no	8.337	8.333	EPSD	COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	O14686	KMT2D	P24941	CDK2	S1820	P1827L	1827	Missense	distal	7	no	8.337	8.367	EPSD	COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	O14686	KMT2D	P24941	CDK2	S1820	K1822E	1822	Missense	proximal	2	no	8.337	8.574	EPSD	COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	O14686	KMT2D	P24941	CDK2	S1820	D1824Y	1824	Missense	distal	4	no	8.337	8.601	EPSD	COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	O14686	KMT2D	P24941	CDK2	S1820	G1823V	1823	Missense	distal	3	no	8.337	9.046	EPSD	COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	O14686	KMT2D	P24941	CDK2	S1820	L1817H	1817	Missense	distal	-3	no	8.337	8.554	EPSD	COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	O14686	KMT2D	P24941	CDK2	S1820	P1818S	1818	Missense	proximal	-2	no	8.337	7.685	EPSD	COSMIC	8.148	Loss
CMGC_CDK_CDK2_CDK2_ST	O14686	KMT2D	P24941	CDK2	S1834	R1835H	1835	Missense	proximal	1	no	5.540	8.580	EPSD	COSMIC;CCLE	8.148	Gain
CMGC_CDK_CDK2_CDK2_ST	O14686	KMT2D	P24941	CDK2	T1843	E1847Q	1847	Missense	distal	4	no	16.149	16.193	EPSD	COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	O14686	KMT2D	P24941	CDK2	T1843	D1842N	1842	Missense	proximal	-1	no	16.149	15.319	EPSD	COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	O14686	KMT2D	P24941	CDK2	T1843	A1841V	1841	Missense	proximal	-2	no	16.149	15.483	EPSD	COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	O14686	KMT2D	P24941	CDK2	T1843	G1845R	1845	Missense	proximal	2	no	16.149	16.190	EPSD	COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	O14686	KMT2D	P24941	CDK2	T1843	D1842Y	1842	Missense	proximal	-1	no	16.149	15.832	EPSD	COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	O14686	KMT2D	P24941	CDK2	T1843	E1838K	1838	Missense	distal	-5	no	16.149	16.114	EPSD	COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	O14686	KMT2D	P24941	CDK2	S1854	E1847Q	1847	Missense	distal	-7	no	15.691	15.557	EPSD	COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	O14686	KMT2D	P24941	CDK2	T1865	G1867S	1867	Missense	proximal	2	no	16.932	16.880	EPSD	COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	O14686	KMT2D	P24941	CDK2	T1911	R1918C	1918	Missense	distal	7	no	12.443	12.594	EPSD	COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	O14686	KMT2D	P24941	CDK2	T1911	P1912H	1912	Missense	proximal	1	no	12.443	5.684	EPSD	COSMIC	8.148	Loss
CMGC_CDK_CDK2_CDK2_ST	O14686	KMT2D	P24941	CDK2	T1919	R1918C	1918	Missense	proximal	-1	no	12.736	12.039	EPSD	COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	O14686	KMT2D	P24941	CDK2	T1919	L1926F	1926	Missense	distal	7	no	12.736	13.407	EPSD	COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	O14686	KMT2D	P24941	CDK2	T1919	P1912H	1912	Missense	distal	-7	no	12.736	12.859	EPSD	COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	O14686	KMT2D	P24941	CDK2	S1939	L1935P	1935	Missense	distal	-4	no	13.700	13.758	EPSD	COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	O14686	KMT2D	P24941	CDK2	S1939	N1934S	1934	Missense	distal	-5	no	13.700	13.637	EPSD	COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	O14686	KMT2D	P24941	CDK2	S1939	P1940L	1940	Missense	proximal	1	no	13.700	3.879	EPSD	COSMIC	8.148	Loss
CMGC_CDK_CDK2_CDK2_ST	O14686	KMT2D	P24941	CDK2	S1939	G1946S	1946	Missense	distal	7	no	13.700	12.878	EPSD	COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	O14686	KMT2D	P24941	CDK2	S1950	R1956G	1956	Missense	distal	6	no	11.653	11.658	EPSD	COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	O14686	KMT2D	P24941	CDK2	S1950	S1955P	1955	Missense	distal	5	no	11.653	11.754	EPSD	COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	O14686	KMT2D	P24941	CDK2	S1950	G1946S	1946	Missense	distal	-4	no	11.653	12.325	EPSD	COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	O14686	KMT2D	P24941	CDK2	S1950	S1950F	1950	Missense	central	0	yes	11.653	0.000	EPSD	COSMIC	8.148	Loss
CMGC_CDK_CDK2_CDK2_ST	O14686	KMT2D	P24941	CDK2	S1963	R1956G	1956	Missense	distal	-7	no	14.364	14.345	EPSD	COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	O14686	KMT2D	P24941	CDK2	S1963	D1970N	1970	Missense	distal	7	no	14.364	13.584	EPSD	COSMIC;CCLE	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	O14686	KMT2D	P24941	CDK2	S1963	G1959E	1959	Missense	distal	-4	no	14.364	14.913	EPSD	COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	O14686	KMT2D	P24941	CDK2	S1963	P1966L	1966	Missense	distal	3	no	14.364	13.981	EPSD	COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	O14686	KMT2D	P24941	CDK2	S1971	D1970N	1970	Missense	proximal	-1	no	14.181	13.352	EPSD	COSMIC;CCLE	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	O14686	KMT2D	P24941	CDK2	S1971	P1966L	1966	Missense	distal	-5	no	14.181	14.193	EPSD	COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	O14686	KMT2D	P24941	CDK2	T1986	P1984L	1984	Missense	proximal	-2	no	13.815	13.591	EPSD	COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	O14686	KMT2D	P24941	CDK2	T1986	E1992G	1992	Missense	distal	6	no	13.815	13.807	EPSD	COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	O14686	KMT2D	P24941	CDK2	T1986	T1989A	1989	Missense	distal	3	no	13.815	13.417	EPSD	COSMIC;GDSC;CCLE	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	O14686	KMT2D	P24941	CDK2	S2115	A2112T	2112	Missense	distal	-3	no	13.355	13.374	EPSD	COSMIC;CCLE	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	O14686	KMT2D	P24941	CDK2	S2115	P2108S	2108	Missense	distal	-7	no	13.355	13.175	EPSD	COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	O14686	KMT2D	P24941	CDK2	S2115	G2111W	2111	Missense	distal	-4	no	13.355	12.672	EPSD	COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	O14686	KMT2D	P24941	CDK2	S2128	P2129S	2129	Missense	proximal	1	no	15.799	4.533	EPSD	COSMIC	8.148	Loss
CMGC_CDK_CDK2_CDK2_ST	O14686	KMT2D	P24941	CDK2	S2128	P2129L	2129	Missense	proximal	1	no	15.799	5.978	EPSD	COSMIC	8.148	Loss
CMGC_CDK_CDK2_CDK2_ST	O14686	KMT2D	P24941	CDK2	T2131	P2129S	2129	Missense	proximal	-2	no	13.619	12.968	EPSD	COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	O14686	KMT2D	P24941	CDK2	T2131	P2129L	2129	Missense	proximal	-2	no	13.619	13.395	EPSD	COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	O14686	KMT2D	P24941	CDK2	T2131	T2137I	2137	Missense	distal	6	no	13.619	13.612	EPSD	COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	O14686	KMT2D	P24941	CDK2	T2131	T2137A	2137	Missense	distal	6	no	13.619	13.607	EPSD	COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	O14686	KMT2D	P24941	CDK2	S2155	G2152V	2152	Missense	distal	-3	no	14.883	14.923	EPSD	COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	O14686	KMT2D	P24941	CDK2	S2155	S2149T	2149	Missense	distal	-6	no	14.883	14.884	EPSD	COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	O14686	KMT2D	P24941	CDK2	S2201	P2206L	2206	Missense	distal	5	no	10.968	11.008	EPSD	COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	O14686	KMT2D	P24941	CDK2	S2201	P2200S	2200	Missense	proximal	-1	no	10.968	10.497	EPSD	COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	O14686	KMT2D	P24941	CDK2	S2201	A2205S	2205	Missense	distal	4	no	10.968	10.942	EPSD	COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	O14686	KMT2D	P24941	CDK2	S2201	A2207V	2207	Missense	distal	6	no	10.968	10.971	EPSD	COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	O14686	KMT2D	P24941	CDK2	T2229	T2233S	2233	Missense	distal	4	no	14.167	13.898	EPSD	COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	O14686	KMT2D	P24941	CDK2	T2229	P2234S	2234	Missense	distal	5	no	14.167	14.066	EPSD	COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	O14686	KMT2D	P24941	CDK2	T2229	T2228A	2228	Missense	proximal	-1	no	14.167	14.160	EPSD	COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	O14686	KMT2D	P24941	CDK2	T2233	P2234S	2234	Missense	proximal	1	no	15.488	4.222	EPSD	COSMIC	8.148	Loss
CMGC_CDK_CDK2_CDK2_ST	O14686	KMT2D	P24941	CDK2	T2233	T2228A	2228	Missense	distal	-5	no	15.488	15.514	EPSD	COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	O14686	KMT2D	P24941	CDK2	T2240	T2233S	2233	Missense	distal	-7	no	13.084	12.907	EPSD	COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	O14686	KMT2D	P24941	CDK2	T2240	P2247L	2247	Missense	distal	7	no	13.084	13.115	EPSD	COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	O14686	KMT2D	P24941	CDK2	T2240	P2241L	2241	Missense	proximal	1	no	13.084	3.264	EPSD	COSMIC	8.148	Loss
CMGC_CDK_CDK2_CDK2_ST	O14686	KMT2D	P24941	CDK2	T2240	L2245V	2245	Missense	distal	5	no	13.084	13.012	EPSD	COSMIC;GDSC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	O14686	KMT2D	P24941	CDK2	T2240	P2234S	2234	Missense	distal	-6	no	13.084	13.083	EPSD	COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	O14686	KMT2D	P24941	CDK2	S2260	E2259Q	2259	Missense	proximal	-1	no	14.092	12.999	EPSD	COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	O14686	KMT2D	P24941	CDK2	S2274	G2279E	2279	Missense	distal	5	no	12.104	12.056	EPSD	COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	O14686	KMT2D	P24941	CDK2	S2274	P2271S	2271	Missense	distal	-3	no	12.104	12.199	EPSD	COSMIC;GDSC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	O14686	KMT2D	P24941	CDK2	S2274	A2268T	2268	Missense	distal	-6	no	12.104	12.105	EPSD	COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	O14686	KMT2D	P24941	CDK2	S2274	E2270K	2270	Missense	distal	-4	no	12.104	11.793	EPSD	COSMIC;GDSC;CCLE	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	O14686	KMT2D	P24941	CDK2	S2296	G2300E	2300	Missense	distal	4	no	12.463	12.600	EPSD	COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	O14686	KMT2D	P24941	CDK2	S2296	P2297S	2297	Missense	proximal	1	no	12.463	1.197	EPSD	COSMIC	8.148	Loss
CMGC_CDK_CDK2_CDK2_ST	O14686	KMT2D	P24941	CDK2	S2296	P2297L	2297	Missense	proximal	1	no	12.463	2.642	EPSD	COSMIC	8.148	Loss
CMGC_CDK_CDK2_CDK2_ST	O14686	KMT2D	P24941	CDK2	S2296	S2296F	2296	Missense	central	0	yes	12.463	0.000	EPSD	COSMIC	8.148	Loss
CMGC_CDK_CDK2_CDK2_ST	O14686	KMT2D	P24941	CDK2	S2309	V2307I	2307	Missense	proximal	-2	no	12.848	13.344	EPSD	COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	O14686	KMT2D	P24941	CDK2	S2309	G2305S	2305	Missense	distal	-4	no	12.848	13.521	EPSD	COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	O14686	KMT2D	P24941	CDK2	S2309	G2305D	2305	Missense	distal	-4	no	12.848	13.693	EPSD	COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	O14686	KMT2D	P24941	CDK2	S2309	H2315P	2315	Missense	distal	6	no	12.848	12.853	EPSD	COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	O14686	KMT2D	P24941	CDK2	S2309	G2305C	2305	Missense	distal	-4	no	12.848	12.415	EPSD	COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	O14686	KMT2D	P24941	CDK2	S2309	G2313S	2313	Missense	distal	4	no	12.848	12.981	EPSD	COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	O14686	KMT2D	P24941	CDK2	S2309	H2315Y	2315	Missense	distal	6	no	12.848	12.845	EPSD	COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	O14686	KMT2D	P24941	CDK2	S2309	L2304M	2304	Missense	distal	-5	no	12.848	12.943	EPSD	COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	O14686	KMT2D	P24941	CDK2	S2312	V2307I	2307	Missense	distal	-5	no	10.265	10.273	EPSD	COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	O14686	KMT2D	P24941	CDK2	S2312	G2305S	2305	Missense	distal	-7	no	10.265	9.761	EPSD	COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	O14686	KMT2D	P24941	CDK2	S2312	G2305D	2305	Missense	distal	-7	no	10.265	10.182	EPSD	COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	O14686	KMT2D	P24941	CDK2	S2312	H2315P	2315	Missense	distal	3	no	10.265	9.243	EPSD	COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	O14686	KMT2D	P24941	CDK2	S2312	G2305C	2305	Missense	distal	-7	no	10.265	10.211	EPSD	COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	O14686	KMT2D	P24941	CDK2	S2312	S2309T	2309	Missense	distal	-3	no	10.265	10.130	EPSD	COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	O14686	KMT2D	P24941	CDK2	S2312	G2313S	2313	Missense	proximal	1	no	10.265	6.311	EPSD	COSMIC	8.148	Loss
CMGC_CDK_CDK2_CDK2_ST	O14686	KMT2D	P24941	CDK2	S2312	G2317R	2317	Missense	distal	5	no	10.265	10.245	EPSD	COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	O14686	KMT2D	P24941	CDK2	S2312	H2315Y	2315	Missense	distal	3	no	10.265	8.497	EPSD	COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	O14686	KMT2D	P24941	CDK2	T2314	H2315P	2315	Missense	proximal	1	no	7.657	14.416	EPSD	COSMIC	8.148	Gain
CMGC_CDK_CDK2_CDK2_ST	O14686	KMT2D	P24941	CDK2	T2314	G2317R	2317	Missense	distal	3	no	7.657	9.476	EPSD	COSMIC	8.148	Gain
CMGC_CDK_CDK2_CDK2_ST	O14686	KMT2D	P24941	CDK2	T2332	P2333S	2333	Missense	proximal	1	no	11.648	0.382	EPSD	COSMIC	8.148	Loss
CMGC_CDK_CDK2_CDK2_ST	O14686	KMT2D	P24941	CDK2	T2332	V2338I	2338	Missense	distal	6	no	11.648	11.649	EPSD	COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	O14686	KMT2D	P24941	CDK2	T2332	T2332I	2332	Missense	central	0	yes	11.648	0.000	EPSD	COSMIC	8.148	Loss
CMGC_CDK_CDK2_CDK2_ST	O14686	KMT2D	P24941	CDK2	S2342	V2338I	2338	Missense	distal	-4	no	14.397	14.294	EPSD	COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	O14686	KMT2D	P24941	CDK2	S2342	Q2341R	2341	Missense	proximal	-1	no	14.397	15.275	EPSD	COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	O14686	KMT2D	P24941	CDK2	S2342	G2346S	2346	Missense	distal	4	no	14.397	14.530	EPSD	COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	O14686	KMT2D	P24941	CDK2	S2342	P2349L	2349	Missense	distal	7	no	14.397	14.427	EPSD	COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	O14686	KMT2D	P24941	CDK2	S2361	P2354S	2354	Missense	distal	-7	no	15.371	15.191	EPSD	COSMIC;CCLE	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	O14686	KMT2D	P24941	CDK2	S2361	S2364R	2364	Missense	distal	3	no	15.371	17.055	EPSD	COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	O14686	KMT2D	P24941	CDK2	S2361	P2362S	2362	Missense	proximal	1	no	15.371	4.105	EPSD	COSMIC	8.148	Loss
CMGC_CDK_CDK2_CDK2_ST	O14686	KMT2D	P24941	CDK2	S2361	S2364T	2364	Missense	distal	3	no	15.371	15.223	EPSD	COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	O14686	KMT2D	P24941	CDK2	S2414	A2413V	2413	Missense	proximal	-1	no	12.864	13.091	EPSD	COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	O14686	KMT2D	P24941	CDK2	S2414	S2414N	2414	Missense	central	0	yes	12.864	0.000	EPSD	COSMIC	8.148	Loss
CMGC_CDK_CDK2_CDK2_ST	O14686	KMT2D	P24941	CDK2	S2438	T2441S	2441	Missense	distal	3	no	10.891	11.039	EPSD	COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	O14686	KMT2D	P24941	CDK2	S2438	P2437S	2437	Missense	proximal	-1	no	10.891	10.420	EPSD	COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	O14686	KMT2D	P24941	CDK2	S2446	T2441S	2441	Missense	distal	-5	no	11.826	11.782	EPSD	COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	O14686	KMT2D	P24941	CDK2	S2455	Q2458K	2458	Missense	distal	3	no	5.443	8.176	EPSD	COSMIC	8.148	Gain
CMGC_CDK_CDK2_CDK2_ST	O14686	KMT2D	P24941	CDK2	S2455	R2456H	2456	Missense	proximal	1	no	5.443	8.483	EPSD	COSMIC	8.148	Gain
CMGC_CDK_CDK2_CDK2_ST	O14686	KMT2D	P24941	CDK2	S2483	L2484P	2484	Missense	proximal	1	no	6.511	16.332	EPSD	COSMIC	8.148	Gain
CMGC_CDK_CDK2_CDK2_ST	O14686	KMT2D	P24941	CDK2	S2592	G2599R	2599	Missense	distal	7	no	13.596	13.415	EPSD	COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	O14686	KMT2D	P24941	CDK2	S2592	G2591S	2591	Missense	proximal	-1	no	13.596	12.076	EPSD	COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	O14686	KMT2D	P24941	CDK2	S2608	P2612L	2612	Missense	distal	4	no	14.981	15.093	EPSD	COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	O14686	KMT2D	P24941	CDK2	S2608	L2610P	2610	Missense	proximal	2	no	14.981	15.088	EPSD	COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	O14686	KMT2D	P24941	CDK2	S2608	P2609L	2609	Missense	proximal	1	no	14.981	5.160	EPSD	COSMIC	8.148	Loss
CMGC_CDK_CDK2_CDK2_ST	O14686	KMT2D	P24941	CDK2	S2636	R2635Q	2635	Missense	proximal	-1	no	9.649	8.771	EPSD	COSMIC;GDSC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	O14686	KMT2D	P24941	CDK2	S2636	S2629F	2629	Missense	distal	-7	no	9.649	10.200	EPSD	COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	O14686	KMT2D	P24941	CDK2	S2636	S2636L	2636	Missense	central	0	yes	9.649	0.000	EPSD	COSMIC	8.148	Loss
CMGC_CDK_CDK2_CDK2_ST	O14686	KMT2D	P24941	CDK2	S2636	S2640F	2640	Missense	distal	4	no	9.649	9.453	EPSD	COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	O14686	KMT2D	P24941	CDK2	S2636	H2630Y	2630	Missense	distal	-6	no	9.649	9.645	EPSD	COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	O14686	KMT2D	P24941	CDK2	S2640	R2635Q	2635	Missense	distal	-5	no	16.077	16.030	EPSD	COSMIC;GDSC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	O14686	KMT2D	P24941	CDK2	S2640	S2636L	2636	Missense	distal	-4	no	16.077	15.664	EPSD	COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	O14686	KMT2D	P24941	CDK2	S2640	S2640F	2640	Missense	central	0	yes	16.077	0.000	EPSD	COSMIC	8.148	Loss
CMGC_CDK_CDK2_CDK2_ST	O14686	KMT2D	P24941	CDK2	T2664	A2657V	2657	Missense	distal	-7	no	8.390	8.245	EPSD	COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	O14686	KMT2D	P24941	CDK2	T2664	G2671S	2671	Missense	distal	7	no	8.390	7.568	EPSD	COSMIC;GDSC	8.148	Loss
CMGC_CDK_CDK2_CDK2_ST	O14686	KMT2D	P24941	CDK2	T2664	L2661Q	2661	Missense	distal	-3	no	8.390	8.519	EPSD	COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	O14686	KMT2D	P24941	CDK2	T2664	P2662S	2662	Missense	proximal	-2	no	8.390	7.739	EPSD	COSMIC	8.148	Loss
CMGC_CDK_CDK2_CDK2_ST	O14686	KMT2D	P24941	CDK2	S2726	P2727S	2727	Missense	proximal	1	no	13.529	2.264	EPSD	COSMIC	8.148	Loss
CMGC_CDK_CDK2_CDK2_ST	O14686	KMT2D	P24941	CDK2	S2726	G2721V	2721	Missense	distal	-5	no	13.529	13.481	EPSD	COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	O14686	KMT2D	P24941	CDK2	T2737	P2738L	2738	Missense	proximal	1	no	13.241	3.420	EPSD	COSMIC	8.148	Loss
CMGC_CDK_CDK2_CDK2_ST	O14686	KMT2D	P24941	CDK2	T2737	P2738S	2738	Missense	proximal	1	no	13.241	1.975	EPSD	COSMIC	8.148	Loss
CMGC_CDK_CDK2_CDK2_ST	O14686	KMT2D	P24941	CDK2	T2737	G2741W	2741	Missense	distal	4	no	13.241	12.881	EPSD	COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	O14686	KMT2D	P24941	CDK2	T2737	T2737I	2737	Missense	central	0	yes	13.241	0.000	EPSD	COSMIC	8.148	Loss
CMGC_CDK_CDK2_CDK2_ST	O14686	KMT2D	P24941	CDK2	T2737	G2735S	2735	Missense	proximal	-2	no	13.241	13.332	EPSD	COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	O14686	KMT2D	P24941	CDK2	T2742	P2738L	2738	Missense	distal	-4	no	9.069	9.010	EPSD	COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	O14686	KMT2D	P24941	CDK2	T2742	P2738S	2738	Missense	distal	-4	no	9.069	9.423	EPSD	COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	O14686	KMT2D	P24941	CDK2	T2742	G2741W	2741	Missense	proximal	-1	no	9.069	9.145	EPSD	COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	O14686	KMT2D	P24941	CDK2	T2742	T2737I	2737	Missense	distal	-5	no	9.069	9.109	EPSD	COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	O14686	KMT2D	P24941	CDK2	T2742	G2735S	2735	Missense	distal	-7	no	9.069	8.564	EPSD	COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	O14686	KMT2D	P24941	CDK2	T2742	S2747N	2747	Missense	distal	5	no	9.069	9.272	EPSD	COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	O14686	KMT2D	P24941	CDK2	T2742	S2747G	2747	Missense	distal	5	no	9.069	9.296	EPSD	COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	O14686	KMT2D	P24941	CDK2	T2780	P2781S	2781	Missense	proximal	1	no	10.771	-0.495	EPSD	COSMIC	8.148	Loss
CMGC_CDK_CDK2_CDK2_ST	O14686	KMT2D	P24941	CDK2	T2780	R2774Q	2774	Missense	distal	-6	no	10.771	10.772	EPSD	COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	O14686	KMT2D	P24941	CDK2	T2780	P2781T	2781	Missense	proximal	1	no	10.771	0.814	EPSD	COSMIC	8.148	Loss
CMGC_CDK_CDK2_CDK2_ST	O14686	KMT2D	P24941	CDK2	T2780	P2775T	2775	Missense	distal	-5	no	10.771	10.770	EPSD	COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	O14686	KMT2D	P24941	CDK2	S2852	S2852F	2852	Missense	central	0	yes	15.356	0.000	EPSD	COSMIC	8.148	Loss
CMGC_CDK_CDK2_CDK2_ST	O14686	KMT2D	P24941	CDK2	S2852	P2853L	2853	Missense	proximal	1	no	15.356	5.535	EPSD	COSMIC	8.148	Loss
CMGC_CDK_CDK2_CDK2_ST	O14686	KMT2D	P24941	CDK2	T2949	P2950S	2950	Missense	proximal	1	no	12.037	0.771	EPSD	COSMIC	8.148	Loss
CMGC_CDK_CDK2_CDK2_ST	O14686	KMT2D	P24941	CDK2	T2949	T2952P	2952	Missense	distal	3	no	12.037	12.151	EPSD	COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	O14686	KMT2D	P24941	CDK2	T2949	G2954A	2954	Missense	distal	5	no	12.037	11.920	EPSD	COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	O14686	KMT2D	P24941	CDK2	T2949	K2953N	2953	Missense	distal	4	no	12.037	11.615	EPSD	COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	O14686	KMT2D	P24941	CDK2	T2959	N2965S	2965	Missense	distal	6	no	8.464	8.462	EPSD	COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	O14686	KMT2D	P24941	CDK2	T2959	T2952P	2952	Missense	distal	-7	no	8.464	8.467	EPSD	COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	O14686	KMT2D	P24941	CDK2	T2959	G2954A	2954	Missense	distal	-5	no	8.464	8.410	EPSD	COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	O14686	KMT2D	P24941	CDK2	T2959	V2964I	2964	Missense	distal	5	no	8.464	8.590	EPSD	COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	O14686	KMT2D	P24941	CDK2	S3130	S3130F	3130	Missense	central	0	yes	15.075	0.000	EPSD	COSMIC;GDSC;CCLE	8.148	Loss
CMGC_CDK_CDK2_CDK2_ST	O14686	KMT2D	P24941	CDK2	S3130	R3127H	3127	Missense	distal	-3	no	15.075	15.033	EPSD	COSMIC;CCLE	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	O14686	KMT2D	P24941	CDK2	S3130	R3127C	3127	Missense	distal	-3	no	15.075	14.990	EPSD	COSMIC;GDSC;CCLE	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	O14686	KMT2D	P24941	CDK2	S3130	A3137T	3137	Missense	distal	7	no	15.075	14.387	EPSD	COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	O14686	KMT2D	P24941	CDK2	S3130	P3129S	3129	Missense	proximal	-1	no	15.075	14.604	EPSD	COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	O14686	KMT2D	P24941	CDK2	S3130	C3132R	3132	Missense	proximal	2	no	15.075	15.088	EPSD	COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	O14686	KMT2D	P24941	CDK2	T3138	P3145L	3145	Missense	distal	7	no	12.165	12.195	EPSD	COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	O14686	KMT2D	P24941	CDK2	T3138	A3137T	3137	Missense	proximal	-1	no	12.165	12.172	EPSD	COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	O14686	KMT2D	P24941	CDK2	T3138	C3132R	3132	Missense	distal	-6	no	12.165	12.162	EPSD	COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	O14686	KMT2D	P24941	CDK2	T3197	P3192L	3192	Missense	distal	-5	no	16.499	16.511	EPSD	COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	O14686	KMT2D	P24941	CDK2	T3197	T3197I	3197	Missense	central	0	yes	16.499	0.000	EPSD	COSMIC	8.148	Loss
CMGC_CDK_CDK2_CDK2_ST	O14686	KMT2D	P24941	CDK2	T3197	L3195M	3195	Missense	proximal	-2	no	16.499	14.639	EPSD	COSMIC;GDSC;CCLE	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	O14686	KMT2D	P24941	CDK2	S3199	P3192L	3192	Missense	distal	-7	no	14.490	14.496	EPSD	COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	O14686	KMT2D	P24941	CDK2	S3199	T3197I	3197	Missense	proximal	-2	no	14.490	14.370	EPSD	COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	O14686	KMT2D	P24941	CDK2	S3199	L3195M	3195	Missense	distal	-4	no	14.490	13.800	EPSD	COSMIC;GDSC;CCLE	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	O14686	KMT2D	P24941	CDK2	S3478	V3474M	3474	Missense	distal	-4	no	8.737	8.036	EPSD	COSMIC	8.148	Loss
CMGC_CDK_CDK2_CDK2_ST	O14686	KMT2D	P24941	CDK2	S3620	A3615T	3615	Missense	distal	-5	no	13.898	13.872	EPSD	COSMIC;CCLE	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	O14686	KMT2D	P24941	CDK2	S3837	Q3839R	3839	Missense	proximal	2	no	13.020	13.120	EPSD	COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	O14686	KMT2D	P24941	CDK2	S3837	S3832F	3832	Missense	distal	-5	no	13.020	13.137	EPSD	COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	O14686	KMT2D	P24941	CDK2	S3986	T3983I	3983	Missense	distal	-3	no	12.479	12.538	EPSD	COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	O14686	KMT2D	P24941	CDK2	S4011	S4010P	4010	Missense	proximal	-1	no	10.269	10.740	EPSD	COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	O14686	KMT2D	P24941	CDK2	S4011	P4012L	4012	Missense	proximal	1	no	10.269	0.448	EPSD	COSMIC	8.148	Loss
CMGC_CDK_CDK2_CDK2_ST	O14686	KMT2D	P24941	CDK2	S4011	A4014V	4014	Missense	distal	3	no	10.269	11.389	EPSD	COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	O14686	KMT2D	P24941	CDK2	S4011	P4017S	4017	Missense	distal	6	no	10.269	10.270	EPSD	COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	O14686	KMT2D	P24941	CDK2	S4215	L4222V	4222	Missense	distal	7	no	12.661	12.889	EPSD	COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	O14686	KMT2D	P24941	CDK2	S4215	R4212W	4212	Missense	distal	-3	no	12.661	12.742	EPSD	COSMIC;GDSC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	O14686	KMT2D	P24941	CDK2	S4215	R4212Q	4212	Missense	distal	-3	no	12.661	12.530	EPSD	COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	O14686	KMT2D	P24941	CDK2	T4308	P4304L	4304	Missense	distal	-4	no	11.652	11.593	EPSD	COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	O14686	KMT2D	P24941	CDK2	T4308	V4305F	4305	Missense	distal	-3	no	11.652	11.696	EPSD	COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	O14686	KMT2D	P24941	CDK2	T4308	P4309L	4309	Missense	proximal	1	no	11.652	1.831	EPSD	COSMIC	8.148	Loss
CMGC_CDK_CDK2_CDK2_ST	O14686	KMT2D	P24941	CDK2	T4308	G4303S	4303	Missense	distal	-5	no	11.652	11.528	EPSD	COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	O14686	KMT2D	P24941	CDK2	T4308	P4304H	4304	Missense	distal	-4	no	11.652	11.048	EPSD	COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	O14686	KMT2D	P24941	CDK2	T4308	P4307S	4307	Missense	proximal	-1	no	11.652	11.181	EPSD	COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	O14686	KMT2D	P24941	CDK2	S4313	P4309L	4309	Missense	distal	-4	no	14.715	14.657	EPSD	COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	O14686	KMT2D	P24941	CDK2	S4313	P4307S	4307	Missense	distal	-6	no	14.715	14.714	EPSD	COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	O14686	KMT2D	P24941	CDK2	S4313	K4318N	4318	Missense	distal	5	no	14.715	14.872	EPSD	COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	O14686	KMT2D	P24941	CDK2	S4313	P4320A	4320	Missense	distal	7	no	14.715	15.100	EPSD	COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	O14686	KMT2D	P24941	CDK2	S4325	S4328T	4328	Missense	distal	3	no	14.343	14.195	EPSD	COSMIC;GDSC;CCLE	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	O14686	KMT2D	P24941	CDK2	S4325	L4323S	4323	Missense	proximal	-2	no	14.343	13.917	EPSD	COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	O14686	KMT2D	P24941	CDK2	S4325	K4318N	4318	Missense	distal	-7	no	14.343	14.309	EPSD	COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	O14686	KMT2D	P24941	CDK2	S4325	P4326S	4326	Missense	proximal	1	no	14.343	3.078	EPSD	COSMIC	8.148	Loss
CMGC_CDK_CDK2_CDK2_ST	O14686	KMT2D	P24941	CDK2	S4325	T4332A	4332	Missense	distal	7	no	14.343	15.032	EPSD	COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	O14686	KMT2D	P24941	CDK2	S4325	P4331L	4331	Missense	distal	6	no	14.343	14.345	EPSD	COSMIC;GDSC;CCLE	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	O14686	KMT2D	P24941	CDK2	S4325	P4320A	4320	Missense	distal	-5	no	14.343	14.368	EPSD	COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	O14686	KMT2D	P24941	CDK2	T4343	P4349A	4349	Missense	distal	6	no	13.746	13.742	EPSD	COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	O14686	KMT2D	P24941	CDK2	T4343	P4349L	4349	Missense	distal	6	no	13.746	13.747	EPSD	COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	O14686	KMT2D	P24941	CDK2	T4343	K4345T	4345	Missense	proximal	2	no	13.746	13.709	EPSD	COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	O14686	KMT2D	P24941	CDK2	T4343	P4338A	4338	Missense	distal	-5	no	13.746	13.771	EPSD	COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	O14686	KMT2D	P24941	CDK2	T4343	G4348R	4348	Missense	distal	5	no	13.746	13.726	EPSD	COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	O14686	KMT2D	P24941	CDK2	T4343	T4343I	4343	Missense	central	0	yes	13.746	0.000	EPSD	COSMIC	8.148	Loss
CMGC_CDK_CDK2_CDK2_ST	O14686	KMT2D	P24941	CDK2	S4359	P4355S	4355	Missense	distal	-4	no	11.461	11.815	EPSD	COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	O14686	KMT2D	P24941	CDK2	S4359	V4358I	4358	Missense	proximal	-1	no	11.461	11.487	EPSD	COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	O14686	KMT2D	P24941	CDK2	S4359	R4357G	4357	Missense	proximal	-2	no	11.461	11.954	EPSD	COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	O14686	KMT2D	P24941	CDK2	S4359	P4355L	4355	Missense	distal	-4	no	11.461	11.402	EPSD	COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	O14686	KMT2D	P24941	CDK2	T4505	Q4500E	4500	Missense	distal	-5	no	14.516	14.553	EPSD	COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	O14686	KMT2D	P24941	CDK2	T4505	P4506L	4506	Missense	proximal	1	no	14.516	4.695	EPSD	COSMIC	8.148	Loss
CMGC_CDK_CDK2_CDK2_ST	O14686	KMT2D	P24941	CDK2	T4519	V4525L	4525	Missense	distal	6	no	13.314	13.317	EPSD	COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	O14686	KMT2D	P24941	CDK2	T4519	R4524Q	4524	Missense	distal	5	no	13.314	13.168	EPSD	COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	O14686	KMT2D	P24941	CDK2	T4519	P4520L	4520	Missense	proximal	1	no	13.314	3.494	EPSD	COSMIC	8.148	Loss
CMGC_CDK_CDK2_CDK2_ST	O14686	KMT2D	P24941	CDK2	T4519	K4523R	4523	Missense	distal	4	no	13.314	12.793	EPSD	COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	O14686	KMT2D	P24941	CDK2	T4519	P4522S	4522	Missense	distal	3	no	13.314	13.349	EPSD	COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	O14686	KMT2D	P24941	CDK2	S4534	S4535P	4535	Missense	proximal	1	no	5.493	16.759	EPSD	COSMIC	8.148	Gain
CMGC_CDK_CDK2_CDK2_ST	O14686	KMT2D	P24941	CDK2	T4621	S4625L	4625	Missense	distal	4	no	14.941	15.040	EPSD	COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	O14686	KMT2D	P24941	CDK2	T4621	P4620L	4620	Missense	proximal	-1	no	14.941	14.762	EPSD	COSMIC;GDSC;CCLE	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	O14686	KMT2D	P24941	CDK2	T4621	S4624L	4624	Missense	distal	3	no	14.941	14.524	EPSD	COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	O14686	KMT2D	P24941	CDK2	T4621	L4616P	4616	Missense	distal	-5	no	14.941	14.930	EPSD	COSMIC;CCLE	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	O14686	KMT2D	P24941	CDK2	T4621	P4622S	4622	Missense	proximal	1	no	14.941	3.676	EPSD	COSMIC	8.148	Loss
CMGC_CDK_CDK2_CDK2_ST	O14686	KMT2D	P24941	CDK2	T4621	P4628S	4628	Missense	distal	7	no	14.941	14.789	EPSD	COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	O14686	KMT2D	P24941	CDK2	T4621	P4623L	4623	Missense	proximal	2	no	14.941	14.835	EPSD	COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	O14686	KMT2D	P24941	CDK2	T4629	S4625L	4625	Missense	distal	-4	no	12.910	12.498	EPSD	COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	O14686	KMT2D	P24941	CDK2	T4629	S4624L	4624	Missense	distal	-5	no	12.910	12.966	EPSD	COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	O14686	KMT2D	P24941	CDK2	T4629	P4631L	4631	Missense	proximal	2	no	12.910	12.804	EPSD	COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	O14686	KMT2D	P24941	CDK2	T4629	P4622S	4622	Missense	distal	-7	no	12.910	12.730	EPSD	COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	O14686	KMT2D	P24941	CDK2	T4629	P4631T	4631	Missense	proximal	2	no	12.910	12.733	EPSD	COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	O14686	KMT2D	P24941	CDK2	T4629	P4632L	4632	Missense	distal	3	no	12.910	12.527	EPSD	COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	O14686	KMT2D	P24941	CDK2	T4629	P4628S	4628	Missense	proximal	-1	no	12.910	12.439	EPSD	COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	O14686	KMT2D	P24941	CDK2	T4643	V4642I	4642	Missense	proximal	-1	no	13.882	13.908	EPSD	COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	O14686	KMT2D	P24941	CDK2	T4682	A4679S	4679	Missense	distal	-3	no	15.577	15.731	EPSD	COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	O14686	KMT2D	P24941	CDK2	S4710	G4716R	4716	Missense	distal	6	no	13.178	13.173	EPSD	COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	O14686	KMT2D	P24941	CDK2	S4710	E4712K	4712	Missense	proximal	2	no	13.178	12.940	EPSD	COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	O14686	KMT2D	P24941	CDK2	S4710	A4708T	4708	Missense	proximal	-2	no	13.178	13.128	EPSD	COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	O14686	KMT2D	P24941	CDK2	S4710	I4705V	4705	Missense	distal	-5	no	13.178	13.169	EPSD	COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	O14686	KMT2D	P24941	CDK2	S4738	R4735W	4735	Missense	distal	-3	no	14.964	15.045	EPSD	COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	O14686	KMT2D	P24941	CDK2	S4738	P4745H	4745	Missense	distal	7	no	14.964	15.095	EPSD	COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	O14686	KMT2D	P24941	CDK2	S4738	R4735Q	4735	Missense	distal	-3	no	14.964	14.833	EPSD	COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	O14686	KMT2D	P24941	CDK2	S4738	P4739L	4739	Missense	proximal	1	no	14.964	5.143	EPSD	COSMIC	8.148	Loss
CMGC_CDK_CDK2_CDK2_ST	O14686	KMT2D	P24941	CDK2	S4738	A4736V	4736	Missense	proximal	-2	no	14.964	14.298	EPSD	COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	O14686	KMT2D	P24941	CDK2	S4822	R4825Q	4825	Missense	distal	3	no	15.361	13.617	EPSD	COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	O14686	KMT2D	P24941	CDK2	S4822	P4823T	4823	Missense	proximal	1	no	15.361	5.403	EPSD	COSMIC	8.148	Loss
CMGC_CDK_CDK2_CDK2_ST	O14686	KMT2D	P24941	CDK2	S4822	E4829G	4829	Missense	distal	7	no	15.361	15.986	EPSD	COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	O14686	KMT2D	P24941	CDK2	S4822	R4825W	4825	Missense	distal	3	no	15.361	12.721	EPSD	COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	O14686	KMT2D	P24941	CDK2	S4822	A4826E	4826	Missense	distal	4	no	15.361	15.337	EPSD	COSMIC;GDSC;CCLE	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	O14686	KMT2D	P24941	CDK2	T4828	E4829G	4829	Missense	proximal	1	no	7.701	9.554	EPSD	COSMIC	8.148	Gain
CMGC_CDK_CDK2_CDK2_ST	O14686	KMT2D	P24941	CDK2	S4849	E4842G	4842	Missense	distal	-7	no	13.011	13.245	EPSD	COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	O14686	KMT2D	P24941	CDK2	S4849	S4849R	4849	Missense	central	0	yes	13.011	0.000	EPSD	COSMIC	8.148	Loss
CMGC_CDK_CDK2_CDK2_ST	O14686	KMT2D	P24941	CDK2	S4883	P4884L	4884	Missense	proximal	1	no	15.576	5.755	EPSD	COSMIC;GDSC;CCLE	8.148	Loss
CMGC_CDK_CDK2_CDK2_ST	O14686	KMT2D	P24941	CDK2	S4955	L4950V	4950	Missense	distal	-5	no	13.119	13.139	EPSD	COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	O14686	KMT2D	P24941	CDK2	S4955	S4955Y	4955	Missense	central	0	yes	13.119	0.000	EPSD	COSMIC	8.148	Loss
CMGC_CDK_CDK2_CDK2_ST	O14686	KMT2D	P24941	CDK2	S4955	R4960Q	4960	Missense	distal	5	no	13.119	12.973	EPSD	COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	O14686	KMT2D	P24941	CDK2	T5347	R5340Q	5340	Missense	distal	-7	no	11.255	10.869	EPSD	COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	O14686	KMT2D	P24941	CDK2	T5347	R5340L	5340	Missense	distal	-7	no	11.255	10.917	EPSD	COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	O14686	KMT2D	P24941	CDK2	T5374	E5371K	5371	Missense	distal	-3	no	15.651	15.435	PhosphoSitePlus	COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	P29590	PML	P24941	CDK2	T28	P26S	26	Missense	proximal	-2	no	14.994	14.343	EPSD	COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	P29590	PML	P24941	CDK2	S38	R44Q	44	Missense	distal	6	no	14.577	14.599	EPSD	COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	P29590	PML	P24941	CDK2	S40	R44Q	44	Missense	distal	4	no	13.816	13.998	EPSD	COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	P29590	PML	P24941	CDK2	T196	T198M	198	Missense	proximal	2	no	14.219	14.608	EPSD	COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	P29590	PML	P24941	CDK2	T196	N193S	193	Missense	distal	-3	no	14.219	14.294	EPSD	COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	P29590	PML	P24941	CDK2	S221	K226M	226	Missense	distal	5	no	8.287	8.649	EPSD	COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	P29590	PML	P24941	CDK2	S221	D228N	228	Missense	distal	7	no	8.287	7.507	EPSD	COSMIC	8.148	Loss
CMGC_CDK_CDK2_CDK2_ST	P29590	PML	P24941	CDK2	T391	C389Y	389	Missense	proximal	-2	no	9.259	9.756	EPSD	COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	P29590	PML	P24941	CDK2	T391	Q392K	392	Missense	proximal	1	no	9.259	-0.480	EPSD	COSMIC	8.148	Loss
CMGC_CDK_CDK2_CDK2_ST	P29590	PML	P24941	CDK2	T482	Q483P	483	Missense	proximal	1	no	6.946	14.857	EPSD	COSMIC	8.148	Gain
CMGC_CDK_CDK2_CDK2_ST	P29590	PML	P24941	CDK2	S505	P506L	506	Missense	proximal	1	no	11.013	1.192	EPSD	COSMIC	8.148	Loss
CMGC_CDK_CDK2_CDK2_ST	P29590	PML	P24941	CDK2	T513	S514P	514	Missense	proximal	1	no	0.300	11.566	EPSD	COSMIC	8.148	Gain
CMGC_CDK_CDK2_CDK2_ST	P29590	PML	P24941	CDK2	S518	S514P	514	Missense	distal	-4	no	16.502	16.147	PhosphoSitePlus	COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	P29590	PML	P24941	CDK2	S561	S562P	562	Missense	proximal	1	no	-0.190	11.076	EPSD	COSMIC	8.148	Gain
CMGC_CDK_CDK2_CDK2_ST	P29590	PML	P24941	CDK2	T867	G871D	871	Missense	distal	4	no	12.361	12.416	EPSD	COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	P29590	PML	P24941	CDK2	T867	R872H	872	Missense	distal	5	no	12.361	12.333	EPSD	COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	Q13242	SRSF9	P24941	CDK2	S197	R194W	194	Missense	distal	-3	no	9.099	9.180	EPSD	COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	Q13242	SRSF9	P24941	CDK2	S216	P220S	220	Missense	distal	4	no	17.779	17.792	PhosphoSitePlus	COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	Q05682	CALD1	P24941	CDK2	T86	T82I	82	Missense	distal	-4	no	9.164	8.846	EPSD	COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	Q05682	CALD1	P24941	CDK2	T86	D91N	91	Missense	distal	5	no	9.164	9.093	EPSD	COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	Q05682	CALD1	P24941	CDK2	S129	L130P	130	Missense	proximal	1	no	4.725	14.546	EPSD	COSMIC	8.148	Gain
CMGC_CDK_CDK2_CDK2_ST	Q05682	CALD1	P24941	CDK2	S248	E242K	242	Missense	distal	-6	no	8.295	8.292	EPSD	COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	Q05682	CALD1	P24941	CDK2	S252	K256N	256	Missense	distal	4	no	8.892	8.471	EPSD	COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	Q05682	CALD1	P24941	CDK2	S511	R512H	512	Missense	proximal	1	no	6.329	9.369	EPSD	COSMIC	8.148	Gain
CMGC_CDK_CDK2_CDK2_ST	Q05682	CALD1	P24941	CDK2	T638	G641S	641	Missense	distal	3	no	9.956	10.091	EPSD	COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	Q05682	CALD1	P24941	CDK2	T638	P633S	633	Missense	distal	-5	no	9.956	9.912	EPSD	COSMIC;GDSC;CCLE	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	Q05682	CALD1	P24941	CDK2	S661	S661I	661	Missense	central	0	yes	8.169	0.000	EPSD	COSMIC	8.148	Loss
CMGC_CDK_CDK2_CDK2_ST	Q05682	CALD1	P24941	CDK2	S661	V657M	657	Missense	distal	-4	no	8.169	7.469	EPSD	COSMIC	8.148	Loss
CMGC_CDK_CDK2_CDK2_ST	Q05682	CALD1	P24941	CDK2	S724	T726I	726	Missense	proximal	2	no	12.072	12.227	EPSD	COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	Q05682	CALD1	P24941	CDK2	T730	T726I	726	Missense	distal	-4	no	17.797	17.479	PhosphoSitePlus	COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	Q05682	CALD1	P24941	CDK2	T730	N732H	732	Missense	proximal	2	no	17.797	17.945	PhosphoSitePlus	COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	Q05682	CALD1	P24941	CDK2	T730	K733N	733	Missense	distal	3	no	17.797	14.527	PhosphoSitePlus	COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	Q05682	CALD1	P24941	CDK2	T730	N732S	732	Missense	proximal	2	no	17.797	17.934	PhosphoSitePlus	COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	Q05682	CALD1	P24941	CDK2	S759	S765F	765	Missense	distal	6	no	13.252	13.232	EPSD	COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	Q05682	CALD1	P24941	CDK2	S789	D785N	785	Missense	distal	-4	no	16.205	15.817	EPSD	COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	P49916	LIG3	P24941	CDK2	T191	A196S	196	Missense	distal	5	no	17.328	17.217	PhosphoSitePlus;EPSD	COSMIC;GDSC;CCLE	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	P49916	LIG3	P24941	CDK2	S210	T204A	204	Missense	distal	-6	no	16.775	16.774	EPSD;PhosphoSitePlus	COSMIC;GDSC;CCLE	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	P49916	LIG3	P24941	CDK2	S242	P243S	243	Missense	proximal	1	no	11.280	0.014	EPSD	COSMIC	8.148	Loss
CMGC_CDK_CDK2_CDK2_ST	P49916	LIG3	P24941	CDK2	S242	G237V	237	Missense	distal	-5	no	11.280	11.231	EPSD	COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	P49916	LIG3	P24941	CDK2	T244	P243S	243	Missense	proximal	-1	no	14.796	14.325	EPSD	COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	P49916	LIG3	P24941	CDK2	T244	G237V	237	Missense	distal	-7	no	14.796	14.491	EPSD	COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	P48634	PRRC2A	P24941	CDK2	T116	P110A	110	Missense	distal	-6	no	10.231	10.230	EPSD	COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	P48634	PRRC2A	P24941	CDK2	T132	P129L	129	Missense	distal	-3	no	14.276	14.205	EPSD	COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	P48634	PRRC2A	P24941	CDK2	S365	S365F	365	Missense	central	0	yes	8.825	0.000	EPSD	COSMIC	8.148	Loss
CMGC_CDK_CDK2_CDK2_ST	P48634	PRRC2A	P24941	CDK2	S365	E368K	368	Missense	distal	3	no	8.825	10.910	EPSD	COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	P48634	PRRC2A	P24941	CDK2	T517	P515L	515	Missense	proximal	-2	no	12.943	12.719	EPSD	COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	P48634	PRRC2A	P24941	CDK2	T517	P512S	512	Missense	distal	-5	no	12.943	12.899	EPSD	COSMIC;GDSC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	P48634	PRRC2A	P24941	CDK2	T610	P608S	608	Missense	proximal	-2	no	12.989	12.338	EPSD	COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	P48634	PRRC2A	P24941	CDK2	T675	S671C	671	Missense	distal	-4	no	12.266	11.159	EPSD	COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	P48634	PRRC2A	P24941	CDK2	T799	P800H	800	Missense	proximal	1	no	14.750	7.991	EPSD	COSMIC	8.148	Loss
CMGC_CDK_CDK2_CDK2_ST	P48634	PRRC2A	P24941	CDK2	S808	A813V	813	Missense	distal	5	no	16.000	15.957	EPSD	COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	P48634	PRRC2A	P24941	CDK2	S808	R811C	811	Missense	distal	3	no	16.000	9.636	EPSD	COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	P48634	PRRC2A	P24941	CDK2	S808	A813S	813	Missense	distal	5	no	16.000	15.889	EPSD	COSMIC;CCLE	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	P48634	PRRC2A	P24941	CDK2	T825	R822G	822	Missense	distal	-3	no	15.990	15.905	EPSD	COSMIC;GDSC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	P48634	PRRC2A	P24941	CDK2	T825	M821L	821	Missense	distal	-4	no	15.990	16.680	EPSD	COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	P48634	PRRC2A	P24941	CDK2	T878	K882N	882	Missense	distal	4	no	15.249	14.827	EPSD	COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	P48634	PRRC2A	P24941	CDK2	T878	K875N	875	Missense	distal	-3	no	15.249	15.310	EPSD	COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	P48634	PRRC2A	P24941	CDK2	T975	D973G	973	Missense	proximal	-2	no	13.110	12.502	EPSD	COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	P48634	PRRC2A	P24941	CDK2	T997	L1003I	1003	Missense	distal	6	no	12.624	12.623	EPSD	COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	P48634	PRRC2A	P24941	CDK2	T997	P998S	998	Missense	proximal	1	no	12.624	1.358	EPSD	COSMIC	8.148	Loss
CMGC_CDK_CDK2_CDK2_ST	P48634	PRRC2A	P24941	CDK2	S1004	G1001R	1001	Missense	distal	-3	no	15.107	15.192	EPSD	COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	P48634	PRRC2A	P24941	CDK2	S1004	L1003I	1003	Missense	proximal	-1	no	15.107	15.269	EPSD	COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	P48634	PRRC2A	P24941	CDK2	S1004	P998S	998	Missense	distal	-6	no	15.107	15.106	EPSD	COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	P48634	PRRC2A	P24941	CDK2	T1108	E1111K	1111	Missense	distal	3	no	9.643	11.728	EPSD	COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	P48634	PRRC2A	P24941	CDK2	T1126	P1119S	1119	Missense	distal	-7	no	12.069	11.889	EPSD	COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	P48634	PRRC2A	P24941	CDK2	S1147	R1152H	1152	Missense	distal	5	no	12.992	12.964	EPSD	COSMIC;GDSC;CCLE	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	P48634	PRRC2A	P24941	CDK2	S1186	P1179S	1179	Missense	distal	-7	no	12.590	12.410	EPSD	COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	P48634	PRRC2A	P24941	CDK2	S1186	C1182Y	1182	Missense	distal	-4	no	12.590	13.807	EPSD	COSMIC;GDSC;CCLE	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	P48634	PRRC2A	P24941	CDK2	S1219	R1223C	1223	Missense	distal	4	no	14.344	13.717	EPSD	COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	P48634	PRRC2A	P24941	CDK2	S1219	S1219Y	1219	Missense	central	0	yes	14.344	0.000	EPSD	COSMIC	8.148	Loss
CMGC_CDK_CDK2_CDK2_ST	P48634	PRRC2A	P24941	CDK2	S1306	A1303D	1303	Missense	distal	-3	no	14.241	14.365	EPSD	COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	P48634	PRRC2A	P24941	CDK2	T1347	A1340G	1340	Missense	distal	-7	no	12.543	12.703	EPSD	COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	P48634	PRRC2A	P24941	CDK2	S1554	K1559E	1559	Missense	distal	5	no	12.805	12.938	EPSD	COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	P48634	PRRC2A	P24941	CDK2	S1554	P1547L	1547	Missense	distal	-7	no	12.805	12.810	EPSD	COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	P48634	PRRC2A	P24941	CDK2	S1671	K1677N	1677	Missense	distal	6	no	12.291	12.286	EPSD	COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	P48634	PRRC2A	P24941	CDK2	S1671	D1673Y	1673	Missense	proximal	2	no	12.291	12.352	EPSD	COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	P48634	PRRC2A	P24941	CDK2	S1691	P1697L	1697	Missense	distal	6	no	10.207	10.209	EPSD	COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	P48634	PRRC2A	P24941	CDK2	T2076	G2070A	2070	Missense	distal	-6	no	15.123	15.120	EPSD	COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	P48634	PRRC2A	P24941	CDK2	T2093	R2089S	2089	Missense	distal	-4	no	13.815	14.413	EPSD	COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	P48634	PRRC2A	P24941	CDK2	T2093	T2096P	2096	Missense	distal	3	no	13.815	13.929	EPSD	COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	P48634	PRRC2A	P24941	CDK2	S2095	T2096P	2096	Missense	proximal	1	no	5.728	15.685	EPSD	COSMIC	8.148	Gain
CMGC_CDK_CDK2_CDK2_ST	P48634	PRRC2A	P24941	CDK2	S2098	T2096P	2096	Missense	proximal	-2	no	9.042	9.075	EPSD	COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	P48634	PRRC2A	P24941	CDK2	S2113	D2107N	2107	Missense	distal	-6	no	12.104	12.105	EPSD	COSMIC;GDSC;CCLE	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	P20248	CCNA2	P24941	CDK2	S154	S154L	154	Missense	central	0	yes	12.572	0.000	PhosphoSitePlus	COSMIC	8.148	Loss
CMGC_CDK_CDK2_CDK2_ST	Q71UM5	RPS27L	P24941	CDK2	S27	L24I	24	Missense	distal	-3	no	15.431	15.522	PhosphoSitePlus	COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	Q71UM5	RPS27L	P24941	CDK2	S27	M33I	33	Missense	distal	6	no	15.431	15.450	PhosphoSitePlus	COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	O95251	KAT7	P24941	CDK2	S57	P58S	58	Missense	proximal	1	no	15.082	3.816	EPSD	COSMIC	8.148	Loss
CMGC_CDK_CDK2_CDK2_ST	O95251	KAT7	P24941	CDK2	T85	P84L	84	Missense	proximal	-1	no	13.330	13.150	EPSD	COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	O95251	KAT7	P24941	CDK2	T85	T88A	88	Missense	distal	3	no	13.330	12.932	EPSD	COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	O95251	KAT7	P24941	CDK2	T88	P84L	84	Missense	distal	-4	no	16.778	16.720	PhosphoSitePlus	COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	O95251	KAT7	P24941	CDK2	T88	T88A	88	Missense	central	0	yes	16.778	0.000	PhosphoSitePlus	COSMIC	8.148	Loss
CMGC_CDK_CDK2_CDK2_ST	O95251	KAT7	P24941	CDK2	T88	R95W	95	Missense	distal	7	no	16.778	17.177	PhosphoSitePlus	COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	O95251	KAT7	P24941	CDK2	S124	E123D	123	Missense	proximal	-1	no	21.068	21.039	EPSD	COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	O95251	KAT7	P24941	CDK2	T128	E123D	123	Missense	distal	-5	no	14.686	14.706	EPSD	COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	O95251	KAT7	P24941	CDK2	T128	P134S	134	Missense	distal	6	no	14.686	14.687	EPSD	COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	O95251	KAT7	P24941	CDK2	S506	G505S	505	Missense	proximal	-1	no	17.327	15.807	EPSD	COSMIC;CCLE	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	O95251	KAT7	P24941	CDK2	S506	S506F	506	Missense	central	0	yes	17.327	0.000	EPSD	COSMIC	8.148	Loss
CMGC_CDK_CDK2_CDK2_ST	O95251	KAT7	P24941	CDK2	S506	R509H	509	Missense	distal	3	no	17.327	16.630	EPSD	COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	O95251	KAT7	P24941	CDK2	S506	E501K	501	Missense	distal	-5	no	17.327	17.292	EPSD	COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	O95251	KAT7	P24941	CDK2	T606	P600S	600	Missense	distal	-6	no	17.421	17.420	EPSD	COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	O95251	KAT7	P24941	CDK2	T606	S601N	601	Missense	distal	-5	no	17.421	17.484	EPSD	COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	O15014	ZNF609	P24941	CDK2	S8	S8C	8	Missense	central	0	yes	8.358	0.000	EPSD	COSMIC;GDSC;CCLE	8.148	Loss
CMGC_CDK_CDK2_CDK2_ST	O15014	ZNF609	P24941	CDK2	S8	V13M	13	Missense	distal	5	no	8.358	8.699	EPSD	COSMIC;GDSC;CCLE	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	O15014	ZNF609	P24941	CDK2	S275	D272G	272	Missense	distal	-3	no	12.468	12.506	EPSD	COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	O15014	ZNF609	P24941	CDK2	S358	P353R	353	Missense	distal	-5	no	12.272	12.319	EPSD	COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	O15014	ZNF609	P24941	CDK2	S358	F355L	355	Missense	distal	-3	no	12.272	12.015	EPSD	COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	O15014	ZNF609	P24941	CDK2	S358	A351V	351	Missense	distal	-7	no	12.272	12.128	EPSD	COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	O15014	ZNF609	P24941	CDK2	S358	P359L	359	Missense	proximal	1	no	12.272	2.452	EPSD	COSMIC	8.148	Loss
CMGC_CDK_CDK2_CDK2_ST	O15014	ZNF609	P24941	CDK2	T381	R374H	374	Missense	distal	-7	no	10.192	9.971	EPSD	COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	O15014	ZNF609	P24941	CDK2	S390	S396G	396	Missense	distal	6	no	8.528	8.515	EPSD	COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	O15014	ZNF609	P24941	CDK2	S390	T395S	395	Missense	distal	5	no	8.528	8.452	EPSD	COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	O15014	ZNF609	P24941	CDK2	S390	S392N	392	Missense	proximal	2	no	8.528	8.391	EPSD	COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	O15014	ZNF609	P24941	CDK2	T395	S396G	396	Missense	proximal	1	no	4.683	8.637	EPSD	COSMIC	8.148	Gain
CMGC_CDK_CDK2_CDK2_ST	O15014	ZNF609	P24941	CDK2	S433	S433G	433	Missense	central	0	yes	13.262	0.000	EPSD	COSMIC	8.148	Loss
CMGC_CDK_CDK2_CDK2_ST	O15014	ZNF609	P24941	CDK2	S491	P498R	498	Missense	distal	7	no	12.135	12.625	EPSD	COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	O15014	ZNF609	P24941	CDK2	S491	L485M	485	Missense	distal	-6	no	12.135	12.142	EPSD	COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	O15014	ZNF609	P24941	CDK2	S491	N488H	488	Missense	distal	-3	no	12.135	12.260	EPSD	COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	O15014	ZNF609	P24941	CDK2	S560	S560F	560	Missense	central	0	yes	16.246	0.000	EPSD	COSMIC	8.148	Loss
CMGC_CDK_CDK2_CDK2_ST	O15014	ZNF609	P24941	CDK2	T566	S560F	560	Missense	distal	-6	no	14.016	14.021	EPSD	COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	O15014	ZNF609	P24941	CDK2	S609	P613H	613	Missense	distal	4	no	8.370	8.133	EPSD	COSMIC	8.148	Loss
CMGC_CDK_CDK2_CDK2_ST	O15014	ZNF609	P24941	CDK2	S698	P696H	696	Missense	proximal	-2	no	14.022	13.012	EPSD	COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	O15014	ZNF609	P24941	CDK2	T722	P723A	723	Missense	proximal	1	no	14.641	0.237	PhosphoSitePlus	COSMIC	8.148	Loss
CMGC_CDK_CDK2_CDK2_ST	O15014	ZNF609	P24941	CDK2	S743	E742K	742	Missense	proximal	-1	no	15.898	15.013	EPSD	COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	O15014	ZNF609	P24941	CDK2	S743	L745V	745	Missense	proximal	2	no	15.898	16.128	EPSD	COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	O15014	ZNF609	P24941	CDK2	S743	S738L	738	Missense	distal	-5	no	15.898	15.955	EPSD	COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	O15014	ZNF609	P24941	CDK2	T746	E742K	742	Missense	distal	-4	no	17.951	17.640	EPSD	COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	O15014	ZNF609	P24941	CDK2	T746	L745V	745	Missense	proximal	-1	no	17.951	18.088	EPSD	COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	O15014	ZNF609	P24941	CDK2	S758	P759S	759	Missense	proximal	1	no	15.035	3.770	EPSD	COSMIC	8.148	Loss
CMGC_CDK_CDK2_CDK2_ST	O15014	ZNF609	P24941	CDK2	S758	R761K	761	Missense	distal	3	no	15.035	16.024	EPSD	COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	O15014	ZNF609	P24941	CDK2	S758	G756C	756	Missense	proximal	-2	no	15.035	14.716	EPSD	COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	O15014	ZNF609	P24941	CDK2	S804	G809D	809	Missense	distal	5	no	13.908	13.955	EPSD	COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	O15014	ZNF609	P24941	CDK2	T823	Q830R	830	Missense	distal	7	no	16.245	16.890	EPSD	COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	O15014	ZNF609	P24941	CDK2	S842	S849F	849	Missense	distal	7	no	13.495	14.349	EPSD	COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	O15014	ZNF609	P24941	CDK2	S1105	K1100N	1100	Missense	distal	-5	no	8.500	8.516	EPSD	COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	O15014	ZNF609	P24941	CDK2	S1267	S1267F	1267	Missense	central	0	yes	13.626	0.000	EPSD	COSMIC	8.148	Loss
CMGC_CDK_CDK2_CDK2_ST	O15014	ZNF609	P24941	CDK2	S1267	G1270D	1270	Missense	distal	3	no	13.626	11.914	EPSD	COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	O15014	ZNF609	P24941	CDK2	S1285	S1285N	1285	Missense	central	0	yes	13.880	0.000	EPSD	COSMIC	8.148	Loss
CMGC_CDK_CDK2_CDK2_ST	O15014	ZNF609	P24941	CDK2	S1357	R1353Q	1353	Missense	distal	-4	no	12.275	12.300	EPSD	COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	O15014	ZNF609	P24941	CDK2	S1357	R1355C	1355	Missense	proximal	-2	no	12.275	12.449	EPSD	COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	P17706	PTPN2	P24941	CDK2	S52	Y54C	54	Missense	proximal	2	no	12.359	12.447	EPSD	COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	P17706	PTPN2	P24941	CDK2	S52	R45Q	45	Missense	distal	-7	no	12.359	11.973	EPSD	COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	P17706	PTPN2	P24941	CDK2	S52	R58H	58	Missense	distal	6	no	12.359	12.370	EPSD	COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	P17706	PTPN2	P24941	CDK2	S52	R49K	49	Missense	distal	-3	no	12.359	12.130	EPSD	COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	P17706	PTPN2	P24941	CDK2	S57	R58H	58	Missense	proximal	1	no	6.148	9.188	EPSD	COSMIC	8.148	Gain
CMGC_CDK_CDK2_CDK2_ST	P17706	PTPN2	P24941	CDK2	T261	R255Q	255	Missense	distal	-6	no	11.726	11.727	EPSD	COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	P17706	PTPN2	P24941	CDK2	T261	L258W	258	Missense	distal	-3	no	11.726	12.066	EPSD	COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	P17706	PTPN2	P24941	CDK2	T261	D263N	263	Missense	proximal	2	no	11.726	11.658	EPSD	COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	P17706	PTPN2	P24941	CDK2	S298	D302V	302	Missense	distal	4	no	12.980	13.272	EPSD	COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	P17706	PTPN2	P24941	CDK2	S298	P299L	299	Missense	proximal	1	no	12.980	3.159	EPSD	COSMIC	8.148	Loss
CMGC_CDK_CDK2_CDK2_ST	P17706	PTPN2	P24941	CDK2	S298	D302G	302	Missense	distal	4	no	12.980	12.925	EPSD	COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	P17706	PTPN2	P24941	CDK2	S304	D302V	302	Missense	proximal	-2	no	19.445	18.930	PhosphoSitePlus	COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	P17706	PTPN2	P24941	CDK2	S304	M309R	309	Missense	distal	5	no	19.445	19.244	PhosphoSitePlus	COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	P17706	PTPN2	P24941	CDK2	S304	P299L	299	Missense	distal	-5	no	19.445	19.457	PhosphoSitePlus	COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	P17706	PTPN2	P24941	CDK2	S304	D302G	302	Missense	proximal	-2	no	19.445	18.838	PhosphoSitePlus	COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	Q9Y3Z3	SAMHD1	P24941	CDK2	T25	A30T	30	Missense	distal	5	no	13.338	13.302	EPSD	COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	Q9Y3Z3	SAMHD1	P24941	CDK2	S33	A30T	30	Missense	distal	-3	no	14.172	14.191	EPSD	COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	Q9Y3Z3	SAMHD1	P24941	CDK2	T138	L132I	132	Missense	distal	-6	no	15.462	15.464	EPSD	COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	Q9Y3Z3	SAMHD1	P24941	CDK2	S278	E277K	277	Missense	proximal	-1	no	14.555	13.670	EPSD	COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	Q9Y3Z3	SAMHD1	P24941	CDK2	S278	G274E	274	Missense	distal	-4	no	14.555	15.103	EPSD	COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	Q9Y3Z3	SAMHD1	P24941	CDK2	T592	P593S	593	Missense	proximal	1	no	17.916	6.650	PhosphoSitePlus	COSMIC	8.148	Loss
CMGC_CDK_CDK2_CDK2_ST	Q9Y3Z3	SAMHD1	P24941	CDK2	T592	I587V	587	Missense	distal	-5	no	17.916	17.907	PhosphoSitePlus	COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	O14497	ARID1A	P24941	CDK2	S90	P94L	94	Missense	distal	4	no	9.220	9.332	EPSD	COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	O14497	ARID1A	P24941	CDK2	S90	G83D	83	Missense	distal	-7	no	9.220	9.137	EPSD	COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	O14497	ARID1A	P24941	CDK2	S90	A88P	88	Missense	proximal	-2	no	9.220	9.204	EPSD	COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	O14497	ARID1A	P24941	CDK2	S90	G89R	89	Missense	proximal	-1	no	9.220	8.742	EPSD	COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	O14497	ARID1A	P24941	CDK2	S157	A163T	163	Missense	distal	6	no	13.586	13.598	EPSD	COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	O14497	ARID1A	P24941	CDK2	S157	P153A	153	Missense	distal	-4	no	13.586	13.527	EPSD	COSMIC;CCLE	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	O14497	ARID1A	P24941	CDK2	S157	A164T	164	Missense	distal	7	no	13.586	12.897	EPSD	COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	O14497	ARID1A	P24941	CDK2	S157	A163V	163	Missense	distal	6	no	13.586	13.589	EPSD	COSMIC;CCLE	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	O14497	ARID1A	P24941	CDK2	S157	P153L	153	Missense	distal	-4	no	13.586	13.528	EPSD	COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	O14497	ARID1A	P24941	CDK2	S157	Y154H	154	Missense	distal	-3	no	13.586	13.618	EPSD	COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	O14497	ARID1A	P24941	CDK2	S157	V161A	161	Missense	distal	4	no	13.586	13.399	EPSD	COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	O14497	ARID1A	P24941	CDK2	S233	G236D	236	Missense	distal	3	no	13.642	11.929	EPSD	COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	O14497	ARID1A	P24941	CDK2	S233	P239A	239	Missense	distal	6	no	13.642	13.637	EPSD	COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	O14497	ARID1A	P24941	CDK2	S233	P227Q	227	Missense	distal	-6	no	13.642	13.644	EPSD	COSMIC;CCLE	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	O14497	ARID1A	P24941	CDK2	S233	G237D	237	Missense	distal	4	no	13.642	13.696	EPSD	COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	O14497	ARID1A	P24941	CDK2	S233	G240R	240	Missense	distal	7	no	13.642	13.461	EPSD	COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	O14497	ARID1A	P24941	CDK2	S233	A226P	226	Missense	distal	-7	no	13.642	13.477	EPSD	COSMIC;CCLE	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	O14497	ARID1A	P24941	CDK2	T238	G236D	236	Missense	proximal	-2	no	12.964	13.572	EPSD	COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	O14497	ARID1A	P24941	CDK2	T238	A245S	245	Missense	distal	7	no	12.964	12.427	EPSD	COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	O14497	ARID1A	P24941	CDK2	T238	P239A	239	Missense	proximal	1	no	12.964	-1.439	EPSD	COSMIC	8.148	Loss
CMGC_CDK_CDK2_CDK2_ST	O14497	ARID1A	P24941	CDK2	T238	A243G	243	Missense	distal	5	no	12.964	13.081	EPSD	COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	O14497	ARID1A	P24941	CDK2	T238	S241C	241	Missense	distal	3	no	12.964	8.284	EPSD	COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	O14497	ARID1A	P24941	CDK2	T238	G237D	237	Missense	proximal	-1	no	12.964	12.671	EPSD	COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	O14497	ARID1A	P24941	CDK2	T238	S241F	241	Missense	distal	3	no	12.964	12.889	EPSD	COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	O14497	ARID1A	P24941	CDK2	T238	G240R	240	Missense	proximal	2	no	12.964	13.005	EPSD	COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	O14497	ARID1A	P24941	CDK2	T286	A281S	281	Missense	distal	-5	no	14.583	14.514	EPSD	COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	O14497	ARID1A	P24941	CDK2	T286	P287L	287	Missense	proximal	1	no	14.583	4.762	EPSD	COSMIC	8.148	Loss
CMGC_CDK_CDK2_CDK2_ST	O14497	ARID1A	P24941	CDK2	T286	P289S	289	Missense	distal	3	no	14.583	14.617	EPSD	COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	O14497	ARID1A	P24941	CDK2	T286	T290I	290	Missense	distal	4	no	14.583	14.272	EPSD	COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	O14497	ARID1A	P24941	CDK2	T286	P293S	293	Missense	distal	7	no	14.583	14.431	EPSD	COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	O14497	ARID1A	P24941	CDK2	T286	P293L	293	Missense	distal	7	no	14.583	14.613	EPSD	COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	O14497	ARID1A	P24941	CDK2	T292	T294P	294	Missense	proximal	2	no	14.197	14.375	EPSD	COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	O14497	ARID1A	P24941	CDK2	T292	P287L	287	Missense	distal	-5	no	14.197	14.209	EPSD	COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	O14497	ARID1A	P24941	CDK2	T292	P289S	289	Missense	distal	-3	no	14.197	14.292	EPSD	COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	O14497	ARID1A	P24941	CDK2	T292	T290I	290	Missense	proximal	-2	no	14.197	14.076	EPSD	COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	O14497	ARID1A	P24941	CDK2	T292	P293S	293	Missense	proximal	1	no	14.197	2.931	EPSD	COSMIC	8.148	Loss
CMGC_CDK_CDK2_CDK2_ST	O14497	ARID1A	P24941	CDK2	T292	P293L	293	Missense	proximal	1	no	14.197	4.376	EPSD	COSMIC	8.148	Loss
CMGC_CDK_CDK2_CDK2_ST	O14497	ARID1A	P24941	CDK2	S301	T294P	294	Missense	distal	-7	no	15.027	15.030	EPSD	COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	O14497	ARID1A	P24941	CDK2	S301	S303R	303	Missense	proximal	2	no	15.027	15.119	EPSD	COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	O14497	ARID1A	P24941	CDK2	S317	D322E	322	Missense	distal	5	no	8.926	8.832	EPSD	COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	O14497	ARID1A	P24941	CDK2	S317	S317N	317	Missense	central	0	yes	8.926	0.000	EPSD	COSMIC	8.148	Loss
CMGC_CDK_CDK2_CDK2_ST	O14497	ARID1A	P24941	CDK2	S317	G313K	313	Missense	distal	-4	no	8.926	9.163	EPSD	COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	O14497	ARID1A	P24941	CDK2	S317	G313V	313	Missense	distal	-4	no	8.926	9.196	EPSD	COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	O14497	ARID1A	P24941	CDK2	S317	G318C	318	Missense	proximal	1	no	8.926	-2.691	EPSD	COSMIC	8.148	Loss
CMGC_CDK_CDK2_CDK2_ST	O14497	ARID1A	P24941	CDK2	S317	G318A	318	Missense	proximal	1	no	8.926	1.835	EPSD	COSMIC	8.148	Loss
CMGC_CDK_CDK2_CDK2_ST	O14497	ARID1A	P24941	CDK2	S317	P320F	320	Missense	distal	3	no	8.926	8.885	EPSD	COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	O14497	ARID1A	P24941	CDK2	S363	G365E	365	Missense	proximal	2	no	17.004	16.983	PhosphoSitePlus	COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	O14497	ARID1A	P24941	CDK2	S363	R356S	356	Missense	distal	-7	no	17.004	16.480	PhosphoSitePlus	COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	O14497	ARID1A	P24941	CDK2	S363	S357F	357	Missense	distal	-6	no	17.004	17.009	PhosphoSitePlus	COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	O14497	ARID1A	P24941	CDK2	S363	S357P	357	Missense	distal	-6	no	17.004	17.005	PhosphoSitePlus	COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	O14497	ARID1A	P24941	CDK2	T377	S381P	381	Missense	distal	4	no	15.467	15.453	EPSD	COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	O14497	ARID1A	P24941	CDK2	T377	S381C	381	Missense	distal	4	no	15.467	14.706	EPSD	COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	O14497	ARID1A	P24941	CDK2	T377	P383L	383	Missense	distal	6	no	15.467	15.468	EPSD	COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	O14497	ARID1A	P24941	CDK2	T377	P380T	380	Missense	distal	3	no	15.467	15.353	EPSD	COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	O14497	ARID1A	P24941	CDK2	T377	Q379E	379	Missense	proximal	2	no	15.467	15.504	EPSD	COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	O14497	ARID1A	P24941	CDK2	T377	S381F	381	Missense	distal	4	no	15.467	15.271	EPSD	COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	O14497	ARID1A	P24941	CDK2	S382	S381P	381	Missense	proximal	-1	no	12.096	12.567	EPSD	COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	O14497	ARID1A	P24941	CDK2	S382	S381C	381	Missense	proximal	-1	no	12.096	12.440	EPSD	COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	O14497	ARID1A	P24941	CDK2	S382	P383L	383	Missense	proximal	1	no	12.096	2.275	EPSD	COSMIC	8.148	Loss
CMGC_CDK_CDK2_CDK2_ST	O14497	ARID1A	P24941	CDK2	S382	G388D	388	Missense	distal	6	no	12.096	12.092	EPSD	COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	O14497	ARID1A	P24941	CDK2	S382	P380T	380	Missense	proximal	-2	no	12.096	12.063	EPSD	COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	O14497	ARID1A	P24941	CDK2	S382	G388S	388	Missense	distal	6	no	12.096	12.109	EPSD	COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	O14497	ARID1A	P24941	CDK2	S382	Q379E	379	Missense	distal	-3	no	12.096	12.213	EPSD	COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	O14497	ARID1A	P24941	CDK2	S382	S381F	381	Missense	proximal	-1	no	12.096	13.353	EPSD	COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	O14497	ARID1A	P24941	CDK2	S613	S614P	614	Missense	proximal	1	no	1.365	12.631	EPSD	COSMIC	8.148	Gain
CMGC_CDK_CDK2_CDK2_ST	O14497	ARID1A	P24941	CDK2	S658	S662G	662	Missense	distal	4	no	15.491	15.357	EPSD	COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	O14497	ARID1A	P24941	CDK2	S658	P659L	659	Missense	proximal	1	no	15.491	5.670	EPSD	COSMIC	8.148	Loss
CMGC_CDK_CDK2_CDK2_ST	O14497	ARID1A	P24941	CDK2	S658	G652R	652	Missense	distal	-6	no	15.491	15.490	EPSD	COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	O14497	ARID1A	P24941	CDK2	S658	T663S	663	Missense	distal	5	no	15.491	15.416	EPSD	COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	O14497	ARID1A	P24941	CDK2	S682	P680L	680	Missense	proximal	-2	no	11.289	11.064	EPSD	COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	O14497	ARID1A	P24941	CDK2	S682	P676S	676	Missense	distal	-6	no	11.289	11.288	EPSD	COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	O14497	ARID1A	P24941	CDK2	S682	F681L	681	Missense	proximal	-1	no	11.289	10.323	EPSD	COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	O14497	ARID1A	P24941	CDK2	S682	P683L	683	Missense	proximal	1	no	11.289	1.468	EPSD	COSMIC	8.148	Loss
CMGC_CDK_CDK2_CDK2_ST	O14497	ARID1A	P24941	CDK2	S682	H688P	688	Missense	distal	6	no	11.289	11.293	EPSD	COSMIC;GDSC;CCLE	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	O14497	ARID1A	P24941	CDK2	S696	P697L	697	Missense	proximal	1	no	13.124	3.303	EPSD	COSMIC;CCLE	8.148	Loss
CMGC_CDK_CDK2_CDK2_ST	O14497	ARID1A	P24941	CDK2	S696	P703F	703	Missense	distal	7	no	13.124	13.825	EPSD	COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	O14497	ARID1A	P24941	CDK2	S696	S696F	696	Missense	central	0	yes	13.124	0.000	EPSD	COSMIC	8.148	Loss
CMGC_CDK_CDK2_CDK2_ST	O14497	ARID1A	P24941	CDK2	S696	G701A	701	Missense	distal	5	no	13.124	13.007	EPSD	COSMIC;GDSC;CCLE	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	O14497	ARID1A	P24941	CDK2	S696	P699S	699	Missense	distal	3	no	13.124	13.158	EPSD	COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	O14497	ARID1A	P24941	CDK2	S696	P697S	697	Missense	proximal	1	no	13.124	1.858	EPSD	COSMIC	8.148	Loss
CMGC_CDK_CDK2_CDK2_ST	O14497	ARID1A	P24941	CDK2	S696	I692V	692	Missense	distal	-4	no	13.124	13.227	EPSD	COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	O14497	ARID1A	P24941	CDK2	S696	R693Q	693	Missense	distal	-3	no	13.124	12.993	EPSD	COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	O14497	ARID1A	P24941	CDK2	S698	P697L	697	Missense	proximal	-1	no	11.860	11.681	EPSD	COSMIC;CCLE	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	O14497	ARID1A	P24941	CDK2	S698	P703F	703	Missense	distal	5	no	11.860	12.078	EPSD	COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	O14497	ARID1A	P24941	CDK2	S698	S696F	696	Missense	proximal	-2	no	11.860	11.398	EPSD	COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	O14497	ARID1A	P24941	CDK2	S698	S705C	705	Missense	distal	7	no	11.860	12.653	EPSD	COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	O14497	ARID1A	P24941	CDK2	S698	G701A	701	Missense	distal	3	no	11.860	11.449	EPSD	COSMIC;GDSC;CCLE	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	O14497	ARID1A	P24941	CDK2	S698	P699S	699	Missense	proximal	1	no	11.860	0.594	EPSD	COSMIC	8.148	Loss
CMGC_CDK_CDK2_CDK2_ST	O14497	ARID1A	P24941	CDK2	S698	P697S	697	Missense	proximal	-1	no	11.860	11.389	EPSD	COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	O14497	ARID1A	P24941	CDK2	S698	R693Q	693	Missense	distal	-5	no	11.860	11.814	EPSD	COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	O14497	ARID1A	P24941	CDK2	S698	A704T	704	Missense	distal	6	no	11.860	11.872	EPSD	COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	O14497	ARID1A	P24941	CDK2	S702	P697L	697	Missense	distal	-5	no	13.388	13.399	EPSD	COSMIC;CCLE	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	O14497	ARID1A	P24941	CDK2	S702	Q708P	708	Missense	distal	6	no	13.388	13.382	EPSD	COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	O14497	ARID1A	P24941	CDK2	S702	P703F	703	Missense	proximal	1	no	13.388	-1.422	EPSD	COSMIC	8.148	Loss
CMGC_CDK_CDK2_CDK2_ST	O14497	ARID1A	P24941	CDK2	S702	S696F	696	Missense	distal	-6	no	13.388	13.393	EPSD	COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	O14497	ARID1A	P24941	CDK2	S702	S705C	705	Missense	distal	3	no	13.388	8.708	EPSD	COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	O14497	ARID1A	P24941	CDK2	S702	G701A	701	Missense	proximal	-1	no	13.388	12.069	EPSD	COSMIC;GDSC;CCLE	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	O14497	ARID1A	P24941	CDK2	S702	P699S	699	Missense	distal	-3	no	13.388	13.483	EPSD	COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	O14497	ARID1A	P24941	CDK2	S702	P697S	697	Missense	distal	-5	no	13.388	13.343	EPSD	COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	O14497	ARID1A	P24941	CDK2	S702	A704T	704	Missense	proximal	2	no	13.388	13.186	EPSD	COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	O14497	ARID1A	P24941	CDK2	S715	Q708P	708	Missense	distal	-7	no	14.829	14.872	EPSD	COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	O14497	ARID1A	P24941	CDK2	S715	N722D	722	Missense	distal	7	no	14.829	15.609	EPSD	COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	O14497	ARID1A	P24941	CDK2	S715	L714I	714	Missense	proximal	-1	no	14.829	14.992	EPSD	COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	O14497	ARID1A	P24941	CDK2	S715	N722K	722	Missense	distal	7	no	14.829	14.636	EPSD	COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	O14497	ARID1A	P24941	CDK2	S715	G721R	721	Missense	distal	6	no	14.829	14.824	EPSD	COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	O14497	ARID1A	P24941	CDK2	S764	Q766E	766	Missense	proximal	2	no	14.114	14.152	EPSD	COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	O14497	ARID1A	P24941	CDK2	S764	Q766H	766	Missense	proximal	2	no	14.114	14.133	EPSD	COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	O14497	ARID1A	P24941	CDK2	S764	M759I	759	Missense	distal	-5	no	14.114	14.047	EPSD	COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	O14497	ARID1A	P24941	CDK2	S764	S763F	763	Missense	proximal	-1	no	14.114	15.371	EPSD	COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	O14497	ARID1A	P24941	CDK2	S764	S764F	764	Missense	central	0	yes	14.114	0.000	EPSD	COSMIC;GDSC;CCLE	8.148	Loss
CMGC_CDK_CDK2_CDK2_ST	O14497	ARID1A	P24941	CDK2	S764	G768S	768	Missense	distal	4	no	14.114	14.248	EPSD	COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	O14497	ARID1A	P24941	CDK2	S764	P760S	760	Missense	distal	-4	no	14.114	14.469	EPSD	COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	O14497	ARID1A	P24941	CDK2	S772	Q766E	766	Missense	distal	-6	no	13.634	13.633	EPSD	COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	O14497	ARID1A	P24941	CDK2	S772	P773S	773	Missense	proximal	1	no	13.634	2.368	EPSD	COSMIC;CCLE	8.148	Loss
CMGC_CDK_CDK2_CDK2_ST	O14497	ARID1A	P24941	CDK2	S772	G768S	768	Missense	distal	-4	no	13.634	14.306	EPSD	COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	O14497	ARID1A	P24941	CDK2	S772	P776R	776	Missense	distal	4	no	13.634	13.513	EPSD	COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	O14497	ARID1A	P24941	CDK2	S772	P776A	776	Missense	distal	4	no	13.634	13.673	EPSD	COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	O14497	ARID1A	P24941	CDK2	S777	G784V	784	Missense	distal	7	no	8.248	7.836	EPSD	COSMIC	8.148	Loss
CMGC_CDK_CDK2_CDK2_ST	O14497	ARID1A	P24941	CDK2	S777	P773S	773	Missense	distal	-4	no	8.248	8.602	EPSD	COSMIC;CCLE	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	O14497	ARID1A	P24941	CDK2	S777	P776R	776	Missense	proximal	-1	no	8.248	8.818	EPSD	COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	O14497	ARID1A	P24941	CDK2	S777	P776A	776	Missense	proximal	-1	no	8.248	7.977	EPSD	COSMIC	8.148	Loss
CMGC_CDK_CDK2_CDK2_ST	O14497	ARID1A	P24941	CDK2	S964	A962V	962	Missense	proximal	-2	no	14.072	13.406	EPSD	COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	O14497	ARID1A	P24941	CDK2	S964	A962T	962	Missense	proximal	-2	no	14.072	14.022	EPSD	COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	O14497	ARID1A	P24941	CDK2	S964	N957K	957	Missense	distal	-7	no	14.072	14.106	EPSD	COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	O14497	ARID1A	P24941	CDK2	S964	P965L	965	Missense	proximal	1	no	14.072	4.251	EPSD	COSMIC	8.148	Loss
CMGC_CDK_CDK2_CDK2_ST	O14497	ARID1A	P24941	CDK2	T976	M981I	981	Missense	distal	5	no	12.578	12.363	EPSD	COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	O14497	ARID1A	P24941	CDK2	T976	T979I	979	Missense	distal	3	no	12.578	12.025	EPSD	COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	O14497	ARID1A	P24941	CDK2	T976	N983S	983	Missense	distal	7	no	12.578	12.520	EPSD	COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	O14497	ARID1A	P24941	CDK2	T976	A978V	978	Missense	proximal	2	no	12.578	12.676	EPSD	COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	O14497	ARID1A	P24941	CDK2	T976	T976I	976	Missense	central	0	yes	12.578	0.000	EPSD	COSMIC	8.148	Loss
CMGC_CDK_CDK2_CDK2_ST	O14497	ARID1A	P24941	CDK2	T988	M981I	981	Missense	distal	-7	no	15.460	15.153	EPSD	COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	O14497	ARID1A	P24941	CDK2	T988	N983S	983	Missense	distal	-5	no	15.460	15.396	EPSD	COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	O14497	ARID1A	P24941	CDK2	T988	K990Q	990	Missense	proximal	2	no	15.460	15.660	EPSD	COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	O14497	ARID1A	P24941	CDK2	T988	P989S	989	Missense	proximal	1	no	15.460	4.194	EPSD	COSMIC	8.148	Loss
CMGC_CDK_CDK2_CDK2_ST	O14497	ARID1A	P24941	CDK2	S1091	A1088V	1088	Missense	distal	-3	no	8.131	8.332	EPSD	COSMIC	8.148	Gain
CMGC_CDK_CDK2_CDK2_ST	O14497	ARID1A	P24941	CDK2	S1126	K1129E	1129	Missense	distal	3	no	10.976	8.890	EPSD	COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	O14497	ARID1A	P24941	CDK2	S1126	K1129T	1129	Missense	distal	3	no	10.976	8.154	EPSD	COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	O14497	ARID1A	P24941	CDK2	S1126	K1125N	1125	Missense	proximal	-1	no	10.976	11.003	EPSD	COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	O14497	ARID1A	P24941	CDK2	S1126	P1133T	1133	Missense	distal	7	no	10.976	10.672	EPSD	COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	O14497	ARID1A	P24941	CDK2	S1134	P1135L	1135	Missense	proximal	1	no	14.090	4.269	EPSD	COSMIC	8.148	Loss
CMGC_CDK_CDK2_CDK2_ST	O14497	ARID1A	P24941	CDK2	S1134	S1134C	1134	Missense	central	0	yes	14.090	0.000	EPSD	COSMIC	8.148	Loss
CMGC_CDK_CDK2_CDK2_ST	O14497	ARID1A	P24941	CDK2	S1134	K1129E	1129	Missense	distal	-5	no	14.090	14.124	EPSD	COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	O14497	ARID1A	P24941	CDK2	S1134	K1129T	1129	Missense	distal	-5	no	14.090	14.086	EPSD	COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	O14497	ARID1A	P24941	CDK2	S1134	P1135S	1135	Missense	proximal	1	no	14.090	2.824	EPSD	COSMIC	8.148	Loss
CMGC_CDK_CDK2_CDK2_ST	O14497	ARID1A	P24941	CDK2	S1134	P1133T	1133	Missense	proximal	-1	no	14.090	13.827	EPSD	COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	O14497	ARID1A	P24941	CDK2	S1134	G1137D	1137	Missense	distal	3	no	14.090	12.377	EPSD	COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	O14497	ARID1A	P24941	CDK2	S1134	A1136T	1136	Missense	proximal	2	no	14.090	13.888	EPSD	COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	O14497	ARID1A	P24941	CDK2	S1134	A1136V	1136	Missense	proximal	2	no	14.090	14.188	EPSD	COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	O14497	ARID1A	P24941	CDK2	S1138	P1135L	1135	Missense	distal	-3	no	8.788	8.717	EPSD	COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	O14497	ARID1A	P24941	CDK2	S1138	S1134C	1134	Missense	distal	-4	no	8.788	7.682	EPSD	COSMIC	8.148	Loss
CMGC_CDK_CDK2_CDK2_ST	O14497	ARID1A	P24941	CDK2	S1138	P1135S	1135	Missense	distal	-3	no	8.788	8.883	EPSD	COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	O14497	ARID1A	P24941	CDK2	S1138	P1133T	1133	Missense	distal	-5	no	8.788	8.787	EPSD	COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	O14497	ARID1A	P24941	CDK2	S1138	G1137D	1137	Missense	proximal	-1	no	8.788	8.495	EPSD	COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	O14497	ARID1A	P24941	CDK2	S1138	A1136T	1136	Missense	proximal	-2	no	8.788	8.739	EPSD	COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	O14497	ARID1A	P24941	CDK2	S1138	A1136V	1136	Missense	proximal	-2	no	8.788	8.122	EPSD	COSMIC	8.148	Loss
CMGC_CDK_CDK2_CDK2_ST	O14497	ARID1A	P24941	CDK2	T1146	S1151N	1151	Missense	distal	5	no	13.026	13.230	EPSD	COSMIC;GDSC;CCLE	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	O14497	ARID1A	P24941	CDK2	T1146	P1147L	1147	Missense	proximal	1	no	13.026	3.205	EPSD	COSMIC	8.148	Loss
CMGC_CDK_CDK2_CDK2_ST	O14497	ARID1A	P24941	CDK2	T1164	H1170P	1170	Missense	distal	6	no	14.470	14.475	EPSD	COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	O14497	ARID1A	P24941	CDK2	T1164	G1157E	1157	Missense	distal	-7	no	14.470	14.236	EPSD	COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	O14497	ARID1A	P24941	CDK2	T1164	S1167A	1167	Missense	distal	3	no	14.470	13.924	EPSD	COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	O14497	ARID1A	P24941	CDK2	T1164	A1166S	1166	Missense	proximal	2	no	14.470	14.512	EPSD	COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	O14497	ARID1A	P24941	CDK2	T1164	P1169L	1169	Missense	distal	5	no	14.470	14.510	EPSD	COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	O14497	ARID1A	P24941	CDK2	T1164	P1163L	1163	Missense	proximal	-1	no	14.470	14.290	EPSD	COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	O14497	ARID1A	P24941	CDK2	T1164	T1164P	1164	Missense	central	0	yes	14.470	0.000	EPSD	COSMIC	8.148	Loss
CMGC_CDK_CDK2_CDK2_ST	O14497	ARID1A	P24941	CDK2	T1164	P1169S	1169	Missense	distal	5	no	14.470	14.369	EPSD	COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	O14497	ARID1A	P24941	CDK2	T1164	P1162L	1162	Missense	proximal	-2	no	14.470	14.246	EPSD	COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	O14497	ARID1A	P24941	CDK2	T1164	G1157A	1157	Missense	distal	-7	no	14.470	14.310	EPSD	COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	O14497	ARID1A	P24941	CDK2	T1168	H1170P	1170	Missense	proximal	2	no	13.398	13.320	EPSD	COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	O14497	ARID1A	P24941	CDK2	T1168	S1167A	1167	Missense	proximal	-1	no	13.398	13.598	EPSD	COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	O14497	ARID1A	P24941	CDK2	T1168	A1166S	1166	Missense	proximal	-2	no	13.398	12.730	EPSD	COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	O14497	ARID1A	P24941	CDK2	T1168	P1169L	1169	Missense	proximal	1	no	13.398	3.577	EPSD	COSMIC	8.148	Loss
CMGC_CDK_CDK2_CDK2_ST	O14497	ARID1A	P24941	CDK2	T1168	P1163L	1163	Missense	distal	-5	no	13.398	13.409	EPSD	COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	O14497	ARID1A	P24941	CDK2	T1168	T1164P	1164	Missense	distal	-4	no	13.398	13.231	EPSD	COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	O14497	ARID1A	P24941	CDK2	T1168	P1175Q	1175	Missense	distal	7	no	13.398	13.243	EPSD	COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	O14497	ARID1A	P24941	CDK2	T1168	P1169S	1169	Missense	proximal	1	no	13.398	2.132	EPSD	COSMIC	8.148	Loss
CMGC_CDK_CDK2_CDK2_ST	O14497	ARID1A	P24941	CDK2	T1168	P1174S	1174	Missense	distal	6	no	13.398	13.399	EPSD	COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	O14497	ARID1A	P24941	CDK2	S1171	H1170P	1170	Missense	proximal	-1	no	8.460	8.340	EPSD	COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	O14497	ARID1A	P24941	CDK2	S1171	S1167A	1167	Missense	distal	-4	no	8.460	8.046	EPSD	COSMIC	8.148	Loss
CMGC_CDK_CDK2_CDK2_ST	O14497	ARID1A	P24941	CDK2	S1171	A1166S	1166	Missense	distal	-5	no	8.460	8.390	EPSD	COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	O14497	ARID1A	P24941	CDK2	S1171	P1169L	1169	Missense	proximal	-2	no	8.460	8.235	EPSD	COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	O14497	ARID1A	P24941	CDK2	S1171	T1164P	1164	Missense	distal	-7	no	8.460	8.462	EPSD	COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	O14497	ARID1A	P24941	CDK2	S1171	G1178A	1178	Missense	distal	7	no	8.460	8.174	EPSD	COSMIC;GDSC;CCLE	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	O14497	ARID1A	P24941	CDK2	S1171	P1175Q	1175	Missense	distal	4	no	8.460	8.521	EPSD	COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	O14497	ARID1A	P24941	CDK2	S1171	P1169S	1169	Missense	proximal	-2	no	8.460	7.808	EPSD	COSMIC	8.148	Loss
CMGC_CDK_CDK2_CDK2_ST	O14497	ARID1A	P24941	CDK2	S1171	P1174S	1174	Missense	distal	3	no	8.460	8.494	EPSD	COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	O14497	ARID1A	P24941	CDK2	S1195	R1202W	1202	Missense	distal	7	no	7.820	8.220	EPSD	COSMIC	8.148	Gain
CMGC_CDK_CDK2_CDK2_ST	O14497	ARID1A	P24941	CDK2	S1195	D1196G	1196	Missense	proximal	1	no	7.820	8.752	EPSD	COSMIC	8.148	Gain
CMGC_CDK_CDK2_CDK2_ST	O14497	ARID1A	P24941	CDK2	T1206	R1202W	1202	Missense	distal	-4	no	16.056	15.298	EPSD	COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	O14497	ARID1A	P24941	CDK2	T1206	T1206I	1206	Missense	central	0	yes	16.056	0.000	EPSD	COSMIC	8.148	Loss
CMGC_CDK_CDK2_CDK2_ST	O14497	ARID1A	P24941	CDK2	T1206	Q1212E	1212	Missense	distal	6	no	16.056	16.047	EPSD	COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	O14497	ARID1A	P24941	CDK2	T1206	Q1212L	1212	Missense	distal	6	no	16.056	16.052	EPSD	COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	O14497	ARID1A	P24941	CDK2	T1206	R1202Q	1202	Missense	distal	-4	no	16.056	16.081	EPSD	COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	O14497	ARID1A	P24941	CDK2	T1206	S1204F	1204	Missense	proximal	-2	no	16.056	15.594	EPSD	COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	O14497	ARID1A	P24941	CDK2	T1206	Q1200R	1200	Missense	distal	-6	no	16.056	16.055	EPSD	COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	O14497	ARID1A	P24941	CDK2	T1206	Q1200L	1200	Missense	distal	-6	no	16.056	16.053	EPSD	COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	O14497	ARID1A	P24941	CDK2	T1206	P1209S	1209	Missense	distal	3	no	16.056	16.090	EPSD	COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	O14497	ARID1A	P24941	CDK2	T1206	P1207L	1207	Missense	proximal	1	no	16.056	6.235	EPSD	COSMIC	8.148	Loss
CMGC_CDK_CDK2_CDK2_ST	O14497	ARID1A	P24941	CDK2	S1316	N1313S	1313	Missense	distal	-3	no	8.789	8.864	EPSD	COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	O14497	ARID1A	P24941	CDK2	S1316	R1323C	1323	Missense	distal	7	no	8.789	8.940	EPSD	COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	O14497	ARID1A	P24941	CDK2	S1316	R1323H	1323	Missense	distal	7	no	8.789	8.431	EPSD	COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	O14497	ARID1A	P24941	CDK2	S1316	D1315G	1315	Missense	proximal	-1	no	8.789	9.082	EPSD	COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	O14497	ARID1A	P24941	CDK2	S1320	N1313S	1313	Missense	distal	-7	no	15.061	14.963	EPSD	COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	O14497	ARID1A	P24941	CDK2	S1320	P1325L	1325	Missense	distal	5	no	15.061	15.101	EPSD	COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	O14497	ARID1A	P24941	CDK2	S1320	P1326L	1326	Missense	distal	6	no	15.061	15.063	EPSD	COSMIC;CCLE	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	O14497	ARID1A	P24941	CDK2	S1320	R1323C	1323	Missense	distal	3	no	15.061	8.697	EPSD	COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	O14497	ARID1A	P24941	CDK2	S1320	P1325S	1325	Missense	distal	5	no	15.061	14.960	EPSD	COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	O14497	ARID1A	P24941	CDK2	S1320	R1323H	1323	Missense	distal	3	no	15.061	14.365	EPSD	COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	O14497	ARID1A	P24941	CDK2	S1320	D1315G	1315	Missense	distal	-5	no	15.061	15.083	EPSD	COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	O14497	ARID1A	P24941	CDK2	T1348	P1349L	1349	Missense	proximal	1	no	15.419	5.598	EPSD	COSMIC	8.148	Loss
CMGC_CDK_CDK2_CDK2_ST	O14497	ARID1A	P24941	CDK2	T1348	P1355L	1355	Missense	distal	7	no	15.419	15.449	EPSD	COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	O14497	ARID1A	P24941	CDK2	T1348	N1341K	1341	Missense	distal	-7	no	15.419	15.453	EPSD	COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	O14497	ARID1A	P24941	CDK2	T1348	P1355R	1355	Missense	distal	7	no	15.419	15.909	EPSD	COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	O14497	ARID1A	P24941	CDK2	T1348	P1355S	1355	Missense	distal	7	no	15.419	15.267	EPSD	COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	O14497	ARID1A	P24941	CDK2	S1352	P1349L	1349	Missense	distal	-3	no	14.485	14.414	EPSD	COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	O14497	ARID1A	P24941	CDK2	S1352	P1355L	1355	Missense	distal	3	no	14.485	14.102	EPSD	COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	O14497	ARID1A	P24941	CDK2	S1352	S1356I	1356	Missense	distal	4	no	14.485	14.443	EPSD	COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	O14497	ARID1A	P24941	CDK2	S1352	T1359M	1359	Missense	distal	7	no	14.485	15.334	EPSD	COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	O14497	ARID1A	P24941	CDK2	S1352	Q1357H	1357	Missense	distal	5	no	14.485	14.603	EPSD	COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	O14497	ARID1A	P24941	CDK2	S1352	P1355R	1355	Missense	distal	3	no	14.485	16.204	EPSD	COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	O14497	ARID1A	P24941	CDK2	S1352	P1355S	1355	Missense	distal	3	no	14.485	14.519	EPSD	COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	O14497	ARID1A	P24941	CDK2	S1352	Q1358H	1358	Missense	distal	6	no	14.485	14.474	EPSD	COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	O14497	ARID1A	P24941	CDK2	S1587	S1586F	1586	Missense	proximal	-1	no	12.253	13.509	EPSD	COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	O14497	ARID1A	P24941	CDK2	S1587	H1581L	1581	Missense	distal	-6	no	12.253	12.249	EPSD	COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	O14497	ARID1A	P24941	CDK2	S1587	Q1584R	1584	Missense	distal	-3	no	12.253	12.383	EPSD	COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	O14497	ARID1A	P24941	CDK2	S1587	H1581R	1581	Missense	distal	-6	no	12.253	12.251	EPSD	COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	O14497	ARID1A	P24941	CDK2	S1587	P1590L	1590	Missense	distal	3	no	12.253	11.869	EPSD	COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	O14497	ARID1A	P24941	CDK2	S1587	Q1584L	1584	Missense	distal	-3	no	12.253	12.124	EPSD	COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	O14497	ARID1A	P24941	CDK2	S1587	P1592S	1592	Missense	distal	5	no	12.253	12.152	EPSD	COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	O14497	ARID1A	P24941	CDK2	S1587	R1593W	1593	Missense	distal	6	no	12.253	12.245	EPSD	COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	O14497	ARID1A	P24941	CDK2	S1587	P1594L	1594	Missense	distal	7	no	12.253	12.283	EPSD	COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	O14497	ARID1A	P24941	CDK2	S1587	A1589V	1589	Missense	proximal	2	no	12.253	12.351	EPSD	COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	O14497	ARID1A	P24941	CDK2	S1600	S1602P	1602	Missense	proximal	2	no	16.177	16.110	EPSD	COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	O14497	ARID1A	P24941	CDK2	S1600	P1601S	1601	Missense	proximal	1	no	16.177	4.911	EPSD	COSMIC	8.148	Loss
CMGC_CDK_CDK2_CDK2_ST	O14497	ARID1A	P24941	CDK2	S1600	R1598C	1598	Missense	proximal	-2	no	16.177	16.351	EPSD	COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	O14497	ARID1A	P24941	CDK2	S1600	P1605A	1605	Missense	distal	5	no	16.177	16.187	EPSD	COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	O14497	ARID1A	P24941	CDK2	S1600	M1595V	1595	Missense	distal	-5	no	16.177	16.101	EPSD	COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	O14497	ARID1A	P24941	CDK2	S1600	K1603E	1603	Missense	distal	3	no	16.177	14.091	EPSD	COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	O14497	ARID1A	P24941	CDK2	S1600	S1604Y	1604	Missense	distal	4	no	16.177	16.363	EPSD	COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	O14497	ARID1A	P24941	CDK2	S1600	R1593W	1593	Missense	distal	-7	no	16.177	16.347	EPSD	COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	O14497	ARID1A	P24941	CDK2	S1600	T1599I	1599	Missense	proximal	-1	no	16.177	16.423	EPSD	COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	O14497	ARID1A	P24941	CDK2	S1600	P1601L	1601	Missense	proximal	1	no	16.177	6.356	EPSD	COSMIC	8.148	Loss
CMGC_CDK_CDK2_CDK2_ST	O14497	ARID1A	P24941	CDK2	S1604	S1602P	1602	Missense	proximal	-2	no	11.803	12.455	EPSD	COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	O14497	ARID1A	P24941	CDK2	S1604	S1609L	1609	Missense	distal	5	no	11.803	11.944	EPSD	COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	O14497	ARID1A	P24941	CDK2	S1604	P1601S	1601	Missense	distal	-3	no	11.803	11.899	EPSD	COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	O14497	ARID1A	P24941	CDK2	S1604	S1609P	1609	Missense	distal	5	no	11.803	11.904	EPSD	COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	O14497	ARID1A	P24941	CDK2	S1604	G1610E	1610	Missense	distal	6	no	11.803	11.812	EPSD	COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	O14497	ARID1A	P24941	CDK2	S1604	R1598C	1598	Missense	distal	-6	no	11.803	11.806	EPSD	COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	O14497	ARID1A	P24941	CDK2	S1604	P1605A	1605	Missense	proximal	1	no	11.803	-2.600	EPSD	COSMIC	8.148	Loss
CMGC_CDK_CDK2_CDK2_ST	O14497	ARID1A	P24941	CDK2	S1604	K1603E	1603	Missense	proximal	-1	no	11.803	12.688	EPSD	COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	O14497	ARID1A	P24941	CDK2	S1604	S1604Y	1604	Missense	central	0	yes	11.803	0.000	EPSD	COSMIC	8.148	Loss
CMGC_CDK_CDK2_CDK2_ST	O14497	ARID1A	P24941	CDK2	S1604	M1611I	1611	Missense	distal	7	no	11.803	11.315	EPSD	COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	O14497	ARID1A	P24941	CDK2	S1604	T1599I	1599	Missense	distal	-5	no	11.803	11.844	EPSD	COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	O14497	ARID1A	P24941	CDK2	S1604	H1608R	1608	Missense	distal	4	no	11.803	11.921	EPSD	COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	O14497	ARID1A	P24941	CDK2	S1604	P1601L	1601	Missense	distal	-3	no	11.803	11.732	EPSD	COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	O14497	ARID1A	P24941	CDK2	S1609	S1602P	1602	Missense	distal	-7	no	10.801	10.981	EPSD	COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	O14497	ARID1A	P24941	CDK2	S1609	S1609L	1609	Missense	central	0	yes	10.801	0.000	EPSD	COSMIC	8.148	Loss
CMGC_CDK_CDK2_CDK2_ST	O14497	ARID1A	P24941	CDK2	S1609	S1609P	1609	Missense	central	0	yes	10.801	0.000	EPSD	COSMIC	8.148	Loss
CMGC_CDK_CDK2_CDK2_ST	O14497	ARID1A	P24941	CDK2	S1609	G1610E	1610	Missense	proximal	1	no	10.801	8.947	EPSD	COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	O14497	ARID1A	P24941	CDK2	S1609	M1613I	1613	Missense	distal	4	no	10.801	11.193	EPSD	COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	O14497	ARID1A	P24941	CDK2	S1609	P1605A	1605	Missense	distal	-4	no	10.801	10.742	EPSD	COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	O14497	ARID1A	P24941	CDK2	S1609	A1616V	1616	Missense	distal	7	no	10.801	10.674	EPSD	COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	O14497	ARID1A	P24941	CDK2	S1609	K1603E	1603	Missense	distal	-6	no	10.801	10.803	EPSD	COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	O14497	ARID1A	P24941	CDK2	S1609	S1604Y	1604	Missense	distal	-5	no	10.801	10.869	EPSD	COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	O14497	ARID1A	P24941	CDK2	S1609	M1611I	1611	Missense	proximal	2	no	10.801	10.567	EPSD	COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	O14497	ARID1A	P24941	CDK2	S1609	H1608R	1608	Missense	proximal	-1	no	10.801	11.252	EPSD	COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	O14497	ARID1A	P24941	CDK2	T1666	T1666I	1666	Missense	central	0	yes	14.957	0.000	EPSD	COSMIC	8.148	Loss
CMGC_CDK_CDK2_CDK2_ST	O14497	ARID1A	P24941	CDK2	T1666	E1668D	1668	Missense	proximal	2	no	14.957	14.858	EPSD	COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	O14497	ARID1A	P24941	CDK2	T1666	V1672G	1672	Missense	distal	6	no	14.957	14.948	EPSD	COSMIC;GDSC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	O14497	ARID1A	P24941	CDK2	T1666	P1667L	1667	Missense	proximal	1	no	14.957	5.136	EPSD	COSMIC	8.148	Loss
CMGC_CDK_CDK2_CDK2_ST	O14497	ARID1A	P24941	CDK2	T1666	I1664F	1664	Missense	proximal	-2	no	14.957	13.998	EPSD	COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	O14497	ARID1A	P24941	CDK2	T1666	P1667S	1667	Missense	proximal	1	no	14.957	3.691	EPSD	COSMIC	8.148	Loss
CMGC_CDK_CDK2_CDK2_ST	O14497	ARID1A	P24941	CDK2	T1666	R1671W	1671	Missense	distal	5	no	14.957	15.124	EPSD	COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	O14497	ARID1A	P24941	CDK2	T1666	D1663H	1663	Missense	distal	-3	no	14.957	15.038	EPSD	COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	O14497	ARID1A	P24941	CDK2	S1755	P1756H	1756	Missense	proximal	1	no	14.401	7.642	EPSD	COSMIC	8.148	Loss
CMGC_CDK_CDK2_CDK2_ST	O14497	ARID1A	P24941	CDK2	S1755	P1756L	1756	Missense	proximal	1	no	14.401	4.580	EPSD	COSMIC	8.148	Loss
CMGC_CDK_CDK2_CDK2_ST	O14497	ARID1A	P24941	CDK2	S1755	S1751N	1751	Missense	distal	-4	no	14.401	14.185	EPSD	COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	O14497	ARID1A	P24941	CDK2	S1755	M1759V	1759	Missense	distal	4	no	14.401	15.049	EPSD	COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	O14497	ARID1A	P24941	CDK2	T1888	T1888P	1888	Missense	central	0	yes	14.012	0.000	EPSD	COSMIC	8.148	Loss
CMGC_CDK_CDK2_CDK2_ST	O14497	ARID1A	P24941	CDK2	T1888	T1888I	1888	Missense	central	0	yes	14.012	0.000	EPSD	COSMIC	8.148	Loss
CMGC_CDK_CDK2_CDK2_ST	O14497	ARID1A	P24941	CDK2	T1888	G1890C	1890	Missense	proximal	2	no	14.012	14.041	EPSD	COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	O14497	ARID1A	P24941	CDK2	T1888	T1892I	1892	Missense	distal	4	no	14.012	13.701	EPSD	COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	O14497	ARID1A	P24941	CDK2	T1888	T1883I	1883	Missense	distal	-5	no	14.012	14.053	EPSD	COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	O14497	ARID1A	P24941	CDK2	T1888	G1887D	1887	Missense	proximal	-1	no	14.012	13.719	EPSD	COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	O14497	ARID1A	P24941	CDK2	T1888	V1882M	1882	Missense	distal	-6	no	14.012	14.018	EPSD	COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	O14497	ARID1A	P24941	CDK2	T1888	A1885S	1885	Missense	distal	-3	no	14.012	14.166	EPSD	COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	O14497	ARID1A	P24941	CDK2	T1888	G1890V	1890	Missense	proximal	2	no	14.012	14.017	EPSD	COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	O14497	ARID1A	P24941	CDK2	T1888	T1884S	1884	Missense	distal	-4	no	14.012	14.200	EPSD	COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	O14497	ARID1A	P24941	CDK2	S1920	T1921P	1921	Missense	proximal	1	no	3.400	13.357	EPSD	COSMIC	8.148	Gain
CMGC_CDK_CDK2_CDK2_ST	O14497	ARID1A	P24941	CDK2	S1944	R1950Q	1950	Missense	distal	6	no	14.606	14.628	EPSD	COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	O14497	ARID1A	P24941	CDK2	S1944	G1942D	1942	Missense	proximal	-2	no	14.606	15.214	EPSD	COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	O14497	ARID1A	P24941	CDK2	S1944	P1940S	1940	Missense	distal	-4	no	14.606	14.961	EPSD	COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	O14497	ARID1A	P24941	CDK2	S1944	R1950W	1950	Missense	distal	6	no	14.606	14.599	EPSD	COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	O14497	ARID1A	P24941	CDK2	S1944	P1940L	1940	Missense	distal	-4	no	14.606	14.548	EPSD	COSMIC;GDSC;CCLE	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	O14497	ARID1A	P24941	CDK2	S1948	K1953N	1953	Missense	distal	5	no	8.153	8.310	EPSD	COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	O14497	ARID1A	P24941	CDK2	S1948	R1950Q	1950	Missense	proximal	2	no	8.153	8.053	EPSD	COSMIC	8.148	Loss
CMGC_CDK_CDK2_CDK2_ST	O14497	ARID1A	P24941	CDK2	S1948	G1942D	1942	Missense	distal	-6	no	8.153	8.149	EPSD	COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	O14497	ARID1A	P24941	CDK2	S1948	R1950W	1950	Missense	proximal	2	no	8.153	8.250	EPSD	COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	O14497	ARID1A	P24941	CDK2	S1948	K1953R	1953	Missense	distal	5	no	8.153	8.314	EPSD	COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	O14497	ARID1A	P24941	CDK2	S2113	V2111I	2111	Missense	proximal	-2	no	13.433	13.929	EPSD	COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	O14497	ARID1A	P24941	CDK2	S2113	L2106M	2106	Missense	distal	-7	no	13.433	13.929	EPSD	COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	O14497	ARID1A	P24941	CDK2	S2113	S2113F	2113	Missense	central	0	yes	13.433	0.000	EPSD	COSMIC	8.148	Loss
CMGC_CDK_CDK2_CDK2_ST	O14497	ARID1A	P24941	CDK2	S2113	G2107C	2107	Missense	distal	-6	no	13.433	13.436	EPSD	COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	O14497	ARID1A	P24941	CDK2	S2113	V2118I	2118	Missense	distal	5	no	13.433	13.559	EPSD	COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	Q15910	EZH2	P24941	CDK2	S212	R213H	213	Missense	proximal	1	no	5.282	8.322	EPSD	COSMIC	8.148	Gain
CMGC_CDK_CDK2_CDK2_ST	Q15910	EZH2	P24941	CDK2	T261	I264T	264	Missense	distal	3	no	12.636	13.189	EPSD	COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	Q15910	EZH2	P24941	CDK2	T261	P262H	262	Missense	proximal	1	no	12.636	5.877	EPSD	COSMIC	8.148	Loss
CMGC_CDK_CDK2_CDK2_ST	Q15910	EZH2	P24941	CDK2	T261	G254A	254	Missense	distal	-7	no	12.636	12.476	EPSD	COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	Q15910	EZH2	P24941	CDK2	T261	T261A	261	Missense	central	0	yes	12.636	0.000	EPSD	COSMIC	8.148	Loss
CMGC_CDK_CDK2_CDK2_ST	Q15910	EZH2	P24941	CDK2	T261	A255T	255	Missense	distal	-6	no	12.636	12.637	EPSD	COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	Q15910	EZH2	P24941	CDK2	T261	P262L	262	Missense	proximal	1	no	12.636	2.815	EPSD	COSMIC	8.148	Loss
CMGC_CDK_CDK2_CDK2_ST	Q15910	EZH2	P24941	CDK2	T261	P262T	262	Missense	proximal	1	no	12.636	2.678	EPSD	COSMIC	8.148	Loss
CMGC_CDK_CDK2_CDK2_ST	Q15910	EZH2	P24941	CDK2	T261	I264R	264	Missense	distal	3	no	12.636	15.022	EPSD	COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	Q15910	EZH2	P24941	CDK2	T261	G266E	266	Missense	distal	5	no	12.636	12.588	EPSD	COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	Q15910	EZH2	P24941	CDK2	T261	G266R	266	Missense	distal	5	no	12.636	12.615	EPSD	COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	Q15910	EZH2	P24941	CDK2	T261	T261N	261	Missense	central	0	yes	12.636	0.000	EPSD	COSMIC	8.148	Loss
CMGC_CDK_CDK2_CDK2_ST	Q15910	EZH2	P24941	CDK2	T302	R308Q	308	Missense	distal	6	no	11.042	11.064	EPSD	COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	Q15910	EZH2	P24941	CDK2	T302	N304S	304	Missense	proximal	2	no	11.042	11.179	EPSD	COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	Q15910	EZH2	P24941	CDK2	T302	R308L	308	Missense	distal	6	no	11.042	11.060	EPSD	COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	Q15910	EZH2	P24941	CDK2	T302	P298S	298	Missense	distal	-4	no	11.042	11.397	EPSD	COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	Q15910	EZH2	P24941	CDK2	T302	R308W	308	Missense	distal	6	no	11.042	11.035	EPSD	COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	Q15910	EZH2	P24941	CDK2	T302	H300Y	300	Missense	proximal	-2	no	11.042	11.488	EPSD	COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	Q15910	EZH2	P24941	CDK2	T302	H300R	300	Missense	proximal	-2	no	11.042	10.816	EPSD	COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	Q15910	EZH2	P24941	CDK2	T302	A301T	301	Missense	proximal	-1	no	11.042	11.049	EPSD	COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	Q15910	EZH2	P24941	CDK2	T345	R342W	342	Missense	distal	-3	no	16.708	16.789	EPSD;PhosphoSitePlus	COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	Q15910	EZH2	P24941	CDK2	T345	R349C	349	Missense	distal	4	no	16.708	16.081	EPSD;PhosphoSitePlus	COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	Q15910	EZH2	P24941	CDK2	T345	R342Q	342	Missense	distal	-3	no	16.708	16.577	EPSD;PhosphoSitePlus	COSMIC;CCLE	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	Q15910	EZH2	P24941	CDK2	T345	R342L	342	Missense	distal	-3	no	16.708	16.448	EPSD;PhosphoSitePlus	COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	Q15910	EZH2	P24941	CDK2	T345	A340T	340	Missense	distal	-5	no	16.708	16.682	EPSD;PhosphoSitePlus	COSMIC;CCLE	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	Q15910	EZH2	P24941	CDK2	T345	E341K	341	Missense	distal	-4	no	16.708	16.396	EPSD;PhosphoSitePlus	COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	Q15910	EZH2	P24941	CDK2	T345	L338F	338	Missense	distal	-7	no	16.708	17.074	EPSD;PhosphoSitePlus	COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	Q15910	EZH2	P24941	CDK2	T367	S363N	363	Missense	distal	-4	no	11.019	10.803	EPSD	COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	Q15910	EZH2	P24941	CDK2	T367	P368S	368	Missense	proximal	1	no	11.019	-0.247	EPSD	COSMIC	8.148	Loss
CMGC_CDK_CDK2_CDK2_ST	Q15910	EZH2	P24941	CDK2	T367	E374Q	374	Missense	distal	7	no	11.019	10.820	EPSD	COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	Q15910	EZH2	P24941	CDK2	T367	L373V	373	Missense	distal	6	no	11.019	11.016	EPSD	COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	Q15910	EZH2	P24941	CDK2	T367	S363C	363	Missense	distal	-4	no	11.019	9.913	EPSD	COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	Q15910	EZH2	P24941	CDK2	T367	S366L	366	Missense	proximal	-1	no	11.019	11.310	EPSD	COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	Q15910	EZH2	P24941	CDK2	T388	E391K	391	Missense	distal	3	no	8.402	10.488	EPSD	COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	Q15910	EZH2	P24941	CDK2	T388	R382M	382	Missense	distal	-6	no	8.402	8.408	EPSD	COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	Q15910	EZH2	P24941	CDK2	T388	E391D	391	Missense	distal	3	no	8.402	5.967	EPSD	COSMIC	8.148	Loss
CMGC_CDK_CDK2_CDK2_ST	Q15910	EZH2	P24941	CDK2	T388	R382W	382	Missense	distal	-6	no	8.402	8.408	EPSD	COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	Q15910	EZH2	P24941	CDK2	T388	K395T	395	Missense	distal	7	no	8.402	8.385	EPSD	COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	Q15910	EZH2	P24941	CDK2	T416	P422L	422	Missense	distal	6	no	16.244	16.245	PhosphoSitePlus;EPSD	COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	Q15910	EZH2	P24941	CDK2	T416	P422Q	422	Missense	distal	6	no	16.244	16.250	PhosphoSitePlus;EPSD	COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	Q15910	EZH2	P24941	CDK2	T416	R413W	413	Missense	distal	-3	no	16.244	16.325	PhosphoSitePlus;EPSD	COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	Q15910	EZH2	P24941	CDK2	T416	P417L	417	Missense	proximal	1	no	16.244	6.423	PhosphoSitePlus;EPSD	COSMIC	8.148	Loss
CMGC_CDK_CDK2_CDK2_ST	Q15910	EZH2	P24941	CDK2	T416	E409K	409	Missense	distal	-7	no	16.244	16.106	PhosphoSitePlus;EPSD	COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	Q15910	EZH2	P24941	CDK2	T416	S412F	412	Missense	distal	-4	no	16.244	15.282	PhosphoSitePlus;EPSD	COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	Q15910	EZH2	P24941	CDK2	T416	N423T	423	Missense	distal	7	no	16.244	16.033	PhosphoSitePlus;EPSD	COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	Q15910	EZH2	P24941	CDK2	T416	Q415E	415	Missense	proximal	-1	no	16.244	17.336	PhosphoSitePlus;EPSD	COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	Q15910	EZH2	P24941	CDK2	T416	P417Q	417	Missense	proximal	1	no	16.244	8.332	PhosphoSitePlus;EPSD	COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	Q15910	EZH2	P24941	CDK2	T416	R413Q	413	Missense	distal	-3	no	16.244	16.113	PhosphoSitePlus;EPSD	COSMIC;CCLE	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	Q15910	EZH2	P24941	CDK2	T487	A482T	482	Missense	distal	-5	no	16.503	16.477	EPSD	COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	Q15910	EZH2	P24941	CDK2	T487	P488S	488	Missense	proximal	1	no	16.503	5.238	EPSD	COSMIC	8.148	Loss
CMGC_CDK_CDK2_CDK2_ST	Q15910	EZH2	P24941	CDK2	T487	R494S	494	Missense	distal	7	no	16.503	15.862	EPSD	COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	Q15910	EZH2	P24941	CDK2	T487	R494K	494	Missense	distal	7	no	16.503	15.727	EPSD	COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	Q15910	EZH2	P24941	CDK2	T487	P481S	481	Missense	distal	-6	no	16.503	16.502	EPSD	COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	Q15910	EZH2	P24941	CDK2	T487	P488A	488	Missense	proximal	1	no	16.503	2.100	EPSD	COSMIC	8.148	Loss
CMGC_CDK_CDK2_CDK2_ST	Q15910	EZH2	P24941	CDK2	T487	K491R	491	Missense	distal	4	no	16.503	15.982	EPSD	COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	Q96T88	UHRF1	P24941	CDK2	S104	G100R	100	Missense	distal	-4	no	9.148	9.223	EPSD	COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	Q96T88	UHRF1	P24941	CDK2	S104	G111S	111	Missense	distal	7	no	9.148	8.326	EPSD	COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	Q96T88	UHRF1	P24941	CDK2	S104	G111D	111	Missense	distal	7	no	9.148	9.164	EPSD	COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	Q96T88	UHRF1	P24941	CDK2	S104	D105Y	105	Missense	proximal	1	no	9.148	1.893	EPSD	COSMIC	8.148	Loss
CMGC_CDK_CDK2_CDK2_ST	Q96T88	UHRF1	P24941	CDK2	S104	D105N	105	Missense	proximal	1	no	9.148	-23.221	EPSD	COSMIC	8.148	Loss
CMGC_CDK_CDK2_CDK2_ST	Q96T88	UHRF1	P24941	CDK2	S104	E103K	103	Missense	proximal	-1	no	9.148	8.263	EPSD	COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	Q96T88	UHRF1	P24941	CDK2	S104	L99P	99	Missense	distal	-5	no	9.148	9.136	EPSD	COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	Q96T88	UHRF1	P24941	CDK2	T117	E116K	116	Missense	proximal	-1	no	10.330	9.445	EPSD	COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	Q96T88	UHRF1	P24941	CDK2	T117	A115T	115	Missense	proximal	-2	no	10.330	10.281	EPSD	COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	Q96T88	UHRF1	P24941	CDK2	T117	A115V	115	Missense	proximal	-2	no	10.330	9.664	EPSD	COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	Q96T88	UHRF1	P24941	CDK2	T117	G111S	111	Missense	distal	-6	no	10.330	10.327	EPSD	COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	Q96T88	UHRF1	P24941	CDK2	T117	D123N	123	Missense	distal	6	no	10.330	10.349	EPSD	COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	Q96T88	UHRF1	P24941	CDK2	T117	G111D	111	Missense	distal	-6	no	10.330	10.326	EPSD	COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	Q96T88	UHRF1	P24941	CDK2	T117	S119N	119	Missense	proximal	2	no	10.330	10.193	EPSD	COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	Q96T88	UHRF1	P24941	CDK2	T117	A114S	114	Missense	distal	-3	no	10.330	10.484	EPSD	COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	Q96T88	UHRF1	P24941	CDK2	S287	P288L	288	Missense	proximal	1	no	15.790	5.969	EPSD	COSMIC	8.148	Loss
CMGC_CDK_CDK2_CDK2_ST	Q96T88	UHRF1	P24941	CDK2	S287	P288S	288	Missense	proximal	1	no	15.790	4.524	EPSD	COSMIC	8.148	Loss
CMGC_CDK_CDK2_CDK2_ST	Q96T88	UHRF1	P24941	CDK2	S287	R282Q	282	Missense	distal	-5	no	15.790	15.743	EPSD	COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	Q96T88	UHRF1	P24941	CDK2	S287	P293L	293	Missense	distal	6	no	15.790	15.791	EPSD	COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	Q96T88	UHRF1	P24941	CDK2	S298	R295I	295	Missense	distal	-3	no	8.233	8.064	EPSD	COSMIC	8.148	Loss
CMGC_CDK_CDK2_CDK2_ST	Q96T88	UHRF1	P24941	CDK2	S298	P293L	293	Missense	distal	-5	no	8.233	8.245	EPSD	COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	Q96T88	UHRF1	P24941	CDK2	S298	G299R	299	Missense	proximal	1	no	8.233	5.747	EPSD	COSMIC	8.148	Loss
CMGC_CDK_CDK2_CDK2_ST	Q96T88	UHRF1	P24941	CDK2	S298	R295Q	295	Missense	distal	-3	no	8.233	8.102	EPSD	COSMIC	8.148	Loss
CMGC_CDK_CDK2_CDK2_ST	Q96T88	UHRF1	P24941	CDK2	S439	E438K	438	Missense	proximal	-1	no	8.285	7.399	EPSD	COSMIC	8.148	Loss
CMGC_CDK_CDK2_CDK2_ST	Q96T88	UHRF1	P24941	CDK2	S639	G636S	636	Missense	distal	-3	no	13.616	13.608	EPSD	COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	Q96T88	UHRF1	P24941	CDK2	S639	G645C	645	Missense	distal	6	no	13.616	13.614	EPSD	COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	Q96T88	UHRF1	P24941	CDK2	S639	G636V	636	Missense	distal	-3	no	13.616	13.656	EPSD	COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	Q96T88	UHRF1	P24941	CDK2	S639	Q632E	632	Missense	distal	-7	no	13.616	13.749	EPSD	COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	Q96T88	UHRF1	P24941	CDK2	S639	P640T	640	Missense	proximal	1	no	13.616	3.659	EPSD	COSMIC	8.148	Loss
CMGC_CDK_CDK2_CDK2_ST	Q96T88	UHRF1	P24941	CDK2	S639	E634K	634	Missense	distal	-5	no	13.616	13.582	EPSD	COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	Q96T88	UHRF1	P24941	CDK2	S639	R641H	641	Missense	proximal	2	no	13.616	13.535	EPSD	COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	Q96T88	UHRF1	P24941	CDK2	S639	G636E	636	Missense	distal	-3	no	13.616	13.687	EPSD	COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	Q96T88	UHRF1	P24941	CDK2	S639	F637L	637	Missense	proximal	-2	no	13.616	14.505	EPSD	COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	Q96T88	UHRF1	P24941	CDK2	S661	G660R	660	Missense	proximal	-1	no	18.201	17.723	EPSD;PhosphoSitePlus	COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	Q96T88	UHRF1	P24941	CDK2	S661	A659V	659	Missense	proximal	-2	no	18.201	17.535	EPSD;PhosphoSitePlus	COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	Q96T88	UHRF1	P24941	CDK2	S661	P662L	662	Missense	proximal	1	no	18.201	8.380	EPSD;PhosphoSitePlus	COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	Q96T88	UHRF1	P24941	CDK2	S661	P662S	662	Missense	proximal	1	no	18.201	6.935	EPSD;PhosphoSitePlus	COSMIC	8.148	Loss
CMGC_CDK_CDK2_CDK2_ST	Q96T88	UHRF1	P24941	CDK2	S661	S661F	661	Missense	central	0	yes	18.201	0.000	EPSD;PhosphoSitePlus	COSMIC	8.148	Loss
CMGC_CDK_CDK2_CDK2_ST	Q96T88	UHRF1	P24941	CDK2	S661	S666F	666	Missense	distal	5	no	18.201	18.519	EPSD;PhosphoSitePlus	COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	Q96T88	UHRF1	P24941	CDK2	S707	R704W	704	Missense	distal	-3	no	8.556	8.637	EPSD	COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	Q96T88	UHRF1	P24941	CDK2	S707	F714L	714	Missense	distal	7	no	8.556	7.885	EPSD	COSMIC	8.148	Loss
CMGC_CDK_CDK2_CDK2_ST	Q96T88	UHRF1	P24941	CDK2	S707	P710L	710	Missense	distal	3	no	8.556	8.173	EPSD	COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	Q96T88	UHRF1	P24941	CDK2	S707	P705L	705	Missense	proximal	-2	no	8.556	8.332	EPSD	COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	Q96T88	UHRF1	P24941	CDK2	S709	R704W	704	Missense	distal	-5	no	15.347	15.435	EPSD	COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	Q96T88	UHRF1	P24941	CDK2	S709	F714L	714	Missense	distal	5	no	15.347	15.170	EPSD	COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	Q96T88	UHRF1	P24941	CDK2	S709	P710L	710	Missense	proximal	1	no	15.347	5.526	EPSD	COSMIC	8.148	Loss
CMGC_CDK_CDK2_CDK2_ST	Q96T88	UHRF1	P24941	CDK2	S709	P705L	705	Missense	distal	-4	no	15.347	15.289	EPSD	COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	Q9H910	JPT2	P24941	CDK2	S30	S25C	25	Missense	distal	-5	no	14.154	14.279	EPSD	COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	Q9H910	JPT2	P24941	CDK2	S30	S37C	37	Missense	distal	7	no	14.154	14.946	EPSD	COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	Q9H910	JPT2	P24941	CDK2	S30	G29E	29	Missense	proximal	-1	no	14.154	13.890	EPSD	COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	Q9H910	JPT2	P24941	CDK2	S30	P36S	36	Missense	distal	6	no	14.154	14.155	EPSD	COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	Q9H910	JPT2	P24941	CDK2	S30	L27R	27	Missense	distal	-3	no	14.154	14.413	EPSD	COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	Q9H910	JPT2	P24941	CDK2	T35	S37C	37	Missense	proximal	2	no	12.747	12.827	EPSD	COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	Q9H910	JPT2	P24941	CDK2	T35	G29E	29	Missense	distal	-6	no	12.747	12.748	EPSD	COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	Q9H910	JPT2	P24941	CDK2	T35	P36S	36	Missense	proximal	1	no	12.747	1.482	EPSD	COSMIC	8.148	Loss
CMGC_CDK_CDK2_CDK2_ST	Q9H910	JPT2	P24941	CDK2	T76	H83Y	83	Missense	distal	7	no	11.038	11.176	EPSD	COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	Q9H910	JPT2	P24941	CDK2	T76	T76A	76	Missense	central	0	yes	11.038	0.000	EPSD	COSMIC	8.148	Loss
CMGC_CDK_CDK2_CDK2_ST	Q9H910	JPT2	P24941	CDK2	T76	R81Q	81	Missense	distal	5	no	11.038	10.892	EPSD	COSMIC;GDSC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	Q9H910	JPT2	P24941	CDK2	T76	P77S	77	Missense	proximal	1	no	11.038	-0.228	EPSD	COSMIC	8.148	Loss
CMGC_CDK_CDK2_CDK2_ST	Q9H910	JPT2	P24941	CDK2	S97	P98Q	98	Missense	proximal	1	no	14.683	6.772	PhosphoSitePlus	COSMIC	8.148	Loss
CMGC_CDK_CDK2_CDK2_ST	Q9H910	JPT2	P24941	CDK2	S97	R104H	104	Missense	distal	7	no	14.683	14.325	PhosphoSitePlus	COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	Q9H910	JPT2	P24941	CDK2	S97	D93N	93	Missense	distal	-4	no	14.683	14.295	PhosphoSitePlus	COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	Q9H910	JPT2	P24941	CDK2	S125	G120V	120	Missense	distal	-5	no	8.954	8.905	EPSD	COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	Q9H910	JPT2	P24941	CDK2	S125	C118R	118	Missense	distal	-7	no	8.954	9.026	EPSD	COSMIC;GDSC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	Q9H910	JPT2	P24941	CDK2	S125	S125L	125	Missense	central	0	yes	8.954	0.000	EPSD	COSMIC	8.148	Loss
CMGC_CDK_CDK2_CDK2_ST	Q9H910	JPT2	P24941	CDK2	S125	K124R	124	Missense	proximal	-1	no	8.954	9.624	EPSD	COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	Q9H910	JPT2	P24941	CDK2	S125	R131S	131	Missense	distal	6	no	8.954	8.971	EPSD	COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	Q9H910	JPT2	P24941	CDK2	S125	E122K	122	Missense	distal	-3	no	8.954	8.738	EPSD	COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	Q9H910	JPT2	P24941	CDK2	S173	G168R	168	Missense	distal	-5	no	10.919	10.887	EPSD	COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	Q9H910	JPT2	P24941	CDK2	S173	L178P	178	Missense	distal	5	no	10.919	10.879	EPSD	COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	Q9H910	JPT2	P24941	CDK2	S173	R172C	172	Missense	proximal	-1	no	10.919	10.222	EPSD	COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	Q9H910	JPT2	P24941	CDK2	S173	P169L	169	Missense	distal	-4	no	10.919	10.861	EPSD	COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	Q9H910	JPT2	P24941	CDK2	S173	R170G	170	Missense	distal	-3	no	10.919	10.834	EPSD	COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	Q9H910	JPT2	P24941	CDK2	S173	R172P	172	Missense	proximal	-1	no	10.919	10.349	EPSD	COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	Q9H910	JPT2	P24941	CDK2	S173	P169S	169	Missense	distal	-4	no	10.919	11.274	EPSD	COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	Q9H910	JPT2	P24941	CDK2	S173	R170W	170	Missense	distal	-3	no	10.919	11.000	EPSD	COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	Q9H910	JPT2	P24941	CDK2	S173	R166W	166	Missense	distal	-7	no	10.919	11.090	EPSD	COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	Q9H910	JPT2	P24941	CDK2	S173	K176N	176	Missense	distal	3	no	10.919	7.649	EPSD	COSMIC	8.148	Loss
CMGC_CDK_CDK2_CDK2_ST	Q7KZ85	SUPT6H	P24941	CDK2	T327	E334K	334	Missense	distal	7	no	14.344	14.014	EPSD	COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	Q7KZ85	SUPT6H	P24941	CDK2	T327	S331Y	331	Missense	distal	4	no	14.344	14.530	EPSD	COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	Q7KZ85	SUPT6H	P24941	CDK2	T619	E612D	612	Missense	distal	-7	no	12.869	13.020	EPSD	COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	Q7KZ85	SUPT6H	P24941	CDK2	T1523	Q1516K	1516	Missense	distal	-7	no	11.752	11.748	PhosphoSitePlus	COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	Q7KZ85	SUPT6H	P24941	CDK2	T1532	I1536S	1536	Missense	distal	4	no	13.927	13.969	EPSD	COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	Q7KZ85	SUPT6H	P24941	CDK2	T1539	I1536S	1536	Missense	distal	-3	no	12.370	12.446	EPSD	COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	Q7KZ85	SUPT6H	P24941	CDK2	T1539	P1540L	1540	Missense	proximal	1	no	12.370	2.550	EPSD	COSMIC	8.148	Loss
CMGC_CDK_CDK2_CDK2_ST	Q7KZ85	SUPT6H	P24941	CDK2	T1539	N1542S	1542	Missense	distal	3	no	12.370	12.967	EPSD	COSMIC;CCLE	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	Q7KZ85	SUPT6H	P24941	CDK2	T1580	P1577S	1577	Missense	distal	-3	no	12.153	12.249	EPSD	COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	Q7KZ85	SUPT6H	P24941	CDK2	T1614	P1619L	1619	Missense	distal	5	no	11.362	11.401	EPSD	COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	Q7KZ85	SUPT6H	P24941	CDK2	T1618	P1619L	1619	Missense	proximal	1	no	12.531	2.711	EPSD	COSMIC	8.148	Loss
CMGC_CDK_CDK2_CDK2_ST	Q7KZ85	SUPT6H	P24941	CDK2	S1668	A1670V	1670	Missense	proximal	2	no	8.551	8.649	EPSD	COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	Q7KZ85	SUPT6H	P24941	CDK2	T1697	S1701F	1701	Missense	distal	4	no	12.430	12.234	EPSD	COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	Q7KZ85	SUPT6H	P24941	CDK2	S1701	M1705L	1705	Missense	distal	4	no	14.762	15.295	EPSD	COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	Q7KZ85	SUPT6H	P24941	CDK2	S1701	S1701F	1701	Missense	central	0	yes	14.762	0.000	EPSD	COSMIC	8.148	Loss
CMGC_CDK_CDK2_CDK2_ST	Q7KZ85	SUPT6H	P24941	CDK2	S1703	M1705L	1705	Missense	proximal	2	no	12.593	12.275	EPSD	COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	Q7KZ85	SUPT6H	P24941	CDK2	S1703	S1701F	1701	Missense	proximal	-2	no	12.593	12.131	EPSD	COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	Q7KZ85	SUPT6H	P24941	CDK2	T1709	M1705L	1705	Missense	distal	-4	no	14.085	14.775	EPSD	COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	Q7KZ85	SUPT6H	P24941	CDK2	T1718	L1721P	1721	Missense	distal	3	no	13.489	13.872	EPSD	COSMIC;GDSC;CCLE	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	Q7KZ85	SUPT6H	P24941	CDK2	T1718	P1719L	1719	Missense	proximal	1	no	13.489	3.668	EPSD	COSMIC	8.148	Loss
CMGC_CDK_CDK2_CDK2_ST	Q12948	FOXC1	P24941	CDK2	T68	P73H	73	Missense	distal	5	no	16.913	16.991	PhosphoSitePlus	COSMIC;GDSC;CCLE	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	Q12948	FOXC1	P24941	CDK2	S235	P242L	242	Missense	distal	7	no	9.052	9.083	EPSD	COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	Q12948	FOXC1	P24941	CDK2	S235	E229D	229	Missense	distal	-6	no	9.052	9.048	EPSD	COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	Q12948	FOXC1	P24941	CDK2	S241	P242L	242	Missense	proximal	1	no	12.910	3.089	EPSD	COSMIC	8.148	Loss
CMGC_CDK_CDK2_CDK2_ST	Q12948	FOXC1	P24941	CDK2	S259	I257M	257	Missense	proximal	-2	no	13.897	11.966	EPSD	COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	Q12948	FOXC1	P24941	CDK2	S259	P260L	260	Missense	proximal	1	no	13.897	4.076	EPSD	COSMIC	8.148	Loss
CMGC_CDK_CDK2_CDK2_ST	Q12948	FOXC1	P24941	CDK2	S320	A325D	325	Missense	distal	5	no	12.361	12.525	EPSD	COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	Q12948	FOXC1	P24941	CDK2	S521	R515K	515	Missense	distal	-6	no	8.496	8.494	EPSD	COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	Q6UB35	MTHFD1L	P24941	CDK2	S357	L351S	351	Missense	distal	-6	no	14.360	14.359	PhosphoSitePlus	COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	Q6UB35	MTHFD1L	P24941	CDK2	T421	L416S	416	Missense	distal	-5	no	11.399	11.343	EPSD	COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	Q6UB35	MTHFD1L	P24941	CDK2	T423	L416S	416	Missense	distal	-7	no	11.488	11.302	EPSD	COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	Q6UB35	MTHFD1L	P24941	CDK2	S932	A936V	936	Missense	distal	4	no	7.972	8.159	EPSD	COSMIC	8.148	Gain
CMGC_CDK_CDK2_CDK2_ST	Q15047	SETDB1	P24941	CDK2	T144	P145L	145	Missense	proximal	1	no	11.022	1.201	EPSD	COSMIC	8.148	Loss
CMGC_CDK_CDK2_CDK2_ST	Q15047	SETDB1	P24941	CDK2	T443	T441S	441	Missense	proximal	-2	no	9.880	9.262	EPSD	COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	Q15047	SETDB1	P24941	CDK2	T443	T439A	439	Missense	distal	-4	no	9.880	9.655	EPSD	COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	Q15047	SETDB1	P24941	CDK2	S505	G502A	502	Missense	distal	-3	no	12.742	12.580	EPSD	COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	Q15047	SETDB1	P24941	CDK2	S508	G502A	502	Missense	distal	-6	no	13.979	13.975	EPSD	COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	Q15047	SETDB1	P24941	CDK2	S528	T525I	525	Missense	distal	-3	no	12.702	12.761	EPSD	COSMIC;GDSC;CCLE	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	Q15047	SETDB1	P24941	CDK2	S528	I522V	522	Missense	distal	-6	no	12.702	12.701	EPSD	COSMIC;GDSC;CCLE	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	Q15047	SETDB1	P24941	CDK2	S528	P529L	529	Missense	proximal	1	no	12.702	2.881	EPSD	COSMIC	8.148	Loss
CMGC_CDK_CDK2_CDK2_ST	Q15047	SETDB1	P24941	CDK2	T700	C693Y	693	Missense	distal	-7	no	14.090	13.945	EPSD	COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	Q15047	SETDB1	P24941	CDK2	T700	T699K	699	Missense	proximal	-1	no	14.090	14.253	EPSD	COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	Q15047	SETDB1	P24941	CDK2	T700	P701S	701	Missense	proximal	1	no	14.090	2.824	EPSD	COSMIC	8.148	Loss
CMGC_CDK_CDK2_CDK2_ST	Q15047	SETDB1	P24941	CDK2	S905	S906P	906	Missense	proximal	1	no	2.968	14.234	EPSD	COSMIC	8.148	Gain
CMGC_CDK_CDK2_CDK2_ST	Q15047	SETDB1	P24941	CDK2	S906	C911F	911	Missense	distal	5	no	8.602	8.586	EPSD	COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	Q15047	SETDB1	P24941	CDK2	S906	S906P	906	Missense	central	0	yes	8.602	0.000	EPSD	COSMIC	8.148	Loss
CMGC_CDK_CDK2_CDK2_ST	Q15047	SETDB1	P24941	CDK2	S1025	T1026P	1026	Missense	proximal	1	no	3.975	13.932	EPSD	COSMIC	8.148	Gain
CMGC_CDK_CDK2_CDK2_ST	Q15047	SETDB1	P24941	CDK2	S1066	S1066P	1066	Missense	central	0	yes	16.411	0.000	PhosphoSitePlus	COSMIC	8.148	Loss
CMGC_CDK_CDK2_CDK2_ST	Q15047	SETDB1	P24941	CDK2	S1130	S1137F	1137	Missense	distal	7	no	7.661	8.515	EPSD	COSMIC	8.148	Gain
CMGC_CDK_CDK2_CDK2_ST	Q15047	SETDB1	P24941	CDK2	S1130	V1128I	1128	Missense	proximal	-2	no	7.661	8.156	EPSD	COSMIC	8.148	Gain
CMGC_CDK_CDK2_CDK2_ST	Q15047	SETDB1	P24941	CDK2	S1138	S1137F	1137	Missense	proximal	-1	no	7.950	9.207	EPSD	COSMIC	8.148	Gain
CMGC_CDK_CDK2_CDK2_ST	Q15047	SETDB1	P24941	CDK2	S1179	T1180P	1180	Missense	proximal	1	no	2.764	12.721	EPSD	COSMIC	8.148	Gain
CMGC_CDK_CDK2_CDK2_ST	O60934	NBN	P24941	CDK2	T337	L342H	342	Missense	distal	5	no	14.306	14.344	EPSD	COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	O60934	NBN	P24941	CDK2	T337	P338S	338	Missense	proximal	1	no	14.306	3.040	EPSD	COSMIC	8.148	Loss
CMGC_CDK_CDK2_CDK2_ST	O60934	NBN	P24941	CDK2	S432	I439V	439	Missense	distal	7	no	16.721	16.922	PhosphoSitePlus	COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	O60934	NBN	P24941	CDK2	S432	I426M	426	Missense	distal	-6	no	16.721	16.726	PhosphoSitePlus	COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	O60934	NBN	P24941	CDK2	S432	S432P	432	Missense	central	0	yes	16.721	0.000	PhosphoSitePlus	COSMIC	8.148	Loss
CMGC_CDK_CDK2_CDK2_ST	O60934	NBN	P24941	CDK2	S432	Y429H	429	Missense	distal	-3	no	16.721	16.752	PhosphoSitePlus	COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	O60934	NBN	P24941	CDK2	S462	P461L	461	Missense	proximal	-1	no	8.501	8.322	EPSD	COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	O60934	NBN	P24941	CDK2	S462	R466K	466	Missense	distal	4	no	8.501	9.023	EPSD	COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	O60934	NBN	P24941	CDK2	S462	I455V	455	Missense	distal	-7	no	8.501	8.327	EPSD	COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	O60934	NBN	P24941	CDK2	S462	D469N	469	Missense	distal	7	no	8.501	7.721	EPSD	COSMIC	8.148	Loss
CMGC_CDK_CDK2_CDK2_ST	O60934	NBN	P24941	CDK2	S462	R468M	468	Missense	distal	6	no	8.501	8.499	EPSD	COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	O60934	NBN	P24941	CDK2	T497	W501L	501	Missense	distal	4	no	11.773	12.365	EPSD	COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	O60934	NBN	P24941	CDK2	T497	P498L	498	Missense	proximal	1	no	11.773	1.952	EPSD	COSMIC	8.148	Loss
CMGC_CDK_CDK2_CDK2_ST	O60934	NBN	P24941	CDK2	T497	N503Y	503	Missense	distal	6	no	11.773	11.761	EPSD	COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	O60934	NBN	P24941	CDK2	S499	W501L	501	Missense	proximal	2	no	10.030	9.668	EPSD	COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	O60934	NBN	P24941	CDK2	S499	P498L	498	Missense	proximal	-1	no	10.030	9.851	EPSD	COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	O60934	NBN	P24941	CDK2	S499	N503Y	503	Missense	distal	4	no	10.030	10.250	EPSD	COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	O60934	NBN	P24941	CDK2	S738	L739P	739	Missense	proximal	1	no	1.508	11.329	EPSD	COSMIC	8.148	Gain
CMGC_CDK_CDK2_CDK2_ST	Q6PKG0	LARP1	P24941	CDK2	T649	P650L	650	Missense	proximal	1	no	11.569	1.748	PhosphoSitePlus;EPSD	COSMIC	8.148	Loss
CMGC_CDK_CDK2_CDK2_ST	Q8NBZ0	INO80E	P24941	CDK2	T90	K94E	94	Missense	distal	4	no	13.621	13.236	EPSD	COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	Q8NBZ0	INO80E	P24941	CDK2	S98	P100S	100	Missense	proximal	2	no	12.680	12.747	EPSD	COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	Q8NBZ0	INO80E	P24941	CDK2	S98	K94E	94	Missense	distal	-4	no	12.680	12.991	EPSD	COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	Q8NBZ0	INO80E	P24941	CDK2	S106	P100S	100	Missense	distal	-6	no	10.328	10.327	EPSD	COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	Q8NBZ0	INO80E	P24941	CDK2	S106	S111F	111	Missense	distal	5	no	10.328	10.646	EPSD	COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	Q8NBZ0	INO80E	P24941	CDK2	S127	P128S	128	Missense	proximal	1	no	12.327	1.061	EPSD	COSMIC	8.148	Loss
CMGC_CDK_CDK2_CDK2_ST	Q8NBZ0	INO80E	P24941	CDK2	S127	G124Q	124	Missense	distal	-3	no	12.327	12.281	EPSD	COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	Q8NBZ0	INO80E	P24941	CDK2	S127	S127F	127	Missense	central	0	yes	12.327	0.000	EPSD	COSMIC	8.148	Loss
CMGC_CDK_CDK2_CDK2_ST	Q8NBZ0	INO80E	P24941	CDK2	S154	L156P	156	Missense	proximal	2	no	14.442	14.549	PhosphoSitePlus	COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	Q8NBZ0	INO80E	P24941	CDK2	T201	L203P	203	Missense	proximal	2	no	14.793	14.900	EPSD	COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	Q8NBZ0	INO80E	P24941	CDK2	T201	P204S	204	Missense	distal	3	no	14.793	14.827	EPSD	COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	Q9UPN3	MACF1	P24941	CDK2	S35	G32R	32	Missense	distal	-3	no	15.290	15.375	EPSD	COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	Q9UPN3	MACF1	P24941	CDK2	S35	T42I	42	Missense	distal	7	no	15.290	15.651	EPSD	COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	Q9UPN3	MACF1	P24941	CDK2	S35	P36L	36	Missense	proximal	1	no	15.290	5.469	EPSD	COSMIC	8.148	Loss
CMGC_CDK_CDK2_CDK2_ST	Q9UPN3	MACF1	P24941	CDK2	T212	Y211H	211	Missense	proximal	-1	no	10.890	10.570	EPSD	COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	Q9UPN3	MACF1	P24941	CDK2	S280	V278M	278	Missense	proximal	-2	no	15.487	14.052	EPSD	COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	Q9UPN3	MACF1	P24941	CDK2	S862	S862N	862	Missense	central	0	yes	15.065	0.000	EPSD	COSMIC	8.148	Loss
CMGC_CDK_CDK2_CDK2_ST	Q9UPN3	MACF1	P24941	CDK2	S862	P863L	863	Missense	proximal	1	no	15.065	5.245	EPSD	COSMIC	8.148	Loss
CMGC_CDK_CDK2_CDK2_ST	Q9UPN3	MACF1	P24941	CDK2	S898	R900Q	900	Missense	proximal	2	no	8.562	8.462	EPSD	COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	Q9UPN3	MACF1	P24941	CDK2	S907	A913T	913	Missense	distal	6	no	13.460	13.472	EPSD	COSMIC;GDSC;CCLE	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	Q9UPN3	MACF1	P24941	CDK2	S907	P908H	908	Missense	proximal	1	no	13.460	6.701	EPSD	COSMIC	8.148	Loss
CMGC_CDK_CDK2_CDK2_ST	Q9UPN3	MACF1	P24941	CDK2	S907	R900Q	900	Missense	distal	-7	no	13.460	13.073	EPSD	COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	Q9UPN3	MACF1	P24941	CDK2	S1122	S1122I	1122	Missense	central	0	yes	12.918	0.000	EPSD	COSMIC	8.148	Loss
CMGC_CDK_CDK2_CDK2_ST	Q9UPN3	MACF1	P24941	CDK2	S1363	K1370E	1370	Missense	distal	7	no	9.734	10.065	EPSD	COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	Q9UPN3	MACF1	P24941	CDK2	S1367	R1373C	1373	Missense	distal	6	no	16.855	16.858	EPSD	COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	Q9UPN3	MACF1	P24941	CDK2	S1367	K1370E	1370	Missense	distal	3	no	16.855	14.770	EPSD	COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	Q9UPN3	MACF1	P24941	CDK2	S1367	R1373P	1373	Missense	distal	6	no	16.855	16.871	EPSD	COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	Q9UPN3	MACF1	P24941	CDK2	S2006	Y2003F	2003	Missense	distal	-3	no	13.359	13.431	EPSD	COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	Q9UPN3	MACF1	P24941	CDK2	S2517	I2512T	2512	Missense	distal	-5	no	9.704	9.664	EPSD	COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	Q9UPN3	MACF1	P24941	CDK2	S2517	S2522F	2522	Missense	distal	5	no	9.704	10.023	EPSD	COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	Q9UPN3	MACF1	P24941	CDK2	S2517	S2517F	2517	Missense	central	0	yes	9.704	0.000	EPSD	COSMIC	8.148	Loss
CMGC_CDK_CDK2_CDK2_ST	Q9UPN3	MACF1	P24941	CDK2	T2586	N2588I	2588	Missense	proximal	2	no	8.477	8.525	EPSD	COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	Q9UPN3	MACF1	P24941	CDK2	S2594	N2588I	2588	Missense	distal	-6	no	10.329	10.332	EPSD	COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	Q9UPN3	MACF1	P24941	CDK2	S2926	I2924N	2924	Missense	proximal	-2	no	11.357	10.169	EPSD	COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	Q9UPN3	MACF1	P24941	CDK2	S2926	K2929E	2929	Missense	distal	3	no	11.357	9.272	EPSD	COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	Q9UPN3	MACF1	P24941	CDK2	S3016	I3018V	3018	Missense	proximal	2	no	10.568	10.713	EPSD	COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	Q9UPN3	MACF1	P24941	CDK2	S3020	S3027L	3027	Missense	distal	7	no	8.688	8.870	EPSD	COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	Q9UPN3	MACF1	P24941	CDK2	S3020	I3018V	3018	Missense	proximal	-2	no	8.688	8.192	EPSD	COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	Q9UPN3	MACF1	P24941	CDK2	T3111	H3118Q	3118	Missense	distal	7	no	11.096	10.809	EPSD	COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	Q9UPN3	MACF1	P24941	CDK2	S3298	L3302V	3302	Missense	distal	4	no	15.057	15.172	EPSD	COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	Q9UPN3	MACF1	P24941	CDK2	S3298	P3299L	3299	Missense	proximal	1	no	15.057	5.236	EPSD	COSMIC	8.148	Loss
CMGC_CDK_CDK2_CDK2_ST	Q9UPN3	MACF1	P24941	CDK2	T3323	E3321G	3321	Missense	proximal	-2	no	14.177	14.550	EPSD	COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	Q9UPN3	MACF1	P24941	CDK2	T3323	E3321D	3321	Missense	proximal	-2	no	14.177	15.158	EPSD	COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	Q9UPN3	MACF1	P24941	CDK2	T3323	E3321K	3321	Missense	proximal	-2	no	14.177	14.778	EPSD	COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	Q9UPN3	MACF1	P24941	CDK2	S3657	D3658G	3658	Missense	proximal	1	no	8.245	9.177	EPSD	COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	Q9UPN3	MACF1	P24941	CDK2	S3657	K3654N	3654	Missense	distal	-3	no	8.245	8.306	EPSD	COSMIC;CCLE	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	Q9UPN3	MACF1	P24941	CDK2	S3692	R3694C	3694	Missense	proximal	2	no	13.892	13.879	EPSD	COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	Q9UPN3	MACF1	P24941	CDK2	S3692	L3691F	3691	Missense	proximal	-1	no	13.892	14.857	EPSD	COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	Q9UPN3	MACF1	P24941	CDK2	S3914	S3914L	3914	Missense	central	0	yes	13.081	0.000	EPSD	COSMIC	8.148	Loss
CMGC_CDK_CDK2_CDK2_ST	Q9UPN3	MACF1	P24941	CDK2	S3914	S3914G	3914	Missense	central	0	yes	13.081	0.000	EPSD	COSMIC	8.148	Loss
CMGC_CDK_CDK2_CDK2_ST	Q9UPN3	MACF1	P24941	CDK2	S3914	G3912S	3912	Missense	proximal	-2	no	13.081	13.173	EPSD	COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	Q9UPN3	MACF1	P24941	CDK2	S3914	T3917I	3917	Missense	distal	3	no	13.081	12.528	EPSD	COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	Q9UPN3	MACF1	P24941	CDK2	S3914	P3919L	3919	Missense	distal	5	no	13.081	13.121	EPSD	COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	Q9UPN3	MACF1	P24941	CDK2	S3914	L3918I	3918	Missense	distal	4	no	13.081	12.941	EPSD	COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	Q9UPN3	MACF1	P24941	CDK2	S3914	G3911E	3911	Missense	distal	-3	no	13.081	13.153	EPSD	COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	Q9UPN3	MACF1	P24941	CDK2	S3914	S3920F	3920	Missense	distal	6	no	13.081	13.062	EPSD	COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	Q9UPN3	MACF1	P24941	CDK2	S3914	S3913I	3913	Missense	proximal	-1	no	13.081	13.535	EPSD	COSMIC;CCLE	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	Q9UPN3	MACF1	P24941	CDK2	T3917	S3914L	3914	Missense	distal	-3	no	8.529	8.363	EPSD	COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	Q9UPN3	MACF1	P24941	CDK2	T3917	S3914G	3914	Missense	distal	-3	no	8.529	8.538	EPSD	COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	Q9UPN3	MACF1	P24941	CDK2	T3917	G3912S	3912	Missense	distal	-5	no	8.529	8.405	EPSD	COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	Q9UPN3	MACF1	P24941	CDK2	T3917	T3917I	3917	Missense	central	0	yes	8.529	0.000	EPSD	COSMIC	8.148	Loss
CMGC_CDK_CDK2_CDK2_ST	Q9UPN3	MACF1	P24941	CDK2	T3917	P3919L	3919	Missense	proximal	2	no	8.529	8.423	EPSD	COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	Q9UPN3	MACF1	P24941	CDK2	T3917	L3918I	3918	Missense	proximal	1	no	8.529	4.230	EPSD	COSMIC	8.148	Loss
CMGC_CDK_CDK2_CDK2_ST	Q9UPN3	MACF1	P24941	CDK2	T3917	K3923N	3923	Missense	distal	6	no	8.529	8.525	EPSD	COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	Q9UPN3	MACF1	P24941	CDK2	T3917	S3920F	3920	Missense	distal	3	no	8.529	8.454	EPSD	COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	Q9UPN3	MACF1	P24941	CDK2	T3917	S3913I	3913	Missense	distal	-4	no	8.529	8.024	EPSD	COSMIC;CCLE	8.148	Loss
CMGC_CDK_CDK2_CDK2_ST	Q9UPN3	MACF1	P24941	CDK2	S4496	K4489Q	4489	Missense	distal	-7	no	13.903	13.907	EPSD	COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	Q9UPN3	MACF1	P24941	CDK2	S4509	N4510H	4510	Missense	proximal	1	no	-25.694	8.159	EPSD	COSMIC	8.148	Gain
CMGC_CDK_CDK2_CDK2_ST	Q9UPN3	MACF1	P24941	CDK2	S4521	E4516V	4516	Missense	distal	-5	no	13.515	13.509	EPSD	COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	Q9UPN3	MACF1	P24941	CDK2	S4521	P4522A	4522	Missense	proximal	1	no	13.515	-0.888	EPSD	COSMIC	8.148	Loss
CMGC_CDK_CDK2_CDK2_ST	Q9UPN3	MACF1	P24941	CDK2	S4521	Q4519H	4519	Missense	proximal	-2	no	13.515	13.072	EPSD	COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	Q9UPN3	MACF1	P24941	CDK2	S4521	E4518K	4518	Missense	distal	-3	no	13.515	13.300	EPSD	COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	Q9UPN3	MACF1	P24941	CDK2	S4521	K4523N	4523	Missense	proximal	2	no	13.515	13.586	EPSD	COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	Q9UPN3	MACF1	P24941	CDK2	S5592	P5599S	5599	Missense	distal	7	no	13.211	13.059	EPSD	COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	Q9UPN3	MACF1	P24941	CDK2	S5808	L5806F	5806	Missense	proximal	-2	no	11.908	11.019	EPSD	COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	Q9UPN3	MACF1	P24941	CDK2	S5888	V5887M	5887	Missense	proximal	-1	no	7.084	8.177	EPSD	COSMIC	8.148	Gain
CMGC_CDK_CDK2_CDK2_ST	Q9UPN3	MACF1	P24941	CDK2	S6408	S6410T	6410	Missense	proximal	2	no	11.155	10.911	EPSD	COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	Q9UPN3	MACF1	P24941	CDK2	T6972	I6978V	6978	Missense	distal	6	no	11.151	11.150	EPSD	COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	Q9UPN3	MACF1	P24941	CDK2	T6972	P6977L	6977	Missense	distal	5	no	11.151	11.191	EPSD	COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	Q9UPN3	MACF1	P24941	CDK2	T6972	P6973S	6973	Missense	proximal	1	no	11.151	-0.114	EPSD	COSMIC	8.148	Loss
CMGC_CDK_CDK2_CDK2_ST	Q9UPN3	MACF1	P24941	CDK2	T6972	P6974L	6974	Missense	proximal	2	no	11.151	11.045	EPSD	COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	Q9UPN3	MACF1	P24941	CDK2	T6972	P6977T	6977	Missense	distal	5	no	11.151	11.126	EPSD	COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	Q9UPN3	MACF1	P24941	CDK2	T6972	P6977S	6977	Missense	distal	5	no	11.151	11.051	EPSD	COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	Q9UPN3	MACF1	P24941	CDK2	T6972	L6968V	6968	Missense	distal	-4	no	11.151	11.162	EPSD	COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	Q9UPN3	MACF1	P24941	CDK2	T7213	G7219D	7219	Missense	distal	6	no	15.589	15.585	PhosphoSitePlus	COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	Q9UPN3	MACF1	P24941	CDK2	T7213	A7208T	7208	Missense	distal	-5	no	15.589	15.563	PhosphoSitePlus	COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	Q9UPN3	MACF1	P24941	CDK2	T7213	G7207C	7207	Missense	distal	-6	no	15.589	15.592	PhosphoSitePlus	COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	Q9UPN3	MACF1	P24941	CDK2	S7230	P7231L	7231	Missense	proximal	1	no	15.485	5.664	EPSD	COSMIC	8.148	Loss
CMGC_CDK_CDK2_CDK2_ST	Q9UPN3	MACF1	P24941	CDK2	S7230	P7231T	7231	Missense	proximal	1	no	15.485	5.528	EPSD	COSMIC	8.148	Loss
CMGC_CDK_CDK2_CDK2_ST	Q9UPN3	MACF1	P24941	CDK2	S7230	P7231A	7231	Missense	proximal	1	no	15.485	1.082	EPSD	COSMIC	8.148	Loss
CMGC_CDK_CDK2_CDK2_ST	Q9UPN3	MACF1	P24941	CDK2	S7230	S7235N	7235	Missense	distal	5	no	15.485	15.689	EPSD	COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	Q9UPN3	MACF1	P24941	CDK2	S7251	T7254P	7254	Missense	distal	3	no	14.261	14.375	EPSD	COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	Q9UPN3	MACF1	P24941	CDK2	T7254	T7254P	7254	Missense	central	0	yes	12.488	0.000	EPSD	COSMIC	8.148	Loss
CMGC_CDK_CDK2_CDK2_ST	Q9UPN3	MACF1	P24941	CDK2	T7273	H7277P	7277	Missense	distal	4	no	11.902	12.140	EPSD	COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	Q9UPN3	MACF1	P24941	CDK2	T7273	H7277Y	7277	Missense	distal	4	no	11.902	12.339	EPSD	COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	Q9UPN3	MACF1	P24941	CDK2	T7273	P7272L	7272	Missense	proximal	-1	no	11.902	11.723	EPSD	COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	Q9UPN3	MACF1	P24941	CDK2	T7273	R7280Q	7280	Missense	distal	7	no	11.902	11.258	EPSD	COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	Q9UPN3	MACF1	P24941	CDK2	T7273	T7273I	7273	Missense	central	0	yes	11.902	0.000	EPSD	COSMIC	8.148	Loss
CMGC_CDK_CDK2_CDK2_ST	Q9UPN3	MACF1	P24941	CDK2	T7273	R7271C	7271	Missense	proximal	-2	no	11.902	12.077	EPSD	COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	Q9UPN3	MACF1	P24941	CDK2	S7292	P7293L	7293	Missense	proximal	1	no	15.178	5.357	EPSD	COSMIC	8.148	Loss
CMGC_CDK_CDK2_CDK2_ST	Q9UPN3	MACF1	P24941	CDK2	S7292	A7294V	7294	Missense	proximal	2	no	15.178	15.276	EPSD	COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	Q9UPN3	MACF1	P24941	CDK2	S7292	D7286N	7286	Missense	distal	-6	no	15.178	15.179	EPSD	COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	Q9UPN3	MACF1	P24941	CDK2	S7292	D7286Y	7286	Missense	distal	-6	no	15.178	15.179	EPSD	COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	Q9UPN3	MACF1	P24941	CDK2	T7296	P7293L	7293	Missense	distal	-3	no	10.481	10.410	EPSD	COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	Q9UPN3	MACF1	P24941	CDK2	T7296	A7294V	7294	Missense	proximal	-2	no	10.481	9.815	EPSD	COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	Q9UPN3	MACF1	P24941	CDK2	T7296	R7302W	7302	Missense	distal	6	no	10.481	10.473	EPSD	COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	Q9UPN3	MACF1	P24941	CDK2	S7310	R7311H	7311	Missense	proximal	1	no	5.398	8.437	EPSD	COSMIC;CCLE	8.148	Gain
CMGC_CDK_CDK2_CDK2_ST	Q9UPN3	MACF1	P24941	CDK2	S7380	T7377I	7377	Missense	distal	-3	no	15.816	15.876	EPSD	COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	Q9UPN3	MACF1	P24941	CDK2	S7380	R7382K	7382	Missense	proximal	2	no	15.816	15.516	EPSD	COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	Q9UPN3	MACF1	P24941	CDK2	T7383	T7377I	7377	Missense	distal	-6	no	16.357	16.359	EPSD	COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	Q9UPN3	MACF1	P24941	CDK2	T7383	R7382K	7382	Missense	proximal	-1	no	16.357	15.686	EPSD	COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	Q03252	LMNB2	P24941	CDK2	S90	V89L	89	Missense	proximal	-1	no	10.082	9.946	EPSD	COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	Q03252	LMNB2	P24941	CDK2	S405	P408L	408	Missense	distal	3	no	11.285	10.901	EPSD	COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	Q03252	LMNB2	P24941	CDK2	S407	P408L	408	Missense	proximal	1	no	13.039	3.218	EPSD	COSMIC	8.148	Loss
CMGC_CDK_CDK2_CDK2_ST	Q03252	LMNB2	P24941	CDK2	T518	I522F	522	Missense	distal	4	no	11.843	11.689	EPSD	COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	Q03252	LMNB2	P24941	CDK2	T518	A525T	525	Missense	distal	7	no	11.843	11.154	EPSD	COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	Q03252	LMNB2	P24941	CDK2	T518	F517L	517	Missense	proximal	-1	no	11.843	10.878	EPSD	COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	Q03252	LMNB2	P24941	CDK2	T518	T518M	518	Missense	central	0	yes	11.843	0.000	EPSD	COSMIC	8.148	Loss
CMGC_CDK_CDK2_CDK2_ST	Q03252	LMNB2	P24941	CDK2	S541	S541C	541	Missense	central	0	yes	15.989	0.000	EPSD	COSMIC	8.148	Loss
CMGC_CDK_CDK2_CDK2_ST	Q03252	LMNB2	P24941	CDK2	S541	S544L	544	Missense	distal	3	no	15.989	15.571	EPSD	COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	Q03252	LMNB2	P24941	CDK2	S541	S541G	541	Missense	central	0	yes	15.989	0.000	EPSD	COSMIC	8.148	Loss
CMGC_CDK_CDK2_CDK2_ST	P33993	MCM7	P24941	CDK2	S121	R120Q	120	Missense	proximal	-1	no	14.179	13.301	PhosphoSitePlus;EPSD	COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	P33993	MCM7	P24941	CDK2	S410	G413E	413	Missense	distal	3	no	7.708	8.431	EPSD	COSMIC	8.148	Gain
CMGC_CDK_CDK2_CDK2_ST	Q9UIF9	BAZ2A	P24941	CDK2	S21	S26F	26	Missense	distal	5	no	8.645	8.963	EPSD	COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	Q9UIF9	BAZ2A	P24941	CDK2	S21	A20D	20	Missense	proximal	-1	no	8.645	9.671	EPSD	COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	Q9UIF9	BAZ2A	P24941	CDK2	S26	S26F	26	Missense	central	0	yes	14.162	0.000	EPSD	COSMIC	8.148	Loss
CMGC_CDK_CDK2_CDK2_ST	Q9UIF9	BAZ2A	P24941	CDK2	S26	A20D	20	Missense	distal	-6	no	14.162	14.161	EPSD	COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	Q9UIF9	BAZ2A	P24941	CDK2	S26	G30V	30	Missense	distal	4	no	14.162	14.509	EPSD	COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	Q9UIF9	BAZ2A	P24941	CDK2	S26	E31K	31	Missense	distal	5	no	14.162	14.029	EPSD	COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	Q9UIF9	BAZ2A	P24941	CDK2	S26	L33F	33	Missense	distal	7	no	14.162	14.833	EPSD	COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	Q9UIF9	BAZ2A	P24941	CDK2	S38	E31K	31	Missense	distal	-7	no	14.496	14.359	EPSD	COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	Q9UIF9	BAZ2A	P24941	CDK2	S38	P43H	43	Missense	distal	5	no	14.496	14.574	EPSD	COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	Q9UIF9	BAZ2A	P24941	CDK2	S38	L33F	33	Missense	distal	-5	no	14.496	14.557	EPSD	COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	Q9UIF9	BAZ2A	P24941	CDK2	S135	Q132L	132	Missense	distal	-3	no	13.535	13.406	EPSD	COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	Q9UIF9	BAZ2A	P24941	CDK2	S135	L142F	142	Missense	distal	7	no	13.535	14.206	EPSD	COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	Q9UIF9	BAZ2A	P24941	CDK2	S135	Q132E	132	Missense	distal	-3	no	13.535	13.651	EPSD	COSMIC;GDSC;CCLE	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	Q9UIF9	BAZ2A	P24941	CDK2	S156	N161Y	161	Missense	distal	5	no	15.908	15.878	EPSD	COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	Q9UIF9	BAZ2A	P24941	CDK2	S367	T360S	360	Missense	distal	-7	no	9.866	9.689	EPSD	COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	Q9UIF9	BAZ2A	P24941	CDK2	S367	A366T	366	Missense	proximal	-1	no	9.866	9.873	EPSD	COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	Q9UIF9	BAZ2A	P24941	CDK2	S370	A366T	366	Missense	distal	-4	no	15.160	15.385	EPSD	COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	Q9UIF9	BAZ2A	P24941	CDK2	S492	V498I	498	Missense	distal	6	no	11.721	11.723	EPSD	COSMIC;GDSC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	Q9UIF9	BAZ2A	P24941	CDK2	S492	P485L	485	Missense	distal	-7	no	11.721	11.727	EPSD	COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	Q9UIF9	BAZ2A	P24941	CDK2	S492	K494Q	494	Missense	proximal	2	no	11.721	11.922	EPSD	COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	Q9UIF9	BAZ2A	P24941	CDK2	S492	P497L	497	Missense	distal	5	no	11.721	11.761	EPSD	COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	Q9UIF9	BAZ2A	P24941	CDK2	S496	V498I	498	Missense	proximal	2	no	13.083	12.937	EPSD	COSMIC;GDSC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	Q9UIF9	BAZ2A	P24941	CDK2	S496	A502S	502	Missense	distal	6	no	13.083	13.088	EPSD	COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	Q9UIF9	BAZ2A	P24941	CDK2	S496	K494Q	494	Missense	proximal	-2	no	13.083	13.030	EPSD	COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	Q9UIF9	BAZ2A	P24941	CDK2	S496	P497L	497	Missense	proximal	1	no	13.083	3.262	EPSD	COSMIC	8.148	Loss
CMGC_CDK_CDK2_CDK2_ST	Q9UIF9	BAZ2A	P24941	CDK2	S500	V498I	498	Missense	proximal	-2	no	11.090	11.586	EPSD	COSMIC;GDSC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	Q9UIF9	BAZ2A	P24941	CDK2	S500	A502S	502	Missense	proximal	2	no	11.090	11.132	EPSD	COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	Q9UIF9	BAZ2A	P24941	CDK2	S500	K494Q	494	Missense	distal	-6	no	11.090	11.093	EPSD	COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	Q9UIF9	BAZ2A	P24941	CDK2	S500	P497L	497	Missense	distal	-3	no	11.090	11.019	EPSD	COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	Q9UIF9	BAZ2A	P24941	CDK2	S509	A502S	502	Missense	distal	-7	no	14.470	14.126	PhosphoSitePlus	COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	Q9UIF9	BAZ2A	P24941	CDK2	T548	R543H	543	Missense	distal	-5	no	13.987	13.988	EPSD	COSMIC;CCLE	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	Q9UIF9	BAZ2A	P24941	CDK2	T548	E550V	550	Missense	proximal	2	no	13.987	14.013	EPSD	COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	Q9UIF9	BAZ2A	P24941	CDK2	T548	R545H	545	Missense	distal	-3	no	13.987	13.945	EPSD	COSMIC;GDSC;CCLE	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	Q9UIF9	BAZ2A	P24941	CDK2	S613	R607Q	607	Missense	distal	-6	no	15.705	15.706	EPSD	COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	Q9UIF9	BAZ2A	P24941	CDK2	S1184	R1187Q	1187	Missense	distal	3	no	15.765	14.021	EPSD	COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	Q9UIF9	BAZ2A	P24941	CDK2	S1184	R1191Q	1191	Missense	distal	7	no	15.765	15.120	EPSD	COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	Q9UIF9	BAZ2A	P24941	CDK2	S1184	R1189Q	1189	Missense	distal	5	no	15.765	15.618	EPSD	COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	Q9UIF9	BAZ2A	P24941	CDK2	S1184	S1184C	1184	Missense	central	0	yes	15.765	0.000	EPSD	COSMIC	8.148	Loss
CMGC_CDK_CDK2_CDK2_ST	Q9UIF9	BAZ2A	P24941	CDK2	S1207	M1200V	1200	Missense	distal	-7	no	14.629	14.147	EPSD	COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	Q9UIF9	BAZ2A	P24941	CDK2	S1207	P1208L	1208	Missense	proximal	1	no	14.629	4.808	EPSD	COSMIC	8.148	Loss
CMGC_CDK_CDK2_CDK2_ST	Q9UIF9	BAZ2A	P24941	CDK2	S1207	G1211D	1211	Missense	distal	4	no	14.629	14.683	EPSD	COSMIC;CCLE	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	Q9UIF9	BAZ2A	P24941	CDK2	S1350	P1347L	1347	Missense	distal	-3	no	13.583	13.512	EPSD	COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	Q9UIF9	BAZ2A	P24941	CDK2	S1350	P1349L	1349	Missense	proximal	-1	no	13.583	13.403	EPSD	COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	Q9UIF9	BAZ2A	P24941	CDK2	S1350	S1343F	1343	Missense	distal	-7	no	13.583	14.134	EPSD	COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	Q9UIF9	BAZ2A	P24941	CDK2	S1370	S1375Y	1375	Missense	distal	5	no	12.068	12.242	EPSD	COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	Q9UIF9	BAZ2A	P24941	CDK2	S1370	A1365S	1365	Missense	distal	-5	no	12.068	11.999	EPSD	COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	Q9UIF9	BAZ2A	P24941	CDK2	S1370	P1368L	1368	Missense	proximal	-2	no	12.068	11.843	EPSD	COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	Q9UIF9	BAZ2A	P24941	CDK2	T1377	S1375Y	1375	Missense	proximal	-2	no	13.296	13.383	EPSD	COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	Q9UIF9	BAZ2A	P24941	CDK2	S1397	P1395L	1395	Missense	proximal	-2	no	14.426	14.201	EPSD	COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	Q9UIF9	BAZ2A	P24941	CDK2	S1397	P1391T	1391	Missense	distal	-6	no	14.426	14.425	EPSD	COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	Q9UIF9	BAZ2A	P24941	CDK2	S1397	Q1396H	1396	Missense	proximal	-1	no	14.426	14.853	EPSD	COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	Q9UIF9	BAZ2A	P24941	CDK2	S1531	Q1526H	1526	Missense	distal	-5	no	8.553	8.600	EPSD	COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	Q9UIF9	BAZ2A	P24941	CDK2	S1531	R1536W	1536	Missense	distal	5	no	8.553	8.720	EPSD	COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	Q9UIF9	BAZ2A	P24941	CDK2	S1531	L1533M	1533	Missense	proximal	2	no	8.553	8.871	EPSD	COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	Q9UIF9	BAZ2A	P24941	CDK2	S1542	R1547H	1547	Missense	distal	5	no	13.507	13.479	EPSD	COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	Q9UIF9	BAZ2A	P24941	CDK2	S1542	R1536W	1536	Missense	distal	-6	no	13.507	13.513	EPSD	COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	Q9UIF9	BAZ2A	P24941	CDK2	S1545	R1547H	1547	Missense	proximal	2	no	9.024	8.943	EPSD	COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	Q9UIF9	BAZ2A	P24941	CDK2	T1621	G1628D	1628	Missense	distal	7	no	12.990	13.007	EPSD	COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	Q9UIF9	BAZ2A	P24941	CDK2	S1770	A1773T	1773	Missense	distal	3	no	10.776	11.174	EPSD	COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	Q9UIF9	BAZ2A	P24941	CDK2	S1783	R1787Q	1787	Missense	distal	4	no	17.831	18.013	EPSD	COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	Q9UIF9	BAZ2A	P24941	CDK2	S1783	P1784T	1784	Missense	proximal	1	no	17.831	7.874	EPSD	COSMIC	8.148	Loss
CMGC_CDK_CDK2_CDK2_ST	P22234	PAICS	P24941	CDK2	S27	G29A	29	Missense	proximal	2	no	18.378	18.285	PhosphoSitePlus	COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	P22234	PAICS	P24941	CDK2	T105	L109F	109	Missense	distal	4	no	8.910	8.616	EPSD	COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	P22234	PAICS	P24941	CDK2	T105	T105I	105	Missense	central	0	yes	8.910	0.000	EPSD	COSMIC	8.148	Loss
CMGC_CDK_CDK2_CDK2_ST	P22234	PAICS	P24941	CDK2	T105	R102K	102	Missense	distal	-3	no	8.910	8.681	EPSD	COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	P22234	PAICS	P24941	CDK2	T105	I103T	103	Missense	proximal	-2	no	8.910	9.031	EPSD	COSMIC;GDSC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	P22234	PAICS	P24941	CDK2	S223	D221N	221	Missense	proximal	-2	no	9.365	8.157	EPSD	COSMIC;CCLE	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	P22234	PAICS	P24941	CDK2	S223	G220E	220	Missense	distal	-3	no	9.365	9.436	EPSD	COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	P22234	PAICS	P24941	CDK2	S223	R222Q	222	Missense	proximal	-1	no	9.365	8.487	EPSD	COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	P22234	PAICS	P24941	CDK2	S223	Q229H	229	Missense	distal	6	no	9.365	9.354	EPSD	COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	P22234	PAICS	P24941	CDK2	S223	D221A	221	Missense	proximal	-2	no	9.365	9.516	EPSD	COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	P22234	PAICS	P24941	CDK2	S223	D227E	227	Missense	distal	4	no	9.365	9.447	EPSD	COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	P22234	PAICS	P24941	CDK2	S264	C266Y	266	Missense	proximal	2	no	10.235	10.147	EPSD	COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	P22234	PAICS	P24941	CDK2	S264	E257K	257	Missense	distal	-7	no	10.235	10.097	EPSD	COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	P22234	PAICS	P24941	CDK2	S264	L260F	260	Missense	distal	-4	no	10.235	9.685	EPSD	COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	P22234	PAICS	P24941	CDK2	T354	W357G	357	Missense	distal	3	no	11.469	12.289	EPSD	COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	P22234	PAICS	P24941	CDK2	T354	P355Q	355	Missense	proximal	1	no	11.469	3.557	EPSD	COSMIC	8.148	Loss
CMGC_CDK_CDK2_CDK2_ST	P22234	PAICS	P24941	CDK2	T354	P355L	355	Missense	proximal	1	no	11.469	1.648	EPSD	COSMIC;CCLE	8.148	Loss
CMGC_CDK_CDK2_CDK2_ST	Q6Y7W6	GIGYF2	P24941	CDK2	S158	S160I	160	Missense	proximal	2	no	8.312	8.223	EPSD	COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	Q6Y7W6	GIGYF2	P24941	CDK2	S199	E200D	200	Missense	proximal	1	no	7.982	8.904	EPSD	COSMIC	8.148	Gain
CMGC_CDK_CDK2_CDK2_ST	Q6Y7W6	GIGYF2	P24941	CDK2	S236	R241H	241	Missense	distal	5	no	15.266	15.237	EPSD	COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	Q6Y7W6	GIGYF2	P24941	CDK2	S236	G239D	239	Missense	distal	3	no	15.266	13.553	EPSD	COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	Q6Y7W6	GIGYF2	P24941	CDK2	S273	R266H	266	Missense	distal	-7	no	10.054	9.833	EPSD	COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	Q6Y7W6	GIGYF2	P24941	CDK2	S273	R266C	266	Missense	distal	-7	no	10.054	9.981	EPSD	COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	Q6Y7W6	GIGYF2	P24941	CDK2	S273	S273C	273	Missense	central	0	yes	10.054	0.000	EPSD	COSMIC	8.148	Loss
CMGC_CDK_CDK2_CDK2_ST	Q6Y7W6	GIGYF2	P24941	CDK2	S273	G274V	274	Missense	proximal	1	no	10.054	0.454	EPSD	COSMIC	8.148	Loss
CMGC_CDK_CDK2_CDK2_ST	Q6Y7W6	GIGYF2	P24941	CDK2	S273	R272H	272	Missense	proximal	-1	no	10.054	9.603	EPSD	COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	Q6Y7W6	GIGYF2	P24941	CDK2	S273	R269Q	269	Missense	distal	-4	no	10.054	10.079	EPSD	COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	Q6Y7W6	GIGYF2	P24941	CDK2	S273	R272C	272	Missense	proximal	-1	no	10.054	9.356	EPSD	COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	Q6Y7W6	GIGYF2	P24941	CDK2	S275	S273C	273	Missense	proximal	-2	no	9.577	9.166	EPSD	COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	Q6Y7W6	GIGYF2	P24941	CDK2	S275	G274V	274	Missense	proximal	-1	no	9.577	8.485	EPSD	COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	Q6Y7W6	GIGYF2	P24941	CDK2	S275	R272H	272	Missense	distal	-3	no	9.577	9.534	EPSD	COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	Q6Y7W6	GIGYF2	P24941	CDK2	S275	R269Q	269	Missense	distal	-6	no	9.577	9.578	EPSD	COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	Q6Y7W6	GIGYF2	P24941	CDK2	S275	R272C	272	Missense	distal	-3	no	9.577	9.491	EPSD	COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	Q6Y7W6	GIGYF2	P24941	CDK2	S303	M297T	297	Missense	distal	-6	no	8.359	8.351	EPSD	COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	Q6Y7W6	GIGYF2	P24941	CDK2	S303	F300L	300	Missense	distal	-3	no	8.359	8.101	EPSD	COSMIC	8.148	Loss
CMGC_CDK_CDK2_CDK2_ST	Q6Y7W6	GIGYF2	P24941	CDK2	S340	G339V	339	Missense	proximal	-1	no	8.743	7.652	EPSD	COSMIC	8.148	Loss
CMGC_CDK_CDK2_CDK2_ST	Q6Y7W6	GIGYF2	P24941	CDK2	S340	N342S	342	Missense	proximal	2	no	8.743	8.880	EPSD	COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	Q6Y7W6	GIGYF2	P24941	CDK2	S340	S337F	337	Missense	distal	-3	no	8.743	8.835	EPSD	COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	Q6Y7W6	GIGYF2	P24941	CDK2	T370	P371L	371	Missense	proximal	1	no	13.001	3.180	EPSD	COSMIC	8.148	Loss
CMGC_CDK_CDK2_CDK2_ST	Q6Y7W6	GIGYF2	P24941	CDK2	T370	S367N	367	Missense	distal	-3	no	13.001	12.927	EPSD	COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	Q6Y7W6	GIGYF2	P24941	CDK2	T382	G381A	381	Missense	proximal	-1	no	11.080	9.761	EPSD	COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	Q6Y7W6	GIGYF2	P24941	CDK2	T382	P383L	383	Missense	proximal	1	no	11.080	1.259	EPSD	COSMIC	8.148	Loss
CMGC_CDK_CDK2_CDK2_ST	Q6Y7W6	GIGYF2	P24941	CDK2	T382	G381C	381	Missense	proximal	-1	no	11.080	9.904	EPSD	COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	Q6Y7W6	GIGYF2	P24941	CDK2	T382	R379K	379	Missense	distal	-3	no	11.080	10.851	EPSD	COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	Q6Y7W6	GIGYF2	P24941	CDK2	T382	S388N	388	Missense	distal	6	no	11.080	11.082	EPSD	COSMIC;GDSC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	Q6Y7W6	GIGYF2	P24941	CDK2	S593	P594L	594	Missense	proximal	1	no	14.218	4.397	EPSD;PhosphoSitePlus	COSMIC	8.148	Loss
CMGC_CDK_CDK2_CDK2_ST	Q6Y7W6	GIGYF2	P24941	CDK2	S593	P600L	600	Missense	distal	7	no	14.218	14.248	EPSD;PhosphoSitePlus	COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	Q6Y7W6	GIGYF2	P24941	CDK2	S593	P599S	599	Missense	distal	6	no	14.218	14.219	EPSD;PhosphoSitePlus	COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	Q6Y7W6	GIGYF2	P24941	CDK2	S593	M586L	586	Missense	distal	-7	no	14.218	13.722	EPSD;PhosphoSitePlus	COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	Q6Y7W6	GIGYF2	P24941	CDK2	S593	P598L	598	Missense	distal	5	no	14.218	14.258	EPSD;PhosphoSitePlus	COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	Q6Y7W6	GIGYF2	P24941	CDK2	S593	W587C	587	Missense	distal	-6	no	14.218	14.215	EPSD;PhosphoSitePlus	COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	Q6Y7W6	GIGYF2	P24941	CDK2	S593	P594S	594	Missense	proximal	1	no	14.218	2.952	EPSD;PhosphoSitePlus	COSMIC	8.148	Loss
CMGC_CDK_CDK2_CDK2_ST	Q6Y7W6	GIGYF2	P24941	CDK2	S593	P591S	591	Missense	proximal	-2	no	14.218	13.567	EPSD;PhosphoSitePlus	COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	Q6Y7W6	GIGYF2	P24941	CDK2	S593	G595S	595	Missense	proximal	2	no	14.218	14.167	EPSD;PhosphoSitePlus	COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	Q6Y7W6	GIGYF2	P24941	CDK2	S593	G588R	588	Missense	distal	-5	no	14.218	14.185	EPSD;PhosphoSitePlus	COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	Q9NXR1	NDE1	P24941	CDK2	T191	M193I	193	Missense	proximal	2	no	12.949	12.715	EPSD	COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	Q9NXR1	NDE1	P24941	CDK2	T191	P189H	189	Missense	proximal	-2	no	12.949	11.939	EPSD	COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	Q9NXR1	NDE1	P24941	CDK2	T215	T215M	215	Missense	central	0	yes	13.557	0.000	EPSD	COSMIC	8.148	Loss
CMGC_CDK_CDK2_CDK2_ST	Q9NXR1	NDE1	P24941	CDK2	T215	S214F	214	Missense	proximal	-1	no	13.557	14.813	EPSD	COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	Q9NXR1	NDE1	P24941	CDK2	T228	S225N	225	Missense	distal	-3	no	14.584	14.510	PhosphoSitePlus	COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	Q9NXR1	NDE1	P24941	CDK2	T228	S223N	223	Missense	distal	-5	no	14.584	14.648	PhosphoSitePlus	COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	Q9NXR1	NDE1	P24941	CDK2	T243	P244S	244	Missense	proximal	1	no	14.404	3.138	EPSD	COSMIC	8.148	Loss
CMGC_CDK_CDK2_CDK2_ST	Q9NXR1	NDE1	P24941	CDK2	T246	P244S	244	Missense	proximal	-2	no	12.046	11.395	EPSD	COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	Q9NXR1	NDE1	P24941	CDK2	S282	R275Q	275	Missense	distal	-7	no	15.846	15.460	EPSD	COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	Q9NXR1	NDE1	P24941	CDK2	T286	R293Q	293	Missense	distal	7	no	8.340	7.696	EPSD	COSMIC	8.148	Loss
CMGC_CDK_CDK2_CDK2_ST	Q9NXR1	NDE1	P24941	CDK2	T286	R293W	293	Missense	distal	7	no	8.340	8.740	EPSD	COSMIC;CCLE	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	Q9NXR1	NDE1	P24941	CDK2	S328	S331P	331	Missense	distal	3	no	9.306	9.272	EPSD	COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	Q9NXR1	NDE1	P24941	CDK2	S333	S331P	331	Missense	proximal	-2	no	13.283	13.934	EPSD	COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	Q8WUM0	NUP133	P24941	CDK2	S7	P11L	11	Missense	distal	4	no	13.860	13.972	EPSD	COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	Q8WUM0	NUP133	P24941	CDK2	T10	P11L	11	Missense	proximal	1	no	11.733	1.912	EPSD	COSMIC	8.148	Loss
CMGC_CDK_CDK2_CDK2_ST	Q8WUM0	NUP133	P24941	CDK2	T10	S15F	15	Missense	distal	5	no	11.733	12.051	EPSD	COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	Q8WUM0	NUP133	P24941	CDK2	T13	P11L	11	Missense	proximal	-2	no	8.605	8.380	EPSD	COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	Q8WUM0	NUP133	P24941	CDK2	T13	S15F	15	Missense	proximal	2	no	8.605	8.789	EPSD	COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	Q8WUM0	NUP133	P24941	CDK2	T28	T31M	31	Missense	distal	3	no	11.885	11.760	EPSD	COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	Q8WUM0	NUP133	P24941	CDK2	S45	V52D	52	Missense	distal	7	no	12.378	12.806	EPSD	COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	Q8WUM0	NUP133	P24941	CDK2	S45	S44C	44	Missense	proximal	-1	no	12.378	12.722	EPSD	COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	Q8WUM0	NUP133	P24941	CDK2	S45	G40W	40	Missense	distal	-5	no	12.378	12.433	EPSD	COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	Q8WUM0	NUP133	P24941	CDK2	S50	V52D	52	Missense	proximal	2	no	15.047	14.921	PhosphoSitePlus	COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	Q8WUM0	NUP133	P24941	CDK2	S50	G53V	53	Missense	distal	3	no	15.047	15.756	PhosphoSitePlus	COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	Q8WUM0	NUP133	P24941	CDK2	S50	S44C	44	Missense	distal	-6	no	15.047	15.053	PhosphoSitePlus	COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	Q8WUM0	NUP133	P24941	CDK2	S131	S137P	137	Missense	distal	6	no	13.527	13.526	EPSD	COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	Q8WUM0	NUP133	P24941	CDK2	S267	P268T	268	Missense	proximal	1	no	9.034	-0.923	EPSD	COSMIC	8.148	Loss
CMGC_CDK_CDK2_CDK2_ST	Q8WUM0	NUP133	P24941	CDK2	S267	L266F	266	Missense	proximal	-1	no	9.034	9.999	EPSD	COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	Q8WUM0	NUP133	P24941	CDK2	S267	S261F	261	Missense	distal	-6	no	9.034	9.039	EPSD	COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	Q8WUM0	NUP133	P24941	CDK2	S553	L557P	557	Missense	distal	4	no	8.545	8.433	EPSD	COSMIC;GDSC;CCLE	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	Q8WUM0	NUP133	P24941	CDK2	T632	T636A	636	Missense	distal	4	no	12.587	12.344	EPSD	COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	Q8WUM0	NUP133	P24941	CDK2	T632	A635V	635	Missense	distal	3	no	12.587	13.707	EPSD	COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	Q8WUM0	NUP133	P24941	CDK2	T632	R637Q	637	Missense	distal	5	no	12.587	12.441	EPSD	COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	Q8WUM0	NUP133	P24941	CDK2	T632	G631W	631	Missense	proximal	-1	no	12.587	12.663	EPSD	COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	Q8WUM0	NUP133	P24941	CDK2	T632	P633S	633	Missense	proximal	1	no	12.587	1.321	EPSD	COSMIC	8.148	Loss
CMGC_CDK_CDK2_CDK2_ST	Q8WUM0	NUP133	P24941	CDK2	T684	P680S	680	Missense	distal	-4	no	10.580	10.935	EPSD	COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	Q8WUM0	NUP133	P24941	CDK2	S740	N747S	747	Missense	distal	7	no	8.777	8.718	EPSD	COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	Q8WUM0	NUP133	P24941	CDK2	S740	M735I	735	Missense	distal	-5	no	8.777	8.709	EPSD	COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	Q8WUM0	NUP133	P24941	CDK2	S740	R746I	746	Missense	distal	6	no	8.777	8.793	EPSD	COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	P46013	MKI67	P24941	CDK2	S152	Q156K	156	Missense	distal	4	no	8.241	8.581	EPSD	COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	P46013	MKI67	P24941	CDK2	S235	N229D	229	Missense	distal	-6	no	13.170	13.169	EPSD	COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	P46013	MKI67	P24941	CDK2	S235	Y241H	241	Missense	distal	6	no	13.170	13.173	EPSD	COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	P46013	MKI67	P24941	CDK2	S296	G300V	300	Missense	distal	4	no	7.855	8.202	EPSD	COSMIC	8.148	Gain
CMGC_CDK_CDK2_CDK2_ST	P46013	MKI67	P24941	CDK2	S308	A307P	307	Missense	proximal	-1	no	13.943	14.213	EPSD	COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	P46013	MKI67	P24941	CDK2	S308	H301Y	301	Missense	distal	-7	no	13.943	13.946	EPSD	COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	P46013	MKI67	P24941	CDK2	T328	S330N	330	Missense	proximal	2	no	17.767	17.630	EPSD	COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	P46013	MKI67	P24941	CDK2	T347	T347N	347	Missense	central	0	yes	9.044	0.000	EPSD	COSMIC	8.148	Loss
CMGC_CDK_CDK2_CDK2_ST	P46013	MKI67	P24941	CDK2	S357	N356H	356	Missense	proximal	-1	no	15.647	15.840	PhosphoSitePlus	COSMIC;GDSC;CCLE	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	P46013	MKI67	P24941	CDK2	T391	G386A	386	Missense	distal	-5	no	16.142	16.087	EPSD	COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	P46013	MKI67	P24941	CDK2	T391	T389S	389	Missense	proximal	-2	no	16.142	15.524	EPSD	COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	P46013	MKI67	P24941	CDK2	T391	G386S	386	Missense	distal	-5	no	16.142	16.018	EPSD	COSMIC;GDSC;CCLE	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	P46013	MKI67	P24941	CDK2	T401	E406G	406	Missense	distal	5	no	17.455	17.502	EPSD	COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	P46013	MKI67	P24941	CDK2	T401	E406K	406	Missense	distal	5	no	17.455	17.322	EPSD	COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	P46013	MKI67	P24941	CDK2	T401	P402T	402	Missense	proximal	1	no	17.455	7.498	EPSD	COSMIC	8.148	Loss
CMGC_CDK_CDK2_CDK2_ST	P46013	MKI67	P24941	CDK2	T525	A532D	532	Missense	distal	7	no	17.005	17.307	EPSD	COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	P46013	MKI67	P24941	CDK2	T525	R529S	529	Missense	distal	4	no	17.005	17.138	EPSD	COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	P46013	MKI67	P24941	CDK2	T525	P523L	523	Missense	proximal	-2	no	17.005	16.780	EPSD	COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	P46013	MKI67	P24941	CDK2	T543	R536I	536	Missense	distal	-7	no	11.508	11.359	EPSD	COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	P46013	MKI67	P24941	CDK2	S579	V577I	577	Missense	proximal	-2	no	12.199	12.695	EPSD	COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	P46013	MKI67	P24941	CDK2	S584	V577I	577	Missense	distal	-7	no	16.862	17.037	EPSD	COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	P46013	MKI67	P24941	CDK2	T588	R595H	595	Missense	distal	7	no	12.402	12.044	EPSD	COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	P46013	MKI67	P24941	CDK2	S648	S651L	651	Missense	distal	3	no	8.961	8.543	EPSD	COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	P46013	MKI67	P24941	CDK2	S648	E652K	652	Missense	distal	4	no	8.961	9.346	EPSD	COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	P46013	MKI67	P24941	CDK2	T694	T694M	694	Missense	central	0	yes	15.027	0.000	EPSD	COSMIC	8.148	Loss
CMGC_CDK_CDK2_CDK2_ST	P46013	MKI67	P24941	CDK2	S713	H710R	710	Missense	distal	-3	no	15.083	15.126	EPSD	COSMIC;GDSC;CCLE	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	P46013	MKI67	P24941	CDK2	S713	T708A	708	Missense	distal	-5	no	15.083	15.109	EPSD	COSMIC;GDSC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	P46013	MKI67	P24941	CDK2	S713	P714S	714	Missense	proximal	1	no	15.083	3.817	EPSD	COSMIC	8.148	Loss
CMGC_CDK_CDK2_CDK2_ST	P46013	MKI67	P24941	CDK2	S713	G709C	709	Missense	distal	-4	no	15.083	14.649	EPSD	COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	P46013	MKI67	P24941	CDK2	S713	G720W	720	Missense	distal	7	no	15.083	15.302	EPSD	COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	P46013	MKI67	P24941	CDK2	S713	G709S	709	Missense	distal	-4	no	15.083	15.756	EPSD	COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	P46013	MKI67	P24941	CDK2	T761	P767L	767	Missense	distal	6	no	15.206	15.207	EPSD	COSMIC;GDSC;CCLE	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	P46013	MKI67	P24941	CDK2	T761	P762T	762	Missense	proximal	1	no	15.206	5.249	EPSD	COSMIC	8.148	Loss
CMGC_CDK_CDK2_CDK2_ST	P46013	MKI67	P24941	CDK2	S827	R832W	832	Missense	distal	5	no	12.858	13.024	EPSD	COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	P46013	MKI67	P24941	CDK2	S827	D822V	822	Missense	distal	-5	no	12.858	12.831	EPSD	COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	P46013	MKI67	P24941	CDK2	S827	S825C	825	Missense	proximal	-2	no	12.858	12.447	EPSD	COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	P46013	MKI67	P24941	CDK2	S827	C834F	834	Missense	distal	7	no	12.858	12.918	EPSD	COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	P46013	MKI67	P24941	CDK2	S827	D822Y	822	Missense	distal	-5	no	12.858	12.824	EPSD	COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	P46013	MKI67	P24941	CDK2	T844	T844M	844	Missense	central	0	yes	12.936	0.000	EPSD	COSMIC	8.148	Loss
CMGC_CDK_CDK2_CDK2_ST	P46013	MKI67	P24941	CDK2	T844	K843I	843	Missense	proximal	-1	no	12.936	13.019	EPSD	COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	P46013	MKI67	P24941	CDK2	T1017	P1012L	1012	Missense	distal	-5	no	14.787	14.799	EPSD	COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	P46013	MKI67	P24941	CDK2	T1017	P1014Q	1014	Missense	distal	-3	no	14.787	14.845	EPSD	COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	P46013	MKI67	P24941	CDK2	T1017	P1012S	1012	Missense	distal	-5	no	14.787	14.743	EPSD	COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	P46013	MKI67	P24941	CDK2	T1019	P1012L	1012	Missense	distal	-7	no	9.528	9.533	EPSD	COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	P46013	MKI67	P24941	CDK2	T1019	P1012S	1012	Missense	distal	-7	no	9.528	9.348	EPSD	COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	P46013	MKI67	P24941	CDK2	S1071	R1066T	1066	Missense	distal	-5	no	12.202	12.154	EPSD	COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	P46013	MKI67	P24941	CDK2	S1071	F1068L	1068	Missense	distal	-3	no	12.202	11.944	EPSD	COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	P46013	MKI67	P24941	CDK2	S1071	T1067A	1067	Missense	distal	-4	no	12.202	11.977	EPSD	COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	P46013	MKI67	P24941	CDK2	T1083	R1081S	1081	Missense	proximal	-2	no	10.265	10.849	EPSD	COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	P46013	MKI67	P24941	CDK2	T1083	M1085I	1085	Missense	proximal	2	no	10.265	10.031	EPSD	COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	P46013	MKI67	P24941	CDK2	T1091	Q1097E	1097	Missense	distal	6	no	13.129	13.121	EPSD	COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	P46013	MKI67	P24941	CDK2	T1091	M1085I	1085	Missense	distal	-6	no	13.129	13.124	EPSD	COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	P46013	MKI67	P24941	CDK2	T1091	E1095Q	1095	Missense	distal	4	no	13.129	13.174	EPSD	COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	P46013	MKI67	P24941	CDK2	T1111	F1109L	1109	Missense	proximal	-2	no	12.959	13.848	EPSD	COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	P46013	MKI67	P24941	CDK2	T1111	E1116K	1116	Missense	distal	5	no	12.959	12.826	EPSD	COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	P46013	MKI67	P24941	CDK2	T1120	T1120I	1120	Missense	central	0	yes	9.578	0.000	EPSD	COSMIC	8.148	Loss
CMGC_CDK_CDK2_CDK2_ST	P46013	MKI67	P24941	CDK2	T1120	E1116K	1116	Missense	distal	-4	no	9.578	9.266	EPSD	COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	P46013	MKI67	P24941	CDK2	T1139	K1144E	1144	Missense	distal	5	no	16.279	16.413	EPSD	COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	P46013	MKI67	P24941	CDK2	T1139	P1140Q	1140	Missense	proximal	1	no	16.279	8.368	EPSD	COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	P46013	MKI67	P24941	CDK2	T1167	L1166P	1166	Missense	proximal	-1	no	13.741	13.920	EPSD	COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	P46013	MKI67	P24941	CDK2	T1167	G1171W	1171	Missense	distal	4	no	13.741	13.381	EPSD	COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	P46013	MKI67	P24941	CDK2	T1176	G1171W	1171	Missense	distal	-5	no	11.890	11.944	EPSD	COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	P46013	MKI67	P24941	CDK2	T1176	D1183N	1183	Missense	distal	7	no	11.890	11.110	EPSD	COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	P46013	MKI67	P24941	CDK2	T1193	F1190C	1190	Missense	distal	-3	no	11.331	11.247	EPSD	COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	P46013	MKI67	P24941	CDK2	T1213	L1211V	1211	Missense	proximal	-2	no	13.927	13.501	EPSD	COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	P46013	MKI67	P24941	CDK2	T1213	R1209T	1209	Missense	distal	-4	no	13.927	14.336	EPSD	COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	P46013	MKI67	P24941	CDK2	T1213	K1217E	1217	Missense	distal	4	no	13.927	13.542	EPSD	COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	P46013	MKI67	P24941	CDK2	T1213	A1220G	1220	Missense	distal	7	no	13.927	14.212	EPSD	COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	P46013	MKI67	P24941	CDK2	T1213	G1206V	1206	Missense	distal	-7	no	13.927	13.622	EPSD	COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	P46013	MKI67	P24941	CDK2	T1233	G1226V	1226	Missense	distal	-7	no	13.147	12.842	EPSD	COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	P46013	MKI67	P24941	CDK2	S1253	T1247I	1247	Missense	distal	-6	no	13.686	13.688	EPSD	COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	P46013	MKI67	P24941	CDK2	S1253	S1256P	1256	Missense	distal	3	no	13.686	13.651	EPSD	COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	P46013	MKI67	P24941	CDK2	S1253	D1252N	1252	Missense	proximal	-1	no	13.686	12.856	EPSD	COSMIC;GDSC;CCLE	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	P46013	MKI67	P24941	CDK2	T1261	S1256P	1256	Missense	distal	-5	no	14.931	14.975	EPSD	COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	P46013	MKI67	P24941	CDK2	T1261	P1262Q	1262	Missense	proximal	1	no	14.931	7.019	EPSD	COSMIC	8.148	Loss
CMGC_CDK_CDK2_CDK2_ST	P46013	MKI67	P24941	CDK2	T1261	P1262L	1262	Missense	proximal	1	no	14.931	5.110	EPSD	COSMIC	8.148	Loss
CMGC_CDK_CDK2_CDK2_ST	P46013	MKI67	P24941	CDK2	T1298	T1298M	1298	Missense	central	0	yes	8.539	0.000	EPSD	COSMIC;GDSC	8.148	Loss
CMGC_CDK_CDK2_CDK2_ST	P46013	MKI67	P24941	CDK2	T1298	P1301L	1301	Missense	distal	3	no	8.539	8.155	EPSD	COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	P46013	MKI67	P24941	CDK2	T1298	E1305Q	1305	Missense	distal	7	no	8.539	8.340	EPSD	COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	P46013	MKI67	P24941	CDK2	T1315	G1314V	1314	Missense	proximal	-1	no	13.896	12.804	EPSD	COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	P46013	MKI67	P24941	CDK2	T1327	P1333L	1333	Missense	distal	6	no	8.606	8.608	EPSD	COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	P46013	MKI67	P24941	CDK2	T1335	E1338Q	1338	Missense	distal	3	no	13.492	12.845	EPSD	COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	P46013	MKI67	P24941	CDK2	T1335	P1333L	1333	Missense	proximal	-2	no	13.492	13.267	EPSD	COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	P46013	MKI67	P24941	CDK2	T1335	T1335A	1335	Missense	central	0	yes	13.492	0.000	EPSD	COSMIC	8.148	Loss
CMGC_CDK_CDK2_CDK2_ST	P46013	MKI67	P24941	CDK2	T1347	L1343Q	1343	Missense	distal	-4	no	8.734	8.574	EPSD	COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	P46013	MKI67	P24941	CDK2	T1347	Q1354K	1354	Missense	distal	7	no	8.734	8.603	EPSD	COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	P46013	MKI67	P24941	CDK2	T1355	A1362S	1362	Missense	distal	7	no	13.034	12.497	EPSD	COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	P46013	MKI67	P24941	CDK2	T1355	P1356L	1356	Missense	proximal	1	no	13.034	3.213	EPSD	COSMIC	8.148	Loss
CMGC_CDK_CDK2_CDK2_ST	P46013	MKI67	P24941	CDK2	T1355	Q1354K	1354	Missense	proximal	-1	no	13.034	13.241	EPSD	COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	P46013	MKI67	P24941	CDK2	S1376	P1372S	1372	Missense	distal	-4	no	12.972	13.326	EPSD	COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	P46013	MKI67	P24941	CDK2	S1376	S1376F	1376	Missense	central	0	yes	12.972	0.000	EPSD	COSMIC	8.148	Loss
CMGC_CDK_CDK2_CDK2_ST	P46013	MKI67	P24941	CDK2	T1383	S1376F	1376	Missense	distal	-7	no	14.098	14.650	EPSD	COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	P46013	MKI67	P24941	CDK2	T1393	V1400L	1400	Missense	distal	7	no	13.919	13.691	EPSD	COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	P46013	MKI67	P24941	CDK2	T1418	H1419P	1419	Missense	proximal	1	no	7.130	13.889	EPSD	COSMIC	8.148	Gain
CMGC_CDK_CDK2_CDK2_ST	P46013	MKI67	P24941	CDK2	T1449	P1444S	1444	Missense	distal	-5	no	8.370	8.325	EPSD	COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	P46013	MKI67	P24941	CDK2	T1449	A1445T	1445	Missense	distal	-4	no	8.370	8.595	EPSD	COSMIC;GDSC;CCLE	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	P46013	MKI67	P24941	CDK2	T1485	T1480I	1480	Missense	distal	-5	no	8.583	8.624	EPSD	COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	P46013	MKI67	P24941	CDK2	T1503	P1498L	1498	Missense	distal	-5	no	14.340	14.352	EPSD	COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	P46013	MKI67	P24941	CDK2	T1503	P1509T	1509	Missense	distal	6	no	14.340	14.348	EPSD	COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	P46013	MKI67	P24941	CDK2	T1531	R1530Q	1530	Missense	proximal	-1	no	12.626	11.747	EPSD	COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	P46013	MKI67	P24941	CDK2	T1557	V1559M	1559	Missense	proximal	2	no	11.079	11.168	EPSD	COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	P46013	MKI67	P24941	CDK2	T1569	N1567I	1567	Missense	proximal	-2	no	7.755	8.944	EPSD	COSMIC	8.148	Gain
CMGC_CDK_CDK2_CDK2_ST	P46013	MKI67	P24941	CDK2	T1577	R1574Q	1574	Missense	distal	-3	no	13.129	12.998	EPSD	COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	P46013	MKI67	P24941	CDK2	T1577	L1575P	1575	Missense	proximal	-2	no	13.129	13.353	EPSD	COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	P46013	MKI67	P24941	CDK2	T1577	K1572M	1572	Missense	distal	-5	no	13.129	13.233	EPSD	COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	P46013	MKI67	P24941	CDK2	T1660	E1658K	1658	Missense	proximal	-2	no	7.646	8.247	EPSD	COSMIC	8.148	Gain
CMGC_CDK_CDK2_CDK2_ST	P46013	MKI67	P24941	CDK2	S1679	S1679C	1679	Missense	central	0	yes	10.457	0.000	EPSD	COSMIC	8.148	Loss
CMGC_CDK_CDK2_CDK2_ST	P46013	MKI67	P24941	CDK2	S1679	F1676L	1676	Missense	distal	-3	no	10.457	10.199	EPSD	COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	P46013	MKI67	P24941	CDK2	S1679	S1679F	1679	Missense	central	0	yes	10.457	0.000	EPSD	COSMIC	8.148	Loss
CMGC_CDK_CDK2_CDK2_ST	P46013	MKI67	P24941	CDK2	S1679	S1672I	1672	Missense	distal	-7	no	10.457	10.831	EPSD	COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	P46013	MKI67	P24941	CDK2	S1679	Q1682K	1682	Missense	distal	3	no	10.457	13.189	EPSD	COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	P46013	MKI67	P24941	CDK2	T1691	S1693I	1693	Missense	proximal	2	no	10.345	10.256	EPSD	COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	P46013	MKI67	P24941	CDK2	T1691	A1688V	1688	Missense	distal	-3	no	10.345	10.546	EPSD	COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	P46013	MKI67	P24941	CDK2	T1699	K1701N	1701	Missense	proximal	2	no	13.662	13.732	EPSD	COSMIC;GDSC;CCLE	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	P46013	MKI67	P24941	CDK2	T1699	S1693I	1693	Missense	distal	-6	no	13.662	13.665	EPSD	COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	P46013	MKI67	P24941	CDK2	T1719	G1712A	1712	Missense	distal	-7	no	11.953	11.793	EPSD	COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	P46013	MKI67	P24941	CDK2	S1721	M1727I	1727	Missense	distal	6	no	8.531	8.550	EPSD	COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	P46013	MKI67	P24941	CDK2	T1747	T1749R	1749	Missense	proximal	2	no	15.182	15.518	EPSD	COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	P46013	MKI67	P24941	CDK2	T1747	D1746N	1746	Missense	proximal	-1	no	15.182	14.353	EPSD	COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	P46013	MKI67	P24941	CDK2	T1775	A1778V	1778	Missense	distal	3	no	12.877	13.998	EPSD	COSMIC;GDSC;CCLE	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	P46013	MKI67	P24941	CDK2	T1775	Q1774L	1774	Missense	proximal	-1	no	12.877	13.005	EPSD	COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	P46013	MKI67	P24941	CDK2	T1775	F1768L	1768	Missense	distal	-7	no	12.877	12.511	EPSD	COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	P46013	MKI67	P24941	CDK2	T1775	M1782I	1782	Missense	distal	7	no	12.877	12.389	EPSD	COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	P46013	MKI67	P24941	CDK2	T1775	A1770V	1770	Missense	distal	-5	no	12.877	12.883	EPSD	COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	P46013	MKI67	P24941	CDK2	T1784	H1783N	1783	Missense	proximal	-1	no	9.030	8.837	EPSD	COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	P46013	MKI67	P24941	CDK2	T1784	A1778V	1778	Missense	distal	-6	no	9.030	9.033	EPSD	COSMIC;GDSC;CCLE	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	P46013	MKI67	P24941	CDK2	T1784	M1782I	1782	Missense	proximal	-2	no	9.030	10.960	EPSD	COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	P46013	MKI67	P24941	CDK2	T1801	D1794Y	1794	Missense	distal	-7	no	13.763	13.648	EPSD	COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	P46013	MKI67	P24941	CDK2	T1801	N1796T	1796	Missense	distal	-5	no	13.763	13.743	EPSD	COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	P46013	MKI67	P24941	CDK2	T1841	T1848M	1848	Missense	distal	7	no	11.174	12.023	EPSD	COSMIC;GDSC;CCLE	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	P46013	MKI67	P24941	CDK2	T1841	L1838V	1838	Missense	distal	-3	no	11.174	11.388	EPSD	COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	P46013	MKI67	P24941	CDK2	T1849	T1848M	1848	Missense	proximal	-1	no	7.509	8.822	EPSD	COSMIC;GDSC;CCLE	8.148	Gain
CMGC_CDK_CDK2_CDK2_ST	P46013	MKI67	P24941	CDK2	S1861	Q1863L	1863	Missense	proximal	2	no	12.594	12.428	EPSD	COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	P46013	MKI67	P24941	CDK2	S1861	D1868N	1868	Missense	distal	7	no	12.594	11.814	EPSD	COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	P46013	MKI67	P24941	CDK2	S1861	K1860I	1860	Missense	proximal	-1	no	12.594	12.677	EPSD	COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	P46013	MKI67	P24941	CDK2	S1861	P1862S	1862	Missense	proximal	1	no	12.594	1.328	EPSD	COSMIC	8.148	Loss
CMGC_CDK_CDK2_CDK2_ST	P46013	MKI67	P24941	CDK2	T1869	R1876Q	1876	Missense	distal	7	no	14.825	14.181	EPSD	COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	P46013	MKI67	P24941	CDK2	T1869	T1871S	1871	Missense	proximal	2	no	14.825	15.069	EPSD	COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	P46013	MKI67	P24941	CDK2	T1869	Q1863L	1863	Missense	distal	-6	no	14.825	14.822	EPSD	COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	P46013	MKI67	P24941	CDK2	T1869	D1868N	1868	Missense	proximal	-1	no	14.825	13.996	EPSD	COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	P46013	MKI67	P24941	CDK2	T1869	P1870L	1870	Missense	proximal	1	no	14.825	5.004	EPSD	COSMIC	8.148	Loss
CMGC_CDK_CDK2_CDK2_ST	P46013	MKI67	P24941	CDK2	T1869	P1862S	1862	Missense	distal	-7	no	14.825	14.645	EPSD	COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	P46013	MKI67	P24941	CDK2	T1897	M1904I	1904	Missense	distal	7	no	12.392	11.904	EPSD	COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	P46013	MKI67	P24941	CDK2	T1897	L1896Q	1896	Missense	proximal	-1	no	12.392	12.264	EPSD	COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	P46013	MKI67	P24941	CDK2	T1906	M1904I	1904	Missense	proximal	-2	no	8.726	10.656	EPSD	COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	P46013	MKI67	P24941	CDK2	T1906	G1912C	1912	Missense	distal	6	no	8.726	8.724	EPSD	COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	P46013	MKI67	P24941	CDK2	T1906	A1910E	1910	Missense	distal	4	no	8.726	8.703	EPSD	COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	P46013	MKI67	P24941	CDK2	T1906	T1906M	1906	Missense	central	0	yes	8.726	0.000	EPSD	COSMIC	8.148	Loss
CMGC_CDK_CDK2_CDK2_ST	P46013	MKI67	P24941	CDK2	T1923	T1923I	1923	Missense	central	0	yes	13.948	0.000	EPSD	COSMIC	8.148	Loss
CMGC_CDK_CDK2_CDK2_ST	P46013	MKI67	P24941	CDK2	T1923	V1925A	1925	Missense	proximal	2	no	13.948	13.851	EPSD	COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	P46013	MKI67	P24941	CDK2	T1923	N1918K	1918	Missense	distal	-5	no	13.948	13.932	EPSD	COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	P46013	MKI67	P24941	CDK2	T1943	K1947E	1947	Missense	distal	4	no	13.434	13.049	EPSD	COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	P46013	MKI67	P24941	CDK2	T1943	R1940W	1940	Missense	distal	-3	no	13.434	13.515	EPSD	COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	P46013	MKI67	P24941	CDK2	T1943	A1948T	1948	Missense	distal	5	no	13.434	13.398	EPSD	COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	P46013	MKI67	P24941	CDK2	T1943	K1949R	1949	Missense	distal	6	no	13.434	13.409	EPSD	COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	P46013	MKI67	P24941	CDK2	T1943	A1950T	1950	Missense	distal	7	no	13.434	12.745	EPSD	COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	P46013	MKI67	P24941	CDK2	T1963	H1966L	1966	Missense	distal	3	no	13.140	11.735	EPSD	COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	P46013	MKI67	P24941	CDK2	T1963	G1956S	1956	Missense	distal	-7	no	13.140	12.636	EPSD	COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	P46013	MKI67	P24941	CDK2	T1963	E1968D	1968	Missense	distal	5	no	13.140	13.235	EPSD	COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	P46013	MKI67	P24941	CDK2	T1963	P1964S	1964	Missense	proximal	1	no	13.140	1.874	EPSD	COSMIC	8.148	Loss
CMGC_CDK_CDK2_CDK2_ST	P46013	MKI67	P24941	CDK2	T1972	D1973N	1973	Missense	proximal	1	no	9.746	-22.622	EPSD	COSMIC;GDSC;CCLE	8.148	Loss
CMGC_CDK_CDK2_CDK2_ST	P46013	MKI67	P24941	CDK2	T1972	H1966L	1966	Missense	distal	-6	no	9.746	9.742	EPSD	COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	P46013	MKI67	P24941	CDK2	T1972	E1978K	1978	Missense	distal	6	no	9.746	9.757	EPSD	COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	P46013	MKI67	P24941	CDK2	T1972	E1968D	1968	Missense	distal	-4	no	9.746	10.043	EPSD	COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	P46013	MKI67	P24941	CDK2	S1983	P1988A	1988	Missense	distal	5	no	13.963	13.973	EPSD	COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	P46013	MKI67	P24941	CDK2	S1983	E1978K	1978	Missense	distal	-5	no	13.963	13.928	EPSD	COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	P46013	MKI67	P24941	CDK2	S1983	D1987A	1987	Missense	distal	4	no	13.963	14.068	EPSD	COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	P46013	MKI67	P24941	CDK2	S1983	S1983P	1983	Missense	central	0	yes	13.963	0.000	EPSD	COSMIC	8.148	Loss
CMGC_CDK_CDK2_CDK2_ST	P46013	MKI67	P24941	CDK2	T1991	S1994I	1994	Missense	distal	3	no	14.501	13.799	EPSD	COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	P46013	MKI67	P24941	CDK2	T1991	P1988A	1988	Missense	distal	-3	no	14.501	14.442	EPSD	COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	P46013	MKI67	P24941	CDK2	T1991	T1993R	1993	Missense	proximal	2	no	14.501	14.837	EPSD	COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	P46013	MKI67	P24941	CDK2	T1991	D1987A	1987	Missense	distal	-4	no	14.501	13.915	EPSD	COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	P46013	MKI67	P24941	CDK2	T1991	S1995N	1995	Missense	distal	4	no	14.501	14.467	EPSD	COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	P46013	MKI67	P24941	CDK2	T2065	R2061G	2061	Missense	distal	-4	no	13.372	13.297	EPSD	COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	P46013	MKI67	P24941	CDK2	T2065	E2068K	2068	Missense	distal	3	no	13.372	15.458	EPSD	COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	P46013	MKI67	P24941	CDK2	T2085	Q2084P	2084	Missense	proximal	-1	no	14.490	14.797	EPSD	COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	P46013	MKI67	P24941	CDK2	T2085	F2083S	2083	Missense	proximal	-2	no	14.490	14.952	EPSD	COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	P46013	MKI67	P24941	CDK2	T2085	G2078A	2078	Missense	distal	-7	no	14.490	14.330	EPSD	COSMIC;CCLE	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	P46013	MKI67	P24941	CDK2	T2085	T2085A	2085	Missense	central	0	yes	14.490	0.000	EPSD	COSMIC	8.148	Loss
CMGC_CDK_CDK2_CDK2_ST	P46013	MKI67	P24941	CDK2	S2105	I2101T	2101	Missense	distal	-4	no	14.933	15.250	EPSD	COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	P46013	MKI67	P24941	CDK2	S2105	C2103S	2103	Missense	proximal	-2	no	14.933	15.343	EPSD	COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	P46013	MKI67	P24941	CDK2	S2105	P2107L	2107	Missense	proximal	2	no	14.933	14.826	EPSD	COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	P46013	MKI67	P24941	CDK2	S2105	T2099N	2099	Missense	distal	-6	no	14.933	14.932	EPSD	COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	P46013	MKI67	P24941	CDK2	T2113	R2118S	2118	Missense	distal	5	no	12.560	12.353	EPSD	COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	P46013	MKI67	P24941	CDK2	T2113	S2116N	2116	Missense	distal	3	no	12.560	11.963	EPSD	COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	P46013	MKI67	P24941	CDK2	T2113	T2117A	2117	Missense	distal	4	no	12.560	12.317	EPSD	COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	P46013	MKI67	P24941	CDK2	T2123	R2118S	2118	Missense	distal	-5	no	15.069	14.978	EPSD	COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	P46013	MKI67	P24941	CDK2	T2123	S2116N	2116	Missense	distal	-7	no	15.069	15.168	EPSD	COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	P46013	MKI67	P24941	CDK2	T2123	T2117A	2117	Missense	distal	-6	no	15.069	15.068	EPSD	COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	P46013	MKI67	P24941	CDK2	T2123	T2123I	2123	Missense	central	0	yes	15.069	0.000	EPSD	COSMIC	8.148	Loss
CMGC_CDK_CDK2_CDK2_ST	P46013	MKI67	P24941	CDK2	T2175	A2171V	2171	Missense	distal	-4	no	9.998	10.009	EPSD	COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	P46013	MKI67	P24941	CDK2	T2183	A2188G	2188	Missense	distal	5	no	13.466	13.582	EPSD	COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	P46013	MKI67	P24941	CDK2	T2183	K2185E	2185	Missense	proximal	2	no	13.466	13.703	EPSD	COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	P46013	MKI67	P24941	CDK2	T2183	Q2189K	2189	Missense	distal	6	no	13.466	13.468	EPSD	COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	P46013	MKI67	P24941	CDK2	T2203	P2204A	2204	Missense	proximal	1	no	8.173	-6.230	EPSD	COSMIC	8.148	Loss
CMGC_CDK_CDK2_CDK2_ST	P46013	MKI67	P24941	CDK2	T2203	C2206Y	2206	Missense	distal	3	no	8.173	12.073	EPSD	COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	P46013	MKI67	P24941	CDK2	T2212	T2212N	2212	Missense	central	0	yes	10.202	0.000	EPSD	COSMIC	8.148	Loss
CMGC_CDK_CDK2_CDK2_ST	P46013	MKI67	P24941	CDK2	T2212	H2213D	2213	Missense	proximal	1	no	10.202	8.717	EPSD	COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	P46013	MKI67	P24941	CDK2	T2212	T2211M	2211	Missense	proximal	-1	no	10.202	11.515	EPSD	COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	P46013	MKI67	P24941	CDK2	T2212	C2206Y	2206	Missense	distal	-6	no	10.202	10.197	EPSD	COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	P46013	MKI67	P24941	CDK2	S2223	R2222K	2222	Missense	proximal	-1	no	12.346	11.675	EPSD	COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	P46013	MKI67	P24941	CDK2	T2259	S2252F	2252	Missense	distal	-7	no	14.371	14.923	EPSD	COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	P46013	MKI67	P24941	CDK2	T2259	M2266T	2266	Missense	distal	7	no	14.371	13.522	EPSD	COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	P46013	MKI67	P24941	CDK2	T2259	V2262A	2262	Missense	distal	3	no	14.371	13.251	EPSD	COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	P46013	MKI67	P24941	CDK2	T2259	S2261T	2261	Missense	proximal	2	no	14.371	14.127	EPSD	COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	P46013	MKI67	P24941	CDK2	T2268	M2266T	2266	Missense	proximal	-2	no	11.937	13.988	EPSD	COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	P46013	MKI67	P24941	CDK2	T2268	V2262A	2262	Missense	distal	-6	no	11.937	11.934	EPSD	COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	P46013	MKI67	P24941	CDK2	T2268	T2268K	2268	Missense	central	0	yes	11.937	0.000	EPSD	COSMIC	8.148	Loss
CMGC_CDK_CDK2_CDK2_ST	P46013	MKI67	P24941	CDK2	T2268	G2274C	2274	Missense	distal	6	no	11.937	11.935	EPSD	COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	P46013	MKI67	P24941	CDK2	T2268	S2261T	2261	Missense	distal	-7	no	11.937	12.114	EPSD	COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	P46013	MKI67	P24941	CDK2	T2285	D2278H	2278	Missense	distal	-7	no	11.870	11.752	EPSD	COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	P46013	MKI67	P24941	CDK2	T2285	M2283V	2283	Missense	proximal	-2	no	11.870	13.305	EPSD	COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	P46013	MKI67	P24941	CDK2	T2305	K2309R	2309	Missense	distal	4	no	14.253	13.732	EPSD	COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	P46013	MKI67	P24941	CDK2	T2305	A2310T	2310	Missense	distal	5	no	14.253	14.218	EPSD	COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	P46013	MKI67	P24941	CDK2	T2305	A2312T	2312	Missense	distal	7	no	14.253	13.565	EPSD	COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	P46013	MKI67	P24941	CDK2	T2305	E2308G	2308	Missense	distal	3	no	14.253	13.530	EPSD	COSMIC;CCLE	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	P46013	MKI67	P24941	CDK2	T2305	P2306S	2306	Missense	proximal	1	no	14.253	2.988	EPSD	COSMIC	8.148	Loss
CMGC_CDK_CDK2_CDK2_ST	P46013	MKI67	P24941	CDK2	T2325	E2321D	2321	Missense	distal	-4	no	12.538	12.835	EPSD	COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	P46013	MKI67	P24941	CDK2	T2325	P2331T	2331	Missense	distal	6	no	12.538	12.546	EPSD	COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	P46013	MKI67	P24941	CDK2	T2325	G2327D	2327	Missense	proximal	2	no	12.538	12.418	EPSD	COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	P46013	MKI67	P24941	CDK2	T2333	T2337N	2337	Missense	distal	4	no	8.966	8.663	EPSD	COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	P46013	MKI67	P24941	CDK2	T2333	P2331T	2331	Missense	proximal	-2	no	8.966	8.933	EPSD	COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	P46013	MKI67	P24941	CDK2	T2333	D2334H	2334	Missense	proximal	1	no	8.966	10.451	EPSD	COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	P46013	MKI67	P24941	CDK2	T2333	G2327D	2327	Missense	distal	-6	no	8.966	8.962	EPSD	COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	P46013	MKI67	P24941	CDK2	S2344	T2337N	2337	Missense	distal	-7	no	12.666	12.587	EPSD	COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	P46013	MKI67	P24941	CDK2	S2344	K2343R	2343	Missense	proximal	-1	no	12.666	13.337	EPSD	COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	P46013	MKI67	P24941	CDK2	S2344	D2348H	2348	Missense	distal	4	no	12.666	12.493	EPSD	COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	P46013	MKI67	P24941	CDK2	S2344	P2347S	2347	Missense	distal	3	no	12.666	12.700	EPSD	COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	P46013	MKI67	P24941	CDK2	S2344	A2341V	2341	Missense	distal	-3	no	12.666	12.867	EPSD	COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	P46013	MKI67	P24941	CDK2	T2352	A2354T	2354	Missense	proximal	2	no	16.005	15.803	EPSD	COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	P46013	MKI67	P24941	CDK2	T2352	R2359L	2359	Missense	distal	7	no	16.005	15.546	EPSD	COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	P46013	MKI67	P24941	CDK2	T2352	D2348H	2348	Missense	distal	-4	no	16.005	14.875	EPSD	COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	P46013	MKI67	P24941	CDK2	T2352	P2347S	2347	Missense	distal	-5	no	16.005	15.961	EPSD	COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	P46013	MKI67	P24941	CDK2	T2352	S2355N	2355	Missense	distal	3	no	16.005	15.409	EPSD	COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	P46013	MKI67	P24941	CDK2	T2380	F2373S	2373	Missense	distal	-7	no	12.939	12.388	EPSD	COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	P46013	MKI67	P24941	CDK2	T2380	L2376I	2376	Missense	distal	-4	no	12.939	12.847	EPSD	COSMIC;GDSC;CCLE	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	P46013	MKI67	P24941	CDK2	T2389	P2390S	2390	Missense	proximal	1	no	11.306	0.040	EPSD	COSMIC;GDSC	8.148	Loss
CMGC_CDK_CDK2_CDK2_ST	P46013	MKI67	P24941	CDK2	T2389	T2389R	2389	Missense	central	0	yes	11.306	0.000	EPSD	COSMIC	8.148	Loss
CMGC_CDK_CDK2_CDK2_ST	P46013	MKI67	P24941	CDK2	T2389	D2388H	2388	Missense	proximal	-1	no	11.306	10.669	EPSD	COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	P46013	MKI67	P24941	CDK2	S2395	P2390S	2390	Missense	distal	-5	no	9.592	9.548	EPSD	COSMIC;GDSC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	P46013	MKI67	P24941	CDK2	S2395	T2389R	2389	Missense	distal	-6	no	9.592	9.594	EPSD	COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	P46013	MKI67	P24941	CDK2	S2395	D2388H	2388	Missense	distal	-7	no	9.592	9.474	EPSD	COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	P46013	MKI67	P24941	CDK2	S2395	N2401I	2401	Missense	distal	6	no	9.592	9.588	EPSD	COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	P46013	MKI67	P24941	CDK2	T2406	N2401I	2401	Missense	distal	-5	no	12.686	12.706	EPSD	COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	P46013	MKI67	P24941	CDK2	T2426	P2427T	2427	Missense	proximal	1	no	12.768	2.811	EPSD	COSMIC	8.148	Loss
CMGC_CDK_CDK2_CDK2_ST	P46013	MKI67	P24941	CDK2	T2426	A2433V	2433	Missense	distal	7	no	12.768	12.642	EPSD	COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	P46013	MKI67	P24941	CDK2	T2455	K2458N	2458	Missense	distal	3	no	9.096	5.826	EPSD	COSMIC	8.148	Loss
CMGC_CDK_CDK2_CDK2_ST	P46013	MKI67	P24941	CDK2	S2466	S2471L	2471	Missense	distal	5	no	13.789	13.930	EPSD	COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	P46013	MKI67	P24941	CDK2	S2528	A2524V	2524	Missense	distal	-4	no	12.355	12.366	EPSD	COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	P46013	MKI67	P24941	CDK2	S2528	E2527D	2527	Missense	proximal	-1	no	12.355	12.326	EPSD	COSMIC;GDSC;CCLE	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	P46013	MKI67	P24941	CDK2	T2540	T2540N	2540	Missense	central	0	yes	8.151	0.000	EPSD	COSMIC	8.148	Loss
CMGC_CDK_CDK2_CDK2_ST	P46013	MKI67	P24941	CDK2	S2588	P2585S	2585	Missense	distal	-3	no	14.167	14.262	EPSD	COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	P46013	MKI67	P24941	CDK2	S2588	P2585H	2585	Missense	distal	-3	no	14.167	14.313	EPSD	COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	P46013	MKI67	P24941	CDK2	S2588	D2595Y	2595	Missense	distal	7	no	14.167	13.750	EPSD	COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	P46013	MKI67	P24941	CDK2	S2708	A2701V	2701	Missense	distal	-7	no	15.143	14.998	EPSD	COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	P46013	MKI67	P24941	CDK2	S2719	T2720P	2720	Missense	proximal	1	no	3.099	13.056	EPSD	COSMIC	8.148	Gain
CMGC_CDK_CDK2_CDK2_ST	P46013	MKI67	P24941	CDK2	T2773	P2774L	2774	Missense	proximal	1	no	13.534	3.713	EPSD	COSMIC;GDSC	8.148	Loss
CMGC_CDK_CDK2_CDK2_ST	P46013	MKI67	P24941	CDK2	T2773	S2769F	2769	Missense	distal	-4	no	13.534	12.572	EPSD	COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	P46013	MKI67	P24941	CDK2	T2781	P2774L	2774	Missense	distal	-7	no	9.210	9.215	EPSD	COSMIC;GDSC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	P46013	MKI67	P24941	CDK2	T2781	S2783R	2783	Missense	proximal	2	no	9.210	9.302	EPSD	COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	P46013	MKI67	P24941	CDK2	T2781	R2786Q	2786	Missense	distal	5	no	9.210	9.063	EPSD	COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	P46013	MKI67	P24941	CDK2	T2816	E2813K	2813	Missense	distal	-3	no	9.032	8.817	EPSD	COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	P46013	MKI67	P24941	CDK2	T2816	D2818N	2818	Missense	proximal	2	no	9.032	8.965	EPSD	COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	P46013	MKI67	P24941	CDK2	S2828	S2828L	2828	Missense	central	0	yes	11.483	0.000	EPSD	COSMIC	8.148	Loss
CMGC_CDK_CDK2_CDK2_ST	P46013	MKI67	P24941	CDK2	S2828	A2835T	2835	Missense	distal	7	no	11.483	10.794	EPSD	COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	P46013	MKI67	P24941	CDK2	S2828	E2832D	2832	Missense	distal	4	no	11.483	11.401	EPSD	COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	P46013	MKI67	P24941	CDK2	S2828	P2824S	2824	Missense	distal	-4	no	11.483	11.837	EPSD	COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	P46013	MKI67	P24941	CDK2	S2828	T2834I	2834	Missense	distal	6	no	11.483	11.475	EPSD	COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	P46013	MKI67	P24941	CDK2	S2828	P2824H	2824	Missense	distal	-4	no	11.483	10.879	EPSD	COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	P46013	MKI67	P24941	CDK2	T2927	T2931A	2931	Missense	distal	4	no	14.719	14.476	EPSD	COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	P46013	MKI67	P24941	CDK2	T2927	S2920N	2920	Missense	distal	-7	no	14.719	14.817	EPSD	COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	P46013	MKI67	P24941	CDK2	T2927	H2930Y	2930	Missense	distal	3	no	14.719	12.951	EPSD	COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	P46013	MKI67	P24941	CDK2	T2949	L2956V	2956	Missense	distal	7	no	12.157	12.385	EPSD	COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	P46013	MKI67	P24941	CDK2	T3007	R3013L	3013	Missense	distal	6	no	9.482	9.500	EPSD	COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	P46013	MKI67	P24941	CDK2	T3007	C3014S	3014	Missense	distal	7	no	9.482	8.689	EPSD	COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	P46013	MKI67	P24941	CDK2	T3007	R3011S	3011	Missense	distal	4	no	9.482	9.616	EPSD	COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	P46013	MKI67	P24941	CDK2	T3007	G3001S	3001	Missense	distal	-6	no	9.482	9.479	EPSD	COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	P46013	MKI67	P24941	CDK2	T3007	G3000D	3000	Missense	distal	-7	no	9.482	9.399	EPSD	COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	P46013	MKI67	P24941	CDK2	T3007	R3013G	3013	Missense	distal	6	no	9.482	9.487	EPSD	COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	P46013	MKI67	P24941	CDK2	S3128	M3125V	3125	Missense	distal	-3	no	12.515	12.290	EPSD	COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	P46013	MKI67	P24941	CDK2	S3128	P3124L	3124	Missense	distal	-4	no	12.515	12.457	EPSD	COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	P46013	MKI67	P24941	CDK2	S3249	D3252N	3252	Missense	distal	3	no	7.248	8.499	EPSD	COSMIC	8.148	Gain
CMGC_CDK_CDK2_CDK2_ST	Q9NS91	RAD18	P24941	CDK2	S99	S103T	103	Missense	distal	4	no	17.114	17.384	PhosphoSitePlus	COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	Q9NS91	RAD18	P24941	CDK2	S103	S107F	107	Missense	distal	4	no	12.281	12.085	EPSD	COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	Q9NS91	RAD18	P24941	CDK2	S158	P165R	165	Missense	distal	7	no	16.223	16.713	EPSD	COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	Q9NS91	RAD18	P24941	CDK2	S158	K151I	151	Missense	distal	-7	no	16.223	16.465	EPSD	COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	Q9NS91	RAD18	P24941	CDK2	S164	P165R	165	Missense	proximal	1	no	14.922	5.124	EPSD	COSMIC	8.148	Loss
CMGC_CDK_CDK2_CDK2_ST	Q9NS91	RAD18	P24941	CDK2	S380	E382K	382	Missense	proximal	2	no	8.840	8.603	EPSD	COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	Q9NS91	RAD18	P24941	CDK2	S409	L413M	413	Missense	distal	4	no	17.115	16.582	EPSD	COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	Q9NS91	RAD18	P24941	CDK2	S471	L465V	465	Missense	distal	-6	no	15.137	15.138	EPSD	COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	Q9NS91	RAD18	P24941	CDK2	S471	R476S	476	Missense	distal	5	no	15.137	14.929	EPSD	COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	P26358	DNMT1	P24941	CDK2	S115	R118H	118	Missense	distal	3	no	8.525	7.829	EPSD	COSMIC	8.148	Loss
CMGC_CDK_CDK2_CDK2_ST	P26358	DNMT1	P24941	CDK2	S115	E108Q	108	Missense	distal	-7	no	8.525	8.392	EPSD	COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	P26358	DNMT1	P24941	CDK2	S115	G110R	110	Missense	distal	-5	no	8.525	8.493	EPSD	COSMIC;CCLE	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	P26358	DNMT1	P24941	CDK2	S115	R118L	118	Missense	distal	3	no	8.525	6.423	EPSD	COSMIC	8.148	Loss
CMGC_CDK_CDK2_CDK2_ST	P26358	DNMT1	P24941	CDK2	S127	P128T	128	Missense	proximal	1	no	14.636	4.679	EPSD	COSMIC;GDSC	8.148	Loss
CMGC_CDK_CDK2_CDK2_ST	P26358	DNMT1	P24941	CDK2	S127	S133F	133	Missense	distal	6	no	14.636	14.617	EPSD	COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	P26358	DNMT1	P24941	CDK2	S127	P129L	129	Missense	proximal	2	no	14.636	14.529	EPSD	COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	P26358	DNMT1	P24941	CDK2	S127	L132P	132	Missense	distal	5	no	14.636	14.596	EPSD	COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	P26358	DNMT1	P24941	CDK2	S127	D124C	124	Missense	distal	-3	no	14.636	14.674	EPSD	COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	P26358	DNMT1	P24941	CDK2	T137	S133F	133	Missense	distal	-4	no	16.872	15.910	EPSD	COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	P26358	DNMT1	P24941	CDK2	T137	R140K	140	Missense	distal	3	no	16.872	17.861	EPSD	COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	P26358	DNMT1	P24941	CDK2	T137	R136C	136	Missense	proximal	-1	no	16.872	16.175	EPSD	COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	P26358	DNMT1	P24941	CDK2	T137	L132P	132	Missense	distal	-5	no	16.872	16.861	EPSD	COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	P26358	DNMT1	P24941	CDK2	T137	D144N	144	Missense	distal	7	no	16.872	16.092	EPSD	COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	P26358	DNMT1	P24941	CDK2	S152	S154C	154	Missense	proximal	2	no	14.567	14.646	EPSD	COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	P26358	DNMT1	P24941	CDK2	S154	S161G	161	Missense	distal	7	no	13.641	14.463	PhosphoSitePlus	COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	P26358	DNMT1	P24941	CDK2	S154	S154C	154	Missense	central	0	yes	13.641	0.000	PhosphoSitePlus	COSMIC	8.148	Loss
CMGC_CDK_CDK2_CDK2_ST	P26358	DNMT1	P24941	CDK2	S227	T229M	229	Missense	proximal	2	no	9.594	9.983	EPSD	COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	P26358	DNMT1	P24941	CDK2	S227	S227A	227	Missense	central	0	yes	9.594	0.000	EPSD	COSMIC	8.148	Loss
CMGC_CDK_CDK2_CDK2_ST	P26358	DNMT1	P24941	CDK2	S227	R230C	230	Missense	distal	3	no	9.594	3.230	EPSD	COSMIC	8.148	Loss
CMGC_CDK_CDK2_CDK2_ST	P26358	DNMT1	P24941	CDK2	S227	R230H	230	Missense	distal	3	no	9.594	8.898	EPSD	COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	P26358	DNMT1	P24941	CDK2	S227	S227L	227	Missense	central	0	yes	9.594	0.000	EPSD	COSMIC	8.148	Loss
CMGC_CDK_CDK2_CDK2_ST	P26358	DNMT1	P24941	CDK2	S227	G228E	228	Missense	proximal	1	no	9.594	7.741	EPSD	COSMIC	8.148	Loss
CMGC_CDK_CDK2_CDK2_ST	P26358	DNMT1	P24941	CDK2	S227	E220Q	220	Missense	distal	-7	no	9.594	9.461	EPSD	COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	P26358	DNMT1	P24941	CDK2	S227	R224K	224	Missense	distal	-3	no	9.594	9.365	EPSD	COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	P26358	DNMT1	P24941	CDK2	T229	R230H	230	Missense	proximal	1	no	6.848	9.888	EPSD	COSMIC	8.148	Gain
CMGC_CDK_CDK2_CDK2_ST	P26358	DNMT1	P24941	CDK2	S247	P252L	252	Missense	distal	5	no	9.931	9.971	EPSD	COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	P26358	DNMT1	P24941	CDK2	S247	R246Q	246	Missense	proximal	-1	no	9.931	9.053	EPSD	COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	P26358	DNMT1	P24941	CDK2	S247	P254H	254	Missense	distal	7	no	9.931	10.062	EPSD	COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	P26358	DNMT1	P24941	CDK2	S247	R246C	246	Missense	proximal	-1	no	9.931	9.233	EPSD	COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	P26358	DNMT1	P24941	CDK2	S247	R246H	246	Missense	proximal	-1	no	9.931	9.479	EPSD	COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	P26358	DNMT1	P24941	CDK2	T253	P252L	252	Missense	proximal	-1	no	14.340	14.161	EPSD	COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	P26358	DNMT1	P24941	CDK2	T253	R246Q	246	Missense	distal	-7	no	14.340	13.954	EPSD	COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	P26358	DNMT1	P24941	CDK2	T253	P254H	254	Missense	proximal	1	no	14.340	7.582	EPSD	COSMIC	8.148	Loss
CMGC_CDK_CDK2_CDK2_ST	P26358	DNMT1	P24941	CDK2	T253	R246C	246	Missense	distal	-7	no	14.340	14.267	EPSD	COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	P26358	DNMT1	P24941	CDK2	T253	R246H	246	Missense	distal	-7	no	14.340	14.120	EPSD	COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	P26358	DNMT1	P24941	CDK2	S312	I311M	311	Missense	proximal	-1	no	9.111	10.177	EPSD	COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	P26358	DNMT1	P24941	CDK2	S312	Q310R	310	Missense	proximal	-2	no	9.111	8.442	EPSD	COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	P26358	DNMT1	P24941	CDK2	S312	I311V	311	Missense	proximal	-1	no	9.111	9.084	EPSD	COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	P26358	DNMT1	P24941	CDK2	S312	S312F	312	Missense	central	0	yes	9.111	0.000	EPSD	COSMIC	8.148	Loss
CMGC_CDK_CDK2_CDK2_ST	P26358	DNMT1	P24941	CDK2	S312	E305G	305	Missense	distal	-7	no	9.111	9.345	EPSD	COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	P26358	DNMT1	P24941	CDK2	S312	V307L	307	Missense	distal	-5	no	9.111	9.091	EPSD	COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	P26358	DNMT1	P24941	CDK2	S312	V307G	307	Missense	distal	-5	no	9.111	9.159	EPSD	COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	P26358	DNMT1	P24941	CDK2	T328	R325H	325	Missense	distal	-3	no	13.716	13.673	EPSD	COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	P26358	DNMT1	P24941	CDK2	T328	R325L	325	Missense	distal	-3	no	13.716	13.456	EPSD	COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	P26358	DNMT1	P24941	CDK2	T328	P332L	332	Missense	distal	4	no	13.716	13.828	EPSD	COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	P26358	DNMT1	P24941	CDK2	T328	E321G	321	Missense	distal	-7	no	13.716	13.950	EPSD	COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	P26358	DNMT1	P24941	CDK2	S394	A401S	401	Missense	distal	7	no	9.026	8.489	EPSD	COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	P26358	DNMT1	P24941	CDK2	S394	I388M	388	Missense	distal	-6	no	9.026	9.031	EPSD	COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	P26358	DNMT1	P24941	CDK2	S714	P710S	710	Missense	distal	-4	no	16.063	16.418	EPSD	COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	P26358	DNMT1	P24941	CDK2	S714	M712T	712	Missense	proximal	-2	no	16.063	18.114	EPSD	COSMIC;GDSC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	P26358	DNMT1	P24941	CDK2	S714	M712L	712	Missense	proximal	-2	no	16.063	17.924	EPSD	COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	P26358	DNMT1	P24941	CDK2	S878	P879S	879	Missense	proximal	1	no	17.043	5.777	EPSD	COSMIC;CCLE	8.148	Loss
CMGC_CDK_CDK2_CDK2_ST	P26358	DNMT1	P24941	CDK2	S878	E877K	877	Missense	proximal	-1	no	17.043	16.158	EPSD	COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	P26358	DNMT1	P24941	CDK2	S878	T882I	882	Missense	distal	4	no	17.043	16.731	EPSD	COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	P26358	DNMT1	P24941	CDK2	S954	R958C	958	Missense	distal	4	no	15.310	14.684	EPSD	COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	P26358	DNMT1	P24941	CDK2	S954	P955L	955	Missense	proximal	1	no	15.310	5.490	EPSD	COSMIC	8.148	Loss
CMGC_CDK_CDK2_CDK2_ST	P26358	DNMT1	P24941	CDK2	S954	K961N	961	Missense	distal	7	no	15.310	15.503	EPSD	COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	P26358	DNMT1	P24941	CDK2	S954	R960Q	960	Missense	distal	6	no	15.310	15.332	EPSD	COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	P26358	DNMT1	P24941	CDK2	S954	K951R	951	Missense	distal	-3	no	15.310	15.540	EPSD	COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	P26358	DNMT1	P24941	CDK2	S954	R958H	958	Missense	distal	4	no	15.310	15.193	EPSD	COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	P26358	DNMT1	P24941	CDK2	S954	P959S	959	Missense	distal	5	no	15.310	15.209	EPSD	COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	P26358	DNMT1	P24941	CDK2	S954	T947M	947	Missense	distal	-7	no	15.310	15.814	EPSD	COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	P26358	DNMT1	P24941	CDK2	S954	I950M	950	Missense	distal	-4	no	15.310	14.713	EPSD	COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	P26358	DNMT1	P24941	CDK2	S1105	N1101K	1101	Missense	distal	-4	no	16.630	16.411	EPSD	COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	P26358	DNMT1	P24941	CDK2	S1105	D1098V	1098	Missense	distal	-7	no	16.630	16.408	EPSD	COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	P26358	DNMT1	P24941	CDK2	S1105	R1104C	1104	Missense	proximal	-1	no	16.630	15.932	EPSD	COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	P26358	DNMT1	P24941	CDK2	S1105	P1106L	1106	Missense	proximal	1	no	16.630	6.809	EPSD	COSMIC	8.148	Loss
CMGC_CDK_CDK2_CDK2_ST	P26358	DNMT1	P24941	CDK2	S1122	Q1123P	1123	Missense	proximal	1	no	3.036	10.948	EPSD	COSMIC	8.148	Gain
CMGC_CDK_CDK2_CDK2_ST	P26358	DNMT1	P24941	CDK2	S1128	E1129G	1129	Missense	proximal	1	no	6.989	8.842	EPSD	COSMIC	8.148	Gain
CMGC_CDK_CDK2_CDK2_ST	P26358	DNMT1	P24941	CDK2	S1206	R1207H	1207	Missense	proximal	1	no	7.631	10.670	EPSD	COSMIC	8.148	Gain
CMGC_CDK_CDK2_CDK2_ST	Q2NL82	TSR1	P24941	CDK2	T490	E487D	487	Missense	distal	-3	no	15.273	15.164	PhosphoSitePlus	COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	Q2NL82	TSR1	P24941	CDK2	T577	V570A	570	Missense	distal	-7	no	11.959	12.104	EPSD	COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	Q2NL82	TSR1	P24941	CDK2	T577	L579V	579	Missense	proximal	2	no	11.959	12.188	EPSD	COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	P22674	CCNO	P24941	CDK2	T3	P6S	6	Missense	distal	3	no	8.952	8.986	EPSD	COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	P22674	CCNO	P24941	CDK2	S8	P6S	6	Missense	proximal	-2	no	12.426	11.775	EPSD	COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	P22674	CCNO	P24941	CDK2	S8	R15Q	15	Missense	distal	7	no	12.426	11.782	EPSD	COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	P22674	CCNO	P24941	CDK2	S8	A14S	14	Missense	distal	6	no	12.426	12.432	EPSD	COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	P22674	CCNO	P24941	CDK2	S11	G17E	17	Missense	distal	6	no	9.734	9.743	EPSD	COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	P22674	CCNO	P24941	CDK2	S11	P6S	6	Missense	distal	-5	no	9.734	9.690	EPSD	COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	P22674	CCNO	P24941	CDK2	S11	R15Q	15	Missense	distal	4	no	9.734	9.916	EPSD	COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	P22674	CCNO	P24941	CDK2	S11	A14S	14	Missense	distal	3	no	9.734	10.280	EPSD	COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	P22674	CCNO	P24941	CDK2	S81	A87T	87	Missense	distal	6	no	16.985	16.997	PhosphoSitePlus	COSMIC;CCLE	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	P22674	CCNO	P24941	CDK2	S81	A87V	87	Missense	distal	6	no	16.985	16.988	PhosphoSitePlus	COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	Q9P2B4	CTTNBP2NL	P24941	CDK2	S285	E288K	288	Missense	distal	3	no	13.740	15.826	EPSD	COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	Q9P2B4	CTTNBP2NL	P24941	CDK2	S285	E278D	278	Missense	distal	-7	no	13.740	13.891	EPSD	COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	Q9P2B4	CTTNBP2NL	P24941	CDK2	T340	T333I	333	Missense	distal	-7	no	10.277	10.474	EPSD	COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	Q9P2B4	CTTNBP2NL	P24941	CDK2	S430	R436C	436	Missense	distal	6	no	13.445	13.447	EPSD	COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	Q9P2B4	CTTNBP2NL	P24941	CDK2	S430	L423V	423	Missense	distal	-7	no	13.445	13.459	EPSD	COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	Q9P2B4	CTTNBP2NL	P24941	CDK2	S430	S426F	426	Missense	distal	-4	no	13.445	12.482	EPSD	COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	Q9P2B4	CTTNBP2NL	P24941	CDK2	S444	S450T	450	Missense	distal	6	no	13.640	13.646	EPSD	COSMIC;GDSC;CCLE	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	Q9P2B4	CTTNBP2NL	P24941	CDK2	S444	A442S	442	Missense	proximal	-2	no	13.640	12.973	EPSD	COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	Q9P2B4	CTTNBP2NL	P24941	CDK2	S481	L487V	487	Missense	distal	6	no	15.038	15.035	EPSD	COSMIC;GDSC;CCLE	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	Q9P2B4	CTTNBP2NL	P24941	CDK2	S481	S484F	484	Missense	distal	3	no	15.038	14.963	EPSD	COSMIC;GDSC;CCLE	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	Q9P2B4	CTTNBP2NL	P24941	CDK2	S488	L487V	487	Missense	proximal	-1	no	13.683	13.819	EPSD	COSMIC;GDSC;CCLE	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	Q9P2B4	CTTNBP2NL	P24941	CDK2	S488	S484F	484	Missense	distal	-4	no	13.683	12.721	EPSD	COSMIC;GDSC;CCLE	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	Q9P2B4	CTTNBP2NL	P24941	CDK2	S549	R543K	543	Missense	distal	-6	no	13.188	13.186	EPSD	COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	Q9P2B4	CTTNBP2NL	P24941	CDK2	S549	P550F	550	Missense	proximal	1	no	13.188	-1.622	EPSD	COSMIC	8.148	Loss
CMGC_CDK_CDK2_CDK2_ST	Q9P2B4	CTTNBP2NL	P24941	CDK2	S549	T546R	546	Missense	distal	-3	no	13.188	13.416	EPSD	COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	Q9P2B4	CTTNBP2NL	P24941	CDK2	T551	P550F	550	Missense	proximal	-1	no	16.693	17.479	EPSD	COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	Q9P2B4	CTTNBP2NL	P24941	CDK2	T551	T546R	546	Missense	distal	-5	no	16.693	16.742	EPSD	COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	Q9P2B4	CTTNBP2NL	P24941	CDK2	S557	P550F	550	Missense	distal	-7	no	12.412	12.784	EPSD	COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	Q9P2B4	CTTNBP2NL	P24941	CDK2	S557	P564L	564	Missense	distal	7	no	12.412	12.443	EPSD	COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	Q9P2B4	CTTNBP2NL	P24941	CDK2	S560	P564L	564	Missense	distal	4	no	16.512	16.624	EPSD	COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	Q9P2B4	CTTNBP2NL	P24941	CDK2	S563	P564L	564	Missense	proximal	1	no	14.208	4.387	PhosphoSitePlus	COSMIC	8.148	Loss
CMGC_CDK_CDK2_CDK2_ST	Q9P2B4	CTTNBP2NL	P24941	CDK2	S568	P564L	564	Missense	distal	-4	no	12.058	12.000	EPSD	COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	Q9P2B4	CTTNBP2NL	P24941	CDK2	S592	P598L	598	Missense	distal	6	no	13.846	13.848	EPSD	COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	Q9P2B4	CTTNBP2NL	P24941	CDK2	T597	P598L	598	Missense	proximal	1	no	13.582	3.761	EPSD	COSMIC	8.148	Loss
CMGC_CDK_CDK2_CDK2_ST	O75616	ERAL1	P24941	CDK2	S53	R56C	56	Missense	distal	3	no	8.647	2.283	EPSD	COSMIC;GDSC;CCLE	8.148	Loss
CMGC_CDK_CDK2_CDK2_ST	O75616	ERAL1	P24941	CDK2	T168	I172M	172	Missense	distal	4	no	13.521	13.129	EPSD	COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	O75616	ERAL1	P24941	CDK2	S173	I172M	172	Missense	proximal	-1	no	17.645	18.712	PhosphoSitePlus	COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	O75616	ERAL1	P24941	CDK2	S216	R212Q	212	Missense	distal	-4	no	11.150	11.175	EPSD	COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	O75616	ERAL1	P24941	CDK2	S216	L223M	223	Missense	distal	7	no	11.150	11.665	EPSD	COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	P17096	HMGA1	P24941	CDK2	S36	P37S	37	Missense	proximal	1	no	14.045	2.779	PhosphoSitePlus	COSMIC	8.148	Loss
CMGC_CDK_CDK2_CDK2_ST	P17096	HMGA1	P24941	CDK2	T78	T75I	75	Missense	distal	-3	no	15.071	15.130	EPSD	COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	P38398	BRCA1	P24941	CDK2	S72	D67E	67	Missense	distal	-5	no	8.317	8.297	EPSD	COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	P38398	BRCA1	P24941	CDK2	S72	R71G	71	Missense	proximal	-1	no	8.317	8.795	EPSD	COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	P38398	BRCA1	P24941	CDK2	S72	T77M	77	Missense	distal	5	no	8.317	8.650	EPSD	COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	P38398	BRCA1	P24941	CDK2	S72	S76R	76	Missense	distal	4	no	8.317	8.183	EPSD	COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	P38398	BRCA1	P24941	CDK2	S72	R71K	71	Missense	proximal	-1	no	8.317	7.646	EPSD	COSMIC	8.148	Loss
CMGC_CDK_CDK2_CDK2_ST	P38398	BRCA1	P24941	CDK2	S114	D120A	120	Missense	distal	6	no	14.472	14.483	EPSD	COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	P38398	BRCA1	P24941	CDK2	S114	P115L	115	Missense	proximal	1	no	14.472	4.651	EPSD	COSMIC	8.148	Loss
CMGC_CDK_CDK2_CDK2_ST	P38398	BRCA1	P24941	CDK2	S114	F107Y	107	Missense	distal	-7	no	14.472	14.226	EPSD	COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	P38398	BRCA1	P24941	CDK2	S114	N113S	113	Missense	proximal	-1	no	14.472	14.075	EPSD	COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	P38398	BRCA1	P24941	CDK2	S114	E111K	111	Missense	distal	-3	no	14.472	14.257	EPSD	COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	P38398	BRCA1	P24941	CDK2	S114	A108V	108	Missense	distal	-6	no	14.472	14.475	EPSD	COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	P38398	BRCA1	P24941	CDK2	S114	E116K	116	Missense	proximal	2	no	14.472	14.234	EPSD	COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	P38398	BRCA1	P24941	CDK2	S114	P115R	115	Missense	proximal	1	no	14.472	4.674	EPSD	COSMIC	8.148	Loss
CMGC_CDK_CDK2_CDK2_ST	P38398	BRCA1	P24941	CDK2	T208	L204F	204	Missense	distal	-4	no	11.288	10.739	EPSD	COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	P38398	BRCA1	P24941	CDK2	T208	E215K	215	Missense	distal	7	no	11.288	10.957	EPSD	COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	P38398	BRCA1	P24941	CDK2	T208	Q202R	202	Missense	distal	-6	no	11.288	11.287	EPSD	COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	P38398	BRCA1	P24941	CDK2	T208	Q210E	210	Missense	proximal	2	no	11.288	11.325	EPSD	COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	P38398	BRCA1	P24941	CDK2	T208	E203K	203	Missense	distal	-5	no	11.288	11.253	EPSD	COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	P38398	BRCA1	P24941	CDK2	T333	C328Y	328	Missense	distal	-5	no	14.275	14.218	EPSD	COSMIC;GDSC;CCLE	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	P38398	BRCA1	P24941	CDK2	T333	K338I	338	Missense	distal	5	no	14.275	14.422	EPSD	COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	P38398	BRCA1	P24941	CDK2	T333	P334S	334	Missense	proximal	1	no	14.275	3.009	EPSD	COSMIC	8.148	Loss
CMGC_CDK_CDK2_CDK2_ST	P38398	BRCA1	P24941	CDK2	T333	S335N	335	Missense	proximal	2	no	14.275	14.138	EPSD	COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	P38398	BRCA1	P24941	CDK2	T333	R332Q	332	Missense	proximal	-1	no	14.275	13.397	EPSD	COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	P38398	BRCA1	P24941	CDK2	T333	D330N	330	Missense	distal	-3	no	14.275	14.230	EPSD	COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	P38398	BRCA1	P24941	CDK2	T333	R332W	332	Missense	proximal	-1	no	14.275	14.829	EPSD	COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	P38398	BRCA1	P24941	CDK2	T333	R331G	331	Missense	proximal	-2	no	14.275	14.768	EPSD	COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	P38398	BRCA1	P24941	CDK2	T333	S335I	335	Missense	proximal	2	no	14.275	14.185	EPSD	COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	P38398	BRCA1	P24941	CDK2	T333	E337V	337	Missense	distal	4	no	14.275	14.485	EPSD	COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	P38398	BRCA1	P24941	CDK2	T333	T327A	327	Missense	distal	-6	no	14.275	14.274	EPSD	COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	P38398	BRCA1	P24941	CDK2	S510	R506S	506	Missense	distal	-4	no	9.362	9.960	EPSD	COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	P38398	BRCA1	P24941	CDK2	S510	R504C	504	Missense	distal	-6	no	9.362	9.365	EPSD	COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	P38398	BRCA1	P24941	CDK2	S510	S510L	510	Missense	central	0	yes	9.362	0.000	EPSD	COSMIC	8.148	Loss
CMGC_CDK_CDK2_CDK2_ST	P38398	BRCA1	P24941	CDK2	S510	L512F	512	Missense	proximal	2	no	9.362	9.720	EPSD	COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	P38398	BRCA1	P24941	CDK2	S510	R507K	507	Missense	distal	-3	no	9.362	9.133	EPSD	COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	P38398	BRCA1	P24941	CDK2	S510	R507I	507	Missense	distal	-3	no	9.362	9.193	EPSD	COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	P38398	BRCA1	P24941	CDK2	T528	G535R	535	Missense	distal	7	no	13.750	13.570	EPSD	COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	P38398	BRCA1	P24941	CDK2	T528	I532F	532	Missense	distal	4	no	13.750	13.596	EPSD	COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	P38398	BRCA1	P24941	CDK2	S632	N630H	630	Missense	proximal	-2	no	8.616	8.949	EPSD	COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	P38398	BRCA1	P24941	CDK2	S632	P633S	633	Missense	proximal	1	no	8.616	-2.650	EPSD	COSMIC	8.148	Loss
CMGC_CDK_CDK2_CDK2_ST	P38398	BRCA1	P24941	CDK2	S632	P634S	634	Missense	proximal	2	no	8.616	8.682	EPSD	COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	P38398	BRCA1	P24941	CDK2	S632	S628N	628	Missense	distal	-4	no	8.616	8.400	EPSD	COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	P38398	BRCA1	P24941	CDK2	S632	T637N	637	Missense	distal	5	no	8.616	8.744	EPSD	COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	P38398	BRCA1	P24941	CDK2	S632	E638D	638	Missense	distal	6	no	8.616	8.603	EPSD	COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	P38398	BRCA1	P24941	CDK2	S632	C636F	636	Missense	distal	4	no	8.616	9.180	EPSD	COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	P38398	BRCA1	P24941	CDK2	S632	P634R	634	Missense	proximal	2	no	8.616	8.774	EPSD	COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	P38398	BRCA1	P24941	CDK2	S753	M751I	751	Missense	proximal	-2	no	6.723	8.653	EPSD	COSMIC	8.148	Gain
CMGC_CDK_CDK2_CDK2_ST	P38398	BRCA1	P24941	CDK2	S896	Q895R	895	Missense	proximal	-1	no	16.991	17.869	EPSD	COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	P38398	BRCA1	P24941	CDK2	S896	G890W	890	Missense	distal	-6	no	16.991	16.996	EPSD	COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	P38398	BRCA1	P24941	CDK2	S896	G890V	890	Missense	distal	-6	no	16.991	16.990	EPSD	COSMIC;GDSC;CCLE	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	P38398	BRCA1	P24941	CDK2	S896	E902Q	902	Missense	distal	6	no	16.991	16.999	EPSD	COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	P38398	BRCA1	P24941	CDK2	S896	G890R	890	Missense	distal	-6	no	16.991	16.990	EPSD	COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	P38398	BRCA1	P24941	CDK2	S896	K898E	898	Missense	proximal	2	no	16.991	17.228	EPSD	COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	P38398	BRCA1	P24941	CDK2	T967	E962K	962	Missense	distal	-5	no	17.308	17.274	EPSD	COSMIC;GDSC;CCLE	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	P38398	BRCA1	P24941	CDK2	T967	T967I	967	Missense	central	0	yes	17.308	0.000	EPSD	COSMIC	8.148	Loss
CMGC_CDK_CDK2_CDK2_ST	P38398	BRCA1	P24941	CDK2	T967	N969I	969	Missense	proximal	2	no	17.308	17.356	EPSD	COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	P38398	BRCA1	P24941	CDK2	S1009	E1011K	1011	Missense	proximal	2	no	17.412	17.174	EPSD	COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	P38398	BRCA1	P24941	CDK2	S1009	M1008I	1008	Missense	proximal	-1	no	17.412	16.345	EPSD	COSMIC;GDSC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	P38398	BRCA1	P24941	CDK2	S1009	M1014I	1014	Missense	distal	5	no	17.412	17.197	EPSD	COSMIC;GDSC;CCLE	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	P38398	BRCA1	P24941	CDK2	S1009	M1014K	1014	Missense	distal	5	no	17.412	17.050	EPSD	COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	P38398	BRCA1	P24941	CDK2	S1009	N1016I	1016	Missense	distal	7	no	17.412	17.562	EPSD	COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	P38398	BRCA1	P24941	CDK2	S1009	S1009F	1009	Missense	central	0	yes	17.412	0.000	EPSD	COSMIC	8.148	Loss
CMGC_CDK_CDK2_CDK2_ST	P38398	BRCA1	P24941	CDK2	S1009	E1013D	1013	Missense	distal	4	no	17.412	17.330	EPSD	COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	P38398	BRCA1	P24941	CDK2	S1189	K1183R	1183	Missense	distal	-6	no	14.840	14.842	EPSD	COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	P38398	BRCA1	P24941	CDK2	S1189	E1185Q	1185	Missense	distal	-4	no	14.840	14.391	EPSD	COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	P38398	BRCA1	P24941	CDK2	S1189	P1190H	1190	Missense	proximal	1	no	14.840	8.081	EPSD	COSMIC;GDSC;CCLE	8.148	Loss
CMGC_CDK_CDK2_CDK2_ST	P38398	BRCA1	P24941	CDK2	S1189	P1190F	1190	Missense	proximal	1	no	14.840	0.030	EPSD	COSMIC	8.148	Loss
CMGC_CDK_CDK2_CDK2_ST	P38398	BRCA1	P24941	CDK2	S1189	Q1182H	1182	Missense	distal	-7	no	14.840	15.006	EPSD	COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	P38398	BRCA1	P24941	CDK2	S1189	P1192F	1192	Missense	distal	3	no	14.840	14.799	EPSD	COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	P38398	BRCA1	P24941	CDK2	S1189	P1190L	1190	Missense	proximal	1	no	14.840	5.019	EPSD	COSMIC	8.148	Loss
CMGC_CDK_CDK2_CDK2_ST	P38398	BRCA1	P24941	CDK2	S1189	P1192S	1192	Missense	distal	3	no	14.840	14.874	EPSD	COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	P38398	BRCA1	P24941	CDK2	S1189	P1192L	1192	Missense	distal	3	no	14.840	14.456	EPSD	COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	P38398	BRCA1	P24941	CDK2	S1189	R1188K	1188	Missense	proximal	-1	no	14.840	14.169	EPSD	COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	P38398	BRCA1	P24941	CDK2	S1191	E1185Q	1185	Missense	distal	-6	no	13.683	13.684	EPSD	COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	P38398	BRCA1	P24941	CDK2	S1191	P1190H	1190	Missense	proximal	-1	no	13.683	13.802	EPSD	COSMIC;GDSC;CCLE	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	P38398	BRCA1	P24941	CDK2	S1191	P1190F	1190	Missense	proximal	-1	no	13.683	14.469	EPSD	COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	P38398	BRCA1	P24941	CDK2	S1191	P1192F	1192	Missense	proximal	1	no	13.683	-1.127	EPSD	COSMIC	8.148	Loss
CMGC_CDK_CDK2_CDK2_ST	P38398	BRCA1	P24941	CDK2	S1191	P1190L	1190	Missense	proximal	-1	no	13.683	13.504	EPSD	COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	P38398	BRCA1	P24941	CDK2	S1191	P1192S	1192	Missense	proximal	1	no	13.683	2.417	EPSD	COSMIC	8.148	Loss
CMGC_CDK_CDK2_CDK2_ST	P38398	BRCA1	P24941	CDK2	S1191	P1192L	1192	Missense	proximal	1	no	13.683	3.862	EPSD	COSMIC	8.148	Loss
CMGC_CDK_CDK2_CDK2_ST	P38398	BRCA1	P24941	CDK2	S1191	R1188K	1188	Missense	distal	-3	no	13.683	13.454	EPSD	COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	P38398	BRCA1	P24941	CDK2	S1191	H1197Y	1197	Missense	distal	6	no	13.683	13.680	EPSD	COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	P38398	BRCA1	P24941	CDK2	S1211	S1212P	1212	Missense	proximal	1	no	4.661	15.927	EPSD	COSMIC	8.148	Gain
CMGC_CDK_CDK2_CDK2_ST	P38398	BRCA1	P24941	CDK2	S1496	S1497P	1497	Missense	proximal	1	no	1.875	13.141	EPSD	COSMIC	8.148	Gain
CMGC_CDK_CDK2_CDK2_ST	P38398	BRCA1	P24941	CDK2	S1497	P1502L	1502	Missense	distal	5	no	14.361	14.401	PhosphoSitePlus	COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	P38398	BRCA1	P24941	CDK2	S1497	S1499F	1499	Missense	proximal	2	no	14.361	14.545	PhosphoSitePlus	COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	P38398	BRCA1	P24941	CDK2	S1497	E1490Q	1490	Missense	distal	-7	no	14.361	14.228	PhosphoSitePlus	COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	P38398	BRCA1	P24941	CDK2	S1497	S1497P	1497	Missense	central	0	yes	14.361	0.000	PhosphoSitePlus	COSMIC	8.148	Loss
CMGC_CDK_CDK2_CDK2_ST	P38398	BRCA1	P24941	CDK2	S1497	V1493E	1493	Missense	distal	-4	no	14.361	14.640	PhosphoSitePlus	COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	P38398	BRCA1	P24941	CDK2	S1516	L1517P	1517	Missense	proximal	1	no	6.073	15.894	EPSD	COSMIC	8.148	Gain
CMGC_CDK_CDK2_CDK2_ST	P38398	BRCA1	P24941	CDK2	T1561	L1564P	1564	Missense	distal	3	no	13.897	14.280	EPSD	COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	P38398	BRCA1	P24941	CDK2	T1561	L1558I	1558	Missense	distal	-3	no	13.897	13.988	EPSD	COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	P38398	BRCA1	P24941	CDK2	T1561	P1562L	1562	Missense	proximal	1	no	13.897	4.076	EPSD	COSMIC	8.148	Loss
CMGC_CDK_CDK2_CDK2_ST	P38398	BRCA1	P24941	CDK2	T1561	P1562T	1562	Missense	proximal	1	no	13.897	3.940	EPSD	COSMIC	8.148	Loss
CMGC_CDK_CDK2_CDK2_ST	P38398	BRCA1	P24941	CDK2	T1561	I1568S	1568	Missense	distal	7	no	13.897	13.688	EPSD	COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	P38398	BRCA1	P24941	CDK2	T1561	S1566G	1566	Missense	distal	5	no	13.897	14.124	EPSD	COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	P38398	BRCA1	P24941	CDK2	S1566	S1569G	1569	Missense	distal	3	no	8.345	8.210	EPSD	COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	P38398	BRCA1	P24941	CDK2	S1566	L1564P	1564	Missense	proximal	-2	no	8.345	8.569	EPSD	COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	P38398	BRCA1	P24941	CDK2	S1566	P1562L	1562	Missense	distal	-4	no	8.345	8.287	EPSD	COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	P38398	BRCA1	P24941	CDK2	S1566	L1570P	1570	Missense	distal	4	no	8.345	8.233	EPSD	COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	P38398	BRCA1	P24941	CDK2	S1566	P1562T	1562	Missense	distal	-4	no	8.345	8.512	EPSD	COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	P38398	BRCA1	P24941	CDK2	S1566	I1568S	1568	Missense	proximal	2	no	8.345	8.434	EPSD	COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	P38398	BRCA1	P24941	CDK2	S1566	S1566G	1566	Missense	central	0	yes	8.345	0.000	EPSD	COSMIC	8.148	Loss
CMGC_CDK_CDK2_CDK2_ST	P38398	BRCA1	P24941	CDK2	S1566	S1572C	1572	Missense	distal	6	no	8.345	8.330	EPSD	COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	P38398	BRCA1	P24941	CDK2	S1566	S1572T	1572	Missense	distal	6	no	8.345	8.351	EPSD	COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	P38398	BRCA1	P24941	CDK2	S1569	L1570P	1570	Missense	proximal	1	no	3.877	13.698	EPSD	COSMIC	8.148	Gain
CMGC_CDK_CDK2_CDK2_ST	P38398	BRCA1	P24941	CDK2	S1577	D1578H	1578	Missense	proximal	1	no	6.911	8.396	EPSD	COSMIC	8.148	Gain
CMGC_CDK_CDK2_CDK2_ST	P38398	BRCA1	P24941	CDK2	T1597	S1598P	1598	Missense	proximal	1	no	1.232	12.497	EPSD	COSMIC	8.148	Gain
CMGC_CDK_CDK2_CDK2_ST	P38398	BRCA1	P24941	CDK2	S1613	S1613G	1613	Missense	central	0	yes	13.553	0.000	EPSD	COSMIC	8.148	Loss
CMGC_CDK_CDK2_CDK2_ST	P38398	BRCA1	P24941	CDK2	S1613	T1619S	1619	Missense	distal	6	no	13.553	13.547	EPSD	COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	P38398	BRCA1	P24941	CDK2	S1613	A1608T	1608	Missense	distal	-5	no	13.553	13.527	EPSD	COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	P38398	BRCA1	P24941	CDK2	S1613	Q1612H	1612	Missense	proximal	-1	no	13.553	13.980	EPSD	COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	P38398	BRCA1	P24941	CDK2	S1613	A1615V	1615	Missense	proximal	2	no	13.553	13.651	EPSD	COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	P38398	BRCA1	P24941	CDK2	S1613	V1607M	1607	Missense	distal	-6	no	13.553	13.559	EPSD	COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	P38398	BRCA1	P24941	CDK2	S1613	V1607E	1607	Missense	distal	-6	no	13.553	13.554	EPSD	COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	P38398	BRCA1	P24941	CDK2	S1655	P1659Q	1659	Missense	distal	4	no	9.509	9.570	EPSD	COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	P38398	BRCA1	P24941	CDK2	S1655	P1659L	1659	Missense	distal	4	no	9.509	9.621	EPSD	COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	P38398	BRCA1	P24941	CDK2	S1655	M1652I	1652	Missense	distal	-3	no	9.509	9.161	EPSD	COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	P38398	BRCA1	P24941	CDK2	S1655	S1651F	1651	Missense	distal	-4	no	9.509	8.547	EPSD	COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	P38398	BRCA1	P24941	CDK2	S1655	R1649T	1649	Missense	distal	-6	no	9.509	9.507	EPSD	COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	P38398	BRCA1	P24941	CDK2	S1655	V1654E	1654	Missense	proximal	-1	no	9.509	10.337	EPSD	COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	P38398	BRCA1	P24941	CDK2	S1655	V1653A	1653	Missense	proximal	-2	no	9.509	10.175	EPSD	COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	P38398	BRCA1	P24941	CDK2	S1655	R1649K	1649	Missense	distal	-6	no	9.509	9.507	EPSD	COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	P38398	BRCA1	P24941	CDK2	S1655	V1654M	1654	Missense	proximal	-1	no	9.509	10.602	EPSD	COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	P38398	BRCA1	P24941	CDK2	S1655	E1661K	1661	Missense	distal	6	no	9.509	9.520	EPSD	COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	P38398	BRCA1	P24941	CDK2	T1658	P1659Q	1659	Missense	proximal	1	no	13.327	5.415	EPSD	COSMIC	8.148	Loss
CMGC_CDK_CDK2_CDK2_ST	P38398	BRCA1	P24941	CDK2	T1658	P1659L	1659	Missense	proximal	1	no	13.327	3.506	EPSD	COSMIC	8.148	Loss
CMGC_CDK_CDK2_CDK2_ST	P38398	BRCA1	P24941	CDK2	T1658	M1652I	1652	Missense	distal	-6	no	13.327	13.322	EPSD	COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	P38398	BRCA1	P24941	CDK2	T1658	V1665L	1665	Missense	distal	7	no	13.327	13.099	EPSD	COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	P38398	BRCA1	P24941	CDK2	T1658	S1651F	1651	Missense	distal	-7	no	13.327	13.878	EPSD	COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	P38398	BRCA1	P24941	CDK2	T1658	V1654E	1654	Missense	distal	-4	no	13.327	13.605	EPSD	COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	P38398	BRCA1	P24941	CDK2	T1658	M1663V	1663	Missense	distal	5	no	13.327	12.986	EPSD	COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	P38398	BRCA1	P24941	CDK2	T1658	V1653A	1653	Missense	distal	-5	no	13.327	13.321	EPSD	COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	P38398	BRCA1	P24941	CDK2	T1658	V1654M	1654	Missense	distal	-4	no	13.327	12.626	EPSD	COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	P38398	BRCA1	P24941	CDK2	T1658	E1661K	1661	Missense	distal	3	no	13.327	15.412	EPSD	COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	Q9H1E3	NUCKS1	P24941	CDK2	S40	R38Q	38	Missense	proximal	-2	no	13.456	14.125	EPSD	COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	Q9H1E3	NUCKS1	P24941	CDK2	S40	P33S	33	Missense	distal	-7	no	13.456	13.276	EPSD	COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	Q9H1E3	NUCKS1	P24941	CDK2	S61	E59D	59	Missense	proximal	-2	no	8.120	9.101	EPSD	COSMIC	8.148	Gain
CMGC_CDK_CDK2_CDK2_ST	Q9H1E3	NUCKS1	P24941	CDK2	T179	T179M	179	Missense	central	0	yes	10.411	0.000	EPSD	COSMIC	8.148	Loss
CMGC_CDK_CDK2_CDK2_ST	Q9H1E3	NUCKS1	P24941	CDK2	S181	T179M	179	Missense	proximal	-2	no	16.204	14.153	PhosphoSitePlus	COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	Q9H1E3	NUCKS1	P24941	CDK2	T202	P205S	205	Missense	distal	3	no	11.962	11.996	EPSD	COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	Q9H1E3	NUCKS1	P24941	CDK2	T202	P205L	205	Missense	distal	3	no	11.962	11.578	EPSD	COSMIC;CCLE	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	Q9H1E3	NUCKS1	P24941	CDK2	S204	P205S	205	Missense	proximal	1	no	14.862	3.596	EPSD	COSMIC	8.148	Loss
CMGC_CDK_CDK2_CDK2_ST	Q9H1E3	NUCKS1	P24941	CDK2	S204	P205L	205	Missense	proximal	1	no	14.862	5.041	EPSD	COSMIC;CCLE	8.148	Loss
CMGC_CDK_CDK2_CDK2_ST	Q9H1E3	NUCKS1	P24941	CDK2	S214	S221C	221	Missense	distal	7	no	15.974	16.767	EPSD	COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	Q9H1E3	NUCKS1	P24941	CDK2	S214	S214I	214	Missense	central	0	yes	15.974	0.000	EPSD	COSMIC	8.148	Loss
CMGC_CDK_CDK2_CDK2_ST	Q9H1E3	NUCKS1	P24941	CDK2	S214	P215L	215	Missense	proximal	1	no	15.974	6.153	EPSD	COSMIC	8.148	Loss
CMGC_CDK_CDK2_CDK2_ST	Q9H1E3	NUCKS1	P24941	CDK2	S223	S221C	221	Missense	proximal	-2	no	15.342	14.932	EPSD	COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	Q9H1E3	NUCKS1	P24941	CDK2	S223	P224S	224	Missense	proximal	1	no	15.342	4.076	EPSD	COSMIC	8.148	Loss
CMGC_CDK_CDK2_CDK2_ST	Q9H1E3	NUCKS1	P24941	CDK2	S223	P225S	225	Missense	proximal	2	no	15.342	15.409	EPSD	COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	Q9H1E3	NUCKS1	P24941	CDK2	S223	S223R	223	Missense	central	0	yes	15.342	0.000	EPSD	COSMIC	8.148	Loss
CMGC_CDK_CDK2_CDK2_ST	Q9H1E3	NUCKS1	P24941	CDK2	S229	P225S	225	Missense	distal	-4	no	8.143	8.497	EPSD	COSMIC	8.148	Gain
CMGC_CDK_CDK2_CDK2_ST	Q9UQ80	PA2G4	P24941	CDK2	S90	Q96E	96	Missense	distal	6	no	21.060	21.052	EPSD	COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	Q9UQ80	PA2G4	P24941	CDK2	S90	P91H	91	Missense	proximal	1	no	21.060	14.302	EPSD	COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	Q9UQ80	PA2G4	P24941	CDK2	T180	G184S	184	Missense	distal	4	no	13.872	14.005	EPSD	COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	Q9H3D4	TP63	P24941	CDK2	S51	E48K	48	Missense	distal	-3	no	15.306	15.091	EPSD	COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	Q9H3D4	TP63	P24941	CDK2	S51	S51N	51	Missense	central	0	yes	15.306	0.000	EPSD	COSMIC	8.148	Loss
CMGC_CDK_CDK2_CDK2_ST	Q9H3D4	TP63	P24941	CDK2	S51	F55V	55	Missense	distal	4	no	15.306	15.716	EPSD	COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	Q9H3D4	TP63	P24941	CDK2	S51	F55L	55	Missense	distal	4	no	15.306	15.601	EPSD	COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	Q9H3D4	TP63	P24941	CDK2	S51	L50F	50	Missense	proximal	-1	no	15.306	16.271	EPSD	COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	Q9H3D4	TP63	P24941	CDK2	S51	P52L	52	Missense	proximal	1	no	15.306	5.485	EPSD	COSMIC	8.148	Loss
CMGC_CDK_CDK2_CDK2_ST	Q9H3D4	TP63	P24941	CDK2	S51	H57R	57	Missense	distal	6	no	15.306	15.295	EPSD	COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	Q9H3D4	TP63	P24941	CDK2	S160	P161S	161	Missense	proximal	1	no	12.081	0.815	EPSD	COSMIC	8.148	Loss
CMGC_CDK_CDK2_CDK2_ST	Q9H3D4	TP63	P24941	CDK2	S160	L159F	159	Missense	proximal	-1	no	12.081	13.046	EPSD	COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	Q9H3D4	TP63	P24941	CDK2	S160	S160C	160	Missense	central	0	yes	12.081	0.000	EPSD	COSMIC	8.148	Loss
CMGC_CDK_CDK2_CDK2_ST	Q9H3D4	TP63	P24941	CDK2	S160	S154C	154	Missense	distal	-6	no	12.081	12.087	EPSD	COSMIC;CCLE	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	Q9H3D4	TP63	P24941	CDK2	S160	S153I	153	Missense	distal	-7	no	12.081	12.455	EPSD	COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	Q9H3D4	TP63	P24941	CDK2	S160	P166H	166	Missense	distal	6	no	12.081	12.076	EPSD	COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	Q9H3D4	TP63	P24941	CDK2	S160	P161L	161	Missense	proximal	1	no	12.081	2.260	EPSD	COSMIC	8.148	Loss
CMGC_CDK_CDK2_CDK2_ST	Q9H3D4	TP63	P24941	CDK2	S162	T169N	169	Missense	distal	7	no	10.982	11.193	EPSD	COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	Q9H3D4	TP63	P24941	CDK2	S162	P161S	161	Missense	proximal	-1	no	10.982	10.511	EPSD	COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	Q9H3D4	TP63	P24941	CDK2	S162	L159F	159	Missense	distal	-3	no	10.982	11.240	EPSD	COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	Q9H3D4	TP63	P24941	CDK2	S162	S160C	160	Missense	proximal	-2	no	10.982	10.572	EPSD	COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	Q9H3D4	TP63	P24941	CDK2	S162	T169I	169	Missense	distal	7	no	10.982	11.343	EPSD	COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	Q9H3D4	TP63	P24941	CDK2	S162	P166H	166	Missense	distal	4	no	10.982	10.745	EPSD	COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	Q9H3D4	TP63	P24941	CDK2	S162	N168S	168	Missense	distal	6	no	10.982	10.980	EPSD	COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	Q9H3D4	TP63	P24941	CDK2	S162	P161L	161	Missense	proximal	-1	no	10.982	10.803	EPSD	COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	Q9H3D4	TP63	P24941	CDK2	S395	K392E	392	Missense	distal	-3	no	10.892	11.107	EPSD	COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	Q9H3D4	TP63	P24941	CDK2	S395	S395F	395	Missense	central	0	yes	10.892	0.000	EPSD	COSMIC;GDSC	8.148	Loss
CMGC_CDK_CDK2_CDK2_ST	Q9H3D4	TP63	P24941	CDK2	S455	S462L	462	Missense	distal	7	no	13.585	13.768	EPSD	COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	Q9H3D4	TP63	P24941	CDK2	S455	S462A	462	Missense	distal	7	no	13.585	14.122	EPSD	COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	Q9H3D4	TP63	P24941	CDK2	S455	Q454H	454	Missense	proximal	-1	no	13.585	14.012	EPSD	COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	Q9H3D4	TP63	P24941	CDK2	S455	Q454R	454	Missense	proximal	-1	no	13.585	14.463	EPSD	COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	Q9H3D4	TP63	P24941	CDK2	S455	Q450R	450	Missense	distal	-5	no	13.585	13.632	EPSD	COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	Q9H3D4	TP63	P24941	CDK2	S455	Q450H	450	Missense	distal	-5	no	13.585	13.632	EPSD	COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	Q9H3D4	TP63	P24941	CDK2	S455	S457G	457	Missense	proximal	2	no	13.585	13.636	EPSD	COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	Q9H3D4	TP63	P24941	CDK2	S463	S462L	462	Missense	proximal	-1	no	11.144	11.436	EPSD	COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	Q9H3D4	TP63	P24941	CDK2	S463	S462A	462	Missense	proximal	-1	no	11.144	11.345	EPSD	COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	Q9H3D4	TP63	P24941	CDK2	S463	N467K	467	Missense	distal	4	no	11.144	11.566	EPSD	COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	Q9H3D4	TP63	P24941	CDK2	S463	N470S	470	Missense	distal	7	no	11.144	11.086	EPSD	COSMIC;GDSC;CCLE	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	Q9H3D4	TP63	P24941	CDK2	S463	S457G	457	Missense	distal	-6	no	11.144	11.147	EPSD	COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	Q9H3D4	TP63	P24941	CDK2	T491	P492H	492	Missense	proximal	1	no	13.063	6.304	PhosphoSitePlus	COSMIC	8.148	Loss
CMGC_CDK_CDK2_CDK2_ST	Q9H3D4	TP63	P24941	CDK2	T491	P484H	484	Missense	distal	-7	no	13.063	13.186	PhosphoSitePlus	COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	Q9H3D4	TP63	P24941	CDK2	T491	T494A	494	Missense	distal	3	no	13.063	12.665	PhosphoSitePlus	COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	Q9H3D4	TP63	P24941	CDK2	T491	I495M	495	Missense	distal	4	no	13.063	12.670	PhosphoSitePlus	COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	Q9H3D4	TP63	P24941	CDK2	T491	P492T	492	Missense	proximal	1	no	13.063	3.105	PhosphoSitePlus	COSMIC	8.148	Loss
CMGC_CDK_CDK2_CDK2_ST	Q9H3D4	TP63	P24941	CDK2	T491	D497N	497	Missense	distal	6	no	13.063	13.082	PhosphoSitePlus	COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	Q9H3D4	TP63	P24941	CDK2	T491	L490R	490	Missense	proximal	-1	no	13.063	13.813	PhosphoSitePlus	COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	Q9H3D4	TP63	P24941	CDK2	T491	P496H	496	Missense	distal	5	no	13.063	13.140	PhosphoSitePlus	COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	Q9H3D4	TP63	P24941	CDK2	S612	R618W	618	Missense	distal	6	no	13.702	13.695	EPSD	COSMIC;GDSC;CCLE	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	Q9H3D4	TP63	P24941	CDK2	S612	R605Q	605	Missense	distal	-7	no	13.702	13.316	EPSD	COSMIC;GDSC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	Q9H3D4	TP63	P24941	CDK2	S612	R618Q	618	Missense	distal	6	no	13.702	13.724	EPSD	COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	Q9H3D4	TP63	P24941	CDK2	S612	R605W	605	Missense	distal	-7	no	13.702	13.873	EPSD	COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	Q9H3D4	TP63	P24941	CDK2	S612	S612F	612	Missense	central	0	yes	13.702	0.000	EPSD	COSMIC	8.148	Loss
CMGC_CDK_CDK2_CDK2_ST	Q9H3D4	TP63	P24941	CDK2	S612	P613L	613	Missense	proximal	1	no	13.702	3.881	EPSD	COSMIC	8.148	Loss
CMGC_CDK_CDK2_CDK2_ST	Q9H3D4	TP63	P24941	CDK2	S612	H615D	615	Missense	distal	3	no	13.702	10.866	EPSD	COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	Q9H3D4	TP63	P24941	CDK2	S612	P613T	613	Missense	proximal	1	no	13.702	3.745	EPSD	COSMIC	8.148	Loss
CMGC_CDK_CDK2_CDK2_ST	Q9H3D4	TP63	P24941	CDK2	S612	H608Q	608	Missense	distal	-4	no	13.702	14.088	EPSD	COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	Q9H3D4	TP63	P24941	CDK2	T619	V626F	626	Missense	distal	7	no	14.501	14.944	EPSD	COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	Q9H3D4	TP63	P24941	CDK2	T619	R618W	618	Missense	proximal	-1	no	14.501	15.055	EPSD	COSMIC;GDSC;CCLE	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	Q9H3D4	TP63	P24941	CDK2	T619	R618Q	618	Missense	proximal	-1	no	14.501	13.623	EPSD	COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	Q9H3D4	TP63	P24941	CDK2	T619	S622I	622	Missense	distal	3	no	14.501	13.799	EPSD	COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	Q9H3D4	TP63	P24941	CDK2	T619	S612F	612	Missense	distal	-7	no	14.501	15.052	EPSD	COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	Q9H3D4	TP63	P24941	CDK2	T619	H615D	615	Missense	distal	-4	no	14.501	15.632	EPSD	COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	Q9H3D4	TP63	P24941	CDK2	T619	P613T	613	Missense	distal	-6	no	14.501	14.500	EPSD	COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	O75152	ZC3H11A	P24941	CDK2	S108	T104A	104	Missense	distal	-4	no	14.733	14.508	EPSD	COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	O75152	ZC3H11A	P24941	CDK2	S149	S149R	149	Missense	central	0	yes	15.255	0.000	EPSD	COSMIC	8.148	Loss
CMGC_CDK_CDK2_CDK2_ST	O75152	ZC3H11A	P24941	CDK2	S149	P150H	150	Missense	proximal	1	no	15.255	8.497	EPSD	COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	O75152	ZC3H11A	P24941	CDK2	T179	L182P	182	Missense	distal	3	no	11.614	11.998	EPSD	COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	O75152	ZC3H11A	P24941	CDK2	T181	L182P	182	Missense	proximal	1	no	4.865	14.686	EPSD	COSMIC	8.148	Gain
CMGC_CDK_CDK2_CDK2_ST	O75152	ZC3H11A	P24941	CDK2	T185	L182P	182	Missense	distal	-3	no	13.808	13.879	EPSD	COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	O75152	ZC3H11A	P24941	CDK2	T321	K323T	323	Missense	proximal	2	no	17.644	17.608	PhosphoSitePlus	COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	O75152	ZC3H11A	P24941	CDK2	T502	R506K	506	Missense	distal	4	no	11.820	12.342	EPSD	COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	O75152	ZC3H11A	P24941	CDK2	S663	L666S	666	Missense	distal	3	no	11.007	11.424	EPSD	COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	O75152	ZC3H11A	P24941	CDK2	S781	G783S	783	Missense	proximal	2	no	10.570	10.519	EPSD	COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	Q8IXJ6	SIRT2	P24941	CDK2	S25	G29E	29	Missense	distal	4	no	9.646	9.783	EPSD	COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	Q8IXJ6	SIRT2	P24941	CDK2	S25	E28D	28	Missense	distal	3	no	9.646	7.210	EPSD	COSMIC	8.148	Loss
CMGC_CDK_CDK2_CDK2_ST	Q8IXJ6	SIRT2	P24941	CDK2	S193	F190V	190	Missense	distal	-3	no	10.259	10.215	EPSD	COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	Q8IXJ6	SIRT2	P24941	CDK2	T280	S274F	274	Missense	distal	-6	no	14.094	14.099	EPSD	COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	Q8IXJ6	SIRT2	P24941	CDK2	T280	S279F	279	Missense	proximal	-1	no	14.094	15.351	EPSD	COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	Q8IXJ6	SIRT2	P24941	CDK2	T280	R282H	282	Missense	proximal	2	no	14.094	14.013	EPSD	COSMIC;GDSC;CCLE	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	Q8IXJ6	SIRT2	P24941	CDK2	T280	R282C	282	Missense	proximal	2	no	14.094	14.081	EPSD	COSMIC;GDSC;CCLE	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	Q8IXJ6	SIRT2	P24941	CDK2	T280	K275N	275	Missense	distal	-5	no	14.094	14.111	EPSD	COSMIC;GDSC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	Q8IXJ6	SIRT2	P24941	CDK2	S368	P373S	373	Missense	distal	5	no	15.904	15.803	PhosphoSitePlus;EPSD	COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	Q8IXJ6	SIRT2	P24941	CDK2	S368	P374S	374	Missense	distal	6	no	15.904	15.905	PhosphoSitePlus;EPSD	COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	Q8IXJ6	SIRT2	P24941	CDK2	S372	P373S	373	Missense	proximal	1	no	14.855	3.589	EPSD	COSMIC	8.148	Loss
CMGC_CDK_CDK2_CDK2_ST	Q8IXJ6	SIRT2	P24941	CDK2	S372	P374S	374	Missense	proximal	2	no	14.855	14.921	EPSD	COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	P55795	HNRNPH2	P24941	CDK2	S63	E64G	64	Missense	proximal	1	no	8.590	10.444	EPSD	COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	P55795	HNRNPH2	P24941	CDK2	S104	D106E	106	Missense	proximal	2	no	14.520	14.620	PhosphoSitePlus	COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	P55795	HNRNPH2	P24941	CDK2	S257	D258H	258	Missense	proximal	1	no	7.848	9.333	EPSD	COSMIC	8.148	Gain
CMGC_CDK_CDK2_CDK2_ST	P55795	HNRNPH2	P24941	CDK2	S269	L264H	264	Missense	distal	-5	no	8.137	8.173	EPSD	COSMIC	8.148	Gain
CMGC_CDK_CDK2_CDK2_ST	P55795	HNRNPH2	P24941	CDK2	S272	M271V	271	Missense	proximal	-1	no	8.567	7.474	EPSD	COSMIC	8.148	Loss
CMGC_CDK_CDK2_CDK2_ST	P55795	HNRNPH2	P24941	CDK2	S310	I305T	305	Missense	distal	-5	no	14.756	14.715	EPSD	COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	P55795	HNRNPH2	P24941	CDK2	S310	R316S	316	Missense	distal	6	no	14.756	14.773	EPSD	COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	Q9P270	SLAIN2	P24941	CDK2	S81	S88I	88	Missense	distal	7	no	10.180	10.389	EPSD	COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	Q9P270	SLAIN2	P24941	CDK2	T140	S147R	147	Missense	distal	7	no	12.481	13.122	EPSD	COSMIC;CCLE	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	Q9P270	SLAIN2	P24941	CDK2	S147	S147R	147	Missense	central	0	yes	14.293	0.000	EPSD	COSMIC;CCLE	8.148	Loss
CMGC_CDK_CDK2_CDK2_ST	Q9P270	SLAIN2	P24941	CDK2	S198	N203S	203	Missense	distal	5	no	13.561	13.357	EPSD	COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	Q9P270	SLAIN2	P24941	CDK2	S201	N203S	203	Missense	proximal	2	no	14.209	14.346	EPSD	COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	Q9P270	SLAIN2	P24941	CDK2	S214	P215A	215	Missense	proximal	1	no	15.242	0.839	EPSD	COSMIC	8.148	Loss
CMGC_CDK_CDK2_CDK2_ST	Q9P270	SLAIN2	P24941	CDK2	S214	S217L	217	Missense	distal	3	no	15.242	14.825	EPSD	COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	Q9P270	SLAIN2	P24941	CDK2	S247	Q249R	249	Missense	proximal	2	no	15.152	15.251	EPSD	COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	Q9P270	SLAIN2	P24941	CDK2	S247	S247I	247	Missense	central	0	yes	15.152	0.000	EPSD	COSMIC	8.148	Loss
CMGC_CDK_CDK2_CDK2_ST	Q9P270	SLAIN2	P24941	CDK2	S247	D241G	241	Missense	distal	-6	no	15.152	15.156	EPSD	COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	Q9P270	SLAIN2	P24941	CDK2	S247	I252V	252	Missense	distal	5	no	15.152	15.026	EPSD	COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	Q9P270	SLAIN2	P24941	CDK2	S247	D241Y	241	Missense	distal	-6	no	15.152	15.153	EPSD	COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	Q9P270	SLAIN2	P24941	CDK2	S315	G312R	312	Missense	distal	-3	no	9.324	9.410	EPSD	COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	Q9P270	SLAIN2	P24941	CDK2	S315	A321V	321	Missense	distal	6	no	9.324	9.327	EPSD	COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	Q9P270	SLAIN2	P24941	CDK2	S315	G312V	312	Missense	distal	-3	no	9.324	9.364	EPSD	COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	Q9P270	SLAIN2	P24941	CDK2	S315	A321S	321	Missense	distal	6	no	9.324	9.330	EPSD	COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	Q9P270	SLAIN2	P24941	CDK2	S315	T313A	313	Missense	proximal	-2	no	9.324	9.374	EPSD	COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	Q9P270	SLAIN2	P24941	CDK2	S343	P350T	350	Missense	distal	7	no	14.013	13.709	EPSD	COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	Q9P270	SLAIN2	P24941	CDK2	S343	R341M	341	Missense	proximal	-2	no	14.013	13.164	EPSD	COSMIC;CCLE	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	Q9P270	SLAIN2	P24941	CDK2	S343	R347H	347	Missense	distal	4	no	14.013	13.895	EPSD	COSMIC;GDSC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	Q9P270	SLAIN2	P24941	CDK2	S343	A338V	338	Missense	distal	-5	no	14.013	14.019	EPSD	COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	Q9P270	SLAIN2	P24941	CDK2	S345	P350T	350	Missense	distal	5	no	11.858	11.832	EPSD	COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	Q9P270	SLAIN2	P24941	CDK2	S345	R341M	341	Missense	distal	-4	no	11.858	11.352	EPSD	COSMIC;CCLE	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	Q9P270	SLAIN2	P24941	CDK2	S345	R347H	347	Missense	proximal	2	no	11.858	11.777	EPSD	COSMIC;GDSC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	Q9P270	SLAIN2	P24941	CDK2	S345	A338V	338	Missense	distal	-7	no	11.858	11.713	EPSD	COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	Q9P270	SLAIN2	P24941	CDK2	S349	P350T	350	Missense	proximal	1	no	14.807	4.850	EPSD	COSMIC	8.148	Loss
CMGC_CDK_CDK2_CDK2_ST	Q9P270	SLAIN2	P24941	CDK2	S349	R347H	347	Missense	proximal	-2	no	14.807	15.033	EPSD	COSMIC;GDSC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	Q9P270	SLAIN2	P24941	CDK2	S349	S353L	353	Missense	distal	4	no	14.807	14.906	EPSD	COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	Q9P270	SLAIN2	P24941	CDK2	S353	P350T	350	Missense	distal	-3	no	11.669	11.629	EPSD	COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	Q9P270	SLAIN2	P24941	CDK2	S353	R347H	347	Missense	distal	-6	no	11.669	11.670	EPSD	COSMIC;GDSC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	Q9P270	SLAIN2	P24941	CDK2	S353	R359K	359	Missense	distal	6	no	11.669	11.693	EPSD	COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	Q9P270	SLAIN2	P24941	CDK2	S353	S353L	353	Missense	central	0	yes	11.669	0.000	EPSD	COSMIC	8.148	Loss
CMGC_CDK_CDK2_CDK2_ST	Q9P270	SLAIN2	P24941	CDK2	S357	P350T	350	Missense	distal	-7	no	12.354	12.351	EPSD	COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	Q9P270	SLAIN2	P24941	CDK2	S357	R359K	359	Missense	proximal	2	no	12.354	12.054	EPSD	COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	Q9P270	SLAIN2	P24941	CDK2	S357	S353L	353	Missense	distal	-4	no	12.354	11.941	EPSD	COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	Q9P270	SLAIN2	P24941	CDK2	S361	R365L	365	Missense	distal	4	no	13.096	13.328	EPSD	COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	Q9P270	SLAIN2	P24941	CDK2	S361	R365Q	365	Missense	distal	4	no	13.096	13.277	EPSD	COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	Q9P270	SLAIN2	P24941	CDK2	S361	R359K	359	Missense	proximal	-2	no	13.096	13.817	EPSD	COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	Q9P270	SLAIN2	P24941	CDK2	S361	P367S	367	Missense	distal	6	no	13.096	13.097	EPSD	COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	Q9P270	SLAIN2	P24941	CDK2	S361	P367L	367	Missense	distal	6	no	13.096	13.097	EPSD	COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	Q9P270	SLAIN2	P24941	CDK2	S366	R365L	365	Missense	proximal	-1	no	17.857	17.107	EPSD	COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	Q9P270	SLAIN2	P24941	CDK2	S366	R365Q	365	Missense	proximal	-1	no	17.857	16.979	EPSD	COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	Q9P270	SLAIN2	P24941	CDK2	S366	R359K	359	Missense	distal	-7	no	17.857	17.466	EPSD	COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	Q9P270	SLAIN2	P24941	CDK2	S366	P367S	367	Missense	proximal	1	no	17.857	6.591	EPSD	COSMIC	8.148	Loss
CMGC_CDK_CDK2_CDK2_ST	Q9P270	SLAIN2	P24941	CDK2	S366	P367L	367	Missense	proximal	1	no	17.857	8.036	EPSD	COSMIC	8.148	Loss
CMGC_CDK_CDK2_CDK2_ST	Q9P270	SLAIN2	P24941	CDK2	S456	F460L	460	Missense	distal	4	no	15.167	15.461	EPSD	COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	Q9P270	SLAIN2	P24941	CDK2	S456	P449H	449	Missense	distal	-7	no	15.167	15.290	EPSD	COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	Q9P270	SLAIN2	P24941	CDK2	S456	P463A	463	Missense	distal	7	no	15.167	15.552	EPSD	COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	Q9P270	SLAIN2	P24941	CDK2	S456	R461C	461	Missense	distal	5	no	15.167	15.294	EPSD	COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	Q9P270	SLAIN2	P24941	CDK2	S462	F460L	460	Missense	proximal	-2	no	13.727	14.616	EPSD	COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	Q9P270	SLAIN2	P24941	CDK2	S462	P463A	463	Missense	proximal	1	no	13.727	-0.676	EPSD	COSMIC	8.148	Loss
CMGC_CDK_CDK2_CDK2_ST	Q9P270	SLAIN2	P24941	CDK2	S462	R461C	461	Missense	proximal	-1	no	13.727	13.030	EPSD	COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	Q9P270	SLAIN2	P24941	CDK2	S467	F460L	460	Missense	distal	-7	no	13.708	13.342	EPSD	COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	Q9P270	SLAIN2	P24941	CDK2	S467	P463A	463	Missense	distal	-4	no	13.708	13.649	EPSD	COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	Q9P270	SLAIN2	P24941	CDK2	S467	R472Q	472	Missense	distal	5	no	13.708	13.561	EPSD	COSMIC;GDSC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	Q9P270	SLAIN2	P24941	CDK2	S467	R461C	461	Missense	distal	-6	no	13.708	13.711	EPSD	COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	Q13309	SKP2	P24941	CDK2	S64	L70R	70	Missense	distal	6	no	15.360	15.342	PhosphoSitePlus	COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	Q13309	SKP2	P24941	CDK2	S179	P173Q	173	Missense	distal	-6	no	17.503	17.506	EPSD	COSMIC;CCLE	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	Q13309	SKP2	P24941	CDK2	S179	S179L	179	Missense	central	0	yes	17.503	0.000	EPSD	COSMIC	8.148	Loss
CMGC_CDK_CDK2_CDK2_ST	P04637	TP53	P24941	CDK2	S15	T18K	18	Missense	distal	3	no	7.251	10.073	EPSD	COSMIC	8.148	Gain
CMGC_CDK_CDK2_CDK2_ST	P04637	TP53	P24941	CDK2	S15	T18R	18	Missense	distal	3	no	7.251	9.084	EPSD	COSMIC	8.148	Gain
CMGC_CDK_CDK2_CDK2_ST	P04637	TP53	P24941	CDK2	S33	M40I	40	Missense	distal	7	no	15.549	15.061	EPSD	COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	P04637	TP53	P24941	CDK2	S33	V31I	31	Missense	proximal	-2	no	15.549	16.045	EPSD	COSMIC;GDSC;CCLE	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	P04637	TP53	P24941	CDK2	S33	P36L	36	Missense	distal	3	no	15.549	15.166	EPSD	COSMIC;GDSC;CCLE	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	P04637	TP53	P24941	CDK2	S33	L35F	35	Missense	proximal	2	no	15.549	15.907	EPSD	COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	P04637	TP53	P24941	CDK2	S33	Q38L	38	Missense	distal	5	no	15.549	15.629	EPSD	COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	P04637	TP53	P24941	CDK2	S33	S37T	37	Missense	distal	4	no	15.549	15.818	EPSD	COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	P04637	TP53	P24941	CDK2	S33	L26P	26	Missense	distal	-7	no	15.549	15.544	EPSD	COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	P04637	TP53	P24941	CDK2	S33	P36S	36	Missense	distal	3	no	15.549	15.583	EPSD	COSMIC;GDSC;CCLE	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	P04637	TP53	P24941	CDK2	S33	A39V	39	Missense	distal	6	no	15.549	15.552	EPSD	COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	P04637	TP53	P24941	CDK2	S33	A39S	39	Missense	distal	6	no	15.549	15.555	EPSD	COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	P04637	TP53	P24941	CDK2	S33	N30K	30	Missense	distal	-3	no	15.549	15.488	EPSD	COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	P04637	TP53	P24941	CDK2	S33	A39T	39	Missense	distal	6	no	15.549	15.561	EPSD	COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	P04637	TP53	P24941	CDK2	S33	P36R	36	Missense	distal	3	no	15.549	17.268	EPSD	COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	P04637	TP53	P24941	CDK2	S33	L35R	35	Missense	proximal	2	no	15.549	15.815	EPSD	COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	P04637	TP53	P24941	CDK2	S33	L35H	35	Missense	proximal	2	no	15.549	15.733	EPSD	COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	P04637	TP53	P24941	CDK2	S33	L35P	35	Missense	proximal	2	no	15.549	15.656	EPSD	COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	P04637	TP53	P24941	CDK2	S33	L35I	35	Missense	proximal	2	no	15.549	15.633	EPSD	COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	P04637	TP53	P24941	CDK2	S33	L35V	35	Missense	proximal	2	no	15.549	15.778	EPSD	COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	P04637	TP53	P24941	CDK2	S37	M40I	40	Missense	distal	3	no	9.176	8.748	EPSD	COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	P04637	TP53	P24941	CDK2	S37	P36L	36	Missense	proximal	-1	no	9.176	8.996	EPSD	COSMIC;GDSC;CCLE	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	P04637	TP53	P24941	CDK2	S37	S33T	33	Missense	distal	-4	no	9.176	8.988	EPSD	COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	P04637	TP53	P24941	CDK2	S37	D41N	41	Missense	distal	4	no	9.176	9.221	EPSD	COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	P04637	TP53	P24941	CDK2	S37	L35F	35	Missense	proximal	-2	no	9.176	8.287	EPSD	COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	P04637	TP53	P24941	CDK2	S37	Q38L	38	Missense	proximal	1	no	9.176	7.267	EPSD	COSMIC	8.148	Loss
CMGC_CDK_CDK2_CDK2_ST	P04637	TP53	P24941	CDK2	S37	M44I	44	Missense	distal	7	no	9.176	8.688	EPSD	COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	P04637	TP53	P24941	CDK2	S37	P36S	36	Missense	proximal	-1	no	9.176	8.705	EPSD	COSMIC;GDSC;CCLE	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	P04637	TP53	P24941	CDK2	S37	A39V	39	Missense	proximal	2	no	9.176	9.274	EPSD	COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	P04637	TP53	P24941	CDK2	S37	A39S	39	Missense	proximal	2	no	9.176	9.218	EPSD	COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	P04637	TP53	P24941	CDK2	S37	D42Y	42	Missense	distal	5	no	9.176	9.076	EPSD	COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	P04637	TP53	P24941	CDK2	S37	M44R	44	Missense	distal	7	no	9.176	9.120	EPSD	COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	P04637	TP53	P24941	CDK2	S37	M44V	44	Missense	distal	7	no	9.176	8.889	EPSD	COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	P04637	TP53	P24941	CDK2	S37	N30K	30	Missense	distal	-7	no	9.176	9.210	EPSD	COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	P04637	TP53	P24941	CDK2	S37	M44T	44	Missense	distal	7	no	9.176	8.327	EPSD	COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	P04637	TP53	P24941	CDK2	S37	A39T	39	Missense	proximal	2	no	9.176	8.974	EPSD	COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	P04637	TP53	P24941	CDK2	S37	L43F	43	Missense	distal	6	no	9.176	9.157	EPSD	COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	P04637	TP53	P24941	CDK2	S37	D41H	41	Missense	distal	4	no	9.176	9.003	EPSD	COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	P04637	TP53	P24941	CDK2	S37	P36R	36	Missense	proximal	-1	no	9.176	9.746	EPSD	COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	P04637	TP53	P24941	CDK2	S37	L35R	35	Missense	proximal	-2	no	9.176	8.164	EPSD	COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	P04637	TP53	P24941	CDK2	S37	L35H	35	Missense	proximal	-2	no	9.176	8.390	EPSD	COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	P04637	TP53	P24941	CDK2	S37	L35P	35	Missense	proximal	-2	no	9.176	9.400	EPSD	COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	P04637	TP53	P24941	CDK2	S37	L35I	35	Missense	proximal	-2	no	9.176	9.246	EPSD	COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	P04637	TP53	P24941	CDK2	S37	L35V	35	Missense	proximal	-2	no	9.176	8.750	EPSD	COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	P04637	TP53	P24941	CDK2	S37	D41E	41	Missense	distal	4	no	9.176	9.258	EPSD	COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	P04637	TP53	P24941	CDK2	S46	M40I	40	Missense	distal	-6	no	14.212	14.207	EPSD	COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	P04637	TP53	P24941	CDK2	S46	W53C	53	Missense	distal	7	no	14.212	13.964	EPSD	COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	P04637	TP53	P24941	CDK2	S46	W53G	53	Missense	distal	7	no	14.212	13.993	EPSD	COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	P04637	TP53	P24941	CDK2	S46	S46F	46	Missense	central	0	yes	14.212	0.000	EPSD	COSMIC	8.148	Loss
CMGC_CDK_CDK2_CDK2_ST	P04637	TP53	P24941	CDK2	S46	D49Y	49	Missense	distal	3	no	14.212	15.280	EPSD	COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	P04637	TP53	P24941	CDK2	S46	P47L	47	Missense	proximal	1	no	14.212	4.391	EPSD	COSMIC	8.148	Loss
CMGC_CDK_CDK2_CDK2_ST	P04637	TP53	P24941	CDK2	S46	D49H	49	Missense	distal	3	no	14.212	17.047	EPSD	COSMIC;GDSC;CCLE	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	P04637	TP53	P24941	CDK2	S46	P47S	47	Missense	proximal	1	no	14.212	2.946	EPSD	COSMIC	8.148	Loss
CMGC_CDK_CDK2_CDK2_ST	P04637	TP53	P24941	CDK2	S46	D41N	41	Missense	distal	-5	no	14.212	14.173	EPSD	COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	P04637	TP53	P24941	CDK2	S46	D48H	48	Missense	proximal	2	no	14.212	14.292	EPSD	COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	P04637	TP53	P24941	CDK2	S46	D49N	49	Missense	distal	3	no	14.212	15.463	EPSD	COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	P04637	TP53	P24941	CDK2	S46	M44I	44	Missense	proximal	-2	no	14.212	16.142	EPSD	COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	P04637	TP53	P24941	CDK2	S46	Q52H	52	Missense	distal	6	no	14.212	14.201	EPSD	COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	P04637	TP53	P24941	CDK2	S46	D49V	49	Missense	distal	3	no	14.212	16.634	EPSD	COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	P04637	TP53	P24941	CDK2	S46	A39V	39	Missense	distal	-7	no	14.212	14.067	EPSD	COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	P04637	TP53	P24941	CDK2	S46	A39S	39	Missense	distal	-7	no	14.212	13.867	EPSD	COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	P04637	TP53	P24941	CDK2	S46	D42Y	42	Missense	distal	-4	no	14.212	14.150	EPSD	COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	P04637	TP53	P24941	CDK2	S46	M44R	44	Missense	proximal	-2	no	14.212	15.060	EPSD	COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	P04637	TP53	P24941	CDK2	S46	S46P	46	Missense	central	0	yes	14.212	0.000	EPSD	COSMIC	8.148	Loss
CMGC_CDK_CDK2_CDK2_ST	P04637	TP53	P24941	CDK2	S46	M44V	44	Missense	proximal	-2	no	14.212	15.646	EPSD	COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	P04637	TP53	P24941	CDK2	S46	L45P	45	Missense	proximal	-1	no	14.212	14.391	EPSD	COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	P04637	TP53	P24941	CDK2	S46	M44T	44	Missense	proximal	-2	no	14.212	16.263	EPSD	COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	P04637	TP53	P24941	CDK2	S46	A39T	39	Missense	distal	-7	no	14.212	14.045	EPSD	COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	P04637	TP53	P24941	CDK2	S46	L43F	43	Missense	distal	-3	no	14.212	14.470	EPSD	COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	P04637	TP53	P24941	CDK2	S46	D41H	41	Missense	distal	-5	no	14.212	14.201	EPSD	COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	P04637	TP53	P24941	CDK2	S46	D49E	49	Missense	distal	3	no	14.212	16.647	EPSD	COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	P04637	TP53	P24941	CDK2	S46	D49G	49	Missense	distal	3	no	14.212	15.925	EPSD	COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	P04637	TP53	P24941	CDK2	S46	D48A	48	Missense	proximal	2	no	14.212	14.239	EPSD	COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	P04637	TP53	P24941	CDK2	S46	D48Y	48	Missense	proximal	2	no	14.212	14.273	EPSD	COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	P04637	TP53	P24941	CDK2	S46	D48E	48	Missense	proximal	2	no	14.212	14.311	EPSD	COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	P04637	TP53	P24941	CDK2	S46	D49I	49	Missense	distal	3	no	14.212	15.358	EPSD	COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	P04637	TP53	P24941	CDK2	S46	D41E	41	Missense	distal	-5	no	14.212	14.192	EPSD	COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	P04637	TP53	P24941	CDK2	T81	P77A	77	Missense	distal	-4	no	14.045	13.987	EPSD	COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	P04637	TP53	P24941	CDK2	T81	A76T	76	Missense	distal	-5	no	14.045	14.019	EPSD	COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	P04637	TP53	P24941	CDK2	T81	A83T	83	Missense	proximal	2	no	14.045	13.843	EPSD	COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	P04637	TP53	P24941	CDK2	T81	T81I	81	Missense	central	0	yes	14.045	0.000	EPSD	COSMIC	8.148	Loss
CMGC_CDK_CDK2_CDK2_ST	P04637	TP53	P24941	CDK2	T81	A84V	84	Missense	distal	3	no	14.045	15.166	EPSD	COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	P04637	TP53	P24941	CDK2	T81	P80L	80	Missense	proximal	-1	no	14.045	13.866	EPSD	COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	P04637	TP53	P24941	CDK2	T81	A86V	86	Missense	distal	5	no	14.045	14.002	EPSD	COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	P04637	TP53	P24941	CDK2	T81	P85S	85	Missense	distal	4	no	14.045	14.059	EPSD	COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	P04637	TP53	P24941	CDK2	T81	A79T	79	Missense	proximal	-2	no	14.045	13.996	EPSD	COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	P04637	TP53	P24941	CDK2	T81	A84G	84	Missense	distal	3	no	14.045	14.457	EPSD	COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	P04637	TP53	P24941	CDK2	T81	A78V	78	Missense	distal	-3	no	14.045	14.247	EPSD	COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	P04637	TP53	P24941	CDK2	T81	A78S	78	Missense	distal	-3	no	14.045	14.199	EPSD	COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	P04637	TP53	P24941	CDK2	T81	P87L	87	Missense	distal	6	no	14.045	14.047	EPSD	COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	P04637	TP53	P24941	CDK2	T81	P85L	85	Missense	distal	4	no	14.045	14.157	EPSD	COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	P04637	TP53	P24941	CDK2	T81	P82S	82	Missense	proximal	1	no	14.045	2.780	EPSD	COSMIC	8.148	Loss
CMGC_CDK_CDK2_CDK2_ST	P04637	TP53	P24941	CDK2	T81	P77S	77	Missense	distal	-4	no	14.045	14.400	EPSD	COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	P04637	TP53	P24941	CDK2	T81	P80S	80	Missense	proximal	-1	no	14.045	13.574	EPSD	COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	P04637	TP53	P24941	CDK2	T81	A84T	84	Missense	distal	3	no	14.045	14.443	EPSD	COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	P04637	TP53	P24941	CDK2	T81	A83E	83	Missense	proximal	2	no	14.045	14.118	EPSD	COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	P04637	TP53	P24941	CDK2	T81	P85T	85	Missense	distal	4	no	14.045	14.328	EPSD	COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	P04637	TP53	P24941	CDK2	T81	A74V	74	Missense	distal	-7	no	14.045	13.901	EPSD	COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	P04637	TP53	P24941	CDK2	T81	P75S	75	Missense	distal	-6	no	14.045	14.044	EPSD	COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	P04637	TP53	P24941	CDK2	T81	A76V	76	Missense	distal	-5	no	14.045	14.052	EPSD	COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	P04637	TP53	P24941	CDK2	T81	P75R	75	Missense	distal	-6	no	14.045	14.047	EPSD	COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	P04637	TP53	P24941	CDK2	T81	P87H	87	Missense	distal	6	no	14.045	14.041	EPSD	COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	P04637	TP53	P24941	CDK2	T81	P87T	87	Missense	distal	6	no	14.045	14.053	EPSD	COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	P04637	TP53	P24941	CDK2	T81	P87S	87	Missense	distal	6	no	14.045	14.047	EPSD	COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	P04637	TP53	P24941	CDK2	T81	P87R	87	Missense	distal	6	no	14.045	14.029	EPSD	COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	P04637	TP53	P24941	CDK2	T81	P87C	87	Missense	distal	6	no	14.045	14.032	EPSD	COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	P04637	TP53	P24941	CDK2	T81	A86E	86	Missense	distal	5	no	14.045	14.114	EPSD	COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	P04637	TP53	P24941	CDK2	T81	A86S	86	Missense	distal	5	no	14.045	13.935	EPSD	COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	P04637	TP53	P24941	CDK2	T81	A83V	83	Missense	proximal	2	no	14.045	14.143	EPSD	COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	P04637	TP53	P24941	CDK2	S127	C124W	124	Missense	distal	-3	no	15.119	15.286	EPSD	COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	P04637	TP53	P24941	CDK2	S127	C124F	124	Missense	distal	-3	no	15.119	15.203	EPSD	COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	P04637	TP53	P24941	CDK2	S127	C124S	124	Missense	distal	-3	no	15.119	15.112	EPSD	COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	P04637	TP53	P24941	CDK2	S127	S127A	127	Missense	central	0	yes	15.119	0.000	EPSD	COSMIC	8.148	Loss
CMGC_CDK_CDK2_CDK2_ST	P04637	TP53	P24941	CDK2	S127	S127L	127	Missense	central	0	yes	15.119	0.000	EPSD	COSMIC	8.148	Loss
CMGC_CDK_CDK2_CDK2_ST	P04637	TP53	P24941	CDK2	S127	C124T	124	Missense	distal	-3	no	15.119	14.977	EPSD	COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	P04637	TP53	P24941	CDK2	S127	S127I	127	Missense	central	0	yes	15.119	0.000	EPSD	COSMIC	8.148	Loss
CMGC_CDK_CDK2_CDK2_ST	P04637	TP53	P24941	CDK2	S127	S127G	127	Missense	central	0	yes	15.119	0.000	EPSD	COSMIC	8.148	Loss
CMGC_CDK_CDK2_CDK2_ST	P04637	TP53	P24941	CDK2	S127	N131H	131	Missense	distal	4	no	15.119	14.902	EPSD	COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	P04637	TP53	P24941	CDK2	S127	N131D	131	Missense	distal	4	no	15.119	15.074	EPSD	COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	P04637	TP53	P24941	CDK2	S127	T125I	125	Missense	proximal	-2	no	15.119	14.999	EPSD	COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	P04637	TP53	P24941	CDK2	S127	F134I	134	Missense	distal	7	no	15.119	14.475	EPSD	COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	P04637	TP53	P24941	CDK2	S127	K120T	120	Missense	distal	-7	no	15.119	15.164	EPSD	COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	P04637	TP53	P24941	CDK2	S127	F134S	134	Missense	distal	7	no	15.119	14.266	EPSD	COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	P04637	TP53	P24941	CDK2	S127	T125K	125	Missense	proximal	-2	no	15.119	14.638	EPSD	COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	P04637	TP53	P24941	CDK2	S127	M133I	133	Missense	distal	6	no	15.119	15.138	EPSD	COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	P04637	TP53	P24941	CDK2	S127	N131K	131	Missense	distal	4	no	15.119	15.541	EPSD	COSMIC;CCLE	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	P04637	TP53	P24941	CDK2	S127	P128S	128	Missense	proximal	1	no	15.119	3.854	EPSD	COSMIC	8.148	Loss
CMGC_CDK_CDK2_CDK2_ST	P04637	TP53	P24941	CDK2	S127	M133L	133	Missense	distal	6	no	15.119	15.139	EPSD	COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	P04637	TP53	P24941	CDK2	S127	A129T	129	Missense	proximal	2	no	15.119	14.917	EPSD	COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	P04637	TP53	P24941	CDK2	S127	T123I	123	Missense	distal	-4	no	15.119	14.802	EPSD	COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	P04637	TP53	P24941	CDK2	S127	A129G	129	Missense	proximal	2	no	15.119	15.212	EPSD	COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	P04637	TP53	P24941	CDK2	S127	K132W	132	Missense	distal	5	no	15.119	15.446	EPSD	COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	P04637	TP53	P24941	CDK2	S127	A129V	129	Missense	proximal	2	no	15.119	15.217	EPSD	COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	P04637	TP53	P24941	CDK2	S127	P128A	128	Missense	proximal	1	no	15.119	0.716	EPSD	COSMIC	8.148	Loss
CMGC_CDK_CDK2_CDK2_ST	P04637	TP53	P24941	CDK2	S127	L130I	130	Missense	distal	3	no	15.119	14.835	EPSD	COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	P04637	TP53	P24941	CDK2	S127	S121F	121	Missense	distal	-6	no	15.119	15.124	EPSD	COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	P04637	TP53	P24941	CDK2	S127	A129D	129	Missense	proximal	2	no	15.119	15.092	EPSD	COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	P04637	TP53	P24941	CDK2	S127	K120Q	120	Missense	distal	-7	no	15.119	15.124	EPSD	COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	P04637	TP53	P24941	CDK2	S127	T125S	125	Missense	proximal	-2	no	15.119	14.502	EPSD	COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	P04637	TP53	P24941	CDK2	S127	P128L	128	Missense	proximal	1	no	15.119	5.298	EPSD	COSMIC	8.148	Loss
CMGC_CDK_CDK2_CDK2_ST	P04637	TP53	P24941	CDK2	S127	V122L	122	Missense	distal	-5	no	15.119	15.100	EPSD	COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	P04637	TP53	P24941	CDK2	S127	C124L	124	Missense	distal	-3	no	15.119	14.945	EPSD	COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	P04637	TP53	P24941	CDK2	S127	N131T	131	Missense	distal	4	no	15.119	15.422	EPSD	COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	P04637	TP53	P24941	CDK2	S127	M133V	133	Missense	distal	6	no	15.119	15.137	EPSD	COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	P04637	TP53	P24941	CDK2	T150	P151N	151	Missense	proximal	1	no	10.420	-30.192	EPSD	COSMIC	8.148	Loss
CMGC_CDK_CDK2_CDK2_ST	P04637	TP53	P24941	CDK2	T150	P152A	152	Missense	proximal	2	no	10.420	10.445	EPSD	COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	P04637	TP53	P24941	CDK2	T150	P152T	152	Missense	proximal	2	no	10.420	10.243	EPSD	COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	P04637	TP53	P24941	CDK2	T150	P152H	152	Missense	proximal	2	no	10.420	10.498	EPSD	COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	P04637	TP53	P24941	CDK2	T150	P153T	153	Missense	distal	3	no	10.420	10.306	EPSD	COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	P04637	TP53	P24941	CDK2	T150	V147I	147	Missense	distal	-3	no	10.420	10.297	EPSD	COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	P04637	TP53	P24941	CDK2	T150	P153L	153	Missense	distal	3	no	10.420	10.037	EPSD	COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	P04637	TP53	P24941	CDK2	T150	V147D	147	Missense	distal	-3	no	10.420	10.343	EPSD	COSMIC;GDSC;CCLE	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	P04637	TP53	P24941	CDK2	T150	S149P	149	Missense	proximal	-1	no	10.420	10.891	EPSD	COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	P04637	TP53	P24941	CDK2	T150	P152K	152	Missense	proximal	2	no	10.420	10.279	EPSD	COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	P04637	TP53	P24941	CDK2	T150	P153S	153	Missense	distal	3	no	10.420	10.454	EPSD	COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	P04637	TP53	P24941	CDK2	T150	G154C	154	Missense	distal	4	no	10.420	9.793	EPSD	COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	P04637	TP53	P24941	CDK2	T150	S149F	149	Missense	proximal	-1	no	10.420	11.677	EPSD	COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	P04637	TP53	P24941	CDK2	T150	G154D	154	Missense	distal	4	no	10.420	10.475	EPSD	COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	P04637	TP53	P24941	CDK2	T150	V157I	157	Missense	distal	7	no	10.420	10.219	EPSD	COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	P04637	TP53	P24941	CDK2	T150	W146R	146	Missense	distal	-4	no	10.420	11.178	EPSD	COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	P04637	TP53	P24941	CDK2	T150	Q144R	144	Missense	distal	-6	no	10.420	10.419	EPSD	COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	P04637	TP53	P24941	CDK2	T150	D148V	148	Missense	proximal	-2	no	10.420	9.905	EPSD	COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	P04637	TP53	P24941	CDK2	T150	S149Y	149	Missense	proximal	-1	no	10.420	11.330	EPSD	COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	P04637	TP53	P24941	CDK2	T150	T150I	150	Missense	central	0	yes	10.420	0.000	EPSD	COSMIC	8.148	Loss
CMGC_CDK_CDK2_CDK2_ST	P04637	TP53	P24941	CDK2	T150	S149T	149	Missense	proximal	-1	no	10.420	10.628	EPSD	COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	P04637	TP53	P24941	CDK2	T150	W146G	146	Missense	distal	-4	no	10.420	11.103	EPSD	COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	P04637	TP53	P24941	CDK2	T150	L145M	145	Missense	distal	-5	no	10.420	10.515	EPSD	COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	P04637	TP53	P24941	CDK2	T150	V143L	143	Missense	distal	-7	no	10.420	10.406	EPSD	COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	P04637	TP53	P24941	CDK2	T150	R156S	156	Missense	distal	6	no	10.420	10.438	EPSD	COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	P04637	TP53	P24941	CDK2	T150	D148E	148	Missense	proximal	-2	no	10.420	9.440	EPSD	COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	P04637	TP53	P24941	CDK2	T150	V147F	147	Missense	distal	-3	no	10.420	10.464	EPSD	COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	P04637	TP53	P24941	CDK2	T150	T155A	155	Missense	distal	5	no	10.420	10.456	EPSD	COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	P04637	TP53	P24941	CDK2	T150	V147E	147	Missense	distal	-3	no	10.420	10.452	EPSD	COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	P04637	TP53	P24941	CDK2	T150	G154I	154	Missense	distal	4	no	10.420	10.512	EPSD	COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	P04637	TP53	P24941	CDK2	T150	D148G	148	Missense	proximal	-2	no	10.420	9.813	EPSD	COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	P04637	TP53	P24941	CDK2	T150	Q144K	144	Missense	distal	-6	no	10.420	10.417	EPSD	COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	P04637	TP53	P24941	CDK2	T150	V147A	147	Missense	distal	-3	no	10.420	10.219	EPSD	COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	P04637	TP53	P24941	CDK2	T150	L145V	145	Missense	distal	-5	no	10.420	10.440	EPSD	COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	P04637	TP53	P24941	CDK2	T150	T150K	150	Missense	central	0	yes	10.420	0.000	EPSD	COSMIC	8.148	Loss
CMGC_CDK_CDK2_CDK2_ST	P04637	TP53	P24941	CDK2	T150	P153H	153	Missense	distal	3	no	10.420	11.442	EPSD	COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	P04637	TP53	P24941	CDK2	T150	V157E	157	Missense	distal	7	no	10.420	10.206	EPSD	COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	P04637	TP53	P24941	CDK2	T150	T155S	155	Missense	distal	5	no	10.420	10.345	EPSD	COSMIC;CCLE	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	P04637	TP53	P24941	CDK2	T150	D148H	148	Missense	proximal	-2	no	10.420	9.545	EPSD	COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	P04637	TP53	P24941	CDK2	T150	P153A	153	Missense	distal	3	no	10.420	9.908	EPSD	COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	P04637	TP53	P24941	CDK2	T150	T150R	150	Missense	central	0	yes	10.420	0.000	EPSD	COSMIC	8.148	Loss
CMGC_CDK_CDK2_CDK2_ST	P04637	TP53	P24941	CDK2	T150	T155L	155	Missense	distal	5	no	10.420	10.486	EPSD	COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	P04637	TP53	P24941	CDK2	T150	G154A	154	Missense	distal	4	no	10.420	10.580	EPSD	COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	P04637	TP53	P24941	CDK2	T150	T150A	150	Missense	central	0	yes	10.420	0.000	EPSD	COSMIC	8.148	Loss
CMGC_CDK_CDK2_CDK2_ST	P04637	TP53	P24941	CDK2	T150	W146C	146	Missense	distal	-4	no	10.420	10.669	EPSD	COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	P04637	TP53	P24941	CDK2	T150	P153F	153	Missense	distal	3	no	10.420	10.379	EPSD	COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	P04637	TP53	P24941	CDK2	T150	D148Y	148	Missense	proximal	-2	no	10.420	9.991	EPSD	COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	P04637	TP53	P24941	CDK2	S314	S315P	315	Missense	proximal	1	no	4.769	16.035	EPSD	COSMIC	8.148	Gain
CMGC_CDK_CDK2_CDK2_ST	P04637	TP53	P24941	CDK2	S315	N310T	310	Missense	distal	-5	no	14.293	14.272	PhosphoSitePlus	COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	P04637	TP53	P24941	CDK2	S315	Q317R	317	Missense	proximal	2	no	14.293	14.392	PhosphoSitePlus	COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	P04637	TP53	P24941	CDK2	S315	P309S	309	Missense	distal	-6	no	14.293	14.292	PhosphoSitePlus	COSMIC;GDSC;CCLE	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	P04637	TP53	P24941	CDK2	S315	K319E	319	Missense	distal	4	no	14.293	13.908	PhosphoSitePlus	COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	P04637	TP53	P24941	CDK2	S315	P322L	322	Missense	distal	7	no	14.293	14.323	PhosphoSitePlus	COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	P04637	TP53	P24941	CDK2	S315	K320N	320	Missense	distal	5	no	14.293	14.450	PhosphoSitePlus	COSMIC;GDSC;CCLE	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	P04637	TP53	P24941	CDK2	S315	N310L	310	Missense	distal	-5	no	14.293	14.285	PhosphoSitePlus	COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	P04637	TP53	P24941	CDK2	S315	T312S	312	Missense	distal	-3	no	14.293	14.427	PhosphoSitePlus	COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	P04637	TP53	P24941	CDK2	S315	N311Y	311	Missense	distal	-4	no	14.293	14.620	PhosphoSitePlus	COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	P04637	TP53	P24941	CDK2	S315	P322R	322	Missense	distal	7	no	14.293	14.782	PhosphoSitePlus	COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	P04637	TP53	P24941	CDK2	S315	N311K	311	Missense	distal	-4	no	14.293	14.073	PhosphoSitePlus	COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	P04637	TP53	P24941	CDK2	S315	Q317K	317	Missense	proximal	2	no	14.293	14.092	PhosphoSitePlus	COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	P04637	TP53	P24941	CDK2	S315	S315P	315	Missense	central	0	yes	14.293	0.000	PhosphoSitePlus	COSMIC	8.148	Loss
CMGC_CDK_CDK2_CDK2_ST	P04637	TP53	P24941	CDK2	S315	N310H	310	Missense	distal	-5	no	14.293	14.321	PhosphoSitePlus	COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	P04637	TP53	P24941	CDK2	S315	S314C	314	Missense	proximal	-1	no	14.293	14.636	PhosphoSitePlus	COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	P04637	TP53	P24941	CDK2	S315	P318A	318	Missense	distal	3	no	14.293	13.781	PhosphoSitePlus	COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	P04637	TP53	P24941	CDK2	S315	P316L	316	Missense	proximal	1	no	14.293	4.472	PhosphoSitePlus	COSMIC	8.148	Loss
CMGC_CDK_CDK2_CDK2_ST	P04637	TP53	P24941	CDK2	S315	L308M	308	Missense	distal	-7	no	14.293	14.788	PhosphoSitePlus	COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	P04637	TP53	P24941	CDK2	S315	S313C	313	Missense	proximal	-2	no	14.293	13.882	PhosphoSitePlus	COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	P04637	TP53	P24941	CDK2	S315	N311H	311	Missense	distal	-4	no	14.293	13.550	PhosphoSitePlus	COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	P04637	TP53	P24941	CDK2	S315	L308V	308	Missense	distal	-7	no	14.293	14.307	PhosphoSitePlus	COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	P04637	TP53	P24941	CDK2	S315	S314F	314	Missense	proximal	-1	no	14.293	15.549	PhosphoSitePlus	COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	P04637	TP53	P24941	CDK2	S315	K319R	319	Missense	distal	4	no	14.293	13.771	PhosphoSitePlus	COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	P04637	TP53	P24941	CDK2	S315	T312A	312	Missense	distal	-3	no	14.293	14.274	PhosphoSitePlus	COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	P04637	TP53	P24941	CDK2	S315	N310D	310	Missense	distal	-5	no	14.293	14.331	PhosphoSitePlus	COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	P04637	TP53	P24941	CDK2	S315	N311D	311	Missense	distal	-4	no	14.293	14.681	PhosphoSitePlus	COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	P04637	TP53	P24941	CDK2	S315	P309R	309	Missense	distal	-6	no	14.293	14.295	PhosphoSitePlus	COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	P04637	TP53	P24941	CDK2	S315	S313N	313	Missense	proximal	-2	no	14.293	13.601	PhosphoSitePlus	COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	P04637	TP53	P24941	CDK2	S315	Q317P	317	Missense	proximal	2	no	14.293	14.234	PhosphoSitePlus	COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	P04637	TP53	P24941	CDK2	S315	P316S	316	Missense	proximal	1	no	14.293	3.027	PhosphoSitePlus	COSMIC	8.148	Loss
CMGC_CDK_CDK2_CDK2_ST	P04637	TP53	P24941	CDK2	S367	S367F	367	Missense	central	0	yes	8.674	0.000	EPSD	COSMIC	8.148	Loss
CMGC_CDK_CDK2_CDK2_ST	P04637	TP53	P24941	CDK2	S367	K370N	370	Missense	distal	3	no	8.674	5.404	EPSD	COSMIC	8.148	Loss
CMGC_CDK_CDK2_CDK2_ST	P04637	TP53	P24941	CDK2	S367	G361E	361	Missense	distal	-6	no	8.674	8.675	EPSD	COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	P04637	TP53	P24941	CDK2	S367	A364D	364	Missense	distal	-3	no	8.674	8.798	EPSD	COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	P04637	TP53	P24941	CDK2	S367	H365Y	365	Missense	proximal	-2	no	8.674	9.120	EPSD	COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	P04637	TP53	P24941	CDK2	S367	G360A	360	Missense	distal	-7	no	8.674	8.515	EPSD	COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	P04637	TP53	P24941	CDK2	S367	A364T	364	Missense	distal	-3	no	8.674	8.693	EPSD	COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	P04637	TP53	P24941	CDK2	S367	S366A	366	Missense	proximal	-1	no	8.674	8.875	EPSD	COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	P04637	TP53	P24941	CDK2	S367	K370Q	370	Missense	distal	3	no	8.674	5.942	EPSD	COSMIC	8.148	Loss
CMGC_CDK_CDK2_CDK2_ST	P04637	TP53	P24941	CDK2	S367	K373R	373	Missense	distal	6	no	8.674	8.650	EPSD	COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	P04637	TP53	P24941	CDK2	S367	G374S	374	Missense	distal	7	no	8.674	7.852	EPSD	COSMIC	8.148	Loss
CMGC_CDK_CDK2_CDK2_ST	P04637	TP53	P24941	CDK2	S367	S371P	371	Missense	distal	4	no	8.674	8.661	EPSD	COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	P04637	TP53	P24941	CDK2	S378	R379H	379	Missense	proximal	1	no	7.647	10.687	EPSD	COSMIC	8.148	Gain
CMGC_CDK_CDK2_CDK2_ST	P04637	TP53	P24941	CDK2	S378	S376T	376	Missense	proximal	-2	no	7.647	8.265	EPSD	COSMIC	8.148	Gain
CMGC_CDK_CDK2_CDK2_ST	P04637	TP53	P24941	CDK2	S378	R379P	379	Missense	proximal	1	no	7.647	17.445	EPSD	COSMIC	8.148	Gain
CMGC_CDK_CDK2_CDK2_ST	P04637	TP53	P24941	CDK2	S378	G374S	374	Missense	distal	-4	no	7.647	8.320	EPSD	COSMIC	8.148	Gain
CMGC_CDK_CDK2_CDK2_ST	P04637	TP53	P24941	CDK2	S378	S376A	376	Missense	proximal	-2	no	7.647	8.314	EPSD	COSMIC	8.148	Gain
CMGC_CDK_CDK2_CDK2_ST	Q9C0D5	TANC1	P24941	CDK2	S29	P30L	30	Missense	proximal	1	no	12.404	2.583	EPSD	COSMIC	8.148	Loss
CMGC_CDK_CDK2_CDK2_ST	Q9C0D5	TANC1	P24941	CDK2	S67	S66F	66	Missense	proximal	-1	no	13.809	15.066	EPSD	COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	Q9C0D5	TANC1	P24941	CDK2	S85	K83R	83	Missense	proximal	-2	no	13.901	13.180	EPSD	COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	Q9C0D5	TANC1	P24941	CDK2	S85	V81G	81	Missense	distal	-4	no	13.901	13.631	EPSD	COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	Q9C0D5	TANC1	P24941	CDK2	S132	D126Y	126	Missense	distal	-6	no	12.632	12.634	EPSD	COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	Q9C0D5	TANC1	P24941	CDK2	S174	C176G	176	Missense	proximal	2	no	12.827	12.799	EPSD	COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	Q9C0D5	TANC1	P24941	CDK2	S185	S187R	187	Missense	proximal	2	no	13.043	13.135	EPSD	COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	Q9C0D5	TANC1	P24941	CDK2	S185	S187C	187	Missense	proximal	2	no	13.043	13.122	EPSD	COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	Q9C0D5	TANC1	P24941	CDK2	S185	T188I	188	Missense	distal	3	no	13.043	12.489	EPSD	COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	Q9C0D5	TANC1	P24941	CDK2	S214	P215H	215	Missense	proximal	1	no	12.466	5.707	EPSD	COSMIC	8.148	Loss
CMGC_CDK_CDK2_CDK2_ST	Q9C0D5	TANC1	P24941	CDK2	S240	E235K	235	Missense	distal	-5	no	8.777	8.743	EPSD	COSMIC;GDSC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	Q9C0D5	TANC1	P24941	CDK2	S444	S447L	447	Missense	distal	3	no	14.217	13.800	EPSD	COSMIC;GDSC;CCLE	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	Q9C0D5	TANC1	P24941	CDK2	S448	S447L	447	Missense	proximal	-1	no	11.399	11.690	EPSD	COSMIC;GDSC;CCLE	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	Q9C0D5	TANC1	P24941	CDK2	S465	S471R	471	Missense	distal	6	no	14.984	14.967	EPSD	COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	Q9C0D5	TANC1	P24941	CDK2	T478	S471R	471	Missense	distal	-7	no	14.736	15.259	EPSD	COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	Q9C0D5	TANC1	P24941	CDK2	T478	S474N	474	Missense	distal	-4	no	14.736	14.520	EPSD	COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	Q9C0D5	TANC1	P24941	CDK2	T910	V913M	913	Missense	distal	3	no	14.257	13.409	EPSD	COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	Q9C0D5	TANC1	P24941	CDK2	T910	R906M	906	Missense	distal	-4	no	14.257	13.752	EPSD	COSMIC;GDSC;CCLE	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	Q9C0D5	TANC1	P24941	CDK2	T910	S916N	916	Missense	distal	6	no	14.257	14.259	EPSD	COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	Q9C0D5	TANC1	P24941	CDK2	T1147	R1146Q	1146	Missense	proximal	-1	no	12.183	11.305	EPSD	COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	Q9C0D5	TANC1	P24941	CDK2	T1147	Q1144R	1144	Missense	distal	-3	no	12.183	12.314	EPSD	COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	Q9C0D5	TANC1	P24941	CDK2	T1147	A1153V	1153	Missense	distal	6	no	12.183	12.186	EPSD	COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	Q9C0D5	TANC1	P24941	CDK2	S1503	K1498N	1498	Missense	distal	-5	no	13.796	13.812	EPSD	COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	Q9C0D5	TANC1	P24941	CDK2	S1564	P1562H	1562	Missense	proximal	-2	no	14.039	13.029	PhosphoSitePlus	COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	Q9C0D5	TANC1	P24941	CDK2	S1564	G1568V	1568	Missense	distal	4	no	14.039	14.386	PhosphoSitePlus	COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	Q9C0D5	TANC1	P24941	CDK2	S1564	P1565L	1565	Missense	proximal	1	no	14.039	4.218	PhosphoSitePlus	COSMIC	8.148	Loss
CMGC_CDK_CDK2_CDK2_ST	Q9C0D5	TANC1	P24941	CDK2	S1564	A1571V	1571	Missense	distal	7	no	14.039	13.912	PhosphoSitePlus	COSMIC;GDSC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	Q9C0D5	TANC1	P24941	CDK2	T1573	G1568V	1568	Missense	distal	-5	no	15.927	15.878	EPSD	COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	Q9C0D5	TANC1	P24941	CDK2	T1573	A1571V	1571	Missense	proximal	-2	no	15.927	15.261	EPSD	COSMIC;GDSC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	Q9C0D5	TANC1	P24941	CDK2	T1573	S1577N	1577	Missense	distal	4	no	15.927	15.893	EPSD	COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	Q9C0D5	TANC1	P24941	CDK2	S1668	P1669L	1669	Missense	proximal	1	no	13.364	3.543	EPSD	COSMIC	8.148	Loss
CMGC_CDK_CDK2_CDK2_ST	P51649	ALDH5A1	P24941	CDK2	T181	I179L	179	Missense	proximal	-2	no	19.210	19.139	PhosphoSitePlus	COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	Q5JTV8	TOR1AIP1	P24941	CDK2	T20	P21L	21	Missense	proximal	1	no	12.521	2.700	EPSD	COSMIC	8.148	Loss
CMGC_CDK_CDK2_CDK2_ST	Q5JTV8	TOR1AIP1	P24941	CDK2	S79	P72S	72	Missense	distal	-7	no	12.511	12.331	EPSD	COSMIC;CCLE	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	Q5JTV8	TOR1AIP1	P24941	CDK2	S143	P142L	142	Missense	proximal	-1	no	14.622	14.442	PhosphoSitePlus	COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	Q5JTV8	TOR1AIP1	P24941	CDK2	S143	S143F	143	Missense	central	0	yes	14.622	0.000	PhosphoSitePlus	COSMIC;GDSC	8.148	Loss
CMGC_CDK_CDK2_CDK2_ST	Q5JTV8	TOR1AIP1	P24941	CDK2	S143	R148G	148	Missense	distal	5	no	14.622	14.642	PhosphoSitePlus	COSMIC;GDSC;CCLE	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	Q5JTV8	TOR1AIP1	P24941	CDK2	S143	R149K	149	Missense	distal	6	no	14.622	14.647	PhosphoSitePlus	COSMIC;GDSC;CCLE	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	Q5JTV8	TOR1AIP1	P24941	CDK2	S143	M146I	146	Missense	distal	3	no	14.622	14.194	PhosphoSitePlus	COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	Q5JTV8	TOR1AIP1	P24941	CDK2	S143	S143L	143	Missense	central	0	yes	14.622	0.000	PhosphoSitePlus	COSMIC	8.148	Loss
CMGC_CDK_CDK2_CDK2_ST	Q5JTV8	TOR1AIP1	P24941	CDK2	S228	S228F	228	Missense	central	0	yes	9.722	0.000	EPSD	COSMIC	8.148	Loss
CMGC_CDK_CDK2_CDK2_ST	Q5JTV8	TOR1AIP1	P24941	CDK2	S228	S230I	230	Missense	proximal	2	no	9.722	9.632	EPSD	COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	Q5JTV8	TOR1AIP1	P24941	CDK2	S228	T234A	234	Missense	distal	6	no	9.722	9.710	EPSD	COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	Q5JTV8	TOR1AIP1	P24941	CDK2	S245	D243Y	243	Missense	proximal	-2	no	10.099	9.669	EPSD	COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	Q5JTV8	TOR1AIP1	P24941	CDK2	S245	R238I	238	Missense	distal	-7	no	10.099	9.950	EPSD	COSMIC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	Q5JTV8	TOR1AIP1	P24941	CDK2	S245	S245Y	245	Missense	central	0	yes	10.099	0.000	EPSD	COSMIC	8.148	Loss
CMGC_CDK_CDK2_CDK2_ST	Q5JTV8	TOR1AIP1	P24941	CDK2	T286	G282V	282	Missense	distal	-4	no	11.226	11.496	EPSD	COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	Q5JTV8	TOR1AIP1	P24941	CDK2	T286	W290L	290	Missense	distal	4	no	11.226	11.819	EPSD	COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	Q5JTV8	TOR1AIP1	P24941	CDK2	T286	Q293H	293	Missense	distal	7	no	11.226	11.513	EPSD	COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	Q5JTV8	TOR1AIP1	P24941	CDK2	S315	S319P	319	Missense	distal	4	no	10.929	10.916	EPSD	COSMIC;CCLE	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	Q5JTV8	TOR1AIP1	P24941	CDK2	S315	S320P	320	Missense	distal	5	no	10.929	11.030	EPSD	COSMIC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	Q5JTV8	TOR1AIP1	P24941	CDK2	T318	S319P	319	Missense	proximal	1	no	5.566	16.832	EPSD	COSMIC;CCLE	8.148	Gain
CMGC_CDK_CDK2_CDK2_ST	Q5JTV8	TOR1AIP1	P24941	CDK2	S319	S320P	320	Missense	proximal	1	no	3.134	14.400	EPSD	COSMIC	8.148	Gain
CMGC_CDK_CDK2_CDK2_ST	Q8TAP6	CEP76	P24941	CDK2	T335	R331W	331	Missense	distal	-4	no	17.340	16.582	EPSD	COSMIC	8.148	Down-regulation
Atypical_Alpha_eEF2K_EEF2K_ST	P13639	EEF2	O00418	EEF2K	T54	E53K	53	Missense	proximal	-1	no	88.276	88.136	EPSD	COSMIC	53.998	Down-regulation
Atypical_Alpha_eEF2K_EEF2K_ST	P13639	EEF2	O00418	EEF2K	T57	E53K	53	Missense	distal	-4	no	90.548	91.778	PhosphoSitePlus	COSMIC	53.998	Up-regulation
Atypical_Alpha_eEF2K_EEF2K_ST	P13639	EEF2	O00418	EEF2K	T59	E53K	53	Missense	distal	-6	no	87.039	86.093	EPSD	COSMIC	53.998	Down-regulation
Atypical_Alpha_eEF2K_EEF2K_ST	O00418	EEF2K	O00418	EEF2K	T348	L343P	343	Missense	distal	-5	no	105.565	109.155	EPSD;PhosphoSitePlus	COSMIC	53.998	Up-regulation
Atypical_Alpha_eEF2K_EEF2K_ST	O00418	EEF2K	O00418	EEF2K	T348	E355K	355	Missense	distal	7	no	105.565	107.960	EPSD;PhosphoSitePlus	COSMIC	53.998	Up-regulation
Atypical_Alpha_eEF2K_EEF2K_ST	O00418	EEF2K	O00418	EEF2K	T348	I349V	349	Missense	proximal	1	no	105.565	104.390	EPSD;PhosphoSitePlus	COSMIC	53.998	Down-regulation
Atypical_Alpha_eEF2K_EEF2K_ST	O00418	EEF2K	O00418	EEF2K	T353	E355K	355	Missense	proximal	2	no	92.253	93.169	EPSD;PhosphoSitePlus	COSMIC	53.998	Up-regulation
Atypical_Alpha_eEF2K_EEF2K_ST	O00418	EEF2K	O00418	EEF2K	T353	I349V	349	Missense	distal	-4	no	92.253	91.767	EPSD;PhosphoSitePlus	COSMIC	53.998	Down-regulation
Atypical_Alpha_eEF2K_EEF2K_ST	O00418	EEF2K	O00418	EEF2K	S366	T364N	364	Missense	proximal	-2	no	100.807	97.058	EPSD;PhosphoSitePlus	COSMIC	53.998	Down-regulation
Atypical_Alpha_eEF2K_EEF2K_ST	O00418	EEF2K	O00418	EEF2K	S396	S398C	398	Missense	proximal	2	no	101.933	102.994	PhosphoSitePlus;EPSD	COSMIC	53.998	Up-regulation
Atypical_Alpha_eEF2K_EEF2K_ST	O00418	EEF2K	O00418	EEF2K	S396	T389I	389	Missense	distal	-7	no	101.933	95.334	PhosphoSitePlus;EPSD	COSMIC	53.998	Down-regulation
Atypical_Alpha_eEF2K_EEF2K_ST	O00418	EEF2K	O00418	EEF2K	S396	S399L	399	Missense	distal	3	no	101.933	78.412	PhosphoSitePlus;EPSD	COSMIC	53.998	Down-regulation
Atypical_Alpha_eEF2K_EEF2K_ST	O00418	EEF2K	O00418	EEF2K	S396	P394L	394	Missense	proximal	-2	no	101.933	98.213	PhosphoSitePlus;EPSD	COSMIC;GDSC;CCLE	53.998	Down-regulation
Atypical_Alpha_eEF2K_EEF2K_ST	O00418	EEF2K	O00418	EEF2K	S396	P394S	394	Missense	proximal	-2	no	101.933	102.027	PhosphoSitePlus;EPSD	COSMIC	53.998	Up-regulation
Atypical_Alpha_eEF2K_EEF2K_ST	O00418	EEF2K	O00418	EEF2K	S441	E446D	446	Missense	distal	5	no	90.329	89.959	EPSD;PhosphoSitePlus	COSMIC	53.998	Down-regulation
Atypical_Alpha_eEF2K_EEF2K_ST	O00418	EEF2K	O00418	EEF2K	S445	E446D	446	Missense	proximal	1	no	106.516	104.623	EPSD;PhosphoSitePlus	COSMIC	53.998	Down-regulation
Atypical_Alpha_eEF2K_EEF2K_ST	O00418	EEF2K	O00418	EEF2K	S474	S478F	478	Missense	distal	4	no	112.113	114.512	EPSD;PhosphoSitePlus	COSMIC	53.998	Up-regulation
Atypical_Alpha_eEF2K_EEF2K_ST	O00418	EEF2K	O00418	EEF2K	S474	R480W	480	Missense	distal	6	no	112.113	110.231	EPSD;PhosphoSitePlus	COSMIC	53.998	Down-regulation
Atypical_Alpha_eEF2K_EEF2K_ST	O00418	EEF2K	O00418	EEF2K	S474	G476C	476	Missense	proximal	2	no	112.113	112.786	EPSD;PhosphoSitePlus	COSMIC	53.998	Up-regulation
Atypical_Alpha_eEF2K_EEF2K_ST	O00418	EEF2K	O00418	EEF2K	S492	R493C	493	Missense	proximal	1	no	54.735	56.801	EPSD	COSMIC	53.998	Up-regulation
Atypical_Alpha_eEF2K_EEF2K_ST	O00418	EEF2K	O00418	EEF2K	S500	A501S	501	Missense	proximal	1	no	98.317	95.091	EPSD;PhosphoSitePlus	COSMIC	53.998	Down-regulation
Atypical_Alpha_eEF2K_EEF2K_ST	O00418	EEF2K	O00418	EEF2K	S500	R493C	493	Missense	distal	-7	no	98.317	82.835	EPSD;PhosphoSitePlus	COSMIC	53.998	Down-regulation
Atypical_Alpha_eEF2K_EEF2K_ST	O00418	EEF2K	O00418	EEF2K	S500	S500L	500	Missense	central	0	yes	98.317	0.000	EPSD;PhosphoSitePlus	COSMIC	53.998	Loss
Atypical_Alpha_eEF2K_EEF2K_ST	O00418	EEF2K	O00418	EEF2K	S521	G524R	524	Missense	distal	3	no	42.962	55.626	EPSD	COSMIC	53.998	Gain
Atypical_Alpha_eEF2K_EEF2K_ST	O00418	EEF2K	O00418	EEF2K	S627	Q624L	624	Missense	distal	-3	no	52.783	57.087	EPSD	COSMIC	53.998	Gain
AGC_PKG_PRKG1_ST	P50552	VASP	Q13976	PRKG1	S239	G246V	246	Missense	distal	7	no	11.551	11.531	PhosphoSitePlus;EPSD	COSMIC	7.092	Down-regulation
AGC_PKG_PRKG1_ST	P50552	VASP	Q13976	PRKG1	S255	P248A	248	Missense	distal	-7	no	6.704	7.312	EPSD	COSMIC	7.092	Gain
AGC_PKG_PRKG1_ST	P50552	VASP	Q13976	PRKG1	T278	G281W	281	Missense	distal	3	no	9.874	9.964	EPSD;PhosphoSitePlus	COSMIC	7.092	Up-regulation
AGC_PKG_PRKG1_ST	P50552	VASP	Q13976	PRKG1	S305	S305C	305	Missense	central	0	yes	8.159	0.000	EPSD	COSMIC	7.092	Loss
AGC_PKG_PRKG1_ST	P50552	VASP	Q13976	PRKG1	S305	V299F	299	Missense	distal	-6	no	8.159	8.243	EPSD	COSMIC;CCLE	7.092	Up-regulation
AGC_PKG_PRKG1_ST	P50552	VASP	Q13976	PRKG1	S314	K321E	321	Missense	distal	7	no	7.455	7.371	EPSD	COSMIC	7.092	Down-regulation
AGC_PKG_PRKG1_ST	P50552	VASP	Q13976	PRKG1	S322	S325L	325	Missense	distal	3	no	11.110	11.478	EPSD	COSMIC	7.092	Up-regulation
AGC_PKG_PRKG1_ST	P50552	VASP	Q13976	PRKG1	S322	K321E	321	Missense	proximal	-1	no	11.110	10.949	EPSD	COSMIC	7.092	Down-regulation
AGC_PKG_PRKG1_ST	P50552	VASP	Q13976	PRKG1	S323	S325L	325	Missense	proximal	2	no	8.265	8.122	EPSD	COSMIC	7.092	Down-regulation
AGC_PKG_PRKG1_ST	P50552	VASP	Q13976	PRKG1	S323	K321E	321	Missense	proximal	-2	no	8.265	4.742	EPSD	COSMIC	7.092	Loss
AGC_PKG_PRKG1_ST	P61224	RAP1B	Q13976	PRKG1	S179	G173V	173	Missense	distal	-6	no	11.839	11.676	PhosphoSitePlus	COSMIC	7.092	Down-regulation
AGC_PKG_PRKG1_ST	P61224	RAP1B	Q13976	PRKG1	S180	G173V	173	Missense	distal	-7	no	10.845	10.501	EPSD	COSMIC	7.092	Down-regulation
AGC_PKG_PRKG1_ST	P43694	GATA4	Q13976	PRKG1	S262	R259Q	259	Missense	distal	-3	no	14.320	10.485	PhosphoSitePlus	COSMIC	7.092	Down-regulation
AGC_PKG_PRKG1_ST	P43694	GATA4	Q13976	PRKG1	S262	R260Q	260	Missense	proximal	-2	no	14.320	11.355	PhosphoSitePlus	COSMIC	7.092	Down-regulation
AGC_PKG_PRKG1_ST	P43694	GATA4	Q13976	PRKG1	S262	R259H	259	Missense	distal	-3	no	14.320	8.253	PhosphoSitePlus	COSMIC	7.092	Down-regulation
AGC_PKG_PRKG1_ST	P43694	GATA4	Q13976	PRKG1	S262	R265S	265	Missense	distal	3	no	14.320	14.385	PhosphoSitePlus	COSMIC	7.092	Up-regulation
AGC_PKG_PRKG1_ST	P43694	GATA4	Q13976	PRKG1	S262	R260H	260	Missense	proximal	-2	no	14.320	10.063	PhosphoSitePlus	COSMIC	7.092	Down-regulation
AGC_PKG_PRKG1_ST	P43694	GATA4	Q13976	PRKG1	S422	Q419H	419	Missense	distal	-3	no	7.320	5.088	EPSD	COSMIC	7.092	Loss
AGC_PKG_PRKG1_ST	P43694	GATA4	Q13976	PRKG1	S422	Q419L	419	Missense	distal	-3	no	7.320	4.011	EPSD	COSMIC	7.092	Loss
AGC_PKG_PRKG1_ST	P43694	GATA4	Q13976	PRKG1	S422	D425N	425	Missense	distal	3	no	7.320	7.232	EPSD	COSMIC;GDSC	7.092	Down-regulation
AGC_PKG_PRKG1_ST	P43694	GATA4	Q13976	PRKG1	S422	Q424K	424	Missense	proximal	2	no	7.320	7.312	EPSD	COSMIC	7.092	Down-regulation
AGC_PKG_PRKG1_ST	P43694	GATA4	Q13976	PRKG1	S422	D425A	425	Missense	distal	3	no	7.320	7.141	EPSD	COSMIC	7.092	Down-regulation
AGC_PKG_PRKG1_ST	P61586	RHOA	Q13976	PRKG1	T19	C16R	16	Missense	distal	-3	no	1.515	8.537	EPSD	COSMIC	7.092	Gain
AGC_PKG_PRKG1_ST	P61586	RHOA	Q13976	PRKG1	S73	R70K	70	Missense	distal	-3	no	7.618	5.260	EPSD	COSMIC;GDSC;CCLE	7.092	Loss
AGC_PKG_PRKG1_ST	P61586	RHOA	Q13976	PRKG1	S73	S73Y	73	Missense	central	0	yes	7.618	0.000	EPSD	COSMIC	7.092	Loss
AGC_PKG_PRKG1_ST	P61586	RHOA	Q13976	PRKG1	S73	I80M	80	Missense	distal	7	no	7.618	7.748	EPSD	COSMIC	7.092	Up-regulation
AGC_PKG_PRKG1_ST	P61586	RHOA	Q13976	PRKG1	S73	P75L	75	Missense	proximal	2	no	7.618	7.574	EPSD	COSMIC	7.092	Down-regulation
AGC_PKG_PRKG1_ST	P61586	RHOA	Q13976	PRKG1	S73	R68L	68	Missense	distal	-5	no	7.618	7.995	EPSD	COSMIC	7.092	Up-regulation
AGC_PKG_PRKG1_ST	P61586	RHOA	Q13976	PRKG1	S73	D76H	76	Missense	distal	3	no	7.618	7.505	EPSD	COSMIC	7.092	Down-regulation
AGC_PKG_PRKG1_ST	P61586	RHOA	Q13976	PRKG1	S73	D78V	78	Missense	distal	5	no	7.618	7.622	EPSD	COSMIC	7.092	Up-regulation
AGC_PKG_PRKG1_ST	P61586	RHOA	Q13976	PRKG1	S73	P75T	75	Missense	proximal	2	no	7.618	7.685	EPSD	COSMIC	7.092	Up-regulation
AGC_PKG_PRKG1_ST	P61586	RHOA	Q13976	PRKG1	S73	R68H	68	Missense	distal	-5	no	7.618	7.820	EPSD	COSMIC	7.092	Up-regulation
AGC_PKG_PRKG1_ST	P61586	RHOA	Q13976	PRKG1	S73	L72P	72	Missense	proximal	-1	no	7.618	7.716	EPSD	COSMIC	7.092	Up-regulation
AGC_PKG_PRKG1_ST	P61586	RHOA	Q13976	PRKG1	S188	K185N	185	Missense	distal	-3	no	11.288	6.742	PhosphoSitePlus	COSMIC	7.092	Loss
AGC_PKG_PRKG1_ST	P61586	RHOA	Q13976	PRKG1	S188	G189V	189	Missense	proximal	1	no	11.288	11.142	PhosphoSitePlus	COSMIC	7.092	Down-regulation
AGC_PKG_PRKG1_ST	P61586	RHOA	Q13976	PRKG1	S188	K185T	185	Missense	distal	-3	no	11.288	8.481	PhosphoSitePlus	COSMIC	7.092	Down-regulation
AGC_PKG_PRKG1_ST	P61586	RHOA	Q13976	PRKG1	S188	G184E	184	Missense	distal	-4	no	11.288	11.006	PhosphoSitePlus	COSMIC	7.092	Down-regulation
AGC_PKG_PRKG1_ST	P10644	PRKAR1A	Q13976	PRKG1	T73	R74H	74	Missense	proximal	1	no	7.426	7.090	EPSD	COSMIC;GDSC	7.092	Loss
AGC_PKG_PRKG1_ST	P10644	PRKAR1A	Q13976	PRKG1	T73	Q66L	66	Missense	distal	-7	no	7.426	6.087	EPSD	COSMIC	7.092	Loss
AGC_PKG_PRKG1_ST	P10644	PRKAR1A	Q13976	PRKG1	S77	I82M	82	Missense	distal	5	no	11.169	11.263	EPSD	COSMIC	7.092	Up-regulation
AGC_PKG_PRKG1_ST	P10644	PRKAR1A	Q13976	PRKG1	S77	E81K	81	Missense	distal	4	no	11.169	11.054	EPSD	COSMIC	7.092	Down-regulation
AGC_PKG_PRKG1_ST	P10644	PRKAR1A	Q13976	PRKG1	S77	S83P	83	Missense	distal	6	no	11.169	11.404	EPSD	COSMIC	7.092	Up-regulation
AGC_PKG_PRKG1_ST	P10644	PRKAR1A	Q13976	PRKG1	S77	R74H	74	Missense	distal	-3	no	11.169	5.102	EPSD	COSMIC;GDSC	7.092	Loss
AGC_PKG_PRKG1_ST	P10644	PRKAR1A	Q13976	PRKG1	S77	E81Q	81	Missense	distal	4	no	11.169	11.072	EPSD	COSMIC;GDSC;CCLE	7.092	Down-regulation
AGC_PKG_PRKG1_ST	P10644	PRKAR1A	Q13976	PRKG1	S101	Y105N	105	Missense	distal	4	no	8.702	8.634	PhosphoSitePlus	COSMIC	7.092	Down-regulation
AGC_PKG_PRKG1_ST	P10644	PRKAR1A	Q13976	PRKG1	S101	V104I	104	Missense	distal	3	no	8.702	8.796	PhosphoSitePlus	COSMIC	7.092	Up-regulation
AGC_PKG_PRKG1_ST	P10644	PRKAR1A	Q13976	PRKG1	S101	I100V	100	Missense	proximal	-1	no	8.702	8.789	PhosphoSitePlus	COSMIC	7.092	Up-regulation
AGC_PKG_PRKG1_ST	P10644	PRKAR1A	Q13976	PRKG1	S101	E107V	107	Missense	distal	6	no	8.702	8.725	PhosphoSitePlus	COSMIC	7.092	Up-regulation
AGC_PKG_PRKG1_ST	P10644	PRKAR1A	Q13976	PRKG1	S307	R306W	306	Missense	proximal	-1	no	9.166	8.909	EPSD	COSMIC	7.092	Down-regulation
AGC_PKG_PRKG1_ST	P10644	PRKAR1A	Q13976	PRKG1	S307	V313F	313	Missense	distal	6	no	9.166	9.130	EPSD	COSMIC	7.092	Down-regulation
AGC_PKG_PRKG1_ST	P10644	PRKAR1A	Q13976	PRKG1	S307	R305H	305	Missense	proximal	-2	no	9.166	4.909	EPSD	COSMIC	7.092	Loss
AGC_PKG_PRKG1_ST	P10644	PRKAR1A	Q13976	PRKG1	S307	R306G	306	Missense	proximal	-1	no	9.166	9.002	EPSD	COSMIC	7.092	Down-regulation
AGC_PKG_PRKG1_ST	P10644	PRKAR1A	Q13976	PRKG1	T338	R333H	333	Missense	distal	-5	no	7.694	7.896	EPSD	COSMIC	7.092	Up-regulation
AGC_PKG_PRKG1_ST	P10644	PRKAR1A	Q13976	PRKG1	T338	R333C	333	Missense	distal	-5	no	7.694	7.950	EPSD	COSMIC	7.092	Up-regulation
AGC_PKG_PRKG1_ST	P10644	PRKAR1A	Q13976	PRKG1	T338	R342C	342	Missense	distal	4	no	7.694	7.853	EPSD	COSMIC	7.092	Up-regulation
AGC_PKG_PRKG1_ST	P10644	PRKAR1A	Q13976	PRKG1	T338	R333S	333	Missense	distal	-5	no	7.694	7.834	EPSD	COSMIC	7.092	Up-regulation
AGC_PKG_PRKG1_ST	P10644	PRKAR1A	Q13976	PRKG1	T338	V340A	340	Missense	proximal	2	no	7.694	7.778	EPSD	COSMIC	7.092	Up-regulation
AGC_PKG_PRKG1_ST	P10644	PRKAR1A	Q13976	PRKG1	T338	P334L	334	Missense	distal	-4	no	7.694	7.344	EPSD	COSMIC	7.092	Down-regulation
AGC_PKG_PRKG1_ST	P11831	SRF	Q13976	PRKG1	S16	A9T	9	Missense	distal	-7	no	9.131	9.076	EPSD	COSMIC	7.092	Down-regulation
AGC_PKG_PRKG1_ST	P11831	SRF	Q13976	PRKG1	T159	R157C	157	Missense	proximal	-2	no	9.295	4.566	PhosphoSitePlus	COSMIC	7.092	Loss
AGC_PKG_PRKG1_ST	P11831	SRF	Q13976	PRKG1	T160	R157C	157	Missense	distal	-3	no	8.156	1.134	EPSD	COSMIC	7.092	Loss
AGC_PKG_PRKG1_ST	P11831	SRF	Q13976	PRKG1	S237	T244P	244	Missense	distal	7	no	10.171	10.080	EPSD	COSMIC;GDSC;CCLE	7.092	Down-regulation
AGC_PKG_PRKG1_ST	P21731	TBXA2R	Q13976	PRKG1	S324	R322G	322	Missense	proximal	-2	no	11.181	7.693	EPSD	COSMIC;CCLE	7.092	Down-regulation
AGC_PKG_PRKG1_ST	P21731	TBXA2R	Q13976	PRKG1	S329	R322G	322	Missense	distal	-7	no	11.239	10.089	EPSD	COSMIC;CCLE	7.092	Down-regulation
AGC_PKG_PRKG1_ST	P35520	CBS	Q13976	PRKG1	T193	D198G	198	Missense	distal	5	no	9.520	9.535	EPSD	COSMIC	7.092	Up-regulation
AGC_PKG_PRKG1_ST	P35520	CBS	Q13976	PRKG1	T193	P200Q	200	Missense	distal	7	no	9.520	9.619	EPSD	COSMIC	7.092	Up-regulation
AGC_PKG_PRKG1_ST	P35520	CBS	Q13976	PRKG1	T193	D198E	198	Missense	distal	5	no	9.520	9.530	EPSD	COSMIC	7.092	Up-regulation
AGC_PKG_PRKG1_ST	P35520	CBS	Q13976	PRKG1	T193	D198N	198	Missense	distal	5	no	9.520	9.555	EPSD	COSMIC	7.092	Up-regulation
AGC_PKG_PRKG1_ST	P35520	CBS	Q13976	PRKG1	S199	D198G	198	Missense	proximal	-1	no	8.007	8.105	EPSD	COSMIC	7.092	Up-regulation
AGC_PKG_PRKG1_ST	P35520	CBS	Q13976	PRKG1	S199	E201K	201	Missense	proximal	2	no	8.007	8.057	EPSD	COSMIC	7.092	Up-regulation
AGC_PKG_PRKG1_ST	P35520	CBS	Q13976	PRKG1	S199	P200Q	200	Missense	proximal	1	no	8.007	8.279	EPSD	COSMIC	7.092	Up-regulation
AGC_PKG_PRKG1_ST	P35520	CBS	Q13976	PRKG1	S199	D198E	198	Missense	proximal	-1	no	8.007	8.049	EPSD	COSMIC	7.092	Up-regulation
AGC_PKG_PRKG1_ST	P35520	CBS	Q13976	PRKG1	S199	D198N	198	Missense	proximal	-1	no	8.007	8.084	EPSD	COSMIC	7.092	Up-regulation
AGC_PKG_PRKG1_ST	P35520	CBS	Q13976	PRKG1	S202	D198G	198	Missense	distal	-4	no	7.017	7.445	EPSD	COSMIC	7.092	Gain
AGC_PKG_PRKG1_ST	P35520	CBS	Q13976	PRKG1	S202	E201K	201	Missense	proximal	-1	no	7.017	7.178	EPSD	COSMIC	7.092	Gain
AGC_PKG_PRKG1_ST	P35520	CBS	Q13976	PRKG1	S202	P200Q	200	Missense	proximal	-2	no	7.017	7.811	EPSD	COSMIC	7.092	Gain
AGC_PKG_PRKG1_ST	P35520	CBS	Q13976	PRKG1	S202	D198E	198	Missense	distal	-4	no	7.017	7.163	EPSD	COSMIC	7.092	Gain
AGC_PKG_PRKG1_ST	P35520	CBS	Q13976	PRKG1	S202	D198N	198	Missense	distal	-4	no	7.017	7.286	EPSD	COSMIC	7.092	Gain
AGC_PKG_PRKG1_ST	P35520	CBS	Q13976	PRKG1	S227	D234E	234	Missense	distal	7	no	8.362	8.376	PhosphoSitePlus;EPSD	COSMIC	7.092	Up-regulation
AGC_PKG_PRKG1_ST	Q9Y210	TRPC6	Q13976	PRKG1	S4	S2R	2	Missense	proximal	-2	no	4.564	7.972	EPSD	COSMIC	7.092	Gain
AGC_PKG_PRKG1_ST	Q9Y210	TRPC6	Q13976	PRKG1	S13	A19G	19	Missense	distal	6	no	13.571	13.682	EPSD	COSMIC;CCLE	7.092	Up-regulation
AGC_PKG_PRKG1_ST	Q9Y210	TRPC6	Q13976	PRKG1	S13	G8V	8	Missense	distal	-5	no	13.571	13.608	EPSD	COSMIC	7.092	Up-regulation
AGC_PKG_PRKG1_ST	Q9Y210	TRPC6	Q13976	PRKG1	S14	A19G	19	Missense	distal	5	no	12.504	12.464	EPSD	COSMIC;CCLE	7.092	Down-regulation
AGC_PKG_PRKG1_ST	Q9Y210	TRPC6	Q13976	PRKG1	S14	G8V	8	Missense	distal	-6	no	12.504	12.341	EPSD	COSMIC	7.092	Down-regulation
AGC_PKG_PRKG1_ST	Q9Y210	TRPC6	Q13976	PRKG1	T70	H66L	66	Missense	distal	-4	no	12.250	11.763	PhosphoSitePlus;EPSD	COSMIC	7.092	Down-regulation
AGC_PKG_PRKG1_ST	Q9Y210	TRPC6	Q13976	PRKG1	S94	R91H	91	Missense	distal	-3	no	9.035	2.968	EPSD	COSMIC	7.092	Loss
AGC_PKG_PRKG1_ST	Q9Y210	TRPC6	Q13976	PRKG1	S94	R91S	91	Missense	distal	-3	no	9.035	3.547	EPSD	COSMIC	7.092	Loss
AGC_PKG_PRKG1_ST	Q9Y210	TRPC6	Q13976	PRKG1	S94	L95Q	95	Missense	proximal	1	no	9.035	9.538	EPSD	COSMIC;CCLE	7.092	Up-regulation
AGC_PKG_PRKG1_ST	Q9Y210	TRPC6	Q13976	PRKG1	S322	Y318C	318	Missense	distal	-4	no	9.394	9.343	EPSD;PhosphoSitePlus	COSMIC	7.092	Down-regulation
AGC_PKG_PRKG1_ST	Q9Y210	TRPC6	Q13976	PRKG1	S322	D327A	327	Missense	distal	5	no	9.394	9.447	EPSD;PhosphoSitePlus	COSMIC	7.092	Up-regulation
AGC_PKG_PRKG1_ST	Q9Y210	TRPC6	Q13976	PRKG1	S322	K326T	326	Missense	distal	4	no	9.394	9.411	EPSD;PhosphoSitePlus	COSMIC	7.092	Up-regulation
AGC_PKG_PRKG1_ST	Q9Y210	TRPC6	Q13976	PRKG1	S322	K326Q	326	Missense	distal	4	no	9.394	9.412	EPSD;PhosphoSitePlus	COSMIC	7.092	Up-regulation
AGC_PKG_PRKG1_ST	Q9Y210	TRPC6	Q13976	PRKG1	S785	K781R	781	Missense	distal	-4	no	6.984	7.288	EPSD	COSMIC;GDSC	7.092	Gain
AGC_PKG_PRKG1_ST	Q9Y210	TRPC6	Q13976	PRKG1	S836	G830V	830	Missense	distal	-6	no	8.089	7.927	EPSD	COSMIC	7.092	Down-regulation
AGC_PKG_PRKG1_ST	P35367	HRH1	Q13976	PRKG1	T142	L149M	149	Missense	distal	7	no	7.063	7.214	EPSD	COSMIC	7.092	Gain
AGC_PKG_PRKG1_ST	P35367	HRH1	Q13976	PRKG1	S271	G269R	269	Missense	proximal	-2	no	4.808	8.295	EPSD	COSMIC	7.092	Gain
AGC_PKG_PRKG1_ST	P35367	HRH1	Q13976	PRKG1	S277	G270E	270	Missense	distal	-7	no	8.189	7.871	EPSD	COSMIC	7.092	Down-regulation
AGC_PKG_PRKG1_ST	P35367	HRH1	Q13976	PRKG1	S277	E282K	282	Missense	distal	5	no	8.189	8.252	EPSD	COSMIC	7.092	Up-regulation
AGC_PKG_PRKG1_ST	P35367	HRH1	Q13976	PRKG1	S277	M283I	283	Missense	distal	6	no	8.189	8.467	EPSD	COSMIC	7.092	Up-regulation
AGC_PKG_PRKG1_ST	P35367	HRH1	Q13976	PRKG1	S285	E282K	282	Missense	distal	-3	no	4.969	9.552	EPSD	COSMIC	7.092	Gain
AGC_PKG_PRKG1_ST	P35367	HRH1	Q13976	PRKG1	S363	R360Q	360	Missense	distal	-3	no	10.249	6.414	EPSD	COSMIC	7.092	Loss
AGC_PKG_PRKG1_ST	P35367	HRH1	Q13976	PRKG1	S363	T369R	369	Missense	distal	6	no	10.249	10.137	EPSD	COSMIC	7.092	Down-regulation
AGC_PKG_PRKG1_ST	P35367	HRH1	Q13976	PRKG1	S363	T367A	367	Missense	distal	4	no	10.249	10.246	EPSD	COSMIC	7.092	Down-regulation
AGC_PKG_PRKG1_ST	P35367	HRH1	Q13976	PRKG1	S380	G383V	383	Missense	distal	3	no	9.236	9.301	EPSD	COSMIC	7.092	Up-regulation
AGC_PKG_PRKG1_ST	P35367	HRH1	Q13976	PRKG1	S380	D385E	385	Missense	distal	5	no	9.236	9.246	EPSD	COSMIC	7.092	Up-regulation
AGC_PKG_PRKG1_ST	P35367	HRH1	Q13976	PRKG1	S396	S396P	396	Missense	central	0	yes	8.063	0.000	EPSD;PhosphoSitePlus	COSMIC	7.092	Loss
AGC_PKG_PRKG1_ST	P35367	HRH1	Q13976	PRKG1	S396	S403F	403	Missense	distal	7	no	8.063	7.988	EPSD;PhosphoSitePlus	COSMIC	7.092	Down-regulation
AGC_PKG_PRKG1_ST	P35367	HRH1	Q13976	PRKG1	S396	R395S	395	Missense	proximal	-1	no	8.063	7.962	EPSD;PhosphoSitePlus	COSMIC	7.092	Down-regulation
AGC_PKG_PRKG1_ST	P35367	HRH1	Q13976	PRKG1	S396	R395L	395	Missense	proximal	-1	no	8.063	7.761	EPSD;PhosphoSitePlus	COSMIC	7.092	Down-regulation
AGC_PKG_PRKG1_ST	P35367	HRH1	Q13976	PRKG1	S398	G404R	404	Missense	distal	6	no	9.845	9.629	PhosphoSitePlus;EPSD	COSMIC	7.092	Down-regulation
AGC_PKG_PRKG1_ST	P35367	HRH1	Q13976	PRKG1	S398	S396P	396	Missense	proximal	-2	no	9.845	9.494	PhosphoSitePlus;EPSD	COSMIC	7.092	Down-regulation
AGC_PKG_PRKG1_ST	P35367	HRH1	Q13976	PRKG1	S398	S403F	403	Missense	distal	5	no	9.845	9.797	PhosphoSitePlus;EPSD	COSMIC	7.092	Down-regulation
AGC_PKG_PRKG1_ST	P35367	HRH1	Q13976	PRKG1	S398	R395S	395	Missense	distal	-3	no	9.845	4.356	PhosphoSitePlus;EPSD	COSMIC	7.092	Loss
AGC_PKG_PRKG1_ST	P35367	HRH1	Q13976	PRKG1	S398	R395L	395	Missense	distal	-3	no	9.845	2.700	PhosphoSitePlus;EPSD	COSMIC	7.092	Loss
AGC_PKG_PRKG1_ST	Q9NS28	RGS18	Q13976	PRKG1	S64	R65I	65	Missense	proximal	1	no	8.410	7.770	EPSD	COSMIC	7.092	Down-regulation
AGC_PKG_PRKG1_ST	Q9NS28	RGS18	Q13976	PRKG1	S64	D60G	60	Missense	distal	-4	no	8.410	8.838	EPSD	COSMIC	7.092	Up-regulation
AGC_PKG_PRKG1_ST	Q9NS28	RGS18	Q13976	PRKG1	S64	H58Y	58	Missense	distal	-6	no	8.410	8.274	EPSD	COSMIC	7.092	Down-regulation
AGC_PKG_PRKG1_ST	Q9NS28	RGS18	Q13976	PRKG1	S76	P77T	77	Missense	proximal	1	no	6.984	7.195	EPSD	COSMIC	7.092	Gain
AGC_PKG_PRKG1_ST	Q9NS28	RGS18	Q13976	PRKG1	S76	E72K	72	Missense	distal	-4	no	6.984	7.644	EPSD	COSMIC	7.092	Gain
AGC_PKG_PRKG1_ST	Q9NS28	RGS18	Q13976	PRKG1	S216	S216A	216	Missense	central	0	yes	13.647	0.000	PhosphoSitePlus	COSMIC	7.092	Loss
AGC_PKG_PRKG1_ST	Q9NS28	RGS18	Q13976	PRKG1	S216	R214I	214	Missense	proximal	-2	no	13.647	7.641	PhosphoSitePlus	COSMIC	7.092	Down-regulation
AGC_PKG_PRKG1_ST	Q9NS28	RGS18	Q13976	PRKG1	S216	R214G	214	Missense	proximal	-2	no	13.647	10.159	PhosphoSitePlus	COSMIC	7.092	Down-regulation
AGC_PKG_PRKG1_ST	Q9NS28	RGS18	Q13976	PRKG1	S216	P209S	209	Missense	distal	-7	no	13.647	14.414	PhosphoSitePlus	COSMIC	7.092	Up-regulation
AGC_PKG_PRKG1_ST	Q9NS28	RGS18	Q13976	PRKG1	S218	S216A	216	Missense	proximal	-2	no	12.201	12.153	EPSD	COSMIC	7.092	Down-regulation
AGC_PKG_PRKG1_ST	Q9NS28	RGS18	Q13976	PRKG1	S218	R214I	214	Missense	distal	-4	no	12.201	10.892	EPSD	COSMIC	7.092	Down-regulation
AGC_PKG_PRKG1_ST	Q9NS28	RGS18	Q13976	PRKG1	S218	R214G	214	Missense	distal	-4	no	12.201	11.518	EPSD	COSMIC	7.092	Down-regulation
AGC_PKG_PRKG1_ST	Q9NS28	RGS18	Q13976	PRKG1	T220	S216A	216	Missense	distal	-4	no	8.743	8.739	EPSD	COSMIC	7.092	Down-regulation
AGC_PKG_PRKG1_ST	Q9NS28	RGS18	Q13976	PRKG1	T220	R214I	214	Missense	distal	-6	no	8.743	7.810	EPSD	COSMIC	7.092	Down-regulation
AGC_PKG_PRKG1_ST	Q9NS28	RGS18	Q13976	PRKG1	T220	R214G	214	Missense	distal	-6	no	8.743	8.228	EPSD	COSMIC	7.092	Down-regulation
AGC_PKG_PRKG1_ST	Q9Y613	FHOD1	Q13976	PRKG1	S357	E359K	359	Missense	proximal	2	no	15.265	15.316	EPSD	COSMIC	7.092	Up-regulation
AGC_PKG_PRKG1_ST	Q9Y613	FHOD1	Q13976	PRKG1	S358	E359K	359	Missense	proximal	1	no	7.757	8.063	EPSD	COSMIC	7.092	Up-regulation
AGC_PKG_PRKG1_ST	Q9Y613	FHOD1	Q13976	PRKG1	S364	G371R	371	Missense	distal	7	no	8.240	8.352	EPSD	COSMIC	7.092	Up-regulation
AGC_PKG_PRKG1_ST	Q9Y613	FHOD1	Q13976	PRKG1	S364	S367Y	367	Missense	distal	3	no	8.240	8.431	EPSD	COSMIC	7.092	Up-regulation
AGC_PKG_PRKG1_ST	Q9Y613	FHOD1	Q13976	PRKG1	S364	E359K	359	Missense	distal	-5	no	8.240	8.059	EPSD	COSMIC	7.092	Down-regulation
AGC_PKG_PRKG1_ST	Q9Y613	FHOD1	Q13976	PRKG1	S367	G371R	371	Missense	distal	4	no	8.047	7.900	EPSD	COSMIC	7.092	Down-regulation
AGC_PKG_PRKG1_ST	Q9Y613	FHOD1	Q13976	PRKG1	S367	S367Y	367	Missense	central	0	yes	8.047	0.000	EPSD	COSMIC	7.092	Loss
AGC_PKG_PRKG1_ST	Q9Y613	FHOD1	Q13976	PRKG1	T465	L466F	466	Missense	proximal	1	no	7.320	7.574	EPSD	COSMIC;GDSC	7.092	Up-regulation
AGC_PKG_PRKG1_ST	Q9Y613	FHOD1	Q13976	PRKG1	S540	R535H	535	Missense	distal	-5	no	8.772	8.974	EPSD	COSMIC	7.092	Up-regulation
AGC_PKG_PRKG1_ST	Q9Y613	FHOD1	Q13976	PRKG1	S540	P533L	533	Missense	distal	-7	no	8.772	8.156	EPSD	COSMIC	7.092	Down-regulation
AGC_PKG_PRKG1_ST	Q9Y613	FHOD1	Q13976	PRKG1	S540	F546S	546	Missense	distal	6	no	8.772	8.580	EPSD	COSMIC	7.092	Down-regulation
AGC_PKG_PRKG1_ST	Q9Y613	FHOD1	Q13976	PRKG1	S874	R871Q	871	Missense	distal	-3	no	8.367	4.532	EPSD	COSMIC	7.092	Loss
AGC_PKG_PRKG1_ST	Q9Y613	FHOD1	Q13976	PRKG1	T1016	R1013H	1013	Missense	distal	-3	no	8.271	2.203	EPSD	COSMIC	7.092	Loss
AGC_PKG_PRKG1_ST	Q9Y613	FHOD1	Q13976	PRKG1	T1016	E1017K	1017	Missense	proximal	1	no	8.271	8.577	EPSD	COSMIC	7.092	Up-regulation
AGC_PKG_PRKG1_ST	Q9Y613	FHOD1	Q13976	PRKG1	T1016	R1013C	1013	Missense	distal	-3	no	8.271	1.249	EPSD	COSMIC	7.092	Loss
AGC_PKG_PRKG1_ST	Q9Y613	FHOD1	Q13976	PRKG1	T1016	E1019Q	1019	Missense	distal	3	no	8.271	8.087	EPSD	COSMIC	7.092	Down-regulation
AGC_PKG_PRKG1_ST	Q9Y613	FHOD1	Q13976	PRKG1	T1016	E1019D	1019	Missense	distal	3	no	8.271	8.285	EPSD	COSMIC	7.092	Up-regulation
AGC_PKG_PRKG1_ST	Q9Y613	FHOD1	Q13976	PRKG1	S1131	G1133S	1133	Missense	proximal	2	no	11.398	11.468	PhosphoSitePlus	COSMIC	7.092	Up-regulation
AGC_PKG_PRKG1_ST	Q9Y613	FHOD1	Q13976	PRKG1	S1137	G1133S	1133	Missense	distal	-4	no	8.446	8.659	EPSD	COSMIC	7.092	Up-regulation
AGC_PKG_PRKG1_ST	Q9Y613	FHOD1	Q13976	PRKG1	S1137	R1140K	1140	Missense	distal	3	no	8.446	8.526	EPSD	COSMIC	7.092	Up-regulation
AGC_PKG_PRKG1_ST	P78347	GTF2I	Q13976	PRKG1	S103	E108K	108	Missense	distal	5	no	7.368	7.430	EPSD	COSMIC	7.092	Up-regulation
AGC_PKG_PRKG1_ST	P78347	GTF2I	Q13976	PRKG1	S146	V150M	150	Missense	distal	4	no	8.106	7.988	EPSD	COSMIC	7.092	Down-regulation
AGC_PKG_PRKG1_ST	P78347	GTF2I	Q13976	PRKG1	S412	R410C	410	Missense	proximal	-2	no	13.979	9.250	EPSD;PhosphoSitePlus	COSMIC	7.092	Down-regulation
AGC_PKG_PRKG1_ST	P78347	GTF2I	Q13976	PRKG1	S412	L419M	419	Missense	distal	7	no	13.979	14.130	EPSD;PhosphoSitePlus	COSMIC	7.092	Up-regulation
AGC_PKG_PRKG1_ST	P78347	GTF2I	Q13976	PRKG1	S412	S412L	412	Missense	central	0	yes	13.979	0.000	EPSD;PhosphoSitePlus	COSMIC	7.092	Loss
AGC_PKG_PRKG1_ST	P78347	GTF2I	Q13976	PRKG1	S517	R523S	523	Missense	distal	6	no	8.811	8.883	EPSD	COSMIC	7.092	Up-regulation
AGC_PKG_PRKG1_ST	P78347	GTF2I	Q13976	PRKG1	S517	R514I	514	Missense	distal	-3	no	8.811	0.304	EPSD	COSMIC	7.092	Loss
AGC_PKG_PRKG1_ST	P78347	GTF2I	Q13976	PRKG1	T622	T622A	622	Missense	central	0	yes	7.948	0.000	EPSD	COSMIC	7.092	Loss
AGC_PKG_PRKG1_ST	P78347	GTF2I	Q13976	PRKG1	S636	R634C	634	Missense	proximal	-2	no	7.184	2.456	EPSD	COSMIC	7.092	Loss
AGC_PKG_PRKG1_ST	P78347	GTF2I	Q13976	PRKG1	S636	R634H	634	Missense	proximal	-2	no	7.184	2.927	EPSD	COSMIC	7.092	Loss
AGC_PKG_PRKG1_ST	P78347	GTF2I	Q13976	PRKG1	S636	E630Q	630	Missense	distal	-6	no	7.184	7.533	EPSD	COSMIC	7.092	Up-regulation
AGC_PKG_PRKG1_ST	P78347	GTF2I	Q13976	PRKG1	S674	S668P	668	Missense	distal	-6	no	9.431	9.115	EPSD	COSMIC	7.092	Down-regulation
AGC_PKG_PRKG1_ST	P78347	GTF2I	Q13976	PRKG1	T705	T707I	707	Missense	proximal	2	no	8.609	8.513	EPSD	COSMIC	7.092	Down-regulation
AGC_PKG_PRKG1_ST	P78347	GTF2I	Q13976	PRKG1	T705	V712I	712	Missense	distal	7	no	8.609	8.555	EPSD	COSMIC	7.092	Down-regulation
AGC_PKG_PRKG1_ST	P78347	GTF2I	Q13976	PRKG1	S722	F721L	721	Missense	proximal	-1	no	8.298	8.190	EPSD	COSMIC	7.092	Down-regulation
AGC_PKG_PRKG1_ST	Q96D31	ORAI1	Q13976	PRKG1	S13	S13R	13	Missense	central	0	yes	8.488	0.000	EPSD	COSMIC	7.092	Loss
AGC_PKG_PRKG1_ST	Q96D31	ORAI1	Q13976	PRKG1	S34	G41R	41	Missense	distal	7	no	14.447	14.560	PhosphoSitePlus	COSMIC	7.092	Up-regulation
AGC_PKG_PRKG1_ST	Q14847	LASP1	Q13976	PRKG1	S61	A55T	55	Missense	distal	-6	no	7.442	7.403	EPSD	COSMIC	7.092	Down-regulation
AGC_PKG_PRKG1_ST	Q14847	LASP1	Q13976	PRKG1	S61	M64L	64	Missense	distal	3	no	7.442	7.775	EPSD	COSMIC	7.092	Up-regulation
AGC_PKG_PRKG1_ST	Q14847	LASP1	Q13976	PRKG1	S61	T63S	63	Missense	proximal	2	no	7.442	7.474	EPSD	COSMIC	7.092	Up-regulation
AGC_PKG_PRKG1_ST	Q14847	LASP1	Q13976	PRKG1	S61	M64T	64	Missense	distal	3	no	7.442	7.398	EPSD	COSMIC	7.092	Down-regulation
AGC_PKG_PRKG1_ST	Q14847	LASP1	Q13976	PRKG1	S99	D103E	103	Missense	distal	4	no	7.566	7.553	EPSD	COSMIC	7.092	Down-regulation
AGC_PKG_PRKG1_ST	Q14847	LASP1	Q13976	PRKG1	S99	S99I	99	Missense	central	0	yes	7.566	0.000	EPSD	COSMIC	7.092	Loss
AGC_PKG_PRKG1_ST	Q14847	LASP1	Q13976	PRKG1	S146	E140Q	140	Missense	distal	-6	no	12.899	13.247	PhosphoSitePlus	COSMIC	7.092	Up-regulation
AGC_PKG_PRKG1_ST	Q14847	LASP1	Q13976	PRKG1	S146	R153W	153	Missense	distal	7	no	12.899	12.745	PhosphoSitePlus	COSMIC;GDSC	7.092	Down-regulation
AGC_PKG_PRKG1_ST	Q14847	LASP1	Q13976	PRKG1	S146	R144L	144	Missense	proximal	-2	no	12.899	7.605	PhosphoSitePlus	COSMIC	7.092	Down-regulation
AGC_PKG_PRKG1_ST	Q14847	LASP1	Q13976	PRKG1	S146	G149D	149	Missense	distal	3	no	12.899	12.941	PhosphoSitePlus	COSMIC	7.092	Up-regulation
AGC_PKG_PRKG1_ST	Q96A00	PPP1R14A	Q13976	PRKG1	S16	A20T	20	Missense	distal	4	no	7.869	7.872	EPSD	COSMIC	7.092	Up-regulation
AGC_PKG_PRKG1_ST	Q96A00	PPP1R14A	Q13976	PRKG1	S16	P23A	23	Missense	distal	7	no	7.869	7.949	EPSD	COSMIC	7.092	Up-regulation
AGC_PKG_PRKG1_ST	Q96A00	PPP1R14A	Q13976	PRKG1	S128	P122L	122	Missense	distal	-6	no	8.666	8.355	EPSD	COSMIC	7.092	Down-regulation
AGC_PKG_PRKG1_ST	Q684P5	RAP1GAP2	Q13976	PRKG1	S7	R4S	4	Missense	distal	-3	no	11.498	6.010	PhosphoSitePlus	COSMIC	7.092	Loss
AGC_PKG_PRKG1_ST	Q684P5	RAP1GAP2	Q13976	PRKG1	S7	S9F	9	Missense	proximal	2	no	11.498	11.421	PhosphoSitePlus	COSMIC	7.092	Down-regulation
AGC_PKG_PRKG1_ST	Q684P5	RAP1GAP2	Q13976	PRKG1	S9	R4S	4	Missense	distal	-5	no	10.185	10.325	EPSD	COSMIC	7.092	Up-regulation
AGC_PKG_PRKG1_ST	Q684P5	RAP1GAP2	Q13976	PRKG1	S9	S9F	9	Missense	central	0	yes	10.185	0.000	EPSD	COSMIC	7.092	Loss
AGC_PKG_PRKG1_ST	Q684P5	RAP1GAP2	Q13976	PRKG1	S505	R504P	504	Missense	proximal	-1	no	9.649	9.444	EPSD	COSMIC	7.092	Down-regulation
AGC_PKG_PRKG1_ST	Q684P5	RAP1GAP2	Q13976	PRKG1	S505	R502H	502	Missense	distal	-3	no	9.649	3.582	EPSD	COSMIC;CCLE	7.092	Loss
AGC_PKG_PRKG1_ST	Q684P5	RAP1GAP2	Q13976	PRKG1	S505	R504C	504	Missense	proximal	-1	no	9.649	9.448	EPSD	COSMIC	7.092	Down-regulation
AGC_PKG_PRKG1_ST	Q684P5	RAP1GAP2	Q13976	PRKG1	S507	R504P	504	Missense	distal	-3	no	9.266	4.365	EPSD	COSMIC	7.092	Loss
AGC_PKG_PRKG1_ST	Q684P5	RAP1GAP2	Q13976	PRKG1	S507	R502H	502	Missense	distal	-5	no	9.266	9.469	EPSD	COSMIC;CCLE	7.092	Up-regulation
AGC_PKG_PRKG1_ST	Q684P5	RAP1GAP2	Q13976	PRKG1	S507	R504C	504	Missense	distal	-3	no	9.266	2.244	EPSD	COSMIC	7.092	Loss
AGC_PKG_PRKG1_ST	Q684P5	RAP1GAP2	Q13976	PRKG1	S518	S520N	520	Missense	proximal	2	no	9.982	9.918	EPSD	COSMIC	7.092	Down-regulation
AGC_PKG_PRKG1_ST	Q684P5	RAP1GAP2	Q13976	PRKG1	S520	S520N	520	Missense	central	0	yes	8.974	0.000	EPSD	COSMIC	7.092	Loss
AGC_PKG_PRKG1_ST	Q684P5	RAP1GAP2	Q13976	PRKG1	S556	R562W	562	Missense	distal	6	no	7.102	7.443	EPSD	COSMIC	7.092	Up-regulation
AGC_PKG_PRKG1_ST	Q684P5	RAP1GAP2	Q13976	PRKG1	S556	T551M	551	Missense	distal	-5	no	7.102	7.113	EPSD	COSMIC;CCLE	7.092	Up-regulation
AGC_PKG_PRKG1_ST	Q684P5	RAP1GAP2	Q13976	PRKG1	S556	T551K	551	Missense	distal	-5	no	7.102	7.045	EPSD	COSMIC	7.092	Loss
AGC_PKG_PRKG1_ST	Q684P5	RAP1GAP2	Q13976	PRKG1	S556	R563L	563	Missense	distal	7	no	7.102	6.896	EPSD	COSMIC	7.092	Loss
AGC_PKG_PRKG1_ST	Q684P5	RAP1GAP2	Q13976	PRKG1	S564	R562W	562	Missense	proximal	-2	no	13.411	8.081	EPSD	COSMIC	7.092	Down-regulation
AGC_PKG_PRKG1_ST	Q684P5	RAP1GAP2	Q13976	PRKG1	S564	R563L	563	Missense	proximal	-1	no	13.411	13.109	EPSD	COSMIC	7.092	Down-regulation
AGC_PKG_PRKG1_ST	Q684P5	RAP1GAP2	Q13976	PRKG1	S586	S589N	589	Missense	distal	3	no	7.714	7.829	EPSD	COSMIC;GDSC;CCLE	7.092	Up-regulation
AGC_PKG_PRKG1_ST	Q684P5	RAP1GAP2	Q13976	PRKG1	S586	R581Q	581	Missense	distal	-5	no	7.714	7.835	EPSD	COSMIC	7.092	Up-regulation
AGC_PKG_PRKG1_ST	Q684P5	RAP1GAP2	Q13976	PRKG1	S608	E606K	606	Missense	proximal	-2	no	3.869	7.392	EPSD	COSMIC	7.092	Gain
AGC_PKG_PRKG1_ST	Q684P5	RAP1GAP2	Q13976	PRKG1	S638	S640N	640	Missense	proximal	2	no	7.581	7.517	EPSD	COSMIC	7.092	Down-regulation
AGC_PKG_PRKG1_ST	Q684P5	RAP1GAP2	Q13976	PRKG1	S639	S640N	640	Missense	proximal	1	no	12.053	11.849	EPSD	COSMIC	7.092	Down-regulation
AGC_PKG_PRKG1_ST	Q684P5	RAP1GAP2	Q13976	PRKG1	T702	S700N	700	Missense	proximal	-2	no	7.846	6.833	EPSD	COSMIC	7.092	Loss
AGC_PKG_PRKG1_ST	Q8WZ42	TTN	Q13976	PRKG1	S79	G85E	85	Missense	distal	6	no	10.417	10.480	EPSD	COSMIC	7.092	Up-regulation
AGC_PKG_PRKG1_ST	Q8WZ42	TTN	Q13976	PRKG1	S112	R109G	109	Missense	distal	-3	no	9.072	4.482	EPSD	COSMIC	7.092	Loss
AGC_PKG_PRKG1_ST	Q8WZ42	TTN	Q13976	PRKG1	S112	G118E	118	Missense	distal	6	no	9.072	9.135	EPSD	COSMIC	7.092	Up-regulation
AGC_PKG_PRKG1_ST	Q8WZ42	TTN	Q13976	PRKG1	S112	Q108E	108	Missense	distal	-4	no	9.072	8.502	EPSD	COSMIC	7.092	Down-regulation
AGC_PKG_PRKG1_ST	Q8WZ42	TTN	Q13976	PRKG1	S112	Q111H	111	Missense	proximal	-1	no	9.072	8.989	EPSD	COSMIC	7.092	Down-regulation
AGC_PKG_PRKG1_ST	Q8WZ42	TTN	Q13976	PRKG1	T186	V182A	182	Missense	distal	-4	no	6.758	7.284	EPSD	COSMIC	7.092	Gain
AGC_PKG_PRKG1_ST	Q8WZ42	TTN	Q13976	PRKG1	S263	P259S	259	Missense	distal	-4	no	8.914	9.337	EPSD	COSMIC	7.092	Up-regulation
AGC_PKG_PRKG1_ST	Q8WZ42	TTN	Q13976	PRKG1	S265	P259S	259	Missense	distal	-6	no	8.050	8.365	EPSD	COSMIC	7.092	Up-regulation
AGC_PKG_PRKG1_ST	Q8WZ42	TTN	Q13976	PRKG1	T300	P303S	303	Missense	distal	3	no	8.818	8.568	EPSD	COSMIC	7.092	Down-regulation
AGC_PKG_PRKG1_ST	Q8WZ42	TTN	Q13976	PRKG1	T300	P303L	303	Missense	distal	3	no	8.818	8.936	EPSD	COSMIC;GDSC;CCLE	7.092	Up-regulation
AGC_PKG_PRKG1_ST	Q8WZ42	TTN	Q13976	PRKG1	T300	V296M	296	Missense	distal	-4	no	8.818	9.215	EPSD	COSMIC	7.092	Up-regulation
AGC_PKG_PRKG1_ST	Q8WZ42	TTN	Q13976	PRKG1	T300	R297G	297	Missense	distal	-3	no	8.818	4.227	EPSD	COSMIC	7.092	Loss
AGC_PKG_PRKG1_ST	Q8WZ42	TTN	Q13976	PRKG1	T300	V296L	296	Missense	distal	-4	no	8.818	8.575	EPSD	COSMIC	7.092	Down-regulation
AGC_PKG_PRKG1_ST	Q8WZ42	TTN	Q13976	PRKG1	T300	P303T	303	Missense	distal	3	no	8.818	8.560	EPSD	COSMIC	7.092	Down-regulation
AGC_PKG_PRKG1_ST	Q8WZ42	TTN	Q13976	PRKG1	S308	P303S	303	Missense	distal	-5	no	9.833	9.718	EPSD	COSMIC	7.092	Down-regulation
AGC_PKG_PRKG1_ST	Q8WZ42	TTN	Q13976	PRKG1	S308	P303L	303	Missense	distal	-5	no	9.833	9.954	EPSD	COSMIC;GDSC;CCLE	7.092	Up-regulation
AGC_PKG_PRKG1_ST	Q8WZ42	TTN	Q13976	PRKG1	S308	R312K	312	Missense	distal	4	no	9.833	9.874	EPSD	COSMIC	7.092	Up-regulation
AGC_PKG_PRKG1_ST	Q8WZ42	TTN	Q13976	PRKG1	S308	P303T	303	Missense	distal	-5	no	9.833	9.727	EPSD	COSMIC	7.092	Down-regulation
AGC_PKG_PRKG1_ST	Q8WZ42	TTN	Q13976	PRKG1	S314	V321L	321	Missense	distal	7	no	8.828	8.754	EPSD	COSMIC	7.092	Down-regulation
AGC_PKG_PRKG1_ST	Q8WZ42	TTN	Q13976	PRKG1	S314	R312K	312	Missense	proximal	-2	no	8.828	7.351	EPSD	COSMIC	7.092	Down-regulation
AGC_PKG_PRKG1_ST	Q8WZ42	TTN	Q13976	PRKG1	T330	V335M	335	Missense	distal	5	no	7.819	7.878	EPSD	COSMIC	7.092	Up-regulation
AGC_PKG_PRKG1_ST	Q8WZ42	TTN	Q13976	PRKG1	T330	T334A	334	Missense	distal	4	no	7.819	7.816	EPSD	COSMIC	7.092	Down-regulation
AGC_PKG_PRKG1_ST	Q8WZ42	TTN	Q13976	PRKG1	T330	L326I	326	Missense	distal	-4	no	7.819	7.753	EPSD	COSMIC	7.092	Down-regulation
AGC_PKG_PRKG1_ST	Q8WZ42	TTN	Q13976	PRKG1	T330	M327I	327	Missense	distal	-3	no	7.819	4.616	EPSD	COSMIC	7.092	Loss
AGC_PKG_PRKG1_ST	Q8WZ42	TTN	Q13976	PRKG1	S540	R538I	538	Missense	proximal	-2	no	8.164	2.159	EPSD	COSMIC	7.092	Loss
AGC_PKG_PRKG1_ST	Q8WZ42	TTN	Q13976	PRKG1	S540	Q535K	535	Missense	distal	-5	no	8.164	8.137	EPSD	COSMIC	7.092	Down-regulation
AGC_PKG_PRKG1_ST	Q8WZ42	TTN	Q13976	PRKG1	S540	R538K	538	Missense	proximal	-2	no	8.164	6.687	EPSD	COSMIC	7.092	Loss
AGC_PKG_PRKG1_ST	Q8WZ42	TTN	Q13976	PRKG1	S540	E542D	542	Missense	proximal	2	no	8.164	8.156	EPSD	COSMIC	7.092	Down-regulation
AGC_PKG_PRKG1_ST	Q8WZ42	TTN	Q13976	PRKG1	S540	K533I	533	Missense	distal	-7	no	8.164	6.620	EPSD	COSMIC;GDSC;CCLE	7.092	Loss
AGC_PKG_PRKG1_ST	Q8WZ42	TTN	Q13976	PRKG1	T559	E560K	560	Missense	proximal	1	no	6.893	7.200	EPSD	COSMIC	7.092	Gain
AGC_PKG_PRKG1_ST	Q8WZ42	TTN	Q13976	PRKG1	S742	I741M	741	Missense	proximal	-1	no	7.300	7.490	EPSD	COSMIC	7.092	Up-regulation
AGC_PKG_PRKG1_ST	Q8WZ42	TTN	Q13976	PRKG1	S742	S742L	742	Missense	central	0	yes	7.300	0.000	EPSD	COSMIC	7.092	Loss
AGC_PKG_PRKG1_ST	Q8WZ42	TTN	Q13976	PRKG1	S742	E748K	748	Missense	distal	6	no	7.300	7.082	EPSD	COSMIC;GDSC;CCLE	7.092	Loss
AGC_PKG_PRKG1_ST	Q8WZ42	TTN	Q13976	PRKG1	S755	H758L	758	Missense	distal	3	no	8.887	9.165	EPSD	COSMIC	7.092	Up-regulation
AGC_PKG_PRKG1_ST	Q8WZ42	TTN	Q13976	PRKG1	S755	E748K	748	Missense	distal	-7	no	8.887	9.888	EPSD	COSMIC;GDSC;CCLE	7.092	Up-regulation
AGC_PKG_PRKG1_ST	Q8WZ42	TTN	Q13976	PRKG1	S755	P750L	750	Missense	distal	-5	no	8.887	9.009	EPSD	COSMIC;GDSC;CCLE	7.092	Up-regulation
AGC_PKG_PRKG1_ST	Q8WZ42	TTN	Q13976	PRKG1	S755	A754S	754	Missense	proximal	-1	no	8.887	8.893	EPSD	COSMIC	7.092	Up-regulation
AGC_PKG_PRKG1_ST	Q8WZ42	TTN	Q13976	PRKG1	S755	E756G	756	Missense	proximal	1	no	8.887	8.959	EPSD	COSMIC	7.092	Up-regulation
AGC_PKG_PRKG1_ST	Q8WZ42	TTN	Q13976	PRKG1	S755	P757L	757	Missense	proximal	2	no	8.887	8.843	EPSD	COSMIC	7.092	Down-regulation
AGC_PKG_PRKG1_ST	Q8WZ42	TTN	Q13976	PRKG1	T795	E800K	800	Missense	distal	5	no	7.363	7.426	EPSD	COSMIC	7.092	Up-regulation
AGC_PKG_PRKG1_ST	Q8WZ42	TTN	Q13976	PRKG1	T795	K793T	793	Missense	proximal	-2	no	7.363	5.248	EPSD	COSMIC	7.092	Loss
AGC_PKG_PRKG1_ST	Q8WZ42	TTN	Q13976	PRKG1	T811	V818M	818	Missense	distal	7	no	7.914	7.990	EPSD	COSMIC	7.092	Up-regulation
AGC_PKG_PRKG1_ST	Q8WZ42	TTN	Q13976	PRKG1	T811	D806N	806	Missense	distal	-5	no	7.914	7.831	EPSD	COSMIC	7.092	Down-regulation
AGC_PKG_PRKG1_ST	Q8WZ42	TTN	Q13976	PRKG1	T811	P814H	814	Missense	distal	3	no	7.914	7.754	EPSD	COSMIC	7.092	Down-regulation
AGC_PKG_PRKG1_ST	Q8WZ42	TTN	Q13976	PRKG1	S813	V818M	818	Missense	distal	5	no	8.560	8.619	EPSD	COSMIC	7.092	Up-regulation
AGC_PKG_PRKG1_ST	Q8WZ42	TTN	Q13976	PRKG1	S813	D806N	806	Missense	distal	-7	no	8.560	9.015	EPSD	COSMIC	7.092	Up-regulation
AGC_PKG_PRKG1_ST	Q8WZ42	TTN	Q13976	PRKG1	S813	P814H	814	Missense	proximal	1	no	8.560	8.661	EPSD	COSMIC	7.092	Up-regulation
AGC_PKG_PRKG1_ST	Q8WZ42	TTN	Q13976	PRKG1	S847	K854R	854	Missense	distal	7	no	7.475	7.517	EPSD	COSMIC	7.092	Up-regulation
AGC_PKG_PRKG1_ST	Q8WZ42	TTN	Q13976	PRKG1	S847	K854M	854	Missense	distal	7	no	7.475	7.462	EPSD	COSMIC	7.092	Down-regulation
AGC_PKG_PRKG1_ST	Q8WZ42	TTN	Q13976	PRKG1	S847	T849S	849	Missense	proximal	2	no	7.475	7.506	EPSD	COSMIC	7.092	Up-regulation
AGC_PKG_PRKG1_ST	Q8WZ42	TTN	Q13976	PRKG1	S847	E845K	845	Missense	proximal	-2	no	7.475	10.997	EPSD	COSMIC	7.092	Up-regulation
AGC_PKG_PRKG1_ST	Q8WZ42	TTN	Q13976	PRKG1	S847	A848V	848	Missense	proximal	1	no	7.475	7.152	EPSD	COSMIC	7.092	Down-regulation
AGC_PKG_PRKG1_ST	Q8WZ42	TTN	Q13976	PRKG1	S851	K854R	854	Missense	distal	3	no	7.471	7.390	EPSD	COSMIC	7.092	Down-regulation
AGC_PKG_PRKG1_ST	Q8WZ42	TTN	Q13976	PRKG1	S851	K854M	854	Missense	distal	3	no	7.471	7.492	EPSD	COSMIC	7.092	Up-regulation
AGC_PKG_PRKG1_ST	Q8WZ42	TTN	Q13976	PRKG1	S851	T849S	849	Missense	proximal	-2	no	7.471	7.655	EPSD	COSMIC	7.092	Up-regulation
AGC_PKG_PRKG1_ST	Q8WZ42	TTN	Q13976	PRKG1	S851	E845K	845	Missense	distal	-6	no	7.471	7.951	EPSD	COSMIC	7.092	Up-regulation
AGC_PKG_PRKG1_ST	Q8WZ42	TTN	Q13976	PRKG1	S851	A848V	848	Missense	distal	-3	no	7.471	6.369	EPSD	COSMIC	7.092	Loss
AGC_PKG_PRKG1_ST	Q8WZ42	TTN	Q13976	PRKG1	S851	T856A	856	Missense	distal	5	no	7.471	7.461	EPSD	COSMIC	7.092	Down-regulation
AGC_PKG_PRKG1_ST	Q8WZ42	TTN	Q13976	PRKG1	S851	S858L	858	Missense	distal	7	no	7.471	7.304	EPSD	COSMIC	7.092	Down-regulation
AGC_PKG_PRKG1_ST	Q8WZ42	TTN	Q13976	PRKG1	T1233	V1234A	1234	Missense	proximal	1	no	7.062	7.385	EPSD	COSMIC	7.092	Gain
AGC_PKG_PRKG1_ST	Q8WZ42	TTN	Q13976	PRKG1	S1348	P1352L	1352	Missense	distal	4	no	7.863	7.963	EPSD	COSMIC	7.092	Up-regulation
AGC_PKG_PRKG1_ST	Q8WZ42	TTN	Q13976	PRKG1	S1348	V1353G	1353	Missense	distal	5	no	7.863	7.874	EPSD	COSMIC	7.092	Up-regulation
AGC_PKG_PRKG1_ST	Q8WZ42	TTN	Q13976	PRKG1	S1404	L1405P	1405	Missense	proximal	1	no	6.999	7.229	EPSD	COSMIC	7.092	Gain
AGC_PKG_PRKG1_ST	Q8WZ42	TTN	Q13976	PRKG1	S1404	R1408C	1408	Missense	distal	4	no	6.999	7.159	EPSD	COSMIC	7.092	Gain
AGC_PKG_PRKG1_ST	Q8WZ42	TTN	Q13976	PRKG1	S1406	L1405P	1405	Missense	proximal	-1	no	9.812	9.910	EPSD	COSMIC	7.092	Up-regulation
AGC_PKG_PRKG1_ST	Q8WZ42	TTN	Q13976	PRKG1	S1406	S1413F	1413	Missense	distal	7	no	9.812	9.737	EPSD	COSMIC	7.092	Down-regulation
AGC_PKG_PRKG1_ST	Q8WZ42	TTN	Q13976	PRKG1	S1406	R1408C	1408	Missense	proximal	2	no	9.812	9.744	EPSD	COSMIC	7.092	Down-regulation
AGC_PKG_PRKG1_ST	Q8WZ42	TTN	Q13976	PRKG1	S1411	R1416C	1416	Missense	distal	5	no	12.218	12.148	EPSD	COSMIC	7.092	Down-regulation
AGC_PKG_PRKG1_ST	Q8WZ42	TTN	Q13976	PRKG1	S1411	L1405P	1405	Missense	distal	-6	no	12.218	12.529	EPSD	COSMIC	7.092	Up-regulation
AGC_PKG_PRKG1_ST	Q8WZ42	TTN	Q13976	PRKG1	S1411	S1413F	1413	Missense	proximal	2	no	12.218	12.141	EPSD	COSMIC	7.092	Down-regulation
AGC_PKG_PRKG1_ST	Q8WZ42	TTN	Q13976	PRKG1	S1411	R1408C	1408	Missense	distal	-3	no	12.218	5.196	EPSD	COSMIC	7.092	Loss
AGC_PKG_PRKG1_ST	Q8WZ42	TTN	Q13976	PRKG1	S1423	R1416C	1416	Missense	distal	-7	no	9.899	8.471	EPSD	COSMIC	7.092	Down-regulation
AGC_PKG_PRKG1_ST	Q8WZ42	TTN	Q13976	PRKG1	S1423	P1429L	1429	Missense	distal	6	no	9.899	10.027	EPSD	COSMIC	7.092	Up-regulation
AGC_PKG_PRKG1_ST	Q8WZ42	TTN	Q13976	PRKG1	S1423	R1421W	1421	Missense	proximal	-2	no	9.899	4.569	EPSD	COSMIC	7.092	Loss
AGC_PKG_PRKG1_ST	Q8WZ42	TTN	Q13976	PRKG1	S1428	P1429L	1429	Missense	proximal	1	no	11.058	10.828	EPSD	COSMIC	7.092	Down-regulation
AGC_PKG_PRKG1_ST	Q8WZ42	TTN	Q13976	PRKG1	S1428	P1434S	1434	Missense	distal	6	no	11.058	10.822	EPSD	COSMIC;CCLE	7.092	Down-regulation
AGC_PKG_PRKG1_ST	Q8WZ42	TTN	Q13976	PRKG1	S1428	R1431Q	1431	Missense	distal	3	no	11.058	11.129	EPSD	COSMIC	7.092	Up-regulation
AGC_PKG_PRKG1_ST	Q8WZ42	TTN	Q13976	PRKG1	S1428	S1433P	1433	Missense	distal	5	no	11.058	10.986	EPSD	COSMIC	7.092	Down-regulation
AGC_PKG_PRKG1_ST	Q8WZ42	TTN	Q13976	PRKG1	S1428	R1421W	1421	Missense	distal	-7	no	11.058	9.293	EPSD	COSMIC	7.092	Down-regulation
AGC_PKG_PRKG1_ST	Q8WZ42	TTN	Q13976	PRKG1	S1433	P1429L	1429	Missense	distal	-4	no	9.496	9.146	EPSD	COSMIC	7.092	Down-regulation
AGC_PKG_PRKG1_ST	Q8WZ42	TTN	Q13976	PRKG1	S1433	P1434S	1434	Missense	proximal	1	no	9.496	9.758	EPSD	COSMIC;CCLE	7.092	Up-regulation
AGC_PKG_PRKG1_ST	Q8WZ42	TTN	Q13976	PRKG1	S1433	R1431Q	1431	Missense	proximal	-2	no	9.496	6.531	EPSD	COSMIC	7.092	Loss
AGC_PKG_PRKG1_ST	Q8WZ42	TTN	Q13976	PRKG1	S1433	S1433P	1433	Missense	central	0	yes	9.496	0.000	EPSD	COSMIC	7.092	Loss
AGC_PKG_PRKG1_ST	Q8WZ42	TTN	Q13976	PRKG1	S1438	P1434S	1434	Missense	distal	-4	no	9.145	9.568	EPSD	COSMIC;CCLE	7.092	Up-regulation
AGC_PKG_PRKG1_ST	Q8WZ42	TTN	Q13976	PRKG1	S1438	R1431Q	1431	Missense	distal	-7	no	9.145	8.469	EPSD	COSMIC	7.092	Down-regulation
AGC_PKG_PRKG1_ST	Q8WZ42	TTN	Q13976	PRKG1	S1438	S1433P	1433	Missense	distal	-5	no	9.145	9.260	EPSD	COSMIC	7.092	Up-regulation
AGC_PKG_PRKG1_ST	Q8WZ42	TTN	Q13976	PRKG1	S1539	I1541T	1541	Missense	proximal	2	no	8.148	8.244	EPSD	COSMIC	7.092	Up-regulation
AGC_PKG_PRKG1_ST	Q8WZ42	TTN	Q13976	PRKG1	S1539	I1544V	1544	Missense	distal	5	no	8.148	8.184	EPSD	COSMIC	7.092	Up-regulation
AGC_PKG_PRKG1_ST	Q8WZ42	TTN	Q13976	PRKG1	S1539	R1538K	1538	Missense	proximal	-1	no	8.148	8.089	EPSD	COSMIC	7.092	Down-regulation
AGC_PKG_PRKG1_ST	Q8WZ42	TTN	Q13976	PRKG1	S1539	G1537C	1537	Missense	proximal	-2	no	8.148	6.907	EPSD	COSMIC;CCLE	7.092	Loss
AGC_PKG_PRKG1_ST	Q8WZ42	TTN	Q13976	PRKG1	S1540	I1541T	1541	Missense	proximal	1	no	8.248	8.661	EPSD	COSMIC	7.092	Up-regulation
AGC_PKG_PRKG1_ST	Q8WZ42	TTN	Q13976	PRKG1	S1540	I1544V	1544	Missense	distal	4	no	8.248	8.186	EPSD	COSMIC	7.092	Down-regulation
AGC_PKG_PRKG1_ST	Q8WZ42	TTN	Q13976	PRKG1	S1540	R1538K	1538	Missense	proximal	-2	no	8.248	6.770	EPSD	COSMIC	7.092	Loss
AGC_PKG_PRKG1_ST	Q8WZ42	TTN	Q13976	PRKG1	S1540	G1537C	1537	Missense	distal	-3	no	8.248	5.816	EPSD	COSMIC;CCLE	7.092	Loss
AGC_PKG_PRKG1_ST	Q8WZ42	TTN	Q13976	PRKG1	S1571	E1569K	1569	Missense	proximal	-2	no	6.795	10.318	EPSD	COSMIC	7.092	Gain
AGC_PKG_PRKG1_ST	Q8WZ42	TTN	Q13976	PRKG1	T1710	L1714R	1714	Missense	distal	4	no	8.254	7.967	EPSD	COSMIC	7.092	Down-regulation
AGC_PKG_PRKG1_ST	Q8WZ42	TTN	Q13976	PRKG1	T1710	T1710N	1710	Missense	central	0	yes	8.254	0.000	EPSD	COSMIC	7.092	Loss
AGC_PKG_PRKG1_ST	Q8WZ42	TTN	Q13976	PRKG1	T1986	E1983K	1983	Missense	distal	-3	no	3.577	8.160	EPSD	COSMIC	7.092	Gain
AGC_PKG_PRKG1_ST	Q8WZ42	TTN	Q13976	PRKG1	S2086	I2084M	2084	Missense	proximal	-2	no	6.947	9.688	EPSD	COSMIC	7.092	Gain
AGC_PKG_PRKG1_ST	Q8WZ42	TTN	Q13976	PRKG1	S2441	R2439H	2439	Missense	proximal	-2	no	7.430	3.173	EPSD	COSMIC	7.092	Loss
AGC_PKG_PRKG1_ST	Q8WZ42	TTN	Q13976	PRKG1	S2623	G2620R	2620	Missense	distal	-3	no	5.894	10.484	EPSD	COSMIC	7.092	Gain
AGC_PKG_PRKG1_ST	Q8WZ42	TTN	Q13976	PRKG1	T3022	R3028L	3028	Missense	distal	6	no	7.854	8.290	EPSD	COSMIC	7.092	Up-regulation
AGC_PKG_PRKG1_ST	Q8WZ42	TTN	Q13976	PRKG1	T3022	M3016T	3016	Missense	distal	-6	no	7.854	7.886	EPSD	COSMIC	7.092	Up-regulation
AGC_PKG_PRKG1_ST	Q8WZ42	TTN	Q13976	PRKG1	T3022	R3028M	3028	Missense	distal	6	no	7.854	7.980	EPSD	COSMIC	7.092	Up-regulation
AGC_PKG_PRKG1_ST	Q8WZ42	TTN	Q13976	PRKG1	T3022	K3020N	3020	Missense	proximal	-2	no	7.854	4.911	EPSD	COSMIC	7.092	Loss
AGC_PKG_PRKG1_ST	Q8WZ42	TTN	Q13976	PRKG1	T3022	I3027V	3027	Missense	distal	5	no	7.854	7.890	EPSD	COSMIC	7.092	Up-regulation
AGC_PKG_PRKG1_ST	Q8WZ42	TTN	Q13976	PRKG1	S3122	R3120Q	3120	Missense	proximal	-2	no	7.720	4.756	EPSD	COSMIC	7.092	Loss
AGC_PKG_PRKG1_ST	Q8WZ42	TTN	Q13976	PRKG1	S3122	D3123H	3123	Missense	proximal	1	no	7.720	7.894	EPSD	COSMIC	7.092	Up-regulation
AGC_PKG_PRKG1_ST	Q8WZ42	TTN	Q13976	PRKG1	S3122	I3116M	3116	Missense	distal	-6	no	7.720	8.241	EPSD	COSMIC	7.092	Up-regulation
AGC_PKG_PRKG1_ST	Q8WZ42	TTN	Q13976	PRKG1	S3213	R3211C	3211	Missense	proximal	-2	no	7.889	3.161	EPSD	COSMIC	7.092	Loss
AGC_PKG_PRKG1_ST	Q8WZ42	TTN	Q13976	PRKG1	S3213	E3217A	3217	Missense	distal	4	no	7.889	7.789	EPSD	COSMIC;GDSC;CCLE	7.092	Down-regulation
AGC_PKG_PRKG1_ST	Q8WZ42	TTN	Q13976	PRKG1	S3213	G3216E	3216	Missense	distal	3	no	7.889	7.917	EPSD	COSMIC	7.092	Up-regulation
AGC_PKG_PRKG1_ST	Q8WZ42	TTN	Q13976	PRKG1	S3213	D3214N	3214	Missense	proximal	1	no	7.889	8.020	EPSD	COSMIC;GDSC;CCLE	7.092	Up-regulation
AGC_PKG_PRKG1_ST	Q8WZ42	TTN	Q13976	PRKG1	S3228	S3228F	3228	Missense	central	0	yes	7.664	0.000	EPSD	COSMIC	7.092	Loss
AGC_PKG_PRKG1_ST	Q8WZ42	TTN	Q13976	PRKG1	S3228	R3226K	3226	Missense	proximal	-2	no	7.664	6.186	EPSD	COSMIC	7.092	Loss
AGC_PKG_PRKG1_ST	Q8WZ42	TTN	Q13976	PRKG1	S3369	R3367W	3367	Missense	proximal	-2	no	9.084	3.754	EPSD	COSMIC	7.092	Loss
AGC_PKG_PRKG1_ST	Q8WZ42	TTN	Q13976	PRKG1	T3501	E3499K	3499	Missense	proximal	-2	no	4.605	8.128	EPSD	COSMIC	7.092	Gain
AGC_PKG_PRKG1_ST	Q8WZ42	TTN	Q13976	PRKG1	S3594	I3592N	3592	Missense	proximal	-2	no	6.134	7.719	EPSD	COSMIC	7.092	Gain
AGC_PKG_PRKG1_ST	Q8WZ42	TTN	Q13976	PRKG1	S3788	E3785K	3785	Missense	distal	-3	no	2.800	7.382	EPSD	COSMIC	7.092	Gain
AGC_PKG_PRKG1_ST	Q8WZ42	TTN	Q13976	PRKG1	S4065	R4058M	4058	Missense	distal	-7	no	7.354	6.466	EPSD	COSMIC	7.092	Loss
AGC_PKG_PRKG1_ST	Q8WZ42	TTN	Q13976	PRKG1	S4065	S4062F	4062	Missense	distal	-3	no	7.354	6.166	EPSD	COSMIC	7.092	Loss
AGC_PKG_PRKG1_ST	Q8WZ42	TTN	Q13976	PRKG1	T4184	G4181R	4181	Missense	distal	-3	no	3.816	8.406	EPSD	COSMIC	7.092	Gain
AGC_PKG_PRKG1_ST	Q8WZ42	TTN	Q13976	PRKG1	S4185	Q4187R	4187	Missense	proximal	2	no	8.004	8.011	PhosphoSitePlus;EPSD	COSMIC	7.092	Up-regulation
AGC_PKG_PRKG1_ST	Q8WZ42	TTN	Q13976	PRKG1	S4185	G4181E	4181	Missense	distal	-4	no	8.004	7.722	PhosphoSitePlus;EPSD	COSMIC	7.092	Down-regulation
AGC_PKG_PRKG1_ST	Q8WZ42	TTN	Q13976	PRKG1	S4185	G4181R	4181	Missense	distal	-4	no	8.004	8.687	PhosphoSitePlus;EPSD	COSMIC	7.092	Up-regulation
AGC_PKG_PRKG1_ST	Q8WZ42	TTN	Q13976	PRKG1	S4486	T4489A	4489	Missense	distal	3	no	9.991	10.023	EPSD	COSMIC;GDSC	7.092	Up-regulation
AGC_PKG_PRKG1_ST	Q8WZ42	TTN	Q13976	PRKG1	S4486	T4489M	4489	Missense	distal	3	no	9.991	10.035	EPSD	COSMIC;GDSC	7.092	Up-regulation
AGC_PKG_PRKG1_ST	Q8WZ42	TTN	Q13976	PRKG1	S4486	R4483K	4483	Missense	distal	-3	no	9.991	7.633	EPSD	COSMIC	7.092	Down-regulation
AGC_PKG_PRKG1_ST	Q8WZ42	TTN	Q13976	PRKG1	S4486	R4483G	4483	Missense	distal	-3	no	9.991	5.401	EPSD	COSMIC	7.092	Loss
AGC_PKG_PRKG1_ST	Q8WZ42	TTN	Q13976	PRKG1	S4651	E4648K	4648	Missense	distal	-3	no	4.954	9.537	EPSD	COSMIC	7.092	Gain
AGC_PKG_PRKG1_ST	Q8WZ42	TTN	Q13976	PRKG1	S4993	A4999E	4999	Missense	distal	6	no	7.630	7.804	EPSD	COSMIC	7.092	Up-regulation
AGC_PKG_PRKG1_ST	Q8WZ42	TTN	Q13976	PRKG1	S4993	K4988I	4988	Missense	distal	-5	no	7.630	7.903	EPSD	COSMIC	7.092	Up-regulation
AGC_PKG_PRKG1_ST	Q8WZ42	TTN	Q13976	PRKG1	S4993	V4998A	4998	Missense	distal	5	no	7.630	7.679	EPSD	COSMIC	7.092	Up-regulation
AGC_PKG_PRKG1_ST	Q8WZ42	TTN	Q13976	PRKG1	S4993	Q5000R	5000	Missense	distal	7	no	7.630	7.672	EPSD	COSMIC	7.092	Up-regulation
AGC_PKG_PRKG1_ST	Q8WZ42	TTN	Q13976	PRKG1	S4993	S4993G	4993	Missense	central	0	yes	7.630	0.000	EPSD	COSMIC	7.092	Loss
AGC_PKG_PRKG1_ST	Q8WZ42	TTN	Q13976	PRKG1	S5072	P5068T	5068	Missense	distal	-4	no	9.375	9.679	EPSD	COSMIC	7.092	Up-regulation
AGC_PKG_PRKG1_ST	Q8WZ42	TTN	Q13976	PRKG1	S5072	K5075Q	5075	Missense	distal	3	no	9.375	9.365	EPSD	COSMIC	7.092	Down-regulation
AGC_PKG_PRKG1_ST	Q8WZ42	TTN	Q13976	PRKG1	S5141	S5141L	5141	Missense	central	0	yes	8.350	0.000	EPSD	COSMIC	7.092	Loss
AGC_PKG_PRKG1_ST	Q8WZ42	TTN	Q13976	PRKG1	S5141	S5148L	5148	Missense	distal	7	no	8.350	8.183	EPSD	COSMIC	7.092	Down-regulation
AGC_PKG_PRKG1_ST	Q8WZ42	TTN	Q13976	PRKG1	S5141	V5144A	5144	Missense	distal	3	no	8.350	8.149	EPSD	COSMIC	7.092	Down-regulation
AGC_PKG_PRKG1_ST	Q8WZ42	TTN	Q13976	PRKG1	S5276	A5282S	5282	Missense	distal	6	no	7.352	7.320	EPSD	COSMIC	7.092	Down-regulation
AGC_PKG_PRKG1_ST	Q8WZ42	TTN	Q13976	PRKG1	S5276	K5272E	5272	Missense	distal	-4	no	7.352	6.692	EPSD	COSMIC	7.092	Loss
AGC_PKG_PRKG1_ST	Q8WZ42	TTN	Q13976	PRKG1	S5276	A5282T	5282	Missense	distal	6	no	7.352	7.360	EPSD	COSMIC	7.092	Up-regulation
AGC_PKG_PRKG1_ST	Q8WZ42	TTN	Q13976	PRKG1	S5276	S5276F	5276	Missense	central	0	yes	7.352	0.000	EPSD	COSMIC	7.092	Loss
AGC_PKG_PRKG1_ST	Q8WZ42	TTN	Q13976	PRKG1	S5276	M5275I	5275	Missense	proximal	-1	no	7.352	7.162	EPSD	COSMIC	7.092	Down-regulation
AGC_PKG_PRKG1_ST	Q8WZ42	TTN	Q13976	PRKG1	S5276	S5280G	5280	Missense	distal	4	no	7.352	7.463	EPSD	COSMIC	7.092	Up-regulation
AGC_PKG_PRKG1_ST	Q8WZ42	TTN	Q13976	PRKG1	S5421	S5421F	5421	Missense	central	0	yes	7.986	0.000	EPSD	COSMIC	7.092	Loss
AGC_PKG_PRKG1_ST	Q8WZ42	TTN	Q13976	PRKG1	S5421	S5414F	5414	Missense	distal	-7	no	7.986	7.341	EPSD	COSMIC	7.092	Down-regulation
AGC_PKG_PRKG1_ST	Q8WZ42	TTN	Q13976	PRKG1	S5421	L5425F	5425	Missense	distal	4	no	7.986	7.863	EPSD	COSMIC	7.092	Down-regulation
AGC_PKG_PRKG1_ST	Q8WZ42	TTN	Q13976	PRKG1	S5497	E5504K	5504	Missense	distal	7	no	9.293	9.377	EPSD	COSMIC	7.092	Up-regulation
AGC_PKG_PRKG1_ST	Q8WZ42	TTN	Q13976	PRKG1	S5497	V5502I	5502	Missense	distal	5	no	9.293	9.257	EPSD	COSMIC	7.092	Down-regulation
AGC_PKG_PRKG1_ST	Q8WZ42	TTN	Q13976	PRKG1	S5497	G5492E	5492	Missense	distal	-5	no	9.293	9.340	EPSD	COSMIC	7.092	Up-regulation
AGC_PKG_PRKG1_ST	Q8WZ42	TTN	Q13976	PRKG1	S5573	G5574R	5574	Missense	proximal	1	no	6.945	7.309	EPSD	COSMIC	7.092	Gain
AGC_PKG_PRKG1_ST	Q8WZ42	TTN	Q13976	PRKG1	T5577	G5574R	5574	Missense	distal	-3	no	3.423	8.014	EPSD	COSMIC	7.092	Gain
AGC_PKG_PRKG1_ST	Q8WZ42	TTN	Q13976	PRKG1	S5588	R5586Q	5586	Missense	proximal	-2	no	8.684	5.719	EPSD	COSMIC	7.092	Loss
AGC_PKG_PRKG1_ST	Q8WZ42	TTN	Q13976	PRKG1	S5588	G5585S	5585	Missense	distal	-3	no	8.684	7.786	EPSD	COSMIC	7.092	Down-regulation
AGC_PKG_PRKG1_ST	Q8WZ42	TTN	Q13976	PRKG1	S5588	D5583V	5583	Missense	distal	-5	no	8.684	8.633	EPSD	COSMIC;GDSC	7.092	Down-regulation
AGC_PKG_PRKG1_ST	Q8WZ42	TTN	Q13976	PRKG1	S5686	N5683K	5683	Missense	distal	-3	no	4.272	8.819	EPSD	COSMIC	7.092	Gain
AGC_PKG_PRKG1_ST	Q8WZ42	TTN	Q13976	PRKG1	T5690	G5687R	5687	Missense	distal	-3	no	2.855	7.445	EPSD	COSMIC	7.092	Gain
AGC_PKG_PRKG1_ST	Q8WZ42	TTN	Q13976	PRKG1	S5703	E5699K	5699	Missense	distal	-4	no	7.038	7.698	EPSD	COSMIC	7.092	Gain
AGC_PKG_PRKG1_ST	Q8WZ42	TTN	Q13976	PRKG1	S5795	V5797A	5797	Missense	proximal	2	no	10.523	10.608	EPSD	COSMIC	7.092	Up-regulation
AGC_PKG_PRKG1_ST	Q8WZ42	TTN	Q13976	PRKG1	S5795	P5796L	5796	Missense	proximal	1	no	10.523	10.293	EPSD	COSMIC	7.092	Down-regulation
AGC_PKG_PRKG1_ST	Q8WZ42	TTN	Q13976	PRKG1	S5795	V5799A	5799	Missense	distal	4	no	10.523	10.384	EPSD	COSMIC	7.092	Down-regulation
AGC_PKG_PRKG1_ST	Q8WZ42	TTN	Q13976	PRKG1	S5871	T5869M	5869	Missense	proximal	-2	no	6.975	7.304	EPSD	COSMIC	7.092	Gain
AGC_PKG_PRKG1_ST	Q8WZ42	TTN	Q13976	PRKG1	S6076	T6080P	6080	Missense	distal	4	no	7.774	7.901	EPSD	COSMIC	7.092	Up-regulation
AGC_PKG_PRKG1_ST	Q8WZ42	TTN	Q13976	PRKG1	S6076	T6080N	6080	Missense	distal	4	no	7.774	7.831	EPSD	COSMIC	7.092	Up-regulation
AGC_PKG_PRKG1_ST	Q8WZ42	TTN	Q13976	PRKG1	S6076	A6074D	6074	Missense	proximal	-2	no	7.774	5.326	EPSD	COSMIC	7.092	Loss
AGC_PKG_PRKG1_ST	Q8WZ42	TTN	Q13976	PRKG1	S6076	D6078N	6078	Missense	proximal	2	no	7.774	7.796	EPSD	COSMIC	7.092	Up-regulation
AGC_PKG_PRKG1_ST	Q8WZ42	TTN	Q13976	PRKG1	S6076	T6080M	6080	Missense	distal	4	no	7.774	7.792	EPSD	COSMIC	7.092	Up-regulation
AGC_PKG_PRKG1_ST	Q8WZ42	TTN	Q13976	PRKG1	S6076	S6076L	6076	Missense	central	0	yes	7.774	0.000	EPSD	COSMIC	7.092	Loss
AGC_PKG_PRKG1_ST	Q8WZ42	TTN	Q13976	PRKG1	S6135	D6134N	6134	Missense	proximal	-1	no	7.965	8.042	EPSD	COSMIC	7.092	Up-regulation
AGC_PKG_PRKG1_ST	Q8WZ42	TTN	Q13976	PRKG1	S6135	Q6137H	6137	Missense	proximal	2	no	7.965	7.930	EPSD	COSMIC	7.092	Down-regulation
AGC_PKG_PRKG1_ST	Q8WZ42	TTN	Q13976	PRKG1	S6339	G6336R	6336	Missense	distal	-3	no	4.854	9.444	EPSD	COSMIC	7.092	Gain
AGC_PKG_PRKG1_ST	Q8WZ42	TTN	Q13976	PRKG1	S6920	A6914S	6914	Missense	distal	-6	no	9.306	9.350	EPSD	COSMIC	7.092	Up-regulation
AGC_PKG_PRKG1_ST	Q8WZ42	TTN	Q13976	PRKG1	S6920	D6921N	6921	Missense	proximal	1	no	9.306	9.436	EPSD	COSMIC	7.092	Up-regulation
AGC_PKG_PRKG1_ST	Q8WZ42	TTN	Q13976	PRKG1	S7308	G7306R	7306	Missense	proximal	-2	no	8.075	11.563	EPSD	COSMIC	7.092	Up-regulation
AGC_PKG_PRKG1_ST	Q8WZ42	TTN	Q13976	PRKG1	S7308	I7315V	7315	Missense	distal	7	no	8.075	8.129	EPSD	COSMIC	7.092	Up-regulation
AGC_PKG_PRKG1_ST	Q8WZ42	TTN	Q13976	PRKG1	S7330	D7329H	7329	Missense	proximal	-1	no	9.896	10.011	EPSD	COSMIC	7.092	Up-regulation
AGC_PKG_PRKG1_ST	Q8WZ42	TTN	Q13976	PRKG1	S7330	H7333Y	7333	Missense	distal	3	no	9.896	9.997	EPSD	COSMIC;CCLE	7.092	Up-regulation
AGC_PKG_PRKG1_ST	Q8WZ42	TTN	Q13976	PRKG1	S7485	I7491N	7491	Missense	distal	6	no	7.912	7.723	EPSD	COSMIC	7.092	Down-regulation
AGC_PKG_PRKG1_ST	Q8WZ42	TTN	Q13976	PRKG1	S7485	P7478S	7478	Missense	distal	-7	no	7.912	8.679	EPSD	COSMIC	7.092	Up-regulation
AGC_PKG_PRKG1_ST	Q8WZ42	TTN	Q13976	PRKG1	S7485	D7486H	7486	Missense	proximal	1	no	7.912	8.085	EPSD	COSMIC	7.092	Up-regulation
AGC_PKG_PRKG1_ST	Q8WZ42	TTN	Q13976	PRKG1	S7563	C7562F	7562	Missense	proximal	-1	no	9.410	9.417	EPSD	COSMIC	7.092	Up-regulation
AGC_PKG_PRKG1_ST	Q8WZ42	TTN	Q13976	PRKG1	S7563	C7562W	7562	Missense	proximal	-1	no	9.410	9.355	EPSD	COSMIC	7.092	Down-regulation
AGC_PKG_PRKG1_ST	Q8WZ42	TTN	Q13976	PRKG1	S7613	E7611Q	7611	Missense	proximal	-2	no	8.208	10.243	EPSD	COSMIC	7.092	Up-regulation
AGC_PKG_PRKG1_ST	Q8WZ42	TTN	Q13976	PRKG1	S7613	D7608H	7608	Missense	distal	-5	no	8.208	8.094	EPSD	COSMIC	7.092	Down-regulation
AGC_PKG_PRKG1_ST	Q8WZ42	TTN	Q13976	PRKG1	S7613	K7607R	7607	Missense	distal	-6	no	8.208	8.372	EPSD	COSMIC	7.092	Up-regulation
AGC_PKG_PRKG1_ST	Q8WZ42	TTN	Q13976	PRKG1	S7613	A7614E	7614	Missense	proximal	1	no	8.208	7.960	EPSD	COSMIC	7.092	Down-regulation
AGC_PKG_PRKG1_ST	Q8WZ42	TTN	Q13976	PRKG1	S7628	V7626M	7626	Missense	proximal	-2	no	6.504	7.199	EPSD	COSMIC	7.092	Gain
AGC_PKG_PRKG1_ST	Q8WZ42	TTN	Q13976	PRKG1	S7989	K7982E	7982	Missense	distal	-7	no	7.261	6.260	EPSD	COSMIC	7.092	Loss
AGC_PKG_PRKG1_ST	Q8WZ42	TTN	Q13976	PRKG1	S8426	V8432I	8432	Missense	distal	6	no	7.434	7.537	EPSD	COSMIC	7.092	Up-regulation
AGC_PKG_PRKG1_ST	Q8WZ42	TTN	Q13976	PRKG1	S8426	V8431A	8431	Missense	distal	5	no	7.434	7.484	EPSD	COSMIC	7.092	Up-regulation
AGC_PKG_PRKG1_ST	Q8WZ42	TTN	Q13976	PRKG1	S8426	L8425P	8425	Missense	proximal	-1	no	7.434	7.531	EPSD	COSMIC	7.092	Up-regulation
AGC_PKG_PRKG1_ST	Q8WZ42	TTN	Q13976	PRKG1	S8740	L8742P	8742	Missense	proximal	2	no	7.356	7.401	EPSD	COSMIC	7.092	Up-regulation
AGC_PKG_PRKG1_ST	Q8WZ42	TTN	Q13976	PRKG1	S8740	V8733F	8733	Missense	distal	-7	no	7.356	7.573	EPSD	COSMIC	7.092	Up-regulation
AGC_PKG_PRKG1_ST	Q8WZ42	TTN	Q13976	PRKG1	S9117	S9122I	9122	Missense	distal	5	no	7.162	7.062	EPSD	COSMIC	7.092	Loss
AGC_PKG_PRKG1_ST	Q8WZ42	TTN	Q13976	PRKG1	S9117	S9122R	9122	Missense	distal	5	no	7.162	7.185	EPSD	COSMIC	7.092	Up-regulation
AGC_PKG_PRKG1_ST	Q8WZ42	TTN	Q13976	PRKG1	S9117	A9114D	9114	Missense	distal	-3	no	7.162	3.253	EPSD	COSMIC;CCLE	7.092	Loss
AGC_PKG_PRKG1_ST	Q8WZ42	TTN	Q13976	PRKG1	S9117	R9118I	9118	Missense	proximal	1	no	7.162	6.523	EPSD	COSMIC	7.092	Loss
AGC_PKG_PRKG1_ST	Q8WZ42	TTN	Q13976	PRKG1	S9117	S9117A	9117	Missense	central	0	yes	7.162	0.000	EPSD	COSMIC	7.092	Loss
AGC_PKG_PRKG1_ST	Q8WZ42	TTN	Q13976	PRKG1	S9183	E9190K	9190	Missense	distal	7	no	11.457	11.541	EPSD	COSMIC	7.092	Up-regulation
AGC_PKG_PRKG1_ST	Q8WZ42	TTN	Q13976	PRKG1	S9183	E9187A	9187	Missense	distal	4	no	11.457	11.357	EPSD	COSMIC;CCLE	7.092	Down-regulation
AGC_PKG_PRKG1_ST	Q8WZ42	TTN	Q13976	PRKG1	S9183	E9190D	9190	Missense	distal	7	no	11.457	11.443	EPSD	COSMIC	7.092	Down-regulation
AGC_PKG_PRKG1_ST	Q8WZ42	TTN	Q13976	PRKG1	S9578	T9580I	9580	Missense	proximal	2	no	11.799	11.704	EPSD	COSMIC	7.092	Down-regulation
AGC_PKG_PRKG1_ST	Q8WZ42	TTN	Q13976	PRKG1	S9578	V9583D	9583	Missense	distal	5	no	11.799	11.795	EPSD	COSMIC	7.092	Down-regulation
AGC_PKG_PRKG1_ST	Q8WZ42	TTN	Q13976	PRKG1	S9578	R9576I	9576	Missense	proximal	-2	no	11.799	5.794	EPSD	COSMIC	7.092	Loss
AGC_PKG_PRKG1_ST	Q8WZ42	TTN	Q13976	PRKG1	S9578	L9577Q	9577	Missense	proximal	-1	no	11.799	12.037	EPSD	COSMIC	7.092	Up-regulation
AGC_PKG_PRKG1_ST	Q8WZ42	TTN	Q13976	PRKG1	S10146	E10152D	10152	Missense	distal	6	no	7.825	7.852	EPSD	COSMIC	7.092	Up-regulation
AGC_PKG_PRKG1_ST	Q8WZ42	TTN	Q13976	PRKG1	S10146	E10153K	10153	Missense	distal	7	no	7.825	7.910	EPSD	COSMIC	7.092	Up-regulation
AGC_PKG_PRKG1_ST	Q8WZ42	TTN	Q13976	PRKG1	S10146	V10150I	10150	Missense	distal	4	no	7.825	7.887	EPSD	COSMIC	7.092	Up-regulation
AGC_PKG_PRKG1_ST	Q8WZ42	TTN	Q13976	PRKG1	S10146	S10146F	10146	Missense	central	0	yes	7.825	0.000	EPSD	COSMIC	7.092	Loss
AGC_PKG_PRKG1_ST	Q8WZ42	TTN	Q13976	PRKG1	S10146	I10140V	10140	Missense	distal	-6	no	7.825	8.081	EPSD	COSMIC	7.092	Up-regulation
AGC_PKG_PRKG1_ST	Q8WZ42	TTN	Q13976	PRKG1	S10146	P10149A	10149	Missense	distal	3	no	7.825	7.600	EPSD	COSMIC	7.092	Down-regulation
AGC_PKG_PRKG1_ST	Q8WZ42	TTN	Q13976	PRKG1	S10146	P10142S	10142	Missense	distal	-4	no	7.825	8.248	EPSD	COSMIC	7.092	Up-regulation
AGC_PKG_PRKG1_ST	Q8WZ42	TTN	Q13976	PRKG1	S10321	E10320K	10320	Missense	proximal	-1	no	8.406	8.568	EPSD	COSMIC	7.092	Up-regulation
AGC_PKG_PRKG1_ST	Q8WZ42	TTN	Q13976	PRKG1	S10321	Q10317R	10317	Missense	distal	-4	no	8.406	8.802	EPSD	COSMIC	7.092	Up-regulation
AGC_PKG_PRKG1_ST	Q8WZ42	TTN	Q13976	PRKG1	S10321	P10324A	10324	Missense	distal	3	no	8.406	8.181	EPSD	COSMIC	7.092	Down-regulation
AGC_PKG_PRKG1_ST	Q8WZ42	TTN	Q13976	PRKG1	S10321	R10318T	10318	Missense	distal	-3	no	8.406	3.241	EPSD	COSMIC;CCLE	7.092	Loss
AGC_PKG_PRKG1_ST	Q8WZ42	TTN	Q13976	PRKG1	S10321	P10322Q	10322	Missense	proximal	1	no	8.406	8.679	EPSD	COSMIC	7.092	Up-regulation
AGC_PKG_PRKG1_ST	Q8WZ42	TTN	Q13976	PRKG1	S10402	E10399K	10399	Missense	distal	-3	no	4.448	9.031	EPSD	COSMIC	7.092	Gain
AGC_PKG_PRKG1_ST	Q8WZ42	TTN	Q13976	PRKG1	T10658	A10656V	10656	Missense	proximal	-2	no	8.296	7.793	EPSD	COSMIC	7.092	Down-regulation
AGC_PKG_PRKG1_ST	Q8WZ42	TTN	Q13976	PRKG1	T10658	E10662K	10662	Missense	distal	4	no	8.296	8.180	EPSD	COSMIC	7.092	Down-regulation
AGC_PKG_PRKG1_ST	Q8WZ42	TTN	Q13976	PRKG1	T10658	T10658I	10658	Missense	central	0	yes	8.296	0.000	EPSD	COSMIC	7.092	Loss
AGC_PKG_PRKG1_ST	Q8WZ42	TTN	Q13976	PRKG1	S11223	E11216K	11216	Missense	distal	-7	no	7.439	8.440	EPSD	COSMIC	7.092	Up-regulation
AGC_PKG_PRKG1_ST	Q8WZ42	TTN	Q13976	PRKG1	S11223	P11219Q	11219	Missense	distal	-4	no	7.439	7.937	EPSD	COSMIC	7.092	Up-regulation
AGC_PKG_PRKG1_ST	Q8WZ42	TTN	Q13976	PRKG1	S11223	P11227S	11227	Missense	distal	4	no	7.439	7.288	EPSD	COSMIC	7.092	Down-regulation
AGC_PKG_PRKG1_ST	Q8WZ42	TTN	Q13976	PRKG1	S11503	E11502K	11502	Missense	proximal	-1	no	8.100	8.261	EPSD	COSMIC	7.092	Up-regulation
AGC_PKG_PRKG1_ST	Q8WZ42	TTN	Q13976	PRKG1	S11503	P11505L	11505	Missense	proximal	2	no	8.100	8.055	EPSD	COSMIC	7.092	Down-regulation
AGC_PKG_PRKG1_ST	Q8WZ42	TTN	Q13976	PRKG1	S11503	P11505T	11505	Missense	proximal	2	no	8.100	8.166	EPSD	COSMIC	7.092	Up-regulation
AGC_PKG_PRKG1_ST	Q8WZ42	TTN	Q13976	PRKG1	S11503	P11501S	11501	Missense	proximal	-2	no	8.100	8.451	EPSD	COSMIC	7.092	Up-regulation
AGC_PKG_PRKG1_ST	Q8WZ42	TTN	Q13976	PRKG1	S12009	P12008T	12008	Missense	proximal	-1	no	7.621	7.722	EPSD	COSMIC	7.092	Up-regulation
AGC_PKG_PRKG1_ST	Q8WZ42	TTN	Q13976	PRKG1	S12009	R12015K	12015	Missense	distal	6	no	7.621	7.682	EPSD	COSMIC	7.092	Up-regulation
AGC_PKG_PRKG1_ST	Q8WZ42	TTN	Q13976	PRKG1	S12022	P12027S	12027	Missense	distal	5	no	10.899	10.971	EPSD	COSMIC	7.092	Up-regulation
AGC_PKG_PRKG1_ST	Q8WZ42	TTN	Q13976	PRKG1	S12022	P12020S	12020	Missense	proximal	-2	no	10.899	11.250	EPSD	COSMIC	7.092	Up-regulation
AGC_PKG_PRKG1_ST	Q8WZ42	TTN	Q13976	PRKG1	S12022	P12028S	12028	Missense	distal	6	no	10.899	10.663	EPSD	COSMIC	7.092	Down-regulation
AGC_PKG_PRKG1_ST	Q8WZ42	TTN	Q13976	PRKG1	S12022	R12015K	12015	Missense	distal	-7	no	10.899	10.433	EPSD	COSMIC	7.092	Down-regulation
AGC_PKG_PRKG1_ST	Q8WZ42	TTN	Q13976	PRKG1	S12022	K12017N	12017	Missense	distal	-5	no	10.899	11.039	EPSD	COSMIC	7.092	Up-regulation
AGC_PKG_PRKG1_ST	Q8WZ42	TTN	Q13976	PRKG1	S12022	G12021A	12021	Missense	proximal	-1	no	10.899	10.956	EPSD	COSMIC	7.092	Up-regulation
AGC_PKG_PRKG1_ST	Q8WZ42	TTN	Q13976	PRKG1	S12340	E12337G	12337	Missense	distal	-3	no	5.040	7.390	EPSD	COSMIC	7.092	Gain
AGC_PKG_PRKG1_ST	Q8WZ42	TTN	Q13976	PRKG1	S12491	K12488R	12488	Missense	distal	-3	no	9.038	11.396	EPSD	COSMIC	7.092	Up-regulation
AGC_PKG_PRKG1_ST	Q8WZ42	TTN	Q13976	PRKG1	S12491	G12487V	12487	Missense	distal	-4	no	9.038	8.721	EPSD	COSMIC	7.092	Down-regulation
AGC_PKG_PRKG1_ST	Q8WZ42	TTN	Q13976	PRKG1	T12718	P12716R	12716	Missense	proximal	-2	no	4.058	7.817	EPSD	COSMIC	7.092	Gain
AGC_PKG_PRKG1_ST	Q8WZ42	TTN	Q13976	PRKG1	S12900	M12903V	12903	Missense	distal	3	no	7.652	7.842	EPSD	COSMIC	7.092	Up-regulation
AGC_PKG_PRKG1_ST	Q8WZ42	TTN	Q13976	PRKG1	S12900	R12899G	12899	Missense	proximal	-1	no	7.652	7.488	EPSD	COSMIC	7.092	Down-regulation
AGC_PKG_PRKG1_ST	Q8WZ42	TTN	Q13976	PRKG1	S12902	T12909N	12909	Missense	distal	7	no	8.760	8.713	EPSD	COSMIC	7.092	Down-regulation
AGC_PKG_PRKG1_ST	Q8WZ42	TTN	Q13976	PRKG1	S12902	M12903V	12903	Missense	proximal	1	no	8.760	8.531	EPSD	COSMIC	7.092	Down-regulation
AGC_PKG_PRKG1_ST	Q8WZ42	TTN	Q13976	PRKG1	S12902	R12899G	12899	Missense	distal	-3	no	8.760	4.170	EPSD	COSMIC	7.092	Loss
AGC_PKG_PRKG1_ST	Q8WZ42	TTN	Q13976	PRKG1	S12911	S12918F	12918	Missense	distal	7	no	7.122	7.047	EPSD	COSMIC	7.092	Loss
AGC_PKG_PRKG1_ST	Q8WZ42	TTN	Q13976	PRKG1	S12911	T12909N	12909	Missense	proximal	-2	no	7.122	6.294	EPSD	COSMIC	7.092	Loss
AGC_PKG_PRKG1_ST	Q8WZ42	TTN	Q13976	PRKG1	S12911	S12911W	12911	Missense	central	0	yes	7.122	0.000	EPSD	COSMIC	7.092	Loss
AGC_PKG_PRKG1_ST	Q8WZ42	TTN	Q13976	PRKG1	S13113	A13107V	13107	Missense	distal	-6	no	7.486	7.150	EPSD	COSMIC	7.092	Down-regulation
AGC_PKG_PRKG1_ST	Q8WZ42	TTN	Q13976	PRKG1	S13113	N13109I	13109	Missense	distal	-4	no	7.486	7.019	EPSD	COSMIC	7.092	Loss
AGC_PKG_PRKG1_ST	Q8WZ42	TTN	Q13976	PRKG1	S13113	K13111I	13111	Missense	proximal	-2	no	7.486	2.958	EPSD	COSMIC	7.092	Loss
AGC_PKG_PRKG1_ST	Q8WZ42	TTN	Q13976	PRKG1	T13178	H13177R	13177	Missense	proximal	-1	no	7.324	7.472	EPSD	COSMIC	7.092	Up-regulation
AGC_PKG_PRKG1_ST	Q8WZ42	TTN	Q13976	PRKG1	T13178	H13177N	13177	Missense	proximal	-1	no	7.324	7.286	EPSD	COSMIC	7.092	Down-regulation
AGC_PKG_PRKG1_ST	Q8WZ42	TTN	Q13976	PRKG1	T13178	R13171C	13171	Missense	distal	-7	no	7.324	5.896	EPSD	COSMIC	7.092	Loss
AGC_PKG_PRKG1_ST	Q8WZ42	TTN	Q13976	PRKG1	T13180	H13177R	13177	Missense	distal	-3	no	1.568	7.636	EPSD	COSMIC	7.092	Gain
AGC_PKG_PRKG1_ST	Q8WZ42	TTN	Q13976	PRKG1	S13380	E13387K	13387	Missense	distal	7	no	8.750	8.835	EPSD	COSMIC	7.092	Up-regulation
AGC_PKG_PRKG1_ST	Q8WZ42	TTN	Q13976	PRKG1	S13380	T13379P	13379	Missense	proximal	-1	no	8.750	8.649	EPSD	COSMIC	7.092	Down-regulation
AGC_PKG_PRKG1_ST	Q8WZ42	TTN	Q13976	PRKG1	S13380	M13382I	13382	Missense	proximal	2	no	8.750	8.664	EPSD	COSMIC	7.092	Down-regulation
AGC_PKG_PRKG1_ST	Q8WZ42	TTN	Q13976	PRKG1	S13380	R13378P	13378	Missense	proximal	-2	no	8.750	4.991	EPSD	COSMIC	7.092	Loss
AGC_PKG_PRKG1_ST	Q8WZ42	TTN	Q13976	PRKG1	S13380	R13378C	13378	Missense	proximal	-2	no	8.750	4.022	EPSD	COSMIC	7.092	Loss
AGC_PKG_PRKG1_ST	Q8WZ42	TTN	Q13976	PRKG1	S13380	T13376I	13376	Missense	distal	-4	no	8.750	8.030	EPSD	COSMIC	7.092	Down-regulation
AGC_PKG_PRKG1_ST	Q8WZ42	TTN	Q13976	PRKG1	S14233	Q14236L	14236	Missense	distal	3	no	6.872	7.235	EPSD	COSMIC	7.092	Gain
AGC_PKG_PRKG1_ST	Q8WZ42	TTN	Q13976	PRKG1	T14402	R14399C	14399	Missense	distal	-3	no	7.281	0.259	EPSD	COSMIC	7.092	Loss
AGC_PKG_PRKG1_ST	Q8WZ42	TTN	Q13976	PRKG1	T14402	R14399H	14399	Missense	distal	-3	no	7.281	1.214	EPSD	COSMIC	7.092	Loss
AGC_PKG_PRKG1_ST	Q8WZ42	TTN	Q13976	PRKG1	T14402	D14408N	14408	Missense	distal	6	no	7.281	7.191	EPSD	COSMIC	7.092	Down-regulation
AGC_PKG_PRKG1_ST	Q8WZ42	TTN	Q13976	PRKG1	T14402	I14403M	14403	Missense	proximal	1	no	7.281	7.639	EPSD	COSMIC	7.092	Up-regulation
AGC_PKG_PRKG1_ST	Q8WZ42	TTN	Q13976	PRKG1	T14402	R14399S	14399	Missense	distal	-3	no	7.281	1.793	EPSD	COSMIC	7.092	Loss
AGC_PKG_PRKG1_ST	Q8WZ42	TTN	Q13976	PRKG1	S14457	E14455K	14455	Missense	proximal	-2	no	7.907	11.430	EPSD	COSMIC	7.092	Up-regulation
AGC_PKG_PRKG1_ST	Q8WZ42	TTN	Q13976	PRKG1	S14457	R14458W	14458	Missense	proximal	1	no	7.907	7.337	EPSD	COSMIC	7.092	Down-regulation
AGC_PKG_PRKG1_ST	Q8WZ42	TTN	Q13976	PRKG1	S14457	S14457I	14457	Missense	central	0	yes	7.907	0.000	EPSD	COSMIC	7.092	Loss
AGC_PKG_PRKG1_ST	Q8WZ42	TTN	Q13976	PRKG1	S14558	C14564S	14564	Missense	distal	6	no	8.757	8.578	EPSD	COSMIC	7.092	Down-regulation
AGC_PKG_PRKG1_ST	Q8WZ42	TTN	Q13976	PRKG1	S14558	A14563V	14563	Missense	distal	5	no	8.757	8.707	EPSD	COSMIC	7.092	Down-regulation
AGC_PKG_PRKG1_ST	Q8WZ42	TTN	Q13976	PRKG1	S14558	S14558P	14558	Missense	central	0	yes	8.757	0.000	EPSD	COSMIC	7.092	Loss
AGC_PKG_PRKG1_ST	Q8WZ42	TTN	Q13976	PRKG1	T14752	R14750Q	14750	Missense	proximal	-2	no	10.107	7.142	EPSD	COSMIC	7.092	Down-regulation
AGC_PKG_PRKG1_ST	Q8WZ42	TTN	Q13976	PRKG1	T14752	H14758Y	14758	Missense	distal	6	no	10.107	10.192	EPSD	COSMIC	7.092	Up-regulation
AGC_PKG_PRKG1_ST	Q8WZ42	TTN	Q13976	PRKG1	T14752	A14751E	14751	Missense	proximal	-1	no	10.107	9.994	EPSD	COSMIC	7.092	Down-regulation
AGC_PKG_PRKG1_ST	Q8WZ42	TTN	Q13976	PRKG1	S14926	G14923R	14923	Missense	distal	-3	no	6.949	11.539	EPSD	COSMIC	7.092	Gain
AGC_PKG_PRKG1_ST	Q8WZ42	TTN	Q13976	PRKG1	S15263	N15262D	15262	Missense	proximal	-1	no	9.330	9.253	EPSD	COSMIC	7.092	Down-regulation
AGC_PKG_PRKG1_ST	Q8WZ42	TTN	Q13976	PRKG1	S15263	P15265T	15265	Missense	proximal	2	no	9.330	9.397	EPSD	COSMIC	7.092	Up-regulation
AGC_PKG_PRKG1_ST	Q8WZ42	TTN	Q13976	PRKG1	S15263	R15264H	15264	Missense	proximal	1	no	9.330	8.994	EPSD	COSMIC	7.092	Down-regulation
AGC_PKG_PRKG1_ST	Q8WZ42	TTN	Q13976	PRKG1	T15452	R15446K	15446	Missense	distal	-6	no	8.948	8.784	EPSD	COSMIC	7.092	Down-regulation
AGC_PKG_PRKG1_ST	Q8WZ42	TTN	Q13976	PRKG1	T15452	E15447Q	15447	Missense	distal	-5	no	8.948	8.795	EPSD	COSMIC	7.092	Down-regulation
AGC_PKG_PRKG1_ST	Q8WZ42	TTN	Q13976	PRKG1	T15452	G15459D	15459	Missense	distal	7	no	8.948	8.920	EPSD	COSMIC	7.092	Down-regulation
AGC_PKG_PRKG1_ST	Q8WZ42	TTN	Q13976	PRKG1	T15452	R15450T	15450	Missense	proximal	-2	no	8.948	5.356	EPSD	COSMIC	7.092	Loss
AGC_PKG_PRKG1_ST	Q8WZ42	TTN	Q13976	PRKG1	S15615	L15612M	15612	Missense	distal	-3	no	6.602	8.443	EPSD	COSMIC	7.092	Gain
AGC_PKG_PRKG1_ST	Q8WZ42	TTN	Q13976	PRKG1	S15682	D15684G	15684	Missense	proximal	2	no	8.818	8.834	EPSD	COSMIC	7.092	Up-regulation
AGC_PKG_PRKG1_ST	Q8WZ42	TTN	Q13976	PRKG1	S15682	R15680C	15680	Missense	proximal	-2	no	8.818	4.089	EPSD	COSMIC;CCLE	7.092	Loss
AGC_PKG_PRKG1_ST	Q8WZ42	TTN	Q13976	PRKG1	S15682	K15687T	15687	Missense	distal	5	no	8.818	8.809	EPSD	COSMIC	7.092	Down-regulation
AGC_PKG_PRKG1_ST	Q8WZ42	TTN	Q13976	PRKG1	S15682	G15689A	15689	Missense	distal	7	no	8.818	8.870	EPSD	COSMIC	7.092	Up-regulation
AGC_PKG_PRKG1_ST	Q8WZ42	TTN	Q13976	PRKG1	S15691	D15684G	15684	Missense	distal	-7	no	6.549	7.095	EPSD	COSMIC	7.092	Gain
AGC_PKG_PRKG1_ST	Q8WZ42	TTN	Q13976	PRKG1	S15744	P15751S	15751	Missense	distal	7	no	10.204	10.306	EPSD	COSMIC	7.092	Up-regulation
AGC_PKG_PRKG1_ST	Q8WZ42	TTN	Q13976	PRKG1	S15744	F15737I	15737	Missense	distal	-7	no	10.204	9.470	EPSD	COSMIC	7.092	Down-regulation
AGC_PKG_PRKG1_ST	Q8WZ42	TTN	Q13976	PRKG1	S15744	E15750K	15750	Missense	distal	6	no	10.204	9.986	EPSD	COSMIC	7.092	Down-regulation
AGC_PKG_PRKG1_ST	Q8WZ42	TTN	Q13976	PRKG1	T15989	E15995D	15995	Missense	distal	6	no	7.699	7.725	EPSD	COSMIC	7.092	Up-regulation
AGC_PKG_PRKG1_ST	Q8WZ42	TTN	Q13976	PRKG1	T15989	E15992K	15992	Missense	distal	3	no	7.699	7.525	EPSD	COSMIC	7.092	Down-regulation
AGC_PKG_PRKG1_ST	Q8WZ42	TTN	Q13976	PRKG1	T15989	T15989N	15989	Missense	central	0	yes	7.699	0.000	EPSD	COSMIC	7.092	Loss
AGC_PKG_PRKG1_ST	Q8WZ42	TTN	Q13976	PRKG1	T15989	R15986Q	15986	Missense	distal	-3	no	7.699	3.864	EPSD	COSMIC	7.092	Loss
AGC_PKG_PRKG1_ST	Q8WZ42	TTN	Q13976	PRKG1	S16086	G16083R	16083	Missense	distal	-3	no	4.605	9.195	EPSD	COSMIC	7.092	Gain
AGC_PKG_PRKG1_ST	Q8WZ42	TTN	Q13976	PRKG1	S16236	D16241H	16241	Missense	distal	5	no	10.991	11.032	EPSD	COSMIC	7.092	Up-regulation
AGC_PKG_PRKG1_ST	Q8WZ42	TTN	Q13976	PRKG1	S16236	L16240P	16240	Missense	distal	4	no	10.991	10.891	EPSD	COSMIC	7.092	Down-regulation
AGC_PKG_PRKG1_ST	Q8WZ42	TTN	Q13976	PRKG1	S16236	D16241Y	16241	Missense	distal	5	no	10.991	11.001	EPSD	COSMIC	7.092	Up-regulation
AGC_PKG_PRKG1_ST	Q8WZ42	TTN	Q13976	PRKG1	S16329	I16335V	16335	Missense	distal	6	no	7.660	7.556	EPSD	COSMIC;CCLE	7.092	Down-regulation
AGC_PKG_PRKG1_ST	Q8WZ42	TTN	Q13976	PRKG1	S16329	T16323A	16323	Missense	distal	-6	no	7.660	7.699	EPSD	COSMIC	7.092	Up-regulation
AGC_PKG_PRKG1_ST	Q8WZ42	TTN	Q13976	PRKG1	S16329	K16325M	16325	Missense	distal	-4	no	7.660	7.361	EPSD	COSMIC	7.092	Down-regulation
AGC_PKG_PRKG1_ST	Q8WZ42	TTN	Q13976	PRKG1	S16329	D16333Y	16333	Missense	distal	4	no	7.660	7.675	EPSD	COSMIC	7.092	Up-regulation
AGC_PKG_PRKG1_ST	Q8WZ42	TTN	Q13976	PRKG1	S16329	R16331I	16331	Missense	proximal	2	no	7.660	7.544	EPSD	COSMIC	7.092	Down-regulation
AGC_PKG_PRKG1_ST	Q8WZ42	TTN	Q13976	PRKG1	S16329	T16334I	16334	Missense	distal	5	no	7.660	7.564	EPSD	COSMIC	7.092	Down-regulation
AGC_PKG_PRKG1_ST	Q8WZ42	TTN	Q13976	PRKG1	T16334	V16337G	16337	Missense	distal	3	no	7.497	7.433	EPSD	COSMIC	7.092	Down-regulation
AGC_PKG_PRKG1_ST	Q8WZ42	TTN	Q13976	PRKG1	T16334	I16335V	16335	Missense	proximal	1	no	7.497	7.626	EPSD	COSMIC;CCLE	7.092	Up-regulation
AGC_PKG_PRKG1_ST	Q8WZ42	TTN	Q13976	PRKG1	T16334	D16333Y	16333	Missense	proximal	-1	no	7.497	7.567	EPSD	COSMIC	7.092	Up-regulation
AGC_PKG_PRKG1_ST	Q8WZ42	TTN	Q13976	PRKG1	T16334	R16331I	16331	Missense	distal	-3	no	7.497	-1.010	EPSD	COSMIC	7.092	Loss
AGC_PKG_PRKG1_ST	Q8WZ42	TTN	Q13976	PRKG1	T16334	T16334I	16334	Missense	central	0	yes	7.497	0.000	EPSD	COSMIC	7.092	Loss
AGC_PKG_PRKG1_ST	Q8WZ42	TTN	Q13976	PRKG1	S16646	V16640G	16640	Missense	distal	-6	no	7.331	7.493	EPSD	COSMIC	7.092	Up-regulation
AGC_PKG_PRKG1_ST	Q8WZ42	TTN	Q13976	PRKG1	S16646	D16642H	16642	Missense	distal	-4	no	7.331	7.685	EPSD	COSMIC	7.092	Up-regulation
AGC_PKG_PRKG1_ST	Q8WZ42	TTN	Q13976	PRKG1	S16647	V16640G	16640	Missense	distal	-7	no	7.339	7.683	EPSD	COSMIC	7.092	Up-regulation
AGC_PKG_PRKG1_ST	Q8WZ42	TTN	Q13976	PRKG1	S16647	D16642H	16642	Missense	distal	-5	no	7.339	7.226	EPSD	COSMIC	7.092	Down-regulation
AGC_PKG_PRKG1_ST	Q8WZ42	TTN	Q13976	PRKG1	S16817	S16817R	16817	Missense	central	0	yes	9.144	0.000	EPSD	COSMIC	7.092	Loss
AGC_PKG_PRKG1_ST	Q8WZ42	TTN	Q13976	PRKG1	S16817	T16819M	16819	Missense	proximal	2	no	9.144	9.135	EPSD	COSMIC	7.092	Down-regulation
AGC_PKG_PRKG1_ST	Q8WZ42	TTN	Q13976	PRKG1	S16817	T16819P	16819	Missense	proximal	2	no	9.144	9.077	EPSD	COSMIC	7.092	Down-regulation
AGC_PKG_PRKG1_ST	Q8WZ42	TTN	Q13976	PRKG1	S16854	S16854P	16854	Missense	central	0	yes	8.172	0.000	EPSD	COSMIC	7.092	Loss
AGC_PKG_PRKG1_ST	Q8WZ42	TTN	Q13976	PRKG1	S16854	L16857F	16857	Missense	distal	3	no	8.172	7.986	EPSD	COSMIC	7.092	Down-regulation
AGC_PKG_PRKG1_ST	Q8WZ42	TTN	Q13976	PRKG1	S16854	G16853D	16853	Missense	proximal	-1	no	8.172	8.073	EPSD	COSMIC	7.092	Down-regulation
AGC_PKG_PRKG1_ST	Q8WZ42	TTN	Q13976	PRKG1	S16854	C16855F	16855	Missense	proximal	1	no	8.172	8.207	EPSD	COSMIC;CCLE	7.092	Up-regulation
AGC_PKG_PRKG1_ST	Q8WZ42	TTN	Q13976	PRKG1	S16854	K16860N	16860	Missense	distal	6	no	8.172	8.326	EPSD	COSMIC	7.092	Up-regulation
AGC_PKG_PRKG1_ST	Q8WZ42	TTN	Q13976	PRKG1	T16931	V16924M	16924	Missense	distal	-7	no	7.054	7.659	EPSD	COSMIC	7.092	Gain
AGC_PKG_PRKG1_ST	Q8WZ42	TTN	Q13976	PRKG1	S17116	I17110T	17110	Missense	distal	-6	no	6.813	7.365	EPSD	COSMIC	7.092	Gain
AGC_PKG_PRKG1_ST	Q8WZ42	TTN	Q13976	PRKG1	T17118	G17119C	17119	Missense	proximal	1	no	8.734	8.650	EPSD	COSMIC	7.092	Down-regulation
AGC_PKG_PRKG1_ST	Q8WZ42	TTN	Q13976	PRKG1	T17118	T17124A	17124	Missense	distal	6	no	8.734	8.726	EPSD	COSMIC	7.092	Down-regulation
AGC_PKG_PRKG1_ST	Q8WZ42	TTN	Q13976	PRKG1	S17133	G17130R	17130	Missense	distal	-3	no	5.522	10.113	EPSD	COSMIC	7.092	Gain
AGC_PKG_PRKG1_ST	Q8WZ42	TTN	Q13976	PRKG1	S17195	H17193R	17193	Missense	proximal	-2	no	4.215	8.472	EPSD	COSMIC	7.092	Gain
AGC_PKG_PRKG1_ST	Q8WZ42	TTN	Q13976	PRKG1	S17196	H17193R	17193	Missense	distal	-3	no	3.911	9.978	EPSD	COSMIC	7.092	Gain
AGC_PKG_PRKG1_ST	Q8WZ42	TTN	Q13976	PRKG1	S17448	R17445K	17445	Missense	distal	-3	no	7.953	5.595	EPSD	COSMIC	7.092	Loss
AGC_PKG_PRKG1_ST	Q8WZ42	TTN	Q13976	PRKG1	S17521	K17525N	17525	Missense	distal	4	no	7.145	7.221	EPSD	COSMIC	7.092	Up-regulation
AGC_PKG_PRKG1_ST	Q8WZ42	TTN	Q13976	PRKG1	T17591	W17590R	17590	Missense	proximal	-1	no	8.843	9.100	EPSD	COSMIC	7.092	Up-regulation
AGC_PKG_PRKG1_ST	Q8WZ42	TTN	Q13976	PRKG1	T17591	E17584K	17584	Missense	distal	-7	no	8.843	9.845	EPSD	COSMIC	7.092	Up-regulation
AGC_PKG_PRKG1_ST	Q8WZ42	TTN	Q13976	PRKG1	S17770	K17772Q	17772	Missense	proximal	2	no	9.348	9.356	EPSD	COSMIC	7.092	Up-regulation
AGC_PKG_PRKG1_ST	Q8WZ42	TTN	Q13976	PRKG1	S17770	R17768H	17768	Missense	proximal	-2	no	9.348	5.091	EPSD	COSMIC	7.092	Loss
AGC_PKG_PRKG1_ST	Q8WZ42	TTN	Q13976	PRKG1	S17778	K17772Q	17772	Missense	distal	-6	no	7.633	7.501	EPSD	COSMIC	7.092	Down-regulation
AGC_PKG_PRKG1_ST	Q8WZ42	TTN	Q13976	PRKG1	T17979	E17978G	17978	Missense	proximal	-1	no	7.685	7.740	EPSD	COSMIC	7.092	Up-regulation
AGC_PKG_PRKG1_ST	Q8WZ42	TTN	Q13976	PRKG1	T17979	S17981C	17981	Missense	proximal	2	no	7.685	7.605	EPSD	COSMIC	7.092	Down-regulation
AGC_PKG_PRKG1_ST	Q8WZ42	TTN	Q13976	PRKG1	T17979	E17978K	17978	Missense	proximal	-1	no	7.685	7.846	EPSD	COSMIC	7.092	Up-regulation
AGC_PKG_PRKG1_ST	Q8WZ42	TTN	Q13976	PRKG1	T17979	S17981T	17981	Missense	proximal	2	no	7.685	7.653	EPSD	COSMIC	7.092	Down-regulation
AGC_PKG_PRKG1_ST	Q8WZ42	TTN	Q13976	PRKG1	T17979	R17983Q	17983	Missense	distal	4	no	7.685	7.745	EPSD	COSMIC	7.092	Up-regulation
AGC_PKG_PRKG1_ST	Q8WZ42	TTN	Q13976	PRKG1	T17979	S17981Y	17981	Missense	proximal	2	no	7.685	7.593	EPSD	COSMIC	7.092	Down-regulation
AGC_PKG_PRKG1_ST	Q8WZ42	TTN	Q13976	PRKG1	T17988	D17990N	17990	Missense	proximal	2	no	7.822	7.845	EPSD	COSMIC	7.092	Up-regulation
AGC_PKG_PRKG1_ST	Q8WZ42	TTN	Q13976	PRKG1	T17988	P17991T	17991	Missense	distal	3	no	7.822	7.564	EPSD	COSMIC	7.092	Down-regulation
AGC_PKG_PRKG1_ST	Q8WZ42	TTN	Q13976	PRKG1	T17988	S17981C	17981	Missense	distal	-7	no	7.822	7.026	EPSD	COSMIC	7.092	Loss
AGC_PKG_PRKG1_ST	Q8WZ42	TTN	Q13976	PRKG1	T17988	S17981T	17981	Missense	distal	-7	no	7.822	7.608	EPSD	COSMIC	7.092	Down-regulation
AGC_PKG_PRKG1_ST	Q8WZ42	TTN	Q13976	PRKG1	T17988	R17983Q	17983	Missense	distal	-5	no	7.822	7.943	EPSD	COSMIC	7.092	Up-regulation
AGC_PKG_PRKG1_ST	Q8WZ42	TTN	Q13976	PRKG1	T17988	S17981Y	17981	Missense	distal	-7	no	7.822	7.032	EPSD	COSMIC	7.092	Loss
AGC_PKG_PRKG1_ST	Q8WZ42	TTN	Q13976	PRKG1	S18166	R18164T	18164	Missense	proximal	-2	no	8.502	4.909	EPSD	COSMIC	7.092	Loss
AGC_PKG_PRKG1_ST	Q8WZ42	TTN	Q13976	PRKG1	S18166	R18164K	18164	Missense	proximal	-2	no	8.502	7.024	EPSD	COSMIC	7.092	Loss
AGC_PKG_PRKG1_ST	Q8WZ42	TTN	Q13976	PRKG1	T18505	R18503H	18503	Missense	proximal	-2	no	10.443	6.186	EPSD	COSMIC	7.092	Loss
AGC_PKG_PRKG1_ST	Q8WZ42	TTN	Q13976	PRKG1	T18505	C18500R	18500	Missense	distal	-5	no	10.443	10.187	EPSD	COSMIC	7.092	Down-regulation
AGC_PKG_PRKG1_ST	Q8WZ42	TTN	Q13976	PRKG1	T18577	T18577N	18577	Missense	central	0	yes	10.483	0.000	EPSD	COSMIC	7.092	Loss
AGC_PKG_PRKG1_ST	Q8WZ42	TTN	Q13976	PRKG1	T18577	R18574T	18574	Missense	distal	-3	no	10.483	5.318	EPSD	COSMIC	7.092	Loss
AGC_PKG_PRKG1_ST	Q8WZ42	TTN	Q13976	PRKG1	T18577	T18573A	18573	Missense	distal	-4	no	10.483	10.597	EPSD	COSMIC	7.092	Up-regulation
AGC_PKG_PRKG1_ST	Q8WZ42	TTN	Q13976	PRKG1	T18577	Q18571K	18571	Missense	distal	-6	no	10.483	10.615	EPSD	COSMIC	7.092	Up-regulation
AGC_PKG_PRKG1_ST	Q8WZ42	TTN	Q13976	PRKG1	T18577	G18584D	18584	Missense	distal	7	no	10.483	10.455	EPSD	COSMIC	7.092	Down-regulation
AGC_PKG_PRKG1_ST	Q8WZ42	TTN	Q13976	PRKG1	S18976	K18969N	18969	Missense	distal	-7	no	7.647	6.872	EPSD	COSMIC	7.092	Loss
AGC_PKG_PRKG1_ST	Q8WZ42	TTN	Q13976	PRKG1	S18976	N18971S	18971	Missense	distal	-5	no	7.647	7.554	EPSD	COSMIC	7.092	Down-regulation
AGC_PKG_PRKG1_ST	Q8WZ42	TTN	Q13976	PRKG1	S18976	I18977V	18977	Missense	proximal	1	no	7.647	7.776	EPSD	COSMIC	7.092	Up-regulation
AGC_PKG_PRKG1_ST	Q8WZ42	TTN	Q13976	PRKG1	S18976	Q18972K	18972	Missense	distal	-4	no	7.647	7.737	EPSD	COSMIC	7.092	Up-regulation
AGC_PKG_PRKG1_ST	Q8WZ42	TTN	Q13976	PRKG1	T19042	K19039R	19039	Missense	distal	-3	no	4.954	7.312	EPSD	COSMIC	7.092	Gain
AGC_PKG_PRKG1_ST	Q8WZ42	TTN	Q13976	PRKG1	S19189	A19193D	19193	Missense	distal	4	no	8.058	8.172	EPSD	COSMIC	7.092	Up-regulation
AGC_PKG_PRKG1_ST	Q8WZ42	TTN	Q13976	PRKG1	S19189	T19191I	19191	Missense	proximal	2	no	8.058	7.963	EPSD	COSMIC	7.092	Down-regulation
AGC_PKG_PRKG1_ST	Q8WZ42	TTN	Q13976	PRKG1	S19189	A19183V	19183	Missense	distal	-6	no	8.058	7.722	EPSD	COSMIC	7.092	Down-regulation
AGC_PKG_PRKG1_ST	Q8WZ42	TTN	Q13976	PRKG1	S19189	R19182S	19182	Missense	distal	-7	no	8.058	7.426	EPSD	COSMIC	7.092	Down-regulation
AGC_PKG_PRKG1_ST	Q8WZ42	TTN	Q13976	PRKG1	S19189	R19182K	19182	Missense	distal	-7	no	8.058	7.592	EPSD	COSMIC	7.092	Down-regulation
AGC_PKG_PRKG1_ST	Q8WZ42	TTN	Q13976	PRKG1	S19189	K19187T	19187	Missense	proximal	-2	no	8.058	5.943	EPSD	COSMIC	7.092	Loss
AGC_PKG_PRKG1_ST	Q8WZ42	TTN	Q13976	PRKG1	S19604	V19608L	19608	Missense	distal	4	no	8.903	8.995	EPSD	COSMIC	7.092	Up-regulation
AGC_PKG_PRKG1_ST	Q8WZ42	TTN	Q13976	PRKG1	S19604	P19610Q	19610	Missense	distal	6	no	8.903	8.666	EPSD	COSMIC	7.092	Down-regulation
AGC_PKG_PRKG1_ST	Q8WZ42	TTN	Q13976	PRKG1	S19604	P19610L	19610	Missense	distal	6	no	8.903	9.032	EPSD	COSMIC	7.092	Up-regulation
AGC_PKG_PRKG1_ST	Q8WZ42	TTN	Q13976	PRKG1	S19604	A19611E	19611	Missense	distal	7	no	8.903	8.837	EPSD	COSMIC	7.092	Down-regulation
AGC_PKG_PRKG1_ST	Q8WZ42	TTN	Q13976	PRKG1	S19604	S19604Y	19604	Missense	central	0	yes	8.903	0.000	EPSD	COSMIC	7.092	Loss
AGC_PKG_PRKG1_ST	Q8WZ42	TTN	Q13976	PRKG1	S19673	R19669S	19669	Missense	distal	-4	no	8.573	8.103	EPSD	COSMIC	7.092	Down-regulation
AGC_PKG_PRKG1_ST	Q8WZ42	TTN	Q13976	PRKG1	S19673	P19677Q	19677	Missense	distal	4	no	8.573	8.446	EPSD	COSMIC	7.092	Down-regulation
AGC_PKG_PRKG1_ST	Q8WZ42	TTN	Q13976	PRKG1	S19683	P19677Q	19677	Missense	distal	-6	no	9.216	9.531	EPSD	COSMIC	7.092	Up-regulation
AGC_PKG_PRKG1_ST	Q8WZ42	TTN	Q13976	PRKG1	S19683	H19685Y	19685	Missense	proximal	2	no	9.216	9.178	EPSD	COSMIC	7.092	Down-regulation
AGC_PKG_PRKG1_ST	Q8WZ42	TTN	Q13976	PRKG1	S19741	M19737I	19737	Missense	distal	-4	no	8.112	7.406	EPSD	COSMIC	7.092	Down-regulation
AGC_PKG_PRKG1_ST	Q8WZ42	TTN	Q13976	PRKG1	S19741	T19743P	19743	Missense	proximal	2	no	8.112	8.045	EPSD	COSMIC	7.092	Down-regulation
AGC_PKG_PRKG1_ST	Q8WZ42	TTN	Q13976	PRKG1	S19809	G19807R	19807	Missense	proximal	-2	no	5.707	9.194	EPSD	COSMIC	7.092	Gain
AGC_PKG_PRKG1_ST	Q8WZ42	TTN	Q13976	PRKG1	S19879	S19880Y	19880	Missense	proximal	1	no	7.818	7.516	EPSD	COSMIC	7.092	Down-regulation
AGC_PKG_PRKG1_ST	Q8WZ42	TTN	Q13976	PRKG1	S19879	S19879I	19879	Missense	central	0	yes	7.818	0.000	EPSD	COSMIC	7.092	Loss
AGC_PKG_PRKG1_ST	Q8WZ42	TTN	Q13976	PRKG1	S19893	K19891N	19891	Missense	proximal	-2	no	12.669	9.726	EPSD	COSMIC	7.092	Down-regulation
AGC_PKG_PRKG1_ST	Q8WZ42	TTN	Q13976	PRKG1	S19893	R19890W	19890	Missense	distal	-3	no	12.669	4.997	EPSD	COSMIC	7.092	Loss
AGC_PKG_PRKG1_ST	Q8WZ42	TTN	Q13976	PRKG1	S19893	D19887G	19887	Missense	distal	-6	no	12.669	12.944	EPSD	COSMIC	7.092	Up-regulation
AGC_PKG_PRKG1_ST	Q8WZ42	TTN	Q13976	PRKG1	S19893	Y19895F	19895	Missense	proximal	2	no	12.669	12.684	EPSD	COSMIC	7.092	Up-regulation
AGC_PKG_PRKG1_ST	Q8WZ42	TTN	Q13976	PRKG1	S19893	V19888G	19888	Missense	distal	-5	no	12.669	12.632	EPSD	COSMIC	7.092	Down-regulation
AGC_PKG_PRKG1_ST	Q8WZ42	TTN	Q13976	PRKG1	S20101	G20100R	20100	Missense	proximal	-1	no	6.961	7.126	EPSD	COSMIC	7.092	Gain
AGC_PKG_PRKG1_ST	Q8WZ42	TTN	Q13976	PRKG1	S20101	K20098R	20098	Missense	distal	-3	no	6.961	9.319	EPSD	COSMIC	7.092	Gain
AGC_PKG_PRKG1_ST	Q8WZ42	TTN	Q13976	PRKG1	S20102	G20100R	20100	Missense	proximal	-2	no	4.896	8.384	EPSD	COSMIC	7.092	Gain
AGC_PKG_PRKG1_ST	Q8WZ42	TTN	Q13976	PRKG1	T20307	S20301G	20301	Missense	distal	-6	no	8.337	8.119	EPSD	COSMIC	7.092	Down-regulation
AGC_PKG_PRKG1_ST	Q8WZ42	TTN	Q13976	PRKG1	T20307	T20307A	20307	Missense	central	0	yes	8.337	0.000	EPSD	COSMIC	7.092	Loss
AGC_PKG_PRKG1_ST	Q8WZ42	TTN	Q13976	PRKG1	T20307	D20314G	20314	Missense	distal	7	no	8.337	8.366	EPSD	COSMIC	7.092	Up-regulation
AGC_PKG_PRKG1_ST	Q8WZ42	TTN	Q13976	PRKG1	S20501	P20500L	20500	Missense	proximal	-1	no	7.267	7.170	EPSD	COSMIC	7.092	Down-regulation
AGC_PKG_PRKG1_ST	Q8WZ42	TTN	Q13976	PRKG1	S20559	C20565S	20565	Missense	distal	6	no	9.725	9.546	EPSD	COSMIC	7.092	Down-regulation
AGC_PKG_PRKG1_ST	Q8WZ42	TTN	Q13976	PRKG1	S20559	V20563D	20563	Missense	distal	4	no	9.725	9.699	EPSD	COSMIC	7.092	Down-regulation
AGC_PKG_PRKG1_ST	Q8WZ42	TTN	Q13976	PRKG1	T20637	G20635R	20635	Missense	proximal	-2	no	4.333	7.820	EPSD	COSMIC	7.092	Gain
AGC_PKG_PRKG1_ST	Q8WZ42	TTN	Q13976	PRKG1	S20759	E20756Q	20756	Missense	distal	-3	no	8.049	11.155	EPSD	COSMIC	7.092	Up-regulation
AGC_PKG_PRKG1_ST	Q8WZ42	TTN	Q13976	PRKG1	S20761	E20756Q	20756	Missense	distal	-5	no	8.369	8.216	EPSD	COSMIC	7.092	Down-regulation
AGC_PKG_PRKG1_ST	Q8WZ42	TTN	Q13976	PRKG1	S20826	S20825A	20825	Missense	proximal	-1	no	7.259	7.253	EPSD	COSMIC	7.092	Down-regulation
AGC_PKG_PRKG1_ST	Q8WZ42	TTN	Q13976	PRKG1	S20826	S20821F	20821	Missense	distal	-5	no	7.259	7.364	EPSD	COSMIC	7.092	Up-regulation
AGC_PKG_PRKG1_ST	Q8WZ42	TTN	Q13976	PRKG1	S20826	R20820S	20820	Missense	distal	-6	no	7.259	6.962	EPSD	COSMIC	7.092	Loss
AGC_PKG_PRKG1_ST	Q8WZ42	TTN	Q13976	PRKG1	S20826	V20822I	20822	Missense	distal	-4	no	7.259	6.950	EPSD	COSMIC	7.092	Loss
AGC_PKG_PRKG1_ST	Q8WZ42	TTN	Q13976	PRKG1	S20826	S20828L	20828	Missense	proximal	2	no	7.259	7.116	EPSD	COSMIC	7.092	Down-regulation
AGC_PKG_PRKG1_ST	Q8WZ42	TTN	Q13976	PRKG1	S20864	S20864N	20864	Missense	central	0	yes	7.755	0.000	EPSD	COSMIC	7.092	Loss
AGC_PKG_PRKG1_ST	Q8WZ42	TTN	Q13976	PRKG1	S20864	L20865P	20865	Missense	proximal	1	no	7.755	7.985	EPSD	COSMIC	7.092	Up-regulation
AGC_PKG_PRKG1_ST	Q8WZ42	TTN	Q13976	PRKG1	S20868	L20865P	20865	Missense	distal	-3	no	6.620	8.862	EPSD	COSMIC	7.092	Gain
AGC_PKG_PRKG1_ST	Q8WZ42	TTN	Q13976	PRKG1	T20994	E20992K	20992	Missense	proximal	-2	no	4.649	8.172	EPSD	COSMIC	7.092	Gain
AGC_PKG_PRKG1_ST	Q8WZ42	TTN	Q13976	PRKG1	S21045	R21043M	21043	Missense	proximal	-2	no	9.991	6.728	EPSD	COSMIC	7.092	Loss
AGC_PKG_PRKG1_ST	Q8WZ42	TTN	Q13976	PRKG1	S21045	I21039V	21039	Missense	distal	-6	no	9.991	10.247	EPSD	COSMIC	7.092	Up-regulation
AGC_PKG_PRKG1_ST	Q8WZ42	TTN	Q13976	PRKG1	S21045	T21052A	21052	Missense	distal	7	no	9.991	9.981	EPSD	COSMIC	7.092	Down-regulation
AGC_PKG_PRKG1_ST	Q8WZ42	TTN	Q13976	PRKG1	S21045	T21052K	21052	Missense	distal	7	no	9.991	9.999	EPSD	COSMIC	7.092	Up-regulation
AGC_PKG_PRKG1_ST	Q8WZ42	TTN	Q13976	PRKG1	S21290	S21288R	21288	Missense	proximal	-2	no	5.447	8.855	EPSD	COSMIC	7.092	Gain
AGC_PKG_PRKG1_ST	Q8WZ42	TTN	Q13976	PRKG1	S21361	S21361Y	21361	Missense	central	0	yes	7.103	0.000	EPSD	COSMIC;CCLE	7.092	Loss
AGC_PKG_PRKG1_ST	Q8WZ42	TTN	Q13976	PRKG1	S21361	P21359L	21359	Missense	proximal	-2	no	7.103	5.568	EPSD	COSMIC	7.092	Loss
AGC_PKG_PRKG1_ST	Q8WZ42	TTN	Q13976	PRKG1	S21604	G21601R	21601	Missense	distal	-3	no	4.887	9.477	EPSD	COSMIC;CCLE	7.092	Gain
AGC_PKG_PRKG1_ST	Q8WZ42	TTN	Q13976	PRKG1	T21769	E21763Q	21763	Missense	distal	-6	no	6.819	7.168	EPSD	COSMIC	7.092	Gain
AGC_PKG_PRKG1_ST	Q8WZ42	TTN	Q13976	PRKG1	S21840	K21847E	21847	Missense	distal	7	no	10.089	10.005	EPSD	COSMIC	7.092	Down-regulation
AGC_PKG_PRKG1_ST	Q8WZ42	TTN	Q13976	PRKG1	S21840	T21845I	21845	Missense	distal	5	no	10.089	9.993	EPSD	COSMIC	7.092	Down-regulation
AGC_PKG_PRKG1_ST	Q8WZ42	TTN	Q13976	PRKG1	S21840	R21838P	21838	Missense	proximal	-2	no	10.089	6.330	EPSD	COSMIC	7.092	Loss
AGC_PKG_PRKG1_ST	Q8WZ42	TTN	Q13976	PRKG1	S21840	S21840C	21840	Missense	central	0	yes	10.089	0.000	EPSD	COSMIC	7.092	Loss
AGC_PKG_PRKG1_ST	Q8WZ42	TTN	Q13976	PRKG1	S21840	S21842A	21842	Missense	proximal	2	no	10.089	10.064	EPSD	COSMIC	7.092	Down-regulation
AGC_PKG_PRKG1_ST	Q8WZ42	TTN	Q13976	PRKG1	S21840	A21844T	21844	Missense	distal	4	no	10.089	10.092	EPSD	COSMIC	7.092	Up-regulation
AGC_PKG_PRKG1_ST	Q8WZ42	TTN	Q13976	PRKG1	S21842	K21847E	21847	Missense	distal	5	no	8.314	8.251	EPSD	COSMIC	7.092	Down-regulation
AGC_PKG_PRKG1_ST	Q8WZ42	TTN	Q13976	PRKG1	S21842	T21845I	21845	Missense	distal	3	no	8.314	8.641	EPSD	COSMIC	7.092	Up-regulation
AGC_PKG_PRKG1_ST	Q8WZ42	TTN	Q13976	PRKG1	S21842	R21838P	21838	Missense	distal	-4	no	8.314	7.421	EPSD	COSMIC	7.092	Down-regulation
AGC_PKG_PRKG1_ST	Q8WZ42	TTN	Q13976	PRKG1	S21842	S21840C	21840	Missense	proximal	-2	no	8.314	6.993	EPSD	COSMIC	7.092	Loss
AGC_PKG_PRKG1_ST	Q8WZ42	TTN	Q13976	PRKG1	S21842	S21842A	21842	Missense	central	0	yes	8.314	0.000	EPSD	COSMIC	7.092	Loss
AGC_PKG_PRKG1_ST	Q8WZ42	TTN	Q13976	PRKG1	S21842	A21844T	21844	Missense	proximal	2	no	8.314	8.307	EPSD	COSMIC	7.092	Down-regulation
AGC_PKG_PRKG1_ST	Q8WZ42	TTN	Q13976	PRKG1	S22060	P22062L	22062	Missense	proximal	2	no	7.662	7.618	EPSD	COSMIC	7.092	Down-regulation
AGC_PKG_PRKG1_ST	Q8WZ42	TTN	Q13976	PRKG1	S22060	D22059N	22059	Missense	proximal	-1	no	7.662	7.739	EPSD	COSMIC	7.092	Up-regulation
AGC_PKG_PRKG1_ST	Q8WZ42	TTN	Q13976	PRKG1	T22152	A22147V	22147	Missense	distal	-5	no	7.016	7.140	EPSD	COSMIC	7.092	Gain
AGC_PKG_PRKG1_ST	Q8WZ42	TTN	Q13976	PRKG1	S22456	R22454K	22454	Missense	proximal	-2	no	14.351	12.874	EPSD	COSMIC	7.092	Down-regulation
AGC_PKG_PRKG1_ST	Q8WZ42	TTN	Q13976	PRKG1	S22456	G22457C	22457	Missense	proximal	1	no	14.351	14.267	EPSD	COSMIC	7.092	Down-regulation
AGC_PKG_PRKG1_ST	Q8WZ42	TTN	Q13976	PRKG1	S22456	S22456L	22456	Missense	central	0	yes	14.351	0.000	EPSD	COSMIC	7.092	Loss
AGC_PKG_PRKG1_ST	Q8WZ42	TTN	Q13976	PRKG1	S22742	P22735T	22735	Missense	distal	-7	no	6.629	7.183	EPSD	COSMIC	7.092	Gain
AGC_PKG_PRKG1_ST	Q8WZ42	TTN	Q13976	PRKG1	S22828	G22826R	22826	Missense	proximal	-2	no	4.229	7.716	EPSD	COSMIC	7.092	Gain
AGC_PKG_PRKG1_ST	Q8WZ42	TTN	Q13976	PRKG1	S22853	I22857T	22857	Missense	distal	4	no	9.328	9.130	EPSD	COSMIC	7.092	Down-regulation
AGC_PKG_PRKG1_ST	Q8WZ42	TTN	Q13976	PRKG1	S22853	N22847S	22847	Missense	distal	-6	no	9.328	9.609	EPSD	COSMIC	7.092	Up-regulation
AGC_PKG_PRKG1_ST	Q8WZ42	TTN	Q13976	PRKG1	S22853	D22852G	22852	Missense	proximal	-1	no	9.328	9.426	EPSD	COSMIC	7.092	Up-regulation
AGC_PKG_PRKG1_ST	Q8WZ42	TTN	Q13976	PRKG1	S22853	L22858F	22858	Missense	distal	5	no	9.328	9.397	EPSD	COSMIC	7.092	Up-regulation
AGC_PKG_PRKG1_ST	Q8WZ42	TTN	Q13976	PRKG1	S22853	G22846E	22846	Missense	distal	-7	no	9.328	9.010	EPSD	COSMIC	7.092	Down-regulation
AGC_PKG_PRKG1_ST	Q8WZ42	TTN	Q13976	PRKG1	S22853	F22851L	22851	Missense	proximal	-2	no	9.328	8.204	EPSD	COSMIC;CCLE	7.092	Down-regulation
AGC_PKG_PRKG1_ST	Q8WZ42	TTN	Q13976	PRKG1	S22894	T22891K	22891	Missense	distal	-3	no	6.253	9.061	EPSD	COSMIC	7.092	Gain
AGC_PKG_PRKG1_ST	Q8WZ42	TTN	Q13976	PRKG1	S22926	S22920T	22920	Missense	distal	-6	no	8.516	8.432	EPSD	COSMIC	7.092	Down-regulation
AGC_PKG_PRKG1_ST	Q8WZ42	TTN	Q13976	PRKG1	S23063	P23065T	23065	Missense	proximal	2	no	8.370	8.437	EPSD	COSMIC	7.092	Up-regulation
AGC_PKG_PRKG1_ST	Q8WZ42	TTN	Q13976	PRKG1	S23063	V23066M	23066	Missense	distal	3	no	8.370	8.180	EPSD	COSMIC	7.092	Down-regulation
AGC_PKG_PRKG1_ST	Q8WZ42	TTN	Q13976	PRKG1	S23063	P23065S	23065	Missense	proximal	2	no	8.370	8.468	EPSD	COSMIC	7.092	Up-regulation
AGC_PKG_PRKG1_ST	Q8WZ42	TTN	Q13976	PRKG1	S23130	E23127K	23127	Missense	distal	-3	no	2.942	7.525	EPSD	COSMIC	7.092	Gain
AGC_PKG_PRKG1_ST	Q8WZ42	TTN	Q13976	PRKG1	T23210	T23210A	23210	Missense	central	0	yes	8.444	0.000	EPSD	COSMIC	7.092	Loss
AGC_PKG_PRKG1_ST	Q8WZ42	TTN	Q13976	PRKG1	T23210	W23215C	23215	Missense	distal	5	no	8.444	8.475	EPSD	COSMIC	7.092	Up-regulation
AGC_PKG_PRKG1_ST	Q8WZ42	TTN	Q13976	PRKG1	T23226	A23223T	23223	Missense	distal	-3	no	7.298	6.711	EPSD	COSMIC	7.092	Loss
AGC_PKG_PRKG1_ST	Q8WZ42	TTN	Q13976	PRKG1	T23226	I23227V	23227	Missense	proximal	1	no	7.298	7.427	EPSD	COSMIC	7.092	Up-regulation
AGC_PKG_PRKG1_ST	Q8WZ42	TTN	Q13976	PRKG1	T23226	A23229V	23229	Missense	distal	3	no	7.298	7.500	EPSD	COSMIC	7.092	Up-regulation
AGC_PKG_PRKG1_ST	Q8WZ42	TTN	Q13976	PRKG1	T23226	R23224K	23224	Missense	proximal	-2	no	7.298	5.821	EPSD	COSMIC	7.092	Loss
AGC_PKG_PRKG1_ST	Q8WZ42	TTN	Q13976	PRKG1	T23226	K23233E	23233	Missense	distal	7	no	7.298	7.214	EPSD	COSMIC	7.092	Down-regulation
AGC_PKG_PRKG1_ST	Q8WZ42	TTN	Q13976	PRKG1	T23226	A23223V	23223	Missense	distal	-3	no	7.298	6.196	EPSD	COSMIC	7.092	Loss
AGC_PKG_PRKG1_ST	Q8WZ42	TTN	Q13976	PRKG1	S23381	T23378A	23378	Missense	distal	-3	no	7.465	8.052	EPSD	COSMIC	7.092	Up-regulation
AGC_PKG_PRKG1_ST	Q8WZ42	TTN	Q13976	PRKG1	S23381	L23384R	23384	Missense	distal	3	no	7.465	7.031	EPSD	COSMIC	7.092	Loss
AGC_PKG_PRKG1_ST	Q8WZ42	TTN	Q13976	PRKG1	S23381	R23379K	23379	Missense	proximal	-2	no	7.465	5.987	EPSD	COSMIC	7.092	Loss
AGC_PKG_PRKG1_ST	Q8WZ42	TTN	Q13976	PRKG1	T23390	L23384R	23384	Missense	distal	-6	no	6.706	7.630	EPSD	COSMIC	7.092	Gain
AGC_PKG_PRKG1_ST	Q8WZ42	TTN	Q13976	PRKG1	S23471	D23473H	23473	Missense	proximal	2	no	7.287	7.319	EPSD	COSMIC	7.092	Up-regulation
AGC_PKG_PRKG1_ST	Q8WZ42	TTN	Q13976	PRKG1	S23471	D23478N	23478	Missense	distal	7	no	7.287	7.330	EPSD	COSMIC	7.092	Up-regulation
AGC_PKG_PRKG1_ST	Q8WZ42	TTN	Q13976	PRKG1	S23471	D23473Y	23473	Missense	proximal	2	no	7.287	7.281	EPSD	COSMIC	7.092	Down-regulation
AGC_PKG_PRKG1_ST	Q8WZ42	TTN	Q13976	PRKG1	S23553	E23551Q	23551	Missense	proximal	-2	no	5.927	7.962	EPSD	COSMIC	7.092	Gain
AGC_PKG_PRKG1_ST	Q8WZ42	TTN	Q13976	PRKG1	T23555	E23551Q	23551	Missense	distal	-4	no	8.643	9.213	EPSD	COSMIC	7.092	Up-regulation
AGC_PKG_PRKG1_ST	Q8WZ42	TTN	Q13976	PRKG1	T23555	S23553F	23553	Missense	proximal	-2	no	8.643	7.881	EPSD	COSMIC	7.092	Down-regulation
AGC_PKG_PRKG1_ST	Q8WZ42	TTN	Q13976	PRKG1	T23555	T23555A	23555	Missense	central	0	yes	8.643	0.000	EPSD	COSMIC	7.092	Loss
AGC_PKG_PRKG1_ST	Q8WZ42	TTN	Q13976	PRKG1	T23555	R23552I	23552	Missense	distal	-3	no	8.643	0.137	EPSD	COSMIC	7.092	Loss
AGC_PKG_PRKG1_ST	Q8WZ42	TTN	Q13976	PRKG1	T23555	D23562E	23562	Missense	distal	7	no	8.643	8.657	EPSD	COSMIC	7.092	Up-regulation
AGC_PKG_PRKG1_ST	Q8WZ42	TTN	Q13976	PRKG1	T23555	K23559N	23559	Missense	distal	4	no	8.643	8.719	EPSD	COSMIC	7.092	Up-regulation
AGC_PKG_PRKG1_ST	Q8WZ42	TTN	Q13976	PRKG1	T23898	W23903R	23903	Missense	distal	5	no	8.004	8.104	EPSD	COSMIC	7.092	Up-regulation
AGC_PKG_PRKG1_ST	Q8WZ42	TTN	Q13976	PRKG1	T23898	G23895V	23895	Missense	distal	-3	no	8.004	6.913	EPSD	COSMIC	7.092	Loss
AGC_PKG_PRKG1_ST	Q8WZ42	TTN	Q13976	PRKG1	T23939	D23934N	23934	Missense	distal	-5	no	7.554	7.472	EPSD	COSMIC	7.092	Down-regulation
AGC_PKG_PRKG1_ST	Q8WZ42	TTN	Q13976	PRKG1	T23939	T23939K	23939	Missense	central	0	yes	7.554	0.000	EPSD	COSMIC	7.092	Loss
AGC_PKG_PRKG1_ST	Q8WZ42	TTN	Q13976	PRKG1	T23939	S23946F	23946	Missense	distal	7	no	7.554	7.479	EPSD	COSMIC	7.092	Down-regulation
AGC_PKG_PRKG1_ST	Q8WZ42	TTN	Q13976	PRKG1	T23939	L23940H	23940	Missense	proximal	1	no	7.554	7.885	EPSD	COSMIC	7.092	Up-regulation
AGC_PKG_PRKG1_ST	Q8WZ42	TTN	Q13976	PRKG1	S24006	V24010I	24010	Missense	distal	4	no	9.473	9.534	EPSD	COSMIC	7.092	Up-regulation
AGC_PKG_PRKG1_ST	Q8WZ42	TTN	Q13976	PRKG1	S24105	E24102K	24102	Missense	distal	-3	no	5.521	10.104	EPSD	COSMIC	7.092	Gain
AGC_PKG_PRKG1_ST	Q8WZ42	TTN	Q13976	PRKG1	S24112	L24113I	24113	Missense	proximal	1	no	10.058	10.086	EPSD	COSMIC	7.092	Up-regulation
AGC_PKG_PRKG1_ST	Q8WZ42	TTN	Q13976	PRKG1	S24112	L24113P	24113	Missense	proximal	1	no	10.058	10.289	EPSD	COSMIC	7.092	Up-regulation
AGC_PKG_PRKG1_ST	Q8WZ42	TTN	Q13976	PRKG1	S24167	S24167Y	24167	Missense	central	0	yes	7.230	0.000	EPSD	COSMIC	7.092	Loss
AGC_PKG_PRKG1_ST	Q8WZ42	TTN	Q13976	PRKG1	S24167	K24160E	24160	Missense	distal	-7	no	7.230	6.229	EPSD	COSMIC	7.092	Loss
AGC_PKG_PRKG1_ST	Q8WZ42	TTN	Q13976	PRKG1	S24167	P24161H	24161	Missense	distal	-6	no	7.230	7.318	EPSD	COSMIC	7.092	Up-regulation
AGC_PKG_PRKG1_ST	Q8WZ42	TTN	Q13976	PRKG1	S24241	T24246I	24246	Missense	distal	5	no	8.524	8.428	EPSD	COSMIC	7.092	Down-regulation
AGC_PKG_PRKG1_ST	Q8WZ42	TTN	Q13976	PRKG1	S24241	T24239K	24239	Missense	proximal	-2	no	8.524	10.639	EPSD	COSMIC	7.092	Up-regulation
AGC_PKG_PRKG1_ST	Q8WZ42	TTN	Q13976	PRKG1	S24635	S24628Y	24628	Missense	distal	-7	no	8.010	7.220	EPSD	COSMIC;CCLE	7.092	Down-regulation
AGC_PKG_PRKG1_ST	Q8WZ42	TTN	Q13976	PRKG1	S24635	N24629S	24629	Missense	distal	-6	no	8.010	8.291	EPSD	COSMIC	7.092	Up-regulation
AGC_PKG_PRKG1_ST	Q8WZ42	TTN	Q13976	PRKG1	S24635	K24641N	24641	Missense	distal	6	no	8.010	8.164	EPSD	COSMIC	7.092	Up-regulation
AGC_PKG_PRKG1_ST	Q8WZ42	TTN	Q13976	PRKG1	S24635	S24633Y	24633	Missense	proximal	-2	no	8.010	7.321	EPSD	COSMIC	7.092	Down-regulation
AGC_PKG_PRKG1_ST	Q8WZ42	TTN	Q13976	PRKG1	S24635	V24642L	24642	Missense	distal	7	no	8.010	7.936	EPSD	COSMIC	7.092	Down-regulation
AGC_PKG_PRKG1_ST	Q8WZ42	TTN	Q13976	PRKG1	S24635	K24641E	24641	Missense	distal	6	no	8.010	8.227	EPSD	COSMIC	7.092	Up-regulation
AGC_PKG_PRKG1_ST	Q8WZ42	TTN	Q13976	PRKG1	T24688	A24692V	24692	Missense	distal	4	no	9.393	9.532	EPSD	COSMIC	7.092	Up-regulation
AGC_PKG_PRKG1_ST	Q8WZ42	TTN	Q13976	PRKG1	T24688	S24689I	24689	Missense	proximal	1	no	9.393	8.928	EPSD	COSMIC	7.092	Down-regulation
AGC_PKG_PRKG1_ST	Q8WZ42	TTN	Q13976	PRKG1	T24688	A24692T	24692	Missense	distal	4	no	9.393	9.395	EPSD	COSMIC	7.092	Up-regulation
AGC_PKG_PRKG1_ST	Q8WZ42	TTN	Q13976	PRKG1	S24689	A24692V	24692	Missense	distal	3	no	7.156	7.358	EPSD	COSMIC	7.092	Up-regulation
AGC_PKG_PRKG1_ST	Q8WZ42	TTN	Q13976	PRKG1	S24689	S24689I	24689	Missense	central	0	yes	7.156	0.000	EPSD	COSMIC	7.092	Loss
AGC_PKG_PRKG1_ST	Q8WZ42	TTN	Q13976	PRKG1	S24689	A24692T	24692	Missense	distal	3	no	7.156	7.124	EPSD	COSMIC	7.092	Down-regulation
AGC_PKG_PRKG1_ST	Q8WZ42	TTN	Q13976	PRKG1	S24761	D24760N	24760	Missense	proximal	-1	no	7.855	7.932	EPSD	COSMIC	7.092	Up-regulation
AGC_PKG_PRKG1_ST	Q8WZ42	TTN	Q13976	PRKG1	S24788	G24789R	24789	Missense	proximal	1	no	7.034	7.398	EPSD	COSMIC	7.092	Gain
AGC_PKG_PRKG1_ST	Q8WZ42	TTN	Q13976	PRKG1	S24788	C24795R	24795	Missense	distal	7	no	7.034	7.146	EPSD	COSMIC	7.092	Gain
AGC_PKG_PRKG1_ST	Q8WZ42	TTN	Q13976	PRKG1	T24801	R24806H	24806	Missense	distal	5	no	11.912	11.863	EPSD	COSMIC	7.092	Down-regulation
AGC_PKG_PRKG1_ST	Q8WZ42	TTN	Q13976	PRKG1	T24801	R24806C	24806	Missense	distal	5	no	11.912	11.843	EPSD	COSMIC	7.092	Down-regulation
AGC_PKG_PRKG1_ST	Q8WZ42	TTN	Q13976	PRKG1	T24801	R24799C	24799	Missense	proximal	-2	no	11.912	7.184	EPSD	COSMIC	7.092	Down-regulation
AGC_PKG_PRKG1_ST	Q8WZ42	TTN	Q13976	PRKG1	T24801	R24804C	24804	Missense	distal	3	no	11.912	12.135	EPSD	COSMIC	7.092	Up-regulation
AGC_PKG_PRKG1_ST	Q8WZ42	TTN	Q13976	PRKG1	T24801	C24795R	24795	Missense	distal	-6	no	11.912	12.581	EPSD	COSMIC	7.092	Up-regulation
AGC_PKG_PRKG1_ST	Q8WZ42	TTN	Q13976	PRKG1	T24801	K24797N	24797	Missense	distal	-4	no	11.912	11.375	EPSD	COSMIC	7.092	Down-regulation
AGC_PKG_PRKG1_ST	Q8WZ42	TTN	Q13976	PRKG1	S24935	E24932K	24932	Missense	distal	-3	no	2.801	7.384	EPSD	COSMIC	7.092	Gain
AGC_PKG_PRKG1_ST	Q8WZ42	TTN	Q13976	PRKG1	S25097	S25094L	25094	Missense	distal	-3	no	7.575	5.920	EPSD	COSMIC	7.092	Loss
AGC_PKG_PRKG1_ST	Q8WZ42	TTN	Q13976	PRKG1	S25097	A25090P	25090	Missense	distal	-7	no	7.575	6.967	EPSD	COSMIC	7.092	Loss
AGC_PKG_PRKG1_ST	Q8WZ42	TTN	Q13976	PRKG1	S25097	K25098N	25098	Missense	proximal	1	no	7.575	7.325	EPSD	COSMIC	7.092	Down-regulation
AGC_PKG_PRKG1_ST	Q8WZ42	TTN	Q13976	PRKG1	S25097	C25096Y	25096	Missense	proximal	-1	no	7.575	7.584	EPSD	COSMIC	7.092	Up-regulation
AGC_PKG_PRKG1_ST	Q8WZ42	TTN	Q13976	PRKG1	T25374	K25371N	25371	Missense	distal	-3	no	8.716	4.169	EPSD	COSMIC	7.092	Loss
AGC_PKG_PRKG1_ST	Q8WZ42	TTN	Q13976	PRKG1	T25374	T25376A	25376	Missense	proximal	2	no	8.716	8.723	EPSD	COSMIC	7.092	Up-regulation
AGC_PKG_PRKG1_ST	Q8WZ42	TTN	Q13976	PRKG1	T25374	M25381I	25381	Missense	distal	7	no	8.716	8.585	EPSD	COSMIC	7.092	Down-regulation
AGC_PKG_PRKG1_ST	Q8WZ42	TTN	Q13976	PRKG1	T25374	H25380L	25380	Missense	distal	6	no	8.716	8.971	EPSD	COSMIC	7.092	Up-regulation
AGC_PKG_PRKG1_ST	Q8WZ42	TTN	Q13976	PRKG1	T25374	R25372P	25372	Missense	proximal	-2	no	8.716	4.957	EPSD	COSMIC	7.092	Loss
AGC_PKG_PRKG1_ST	Q8WZ42	TTN	Q13976	PRKG1	T26230	G26227R	26227	Missense	distal	-3	no	5.805	10.395	EPSD	COSMIC	7.092	Gain
AGC_PKG_PRKG1_ST	Q8WZ42	TTN	Q13976	PRKG1	S26248	E26247D	26247	Missense	proximal	-1	no	7.560	7.518	EPSD	COSMIC	7.092	Down-regulation
AGC_PKG_PRKG1_ST	Q8WZ42	TTN	Q13976	PRKG1	S26248	G26251D	26251	Missense	distal	3	no	7.560	7.603	EPSD	COSMIC	7.092	Up-regulation
AGC_PKG_PRKG1_ST	Q8WZ42	TTN	Q13976	PRKG1	S26248	S26252Y	26252	Missense	distal	4	no	7.560	7.710	EPSD	COSMIC	7.092	Up-regulation
AGC_PKG_PRKG1_ST	Q8WZ42	TTN	Q13976	PRKG1	S26266	G26265R	26265	Missense	proximal	-1	no	7.090	7.254	EPSD	COSMIC	7.092	Gain
AGC_PKG_PRKG1_ST	Q8WZ42	TTN	Q13976	PRKG1	T26404	G26401R	26401	Missense	distal	-3	no	3.644	8.234	EPSD	COSMIC	7.092	Gain
AGC_PKG_PRKG1_ST	Q8WZ42	TTN	Q13976	PRKG1	S26458	E26455K	26455	Missense	distal	-3	no	4.409	8.992	EPSD	COSMIC	7.092	Gain
AGC_PKG_PRKG1_ST	Q8WZ42	TTN	Q13976	PRKG1	S26472	A26467T	26467	Missense	distal	-5	no	9.482	9.492	EPSD	COSMIC	7.092	Up-regulation
AGC_PKG_PRKG1_ST	Q8WZ42	TTN	Q13976	PRKG1	S26472	R26477C	26477	Missense	distal	5	no	9.482	9.412	EPSD	COSMIC	7.092	Down-regulation
AGC_PKG_PRKG1_ST	Q8WZ42	TTN	Q13976	PRKG1	S26472	I26475T	26475	Missense	distal	3	no	9.482	9.155	EPSD	COSMIC	7.092	Down-regulation
AGC_PKG_PRKG1_ST	Q8WZ42	TTN	Q13976	PRKG1	S26472	A26469D	26469	Missense	distal	-3	no	9.482	5.573	EPSD	COSMIC	7.092	Loss
AGC_PKG_PRKG1_ST	Q8WZ42	TTN	Q13976	PRKG1	S26576	E26580K	26580	Missense	distal	4	no	8.943	8.828	EPSD	COSMIC	7.092	Down-regulation
AGC_PKG_PRKG1_ST	Q8WZ42	TTN	Q13976	PRKG1	S26576	M26573V	26573	Missense	distal	-3	no	8.943	8.567	EPSD	COSMIC	7.092	Down-regulation
AGC_PKG_PRKG1_ST	Q8WZ42	TTN	Q13976	PRKG1	S26576	L26582V	26582	Missense	distal	6	no	8.943	8.808	EPSD	COSMIC;CCLE	7.092	Down-regulation
AGC_PKG_PRKG1_ST	Q8WZ42	TTN	Q13976	PRKG1	S26576	G26581E	26581	Missense	distal	5	no	8.943	8.938	EPSD	COSMIC	7.092	Down-regulation
AGC_PKG_PRKG1_ST	Q8WZ42	TTN	Q13976	PRKG1	S26576	M26573L	26573	Missense	distal	-3	no	8.943	7.103	EPSD	COSMIC	7.092	Down-regulation
AGC_PKG_PRKG1_ST	Q8WZ42	TTN	Q13976	PRKG1	S26576	D26570N	26570	Missense	distal	-6	no	8.943	9.154	EPSD	COSMIC	7.092	Up-regulation
AGC_PKG_PRKG1_ST	Q8WZ42	TTN	Q13976	PRKG1	S26576	M26583I	26583	Missense	distal	7	no	8.943	8.813	EPSD	COSMIC	7.092	Down-regulation
AGC_PKG_PRKG1_ST	Q8WZ42	TTN	Q13976	PRKG1	S26629	S26627F	26627	Missense	proximal	-2	no	7.828	7.066	EPSD	COSMIC	7.092	Loss
AGC_PKG_PRKG1_ST	Q8WZ42	TTN	Q13976	PRKG1	S26629	S26627L	26627	Missense	proximal	-2	no	7.828	5.942	EPSD	COSMIC	7.092	Loss
AGC_PKG_PRKG1_ST	Q8WZ42	TTN	Q13976	PRKG1	T26784	L26791P	26791	Missense	distal	7	no	10.269	10.334	EPSD	COSMIC	7.092	Up-regulation
AGC_PKG_PRKG1_ST	Q8WZ42	TTN	Q13976	PRKG1	T26784	R26781S	26781	Missense	distal	-3	no	10.269	4.780	EPSD	COSMIC	7.092	Loss
AGC_PKG_PRKG1_ST	Q8WZ42	TTN	Q13976	PRKG1	T26784	T26790S	26790	Missense	distal	6	no	10.269	10.228	EPSD	COSMIC	7.092	Down-regulation
AGC_PKG_PRKG1_ST	Q8WZ42	TTN	Q13976	PRKG1	T26784	Y26787C	26787	Missense	distal	3	no	10.269	10.235	EPSD	COSMIC	7.092	Down-regulation
AGC_PKG_PRKG1_ST	Q8WZ42	TTN	Q13976	PRKG1	S26799	S26799Y	26799	Missense	central	0	yes	7.502	0.000	EPSD	COSMIC;CCLE	7.092	Loss
AGC_PKG_PRKG1_ST	Q8WZ42	TTN	Q13976	PRKG1	S26799	T26797S	26797	Missense	proximal	-2	no	7.502	7.686	EPSD	COSMIC	7.092	Up-regulation
AGC_PKG_PRKG1_ST	Q8WZ42	TTN	Q13976	PRKG1	S26799	G26796C	26796	Missense	distal	-3	no	7.502	5.070	EPSD	COSMIC	7.092	Loss
AGC_PKG_PRKG1_ST	Q8WZ42	TTN	Q13976	PRKG1	S26971	D26966N	26966	Missense	distal	-5	no	9.189	9.107	EPSD	COSMIC	7.092	Down-regulation
AGC_PKG_PRKG1_ST	Q8WZ42	TTN	Q13976	PRKG1	T27183	Y27182H	27182	Missense	proximal	-1	no	7.087	7.132	EPSD	COSMIC	7.092	Gain
AGC_PKG_PRKG1_ST	Q8WZ42	TTN	Q13976	PRKG1	S27368	F27372S	27372	Missense	distal	4	no	7.477	7.349	EPSD	COSMIC	7.092	Down-regulation
AGC_PKG_PRKG1_ST	Q8WZ42	TTN	Q13976	PRKG1	S27368	E27366K	27366	Missense	proximal	-2	no	7.477	11.000	EPSD	COSMIC	7.092	Up-regulation
AGC_PKG_PRKG1_ST	Q8WZ42	TTN	Q13976	PRKG1	S27867	G27868R	27868	Missense	proximal	1	no	7.364	7.728	EPSD	COSMIC;CCLE	7.092	Up-regulation
AGC_PKG_PRKG1_ST	Q8WZ42	TTN	Q13976	PRKG1	S27867	E27871G	27871	Missense	distal	4	no	7.364	7.354	EPSD	COSMIC	7.092	Down-regulation
AGC_PKG_PRKG1_ST	Q8WZ42	TTN	Q13976	PRKG1	S27867	R27864C	27864	Missense	distal	-3	no	7.364	0.342	EPSD	COSMIC	7.092	Loss
AGC_PKG_PRKG1_ST	Q8WZ42	TTN	Q13976	PRKG1	S27867	A27862T	27862	Missense	distal	-5	no	7.364	7.374	EPSD	COSMIC	7.092	Up-regulation
AGC_PKG_PRKG1_ST	Q8WZ42	TTN	Q13976	PRKG1	S27882	R27886S	27886	Missense	distal	4	no	7.671	7.707	EPSD	COSMIC	7.092	Up-regulation
AGC_PKG_PRKG1_ST	Q8WZ42	TTN	Q13976	PRKG1	S27882	I27889N	27889	Missense	distal	7	no	7.671	7.759	EPSD	COSMIC	7.092	Up-regulation
AGC_PKG_PRKG1_ST	Q8WZ42	TTN	Q13976	PRKG1	S28397	D28395N	28395	Missense	proximal	-2	no	6.568	8.050	EPSD	COSMIC	7.092	Gain
AGC_PKG_PRKG1_ST	Q8WZ42	TTN	Q13976	PRKG1	S28521	G28516E	28516	Missense	distal	-5	no	7.355	7.402	EPSD	COSMIC	7.092	Up-regulation
AGC_PKG_PRKG1_ST	Q8WZ42	TTN	Q13976	PRKG1	S28521	P28518H	28518	Missense	distal	-3	no	7.355	6.190	EPSD	COSMIC	7.092	Loss
AGC_PKG_PRKG1_ST	Q8WZ42	TTN	Q13976	PRKG1	S28540	E28533K	28533	Missense	distal	-7	no	6.962	7.963	EPSD	COSMIC;CCLE	7.092	Gain
AGC_PKG_PRKG1_ST	Q8WZ42	TTN	Q13976	PRKG1	S28627	R28624S	28624	Missense	distal	-3	no	8.326	2.838	EPSD	COSMIC	7.092	Loss
AGC_PKG_PRKG1_ST	Q8WZ42	TTN	Q13976	PRKG1	S28627	Q28628R	28628	Missense	proximal	1	no	8.326	8.490	EPSD	COSMIC	7.092	Up-regulation
AGC_PKG_PRKG1_ST	Q8WZ42	TTN	Q13976	PRKG1	S28627	T28626S	28626	Missense	proximal	-1	no	8.326	8.328	EPSD	COSMIC	7.092	Up-regulation
AGC_PKG_PRKG1_ST	Q8WZ42	TTN	Q13976	PRKG1	S29104	S29108N	29108	Missense	distal	4	no	7.836	7.918	EPSD	COSMIC	7.092	Up-regulation
AGC_PKG_PRKG1_ST	Q8WZ42	TTN	Q13976	PRKG1	S29104	G29106R	29106	Missense	proximal	2	no	7.836	7.895	EPSD	COSMIC	7.092	Up-regulation
AGC_PKG_PRKG1_ST	Q8WZ42	TTN	Q13976	PRKG1	S29104	T29098A	29098	Missense	distal	-6	no	7.836	7.876	EPSD	COSMIC	7.092	Up-regulation
AGC_PKG_PRKG1_ST	Q8WZ42	TTN	Q13976	PRKG1	S29104	G29106S	29106	Missense	proximal	2	no	7.836	7.907	EPSD	COSMIC	7.092	Up-regulation
AGC_PKG_PRKG1_ST	Q8WZ42	TTN	Q13976	PRKG1	S29104	E29109K	29109	Missense	distal	5	no	7.836	7.899	EPSD	COSMIC	7.092	Up-regulation
AGC_PKG_PRKG1_ST	Q8WZ42	TTN	Q13976	PRKG1	T29123	R29124T	29124	Missense	proximal	1	no	7.408	7.182	EPSD	COSMIC	7.092	Down-regulation
AGC_PKG_PRKG1_ST	Q8WZ42	TTN	Q13976	PRKG1	T29123	R29117I	29117	Missense	distal	-6	no	7.408	6.475	EPSD	COSMIC	7.092	Loss
AGC_PKG_PRKG1_ST	Q8WZ42	TTN	Q13976	PRKG1	T29123	E29116Q	29116	Missense	distal	-7	no	7.408	8.198	EPSD	COSMIC	7.092	Up-regulation
AGC_PKG_PRKG1_ST	Q8WZ42	TTN	Q13976	PRKG1	T29123	R29117K	29117	Missense	distal	-6	no	7.408	7.243	EPSD	COSMIC	7.092	Down-regulation
AGC_PKG_PRKG1_ST	Q8WZ42	TTN	Q13976	PRKG1	T29241	A29247P	29247	Missense	distal	6	no	7.593	7.797	EPSD	COSMIC	7.092	Up-regulation
AGC_PKG_PRKG1_ST	Q8WZ42	TTN	Q13976	PRKG1	T29241	A29234T	29234	Missense	distal	-7	no	7.593	7.538	EPSD	COSMIC	7.092	Down-regulation
AGC_PKG_PRKG1_ST	Q8WZ42	TTN	Q13976	PRKG1	S29361	E29358K	29358	Missense	distal	-3	no	2.522	7.105	EPSD	COSMIC	7.092	Gain
AGC_PKG_PRKG1_ST	Q8WZ42	TTN	Q13976	PRKG1	S29421	E29427K	29427	Missense	distal	6	no	10.167	9.950	EPSD	COSMIC	7.092	Down-regulation
AGC_PKG_PRKG1_ST	Q8WZ42	TTN	Q13976	PRKG1	S29421	S29426R	29426	Missense	distal	5	no	10.167	10.189	EPSD	COSMIC	7.092	Up-regulation
AGC_PKG_PRKG1_ST	Q8WZ42	TTN	Q13976	PRKG1	S29516	S29516Y	29516	Missense	central	0	yes	8.744	0.000	EPSD	COSMIC	7.092	Loss
AGC_PKG_PRKG1_ST	Q8WZ42	TTN	Q13976	PRKG1	S29516	K29514N	29514	Missense	proximal	-2	no	8.744	5.800	EPSD	COSMIC	7.092	Loss
AGC_PKG_PRKG1_ST	Q8WZ42	TTN	Q13976	PRKG1	S29516	K29514T	29514	Missense	proximal	-2	no	8.744	6.629	EPSD	COSMIC	7.092	Loss
AGC_PKG_PRKG1_ST	Q8WZ42	TTN	Q13976	PRKG1	S29637	D29636N	29636	Missense	proximal	-1	no	8.108	8.185	EPSD	COSMIC	7.092	Up-regulation
AGC_PKG_PRKG1_ST	Q8WZ42	TTN	Q13976	PRKG1	S29637	G29643E	29643	Missense	distal	6	no	8.108	8.171	EPSD	COSMIC	7.092	Up-regulation
AGC_PKG_PRKG1_ST	Q8WZ42	TTN	Q13976	PRKG1	S29642	D29636N	29636	Missense	distal	-6	no	10.753	10.964	EPSD	COSMIC	7.092	Up-regulation
AGC_PKG_PRKG1_ST	Q8WZ42	TTN	Q13976	PRKG1	S29642	G29643E	29643	Missense	proximal	1	no	10.753	10.682	EPSD	COSMIC	7.092	Down-regulation
AGC_PKG_PRKG1_ST	Q8WZ42	TTN	Q13976	PRKG1	S29642	Y29645H	29645	Missense	distal	3	no	10.753	10.653	EPSD	COSMIC	7.092	Down-regulation
AGC_PKG_PRKG1_ST	Q8WZ42	TTN	Q13976	PRKG1	S29710	G29711S	29711	Missense	proximal	1	no	9.960	10.149	EPSD	COSMIC	7.092	Up-regulation
AGC_PKG_PRKG1_ST	Q8WZ42	TTN	Q13976	PRKG1	S29710	I29704M	29704	Missense	distal	-6	no	9.960	10.480	EPSD	COSMIC	7.092	Up-regulation
AGC_PKG_PRKG1_ST	Q8WZ42	TTN	Q13976	PRKG1	S29710	R29708T	29708	Missense	proximal	-2	no	9.960	6.367	EPSD	COSMIC	7.092	Loss
AGC_PKG_PRKG1_ST	Q8WZ42	TTN	Q13976	PRKG1	S29710	R29708K	29708	Missense	proximal	-2	no	9.960	8.482	EPSD	COSMIC	7.092	Down-regulation
AGC_PKG_PRKG1_ST	Q8WZ42	TTN	Q13976	PRKG1	T30046	K30044E	30044	Missense	proximal	-2	no	7.771	4.248	EPSD	COSMIC	7.092	Loss
AGC_PKG_PRKG1_ST	Q8WZ42	TTN	Q13976	PRKG1	T30046	A30052V	30052	Missense	distal	6	no	7.771	7.967	EPSD	COSMIC	7.092	Up-regulation
AGC_PKG_PRKG1_ST	Q8WZ42	TTN	Q13976	PRKG1	S30125	P30122R	30122	Missense	distal	-3	no	4.024	8.926	EPSD	COSMIC	7.092	Gain
AGC_PKG_PRKG1_ST	Q8WZ42	TTN	Q13976	PRKG1	S30266	S30261A	30261	Missense	distal	-5	no	8.429	8.428	EPSD	COSMIC	7.092	Down-regulation
AGC_PKG_PRKG1_ST	Q8WZ42	TTN	Q13976	PRKG1	S30266	P30269S	30269	Missense	distal	3	no	8.429	8.179	EPSD	COSMIC	7.092	Down-regulation
AGC_PKG_PRKG1_ST	Q8WZ42	TTN	Q13976	PRKG1	S30266	Y30267S	30267	Missense	proximal	1	no	8.429	8.731	EPSD	COSMIC	7.092	Up-regulation
AGC_PKG_PRKG1_ST	Q8WZ42	TTN	Q13976	PRKG1	S30454	L30458P	30458	Missense	distal	4	no	7.944	7.845	EPSD	COSMIC	7.092	Down-regulation
AGC_PKG_PRKG1_ST	Q8WZ42	TTN	Q13976	PRKG1	S30454	K30460E	30460	Missense	distal	6	no	7.944	8.162	EPSD	COSMIC	7.092	Up-regulation
AGC_PKG_PRKG1_ST	Q8WZ42	TTN	Q13976	PRKG1	T30456	D30463N	30463	Missense	distal	7	no	7.502	7.545	EPSD	COSMIC	7.092	Up-regulation
AGC_PKG_PRKG1_ST	Q8WZ42	TTN	Q13976	PRKG1	T30456	L30458P	30458	Missense	proximal	2	no	7.502	7.546	EPSD	COSMIC	7.092	Up-regulation
AGC_PKG_PRKG1_ST	Q8WZ42	TTN	Q13976	PRKG1	T30456	K30460E	30460	Missense	distal	4	no	7.502	7.617	EPSD	COSMIC	7.092	Up-regulation
AGC_PKG_PRKG1_ST	Q8WZ42	TTN	Q13976	PRKG1	S30519	I30525V	30525	Missense	distal	6	no	8.015	7.912	EPSD	COSMIC	7.092	Down-regulation
AGC_PKG_PRKG1_ST	Q8WZ42	TTN	Q13976	PRKG1	T30650	A30653V	30653	Missense	distal	3	no	7.181	7.383	EPSD	COSMIC	7.092	Up-regulation
AGC_PKG_PRKG1_ST	Q8WZ42	TTN	Q13976	PRKG1	S30709	E30710Q	30710	Missense	proximal	1	no	6.968	7.240	EPSD	COSMIC	7.092	Gain
AGC_PKG_PRKG1_ST	Q8WZ42	TTN	Q13976	PRKG1	S30920	G30922A	30922	Missense	proximal	2	no	8.644	8.690	EPSD	COSMIC	7.092	Up-regulation
AGC_PKG_PRKG1_ST	Q8WZ42	TTN	Q13976	PRKG1	S30941	G30940V	30940	Missense	proximal	-1	no	7.539	7.488	EPSD	COSMIC	7.092	Down-regulation
AGC_PKG_PRKG1_ST	Q8WZ42	TTN	Q13976	PRKG1	S30941	R30946C	30946	Missense	distal	5	no	7.539	7.469	EPSD	COSMIC	7.092	Down-regulation
AGC_PKG_PRKG1_ST	Q8WZ42	TTN	Q13976	PRKG1	S30941	R30946H	30946	Missense	distal	5	no	7.539	7.489	EPSD	COSMIC	7.092	Down-regulation
AGC_PKG_PRKG1_ST	Q8WZ42	TTN	Q13976	PRKG1	S30941	T30934P	30934	Missense	distal	-7	no	7.539	6.985	EPSD	COSMIC	7.092	Loss
AGC_PKG_PRKG1_ST	Q8WZ42	TTN	Q13976	PRKG1	S30945	G30940V	30940	Missense	distal	-5	no	8.438	8.475	EPSD	COSMIC	7.092	Up-regulation
AGC_PKG_PRKG1_ST	Q8WZ42	TTN	Q13976	PRKG1	S30945	R30946C	30946	Missense	proximal	1	no	8.438	7.989	EPSD	COSMIC	7.092	Down-regulation
AGC_PKG_PRKG1_ST	Q8WZ42	TTN	Q13976	PRKG1	S30945	R30946H	30946	Missense	proximal	1	no	8.438	8.102	EPSD	COSMIC	7.092	Down-regulation
AGC_PKG_PRKG1_ST	Q8WZ42	TTN	Q13976	PRKG1	S30948	R30946C	30946	Missense	proximal	-2	no	9.420	4.692	EPSD	COSMIC	7.092	Loss
AGC_PKG_PRKG1_ST	Q8WZ42	TTN	Q13976	PRKG1	S30948	R30946H	30946	Missense	proximal	-2	no	9.420	5.163	EPSD	COSMIC	7.092	Loss
AGC_PKG_PRKG1_ST	Q8WZ42	TTN	Q13976	PRKG1	T31020	E31018K	31018	Missense	proximal	-2	no	4.945	8.468	EPSD	COSMIC	7.092	Gain
AGC_PKG_PRKG1_ST	Q8WZ42	TTN	Q13976	PRKG1	S31213	V31216I	31216	Missense	distal	3	no	8.414	8.508	EPSD	COSMIC	7.092	Up-regulation
AGC_PKG_PRKG1_ST	Q8WZ42	TTN	Q13976	PRKG1	S31449	L31454I	31454	Missense	distal	5	no	7.134	7.150	EPSD	COSMIC	7.092	Up-regulation
AGC_PKG_PRKG1_ST	Q8WZ42	TTN	Q13976	PRKG1	S31449	R31444C	31444	Missense	distal	-5	no	7.134	7.391	EPSD	COSMIC	7.092	Up-regulation
AGC_PKG_PRKG1_ST	Q8WZ42	TTN	Q13976	PRKG1	S31449	R31445K	31445	Missense	distal	-4	no	7.134	6.830	EPSD	COSMIC	7.092	Loss
AGC_PKG_PRKG1_ST	Q8WZ42	TTN	Q13976	PRKG1	S31449	P31443L	31443	Missense	distal	-6	no	7.134	6.823	EPSD	COSMIC	7.092	Loss
AGC_PKG_PRKG1_ST	Q8WZ42	TTN	Q13976	PRKG1	S31456	L31454I	31454	Missense	proximal	-2	no	7.451	6.739	EPSD	COSMIC	7.092	Loss
AGC_PKG_PRKG1_ST	Q8WZ42	TTN	Q13976	PRKG1	S31509	M31508T	31508	Missense	proximal	-1	no	7.333	7.341	EPSD	COSMIC	7.092	Up-regulation
AGC_PKG_PRKG1_ST	Q8WZ42	TTN	Q13976	PRKG1	S31509	T31514A	31514	Missense	distal	5	no	7.333	7.323	EPSD	COSMIC	7.092	Down-regulation
AGC_PKG_PRKG1_ST	Q8WZ42	TTN	Q13976	PRKG1	S31510	M31508T	31508	Missense	proximal	-2	no	9.289	8.960	EPSD	COSMIC	7.092	Down-regulation
AGC_PKG_PRKG1_ST	Q8WZ42	TTN	Q13976	PRKG1	S31510	T31514A	31514	Missense	distal	4	no	9.289	9.286	EPSD	COSMIC	7.092	Down-regulation
AGC_PKG_PRKG1_ST	Q8WZ42	TTN	Q13976	PRKG1	T31516	T31514A	31514	Missense	proximal	-2	no	7.639	7.776	EPSD	COSMIC	7.092	Up-regulation
AGC_PKG_PRKG1_ST	Q8WZ42	TTN	Q13976	PRKG1	S31870	R31867M	31867	Missense	distal	-3	no	8.970	3.666	EPSD	COSMIC	7.092	Loss
AGC_PKG_PRKG1_ST	Q8WZ42	TTN	Q13976	PRKG1	S31870	C31876F	31876	Missense	distal	6	no	8.970	8.982	EPSD	COSMIC	7.092	Up-regulation
AGC_PKG_PRKG1_ST	Q8WZ42	TTN	Q13976	PRKG1	S31870	T31873A	31873	Missense	distal	3	no	8.970	9.002	EPSD	COSMIC	7.092	Up-regulation
AGC_PKG_PRKG1_ST	Q8WZ42	TTN	Q13976	PRKG1	T32010	V32005A	32005	Missense	distal	-5	no	8.071	7.947	EPSD	COSMIC	7.092	Down-regulation
AGC_PKG_PRKG1_ST	Q8WZ42	TTN	Q13976	PRKG1	T32010	R32007H	32007	Missense	distal	-3	no	8.071	2.004	EPSD	COSMIC	7.092	Loss
AGC_PKG_PRKG1_ST	Q8WZ42	TTN	Q13976	PRKG1	T32010	R32007C	32007	Missense	distal	-3	no	8.071	1.049	EPSD	COSMIC	7.092	Loss
AGC_PKG_PRKG1_ST	Q8WZ42	TTN	Q13976	PRKG1	S32064	D32059N	32059	Missense	distal	-5	no	7.111	7.029	EPSD	COSMIC	7.092	Loss
AGC_PKG_PRKG1_ST	Q8WZ42	TTN	Q13976	PRKG1	S32064	R32062Q	32062	Missense	proximal	-2	no	7.111	4.147	EPSD	COSMIC	7.092	Loss
AGC_PKG_PRKG1_ST	Q8WZ42	TTN	Q13976	PRKG1	T32104	R32105H	32105	Missense	proximal	1	no	8.183	7.847	EPSD	COSMIC	7.092	Down-regulation
AGC_PKG_PRKG1_ST	Q8WZ42	TTN	Q13976	PRKG1	T32104	R32097C	32097	Missense	distal	-7	no	8.183	6.755	EPSD	COSMIC	7.092	Loss
AGC_PKG_PRKG1_ST	Q8WZ42	TTN	Q13976	PRKG1	T32104	R32105C	32105	Missense	proximal	1	no	8.183	7.735	EPSD	COSMIC	7.092	Down-regulation
AGC_PKG_PRKG1_ST	Q8WZ42	TTN	Q13976	PRKG1	T32104	V32108M	32108	Missense	distal	4	no	8.183	8.065	EPSD	COSMIC	7.092	Down-regulation
AGC_PKG_PRKG1_ST	Q8WZ42	TTN	Q13976	PRKG1	S32162	E32157Q	32157	Missense	distal	-5	no	7.891	7.738	EPSD	COSMIC	7.092	Down-regulation
AGC_PKG_PRKG1_ST	Q8WZ42	TTN	Q13976	PRKG1	S32311	T32308I	32308	Missense	distal	-3	no	8.049	4.708	EPSD	COSMIC	7.092	Loss
AGC_PKG_PRKG1_ST	Q8WZ42	TTN	Q13976	PRKG1	S32312	T32308I	32308	Missense	distal	-4	no	13.055	12.334	EPSD	COSMIC	7.092	Down-regulation
AGC_PKG_PRKG1_ST	Q8WZ42	TTN	Q13976	PRKG1	T32313	T32308I	32308	Missense	distal	-5	no	9.845	10.063	EPSD	COSMIC	7.092	Up-regulation
AGC_PKG_PRKG1_ST	Q8WZ42	TTN	Q13976	PRKG1	S32424	E32425K	32425	Missense	proximal	1	no	8.046	8.352	EPSD	COSMIC	7.092	Up-regulation
AGC_PKG_PRKG1_ST	Q8WZ42	TTN	Q13976	PRKG1	S32424	E32425G	32425	Missense	proximal	1	no	8.046	8.117	EPSD	COSMIC;CCLE	7.092	Up-regulation
AGC_PKG_PRKG1_ST	Q8WZ42	TTN	Q13976	PRKG1	S32424	Q32428R	32428	Missense	distal	4	no	8.046	7.986	EPSD	COSMIC	7.092	Down-regulation
AGC_PKG_PRKG1_ST	Q8WZ42	TTN	Q13976	PRKG1	S32491	P32496Q	32496	Missense	distal	5	no	7.500	7.571	EPSD	COSMIC	7.092	Up-regulation
AGC_PKG_PRKG1_ST	Q8WZ42	TTN	Q13976	PRKG1	T32607	M32600V	32600	Missense	distal	-7	no	7.297	6.692	EPSD	COSMIC	7.092	Loss
AGC_PKG_PRKG1_ST	Q8WZ42	TTN	Q13976	PRKG1	T32607	K32601N	32601	Missense	distal	-6	no	7.297	6.884	EPSD	COSMIC	7.092	Loss
AGC_PKG_PRKG1_ST	Q8WZ42	TTN	Q13976	PRKG1	T32607	R32606H	32606	Missense	proximal	-1	no	7.297	7.149	EPSD	COSMIC	7.092	Down-regulation
AGC_PKG_PRKG1_ST	Q8WZ42	TTN	Q13976	PRKG1	T32609	R32606H	32606	Missense	distal	-3	no	9.044	2.976	EPSD	COSMIC	7.092	Loss
AGC_PKG_PRKG1_ST	Q8WZ42	TTN	Q13976	PRKG1	S32702	E32700K	32700	Missense	proximal	-2	no	4.110	7.633	EPSD	COSMIC	7.092	Gain
AGC_PKG_PRKG1_ST	Q8WZ42	TTN	Q13976	PRKG1	T32998	V32991A	32991	Missense	distal	-7	no	11.722	12.425	EPSD	COSMIC	7.092	Up-regulation
AGC_PKG_PRKG1_ST	Q8WZ42	TTN	Q13976	PRKG1	T32998	P32999H	32999	Missense	proximal	1	no	11.722	11.823	EPSD	COSMIC;CCLE	7.092	Up-regulation
AGC_PKG_PRKG1_ST	Q8WZ42	TTN	Q13976	PRKG1	S33000	P32999H	32999	Missense	proximal	-1	no	10.239	10.296	EPSD	COSMIC;CCLE	7.092	Up-regulation
AGC_PKG_PRKG1_ST	Q8WZ42	TTN	Q13976	PRKG1	S33013	E33020K	33020	Missense	distal	7	no	12.058	12.142	EPSD	COSMIC	7.092	Up-regulation
AGC_PKG_PRKG1_ST	Q8WZ42	TTN	Q13976	PRKG1	S33088	R33086K	33086	Missense	proximal	-2	no	7.973	6.495	EPSD	COSMIC	7.092	Loss
AGC_PKG_PRKG1_ST	Q8WZ42	TTN	Q13976	PRKG1	S33088	T33094M	33094	Missense	distal	6	no	7.973	7.986	EPSD	COSMIC	7.092	Up-regulation
AGC_PKG_PRKG1_ST	Q8WZ42	TTN	Q13976	PRKG1	S33088	Y33090D	33090	Missense	proximal	2	no	7.973	7.978	EPSD	COSMIC	7.092	Up-regulation
AGC_PKG_PRKG1_ST	Q8WZ42	TTN	Q13976	PRKG1	T33089	R33086K	33086	Missense	distal	-3	no	8.762	6.404	EPSD	COSMIC	7.092	Loss
AGC_PKG_PRKG1_ST	Q8WZ42	TTN	Q13976	PRKG1	T33089	T33094M	33094	Missense	distal	5	no	8.762	8.761	EPSD	COSMIC	7.092	Down-regulation
AGC_PKG_PRKG1_ST	Q8WZ42	TTN	Q13976	PRKG1	T33089	Y33090D	33090	Missense	proximal	1	no	8.762	8.729	EPSD	COSMIC	7.092	Down-regulation
AGC_PKG_PRKG1_ST	Q8WZ42	TTN	Q13976	PRKG1	T33169	E33167Q	33167	Missense	proximal	-2	no	5.898	7.933	EPSD	COSMIC	7.092	Gain
AGC_PKG_PRKG1_ST	Q8WZ42	TTN	Q13976	PRKG1	S33201	R33199Q	33199	Missense	proximal	-2	no	14.703	11.738	EPSD	COSMIC	7.092	Down-regulation
AGC_PKG_PRKG1_ST	Q8WZ42	TTN	Q13976	PRKG1	S33201	R33199W	33199	Missense	proximal	-2	no	14.703	9.373	EPSD	COSMIC	7.092	Down-regulation
AGC_PKG_PRKG1_ST	Q8WZ42	TTN	Q13976	PRKG1	S33203	R33199Q	33199	Missense	distal	-4	no	9.978	9.582	EPSD	COSMIC	7.092	Down-regulation
AGC_PKG_PRKG1_ST	Q8WZ42	TTN	Q13976	PRKG1	S33203	R33199W	33199	Missense	distal	-4	no	9.978	8.806	EPSD	COSMIC	7.092	Down-regulation
AGC_PKG_PRKG1_ST	Q8WZ42	TTN	Q13976	PRKG1	S33235	R33242C	33242	Missense	distal	7	no	7.154	7.042	EPSD	COSMIC	7.092	Loss
AGC_PKG_PRKG1_ST	Q8WZ42	TTN	Q13976	PRKG1	S33235	E33239K	33239	Missense	distal	4	no	7.154	7.039	EPSD	COSMIC	7.092	Loss
AGC_PKG_PRKG1_ST	Q8WZ42	TTN	Q13976	PRKG1	S33235	D33229N	33229	Missense	distal	-6	no	7.154	7.365	EPSD	COSMIC	7.092	Up-regulation
AGC_PKG_PRKG1_ST	Q8WZ42	TTN	Q13976	PRKG1	S33235	D33229A	33229	Missense	distal	-6	no	7.154	7.602	EPSD	COSMIC	7.092	Up-regulation
AGC_PKG_PRKG1_ST	Q8WZ42	TTN	Q13976	PRKG1	T33237	R33242C	33242	Missense	distal	5	no	7.701	7.631	EPSD	COSMIC	7.092	Down-regulation
AGC_PKG_PRKG1_ST	Q8WZ42	TTN	Q13976	PRKG1	T33237	E33239K	33239	Missense	proximal	2	no	7.701	7.752	EPSD	COSMIC	7.092	Up-regulation
AGC_PKG_PRKG1_ST	Q8WZ42	TTN	Q13976	PRKG1	S33245	S33250Y	33250	Missense	distal	5	no	8.318	8.260	EPSD	COSMIC	7.092	Down-regulation
AGC_PKG_PRKG1_ST	Q8WZ42	TTN	Q13976	PRKG1	S33245	R33242C	33242	Missense	distal	-3	no	8.318	1.296	EPSD	COSMIC	7.092	Loss
AGC_PKG_PRKG1_ST	Q8WZ42	TTN	Q13976	PRKG1	S33245	S33245F	33245	Missense	central	0	yes	8.318	0.000	EPSD	COSMIC	7.092	Loss
AGC_PKG_PRKG1_ST	Q8WZ42	TTN	Q13976	PRKG1	S33245	P33248T	33248	Missense	distal	3	no	8.318	8.061	EPSD	COSMIC	7.092	Down-regulation
AGC_PKG_PRKG1_ST	Q8WZ42	TTN	Q13976	PRKG1	S33245	S33245P	33245	Missense	central	0	yes	8.318	0.000	EPSD	COSMIC	7.092	Loss
AGC_PKG_PRKG1_ST	Q8WZ42	TTN	Q13976	PRKG1	S33245	E33239K	33239	Missense	distal	-6	no	8.318	8.799	EPSD	COSMIC	7.092	Up-regulation
AGC_PKG_PRKG1_ST	Q8WZ42	TTN	Q13976	PRKG1	S33245	S33247G	33247	Missense	proximal	2	no	8.318	8.248	EPSD	COSMIC	7.092	Down-regulation
AGC_PKG_PRKG1_ST	Q8WZ42	TTN	Q13976	PRKG1	S33247	S33250Y	33250	Missense	distal	3	no	11.582	11.773	EPSD	COSMIC	7.092	Up-regulation
AGC_PKG_PRKG1_ST	Q8WZ42	TTN	Q13976	PRKG1	S33247	R33242C	33242	Missense	distal	-5	no	11.582	11.839	EPSD	COSMIC	7.092	Up-regulation
AGC_PKG_PRKG1_ST	Q8WZ42	TTN	Q13976	PRKG1	S33247	S33245F	33245	Missense	proximal	-2	no	11.582	10.820	EPSD	COSMIC	7.092	Down-regulation
AGC_PKG_PRKG1_ST	Q8WZ42	TTN	Q13976	PRKG1	S33247	P33248T	33248	Missense	proximal	1	no	11.582	11.793	EPSD	COSMIC	7.092	Up-regulation
AGC_PKG_PRKG1_ST	Q8WZ42	TTN	Q13976	PRKG1	S33247	S33245P	33245	Missense	proximal	-2	no	11.582	11.231	EPSD	COSMIC	7.092	Down-regulation
AGC_PKG_PRKG1_ST	Q8WZ42	TTN	Q13976	PRKG1	S33247	S33247G	33247	Missense	central	0	yes	11.582	0.000	EPSD	COSMIC	7.092	Loss
AGC_PKG_PRKG1_ST	Q8WZ42	TTN	Q13976	PRKG1	S33256	S33250Y	33250	Missense	distal	-6	no	8.196	7.833	EPSD	COSMIC	7.092	Down-regulation
AGC_PKG_PRKG1_ST	Q8WZ42	TTN	Q13976	PRKG1	S33430	E33433Q	33433	Missense	distal	3	no	8.517	8.333	EPSD	COSMIC	7.092	Down-regulation
AGC_PKG_PRKG1_ST	Q8WZ42	TTN	Q13976	PRKG1	S33465	E33462Q	33462	Missense	distal	-3	no	4.084	7.191	EPSD	COSMIC	7.092	Gain
AGC_PKG_PRKG1_ST	Q8WZ42	TTN	Q13976	PRKG1	T33478	E33475K	33475	Missense	distal	-3	no	4.112	8.695	EPSD	COSMIC	7.092	Gain
AGC_PKG_PRKG1_ST	Q8WZ42	TTN	Q13976	PRKG1	T33478	E33475Q	33475	Missense	distal	-3	no	4.112	7.219	EPSD	COSMIC;CCLE	7.092	Gain
AGC_PKG_PRKG1_ST	Q8WZ42	TTN	Q13976	PRKG1	S33496	E33501Q	33501	Missense	distal	5	no	9.482	9.539	EPSD	COSMIC	7.092	Up-regulation
AGC_PKG_PRKG1_ST	Q8WZ42	TTN	Q13976	PRKG1	S33496	G33502S	33502	Missense	distal	6	no	9.482	9.339	EPSD	COSMIC	7.092	Down-regulation
AGC_PKG_PRKG1_ST	Q8WZ42	TTN	Q13976	PRKG1	S33496	P33494S	33494	Missense	proximal	-2	no	9.482	9.833	EPSD	COSMIC	7.092	Up-regulation
AGC_PKG_PRKG1_ST	Q8WZ42	TTN	Q13976	PRKG1	T33498	E33501Q	33501	Missense	distal	3	no	7.239	7.055	EPSD	COSMIC	7.092	Loss
AGC_PKG_PRKG1_ST	Q8WZ42	TTN	Q13976	PRKG1	T33498	G33502S	33502	Missense	distal	4	no	7.239	7.128	EPSD	COSMIC	7.092	Down-regulation
AGC_PKG_PRKG1_ST	Q8WZ42	TTN	Q13976	PRKG1	T33498	P33494S	33494	Missense	distal	-4	no	7.239	7.662	EPSD	COSMIC	7.092	Up-regulation
AGC_PKG_PRKG1_ST	Q8WZ42	TTN	Q13976	PRKG1	S33595	R33599W	33599	Missense	distal	4	no	8.417	8.634	EPSD	COSMIC	7.092	Up-regulation
AGC_PKG_PRKG1_ST	Q8WZ42	TTN	Q13976	PRKG1	S33595	R33599Q	33599	Missense	distal	4	no	8.417	8.476	EPSD	COSMIC	7.092	Up-regulation
AGC_PKG_PRKG1_ST	Q8WZ42	TTN	Q13976	PRKG1	S33602	R33599W	33599	Missense	distal	-3	no	10.132	2.460	EPSD	COSMIC	7.092	Loss
AGC_PKG_PRKG1_ST	Q8WZ42	TTN	Q13976	PRKG1	S33602	V33606I	33606	Missense	distal	4	no	10.132	10.194	EPSD	COSMIC	7.092	Up-regulation
AGC_PKG_PRKG1_ST	Q8WZ42	TTN	Q13976	PRKG1	S33602	R33599Q	33599	Missense	distal	-3	no	10.132	6.298	EPSD	COSMIC	7.092	Loss
AGC_PKG_PRKG1_ST	Q8WZ42	TTN	Q13976	PRKG1	S33614	K33613Q	33613	Missense	proximal	-1	no	10.333	10.327	EPSD	COSMIC	7.092	Down-regulation
AGC_PKG_PRKG1_ST	Q8WZ42	TTN	Q13976	PRKG1	S33614	P33620S	33620	Missense	distal	6	no	10.333	10.097	EPSD	COSMIC	7.092	Down-regulation
AGC_PKG_PRKG1_ST	Q8WZ42	TTN	Q13976	PRKG1	S33624	P33620S	33620	Missense	distal	-4	no	7.698	8.121	EPSD	COSMIC	7.092	Up-regulation
AGC_PKG_PRKG1_ST	Q8WZ42	TTN	Q13976	PRKG1	S33885	Q33882H	33882	Missense	distal	-3	no	8.568	6.335	EPSD	COSMIC	7.092	Loss
AGC_PKG_PRKG1_ST	Q8WZ42	TTN	Q13976	PRKG1	S33956	H33949Y	33949	Missense	distal	-7	no	7.465	7.216	EPSD	COSMIC	7.092	Down-regulation
AGC_PKG_PRKG1_ST	Q8WZ42	TTN	Q13976	PRKG1	S34298	Q34299K	34299	Missense	proximal	1	no	7.575	7.610	EPSD	COSMIC	7.092	Up-regulation
AGC_PKG_PRKG1_ST	Q8WZ42	TTN	Q13976	PRKG1	S34298	G34293E	34293	Missense	distal	-5	no	7.575	7.622	EPSD	COSMIC	7.092	Up-regulation
AGC_PKG_PRKG1_ST	Q05469	LIPE	Q13976	PRKG1	S200	Q198H	198	Missense	proximal	-2	no	7.726	6.433	EPSD	COSMIC	7.092	Loss
AGC_PKG_PRKG1_ST	Q05469	LIPE	Q13976	PRKG1	T813	R818Q	818	Missense	distal	5	no	11.780	11.755	EPSD	COSMIC;GDSC	7.092	Down-regulation
AGC_PKG_PRKG1_ST	Q05469	LIPE	Q13976	PRKG1	T813	L815P	815	Missense	proximal	2	no	11.780	11.824	EPSD	COSMIC	7.092	Up-regulation
AGC_PKG_PRKG1_ST	Q05469	LIPE	Q13976	PRKG1	S950	G953C	953	Missense	distal	3	no	7.217	7.213	EPSD	COSMIC	7.092	Down-regulation
AGC_PKG_PRKG1_ST	Q05469	LIPE	Q13976	PRKG1	S951	G953C	953	Missense	proximal	2	no	13.709	13.700	EPSD	COSMIC	7.092	Down-regulation
AGC_PKG_PRKG1_ST	P41220	RGS2	Q13976	PRKG1	S46	F48L	48	Missense	proximal	2	no	9.681	9.615	PhosphoSitePlus;EPSD	COSMIC	7.092	Down-regulation
AGC_PKG_PRKG1_ST	P41220	RGS2	Q13976	PRKG1	S64	I70M	70	Missense	distal	6	no	8.464	8.185	EPSD;PhosphoSitePlus	COSMIC	7.092	Down-regulation
AGC_PKG_PRKG1_ST	P41220	RGS2	Q13976	PRKG1	S64	G61S	61	Missense	distal	-3	no	8.464	7.565	EPSD;PhosphoSitePlus	COSMIC	7.092	Down-regulation
AGC_PKG_PRKG1_ST	P48995	TRPC1	Q13976	PRKG1	S206	R208Q	208	Missense	proximal	2	no	8.180	8.174	EPSD;PhosphoSitePlus	COSMIC	7.092	Down-regulation
AGC_PKG_PRKG1_ST	P48995	TRPC1	Q13976	PRKG1	S206	A200P	200	Missense	distal	-6	no	8.180	7.909	EPSD;PhosphoSitePlus	COSMIC	7.092	Down-regulation
AGC_PKG_PRKG1_ST	P48995	TRPC1	Q13976	PRKG1	S279	V284A	284	Missense	distal	5	no	8.294	8.344	EPSD	COSMIC	7.092	Up-regulation
AGC_PKG_PRKG1_ST	P48995	TRPC1	Q13976	PRKG1	S308	M305K	305	Missense	distal	-3	no	4.457	7.403	EPSD	COSMIC	7.092	Gain
AGC_PKG_PRKG1_ST	P48995	TRPC1	Q13976	PRKG1	T347	R344I	344	Missense	distal	-3	no	10.040	1.533	PhosphoSitePlus;EPSD	COSMIC	7.092	Loss
AGC_PKG_PRKG1_ST	P48995	TRPC1	Q13976	PRKG1	T415	G417W	417	Missense	proximal	2	no	7.467	7.425	EPSD	COSMIC;CCLE	7.092	Down-regulation
AGC_PKG_PRKG1_ST	P48995	TRPC1	Q13976	PRKG1	S752	Q748E	748	Missense	distal	-4	no	9.284	8.715	EPSD	COSMIC	7.092	Down-regulation
AGC_PKG_PRKG1_ST	P48995	TRPC1	Q13976	PRKG1	S752	Q755K	755	Missense	distal	3	no	9.284	9.294	EPSD	COSMIC	7.092	Up-regulation
AGC_PKG_PRKG1_ST	P31645	SLC6A4	Q13976	PRKG1	S13	L12Q	12	Missense	proximal	-1	no	8.019	8.257	EPSD	COSMIC	7.092	Up-regulation
AGC_PKG_PRKG1_ST	P31645	SLC6A4	Q13976	PRKG1	S13	C15S	15	Missense	proximal	2	no	8.019	8.099	EPSD	COSMIC	7.092	Up-regulation
AGC_PKG_PRKG1_ST	P31645	SLC6A4	Q13976	PRKG1	S44	Y47C	47	Missense	distal	3	no	7.975	7.941	EPSD	COSMIC	7.092	Down-regulation
AGC_PKG_PRKG1_ST	P31645	SLC6A4	Q13976	PRKG1	S62	G56E	56	Missense	distal	-6	no	8.971	8.841	EPSD	COSMIC	7.092	Down-regulation
AGC_PKG_PRKG1_ST	Q13976	PRKG1	Q13976	PRKG1	S27	K20E	20	Missense	distal	-7	no	10.846	9.845	EPSD	COSMIC	7.092	Down-regulation
AGC_PKG_PRKG1_ST	Q13976	PRKG1	Q13976	PRKG1	T59	G63D	63	Missense	distal	4	no	8.128	8.151	EPSD	COSMIC	7.092	Up-regulation
AGC_PKG_PRKG1_ST	Q13976	PRKG1	Q13976	PRKG1	S65	G63D	63	Missense	proximal	-2	no	8.252	5.837	PhosphoSitePlus	COSMIC	7.092	Loss
AGC_PKG_PRKG1_ST	Q13976	PRKG1	Q13976	PRKG1	S273	N267S	267	Missense	distal	-6	no	7.247	7.529	EPSD	COSMIC	7.092	Up-regulation
AGC_PKG_PRKG1_ST	Q13976	PRKG1	Q13976	PRKG1	S273	N267Y	267	Missense	distal	-6	no	7.247	7.165	EPSD	COSMIC	7.092	Down-regulation
AGC_PKG_PRKG1_ST	Q13976	PRKG1	Q13976	PRKG1	S273	E271V	271	Missense	proximal	-2	no	7.247	8.289	EPSD	COSMIC	7.092	Up-regulation
AGC_PKG_PRKG1_ST	Q13976	PRKG1	Q13976	PRKG1	S273	D277Y	277	Missense	distal	4	no	7.247	7.263	EPSD	COSMIC	7.092	Up-regulation
AGC_PKG_PRKG1_ST	Q13976	PRKG1	Q13976	PRKG1	S273	P278Q	278	Missense	distal	5	no	7.247	7.318	EPSD	COSMIC	7.092	Up-regulation
AGC_PKG_PRKG1_ST	Q13976	PRKG1	Q13976	PRKG1	S273	V279F	279	Missense	distal	6	no	7.247	7.211	EPSD	COSMIC	7.092	Down-regulation
AGC_PKG_PRKG1_ST	Q13976	PRKG1	Q13976	PRKG1	S273	E276K	276	Missense	distal	3	no	7.247	7.074	EPSD	COSMIC;CCLE	7.092	Loss
AGC_PKG_PRKG1_ST	Q13976	PRKG1	Q13976	PRKG1	S273	R270H	270	Missense	distal	-3	no	7.247	1.180	EPSD	COSMIC	7.092	Loss
AGC_PKG_PRKG1_ST	Q13976	PRKG1	Q13976	PRKG1	S273	P274L	274	Missense	proximal	1	no	7.247	7.017	EPSD	COSMIC;CCLE	7.092	Loss
AGC_PKG_PRKG1_ST	Q13976	PRKG1	Q13976	PRKG1	S273	P278T	278	Missense	distal	5	no	7.247	7.314	EPSD	COSMIC	7.092	Up-regulation
AGC_PKG_PRKG1_ST	Q13976	PRKG1	Q13976	PRKG1	S273	R270S	270	Missense	distal	-3	no	7.247	1.759	EPSD	COSMIC	7.092	Loss
AGC_PKG_PRKG1_ST	Q13976	PRKG1	Q13976	PRKG1	S273	V268I	268	Missense	distal	-5	no	7.247	7.350	EPSD	COSMIC	7.092	Up-regulation
AGC_PKG_PRKG1_ST	Q13976	PRKG1	Q13976	PRKG1	T515	G512R	512	Missense	distal	-3	no	4.463	9.053	EPSD	COSMIC	7.092	Gain
AGC_PKG_PRKG1_ST	Q03393	PTS	Q13976	PRKG1	S19	V14A	14	Missense	distal	-5	no	14.044	13.920	PhosphoSitePlus	COSMIC	7.092	Down-regulation
AGC_PKG_PRKG1_ST	Q03393	PTS	Q13976	PRKG1	S32	L37F	37	Missense	distal	5	no	7.026	7.095	EPSD	COSMIC	7.092	Gain
AGC_PKG_PRKG1_ST	Q15052	ARHGEF6	Q13976	PRKG1	S101	L103P	103	Missense	proximal	2	no	7.089	7.133	EPSD	COSMIC	7.092	Gain
AGC_PKG_PRKG1_ST	Q15052	ARHGEF6	Q13976	PRKG1	S101	N95S	95	Missense	distal	-6	no	7.089	7.370	EPSD	COSMIC	7.092	Gain
AGC_PKG_PRKG1_ST	Q15052	ARHGEF6	Q13976	PRKG1	S150	Q149E	149	Missense	proximal	-1	no	9.345	9.189	EPSD	COSMIC	7.092	Down-regulation
AGC_PKG_PRKG1_ST	Q15052	ARHGEF6	Q13976	PRKG1	S150	Q147H	147	Missense	distal	-3	no	9.345	7.112	EPSD	COSMIC	7.092	Down-regulation
AGC_PKG_PRKG1_ST	Q15052	ARHGEF6	Q13976	PRKG1	S225	P226S	226	Missense	proximal	1	no	10.936	11.197	EPSD	COSMIC	7.092	Up-regulation
AGC_PKG_PRKG1_ST	Q15052	ARHGEF6	Q13976	PRKG1	S225	S219C	219	Missense	distal	-6	no	10.936	10.564	EPSD	COSMIC	7.092	Down-regulation
AGC_PKG_PRKG1_ST	Q15052	ARHGEF6	Q13976	PRKG1	S225	V229D	229	Missense	distal	4	no	10.936	10.910	EPSD	COSMIC	7.092	Down-regulation
AGC_PKG_PRKG1_ST	Q15052	ARHGEF6	Q13976	PRKG1	S225	S220R	220	Missense	distal	-5	no	10.936	10.795	EPSD	COSMIC	7.092	Down-regulation
AGC_PKG_PRKG1_ST	Q15052	ARHGEF6	Q13976	PRKG1	S488	M487R	487	Missense	proximal	-1	no	8.074	8.186	EPSD	COSMIC;GDSC;CCLE	7.092	Up-regulation
AGC_PKG_PRKG1_ST	Q15052	ARHGEF6	Q13976	PRKG1	S488	A483E	483	Missense	distal	-5	no	8.074	8.208	EPSD	COSMIC	7.092	Up-regulation
AGC_PKG_PRKG1_ST	Q15052	ARHGEF6	Q13976	PRKG1	S488	P485H	485	Missense	distal	-3	no	8.074	6.908	EPSD	COSMIC	7.092	Loss
AGC_PKG_PRKG1_ST	Q15052	ARHGEF6	Q13976	PRKG1	S488	S488R	488	Missense	central	0	yes	8.074	0.000	EPSD	COSMIC	7.092	Loss
AGC_PKG_PRKG1_ST	Q15052	ARHGEF6	Q13976	PRKG1	S488	R486L	486	Missense	proximal	-2	no	8.074	2.780	EPSD	COSMIC	7.092	Loss
AGC_PKG_PRKG1_ST	Q15052	ARHGEF6	Q13976	PRKG1	S552	S554T	554	Missense	proximal	2	no	8.090	8.059	EPSD	COSMIC	7.092	Down-regulation
AGC_PKG_PRKG1_ST	Q15052	ARHGEF6	Q13976	PRKG1	S552	R548G	548	Missense	distal	-4	no	8.090	7.407	EPSD	COSMIC	7.092	Down-regulation
AGC_PKG_PRKG1_ST	Q15052	ARHGEF6	Q13976	PRKG1	S552	A551T	551	Missense	proximal	-1	no	8.090	8.095	EPSD	COSMIC	7.092	Up-regulation
AGC_PKG_PRKG1_ST	Q15052	ARHGEF6	Q13976	PRKG1	S561	S554T	554	Missense	distal	-7	no	9.873	9.660	EPSD	COSMIC	7.092	Down-regulation
AGC_PKG_PRKG1_ST	Q15052	ARHGEF6	Q13976	PRKG1	S561	S561L	561	Missense	central	0	yes	9.873	0.000	EPSD	COSMIC	7.092	Loss
AGC_PKG_PRKG1_ST	Q15052	ARHGEF6	Q13976	PRKG1	S561	A566T	566	Missense	distal	5	no	9.873	9.883	EPSD	COSMIC	7.092	Up-regulation
AGC_PKG_PRKG1_ST	Q15052	ARHGEF6	Q13976	PRKG1	S561	A566S	566	Missense	distal	5	no	9.873	9.888	EPSD	COSMIC	7.092	Up-regulation
AGC_PKG_PRKG1_ST	Q15052	ARHGEF6	Q13976	PRKG1	S568	S572F	572	Missense	distal	4	no	7.094	7.223	EPSD	COSMIC	7.092	Up-regulation
AGC_PKG_PRKG1_ST	Q15052	ARHGEF6	Q13976	PRKG1	S568	G574R	574	Missense	distal	6	no	7.094	6.879	EPSD	COSMIC	7.092	Loss
AGC_PKG_PRKG1_ST	Q15052	ARHGEF6	Q13976	PRKG1	S568	S561L	561	Missense	distal	-7	no	7.094	5.711	EPSD	COSMIC	7.092	Loss
AGC_PKG_PRKG1_ST	Q15052	ARHGEF6	Q13976	PRKG1	S568	T573I	573	Missense	distal	5	no	7.094	6.999	EPSD	COSMIC	7.092	Loss
AGC_PKG_PRKG1_ST	Q15052	ARHGEF6	Q13976	PRKG1	S568	A566T	566	Missense	proximal	-2	no	7.094	6.958	EPSD	COSMIC	7.092	Loss
AGC_PKG_PRKG1_ST	Q15052	ARHGEF6	Q13976	PRKG1	S568	A566S	566	Missense	proximal	-2	no	7.094	7.142	EPSD	COSMIC	7.092	Up-regulation
AGC_PKG_PRKG1_ST	Q15052	ARHGEF6	Q13976	PRKG1	T635	R637K	637	Missense	proximal	2	no	9.550	9.535	EPSD	COSMIC	7.092	Down-regulation
AGC_PKG_PRKG1_ST	Q15052	ARHGEF6	Q13976	PRKG1	S640	R647W	647	Missense	distal	7	no	12.918	12.763	EPSD	COSMIC	7.092	Down-regulation
AGC_PKG_PRKG1_ST	Q15052	ARHGEF6	Q13976	PRKG1	S640	R637K	637	Missense	distal	-3	no	12.918	10.560	EPSD	COSMIC	7.092	Down-regulation
AGC_PKG_PRKG1_ST	Q15052	ARHGEF6	Q13976	PRKG1	T650	R647W	647	Missense	distal	-3	no	7.923	0.251	EPSD	COSMIC	7.092	Loss
AGC_PKG_PRKG1_ST	Q15052	ARHGEF6	Q13976	PRKG1	T650	E654K	654	Missense	distal	4	no	7.923	7.808	EPSD	COSMIC;GDSC;CCLE	7.092	Down-regulation
AGC_PKG_PRKG1_ST	Q15052	ARHGEF6	Q13976	PRKG1	S679	G677R	677	Missense	proximal	-2	no	4.596	8.083	EPSD	COSMIC	7.092	Gain
AGC_PKG_PRKG1_ST	Q15052	ARHGEF6	Q13976	PRKG1	T680	G677R	677	Missense	distal	-3	no	4.338	8.928	EPSD	COSMIC	7.092	Gain
AGC_PKG_PRKG1_ST	Q15052	ARHGEF6	Q13976	PRKG1	S684	P691S	691	Missense	distal	7	no	11.623	11.725	PhosphoSitePlus	COSMIC;GDSC;CCLE	7.092	Up-regulation
AGC_PKG_PRKG1_ST	Q15052	ARHGEF6	Q13976	PRKG1	S684	S684C	684	Missense	central	0	yes	11.623	0.000	PhosphoSitePlus	COSMIC	7.092	Loss
AGC_PKG_PRKG1_ST	Q15052	ARHGEF6	Q13976	PRKG1	S684	G677R	677	Missense	distal	-7	no	11.623	12.772	PhosphoSitePlus	COSMIC	7.092	Up-regulation
AGC_PKG_PRKG1_ST	Q15052	ARHGEF6	Q13976	PRKG1	S684	D683V	683	Missense	proximal	-1	no	11.623	11.670	PhosphoSitePlus	COSMIC	7.092	Up-regulation
AGC_PKG_PRKG1_ST	Q15052	ARHGEF6	Q13976	PRKG1	S684	L690I	690	Missense	distal	6	no	11.623	11.591	PhosphoSitePlus	COSMIC	7.092	Down-regulation
AGC_PKG_PRKG1_ST	Q76M96	CCDC80	Q13976	PRKG1	S79	R77M	77	Missense	proximal	-2	no	15.103	11.839	EPSD	COSMIC	7.092	Down-regulation
AGC_PKG_PRKG1_ST	Q76M96	CCDC80	Q13976	PRKG1	S79	S79I	79	Missense	central	0	yes	15.103	0.000	EPSD	COSMIC	7.092	Loss
AGC_PKG_PRKG1_ST	Q76M96	CCDC80	Q13976	PRKG1	S134	P139S	139	Missense	distal	5	no	10.300	10.372	EPSD	COSMIC	7.092	Up-regulation
AGC_PKG_PRKG1_ST	Q76M96	CCDC80	Q13976	PRKG1	S134	N140S	140	Missense	distal	6	no	10.300	10.157	EPSD	COSMIC	7.092	Down-regulation
AGC_PKG_PRKG1_ST	Q76M96	CCDC80	Q13976	PRKG1	T351	S346L	346	Missense	distal	-5	no	6.880	7.117	EPSD	COSMIC	7.092	Gain
AGC_PKG_PRKG1_ST	Q76M96	CCDC80	Q13976	PRKG1	T352	A358S	358	Missense	distal	6	no	7.459	7.427	EPSD	COSMIC	7.092	Down-regulation
AGC_PKG_PRKG1_ST	Q76M96	CCDC80	Q13976	PRKG1	T352	S346L	346	Missense	distal	-6	no	7.459	6.832	EPSD	COSMIC	7.092	Loss
AGC_PKG_PRKG1_ST	Q76M96	CCDC80	Q13976	PRKG1	S366	R367W	367	Missense	proximal	1	no	10.079	9.508	EPSD	COSMIC	7.092	Down-regulation
AGC_PKG_PRKG1_ST	Q76M96	CCDC80	Q13976	PRKG1	S366	A372D	372	Missense	distal	6	no	10.079	10.279	EPSD	COSMIC	7.092	Up-regulation
AGC_PKG_PRKG1_ST	Q76M96	CCDC80	Q13976	PRKG1	S366	R367Q	367	Missense	proximal	1	no	10.079	9.915	EPSD	COSMIC;GDSC	7.092	Down-regulation
AGC_PKG_PRKG1_ST	Q76M96	CCDC80	Q13976	PRKG1	T370	R367W	367	Missense	distal	-3	no	9.765	2.092	EPSD	COSMIC	7.092	Loss
AGC_PKG_PRKG1_ST	Q76M96	CCDC80	Q13976	PRKG1	T370	A372D	372	Missense	proximal	2	no	9.765	9.703	EPSD	COSMIC	7.092	Down-regulation
AGC_PKG_PRKG1_ST	Q76M96	CCDC80	Q13976	PRKG1	T370	R367Q	367	Missense	distal	-3	no	9.765	5.930	EPSD	COSMIC;GDSC	7.092	Loss
AGC_PKG_PRKG1_ST	Q76M96	CCDC80	Q13976	PRKG1	T377	A372D	372	Missense	distal	-5	no	7.007	7.183	EPSD	COSMIC	7.092	Gain
AGC_PKG_PRKG1_ST	Q76M96	CCDC80	Q13976	PRKG1	S409	R406W	406	Missense	distal	-3	no	12.972	5.299	EPSD;PhosphoSitePlus	COSMIC	7.092	Loss
AGC_PKG_PRKG1_ST	Q76M96	CCDC80	Q13976	PRKG1	S409	L414F	414	Missense	distal	5	no	12.972	13.041	EPSD;PhosphoSitePlus	COSMIC	7.092	Up-regulation
AGC_PKG_PRKG1_ST	Q76M96	CCDC80	Q13976	PRKG1	S434	R431K	431	Missense	distal	-3	no	13.432	11.074	PhosphoSitePlus;EPSD	COSMIC	7.092	Down-regulation
AGC_PKG_PRKG1_ST	Q76M96	CCDC80	Q13976	PRKG1	S434	T430I	430	Missense	distal	-4	no	13.432	12.711	PhosphoSitePlus;EPSD	COSMIC	7.092	Down-regulation
AGC_PKG_PRKG1_ST	Q76M96	CCDC80	Q13976	PRKG1	S434	A436T	436	Missense	proximal	2	no	13.432	13.425	PhosphoSitePlus;EPSD	COSMIC	7.092	Down-regulation
AGC_PKG_PRKG1_ST	Q76M96	CCDC80	Q13976	PRKG1	S611	T605M	605	Missense	distal	-6	no	7.178	7.147	EPSD	COSMIC	7.092	Down-regulation
AGC_PKG_PRKG1_ST	Q76M96	CCDC80	Q13976	PRKG1	S611	P608S	608	Missense	distal	-3	no	7.178	6.591	EPSD	COSMIC	7.092	Loss
AGC_PKG_PRKG1_ST	Q76M96	CCDC80	Q13976	PRKG1	S611	S618Y	618	Missense	distal	7	no	7.178	7.094	EPSD	COSMIC	7.092	Down-regulation
AGC_PKG_PRKG1_ST	O76074	PDE5A	Q13976	PRKG1	S102	G95E	95	Missense	distal	-7	no	11.786	11.468	PhosphoSitePlus	COSMIC	7.092	Down-regulation
AGC_PKG_PRKG1_ST	O76074	PDE5A	Q13976	PRKG1	S102	A103T	103	Missense	proximal	1	no	11.786	11.748	PhosphoSitePlus	COSMIC	7.092	Down-regulation
AGC_PKG_PRKG1_ST	O76074	PDE5A	Q13976	PRKG1	S102	S102P	102	Missense	central	0	yes	11.786	0.000	PhosphoSitePlus	COSMIC	7.092	Loss
AGC_PKG_PRKG1_ST	O76074	PDE5A	Q13976	PRKG1	S102	T96K	96	Missense	distal	-6	no	11.786	12.001	PhosphoSitePlus	COSMIC	7.092	Up-regulation
AGC_PKG_PRKG1_ST	O76074	PDE5A	Q13976	PRKG1	S102	P109R	109	Missense	distal	7	no	11.786	11.926	PhosphoSitePlus	COSMIC	7.092	Up-regulation
AGC_PKG_PRKG1_ST	O76074	PDE5A	Q13976	PRKG1	S102	R99K	99	Missense	distal	-3	no	11.786	9.428	PhosphoSitePlus	COSMIC	7.092	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P19634	SLC9A1	P28482	MAPK1	S11	R4W	4	Missense	distal	-7	no	13.032	12.981	EPSD	COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P19634	SLC9A1	P28482	MAPK1	T68	T68I	68	Missense	central	0	yes	13.700	0.000	EPSD	COSMIC	8.102	Loss
CMGC_MAPK_ERK1_MAPK1_ST	P19634	SLC9A1	P28482	MAPK1	T68	V67I	67	Missense	proximal	-1	no	13.700	13.660	EPSD	COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P19634	SLC9A1	P28482	MAPK1	S599	V604I	604	Missense	distal	5	no	8.293	8.119	EPSD	COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P19634	SLC9A1	P28482	MAPK1	S599	V601I	601	Missense	proximal	2	no	8.293	8.176	EPSD	COSMIC;GDSC;CCLE	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P19634	SLC9A1	P28482	MAPK1	S616	A622S	622	Missense	distal	6	no	7.996	8.293	EPSD	COSMIC	8.102	Gain
CMGC_MAPK_ERK1_MAPK1_ST	P19634	SLC9A1	P28482	MAPK1	S616	P611L	611	Missense	distal	-5	no	7.996	8.145	EPSD	COSMIC	8.102	Gain
CMGC_MAPK_ERK1_MAPK1_ST	P19634	SLC9A1	P28482	MAPK1	S693	R700H	700	Missense	distal	7	no	14.394	14.613	EPSD;PhosphoSitePlus	COSMIC;GDSC;CCLE	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P19634	SLC9A1	P28482	MAPK1	S723	P724Q	724	Missense	proximal	1	no	17.354	8.860	EPSD;PhosphoSitePlus	COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P19634	SLC9A1	P28482	MAPK1	S723	I717V	717	Missense	distal	-6	no	17.354	17.395	EPSD;PhosphoSitePlus	COSMIC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P19634	SLC9A1	P28482	MAPK1	S726	P724Q	724	Missense	proximal	-2	no	16.735	13.742	EPSD;PhosphoSitePlus	COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P19634	SLC9A1	P28482	MAPK1	S770	P772L	772	Missense	proximal	2	no	8.372	8.224	EPSD;PhosphoSitePlus	COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P19634	SLC9A1	P28482	MAPK1	S770	P772S	772	Missense	proximal	2	no	8.372	8.344	EPSD;PhosphoSitePlus	COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P19634	SLC9A1	P28482	MAPK1	S771	P772L	772	Missense	proximal	1	no	15.111	6.301	EPSD;PhosphoSitePlus	COSMIC	8.102	Loss
CMGC_MAPK_ERK1_MAPK1_ST	P19634	SLC9A1	P28482	MAPK1	S771	P772S	772	Missense	proximal	1	no	15.111	5.716	EPSD;PhosphoSitePlus	COSMIC	8.102	Loss
CMGC_MAPK_ERK1_MAPK1_ST	P19634	SLC9A1	P28482	MAPK1	T779	P780S	780	Missense	proximal	1	no	15.577	6.182	PhosphoSitePlus;EPSD	COSMIC	8.102	Loss
CMGC_MAPK_ERK1_MAPK1_ST	P19634	SLC9A1	P28482	MAPK1	T779	P772L	772	Missense	distal	-7	no	15.577	15.565	PhosphoSitePlus;EPSD	COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P19634	SLC9A1	P28482	MAPK1	T779	P786S	786	Missense	distal	7	no	15.577	15.588	PhosphoSitePlus;EPSD	COSMIC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P19634	SLC9A1	P28482	MAPK1	T779	P772S	772	Missense	distal	-7	no	15.577	15.573	PhosphoSitePlus;EPSD	COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P19634	SLC9A1	P28482	MAPK1	S785	P780S	780	Missense	distal	-5	no	13.035	13.109	EPSD;PhosphoSitePlus	COSMIC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P19634	SLC9A1	P28482	MAPK1	S785	P786S	786	Missense	proximal	1	no	13.035	3.640	EPSD;PhosphoSitePlus	COSMIC	8.102	Loss
CMGC_MAPK_ERK1_MAPK1_ST	P19634	SLC9A1	P28482	MAPK1	S788	P786S	786	Missense	proximal	-2	no	8.359	5.525	EPSD	COSMIC	8.102	Loss
CMGC_MAPK_ERK1_MAPK1_ST	P11388	TOP2A	P28482	MAPK1	S802	M809V	809	Missense	distal	7	no	14.157	14.080	EPSD	COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P11388	TOP2A	P28482	MAPK1	T950	T947I	947	Missense	distal	-3	no	14.257	14.025	EPSD	COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P11388	TOP2A	P28482	MAPK1	T950	T947A	947	Missense	distal	-3	no	14.257	14.100	EPSD	COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P11388	TOP2A	P28482	MAPK1	T950	T950A	950	Missense	central	0	yes	14.257	0.000	EPSD	COSMIC	8.102	Loss
CMGC_MAPK_ERK1_MAPK1_ST	P11388	TOP2A	P28482	MAPK1	S1045	A1046P	1046	Missense	proximal	1	no	5.100	12.730	EPSD	COSMIC	8.102	Gain
CMGC_MAPK_ERK1_MAPK1_ST	P11388	TOP2A	P28482	MAPK1	S1115	K1110E	1110	Missense	distal	-5	no	8.958	8.980	EPSD	COSMIC;GDSC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P11388	TOP2A	P28482	MAPK1	S1213	Q1206H	1206	Missense	distal	-7	no	13.923	13.904	EPSD;PhosphoSitePlus	COSMIC;GDSC;CCLE	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P11388	TOP2A	P28482	MAPK1	S1213	Q1206K	1206	Missense	distal	-7	no	13.923	13.918	EPSD;PhosphoSitePlus	COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P11388	TOP2A	P28482	MAPK1	S1213	P1214S	1214	Missense	proximal	1	no	13.923	4.528	EPSD;PhosphoSitePlus	COSMIC	8.102	Loss
CMGC_MAPK_ERK1_MAPK1_ST	P11388	TOP2A	P28482	MAPK1	S1247	E1242K	1242	Missense	distal	-5	no	14.736	14.714	EPSD;PhosphoSitePlus	COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P11388	TOP2A	P28482	MAPK1	S1393	V1388L	1388	Missense	distal	-5	no	10.974	11.027	EPSD;PhosphoSitePlus	COSMIC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	O00562	PITPNM1	P28482	MAPK1	T287	D289N	289	Missense	proximal	2	no	15.406	15.345	EPSD	COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	O00562	PITPNM1	P28482	MAPK1	T287	P294L	294	Missense	distal	7	no	15.406	15.705	EPSD	COSMIC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	O00562	PITPNM1	P28482	MAPK1	S300	P295S	295	Missense	distal	-5	no	13.181	13.255	EPSD	COSMIC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	O00562	PITPNM1	P28482	MAPK1	S300	P301S	301	Missense	proximal	1	no	13.181	3.786	EPSD	COSMIC	8.102	Loss
CMGC_MAPK_ERK1_MAPK1_ST	O00562	PITPNM1	P28482	MAPK1	S300	P294L	294	Missense	distal	-6	no	13.181	13.089	EPSD	COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	O00562	PITPNM1	P28482	MAPK1	S382	I377V	377	Missense	distal	-5	no	14.761	14.648	EPSD	COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	O00562	PITPNM1	P28482	MAPK1	S382	T389M	389	Missense	distal	7	no	14.761	14.968	EPSD	COSMIC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	O00562	PITPNM1	P28482	MAPK1	T389	G393R	393	Missense	distal	4	no	13.607	13.633	EPSD	COSMIC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	O00562	PITPNM1	P28482	MAPK1	T389	T389M	389	Missense	central	0	yes	13.607	0.000	EPSD	COSMIC	8.102	Loss
CMGC_MAPK_ERK1_MAPK1_ST	O00562	PITPNM1	P28482	MAPK1	S600	P601L	601	Missense	proximal	1	no	16.362	7.553	EPSD	COSMIC	8.102	Loss
CMGC_MAPK_ERK1_MAPK1_ST	O00562	PITPNM1	P28482	MAPK1	S600	R607Q	607	Missense	distal	7	no	16.362	16.478	EPSD	COSMIC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	O00562	PITPNM1	P28482	MAPK1	S621	R619Q	619	Missense	proximal	-2	no	14.648	13.473	EPSD	COSMIC;GDSC;CCLE	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	O00562	PITPNM1	P28482	MAPK1	S638	P633S	633	Missense	distal	-5	no	14.568	14.642	EPSD	COSMIC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	O00562	PITPNM1	P28482	MAPK1	S638	P641L	641	Missense	distal	3	no	14.568	14.657	EPSD	COSMIC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	O00562	PITPNM1	P28482	MAPK1	S638	P633L	633	Missense	distal	-5	no	14.568	14.717	EPSD	COSMIC;GDSC;CCLE	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	O00562	PITPNM1	P28482	MAPK1	S638	G643D	643	Missense	distal	5	no	14.568	14.612	EPSD	COSMIC;GDSC;CCLE	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	O00562	PITPNM1	P28482	MAPK1	T794	A801V	801	Missense	distal	7	no	17.040	17.142	PhosphoSitePlus;EPSD	COSMIC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	O00562	PITPNM1	P28482	MAPK1	T794	T798N	798	Missense	distal	4	no	17.040	17.115	PhosphoSitePlus;EPSD	COSMIC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	O00562	PITPNM1	P28482	MAPK1	T794	V791A	791	Missense	distal	-3	no	17.040	16.980	PhosphoSitePlus;EPSD	COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	O00562	PITPNM1	P28482	MAPK1	T794	L787M	787	Missense	distal	-7	no	17.040	17.031	PhosphoSitePlus;EPSD	COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	O00562	PITPNM1	P28482	MAPK1	T794	S797T	797	Missense	distal	3	no	17.040	17.033	PhosphoSitePlus;EPSD	COSMIC;CCLE	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	O00562	PITPNM1	P28482	MAPK1	S896	E902D	902	Missense	distal	6	no	14.180	14.101	EPSD	COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	O00562	PITPNM1	P28482	MAPK1	S896	E890K	890	Missense	distal	-6	no	14.180	14.155	EPSD	COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	O00562	PITPNM1	P28482	MAPK1	S896	S896I	896	Missense	central	0	yes	14.180	0.000	EPSD	COSMIC	8.102	Loss
CMGC_MAPK_ERK1_MAPK1_ST	O00562	PITPNM1	P28482	MAPK1	S1030	V1035A	1035	Missense	distal	5	no	10.342	10.325	EPSD	COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	O00562	PITPNM1	P28482	MAPK1	T1223	R1218H	1218	Missense	distal	-5	no	17.459	17.537	EPSD;PhosphoSitePlus	COSMIC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	O00562	PITPNM1	P28482	MAPK1	T1223	E1219G	1219	Missense	distal	-4	no	17.459	17.138	EPSD;PhosphoSitePlus	COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P15056	BRAF	P28482	MAPK1	S76	G69S	69	Missense	distal	-7	no	8.648	8.662	EPSD	COSMIC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P15056	BRAF	P28482	MAPK1	S76	P75S	75	Missense	proximal	-1	no	8.648	8.605	EPSD	COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P15056	BRAF	P28482	MAPK1	S76	E80Q	80	Missense	distal	4	no	8.648	8.577	EPSD	COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P15056	BRAF	P28482	MAPK1	S76	P75L	75	Missense	proximal	-1	no	8.648	8.588	EPSD	COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P15056	BRAF	P28482	MAPK1	S76	L79M	79	Missense	distal	3	no	8.648	8.643	EPSD	COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P15056	BRAF	P28482	MAPK1	S151	V157I	157	Missense	distal	6	no	15.658	15.206	EPSD	COSMIC;CCLE	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P15056	BRAF	P28482	MAPK1	S151	S151A	151	Missense	central	0	yes	15.658	0.000	EPSD	COSMIC	8.102	Loss
CMGC_MAPK_ERK1_MAPK1_ST	P15056	BRAF	P28482	MAPK1	S151	P149H	149	Missense	proximal	-2	no	15.658	12.903	EPSD	COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P15056	BRAF	P28482	MAPK1	S317	A322V	322	Missense	distal	5	no	13.415	13.432	EPSD	COSMIC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P15056	BRAF	P28482	MAPK1	S317	T310I	310	Missense	distal	-7	no	13.415	13.400	EPSD	COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P15056	BRAF	P28482	MAPK1	S317	S323L	323	Missense	distal	6	no	13.415	13.008	EPSD	COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P15056	BRAF	P28482	MAPK1	S317	A322T	322	Missense	distal	5	no	13.415	13.501	EPSD	COSMIC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P15056	BRAF	P28482	MAPK1	S317	P321L	321	Missense	distal	4	no	13.415	13.294	EPSD	COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P15056	BRAF	P28482	MAPK1	S317	L312P	312	Missense	distal	-5	no	13.415	13.266	EPSD	COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P15056	BRAF	P28482	MAPK1	S317	G315V	315	Missense	proximal	-2	no	13.415	14.736	EPSD	COSMIC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P15056	BRAF	P28482	MAPK1	S319	A322V	322	Missense	distal	3	no	8.527	8.506	EPSD	COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P15056	BRAF	P28482	MAPK1	S319	S323L	323	Missense	distal	4	no	8.527	8.417	EPSD	COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P15056	BRAF	P28482	MAPK1	S319	A322T	322	Missense	distal	3	no	8.527	8.510	EPSD	COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P15056	BRAF	P28482	MAPK1	S319	I326T	326	Missense	distal	7	no	8.527	8.131	EPSD	COSMIC;GDSC;CCLE	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P15056	BRAF	P28482	MAPK1	S319	P321L	321	Missense	proximal	2	no	8.527	8.379	EPSD	COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P15056	BRAF	P28482	MAPK1	S319	L312P	312	Missense	distal	-7	no	8.527	8.539	EPSD	COSMIC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P15056	BRAF	P28482	MAPK1	S319	G315V	315	Missense	distal	-4	no	8.527	8.523	EPSD	COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P15056	BRAF	P28482	MAPK1	S323	A322V	322	Missense	proximal	-1	no	9.556	9.567	EPSD	COSMIC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P15056	BRAF	P28482	MAPK1	S323	G327W	327	Missense	distal	4	no	9.556	9.300	EPSD	COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P15056	BRAF	P28482	MAPK1	S323	S323L	323	Missense	central	0	yes	9.556	0.000	EPSD	COSMIC	8.102	Loss
CMGC_MAPK_ERK1_MAPK1_ST	P15056	BRAF	P28482	MAPK1	S323	A322T	322	Missense	proximal	-1	no	9.556	9.551	EPSD	COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P15056	BRAF	P28482	MAPK1	S323	I326T	326	Missense	distal	3	no	9.556	9.491	EPSD	COSMIC;GDSC;CCLE	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P15056	BRAF	P28482	MAPK1	S323	P321L	321	Missense	proximal	-2	no	9.556	7.639	EPSD	COSMIC	8.102	Loss
CMGC_MAPK_ERK1_MAPK1_ST	P15056	BRAF	P28482	MAPK1	S333	T332I	332	Missense	proximal	-1	no	15.127	15.103	EPSD	COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P15056	BRAF	P28482	MAPK1	S333	L331F	331	Missense	proximal	-2	no	15.127	14.403	EPSD	COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P15056	BRAF	P28482	MAPK1	S333	P334S	334	Missense	proximal	1	no	15.127	5.732	EPSD	COSMIC	8.102	Loss
CMGC_MAPK_ERK1_MAPK1_ST	P15056	BRAF	P28482	MAPK1	S333	G327W	327	Missense	distal	-6	no	15.127	14.957	EPSD	COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P15056	BRAF	P28482	MAPK1	S333	S339F	339	Missense	distal	6	no	15.127	14.686	EPSD	COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P15056	BRAF	P28482	MAPK1	S333	I326T	326	Missense	distal	-7	no	15.127	15.141	EPSD	COSMIC;GDSC;CCLE	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P15056	BRAF	P28482	MAPK1	S333	S337L	337	Missense	distal	4	no	15.127	15.017	EPSD	COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P15056	BRAF	P28482	MAPK1	S333	S337P	337	Missense	distal	4	no	15.127	15.137	EPSD	COSMIC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P15056	BRAF	P28482	MAPK1	S335	T332I	332	Missense	distal	-3	no	14.911	14.679	EPSD	COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P15056	BRAF	P28482	MAPK1	S335	L331F	331	Missense	distal	-4	no	14.911	14.870	EPSD	COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P15056	BRAF	P28482	MAPK1	S335	P334S	334	Missense	proximal	-1	no	14.911	14.867	EPSD	COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P15056	BRAF	P28482	MAPK1	S335	P341T	341	Missense	distal	6	no	14.911	14.700	EPSD	COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P15056	BRAF	P28482	MAPK1	S335	S339F	339	Missense	distal	4	no	14.911	14.733	EPSD	COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P15056	BRAF	P28482	MAPK1	S335	S337L	337	Missense	proximal	2	no	14.911	14.791	EPSD	COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P15056	BRAF	P28482	MAPK1	S335	S337P	337	Missense	proximal	2	no	14.911	14.938	EPSD	COSMIC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P15056	BRAF	P28482	MAPK1	T401	P407L	407	Missense	distal	6	no	14.262	13.856	PhosphoSitePlus;EPSD	COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P15056	BRAF	P28482	MAPK1	T401	A404V	404	Missense	distal	3	no	14.262	14.241	PhosphoSitePlus;EPSD	COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P15056	BRAF	P28482	MAPK1	T401	P403L	403	Missense	proximal	2	no	14.262	14.115	PhosphoSitePlus;EPSD	COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P15056	BRAF	P28482	MAPK1	T401	A400S	400	Missense	proximal	-1	no	14.262	14.256	PhosphoSitePlus;EPSD	COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P15056	BRAF	P28482	MAPK1	S419	G421R	421	Missense	proximal	2	no	14.619	14.714	EPSD	COSMIC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P15056	BRAF	P28482	MAPK1	S419	G421V	421	Missense	proximal	2	no	14.619	14.547	EPSD	COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P15056	BRAF	P28482	MAPK1	S419	V413M	413	Missense	distal	-6	no	14.619	14.622	EPSD	COSMIC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P15056	BRAF	P28482	MAPK1	S419	P422A	422	Missense	distal	3	no	14.619	14.697	EPSD	COSMIC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P15056	BRAF	P28482	MAPK1	S419	N412S	412	Missense	distal	-7	no	14.619	14.617	EPSD	COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P15056	BRAF	P28482	MAPK1	S419	L416S	416	Missense	distal	-3	no	14.619	14.826	EPSD	COSMIC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P15056	BRAF	P28482	MAPK1	S419	P420S	420	Missense	proximal	1	no	14.619	5.224	EPSD	COSMIC	8.102	Loss
CMGC_MAPK_ERK1_MAPK1_ST	P15056	BRAF	P28482	MAPK1	S419	R424L	424	Missense	distal	5	no	14.619	14.356	EPSD	COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P15056	BRAF	P28482	MAPK1	S602	R603Q	603	Missense	proximal	1	no	7.007	8.168	EPSD	COSMIC	8.102	Gain
CMGC_MAPK_ERK1_MAPK1_ST	P15056	BRAF	P28482	MAPK1	S675	K680N	680	Missense	distal	5	no	15.348	15.378	EPSD	COSMIC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P15056	BRAF	P28482	MAPK1	S675	P676S	676	Missense	proximal	1	no	15.348	5.953	EPSD	COSMIC	8.102	Loss
CMGC_MAPK_ERK1_MAPK1_ST	P15056	BRAF	P28482	MAPK1	S675	R682W	682	Missense	distal	7	no	15.348	16.319	EPSD	COSMIC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P15056	BRAF	P28482	MAPK1	S675	L674Q	674	Missense	proximal	-1	no	15.348	15.367	EPSD	COSMIC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P15056	BRAF	P28482	MAPK1	S675	R682Q	682	Missense	distal	7	no	15.348	15.463	EPSD	COSMIC;CCLE	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P15056	BRAF	P28482	MAPK1	S675	Y673C	673	Missense	proximal	-2	no	15.348	13.699	EPSD	COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P15056	BRAF	P28482	MAPK1	S675	S679N	679	Missense	distal	4	no	15.348	15.310	EPSD	COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P15056	BRAF	P28482	MAPK1	S750	I755V	755	Missense	distal	5	no	14.197	14.372	EPSD	COSMIC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P15056	BRAF	P28482	MAPK1	S750	C748Y	748	Missense	proximal	-2	no	14.197	15.846	EPSD	COSMIC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P15056	BRAF	P28482	MAPK1	T753	Y760C	760	Missense	distal	7	no	19.816	19.957	EPSD;PhosphoSitePlus	COSMIC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P15056	BRAF	P28482	MAPK1	T753	G759R	759	Missense	distal	6	no	19.816	19.786	EPSD;PhosphoSitePlus	COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P15056	BRAF	P28482	MAPK1	T753	I755V	755	Missense	proximal	2	no	19.816	19.933	EPSD;PhosphoSitePlus	COSMIC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P15056	BRAF	P28482	MAPK1	T753	G758E	758	Missense	distal	5	no	19.816	19.791	EPSD;PhosphoSitePlus	COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P15056	BRAF	P28482	MAPK1	T753	C748Y	748	Missense	distal	-5	no	19.816	19.744	EPSD;PhosphoSitePlus	COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P04626	ERBB2	P28482	MAPK1	S196	S189C	189	Missense	distal	-7	no	17.483	17.450	EPSD	COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P04626	ERBB2	P28482	MAPK1	S196	C195Y	195	Missense	proximal	-1	no	17.483	17.530	EPSD	COSMIC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P04626	ERBB2	P28482	MAPK1	S196	P197L	197	Missense	proximal	1	no	17.483	8.673	EPSD	COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P04626	ERBB2	P28482	MAPK1	S196	P197S	197	Missense	proximal	1	no	17.483	8.088	EPSD	COSMIC	8.102	Loss
CMGC_MAPK_ERK1_MAPK1_ST	P04626	ERBB2	P28482	MAPK1	S196	G201V	201	Missense	distal	5	no	17.483	17.360	EPSD	COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P04626	ERBB2	P28482	MAPK1	S196	K200N	200	Missense	distal	4	no	17.483	17.458	EPSD	COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P04626	ERBB2	P28482	MAPK1	S196	S196P	196	Missense	central	0	yes	17.483	0.000	EPSD	COSMIC	8.102	Loss
CMGC_MAPK_ERK1_MAPK1_ST	P04626	ERBB2	P28482	MAPK1	S196	R190L	190	Missense	distal	-6	no	17.483	17.383	EPSD	COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P04626	ERBB2	P28482	MAPK1	S196	R190Q	190	Missense	distal	-6	no	17.483	17.460	EPSD	COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P04626	ERBB2	P28482	MAPK1	S196	M198T	198	Missense	proximal	2	no	17.483	17.623	EPSD	COSMIC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P04626	ERBB2	P28482	MAPK1	S196	A191P	191	Missense	distal	-5	no	17.483	17.358	EPSD	COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P04626	ERBB2	P28482	MAPK1	S196	K200R	200	Missense	distal	4	no	17.483	17.473	EPSD	COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P04626	ERBB2	P28482	MAPK1	S196	A191V	191	Missense	distal	-5	no	17.483	17.454	EPSD	COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P04626	ERBB2	P28482	MAPK1	S196	A191S	191	Missense	distal	-5	no	17.483	17.432	EPSD	COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P04626	ERBB2	P28482	MAPK1	T701	E695G	695	Missense	distal	-6	no	17.817	17.764	PhosphoSitePlus	COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P04626	ERBB2	P28482	MAPK1	T701	G704R	704	Missense	distal	3	no	17.817	17.780	PhosphoSitePlus	COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P04626	ERBB2	P28482	MAPK1	T701	P702L	702	Missense	proximal	1	no	17.817	9.008	PhosphoSitePlus	COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P04626	ERBB2	P28482	MAPK1	T701	A705V	705	Missense	distal	4	no	17.817	17.812	PhosphoSitePlus	COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P04626	ERBB2	P28482	MAPK1	T701	E698V	698	Missense	distal	-3	no	17.817	17.690	PhosphoSitePlus	COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P04626	ERBB2	P28482	MAPK1	T701	P699L	699	Missense	proximal	-2	no	17.817	15.900	PhosphoSitePlus	COSMIC;CCLE	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P04626	ERBB2	P28482	MAPK1	T701	E698K	698	Missense	distal	-3	no	17.817	17.740	PhosphoSitePlus	COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P04626	ERBB2	P28482	MAPK1	T759	S760F	760	Missense	proximal	1	no	5.433	8.258	EPSD	COSMIC	8.102	Gain
CMGC_MAPK_ERK1_MAPK1_ST	P04626	ERBB2	P28482	MAPK1	T759	S760P	760	Missense	proximal	1	no	5.433	14.828	EPSD	COSMIC	8.102	Gain
CMGC_MAPK_ERK1_MAPK1_ST	P04626	ERBB2	P28482	MAPK1	S760	V754M	754	Missense	distal	-6	no	14.838	14.840	EPSD	COSMIC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P04626	ERBB2	P28482	MAPK1	S760	L755A	755	Missense	distal	-5	no	14.838	14.814	EPSD	COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P04626	ERBB2	P28482	MAPK1	S760	L755P	755	Missense	distal	-5	no	14.838	14.689	EPSD	COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P04626	ERBB2	P28482	MAPK1	S760	S760F	760	Missense	central	0	yes	14.838	0.000	EPSD	COSMIC	8.102	Loss
CMGC_MAPK_ERK1_MAPK1_ST	P04626	ERBB2	P28482	MAPK1	S760	E757K	757	Missense	distal	-3	no	14.838	14.760	EPSD	COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P04626	ERBB2	P28482	MAPK1	S760	E757D	757	Missense	distal	-3	no	14.838	14.889	EPSD	COSMIC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P04626	ERBB2	P28482	MAPK1	S760	S760P	760	Missense	central	0	yes	14.838	0.000	EPSD	COSMIC	8.102	Loss
CMGC_MAPK_ERK1_MAPK1_ST	P04626	ERBB2	P28482	MAPK1	S760	P761L	761	Missense	proximal	1	no	14.838	6.028	EPSD	COSMIC	8.102	Loss
CMGC_MAPK_ERK1_MAPK1_ST	P04626	ERBB2	P28482	MAPK1	S760	L755R	755	Missense	distal	-5	no	14.838	14.736	EPSD	COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P04626	ERBB2	P28482	MAPK1	S760	L755F	755	Missense	distal	-5	no	14.838	14.851	EPSD	COSMIC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P04626	ERBB2	P28482	MAPK1	S779	L785P	785	Missense	distal	6	no	13.904	14.310	EPSD	COSMIC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P04626	ERBB2	P28482	MAPK1	S779	R784H	784	Missense	distal	5	no	13.904	13.727	EPSD	COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P04626	ERBB2	P28482	MAPK1	S779	L786M	786	Missense	distal	7	no	13.904	13.975	EPSD	COSMIC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P04626	ERBB2	P28482	MAPK1	S779	G776C	776	Missense	distal	-3	no	13.904	13.389	EPSD	COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P04626	ERBB2	P28482	MAPK1	S779	R784S	784	Missense	distal	5	no	13.904	13.872	EPSD	COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P04626	ERBB2	P28482	MAPK1	S779	L785R	785	Missense	distal	6	no	13.904	14.203	EPSD	COSMIC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P04626	ERBB2	P28482	MAPK1	S779	S779P	779	Missense	central	0	yes	13.904	0.000	EPSD	COSMIC	8.102	Loss
CMGC_MAPK_ERK1_MAPK1_ST	P04626	ERBB2	P28482	MAPK1	S779	P780L	780	Missense	proximal	1	no	13.904	5.094	EPSD	COSMIC	8.102	Loss
CMGC_MAPK_ERK1_MAPK1_ST	P04626	ERBB2	P28482	MAPK1	S779	V773M	773	Missense	distal	-6	no	13.904	13.906	EPSD	COSMIC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P04626	ERBB2	P28482	MAPK1	S779	P780T	780	Missense	proximal	1	no	13.904	5.405	EPSD	COSMIC	8.102	Loss
CMGC_MAPK_ERK1_MAPK1_ST	P04626	ERBB2	P28482	MAPK1	S779	L786V	786	Missense	distal	7	no	13.904	13.898	EPSD	COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P04626	ERBB2	P28482	MAPK1	S779	Y781C	781	Missense	proximal	2	no	13.904	13.840	EPSD	COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P04626	ERBB2	P28482	MAPK1	S779	L785F	785	Missense	distal	6	no	13.904	13.870	EPSD	COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P04626	ERBB2	P28482	MAPK1	S779	V777E	777	Missense	proximal	-2	no	13.904	13.397	EPSD	COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P04626	ERBB2	P28482	MAPK1	S779	G778D	778	Missense	proximal	-1	no	13.904	13.903	EPSD	COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P04626	ERBB2	P28482	MAPK1	S779	V773A	773	Missense	distal	-6	no	13.904	13.951	EPSD	COSMIC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P04626	ERBB2	P28482	MAPK1	S779	P780S	780	Missense	proximal	1	no	13.904	4.509	EPSD	COSMIC	8.102	Loss
CMGC_MAPK_ERK1_MAPK1_ST	P04626	ERBB2	P28482	MAPK1	S779	A775G	775	Missense	distal	-4	no	13.904	13.847	EPSD	COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P04626	ERBB2	P28482	MAPK1	S779	V782A	782	Missense	distal	3	no	13.904	13.925	EPSD	COSMIC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P04626	ERBB2	P28482	MAPK1	S779	G776L	776	Missense	distal	-3	no	13.904	13.709	EPSD	COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P04626	ERBB2	P28482	MAPK1	S779	V782M	782	Missense	distal	3	no	13.904	13.931	EPSD	COSMIC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P04626	ERBB2	P28482	MAPK1	S998	P996S	996	Missense	proximal	-2	no	17.256	14.421	EPSD	COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P04626	ERBB2	P28482	MAPK1	S1050	S1051F	1051	Missense	proximal	1	no	5.833	8.658	EPSD	COSMIC	8.102	Gain
CMGC_MAPK_ERK1_MAPK1_ST	P04626	ERBB2	P28482	MAPK1	T1060	L1061P	1061	Missense	proximal	1	no	6.715	15.525	EPSD	COSMIC	8.102	Gain
CMGC_MAPK_ERK1_MAPK1_ST	P04626	ERBB2	P28482	MAPK1	S1073	S1078F	1078	Missense	distal	5	no	16.192	15.995	EPSD	COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P04626	ERBB2	P28482	MAPK1	S1073	P1074A	1074	Missense	proximal	1	no	16.192	8.562	EPSD	COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P04626	ERBB2	P28482	MAPK1	S1107	P1102S	1102	Missense	distal	-5	no	11.604	11.678	EPSD	COSMIC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P04626	ERBB2	P28482	MAPK1	S1107	D1105N	1105	Missense	proximal	-2	no	11.604	12.085	EPSD	COSMIC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P04626	ERBB2	P28482	MAPK1	S1107	S1107N	1107	Missense	central	0	yes	11.604	0.000	EPSD	COSMIC	8.102	Loss
CMGC_MAPK_ERK1_MAPK1_ST	P04626	ERBB2	P28482	MAPK1	S1107	E1114G	1114	Missense	distal	7	no	11.604	11.731	EPSD	COSMIC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P04626	ERBB2	P28482	MAPK1	S1107	D1105Y	1105	Missense	proximal	-2	no	11.604	12.788	EPSD	COSMIC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P04626	ERBB2	P28482	MAPK1	S1107	R1111Q	1111	Missense	distal	4	no	11.604	11.529	EPSD	COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P04626	ERBB2	P28482	MAPK1	S1107	E1114Q	1114	Missense	distal	7	no	11.604	11.782	EPSD	COSMIC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P04626	ERBB2	P28482	MAPK1	S1134	A1129V	1129	Missense	distal	-5	no	15.624	15.595	EPSD	COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P04626	ERBB2	P28482	MAPK1	S1134	C1133S	1133	Missense	proximal	-1	no	15.624	15.703	EPSD	COSMIC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P04626	ERBB2	P28482	MAPK1	S1151	D1144N	1144	Missense	distal	-7	no	16.299	16.300	EPSD	COSMIC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P04626	ERBB2	P28482	MAPK1	S1151	P1156H	1156	Missense	distal	5	no	16.299	16.172	EPSD	COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P04626	ERBB2	P28482	MAPK1	S1151	R1146W	1146	Missense	distal	-5	no	16.299	16.575	EPSD	COSMIC;GDSC;CCLE	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P04626	ERBB2	P28482	MAPK1	S1151	R1153L	1153	Missense	proximal	2	no	16.299	16.038	EPSD	COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P04626	ERBB2	P28482	MAPK1	S1151	D1144H	1144	Missense	distal	-7	no	16.299	16.286	EPSD	COSMIC;GDSC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P04626	ERBB2	P28482	MAPK1	S1151	P1147S	1147	Missense	distal	-4	no	16.299	16.215	EPSD	COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P04626	ERBB2	P28482	MAPK1	S1151	S1151L	1151	Missense	central	0	yes	16.299	0.000	EPSD	COSMIC	8.102	Loss
CMGC_MAPK_ERK1_MAPK1_ST	P04626	ERBB2	P28482	MAPK1	T1172	L1167F	1167	Missense	distal	-5	no	8.440	8.454	EPSD	COSMIC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P04626	ERBB2	P28482	MAPK1	T1172	L1173P	1173	Missense	proximal	1	no	8.440	17.250	EPSD	COSMIC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P04626	ERBB2	P28482	MAPK1	T1172	S1174F	1174	Missense	proximal	2	no	8.440	8.309	EPSD	COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P04626	ERBB2	P28482	MAPK1	T1172	P1170A	1170	Missense	proximal	-2	no	8.440	5.294	EPSD	COSMIC	8.102	Loss
CMGC_MAPK_ERK1_MAPK1_ST	P04626	ERBB2	P28482	MAPK1	T1172	G1176W	1176	Missense	distal	4	no	8.440	8.183	EPSD	COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P04626	ERBB2	P28482	MAPK1	T1172	T1166I	1166	Missense	distal	-6	no	8.440	8.362	EPSD	COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P04626	ERBB2	P28482	MAPK1	T1172	K1171M	1171	Missense	proximal	-1	no	8.440	8.377	EPSD	COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P04626	ERBB2	P28482	MAPK1	T1172	P1175R	1175	Missense	distal	3	no	8.440	8.486	EPSD	COSMIC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P04626	ERBB2	P28482	MAPK1	T1172	K1177E	1177	Missense	distal	5	no	8.440	8.500	EPSD	COSMIC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P04626	ERBB2	P28482	MAPK1	T1172	L1167V	1167	Missense	distal	-5	no	8.440	8.387	EPSD	COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P04626	ERBB2	P28482	MAPK1	S1174	L1167F	1167	Missense	distal	-7	no	15.036	15.023	EPSD	COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P04626	ERBB2	P28482	MAPK1	S1174	L1173P	1173	Missense	proximal	-1	no	15.036	15.095	EPSD	COSMIC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P04626	ERBB2	P28482	MAPK1	S1174	S1174F	1174	Missense	central	0	yes	15.036	0.000	EPSD	COSMIC	8.102	Loss
CMGC_MAPK_ERK1_MAPK1_ST	P04626	ERBB2	P28482	MAPK1	S1174	P1170A	1170	Missense	distal	-4	no	15.036	14.742	EPSD	COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P04626	ERBB2	P28482	MAPK1	S1174	G1176W	1176	Missense	proximal	2	no	15.036	14.762	EPSD	COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P04626	ERBB2	P28482	MAPK1	S1174	K1171M	1171	Missense	distal	-3	no	15.036	14.856	EPSD	COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P04626	ERBB2	P28482	MAPK1	S1174	P1175R	1175	Missense	proximal	1	no	15.036	5.381	EPSD	COSMIC	8.102	Loss
CMGC_MAPK_ERK1_MAPK1_ST	P04626	ERBB2	P28482	MAPK1	S1174	K1177E	1177	Missense	distal	3	no	15.036	15.029	EPSD	COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P04626	ERBB2	P28482	MAPK1	S1174	L1167V	1167	Missense	distal	-7	no	15.036	15.029	EPSD	COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P04626	ERBB2	P28482	MAPK1	T1198	G1201V	1201	Missense	distal	3	no	15.433	15.407	EPSD	COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P04626	ERBB2	P28482	MAPK1	T1198	G1202V	1202	Missense	distal	4	no	15.433	15.383	EPSD	COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P04626	ERBB2	P28482	MAPK1	T1198	E1195K	1195	Missense	distal	-3	no	15.433	15.355	EPSD	COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P04626	ERBB2	P28482	MAPK1	T1198	L1197F	1197	Missense	proximal	-1	no	15.433	15.403	EPSD	COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P04626	ERBB2	P28482	MAPK1	T1198	V1191M	1191	Missense	distal	-7	no	15.433	15.430	EPSD	COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P04626	ERBB2	P28482	MAPK1	T1198	Q1200H	1200	Missense	proximal	2	no	15.433	15.481	EPSD	COSMIC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P04626	ERBB2	P28482	MAPK1	T1198	A1204T	1204	Missense	distal	6	no	15.433	15.519	EPSD	COSMIC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P04626	ERBB2	P28482	MAPK1	S1214	P1211H	1211	Missense	distal	-3	no	13.860	13.510	EPSD	COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P04626	ERBB2	P28482	MAPK1	S1214	P1210S	1210	Missense	distal	-4	no	13.860	13.776	EPSD	COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P04626	ERBB2	P28482	MAPK1	S1214	A1216D	1216	Missense	proximal	2	no	13.860	13.973	EPSD	COSMIC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P04626	ERBB2	P28482	MAPK1	S1214	A1212G	1212	Missense	proximal	-2	no	13.860	13.812	EPSD	COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P04626	ERBB2	P28482	MAPK1	S1235	E1229Q	1229	Missense	distal	-6	no	8.966	8.940	EPSD	COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P04626	ERBB2	P28482	MAPK1	S1235	T1242M	1242	Missense	distal	7	no	8.966	9.174	EPSD	COSMIC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P04626	ERBB2	P28482	MAPK1	S1235	E1229D	1229	Missense	distal	-6	no	8.966	8.978	EPSD	COSMIC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P04626	ERBB2	P28482	MAPK1	S1235	R1230Q	1230	Missense	distal	-5	no	8.966	9.044	EPSD	COSMIC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P04626	ERBB2	P28482	MAPK1	S1235	P1233L	1233	Missense	proximal	-2	no	8.966	7.049	EPSD	COSMIC	8.102	Loss
CMGC_MAPK_ERK1_MAPK1_ST	P04626	ERBB2	P28482	MAPK1	T1236	E1229Q	1229	Missense	distal	-7	no	10.749	10.747	EPSD	COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P04626	ERBB2	P28482	MAPK1	T1236	T1242M	1242	Missense	distal	6	no	10.749	10.526	EPSD	COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P04626	ERBB2	P28482	MAPK1	T1236	E1229D	1229	Missense	distal	-7	no	10.749	10.741	EPSD	COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P04626	ERBB2	P28482	MAPK1	T1236	R1230Q	1230	Missense	distal	-6	no	10.749	10.726	EPSD	COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P04626	ERBB2	P28482	MAPK1	T1236	P1233L	1233	Missense	distal	-3	no	10.749	10.365	EPSD	COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P04626	ERBB2	P28482	MAPK1	T1240	N1245D	1245	Missense	distal	5	no	16.539	16.637	EPSD	COSMIC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P04626	ERBB2	P28482	MAPK1	T1240	E1244D	1244	Missense	distal	4	no	16.539	16.469	EPSD	COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P04626	ERBB2	P28482	MAPK1	T1240	T1242M	1242	Missense	proximal	2	no	16.539	16.399	EPSD	COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P04626	ERBB2	P28482	MAPK1	T1240	P1233L	1233	Missense	distal	-7	no	16.539	16.527	EPSD	COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P04626	ERBB2	P28482	MAPK1	T1242	N1245D	1245	Missense	distal	3	no	9.550	9.646	EPSD	COSMIC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P04626	ERBB2	P28482	MAPK1	T1242	E1244D	1244	Missense	proximal	2	no	9.550	9.602	EPSD	COSMIC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P04626	ERBB2	P28482	MAPK1	T1242	T1242M	1242	Missense	central	0	yes	9.550	0.000	EPSD	COSMIC	8.102	Loss
CMGC_MAPK_ERK1_MAPK1_ST	P36956	SREBF1	P28482	MAPK1	T105	P99S	99	Missense	distal	-6	no	13.491	13.465	EPSD	COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P36956	SREBF1	P28482	MAPK1	T105	S112A	112	Missense	distal	7	no	13.491	13.673	EPSD	COSMIC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P36956	SREBF1	P28482	MAPK1	T105	P111L	111	Missense	distal	6	no	13.491	13.085	EPSD	COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P36956	SREBF1	P28482	MAPK1	T105	Y110C	110	Missense	distal	5	no	13.491	13.380	EPSD	COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P36956	SREBF1	P28482	MAPK1	T105	P106H	106	Missense	proximal	1	no	13.491	5.668	EPSD	COSMIC	8.102	Loss
CMGC_MAPK_ERK1_MAPK1_ST	P36956	SREBF1	P28482	MAPK1	S117	K123E	123	Missense	distal	6	no	13.022	12.998	EPSD;PhosphoSitePlus	COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P36956	SREBF1	P28482	MAPK1	S117	S112A	112	Missense	distal	-5	no	13.022	13.072	EPSD;PhosphoSitePlus	COSMIC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P36956	SREBF1	P28482	MAPK1	S117	P111L	111	Missense	distal	-6	no	13.022	12.930	EPSD;PhosphoSitePlus	COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P36956	SREBF1	P28482	MAPK1	S117	Y110C	110	Missense	distal	-7	no	13.022	13.020	EPSD;PhosphoSitePlus	COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P36956	SREBF1	P28482	MAPK1	S117	G119W	119	Missense	proximal	2	no	13.022	12.748	EPSD;PhosphoSitePlus	COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P36956	SREBF1	P28482	MAPK1	T426	E420K	420	Missense	distal	-6	no	11.508	11.482	EPSD	COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P36956	SREBF1	P28482	MAPK1	T426	D423G	423	Missense	distal	-3	no	11.508	11.448	EPSD	COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P36956	SREBF1	P28482	MAPK1	S434	P440H	440	Missense	distal	6	no	13.625	13.319	EPSD	COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P36956	SREBF1	P28482	MAPK1	S439	L443F	443	Missense	distal	4	no	14.669	14.601	EPSD	COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P36956	SREBF1	P28482	MAPK1	S439	P440H	440	Missense	proximal	1	no	14.669	6.845	EPSD	COSMIC	8.102	Loss
CMGC_MAPK_ERK1_MAPK1_ST	P36956	SREBF1	P28482	MAPK1	S461	G454D	454	Missense	distal	-7	no	18.829	18.844	EPSD	COSMIC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P36956	SREBF1	P28482	MAPK1	S461	P459H	459	Missense	proximal	-2	no	18.829	16.074	EPSD	COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P36956	SREBF1	P28482	MAPK1	S524	S520N	520	Missense	distal	-4	no	17.046	17.087	EPSD	COSMIC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P36956	SREBF1	P28482	MAPK1	S524	G531A	531	Missense	distal	7	no	17.046	17.158	EPSD	COSMIC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P36956	SREBF1	P28482	MAPK1	S524	H523N	523	Missense	proximal	-1	no	17.046	17.094	EPSD	COSMIC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P36956	SREBF1	P28482	MAPK1	S1049	T1051I	1051	Missense	proximal	2	no	12.854	12.734	EPSD	COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P36956	SREBF1	P28482	MAPK1	S1049	A1046V	1046	Missense	distal	-3	no	12.854	12.914	EPSD	COSMIC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P36956	SREBF1	P28482	MAPK1	S1049	G1047W	1047	Missense	proximal	-2	no	12.854	13.307	EPSD	COSMIC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P10636	MAPT	P28482	MAPK1	T69	E62K	62	Missense	distal	-7	no	14.584	14.577	EPSD	COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P10636	MAPT	P28482	MAPK1	T111	I108V	108	Missense	distal	-3	no	12.736	12.870	EPSD	COSMIC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P10636	MAPT	P28482	MAPK1	T111	G107R	107	Missense	distal	-4	no	12.736	12.996	EPSD	COSMIC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P10636	MAPT	P28482	MAPK1	S228	S227N	227	Missense	proximal	-1	no	14.224	14.273	EPSD	COSMIC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P10636	MAPT	P28482	MAPK1	S228	S227I	227	Missense	proximal	-1	no	14.224	14.201	EPSD	COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P10636	MAPT	P28482	MAPK1	S228	E226K	226	Missense	proximal	-2	no	14.224	14.184	EPSD	COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P10636	MAPT	P28482	MAPK1	S228	Q230R	230	Missense	proximal	2	no	14.224	14.515	EPSD	COSMIC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P10636	MAPT	P28482	MAPK1	S228	P233S	233	Missense	distal	5	no	14.224	14.242	EPSD	COSMIC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P10636	MAPT	P28482	MAPK1	S228	D225E	225	Missense	distal	-3	no	14.224	14.173	EPSD	COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P10636	MAPT	P28482	MAPK1	S228	S227G	227	Missense	proximal	-1	no	14.224	14.213	EPSD	COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P10636	MAPT	P28482	MAPK1	S228	S235L	235	Missense	distal	7	no	14.224	14.512	EPSD	COSMIC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P10636	MAPT	P28482	MAPK1	S232	S227N	227	Missense	distal	-5	no	15.028	14.979	EPSD	COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P10636	MAPT	P28482	MAPK1	S232	S227I	227	Missense	distal	-5	no	15.028	15.163	EPSD	COSMIC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P10636	MAPT	P28482	MAPK1	S232	A237T	237	Missense	distal	5	no	15.028	15.114	EPSD	COSMIC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P10636	MAPT	P28482	MAPK1	S232	E226K	226	Missense	distal	-6	no	15.028	15.002	EPSD	COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P10636	MAPT	P28482	MAPK1	S232	Q230R	230	Missense	proximal	-2	no	15.028	16.203	EPSD	COSMIC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P10636	MAPT	P28482	MAPK1	S232	P233S	233	Missense	proximal	1	no	15.028	5.633	EPSD	COSMIC	8.102	Loss
CMGC_MAPK_ERK1_MAPK1_ST	P10636	MAPT	P28482	MAPK1	S232	S238F	238	Missense	distal	6	no	15.028	14.587	EPSD	COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P10636	MAPT	P28482	MAPK1	S232	D225E	225	Missense	distal	-7	no	15.028	15.036	EPSD	COSMIC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P10636	MAPT	P28482	MAPK1	S232	S227G	227	Missense	distal	-5	no	15.028	15.021	EPSD	COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P10636	MAPT	P28482	MAPK1	S232	S235L	235	Missense	distal	3	no	15.028	15.048	EPSD	COSMIC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P10636	MAPT	P28482	MAPK1	S238	A237T	237	Missense	proximal	-1	no	15.270	15.265	EPSD	COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P10636	MAPT	P28482	MAPK1	S238	A240S	240	Missense	proximal	2	no	15.270	15.372	EPSD	COSMIC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P10636	MAPT	P28482	MAPK1	S238	D242N	242	Missense	distal	4	no	15.270	15.330	EPSD	COSMIC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P10636	MAPT	P28482	MAPK1	S238	R244W	244	Missense	distal	6	no	15.270	14.347	EPSD	COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P10636	MAPT	P28482	MAPK1	S238	S238P	238	Missense	central	0	yes	15.270	0.000	EPSD	COSMIC	8.102	Loss
CMGC_MAPK_ERK1_MAPK1_ST	P10636	MAPT	P28482	MAPK1	S238	P233S	233	Missense	distal	-5	no	15.270	15.344	EPSD	COSMIC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P10636	MAPT	P28482	MAPK1	S238	S238F	238	Missense	central	0	yes	15.270	0.000	EPSD	COSMIC	8.102	Loss
CMGC_MAPK_ERK1_MAPK1_ST	P10636	MAPT	P28482	MAPK1	S238	G243D	243	Missense	distal	5	no	15.270	15.314	EPSD	COSMIC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P10636	MAPT	P28482	MAPK1	S238	S235L	235	Missense	distal	-3	no	15.270	15.063	EPSD	COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P10636	MAPT	P28482	MAPK1	T248	A250T	250	Missense	proximal	2	no	9.386	9.465	EPSD	COSMIC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P10636	MAPT	P28482	MAPK1	T248	A250G	250	Missense	proximal	2	no	9.386	9.534	EPSD	COSMIC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P10636	MAPT	P28482	MAPK1	T248	D242N	242	Missense	distal	-6	no	9.386	9.341	EPSD	COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P10636	MAPT	P28482	MAPK1	T248	R244W	244	Missense	distal	-4	no	9.386	8.444	EPSD	COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P10636	MAPT	P28482	MAPK1	T248	G243D	243	Missense	distal	-5	no	9.386	9.389	EPSD	COSMIC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P10636	MAPT	P28482	MAPK1	S411	L410F	410	Missense	proximal	-1	no	14.042	14.012	EPSD	COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P10636	MAPT	P28482	MAPK1	S411	P412S	412	Missense	proximal	1	no	14.042	4.647	EPSD	COSMIC	8.102	Loss
CMGC_MAPK_ERK1_MAPK1_ST	P10636	MAPT	P28482	MAPK1	T416	L410F	410	Missense	distal	-6	no	13.113	13.095	EPSD	COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P10636	MAPT	P28482	MAPK1	T416	P412S	412	Missense	distal	-4	no	13.113	13.029	EPSD	COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P10636	MAPT	P28482	MAPK1	S438	S443Y	443	Missense	distal	5	no	19.115	18.827	EPSD	COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P10636	MAPT	P28482	MAPK1	T449	S447P	447	Missense	proximal	-2	no	5.515	8.349	EPSD	COSMIC	8.102	Gain
CMGC_MAPK_ERK1_MAPK1_ST	P10636	MAPT	P28482	MAPK1	T470	T466M	466	Missense	distal	-4	no	14.781	14.629	EPSD	COSMIC;GDSC;CCLE	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P10636	MAPT	P28482	MAPK1	T470	K467T	467	Missense	distal	-3	no	14.781	14.830	EPSD	COSMIC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P10636	MAPT	P28482	MAPK1	T470	P477L	477	Missense	distal	7	no	14.781	15.080	EPSD	COSMIC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P10636	MAPT	P28482	MAPK1	T470	P477S	477	Missense	distal	7	no	14.781	14.792	EPSD	COSMIC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P10636	MAPT	P28482	MAPK1	T492	R487K	487	Missense	distal	-5	no	11.959	11.914	EPSD	COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P10636	MAPT	P28482	MAPK1	T492	K491R	491	Missense	proximal	-1	no	11.959	11.926	EPSD	COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P10636	MAPT	P28482	MAPK1	T492	R487G	487	Missense	distal	-5	no	11.959	11.979	EPSD	COSMIC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P10636	MAPT	P28482	MAPK1	T492	A495T	495	Missense	distal	3	no	11.959	11.942	EPSD	COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P10636	MAPT	P28482	MAPK1	T492	P493L	493	Missense	proximal	1	no	11.959	3.149	EPSD	COSMIC	8.102	Loss
CMGC_MAPK_ERK1_MAPK1_ST	P10636	MAPT	P28482	MAPK1	T498	K491R	491	Missense	distal	-7	no	17.714	17.711	EPSD	COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P10636	MAPT	P28482	MAPK1	T498	A495T	495	Missense	distal	-3	no	17.714	17.872	EPSD	COSMIC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P10636	MAPT	P28482	MAPK1	T498	P493L	493	Missense	distal	-5	no	17.714	17.863	EPSD	COSMIC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P10636	MAPT	P28482	MAPK1	S516	G521V	521	Missense	distal	5	no	15.969	15.846	EPSD	COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P10636	MAPT	P28482	MAPK1	S516	G518V	518	Missense	proximal	2	no	15.969	15.897	EPSD	COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P10636	MAPT	P28482	MAPK1	S516	R511C	511	Missense	distal	-5	no	15.969	16.199	EPSD	COSMIC;CCLE	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P10636	MAPT	P28482	MAPK1	S516	G509V	509	Missense	distal	-7	no	15.969	15.968	EPSD	COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P10636	MAPT	P28482	MAPK1	S519	G521V	521	Missense	proximal	2	no	17.679	17.607	EPSD	COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P10636	MAPT	P28482	MAPK1	S519	R526H	526	Missense	distal	7	no	17.679	17.898	EPSD	COSMIC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P10636	MAPT	P28482	MAPK1	S519	G518V	518	Missense	proximal	-1	no	17.679	17.707	EPSD	COSMIC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P10636	MAPT	P28482	MAPK1	T522	G521V	521	Missense	proximal	-1	no	17.162	17.191	EPSD	COSMIC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P10636	MAPT	P28482	MAPK1	T522	R526H	526	Missense	distal	4	no	17.162	17.021	EPSD	COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P10636	MAPT	P28482	MAPK1	T522	G518V	518	Missense	distal	-4	no	17.162	17.158	EPSD	COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P10636	MAPT	P28482	MAPK1	T522	R528S	528	Missense	distal	6	no	17.162	17.269	EPSD	COSMIC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P10636	MAPT	P28482	MAPK1	S525	R526H	526	Missense	proximal	1	no	7.169	9.000	EPSD	COSMIC	8.102	Gain
CMGC_MAPK_ERK1_MAPK1_ST	P10636	MAPT	P28482	MAPK1	T529	R526H	526	Missense	distal	-3	no	14.924	14.594	EPSD	COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P10636	MAPT	P28482	MAPK1	T529	R528S	528	Missense	proximal	-1	no	14.924	14.900	EPSD	COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P10636	MAPT	P28482	MAPK1	T529	P530S	530	Missense	proximal	1	no	14.924	5.529	EPSD	COSMIC	8.102	Loss
CMGC_MAPK_ERK1_MAPK1_ST	P10636	MAPT	P28482	MAPK1	T529	P536H	536	Missense	distal	7	no	14.924	15.157	EPSD	COSMIC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P10636	MAPT	P28482	MAPK1	T529	P535Q	535	Missense	distal	6	no	14.924	14.636	EPSD	COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P10636	MAPT	P28482	MAPK1	T534	R528S	528	Missense	distal	-6	no	14.012	13.978	EPSD	COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P10636	MAPT	P28482	MAPK1	T534	P530S	530	Missense	distal	-4	no	14.012	13.928	EPSD	COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P10636	MAPT	P28482	MAPK1	T534	P536H	536	Missense	proximal	2	no	14.012	13.882	EPSD	COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P10636	MAPT	P28482	MAPK1	T534	P535Q	535	Missense	proximal	1	no	14.012	5.519	EPSD	COSMIC	8.102	Loss
CMGC_MAPK_ERK1_MAPK1_ST	P10636	MAPT	P28482	MAPK1	T534	E539Q	539	Missense	distal	5	no	14.012	13.918	EPSD	COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P10636	MAPT	P28482	MAPK1	T548	P550S	550	Missense	proximal	2	no	14.989	14.961	EPSD	COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P10636	MAPT	P28482	MAPK1	T548	P553R	553	Missense	distal	5	no	14.989	15.039	EPSD	COSMIC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P10636	MAPT	P28482	MAPK1	T548	P553L	553	Missense	distal	5	no	14.989	14.776	EPSD	COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P10636	MAPT	P28482	MAPK1	T548	P549L	549	Missense	proximal	1	no	14.989	6.179	EPSD	COSMIC	8.102	Loss
CMGC_MAPK_ERK1_MAPK1_ST	P10636	MAPT	P28482	MAPK1	T548	S555F	555	Missense	distal	7	no	14.989	15.336	EPSD	COSMIC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P10636	MAPT	P28482	MAPK1	T548	P553Q	553	Missense	distal	5	no	14.989	14.869	EPSD	COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P10636	MAPT	P28482	MAPK1	S552	P550S	550	Missense	proximal	-2	no	15.339	12.505	EPSD	COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P10636	MAPT	P28482	MAPK1	S552	R559C	559	Missense	distal	7	no	15.339	15.995	EPSD	COSMIC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P10636	MAPT	P28482	MAPK1	S552	P553R	553	Missense	proximal	1	no	15.339	5.685	EPSD	COSMIC	8.102	Loss
CMGC_MAPK_ERK1_MAPK1_ST	P10636	MAPT	P28482	MAPK1	S552	P553L	553	Missense	proximal	1	no	15.339	6.530	EPSD	COSMIC	8.102	Loss
CMGC_MAPK_ERK1_MAPK1_ST	P10636	MAPT	P28482	MAPK1	S552	P549L	549	Missense	distal	-3	no	15.339	14.956	EPSD	COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P10636	MAPT	P28482	MAPK1	S552	S555F	555	Missense	distal	3	no	15.339	15.402	EPSD	COSMIC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P10636	MAPT	P28482	MAPK1	S552	P553Q	553	Missense	proximal	1	no	15.339	6.846	EPSD	COSMIC	8.102	Loss
CMGC_MAPK_ERK1_MAPK1_ST	P10636	MAPT	P28482	MAPK1	T562	V565M	565	Missense	distal	3	no	8.104	8.131	EPSD	COSMIC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P10636	MAPT	P28482	MAPK1	T562	P566S	566	Missense	distal	4	no	8.104	8.093	EPSD	COSMIC	8.102	Loss
CMGC_MAPK_ERK1_MAPK1_ST	P10636	MAPT	P28482	MAPK1	T562	R559C	559	Missense	distal	-3	no	8.104	7.420	EPSD	COSMIC	8.102	Loss
CMGC_MAPK_ERK1_MAPK1_ST	P10636	MAPT	P28482	MAPK1	T562	S555F	555	Missense	distal	-7	no	8.104	8.084	EPSD	COSMIC	8.102	Loss
CMGC_MAPK_ERK1_MAPK1_ST	P10636	MAPT	P28482	MAPK1	S658	D662G	662	Missense	distal	4	no	8.075	8.123	EPSD	COSMIC	8.102	Gain
CMGC_MAPK_ERK1_MAPK1_ST	P10636	MAPT	P28482	MAPK1	S713	E708D	708	Missense	distal	-5	no	15.734	15.778	EPSD	COSMIC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P10636	MAPT	P28482	MAPK1	S713	G706R	706	Missense	distal	-7	no	15.734	15.747	EPSD	COSMIC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P10636	MAPT	P28482	MAPK1	S713	V710M	710	Missense	distal	-3	no	15.734	15.603	EPSD	COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P10636	MAPT	P28482	MAPK1	S713	E708K	708	Missense	distal	-5	no	15.734	15.711	EPSD	COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P10636	MAPT	P28482	MAPK1	S713	V710A	710	Missense	distal	-3	no	15.734	15.674	EPSD	COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P10636	MAPT	P28482	MAPK1	S721	R723W	723	Missense	proximal	2	no	13.576	13.208	EPSD	COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P10636	MAPT	P28482	MAPK1	S721	V728M	728	Missense	distal	7	no	13.576	13.653	EPSD	COSMIC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P10636	MAPT	P28482	MAPK1	S721	V728A	728	Missense	distal	7	no	13.576	13.475	EPSD	COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P10636	MAPT	P28482	MAPK1	S739	G732S	732	Missense	distal	-7	no	18.678	18.692	EPSD	COSMIC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P10636	MAPT	P28482	MAPK1	S739	D735N	735	Missense	distal	-4	no	18.678	18.650	EPSD	COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P10636	MAPT	P28482	MAPK1	S739	G732C	732	Missense	distal	-7	no	18.678	18.659	EPSD	COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P10636	MAPT	P28482	MAPK1	S739	T744M	744	Missense	distal	5	no	18.678	18.547	EPSD	COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P10636	MAPT	P28482	MAPK1	S739	A743T	743	Missense	distal	4	no	18.678	18.658	EPSD	COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P10636	MAPT	P28482	MAPK1	T744	E748K	748	Missense	distal	4	no	8.265	8.279	EPSD	COSMIC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P10636	MAPT	P28482	MAPK1	T744	T744M	744	Missense	central	0	yes	8.265	0.000	EPSD	COSMIC	8.102	Loss
CMGC_MAPK_ERK1_MAPK1_ST	P10636	MAPT	P28482	MAPK1	T744	A743T	743	Missense	proximal	-1	no	8.265	8.260	EPSD	COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P10636	MAPT	P28482	MAPK1	S750	E748K	748	Missense	proximal	-2	no	9.037	8.997	EPSD	COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P10636	MAPT	P28482	MAPK1	S750	T744M	744	Missense	distal	-6	no	9.037	9.003	EPSD	COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P10636	MAPT	P28482	MAPK1	S750	A743T	743	Missense	distal	-7	no	9.037	9.023	EPSD	COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q13541	EIF4EBP1	P28482	MAPK1	S65	L59Q	59	Missense	distal	-6	no	13.530	13.606	PhosphoSitePlus;EPSD	COSMIC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q13541	EIF4EBP1	P28482	MAPK1	S65	M60I	60	Missense	distal	-5	no	13.530	13.586	PhosphoSitePlus;EPSD	COSMIC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q13541	EIF4EBP1	P28482	MAPK1	S65	P72S	72	Missense	distal	7	no	13.530	13.540	PhosphoSitePlus;EPSD	COSMIC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q13541	EIF4EBP1	P28482	MAPK1	S65	R63W	63	Missense	proximal	-2	no	13.530	12.606	PhosphoSitePlus;EPSD	COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q13541	EIF4EBP1	P28482	MAPK1	T70	P72S	72	Missense	proximal	2	no	14.934	14.907	EPSD;PhosphoSitePlus	COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q13541	EIF4EBP1	P28482	MAPK1	T70	R63W	63	Missense	distal	-7	no	14.934	14.884	EPSD;PhosphoSitePlus	COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q13541	EIF4EBP1	P28482	MAPK1	S83	S85F	85	Missense	proximal	2	no	16.492	16.360	EPSD	COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q13541	EIF4EBP1	P28482	MAPK1	S86	S85F	85	Missense	proximal	-1	no	8.587	8.541	EPSD	COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q13541	EIF4EBP1	P28482	MAPK1	S96	N100H	100	Missense	distal	4	no	8.499	8.372	EPSD	COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q13541	EIF4EBP1	P28482	MAPK1	S101	N100H	100	Missense	proximal	-1	no	15.740	15.691	EPSD	COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q13541	EIF4EBP1	P28482	MAPK1	S101	R106L	106	Missense	distal	5	no	15.740	15.477	EPSD	COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q13541	EIF4EBP1	P28482	MAPK1	S112	R106L	106	Missense	distal	-6	no	8.221	8.121	EPSD	COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P49715	CEBPA	P28482	MAPK1	S16	S21G	21	Missense	distal	5	no	10.133	10.114	EPSD	COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P49715	CEBPA	P28482	MAPK1	S16	S21R	21	Missense	distal	5	no	10.133	10.165	EPSD	COSMIC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P49715	CEBPA	P28482	MAPK1	S16	L19Q	19	Missense	distal	3	no	10.133	10.112	EPSD	COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P49715	CEBPA	P28482	MAPK1	S16	A9V	9	Missense	distal	-7	no	10.133	10.117	EPSD	COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P49715	CEBPA	P28482	MAPK1	S16	P14R	14	Missense	proximal	-2	no	10.133	8.315	EPSD	COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P49715	CEBPA	P28482	MAPK1	S16	E10K	10	Missense	distal	-6	no	10.133	10.107	EPSD	COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P49715	CEBPA	P28482	MAPK1	S16	P14L	14	Missense	proximal	-2	no	10.133	8.216	EPSD	COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P49715	CEBPA	P28482	MAPK1	S21	S21G	21	Missense	central	0	yes	16.673	0.000	PhosphoSitePlus	COSMIC	8.102	Loss
CMGC_MAPK_ERK1_MAPK1_ST	P49715	CEBPA	P28482	MAPK1	S21	S21R	21	Missense	central	0	yes	16.673	0.000	PhosphoSitePlus	COSMIC	8.102	Loss
CMGC_MAPK_ERK1_MAPK1_ST	P49715	CEBPA	P28482	MAPK1	S21	L19Q	19	Missense	proximal	-2	no	16.673	15.597	PhosphoSitePlus	COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P49715	CEBPA	P28482	MAPK1	S21	S27R	27	Missense	distal	6	no	16.673	16.566	PhosphoSitePlus	COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P49715	CEBPA	P28482	MAPK1	S21	P14R	14	Missense	distal	-7	no	16.673	16.668	PhosphoSitePlus	COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P49715	CEBPA	P28482	MAPK1	S21	P14L	14	Missense	distal	-7	no	16.673	16.661	PhosphoSitePlus	COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P49715	CEBPA	P28482	MAPK1	S190	P184R	184	Missense	distal	-6	no	9.122	9.130	EPSD	COSMIC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P49715	CEBPA	P28482	MAPK1	S190	P186S	186	Missense	distal	-4	no	9.122	9.038	EPSD	COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P49715	CEBPA	P28482	MAPK1	S190	P183Q	183	Missense	distal	-7	no	9.122	9.125	EPSD	COSMIC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P49715	CEBPA	P28482	MAPK1	S190	P197Q	197	Missense	distal	7	no	9.122	9.252	EPSD	COSMIC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P49715	CEBPA	P28482	MAPK1	T226	G223S	223	Missense	distal	-3	no	12.549	12.561	EPSD	COSMIC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P49715	CEBPA	P28482	MAPK1	T226	P227S	227	Missense	proximal	1	no	12.549	3.154	EPSD	COSMIC	8.102	Loss
CMGC_MAPK_ERK1_MAPK1_ST	P49715	CEBPA	P28482	MAPK1	T226	G223R	223	Missense	distal	-3	no	12.549	12.718	EPSD	COSMIC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P49715	CEBPA	P28482	MAPK1	T226	H224Q	224	Missense	proximal	-2	no	12.549	12.310	EPSD	COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P49715	CEBPA	P28482	MAPK1	T226	P233R	233	Missense	distal	7	no	12.549	12.563	EPSD	COSMIC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P49715	CEBPA	P28482	MAPK1	T230	G223S	223	Missense	distal	-7	no	14.607	14.621	EPSD	COSMIC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P49715	CEBPA	P28482	MAPK1	T230	P227S	227	Missense	distal	-3	no	14.607	14.431	EPSD	COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P49715	CEBPA	P28482	MAPK1	T230	G223R	223	Missense	distal	-7	no	14.607	14.620	EPSD	COSMIC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P49715	CEBPA	P28482	MAPK1	T230	H224Q	224	Missense	distal	-6	no	14.607	14.667	EPSD	COSMIC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P49715	CEBPA	P28482	MAPK1	T230	P233R	233	Missense	distal	3	no	14.607	14.653	EPSD	COSMIC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P49715	CEBPA	P28482	MAPK1	S234	P239A	239	Missense	distal	5	no	16.247	16.106	EPSD	COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P49715	CEBPA	P28482	MAPK1	S234	P227S	227	Missense	distal	-7	no	16.247	16.243	EPSD	COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P49715	CEBPA	P28482	MAPK1	S234	P233R	233	Missense	proximal	-1	no	16.247	16.228	EPSD	COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P49715	CEBPA	P28482	MAPK1	S332	R333P	333	Missense	proximal	1	no	5.176	14.831	EPSD	COSMIC	8.102	Gain
CMGC_MAPK_ERK1_MAPK1_ST	Q96PH1	NOX5	P28482	MAPK1	S544	S547L	547	Missense	distal	3	no	9.731	9.751	EPSD	COSMIC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q96PH1	NOX5	P28482	MAPK1	S544	R537S	537	Missense	distal	-7	no	9.731	9.732	EPSD	COSMIC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q96PH1	NOX5	P28482	MAPK1	S544	M541I	541	Missense	distal	-3	no	9.731	9.727	EPSD	COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q96PH1	NOX5	P28482	MAPK1	S544	K549R	549	Missense	distal	5	no	9.731	9.866	EPSD	COSMIC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q96PH1	NOX5	P28482	MAPK1	S544	V539L	539	Missense	distal	-5	no	9.731	9.784	EPSD	COSMIC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q96PH1	NOX5	P28482	MAPK1	S544	T540I	540	Missense	distal	-4	no	9.731	9.373	EPSD	COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P50548	ERF	P28482	MAPK1	S21	S20L	20	Missense	proximal	-1	no	16.292	16.276	EPSD	COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P50548	ERF	P28482	MAPK1	S21	G23D	23	Missense	proximal	2	no	16.292	16.258	EPSD	COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P50548	ERF	P28482	MAPK1	S24	S20L	20	Missense	distal	-4	no	8.535	8.314	EPSD	COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P50548	ERF	P28482	MAPK1	S24	G23D	23	Missense	proximal	-1	no	8.535	8.534	EPSD	COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P50548	ERF	P28482	MAPK1	S131	P129T	129	Missense	proximal	-2	no	8.784	6.084	EPSD	COSMIC	8.102	Loss
CMGC_MAPK_ERK1_MAPK1_ST	P50548	ERF	P28482	MAPK1	S131	S137L	137	Missense	distal	6	no	8.784	8.377	EPSD	COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P50548	ERF	P28482	MAPK1	S131	P133Q	133	Missense	proximal	2	no	8.784	8.606	EPSD	COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P50548	ERF	P28482	MAPK1	S131	P133T	133	Missense	proximal	2	no	8.784	8.733	EPSD	COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P50548	ERF	P28482	MAPK1	T148	P145H	145	Missense	distal	-3	no	15.729	15.380	EPSD	COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P50548	ERF	P28482	MAPK1	T148	P155T	155	Missense	distal	7	no	15.729	15.892	EPSD	COSMIC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P50548	ERF	P28482	MAPK1	T148	V152M	152	Missense	distal	4	no	15.729	15.641	EPSD	COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P50548	ERF	P28482	MAPK1	T148	F142L	142	Missense	distal	-6	no	15.729	15.748	EPSD	COSMIC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P50548	ERF	P28482	MAPK1	S154	P155T	155	Missense	proximal	1	no	16.150	7.651	EPSD	COSMIC	8.102	Loss
CMGC_MAPK_ERK1_MAPK1_ST	P50548	ERF	P28482	MAPK1	S154	V152M	152	Missense	proximal	-2	no	16.150	14.008	EPSD	COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P50548	ERF	P28482	MAPK1	S154	R160C	160	Missense	distal	6	no	16.150	15.390	EPSD	COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P50548	ERF	P28482	MAPK1	S154	R160H	160	Missense	distal	6	no	16.150	15.951	EPSD	COSMIC;CCLE	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P50548	ERF	P28482	MAPK1	S161	P155T	155	Missense	distal	-6	no	17.079	17.029	EPSD;PhosphoSitePlus	COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P50548	ERF	P28482	MAPK1	S161	S168P	168	Missense	distal	7	no	17.079	17.068	EPSD;PhosphoSitePlus	COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P50548	ERF	P28482	MAPK1	S161	R160C	160	Missense	proximal	-1	no	17.079	16.976	EPSD;PhosphoSitePlus	COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P50548	ERF	P28482	MAPK1	S161	R160H	160	Missense	proximal	-1	no	17.079	17.055	EPSD;PhosphoSitePlus	COSMIC;CCLE	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P50548	ERF	P28482	MAPK1	S167	S168P	168	Missense	proximal	1	no	3.323	12.718	EPSD	COSMIC	8.102	Gain
CMGC_MAPK_ERK1_MAPK1_ST	P50548	ERF	P28482	MAPK1	S170	S168P	168	Missense	proximal	-2	no	6.006	8.840	EPSD	COSMIC	8.102	Gain
CMGC_MAPK_ERK1_MAPK1_ST	P50548	ERF	P28482	MAPK1	S246	P242L	242	Missense	distal	-4	no	16.859	16.555	EPSD;PhosphoSitePlus	COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P50548	ERF	P28482	MAPK1	S246	R239Q	239	Missense	distal	-7	no	16.859	16.867	EPSD;PhosphoSitePlus	COSMIC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P50548	ERF	P28482	MAPK1	S251	G255C	255	Missense	distal	4	no	16.663	16.431	EPSD;PhosphoSitePlus	COSMIC;CCLE	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P50548	ERF	P28482	MAPK1	S327	H325N	325	Missense	proximal	-2	no	13.656	13.591	EPSD	COSMIC;GDSC;CCLE	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P50548	ERF	P28482	MAPK1	S327	R329S	329	Missense	proximal	2	no	13.656	13.514	EPSD	COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P50548	ERF	P28482	MAPK1	S327	R329C	329	Missense	proximal	2	no	13.656	13.283	EPSD	COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P50548	ERF	P28482	MAPK1	T357	T357N	357	Missense	central	0	yes	15.376	0.000	EPSD	COSMIC	8.102	Loss
CMGC_MAPK_ERK1_MAPK1_ST	P50548	ERF	P28482	MAPK1	T357	S363T	363	Missense	distal	6	no	15.376	15.165	EPSD	COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P50548	ERF	P28482	MAPK1	T357	P351L	351	Missense	distal	-6	no	15.376	15.284	EPSD	COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P50548	ERF	P28482	MAPK1	T357	S363L	363	Missense	distal	6	no	15.376	14.969	EPSD	COSMIC;GDSC;CCLE	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P50548	ERF	P28482	MAPK1	T357	S362Y	362	Missense	distal	5	no	15.376	15.087	EPSD	COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P50548	ERF	P28482	MAPK1	S362	S363T	363	Missense	proximal	1	no	8.032	8.928	EPSD	COSMIC	8.102	Gain
CMGC_MAPK_ERK1_MAPK1_ST	P50548	ERF	P28482	MAPK1	S362	S363L	363	Missense	proximal	1	no	8.032	8.617	EPSD	COSMIC;GDSC;CCLE	8.102	Gain
CMGC_MAPK_ERK1_MAPK1_ST	P50548	ERF	P28482	MAPK1	S363	T357N	357	Missense	distal	-6	no	9.166	9.193	EPSD	COSMIC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P50548	ERF	P28482	MAPK1	S363	S365L	365	Missense	proximal	2	no	9.166	9.046	EPSD	COSMIC;GDSC;CCLE	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P50548	ERF	P28482	MAPK1	S363	S363L	363	Missense	central	0	yes	9.166	0.000	EPSD	COSMIC;GDSC;CCLE	8.102	Loss
CMGC_MAPK_ERK1_MAPK1_ST	P50548	ERF	P28482	MAPK1	S363	S362Y	362	Missense	proximal	-1	no	9.166	9.134	EPSD	COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P50548	ERF	P28482	MAPK1	S431	E434K	434	Missense	distal	3	no	8.731	8.738	EPSD	COSMIC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P50548	ERF	P28482	MAPK1	T456	F454L	454	Missense	proximal	-2	no	13.659	14.382	EPSD	COSMIC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P50548	ERF	P28482	MAPK1	T456	D450E	450	Missense	distal	-6	no	13.659	13.647	EPSD	COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P50548	ERF	P28482	MAPK1	T526	G522V	522	Missense	distal	-4	no	18.254	18.250	PhosphoSitePlus;EPSD	COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P50548	ERF	P28482	MAPK1	T526	G522R	522	Missense	distal	-4	no	18.254	18.514	PhosphoSitePlus;EPSD	COSMIC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P50548	ERF	P28482	MAPK1	T526	L525F	525	Missense	proximal	-1	no	18.254	18.224	PhosphoSitePlus;EPSD	COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P50548	ERF	P28482	MAPK1	T526	P524L	524	Missense	proximal	-2	no	18.254	16.337	PhosphoSitePlus;EPSD	COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P50548	ERF	P28482	MAPK1	S531	L525F	525	Missense	distal	-6	no	8.319	8.300	EPSD	COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P50548	ERF	P28482	MAPK1	S531	P524L	524	Missense	distal	-7	no	8.319	8.306	EPSD	COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P50548	ERF	P28482	MAPK1	S532	L525F	525	Missense	distal	-7	no	9.610	9.597	EPSD	COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P50548	ERF	P28482	MAPK1	S542	S542Y	542	Missense	central	0	yes	8.178	0.000	EPSD	COSMIC	8.102	Loss
CMGC_MAPK_ERK1_MAPK1_ST	P50548	ERF	P28482	MAPK1	S542	R546Q	546	Missense	distal	4	no	8.178	8.103	EPSD	COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P49790	NUP153	P28482	MAPK1	T102	T97A	97	Missense	distal	-5	no	13.100	13.122	EPSD	COSMIC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P49790	NUP153	P28482	MAPK1	T118	P123L	123	Missense	distal	5	no	8.475	8.262	EPSD	COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P49790	NUP153	P28482	MAPK1	S240	G237V	237	Missense	distal	-3	no	13.530	13.412	EPSD	COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P49790	NUP153	P28482	MAPK1	S257	F259L	259	Missense	proximal	2	no	12.768	12.780	EPSD;PhosphoSitePlus	COSMIC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P49790	NUP153	P28482	MAPK1	S257	Y260N	260	Missense	distal	3	no	12.768	12.631	EPSD;PhosphoSitePlus	COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P49790	NUP153	P28482	MAPK1	T281	R279Q	279	Missense	proximal	-2	no	13.490	12.315	EPSD	COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P49790	NUP153	P28482	MAPK1	S320	M318I	318	Missense	proximal	-2	no	14.053	16.173	EPSD;PhosphoSitePlus	COSMIC;GDSC;CCLE	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P49790	NUP153	P28482	MAPK1	S320	A325G	325	Missense	distal	5	no	14.053	14.193	EPSD;PhosphoSitePlus	COSMIC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P49790	NUP153	P28482	MAPK1	S320	A323V	323	Missense	distal	3	no	14.053	14.032	EPSD;PhosphoSitePlus	COSMIC;GDSC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P49790	NUP153	P28482	MAPK1	S320	M318T	318	Missense	proximal	-2	no	14.053	15.368	EPSD;PhosphoSitePlus	COSMIC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P49790	NUP153	P28482	MAPK1	S334	S333P	333	Missense	proximal	-1	no	12.980	13.024	EPSD;PhosphoSitePlus	COSMIC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P49790	NUP153	P28482	MAPK1	S334	P335L	335	Missense	proximal	1	no	12.980	4.170	EPSD;PhosphoSitePlus	COSMIC	8.102	Loss
CMGC_MAPK_ERK1_MAPK1_ST	P49790	NUP153	P28482	MAPK1	S334	V332F	332	Missense	proximal	-2	no	12.980	12.212	EPSD;PhosphoSitePlus	COSMIC;GDSC;CCLE	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P49790	NUP153	P28482	MAPK1	S338	S333P	333	Missense	distal	-5	no	15.032	14.958	EPSD;PhosphoSitePlus	COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P49790	NUP153	P28482	MAPK1	S338	P335L	335	Missense	distal	-3	no	15.032	14.648	EPSD;PhosphoSitePlus	COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P49790	NUP153	P28482	MAPK1	S338	V332F	332	Missense	distal	-6	no	15.032	15.008	EPSD;PhosphoSitePlus	COSMIC;GDSC;CCLE	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P49790	NUP153	P28482	MAPK1	S374	T377A	377	Missense	distal	3	no	8.568	8.584	EPSD	COSMIC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P49790	NUP153	P28482	MAPK1	T413	G415R	415	Missense	proximal	2	no	13.522	13.617	EPSD;PhosphoSitePlus	COSMIC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P49790	NUP153	P28482	MAPK1	S491	P485L	485	Missense	distal	-6	no	13.237	13.145	EPSD	COSMIC;GDSC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P49790	NUP153	P28482	MAPK1	S516	S518R	518	Missense	proximal	2	no	12.515	12.657	PhosphoSitePlus;EPSD	COSMIC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P49790	NUP153	P28482	MAPK1	S516	P517S	517	Missense	proximal	1	no	12.515	3.120	PhosphoSitePlus;EPSD	COSMIC	8.102	Loss
CMGC_MAPK_ERK1_MAPK1_ST	P49790	NUP153	P28482	MAPK1	S516	P523S	523	Missense	distal	7	no	12.515	12.526	PhosphoSitePlus;EPSD	COSMIC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P49790	NUP153	P28482	MAPK1	S516	S522F	522	Missense	distal	6	no	12.515	12.075	PhosphoSitePlus;EPSD	COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P49790	NUP153	P28482	MAPK1	S522	S518R	518	Missense	distal	-4	no	14.700	14.694	EPSD;PhosphoSitePlus	COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P49790	NUP153	P28482	MAPK1	S522	P517S	517	Missense	distal	-5	no	14.700	14.774	EPSD;PhosphoSitePlus	COSMIC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P49790	NUP153	P28482	MAPK1	S522	P523S	523	Missense	proximal	1	no	14.700	5.305	EPSD;PhosphoSitePlus	COSMIC	8.102	Loss
CMGC_MAPK_ERK1_MAPK1_ST	P49790	NUP153	P28482	MAPK1	S522	S522F	522	Missense	central	0	yes	14.700	0.000	EPSD;PhosphoSitePlus	COSMIC	8.102	Loss
CMGC_MAPK_ERK1_MAPK1_ST	P49790	NUP153	P28482	MAPK1	S529	P523S	523	Missense	distal	-6	no	14.304	14.278	EPSD;PhosphoSitePlus	COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P49790	NUP153	P28482	MAPK1	S529	T535I	535	Missense	distal	6	no	14.304	13.847	EPSD;PhosphoSitePlus	COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P49790	NUP153	P28482	MAPK1	S529	S522F	522	Missense	distal	-7	no	14.304	14.284	EPSD;PhosphoSitePlus	COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P49790	NUP153	P28482	MAPK1	T588	P589S	589	Missense	proximal	1	no	12.606	3.211	EPSD	COSMIC;GDSC	8.102	Loss
CMGC_MAPK_ERK1_MAPK1_ST	P49790	NUP153	P28482	MAPK1	S619	P620S	620	Missense	proximal	1	no	13.227	3.832	EPSD	COSMIC	8.102	Loss
CMGC_MAPK_ERK1_MAPK1_ST	P49790	NUP153	P28482	MAPK1	S633	A631S	631	Missense	proximal	-2	no	13.432	13.744	EPSD	COSMIC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P49790	NUP153	P28482	MAPK1	S687	T691I	691	Missense	distal	4	no	12.931	12.878	EPSD	COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P49790	NUP153	P28482	MAPK1	S687	Q694H	694	Missense	distal	7	no	12.931	13.035	EPSD	COSMIC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P49790	NUP153	P28482	MAPK1	S687	S687P	687	Missense	central	0	yes	12.931	0.000	EPSD	COSMIC	8.102	Loss
CMGC_MAPK_ERK1_MAPK1_ST	P49790	NUP153	P28482	MAPK1	T747	V743A	743	Missense	distal	-4	no	12.493	12.554	EPSD	COSMIC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P49790	NUP153	P28482	MAPK1	S902	S895L	895	Missense	distal	-7	no	9.137	9.129	EPSD	COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P49790	NUP153	P28482	MAPK1	S902	S902Y	902	Missense	central	0	yes	9.137	0.000	EPSD	COSMIC	8.102	Loss
CMGC_MAPK_ERK1_MAPK1_ST	P49790	NUP153	P28482	MAPK1	S902	K904I	904	Missense	proximal	2	no	9.137	9.034	EPSD	COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P49790	NUP153	P28482	MAPK1	S902	S900Y	900	Missense	proximal	-2	no	9.137	9.854	EPSD	COSMIC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P49790	NUP153	P28482	MAPK1	T996	V1002A	1002	Missense	distal	6	no	11.873	11.791	EPSD	COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P49790	NUP153	P28482	MAPK1	T996	T996I	996	Missense	central	0	yes	11.873	0.000	EPSD	COSMIC	8.102	Loss
CMGC_MAPK_ERK1_MAPK1_ST	P49790	NUP153	P28482	MAPK1	S1017	S1018F	1018	Missense	proximal	1	no	7.672	10.497	EPSD	COSMIC	8.102	Gain
CMGC_MAPK_ERK1_MAPK1_ST	P49790	NUP153	P28482	MAPK1	T1032	A1036P	1036	Missense	distal	4	no	12.934	13.038	EPSD	COSMIC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P49790	NUP153	P28482	MAPK1	T1032	P1035S	1035	Missense	distal	3	no	12.934	13.003	EPSD	COSMIC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P49790	NUP153	P28482	MAPK1	S1083	F1082L	1082	Missense	proximal	-1	no	8.099	8.129	EPSD	COSMIC;CCLE	8.102	Gain
CMGC_MAPK_ERK1_MAPK1_ST	P49790	NUP153	P28482	MAPK1	S1461	V1454M	1454	Missense	distal	-7	no	8.528	8.525	EPSD	COSMIC;GDSC;CCLE	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P49790	NUP153	P28482	MAPK1	S1461	I1467M	1467	Missense	distal	6	no	8.528	8.762	EPSD	COSMIC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q16690	DUSP5	P28482	MAPK1	S346	P347S	347	Missense	proximal	1	no	15.013	5.619	EPSD;PhosphoSitePlus	COSMIC	8.102	Loss
CMGC_MAPK_ERK1_MAPK1_ST	O95863	SNAI1	P28482	MAPK1	S82	R84T	84	Missense	proximal	2	no	12.900	12.736	EPSD;PhosphoSitePlus	COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	O95863	SNAI1	P28482	MAPK1	S82	V85M	85	Missense	distal	3	no	12.900	12.927	EPSD;PhosphoSitePlus	COSMIC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	O95863	SNAI1	P28482	MAPK1	S104	P102S	102	Missense	proximal	-2	no	18.403	15.569	PhosphoSitePlus;EPSD	COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	O95863	SNAI1	P28482	MAPK1	S104	P105Q	105	Missense	proximal	1	no	18.403	9.910	PhosphoSitePlus;EPSD	COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	O95863	SNAI1	P28482	MAPK1	S107	P102S	102	Missense	distal	-5	no	18.336	18.410	EPSD	COSMIC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	O95863	SNAI1	P28482	MAPK1	S107	P105Q	105	Missense	proximal	-2	no	18.336	15.343	EPSD	COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	O95863	SNAI1	P28482	MAPK1	S112	P105Q	105	Missense	distal	-7	no	10.083	10.086	EPSD	COSMIC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	O95863	SNAI1	P28482	MAPK1	S175	C180F	180	Missense	distal	5	no	7.918	8.121	EPSD	COSMIC	8.102	Gain
CMGC_MAPK_ERK1_MAPK1_ST	P35568	IRS1	P28482	MAPK1	S3	G9D	9	Missense	distal	6	no	12.534	12.565	EPSD	COSMIC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P35568	IRS1	P28482	MAPK1	S7	S11L	11	Missense	distal	4	no	8.412	8.303	EPSD	COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P35568	IRS1	P28482	MAPK1	S7	G9D	9	Missense	proximal	2	no	8.412	8.378	EPSD	COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P35568	IRS1	P28482	MAPK1	S273	S274P	274	Missense	proximal	1	no	4.498	13.892	EPSD	COSMIC	8.102	Gain
CMGC_MAPK_ERK1_MAPK1_ST	P35568	IRS1	P28482	MAPK1	S281	V282I	282	Missense	proximal	1	no	8.330	8.053	EPSD	COSMIC	8.102	Loss
CMGC_MAPK_ERK1_MAPK1_ST	P35568	IRS1	P28482	MAPK1	S281	S274P	274	Missense	distal	-7	no	8.330	8.335	EPSD	COSMIC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P35568	IRS1	P28482	MAPK1	S295	R301C	301	Missense	distal	6	no	9.800	9.040	EPSD	COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P35568	IRS1	P28482	MAPK1	S295	Q296R	296	Missense	proximal	1	no	9.800	8.639	EPSD	COSMIC;GDSC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P35568	IRS1	P28482	MAPK1	S295	R302L	302	Missense	distal	7	no	9.800	10.085	EPSD	COSMIC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P35568	IRS1	P28482	MAPK1	S295	L289F	289	Missense	distal	-6	no	9.800	9.781	EPSD	COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P35568	IRS1	P28482	MAPK1	S295	P292S	292	Missense	distal	-3	no	9.800	9.623	EPSD	COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P35568	IRS1	P28482	MAPK1	S295	P294T	294	Missense	proximal	-1	no	9.800	9.758	EPSD	COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P35568	IRS1	P28482	MAPK1	S312	E306K	306	Missense	distal	-6	no	12.828	12.802	EPSD	COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P35568	IRS1	P28482	MAPK1	S312	A310T	310	Missense	proximal	-2	no	12.828	13.276	EPSD	COSMIC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P35568	IRS1	P28482	MAPK1	S312	P313L	313	Missense	proximal	1	no	12.828	4.019	EPSD	COSMIC;GDSC;CCLE	8.102	Loss
CMGC_MAPK_ERK1_MAPK1_ST	P35568	IRS1	P28482	MAPK1	S312	M316V	316	Missense	distal	4	no	12.828	12.917	EPSD	COSMIC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P35568	IRS1	P28482	MAPK1	S312	M316I	316	Missense	distal	4	no	12.828	12.850	EPSD	COSMIC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P35568	IRS1	P28482	MAPK1	S312	I308M	308	Missense	distal	-4	no	12.828	13.033	EPSD	COSMIC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P35568	IRS1	P28482	MAPK1	S312	A310V	310	Missense	proximal	-2	no	12.828	14.102	EPSD	COSMIC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P35568	IRS1	P28482	MAPK1	S323	R327L	327	Missense	distal	4	no	10.184	10.097	EPSD	COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P35568	IRS1	P28482	MAPK1	S323	R325H	325	Missense	proximal	2	no	10.184	9.940	EPSD	COSMIC;CCLE	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P35568	IRS1	P28482	MAPK1	S323	R327C	327	Missense	distal	4	no	10.184	9.924	EPSD	COSMIC;CCLE	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P35568	IRS1	P28482	MAPK1	S323	M316V	316	Missense	distal	-7	no	10.184	10.186	EPSD	COSMIC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P35568	IRS1	P28482	MAPK1	S323	M316I	316	Missense	distal	-7	no	10.184	10.173	EPSD	COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P35568	IRS1	P28482	MAPK1	S323	R325C	325	Missense	proximal	2	no	10.184	9.811	EPSD	COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P35568	IRS1	P28482	MAPK1	S323	F324L	324	Missense	proximal	1	no	10.184	7.943	EPSD	COSMIC	8.102	Loss
CMGC_MAPK_ERK1_MAPK1_ST	P35568	IRS1	P28482	MAPK1	S345	S341L	341	Missense	distal	-4	no	14.233	14.012	EPSD	COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P35568	IRS1	P28482	MAPK1	S345	N352D	352	Missense	distal	7	no	14.233	14.246	EPSD	COSMIC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P35568	IRS1	P28482	MAPK1	S345	P349L	349	Missense	distal	4	no	14.233	14.112	EPSD	COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P35568	IRS1	P28482	MAPK1	S345	P346S	346	Missense	proximal	1	no	14.233	4.838	EPSD	COSMIC	8.102	Loss
CMGC_MAPK_ERK1_MAPK1_ST	P35568	IRS1	P28482	MAPK1	S348	S341L	341	Missense	distal	-7	no	17.404	17.396	EPSD	COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P35568	IRS1	P28482	MAPK1	S348	N352D	352	Missense	distal	4	no	17.404	17.344	EPSD	COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P35568	IRS1	P28482	MAPK1	S348	P349L	349	Missense	proximal	1	no	17.404	8.594	EPSD	COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P35568	IRS1	P28482	MAPK1	S348	P346S	346	Missense	proximal	-2	no	17.404	14.569	EPSD	COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P35568	IRS1	P28482	MAPK1	T354	A356P	356	Missense	proximal	2	no	8.140	8.269	EPSD	COSMIC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P35568	IRS1	P28482	MAPK1	T354	R358Q	358	Missense	distal	4	no	8.140	8.065	EPSD	COSMIC	8.102	Loss
CMGC_MAPK_ERK1_MAPK1_ST	P35568	IRS1	P28482	MAPK1	T354	G361S	361	Missense	distal	7	no	8.140	8.071	EPSD	COSMIC	8.102	Loss
CMGC_MAPK_ERK1_MAPK1_ST	P35568	IRS1	P28482	MAPK1	T354	N352D	352	Missense	proximal	-2	no	8.140	7.658	EPSD	COSMIC	8.102	Loss
CMGC_MAPK_ERK1_MAPK1_ST	P35568	IRS1	P28482	MAPK1	T354	P349L	349	Missense	distal	-5	no	8.140	8.289	EPSD	COSMIC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P35568	IRS1	P28482	MAPK1	S362	L369F	369	Missense	distal	7	no	8.870	8.929	EPSD	COSMIC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P35568	IRS1	P28482	MAPK1	S362	A356P	356	Missense	distal	-6	no	8.870	8.909	EPSD	COSMIC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P35568	IRS1	P28482	MAPK1	S362	R364Q	364	Missense	proximal	2	no	8.870	8.578	EPSD	COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P35568	IRS1	P28482	MAPK1	S362	R358Q	358	Missense	distal	-4	no	8.870	8.767	EPSD	COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P35568	IRS1	P28482	MAPK1	S362	G361S	361	Missense	proximal	-1	no	8.870	8.881	EPSD	COSMIC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P35568	IRS1	P28482	MAPK1	S383	A379P	379	Missense	distal	-4	no	15.450	15.743	EPSD	COSMIC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P35568	IRS1	P28482	MAPK1	S383	S383L	383	Missense	central	0	yes	15.450	0.000	EPSD	COSMIC	8.102	Loss
CMGC_MAPK_ERK1_MAPK1_ST	P35568	IRS1	P28482	MAPK1	S383	R381L	381	Missense	proximal	-2	no	15.450	15.351	EPSD	COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P35568	IRS1	P28482	MAPK1	S383	S383W	383	Missense	central	0	yes	15.450	0.000	EPSD	COSMIC	8.102	Loss
CMGC_MAPK_ERK1_MAPK1_ST	P35568	IRS1	P28482	MAPK1	S383	P384S	384	Missense	proximal	1	no	15.450	6.055	EPSD	COSMIC	8.102	Loss
CMGC_MAPK_ERK1_MAPK1_ST	P35568	IRS1	P28482	MAPK1	S383	S385L	385	Missense	proximal	2	no	15.450	15.330	EPSD	COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P35568	IRS1	P28482	MAPK1	S388	S383L	383	Missense	distal	-5	no	13.356	13.430	EPSD	COSMIC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P35568	IRS1	P28482	MAPK1	S388	R381L	381	Missense	distal	-7	no	13.356	13.348	EPSD	COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P35568	IRS1	P28482	MAPK1	S388	S383W	383	Missense	distal	-5	no	13.356	13.605	EPSD	COSMIC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P35568	IRS1	P28482	MAPK1	S388	S395I	395	Missense	distal	7	no	13.356	13.903	EPSD	COSMIC;GDSC;CCLE	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P35568	IRS1	P28482	MAPK1	S388	P384S	384	Missense	distal	-4	no	13.356	13.272	EPSD	COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P35568	IRS1	P28482	MAPK1	S388	S385L	385	Missense	distal	-3	no	13.356	13.148	EPSD	COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P35568	IRS1	P28482	MAPK1	S419	S415L	415	Missense	distal	-4	no	12.815	12.595	EPSD	COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P35568	IRS1	P28482	MAPK1	S419	G418V	418	Missense	proximal	-1	no	12.815	12.844	EPSD	COSMIC;GDSC;CCLE	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P35568	IRS1	P28482	MAPK1	S419	D422N	422	Missense	distal	3	no	12.815	12.720	EPSD	COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P35568	IRS1	P28482	MAPK1	S419	G423C	423	Missense	distal	4	no	12.815	12.583	EPSD	COSMIC;GDSC;CCLE	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P35568	IRS1	P28482	MAPK1	S419	G424C	424	Missense	distal	5	no	12.815	12.435	EPSD	COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P35568	IRS1	P28482	MAPK1	S434	P435L	435	Missense	proximal	1	no	13.960	5.150	EPSD	COSMIC	8.102	Loss
CMGC_MAPK_ERK1_MAPK1_ST	P35568	IRS1	P28482	MAPK1	S434	R439Q	439	Missense	distal	5	no	13.960	13.790	EPSD	COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P35568	IRS1	P28482	MAPK1	S434	S441Y	441	Missense	distal	7	no	13.960	14.477	EPSD	COSMIC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P35568	IRS1	P28482	MAPK1	S434	S434G	434	Missense	central	0	yes	13.960	0.000	EPSD	COSMIC	8.102	Loss
CMGC_MAPK_ERK1_MAPK1_ST	P35568	IRS1	P28482	MAPK1	S434	S441F	441	Missense	distal	7	no	13.960	14.307	EPSD	COSMIC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P35568	IRS1	P28482	MAPK1	S434	P435F	435	Missense	proximal	1	no	13.960	7.390	EPSD	COSMIC	8.102	Loss
CMGC_MAPK_ERK1_MAPK1_ST	P35568	IRS1	P28482	MAPK1	T446	G451C	451	Missense	distal	5	no	13.754	13.374	EPSD	COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P35568	IRS1	P28482	MAPK1	T446	R439Q	439	Missense	distal	-7	no	13.754	13.762	EPSD	COSMIC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P35568	IRS1	P28482	MAPK1	T446	D448E	448	Missense	proximal	2	no	13.754	13.703	EPSD	COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P35568	IRS1	P28482	MAPK1	T446	S441Y	441	Missense	distal	-5	no	13.754	13.886	EPSD	COSMIC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P35568	IRS1	P28482	MAPK1	T446	T453I	453	Missense	distal	7	no	13.754	14.150	EPSD	COSMIC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P35568	IRS1	P28482	MAPK1	T446	S441F	441	Missense	distal	-5	no	13.754	13.843	EPSD	COSMIC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P35568	IRS1	P28482	MAPK1	T446	R443C	443	Missense	distal	-3	no	13.754	13.071	EPSD	COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P35568	IRS1	P28482	MAPK1	T446	P447L	447	Missense	proximal	1	no	13.754	4.945	EPSD	COSMIC	8.102	Loss
CMGC_MAPK_ERK1_MAPK1_ST	P35568	IRS1	P28482	MAPK1	T446	R443L	443	Missense	distal	-3	no	13.754	13.390	EPSD	COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P35568	IRS1	P28482	MAPK1	T446	S444I	444	Missense	proximal	-2	no	13.754	14.694	EPSD	COSMIC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P35568	IRS1	P28482	MAPK1	T446	S449P	449	Missense	distal	3	no	13.754	13.685	EPSD	COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P35568	IRS1	P28482	MAPK1	T453	G451C	451	Missense	proximal	-2	no	13.742	13.169	EPSD	COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P35568	IRS1	P28482	MAPK1	T453	E460K	460	Missense	distal	7	no	13.742	13.749	EPSD	COSMIC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P35568	IRS1	P28482	MAPK1	T453	G458A	458	Missense	distal	5	no	13.742	13.601	EPSD	COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P35568	IRS1	P28482	MAPK1	T453	D448E	448	Missense	distal	-5	no	13.742	13.697	EPSD	COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P35568	IRS1	P28482	MAPK1	T453	T453I	453	Missense	central	0	yes	13.742	0.000	EPSD	COSMIC	8.102	Loss
CMGC_MAPK_ERK1_MAPK1_ST	P35568	IRS1	P28482	MAPK1	T453	P447L	447	Missense	distal	-6	no	13.742	13.650	EPSD	COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P35568	IRS1	P28482	MAPK1	T453	S449P	449	Missense	distal	-4	no	13.742	13.825	EPSD	COSMIC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P35568	IRS1	P28482	MAPK1	T475	A478T	478	Missense	distal	3	no	8.501	8.485	EPSD	COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P35568	IRS1	P28482	MAPK1	T475	M468I	468	Missense	distal	-7	no	8.501	8.491	EPSD	COSMIC;GDSC;CCLE	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P35568	IRS1	P28482	MAPK1	T475	G481S	481	Missense	distal	6	no	8.501	8.578	EPSD	COSMIC;GDSC;CCLE	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P35568	IRS1	P28482	MAPK1	T475	K471N	471	Missense	distal	-4	no	8.501	8.469	EPSD	COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P35568	IRS1	P28482	MAPK1	T475	G472W	472	Missense	distal	-3	no	8.501	7.972	EPSD	COSMIC	8.102	Loss
CMGC_MAPK_ERK1_MAPK1_ST	P35568	IRS1	P28482	MAPK1	T475	G472E	472	Missense	distal	-3	no	8.501	8.510	EPSD	COSMIC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P35568	IRS1	P28482	MAPK1	T475	G470V	470	Missense	distal	-5	no	8.501	8.529	EPSD	COSMIC;GDSC;CCLE	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P35568	IRS1	P28482	MAPK1	T495	T495A	495	Missense	central	0	yes	15.028	0.000	EPSD	COSMIC	8.102	Loss
CMGC_MAPK_ERK1_MAPK1_ST	P35568	IRS1	P28482	MAPK1	T495	G489D	489	Missense	distal	-6	no	15.028	15.094	EPSD	COSMIC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P35568	IRS1	P28482	MAPK1	T495	G497E	497	Missense	proximal	2	no	15.028	14.942	EPSD	COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P35568	IRS1	P28482	MAPK1	T495	H492Y	492	Missense	distal	-3	no	15.028	14.932	EPSD	COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P35568	IRS1	P28482	MAPK1	S503	G497E	497	Missense	distal	-6	no	11.520	11.574	EPSD	COSMIC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P35568	IRS1	P28482	MAPK1	S513	R520L	520	Missense	distal	7	no	7.995	8.280	EPSD	COSMIC	8.102	Gain
CMGC_MAPK_ERK1_MAPK1_ST	P35568	IRS1	P28482	MAPK1	S531	T530A	530	Missense	proximal	-1	no	13.822	13.827	EPSD	COSMIC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P35568	IRS1	P28482	MAPK1	S531	T533I	533	Missense	proximal	2	no	13.822	13.702	EPSD	COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P35568	IRS1	P28482	MAPK1	S531	H536N	536	Missense	distal	5	no	13.822	13.894	EPSD	COSMIC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P35568	IRS1	P28482	MAPK1	S531	H526Y	526	Missense	distal	-5	no	13.822	13.903	EPSD	COSMIC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P35568	IRS1	P28482	MAPK1	S531	G529D	529	Missense	proximal	-2	no	13.822	13.714	EPSD	COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P35568	IRS1	P28482	MAPK1	S531	T535A	535	Missense	distal	4	no	13.822	13.842	EPSD	COSMIC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P35568	IRS1	P28482	MAPK1	S531	Q537R	537	Missense	distal	6	no	13.822	14.002	EPSD	COSMIC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P35568	IRS1	P28482	MAPK1	S616	V622M	622	Missense	distal	6	no	16.452	16.234	EPSD	COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P35568	IRS1	P28482	MAPK1	S616	P614A	614	Missense	proximal	-2	no	16.452	13.305	EPSD	COSMIC;CCLE	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P35568	IRS1	P28482	MAPK1	S636	V640I	640	Missense	distal	4	no	15.895	15.828	PhosphoSitePlus;EPSD	COSMIC;GDSC;CCLE	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P35568	IRS1	P28482	MAPK1	S636	A642T	642	Missense	distal	6	no	15.895	15.981	PhosphoSitePlus;EPSD	COSMIC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P35568	IRS1	P28482	MAPK1	S636	G630E	630	Missense	distal	-6	no	15.895	15.949	PhosphoSitePlus;EPSD	COSMIC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P35568	IRS1	P28482	MAPK1	S639	V640I	640	Missense	proximal	1	no	8.312	8.034	EPSD;PhosphoSitePlus	COSMIC;GDSC;CCLE	8.102	Loss
CMGC_MAPK_ERK1_MAPK1_ST	P35568	IRS1	P28482	MAPK1	S639	A642T	642	Missense	distal	3	no	8.312	8.295	EPSD;PhosphoSitePlus	COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P35568	IRS1	P28482	MAPK1	S666	G661D	661	Missense	distal	-5	no	10.492	10.495	EPSD	COSMIC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P35568	IRS1	P28482	MAPK1	S666	G669S	669	Missense	distal	3	no	10.492	10.478	EPSD	COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P35568	IRS1	P28482	MAPK1	S666	M664I	664	Missense	proximal	-2	no	10.492	12.612	EPSD	COSMIC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P35568	IRS1	P28482	MAPK1	S672	G677D	677	Missense	distal	5	no	13.704	13.748	EPSD	COSMIC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P35568	IRS1	P28482	MAPK1	S672	G669S	669	Missense	distal	-3	no	13.704	13.716	EPSD	COSMIC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P35568	IRS1	P28482	MAPK1	S672	G677V	677	Missense	distal	5	no	13.704	13.581	EPSD	COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P35568	IRS1	P28482	MAPK1	S672	P679T	679	Missense	distal	7	no	13.704	13.867	EPSD	COSMIC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P35568	IRS1	P28482	MAPK1	S672	P679L	679	Missense	distal	7	no	13.704	14.003	EPSD	COSMIC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P35568	IRS1	P28482	MAPK1	S736	D731G	731	Missense	distal	-5	no	13.268	13.265	EPSD	COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P35568	IRS1	P28482	MAPK1	S736	V738G	738	Missense	proximal	2	no	13.268	13.340	EPSD	COSMIC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P35568	IRS1	P28482	MAPK1	S736	G739E	739	Missense	distal	3	no	13.268	13.175	EPSD	COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P35568	IRS1	P28482	MAPK1	S736	N734I	734	Missense	proximal	-2	no	13.268	14.193	EPSD	COSMIC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P35568	IRS1	P28482	MAPK1	S736	N734K	734	Missense	proximal	-2	no	13.268	13.668	EPSD	COSMIC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P35568	IRS1	P28482	MAPK1	S745	G739E	739	Missense	distal	-6	no	12.472	12.526	EPSD	COSMIC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P35568	IRS1	P28482	MAPK1	S892	L885Q	885	Missense	distal	-7	no	17.786	17.801	EPSD	COSMIC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P35568	IRS1	P28482	MAPK1	S918	P912L	912	Missense	distal	-6	no	13.024	12.932	EPSD	COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P35568	IRS1	P28482	MAPK1	S918	V913L	913	Missense	distal	-5	no	13.024	13.077	EPSD	COSMIC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P35568	IRS1	P28482	MAPK1	S918	H916Y	916	Missense	proximal	-2	no	13.024	13.662	EPSD	COSMIC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P35568	IRS1	P28482	MAPK1	S918	G911D	911	Missense	distal	-7	no	13.024	13.039	EPSD	COSMIC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P35568	IRS1	P28482	MAPK1	S1005	S1011I	1011	Missense	distal	6	no	12.461	11.794	EPSD	COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P35568	IRS1	P28482	MAPK1	S1005	R998C	998	Missense	distal	-7	no	12.461	12.429	EPSD	COSMIC;GDSC;CCLE	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P35568	IRS1	P28482	MAPK1	S1005	D1003H	1003	Missense	proximal	-2	no	12.461	13.008	EPSD	COSMIC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P35568	IRS1	P28482	MAPK1	S1005	P1009S	1009	Missense	distal	4	no	12.461	12.450	EPSD	COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P35568	IRS1	P28482	MAPK1	S1043	A1042T	1042	Missense	proximal	-1	no	12.161	12.156	EPSD	COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P35568	IRS1	P28482	MAPK1	S1043	A1050V	1050	Missense	distal	7	no	12.161	12.263	EPSD	COSMIC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P35568	IRS1	P28482	MAPK1	S1043	S1043F	1043	Missense	central	0	yes	12.161	0.000	EPSD	COSMIC	8.102	Loss
CMGC_MAPK_ERK1_MAPK1_ST	P35568	IRS1	P28482	MAPK1	S1078	P1079S	1079	Missense	proximal	1	no	12.871	3.476	EPSD	COSMIC	8.102	Loss
CMGC_MAPK_ERK1_MAPK1_ST	P35568	IRS1	P28482	MAPK1	S1078	S1078I	1078	Missense	central	0	yes	12.871	0.000	EPSD	COSMIC	8.102	Loss
CMGC_MAPK_ERK1_MAPK1_ST	P35568	IRS1	P28482	MAPK1	S1078	R1074L	1074	Missense	distal	-4	no	12.871	12.656	EPSD	COSMIC;CCLE	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P35568	IRS1	P28482	MAPK1	S1078	R1074Q	1074	Missense	distal	-4	no	12.871	12.768	EPSD	COSMIC;GDSC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P35568	IRS1	P28482	MAPK1	S1078	R1081C	1081	Missense	distal	3	no	12.871	12.998	EPSD	COSMIC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P35568	IRS1	P28482	MAPK1	T1107	E1102K	1102	Missense	distal	-5	no	12.379	12.356	EPSD	COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P35568	IRS1	P28482	MAPK1	S1143	R1140C	1140	Missense	distal	-3	no	8.732	8.048	EPSD	COSMIC;CCLE	8.102	Loss
CMGC_MAPK_ERK1_MAPK1_ST	P35568	IRS1	P28482	MAPK1	T1196	P1202L	1202	Missense	distal	6	no	14.980	14.573	EPSD	COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P35568	IRS1	P28482	MAPK1	S1213	R1220C	1220	Missense	distal	7	no	7.839	8.494	EPSD	COSMIC	8.102	Gain
CMGC_MAPK_ERK1_MAPK1_ST	P35568	IRS1	P28482	MAPK1	S1222	R1220C	1220	Missense	proximal	-2	no	8.279	6.332	EPSD	COSMIC	8.102	Loss
CMGC_MAPK_ERK1_MAPK1_ST	P35568	IRS1	P28482	MAPK1	S1222	D1225Y	1225	Missense	distal	3	no	8.279	8.320	EPSD	COSMIC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P35568	IRS1	P28482	MAPK1	S1222	A1228V	1228	Missense	distal	6	no	8.279	8.361	EPSD	COSMIC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P35568	IRS1	P28482	MAPK1	S1222	E1224Q	1224	Missense	proximal	2	no	8.279	8.169	EPSD	COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P35568	IRS1	P28482	MAPK1	S1222	L1226V	1226	Missense	distal	4	no	8.279	8.290	EPSD	COSMIC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P35568	IRS1	P28482	MAPK1	S1223	R1220C	1220	Missense	distal	-3	no	8.399	7.715	EPSD	COSMIC	8.102	Loss
CMGC_MAPK_ERK1_MAPK1_ST	P35568	IRS1	P28482	MAPK1	S1223	D1225Y	1225	Missense	proximal	2	no	8.399	8.219	EPSD	COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P35568	IRS1	P28482	MAPK1	S1223	A1228V	1228	Missense	distal	5	no	8.399	8.416	EPSD	COSMIC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P35568	IRS1	P28482	MAPK1	S1223	E1224Q	1224	Missense	proximal	1	no	8.399	8.676	EPSD	COSMIC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P35568	IRS1	P28482	MAPK1	S1223	L1226V	1226	Missense	distal	3	no	8.399	8.367	EPSD	COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P35568	IRS1	P28482	MAPK1	S1227	R1220C	1220	Missense	distal	-7	no	9.189	9.157	EPSD	COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P35568	IRS1	P28482	MAPK1	S1227	D1225Y	1225	Missense	proximal	-2	no	9.189	10.373	EPSD	COSMIC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P35568	IRS1	P28482	MAPK1	S1227	A1228V	1228	Missense	proximal	1	no	9.189	7.278	EPSD	COSMIC	8.102	Loss
CMGC_MAPK_ERK1_MAPK1_ST	P35568	IRS1	P28482	MAPK1	S1227	E1224Q	1224	Missense	distal	-3	no	9.189	9.072	EPSD	COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P35568	IRS1	P28482	MAPK1	S1227	L1226V	1226	Missense	proximal	-1	no	9.189	9.222	EPSD	COSMIC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	O00213	APBB1	P28482	MAPK1	S205	S203I	203	Missense	proximal	-2	no	7.518	8.458	EPSD	COSMIC	8.102	Gain
CMGC_MAPK_ERK1_MAPK1_ST	O00213	APBB1	P28482	MAPK1	S287	P283L	283	Missense	distal	-4	no	17.229	16.925	EPSD;PhosphoSitePlus	COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	O00213	APBB1	P28482	MAPK1	S287	P288T	288	Missense	proximal	1	no	17.229	8.730	EPSD;PhosphoSitePlus	COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	O00213	APBB1	P28482	MAPK1	S287	S293I	293	Missense	distal	6	no	17.229	16.562	EPSD;PhosphoSitePlus	COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	O00213	APBB1	P28482	MAPK1	S287	R285P	285	Missense	proximal	-2	no	17.229	19.048	EPSD;PhosphoSitePlus	COSMIC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	O00213	APBB1	P28482	MAPK1	T579	H582R	582	Missense	distal	3	no	13.507	13.465	EPSD	COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	O00213	APBB1	P28482	MAPK1	T579	R575H	575	Missense	distal	-4	no	13.507	13.356	EPSD	COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	O00213	APBB1	P28482	MAPK1	T579	A586V	586	Missense	distal	7	no	13.507	13.609	EPSD	COSMIC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	O00213	APBB1	P28482	MAPK1	T709	K703T	703	Missense	distal	-6	no	12.960	12.925	PhosphoSitePlus;EPSD	COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	O00213	APBB1	P28482	MAPK1	T709	L705M	705	Missense	distal	-4	no	12.960	12.798	PhosphoSitePlus;EPSD	COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P49023	PXN	P28482	MAPK1	S26	P22L	22	Missense	distal	-4	no	9.197	8.893	EPSD	COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P49023	PXN	P28482	MAPK1	S26	P22H	22	Missense	distal	-4	no	9.197	8.956	EPSD	COSMIC;GDSC;CCLE	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P49023	PXN	P28482	MAPK1	S26	P30L	30	Missense	distal	4	no	9.197	9.077	EPSD	COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P49023	PXN	P28482	MAPK1	T29	P22L	22	Missense	distal	-7	no	15.492	15.480	EPSD	COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P49023	PXN	P28482	MAPK1	T29	P22H	22	Missense	distal	-7	no	15.492	15.476	EPSD	COSMIC;GDSC;CCLE	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P49023	PXN	P28482	MAPK1	T29	P30L	30	Missense	proximal	1	no	15.492	6.682	EPSD	COSMIC	8.102	Loss
CMGC_MAPK_ERK1_MAPK1_ST	P49023	PXN	P28482	MAPK1	S32	P30L	30	Missense	proximal	-2	no	10.334	8.417	EPSD	COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P49023	PXN	P28482	MAPK1	S85	S83N	83	Missense	proximal	-2	no	13.327	13.342	EPSD	COSMIC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P49023	PXN	P28482	MAPK1	S106	P107L	107	Missense	proximal	1	no	14.716	5.907	EPSD	COSMIC;GDSC	8.102	Loss
CMGC_MAPK_ERK1_MAPK1_ST	P49023	PXN	P28482	MAPK1	S106	P107Q	107	Missense	proximal	1	no	14.716	6.223	EPSD	COSMIC	8.102	Loss
CMGC_MAPK_ERK1_MAPK1_ST	P49023	PXN	P28482	MAPK1	S119	F120S	120	Missense	proximal	1	no	9.007	6.182	EPSD	COSMIC	8.102	Loss
CMGC_MAPK_ERK1_MAPK1_ST	P49023	PXN	P28482	MAPK1	S119	S126P	126	Missense	distal	7	no	9.007	8.996	EPSD	COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P49023	PXN	P28482	MAPK1	S130	V133I	133	Missense	distal	3	no	14.828	14.899	EPSD;PhosphoSitePlus	COSMIC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P49023	PXN	P28482	MAPK1	S130	A127T	127	Missense	distal	-3	no	14.828	14.986	EPSD;PhosphoSitePlus	COSMIC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P49023	PXN	P28482	MAPK1	S130	T136M	136	Missense	distal	6	no	14.828	14.606	EPSD;PhosphoSitePlus	COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P49023	PXN	P28482	MAPK1	S130	S126P	126	Missense	distal	-4	no	14.828	14.912	EPSD;PhosphoSitePlus	COSMIC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P49023	PXN	P28482	MAPK1	S170	D165Y	165	Missense	distal	-5	no	15.431	15.566	EPSD	COSMIC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P49023	PXN	P28482	MAPK1	S170	G175W	175	Missense	distal	5	no	15.431	14.953	EPSD	COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P49023	PXN	P28482	MAPK1	S170	P163L	163	Missense	distal	-7	no	15.431	15.419	EPSD	COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P49023	PXN	P28482	MAPK1	S170	P172L	172	Missense	proximal	2	no	15.431	15.283	EPSD	COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P49023	PXN	P28482	MAPK1	S170	P171S	171	Missense	proximal	1	no	15.431	6.036	EPSD	COSMIC	8.102	Loss
CMGC_MAPK_ERK1_MAPK1_ST	P49023	PXN	P28482	MAPK1	S170	N168I	168	Missense	proximal	-2	no	15.431	16.356	EPSD	COSMIC;GDSC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P49023	PXN	P28482	MAPK1	S178	G175W	175	Missense	distal	-3	no	15.145	14.615	EPSD	COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P49023	PXN	P28482	MAPK1	S178	P172L	172	Missense	distal	-6	no	15.145	15.053	EPSD	COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P49023	PXN	P28482	MAPK1	S178	P171S	171	Missense	distal	-7	no	15.145	15.140	EPSD	COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P49023	PXN	P28482	MAPK1	S230	P231L	231	Missense	proximal	1	no	11.912	3.102	EPSD	COSMIC;CCLE	8.102	Loss
CMGC_MAPK_ERK1_MAPK1_ST	P49023	PXN	P28482	MAPK1	S230	P229L	229	Missense	proximal	-1	no	11.912	11.852	EPSD	COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P49023	PXN	P28482	MAPK1	S244	E241D	241	Missense	distal	-3	no	10.500	10.551	EPSD	COSMIC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P49023	PXN	P28482	MAPK1	S303	P304L	304	Missense	proximal	1	no	15.302	6.493	EPSD	COSMIC	8.102	Loss
CMGC_MAPK_ERK1_MAPK1_ST	P49023	PXN	P28482	MAPK1	S303	P304R	304	Missense	proximal	1	no	15.302	5.648	EPSD	COSMIC	8.102	Loss
CMGC_MAPK_ERK1_MAPK1_ST	P49023	PXN	P28482	MAPK1	S303	G300R	300	Missense	distal	-3	no	15.302	15.471	EPSD	COSMIC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P49023	PXN	P28482	MAPK1	S303	E309K	309	Missense	distal	6	no	15.302	15.326	EPSD	COSMIC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P49023	PXN	P28482	MAPK1	S303	D298Y	298	Missense	distal	-5	no	15.302	15.438	EPSD	COSMIC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P49023	PXN	P28482	MAPK1	S303	S303R	303	Missense	central	0	yes	15.302	0.000	EPSD	COSMIC	8.102	Loss
CMGC_MAPK_ERK1_MAPK1_ST	P49023	PXN	P28482	MAPK1	S303	G306R	306	Missense	distal	3	no	15.302	15.265	EPSD	COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P49023	PXN	P28482	MAPK1	S303	R301Q	301	Missense	proximal	-2	no	15.302	14.127	EPSD	COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P49023	PXN	P28482	MAPK1	S303	G299S	299	Missense	distal	-4	no	15.302	15.569	EPSD	COSMIC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P49023	PXN	P28482	MAPK1	S322	S322A	322	Missense	central	0	yes	11.412	0.000	EPSD	COSMIC	8.102	Loss
CMGC_MAPK_ERK1_MAPK1_ST	P49023	PXN	P28482	MAPK1	S340	L338P	338	Missense	proximal	-2	no	6.381	8.298	EPSD	COSMIC	8.102	Gain
CMGC_MAPK_ERK1_MAPK1_ST	P49023	PXN	P28482	MAPK1	S414	K407E	407	Missense	distal	-7	no	13.548	13.555	EPSD	COSMIC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P49023	PXN	P28482	MAPK1	S414	R416H	416	Missense	proximal	2	no	13.548	13.305	EPSD	COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P49023	PXN	P28482	MAPK1	S414	F413L	413	Missense	proximal	-1	no	13.548	13.578	EPSD	COSMIC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P14618	PKM	P28482	MAPK1	T15	A20T	20	Missense	distal	5	no	8.640	8.726	EPSD	COSMIC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P14618	PKM	P28482	MAPK1	T15	A11V	11	Missense	distal	-4	no	8.640	8.579	EPSD	COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P14618	PKM	P28482	MAPK1	T15	G9R	9	Missense	distal	-6	no	8.640	8.691	EPSD	COSMIC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P14618	PKM	P28482	MAPK1	T15	Q14H	14	Missense	proximal	-1	no	8.640	8.638	EPSD	COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P14618	PKM	P28482	MAPK1	S37	R32L	32	Missense	distal	-5	no	14.625	14.726	PhosphoSitePlus	COSMIC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P14618	PKM	P28482	MAPK1	T80	H81P	81	Missense	proximal	1	no	6.561	14.385	EPSD	COSMIC	8.102	Gain
CMGC_MAPK_ERK1_MAPK1_ST	P14618	PKM	P28482	MAPK1	S406	D407H	407	Missense	proximal	1	no	7.375	8.247	EPSD	COSMIC	8.102	Gain
CMGC_MAPK_ERK1_MAPK1_ST	P14618	PKM	P28482	MAPK1	S420	G415R	415	Missense	distal	-5	no	12.118	12.098	EPSD	COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P14618	PKM	P28482	MAPK1	S420	E418D	418	Missense	proximal	-2	no	12.118	11.196	EPSD	COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P14618	PKM	P28482	MAPK1	S420	S420F	420	Missense	central	0	yes	12.118	0.000	EPSD	COSMIC	8.102	Loss
CMGC_MAPK_ERK1_MAPK1_ST	P14618	PKM	P28482	MAPK1	S420	V414M	414	Missense	distal	-6	no	12.118	12.120	EPSD	COSMIC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P14618	PKM	P28482	MAPK1	S420	G415D	415	Missense	distal	-5	no	12.118	12.120	EPSD	COSMIC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P14618	PKM	P28482	MAPK1	S420	A413T	413	Missense	distal	-7	no	12.118	12.103	EPSD	COSMIC;GDSC;CCLE	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P14618	PKM	P28482	MAPK1	S420	A427V	427	Missense	distal	7	no	12.118	12.220	EPSD	COSMIC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P14618	PKM	P28482	MAPK1	S519	R526C	526	Missense	distal	7	no	7.654	8.310	EPSD	COSMIC	8.102	Gain
CMGC_MAPK_ERK1_MAPK1_ST	Q15418	RPS6KA1	P28482	MAPK1	S221	E216K	216	Missense	distal	-5	no	9.833	9.811	EPSD	COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q15418	RPS6KA1	P28482	MAPK1	S221	H215R	215	Missense	distal	-6	no	9.833	9.916	EPSD	COSMIC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q15418	RPS6KA1	P28482	MAPK1	S221	G224R	224	Missense	distal	3	no	9.833	9.796	EPSD	COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q15418	RPS6KA1	P28482	MAPK1	S221	H215P	215	Missense	distal	-6	no	9.833	9.908	EPSD	COSMIC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q15418	RPS6KA1	P28482	MAPK1	S221	S221A	221	Missense	central	0	yes	9.833	0.000	EPSD	COSMIC	8.102	Loss
CMGC_MAPK_ERK1_MAPK1_ST	Q15418	RPS6KA1	P28482	MAPK1	S307	G308D	308	Missense	proximal	1	no	7.046	8.415	EPSD	COSMIC	8.102	Gain
CMGC_MAPK_ERK1_MAPK1_ST	Q15418	RPS6KA1	P28482	MAPK1	T356	S357F	357	Missense	proximal	1	no	6.246	9.071	EPSD	COSMIC	8.102	Gain
CMGC_MAPK_ERK1_MAPK1_ST	Q15418	RPS6KA1	P28482	MAPK1	T359	K361Q	361	Missense	proximal	2	no	14.152	14.041	EPSD	COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q15418	RPS6KA1	P28482	MAPK1	T359	R358S	358	Missense	proximal	-1	no	14.152	14.128	EPSD	COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q15418	RPS6KA1	P28482	MAPK1	T359	I366T	366	Missense	distal	7	no	14.152	13.756	EPSD	COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q15418	RPS6KA1	P28482	MAPK1	T359	S357F	357	Missense	proximal	-2	no	14.152	14.345	EPSD	COSMIC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q15418	RPS6KA1	P28482	MAPK1	T359	R358H	358	Missense	proximal	-1	no	14.152	14.128	EPSD	COSMIC;CCLE	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q15418	RPS6KA1	P28482	MAPK1	S363	S369T	369	Missense	distal	6	no	15.594	15.384	EPSD	COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q15418	RPS6KA1	P28482	MAPK1	S363	K361Q	361	Missense	proximal	-2	no	15.594	15.020	EPSD	COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q15418	RPS6KA1	P28482	MAPK1	S363	R358S	358	Missense	distal	-5	no	15.594	15.621	EPSD	COSMIC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q15418	RPS6KA1	P28482	MAPK1	S363	I366T	366	Missense	distal	3	no	15.594	15.529	EPSD	COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q15418	RPS6KA1	P28482	MAPK1	S363	S357F	357	Missense	distal	-6	no	15.594	15.510	EPSD	COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q15418	RPS6KA1	P28482	MAPK1	S363	P368L	368	Missense	distal	5	no	15.594	15.381	EPSD	COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q15418	RPS6KA1	P28482	MAPK1	S363	P367R	367	Missense	distal	4	no	15.594	15.561	EPSD	COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q15418	RPS6KA1	P28482	MAPK1	S363	R358H	358	Missense	distal	-5	no	15.594	15.672	EPSD	COSMIC;CCLE	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q15418	RPS6KA1	P28482	MAPK1	S363	S369N	369	Missense	distal	6	no	15.594	15.498	EPSD	COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q15418	RPS6KA1	P28482	MAPK1	S369	I366T	366	Missense	distal	-3	no	8.918	9.150	EPSD	COSMIC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q15418	RPS6KA1	P28482	MAPK1	S369	P368L	368	Missense	proximal	-1	no	8.918	8.858	EPSD	COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q15418	RPS6KA1	P28482	MAPK1	S369	P367R	367	Missense	proximal	-2	no	8.918	7.099	EPSD	COSMIC	8.102	Loss
CMGC_MAPK_ERK1_MAPK1_ST	Q15418	RPS6KA1	P28482	MAPK1	S369	S369N	369	Missense	central	0	yes	8.918	0.000	EPSD	COSMIC	8.102	Loss
CMGC_MAPK_ERK1_MAPK1_ST	Q15418	RPS6KA1	P28482	MAPK1	S380	G385S	385	Missense	distal	5	no	8.417	8.436	EPSD	COSMIC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q15418	RPS6KA1	P28482	MAPK1	S513	H517N	517	Missense	distal	4	no	8.002	8.129	EPSD	COSMIC	8.102	Gain
CMGC_MAPK_ERK1_MAPK1_ST	Q15418	RPS6KA1	P28482	MAPK1	T573	A566V	566	Missense	distal	-7	no	15.121	15.104	PhosphoSitePlus	COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q15418	RPS6KA1	P28482	MAPK1	T573	G569E	569	Missense	distal	-4	no	15.121	15.442	PhosphoSitePlus	COSMIC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q15418	RPS6KA1	P28482	MAPK1	T573	T577A	577	Missense	distal	4	no	15.121	15.140	PhosphoSitePlus	COSMIC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q15418	RPS6KA1	P28482	MAPK1	T621	R628W	628	Missense	distal	7	no	10.629	11.601	EPSD	COSMIC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q15418	RPS6KA1	P28482	MAPK1	T621	T621A	621	Missense	central	0	yes	10.629	0.000	EPSD	COSMIC	8.102	Loss
CMGC_MAPK_ERK1_MAPK1_ST	Q15418	RPS6KA1	P28482	MAPK1	T621	P622L	622	Missense	proximal	1	no	10.629	1.819	EPSD	COSMIC	8.102	Loss
CMGC_MAPK_ERK1_MAPK1_ST	Q15418	RPS6KA1	P28482	MAPK1	T621	G617S	617	Missense	distal	-4	no	10.629	10.895	EPSD	COSMIC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q15418	RPS6KA1	P28482	MAPK1	T635	L636P	636	Missense	proximal	1	no	3.829	12.639	EPSD	COSMIC	8.102	Gain
CMGC_MAPK_ERK1_MAPK1_ST	Q15418	RPS6KA1	P28482	MAPK1	S703	T701P	701	Missense	proximal	-2	no	7.312	10.012	EPSD	COSMIC	8.102	Gain
CMGC_MAPK_ERK1_MAPK1_ST	Q15418	RPS6KA1	P28482	MAPK1	S707	S708P	708	Missense	proximal	1	no	6.141	15.536	EPSD	COSMIC	8.102	Gain
CMGC_MAPK_ERK1_MAPK1_ST	Q15418	RPS6KA1	P28482	MAPK1	S707	S708F	708	Missense	proximal	1	no	6.141	8.966	EPSD	COSMIC	8.102	Gain
CMGC_MAPK_ERK1_MAPK1_ST	Q15418	RPS6KA1	P28482	MAPK1	T711	S708P	708	Missense	distal	-3	no	13.769	13.946	EPSD	COSMIC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q15418	RPS6KA1	P28482	MAPK1	T711	S708F	708	Missense	distal	-3	no	13.769	13.537	EPSD	COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q15418	RPS6KA1	P28482	MAPK1	T711	P712S	712	Missense	proximal	1	no	13.769	4.374	EPSD	COSMIC	8.102	Loss
CMGC_MAPK_ERK1_MAPK1_ST	Q15418	RPS6KA1	P28482	MAPK1	T711	A704T	704	Missense	distal	-7	no	13.769	13.755	EPSD	COSMIC;CCLE	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q15418	RPS6KA1	P28482	MAPK1	T711	T711P	711	Missense	central	0	yes	13.769	0.000	EPSD	COSMIC	8.102	Loss
CMGC_MAPK_ERK1_MAPK1_ST	Q15418	RPS6KA1	P28482	MAPK1	S719	L722V	722	Missense	distal	3	no	9.032	9.000	EPSD	COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q15418	RPS6KA1	P28482	MAPK1	S719	P712S	712	Missense	distal	-7	no	9.032	9.028	EPSD	COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q15418	RPS6KA1	P28482	MAPK1	S719	R726Q	726	Missense	distal	7	no	9.032	9.147	EPSD	COSMIC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q15418	RPS6KA1	P28482	MAPK1	S719	R725W	725	Missense	distal	6	no	9.032	8.109	EPSD	COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q15418	RPS6KA1	P28482	MAPK1	S719	S719P	719	Missense	central	0	yes	9.032	0.000	EPSD	COSMIC	8.102	Loss
CMGC_MAPK_ERK1_MAPK1_ST	Q15418	RPS6KA1	P28482	MAPK1	S719	S720C	720	Missense	proximal	1	no	9.032	4.979	EPSD	COSMIC	8.102	Loss
CMGC_MAPK_ERK1_MAPK1_ST	Q15418	RPS6KA1	P28482	MAPK1	S732	R726Q	726	Missense	distal	-6	no	8.261	8.237	EPSD	COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q15418	RPS6KA1	P28482	MAPK1	S732	R725W	725	Missense	distal	-7	no	8.261	8.210	EPSD	COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q15418	RPS6KA1	P28482	MAPK1	T733	R726Q	726	Missense	distal	-7	no	8.973	8.981	EPSD	COSMIC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q09472	EP300	P28482	MAPK1	S12	E7K	7	Missense	distal	-5	no	10.311	10.289	EPSD	COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q09472	EP300	P28482	MAPK1	S12	P10R	10	Missense	proximal	-2	no	10.311	8.493	EPSD	COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q09472	EP300	P28482	MAPK1	S12	G9R	9	Missense	distal	-3	no	10.311	10.480	EPSD	COSMIC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q09472	EP300	P28482	MAPK1	S12	A13T	13	Missense	proximal	1	no	10.311	9.443	EPSD	COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q09472	EP300	P28482	MAPK1	S12	A13V	13	Missense	proximal	1	no	10.311	8.401	EPSD	COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q09472	EP300	P28482	MAPK1	S12	V5L	5	Missense	distal	-7	no	10.311	10.318	EPSD	COSMIC;CCLE	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q09472	EP300	P28482	MAPK1	S12	S12A	12	Missense	central	0	yes	10.311	0.000	EPSD	COSMIC	8.102	Loss
CMGC_MAPK_ERK1_MAPK1_ST	Q09472	EP300	P28482	MAPK1	S20	A13T	13	Missense	distal	-7	no	17.537	17.522	EPSD	COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q09472	EP300	P28482	MAPK1	S20	P21L	21	Missense	proximal	1	no	17.537	8.727	EPSD	COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q09472	EP300	P28482	MAPK1	S20	A13V	13	Missense	distal	-7	no	17.537	17.520	EPSD	COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q09472	EP300	P28482	MAPK1	S24	G30V	30	Missense	distal	6	no	9.677	9.539	EPSD	COSMIC;CCLE	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q09472	EP300	P28482	MAPK1	S24	G30D	30	Missense	distal	6	no	9.677	9.709	EPSD	COSMIC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q09472	EP300	P28482	MAPK1	S24	P21L	21	Missense	distal	-3	no	9.677	9.293	EPSD	COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q09472	EP300	P28482	MAPK1	S26	G30V	30	Missense	distal	4	no	8.548	8.498	EPSD	COSMIC;CCLE	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q09472	EP300	P28482	MAPK1	S26	G30D	30	Missense	distal	4	no	8.548	8.500	EPSD	COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q09472	EP300	P28482	MAPK1	S26	P21L	21	Missense	distal	-5	no	8.548	8.697	EPSD	COSMIC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q09472	EP300	P28482	MAPK1	S28	G30V	30	Missense	proximal	2	no	8.492	8.420	EPSD	COSMIC;CCLE	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q09472	EP300	P28482	MAPK1	S28	G30D	30	Missense	proximal	2	no	8.492	8.457	EPSD	COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q09472	EP300	P28482	MAPK1	S28	P21L	21	Missense	distal	-7	no	8.492	8.479	EPSD	COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q09472	EP300	P28482	MAPK1	S90	M95V	95	Missense	distal	5	no	13.019	13.081	EPSD	COSMIC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q09472	EP300	P28482	MAPK1	S90	S87Y	87	Missense	distal	-3	no	13.019	12.750	EPSD	COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q09472	EP300	P28482	MAPK1	S112	S112N	112	Missense	central	0	yes	13.300	0.000	EPSD	COSMIC	8.102	Loss
CMGC_MAPK_ERK1_MAPK1_ST	Q09472	EP300	P28482	MAPK1	S112	A108V	108	Missense	distal	-4	no	13.300	13.239	EPSD	COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q09472	EP300	P28482	MAPK1	S112	Q107H	107	Missense	distal	-5	no	13.300	13.299	EPSD	COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q09472	EP300	P28482	MAPK1	S227	E221G	221	Missense	distal	-6	no	13.811	13.757	EPSD	COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q09472	EP300	P28482	MAPK1	S227	G231E	231	Missense	distal	4	no	13.811	13.833	EPSD	COSMIC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q09472	EP300	P28482	MAPK1	S255	P252L	252	Missense	distal	-3	no	15.083	14.700	EPSD	COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q09472	EP300	P28482	MAPK1	S255	Y253C	253	Missense	proximal	-2	no	15.083	13.434	EPSD	COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q09472	EP300	P28482	MAPK1	S255	N248T	248	Missense	distal	-7	no	15.083	15.068	EPSD	COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q09472	EP300	P28482	MAPK1	S255	P250H	250	Missense	distal	-5	no	15.083	15.208	EPSD	COSMIC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q09472	EP300	P28482	MAPK1	S255	P252S	252	Missense	distal	-3	no	15.083	14.907	EPSD	COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q09472	EP300	P28482	MAPK1	S255	S255L	255	Missense	central	0	yes	15.083	0.000	EPSD	COSMIC	8.102	Loss
CMGC_MAPK_ERK1_MAPK1_ST	Q09472	EP300	P28482	MAPK1	S255	P256S	256	Missense	proximal	1	no	15.083	5.688	EPSD	COSMIC	8.102	Loss
CMGC_MAPK_ERK1_MAPK1_ST	Q09472	EP300	P28482	MAPK1	S255	P250S	250	Missense	distal	-5	no	15.083	15.158	EPSD	COSMIC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q09472	EP300	P28482	MAPK1	S255	N248H	248	Missense	distal	-7	no	15.083	15.069	EPSD	COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q09472	EP300	P28482	MAPK1	S285	D290N	290	Missense	distal	5	no	13.630	13.532	EPSD	COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q09472	EP300	P28482	MAPK1	S285	V279A	279	Missense	distal	-6	no	13.630	13.677	EPSD	COSMIC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q09472	EP300	P28482	MAPK1	T317	G314V	314	Missense	distal	-3	no	14.325	14.206	EPSD;PhosphoSitePlus	COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q09472	EP300	P28482	MAPK1	T317	P313S	313	Missense	distal	-4	no	14.325	14.241	EPSD;PhosphoSitePlus	COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q09472	EP300	P28482	MAPK1	S396	R397P	397	Missense	proximal	1	no	4.887	14.541	EPSD	COSMIC	8.102	Gain
CMGC_MAPK_ERK1_MAPK1_ST	Q09472	EP300	P28482	MAPK1	S499	P500S	500	Missense	proximal	1	no	12.989	3.594	EPSD	COSMIC	8.102	Loss
CMGC_MAPK_ERK1_MAPK1_ST	Q09472	EP300	P28482	MAPK1	S499	R504W	504	Missense	distal	5	no	12.989	12.461	EPSD	COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q09472	EP300	P28482	MAPK1	S831	L827P	827	Missense	distal	-4	no	12.213	12.517	EPSD	COSMIC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q09472	EP300	P28482	MAPK1	S831	R838S	838	Missense	distal	7	no	12.213	12.210	EPSD	COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q09472	EP300	P28482	MAPK1	S833	T839I	839	Missense	distal	6	no	13.457	13.000	EPSD	COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q09472	EP300	P28482	MAPK1	S833	L827P	827	Missense	distal	-6	no	13.457	13.549	EPSD	COSMIC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q09472	EP300	P28482	MAPK1	S833	R838S	838	Missense	distal	5	no	13.457	13.425	EPSD	COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q09472	EP300	P28482	MAPK1	T839	T845S	845	Missense	distal	6	no	14.395	14.606	EPSD	COSMIC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q09472	EP300	P28482	MAPK1	T839	P842S	842	Missense	distal	3	no	14.395	14.465	EPSD	COSMIC;CCLE	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q09472	EP300	P28482	MAPK1	T839	T839I	839	Missense	central	0	yes	14.395	0.000	EPSD	COSMIC	8.102	Loss
CMGC_MAPK_ERK1_MAPK1_ST	Q09472	EP300	P28482	MAPK1	T839	P846S	846	Missense	distal	7	no	14.395	14.406	EPSD	COSMIC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q09472	EP300	P28482	MAPK1	T839	P842L	842	Missense	distal	3	no	14.395	14.485	EPSD	COSMIC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q09472	EP300	P28482	MAPK1	T839	R838S	838	Missense	proximal	-1	no	14.395	14.372	EPSD	COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q09472	EP300	P28482	MAPK1	T841	T845S	845	Missense	distal	4	no	15.272	15.385	EPSD	COSMIC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q09472	EP300	P28482	MAPK1	T841	P842S	842	Missense	proximal	1	no	15.272	5.877	EPSD	COSMIC;CCLE	8.102	Loss
CMGC_MAPK_ERK1_MAPK1_ST	Q09472	EP300	P28482	MAPK1	T841	T839I	839	Missense	proximal	-2	no	15.272	16.077	EPSD	COSMIC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q09472	EP300	P28482	MAPK1	T841	P846S	846	Missense	distal	5	no	15.272	15.290	EPSD	COSMIC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q09472	EP300	P28482	MAPK1	T841	P842L	842	Missense	proximal	1	no	15.272	6.462	EPSD	COSMIC	8.102	Loss
CMGC_MAPK_ERK1_MAPK1_ST	Q09472	EP300	P28482	MAPK1	T841	R838S	838	Missense	distal	-3	no	15.272	15.115	EPSD	COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q09472	EP300	P28482	MAPK1	T845	P842S	842	Missense	distal	-3	no	14.243	14.066	EPSD	COSMIC;CCLE	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q09472	EP300	P28482	MAPK1	T845	T839I	839	Missense	distal	-6	no	14.243	14.165	EPSD	COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q09472	EP300	P28482	MAPK1	T845	P846S	846	Missense	proximal	1	no	14.243	4.848	EPSD	COSMIC	8.102	Loss
CMGC_MAPK_ERK1_MAPK1_ST	Q09472	EP300	P28482	MAPK1	T845	P847S	847	Missense	proximal	2	no	14.243	14.215	EPSD	COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q09472	EP300	P28482	MAPK1	T845	I849T	849	Missense	distal	4	no	14.243	14.296	EPSD	COSMIC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q09472	EP300	P28482	MAPK1	T845	P842L	842	Missense	distal	-3	no	14.243	13.859	EPSD	COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q09472	EP300	P28482	MAPK1	S848	I849T	849	Missense	proximal	1	no	7.085	8.405	EPSD	COSMIC	8.102	Gain
CMGC_MAPK_ERK1_MAPK1_ST	Q09472	EP300	P28482	MAPK1	T857	I859S	859	Missense	proximal	2	no	8.061	8.204	EPSD	COSMIC	8.102	Gain
CMGC_MAPK_ERK1_MAPK1_ST	Q09472	EP300	P28482	MAPK1	T865	A868V	868	Missense	distal	3	no	14.040	14.019	EPSD	COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q09472	EP300	P28482	MAPK1	T865	I859S	859	Missense	distal	-6	no	14.040	14.141	EPSD	COSMIC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q09472	EP300	P28482	MAPK1	T865	P870S	870	Missense	distal	5	no	14.040	14.058	EPSD	COSMIC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q09472	EP300	P28482	MAPK1	T865	P864S	864	Missense	proximal	-1	no	14.040	13.996	EPSD	COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q09472	EP300	P28482	MAPK1	T885	T890P	890	Missense	distal	5	no	15.433	15.489	EPSD	COSMIC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q09472	EP300	P28482	MAPK1	T885	P882R	882	Missense	distal	-3	no	15.433	15.413	EPSD	COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q09472	EP300	P28482	MAPK1	T885	T891P	891	Missense	distal	6	no	15.433	15.643	EPSD	COSMIC;CCLE	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q09472	EP300	P28482	MAPK1	T885	P882S	882	Missense	distal	-3	no	15.433	15.257	EPSD	COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q09472	EP300	P28482	MAPK1	T887	T890P	890	Missense	distal	3	no	12.313	12.251	EPSD	COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q09472	EP300	P28482	MAPK1	T887	P882R	882	Missense	distal	-5	no	12.313	12.360	EPSD	COSMIC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q09472	EP300	P28482	MAPK1	T887	P894S	894	Missense	distal	7	no	12.313	12.323	EPSD	COSMIC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q09472	EP300	P28482	MAPK1	T887	T891P	891	Missense	distal	4	no	12.313	12.436	EPSD	COSMIC;CCLE	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q09472	EP300	P28482	MAPK1	T887	P882S	882	Missense	distal	-5	no	12.313	12.387	EPSD	COSMIC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q09472	EP300	P28482	MAPK1	T890	T891P	891	Missense	proximal	1	no	7.957	16.456	EPSD	COSMIC;CCLE	8.102	Gain
CMGC_MAPK_ERK1_MAPK1_ST	Q09472	EP300	P28482	MAPK1	T938	P933S	933	Missense	distal	-5	no	15.126	15.200	EPSD;PhosphoSitePlus	COSMIC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q09472	EP300	P28482	MAPK1	S1038	S1037L	1037	Missense	proximal	-1	no	14.385	14.368	EPSD	COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q09472	EP300	P28482	MAPK1	S1038	G1042R	1042	Missense	distal	4	no	14.385	14.411	EPSD	COSMIC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q09472	EP300	P28482	MAPK1	T1135	S1136P	1136	Missense	proximal	1	no	3.332	12.727	EPSD	COSMIC	8.102	Gain
CMGC_MAPK_ERK1_MAPK1_ST	Q09472	EP300	P28482	MAPK1	S1220	Q1221H	1221	Missense	proximal	1	no	7.520	8.189	EPSD	COSMIC	8.102	Gain
CMGC_MAPK_ERK1_MAPK1_ST	Q09472	EP300	P28482	MAPK1	S1318	R1311K	1311	Missense	distal	-7	no	8.168	8.171	EPSD	COSMIC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q09472	EP300	P28482	MAPK1	S1318	H1315D	1315	Missense	distal	-3	no	8.168	8.389	EPSD	COSMIC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q09472	EP300	P28482	MAPK1	S1318	R1324K	1324	Missense	distal	6	no	8.168	8.332	EPSD	COSMIC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q09472	EP300	P28482	MAPK1	S1318	V1321I	1321	Missense	distal	3	no	8.168	8.238	EPSD	COSMIC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q09472	EP300	P28482	MAPK1	S1726	S1730Y	1730	Missense	distal	4	no	15.158	14.963	EPSD	COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q09472	EP300	P28482	MAPK1	S1726	S1730F	1730	Missense	distal	4	no	15.158	14.980	EPSD	COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q09472	EP300	P28482	MAPK1	S1726	R1732H	1732	Missense	distal	6	no	15.158	14.959	EPSD	COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q09472	EP300	P28482	MAPK1	S1849	G1842E	1842	Missense	distal	-7	no	13.372	13.395	EPSD	COSMIC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q09472	EP300	P28482	MAPK1	S1849	P1848S	1848	Missense	proximal	-1	no	13.372	13.329	EPSD	COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q09472	EP300	P28482	MAPK1	T1851	P1855S	1855	Missense	distal	4	no	12.194	12.183	EPSD	COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q09472	EP300	P28482	MAPK1	T1851	T1857P	1857	Missense	distal	6	no	12.194	12.404	EPSD	COSMIC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q09472	EP300	P28482	MAPK1	T1851	P1848S	1848	Missense	distal	-3	no	12.194	12.017	EPSD	COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q09472	EP300	P28482	MAPK1	T1854	P1855S	1855	Missense	proximal	1	no	15.410	6.015	EPSD	COSMIC	8.102	Loss
CMGC_MAPK_ERK1_MAPK1_ST	Q09472	EP300	P28482	MAPK1	T1854	T1857P	1857	Missense	distal	3	no	15.410	15.348	EPSD	COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q09472	EP300	P28482	MAPK1	T1854	G1860D	1860	Missense	distal	6	no	15.410	15.442	EPSD	COSMIC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q09472	EP300	P28482	MAPK1	T1854	P1848S	1848	Missense	distal	-6	no	15.410	15.384	EPSD	COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q09472	EP300	P28482	MAPK1	T1856	T1857P	1857	Missense	proximal	1	no	5.240	13.738	EPSD	COSMIC	8.102	Gain
CMGC_MAPK_ERK1_MAPK1_ST	Q09472	EP300	P28482	MAPK1	T1857	P1855S	1855	Missense	proximal	-2	no	17.476	14.642	EPSD	COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q09472	EP300	P28482	MAPK1	T1857	T1857P	1857	Missense	central	0	yes	17.476	0.000	EPSD	COSMIC	8.102	Loss
CMGC_MAPK_ERK1_MAPK1_ST	Q09472	EP300	P28482	MAPK1	T1857	G1860D	1860	Missense	distal	3	no	17.476	17.479	EPSD	COSMIC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q09472	EP300	P28482	MAPK1	T1857	Q1862P	1862	Missense	distal	5	no	17.476	17.597	EPSD	COSMIC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q09472	EP300	P28482	MAPK1	T1859	T1857P	1857	Missense	proximal	-2	no	5.419	8.118	EPSD	COSMIC	8.102	Gain
CMGC_MAPK_ERK1_MAPK1_ST	Q09472	EP300	P28482	MAPK1	T1864	Q1862P	1862	Missense	proximal	-2	no	5.818	8.811	EPSD	COSMIC	8.102	Gain
CMGC_MAPK_ERK1_MAPK1_ST	Q09472	EP300	P28482	MAPK1	T1865	P1869L	1869	Missense	distal	4	no	17.756	17.635	EPSD	COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q09472	EP300	P28482	MAPK1	T1865	P1866L	1866	Missense	proximal	1	no	17.756	8.946	EPSD	COSMIC;CCLE	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q09472	EP300	P28482	MAPK1	T1865	G1860D	1860	Missense	distal	-5	no	17.756	17.758	EPSD	COSMIC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q09472	EP300	P28482	MAPK1	T1865	P1863S	1863	Missense	proximal	-2	no	17.756	14.921	EPSD	COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q09472	EP300	P28482	MAPK1	T1865	Q1862P	1862	Missense	distal	-3	no	17.756	18.052	EPSD	COSMIC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q09472	EP300	P28482	MAPK1	T1865	Q1867K	1867	Missense	proximal	2	no	17.756	17.866	EPSD	COSMIC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q09472	EP300	P28482	MAPK1	T1906	P1907S	1907	Missense	proximal	1	no	11.793	2.398	EPSD	COSMIC	8.102	Loss
CMGC_MAPK_ERK1_MAPK1_ST	Q09472	EP300	P28482	MAPK1	T1906	T1906I	1906	Missense	central	0	yes	11.793	0.000	EPSD	COSMIC	8.102	Loss
CMGC_MAPK_ERK1_MAPK1_ST	Q09472	EP300	P28482	MAPK1	T1906	G1899D	1899	Missense	distal	-7	no	11.793	11.808	EPSD	COSMIC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q09472	EP300	P28482	MAPK1	T1909	P1907S	1907	Missense	proximal	-2	no	15.192	12.358	EPSD	COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q09472	EP300	P28482	MAPK1	T1909	T1906I	1906	Missense	distal	-3	no	15.192	14.961	EPSD	COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q09472	EP300	P28482	MAPK1	T1913	G1920R	1920	Missense	distal	7	no	8.774	8.709	EPSD	COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q09472	EP300	P28482	MAPK1	T1913	P1907S	1907	Missense	distal	-6	no	8.774	8.747	EPSD	COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q09472	EP300	P28482	MAPK1	T1913	T1906I	1906	Missense	distal	-7	no	8.774	8.759	EPSD	COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q09472	EP300	P28482	MAPK1	T1960	P1957A	1957	Missense	distal	-3	no	18.000	17.633	EPSD;PhosphoSitePlus	COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q09472	EP300	P28482	MAPK1	T1960	G1966S	1966	Missense	distal	6	no	18.000	18.077	EPSD;PhosphoSitePlus	COSMIC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q09472	EP300	P28482	MAPK1	T1960	P1964S	1964	Missense	distal	4	no	18.000	17.989	EPSD;PhosphoSitePlus	COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q09472	EP300	P28482	MAPK1	T1960	M1965I	1965	Missense	distal	5	no	18.000	17.887	EPSD;PhosphoSitePlus	COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q09472	EP300	P28482	MAPK1	T1960	M1965V	1965	Missense	distal	5	no	18.000	18.061	EPSD;PhosphoSitePlus	COSMIC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q09472	EP300	P28482	MAPK1	S2039	T2045S	2045	Missense	distal	6	no	12.392	12.602	EPSD	COSMIC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q09472	EP300	P28482	MAPK1	S2039	I2038M	2038	Missense	proximal	-1	no	12.392	12.408	EPSD	COSMIC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q09472	EP300	P28482	MAPK1	S2279	P2286S	2286	Missense	distal	7	no	16.736	16.746	EPSD;PhosphoSitePlus	COSMIC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q09472	EP300	P28482	MAPK1	S2279	P2277L	2277	Missense	proximal	-2	no	16.736	14.818	EPSD;PhosphoSitePlus	COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q09472	EP300	P28482	MAPK1	S2309	P2314T	2314	Missense	distal	5	no	12.769	12.714	EPSD	COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q09472	EP300	P28482	MAPK1	S2309	L2303F	2303	Missense	distal	-6	no	12.769	12.751	EPSD	COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q09472	EP300	P28482	MAPK1	S2309	Q2306H	2306	Missense	distal	-3	no	12.769	12.717	EPSD	COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q09472	EP300	P28482	MAPK1	S2309	P2312S	2312	Missense	distal	3	no	12.769	12.838	EPSD	COSMIC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q09472	EP300	P28482	MAPK1	S2315	P2314T	2314	Missense	proximal	-1	no	15.570	15.528	PhosphoSitePlus;EPSD	COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q09472	EP300	P28482	MAPK1	S2315	R2317W	2317	Missense	proximal	2	no	15.570	15.202	PhosphoSitePlus;EPSD	COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q09472	EP300	P28482	MAPK1	S2315	P2312S	2312	Missense	distal	-3	no	15.570	15.393	PhosphoSitePlus;EPSD	COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q09472	EP300	P28482	MAPK1	S2326	H2324T	2324	Missense	proximal	-2	no	12.494	12.549	EPSD	COSMIC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q09472	EP300	P28482	MAPK1	S2326	H2324Y	2324	Missense	proximal	-2	no	12.494	13.131	EPSD	COSMIC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q09472	EP300	P28482	MAPK1	S2328	H2324T	2324	Missense	distal	-4	no	15.428	15.356	EPSD	COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q09472	EP300	P28482	MAPK1	S2328	H2324Y	2324	Missense	distal	-4	no	15.428	14.997	EPSD	COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q09472	EP300	P28482	MAPK1	S2366	N2370I	2370	Missense	distal	4	no	13.450	13.322	EPSD;PhosphoSitePlus	COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q09472	EP300	P28482	MAPK1	S2366	M2372V	2372	Missense	distal	6	no	13.450	13.669	EPSD;PhosphoSitePlus	COSMIC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q09472	EP300	P28482	MAPK1	S2366	M2359R	2359	Missense	distal	-7	no	13.450	13.467	EPSD;PhosphoSitePlus	COSMIC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P38936	CDKN1A	P28482	MAPK1	T57	D62Y	62	Missense	distal	5	no	13.731	13.418	EPSD;PhosphoSitePlus	COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P38936	CDKN1A	P28482	MAPK1	T57	D62H	62	Missense	distal	5	no	13.731	13.561	EPSD;PhosphoSitePlus	COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P38936	CDKN1A	P28482	MAPK1	T57	D52V	52	Missense	distal	-5	no	13.731	13.757	EPSD;PhosphoSitePlus	COSMIC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P38936	CDKN1A	P28482	MAPK1	T57	T57R	57	Missense	central	0	yes	13.731	0.000	EPSD;PhosphoSitePlus	COSMIC	8.102	Loss
CMGC_MAPK_ERK1_MAPK1_ST	P38936	CDKN1A	P28482	MAPK1	S98	T97I	97	Missense	proximal	-1	no	14.815	14.791	EPSD;PhosphoSitePlus	COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P38936	CDKN1A	P28482	MAPK1	S130	E125Q	125	Missense	distal	-5	no	14.369	14.469	PhosphoSitePlus;EPSD	COSMIC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P38936	CDKN1A	P28482	MAPK1	S130	S137T	137	Missense	distal	7	no	14.369	14.521	PhosphoSitePlus;EPSD	COSMIC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P38936	CDKN1A	P28482	MAPK1	T145	D149N	149	Missense	distal	4	no	8.060	8.120	EPSD	COSMIC	8.102	Gain
CMGC_MAPK_ERK1_MAPK1_ST	P07101	TH	P28482	MAPK1	T3	A6T	6	Missense	distal	3	no	11.473	11.456	EPSD	COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P07101	TH	P28482	MAPK1	T3	A6P	6	Missense	distal	3	no	11.473	11.394	EPSD	COSMIC;GDSC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P07101	TH	P28482	MAPK1	T8	R15S	15	Missense	distal	7	no	13.715	13.711	EPSD	COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P07101	TH	P28482	MAPK1	T8	A6T	6	Missense	proximal	-2	no	13.715	14.162	EPSD	COSMIC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P07101	TH	P28482	MAPK1	T8	A6P	6	Missense	proximal	-2	no	13.715	16.861	EPSD	COSMIC;GDSC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P07101	TH	P28482	MAPK1	S19	A17V	17	Missense	proximal	-2	no	7.005	8.279	EPSD	COSMIC;CCLE	8.102	Gain
CMGC_MAPK_ERK1_MAPK1_ST	P07101	TH	P28482	MAPK1	S62	R64Q	64	Missense	proximal	2	no	16.623	16.331	EPSD;PhosphoSitePlus	COSMIC;CCLE	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P07101	TH	P28482	MAPK1	S118	V112M	112	Missense	distal	-6	no	14.340	14.342	EPSD	COSMIC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P07101	TH	P28482	MAPK1	S118	R120S	120	Missense	proximal	2	no	14.340	14.199	EPSD	COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P07101	TH	P28482	MAPK1	S502	S509F	509	Missense	distal	7	no	14.862	15.209	EPSD	COSMIC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P07101	TH	P28482	MAPK1	S502	V506M	506	Missense	distal	4	no	14.862	14.773	EPSD	COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P07101	TH	P28482	MAPK1	S502	P503H	503	Missense	proximal	1	no	14.862	7.038	EPSD	COSMIC	8.102	Loss
CMGC_MAPK_ERK1_MAPK1_ST	Q9NYA1	SPHK1	P28482	MAPK1	T193	L194P	194	Missense	proximal	1	no	6.203	15.013	EPSD	COSMIC	8.102	Gain
CMGC_MAPK_ERK1_MAPK1_ST	Q9NYA1	SPHK1	P28482	MAPK1	S225	G219A	219	Missense	distal	-6	no	18.191	18.194	PhosphoSitePlus	COSMIC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P15336	ATF2	P28482	MAPK1	T69	T73A	73	Missense	distal	4	no	13.621	13.641	EPSD	COSMIC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P15336	ATF2	P28482	MAPK1	T69	F75L	75	Missense	distal	6	no	13.621	13.655	EPSD	COSMIC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P15336	ATF2	P28482	MAPK1	T69	R74T	74	Missense	distal	5	no	13.621	13.516	EPSD	COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P15336	ATF2	P28482	MAPK1	T69	I64V	64	Missense	distal	-5	no	13.621	13.508	EPSD	COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P15336	ATF2	P28482	MAPK1	T69	D67E	67	Missense	proximal	-2	no	13.621	14.543	EPSD	COSMIC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P15336	ATF2	P28482	MAPK1	T71	T73A	73	Missense	proximal	2	no	13.125	13.046	PhosphoSitePlus	COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P15336	ATF2	P28482	MAPK1	T71	F75L	75	Missense	distal	4	no	13.125	13.193	PhosphoSitePlus	COSMIC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P15336	ATF2	P28482	MAPK1	T71	R74T	74	Missense	distal	3	no	13.125	13.141	PhosphoSitePlus	COSMIC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P15336	ATF2	P28482	MAPK1	T71	I64V	64	Missense	distal	-7	no	13.125	13.138	PhosphoSitePlus	COSMIC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P15336	ATF2	P28482	MAPK1	T71	D67E	67	Missense	distal	-4	no	13.125	13.111	PhosphoSitePlus	COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P15336	ATF2	P28482	MAPK1	S90	P91S	91	Missense	proximal	1	no	15.863	6.468	EPSD	COSMIC	8.102	Loss
CMGC_MAPK_ERK1_MAPK1_ST	P15336	ATF2	P28482	MAPK1	S90	A89V	89	Missense	proximal	-1	no	15.863	15.874	EPSD	COSMIC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P15336	ATF2	P28482	MAPK1	S90	P91L	91	Missense	proximal	1	no	15.863	7.053	EPSD	COSMIC	8.102	Loss
CMGC_MAPK_ERK1_MAPK1_ST	P15336	ATF2	P28482	MAPK1	S90	G83C	83	Missense	distal	-7	no	15.863	15.844	EPSD	COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P15336	ATF2	P28482	MAPK1	S112	M107I	107	Missense	distal	-5	no	14.019	14.076	EPSD	COSMIC;GDSC;CCLE	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P15336	ATF2	P28482	MAPK1	S112	K105T	105	Missense	distal	-7	no	14.019	14.004	EPSD	COSMIC;GDSC;CCLE	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P15336	ATF2	P28482	MAPK1	S112	K106R	106	Missense	distal	-6	no	14.019	14.042	EPSD	COSMIC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P15336	ATF2	P28482	MAPK1	S112	D110E	110	Missense	proximal	-2	no	14.019	14.941	EPSD	COSMIC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P15336	ATF2	P28482	MAPK1	T116	D110E	110	Missense	distal	-6	no	14.471	14.459	EPSD	COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P15336	ATF2	P28482	MAPK1	S136	P141T	141	Missense	distal	5	no	14.697	14.641	EPSD	COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P15336	ATF2	P28482	MAPK1	S136	P141L	141	Missense	distal	5	no	14.697	14.484	EPSD	COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P15336	ATF2	P28482	MAPK1	S136	P137S	137	Missense	proximal	1	no	14.697	5.302	EPSD	COSMIC	8.102	Loss
CMGC_MAPK_ERK1_MAPK1_ST	P15336	ATF2	P28482	MAPK1	S257	V258F	258	Missense	proximal	1	no	5.969	8.940	EPSD	COSMIC	8.102	Gain
CMGC_MAPK_ERK1_MAPK1_ST	P15336	ATF2	P28482	MAPK1	S265	S266P	266	Missense	proximal	1	no	3.786	13.181	EPSD	COSMIC	8.102	Gain
CMGC_MAPK_ERK1_MAPK1_ST	P15336	ATF2	P28482	MAPK1	S266	S266P	266	Missense	central	0	yes	16.425	0.000	EPSD	COSMIC	8.102	Loss
CMGC_MAPK_ERK1_MAPK1_ST	P15336	ATF2	P28482	MAPK1	S266	P269Q	269	Missense	distal	3	no	16.425	16.493	EPSD	COSMIC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P15336	ATF2	P28482	MAPK1	S266	S265F	265	Missense	proximal	-1	no	16.425	16.378	EPSD	COSMIC;GDSC;CCLE	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P15336	ATF2	P28482	MAPK1	S266	P269S	269	Missense	distal	3	no	16.425	16.494	EPSD	COSMIC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P15336	ATF2	P28482	MAPK1	S314	R311Q	311	Missense	distal	-3	no	8.196	7.919	EPSD	COSMIC;GDSC;CCLE	8.102	Loss
CMGC_MAPK_ERK1_MAPK1_ST	P15336	ATF2	P28482	MAPK1	S314	Q316K	316	Missense	proximal	2	no	8.196	8.307	EPSD	COSMIC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P15336	ATF2	P28482	MAPK1	S314	Q317H	317	Missense	distal	3	no	8.196	8.217	EPSD	COSMIC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P15336	ATF2	P28482	MAPK1	T320	P326L	326	Missense	distal	6	no	8.431	8.025	EPSD	COSMIC;GDSC	8.102	Loss
CMGC_MAPK_ERK1_MAPK1_ST	P15336	ATF2	P28482	MAPK1	T320	P326T	326	Missense	distal	6	no	8.431	8.221	EPSD	COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P15336	ATF2	P28482	MAPK1	T320	Q316K	316	Missense	distal	-4	no	8.431	8.613	EPSD	COSMIC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P15336	ATF2	P28482	MAPK1	T320	Q317H	317	Missense	distal	-3	no	8.431	8.379	EPSD	COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P15336	ATF2	P28482	MAPK1	T325	P326L	326	Missense	proximal	1	no	13.109	4.299	EPSD	COSMIC;GDSC	8.102	Loss
CMGC_MAPK_ERK1_MAPK1_ST	P15336	ATF2	P28482	MAPK1	T325	P326T	326	Missense	proximal	1	no	13.109	4.610	EPSD	COSMIC	8.102	Loss
CMGC_MAPK_ERK1_MAPK1_ST	P15336	ATF2	P28482	MAPK1	T325	H331Y	331	Missense	distal	6	no	13.109	12.796	EPSD	COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P15336	ATF2	P28482	MAPK1	S328	P326L	326	Missense	proximal	-2	no	17.310	15.393	EPSD	COSMIC;GDSC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P15336	ATF2	P28482	MAPK1	S328	P326T	326	Missense	proximal	-2	no	17.310	14.611	EPSD	COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P15336	ATF2	P28482	MAPK1	S328	Q335H	335	Missense	distal	7	no	17.310	17.414	EPSD	COSMIC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P15336	ATF2	P28482	MAPK1	S328	H331Y	331	Missense	distal	3	no	17.310	17.348	EPSD	COSMIC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P15336	ATF2	P28482	MAPK1	T333	Q337K	337	Missense	distal	4	no	14.496	14.581	EPSD	COSMIC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P15336	ATF2	P28482	MAPK1	T333	P326L	326	Missense	distal	-7	no	14.496	14.484	EPSD	COSMIC;GDSC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P15336	ATF2	P28482	MAPK1	T333	P326T	326	Missense	distal	-7	no	14.496	14.479	EPSD	COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P15336	ATF2	P28482	MAPK1	T333	Q335H	335	Missense	proximal	2	no	14.496	14.545	EPSD	COSMIC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P15336	ATF2	P28482	MAPK1	T333	P334S	334	Missense	proximal	1	no	14.496	5.101	EPSD	COSMIC	8.102	Loss
CMGC_MAPK_ERK1_MAPK1_ST	P15336	ATF2	P28482	MAPK1	T333	H331Y	331	Missense	proximal	-2	no	14.496	15.134	EPSD	COSMIC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P15336	ATF2	P28482	MAPK1	S446	S442L	442	Missense	distal	-4	no	17.002	16.781	EPSD	COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P15336	ATF2	P28482	MAPK1	S446	P444L	444	Missense	proximal	-2	no	17.002	15.084	EPSD	COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P15336	ATF2	P28482	MAPK1	S446	P444T	444	Missense	proximal	-2	no	17.002	14.302	EPSD	COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P15336	ATF2	P28482	MAPK1	S446	S442P	442	Missense	distal	-4	no	17.002	17.085	EPSD	COSMIC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P15336	ATF2	P28482	MAPK1	S446	P444Q	444	Missense	proximal	-2	no	17.002	14.008	EPSD	COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P15336	ATF2	P28482	MAPK1	T449	S442L	442	Missense	distal	-7	no	8.252	8.244	EPSD	COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P15336	ATF2	P28482	MAPK1	T449	P444L	444	Missense	distal	-5	no	8.252	8.400	EPSD	COSMIC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P15336	ATF2	P28482	MAPK1	T449	P444T	444	Missense	distal	-5	no	8.252	8.354	EPSD	COSMIC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P15336	ATF2	P28482	MAPK1	T449	S442P	442	Missense	distal	-7	no	8.252	8.256	EPSD	COSMIC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P15336	ATF2	P28482	MAPK1	T449	P444Q	444	Missense	distal	-5	no	8.252	8.376	EPSD	COSMIC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P15336	ATF2	P28482	MAPK1	T449	S455T	455	Missense	distal	6	no	8.252	8.041	EPSD	COSMIC	8.102	Loss
CMGC_MAPK_ERK1_MAPK1_ST	P15336	ATF2	P28482	MAPK1	S498	V493I	493	Missense	distal	-5	no	9.490	9.603	EPSD	COSMIC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P15336	ATF2	P28482	MAPK1	S498	Q501K	501	Missense	distal	3	no	9.490	9.420	EPSD	COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P15336	ATF2	P28482	MAPK1	S500	V493I	493	Missense	distal	-7	no	8.284	8.271	EPSD	COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P15336	ATF2	P28482	MAPK1	S500	Q501K	501	Missense	proximal	1	no	8.284	-1.742	EPSD	COSMIC	8.102	Loss
CMGC_MAPK_ERK1_MAPK1_ST	P23443	RPS6KB1	P28482	MAPK1	T252	H245Y	245	Missense	distal	-7	no	9.245	9.226	EPSD	COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P23443	RPS6KB1	P28482	MAPK1	T390	P391S	391	Missense	proximal	1	no	15.492	6.097	EPSD	COSMIC	8.102	Loss
CMGC_MAPK_ERK1_MAPK1_ST	P23443	RPS6KB1	P28482	MAPK1	T390	R388G	388	Missense	proximal	-2	no	15.492	14.117	EPSD	COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P23443	RPS6KB1	P28482	MAPK1	S394	P391S	391	Missense	distal	-3	no	15.731	15.554	EPSD	COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P23443	RPS6KB1	P28482	MAPK1	S394	S401N	401	Missense	distal	7	no	15.731	15.713	EPSD	COSMIC;CCLE	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P23443	RPS6KB1	P28482	MAPK1	S394	S398T	398	Missense	distal	4	no	15.731	15.618	EPSD	COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P23443	RPS6KB1	P28482	MAPK1	S394	R388G	388	Missense	distal	-6	no	15.731	15.680	EPSD	COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P23443	RPS6KB1	P28482	MAPK1	S434	I432T	432	Missense	proximal	-2	no	14.040	13.235	EPSD;PhosphoSitePlus	COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P23443	RPS6KB1	P28482	MAPK1	S434	G440A	440	Missense	distal	6	no	14.040	13.821	EPSD;PhosphoSitePlus	COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P23443	RPS6KB1	P28482	MAPK1	S434	R436Q	436	Missense	proximal	2	no	14.040	13.749	EPSD;PhosphoSitePlus	COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P23443	RPS6KB1	P28482	MAPK1	S434	E429Q	429	Missense	distal	-5	no	14.040	14.140	EPSD;PhosphoSitePlus	COSMIC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P23443	RPS6KB1	P28482	MAPK1	S441	G440A	440	Missense	proximal	-1	no	15.595	15.612	EPSD	COSMIC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P23443	RPS6KB1	P28482	MAPK1	S441	P445L	445	Missense	distal	4	no	15.595	15.474	EPSD	COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P23443	RPS6KB1	P28482	MAPK1	S441	R436Q	436	Missense	distal	-5	no	15.595	15.672	EPSD	COSMIC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P23443	RPS6KB1	P28482	MAPK1	T444	G440A	440	Missense	distal	-4	no	17.708	17.765	EPSD;PhosphoSitePlus	COSMIC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P23443	RPS6KB1	P28482	MAPK1	T444	P445L	445	Missense	proximal	1	no	17.708	8.898	EPSD;PhosphoSitePlus	COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P23443	RPS6KB1	P28482	MAPK1	S447	G440A	440	Missense	distal	-7	no	18.223	18.239	PhosphoSitePlus;EPSD	COSMIC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P23443	RPS6KB1	P28482	MAPK1	S447	P445L	445	Missense	proximal	-2	no	18.223	16.306	PhosphoSitePlus;EPSD	COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P23443	RPS6KB1	P28482	MAPK1	S447	G454W	454	Missense	distal	7	no	18.223	19.129	PhosphoSitePlus;EPSD	COSMIC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P23443	RPS6KB1	P28482	MAPK1	S452	P445L	445	Missense	distal	-7	no	13.550	13.537	EPSD	COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P23443	RPS6KB1	P28482	MAPK1	S452	G454W	454	Missense	proximal	2	no	13.550	13.276	EPSD	COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P23443	RPS6KB1	P28482	MAPK1	T470	S464N	464	Missense	distal	-6	no	15.019	15.023	EPSD	COSMIC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P23443	RPS6KB1	P28482	MAPK1	T470	P468T	468	Missense	proximal	-2	no	15.019	12.320	EPSD	COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P23443	RPS6KB1	P28482	MAPK1	S503	I498L	498	Missense	distal	-5	no	10.561	10.501	EPSD	COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P23443	RPS6KB1	P28482	MAPK1	S503	G504R	504	Missense	proximal	1	no	10.561	10.973	EPSD	COSMIC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P23443	RPS6KB1	P28482	MAPK1	S503	K508Q	508	Missense	distal	5	no	10.561	10.526	EPSD	COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q92934	BAD	P28482	MAPK1	S25	A27T	27	Missense	proximal	2	no	16.358	16.437	EPSD	COSMIC;GDSC;CCLE	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q92934	BAD	P28482	MAPK1	S57	E53K	53	Missense	distal	-4	no	8.424	8.442	EPSD	COSMIC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q92934	BAD	P28482	MAPK1	S57	S59R	59	Missense	proximal	2	no	8.424	8.565	EPSD	COSMIC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q92934	BAD	P28482	MAPK1	S75	A78E	78	Missense	distal	3	no	9.338	9.251	PhosphoSitePlus	COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q92934	BAD	P28482	MAPK1	S91	R98H	98	Missense	distal	7	no	15.443	15.662	EPSD	COSMIC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q92934	BAD	P28482	MAPK1	S124	S124F	124	Missense	central	0	yes	8.838	0.000	EPSD	COSMIC	8.102	Loss
CMGC_MAPK_ERK1_MAPK1_ST	Q92934	BAD	P28482	MAPK1	S124	K127N	127	Missense	distal	3	no	8.838	8.832	EPSD	COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q92934	BAD	P28482	MAPK1	S134	K133N	133	Missense	proximal	-1	no	8.841	8.833	EPSD	COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q92934	BAD	P28482	MAPK1	S146	W147R	147	Missense	proximal	1	no	8.396	6.118	EPSD	COSMIC	8.102	Loss
CMGC_MAPK_ERK1_MAPK1_ST	Q92934	BAD	P28482	MAPK1	S153	W147R	147	Missense	distal	-6	no	8.934	9.154	EPSD	COSMIC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q9GZM8	NDEL1	P28482	MAPK1	S198	P196S	196	Missense	proximal	-2	no	15.698	12.864	EPSD	COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q9GZM8	NDEL1	P28482	MAPK1	S198	K205N	205	Missense	distal	7	no	15.698	15.733	EPSD	COSMIC;GDSC;CCLE	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q9GZM8	NDEL1	P28482	MAPK1	S198	L201P	201	Missense	distal	3	no	15.698	15.609	EPSD	COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q9GZM8	NDEL1	P28482	MAPK1	T200	L201P	201	Missense	proximal	1	no	3.993	12.803	EPSD	COSMIC	8.102	Gain
CMGC_MAPK_ERK1_MAPK1_ST	Q9GZM8	NDEL1	P28482	MAPK1	T219	T219I	219	Missense	central	0	yes	15.912	0.000	EPSD;PhosphoSitePlus	COSMIC	8.102	Loss
CMGC_MAPK_ERK1_MAPK1_ST	Q9GZM8	NDEL1	P28482	MAPK1	S231	T228I	228	Missense	distal	-3	no	17.036	16.804	EPSD	COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q9GZM8	NDEL1	P28482	MAPK1	S242	G240S	240	Missense	proximal	-2	no	13.403	13.763	EPSD	COSMIC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q9GZM8	NDEL1	P28482	MAPK1	T245	G240S	240	Missense	distal	-5	no	14.863	14.870	PhosphoSitePlus;EPSD	COSMIC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q9GZM8	NDEL1	P28482	MAPK1	S331	P326L	326	Missense	distal	-5	no	9.062	9.210	EPSD	COSMIC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q9GZM8	NDEL1	P28482	MAPK1	S331	R333H	333	Missense	proximal	2	no	9.062	8.818	EPSD	COSMIC;GDSC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q9GZM8	NDEL1	P28482	MAPK1	S331	P324T	324	Missense	distal	-7	no	9.062	9.045	EPSD	COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q9GZM8	NDEL1	P28482	MAPK1	S331	P338S	338	Missense	distal	7	no	9.062	9.072	EPSD	COSMIC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q9GZM8	NDEL1	P28482	MAPK1	S332	R333H	333	Missense	proximal	1	no	6.274	8.104	EPSD	COSMIC;GDSC	8.102	Gain
CMGC_MAPK_ERK1_MAPK1_ST	Q9GZM8	NDEL1	P28482	MAPK1	S336	R333H	333	Missense	distal	-3	no	12.479	12.149	EPSD	COSMIC;GDSC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q9GZM8	NDEL1	P28482	MAPK1	S336	P338S	338	Missense	proximal	2	no	12.479	12.451	EPSD	COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q9GZM8	NDEL1	P28482	MAPK1	S344	P338S	338	Missense	distal	-6	no	8.706	8.680	EPSD	COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q07343	PDE4B	P28482	MAPK1	S106	S113N	113	Missense	distal	7	no	12.998	12.980	EPSD	COSMIC;CCLE	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q07343	PDE4B	P28482	MAPK1	S106	G104D	104	Missense	proximal	-2	no	12.998	12.890	EPSD	COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q07343	PDE4B	P28482	MAPK1	S106	P107T	107	Missense	proximal	1	no	12.998	4.499	EPSD	COSMIC	8.102	Loss
CMGC_MAPK_ERK1_MAPK1_ST	Q07343	PDE4B	P28482	MAPK1	S106	P103S	103	Missense	distal	-3	no	12.998	12.821	EPSD	COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q07343	PDE4B	P28482	MAPK1	S106	R105Q	105	Missense	proximal	-1	no	12.998	12.976	EPSD	COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q07343	PDE4B	P28482	MAPK1	S115	S113N	113	Missense	proximal	-2	no	8.165	8.179	EPSD	COSMIC;CCLE	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q07343	PDE4B	P28482	MAPK1	S145	P146L	146	Missense	proximal	1	no	12.524	3.714	EPSD	COSMIC	8.102	Loss
CMGC_MAPK_ERK1_MAPK1_ST	Q07343	PDE4B	P28482	MAPK1	S145	A148V	148	Missense	distal	3	no	12.524	12.503	EPSD	COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q07343	PDE4B	P28482	MAPK1	S145	A148E	148	Missense	distal	3	no	12.524	12.437	EPSD	COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q07343	PDE4B	P28482	MAPK1	S145	D139Y	139	Missense	distal	-6	no	12.524	12.361	EPSD	COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q07343	PDE4B	P28482	MAPK1	S153	S154F	154	Missense	proximal	1	no	5.695	8.521	EPSD	COSMIC	8.102	Gain
CMGC_MAPK_ERK1_MAPK1_ST	Q07343	PDE4B	P28482	MAPK1	T167	P168A	168	Missense	proximal	1	no	14.341	6.710	EPSD	COSMIC	8.102	Loss
CMGC_MAPK_ERK1_MAPK1_ST	Q07343	PDE4B	P28482	MAPK1	S197	H190L	190	Missense	distal	-7	no	14.069	14.073	EPSD	COSMIC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q07343	PDE4B	P28482	MAPK1	S197	A199D	199	Missense	proximal	2	no	14.069	14.183	EPSD	COSMIC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q07343	PDE4B	P28482	MAPK1	S197	P198T	198	Missense	proximal	1	no	14.069	5.571	EPSD	COSMIC	8.102	Loss
CMGC_MAPK_ERK1_MAPK1_ST	Q07343	PDE4B	P28482	MAPK1	S197	S201T	201	Missense	distal	4	no	14.069	13.956	EPSD	COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q07343	PDE4B	P28482	MAPK1	S197	S193C	193	Missense	distal	-4	no	14.069	13.426	EPSD	COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q07343	PDE4B	P28482	MAPK1	S197	Q202H	202	Missense	distal	5	no	14.069	14.063	EPSD	COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q07343	PDE4B	P28482	MAPK1	S201	Q202H	202	Missense	proximal	1	no	7.650	8.320	EPSD	COSMIC	8.102	Gain
CMGC_MAPK_ERK1_MAPK1_ST	Q07343	PDE4B	P28482	MAPK1	S290	E297K	297	Missense	distal	7	no	13.483	13.490	EPSD	COSMIC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q07343	PDE4B	P28482	MAPK1	S601	D605N	605	Missense	distal	4	no	11.994	12.053	EPSD	COSMIC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q07343	PDE4B	P28482	MAPK1	S601	M603I	603	Missense	proximal	2	no	11.994	12.014	EPSD	COSMIC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q07343	PDE4B	P28482	MAPK1	S601	R596M	596	Missense	distal	-5	no	11.994	12.099	EPSD	COSMIC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q07343	PDE4B	P28482	MAPK1	S601	R594G	594	Missense	distal	-7	no	11.994	11.981	EPSD	COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q07343	PDE4B	P28482	MAPK1	S601	R594Q	594	Missense	distal	-7	no	11.994	12.002	EPSD	COSMIC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q07343	PDE4B	P28482	MAPK1	S659	P663L	663	Missense	distal	4	no	17.106	16.985	PhosphoSitePlus;EPSD	COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q07343	PDE4B	P28482	MAPK1	S659	S654R	654	Missense	distal	-5	no	17.106	17.079	PhosphoSitePlus;EPSD	COSMIC;GDSC;CCLE	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q07343	PDE4B	P28482	MAPK1	S659	E666K	666	Missense	distal	7	no	17.106	17.114	PhosphoSitePlus;EPSD	COSMIC;GDSC;CCLE	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q07343	PDE4B	P28482	MAPK1	S661	P663L	663	Missense	proximal	2	no	12.819	12.672	EPSD	COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q07343	PDE4B	P28482	MAPK1	S661	S654R	654	Missense	distal	-7	no	12.819	12.818	EPSD	COSMIC;GDSC;CCLE	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q07343	PDE4B	P28482	MAPK1	S661	E666K	666	Missense	distal	5	no	12.819	12.760	EPSD	COSMIC;GDSC;CCLE	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q07343	PDE4B	P28482	MAPK1	S732	T728S	728	Missense	distal	-4	no	14.019	14.249	EPSD	COSMIC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q07343	PDE4B	P28482	MAPK1	S732	D725A	725	Missense	distal	-7	no	14.019	14.020	EPSD	COSMIC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q07343	PDE4B	P28482	MAPK1	S732	P733H	733	Missense	proximal	1	no	14.019	6.196	EPSD	COSMIC	8.102	Loss
CMGC_MAPK_ERK1_MAPK1_ST	Q07343	PDE4B	P28482	MAPK1	S732	V734M	734	Missense	proximal	2	no	14.019	13.882	EPSD	COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q9H8Y8	GORASP2	P28482	MAPK1	T222	P223H	223	Missense	proximal	1	no	14.584	6.760	PhosphoSitePlus;EPSD	COSMIC	8.102	Loss
CMGC_MAPK_ERK1_MAPK1_ST	Q9H8Y8	GORASP2	P28482	MAPK1	T222	P226S	226	Missense	distal	4	no	14.584	14.573	PhosphoSitePlus;EPSD	COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q9H8Y8	GORASP2	P28482	MAPK1	T222	D229N	229	Missense	distal	7	no	14.584	14.571	PhosphoSitePlus;EPSD	COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q9H8Y8	GORASP2	P28482	MAPK1	T225	P223H	223	Missense	proximal	-2	no	15.342	12.587	EPSD;PhosphoSitePlus	COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q9H8Y8	GORASP2	P28482	MAPK1	T225	P226S	226	Missense	proximal	1	no	15.342	5.947	EPSD;PhosphoSitePlus	COSMIC	8.102	Loss
CMGC_MAPK_ERK1_MAPK1_ST	Q9H8Y8	GORASP2	P28482	MAPK1	T225	D229N	229	Missense	distal	4	no	15.342	15.402	EPSD;PhosphoSitePlus	COSMIC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q9H8Y8	GORASP2	P28482	MAPK1	S245	S243Y	243	Missense	proximal	-2	no	13.653	14.370	EPSD	COSMIC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q9H8Y8	GORASP2	P28482	MAPK1	S245	P241S	241	Missense	distal	-4	no	13.653	13.569	EPSD	COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q9H8Y8	GORASP2	P28482	MAPK1	S245	I252M	252	Missense	distal	7	no	13.653	13.465	EPSD	COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q9H8Y8	GORASP2	P28482	MAPK1	T249	S243Y	243	Missense	distal	-6	no	8.553	8.439	EPSD	COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q9H8Y8	GORASP2	P28482	MAPK1	T249	I252M	252	Missense	distal	3	no	8.553	8.510	EPSD	COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q9H8Y8	GORASP2	P28482	MAPK1	S386	L387F	387	Missense	proximal	1	no	7.474	9.715	EPSD	COSMIC	8.102	Gain
CMGC_MAPK_ERK1_MAPK1_ST	Q9H8Y8	GORASP2	P28482	MAPK1	T415	P416S	416	Missense	proximal	1	no	13.623	4.228	EPSD	COSMIC	8.102	Loss
CMGC_MAPK_ERK1_MAPK1_ST	Q9H8Y8	GORASP2	P28482	MAPK1	T418	P416S	416	Missense	proximal	-2	no	8.875	6.041	EPSD	COSMIC	8.102	Loss
CMGC_MAPK_ERK1_MAPK1_ST	Q9H8Y8	GORASP2	P28482	MAPK1	S441	A446V	446	Missense	distal	5	no	11.560	11.577	EPSD	COSMIC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q9H8Y8	GORASP2	P28482	MAPK1	S451	E450V	450	Missense	proximal	-1	no	15.489	15.478	EPSD	COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q9H8Y8	GORASP2	P28482	MAPK1	S451	A446V	446	Missense	distal	-5	no	15.489	15.460	EPSD	COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P19793	RXRA	P28482	MAPK1	S49	P50S	50	Missense	proximal	1	no	14.718	5.323	EPSD	COSMIC;GDSC;CCLE	8.102	Loss
CMGC_MAPK_ERK1_MAPK1_ST	P19793	RXRA	P28482	MAPK1	S66	G60V	60	Missense	distal	-6	no	8.522	8.479	EPSD	COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P19793	RXRA	P28482	MAPK1	T82	G86C	86	Missense	distal	4	no	16.735	16.502	EPSD	COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P19793	RXRA	P28482	MAPK1	S225	D229G	229	Missense	distal	4	no	8.135	8.183	EPSD	COSMIC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P19793	RXRA	P28482	MAPK1	S225	S222L	222	Missense	distal	-3	no	8.135	7.928	EPSD	COSMIC	8.102	Loss
CMGC_MAPK_ERK1_MAPK1_ST	P19793	RXRA	P28482	MAPK1	S260	M254I	254	Missense	distal	-6	no	17.748	17.705	PhosphoSitePlus	COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	O43623	SNAI2	P28482	MAPK1	S54	P55S	55	Missense	proximal	1	no	13.694	4.299	EPSD	COSMIC	8.102	Loss
CMGC_MAPK_ERK1_MAPK1_ST	O43623	SNAI2	P28482	MAPK1	S87	P88L	88	Missense	proximal	1	no	18.083	9.273	PhosphoSitePlus;EPSD	COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	O43623	SNAI2	P28482	MAPK1	S104	D98N	98	Missense	distal	-6	no	15.466	15.420	EPSD;PhosphoSitePlus	COSMIC;GDSC;CCLE	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	O43623	SNAI2	P28482	MAPK1	S104	G101D	101	Missense	distal	-3	no	15.466	15.526	EPSD;PhosphoSitePlus	COSMIC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	O43623	SNAI2	P28482	MAPK1	T234	K239R	239	Missense	distal	5	no	8.283	8.418	EPSD	COSMIC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	O43623	SNAI2	P28482	MAPK1	S254	K258N	258	Missense	distal	4	no	9.162	9.137	EPSD	COSMIC;GDSC;CCLE	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	O43623	SNAI2	P28482	MAPK1	S254	L255P	255	Missense	proximal	1	no	9.162	17.971	EPSD	COSMIC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	O43623	SNAI2	P28482	MAPK1	S254	S251C	251	Missense	distal	-3	no	9.162	8.635	EPSD	COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P78536	ADAM17	P28482	MAPK1	T822	E823A	823	Missense	proximal	1	no	7.122	8.263	EPSD	COSMIC	8.102	Gain
CMGC_MAPK_ERK1_MAPK1_ST	Q8WX93	PALLD	P28482	MAPK1	S9	D16Y	16	Missense	distal	7	no	7.679	8.201	EPSD	COSMIC	8.102	Gain
CMGC_MAPK_ERK1_MAPK1_ST	Q8WX93	PALLD	P28482	MAPK1	S15	D16Y	16	Missense	proximal	1	no	8.108	9.795	EPSD	COSMIC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q8WX93	PALLD	P28482	MAPK1	S15	F10L	10	Missense	distal	-5	no	8.108	8.094	EPSD	COSMIC;CCLE	8.102	Loss
CMGC_MAPK_ERK1_MAPK1_ST	Q8WX93	PALLD	P28482	MAPK1	S71	P72T	72	Missense	proximal	1	no	13.470	4.971	EPSD	COSMIC	8.102	Loss
CMGC_MAPK_ERK1_MAPK1_ST	Q8WX93	PALLD	P28482	MAPK1	S71	I64F	64	Missense	distal	-7	no	13.470	13.478	EPSD	COSMIC;CCLE	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q8WX93	PALLD	P28482	MAPK1	T100	E107Q	107	Missense	distal	7	no	14.453	14.630	EPSD	COSMIC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q8WX93	PALLD	P28482	MAPK1	S115	P116S	116	Missense	proximal	1	no	14.813	5.418	EPSD	COSMIC	8.102	Loss
CMGC_MAPK_ERK1_MAPK1_ST	Q8WX93	PALLD	P28482	MAPK1	S115	I113N	113	Missense	proximal	-2	no	14.813	13.887	EPSD	COSMIC;CCLE	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q8WX93	PALLD	P28482	MAPK1	S132	R135G	135	Missense	distal	3	no	8.651	8.688	EPSD	COSMIC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q8WX93	PALLD	P28482	MAPK1	S132	R135Q	135	Missense	distal	3	no	8.651	8.673	EPSD	COSMIC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q8WX93	PALLD	P28482	MAPK1	S132	S136G	136	Missense	distal	4	no	8.651	8.602	EPSD	COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q8WX93	PALLD	P28482	MAPK1	T147	V152I	152	Missense	distal	5	no	10.837	10.662	EPSD	COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q8WX93	PALLD	P28482	MAPK1	T147	R143H	143	Missense	distal	-4	no	10.837	10.685	EPSD	COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q8WX93	PALLD	P28482	MAPK1	S192	G195E	195	Missense	distal	3	no	10.428	10.335	EPSD	COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q8WX93	PALLD	P28482	MAPK1	S192	K187R	187	Missense	distal	-5	no	10.428	10.473	EPSD	COSMIC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q8WX93	PALLD	P28482	MAPK1	S199	D201H	201	Missense	proximal	2	no	12.436	12.322	EPSD	COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q8WX93	PALLD	P28482	MAPK1	S199	S206P	206	Missense	distal	7	no	12.436	12.425	EPSD	COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q8WX93	PALLD	P28482	MAPK1	S199	G195E	195	Missense	distal	-4	no	12.436	12.757	EPSD	COSMIC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q8WX93	PALLD	P28482	MAPK1	S206	N209D	209	Missense	distal	3	no	14.383	14.479	EPSD	COSMIC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q8WX93	PALLD	P28482	MAPK1	S206	D201H	201	Missense	distal	-5	no	14.383	14.438	EPSD	COSMIC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q8WX93	PALLD	P28482	MAPK1	S206	S206P	206	Missense	central	0	yes	14.383	0.000	EPSD	COSMIC	8.102	Loss
CMGC_MAPK_ERK1_MAPK1_ST	Q8WX93	PALLD	P28482	MAPK1	S222	M224I	224	Missense	proximal	2	no	14.479	14.499	EPSD	COSMIC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q8WX93	PALLD	P28482	MAPK1	S222	M224T	224	Missense	proximal	2	no	14.479	14.620	EPSD	COSMIC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q8WX93	PALLD	P28482	MAPK1	S222	E225A	225	Missense	distal	3	no	14.479	14.566	EPSD	COSMIC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q8WX93	PALLD	P28482	MAPK1	S236	M230I	230	Missense	distal	-6	no	14.164	14.121	EPSD	COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q8WX93	PALLD	P28482	MAPK1	S236	P237S	237	Missense	proximal	1	no	14.164	4.769	EPSD	COSMIC	8.102	Loss
CMGC_MAPK_ERK1_MAPK1_ST	Q8WX93	PALLD	P28482	MAPK1	S236	G238E	238	Missense	proximal	2	no	14.164	14.078	EPSD	COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q8WX93	PALLD	P28482	MAPK1	S236	G238V	238	Missense	proximal	2	no	14.164	14.092	EPSD	COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q8WX93	PALLD	P28482	MAPK1	S236	S236Y	236	Missense	central	0	yes	14.164	0.000	EPSD	COSMIC;GDSC;CCLE	8.102	Loss
CMGC_MAPK_ERK1_MAPK1_ST	Q8WX93	PALLD	P28482	MAPK1	S401	P402S	402	Missense	proximal	1	no	14.094	4.699	EPSD	COSMIC	8.102	Loss
CMGC_MAPK_ERK1_MAPK1_ST	Q8WX93	PALLD	P28482	MAPK1	S401	G405R	405	Missense	distal	4	no	14.094	14.121	EPSD	COSMIC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q8WX93	PALLD	P28482	MAPK1	S401	S399L	399	Missense	proximal	-2	no	14.094	15.011	EPSD	COSMIC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q8WX93	PALLD	P28482	MAPK1	S401	P402Q	402	Missense	proximal	1	no	14.094	5.601	EPSD	COSMIC	8.102	Loss
CMGC_MAPK_ERK1_MAPK1_ST	Q8WX93	PALLD	P28482	MAPK1	S423	T425N	425	Missense	proximal	2	no	13.511	13.486	EPSD	COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q8WX93	PALLD	P28482	MAPK1	S484	G478R	478	Missense	distal	-6	no	12.366	12.417	EPSD	COSMIC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q8WX93	PALLD	P28482	MAPK1	S484	R488Q	488	Missense	distal	4	no	12.366	12.291	EPSD	COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q8WX93	PALLD	P28482	MAPK1	S484	G478V	478	Missense	distal	-6	no	12.366	12.323	EPSD	COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q8WX93	PALLD	P28482	MAPK1	S484	G478W	478	Missense	distal	-6	no	12.366	12.197	EPSD	COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q8WX93	PALLD	P28482	MAPK1	S713	S717G	717	Missense	distal	4	no	8.188	8.138	EPSD	COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q8WX93	PALLD	P28482	MAPK1	T751	S755Y	755	Missense	distal	4	no	14.777	14.583	EPSD	COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q8WX93	PALLD	P28482	MAPK1	S754	S755Y	755	Missense	proximal	1	no	7.839	10.225	EPSD	COSMIC	8.102	Gain
CMGC_MAPK_ERK1_MAPK1_ST	Q8WX93	PALLD	P28482	MAPK1	S755	S755Y	755	Missense	central	0	yes	13.916	0.000	EPSD	COSMIC	8.102	Loss
CMGC_MAPK_ERK1_MAPK1_ST	Q8WX93	PALLD	P28482	MAPK1	S830	S835Y	835	Missense	distal	5	no	14.305	14.017	EPSD	COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q8WX93	PALLD	P28482	MAPK1	S830	S835A	835	Missense	distal	5	no	14.305	14.146	EPSD	COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q8WX93	PALLD	P28482	MAPK1	S839	S835Y	835	Missense	distal	-4	no	13.072	12.483	EPSD	COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q8WX93	PALLD	P28482	MAPK1	S839	S835A	835	Missense	distal	-4	no	13.072	12.863	EPSD	COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q8WX93	PALLD	P28482	MAPK1	T877	P878A	878	Missense	proximal	1	no	12.243	4.613	EPSD	COSMIC	8.102	Loss
CMGC_MAPK_ERK1_MAPK1_ST	Q15797	SMAD1	P28482	MAPK1	S11	K15R	15	Missense	distal	4	no	15.056	15.046	EPSD	COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q15797	SMAD1	P28482	MAPK1	S11	K15N	15	Missense	distal	4	no	15.056	15.032	EPSD	COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q15797	SMAD1	P28482	MAPK1	S132	V130L	130	Missense	proximal	-2	no	13.145	13.100	EPSD	COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q15797	SMAD1	P28482	MAPK1	S132	Y127C	127	Missense	distal	-5	no	13.145	13.217	EPSD	COSMIC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q15797	SMAD1	P28482	MAPK1	S187	P188S	188	Missense	proximal	1	no	16.983	7.588	EPSD;PhosphoSitePlus	COSMIC	8.102	Loss
CMGC_MAPK_ERK1_MAPK1_ST	Q15797	SMAD1	P28482	MAPK1	S187	P183L	183	Missense	distal	-4	no	16.983	16.679	EPSD;PhosphoSitePlus	COSMIC;CCLE	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q15797	SMAD1	P28482	MAPK1	S195	P188S	188	Missense	distal	-7	no	16.646	16.642	PhosphoSitePlus;EPSD	COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q15797	SMAD1	P28482	MAPK1	S206	H205Y	205	Missense	proximal	-1	no	16.952	16.920	EPSD;PhosphoSitePlus	COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q15797	SMAD1	P28482	MAPK1	S206	H205N	205	Missense	proximal	-1	no	16.952	17.001	EPSD;PhosphoSitePlus	COSMIC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q15797	SMAD1	P28482	MAPK1	T452	Q445L	445	Missense	distal	-7	no	8.199	8.183	EPSD	COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q13127	REST	P28482	MAPK1	S204	T205P	205	Missense	proximal	1	no	5.643	14.142	EPSD	COSMIC	8.102	Gain
CMGC_MAPK_ERK1_MAPK1_ST	Q13127	REST	P28482	MAPK1	T205	A206P	206	Missense	proximal	1	no	6.462	14.093	EPSD	COSMIC	8.102	Gain
CMGC_MAPK_ERK1_MAPK1_ST	Q13127	REST	P28482	MAPK1	S734	M731I	731	Missense	distal	-3	no	13.489	13.485	EPSD	COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q13127	REST	P28482	MAPK1	S734	E738G	738	Missense	distal	4	no	13.489	13.467	EPSD	COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q13127	REST	P28482	MAPK1	S734	M737I	737	Missense	distal	3	no	13.489	13.532	EPSD	COSMIC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q13127	REST	P28482	MAPK1	S734	V739A	739	Missense	distal	5	no	13.489	13.472	EPSD	COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q13127	REST	P28482	MAPK1	S750	P744L	744	Missense	distal	-6	no	13.959	13.867	EPSD	COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q13127	REST	P28482	MAPK1	S750	P751H	751	Missense	proximal	1	no	13.959	6.135	EPSD	COSMIC	8.102	Loss
CMGC_MAPK_ERK1_MAPK1_ST	Q13127	REST	P28482	MAPK1	S750	P752T	752	Missense	proximal	2	no	13.959	13.908	EPSD	COSMIC;GDSC;CCLE	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q13127	REST	P28482	MAPK1	S750	P744S	744	Missense	distal	-6	no	13.959	13.932	EPSD	COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q13127	REST	P28482	MAPK1	S782	P776A	776	Missense	distal	-6	no	14.177	14.138	EPSD	COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q13127	REST	P28482	MAPK1	S861	L860I	860	Missense	proximal	-1	no	10.701	10.695	PhosphoSitePlus;EPSD	COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q13127	REST	P28482	MAPK1	S864	L860I	860	Missense	distal	-4	no	16.895	16.529	EPSD;PhosphoSitePlus	COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q13127	REST	P28482	MAPK1	S971	V966I	966	Missense	distal	-5	no	16.928	17.041	EPSD	COSMIC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q04637	EIF4G1	P28482	MAPK1	S15	P21L	21	Missense	distal	6	no	16.266	15.859	EPSD	COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q04637	EIF4G1	P28482	MAPK1	S15	P10S	10	Missense	distal	-5	no	16.266	16.340	EPSD	COSMIC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q04637	EIF4G1	P28482	MAPK1	T43	Q49E	49	Missense	distal	6	no	12.314	12.636	EPSD	COSMIC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q04637	EIF4G1	P28482	MAPK1	T43	R48S	48	Missense	distal	5	no	12.314	12.283	EPSD	COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q04637	EIF4G1	P28482	MAPK1	T43	P44S	44	Missense	proximal	1	no	12.314	2.919	EPSD	COSMIC	8.102	Loss
CMGC_MAPK_ERK1_MAPK1_ST	Q04637	EIF4G1	P28482	MAPK1	S54	R55W	55	Missense	proximal	1	no	5.891	8.169	EPSD	COSMIC	8.102	Gain
CMGC_MAPK_ERK1_MAPK1_ST	Q04637	EIF4G1	P28482	MAPK1	S61	S64L	64	Missense	distal	3	no	8.855	8.875	EPSD	COSMIC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q04637	EIF4G1	P28482	MAPK1	S61	R55Q	55	Missense	distal	-6	no	8.855	8.831	EPSD	COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q04637	EIF4G1	P28482	MAPK1	S61	R55W	55	Missense	distal	-6	no	8.855	8.634	EPSD	COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q04637	EIF4G1	P28482	MAPK1	S61	P59L	59	Missense	proximal	-2	no	8.855	6.937	EPSD	COSMIC	8.102	Loss
CMGC_MAPK_ERK1_MAPK1_ST	Q04637	EIF4G1	P28482	MAPK1	S134	T136M	136	Missense	proximal	2	no	14.237	14.097	EPSD	COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q04637	EIF4G1	P28482	MAPK1	S134	G139W	139	Missense	distal	5	no	14.237	13.759	EPSD	COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q04637	EIF4G1	P28482	MAPK1	S134	P131S	131	Missense	distal	-3	no	14.237	14.061	EPSD	COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q04637	EIF4G1	P28482	MAPK1	T205	G199D	199	Missense	distal	-6	no	12.516	12.583	EPSD	COSMIC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q04637	EIF4G1	P28482	MAPK1	T205	P208L	208	Missense	distal	3	no	12.516	12.606	EPSD	COSMIC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q04637	EIF4G1	P28482	MAPK1	T205	S204T	204	Missense	proximal	-1	no	12.516	12.518	EPSD	COSMIC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q04637	EIF4G1	P28482	MAPK1	T205	R201C	201	Missense	distal	-4	no	12.516	11.878	EPSD	COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q04637	EIF4G1	P28482	MAPK1	T205	R201H	201	Missense	distal	-4	no	12.516	12.364	EPSD	COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q04637	EIF4G1	P28482	MAPK1	T205	T211M	211	Missense	distal	6	no	12.516	12.294	EPSD	COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q04637	EIF4G1	P28482	MAPK1	T207	P208L	208	Missense	proximal	1	no	15.634	6.824	EPSD	COSMIC	8.102	Loss
CMGC_MAPK_ERK1_MAPK1_ST	Q04637	EIF4G1	P28482	MAPK1	T207	S204T	204	Missense	distal	-3	no	15.634	15.601	EPSD	COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q04637	EIF4G1	P28482	MAPK1	T207	G214S	214	Missense	distal	7	no	15.634	15.565	EPSD	COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q04637	EIF4G1	P28482	MAPK1	T207	R201C	201	Missense	distal	-6	no	15.634	15.459	EPSD	COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q04637	EIF4G1	P28482	MAPK1	T207	R201H	201	Missense	distal	-6	no	15.634	15.551	EPSD	COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q04637	EIF4G1	P28482	MAPK1	T207	T211M	211	Missense	distal	4	no	15.634	15.559	EPSD	COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q04637	EIF4G1	P28482	MAPK1	T223	G221S	221	Missense	proximal	-2	no	11.233	11.592	EPSD	COSMIC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q04637	EIF4G1	P28482	MAPK1	T223	I229N	229	Missense	distal	6	no	11.233	11.804	EPSD	COSMIC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q04637	EIF4G1	P28482	MAPK1	T223	T223M	223	Missense	central	0	yes	11.233	0.000	EPSD	COSMIC	8.102	Loss
CMGC_MAPK_ERK1_MAPK1_ST	Q04637	EIF4G1	P28482	MAPK1	S253	E256K	256	Missense	distal	3	no	13.564	13.571	EPSD	COSMIC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q04637	EIF4G1	P28482	MAPK1	S253	P250S	250	Missense	distal	-3	no	13.564	13.388	EPSD	COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q04637	EIF4G1	P28482	MAPK1	S253	S260L	260	Missense	distal	7	no	13.564	13.853	EPSD	COSMIC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q04637	EIF4G1	P28482	MAPK1	S253	G249C	249	Missense	distal	-4	no	13.564	13.187	EPSD	COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q04637	EIF4G1	P28482	MAPK1	S253	P248S	248	Missense	distal	-5	no	13.564	13.638	EPSD	COSMIC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q04637	EIF4G1	P28482	MAPK1	S253	S255L	255	Missense	proximal	2	no	13.564	13.445	EPSD	COSMIC;GDSC;CCLE	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q04637	EIF4G1	P28482	MAPK1	S257	S255L	255	Missense	proximal	-2	no	7.199	8.116	EPSD	COSMIC;GDSC;CCLE	8.102	Gain
CMGC_MAPK_ERK1_MAPK1_ST	Q04637	EIF4G1	P28482	MAPK1	S261	E256K	256	Missense	distal	-5	no	16.539	16.517	EPSD	COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q04637	EIF4G1	P28482	MAPK1	S261	T265K	265	Missense	distal	4	no	16.539	16.639	EPSD	COSMIC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q04637	EIF4G1	P28482	MAPK1	S261	S260L	260	Missense	proximal	-1	no	16.539	16.523	EPSD	COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q04637	EIF4G1	P28482	MAPK1	S261	P264S	264	Missense	distal	3	no	16.539	16.608	EPSD	COSMIC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q04637	EIF4G1	P28482	MAPK1	S261	P266S	266	Missense	distal	5	no	16.539	16.557	EPSD	COSMIC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q04637	EIF4G1	P28482	MAPK1	S261	S255L	255	Missense	distal	-6	no	16.539	16.473	EPSD	COSMIC;GDSC;CCLE	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q04637	EIF4G1	P28482	MAPK1	S263	P270S	270	Missense	distal	7	no	14.971	14.982	EPSD	COSMIC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q04637	EIF4G1	P28482	MAPK1	S263	E256K	256	Missense	distal	-7	no	14.971	14.964	EPSD	COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q04637	EIF4G1	P28482	MAPK1	S263	T265K	265	Missense	proximal	2	no	14.971	14.954	EPSD	COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q04637	EIF4G1	P28482	MAPK1	S263	S260L	260	Missense	distal	-3	no	14.971	14.763	EPSD	COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q04637	EIF4G1	P28482	MAPK1	S263	S269Y	269	Missense	distal	6	no	14.971	14.352	EPSD	COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q04637	EIF4G1	P28482	MAPK1	S263	P264S	264	Missense	proximal	1	no	14.971	5.576	EPSD	COSMIC	8.102	Loss
CMGC_MAPK_ERK1_MAPK1_ST	Q04637	EIF4G1	P28482	MAPK1	S263	P266S	266	Missense	distal	3	no	14.971	15.040	EPSD	COSMIC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q04637	EIF4G1	P28482	MAPK1	S263	S269F	269	Missense	distal	6	no	14.971	14.530	EPSD	COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q04637	EIF4G1	P28482	MAPK1	T265	P270S	270	Missense	distal	5	no	14.574	14.592	EPSD	COSMIC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q04637	EIF4G1	P28482	MAPK1	T265	T265K	265	Missense	central	0	yes	14.574	0.000	EPSD	COSMIC	8.102	Loss
CMGC_MAPK_ERK1_MAPK1_ST	Q04637	EIF4G1	P28482	MAPK1	T265	S260L	260	Missense	distal	-5	no	14.574	14.648	EPSD	COSMIC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q04637	EIF4G1	P28482	MAPK1	T265	S269Y	269	Missense	distal	4	no	14.574	14.379	EPSD	COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q04637	EIF4G1	P28482	MAPK1	T265	P264S	264	Missense	proximal	-1	no	14.574	14.530	EPSD	COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q04637	EIF4G1	P28482	MAPK1	T265	P266S	266	Missense	proximal	1	no	14.574	5.179	EPSD	COSMIC	8.102	Loss
CMGC_MAPK_ERK1_MAPK1_ST	Q04637	EIF4G1	P28482	MAPK1	T265	S269F	269	Missense	distal	4	no	14.574	14.396	EPSD	COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q04637	EIF4G1	P28482	MAPK1	S267	P270S	270	Missense	distal	3	no	13.257	13.327	EPSD	COSMIC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q04637	EIF4G1	P28482	MAPK1	S267	T265K	265	Missense	proximal	-2	no	13.257	13.537	EPSD	COSMIC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q04637	EIF4G1	P28482	MAPK1	S267	P274S	274	Missense	distal	7	no	13.257	13.268	EPSD	COSMIC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q04637	EIF4G1	P28482	MAPK1	S267	S260L	260	Missense	distal	-7	no	13.257	13.250	EPSD	COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q04637	EIF4G1	P28482	MAPK1	S267	S269Y	269	Missense	proximal	2	no	13.257	13.090	EPSD	COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q04637	EIF4G1	P28482	MAPK1	S267	P264S	264	Missense	distal	-3	no	13.257	13.081	EPSD	COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q04637	EIF4G1	P28482	MAPK1	S267	P266S	266	Missense	proximal	-1	no	13.257	13.214	EPSD	COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q04637	EIF4G1	P28482	MAPK1	S267	S269F	269	Missense	proximal	2	no	13.257	13.126	EPSD	COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q04637	EIF4G1	P28482	MAPK1	S269	S276Y	276	Missense	distal	7	no	14.135	14.652	EPSD	COSMIC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q04637	EIF4G1	P28482	MAPK1	S269	S276F	276	Missense	distal	7	no	14.135	14.482	EPSD	COSMIC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q04637	EIF4G1	P28482	MAPK1	S269	P270S	270	Missense	proximal	1	no	14.135	4.740	EPSD	COSMIC	8.102	Loss
CMGC_MAPK_ERK1_MAPK1_ST	Q04637	EIF4G1	P28482	MAPK1	S269	T265K	265	Missense	distal	-4	no	14.135	14.437	EPSD	COSMIC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q04637	EIF4G1	P28482	MAPK1	S269	P274S	274	Missense	distal	5	no	14.135	14.153	EPSD	COSMIC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q04637	EIF4G1	P28482	MAPK1	S269	S269Y	269	Missense	central	0	yes	14.135	0.000	EPSD	COSMIC	8.102	Loss
CMGC_MAPK_ERK1_MAPK1_ST	Q04637	EIF4G1	P28482	MAPK1	S269	P264S	264	Missense	distal	-5	no	14.135	14.209	EPSD	COSMIC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q04637	EIF4G1	P28482	MAPK1	S269	P266S	266	Missense	distal	-3	no	14.135	13.958	EPSD	COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q04637	EIF4G1	P28482	MAPK1	S269	S269F	269	Missense	central	0	yes	14.135	0.000	EPSD	COSMIC	8.102	Loss
CMGC_MAPK_ERK1_MAPK1_ST	Q04637	EIF4G1	P28482	MAPK1	T301	E306D	306	Missense	distal	5	no	13.460	13.530	EPSD	COSMIC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q04637	EIF4G1	P28482	MAPK1	T301	E298D	298	Missense	distal	-3	no	13.460	13.512	EPSD	COSMIC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q04637	EIF4G1	P28482	MAPK1	T301	E299D	299	Missense	proximal	-2	no	13.460	12.538	EPSD	COSMIC;GDSC;CCLE	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q04637	EIF4G1	P28482	MAPK1	T301	S300L	300	Missense	proximal	-1	no	13.460	13.444	EPSD	COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q04637	EIF4G1	P28482	MAPK1	S314	P315S	315	Missense	proximal	1	no	13.497	4.102	EPSD	COSMIC	8.102	Loss
CMGC_MAPK_ERK1_MAPK1_ST	Q04637	EIF4G1	P28482	MAPK1	S314	R312H	312	Missense	proximal	-2	no	13.497	12.560	EPSD	COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q04637	EIF4G1	P28482	MAPK1	T318	E322K	322	Missense	distal	4	no	13.616	13.630	EPSD	COSMIC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q04637	EIF4G1	P28482	MAPK1	T318	P315S	315	Missense	distal	-3	no	13.616	13.439	EPSD	COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q04637	EIF4G1	P28482	MAPK1	T318	R312H	312	Missense	distal	-6	no	13.616	13.533	EPSD	COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q04637	EIF4G1	P28482	MAPK1	S343	P350L	350	Missense	distal	7	no	14.619	14.919	EPSD	COSMIC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q04637	EIF4G1	P28482	MAPK1	S343	P350H	350	Missense	distal	7	no	14.619	14.853	EPSD	COSMIC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q04637	EIF4G1	P28482	MAPK1	S343	S341Y	341	Missense	proximal	-2	no	14.619	15.336	EPSD	COSMIC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q04637	EIF4G1	P28482	MAPK1	S343	L345F	345	Missense	proximal	2	no	14.619	14.607	EPSD	COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q04637	EIF4G1	P28482	MAPK1	S343	P344S	344	Missense	proximal	1	no	14.619	5.224	EPSD	COSMIC	8.102	Loss
CMGC_MAPK_ERK1_MAPK1_ST	Q04637	EIF4G1	P28482	MAPK1	T349	P350L	350	Missense	proximal	1	no	12.170	3.360	EPSD	COSMIC	8.102	Loss
CMGC_MAPK_ERK1_MAPK1_ST	Q04637	EIF4G1	P28482	MAPK1	T349	P350H	350	Missense	proximal	1	no	12.170	4.346	EPSD	COSMIC	8.102	Loss
CMGC_MAPK_ERK1_MAPK1_ST	Q04637	EIF4G1	P28482	MAPK1	T349	S353C	353	Missense	distal	4	no	12.170	11.888	EPSD	COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q04637	EIF4G1	P28482	MAPK1	T349	L345F	345	Missense	distal	-4	no	12.170	12.130	EPSD	COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q04637	EIF4G1	P28482	MAPK1	T349	P344S	344	Missense	distal	-5	no	12.170	12.244	EPSD	COSMIC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q04637	EIF4G1	P28482	MAPK1	S409	S416L	416	Missense	distal	7	no	11.954	12.242	EPSD	COSMIC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q04637	EIF4G1	P28482	MAPK1	S409	D414N	414	Missense	distal	5	no	11.954	11.856	EPSD	COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q04637	EIF4G1	P28482	MAPK1	S409	P408S	408	Missense	proximal	-1	no	11.954	11.911	EPSD	COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q04637	EIF4G1	P28482	MAPK1	S409	G406V	406	Missense	distal	-3	no	11.954	11.836	EPSD	COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q04637	EIF4G1	P28482	MAPK1	S409	L404F	404	Missense	distal	-5	no	11.954	11.968	EPSD	COSMIC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q04637	EIF4G1	P28482	MAPK1	S409	A407D	407	Missense	proximal	-2	no	11.954	11.799	EPSD	COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q04637	EIF4G1	P28482	MAPK1	S409	S409L	409	Missense	central	0	yes	11.954	0.000	EPSD	COSMIC	8.102	Loss
CMGC_MAPK_ERK1_MAPK1_ST	Q04637	EIF4G1	P28482	MAPK1	S409	A412S	412	Missense	distal	3	no	11.954	11.945	EPSD	COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q04637	EIF4G1	P28482	MAPK1	S416	S416L	416	Missense	central	0	yes	13.619	0.000	EPSD	COSMIC	8.102	Loss
CMGC_MAPK_ERK1_MAPK1_ST	Q04637	EIF4G1	P28482	MAPK1	S416	D414N	414	Missense	proximal	-2	no	13.619	14.100	EPSD	COSMIC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q04637	EIF4G1	P28482	MAPK1	S416	E422Q	422	Missense	distal	6	no	13.619	13.297	EPSD	COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q04637	EIF4G1	P28482	MAPK1	S416	S409L	409	Missense	distal	-7	no	13.619	13.611	EPSD	COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q04637	EIF4G1	P28482	MAPK1	S416	A412S	412	Missense	distal	-4	no	13.619	13.828	EPSD	COSMIC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q04637	EIF4G1	P28482	MAPK1	T441	A440V	440	Missense	proximal	-1	no	12.286	12.297	EPSD	COSMIC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q04637	EIF4G1	P28482	MAPK1	T441	T436K	436	Missense	distal	-5	no	12.286	12.185	EPSD	COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q04637	EIF4G1	P28482	MAPK1	T441	P434L	434	Missense	distal	-7	no	12.286	12.273	EPSD	COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q04637	EIF4G1	P28482	MAPK1	T441	T444M	444	Missense	distal	3	no	12.286	12.309	EPSD	COSMIC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q04637	EIF4G1	P28482	MAPK1	T441	P434S	434	Missense	distal	-7	no	12.286	12.281	EPSD	COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q04637	EIF4G1	P28482	MAPK1	T441	S439F	439	Missense	proximal	-2	no	12.286	12.479	EPSD	COSMIC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q04637	EIF4G1	P28482	MAPK1	T441	P446S	446	Missense	distal	5	no	12.286	12.304	EPSD	COSMIC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q04637	EIF4G1	P28482	MAPK1	T444	S439F	439	Missense	distal	-5	no	8.044	8.132	EPSD	COSMIC	8.102	Gain
CMGC_MAPK_ERK1_MAPK1_ST	Q04637	EIF4G1	P28482	MAPK1	S450	M457I	457	Missense	distal	7	no	13.151	13.339	EPSD	COSMIC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q04637	EIF4G1	P28482	MAPK1	S450	M457V	457	Missense	distal	7	no	13.151	13.074	EPSD	COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q04637	EIF4G1	P28482	MAPK1	S450	E455D	455	Missense	distal	5	no	13.151	13.220	EPSD	COSMIC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q04637	EIF4G1	P28482	MAPK1	S450	T444M	444	Missense	distal	-6	no	13.151	13.116	EPSD	COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q04637	EIF4G1	P28482	MAPK1	S450	A452S	452	Missense	proximal	2	no	13.151	13.252	EPSD	COSMIC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q04637	EIF4G1	P28482	MAPK1	S450	P446S	446	Missense	distal	-4	no	13.151	13.067	EPSD	COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q04637	EIF4G1	P28482	MAPK1	S450	S450F	450	Missense	central	0	yes	13.151	0.000	EPSD	COSMIC	8.102	Loss
CMGC_MAPK_ERK1_MAPK1_ST	Q04637	EIF4G1	P28482	MAPK1	S450	E456G	456	Missense	distal	6	no	13.151	13.040	EPSD	COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q04637	EIF4G1	P28482	MAPK1	S488	A493T	493	Missense	distal	5	no	9.515	9.601	EPSD	COSMIC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q04637	EIF4G1	P28482	MAPK1	S488	I491T	491	Missense	distal	3	no	9.515	9.449	EPSD	COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q04637	EIF4G1	P28482	MAPK1	S488	E481Q	481	Missense	distal	-7	no	9.515	9.513	EPSD	COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q04637	EIF4G1	P28482	MAPK1	S488	P492Q	492	Missense	distal	4	no	9.515	9.407	EPSD	COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q04637	EIF4G1	P28482	MAPK1	T489	A493T	493	Missense	distal	4	no	12.777	12.757	EPSD	COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q04637	EIF4G1	P28482	MAPK1	T489	I491T	491	Missense	proximal	2	no	12.777	12.897	EPSD	COSMIC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q04637	EIF4G1	P28482	MAPK1	T489	P492Q	492	Missense	distal	3	no	12.777	12.845	EPSD	COSMIC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q04637	EIF4G1	P28482	MAPK1	T647	R650W	650	Missense	distal	3	no	13.241	13.391	EPSD	COSMIC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q04637	EIF4G1	P28482	MAPK1	T647	K643R	643	Missense	distal	-4	no	13.241	13.163	EPSD	COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q04637	EIF4G1	P28482	MAPK1	T647	K643T	643	Missense	distal	-4	no	13.241	12.939	EPSD	COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q04637	EIF4G1	P28482	MAPK1	T647	K643N	643	Missense	distal	-4	no	13.241	13.209	EPSD	COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q04637	EIF4G1	P28482	MAPK1	T647	K643M	643	Missense	distal	-4	no	13.241	12.786	EPSD	COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q04637	EIF4G1	P28482	MAPK1	T647	R650Q	650	Missense	distal	3	no	13.241	13.263	EPSD	COSMIC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q04637	EIF4G1	P28482	MAPK1	T667	N661H	661	Missense	distal	-6	no	13.511	13.459	EPSD	COSMIC;GDSC;CCLE	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q04637	EIF4G1	P28482	MAPK1	T667	D665Y	665	Missense	proximal	-2	no	13.511	14.695	EPSD	COSMIC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q04637	EIF4G1	P28482	MAPK1	T667	P668A	668	Missense	proximal	1	no	13.511	5.881	EPSD	COSMIC	8.102	Loss
CMGC_MAPK_ERK1_MAPK1_ST	Q04637	EIF4G1	P28482	MAPK1	T667	P668L	668	Missense	proximal	1	no	13.511	4.701	EPSD	COSMIC	8.102	Loss
CMGC_MAPK_ERK1_MAPK1_ST	Q04637	EIF4G1	P28482	MAPK1	T667	D665N	665	Missense	proximal	-2	no	13.511	13.993	EPSD	COSMIC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q04637	EIF4G1	P28482	MAPK1	T667	P668Q	668	Missense	proximal	1	no	13.511	5.017	EPSD	COSMIC	8.102	Loss
CMGC_MAPK_ERK1_MAPK1_ST	Q04637	EIF4G1	P28482	MAPK1	T667	P664T	664	Missense	distal	-3	no	13.511	13.302	EPSD	COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q04637	EIF4G1	P28482	MAPK1	S669	P664T	664	Missense	distal	-5	no	8.049	8.152	EPSD	COSMIC	8.102	Gain
CMGC_MAPK_ERK1_MAPK1_ST	Q04637	EIF4G1	P28482	MAPK1	S895	L896P	896	Missense	proximal	1	no	6.232	15.042	EPSD	COSMIC	8.102	Gain
CMGC_MAPK_ERK1_MAPK1_ST	Q04637	EIF4G1	P28482	MAPK1	S1041	R1042H	1042	Missense	proximal	1	no	6.482	8.313	EPSD	COSMIC	8.102	Gain
CMGC_MAPK_ERK1_MAPK1_ST	Q04637	EIF4G1	P28482	MAPK1	T1066	S1067P	1067	Missense	proximal	1	no	5.076	14.471	EPSD	COSMIC	8.102	Gain
CMGC_MAPK_ERK1_MAPK1_ST	Q04637	EIF4G1	P28482	MAPK1	S1092	L1091R	1091	Missense	proximal	-1	no	8.122	8.162	EPSD	COSMIC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q04637	EIF4G1	P28482	MAPK1	S1092	G1089W	1089	Missense	distal	-3	no	8.122	7.592	EPSD	COSMIC	8.102	Loss
CMGC_MAPK_ERK1_MAPK1_ST	Q04637	EIF4G1	P28482	MAPK1	S1092	G1096D	1096	Missense	distal	4	no	8.122	8.074	EPSD	COSMIC	8.102	Loss
CMGC_MAPK_ERK1_MAPK1_ST	Q04637	EIF4G1	P28482	MAPK1	S1092	P1087S	1087	Missense	distal	-5	no	8.122	8.196	EPSD	COSMIC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q04637	EIF4G1	P28482	MAPK1	S1092	S1097I	1097	Missense	distal	5	no	8.122	7.805	EPSD	COSMIC	8.102	Loss
CMGC_MAPK_ERK1_MAPK1_ST	Q04637	EIF4G1	P28482	MAPK1	S1092	S1098I	1098	Missense	distal	6	no	8.122	7.455	EPSD	COSMIC	8.102	Loss
CMGC_MAPK_ERK1_MAPK1_ST	Q04637	EIF4G1	P28482	MAPK1	S1118	A1116V	1116	Missense	proximal	-2	no	8.289	9.563	EPSD	COSMIC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q04637	EIF4G1	P28482	MAPK1	S1118	T1117A	1117	Missense	proximal	-1	no	8.289	8.294	EPSD	COSMIC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q04637	EIF4G1	P28482	MAPK1	S1118	R1114H	1114	Missense	distal	-4	no	8.289	8.137	EPSD	COSMIC;CCLE	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q04637	EIF4G1	P28482	MAPK1	S1118	S1118R	1118	Missense	central	0	yes	8.289	0.000	EPSD	COSMIC	8.102	Loss
CMGC_MAPK_ERK1_MAPK1_ST	Q04637	EIF4G1	P28482	MAPK1	S1118	A1125S	1125	Missense	distal	7	no	8.289	8.108	EPSD	COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q04637	EIF4G1	P28482	MAPK1	S1118	R1122H	1122	Missense	distal	4	no	8.289	8.148	EPSD	COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q04637	EIF4G1	P28482	MAPK1	S1118	R1114S	1114	Missense	distal	-4	no	8.289	8.295	EPSD	COSMIC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q04637	EIF4G1	P28482	MAPK1	S1124	T1117A	1117	Missense	distal	-7	no	8.277	8.291	EPSD	COSMIC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q04637	EIF4G1	P28482	MAPK1	S1124	S1118R	1118	Missense	distal	-6	no	8.277	8.311	EPSD	COSMIC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q04637	EIF4G1	P28482	MAPK1	S1124	A1125S	1125	Missense	proximal	1	no	8.277	6.512	EPSD	COSMIC	8.102	Loss
CMGC_MAPK_ERK1_MAPK1_ST	Q04637	EIF4G1	P28482	MAPK1	S1124	R1122H	1122	Missense	proximal	-2	no	8.277	7.340	EPSD	COSMIC	8.102	Loss
CMGC_MAPK_ERK1_MAPK1_ST	Q04637	EIF4G1	P28482	MAPK1	S1124	A1129V	1129	Missense	distal	5	no	8.277	8.294	EPSD	COSMIC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q04637	EIF4G1	P28482	MAPK1	T1179	R1173W	1173	Missense	distal	-6	no	14.265	14.045	EPSD	COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q04637	EIF4G1	P28482	MAPK1	T1179	T1182I	1182	Missense	distal	3	no	14.265	14.331	EPSD	COSMIC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q04637	EIF4G1	P28482	MAPK1	T1179	A1177G	1177	Missense	proximal	-2	no	14.265	14.217	EPSD	COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q04637	EIF4G1	P28482	MAPK1	T1179	D1175Y	1175	Missense	distal	-4	no	14.265	13.606	EPSD	COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q04637	EIF4G1	P28482	MAPK1	T1179	A1177V	1177	Missense	proximal	-2	no	14.265	15.539	EPSD	COSMIC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q04637	EIF4G1	P28482	MAPK1	T1179	R1176C	1176	Missense	distal	-3	no	14.265	13.581	EPSD	COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q04637	EIF4G1	P28482	MAPK1	T1179	R1178W	1178	Missense	proximal	-1	no	14.265	14.164	EPSD	COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q04637	EIF4G1	P28482	MAPK1	T1179	L1174F	1174	Missense	distal	-5	no	14.265	14.278	EPSD	COSMIC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q04637	EIF4G1	P28482	MAPK1	S1185	T1182I	1182	Missense	distal	-3	no	8.221	7.989	EPSD	COSMIC	8.102	Loss
CMGC_MAPK_ERK1_MAPK1_ST	Q04637	EIF4G1	P28482	MAPK1	S1185	E1191D	1191	Missense	distal	6	no	8.221	8.142	EPSD	COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q04637	EIF4G1	P28482	MAPK1	S1185	R1178W	1178	Missense	distal	-7	no	8.221	8.170	EPSD	COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q04637	EIF4G1	P28482	MAPK1	S1185	S1187F	1187	Missense	proximal	2	no	8.221	8.089	EPSD	COSMIC	8.102	Loss
CMGC_MAPK_ERK1_MAPK1_ST	Q04637	EIF4G1	P28482	MAPK1	S1185	S1187P	1187	Missense	proximal	2	no	8.221	8.249	EPSD	COSMIC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q04637	EIF4G1	P28482	MAPK1	S1185	E1192D	1192	Missense	distal	7	no	8.221	8.276	EPSD	COSMIC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q04637	EIF4G1	P28482	MAPK1	S1231	A1236V	1236	Missense	distal	5	no	16.580	16.597	EPSD	COSMIC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q04637	EIF4G1	P28482	MAPK1	S1231	A1226D	1226	Missense	distal	-5	no	16.580	16.525	EPSD	COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q04637	EIF4G1	P28482	MAPK1	S1231	A1225S	1225	Missense	distal	-6	no	16.580	16.593	EPSD	COSMIC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q04637	EIF4G1	P28482	MAPK1	S1231	A1236T	1236	Missense	distal	5	no	16.580	16.666	EPSD	COSMIC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q04637	EIF4G1	P28482	MAPK1	S1231	S1238C	1238	Missense	distal	7	no	16.580	17.239	EPSD	COSMIC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q04637	EIF4G1	P28482	MAPK1	S1231	A1235V	1235	Missense	distal	4	no	16.580	16.574	EPSD	COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q04637	EIF4G1	P28482	MAPK1	S1231	A1226S	1226	Missense	distal	-5	no	16.580	16.529	EPSD	COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q04637	EIF4G1	P28482	MAPK1	S1271	I1277F	1277	Missense	distal	6	no	13.949	14.175	EPSD	COSMIC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q04637	EIF4G1	P28482	MAPK1	S1271	S1273F	1273	Missense	proximal	2	no	13.949	13.817	EPSD	COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q04637	EIF4G1	P28482	MAPK1	S1271	V1266M	1266	Missense	distal	-5	no	13.949	14.005	EPSD	COSMIC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q04637	EIF4G1	P28482	MAPK1	S1271	L1275F	1275	Missense	distal	4	no	13.949	13.881	EPSD	COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q04637	EIF4G1	P28482	MAPK1	S1271	A1270T	1270	Missense	proximal	-1	no	13.949	13.943	EPSD	COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q04637	EIF4G1	P28482	MAPK1	S1271	S1273P	1273	Missense	proximal	2	no	13.949	13.977	EPSD	COSMIC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q04637	EIF4G1	P28482	MAPK1	T1495	I1491V	1491	Missense	distal	-4	no	12.289	12.606	EPSD	COSMIC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q04637	EIF4G1	P28482	MAPK1	T1495	P1496L	1496	Missense	proximal	1	no	12.289	3.479	EPSD	COSMIC	8.102	Loss
CMGC_MAPK_ERK1_MAPK1_ST	Q04637	EIF4G1	P28482	MAPK1	T1495	I1491T	1491	Missense	distal	-4	no	12.289	12.646	EPSD	COSMIC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q04637	EIF4G1	P28482	MAPK1	T1495	I1491N	1491	Missense	distal	-4	no	12.289	12.917	EPSD	COSMIC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q04637	EIF4G1	P28482	MAPK1	T1495	D1500G	1500	Missense	distal	5	no	12.289	12.244	EPSD	COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q04637	EIF4G1	P28482	MAPK1	T1495	I1492N	1492	Missense	distal	-3	no	12.289	12.569	EPSD	COSMIC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q04637	EIF4G1	P28482	MAPK1	T1495	I1492T	1492	Missense	distal	-3	no	12.289	12.521	EPSD	COSMIC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q04637	EIF4G1	P28482	MAPK1	T1495	I1492V	1492	Missense	distal	-3	no	12.289	12.423	EPSD	COSMIC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q04637	EIF4G1	P28482	MAPK1	T1495	T1495N	1495	Missense	central	0	yes	12.289	0.000	EPSD	COSMIC	8.102	Loss
CMGC_MAPK_ERK1_MAPK1_ST	Q13586	STIM1	P28482	MAPK1	S486	M480I	480	Missense	distal	-6	no	14.681	14.637	EPSD	COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q13586	STIM1	P28482	MAPK1	S492	Q496H	496	Missense	distal	4	no	13.552	13.485	EPSD	COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q13586	STIM1	P28482	MAPK1	S492	S494C	494	Missense	proximal	2	no	13.552	13.320	EPSD	COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q13586	STIM1	P28482	MAPK1	S575	K580N	580	Missense	distal	5	no	17.019	17.050	EPSD;PhosphoSitePlus	COSMIC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q13586	STIM1	P28482	MAPK1	S600	L599M	599	Missense	proximal	-1	no	14.780	14.790	EPSD	COSMIC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q13586	STIM1	P28482	MAPK1	S600	A593S	593	Missense	distal	-7	no	14.780	14.779	EPSD	COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q13586	STIM1	P28482	MAPK1	S608	P609L	609	Missense	proximal	1	no	14.620	5.810	PhosphoSitePlus;EPSD	COSMIC	8.102	Loss
CMGC_MAPK_ERK1_MAPK1_ST	Q13586	STIM1	P28482	MAPK1	S608	R615H	615	Missense	distal	7	no	14.620	14.839	PhosphoSitePlus;EPSD	COSMIC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q13586	STIM1	P28482	MAPK1	S618	S616L	616	Missense	proximal	-2	no	15.649	16.566	EPSD	COSMIC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q13586	STIM1	P28482	MAPK1	S618	P622Q	622	Missense	distal	4	no	15.649	15.541	EPSD	COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q13586	STIM1	P28482	MAPK1	S618	P619L	619	Missense	proximal	1	no	15.649	6.840	EPSD	COSMIC;GDSC;CCLE	8.102	Loss
CMGC_MAPK_ERK1_MAPK1_ST	Q13586	STIM1	P28482	MAPK1	S618	R615H	615	Missense	distal	-3	no	15.649	15.319	EPSD	COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q13586	STIM1	P28482	MAPK1	S621	S616L	616	Missense	distal	-5	no	17.201	17.275	EPSD;PhosphoSitePlus	COSMIC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q13586	STIM1	P28482	MAPK1	S621	P622Q	622	Missense	proximal	1	no	17.201	8.707	EPSD;PhosphoSitePlus	COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q13586	STIM1	P28482	MAPK1	S621	P619L	619	Missense	proximal	-2	no	17.201	15.283	EPSD;PhosphoSitePlus	COSMIC;GDSC;CCLE	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q13586	STIM1	P28482	MAPK1	S621	R615H	615	Missense	distal	-6	no	17.201	17.118	EPSD;PhosphoSitePlus	COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q13586	STIM1	P28482	MAPK1	T626	P622Q	622	Missense	distal	-4	no	15.638	15.445	EPSD	COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q13586	STIM1	P28482	MAPK1	T626	V630A	630	Missense	distal	4	no	15.638	15.644	EPSD	COSMIC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q13586	STIM1	P28482	MAPK1	T626	P619L	619	Missense	distal	-7	no	15.638	15.626	EPSD	COSMIC;GDSC;CCLE	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q13586	STIM1	P28482	MAPK1	S628	P622Q	622	Missense	distal	-6	no	15.060	15.045	EPSD	COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q13586	STIM1	P28482	MAPK1	S628	V630A	630	Missense	proximal	2	no	15.060	14.984	EPSD	COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q13586	STIM1	P28482	MAPK1	S668	R671Q	671	Missense	distal	3	no	16.481	16.503	EPSD	COSMIC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q13586	STIM1	P28482	MAPK1	S668	S667C	667	Missense	proximal	-1	no	16.481	16.403	EPSD	COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q13586	STIM1	P28482	MAPK1	S668	P669Q	669	Missense	proximal	1	no	16.481	7.987	EPSD	COSMIC	8.102	Loss
CMGC_MAPK_ERK1_MAPK1_ST	Q02224	CENPE	P28482	MAPK1	S130	V129A	129	Missense	proximal	-1	no	8.500	8.489	EPSD	COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q02224	CENPE	P28482	MAPK1	S130	E133Q	133	Missense	distal	3	no	8.500	8.577	EPSD	COSMIC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q02224	CENPE	P28482	MAPK1	S1745	S1752L	1752	Missense	distal	7	no	7.919	8.208	EPSD	COSMIC	8.102	Gain
CMGC_MAPK_ERK1_MAPK1_ST	Q02224	CENPE	P28482	MAPK1	T2622	K2618N	2618	Missense	distal	-4	no	13.092	13.060	EPSD	COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q02224	CENPE	P28482	MAPK1	S2654	R2648Q	2648	Missense	distal	-6	no	13.737	13.714	EPSD;PhosphoSitePlus	COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P50616	TOB1	P28482	MAPK1	S14	F11C	11	Missense	distal	-3	no	9.345	9.051	EPSD	COSMIC;GDSC;CCLE	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P50616	TOB1	P28482	MAPK1	S143	D144N	144	Missense	proximal	1	no	9.563	-1.464	EPSD	COSMIC	8.102	Loss
CMGC_MAPK_ERK1_MAPK1_ST	P50616	TOB1	P28482	MAPK1	S147	D144N	144	Missense	distal	-3	no	8.397	8.365	EPSD	COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P50616	TOB1	P28482	MAPK1	S164	T166I	166	Missense	proximal	2	no	14.103	13.982	EPSD;PhosphoSitePlus	COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P50616	TOB1	P28482	MAPK1	S164	R170W	170	Missense	distal	6	no	14.103	13.180	EPSD;PhosphoSitePlus	COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P50616	TOB1	P28482	MAPK1	S205	L211F	211	Missense	distal	6	no	14.727	14.692	EPSD	COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P50616	TOB1	P28482	MAPK1	S268	P269A	269	Missense	proximal	1	no	14.102	6.472	EPSD	COSMIC	8.102	Loss
CMGC_MAPK_ERK1_MAPK1_ST	P50616	TOB1	P28482	MAPK1	S268	L267F	267	Missense	proximal	-1	no	14.102	14.072	EPSD	COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P49815	TSC2	P28482	MAPK1	T23	I17N	17	Missense	distal	-6	no	16.713	16.818	EPSD	COSMIC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P49815	TSC2	P28482	MAPK1	T23	G22R	22	Missense	proximal	-1	no	16.713	16.748	EPSD	COSMIC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P49815	TSC2	P28482	MAPK1	T23	G20E	20	Missense	distal	-3	no	16.713	16.722	EPSD	COSMIC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P49815	TSC2	P28482	MAPK1	S30	E32D	32	Missense	proximal	2	no	10.401	10.453	EPSD	COSMIC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P49815	TSC2	P28482	MAPK1	S30	G33R	33	Missense	distal	3	no	10.401	10.364	EPSD	COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P49815	TSC2	P28482	MAPK1	S540	S540F	540	Missense	central	0	yes	13.757	0.000	EPSD	COSMIC	8.102	Loss
CMGC_MAPK_ERK1_MAPK1_ST	P49815	TSC2	P28482	MAPK1	S540	P542L	542	Missense	proximal	2	no	13.757	13.610	EPSD	COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P49815	TSC2	P28482	MAPK1	S540	S538P	538	Missense	proximal	-2	no	13.757	16.592	EPSD	COSMIC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P49815	TSC2	P28482	MAPK1	S540	L539F	539	Missense	proximal	-1	no	13.757	13.728	EPSD	COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P49815	TSC2	P28482	MAPK1	S540	P543Q	543	Missense	distal	3	no	13.757	13.825	EPSD	COSMIC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P49815	TSC2	P28482	MAPK1	S664	P665F	665	Missense	proximal	1	no	17.995	11.425	PhosphoSitePlus	COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P49815	TSC2	P28482	MAPK1	S664	P665S	665	Missense	proximal	1	no	17.995	8.600	PhosphoSitePlus	COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P49815	TSC2	P28482	MAPK1	S664	P666S	666	Missense	proximal	2	no	17.995	17.967	PhosphoSitePlus	COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P49815	TSC2	P28482	MAPK1	S923	D925Y	925	Missense	proximal	2	no	8.522	8.342	EPSD	COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P49815	TSC2	P28482	MAPK1	S923	S918F	918	Missense	distal	-5	no	8.522	8.610	EPSD	COSMIC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P49815	TSC2	P28482	MAPK1	S923	E929D	929	Missense	distal	6	no	8.522	8.443	EPSD	COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P49815	TSC2	P28482	MAPK1	S923	P928S	928	Missense	distal	5	no	8.522	8.540	EPSD	COSMIC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P49815	TSC2	P28482	MAPK1	S923	P928L	928	Missense	distal	5	no	8.522	8.309	EPSD	COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P49815	TSC2	P28482	MAPK1	S923	L916R	916	Missense	distal	-7	no	8.522	8.529	EPSD	COSMIC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P49815	TSC2	P28482	MAPK1	S923	D926H	926	Missense	distal	3	no	8.522	8.524	EPSD	COSMIC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P49815	TSC2	P28482	MAPK1	S923	T927I	927	Missense	distal	4	no	8.522	8.469	EPSD	COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P49815	TSC2	P28482	MAPK1	T927	D925Y	925	Missense	proximal	-2	no	13.942	15.127	EPSD	COSMIC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P49815	TSC2	P28482	MAPK1	T927	E929D	929	Missense	proximal	2	no	13.942	13.994	EPSD	COSMIC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P49815	TSC2	P28482	MAPK1	T927	P928S	928	Missense	proximal	1	no	13.942	4.548	EPSD	COSMIC	8.102	Loss
CMGC_MAPK_ERK1_MAPK1_ST	P49815	TSC2	P28482	MAPK1	T927	P928L	928	Missense	proximal	1	no	13.942	5.133	EPSD	COSMIC	8.102	Loss
CMGC_MAPK_ERK1_MAPK1_ST	P49815	TSC2	P28482	MAPK1	T927	D926H	926	Missense	proximal	-1	no	13.942	13.955	EPSD	COSMIC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P49815	TSC2	P28482	MAPK1	T927	S932N	932	Missense	distal	5	no	13.942	13.870	EPSD	COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P49815	TSC2	P28482	MAPK1	T927	T927I	927	Missense	central	0	yes	13.942	0.000	EPSD	COSMIC	8.102	Loss
CMGC_MAPK_ERK1_MAPK1_ST	P49815	TSC2	P28482	MAPK1	S932	D925Y	925	Missense	distal	-7	no	9.149	9.117	EPSD	COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P49815	TSC2	P28482	MAPK1	S932	E929D	929	Missense	distal	-3	no	9.149	9.200	EPSD	COSMIC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P49815	TSC2	P28482	MAPK1	S932	R936Q	936	Missense	distal	4	no	9.149	9.074	EPSD	COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P49815	TSC2	P28482	MAPK1	S932	P928S	928	Missense	distal	-4	no	9.149	9.065	EPSD	COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P49815	TSC2	P28482	MAPK1	S932	P928L	928	Missense	distal	-4	no	9.149	8.845	EPSD	COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P49815	TSC2	P28482	MAPK1	S932	D926H	926	Missense	distal	-6	no	9.149	9.052	EPSD	COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P49815	TSC2	P28482	MAPK1	S932	A935S	935	Missense	distal	3	no	9.149	9.140	EPSD	COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P49815	TSC2	P28482	MAPK1	S932	S932N	932	Missense	central	0	yes	9.149	0.000	EPSD	COSMIC	8.102	Loss
CMGC_MAPK_ERK1_MAPK1_ST	P49815	TSC2	P28482	MAPK1	S932	T927I	927	Missense	distal	-5	no	9.149	9.256	EPSD	COSMIC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P49815	TSC2	P28482	MAPK1	S932	T938I	938	Missense	distal	6	no	9.149	8.692	EPSD	COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P49815	TSC2	P28482	MAPK1	S946	E942K	942	Missense	distal	-4	no	8.996	9.014	EPSD	COSMIC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P49815	TSC2	P28482	MAPK1	S946	K945E	945	Missense	proximal	-1	no	8.996	8.968	EPSD	COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P49815	TSC2	P28482	MAPK1	S946	S946I	946	Missense	central	0	yes	8.996	0.000	EPSD	COSMIC	8.102	Loss
CMGC_MAPK_ERK1_MAPK1_ST	P49815	TSC2	P28482	MAPK1	S960	N958S	958	Missense	proximal	-2	no	11.546	11.532	EPSD	COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P49815	TSC2	P28482	MAPK1	S960	P962F	962	Missense	proximal	2	no	11.546	11.387	EPSD	COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P49815	TSC2	P28482	MAPK1	S960	P962S	962	Missense	proximal	2	no	11.546	11.519	EPSD	COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P49815	TSC2	P28482	MAPK1	S1002	S1002L	1002	Missense	central	0	yes	8.547	0.000	EPSD	COSMIC	8.102	Loss
CMGC_MAPK_ERK1_MAPK1_ST	P49815	TSC2	P28482	MAPK1	S1002	V1008M	1008	Missense	distal	6	no	8.547	8.328	EPSD	COSMIC;CCLE	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P49815	TSC2	P28482	MAPK1	S1002	S999T	999	Missense	distal	-3	no	8.547	8.514	EPSD	COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P49815	TSC2	P28482	MAPK1	S1002	S999L	999	Missense	distal	-3	no	8.547	8.340	EPSD	COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P49815	TSC2	P28482	MAPK1	S1002	S999P	999	Missense	distal	-3	no	8.547	8.723	EPSD	COSMIC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P49815	TSC2	P28482	MAPK1	S1045	R1044K	1044	Missense	proximal	-1	no	14.811	14.844	EPSD	COSMIC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P49815	TSC2	P28482	MAPK1	S1045	A1040T	1040	Missense	distal	-5	no	14.811	14.789	EPSD	COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P49815	TSC2	P28482	MAPK1	S1045	P1042S	1042	Missense	distal	-3	no	14.811	14.635	EPSD	COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P49815	TSC2	P28482	MAPK1	S1097	S1094L	1094	Missense	distal	-3	no	13.925	13.717	EPSD	COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P49815	TSC2	P28482	MAPK1	S1097	G1099W	1099	Missense	proximal	2	no	13.925	13.651	EPSD	COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P49815	TSC2	P28482	MAPK1	S1097	E1093K	1093	Missense	distal	-4	no	13.925	13.943	EPSD	COSMIC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P49815	TSC2	P28482	MAPK1	S1097	S1095I	1095	Missense	proximal	-2	no	13.925	14.865	EPSD	COSMIC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P49815	TSC2	P28482	MAPK1	S1097	S1097C	1097	Missense	central	0	yes	13.925	0.000	EPSD	COSMIC	8.102	Loss
CMGC_MAPK_ERK1_MAPK1_ST	P49815	TSC2	P28482	MAPK1	S1155	Q1148K	1148	Missense	distal	-7	no	14.127	14.122	EPSD	COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P49815	TSC2	P28482	MAPK1	S1155	R1159Q	1159	Missense	distal	4	no	14.127	14.052	EPSD	COSMIC;GDSC;CCLE	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P49815	TSC2	P28482	MAPK1	S1155	G1151C	1151	Missense	distal	-4	no	14.127	13.750	EPSD	COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P49815	TSC2	P28482	MAPK1	S1155	S1155F	1155	Missense	central	0	yes	14.127	0.000	EPSD	COSMIC	8.102	Loss
CMGC_MAPK_ERK1_MAPK1_ST	P49815	TSC2	P28482	MAPK1	S1155	S1152P	1152	Missense	distal	-3	no	14.127	14.304	EPSD	COSMIC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P49815	TSC2	P28482	MAPK1	S1155	S1152C	1152	Missense	distal	-3	no	14.127	13.600	EPSD	COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P49815	TSC2	P28482	MAPK1	S1274	L1278M	1278	Missense	distal	4	no	9.069	8.991	EPSD	COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P49815	TSC2	P28482	MAPK1	S1274	S1274P	1274	Missense	central	0	yes	9.069	0.000	EPSD	COSMIC	8.102	Loss
CMGC_MAPK_ERK1_MAPK1_ST	P49815	TSC2	P28482	MAPK1	S1274	A1273V	1273	Missense	proximal	-1	no	9.069	9.080	EPSD	COSMIC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P49815	TSC2	P28482	MAPK1	S1274	R1268G	1268	Missense	distal	-6	no	9.069	9.018	EPSD	COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P49815	TSC2	P28482	MAPK1	S1274	S1276L	1276	Missense	proximal	2	no	9.069	8.949	EPSD	COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P49815	TSC2	P28482	MAPK1	S1274	S1274N	1274	Missense	central	0	yes	9.069	0.000	EPSD	COSMIC	8.102	Loss
CMGC_MAPK_ERK1_MAPK1_ST	P49815	TSC2	P28482	MAPK1	S1274	S1269L	1269	Missense	distal	-5	no	9.069	9.144	EPSD	COSMIC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P49815	TSC2	P28482	MAPK1	S1304	E1301D	1301	Missense	distal	-3	no	15.312	15.364	EPSD	COSMIC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P49815	TSC2	P28482	MAPK1	S1304	E1307K	1307	Missense	distal	3	no	15.312	15.319	EPSD	COSMIC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P49815	TSC2	P28482	MAPK1	S1304	P1309S	1309	Missense	distal	5	no	15.312	15.330	EPSD	COSMIC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P49815	TSC2	P28482	MAPK1	S1304	V1298M	1298	Missense	distal	-6	no	15.312	15.315	EPSD	COSMIC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P49815	TSC2	P28482	MAPK1	S1304	P1305L	1305	Missense	proximal	1	no	15.312	6.503	EPSD	COSMIC;GDSC	8.102	Loss
CMGC_MAPK_ERK1_MAPK1_ST	P49815	TSC2	P28482	MAPK1	S1304	A1297T	1297	Missense	distal	-7	no	15.312	15.298	EPSD	COSMIC;GDSC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P49815	TSC2	P28482	MAPK1	S1304	G1303R	1303	Missense	proximal	-1	no	15.312	15.347	EPSD	COSMIC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P49815	TSC2	P28482	MAPK1	S1388	S1383C	1383	Missense	distal	-5	no	13.389	13.593	EPSD	COSMIC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P49815	TSC2	P28482	MAPK1	S1388	S1383N	1383	Missense	distal	-5	no	13.389	13.341	EPSD	COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P49815	TSC2	P28482	MAPK1	S1388	S1387L	1387	Missense	proximal	-1	no	13.389	13.373	EPSD	COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P49815	TSC2	P28482	MAPK1	S1388	S1383R	1383	Missense	distal	-5	no	13.389	13.363	EPSD	COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P49815	TSC2	P28482	MAPK1	S1388	E1390G	1390	Missense	proximal	2	no	13.389	13.475	EPSD	COSMIC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P49815	TSC2	P28482	MAPK1	S1388	P1389H	1389	Missense	proximal	1	no	13.389	5.566	EPSD	COSMIC	8.102	Loss
CMGC_MAPK_ERK1_MAPK1_ST	P49815	TSC2	P28482	MAPK1	S1388	S1385F	1385	Missense	distal	-3	no	13.389	13.157	EPSD	COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P49815	TSC2	P28482	MAPK1	S1388	E1390D	1390	Missense	proximal	2	no	13.389	13.441	EPSD	COSMIC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P49815	TSC2	P28482	MAPK1	S1411	K1404T	1404	Missense	distal	-7	no	15.321	15.306	EPSD	COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P49815	TSC2	P28482	MAPK1	S1411	R1409Q	1409	Missense	proximal	-2	no	15.321	14.146	EPSD	COSMIC;GDSC;CCLE	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P49815	TSC2	P28482	MAPK1	S1411	G1408V	1408	Missense	distal	-3	no	15.321	15.203	EPSD	COSMIC;GDSC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P49815	TSC2	P28482	MAPK1	S1411	V1407M	1407	Missense	distal	-4	no	15.321	15.210	EPSD	COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P49815	TSC2	P28482	MAPK1	S1411	R1409W	1409	Missense	proximal	-2	no	15.321	14.398	EPSD	COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P49815	TSC2	P28482	MAPK1	S1411	E1413D	1413	Missense	proximal	2	no	15.321	15.373	EPSD	COSMIC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P49815	TSC2	P28482	MAPK1	S1411	P1412T	1412	Missense	proximal	1	no	15.321	6.822	EPSD	COSMIC	8.102	Loss
CMGC_MAPK_ERK1_MAPK1_ST	P49815	TSC2	P28482	MAPK1	S1449	S1454N	1454	Missense	distal	5	no	14.976	14.904	EPSD	COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P49815	TSC2	P28482	MAPK1	S1449	P1446S	1446	Missense	distal	-3	no	14.976	14.800	EPSD	COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P49815	TSC2	P28482	MAPK1	S1449	S1454G	1454	Missense	distal	5	no	14.976	14.957	EPSD	COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P49815	TSC2	P28482	MAPK1	S1449	L1445M	1445	Missense	distal	-4	no	14.976	14.815	EPSD	COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P49815	TSC2	P28482	MAPK1	S1449	R1451I	1451	Missense	proximal	2	no	14.976	14.692	EPSD	COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P49815	TSC2	P28482	MAPK1	S1452	S1454N	1454	Missense	proximal	2	no	18.155	18.107	EPSD	COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P49815	TSC2	P28482	MAPK1	S1452	R1459Q	1459	Missense	distal	7	no	18.155	18.271	EPSD	COSMIC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P49815	TSC2	P28482	MAPK1	S1452	P1446S	1446	Missense	distal	-6	no	18.155	18.129	EPSD	COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P49815	TSC2	P28482	MAPK1	S1452	S1454G	1454	Missense	proximal	2	no	18.155	18.202	EPSD	COSMIC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P49815	TSC2	P28482	MAPK1	S1452	L1445M	1445	Missense	distal	-7	no	18.155	18.146	EPSD	COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P49815	TSC2	P28482	MAPK1	S1452	R1451I	1451	Missense	proximal	-1	no	18.155	18.109	EPSD	COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P49815	TSC2	P28482	MAPK1	S1539	K1544N	1544	Missense	distal	5	no	8.466	8.497	EPSD	COSMIC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P49815	TSC2	P28482	MAPK1	S1539	P1538I	1538	Missense	proximal	-1	no	8.466	8.400	EPSD	COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P49815	TSC2	P28482	MAPK1	S1539	D1535N	1535	Missense	distal	-4	no	8.466	8.438	EPSD	COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P49815	TSC2	P28482	MAPK1	S1539	P1538L	1538	Missense	proximal	-1	no	8.466	8.407	EPSD	COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P49815	TSC2	P28482	MAPK1	S1539	Y1540D	1540	Missense	proximal	1	no	8.466	6.779	EPSD	COSMIC	8.102	Loss
CMGC_MAPK_ERK1_MAPK1_ST	P49815	TSC2	P28482	MAPK1	S1539	D1541A	1541	Missense	proximal	2	no	8.466	8.352	EPSD	COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P49815	TSC2	P28482	MAPK1	S1539	Q1536H	1536	Missense	distal	-3	no	8.466	8.414	EPSD	COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P49815	TSC2	P28482	MAPK1	S1772	S1774T	1774	Missense	proximal	2	no	9.925	9.902	EPSD	COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P49815	TSC2	P28482	MAPK1	S1772	P1770S	1770	Missense	proximal	-2	no	9.925	7.091	EPSD	COSMIC	8.102	Loss
CMGC_MAPK_ERK1_MAPK1_ST	P49815	TSC2	P28482	MAPK1	S1772	P1771L	1771	Missense	proximal	-1	no	9.925	9.865	EPSD	COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P49815	TSC2	P28482	MAPK1	S1772	A1778G	1778	Missense	distal	6	no	9.925	10.144	EPSD	COSMIC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P49815	TSC2	P28482	MAPK1	S1772	A1776G	1776	Missense	distal	4	no	9.925	9.969	EPSD	COSMIC;GDSC;CCLE	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P49815	TSC2	P28482	MAPK1	T1780	P1781L	1781	Missense	proximal	1	no	14.192	5.383	EPSD	COSMIC	8.102	Loss
CMGC_MAPK_ERK1_MAPK1_ST	P49815	TSC2	P28482	MAPK1	T1780	A1782V	1782	Missense	proximal	2	no	14.192	14.268	EPSD	COSMIC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P49815	TSC2	P28482	MAPK1	T1780	S1774T	1774	Missense	distal	-6	no	14.192	14.169	EPSD	COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P49815	TSC2	P28482	MAPK1	T1780	G1787S	1787	Missense	distal	7	no	14.192	14.124	EPSD	COSMIC;GDSC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P49815	TSC2	P28482	MAPK1	T1780	P1786S	1786	Missense	distal	6	no	14.192	14.193	EPSD	COSMIC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P49815	TSC2	P28482	MAPK1	T1780	A1778G	1778	Missense	proximal	-2	no	14.192	14.145	EPSD	COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P49815	TSC2	P28482	MAPK1	T1780	P1786R	1786	Missense	distal	6	no	14.192	14.085	EPSD	COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P49815	TSC2	P28482	MAPK1	T1780	P1784S	1784	Missense	distal	4	no	14.192	14.182	EPSD	COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P49815	TSC2	P28482	MAPK1	T1780	A1776G	1776	Missense	distal	-4	no	14.192	14.136	EPSD	COSMIC;GDSC;CCLE	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P49815	TSC2	P28482	MAPK1	T1780	P1784R	1784	Missense	distal	4	no	14.192	14.159	EPSD	COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P49815	TSC2	P28482	MAPK1	T1785	P1781L	1781	Missense	distal	-4	no	16.624	16.319	EPSD	COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P49815	TSC2	P28482	MAPK1	T1785	A1782V	1782	Missense	distal	-3	no	16.624	16.683	EPSD	COSMIC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P49815	TSC2	P28482	MAPK1	T1785	G1787S	1787	Missense	proximal	2	no	16.624	16.577	EPSD	COSMIC;GDSC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P49815	TSC2	P28482	MAPK1	T1785	P1786S	1786	Missense	proximal	1	no	16.624	7.229	EPSD	COSMIC	8.102	Loss
CMGC_MAPK_ERK1_MAPK1_ST	P49815	TSC2	P28482	MAPK1	T1785	G1791S	1791	Missense	distal	6	no	16.624	16.701	EPSD	COSMIC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P49815	TSC2	P28482	MAPK1	T1785	V1790M	1790	Missense	distal	5	no	16.624	16.562	EPSD	COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P49815	TSC2	P28482	MAPK1	T1785	A1778G	1778	Missense	distal	-7	no	16.624	16.608	EPSD	COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P49815	TSC2	P28482	MAPK1	T1785	P1786R	1786	Missense	proximal	1	no	16.624	6.969	EPSD	COSMIC	8.102	Loss
CMGC_MAPK_ERK1_MAPK1_ST	P49815	TSC2	P28482	MAPK1	T1785	P1784S	1784	Missense	proximal	-1	no	16.624	16.580	EPSD	COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P49815	TSC2	P28482	MAPK1	T1785	P1784R	1784	Missense	proximal	-1	no	16.624	16.604	EPSD	COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P10415	BCL2	P28482	MAPK1	T56	F49C	49	Missense	distal	-7	no	14.539	14.526	EPSD;PhosphoSitePlus	COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P10415	BCL2	P28482	MAPK1	T56	S51Y	51	Missense	distal	-5	no	14.539	14.670	EPSD;PhosphoSitePlus	COSMIC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P10415	BCL2	P28482	MAPK1	T56	P57S	57	Missense	proximal	1	no	14.539	5.144	EPSD;PhosphoSitePlus	COSMIC	8.102	Loss
CMGC_MAPK_ERK1_MAPK1_ST	P10415	BCL2	P28482	MAPK1	T56	F49S	49	Missense	distal	-7	no	14.539	14.559	EPSD;PhosphoSitePlus	COSMIC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P10415	BCL2	P28482	MAPK1	T56	H58L	58	Missense	proximal	2	no	14.539	14.521	EPSD;PhosphoSitePlus	COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P10415	BCL2	P28482	MAPK1	T56	Q52P	52	Missense	distal	-4	no	14.539	14.731	EPSD;PhosphoSitePlus	COSMIC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P10415	BCL2	P28482	MAPK1	T56	S51P	51	Missense	distal	-5	no	14.539	14.465	EPSD;PhosphoSitePlus	COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P10415	BCL2	P28482	MAPK1	T56	S50P	50	Missense	distal	-6	no	14.539	14.565	EPSD;PhosphoSitePlus	COSMIC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P10415	BCL2	P28482	MAPK1	T56	H58R	58	Missense	proximal	2	no	14.539	14.782	EPSD;PhosphoSitePlus	COSMIC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P10415	BCL2	P28482	MAPK1	T56	A60G	60	Missense	distal	4	no	14.539	14.583	EPSD;PhosphoSitePlus	COSMIC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P10415	BCL2	P28482	MAPK1	T56	P57L	57	Missense	proximal	1	no	14.539	5.729	EPSD;PhosphoSitePlus	COSMIC	8.102	Loss
CMGC_MAPK_ERK1_MAPK1_ST	P10415	BCL2	P28482	MAPK1	T56	A60D	60	Missense	distal	4	no	14.539	14.535	EPSD;PhosphoSitePlus	COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P10415	BCL2	P28482	MAPK1	T56	Q52H	52	Missense	distal	-4	no	14.539	14.490	EPSD;PhosphoSitePlus	COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P10415	BCL2	P28482	MAPK1	T56	P57A	57	Missense	proximal	1	no	14.539	6.908	EPSD;PhosphoSitePlus	COSMIC	8.102	Loss
CMGC_MAPK_ERK1_MAPK1_ST	P10415	BCL2	P28482	MAPK1	S70	T74N	74	Missense	distal	4	no	14.461	14.537	EPSD	COSMIC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P10415	BCL2	P28482	MAPK1	S70	T69A	69	Missense	proximal	-1	no	14.461	14.467	EPSD	COSMIC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P10415	BCL2	P28482	MAPK1	S70	A67V	67	Missense	distal	-3	no	14.461	14.521	EPSD	COSMIC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P10415	BCL2	P28482	MAPK1	S70	P65S	65	Missense	distal	-5	no	14.461	14.536	EPSD	COSMIC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P10415	BCL2	P28482	MAPK1	S70	A76T	76	Missense	distal	6	no	14.461	14.548	EPSD	COSMIC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P10415	BCL2	P28482	MAPK1	S70	A77V	77	Missense	distal	7	no	14.461	14.563	EPSD	COSMIC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P10415	BCL2	P28482	MAPK1	S70	P71S	71	Missense	proximal	1	no	14.461	5.067	EPSD	COSMIC	8.102	Loss
CMGC_MAPK_ERK1_MAPK1_ST	P10415	BCL2	P28482	MAPK1	S70	D64G	64	Missense	distal	-6	no	14.461	14.395	EPSD	COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P10415	BCL2	P28482	MAPK1	S70	A76S	76	Missense	distal	6	no	14.461	14.758	EPSD	COSMIC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P10415	BCL2	P28482	MAPK1	S70	T74A	74	Missense	distal	4	no	14.461	14.481	EPSD	COSMIC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P10415	BCL2	P28482	MAPK1	S70	T74I	74	Missense	distal	4	no	14.461	14.408	EPSD	COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P10415	BCL2	P28482	MAPK1	S70	T69P	69	Missense	proximal	-1	no	14.461	14.504	EPSD	COSMIC;CCLE	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P10415	BCL2	P28482	MAPK1	S70	V66I	66	Missense	distal	-4	no	14.461	14.145	EPSD	COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P10415	BCL2	P28482	MAPK1	S70	P65Q	65	Missense	distal	-5	no	14.461	14.586	EPSD	COSMIC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P10415	BCL2	P28482	MAPK1	T74	T74N	74	Missense	central	0	yes	15.881	0.000	PhosphoSitePlus;EPSD	COSMIC	8.102	Loss
CMGC_MAPK_ERK1_MAPK1_ST	P10415	BCL2	P28482	MAPK1	T74	T69A	69	Missense	distal	-5	no	15.881	15.903	PhosphoSitePlus;EPSD	COSMIC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P10415	BCL2	P28482	MAPK1	T74	A67V	67	Missense	distal	-7	no	15.881	15.865	PhosphoSitePlus;EPSD	COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P10415	BCL2	P28482	MAPK1	T74	A76T	76	Missense	proximal	2	no	15.881	15.960	PhosphoSitePlus;EPSD	COSMIC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P10415	BCL2	P28482	MAPK1	T74	A77V	77	Missense	distal	3	no	15.881	15.861	PhosphoSitePlus;EPSD	COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P10415	BCL2	P28482	MAPK1	T74	P71S	71	Missense	distal	-3	no	15.881	15.705	PhosphoSitePlus;EPSD	COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P10415	BCL2	P28482	MAPK1	T74	A76S	76	Missense	proximal	2	no	15.881	15.983	PhosphoSitePlus;EPSD	COSMIC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P10415	BCL2	P28482	MAPK1	T74	T74A	74	Missense	central	0	yes	15.881	0.000	PhosphoSitePlus;EPSD	COSMIC	8.102	Loss
CMGC_MAPK_ERK1_MAPK1_ST	P10415	BCL2	P28482	MAPK1	T74	A80V	80	Missense	distal	6	no	15.881	15.963	PhosphoSitePlus;EPSD	COSMIC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P10415	BCL2	P28482	MAPK1	T74	T74I	74	Missense	central	0	yes	15.881	0.000	PhosphoSitePlus;EPSD	COSMIC	8.102	Loss
CMGC_MAPK_ERK1_MAPK1_ST	P10415	BCL2	P28482	MAPK1	T74	T69P	69	Missense	distal	-5	no	15.881	15.779	PhosphoSitePlus;EPSD	COSMIC;CCLE	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P10415	BCL2	P28482	MAPK1	S87	L86F	86	Missense	proximal	-1	no	14.286	14.256	EPSD;PhosphoSitePlus	COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P10415	BCL2	P28482	MAPK1	S87	A85V	85	Missense	proximal	-2	no	14.286	15.560	EPSD;PhosphoSitePlus	COSMIC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P10415	BCL2	P28482	MAPK1	S87	P91S	91	Missense	distal	4	no	14.286	14.275	EPSD;PhosphoSitePlus	COSMIC;GDSC;CCLE	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P10415	BCL2	P28482	MAPK1	S87	G83E	83	Missense	distal	-4	no	14.286	14.607	EPSD;PhosphoSitePlus	COSMIC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P10415	BCL2	P28482	MAPK1	S87	P91A	91	Missense	distal	4	no	14.286	14.182	EPSD;PhosphoSitePlus	COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P10415	BCL2	P28482	MAPK1	S87	P90T	90	Missense	distal	3	no	14.286	14.347	EPSD;PhosphoSitePlus	COSMIC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P10415	BCL2	P28482	MAPK1	S87	H94Y	94	Missense	distal	7	no	14.286	14.581	EPSD;PhosphoSitePlus	COSMIC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P10415	BCL2	P28482	MAPK1	S87	A85T	85	Missense	proximal	-2	no	14.286	14.733	EPSD;PhosphoSitePlus	COSMIC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P10415	BCL2	P28482	MAPK1	S87	V93L	93	Missense	distal	6	no	14.286	14.094	EPSD;PhosphoSitePlus	COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P10415	BCL2	P28482	MAPK1	S87	P91L	91	Missense	distal	4	no	14.286	14.165	EPSD;PhosphoSitePlus	COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P10415	BCL2	P28482	MAPK1	S87	S87N	87	Missense	central	0	yes	14.286	0.000	EPSD;PhosphoSitePlus	COSMIC	8.102	Loss
CMGC_MAPK_ERK1_MAPK1_ST	P10415	BCL2	P28482	MAPK1	S87	A80V	80	Missense	distal	-7	no	14.286	14.269	EPSD;PhosphoSitePlus	COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q9NQ66	PLCB1	P28482	MAPK1	T39	P40S	40	Missense	proximal	1	no	15.441	6.046	EPSD	COSMIC	8.102	Loss
CMGC_MAPK_ERK1_MAPK1_ST	Q9NQ66	PLCB1	P28482	MAPK1	S387	I386T	386	Missense	proximal	-1	no	8.431	8.455	EPSD	COSMIC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q9NQ66	PLCB1	P28482	MAPK1	S387	K389M	389	Missense	proximal	2	no	8.431	8.308	EPSD	COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q9NQ66	PLCB1	P28482	MAPK1	S410	N413K	413	Missense	distal	3	no	9.459	9.465	EPSD	COSMIC;GDSC;CCLE	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q9NQ66	PLCB1	P28482	MAPK1	S410	D416V	416	Missense	distal	6	no	9.459	9.289	EPSD	COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q9NQ66	PLCB1	P28482	MAPK1	S410	S403L	403	Missense	distal	-7	no	9.459	9.451	EPSD	COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q9NQ66	PLCB1	P28482	MAPK1	S410	L409F	409	Missense	proximal	-1	no	9.459	9.429	EPSD	COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q9NQ66	PLCB1	P28482	MAPK1	S410	P406S	406	Missense	distal	-4	no	9.459	9.375	EPSD	COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q9NQ66	PLCB1	P28482	MAPK1	S410	L408F	408	Missense	proximal	-2	no	9.459	8.735	EPSD	COSMIC;GDSC;CCLE	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q9NQ66	PLCB1	P28482	MAPK1	S410	D416N	416	Missense	distal	6	no	9.459	9.408	EPSD	COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q9NQ66	PLCB1	P28482	MAPK1	S417	N413K	413	Missense	distal	-4	no	16.300	16.331	EPSD	COSMIC;GDSC;CCLE	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q9NQ66	PLCB1	P28482	MAPK1	S417	D416V	416	Missense	proximal	-1	no	16.300	16.329	EPSD	COSMIC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q9NQ66	PLCB1	P28482	MAPK1	S417	P418S	418	Missense	proximal	1	no	16.300	6.905	EPSD	COSMIC	8.102	Loss
CMGC_MAPK_ERK1_MAPK1_ST	Q9NQ66	PLCB1	P28482	MAPK1	S417	K423E	423	Missense	distal	6	no	16.300	16.276	EPSD	COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q9NQ66	PLCB1	P28482	MAPK1	S417	D416N	416	Missense	proximal	-1	no	16.300	16.361	EPSD	COSMIC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q9NQ66	PLCB1	P28482	MAPK1	S454	E447K	447	Missense	distal	-7	no	11.664	11.657	EPSD	COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q9NQ66	PLCB1	P28482	MAPK1	S454	M456I	456	Missense	proximal	2	no	11.664	11.684	EPSD	COSMIC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q9NQ66	PLCB1	P28482	MAPK1	S454	Y460C	460	Missense	distal	6	no	11.664	11.415	EPSD	COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q9NQ66	PLCB1	P28482	MAPK1	S454	K461I	461	Missense	distal	7	no	11.664	12.263	EPSD	COSMIC;GDSC;CCLE	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q9NQ66	PLCB1	P28482	MAPK1	S501	G503E	503	Missense	proximal	2	no	17.571	17.485	EPSD	COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q9NQ66	PLCB1	P28482	MAPK1	S582	G575R	575	Missense	distal	-7	no	13.843	13.856	EPSD	COSMIC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q9NQ66	PLCB1	P28482	MAPK1	S582	G575E	575	Missense	distal	-7	no	13.843	13.866	EPSD	COSMIC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q9NQ66	PLCB1	P28482	MAPK1	S582	Y589S	589	Missense	distal	7	no	13.843	13.325	EPSD	COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q9NQ66	PLCB1	P28482	MAPK1	S582	P583A	583	Missense	proximal	1	no	13.843	6.213	EPSD	COSMIC	8.102	Loss
CMGC_MAPK_ERK1_MAPK1_ST	Q9NQ66	PLCB1	P28482	MAPK1	S582	E585K	585	Missense	distal	3	no	13.843	13.850	EPSD	COSMIC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q9NQ66	PLCB1	P28482	MAPK1	T871	T869I	869	Missense	proximal	-2	no	13.510	14.315	EPSD	COSMIC;CCLE	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q9NQ66	PLCB1	P28482	MAPK1	T871	H866R	866	Missense	distal	-5	no	13.510	13.433	EPSD	COSMIC;CCLE	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q9NQ66	PLCB1	P28482	MAPK1	T871	Q877K	877	Missense	distal	6	no	13.510	13.855	EPSD	COSMIC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q9NQ66	PLCB1	P28482	MAPK1	S982	D984H	984	Missense	proximal	2	no	16.923	16.809	PhosphoSitePlus	COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q9NQ66	PLCB1	P28482	MAPK1	S982	E979K	979	Missense	distal	-3	no	16.923	16.845	PhosphoSitePlus	COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q9NQ66	PLCB1	P28482	MAPK1	T1197	E1202K	1202	Missense	distal	5	no	16.585	16.526	EPSD	COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q9NQ66	PLCB1	P28482	MAPK1	T1197	P1198L	1198	Missense	proximal	1	no	16.585	7.775	EPSD	COSMIC	8.102	Loss
CMGC_MAPK_ERK1_MAPK1_ST	Q9NQ66	PLCB1	P28482	MAPK1	T1197	P1190N	1190	Missense	distal	-7	no	16.585	16.583	EPSD	COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q9NQ66	PLCB1	P28482	MAPK1	T1197	S1199Y	1199	Missense	proximal	2	no	16.585	16.417	EPSD	COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q9NQ66	PLCB1	P28482	MAPK1	S1199	E1202K	1202	Missense	distal	3	no	8.231	8.237	EPSD	COSMIC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q9NQ66	PLCB1	P28482	MAPK1	S1199	P1198L	1198	Missense	proximal	-1	no	8.231	8.171	EPSD	COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q9NQ66	PLCB1	P28482	MAPK1	S1199	S1199Y	1199	Missense	central	0	yes	8.231	0.000	EPSD	COSMIC	8.102	Loss
CMGC_MAPK_ERK1_MAPK1_ST	Q9NQ66	PLCB1	P28482	MAPK1	S1200	P1198L	1198	Missense	proximal	-2	no	10.684	8.767	EPSD	COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q9NQ66	PLCB1	P28482	MAPK1	S1200	S1199Y	1199	Missense	proximal	-1	no	10.684	10.652	EPSD	COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q15554	TERF2	P28482	MAPK1	T169	E165K	165	Missense	distal	-4	no	11.467	11.485	EPSD	COSMIC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q15554	TERF2	P28482	MAPK1	T169	E165D	165	Missense	distal	-4	no	11.467	11.481	EPSD	COSMIC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q15554	TERF2	P28482	MAPK1	T169	L168R	168	Missense	proximal	-1	no	11.467	11.507	EPSD	COSMIC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q15554	TERF2	P28482	MAPK1	S365	L368P	368	Missense	distal	3	no	16.568	16.479	PhosphoSitePlus	COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P17655	CAPN2	P28482	MAPK1	S50	P52Q	52	Missense	proximal	2	no	8.446	8.268	PhosphoSitePlus	COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P17655	CAPN2	P28482	MAPK1	S277	E271D	271	Missense	distal	-6	no	8.508	8.520	EPSD	COSMIC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P17655	CAPN2	P28482	MAPK1	S277	V272A	272	Missense	distal	-5	no	8.508	8.537	EPSD	COSMIC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P17655	CAPN2	P28482	MAPK1	T344	R337C	337	Missense	distal	-7	no	12.479	12.447	EPSD	COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P17655	CAPN2	P28482	MAPK1	T464	R461H	461	Missense	distal	-3	no	8.285	7.955	EPSD	COSMIC	8.102	Loss
CMGC_MAPK_ERK1_MAPK1_ST	P17655	CAPN2	P28482	MAPK1	T464	R469W	469	Missense	distal	5	no	8.285	7.756	EPSD	COSMIC;GDSC;CCLE	8.102	Loss
CMGC_MAPK_ERK1_MAPK1_ST	P17655	CAPN2	P28482	MAPK1	T464	R461S	461	Missense	distal	-3	no	8.285	8.128	EPSD	COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P30041	PRDX6	P28482	MAPK1	T44	T48I	48	Missense	distal	4	no	13.824	13.770	EPSD	COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P30041	PRDX6	P28482	MAPK1	T177	A171T	171	Missense	distal	-6	no	13.903	13.893	PhosphoSitePlus	COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P30041	PRDX6	P28482	MAPK1	T177	G184R	184	Missense	distal	7	no	13.903	13.838	PhosphoSitePlus	COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P30041	PRDX6	P28482	MAPK1	T177	V175G	175	Missense	proximal	-2	no	13.903	12.582	PhosphoSitePlus	COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P30041	PRDX6	P28482	MAPK1	T177	D180E	180	Missense	distal	3	no	13.903	13.808	PhosphoSitePlus	COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P30041	PRDX6	P28482	MAPK1	T177	A176T	176	Missense	proximal	-1	no	13.903	13.898	PhosphoSitePlus	COSMIC;GDSC;CCLE	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q9BY84	DUSP16	P28482	MAPK1	S446	F445L	445	Missense	proximal	-1	no	13.637	13.667	PhosphoSitePlus	COSMIC;GDSC;CCLE	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q9BY84	DUSP16	P28482	MAPK1	S459	E464G	464	Missense	distal	5	no	14.430	14.455	EPSD	COSMIC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q9BY84	DUSP16	P28482	MAPK1	S501	A495T	495	Missense	distal	-6	no	14.135	14.125	EPSD	COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q9BY84	DUSP16	P28482	MAPK1	S501	L500S	500	Missense	proximal	-1	no	14.135	14.152	EPSD	COSMIC;CCLE	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	O75030	MITF	P28482	MAPK1	S175	V168F	168	Missense	distal	-7	no	8.206	8.201	EPSD	COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	O75030	MITF	P28482	MAPK1	S175	A177V	177	Missense	proximal	2	no	8.206	8.283	EPSD	COSMIC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	O75030	MITF	P28482	MAPK1	S175	N179I	179	Missense	distal	4	no	8.206	8.078	EPSD	COSMIC	8.102	Loss
CMGC_MAPK_ERK1_MAPK1_ST	O75030	MITF	P28482	MAPK1	S175	P170L	170	Missense	distal	-5	no	8.206	8.355	EPSD	COSMIC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	O75030	MITF	P28482	MAPK1	S175	P170S	170	Missense	distal	-5	no	8.206	8.281	EPSD	COSMIC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	O75030	MITF	P28482	MAPK1	S180	A177V	177	Missense	distal	-3	no	17.567	17.626	EPSD	COSMIC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	O75030	MITF	P28482	MAPK1	S180	N179I	179	Missense	proximal	-1	no	17.567	17.495	EPSD	COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	O75030	MITF	P28482	MAPK1	S414	R420Q	420	Missense	distal	6	no	15.800	15.619	EPSD	COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	O75030	MITF	P28482	MAPK1	S414	C413F	413	Missense	proximal	-1	no	15.800	15.832	EPSD	COSMIC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	O75030	MITF	P28482	MAPK1	S491	V493I	493	Missense	proximal	2	no	13.748	13.631	EPSD	COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	O75030	MITF	P28482	MAPK1	S491	D487N	487	Missense	distal	-4	no	13.748	13.720	EPSD	COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	O75030	MITF	P28482	MAPK1	S491	T489N	489	Missense	proximal	-2	no	13.748	13.628	EPSD	COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	O75030	MITF	P28482	MAPK1	S504	S504F	504	Missense	central	0	yes	14.819	0.000	EPSD	COSMIC	8.102	Loss
CMGC_MAPK_ERK1_MAPK1_ST	O75030	MITF	P28482	MAPK1	S504	A507T	507	Missense	distal	3	no	14.819	14.803	EPSD	COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	O75030	MITF	P28482	MAPK1	S504	S511I	511	Missense	distal	7	no	14.819	15.367	EPSD	COSMIC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	O75030	MITF	P28482	MAPK1	S511	S512I	512	Missense	proximal	1	no	9.061	8.638	EPSD	COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	O75030	MITF	P28482	MAPK1	S511	S504F	504	Missense	distal	-7	no	9.061	9.041	EPSD	COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	O75030	MITF	P28482	MAPK1	S511	A507T	507	Missense	distal	-4	no	9.061	9.041	EPSD	COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	O75030	MITF	P28482	MAPK1	S511	R513W	513	Missense	proximal	2	no	9.061	8.693	EPSD	COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	O75030	MITF	P28482	MAPK1	S511	S518I	518	Missense	distal	7	no	9.061	9.609	EPSD	COSMIC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	O75030	MITF	P28482	MAPK1	S511	S511I	511	Missense	central	0	yes	9.061	0.000	EPSD	COSMIC	8.102	Loss
CMGC_MAPK_ERK1_MAPK1_ST	O75030	MITF	P28482	MAPK1	S512	R513W	513	Missense	proximal	1	no	7.732	10.010	EPSD	COSMIC	8.102	Gain
CMGC_MAPK_ERK1_MAPK1_ST	O75030	MITF	P28482	MAPK1	S515	S512I	512	Missense	distal	-3	no	8.809	8.544	EPSD	COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	O75030	MITF	P28482	MAPK1	S515	R513W	513	Missense	proximal	-2	no	8.809	7.886	EPSD	COSMIC	8.102	Loss
CMGC_MAPK_ERK1_MAPK1_ST	O75030	MITF	P28482	MAPK1	S515	T522M	522	Missense	distal	7	no	8.809	9.017	EPSD	COSMIC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	O75030	MITF	P28482	MAPK1	S515	S518I	518	Missense	distal	3	no	8.809	8.867	EPSD	COSMIC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	O75030	MITF	P28482	MAPK1	S515	S511I	511	Missense	distal	-4	no	8.809	8.222	EPSD	COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P03372	ESR1	P28482	MAPK1	S104	F97L	97	Missense	distal	-7	no	13.696	13.708	EPSD;PhosphoSitePlus	COSMIC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P03372	ESR1	P28482	MAPK1	S104	M109T	109	Missense	distal	5	no	13.696	13.827	EPSD;PhosphoSitePlus	COSMIC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P03372	ESR1	P28482	MAPK1	S106	P113L	113	Missense	distal	7	no	13.462	13.761	EPSD;PhosphoSitePlus	COSMIC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P03372	ESR1	P28482	MAPK1	S106	P113Q	113	Missense	distal	7	no	13.462	13.592	EPSD;PhosphoSitePlus	COSMIC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P03372	ESR1	P28482	MAPK1	S106	H112L	112	Missense	distal	6	no	13.462	13.361	EPSD;PhosphoSitePlus	COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P03372	ESR1	P28482	MAPK1	S106	M109T	109	Missense	distal	3	no	13.462	13.439	EPSD;PhosphoSitePlus	COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P03372	ESR1	P28482	MAPK1	S118	P113L	113	Missense	distal	-5	no	12.971	13.120	PhosphoSitePlus;EPSD	COSMIC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P03372	ESR1	P28482	MAPK1	S118	P113Q	113	Missense	distal	-5	no	12.971	13.096	PhosphoSitePlus;EPSD	COSMIC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P03372	ESR1	P28482	MAPK1	S118	L117Q	117	Missense	proximal	-1	no	12.971	12.990	PhosphoSitePlus;EPSD	COSMIC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P03372	ESR1	P28482	MAPK1	S118	H112L	112	Missense	distal	-6	no	12.971	12.954	PhosphoSitePlus;EPSD	COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P03372	ESR1	P28482	MAPK1	S118	S118P	118	Missense	central	0	yes	12.971	0.000	PhosphoSitePlus;EPSD	COSMIC	8.102	Loss
CMGC_MAPK_ERK1_MAPK1_ST	P03372	ESR1	P28482	MAPK1	S167	G172R	172	Missense	distal	5	no	8.379	8.430	EPSD	COSMIC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P03372	ESR1	P28482	MAPK1	S167	M174I	174	Missense	distal	7	no	8.379	8.567	EPSD	COSMIC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P03372	ESR1	P28482	MAPK1	S167	D170Y	170	Missense	distal	3	no	8.379	8.420	EPSD	COSMIC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P03372	ESR1	P28482	MAPK1	S167	G160D	160	Missense	distal	-7	no	8.379	8.394	EPSD	COSMIC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P03372	ESR1	P28482	MAPK1	S294	K299R	299	Missense	distal	5	no	14.197	14.332	EPSD	COSMIC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P03372	ESR1	P28482	MAPK1	S294	P295L	295	Missense	proximal	1	no	14.197	5.387	EPSD	COSMIC	8.102	Loss
CMGC_MAPK_ERK1_MAPK1_ST	P03372	ESR1	P28482	MAPK1	S294	R300C	300	Missense	distal	6	no	14.197	13.437	EPSD	COSMIC;CCLE	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P03372	ESR1	P28482	MAPK1	S294	L296P	296	Missense	proximal	2	no	14.197	14.345	EPSD	COSMIC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P03372	ESR1	P28482	MAPK1	S294	N290K	290	Missense	distal	-4	no	14.197	14.229	EPSD	COSMIC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P03372	ESR1	P28482	MAPK1	S294	S294R	294	Missense	central	0	yes	14.197	0.000	EPSD	COSMIC	8.102	Loss
CMGC_MAPK_ERK1_MAPK1_ST	P03372	ESR1	P28482	MAPK1	S294	A288T	288	Missense	distal	-6	no	14.197	14.187	EPSD	COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P03372	ESR1	P28482	MAPK1	S294	R287H	287	Missense	distal	-7	no	14.197	14.186	EPSD	COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P03372	ESR1	P28482	MAPK1	S294	R287C	287	Missense	distal	-7	no	14.197	14.165	EPSD	COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P03372	ESR1	P28482	MAPK1	S576	S578Y	578	Missense	proximal	2	no	8.436	8.269	EPSD	COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P09874	PARP1	P28482	MAPK1	S41	V39M	39	Missense	proximal	-2	no	14.960	12.818	EPSD	COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P09874	PARP1	P28482	MAPK1	T327	V334E	334	Missense	distal	7	no	9.732	9.390	EPSD	COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P09874	PARP1	P28482	MAPK1	T335	R340L	340	Missense	distal	5	no	14.092	13.829	EPSD	COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P09874	PARP1	P28482	MAPK1	T335	V334E	334	Missense	proximal	-1	no	14.092	14.103	EPSD	COSMIC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P09874	PARP1	P28482	MAPK1	T361	S364F	364	Missense	distal	3	no	8.042	8.105	EPSD	COSMIC	8.102	Gain
CMGC_MAPK_ERK1_MAPK1_ST	P09874	PARP1	P28482	MAPK1	T368	P370S	370	Missense	proximal	2	no	13.208	13.180	EPSD	COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P09874	PARP1	P28482	MAPK1	T368	T361N	361	Missense	distal	-7	no	13.208	13.223	EPSD	COSMIC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P09874	PARP1	P28482	MAPK1	T368	S372F	372	Missense	distal	4	no	13.208	13.030	EPSD	COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P09874	PARP1	P28482	MAPK1	T368	S364F	364	Missense	distal	-4	no	13.208	12.947	EPSD	COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P09874	PARP1	P28482	MAPK1	S372	P377S	377	Missense	distal	5	no	8.983	9.001	PhosphoSitePlus;EPSD	COSMIC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P09874	PARP1	P28482	MAPK1	S372	P370S	370	Missense	proximal	-2	no	8.983	6.149	PhosphoSitePlus;EPSD	COSMIC	8.102	Loss
CMGC_MAPK_ERK1_MAPK1_ST	P09874	PARP1	P28482	MAPK1	S372	S372F	372	Missense	central	0	yes	8.983	0.000	PhosphoSitePlus;EPSD	COSMIC	8.102	Loss
CMGC_MAPK_ERK1_MAPK1_ST	P09874	PARP1	P28482	MAPK1	T373	P377S	377	Missense	distal	4	no	10.488	10.478	EPSD;PhosphoSitePlus	COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P09874	PARP1	P28482	MAPK1	T373	V380M	380	Missense	distal	7	no	10.488	10.565	EPSD;PhosphoSitePlus	COSMIC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P09874	PARP1	P28482	MAPK1	T373	P370S	370	Missense	distal	-3	no	10.488	10.312	EPSD;PhosphoSitePlus	COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P09874	PARP1	P28482	MAPK1	T373	S372F	372	Missense	proximal	-1	no	10.488	10.442	EPSD;PhosphoSitePlus	COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P09874	PARP1	P28482	MAPK1	S479	S479F	479	Missense	central	0	yes	14.080	0.000	EPSD	COSMIC	8.102	Loss
CMGC_MAPK_ERK1_MAPK1_ST	P09874	PARP1	P28482	MAPK1	S479	H476N	476	Missense	distal	-3	no	14.080	14.268	EPSD	COSMIC;CCLE	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P09874	PARP1	P28482	MAPK1	S479	W481C	481	Missense	proximal	2	no	14.080	14.075	EPSD	COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P09874	PARP1	P28482	MAPK1	S479	L474S	474	Missense	distal	-5	no	14.080	14.005	EPSD	COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P09874	PARP1	P28482	MAPK1	S554	G550R	550	Missense	distal	-4	no	8.342	8.602	EPSD	COSMIC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P09874	PARP1	P28482	MAPK1	S554	G558V	558	Missense	distal	4	no	8.342	8.292	EPSD	COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P09874	PARP1	P28482	MAPK1	S554	K551R	551	Missense	distal	-3	no	8.342	8.580	EPSD	COSMIC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q969V6	MRTFA	P28482	MAPK1	S6	L4F	4	Missense	proximal	-2	no	17.161	16.438	EPSD	COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q969V6	MRTFA	P28482	MAPK1	S6	P2S	2	Missense	distal	-4	no	17.161	17.078	EPSD	COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q969V6	MRTFA	P28482	MAPK1	S6	E12D	12	Missense	distal	6	no	17.161	17.082	EPSD	COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q969V6	MRTFA	P28482	MAPK1	S6	P2L	2	Missense	distal	-4	no	17.161	16.857	EPSD	COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q969V6	MRTFA	P28482	MAPK1	S6	K5E	5	Missense	proximal	-1	no	17.161	17.133	EPSD	COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q969V6	MRTFA	P28482	MAPK1	S6	P2R	2	Missense	distal	-4	no	17.161	17.072	EPSD	COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q969V6	MRTFA	P28482	MAPK1	S16	R21W	21	Missense	distal	5	no	9.345	8.816	EPSD	COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q969V6	MRTFA	P28482	MAPK1	S16	R19W	19	Missense	distal	3	no	9.345	9.494	EPSD	COSMIC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q969V6	MRTFA	P28482	MAPK1	S16	R21G	21	Missense	distal	5	no	9.345	9.294	EPSD	COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q969V6	MRTFA	P28482	MAPK1	S16	E12D	12	Missense	distal	-4	no	9.345	9.359	EPSD	COSMIC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q969V6	MRTFA	P28482	MAPK1	S16	E23D	23	Missense	distal	7	no	9.345	9.400	EPSD	COSMIC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q969V6	MRTFA	P28482	MAPK1	S16	S16R	16	Missense	central	0	yes	9.345	0.000	EPSD	COSMIC	8.102	Loss
CMGC_MAPK_ERK1_MAPK1_ST	Q969V6	MRTFA	P28482	MAPK1	S124	E126G	126	Missense	proximal	2	no	13.215	13.301	EPSD	COSMIC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q969V6	MRTFA	P28482	MAPK1	S124	P125L	125	Missense	proximal	1	no	13.215	4.405	EPSD	COSMIC	8.102	Loss
CMGC_MAPK_ERK1_MAPK1_ST	Q969V6	MRTFA	P28482	MAPK1	S124	D121N	121	Missense	distal	-3	no	13.215	13.183	EPSD	COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q969V6	MRTFA	P28482	MAPK1	S124	E117K	117	Missense	distal	-7	no	13.215	13.208	EPSD	COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q969V6	MRTFA	P28482	MAPK1	S130	E126G	126	Missense	distal	-4	no	9.963	9.642	EPSD	COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q969V6	MRTFA	P28482	MAPK1	S130	E126K	126	Missense	distal	-4	no	9.963	9.981	EPSD	COSMIC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q969V6	MRTFA	P28482	MAPK1	S130	P125L	125	Missense	distal	-5	no	9.963	10.112	EPSD	COSMIC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q969V6	MRTFA	P28482	MAPK1	S139	P138L	138	Missense	proximal	-1	no	14.820	14.760	EPSD	COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q969V6	MRTFA	P28482	MAPK1	S139	R144G	144	Missense	distal	5	no	14.820	14.769	EPSD	COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q969V6	MRTFA	P28482	MAPK1	S156	P157H	157	Missense	proximal	1	no	15.482	7.658	EPSD	COSMIC	8.102	Loss
CMGC_MAPK_ERK1_MAPK1_ST	Q969V6	MRTFA	P28482	MAPK1	S156	S154C	154	Missense	proximal	-2	no	15.482	14.549	EPSD	COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q969V6	MRTFA	P28482	MAPK1	S156	P157S	157	Missense	proximal	1	no	15.482	6.087	EPSD	COSMIC	8.102	Loss
CMGC_MAPK_ERK1_MAPK1_ST	Q969V6	MRTFA	P28482	MAPK1	S156	Q163P	163	Missense	distal	7	no	15.482	15.352	EPSD	COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q969V6	MRTFA	P28482	MAPK1	S162	Q163P	163	Missense	proximal	1	no	5.447	13.941	EPSD	COSMIC	8.102	Gain
CMGC_MAPK_ERK1_MAPK1_ST	Q969V6	MRTFA	P28482	MAPK1	T204	P205S	205	Missense	proximal	1	no	13.023	3.628	EPSD	COSMIC	8.102	Loss
CMGC_MAPK_ERK1_MAPK1_ST	Q969V6	MRTFA	P28482	MAPK1	T204	P205H	205	Missense	proximal	1	no	13.023	5.199	EPSD	COSMIC	8.102	Loss
CMGC_MAPK_ERK1_MAPK1_ST	Q969V6	MRTFA	P28482	MAPK1	T204	K202T	202	Missense	proximal	-2	no	13.023	12.743	EPSD	COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q969V6	MRTFA	P28482	MAPK1	T204	K202E	202	Missense	proximal	-2	no	13.023	13.062	EPSD	COSMIC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q969V6	MRTFA	P28482	MAPK1	T204	P205L	205	Missense	proximal	1	no	13.023	4.213	EPSD	COSMIC	8.102	Loss
CMGC_MAPK_ERK1_MAPK1_ST	Q969V6	MRTFA	P28482	MAPK1	T305	P307S	307	Missense	proximal	2	no	13.815	13.787	EPSD	COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q969V6	MRTFA	P28482	MAPK1	T305	R309C	309	Missense	distal	4	no	13.815	13.555	EPSD	COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q969V6	MRTFA	P28482	MAPK1	T305	E298K	298	Missense	distal	-7	no	13.815	13.808	EPSD	COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q969V6	MRTFA	P28482	MAPK1	T305	S312P	312	Missense	distal	7	no	13.815	13.804	EPSD	COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q969V6	MRTFA	P28482	MAPK1	T305	S302R	302	Missense	distal	-3	no	13.815	13.971	EPSD	COSMIC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q969V6	MRTFA	P28482	MAPK1	T305	S303R	303	Missense	proximal	-2	no	13.815	14.830	EPSD	COSMIC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q969V6	MRTFA	P28482	MAPK1	S385	P391L	391	Missense	distal	6	no	13.430	13.023	EPSD	COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q969V6	MRTFA	P28482	MAPK1	T450	P457S	457	Missense	distal	7	no	12.610	12.621	EPSD	COSMIC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q969V6	MRTFA	P28482	MAPK1	T450	G448S	448	Missense	proximal	-2	no	12.610	12.970	EPSD	COSMIC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q969V6	MRTFA	P28482	MAPK1	T450	P451S	451	Missense	proximal	1	no	12.610	3.215	EPSD	COSMIC	8.102	Loss
CMGC_MAPK_ERK1_MAPK1_ST	Q969V6	MRTFA	P28482	MAPK1	T450	T447M	447	Missense	distal	-3	no	12.610	12.382	EPSD	COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q969V6	MRTFA	P28482	MAPK1	T450	P452S	452	Missense	proximal	2	no	12.610	12.582	EPSD	COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q969V6	MRTFA	P28482	MAPK1	S454	P457S	457	Missense	distal	3	no	16.409	16.479	PhosphoSitePlus	COSMIC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q969V6	MRTFA	P28482	MAPK1	S454	R460H	460	Missense	distal	6	no	16.409	16.211	PhosphoSitePlus	COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q969V6	MRTFA	P28482	MAPK1	S454	G448S	448	Missense	distal	-6	no	16.409	16.426	PhosphoSitePlus	COSMIC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q969V6	MRTFA	P28482	MAPK1	S454	P451S	451	Missense	distal	-3	no	16.409	16.233	PhosphoSitePlus	COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q969V6	MRTFA	P28482	MAPK1	S454	R460L	460	Missense	distal	6	no	16.409	16.110	PhosphoSitePlus	COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q969V6	MRTFA	P28482	MAPK1	S454	T447M	447	Missense	distal	-7	no	16.409	16.405	PhosphoSitePlus	COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q969V6	MRTFA	P28482	MAPK1	S454	P452S	452	Missense	proximal	-2	no	16.409	13.575	PhosphoSitePlus	COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q969V6	MRTFA	P28482	MAPK1	T456	P457S	457	Missense	proximal	1	no	13.745	4.350	EPSD	COSMIC	8.102	Loss
CMGC_MAPK_ERK1_MAPK1_ST	Q969V6	MRTFA	P28482	MAPK1	T456	R460H	460	Missense	distal	4	no	13.745	13.603	EPSD	COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q969V6	MRTFA	P28482	MAPK1	T456	P451S	451	Missense	distal	-5	no	13.745	13.819	EPSD	COSMIC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q969V6	MRTFA	P28482	MAPK1	T456	R460L	460	Missense	distal	4	no	13.745	13.658	EPSD	COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q969V6	MRTFA	P28482	MAPK1	T456	P452S	452	Missense	distal	-4	no	13.745	13.661	EPSD	COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q969V6	MRTFA	P28482	MAPK1	T471	G477C	477	Missense	distal	6	no	13.144	12.354	EPSD	COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q969V6	MRTFA	P28482	MAPK1	T471	G473V	473	Missense	proximal	2	no	13.144	13.072	EPSD	COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q969V6	MRTFA	P28482	MAPK1	T471	P472H	472	Missense	proximal	1	no	13.144	5.320	EPSD	COSMIC	8.102	Loss
CMGC_MAPK_ERK1_MAPK1_ST	Q969V6	MRTFA	P28482	MAPK1	T471	G473R	473	Missense	proximal	2	no	13.144	13.239	EPSD	COSMIC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q969V6	MRTFA	P28482	MAPK1	T471	E468D	468	Missense	distal	-3	no	13.144	13.195	EPSD	COSMIC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q969V6	MRTFA	P28482	MAPK1	T471	D474G	474	Missense	distal	3	no	13.144	13.141	EPSD	COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q969V6	MRTFA	P28482	MAPK1	T471	E468K	468	Missense	distal	-3	no	13.144	13.066	EPSD	COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q969V6	MRTFA	P28482	MAPK1	T471	D474Y	474	Missense	distal	3	no	13.144	13.185	EPSD	COSMIC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q969V6	MRTFA	P28482	MAPK1	T471	P472T	472	Missense	proximal	1	no	13.144	4.645	EPSD	COSMIC	8.102	Loss
CMGC_MAPK_ERK1_MAPK1_ST	Q969V6	MRTFA	P28482	MAPK1	S482	G477C	477	Missense	distal	-5	no	14.894	15.103	EPSD	COSMIC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q969V6	MRTFA	P28482	MAPK1	S482	M479T	479	Missense	distal	-3	no	14.894	15.122	EPSD	COSMIC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q969V6	MRTFA	P28482	MAPK1	S482	T485M	485	Missense	distal	3	no	14.894	14.917	EPSD	COSMIC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q969V6	MRTFA	P28482	MAPK1	S482	L489P	489	Missense	distal	7	no	14.894	14.594	EPSD	COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q969V6	MRTFA	P28482	MAPK1	S482	T488A	488	Missense	distal	6	no	14.894	14.808	EPSD	COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q969V6	MRTFA	P28482	MAPK1	S482	T485A	485	Missense	distal	3	no	14.894	14.910	EPSD	COSMIC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q969V6	MRTFA	P28482	MAPK1	S482	P483H	483	Missense	proximal	1	no	14.894	7.070	EPSD	COSMIC	8.102	Loss
CMGC_MAPK_ERK1_MAPK1_ST	Q969V6	MRTFA	P28482	MAPK1	S482	T488M	488	Missense	distal	6	no	14.894	14.671	EPSD	COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q969V6	MRTFA	P28482	MAPK1	S511	A516G	516	Missense	distal	5	no	12.276	12.417	EPSD	COSMIC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q969V6	MRTFA	P28482	MAPK1	S511	A516T	516	Missense	distal	5	no	12.276	12.362	EPSD	COSMIC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q969V6	MRTFA	P28482	MAPK1	S511	P512H	512	Missense	proximal	1	no	12.276	4.453	EPSD	COSMIC	8.102	Loss
CMGC_MAPK_ERK1_MAPK1_ST	Q969V6	MRTFA	P28482	MAPK1	S511	G513E	513	Missense	proximal	2	no	12.276	12.191	EPSD	COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q969V6	MRTFA	P28482	MAPK1	S511	P512S	512	Missense	proximal	1	no	12.276	2.881	EPSD	COSMIC	8.102	Loss
CMGC_MAPK_ERK1_MAPK1_ST	Q969V6	MRTFA	P28482	MAPK1	S511	L518V	518	Missense	distal	7	no	12.276	12.271	EPSD	COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q969V6	MRTFA	P28482	MAPK1	S511	C509Y	509	Missense	proximal	-2	no	12.276	13.925	EPSD	COSMIC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q969V6	MRTFA	P28482	MAPK1	S511	R515L	515	Missense	distal	4	no	12.276	12.189	EPSD	COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q969V6	MRTFA	P28482	MAPK1	S511	R504L	504	Missense	distal	-7	no	12.276	12.269	EPSD	COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q969V6	MRTFA	P28482	MAPK1	S511	A516V	516	Missense	distal	5	no	12.276	12.293	EPSD	COSMIC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q969V6	MRTFA	P28482	MAPK1	S511	R515Q	515	Missense	distal	4	no	12.276	12.202	EPSD	COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q969V6	MRTFA	P28482	MAPK1	S511	R515W	515	Missense	distal	4	no	12.276	11.993	EPSD	COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q969V6	MRTFA	P28482	MAPK1	S511	G514E	514	Missense	distal	3	no	12.276	12.184	EPSD	COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q969V6	MRTFA	P28482	MAPK1	T573	L571P	571	Missense	proximal	-2	no	13.568	15.485	EPSD	COSMIC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q969V6	MRTFA	P28482	MAPK1	T573	A569P	569	Missense	distal	-4	no	13.568	13.861	EPSD	COSMIC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q969V6	MRTFA	P28482	MAPK1	T573	K576R	576	Missense	distal	3	no	13.568	13.616	EPSD	COSMIC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q969V6	MRTFA	P28482	MAPK1	T573	A567P	567	Missense	distal	-6	no	13.568	13.607	EPSD	COSMIC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q969V6	MRTFA	P28482	MAPK1	T573	P566L	566	Missense	distal	-7	no	13.568	13.556	EPSD	COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q969V6	MRTFA	P28482	MAPK1	T573	T573M	573	Missense	central	0	yes	13.568	0.000	EPSD	COSMIC	8.102	Loss
CMGC_MAPK_ERK1_MAPK1_ST	Q969V6	MRTFA	P28482	MAPK1	S695	S695L	695	Missense	central	0	yes	17.547	0.000	EPSD	COSMIC	8.102	Loss
CMGC_MAPK_ERK1_MAPK1_ST	Q969V6	MRTFA	P28482	MAPK1	S695	A699V	699	Missense	distal	4	no	17.547	17.541	EPSD	COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q969V6	MRTFA	P28482	MAPK1	S695	P698R	698	Missense	distal	3	no	17.547	17.593	EPSD	COSMIC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q969V6	MRTFA	P28482	MAPK1	S695	S701F	701	Missense	distal	6	no	17.547	17.106	EPSD	COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q969V6	MRTFA	P28482	MAPK1	S695	A702G	702	Missense	distal	7	no	17.547	17.434	EPSD	COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q969V6	MRTFA	P28482	MAPK1	S695	S695I	695	Missense	central	0	yes	17.547	0.000	EPSD	COSMIC	8.102	Loss
CMGC_MAPK_ERK1_MAPK1_ST	Q969V6	MRTFA	P28482	MAPK1	T781	P779L	779	Missense	proximal	-2	no	9.549	7.632	EPSD	COSMIC	8.102	Loss
CMGC_MAPK_ERK1_MAPK1_ST	Q969V6	MRTFA	P28482	MAPK1	T781	S785P	785	Missense	distal	4	no	9.549	9.560	EPSD	COSMIC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q969V6	MRTFA	P28482	MAPK1	T781	P779S	779	Missense	proximal	-2	no	9.549	6.715	EPSD	COSMIC	8.102	Loss
CMGC_MAPK_ERK1_MAPK1_ST	Q969V6	MRTFA	P28482	MAPK1	S785	P779L	779	Missense	distal	-6	no	11.357	11.265	EPSD	COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q969V6	MRTFA	P28482	MAPK1	S785	S785P	785	Missense	central	0	yes	11.357	0.000	EPSD	COSMIC	8.102	Loss
CMGC_MAPK_ERK1_MAPK1_ST	Q969V6	MRTFA	P28482	MAPK1	S785	P779S	779	Missense	distal	-6	no	11.357	11.331	EPSD	COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q969V6	MRTFA	P28482	MAPK1	S792	S785P	785	Missense	distal	-7	no	12.422	12.426	EPSD	COSMIC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q969V6	MRTFA	P28482	MAPK1	S807	R813C	813	Missense	distal	6	no	17.316	16.556	EPSD	COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q969V6	MRTFA	P28482	MAPK1	S807	P808T	808	Missense	proximal	1	no	17.316	8.817	EPSD	COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q969V6	MRTFA	P28482	MAPK1	S807	P805A	805	Missense	proximal	-2	no	17.316	14.169	EPSD	COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q969V6	MRTFA	P28482	MAPK1	S807	S809P	809	Missense	proximal	2	no	17.316	17.344	EPSD	COSMIC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q969V6	MRTFA	P28482	MAPK1	S807	P803L	803	Missense	distal	-4	no	17.316	17.012	EPSD	COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q969V6	MRTFA	P28482	MAPK1	S859	S859P	859	Missense	central	0	yes	17.849	0.000	EPSD	COSMIC	8.102	Loss
CMGC_MAPK_ERK1_MAPK1_ST	Q969V6	MRTFA	P28482	MAPK1	S859	H856R	856	Missense	distal	-3	no	17.849	18.178	EPSD	COSMIC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q969V6	MRTFA	P28482	MAPK1	S859	I853V	853	Missense	distal	-6	no	17.849	17.890	EPSD	COSMIC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q07889	SOS1	P28482	MAPK1	T200	V205L	205	Missense	distal	5	no	8.512	8.424	EPSD	COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q07889	SOS1	P28482	MAPK1	T200	S196L	196	Missense	distal	-4	no	8.512	8.292	EPSD	COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q07889	SOS1	P28482	MAPK1	S582	D581E	581	Missense	proximal	-1	no	9.039	9.079	EPSD	COSMIC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q07889	SOS1	P28482	MAPK1	S757	T753A	753	Missense	distal	-4	no	15.597	15.617	EPSD	COSMIC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q07889	SOS1	P28482	MAPK1	S818	E815K	815	Missense	distal	-3	no	14.069	13.991	EPSD	COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q07889	SOS1	P28482	MAPK1	S853	R854P	854	Missense	proximal	1	no	6.287	15.942	EPSD	COSMIC;GDSC;CCLE	8.102	Gain
CMGC_MAPK_ERK1_MAPK1_ST	Q07889	SOS1	P28482	MAPK1	T1054	P1060S	1060	Missense	distal	6	no	13.345	13.346	EPSD	COSMIC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q07889	SOS1	P28482	MAPK1	T1054	R1051G	1051	Missense	distal	-3	no	13.345	13.176	EPSD	COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q07889	SOS1	P28482	MAPK1	S1064	P1069S	1069	Missense	distal	5	no	8.454	8.472	EPSD	COSMIC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q07889	SOS1	P28482	MAPK1	S1064	R1067G	1067	Missense	distal	3	no	8.454	8.492	EPSD	COSMIC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q07889	SOS1	P28482	MAPK1	S1064	P1060S	1060	Missense	distal	-4	no	8.454	8.370	EPSD	COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q07889	SOS1	P28482	MAPK1	S1132	G1129V	1129	Missense	distal	-3	no	10.454	10.335	EPSD;PhosphoSitePlus	COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q07889	SOS1	P28482	MAPK1	S1161	P1154S	1154	Missense	distal	-7	no	9.015	9.011	EPSD	COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q07889	SOS1	P28482	MAPK1	S1178	P1179L	1179	Missense	proximal	1	no	13.573	4.763	EPSD;PhosphoSitePlus	COSMIC	8.102	Loss
CMGC_MAPK_ERK1_MAPK1_ST	Q07889	SOS1	P28482	MAPK1	S1178	P1183R	1183	Missense	distal	5	no	13.573	13.622	EPSD;PhosphoSitePlus	COSMIC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q07889	SOS1	P28482	MAPK1	S1178	P1184H	1184	Missense	distal	6	no	13.573	13.267	EPSD;PhosphoSitePlus	COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q07889	SOS1	P28482	MAPK1	S1193	D1200E	1200	Missense	distal	7	no	15.592	15.536	EPSD;PhosphoSitePlus	COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q07889	SOS1	P28482	MAPK1	S1210	P1212S	1212	Missense	proximal	2	no	17.240	17.212	EPSD	COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q07889	SOS1	P28482	MAPK1	S1210	S1205L	1205	Missense	distal	-5	no	17.240	17.315	EPSD	COSMIC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q07889	SOS1	P28482	MAPK1	S1210	P1215T	1215	Missense	distal	5	no	17.240	17.185	EPSD	COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q07889	SOS1	P28482	MAPK1	T1222	V1225A	1225	Missense	distal	3	no	14.025	14.046	EPSD	COSMIC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q07889	SOS1	P28482	MAPK1	T1222	P1216S	1216	Missense	distal	-6	no	14.025	13.999	EPSD	COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q07889	SOS1	P28482	MAPK1	T1222	P1215T	1215	Missense	distal	-7	no	14.025	14.008	EPSD	COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q07889	SOS1	P28482	MAPK1	S1229	V1225A	1225	Missense	distal	-4	no	14.269	14.329	EPSD	COSMIC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q07889	SOS1	P28482	MAPK1	S1229	P1230T	1230	Missense	proximal	1	no	14.269	5.770	EPSD	COSMIC	8.102	Loss
CMGC_MAPK_ERK1_MAPK1_ST	Q07889	SOS1	P28482	MAPK1	S1229	L1231V	1231	Missense	proximal	2	no	14.269	14.363	EPSD	COSMIC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q07889	SOS1	P28482	MAPK1	S1229	P1235T	1235	Missense	distal	6	no	14.269	14.059	EPSD	COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q07889	SOS1	P28482	MAPK1	S1252	P1250S	1250	Missense	proximal	-2	no	17.483	14.649	EPSD	COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q07889	SOS1	P28482	MAPK1	S1252	S1254P	1254	Missense	proximal	2	no	17.483	17.511	EPSD	COSMIC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q07889	SOS1	P28482	MAPK1	S1254	P1250S	1250	Missense	distal	-4	no	14.219	14.136	EPSD	COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q07889	SOS1	P28482	MAPK1	S1254	S1254P	1254	Missense	central	0	yes	14.219	0.000	EPSD	COSMIC	8.102	Loss
CMGC_MAPK_ERK1_MAPK1_ST	Q07889	SOS1	P28482	MAPK1	S1254	P1261L	1261	Missense	distal	7	no	14.219	14.519	EPSD	COSMIC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q07889	SOS1	P28482	MAPK1	T1257	P1250S	1250	Missense	distal	-7	no	15.601	15.596	EPSD	COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q07889	SOS1	P28482	MAPK1	T1257	S1254P	1254	Missense	distal	-3	no	15.601	15.777	EPSD	COSMIC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q07889	SOS1	P28482	MAPK1	T1257	P1261L	1261	Missense	distal	4	no	15.601	15.480	EPSD	COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q07889	SOS1	P28482	MAPK1	T1263	P1261L	1261	Missense	proximal	-2	no	18.139	16.222	EPSD	COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q07889	SOS1	P28482	MAPK1	S1265	P1261L	1261	Missense	distal	-4	no	15.480	15.176	EPSD	COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q07889	SOS1	P28482	MAPK1	S1275	P1276L	1276	Missense	proximal	1	no	15.309	6.499	EPSD	COSMIC	8.102	Loss
CMGC_MAPK_ERK1_MAPK1_ST	Q07889	SOS1	P28482	MAPK1	T1309	H1316Q	1316	Missense	distal	7	no	9.740	9.636	EPSD	COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q13614	MTMR2	P28482	MAPK1	S21	A28V	28	Missense	distal	7	no	8.628	8.730	EPSD	COSMIC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q13614	MTMR2	P28482	MAPK1	S21	A28T	28	Missense	distal	7	no	8.628	8.599	EPSD	COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q13614	MTMR2	P28482	MAPK1	S29	A28V	28	Missense	proximal	-1	no	8.462	8.473	EPSD	COSMIC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q13614	MTMR2	P28482	MAPK1	S29	A28T	28	Missense	proximal	-1	no	8.462	8.457	EPSD	COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q13614	MTMR2	P28482	MAPK1	S58	R62M	62	Missense	distal	4	no	13.641	13.476	PhosphoSitePlus	COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q13614	MTMR2	P28482	MAPK1	S58	D55N	55	Missense	distal	-3	no	13.641	13.609	PhosphoSitePlus	COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q13614	MTMR2	P28482	MAPK1	S58	V63I	63	Missense	distal	5	no	13.641	13.467	PhosphoSitePlus	COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q13614	MTMR2	P28482	MAPK1	S622	R621Q	621	Missense	proximal	-1	no	8.489	8.467	EPSD	COSMIC;GDSC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q13614	MTMR2	P28482	MAPK1	S622	A629T	629	Missense	distal	7	no	8.489	8.460	EPSD	COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q13614	MTMR2	P28482	MAPK1	S622	A629S	629	Missense	distal	7	no	8.489	8.308	EPSD	COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q13614	MTMR2	P28482	MAPK1	S626	R621Q	621	Missense	distal	-5	no	9.876	9.954	EPSD	COSMIC;GDSC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q13614	MTMR2	P28482	MAPK1	S626	A629T	629	Missense	distal	3	no	9.876	9.860	EPSD	COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q13614	MTMR2	P28482	MAPK1	S626	A629S	629	Missense	distal	3	no	9.876	9.867	EPSD	COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q13614	MTMR2	P28482	MAPK1	S631	A629T	629	Missense	proximal	-2	no	15.302	15.750	EPSD	COSMIC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q13614	MTMR2	P28482	MAPK1	S631	P638S	638	Missense	distal	7	no	15.302	15.313	EPSD	COSMIC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q13614	MTMR2	P28482	MAPK1	S631	A629S	629	Missense	proximal	-2	no	15.302	15.615	EPSD	COSMIC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q13614	MTMR2	P28482	MAPK1	T637	P638S	638	Missense	proximal	1	no	14.782	5.388	EPSD	COSMIC	8.102	Loss
CMGC_MAPK_ERK1_MAPK1_ST	Q13614	MTMR2	P28482	MAPK1	T637	Q640K	640	Missense	distal	3	no	14.782	14.712	EPSD	COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q96EP5	DAZAP1	P28482	MAPK1	T86	D81Y	81	Missense	distal	-5	no	15.831	15.966	EPSD	COSMIC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q96EP5	DAZAP1	P28482	MAPK1	T269	P270T	270	Missense	proximal	1	no	13.910	5.411	EPSD;PhosphoSitePlus	COSMIC	8.102	Loss
CMGC_MAPK_ERK1_MAPK1_ST	Q96EP5	DAZAP1	P28482	MAPK1	T269	G272S	272	Missense	distal	3	no	13.910	13.895	EPSD;PhosphoSitePlus	COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q96EP5	DAZAP1	P28482	MAPK1	T269	P276S	276	Missense	distal	7	no	13.910	13.921	EPSD;PhosphoSitePlus	COSMIC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q96EP5	DAZAP1	P28482	MAPK1	T315	G317R	317	Missense	proximal	2	no	17.191	17.286	PhosphoSitePlus;EPSD	COSMIC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q13322	GRB10	P28482	MAPK1	T23	K19R	19	Missense	distal	-4	no	15.860	15.782	EPSD	COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q13322	GRB10	P28482	MAPK1	T23	P24T	24	Missense	proximal	1	no	15.860	7.362	EPSD	COSMIC	8.102	Loss
CMGC_MAPK_ERK1_MAPK1_ST	Q13322	GRB10	P28482	MAPK1	T23	K19N	19	Missense	distal	-4	no	15.860	15.829	EPSD	COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q13322	GRB10	P28482	MAPK1	T23	D18E	18	Missense	distal	-5	no	15.860	15.816	EPSD	COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q13322	GRB10	P28482	MAPK1	T23	S26N	26	Missense	distal	3	no	15.860	15.782	EPSD	COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q13322	GRB10	P28482	MAPK1	T23	P30T	30	Missense	distal	7	no	15.860	16.023	EPSD	COSMIC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q13322	GRB10	P28482	MAPK1	S68	A69P	69	Missense	proximal	1	no	6.644	14.274	EPSD	COSMIC	8.102	Gain
CMGC_MAPK_ERK1_MAPK1_ST	Q13322	GRB10	P28482	MAPK1	S98	R91L	91	Missense	distal	-7	no	9.043	9.036	EPSD	COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q13322	GRB10	P28482	MAPK1	S98	R97L	97	Missense	proximal	-1	no	9.043	9.002	EPSD	COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q13322	GRB10	P28482	MAPK1	S98	Q102H	102	Missense	distal	4	no	9.043	8.976	EPSD	COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q13322	GRB10	P28482	MAPK1	S98	Q102L	102	Missense	distal	4	no	9.043	9.031	EPSD	COSMIC;GDSC;CCLE	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q13322	GRB10	P28482	MAPK1	S98	S98F	98	Missense	central	0	yes	9.043	0.000	EPSD	COSMIC	8.102	Loss
CMGC_MAPK_ERK1_MAPK1_ST	Q13322	GRB10	P28482	MAPK1	S98	P95S	95	Missense	distal	-3	no	9.043	8.866	EPSD	COSMIC;GDSC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q13322	GRB10	P28482	MAPK1	S104	R97L	97	Missense	distal	-7	no	13.383	13.375	EPSD	COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q13322	GRB10	P28482	MAPK1	S104	Q102H	102	Missense	proximal	-2	no	13.383	13.621	EPSD	COSMIC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q13322	GRB10	P28482	MAPK1	S104	R111C	111	Missense	distal	7	no	13.383	14.038	EPSD	COSMIC;CCLE	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q13322	GRB10	P28482	MAPK1	S104	R111P	111	Missense	distal	7	no	13.383	13.368	EPSD	COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q13322	GRB10	P28482	MAPK1	S104	Q102L	102	Missense	proximal	-2	no	13.383	14.459	EPSD	COSMIC;GDSC;CCLE	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q13322	GRB10	P28482	MAPK1	S104	S98F	98	Missense	distal	-6	no	13.383	13.298	EPSD	COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q13322	GRB10	P28482	MAPK1	S150	L154F	154	Missense	distal	4	no	16.768	16.700	PhosphoSitePlus;EPSD	COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q13322	GRB10	P28482	MAPK1	S150	P156L	156	Missense	distal	6	no	16.768	16.361	PhosphoSitePlus;EPSD	COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q13322	GRB10	P28482	MAPK1	S150	P151H	151	Missense	proximal	1	no	16.768	8.944	PhosphoSitePlus;EPSD	COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q13322	GRB10	P28482	MAPK1	S150	P151S	151	Missense	proximal	1	no	16.768	7.373	PhosphoSitePlus;EPSD	COSMIC	8.102	Loss
CMGC_MAPK_ERK1_MAPK1_ST	Q13322	GRB10	P28482	MAPK1	T155	P156S	156	Missense	proximal	1	no	12.625	3.230	EPSD	COSMIC	8.102	Loss
CMGC_MAPK_ERK1_MAPK1_ST	Q13322	GRB10	P28482	MAPK1	T155	L154F	154	Missense	proximal	-1	no	12.625	12.595	EPSD	COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q13322	GRB10	P28482	MAPK1	T155	S158F	158	Missense	distal	3	no	12.625	12.687	EPSD	COSMIC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q13322	GRB10	P28482	MAPK1	T155	P156L	156	Missense	proximal	1	no	12.625	3.815	EPSD	COSMIC	8.102	Loss
CMGC_MAPK_ERK1_MAPK1_ST	Q13322	GRB10	P28482	MAPK1	T155	P151H	151	Missense	distal	-4	no	12.625	12.383	EPSD	COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q13322	GRB10	P28482	MAPK1	T155	P151S	151	Missense	distal	-4	no	12.625	12.541	EPSD	COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q13322	GRB10	P28482	MAPK1	S418	L416F	416	Missense	proximal	-2	no	16.613	15.890	EPSD	COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q13322	GRB10	P28482	MAPK1	S418	V424L	424	Missense	distal	6	no	16.613	16.421	EPSD	COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q13322	GRB10	P28482	MAPK1	S418	A415T	415	Missense	distal	-3	no	16.613	16.770	EPSD	COSMIC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q13322	GRB10	P28482	MAPK1	S421	V427L	427	Missense	distal	6	no	8.588	8.397	EPSD	COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q13322	GRB10	P28482	MAPK1	S421	L416F	416	Missense	distal	-5	no	8.588	8.602	EPSD	COSMIC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q13322	GRB10	P28482	MAPK1	S421	V424L	424	Missense	distal	3	no	8.588	8.621	EPSD	COSMIC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q13322	GRB10	P28482	MAPK1	S421	A415T	415	Missense	distal	-6	no	8.588	8.578	EPSD	COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q13322	GRB10	P28482	MAPK1	T422	V427L	427	Missense	distal	5	no	13.463	13.375	EPSD	COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q13322	GRB10	P28482	MAPK1	T422	L416F	416	Missense	distal	-6	no	13.463	13.445	EPSD	COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q13322	GRB10	P28482	MAPK1	T422	V424L	424	Missense	proximal	2	no	13.463	13.369	EPSD	COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q13322	GRB10	P28482	MAPK1	T422	A415T	415	Missense	distal	-7	no	13.463	13.449	EPSD	COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q13322	GRB10	P28482	MAPK1	S476	L472F	472	Missense	distal	-4	no	13.998	13.958	EPSD;PhosphoSitePlus	COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q13322	GRB10	P28482	MAPK1	S476	L478F	478	Missense	proximal	2	no	13.998	13.986	EPSD;PhosphoSitePlus	COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q13322	GRB10	P28482	MAPK1	S476	S476N	476	Missense	central	0	yes	13.998	0.000	EPSD;PhosphoSitePlus	COSMIC	8.102	Loss
CMGC_MAPK_ERK1_MAPK1_ST	O95600	KLF8	P28482	MAPK1	S48	S44N	44	Missense	distal	-4	no	12.489	12.530	PhosphoSitePlus	COSMIC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	O95600	KLF8	P28482	MAPK1	S48	D53N	53	Missense	distal	5	no	12.489	12.391	PhosphoSitePlus	COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	O95600	KLF8	P28482	MAPK1	S48	S44R	44	Missense	distal	-4	no	12.489	12.483	PhosphoSitePlus	COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	O95600	KLF8	P28482	MAPK1	S342	R341H	341	Missense	proximal	-1	no	10.183	10.159	EPSD	COSMIC;GDSC;CCLE	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	O95600	KLF8	P28482	MAPK1	S342	C339S	339	Missense	distal	-3	no	10.183	10.710	EPSD	COSMIC;GDSC;CCLE	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P84022	SMAD3	P28482	MAPK1	T8	P9L	9	Missense	proximal	1	no	15.702	6.893	EPSD	COSMIC	8.102	Loss
CMGC_MAPK_ERK1_MAPK1_ST	P84022	SMAD3	P28482	MAPK1	T8	I4V	4	Missense	distal	-4	no	15.702	16.019	EPSD	COSMIC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P84022	SMAD3	P28482	MAPK1	T132	H126R	126	Missense	distal	-6	no	13.028	13.111	EPSD	COSMIC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P84022	SMAD3	P28482	MAPK1	T132	P137L	137	Missense	distal	5	no	13.028	12.815	EPSD	COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P84022	SMAD3	P28482	MAPK1	T132	V134A	134	Missense	proximal	2	no	13.028	12.952	EPSD	COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P84022	SMAD3	P28482	MAPK1	T132	V138L	138	Missense	distal	6	no	13.028	12.836	EPSD	COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P84022	SMAD3	P28482	MAPK1	T132	P136R	136	Missense	distal	4	no	13.028	12.995	EPSD	COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P84022	SMAD3	P28482	MAPK1	T132	P133L	133	Missense	proximal	1	no	13.028	4.218	EPSD	COSMIC	8.102	Loss
CMGC_MAPK_ERK1_MAPK1_ST	P84022	SMAD3	P28482	MAPK1	T179	N175D	175	Missense	distal	-4	no	14.377	14.406	EPSD;PhosphoSitePlus	COSMIC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P84022	SMAD3	P28482	MAPK1	T179	P182S	182	Missense	distal	3	no	14.377	14.447	EPSD;PhosphoSitePlus	COSMIC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P84022	SMAD3	P28482	MAPK1	T179	P177L	177	Missense	proximal	-2	no	14.377	12.460	EPSD;PhosphoSitePlus	COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P84022	SMAD3	P28482	MAPK1	T179	P172H	172	Missense	distal	-7	no	14.377	14.361	EPSD;PhosphoSitePlus	COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P84022	SMAD3	P28482	MAPK1	S204	S204N	204	Missense	central	0	yes	14.774	0.000	EPSD;PhosphoSitePlus	COSMIC	8.102	Loss
CMGC_MAPK_ERK1_MAPK1_ST	P84022	SMAD3	P28482	MAPK1	S204	P211S	211	Missense	distal	7	no	14.774	14.785	EPSD;PhosphoSitePlus	COSMIC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P84022	SMAD3	P28482	MAPK1	S204	A202T	202	Missense	proximal	-2	no	14.774	15.221	EPSD;PhosphoSitePlus	COSMIC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P84022	SMAD3	P28482	MAPK1	S204	S204F	204	Missense	central	0	yes	14.774	0.000	EPSD;PhosphoSitePlus	COSMIC	8.102	Loss
CMGC_MAPK_ERK1_MAPK1_ST	P84022	SMAD3	P28482	MAPK1	S204	P211L	211	Missense	distal	7	no	14.774	15.073	EPSD;PhosphoSitePlus	COSMIC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P84022	SMAD3	P28482	MAPK1	S204	P209S	209	Missense	distal	5	no	14.774	14.792	EPSD;PhosphoSitePlus	COSMIC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P84022	SMAD3	P28482	MAPK1	S208	S204N	204	Missense	distal	-4	no	16.481	16.522	PhosphoSitePlus;EPSD	COSMIC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P84022	SMAD3	P28482	MAPK1	S208	P211S	211	Missense	distal	3	no	16.481	16.550	PhosphoSitePlus;EPSD	COSMIC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P84022	SMAD3	P28482	MAPK1	S208	A202T	202	Missense	distal	-6	no	16.481	16.470	PhosphoSitePlus;EPSD	COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P84022	SMAD3	P28482	MAPK1	S208	S204F	204	Missense	distal	-4	no	16.481	16.220	PhosphoSitePlus;EPSD	COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P84022	SMAD3	P28482	MAPK1	S208	P211L	211	Missense	distal	3	no	16.481	16.570	PhosphoSitePlus;EPSD	COSMIC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P84022	SMAD3	P28482	MAPK1	S208	P209S	209	Missense	proximal	1	no	16.481	7.086	PhosphoSitePlus;EPSD	COSMIC	8.102	Loss
CMGC_MAPK_ERK1_MAPK1_ST	P84022	SMAD3	P28482	MAPK1	S213	P211S	211	Missense	proximal	-2	no	19.707	16.873	EPSD;PhosphoSitePlus	COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P84022	SMAD3	P28482	MAPK1	S213	P211L	211	Missense	proximal	-2	no	19.707	17.790	EPSD;PhosphoSitePlus	COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P84022	SMAD3	P28482	MAPK1	S213	P209S	209	Missense	distal	-4	no	19.707	19.623	EPSD;PhosphoSitePlus	COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P84022	SMAD3	P28482	MAPK1	T286	R287P	287	Missense	proximal	1	no	3.301	12.955	EPSD	COSMIC	8.102	Gain
CMGC_MAPK_ERK1_MAPK1_ST	P84022	SMAD3	P28482	MAPK1	T412	D408Y	408	Missense	distal	-4	no	9.466	8.807	EPSD	COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P84022	SMAD3	P28482	MAPK1	T412	L407P	407	Missense	distal	-5	no	9.466	9.317	EPSD	COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P84022	SMAD3	P28482	MAPK1	T412	V410I	410	Missense	proximal	-2	no	9.466	9.444	EPSD	COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P84022	SMAD3	P28482	MAPK1	S416	S423G	423	Missense	distal	7	no	12.685	12.754	EPSD	COSMIC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P84022	SMAD3	P28482	MAPK1	S416	S423I	423	Missense	distal	7	no	12.685	13.233	EPSD	COSMIC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P84022	SMAD3	P28482	MAPK1	S416	V410I	410	Missense	distal	-6	no	12.685	12.644	EPSD	COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P84022	SMAD3	P28482	MAPK1	S416	S422Y	422	Missense	distal	6	no	12.685	12.067	EPSD	COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P84022	SMAD3	P28482	MAPK1	S416	C421Y	421	Missense	distal	5	no	12.685	12.797	EPSD	COSMIC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P84022	SMAD3	P28482	MAPK1	S416	R420C	420	Missense	distal	4	no	12.685	12.426	EPSD	COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q9NZ72	STMN3	P28482	MAPK1	S60	D63H	63	Missense	distal	3	no	14.667	14.669	EPSD	COSMIC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q9NZ72	STMN3	P28482	MAPK1	S60	D63N	63	Missense	distal	3	no	14.667	14.571	EPSD	COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q9NZ72	STMN3	P28482	MAPK1	S60	D63E	63	Missense	distal	3	no	14.667	14.571	EPSD	COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q9NZ72	STMN3	P28482	MAPK1	S60	E55K	55	Missense	distal	-5	no	14.667	14.644	EPSD	COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q9NZ72	STMN3	P28482	MAPK1	S65	P69H	69	Missense	distal	4	no	14.438	14.263	EPSD	COSMIC;GDSC;CCLE	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q9NZ72	STMN3	P28482	MAPK1	S65	D63H	63	Missense	proximal	-2	no	14.438	14.985	EPSD	COSMIC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q9NZ72	STMN3	P28482	MAPK1	S65	D63N	63	Missense	proximal	-2	no	14.438	14.920	EPSD	COSMIC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q9NZ72	STMN3	P28482	MAPK1	S65	D63E	63	Missense	proximal	-2	no	14.438	15.361	EPSD	COSMIC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q9NZ72	STMN3	P28482	MAPK1	S65	S72F	72	Missense	distal	7	no	14.438	14.786	EPSD	COSMIC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q9NZ72	STMN3	P28482	MAPK1	S68	P69H	69	Missense	proximal	1	no	16.119	8.295	PhosphoSitePlus	COSMIC;GDSC;CCLE	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q9NZ72	STMN3	P28482	MAPK1	S68	D63H	63	Missense	distal	-5	no	16.119	16.173	PhosphoSitePlus	COSMIC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q9NZ72	STMN3	P28482	MAPK1	S68	D63N	63	Missense	distal	-5	no	16.119	16.074	PhosphoSitePlus	COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q9NZ72	STMN3	P28482	MAPK1	S68	D63E	63	Missense	distal	-5	no	16.119	16.074	PhosphoSitePlus	COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q9NZ72	STMN3	P28482	MAPK1	S68	S72F	72	Missense	distal	4	no	16.119	15.941	PhosphoSitePlus	COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q9NZ72	STMN3	P28482	MAPK1	S73	P69H	69	Missense	distal	-4	no	15.549	15.308	EPSD	COSMIC;GDSC;CCLE	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q9NZ72	STMN3	P28482	MAPK1	S73	S72F	72	Missense	proximal	-1	no	15.549	15.503	EPSD	COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q96I25	RBM17	P28482	MAPK1	S48	T45M	45	Missense	distal	-3	no	8.317	8.089	EPSD	COSMIC	8.102	Loss
CMGC_MAPK_ERK1_MAPK1_ST	Q96I25	RBM17	P28482	MAPK1	S48	S48G	48	Missense	central	0	yes	8.317	0.000	EPSD	COSMIC	8.102	Loss
CMGC_MAPK_ERK1_MAPK1_ST	Q96I25	RBM17	P28482	MAPK1	T71	R66Q	66	Missense	distal	-5	no	14.334	14.411	EPSD;PhosphoSitePlus	COSMIC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q96I25	RBM17	P28482	MAPK1	T71	D65E	65	Missense	distal	-6	no	14.334	14.321	EPSD;PhosphoSitePlus	COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q96I25	RBM17	P28482	MAPK1	S222	S229F	229	Missense	distal	7	no	17.979	18.326	PhosphoSitePlus;EPSD	COSMIC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q96I25	RBM17	P28482	MAPK1	S222	G225R	225	Missense	distal	3	no	17.979	17.941	PhosphoSitePlus;EPSD	COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P12980	LYL1	P28482	MAPK1	S25	P32A	32	Missense	distal	7	no	14.308	14.500	EPSD	COSMIC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P12980	LYL1	P28482	MAPK1	S25	S25N	25	Missense	central	0	yes	14.308	0.000	EPSD	COSMIC	8.102	Loss
CMGC_MAPK_ERK1_MAPK1_ST	P12980	LYL1	P28482	MAPK1	S36	E43K	43	Missense	distal	7	no	17.074	17.082	PhosphoSitePlus	COSMIC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P12980	LYL1	P28482	MAPK1	S36	P32A	32	Missense	distal	-4	no	17.074	16.781	PhosphoSitePlus	COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P12980	LYL1	P28482	MAPK1	S36	A35D	35	Missense	proximal	-1	no	17.074	17.056	PhosphoSitePlus	COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P12980	LYL1	P28482	MAPK1	S52	V45A	45	Missense	distal	-7	no	14.251	14.267	EPSD	COSMIC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P12980	LYL1	P28482	MAPK1	S134	E137D	137	Missense	distal	3	no	9.127	9.223	EPSD	COSMIC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P12980	LYL1	P28482	MAPK1	S134	R131W	131	Missense	distal	-3	no	9.127	8.429	EPSD	COSMIC;GDSC;CCLE	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P12980	LYL1	P28482	MAPK1	S134	E137K	137	Missense	distal	3	no	9.127	9.134	EPSD	COSMIC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P12980	LYL1	P28482	MAPK1	S134	R131Q	131	Missense	distal	-3	no	9.127	8.850	EPSD	COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P12980	LYL1	P28482	MAPK1	S134	A141V	141	Missense	distal	7	no	9.127	9.229	EPSD	COSMIC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P12980	LYL1	P28482	MAPK1	S260	D256N	256	Missense	distal	-4	no	16.315	16.287	EPSD	COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P12980	LYL1	P28482	MAPK1	S276	L275F	275	Missense	proximal	-1	no	15.862	15.832	EPSD	COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P51812	RPS6KA3	P28482	MAPK1	S78	G75R	75	Missense	distal	-3	no	8.042	8.211	EPSD	COSMIC	8.102	Gain
CMGC_MAPK_ERK1_MAPK1_ST	P51812	RPS6KA3	P28482	MAPK1	S227	Y234D	234	Missense	distal	7	no	10.418	9.897	EPSD	COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P51812	RPS6KA3	P28482	MAPK1	S227	K223N	223	Missense	distal	-4	no	10.418	10.387	EPSD	COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P51812	RPS6KA3	P28482	MAPK1	T354	G349C	349	Missense	distal	-5	no	8.461	8.670	EPSD	COSMIC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P51812	RPS6KA3	P28482	MAPK1	T354	D353Y	353	Missense	proximal	-1	no	8.461	8.441	EPSD	COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P51812	RPS6KA3	P28482	MAPK1	T365	T362A	362	Missense	distal	-3	no	13.775	13.617	EPSD	COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P51812	RPS6KA3	P28482	MAPK1	S369	T362A	362	Missense	distal	-7	no	15.616	15.631	EPSD	COSMIC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P51812	RPS6KA3	P28482	MAPK1	T577	M576R	576	Missense	proximal	-1	no	15.244	15.274	EPSD	COSMIC;CCLE	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P51812	RPS6KA3	P28482	MAPK1	T625	P626Q	626	Missense	proximal	1	no	10.201	1.707	EPSD	COSMIC	8.102	Loss
CMGC_MAPK_ERK1_MAPK1_ST	P51812	RPS6KA3	P28482	MAPK1	T625	L630F	630	Missense	distal	5	no	10.201	10.235	EPSD	COSMIC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P51812	RPS6KA3	P28482	MAPK1	T625	E628K	628	Missense	distal	3	no	10.201	10.208	EPSD	COSMIC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P51812	RPS6KA3	P28482	MAPK1	S715	L718W	718	Missense	distal	3	no	14.509	14.614	EPSD	COSMIC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P51812	RPS6KA3	P28482	MAPK1	T725	L718W	718	Missense	distal	-7	no	10.124	10.080	EPSD	COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P08047	SP1	P28482	MAPK1	S59	S59Y	59	Missense	central	0	yes	13.407	0.000	PhosphoSitePlus;EPSD	COSMIC	8.102	Loss
CMGC_MAPK_ERK1_MAPK1_ST	P08047	SP1	P28482	MAPK1	S73	E72K	72	Missense	proximal	-1	no	13.859	13.887	EPSD	COSMIC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P08047	SP1	P28482	MAPK1	S73	N79K	79	Missense	distal	6	no	13.859	14.012	EPSD	COSMIC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P08047	SP1	P28482	MAPK1	T278	T278M	278	Missense	central	0	yes	12.616	0.000	EPSD	COSMIC	8.102	Loss
CMGC_MAPK_ERK1_MAPK1_ST	P08047	SP1	P28482	MAPK1	T453	P458H	458	Missense	distal	5	no	12.721	12.594	EPSD;PhosphoSitePlus	COSMIC;GDSC;CCLE	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P08047	SP1	P28482	MAPK1	T453	R452W	452	Missense	proximal	-1	no	12.721	12.620	EPSD;PhosphoSitePlus	COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P08047	SP1	P28482	MAPK1	T739	T739P	739	Missense	central	0	yes	13.402	0.000	EPSD;PhosphoSitePlus	COSMIC	8.102	Loss
CMGC_MAPK_ERK1_MAPK1_ST	P08047	SP1	P28482	MAPK1	T739	T746P	746	Missense	distal	7	no	13.402	13.239	EPSD;PhosphoSitePlus	COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P08047	SP1	P28482	MAPK1	T739	S732L	732	Missense	distal	-7	no	13.402	13.394	EPSD;PhosphoSitePlus	COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P08047	SP1	P28482	MAPK1	T745	T746P	746	Missense	proximal	1	no	6.362	14.861	EPSD	COSMIC	8.102	Gain
CMGC_MAPK_ERK1_MAPK1_ST	P55211	CASP9	P28482	MAPK1	S87	S87L	87	Missense	central	0	yes	9.260	0.000	EPSD	COSMIC;GDSC;CCLE	8.102	Loss
CMGC_MAPK_ERK1_MAPK1_ST	P55211	CASP9	P28482	MAPK1	S87	R90H	90	Missense	distal	3	no	9.260	9.303	EPSD	COSMIC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P55211	CASP9	P28482	MAPK1	T107	T107A	107	Missense	central	0	yes	14.563	0.000	EPSD	COSMIC	8.102	Loss
CMGC_MAPK_ERK1_MAPK1_ST	P55211	CASP9	P28482	MAPK1	T107	V109L	109	Missense	proximal	2	no	14.563	14.469	EPSD	COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P55211	CASP9	P28482	MAPK1	T125	T125P	125	Missense	central	0	yes	15.221	0.000	PhosphoSitePlus	COSMIC	8.102	Loss
CMGC_MAPK_ERK1_MAPK1_ST	P55211	CASP9	P28482	MAPK1	S302	E297G	297	Missense	distal	-5	no	15.851	15.894	EPSD	COSMIC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P55211	CASP9	P28482	MAPK1	S302	G295V	295	Missense	distal	-7	no	15.851	15.850	EPSD	COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P55211	CASP9	P28482	MAPK1	S307	S310I	310	Missense	distal	3	no	12.776	12.834	EPSD	COSMIC;CCLE	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P55211	CASP9	P28482	MAPK1	T317	P318S	318	Missense	proximal	1	no	14.049	4.654	EPSD	COSMIC	8.102	Loss
CMGC_MAPK_ERK1_MAPK1_ST	P55211	CASP9	P28482	MAPK1	T317	S310I	310	Missense	distal	-7	no	14.049	14.022	EPSD	COSMIC;CCLE	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q16828	DUSP6	P28482	MAPK1	S159	G166V	166	Missense	distal	7	no	13.542	13.756	PhosphoSitePlus;EPSD	COSMIC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q16828	DUSP6	P28482	MAPK1	S159	C155R	155	Missense	distal	-4	no	13.542	14.180	PhosphoSitePlus;EPSD	COSMIC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q16828	DUSP6	P28482	MAPK1	S159	L165F	165	Missense	distal	6	no	13.542	13.508	PhosphoSitePlus;EPSD	COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q16828	DUSP6	P28482	MAPK1	S197	T192A	192	Missense	distal	-5	no	14.950	14.972	EPSD;PhosphoSitePlus	COSMIC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q16828	DUSP6	P28482	MAPK1	S197	P198L	198	Missense	proximal	1	no	14.950	6.140	EPSD;PhosphoSitePlus	COSMIC	8.102	Loss
CMGC_MAPK_ERK1_MAPK1_ST	Q16828	DUSP6	P28482	MAPK1	S197	D193Y	193	Missense	distal	-4	no	14.950	14.292	EPSD;PhosphoSitePlus	COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q16828	DUSP6	P28482	MAPK1	S197	S190L	190	Missense	distal	-7	no	14.950	14.942	EPSD;PhosphoSitePlus	COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q16828	DUSP6	P28482	MAPK1	S197	D193H	193	Missense	distal	-4	no	14.950	14.723	EPSD;PhosphoSitePlus	COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q16828	DUSP6	P28482	MAPK1	S205	P198L	198	Missense	distal	-7	no	8.150	8.137	EPSD	COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q16828	DUSP6	P28482	MAPK1	S205	P207Q	207	Missense	proximal	2	no	8.150	7.972	EPSD	COSMIC	8.102	Loss
CMGC_MAPK_ERK1_MAPK1_ST	Q16828	DUSP6	P28482	MAPK1	S205	P212L	212	Missense	distal	7	no	8.150	8.449	EPSD	COSMIC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q16828	DUSP6	P28482	MAPK1	S331	G338S	338	Missense	distal	7	no	13.425	13.356	EPSD	COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q16828	DUSP6	P28482	MAPK1	S331	M325L	325	Missense	distal	-6	no	13.425	13.417	EPSD	COSMIC;CCLE	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q16828	DUSP6	P28482	MAPK1	S331	M337L	337	Missense	distal	6	no	13.425	13.451	EPSD	COSMIC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q16828	DUSP6	P28482	MAPK1	S351	P358L	358	Missense	distal	7	no	15.140	15.439	EPSD	COSMIC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q9Y6W5	WASF2	P28482	MAPK1	T129	N134K	134	Missense	distal	5	no	12.926	12.895	EPSD	COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q9Y6W5	WASF2	P28482	MAPK1	T137	N134K	134	Missense	distal	-3	no	12.338	12.242	EPSD	COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q9Y6W5	WASF2	P28482	MAPK1	S257	P260S	260	Missense	distal	3	no	14.282	14.351	EPSD	COSMIC;CCLE	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q9Y6W5	WASF2	P28482	MAPK1	S257	S261F	261	Missense	distal	4	no	14.282	14.104	EPSD	COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q9Y6W5	WASF2	P28482	MAPK1	S257	E264K	264	Missense	distal	7	no	14.282	14.289	EPSD	COSMIC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q9Y6W5	WASF2	P28482	MAPK1	S259	P260S	260	Missense	proximal	1	no	14.368	4.973	EPSD	COSMIC;CCLE	8.102	Loss
CMGC_MAPK_ERK1_MAPK1_ST	Q9Y6W5	WASF2	P28482	MAPK1	S259	S261F	261	Missense	proximal	2	no	14.368	14.237	EPSD	COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q9Y6W5	WASF2	P28482	MAPK1	S259	E264K	264	Missense	distal	5	no	14.368	14.309	EPSD	COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q9Y6W5	WASF2	P28482	MAPK1	S296	P302T	302	Missense	distal	6	no	16.752	16.541	EPSD;PhosphoSitePlus	COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q9Y6W5	WASF2	P28482	MAPK1	S296	R291G	291	Missense	distal	-5	no	16.752	16.772	EPSD;PhosphoSitePlus	COSMIC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q9Y6W5	WASF2	P28482	MAPK1	S308	P302T	302	Missense	distal	-6	no	16.283	16.233	PhosphoSitePlus;EPSD	COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q9Y6W5	WASF2	P28482	MAPK1	S308	G315R	315	Missense	distal	7	no	16.283	16.218	PhosphoSitePlus;EPSD	COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q9Y6W5	WASF2	P28482	MAPK1	S428	S429F	429	Missense	proximal	1	no	7.165	9.991	EPSD	COSMIC	8.102	Gain
CMGC_MAPK_ERK1_MAPK1_ST	O94953	KDM4B	P28482	MAPK1	S352	W358C	358	Missense	distal	6	no	15.356	15.519	PhosphoSitePlus;EPSD	COSMIC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	O94953	KDM4B	P28482	MAPK1	S352	A349V	349	Missense	distal	-3	no	15.356	15.416	PhosphoSitePlus;EPSD	COSMIC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	O94953	KDM4B	P28482	MAPK1	S352	T345K	345	Missense	distal	-7	no	15.356	15.372	PhosphoSitePlus;EPSD	COSMIC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	O94953	KDM4B	P28482	MAPK1	S352	R346Q	346	Missense	distal	-6	no	15.356	15.333	PhosphoSitePlus;EPSD	COSMIC;GDSC;CCLE	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	O94953	KDM4B	P28482	MAPK1	S566	P559S	559	Missense	distal	-7	no	17.766	17.762	EPSD;PhosphoSitePlus	COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	O94953	KDM4B	P28482	MAPK1	S566	P559L	559	Missense	distal	-7	no	17.766	17.754	EPSD;PhosphoSitePlus	COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	O94953	KDM4B	P28482	MAPK1	S622	R617Q	617	Missense	distal	-5	no	15.025	15.102	EPSD;PhosphoSitePlus	COSMIC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	O94953	KDM4B	P28482	MAPK1	S638	A631S	631	Missense	distal	-7	no	13.511	13.509	EPSD	COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	O94953	KDM4B	P28482	MAPK1	T1065	A1058T	1058	Missense	distal	-7	no	14.614	14.600	EPSD;PhosphoSitePlus	COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	O94953	KDM4B	P28482	MAPK1	T1065	D1071V	1071	Missense	distal	6	no	14.614	14.445	EPSD;PhosphoSitePlus	COSMIC;CCLE	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q15788	NCOA1	P28482	MAPK1	S325	F330L	330	Missense	distal	5	no	16.048	16.014	EPSD	COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q15788	NCOA1	P28482	MAPK1	S325	R320C	320	Missense	distal	-5	no	16.048	16.278	EPSD	COSMIC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q15788	NCOA1	P28482	MAPK1	S325	S327F	327	Missense	proximal	2	no	16.048	15.917	EPSD	COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q15788	NCOA1	P28482	MAPK1	S325	P326L	326	Missense	proximal	1	no	16.048	7.238	EPSD	COSMIC	8.102	Loss
CMGC_MAPK_ERK1_MAPK1_ST	Q15788	NCOA1	P28482	MAPK1	S372	P373S	373	Missense	proximal	1	no	15.125	5.730	EPSD	COSMIC;GDSC;CCLE	8.102	Loss
CMGC_MAPK_ERK1_MAPK1_ST	Q15788	NCOA1	P28482	MAPK1	S372	D365N	365	Missense	distal	-7	no	15.125	15.126	EPSD	COSMIC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q15788	NCOA1	P28482	MAPK1	S372	S372G	372	Missense	central	0	yes	15.125	0.000	EPSD	COSMIC	8.102	Loss
CMGC_MAPK_ERK1_MAPK1_ST	Q15788	NCOA1	P28482	MAPK1	S517	S523G	523	Missense	distal	6	no	15.224	15.146	EPSD	COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q15788	NCOA1	P28482	MAPK1	S558	S557I	557	Missense	proximal	-1	no	13.320	13.298	EPSD	COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q15788	NCOA1	P28482	MAPK1	S679	G674S	674	Missense	distal	-5	no	9.807	9.814	EPSD	COSMIC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q15788	NCOA1	P28482	MAPK1	S679	S682L	682	Missense	distal	3	no	9.807	9.828	EPSD	COSMIC;GDSC;CCLE	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q15788	NCOA1	P28482	MAPK1	S679	P677L	677	Missense	proximal	-2	no	9.807	7.890	EPSD	COSMIC	8.102	Loss
CMGC_MAPK_ERK1_MAPK1_ST	Q15788	NCOA1	P28482	MAPK1	S698	R692W	692	Missense	distal	-6	no	14.664	14.444	EPSD	COSMIC;GDSC;CCLE	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q15788	NCOA1	P28482	MAPK1	T789	P790S	790	Missense	proximal	1	no	14.030	4.635	EPSD	COSMIC	8.102	Loss
CMGC_MAPK_ERK1_MAPK1_ST	Q15788	NCOA1	P28482	MAPK1	T979	T979M	979	Missense	central	0	yes	12.582	0.000	EPSD	COSMIC;GDSC;CCLE	8.102	Loss
CMGC_MAPK_ERK1_MAPK1_ST	Q15788	NCOA1	P28482	MAPK1	T979	E986K	986	Missense	distal	7	no	12.582	12.589	EPSD	COSMIC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q15788	NCOA1	P28482	MAPK1	T979	M984K	984	Missense	distal	5	no	12.582	12.683	EPSD	COSMIC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q15788	NCOA1	P28482	MAPK1	S997	S999T	999	Missense	proximal	2	no	15.203	15.180	EPSD	COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q15788	NCOA1	P28482	MAPK1	S997	Y995H	995	Missense	proximal	-2	no	15.203	14.565	EPSD	COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q15788	NCOA1	P28482	MAPK1	S997	Y991N	991	Missense	distal	-6	no	15.203	15.320	EPSD	COSMIC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q15788	NCOA1	P28482	MAPK1	S997	P994S	994	Missense	distal	-3	no	15.203	15.026	EPSD	COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q15788	NCOA1	P28482	MAPK1	S999	Y995H	995	Missense	distal	-4	no	14.126	14.557	EPSD	COSMIC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q15788	NCOA1	P28482	MAPK1	S999	P994S	994	Missense	distal	-5	no	14.126	14.200	EPSD	COSMIC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q15788	NCOA1	P28482	MAPK1	S1006	R1013S	1013	Missense	distal	7	no	12.901	12.898	EPSD	COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q15788	NCOA1	P28482	MAPK1	S1006	S999T	999	Missense	distal	-7	no	12.901	12.889	EPSD	COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q15788	NCOA1	P28482	MAPK1	T1026	T1020A	1020	Missense	distal	-6	no	14.567	14.577	EPSD	COSMIC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q15788	NCOA1	P28482	MAPK1	T1026	M1021T	1021	Missense	distal	-5	no	14.567	14.517	EPSD	COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q15788	NCOA1	P28482	MAPK1	T1026	R1029G	1029	Missense	distal	3	no	14.567	14.605	EPSD	COSMIC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q15788	NCOA1	P28482	MAPK1	S1033	R1029G	1029	Missense	distal	-4	no	13.749	13.488	EPSD	COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q15788	NCOA1	P28482	MAPK1	T1099	N1105S	1105	Missense	distal	6	no	11.503	11.599	EPSD	COSMIC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q15788	NCOA1	P28482	MAPK1	T1099	P1100L	1100	Missense	proximal	1	no	11.503	2.693	EPSD	COSMIC	8.102	Loss
CMGC_MAPK_ERK1_MAPK1_ST	Q15788	NCOA1	P28482	MAPK1	T1099	P1100T	1100	Missense	proximal	1	no	11.503	3.004	EPSD	COSMIC	8.102	Loss
CMGC_MAPK_ERK1_MAPK1_ST	Q15788	NCOA1	P28482	MAPK1	T1099	P1100H	1100	Missense	proximal	1	no	11.503	3.679	EPSD	COSMIC	8.102	Loss
CMGC_MAPK_ERK1_MAPK1_ST	Q15788	NCOA1	P28482	MAPK1	T1179	T1175K	1175	Missense	distal	-4	no	16.029	16.332	PhosphoSitePlus;EPSD	COSMIC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q15788	NCOA1	P28482	MAPK1	T1179	T1175M	1175	Missense	distal	-4	no	16.029	15.877	PhosphoSitePlus;EPSD	COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q15788	NCOA1	P28482	MAPK1	S1250	P1251H	1251	Missense	proximal	1	no	13.971	6.147	EPSD	COSMIC	8.102	Loss
CMGC_MAPK_ERK1_MAPK1_ST	Q15788	NCOA1	P28482	MAPK1	S1250	P1251L	1251	Missense	proximal	1	no	13.971	5.161	EPSD	COSMIC	8.102	Loss
CMGC_MAPK_ERK1_MAPK1_ST	Q15788	NCOA1	P28482	MAPK1	S1250	N1244S	1244	Missense	distal	-6	no	13.971	13.967	EPSD	COSMIC;GDSC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q15788	NCOA1	P28482	MAPK1	T1271	P1272S	1272	Missense	proximal	1	no	14.120	4.725	EPSD	COSMIC	8.102	Loss
CMGC_MAPK_ERK1_MAPK1_ST	Q15788	NCOA1	P28482	MAPK1	S1279	P1272S	1272	Missense	distal	-7	no	14.789	14.785	EPSD	COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q15788	NCOA1	P28482	MAPK1	T1426	P1420L	1420	Missense	distal	-6	no	19.438	19.346	EPSD	COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P09917	ALOX5	P28482	MAPK1	S664	P669L	669	Missense	distal	5	no	16.483	16.270	PhosphoSitePlus	COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P13591	NCAM1	P28482	MAPK1	S613	P607Q	607	Missense	distal	-6	no	8.222	8.207	EPSD	COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P13591	NCAM1	P28482	MAPK1	S613	E611K	611	Missense	proximal	-2	no	8.222	8.182	EPSD	COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P13591	NCAM1	P28482	MAPK1	S613	P612T	612	Missense	proximal	-1	no	8.222	8.180	EPSD	COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P13591	NCAM1	P28482	MAPK1	S613	G619R	619	Missense	distal	6	no	8.222	8.192	EPSD	COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P13591	NCAM1	P28482	MAPK1	S613	A614V	614	Missense	proximal	1	no	8.222	6.312	EPSD	COSMIC	8.102	Loss
CMGC_MAPK_ERK1_MAPK1_ST	P13591	NCAM1	P28482	MAPK1	S613	A614T	614	Missense	proximal	1	no	8.222	7.354	EPSD	COSMIC	8.102	Loss
CMGC_MAPK_ERK1_MAPK1_ST	P13591	NCAM1	P28482	MAPK1	S613	G619E	619	Missense	distal	6	no	8.222	8.333	EPSD	COSMIC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P13591	NCAM1	P28482	MAPK1	T798	R792Q	792	Missense	distal	-6	no	12.153	12.130	EPSD	COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P13591	NCAM1	P28482	MAPK1	T798	H801N	801	Missense	distal	3	no	12.153	12.056	EPSD	COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P13591	NCAM1	P28482	MAPK1	T813	E819K	819	Missense	distal	6	no	13.311	13.334	EPSD	COSMIC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P13591	NCAM1	P28482	MAPK1	T813	E811K	811	Missense	proximal	-2	no	13.311	13.271	EPSD	COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P15923	TCF3	P28482	MAPK1	S110	G112R	112	Missense	proximal	2	no	9.107	9.202	EPSD	COSMIC;GDSC;CCLE	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P15923	TCF3	P28482	MAPK1	S110	V117M	117	Missense	distal	7	no	9.107	9.184	EPSD	COSMIC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P15923	TCF3	P28482	MAPK1	S110	E104K	104	Missense	distal	-6	no	9.107	9.081	EPSD	COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P15923	TCF3	P28482	MAPK1	S110	R105W	105	Missense	distal	-5	no	9.107	9.383	EPSD	COSMIC;GDSC;CCLE	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P15923	TCF3	P28482	MAPK1	S110	G103S	103	Missense	distal	-7	no	9.107	9.121	EPSD	COSMIC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P15923	TCF3	P28482	MAPK1	S134	E129K	129	Missense	distal	-5	no	14.698	14.675	EPSD	COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P15923	TCF3	P28482	MAPK1	S134	S139F	139	Missense	distal	5	no	14.698	14.501	EPSD	COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P15923	TCF3	P28482	MAPK1	S134	S141L	141	Missense	distal	7	no	14.698	14.986	EPSD	COSMIC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P15923	TCF3	P28482	MAPK1	S134	P135L	135	Missense	proximal	1	no	14.698	5.888	EPSD	COSMIC	8.102	Loss
CMGC_MAPK_ERK1_MAPK1_ST	P15923	TCF3	P28482	MAPK1	S139	S139F	139	Missense	central	0	yes	18.181	0.000	EPSD	COSMIC	8.102	Loss
CMGC_MAPK_ERK1_MAPK1_ST	P15923	TCF3	P28482	MAPK1	S139	S141L	141	Missense	proximal	2	no	18.181	18.061	EPSD	COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P15923	TCF3	P28482	MAPK1	S139	P135L	135	Missense	distal	-4	no	18.181	17.877	EPSD	COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P15923	TCF3	P28482	MAPK1	T205	A203T	203	Missense	proximal	-2	no	13.439	13.887	EPSD	COSMIC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P15923	TCF3	P28482	MAPK1	T205	A212T	212	Missense	distal	7	no	13.439	13.410	EPSD	COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P15923	TCF3	P28482	MAPK1	S208	A203T	203	Missense	distal	-5	no	9.363	9.341	EPSD	COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P15923	TCF3	P28482	MAPK1	S208	A212T	212	Missense	distal	4	no	9.363	9.344	EPSD	COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P15923	TCF3	P28482	MAPK1	S229	P230S	230	Missense	proximal	1	no	14.399	5.004	EPSD	COSMIC	8.102	Loss
CMGC_MAPK_ERK1_MAPK1_ST	P15923	TCF3	P28482	MAPK1	S245	P248S	248	Missense	distal	3	no	13.753	13.823	EPSD	COSMIC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P15923	TCF3	P28482	MAPK1	S245	G252S	252	Missense	distal	7	no	13.753	13.685	EPSD	COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P15923	TCF3	P28482	MAPK1	S245	S244L	244	Missense	proximal	-1	no	13.753	13.737	EPSD	COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P15923	TCF3	P28482	MAPK1	S306	G313V	313	Missense	distal	7	no	7.965	8.179	EPSD	COSMIC	8.102	Gain
CMGC_MAPK_ERK1_MAPK1_ST	P15923	TCF3	P28482	MAPK1	T308	P309L	309	Missense	proximal	1	no	13.017	4.207	EPSD	COSMIC;CCLE	8.102	Loss
CMGC_MAPK_ERK1_MAPK1_ST	P15923	TCF3	P28482	MAPK1	T308	G313V	313	Missense	distal	5	no	13.017	12.893	EPSD	COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P15923	TCF3	P28482	MAPK1	T308	G313R	313	Missense	distal	5	no	13.017	13.068	EPSD	COSMIC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P15923	TCF3	P28482	MAPK1	S341	S346N	346	Missense	distal	5	no	15.206	15.134	EPSD	COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P15923	TCF3	P28482	MAPK1	S352	S346N	346	Missense	distal	-6	no	12.993	12.997	PhosphoSitePlus;EPSD	COSMIC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P15923	TCF3	P28482	MAPK1	S352	P353L	353	Missense	proximal	1	no	12.993	4.184	PhosphoSitePlus;EPSD	COSMIC;CCLE	8.102	Loss
CMGC_MAPK_ERK1_MAPK1_ST	P15923	TCF3	P28482	MAPK1	T355	P353L	353	Missense	proximal	-2	no	17.332	15.415	EPSD;PhosphoSitePlus	COSMIC;CCLE	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P15923	TCF3	P28482	MAPK1	T355	G362D	362	Missense	distal	7	no	17.332	17.260	EPSD;PhosphoSitePlus	COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P15923	TCF3	P28482	MAPK1	S359	P353L	353	Missense	distal	-6	no	16.175	16.083	EPSD;PhosphoSitePlus	COSMIC;CCLE	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P15923	TCF3	P28482	MAPK1	S359	T366M	366	Missense	distal	7	no	16.175	16.382	EPSD;PhosphoSitePlus	COSMIC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P15923	TCF3	P28482	MAPK1	S359	G362D	362	Missense	distal	3	no	16.175	16.178	EPSD;PhosphoSitePlus	COSMIC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P15923	TCF3	P28482	MAPK1	S379	G373R	373	Missense	distal	-6	no	13.460	13.512	EPSD	COSMIC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P15923	TCF3	P28482	MAPK1	S379	G385S	385	Missense	distal	6	no	13.460	13.538	EPSD	COSMIC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P15923	TCF3	P28482	MAPK1	S379	G385R	385	Missense	distal	6	no	13.460	13.431	EPSD	COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P15923	TCF3	P28482	MAPK1	S529	A523V	523	Missense	distal	-6	no	15.759	15.711	EPSD	COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P15923	TCF3	P28482	MAPK1	S529	P530R	530	Missense	proximal	1	no	15.759	6.104	EPSD	COSMIC;GDSC;CCLE	8.102	Loss
CMGC_MAPK_ERK1_MAPK1_ST	P15923	TCF3	P28482	MAPK1	S529	R527Q	527	Missense	proximal	-2	no	15.759	14.583	EPSD	COSMIC;CCLE	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P15923	TCF3	P28482	MAPK1	S529	E532K	532	Missense	distal	3	no	15.759	15.765	EPSD	COSMIC;GDSC;CCLE	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P15923	TCF3	P28482	MAPK1	S529	R525G	525	Missense	distal	-4	no	15.759	15.498	EPSD	COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P15923	TCF3	P28482	MAPK1	S529	E534K	534	Missense	distal	5	no	15.759	15.699	EPSD	COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q96RK0	CIC	P28482	MAPK1	S12	R6G	6	Missense	distal	-6	no	8.480	8.429	EPSD	COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q96RK0	CIC	P28482	MAPK1	S12	P10S	10	Missense	proximal	-2	no	8.480	5.646	EPSD	COSMIC	8.102	Loss
CMGC_MAPK_ERK1_MAPK1_ST	Q96RK0	CIC	P28482	MAPK1	S13	R6G	6	Missense	distal	-7	no	8.942	8.929	EPSD	COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q96RK0	CIC	P28482	MAPK1	S13	P10S	10	Missense	distal	-3	no	8.942	8.766	EPSD	COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q96RK0	CIC	P28482	MAPK1	S13	G20D	20	Missense	distal	7	no	8.942	8.870	EPSD	COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q96RK0	CIC	P28482	MAPK1	S105	G107E	107	Missense	proximal	2	no	16.034	15.948	EPSD	COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q96RK0	CIC	P28482	MAPK1	S105	G109R	109	Missense	distal	4	no	16.034	16.060	EPSD	COSMIC;GDSC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q96RK0	CIC	P28482	MAPK1	S105	P106S	106	Missense	proximal	1	no	16.034	6.639	EPSD	COSMIC	8.102	Loss
CMGC_MAPK_ERK1_MAPK1_ST	Q96RK0	CIC	P28482	MAPK1	S157	A151V	151	Missense	distal	-6	no	13.929	13.882	EPSD	COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q96RK0	CIC	P28482	MAPK1	S157	I155V	155	Missense	proximal	-2	no	13.929	13.951	EPSD	COSMIC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q96RK0	CIC	P28482	MAPK1	S157	S157C	157	Missense	central	0	yes	13.929	0.000	EPSD	COSMIC	8.102	Loss
CMGC_MAPK_ERK1_MAPK1_ST	Q96RK0	CIC	P28482	MAPK1	S157	M156I	156	Missense	proximal	-1	no	13.929	13.913	EPSD	COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q96RK0	CIC	P28482	MAPK1	S157	I160N	160	Missense	distal	3	no	13.929	13.793	EPSD	COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q96RK0	CIC	P28482	MAPK1	S157	L162F	162	Missense	distal	5	no	13.929	13.963	EPSD	COSMIC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q96RK0	CIC	P28482	MAPK1	S157	P158L	158	Missense	proximal	1	no	13.929	5.119	EPSD	COSMIC	8.102	Loss
CMGC_MAPK_ERK1_MAPK1_ST	Q96RK0	CIC	P28482	MAPK1	S191	R195Q	195	Missense	distal	4	no	14.663	14.588	EPSD	COSMIC;GDSC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q96RK0	CIC	P28482	MAPK1	S191	R190C	190	Missense	proximal	-1	no	14.663	14.560	EPSD	COSMIC;CCLE	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q96RK0	CIC	P28482	MAPK1	S285	L286Q	286	Missense	proximal	1	no	8.461	8.777	EPSD	COSMIC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q96RK0	CIC	P28482	MAPK1	S285	H292R	292	Missense	distal	7	no	8.461	8.242	EPSD	COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q96RK0	CIC	P28482	MAPK1	S285	G287W	287	Missense	proximal	2	no	8.461	8.188	EPSD	COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q96RK0	CIC	P28482	MAPK1	S349	A354S	354	Missense	distal	5	no	8.071	8.230	EPSD	COSMIC	8.102	Gain
CMGC_MAPK_ERK1_MAPK1_ST	Q96RK0	CIC	P28482	MAPK1	T393	G399V	399	Missense	distal	6	no	8.549	8.412	EPSD	COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q96RK0	CIC	P28482	MAPK1	T393	P391S	391	Missense	proximal	-2	no	8.549	5.715	EPSD	COSMIC	8.102	Loss
CMGC_MAPK_ERK1_MAPK1_ST	Q96RK0	CIC	P28482	MAPK1	T393	Y395D	395	Missense	proximal	2	no	8.549	8.729	EPSD	COSMIC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q96RK0	CIC	P28482	MAPK1	T393	A397V	397	Missense	distal	4	no	8.549	8.543	EPSD	COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q96RK0	CIC	P28482	MAPK1	S496	S501Y	501	Missense	distal	5	no	16.403	16.115	EPSD	COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q96RK0	CIC	P28482	MAPK1	S496	P497S	497	Missense	proximal	1	no	16.403	7.008	EPSD	COSMIC	8.102	Loss
CMGC_MAPK_ERK1_MAPK1_ST	Q96RK0	CIC	P28482	MAPK1	S496	R500H	500	Missense	distal	4	no	16.403	16.261	EPSD	COSMIC;GDSC;CCLE	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q96RK0	CIC	P28482	MAPK1	S502	P509L	509	Missense	distal	7	no	7.916	8.215	EPSD	COSMIC	8.102	Gain
CMGC_MAPK_ERK1_MAPK1_ST	Q96RK0	CIC	P28482	MAPK1	S538	S535F	535	Missense	distal	-3	no	12.538	12.305	EPSD	COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q96RK0	CIC	P28482	MAPK1	S538	A536V	536	Missense	proximal	-2	no	12.538	13.812	EPSD	COSMIC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q96RK0	CIC	P28482	MAPK1	S538	A531T	531	Missense	distal	-7	no	12.538	12.523	EPSD	COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q96RK0	CIC	P28482	MAPK1	S538	P532L	532	Missense	distal	-6	no	12.538	12.446	EPSD	COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q96RK0	CIC	P28482	MAPK1	S538	S538L	538	Missense	central	0	yes	12.538	0.000	EPSD	COSMIC	8.102	Loss
CMGC_MAPK_ERK1_MAPK1_ST	Q96RK0	CIC	P28482	MAPK1	S538	A544P	544	Missense	distal	6	no	12.538	12.834	EPSD	COSMIC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q96RK0	CIC	P28482	MAPK1	S543	A544P	544	Missense	proximal	1	no	7.171	14.802	EPSD	COSMIC	8.102	Gain
CMGC_MAPK_ERK1_MAPK1_ST	Q96RK0	CIC	P28482	MAPK1	T583	A578V	578	Missense	distal	-5	no	16.950	16.921	EPSD	COSMIC;GDSC;CCLE	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q96RK0	CIC	P28482	MAPK1	S605	R600C	600	Missense	distal	-5	no	7.922	8.152	EPSD	COSMIC;CCLE	8.102	Gain
CMGC_MAPK_ERK1_MAPK1_ST	Q96RK0	CIC	P28482	MAPK1	S649	A656V	656	Missense	distal	7	no	8.087	8.189	EPSD	COSMIC	8.102	Gain
CMGC_MAPK_ERK1_MAPK1_ST	Q96RK0	CIC	P28482	MAPK1	S700	A699V	699	Missense	proximal	-1	no	12.565	12.576	EPSD	COSMIC;GDSC;CCLE	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q96RK0	CIC	P28482	MAPK1	S700	T693A	693	Missense	distal	-7	no	12.565	12.579	EPSD	COSMIC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q96RK0	CIC	P28482	MAPK1	S700	P701S	701	Missense	proximal	1	no	12.565	3.170	EPSD	COSMIC	8.102	Loss
CMGC_MAPK_ERK1_MAPK1_ST	Q96RK0	CIC	P28482	MAPK1	S700	A697T	697	Missense	distal	-3	no	12.565	12.723	EPSD	COSMIC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q96RK0	CIC	P28482	MAPK1	S700	R696W	696	Missense	distal	-4	no	12.565	11.622	EPSD	COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q96RK0	CIC	P28482	MAPK1	S700	A699T	699	Missense	proximal	-1	no	12.565	12.560	EPSD	COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q96RK0	CIC	P28482	MAPK1	S700	A705T	705	Missense	distal	5	no	12.565	12.651	EPSD	COSMIC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q96RK0	CIC	P28482	MAPK1	T704	M711V	711	Missense	distal	7	no	8.279	8.202	EPSD	COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q96RK0	CIC	P28482	MAPK1	T704	A699V	699	Missense	distal	-5	no	8.279	8.250	EPSD	COSMIC;GDSC;CCLE	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q96RK0	CIC	P28482	MAPK1	T704	P701S	701	Missense	distal	-3	no	8.279	8.102	EPSD	COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q96RK0	CIC	P28482	MAPK1	T704	A697T	697	Missense	distal	-7	no	8.279	8.264	EPSD	COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q96RK0	CIC	P28482	MAPK1	T704	A699T	699	Missense	distal	-5	no	8.279	8.256	EPSD	COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q96RK0	CIC	P28482	MAPK1	T704	R708K	708	Missense	distal	4	no	8.279	8.289	EPSD	COSMIC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q96RK0	CIC	P28482	MAPK1	T704	A705T	705	Missense	proximal	1	no	8.279	7.410	EPSD	COSMIC	8.102	Loss
CMGC_MAPK_ERK1_MAPK1_ST	Q96RK0	CIC	P28482	MAPK1	S721	G720V	720	Missense	proximal	-1	no	15.004	15.033	EPSD	COSMIC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q96RK0	CIC	P28482	MAPK1	S721	R716W	716	Missense	distal	-5	no	15.004	15.280	EPSD	COSMIC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q96RK0	CIC	P28482	MAPK1	S721	S726R	726	Missense	distal	5	no	15.004	15.036	EPSD	COSMIC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q96RK0	CIC	P28482	MAPK1	S721	S721F	721	Missense	central	0	yes	15.004	0.000	EPSD	COSMIC	8.102	Loss
CMGC_MAPK_ERK1_MAPK1_ST	Q96RK0	CIC	P28482	MAPK1	S721	S721C	721	Missense	central	0	yes	15.004	0.000	EPSD	COSMIC	8.102	Loss
CMGC_MAPK_ERK1_MAPK1_ST	Q96RK0	CIC	P28482	MAPK1	S739	P742S	742	Missense	distal	3	no	12.857	12.926	EPSD	COSMIC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q96RK0	CIC	P28482	MAPK1	S739	K732Q	732	Missense	distal	-7	no	12.857	12.861	EPSD	COSMIC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q96RK0	CIC	P28482	MAPK1	S894	A900V	900	Missense	distal	6	no	8.842	8.924	EPSD	COSMIC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q96RK0	CIC	P28482	MAPK1	S894	P896L	896	Missense	proximal	2	no	8.842	8.695	EPSD	COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q96RK0	CIC	P28482	MAPK1	S894	P893S	893	Missense	proximal	-1	no	8.842	8.799	EPSD	COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q96RK0	CIC	P28482	MAPK1	S894	P897R	897	Missense	distal	3	no	8.842	8.888	EPSD	COSMIC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q96RK0	CIC	P28482	MAPK1	S894	S894C	894	Missense	central	0	yes	8.842	0.000	EPSD	COSMIC	8.102	Loss
CMGC_MAPK_ERK1_MAPK1_ST	Q96RK0	CIC	P28482	MAPK1	S904	A900V	900	Missense	distal	-4	no	15.460	15.400	EPSD	COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q96RK0	CIC	P28482	MAPK1	S904	P897R	897	Missense	distal	-7	no	15.460	15.455	EPSD	COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q96RK0	CIC	P28482	MAPK1	S904	P911S	911	Missense	distal	7	no	15.460	15.471	EPSD	COSMIC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q96RK0	CIC	P28482	MAPK1	S904	P911L	911	Missense	distal	7	no	15.460	15.759	EPSD	COSMIC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q96RK0	CIC	P28482	MAPK1	S914	P911S	911	Missense	distal	-3	no	8.312	8.136	EPSD	COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q96RK0	CIC	P28482	MAPK1	S914	P911L	911	Missense	distal	-3	no	8.312	7.928	EPSD	COSMIC	8.102	Loss
CMGC_MAPK_ERK1_MAPK1_ST	Q96RK0	CIC	P28482	MAPK1	S914	S914A	914	Missense	central	0	yes	8.312	0.000	EPSD	COSMIC	8.102	Loss
CMGC_MAPK_ERK1_MAPK1_ST	Q96RK0	CIC	P28482	MAPK1	S946	P943S	943	Missense	distal	-3	no	15.138	14.961	EPSD	COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q96RK0	CIC	P28482	MAPK1	S946	F949L	949	Missense	distal	3	no	15.138	15.096	EPSD	COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q96RK0	CIC	P28482	MAPK1	S946	S946I	946	Missense	central	0	yes	15.138	0.000	EPSD	COSMIC	8.102	Loss
CMGC_MAPK_ERK1_MAPK1_ST	Q96RK0	CIC	P28482	MAPK1	S946	V945M	945	Missense	proximal	-1	no	15.138	15.114	EPSD	COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q96RK0	CIC	P28482	MAPK1	S982	P987S	987	Missense	distal	5	no	16.761	16.779	EPSD	COSMIC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q96RK0	CIC	P28482	MAPK1	S982	P983S	983	Missense	proximal	1	no	16.761	7.366	EPSD	COSMIC	8.102	Loss
CMGC_MAPK_ERK1_MAPK1_ST	Q96RK0	CIC	P28482	MAPK1	S982	L986V	986	Missense	distal	4	no	16.761	16.772	EPSD	COSMIC;GDSC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q96RK0	CIC	P28482	MAPK1	S982	P980L	980	Missense	proximal	-2	no	16.761	14.844	EPSD	COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q96RK0	CIC	P28482	MAPK1	T1145	P1146L	1146	Missense	proximal	1	no	13.675	4.865	EPSD	COSMIC;GDSC	8.102	Loss
CMGC_MAPK_ERK1_MAPK1_ST	Q96RK0	CIC	P28482	MAPK1	T1145	A1147V	1147	Missense	proximal	2	no	13.675	13.751	EPSD	COSMIC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q96RK0	CIC	P28482	MAPK1	T1145	P1141S	1141	Missense	distal	-4	no	13.675	13.591	EPSD	COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q96RK0	CIC	P28482	MAPK1	T1145	P1148L	1148	Missense	distal	3	no	13.675	13.764	EPSD	COSMIC;GDSC;CCLE	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q96RK0	CIC	P28482	MAPK1	T1145	P1138L	1138	Missense	distal	-7	no	13.675	13.663	EPSD	COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q96RK0	CIC	P28482	MAPK1	T1145	P1141T	1141	Missense	distal	-4	no	13.675	13.361	EPSD	COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q96RK0	CIC	P28482	MAPK1	T1145	A1142T	1142	Missense	distal	-3	no	13.675	13.832	EPSD	COSMIC;GDSC;CCLE	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q96RK0	CIC	P28482	MAPK1	S1150	P1146L	1146	Missense	distal	-4	no	17.040	16.736	EPSD	COSMIC;GDSC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q96RK0	CIC	P28482	MAPK1	S1150	A1147V	1147	Missense	distal	-3	no	17.040	17.100	EPSD	COSMIC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q96RK0	CIC	P28482	MAPK1	S1150	P1148L	1148	Missense	proximal	-2	no	17.040	15.123	EPSD	COSMIC;GDSC;CCLE	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q96RK0	CIC	P28482	MAPK1	S1150	A1155T	1155	Missense	distal	5	no	17.040	17.126	EPSD	COSMIC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q96RK0	CIC	P28482	MAPK1	S1173	P1177H	1177	Missense	distal	4	no	14.359	14.184	EPSD	COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q96RK0	CIC	P28482	MAPK1	S1173	P1174L	1174	Missense	proximal	1	no	14.359	5.550	EPSD	COSMIC	8.102	Loss
CMGC_MAPK_ERK1_MAPK1_ST	Q96RK0	CIC	P28482	MAPK1	S1191	P1188A	1188	Missense	distal	-3	no	8.179	7.812	EPSD	COSMIC	8.102	Loss
CMGC_MAPK_ERK1_MAPK1_ST	Q96RK0	CIC	P28482	MAPK1	S1191	G1190R	1190	Missense	proximal	-1	no	8.179	8.214	EPSD	COSMIC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q96RK0	CIC	P28482	MAPK1	S1191	G1190V	1190	Missense	proximal	-1	no	8.179	8.207	EPSD	COSMIC;GDSC;CCLE	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q96RK0	CIC	P28482	MAPK1	S1191	P1188S	1188	Missense	distal	-3	no	8.179	8.002	EPSD	COSMIC	8.102	Loss
CMGC_MAPK_ERK1_MAPK1_ST	Q96RK0	CIC	P28482	MAPK1	T1228	P1230S	1230	Missense	proximal	2	no	14.763	14.735	EPSD	COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q96RK0	CIC	P28482	MAPK1	T1228	P1234L	1234	Missense	distal	6	no	14.763	14.356	EPSD	COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q96RK0	CIC	P28482	MAPK1	T1228	P1229A	1229	Missense	proximal	1	no	14.763	7.133	EPSD	COSMIC	8.102	Loss
CMGC_MAPK_ERK1_MAPK1_ST	Q96RK0	CIC	P28482	MAPK1	T1228	T1228I	1228	Missense	central	0	yes	14.763	0.000	EPSD	COSMIC	8.102	Loss
CMGC_MAPK_ERK1_MAPK1_ST	Q96RK0	CIC	P28482	MAPK1	T1228	E1222Q	1222	Missense	distal	-6	no	14.763	14.737	EPSD	COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q96RK0	CIC	P28482	MAPK1	T1228	P1227A	1227	Missense	proximal	-1	no	14.763	14.726	EPSD	COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q96RK0	CIC	P28482	MAPK1	T1228	E1222G	1222	Missense	distal	-6	no	14.763	14.709	EPSD	COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q96RK0	CIC	P28482	MAPK1	T1228	P1232L	1232	Missense	distal	4	no	14.763	14.642	EPSD	COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q96RK0	CIC	P28482	MAPK1	T1238	P1236S	1236	Missense	proximal	-2	no	8.879	6.045	EPSD	COSMIC	8.102	Loss
CMGC_MAPK_ERK1_MAPK1_ST	Q96RK0	CIC	P28482	MAPK1	T1238	P1234L	1234	Missense	distal	-4	no	8.879	8.575	EPSD	COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q96RK0	CIC	P28482	MAPK1	T1238	W1239R	1239	Missense	proximal	1	no	8.879	6.601	EPSD	COSMIC	8.102	Loss
CMGC_MAPK_ERK1_MAPK1_ST	Q96RK0	CIC	P28482	MAPK1	T1238	T1242R	1242	Missense	distal	4	no	8.879	8.969	EPSD	COSMIC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q96RK0	CIC	P28482	MAPK1	T1238	P1234S	1234	Missense	distal	-4	no	8.879	8.795	EPSD	COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q96RK0	CIC	P28482	MAPK1	T1238	T1240R	1240	Missense	proximal	2	no	8.879	9.043	EPSD	COSMIC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q96RK0	CIC	P28482	MAPK1	T1238	P1232L	1232	Missense	distal	-6	no	8.879	8.787	EPSD	COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q96RK0	CIC	P28482	MAPK1	T1240	P1236S	1236	Missense	distal	-4	no	13.602	13.518	EPSD	COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q96RK0	CIC	P28482	MAPK1	T1240	P1234L	1234	Missense	distal	-6	no	13.602	13.510	EPSD	COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q96RK0	CIC	P28482	MAPK1	T1240	W1239R	1239	Missense	proximal	-1	no	13.602	13.703	EPSD	COSMIC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q96RK0	CIC	P28482	MAPK1	T1240	T1242R	1242	Missense	proximal	2	no	13.602	13.766	EPSD	COSMIC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q96RK0	CIC	P28482	MAPK1	T1240	P1234S	1234	Missense	distal	-6	no	13.602	13.576	EPSD	COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q96RK0	CIC	P28482	MAPK1	T1240	T1240R	1240	Missense	central	0	yes	13.602	0.000	EPSD	COSMIC	8.102	Loss
CMGC_MAPK_ERK1_MAPK1_ST	Q96RK0	CIC	P28482	MAPK1	S1246	P1248L	1248	Missense	proximal	2	no	16.144	15.996	EPSD	COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q96RK0	CIC	P28482	MAPK1	S1246	W1239R	1239	Missense	distal	-7	no	16.144	16.195	EPSD	COSMIC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q96RK0	CIC	P28482	MAPK1	S1246	P1248S	1248	Missense	proximal	2	no	16.144	16.116	EPSD	COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q96RK0	CIC	P28482	MAPK1	S1246	T1242R	1242	Missense	distal	-4	no	16.144	16.368	EPSD	COSMIC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q96RK0	CIC	P28482	MAPK1	S1246	T1240R	1240	Missense	distal	-6	no	16.144	16.202	EPSD	COSMIC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q96RK0	CIC	P28482	MAPK1	T1291	P1292S	1292	Missense	proximal	1	no	17.146	7.751	EPSD	COSMIC	8.102	Loss
CMGC_MAPK_ERK1_MAPK1_ST	Q96RK0	CIC	P28482	MAPK1	T1291	P1292L	1292	Missense	proximal	1	no	17.146	8.336	EPSD	COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q96RK0	CIC	P28482	MAPK1	T1291	P1295S	1295	Missense	distal	4	no	17.146	17.135	EPSD	COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q96RK0	CIC	P28482	MAPK1	T1291	R1286C	1286	Missense	distal	-5	no	17.146	17.376	EPSD	COSMIC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q96RK0	CIC	P28482	MAPK1	T1291	S1294L	1294	Missense	distal	3	no	17.146	17.166	EPSD	COSMIC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q96RK0	CIC	P28482	MAPK1	T1291	P1292T	1292	Missense	proximal	1	no	17.146	8.647	EPSD	COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q96RK0	CIC	P28482	MAPK1	T1291	P1292H	1292	Missense	proximal	1	no	17.146	9.322	EPSD	COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q96RK0	CIC	P28482	MAPK1	T1291	G1287R	1287	Missense	distal	-4	no	17.146	17.407	EPSD	COSMIC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q96RK0	CIC	P28482	MAPK1	T1291	P1293S	1293	Missense	proximal	2	no	17.146	17.118	EPSD	COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q96RK0	CIC	P28482	MAPK1	T1291	P1290L	1290	Missense	proximal	-1	no	17.146	17.086	EPSD	COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q96RK0	CIC	P28482	MAPK1	T1291	P1290S	1290	Missense	proximal	-1	no	17.146	17.103	EPSD	COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q96RK0	CIC	P28482	MAPK1	S1294	P1292S	1292	Missense	proximal	-2	no	18.874	16.040	EPSD	COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q96RK0	CIC	P28482	MAPK1	S1294	P1292L	1292	Missense	proximal	-2	no	18.874	16.957	EPSD	COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q96RK0	CIC	P28482	MAPK1	S1294	P1295S	1295	Missense	proximal	1	no	18.874	9.479	EPSD	COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q96RK0	CIC	P28482	MAPK1	S1294	S1294L	1294	Missense	central	0	yes	18.874	0.000	EPSD	COSMIC	8.102	Loss
CMGC_MAPK_ERK1_MAPK1_ST	Q96RK0	CIC	P28482	MAPK1	S1294	P1292T	1292	Missense	proximal	-2	no	18.874	16.175	EPSD	COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q96RK0	CIC	P28482	MAPK1	S1294	P1292H	1292	Missense	proximal	-2	no	18.874	16.119	EPSD	COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q96RK0	CIC	P28482	MAPK1	S1294	G1287R	1287	Missense	distal	-7	no	18.874	18.887	EPSD	COSMIC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q96RK0	CIC	P28482	MAPK1	S1294	P1293S	1293	Missense	proximal	-1	no	18.874	18.831	EPSD	COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q96RK0	CIC	P28482	MAPK1	S1294	P1290L	1290	Missense	distal	-4	no	18.874	18.570	EPSD	COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q96RK0	CIC	P28482	MAPK1	S1294	P1290S	1290	Missense	distal	-4	no	18.874	18.790	EPSD	COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q96RK0	CIC	P28482	MAPK1	T1318	R1313W	1313	Missense	distal	-5	no	13.559	13.835	EPSD	COSMIC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q96RK0	CIC	P28482	MAPK1	T1318	P1319L	1319	Missense	proximal	1	no	13.559	4.749	EPSD	COSMIC	8.102	Loss
CMGC_MAPK_ERK1_MAPK1_ST	Q96RK0	CIC	P28482	MAPK1	T1318	G1316R	1316	Missense	proximal	-2	no	13.559	14.934	EPSD	COSMIC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q96RK0	CIC	P28482	MAPK1	T1318	G1316E	1316	Missense	proximal	-2	no	13.559	14.373	EPSD	COSMIC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q96RK0	CIC	P28482	MAPK1	S1373	E1368Q	1368	Missense	distal	-5	no	13.043	13.143	EPSD	COSMIC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q96RK0	CIC	P28482	MAPK1	S1373	T1375I	1375	Missense	proximal	2	no	13.043	12.923	EPSD	COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q96RK0	CIC	P28482	MAPK1	S1373	R1366W	1366	Missense	distal	-7	no	13.043	12.992	EPSD	COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q96RK0	CIC	P28482	MAPK1	S1373	S1378P	1378	Missense	distal	5	no	13.043	13.025	EPSD	COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q96RK0	CIC	P28482	MAPK1	S1382	R1384Q	1384	Missense	proximal	2	no	14.115	13.823	EPSD	COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q96RK0	CIC	P28482	MAPK1	S1382	S1382A	1382	Missense	central	0	yes	14.115	0.000	EPSD	COSMIC	8.102	Loss
CMGC_MAPK_ERK1_MAPK1_ST	Q96RK0	CIC	P28482	MAPK1	S1382	S1382L	1382	Missense	central	0	yes	14.115	0.000	EPSD	COSMIC	8.102	Loss
CMGC_MAPK_ERK1_MAPK1_ST	Q96RK0	CIC	P28482	MAPK1	S1382	T1375I	1375	Missense	distal	-7	no	14.115	14.100	EPSD	COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q96RK0	CIC	P28482	MAPK1	S1382	S1378P	1378	Missense	distal	-4	no	14.115	14.198	EPSD	COSMIC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q96RK0	CIC	P28482	MAPK1	S1409	R1412H	1412	Missense	distal	3	no	17.236	17.279	PhosphoSitePlus;EPSD	COSMIC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q96RK0	CIC	P28482	MAPK1	S1409	T1408I	1408	Missense	proximal	-1	no	17.236	17.212	PhosphoSitePlus;EPSD	COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q96RK0	CIC	P28482	MAPK1	S1409	R1416H	1416	Missense	distal	7	no	17.236	17.455	PhosphoSitePlus;EPSD	COSMIC;CCLE	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q96RK0	CIC	P28482	MAPK1	S1409	R1415L	1415	Missense	distal	6	no	17.236	16.936	PhosphoSitePlus;EPSD	COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q96RK0	CIC	P28482	MAPK1	T1426	C1432Y	1432	Missense	distal	6	no	14.873	15.122	EPSD	COSMIC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q96RK0	CIC	P28482	MAPK1	T1426	S1421G	1421	Missense	distal	-5	no	14.873	14.867	EPSD	COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q96RK0	CIC	P28482	MAPK1	T1426	P1427L	1427	Missense	proximal	1	no	14.873	6.064	EPSD	COSMIC	8.102	Loss
CMGC_MAPK_ERK1_MAPK1_ST	Q96RK0	CIC	P28482	MAPK1	T1426	P1424S	1424	Missense	proximal	-2	no	14.873	12.039	EPSD	COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q96RK0	CIC	P28482	MAPK1	T1426	S1419G	1419	Missense	distal	-7	no	14.873	14.860	EPSD	COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q96RK0	CIC	P28482	MAPK1	T1426	S1422W	1422	Missense	distal	-4	no	14.873	13.925	EPSD	COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q96RK0	CIC	P28482	MAPK1	S1429	C1432Y	1432	Missense	distal	3	no	10.046	10.001	EPSD	COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q96RK0	CIC	P28482	MAPK1	S1429	G1434C	1434	Missense	distal	5	no	10.046	9.666	EPSD	COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q96RK0	CIC	P28482	MAPK1	S1429	G1434V	1434	Missense	distal	5	no	10.046	9.923	EPSD	COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q96RK0	CIC	P28482	MAPK1	S1429	P1427L	1427	Missense	proximal	-2	no	10.046	8.129	EPSD	COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q96RK0	CIC	P28482	MAPK1	S1429	P1424S	1424	Missense	distal	-5	no	10.046	10.121	EPSD	COSMIC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q96RK0	CIC	P28482	MAPK1	S1429	S1422W	1422	Missense	distal	-7	no	10.046	9.995	EPSD	COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q96RK0	CIC	P28482	MAPK1	S1461	S1462A	1462	Missense	proximal	1	no	7.085	8.849	EPSD	COSMIC	8.102	Gain
CMGC_MAPK_ERK1_MAPK1_ST	Q96RK0	CIC	P28482	MAPK1	S1595	P1599S	1599	Missense	distal	4	no	16.271	16.260	EPSD	COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q96RK0	CIC	P28482	MAPK1	S1595	E1589Q	1589	Missense	distal	-6	no	16.271	16.245	EPSD	COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q96RK0	CIC	P28482	MAPK1	S1595	S1595F	1595	Missense	central	0	yes	16.271	0.000	EPSD	COSMIC	8.102	Loss
CMGC_MAPK_ERK1_MAPK1_ST	Q96RK0	CIC	P28482	MAPK1	S1595	P1594L	1594	Missense	proximal	-1	no	16.271	16.211	EPSD	COSMIC;CCLE	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q96RK0	CIC	P28482	MAPK1	S1595	P1592H	1592	Missense	distal	-3	no	16.271	15.921	EPSD	COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q96RK0	CIC	P28482	MAPK1	S1595	P1592L	1592	Missense	distal	-3	no	16.271	15.887	EPSD	COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q96RK0	CIC	P28482	MAPK1	S1595	P1592A	1592	Missense	distal	-3	no	16.271	15.904	EPSD	COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q96RK0	CIC	P28482	MAPK1	S1595	P1597S	1597	Missense	proximal	2	no	16.271	16.243	EPSD	COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P14598	NCF1	P28482	MAPK1	T138	T138K	138	Missense	central	0	yes	10.329	0.000	EPSD	COSMIC	8.102	Loss
CMGC_MAPK_ERK1_MAPK1_ST	P14598	NCF1	P28482	MAPK1	T138	D144E	144	Missense	distal	6	no	10.329	10.408	EPSD	COSMIC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P14598	NCF1	P28482	MAPK1	S345	P349R	349	Missense	distal	4	no	16.341	16.308	PhosphoSitePlus	COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P14598	NCF1	P28482	MAPK1	S348	P349R	349	Missense	proximal	1	no	17.083	7.429	EPSD	COSMIC	8.102	Loss
CMGC_MAPK_ERK1_MAPK1_ST	Q92793	CREBBP	P28482	MAPK1	S19	F22L	22	Missense	distal	3	no	17.504	17.462	EPSD	COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q92793	CREBBP	P28482	MAPK1	S19	P12H	12	Missense	distal	-7	no	17.504	17.488	EPSD	COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q92793	CREBBP	P28482	MAPK1	S19	P20T	20	Missense	proximal	1	no	17.504	9.005	EPSD	COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q92793	CREBBP	P28482	MAPK1	S19	G21D	21	Missense	proximal	2	no	17.504	17.470	EPSD	COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q92793	CREBBP	P28482	MAPK1	S23	F22L	22	Missense	proximal	-1	no	9.036	9.066	EPSD	COSMIC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q92793	CREBBP	P28482	MAPK1	S23	P20T	20	Missense	distal	-3	no	9.036	8.827	EPSD	COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q92793	CREBBP	P28482	MAPK1	S23	G21D	21	Missense	proximal	-2	no	9.036	8.928	EPSD	COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q92793	CREBBP	P28482	MAPK1	S27	F22L	22	Missense	distal	-5	no	8.129	8.115	EPSD	COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q92793	CREBBP	P28482	MAPK1	S27	L33F	33	Missense	distal	6	no	8.129	8.094	EPSD	COSMIC	8.102	Loss
CMGC_MAPK_ERK1_MAPK1_ST	Q92793	CREBBP	P28482	MAPK1	S27	P20T	20	Missense	distal	-7	no	8.129	8.112	EPSD	COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q92793	CREBBP	P28482	MAPK1	S27	G21D	21	Missense	distal	-6	no	8.129	8.195	EPSD	COSMIC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q92793	CREBBP	P28482	MAPK1	S93	V89M	89	Missense	distal	-4	no	13.467	13.356	PhosphoSitePlus	COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q92793	CREBBP	P28482	MAPK1	S121	S121I	121	Missense	central	0	yes	12.427	0.000	EPSD	COSMIC	8.102	Loss
CMGC_MAPK_ERK1_MAPK1_ST	Q92793	CREBBP	P28482	MAPK1	S121	S128C	128	Missense	distal	7	no	12.427	13.086	EPSD	COSMIC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q92793	CREBBP	P28482	MAPK1	S121	S116G	116	Missense	distal	-5	no	12.427	12.420	EPSD	COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q92793	CREBBP	P28482	MAPK1	S274	P275L	275	Missense	proximal	1	no	12.117	3.308	EPSD	COSMIC	8.102	Loss
CMGC_MAPK_ERK1_MAPK1_ST	Q92793	CREBBP	P28482	MAPK1	S274	P275S	275	Missense	proximal	1	no	12.117	2.723	EPSD	COSMIC	8.102	Loss
CMGC_MAPK_ERK1_MAPK1_ST	Q92793	CREBBP	P28482	MAPK1	S274	Q278P	278	Missense	distal	4	no	12.117	12.226	EPSD	COSMIC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q92793	CREBBP	P28482	MAPK1	S274	S274N	274	Missense	central	0	yes	12.117	0.000	EPSD	COSMIC	8.102	Loss
CMGC_MAPK_ERK1_MAPK1_ST	Q92793	CREBBP	P28482	MAPK1	S274	G268R	268	Missense	distal	-6	no	12.117	12.169	EPSD	COSMIC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q92793	CREBBP	P28482	MAPK1	S274	P275Q	275	Missense	proximal	1	no	12.117	3.624	EPSD	COSMIC	8.102	Loss
CMGC_MAPK_ERK1_MAPK1_ST	Q92793	CREBBP	P28482	MAPK1	S281	P275L	275	Missense	distal	-6	no	8.264	8.172	EPSD	COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q92793	CREBBP	P28482	MAPK1	S281	P275S	275	Missense	distal	-6	no	8.264	8.238	EPSD	COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q92793	CREBBP	P28482	MAPK1	S281	Q278P	278	Missense	distal	-3	no	8.264	8.561	EPSD	COSMIC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q92793	CREBBP	P28482	MAPK1	S281	S274N	274	Missense	distal	-7	no	8.264	8.266	EPSD	COSMIC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q92793	CREBBP	P28482	MAPK1	S281	P275Q	275	Missense	distal	-6	no	8.264	8.249	EPSD	COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q92793	CREBBP	P28482	MAPK1	T309	N305D	305	Missense	distal	-4	no	8.161	8.190	EPSD	COSMIC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q92793	CREBBP	P28482	MAPK1	T309	S302N	302	Missense	distal	-7	no	8.161	8.164	EPSD	COSMIC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q92793	CREBBP	P28482	MAPK1	T309	P308S	308	Missense	proximal	-1	no	8.161	8.118	EPSD	COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q92793	CREBBP	P28482	MAPK1	T309	N305H	305	Missense	distal	-4	no	8.161	7.962	EPSD	COSMIC	8.102	Loss
CMGC_MAPK_ERK1_MAPK1_ST	Q92793	CREBBP	P28482	MAPK1	S745	R742P	742	Missense	distal	-3	no	16.277	16.297	EPSD	COSMIC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q92793	CREBBP	P28482	MAPK1	S745	M747V	747	Missense	proximal	2	no	16.277	16.414	EPSD	COSMIC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q92793	CREBBP	P28482	MAPK1	S745	V751A	751	Missense	distal	6	no	16.277	16.196	EPSD	COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q92793	CREBBP	P28482	MAPK1	S745	R742L	742	Missense	distal	-3	no	16.277	15.913	EPSD	COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q92793	CREBBP	P28482	MAPK1	T974	V978M	978	Missense	distal	4	no	13.267	13.178	EPSD	COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q92793	CREBBP	P28482	MAPK1	T974	P975S	975	Missense	proximal	1	no	13.267	3.872	EPSD	COSMIC	8.102	Loss
CMGC_MAPK_ERK1_MAPK1_ST	Q92793	CREBBP	P28482	MAPK1	T974	D969H	969	Missense	distal	-5	no	13.267	13.322	EPSD	COSMIC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q92793	CREBBP	P28482	MAPK1	T974	A981T	981	Missense	distal	7	no	13.267	13.238	EPSD	COSMIC;GDSC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q92793	CREBBP	P28482	MAPK1	T974	S977L	977	Missense	distal	3	no	13.267	13.287	EPSD	COSMIC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q92793	CREBBP	P28482	MAPK1	T974	S967N	967	Missense	distal	-7	no	13.267	13.269	EPSD	COSMIC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q92793	CREBBP	P28482	MAPK1	T974	S977P	977	Missense	distal	3	no	13.267	13.198	EPSD	COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q92793	CREBBP	P28482	MAPK1	T974	N970I	970	Missense	distal	-4	no	13.267	12.639	EPSD	COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q92793	CREBBP	P28482	MAPK1	S976	S977P	977	Missense	proximal	1	no	4.440	13.835	EPSD	COSMIC	8.102	Gain
CMGC_MAPK_ERK1_MAPK1_ST	Q92793	CREBBP	P28482	MAPK1	S1019	E1016D	1016	Missense	distal	-3	no	9.150	9.201	EPSD	COSMIC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q92793	CREBBP	P28482	MAPK1	S1019	M1021I	1021	Missense	proximal	2	no	9.150	9.170	EPSD	COSMIC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q92793	CREBBP	P28482	MAPK1	S1019	G1015V	1015	Missense	distal	-4	no	9.150	9.146	EPSD	COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q92793	CREBBP	P28482	MAPK1	S1019	E1020V	1020	Missense	proximal	1	no	9.150	8.381	EPSD	COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q92793	CREBBP	P28482	MAPK1	S1019	E1020G	1020	Missense	proximal	1	no	9.150	7.856	EPSD	COSMIC	8.102	Loss
CMGC_MAPK_ERK1_MAPK1_ST	Q92793	CREBBP	P28482	MAPK1	S1019	E1020Q	1020	Missense	proximal	1	no	9.150	9.428	EPSD	COSMIC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q92793	CREBBP	P28482	MAPK1	S1019	K1014Q	1014	Missense	distal	-5	no	9.150	9.273	EPSD	COSMIC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q92793	CREBBP	P28482	MAPK1	S1076	A1071T	1071	Missense	distal	-5	no	15.986	15.964	EPSD	COSMIC;GDSC;CCLE	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q92793	CREBBP	P28482	MAPK1	S1076	S1072F	1072	Missense	distal	-4	no	15.986	15.725	EPSD	COSMIC;GDSC;CCLE	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q92793	CREBBP	P28482	MAPK1	S1076	G1069S	1069	Missense	distal	-7	no	15.986	16.000	EPSD	COSMIC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q92793	CREBBP	P28482	MAPK1	S1076	P1080R	1080	Missense	distal	4	no	15.986	15.953	EPSD	COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q92793	CREBBP	P28482	MAPK1	S1076	G1069R	1069	Missense	distal	-7	no	15.986	15.999	EPSD	COSMIC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q92793	CREBBP	P28482	MAPK1	S1076	R1081H	1081	Missense	distal	5	no	15.986	15.809	EPSD	COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q92793	CREBBP	P28482	MAPK1	S1076	G1069D	1069	Missense	distal	-7	no	15.986	16.001	EPSD	COSMIC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q92793	CREBBP	P28482	MAPK1	S1076	Q1073E	1073	Missense	distal	-3	no	15.986	16.103	EPSD	COSMIC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q92793	CREBBP	P28482	MAPK1	S1076	Q1079H	1079	Missense	distal	3	no	15.986	16.007	EPSD	COSMIC;GDSC;CCLE	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q92793	CREBBP	P28482	MAPK1	S1763	P1759T	1759	Missense	distal	-4	no	15.448	15.135	EPSD	COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q92793	CREBBP	P28482	MAPK1	S1763	Q1765L	1765	Missense	proximal	2	no	15.448	15.479	EPSD	COSMIC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q92793	CREBBP	P28482	MAPK1	S1763	Q1756R	1756	Missense	distal	-7	no	15.448	15.440	EPSD	COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q92793	CREBBP	P28482	MAPK1	S1763	Q1765R	1765	Missense	proximal	2	no	15.448	15.739	EPSD	COSMIC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q92793	CREBBP	P28482	MAPK1	S1884	P1885S	1885	Missense	proximal	1	no	14.906	5.511	EPSD	COSMIC	8.102	Loss
CMGC_MAPK_ERK1_MAPK1_ST	Q92793	CREBBP	P28482	MAPK1	S1884	Q1880L	1880	Missense	distal	-4	no	14.906	14.794	EPSD	COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q92793	CREBBP	P28482	MAPK1	S1884	Q1879E	1879	Missense	distal	-5	no	14.906	14.806	EPSD	COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q92793	CREBBP	P28482	MAPK1	S1884	Q1879K	1879	Missense	distal	-5	no	14.906	14.784	EPSD	COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q92793	CREBBP	P28482	MAPK1	S1884	P1889L	1889	Missense	distal	5	no	14.906	14.693	EPSD	COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q92793	CREBBP	P28482	MAPK1	S1887	P1885S	1885	Missense	proximal	-2	no	9.839	7.004	EPSD	COSMIC	8.102	Loss
CMGC_MAPK_ERK1_MAPK1_ST	Q92793	CREBBP	P28482	MAPK1	S1887	Q1880L	1880	Missense	distal	-7	no	9.839	9.824	EPSD	COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q92793	CREBBP	P28482	MAPK1	S1887	P1889L	1889	Missense	proximal	2	no	9.839	9.691	EPSD	COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q92793	CREBBP	P28482	MAPK1	S1887	T1894M	1894	Missense	distal	7	no	9.839	10.046	EPSD	COSMIC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q92793	CREBBP	P28482	MAPK1	T1892	P1885S	1885	Missense	distal	-7	no	16.093	16.089	EPSD	COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q92793	CREBBP	P28482	MAPK1	T1892	S1898I	1898	Missense	distal	6	no	16.093	15.426	EPSD	COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q92793	CREBBP	P28482	MAPK1	T1892	P1897H	1897	Missense	distal	5	no	16.093	15.966	EPSD	COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q92793	CREBBP	P28482	MAPK1	T1892	P1889L	1889	Missense	distal	-3	no	16.093	15.710	EPSD	COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q92793	CREBBP	P28482	MAPK1	T1892	T1894M	1894	Missense	proximal	2	no	16.093	15.953	EPSD	COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q92793	CREBBP	P28482	MAPK1	T1899	T1902M	1902	Missense	distal	3	no	17.247	17.270	EPSD	COSMIC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q92793	CREBBP	P28482	MAPK1	T1899	S1898I	1898	Missense	proximal	-1	no	17.247	17.224	EPSD	COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q92793	CREBBP	P28482	MAPK1	T1899	Q1904H	1904	Missense	distal	5	no	17.247	17.240	EPSD	COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q92793	CREBBP	P28482	MAPK1	T1899	P1897H	1897	Missense	proximal	-2	no	17.247	14.492	EPSD	COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q92793	CREBBP	P28482	MAPK1	T1899	P1905L	1905	Missense	distal	6	no	17.247	16.841	EPSD	COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q92793	CREBBP	P28482	MAPK1	T1899	T1894M	1894	Missense	distal	-5	no	17.247	17.297	EPSD	COSMIC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q92793	CREBBP	P28482	MAPK1	T1899	P1900H	1900	Missense	proximal	1	no	17.247	9.423	EPSD	COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q92793	CREBBP	P28482	MAPK1	S1912	S1912P	1912	Missense	central	0	yes	12.962	0.000	EPSD	COSMIC	8.102	Loss
CMGC_MAPK_ERK1_MAPK1_ST	Q92793	CREBBP	P28482	MAPK1	S1912	Q1908R	1908	Missense	distal	-4	no	12.962	13.066	EPSD	COSMIC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q92793	CREBBP	P28482	MAPK1	S1912	P1911L	1911	Missense	proximal	-1	no	12.962	12.902	EPSD	COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q92793	CREBBP	P28482	MAPK1	S1912	A1907V	1907	Missense	distal	-5	no	12.962	12.934	EPSD	COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q92793	CREBBP	P28482	MAPK1	S1912	S1912L	1912	Missense	central	0	yes	12.962	0.000	EPSD	COSMIC	8.102	Loss
CMGC_MAPK_ERK1_MAPK1_ST	Q92793	CREBBP	P28482	MAPK1	S1912	A1907T	1907	Missense	distal	-5	no	12.962	12.940	EPSD	COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q92793	CREBBP	P28482	MAPK1	S1912	P1905L	1905	Missense	distal	-7	no	12.962	12.950	EPSD	COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q92793	CREBBP	P28482	MAPK1	S1912	P1909L	1909	Missense	distal	-3	no	12.962	12.579	EPSD	COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q92793	CREBBP	P28482	MAPK1	S1912	P1913L	1913	Missense	proximal	1	no	12.962	4.153	EPSD	COSMIC	8.102	Loss
CMGC_MAPK_ERK1_MAPK1_ST	Q92793	CREBBP	P28482	MAPK1	T1990	R1985L	1985	Missense	distal	-5	no	12.024	12.125	EPSD	COSMIC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q92793	CREBBP	P28482	MAPK1	T1990	P1997L	1997	Missense	distal	7	no	12.024	12.323	EPSD	COSMIC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q92793	CREBBP	P28482	MAPK1	T1990	P1991L	1991	Missense	proximal	1	no	12.024	3.214	EPSD	COSMIC	8.102	Loss
CMGC_MAPK_ERK1_MAPK1_ST	Q92793	CREBBP	P28482	MAPK1	T1990	R1985H	1985	Missense	distal	-5	no	12.024	12.101	EPSD	COSMIC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q92793	CREBBP	P28482	MAPK1	T1990	A1996V	1996	Missense	distal	6	no	12.024	12.105	EPSD	COSMIC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q92793	CREBBP	P28482	MAPK1	S1993	P1997L	1997	Missense	distal	4	no	8.530	8.410	EPSD	COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q92793	CREBBP	P28482	MAPK1	S1993	P1991L	1991	Missense	proximal	-2	no	8.530	6.613	EPSD	COSMIC	8.102	Loss
CMGC_MAPK_ERK1_MAPK1_ST	Q92793	CREBBP	P28482	MAPK1	S1993	A1996V	1996	Missense	distal	3	no	8.530	8.509	EPSD	COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q92793	CREBBP	P28482	MAPK1	S2063	V2056M	2056	Missense	distal	-7	no	13.590	13.587	EPSD	COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q92793	CREBBP	P28482	MAPK1	S2063	S2065N	2065	Missense	proximal	2	no	13.590	13.542	EPSD	COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q92793	CREBBP	P28482	MAPK1	S2076	S2076L	2076	Missense	central	0	yes	13.145	0.000	EPSD	COSMIC;GDSC;CCLE	8.102	Loss
CMGC_MAPK_ERK1_MAPK1_ST	Q92793	CREBBP	P28482	MAPK1	S2079	S2076L	2076	Missense	distal	-3	no	16.458	16.251	EPSD	COSMIC;GDSC;CCLE	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q92793	CREBBP	P28482	MAPK1	S2307	P2311L	2311	Missense	distal	4	no	14.864	14.743	EPSD	COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q92793	CREBBP	P28482	MAPK1	S2307	P2313L	2313	Missense	distal	6	no	14.864	14.457	EPSD	COSMIC;GDSC;CCLE	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q92793	CREBBP	P28482	MAPK1	S2307	G2306V	2306	Missense	proximal	-1	no	14.864	14.892	EPSD	COSMIC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q92793	CREBBP	P28482	MAPK1	S2307	S2307F	2307	Missense	central	0	yes	14.864	0.000	EPSD	COSMIC	8.102	Loss
CMGC_MAPK_ERK1_MAPK1_ST	Q92793	CREBBP	P28482	MAPK1	S2307	P2308L	2308	Missense	proximal	1	no	14.864	6.054	EPSD	COSMIC	8.102	Loss
CMGC_MAPK_ERK1_MAPK1_ST	Q92793	CREBBP	P28482	MAPK1	S2315	Q2318E	2318	Missense	distal	3	no	15.289	15.212	EPSD	COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q92793	CREBBP	P28482	MAPK1	S2315	P2311L	2311	Missense	distal	-4	no	15.289	14.985	EPSD	COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q92793	CREBBP	P28482	MAPK1	S2315	P2313L	2313	Missense	proximal	-2	no	15.289	13.372	EPSD	COSMIC;GDSC;CCLE	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q92793	CREBBP	P28482	MAPK1	S2315	S2322L	2322	Missense	distal	7	no	15.289	15.578	EPSD	COSMIC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q92793	CREBBP	P28482	MAPK1	S2315	P2308L	2308	Missense	distal	-7	no	15.289	15.277	EPSD	COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q92793	CREBBP	P28482	MAPK1	S2345	P2352L	2352	Missense	distal	7	no	13.537	13.836	EPSD	COSMIC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q92793	CREBBP	P28482	MAPK1	S2345	N2341K	2341	Missense	distal	-4	no	13.537	13.568	EPSD	COSMIC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q92793	CREBBP	P28482	MAPK1	S2345	P2346L	2346	Missense	proximal	1	no	13.537	4.727	EPSD	COSMIC	8.102	Loss
CMGC_MAPK_ERK1_MAPK1_ST	Q92793	CREBBP	P28482	MAPK1	S2345	S2338C	2338	Missense	distal	-7	no	13.537	13.504	EPSD	COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q92793	CREBBP	P28482	MAPK1	S2345	S2345F	2345	Missense	central	0	yes	13.537	0.000	EPSD	COSMIC	8.102	Loss
CMGC_MAPK_ERK1_MAPK1_ST	Q92793	CREBBP	P28482	MAPK1	S2351	P2358S	2358	Missense	distal	7	no	16.238	16.249	EPSD	COSMIC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q92793	CREBBP	P28482	MAPK1	S2351	P2352L	2352	Missense	proximal	1	no	16.238	7.429	EPSD	COSMIC	8.102	Loss
CMGC_MAPK_ERK1_MAPK1_ST	Q92793	CREBBP	P28482	MAPK1	S2351	P2346L	2346	Missense	distal	-5	no	16.238	16.387	EPSD	COSMIC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q92793	CREBBP	P28482	MAPK1	S2351	S2356P	2356	Missense	distal	5	no	16.238	16.220	EPSD	COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q92793	CREBBP	P28482	MAPK1	S2351	R2353W	2353	Missense	proximal	2	no	16.238	15.870	EPSD	COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q92793	CREBBP	P28482	MAPK1	S2351	S2345F	2345	Missense	distal	-6	no	16.238	16.154	EPSD	COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q92793	CREBBP	P28482	MAPK1	S2362	P2358S	2358	Missense	distal	-4	no	13.050	12.967	EPSD	COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q92793	CREBBP	P28482	MAPK1	S2362	P2369T	2369	Missense	distal	7	no	13.050	13.213	EPSD	COSMIC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q92793	CREBBP	P28482	MAPK1	S2362	P2363L	2363	Missense	proximal	1	no	13.050	4.241	EPSD	COSMIC	8.102	Loss
CMGC_MAPK_ERK1_MAPK1_ST	Q92793	CREBBP	P28482	MAPK1	S2362	S2361F	2361	Missense	proximal	-1	no	13.050	13.004	EPSD	COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q92793	CREBBP	P28482	MAPK1	S2362	R2366W	2366	Missense	distal	4	no	13.050	12.767	EPSD	COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q92793	CREBBP	P28482	MAPK1	S2362	S2356P	2356	Missense	distal	-6	no	13.050	13.076	EPSD	COSMIC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q92793	CREBBP	P28482	MAPK1	S2362	R2366Q	2366	Missense	distal	4	no	13.050	12.976	EPSD	COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q92793	CREBBP	P28482	MAPK1	S2364	P2358S	2358	Missense	distal	-6	no	14.289	14.263	EPSD	COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q92793	CREBBP	P28482	MAPK1	S2364	P2369T	2369	Missense	distal	5	no	14.289	14.233	EPSD	COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q92793	CREBBP	P28482	MAPK1	S2364	P2363L	2363	Missense	proximal	-1	no	14.289	14.229	EPSD	COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q92793	CREBBP	P28482	MAPK1	S2364	S2361F	2361	Missense	distal	-3	no	14.289	14.056	EPSD	COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q92793	CREBBP	P28482	MAPK1	S2364	R2366W	2366	Missense	proximal	2	no	14.289	13.920	EPSD	COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q92793	CREBBP	P28482	MAPK1	S2364	R2366Q	2366	Missense	proximal	2	no	14.289	13.997	EPSD	COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q92793	CREBBP	P28482	MAPK1	S2372	S2377L	2377	Missense	distal	5	no	15.012	14.781	EPSD	COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q92793	CREBBP	P28482	MAPK1	S2372	P2369T	2369	Missense	distal	-3	no	15.012	14.802	EPSD	COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q92793	CREBBP	P28482	MAPK1	S2372	S2372W	2372	Missense	central	0	yes	15.012	0.000	EPSD	COSMIC	8.102	Loss
CMGC_MAPK_ERK1_MAPK1_ST	Q92793	CREBBP	P28482	MAPK1	S2372	R2366W	2366	Missense	distal	-6	no	15.012	14.791	EPSD	COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q92793	CREBBP	P28482	MAPK1	S2372	R2366Q	2366	Missense	distal	-6	no	15.012	14.988	EPSD	COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q92793	CREBBP	P28482	MAPK1	S2372	Q2379H	2379	Missense	distal	7	no	15.012	15.116	EPSD	COSMIC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q92793	CREBBP	P28482	MAPK1	S2377	S2377L	2377	Missense	central	0	yes	13.072	0.000	EPSD	COSMIC	8.102	Loss
CMGC_MAPK_ERK1_MAPK1_ST	Q92793	CREBBP	P28482	MAPK1	S2377	H2384R	2384	Missense	distal	7	no	13.072	12.853	EPSD	COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q92793	CREBBP	P28482	MAPK1	S2377	P2383L	2383	Missense	distal	6	no	13.072	12.666	EPSD	COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q92793	CREBBP	P28482	MAPK1	S2377	S2372W	2372	Missense	distal	-5	no	13.072	13.322	EPSD	COSMIC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q92793	CREBBP	P28482	MAPK1	S2377	H2384N	2384	Missense	distal	7	no	13.072	12.832	EPSD	COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q92793	CREBBP	P28482	MAPK1	S2377	Q2379H	2379	Missense	proximal	2	no	13.072	13.120	EPSD	COSMIC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q92793	CREBBP	P28482	MAPK1	S2382	S2377L	2377	Missense	distal	-5	no	13.983	14.058	EPSD	COSMIC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q92793	CREBBP	P28482	MAPK1	S2382	H2384R	2384	Missense	proximal	2	no	13.983	14.227	EPSD	COSMIC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q92793	CREBBP	P28482	MAPK1	S2382	P2383L	2383	Missense	proximal	1	no	13.983	5.174	EPSD	COSMIC	8.102	Loss
CMGC_MAPK_ERK1_MAPK1_ST	Q92793	CREBBP	P28482	MAPK1	S2382	P2383S	2383	Missense	proximal	1	no	13.983	4.589	EPSD	COSMIC	8.102	Loss
CMGC_MAPK_ERK1_MAPK1_ST	Q92793	CREBBP	P28482	MAPK1	S2382	H2384N	2384	Missense	proximal	2	no	13.983	14.037	EPSD	COSMIC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q92793	CREBBP	P28482	MAPK1	S2382	P2385S	2385	Missense	distal	3	no	13.983	14.053	EPSD	COSMIC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q92793	CREBBP	P28482	MAPK1	S2382	Q2379H	2379	Missense	distal	-3	no	13.983	13.931	EPSD	COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q92793	CREBBP	P28482	MAPK1	T2414	P2415L	2415	Missense	proximal	1	no	15.013	6.204	EPSD	COSMIC	8.102	Loss
CMGC_MAPK_ERK1_MAPK1_ST	Q92793	CREBBP	P28482	MAPK1	T2414	P2410S	2410	Missense	distal	-4	no	15.013	14.930	EPSD	COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q92793	CREBBP	P28482	MAPK1	T2414	A2419V	2419	Missense	distal	5	no	15.013	15.030	EPSD	COSMIC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q92793	CREBBP	P28482	MAPK1	T2414	M2408V	2408	Missense	distal	-6	no	15.013	15.011	EPSD	COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q92793	CREBBP	P28482	MAPK1	T2414	L2409H	2409	Missense	distal	-5	no	15.013	14.989	EPSD	COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q92793	CREBBP	P28482	MAPK1	T2414	S2421F	2421	Missense	distal	7	no	15.013	15.361	EPSD	COSMIC;GDSC;CCLE	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q92793	CREBBP	P28482	MAPK1	S2425	A2419V	2419	Missense	distal	-6	no	9.116	9.068	EPSD	COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q92793	CREBBP	P28482	MAPK1	S2425	D2429Y	2429	Missense	distal	4	no	9.116	9.018	EPSD	COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q92793	CREBBP	P28482	MAPK1	S2425	S2421F	2421	Missense	distal	-4	no	9.116	8.855	EPSD	COSMIC;GDSC;CCLE	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P32121	ARRB2	P28482	MAPK1	S14	V21M	21	Missense	distal	7	no	17.527	17.604	PhosphoSitePlus;EPSD	COSMIC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P32121	ARRB2	P28482	MAPK1	S267	D260V	260	Missense	distal	-7	no	9.379	9.363	EPSD	COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P32121	ARRB2	P28482	MAPK1	S267	T268I	268	Missense	proximal	1	no	9.379	8.060	EPSD	COSMIC	8.102	Loss
CMGC_MAPK_ERK1_MAPK1_ST	P32121	ARRB2	P28482	MAPK1	S267	S267N	267	Missense	central	0	yes	9.379	0.000	EPSD	COSMIC	8.102	Loss
CMGC_MAPK_ERK1_MAPK1_ST	P32121	ARRB2	P28482	MAPK1	T276	R283Q	283	Missense	distal	7	no	12.353	12.469	EPSD;PhosphoSitePlus	COSMIC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P32121	ARRB2	P28482	MAPK1	T276	R283W	283	Missense	distal	7	no	12.353	13.325	EPSD;PhosphoSitePlus	COSMIC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P32121	ARRB2	P28482	MAPK1	T276	D281V	281	Missense	distal	5	no	12.353	12.186	EPSD;PhosphoSitePlus	COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P32121	ARRB2	P28482	MAPK1	T276	T276I	276	Missense	central	0	yes	12.353	0.000	EPSD;PhosphoSitePlus	COSMIC	8.102	Loss
CMGC_MAPK_ERK1_MAPK1_ST	P32121	ARRB2	P28482	MAPK1	S360	P356L	356	Missense	distal	-4	no	11.077	10.772	EPSD	COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P32121	ARRB2	P28482	MAPK1	S360	A361V	361	Missense	proximal	1	no	11.077	9.166	EPSD	COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P32121	ARRB2	P28482	MAPK1	S360	P356T	356	Missense	distal	-4	no	11.077	10.763	EPSD	COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P32121	ARRB2	P28482	MAPK1	S360	P356S	356	Missense	distal	-4	no	11.077	10.993	EPSD	COSMIC;CCLE	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q96RS0	TGS1	P28482	MAPK1	S141	Q139R	139	Missense	proximal	-2	no	6.967	8.142	EPSD	COSMIC	8.102	Gain
CMGC_MAPK_ERK1_MAPK1_ST	Q96RS0	TGS1	P28482	MAPK1	S189	P183A	183	Missense	distal	-6	no	13.150	13.110	EPSD	COSMIC;CCLE	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q96RS0	TGS1	P28482	MAPK1	S294	L292V	292	Missense	proximal	-2	no	9.516	9.561	EPSD	COSMIC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q96RS0	TGS1	P28482	MAPK1	S298	L292V	292	Missense	distal	-6	no	18.074	18.080	PhosphoSitePlus	COSMIC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q96RS0	TGS1	P28482	MAPK1	S306	S307F	307	Missense	proximal	1	no	5.308	8.133	EPSD	COSMIC	8.102	Gain
CMGC_MAPK_ERK1_MAPK1_ST	Q96RS0	TGS1	P28482	MAPK1	S438	G444C	444	Missense	distal	6	no	8.666	7.876	EPSD	COSMIC	8.102	Loss
CMGC_MAPK_ERK1_MAPK1_ST	Q01196	RUNX1	P28482	MAPK1	T14	T14M	14	Missense	central	0	yes	15.799	0.000	EPSD	COSMIC	8.102	Loss
CMGC_MAPK_ERK1_MAPK1_ST	Q01196	RUNX1	P28482	MAPK1	S17	K24N	24	Missense	distal	7	no	10.375	10.409	EPSD	COSMIC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q01196	RUNX1	P28482	MAPK1	S17	P22L	22	Missense	distal	5	no	10.375	10.161	EPSD	COSMIC;CCLE	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q01196	RUNX1	P28482	MAPK1	S17	P22Q	22	Missense	distal	5	no	10.375	10.254	EPSD	COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q01196	RUNX1	P28482	MAPK1	S17	T14M	14	Missense	distal	-3	no	10.375	10.146	EPSD	COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q01196	RUNX1	P28482	MAPK1	T18	K24N	24	Missense	distal	6	no	11.762	11.609	EPSD	COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q01196	RUNX1	P28482	MAPK1	T18	M25K	25	Missense	distal	7	no	11.762	11.351	EPSD	COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q01196	RUNX1	P28482	MAPK1	T18	P22L	22	Missense	distal	4	no	11.762	11.642	EPSD	COSMIC;CCLE	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q01196	RUNX1	P28482	MAPK1	T18	P22Q	22	Missense	distal	4	no	11.762	11.654	EPSD	COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q01196	RUNX1	P28482	MAPK1	T18	T14M	14	Missense	distal	-4	no	11.762	11.610	EPSD	COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q01196	RUNX1	P28482	MAPK1	S21	K24N	24	Missense	distal	3	no	16.738	16.731	EPSD	COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q01196	RUNX1	P28482	MAPK1	S21	M25K	25	Missense	distal	4	no	16.738	16.913	EPSD	COSMIC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q01196	RUNX1	P28482	MAPK1	S21	E27Q	27	Missense	distal	6	no	16.738	16.417	EPSD	COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q01196	RUNX1	P28482	MAPK1	S21	A28E	28	Missense	distal	7	no	16.738	16.498	EPSD	COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q01196	RUNX1	P28482	MAPK1	S21	P22L	22	Missense	proximal	1	no	16.738	7.928	EPSD	COSMIC;CCLE	8.102	Loss
CMGC_MAPK_ERK1_MAPK1_ST	Q01196	RUNX1	P28482	MAPK1	S21	P22Q	22	Missense	proximal	1	no	16.738	8.244	EPSD	COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q01196	RUNX1	P28482	MAPK1	S21	E27K	27	Missense	distal	6	no	16.738	16.761	EPSD	COSMIC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q01196	RUNX1	P28482	MAPK1	S21	T14M	14	Missense	distal	-7	no	16.738	16.733	EPSD	COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q01196	RUNX1	P28482	MAPK1	S67	L71M	71	Missense	distal	4	no	13.305	13.227	EPSD	COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q01196	RUNX1	P28482	MAPK1	S67	V63A	63	Missense	distal	-4	no	13.305	13.366	EPSD	COSMIC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q01196	RUNX1	P28482	MAPK1	S67	L62R	62	Missense	distal	-5	no	13.305	13.204	EPSD	COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q01196	RUNX1	P28482	MAPK1	S67	F70Y	70	Missense	distal	3	no	13.305	13.301	EPSD	COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q01196	RUNX1	P28482	MAPK1	S67	F70L	70	Missense	distal	3	no	13.305	13.263	EPSD	COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q01196	RUNX1	P28482	MAPK1	S67	T65A	65	Missense	proximal	-2	no	13.305	12.858	EPSD	COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q01196	RUNX1	P28482	MAPK1	S67	S73F	73	Missense	distal	6	no	13.305	12.864	EPSD	COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q01196	RUNX1	P28482	MAPK1	S67	D66N	66	Missense	proximal	-1	no	13.305	13.366	EPSD	COSMIC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q01196	RUNX1	P28482	MAPK1	S67	C72Y	72	Missense	distal	5	no	13.305	13.416	EPSD	COSMIC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q01196	RUNX1	P28482	MAPK1	S67	N69S	69	Missense	proximal	2	no	13.305	13.353	EPSD	COSMIC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q01196	RUNX1	P28482	MAPK1	S67	P68L	68	Missense	proximal	1	no	13.305	4.495	EPSD	COSMIC	8.102	Loss
CMGC_MAPK_ERK1_MAPK1_ST	Q01196	RUNX1	P28482	MAPK1	S67	S67I	67	Missense	central	0	yes	13.305	0.000	EPSD	COSMIC	8.102	Loss
CMGC_MAPK_ERK1_MAPK1_ST	Q01196	RUNX1	P28482	MAPK1	S67	E61K	61	Missense	distal	-6	no	13.305	13.279	EPSD	COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q01196	RUNX1	P28482	MAPK1	S67	S67R	67	Missense	central	0	yes	13.305	0.000	EPSD	COSMIC;CCLE	8.102	Loss
CMGC_MAPK_ERK1_MAPK1_ST	Q01196	RUNX1	P28482	MAPK1	S67	S73C	73	Missense	distal	6	no	13.305	12.438	EPSD	COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q01196	RUNX1	P28482	MAPK1	S67	F70S	70	Missense	distal	3	no	13.305	13.243	EPSD	COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q01196	RUNX1	P28482	MAPK1	S67	D66Y	66	Missense	proximal	-1	no	13.305	13.285	EPSD	COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q01196	RUNX1	P28482	MAPK1	T84	L85P	85	Missense	proximal	1	no	3.252	12.061	EPSD	COSMIC	8.102	Gain
CMGC_MAPK_ERK1_MAPK1_ST	Q01196	RUNX1	P28482	MAPK1	S145	G143R	143	Missense	proximal	-2	no	6.766	8.142	EPSD	COSMIC	8.102	Gain
CMGC_MAPK_ERK1_MAPK1_ST	Q01196	RUNX1	P28482	MAPK1	T147	L148P	148	Missense	proximal	1	no	4.866	13.676	EPSD	COSMIC	8.102	Gain
CMGC_MAPK_ERK1_MAPK1_ST	Q01196	RUNX1	P28482	MAPK1	S212	A208G	208	Missense	distal	-4	no	15.977	15.920	EPSD	COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q01196	RUNX1	P28482	MAPK1	S212	S212L	212	Missense	central	0	yes	15.977	0.000	EPSD	COSMIC	8.102	Loss
CMGC_MAPK_ERK1_MAPK1_ST	Q01196	RUNX1	P28482	MAPK1	S212	R205Q	205	Missense	distal	-7	no	15.977	15.985	EPSD	COSMIC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q01196	RUNX1	P28482	MAPK1	S212	R205L	205	Missense	distal	-7	no	15.977	15.970	EPSD	COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q01196	RUNX1	P28482	MAPK1	S212	R210K	210	Missense	proximal	-2	no	15.977	15.376	EPSD	COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q01196	RUNX1	P28482	MAPK1	S212	T219M	219	Missense	distal	7	no	15.977	16.184	EPSD	COSMIC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q01196	RUNX1	P28482	MAPK1	S212	A208V	208	Missense	distal	-4	no	15.977	15.916	EPSD	COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q01196	RUNX1	P28482	MAPK1	S212	R205W	205	Missense	distal	-7	no	15.977	15.926	EPSD	COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q01196	RUNX1	P28482	MAPK1	S212	P216L	216	Missense	distal	4	no	15.977	15.856	EPSD	COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q01196	RUNX1	P28482	MAPK1	S212	A208T	208	Missense	distal	-4	no	15.977	15.957	EPSD	COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q01196	RUNX1	P28482	MAPK1	S212	A217V	217	Missense	distal	5	no	15.977	15.994	EPSD	COSMIC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q01196	RUNX1	P28482	MAPK1	S212	R206H	206	Missense	distal	-6	no	15.977	15.894	EPSD	COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q01196	RUNX1	P28482	MAPK1	S212	P218L	218	Missense	distal	6	no	15.977	15.570	EPSD	COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q01196	RUNX1	P28482	MAPK1	S212	V211A	211	Missense	proximal	-1	no	15.977	15.966	EPSD	COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q01196	RUNX1	P28482	MAPK1	S212	M209I	209	Missense	distal	-3	no	15.977	15.973	EPSD	COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q01196	RUNX1	P28482	MAPK1	T219	L226F	226	Missense	distal	7	no	13.327	13.386	EPSD	COSMIC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q01196	RUNX1	P28482	MAPK1	T219	S212L	212	Missense	distal	-7	no	13.327	13.319	EPSD	COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q01196	RUNX1	P28482	MAPK1	T219	A224V	224	Missense	distal	5	no	13.327	13.344	EPSD	COSMIC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q01196	RUNX1	P28482	MAPK1	T219	R223C	223	Missense	distal	4	no	13.327	13.068	EPSD	COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q01196	RUNX1	P28482	MAPK1	T219	T219M	219	Missense	central	0	yes	13.327	0.000	EPSD	COSMIC	8.102	Loss
CMGC_MAPK_ERK1_MAPK1_ST	Q01196	RUNX1	P28482	MAPK1	T219	S225F	225	Missense	distal	6	no	13.327	12.886	EPSD	COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q01196	RUNX1	P28482	MAPK1	T219	P218S	218	Missense	proximal	-1	no	13.327	13.284	EPSD	COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q01196	RUNX1	P28482	MAPK1	T219	A224T	224	Missense	distal	5	no	13.327	13.413	EPSD	COSMIC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q01196	RUNX1	P28482	MAPK1	T219	P216L	216	Missense	distal	-3	no	13.327	12.943	EPSD	COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q01196	RUNX1	P28482	MAPK1	T219	A217V	217	Missense	proximal	-2	no	13.327	14.601	EPSD	COSMIC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q01196	RUNX1	P28482	MAPK1	T219	R223P	223	Missense	distal	4	no	13.327	13.360	EPSD	COSMIC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q01196	RUNX1	P28482	MAPK1	T219	P218L	218	Missense	proximal	-1	no	13.327	13.267	EPSD	COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q01196	RUNX1	P28482	MAPK1	T219	R223H	223	Missense	distal	4	no	13.327	13.185	EPSD	COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q01196	RUNX1	P28482	MAPK1	T219	P222S	222	Missense	distal	3	no	13.327	13.396	EPSD	COSMIC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q01196	RUNX1	P28482	MAPK1	S225	L226F	226	Missense	proximal	1	no	6.671	8.911	EPSD	COSMIC	8.102	Gain
CMGC_MAPK_ERK1_MAPK1_ST	Q01196	RUNX1	P28482	MAPK1	S225	R223P	223	Missense	proximal	-2	no	6.671	8.489	EPSD	COSMIC	8.102	Gain
CMGC_MAPK_ERK1_MAPK1_ST	Q01196	RUNX1	P28482	MAPK1	S249	T243I	243	Missense	distal	-6	no	12.250	12.173	EPSD	COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q01196	RUNX1	P28482	MAPK1	S249	P250L	250	Missense	proximal	1	no	12.250	3.441	EPSD	COSMIC	8.102	Loss
CMGC_MAPK_ERK1_MAPK1_ST	Q01196	RUNX1	P28482	MAPK1	S249	P251L	251	Missense	proximal	2	no	12.250	12.103	EPSD	COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q01196	RUNX1	P28482	MAPK1	S249	T243K	243	Missense	distal	-6	no	12.250	12.285	EPSD	COSMIC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q01196	RUNX1	P28482	MAPK1	S253	P250L	250	Missense	distal	-3	no	9.792	9.408	EPSD	COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q01196	RUNX1	P28482	MAPK1	S253	P251L	251	Missense	proximal	-2	no	9.792	7.875	EPSD	COSMIC	8.102	Loss
CMGC_MAPK_ERK1_MAPK1_ST	Q01196	RUNX1	P28482	MAPK1	S253	Y260F	260	Missense	distal	7	no	9.792	9.622	EPSD	COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q01196	RUNX1	P28482	MAPK1	S253	Y258C	258	Missense	distal	5	no	9.792	9.681	EPSD	COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q01196	RUNX1	P28482	MAPK1	S266	S268F	268	Missense	proximal	2	no	12.764	12.632	EPSD	COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q01196	RUNX1	P28482	MAPK1	S266	P267S	267	Missense	proximal	1	no	12.764	3.369	EPSD	COSMIC	8.102	Loss
CMGC_MAPK_ERK1_MAPK1_ST	Q01196	RUNX1	P28482	MAPK1	S266	T273M	273	Missense	distal	7	no	12.764	12.971	EPSD	COSMIC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q01196	RUNX1	P28482	MAPK1	S266	G262R	262	Missense	distal	-4	no	12.764	13.024	EPSD	COSMIC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q01196	RUNX1	P28482	MAPK1	S266	P271Q	271	Missense	distal	5	no	12.764	12.644	EPSD	COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q01196	RUNX1	P28482	MAPK1	S266	Y260F	260	Missense	distal	-6	no	12.764	12.794	EPSD	COSMIC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q01196	RUNX1	P28482	MAPK1	S266	P271S	271	Missense	distal	5	no	12.764	12.782	EPSD	COSMIC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q01196	RUNX1	P28482	MAPK1	S266	A265S	265	Missense	proximal	-1	no	12.764	12.758	EPSD	COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q01196	RUNX1	P28482	MAPK1	S266	L261P	261	Missense	distal	-5	no	12.764	12.615	EPSD	COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q01196	RUNX1	P28482	MAPK1	S266	A272G	272	Missense	distal	6	no	12.764	12.983	EPSD	COSMIC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q01196	RUNX1	P28482	MAPK1	T273	P277L	277	Missense	distal	4	no	15.167	15.046	EPSD	COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q01196	RUNX1	P28482	MAPK1	T273	S268F	268	Missense	distal	-5	no	15.167	15.255	EPSD	COSMIC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q01196	RUNX1	P28482	MAPK1	T273	P267S	267	Missense	distal	-6	no	15.167	15.141	EPSD	COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q01196	RUNX1	P28482	MAPK1	T273	S276L	276	Missense	distal	3	no	15.167	15.187	EPSD	COSMIC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q01196	RUNX1	P28482	MAPK1	T273	T273M	273	Missense	central	0	yes	15.167	0.000	EPSD	COSMIC	8.102	Loss
CMGC_MAPK_ERK1_MAPK1_ST	Q01196	RUNX1	P28482	MAPK1	T273	P271Q	271	Missense	proximal	-2	no	15.167	12.173	EPSD	COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q01196	RUNX1	P28482	MAPK1	T273	P271S	271	Missense	proximal	-2	no	15.167	12.333	EPSD	COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q01196	RUNX1	P28482	MAPK1	T273	R279C	279	Missense	distal	6	no	15.167	14.407	EPSD	COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q01196	RUNX1	P28482	MAPK1	T273	A272G	272	Missense	proximal	-1	no	15.167	15.150	EPSD	COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q01196	RUNX1	P28482	MAPK1	T273	R279P	279	Missense	distal	6	no	15.167	15.274	EPSD	COSMIC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q01196	RUNX1	P28482	MAPK1	S276	P277L	277	Missense	proximal	1	no	17.372	8.562	PhosphoSitePlus;EPSD	COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q01196	RUNX1	P28482	MAPK1	S276	S276L	276	Missense	central	0	yes	17.372	0.000	PhosphoSitePlus;EPSD	COSMIC	8.102	Loss
CMGC_MAPK_ERK1_MAPK1_ST	Q01196	RUNX1	P28482	MAPK1	S276	T273M	273	Missense	distal	-3	no	17.372	17.144	PhosphoSitePlus;EPSD	COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q01196	RUNX1	P28482	MAPK1	S276	G282S	282	Missense	distal	6	no	17.372	17.449	PhosphoSitePlus;EPSD	COSMIC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q01196	RUNX1	P28482	MAPK1	S276	P271Q	271	Missense	distal	-5	no	17.372	17.497	PhosphoSitePlus;EPSD	COSMIC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q01196	RUNX1	P28482	MAPK1	S276	P271S	271	Missense	distal	-5	no	17.372	17.446	PhosphoSitePlus;EPSD	COSMIC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q01196	RUNX1	P28482	MAPK1	S276	R279C	279	Missense	distal	3	no	17.372	17.499	PhosphoSitePlus;EPSD	COSMIC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q01196	RUNX1	P28482	MAPK1	S276	A272G	272	Missense	distal	-4	no	17.372	17.315	PhosphoSitePlus;EPSD	COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q01196	RUNX1	P28482	MAPK1	S276	R279P	279	Missense	distal	3	no	17.372	17.326	PhosphoSitePlus;EPSD	COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q01196	RUNX1	P28482	MAPK1	S329	F326S	326	Missense	distal	-3	no	13.831	14.063	EPSD	COSMIC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q01196	RUNX1	P28482	MAPK1	S329	P323S	323	Missense	distal	-6	no	13.831	13.805	EPSD	COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q01196	RUNX1	P28482	MAPK1	S329	P332L	332	Missense	distal	3	no	13.831	13.920	EPSD	COSMIC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q01196	RUNX1	P28482	MAPK1	S329	S335L	335	Missense	distal	6	no	13.831	13.424	EPSD	COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q01196	RUNX1	P28482	MAPK1	T331	F326S	326	Missense	distal	-5	no	12.857	12.768	EPSD	COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q01196	RUNX1	P28482	MAPK1	T331	G338V	338	Missense	distal	7	no	12.857	13.071	EPSD	COSMIC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q01196	RUNX1	P28482	MAPK1	T331	P332L	332	Missense	proximal	1	no	12.857	4.047	EPSD	COSMIC	8.102	Loss
CMGC_MAPK_ERK1_MAPK1_ST	Q01196	RUNX1	P28482	MAPK1	T331	S335L	335	Missense	distal	4	no	12.857	12.747	EPSD	COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q01196	RUNX1	P28482	MAPK1	T334	G340D	340	Missense	distal	6	no	8.231	8.263	EPSD	COSMIC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q01196	RUNX1	P28482	MAPK1	T334	M341L	341	Missense	distal	7	no	8.231	8.160	EPSD	COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q01196	RUNX1	P28482	MAPK1	T334	G338V	338	Missense	distal	4	no	8.231	8.181	EPSD	COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q01196	RUNX1	P28482	MAPK1	T334	P332L	332	Missense	proximal	-2	no	8.231	6.314	EPSD	COSMIC	8.102	Loss
CMGC_MAPK_ERK1_MAPK1_ST	Q01196	RUNX1	P28482	MAPK1	T334	S335L	335	Missense	proximal	1	no	8.231	8.816	EPSD	COSMIC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q01196	RUNX1	P28482	MAPK1	S373	G367D	367	Missense	distal	-6	no	13.292	13.358	EPSD	COSMIC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q01196	RUNX1	P28482	MAPK1	S373	S373L	373	Missense	central	0	yes	13.292	0.000	EPSD	COSMIC	8.102	Loss
CMGC_MAPK_ERK1_MAPK1_ST	Q01196	RUNX1	P28482	MAPK1	S373	Q370R	370	Missense	distal	-3	no	13.292	13.569	EPSD	COSMIC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q01196	RUNX1	P28482	MAPK1	S373	P368M	368	Missense	distal	-5	no	13.292	13.445	EPSD	COSMIC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q01196	RUNX1	P28482	MAPK1	S373	Y380C	380	Missense	distal	7	no	13.292	13.434	EPSD	COSMIC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q01196	RUNX1	P28482	MAPK1	S373	S375F	375	Missense	proximal	2	no	13.292	13.161	EPSD	COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q01196	RUNX1	P28482	MAPK1	S373	G366A	366	Missense	distal	-7	no	13.292	13.308	EPSD	COSMIC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q01196	RUNX1	P28482	MAPK1	S373	F369I	369	Missense	distal	-4	no	13.292	12.966	EPSD	COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q01196	RUNX1	P28482	MAPK1	S373	P368L	368	Missense	distal	-5	no	13.292	13.441	EPSD	COSMIC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q01196	RUNX1	P28482	MAPK1	S375	S373L	373	Missense	proximal	-2	no	7.292	8.209	EPSD	COSMIC	8.102	Gain
CMGC_MAPK_ERK1_MAPK1_ST	Q01196	RUNX1	P28482	MAPK1	S397	G393A	393	Missense	distal	-4	no	15.300	15.356	EPSD	COSMIC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q01196	RUNX1	P28482	MAPK1	S397	E395K	395	Missense	proximal	-2	no	15.300	15.260	EPSD	COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q01196	RUNX1	P28482	MAPK1	S397	V392G	392	Missense	distal	-5	no	15.300	15.271	EPSD	COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q01196	RUNX1	P28482	MAPK1	S397	S397L	397	Missense	central	0	yes	15.300	0.000	EPSD	COSMIC	8.102	Loss
CMGC_MAPK_ERK1_MAPK1_ST	Q01196	RUNX1	P28482	MAPK1	S397	P398Q	398	Missense	proximal	1	no	15.300	6.806	EPSD	COSMIC	8.102	Loss
CMGC_MAPK_ERK1_MAPK1_ST	Q01196	RUNX1	P28482	MAPK1	S397	P398L	398	Missense	proximal	1	no	15.300	6.490	EPSD	COSMIC	8.102	Loss
CMGC_MAPK_ERK1_MAPK1_ST	Q01196	RUNX1	P28482	MAPK1	S397	R396H	396	Missense	proximal	-1	no	15.300	15.276	EPSD	COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q01196	RUNX1	P28482	MAPK1	S397	G394S	394	Missense	distal	-3	no	15.300	15.312	EPSD	COSMIC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q01196	RUNX1	P28482	MAPK1	S397	G393D	393	Missense	distal	-4	no	15.300	15.635	EPSD	COSMIC;CCLE	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q01196	RUNX1	P28482	MAPK1	S397	R400H	400	Missense	distal	3	no	15.300	15.342	EPSD	COSMIC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q01196	RUNX1	P28482	MAPK1	S397	P399T	399	Missense	proximal	2	no	15.300	15.249	EPSD	COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q01196	RUNX1	P28482	MAPK1	S397	R396P	396	Missense	proximal	-1	no	15.300	15.319	EPSD	COSMIC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q01196	RUNX1	P28482	MAPK1	S397	S390F	390	Missense	distal	-7	no	15.300	15.279	EPSD	COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q01196	RUNX1	P28482	MAPK1	S397	S397P	397	Missense	central	0	yes	15.300	0.000	EPSD	COSMIC	8.102	Loss
CMGC_MAPK_ERK1_MAPK1_ST	Q01196	RUNX1	P28482	MAPK1	S397	R396C	396	Missense	proximal	-1	no	15.300	15.197	EPSD	COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q01196	RUNX1	P28482	MAPK1	S397	S397A	397	Missense	central	0	yes	15.300	0.000	EPSD	COSMIC	8.102	Loss
CMGC_MAPK_ERK1_MAPK1_ST	Q01196	RUNX1	P28482	MAPK1	S431	E429D	429	Missense	proximal	-2	no	10.100	9.178	EPSD	COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q01196	RUNX1	P28482	MAPK1	S431	S433N	433	Missense	proximal	2	no	10.100	10.052	EPSD	COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q01196	RUNX1	P28482	MAPK1	S431	P436C	436	Missense	distal	5	no	10.100	9.719	EPSD	COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q01196	RUNX1	P28482	MAPK1	S431	V425M	425	Missense	distal	-6	no	10.100	10.103	EPSD	COSMIC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q01196	RUNX1	P28482	MAPK1	S431	E429K	429	Missense	proximal	-2	no	10.100	10.061	EPSD	COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q01196	RUNX1	P28482	MAPK1	S431	S431G	431	Missense	central	0	yes	10.100	0.000	EPSD	COSMIC	8.102	Loss
CMGC_MAPK_ERK1_MAPK1_ST	Q01196	RUNX1	P28482	MAPK1	S431	V426M	426	Missense	distal	-5	no	10.100	10.157	EPSD	COSMIC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q01196	RUNX1	P28482	MAPK1	S431	V426E	426	Missense	distal	-5	no	10.100	10.029	EPSD	COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q01196	RUNX1	P28482	MAPK1	S435	E429D	429	Missense	distal	-6	no	17.032	17.044	EPSD	COSMIC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q01196	RUNX1	P28482	MAPK1	S435	A440V	440	Missense	distal	5	no	17.032	17.049	EPSD	COSMIC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q01196	RUNX1	P28482	MAPK1	S435	S433N	433	Missense	proximal	-2	no	17.032	17.046	EPSD	COSMIC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q01196	RUNX1	P28482	MAPK1	S435	P436C	436	Missense	proximal	1	no	17.032	3.583	EPSD	COSMIC	8.102	Loss
CMGC_MAPK_ERK1_MAPK1_ST	Q01196	RUNX1	P28482	MAPK1	S435	S442F	442	Missense	distal	7	no	17.032	17.379	EPSD	COSMIC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q01196	RUNX1	P28482	MAPK1	S435	E429K	429	Missense	distal	-6	no	17.032	17.006	EPSD	COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q01196	RUNX1	P28482	MAPK1	S435	S431G	431	Missense	distal	-4	no	17.032	16.765	EPSD	COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q01196	RUNX1	P28482	MAPK1	S435	M439L	439	Missense	distal	4	no	17.032	17.110	EPSD	COSMIC;CCLE	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q01196	RUNX1	P28482	MAPK1	S435	M439T	439	Missense	distal	4	no	17.032	17.106	EPSD	COSMIC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q01196	RUNX1	P28482	MAPK1	S442	A440V	440	Missense	proximal	-2	no	7.944	9.218	EPSD	COSMIC	8.102	Gain
CMGC_MAPK_ERK1_MAPK1_ST	Q01196	RUNX1	P28482	MAPK1	S442	M439T	439	Missense	distal	-3	no	7.944	8.172	EPSD	COSMIC	8.102	Gain
CMGC_MAPK_ERK1_MAPK1_ST	Q01860	POU5F1	P28482	MAPK1	S12	A10S	10	Missense	proximal	-2	no	14.248	14.561	EPSD	COSMIC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q01860	POU5F1	P28482	MAPK1	T118	V122M	122	Missense	distal	4	no	14.457	14.368	PhosphoSitePlus;EPSD	COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q01860	POU5F1	P28482	MAPK1	T118	A121V	121	Missense	distal	3	no	14.457	14.436	PhosphoSitePlus;EPSD	COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P49795	RGS19	P28482	MAPK1	S24	R19L	19	Missense	distal	-5	no	8.902	9.003	EPSD	COSMIC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P49795	RGS19	P28482	MAPK1	S25	R19L	19	Missense	distal	-6	no	8.730	8.630	EPSD	COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P49795	RGS19	P28482	MAPK1	T78	E83V	83	Missense	distal	5	no	13.115	13.016	EPSD	COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P49795	RGS19	P28482	MAPK1	T78	T78M	78	Missense	central	0	yes	13.115	0.000	EPSD	COSMIC	8.102	Loss
CMGC_MAPK_ERK1_MAPK1_ST	P49795	RGS19	P28482	MAPK1	S80	E83V	83	Missense	distal	3	no	14.355	14.421	EPSD	COSMIC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P49795	RGS19	P28482	MAPK1	S80	T78M	78	Missense	proximal	-2	no	14.355	13.040	EPSD	COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P49795	RGS19	P28482	MAPK1	S151	K153M	153	Missense	proximal	2	no	15.124	15.000	PhosphoSitePlus	COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P49795	RGS19	P28482	MAPK1	S199	T201I	201	Missense	proximal	2	no	17.265	17.145	EPSD	COSMIC;GDSC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P49795	RGS19	P28482	MAPK1	S199	P200S	200	Missense	proximal	1	no	17.265	7.870	EPSD	COSMIC	8.102	Loss
CMGC_MAPK_ERK1_MAPK1_ST	P49795	RGS19	P28482	MAPK1	S199	R203H	203	Missense	distal	4	no	17.265	17.123	EPSD	COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P49795	RGS19	P28482	MAPK1	S199	R195C	195	Missense	distal	-4	no	17.265	16.627	EPSD	COSMIC;GDSC;CCLE	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P49795	RGS19	P28482	MAPK1	T201	T201I	201	Missense	central	0	yes	9.580	0.000	EPSD	COSMIC;GDSC	8.102	Loss
CMGC_MAPK_ERK1_MAPK1_ST	P49795	RGS19	P28482	MAPK1	T201	P200S	200	Missense	proximal	-1	no	9.580	9.537	EPSD	COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P49795	RGS19	P28482	MAPK1	T201	R203H	203	Missense	proximal	2	no	9.580	9.337	EPSD	COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P49795	RGS19	P28482	MAPK1	T201	R195C	195	Missense	distal	-6	no	9.580	9.405	EPSD	COSMIC;GDSC;CCLE	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P49795	RGS19	P28482	MAPK1	S213	S214F	214	Missense	proximal	1	no	7.040	9.865	EPSD	COSMIC	8.102	Gain
CMGC_MAPK_ERK1_MAPK1_ST	Q8NHW3	MAFA	P28482	MAPK1	S14	L11P	11	Missense	distal	-3	no	18.324	18.708	PhosphoSitePlus;EPSD	COSMIC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q9BUB5	MKNK1	P28482	MAPK1	S221	E220K	220	Missense	proximal	-1	no	11.453	11.481	EPSD	COSMIC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q9BUB5	MKNK1	P28482	MAPK1	S221	P214S	214	Missense	distal	-7	no	11.453	11.448	EPSD	COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q9BUB5	MKNK1	P28482	MAPK1	S221	N216I	216	Missense	distal	-5	no	11.453	11.636	EPSD	COSMIC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q9BUB5	MKNK1	P28482	MAPK1	S226	D232Y	232	Missense	distal	6	no	15.058	14.485	EPSD	COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q9BUB5	MKNK1	P28482	MAPK1	S226	E220K	220	Missense	distal	-6	no	15.058	15.032	EPSD	COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q9BUB5	MKNK1	P28482	MAPK1	T249	T249P	249	Missense	central	0	yes	8.525	0.000	EPSD	COSMIC	8.102	Loss
CMGC_MAPK_ERK1_MAPK1_ST	Q9BUB5	MKNK1	P28482	MAPK1	T249	T249I	249	Missense	central	0	yes	8.525	0.000	EPSD	COSMIC	8.102	Loss
CMGC_MAPK_ERK1_MAPK1_ST	Q9BUB5	MKNK1	P28482	MAPK1	T249	T254S	254	Missense	distal	5	no	8.525	8.599	EPSD	COSMIC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q9BUB5	MKNK1	P28482	MAPK1	T249	S244Y	244	Missense	distal	-5	no	8.525	8.656	EPSD	COSMIC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q9BUB5	MKNK1	P28482	MAPK1	T250	T249P	249	Missense	proximal	-1	no	14.132	14.174	EPSD	COSMIC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q9BUB5	MKNK1	P28482	MAPK1	T250	T249I	249	Missense	proximal	-1	no	14.132	14.108	EPSD	COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q9BUB5	MKNK1	P28482	MAPK1	T250	T254S	254	Missense	distal	4	no	14.132	14.245	EPSD	COSMIC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q9BUB5	MKNK1	P28482	MAPK1	T250	S244Y	244	Missense	distal	-6	no	14.132	14.018	EPSD	COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q9BUB5	MKNK1	P28482	MAPK1	T255	T249P	249	Missense	distal	-6	no	16.196	16.245	PhosphoSitePlus	COSMIC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q9BUB5	MKNK1	P28482	MAPK1	T255	G258D	258	Missense	distal	3	no	16.196	16.199	PhosphoSitePlus	COSMIC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q9BUB5	MKNK1	P28482	MAPK1	T255	T249I	249	Missense	distal	-6	no	16.196	16.118	PhosphoSitePlus	COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q9BUB5	MKNK1	P28482	MAPK1	T255	T254S	254	Missense	proximal	-1	no	16.196	16.195	PhosphoSitePlus	COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q9BUB5	MKNK1	P28482	MAPK1	T385	P384H	384	Missense	proximal	-1	no	13.507	13.464	EPSD	COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q9BUB5	MKNK1	P28482	MAPK1	T385	T385P	385	Missense	central	0	yes	13.507	0.000	EPSD	COSMIC	8.102	Loss
CMGC_MAPK_ERK1_MAPK1_ST	Q9BUB5	MKNK1	P28482	MAPK1	T385	P386L	386	Missense	proximal	1	no	13.507	4.697	EPSD	COSMIC;GDSC;CCLE	8.102	Loss
CMGC_MAPK_ERK1_MAPK1_ST	Q9BUB5	MKNK1	P28482	MAPK1	T385	L383P	383	Missense	proximal	-2	no	13.507	15.424	EPSD	COSMIC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q9BUB5	MKNK1	P28482	MAPK1	T385	L383F	383	Missense	proximal	-2	no	13.507	12.784	EPSD	COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q9BUB5	MKNK1	P28482	MAPK1	T385	P384L	384	Missense	proximal	-1	no	13.507	13.447	EPSD	COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q9BUB5	MKNK1	P28482	MAPK1	T385	K381E	381	Missense	distal	-4	no	13.507	13.489	EPSD	COSMIC;GDSC;CCLE	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q9BUB5	MKNK1	P28482	MAPK1	S437	L431P	431	Missense	distal	-6	no	14.974	15.066	EPSD	COSMIC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q9BUB5	MKNK1	P28482	MAPK1	S437	K435N	435	Missense	proximal	-2	no	14.974	14.574	EPSD	COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q9BUB5	MKNK1	P28482	MAPK1	S437	C440F	440	Missense	distal	3	no	14.974	14.933	EPSD	COSMIC;GDSC;CCLE	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q9BUB5	MKNK1	P28482	MAPK1	S460	P461L	461	Missense	proximal	1	no	16.116	7.306	EPSD	COSMIC	8.102	Loss
CMGC_MAPK_ERK1_MAPK1_ST	Q9BUB5	MKNK1	P28482	MAPK1	S460	G456V	456	Missense	distal	-4	no	16.116	16.112	EPSD	COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q9BUB5	MKNK1	P28482	MAPK1	T463	P461L	461	Missense	proximal	-2	no	8.107	6.190	EPSD	COSMIC	8.102	Loss
CMGC_MAPK_ERK1_MAPK1_ST	Q9BUB5	MKNK1	P28482	MAPK1	T463	G456V	456	Missense	distal	-7	no	8.107	8.106	EPSD	COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q96FF9	CDCA5	P28482	MAPK1	S21	R18K	18	Missense	distal	-3	no	16.770	16.532	EPSD	COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q96FF9	CDCA5	P28482	MAPK1	S21	G16R	16	Missense	distal	-5	no	16.770	16.750	EPSD	COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q96FF9	CDCA5	P28482	MAPK1	T48	T48I	48	Missense	central	0	yes	16.329	0.000	EPSD	COSMIC	8.102	Loss
CMGC_MAPK_ERK1_MAPK1_ST	Q96FF9	CDCA5	P28482	MAPK1	S75	V68I	68	Missense	distal	-7	no	15.275	15.262	EPSD	COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q96FF9	CDCA5	P28482	MAPK1	S75	R81S	81	Missense	distal	6	no	15.275	15.382	EPSD	COSMIC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q96FF9	CDCA5	P28482	MAPK1	S79	R81S	81	Missense	proximal	2	no	13.946	13.805	EPSD;PhosphoSitePlus	COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q96FF9	CDCA5	P28482	MAPK1	S83	R81S	81	Missense	proximal	-2	no	8.129	7.113	EPSD	COSMIC	8.102	Loss
CMGC_MAPK_ERK1_MAPK1_ST	Q96FF9	CDCA5	P28482	MAPK1	T111	P116F	116	Missense	distal	5	no	16.339	16.160	EPSD	COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q96FF9	CDCA5	P28482	MAPK1	S114	P116F	116	Missense	proximal	2	no	9.833	9.673	EPSD	COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q96FF9	CDCA5	P28482	MAPK1	T115	P116F	116	Missense	proximal	1	no	12.745	6.176	EPSD	COSMIC	8.102	Loss
CMGC_MAPK_ERK1_MAPK1_ST	Q96FF9	CDCA5	P28482	MAPK1	T159	G161S	161	Missense	proximal	2	no	11.368	11.322	EPSD	COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q96FF9	CDCA5	P28482	MAPK1	T159	S164F	164	Missense	distal	5	no	11.368	11.171	EPSD	COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q96FF9	CDCA5	P28482	MAPK1	S181	S181L	181	Missense	central	0	yes	13.703	0.000	EPSD	COSMIC	8.102	Loss
CMGC_MAPK_ERK1_MAPK1_ST	Q96FF9	CDCA5	P28482	MAPK1	S209	L205F	205	Missense	distal	-4	no	12.164	12.124	PhosphoSitePlus;EPSD	COSMIC;GDSC;CCLE	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q13625	TP53BP2	P28482	MAPK1	S71	D64G	64	Missense	distal	-7	no	8.808	8.793	EPSD	COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q13625	TP53BP2	P28482	MAPK1	S414	P415S	415	Missense	proximal	1	no	14.463	5.068	EPSD	COSMIC	8.102	Loss
CMGC_MAPK_ERK1_MAPK1_ST	Q13625	TP53BP2	P28482	MAPK1	S432	S432F	432	Missense	central	0	yes	9.436	0.000	EPSD	COSMIC	8.102	Loss
CMGC_MAPK_ERK1_MAPK1_ST	Q13625	TP53BP2	P28482	MAPK1	S530	Q531H	531	Missense	proximal	1	no	7.436	8.106	EPSD	COSMIC	8.102	Gain
CMGC_MAPK_ERK1_MAPK1_ST	Q13625	TP53BP2	P28482	MAPK1	S556	P557S	557	Missense	proximal	1	no	14.709	5.314	EPSD	COSMIC	8.102	Loss
CMGC_MAPK_ERK1_MAPK1_ST	Q13625	TP53BP2	P28482	MAPK1	S673	N666S	666	Missense	distal	-7	no	15.553	15.551	EPSD	COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q13625	TP53BP2	P28482	MAPK1	S698	S698C	698	Missense	central	0	yes	16.271	0.000	EPSD	COSMIC	8.102	Loss
CMGC_MAPK_ERK1_MAPK1_ST	Q13625	TP53BP2	P28482	MAPK1	S783	S776F	776	Missense	distal	-7	no	13.542	13.522	EPSD	COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P49137	MAPKAPK2	P28482	MAPK1	T25	P26L	26	Missense	proximal	1	no	18.005	9.195	EPSD;PhosphoSitePlus	COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P49137	MAPKAPK2	P28482	MAPK1	T25	L28P	28	Missense	distal	3	no	18.005	17.915	EPSD;PhosphoSitePlus	COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P49137	MAPKAPK2	P28482	MAPK1	T222	P223L	223	Missense	proximal	1	no	17.205	8.396	EPSD;PhosphoSitePlus	COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P49137	MAPKAPK2	P28482	MAPK1	T226	P223L	223	Missense	distal	-3	no	11.594	11.211	EPSD	COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P49137	MAPKAPK2	P28482	MAPK1	S272	G268S	268	Missense	distal	-4	no	15.974	16.240	EPSD;PhosphoSitePlus	COSMIC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P49137	MAPKAPK2	P28482	MAPK1	S272	R278H	278	Missense	distal	6	no	15.974	15.776	EPSD;PhosphoSitePlus	COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P49137	MAPKAPK2	P28482	MAPK1	T334	R340Q	340	Missense	distal	6	no	15.495	15.315	EPSD;PhosphoSitePlus	COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P49137	MAPKAPK2	P28482	MAPK1	T334	P335S	335	Missense	proximal	1	no	15.495	6.100	EPSD;PhosphoSitePlus	COSMIC	8.102	Loss
CMGC_MAPK_ERK1_MAPK1_ST	P49137	MAPKAPK2	P28482	MAPK1	T334	T329I	329	Missense	distal	-5	no	15.495	15.602	EPSD;PhosphoSitePlus	COSMIC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P23396	RPS3	P28482	MAPK1	T42	P43S	43	Missense	proximal	1	no	15.923	6.529	PhosphoSitePlus	COSMIC	8.102	Loss
CMGC_MAPK_ERK1_MAPK1_ST	P23396	RPS3	P28482	MAPK1	T242	P241S	241	Missense	proximal	-1	no	8.846	8.802	EPSD	COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P23396	RPS3	P28482	MAPK1	T242	M236T	236	Missense	distal	-6	no	8.846	8.880	EPSD	COSMIC;GDSC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q5JQC9	AKAP4	P28482	MAPK1	S19	R18S	18	Missense	proximal	-1	no	9.228	9.204	EPSD	COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q5JQC9	AKAP4	P28482	MAPK1	S19	R18C	18	Missense	proximal	-1	no	9.228	9.125	EPSD	COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q5JQC9	AKAP4	P28482	MAPK1	S130	L123V	123	Missense	distal	-7	no	11.858	11.851	EPSD	COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q5JQC9	AKAP4	P28482	MAPK1	S130	T135N	135	Missense	distal	5	no	11.858	11.859	EPSD	COSMIC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q5JQC9	AKAP4	P28482	MAPK1	T143	G141V	141	Missense	proximal	-2	no	6.856	8.177	EPSD	COSMIC	8.102	Gain
CMGC_MAPK_ERK1_MAPK1_ST	Q5JQC9	AKAP4	P28482	MAPK1	S190	P191L	191	Missense	proximal	1	no	14.195	5.385	EPSD	COSMIC	8.102	Loss
CMGC_MAPK_ERK1_MAPK1_ST	Q5JQC9	AKAP4	P28482	MAPK1	S190	Q189K	189	Missense	proximal	-1	no	14.195	14.249	EPSD	COSMIC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q5JQC9	AKAP4	P28482	MAPK1	S190	P195S	195	Missense	distal	5	no	14.195	14.213	EPSD	COSMIC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q5JQC9	AKAP4	P28482	MAPK1	T201	P199S	199	Missense	proximal	-2	no	8.986	6.152	EPSD	COSMIC	8.102	Loss
CMGC_MAPK_ERK1_MAPK1_ST	Q5JQC9	AKAP4	P28482	MAPK1	T201	P195S	195	Missense	distal	-6	no	8.986	8.960	EPSD	COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q5JQC9	AKAP4	P28482	MAPK1	S207	C212S	212	Missense	distal	5	no	15.036	15.436	EPSD	COSMIC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q5JQC9	AKAP4	P28482	MAPK1	S254	H248Y	248	Missense	distal	-6	no	14.098	14.032	EPSD	COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q5JQC9	AKAP4	P28482	MAPK1	S254	P253S	253	Missense	proximal	-1	no	14.098	14.054	EPSD	COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q5JQC9	AKAP4	P28482	MAPK1	S254	S254F	254	Missense	central	0	yes	14.098	0.000	EPSD	COSMIC	8.102	Loss
CMGC_MAPK_ERK1_MAPK1_ST	Q5JQC9	AKAP4	P28482	MAPK1	S254	E259K	259	Missense	distal	5	no	14.098	14.038	EPSD	COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q5JQC9	AKAP4	P28482	MAPK1	S262	P263T	263	Missense	proximal	1	no	15.486	6.987	EPSD	COSMIC	8.102	Loss
CMGC_MAPK_ERK1_MAPK1_ST	Q5JQC9	AKAP4	P28482	MAPK1	S262	A267V	267	Missense	distal	5	no	15.486	15.503	EPSD	COSMIC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q5JQC9	AKAP4	P28482	MAPK1	S262	E259K	259	Missense	distal	-3	no	15.486	15.408	EPSD	COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q5JQC9	AKAP4	P28482	MAPK1	T265	P263T	263	Missense	proximal	-2	no	14.857	12.158	PhosphoSitePlus	COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q5JQC9	AKAP4	P28482	MAPK1	T265	A267V	267	Missense	proximal	2	no	14.857	14.933	PhosphoSitePlus	COSMIC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q5JQC9	AKAP4	P28482	MAPK1	T265	E259K	259	Missense	distal	-6	no	14.857	14.832	PhosphoSitePlus	COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q5JQC9	AKAP4	P28482	MAPK1	S364	I361T	361	Missense	distal	-3	no	8.230	8.462	EPSD	COSMIC;GDSC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q5JQC9	AKAP4	P28482	MAPK1	S364	P362S	362	Missense	proximal	-2	no	8.230	5.396	EPSD	COSMIC	8.102	Loss
CMGC_MAPK_ERK1_MAPK1_ST	Q5JQC9	AKAP4	P28482	MAPK1	S489	C487R	487	Missense	proximal	-2	no	7.173	9.121	EPSD	COSMIC	8.102	Gain
CMGC_MAPK_ERK1_MAPK1_ST	Q5JQC9	AKAP4	P28482	MAPK1	S492	A493P	493	Missense	proximal	1	no	7.331	14.962	EPSD	COSMIC	8.102	Gain
CMGC_MAPK_ERK1_MAPK1_ST	Q5JQC9	AKAP4	P28482	MAPK1	S573	C570S	570	Missense	distal	-3	no	7.772	8.298	EPSD	COSMIC;GDSC	8.102	Gain
CMGC_MAPK_ERK1_MAPK1_ST	Q5JQC9	AKAP4	P28482	MAPK1	S808	S808G	808	Missense	central	0	yes	8.473	0.000	EPSD	COSMIC	8.102	Loss
CMGC_MAPK_ERK1_MAPK1_ST	Q5JQC9	AKAP4	P28482	MAPK1	S808	A811E	811	Missense	distal	3	no	8.473	8.386	EPSD	COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q5JQC9	AKAP4	P28482	MAPK1	S808	L804R	804	Missense	distal	-4	no	8.473	8.688	EPSD	COSMIC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P17861	XBP1	P28482	MAPK1	T14	D12V	12	Missense	proximal	-2	no	15.259	16.688	EPSD	COSMIC;GDSC;CCLE	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P17861	XBP1	P28482	MAPK1	S47	S47R	47	Missense	central	0	yes	14.397	0.000	EPSD	COSMIC	8.102	Loss
CMGC_MAPK_ERK1_MAPK1_ST	P17861	XBP1	P28482	MAPK1	S47	A51V	51	Missense	distal	4	no	14.397	14.391	EPSD	COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P17861	XBP1	P28482	MAPK1	S68	T65M	65	Missense	distal	-3	no	13.013	12.784	PhosphoSitePlus;EPSD	COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P17861	XBP1	P28482	MAPK1	S181	Q179R	179	Missense	proximal	-2	no	15.050	16.225	EPSD;PhosphoSitePlus	COSMIC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P17861	XBP1	P28482	MAPK1	S181	S187C	187	Missense	distal	6	no	15.050	14.182	EPSD;PhosphoSitePlus	COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q8IZP0	ABI1	P28482	MAPK1	S22	N25S	25	Missense	distal	3	no	9.403	9.481	EPSD	COSMIC;CCLE	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q8IZP0	ABI1	P28482	MAPK1	S183	G190E	190	Missense	distal	7	no	18.918	18.791	EPSD;PhosphoSitePlus	COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q8IZP0	ABI1	P28482	MAPK1	S183	G188R	188	Missense	distal	5	no	18.918	18.969	EPSD;PhosphoSitePlus	COSMIC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q8IZP0	ABI1	P28482	MAPK1	T196	G193R	193	Missense	distal	-3	no	14.788	14.957	EPSD	COSMIC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q8IZP0	ABI1	P28482	MAPK1	T196	G190E	190	Missense	distal	-6	no	14.788	14.842	EPSD	COSMIC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q8IZP0	ABI1	P28482	MAPK1	T196	N195S	195	Missense	proximal	-1	no	14.788	14.739	EPSD	COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q8IZP0	ABI1	P28482	MAPK1	S216	T215N	215	Missense	proximal	-1	no	13.107	13.155	EPSD;PhosphoSitePlus	COSMIC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q8IZP0	ABI1	P28482	MAPK1	S216	P217L	217	Missense	proximal	1	no	13.107	4.297	EPSD;PhosphoSitePlus	COSMIC	8.102	Loss
CMGC_MAPK_ERK1_MAPK1_ST	Q8IZP0	ABI1	P28482	MAPK1	S225	H224Y	224	Missense	proximal	-1	no	13.152	13.120	EPSD;PhosphoSitePlus	COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q8IZP0	ABI1	P28482	MAPK1	T238	S240I	240	Missense	proximal	2	no	10.742	10.599	EPSD	COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q8IZP0	ABI1	P28482	MAPK1	T238	S243G	243	Missense	distal	5	no	10.742	10.723	EPSD	COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q8IZP0	ABI1	P28482	MAPK1	T265	P266H	266	Missense	proximal	1	no	15.577	7.754	EPSD;PhosphoSitePlus	COSMIC	8.102	Loss
CMGC_MAPK_ERK1_MAPK1_ST	Q8IZP0	ABI1	P28482	MAPK1	T265	P268T	268	Missense	distal	3	no	15.577	15.639	EPSD;PhosphoSitePlus	COSMIC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q8IZP0	ABI1	P28482	MAPK1	S267	P266H	266	Missense	proximal	-1	no	13.872	13.830	EPSD;PhosphoSitePlus	COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q8IZP0	ABI1	P28482	MAPK1	S267	P268T	268	Missense	proximal	1	no	13.872	5.374	EPSD;PhosphoSitePlus	COSMIC	8.102	Loss
CMGC_MAPK_ERK1_MAPK1_ST	Q8IZP0	ABI1	P28482	MAPK1	T336	P337T	337	Missense	proximal	1	no	15.442	6.943	EPSD	COSMIC	8.102	Loss
CMGC_MAPK_ERK1_MAPK1_ST	Q8IZP0	ABI1	P28482	MAPK1	T336	S338C	338	Missense	proximal	2	no	15.442	15.210	EPSD	COSMIC;GDSC;CCLE	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q8IZP0	ABI1	P28482	MAPK1	T336	T336A	336	Missense	central	0	yes	15.442	0.000	EPSD	COSMIC	8.102	Loss
CMGC_MAPK_ERK1_MAPK1_ST	Q8IZP0	ABI1	P28482	MAPK1	S392	P399S	399	Missense	distal	7	no	12.998	13.009	EPSD;PhosphoSitePlus	COSMIC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q8IZP0	ABI1	P28482	MAPK1	S392	A390T	390	Missense	proximal	-2	no	12.998	13.445	EPSD;PhosphoSitePlus	COSMIC;GDSC;CCLE	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q8IZP0	ABI1	P28482	MAPK1	S392	P399T	399	Missense	distal	7	no	12.998	13.161	EPSD;PhosphoSitePlus	COSMIC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q8IZP0	ABI1	P28482	MAPK1	T394	P400L	400	Missense	distal	6	no	13.771	13.365	EPSD;PhosphoSitePlus	COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q8IZP0	ABI1	P28482	MAPK1	T394	P399S	399	Missense	distal	5	no	13.771	13.789	EPSD;PhosphoSitePlus	COSMIC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q8IZP0	ABI1	P28482	MAPK1	T394	A390T	390	Missense	distal	-4	no	13.771	13.751	EPSD;PhosphoSitePlus	COSMIC;GDSC;CCLE	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q8IZP0	ABI1	P28482	MAPK1	T394	P399T	399	Missense	distal	5	no	13.771	13.715	EPSD;PhosphoSitePlus	COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q8IZP0	ABI1	P28482	MAPK1	S410	D403N	403	Missense	distal	-7	no	14.946	14.947	PhosphoSitePlus;EPSD	COSMIC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q8IZP0	ABI1	P28482	MAPK1	S410	P412H	412	Missense	proximal	2	no	14.946	14.816	PhosphoSitePlus;EPSD	COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q8IZP0	ABI1	P28482	MAPK1	S410	P416T	416	Missense	distal	6	no	14.946	14.736	PhosphoSitePlus;EPSD	COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q8IZP0	ABI1	P28482	MAPK1	S410	P414S	414	Missense	distal	4	no	14.946	14.935	PhosphoSitePlus;EPSD	COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q8IZP0	ABI1	P28482	MAPK1	S410	P412L	412	Missense	proximal	2	no	14.946	14.799	PhosphoSitePlus;EPSD	COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q8IZP0	ABI1	P28482	MAPK1	S410	P411S	411	Missense	proximal	1	no	14.946	5.551	PhosphoSitePlus;EPSD	COSMIC	8.102	Loss
CMGC_MAPK_ERK1_MAPK1_ST	Q8IZP0	ABI1	P28482	MAPK1	S410	P417T	417	Missense	distal	7	no	14.946	15.109	PhosphoSitePlus;EPSD	COSMIC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q8IZP0	ABI1	P28482	MAPK1	S410	P412T	412	Missense	proximal	2	no	14.946	14.896	PhosphoSitePlus;EPSD	COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q8IZP0	ABI1	P28482	MAPK1	S410	P413H	413	Missense	distal	3	no	14.946	15.035	PhosphoSitePlus;EPSD	COSMIC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q8IZP0	ABI1	P28482	MAPK1	S502	G497V	497	Missense	distal	-5	no	9.705	9.733	EPSD	COSMIC;CCLE	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P35658	NUP214	P28482	MAPK1	S30	V25M	25	Missense	distal	-5	no	14.354	14.411	EPSD	COSMIC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P35658	NUP214	P28482	MAPK1	S201	C199F	199	Missense	proximal	-2	no	13.850	14.976	EPSD	COSMIC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P35658	NUP214	P28482	MAPK1	S268	T267M	267	Missense	proximal	-1	no	14.061	14.053	EPSD	COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P35658	NUP214	P28482	MAPK1	S268	A274V	274	Missense	distal	6	no	14.061	14.142	EPSD	COSMIC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P35658	NUP214	P28482	MAPK1	S268	E266K	266	Missense	proximal	-2	no	14.061	14.021	EPSD	COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P35658	NUP214	P28482	MAPK1	S268	D262Y	262	Missense	distal	-6	no	14.061	13.897	EPSD	COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P35658	NUP214	P28482	MAPK1	T416	S412F	412	Missense	distal	-4	no	13.103	12.842	EPSD	COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P35658	NUP214	P28482	MAPK1	S430	G424A	424	Missense	distal	-6	no	17.480	17.483	EPSD	COSMIC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P35658	NUP214	P28482	MAPK1	S430	P435S	435	Missense	distal	5	no	17.480	17.498	EPSD	COSMIC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P35658	NUP214	P28482	MAPK1	S430	P431S	431	Missense	proximal	1	no	17.480	8.085	EPSD	COSMIC;GDSC	8.102	Loss
CMGC_MAPK_ERK1_MAPK1_ST	P35658	NUP214	P28482	MAPK1	S430	R426Q	426	Missense	distal	-4	no	17.480	17.376	EPSD	COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P35658	NUP214	P28482	MAPK1	S430	T437I	437	Missense	distal	7	no	17.480	17.875	EPSD	COSMIC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P35658	NUP214	P28482	MAPK1	T434	P435S	435	Missense	proximal	1	no	12.901	3.506	EPSD	COSMIC	8.102	Loss
CMGC_MAPK_ERK1_MAPK1_ST	P35658	NUP214	P28482	MAPK1	T434	P431S	431	Missense	distal	-3	no	12.901	12.725	EPSD	COSMIC;GDSC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P35658	NUP214	P28482	MAPK1	T434	T437I	437	Missense	distal	3	no	12.901	12.967	EPSD	COSMIC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P35658	NUP214	P28482	MAPK1	T437	P435S	435	Missense	proximal	-2	no	14.442	11.608	EPSD	COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P35658	NUP214	P28482	MAPK1	T437	P431S	431	Missense	distal	-6	no	14.442	14.416	EPSD	COSMIC;GDSC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P35658	NUP214	P28482	MAPK1	T437	S440P	440	Missense	distal	3	no	14.442	14.373	EPSD	COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P35658	NUP214	P28482	MAPK1	T437	T437I	437	Missense	central	0	yes	14.442	0.000	EPSD	COSMIC	8.102	Loss
CMGC_MAPK_ERK1_MAPK1_ST	P35658	NUP214	P28482	MAPK1	T439	S440P	440	Missense	proximal	1	no	5.642	15.037	EPSD	COSMIC	8.102	Gain
CMGC_MAPK_ERK1_MAPK1_ST	P35658	NUP214	P28482	MAPK1	S462	A465V	465	Missense	distal	3	no	15.877	15.857	EPSD	COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P35658	NUP214	P28482	MAPK1	S462	P455L	455	Missense	distal	-7	no	15.877	15.865	EPSD	COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P35658	NUP214	P28482	MAPK1	S462	A456T	456	Missense	distal	-6	no	15.877	15.867	EPSD	COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P35658	NUP214	P28482	MAPK1	S462	T469P	469	Missense	distal	7	no	15.877	15.714	EPSD	COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P35658	NUP214	P28482	MAPK1	S483	T480A	480	Missense	distal	-3	no	8.551	8.393	EPSD	COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P35658	NUP214	P28482	MAPK1	S483	A478T	478	Missense	distal	-5	no	8.551	8.528	EPSD	COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P35658	NUP214	P28482	MAPK1	S501	P499S	499	Missense	proximal	-2	no	10.542	7.708	EPSD	COSMIC	8.102	Loss
CMGC_MAPK_ERK1_MAPK1_ST	P35658	NUP214	P28482	MAPK1	T519	T519P	519	Missense	central	0	yes	10.270	0.000	EPSD	COSMIC	8.102	Loss
CMGC_MAPK_ERK1_MAPK1_ST	P35658	NUP214	P28482	MAPK1	T519	S518G	518	Missense	proximal	-1	no	10.270	10.259	EPSD	COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P35658	NUP214	P28482	MAPK1	T519	G516D	516	Missense	distal	-3	no	10.270	10.330	EPSD	COSMIC;CCLE	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P35658	NUP214	P28482	MAPK1	T519	P524L	524	Missense	distal	5	no	10.270	10.057	EPSD	COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P35658	NUP214	P28482	MAPK1	T533	L530Q	530	Missense	distal	-3	no	13.509	13.596	EPSD	COSMIC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P35658	NUP214	P28482	MAPK1	T533	K527E	527	Missense	distal	-6	no	13.509	13.535	EPSD	COSMIC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P35658	NUP214	P28482	MAPK1	T533	P534S	534	Missense	proximal	1	no	13.509	4.115	EPSD	COSMIC	8.102	Loss
CMGC_MAPK_ERK1_MAPK1_ST	P35658	NUP214	P28482	MAPK1	T533	S537A	537	Missense	distal	4	no	13.509	13.416	EPSD	COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P35658	NUP214	P28482	MAPK1	T533	A531T	531	Missense	proximal	-2	no	13.509	13.957	EPSD	COSMIC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P35658	NUP214	P28482	MAPK1	T533	A531V	531	Missense	proximal	-2	no	13.509	14.783	EPSD	COSMIC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P35658	NUP214	P28482	MAPK1	S537	L530Q	530	Missense	distal	-7	no	13.011	13.026	EPSD	COSMIC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P35658	NUP214	P28482	MAPK1	S537	P534S	534	Missense	distal	-3	no	13.011	12.835	EPSD	COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P35658	NUP214	P28482	MAPK1	S537	S537A	537	Missense	central	0	yes	13.011	0.000	EPSD	COSMIC	8.102	Loss
CMGC_MAPK_ERK1_MAPK1_ST	P35658	NUP214	P28482	MAPK1	S537	A531T	531	Missense	distal	-6	no	13.011	13.001	EPSD	COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P35658	NUP214	P28482	MAPK1	S537	A531V	531	Missense	distal	-6	no	13.011	12.964	EPSD	COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P35658	NUP214	P28482	MAPK1	T560	V562M	562	Missense	proximal	2	no	12.574	12.436	EPSD	COSMIC;GDSC;CCLE	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P35658	NUP214	P28482	MAPK1	T560	E558K	558	Missense	proximal	-2	no	12.574	12.534	EPSD	COSMIC;GDSC;CCLE	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P35658	NUP214	P28482	MAPK1	T560	L557F	557	Missense	distal	-3	no	12.574	12.548	EPSD	COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P35658	NUP214	P28482	MAPK1	T560	P561T	561	Missense	proximal	1	no	12.574	4.075	EPSD	COSMIC	8.102	Loss
CMGC_MAPK_ERK1_MAPK1_ST	P35658	NUP214	P28482	MAPK1	T560	P561L	561	Missense	proximal	1	no	12.574	3.764	EPSD	COSMIC	8.102	Loss
CMGC_MAPK_ERK1_MAPK1_ST	P35658	NUP214	P28482	MAPK1	T598	P599L	599	Missense	proximal	1	no	14.059	5.249	EPSD	COSMIC	8.102	Loss
CMGC_MAPK_ERK1_MAPK1_ST	P35658	NUP214	P28482	MAPK1	T598	P599S	599	Missense	proximal	1	no	14.059	4.664	EPSD	COSMIC	8.102	Loss
CMGC_MAPK_ERK1_MAPK1_ST	P35658	NUP214	P28482	MAPK1	T598	A595V	595	Missense	distal	-3	no	14.059	14.119	EPSD	COSMIC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P35658	NUP214	P28482	MAPK1	T598	A595T	595	Missense	distal	-3	no	14.059	14.217	EPSD	COSMIC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P35658	NUP214	P28482	MAPK1	T598	S605Y	605	Missense	distal	7	no	14.059	14.577	EPSD	COSMIC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P35658	NUP214	P28482	MAPK1	S610	S610L	610	Missense	central	0	yes	16.311	0.000	EPSD	COSMIC;GDSC;CCLE	8.102	Loss
CMGC_MAPK_ERK1_MAPK1_ST	P35658	NUP214	P28482	MAPK1	S610	A606V	606	Missense	distal	-4	no	16.311	16.251	EPSD	COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P35658	NUP214	P28482	MAPK1	S610	P608L	608	Missense	proximal	-2	no	16.311	14.394	EPSD	COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P35658	NUP214	P28482	MAPK1	S610	A606T	606	Missense	distal	-4	no	16.311	16.291	EPSD	COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P35658	NUP214	P28482	MAPK1	S610	S605Y	605	Missense	distal	-5	no	16.311	16.442	EPSD	COSMIC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P35658	NUP214	P28482	MAPK1	S625	G622V	622	Missense	distal	-3	no	9.113	8.995	EPSD	COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P35658	NUP214	P28482	MAPK1	S625	S625F	625	Missense	central	0	yes	9.113	0.000	EPSD	COSMIC	8.102	Loss
CMGC_MAPK_ERK1_MAPK1_ST	P35658	NUP214	P28482	MAPK1	S625	S631L	631	Missense	distal	6	no	9.113	8.706	EPSD	COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P35658	NUP214	P28482	MAPK1	S625	A619T	619	Missense	distal	-6	no	9.113	9.103	EPSD	COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P35658	NUP214	P28482	MAPK1	T628	G622V	622	Missense	distal	-6	no	13.864	13.821	EPSD	COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P35658	NUP214	P28482	MAPK1	T628	S625F	625	Missense	distal	-3	no	13.864	13.632	EPSD	COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P35658	NUP214	P28482	MAPK1	T628	S631L	631	Missense	distal	3	no	13.864	13.885	EPSD	COSMIC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P35658	NUP214	P28482	MAPK1	T628	S631P	631	Missense	distal	3	no	13.864	13.795	EPSD	COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P35658	NUP214	P28482	MAPK1	S631	S636F	636	Missense	distal	5	no	8.602	8.405	EPSD	COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P35658	NUP214	P28482	MAPK1	S631	S625F	625	Missense	distal	-6	no	8.602	8.518	EPSD	COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P35658	NUP214	P28482	MAPK1	S631	S631L	631	Missense	central	0	yes	8.602	0.000	EPSD	COSMIC	8.102	Loss
CMGC_MAPK_ERK1_MAPK1_ST	P35658	NUP214	P28482	MAPK1	S631	S631P	631	Missense	central	0	yes	8.602	0.000	EPSD	COSMIC	8.102	Loss
CMGC_MAPK_ERK1_MAPK1_ST	P35658	NUP214	P28482	MAPK1	S635	S636F	636	Missense	proximal	1	no	6.113	8.939	EPSD	COSMIC	8.102	Gain
CMGC_MAPK_ERK1_MAPK1_ST	P35658	NUP214	P28482	MAPK1	S646	P647S	647	Missense	proximal	1	no	13.952	4.557	EPSD	COSMIC	8.102	Loss
CMGC_MAPK_ERK1_MAPK1_ST	P35658	NUP214	P28482	MAPK1	S646	L644S	644	Missense	proximal	-2	no	13.952	13.035	EPSD	COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P35658	NUP214	P28482	MAPK1	S646	S648L	648	Missense	proximal	2	no	13.952	13.832	EPSD	COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P35658	NUP214	P28482	MAPK1	S666	T670A	670	Missense	distal	4	no	15.014	15.033	EPSD	COSMIC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P35658	NUP214	P28482	MAPK1	S666	T670I	670	Missense	distal	4	no	15.014	14.961	EPSD	COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P35658	NUP214	P28482	MAPK1	T670	P672S	672	Missense	proximal	2	no	13.828	13.800	EPSD	COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P35658	NUP214	P28482	MAPK1	T670	T670A	670	Missense	central	0	yes	13.828	0.000	EPSD	COSMIC	8.102	Loss
CMGC_MAPK_ERK1_MAPK1_ST	P35658	NUP214	P28482	MAPK1	T670	A674T	674	Missense	distal	4	no	13.828	13.808	EPSD	COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P35658	NUP214	P28482	MAPK1	T670	T670I	670	Missense	central	0	yes	13.828	0.000	EPSD	COSMIC	8.102	Loss
CMGC_MAPK_ERK1_MAPK1_ST	P35658	NUP214	P28482	MAPK1	S678	P672S	672	Missense	distal	-6	no	16.723	16.697	EPSD	COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P35658	NUP214	P28482	MAPK1	S678	A674T	674	Missense	distal	-4	no	16.723	16.703	EPSD	COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P35658	NUP214	P28482	MAPK1	S678	K682N	682	Missense	distal	4	no	16.723	16.698	EPSD	COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P35658	NUP214	P28482	MAPK1	S940	P933L	933	Missense	distal	-7	no	13.297	13.285	EPSD	COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P35658	NUP214	P28482	MAPK1	S940	P941H	941	Missense	proximal	1	no	13.297	5.473	EPSD	COSMIC;GDSC;CCLE	8.102	Loss
CMGC_MAPK_ERK1_MAPK1_ST	P35658	NUP214	P28482	MAPK1	T956	R960T	960	Missense	distal	4	no	13.511	13.421	EPSD	COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P35658	NUP214	P28482	MAPK1	T1021	P1022L	1022	Missense	proximal	1	no	14.288	5.478	EPSD	COSMIC	8.102	Loss
CMGC_MAPK_ERK1_MAPK1_ST	P35658	NUP214	P28482	MAPK1	T1021	R1020H	1020	Missense	proximal	-1	no	14.288	14.265	EPSD	COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P35658	NUP214	P28482	MAPK1	T1021	V1018M	1018	Missense	distal	-3	no	14.288	14.158	EPSD	COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P35658	NUP214	P28482	MAPK1	S1081	V1075M	1075	Missense	distal	-6	no	12.235	12.237	EPSD	COSMIC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P35658	NUP214	P28482	MAPK1	S1081	T1074I	1074	Missense	distal	-7	no	12.235	12.220	EPSD	COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P35658	NUP214	P28482	MAPK1	T1134	G1140C	1140	Missense	distal	6	no	15.121	14.331	EPSD	COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P35658	NUP214	P28482	MAPK1	T1134	T1137I	1137	Missense	distal	3	no	15.121	15.187	EPSD	COSMIC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P35658	NUP214	P28482	MAPK1	T1134	P1132T	1132	Missense	proximal	-2	no	15.121	12.422	EPSD	COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P35658	NUP214	P28482	MAPK1	T1150	P1157Q	1157	Missense	distal	7	no	13.990	14.119	EPSD	COSMIC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P35658	NUP214	P28482	MAPK1	T1156	Q1162L	1162	Missense	distal	6	no	12.647	12.528	EPSD	COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P35658	NUP214	P28482	MAPK1	T1156	P1157Q	1157	Missense	proximal	1	no	12.647	4.153	EPSD	COSMIC	8.102	Loss
CMGC_MAPK_ERK1_MAPK1_ST	P35658	NUP214	P28482	MAPK1	T1156	V1158M	1158	Missense	proximal	2	no	12.647	12.510	EPSD	COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P35658	NUP214	P28482	MAPK1	T1178	G1182S	1182	Missense	distal	4	no	9.949	9.999	EPSD	COSMIC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P35658	NUP214	P28482	MAPK1	T1201	S1202P	1202	Missense	proximal	1	no	3.624	13.019	EPSD	COSMIC	8.102	Gain
CMGC_MAPK_ERK1_MAPK1_ST	P35658	NUP214	P28482	MAPK1	T1203	A1206T	1206	Missense	distal	3	no	13.541	13.524	EPSD	COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P35658	NUP214	P28482	MAPK1	T1203	V1200M	1200	Missense	distal	-3	no	13.541	13.410	EPSD	COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P35658	NUP214	P28482	MAPK1	T1203	S1202P	1202	Missense	proximal	-1	no	13.541	13.584	EPSD	COSMIC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P35658	NUP214	P28482	MAPK1	T1203	S1207F	1207	Missense	distal	4	no	13.541	13.363	EPSD	COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P35658	NUP214	P28482	MAPK1	T1203	S1205L	1205	Missense	proximal	2	no	13.541	13.421	EPSD	COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P35658	NUP214	P28482	MAPK1	S1215	K1212N	1212	Missense	distal	-3	no	8.721	8.818	EPSD	COSMIC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P35658	NUP214	P28482	MAPK1	S1217	K1212N	1212	Missense	distal	-5	no	13.544	13.567	EPSD	COSMIC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P35658	NUP214	P28482	MAPK1	T1231	A1238V	1238	Missense	distal	7	no	11.892	11.994	EPSD	COSMIC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P35658	NUP214	P28482	MAPK1	T1243	A1242S	1242	Missense	proximal	-1	no	13.230	13.224	EPSD	COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P35658	NUP214	P28482	MAPK1	T1243	G1241V	1241	Missense	proximal	-2	no	13.230	14.552	EPSD	COSMIC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P35658	NUP214	P28482	MAPK1	T1243	A1238V	1238	Missense	distal	-5	no	13.230	13.201	EPSD	COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P35658	NUP214	P28482	MAPK1	T1243	G1241W	1241	Missense	proximal	-2	no	13.230	13.683	EPSD	COSMIC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P35658	NUP214	P28482	MAPK1	T1243	T1246A	1246	Missense	distal	3	no	13.230	13.246	EPSD	COSMIC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P35658	NUP214	P28482	MAPK1	T1312	P1314L	1314	Missense	proximal	2	no	13.657	13.510	EPSD	COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P35658	NUP214	P28482	MAPK1	T1312	P1314S	1314	Missense	proximal	2	no	13.657	13.629	EPSD	COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P35658	NUP214	P28482	MAPK1	T1312	S1307T	1307	Missense	distal	-5	no	13.657	13.686	EPSD	COSMIC;GDSC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P35658	NUP214	P28482	MAPK1	T1312	T1312N	1312	Missense	central	0	yes	13.657	0.000	EPSD	COSMIC	8.102	Loss
CMGC_MAPK_ERK1_MAPK1_ST	P35658	NUP214	P28482	MAPK1	T1312	L1310F	1310	Missense	proximal	-2	no	13.657	12.934	EPSD	COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P35658	NUP214	P28482	MAPK1	T1312	S1315Y	1315	Missense	distal	3	no	13.657	13.715	EPSD	COSMIC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P35658	NUP214	P28482	MAPK1	T1568	E1566D	1566	Missense	proximal	-2	no	12.436	11.514	EPSD	COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P35658	NUP214	P28482	MAPK1	T1568	P1575L	1575	Missense	distal	7	no	12.436	12.735	EPSD	COSMIC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P35658	NUP214	P28482	MAPK1	T1568	S1564F	1564	Missense	distal	-4	no	12.436	12.175	EPSD	COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P35658	NUP214	P28482	MAPK1	T1568	G1573V	1573	Missense	distal	5	no	12.436	12.313	EPSD	COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P35658	NUP214	P28482	MAPK1	T1571	E1566D	1566	Missense	distal	-5	no	8.648	8.692	EPSD	COSMIC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P35658	NUP214	P28482	MAPK1	T1571	P1575L	1575	Missense	distal	4	no	8.648	8.527	EPSD	COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P35658	NUP214	P28482	MAPK1	T1571	S1564F	1564	Missense	distal	-7	no	8.648	8.627	EPSD	COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P35658	NUP214	P28482	MAPK1	T1571	G1573V	1573	Missense	proximal	2	no	8.648	8.576	EPSD	COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P35658	NUP214	P28482	MAPK1	T1571	R1578M	1578	Missense	distal	7	no	8.648	9.004	EPSD	COSMIC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P35658	NUP214	P28482	MAPK1	S1790	S1789C	1789	Missense	proximal	-1	no	13.834	13.755	EPSD	COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P35658	NUP214	P28482	MAPK1	S1790	T1793A	1793	Missense	distal	3	no	13.834	13.850	EPSD	COSMIC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P35658	NUP214	P28482	MAPK1	S1790	G1796V	1796	Missense	distal	6	no	13.834	13.696	EPSD	COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P35658	NUP214	P28482	MAPK1	S1809	Q1814H	1814	Missense	distal	5	no	12.938	12.931	PhosphoSitePlus;EPSD	COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P35658	NUP214	P28482	MAPK1	S1963	P1964L	1964	Missense	proximal	1	no	14.348	5.538	EPSD	COSMIC	8.102	Loss
CMGC_MAPK_ERK1_MAPK1_ST	P35658	NUP214	P28482	MAPK1	S1978	P1974L	1974	Missense	distal	-4	no	13.644	13.340	EPSD	COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P35658	NUP214	P28482	MAPK1	S1978	G1971C	1971	Missense	distal	-7	no	13.644	13.625	EPSD	COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P35658	NUP214	P28482	MAPK1	S1978	P1979H	1979	Missense	proximal	1	no	13.644	5.820	EPSD	COSMIC	8.102	Loss
CMGC_MAPK_ERK1_MAPK1_ST	P35658	NUP214	P28482	MAPK1	T1981	P1974L	1974	Missense	distal	-7	no	9.108	9.096	EPSD	COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P35658	NUP214	P28482	MAPK1	T1981	P1986T	1986	Missense	distal	5	no	9.108	9.052	EPSD	COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P35658	NUP214	P28482	MAPK1	T1981	P1979H	1979	Missense	proximal	-2	no	9.108	6.353	EPSD	COSMIC	8.102	Loss
CMGC_MAPK_ERK1_MAPK1_ST	P35658	NUP214	P28482	MAPK1	S1985	P1986T	1986	Missense	proximal	1	no	12.287	3.788	EPSD	COSMIC	8.102	Loss
CMGC_MAPK_ERK1_MAPK1_ST	P35658	NUP214	P28482	MAPK1	S1985	P1979H	1979	Missense	distal	-6	no	12.287	12.212	EPSD	COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P35658	NUP214	P28482	MAPK1	S2002	G2005S	2005	Missense	distal	3	no	13.857	13.842	EPSD	COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P35658	NUP214	P28482	MAPK1	S2002	G1995S	1995	Missense	distal	-7	no	13.857	13.871	EPSD	COSMIC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q15672	TWIST1	P28482	MAPK1	S8	S11L	11	Missense	distal	3	no	13.320	13.341	EPSD	COSMIC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q15672	TWIST1	P28482	MAPK1	S11	S11L	11	Missense	central	0	yes	16.599	0.000	EPSD	COSMIC	8.102	Loss
CMGC_MAPK_ERK1_MAPK1_ST	Q15672	TWIST1	P28482	MAPK1	S16	S11L	11	Missense	distal	-5	no	8.083	8.158	EPSD	COSMIC	8.102	Gain
CMGC_MAPK_ERK1_MAPK1_ST	Q15672	TWIST1	P28482	MAPK1	S68	R74S	74	Missense	distal	6	no	16.330	16.437	PhosphoSitePlus	COSMIC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q15672	TWIST1	P28482	MAPK1	S68	P66A	66	Missense	proximal	-2	no	16.330	13.183	PhosphoSitePlus	COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q15672	TWIST1	P28482	MAPK1	S99	E104K	104	Missense	distal	5	no	12.934	12.875	EPSD	COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q15672	TWIST1	P28482	MAPK1	S99	P100S	100	Missense	proximal	1	no	12.934	3.539	EPSD	COSMIC	8.102	Loss
CMGC_MAPK_ERK1_MAPK1_ST	Q15672	TWIST1	P28482	MAPK1	S102	P100S	100	Missense	proximal	-2	no	9.723	6.889	EPSD	COSMIC	8.102	Loss
CMGC_MAPK_ERK1_MAPK1_ST	Q15672	TWIST1	P28482	MAPK1	S102	T108M	108	Missense	distal	6	no	9.723	9.500	EPSD	COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q15796	SMAD2	P28482	MAPK1	T8	F7S	7	Missense	proximal	-1	no	15.387	15.433	EPSD	COSMIC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q15796	SMAD2	P28482	MAPK1	T8	V12L	12	Missense	distal	4	no	15.387	15.376	EPSD	COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q15796	SMAD2	P28482	MAPK1	T8	S2P	2	Missense	distal	-6	no	15.387	15.413	EPSD	COSMIC;GDSC;CCLE	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q15796	SMAD2	P28482	MAPK1	T8	S2L	2	Missense	distal	-6	no	15.387	15.321	EPSD	COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q15796	SMAD2	P28482	MAPK1	T8	S3F	3	Missense	distal	-5	no	15.387	15.475	EPSD	COSMIC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q15796	SMAD2	P28482	MAPK1	S21	A22V	22	Missense	proximal	1	no	8.307	6.397	EPSD	COSMIC	8.102	Loss
CMGC_MAPK_ERK1_MAPK1_ST	Q15796	SMAD2	P28482	MAPK1	S21	K20N	20	Missense	proximal	-1	no	8.307	8.300	EPSD	COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q15796	SMAD2	P28482	MAPK1	S21	G23D	23	Missense	proximal	2	no	8.307	8.273	EPSD	COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q15796	SMAD2	P28482	MAPK1	S21	S21L	21	Missense	central	0	yes	8.307	0.000	EPSD	COSMIC	8.102	Loss
CMGC_MAPK_ERK1_MAPK1_ST	Q15796	SMAD2	P28482	MAPK1	T172	Y165D	165	Missense	distal	-7	no	12.938	12.970	EPSD	COSMIC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q15796	SMAD2	P28482	MAPK1	T172	P177S	177	Missense	distal	5	no	12.938	12.956	EPSD	COSMIC;GDSC;CCLE	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q15796	SMAD2	P28482	MAPK1	T172	R169G	169	Missense	distal	-3	no	12.938	12.769	EPSD	COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q15796	SMAD2	P28482	MAPK1	T172	Y167C	167	Missense	distal	-5	no	12.938	13.010	EPSD	COSMIC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q15796	SMAD2	P28482	MAPK1	T172	H166Q	166	Missense	distal	-6	no	12.938	12.997	EPSD	COSMIC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q15796	SMAD2	P28482	MAPK1	T172	Y165F	165	Missense	distal	-7	no	12.938	12.949	EPSD	COSMIC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q15796	SMAD2	P28482	MAPK1	T220	T220M	220	Missense	central	0	yes	12.681	0.000	EPSD;PhosphoSitePlus	COSMIC;GDSC;CCLE	8.102	Loss
CMGC_MAPK_ERK1_MAPK1_ST	Q15796	SMAD2	P28482	MAPK1	T220	E219K	219	Missense	proximal	-1	no	12.681	12.709	EPSD;PhosphoSitePlus	COSMIC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q15796	SMAD2	P28482	MAPK1	T220	P218L	218	Missense	proximal	-2	no	12.681	10.764	EPSD;PhosphoSitePlus	COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q15796	SMAD2	P28482	MAPK1	T220	T220A	220	Missense	central	0	yes	12.681	0.000	EPSD;PhosphoSitePlus	COSMIC	8.102	Loss
CMGC_MAPK_ERK1_MAPK1_ST	Q15796	SMAD2	P28482	MAPK1	T220	P221S	221	Missense	proximal	1	no	12.681	3.286	EPSD;PhosphoSitePlus	COSMIC	8.102	Loss
CMGC_MAPK_ERK1_MAPK1_ST	Q15796	SMAD2	P28482	MAPK1	T220	P218S	218	Missense	proximal	-2	no	12.681	9.847	EPSD;PhosphoSitePlus	COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q15796	SMAD2	P28482	MAPK1	T220	Q213H	213	Missense	distal	-7	no	12.681	12.662	EPSD;PhosphoSitePlus	COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q15796	SMAD2	P28482	MAPK1	T220	P223S	223	Missense	distal	3	no	12.681	12.750	EPSD;PhosphoSitePlus	COSMIC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q15796	SMAD2	P28482	MAPK1	S245	D242E	242	Missense	distal	-3	no	15.166	15.114	EPSD;PhosphoSitePlus	COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q15796	SMAD2	P28482	MAPK1	S245	L249V	249	Missense	distal	4	no	15.166	15.176	EPSD;PhosphoSitePlus	COSMIC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q15796	SMAD2	P28482	MAPK1	S245	E248Q	248	Missense	distal	3	no	15.166	15.243	EPSD;PhosphoSitePlus	COSMIC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q15796	SMAD2	P28482	MAPK1	S245	S245C	245	Missense	central	0	yes	15.166	0.000	EPSD;PhosphoSitePlus	COSMIC	8.102	Loss
CMGC_MAPK_ERK1_MAPK1_ST	Q15796	SMAD2	P28482	MAPK1	S245	P246L	246	Missense	proximal	1	no	15.166	6.356	EPSD;PhosphoSitePlus	COSMIC	8.102	Loss
CMGC_MAPK_ERK1_MAPK1_ST	Q15796	SMAD2	P28482	MAPK1	S245	S240R	240	Missense	distal	-5	no	15.166	15.139	EPSD;PhosphoSitePlus	COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q15796	SMAD2	P28482	MAPK1	S250	S255F	255	Missense	distal	5	no	16.438	16.241	EPSD;PhosphoSitePlus	COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q15796	SMAD2	P28482	MAPK1	S250	L249V	249	Missense	proximal	-1	no	16.438	16.472	EPSD;PhosphoSitePlus	COSMIC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q15796	SMAD2	P28482	MAPK1	S250	E248Q	248	Missense	proximal	-2	no	16.438	15.824	EPSD;PhosphoSitePlus	COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q15796	SMAD2	P28482	MAPK1	S250	S245C	245	Missense	distal	-5	no	16.438	16.641	EPSD;PhosphoSitePlus	COSMIC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q15796	SMAD2	P28482	MAPK1	S250	P246L	246	Missense	distal	-4	no	16.438	16.134	EPSD;PhosphoSitePlus	COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q15796	SMAD2	P28482	MAPK1	S255	S255F	255	Missense	central	0	yes	16.866	0.000	PhosphoSitePlus;EPSD	COSMIC	8.102	Loss
CMGC_MAPK_ERK1_MAPK1_ST	Q15796	SMAD2	P28482	MAPK1	S255	L249V	249	Missense	distal	-6	no	16.866	16.872	PhosphoSitePlus;EPSD	COSMIC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q15796	SMAD2	P28482	MAPK1	S255	E248Q	248	Missense	distal	-7	no	16.866	16.864	PhosphoSitePlus;EPSD	COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q15796	SMAD2	P28482	MAPK1	T454	D450H	450	Missense	distal	-4	no	9.006	8.779	EPSD	COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q15796	SMAD2	P28482	MAPK1	T454	G457R	457	Missense	distal	3	no	9.006	8.969	EPSD	COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q15796	SMAD2	P28482	MAPK1	T454	P459H	459	Missense	distal	5	no	9.006	8.879	EPSD	COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q15796	SMAD2	P28482	MAPK1	S458	R462C	462	Missense	distal	4	no	12.677	12.418	EPSD	COSMIC;GDSC;CCLE	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q15796	SMAD2	P28482	MAPK1	S458	C463F	463	Missense	distal	5	no	12.677	12.880	EPSD	COSMIC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q15796	SMAD2	P28482	MAPK1	S458	G457R	457	Missense	proximal	-1	no	12.677	12.712	EPSD	COSMIC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q15796	SMAD2	P28482	MAPK1	S458	S465I	465	Missense	distal	7	no	12.677	13.225	EPSD	COSMIC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q15796	SMAD2	P28482	MAPK1	S458	C463Y	463	Missense	distal	5	no	12.677	12.788	EPSD	COSMIC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q15796	SMAD2	P28482	MAPK1	S458	S465N	465	Missense	distal	7	no	12.677	12.660	EPSD	COSMIC;GDSC;CCLE	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q15796	SMAD2	P28482	MAPK1	S458	P459H	459	Missense	proximal	1	no	12.677	4.853	EPSD	COSMIC	8.102	Loss
CMGC_MAPK_ERK1_MAPK1_ST	Q15796	SMAD2	P28482	MAPK1	S458	S465R	465	Missense	distal	7	no	12.677	12.681	EPSD	COSMIC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q15796	SMAD2	P28482	MAPK1	S458	S464L	464	Missense	distal	6	no	12.677	12.271	EPSD	COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q15796	SMAD2	P28482	MAPK1	S464	P459H	459	Missense	distal	-5	no	7.993	8.117	EPSD	COSMIC	8.102	Gain
CMGC_MAPK_ERK1_MAPK1_ST	P01100	FOS	P28482	MAPK1	S133	G127S	127	Missense	distal	-6	no	13.006	13.023	EPSD	COSMIC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P01100	FOS	P28482	MAPK1	S133	E137K	137	Missense	distal	4	no	13.006	13.021	EPSD	COSMIC;GDSC;CCLE	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P01100	FOS	P28482	MAPK1	T232	A231V	231	Missense	proximal	-1	no	16.008	16.019	PhosphoSitePlus	COSMIC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P01100	FOS	P28482	MAPK1	T325	V327A	327	Missense	proximal	2	no	13.838	13.762	EPSD	COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P01100	FOS	P28482	MAPK1	T331	V327A	327	Missense	distal	-4	no	15.184	15.245	EPSD	COSMIC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P01100	FOS	P28482	MAPK1	S362	S364I	364	Missense	proximal	2	no	10.992	10.849	EPSD	COSMIC;GDSC;CCLE	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P01100	FOS	P28482	MAPK1	S369	S371T	371	Missense	proximal	2	no	11.330	11.307	EPSD	COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P01100	FOS	P28482	MAPK1	S369	S364I	364	Missense	distal	-5	no	11.330	11.465	EPSD	COSMIC;GDSC;CCLE	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P01100	FOS	P28482	MAPK1	S371	S364I	364	Missense	distal	-7	no	8.188	8.161	EPSD	COSMIC;GDSC;CCLE	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P01100	FOS	P28482	MAPK1	S373	S371T	371	Missense	proximal	-2	no	9.180	9.314	EPSD	COSMIC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P01100	FOS	P28482	MAPK1	S373	A379V	379	Missense	distal	6	no	9.180	9.261	EPSD	COSMIC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P01100	FOS	P28482	MAPK1	S374	S371T	371	Missense	distal	-3	no	17.547	17.514	EPSD	COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P01100	FOS	P28482	MAPK1	S374	A379V	379	Missense	distal	5	no	17.547	17.564	EPSD	COSMIC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P01100	FOS	P28482	MAPK1	T376	S371T	371	Missense	distal	-5	no	8.102	8.130	EPSD	COSMIC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P01100	FOS	P28482	MAPK1	T376	A379V	379	Missense	distal	3	no	8.102	8.081	EPSD	COSMIC	8.102	Loss
CMGC_MAPK_ERK1_MAPK1_ST	Q14674	ESPL1	P28482	MAPK1	S244	L249P	249	Missense	distal	5	no	15.686	15.899	EPSD	COSMIC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q14674	ESPL1	P28482	MAPK1	S244	P245L	245	Missense	proximal	1	no	15.686	6.876	EPSD	COSMIC	8.102	Loss
CMGC_MAPK_ERK1_MAPK1_ST	Q14674	ESPL1	P28482	MAPK1	T1210	S1213T	1213	Missense	distal	3	no	14.034	14.027	EPSD	COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q14674	ESPL1	P28482	MAPK1	T1210	L1214F	1214	Missense	distal	4	no	14.034	13.966	EPSD	COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q14674	ESPL1	P28482	MAPK1	T1210	S1213F	1213	Missense	distal	3	no	14.034	14.097	EPSD	COSMIC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q14674	ESPL1	P28482	MAPK1	S1325	N1331S	1331	Missense	distal	6	no	8.033	8.129	EPSD	COSMIC	8.102	Gain
CMGC_MAPK_ERK1_MAPK1_ST	Q14674	ESPL1	P28482	MAPK1	T1346	R1352W	1352	Missense	distal	6	no	16.955	16.032	EPSD	COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q14674	ESPL1	P28482	MAPK1	T1346	D1351E	1351	Missense	distal	5	no	16.955	16.886	EPSD	COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q14674	ESPL1	P28482	MAPK1	T1346	P1344L	1344	Missense	proximal	-2	no	16.955	15.038	EPSD	COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q14674	ESPL1	P28482	MAPK1	S1406	L1411M	1411	Missense	distal	5	no	8.549	8.576	EPSD	COSMIC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q14674	ESPL1	P28482	MAPK1	S1444	P1446R	1446	Missense	proximal	2	no	8.363	8.476	EPSD	COSMIC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q14674	ESPL1	P28482	MAPK1	S1444	G1450A	1450	Missense	distal	6	no	8.363	8.144	EPSD	COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q14674	ESPL1	P28482	MAPK1	S1444	V1439M	1439	Missense	distal	-5	no	8.363	8.419	EPSD	COSMIC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q14674	ESPL1	P28482	MAPK1	S1444	A1445V	1445	Missense	proximal	1	no	8.363	6.453	EPSD	COSMIC	8.102	Loss
CMGC_MAPK_ERK1_MAPK1_ST	Q14674	ESPL1	P28482	MAPK1	S1501	T1494S	1494	Missense	distal	-7	no	8.514	8.526	EPSD	COSMIC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q14674	ESPL1	P28482	MAPK1	T1519	P1520L	1520	Missense	proximal	1	no	13.316	4.506	EPSD	COSMIC	8.102	Loss
CMGC_MAPK_ERK1_MAPK1_ST	Q14674	ESPL1	P28482	MAPK1	T1519	A1521T	1521	Missense	proximal	2	no	13.316	13.395	EPSD	COSMIC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q14674	ESPL1	P28482	MAPK1	S1545	K1540E	1540	Missense	distal	-5	no	12.245	12.268	EPSD	COSMIC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q14674	ESPL1	P28482	MAPK1	S1678	R1675H	1675	Missense	distal	-3	no	9.465	9.135	EPSD	COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q14674	ESPL1	P28482	MAPK1	S1678	R1675C	1675	Missense	distal	-3	no	9.465	8.781	EPSD	COSMIC;GDSC;CCLE	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q14674	ESPL1	P28482	MAPK1	S2118	G2114S	2114	Missense	distal	-4	no	8.539	8.805	EPSD	COSMIC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q14674	ESPL1	P28482	MAPK1	S2118	V2117A	2117	Missense	proximal	-1	no	8.539	8.528	EPSD	COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q14674	ESPL1	P28482	MAPK1	S2118	S2118F	2118	Missense	central	0	yes	8.539	0.000	EPSD	COSMIC	8.102	Loss
CMGC_MAPK_ERK1_MAPK1_ST	P19878	NCF2	P28482	MAPK1	S213	Q211R	211	Missense	proximal	-2	no	7.250	8.425	EPSD	COSMIC;GDSC;CCLE	8.102	Gain
CMGC_MAPK_ERK1_MAPK1_ST	P19878	NCF2	P28482	MAPK1	T233	P231R	231	Missense	proximal	-2	no	16.494	14.676	PhosphoSitePlus	COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P19878	NCF2	P28482	MAPK1	S312	D316V	316	Missense	distal	4	no	14.245	14.243	EPSD	COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P19878	NCF2	P28482	MAPK1	S332	E339D	339	Missense	distal	7	no	14.060	14.115	EPSD	COSMIC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P52945	PDX1	P28482	MAPK1	S31	P33L	33	Missense	proximal	2	no	11.583	11.435	EPSD	COSMIC;CCLE	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P52945	PDX1	P28482	MAPK1	S31	P33T	33	Missense	proximal	2	no	11.583	11.532	EPSD	COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P52945	PDX1	P28482	MAPK1	S31	P33H	33	Missense	proximal	2	no	11.583	11.453	EPSD	COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P52945	PDX1	P28482	MAPK1	S266	S266R	266	Missense	central	0	yes	9.485	0.000	EPSD	COSMIC;CCLE	8.102	Loss
CMGC_MAPK_ERK1_MAPK1_ST	P52945	PDX1	P28482	MAPK1	S268	S266R	266	Missense	proximal	-2	no	15.238	16.253	EPSD	COSMIC;CCLE	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P28562	DUSP1	P28482	MAPK1	T141	S146T	146	Missense	distal	5	no	10.564	10.490	EPSD	COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P28562	DUSP1	P28482	MAPK1	T141	S140L	140	Missense	proximal	-1	no	10.564	10.547	EPSD	COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P28562	DUSP1	P28482	MAPK1	S296	M302V	302	Missense	distal	6	no	13.957	14.176	EPSD;PhosphoSitePlus	COSMIC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P28562	DUSP1	P28482	MAPK1	S323	M326T	326	Missense	distal	3	no	14.078	14.055	PhosphoSitePlus;EPSD	COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P28562	DUSP1	P28482	MAPK1	S323	A327T	327	Missense	distal	4	no	14.078	14.058	PhosphoSitePlus;EPSD	COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P28562	DUSP1	P28482	MAPK1	S323	A319V	319	Missense	distal	-4	no	14.078	14.017	PhosphoSitePlus;EPSD	COSMIC;GDSC;CCLE	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P28562	DUSP1	P28482	MAPK1	S359	S355R	355	Missense	distal	-4	no	16.428	16.422	EPSD	COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P28562	DUSP1	P28482	MAPK1	S359	P360L	360	Missense	proximal	1	no	16.428	7.618	EPSD	COSMIC	8.102	Loss
CMGC_MAPK_ERK1_MAPK1_ST	P28562	DUSP1	P28482	MAPK1	S364	P360L	360	Missense	distal	-4	no	16.160	15.855	EPSD	COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q15648	MED1	P28482	MAPK1	S18	M16I	16	Missense	proximal	-2	no	6.825	8.945	EPSD	COSMIC	8.102	Gain
CMGC_MAPK_ERK1_MAPK1_ST	Q15648	MED1	P28482	MAPK1	T212	L211R	211	Missense	proximal	-1	no	13.734	13.774	EPSD	COSMIC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q15648	MED1	P28482	MAPK1	S238	N245S	245	Missense	distal	7	no	15.156	15.173	EPSD	COSMIC;GDSC;CCLE	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q15648	MED1	P28482	MAPK1	S434	G436V	436	Missense	proximal	2	no	12.254	12.182	EPSD	COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q15648	MED1	P28482	MAPK1	T522	D521N	521	Missense	proximal	-1	no	12.164	12.225	EPSD	COSMIC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q15648	MED1	P28482	MAPK1	S545	P542Q	542	Missense	distal	-3	no	12.578	12.281	EPSD	COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q15648	MED1	P28482	MAPK1	T562	T564I	564	Missense	proximal	2	no	13.604	13.484	EPSD	COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q15648	MED1	P28482	MAPK1	T562	P568Q	568	Missense	distal	6	no	13.604	13.317	EPSD	COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q15648	MED1	P28482	MAPK1	T562	P563T	563	Missense	proximal	1	no	13.604	5.106	EPSD	COSMIC	8.102	Loss
CMGC_MAPK_ERK1_MAPK1_ST	Q15648	MED1	P28482	MAPK1	S621	T623P	623	Missense	proximal	2	no	12.139	12.189	EPSD	COSMIC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q15648	MED1	P28482	MAPK1	S621	G614E	614	Missense	distal	-7	no	12.139	12.162	EPSD	COSMIC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q15648	MED1	P28482	MAPK1	T623	T623P	623	Missense	central	0	yes	14.078	0.000	EPSD	COSMIC	8.102	Loss
CMGC_MAPK_ERK1_MAPK1_ST	Q15648	MED1	P28482	MAPK1	T628	T623P	623	Missense	distal	-5	no	13.597	13.494	EPSD	COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q15648	MED1	P28482	MAPK1	S675	S673F	673	Missense	proximal	-2	no	13.798	13.992	EPSD	COSMIC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q15648	MED1	P28482	MAPK1	T735	H737Y	737	Missense	proximal	2	no	14.047	13.981	EPSD	COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q15648	MED1	P28482	MAPK1	T739	H737Y	737	Missense	proximal	-2	no	11.873	12.510	EPSD	COSMIC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q15648	MED1	P28482	MAPK1	T805	D798N	798	Missense	distal	-7	no	14.897	14.898	EPSD	COSMIC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q15648	MED1	P28482	MAPK1	T805	S810C	810	Missense	distal	5	no	14.897	14.497	EPSD	COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q15648	MED1	P28482	MAPK1	S848	L841V	841	Missense	distal	-7	no	13.014	13.007	EPSD	COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q15648	MED1	P28482	MAPK1	S848	L841F	841	Missense	distal	-7	no	13.014	13.001	EPSD	COSMIC;GDSC;CCLE	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q15648	MED1	P28482	MAPK1	T998	G993E	993	Missense	distal	-5	no	12.462	12.419	EPSD	COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q15648	MED1	P28482	MAPK1	T998	T998I	998	Missense	central	0	yes	12.462	0.000	EPSD	COSMIC	8.102	Loss
CMGC_MAPK_ERK1_MAPK1_ST	Q15648	MED1	P28482	MAPK1	T998	S1000F	1000	Missense	proximal	2	no	12.462	12.330	EPSD	COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q15648	MED1	P28482	MAPK1	S1021	P1022Q	1022	Missense	proximal	1	no	12.058	3.565	EPSD	COSMIC	8.102	Loss
CMGC_MAPK_ERK1_MAPK1_ST	Q15648	MED1	P28482	MAPK1	T1035	S1042L	1042	Missense	distal	7	no	7.993	8.281	EPSD	COSMIC	8.102	Gain
CMGC_MAPK_ERK1_MAPK1_ST	Q15648	MED1	P28482	MAPK1	S1036	S1042L	1042	Missense	distal	6	no	9.180	8.773	EPSD	COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q15648	MED1	P28482	MAPK1	S1042	G1044C	1044	Missense	proximal	2	no	13.323	13.045	EPSD	COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q15648	MED1	P28482	MAPK1	S1042	S1042L	1042	Missense	central	0	yes	13.323	0.000	EPSD	COSMIC	8.102	Loss
CMGC_MAPK_ERK1_MAPK1_ST	Q15648	MED1	P28482	MAPK1	S1045	G1044C	1044	Missense	proximal	-1	no	10.040	9.972	EPSD	COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q15648	MED1	P28482	MAPK1	S1045	P1052F	1052	Missense	distal	7	no	10.040	10.398	EPSD	COSMIC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q15648	MED1	P28482	MAPK1	S1045	P1052S	1052	Missense	distal	7	no	10.040	10.051	EPSD	COSMIC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q15648	MED1	P28482	MAPK1	S1045	S1042L	1042	Missense	distal	-3	no	10.040	9.832	EPSD	COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q15648	MED1	P28482	MAPK1	T1051	G1044C	1044	Missense	distal	-7	no	10.652	10.633	EPSD	COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q15648	MED1	P28482	MAPK1	T1051	P1052F	1052	Missense	proximal	1	no	10.652	4.083	EPSD	COSMIC	8.102	Loss
CMGC_MAPK_ERK1_MAPK1_ST	Q15648	MED1	P28482	MAPK1	T1051	P1052S	1052	Missense	proximal	1	no	10.652	1.257	EPSD	COSMIC	8.102	Loss
CMGC_MAPK_ERK1_MAPK1_ST	Q15648	MED1	P28482	MAPK1	T1057	P1052F	1052	Missense	distal	-5	no	13.270	13.433	EPSD	COSMIC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q15648	MED1	P28482	MAPK1	T1057	P1052S	1052	Missense	distal	-5	no	13.270	13.344	EPSD	COSMIC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q15648	MED1	P28482	MAPK1	S1156	P1157A	1157	Missense	proximal	1	no	14.765	7.134	EPSD	COSMIC	8.102	Loss
CMGC_MAPK_ERK1_MAPK1_ST	Q15648	MED1	P28482	MAPK1	S1207	G1214E	1214	Missense	distal	7	no	13.792	13.664	EPSD	COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q15648	MED1	P28482	MAPK1	T1215	G1214E	1214	Missense	proximal	-1	no	15.062	15.101	EPSD	COSMIC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q15648	MED1	P28482	MAPK1	T1215	P1217L	1217	Missense	proximal	2	no	15.062	14.914	EPSD	COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q15648	MED1	P28482	MAPK1	S1223	P1217L	1217	Missense	distal	-6	no	13.462	13.370	EPSD	COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q15648	MED1	P28482	MAPK1	S1223	G1228D	1228	Missense	distal	5	no	13.462	13.507	EPSD	COSMIC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q15648	MED1	P28482	MAPK1	T1259	P1260S	1260	Missense	proximal	1	no	12.401	3.006	EPSD	COSMIC	8.102	Loss
CMGC_MAPK_ERK1_MAPK1_ST	Q15648	MED1	P28482	MAPK1	S1294	S1290Y	1290	Missense	distal	-4	no	14.110	13.521	EPSD	COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q15648	MED1	P28482	MAPK1	T1440	R1445C	1445	Missense	distal	5	no	12.233	11.802	EPSD	COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q15648	MED1	P28482	MAPK1	S1447	R1445C	1445	Missense	proximal	-2	no	13.513	11.565	EPSD	COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q15648	MED1	P28482	MAPK1	S1453	P1458S	1458	Missense	distal	5	no	14.493	14.511	EPSD	COSMIC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q15648	MED1	P28482	MAPK1	T1457	P1458S	1458	Missense	proximal	1	no	14.347	4.952	PhosphoSitePlus;EPSD	COSMIC	8.102	Loss
CMGC_MAPK_ERK1_MAPK1_ST	Q15648	MED1	P28482	MAPK1	S1479	E1473D	1473	Missense	distal	-6	no	13.366	13.378	EPSD	COSMIC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q15648	MED1	P28482	MAPK1	S1479	S1479N	1479	Missense	central	0	yes	13.366	0.000	EPSD	COSMIC	8.102	Loss
CMGC_MAPK_ERK1_MAPK1_ST	Q15648	MED1	P28482	MAPK1	S1525	H1526Y	1526	Missense	proximal	1	no	7.464	8.279	EPSD	COSMIC	8.102	Gain
CMGC_MAPK_ERK1_MAPK1_ST	Q15648	MED1	P28482	MAPK1	S1532	S1525F	1525	Missense	distal	-7	no	9.948	9.928	EPSD	COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q15648	MED1	P28482	MAPK1	S1532	H1526Y	1526	Missense	distal	-6	no	9.948	9.883	EPSD	COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q15648	MED1	P28482	MAPK1	S1558	P1562S	1562	Missense	distal	4	no	8.659	8.648	EPSD	COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q15648	MED1	P28482	MAPK1	S1561	P1562S	1562	Missense	proximal	1	no	15.612	6.217	EPSD	COSMIC	8.102	Loss
CMGC_MAPK_ERK1_MAPK1_ST	P19525	EIF2AK2	P28482	MAPK1	T529	S530Y	530	Missense	proximal	1	no	8.525	10.911	EPSD	COSMIC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P19525	EIF2AK2	P28482	MAPK1	T535	K540M	540	Missense	distal	5	no	8.639	8.537	EPSD	COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P19525	EIF2AK2	P28482	MAPK1	T535	S530Y	530	Missense	distal	-5	no	8.639	8.770	EPSD	COSMIC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P19525	EIF2AK2	P28482	MAPK1	S542	R548Q	548	Missense	distal	6	no	14.844	14.663	EPSD	COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P19525	EIF2AK2	P28482	MAPK1	S542	K540M	540	Missense	proximal	-2	no	14.844	13.249	EPSD	COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q92974	ARHGEF2	P28482	MAPK1	S127	D128Y	128	Missense	proximal	1	no	6.728	8.415	EPSD	COSMIC	8.102	Gain
CMGC_MAPK_ERK1_MAPK1_ST	Q92974	ARHGEF2	P28482	MAPK1	S163	R168L	168	Missense	distal	5	no	15.493	15.230	EPSD	COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q92974	ARHGEF2	P28482	MAPK1	S163	D161N	161	Missense	proximal	-2	no	15.493	15.975	EPSD	COSMIC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q92974	ARHGEF2	P28482	MAPK1	S163	P164L	164	Missense	proximal	1	no	15.493	6.683	EPSD	COSMIC	8.102	Loss
CMGC_MAPK_ERK1_MAPK1_ST	Q92974	ARHGEF2	P28482	MAPK1	T455	T455K	455	Missense	central	0	yes	11.810	0.000	EPSD	COSMIC	8.102	Loss
CMGC_MAPK_ERK1_MAPK1_ST	Q92974	ARHGEF2	P28482	MAPK1	T455	M449I	449	Missense	distal	-6	no	11.810	11.767	EPSD	COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q92974	ARHGEF2	P28482	MAPK1	S648	R642C	642	Missense	distal	-6	no	16.786	16.611	EPSD	COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q92974	ARHGEF2	P28482	MAPK1	S648	S645F	645	Missense	distal	-3	no	16.786	16.554	EPSD	COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q92974	ARHGEF2	P28482	MAPK1	T679	L685V	685	Missense	distal	6	no	13.335	13.526	PhosphoSitePlus	COSMIC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q92974	ARHGEF2	P28482	MAPK1	S696	D690H	690	Missense	distal	-6	no	15.514	15.416	EPSD	COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q92974	ARHGEF2	P28482	MAPK1	S696	G703A	703	Missense	distal	7	no	15.514	15.626	EPSD	COSMIC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q92974	ARHGEF2	P28482	MAPK1	S733	L731V	731	Missense	proximal	-2	no	15.414	15.459	EPSD	COSMIC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q92974	ARHGEF2	P28482	MAPK1	S733	P734Q	734	Missense	proximal	1	no	15.414	6.921	EPSD	COSMIC	8.102	Loss
CMGC_MAPK_ERK1_MAPK1_ST	Q92974	ARHGEF2	P28482	MAPK1	S733	S733L	733	Missense	central	0	yes	15.414	0.000	EPSD	COSMIC	8.102	Loss
CMGC_MAPK_ERK1_MAPK1_ST	Q92974	ARHGEF2	P28482	MAPK1	S886	L887F	887	Missense	proximal	1	no	7.276	9.516	EPSD	COSMIC	8.102	Gain
CMGC_MAPK_ERK1_MAPK1_ST	Q92974	ARHGEF2	P28482	MAPK1	S932	P933S	933	Missense	proximal	1	no	13.424	4.029	EPSD	COSMIC	8.102	Loss
CMGC_MAPK_ERK1_MAPK1_ST	Q92974	ARHGEF2	P28482	MAPK1	S932	S932N	932	Missense	central	0	yes	13.424	0.000	EPSD	COSMIC	8.102	Loss
CMGC_MAPK_ERK1_MAPK1_ST	Q92974	ARHGEF2	P28482	MAPK1	S932	G931V	931	Missense	proximal	-1	no	13.424	13.452	EPSD	COSMIC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q92974	ARHGEF2	P28482	MAPK1	S932	R927S	927	Missense	distal	-5	no	13.424	13.451	EPSD	COSMIC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q92974	ARHGEF2	P28482	MAPK1	S932	E926Q	926	Missense	distal	-6	no	13.424	13.398	EPSD	COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q92974	ARHGEF2	P28482	MAPK1	S956	S952R	952	Missense	distal	-4	no	13.951	13.946	EPSD	COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q92974	ARHGEF2	P28482	MAPK1	S956	G951E	951	Missense	distal	-5	no	13.951	13.909	EPSD	COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q92974	ARHGEF2	P28482	MAPK1	S956	S952T	952	Missense	distal	-4	no	13.951	13.722	EPSD	COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q92974	ARHGEF2	P28482	MAPK1	S956	L955V	955	Missense	proximal	-1	no	13.951	13.985	EPSD	COSMIC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q92974	ARHGEF2	P28482	MAPK1	S960	L955V	955	Missense	distal	-5	no	17.909	17.856	EPSD	COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P37802	TAGLN2	P28482	MAPK1	S11	R12W	12	Missense	proximal	1	no	6.238	8.516	EPSD	COSMIC	8.102	Gain
CMGC_MAPK_ERK1_MAPK1_ST	P37802	TAGLN2	P28482	MAPK1	T190	G191F	191	Missense	proximal	1	no	4.630	8.126	EPSD	COSMIC	8.102	Gain
CMGC_MAPK_ERK1_MAPK1_ST	O94811	TPPP	P28482	MAPK1	S45	S49G	49	Missense	distal	4	no	13.039	12.990	EPSD	COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	O94811	TPPP	P28482	MAPK1	S160	R165M	165	Missense	distal	5	no	12.599	12.363	PhosphoSitePlus;EPSD	COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	O75582	RPS6KA5	P28482	MAPK1	S15	G10A	10	Missense	distal	-5	no	8.098	8.155	EPSD	COSMIC	8.102	Gain
CMGC_MAPK_ERK1_MAPK1_ST	O75582	RPS6KA5	P28482	MAPK1	S253	G251R	251	Missense	proximal	-2	no	12.735	14.111	EPSD	COSMIC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	O75582	RPS6KA5	P28482	MAPK1	S253	E260K	260	Missense	distal	7	no	12.735	12.743	EPSD	COSMIC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	O75582	RPS6KA5	P28482	MAPK1	S360	A362T	362	Missense	proximal	2	no	14.625	14.704	PhosphoSitePlus;EPSD	COSMIC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	O75582	RPS6KA5	P28482	MAPK1	S360	P357S	357	Missense	distal	-3	no	14.625	14.449	PhosphoSitePlus;EPSD	COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	O75582	RPS6KA5	P28482	MAPK1	S360	E354K	354	Missense	distal	-6	no	14.625	14.599	PhosphoSitePlus;EPSD	COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	O75582	RPS6KA5	P28482	MAPK1	S367	A362T	362	Missense	distal	-5	no	8.170	8.148	EPSD	COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	O75582	RPS6KA5	P28482	MAPK1	T581	P582L	582	Missense	proximal	1	no	16.095	7.285	EPSD;PhosphoSitePlus	COSMIC	8.102	Loss
CMGC_MAPK_ERK1_MAPK1_ST	O75582	RPS6KA5	P28482	MAPK1	T581	P578H	578	Missense	distal	-3	no	16.095	15.745	EPSD;PhosphoSitePlus	COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	O75582	RPS6KA5	P28482	MAPK1	T581	P578S	578	Missense	distal	-3	no	16.095	15.918	EPSD;PhosphoSitePlus	COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	O75582	RPS6KA5	P28482	MAPK1	T700	M699T	699	Missense	proximal	-1	no	14.834	14.842	EPSD	COSMIC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	O75582	RPS6KA5	P28482	MAPK1	S768	S766P	766	Missense	proximal	-2	no	6.101	8.935	EPSD	COSMIC	8.102	Gain
CMGC_MAPK_ERK1_MAPK1_ST	O75582	RPS6KA5	P28482	MAPK1	T793	D787N	787	Missense	distal	-6	no	9.441	9.395	EPSD	COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P29590	PML	P28482	MAPK1	T28	P26S	26	Missense	proximal	-2	no	18.769	15.935	PhosphoSitePlus;EPSD	COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P29590	PML	P28482	MAPK1	S38	R44Q	44	Missense	distal	6	no	15.024	14.843	EPSD;PhosphoSitePlus	COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P29590	PML	P28482	MAPK1	S40	R44Q	44	Missense	distal	4	no	13.758	13.683	EPSD;PhosphoSitePlus	COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P29590	PML	P28482	MAPK1	T196	T198M	198	Missense	proximal	2	no	14.026	13.886	EPSD	COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P29590	PML	P28482	MAPK1	T196	N193S	193	Missense	distal	-3	no	14.026	14.011	EPSD	COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P29590	PML	P28482	MAPK1	T482	Q483P	483	Missense	proximal	1	no	4.740	13.234	EPSD	COSMIC	8.102	Gain
CMGC_MAPK_ERK1_MAPK1_ST	P29590	PML	P28482	MAPK1	S505	P506L	506	Missense	proximal	1	no	13.675	4.865	EPSD	COSMIC	8.102	Loss
CMGC_MAPK_ERK1_MAPK1_ST	P29590	PML	P28482	MAPK1	T513	S514P	514	Missense	proximal	1	no	8.109	17.504	EPSD	COSMIC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P29590	PML	P28482	MAPK1	T513	P506L	506	Missense	distal	-7	no	8.109	8.097	EPSD	COSMIC	8.102	Loss
CMGC_MAPK_ERK1_MAPK1_ST	P29590	PML	P28482	MAPK1	S518	S514P	514	Missense	distal	-4	no	14.880	14.964	EPSD	COSMIC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P29590	PML	P28482	MAPK1	S561	S562P	562	Missense	proximal	1	no	3.754	13.149	EPSD	COSMIC	8.102	Gain
CMGC_MAPK_ERK1_MAPK1_ST	P29590	PML	P28482	MAPK1	T592	V595L	595	Missense	distal	3	no	8.676	8.709	EPSD	COSMIC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P29590	PML	P28482	MAPK1	T867	G871D	871	Missense	distal	4	no	17.434	17.386	EPSD	COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P29590	PML	P28482	MAPK1	T867	R872H	872	Missense	distal	5	no	17.434	17.257	EPSD	COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P29590	PML	P28482	MAPK1	S879	Q881R	881	Missense	proximal	2	no	8.027	8.318	EPSD	COSMIC	8.102	Gain
CMGC_MAPK_ERK1_MAPK1_ST	Q15700	DLG2	P28482	MAPK1	S65	S62R	62	Missense	distal	-3	no	13.967	14.124	EPSD	COSMIC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q15700	DLG2	P28482	MAPK1	S65	S62F	62	Missense	distal	-3	no	13.967	13.734	EPSD	COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q15700	DLG2	P28482	MAPK1	S65	P66L	66	Missense	proximal	1	no	13.967	5.157	EPSD	COSMIC	8.102	Loss
CMGC_MAPK_ERK1_MAPK1_ST	Q15700	DLG2	P28482	MAPK1	S65	I64M	64	Missense	proximal	-1	no	13.967	13.983	EPSD	COSMIC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q15700	DLG2	P28482	MAPK1	S65	S70T	70	Missense	distal	5	no	13.967	13.893	EPSD	COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q15700	DLG2	P28482	MAPK1	S323	G325R	325	Missense	proximal	2	no	19.443	19.538	PhosphoSitePlus	COSMIC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q15700	DLG2	P28482	MAPK1	S323	L319M	319	Missense	distal	-4	no	19.443	19.282	PhosphoSitePlus	COSMIC;CCLE	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q15700	DLG2	P28482	MAPK1	S323	P329L	329	Missense	distal	6	no	19.443	19.036	PhosphoSitePlus	COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q15700	DLG2	P28482	MAPK1	S323	P321L	321	Missense	proximal	-2	no	19.443	17.526	PhosphoSitePlus	COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q15700	DLG2	P28482	MAPK1	S323	P324L	324	Missense	proximal	1	no	19.443	10.633	PhosphoSitePlus	COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q15700	DLG2	P28482	MAPK1	S323	S323F	323	Missense	central	0	yes	19.443	0.000	PhosphoSitePlus	COSMIC	8.102	Loss
CMGC_MAPK_ERK1_MAPK1_ST	Q15700	DLG2	P28482	MAPK1	S323	R326G	326	Missense	distal	3	no	19.443	19.481	PhosphoSitePlus	COSMIC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q15700	DLG2	P28482	MAPK1	S323	R326M	326	Missense	distal	3	no	19.443	19.482	PhosphoSitePlus	COSMIC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q15700	DLG2	P28482	MAPK1	S323	P324S	324	Missense	proximal	1	no	19.443	10.048	PhosphoSitePlus	COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q15700	DLG2	P28482	MAPK1	S328	G325R	325	Missense	distal	-3	no	13.340	13.509	EPSD	COSMIC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q15700	DLG2	P28482	MAPK1	S328	K332N	332	Missense	distal	4	no	13.340	13.315	EPSD	COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q15700	DLG2	P28482	MAPK1	S328	P329L	329	Missense	proximal	1	no	13.340	4.530	EPSD	COSMIC	8.102	Loss
CMGC_MAPK_ERK1_MAPK1_ST	Q15700	DLG2	P28482	MAPK1	S328	P321L	321	Missense	distal	-7	no	13.340	13.327	EPSD	COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q15700	DLG2	P28482	MAPK1	S328	P324L	324	Missense	distal	-4	no	13.340	13.035	EPSD	COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q15700	DLG2	P28482	MAPK1	S328	K332T	332	Missense	distal	4	no	13.340	13.239	EPSD	COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q15700	DLG2	P28482	MAPK1	S328	S323F	323	Missense	distal	-5	no	13.340	13.428	EPSD	COSMIC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q15700	DLG2	P28482	MAPK1	S328	R326G	326	Missense	proximal	-2	no	13.340	11.964	EPSD	COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q15700	DLG2	P28482	MAPK1	S328	P331L	331	Missense	distal	3	no	13.340	13.429	EPSD	COSMIC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q15700	DLG2	P28482	MAPK1	S328	L335I	335	Missense	distal	7	no	13.340	13.599	EPSD	COSMIC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q15700	DLG2	P28482	MAPK1	S328	R326M	326	Missense	proximal	-2	no	13.340	11.144	EPSD	COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q15700	DLG2	P28482	MAPK1	S328	P324S	324	Missense	distal	-4	no	13.340	13.256	EPSD	COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q15700	DLG2	P28482	MAPK1	S360	P358H	358	Missense	proximal	-2	no	16.803	14.048	EPSD	COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q15700	DLG2	P28482	MAPK1	S360	K357M	357	Missense	distal	-3	no	16.803	16.623	EPSD	COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q15700	DLG2	P28482	MAPK1	S360	C355Y	355	Missense	distal	-5	no	16.803	16.731	EPSD	COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q15700	DLG2	P28482	MAPK1	S360	C355R	355	Missense	distal	-5	no	16.803	16.573	EPSD	COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q15700	DLG2	P28482	MAPK1	S360	K357T	357	Missense	distal	-3	no	16.803	16.852	EPSD	COSMIC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q15700	DLG2	P28482	MAPK1	S360	D356N	356	Missense	distal	-4	no	16.803	16.775	EPSD	COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q15700	DLG2	P28482	MAPK1	S360	V367M	367	Missense	distal	7	no	16.803	16.880	EPSD	COSMIC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q15700	DLG2	P28482	MAPK1	S365	K371N	371	Missense	distal	6	no	14.400	14.247	EPSD	COSMIC;GDSC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q15700	DLG2	P28482	MAPK1	S365	P358H	358	Missense	distal	-7	no	14.400	14.384	EPSD	COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q15700	DLG2	P28482	MAPK1	S365	K371T	371	Missense	distal	6	no	14.400	14.133	EPSD	COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q15700	DLG2	P28482	MAPK1	S365	D370G	370	Missense	distal	5	no	14.400	14.356	EPSD	COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q15700	DLG2	P28482	MAPK1	S365	C369S	369	Missense	distal	4	no	14.400	14.682	EPSD	COSMIC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q15700	DLG2	P28482	MAPK1	S365	D370V	370	Missense	distal	5	no	14.400	14.232	EPSD	COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q15700	DLG2	P28482	MAPK1	S365	D370H	370	Missense	distal	5	no	14.400	14.230	EPSD	COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q15700	DLG2	P28482	MAPK1	S365	V367M	367	Missense	proximal	2	no	14.400	14.263	EPSD	COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q15700	DLG2	P28482	MAPK1	S635	R640W	640	Missense	distal	5	no	8.685	8.156	EPSD	COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q15700	DLG2	P28482	MAPK1	S635	S635I	635	Missense	central	0	yes	8.685	0.000	EPSD	COSMIC	8.102	Loss
CMGC_MAPK_ERK1_MAPK1_ST	Q15700	DLG2	P28482	MAPK1	S635	R632H	632	Missense	distal	-3	no	8.685	8.355	EPSD	COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q15700	DLG2	P28482	MAPK1	S635	K631E	631	Missense	distal	-4	no	8.685	8.667	EPSD	COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q15700	DLG2	P28482	MAPK1	S635	S635N	635	Missense	central	0	yes	8.685	0.000	EPSD	COSMIC	8.102	Loss
CMGC_MAPK_ERK1_MAPK1_ST	Q15700	DLG2	P28482	MAPK1	S635	R640Q	640	Missense	distal	5	no	8.685	8.515	EPSD	COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q15700	DLG2	P28482	MAPK1	S800	S800F	800	Missense	central	0	yes	9.268	0.000	EPSD	COSMIC	8.102	Loss
CMGC_MAPK_ERK1_MAPK1_ST	Q15700	DLG2	P28482	MAPK1	S800	S800Y	800	Missense	central	0	yes	9.268	0.000	EPSD	COSMIC	8.102	Loss
CMGC_MAPK_ERK1_MAPK1_ST	Q15700	DLG2	P28482	MAPK1	S800	K797N	797	Missense	distal	-3	no	9.268	9.365	EPSD	COSMIC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q15700	DLG2	P28482	MAPK1	S800	M805V	805	Missense	distal	5	no	9.268	9.330	EPSD	COSMIC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q9NRA0	SPHK2	P28482	MAPK1	S107	T102P	102	Missense	distal	-5	no	14.398	14.295	EPSD	COSMIC;GDSC;CCLE	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q9NRA0	SPHK2	P28482	MAPK1	S107	S105N	105	Missense	proximal	-2	no	14.398	14.412	EPSD	COSMIC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q9NRA0	SPHK2	P28482	MAPK1	S107	R104W	104	Missense	distal	-3	no	14.398	13.699	EPSD	COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q9NRA0	SPHK2	P28482	MAPK1	S107	R104Q	104	Missense	distal	-3	no	14.398	14.120	EPSD	COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q9NRA0	SPHK2	P28482	MAPK1	S107	A112V	112	Missense	distal	5	no	14.398	14.415	EPSD	COSMIC;GDSC;CCLE	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q9NRA0	SPHK2	P28482	MAPK1	S387	P380L	380	Missense	distal	-7	no	16.526	16.513	PhosphoSitePlus;EPSD	COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q9NRA0	SPHK2	P28482	MAPK1	S387	P380H	380	Missense	distal	-7	no	16.526	16.509	PhosphoSitePlus;EPSD	COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q9NRA0	SPHK2	P28482	MAPK1	T389	R396H	396	Missense	distal	7	no	11.999	12.218	EPSD	COSMIC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q9NRA0	SPHK2	P28482	MAPK1	T404	S399L	399	Missense	distal	-5	no	14.535	14.610	EPSD	COSMIC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q9NRA0	SPHK2	P28482	MAPK1	T404	P407Q	407	Missense	distal	3	no	14.535	14.603	EPSD	COSMIC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q9NRA0	SPHK2	P28482	MAPK1	T404	D406G	406	Missense	proximal	2	no	14.535	14.569	EPSD	COSMIC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q9NRA0	SPHK2	P28482	MAPK1	T404	A397T	397	Missense	distal	-7	no	14.535	14.521	EPSD	COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q9NRA0	SPHK2	P28482	MAPK1	T404	P405Q	405	Missense	proximal	1	no	14.535	6.042	EPSD	COSMIC	8.102	Loss
CMGC_MAPK_ERK1_MAPK1_ST	Q9NRA0	SPHK2	P28482	MAPK1	T404	P405L	405	Missense	proximal	1	no	14.535	5.725	EPSD	COSMIC	8.102	Loss
CMGC_MAPK_ERK1_MAPK1_ST	Q9NRA0	SPHK2	P28482	MAPK1	T404	P405S	405	Missense	proximal	1	no	14.535	5.140	EPSD	COSMIC	8.102	Loss
CMGC_MAPK_ERK1_MAPK1_ST	Q9NRA0	SPHK2	P28482	MAPK1	S414	S419F	419	Missense	distal	5	no	12.711	12.514	EPSD	COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q9NRA0	SPHK2	P28482	MAPK1	S414	H417N	417	Missense	distal	3	no	12.711	12.613	EPSD	COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q9NRA0	SPHK2	P28482	MAPK1	S414	R418C	418	Missense	distal	4	no	12.711	12.452	EPSD	COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q9NRA0	SPHK2	P28482	MAPK1	S414	P407Q	407	Missense	distal	-7	no	12.711	12.714	EPSD	COSMIC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q9NRA0	SPHK2	P28482	MAPK1	S473	P469L	469	Missense	distal	-4	no	14.889	14.585	EPSD	COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q9NRA0	SPHK2	P28482	MAPK1	S484	E488K	488	Missense	distal	4	no	15.493	15.507	EPSD	COSMIC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q9NRA0	SPHK2	P28482	MAPK1	S487	E488K	488	Missense	proximal	1	no	8.508	-1.240	EPSD	COSMIC	8.102	Loss
CMGC_MAPK_ERK1_MAPK1_ST	Q9NRA0	SPHK2	P28482	MAPK1	S487	V492I	492	Missense	distal	5	no	8.508	8.333	EPSD	COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q9NRA0	SPHK2	P28482	MAPK1	T503	S496P	496	Missense	distal	-7	no	13.576	13.580	EPSD	COSMIC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q9NRA0	SPHK2	P28482	MAPK1	T503	R507Q	507	Missense	distal	4	no	13.576	13.501	EPSD	COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q9NRA0	SPHK2	P28482	MAPK1	T614	G617S	617	Missense	distal	3	no	15.533	15.519	EPSD;PhosphoSitePlus	COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q9NRA0	SPHK2	P28482	MAPK1	T614	T620A	620	Missense	distal	6	no	15.533	15.447	EPSD;PhosphoSitePlus	COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q9NRA0	SPHK2	P28482	MAPK1	T641	G645W	645	Missense	distal	4	no	8.489	8.232	EPSD	COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P35236	PTPN7	P28482	MAPK1	T30	E28K	28	Missense	proximal	-2	no	15.426	15.386	EPSD	COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P35236	PTPN7	P28482	MAPK1	T30	P25S	25	Missense	distal	-5	no	15.426	15.500	EPSD	COSMIC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P35236	PTPN7	P28482	MAPK1	T30	T30M	30	Missense	central	0	yes	15.426	0.000	EPSD	COSMIC	8.102	Loss
CMGC_MAPK_ERK1_MAPK1_ST	P35236	PTPN7	P28482	MAPK1	S54	G56V	56	Missense	proximal	2	no	8.581	8.509	EPSD	COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P35236	PTPN7	P28482	MAPK1	S54	M49I	49	Missense	distal	-5	no	8.581	8.638	EPSD	COSMIC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P35236	PTPN7	P28482	MAPK1	S54	A57V	57	Missense	distal	3	no	8.581	8.560	EPSD	COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P35236	PTPN7	P28482	MAPK1	S54	V58A	58	Missense	distal	4	no	8.581	8.587	EPSD	COSMIC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P35236	PTPN7	P28482	MAPK1	S54	P60L	60	Missense	distal	6	no	8.581	8.175	EPSD	COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P35236	PTPN7	P28482	MAPK1	S54	R53Q	53	Missense	proximal	-1	no	8.581	8.560	EPSD	COSMIC;CCLE	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P35236	PTPN7	P28482	MAPK1	T66	R68Q	68	Missense	proximal	2	no	14.843	14.552	PhosphoSitePlus;EPSD	COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P35236	PTPN7	P28482	MAPK1	T66	P60L	60	Missense	distal	-6	no	14.843	14.752	PhosphoSitePlus;EPSD	COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P35236	PTPN7	P28482	MAPK1	T66	R68L	68	Missense	proximal	2	no	14.843	14.583	PhosphoSitePlus;EPSD	COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P35236	PTPN7	P28482	MAPK1	T66	R68P	68	Missense	proximal	2	no	14.843	14.730	PhosphoSitePlus;EPSD	COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P35236	PTPN7	P28482	MAPK1	T66	E69G	69	Missense	distal	3	no	14.843	14.936	PhosphoSitePlus;EPSD	COSMIC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P35236	PTPN7	P28482	MAPK1	S93	A86D	86	Missense	distal	-7	no	17.799	17.798	EPSD;PhosphoSitePlus	COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P35236	PTPN7	P28482	MAPK1	S93	R89H	89	Missense	distal	-4	no	17.799	17.647	EPSD;PhosphoSitePlus	COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P35236	PTPN7	P28482	MAPK1	S93	L87F	87	Missense	distal	-6	no	17.799	17.781	EPSD;PhosphoSitePlus	COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P35236	PTPN7	P28482	MAPK1	S93	E100Q	100	Missense	distal	7	no	17.799	17.977	EPSD;PhosphoSitePlus	COSMIC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P35236	PTPN7	P28482	MAPK1	S134	P130S	130	Missense	distal	-4	no	8.273	8.189	EPSD	COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P05412	JUN	P28482	MAPK1	S21	N15D	15	Missense	distal	-6	no	8.115	8.161	EPSD	COSMIC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P05412	JUN	P28482	MAPK1	S21	G27D	27	Missense	distal	6	no	8.115	8.147	EPSD	COSMIC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P05412	JUN	P28482	MAPK1	S63	L61F	61	Missense	proximal	-2	no	13.422	12.699	EPSD;PhosphoSitePlus	COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P05412	JUN	P28482	MAPK1	S73	R78H	78	Missense	distal	5	no	14.757	14.580	PhosphoSitePlus;EPSD	COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P05412	JUN	P28482	MAPK1	T91	P92Q	92	Missense	proximal	1	no	13.961	5.468	EPSD	COSMIC	8.102	Loss
CMGC_MAPK_ERK1_MAPK1_ST	P05412	JUN	P28482	MAPK1	T91	L98M	98	Missense	distal	7	no	13.961	14.032	EPSD	COSMIC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P05412	JUN	P28482	MAPK1	T91	P94S	94	Missense	distal	3	no	13.961	14.030	EPSD	COSMIC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P05412	JUN	P28482	MAPK1	T93	P100L	100	Missense	distal	7	no	11.641	11.940	EPSD	COSMIC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P05412	JUN	P28482	MAPK1	T93	P92Q	92	Missense	proximal	-1	no	11.641	11.600	EPSD	COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P05412	JUN	P28482	MAPK1	T93	L98M	98	Missense	distal	5	no	11.641	11.667	EPSD	COSMIC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P05412	JUN	P28482	MAPK1	T93	P94S	94	Missense	proximal	1	no	11.641	2.246	EPSD	COSMIC	8.102	Loss
CMGC_MAPK_ERK1_MAPK1_ST	P05412	JUN	P28482	MAPK1	T239	P240Q	240	Missense	proximal	1	no	14.415	5.921	EPSD	COSMIC	8.102	Loss
CMGC_MAPK_ERK1_MAPK1_ST	P05412	JUN	P28482	MAPK1	T239	T239I	239	Missense	central	0	yes	14.415	0.000	EPSD	COSMIC	8.102	Loss
CMGC_MAPK_ERK1_MAPK1_ST	P05412	JUN	P28482	MAPK1	S243	P240Q	240	Missense	distal	-3	no	15.977	15.680	EPSD	COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P05412	JUN	P28482	MAPK1	S243	T239I	239	Missense	distal	-4	no	15.977	15.620	EPSD	COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q02750	MAP2K1	P28482	MAPK1	S18	S24Y	24	Missense	distal	6	no	8.439	7.821	EPSD	COSMIC	8.102	Loss
CMGC_MAPK_ERK1_MAPK1_ST	Q02750	MAP2K1	P28482	MAPK1	S18	G22V	22	Missense	distal	4	no	8.439	8.390	EPSD	COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q02750	MAP2K1	P28482	MAPK1	S18	S18A	18	Missense	central	0	yes	8.439	0.000	EPSD	COSMIC	8.102	Loss
CMGC_MAPK_ERK1_MAPK1_ST	Q02750	MAP2K1	P28482	MAPK1	S18	P15S	15	Missense	distal	-3	no	8.439	8.263	EPSD	COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q02750	MAP2K1	P28482	MAPK1	S25	S24Y	24	Missense	proximal	-1	no	9.924	9.893	EPSD	COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q02750	MAP2K1	P28482	MAPK1	S25	E27V	27	Missense	proximal	2	no	9.924	9.938	EPSD	COSMIC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q02750	MAP2K1	P28482	MAPK1	S25	G22V	22	Missense	distal	-3	no	9.924	9.806	EPSD	COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q02750	MAP2K1	P28482	MAPK1	S25	S18A	18	Missense	distal	-7	no	9.924	9.926	EPSD	COSMIC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q02750	MAP2K1	P28482	MAPK1	S25	L30F	30	Missense	distal	5	no	9.924	9.958	EPSD	COSMIC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q02750	MAP2K1	P28482	MAPK1	S231	Y229H	229	Missense	proximal	-2	no	16.182	15.545	EPSD	COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q02750	MAP2K1	P28482	MAPK1	T286	A283V	283	Missense	distal	-3	no	12.915	12.975	PhosphoSitePlus;EPSD	COSMIC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q02750	MAP2K1	P28482	MAPK1	T286	P293S	293	Missense	distal	7	no	12.915	12.926	PhosphoSitePlus;EPSD	COSMIC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q02750	MAP2K1	P28482	MAPK1	T286	R291K	291	Missense	distal	5	no	12.915	12.780	PhosphoSitePlus;EPSD	COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q02750	MAP2K1	P28482	MAPK1	T292	P293S	293	Missense	proximal	1	no	18.747	9.352	EPSD;PhosphoSitePlus	COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q02750	MAP2K1	P28482	MAPK1	T292	R291K	291	Missense	proximal	-1	no	18.747	18.780	EPSD;PhosphoSitePlus	COSMIC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q02750	MAP2K1	P28482	MAPK1	S299	P306H	306	Missense	distal	7	no	9.200	9.434	EPSD	COSMIC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q02750	MAP2K1	P28482	MAPK1	S299	G301E	301	Missense	proximal	2	no	9.200	9.114	EPSD	COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q02750	MAP2K1	P28482	MAPK1	S299	P293S	293	Missense	distal	-6	no	9.200	9.174	EPSD	COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q02750	MAP2K1	P28482	MAPK1	S377	L375P	375	Missense	proximal	-2	no	8.277	10.194	EPSD	COSMIC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q02750	MAP2K1	P28482	MAPK1	S377	S377F	377	Missense	central	0	yes	8.277	0.000	EPSD	COSMIC	8.102	Loss
CMGC_MAPK_ERK1_MAPK1_ST	Q02750	MAP2K1	P28482	MAPK1	S377	N382H	382	Missense	distal	5	no	8.277	8.205	EPSD	COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q02750	MAP2K1	P28482	MAPK1	T386	P387S	387	Missense	proximal	1	no	18.316	8.921	EPSD;PhosphoSitePlus	COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q02750	MAP2K1	P28482	MAPK1	T386	A390T	390	Missense	distal	4	no	18.316	18.297	EPSD;PhosphoSitePlus	COSMIC;GDSC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q02750	MAP2K1	P28482	MAPK1	T386	N382H	382	Missense	distal	-4	no	18.316	18.117	EPSD;PhosphoSitePlus	COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P32004	L1CAM	P28482	MAPK1	S163	A164V	164	Missense	proximal	1	no	10.716	8.806	EPSD	COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P32004	L1CAM	P28482	MAPK1	S163	P166L	166	Missense	distal	3	no	10.716	10.805	EPSD	COSMIC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P32004	L1CAM	P28482	MAPK1	S163	R168Q	168	Missense	distal	5	no	10.716	10.546	EPSD	COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P32004	L1CAM	P28482	MAPK1	S163	L167P	167	Missense	distal	4	no	10.716	10.836	EPSD	COSMIC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P32004	L1CAM	P28482	MAPK1	S163	P157S	157	Missense	distal	-6	no	10.716	10.690	EPSD	COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P32004	L1CAM	P28482	MAPK1	S163	P161L	161	Missense	proximal	-2	no	10.716	8.798	EPSD	COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P32004	L1CAM	P28482	MAPK1	S701	E705D	705	Missense	distal	4	no	14.139	14.069	EPSD	COSMIC;CCLE	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P32004	L1CAM	P28482	MAPK1	S701	P697L	697	Missense	distal	-4	no	14.139	13.835	EPSD	COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P32004	L1CAM	P28482	MAPK1	T709	E705D	705	Missense	distal	-4	no	14.926	14.941	EPSD	COSMIC;CCLE	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P32004	L1CAM	P28482	MAPK1	S793	A790D	790	Missense	distal	-3	no	7.993	8.231	EPSD	COSMIC	8.102	Gain
CMGC_MAPK_ERK1_MAPK1_ST	P32004	L1CAM	P28482	MAPK1	S1204	I1199M	1199	Missense	distal	-5	no	8.733	8.677	EPSD;PhosphoSitePlus	COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P32004	L1CAM	P28482	MAPK1	S1204	L1202P	1202	Missense	proximal	-2	no	8.733	10.651	EPSD;PhosphoSitePlus	COSMIC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P32004	L1CAM	P28482	MAPK1	S1204	L1202M	1202	Missense	proximal	-2	no	8.733	6.636	EPSD;PhosphoSitePlus	COSMIC	8.102	Loss
CMGC_MAPK_ERK1_MAPK1_ST	P32004	L1CAM	P28482	MAPK1	S1248	V1254M	1254	Missense	distal	6	no	15.506	15.288	PhosphoSitePlus;EPSD	COSMIC;GDSC;CCLE	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P32004	L1CAM	P28482	MAPK1	S1248	A1253T	1253	Missense	distal	5	no	15.506	15.592	PhosphoSitePlus;EPSD	COSMIC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P32004	L1CAM	P28482	MAPK1	S1248	A1255D	1255	Missense	distal	7	no	15.506	15.321	PhosphoSitePlus;EPSD	COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P32004	L1CAM	P28482	MAPK1	S1248	A1246D	1246	Missense	proximal	-2	no	15.506	15.351	PhosphoSitePlus;EPSD	COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q16665	HIF1A	P28482	MAPK1	S15	R18G	18	Missense	distal	3	no	9.164	9.201	EPSD	COSMIC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q16665	HIF1A	P28482	MAPK1	S15	R18H	18	Missense	distal	3	no	9.164	9.206	EPSD	COSMIC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q16665	HIF1A	P28482	MAPK1	S15	S15R	15	Missense	central	0	yes	9.164	0.000	EPSD	COSMIC	8.102	Loss
CMGC_MAPK_ERK1_MAPK1_ST	Q16665	HIF1A	P28482	MAPK1	S15	R17H	17	Missense	proximal	2	no	9.164	8.920	EPSD	COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q16665	HIF1A	P28482	MAPK1	S15	S14R	14	Missense	proximal	-1	no	9.164	9.188	EPSD	COSMIC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q16665	HIF1A	P28482	MAPK1	S15	S22Y	22	Missense	distal	7	no	9.164	9.681	EPSD	COSMIC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q16665	HIF1A	P28482	MAPK1	S15	E20K	20	Missense	distal	5	no	9.164	9.104	EPSD	COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q16665	HIF1A	P28482	MAPK1	S65	S58Y	58	Missense	distal	-7	no	9.504	9.473	EPSD	COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q16665	HIF1A	P28482	MAPK1	S65	R68P	68	Missense	distal	3	no	9.504	9.458	EPSD	COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q16665	HIF1A	P28482	MAPK1	S65	I64M	64	Missense	proximal	-1	no	9.504	9.520	EPSD	COSMIC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q16665	HIF1A	P28482	MAPK1	S65	Y66C	66	Missense	proximal	1	no	9.504	3.065	EPSD	COSMIC	8.102	Loss
CMGC_MAPK_ERK1_MAPK1_ST	Q16665	HIF1A	P28482	MAPK1	S451	P452A	452	Missense	proximal	1	no	14.232	6.601	EPSD	COSMIC	8.102	Loss
CMGC_MAPK_ERK1_MAPK1_ST	Q16665	HIF1A	P28482	MAPK1	S451	A456T	456	Missense	distal	5	no	14.232	14.318	EPSD	COSMIC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q16665	HIF1A	P28482	MAPK1	S451	A456S	456	Missense	distal	5	no	14.232	14.391	EPSD	COSMIC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q16665	HIF1A	P28482	MAPK1	S451	N447K	447	Missense	distal	-4	no	14.232	14.263	EPSD	COSMIC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q16665	HIF1A	P28482	MAPK1	T458	P452A	452	Missense	distal	-6	no	12.817	12.777	EPSD	COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q16665	HIF1A	P28482	MAPK1	T458	A456T	456	Missense	proximal	-2	no	12.817	13.264	EPSD	COSMIC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q16665	HIF1A	P28482	MAPK1	T458	A456S	456	Missense	proximal	-2	no	12.817	13.129	EPSD	COSMIC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q16665	HIF1A	P28482	MAPK1	S500	Q497H	497	Missense	distal	-3	no	14.910	14.857	EPSD	COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q16665	HIF1A	P28482	MAPK1	S500	R507K	507	Missense	distal	7	no	14.910	14.855	EPSD	COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q16665	HIF1A	P28482	MAPK1	S500	P501L	501	Missense	proximal	1	no	14.910	6.100	EPSD	COSMIC	8.102	Loss
CMGC_MAPK_ERK1_MAPK1_ST	Q16665	HIF1A	P28482	MAPK1	S500	Q495K	495	Missense	distal	-5	no	14.910	14.787	EPSD	COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q16665	HIF1A	P28482	MAPK1	S500	Q495R	495	Missense	distal	-5	no	14.910	14.832	EPSD	COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q16665	HIF1A	P28482	MAPK1	S500	D503N	503	Missense	distal	3	no	14.910	14.814	EPSD	COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q16665	HIF1A	P28482	MAPK1	S510	R507K	507	Missense	distal	-3	no	13.315	13.077	EPSD	COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q16665	HIF1A	P28482	MAPK1	S510	E512V	512	Missense	proximal	2	no	13.315	13.329	EPSD	COSMIC;GDSC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q16665	HIF1A	P28482	MAPK1	S510	P516H	516	Missense	distal	6	no	13.315	13.010	EPSD	COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q16665	HIF1A	P28482	MAPK1	S510	S517T	517	Missense	distal	7	no	13.315	13.467	EPSD	COSMIC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q16665	HIF1A	P28482	MAPK1	S510	D503N	503	Missense	distal	-7	no	13.315	13.316	EPSD	COSMIC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q16665	HIF1A	P28482	MAPK1	S515	E512V	512	Missense	distal	-3	no	16.373	16.246	EPSD	COSMIC;GDSC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q16665	HIF1A	P28482	MAPK1	S515	P516H	516	Missense	proximal	1	no	16.373	8.549	EPSD	COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q16665	HIF1A	P28482	MAPK1	S515	S517T	517	Missense	proximal	2	no	16.373	16.350	EPSD	COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q16665	HIF1A	P28482	MAPK1	S515	Y522H	522	Missense	distal	7	no	16.373	16.078	EPSD	COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q16665	HIF1A	P28482	MAPK1	S551	K547N	547	Missense	distal	-4	no	8.508	8.476	EPSD	COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q16665	HIF1A	P28482	MAPK1	S551	Q553K	553	Missense	proximal	2	no	8.508	8.618	EPSD	COSMIC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q16665	HIF1A	P28482	MAPK1	S551	Q553H	553	Missense	proximal	2	no	8.508	8.556	EPSD	COSMIC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q16665	HIF1A	P28482	MAPK1	S589	Q596E	596	Missense	distal	7	no	11.863	11.685	EPSD	COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q16665	HIF1A	P28482	MAPK1	S589	A588T	588	Missense	proximal	-1	no	11.863	11.857	EPSD	COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q16665	HIF1A	P28482	MAPK1	S589	A588P	588	Missense	proximal	-1	no	11.863	11.900	EPSD	COSMIC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q16665	HIF1A	P28482	MAPK1	S589	P582S	582	Missense	distal	-7	no	11.863	11.858	EPSD	COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q16665	HIF1A	P28482	MAPK1	S589	A593T	593	Missense	distal	4	no	11.863	11.843	EPSD	COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q16665	HIF1A	P28482	MAPK1	S589	E584Q	584	Missense	distal	-5	no	11.863	11.962	EPSD	COSMIC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q16665	HIF1A	P28482	MAPK1	S589	E584D	584	Missense	distal	-5	no	11.863	11.908	EPSD	COSMIC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q16665	HIF1A	P28482	MAPK1	S641	I635F	635	Missense	distal	-6	no	13.583	13.600	EPSD;PhosphoSitePlus	COSMIC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q16665	HIF1A	P28482	MAPK1	S641	A640P	640	Missense	proximal	-1	no	13.583	13.620	EPSD;PhosphoSitePlus	COSMIC;GDSC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q16665	HIF1A	P28482	MAPK1	S641	P642S	642	Missense	proximal	1	no	13.583	4.188	EPSD;PhosphoSitePlus	COSMIC	8.102	Loss
CMGC_MAPK_ERK1_MAPK1_ST	Q16665	HIF1A	P28482	MAPK1	S641	K636N	636	Missense	distal	-5	no	13.583	13.606	EPSD;PhosphoSitePlus	COSMIC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q16665	HIF1A	P28482	MAPK1	S643	A640P	640	Missense	distal	-3	no	14.245	14.612	PhosphoSitePlus;EPSD	COSMIC;GDSC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q16665	HIF1A	P28482	MAPK1	S643	P642S	642	Missense	proximal	-1	no	14.245	14.202	PhosphoSitePlus;EPSD	COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q16665	HIF1A	P28482	MAPK1	S668	R671K	671	Missense	distal	3	no	13.191	13.142	EPSD	COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q16665	HIF1A	P28482	MAPK1	S668	T666S	666	Missense	proximal	-2	no	13.191	13.056	EPSD	COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q16665	HIF1A	P28482	MAPK1	S668	A672V	672	Missense	distal	4	no	13.191	13.185	EPSD	COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q16665	HIF1A	P28482	MAPK1	S687	E681D	681	Missense	distal	-6	no	16.981	16.993	EPSD	COSMIC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q16665	HIF1A	P28482	MAPK1	S687	P685Q	685	Missense	proximal	-2	no	16.981	13.988	EPSD	COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q16665	HIF1A	P28482	MAPK1	S687	V690M	690	Missense	distal	3	no	16.981	17.009	EPSD	COSMIC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q16665	HIF1A	P28482	MAPK1	S687	A694T	694	Missense	distal	7	no	16.981	16.952	EPSD	COSMIC;GDSC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q16665	HIF1A	P28482	MAPK1	S687	N689I	689	Missense	proximal	2	no	16.981	16.887	EPSD	COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q16665	HIF1A	P28482	MAPK1	S687	K682Q	682	Missense	distal	-5	no	16.981	17.104	EPSD	COSMIC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q16665	HIF1A	P28482	MAPK1	S687	S692F	692	Missense	distal	5	no	16.981	16.784	EPSD	COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q08499	PDE4D	P28482	MAPK1	S14	G13S	13	Missense	proximal	-1	no	8.133	8.144	EPSD	COSMIC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q08499	PDE4D	P28482	MAPK1	S14	A10V	10	Missense	distal	-4	no	8.133	8.073	EPSD	COSMIC	8.102	Loss
CMGC_MAPK_ERK1_MAPK1_ST	Q08499	PDE4D	P28482	MAPK1	S14	R11Q	11	Missense	distal	-3	no	8.133	7.856	EPSD	COSMIC	8.102	Loss
CMGC_MAPK_ERK1_MAPK1_ST	Q08499	PDE4D	P28482	MAPK1	S18	G13S	13	Missense	distal	-5	no	9.011	9.017	EPSD	COSMIC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q08499	PDE4D	P28482	MAPK1	S18	G22S	22	Missense	distal	4	no	9.011	9.060	EPSD	COSMIC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q08499	PDE4D	P28482	MAPK1	S18	R11Q	11	Missense	distal	-7	no	9.011	9.019	EPSD	COSMIC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q08499	PDE4D	P28482	MAPK1	S164	D167N	167	Missense	distal	3	no	13.051	12.956	EPSD	COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q08499	PDE4D	P28482	MAPK1	S164	S171N	171	Missense	distal	7	no	13.051	13.034	EPSD	COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q08499	PDE4D	P28482	MAPK1	S171	D167N	167	Missense	distal	-4	no	13.993	13.965	EPSD	COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q08499	PDE4D	P28482	MAPK1	S171	S171N	171	Missense	central	0	yes	13.993	0.000	EPSD	COSMIC	8.102	Loss
CMGC_MAPK_ERK1_MAPK1_ST	Q08499	PDE4D	P28482	MAPK1	S171	L176P	176	Missense	distal	5	no	13.993	14.206	EPSD	COSMIC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q08499	PDE4D	P28482	MAPK1	S202	R208Q	208	Missense	distal	6	no	12.862	12.682	EPSD	COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q08499	PDE4D	P28482	MAPK1	S202	S207F	207	Missense	distal	5	no	12.862	12.665	EPSD	COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q08499	PDE4D	P28482	MAPK1	S348	P349S	349	Missense	proximal	1	no	14.264	4.869	EPSD	COSMIC	8.102	Loss
CMGC_MAPK_ERK1_MAPK1_ST	Q08499	PDE4D	P28482	MAPK1	S348	S348F	348	Missense	central	0	yes	14.264	0.000	EPSD	COSMIC	8.102	Loss
CMGC_MAPK_ERK1_MAPK1_ST	Q08499	PDE4D	P28482	MAPK1	S362	Q363P	363	Missense	proximal	1	no	10.937	19.431	EPSD	COSMIC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q08499	PDE4D	P28482	MAPK1	S374	S375F	375	Missense	proximal	1	no	6.455	9.281	EPSD	COSMIC	8.102	Gain
CMGC_MAPK_ERK1_MAPK1_ST	Q08499	PDE4D	P28482	MAPK1	S657	E655G	655	Missense	proximal	-2	no	12.270	11.456	EPSD	COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q08499	PDE4D	P28482	MAPK1	S715	P716S	716	Missense	proximal	1	no	17.970	8.575	EPSD	COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q08499	PDE4D	P28482	MAPK1	S715	P718S	718	Missense	distal	3	no	17.970	18.039	EPSD	COSMIC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q08499	PDE4D	P28482	MAPK1	S717	P716S	716	Missense	proximal	-1	no	12.429	12.386	EPSD	COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q08499	PDE4D	P28482	MAPK1	S717	P718S	718	Missense	proximal	1	no	12.429	3.034	EPSD	COSMIC	8.102	Loss
CMGC_MAPK_ERK1_MAPK1_ST	Q08499	PDE4D	P28482	MAPK1	S806	R805L	805	Missense	proximal	-1	no	15.209	15.168	EPSD	COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q08499	PDE4D	P28482	MAPK1	S806	S806A	806	Missense	central	0	yes	15.209	0.000	EPSD	COSMIC	8.102	Loss
CMGC_MAPK_ERK1_MAPK1_ST	Q3V6T2	CCDC88A	P28482	MAPK1	S16	T15A	15	Missense	proximal	-1	no	13.968	13.973	EPSD	COSMIC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q3V6T2	CCDC88A	P28482	MAPK1	S233	S229C	229	Missense	distal	-4	no	13.645	13.001	PhosphoSitePlus;EPSD	COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q3V6T2	CCDC88A	P28482	MAPK1	S233	S228T	228	Missense	distal	-5	no	13.645	13.674	PhosphoSitePlus;EPSD	COSMIC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q3V6T2	CCDC88A	P28482	MAPK1	S237	R242Q	242	Missense	distal	5	no	13.613	13.443	EPSD;PhosphoSitePlus	COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q3V6T2	CCDC88A	P28482	MAPK1	S1020	Q1018H	1018	Missense	proximal	-2	no	14.011	14.250	EPSD	COSMIC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q3V6T2	CCDC88A	P28482	MAPK1	S1020	R1015M	1015	Missense	distal	-5	no	14.011	14.116	EPSD	COSMIC;CCLE	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q3V6T2	CCDC88A	P28482	MAPK1	S1020	R1015K	1015	Missense	distal	-5	no	14.011	13.967	EPSD	COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q3V6T2	CCDC88A	P28482	MAPK1	S1020	Q1018K	1018	Missense	proximal	-2	no	14.011	14.586	EPSD	COSMIC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q3V6T2	CCDC88A	P28482	MAPK1	S1387	K1382T	1382	Missense	distal	-5	no	11.870	11.970	EPSD	COSMIC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q3V6T2	CCDC88A	P28482	MAPK1	S1387	S1387C	1387	Missense	central	0	yes	11.870	0.000	EPSD	COSMIC	8.102	Loss
CMGC_MAPK_ERK1_MAPK1_ST	Q3V6T2	CCDC88A	P28482	MAPK1	S1387	F1383C	1383	Missense	distal	-4	no	11.870	11.488	EPSD	COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q3V6T2	CCDC88A	P28482	MAPK1	S1387	F1383V	1383	Missense	distal	-4	no	11.870	11.861	EPSD	COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q3V6T2	CCDC88A	P28482	MAPK1	S1387	P1388L	1388	Missense	proximal	1	no	11.870	3.061	EPSD	COSMIC	8.102	Loss
CMGC_MAPK_ERK1_MAPK1_ST	Q3V6T2	CCDC88A	P28482	MAPK1	T1421	R1414H	1414	Missense	distal	-7	no	13.471	13.460	EPSD	COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q3V6T2	CCDC88A	P28482	MAPK1	T1421	R1414C	1414	Missense	distal	-7	no	13.471	13.439	EPSD	COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q3V6T2	CCDC88A	P28482	MAPK1	S1439	Q1440P	1440	Missense	proximal	1	no	5.853	14.346	EPSD	COSMIC	8.102	Gain
CMGC_MAPK_ERK1_MAPK1_ST	Q3V6T2	CCDC88A	P28482	MAPK1	S1561	K1557I	1557	Missense	distal	-4	no	8.800	8.140	EPSD	COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q3V6T2	CCDC88A	P28482	MAPK1	S1566	D1572E	1572	Missense	distal	6	no	12.511	12.590	EPSD	COSMIC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q3V6T2	CCDC88A	P28482	MAPK1	S1566	D1572N	1572	Missense	distal	6	no	12.511	12.461	EPSD	COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q3V6T2	CCDC88A	P28482	MAPK1	S1587	R1592T	1592	Missense	distal	5	no	9.713	9.608	EPSD	COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q3V6T2	CCDC88A	P28482	MAPK1	S1587	V1580A	1580	Missense	distal	-7	no	9.713	9.730	EPSD	COSMIC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q3V6T2	CCDC88A	P28482	MAPK1	S1587	A1586T	1586	Missense	proximal	-1	no	9.713	9.708	EPSD	COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q3V6T2	CCDC88A	P28482	MAPK1	S1587	G1591A	1591	Missense	distal	4	no	9.713	9.669	EPSD	COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q3V6T2	CCDC88A	P28482	MAPK1	S1627	L1628F	1628	Missense	proximal	1	no	7.005	9.245	EPSD	COSMIC	8.102	Gain
CMGC_MAPK_ERK1_MAPK1_ST	Q3V6T2	CCDC88A	P28482	MAPK1	S1653	I1660M	1660	Missense	distal	7	no	15.495	15.307	EPSD	COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q3V6T2	CCDC88A	P28482	MAPK1	S1653	R1651T	1651	Missense	proximal	-2	no	15.495	14.614	EPSD	COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q3V6T2	CCDC88A	P28482	MAPK1	S1653	L1656F	1656	Missense	distal	3	no	15.495	15.537	EPSD	COSMIC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q3V6T2	CCDC88A	P28482	MAPK1	T1663	L1664F	1664	Missense	proximal	1	no	6.544	8.784	EPSD	COSMIC	8.102	Gain
CMGC_MAPK_ERK1_MAPK1_ST	Q3V6T2	CCDC88A	P28482	MAPK1	S1675	G1677E	1677	Missense	proximal	2	no	13.899	13.813	EPSD	COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q3V6T2	CCDC88A	P28482	MAPK1	S1675	H1669Y	1669	Missense	distal	-6	no	13.899	13.834	EPSD	COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q3V6T2	CCDC88A	P28482	MAPK1	S1675	H1669R	1669	Missense	distal	-6	no	13.899	13.982	EPSD	COSMIC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q3V6T2	CCDC88A	P28482	MAPK1	T1739	R1746Q	1746	Missense	distal	7	no	12.798	12.913	EPSD	COSMIC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q3V6T2	CCDC88A	P28482	MAPK1	T1739	R1746W	1746	Missense	distal	7	no	12.798	13.770	EPSD	COSMIC;GDSC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q3V6T2	CCDC88A	P28482	MAPK1	T1739	P1740S	1740	Missense	proximal	1	no	12.798	3.403	EPSD	COSMIC	8.102	Loss
CMGC_MAPK_ERK1_MAPK1_ST	Q3V6T2	CCDC88A	P28482	MAPK1	T1739	V1735L	1735	Missense	distal	-4	no	12.798	12.848	EPSD	COSMIC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q3V6T2	CCDC88A	P28482	MAPK1	T1774	S1768C	1768	Missense	distal	-6	no	15.131	14.990	EPSD	COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q3V6T2	CCDC88A	P28482	MAPK1	T1774	P1775S	1775	Missense	proximal	1	no	15.131	5.736	EPSD	COSMIC	8.102	Loss
CMGC_MAPK_ERK1_MAPK1_ST	Q3V6T2	CCDC88A	P28482	MAPK1	T1774	I1781M	1781	Missense	distal	7	no	15.131	14.942	EPSD	COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q3V6T2	CCDC88A	P28482	MAPK1	T1774	S1769Y	1769	Missense	distal	-5	no	15.131	15.262	EPSD	COSMIC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q3V6T2	CCDC88A	P28482	MAPK1	T1774	G1776S	1776	Missense	proximal	2	no	15.131	15.084	EPSD	COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q3V6T2	CCDC88A	P28482	MAPK1	T1774	A1770T	1770	Missense	distal	-4	no	15.131	15.110	EPSD	COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q3V6T2	CCDC88A	P28482	MAPK1	T1774	P1773L	1773	Missense	proximal	-1	no	15.131	15.071	EPSD	COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q3V6T2	CCDC88A	P28482	MAPK1	T1774	P1773T	1773	Missense	proximal	-1	no	15.131	15.088	EPSD	COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q3V6T2	CCDC88A	P28482	MAPK1	T1774	A1770V	1770	Missense	distal	-4	no	15.131	15.070	EPSD	COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q3V6T2	CCDC88A	P28482	MAPK1	T1774	K1780E	1780	Missense	distal	6	no	15.131	15.107	EPSD	COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q3V6T2	CCDC88A	P28482	MAPK1	T1811	A1812V	1812	Missense	proximal	1	no	8.226	6.316	EPSD	COSMIC	8.102	Loss
CMGC_MAPK_ERK1_MAPK1_ST	Q3V6T2	CCDC88A	P28482	MAPK1	T1811	R1817K	1817	Missense	distal	6	no	8.226	8.390	EPSD	COSMIC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q3V6T2	CCDC88A	P28482	MAPK1	T1811	V1808M	1808	Missense	distal	-3	no	8.226	8.096	EPSD	COSMIC	8.102	Loss
CMGC_MAPK_ERK1_MAPK1_ST	Q3V6T2	CCDC88A	P28482	MAPK1	T1811	R1817Q	1817	Missense	distal	6	no	8.226	8.045	EPSD	COSMIC	8.102	Loss
CMGC_MAPK_ERK1_MAPK1_ST	Q3V6T2	CCDC88A	P28482	MAPK1	T1811	V1808L	1808	Missense	distal	-3	no	8.226	8.149	EPSD	COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q3V6T2	CCDC88A	P28482	MAPK1	T1811	T1815S	1815	Missense	distal	4	no	8.226	8.339	EPSD	COSMIC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q3V6T2	CCDC88A	P28482	MAPK1	T1811	R1804C	1804	Missense	distal	-7	no	8.226	8.194	EPSD	COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q3V6T2	CCDC88A	P28482	MAPK1	T1811	R1818K	1818	Missense	distal	7	no	8.226	8.171	EPSD	COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q3V6T2	CCDC88A	P28482	MAPK1	S1837	S1837Y	1837	Missense	central	0	yes	14.657	0.000	EPSD	COSMIC	8.102	Loss
CMGC_MAPK_ERK1_MAPK1_ST	Q3V6T2	CCDC88A	P28482	MAPK1	S1837	P1838A	1838	Missense	proximal	1	no	14.657	7.027	EPSD	COSMIC	8.102	Loss
CMGC_MAPK_ERK1_MAPK1_ST	Q3V6T2	CCDC88A	P28482	MAPK1	S1837	D1843Y	1843	Missense	distal	6	no	14.657	14.084	EPSD	COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q3V6T2	CCDC88A	P28482	MAPK1	S1837	V1835G	1835	Missense	proximal	-2	no	14.657	13.336	EPSD	COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q3V6T2	CCDC88A	P28482	MAPK1	S1837	P1839A	1839	Missense	proximal	2	no	14.657	14.528	EPSD	COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q3V6T2	CCDC88A	P28482	MAPK1	S1837	A1840V	1840	Missense	distal	3	no	14.657	14.637	EPSD	COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q9ULV5	HSF4	P28482	MAPK1	T221	S217R	217	Missense	distal	-4	no	14.068	14.063	EPSD	COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q9Y463	DYRK1B	P28482	MAPK1	S421	R419H	419	Missense	proximal	-2	no	12.419	11.482	PhosphoSitePlus	COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q9Y463	DYRK1B	P28482	MAPK1	S421	L423M	423	Missense	proximal	2	no	12.419	12.376	PhosphoSitePlus	COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q9Y463	DYRK1B	P28482	MAPK1	S421	A425S	425	Missense	distal	4	no	12.419	12.512	PhosphoSitePlus	COSMIC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q9Y463	DYRK1B	P28482	MAPK1	S421	L423Q	423	Missense	proximal	2	no	12.419	12.388	PhosphoSitePlus	COSMIC;CCLE	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q9Y463	DYRK1B	P28482	MAPK1	S421	P422H	422	Missense	proximal	1	no	12.419	4.595	PhosphoSitePlus	COSMIC	8.102	Loss
CMGC_MAPK_ERK1_MAPK1_ST	Q9Y463	DYRK1B	P28482	MAPK1	S421	A418T	418	Missense	distal	-3	no	12.419	12.577	PhosphoSitePlus	COSMIC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q9Y463	DYRK1B	P28482	MAPK1	S451	S449P	449	Missense	proximal	-2	no	14.029	16.863	EPSD	COSMIC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q9Y463	DYRK1B	P28482	MAPK1	S451	D456N	456	Missense	distal	5	no	14.029	13.931	EPSD	COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q9Y463	DYRK1B	P28482	MAPK1	S451	T457I	457	Missense	distal	6	no	14.029	13.573	EPSD	COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q9Y463	DYRK1B	P28482	MAPK1	S451	P452H	452	Missense	proximal	1	no	14.029	6.205	EPSD	COSMIC	8.102	Loss
CMGC_MAPK_ERK1_MAPK1_ST	Q9Y463	DYRK1B	P28482	MAPK1	S451	S446R	446	Missense	distal	-5	no	14.029	14.003	EPSD	COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q9Y463	DYRK1B	P28482	MAPK1	S554	P552L	552	Missense	proximal	-2	no	17.752	15.835	EPSD	COSMIC;GDSC;CCLE	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q9Y463	DYRK1B	P28482	MAPK1	S554	R551H	551	Missense	distal	-3	no	17.752	17.423	EPSD	COSMIC;GDSC;CCLE	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q9Y463	DYRK1B	P28482	MAPK1	S554	P561L	561	Missense	distal	7	no	17.752	18.052	EPSD	COSMIC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q9Y463	DYRK1B	P28482	MAPK1	S557	P552L	552	Missense	distal	-5	no	16.760	16.908	EPSD	COSMIC;GDSC;CCLE	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q9Y463	DYRK1B	P28482	MAPK1	S557	R551H	551	Missense	distal	-6	no	16.760	16.677	EPSD	COSMIC;GDSC;CCLE	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q9Y463	DYRK1B	P28482	MAPK1	S557	P561L	561	Missense	distal	4	no	16.760	16.639	EPSD	COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	C9JLW8	MCRIP1	P28482	MAPK1	S4	P5S	5	Missense	proximal	1	no	13.750	4.355	EPSD	COSMIC	8.102	Loss
CMGC_MAPK_ERK1_MAPK1_ST	C9JLW8	MCRIP1	P28482	MAPK1	S17	N12K	12	Missense	distal	-5	no	9.407	9.384	EPSD	COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	C9JLW8	MCRIP1	P28482	MAPK1	S17	T16K	16	Missense	proximal	-1	no	9.407	9.462	EPSD	COSMIC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	C9JLW8	MCRIP1	P28482	MAPK1	S18	N12K	12	Missense	distal	-6	no	16.651	16.659	EPSD	COSMIC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	C9JLW8	MCRIP1	P28482	MAPK1	S18	T16K	16	Missense	proximal	-2	no	16.651	16.931	EPSD	COSMIC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	C9JLW8	MCRIP1	P28482	MAPK1	S21	T16K	16	Missense	distal	-5	no	19.753	19.653	PhosphoSitePlus;EPSD	COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	C9JLW8	MCRIP1	P28482	MAPK1	T30	V37I	37	Missense	distal	7	no	17.060	17.325	EPSD;PhosphoSitePlus	COSMIC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	C9JLW8	MCRIP1	P28482	MAPK1	S74	K79R	79	Missense	distal	5	no	7.969	8.105	EPSD	COSMIC	8.102	Gain
CMGC_MAPK_ERK1_MAPK1_ST	Q8N122	RPTOR	P28482	MAPK1	S8	S3Y	3	Missense	distal	-5	no	13.924	14.055	EPSD;PhosphoSitePlus	COSMIC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q8N122	RPTOR	P28482	MAPK1	S696	E689K	689	Missense	distal	-7	no	14.063	14.056	PhosphoSitePlus;EPSD	COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q8N122	RPTOR	P28482	MAPK1	S696	S696Y	696	Missense	central	0	yes	14.063	0.000	PhosphoSitePlus;EPSD	COSMIC	8.102	Loss
CMGC_MAPK_ERK1_MAPK1_ST	Q8N122	RPTOR	P28482	MAPK1	S696	A693T	693	Missense	distal	-3	no	14.063	14.220	PhosphoSitePlus;EPSD	COSMIC;GDSC;CCLE	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q8N122	RPTOR	P28482	MAPK1	S696	G702E	702	Missense	distal	6	no	14.063	14.174	PhosphoSitePlus;EPSD	COSMIC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q8N122	RPTOR	P28482	MAPK1	S696	S696A	696	Missense	central	0	yes	14.063	0.000	PhosphoSitePlus;EPSD	COSMIC	8.102	Loss
CMGC_MAPK_ERK1_MAPK1_ST	Q8N122	RPTOR	P28482	MAPK1	T699	S696Y	696	Missense	distal	-3	no	8.654	8.385	EPSD	COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q8N122	RPTOR	P28482	MAPK1	T699	A693T	693	Missense	distal	-6	no	8.654	8.644	EPSD	COSMIC;GDSC;CCLE	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q8N122	RPTOR	P28482	MAPK1	T699	G702E	702	Missense	distal	3	no	8.654	8.562	EPSD	COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q8N122	RPTOR	P28482	MAPK1	T699	S696A	696	Missense	distal	-3	no	8.654	8.464	EPSD	COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q8N122	RPTOR	P28482	MAPK1	T706	P712L	712	Missense	distal	6	no	13.957	13.550	EPSD	COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q8N122	RPTOR	P28482	MAPK1	T706	D710N	710	Missense	distal	4	no	13.957	14.016	EPSD	COSMIC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q8N122	RPTOR	P28482	MAPK1	T706	R709G	709	Missense	distal	3	no	13.957	13.995	EPSD	COSMIC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q8N122	RPTOR	P28482	MAPK1	T706	G702E	702	Missense	distal	-4	no	13.957	14.278	EPSD	COSMIC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q8N122	RPTOR	P28482	MAPK1	S711	R718C	718	Missense	distal	7	no	15.912	16.568	EPSD	COSMIC;CCLE	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q8N122	RPTOR	P28482	MAPK1	S711	P712L	712	Missense	proximal	1	no	15.912	7.103	EPSD	COSMIC	8.102	Loss
CMGC_MAPK_ERK1_MAPK1_ST	Q8N122	RPTOR	P28482	MAPK1	S711	P715S	715	Missense	distal	4	no	15.912	15.902	EPSD	COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q8N122	RPTOR	P28482	MAPK1	S711	D710N	710	Missense	proximal	-1	no	15.912	15.974	EPSD	COSMIC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q8N122	RPTOR	P28482	MAPK1	S711	R709G	709	Missense	proximal	-2	no	15.912	14.537	EPSD	COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q8N122	RPTOR	P28482	MAPK1	T714	R718C	718	Missense	distal	4	no	16.181	15.922	EPSD	COSMIC;CCLE	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q8N122	RPTOR	P28482	MAPK1	T714	P712L	712	Missense	proximal	-2	no	16.181	14.264	EPSD	COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q8N122	RPTOR	P28482	MAPK1	T714	P715S	715	Missense	proximal	1	no	16.181	6.786	EPSD	COSMIC	8.102	Loss
CMGC_MAPK_ERK1_MAPK1_ST	Q8N122	RPTOR	P28482	MAPK1	T714	D710N	710	Missense	distal	-4	no	16.181	16.153	EPSD	COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q8N122	RPTOR	P28482	MAPK1	T714	S719Y	719	Missense	distal	5	no	16.181	15.892	EPSD	COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q8N122	RPTOR	P28482	MAPK1	T714	S721N	721	Missense	distal	7	no	16.181	16.164	EPSD	COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q8N122	RPTOR	P28482	MAPK1	T714	V720L	720	Missense	distal	6	no	16.181	15.989	EPSD	COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q8N122	RPTOR	P28482	MAPK1	T714	R709G	709	Missense	distal	-5	no	16.181	16.201	EPSD	COSMIC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q8N122	RPTOR	P28482	MAPK1	S722	R718C	718	Missense	distal	-4	no	8.137	7.499	EPSD	COSMIC;CCLE	8.102	Loss
CMGC_MAPK_ERK1_MAPK1_ST	Q8N122	RPTOR	P28482	MAPK1	S722	P715S	715	Missense	distal	-7	no	8.137	8.133	EPSD	COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q8N122	RPTOR	P28482	MAPK1	S722	S719Y	719	Missense	distal	-3	no	8.137	7.868	EPSD	COSMIC	8.102	Loss
CMGC_MAPK_ERK1_MAPK1_ST	Q8N122	RPTOR	P28482	MAPK1	S722	S721N	721	Missense	proximal	-1	no	8.137	8.186	EPSD	COSMIC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q8N122	RPTOR	P28482	MAPK1	S722	V720L	720	Missense	proximal	-2	no	8.137	8.092	EPSD	COSMIC	8.102	Loss
CMGC_MAPK_ERK1_MAPK1_ST	Q8N122	RPTOR	P28482	MAPK1	T731	S738Y	738	Missense	distal	7	no	7.974	8.491	EPSD	COSMIC	8.102	Gain
CMGC_MAPK_ERK1_MAPK1_ST	Q8N122	RPTOR	P28482	MAPK1	S771	A765T	765	Missense	distal	-6	no	14.514	14.503	EPSD	COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q8N122	RPTOR	P28482	MAPK1	S771	E775Q	775	Missense	distal	4	no	14.514	14.443	EPSD	COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q8N122	RPTOR	P28482	MAPK1	S771	S766T	766	Missense	distal	-5	no	14.514	14.542	EPSD	COSMIC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q8N122	RPTOR	P28482	MAPK1	S863	K867R	867	Missense	distal	4	no	15.667	15.657	EPSD;PhosphoSitePlus	COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q8N122	RPTOR	P28482	MAPK1	S863	G868S	868	Missense	distal	5	no	15.667	15.687	EPSD;PhosphoSitePlus	COSMIC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q8N122	RPTOR	P28482	MAPK1	S863	P861L	861	Missense	proximal	-2	no	15.667	13.750	EPSD;PhosphoSitePlus	COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q8N122	RPTOR	P28482	MAPK1	S863	V869M	869	Missense	distal	6	no	15.667	15.449	EPSD;PhosphoSitePlus	COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q8N122	RPTOR	P28482	MAPK1	S863	A862T	862	Missense	proximal	-1	no	15.667	15.662	EPSD;PhosphoSitePlus	COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q8N122	RPTOR	P28482	MAPK1	S877	A874V	874	Missense	distal	-3	no	14.703	14.763	EPSD	COSMIC;GDSC;CCLE	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q8N122	RPTOR	P28482	MAPK1	S877	P878S	878	Missense	proximal	1	no	14.703	5.308	EPSD	COSMIC	8.102	Loss
CMGC_MAPK_ERK1_MAPK1_ST	Q8N122	RPTOR	P28482	MAPK1	S877	P879S	879	Missense	proximal	2	no	14.703	14.675	EPSD	COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q8N122	RPTOR	P28482	MAPK1	S877	A880S	880	Missense	distal	3	no	14.703	14.694	EPSD	COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q8N122	RPTOR	P28482	MAPK1	S877	P878L	878	Missense	proximal	1	no	14.703	5.893	EPSD	COSMIC	8.102	Loss
CMGC_MAPK_ERK1_MAPK1_ST	Q8N122	RPTOR	P28482	MAPK1	S881	A874V	874	Missense	distal	-7	no	8.691	8.674	EPSD	COSMIC;GDSC;CCLE	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q8N122	RPTOR	P28482	MAPK1	S881	P878S	878	Missense	distal	-3	no	8.691	8.514	EPSD	COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q8N122	RPTOR	P28482	MAPK1	S881	P879S	879	Missense	proximal	-2	no	8.691	5.856	EPSD	COSMIC	8.102	Loss
CMGC_MAPK_ERK1_MAPK1_ST	Q8N122	RPTOR	P28482	MAPK1	S881	A880S	880	Missense	proximal	-1	no	8.691	8.684	EPSD	COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q8N122	RPTOR	P28482	MAPK1	S881	P878L	878	Missense	distal	-3	no	8.691	8.307	EPSD	COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q8N122	RPTOR	P28482	MAPK1	T908	R905L	905	Missense	distal	-3	no	8.227	7.863	EPSD	COSMIC	8.102	Loss
CMGC_MAPK_ERK1_MAPK1_ST	Q8N122	RPTOR	P28482	MAPK1	T908	P911L	911	Missense	distal	3	no	8.227	8.316	EPSD	COSMIC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q8N122	RPTOR	P28482	MAPK1	T908	P906Q	906	Missense	proximal	-2	no	8.227	5.233	EPSD	COSMIC	8.102	Loss
CMGC_MAPK_ERK1_MAPK1_ST	Q8N122	RPTOR	P28482	MAPK1	T908	R905W	905	Missense	distal	-3	no	8.227	7.528	EPSD	COSMIC	8.102	Loss
CMGC_MAPK_ERK1_MAPK1_ST	Q8N122	RPTOR	P28482	MAPK1	T908	G910D	910	Missense	proximal	2	no	8.227	8.192	EPSD	COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q8N122	RPTOR	P28482	MAPK1	T917	P924T	924	Missense	distal	7	no	11.419	11.582	EPSD	COSMIC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q8N122	RPTOR	P28482	MAPK1	T917	Y916C	916	Missense	proximal	-1	no	11.419	11.373	EPSD	COSMIC;GDSC;CCLE	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q8N122	RPTOR	P28482	MAPK1	T917	P911L	911	Missense	distal	-6	no	11.419	11.328	EPSD	COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q8N122	RPTOR	P28482	MAPK1	T917	G910D	910	Missense	distal	-7	no	11.419	11.435	EPSD	COSMIC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q8N122	RPTOR	P28482	MAPK1	T917	Q922R	922	Missense	distal	5	no	11.419	11.590	EPSD	COSMIC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q8N122	RPTOR	P28482	MAPK1	S920	P924T	924	Missense	distal	4	no	8.381	8.257	EPSD	COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q8N122	RPTOR	P28482	MAPK1	S920	R925W	925	Missense	distal	5	no	8.381	7.852	EPSD	COSMIC	8.102	Loss
CMGC_MAPK_ERK1_MAPK1_ST	Q8N122	RPTOR	P28482	MAPK1	S920	Y916C	916	Missense	distal	-4	no	8.381	8.326	EPSD	COSMIC;GDSC;CCLE	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q8N122	RPTOR	P28482	MAPK1	S920	R925Q	925	Missense	distal	5	no	8.381	8.211	EPSD	COSMIC;CCLE	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q8N122	RPTOR	P28482	MAPK1	S920	R927Q	927	Missense	distal	7	no	8.381	8.496	EPSD	COSMIC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q8N122	RPTOR	P28482	MAPK1	S920	R927W	927	Missense	distal	7	no	8.381	9.353	EPSD	COSMIC;CCLE	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q8N122	RPTOR	P28482	MAPK1	S920	Q922R	922	Missense	proximal	2	no	8.381	8.672	EPSD	COSMIC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P49407	ARRB1	P28482	MAPK1	S412	G411S	411	Missense	proximal	-1	no	17.031	17.042	PhosphoSitePlus	COSMIC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q53EZ4	CEP55	P28482	MAPK1	S425	A424T	424	Missense	proximal	-1	no	14.555	14.550	PhosphoSitePlus;EPSD	COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q53EZ4	CEP55	P28482	MAPK1	S428	L433P	433	Missense	distal	5	no	16.148	16.362	EPSD;PhosphoSitePlus	COSMIC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q53EZ4	CEP55	P28482	MAPK1	S428	E435G	435	Missense	distal	7	no	16.148	16.276	EPSD;PhosphoSitePlus	COSMIC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q53EZ4	CEP55	P28482	MAPK1	S428	A424T	424	Missense	distal	-4	no	16.148	16.128	EPSD;PhosphoSitePlus	COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P31645	SLC6A4	P28482	MAPK1	S52	Y47C	47	Missense	distal	-5	no	16.017	16.089	EPSD	COSMIC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P31645	SLC6A4	P28482	MAPK1	S52	G56E	56	Missense	distal	4	no	16.017	16.039	EPSD	COSMIC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P31645	SLC6A4	P28482	MAPK1	T616	G623R	623	Missense	distal	7	no	18.535	18.470	PhosphoSitePlus	COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P33076	CIITA	P28482	MAPK1	S280	G276D	276	Missense	distal	-4	no	16.876	17.212	PhosphoSitePlus;EPSD	COSMIC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P33076	CIITA	P28482	MAPK1	S280	G276V	276	Missense	distal	-4	no	16.876	16.872	PhosphoSitePlus;EPSD	COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P33076	CIITA	P28482	MAPK1	S280	P281L	281	Missense	proximal	1	no	16.876	8.067	PhosphoSitePlus;EPSD	COSMIC	8.102	Loss
CMGC_MAPK_ERK1_MAPK1_ST	P33076	CIITA	P28482	MAPK1	S280	S286F	286	Missense	distal	6	no	16.876	16.436	PhosphoSitePlus;EPSD	COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P33076	CIITA	P28482	MAPK1	S280	S280Y	280	Missense	central	0	yes	16.876	0.000	PhosphoSitePlus;EPSD	COSMIC	8.102	Loss
CMGC_MAPK_ERK1_MAPK1_ST	P33076	CIITA	P28482	MAPK1	S280	G276S	276	Missense	distal	-4	no	16.876	17.142	PhosphoSitePlus;EPSD	COSMIC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P33076	CIITA	P28482	MAPK1	S288	A291S	291	Missense	distal	3	no	12.958	12.949	EPSD;PhosphoSitePlus	COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P33076	CIITA	P28482	MAPK1	S288	P281L	281	Missense	distal	-7	no	12.958	12.946	EPSD;PhosphoSitePlus	COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P33076	CIITA	P28482	MAPK1	S288	S286F	286	Missense	proximal	-2	no	12.958	13.152	EPSD;PhosphoSitePlus	COSMIC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P33076	CIITA	P28482	MAPK1	S288	P289L	289	Missense	proximal	1	no	12.958	4.148	EPSD;PhosphoSitePlus	COSMIC	8.102	Loss
CMGC_MAPK_ERK1_MAPK1_ST	P33076	CIITA	P28482	MAPK1	T740	R742K	742	Missense	proximal	2	no	14.428	14.247	EPSD	COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P33076	CIITA	P28482	MAPK1	T740	L739F	739	Missense	proximal	-1	no	14.428	14.398	EPSD	COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P33076	CIITA	P28482	MAPK1	T740	L733P	733	Missense	distal	-7	no	14.428	14.440	EPSD	COSMIC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P33076	CIITA	P28482	MAPK1	T740	P734R	734	Missense	distal	-6	no	14.428	14.436	EPSD	COSMIC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P33076	CIITA	P28482	MAPK1	T740	R745K	745	Missense	distal	5	no	14.428	14.293	EPSD	COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P33076	CIITA	P28482	MAPK1	S834	R832C	832	Missense	proximal	-2	no	8.103	6.155	EPSD	COSMIC	8.102	Loss
CMGC_MAPK_ERK1_MAPK1_ST	P33076	CIITA	P28482	MAPK1	S834	G831D	831	Missense	distal	-3	no	8.103	8.163	EPSD	COSMIC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P78347	GTF2I	P28482	MAPK1	S181	G179R	179	Missense	proximal	-2	no	7.999	9.375	EPSD	COSMIC	8.102	Gain
CMGC_MAPK_ERK1_MAPK1_ST	P78347	GTF2I	P28482	MAPK1	T202	M200V	200	Missense	proximal	-2	no	5.962	8.104	EPSD	COSMIC	8.102	Gain
CMGC_MAPK_ERK1_MAPK1_ST	P78347	GTF2I	P28482	MAPK1	S210	G213E	213	Missense	distal	3	no	15.139	15.046	EPSD	COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P78347	GTF2I	P28482	MAPK1	S210	S214N	214	Missense	distal	4	no	15.139	15.102	EPSD	COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P78347	GTF2I	P28482	MAPK1	T413	R410C	410	Missense	distal	-3	no	10.176	9.492	EPSD	COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P78347	GTF2I	P28482	MAPK1	T413	L419M	419	Missense	distal	6	no	10.176	10.149	EPSD	COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P78347	GTF2I	P28482	MAPK1	T413	S412L	412	Missense	proximal	-1	no	10.176	10.159	EPSD	COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P78347	GTF2I	P28482	MAPK1	S515	R514I	514	Missense	proximal	-1	no	11.388	11.341	EPSD	COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P78347	GTF2I	P28482	MAPK1	T558	P559L	559	Missense	proximal	1	no	12.836	4.026	EPSD	COSMIC	8.102	Loss
CMGC_MAPK_ERK1_MAPK1_ST	P78347	GTF2I	P28482	MAPK1	S620	T622A	622	Missense	proximal	2	no	11.425	11.346	EPSD	COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P78347	GTF2I	P28482	MAPK1	S668	S668P	668	Missense	central	0	yes	14.732	0.000	EPSD	COSMIC	8.102	Loss
CMGC_MAPK_ERK1_MAPK1_ST	P78347	GTF2I	P28482	MAPK1	S674	S668P	668	Missense	distal	-6	no	17.993	18.019	EPSD	COSMIC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P78347	GTF2I	P28482	MAPK1	T703	T707I	707	Missense	distal	4	no	14.801	14.748	EPSD	COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q14790	CASP8	P28482	MAPK1	S16	S21F	21	Missense	distal	5	no	8.781	8.584	EPSD	COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q14790	CASP8	P28482	MAPK1	S16	K23E	23	Missense	distal	7	no	8.781	8.774	EPSD	COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q14790	CASP8	P28482	MAPK1	S16	D9N	9	Missense	distal	-7	no	8.781	8.782	EPSD	COSMIC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q14790	CASP8	P28482	MAPK1	S16	D18H	18	Missense	proximal	2	no	8.781	8.667	EPSD	COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q14790	CASP8	P28482	MAPK1	S60	K63T	63	Missense	distal	3	no	8.126	8.190	EPSD	COSMIC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q14790	CASP8	P28482	MAPK1	S60	S60F	60	Missense	central	0	yes	8.126	0.000	EPSD	COSMIC	8.102	Loss
CMGC_MAPK_ERK1_MAPK1_ST	Q14790	CASP8	P28482	MAPK1	S60	L54S	54	Missense	distal	-6	no	8.126	8.191	EPSD	COSMIC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q14790	CASP8	P28482	MAPK1	S60	L65R	65	Missense	distal	5	no	8.126	8.388	EPSD	COSMIC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q14790	CASP8	P28482	MAPK1	S60	L66H	66	Missense	distal	6	no	8.126	8.227	EPSD	COSMIC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q14790	CASP8	P28482	MAPK1	S192	S186N	186	Missense	distal	-6	no	15.353	15.356	EPSD	COSMIC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q14790	CASP8	P28482	MAPK1	S192	S188A	188	Missense	distal	-4	no	15.353	15.144	EPSD	COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q14790	CASP8	P28482	MAPK1	S211	S211L	211	Missense	central	0	yes	14.927	0.000	EPSD	COSMIC	8.102	Loss
CMGC_MAPK_ERK1_MAPK1_ST	Q14790	CASP8	P28482	MAPK1	S211	V205I	205	Missense	distal	-6	no	14.927	14.886	EPSD	COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q14790	CASP8	P28482	MAPK1	S211	S209L	209	Missense	proximal	-2	no	14.927	15.844	EPSD	COSMIC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q14790	CASP8	P28482	MAPK1	S211	T207I	207	Missense	distal	-4	no	14.927	14.570	EPSD	COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q14790	CASP8	P28482	MAPK1	S211	S211C	211	Missense	central	0	yes	14.927	0.000	EPSD	COSMIC	8.102	Loss
CMGC_MAPK_ERK1_MAPK1_ST	Q14790	CASP8	P28482	MAPK1	S211	D216G	216	Missense	distal	5	no	14.927	14.883	EPSD	COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q14790	CASP8	P28482	MAPK1	S211	P212L	212	Missense	proximal	1	no	14.927	6.117	EPSD	COSMIC	8.102	Loss
CMGC_MAPK_ERK1_MAPK1_ST	Q14790	CASP8	P28482	MAPK1	S211	P212T	212	Missense	proximal	1	no	14.927	6.428	EPSD	COSMIC	8.102	Loss
CMGC_MAPK_ERK1_MAPK1_ST	Q14790	CASP8	P28482	MAPK1	S211	P212A	212	Missense	proximal	1	no	14.927	7.297	EPSD	COSMIC	8.102	Loss
CMGC_MAPK_ERK1_MAPK1_ST	Q14790	CASP8	P28482	MAPK1	S211	R213S	213	Missense	proximal	2	no	14.927	14.786	EPSD	COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q14790	CASP8	P28482	MAPK1	T221	L222P	222	Missense	proximal	1	no	6.119	14.928	EPSD	COSMIC	8.102	Gain
CMGC_MAPK_ERK1_MAPK1_ST	Q14790	CASP8	P28482	MAPK1	T263	H264Y	264	Missense	proximal	1	no	7.289	8.104	EPSD	COSMIC	8.102	Gain
CMGC_MAPK_ERK1_MAPK1_ST	Q14790	CASP8	P28482	MAPK1	T373	P379L	379	Missense	distal	6	no	8.624	8.217	EPSD	COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q14790	CASP8	P28482	MAPK1	T373	P379Q	379	Missense	distal	6	no	8.624	8.336	EPSD	COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q14790	CASP8	P28482	MAPK1	T373	P379T	379	Missense	distal	6	no	8.624	8.414	EPSD	COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q14790	CASP8	P28482	MAPK1	T373	S375L	375	Missense	proximal	2	no	8.624	8.504	EPSD	COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q14790	CASP8	P28482	MAPK1	T373	Q366H	366	Missense	distal	-7	no	8.624	8.605	EPSD	COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q14790	CASP8	P28482	MAPK1	T373	E376V	376	Missense	distal	3	no	8.624	8.690	EPSD	COSMIC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q14790	CASP8	P28482	MAPK1	T373	E372D	372	Missense	proximal	-1	no	8.624	8.583	EPSD	COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q14790	CASP8	P28482	MAPK1	S387	L385P	385	Missense	proximal	-2	no	14.713	16.630	PhosphoSitePlus	COSMIC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q14790	CASP8	P28482	MAPK1	S387	T390I	390	Missense	distal	3	no	14.713	14.778	PhosphoSitePlus	COSMIC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q14790	CASP8	P28482	MAPK1	S387	P394L	394	Missense	distal	7	no	14.713	15.012	PhosphoSitePlus	COSMIC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q14790	CASP8	P28482	MAPK1	S387	D384N	384	Missense	distal	-3	no	14.713	14.680	PhosphoSitePlus	COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q14790	CASP8	P28482	MAPK1	S387	P388S	388	Missense	proximal	1	no	14.713	5.318	PhosphoSitePlus	COSMIC;CCLE	8.102	Loss
CMGC_MAPK_ERK1_MAPK1_ST	Q14790	CASP8	P28482	MAPK1	S387	P394S	394	Missense	distal	7	no	14.713	14.724	PhosphoSitePlus	COSMIC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q14790	CASP8	P28482	MAPK1	S387	R391G	391	Missense	distal	4	no	14.713	14.686	PhosphoSitePlus	COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q14790	CASP8	P28482	MAPK1	S387	P394Q	394	Missense	distal	7	no	14.713	14.842	PhosphoSitePlus	COSMIC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q14790	CASP8	P28482	MAPK1	S387	T390M	390	Missense	distal	3	no	14.713	14.736	PhosphoSitePlus	COSMIC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q14790	CASP8	P28482	MAPK1	S387	P388L	388	Missense	proximal	1	no	14.713	5.903	PhosphoSitePlus	COSMIC	8.102	Loss
CMGC_MAPK_ERK1_MAPK1_ST	Q14790	CASP8	P28482	MAPK1	S387	S386L	386	Missense	proximal	-1	no	14.713	14.696	PhosphoSitePlus	COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q14790	CASP8	P28482	MAPK1	S387	P394T	394	Missense	distal	7	no	14.713	14.876	PhosphoSitePlus	COSMIC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q14790	CASP8	P28482	MAPK1	T390	D395E	395	Missense	distal	5	no	8.921	8.852	EPSD	COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q14790	CASP8	P28482	MAPK1	T390	L385P	385	Missense	distal	-5	no	8.921	8.773	EPSD	COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q14790	CASP8	P28482	MAPK1	T390	T390I	390	Missense	central	0	yes	8.921	0.000	EPSD	COSMIC	8.102	Loss
CMGC_MAPK_ERK1_MAPK1_ST	Q14790	CASP8	P28482	MAPK1	T390	P394L	394	Missense	distal	4	no	8.921	8.801	EPSD	COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q14790	CASP8	P28482	MAPK1	T390	D384N	384	Missense	distal	-6	no	8.921	8.876	EPSD	COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q14790	CASP8	P28482	MAPK1	T390	P388S	388	Missense	proximal	-2	no	8.921	6.087	EPSD	COSMIC;CCLE	8.102	Loss
CMGC_MAPK_ERK1_MAPK1_ST	Q14790	CASP8	P28482	MAPK1	T390	P394S	394	Missense	distal	4	no	8.921	8.911	EPSD	COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q14790	CASP8	P28482	MAPK1	T390	R391G	391	Missense	proximal	1	no	8.921	8.510	EPSD	COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q14790	CASP8	P28482	MAPK1	T390	D395N	395	Missense	distal	5	no	8.921	8.823	EPSD	COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q14790	CASP8	P28482	MAPK1	T390	P394Q	394	Missense	distal	4	no	8.921	8.813	EPSD	COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q14790	CASP8	P28482	MAPK1	T390	T390M	390	Missense	central	0	yes	8.921	0.000	EPSD	COSMIC	8.102	Loss
CMGC_MAPK_ERK1_MAPK1_ST	Q14790	CASP8	P28482	MAPK1	T390	P388L	388	Missense	proximal	-2	no	8.921	7.004	EPSD	COSMIC	8.102	Loss
CMGC_MAPK_ERK1_MAPK1_ST	Q14790	CASP8	P28482	MAPK1	T390	S386L	386	Missense	distal	-4	no	8.921	8.701	EPSD	COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q14790	CASP8	P28482	MAPK1	T390	P394T	394	Missense	distal	4	no	8.921	8.798	EPSD	COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P28482	MAPK1	P28482	MAPK1	S29	P23S	23	Missense	distal	-6	no	8.276	8.250	EPSD	COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P28482	MAPK1	P28482	MAPK1	S29	E33Q	33	Missense	distal	4	no	8.276	8.205	EPSD	COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P28482	MAPK1	P28482	MAPK1	S29	G34D	34	Missense	distal	5	no	8.276	8.320	EPSD	COSMIC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P28482	MAPK1	P28482	MAPK1	S29	I31M	31	Missense	proximal	2	no	8.276	8.256	EPSD	COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P28482	MAPK1	P28482	MAPK1	S142	R148S	148	Missense	distal	6	no	8.024	8.131	EPSD	COSMIC	8.102	Gain
CMGC_MAPK_ERK1_MAPK1_ST	P28482	MAPK1	P28482	MAPK1	T185	F183S	183	Missense	proximal	-2	no	8.330	8.137	EPSD	COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P28482	MAPK1	P28482	MAPK1	S246	S246F	246	Missense	central	0	yes	15.872	0.000	PhosphoSitePlus	COSMIC	8.102	Loss
CMGC_MAPK_ERK1_MAPK1_ST	P28482	MAPK1	P28482	MAPK1	S246	L244I	244	Missense	proximal	-2	no	15.872	15.894	PhosphoSitePlus	COSMIC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P37231	PPARG	P28482	MAPK1	S112	V108A	108	Missense	distal	-4	no	18.041	18.101	PhosphoSitePlus	COSMIC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P37231	PPARG	P28482	MAPK1	S273	D271E	271	Missense	proximal	-2	no	11.631	12.553	EPSD	COSMIC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	O43521	BCL2L11	P28482	MAPK1	S59	P60S	60	Missense	proximal	1	no	13.276	3.881	EPSD	COSMIC	8.102	Loss
CMGC_MAPK_ERK1_MAPK1_ST	O43521	BCL2L11	P28482	MAPK1	S59	P66S	66	Missense	distal	7	no	13.276	13.286	EPSD	COSMIC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	O43521	BCL2L11	P28482	MAPK1	S59	G58S	58	Missense	proximal	-1	no	13.276	13.287	EPSD	COSMIC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	O43521	BCL2L11	P28482	MAPK1	S69	P66S	66	Missense	distal	-3	no	15.383	15.207	PhosphoSitePlus	COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	O43521	BCL2L11	P28482	MAPK1	S69	A74V	74	Missense	distal	5	no	15.383	15.400	PhosphoSitePlus	COSMIC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	O43521	BCL2L11	P28482	MAPK1	S69	P72S	72	Missense	distal	3	no	15.383	15.452	PhosphoSitePlus	COSMIC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	O43521	BCL2L11	P28482	MAPK1	S69	R76K	76	Missense	distal	7	no	15.383	15.328	PhosphoSitePlus	COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	O43521	BCL2L11	P28482	MAPK1	S69	R76S	76	Missense	distal	7	no	15.383	15.380	PhosphoSitePlus	COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	O43521	BCL2L11	P28482	MAPK1	S77	P78S	78	Missense	proximal	1	no	14.223	4.828	EPSD	COSMIC	8.102	Loss
CMGC_MAPK_ERK1_MAPK1_ST	O43521	BCL2L11	P28482	MAPK1	S77	A74V	74	Missense	distal	-3	no	14.223	14.283	EPSD	COSMIC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	O43521	BCL2L11	P28482	MAPK1	S77	P72S	72	Missense	distal	-5	no	14.223	14.297	EPSD	COSMIC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	O43521	BCL2L11	P28482	MAPK1	S77	R76K	76	Missense	proximal	-1	no	14.223	14.255	EPSD	COSMIC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	O43521	BCL2L11	P28482	MAPK1	S77	R84K	84	Missense	distal	7	no	14.223	14.168	EPSD	COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	O43521	BCL2L11	P28482	MAPK1	S77	R76S	76	Missense	proximal	-1	no	14.223	14.199	EPSD	COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	O43521	BCL2L11	P28482	MAPK1	S77	P78L	78	Missense	proximal	1	no	14.223	5.413	EPSD	COSMIC;GDSC;CCLE	8.102	Loss
CMGC_MAPK_ERK1_MAPK1_ST	O43521	BCL2L11	P28482	MAPK1	S98	S104R	104	Missense	distal	6	no	8.256	8.149	EPSD	COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	O43521	BCL2L11	P28482	MAPK1	S98	F97L	97	Missense	proximal	-1	no	8.256	8.286	EPSD	COSMIC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	O43521	BCL2L11	P28482	MAPK1	S98	D100G	100	Missense	proximal	2	no	8.256	8.291	EPSD	COSMIC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	O43521	BCL2L11	P28482	MAPK1	S98	S93F	93	Missense	distal	-5	no	8.256	8.345	EPSD	COSMIC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	O43521	BCL2L11	P28482	MAPK1	S98	S94T	94	Missense	distal	-4	no	8.256	8.027	EPSD	COSMIC	8.102	Loss
CMGC_MAPK_ERK1_MAPK1_ST	O43521	BCL2L11	P28482	MAPK1	S104	A106S	106	Missense	proximal	2	no	12.277	12.379	EPSD	COSMIC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	O43521	BCL2L11	P28482	MAPK1	S104	S104R	104	Missense	central	0	yes	12.277	0.000	EPSD	COSMIC	8.102	Loss
CMGC_MAPK_ERK1_MAPK1_ST	O43521	BCL2L11	P28482	MAPK1	S104	F97L	97	Missense	distal	-7	no	12.277	12.290	EPSD	COSMIC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	O43521	BCL2L11	P28482	MAPK1	S104	D100G	100	Missense	distal	-4	no	12.277	11.942	EPSD	COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	O43521	BCL2L11	P28482	MAPK1	T116	P120S	120	Missense	distal	4	no	15.649	15.638	EPSD	COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	O43521	BCL2L11	P28482	MAPK1	S118	P120S	120	Missense	proximal	2	no	14.907	14.880	EPSD	COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P35398	RORA	P28482	MAPK1	S49	S51F	51	Missense	proximal	2	no	10.233	10.101	EPSD	COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P35398	RORA	P28482	MAPK1	S49	R55K	55	Missense	distal	6	no	10.233	10.397	EPSD	COSMIC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P35398	RORA	P28482	MAPK1	S49	S54R	54	Missense	distal	5	no	10.233	10.265	EPSD	COSMIC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P35398	RORA	P28482	MAPK1	T183	N187S	187	Missense	distal	4	no	15.772	15.809	EPSD	COSMIC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P35398	RORA	P28482	MAPK1	T183	S189L	189	Missense	distal	6	no	15.772	15.365	EPSD	COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P35398	RORA	P28482	MAPK1	T183	P181L	181	Missense	proximal	-2	no	15.772	13.854	EPSD	COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P35398	RORA	P28482	MAPK1	T183	P184R	184	Missense	proximal	1	no	15.772	6.117	EPSD	COSMIC	8.102	Loss
CMGC_MAPK_ERK1_MAPK1_ST	Q9ULC4	MCTS1	P28482	MAPK1	S118	P114S	114	Missense	distal	-4	no	13.945	13.861	EPSD	COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P42229	STAT5A	P28482	MAPK1	S128	P129L	129	Missense	proximal	1	no	13.396	4.587	EPSD	COSMIC	8.102	Loss
CMGC_MAPK_ERK1_MAPK1_ST	P42229	STAT5A	P28482	MAPK1	S128	D135H	135	Missense	distal	7	no	13.396	13.623	EPSD	COSMIC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P42229	STAT5A	P28482	MAPK1	S128	S128F	128	Missense	central	0	yes	13.396	0.000	EPSD	COSMIC	8.102	Loss
CMGC_MAPK_ERK1_MAPK1_ST	P42229	STAT5A	P28482	MAPK1	S193	A187G	187	Missense	distal	-6	no	13.717	13.713	EPSD	COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P42229	STAT5A	P28482	MAPK1	S193	R200W	200	Missense	distal	7	no	13.717	14.688	EPSD	COSMIC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P42229	STAT5A	P28482	MAPK1	S193	Q188P	188	Missense	distal	-5	no	13.717	13.592	EPSD	COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P42229	STAT5A	P28482	MAPK1	S193	R200L	200	Missense	distal	7	no	13.717	14.002	EPSD	COSMIC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P42229	STAT5A	P28482	MAPK1	S193	S193R	193	Missense	central	0	yes	13.717	0.000	EPSD	COSMIC	8.102	Loss
CMGC_MAPK_ERK1_MAPK1_ST	P42229	STAT5A	P28482	MAPK1	S726	P725L	725	Missense	proximal	-1	no	12.425	12.365	EPSD	COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P42229	STAT5A	P28482	MAPK1	S726	P731T	731	Missense	distal	5	no	12.425	12.369	EPSD	COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P42229	STAT5A	P28482	MAPK1	S726	P725H	725	Missense	proximal	-1	no	12.425	12.382	EPSD	COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P42229	STAT5A	P28482	MAPK1	S726	D722N	722	Missense	distal	-4	no	12.425	12.397	EPSD	COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P42229	STAT5A	P28482	MAPK1	S780	R778C	778	Missense	proximal	-2	no	19.102	17.154	PhosphoSitePlus	COSMIC;CCLE	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P42229	STAT5A	P28482	MAPK1	S780	S780L	780	Missense	central	0	yes	19.102	0.000	PhosphoSitePlus	COSMIC	8.102	Loss
CMGC_MAPK_ERK1_MAPK1_ST	P42229	STAT5A	P28482	MAPK1	S780	S774T	774	Missense	distal	-6	no	19.102	19.078	PhosphoSitePlus	COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P42229	STAT5A	P28482	MAPK1	S780	S777Y	777	Missense	distal	-3	no	19.102	18.833	PhosphoSitePlus	COSMIC;GDSC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q15366	PCBP2	P28482	MAPK1	S173	P174S	174	Missense	proximal	1	no	13.695	4.300	EPSD;PhosphoSitePlus	COSMIC	8.102	Loss
CMGC_MAPK_ERK1_MAPK1_ST	Q15366	PCBP2	P28482	MAPK1	S173	M166V	166	Missense	distal	-7	no	13.695	13.697	EPSD;PhosphoSitePlus	COSMIC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q15366	PCBP2	P28482	MAPK1	S173	V178A	178	Missense	distal	5	no	13.695	13.678	EPSD;PhosphoSitePlus	COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q15366	PCBP2	P28482	MAPK1	S173	V178M	178	Missense	distal	5	no	13.695	13.633	EPSD;PhosphoSitePlus	COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q15366	PCBP2	P28482	MAPK1	S188	P186L	186	Missense	proximal	-2	no	8.253	6.335	EPSD	COSMIC	8.102	Loss
CMGC_MAPK_ERK1_MAPK1_ST	Q15366	PCBP2	P28482	MAPK1	S189	P186L	186	Missense	distal	-3	no	13.186	12.802	EPSD;PhosphoSitePlus	COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q15366	PCBP2	P28482	MAPK1	S208	S215T	215	Missense	distal	7	no	9.677	9.830	EPSD	COSMIC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q15366	PCBP2	P28482	MAPK1	S208	P210S	210	Missense	proximal	2	no	9.677	9.650	EPSD	COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q15366	PCBP2	P28482	MAPK1	S208	G203V	203	Missense	distal	-5	no	9.677	9.706	EPSD	COSMIC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q15366	PCBP2	P28482	MAPK1	T213	P214S	214	Missense	proximal	1	no	12.889	3.494	EPSD;PhosphoSitePlus	COSMIC	8.102	Loss
CMGC_MAPK_ERK1_MAPK1_ST	Q15366	PCBP2	P28482	MAPK1	T213	S215T	215	Missense	proximal	2	no	12.889	12.867	EPSD;PhosphoSitePlus	COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q15366	PCBP2	P28482	MAPK1	T213	P210S	210	Missense	distal	-3	no	12.889	12.713	EPSD;PhosphoSitePlus	COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q15366	PCBP2	P28482	MAPK1	S272	S271R	271	Missense	proximal	-1	no	14.683	14.707	PhosphoSitePlus;EPSD	COSMIC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q15366	PCBP2	P28482	MAPK1	S272	S270T	270	Missense	proximal	-2	no	14.683	14.818	PhosphoSitePlus;EPSD	COSMIC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q15366	PCBP2	P28482	MAPK1	S272	S266T	266	Missense	distal	-6	no	14.683	14.660	PhosphoSitePlus;EPSD	COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q8N9N5	BANP	P28482	MAPK1	S90	S90N	90	Missense	central	0	yes	12.929	0.000	EPSD	COSMIC	8.102	Loss
CMGC_MAPK_ERK1_MAPK1_ST	Q8N9N5	BANP	P28482	MAPK1	S100	S100F	100	Missense	central	0	yes	14.601	0.000	EPSD	COSMIC	8.102	Loss
CMGC_MAPK_ERK1_MAPK1_ST	Q8N9N5	BANP	P28482	MAPK1	T337	R335Q	335	Missense	proximal	-2	no	15.315	14.139	PhosphoSitePlus;EPSD	COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q8N9N5	BANP	P28482	MAPK1	T337	S341P	341	Missense	distal	4	no	15.315	15.325	PhosphoSitePlus;EPSD	COSMIC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q8N9N5	BANP	P28482	MAPK1	T337	S332R	332	Missense	distal	-5	no	15.315	15.288	PhosphoSitePlus;EPSD	COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q8N9N5	BANP	P28482	MAPK1	T352	P348S	348	Missense	distal	-4	no	12.550	12.466	EPSD;PhosphoSitePlus	COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q8N9N5	BANP	P28482	MAPK1	T352	S357R	357	Missense	distal	5	no	12.550	12.582	EPSD;PhosphoSitePlus	COSMIC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	O00429	DNM1L	P28482	MAPK1	S126	S119L	119	Missense	distal	-7	no	15.951	15.943	EPSD	COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	O00429	DNM1L	P28482	MAPK1	S126	K133N	133	Missense	distal	7	no	15.951	15.985	EPSD	COSMIC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	O00429	DNM1L	P28482	MAPK1	S126	G124E	124	Missense	proximal	-2	no	15.951	16.765	EPSD	COSMIC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	O00429	DNM1L	P28482	MAPK1	S126	G124R	124	Missense	proximal	-2	no	15.951	17.326	EPSD	COSMIC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	O00429	DNM1L	P28482	MAPK1	S126	G120C	120	Missense	distal	-6	no	15.951	15.827	EPSD	COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	O00429	DNM1L	P28482	MAPK1	S136	K133N	133	Missense	distal	-3	no	15.773	15.870	EPSD	COSMIC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	O00429	DNM1L	P28482	MAPK1	S330	G323C	323	Missense	distal	-7	no	8.269	8.251	EPSD	COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	O00429	DNM1L	P28482	MAPK1	S330	L333S	333	Missense	distal	3	no	8.269	8.249	EPSD	COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	O00429	DNM1L	P28482	MAPK1	S330	S330F	330	Missense	central	0	yes	8.269	0.000	EPSD	COSMIC	8.102	Loss
CMGC_MAPK_ERK1_MAPK1_ST	O00429	DNM1L	P28482	MAPK1	S330	D328H	328	Missense	proximal	-2	no	8.269	8.816	EPSD	COSMIC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	O00429	DNM1L	P28482	MAPK1	S412	V417A	417	Missense	distal	5	no	10.268	10.251	EPSD	COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	O00429	DNM1L	P28482	MAPK1	S412	R419W	419	Missense	distal	7	no	10.268	11.239	EPSD	COSMIC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	O00429	DNM1L	P28482	MAPK1	S412	P409S	409	Missense	distal	-3	no	10.268	10.091	EPSD	COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	O00429	DNM1L	P28482	MAPK1	S526	D531H	531	Missense	distal	5	no	8.336	8.165	EPSD	COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	O00429	DNM1L	P28482	MAPK1	S526	E523D	523	Missense	distal	-3	no	8.336	8.387	EPSD	COSMIC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	O00429	DNM1L	P28482	MAPK1	S526	S529L	529	Missense	distal	3	no	8.336	8.356	EPSD	COSMIC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	O00429	DNM1L	P28482	MAPK1	S526	S526L	526	Missense	central	0	yes	8.336	0.000	EPSD	COSMIC	8.102	Loss
CMGC_MAPK_ERK1_MAPK1_ST	O00429	DNM1L	P28482	MAPK1	S548	A543S	543	Missense	distal	-5	no	14.142	14.092	EPSD	COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	O00429	DNM1L	P28482	MAPK1	S548	Q545K	545	Missense	distal	-3	no	14.142	14.181	EPSD	COSMIC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	O00429	DNM1L	P28482	MAPK1	S616	P611L	611	Missense	distal	-5	no	14.544	14.693	PhosphoSitePlus	COSMIC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	O00429	DNM1L	P28482	MAPK1	S616	A622D	622	Missense	distal	6	no	14.544	14.795	PhosphoSitePlus	COSMIC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q5T447	HECTD3	P28482	MAPK1	S389	R395H	395	Missense	distal	6	no	8.200	8.001	EPSD	COSMIC;GDSC;CCLE	8.102	Loss
CMGC_MAPK_ERK1_MAPK1_ST	Q5T447	HECTD3	P28482	MAPK1	S389	S389N	389	Missense	central	0	yes	8.200	0.000	EPSD	COSMIC	8.102	Loss
CMGC_MAPK_ERK1_MAPK1_ST	Q5T447	HECTD3	P28482	MAPK1	S389	R395Q	395	Missense	distal	6	no	8.200	8.019	EPSD	COSMIC	8.102	Loss
CMGC_MAPK_ERK1_MAPK1_ST	Q5T447	HECTD3	P28482	MAPK1	S389	R395W	395	Missense	distal	6	no	8.200	7.277	EPSD	COSMIC	8.102	Loss
CMGC_MAPK_ERK1_MAPK1_ST	Q5T447	HECTD3	P28482	MAPK1	S857	W859L	859	Missense	proximal	2	no	17.229	17.337	EPSD	COSMIC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q5T447	HECTD3	P28482	MAPK1	S857	A851V	851	Missense	distal	-6	no	17.229	17.182	EPSD	COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P00533	EGFR	P28482	MAPK1	S227	G221V	221	Missense	distal	-6	no	13.009	12.966	EPSD	COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P00533	EGFR	P28482	MAPK1	S227	R222H	222	Missense	distal	-5	no	13.009	13.086	EPSD	COSMIC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P00533	EGFR	P28482	MAPK1	S227	G221W	221	Missense	distal	-6	no	13.009	12.840	EPSD	COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P00533	EGFR	P28482	MAPK1	S227	S227Y	227	Missense	central	0	yes	13.009	0.000	EPSD	COSMIC	8.102	Loss
CMGC_MAPK_ERK1_MAPK1_ST	P00533	EGFR	P28482	MAPK1	S227	G225C	225	Missense	proximal	-2	no	13.009	12.437	EPSD	COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P00533	EGFR	P28482	MAPK1	S227	S220F	220	Missense	distal	-7	no	13.009	12.989	EPSD	COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P00533	EGFR	P28482	MAPK1	S227	C231S	231	Missense	distal	4	no	13.009	13.291	EPSD	COSMIC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P00533	EGFR	P28482	MAPK1	S229	S227Y	227	Missense	proximal	-2	no	7.688	8.405	EPSD	COSMIC	8.102	Gain
CMGC_MAPK_ERK1_MAPK1_ST	P00533	EGFR	P28482	MAPK1	S511	A508V	508	Missense	distal	-3	no	13.698	13.757	EPSD	COSMIC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P00533	EGFR	P28482	MAPK1	S511	L509F	509	Missense	proximal	-2	no	13.698	12.974	EPSD	COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P00533	EGFR	P28482	MAPK1	S511	S511Y	511	Missense	central	0	yes	13.698	0.000	EPSD	COSMIC	8.102	Loss
CMGC_MAPK_ERK1_MAPK1_ST	P00533	EGFR	P28482	MAPK1	T693	A698V	698	Missense	distal	5	no	16.959	16.976	PhosphoSitePlus	COSMIC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P00533	EGFR	P28482	MAPK1	T693	P691T	691	Missense	proximal	-2	no	16.959	14.260	PhosphoSitePlus	COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P00533	EGFR	P28482	MAPK1	T693	L688P	688	Missense	distal	-5	no	16.959	16.810	PhosphoSitePlus	COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P00533	EGFR	P28482	MAPK1	T693	V689M	689	Missense	distal	-4	no	16.959	16.848	PhosphoSitePlus	COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P00533	EGFR	P28482	MAPK1	T693	N700Y	700	Missense	distal	7	no	16.959	17.494	PhosphoSitePlus	COSMIC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P00533	EGFR	P28482	MAPK1	T693	L692P	692	Missense	proximal	-1	no	16.959	17.019	PhosphoSitePlus	COSMIC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P00533	EGFR	P28482	MAPK1	T693	P694S	694	Missense	proximal	1	no	16.959	7.564	PhosphoSitePlus	COSMIC	8.102	Loss
CMGC_MAPK_ERK1_MAPK1_ST	P00533	EGFR	P28482	MAPK1	T693	N700S	700	Missense	distal	7	no	16.959	16.977	PhosphoSitePlus	COSMIC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P00533	EGFR	P28482	MAPK1	T693	E690K	690	Missense	distal	-3	no	16.959	16.881	PhosphoSitePlus	COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P00533	EGFR	P28482	MAPK1	T693	P691S	691	Missense	proximal	-2	no	16.959	14.125	PhosphoSitePlus	COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P00533	EGFR	P28482	MAPK1	T693	V689L	689	Missense	distal	-4	no	16.959	17.009	PhosphoSitePlus	COSMIC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P00533	EGFR	P28482	MAPK1	T693	E697D	697	Missense	distal	4	no	16.959	16.889	PhosphoSitePlus	COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P00533	EGFR	P28482	MAPK1	T693	P694L	694	Missense	proximal	1	no	16.959	8.150	PhosphoSitePlus	COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P00533	EGFR	P28482	MAPK1	T693	L688F	688	Missense	distal	-5	no	16.959	16.973	PhosphoSitePlus	COSMIC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P00533	EGFR	P28482	MAPK1	T693	N700D	700	Missense	distal	7	no	16.959	16.973	PhosphoSitePlus	COSMIC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P00533	EGFR	P28482	MAPK1	T693	S695G	695	Missense	proximal	2	no	16.959	17.006	PhosphoSitePlus	COSMIC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P00533	EGFR	P28482	MAPK1	T693	R686S	686	Missense	distal	-7	no	16.959	16.960	PhosphoSitePlus	COSMIC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P00533	EGFR	P28482	MAPK1	T693	T693A	693	Missense	central	0	yes	16.959	0.000	PhosphoSitePlus	COSMIC	8.102	Loss
CMGC_MAPK_ERK1_MAPK1_ST	P00533	EGFR	P28482	MAPK1	T693	E690V	690	Missense	distal	-3	no	16.959	16.832	PhosphoSitePlus	COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P00533	EGFR	P28482	MAPK1	T693	L692F	692	Missense	proximal	-1	no	16.959	16.930	PhosphoSitePlus	COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P00533	EGFR	P28482	MAPK1	T693	G696R	696	Missense	distal	3	no	16.959	16.922	PhosphoSitePlus	COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P00533	EGFR	P28482	MAPK1	T693	G696E	696	Missense	distal	3	no	16.959	16.866	PhosphoSitePlus	COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P00533	EGFR	P28482	MAPK1	S720	G721W	721	Missense	proximal	1	no	5.532	8.222	EPSD	COSMIC	8.102	Gain
CMGC_MAPK_ERK1_MAPK1_ST	P00533	EGFR	P28482	MAPK1	S752	L747P	747	Missense	distal	-5	no	15.051	14.902	EPSD	COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P00533	EGFR	P28482	MAPK1	S752	L747F	747	Missense	distal	-5	no	15.051	15.065	EPSD	COSMIC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P00533	EGFR	P28482	MAPK1	S752	L747H	747	Missense	distal	-5	no	15.051	15.027	EPSD	COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P00533	EGFR	P28482	MAPK1	S752	L747S	747	Missense	distal	-5	no	15.051	14.976	EPSD	COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P00533	EGFR	P28482	MAPK1	S752	A750P	750	Missense	proximal	-2	no	15.051	18.198	EPSD	COSMIC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P00533	EGFR	P28482	MAPK1	S752	R748K	748	Missense	distal	-4	no	15.051	15.130	EPSD	COSMIC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P00533	EGFR	P28482	MAPK1	S752	I759V	759	Missense	distal	7	no	15.051	14.786	EPSD	COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P00533	EGFR	P28482	MAPK1	S752	K754Q	754	Missense	proximal	2	no	15.051	14.941	EPSD	COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P00533	EGFR	P28482	MAPK1	S752	T751A	751	Missense	proximal	-1	no	15.051	15.056	EPSD	COSMIC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P00533	EGFR	P28482	MAPK1	S752	E758G	758	Missense	distal	6	no	15.051	14.940	EPSD	COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P00533	EGFR	P28482	MAPK1	S752	K757N	757	Missense	distal	5	no	15.051	15.082	EPSD	COSMIC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P00533	EGFR	P28482	MAPK1	S752	S752Y	752	Missense	central	0	yes	15.051	0.000	EPSD	COSMIC	8.102	Loss
CMGC_MAPK_ERK1_MAPK1_ST	P00533	EGFR	P28482	MAPK1	S752	T751I	751	Missense	proximal	-1	no	15.051	15.027	EPSD	COSMIC;GDSC;CCLE	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P00533	EGFR	P28482	MAPK1	S752	E746V	746	Missense	distal	-6	no	15.051	14.954	EPSD	COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P00533	EGFR	P28482	MAPK1	S752	A750T	750	Missense	proximal	-2	no	15.051	15.499	EPSD	COSMIC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P00533	EGFR	P28482	MAPK1	S752	S752F	752	Missense	central	0	yes	15.051	0.000	EPSD	COSMIC	8.102	Loss
CMGC_MAPK_ERK1_MAPK1_ST	P00533	EGFR	P28482	MAPK1	S752	E746A	746	Missense	distal	-6	no	15.051	15.001	EPSD	COSMIC;GDSC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P00533	EGFR	P28482	MAPK1	S752	A755D	755	Missense	distal	3	no	15.051	15.060	EPSD	COSMIC;CCLE	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P00533	EGFR	P28482	MAPK1	S752	K754R	754	Missense	proximal	2	no	15.051	15.232	EPSD	COSMIC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P00533	EGFR	P28482	MAPK1	S752	E749K	749	Missense	distal	-3	no	15.051	14.973	EPSD	COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P00533	EGFR	P28482	MAPK1	S752	T751L	751	Missense	proximal	-1	no	15.051	15.033	EPSD	COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P00533	EGFR	P28482	MAPK1	S752	E758K	758	Missense	distal	6	no	15.051	15.075	EPSD	COSMIC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P00533	EGFR	P28482	MAPK1	S752	K745R	745	Missense	distal	-7	no	15.051	15.048	EPSD	COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P00533	EGFR	P28482	MAPK1	S752	E746I	746	Missense	distal	-6	no	15.051	14.913	EPSD	COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P00533	EGFR	P28482	MAPK1	S752	A755T	755	Missense	distal	3	no	15.051	15.035	EPSD	COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P00533	EGFR	P28482	MAPK1	S752	K754A	754	Missense	proximal	2	no	15.051	14.989	EPSD	COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P00533	EGFR	P28482	MAPK1	S752	N756S	756	Missense	distal	4	no	15.051	15.089	EPSD	COSMIC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P00533	EGFR	P28482	MAPK1	S752	N756Y	756	Missense	distal	4	no	15.051	14.894	EPSD	COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P00533	EGFR	P28482	MAPK1	S752	K757R	757	Missense	distal	5	no	15.051	15.186	EPSD	COSMIC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P00533	EGFR	P28482	MAPK1	S752	A755G	755	Missense	distal	3	no	15.051	15.057	EPSD	COSMIC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P00533	EGFR	P28482	MAPK1	S752	E746G	746	Missense	distal	-6	no	15.051	14.997	EPSD	COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P00533	EGFR	P28482	MAPK1	S752	E749V	749	Missense	distal	-3	no	15.051	14.924	EPSD	COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P00533	EGFR	P28482	MAPK1	S752	E749G	749	Missense	distal	-3	no	15.051	15.042	EPSD	COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P00533	EGFR	P28482	MAPK1	S752	S752P	752	Missense	central	0	yes	15.051	0.000	EPSD	COSMIC	8.102	Loss
CMGC_MAPK_ERK1_MAPK1_ST	P00533	EGFR	P28482	MAPK1	S752	E758D	758	Missense	distal	6	no	15.051	14.972	EPSD	COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P00533	EGFR	P28482	MAPK1	S752	K745T	745	Missense	distal	-7	no	15.051	15.036	EPSD	COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P00533	EGFR	P28482	MAPK1	S752	E746K	746	Missense	distal	-6	no	15.051	15.025	EPSD	COSMIC;GDSC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P00533	EGFR	P28482	MAPK1	S752	A755V	755	Missense	distal	3	no	15.051	15.030	EPSD	COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P00533	EGFR	P28482	MAPK1	S752	L747V	747	Missense	distal	-5	no	15.051	14.998	EPSD	COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P00533	EGFR	P28482	MAPK1	S752	T751P	751	Missense	proximal	-1	no	15.051	15.093	EPSD	COSMIC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P00533	EGFR	P28482	MAPK1	S752	R748I	748	Missense	distal	-4	no	15.051	14.470	EPSD	COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P00533	EGFR	P28482	MAPK1	S752	K757M	757	Missense	distal	5	no	15.051	14.950	EPSD	COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P00533	EGFR	P28482	MAPK1	S752	P753F	753	Missense	proximal	1	no	15.051	8.482	EPSD	COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P00533	EGFR	P28482	MAPK1	S991	F997L	997	Missense	distal	6	no	14.909	14.943	EPSD	COSMIC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P00533	EGFR	P28482	MAPK1	S991	D984N	984	Missense	distal	-7	no	14.909	14.910	EPSD	COSMIC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P00533	EGFR	P28482	MAPK1	S991	M987R	987	Missense	distal	-4	no	14.909	15.285	EPSD	COSMIC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P00533	EGFR	P28482	MAPK1	S1026	S1025T	1025	Missense	proximal	-1	no	13.873	13.874	EPSD	COSMIC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P00533	EGFR	P28482	MAPK1	S1026	P1027S	1027	Missense	proximal	1	no	13.873	4.478	EPSD	COSMIC	8.102	Loss
CMGC_MAPK_ERK1_MAPK1_ST	P00533	EGFR	P28482	MAPK1	S1026	P1019S	1019	Missense	distal	-7	no	13.873	13.869	EPSD	COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P00533	EGFR	P28482	MAPK1	S1026	G1022S	1022	Missense	distal	-4	no	13.873	14.139	EPSD	COSMIC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P00533	EGFR	P28482	MAPK1	S1026	S1028L	1028	Missense	proximal	2	no	13.873	13.754	EPSD	COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P00533	EGFR	P28482	MAPK1	S1026	Q1020H	1020	Missense	distal	-6	no	13.873	13.814	EPSD	COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P00533	EGFR	P28482	MAPK1	T1032	S1025T	1025	Missense	distal	-7	no	12.261	12.249	EPSD	COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P00533	EGFR	P28482	MAPK1	T1032	P1027S	1027	Missense	distal	-5	no	12.261	12.335	EPSD	COSMIC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P00533	EGFR	P28482	MAPK1	T1032	S1036R	1036	Missense	distal	4	no	12.261	12.239	EPSD	COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P00533	EGFR	P28482	MAPK1	T1032	S1028L	1028	Missense	distal	-4	no	12.261	12.041	EPSD	COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P00533	EGFR	P28482	MAPK1	T1032	L1034I	1034	Missense	proximal	2	no	12.261	12.238	EPSD	COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P00533	EGFR	P28482	MAPK1	S1039	T1041A	1041	Missense	proximal	2	no	8.103	8.024	EPSD	COSMIC	8.102	Loss
CMGC_MAPK_ERK1_MAPK1_ST	P00533	EGFR	P28482	MAPK1	S1039	S1036R	1036	Missense	distal	-3	no	8.103	8.260	EPSD	COSMIC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P00533	EGFR	P28482	MAPK1	S1039	L1034I	1034	Missense	distal	-5	no	8.103	8.164	EPSD	COSMIC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P00533	EGFR	P28482	MAPK1	S1039	S1045F	1045	Missense	distal	6	no	8.103	7.663	EPSD	COSMIC	8.102	Loss
CMGC_MAPK_ERK1_MAPK1_ST	P00533	EGFR	P28482	MAPK1	S1039	T1046I	1046	Missense	distal	7	no	8.103	8.499	EPSD	COSMIC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P00533	EGFR	P28482	MAPK1	S1057	C1058Y	1058	Missense	proximal	1	no	2.496	8.935	EPSD	COSMIC	8.102	Gain
CMGC_MAPK_ERK1_MAPK1_ST	P00533	EGFR	P28482	MAPK1	T1085	D1084G	1084	Missense	proximal	-1	no	8.248	8.249	EPSD	COSMIC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P00533	EGFR	P28482	MAPK1	T1085	D1083G	1083	Missense	proximal	-2	no	8.248	8.355	EPSD	COSMIC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P00533	EGFR	P28482	MAPK1	T1085	P1088S	1088	Missense	distal	3	no	8.248	8.317	EPSD	COSMIC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P00533	EGFR	P28482	MAPK1	S1130	H1124Q	1124	Missense	distal	-6	no	8.862	8.922	EPSD	COSMIC;CCLE	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P00533	EGFR	P28482	MAPK1	S1130	E1137K	1137	Missense	distal	7	no	8.862	8.870	EPSD	COSMIC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P00533	EGFR	P28482	MAPK1	S1130	S1130G	1130	Missense	central	0	yes	8.862	0.000	EPSD	COSMIC;GDSC;CCLE	8.102	Loss
CMGC_MAPK_ERK1_MAPK1_ST	P00533	EGFR	P28482	MAPK1	S1130	H1129Y	1129	Missense	proximal	-1	no	8.862	8.830	EPSD	COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P00533	EGFR	P28482	MAPK1	S1130	P1136L	1136	Missense	distal	6	no	8.862	8.456	EPSD	COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P00533	EGFR	P28482	MAPK1	S1130	S1130R	1130	Missense	central	0	yes	8.862	0.000	EPSD	COSMIC	8.102	Loss
CMGC_MAPK_ERK1_MAPK1_ST	P00533	EGFR	P28482	MAPK1	S1130	P1136A	1136	Missense	distal	6	no	8.862	8.566	EPSD	COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P00533	EGFR	P28482	MAPK1	S1130	D1127N	1127	Missense	distal	-3	no	8.862	8.830	EPSD	COSMIC;GDSC;CCLE	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P00533	EGFR	P28482	MAPK1	T1150	A1155D	1155	Missense	distal	5	no	7.986	8.171	EPSD	COSMIC	8.102	Gain
CMGC_MAPK_ERK1_MAPK1_ST	P00533	EGFR	P28482	MAPK1	S1153	A1155D	1155	Missense	proximal	2	no	14.713	14.827	EPSD	COSMIC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P00533	EGFR	P28482	MAPK1	S1153	V1147I	1147	Missense	distal	-6	no	14.713	14.672	EPSD	COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P00533	EGFR	P28482	MAPK1	S1153	Q1159H	1159	Missense	distal	6	no	14.713	14.695	EPSD	COSMIC;GDSC;CCLE	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P00533	EGFR	P28482	MAPK1	S1153	A1158P	1158	Missense	distal	5	no	14.713	14.855	EPSD	COSMIC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P00533	EGFR	P28482	MAPK1	S1153	D1152H	1152	Missense	proximal	-1	no	14.713	14.726	EPSD	COSMIC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P00533	EGFR	P28482	MAPK1	S1204	R1199M	1199	Missense	distal	-5	no	9.983	10.088	EPSD	COSMIC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P00533	EGFR	P28482	MAPK1	S1204	S1204R	1204	Missense	central	0	yes	9.983	0.000	EPSD	COSMIC	8.102	Loss
CMGC_MAPK_ERK1_MAPK1_ST	P00533	EGFR	P28482	MAPK1	S1204	A1201T	1201	Missense	distal	-3	no	9.983	10.140	EPSD	COSMIC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P00533	EGFR	P28482	MAPK1	S1204	F1207C	1207	Missense	distal	3	no	9.983	10.024	EPSD	COSMIC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P00533	EGFR	P28482	MAPK1	S1204	R1199T	1199	Missense	distal	-5	no	9.983	10.038	EPSD	COSMIC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P00533	EGFR	P28482	MAPK1	S1204	V1200I	1200	Missense	distal	-4	no	9.983	9.666	EPSD	COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P00533	EGFR	P28482	MAPK1	S1205	R1199M	1199	Missense	distal	-6	no	8.412	8.320	EPSD	COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P00533	EGFR	P28482	MAPK1	S1205	S1204R	1204	Missense	proximal	-1	no	8.412	8.436	EPSD	COSMIC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P00533	EGFR	P28482	MAPK1	S1205	A1201T	1201	Missense	distal	-4	no	8.412	8.392	EPSD	COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P00533	EGFR	P28482	MAPK1	S1205	F1207C	1207	Missense	proximal	2	no	8.412	8.312	EPSD	COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P00533	EGFR	P28482	MAPK1	S1205	R1199T	1199	Missense	distal	-6	no	8.412	8.354	EPSD	COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P00533	EGFR	P28482	MAPK1	S1205	V1200I	1200	Missense	distal	-5	no	8.412	8.525	EPSD	COSMIC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P14635	CCNB1	P28482	MAPK1	T29	T34I	34	Missense	distal	5	no	8.260	8.016	EPSD	COSMIC	8.102	Loss
CMGC_MAPK_ERK1_MAPK1_ST	P14635	CCNB1	P28482	MAPK1	S116	E113D	113	Missense	distal	-3	no	15.847	15.898	EPSD	COSMIC;GDSC;CCLE	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q9H9S0	NANOG	P28482	MAPK1	S52	V51F	51	Missense	proximal	-1	no	10.829	10.765	PhosphoSitePlus;EPSD	COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q9H9S0	NANOG	P28482	MAPK1	S52	L54V	54	Missense	proximal	2	no	10.829	10.923	PhosphoSitePlus;EPSD	COSMIC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q9H9S0	NANOG	P28482	MAPK1	S65	S69P	69	Missense	distal	4	no	15.041	15.052	EPSD;PhosphoSitePlus	COSMIC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q9H9S0	NANOG	P28482	MAPK1	S65	S65N	65	Missense	central	0	yes	15.041	0.000	EPSD;PhosphoSitePlus	COSMIC	8.102	Loss
CMGC_MAPK_ERK1_MAPK1_ST	Q9H9S0	NANOG	P28482	MAPK1	S71	S69P	69	Missense	proximal	-2	no	11.627	14.461	EPSD	COSMIC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q9H9S0	NANOG	P28482	MAPK1	S71	S65N	65	Missense	distal	-6	no	11.627	11.630	EPSD	COSMIC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q9H9S0	NANOG	P28482	MAPK1	S258	P259S	259	Missense	proximal	1	no	17.279	7.884	EPSD	COSMIC	8.102	Loss
CMGC_MAPK_ERK1_MAPK1_ST	Q8IW41	MAPKAPK5	P28482	MAPK1	T182	Q184E	184	Missense	proximal	2	no	12.230	12.340	PhosphoSitePlus	COSMIC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q8IW41	MAPKAPK5	P28482	MAPK1	T182	T186I	186	Missense	distal	4	no	12.230	12.177	PhosphoSitePlus	COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q8IW41	MAPKAPK5	P28482	MAPK1	T186	Q184E	184	Missense	proximal	-2	no	15.853	16.467	EPSD	COSMIC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q8IW41	MAPKAPK5	P28482	MAPK1	T186	T186I	186	Missense	central	0	yes	15.853	0.000	EPSD	COSMIC	8.102	Loss
CMGC_MAPK_ERK1_MAPK1_ST	Q8IW41	MAPKAPK5	P28482	MAPK1	T217	D223N	223	Missense	distal	6	no	11.667	11.616	EPSD	COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q8IW41	MAPKAPK5	P28482	MAPK1	S469	E465V	465	Missense	distal	-4	no	8.799	8.474	EPSD	COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q8IW41	MAPKAPK5	P28482	MAPK1	S469	S472Y	472	Missense	distal	3	no	8.799	8.858	EPSD	COSMIC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P61978	HNRNPK	P28482	MAPK1	S116	L123P	123	Missense	distal	7	no	16.136	15.836	EPSD	COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P61978	HNRNPK	P28482	MAPK1	S116	T118A	118	Missense	proximal	2	no	16.136	16.057	EPSD	COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P61978	HNRNPK	P28482	MAPK1	S284	M283T	283	Missense	proximal	-1	no	14.740	14.747	PhosphoSitePlus	COSMIC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P61978	HNRNPK	P28482	MAPK1	S379	G376D	376	Missense	distal	-3	no	10.565	10.625	EPSD	COSMIC;CCLE	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P61978	HNRNPK	P28482	MAPK1	S379	S372A	372	Missense	distal	-7	no	10.565	10.567	EPSD	COSMIC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P07196	NEFL	P28482	MAPK1	S11	R16W	16	Missense	distal	5	no	8.388	7.859	EPSD	COSMIC	8.102	Loss
CMGC_MAPK_ERK1_MAPK1_ST	P07196	NEFL	P28482	MAPK1	S11	P8R	8	Missense	distal	-3	no	8.388	8.368	EPSD	COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P07196	NEFL	P28482	MAPK1	S11	T12S	12	Missense	proximal	1	no	8.388	7.491	EPSD	COSMIC	8.102	Loss
CMGC_MAPK_ERK1_MAPK1_ST	P07196	NEFL	P28482	MAPK1	S11	Y9N	9	Missense	proximal	-2	no	8.388	7.685	EPSD	COSMIC	8.102	Loss
CMGC_MAPK_ERK1_MAPK1_ST	P07196	NEFL	P28482	MAPK1	S11	R16Q	16	Missense	distal	5	no	8.388	8.218	EPSD	COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P07196	NEFL	P28482	MAPK1	T21	R16W	16	Missense	distal	-5	no	15.702	15.978	PhosphoSitePlus	COSMIC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P07196	NEFL	P28482	MAPK1	T21	H25N	25	Missense	distal	4	no	15.702	15.829	PhosphoSitePlus	COSMIC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P07196	NEFL	P28482	MAPK1	T21	S28N	28	Missense	distal	7	no	15.702	15.685	PhosphoSitePlus	COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P07196	NEFL	P28482	MAPK1	T21	R16Q	16	Missense	distal	-5	no	15.702	15.780	PhosphoSitePlus	COSMIC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P07196	NEFL	P28482	MAPK1	S48	P46Q	46	Missense	proximal	-2	no	8.626	5.633	EPSD	COSMIC	8.102	Loss
CMGC_MAPK_ERK1_MAPK1_ST	P07196	NEFL	P28482	MAPK1	S48	R55G	55	Missense	distal	7	no	8.626	8.692	EPSD	COSMIC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P07196	NEFL	P28482	MAPK1	S48	A45V	45	Missense	distal	-3	no	8.626	8.686	EPSD	COSMIC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P07196	NEFL	P28482	MAPK1	S48	S50L	50	Missense	proximal	2	no	8.626	8.507	EPSD	COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P07196	NEFL	P28482	MAPK1	S48	Y43C	43	Missense	distal	-5	no	8.626	8.699	EPSD	COSMIC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P07196	NEFL	P28482	MAPK1	S48	R54H	54	Missense	distal	6	no	8.626	8.428	EPSD	COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P07196	NEFL	P28482	MAPK1	S48	R55H	55	Missense	distal	7	no	8.626	8.846	EPSD	COSMIC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P29966	MARCKS	P28482	MAPK1	S118	A122T	122	Missense	distal	4	no	16.251	16.232	EPSD	COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P29966	MARCKS	P28482	MAPK1	S118	T120M	120	Missense	proximal	2	no	16.251	16.111	EPSD	COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P29966	MARCKS	P28482	MAPK1	S135	S131A	131	Missense	distal	-4	no	13.528	13.319	EPSD	COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P29966	MARCKS	P28482	MAPK1	S135	A142P	142	Missense	distal	7	no	13.528	13.336	EPSD	COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P29966	MARCKS	P28482	MAPK1	T143	A142P	142	Missense	proximal	-1	no	11.782	11.819	EPSD	COSMIC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P29966	MARCKS	P28482	MAPK1	S145	A142P	142	Missense	distal	-3	no	13.205	13.572	EPSD	COSMIC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	O43524	FOXO3	P28482	MAPK1	S7	A2V	2	Missense	distal	-5	no	17.200	17.172	EPSD	COSMIC;CCLE	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	O43524	FOXO3	P28482	MAPK1	S7	A6S	6	Missense	proximal	-1	no	17.200	17.194	EPSD	COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	O43524	FOXO3	P28482	MAPK1	S12	A6S	6	Missense	distal	-6	no	18.335	18.348	EPSD;PhosphoSitePlus	COSMIC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	O43524	FOXO3	P28482	MAPK1	S26	R29L	29	Missense	distal	3	no	10.103	10.147	EPSD	COSMIC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	O43524	FOXO3	P28482	MAPK1	S43	E50D	50	Missense	distal	7	no	12.087	12.142	EPSD	COSMIC;CCLE	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	O43524	FOXO3	P28482	MAPK1	S280	Q275R	275	Missense	distal	-5	no	9.635	9.558	EPSD	COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	O43524	FOXO3	P28482	MAPK1	S294	P295L	295	Missense	proximal	1	no	15.577	6.767	PhosphoSitePlus;EPSD	COSMIC	8.102	Loss
CMGC_MAPK_ERK1_MAPK1_ST	O43524	FOXO3	P28482	MAPK1	S325	S318C	318	Missense	distal	-7	no	14.621	14.589	EPSD	COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	O43524	FOXO3	P28482	MAPK1	S325	R323C	323	Missense	proximal	-2	no	14.621	12.673	EPSD	COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	O43524	FOXO3	P28482	MAPK1	S325	E332Q	332	Missense	distal	7	no	14.621	14.799	EPSD	COSMIC;CCLE	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	O43524	FOXO3	P28482	MAPK1	S325	R323H	323	Missense	proximal	-2	no	14.621	13.685	EPSD	COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	O43524	FOXO3	P28482	MAPK1	S344	A341T	341	Missense	distal	-3	no	18.067	18.225	EPSD;PhosphoSitePlus	COSMIC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	O43524	FOXO3	P28482	MAPK1	S355	P361L	361	Missense	distal	6	no	14.583	14.176	EPSD	COSMIC;GDSC;CCLE	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	O43524	FOXO3	P28482	MAPK1	S402	P397R	397	Missense	distal	-5	no	13.773	13.821	EPSD	COSMIC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	O43524	FOXO3	P28482	MAPK1	S425	G424V	424	Missense	proximal	-1	no	14.483	14.511	EPSD;PhosphoSitePlus	COSMIC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P24941	CDK2	P28482	MAPK1	T14	G13C	13	Missense	proximal	-1	no	8.636	8.568	EPSD	COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P24941	CDK2	P28482	MAPK1	T14	E12A	12	Missense	proximal	-2	no	8.636	7.869	EPSD	COSMIC	8.102	Loss
CMGC_MAPK_ERK1_MAPK1_ST	P24941	CDK2	P28482	MAPK1	T14	G13S	13	Missense	proximal	-1	no	8.636	8.647	EPSD	COSMIC;GDSC;CCLE	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P24941	CDK2	P28482	MAPK1	T47	P45L	45	Missense	proximal	-2	no	10.340	8.423	EPSD	COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P24941	CDK2	P28482	MAPK1	T47	E42K	42	Missense	distal	-5	no	10.340	10.317	EPSD	COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P24941	CDK2	P28482	MAPK1	T221	R217W	217	Missense	distal	-4	no	15.635	14.692	EPSD	COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P24941	CDK2	P28482	MAPK1	T221	R217L	217	Missense	distal	-4	no	15.635	15.420	EPSD	COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P24941	CDK2	P28482	MAPK1	T221	V226M	226	Missense	distal	5	no	15.635	15.573	EPSD	COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P24941	CDK2	P28482	MAPK1	T221	R214W	214	Missense	distal	-7	no	15.635	15.584	EPSD	COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q05209	PTPN12	P28482	MAPK1	S19	D26A	26	Missense	distal	7	no	15.780	15.965	EPSD	COSMIC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q05209	PTPN12	P28482	MAPK1	S39	M33I	33	Missense	distal	-6	no	9.162	9.119	EPSD	COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q05209	PTPN12	P28482	MAPK1	S186	R187P	187	Missense	proximal	1	no	4.097	13.752	EPSD	COSMIC	8.102	Gain
CMGC_MAPK_ERK1_MAPK1_ST	Q05209	PTPN12	P28482	MAPK1	S332	E326D	326	Missense	distal	-6	no	13.654	13.666	EPSD	COSMIC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q05209	PTPN12	P28482	MAPK1	S332	E326G	326	Missense	distal	-6	no	13.654	13.600	EPSD	COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q05209	PTPN12	P28482	MAPK1	S332	P335S	335	Missense	distal	3	no	13.654	13.723	EPSD	COSMIC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q05209	PTPN12	P28482	MAPK1	T340	R341H	341	Missense	proximal	1	no	8.833	10.664	EPSD	COSMIC;GDSC;CCLE	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q05209	PTPN12	P28482	MAPK1	T340	P335S	335	Missense	distal	-5	no	8.833	8.907	EPSD	COSMIC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q05209	PTPN12	P28482	MAPK1	T367	L366V	366	Missense	proximal	-1	no	13.750	13.783	EPSD	COSMIC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q05209	PTPN12	P28482	MAPK1	T367	P370S	370	Missense	distal	3	no	13.750	13.819	EPSD	COSMIC;GDSC;CCLE	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q05209	PTPN12	P28482	MAPK1	T367	P361L	361	Missense	distal	-6	no	13.750	13.658	EPSD	COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q05209	PTPN12	P28482	MAPK1	S369	L366V	366	Missense	distal	-3	no	12.491	12.567	EPSD	COSMIC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q05209	PTPN12	P28482	MAPK1	S369	P370S	370	Missense	proximal	1	no	12.491	3.096	EPSD	COSMIC;GDSC;CCLE	8.102	Loss
CMGC_MAPK_ERK1_MAPK1_ST	Q05209	PTPN12	P28482	MAPK1	S372	L366V	366	Missense	distal	-6	no	9.617	9.623	EPSD	COSMIC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q05209	PTPN12	P28482	MAPK1	S372	P370S	370	Missense	proximal	-2	no	9.617	6.783	EPSD	COSMIC;GDSC;CCLE	8.102	Loss
CMGC_MAPK_ERK1_MAPK1_ST	Q05209	PTPN12	P28482	MAPK1	S449	T454A	454	Missense	distal	5	no	8.326	8.240	EPSD	COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q05209	PTPN12	P28482	MAPK1	S449	T454I	454	Missense	distal	5	no	8.326	8.083	EPSD	COSMIC	8.102	Loss
CMGC_MAPK_ERK1_MAPK1_ST	Q05209	PTPN12	P28482	MAPK1	S449	D451N	451	Missense	proximal	2	no	8.326	8.266	EPSD	COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q05209	PTPN12	P28482	MAPK1	S449	E445G	445	Missense	distal	-4	no	8.326	8.005	EPSD	COSMIC	8.102	Loss
CMGC_MAPK_ERK1_MAPK1_ST	Q05209	PTPN12	P28482	MAPK1	S449	E445D	445	Missense	distal	-4	no	8.326	8.341	EPSD	COSMIC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q05209	PTPN12	P28482	MAPK1	S468	I462N	462	Missense	distal	-6	no	14.904	15.009	EPSD	COSMIC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q05209	PTPN12	P28482	MAPK1	S468	K463I	463	Missense	distal	-5	no	14.904	15.111	EPSD	COSMIC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q05209	PTPN12	P28482	MAPK1	S468	K474N	474	Missense	distal	6	no	14.904	14.751	EPSD	COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q05209	PTPN12	P28482	MAPK1	S468	I471V	471	Missense	distal	3	no	14.904	14.834	EPSD	COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q05209	PTPN12	P28482	MAPK1	T509	P511Q	511	Missense	proximal	2	no	12.461	12.283	EPSD	COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q05209	PTPN12	P28482	MAPK1	S517	P511Q	511	Missense	distal	-6	no	9.188	9.172	EPSD	COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q05209	PTPN12	P28482	MAPK1	T569	T574A	574	Missense	distal	5	no	11.581	11.495	EPSD	COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q05209	PTPN12	P28482	MAPK1	T569	T574I	574	Missense	distal	5	no	11.581	11.338	EPSD	COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q05209	PTPN12	P28482	MAPK1	T569	T574P	574	Missense	distal	5	no	11.581	11.637	EPSD	COSMIC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q05209	PTPN12	P28482	MAPK1	T569	T574S	574	Missense	distal	5	no	11.581	11.655	EPSD	COSMIC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q05209	PTPN12	P28482	MAPK1	T569	T573A	573	Missense	distal	4	no	11.581	11.601	EPSD	COSMIC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q05209	PTPN12	P28482	MAPK1	S571	T574A	574	Missense	distal	3	no	13.707	13.723	PhosphoSitePlus	COSMIC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q05209	PTPN12	P28482	MAPK1	S571	T574I	574	Missense	distal	3	no	13.707	13.772	PhosphoSitePlus	COSMIC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q05209	PTPN12	P28482	MAPK1	S571	T574P	574	Missense	distal	3	no	13.707	13.645	PhosphoSitePlus	COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q05209	PTPN12	P28482	MAPK1	S571	T574S	574	Missense	distal	3	no	13.707	13.714	PhosphoSitePlus	COSMIC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q05209	PTPN12	P28482	MAPK1	S571	T573A	573	Missense	proximal	2	no	13.707	13.628	PhosphoSitePlus	COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q05209	PTPN12	P28482	MAPK1	T573	T574P	574	Missense	proximal	1	no	5.459	13.958	EPSD	COSMIC	8.102	Gain
CMGC_MAPK_ERK1_MAPK1_ST	Q05209	PTPN12	P28482	MAPK1	T578	T574A	574	Missense	distal	-4	no	13.878	13.898	EPSD	COSMIC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q05209	PTPN12	P28482	MAPK1	T578	T574I	574	Missense	distal	-4	no	13.878	13.521	EPSD	COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q05209	PTPN12	P28482	MAPK1	T578	T574P	574	Missense	distal	-4	no	13.878	14.191	EPSD	COSMIC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q05209	PTPN12	P28482	MAPK1	T578	T574S	574	Missense	distal	-4	no	13.878	14.108	EPSD	COSMIC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q05209	PTPN12	P28482	MAPK1	T578	T573A	573	Missense	distal	-5	no	13.878	13.900	EPSD	COSMIC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q05209	PTPN12	P28482	MAPK1	T578	D585G	585	Missense	distal	7	no	13.878	13.951	EPSD	COSMIC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q05209	PTPN12	P28482	MAPK1	T578	L581I	581	Missense	distal	3	no	13.878	13.916	EPSD	COSMIC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q05209	PTPN12	P28482	MAPK1	S588	L590I	590	Missense	proximal	2	no	14.283	14.259	EPSD	COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q05209	PTPN12	P28482	MAPK1	S588	D585G	585	Missense	distal	-3	no	14.283	14.223	EPSD	COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q05209	PTPN12	P28482	MAPK1	S588	L581I	581	Missense	distal	-7	no	14.283	14.263	EPSD	COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q05209	PTPN12	P28482	MAPK1	T593	L590I	590	Missense	distal	-3	no	13.862	13.805	EPSD	COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q05209	PTPN12	P28482	MAPK1	S596	L590I	590	Missense	distal	-6	no	9.774	9.738	EPSD	COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q05209	PTPN12	P28482	MAPK1	S673	P676H	676	Missense	distal	3	no	11.964	12.053	EPSD	COSMIC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q05209	PTPN12	P28482	MAPK1	S673	R680K	680	Missense	distal	7	no	11.964	11.909	EPSD	COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q05209	PTPN12	P28482	MAPK1	S673	P678R	678	Missense	distal	5	no	11.964	12.014	EPSD	COSMIC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q05209	PTPN12	P28482	MAPK1	T681	P676H	676	Missense	distal	-5	no	12.353	12.478	EPSD	COSMIC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q05209	PTPN12	P28482	MAPK1	T681	R680K	680	Missense	proximal	-1	no	12.353	12.385	EPSD	COSMIC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q05209	PTPN12	P28482	MAPK1	T681	A688V	688	Missense	distal	7	no	12.353	12.455	EPSD	COSMIC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q05209	PTPN12	P28482	MAPK1	T681	P678R	678	Missense	distal	-3	no	12.353	12.333	EPSD	COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q05209	PTPN12	P28482	MAPK1	S684	R680K	680	Missense	distal	-4	no	10.959	11.038	EPSD	COSMIC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q05209	PTPN12	P28482	MAPK1	S684	A688V	688	Missense	distal	4	no	10.959	10.953	EPSD	COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q05209	PTPN12	P28482	MAPK1	S684	P678R	678	Missense	distal	-6	no	10.959	10.967	EPSD	COSMIC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q05209	PTPN12	P28482	MAPK1	T693	S697T	697	Missense	distal	4	no	12.171	12.059	EPSD	COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q05209	PTPN12	P28482	MAPK1	T693	E698Q	698	Missense	distal	5	no	12.171	12.077	EPSD	COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q05209	PTPN12	P28482	MAPK1	T693	W699L	699	Missense	distal	6	no	12.171	12.795	EPSD	COSMIC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q05209	PTPN12	P28482	MAPK1	T693	T693P	693	Missense	central	0	yes	12.171	0.000	EPSD	COSMIC	8.102	Loss
CMGC_MAPK_ERK1_MAPK1_ST	Q05209	PTPN12	P28482	MAPK1	T693	A688V	688	Missense	distal	-5	no	12.171	12.143	EPSD	COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q05209	PTPN12	P28482	MAPK1	T693	P694H	694	Missense	proximal	1	no	12.171	4.348	EPSD	COSMIC	8.102	Loss
CMGC_MAPK_ERK1_MAPK1_ST	Q05209	PTPN12	P28482	MAPK1	T693	T693A	693	Missense	central	0	yes	12.171	0.000	EPSD	COSMIC	8.102	Loss
CMGC_MAPK_ERK1_MAPK1_ST	Q05209	PTPN12	P28482	MAPK1	T693	T693I	693	Missense	central	0	yes	12.171	0.000	EPSD	COSMIC	8.102	Loss
CMGC_MAPK_ERK1_MAPK1_ST	Q05209	PTPN12	P28482	MAPK1	T693	N692K	692	Missense	proximal	-1	no	12.171	12.179	EPSD	COSMIC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q96Q27	ASB2	P28482	MAPK1	S28	P25S	25	Missense	distal	-3	no	9.722	9.545	EPSD	COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q96Q27	ASB2	P28482	MAPK1	S28	S29L	29	Missense	proximal	1	no	9.722	10.307	EPSD	COSMIC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q96Q27	ASB2	P28482	MAPK1	S28	R21S	21	Missense	distal	-7	no	9.722	9.723	EPSD	COSMIC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q96Q27	ASB2	P28482	MAPK1	S28	R32W	32	Missense	distal	4	no	9.722	9.438	EPSD	COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q96Q27	ASB2	P28482	MAPK1	S28	R32Q	32	Missense	distal	4	no	9.722	9.647	EPSD	COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q96Q27	ASB2	P28482	MAPK1	S28	M35I	35	Missense	distal	7	no	9.722	9.910	EPSD	COSMIC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q96Q27	ASB2	P28482	MAPK1	S28	E27Q	27	Missense	proximal	-1	no	9.722	9.696	EPSD	COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q96Q27	ASB2	P28482	MAPK1	S28	M35V	35	Missense	distal	7	no	9.722	9.645	EPSD	COSMIC;GDSC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q96Q27	ASB2	P28482	MAPK1	S29	P25S	25	Missense	distal	-4	no	14.784	14.700	EPSD	COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q96Q27	ASB2	P28482	MAPK1	S29	S29L	29	Missense	central	0	yes	14.784	0.000	EPSD	COSMIC	8.102	Loss
CMGC_MAPK_ERK1_MAPK1_ST	Q96Q27	ASB2	P28482	MAPK1	S29	R32W	32	Missense	distal	3	no	14.784	14.933	EPSD	COSMIC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q96Q27	ASB2	P28482	MAPK1	S29	R32Q	32	Missense	distal	3	no	14.784	14.806	EPSD	COSMIC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q96Q27	ASB2	P28482	MAPK1	S29	M35I	35	Missense	distal	6	no	14.784	14.550	EPSD	COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q96Q27	ASB2	P28482	MAPK1	S29	E27Q	27	Missense	proximal	-2	no	14.784	14.170	EPSD	COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q96Q27	ASB2	P28482	MAPK1	S29	M35V	35	Missense	distal	6	no	14.784	15.002	EPSD	COSMIC;GDSC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q96Q27	ASB2	P28482	MAPK1	S199	R200P	200	Missense	proximal	1	no	4.221	13.875	EPSD	COSMIC	8.102	Gain
CMGC_MAPK_ERK1_MAPK1_ST	Q96Q27	ASB2	P28482	MAPK1	S323	R316H	316	Missense	distal	-7	no	15.039	15.028	PhosphoSitePlus	COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q96Q27	ASB2	P28482	MAPK1	S323	V322I	322	Missense	proximal	-1	no	15.039	14.999	PhosphoSitePlus	COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q96Q27	ASB2	P28482	MAPK1	S323	P324S	324	Missense	proximal	1	no	15.039	5.644	PhosphoSitePlus	COSMIC	8.102	Loss
CMGC_MAPK_ERK1_MAPK1_ST	Q07820	MCL1	P28482	MAPK1	S64	G58S	58	Missense	distal	-6	no	13.591	13.608	EPSD	COSMIC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q07820	MCL1	P28482	MAPK1	S64	G59E	59	Missense	distal	-5	no	13.591	13.549	EPSD	COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q07820	MCL1	P28482	MAPK1	S64	P65L	65	Missense	proximal	1	no	13.591	4.782	EPSD	COSMIC	8.102	Loss
CMGC_MAPK_ERK1_MAPK1_ST	Q07820	MCL1	P28482	MAPK1	T70	D72G	72	Missense	proximal	2	no	13.123	13.158	EPSD	COSMIC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q07820	MCL1	P28482	MAPK1	T70	P65L	65	Missense	distal	-5	no	13.123	13.272	EPSD	COSMIC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q07820	MCL1	P28482	MAPK1	T70	A77V	77	Missense	distal	7	no	13.123	13.225	EPSD	COSMIC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q07820	MCL1	P28482	MAPK1	T92	P93R	93	Missense	proximal	1	no	13.543	3.889	EPSD	COSMIC	8.102	Loss
CMGC_MAPK_ERK1_MAPK1_ST	Q07820	MCL1	P28482	MAPK1	T92	F99L	99	Missense	distal	7	no	13.543	13.484	EPSD	COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q07820	MCL1	P28482	MAPK1	T92	P87L	87	Missense	distal	-5	no	13.543	13.692	EPSD	COSMIC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q07820	MCL1	P28482	MAPK1	S121	L126M	126	Missense	distal	5	no	14.752	14.779	EPSD	COSMIC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q07820	MCL1	P28482	MAPK1	S121	A116P	116	Missense	distal	-5	no	14.752	14.627	EPSD	COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q07820	MCL1	P28482	MAPK1	S121	P122L	122	Missense	proximal	1	no	14.752	5.943	EPSD	COSMIC	8.102	Loss
CMGC_MAPK_ERK1_MAPK1_ST	Q07820	MCL1	P28482	MAPK1	T163	E169K	169	Missense	distal	6	no	17.184	17.207	PhosphoSitePlus	COSMIC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q07820	MCL1	P28482	MAPK1	T163	P161F	161	Missense	proximal	-2	no	17.184	14.544	PhosphoSitePlus	COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q07820	MCL1	P28482	MAPK1	T163	P161H	161	Missense	proximal	-2	no	17.184	14.429	PhosphoSitePlus	COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q07820	MCL1	P28482	MAPK1	T163	G158R	158	Missense	distal	-5	no	17.184	17.164	PhosphoSitePlus	COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q07820	MCL1	P28482	MAPK1	T163	G158D	158	Missense	distal	-5	no	17.184	17.186	PhosphoSitePlus	COSMIC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P68400	CSNK2A1	P28482	MAPK1	T13	R19T	19	Missense	distal	6	no	8.190	8.086	EPSD	COSMIC	8.102	Loss
CMGC_MAPK_ERK1_MAPK1_ST	P68400	CSNK2A1	P28482	MAPK1	T17	R21G	21	Missense	distal	4	no	9.899	9.873	EPSD	COSMIC;CCLE	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P68400	CSNK2A1	P28482	MAPK1	T17	R19T	19	Missense	proximal	2	no	9.899	9.735	EPSD	COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P68400	CSNK2A1	P28482	MAPK1	T360	T360I	360	Missense	central	0	yes	15.211	0.000	EPSD;PhosphoSitePlus	COSMIC	8.102	Loss
CMGC_MAPK_ERK1_MAPK1_ST	P68400	CSNK2A1	P28482	MAPK1	T360	L364R	364	Missense	distal	4	no	15.211	15.298	EPSD;PhosphoSitePlus	COSMIC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P68400	CSNK2A1	P28482	MAPK1	T360	P361H	361	Missense	proximal	1	no	15.211	7.387	EPSD;PhosphoSitePlus	COSMIC	8.102	Loss
CMGC_MAPK_ERK1_MAPK1_ST	P68400	CSNK2A1	P28482	MAPK1	S362	T360I	360	Missense	proximal	-2	no	14.277	15.082	PhosphoSitePlus;EPSD	COSMIC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P68400	CSNK2A1	P28482	MAPK1	S362	L364R	364	Missense	proximal	2	no	14.277	14.538	PhosphoSitePlus;EPSD	COSMIC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P68400	CSNK2A1	P28482	MAPK1	S362	A368D	368	Missense	distal	6	no	14.277	14.528	PhosphoSitePlus;EPSD	COSMIC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P68400	CSNK2A1	P28482	MAPK1	S362	P361H	361	Missense	proximal	-1	no	14.277	14.234	PhosphoSitePlus;EPSD	COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P68400	CSNK2A1	P28482	MAPK1	S370	L364R	364	Missense	distal	-6	no	16.132	16.232	EPSD	COSMIC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P68400	CSNK2A1	P28482	MAPK1	S370	A368D	368	Missense	proximal	-2	no	16.132	15.977	EPSD	COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q9BTL3	RAMAC	P28482	MAPK1	S36	P34S	34	Missense	proximal	-2	no	19.367	16.532	PhosphoSitePlus	COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q9BTL3	RAMAC	P28482	MAPK1	S36	R32H	32	Missense	distal	-4	no	19.367	19.215	PhosphoSitePlus	COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q9BTL3	RAMAC	P28482	MAPK1	S36	R32C	32	Missense	distal	-4	no	19.367	18.728	PhosphoSitePlus	COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q9UKX7	NUP50	P28482	MAPK1	T184	N178Y	178	Missense	distal	-6	no	9.382	9.265	EPSD	COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q9UKX7	NUP50	P28482	MAPK1	T184	T184A	184	Missense	central	0	yes	9.382	0.000	EPSD	COSMIC	8.102	Loss
CMGC_MAPK_ERK1_MAPK1_ST	Q9UKX7	NUP50	P28482	MAPK1	S221	L224F	224	Missense	distal	3	no	14.761	14.803	EPSD;PhosphoSitePlus	COSMIC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q9UKX7	NUP50	P28482	MAPK1	T246	M251V	251	Missense	distal	5	no	12.671	12.733	EPSD	COSMIC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q9UKX7	NUP50	P28482	MAPK1	S270	G274S	274	Missense	distal	4	no	8.071	8.120	EPSD	COSMIC;CCLE	8.102	Gain
CMGC_MAPK_ERK1_MAPK1_ST	Q9UKX7	NUP50	P28482	MAPK1	S314	T307I	307	Missense	distal	-7	no	8.204	8.190	EPSD	COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q9UKX7	NUP50	P28482	MAPK1	S314	P316Q	316	Missense	proximal	2	no	8.204	8.026	EPSD	COSMIC	8.102	Loss
CMGC_MAPK_ERK1_MAPK1_ST	Q9UKX7	NUP50	P28482	MAPK1	S315	P316Q	316	Missense	proximal	1	no	15.287	6.793	PhosphoSitePlus;EPSD	COSMIC	8.102	Loss
CMGC_MAPK_ERK1_MAPK1_ST	Q08493	PDE4C	P28482	MAPK1	S62	P65L	65	Missense	distal	3	no	14.394	14.484	EPSD	COSMIC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q08493	PDE4C	P28482	MAPK1	S62	R57W	57	Missense	distal	-5	no	14.394	14.670	EPSD	COSMIC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q08493	PDE4C	P28482	MAPK1	S62	G55W	55	Missense	distal	-7	no	14.394	14.357	EPSD	COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q08493	PDE4C	P28482	MAPK1	S62	P65S	65	Missense	distal	3	no	14.394	14.463	EPSD	COSMIC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q08493	PDE4C	P28482	MAPK1	S100	G102V	102	Missense	proximal	2	no	13.736	13.664	EPSD	COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q08493	PDE4C	P28482	MAPK1	S100	P101R	101	Missense	proximal	1	no	13.736	4.082	EPSD	COSMIC	8.102	Loss
CMGC_MAPK_ERK1_MAPK1_ST	Q08493	PDE4C	P28482	MAPK1	S100	R105W	105	Missense	distal	5	no	13.736	13.207	EPSD	COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q08493	PDE4C	P28482	MAPK1	S100	S99L	99	Missense	proximal	-1	no	13.736	13.719	EPSD	COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q08493	PDE4C	P28482	MAPK1	S114	R116Q	116	Missense	proximal	2	no	8.476	8.185	EPSD	COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q08493	PDE4C	P28482	MAPK1	S114	R116W	116	Missense	proximal	2	no	8.476	8.108	EPSD	COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q08493	PDE4C	P28482	MAPK1	S114	P112Q	112	Missense	proximal	-2	no	8.476	5.483	EPSD	COSMIC	8.102	Loss
CMGC_MAPK_ERK1_MAPK1_ST	Q08493	PDE4C	P28482	MAPK1	S131	S131L	131	Missense	central	0	yes	14.514	0.000	EPSD	COSMIC	8.102	Loss
CMGC_MAPK_ERK1_MAPK1_ST	Q08493	PDE4C	P28482	MAPK1	S131	R137L	137	Missense	distal	6	no	14.514	14.214	EPSD	COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q08493	PDE4C	P28482	MAPK1	T265	E272D	272	Missense	distal	7	no	8.317	8.373	EPSD	COSMIC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q08493	PDE4C	P28482	MAPK1	T265	L267V	267	Missense	proximal	2	no	8.317	8.411	EPSD	COSMIC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q08493	PDE4C	P28482	MAPK1	S487	L488P	488	Missense	proximal	1	no	5.715	14.525	EPSD	COSMIC	8.102	Gain
CMGC_MAPK_ERK1_MAPK1_ST	Q08493	PDE4C	P28482	MAPK1	S641	Y634H	634	Missense	distal	-7	no	17.959	17.978	EPSD	COSMIC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q08493	PDE4C	P28482	MAPK1	S641	T646I	646	Missense	distal	5	no	17.959	17.715	EPSD	COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q96LC9	BMF	P28482	MAPK1	S64	R61Q	61	Missense	distal	-3	no	9.562	9.285	EPSD	COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q96LC9	BMF	P28482	MAPK1	S64	K68N	68	Missense	distal	4	no	9.562	9.537	EPSD	COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q96LC9	BMF	P28482	MAPK1	S64	G59D	59	Missense	distal	-5	no	9.562	9.564	EPSD	COSMIC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q96LC9	BMF	P28482	MAPK1	S74	K68N	68	Missense	distal	-6	no	15.634	15.626	PhosphoSitePlus;EPSD	COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q96LC9	BMF	P28482	MAPK1	S109	A108P	108	Missense	proximal	-1	no	9.393	9.429	EPSD	COSMIC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q15746	MYLK	P28482	MAPK1	S16	S16C	16	Missense	central	0	yes	8.118	0.000	EPSD	COSMIC	8.102	Loss
CMGC_MAPK_ERK1_MAPK1_ST	Q15746	MYLK	P28482	MAPK1	S16	R23I	23	Missense	distal	7	no	8.118	8.662	EPSD	COSMIC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q15746	MYLK	P28482	MAPK1	S16	P21L	21	Missense	distal	5	no	8.118	7.904	EPSD	COSMIC	8.102	Loss
CMGC_MAPK_ERK1_MAPK1_ST	Q15746	MYLK	P28482	MAPK1	S16	S13F	13	Missense	distal	-3	no	8.118	7.885	EPSD	COSMIC;CCLE	8.102	Loss
CMGC_MAPK_ERK1_MAPK1_ST	Q15746	MYLK	P28482	MAPK1	S16	H11R	11	Missense	distal	-5	no	8.118	8.040	EPSD	COSMIC	8.102	Loss
CMGC_MAPK_ERK1_MAPK1_ST	Q15746	MYLK	P28482	MAPK1	S299	G303C	303	Missense	distal	4	no	12.013	11.780	EPSD	COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q15746	MYLK	P28482	MAPK1	S299	S298Y	298	Missense	proximal	-1	no	12.013	11.981	EPSD	COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q15746	MYLK	P28482	MAPK1	S305	G303C	303	Missense	proximal	-2	no	13.986	13.413	EPSD	COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q15746	MYLK	P28482	MAPK1	S305	S312N	312	Missense	distal	7	no	13.986	13.969	EPSD	COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q15746	MYLK	P28482	MAPK1	S305	S298Y	298	Missense	distal	-7	no	13.986	13.955	EPSD	COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q15746	MYLK	P28482	MAPK1	S328	D327N	327	Missense	proximal	-1	no	14.314	14.375	EPSD	COSMIC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q15746	MYLK	P28482	MAPK1	S328	E323K	323	Missense	distal	-5	no	14.314	14.291	EPSD	COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q15746	MYLK	P28482	MAPK1	S365	P359L	359	Missense	distal	-6	no	15.138	15.046	EPSD	COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q15746	MYLK	P28482	MAPK1	S515	D522Y	522	Missense	distal	7	no	9.945	10.467	EPSD	COSMIC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q15746	MYLK	P28482	MAPK1	S515	S515P	515	Missense	central	0	yes	9.945	0.000	EPSD	COSMIC	8.102	Loss
CMGC_MAPK_ERK1_MAPK1_ST	Q15746	MYLK	P28482	MAPK1	S947	Q949R	949	Missense	proximal	2	no	14.753	15.044	EPSD	COSMIC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q15746	MYLK	P28482	MAPK1	S947	E940K	940	Missense	distal	-7	no	14.753	14.746	EPSD	COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q15746	MYLK	P28482	MAPK1	S947	P948S	948	Missense	proximal	1	no	14.753	5.358	EPSD	COSMIC;GDSC;CCLE	8.102	Loss
CMGC_MAPK_ERK1_MAPK1_ST	Q15746	MYLK	P28482	MAPK1	S947	S947N	947	Missense	central	0	yes	14.753	0.000	EPSD	COSMIC	8.102	Loss
CMGC_MAPK_ERK1_MAPK1_ST	Q15746	MYLK	P28482	MAPK1	T978	V971G	971	Missense	distal	-7	no	16.073	16.074	EPSD	COSMIC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q15746	MYLK	P28482	MAPK1	T978	P976L	976	Missense	proximal	-2	no	16.073	14.156	EPSD	COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q15746	MYLK	P28482	MAPK1	T1230	P1232L	1232	Missense	proximal	2	no	14.393	14.246	EPSD	COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q15746	MYLK	P28482	MAPK1	T1337	I1343T	1343	Missense	distal	6	no	11.797	12.254	EPSD	COSMIC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q15746	MYLK	P28482	MAPK1	T1337	P1338S	1338	Missense	proximal	1	no	11.797	2.402	EPSD	COSMIC	8.102	Loss
CMGC_MAPK_ERK1_MAPK1_ST	Q15746	MYLK	P28482	MAPK1	S1659	D1666N	1666	Missense	distal	7	no	12.634	12.620	EPSD	COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q15746	MYLK	P28482	MAPK1	S1776	P1777S	1777	Missense	proximal	1	no	12.880	3.485	EPSD	COSMIC	8.102	Loss
CMGC_MAPK_ERK1_MAPK1_ST	Q15746	MYLK	P28482	MAPK1	S1776	L1781F	1781	Missense	distal	5	no	12.880	12.914	EPSD	COSMIC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q15746	MYLK	P28482	MAPK1	S1779	P1777S	1777	Missense	proximal	-2	no	16.167	13.333	PhosphoSitePlus	COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q15746	MYLK	P28482	MAPK1	S1779	L1781F	1781	Missense	proximal	2	no	16.167	16.155	PhosphoSitePlus	COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	O75581	LRP6	P28482	MAPK1	S646	N651S	651	Missense	distal	5	no	8.517	8.590	EPSD	COSMIC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	O75581	LRP6	P28482	MAPK1	S1490	S1490F	1490	Missense	central	0	yes	17.067	0.000	PhosphoSitePlus;EPSD	COSMIC	8.102	Loss
CMGC_MAPK_ERK1_MAPK1_ST	O75581	LRP6	P28482	MAPK1	S1490	S1496L	1496	Missense	distal	6	no	17.067	16.661	PhosphoSitePlus;EPSD	COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	O75581	LRP6	P28482	MAPK1	T1493	S1490F	1490	Missense	distal	-3	no	8.374	8.141	EPSD	COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	O75581	LRP6	P28482	MAPK1	T1493	S1496L	1496	Missense	distal	3	no	8.374	8.394	EPSD	COSMIC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	O75581	LRP6	P28482	MAPK1	S1508	S1508R	1508	Missense	central	0	yes	14.168	0.000	EPSD	COSMIC	8.102	Loss
CMGC_MAPK_ERK1_MAPK1_ST	O75581	LRP6	P28482	MAPK1	S1508	S1514A	1514	Missense	distal	6	no	14.168	13.871	EPSD	COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	O75581	LRP6	P28482	MAPK1	S1508	F1502C	1502	Missense	distal	-6	no	14.168	14.111	EPSD	COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	O75581	LRP6	P28482	MAPK1	S1508	N1507K	1507	Missense	proximal	-1	no	14.168	14.175	EPSD	COSMIC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	O75581	LRP6	P28482	MAPK1	S1521	P1528H	1528	Missense	distal	7	no	9.568	9.801	EPSD	COSMIC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	O75581	LRP6	P28482	MAPK1	S1521	Y1520C	1520	Missense	proximal	-1	no	9.568	9.521	EPSD	COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	O75581	LRP6	P28482	MAPK1	S1521	S1514A	1514	Missense	distal	-7	no	9.568	9.569	EPSD	COSMIC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	O75581	LRP6	P28482	MAPK1	S1521	R1523Q	1523	Missense	proximal	2	no	9.568	9.276	EPSD	COSMIC;GDSC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	O75581	LRP6	P28482	MAPK1	T1530	P1528H	1528	Missense	proximal	-2	no	16.491	13.736	EPSD	COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	O75581	LRP6	P28482	MAPK1	T1530	R1523Q	1523	Missense	distal	-7	no	16.491	16.499	EPSD	COSMIC;GDSC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	O75581	LRP6	P28482	MAPK1	T1572	P1571S	1571	Missense	proximal	-1	no	16.928	16.885	EPSD;PhosphoSitePlus	COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	O75581	LRP6	P28482	MAPK1	S1575	E1581Q	1581	Missense	distal	6	no	9.163	8.842	EPSD	COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	O75581	LRP6	P28482	MAPK1	S1575	P1571S	1571	Missense	distal	-4	no	9.163	9.079	EPSD	COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	O75581	LRP6	P28482	MAPK1	S1590	P1589R	1589	Missense	proximal	-1	no	18.421	18.401	EPSD	COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	O75581	LRP6	P28482	MAPK1	S1607	H1600Q	1600	Missense	distal	-7	no	18.829	18.848	EPSD	COSMIC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	O75581	LRP6	P28482	MAPK1	S1607	P1604L	1604	Missense	distal	-3	no	18.829	18.445	EPSD	COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q02447	SP3	P28482	MAPK1	S73	D77H	77	Missense	distal	4	no	15.704	15.637	PhosphoSitePlus	COSMIC;CCLE	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q02447	SP3	P28482	MAPK1	S73	D77E	77	Missense	distal	4	no	15.704	15.774	PhosphoSitePlus	COSMIC;CCLE	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q02447	SP3	P28482	MAPK1	T115	S113T	113	Missense	proximal	-2	no	11.451	11.586	EPSD	COSMIC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q02447	SP3	P28482	MAPK1	S317	I320V	320	Missense	distal	3	no	14.614	14.544	EPSD	COSMIC;GDSC;CCLE	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q02447	SP3	P28482	MAPK1	S317	R315Q	315	Missense	proximal	-2	no	14.614	13.439	EPSD	COSMIC;GDSC;CCLE	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q02447	SP3	P28482	MAPK1	S317	R315L	315	Missense	proximal	-2	no	14.614	14.515	EPSD	COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q02447	SP3	P28482	MAPK1	S317	T323S	323	Missense	distal	6	no	14.614	14.824	EPSD	COSMIC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q02447	SP3	P28482	MAPK1	S317	R311K	311	Missense	distal	-6	no	14.614	14.591	EPSD	COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q02447	SP3	P28482	MAPK1	S317	R315P	315	Missense	proximal	-2	no	14.614	16.433	EPSD	COSMIC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q8IX03	WWC1	P28482	MAPK1	S358	G365W	365	Missense	distal	7	no	15.100	16.007	EPSD	COSMIC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q8IX03	WWC1	P28482	MAPK1	S358	R360H	360	Missense	proximal	2	no	15.100	14.857	EPSD	COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q8IX03	WWC1	P28482	MAPK1	S438	S434F	434	Missense	distal	-4	no	14.144	13.883	EPSD	COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q8IX03	WWC1	P28482	MAPK1	S441	S434F	434	Missense	distal	-7	no	9.221	9.200	EPSD	COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q8IX03	WWC1	P28482	MAPK1	S441	S448Y	448	Missense	distal	7	no	9.221	9.738	EPSD	COSMIC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q8IX03	WWC1	P28482	MAPK1	T527	L521V	521	Missense	distal	-6	no	15.324	15.330	EPSD	COSMIC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q8IX03	WWC1	P28482	MAPK1	S876	E873K	873	Missense	distal	-3	no	13.752	13.674	EPSD	COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q8IX03	WWC1	P28482	MAPK1	S876	D869H	869	Missense	distal	-7	no	13.752	13.739	EPSD	COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q8IX03	WWC1	P28482	MAPK1	S876	G881E	881	Missense	distal	5	no	13.752	13.727	EPSD	COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q8IX03	WWC1	P28482	MAPK1	S876	G881V	881	Missense	distal	5	no	13.752	13.629	EPSD	COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q8IX03	WWC1	P28482	MAPK1	T895	P900T	900	Missense	distal	5	no	12.565	12.509	EPSD	COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q8IX03	WWC1	P28482	MAPK1	T895	P898L	898	Missense	distal	3	no	12.565	12.654	EPSD	COSMIC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q8IX03	WWC1	P28482	MAPK1	T895	P900S	900	Missense	distal	5	no	12.565	12.583	EPSD	COSMIC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q8IX03	WWC1	P28482	MAPK1	T895	P896L	896	Missense	proximal	1	no	12.565	3.755	EPSD	COSMIC	8.102	Loss
CMGC_MAPK_ERK1_MAPK1_ST	Q8IX03	WWC1	P28482	MAPK1	S899	P900T	900	Missense	proximal	1	no	14.356	5.858	EPSD	COSMIC	8.102	Loss
CMGC_MAPK_ERK1_MAPK1_ST	Q8IX03	WWC1	P28482	MAPK1	S899	P898L	898	Missense	proximal	-1	no	14.356	14.296	EPSD	COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q8IX03	WWC1	P28482	MAPK1	S899	P900S	900	Missense	proximal	1	no	14.356	4.961	EPSD	COSMIC	8.102	Loss
CMGC_MAPK_ERK1_MAPK1_ST	Q8IX03	WWC1	P28482	MAPK1	S899	P896L	896	Missense	distal	-3	no	14.356	13.973	EPSD	COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q8IX03	WWC1	P28482	MAPK1	T912	P913S	913	Missense	proximal	1	no	12.850	3.455	EPSD	COSMIC	8.102	Loss
CMGC_MAPK_ERK1_MAPK1_ST	Q8IX03	WWC1	P28482	MAPK1	S931	K928Q	928	Missense	distal	-3	no	13.632	13.593	EPSD	COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P11362	FGFR1	P28482	MAPK1	S447	R448Q	448	Missense	proximal	1	no	6.959	8.120	EPSD	COSMIC	8.102	Gain
CMGC_MAPK_ERK1_MAPK1_ST	P11362	FGFR1	P28482	MAPK1	S450	S451F	451	Missense	proximal	1	no	6.763	9.588	EPSD	COSMIC	8.102	Gain
CMGC_MAPK_ERK1_MAPK1_ST	P11362	FGFR1	P28482	MAPK1	T454	S451F	451	Missense	distal	-3	no	12.097	11.864	EPSD	COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P11362	FGFR1	P28482	MAPK1	T454	R448Q	448	Missense	distal	-6	no	12.097	12.073	EPSD	COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P11362	FGFR1	P28482	MAPK1	T454	S451C	451	Missense	distal	-3	no	12.097	11.570	EPSD	COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P11362	FGFR1	P28482	MAPK1	T454	G459R	459	Missense	distal	5	no	12.097	12.147	EPSD	COSMIC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P11362	FGFR1	P28482	MAPK1	T454	T454N	454	Missense	central	0	yes	12.097	0.000	EPSD	COSMIC	8.102	Loss
CMGC_MAPK_ERK1_MAPK1_ST	P11362	FGFR1	P28482	MAPK1	T454	S447P	447	Missense	distal	-7	no	12.097	12.101	EPSD	COSMIC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P11362	FGFR1	P28482	MAPK1	T454	M456I	456	Missense	proximal	2	no	12.097	12.117	EPSD	COSMIC;GDSC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P11362	FGFR1	P28482	MAPK1	T454	M456V	456	Missense	proximal	2	no	12.097	12.234	EPSD	COSMIC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P11362	FGFR1	P28482	MAPK1	T454	S447L	447	Missense	distal	-7	no	12.097	12.089	EPSD	COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P11362	FGFR1	P28482	MAPK1	T454	R448L	448	Missense	distal	-6	no	12.097	11.997	EPSD	COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P11362	FGFR1	P28482	MAPK1	T454	L457R	457	Missense	distal	3	no	12.097	12.053	EPSD	COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P11362	FGFR1	P28482	MAPK1	S777	S779C	779	Missense	proximal	2	no	14.411	14.179	PhosphoSitePlus	COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P11362	FGFR1	P28482	MAPK1	S777	R784Q	784	Missense	distal	7	no	14.411	14.526	PhosphoSitePlus	COSMIC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P11362	FGFR1	P28482	MAPK1	S777	R784W	784	Missense	distal	7	no	14.411	15.382	PhosphoSitePlus	COSMIC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P11362	FGFR1	P28482	MAPK1	S777	P772S	772	Missense	distal	-5	no	14.411	14.485	PhosphoSitePlus	COSMIC;GDSC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P11362	FGFR1	P28482	MAPK1	S777	D782N	782	Missense	distal	5	no	14.411	14.313	PhosphoSitePlus	COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P11362	FGFR1	P28482	MAPK1	S777	P772H	772	Missense	distal	-5	no	14.411	14.535	PhosphoSitePlus	COSMIC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P11362	FGFR1	P28482	MAPK1	S779	S779C	779	Missense	central	0	yes	8.552	0.000	EPSD	COSMIC	8.102	Loss
CMGC_MAPK_ERK1_MAPK1_ST	P11362	FGFR1	P28482	MAPK1	S779	R784Q	784	Missense	distal	5	no	8.552	8.381	EPSD	COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P11362	FGFR1	P28482	MAPK1	S779	R784W	784	Missense	distal	5	no	8.552	8.023	EPSD	COSMIC	8.102	Loss
CMGC_MAPK_ERK1_MAPK1_ST	P11362	FGFR1	P28482	MAPK1	S779	P772S	772	Missense	distal	-7	no	8.552	8.547	EPSD	COSMIC;GDSC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P11362	FGFR1	P28482	MAPK1	S779	D782N	782	Missense	distal	3	no	8.552	8.456	EPSD	COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P11362	FGFR1	P28482	MAPK1	S779	P772H	772	Missense	distal	-7	no	8.552	8.535	EPSD	COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P11362	FGFR1	P28482	MAPK1	S789	S790P	790	Missense	proximal	1	no	3.219	12.614	EPSD	COSMIC	8.102	Gain
CMGC_MAPK_ERK1_MAPK1_ST	P11362	FGFR1	P28482	MAPK1	S797	E803K	803	Missense	distal	6	no	8.407	8.430	EPSD	COSMIC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P11362	FGFR1	P28482	MAPK1	S797	G791E	791	Missense	distal	-6	no	8.407	8.461	EPSD	COSMIC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P11362	FGFR1	P28482	MAPK1	S797	S794F	794	Missense	distal	-3	no	8.407	8.175	EPSD	COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P11362	FGFR1	P28482	MAPK1	S797	P800L	800	Missense	distal	3	no	8.407	8.497	EPSD	COSMIC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P11362	FGFR1	P28482	MAPK1	S797	V795I	795	Missense	proximal	-2	no	8.407	8.385	EPSD	COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P11362	FGFR1	P28482	MAPK1	S797	H798Y	798	Missense	proximal	1	no	8.407	9.222	EPSD	COSMIC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P11362	FGFR1	P28482	MAPK1	S797	E804K	804	Missense	distal	7	no	8.407	8.415	EPSD	COSMIC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P11362	FGFR1	P28482	MAPK1	S797	S790P	790	Missense	distal	-7	no	8.407	8.411	EPSD	COSMIC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P01106	MYC	P28482	MAPK1	T58	P57S	57	Missense	proximal	-1	no	15.566	15.523	EPSD;PhosphoSitePlus	COSMIC;CCLE	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P01106	MYC	P28482	MAPK1	T58	S62P	62	Missense	distal	4	no	15.566	15.577	EPSD;PhosphoSitePlus	COSMIC;CCLE	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P01106	MYC	P28482	MAPK1	T58	P59L	59	Missense	proximal	1	no	15.566	6.757	EPSD;PhosphoSitePlus	COSMIC;CCLE	8.102	Loss
CMGC_MAPK_ERK1_MAPK1_ST	P01106	MYC	P28482	MAPK1	T58	T58N	58	Missense	central	0	yes	15.566	0.000	EPSD;PhosphoSitePlus	COSMIC;CCLE	8.102	Loss
CMGC_MAPK_ERK1_MAPK1_ST	P01106	MYC	P28482	MAPK1	T58	P60H	60	Missense	proximal	2	no	15.566	15.437	EPSD;PhosphoSitePlus	COSMIC;CCLE	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P01106	MYC	P28482	MAPK1	T58	P63L	63	Missense	distal	5	no	15.566	15.353	EPSD;PhosphoSitePlus	COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P01106	MYC	P28482	MAPK1	T58	P63H	63	Missense	distal	5	no	15.566	15.439	EPSD;PhosphoSitePlus	COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P01106	MYC	P28482	MAPK1	T58	T58A	58	Missense	central	0	yes	15.566	0.000	EPSD;PhosphoSitePlus	COSMIC;CCLE	8.102	Loss
CMGC_MAPK_ERK1_MAPK1_ST	P01106	MYC	P28482	MAPK1	T58	P59A	59	Missense	proximal	1	no	15.566	7.936	EPSD;PhosphoSitePlus	COSMIC;CCLE	8.102	Loss
CMGC_MAPK_ERK1_MAPK1_ST	P01106	MYC	P28482	MAPK1	T58	P59R	59	Missense	proximal	1	no	15.566	5.912	EPSD;PhosphoSitePlus	COSMIC	8.102	Loss
CMGC_MAPK_ERK1_MAPK1_ST	P01106	MYC	P28482	MAPK1	T58	P60A	60	Missense	proximal	2	no	15.566	15.437	EPSD;PhosphoSitePlus	COSMIC;CCLE	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P01106	MYC	P28482	MAPK1	T58	P57T	57	Missense	proximal	-1	no	15.566	15.524	EPSD;PhosphoSitePlus	COSMIC;CCLE	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P01106	MYC	P28482	MAPK1	T58	P59S	59	Missense	proximal	1	no	15.566	6.171	EPSD;PhosphoSitePlus	COSMIC;CCLE	8.102	Loss
CMGC_MAPK_ERK1_MAPK1_ST	P01106	MYC	P28482	MAPK1	T58	S62F	62	Missense	distal	4	no	15.566	15.389	EPSD;PhosphoSitePlus	COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P01106	MYC	P28482	MAPK1	T58	T58I	58	Missense	central	0	yes	15.566	0.000	EPSD;PhosphoSitePlus	COSMIC;CCLE	8.102	Loss
CMGC_MAPK_ERK1_MAPK1_ST	P01106	MYC	P28482	MAPK1	T58	T58P	58	Missense	central	0	yes	15.566	0.000	EPSD;PhosphoSitePlus	COSMIC	8.102	Loss
CMGC_MAPK_ERK1_MAPK1_ST	P01106	MYC	P28482	MAPK1	T58	S64R	64	Missense	distal	6	no	15.566	15.459	EPSD;PhosphoSitePlus	COSMIC;CCLE	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P01106	MYC	P28482	MAPK1	T58	P57L	57	Missense	proximal	-1	no	15.566	15.506	EPSD;PhosphoSitePlus	COSMIC;CCLE	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P01106	MYC	P28482	MAPK1	T58	P63S	63	Missense	distal	5	no	15.566	15.584	EPSD;PhosphoSitePlus	COSMIC;CCLE	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P01106	MYC	P28482	MAPK1	T58	P57F	57	Missense	proximal	-1	no	15.566	15.477	EPSD;PhosphoSitePlus	COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P01106	MYC	P28482	MAPK1	T58	P59Q	59	Missense	proximal	1	no	15.566	7.073	EPSD;PhosphoSitePlus	COSMIC;CCLE	8.102	Loss
CMGC_MAPK_ERK1_MAPK1_ST	P01106	MYC	P28482	MAPK1	T58	P59T	59	Missense	proximal	1	no	15.566	7.068	EPSD;PhosphoSitePlus	COSMIC	8.102	Loss
CMGC_MAPK_ERK1_MAPK1_ST	P01106	MYC	P28482	MAPK1	T58	P60S	60	Missense	proximal	2	no	15.566	15.539	EPSD;PhosphoSitePlus	COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P01106	MYC	P28482	MAPK1	T58	P63A	63	Missense	distal	5	no	15.566	15.425	EPSD;PhosphoSitePlus	COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P01106	MYC	P28482	MAPK1	T58	S64N	64	Missense	distal	6	no	15.566	15.470	EPSD;PhosphoSitePlus	COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P01106	MYC	P28482	MAPK1	T58	P60L	60	Missense	proximal	2	no	15.566	15.419	EPSD;PhosphoSitePlus	COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P01106	MYC	P28482	MAPK1	T58	P57A	57	Missense	proximal	-1	no	15.566	15.529	EPSD;PhosphoSitePlus	COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P01106	MYC	P28482	MAPK1	T58	L56V	56	Missense	proximal	-2	no	15.566	15.611	EPSD;PhosphoSitePlus	COSMIC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P01106	MYC	P28482	MAPK1	T58	P63R	63	Missense	distal	5	no	15.566	15.616	EPSD;PhosphoSitePlus	COSMIC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P01106	MYC	P28482	MAPK1	T58	L56M	56	Missense	proximal	-2	no	15.566	13.469	EPSD;PhosphoSitePlus	COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P01106	MYC	P28482	MAPK1	T58	P63T	63	Missense	distal	5	no	15.566	15.511	EPSD;PhosphoSitePlus	COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P01106	MYC	P28482	MAPK1	T58	S62A	62	Missense	distal	4	no	15.566	15.473	EPSD;PhosphoSitePlus	COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P01106	MYC	P28482	MAPK1	T58	P57R	57	Missense	proximal	-1	no	15.566	15.547	EPSD;PhosphoSitePlus	COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P01106	MYC	P28482	MAPK1	T58	P60T	60	Missense	proximal	2	no	15.566	15.516	EPSD;PhosphoSitePlus	COSMIC;CCLE	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P01106	MYC	P28482	MAPK1	T58	E54V	54	Missense	distal	-4	no	15.566	15.241	EPSD;PhosphoSitePlus	COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P01106	MYC	P28482	MAPK1	T58	S64T	64	Missense	distal	6	no	15.566	15.356	EPSD;PhosphoSitePlus	COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P01106	MYC	P28482	MAPK1	T58	R65C	65	Missense	distal	7	no	15.566	16.222	EPSD;PhosphoSitePlus	COSMIC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P01106	MYC	P28482	MAPK1	T58	L55P	55	Missense	distal	-3	no	15.566	15.950	EPSD;PhosphoSitePlus	COSMIC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P01106	MYC	P28482	MAPK1	T58	L55M	55	Missense	distal	-3	no	15.566	15.513	EPSD;PhosphoSitePlus	COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P01106	MYC	P28482	MAPK1	T58	E54A	54	Missense	distal	-4	no	15.566	15.302	EPSD;PhosphoSitePlus	COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P01106	MYC	P28482	MAPK1	S62	P57S	57	Missense	distal	-5	no	14.519	14.593	PhosphoSitePlus;EPSD	COSMIC;CCLE	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P01106	MYC	P28482	MAPK1	S62	S62P	62	Missense	central	0	yes	14.519	0.000	PhosphoSitePlus;EPSD	COSMIC;CCLE	8.102	Loss
CMGC_MAPK_ERK1_MAPK1_ST	P01106	MYC	P28482	MAPK1	S62	P59L	59	Missense	distal	-3	no	14.519	14.136	PhosphoSitePlus;EPSD	COSMIC;CCLE	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P01106	MYC	P28482	MAPK1	S62	T58N	58	Missense	distal	-4	no	14.519	14.790	PhosphoSitePlus;EPSD	COSMIC;CCLE	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P01106	MYC	P28482	MAPK1	S62	P60H	60	Missense	proximal	-2	no	14.519	11.764	PhosphoSitePlus;EPSD	COSMIC;CCLE	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P01106	MYC	P28482	MAPK1	S62	P63L	63	Missense	proximal	1	no	14.519	5.710	PhosphoSitePlus;EPSD	COSMIC	8.102	Loss
CMGC_MAPK_ERK1_MAPK1_ST	P01106	MYC	P28482	MAPK1	S62	P63H	63	Missense	proximal	1	no	14.519	6.696	PhosphoSitePlus;EPSD	COSMIC	8.102	Loss
CMGC_MAPK_ERK1_MAPK1_ST	P01106	MYC	P28482	MAPK1	S62	T58A	58	Missense	distal	-4	no	14.519	14.539	PhosphoSitePlus;EPSD	COSMIC;CCLE	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P01106	MYC	P28482	MAPK1	S62	P59A	59	Missense	distal	-3	no	14.519	14.152	PhosphoSitePlus;EPSD	COSMIC;CCLE	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P01106	MYC	P28482	MAPK1	S62	P59R	59	Missense	distal	-3	no	14.519	14.500	PhosphoSitePlus;EPSD	COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P01106	MYC	P28482	MAPK1	S62	P60A	60	Missense	proximal	-2	no	14.519	11.373	PhosphoSitePlus;EPSD	COSMIC;CCLE	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P01106	MYC	P28482	MAPK1	S62	P57T	57	Missense	distal	-5	no	14.519	14.622	PhosphoSitePlus;EPSD	COSMIC;CCLE	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P01106	MYC	P28482	MAPK1	S62	P59S	59	Missense	distal	-3	no	14.519	14.343	PhosphoSitePlus;EPSD	COSMIC;CCLE	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P01106	MYC	P28482	MAPK1	S62	S62F	62	Missense	central	0	yes	14.519	0.000	PhosphoSitePlus;EPSD	COSMIC	8.102	Loss
CMGC_MAPK_ERK1_MAPK1_ST	P01106	MYC	P28482	MAPK1	S62	T58I	58	Missense	distal	-4	no	14.519	14.162	PhosphoSitePlus;EPSD	COSMIC;CCLE	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P01106	MYC	P28482	MAPK1	S62	T58P	58	Missense	distal	-4	no	14.519	14.833	PhosphoSitePlus;EPSD	COSMIC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P01106	MYC	P28482	MAPK1	S62	S64R	64	Missense	proximal	2	no	14.519	14.660	PhosphoSitePlus;EPSD	COSMIC;CCLE	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P01106	MYC	P28482	MAPK1	S62	P57L	57	Missense	distal	-5	no	14.519	14.668	PhosphoSitePlus;EPSD	COSMIC;CCLE	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P01106	MYC	P28482	MAPK1	S62	P63S	63	Missense	proximal	1	no	14.519	5.124	PhosphoSitePlus;EPSD	COSMIC;CCLE	8.102	Loss
CMGC_MAPK_ERK1_MAPK1_ST	P01106	MYC	P28482	MAPK1	S62	R66H	66	Missense	distal	4	no	14.519	14.378	PhosphoSitePlus;EPSD	COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P01106	MYC	P28482	MAPK1	S62	P57F	57	Missense	distal	-5	no	14.519	14.682	PhosphoSitePlus;EPSD	COSMIC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P01106	MYC	P28482	MAPK1	S62	P59Q	59	Missense	distal	-3	no	14.519	14.223	PhosphoSitePlus;EPSD	COSMIC;CCLE	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P01106	MYC	P28482	MAPK1	S62	P59T	59	Missense	distal	-3	no	14.519	14.310	PhosphoSitePlus;EPSD	COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P01106	MYC	P28482	MAPK1	S62	P60S	60	Missense	proximal	-2	no	14.519	11.685	PhosphoSitePlus;EPSD	COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P01106	MYC	P28482	MAPK1	S62	P63A	63	Missense	proximal	1	no	14.519	6.889	PhosphoSitePlus;EPSD	COSMIC	8.102	Loss
CMGC_MAPK_ERK1_MAPK1_ST	P01106	MYC	P28482	MAPK1	S62	S64N	64	Missense	proximal	2	no	14.519	14.471	PhosphoSitePlus;EPSD	COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P01106	MYC	P28482	MAPK1	S62	P60L	60	Missense	proximal	-2	no	14.519	12.602	PhosphoSitePlus;EPSD	COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P01106	MYC	P28482	MAPK1	S62	P57A	57	Missense	distal	-5	no	14.519	14.644	PhosphoSitePlus;EPSD	COSMIC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P01106	MYC	P28482	MAPK1	S62	L56V	56	Missense	distal	-6	no	14.519	14.525	PhosphoSitePlus;EPSD	COSMIC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P01106	MYC	P28482	MAPK1	S62	P63R	63	Missense	proximal	1	no	14.519	4.865	PhosphoSitePlus;EPSD	COSMIC	8.102	Loss
CMGC_MAPK_ERK1_MAPK1_ST	P01106	MYC	P28482	MAPK1	S62	L56M	56	Missense	distal	-6	no	14.519	14.527	PhosphoSitePlus;EPSD	COSMIC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P01106	MYC	P28482	MAPK1	S62	L69V	69	Missense	distal	7	no	14.519	14.514	PhosphoSitePlus;EPSD	COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P01106	MYC	P28482	MAPK1	S62	P63T	63	Missense	proximal	1	no	14.519	6.021	PhosphoSitePlus;EPSD	COSMIC	8.102	Loss
CMGC_MAPK_ERK1_MAPK1_ST	P01106	MYC	P28482	MAPK1	S62	S67F	67	Missense	distal	5	no	14.519	14.322	PhosphoSitePlus;EPSD	COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P01106	MYC	P28482	MAPK1	S62	S62A	62	Missense	central	0	yes	14.519	0.000	PhosphoSitePlus;EPSD	COSMIC	8.102	Loss
CMGC_MAPK_ERK1_MAPK1_ST	P01106	MYC	P28482	MAPK1	S62	P57R	57	Missense	distal	-5	no	14.519	14.567	PhosphoSitePlus;EPSD	COSMIC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P01106	MYC	P28482	MAPK1	S62	L69P	69	Missense	distal	7	no	14.519	14.220	PhosphoSitePlus;EPSD	COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P01106	MYC	P28482	MAPK1	S62	P60T	60	Missense	proximal	-2	no	14.519	11.820	PhosphoSitePlus;EPSD	COSMIC;CCLE	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P01106	MYC	P28482	MAPK1	S62	L69F	69	Missense	distal	7	no	14.519	14.578	PhosphoSitePlus;EPSD	COSMIC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P01106	MYC	P28482	MAPK1	S62	S64T	64	Missense	proximal	2	no	14.519	14.497	PhosphoSitePlus;EPSD	COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P01106	MYC	P28482	MAPK1	S62	R65C	65	Missense	distal	3	no	14.519	14.646	PhosphoSitePlus;EPSD	COSMIC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P01106	MYC	P28482	MAPK1	S62	L55P	55	Missense	distal	-7	no	14.519	14.531	PhosphoSitePlus;EPSD	COSMIC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P01106	MYC	P28482	MAPK1	S62	L55M	55	Missense	distal	-7	no	14.519	14.510	PhosphoSitePlus;EPSD	COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P01106	MYC	P28482	MAPK1	S71	C70R	70	Missense	proximal	-1	no	14.405	14.507	EPSD	COSMIC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P01106	MYC	P28482	MAPK1	S71	S64R	64	Missense	distal	-7	no	14.405	14.404	EPSD	COSMIC;CCLE	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P01106	MYC	P28482	MAPK1	S71	R66H	66	Missense	distal	-5	no	14.405	14.482	EPSD	COSMIC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P01106	MYC	P28482	MAPK1	S71	A76V	76	Missense	distal	5	no	14.405	14.422	EPSD	COSMIC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P01106	MYC	P28482	MAPK1	S71	V77I	77	Missense	distal	6	no	14.405	13.953	EPSD	COSMIC;CCLE	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P01106	MYC	P28482	MAPK1	S71	S71L	71	Missense	central	0	yes	14.405	0.000	EPSD	COSMIC	8.102	Loss
CMGC_MAPK_ERK1_MAPK1_ST	P01106	MYC	P28482	MAPK1	S71	S64N	64	Missense	distal	-7	no	14.405	14.407	EPSD	COSMIC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P01106	MYC	P28482	MAPK1	S71	Y74N	74	Missense	distal	3	no	14.405	14.269	EPSD	COSMIC;CCLE	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P01106	MYC	P28482	MAPK1	S71	L69V	69	Missense	proximal	-2	no	14.405	14.449	EPSD	COSMIC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P01106	MYC	P28482	MAPK1	S71	V77G	77	Missense	distal	6	no	14.405	14.542	EPSD	COSMIC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P01106	MYC	P28482	MAPK1	S71	Y74H	74	Missense	distal	3	no	14.405	14.366	EPSD	COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P01106	MYC	P28482	MAPK1	S71	S67F	67	Missense	distal	-4	no	14.405	14.144	EPSD	COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P01106	MYC	P28482	MAPK1	S71	V75I	75	Missense	distal	4	no	14.405	14.338	EPSD	COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P01106	MYC	P28482	MAPK1	S71	L69P	69	Missense	proximal	-2	no	14.405	16.322	EPSD	COSMIC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P01106	MYC	P28482	MAPK1	S71	C70W	70	Missense	proximal	-1	no	14.405	14.406	EPSD	COSMIC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P01106	MYC	P28482	MAPK1	S71	S71W	71	Missense	central	0	yes	14.405	0.000	EPSD	COSMIC	8.102	Loss
CMGC_MAPK_ERK1_MAPK1_ST	P01106	MYC	P28482	MAPK1	S71	L69F	69	Missense	proximal	-2	no	14.405	13.682	EPSD	COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P01106	MYC	P28482	MAPK1	S71	S73P	73	Missense	proximal	2	no	14.405	14.433	EPSD	COSMIC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P01106	MYC	P28482	MAPK1	S71	S64T	64	Missense	distal	-7	no	14.405	14.392	EPSD	COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P01106	MYC	P28482	MAPK1	S71	R65C	65	Missense	distal	-6	no	14.405	14.230	EPSD	COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P01106	MYC	P28482	MAPK1	S71	P72F	72	Missense	proximal	1	no	14.405	7.835	EPSD	COSMIC	8.102	Loss
CMGC_MAPK_ERK1_MAPK1_ST	P01106	MYC	P28482	MAPK1	S71	P72R	72	Missense	proximal	1	no	14.405	4.750	EPSD	COSMIC	8.102	Loss
CMGC_MAPK_ERK1_MAPK1_ST	P01106	MYC	P28482	MAPK1	T78	S81F	81	Missense	distal	3	no	15.642	15.704	EPSD	COSMIC;CCLE	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P01106	MYC	P28482	MAPK1	T78	R83Q	83	Missense	distal	5	no	15.642	15.472	EPSD	COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P01106	MYC	P28482	MAPK1	T78	A76V	76	Missense	proximal	-2	no	15.642	16.916	EPSD	COSMIC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P01106	MYC	P28482	MAPK1	T78	V77I	77	Missense	proximal	-1	no	15.642	15.602	EPSD	COSMIC;CCLE	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P01106	MYC	P28482	MAPK1	T78	S71L	71	Missense	distal	-7	no	15.642	15.634	EPSD	COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P01106	MYC	P28482	MAPK1	T78	L82V	82	Missense	distal	4	no	15.642	15.652	EPSD	COSMIC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P01106	MYC	P28482	MAPK1	T78	G84R	84	Missense	distal	6	no	15.642	15.612	EPSD	COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P01106	MYC	P28482	MAPK1	T78	P79S	79	Missense	proximal	1	no	15.642	6.247	EPSD	COSMIC	8.102	Loss
CMGC_MAPK_ERK1_MAPK1_ST	P01106	MYC	P28482	MAPK1	T78	Y74N	74	Missense	distal	-4	no	15.642	16.272	EPSD	COSMIC;CCLE	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P01106	MYC	P28482	MAPK1	T78	F80L	80	Missense	proximal	2	no	15.642	15.654	EPSD	COSMIC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P01106	MYC	P28482	MAPK1	T78	D85Y	85	Missense	distal	7	no	15.642	16.163	EPSD	COSMIC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P01106	MYC	P28482	MAPK1	T78	V77G	77	Missense	proximal	-1	no	15.642	15.613	EPSD	COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P01106	MYC	P28482	MAPK1	T78	S81C	81	Missense	distal	3	no	15.642	15.745	EPSD	COSMIC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P01106	MYC	P28482	MAPK1	T78	Y74H	74	Missense	distal	-4	no	15.642	16.073	EPSD	COSMIC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P01106	MYC	P28482	MAPK1	T78	D85E	85	Missense	distal	7	no	15.642	15.586	EPSD	COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P01106	MYC	P28482	MAPK1	T78	V75I	75	Missense	distal	-3	no	15.642	15.508	EPSD	COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P01106	MYC	P28482	MAPK1	T78	S71W	71	Missense	distal	-7	no	15.642	15.590	EPSD	COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P01106	MYC	P28482	MAPK1	T78	L82H	82	Missense	distal	4	no	15.642	15.587	EPSD	COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P01106	MYC	P28482	MAPK1	T78	S73P	73	Missense	distal	-5	no	15.642	15.568	EPSD	COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P01106	MYC	P28482	MAPK1	T78	P72F	72	Missense	distal	-6	no	15.642	15.531	EPSD	COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P01106	MYC	P28482	MAPK1	T78	P72R	72	Missense	distal	-6	no	15.642	15.650	EPSD	COSMIC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P01106	MYC	P28482	MAPK1	S81	S81F	81	Missense	central	0	yes	8.464	0.000	EPSD	COSMIC;CCLE	8.102	Loss
CMGC_MAPK_ERK1_MAPK1_ST	P01106	MYC	P28482	MAPK1	S81	R83Q	83	Missense	proximal	2	no	8.464	8.172	EPSD	COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P01106	MYC	P28482	MAPK1	S81	G88D	88	Missense	distal	7	no	8.464	8.391	EPSD	COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P01106	MYC	P28482	MAPK1	S81	A76V	76	Missense	distal	-5	no	8.464	8.435	EPSD	COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P01106	MYC	P28482	MAPK1	S81	V77I	77	Missense	distal	-4	no	8.464	8.147	EPSD	COSMIC;CCLE	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P01106	MYC	P28482	MAPK1	S81	L82V	82	Missense	proximal	1	no	8.464	7.733	EPSD	COSMIC	8.102	Loss
CMGC_MAPK_ERK1_MAPK1_ST	P01106	MYC	P28482	MAPK1	S81	D87G	87	Missense	distal	6	no	8.464	8.432	EPSD	COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P01106	MYC	P28482	MAPK1	S81	G84R	84	Missense	distal	3	no	8.464	8.426	EPSD	COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P01106	MYC	P28482	MAPK1	S81	P79S	79	Missense	proximal	-2	no	8.464	5.629	EPSD	COSMIC	8.102	Loss
CMGC_MAPK_ERK1_MAPK1_ST	P01106	MYC	P28482	MAPK1	S81	Y74N	74	Missense	distal	-7	no	8.464	8.497	EPSD	COSMIC;CCLE	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P01106	MYC	P28482	MAPK1	S81	G88V	88	Missense	distal	7	no	8.464	8.678	EPSD	COSMIC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P01106	MYC	P28482	MAPK1	S81	F80L	80	Missense	proximal	-1	no	8.464	8.493	EPSD	COSMIC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P01106	MYC	P28482	MAPK1	S81	D85Y	85	Missense	distal	4	no	8.464	8.366	EPSD	COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P01106	MYC	P28482	MAPK1	S81	N86T	86	Missense	distal	5	no	8.464	8.463	EPSD	COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P01106	MYC	P28482	MAPK1	S81	V77G	77	Missense	distal	-4	no	8.464	8.468	EPSD	COSMIC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P01106	MYC	P28482	MAPK1	S81	N86S	86	Missense	distal	5	no	8.464	8.536	EPSD	COSMIC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P01106	MYC	P28482	MAPK1	S81	S81C	81	Missense	central	0	yes	8.464	0.000	EPSD	COSMIC	8.102	Loss
CMGC_MAPK_ERK1_MAPK1_ST	P01106	MYC	P28482	MAPK1	S81	Y74H	74	Missense	distal	-7	no	8.464	8.483	EPSD	COSMIC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P01106	MYC	P28482	MAPK1	S81	D85E	85	Missense	distal	4	no	8.464	8.534	EPSD	COSMIC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P01106	MYC	P28482	MAPK1	S81	V75I	75	Missense	distal	-6	no	8.464	8.423	EPSD	COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P01106	MYC	P28482	MAPK1	S81	L82H	82	Missense	proximal	1	no	8.464	9.450	EPSD	COSMIC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P01106	MYC	P28482	MAPK1	S81	G88S	88	Missense	distal	7	no	8.464	8.395	EPSD	COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P01106	MYC	P28482	MAPK1	S161	K157T	157	Missense	distal	-4	no	14.115	13.813	EPSD	COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P01106	MYC	P28482	MAPK1	S161	A155S	155	Missense	distal	-6	no	14.115	14.128	EPSD	COSMIC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P01106	MYC	P28482	MAPK1	S161	K157N	157	Missense	distal	-4	no	14.115	14.084	EPSD	COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P01106	MYC	P28482	MAPK1	S161	A155T	155	Missense	distal	-6	no	14.115	14.105	EPSD	COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P01106	MYC	P28482	MAPK1	S161	N163K	163	Missense	proximal	2	no	14.115	14.124	EPSD	COSMIC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P01106	MYC	P28482	MAPK1	S161	P162R	162	Missense	proximal	1	no	14.115	4.461	EPSD	COSMIC	8.102	Loss
CMGC_MAPK_ERK1_MAPK1_ST	P01106	MYC	P28482	MAPK1	S161	A154T	154	Missense	distal	-7	no	14.115	14.101	EPSD	COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P01106	MYC	P28482	MAPK1	S161	G160D	160	Missense	proximal	-1	no	14.115	14.114	EPSD	COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P01106	MYC	P28482	MAPK1	S161	S159N	159	Missense	proximal	-2	no	14.115	14.130	EPSD	COSMIC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P01106	MYC	P28482	MAPK1	S161	A165S	165	Missense	distal	4	no	14.115	14.209	EPSD	COSMIC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P01106	MYC	P28482	MAPK1	S161	A165T	165	Missense	distal	4	no	14.115	14.096	EPSD	COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P01106	MYC	P28482	MAPK1	S161	S159T	159	Missense	proximal	-2	no	14.115	14.250	EPSD	COSMIC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P01106	MYC	P28482	MAPK1	S161	D158G	158	Missense	distal	-3	no	14.115	14.055	EPSD	COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P01106	MYC	P28482	MAPK1	S161	R166H	166	Missense	distal	5	no	14.115	13.939	EPSD	COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P01106	MYC	P28482	MAPK1	S161	S161N	161	Missense	central	0	yes	14.115	0.000	EPSD	COSMIC	8.102	Loss
CMGC_MAPK_ERK1_MAPK1_ST	P01106	MYC	P28482	MAPK1	S161	R156G	156	Missense	distal	-5	no	14.115	14.136	EPSD	COSMIC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P01106	MYC	P28482	MAPK1	S161	A154G	154	Missense	distal	-7	no	14.115	14.100	EPSD	COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P01106	MYC	P28482	MAPK1	S161	S159R	159	Missense	proximal	-2	no	14.115	15.131	EPSD	COSMIC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P01106	MYC	P28482	MAPK1	S161	A165D	165	Missense	distal	4	no	14.115	14.112	EPSD	COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P01106	MYC	P28482	MAPK1	S204	P198S	198	Missense	distal	-6	no	12.836	12.809	EPSD	COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P01106	MYC	P28482	MAPK1	S204	S203R	203	Missense	proximal	-1	no	12.836	12.859	EPSD	COSMIC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P01106	MYC	P28482	MAPK1	S204	S203N	203	Missense	proximal	-1	no	12.836	12.885	EPSD	COSMIC;CCLE	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P01106	MYC	P28482	MAPK1	S204	Y197D	197	Missense	distal	-7	no	12.836	12.868	EPSD	COSMIC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P01106	MYC	P28482	MAPK1	S204	S203T	203	Missense	proximal	-1	no	12.836	12.837	EPSD	COSMIC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P01106	MYC	P28482	MAPK1	S204	S203I	203	Missense	proximal	-1	no	12.836	12.813	EPSD	COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P01106	MYC	P28482	MAPK1	S204	Q211R	211	Missense	distal	7	no	12.836	12.720	EPSD	COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P01106	MYC	P28482	MAPK1	S204	P205S	205	Missense	proximal	1	no	12.836	3.441	EPSD	COSMIC	8.102	Loss
CMGC_MAPK_ERK1_MAPK1_ST	P01106	MYC	P28482	MAPK1	S204	N200I	200	Missense	distal	-4	no	12.836	12.207	EPSD	COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P01106	MYC	P28482	MAPK1	S204	S204A	204	Missense	central	0	yes	12.836	0.000	EPSD	COSMIC	8.102	Loss
CMGC_MAPK_ERK1_MAPK1_ST	P01106	MYC	P28482	MAPK1	S204	S202T	202	Missense	proximal	-2	no	12.836	12.970	EPSD	COSMIC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P01106	MYC	P28482	MAPK1	S204	S207P	207	Missense	distal	3	no	12.836	12.766	EPSD	COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P01106	MYC	P28482	MAPK1	S281	S283F	283	Missense	proximal	2	no	14.078	13.946	EPSD	COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P01106	MYC	P28482	MAPK1	S281	S277L	277	Missense	distal	-4	no	14.078	13.858	EPSD	COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P01106	MYC	P28482	MAPK1	S281	H287Q	287	Missense	distal	6	no	14.078	14.096	EPSD	COSMIC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P01106	MYC	P28482	MAPK1	S281	S279C	279	Missense	proximal	-2	no	14.078	13.146	EPSD	COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P01106	MYC	P28482	MAPK1	S281	S283Y	283	Missense	proximal	2	no	14.078	13.910	EPSD	COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P01106	MYC	P28482	MAPK1	S281	P282A	282	Missense	proximal	1	no	14.078	6.448	EPSD	COSMIC	8.102	Loss
CMGC_MAPK_ERK1_MAPK1_ST	P01106	MYC	P28482	MAPK1	S281	G285E	285	Missense	distal	4	no	14.078	14.100	EPSD	COSMIC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P01106	MYC	P28482	MAPK1	S281	G280R	280	Missense	proximal	-1	no	14.078	14.113	EPSD	COSMIC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P01106	MYC	P28482	MAPK1	S281	G274D	274	Missense	distal	-7	no	14.078	14.093	EPSD	COSMIC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P01106	MYC	P28482	MAPK1	S281	S281F	281	Missense	central	0	yes	14.078	0.000	EPSD	COSMIC	8.102	Loss
CMGC_MAPK_ERK1_MAPK1_ST	P01106	MYC	P28482	MAPK1	S293	S293C	293	Missense	central	0	yes	17.657	0.000	EPSD	COSMIC	8.102	Loss
CMGC_MAPK_ERK1_MAPK1_ST	P01106	MYC	P28482	MAPK1	S293	C300Y	300	Missense	distal	7	no	17.657	17.516	EPSD	COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P01106	MYC	P28482	MAPK1	S293	P290T	290	Missense	distal	-3	no	17.657	17.448	EPSD	COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P01106	MYC	P28482	MAPK1	S293	H287Q	287	Missense	distal	-6	no	17.657	17.716	EPSD	COSMIC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P01106	MYC	P28482	MAPK1	S293	C300S	300	Missense	distal	7	no	17.657	16.998	EPSD	COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P01106	MYC	P28482	MAPK1	S293	L295V	295	Missense	proximal	2	no	17.657	17.751	EPSD	COSMIC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P01106	MYC	P28482	MAPK1	S293	P290H	290	Missense	distal	-3	no	17.657	17.308	EPSD	COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P01106	MYC	P28482	MAPK1	S293	L297F	297	Missense	distal	4	no	17.657	17.589	EPSD	COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P01106	MYC	P28482	MAPK1	S293	P290S	290	Missense	distal	-3	no	17.657	17.481	EPSD	COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P01106	MYC	P28482	MAPK1	S293	S293R	293	Missense	central	0	yes	17.657	0.000	EPSD	COSMIC	8.102	Loss
CMGC_MAPK_ERK1_MAPK1_ST	P01106	MYC	P28482	MAPK1	S293	V296F	296	Missense	distal	3	no	17.657	17.731	EPSD	COSMIC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P01106	MYC	P28482	MAPK1	T315	A321T	321	Missense	distal	6	no	8.026	8.112	EPSD	COSMIC	8.102	Gain
CMGC_MAPK_ERK1_MAPK1_ST	P01106	MYC	P28482	MAPK1	T315	K317R	317	Missense	proximal	2	no	8.026	8.207	EPSD	COSMIC	8.102	Gain
CMGC_MAPK_ERK1_MAPK1_ST	P01106	MYC	P28482	MAPK1	T315	A321V	321	Missense	distal	6	no	8.026	8.107	EPSD	COSMIC	8.102	Gain
CMGC_MAPK_ERK1_MAPK1_ST	P01106	MYC	P28482	MAPK1	S344	S347F	347	Missense	distal	3	no	13.324	13.386	EPSD	COSMIC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P01106	MYC	P28482	MAPK1	S344	E351K	351	Missense	distal	7	no	13.324	13.332	EPSD	COSMIC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P01106	MYC	P28482	MAPK1	S344	S337T	337	Missense	distal	-7	no	13.324	13.311	EPSD	COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P01106	MYC	P28482	MAPK1	S347	S347F	347	Missense	central	0	yes	9.418	0.000	EPSD	COSMIC	8.102	Loss
CMGC_MAPK_ERK1_MAPK1_ST	P01106	MYC	P28482	MAPK1	S347	V354D	354	Missense	distal	7	no	9.418	9.131	EPSD	COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P01106	MYC	P28482	MAPK1	S347	E351K	351	Missense	distal	4	no	9.418	9.432	EPSD	COSMIC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P01106	MYC	P28482	MAPK1	S347	E352G	352	Missense	distal	5	no	9.418	9.442	EPSD	COSMIC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P14784	IL2RB	P28482	MAPK1	S431	G436V	436	Missense	distal	5	no	13.075	12.951	EPSD	COSMIC;CCLE	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P14784	IL2RB	P28482	MAPK1	S458	R465K	465	Missense	distal	7	no	8.389	8.334	EPSD	COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P14784	IL2RB	P28482	MAPK1	S458	G451D	451	Missense	distal	-7	no	8.389	8.404	EPSD	COSMIC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P14784	IL2RB	P28482	MAPK1	T476	P474H	474	Missense	proximal	-2	no	15.778	13.023	PhosphoSitePlus	COSMIC;GDSC;CCLE	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P14784	IL2RB	P28482	MAPK1	T533	S538F	538	Missense	distal	5	no	8.864	8.667	EPSD	COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P14784	IL2RB	P28482	MAPK1	T533	R528H	528	Missense	distal	-5	no	8.864	8.941	EPSD	COSMIC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P14784	IL2RB	P28482	MAPK1	T533	A527S	527	Missense	distal	-6	no	8.864	8.877	EPSD	COSMIC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P14784	IL2RB	P28482	MAPK1	S538	Q543H	543	Missense	distal	5	no	8.211	8.204	EPSD	COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P14784	IL2RB	P28482	MAPK1	S538	S538F	538	Missense	central	0	yes	8.211	0.000	EPSD	COSMIC	8.102	Loss
CMGC_MAPK_ERK1_MAPK1_ST	P49841	GSK3B	P28482	MAPK1	T7	S9F	9	Missense	proximal	2	no	8.162	8.030	EPSD	COSMIC	8.102	Loss
CMGC_MAPK_ERK1_MAPK1_ST	P49841	GSK3B	P28482	MAPK1	T7	S2P	2	Missense	distal	-5	no	8.162	8.088	EPSD	COSMIC	8.102	Loss
CMGC_MAPK_ERK1_MAPK1_ST	P49841	GSK3B	P28482	MAPK1	T43	G47C	47	Missense	distal	4	no	15.197	14.965	PhosphoSitePlus	COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P49841	GSK3B	P28482	MAPK1	T43	V41G	41	Missense	proximal	-2	no	15.197	13.876	PhosphoSitePlus	COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P49841	GSK3B	P28482	MAPK1	T43	V37G	37	Missense	distal	-6	no	15.197	15.241	PhosphoSitePlus	COSMIC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P49841	GSK3B	P28482	MAPK1	S215	Y222C	222	Missense	distal	7	no	8.103	8.244	EPSD	COSMIC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P49841	GSK3B	P28482	MAPK1	T275	R278M	278	Missense	distal	3	no	14.438	14.477	EPSD	COSMIC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P49841	GSK3B	P28482	MAPK1	T324	R319C	319	Missense	distal	-5	no	14.097	14.327	EPSD	COSMIC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P49841	GSK3B	P28482	MAPK1	T324	R319Q	319	Missense	distal	-5	no	14.097	14.175	EPSD	COSMIC;GDSC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P49841	GSK3B	P28482	MAPK1	T390	Q385P	385	Missense	distal	-5	no	10.997	10.873	EPSD	COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P49841	GSK3B	P28482	MAPK1	T390	P391L	391	Missense	proximal	1	no	10.997	2.188	EPSD	COSMIC	8.102	Loss
CMGC_MAPK_ERK1_MAPK1_ST	P49841	GSK3B	P28482	MAPK1	T390	A397V	397	Missense	distal	7	no	10.997	11.099	EPSD	COSMIC;CCLE	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P06239	LCK	P28482	MAPK1	S59	P57L	57	Missense	proximal	-2	no	17.671	15.754	PhosphoSitePlus	COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P06239	LCK	P28482	MAPK1	S156	F151S	151	Missense	distal	-5	no	8.235	8.147	EPSD	COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P06239	LCK	P28482	MAPK1	S156	G161R	161	Missense	distal	5	no	8.235	8.286	EPSD	COSMIC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P06239	LCK	P28482	MAPK1	S156	A160V	160	Missense	distal	4	no	8.235	8.229	EPSD	COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P06239	LCK	P28482	MAPK1	S162	A160V	160	Missense	proximal	-2	no	7.940	9.214	EPSD	COSMIC	8.102	Gain
CMGC_MAPK_ERK1_MAPK1_ST	P06239	LCK	P28482	MAPK1	S194	P200L	200	Missense	distal	6	no	15.100	14.694	EPSD	COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P06239	LCK	P28482	MAPK1	S194	D187N	187	Missense	distal	-7	no	15.100	15.101	EPSD	COSMIC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P06239	LCK	P28482	MAPK1	S194	I197F	197	Missense	distal	3	no	15.100	15.104	EPSD	COSMIC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P06239	LCK	P28482	MAPK1	T198	P200L	200	Missense	proximal	2	no	9.968	9.820	EPSD	COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P06239	LCK	P28482	MAPK1	T198	I197F	197	Missense	proximal	-1	no	9.968	9.944	EPSD	COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P06239	LCK	P28482	MAPK1	S281	P282L	282	Missense	proximal	1	no	14.176	5.367	EPSD	COSMIC	8.102	Loss
CMGC_MAPK_ERK1_MAPK1_ST	P06239	LCK	P28482	MAPK1	S281	A287V	287	Missense	distal	6	no	14.176	14.258	EPSD	COSMIC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P06239	LCK	P28482	MAPK1	S281	K276E	276	Missense	distal	-5	no	14.176	14.199	EPSD	COSMIC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P06239	LCK	P28482	MAPK1	T330	P331S	331	Missense	proximal	1	no	15.604	6.209	EPSD	COSMIC	8.102	Loss
CMGC_MAPK_ERK1_MAPK1_ST	P06239	LCK	P28482	MAPK1	S373	S377G	377	Missense	distal	4	no	8.607	8.558	EPSD	COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P06239	LCK	P28482	MAPK1	S373	K379E	379	Missense	distal	6	no	8.607	8.584	EPSD	COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P06239	LCK	P28482	MAPK1	S373	R366W	366	Missense	distal	-7	no	8.607	8.556	EPSD	COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P06239	LCK	P28482	MAPK1	S373	N369S	369	Missense	distal	-4	no	8.607	8.566	EPSD	COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P06239	LCK	P28482	MAPK1	S492	P485H	485	Missense	distal	-7	no	8.103	8.087	EPSD	COSMIC	8.102	Loss
CMGC_MAPK_ERK1_MAPK1_ST	P06239	LCK	P28482	MAPK1	S492	R491W	491	Missense	proximal	-1	no	8.103	8.002	EPSD	COSMIC	8.102	Loss
CMGC_MAPK_ERK1_MAPK1_ST	P42702	LIFR	P28482	MAPK1	S534	H528Y	528	Missense	distal	-6	no	16.663	16.597	EPSD	COSMIC;GDSC;CCLE	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P42702	LIFR	P28482	MAPK1	S534	K537N	537	Missense	distal	3	no	16.663	16.656	EPSD	COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P42702	LIFR	P28482	MAPK1	T541	K537N	537	Missense	distal	-4	no	11.630	11.598	EPSD	COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P42702	LIFR	P28482	MAPK1	T541	S546N	546	Missense	distal	5	no	11.630	11.557	EPSD	COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P42702	LIFR	P28482	MAPK1	S887	V888F	888	Missense	proximal	1	no	5.533	8.504	EPSD	COSMIC	8.102	Gain
CMGC_MAPK_ERK1_MAPK1_ST	P42702	LIFR	P28482	MAPK1	T904	P902L	902	Missense	proximal	-2	no	15.958	14.041	EPSD	COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P42702	LIFR	P28482	MAPK1	T904	T904A	904	Missense	central	0	yes	15.958	0.000	EPSD	COSMIC	8.102	Loss
CMGC_MAPK_ERK1_MAPK1_ST	P42702	LIFR	P28482	MAPK1	S927	E934K	934	Missense	distal	7	no	14.180	14.187	EPSD	COSMIC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P42702	LIFR	P28482	MAPK1	S1041	P1042S	1042	Missense	proximal	1	no	15.138	5.743	EPSD	COSMIC	8.102	Loss
CMGC_MAPK_ERK1_MAPK1_ST	P42702	LIFR	P28482	MAPK1	S1041	R1046I	1046	Missense	distal	5	no	15.138	14.789	EPSD	COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P42702	LIFR	P28482	MAPK1	S1041	P1042L	1042	Missense	proximal	1	no	15.138	6.328	EPSD	COSMIC	8.102	Loss
CMGC_MAPK_ERK1_MAPK1_ST	P42702	LIFR	P28482	MAPK1	S1041	V1040E	1040	Missense	proximal	-1	no	15.138	15.149	EPSD	COSMIC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P42702	LIFR	P28482	MAPK1	S1044	P1042S	1042	Missense	proximal	-2	no	18.089	15.255	PhosphoSitePlus	COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P42702	LIFR	P28482	MAPK1	S1044	R1046I	1046	Missense	proximal	2	no	18.089	17.805	PhosphoSitePlus	COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P42702	LIFR	P28482	MAPK1	S1044	P1042L	1042	Missense	proximal	-2	no	18.089	16.172	PhosphoSitePlus	COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P42702	LIFR	P28482	MAPK1	S1044	V1040E	1040	Missense	distal	-4	no	18.089	18.414	PhosphoSitePlus	COSMIC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P42702	LIFR	P28482	MAPK1	S1044	D1049Y	1049	Missense	distal	5	no	18.089	17.775	PhosphoSitePlus	COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P42702	LIFR	P28482	MAPK1	S1047	P1042S	1042	Missense	distal	-5	no	8.706	8.780	EPSD	COSMIC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P42702	LIFR	P28482	MAPK1	S1047	R1046I	1046	Missense	proximal	-1	no	8.706	8.660	EPSD	COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P42702	LIFR	P28482	MAPK1	S1047	P1042L	1042	Missense	distal	-5	no	8.706	8.855	EPSD	COSMIC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P42702	LIFR	P28482	MAPK1	S1047	V1040E	1040	Missense	distal	-7	no	8.706	8.730	EPSD	COSMIC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P42702	LIFR	P28482	MAPK1	S1047	D1049Y	1049	Missense	proximal	2	no	8.706	8.526	EPSD	COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P42702	LIFR	P28482	MAPK1	S1056	P1060A	1060	Missense	distal	4	no	10.056	9.952	EPSD	COSMIC;GDSC;CCLE	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P42702	LIFR	P28482	MAPK1	S1056	D1049Y	1049	Missense	distal	-7	no	10.056	10.024	EPSD	COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P42702	LIFR	P28482	MAPK1	S1059	P1060A	1060	Missense	proximal	1	no	13.739	6.108	EPSD	COSMIC;GDSC;CCLE	8.102	Loss
CMGC_MAPK_ERK1_MAPK1_ST	P42702	LIFR	P28482	MAPK1	S1062	P1060A	1060	Missense	proximal	-2	no	8.299	5.152	EPSD	COSMIC;GDSC;CCLE	8.102	Loss
CMGC_MAPK_ERK1_MAPK1_ST	P42702	LIFR	P28482	MAPK1	S1062	F1068L	1068	Missense	distal	6	no	8.299	8.333	EPSD	COSMIC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P42702	LIFR	P28482	MAPK1	S1077	G1084E	1084	Missense	distal	7	no	15.325	15.198	EPSD	COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P42702	LIFR	P28482	MAPK1	S1077	P1072H	1072	Missense	distal	-5	no	15.325	15.450	EPSD	COSMIC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P42702	LIFR	P28482	MAPK1	S1086	G1084E	1084	Missense	proximal	-2	no	7.713	8.527	EPSD	COSMIC	8.102	Gain
CMGC_MAPK_ERK1_MAPK1_ST	P42702	LIFR	P28482	MAPK1	T1088	N1089H	1089	Missense	proximal	1	no	-3.115	8.784	EPSD	COSMIC	8.102	Gain
CMGC_MAPK_ERK1_MAPK1_ST	Q14247	CTTN	P28482	MAPK1	S332	T328A	328	Missense	distal	-4	no	8.094	8.114	EPSD	COSMIC	8.102	Gain
CMGC_MAPK_ERK1_MAPK1_ST	Q14247	CTTN	P28482	MAPK1	T401	Q394K	394	Missense	distal	-7	no	11.749	11.745	EPSD	COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q14247	CTTN	P28482	MAPK1	T401	R396T	396	Missense	distal	-5	no	11.749	11.805	EPSD	COSMIC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q14247	CTTN	P28482	MAPK1	S405	T411I	411	Missense	distal	6	no	15.769	15.312	PhosphoSitePlus;EPSD	COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q14247	CTTN	P28482	MAPK1	S418	T411I	411	Missense	distal	-7	no	16.346	16.331	EPSD;PhosphoSitePlus	COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q14247	CTTN	P28482	MAPK1	S418	V420I	420	Missense	proximal	2	no	16.346	16.229	EPSD;PhosphoSitePlus	COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q14247	CTTN	P28482	MAPK1	S426	V420I	420	Missense	distal	-6	no	8.657	8.616	EPSD	COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q14247	CTTN	P28482	MAPK1	S426	S426F	426	Missense	central	0	yes	8.657	0.000	EPSD	COSMIC	8.102	Loss
CMGC_MAPK_ERK1_MAPK1_ST	P62070	RRAS2	P28482	MAPK1	S186	Q179R	179	Missense	distal	-7	no	19.203	19.195	PhosphoSitePlus	COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q00059	TFAM	P28482	MAPK1	S31	F33L	33	Missense	proximal	2	no	11.239	11.251	EPSD	COSMIC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q00059	TFAM	P28482	MAPK1	S31	F35C	35	Missense	distal	4	no	11.239	11.135	EPSD	COSMIC;GDSC;CCLE	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q00059	TFAM	P28482	MAPK1	S34	F33L	33	Missense	proximal	-1	no	9.769	9.799	EPSD	COSMIC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q00059	TFAM	P28482	MAPK1	S34	F35C	35	Missense	proximal	1	no	9.769	2.891	EPSD	COSMIC;GDSC;CCLE	8.102	Loss
CMGC_MAPK_ERK1_MAPK1_ST	Q00059	TFAM	P28482	MAPK1	S56	R59Q	59	Missense	distal	3	no	8.734	8.756	EPSD	COSMIC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q00059	TFAM	P28482	MAPK1	S56	R59L	59	Missense	distal	3	no	8.734	8.777	EPSD	COSMIC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q00059	TFAM	P28482	MAPK1	S56	K62I	62	Missense	distal	6	no	8.734	8.010	EPSD	COSMIC	8.102	Loss
CMGC_MAPK_ERK1_MAPK1_ST	Q00059	TFAM	P28482	MAPK1	S56	V54L	54	Missense	proximal	-2	no	8.734	8.689	EPSD	COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q00059	TFAM	P28482	MAPK1	S160	P158T	158	Missense	proximal	-2	no	8.338	5.639	EPSD	COSMIC	8.102	Loss
CMGC_MAPK_ERK1_MAPK1_ST	Q00059	TFAM	P28482	MAPK1	S160	N163S	163	Missense	distal	3	no	8.338	8.416	EPSD	COSMIC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q00059	TFAM	P28482	MAPK1	S177	A173T	173	Missense	distal	-4	no	12.822	12.802	PhosphoSitePlus	COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q00059	TFAM	P28482	MAPK1	S177	Q171K	171	Missense	distal	-6	no	12.822	12.823	PhosphoSitePlus	COSMIC;GDSC;CCLE	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q05682	CALD1	P28482	MAPK1	S129	L130P	130	Missense	proximal	1	no	4.884	13.694	EPSD	COSMIC	8.102	Gain
CMGC_MAPK_ERK1_MAPK1_ST	Q05682	CALD1	P28482	MAPK1	S153	T147A	147	Missense	distal	-6	no	8.468	8.478	EPSD	COSMIC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q05682	CALD1	P28482	MAPK1	S153	Q157K	157	Missense	distal	4	no	8.468	8.553	EPSD	COSMIC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q05682	CALD1	P28482	MAPK1	S480	R484H	484	Missense	distal	4	no	8.366	8.225	EPSD	COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q05682	CALD1	P28482	MAPK1	S480	M482I	482	Missense	proximal	2	no	8.366	8.386	EPSD	COSMIC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q05682	CALD1	P28482	MAPK1	S480	R484Q	484	Missense	distal	4	no	8.366	8.291	EPSD	COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q05682	CALD1	P28482	MAPK1	S480	R484L	484	Missense	distal	4	no	8.366	8.279	EPSD	COSMIC;GDSC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q05682	CALD1	P28482	MAPK1	S480	R484G	484	Missense	distal	4	no	8.366	8.340	EPSD	COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q05682	CALD1	P28482	MAPK1	S480	E477K	477	Missense	distal	-3	no	8.366	8.288	EPSD	COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q05682	CALD1	P28482	MAPK1	T638	G641S	641	Missense	distal	3	no	12.242	12.228	EPSD	COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q05682	CALD1	P28482	MAPK1	T638	P633S	633	Missense	distal	-5	no	12.242	12.316	EPSD	COSMIC;GDSC;CCLE	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q05682	CALD1	P28482	MAPK1	S724	T726I	726	Missense	proximal	2	no	14.776	14.656	EPSD	COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q05682	CALD1	P28482	MAPK1	T730	T726I	726	Missense	distal	-4	no	14.466	14.108	EPSD	COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q05682	CALD1	P28482	MAPK1	T730	N732H	732	Missense	proximal	2	no	14.466	14.412	EPSD	COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q05682	CALD1	P28482	MAPK1	T730	K733N	733	Missense	distal	3	no	14.466	14.459	EPSD	COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q05682	CALD1	P28482	MAPK1	T730	N732S	732	Missense	proximal	2	no	14.466	14.514	EPSD	COSMIC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q05682	CALD1	P28482	MAPK1	S744	R745H	745	Missense	proximal	1	no	6.342	8.173	EPSD	COSMIC	8.102	Gain
CMGC_MAPK_ERK1_MAPK1_ST	Q05682	CALD1	P28482	MAPK1	S759	S765F	765	Missense	distal	6	no	12.022	11.581	EPSD	COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q05682	CALD1	P28482	MAPK1	S789	D785N	785	Missense	distal	-4	no	16.099	16.071	EPSD	COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P00558	PGK1	P28482	MAPK1	S399	S393I	393	Missense	distal	-6	no	8.780	8.678	EPSD	COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P46527	CDKN1B	P28482	MAPK1	S10	R5L	5	Missense	distal	-5	no	14.720	14.821	PhosphoSitePlus;EPSD	COSMIC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P46527	CDKN1B	P28482	MAPK1	S10	E14K	14	Missense	distal	4	no	14.720	14.734	PhosphoSitePlus;EPSD	COSMIC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P46527	CDKN1B	P28482	MAPK1	S10	M16T	16	Missense	distal	6	no	14.720	14.943	PhosphoSitePlus;EPSD	COSMIC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P46527	CDKN1B	P28482	MAPK1	S10	N3D	3	Missense	distal	-7	no	14.720	14.719	PhosphoSitePlus;EPSD	COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P46527	CDKN1B	P28482	MAPK1	S10	P11S	11	Missense	proximal	1	no	14.720	5.325	PhosphoSitePlus;EPSD	COSMIC	8.102	Loss
CMGC_MAPK_ERK1_MAPK1_ST	P46527	CDKN1B	P28482	MAPK1	S10	S12N	12	Missense	proximal	2	no	14.720	14.672	PhosphoSitePlus;EPSD	COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P46527	CDKN1B	P28482	MAPK1	S10	D17E	17	Missense	distal	7	no	14.720	14.665	PhosphoSitePlus;EPSD	COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P46527	CDKN1B	P28482	MAPK1	S178	V184L	184	Missense	distal	6	no	16.020	15.828	EPSD;PhosphoSitePlus	COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P46527	CDKN1B	P28482	MAPK1	S178	G182D	182	Missense	distal	4	no	16.020	15.972	EPSD;PhosphoSitePlus	COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P46527	CDKN1B	P28482	MAPK1	T187	V184L	184	Missense	distal	-3	no	15.791	15.715	EPSD;PhosphoSitePlus	COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P46527	CDKN1B	P28482	MAPK1	T187	G182D	182	Missense	distal	-5	no	15.791	15.793	EPSD;PhosphoSitePlus	COSMIC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P46527	CDKN1B	P28482	MAPK1	T187	R194K	194	Missense	distal	7	no	15.791	15.736	EPSD;PhosphoSitePlus	COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P11308	ERG	P28482	MAPK1	T32	T32M	32	Missense	central	0	yes	14.088	0.000	EPSD	COSMIC	8.102	Loss
CMGC_MAPK_ERK1_MAPK1_ST	P11308	ERG	P28482	MAPK1	T32	G31R	31	Missense	proximal	-1	no	14.088	14.123	EPSD	COSMIC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P11308	ERG	P28482	MAPK1	T32	E39Q	39	Missense	distal	7	no	14.088	14.266	EPSD	COSMIC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P11308	ERG	P28482	MAPK1	T32	K37N	37	Missense	distal	5	no	14.088	14.119	EPSD	COSMIC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P11308	ERG	P28482	MAPK1	T32	L35M	35	Missense	distal	3	no	14.088	14.083	EPSD	COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P11308	ERG	P28482	MAPK1	T32	L25Q	25	Missense	distal	-7	no	14.088	14.103	EPSD	COSMIC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P11308	ERG	P28482	MAPK1	S55	R57H	57	Missense	proximal	2	no	15.048	14.805	EPSD	COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P11308	ERG	P28482	MAPK1	S55	Q61P	61	Missense	distal	6	no	15.048	15.335	EPSD	COSMIC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P11308	ERG	P28482	MAPK1	S55	S55I	55	Missense	central	0	yes	15.048	0.000	EPSD	COSMIC	8.102	Loss
CMGC_MAPK_ERK1_MAPK1_ST	P11308	ERG	P28482	MAPK1	S55	S52F	52	Missense	distal	-3	no	15.048	14.815	EPSD	COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P11308	ERG	P28482	MAPK1	S55	R57C	57	Missense	proximal	2	no	15.048	14.675	EPSD	COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P11308	ERG	P28482	MAPK1	S65	Q66P	66	Missense	proximal	1	no	6.081	14.574	EPSD	COSMIC	8.102	Gain
CMGC_MAPK_ERK1_MAPK1_ST	P11308	ERG	P28482	MAPK1	S88	P89S	89	Missense	proximal	1	no	15.332	5.937	EPSD	COSMIC	8.102	Loss
CMGC_MAPK_ERK1_MAPK1_ST	P11308	ERG	P28482	MAPK1	S88	G84D	84	Missense	distal	-4	no	15.332	15.667	EPSD	COSMIC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P11308	ERG	P28482	MAPK1	S88	V82M	82	Missense	distal	-6	no	15.332	15.334	EPSD	COSMIC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P11308	ERG	P28482	MAPK1	S103	N110S	110	Missense	distal	7	no	16.533	16.551	PhosphoSitePlus;EPSD	COSMIC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P11308	ERG	P28482	MAPK1	S103	M109L	109	Missense	distal	6	no	16.533	16.560	PhosphoSitePlus;EPSD	COSMIC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P11308	ERG	P28482	MAPK1	S103	K96R	96	Missense	distal	-7	no	16.533	16.530	PhosphoSitePlus;EPSD	COSMIC;GDSC;CCLE	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P11308	ERG	P28482	MAPK1	S103	M109I	109	Missense	distal	6	no	16.533	16.300	PhosphoSitePlus;EPSD	COSMIC;CCLE	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P11308	ERG	P28482	MAPK1	S103	G108W	108	Missense	distal	5	no	16.533	16.056	PhosphoSitePlus;EPSD	COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P11308	ERG	P28482	MAPK1	S222	P223S	223	Missense	proximal	1	no	13.432	4.038	EPSD;PhosphoSitePlus	COSMIC	8.102	Loss
CMGC_MAPK_ERK1_MAPK1_ST	P11308	ERG	P28482	MAPK1	S222	H227N	227	Missense	distal	5	no	13.432	13.505	EPSD;PhosphoSitePlus	COSMIC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P11308	ERG	P28482	MAPK1	S222	R224Q	224	Missense	proximal	2	no	13.432	13.141	EPSD;PhosphoSitePlus	COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P11308	ERG	P28482	MAPK1	S222	M226I	226	Missense	distal	4	no	13.432	13.454	EPSD;PhosphoSitePlus	COSMIC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P11308	ERG	P28482	MAPK1	S283	P288L	288	Missense	distal	5	no	12.681	12.468	EPSD	COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P11308	ERG	P28482	MAPK1	S283	P288S	288	Missense	distal	5	no	12.681	12.699	EPSD	COSMIC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P11308	ERG	P28482	MAPK1	S283	Q281H	281	Missense	proximal	-2	no	12.681	12.920	EPSD	COSMIC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P11308	ERG	P28482	MAPK1	S283	A280T	280	Missense	distal	-3	no	12.681	12.839	EPSD	COSMIC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P11308	ERG	P28482	MAPK1	S283	S277N	277	Missense	distal	-6	no	12.681	12.685	EPSD	COSMIC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P11308	ERG	P28482	MAPK1	S283	S277I	277	Missense	distal	-6	no	12.681	12.580	EPSD	COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P11308	ERG	P28482	MAPK1	S283	P282S	282	Missense	proximal	-1	no	12.681	12.638	EPSD	COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P11308	ERG	P28482	MAPK1	S283	S283N	283	Missense	central	0	yes	12.681	0.000	EPSD	COSMIC	8.102	Loss
CMGC_MAPK_ERK1_MAPK1_ST	P11308	ERG	P28482	MAPK1	S283	Q281E	281	Missense	proximal	-2	no	12.681	13.295	EPSD	COSMIC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P11308	ERG	P28482	MAPK1	S283	P288H	288	Missense	distal	5	no	12.681	12.554	EPSD	COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P11308	ERG	P28482	MAPK1	S283	S283I	283	Missense	central	0	yes	12.681	0.000	EPSD	COSMIC	8.102	Loss
CMGC_MAPK_ERK1_MAPK1_ST	P11308	ERG	P28482	MAPK1	S283	S277L	277	Missense	distal	-6	no	12.681	12.616	EPSD	COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P11308	ERG	P28482	MAPK1	S283	P282L	282	Missense	proximal	-1	no	12.681	12.622	EPSD	COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P22736	NR4A1	P28482	MAPK1	T10	A6T	6	Missense	distal	-4	no	14.133	14.113	EPSD	COSMIC;GDSC;CCLE	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P22736	NR4A1	P28482	MAPK1	T10	P13L	13	Missense	distal	3	no	14.133	14.223	EPSD	COSMIC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P22736	NR4A1	P28482	MAPK1	T10	G9W	9	Missense	proximal	-1	no	14.133	14.067	EPSD	COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P22736	NR4A1	P28482	MAPK1	S14	P13L	13	Missense	proximal	-1	no	15.054	14.994	EPSD	COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P22736	NR4A1	P28482	MAPK1	S14	R18C	18	Missense	distal	4	no	15.054	14.795	EPSD	COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P22736	NR4A1	P28482	MAPK1	S14	G9W	9	Missense	distal	-5	no	15.054	15.310	EPSD	COSMIC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P22736	NR4A1	P28482	MAPK1	S23	R18C	18	Missense	distal	-5	no	8.780	9.010	EPSD	COSMIC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P22736	NR4A1	P28482	MAPK1	S95	T88A	88	Missense	distal	-7	no	12.717	12.732	EPSD	COSMIC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P22736	NR4A1	P28482	MAPK1	S95	S98P	98	Missense	distal	3	no	12.717	12.648	EPSD	COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P22736	NR4A1	P28482	MAPK1	S100	S98P	98	Missense	proximal	-2	no	7.658	10.492	EPSD	COSMIC	8.102	Gain
CMGC_MAPK_ERK1_MAPK1_ST	P22736	NR4A1	P28482	MAPK1	S140	S137L	137	Missense	distal	-3	no	13.969	13.762	EPSD	COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P22736	NR4A1	P28482	MAPK1	S140	P135S	135	Missense	distal	-5	no	13.969	14.043	EPSD	COSMIC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P22736	NR4A1	P28482	MAPK1	S140	F146C	146	Missense	distal	6	no	13.969	13.542	EPSD	COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P22736	NR4A1	P28482	MAPK1	S140	P139L	139	Missense	proximal	-1	no	13.969	13.909	EPSD	COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P22736	NR4A1	P28482	MAPK1	S140	S142F	142	Missense	proximal	2	no	13.969	13.837	EPSD	COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P22736	NR4A1	P28482	MAPK1	T143	P148S	148	Missense	distal	5	no	18.045	18.063	EPSD	COSMIC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P22736	NR4A1	P28482	MAPK1	T143	S137L	137	Missense	distal	-6	no	18.045	17.979	EPSD	COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P22736	NR4A1	P28482	MAPK1	T143	F146C	146	Missense	distal	3	no	18.045	18.086	EPSD	COSMIC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P22736	NR4A1	P28482	MAPK1	T143	P139L	139	Missense	distal	-4	no	18.045	17.741	EPSD	COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P22736	NR4A1	P28482	MAPK1	T143	S142F	142	Missense	proximal	-1	no	18.045	17.999	EPSD	COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P22736	NR4A1	P28482	MAPK1	S152	P148S	148	Missense	distal	-4	no	14.120	14.036	EPSD	COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P22736	NR4A1	P28482	MAPK1	S152	S152P	152	Missense	central	0	yes	14.120	0.000	EPSD	COSMIC	8.102	Loss
CMGC_MAPK_ERK1_MAPK1_ST	P22736	NR4A1	P28482	MAPK1	S152	F146C	146	Missense	distal	-6	no	14.120	14.064	EPSD	COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P22736	NR4A1	P28482	MAPK1	S152	S157F	157	Missense	distal	5	no	14.120	13.923	EPSD	COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P22736	NR4A1	P28482	MAPK1	S152	G159S	159	Missense	distal	7	no	14.120	14.051	EPSD	COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P22736	NR4A1	P28482	MAPK1	S191	S191L	191	Missense	central	0	yes	8.482	0.000	EPSD	COSMIC	8.102	Loss
CMGC_MAPK_ERK1_MAPK1_ST	P22736	NR4A1	P28482	MAPK1	S191	S191W	191	Missense	central	0	yes	8.482	0.000	EPSD	COSMIC	8.102	Loss
CMGC_MAPK_ERK1_MAPK1_ST	P22736	NR4A1	P28482	MAPK1	S191	S191F	191	Missense	central	0	yes	8.482	0.000	EPSD	COSMIC	8.102	Loss
CMGC_MAPK_ERK1_MAPK1_ST	P22736	NR4A1	P28482	MAPK1	S191	P187S	187	Missense	distal	-4	no	8.482	8.399	EPSD	COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P22736	NR4A1	P28482	MAPK1	S191	P198R	198	Missense	distal	7	no	8.482	8.497	EPSD	COSMIC;GDSC;CCLE	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P22736	NR4A1	P28482	MAPK1	S193	P200S	200	Missense	distal	7	no	11.551	11.561	EPSD	COSMIC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P22736	NR4A1	P28482	MAPK1	S193	S191L	191	Missense	proximal	-2	no	11.551	12.467	EPSD	COSMIC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P22736	NR4A1	P28482	MAPK1	S193	S191W	191	Missense	proximal	-2	no	11.551	11.643	EPSD	COSMIC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P22736	NR4A1	P28482	MAPK1	S193	S191F	191	Missense	proximal	-2	no	11.551	11.744	EPSD	COSMIC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P22736	NR4A1	P28482	MAPK1	S193	P187S	187	Missense	distal	-6	no	11.551	11.524	EPSD	COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P22736	NR4A1	P28482	MAPK1	S193	P200L	200	Missense	distal	7	no	11.551	11.850	EPSD	COSMIC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P22736	NR4A1	P28482	MAPK1	S193	P198R	198	Missense	distal	5	no	11.551	11.600	EPSD	COSMIC;GDSC;CCLE	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P22736	NR4A1	P28482	MAPK1	S199	P200S	200	Missense	proximal	1	no	14.359	4.964	EPSD	COSMIC	8.102	Loss
CMGC_MAPK_ERK1_MAPK1_ST	P22736	NR4A1	P28482	MAPK1	S199	S201R	201	Missense	proximal	2	no	14.359	14.500	EPSD	COSMIC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P22736	NR4A1	P28482	MAPK1	S199	P200L	200	Missense	proximal	1	no	14.359	5.549	EPSD	COSMIC	8.102	Loss
CMGC_MAPK_ERK1_MAPK1_ST	P22736	NR4A1	P28482	MAPK1	S199	P198R	198	Missense	proximal	-1	no	14.359	14.340	EPSD	COSMIC;GDSC;CCLE	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P22736	NR4A1	P28482	MAPK1	S205	P211R	211	Missense	distal	6	no	14.005	13.898	EPSD	COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P22736	NR4A1	P28482	MAPK1	S205	P200S	200	Missense	distal	-5	no	14.005	14.079	EPSD	COSMIC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P22736	NR4A1	P28482	MAPK1	S205	S201R	201	Missense	distal	-4	no	14.005	13.999	EPSD	COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P22736	NR4A1	P28482	MAPK1	S205	P200L	200	Missense	distal	-5	no	14.005	14.154	EPSD	COSMIC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P22736	NR4A1	P28482	MAPK1	S205	P198R	198	Missense	distal	-7	no	14.005	14.000	EPSD	COSMIC;GDSC;CCLE	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P22736	NR4A1	P28482	MAPK1	S237	P235L	235	Missense	proximal	-2	no	18.051	16.134	EPSD	COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P22736	NR4A1	P28482	MAPK1	S237	E241G	241	Missense	distal	4	no	18.051	18.029	EPSD	COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P22736	NR4A1	P28482	MAPK1	S360	P361S	361	Missense	proximal	1	no	13.556	4.161	EPSD	COSMIC	8.102	Loss
CMGC_MAPK_ERK1_MAPK1_ST	P22736	NR4A1	P28482	MAPK1	S360	P353L	353	Missense	distal	-7	no	13.556	13.543	EPSD	COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P22736	NR4A1	P28482	MAPK1	S360	P357L	357	Missense	distal	-3	no	13.556	13.172	EPSD	COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P22736	NR4A1	P28482	MAPK1	S360	A359S	359	Missense	proximal	-1	no	13.556	13.549	EPSD	COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P22736	NR4A1	P28482	MAPK1	S360	L364I	364	Missense	distal	4	no	13.556	13.499	EPSD	COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P22736	NR4A1	P28482	MAPK1	S360	A362V	362	Missense	proximal	2	no	13.556	13.632	EPSD	COSMIC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P22736	NR4A1	P28482	MAPK1	S360	A359D	359	Missense	proximal	-1	no	13.556	13.537	EPSD	COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P22736	NR4A1	P28482	MAPK1	S431	P432L	432	Missense	proximal	1	no	13.905	5.096	PhosphoSitePlus	COSMIC	8.102	Loss
CMGC_MAPK_ERK1_MAPK1_ST	P22736	NR4A1	P28482	MAPK1	S431	A433T	433	Missense	proximal	2	no	13.905	13.985	PhosphoSitePlus	COSMIC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P27708	CAD	P28482	MAPK1	T475	R468C	468	Missense	distal	-7	no	8.391	8.359	EPSD	COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P27708	CAD	P28482	MAPK1	T475	T480I	480	Missense	distal	5	no	8.391	8.148	EPSD	COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P27708	CAD	P28482	MAPK1	T475	G478S	478	Missense	distal	3	no	8.391	8.376	EPSD	COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P27708	CAD	P28482	MAPK1	T504	R500L	500	Missense	distal	-4	no	14.739	14.524	EPSD	COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P27708	CAD	P28482	MAPK1	T504	E507D	507	Missense	distal	3	no	14.739	14.835	EPSD	COSMIC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P27708	CAD	P28482	MAPK1	S690	S691P	691	Missense	proximal	1	no	4.808	14.203	EPSD	COSMIC	8.102	Gain
CMGC_MAPK_ERK1_MAPK1_ST	P27708	CAD	P28482	MAPK1	S980	T981P	981	Missense	proximal	1	no	5.260	13.759	EPSD	COSMIC	8.102	Gain
CMGC_MAPK_ERK1_MAPK1_ST	P27708	CAD	P28482	MAPK1	S1038	P1039L	1039	Missense	proximal	1	no	13.738	4.928	EPSD	COSMIC	8.102	Loss
CMGC_MAPK_ERK1_MAPK1_ST	P27708	CAD	P28482	MAPK1	S1038	S1038F	1038	Missense	central	0	yes	13.738	0.000	EPSD	COSMIC	8.102	Loss
CMGC_MAPK_ERK1_MAPK1_ST	P27708	CAD	P28482	MAPK1	S1038	C1032G	1032	Missense	distal	-6	no	13.738	13.862	EPSD	COSMIC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P27708	CAD	P28482	MAPK1	S1038	S1044L	1044	Missense	distal	6	no	13.738	13.331	EPSD	COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P27708	CAD	P28482	MAPK1	S1113	E1108Q	1108	Missense	distal	-5	no	9.752	9.852	EPSD	COSMIC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P27708	CAD	P28482	MAPK1	S1113	S1112C	1112	Missense	proximal	-1	no	9.752	9.674	EPSD	COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P27708	CAD	P28482	MAPK1	S1823	P1818R	1818	Missense	distal	-5	no	11.174	11.221	EPSD	COSMIC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P27708	CAD	P28482	MAPK1	S1823	A1816V	1816	Missense	distal	-7	no	11.174	11.157	EPSD	COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P27708	CAD	P28482	MAPK1	T1833	R1839H	1839	Missense	distal	6	no	15.625	15.427	EPSD	COSMIC;GDSC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P27708	CAD	P28482	MAPK1	T1906	G1908C	1908	Missense	proximal	2	no	13.897	13.619	EPSD	COSMIC;GDSC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P27708	CAD	P28482	MAPK1	S1915	H1919Y	1919	Missense	distal	4	no	13.231	13.200	EPSD	COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P27708	CAD	P28482	MAPK1	S1915	G1908C	1908	Missense	distal	-7	no	13.231	13.212	EPSD	COSMIC;GDSC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q00613	HSF1	P28482	MAPK1	S241	G236S	236	Missense	distal	-5	no	8.721	8.727	EPSD	COSMIC;CCLE	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q00613	HSF1	P28482	MAPK1	S241	S237L	237	Missense	distal	-4	no	8.721	8.500	EPSD	COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q00613	HSF1	P28482	MAPK1	S241	P239H	239	Missense	proximal	-2	no	8.721	5.966	EPSD	COSMIC	8.102	Loss
CMGC_MAPK_ERK1_MAPK1_ST	Q00613	HSF1	P28482	MAPK1	S241	S244F	244	Missense	distal	3	no	8.721	8.783	EPSD	COSMIC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q00613	HSF1	P28482	MAPK1	S244	S237L	237	Missense	distal	-7	no	13.950	13.942	EPSD	COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q00613	HSF1	P28482	MAPK1	S244	P239H	239	Missense	distal	-5	no	13.950	14.075	EPSD	COSMIC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q00613	HSF1	P28482	MAPK1	S244	S244F	244	Missense	central	0	yes	13.950	0.000	EPSD	COSMIC	8.102	Loss
CMGC_MAPK_ERK1_MAPK1_ST	Q00613	HSF1	P28482	MAPK1	S275	S279F	279	Missense	distal	4	no	17.140	16.962	EPSD	COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q00613	HSF1	P28482	MAPK1	S275	P280L	280	Missense	distal	5	no	17.140	16.926	EPSD	COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q00613	HSF1	P28482	MAPK1	S275	I268V	268	Missense	distal	-7	no	17.140	17.153	EPSD	COSMIC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q00613	HSF1	P28482	MAPK1	S275	G281S	281	Missense	distal	6	no	17.140	17.217	EPSD	COSMIC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q00613	HSF1	P28482	MAPK1	S279	S279F	279	Missense	central	0	yes	12.370	0.000	EPSD	COSMIC	8.102	Loss
CMGC_MAPK_ERK1_MAPK1_ST	Q00613	HSF1	P28482	MAPK1	S279	P280L	280	Missense	proximal	1	no	12.370	3.561	EPSD	COSMIC	8.102	Loss
CMGC_MAPK_ERK1_MAPK1_ST	Q00613	HSF1	P28482	MAPK1	S279	G281S	281	Missense	proximal	2	no	12.370	12.324	EPSD	COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q00613	HSF1	P28482	MAPK1	S279	S283N	283	Missense	distal	4	no	12.370	12.333	EPSD	COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q00613	HSF1	P28482	MAPK1	S290	R287K	287	Missense	distal	-3	no	8.815	8.577	EPSD	COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q00613	HSF1	P28482	MAPK1	S290	S283N	283	Missense	distal	-7	no	8.815	8.817	EPSD	COSMIC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q00613	HSF1	P28482	MAPK1	S292	R287K	287	Missense	distal	-5	no	14.238	14.193	EPSD	COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q00613	HSF1	P28482	MAPK1	S303	S303G	303	Missense	central	0	yes	17.219	0.000	EPSD	COSMIC	8.102	Loss
CMGC_MAPK_ERK1_MAPK1_ST	Q00613	HSF1	P28482	MAPK1	S303	P304L	304	Missense	proximal	1	no	17.219	8.410	EPSD	COSMIC;GDSC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q00613	HSF1	P28482	MAPK1	S303	R309G	309	Missense	distal	6	no	17.219	17.249	EPSD	COSMIC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q00613	HSF1	P28482	MAPK1	S307	S303G	303	Missense	distal	-4	no	15.590	15.324	EPSD	COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q00613	HSF1	P28482	MAPK1	S307	P304L	304	Missense	distal	-3	no	15.590	15.206	EPSD	COSMIC;GDSC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q00613	HSF1	P28482	MAPK1	S307	R309G	309	Missense	proximal	2	no	15.590	15.495	EPSD	COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q00613	HSF1	P28482	MAPK1	S314	R309G	309	Missense	distal	-5	no	14.840	14.860	EPSD	COSMIC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q00613	HSF1	P28482	MAPK1	S314	P318T	318	Missense	distal	4	no	14.840	14.716	EPSD	COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q00613	HSF1	P28482	MAPK1	S326	L330V	330	Missense	distal	4	no	15.123	15.134	PhosphoSitePlus	COSMIC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q00613	HSF1	P28482	MAPK1	S326	P327Q	327	Missense	proximal	1	no	15.123	6.630	PhosphoSitePlus	COSMIC	8.102	Loss
CMGC_MAPK_ERK1_MAPK1_ST	Q00613	HSF1	P28482	MAPK1	S363	S363P	363	Missense	central	0	yes	16.964	0.000	EPSD	COSMIC	8.102	Loss
CMGC_MAPK_ERK1_MAPK1_ST	Q00613	HSF1	P28482	MAPK1	S363	P365Q	365	Missense	proximal	2	no	16.964	16.786	EPSD	COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q00613	HSF1	P28482	MAPK1	S363	D356N	356	Missense	distal	-7	no	16.964	16.965	EPSD	COSMIC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q00613	HSF1	P28482	MAPK1	S363	P365T	365	Missense	proximal	2	no	16.964	16.913	EPSD	COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q00613	HSF1	P28482	MAPK1	S363	E358K	358	Missense	distal	-5	no	16.964	16.941	EPSD	COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q00613	HSF1	P28482	MAPK1	S363	P365L	365	Missense	proximal	2	no	16.964	16.816	EPSD	COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q00613	HSF1	P28482	MAPK1	S368	S363P	363	Missense	distal	-5	no	8.326	8.252	EPSD	COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q00613	HSF1	P28482	MAPK1	S368	P365Q	365	Missense	distal	-3	no	8.326	8.029	EPSD	COSMIC	8.102	Loss
CMGC_MAPK_ERK1_MAPK1_ST	Q00613	HSF1	P28482	MAPK1	S368	P365T	365	Missense	distal	-3	no	8.326	8.117	EPSD	COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q00613	HSF1	P28482	MAPK1	S368	L374F	374	Missense	distal	6	no	8.326	8.292	EPSD	COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q00613	HSF1	P28482	MAPK1	S368	P365L	365	Missense	distal	-3	no	8.326	7.942	EPSD	COSMIC	8.102	Loss
CMGC_MAPK_ERK1_MAPK1_ST	Q00613	HSF1	P28482	MAPK1	T369	S363P	363	Missense	distal	-6	no	12.803	12.830	EPSD	COSMIC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q00613	HSF1	P28482	MAPK1	T369	P365Q	365	Missense	distal	-4	no	12.803	12.611	EPSD	COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q00613	HSF1	P28482	MAPK1	T369	P365T	365	Missense	distal	-4	no	12.803	12.490	EPSD	COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q00613	HSF1	P28482	MAPK1	T369	L374F	374	Missense	distal	5	no	12.803	12.837	EPSD	COSMIC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q00613	HSF1	P28482	MAPK1	T369	P365L	365	Missense	distal	-4	no	12.803	12.499	EPSD	COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q00613	HSF1	P28482	MAPK1	S419	L417Q	417	Missense	proximal	-2	no	14.430	13.354	EPSD	COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q00613	HSF1	P28482	MAPK1	S419	V422M	422	Missense	distal	3	no	14.430	14.458	EPSD	COSMIC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q00613	HSF1	P28482	MAPK1	S419	S419N	419	Missense	central	0	yes	14.430	0.000	EPSD	COSMIC	8.102	Loss
CMGC_MAPK_ERK1_MAPK1_ST	Q00613	HSF1	P28482	MAPK1	S444	E447K	447	Missense	distal	3	no	16.077	16.084	EPSD	COSMIC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q00613	HSF1	P28482	MAPK1	S458	P452H	452	Missense	distal	-6	no	15.044	14.969	EPSD	COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q00613	HSF1	P28482	MAPK1	S513	E519K	519	Missense	distal	6	no	8.309	8.332	EPSD	COSMIC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q969H0	FBXW7	P28482	MAPK1	T205	F209C	209	Missense	distal	4	no	12.937	12.833	PhosphoSitePlus	COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q969H0	FBXW7	P28482	MAPK1	T205	D211N	211	Missense	distal	6	no	12.937	12.886	PhosphoSitePlus	COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q969H0	FBXW7	P28482	MAPK1	T205	S203L	203	Missense	proximal	-2	no	12.937	13.854	PhosphoSitePlus	COSMIC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q969H0	FBXW7	P28482	MAPK1	T205	L199F	199	Missense	distal	-6	no	12.937	12.919	PhosphoSitePlus	COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q969H0	FBXW7	P28482	MAPK1	T205	V200I	200	Missense	distal	-5	no	12.937	13.050	PhosphoSitePlus	COSMIC;GDSC;CCLE	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q969H0	FBXW7	P28482	MAPK1	T205	D211Y	211	Missense	distal	6	no	12.937	12.364	PhosphoSitePlus	COSMIC;GDSC;CCLE	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q969H0	FBXW7	P28482	MAPK1	S349	G345D	345	Missense	distal	-4	no	14.977	15.313	EPSD	COSMIC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q969H0	FBXW7	P28482	MAPK1	S349	A354S	354	Missense	distal	5	no	14.977	15.137	EPSD	COSMIC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q969H0	FBXW7	P28482	MAPK1	S372	H379Y	379	Missense	distal	7	no	14.301	14.596	EPSD	COSMIC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q969H0	FBXW7	P28482	MAPK1	S372	H379P	379	Missense	distal	7	no	14.301	14.068	EPSD	COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q969H0	FBXW7	P28482	MAPK1	S372	R367P	367	Missense	distal	-5	no	14.301	14.254	EPSD	COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q969H0	FBXW7	P28482	MAPK1	S372	V375M	375	Missense	distal	3	no	14.301	14.329	EPSD	COSMIC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q969H0	FBXW7	P28482	MAPK1	S372	H379R	379	Missense	distal	7	no	14.301	14.082	EPSD	COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q969H0	FBXW7	P28482	MAPK1	S372	K371T	371	Missense	proximal	-1	no	14.301	14.246	EPSD	COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q969H0	FBXW7	P28482	MAPK1	S372	G378E	378	Missense	distal	6	no	14.301	14.412	EPSD	COSMIC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q969H0	FBXW7	P28482	MAPK1	S372	P373L	373	Missense	proximal	1	no	14.301	5.492	EPSD	COSMIC	8.102	Loss
CMGC_MAPK_ERK1_MAPK1_ST	Q969H0	FBXW7	P28482	MAPK1	S372	E369G	369	Missense	distal	-3	no	14.301	14.292	EPSD	COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q969H0	FBXW7	P28482	MAPK1	S372	R366S	366	Missense	distal	-6	no	14.301	14.267	EPSD	COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q969H0	FBXW7	P28482	MAPK1	S372	R366T	366	Missense	distal	-6	no	14.301	14.243	EPSD	COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q969H0	FBXW7	P28482	MAPK1	S372	L376S	376	Missense	distal	4	no	14.301	14.411	EPSD	COSMIC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q969H0	FBXW7	P28482	MAPK1	S372	R366M	366	Missense	distal	-6	no	14.301	14.209	EPSD	COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q969H0	FBXW7	P28482	MAPK1	S688	A685E	685	Missense	distal	-3	no	8.071	8.258	EPSD	COSMIC	8.102	Gain
CMGC_MAPK_ERK1_MAPK1_ST	Q969H0	FBXW7	P28482	MAPK1	S688	A685V	685	Missense	distal	-3	no	8.071	8.131	EPSD	COSMIC	8.102	Gain
CMGC_MAPK_ERK1_MAPK1_ST	Q969H0	FBXW7	P28482	MAPK1	S688	T692S	692	Missense	distal	4	no	8.071	8.184	EPSD	COSMIC	8.102	Gain
CMGC_MAPK_ERK1_MAPK1_ST	Q969H0	FBXW7	P28482	MAPK1	S688	V683M	683	Missense	distal	-5	no	8.071	8.128	EPSD	COSMIC	8.102	Gain
CMGC_MAPK_ERK1_MAPK1_ST	Q969H0	FBXW7	P28482	MAPK1	S688	R689E	689	Missense	proximal	1	no	8.071	8.954	EPSD	COSMIC	8.102	Gain
CMGC_MAPK_ERK1_MAPK1_ST	Q15750	TAB1	P28482	MAPK1	T376	M372I	372	Missense	distal	-4	no	11.228	11.023	EPSD	COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q15750	TAB1	P28482	MAPK1	T376	S373G	373	Missense	distal	-3	no	11.228	11.216	EPSD	COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q15750	TAB1	P28482	MAPK1	T376	E371K	371	Missense	distal	-5	no	11.228	11.206	EPSD	COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q15750	TAB1	P28482	MAPK1	S378	M372I	372	Missense	distal	-6	no	13.001	12.957	EPSD	COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q15750	TAB1	P28482	MAPK1	S378	S373G	373	Missense	distal	-5	no	13.001	12.994	EPSD	COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q15750	TAB1	P28482	MAPK1	S378	E371K	371	Missense	distal	-7	no	13.001	12.994	EPSD	COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q15750	TAB1	P28482	MAPK1	T431	T435I	435	Missense	distal	4	no	12.012	11.959	EPSD	COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q15750	TAB1	P28482	MAPK1	T431	Q437K	437	Missense	distal	6	no	12.012	12.357	EPSD	COSMIC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q15750	TAB1	P28482	MAPK1	S438	P439L	439	Missense	proximal	1	no	13.407	4.598	PhosphoSitePlus	COSMIC	8.102	Loss
CMGC_MAPK_ERK1_MAPK1_ST	Q15750	TAB1	P28482	MAPK1	S438	T435I	435	Missense	distal	-3	no	13.407	13.175	PhosphoSitePlus	COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q15750	TAB1	P28482	MAPK1	S438	Q437K	437	Missense	proximal	-1	no	13.407	13.461	PhosphoSitePlus	COSMIC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q15750	TAB1	P28482	MAPK1	S492	R489C	489	Missense	distal	-3	no	8.195	7.511	EPSD	COSMIC	8.102	Loss
CMGC_MAPK_ERK1_MAPK1_ST	Q15750	TAB1	P28482	MAPK1	S492	Y488C	488	Missense	distal	-4	no	8.195	8.140	EPSD	COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q9Y6K1	DNMT3A	P28482	MAPK1	S15	R19W	19	Missense	distal	4	no	8.539	8.256	EPSD	COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q9Y6K1	DNMT3A	P28482	MAPK1	S15	D11A	11	Missense	distal	-4	no	8.539	8.261	EPSD	COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q9Y6K1	DNMT3A	P28482	MAPK1	S15	E20K	20	Missense	distal	5	no	8.539	8.480	EPSD	COSMIC;CCLE	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q9Y6K1	DNMT3A	P28482	MAPK1	S15	D22G	22	Missense	distal	7	no	8.539	8.612	EPSD	COSMIC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q9Y6K1	DNMT3A	P28482	MAPK1	S15	E18K	18	Missense	distal	3	no	8.539	8.546	EPSD	COSMIC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q9Y6K1	DNMT3A	P28482	MAPK1	T65	P59S	59	Missense	distal	-6	no	13.845	13.819	EPSD	COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q9Y6K1	DNMT3A	P28482	MAPK1	T65	D64A	64	Missense	proximal	-1	no	13.845	13.864	EPSD	COSMIC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q9Y6K1	DNMT3A	P28482	MAPK1	T65	P58L	58	Missense	distal	-7	no	13.845	13.833	EPSD	COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q9Y6K1	DNMT3A	P28482	MAPK1	T65	P59L	59	Missense	distal	-6	no	13.845	13.753	EPSD	COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q9Y6K1	DNMT3A	P28482	MAPK1	T65	P59Q	59	Missense	distal	-6	no	13.845	13.830	EPSD	COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q9Y6K1	DNMT3A	P28482	MAPK1	T65	A70G	70	Missense	distal	5	no	13.845	13.986	EPSD	COSMIC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q9Y6K1	DNMT3A	P28482	MAPK1	S75	S75Y	75	Missense	central	0	yes	11.951	0.000	EPSD	COSMIC	8.102	Loss
CMGC_MAPK_ERK1_MAPK1_ST	Q9Y6K1	DNMT3A	P28482	MAPK1	S75	M78I	78	Missense	distal	3	no	11.951	11.993	EPSD	COSMIC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q9Y6K1	DNMT3A	P28482	MAPK1	S75	A70G	70	Missense	distal	-5	no	11.951	11.894	EPSD	COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q9Y6K1	DNMT3A	P28482	MAPK1	S105	A107V	107	Missense	proximal	2	no	14.989	15.065	EPSD	COSMIC;GDSC;CCLE	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q9Y6K1	DNMT3A	P28482	MAPK1	S105	P99S	99	Missense	distal	-6	no	14.989	14.963	EPSD	COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q9Y6K1	DNMT3A	P28482	MAPK1	S105	P106R	106	Missense	proximal	1	no	14.989	5.334	EPSD	COSMIC	8.102	Loss
CMGC_MAPK_ERK1_MAPK1_ST	Q9Y6K1	DNMT3A	P28482	MAPK1	S105	G109V	109	Missense	distal	4	no	14.989	14.939	EPSD	COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q9Y6K1	DNMT3A	P28482	MAPK1	S105	G109R	109	Missense	distal	4	no	14.989	15.015	EPSD	COSMIC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q9Y6K1	DNMT3A	P28482	MAPK1	S105	G109E	109	Missense	distal	4	no	14.989	15.011	EPSD	COSMIC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q9Y6K1	DNMT3A	P28482	MAPK1	S105	G104R	104	Missense	proximal	-1	no	14.989	15.024	EPSD	COSMIC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q9Y6K1	DNMT3A	P28482	MAPK1	T138	G142S	142	Missense	distal	4	no	12.941	12.990	EPSD	COSMIC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q9Y6K1	DNMT3A	P28482	MAPK1	T138	R143L	143	Missense	distal	5	no	12.941	12.678	EPSD	COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q9Y6K1	DNMT3A	P28482	MAPK1	T138	A145T	145	Missense	distal	7	no	12.941	12.912	EPSD	COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q9Y6K1	DNMT3A	P28482	MAPK1	T138	R143P	143	Missense	distal	5	no	12.941	12.891	EPSD	COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q9Y6K1	DNMT3A	P28482	MAPK1	T138	R143S	143	Missense	distal	5	no	12.941	12.909	EPSD	COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q9Y6K1	DNMT3A	P28482	MAPK1	S243	E241K	241	Missense	proximal	-2	no	13.554	13.514	EPSD	COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q9Y6K1	DNMT3A	P28482	MAPK1	S243	Q248R	248	Missense	distal	5	no	13.554	13.724	EPSD	COSMIC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q9Y6K1	DNMT3A	P28482	MAPK1	S255	T257N	257	Missense	proximal	2	no	17.002	16.976	PhosphoSitePlus	COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q9Y6K1	DNMT3A	P28482	MAPK1	S255	P262S	262	Missense	distal	7	no	17.002	17.013	PhosphoSitePlus	COSMIC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q9Y6K1	DNMT3A	P28482	MAPK1	S255	A254P	254	Missense	proximal	-1	no	17.002	17.039	PhosphoSitePlus	COSMIC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q9Y6K1	DNMT3A	P28482	MAPK1	S255	T261M	261	Missense	distal	6	no	17.002	16.779	PhosphoSitePlus	COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q9Y6K1	DNMT3A	P28482	MAPK1	S255	A254T	254	Missense	proximal	-1	no	17.002	16.997	PhosphoSitePlus	COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q9Y6K1	DNMT3A	P28482	MAPK1	S255	P256L	256	Missense	proximal	1	no	17.002	8.192	PhosphoSitePlus	COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q9Y6K1	DNMT3A	P28482	MAPK1	S255	P256S	256	Missense	proximal	1	no	17.002	7.607	PhosphoSitePlus	COSMIC	8.102	Loss
CMGC_MAPK_ERK1_MAPK1_ST	Q9Y6K1	DNMT3A	P28482	MAPK1	S255	Q248R	248	Missense	distal	-7	no	17.002	16.994	PhosphoSitePlus	COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q9Y6K1	DNMT3A	P28482	MAPK1	T261	V265L	265	Missense	distal	4	no	13.031	13.020	EPSD	COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q9Y6K1	DNMT3A	P28482	MAPK1	T261	T257N	257	Missense	distal	-4	no	13.031	13.302	EPSD	COSMIC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q9Y6K1	DNMT3A	P28482	MAPK1	T261	P262S	262	Missense	proximal	1	no	13.031	3.636	EPSD	COSMIC	8.102	Loss
CMGC_MAPK_ERK1_MAPK1_ST	Q9Y6K1	DNMT3A	P28482	MAPK1	T261	A254P	254	Missense	distal	-7	no	13.031	13.033	EPSD	COSMIC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q9Y6K1	DNMT3A	P28482	MAPK1	T261	D268H	268	Missense	distal	7	no	13.031	13.257	EPSD	COSMIC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q9Y6K1	DNMT3A	P28482	MAPK1	T261	T261M	261	Missense	central	0	yes	13.031	0.000	EPSD	COSMIC	8.102	Loss
CMGC_MAPK_ERK1_MAPK1_ST	Q9Y6K1	DNMT3A	P28482	MAPK1	T261	A254T	254	Missense	distal	-7	no	13.031	13.016	EPSD	COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q9Y6K1	DNMT3A	P28482	MAPK1	T261	P256L	256	Missense	distal	-5	no	13.031	13.180	EPSD	COSMIC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q9Y6K1	DNMT3A	P28482	MAPK1	T261	P256S	256	Missense	distal	-5	no	13.031	13.105	EPSD	COSMIC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q9Y6K1	DNMT3A	P28482	MAPK1	T261	S267F	267	Missense	distal	6	no	13.031	12.590	EPSD	COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q9Y6K1	DNMT3A	P28482	MAPK1	T261	P264L	264	Missense	distal	3	no	13.031	13.120	EPSD	COSMIC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q9Y6K1	DNMT3A	P28482	MAPK1	T261	D268N	268	Missense	distal	7	no	13.031	13.017	EPSD	COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q9Y6K1	DNMT3A	P28482	MAPK1	T261	P264S	264	Missense	distal	3	no	13.031	13.100	EPSD	COSMIC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q9UBN7	HDAC6	P28482	MAPK1	S16	P20R	20	Missense	distal	4	no	8.614	8.581	EPSD	COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q9UBN7	HDAC6	P28482	MAPK1	S22	Q25R	25	Missense	distal	3	no	18.704	18.682	EPSD	COSMIC;CCLE	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q9UBN7	HDAC6	P28482	MAPK1	S22	P20R	20	Missense	proximal	-2	no	18.704	16.886	EPSD	COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q9UBN7	HDAC6	P28482	MAPK1	S412	P416S	416	Missense	distal	4	no	14.167	14.156	EPSD	COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q9UBN7	HDAC6	P28482	MAPK1	T527	P528Q	528	Missense	proximal	1	no	12.432	3.938	EPSD	COSMIC	8.102	Loss
CMGC_MAPK_ERK1_MAPK1_ST	Q9UBN7	HDAC6	P28482	MAPK1	T527	G521R	521	Missense	distal	-6	no	12.432	12.483	EPSD	COSMIC;GDSC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q9UBN7	HDAC6	P28482	MAPK1	T527	R529C	529	Missense	proximal	2	no	12.432	12.059	EPSD	COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q9UBN7	HDAC6	P28482	MAPK1	T551	R549P	549	Missense	proximal	-2	no	7.776	9.595	EPSD	COSMIC;CCLE	8.102	Gain
CMGC_MAPK_ERK1_MAPK1_ST	Q9UBN7	HDAC6	P28482	MAPK1	T1021	S1026I	1026	Missense	distal	5	no	14.144	13.826	EPSD	COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q9UBN7	HDAC6	P28482	MAPK1	T1021	S1025L	1025	Missense	distal	4	no	14.144	14.034	EPSD	COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q9UBN7	HDAC6	P28482	MAPK1	T1021	G1014W	1014	Missense	distal	-7	no	14.144	14.106	EPSD	COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q9UBN7	HDAC6	P28482	MAPK1	T1021	T1016N	1016	Missense	distal	-5	no	14.144	14.067	EPSD	COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q9UBN7	HDAC6	P28482	MAPK1	T1031	P1032L	1032	Missense	proximal	1	no	13.802	4.992	PhosphoSitePlus	COSMIC	8.102	Loss
CMGC_MAPK_ERK1_MAPK1_ST	Q9UBN7	HDAC6	P28482	MAPK1	T1031	S1026I	1026	Missense	distal	-5	no	13.802	13.937	PhosphoSitePlus	COSMIC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q9UBN7	HDAC6	P28482	MAPK1	T1031	S1025L	1025	Missense	distal	-6	no	13.802	13.736	PhosphoSitePlus	COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q9UBN7	HDAC6	P28482	MAPK1	T1034	P1032L	1032	Missense	proximal	-2	no	8.515	6.598	EPSD	COSMIC	8.102	Loss
CMGC_MAPK_ERK1_MAPK1_ST	Q9UBN7	HDAC6	P28482	MAPK1	T1034	T1040P	1040	Missense	distal	6	no	8.515	8.725	EPSD	COSMIC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q9UBN7	HDAC6	P28482	MAPK1	S1035	P1032L	1032	Missense	distal	-3	no	16.449	16.065	EPSD	COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q9UBN7	HDAC6	P28482	MAPK1	S1035	T1040P	1040	Missense	distal	5	no	16.449	16.504	EPSD	COSMIC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q9UBN7	HDAC6	P28482	MAPK1	T1041	I1044M	1044	Missense	distal	3	no	11.481	11.438	EPSD	COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q9UBN7	HDAC6	P28482	MAPK1	T1041	T1040P	1040	Missense	proximal	-1	no	11.481	11.523	EPSD	COSMIC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q9UBN7	HDAC6	P28482	MAPK1	T1048	I1044M	1044	Missense	distal	-4	no	7.899	8.104	EPSD	COSMIC	8.102	Gain
CMGC_MAPK_ERK1_MAPK1_ST	P33981	TTK	P28482	MAPK1	S80	P78L	78	Missense	proximal	-2	no	9.018	7.101	EPSD	COSMIC	8.102	Loss
CMGC_MAPK_ERK1_MAPK1_ST	P33981	TTK	P28482	MAPK1	S80	P78Q	78	Missense	proximal	-2	no	9.018	6.024	EPSD	COSMIC	8.102	Loss
CMGC_MAPK_ERK1_MAPK1_ST	P33981	TTK	P28482	MAPK1	S214	V208A	208	Missense	distal	-6	no	8.447	8.494	EPSD	COSMIC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P33981	TTK	P28482	MAPK1	S382	N383S	383	Missense	proximal	1	no	-1.705	8.623	EPSD	COSMIC	8.102	Gain
CMGC_MAPK_ERK1_MAPK1_ST	P33981	TTK	P28482	MAPK1	S436	T441I	441	Missense	distal	5	no	13.874	13.631	EPSD	COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P33981	TTK	P28482	MAPK1	S440	T441I	441	Missense	proximal	1	no	9.872	8.553	EPSD	COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P33981	TTK	P28482	MAPK1	T453	S455N	455	Missense	proximal	2	no	8.512	8.463	EPSD	COSMIC;GDSC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P33981	TTK	P28482	MAPK1	T453	T458A	458	Missense	distal	5	no	8.512	8.426	EPSD	COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P33981	TTK	P28482	MAPK1	T453	K452N	452	Missense	proximal	-1	no	8.512	8.504	EPSD	COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P33981	TTK	P28482	MAPK1	T453	K452E	452	Missense	proximal	-1	no	8.512	8.484	EPSD	COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P33981	TTK	P28482	MAPK1	T453	S455R	455	Missense	proximal	2	no	8.512	8.653	EPSD	COSMIC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P33981	TTK	P28482	MAPK1	T453	S455I	455	Missense	proximal	2	no	8.512	8.368	EPSD	COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P33981	TTK	P28482	MAPK1	S464	C465F	465	Missense	proximal	1	no	1.242	8.121	EPSD	COSMIC	8.102	Gain
CMGC_MAPK_ERK1_MAPK1_ST	P33981	TTK	P28482	MAPK1	T468	D474N	474	Missense	distal	6	no	12.759	12.709	EPSD	COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P33981	TTK	P28482	MAPK1	T468	C465F	465	Missense	distal	-3	no	12.759	13.054	EPSD	COSMIC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P33981	TTK	P28482	MAPK1	T468	T468A	468	Missense	central	0	yes	12.759	0.000	EPSD	COSMIC	8.102	Loss
CMGC_MAPK_ERK1_MAPK1_ST	P33981	TTK	P28482	MAPK1	T468	M463T	463	Missense	distal	-5	no	12.759	12.710	EPSD	COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P33981	TTK	P28482	MAPK1	S582	I586V	586	Missense	distal	4	no	8.052	8.119	EPSD	COSMIC	8.102	Gain
CMGC_MAPK_ERK1_MAPK1_ST	P33981	TTK	P28482	MAPK1	S582	I586T	586	Missense	distal	4	no	8.052	8.105	EPSD	COSMIC	8.102	Gain
CMGC_MAPK_ERK1_MAPK1_ST	P33981	TTK	P28482	MAPK1	S821	P822S	822	Missense	proximal	1	no	13.032	3.637	PhosphoSitePlus	COSMIC	8.102	Loss
CMGC_MAPK_ERK1_MAPK1_ST	P33981	TTK	P28482	MAPK1	S821	A828V	828	Missense	distal	7	no	13.032	13.134	PhosphoSitePlus	COSMIC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P33981	TTK	P28482	MAPK1	S821	N823H	823	Missense	proximal	2	no	13.032	12.978	PhosphoSitePlus	COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P33981	TTK	P28482	MAPK1	S844	K848R	848	Missense	distal	4	no	9.015	9.005	EPSD	COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P33981	TTK	P28482	MAPK1	S844	N843I	843	Missense	proximal	-1	no	9.015	8.944	EPSD	COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P33981	TTK	P28482	MAPK1	S847	K848R	848	Missense	proximal	1	no	-0.608	8.257	EPSD	COSMIC	8.102	Gain
CMGC_MAPK_ERK1_MAPK1_ST	P33981	TTK	P28482	MAPK1	T849	G855E	855	Missense	distal	6	no	8.037	8.147	EPSD	COSMIC;CCLE	8.102	Gain
CMGC_MAPK_ERK1_MAPK1_ST	P33981	TTK	P28482	MAPK1	T849	K852Q	852	Missense	distal	3	no	8.037	8.107	EPSD	COSMIC	8.102	Gain
CMGC_MAPK_ERK1_MAPK1_ST	Q86UR1	NOXA1	P28482	MAPK1	S239	R241I	241	Missense	proximal	2	no	9.791	9.506	EPSD	COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q86UR1	NOXA1	P28482	MAPK1	S239	P240Q	240	Missense	proximal	1	no	9.791	1.297	EPSD	COSMIC	8.102	Loss
CMGC_MAPK_ERK1_MAPK1_ST	Q86UR1	NOXA1	P28482	MAPK1	S239	S234P	234	Missense	distal	-5	no	9.791	9.716	EPSD	COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q86UR1	NOXA1	P28482	MAPK1	S239	H245Y	245	Missense	distal	6	no	9.791	9.477	EPSD	COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q86UR1	NOXA1	P28482	MAPK1	S239	S239P	239	Missense	central	0	yes	9.791	0.000	EPSD	COSMIC	8.102	Loss
CMGC_MAPK_ERK1_MAPK1_ST	Q86UR1	NOXA1	P28482	MAPK1	S282	P286L	286	Missense	distal	4	no	15.873	15.753	PhosphoSitePlus	COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P47712	PLA2G4A	P28482	MAPK1	T41	P44L	44	Missense	distal	3	no	16.542	16.632	EPSD	COSMIC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P47712	PLA2G4A	P28482	MAPK1	T53	P54T	54	Missense	proximal	1	no	15.064	6.565	EPSD	COSMIC	8.102	Loss
CMGC_MAPK_ERK1_MAPK1_ST	P47712	PLA2G4A	P28482	MAPK1	S56	P54T	54	Missense	proximal	-2	no	8.269	5.569	EPSD	COSMIC	8.102	Loss
CMGC_MAPK_ERK1_MAPK1_ST	P47712	PLA2G4A	P28482	MAPK1	T268	P263L	263	Missense	distal	-5	no	13.910	14.059	EPSD	COSMIC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P47712	PLA2G4A	P28482	MAPK1	T268	H261Q	261	Missense	distal	-7	no	13.910	13.929	EPSD	COSMIC;GDSC;CCLE	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P47712	PLA2G4A	P28482	MAPK1	S505	D509G	509	Missense	distal	4	no	15.768	15.816	PhosphoSitePlus	COSMIC;GDSC;CCLE	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P47712	PLA2G4A	P28482	MAPK1	S505	P503L	503	Missense	proximal	-2	no	15.768	13.851	PhosphoSitePlus	COSMIC;GDSC;CCLE	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P47712	PLA2G4A	P28482	MAPK1	S508	D509G	509	Missense	proximal	1	no	8.279	6.910	EPSD	COSMIC;GDSC;CCLE	8.102	Loss
CMGC_MAPK_ERK1_MAPK1_ST	P47712	PLA2G4A	P28482	MAPK1	S508	P503L	503	Missense	distal	-5	no	8.279	8.428	EPSD	COSMIC;GDSC;CCLE	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P47712	PLA2G4A	P28482	MAPK1	S515	D509G	509	Missense	distal	-6	no	8.506	8.440	EPSD	COSMIC;GDSC;CCLE	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P47712	PLA2G4A	P28482	MAPK1	S515	D519G	519	Missense	distal	4	no	8.506	8.554	EPSD	COSMIC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q12931	TRAP1	P28482	MAPK1	T40	R37W	37	Missense	distal	-3	no	8.206	7.508	EPSD	COSMIC	8.102	Loss
CMGC_MAPK_ERK1_MAPK1_ST	Q12931	TRAP1	P28482	MAPK1	T40	P36L	36	Missense	distal	-4	no	8.206	7.902	EPSD	COSMIC	8.102	Loss
CMGC_MAPK_ERK1_MAPK1_ST	Q12931	TRAP1	P28482	MAPK1	S282	F280L	280	Missense	proximal	-2	no	9.403	10.127	EPSD	COSMIC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P19419	ELK1	P28482	MAPK1	T133	P131Q	131	Missense	proximal	-2	no	14.506	11.513	EPSD	COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P19419	ELK1	P28482	MAPK1	T133	K130N	130	Missense	distal	-3	no	14.506	14.603	EPSD	COSMIC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P19419	ELK1	P28482	MAPK1	T133	P134S	134	Missense	proximal	1	no	14.506	5.112	EPSD	COSMIC	8.102	Loss
CMGC_MAPK_ERK1_MAPK1_ST	P19419	ELK1	P28482	MAPK1	S304	P305S	305	Missense	proximal	1	no	13.262	3.867	EPSD	COSMIC	8.102	Loss
CMGC_MAPK_ERK1_MAPK1_ST	P19419	ELK1	P28482	MAPK1	S304	Q309R	309	Missense	distal	5	no	13.262	13.432	EPSD	COSMIC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P19419	ELK1	P28482	MAPK1	T336	R335W	335	Missense	proximal	-1	no	13.215	13.114	EPSD	COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P19419	ELK1	P28482	MAPK1	T353	Q346H	346	Missense	distal	-7	no	12.838	12.819	EPSD	COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P19419	ELK1	P28482	MAPK1	T353	A351G	351	Missense	proximal	-2	no	12.838	12.791	EPSD	COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P19419	ELK1	P28482	MAPK1	S383	R388C	388	Missense	distal	5	no	13.857	13.426	PhosphoSitePlus	COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P19419	ELK1	P28482	MAPK1	S383	S380I	380	Missense	distal	-3	no	13.857	13.592	PhosphoSitePlus	COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P19419	ELK1	P28482	MAPK1	S389	S394P	394	Missense	distal	5	no	13.963	13.945	EPSD	COSMIC;GDSC;CCLE	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P19419	ELK1	P28482	MAPK1	S389	R388C	388	Missense	proximal	-1	no	13.963	13.861	EPSD	COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P19419	ELK1	P28482	MAPK1	S389	S394F	394	Missense	distal	5	no	13.963	13.766	EPSD	COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P19419	ELK1	P28482	MAPK1	S422	P425S	425	Missense	distal	3	no	18.830	18.899	EPSD	COSMIC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q92908	GATA6	P28482	MAPK1	T62	A57D	57	Missense	distal	-5	no	9.735	9.680	EPSD	COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q92908	GATA6	P28482	MAPK1	S436	S437P	437	Missense	proximal	1	no	8.986	18.381	EPSD	COSMIC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q92908	GATA6	P28482	MAPK1	S436	R438Q	438	Missense	proximal	2	no	8.986	8.694	EPSD	COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q92908	GATA6	P28482	MAPK1	T515	S518F	518	Missense	distal	3	no	15.246	15.308	EPSD	COSMIC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q92908	GATA6	P28482	MAPK1	S531	T537A	537	Missense	distal	6	no	13.901	13.815	EPSD	COSMIC;GDSC;CCLE	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q92908	GATA6	P28482	MAPK1	S531	S531Y	531	Missense	central	0	yes	13.901	0.000	EPSD	COSMIC	8.102	Loss
CMGC_MAPK_ERK1_MAPK1_ST	Q92908	GATA6	P28482	MAPK1	T534	T537A	537	Missense	distal	3	no	9.999	10.015	EPSD	COSMIC;GDSC;CCLE	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q92908	GATA6	P28482	MAPK1	T534	A541V	541	Missense	distal	7	no	9.999	10.100	EPSD	COSMIC;GDSC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q92908	GATA6	P28482	MAPK1	T534	S531Y	531	Missense	distal	-3	no	9.999	9.729	EPSD	COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P04637	TP53	P28482	MAPK1	S6	D7H	7	Missense	proximal	1	no	7.553	8.426	EPSD	COSMIC	8.102	Gain
CMGC_MAPK_ERK1_MAPK1_ST	P04637	TP53	P28482	MAPK1	S6	D7Y	7	Missense	proximal	1	no	7.553	9.240	EPSD	COSMIC	8.102	Gain
CMGC_MAPK_ERK1_MAPK1_ST	P04637	TP53	P28482	MAPK1	S15	E11Q	11	Missense	distal	-4	no	12.725	12.561	PhosphoSitePlus;EPSD	COSMIC;GDSC;CCLE	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P04637	TP53	P28482	MAPK1	S15	S20L	20	Missense	distal	5	no	12.725	12.494	PhosphoSitePlus;EPSD	COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P04637	TP53	P28482	MAPK1	S15	Q16L	16	Missense	proximal	1	no	12.725	12.409	PhosphoSitePlus;EPSD	COSMIC;GDSC;CCLE	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P04637	TP53	P28482	MAPK1	S15	P13S	13	Missense	proximal	-2	no	12.725	9.891	PhosphoSitePlus;EPSD	COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P04637	TP53	P28482	MAPK1	S15	V10I	10	Missense	distal	-5	no	12.725	12.838	PhosphoSitePlus;EPSD	COSMIC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P04637	TP53	P28482	MAPK1	S15	P8L	8	Missense	distal	-7	no	12.725	12.713	PhosphoSitePlus;EPSD	COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P04637	TP53	P28482	MAPK1	S15	P8S	8	Missense	distal	-7	no	12.725	12.721	PhosphoSitePlus;EPSD	COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P04637	TP53	P28482	MAPK1	S15	P13L	13	Missense	proximal	-2	no	12.725	10.808	PhosphoSitePlus;EPSD	COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P04637	TP53	P28482	MAPK1	S15	V10G	10	Missense	distal	-5	no	12.725	12.697	PhosphoSitePlus;EPSD	COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P04637	TP53	P28482	MAPK1	S15	T18A	18	Missense	distal	3	no	12.725	12.741	PhosphoSitePlus;EPSD	COSMIC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P04637	TP53	P28482	MAPK1	S15	F19S	19	Missense	distal	4	no	12.725	12.903	PhosphoSitePlus;EPSD	COSMIC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P04637	TP53	P28482	MAPK1	S15	E17V	17	Missense	proximal	2	no	12.725	12.739	PhosphoSitePlus;EPSD	COSMIC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P04637	TP53	P28482	MAPK1	S15	S9G	9	Missense	distal	-6	no	12.725	12.708	PhosphoSitePlus;EPSD	COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P04637	TP53	P28482	MAPK1	S15	T18I	18	Missense	distal	3	no	12.725	12.791	PhosphoSitePlus;EPSD	COSMIC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P04637	TP53	P28482	MAPK1	S15	T18K	18	Missense	distal	3	no	12.725	12.661	PhosphoSitePlus;EPSD	COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P04637	TP53	P28482	MAPK1	S15	T18R	18	Missense	distal	3	no	12.725	12.709	PhosphoSitePlus;EPSD	COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P04637	TP53	P28482	MAPK1	S15	S15I	15	Missense	central	0	yes	12.725	0.000	PhosphoSitePlus;EPSD	COSMIC	8.102	Loss
CMGC_MAPK_ERK1_MAPK1_ST	P04637	TP53	P28482	MAPK1	T18	E11Q	11	Missense	distal	-7	no	9.122	9.120	EPSD	COSMIC;GDSC;CCLE	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P04637	TP53	P28482	MAPK1	T18	S20L	20	Missense	proximal	2	no	9.122	9.003	EPSD	COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P04637	TP53	P28482	MAPK1	T18	Q16L	16	Missense	proximal	-2	no	9.122	10.199	EPSD	COSMIC;GDSC;CCLE	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P04637	TP53	P28482	MAPK1	T18	P13S	13	Missense	distal	-5	no	9.122	9.196	EPSD	COSMIC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P04637	TP53	P28482	MAPK1	T18	E17K	17	Missense	proximal	-1	no	9.122	9.150	EPSD	COSMIC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P04637	TP53	P28482	MAPK1	T18	P13L	13	Missense	distal	-5	no	9.122	9.271	EPSD	COSMIC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P04637	TP53	P28482	MAPK1	T18	T18A	18	Missense	central	0	yes	9.122	0.000	EPSD	COSMIC	8.102	Loss
CMGC_MAPK_ERK1_MAPK1_ST	P04637	TP53	P28482	MAPK1	T18	F19S	19	Missense	proximal	1	no	9.122	6.297	EPSD	COSMIC	8.102	Loss
CMGC_MAPK_ERK1_MAPK1_ST	P04637	TP53	P28482	MAPK1	T18	E17V	17	Missense	proximal	-1	no	9.122	9.111	EPSD	COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P04637	TP53	P28482	MAPK1	T18	T18I	18	Missense	central	0	yes	9.122	0.000	EPSD	COSMIC	8.102	Loss
CMGC_MAPK_ERK1_MAPK1_ST	P04637	TP53	P28482	MAPK1	T18	T18K	18	Missense	central	0	yes	9.122	0.000	EPSD	COSMIC	8.102	Loss
CMGC_MAPK_ERK1_MAPK1_ST	P04637	TP53	P28482	MAPK1	T18	T18R	18	Missense	central	0	yes	9.122	0.000	EPSD	COSMIC	8.102	Loss
CMGC_MAPK_ERK1_MAPK1_ST	P04637	TP53	P28482	MAPK1	T18	S15I	15	Missense	distal	-3	no	9.122	8.858	EPSD	COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P04637	TP53	P28482	MAPK1	S20	L26P	26	Missense	distal	6	no	7.783	8.189	EPSD	COSMIC	8.102	Gain
CMGC_MAPK_ERK1_MAPK1_ST	P04637	TP53	P28482	MAPK1	S20	T18I	18	Missense	proximal	-2	no	7.783	8.588	EPSD	COSMIC	8.102	Gain
CMGC_MAPK_ERK1_MAPK1_ST	P04637	TP53	P28482	MAPK1	S20	T18R	18	Missense	proximal	-2	no	7.783	8.664	EPSD	COSMIC	8.102	Gain
CMGC_MAPK_ERK1_MAPK1_ST	P04637	TP53	P28482	MAPK1	S33	M40I	40	Missense	distal	7	no	13.820	14.008	EPSD	COSMIC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P04637	TP53	P28482	MAPK1	S33	V31I	31	Missense	proximal	-2	no	13.820	13.798	EPSD	COSMIC;GDSC;CCLE	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P04637	TP53	P28482	MAPK1	S33	P36L	36	Missense	distal	3	no	13.820	13.909	EPSD	COSMIC;GDSC;CCLE	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P04637	TP53	P28482	MAPK1	S33	L35F	35	Missense	proximal	2	no	13.820	13.808	EPSD	COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P04637	TP53	P28482	MAPK1	S33	Q38L	38	Missense	distal	5	no	13.820	13.727	EPSD	COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P04637	TP53	P28482	MAPK1	S33	S37T	37	Missense	distal	4	no	13.820	13.707	EPSD	COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P04637	TP53	P28482	MAPK1	S33	L26P	26	Missense	distal	-7	no	13.820	13.832	EPSD	COSMIC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P04637	TP53	P28482	MAPK1	S33	P36S	36	Missense	distal	3	no	13.820	13.889	EPSD	COSMIC;GDSC;CCLE	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P04637	TP53	P28482	MAPK1	S33	A39V	39	Missense	distal	6	no	13.820	13.901	EPSD	COSMIC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P04637	TP53	P28482	MAPK1	S33	A39S	39	Missense	distal	6	no	13.820	14.116	EPSD	COSMIC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P04637	TP53	P28482	MAPK1	S33	N30K	30	Missense	distal	-3	no	13.820	13.723	EPSD	COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P04637	TP53	P28482	MAPK1	S33	A39T	39	Missense	distal	6	no	13.820	13.906	EPSD	COSMIC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P04637	TP53	P28482	MAPK1	S33	P27T	27	Missense	distal	-6	no	13.820	13.770	EPSD	COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P04637	TP53	P28482	MAPK1	S33	P36R	36	Missense	distal	3	no	13.820	13.866	EPSD	COSMIC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P04637	TP53	P28482	MAPK1	S33	L35R	35	Missense	proximal	2	no	13.820	14.081	EPSD	COSMIC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P04637	TP53	P28482	MAPK1	S33	L35H	35	Missense	proximal	2	no	13.820	13.838	EPSD	COSMIC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P04637	TP53	P28482	MAPK1	S33	L35P	35	Missense	proximal	2	no	13.820	13.967	EPSD	COSMIC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P04637	TP53	P28482	MAPK1	S33	L35I	35	Missense	proximal	2	no	13.820	13.796	EPSD	COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P04637	TP53	P28482	MAPK1	S33	L35V	35	Missense	proximal	2	no	13.820	13.914	EPSD	COSMIC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P04637	TP53	P28482	MAPK1	S46	M40I	40	Missense	distal	-6	no	11.716	11.672	EPSD	COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P04637	TP53	P28482	MAPK1	S46	W53C	53	Missense	distal	7	no	11.716	11.399	EPSD	COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P04637	TP53	P28482	MAPK1	S46	W53G	53	Missense	distal	7	no	11.716	10.809	EPSD	COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P04637	TP53	P28482	MAPK1	S46	S46F	46	Missense	central	0	yes	11.716	0.000	EPSD	COSMIC	8.102	Loss
CMGC_MAPK_ERK1_MAPK1_ST	P04637	TP53	P28482	MAPK1	S46	D49Y	49	Missense	distal	3	no	11.716	11.757	EPSD	COSMIC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P04637	TP53	P28482	MAPK1	S46	P47L	47	Missense	proximal	1	no	11.716	2.906	EPSD	COSMIC	8.102	Loss
CMGC_MAPK_ERK1_MAPK1_ST	P04637	TP53	P28482	MAPK1	S46	D49H	49	Missense	distal	3	no	11.716	11.718	EPSD	COSMIC;GDSC;CCLE	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P04637	TP53	P28482	MAPK1	S46	P47S	47	Missense	proximal	1	no	11.716	2.321	EPSD	COSMIC	8.102	Loss
CMGC_MAPK_ERK1_MAPK1_ST	P04637	TP53	P28482	MAPK1	S46	D41N	41	Missense	distal	-5	no	11.716	11.671	EPSD	COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P04637	TP53	P28482	MAPK1	S46	D48H	48	Missense	proximal	2	no	11.716	11.602	EPSD	COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P04637	TP53	P28482	MAPK1	S46	D49N	49	Missense	distal	3	no	11.716	11.620	EPSD	COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P04637	TP53	P28482	MAPK1	S46	M44I	44	Missense	proximal	-2	no	11.716	13.836	EPSD	COSMIC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P04637	TP53	P28482	MAPK1	S46	Q52H	52	Missense	distal	6	no	11.716	11.698	EPSD	COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P04637	TP53	P28482	MAPK1	S46	D49V	49	Missense	distal	3	no	11.716	11.687	EPSD	COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P04637	TP53	P28482	MAPK1	S46	A39V	39	Missense	distal	-7	no	11.716	11.699	EPSD	COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P04637	TP53	P28482	MAPK1	S46	A39S	39	Missense	distal	-7	no	11.716	11.714	EPSD	COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P04637	TP53	P28482	MAPK1	S46	D42Y	42	Missense	distal	-4	no	11.716	11.057	EPSD	COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P04637	TP53	P28482	MAPK1	S46	M44R	44	Missense	proximal	-2	no	11.716	13.911	EPSD	COSMIC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P04637	TP53	P28482	MAPK1	S46	S46P	46	Missense	central	0	yes	11.716	0.000	EPSD	COSMIC	8.102	Loss
CMGC_MAPK_ERK1_MAPK1_ST	P04637	TP53	P28482	MAPK1	S46	M44V	44	Missense	proximal	-2	no	11.716	13.857	EPSD	COSMIC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P04637	TP53	P28482	MAPK1	S46	L45P	45	Missense	proximal	-1	no	11.716	11.776	EPSD	COSMIC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P04637	TP53	P28482	MAPK1	S46	M44T	44	Missense	proximal	-2	no	11.716	13.031	EPSD	COSMIC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P04637	TP53	P28482	MAPK1	S46	A39T	39	Missense	distal	-7	no	11.716	11.701	EPSD	COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P04637	TP53	P28482	MAPK1	S46	L43F	43	Missense	distal	-3	no	11.716	11.691	EPSD	COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P04637	TP53	P28482	MAPK1	S46	D41H	41	Missense	distal	-5	no	11.716	11.770	EPSD	COSMIC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P04637	TP53	P28482	MAPK1	S46	D49E	49	Missense	distal	3	no	11.716	11.620	EPSD	COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P04637	TP53	P28482	MAPK1	S46	D49G	49	Missense	distal	3	no	11.716	11.713	EPSD	COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P04637	TP53	P28482	MAPK1	S46	D48A	48	Missense	proximal	2	no	11.716	11.602	EPSD	COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P04637	TP53	P28482	MAPK1	S46	D48Y	48	Missense	proximal	2	no	11.716	11.536	EPSD	COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P04637	TP53	P28482	MAPK1	S46	D48E	48	Missense	proximal	2	no	11.716	11.664	EPSD	COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P04637	TP53	P28482	MAPK1	S46	D49I	49	Missense	distal	3	no	11.716	11.757	EPSD	COSMIC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P04637	TP53	P28482	MAPK1	S46	D41E	41	Missense	distal	-5	no	11.716	11.671	EPSD	COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P04637	TP53	P28482	MAPK1	T81	P77A	77	Missense	distal	-4	no	14.705	14.412	EPSD	COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P04637	TP53	P28482	MAPK1	T81	A76T	76	Missense	distal	-5	no	14.705	14.683	EPSD	COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P04637	TP53	P28482	MAPK1	T81	A83T	83	Missense	proximal	2	no	14.705	14.784	EPSD	COSMIC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P04637	TP53	P28482	MAPK1	T81	T81I	81	Missense	central	0	yes	14.705	0.000	EPSD	COSMIC	8.102	Loss
CMGC_MAPK_ERK1_MAPK1_ST	P04637	TP53	P28482	MAPK1	T81	A84V	84	Missense	distal	3	no	14.705	14.685	EPSD	COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P04637	TP53	P28482	MAPK1	T81	P80L	80	Missense	proximal	-1	no	14.705	14.645	EPSD	COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P04637	TP53	P28482	MAPK1	T81	A86V	86	Missense	distal	5	no	14.705	14.722	EPSD	COSMIC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P04637	TP53	P28482	MAPK1	T81	P85S	85	Missense	distal	4	no	14.705	14.695	EPSD	COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P04637	TP53	P28482	MAPK1	T81	A79T	79	Missense	proximal	-2	no	14.705	15.153	EPSD	COSMIC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P04637	TP53	P28482	MAPK1	T81	A84G	84	Missense	distal	3	no	14.705	14.711	EPSD	COSMIC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P04637	TP53	P28482	MAPK1	T81	A78V	78	Missense	distal	-3	no	14.705	14.765	EPSD	COSMIC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P04637	TP53	P28482	MAPK1	T81	A78S	78	Missense	distal	-3	no	14.705	14.896	EPSD	COSMIC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P04637	TP53	P28482	MAPK1	T81	P87L	87	Missense	distal	6	no	14.705	14.299	EPSD	COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P04637	TP53	P28482	MAPK1	T81	P85L	85	Missense	distal	4	no	14.705	14.585	EPSD	COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P04637	TP53	P28482	MAPK1	T81	P82S	82	Missense	proximal	1	no	14.705	5.310	EPSD	COSMIC	8.102	Loss
CMGC_MAPK_ERK1_MAPK1_ST	P04637	TP53	P28482	MAPK1	T81	P77S	77	Missense	distal	-4	no	14.705	14.621	EPSD	COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P04637	TP53	P28482	MAPK1	T81	P80S	80	Missense	proximal	-1	no	14.705	14.662	EPSD	COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P04637	TP53	P28482	MAPK1	T81	A84T	84	Missense	distal	3	no	14.705	14.689	EPSD	COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P04637	TP53	P28482	MAPK1	T81	A83E	83	Missense	proximal	2	no	14.705	14.768	EPSD	COSMIC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P04637	TP53	P28482	MAPK1	T81	P85T	85	Missense	distal	4	no	14.705	14.582	EPSD	COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P04637	TP53	P28482	MAPK1	T81	A74V	74	Missense	distal	-7	no	14.705	14.689	EPSD	COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P04637	TP53	P28482	MAPK1	T81	P75S	75	Missense	distal	-6	no	14.705	14.679	EPSD	COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P04637	TP53	P28482	MAPK1	T81	A76V	76	Missense	distal	-5	no	14.705	14.677	EPSD	COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P04637	TP53	P28482	MAPK1	T81	P75R	75	Missense	distal	-6	no	14.705	14.713	EPSD	COSMIC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P04637	TP53	P28482	MAPK1	T81	P87H	87	Missense	distal	6	no	14.705	14.400	EPSD	COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P04637	TP53	P28482	MAPK1	T81	P87T	87	Missense	distal	6	no	14.705	14.495	EPSD	COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P04637	TP53	P28482	MAPK1	T81	P87R	87	Missense	distal	6	no	14.705	14.598	EPSD	COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P04637	TP53	P28482	MAPK1	T81	P87C	87	Missense	distal	6	no	14.705	13.838	EPSD	COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P04637	TP53	P28482	MAPK1	T81	A86E	86	Missense	distal	5	no	14.705	14.821	EPSD	COSMIC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P04637	TP53	P28482	MAPK1	T81	A86S	86	Missense	distal	5	no	14.705	14.865	EPSD	COSMIC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P04637	TP53	P28482	MAPK1	T81	A83V	83	Missense	proximal	2	no	14.705	14.781	EPSD	COSMIC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P04637	TP53	P28482	MAPK1	S127	C124W	124	Missense	distal	-3	no	14.148	14.133	EPSD	COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P04637	TP53	P28482	MAPK1	S127	C124F	124	Missense	distal	-3	no	14.148	14.442	EPSD	COSMIC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P04637	TP53	P28482	MAPK1	S127	C124S	124	Missense	distal	-3	no	14.148	14.675	EPSD	COSMIC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P04637	TP53	P28482	MAPK1	S127	S127A	127	Missense	central	0	yes	14.148	0.000	EPSD	COSMIC	8.102	Loss
CMGC_MAPK_ERK1_MAPK1_ST	P04637	TP53	P28482	MAPK1	S127	S127L	127	Missense	central	0	yes	14.148	0.000	EPSD	COSMIC	8.102	Loss
CMGC_MAPK_ERK1_MAPK1_ST	P04637	TP53	P28482	MAPK1	S127	C124T	124	Missense	distal	-3	no	14.148	14.642	EPSD	COSMIC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P04637	TP53	P28482	MAPK1	S127	S127I	127	Missense	central	0	yes	14.148	0.000	EPSD	COSMIC	8.102	Loss
CMGC_MAPK_ERK1_MAPK1_ST	P04637	TP53	P28482	MAPK1	S127	S127G	127	Missense	central	0	yes	14.148	0.000	EPSD	COSMIC	8.102	Loss
CMGC_MAPK_ERK1_MAPK1_ST	P04637	TP53	P28482	MAPK1	S127	N131H	131	Missense	distal	4	no	14.148	14.021	EPSD	COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P04637	TP53	P28482	MAPK1	S127	N131D	131	Missense	distal	4	no	14.148	14.088	EPSD	COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P04637	TP53	P28482	MAPK1	S127	T125I	125	Missense	proximal	-2	no	14.148	14.953	EPSD	COSMIC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P04637	TP53	P28482	MAPK1	S127	F134I	134	Missense	distal	7	no	14.148	14.348	EPSD	COSMIC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P04637	TP53	P28482	MAPK1	S127	K120T	120	Missense	distal	-7	no	14.148	14.133	EPSD	COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P04637	TP53	P28482	MAPK1	S127	F134S	134	Missense	distal	7	no	14.148	13.800	EPSD	COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P04637	TP53	P28482	MAPK1	S127	T125K	125	Missense	proximal	-2	no	14.148	14.428	EPSD	COSMIC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P04637	TP53	P28482	MAPK1	S127	M133I	133	Missense	distal	6	no	14.148	13.914	EPSD	COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P04637	TP53	P28482	MAPK1	S127	N131K	131	Missense	distal	4	no	14.148	14.173	EPSD	COSMIC;CCLE	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P04637	TP53	P28482	MAPK1	S127	P128S	128	Missense	proximal	1	no	14.148	4.753	EPSD	COSMIC	8.102	Loss
CMGC_MAPK_ERK1_MAPK1_ST	P04637	TP53	P28482	MAPK1	S127	M133L	133	Missense	distal	6	no	14.148	14.174	EPSD	COSMIC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P04637	TP53	P28482	MAPK1	S127	A129T	129	Missense	proximal	2	no	14.148	14.227	EPSD	COSMIC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P04637	TP53	P28482	MAPK1	S127	T123I	123	Missense	distal	-4	no	14.148	13.791	EPSD	COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P04637	TP53	P28482	MAPK1	S127	A129G	129	Missense	proximal	2	no	14.148	14.296	EPSD	COSMIC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P04637	TP53	P28482	MAPK1	S127	K132W	132	Missense	distal	5	no	14.148	13.754	EPSD	COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P04637	TP53	P28482	MAPK1	S127	A129V	129	Missense	proximal	2	no	14.148	14.224	EPSD	COSMIC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P04637	TP53	P28482	MAPK1	S127	P128A	128	Missense	proximal	1	no	14.148	6.517	EPSD	COSMIC	8.102	Loss
CMGC_MAPK_ERK1_MAPK1_ST	P04637	TP53	P28482	MAPK1	S127	L130I	130	Missense	distal	3	no	14.148	14.186	EPSD	COSMIC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P04637	TP53	P28482	MAPK1	S127	S121F	121	Missense	distal	-6	no	14.148	14.064	EPSD	COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P04637	TP53	P28482	MAPK1	S127	A129D	129	Missense	proximal	2	no	14.148	14.262	EPSD	COSMIC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P04637	TP53	P28482	MAPK1	S127	K120Q	120	Missense	distal	-7	no	14.148	14.153	EPSD	COSMIC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P04637	TP53	P28482	MAPK1	S127	T125S	125	Missense	proximal	-2	no	14.148	14.013	EPSD	COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P04637	TP53	P28482	MAPK1	S127	P128L	128	Missense	proximal	1	no	14.148	5.338	EPSD	COSMIC	8.102	Loss
CMGC_MAPK_ERK1_MAPK1_ST	P04637	TP53	P28482	MAPK1	S127	V122L	122	Missense	distal	-5	no	14.148	14.201	EPSD	COSMIC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P04637	TP53	P28482	MAPK1	S127	C124L	124	Missense	distal	-3	no	14.148	14.467	EPSD	COSMIC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P04637	TP53	P28482	MAPK1	S127	N131T	131	Missense	distal	4	no	14.148	14.072	EPSD	COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P04637	TP53	P28482	MAPK1	S127	M133V	133	Missense	distal	6	no	14.148	14.366	EPSD	COSMIC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P04637	TP53	P28482	MAPK1	T150	P151N	151	Missense	proximal	1	no	11.263	-8.460	EPSD	COSMIC	8.102	Loss
CMGC_MAPK_ERK1_MAPK1_ST	P04637	TP53	P28482	MAPK1	T150	P152A	152	Missense	proximal	2	no	11.263	11.134	EPSD	COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P04637	TP53	P28482	MAPK1	T150	P152T	152	Missense	proximal	2	no	11.263	11.213	EPSD	COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P04637	TP53	P28482	MAPK1	T150	P152H	152	Missense	proximal	2	no	11.263	11.133	EPSD	COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P04637	TP53	P28482	MAPK1	T150	P153T	153	Missense	distal	3	no	11.263	11.325	EPSD	COSMIC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P04637	TP53	P28482	MAPK1	T150	V147I	147	Missense	distal	-3	no	11.263	11.129	EPSD	COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P04637	TP53	P28482	MAPK1	T150	P153L	153	Missense	distal	3	no	11.263	11.353	EPSD	COSMIC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P04637	TP53	P28482	MAPK1	T150	V147D	147	Missense	distal	-3	no	11.263	11.442	EPSD	COSMIC;GDSC;CCLE	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P04637	TP53	P28482	MAPK1	T150	S149P	149	Missense	proximal	-1	no	11.263	11.307	EPSD	COSMIC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P04637	TP53	P28482	MAPK1	T150	P152K	152	Missense	proximal	2	no	11.263	11.196	EPSD	COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P04637	TP53	P28482	MAPK1	T150	P153S	153	Missense	distal	3	no	11.263	11.332	EPSD	COSMIC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P04637	TP53	P28482	MAPK1	T150	G154C	154	Missense	distal	4	no	11.263	11.031	EPSD	COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P04637	TP53	P28482	MAPK1	T150	S149F	149	Missense	proximal	-1	no	11.263	11.217	EPSD	COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P04637	TP53	P28482	MAPK1	T150	G154D	154	Missense	distal	4	no	11.263	11.216	EPSD	COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P04637	TP53	P28482	MAPK1	T150	V157I	157	Missense	distal	7	no	11.263	11.528	EPSD	COSMIC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P04637	TP53	P28482	MAPK1	T150	W146R	146	Missense	distal	-4	no	11.263	12.206	EPSD	COSMIC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P04637	TP53	P28482	MAPK1	T150	Q144R	144	Missense	distal	-6	no	11.263	11.287	EPSD	COSMIC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P04637	TP53	P28482	MAPK1	T150	D148V	148	Missense	proximal	-2	no	11.263	12.692	EPSD	COSMIC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P04637	TP53	P28482	MAPK1	T150	S149Y	149	Missense	proximal	-1	no	11.263	11.231	EPSD	COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P04637	TP53	P28482	MAPK1	T150	T150I	150	Missense	central	0	yes	11.263	0.000	EPSD	COSMIC	8.102	Loss
CMGC_MAPK_ERK1_MAPK1_ST	P04637	TP53	P28482	MAPK1	T150	S149T	149	Missense	proximal	-1	no	11.263	11.264	EPSD	COSMIC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P04637	TP53	P28482	MAPK1	T150	W146G	146	Missense	distal	-4	no	11.263	11.945	EPSD	COSMIC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P04637	TP53	P28482	MAPK1	T150	L145M	145	Missense	distal	-5	no	11.263	11.267	EPSD	COSMIC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P04637	TP53	P28482	MAPK1	T150	V143L	143	Missense	distal	-7	no	11.263	11.270	EPSD	COSMIC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P04637	TP53	P28482	MAPK1	T150	R156S	156	Missense	distal	6	no	11.263	11.370	EPSD	COSMIC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P04637	TP53	P28482	MAPK1	T150	D148E	148	Missense	proximal	-2	no	11.263	12.185	EPSD	COSMIC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P04637	TP53	P28482	MAPK1	T150	V147F	147	Missense	distal	-3	no	11.263	11.161	EPSD	COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P04637	TP53	P28482	MAPK1	T150	T155A	155	Missense	distal	5	no	11.263	11.177	EPSD	COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P04637	TP53	P28482	MAPK1	T150	V147E	147	Missense	distal	-3	no	11.263	11.391	EPSD	COSMIC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P04637	TP53	P28482	MAPK1	T150	G154I	154	Missense	distal	4	no	11.263	11.146	EPSD	COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P04637	TP53	P28482	MAPK1	T150	D148G	148	Missense	proximal	-2	no	11.263	11.371	EPSD	COSMIC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P04637	TP53	P28482	MAPK1	T150	Q144K	144	Missense	distal	-6	no	11.263	11.264	EPSD	COSMIC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P04637	TP53	P28482	MAPK1	T150	V147A	147	Missense	distal	-3	no	11.263	11.203	EPSD	COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P04637	TP53	P28482	MAPK1	T150	L145V	145	Missense	distal	-5	no	11.263	11.210	EPSD	COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P04637	TP53	P28482	MAPK1	T150	T150K	150	Missense	central	0	yes	11.263	0.000	EPSD	COSMIC	8.102	Loss
CMGC_MAPK_ERK1_MAPK1_ST	P04637	TP53	P28482	MAPK1	T150	P153H	153	Missense	distal	3	no	11.263	11.352	EPSD	COSMIC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P04637	TP53	P28482	MAPK1	T150	V157E	157	Missense	distal	7	no	11.263	10.921	EPSD	COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P04637	TP53	P28482	MAPK1	T150	T155S	155	Missense	distal	5	no	11.263	11.337	EPSD	COSMIC;CCLE	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P04637	TP53	P28482	MAPK1	T150	D148H	148	Missense	proximal	-2	no	11.263	11.810	EPSD	COSMIC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P04637	TP53	P28482	MAPK1	T150	P153A	153	Missense	distal	3	no	11.263	11.341	EPSD	COSMIC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P04637	TP53	P28482	MAPK1	T150	T150R	150	Missense	central	0	yes	11.263	0.000	EPSD	COSMIC	8.102	Loss
CMGC_MAPK_ERK1_MAPK1_ST	P04637	TP53	P28482	MAPK1	T150	T155L	155	Missense	distal	5	no	11.263	11.106	EPSD	COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P04637	TP53	P28482	MAPK1	T150	G154A	154	Missense	distal	4	no	11.263	11.219	EPSD	COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P04637	TP53	P28482	MAPK1	T150	T150A	150	Missense	central	0	yes	11.263	0.000	EPSD	COSMIC	8.102	Loss
CMGC_MAPK_ERK1_MAPK1_ST	P04637	TP53	P28482	MAPK1	T150	W146C	146	Missense	distal	-4	no	11.263	11.568	EPSD	COSMIC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P04637	TP53	P28482	MAPK1	T150	P153F	153	Missense	distal	3	no	11.263	11.395	EPSD	COSMIC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P04637	TP53	P28482	MAPK1	T150	D148Y	148	Missense	proximal	-2	no	11.263	12.448	EPSD	COSMIC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P04637	TP53	P28482	MAPK1	T150	G154R	154	Missense	distal	4	no	11.263	11.290	EPSD	COSMIC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P04637	TP53	P28482	MAPK1	T211	R209P	209	Missense	proximal	-2	no	7.550	9.369	EPSD	COSMIC	8.102	Gain
CMGC_MAPK_ERK1_MAPK1_ST	P04637	TP53	P28482	MAPK1	S313	S314F	314	Missense	proximal	1	no	5.390	8.215	EPSD	COSMIC	8.102	Gain
CMGC_MAPK_ERK1_MAPK1_ST	P04637	TP53	P28482	MAPK1	S314	S315P	315	Missense	proximal	1	no	4.539	13.934	EPSD	COSMIC	8.102	Gain
CMGC_MAPK_ERK1_MAPK1_ST	P04637	TP53	P28482	MAPK1	S315	N310T	310	Missense	distal	-5	no	13.607	13.684	EPSD	COSMIC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P04637	TP53	P28482	MAPK1	S315	Q317R	317	Missense	proximal	2	no	13.607	13.899	EPSD	COSMIC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P04637	TP53	P28482	MAPK1	S315	P309S	309	Missense	distal	-6	no	13.607	13.581	EPSD	COSMIC;GDSC;CCLE	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P04637	TP53	P28482	MAPK1	S315	K319E	319	Missense	distal	4	no	13.607	13.593	EPSD	COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P04637	TP53	P28482	MAPK1	S315	P322L	322	Missense	distal	7	no	13.607	13.907	EPSD	COSMIC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P04637	TP53	P28482	MAPK1	S315	K320N	320	Missense	distal	5	no	13.607	13.638	EPSD	COSMIC;GDSC;CCLE	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P04637	TP53	P28482	MAPK1	S315	N310L	310	Missense	distal	-5	no	13.607	13.730	EPSD	COSMIC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P04637	TP53	P28482	MAPK1	S315	T312S	312	Missense	distal	-3	no	13.607	13.640	EPSD	COSMIC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P04637	TP53	P28482	MAPK1	S315	N311Y	311	Missense	distal	-4	no	13.607	12.977	EPSD	COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P04637	TP53	P28482	MAPK1	S315	P322R	322	Missense	distal	7	no	13.607	13.622	EPSD	COSMIC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P04637	TP53	P28482	MAPK1	S315	N311K	311	Missense	distal	-4	no	13.607	13.639	EPSD	COSMIC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P04637	TP53	P28482	MAPK1	S315	Q317K	317	Missense	proximal	2	no	13.607	13.718	EPSD	COSMIC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P04637	TP53	P28482	MAPK1	S315	S315P	315	Missense	central	0	yes	13.607	0.000	EPSD	COSMIC	8.102	Loss
CMGC_MAPK_ERK1_MAPK1_ST	P04637	TP53	P28482	MAPK1	S315	N310H	310	Missense	distal	-5	no	13.607	13.706	EPSD	COSMIC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P04637	TP53	P28482	MAPK1	S315	S314C	314	Missense	proximal	-1	no	13.607	13.529	EPSD	COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P04637	TP53	P28482	MAPK1	S315	P318A	318	Missense	distal	3	no	13.607	13.685	EPSD	COSMIC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P04637	TP53	P28482	MAPK1	S315	P316L	316	Missense	proximal	1	no	13.607	4.798	EPSD	COSMIC	8.102	Loss
CMGC_MAPK_ERK1_MAPK1_ST	P04637	TP53	P28482	MAPK1	S315	L308M	308	Missense	distal	-7	no	13.607	13.598	EPSD	COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P04637	TP53	P28482	MAPK1	S315	S313C	313	Missense	proximal	-2	no	13.607	12.675	EPSD	COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P04637	TP53	P28482	MAPK1	S315	N311H	311	Missense	distal	-4	no	13.607	13.408	EPSD	COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P04637	TP53	P28482	MAPK1	S315	L308V	308	Missense	distal	-7	no	13.607	13.601	EPSD	COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P04637	TP53	P28482	MAPK1	S315	S314F	314	Missense	proximal	-1	no	13.607	13.561	EPSD	COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P04637	TP53	P28482	MAPK1	S315	K319R	319	Missense	distal	4	no	13.607	13.597	EPSD	COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P04637	TP53	P28482	MAPK1	S315	T312A	312	Missense	distal	-3	no	13.607	13.450	EPSD	COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P04637	TP53	P28482	MAPK1	S315	N310D	310	Missense	distal	-5	no	13.607	13.652	EPSD	COSMIC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P04637	TP53	P28482	MAPK1	S315	N311D	311	Missense	distal	-4	no	13.607	13.635	EPSD	COSMIC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P04637	TP53	P28482	MAPK1	S315	P309R	309	Missense	distal	-6	no	13.607	13.615	EPSD	COSMIC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P04637	TP53	P28482	MAPK1	S315	S313N	313	Missense	proximal	-2	no	13.607	13.622	EPSD	COSMIC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P04637	TP53	P28482	MAPK1	S315	Q317P	317	Missense	proximal	2	no	13.607	13.785	EPSD	COSMIC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P04637	TP53	P28482	MAPK1	S315	P316S	316	Missense	proximal	1	no	13.607	4.212	EPSD	COSMIC	8.102	Loss
CMGC_MAPK_ERK1_MAPK1_ST	P04637	TP53	P28482	MAPK1	S366	S367F	367	Missense	proximal	1	no	7.468	10.294	EPSD	COSMIC	8.102	Gain
CMGC_MAPK_ERK1_MAPK1_ST	P04637	TP53	P28482	MAPK1	S376	K370N	370	Missense	distal	-6	no	8.969	8.962	EPSD	COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P04637	TP53	P28482	MAPK1	S376	L383F	383	Missense	distal	7	no	8.969	9.028	EPSD	COSMIC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P04637	TP53	P28482	MAPK1	S376	R379H	379	Missense	distal	3	no	8.969	9.012	EPSD	COSMIC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P04637	TP53	P28482	MAPK1	S376	H380Y	380	Missense	distal	4	no	8.969	8.939	EPSD	COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P04637	TP53	P28482	MAPK1	S376	T377I	377	Missense	proximal	1	no	8.969	7.650	EPSD	COSMIC	8.102	Loss
CMGC_MAPK_ERK1_MAPK1_ST	P04637	TP53	P28482	MAPK1	S376	S378F	378	Missense	proximal	2	no	8.969	8.838	EPSD	COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P04637	TP53	P28482	MAPK1	S376	K381N	381	Missense	distal	5	no	8.969	9.000	EPSD	COSMIC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P04637	TP53	P28482	MAPK1	S376	R379P	379	Missense	distal	3	no	8.969	8.923	EPSD	COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P04637	TP53	P28482	MAPK1	S376	K373R	373	Missense	distal	-3	no	8.969	9.207	EPSD	COSMIC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P04637	TP53	P28482	MAPK1	S376	S376F	376	Missense	central	0	yes	8.969	0.000	EPSD	COSMIC	8.102	Loss
CMGC_MAPK_ERK1_MAPK1_ST	P04637	TP53	P28482	MAPK1	S376	G374S	374	Missense	proximal	-2	no	8.969	9.329	EPSD	COSMIC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P04637	TP53	P28482	MAPK1	S376	S376A	376	Missense	central	0	yes	8.969	0.000	EPSD	COSMIC	8.102	Loss
CMGC_MAPK_ERK1_MAPK1_ST	P04637	TP53	P28482	MAPK1	S376	S371P	371	Missense	distal	-5	no	8.969	8.895	EPSD	COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P04637	TP53	P28482	MAPK1	T377	S378F	378	Missense	proximal	1	no	5.789	8.615	EPSD	COSMIC	8.102	Gain
CMGC_MAPK_ERK1_MAPK1_ST	P04637	TP53	P28482	MAPK1	S378	R379P	379	Missense	proximal	1	no	5.734	15.389	EPSD	COSMIC	8.102	Gain
CMGC_MAPK_ERK1_MAPK1_ST	P04637	TP53	P28482	MAPK1	S392	P390L	390	Missense	proximal	-2	no	8.624	6.707	EPSD	COSMIC	8.102	Loss
CMGC_MAPK_ERK1_MAPK1_ST	P04637	TP53	P28482	MAPK1	S392	S392P	392	Missense	central	0	yes	8.624	0.000	EPSD	COSMIC	8.102	Loss
CMGC_MAPK_ERK1_MAPK1_ST	P04637	TP53	P28482	MAPK1	S392	K386N	386	Missense	distal	-6	no	8.624	8.616	EPSD	COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P04637	TP53	P28482	MAPK1	S392	G389E	389	Missense	distal	-3	no	8.624	8.633	EPSD	COSMIC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P04637	TP53	P28482	MAPK1	S392	S392L	392	Missense	central	0	yes	8.624	0.000	EPSD	COSMIC	8.102	Loss
CMGC_MAPK_ERK1_MAPK1_ST	P04637	TP53	P28482	MAPK1	S392	D391N	391	Missense	proximal	-1	no	8.624	8.685	EPSD	COSMIC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P04637	TP53	P28482	MAPK1	S392	D391Y	391	Missense	proximal	-1	no	8.624	8.604	EPSD	COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P04637	TP53	P28482	MAPK1	S392	G389V	389	Missense	distal	-3	no	8.624	8.505	EPSD	COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q7L5N1	COPS6	P28482	MAPK1	S60	Q61P	61	Missense	proximal	1	no	3.651	12.144	EPSD	COSMIC	8.102	Gain
CMGC_MAPK_ERK1_MAPK1_ST	Q14686	NCOA6	P28482	MAPK1	T416	S412F	412	Missense	distal	-4	no	14.203	13.942	EPSD	COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q14686	NCOA6	P28482	MAPK1	T416	G409E	409	Missense	distal	-7	no	14.203	14.226	EPSD	COSMIC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q14686	NCOA6	P28482	MAPK1	S667	P666R	666	Missense	proximal	-1	no	9.041	9.022	EPSD	COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q14686	NCOA6	P28482	MAPK1	S673	P666R	666	Missense	distal	-7	no	13.034	13.029	EPSD	COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q14686	NCOA6	P28482	MAPK1	S1091	V1088M	1088	Missense	distal	-3	no	16.186	16.056	EPSD	COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q14686	NCOA6	P28482	MAPK1	S1091	A1086S	1086	Missense	distal	-5	no	16.186	16.135	EPSD	COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q14686	NCOA6	P28482	MAPK1	T1211	S1207P	1207	Missense	distal	-4	no	15.809	15.893	EPSD	COSMIC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q14686	NCOA6	P28482	MAPK1	S1216	P1219L	1219	Missense	distal	3	no	14.689	14.779	EPSD	COSMIC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q14686	NCOA6	P28482	MAPK1	T1224	P1229L	1229	Missense	distal	5	no	16.939	16.726	EPSD	COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q14686	NCOA6	P28482	MAPK1	T1224	P1219L	1219	Missense	distal	-5	no	16.939	17.088	EPSD	COSMIC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q14686	NCOA6	P28482	MAPK1	S1240	L1244F	1244	Missense	distal	4	no	15.213	15.145	EPSD	COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q14686	NCOA6	P28482	MAPK1	S1240	R1243K	1243	Missense	distal	3	no	15.213	15.164	EPSD	COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q14686	NCOA6	P28482	MAPK1	S1240	P1234S	1234	Missense	distal	-6	no	15.213	15.187	EPSD	COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q14686	NCOA6	P28482	MAPK1	T1299	P1294L	1294	Missense	distal	-5	no	13.686	13.835	EPSD	COSMIC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q14686	NCOA6	P28482	MAPK1	S1325	P1326S	1326	Missense	proximal	1	no	14.502	5.107	EPSD	COSMIC	8.102	Loss
CMGC_MAPK_ERK1_MAPK1_ST	Q14686	NCOA6	P28482	MAPK1	S1325	S1327I	1327	Missense	proximal	2	no	14.502	14.359	EPSD	COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q14686	NCOA6	P28482	MAPK1	S1325	R1331S	1331	Missense	distal	6	no	14.502	14.609	EPSD	COSMIC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q14686	NCOA6	P28482	MAPK1	S1343	S1349A	1349	Missense	distal	6	no	14.459	14.162	EPSD	COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q14686	NCOA6	P28482	MAPK1	S1343	K1350N	1350	Missense	distal	7	no	14.459	14.493	EPSD	COSMIC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q14686	NCOA6	P28482	MAPK1	S1481	E1474K	1474	Missense	distal	-7	no	15.799	15.792	EPSD	COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q14686	NCOA6	P28482	MAPK1	S1481	E1486K	1486	Missense	distal	5	no	15.799	15.739	EPSD	COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q14686	NCOA6	P28482	MAPK1	S1481	A1487S	1487	Missense	distal	6	no	15.799	16.095	EPSD	COSMIC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q14686	NCOA6	P28482	MAPK1	S1481	M1484I	1484	Missense	distal	3	no	15.799	15.842	EPSD	COSMIC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q14686	NCOA6	P28482	MAPK1	S1721	P1724L	1724	Missense	distal	3	no	12.747	12.837	EPSD	COSMIC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q14686	NCOA6	P28482	MAPK1	S1721	P1724S	1724	Missense	distal	3	no	12.747	12.816	EPSD	COSMIC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q14686	NCOA6	P28482	MAPK1	S1721	P1722T	1722	Missense	proximal	1	no	12.747	4.248	EPSD	COSMIC	8.102	Loss
CMGC_MAPK_ERK1_MAPK1_ST	Q14686	NCOA6	P28482	MAPK1	S1721	A1717V	1717	Missense	distal	-4	no	12.747	12.686	EPSD	COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q14686	NCOA6	P28482	MAPK1	S1721	S1719F	1719	Missense	proximal	-2	no	12.747	12.941	EPSD	COSMIC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q14686	NCOA6	P28482	MAPK1	S1721	P1714L	1714	Missense	distal	-7	no	12.747	12.735	EPSD	COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q14686	NCOA6	P28482	MAPK1	T1739	L1732M	1732	Missense	distal	-7	no	14.570	14.561	EPSD	COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q14686	NCOA6	P28482	MAPK1	S1751	P1758L	1758	Missense	distal	7	no	13.564	13.863	EPSD	COSMIC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q14686	NCOA6	P28482	MAPK1	S1756	P1758L	1758	Missense	proximal	2	no	8.234	8.087	EPSD	COSMIC	8.102	Loss
CMGC_MAPK_ERK1_MAPK1_ST	Q14686	NCOA6	P28482	MAPK1	S1800	S1803P	1803	Missense	distal	3	no	12.806	12.737	EPSD	COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q14686	NCOA6	P28482	MAPK1	S1809	S1803P	1803	Missense	distal	-6	no	14.569	14.595	EPSD	COSMIC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q14686	NCOA6	P28482	MAPK1	S1809	K1815N	1815	Missense	distal	6	no	14.569	14.416	EPSD	COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q14686	NCOA6	P28482	MAPK1	S1809	S1809I	1809	Missense	central	0	yes	14.569	0.000	EPSD	COSMIC	8.102	Loss
CMGC_MAPK_ERK1_MAPK1_ST	Q14686	NCOA6	P28482	MAPK1	S1892	P1896Q	1896	Missense	distal	4	no	14.453	14.345	EPSD	COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q14686	NCOA6	P28482	MAPK1	S1892	K1888Q	1888	Missense	distal	-4	no	14.453	14.271	EPSD	COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q14686	NCOA6	P28482	MAPK1	T1898	P1896Q	1896	Missense	proximal	-2	no	9.197	6.203	EPSD	COSMIC	8.102	Loss
CMGC_MAPK_ERK1_MAPK1_ST	Q14686	NCOA6	P28482	MAPK1	S2043	S2039F	2039	Missense	distal	-4	no	10.590	10.329	EPSD	COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q14686	NCOA6	P28482	MAPK1	S2053	R2059Q	2059	Missense	distal	6	no	9.859	9.679	EPSD	COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q9UQC2	GAB2	P28482	MAPK1	S133	D126E	126	Missense	distal	-7	no	8.655	8.663	EPSD	COSMIC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q9UQC2	GAB2	P28482	MAPK1	S133	R129S	129	Missense	distal	-4	no	8.655	8.661	EPSD	COSMIC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q9UQC2	GAB2	P28482	MAPK1	S133	P138R	138	Missense	distal	5	no	8.655	8.705	EPSD	COSMIC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q9UQC2	GAB2	P28482	MAPK1	S133	V131I	131	Missense	proximal	-2	no	8.655	8.633	EPSD	COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q9UQC2	GAB2	P28482	MAPK1	S141	P138R	138	Missense	distal	-3	no	14.587	14.567	EPSD	COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q9UQC2	GAB2	P28482	MAPK1	T171	S164F	164	Missense	distal	-7	no	9.851	9.831	EPSD	COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q9UQC2	GAB2	P28482	MAPK1	T171	P174S	174	Missense	distal	3	no	9.851	9.920	EPSD	COSMIC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q9UQC2	GAB2	P28482	MAPK1	T171	P167S	167	Missense	distal	-4	no	9.851	9.767	EPSD	COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q9UQC2	GAB2	P28482	MAPK1	S274	S281N	281	Missense	distal	7	no	8.480	8.463	EPSD	COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q9UQC2	GAB2	P28482	MAPK1	S274	H277Y	277	Missense	distal	3	no	8.480	8.519	EPSD	COSMIC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q9UQC2	GAB2	P28482	MAPK1	S274	K279N	279	Missense	distal	5	no	8.480	8.511	EPSD	COSMIC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q9UQC2	GAB2	P28482	MAPK1	S274	P269S	269	Missense	distal	-5	no	8.480	8.555	EPSD	COSMIC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q9UQC2	GAB2	P28482	MAPK1	T294	D288N	288	Missense	distal	-6	no	9.420	9.375	EPSD	COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q9UQC2	GAB2	P28482	MAPK1	T294	T297M	297	Missense	distal	3	no	9.420	9.443	EPSD	COSMIC;GDSC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q9UQC2	GAB2	P28482	MAPK1	T294	T287I	287	Missense	distal	-7	no	9.420	9.406	EPSD	COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q9UQC2	GAB2	P28482	MAPK1	T294	T301N	301	Missense	distal	7	no	9.420	9.251	EPSD	COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q9UQC2	GAB2	P28482	MAPK1	T319	M314I	314	Missense	distal	-5	no	16.038	16.094	EPSD	COSMIC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q9UQC2	GAB2	P28482	MAPK1	T319	P317L	317	Missense	proximal	-2	no	16.038	14.120	EPSD	COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q9UQC2	GAB2	P28482	MAPK1	T319	A318T	318	Missense	proximal	-1	no	16.038	16.032	EPSD	COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q9UQC2	GAB2	P28482	MAPK1	S322	P317L	317	Missense	distal	-5	no	11.436	11.585	EPSD	COSMIC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q9UQC2	GAB2	P28482	MAPK1	S322	A318T	318	Missense	distal	-4	no	11.436	11.416	EPSD	COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q9UQC2	GAB2	P28482	MAPK1	S368	Q370R	370	Missense	proximal	2	no	15.866	16.157	EPSD	COSMIC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q9UQC2	GAB2	P28482	MAPK1	S368	G367D	367	Missense	proximal	-1	no	15.866	15.865	EPSD	COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q9UQC2	GAB2	P28482	MAPK1	T391	L392P	392	Missense	proximal	1	no	7.069	15.878	EPSD	COSMIC	8.102	Gain
CMGC_MAPK_ERK1_MAPK1_ST	Q9UQC2	GAB2	P28482	MAPK1	S480	D487N	487	Missense	distal	7	no	18.893	18.880	EPSD	COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q9UQC2	GAB2	P28482	MAPK1	S480	H484N	484	Missense	distal	4	no	18.893	19.020	EPSD	COSMIC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q9UQC2	GAB2	P28482	MAPK1	S506	S503R	503	Missense	distal	-3	no	8.453	8.609	EPSD	COSMIC;CCLE	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q9UQC2	GAB2	P28482	MAPK1	S506	G505A	505	Missense	proximal	-1	no	8.453	8.470	EPSD	COSMIC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q9UQC2	GAB2	P28482	MAPK1	S506	R500L	500	Missense	distal	-6	no	8.453	8.353	EPSD	COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q9UQC2	GAB2	P28482	MAPK1	S506	P511H	511	Missense	distal	5	no	8.453	8.326	EPSD	COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q9UQC2	GAB2	P28482	MAPK1	S506	G505E	505	Missense	proximal	-1	no	8.453	8.492	EPSD	COSMIC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q9UQC2	GAB2	P28482	MAPK1	S543	P544H	544	Missense	proximal	1	no	13.639	5.815	EPSD	COSMIC	8.102	Loss
CMGC_MAPK_ERK1_MAPK1_ST	Q9UQC2	GAB2	P28482	MAPK1	S543	D537G	537	Missense	distal	-6	no	13.639	13.572	EPSD	COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q9UQC2	GAB2	P28482	MAPK1	S543	E538K	538	Missense	distal	-5	no	13.639	13.616	EPSD	COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q9UQC2	GAB2	P28482	MAPK1	S623	Q620P	620	Missense	distal	-3	no	15.505	15.802	PhosphoSitePlus	COSMIC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q9UQC2	GAB2	P28482	MAPK1	S625	S631C	631	Missense	distal	6	no	14.030	13.162	EPSD	COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q9UQC2	GAB2	P28482	MAPK1	S625	Q620P	620	Missense	distal	-5	no	14.030	13.905	EPSD	COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P10828	THRB	P28482	MAPK1	S55	L58F	58	Missense	distal	3	no	14.655	14.697	EPSD	COSMIC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P10828	THRB	P28482	MAPK1	S55	I59L	59	Missense	distal	4	no	14.655	14.712	EPSD	COSMIC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P10828	THRB	P28482	MAPK1	S55	Q53R	53	Missense	proximal	-2	no	14.655	15.830	EPSD	COSMIC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P10828	THRB	P28482	MAPK1	S142	S142F	142	Missense	central	0	yes	8.459	0.000	PhosphoSitePlus	COSMIC	8.102	Loss
CMGC_MAPK_ERK1_MAPK1_ST	P14921	ETS1	P28482	MAPK1	S26	M29V	29	Missense	distal	3	no	15.770	15.743	EPSD	COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P14921	ETS1	P28482	MAPK1	S26	L23F	23	Missense	distal	-3	no	15.770	15.745	EPSD	COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P14921	ETS1	P28482	MAPK1	S26	L23V	23	Missense	distal	-3	no	15.770	15.847	EPSD	COSMIC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P14921	ETS1	P28482	MAPK1	S26	D33G	33	Missense	distal	7	no	15.770	15.843	EPSD	COSMIC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P14921	ETS1	P28482	MAPK1	T38	S40N	40	Missense	proximal	2	no	15.656	15.608	PhosphoSitePlus	COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P14921	ETS1	P28482	MAPK1	T38	M45I	45	Missense	distal	7	no	15.656	15.844	PhosphoSitePlus	COSMIC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P14921	ETS1	P28482	MAPK1	T38	P39S	39	Missense	proximal	1	no	15.656	6.261	PhosphoSitePlus	COSMIC	8.102	Loss
CMGC_MAPK_ERK1_MAPK1_ST	P14921	ETS1	P28482	MAPK1	T38	D33G	33	Missense	distal	-5	no	15.656	15.654	PhosphoSitePlus	COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P14921	ETS1	P28482	MAPK1	T38	P35L	35	Missense	distal	-3	no	15.656	15.272	PhosphoSitePlus	COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P14921	ETS1	P28482	MAPK1	T38	M44I	44	Missense	distal	6	no	15.656	15.422	PhosphoSitePlus	COSMIC;CCLE	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P14921	ETS1	P28482	MAPK1	T232	V231I	231	Missense	proximal	-1	no	11.062	11.022	EPSD	COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P14921	ETS1	P28482	MAPK1	T232	N235S	235	Missense	distal	3	no	11.062	11.140	EPSD	COSMIC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P14921	ETS1	P28482	MAPK1	T232	K227N	227	Missense	distal	-5	no	11.062	11.085	EPSD	COSMIC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P14921	ETS1	P28482	MAPK1	T232	D234Y	234	Missense	proximal	2	no	11.062	10.882	EPSD	COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P14921	ETS1	P28482	MAPK1	T232	V231A	231	Missense	proximal	-1	no	11.062	11.051	EPSD	COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P14921	ETS1	P28482	MAPK1	S276	R279H	279	Missense	distal	3	no	8.087	8.130	EPSD	COSMIC;CCLE	8.102	Gain
CMGC_MAPK_ERK1_MAPK1_ST	P14921	ETS1	P28482	MAPK1	S276	Q278K	278	Missense	proximal	2	no	8.087	8.198	EPSD	COSMIC	8.102	Gain
CMGC_MAPK_ERK1_MAPK1_ST	P14921	ETS1	P28482	MAPK1	S276	R279C	279	Missense	distal	3	no	8.087	8.214	EPSD	COSMIC	8.102	Gain
CMGC_MAPK_ERK1_MAPK1_ST	P14921	ETS1	P28482	MAPK1	S276	F274L	274	Missense	proximal	-2	no	8.087	8.810	EPSD	COSMIC	8.102	Gain
CMGC_MAPK_ERK1_MAPK1_ST	P14921	ETS1	P28482	MAPK1	S282	D287N	287	Missense	distal	5	no	8.112	8.014	EPSD	COSMIC	8.102	Loss
CMGC_MAPK_ERK1_MAPK1_ST	P14921	ETS1	P28482	MAPK1	S282	R279H	279	Missense	distal	-3	no	8.112	7.783	EPSD	COSMIC;CCLE	8.102	Loss
CMGC_MAPK_ERK1_MAPK1_ST	P14921	ETS1	P28482	MAPK1	S282	Q278K	278	Missense	distal	-4	no	8.112	8.294	EPSD	COSMIC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P14921	ETS1	P28482	MAPK1	S282	L277R	277	Missense	distal	-5	no	8.112	8.011	EPSD	COSMIC	8.102	Loss
CMGC_MAPK_ERK1_MAPK1_ST	P14921	ETS1	P28482	MAPK1	S282	R279C	279	Missense	distal	-3	no	8.112	7.429	EPSD	COSMIC	8.102	Loss
CMGC_MAPK_ERK1_MAPK1_ST	P14921	ETS1	P28482	MAPK1	S285	D287N	287	Missense	proximal	2	no	8.754	8.694	EPSD	COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P14921	ETS1	P28482	MAPK1	S285	R279H	279	Missense	distal	-6	no	8.754	8.671	EPSD	COSMIC;CCLE	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P14921	ETS1	P28482	MAPK1	S285	Q278K	278	Missense	distal	-7	no	8.754	8.749	EPSD	COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P14921	ETS1	P28482	MAPK1	S285	R279C	279	Missense	distal	-6	no	8.754	8.579	EPSD	COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q9NRF2	SH2B1	P28482	MAPK1	S25	E31D	31	Missense	distal	6	no	13.882	13.803	EPSD	COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q9NRF2	SH2B1	P28482	MAPK1	S88	A81T	81	Missense	distal	-7	no	13.850	13.836	EPSD	COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q9NRF2	SH2B1	P28482	MAPK1	S88	S84N	84	Missense	distal	-4	no	13.850	13.892	EPSD	COSMIC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q9NRF2	SH2B1	P28482	MAPK1	S96	P103T	103	Missense	distal	7	no	15.960	16.123	PhosphoSitePlus	COSMIC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q9NRF2	SH2B1	P28482	MAPK1	S102	L108V	108	Missense	distal	6	no	13.059	13.251	EPSD	COSMIC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q9NRF2	SH2B1	P28482	MAPK1	S102	P103T	103	Missense	proximal	1	no	13.059	4.561	EPSD	COSMIC	8.102	Loss
CMGC_MAPK_ERK1_MAPK1_ST	Q9NRF2	SH2B1	P28482	MAPK1	S102	E109Q	109	Missense	distal	7	no	13.059	13.237	EPSD	COSMIC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q9NRF2	SH2B1	P28482	MAPK1	S136	S139F	139	Missense	distal	3	no	9.648	9.710	EPSD	COSMIC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q9NRF2	SH2B1	P28482	MAPK1	S136	G131V	131	Missense	distal	-5	no	9.648	9.676	EPSD	COSMIC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q9NRF2	SH2B1	P28482	MAPK1	S136	P134T	134	Missense	proximal	-2	no	9.648	6.948	EPSD	COSMIC	8.102	Loss
CMGC_MAPK_ERK1_MAPK1_ST	Q9NRF2	SH2B1	P28482	MAPK1	S136	G131S	131	Missense	distal	-5	no	9.648	9.654	EPSD	COSMIC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q9NRF2	SH2B1	P28482	MAPK1	S139	S139F	139	Missense	central	0	yes	8.285	0.000	EPSD	COSMIC	8.102	Loss
CMGC_MAPK_ERK1_MAPK1_ST	Q9NRF2	SH2B1	P28482	MAPK1	S139	K146R	146	Missense	distal	7	no	8.285	8.340	EPSD	COSMIC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q9NRF2	SH2B1	P28482	MAPK1	S139	P134T	134	Missense	distal	-5	no	8.285	8.388	EPSD	COSMIC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q9NRF2	SH2B1	P28482	MAPK1	S219	D216G	216	Missense	distal	-3	no	12.112	12.052	EPSD	COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q9NRF2	SH2B1	P28482	MAPK1	S219	P220S	220	Missense	proximal	1	no	12.112	2.717	EPSD	COSMIC	8.102	Loss
CMGC_MAPK_ERK1_MAPK1_ST	Q9NRF2	SH2B1	P28482	MAPK1	S376	C380R	380	Missense	distal	4	no	10.657	10.916	EPSD	COSMIC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q9NRF2	SH2B1	P28482	MAPK1	S376	P377L	377	Missense	proximal	1	no	10.657	1.848	EPSD	COSMIC	8.102	Loss
CMGC_MAPK_ERK1_MAPK1_ST	Q9NRF2	SH2B1	P28482	MAPK1	S384	C380R	380	Missense	distal	-4	no	12.580	13.218	EPSD	COSMIC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q9NRF2	SH2B1	P28482	MAPK1	S384	P377L	377	Missense	distal	-7	no	12.580	12.568	EPSD	COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q9NRF2	SH2B1	P28482	MAPK1	T396	R401S	401	Missense	distal	5	no	8.361	8.330	EPSD	COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P53355	DAPK1	P28482	MAPK1	T180	P186L	186	Missense	distal	6	no	11.610	11.203	EPSD	COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P53355	DAPK1	P28482	MAPK1	T612	R611Q	611	Missense	proximal	-1	no	13.055	13.034	EPSD	COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P53355	DAPK1	P28482	MAPK1	T612	L616F	616	Missense	distal	4	no	13.055	12.987	EPSD	COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P53355	DAPK1	P28482	MAPK1	S734	R730K	730	Missense	distal	-4	no	19.425	19.503	PhosphoSitePlus	COSMIC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P53355	DAPK1	P28482	MAPK1	S734	P733L	733	Missense	proximal	-1	no	19.425	19.365	PhosphoSitePlus	COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P53355	DAPK1	P28482	MAPK1	T1053	K1047T	1047	Missense	distal	-6	no	13.831	13.797	EPSD	COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P53355	DAPK1	P28482	MAPK1	T1053	H1059R	1059	Missense	distal	6	no	13.831	14.030	EPSD	COSMIC;GDSC;CCLE	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P53355	DAPK1	P28482	MAPK1	T1053	A1056V	1056	Missense	distal	3	no	13.831	13.811	EPSD	COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P41182	BCL6	P28482	MAPK1	S3	A5T	5	Missense	proximal	2	no	11.451	11.530	EPSD	COSMIC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P41182	BCL6	P28482	MAPK1	S3	S3L	3	Missense	central	0	yes	11.451	0.000	EPSD	COSMIC	8.102	Loss
CMGC_MAPK_ERK1_MAPK1_ST	P41182	BCL6	P28482	MAPK1	S3	Q10R	10	Missense	distal	7	no	11.451	11.336	EPSD	COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P41182	BCL6	P28482	MAPK1	S3	P4L	4	Missense	proximal	1	no	11.451	2.641	EPSD	COSMIC	8.102	Loss
CMGC_MAPK_ERK1_MAPK1_ST	P41182	BCL6	P28482	MAPK1	S250	S250Y	250	Missense	central	0	yes	15.929	0.000	EPSD	COSMIC	8.102	Loss
CMGC_MAPK_ERK1_MAPK1_ST	P41182	BCL6	P28482	MAPK1	S250	P245L	245	Missense	distal	-5	no	15.929	16.078	EPSD	COSMIC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P41182	BCL6	P28482	MAPK1	S250	N252H	252	Missense	proximal	2	no	15.929	15.875	EPSD	COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P41182	BCL6	P28482	MAPK1	S250	C254Y	254	Missense	distal	4	no	15.929	16.016	EPSD	COSMIC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P41182	BCL6	P28482	MAPK1	S260	E263K	263	Missense	distal	3	no	15.090	15.097	EPSD	COSMIC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P41182	BCL6	P28482	MAPK1	S260	P261S	261	Missense	proximal	1	no	15.090	5.695	EPSD	COSMIC	8.102	Loss
CMGC_MAPK_ERK1_MAPK1_ST	P41182	BCL6	P28482	MAPK1	S260	E267K	267	Missense	distal	7	no	15.090	15.097	EPSD	COSMIC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P41182	BCL6	P28482	MAPK1	S260	S260L	260	Missense	central	0	yes	15.090	0.000	EPSD	COSMIC	8.102	Loss
CMGC_MAPK_ERK1_MAPK1_ST	P41182	BCL6	P28482	MAPK1	S260	C254Y	254	Missense	distal	-6	no	15.090	15.116	EPSD	COSMIC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P41182	BCL6	P28482	MAPK1	S260	P261L	261	Missense	proximal	1	no	15.090	6.280	EPSD	COSMIC	8.102	Loss
CMGC_MAPK_ERK1_MAPK1_ST	P41182	BCL6	P28482	MAPK1	S330	G327C	327	Missense	distal	-3	no	14.464	13.950	EPSD	COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P41182	BCL6	P28482	MAPK1	S330	V329A	329	Missense	proximal	-1	no	14.464	14.454	EPSD	COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P41182	BCL6	P28482	MAPK1	S330	S330C	330	Missense	central	0	yes	14.464	0.000	EPSD	COSMIC	8.102	Loss
CMGC_MAPK_ERK1_MAPK1_ST	P41182	BCL6	P28482	MAPK1	S330	G327S	327	Missense	distal	-3	no	14.464	14.477	EPSD	COSMIC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P41182	BCL6	P28482	MAPK1	S333	G327C	327	Missense	distal	-6	no	17.066	16.942	PhosphoSitePlus;EPSD	COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P41182	BCL6	P28482	MAPK1	S333	V329A	329	Missense	distal	-4	no	17.066	17.127	PhosphoSitePlus;EPSD	COSMIC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P41182	BCL6	P28482	MAPK1	S333	S330C	330	Missense	distal	-3	no	17.066	16.539	PhosphoSitePlus;EPSD	COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P41182	BCL6	P28482	MAPK1	S333	G327S	327	Missense	distal	-6	no	17.066	17.083	PhosphoSitePlus;EPSD	COSMIC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P41182	BCL6	P28482	MAPK1	S333	D338G	338	Missense	distal	5	no	17.066	17.022	PhosphoSitePlus;EPSD	COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P41182	BCL6	P28482	MAPK1	S343	P344A	344	Missense	proximal	1	no	17.275	9.645	EPSD;PhosphoSitePlus	COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P41182	BCL6	P28482	MAPK1	S343	S349G	349	Missense	distal	6	no	17.275	17.198	EPSD;PhosphoSitePlus	COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P41182	BCL6	P28482	MAPK1	S343	D338G	338	Missense	distal	-5	no	17.275	17.273	EPSD;PhosphoSitePlus	COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P41182	BCL6	P28482	MAPK1	S361	S361F	361	Missense	central	0	yes	13.020	0.000	EPSD	COSMIC	8.102	Loss
CMGC_MAPK_ERK1_MAPK1_ST	P41182	BCL6	P28482	MAPK1	S361	L356F	356	Missense	distal	-5	no	13.020	13.033	EPSD	COSMIC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P41182	BCL6	P28482	MAPK1	S361	C354Y	354	Missense	distal	-7	no	13.020	13.021	EPSD	COSMIC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P41182	BCL6	P28482	MAPK1	S361	P367H	367	Missense	distal	6	no	13.020	12.714	EPSD	COSMIC;GDSC;CCLE	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P41182	BCL6	P28482	MAPK1	S361	P363S	363	Missense	proximal	2	no	13.020	12.992	EPSD	COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P41182	BCL6	P28482	MAPK1	S361	P363L	363	Missense	proximal	2	no	13.020	12.872	EPSD	COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P41182	BCL6	P28482	MAPK1	S361	S359F	359	Missense	proximal	-2	no	13.020	13.213	EPSD	COSMIC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P41182	BCL6	P28482	MAPK1	S361	P362S	362	Missense	proximal	1	no	13.020	3.625	EPSD	COSMIC	8.102	Loss
CMGC_MAPK_ERK1_MAPK1_ST	P41182	BCL6	P28482	MAPK1	S361	Q357H	357	Missense	distal	-4	no	13.020	12.971	EPSD	COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P41182	BCL6	P28482	MAPK1	S361	A364S	364	Missense	distal	3	no	13.020	13.011	EPSD	COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P41182	BCL6	P28482	MAPK1	S366	S361F	361	Missense	distal	-5	no	13.294	13.382	EPSD	COSMIC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P41182	BCL6	P28482	MAPK1	S366	P367H	367	Missense	proximal	1	no	13.294	5.470	EPSD	COSMIC;GDSC;CCLE	8.102	Loss
CMGC_MAPK_ERK1_MAPK1_ST	P41182	BCL6	P28482	MAPK1	S366	P363S	363	Missense	distal	-3	no	13.294	13.117	EPSD	COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P41182	BCL6	P28482	MAPK1	S366	P363L	363	Missense	distal	-3	no	13.294	12.910	EPSD	COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P41182	BCL6	P28482	MAPK1	S366	D369Y	369	Missense	distal	3	no	13.294	13.334	EPSD	COSMIC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P41182	BCL6	P28482	MAPK1	S366	S359F	359	Missense	distal	-7	no	13.294	13.273	EPSD	COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P41182	BCL6	P28482	MAPK1	S366	P362S	362	Missense	distal	-4	no	13.294	13.210	EPSD	COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P41182	BCL6	P28482	MAPK1	S366	A364S	364	Missense	proximal	-2	no	13.294	13.606	EPSD	COSMIC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P41182	BCL6	P28482	MAPK1	S404	A410T	410	Missense	distal	6	no	13.330	13.416	EPSD	COSMIC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P41182	BCL6	P28482	MAPK1	S404	R402C	402	Missense	proximal	-2	no	13.330	11.382	EPSD	COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P41182	BCL6	P28482	MAPK1	S427	S434N	434	Missense	distal	7	no	13.658	13.640	EPSD	COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P41182	BCL6	P28482	MAPK1	S457	T455M	455	Missense	proximal	-2	no	13.867	12.552	EPSD	COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P41182	BCL6	P28482	MAPK1	S457	P458S	458	Missense	proximal	1	no	13.867	4.472	EPSD	COSMIC;GDSC;CCLE	8.102	Loss
CMGC_MAPK_ERK1_MAPK1_ST	P41182	BCL6	P28482	MAPK1	S457	V450I	450	Missense	distal	-7	no	13.867	13.854	EPSD	COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P41182	BCL6	P28482	MAPK1	S457	G456V	456	Missense	proximal	-1	no	13.867	13.895	EPSD	COSMIC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P41182	BCL6	P28482	MAPK1	S457	M454V	454	Missense	distal	-3	no	13.867	13.997	EPSD	COSMIC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P41182	BCL6	P28482	MAPK1	S457	P458L	458	Missense	proximal	1	no	13.867	5.057	EPSD	COSMIC	8.102	Loss
CMGC_MAPK_ERK1_MAPK1_ST	P41182	BCL6	P28482	MAPK1	S466	P472L	472	Missense	distal	6	no	11.972	11.566	EPSD	COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q13164	MAPK7	P28482	MAPK1	S210	R205P	205	Missense	distal	-5	no	10.837	10.789	EPSD	COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q13164	MAPK7	P28482	MAPK1	S210	R205C	205	Missense	distal	-5	no	10.837	11.067	EPSD	COSMIC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q13164	MAPK7	P28482	MAPK1	T280	P281S	281	Missense	proximal	1	no	14.924	5.529	EPSD	COSMIC	8.102	Loss
CMGC_MAPK_ERK1_MAPK1_ST	Q13164	MAPK7	P28482	MAPK1	S282	V289L	289	Missense	distal	7	no	14.633	14.639	EPSD	COSMIC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q13164	MAPK7	P28482	MAPK1	S282	A288V	288	Missense	distal	6	no	14.633	14.715	EPSD	COSMIC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q13164	MAPK7	P28482	MAPK1	S282	P281S	281	Missense	proximal	-1	no	14.633	14.590	EPSD	COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q13164	MAPK7	P28482	MAPK1	S421	C414Y	414	Missense	distal	-7	no	13.740	13.742	EPSD	COSMIC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q13164	MAPK7	P28482	MAPK1	S433	M431I	431	Missense	proximal	-2	no	11.860	13.980	EPSD	COSMIC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q13164	MAPK7	P28482	MAPK1	S433	P438L	438	Missense	distal	5	no	11.860	11.647	EPSD	COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q13164	MAPK7	P28482	MAPK1	T553	G550D	550	Missense	distal	-3	no	10.272	10.332	EPSD	COSMIC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q13164	MAPK7	P28482	MAPK1	T553	G558R	558	Missense	distal	5	no	10.272	10.322	EPSD	COSMIC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q13164	MAPK7	P28482	MAPK1	T553	A557V	557	Missense	distal	4	no	10.272	10.266	EPSD	COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q13164	MAPK7	P28482	MAPK1	T553	G558V	558	Missense	distal	5	no	10.272	10.148	EPSD	COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q13164	MAPK7	P28482	MAPK1	T594	A592V	592	Missense	proximal	-2	no	14.134	15.408	EPSD	COSMIC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q13164	MAPK7	P28482	MAPK1	T594	V600L	600	Missense	distal	6	no	14.134	13.942	EPSD	COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q13164	MAPK7	P28482	MAPK1	T594	P591L	591	Missense	distal	-3	no	14.134	13.750	EPSD	COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q13164	MAPK7	P28482	MAPK1	T594	T594M	594	Missense	central	0	yes	14.134	0.000	EPSD	COSMIC	8.102	Loss
CMGC_MAPK_ERK1_MAPK1_ST	Q13164	MAPK7	P28482	MAPK1	T594	T594I	594	Missense	central	0	yes	14.134	0.000	EPSD	COSMIC	8.102	Loss
CMGC_MAPK_ERK1_MAPK1_ST	Q13164	MAPK7	P28482	MAPK1	T594	P589H	589	Missense	distal	-5	no	14.134	14.259	EPSD	COSMIC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q13164	MAPK7	P28482	MAPK1	T733	P728H	728	Missense	distal	-5	no	12.957	13.081	PhosphoSitePlus	COSMIC;GDSC;CCLE	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q13164	MAPK7	P28482	MAPK1	T733	T733I	733	Missense	central	0	yes	12.957	0.000	PhosphoSitePlus	COSMIC	8.102	Loss
CMGC_MAPK_ERK1_MAPK1_ST	Q13164	MAPK7	P28482	MAPK1	S803	L806R	806	Missense	distal	3	no	16.120	16.076	EPSD	COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q13164	MAPK7	P28482	MAPK1	S803	S803F	803	Missense	central	0	yes	16.120	0.000	EPSD	COSMIC	8.102	Loss
CMGC_MAPK_ERK1_MAPK1_ST	Q13164	MAPK7	P28482	MAPK1	S803	M805V	805	Missense	proximal	2	no	16.120	16.257	EPSD	COSMIC;GDSC;CCLE	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q13164	MAPK7	P28482	MAPK1	S803	P804S	804	Missense	proximal	1	no	16.120	6.725	EPSD	COSMIC	8.102	Loss
CMGC_MAPK_ERK1_MAPK1_ST	Q13164	MAPK7	P28482	MAPK1	S803	D809N	809	Missense	distal	6	no	16.120	16.069	EPSD	COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q01844	EWSR1	P28482	MAPK1	T79	T81S	81	Missense	proximal	2	no	12.809	12.832	PhosphoSitePlus	COSMIC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q01844	EWSR1	P28482	MAPK1	T79	T75A	75	Missense	distal	-4	no	12.809	12.829	PhosphoSitePlus	COSMIC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q01844	EWSR1	P28482	MAPK1	T79	P83H	83	Missense	distal	4	no	12.809	12.634	PhosphoSitePlus	COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q01844	EWSR1	P28482	MAPK1	T79	T78I	78	Missense	proximal	-1	no	12.809	12.785	PhosphoSitePlus	COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q01844	EWSR1	P28482	MAPK1	T422	P421S	421	Missense	proximal	-1	no	11.697	11.654	EPSD	COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q9H9Z2	LIN28A	P28482	MAPK1	T189	E193K	193	Missense	distal	4	no	12.220	12.235	EPSD	COSMIC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q9H9Z2	LIN28A	P28482	MAPK1	S200	P205Q	205	Missense	distal	5	no	16.120	15.999	PhosphoSitePlus	COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q9H9Z2	LIN28A	P28482	MAPK1	S200	P201S	201	Missense	proximal	1	no	16.120	6.725	PhosphoSitePlus	COSMIC	8.102	Loss
CMGC_MAPK_ERK1_MAPK1_ST	Q9H9Z2	LIN28A	P28482	MAPK1	S200	P205L	205	Missense	distal	5	no	16.120	15.907	PhosphoSitePlus	COSMIC;GDSC;CCLE	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q9H9Z2	LIN28A	P28482	MAPK1	S200	L204F	204	Missense	distal	4	no	16.120	16.052	PhosphoSitePlus	COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q9H9Z2	LIN28A	P28482	MAPK1	S200	E193K	193	Missense	distal	-7	no	16.120	16.113	PhosphoSitePlus	COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q9H9Z2	LIN28A	P28482	MAPK1	S200	E206K	206	Missense	distal	6	no	16.120	16.143	PhosphoSitePlus	COSMIC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q12772	SREBF2	P28482	MAPK1	S101	S101F	101	Missense	central	0	yes	13.077	0.000	EPSD	COSMIC	8.102	Loss
CMGC_MAPK_ERK1_MAPK1_ST	Q12772	SREBF2	P28482	MAPK1	S101	S99F	99	Missense	proximal	-2	no	13.077	13.270	EPSD	COSMIC;GDSC;CCLE	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q12772	SREBF2	P28482	MAPK1	S106	S101F	101	Missense	distal	-5	no	13.276	13.364	EPSD	COSMIC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q12772	SREBF2	P28482	MAPK1	S106	S99F	99	Missense	distal	-7	no	13.276	13.255	EPSD	COSMIC;GDSC;CCLE	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q12772	SREBF2	P28482	MAPK1	S117	P118S	118	Missense	proximal	1	no	14.074	4.679	EPSD	COSMIC	8.102	Loss
CMGC_MAPK_ERK1_MAPK1_ST	Q12772	SREBF2	P28482	MAPK1	T124	P118S	118	Missense	distal	-6	no	15.491	15.465	EPSD	COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q12772	SREBF2	P28482	MAPK1	T153	P160Q	160	Missense	distal	7	no	10.587	10.716	EPSD	COSMIC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q12772	SREBF2	P28482	MAPK1	T153	V150A	150	Missense	distal	-3	no	10.587	10.527	EPSD	COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q12772	SREBF2	P28482	MAPK1	T153	P160L	160	Missense	distal	7	no	10.587	10.886	EPSD	COSMIC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q12772	SREBF2	P28482	MAPK1	T334	G329W	329	Missense	distal	-5	no	8.067	8.323	EPSD	COSMIC	8.102	Gain
CMGC_MAPK_ERK1_MAPK1_ST	Q12772	SREBF2	P28482	MAPK1	S455	L457F	457	Missense	proximal	2	no	18.586	18.574	PhosphoSitePlus;EPSD	COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q12772	SREBF2	P28482	MAPK1	S455	K462N	462	Missense	distal	7	no	18.586	18.620	PhosphoSitePlus;EPSD	COSMIC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q12772	SREBF2	P28482	MAPK1	S455	K462E	462	Missense	distal	7	no	18.586	18.578	PhosphoSitePlus;EPSD	COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q12772	SREBF2	P28482	MAPK1	S455	A461T	461	Missense	distal	6	no	18.586	18.672	PhosphoSitePlus;EPSD	COSMIC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q12772	SREBF2	P28482	MAPK1	S469	S469F	469	Missense	central	0	yes	17.557	0.000	EPSD	COSMIC	8.102	Loss
CMGC_MAPK_ERK1_MAPK1_ST	Q12772	SREBF2	P28482	MAPK1	S469	S469A	469	Missense	central	0	yes	17.557	0.000	EPSD	COSMIC	8.102	Loss
CMGC_MAPK_ERK1_MAPK1_ST	Q12772	SREBF2	P28482	MAPK1	S469	S469C	469	Missense	central	0	yes	17.557	0.000	EPSD	COSMIC	8.102	Loss
CMGC_MAPK_ERK1_MAPK1_ST	Q12772	SREBF2	P28482	MAPK1	S469	K462E	462	Missense	distal	-7	no	17.557	17.564	EPSD	COSMIC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q12772	SREBF2	P28482	MAPK1	S469	P470S	470	Missense	proximal	1	no	17.557	8.162	EPSD	COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q12772	SREBF2	P28482	MAPK1	S859	S866F	866	Missense	distal	7	no	8.112	8.460	EPSD	COSMIC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q12772	SREBF2	P28482	MAPK1	S914	E910K	910	Missense	distal	-4	no	11.735	11.753	EPSD	COSMIC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q12772	SREBF2	P28482	MAPK1	S1094	S1094F	1094	Missense	central	0	yes	8.783	0.000	EPSD	COSMIC	8.102	Loss
CMGC_MAPK_ERK1_MAPK1_ST	Q12772	SREBF2	P28482	MAPK1	S1094	S1098F	1098	Missense	distal	4	no	8.783	8.605	EPSD	COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q12772	SREBF2	P28482	MAPK1	S1098	S1094F	1094	Missense	distal	-4	no	13.683	13.422	EPSD	COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q12772	SREBF2	P28482	MAPK1	S1098	S1098F	1098	Missense	central	0	yes	13.683	0.000	EPSD	COSMIC	8.102	Loss
CMGC_MAPK_ERK1_MAPK1_ST	Q12772	SREBF2	P28482	MAPK1	S1121	C1122S	1122	Missense	proximal	1	no	4.527	8.581	EPSD	COSMIC	8.102	Gain
CMGC_MAPK_ERK1_MAPK1_ST	P06401	PGR	P28482	MAPK1	S20	P21S	21	Missense	proximal	1	no	16.972	7.577	EPSD	COSMIC	8.102	Loss
CMGC_MAPK_ERK1_MAPK1_ST	P06401	PGR	P28482	MAPK1	S20	V23I	23	Missense	distal	3	no	16.972	17.042	EPSD	COSMIC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P06401	PGR	P28482	MAPK1	S20	A15V	15	Missense	distal	-5	no	16.972	16.943	EPSD	COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P06401	PGR	P28482	MAPK1	S20	G24V	24	Missense	distal	4	no	16.972	16.922	EPSD	COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P06401	PGR	P28482	MAPK1	S20	P26Q	26	Missense	distal	6	no	16.972	16.684	EPSD	COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P06401	PGR	P28482	MAPK1	S25	P31T	31	Missense	distal	6	no	17.333	17.123	EPSD	COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P06401	PGR	P28482	MAPK1	S25	E22K	22	Missense	distal	-3	no	17.333	17.255	EPSD	COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P06401	PGR	P28482	MAPK1	S25	P21S	21	Missense	distal	-4	no	17.333	17.249	EPSD	COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P06401	PGR	P28482	MAPK1	S25	V23I	23	Missense	proximal	-2	no	17.333	17.312	EPSD	COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P06401	PGR	P28482	MAPK1	S25	G24V	24	Missense	proximal	-1	no	17.333	17.362	EPSD	COSMIC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P06401	PGR	P28482	MAPK1	S25	P26Q	26	Missense	proximal	1	no	17.333	8.840	EPSD	COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P06401	PGR	P28482	MAPK1	S102	G97E	97	Missense	distal	-5	no	14.000	13.958	EPSD	COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P06401	PGR	P28482	MAPK1	S102	P103L	103	Missense	proximal	1	no	14.000	5.191	EPSD	COSMIC	8.102	Loss
CMGC_MAPK_ERK1_MAPK1_ST	P06401	PGR	P28482	MAPK1	S102	S99N	99	Missense	distal	-3	no	14.000	14.016	EPSD	COSMIC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P06401	PGR	P28482	MAPK1	S102	P103H	103	Missense	proximal	1	no	14.000	6.177	EPSD	COSMIC	8.102	Loss
CMGC_MAPK_ERK1_MAPK1_ST	P06401	PGR	P28482	MAPK1	S130	P131S	131	Missense	proximal	1	no	13.049	3.654	EPSD	COSMIC	8.102	Loss
CMGC_MAPK_ERK1_MAPK1_ST	P06401	PGR	P28482	MAPK1	S130	T137I	137	Missense	distal	7	no	13.049	13.445	EPSD	COSMIC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P06401	PGR	P28482	MAPK1	S139	F143L	143	Missense	distal	4	no	8.048	8.116	EPSD	COSMIC;GDSC;CCLE	8.102	Gain
CMGC_MAPK_ERK1_MAPK1_ST	P06401	PGR	P28482	MAPK1	S139	T137I	137	Missense	proximal	-2	no	8.048	8.853	EPSD	COSMIC	8.102	Gain
CMGC_MAPK_ERK1_MAPK1_ST	P06401	PGR	P28482	MAPK1	S162	S168F	168	Missense	distal	6	no	18.703	18.262	EPSD	COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P06401	PGR	P28482	MAPK1	S162	R167W	167	Missense	distal	5	no	18.703	18.174	EPSD	COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P06401	PGR	P28482	MAPK1	S162	M165I	165	Missense	distal	3	no	18.703	18.746	EPSD	COSMIC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P06401	PGR	P28482	MAPK1	S190	R187W	187	Missense	distal	-3	no	13.636	12.938	EPSD	COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P06401	PGR	P28482	MAPK1	S190	R187L	187	Missense	distal	-3	no	13.636	13.272	EPSD	COSMIC;CCLE	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P06401	PGR	P28482	MAPK1	S213	A208D	208	Missense	distal	-5	no	15.143	15.088	EPSD	COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P06401	PGR	P28482	MAPK1	S213	V219F	219	Missense	distal	6	no	15.143	14.917	EPSD	COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P06401	PGR	P28482	MAPK1	S294	V300M	300	Missense	distal	6	no	14.860	14.641	PhosphoSitePlus	COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P06401	PGR	P28482	MAPK1	S294	A287V	287	Missense	distal	-7	no	14.860	14.843	PhosphoSitePlus	COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P06401	PGR	P28482	MAPK1	S294	A290E	290	Missense	distal	-4	no	14.860	15.124	PhosphoSitePlus	COSMIC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P06401	PGR	P28482	MAPK1	S294	P291S	291	Missense	distal	-3	no	14.860	14.683	PhosphoSitePlus	COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P06401	PGR	P28482	MAPK1	S344	C347G	347	Missense	distal	3	no	9.114	9.025	EPSD	COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P06401	PGR	P28482	MAPK1	S344	S349L	349	Missense	distal	5	no	9.114	8.883	EPSD	COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P06401	PGR	P28482	MAPK1	S345	C347G	347	Missense	proximal	2	no	15.210	15.488	EPSD	COSMIC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P06401	PGR	P28482	MAPK1	S345	S344T	344	Missense	proximal	-1	no	15.210	15.212	EPSD	COSMIC;GDSC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P06401	PGR	P28482	MAPK1	S345	S349L	349	Missense	distal	4	no	15.210	15.101	EPSD	COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P06401	PGR	P28482	MAPK1	S345	P352L	352	Missense	distal	7	no	15.210	15.510	EPSD	COSMIC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P06401	PGR	P28482	MAPK1	T351	C347G	347	Missense	distal	-4	no	13.423	13.800	EPSD	COSMIC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P06401	PGR	P28482	MAPK1	T351	S344T	344	Missense	distal	-7	no	13.423	13.410	EPSD	COSMIC;GDSC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P06401	PGR	P28482	MAPK1	T351	S349L	349	Missense	proximal	-2	no	13.423	14.340	EPSD	COSMIC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P06401	PGR	P28482	MAPK1	T351	V353A	353	Missense	proximal	2	no	13.423	13.347	EPSD	COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P06401	PGR	P28482	MAPK1	T351	D357N	357	Missense	distal	6	no	13.423	13.372	EPSD	COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P06401	PGR	P28482	MAPK1	T351	P352L	352	Missense	proximal	1	no	13.423	4.613	EPSD	COSMIC	8.102	Loss
CMGC_MAPK_ERK1_MAPK1_ST	P06401	PGR	P28482	MAPK1	S400	R399C	399	Missense	proximal	-1	no	13.209	13.106	EPSD	COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P06401	PGR	P28482	MAPK1	S400	R399S	399	Missense	proximal	-1	no	13.209	13.185	EPSD	COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P06401	PGR	P28482	MAPK1	S400	R402C	402	Missense	proximal	2	no	13.209	12.836	EPSD	COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P06401	PGR	P28482	MAPK1	S400	P401L	401	Missense	proximal	1	no	13.209	4.399	EPSD	COSMIC	8.102	Loss
CMGC_MAPK_ERK1_MAPK1_ST	P06401	PGR	P28482	MAPK1	S400	R402H	402	Missense	proximal	2	no	13.209	12.966	EPSD	COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P06401	PGR	P28482	MAPK1	S549	L542V	542	Missense	distal	-7	no	10.684	10.677	EPSD	COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P06401	PGR	P28482	MAPK1	S549	L545M	545	Missense	distal	-4	no	10.684	10.522	EPSD	COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P06401	PGR	P28482	MAPK1	S549	P547L	547	Missense	proximal	-2	no	10.684	8.766	EPSD	COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P06401	PGR	P28482	MAPK1	S554	P547L	547	Missense	distal	-7	no	12.386	12.373	EPSD	COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P06401	PGR	P28482	MAPK1	S676	I681M	681	Missense	distal	5	no	14.149	14.262	EPSD	COSMIC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P06401	PGR	P28482	MAPK1	S676	I681L	681	Missense	distal	5	no	14.149	14.235	EPSD	COSMIC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P46695	IER3	P28482	MAPK1	T18	T12S	12	Missense	distal	-6	no	15.252	15.276	PhosphoSitePlus	COSMIC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P46695	IER3	P28482	MAPK1	T18	A16D	16	Missense	proximal	-2	no	15.252	15.097	PhosphoSitePlus	COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P46695	IER3	P28482	MAPK1	T123	A127P	127	Missense	distal	4	no	14.252	14.356	EPSD	COSMIC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P46695	IER3	P28482	MAPK1	T123	T123N	123	Missense	central	0	yes	14.252	0.000	EPSD	COSMIC	8.102	Loss
CMGC_MAPK_ERK1_MAPK1_ST	P46695	IER3	P28482	MAPK1	T123	P124L	124	Missense	proximal	1	no	14.252	5.442	EPSD	COSMIC	8.102	Loss
CMGC_MAPK_ERK1_MAPK1_ST	P46695	IER3	P28482	MAPK1	S126	A127P	127	Missense	proximal	1	no	10.888	18.518	EPSD	COSMIC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P46695	IER3	P28482	MAPK1	S126	T123N	123	Missense	distal	-3	no	10.888	10.936	EPSD	COSMIC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P46695	IER3	P28482	MAPK1	S126	P124L	124	Missense	proximal	-2	no	10.888	8.970	EPSD	COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q15596	NCOA2	P28482	MAPK1	S402	S399G	399	Missense	distal	-3	no	13.635	13.623	EPSD	COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q15596	NCOA2	P28482	MAPK1	S402	L395P	395	Missense	distal	-7	no	13.635	13.647	EPSD	COSMIC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q15596	NCOA2	P28482	MAPK1	T457	P458T	458	Missense	proximal	1	no	12.271	3.772	EPSD	COSMIC;GDSC;CCLE	8.102	Loss
CMGC_MAPK_ERK1_MAPK1_ST	Q15596	NCOA2	P28482	MAPK1	S469	S473T	473	Missense	distal	4	no	12.831	12.718	EPSD	COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q15596	NCOA2	P28482	MAPK1	S469	M467I	467	Missense	proximal	-2	no	12.831	14.950	EPSD	COSMIC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q15596	NCOA2	P28482	MAPK1	S469	P470S	470	Missense	proximal	1	no	12.831	3.436	EPSD	COSMIC;GDSC;CCLE	8.102	Loss
CMGC_MAPK_ERK1_MAPK1_ST	Q15596	NCOA2	P28482	MAPK1	S474	S473T	473	Missense	proximal	-1	no	13.633	13.635	EPSD	COSMIC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q15596	NCOA2	P28482	MAPK1	S474	M467I	467	Missense	distal	-7	no	13.633	13.623	EPSD	COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q15596	NCOA2	P28482	MAPK1	S474	P470S	470	Missense	distal	-4	no	13.633	13.550	EPSD	COSMIC;GDSC;CCLE	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q15596	NCOA2	P28482	MAPK1	S474	G480R	480	Missense	distal	6	no	13.633	13.604	EPSD	COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q15596	NCOA2	P28482	MAPK1	S487	G480R	480	Missense	distal	-7	no	11.426	11.439	EPSD	COSMIC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q15596	NCOA2	P28482	MAPK1	S565	V567F	567	Missense	proximal	2	no	14.944	14.838	EPSD	COSMIC;GDSC;CCLE	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q15596	NCOA2	P28482	MAPK1	S655	S662L	662	Missense	distal	7	no	12.120	12.409	EPSD	COSMIC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q15596	NCOA2	P28482	MAPK1	S655	P656S	656	Missense	proximal	1	no	12.120	2.725	EPSD	COSMIC	8.102	Loss
CMGC_MAPK_ERK1_MAPK1_ST	Q15596	NCOA2	P28482	MAPK1	S736	P737S	737	Missense	proximal	1	no	16.880	7.485	PhosphoSitePlus	COSMIC	8.102	Loss
CMGC_MAPK_ERK1_MAPK1_ST	Q15596	NCOA2	P28482	MAPK1	T763	D756V	756	Missense	distal	-7	no	14.681	14.665	EPSD	COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q15596	NCOA2	P28482	MAPK1	S851	A848V	848	Missense	distal	-3	no	14.974	15.033	EPSD	COSMIC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q15596	NCOA2	P28482	MAPK1	S851	E849K	849	Missense	proximal	-2	no	14.974	14.934	EPSD	COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q15596	NCOA2	P28482	MAPK1	S851	G857A	857	Missense	distal	6	no	14.974	14.754	EPSD	COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q15596	NCOA2	P28482	MAPK1	T854	A848V	848	Missense	distal	-6	no	17.168	17.121	EPSD	COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q15596	NCOA2	P28482	MAPK1	T854	E849K	849	Missense	distal	-5	no	17.168	17.145	EPSD	COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q15596	NCOA2	P28482	MAPK1	T854	G857A	857	Missense	distal	3	no	17.168	17.162	EPSD	COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q15596	NCOA2	P28482	MAPK1	S895	T897A	897	Missense	proximal	2	no	17.270	17.191	EPSD	COSMIC;CCLE	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q15596	NCOA2	P28482	MAPK1	S1059	L1064P	1064	Missense	distal	5	no	11.342	11.555	EPSD	COSMIC;CCLE	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q15596	NCOA2	P28482	MAPK1	S1059	P1055L	1055	Missense	distal	-4	no	11.342	11.038	EPSD	COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q15596	NCOA2	P28482	MAPK1	S1072	H1067R	1067	Missense	distal	-5	no	14.422	14.345	EPSD	COSMIC;GDSC;CCLE	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q15596	NCOA2	P28482	MAPK1	S1072	P1073Q	1073	Missense	proximal	1	no	14.422	5.929	EPSD	COSMIC	8.102	Loss
CMGC_MAPK_ERK1_MAPK1_ST	Q15596	NCOA2	P28482	MAPK1	T1273	G1269W	1269	Missense	distal	-4	no	12.258	11.576	EPSD	COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P17676	CEBPB	P28482	MAPK1	S76	H69Q	69	Missense	distal	-7	no	11.892	11.911	EPSD	COSMIC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P05198	EIF2S1	P28482	MAPK1	S26	M30I	30	Missense	distal	4	no	9.629	9.651	EPSD	COSMIC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P05198	EIF2S1	P28482	MAPK1	S35	M30I	30	Missense	distal	-5	no	8.704	8.761	EPSD	COSMIC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P05198	EIF2S1	P28482	MAPK1	S52	L48V	48	Missense	distal	-4	no	8.103	8.053	PhosphoSitePlus	COSMIC	8.102	Loss
CMGC_MAPK_ERK1_MAPK1_ST	P05198	EIF2S1	P28482	MAPK1	S52	R55H	55	Missense	distal	3	no	8.103	8.146	PhosphoSitePlus	COSMIC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P05198	EIF2S1	P28482	MAPK1	S52	R55C	55	Missense	distal	3	no	8.103	8.230	PhosphoSitePlus	COSMIC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	O60504	SORBS3	P28482	MAPK1	T64	Y63H	63	Missense	proximal	-1	no	11.635	11.668	EPSD	COSMIC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	O60504	SORBS3	P28482	MAPK1	T191	T191K	191	Missense	central	0	yes	8.558	0.000	EPSD	COSMIC	8.102	Loss
CMGC_MAPK_ERK1_MAPK1_ST	O60504	SORBS3	P28482	MAPK1	T191	G195E	195	Missense	distal	4	no	8.558	8.580	EPSD	COSMIC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	O60504	SORBS3	P28482	MAPK1	S299	R296M	296	Missense	distal	-3	no	14.575	14.157	EPSD	COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	O60504	SORBS3	P28482	MAPK1	S303	R296M	296	Missense	distal	-7	no	15.032	15.015	EPSD	COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	O60504	SORBS3	P28482	MAPK1	S339	A344V	344	Missense	distal	5	no	13.401	13.418	EPSD	COSMIC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	O60504	SORBS3	P28482	MAPK1	S348	A344V	344	Missense	distal	-4	no	12.996	12.935	EPSD	COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	O60504	SORBS3	P28482	MAPK1	S373	E379K	379	Missense	distal	6	no	13.044	13.067	EPSD	COSMIC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	O60504	SORBS3	P28482	MAPK1	S373	E379G	379	Missense	distal	6	no	13.044	12.933	EPSD	COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	O60504	SORBS3	P28482	MAPK1	S395	A393V	393	Missense	proximal	-2	no	13.769	15.043	EPSD	COSMIC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	O60504	SORBS3	P28482	MAPK1	S530	A537T	537	Missense	distal	7	no	16.487	16.458	EPSD	COSMIC;GDSC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	O60504	SORBS3	P28482	MAPK1	S530	D523E	523	Missense	distal	-7	no	16.487	16.495	EPSD	COSMIC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	O60504	SORBS3	P28482	MAPK1	S530	R532C	532	Missense	proximal	2	no	16.487	16.114	EPSD	COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	O60504	SORBS3	P28482	MAPK1	T534	A540S	540	Missense	distal	6	no	8.101	8.397	EPSD	COSMIC	8.102	Gain
CMGC_MAPK_ERK1_MAPK1_ST	O60504	SORBS3	P28482	MAPK1	S545	S551N	551	Missense	distal	6	no	16.974	16.878	EPSD	COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	O60504	SORBS3	P28482	MAPK1	S545	A540S	540	Missense	distal	-5	no	16.974	16.923	EPSD	COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	O60504	SORBS3	P28482	MAPK1	S545	R550H	550	Missense	distal	5	no	16.974	16.797	EPSD	COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	O60504	SORBS3	P28482	MAPK1	S545	A548T	548	Missense	distal	3	no	16.974	16.957	EPSD	COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	O60504	SORBS3	P28482	MAPK1	S551	S551N	551	Missense	central	0	yes	15.122	0.000	EPSD	COSMIC	8.102	Loss
CMGC_MAPK_ERK1_MAPK1_ST	O60504	SORBS3	P28482	MAPK1	S551	R550H	550	Missense	proximal	-1	no	15.122	15.098	EPSD	COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	O60504	SORBS3	P28482	MAPK1	S551	A548T	548	Missense	distal	-3	no	15.122	15.279	EPSD	COSMIC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	O60504	SORBS3	P28482	MAPK1	S563	R565H	565	Missense	proximal	2	no	12.854	12.611	EPSD	COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	O60504	SORBS3	P28482	MAPK1	T585	T580I	580	Missense	distal	-5	no	14.541	14.647	EPSD	COSMIC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	O60504	SORBS3	P28482	MAPK1	T585	G584D	584	Missense	proximal	-1	no	14.541	14.540	EPSD	COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	O60504	SORBS3	P28482	MAPK1	S606	G603W	603	Missense	distal	-3	no	14.445	13.915	EPSD	COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q13480	GAB1	P28482	MAPK1	S244	D243H	243	Missense	proximal	-1	no	13.472	13.484	EPSD	COSMIC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q13480	GAB1	P28482	MAPK1	S244	R248H	248	Missense	distal	4	no	13.472	13.330	EPSD	COSMIC;GDSC;CCLE	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q13480	GAB1	P28482	MAPK1	S264	S264L	264	Missense	central	0	yes	8.666	0.000	EPSD	COSMIC	8.102	Loss
CMGC_MAPK_ERK1_MAPK1_ST	Q13480	GAB1	P28482	MAPK1	S266	S264L	264	Missense	proximal	-2	no	7.881	8.798	EPSD	COSMIC	8.102	Gain
CMGC_MAPK_ERK1_MAPK1_ST	Q13480	GAB1	P28482	MAPK1	T289	S294L	294	Missense	distal	5	no	16.048	15.817	EPSD	COSMIC;CCLE	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q13480	GAB1	P28482	MAPK1	T289	T289I	289	Missense	central	0	yes	16.048	0.000	EPSD	COSMIC	8.102	Loss
CMGC_MAPK_ERK1_MAPK1_ST	Q13480	GAB1	P28482	MAPK1	T312	D308G	308	Missense	distal	-4	no	17.126	16.790	EPSD	COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q13480	GAB1	P28482	MAPK1	T312	P311A	311	Missense	proximal	-1	no	17.126	17.089	EPSD	COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q13480	GAB1	P28482	MAPK1	T312	D308V	308	Missense	distal	-4	no	17.126	16.786	EPSD	COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q13480	GAB1	P28482	MAPK1	T312	T316A	316	Missense	distal	4	no	17.126	17.145	EPSD	COSMIC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q13480	GAB1	P28482	MAPK1	S355	P356L	356	Missense	proximal	1	no	15.003	6.193	EPSD	COSMIC	8.102	Loss
CMGC_MAPK_ERK1_MAPK1_ST	Q13480	GAB1	P28482	MAPK1	T365	A366V	366	Missense	proximal	1	no	9.723	7.813	EPSD	COSMIC	8.102	Loss
CMGC_MAPK_ERK1_MAPK1_ST	Q13480	GAB1	P28482	MAPK1	S367	A366V	366	Missense	proximal	-1	no	8.625	8.636	EPSD	COSMIC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q13480	GAB1	P28482	MAPK1	S381	S381L	381	Missense	central	0	yes	15.553	0.000	EPSD	COSMIC	8.102	Loss
CMGC_MAPK_ERK1_MAPK1_ST	Q13480	GAB1	P28482	MAPK1	S381	A378S	378	Missense	distal	-3	no	15.553	15.743	EPSD	COSMIC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q13480	GAB1	P28482	MAPK1	S381	I388V	388	Missense	distal	7	no	15.553	15.288	EPSD	COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q13480	GAB1	P28482	MAPK1	S381	T387N	387	Missense	distal	6	no	15.553	15.667	EPSD	COSMIC;GDSC;CCLE	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q13480	GAB1	P28482	MAPK1	S454	P456Q	456	Missense	proximal	2	no	16.090	15.912	EPSD	COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q13480	GAB1	P28482	MAPK1	S454	P449H	449	Missense	distal	-5	no	16.090	16.215	EPSD	COSMIC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q13480	GAB1	P28482	MAPK1	S462	P456Q	456	Missense	distal	-6	no	8.166	8.150	EPSD	COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q13480	GAB1	P28482	MAPK1	S462	F463V	463	Missense	proximal	1	no	8.166	5.195	EPSD	COSMIC	8.102	Loss
CMGC_MAPK_ERK1_MAPK1_ST	Q13480	GAB1	P28482	MAPK1	T503	P510S	510	Missense	distal	7	no	16.804	16.815	EPSD	COSMIC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q13480	GAB1	P28482	MAPK1	S551	R555M	555	Missense	distal	4	no	13.128	12.963	EPSD	COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q13480	GAB1	P28482	MAPK1	S551	E544Q	544	Missense	distal	-7	no	13.128	13.126	EPSD	COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q13480	GAB1	P28482	MAPK1	S551	R555G	555	Missense	distal	4	no	13.128	13.102	EPSD	COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q13480	GAB1	P28482	MAPK1	S551	P552H	552	Missense	proximal	1	no	13.128	5.304	EPSD	COSMIC	8.102	Loss
CMGC_MAPK_ERK1_MAPK1_ST	Q13480	GAB1	P28482	MAPK1	S567	P568S	568	Missense	proximal	1	no	17.912	8.517	EPSD	COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q13480	GAB1	P28482	MAPK1	S567	D560N	560	Missense	distal	-7	no	17.912	17.913	EPSD	COSMIC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q13480	GAB1	P28482	MAPK1	S567	S567F	567	Missense	central	0	yes	17.912	0.000	EPSD	COSMIC	8.102	Loss
CMGC_MAPK_ERK1_MAPK1_ST	Q13480	GAB1	P28482	MAPK1	S567	R569L	569	Missense	proximal	2	no	17.912	17.651	EPSD	COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q13480	GAB1	P28482	MAPK1	S567	R563W	563	Missense	distal	-4	no	17.912	16.969	EPSD	COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q13480	GAB1	P28482	MAPK1	S567	S561Y	561	Missense	distal	-6	no	17.912	17.798	EPSD	COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q13480	GAB1	P28482	MAPK1	S567	D571N	571	Missense	distal	4	no	17.912	17.971	EPSD	COSMIC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q13480	GAB1	P28482	MAPK1	S567	P565S	565	Missense	proximal	-2	no	17.912	15.077	EPSD	COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q13480	GAB1	P28482	MAPK1	S567	R569Q	569	Missense	proximal	2	no	17.912	17.620	EPSD	COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q13480	GAB1	P28482	MAPK1	T638	D631F	631	Missense	distal	-7	no	14.698	14.677	EPSD	COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q13480	GAB1	P28482	MAPK1	T638	P639S	639	Missense	proximal	1	no	14.698	5.304	EPSD	COSMIC;CCLE	8.102	Loss
CMGC_MAPK_ERK1_MAPK1_ST	Q13480	GAB1	P28482	MAPK1	T638	D631Y	631	Missense	distal	-7	no	14.698	14.666	EPSD	COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q13480	GAB1	P28482	MAPK1	T638	D631V	631	Missense	distal	-7	no	14.698	14.683	EPSD	COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q13480	GAB1	P28482	MAPK1	T638	R641H	641	Missense	distal	3	no	14.698	14.741	EPSD	COSMIC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q13480	GAB1	P28482	MAPK1	T638	K644T	644	Missense	distal	6	no	14.698	14.431	EPSD	COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q13480	GAB1	P28482	MAPK1	T638	L632I	632	Missense	distal	-6	no	14.698	14.663	EPSD	COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q13480	GAB1	P28482	MAPK1	T638	D631N	631	Missense	distal	-7	no	14.698	14.699	EPSD	COSMIC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q13480	GAB1	P28482	MAPK1	T638	G635E	635	Missense	distal	-3	no	14.698	14.707	EPSD	COSMIC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q13480	GAB1	P28482	MAPK1	T673	R674P	674	Missense	proximal	1	no	4.187	13.842	EPSD	COSMIC	8.102	Gain
CMGC_MAPK_ERK1_MAPK1_ST	P10275	AR	P28482	MAPK1	T18	A22T	22	Missense	distal	4	no	8.910	8.890	EPSD	COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P10275	AR	P28482	MAPK1	T18	F23L	23	Missense	distal	5	no	8.910	8.876	EPSD	COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P10275	AR	P28482	MAPK1	T18	Q24H	24	Missense	distal	6	no	8.910	8.892	EPSD	COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P10275	AR	P28482	MAPK1	T18	R13W	13	Missense	distal	-5	no	8.910	9.186	EPSD	COSMIC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P10275	AR	P28482	MAPK1	T18	G21A	21	Missense	distal	3	no	8.910	8.904	EPSD	COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P10275	AR	P28482	MAPK1	T18	P12A	12	Missense	distal	-6	no	8.910	8.871	EPSD	COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P10275	AR	P28482	MAPK1	S83	Q79E	79	Missense	distal	-4	no	14.796	14.960	EPSD	COSMIC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P10275	AR	P28482	MAPK1	S83	Q86K	86	Missense	distal	3	no	14.796	14.726	EPSD	COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P10275	AR	P28482	MAPK1	S83	E81Q	81	Missense	proximal	-2	no	14.796	14.182	EPSD	COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P10275	AR	P28482	MAPK1	S83	Q90H	90	Missense	distal	7	no	14.796	14.900	EPSD	COSMIC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P10275	AR	P28482	MAPK1	S83	Q79R	79	Missense	distal	-4	no	14.796	14.899	EPSD	COSMIC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P10275	AR	P28482	MAPK1	S83	P84H	84	Missense	proximal	1	no	14.796	6.972	EPSD	COSMIC	8.102	Loss
CMGC_MAPK_ERK1_MAPK1_ST	P10275	AR	P28482	MAPK1	S96	S96Y	96	Missense	central	0	yes	11.382	0.000	EPSD	COSMIC	8.102	Loss
CMGC_MAPK_ERK1_MAPK1_ST	P10275	AR	P28482	MAPK1	S96	Q90H	90	Missense	distal	-6	no	11.382	11.323	EPSD	COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P10275	AR	P28482	MAPK1	S96	S96F	96	Missense	central	0	yes	11.382	0.000	EPSD	COSMIC	8.102	Loss
CMGC_MAPK_ERK1_MAPK1_ST	P10275	AR	P28482	MAPK1	S258	L257P	257	Missense	proximal	-1	no	13.952	14.012	EPSD	COSMIC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P10275	AR	P28482	MAPK1	S258	R264Q	264	Missense	distal	6	no	13.952	13.771	EPSD	COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P10275	AR	P28482	MAPK1	S258	E252G	252	Missense	distal	-6	no	13.952	13.898	EPSD	COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P10275	AR	P28482	MAPK1	S258	E252K	252	Missense	distal	-6	no	13.952	13.926	EPSD	COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P10275	AR	P28482	MAPK1	S258	E255K	255	Missense	distal	-3	no	13.952	13.874	EPSD	COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P10275	AR	P28482	MAPK1	T282	R280H	280	Missense	proximal	-2	no	13.218	12.282	EPSD	COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P10275	AR	P28482	MAPK1	T282	E289G	289	Missense	distal	7	no	13.218	13.346	EPSD	COSMIC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P10275	AR	P28482	MAPK1	T282	P276S	276	Missense	distal	-6	no	13.218	13.192	EPSD	COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P10275	AR	P28482	MAPK1	T282	P283S	283	Missense	proximal	1	no	13.218	3.824	EPSD	COSMIC	8.102	Loss
CMGC_MAPK_ERK1_MAPK1_ST	P10275	AR	P28482	MAPK1	T282	A278T	278	Missense	distal	-4	no	13.218	13.198	EPSD	COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P10275	AR	P28482	MAPK1	T282	A285D	285	Missense	distal	3	no	13.218	13.227	EPSD	COSMIC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P10275	AR	P28482	MAPK1	T282	A278V	278	Missense	distal	-4	no	13.218	13.158	EPSD	COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P10275	AR	P28482	MAPK1	T282	A285V	285	Missense	distal	3	no	13.218	13.198	EPSD	COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P10275	AR	P28482	MAPK1	S310	D305N	305	Missense	distal	-5	no	12.629	12.584	EPSD	COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P10275	AR	P28482	MAPK1	S310	S310F	310	Missense	central	0	yes	12.629	0.000	EPSD	COSMIC	8.102	Loss
CMGC_MAPK_ERK1_MAPK1_ST	P10275	AR	P28482	MAPK1	S310	E304K	304	Missense	distal	-6	no	12.629	12.603	EPSD	COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P10275	AR	P28482	MAPK1	S310	T306I	306	Missense	distal	-4	no	12.629	12.271	EPSD	COSMIC;GDSC;CCLE	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P10275	AR	P28482	MAPK1	S310	F312L	312	Missense	proximal	2	no	12.629	12.641	EPSD	COSMIC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P10275	AR	P28482	MAPK1	S426	A430T	430	Missense	distal	4	no	14.753	14.734	EPSD	COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P10275	AR	P28482	MAPK1	S426	A420E	420	Missense	distal	-6	no	14.753	14.803	EPSD	COSMIC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P10275	AR	P28482	MAPK1	S426	G421V	421	Missense	distal	-5	no	14.753	14.782	EPSD	COSMIC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P10275	AR	P28482	MAPK1	S426	A430S	430	Missense	distal	4	no	14.753	14.846	EPSD	COSMIC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P10275	AR	P28482	MAPK1	S426	G421R	421	Missense	distal	-5	no	14.753	14.733	EPSD	COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P10275	AR	P28482	MAPK1	S426	S433L	433	Missense	distal	7	no	14.753	15.042	EPSD	COSMIC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P10275	AR	P28482	MAPK1	S426	S424C	424	Missense	proximal	-2	no	14.753	13.821	EPSD	COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P10275	AR	P28482	MAPK1	S426	S424F	424	Missense	proximal	-2	no	14.753	14.947	EPSD	COSMIC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P10275	AR	P28482	MAPK1	S516	P515H	515	Missense	proximal	-1	no	13.880	13.837	PhosphoSitePlus	COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P10275	AR	P28482	MAPK1	S516	E523K	523	Missense	distal	7	no	13.880	13.888	PhosphoSitePlus	COSMIC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P10275	AR	P28482	MAPK1	S516	P515S	515	Missense	proximal	-1	no	13.880	13.837	PhosphoSitePlus	COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P10275	AR	P28482	MAPK1	S651	A646D	646	Missense	distal	-5	no	15.833	15.779	EPSD	COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P10275	AR	P28482	MAPK1	S651	S648R	648	Missense	distal	-3	no	15.833	15.990	EPSD	COSMIC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P10275	AR	P28482	MAPK1	S651	S648N	648	Missense	distal	-3	no	15.833	15.849	EPSD	COSMIC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P10275	AR	P28482	MAPK1	S651	E654K	654	Missense	distal	3	no	15.833	15.840	EPSD	COSMIC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P10275	AR	P28482	MAPK1	S651	S647F	647	Missense	distal	-4	no	15.833	15.572	EPSD	COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P10275	AR	P28482	MAPK1	S651	E655D	655	Missense	distal	4	no	15.833	15.764	EPSD	COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q14934	NFATC4	P28482	MAPK1	S73	P75H	75	Missense	proximal	2	no	13.328	13.198	EPSD	COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q14934	NFATC4	P28482	MAPK1	S73	P66H	66	Missense	distal	-7	no	13.328	13.312	EPSD	COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q14934	NFATC4	P28482	MAPK1	S73	P66A	66	Missense	distal	-7	no	13.328	13.326	EPSD	COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q14934	NFATC4	P28482	MAPK1	S73	P69L	69	Missense	distal	-4	no	13.328	13.024	EPSD	COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q14934	NFATC4	P28482	MAPK1	S73	R77Q	77	Missense	distal	4	no	13.328	13.253	EPSD	COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q14934	NFATC4	P28482	MAPK1	S73	P78A	78	Missense	distal	5	no	13.328	13.186	EPSD	COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q14934	NFATC4	P28482	MAPK1	S73	S73L	73	Missense	central	0	yes	13.328	0.000	EPSD	COSMIC	8.102	Loss
CMGC_MAPK_ERK1_MAPK1_ST	Q14934	NFATC4	P28482	MAPK1	T119	S120Y	120	Missense	proximal	1	no	6.369	8.755	EPSD	COSMIC	8.102	Gain
CMGC_MAPK_ERK1_MAPK1_ST	Q14934	NFATC4	P28482	MAPK1	S122	P125H	125	Missense	distal	3	no	12.332	12.421	EPSD	COSMIC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q14934	NFATC4	P28482	MAPK1	S122	S122C	122	Missense	central	0	yes	12.332	0.000	EPSD	COSMIC	8.102	Loss
CMGC_MAPK_ERK1_MAPK1_ST	Q14934	NFATC4	P28482	MAPK1	S122	S120Y	120	Missense	proximal	-2	no	12.332	13.049	EPSD	COSMIC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q14934	NFATC4	P28482	MAPK1	S122	P123S	123	Missense	proximal	1	no	12.332	2.937	EPSD	COSMIC	8.102	Loss
CMGC_MAPK_ERK1_MAPK1_ST	Q14934	NFATC4	P28482	MAPK1	S122	P125Q	125	Missense	distal	3	no	12.332	12.400	EPSD	COSMIC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q14934	NFATC4	P28482	MAPK1	S122	P127L	127	Missense	distal	5	no	12.332	12.119	EPSD	COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q14934	NFATC4	P28482	MAPK1	S122	T124M	124	Missense	proximal	2	no	12.332	12.192	EPSD	COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q14934	NFATC4	P28482	MAPK1	T124	P125H	125	Missense	proximal	1	no	14.843	7.019	EPSD	COSMIC	8.102	Loss
CMGC_MAPK_ERK1_MAPK1_ST	Q14934	NFATC4	P28482	MAPK1	T124	P128S	128	Missense	distal	4	no	14.843	14.832	EPSD	COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q14934	NFATC4	P28482	MAPK1	T124	S122C	122	Missense	proximal	-2	no	14.843	13.910	EPSD	COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q14934	NFATC4	P28482	MAPK1	T124	S120Y	120	Missense	distal	-4	no	14.843	14.254	EPSD	COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q14934	NFATC4	P28482	MAPK1	T124	P123S	123	Missense	proximal	-1	no	14.843	14.799	EPSD	COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q14934	NFATC4	P28482	MAPK1	T124	P125Q	125	Missense	proximal	1	no	14.843	6.349	EPSD	COSMIC	8.102	Loss
CMGC_MAPK_ERK1_MAPK1_ST	Q14934	NFATC4	P28482	MAPK1	T124	P127L	127	Missense	distal	3	no	14.843	14.932	EPSD	COSMIC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q14934	NFATC4	P28482	MAPK1	T124	A130V	130	Missense	distal	6	no	14.843	14.924	EPSD	COSMIC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q14934	NFATC4	P28482	MAPK1	T124	T124M	124	Missense	central	0	yes	14.843	0.000	EPSD	COSMIC	8.102	Loss
CMGC_MAPK_ERK1_MAPK1_ST	Q14934	NFATC4	P28482	MAPK1	S142	G141W	141	Missense	proximal	-1	no	12.378	12.311	EPSD	COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q14934	NFATC4	P28482	MAPK1	S142	R144I	144	Missense	proximal	2	no	12.378	12.093	EPSD	COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q14934	NFATC4	P28482	MAPK1	S142	P149Q	149	Missense	distal	7	no	12.378	12.507	EPSD	COSMIC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q14934	NFATC4	P28482	MAPK1	S142	R144K	144	Missense	proximal	2	no	12.378	12.197	EPSD	COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q14934	NFATC4	P28482	MAPK1	S142	W138L	138	Missense	distal	-4	no	12.378	13.105	EPSD	COSMIC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q14934	NFATC4	P28482	MAPK1	S168	G163W	163	Missense	distal	-5	no	15.631	15.886	EPSD	COSMIC;GDSC;CCLE	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q14934	NFATC4	P28482	MAPK1	S168	S168N	168	Missense	central	0	yes	15.631	0.000	EPSD	COSMIC	8.102	Loss
CMGC_MAPK_ERK1_MAPK1_ST	Q14934	NFATC4	P28482	MAPK1	S168	G163R	163	Missense	distal	-5	no	15.631	15.610	EPSD	COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q14934	NFATC4	P28482	MAPK1	S168	G162V	162	Missense	distal	-6	no	15.631	15.587	EPSD	COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q14934	NFATC4	P28482	MAPK1	S170	G163W	163	Missense	distal	-7	no	14.021	13.983	EPSD	COSMIC;GDSC;CCLE	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q14934	NFATC4	P28482	MAPK1	S170	S168N	168	Missense	proximal	-2	no	14.021	14.035	EPSD	COSMIC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q14934	NFATC4	P28482	MAPK1	S170	G163R	163	Missense	distal	-7	no	14.021	14.034	EPSD	COSMIC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q14934	NFATC4	P28482	MAPK1	S213	R219I	219	Missense	distal	6	no	14.089	13.529	EPSD	COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q14934	NFATC4	P28482	MAPK1	S213	R208C	208	Missense	distal	-5	no	14.089	14.319	EPSD	COSMIC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q14934	NFATC4	P28482	MAPK1	S213	S217L	217	Missense	distal	4	no	14.089	13.979	EPSD	COSMIC;CCLE	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q14934	NFATC4	P28482	MAPK1	S213	R219Q	219	Missense	distal	6	no	14.089	13.908	EPSD	COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q14934	NFATC4	P28482	MAPK1	S213	S207F	207	Missense	distal	-6	no	14.089	14.005	EPSD	COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q14934	NFATC4	P28482	MAPK1	S213	P216L	216	Missense	distal	3	no	14.089	14.178	EPSD	COSMIC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q14934	NFATC4	P28482	MAPK1	S213	P214Q	214	Missense	proximal	1	no	14.089	5.595	EPSD	COSMIC	8.102	Loss
CMGC_MAPK_ERK1_MAPK1_ST	Q14934	NFATC4	P28482	MAPK1	S213	A206T	206	Missense	distal	-7	no	14.089	14.074	EPSD	COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q14934	NFATC4	P28482	MAPK1	S217	R219I	219	Missense	proximal	2	no	18.009	17.724	EPSD	COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q14934	NFATC4	P28482	MAPK1	S217	S217L	217	Missense	central	0	yes	18.009	0.000	EPSD	COSMIC;CCLE	8.102	Loss
CMGC_MAPK_ERK1_MAPK1_ST	Q14934	NFATC4	P28482	MAPK1	S217	R219Q	219	Missense	proximal	2	no	18.009	17.717	EPSD	COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q14934	NFATC4	P28482	MAPK1	S217	P216L	216	Missense	proximal	-1	no	18.009	17.949	EPSD	COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q14934	NFATC4	P28482	MAPK1	S217	P214Q	214	Missense	distal	-3	no	18.009	17.712	EPSD	COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q14934	NFATC4	P28482	MAPK1	S217	P224T	224	Missense	distal	7	no	18.009	18.172	EPSD	COSMIC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q14934	NFATC4	P28482	MAPK1	S217	R223W	223	Missense	distal	6	no	18.009	17.085	EPSD	COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q14934	NFATC4	P28482	MAPK1	S221	R219I	219	Missense	proximal	-2	no	13.632	13.556	EPSD	COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q14934	NFATC4	P28482	MAPK1	S221	P227Q	227	Missense	distal	6	no	13.632	13.344	EPSD	COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q14934	NFATC4	P28482	MAPK1	S221	P227H	227	Missense	distal	6	no	13.632	13.326	EPSD	COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q14934	NFATC4	P28482	MAPK1	S221	E228K	228	Missense	distal	7	no	13.632	13.639	EPSD	COSMIC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q14934	NFATC4	P28482	MAPK1	S221	S217L	217	Missense	distal	-4	no	13.632	13.411	EPSD	COSMIC;CCLE	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q14934	NFATC4	P28482	MAPK1	S221	R219Q	219	Missense	proximal	-2	no	13.632	12.456	EPSD	COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q14934	NFATC4	P28482	MAPK1	S221	P216L	216	Missense	distal	-5	no	13.632	13.780	EPSD	COSMIC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q14934	NFATC4	P28482	MAPK1	S221	P214Q	214	Missense	distal	-7	no	13.632	13.635	EPSD	COSMIC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q14934	NFATC4	P28482	MAPK1	S221	P224T	224	Missense	distal	3	no	13.632	13.693	EPSD	COSMIC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q14934	NFATC4	P28482	MAPK1	S221	R223W	223	Missense	proximal	2	no	13.632	13.263	EPSD	COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q14934	NFATC4	P28482	MAPK1	S221	T226S	226	Missense	distal	5	no	13.632	13.705	EPSD	COSMIC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q14934	NFATC4	P28482	MAPK1	T226	R219I	219	Missense	distal	-7	no	17.136	17.109	EPSD	COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q14934	NFATC4	P28482	MAPK1	T226	P227Q	227	Missense	proximal	1	no	17.136	8.643	EPSD	COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q14934	NFATC4	P28482	MAPK1	T226	P227H	227	Missense	proximal	1	no	17.136	9.312	EPSD	COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q14934	NFATC4	P28482	MAPK1	T226	R219Q	219	Missense	distal	-7	no	17.136	17.144	EPSD	COSMIC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q14934	NFATC4	P28482	MAPK1	T226	P224T	224	Missense	proximal	-2	no	17.136	14.437	EPSD	COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q14934	NFATC4	P28482	MAPK1	T226	R223W	223	Missense	distal	-3	no	17.136	16.438	EPSD	COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q14934	NFATC4	P28482	MAPK1	T226	W231S	231	Missense	distal	5	no	17.136	17.633	EPSD	COSMIC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q14934	NFATC4	P28482	MAPK1	S237	G235S	235	Missense	proximal	-2	no	13.770	14.130	EPSD	COSMIC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q14934	NFATC4	P28482	MAPK1	S237	R241L	241	Missense	distal	4	no	13.770	13.683	EPSD	COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q14934	NFATC4	P28482	MAPK1	S237	R241Q	241	Missense	distal	4	no	13.770	13.696	EPSD	COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q14934	NFATC4	P28482	MAPK1	S237	W231S	231	Missense	distal	-6	no	13.770	13.956	EPSD	COSMIC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q14934	NFATC4	P28482	MAPK1	T256	P257S	257	Missense	proximal	1	no	12.676	3.281	EPSD	COSMIC	8.102	Loss
CMGC_MAPK_ERK1_MAPK1_ST	Q14934	NFATC4	P28482	MAPK1	T256	R261W	261	Missense	distal	5	no	12.676	12.148	EPSD	COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q14934	NFATC4	P28482	MAPK1	T256	P253L	253	Missense	distal	-3	no	12.676	12.293	EPSD	COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q14934	NFATC4	P28482	MAPK1	T256	P260Q	260	Missense	distal	4	no	12.676	12.568	EPSD	COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q14934	NFATC4	P28482	MAPK1	T256	R261Q	261	Missense	distal	5	no	12.676	12.506	EPSD	COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q14934	NFATC4	P28482	MAPK1	T256	S259F	259	Missense	distal	3	no	12.676	12.739	EPSD	COSMIC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q14934	NFATC4	P28482	MAPK1	S259	P257S	257	Missense	proximal	-2	no	17.826	14.991	EPSD	COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q14934	NFATC4	P28482	MAPK1	S259	R261W	261	Missense	proximal	2	no	17.826	17.457	EPSD	COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q14934	NFATC4	P28482	MAPK1	S259	P253L	253	Missense	distal	-6	no	17.826	17.734	EPSD	COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q14934	NFATC4	P28482	MAPK1	S259	P260Q	260	Missense	proximal	1	no	17.826	9.332	EPSD	COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q14934	NFATC4	P28482	MAPK1	S259	R261Q	261	Missense	proximal	2	no	17.826	17.534	EPSD	COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q14934	NFATC4	P28482	MAPK1	S259	P265L	265	Missense	distal	6	no	17.826	17.419	EPSD	COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q14934	NFATC4	P28482	MAPK1	S259	S259F	259	Missense	central	0	yes	17.826	0.000	EPSD	COSMIC	8.102	Loss
CMGC_MAPK_ERK1_MAPK1_ST	Q14934	NFATC4	P28482	MAPK1	S264	P257S	257	Missense	distal	-7	no	18.314	18.309	EPSD	COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q14934	NFATC4	P28482	MAPK1	S264	R261W	261	Missense	distal	-3	no	18.314	17.616	EPSD	COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q14934	NFATC4	P28482	MAPK1	S264	P260Q	260	Missense	distal	-4	no	18.314	18.121	EPSD	COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q14934	NFATC4	P28482	MAPK1	S264	R261Q	261	Missense	distal	-3	no	18.314	18.037	EPSD	COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q14934	NFATC4	P28482	MAPK1	S264	P265L	265	Missense	proximal	1	no	18.314	9.504	EPSD	COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q14934	NFATC4	P28482	MAPK1	S264	Y271H	271	Missense	distal	7	no	18.314	18.019	EPSD	COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q14934	NFATC4	P28482	MAPK1	S264	R269Q	269	Missense	distal	5	no	18.314	18.144	EPSD	COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q14934	NFATC4	P28482	MAPK1	S264	R269W	269	Missense	distal	5	no	18.314	17.785	EPSD	COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q14934	NFATC4	P28482	MAPK1	S264	R270H	270	Missense	distal	6	no	18.314	18.115	EPSD	COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q14934	NFATC4	P28482	MAPK1	S264	R270C	270	Missense	distal	6	no	18.314	17.554	EPSD	COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q14934	NFATC4	P28482	MAPK1	S264	S259F	259	Missense	distal	-5	no	18.314	18.402	EPSD	COSMIC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q14934	NFATC4	P28482	MAPK1	T276	P277Q	277	Missense	proximal	1	no	13.947	5.454	EPSD	COSMIC	8.102	Loss
CMGC_MAPK_ERK1_MAPK1_ST	Q14934	NFATC4	P28482	MAPK1	T276	S272F	272	Missense	distal	-4	no	13.947	13.686	EPSD	COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q14934	NFATC4	P28482	MAPK1	T276	G275S	275	Missense	proximal	-1	no	13.947	13.958	EPSD	COSMIC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q14934	NFATC4	P28482	MAPK1	T276	S273L	273	Missense	distal	-3	no	13.947	13.740	EPSD	COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q14934	NFATC4	P28482	MAPK1	T276	P282A	282	Missense	distal	6	no	13.947	13.651	EPSD	COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q14934	NFATC4	P28482	MAPK1	T276	Y271H	271	Missense	distal	-5	no	13.947	13.867	EPSD	COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q14934	NFATC4	P28482	MAPK1	T276	R269Q	269	Missense	distal	-7	no	13.947	13.955	EPSD	COSMIC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q14934	NFATC4	P28482	MAPK1	T276	S272P	272	Missense	distal	-4	no	13.947	14.031	EPSD	COSMIC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q14934	NFATC4	P28482	MAPK1	T276	R269W	269	Missense	distal	-7	no	13.947	13.897	EPSD	COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q14934	NFATC4	P28482	MAPK1	T276	S281F	281	Missense	distal	5	no	13.947	13.750	EPSD	COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q14934	NFATC4	P28482	MAPK1	T276	R270H	270	Missense	distal	-6	no	13.947	13.865	EPSD	COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q14934	NFATC4	P28482	MAPK1	T276	R270C	270	Missense	distal	-6	no	13.947	13.773	EPSD	COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q14934	NFATC4	P28482	MAPK1	T276	S274L	274	Missense	proximal	-2	no	13.947	14.864	EPSD	COSMIC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q14934	NFATC4	P28482	MAPK1	S279	R286W	286	Missense	distal	7	no	9.911	10.882	EPSD	COSMIC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q14934	NFATC4	P28482	MAPK1	S279	P277Q	277	Missense	proximal	-2	no	9.911	6.917	EPSD	COSMIC	8.102	Loss
CMGC_MAPK_ERK1_MAPK1_ST	Q14934	NFATC4	P28482	MAPK1	S279	S272F	272	Missense	distal	-7	no	9.911	9.890	EPSD	COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q14934	NFATC4	P28482	MAPK1	S279	G275S	275	Missense	distal	-4	no	9.911	10.177	EPSD	COSMIC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q14934	NFATC4	P28482	MAPK1	S279	S273L	273	Missense	distal	-6	no	9.911	9.845	EPSD	COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q14934	NFATC4	P28482	MAPK1	S279	P282A	282	Missense	distal	3	no	9.911	9.989	EPSD	COSMIC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q14934	NFATC4	P28482	MAPK1	S279	R286H	286	Missense	distal	7	no	9.911	10.130	EPSD	COSMIC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q14934	NFATC4	P28482	MAPK1	S279	S272P	272	Missense	distal	-7	no	9.911	9.915	EPSD	COSMIC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q14934	NFATC4	P28482	MAPK1	S279	S281F	281	Missense	proximal	2	no	9.911	9.779	EPSD	COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q14934	NFATC4	P28482	MAPK1	S279	S274L	274	Missense	distal	-5	no	9.911	9.985	EPSD	COSMIC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q14934	NFATC4	P28482	MAPK1	S281	R286W	286	Missense	distal	5	no	13.613	13.085	EPSD	COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q14934	NFATC4	P28482	MAPK1	S281	P277Q	277	Missense	distal	-4	no	13.613	13.421	EPSD	COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q14934	NFATC4	P28482	MAPK1	S281	S285P	285	Missense	distal	4	no	13.613	13.624	EPSD	COSMIC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q14934	NFATC4	P28482	MAPK1	S281	G275S	275	Missense	distal	-6	no	13.613	13.630	EPSD	COSMIC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q14934	NFATC4	P28482	MAPK1	S281	G288W	288	Missense	distal	7	no	13.613	14.520	EPSD	COSMIC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q14934	NFATC4	P28482	MAPK1	S281	P282A	282	Missense	proximal	1	no	13.613	5.983	EPSD	COSMIC	8.102	Loss
CMGC_MAPK_ERK1_MAPK1_ST	Q14934	NFATC4	P28482	MAPK1	S281	R286H	286	Missense	distal	5	no	13.613	13.437	EPSD	COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q14934	NFATC4	P28482	MAPK1	S281	R287H	287	Missense	distal	6	no	13.613	13.415	EPSD	COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q14934	NFATC4	P28482	MAPK1	S281	R287S	287	Missense	distal	6	no	13.613	13.720	EPSD	COSMIC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q14934	NFATC4	P28482	MAPK1	S281	S281F	281	Missense	central	0	yes	13.613	0.000	EPSD	COSMIC	8.102	Loss
CMGC_MAPK_ERK1_MAPK1_ST	Q14934	NFATC4	P28482	MAPK1	S281	S274L	274	Missense	distal	-7	no	13.613	13.606	EPSD	COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q14934	NFATC4	P28482	MAPK1	S311	P314S	314	Missense	distal	3	no	15.778	15.847	EPSD	COSMIC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q14934	NFATC4	P28482	MAPK1	S311	P312S	312	Missense	proximal	1	no	15.778	6.383	EPSD	COSMIC	8.102	Loss
CMGC_MAPK_ERK1_MAPK1_ST	Q14934	NFATC4	P28482	MAPK1	S311	P304L	304	Missense	distal	-7	no	15.778	15.765	EPSD	COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q14934	NFATC4	P28482	MAPK1	S311	D316Y	316	Missense	distal	5	no	15.778	15.464	EPSD	COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q14934	NFATC4	P28482	MAPK1	S311	F315L	315	Missense	distal	4	no	15.778	15.845	EPSD	COSMIC;CCLE	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q14934	NFATC4	P28482	MAPK1	S334	S335P	335	Missense	proximal	1	no	6.761	16.156	EPSD	COSMIC	8.102	Gain
CMGC_MAPK_ERK1_MAPK1_ST	Q14934	NFATC4	P28482	MAPK1	S382	D376N	376	Missense	distal	-6	no	15.303	15.258	EPSD	COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q14934	NFATC4	P28482	MAPK1	S382	V380A	380	Missense	proximal	-2	no	15.303	14.029	EPSD	COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q14934	NFATC4	P28482	MAPK1	S382	P383T	383	Missense	proximal	1	no	15.303	6.805	EPSD	COSMIC	8.102	Loss
CMGC_MAPK_ERK1_MAPK1_ST	Q14934	NFATC4	P28482	MAPK1	S382	S387F	387	Missense	distal	5	no	15.303	15.106	EPSD	COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q14934	NFATC4	P28482	MAPK1	S382	D376Y	376	Missense	distal	-6	no	15.303	15.140	EPSD	COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q14934	NFATC4	P28482	MAPK1	S395	P396T	396	Missense	proximal	1	no	13.217	4.718	EPSD	COSMIC	8.102	Loss
CMGC_MAPK_ERK1_MAPK1_ST	Q14934	NFATC4	P28482	MAPK1	S395	A402V	402	Missense	distal	7	no	13.217	13.319	EPSD	COSMIC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q14934	NFATC4	P28482	MAPK1	S395	R399K	399	Missense	distal	4	no	13.217	13.227	EPSD	COSMIC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q14934	NFATC4	P28482	MAPK1	S395	G392V	392	Missense	distal	-3	no	13.217	13.098	EPSD	COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q14934	NFATC4	P28482	MAPK1	S395	F398S	398	Missense	distal	3	no	13.217	13.154	EPSD	COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q14934	NFATC4	P28482	MAPK1	S395	I391T	391	Missense	distal	-4	no	13.217	13.574	EPSD	COSMIC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q14934	NFATC4	P28482	MAPK1	S395	S395I	395	Missense	central	0	yes	13.217	0.000	EPSD	COSMIC	8.102	Loss
CMGC_MAPK_ERK1_MAPK1_ST	Q14934	NFATC4	P28482	MAPK1	S592	E589K	589	Missense	distal	-3	no	13.576	13.498	EPSD	COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q14934	NFATC4	P28482	MAPK1	S592	S594L	594	Missense	proximal	2	no	13.576	13.457	EPSD	COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q14934	NFATC4	P28482	MAPK1	S592	P586H	586	Missense	distal	-6	no	13.576	13.502	EPSD	COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q14934	NFATC4	P28482	MAPK1	S592	P593S	593	Missense	proximal	1	no	13.576	4.181	EPSD	COSMIC	8.102	Loss
CMGC_MAPK_ERK1_MAPK1_ST	Q14934	NFATC4	P28482	MAPK1	S592	R599I	599	Missense	distal	7	no	13.576	14.120	EPSD	COSMIC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q14934	NFATC4	P28482	MAPK1	S592	S594R	594	Missense	proximal	2	no	13.576	13.717	EPSD	COSMIC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q14934	NFATC4	P28482	MAPK1	S676	P677A	677	Missense	proximal	1	no	12.895	5.264	PhosphoSitePlus	COSMIC	8.102	Loss
CMGC_MAPK_ERK1_MAPK1_ST	Q14934	NFATC4	P28482	MAPK1	S676	S676N	676	Missense	central	0	yes	12.895	0.000	PhosphoSitePlus	COSMIC	8.102	Loss
CMGC_MAPK_ERK1_MAPK1_ST	Q14934	NFATC4	P28482	MAPK1	S676	G671W	671	Missense	distal	-5	no	12.895	13.150	PhosphoSitePlus	COSMIC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q14934	NFATC4	P28482	MAPK1	S676	R675H	675	Missense	proximal	-1	no	12.895	12.871	PhosphoSitePlus	COSMIC;CCLE	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q14934	NFATC4	P28482	MAPK1	S676	R672W	672	Missense	distal	-4	no	12.895	11.952	PhosphoSitePlus	COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q14934	NFATC4	P28482	MAPK1	S676	S669A	669	Missense	distal	-7	no	12.895	12.896	PhosphoSitePlus	COSMIC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q14934	NFATC4	P28482	MAPK1	S676	G671R	671	Missense	distal	-5	no	12.895	12.874	PhosphoSitePlus	COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q14934	NFATC4	P28482	MAPK1	S676	F683C	683	Missense	distal	7	no	12.895	13.206	PhosphoSitePlus	COSMIC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q14934	NFATC4	P28482	MAPK1	S676	R675C	675	Missense	proximal	-1	no	12.895	12.792	PhosphoSitePlus	COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q14934	NFATC4	P28482	MAPK1	S716	P723L	723	Missense	distal	7	no	13.971	14.270	EPSD	COSMIC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q14934	NFATC4	P28482	MAPK1	S716	P721H	721	Missense	distal	5	no	13.971	13.844	EPSD	COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q14934	NFATC4	P28482	MAPK1	S716	F709C	709	Missense	distal	-7	no	13.971	13.958	EPSD	COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q14934	NFATC4	P28482	MAPK1	S716	R719K	719	Missense	distal	3	no	13.971	13.923	EPSD	COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q14934	NFATC4	P28482	MAPK1	S716	P723S	723	Missense	distal	7	no	13.971	13.982	EPSD	COSMIC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q14934	NFATC4	P28482	MAPK1	S819	G824C	824	Missense	distal	5	no	17.762	17.381	EPSD	COSMIC;CCLE	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q14934	NFATC4	P28482	MAPK1	S819	P817S	817	Missense	proximal	-2	no	17.762	14.928	EPSD	COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q14934	NFATC4	P28482	MAPK1	S819	P820A	820	Missense	proximal	1	no	17.762	10.132	EPSD	COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q14934	NFATC4	P28482	MAPK1	S819	S819F	819	Missense	central	0	yes	17.762	0.000	EPSD	COSMIC	8.102	Loss
CMGC_MAPK_ERK1_MAPK1_ST	Q14934	NFATC4	P28482	MAPK1	S819	A818V	818	Missense	proximal	-1	no	17.762	17.773	EPSD	COSMIC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q14934	NFATC4	P28482	MAPK1	S819	A818S	818	Missense	proximal	-1	no	17.762	17.756	EPSD	COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q14934	NFATC4	P28482	MAPK1	S819	P815H	815	Missense	distal	-4	no	17.762	17.521	EPSD	COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q14934	NFATC4	P28482	MAPK1	S819	P813S	813	Missense	distal	-6	no	17.762	17.736	EPSD	COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q14934	NFATC4	P28482	MAPK1	S819	E823A	823	Missense	distal	4	no	17.762	17.696	EPSD	COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q14934	NFATC4	P28482	MAPK1	S819	R812W	812	Missense	distal	-7	no	17.762	17.711	EPSD	COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q14934	NFATC4	P28482	MAPK1	S819	F826Y	826	Missense	distal	7	no	17.762	17.932	EPSD	COSMIC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q14934	NFATC4	P28482	MAPK1	S819	P815S	815	Missense	distal	-4	no	17.762	17.678	EPSD	COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P02686	MBP	P28482	MAPK1	S16	A12S	12	Missense	distal	-4	no	8.015	8.224	EPSD	COSMIC	8.102	Gain
CMGC_MAPK_ERK1_MAPK1_ST	P02686	MBP	P28482	MAPK1	S141	K138R	138	Missense	distal	-3	no	7.999	8.237	EPSD	COSMIC;GDSC	8.102	Gain
CMGC_MAPK_ERK1_MAPK1_ST	P02686	MBP	P28482	MAPK1	T229	T229M	229	Missense	central	0	yes	15.846	0.000	EPSD	COSMIC	8.102	Loss
CMGC_MAPK_ERK1_MAPK1_ST	P02686	MBP	P28482	MAPK1	T229	R231C	231	Missense	proximal	2	no	15.846	15.473	EPSD	COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P02686	MBP	P28482	MAPK1	T229	S236L	236	Missense	distal	7	no	15.846	16.135	EPSD	COSMIC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P02686	MBP	P28482	MAPK1	T232	T229M	229	Missense	distal	-3	no	16.809	16.581	PhosphoSitePlus	COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P02686	MBP	P28482	MAPK1	T232	G238E	238	Missense	distal	6	no	16.809	16.920	PhosphoSitePlus	COSMIC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P02686	MBP	P28482	MAPK1	T232	P235S	235	Missense	distal	3	no	16.809	16.879	PhosphoSitePlus	COSMIC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P02686	MBP	P28482	MAPK1	T232	R231C	231	Missense	proximal	-1	no	16.809	16.707	PhosphoSitePlus	COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P02686	MBP	P28482	MAPK1	T232	S236L	236	Missense	distal	4	no	16.809	16.700	PhosphoSitePlus	COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P02686	MBP	P28482	MAPK1	S236	R231C	231	Missense	distal	-5	no	7.973	8.203	EPSD	COSMIC	8.102	Gain
CMGC_MAPK_ERK1_MAPK1_ST	P02686	MBP	P28482	MAPK1	S295	R296P	296	Missense	proximal	1	no	7.650	17.305	EPSD	COSMIC	8.102	Gain
CMGC_MAPK_ERK1_MAPK1_ST	P02686	MBP	P28482	MAPK1	S299	S295G	295	Missense	distal	-4	no	15.516	15.250	EPSD	COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P02686	MBP	P28482	MAPK1	S299	R296P	296	Missense	distal	-3	no	15.516	15.536	EPSD	COSMIC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P02686	MBP	P28482	MAPK1	S299	R296C	296	Missense	distal	-3	no	15.516	14.832	EPSD	COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q9UPT5	EXOC7	P28482	MAPK1	S130	P134Q	134	Missense	distal	4	no	14.439	14.330	EPSD	COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q9UPT5	EXOC7	P28482	MAPK1	S250	G246V	246	Missense	distal	-4	no	17.902	17.898	PhosphoSitePlus	COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q9UPT5	EXOC7	P28482	MAPK1	T260	K258N	258	Missense	proximal	-2	no	13.761	13.360	EPSD	COSMIC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q9UPT5	EXOC7	P28482	MAPK1	T260	V266I	266	Missense	distal	6	no	13.761	13.308	EPSD	COSMIC	8.102	Down-regulation
CMGC_GSK_GSK3B_ST	P49841	GSK3B	P49841-2	GSK3B	S9	S9F	9	Missense	central	0	yes	6.632	0.000	EPSD	COSMIC	6.007	Loss
CMGC_GSK_GSK3B_ST	P49841	GSK3B	P49841-2	GSK3B	S9	P16A	16	Missense	distal	7	no	6.632	7.043	EPSD	COSMIC	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	P49841	GSK3B	P49841-2	GSK3B	S9	S2P	2	Missense	distal	-7	no	6.632	6.630	EPSD	COSMIC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	P49841	GSK3B	P49841-2	GSK3B	S25	D31Y	31	Missense	distal	6	no	6.701	6.703	EPSD	COSMIC	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	P49841	GSK3B	P49841-2	GSK3B	S25	S25C	25	Missense	central	0	yes	6.701	0.000	EPSD	COSMIC	6.007	Loss
CMGC_GSK_GSK3B_ST	P49841	GSK3B	P49841-2	GSK3B	S25	A22T	22	Missense	distal	-3	no	6.701	6.706	EPSD	COSMIC	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	P49841	GSK3B	P49841-2	GSK3B	T43	G47C	47	Missense	distal	4	no	7.636	4.746	EPSD	COSMIC	6.007	Loss
CMGC_GSK_GSK3B_ST	P49841	GSK3B	P49841-2	GSK3B	T43	V41G	41	Missense	proximal	-2	no	7.636	7.551	EPSD	COSMIC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	P49841	GSK3B	P49841-2	GSK3B	T43	V37G	37	Missense	distal	-6	no	7.636	7.720	EPSD	COSMIC	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	P49841	GSK3B	P49841-2	GSK3B	S215	Y222C	222	Missense	distal	7	no	7.507	7.457	EPSD	COSMIC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	P49841	GSK3B	P49841-2	GSK3B	S219	Y222C	222	Missense	distal	3	no	6.818	7.025	EPSD	COSMIC	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	P49841	GSK3B	P49841-2	GSK3B	T275	R278M	278	Missense	distal	3	no	7.582	7.762	EPSD	COSMIC	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	P49841	GSK3B	P49841-2	GSK3B	T390	A397V	397	Missense	distal	7	no	5.963	6.041	EPSD	COSMIC;CCLE	6.007	Gain
CMGC_GSK_GSK3A_ST	P10636	MAPT	P49840	GSK3A	S61	E62K	62	Missense	proximal	1	no	71.444	77.365	EPSD	COSMIC	72.838	Gain
CMGC_GSK_GSK3A_ST	P10636	MAPT	P49840	GSK3A	T101	I108V	108	Missense	distal	7	no	73.952	72.950	EPSD	COSMIC	72.838	Down-regulation
CMGC_GSK_GSK3A_ST	P10636	MAPT	P49840	GSK3A	T101	G107R	107	Missense	distal	6	no	73.952	76.311	EPSD	COSMIC	72.838	Up-regulation
CMGC_GSK_GSK3A_ST	P10636	MAPT	P49840	GSK3A	T102	I108V	108	Missense	distal	6	no	76.454	74.537	EPSD	COSMIC	72.838	Down-regulation
CMGC_GSK_GSK3A_ST	P10636	MAPT	P49840	GSK3A	T102	G107R	107	Missense	distal	5	no	76.454	76.900	EPSD	COSMIC	72.838	Up-regulation
CMGC_GSK_GSK3A_ST	P10636	MAPT	P49840	GSK3A	T111	I108V	108	Missense	distal	-3	no	74.941	77.289	EPSD	COSMIC	72.838	Up-regulation
CMGC_GSK_GSK3A_ST	P10636	MAPT	P49840	GSK3A	T111	G107R	107	Missense	distal	-4	no	74.941	76.409	EPSD	COSMIC	72.838	Up-regulation
CMGC_GSK_GSK3A_ST	P10636	MAPT	P49840	GSK3A	S171	P175S	175	Missense	distal	4	no	81.434	87.420	EPSD	COSMIC	72.838	Up-regulation
CMGC_GSK_GSK3A_ST	P10636	MAPT	P49840	GSK3A	S171	A166V	166	Missense	distal	-5	no	81.434	80.248	EPSD	COSMIC;CCLE	72.838	Down-regulation
CMGC_GSK_GSK3A_ST	P10636	MAPT	P49840	GSK3A	S171	E176G	176	Missense	distal	5	no	81.434	81.255	EPSD	COSMIC	72.838	Down-regulation
CMGC_GSK_GSK3A_ST	P10636	MAPT	P49840	GSK3A	S171	D177G	177	Missense	distal	6	no	81.434	80.719	EPSD	COSMIC	72.838	Down-regulation
CMGC_GSK_GSK3A_ST	P10636	MAPT	P49840	GSK3A	S171	E165K	165	Missense	distal	-6	no	81.434	81.640	EPSD	COSMIC	72.838	Up-regulation
CMGC_GSK_GSK3A_ST	P10636	MAPT	P49840	GSK3A	S171	G172V	172	Missense	proximal	1	no	81.434	68.420	EPSD	COSMIC	72.838	Loss
CMGC_GSK_GSK3A_ST	P10636	MAPT	P49840	GSK3A	S227	S227N	227	Missense	central	0	yes	77.653	0.000	EPSD	COSMIC	72.838	Loss
CMGC_GSK_GSK3A_ST	P10636	MAPT	P49840	GSK3A	S227	S227I	227	Missense	central	0	yes	77.653	0.000	EPSD	COSMIC	72.838	Loss
CMGC_GSK_GSK3A_ST	P10636	MAPT	P49840	GSK3A	S227	E226K	226	Missense	proximal	-1	no	77.653	75.648	EPSD	COSMIC	72.838	Down-regulation
CMGC_GSK_GSK3A_ST	P10636	MAPT	P49840	GSK3A	S227	Q230R	230	Missense	distal	3	no	77.653	79.487	EPSD	COSMIC	72.838	Up-regulation
CMGC_GSK_GSK3A_ST	P10636	MAPT	P49840	GSK3A	S227	P233S	233	Missense	distal	6	no	77.653	77.103	EPSD	COSMIC	72.838	Down-regulation
CMGC_GSK_GSK3A_ST	P10636	MAPT	P49840	GSK3A	S227	D225E	225	Missense	proximal	-2	no	77.653	78.055	EPSD	COSMIC	72.838	Up-regulation
CMGC_GSK_GSK3A_ST	P10636	MAPT	P49840	GSK3A	S227	S227G	227	Missense	central	0	yes	77.653	0.000	EPSD	COSMIC	72.838	Loss
CMGC_GSK_GSK3A_ST	P10636	MAPT	P49840	GSK3A	S228	S227N	227	Missense	proximal	-1	no	92.623	92.034	EPSD	COSMIC	72.838	Down-regulation
CMGC_GSK_GSK3A_ST	P10636	MAPT	P49840	GSK3A	S228	S227I	227	Missense	proximal	-1	no	92.623	91.407	EPSD	COSMIC	72.838	Down-regulation
CMGC_GSK_GSK3A_ST	P10636	MAPT	P49840	GSK3A	S228	E226K	226	Missense	proximal	-2	no	92.623	93.984	EPSD	COSMIC	72.838	Up-regulation
CMGC_GSK_GSK3A_ST	P10636	MAPT	P49840	GSK3A	S228	Q230R	230	Missense	proximal	2	no	92.623	93.221	EPSD	COSMIC	72.838	Up-regulation
CMGC_GSK_GSK3A_ST	P10636	MAPT	P49840	GSK3A	S228	P233S	233	Missense	distal	5	no	92.623	87.066	EPSD	COSMIC	72.838	Down-regulation
CMGC_GSK_GSK3A_ST	P10636	MAPT	P49840	GSK3A	S228	D225E	225	Missense	distal	-3	no	92.623	93.905	EPSD	COSMIC	72.838	Up-regulation
CMGC_GSK_GSK3A_ST	P10636	MAPT	P49840	GSK3A	S228	S227G	227	Missense	proximal	-1	no	92.623	92.598	EPSD	COSMIC	72.838	Down-regulation
CMGC_GSK_GSK3A_ST	P10636	MAPT	P49840	GSK3A	S228	S235L	235	Missense	distal	7	no	92.623	92.000	EPSD	COSMIC	72.838	Down-regulation
CMGC_GSK_GSK3A_ST	P10636	MAPT	P49840	GSK3A	S232	S227N	227	Missense	distal	-5	no	85.793	85.151	EPSD	COSMIC	72.838	Down-regulation
CMGC_GSK_GSK3A_ST	P10636	MAPT	P49840	GSK3A	S232	S227I	227	Missense	distal	-5	no	85.793	83.871	EPSD	COSMIC	72.838	Down-regulation
CMGC_GSK_GSK3A_ST	P10636	MAPT	P49840	GSK3A	S232	A237T	237	Missense	distal	5	no	85.793	87.389	EPSD	COSMIC	72.838	Up-regulation
CMGC_GSK_GSK3A_ST	P10636	MAPT	P49840	GSK3A	S232	E226K	226	Missense	distal	-6	no	85.793	85.998	EPSD	COSMIC	72.838	Up-regulation
CMGC_GSK_GSK3A_ST	P10636	MAPT	P49840	GSK3A	S232	Q230R	230	Missense	proximal	-2	no	85.793	86.128	EPSD	COSMIC	72.838	Up-regulation
CMGC_GSK_GSK3A_ST	P10636	MAPT	P49840	GSK3A	S232	S238P	238	Missense	distal	6	no	85.793	86.343	EPSD	COSMIC	72.838	Up-regulation
CMGC_GSK_GSK3A_ST	P10636	MAPT	P49840	GSK3A	S232	P233S	233	Missense	proximal	1	no	85.793	70.101	EPSD	COSMIC	72.838	Loss
CMGC_GSK_GSK3A_ST	P10636	MAPT	P49840	GSK3A	S232	S238F	238	Missense	distal	6	no	85.793	81.235	EPSD	COSMIC	72.838	Down-regulation
CMGC_GSK_GSK3A_ST	P10636	MAPT	P49840	GSK3A	S232	D225E	225	Missense	distal	-7	no	85.793	87.286	EPSD	COSMIC	72.838	Up-regulation
CMGC_GSK_GSK3A_ST	P10636	MAPT	P49840	GSK3A	S232	S227G	227	Missense	distal	-5	no	85.793	85.608	EPSD	COSMIC	72.838	Down-regulation
CMGC_GSK_GSK3A_ST	P10636	MAPT	P49840	GSK3A	S232	S235L	235	Missense	distal	3	no	85.793	83.265	EPSD	COSMIC	72.838	Down-regulation
CMGC_GSK_GSK3A_ST	P10636	MAPT	P49840	GSK3A	S341	A337T	337	Missense	distal	-4	no	79.730	85.486	EPSD	COSMIC	72.838	Up-regulation
CMGC_GSK_GSK3A_ST	P10636	MAPT	P49840	GSK3A	S341	G343R	343	Missense	proximal	2	no	79.730	81.365	EPSD	COSMIC	72.838	Up-regulation
CMGC_GSK_GSK3A_ST	P10636	MAPT	P49840	GSK3A	S341	D345G	345	Missense	distal	4	no	79.730	66.534	EPSD	COSMIC	72.838	Loss
CMGC_GSK_GSK3A_ST	P10636	MAPT	P49840	GSK3A	S341	K347N	347	Missense	distal	6	no	79.730	79.998	EPSD	COSMIC	72.838	Up-regulation
CMGC_GSK_GSK3A_ST	P10636	MAPT	P49840	GSK3A	S355	A361S	361	Missense	distal	6	no	75.547	77.542	EPSD	COSMIC;GDSC;CCLE	72.838	Up-regulation
CMGC_GSK_GSK3A_ST	P10636	MAPT	P49840	GSK3A	S355	P354L	354	Missense	proximal	-1	no	75.547	74.392	EPSD	COSMIC	72.838	Down-regulation
CMGC_GSK_GSK3A_ST	P10636	MAPT	P49840	GSK3A	S382	G385V	385	Missense	distal	3	no	82.900	83.384	EPSD	COSMIC	72.838	Up-regulation
CMGC_GSK_GSK3A_ST	P10636	MAPT	P49840	GSK3A	S382	T386I	386	Missense	distal	4	no	82.900	79.327	EPSD	COSMIC	72.838	Down-regulation
CMGC_GSK_GSK3A_ST	P10636	MAPT	P49840	GSK3A	S382	R377W	377	Missense	distal	-5	no	82.900	83.129	EPSD	COSMIC	72.838	Up-regulation
CMGC_GSK_GSK3A_ST	P10636	MAPT	P49840	GSK3A	S382	D389N	389	Missense	distal	7	no	82.900	83.601	EPSD	COSMIC;GDSC;CCLE	72.838	Up-regulation
CMGC_GSK_GSK3A_ST	P10636	MAPT	P49840	GSK3A	T386	G385V	385	Missense	proximal	-1	no	78.953	79.210	EPSD	COSMIC	72.838	Up-regulation
CMGC_GSK_GSK3A_ST	P10636	MAPT	P49840	GSK3A	T386	T386I	386	Missense	central	0	yes	78.953	0.000	EPSD	COSMIC	72.838	Loss
CMGC_GSK_GSK3A_ST	P10636	MAPT	P49840	GSK3A	T386	D389N	389	Missense	distal	3	no	78.953	79.766	EPSD	COSMIC;GDSC;CCLE	72.838	Up-regulation
CMGC_GSK_GSK3A_ST	P10636	MAPT	P49840	GSK3A	S388	G385V	385	Missense	distal	-3	no	72.779	73.329	EPSD	COSMIC	72.838	Gain
CMGC_GSK_GSK3A_ST	P10636	MAPT	P49840	GSK3A	S396	D389N	389	Missense	distal	-7	no	71.947	73.647	EPSD;PhosphoSitePlus	COSMIC;GDSC;CCLE	72.838	Gain
CMGC_GSK_GSK3A_ST	P10636	MAPT	P49840	GSK3A	S411	L410F	410	Missense	proximal	-1	no	99.189	97.096	EPSD	COSMIC	72.838	Down-regulation
CMGC_GSK_GSK3A_ST	P10636	MAPT	P49840	GSK3A	S411	P412S	412	Missense	proximal	1	no	99.189	83.497	EPSD	COSMIC	72.838	Down-regulation
CMGC_GSK_GSK3A_ST	P10636	MAPT	P49840	GSK3A	T416	L410F	410	Missense	distal	-6	no	86.329	87.779	EPSD	COSMIC	72.838	Up-regulation
CMGC_GSK_GSK3A_ST	P10636	MAPT	P49840	GSK3A	T416	P412S	412	Missense	distal	-4	no	86.329	89.915	EPSD	COSMIC	72.838	Up-regulation
CMGC_GSK_GSK3A_ST	P10636	MAPT	P49840	GSK3A	S437	S443Y	443	Missense	distal	6	no	72.985	73.656	EPSD	COSMIC	72.838	Up-regulation
CMGC_GSK_GSK3A_ST	P10636	MAPT	P49840	GSK3A	S438	S443Y	443	Missense	distal	5	no	99.970	99.174	EPSD	COSMIC	72.838	Down-regulation
CMGC_GSK_GSK3A_ST	P10636	MAPT	P49840	GSK3A	S447	S443Y	443	Missense	distal	-4	no	81.913	81.032	EPSD	COSMIC	72.838	Down-regulation
CMGC_GSK_GSK3A_ST	P10636	MAPT	P49840	GSK3A	S447	S447P	447	Missense	central	0	yes	81.913	0.000	EPSD	COSMIC	72.838	Loss
CMGC_GSK_GSK3A_ST	P10636	MAPT	P49840	GSK3A	S447	R448Q	448	Missense	proximal	1	no	81.913	79.889	EPSD	COSMIC	72.838	Down-regulation
CMGC_GSK_GSK3A_ST	P10636	MAPT	P49840	GSK3A	S451	S447P	447	Missense	distal	-4	no	82.495	78.908	EPSD	COSMIC	72.838	Down-regulation
CMGC_GSK_GSK3A_ST	P10636	MAPT	P49840	GSK3A	S451	R448Q	448	Missense	distal	-3	no	82.495	82.146	EPSD	COSMIC	72.838	Down-regulation
CMGC_GSK_GSK3A_ST	P10636	MAPT	P49840	GSK3A	T466	T466M	466	Missense	central	0	yes	84.654	0.000	EPSD	COSMIC;GDSC;CCLE	72.838	Loss
CMGC_GSK_GSK3A_ST	P10636	MAPT	P49840	GSK3A	T466	K467T	467	Missense	proximal	1	no	84.654	82.607	EPSD	COSMIC	72.838	Down-regulation
CMGC_GSK_GSK3A_ST	P10636	MAPT	P49840	GSK3A	T470	T466M	466	Missense	distal	-4	no	87.288	89.363	EPSD	COSMIC;GDSC;CCLE	72.838	Up-regulation
CMGC_GSK_GSK3A_ST	P10636	MAPT	P49840	GSK3A	T470	K467T	467	Missense	distal	-3	no	87.288	89.093	EPSD	COSMIC	72.838	Up-regulation
CMGC_GSK_GSK3A_ST	P10636	MAPT	P49840	GSK3A	T470	P477L	477	Missense	distal	7	no	87.288	86.325	EPSD	COSMIC	72.838	Down-regulation
CMGC_GSK_GSK3A_ST	P10636	MAPT	P49840	GSK3A	T470	P477S	477	Missense	distal	7	no	87.288	86.947	EPSD	COSMIC	72.838	Down-regulation
CMGC_GSK_GSK3A_ST	P10636	MAPT	P49840	GSK3A	T492	R487K	487	Missense	distal	-5	no	79.582	80.351	EPSD	COSMIC	72.838	Up-regulation
CMGC_GSK_GSK3A_ST	P10636	MAPT	P49840	GSK3A	T492	K491R	491	Missense	proximal	-1	no	79.582	80.241	EPSD	COSMIC	72.838	Up-regulation
CMGC_GSK_GSK3A_ST	P10636	MAPT	P49840	GSK3A	T492	R487G	487	Missense	distal	-5	no	79.582	81.071	EPSD	COSMIC	72.838	Up-regulation
CMGC_GSK_GSK3A_ST	P10636	MAPT	P49840	GSK3A	T492	A495T	495	Missense	distal	3	no	79.582	80.962	EPSD	COSMIC	72.838	Up-regulation
CMGC_GSK_GSK3A_ST	P10636	MAPT	P49840	GSK3A	T492	P493L	493	Missense	proximal	1	no	79.582	65.530	EPSD	COSMIC	72.838	Loss
CMGC_GSK_GSK3A_ST	P10636	MAPT	P49840	GSK3A	T498	K491R	491	Missense	distal	-7	no	93.228	91.657	EPSD	COSMIC	72.838	Down-regulation
CMGC_GSK_GSK3A_ST	P10636	MAPT	P49840	GSK3A	T498	A495T	495	Missense	distal	-3	no	93.228	94.055	EPSD	COSMIC	72.838	Up-regulation
CMGC_GSK_GSK3A_ST	P10636	MAPT	P49840	GSK3A	T498	P493L	493	Missense	distal	-5	no	93.228	91.665	EPSD	COSMIC	72.838	Down-regulation
CMGC_GSK_GSK3A_ST	P10636	MAPT	P49840	GSK3A	S501	P506S	506	Missense	distal	5	no	88.008	82.451	EPSD	COSMIC	72.838	Down-regulation
CMGC_GSK_GSK3A_ST	P10636	MAPT	P49840	GSK3A	S501	A495T	495	Missense	distal	-6	no	88.008	87.426	EPSD	COSMIC	72.838	Down-regulation
CMGC_GSK_GSK3A_ST	P10636	MAPT	P49840	GSK3A	S501	P506L	506	Missense	distal	5	no	88.008	78.834	EPSD	COSMIC	72.838	Down-regulation
CMGC_GSK_GSK3A_ST	P10636	MAPT	P49840	GSK3A	S502	P506S	506	Missense	distal	4	no	75.018	81.004	EPSD	COSMIC	72.838	Up-regulation
CMGC_GSK_GSK3A_ST	P10636	MAPT	P49840	GSK3A	S502	A495T	495	Missense	distal	-7	no	75.018	74.907	EPSD	COSMIC	72.838	Down-regulation
CMGC_GSK_GSK3A_ST	P10636	MAPT	P49840	GSK3A	S502	G509V	509	Missense	distal	7	no	75.018	73.824	EPSD	COSMIC	72.838	Down-regulation
CMGC_GSK_GSK3A_ST	P10636	MAPT	P49840	GSK3A	S502	P506L	506	Missense	distal	4	no	75.018	75.594	EPSD	COSMIC	72.838	Up-regulation
CMGC_GSK_GSK3A_ST	P10636	MAPT	P49840	GSK3A	S508	P506S	506	Missense	proximal	-2	no	80.422	80.270	EPSD	COSMIC	72.838	Down-regulation
CMGC_GSK_GSK3A_ST	P10636	MAPT	P49840	GSK3A	S508	R511C	511	Missense	distal	3	no	80.422	75.822	EPSD	COSMIC;CCLE	72.838	Down-regulation
CMGC_GSK_GSK3A_ST	P10636	MAPT	P49840	GSK3A	S508	G509V	509	Missense	proximal	1	no	80.422	67.408	EPSD	COSMIC	72.838	Loss
CMGC_GSK_GSK3A_ST	P10636	MAPT	P49840	GSK3A	S508	P506L	506	Missense	proximal	-2	no	80.422	79.555	EPSD	COSMIC	72.838	Down-regulation
CMGC_GSK_GSK3A_ST	P10636	MAPT	P49840	GSK3A	S512	P506S	506	Missense	distal	-6	no	92.762	92.708	EPSD	COSMIC	72.838	Down-regulation
CMGC_GSK_GSK3A_ST	P10636	MAPT	P49840	GSK3A	S512	G518V	518	Missense	distal	6	no	92.762	90.102	EPSD	COSMIC	72.838	Down-regulation
CMGC_GSK_GSK3A_ST	P10636	MAPT	P49840	GSK3A	S512	R511C	511	Missense	proximal	-1	no	92.762	92.095	EPSD	COSMIC;CCLE	72.838	Down-regulation
CMGC_GSK_GSK3A_ST	P10636	MAPT	P49840	GSK3A	S512	G509V	509	Missense	distal	-3	no	92.762	93.312	EPSD	COSMIC	72.838	Up-regulation
CMGC_GSK_GSK3A_ST	P10636	MAPT	P49840	GSK3A	S512	P506L	506	Missense	distal	-6	no	92.762	92.888	EPSD	COSMIC	72.838	Up-regulation
CMGC_GSK_GSK3A_ST	P10636	MAPT	P49840	GSK3A	S515	G521V	521	Missense	distal	6	no	88.526	85.866	EPSD	COSMIC	72.838	Down-regulation
CMGC_GSK_GSK3A_ST	P10636	MAPT	P49840	GSK3A	S515	G518V	518	Missense	distal	3	no	88.526	89.010	EPSD	COSMIC	72.838	Up-regulation
CMGC_GSK_GSK3A_ST	P10636	MAPT	P49840	GSK3A	S515	R511C	511	Missense	distal	-4	no	88.526	67.816	EPSD	COSMIC;CCLE	72.838	Loss
CMGC_GSK_GSK3A_ST	P10636	MAPT	P49840	GSK3A	S515	G509V	509	Missense	distal	-6	no	88.526	89.329	EPSD	COSMIC	72.838	Up-regulation
CMGC_GSK_GSK3A_ST	P10636	MAPT	P49840	GSK3A	S516	G521V	521	Missense	distal	5	no	94.559	92.060	EPSD	COSMIC	72.838	Down-regulation
CMGC_GSK_GSK3A_ST	P10636	MAPT	P49840	GSK3A	S516	G518V	518	Missense	proximal	2	no	94.559	94.909	EPSD	COSMIC	72.838	Up-regulation
CMGC_GSK_GSK3A_ST	P10636	MAPT	P49840	GSK3A	S516	R511C	511	Missense	distal	-5	no	94.559	93.875	EPSD	COSMIC;CCLE	72.838	Down-regulation
CMGC_GSK_GSK3A_ST	P10636	MAPT	P49840	GSK3A	S516	G509V	509	Missense	distal	-7	no	94.559	94.449	EPSD	COSMIC	72.838	Down-regulation
CMGC_GSK_GSK3A_ST	P10636	MAPT	P49840	GSK3A	S519	G521V	521	Missense	proximal	2	no	91.776	92.127	EPSD	COSMIC	72.838	Up-regulation
CMGC_GSK_GSK3A_ST	P10636	MAPT	P49840	GSK3A	S519	R526H	526	Missense	distal	7	no	91.776	92.249	EPSD	COSMIC	72.838	Up-regulation
CMGC_GSK_GSK3A_ST	P10636	MAPT	P49840	GSK3A	S519	G518V	518	Missense	proximal	-1	no	91.776	92.033	EPSD	COSMIC	72.838	Up-regulation
CMGC_GSK_GSK3A_ST	P10636	MAPT	P49840	GSK3A	T522	G521V	521	Missense	proximal	-1	no	90.876	91.133	EPSD	COSMIC	72.838	Up-regulation
CMGC_GSK_GSK3A_ST	P10636	MAPT	P49840	GSK3A	T522	R526H	526	Missense	distal	4	no	90.876	72.234	EPSD	COSMIC	72.838	Loss
CMGC_GSK_GSK3A_ST	P10636	MAPT	P49840	GSK3A	T522	G518V	518	Missense	distal	-4	no	90.876	89.936	EPSD	COSMIC	72.838	Down-regulation
CMGC_GSK_GSK3A_ST	P10636	MAPT	P49840	GSK3A	T522	R528S	528	Missense	distal	6	no	90.876	89.470	EPSD	COSMIC	72.838	Down-regulation
CMGC_GSK_GSK3A_ST	P10636	MAPT	P49840	GSK3A	S525	G521V	521	Missense	distal	-4	no	84.428	83.487	EPSD	COSMIC	72.838	Down-regulation
CMGC_GSK_GSK3A_ST	P10636	MAPT	P49840	GSK3A	S525	R526H	526	Missense	proximal	1	no	84.428	66.667	EPSD	COSMIC	72.838	Loss
CMGC_GSK_GSK3A_ST	P10636	MAPT	P49840	GSK3A	S525	G518V	518	Missense	distal	-7	no	84.428	84.318	EPSD	COSMIC	72.838	Down-regulation
CMGC_GSK_GSK3A_ST	P10636	MAPT	P49840	GSK3A	S525	R528S	528	Missense	distal	3	no	84.428	84.142	EPSD	COSMIC	72.838	Down-regulation
CMGC_GSK_GSK3A_ST	P10636	MAPT	P49840	GSK3A	S525	P530S	530	Missense	distal	5	no	84.428	78.871	EPSD	COSMIC	72.838	Down-regulation
CMGC_GSK_GSK3A_ST	P10636	MAPT	P49840	GSK3A	S527	G521V	521	Missense	distal	-6	no	90.290	91.094	EPSD	COSMIC	72.838	Up-regulation
CMGC_GSK_GSK3A_ST	P10636	MAPT	P49840	GSK3A	S527	R526H	526	Missense	proximal	-1	no	90.290	90.739	EPSD	COSMIC	72.838	Up-regulation
CMGC_GSK_GSK3A_ST	P10636	MAPT	P49840	GSK3A	S527	R528S	528	Missense	proximal	1	no	90.290	83.251	EPSD	COSMIC	72.838	Down-regulation
CMGC_GSK_GSK3A_ST	P10636	MAPT	P49840	GSK3A	S527	P530S	530	Missense	distal	3	no	90.290	88.958	EPSD	COSMIC	72.838	Down-regulation
CMGC_GSK_GSK3A_ST	P10636	MAPT	P49840	GSK3A	T529	R526H	526	Missense	distal	-3	no	77.055	77.784	EPSD	COSMIC	72.838	Up-regulation
CMGC_GSK_GSK3A_ST	P10636	MAPT	P49840	GSK3A	T529	R528S	528	Missense	proximal	-1	no	77.055	77.353	EPSD	COSMIC	72.838	Up-regulation
CMGC_GSK_GSK3A_ST	P10636	MAPT	P49840	GSK3A	T529	P530S	530	Missense	proximal	1	no	77.055	61.363	EPSD	COSMIC	72.838	Loss
CMGC_GSK_GSK3A_ST	P10636	MAPT	P49840	GSK3A	T529	P536H	536	Missense	distal	7	no	77.055	76.651	EPSD	COSMIC	72.838	Down-regulation
CMGC_GSK_GSK3A_ST	P10636	MAPT	P49840	GSK3A	T529	P535Q	535	Missense	distal	6	no	77.055	78.965	EPSD	COSMIC	72.838	Up-regulation
CMGC_GSK_GSK3A_ST	P10636	MAPT	P49840	GSK3A	S531	R526H	526	Missense	distal	-5	no	72.926	73.127	EPSD	COSMIC	72.838	Up-regulation
CMGC_GSK_GSK3A_ST	P10636	MAPT	P49840	GSK3A	S531	R528S	528	Missense	distal	-3	no	72.926	73.179	EPSD	COSMIC	72.838	Up-regulation
CMGC_GSK_GSK3A_ST	P10636	MAPT	P49840	GSK3A	S531	P530S	530	Missense	proximal	-1	no	72.926	72.029	EPSD	COSMIC	72.838	Loss
CMGC_GSK_GSK3A_ST	P10636	MAPT	P49840	GSK3A	S531	P536H	536	Missense	distal	5	no	72.926	61.286	EPSD	COSMIC	72.838	Loss
CMGC_GSK_GSK3A_ST	P10636	MAPT	P49840	GSK3A	S531	P535Q	535	Missense	distal	4	no	72.926	64.898	EPSD	COSMIC	72.838	Loss
CMGC_GSK_GSK3A_ST	P10636	MAPT	P49840	GSK3A	T534	R528S	528	Missense	distal	-6	no	83.002	82.614	EPSD	COSMIC	72.838	Down-regulation
CMGC_GSK_GSK3A_ST	P10636	MAPT	P49840	GSK3A	T534	P530S	530	Missense	distal	-4	no	83.002	86.588	EPSD	COSMIC	72.838	Up-regulation
CMGC_GSK_GSK3A_ST	P10636	MAPT	P49840	GSK3A	T534	P536H	536	Missense	proximal	2	no	83.002	81.680	EPSD	COSMIC	72.838	Down-regulation
CMGC_GSK_GSK3A_ST	P10636	MAPT	P49840	GSK3A	T534	P535Q	535	Missense	proximal	1	no	83.002	72.325	EPSD	COSMIC	72.838	Loss
CMGC_GSK_GSK3A_ST	P10636	MAPT	P49840	GSK3A	T534	E539Q	539	Missense	distal	5	no	83.002	78.014	EPSD	COSMIC	72.838	Down-regulation
CMGC_GSK_GSK3A_ST	P10636	MAPT	P49840	GSK3A	T548	P550S	550	Missense	proximal	2	no	106.376	105.687	EPSD	COSMIC	72.838	Down-regulation
CMGC_GSK_GSK3A_ST	P10636	MAPT	P49840	GSK3A	T548	P553R	553	Missense	distal	5	no	106.376	101.231	EPSD	COSMIC	72.838	Down-regulation
CMGC_GSK_GSK3A_ST	P10636	MAPT	P49840	GSK3A	T548	P553L	553	Missense	distal	5	no	106.376	97.202	EPSD	COSMIC	72.838	Down-regulation
CMGC_GSK_GSK3A_ST	P10636	MAPT	P49840	GSK3A	T548	P549L	549	Missense	proximal	1	no	106.376	92.324	EPSD	COSMIC	72.838	Down-regulation
CMGC_GSK_GSK3A_ST	P10636	MAPT	P49840	GSK3A	T548	S555F	555	Missense	distal	7	no	106.376	103.956	EPSD	COSMIC	72.838	Down-regulation
CMGC_GSK_GSK3A_ST	P10636	MAPT	P49840	GSK3A	T548	P553Q	553	Missense	distal	5	no	106.376	95.977	EPSD	COSMIC	72.838	Down-regulation
CMGC_GSK_GSK3A_ST	P10636	MAPT	P49840	GSK3A	S552	P550S	550	Missense	proximal	-2	no	86.324	86.172	EPSD	COSMIC	72.838	Down-regulation
CMGC_GSK_GSK3A_ST	P10636	MAPT	P49840	GSK3A	S552	R559C	559	Missense	distal	7	no	86.324	86.047	EPSD	COSMIC	72.838	Down-regulation
CMGC_GSK_GSK3A_ST	P10636	MAPT	P49840	GSK3A	S552	P553R	553	Missense	proximal	1	no	86.324	77.671	EPSD	COSMIC	72.838	Down-regulation
CMGC_GSK_GSK3A_ST	P10636	MAPT	P49840	GSK3A	S552	P553L	553	Missense	proximal	1	no	86.324	72.272	EPSD	COSMIC	72.838	Loss
CMGC_GSK_GSK3A_ST	P10636	MAPT	P49840	GSK3A	S552	P549L	549	Missense	distal	-3	no	86.324	84.580	EPSD	COSMIC	72.838	Down-regulation
CMGC_GSK_GSK3A_ST	P10636	MAPT	P49840	GSK3A	S552	S555F	555	Missense	distal	3	no	86.324	82.957	EPSD	COSMIC	72.838	Down-regulation
CMGC_GSK_GSK3A_ST	P10636	MAPT	P49840	GSK3A	S552	P553Q	553	Missense	proximal	1	no	86.324	75.647	EPSD	COSMIC	72.838	Down-regulation
CMGC_GSK_GSK3A_ST	P10636	MAPT	P49840	GSK3A	S554	P550S	550	Missense	distal	-4	no	69.532	73.119	EPSD	COSMIC	72.838	Gain
CMGC_GSK_GSK3A_ST	P10636	MAPT	P49840	GSK3A	S555	P550S	550	Missense	distal	-5	no	79.672	79.759	EPSD	COSMIC	72.838	Up-regulation
CMGC_GSK_GSK3A_ST	P10636	MAPT	P49840	GSK3A	S555	R559C	559	Missense	distal	4	no	79.672	15.654	EPSD	COSMIC	72.838	Loss
CMGC_GSK_GSK3A_ST	P10636	MAPT	P49840	GSK3A	S555	P553R	553	Missense	proximal	-2	no	79.672	79.884	EPSD	COSMIC	72.838	Up-regulation
CMGC_GSK_GSK3A_ST	P10636	MAPT	P49840	GSK3A	S555	P553L	553	Missense	proximal	-2	no	79.672	78.805	EPSD	COSMIC	72.838	Down-regulation
CMGC_GSK_GSK3A_ST	P10636	MAPT	P49840	GSK3A	S555	P549L	549	Missense	distal	-6	no	79.672	79.798	EPSD	COSMIC	72.838	Up-regulation
CMGC_GSK_GSK3A_ST	P10636	MAPT	P49840	GSK3A	S555	S555F	555	Missense	central	0	yes	79.672	0.000	EPSD	COSMIC	72.838	Loss
CMGC_GSK_GSK3A_ST	P10636	MAPT	P49840	GSK3A	S555	P553Q	553	Missense	proximal	-2	no	79.672	79.548	EPSD	COSMIC	72.838	Down-regulation
CMGC_GSK_GSK3A_ST	P10636	MAPT	P49840	GSK3A	S558	V565M	565	Missense	distal	7	no	84.189	84.429	EPSD	COSMIC	72.838	Up-regulation
CMGC_GSK_GSK3A_ST	P10636	MAPT	P49840	GSK3A	S558	R559C	559	Missense	proximal	1	no	84.189	65.800	EPSD	COSMIC	72.838	Loss
CMGC_GSK_GSK3A_ST	P10636	MAPT	P49840	GSK3A	S558	P553R	553	Missense	distal	-5	no	84.189	82.602	EPSD	COSMIC	72.838	Down-regulation
CMGC_GSK_GSK3A_ST	P10636	MAPT	P49840	GSK3A	S558	P553L	553	Missense	distal	-5	no	84.189	82.626	EPSD	COSMIC	72.838	Down-regulation
CMGC_GSK_GSK3A_ST	P10636	MAPT	P49840	GSK3A	S558	S555F	555	Missense	distal	-3	no	84.189	82.960	EPSD	COSMIC	72.838	Down-regulation
CMGC_GSK_GSK3A_ST	P10636	MAPT	P49840	GSK3A	S558	P553Q	553	Missense	distal	-5	no	84.189	84.951	EPSD	COSMIC	72.838	Up-regulation
CMGC_GSK_GSK3A_ST	P10636	MAPT	P49840	GSK3A	T562	P566S	566	Missense	distal	4	no	67.947	73.934	EPSD	COSMIC	72.838	Gain
CMGC_GSK_GSK3A_ST	P10636	MAPT	P49840	GSK3A	S575	T580N	580	Missense	distal	5	no	72.897	50.453	EPSD	COSMIC	72.838	Loss
CMGC_GSK_GSK3A_ST	P10636	MAPT	P49840	GSK3A	S575	G578S	578	Missense	distal	3	no	72.897	73.504	EPSD	COSMIC	72.838	Up-regulation
CMGC_GSK_GSK3A_ST	P10636	MAPT	P49840	GSK3A	S575	K571E	571	Missense	distal	-4	no	72.897	74.691	EPSD	COSMIC	72.838	Up-regulation
CMGC_GSK_GSK3A_ST	P10636	MAPT	P49840	GSK3A	S575	P568S	568	Missense	distal	-7	no	72.897	72.742	EPSD	COSMIC	72.838	Loss
CMGC_GSK_GSK3A_ST	P10636	MAPT	P49840	GSK3A	S579	T580N	580	Missense	proximal	1	no	86.905	35.421	EPSD	COSMIC	72.838	Loss
CMGC_GSK_GSK3A_ST	P10636	MAPT	P49840	GSK3A	S579	G578S	578	Missense	proximal	-1	no	86.905	86.929	EPSD	COSMIC	72.838	Up-regulation
CMGC_GSK_GSK3A_ST	P10636	MAPT	P49840	GSK3A	S606	N613D	613	Missense	distal	7	no	73.401	72.699	EPSD	COSMIC	72.838	Loss
CMGC_GSK_GSK3A_ST	P10636	MAPT	P49840	GSK3A	S606	S602G	602	Missense	distal	-4	no	73.401	68.563	EPSD	COSMIC	72.838	Loss
CMGC_GSK_GSK3A_ST	P10636	MAPT	P49840	GSK3A	S606	C608W	608	Missense	proximal	2	no	73.401	72.871	EPSD	COSMIC	72.838	Down-regulation
CMGC_GSK_GSK3A_ST	P10636	MAPT	P49840	GSK3A	S606	S610L	610	Missense	distal	4	no	73.401	67.991	EPSD	COSMIC	72.838	Loss
CMGC_GSK_GSK3A_ST	P10636	MAPT	P49840	GSK3A	S606	D600E	600	Missense	distal	-6	no	73.401	71.767	EPSD	COSMIC	72.838	Loss
CMGC_GSK_GSK3A_ST	P10636	MAPT	P49840	GSK3A	S610	N613D	613	Missense	distal	3	no	79.756	78.943	EPSD	COSMIC	72.838	Down-regulation
CMGC_GSK_GSK3A_ST	P10636	MAPT	P49840	GSK3A	S610	C608W	608	Missense	proximal	-2	no	79.756	79.099	EPSD	COSMIC	72.838	Down-regulation
CMGC_GSK_GSK3A_ST	P10636	MAPT	P49840	GSK3A	S610	S610L	610	Missense	central	0	yes	79.756	0.000	EPSD	COSMIC	72.838	Loss
CMGC_GSK_GSK3A_ST	P10636	MAPT	P49840	GSK3A	S641	H647Y	647	Missense	distal	6	no	77.110	74.894	EPSD	COSMIC	72.838	Down-regulation
CMGC_GSK_GSK3A_ST	P10636	MAPT	P49840	GSK3A	S673	V680I	680	Missense	distal	7	no	81.176	82.179	EPSD	COSMIC	72.838	Up-regulation
CMGC_GSK_GSK3A_ST	P10636	MAPT	P49840	GSK3A	S673	S669L	669	Missense	distal	-4	no	81.176	74.902	EPSD	COSMIC	72.838	Down-regulation
CMGC_GSK_GSK3A_ST	P10636	MAPT	P49840	GSK3A	S673	R666K	666	Missense	distal	-7	no	81.176	82.748	EPSD	COSMIC	72.838	Up-regulation
CMGC_GSK_GSK3A_ST	P10636	MAPT	P49840	GSK3A	S673	S673F	673	Missense	central	0	yes	81.176	0.000	EPSD	COSMIC	72.838	Loss
CMGC_GSK_GSK3A_ST	P10636	MAPT	P49840	GSK3A	S673	K670N	670	Missense	distal	-3	no	81.176	80.986	EPSD	COSMIC	72.838	Down-regulation
CMGC_GSK_GSK3A_ST	P10636	MAPT	P49840	GSK3A	S673	L674Q	674	Missense	proximal	1	no	81.176	84.551	EPSD	COSMIC	72.838	Up-regulation
CMGC_GSK_GSK3A_ST	P10636	MAPT	P49840	GSK3A	S713	E708D	708	Missense	distal	-5	no	88.443	86.131	EPSD	COSMIC	72.838	Down-regulation
CMGC_GSK_GSK3A_ST	P10636	MAPT	P49840	GSK3A	S713	G706R	706	Missense	distal	-7	no	88.443	87.343	EPSD	COSMIC	72.838	Down-regulation
CMGC_GSK_GSK3A_ST	P10636	MAPT	P49840	GSK3A	S713	V710M	710	Missense	distal	-3	no	88.443	88.396	EPSD	COSMIC	72.838	Down-regulation
CMGC_GSK_GSK3A_ST	P10636	MAPT	P49840	GSK3A	S713	E708K	708	Missense	distal	-5	no	88.443	88.333	EPSD	COSMIC	72.838	Down-regulation
CMGC_GSK_GSK3A_ST	P10636	MAPT	P49840	GSK3A	S713	V710A	710	Missense	distal	-3	no	88.443	88.637	EPSD	COSMIC	72.838	Up-regulation
CMGC_GSK_GSK3A_ST	P10636	MAPT	P49840	GSK3A	S717	V710M	710	Missense	distal	-7	no	86.276	85.101	EPSD	COSMIC	72.838	Down-regulation
CMGC_GSK_GSK3A_ST	P10636	MAPT	P49840	GSK3A	S717	R723W	723	Missense	distal	6	no	86.276	78.784	EPSD	COSMIC	72.838	Down-regulation
CMGC_GSK_GSK3A_ST	P10636	MAPT	P49840	GSK3A	S717	V710A	710	Missense	distal	-7	no	86.276	87.151	EPSD	COSMIC	72.838	Up-regulation
CMGC_GSK_GSK3A_ST	P10636	MAPT	P49840	GSK3A	S721	R723W	723	Missense	proximal	2	no	89.833	86.354	EPSD	COSMIC	72.838	Down-regulation
CMGC_GSK_GSK3A_ST	P10636	MAPT	P49840	GSK3A	S721	V728M	728	Missense	distal	7	no	89.833	90.073	EPSD	COSMIC	72.838	Up-regulation
CMGC_GSK_GSK3A_ST	P10636	MAPT	P49840	GSK3A	S721	V728A	728	Missense	distal	7	no	89.833	91.140	EPSD	COSMIC	72.838	Up-regulation
CMGC_GSK_GSK3A_ST	Q14449	GRB14	P49840	GSK3A	S358	Q355P	355	Missense	distal	-3	no	77.640	78.882	EPSD;PhosphoSitePlus	COSMIC	72.838	Up-regulation
CMGC_GSK_GSK3A_ST	Q14449	GRB14	P49840	GSK3A	S362	Q355P	355	Missense	distal	-7	no	81.324	82.172	PhosphoSitePlus;EPSD	COSMIC	72.838	Up-regulation
CMGC_GSK_GSK3A_ST	Q14449	GRB14	P49840	GSK3A	S366	I371V	371	Missense	distal	5	no	87.312	95.535	EPSD;PhosphoSitePlus	COSMIC	72.838	Up-regulation
CMGC_GSK_GSK3A_ST	Q14449	GRB14	P49840	GSK3A	S366	S372P	372	Missense	distal	6	no	87.312	87.862	EPSD;PhosphoSitePlus	COSMIC	72.838	Up-regulation
CMGC_GSK_GSK3A_ST	Q14449	GRB14	P49840	GSK3A	S370	S372P	372	Missense	proximal	2	no	72.741	73.430	EPSD	COSMIC	72.838	Gain
CMGC_GSK_GSK3A_ST	Q14449	GRB14	P49840	GSK3A	S419	R413C	413	Missense	distal	-6	no	86.918	87.126	EPSD;PhosphoSitePlus	COSMIC	72.838	Up-regulation
CMGC_GSK_GSK3A_ST	Q14449	GRB14	P49840	GSK3A	S419	R413L	413	Missense	distal	-6	no	86.918	86.711	EPSD;PhosphoSitePlus	COSMIC	72.838	Down-regulation
CMGC_GSK_GSK3A_ST	Q14449	GRB14	P49840	GSK3A	S419	G418C	418	Missense	proximal	-1	no	86.918	85.977	EPSD;PhosphoSitePlus	COSMIC	72.838	Down-regulation
CMGC_GSK_GSK3A_ST	Q14449	GRB14	P49840	GSK3A	S419	T421P	421	Missense	proximal	2	no	86.918	86.195	EPSD;PhosphoSitePlus	COSMIC	72.838	Down-regulation
CMGC_GSK_GSK3A_ST	Q14449	GRB14	P49840	GSK3A	S423	G418C	418	Missense	distal	-5	no	78.862	76.690	EPSD;PhosphoSitePlus	COSMIC	72.838	Down-regulation
CMGC_GSK_GSK3A_ST	Q14449	GRB14	P49840	GSK3A	S423	T421P	421	Missense	proximal	-2	no	78.862	79.431	EPSD;PhosphoSitePlus	COSMIC	72.838	Up-regulation
CMGC_GSK_GSK3A_ST	Q14449	GRB14	P49840	GSK3A	S424	M431I	431	Missense	distal	7	no	88.602	89.365	EPSD	COSMIC	72.838	Up-regulation
CMGC_GSK_GSK3A_ST	Q14449	GRB14	P49840	GSK3A	S424	G418C	418	Missense	distal	-6	no	88.602	88.968	EPSD	COSMIC	72.838	Up-regulation
CMGC_GSK_GSK3A_ST	Q14449	GRB14	P49840	GSK3A	S424	T421P	421	Missense	distal	-3	no	88.602	88.089	EPSD	COSMIC	72.838	Down-regulation
CMGC_GSK_GSK3A_ST	O75581	LRP6	P49840	GSK3A	S1440	S1447N	1447	Missense	distal	7	no	76.527	75.877	EPSD	COSMIC	72.838	Down-regulation
CMGC_GSK_GSK3A_ST	O75581	LRP6	P49840	GSK3A	S1455	P1459L	1459	Missense	distal	4	no	72.730	73.307	EPSD	COSMIC	72.838	Gain
CMGC_GSK_GSK3A_ST	O75581	LRP6	P49840	GSK3A	S1470	A1463V	1463	Missense	distal	-7	no	77.308	76.434	EPSD	COSMIC;GDSC;CCLE	72.838	Down-regulation
CMGC_GSK_GSK3A_ST	O75581	LRP6	P49840	GSK3A	S1470	H1464Y	1464	Missense	distal	-6	no	77.308	77.111	EPSD	COSMIC	72.838	Down-regulation
CMGC_GSK_GSK3A_ST	O75581	LRP6	P49840	GSK3A	S1470	S1469A	1469	Missense	proximal	-1	no	77.308	78.081	EPSD	COSMIC	72.838	Up-regulation
CMGC_GSK_GSK3A_ST	O75581	LRP6	P49840	GSK3A	S1472	S1469A	1469	Missense	distal	-3	no	72.983	73.308	EPSD	COSMIC	72.838	Up-regulation
CMGC_GSK_GSK3A_ST	O75581	LRP6	P49840	GSK3A	S1473	S1469A	1469	Missense	distal	-4	no	81.508	76.561	EPSD	COSMIC	72.838	Down-regulation
CMGC_GSK_GSK3A_ST	O75581	LRP6	P49840	GSK3A	S1490	S1490F	1490	Missense	central	0	yes	88.879	0.000	EPSD	COSMIC	72.838	Loss
CMGC_GSK_GSK3A_ST	O75581	LRP6	P49840	GSK3A	S1490	S1496L	1496	Missense	distal	6	no	88.879	86.549	EPSD	COSMIC	72.838	Down-regulation
CMGC_GSK_GSK3A_ST	O75581	LRP6	P49840	GSK3A	S1510	S1508R	1508	Missense	proximal	-2	no	74.967	75.330	EPSD	COSMIC	72.838	Up-regulation
CMGC_GSK_GSK3A_ST	O75581	LRP6	P49840	GSK3A	S1510	S1514A	1514	Missense	distal	4	no	74.967	71.881	EPSD	COSMIC	72.838	Loss
CMGC_GSK_GSK3A_ST	O75581	LRP6	P49840	GSK3A	S1510	N1507K	1507	Missense	distal	-3	no	74.967	75.157	EPSD	COSMIC	72.838	Up-regulation
CMGC_GSK_GSK3A_ST	O75581	LRP6	P49840	GSK3A	S1516	Y1520C	1520	Missense	distal	4	no	80.230	12.439	EPSD	COSMIC	72.838	Loss
CMGC_GSK_GSK3A_ST	O75581	LRP6	P49840	GSK3A	S1516	S1514A	1514	Missense	proximal	-2	no	80.230	79.927	EPSD	COSMIC	72.838	Down-regulation
CMGC_GSK_GSK3A_ST	O75581	LRP6	P49840	GSK3A	S1516	R1523Q	1523	Missense	distal	7	no	80.230	80.734	EPSD	COSMIC;GDSC	72.838	Up-regulation
CMGC_GSK_GSK3A_ST	O75581	LRP6	P49840	GSK3A	S1521	P1528H	1528	Missense	distal	7	no	74.896	74.492	EPSD	COSMIC	72.838	Down-regulation
CMGC_GSK_GSK3A_ST	O75581	LRP6	P49840	GSK3A	S1521	Y1520C	1520	Missense	proximal	-1	no	74.896	72.610	EPSD	COSMIC	72.838	Loss
CMGC_GSK_GSK3A_ST	O75581	LRP6	P49840	GSK3A	S1521	S1514A	1514	Missense	distal	-7	no	74.896	75.855	EPSD	COSMIC	72.838	Up-regulation
CMGC_GSK_GSK3A_ST	O75581	LRP6	P49840	GSK3A	S1521	R1523Q	1523	Missense	proximal	2	no	74.896	74.298	EPSD	COSMIC;GDSC	72.838	Down-regulation
CMGC_GSK_GSK3A_ST	O75581	LRP6	P49840	GSK3A	T1530	P1528H	1528	Missense	proximal	-2	no	83.729	83.476	EPSD	COSMIC	72.838	Down-regulation
CMGC_GSK_GSK3A_ST	O75581	LRP6	P49840	GSK3A	T1530	R1523Q	1523	Missense	distal	-7	no	83.729	83.941	EPSD	COSMIC;GDSC	72.838	Up-regulation
CMGC_GSK_GSK3A_ST	O75581	LRP6	P49840	GSK3A	S1544	R1545L	1545	Missense	proximal	1	no	87.483	82.084	PhosphoSitePlus	COSMIC	72.838	Down-regulation
CMGC_GSK_GSK3A_ST	O75581	LRP6	P49840	GSK3A	S1544	A1542G	1542	Missense	proximal	-2	no	87.483	87.046	PhosphoSitePlus	COSMIC	72.838	Down-regulation
CMGC_GSK_GSK3A_ST	O75581	LRP6	P49840	GSK3A	S1544	P1543S	1543	Missense	proximal	-1	no	87.483	86.586	PhosphoSitePlus	COSMIC	72.838	Down-regulation
CMGC_GSK_GSK3A_ST	O75581	LRP6	P49840	GSK3A	T1548	R1545L	1545	Missense	distal	-3	no	76.065	75.213	EPSD	COSMIC	72.838	Down-regulation
CMGC_GSK_GSK3A_ST	O75581	LRP6	P49840	GSK3A	T1548	A1542G	1542	Missense	distal	-6	no	76.065	75.585	EPSD	COSMIC	72.838	Down-regulation
CMGC_GSK_GSK3A_ST	O75581	LRP6	P49840	GSK3A	T1548	P1543S	1543	Missense	distal	-5	no	76.065	76.151	EPSD	COSMIC	72.838	Up-regulation
CMGC_GSK_GSK3A_ST	O75581	LRP6	P49840	GSK3A	S1579	E1581Q	1581	Missense	proximal	2	no	82.420	81.422	EPSD	COSMIC	72.838	Down-regulation
CMGC_GSK_GSK3A_ST	O75581	LRP6	P49840	GSK3A	S1586	P1589R	1589	Missense	distal	3	no	78.359	77.312	EPSD	COSMIC	72.838	Down-regulation
CMGC_GSK_GSK3A_ST	O75581	LRP6	P49840	GSK3A	S1586	E1581Q	1581	Missense	distal	-5	no	78.359	79.829	EPSD	COSMIC	72.838	Up-regulation
CMGC_GSK_GSK3A_ST	O75581	LRP6	P49840	GSK3A	S1590	P1589R	1589	Missense	proximal	-1	no	84.387	83.191	EPSD	COSMIC	72.838	Down-regulation
CMGC_GSK_GSK3A_ST	O75581	LRP6	P49840	GSK3A	T1593	P1589R	1589	Missense	distal	-4	no	73.183	73.401	EPSD	COSMIC	72.838	Up-regulation
CMGC_GSK_GSK3A_ST	O75581	LRP6	P49840	GSK3A	T1593	H1600Q	1600	Missense	distal	7	no	73.183	73.214	EPSD	COSMIC	72.838	Up-regulation
CMGC_GSK_GSK3A_ST	Q8NHW3	MAFA	P49840	GSK3A	T134	N127K	127	Missense	distal	-7	no	74.776	75.158	EPSD	COSMIC	72.838	Up-regulation
CMGC_GSK_GSK3A_ST	Q14596	NBR1	P49840	GSK3A	S276	F270L	270	Missense	distal	-6	no	81.543	80.093	EPSD	COSMIC	72.838	Down-regulation
CMGC_GSK_GSK3A_ST	Q14596	NBR1	P49840	GSK3A	S276	K274E	274	Missense	proximal	-2	no	81.543	80.182	EPSD	COSMIC	72.838	Down-regulation
CMGC_GSK_GSK3A_ST	Q14596	NBR1	P49840	GSK3A	S340	R347Q	347	Missense	distal	7	no	77.016	77.520	EPSD	COSMIC;GDSC;CCLE	72.838	Up-regulation
CMGC_GSK_GSK3A_ST	Q14596	NBR1	P49840	GSK3A	S340	G346D	346	Missense	distal	6	no	77.016	77.731	EPSD	COSMIC	72.838	Up-regulation
CMGC_GSK_GSK3A_ST	Q14596	NBR1	P49840	GSK3A	S833	H829R	829	Missense	distal	-4	no	80.995	78.031	EPSD	COSMIC	72.838	Down-regulation
CMGC_GSK_GSK3A_ST	Q14596	NBR1	P49840	GSK3A	S833	P834S	834	Missense	proximal	1	no	80.995	65.303	EPSD	COSMIC;GDSC;CCLE	72.838	Loss
CMGC_GSK_GSK3A_ST	Q14596	NBR1	P49840	GSK3A	S833	S833F	833	Missense	central	0	yes	80.995	0.000	EPSD	COSMIC	72.838	Loss
CMGC_GSK_GSK3A_ST	P20749	BCL3	P49840	GSK3A	S122	C115Y	115	Missense	distal	-7	no	79.588	81.912	EPSD	COSMIC	72.838	Up-regulation
CMGC_GSK_GSK3A_ST	P20749	BCL3	P49840	GSK3A	T363	K361E	361	Missense	proximal	-2	no	81.408	80.046	EPSD	COSMIC	72.838	Down-regulation
CMGC_GSK_GSK3A_ST	P20749	BCL3	P49840	GSK3A	S367	K361E	361	Missense	distal	-6	no	83.205	83.000	EPSD	COSMIC	72.838	Down-regulation
CMGC_GSK_GSK3A_ST	P20749	BCL3	P49840	GSK3A	S369	P375S	375	Missense	distal	6	no	75.204	74.655	EPSD	COSMIC	72.838	Down-regulation
CMGC_GSK_GSK3A_ST	P20749	BCL3	P49840	GSK3A	S374	T381S	381	Missense	distal	7	no	88.220	87.632	EPSD	COSMIC	72.838	Down-regulation
CMGC_GSK_GSK3A_ST	P20749	BCL3	P49840	GSK3A	S374	P375S	375	Missense	proximal	1	no	88.220	72.528	EPSD	COSMIC	72.838	Loss
CMGC_GSK_GSK3A_ST	P20749	BCL3	P49840	GSK3A	S374	R377Q	377	Missense	distal	3	no	88.220	86.386	EPSD	COSMIC	72.838	Down-regulation
CMGC_GSK_GSK3A_ST	P20749	BCL3	P49840	GSK3A	S378	T381S	381	Missense	distal	3	no	85.952	83.929	EPSD	COSMIC	72.838	Down-regulation
CMGC_GSK_GSK3A_ST	P20749	BCL3	P49840	GSK3A	S378	P375S	375	Missense	distal	-3	no	85.952	85.312	EPSD	COSMIC	72.838	Down-regulation
CMGC_GSK_GSK3A_ST	P20749	BCL3	P49840	GSK3A	S378	R377Q	377	Missense	proximal	-1	no	85.952	87.125	EPSD	COSMIC	72.838	Up-regulation
CMGC_GSK_GSK3A_ST	P20749	BCL3	P49840	GSK3A	S378	P383H	383	Missense	distal	5	no	85.952	74.312	EPSD	COSMIC	72.838	Down-regulation
CMGC_GSK_GSK3A_ST	P20749	BCL3	P49840	GSK3A	S382	R388G	388	Missense	distal	6	no	92.236	89.877	EPSD	COSMIC	72.838	Down-regulation
CMGC_GSK_GSK3A_ST	P20749	BCL3	P49840	GSK3A	S382	T381S	381	Missense	proximal	-1	no	92.236	90.553	EPSD	COSMIC	72.838	Down-regulation
CMGC_GSK_GSK3A_ST	P20749	BCL3	P49840	GSK3A	S382	P375S	375	Missense	distal	-7	no	92.236	92.081	EPSD	COSMIC	72.838	Down-regulation
CMGC_GSK_GSK3A_ST	P20749	BCL3	P49840	GSK3A	S382	R377Q	377	Missense	distal	-5	no	92.236	94.585	EPSD	COSMIC	72.838	Up-regulation
CMGC_GSK_GSK3A_ST	P20749	BCL3	P49840	GSK3A	S382	P383H	383	Missense	proximal	1	no	92.236	65.822	EPSD	COSMIC	72.838	Loss
CMGC_GSK_GSK3A_ST	P20749	BCL3	P49840	GSK3A	S402	P399T	399	Missense	distal	-3	no	97.336	97.849	PhosphoSitePlus;EPSD	COSMIC	72.838	Up-regulation
CMGC_GSK_GSK3A_ST	P20749	BCL3	P49840	GSK3A	S402	P407R	407	Missense	distal	5	no	97.336	92.191	PhosphoSitePlus;EPSD	COSMIC;GDSC;CCLE	72.838	Down-regulation
CMGC_GSK_GSK3A_ST	P20749	BCL3	P49840	GSK3A	S402	P408S	408	Missense	distal	6	no	97.336	96.786	PhosphoSitePlus;EPSD	COSMIC	72.838	Down-regulation
CMGC_GSK_GSK3A_ST	P20749	BCL3	P49840	GSK3A	S406	P411L	411	Missense	distal	5	no	104.218	95.044	EPSD;PhosphoSitePlus	COSMIC	72.838	Down-regulation
CMGC_GSK_GSK3A_ST	P20749	BCL3	P49840	GSK3A	S406	D410G	410	Missense	distal	4	no	104.218	91.022	EPSD;PhosphoSitePlus	COSMIC	72.838	Down-regulation
CMGC_GSK_GSK3A_ST	P20749	BCL3	P49840	GSK3A	S406	P399T	399	Missense	distal	-7	no	104.218	104.911	EPSD;PhosphoSitePlus	COSMIC	72.838	Up-regulation
CMGC_GSK_GSK3A_ST	P20749	BCL3	P49840	GSK3A	S406	P407R	407	Missense	proximal	1	no	104.218	95.565	EPSD;PhosphoSitePlus	COSMIC;GDSC;CCLE	72.838	Down-regulation
CMGC_GSK_GSK3A_ST	P20749	BCL3	P49840	GSK3A	S406	P408S	408	Missense	proximal	2	no	104.218	103.529	EPSD;PhosphoSitePlus	COSMIC	72.838	Down-regulation
CMGC_GSK_GSK3A_ST	P49840	GSK3A	P49840	GSK3A	S97	V104I	104	Missense	distal	7	no	77.022	78.025	EPSD	COSMIC;GDSC;CCLE	72.838	Up-regulation
CMGC_GSK_GSK3A_ST	P49840	GSK3A	P49840	GSK3A	S282	Y285C	285	Missense	distal	3	no	74.809	66.599	EPSD	COSMIC	72.838	Loss
CMGC_GSK_GSK3A_ST	P22415	USF1	P49840	GSK3A	T153	P154A	154	Missense	proximal	1	no	90.075	76.408	EPSD;PhosphoSitePlus	COSMIC	72.838	Down-regulation
CMGC_GSK_GSK3A_ST	P22415	USF1	P49840	GSK3A	T153	G150W	150	Missense	distal	-3	no	90.075	89.040	EPSD;PhosphoSitePlus	COSMIC;GDSC;CCLE	72.838	Down-regulation
CMGC_GSK_GSK3A_ST	P22415	USF1	P49840	GSK3A	T153	P155T	155	Missense	proximal	2	no	90.075	90.798	EPSD;PhosphoSitePlus	COSMIC	72.838	Up-regulation
CMGC_GSK_GSK3A_ST	P22415	USF1	P49840	GSK3A	S186	R181S	181	Missense	distal	-5	no	92.592	94.266	PhosphoSitePlus;EPSD	COSMIC	72.838	Up-regulation
CMGC_GSK_GSK3A_ST	P22415	USF1	P49840	GSK3A	S186	T182I	182	Missense	distal	-4	no	92.592	85.999	PhosphoSitePlus;EPSD	COSMIC	72.838	Down-regulation
CMGC_GSK_GSK3A_ST	P22415	USF1	P49840	GSK3A	S186	A191S	191	Missense	distal	5	no	92.592	93.511	PhosphoSitePlus;EPSD	COSMIC	72.838	Up-regulation
CMGC_GSK_GSK3A_ST	P22415	USF1	P49840	GSK3A	S186	R193W	193	Missense	distal	7	no	92.592	92.590	PhosphoSitePlus;EPSD	COSMIC	72.838	Down-regulation
CMGC_GSK_GSK3A_ST	P22415	USF1	P49840	GSK3A	S186	P187T	187	Missense	proximal	1	no	92.592	77.941	PhosphoSitePlus;EPSD	COSMIC	72.838	Down-regulation
CMGC_GSK_GSK3A_ST	P22415	USF1	P49840	GSK3A	S186	Y185H	185	Missense	proximal	-1	no	92.592	91.422	PhosphoSitePlus;EPSD	COSMIC	72.838	Down-regulation
CMGC_GSK_GSK3A_ST	P22415	USF1	P49840	GSK3A	S186	P192A	192	Missense	distal	6	no	92.592	90.047	PhosphoSitePlus;EPSD	COSMIC	72.838	Down-regulation
CMGC_GSK_GSK3A_ST	P22415	USF1	P49840	GSK3A	S186	P184A	184	Missense	proximal	-2	no	92.592	92.138	PhosphoSitePlus;EPSD	COSMIC	72.838	Down-regulation
CMGC_GSK_GSK3A_ST	P22415	USF1	P49840	GSK3A	T195	E198K	198	Missense	distal	3	no	79.029	79.533	EPSD	COSMIC	72.838	Up-regulation
CMGC_GSK_GSK3A_ST	P22415	USF1	P49840	GSK3A	T195	A202T	202	Missense	distal	7	no	79.029	79.417	EPSD	COSMIC	72.838	Up-regulation
CMGC_GSK_GSK3A_ST	P22415	USF1	P49840	GSK3A	T195	A191S	191	Missense	distal	-4	no	79.029	83.975	EPSD	COSMIC	72.838	Up-regulation
CMGC_GSK_GSK3A_ST	P22415	USF1	P49840	GSK3A	T195	R193W	193	Missense	proximal	-2	no	79.029	76.867	EPSD	COSMIC	72.838	Down-regulation
CMGC_GSK_GSK3A_ST	P22415	USF1	P49840	GSK3A	T195	P192A	192	Missense	distal	-3	no	79.029	78.714	EPSD	COSMIC	72.838	Down-regulation
CMGC_GSK_GSK3A_ST	Q96F46	IL17RA	P49840	GSK3A	S726	P733L	733	Missense	distal	7	no	83.451	82.487	EPSD	COSMIC	72.838	Down-regulation
CMGC_GSK_GSK3A_ST	Q96F46	IL17RA	P49840	GSK3A	T732	P733L	733	Missense	proximal	1	no	80.376	66.324	EPSD	COSMIC	72.838	Loss
CMGC_GSK_GSK3A_ST	Q96F46	IL17RA	P49840	GSK3A	T732	L739I	739	Missense	distal	7	no	80.376	80.892	EPSD	COSMIC	72.838	Up-regulation
CMGC_GSK_GSK3A_ST	Q96F46	IL17RA	P49840	GSK3A	S736	P733L	733	Missense	distal	-3	no	74.091	72.347	EPSD	COSMIC	72.838	Loss
CMGC_GSK_GSK3A_ST	Q96F46	IL17RA	P49840	GSK3A	S736	L740F	740	Missense	distal	4	no	74.091	57.210	EPSD	COSMIC	72.838	Loss
CMGC_GSK_GSK3A_ST	Q96F46	IL17RA	P49840	GSK3A	S736	L739I	739	Missense	distal	3	no	74.091	75.918	EPSD	COSMIC	72.838	Up-regulation
CMGC_GSK_GSK3A_ST	Q96F46	IL17RA	P49840	GSK3A	T780	E784A	784	Missense	distal	4	no	90.191	91.065	PhosphoSitePlus	COSMIC	72.838	Up-regulation
CMGC_GSK_GSK3A_ST	Q96F46	IL17RA	P49840	GSK3A	S801	S800C	800	Missense	proximal	-1	no	81.014	80.048	EPSD	COSMIC	72.838	Down-regulation
CMGC_GSK_GSK3A_ST	Q96F46	IL17RA	P49840	GSK3A	S801	P802S	802	Missense	proximal	1	no	81.014	65.322	EPSD	COSMIC;GDSC;CCLE	72.838	Loss
CMGC_GSK_GSK3A_ST	Q96F46	IL17RA	P49840	GSK3A	S829	A825V	825	Missense	distal	-4	no	79.854	79.024	EPSD	COSMIC	72.838	Down-regulation
CMGC_GSK_GSK3A_ST	P17661	DES	P49840	GSK3A	S32	A38T	38	Missense	distal	6	no	86.250	88.976	PhosphoSitePlus;EPSD	COSMIC	72.838	Up-regulation
CMGC_GSK_GSK3A_ST	P17661	DES	P49840	GSK3A	S46	G41S	41	Missense	distal	-5	no	72.830	73.014	EPSD	COSMIC	72.838	Gain
CMGC_GSK_GSK3A_ST	P17661	DES	P49840	GSK3A	S68	G62R	62	Missense	distal	-6	no	86.365	86.523	EPSD	COSMIC	72.838	Up-regulation
CMGC_GSK_GSK3A_ST	P17661	DES	P49840	GSK3A	S68	G65S	65	Missense	distal	-3	no	86.365	86.784	EPSD	COSMIC;GDSC;CCLE	72.838	Up-regulation
CMGC_GSK_GSK3A_ST	P17661	DES	P49840	GSK3A	S68	G64R	64	Missense	distal	-4	no	86.365	87.834	EPSD	COSMIC;CCLE	72.838	Up-regulation
CMGC_GSK_GSK3A_ST	P17661	DES	P49840	GSK3A	S68	G65D	65	Missense	distal	-3	no	86.365	86.155	EPSD	COSMIC	72.838	Down-regulation
CMGC_GSK_GSK3A_ST	P17661	DES	P49840	GSK3A	S72	G65S	65	Missense	distal	-7	no	102.399	102.205	EPSD	COSMIC;GDSC;CCLE	72.838	Down-regulation
CMGC_GSK_GSK3A_ST	P17661	DES	P49840	GSK3A	S72	G65D	65	Missense	distal	-7	no	102.399	100.788	EPSD	COSMIC	72.838	Down-regulation
CMGC_GSK_GSK3A_ST	P17661	DES	P49840	GSK3A	S330	R325Q	325	Missense	distal	-5	no	70.571	72.920	EPSD	COSMIC	72.838	Gain
CMGC_GSK_GSK3A_ST	P17661	DES	P49840	GSK3A	S344	Q348K	348	Missense	distal	4	no	65.183	76.582	EPSD	COSMIC	72.838	Gain
CMGC_GSK_GSK3A_ST	P17661	DES	P49840	GSK3A	S414	I420T	420	Missense	distal	6	no	70.795	73.223	EPSD	COSMIC	72.838	Gain
CMGC_GSK_GSK3A_ST	P35222	CTNNB1	P49840	GSK3A	S29	W25R	25	Missense	distal	-4	no	69.608	75.219	EPSD	COSMIC	72.838	Gain
CMGC_GSK_GSK3A_ST	P35222	CTNNB1	P49840	GSK3A	S33	A39G	39	Missense	distal	6	no	93.350	94.392	EPSD;PhosphoSitePlus	COSMIC	72.838	Up-regulation
CMGC_GSK_GSK3A_ST	P35222	CTNNB1	P49840	GSK3A	S33	G38A	38	Missense	distal	5	no	93.350	92.465	EPSD;PhosphoSitePlus	COSMIC	72.838	Down-regulation
CMGC_GSK_GSK3A_ST	P35222	CTNNB1	P49840	GSK3A	S33	T40I	40	Missense	distal	7	no	93.350	92.657	EPSD;PhosphoSitePlus	COSMIC	72.838	Down-regulation
CMGC_GSK_GSK3A_ST	P35222	CTNNB1	P49840	GSK3A	S33	I35T	35	Missense	proximal	2	no	93.350	97.130	EPSD;PhosphoSitePlus	COSMIC	72.838	Up-regulation
CMGC_GSK_GSK3A_ST	P35222	CTNNB1	P49840	GSK3A	S33	Q28E	28	Missense	distal	-5	no	93.350	91.880	EPSD;PhosphoSitePlus	COSMIC	72.838	Down-regulation
CMGC_GSK_GSK3A_ST	P35222	CTNNB1	P49840	GSK3A	S33	D32E	32	Missense	proximal	-1	no	93.350	95.039	EPSD;PhosphoSitePlus	COSMIC	72.838	Up-regulation
CMGC_GSK_GSK3A_ST	P35222	CTNNB1	P49840	GSK3A	S33	H36R	36	Missense	distal	3	no	93.350	89.339	EPSD;PhosphoSitePlus	COSMIC	72.838	Down-regulation
CMGC_GSK_GSK3A_ST	P35222	CTNNB1	P49840	GSK3A	S33	T40A	40	Missense	distal	7	no	93.350	92.962	EPSD;PhosphoSitePlus	COSMIC	72.838	Down-regulation
CMGC_GSK_GSK3A_ST	P35222	CTNNB1	P49840	GSK3A	S33	G34L	34	Missense	proximal	1	no	93.350	89.774	EPSD;PhosphoSitePlus	COSMIC	72.838	Down-regulation
CMGC_GSK_GSK3A_ST	P35222	CTNNB1	P49840	GSK3A	S33	S33L	33	Missense	central	0	yes	93.350	0.000	EPSD;PhosphoSitePlus	COSMIC;CCLE	72.838	Loss
CMGC_GSK_GSK3A_ST	P35222	CTNNB1	P49840	GSK3A	S33	S29P	29	Missense	distal	-4	no	93.350	89.764	EPSD;PhosphoSitePlus	COSMIC	72.838	Down-regulation
CMGC_GSK_GSK3A_ST	P35222	CTNNB1	P49840	GSK3A	S33	L31P	31	Missense	proximal	-2	no	93.350	94.218	EPSD;PhosphoSitePlus	COSMIC	72.838	Up-regulation
CMGC_GSK_GSK3A_ST	P35222	CTNNB1	P49840	GSK3A	S33	S37L	37	Missense	distal	4	no	93.350	87.941	EPSD;PhosphoSitePlus	COSMIC	72.838	Down-regulation
CMGC_GSK_GSK3A_ST	P35222	CTNNB1	P49840	GSK3A	S33	A39T	39	Missense	distal	6	no	93.350	96.077	EPSD;PhosphoSitePlus	COSMIC	72.838	Up-regulation
CMGC_GSK_GSK3A_ST	P35222	CTNNB1	P49840	GSK3A	S33	Q27H	27	Missense	distal	-6	no	93.350	93.468	EPSD;PhosphoSitePlus	COSMIC	72.838	Up-regulation
CMGC_GSK_GSK3A_ST	P35222	CTNNB1	P49840	GSK3A	S33	S33N	33	Missense	central	0	yes	93.350	0.000	EPSD;PhosphoSitePlus	COSMIC	72.838	Loss
CMGC_GSK_GSK3A_ST	P35222	CTNNB1	P49840	GSK3A	S33	H36Y	36	Missense	distal	3	no	93.350	92.949	EPSD;PhosphoSitePlus	COSMIC	72.838	Down-regulation
CMGC_GSK_GSK3A_ST	P35222	CTNNB1	P49840	GSK3A	S33	S29F	29	Missense	distal	-4	no	93.350	85.592	EPSD;PhosphoSitePlus	COSMIC	72.838	Down-regulation
CMGC_GSK_GSK3A_ST	P35222	CTNNB1	P49840	GSK3A	S33	Y30C	30	Missense	distal	-3	no	93.350	91.604	EPSD;PhosphoSitePlus	COSMIC	72.838	Down-regulation
CMGC_GSK_GSK3A_ST	P35222	CTNNB1	P49840	GSK3A	S33	S29Y	29	Missense	distal	-4	no	93.350	92.470	EPSD;PhosphoSitePlus	COSMIC	72.838	Down-regulation
CMGC_GSK_GSK3A_ST	P35222	CTNNB1	P49840	GSK3A	S33	G38P	38	Missense	distal	5	no	93.350	98.941	EPSD;PhosphoSitePlus	COSMIC	72.838	Up-regulation
CMGC_GSK_GSK3A_ST	P35222	CTNNB1	P49840	GSK3A	S33	G38D	38	Missense	distal	5	no	93.350	92.072	EPSD;PhosphoSitePlus	COSMIC	72.838	Down-regulation
CMGC_GSK_GSK3A_ST	P35222	CTNNB1	P49840	GSK3A	S33	I35M	35	Missense	proximal	2	no	93.350	95.904	EPSD;PhosphoSitePlus	COSMIC	72.838	Up-regulation
CMGC_GSK_GSK3A_ST	P35222	CTNNB1	P49840	GSK3A	S33	T40S	40	Missense	distal	7	no	93.350	92.763	EPSD;PhosphoSitePlus	COSMIC	72.838	Down-regulation
CMGC_GSK_GSK3A_ST	P35222	CTNNB1	P49840	GSK3A	S33	S29A	29	Missense	distal	-4	no	93.350	88.404	EPSD;PhosphoSitePlus	COSMIC	72.838	Down-regulation
CMGC_GSK_GSK3A_ST	P35222	CTNNB1	P49840	GSK3A	S33	G34A	34	Missense	proximal	1	no	93.350	90.159	EPSD;PhosphoSitePlus	COSMIC	72.838	Down-regulation
CMGC_GSK_GSK3A_ST	P35222	CTNNB1	P49840	GSK3A	S33	L31W	31	Missense	proximal	-2	no	93.350	92.267	EPSD;PhosphoSitePlus	COSMIC	72.838	Down-regulation
CMGC_GSK_GSK3A_ST	P35222	CTNNB1	P49840	GSK3A	S33	G34I	34	Missense	proximal	1	no	93.350	83.404	EPSD;PhosphoSitePlus	COSMIC	72.838	Down-regulation
CMGC_GSK_GSK3A_ST	P35222	CTNNB1	P49840	GSK3A	S33	I35N	35	Missense	proximal	2	no	93.350	93.157	EPSD;PhosphoSitePlus	COSMIC	72.838	Down-regulation
CMGC_GSK_GSK3A_ST	P35222	CTNNB1	P49840	GSK3A	S33	D32C	32	Missense	proximal	-1	no	93.350	93.026	EPSD;PhosphoSitePlus	COSMIC	72.838	Down-regulation
CMGC_GSK_GSK3A_ST	P35222	CTNNB1	P49840	GSK3A	S33	Y30S	30	Missense	distal	-3	no	93.350	92.491	EPSD;PhosphoSitePlus	COSMIC	72.838	Down-regulation
CMGC_GSK_GSK3A_ST	P35222	CTNNB1	P49840	GSK3A	S33	L31M	31	Missense	proximal	-2	no	93.350	93.185	EPSD;PhosphoSitePlus	COSMIC	72.838	Down-regulation
CMGC_GSK_GSK3A_ST	P35222	CTNNB1	P49840	GSK3A	S33	A39V	39	Missense	distal	6	no	93.350	91.733	EPSD;PhosphoSitePlus	COSMIC	72.838	Down-regulation
CMGC_GSK_GSK3A_ST	P35222	CTNNB1	P49840	GSK3A	S33	L31Q	31	Missense	proximal	-2	no	93.350	94.094	EPSD;PhosphoSitePlus	COSMIC	72.838	Up-regulation
CMGC_GSK_GSK3A_ST	P35222	CTNNB1	P49840	GSK3A	S33	G34D	34	Missense	proximal	1	no	93.350	83.181	EPSD;PhosphoSitePlus	COSMIC	72.838	Down-regulation
CMGC_GSK_GSK3A_ST	P35222	CTNNB1	P49840	GSK3A	S33	Q26R	26	Missense	distal	-7	no	93.350	93.138	EPSD;PhosphoSitePlus	COSMIC;GDSC;CCLE	72.838	Down-regulation
CMGC_GSK_GSK3A_ST	P35222	CTNNB1	P49840	GSK3A	S33	S37T	37	Missense	distal	4	no	93.350	92.850	EPSD;PhosphoSitePlus	COSMIC	72.838	Down-regulation
CMGC_GSK_GSK3A_ST	P35222	CTNNB1	P49840	GSK3A	S33	I35K	35	Missense	proximal	2	no	93.350	97.243	EPSD;PhosphoSitePlus	COSMIC	72.838	Up-regulation
CMGC_GSK_GSK3A_ST	P35222	CTNNB1	P49840	GSK3A	S33	Q28R	28	Missense	distal	-5	no	93.350	91.001	EPSD;PhosphoSitePlus	COSMIC	72.838	Down-regulation
CMGC_GSK_GSK3A_ST	P35222	CTNNB1	P49840	GSK3A	S33	D32F	32	Missense	proximal	-1	no	93.350	91.641	EPSD;PhosphoSitePlus	COSMIC	72.838	Down-regulation
CMGC_GSK_GSK3A_ST	P35222	CTNNB1	P49840	GSK3A	S33	G38X	38	Missense	distal	5	no	93.350	85.153	EPSD;PhosphoSitePlus	COSMIC	72.838	Down-regulation
CMGC_GSK_GSK3A_ST	P35222	CTNNB1	P49840	GSK3A	S33	D32X	32	Missense	proximal	-1	no	93.350	93.489	EPSD;PhosphoSitePlus	COSMIC	72.838	Up-regulation
CMGC_GSK_GSK3A_ST	P35222	CTNNB1	P49840	GSK3A	S33	S33K	33	Missense	central	0	yes	93.350	0.000	EPSD;PhosphoSitePlus	COSMIC	72.838	Loss
CMGC_GSK_GSK3A_ST	P35222	CTNNB1	P49840	GSK3A	S33	I35V	35	Missense	proximal	2	no	93.350	94.637	EPSD;PhosphoSitePlus	COSMIC	72.838	Up-regulation
CMGC_GSK_GSK3A_ST	P35222	CTNNB1	P49840	GSK3A	S33	S29T	29	Missense	distal	-4	no	93.350	94.159	EPSD;PhosphoSitePlus	COSMIC	72.838	Up-regulation
CMGC_GSK_GSK3A_ST	P35222	CTNNB1	P49840	GSK3A	S33	G34C	34	Missense	proximal	1	no	93.350	76.784	EPSD;PhosphoSitePlus	COSMIC	72.838	Down-regulation
CMGC_GSK_GSK3A_ST	P35222	CTNNB1	P49840	GSK3A	S33	G38S	38	Missense	distal	5	no	93.350	93.384	EPSD;PhosphoSitePlus	COSMIC	72.838	Up-regulation
CMGC_GSK_GSK3A_ST	P35222	CTNNB1	P49840	GSK3A	S33	S37V	37	Missense	distal	4	no	93.350	87.771	EPSD;PhosphoSitePlus	COSMIC	72.838	Down-regulation
CMGC_GSK_GSK3A_ST	P35222	CTNNB1	P49840	GSK3A	S33	I35F	35	Missense	proximal	2	no	93.350	92.125	EPSD;PhosphoSitePlus	COSMIC	72.838	Down-regulation
CMGC_GSK_GSK3A_ST	P35222	CTNNB1	P49840	GSK3A	S33	T40P	40	Missense	distal	7	no	93.350	93.104	EPSD;PhosphoSitePlus	COSMIC	72.838	Down-regulation
CMGC_GSK_GSK3A_ST	P35222	CTNNB1	P49840	GSK3A	S37	P44S	44	Missense	distal	7	no	82.758	82.417	PhosphoSitePlus;EPSD	COSMIC	72.838	Down-regulation
CMGC_GSK_GSK3A_ST	P35222	CTNNB1	P49840	GSK3A	S37	A43V	43	Missense	distal	6	no	82.758	81.140	PhosphoSitePlus;EPSD	COSMIC	72.838	Down-regulation
CMGC_GSK_GSK3A_ST	P35222	CTNNB1	P49840	GSK3A	S37	A39G	39	Missense	proximal	2	no	82.758	81.590	PhosphoSitePlus;EPSD	COSMIC	72.838	Down-regulation
CMGC_GSK_GSK3A_ST	P35222	CTNNB1	P49840	GSK3A	S37	G38A	38	Missense	proximal	1	no	82.758	79.567	PhosphoSitePlus;EPSD	COSMIC	72.838	Down-regulation
CMGC_GSK_GSK3A_ST	P35222	CTNNB1	P49840	GSK3A	S37	T40I	40	Missense	distal	3	no	82.758	80.034	PhosphoSitePlus;EPSD	COSMIC	72.838	Down-regulation
CMGC_GSK_GSK3A_ST	P35222	CTNNB1	P49840	GSK3A	S37	P44A	44	Missense	distal	7	no	82.758	82.616	PhosphoSitePlus;EPSD	COSMIC	72.838	Down-regulation
CMGC_GSK_GSK3A_ST	P35222	CTNNB1	P49840	GSK3A	S37	I35T	35	Missense	proximal	-2	no	82.758	83.225	PhosphoSitePlus;EPSD	COSMIC	72.838	Up-regulation
CMGC_GSK_GSK3A_ST	P35222	CTNNB1	P49840	GSK3A	S37	T41P	41	Missense	distal	4	no	82.758	77.272	PhosphoSitePlus;EPSD	COSMIC	72.838	Down-regulation
CMGC_GSK_GSK3A_ST	P35222	CTNNB1	P49840	GSK3A	S37	T42R	42	Missense	distal	5	no	82.758	82.494	PhosphoSitePlus;EPSD	COSMIC	72.838	Down-regulation
CMGC_GSK_GSK3A_ST	P35222	CTNNB1	P49840	GSK3A	S37	D32E	32	Missense	distal	-5	no	82.758	85.071	PhosphoSitePlus;EPSD	COSMIC	72.838	Up-regulation
CMGC_GSK_GSK3A_ST	P35222	CTNNB1	P49840	GSK3A	S37	H36R	36	Missense	proximal	-1	no	82.758	82.310	PhosphoSitePlus;EPSD	COSMIC	72.838	Down-regulation
CMGC_GSK_GSK3A_ST	P35222	CTNNB1	P49840	GSK3A	S37	T40A	40	Missense	distal	3	no	82.758	81.378	PhosphoSitePlus;EPSD	COSMIC	72.838	Down-regulation
CMGC_GSK_GSK3A_ST	P35222	CTNNB1	P49840	GSK3A	S37	A43T	43	Missense	distal	6	no	82.758	85.485	PhosphoSitePlus;EPSD	COSMIC	72.838	Up-regulation
CMGC_GSK_GSK3A_ST	P35222	CTNNB1	P49840	GSK3A	S37	P44L	44	Missense	distal	7	no	82.758	81.795	PhosphoSitePlus;EPSD	COSMIC	72.838	Down-regulation
CMGC_GSK_GSK3A_ST	P35222	CTNNB1	P49840	GSK3A	S37	G34L	34	Missense	distal	-3	no	82.758	82.072	PhosphoSitePlus;EPSD	COSMIC	72.838	Down-regulation
CMGC_GSK_GSK3A_ST	P35222	CTNNB1	P49840	GSK3A	S37	T42I	42	Missense	distal	5	no	82.758	71.326	PhosphoSitePlus;EPSD	COSMIC	72.838	Loss
CMGC_GSK_GSK3A_ST	P35222	CTNNB1	P49840	GSK3A	S37	S33L	33	Missense	distal	-4	no	82.758	76.484	PhosphoSitePlus;EPSD	COSMIC;CCLE	72.838	Down-regulation
CMGC_GSK_GSK3A_ST	P35222	CTNNB1	P49840	GSK3A	S37	T42S	42	Missense	distal	5	no	82.758	82.081	PhosphoSitePlus;EPSD	COSMIC	72.838	Down-regulation
CMGC_GSK_GSK3A_ST	P35222	CTNNB1	P49840	GSK3A	S37	T42K	42	Missense	distal	5	no	82.758	78.150	PhosphoSitePlus;EPSD	COSMIC	72.838	Down-regulation
CMGC_GSK_GSK3A_ST	P35222	CTNNB1	P49840	GSK3A	S37	L31P	31	Missense	distal	-6	no	82.758	82.632	PhosphoSitePlus;EPSD	COSMIC	72.838	Down-regulation
CMGC_GSK_GSK3A_ST	P35222	CTNNB1	P49840	GSK3A	S37	S37L	37	Missense	central	0	yes	82.758	0.000	PhosphoSitePlus;EPSD	COSMIC	72.838	Loss
CMGC_GSK_GSK3A_ST	P35222	CTNNB1	P49840	GSK3A	S37	A39T	39	Missense	proximal	2	no	82.758	84.433	PhosphoSitePlus;EPSD	COSMIC	72.838	Up-regulation
CMGC_GSK_GSK3A_ST	P35222	CTNNB1	P49840	GSK3A	S37	S33N	33	Missense	distal	-4	no	82.758	80.185	PhosphoSitePlus;EPSD	COSMIC	72.838	Down-regulation
CMGC_GSK_GSK3A_ST	P35222	CTNNB1	P49840	GSK3A	S37	H36Y	36	Missense	proximal	-1	no	82.758	83.928	PhosphoSitePlus;EPSD	COSMIC	72.838	Up-regulation
CMGC_GSK_GSK3A_ST	P35222	CTNNB1	P49840	GSK3A	S37	A43P	43	Missense	distal	6	no	82.758	85.303	PhosphoSitePlus;EPSD	COSMIC	72.838	Up-regulation
CMGC_GSK_GSK3A_ST	P35222	CTNNB1	P49840	GSK3A	S37	Y30C	30	Missense	distal	-7	no	82.758	80.435	PhosphoSitePlus;EPSD	COSMIC	72.838	Down-regulation
CMGC_GSK_GSK3A_ST	P35222	CTNNB1	P49840	GSK3A	S37	G38P	38	Missense	proximal	1	no	82.758	93.234	PhosphoSitePlus;EPSD	COSMIC	72.838	Up-regulation
CMGC_GSK_GSK3A_ST	P35222	CTNNB1	P49840	GSK3A	S37	G38D	38	Missense	proximal	1	no	82.758	72.589	PhosphoSitePlus;EPSD	COSMIC	72.838	Loss
CMGC_GSK_GSK3A_ST	P35222	CTNNB1	P49840	GSK3A	S37	T42A	42	Missense	distal	5	no	82.758	81.162	PhosphoSitePlus;EPSD	COSMIC	72.838	Down-regulation
CMGC_GSK_GSK3A_ST	P35222	CTNNB1	P49840	GSK3A	S37	I35M	35	Missense	proximal	-2	no	82.758	82.761	PhosphoSitePlus;EPSD	COSMIC	72.838	Up-regulation
CMGC_GSK_GSK3A_ST	P35222	CTNNB1	P49840	GSK3A	S37	T40S	40	Missense	distal	3	no	82.758	80.735	PhosphoSitePlus;EPSD	COSMIC	72.838	Down-regulation
CMGC_GSK_GSK3A_ST	P35222	CTNNB1	P49840	GSK3A	S37	G34A	34	Missense	distal	-3	no	82.758	83.502	PhosphoSitePlus;EPSD	COSMIC	72.838	Up-regulation
CMGC_GSK_GSK3A_ST	P35222	CTNNB1	P49840	GSK3A	S37	L31W	31	Missense	distal	-6	no	82.758	83.100	PhosphoSitePlus;EPSD	COSMIC	72.838	Up-regulation
CMGC_GSK_GSK3A_ST	P35222	CTNNB1	P49840	GSK3A	S37	T41S	41	Missense	distal	4	no	82.758	83.258	PhosphoSitePlus;EPSD	COSMIC	72.838	Up-regulation
CMGC_GSK_GSK3A_ST	P35222	CTNNB1	P49840	GSK3A	S37	G34I	34	Missense	distal	-3	no	82.758	80.959	PhosphoSitePlus;EPSD	COSMIC	72.838	Down-regulation
CMGC_GSK_GSK3A_ST	P35222	CTNNB1	P49840	GSK3A	S37	I35N	35	Missense	proximal	-2	no	82.758	82.756	PhosphoSitePlus;EPSD	COSMIC	72.838	Down-regulation
CMGC_GSK_GSK3A_ST	P35222	CTNNB1	P49840	GSK3A	S37	T42Q	42	Missense	distal	5	no	82.758	77.239	PhosphoSitePlus;EPSD	COSMIC	72.838	Down-regulation
CMGC_GSK_GSK3A_ST	P35222	CTNNB1	P49840	GSK3A	S37	D32C	32	Missense	distal	-5	no	82.758	83.508	PhosphoSitePlus;EPSD	COSMIC	72.838	Up-regulation
CMGC_GSK_GSK3A_ST	P35222	CTNNB1	P49840	GSK3A	S37	Y30S	30	Missense	distal	-7	no	82.758	82.014	PhosphoSitePlus;EPSD	COSMIC	72.838	Down-regulation
CMGC_GSK_GSK3A_ST	P35222	CTNNB1	P49840	GSK3A	S37	L31M	31	Missense	distal	-6	no	82.758	83.372	PhosphoSitePlus;EPSD	COSMIC	72.838	Up-regulation
CMGC_GSK_GSK3A_ST	P35222	CTNNB1	P49840	GSK3A	S37	A39V	39	Missense	proximal	2	no	82.758	81.941	PhosphoSitePlus;EPSD	COSMIC	72.838	Down-regulation
CMGC_GSK_GSK3A_ST	P35222	CTNNB1	P49840	GSK3A	S37	L31Q	31	Missense	distal	-6	no	82.758	82.624	PhosphoSitePlus;EPSD	COSMIC	72.838	Down-regulation
CMGC_GSK_GSK3A_ST	P35222	CTNNB1	P49840	GSK3A	S37	G34D	34	Missense	distal	-3	no	82.758	82.548	PhosphoSitePlus;EPSD	COSMIC	72.838	Down-regulation
CMGC_GSK_GSK3A_ST	P35222	CTNNB1	P49840	GSK3A	S37	I35K	35	Missense	proximal	-2	no	82.758	84.519	PhosphoSitePlus;EPSD	COSMIC	72.838	Up-regulation
CMGC_GSK_GSK3A_ST	P35222	CTNNB1	P49840	GSK3A	S37	D32F	32	Missense	distal	-5	no	82.758	80.498	PhosphoSitePlus;EPSD	COSMIC	72.838	Down-regulation
CMGC_GSK_GSK3A_ST	P35222	CTNNB1	P49840	GSK3A	S37	G38X	38	Missense	proximal	1	no	82.758	66.086	PhosphoSitePlus;EPSD	COSMIC	72.838	Loss
CMGC_GSK_GSK3A_ST	P35222	CTNNB1	P49840	GSK3A	S37	D32X	32	Missense	distal	-5	no	82.758	84.286	PhosphoSitePlus;EPSD	COSMIC	72.838	Up-regulation
CMGC_GSK_GSK3A_ST	P35222	CTNNB1	P49840	GSK3A	S37	S33K	33	Missense	distal	-4	no	82.758	79.294	PhosphoSitePlus;EPSD	COSMIC	72.838	Down-regulation
CMGC_GSK_GSK3A_ST	P35222	CTNNB1	P49840	GSK3A	S37	I35V	35	Missense	proximal	-2	no	82.758	82.590	PhosphoSitePlus;EPSD	COSMIC	72.838	Down-regulation
CMGC_GSK_GSK3A_ST	P35222	CTNNB1	P49840	GSK3A	S37	G34C	34	Missense	distal	-3	no	82.758	82.290	PhosphoSitePlus;EPSD	COSMIC	72.838	Down-regulation
CMGC_GSK_GSK3A_ST	P35222	CTNNB1	P49840	GSK3A	S37	G38S	38	Missense	proximal	1	no	82.758	77.542	PhosphoSitePlus;EPSD	COSMIC	72.838	Down-regulation
CMGC_GSK_GSK3A_ST	P35222	CTNNB1	P49840	GSK3A	S37	S37V	37	Missense	central	0	yes	82.758	0.000	PhosphoSitePlus;EPSD	COSMIC	72.838	Loss
CMGC_GSK_GSK3A_ST	P35222	CTNNB1	P49840	GSK3A	S37	P44I	44	Missense	distal	7	no	82.758	82.311	PhosphoSitePlus;EPSD	COSMIC	72.838	Down-regulation
CMGC_GSK_GSK3A_ST	P35222	CTNNB1	P49840	GSK3A	S37	I35F	35	Missense	proximal	-2	no	82.758	82.424	PhosphoSitePlus;EPSD	COSMIC	72.838	Down-regulation
CMGC_GSK_GSK3A_ST	P35222	CTNNB1	P49840	GSK3A	S37	T40P	40	Missense	distal	3	no	82.758	82.068	PhosphoSitePlus;EPSD	COSMIC	72.838	Down-regulation
CMGC_GSK_GSK3A_ST	P35222	CTNNB1	P49840	GSK3A	T40	T41P	41	Missense	proximal	1	no	66.376	81.027	EPSD	COSMIC	72.838	Gain
CMGC_GSK_GSK3A_ST	P35222	CTNNB1	P49840	GSK3A	T41	S45T	45	Missense	distal	4	no	88.151	87.650	EPSD;PhosphoSitePlus	COSMIC	72.838	Down-regulation
CMGC_GSK_GSK3A_ST	P35222	CTNNB1	P49840	GSK3A	T41	P44S	44	Missense	distal	3	no	88.151	86.818	EPSD;PhosphoSitePlus	COSMIC	72.838	Down-regulation
CMGC_GSK_GSK3A_ST	P35222	CTNNB1	P49840	GSK3A	T41	A43V	43	Missense	proximal	2	no	88.151	87.333	EPSD;PhosphoSitePlus	COSMIC	72.838	Down-regulation
CMGC_GSK_GSK3A_ST	P35222	CTNNB1	P49840	GSK3A	T41	G48D	48	Missense	distal	7	no	88.151	86.714	EPSD;PhosphoSitePlus	COSMIC	72.838	Down-regulation
CMGC_GSK_GSK3A_ST	P35222	CTNNB1	P49840	GSK3A	T41	A39G	39	Missense	proximal	-2	no	88.151	87.713	EPSD;PhosphoSitePlus	COSMIC	72.838	Down-regulation
CMGC_GSK_GSK3A_ST	P35222	CTNNB1	P49840	GSK3A	T41	G38A	38	Missense	distal	-3	no	88.151	88.895	EPSD;PhosphoSitePlus	COSMIC	72.838	Up-regulation
CMGC_GSK_GSK3A_ST	P35222	CTNNB1	P49840	GSK3A	T41	T40I	40	Missense	proximal	-1	no	88.151	85.253	EPSD;PhosphoSitePlus	COSMIC	72.838	Down-regulation
CMGC_GSK_GSK3A_ST	P35222	CTNNB1	P49840	GSK3A	T41	P44A	44	Missense	distal	3	no	88.151	87.461	EPSD;PhosphoSitePlus	COSMIC	72.838	Down-regulation
CMGC_GSK_GSK3A_ST	P35222	CTNNB1	P49840	GSK3A	T41	I35T	35	Missense	distal	-6	no	88.151	87.691	EPSD;PhosphoSitePlus	COSMIC	72.838	Down-regulation
CMGC_GSK_GSK3A_ST	P35222	CTNNB1	P49840	GSK3A	T41	T41P	41	Missense	central	0	yes	88.151	0.000	EPSD;PhosphoSitePlus	COSMIC	72.838	Loss
CMGC_GSK_GSK3A_ST	P35222	CTNNB1	P49840	GSK3A	T41	T42R	42	Missense	proximal	1	no	88.151	94.149	EPSD;PhosphoSitePlus	COSMIC	72.838	Up-regulation
CMGC_GSK_GSK3A_ST	P35222	CTNNB1	P49840	GSK3A	T41	S45A	45	Missense	distal	4	no	88.151	85.065	EPSD;PhosphoSitePlus	COSMIC	72.838	Down-regulation
CMGC_GSK_GSK3A_ST	P35222	CTNNB1	P49840	GSK3A	T41	H36R	36	Missense	distal	-5	no	88.151	87.950	EPSD;PhosphoSitePlus	COSMIC	72.838	Down-regulation
CMGC_GSK_GSK3A_ST	P35222	CTNNB1	P49840	GSK3A	T41	G48S	48	Missense	distal	7	no	88.151	88.065	EPSD;PhosphoSitePlus	COSMIC	72.838	Down-regulation
CMGC_GSK_GSK3A_ST	P35222	CTNNB1	P49840	GSK3A	T41	T40A	40	Missense	proximal	-1	no	88.151	87.242	EPSD;PhosphoSitePlus	COSMIC	72.838	Down-regulation
CMGC_GSK_GSK3A_ST	P35222	CTNNB1	P49840	GSK3A	T41	A43T	43	Missense	proximal	2	no	88.151	89.826	EPSD;PhosphoSitePlus	COSMIC	72.838	Up-regulation
CMGC_GSK_GSK3A_ST	P35222	CTNNB1	P49840	GSK3A	T41	P44L	44	Missense	distal	3	no	88.151	84.291	EPSD;PhosphoSitePlus	COSMIC	72.838	Down-regulation
CMGC_GSK_GSK3A_ST	P35222	CTNNB1	P49840	GSK3A	T41	G34L	34	Missense	distal	-7	no	88.151	86.280	EPSD;PhosphoSitePlus	COSMIC	72.838	Down-regulation
CMGC_GSK_GSK3A_ST	P35222	CTNNB1	P49840	GSK3A	T41	T42I	42	Missense	proximal	1	no	88.151	82.380	EPSD;PhosphoSitePlus	COSMIC	72.838	Down-regulation
CMGC_GSK_GSK3A_ST	P35222	CTNNB1	P49840	GSK3A	T41	T42S	42	Missense	proximal	1	no	88.151	87.110	EPSD;PhosphoSitePlus	COSMIC	72.838	Down-regulation
CMGC_GSK_GSK3A_ST	P35222	CTNNB1	P49840	GSK3A	T41	T42K	42	Missense	proximal	1	no	88.151	90.198	EPSD;PhosphoSitePlus	COSMIC	72.838	Up-regulation
CMGC_GSK_GSK3A_ST	P35222	CTNNB1	P49840	GSK3A	T41	S47G	47	Missense	distal	6	no	88.151	87.197	EPSD;PhosphoSitePlus	COSMIC	72.838	Down-regulation
CMGC_GSK_GSK3A_ST	P35222	CTNNB1	P49840	GSK3A	T41	G48V	48	Missense	distal	7	no	88.151	86.957	EPSD;PhosphoSitePlus	COSMIC	72.838	Down-regulation
CMGC_GSK_GSK3A_ST	P35222	CTNNB1	P49840	GSK3A	T41	S47N	47	Missense	distal	6	no	88.151	89.505	EPSD;PhosphoSitePlus	COSMIC	72.838	Up-regulation
CMGC_GSK_GSK3A_ST	P35222	CTNNB1	P49840	GSK3A	T41	S37L	37	Missense	distal	-4	no	88.151	81.876	EPSD;PhosphoSitePlus	COSMIC	72.838	Down-regulation
CMGC_GSK_GSK3A_ST	P35222	CTNNB1	P49840	GSK3A	T41	A39T	39	Missense	proximal	-2	no	88.151	88.036	EPSD;PhosphoSitePlus	COSMIC	72.838	Down-regulation
CMGC_GSK_GSK3A_ST	P35222	CTNNB1	P49840	GSK3A	T41	H36Y	36	Missense	distal	-5	no	88.151	88.458	EPSD;PhosphoSitePlus	COSMIC	72.838	Up-regulation
CMGC_GSK_GSK3A_ST	P35222	CTNNB1	P49840	GSK3A	T41	A43P	43	Missense	proximal	2	no	88.151	89.103	EPSD;PhosphoSitePlus	COSMIC	72.838	Up-regulation
CMGC_GSK_GSK3A_ST	P35222	CTNNB1	P49840	GSK3A	T41	L46P	46	Missense	distal	5	no	88.151	97.324	EPSD;PhosphoSitePlus	COSMIC	72.838	Up-regulation
CMGC_GSK_GSK3A_ST	P35222	CTNNB1	P49840	GSK3A	T41	G38P	38	Missense	distal	-3	no	88.151	89.209	EPSD;PhosphoSitePlus	COSMIC	72.838	Up-regulation
CMGC_GSK_GSK3A_ST	P35222	CTNNB1	P49840	GSK3A	T41	G38D	38	Missense	distal	-3	no	88.151	87.941	EPSD;PhosphoSitePlus	COSMIC	72.838	Down-regulation
CMGC_GSK_GSK3A_ST	P35222	CTNNB1	P49840	GSK3A	T41	T42A	42	Missense	proximal	1	no	88.151	89.135	EPSD;PhosphoSitePlus	COSMIC	72.838	Up-regulation
CMGC_GSK_GSK3A_ST	P35222	CTNNB1	P49840	GSK3A	T41	L46V	46	Missense	distal	5	no	88.151	89.235	EPSD;PhosphoSitePlus	COSMIC	72.838	Up-regulation
CMGC_GSK_GSK3A_ST	P35222	CTNNB1	P49840	GSK3A	T41	S47L	47	Missense	distal	6	no	88.151	85.820	EPSD;PhosphoSitePlus	COSMIC	72.838	Down-regulation
CMGC_GSK_GSK3A_ST	P35222	CTNNB1	P49840	GSK3A	T41	I35M	35	Missense	distal	-6	no	88.151	88.359	EPSD;PhosphoSitePlus	COSMIC	72.838	Up-regulation
CMGC_GSK_GSK3A_ST	P35222	CTNNB1	P49840	GSK3A	T41	T40S	40	Missense	proximal	-1	no	88.151	86.468	EPSD;PhosphoSitePlus	COSMIC	72.838	Down-regulation
CMGC_GSK_GSK3A_ST	P35222	CTNNB1	P49840	GSK3A	T41	L46M	46	Missense	distal	5	no	88.151	92.357	EPSD;PhosphoSitePlus	COSMIC	72.838	Up-regulation
CMGC_GSK_GSK3A_ST	P35222	CTNNB1	P49840	GSK3A	T41	G34A	34	Missense	distal	-7	no	88.151	88.915	EPSD;PhosphoSitePlus	COSMIC	72.838	Up-regulation
CMGC_GSK_GSK3A_ST	P35222	CTNNB1	P49840	GSK3A	T41	S47T	47	Missense	distal	6	no	88.151	88.882	EPSD;PhosphoSitePlus	COSMIC	72.838	Up-regulation
CMGC_GSK_GSK3A_ST	P35222	CTNNB1	P49840	GSK3A	T41	G34I	34	Missense	distal	-7	no	88.151	87.159	EPSD;PhosphoSitePlus	COSMIC	72.838	Down-regulation
CMGC_GSK_GSK3A_ST	P35222	CTNNB1	P49840	GSK3A	T41	I35N	35	Missense	distal	-6	no	88.151	88.152	EPSD;PhosphoSitePlus	COSMIC	72.838	Up-regulation
CMGC_GSK_GSK3A_ST	P35222	CTNNB1	P49840	GSK3A	T41	T42Q	42	Missense	proximal	1	no	88.151	92.125	EPSD;PhosphoSitePlus	COSMIC	72.838	Up-regulation
CMGC_GSK_GSK3A_ST	P35222	CTNNB1	P49840	GSK3A	T41	S47C	47	Missense	distal	6	no	88.151	85.393	EPSD;PhosphoSitePlus	COSMIC	72.838	Down-regulation
CMGC_GSK_GSK3A_ST	P35222	CTNNB1	P49840	GSK3A	T41	S47R	47	Missense	distal	6	no	88.151	89.556	EPSD;PhosphoSitePlus	COSMIC	72.838	Up-regulation
CMGC_GSK_GSK3A_ST	P35222	CTNNB1	P49840	GSK3A	T41	A39V	39	Missense	proximal	-2	no	88.151	87.401	EPSD;PhosphoSitePlus	COSMIC	72.838	Down-regulation
CMGC_GSK_GSK3A_ST	P35222	CTNNB1	P49840	GSK3A	T41	S45E	45	Missense	distal	4	no	88.151	84.191	EPSD;PhosphoSitePlus	COSMIC	72.838	Down-regulation
CMGC_GSK_GSK3A_ST	P35222	CTNNB1	P49840	GSK3A	T41	G34D	34	Missense	distal	-7	no	88.151	86.540	EPSD;PhosphoSitePlus	COSMIC	72.838	Down-regulation
CMGC_GSK_GSK3A_ST	P35222	CTNNB1	P49840	GSK3A	T41	S37T	37	Missense	distal	-4	no	88.151	88.960	EPSD;PhosphoSitePlus	COSMIC	72.838	Up-regulation
CMGC_GSK_GSK3A_ST	P35222	CTNNB1	P49840	GSK3A	T41	I35K	35	Missense	distal	-6	no	88.151	87.386	EPSD;PhosphoSitePlus	COSMIC	72.838	Down-regulation
CMGC_GSK_GSK3A_ST	P35222	CTNNB1	P49840	GSK3A	T41	S45N	45	Missense	distal	4	no	88.151	81.762	EPSD;PhosphoSitePlus	COSMIC	72.838	Down-regulation
CMGC_GSK_GSK3A_ST	P35222	CTNNB1	P49840	GSK3A	T41	G38X	38	Missense	distal	-3	no	88.151	87.725	EPSD;PhosphoSitePlus	COSMIC	72.838	Down-regulation
CMGC_GSK_GSK3A_ST	P35222	CTNNB1	P49840	GSK3A	T41	L46Q	46	Missense	distal	5	no	88.151	86.925	EPSD;PhosphoSitePlus	COSMIC	72.838	Down-regulation
CMGC_GSK_GSK3A_ST	P35222	CTNNB1	P49840	GSK3A	T41	I35V	35	Missense	distal	-6	no	88.151	88.597	EPSD;PhosphoSitePlus	COSMIC	72.838	Up-regulation
CMGC_GSK_GSK3A_ST	P35222	CTNNB1	P49840	GSK3A	T41	S45X	45	Missense	distal	4	no	88.151	71.546	EPSD;PhosphoSitePlus	COSMIC	72.838	Loss
CMGC_GSK_GSK3A_ST	P35222	CTNNB1	P49840	GSK3A	T41	G34C	34	Missense	distal	-7	no	88.151	86.377	EPSD;PhosphoSitePlus	COSMIC	72.838	Down-regulation
CMGC_GSK_GSK3A_ST	P35222	CTNNB1	P49840	GSK3A	T41	G38S	38	Missense	distal	-3	no	88.151	88.569	EPSD;PhosphoSitePlus	COSMIC	72.838	Up-regulation
CMGC_GSK_GSK3A_ST	P35222	CTNNB1	P49840	GSK3A	T41	S37V	37	Missense	distal	-4	no	88.151	82.373	EPSD;PhosphoSitePlus	COSMIC	72.838	Down-regulation
CMGC_GSK_GSK3A_ST	P35222	CTNNB1	P49840	GSK3A	T41	P44I	44	Missense	distal	3	no	88.151	86.117	EPSD;PhosphoSitePlus	COSMIC	72.838	Down-regulation
CMGC_GSK_GSK3A_ST	P35222	CTNNB1	P49840	GSK3A	T41	I35F	35	Missense	distal	-6	no	88.151	89.195	EPSD;PhosphoSitePlus	COSMIC	72.838	Up-regulation
CMGC_GSK_GSK3A_ST	P35222	CTNNB1	P49840	GSK3A	T41	S47I	47	Missense	distal	6	no	88.151	86.454	EPSD;PhosphoSitePlus	COSMIC	72.838	Down-regulation
CMGC_GSK_GSK3A_ST	P35222	CTNNB1	P49840	GSK3A	T41	S47Y	47	Missense	distal	6	no	88.151	88.821	EPSD;PhosphoSitePlus	COSMIC	72.838	Up-regulation
CMGC_GSK_GSK3A_ST	P35222	CTNNB1	P49840	GSK3A	T41	T40P	40	Missense	proximal	-1	no	88.151	87.365	EPSD;PhosphoSitePlus	COSMIC	72.838	Down-regulation
CMGC_GSK_GSK3A_ST	P35222	CTNNB1	P49840	GSK3A	T42	A43P	43	Missense	proximal	1	no	63.578	77.244	EPSD	COSMIC	72.838	Gain
CMGC_GSK_GSK3A_ST	P35222	CTNNB1	P49840	GSK3A	S45	P44S	44	Missense	proximal	-1	no	90.132	89.234	EPSD	COSMIC	72.838	Down-regulation
CMGC_GSK_GSK3A_ST	P35222	CTNNB1	P49840	GSK3A	S45	A43V	43	Missense	proximal	-2	no	90.132	89.382	EPSD	COSMIC	72.838	Down-regulation
CMGC_GSK_GSK3A_ST	P35222	CTNNB1	P49840	GSK3A	S45	G48D	48	Missense	distal	3	no	90.132	92.609	EPSD	COSMIC	72.838	Up-regulation
CMGC_GSK_GSK3A_ST	P35222	CTNNB1	P49840	GSK3A	S45	A39G	39	Missense	distal	-6	no	90.132	89.652	EPSD	COSMIC	72.838	Down-regulation
CMGC_GSK_GSK3A_ST	P35222	CTNNB1	P49840	GSK3A	S45	N51T	51	Missense	distal	6	no	90.132	89.508	EPSD	COSMIC	72.838	Down-regulation
CMGC_GSK_GSK3A_ST	P35222	CTNNB1	P49840	GSK3A	S45	P52L	52	Missense	distal	7	no	90.132	89.168	EPSD	COSMIC	72.838	Down-regulation
CMGC_GSK_GSK3A_ST	P35222	CTNNB1	P49840	GSK3A	S45	N51S	51	Missense	distal	6	no	90.132	88.777	EPSD	COSMIC	72.838	Down-regulation
CMGC_GSK_GSK3A_ST	P35222	CTNNB1	P49840	GSK3A	S45	G38A	38	Missense	distal	-7	no	90.132	90.896	EPSD	COSMIC	72.838	Up-regulation
CMGC_GSK_GSK3A_ST	P35222	CTNNB1	P49840	GSK3A	S45	T40I	40	Missense	distal	-5	no	90.132	88.537	EPSD	COSMIC	72.838	Down-regulation
CMGC_GSK_GSK3A_ST	P35222	CTNNB1	P49840	GSK3A	S45	P44A	44	Missense	proximal	-1	no	90.132	90.008	EPSD	COSMIC	72.838	Down-regulation
CMGC_GSK_GSK3A_ST	P35222	CTNNB1	P49840	GSK3A	S45	T41P	41	Missense	distal	-4	no	90.132	85.736	EPSD	COSMIC	72.838	Down-regulation
CMGC_GSK_GSK3A_ST	P35222	CTNNB1	P49840	GSK3A	S45	K49R	49	Missense	distal	4	no	90.132	83.352	EPSD	COSMIC	72.838	Down-regulation
CMGC_GSK_GSK3A_ST	P35222	CTNNB1	P49840	GSK3A	S45	T42R	42	Missense	distal	-3	no	90.132	88.726	EPSD	COSMIC	72.838	Down-regulation
CMGC_GSK_GSK3A_ST	P35222	CTNNB1	P49840	GSK3A	S45	S45A	45	Missense	central	0	yes	90.132	0.000	EPSD	COSMIC	72.838	Loss
CMGC_GSK_GSK3A_ST	P35222	CTNNB1	P49840	GSK3A	S45	G48S	48	Missense	distal	3	no	90.132	90.738	EPSD	COSMIC	72.838	Up-regulation
CMGC_GSK_GSK3A_ST	P35222	CTNNB1	P49840	GSK3A	S45	T40A	40	Missense	distal	-5	no	90.132	90.860	EPSD	COSMIC	72.838	Up-regulation
CMGC_GSK_GSK3A_ST	P35222	CTNNB1	P49840	GSK3A	S45	A43T	43	Missense	proximal	-2	no	90.132	90.017	EPSD	COSMIC	72.838	Down-regulation
CMGC_GSK_GSK3A_ST	P35222	CTNNB1	P49840	GSK3A	S45	P44L	44	Missense	proximal	-1	no	90.132	88.977	EPSD	COSMIC	72.838	Down-regulation
CMGC_GSK_GSK3A_ST	P35222	CTNNB1	P49840	GSK3A	S45	T42I	42	Missense	distal	-3	no	90.132	86.762	EPSD	COSMIC	72.838	Down-regulation
CMGC_GSK_GSK3A_ST	P35222	CTNNB1	P49840	GSK3A	S45	T42S	42	Missense	distal	-3	no	90.132	88.979	EPSD	COSMIC	72.838	Down-regulation
CMGC_GSK_GSK3A_ST	P35222	CTNNB1	P49840	GSK3A	S45	T42K	42	Missense	distal	-3	no	90.132	88.327	EPSD	COSMIC	72.838	Down-regulation
CMGC_GSK_GSK3A_ST	P35222	CTNNB1	P49840	GSK3A	S45	S47G	47	Missense	proximal	2	no	90.132	88.700	EPSD	COSMIC	72.838	Down-regulation
CMGC_GSK_GSK3A_ST	P35222	CTNNB1	P49840	GSK3A	S45	G48V	48	Missense	distal	3	no	90.132	90.615	EPSD	COSMIC	72.838	Up-regulation
CMGC_GSK_GSK3A_ST	P35222	CTNNB1	P49840	GSK3A	S45	S47N	47	Missense	proximal	2	no	90.132	87.570	EPSD	COSMIC	72.838	Down-regulation
CMGC_GSK_GSK3A_ST	P35222	CTNNB1	P49840	GSK3A	S45	A39T	39	Missense	distal	-6	no	90.132	89.549	EPSD	COSMIC	72.838	Down-regulation
CMGC_GSK_GSK3A_ST	P35222	CTNNB1	P49840	GSK3A	S45	K49T	49	Missense	distal	4	no	90.132	92.247	EPSD	COSMIC	72.838	Up-regulation
CMGC_GSK_GSK3A_ST	P35222	CTNNB1	P49840	GSK3A	S45	G50D	50	Missense	distal	5	no	90.132	88.853	EPSD	COSMIC	72.838	Down-regulation
CMGC_GSK_GSK3A_ST	P35222	CTNNB1	P49840	GSK3A	S45	A43P	43	Missense	proximal	-2	no	90.132	90.585	EPSD	COSMIC	72.838	Up-regulation
CMGC_GSK_GSK3A_ST	P35222	CTNNB1	P49840	GSK3A	S45	L46P	46	Missense	proximal	1	no	90.132	104.183	EPSD	COSMIC	72.838	Up-regulation
CMGC_GSK_GSK3A_ST	P35222	CTNNB1	P49840	GSK3A	S45	G38P	38	Missense	distal	-7	no	90.132	90.093	EPSD	COSMIC	72.838	Down-regulation
CMGC_GSK_GSK3A_ST	P35222	CTNNB1	P49840	GSK3A	S45	G38D	38	Missense	distal	-7	no	90.132	88.521	EPSD	COSMIC	72.838	Down-regulation
CMGC_GSK_GSK3A_ST	P35222	CTNNB1	P49840	GSK3A	S45	T42A	42	Missense	distal	-3	no	90.132	89.304	EPSD	COSMIC	72.838	Down-regulation
CMGC_GSK_GSK3A_ST	P35222	CTNNB1	P49840	GSK3A	S45	L46V	46	Missense	proximal	1	no	90.132	80.694	EPSD	COSMIC	72.838	Down-regulation
CMGC_GSK_GSK3A_ST	P35222	CTNNB1	P49840	GSK3A	S45	S47L	47	Missense	proximal	2	no	90.132	90.111	EPSD	COSMIC	72.838	Down-regulation
CMGC_GSK_GSK3A_ST	P35222	CTNNB1	P49840	GSK3A	S45	T40S	40	Missense	distal	-5	no	90.132	90.459	EPSD	COSMIC	72.838	Up-regulation
CMGC_GSK_GSK3A_ST	P35222	CTNNB1	P49840	GSK3A	S45	K49L	49	Missense	distal	4	no	90.132	87.338	EPSD	COSMIC	72.838	Down-regulation
CMGC_GSK_GSK3A_ST	P35222	CTNNB1	P49840	GSK3A	S45	L46M	46	Missense	proximal	1	no	90.132	70.706	EPSD	COSMIC	72.838	Loss
CMGC_GSK_GSK3A_ST	P35222	CTNNB1	P49840	GSK3A	S45	S47T	47	Missense	proximal	2	no	90.132	91.543	EPSD	COSMIC	72.838	Up-regulation
CMGC_GSK_GSK3A_ST	P35222	CTNNB1	P49840	GSK3A	S45	T41S	41	Missense	distal	-4	no	90.132	89.323	EPSD	COSMIC	72.838	Down-regulation
CMGC_GSK_GSK3A_ST	P35222	CTNNB1	P49840	GSK3A	S45	T42Q	42	Missense	distal	-3	no	90.132	88.377	EPSD	COSMIC	72.838	Down-regulation
CMGC_GSK_GSK3A_ST	P35222	CTNNB1	P49840	GSK3A	S45	S47C	47	Missense	proximal	2	no	90.132	87.385	EPSD	COSMIC	72.838	Down-regulation
CMGC_GSK_GSK3A_ST	P35222	CTNNB1	P49840	GSK3A	S45	K49E	49	Missense	distal	4	no	90.132	88.788	EPSD	COSMIC	72.838	Down-regulation
CMGC_GSK_GSK3A_ST	P35222	CTNNB1	P49840	GSK3A	S45	S47R	47	Missense	proximal	2	no	90.132	90.335	EPSD	COSMIC	72.838	Up-regulation
CMGC_GSK_GSK3A_ST	P35222	CTNNB1	P49840	GSK3A	S45	A39V	39	Missense	distal	-6	no	90.132	90.455	EPSD	COSMIC	72.838	Up-regulation
CMGC_GSK_GSK3A_ST	P35222	CTNNB1	P49840	GSK3A	S45	S45E	45	Missense	central	0	yes	90.132	0.000	EPSD	COSMIC	72.838	Loss
CMGC_GSK_GSK3A_ST	P35222	CTNNB1	P49840	GSK3A	S45	G50S	50	Missense	distal	5	no	90.132	90.165	EPSD	COSMIC	72.838	Up-regulation
CMGC_GSK_GSK3A_ST	P35222	CTNNB1	P49840	GSK3A	S45	S45N	45	Missense	central	0	yes	90.132	0.000	EPSD	COSMIC	72.838	Loss
CMGC_GSK_GSK3A_ST	P35222	CTNNB1	P49840	GSK3A	S45	G38X	38	Missense	distal	-7	no	90.132	88.949	EPSD	COSMIC	72.838	Down-regulation
CMGC_GSK_GSK3A_ST	P35222	CTNNB1	P49840	GSK3A	S45	L46Q	46	Missense	proximal	1	no	90.132	93.507	EPSD	COSMIC	72.838	Up-regulation
CMGC_GSK_GSK3A_ST	P35222	CTNNB1	P49840	GSK3A	S45	S45X	45	Missense	central	0	yes	90.132	0.000	EPSD	COSMIC	72.838	Loss
CMGC_GSK_GSK3A_ST	P35222	CTNNB1	P49840	GSK3A	S45	G38S	38	Missense	distal	-7	no	90.132	89.937	EPSD	COSMIC	72.838	Down-regulation
CMGC_GSK_GSK3A_ST	P35222	CTNNB1	P49840	GSK3A	S45	P44I	44	Missense	proximal	-1	no	90.132	88.019	EPSD	COSMIC	72.838	Down-regulation
CMGC_GSK_GSK3A_ST	P35222	CTNNB1	P49840	GSK3A	S45	S47I	47	Missense	proximal	2	no	90.132	87.763	EPSD	COSMIC	72.838	Down-regulation
CMGC_GSK_GSK3A_ST	P35222	CTNNB1	P49840	GSK3A	S45	S47Y	47	Missense	proximal	2	no	90.132	90.012	EPSD	COSMIC	72.838	Down-regulation
CMGC_GSK_GSK3A_ST	P35222	CTNNB1	P49840	GSK3A	S45	T40P	40	Missense	distal	-5	no	90.132	90.373	EPSD	COSMIC	72.838	Up-regulation
CMGC_GSK_GSK3A_ST	P35222	CTNNB1	P49840	GSK3A	S47	N51T	51	Missense	distal	4	no	72.524	78.413	EPSD	COSMIC	72.838	Gain
CMGC_GSK_GSK3A_ST	P35222	CTNNB1	P49840	GSK3A	S47	E53K	53	Missense	distal	6	no	72.524	73.070	EPSD	COSMIC	72.838	Gain
CMGC_GSK_GSK3A_ST	P35222	CTNNB1	P49840	GSK3A	S47	N51S	51	Missense	distal	4	no	72.524	78.913	EPSD	COSMIC	72.838	Gain
CMGC_GSK_GSK3A_ST	P35222	CTNNB1	P49840	GSK3A	S47	A43T	43	Missense	distal	-4	no	72.524	78.280	EPSD	COSMIC	72.838	Gain
CMGC_GSK_GSK3A_ST	P35222	CTNNB1	P49840	GSK3A	S47	T42S	42	Missense	distal	-5	no	72.524	72.852	EPSD	COSMIC	72.838	Gain
CMGC_GSK_GSK3A_ST	P35222	CTNNB1	P49840	GSK3A	S47	G50D	50	Missense	distal	3	no	72.524	75.002	EPSD	COSMIC	72.838	Gain
CMGC_GSK_GSK3A_ST	P35222	CTNNB1	P49840	GSK3A	S47	A43P	43	Missense	distal	-4	no	72.524	73.885	EPSD	COSMIC	72.838	Gain
CMGC_GSK_GSK3A_ST	P35222	CTNNB1	P49840	GSK3A	S47	L46P	46	Missense	proximal	-1	no	72.524	73.679	EPSD	COSMIC	72.838	Gain
CMGC_GSK_GSK3A_ST	P35222	CTNNB1	P49840	GSK3A	S47	T42A	42	Missense	distal	-5	no	72.524	73.253	EPSD	COSMIC	72.838	Gain
CMGC_GSK_GSK3A_ST	P35222	CTNNB1	P49840	GSK3A	S47	L46V	46	Missense	proximal	-1	no	72.524	73.015	EPSD	COSMIC	72.838	Gain
CMGC_GSK_GSK3A_ST	P35222	CTNNB1	P49840	GSK3A	S47	L46M	46	Missense	proximal	-1	no	72.524	72.846	EPSD	COSMIC	72.838	Gain
CMGC_GSK_GSK3A_ST	P35222	CTNNB1	P49840	GSK3A	S47	T42Q	42	Missense	distal	-5	no	72.524	73.527	EPSD	COSMIC	72.838	Gain
CMGC_GSK_GSK3A_ST	P35222	CTNNB1	P49840	GSK3A	S47	G50S	50	Missense	distal	3	no	72.524	73.131	EPSD	COSMIC	72.838	Gain
CMGC_GSK_GSK3A_ST	P35222	CTNNB1	P49840	GSK3A	S47	L46Q	46	Missense	proximal	-1	no	72.524	73.657	EPSD	COSMIC	72.838	Gain
CMGC_GSK_GSK3A_ST	P35222	CTNNB1	P49840	GSK3A	T112	Q108H	108	Missense	distal	-4	no	71.986	78.003	EPSD	COSMIC	72.838	Gain
CMGC_GSK_GSK3A_ST	P35222	CTNNB1	P49840	GSK3A	T112	S111P	111	Missense	proximal	-1	no	71.986	72.883	EPSD	COSMIC	72.838	Gain
CMGC_GSK_GSK3A_ST	P35222	CTNNB1	P49840	GSK3A	S179	H176R	176	Missense	distal	-3	no	75.198	74.469	EPSD	COSMIC	72.838	Down-regulation
CMGC_GSK_GSK3A_ST	P35222	CTNNB1	P49840	GSK3A	S179	A183S	183	Missense	distal	4	no	75.198	78.284	EPSD	COSMIC	72.838	Up-regulation
CMGC_GSK_GSK3A_ST	P35222	CTNNB1	P49840	GSK3A	S179	Q177P	177	Missense	proximal	-2	no	75.198	75.322	EPSD	COSMIC	72.838	Up-regulation
CMGC_GSK_GSK3A_ST	P35222	CTNNB1	P49840	GSK3A	S179	V175I	175	Missense	distal	-4	no	75.198	75.191	EPSD	COSMIC	72.838	Down-regulation
CMGC_GSK_GSK3A_ST	P35222	CTNNB1	P49840	GSK3A	S179	A183T	183	Missense	distal	4	no	75.198	77.783	EPSD	COSMIC	72.838	Up-regulation
CMGC_GSK_GSK3A_ST	P35222	CTNNB1	P49840	GSK3A	S179	E182D	182	Missense	distal	3	no	75.198	75.345	EPSD	COSMIC	72.838	Up-regulation
CMGC_GSK_GSK3A_ST	P35222	CTNNB1	P49840	GSK3A	S179	R185K	185	Missense	distal	6	no	75.198	74.879	EPSD	COSMIC	72.838	Down-regulation
CMGC_GSK_GSK3A_ST	P35222	CTNNB1	P49840	GSK3A	S196	P192S	192	Missense	distal	-4	no	70.144	73.731	EPSD	COSMIC	72.838	Gain
CMGC_GSK_GSK3A_ST	P35222	CTNNB1	P49840	GSK3A	S196	P192H	192	Missense	distal	-4	no	70.144	73.327	EPSD	COSMIC	72.838	Gain
CMGC_GSK_GSK3A_ST	P35222	CTNNB1	P49840	GSK3A	S246	M243T	243	Missense	distal	-3	no	78.466	79.535	EPSD	COSMIC	72.838	Up-regulation
CMGC_GSK_GSK3A_ST	P35222	CTNNB1	P49840	GSK3A	S246	S246L	246	Missense	central	0	yes	78.466	0.000	EPSD	COSMIC	72.838	Loss
CMGC_GSK_GSK3A_ST	P35222	CTNNB1	P49840	GSK3A	S246	G245A	245	Missense	proximal	-1	no	78.466	79.264	EPSD	COSMIC;GDSC	72.838	Up-regulation
CMGC_GSK_GSK3A_ST	P35222	CTNNB1	P49840	GSK3A	S246	G245D	245	Missense	proximal	-1	no	78.466	77.849	EPSD	COSMIC	72.838	Down-regulation
CMGC_GSK_GSK3A_ST	P35222	CTNNB1	P49840	GSK3A	S246	A239V	239	Missense	distal	-7	no	78.466	77.592	EPSD	COSMIC	72.838	Down-regulation
CMGC_GSK_GSK3A_ST	P35222	CTNNB1	P49840	GSK3A	S246	K242E	242	Missense	distal	-4	no	78.466	80.260	EPSD	COSMIC	72.838	Up-regulation
CMGC_GSK_GSK3A_ST	P35222	CTNNB1	P49840	GSK3A	S246	A239G	239	Missense	distal	-7	no	78.466	77.701	EPSD	COSMIC	72.838	Down-regulation
CMGC_GSK_GSK3A_ST	P35222	CTNNB1	P49840	GSK3A	T332	L337P	337	Missense	distal	5	no	67.776	76.950	EPSD	COSMIC	72.838	Gain
CMGC_GSK_GSK3A_ST	P35222	CTNNB1	P49840	GSK3A	T393	G397V	397	Missense	distal	4	no	67.632	79.591	EPSD	COSMIC	72.838	Gain
CMGC_GSK_GSK3A_ST	P35222	CTNNB1	P49840	GSK3A	T547	T551K	551	Missense	distal	4	no	77.744	75.629	EPSD	COSMIC	72.838	Down-regulation
CMGC_GSK_GSK3A_ST	P35222	CTNNB1	P49840	GSK3A	T547	R549C	549	Missense	proximal	2	no	77.744	74.794	EPSD	COSMIC	72.838	Down-regulation
CMGC_GSK_GSK3A_ST	P35222	CTNNB1	P49840	GSK3A	T547	Q545K	545	Missense	proximal	-2	no	77.744	78.593	EPSD	COSMIC	72.838	Up-regulation
CMGC_GSK_GSK3A_ST	P35222	CTNNB1	P49840	GSK3A	T547	A543T	543	Missense	distal	-4	no	77.744	83.500	EPSD	COSMIC	72.838	Up-regulation
CMGC_GSK_GSK3A_ST	P35222	CTNNB1	P49840	GSK3A	T547	R550H	550	Missense	distal	3	no	77.744	81.755	EPSD	COSMIC	72.838	Up-regulation
CMGC_GSK_GSK3A_ST	P35222	CTNNB1	P49840	GSK3A	T547	L540F	540	Missense	distal	-7	no	77.744	76.342	EPSD	COSMIC	72.838	Down-regulation
CMGC_GSK_GSK3A_ST	P35222	CTNNB1	P49840	GSK3A	T547	R550L	550	Missense	distal	3	no	77.744	74.931	EPSD	COSMIC	72.838	Down-regulation
CMGC_GSK_GSK3A_ST	P35222	CTNNB1	P49840	GSK3A	T547	A543V	543	Missense	distal	-4	no	77.744	76.913	EPSD	COSMIC	72.838	Down-regulation
CMGC_GSK_GSK3A_ST	P35222	CTNNB1	P49840	GSK3A	T547	D546E	546	Missense	proximal	-1	no	77.744	79.433	EPSD	COSMIC	72.838	Up-regulation
CMGC_GSK_GSK3A_ST	P35222	CTNNB1	P49840	GSK3A	T547	S552F	552	Missense	distal	5	no	77.744	80.254	EPSD	COSMIC	72.838	Up-regulation
CMGC_GSK_GSK3A_ST	P35222	CTNNB1	P49840	GSK3A	T547	G554D	554	Missense	distal	7	no	77.744	76.307	EPSD	COSMIC	72.838	Down-regulation
CMGC_GSK_GSK3A_ST	P35222	CTNNB1	P49840	GSK3A	T547	R550Q	550	Missense	distal	3	no	77.744	75.910	EPSD	COSMIC	72.838	Down-regulation
CMGC_GSK_GSK3A_ST	P35222	CTNNB1	P49840	GSK3A	T547	T551I	551	Missense	distal	4	no	77.744	74.171	EPSD	COSMIC	72.838	Down-regulation
CMGC_GSK_GSK3A_ST	P35222	CTNNB1	P49840	GSK3A	T653	T653R	653	Missense	central	0	yes	74.760	0.000	EPSD	COSMIC	72.838	Loss
CMGC_GSK_GSK3A_ST	P35222	CTNNB1	P49840	GSK3A	T653	A657T	657	Missense	distal	4	no	74.760	77.346	EPSD	COSMIC	72.838	Up-regulation
CMGC_GSK_GSK3A_ST	P35222	CTNNB1	P49840	GSK3A	T653	R647G	647	Missense	distal	-6	no	74.760	74.603	EPSD	COSMIC	72.838	Down-regulation
CMGC_GSK_GSK3A_ST	P35222	CTNNB1	P49840	GSK3A	T653	A652V	652	Missense	proximal	-1	no	74.760	74.219	EPSD	COSMIC	72.838	Down-regulation
CMGC_GSK_GSK3A_ST	P35222	CTNNB1	P49840	GSK3A	T653	S646F	646	Missense	distal	-7	no	74.760	71.682	EPSD	COSMIC	72.838	Loss
CMGC_GSK_GSK3A_ST	P35222	CTNNB1	P49840	GSK3A	T653	V658F	658	Missense	distal	5	no	74.760	79.802	EPSD	COSMIC;GDSC	72.838	Up-regulation
CMGC_GSK_GSK3A_ST	P35222	CTNNB1	P49840	GSK3A	T653	L659S	659	Missense	distal	6	no	74.760	77.091	EPSD	COSMIC	72.838	Up-regulation
CMGC_GSK_GSK3A_ST	P35222	CTNNB1	P49840	GSK3A	T653	V651F	651	Missense	proximal	-2	no	74.760	74.594	EPSD	COSMIC	72.838	Down-regulation
CMGC_GSK_GSK3A_ST	P35222	CTNNB1	P49840	GSK3A	T653	A656T	656	Missense	distal	3	no	74.760	76.141	EPSD	COSMIC	72.838	Up-regulation
CMGC_GSK_GSK3A_ST	Q9Y6Q9	NCOA3	P49840	GSK3A	S284	M289L	289	Missense	distal	5	no	78.673	74.467	EPSD	COSMIC	72.838	Down-regulation
CMGC_GSK_GSK3A_ST	Q9Y6Q9	NCOA3	P49840	GSK3A	S284	S288F	288	Missense	distal	4	no	78.673	56.382	EPSD	COSMIC	72.838	Loss
CMGC_GSK_GSK3A_ST	Q9Y6Q9	NCOA3	P49840	GSK3A	S284	R286K	286	Missense	proximal	2	no	78.673	79.995	EPSD	COSMIC	72.838	Up-regulation
CMGC_GSK_GSK3A_ST	Q9Y6Q9	NCOA3	P49840	GSK3A	S284	V277A	277	Missense	distal	-7	no	78.673	79.548	EPSD	COSMIC	72.838	Up-regulation
CMGC_GSK_GSK3A_ST	Q9Y6Q9	NCOA3	P49840	GSK3A	S284	T282P	282	Missense	proximal	-2	no	78.673	79.242	EPSD	COSMIC	72.838	Up-regulation
CMGC_GSK_GSK3A_ST	Q9Y6Q9	NCOA3	P49840	GSK3A	S413	S414N	414	Missense	proximal	1	no	73.868	23.425	EPSD	COSMIC	72.838	Loss
CMGC_GSK_GSK3A_ST	Q9Y6Q9	NCOA3	P49840	GSK3A	S413	S414L	414	Missense	proximal	1	no	73.868	75.508	EPSD	COSMIC	72.838	Up-regulation
CMGC_GSK_GSK3A_ST	Q9Y6Q9	NCOA3	P49840	GSK3A	T425	Q427H	427	Missense	proximal	2	no	81.714	81.475	EPSD	COSMIC	72.838	Down-regulation
CMGC_GSK_GSK3A_ST	Q9Y6Q9	NCOA3	P49840	GSK3A	T425	P422A	422	Missense	distal	-3	no	81.714	81.400	EPSD	COSMIC	72.838	Down-regulation
CMGC_GSK_GSK3A_ST	Q9Y6Q9	NCOA3	P49840	GSK3A	S429	Q427H	427	Missense	proximal	-2	no	77.632	77.503	EPSD	COSMIC	72.838	Down-regulation
CMGC_GSK_GSK3A_ST	Q9Y6Q9	NCOA3	P49840	GSK3A	S429	P422A	422	Missense	distal	-7	no	77.632	78.435	EPSD	COSMIC	72.838	Up-regulation
CMGC_GSK_GSK3A_ST	Q9Y6Q9	NCOA3	P49840	GSK3A	S450	S452P	452	Missense	proximal	2	no	78.726	79.415	EPSD	COSMIC;GDSC;CCLE	72.838	Up-regulation
CMGC_GSK_GSK3A_ST	Q9Y6Q9	NCOA3	P49840	GSK3A	S465	N462S	462	Missense	distal	-3	no	78.023	78.865	EPSD	COSMIC	72.838	Up-regulation
CMGC_GSK_GSK3A_ST	Q9Y6Q9	NCOA3	P49840	GSK3A	S465	G460E	460	Missense	distal	-5	no	78.023	77.413	EPSD	COSMIC	72.838	Down-regulation
CMGC_GSK_GSK3A_ST	Q9Y6Q9	NCOA3	P49840	GSK3A	S465	G469W	469	Missense	distal	4	no	78.023	75.394	EPSD	COSMIC	72.838	Down-regulation
CMGC_GSK_GSK3A_ST	Q9Y6Q9	NCOA3	P49840	GSK3A	S465	P471H	471	Missense	distal	6	no	78.023	80.359	EPSD	COSMIC	72.838	Up-regulation
CMGC_GSK_GSK3A_ST	Q9Y6Q9	NCOA3	P49840	GSK3A	S470	G469W	469	Missense	proximal	-1	no	88.413	88.201	EPSD	COSMIC	72.838	Down-regulation
CMGC_GSK_GSK3A_ST	Q9Y6Q9	NCOA3	P49840	GSK3A	S470	P471H	471	Missense	proximal	1	no	88.413	61.999	EPSD	COSMIC	72.838	Loss
CMGC_GSK_GSK3A_ST	Q9Y6Q9	NCOA3	P49840	GSK3A	S505	P499L	499	Missense	distal	-6	no	80.489	80.615	EPSD;PhosphoSitePlus	COSMIC;GDSC;CCLE	72.838	Up-regulation
CMGC_GSK_GSK3A_ST	Q9Y6Q9	NCOA3	P49840	GSK3A	S505	V503M	503	Missense	proximal	-2	no	80.489	80.659	EPSD;PhosphoSitePlus	COSMIC	72.838	Up-regulation
CMGC_GSK_GSK3A_ST	Q9Y6Q9	NCOA3	P49840	GSK3A	S505	H504Y	504	Missense	proximal	-1	no	80.489	81.659	EPSD;PhosphoSitePlus	COSMIC	72.838	Up-regulation
CMGC_GSK_GSK3A_ST	Q9Y6Q9	NCOA3	P49840	GSK3A	S505	A508T	508	Missense	distal	3	no	80.489	81.869	EPSD;PhosphoSitePlus	COSMIC;GDSC;CCLE	72.838	Up-regulation
CMGC_GSK_GSK3A_ST	Q9Y6Q9	NCOA3	P49840	GSK3A	S509	V503M	503	Missense	distal	-6	no	82.392	82.153	PhosphoSitePlus;EPSD	COSMIC	72.838	Down-regulation
CMGC_GSK_GSK3A_ST	Q9Y6Q9	NCOA3	P49840	GSK3A	S509	H504Y	504	Missense	distal	-5	no	82.392	82.699	PhosphoSitePlus;EPSD	COSMIC	72.838	Up-regulation
CMGC_GSK_GSK3A_ST	Q9Y6Q9	NCOA3	P49840	GSK3A	S509	A508T	508	Missense	proximal	-1	no	82.392	83.301	PhosphoSitePlus;EPSD	COSMIC;GDSC;CCLE	72.838	Up-regulation
CMGC_GSK_GSK3A_ST	Q9Y6Q9	NCOA3	P49840	GSK3A	S543	K547T	547	Missense	distal	4	no	82.446	84.561	EPSD	COSMIC	72.838	Up-regulation
CMGC_GSK_GSK3A_ST	Q9Y6Q9	NCOA3	P49840	GSK3A	S543	S543P	543	Missense	central	0	yes	82.446	0.000	EPSD	COSMIC	72.838	Loss
CMGC_GSK_GSK3A_ST	Q9Y6Q9	NCOA3	P49840	GSK3A	S543	D549N	549	Missense	distal	6	no	82.446	84.038	EPSD	COSMIC	72.838	Up-regulation
CMGC_GSK_GSK3A_ST	Q9Y6Q9	NCOA3	P49840	GSK3A	S551	K547T	547	Missense	distal	-4	no	70.666	74.939	EPSD	COSMIC	72.838	Gain
CMGC_GSK_GSK3A_ST	Q9Y6Q9	NCOA3	P49840	GSK3A	S567	D566Y	566	Missense	proximal	-1	no	71.148	73.110	EPSD	COSMIC	72.838	Gain
CMGC_GSK_GSK3A_ST	Q9Y6Q9	NCOA3	P49840	GSK3A	S636	R632W	632	Missense	distal	-4	no	85.951	80.340	EPSD	COSMIC	72.838	Down-regulation
CMGC_GSK_GSK3A_ST	Q9Y6Q9	NCOA3	P49840	GSK3A	S636	S636F	636	Missense	central	0	yes	85.951	0.000	EPSD	COSMIC	72.838	Loss
CMGC_GSK_GSK3A_ST	Q9Y6Q9	NCOA3	P49840	GSK3A	S640	S636F	636	Missense	distal	-4	no	93.688	85.930	EPSD	COSMIC	72.838	Down-regulation
CMGC_GSK_GSK3A_ST	Q9Y6Q9	NCOA3	P49840	GSK3A	S655	E648K	648	Missense	distal	-7	no	84.747	85.336	EPSD	COSMIC	72.838	Up-regulation
CMGC_GSK_GSK3A_ST	Q9Y6Q9	NCOA3	P49840	GSK3A	S694	I701L	701	Missense	distal	7	no	83.545	83.029	EPSD	COSMIC	72.838	Down-regulation
CMGC_GSK_GSK3A_ST	Q9Y6Q9	NCOA3	P49840	GSK3A	S694	A696S	696	Missense	proximal	2	no	83.545	83.809	EPSD	COSMIC	72.838	Up-regulation
CMGC_GSK_GSK3A_ST	Q9Y6Q9	NCOA3	P49840	GSK3A	S694	L689P	689	Missense	distal	-5	no	83.545	85.109	EPSD	COSMIC	72.838	Up-regulation
CMGC_GSK_GSK3A_ST	Q9Y6Q9	NCOA3	P49840	GSK3A	S694	L688V	688	Missense	distal	-6	no	83.545	84.398	EPSD	COSMIC	72.838	Up-regulation
CMGC_GSK_GSK3A_ST	Q9Y6Q9	NCOA3	P49840	GSK3A	T702	I701L	701	Missense	proximal	-1	no	72.140	73.098	EPSD	COSMIC	72.838	Gain
CMGC_GSK_GSK3A_ST	Q9Y6Q9	NCOA3	P49840	GSK3A	S728	Q726H	726	Missense	proximal	-2	no	86.863	86.734	EPSD	COSMIC	72.838	Down-regulation
CMGC_GSK_GSK3A_ST	Q9Y6Q9	NCOA3	P49840	GSK3A	S767	N764Y	764	Missense	distal	-3	no	80.745	82.447	EPSD	COSMIC	72.838	Up-regulation
CMGC_GSK_GSK3A_ST	Q9Y6Q9	NCOA3	P49840	GSK3A	T770	N764Y	764	Missense	distal	-6	no	74.232	73.610	EPSD	COSMIC	72.838	Down-regulation
CMGC_GSK_GSK3A_ST	Q9Y6Q9	NCOA3	P49840	GSK3A	S777	P783L	783	Missense	distal	6	no	74.236	71.356	EPSD	COSMIC	72.838	Loss
CMGC_GSK_GSK3A_ST	Q9Y6Q9	NCOA3	P49840	GSK3A	S778	I785S	785	Missense	distal	7	no	78.542	78.647	EPSD	COSMIC	72.838	Up-regulation
CMGC_GSK_GSK3A_ST	Q9Y6Q9	NCOA3	P49840	GSK3A	S778	P783L	783	Missense	distal	5	no	78.542	69.368	EPSD	COSMIC	72.838	Loss
CMGC_GSK_GSK3A_ST	Q9Y6Q9	NCOA3	P49840	GSK3A	S860	S867C	867	Missense	distal	7	no	78.889	78.077	EPSD	COSMIC	72.838	Down-regulation
CMGC_GSK_GSK3A_ST	Q9Y6Q9	NCOA3	P49840	GSK3A	S860	S863F	863	Missense	distal	3	no	78.889	75.522	EPSD	COSMIC	72.838	Down-regulation
CMGC_GSK_GSK3A_ST	Q9Y6Q9	NCOA3	P49840	GSK3A	S860	G865D	865	Missense	distal	5	no	78.889	77.611	EPSD	COSMIC	72.838	Down-regulation
CMGC_GSK_GSK3A_ST	Q9Y6Q9	NCOA3	P49840	GSK3A	S860	S857C	857	Missense	distal	-3	no	78.889	78.003	EPSD	COSMIC	72.838	Down-regulation
CMGC_GSK_GSK3A_ST	Q9Y6Q9	NCOA3	P49840	GSK3A	S863	S867C	867	Missense	distal	4	no	76.591	3.178	EPSD	COSMIC	72.838	Loss
CMGC_GSK_GSK3A_ST	Q9Y6Q9	NCOA3	P49840	GSK3A	S863	S863F	863	Missense	central	0	yes	76.591	0.000	EPSD	COSMIC	72.838	Loss
CMGC_GSK_GSK3A_ST	Q9Y6Q9	NCOA3	P49840	GSK3A	S863	G865D	865	Missense	proximal	2	no	76.591	74.726	EPSD	COSMIC	72.838	Down-regulation
CMGC_GSK_GSK3A_ST	Q9Y6Q9	NCOA3	P49840	GSK3A	S863	S857C	857	Missense	distal	-6	no	76.591	77.187	EPSD	COSMIC	72.838	Up-regulation
CMGC_GSK_GSK3A_ST	Q9Y6Q9	NCOA3	P49840	GSK3A	T912	D919V	919	Missense	distal	7	no	72.944	73.187	EPSD	COSMIC	72.838	Up-regulation
CMGC_GSK_GSK3A_ST	Q9Y6Q9	NCOA3	P49840	GSK3A	S1330	S1330G	1330	Missense	central	0	yes	83.229	0.000	EPSD	COSMIC	72.838	Loss
CMGC_GSK_GSK3A_ST	Q9Y6Q9	NCOA3	P49840	GSK3A	S1330	P1331L	1331	Missense	proximal	1	no	83.229	69.177	EPSD	COSMIC	72.838	Loss
CMGC_GSK_GSK3A_ST	Q92597	NDRG1	P49840	GSK3A	T321	R325Q	325	Missense	distal	4	no	77.377	72.758	EPSD	COSMIC	72.838	Loss
CMGC_GSK_GSK3A_ST	Q92597	NDRG1	P49840	GSK3A	T321	Y314C	314	Missense	distal	-7	no	77.377	75.054	EPSD	COSMIC	72.838	Down-regulation
CMGC_GSK_GSK3A_ST	Q92597	NDRG1	P49840	GSK3A	T321	M315L	315	Missense	distal	-6	no	77.377	76.763	EPSD	COSMIC	72.838	Down-regulation
CMGC_GSK_GSK3A_ST	Q92597	NDRG1	P49840	GSK3A	S326	R325Q	325	Missense	proximal	-1	no	76.030	77.203	EPSD	COSMIC	72.838	Up-regulation
CMGC_GSK_GSK3A_ST	Q92597	NDRG1	P49840	GSK3A	T350	S352I	352	Missense	proximal	2	no	81.847	79.479	EPSD	COSMIC	72.838	Down-regulation
CMGC_GSK_GSK3A_ST	Q92597	NDRG1	P49840	GSK3A	T350	H355Y	355	Missense	distal	5	no	81.847	87.134	EPSD	COSMIC	72.838	Up-regulation
CMGC_GSK_GSK3A_ST	Q92597	NDRG1	P49840	GSK3A	S352	S352I	352	Missense	central	0	yes	90.406	0.000	EPSD;PhosphoSitePlus	COSMIC	72.838	Loss
CMGC_GSK_GSK3A_ST	Q92597	NDRG1	P49840	GSK3A	S352	H355Y	355	Missense	distal	3	no	90.406	90.004	EPSD;PhosphoSitePlus	COSMIC	72.838	Down-regulation
CMGC_GSK_GSK3A_ST	Q92597	NDRG1	P49840	GSK3A	T356	R361S	361	Missense	distal	5	no	82.016	81.603	EPSD	COSMIC	72.838	Down-regulation
CMGC_GSK_GSK3A_ST	Q92597	NDRG1	P49840	GSK3A	T356	R361H	361	Missense	distal	5	no	82.016	75.520	EPSD	COSMIC;CCLE	72.838	Down-regulation
CMGC_GSK_GSK3A_ST	Q92597	NDRG1	P49840	GSK3A	T356	S352I	352	Missense	distal	-4	no	82.016	76.231	EPSD	COSMIC	72.838	Down-regulation
CMGC_GSK_GSK3A_ST	Q92597	NDRG1	P49840	GSK3A	T356	H355Y	355	Missense	proximal	-1	no	82.016	83.186	EPSD	COSMIC	72.838	Up-regulation
CMGC_GSK_GSK3A_ST	Q92597	NDRG1	P49840	GSK3A	S357	R361S	361	Missense	distal	4	no	74.964	84.359	EPSD	COSMIC	72.838	Up-regulation
CMGC_GSK_GSK3A_ST	Q92597	NDRG1	P49840	GSK3A	S357	R361H	361	Missense	distal	4	no	74.964	56.322	EPSD	COSMIC;CCLE	72.838	Loss
CMGC_GSK_GSK3A_ST	Q92597	NDRG1	P49840	GSK3A	S357	S352I	352	Missense	distal	-5	no	74.964	73.041	EPSD	COSMIC	72.838	Down-regulation
CMGC_GSK_GSK3A_ST	Q92597	NDRG1	P49840	GSK3A	S357	H355Y	355	Missense	proximal	-2	no	74.964	75.105	EPSD	COSMIC	72.838	Up-regulation
CMGC_GSK_GSK3A_ST	Q92597	NDRG1	P49840	GSK3A	T360	R361S	361	Missense	proximal	1	no	78.647	71.608	EPSD	COSMIC	72.838	Loss
CMGC_GSK_GSK3A_ST	Q92597	NDRG1	P49840	GSK3A	T360	R361H	361	Missense	proximal	1	no	78.647	60.886	EPSD	COSMIC;CCLE	72.838	Loss
CMGC_GSK_GSK3A_ST	Q92597	NDRG1	P49840	GSK3A	T360	H355Y	355	Missense	distal	-5	no	78.647	78.955	EPSD	COSMIC	72.838	Up-regulation
CMGC_GSK_GSK3A_ST	Q92597	NDRG1	P49840	GSK3A	T360	H365Y	365	Missense	distal	5	no	78.647	83.934	EPSD	COSMIC	72.838	Up-regulation
CMGC_GSK_GSK3A_ST	Q92597	NDRG1	P49840	GSK3A	S362	R361S	361	Missense	proximal	-1	no	86.523	86.821	EPSD;PhosphoSitePlus	COSMIC	72.838	Up-regulation
CMGC_GSK_GSK3A_ST	Q92597	NDRG1	P49840	GSK3A	S362	R361H	361	Missense	proximal	-1	no	86.523	86.972	EPSD;PhosphoSitePlus	COSMIC;CCLE	72.838	Up-regulation
CMGC_GSK_GSK3A_ST	Q92597	NDRG1	P49840	GSK3A	S362	H355Y	355	Missense	distal	-7	no	86.523	86.106	EPSD;PhosphoSitePlus	COSMIC	72.838	Down-regulation
CMGC_GSK_GSK3A_ST	Q92597	NDRG1	P49840	GSK3A	S362	H365Y	365	Missense	distal	3	no	86.523	86.121	EPSD;PhosphoSitePlus	COSMIC	72.838	Down-regulation
CMGC_GSK_GSK3A_ST	Q92597	NDRG1	P49840	GSK3A	S364	H365Y	365	Missense	proximal	1	no	69.232	88.037	EPSD	COSMIC	72.838	Gain
CMGC_GSK_GSK3A_ST	P31749	AKT1	P49840	GSK3A	S122	E115K	115	Missense	distal	-7	no	77.174	77.763	EPSD	COSMIC	72.838	Up-regulation
CMGC_GSK_GSK3A_ST	P31749	AKT1	P49840	GSK3A	S122	G123D	123	Missense	proximal	1	no	77.174	67.005	EPSD	COSMIC	72.838	Loss
CMGC_GSK_GSK3A_ST	P31749	AKT1	P49840	GSK3A	S122	D127N	127	Missense	distal	5	no	77.174	56.719	EPSD	COSMIC	72.838	Loss
CMGC_GSK_GSK3A_ST	P31749	AKT1	P49840	GSK3A	S122	E116D	116	Missense	distal	-6	no	77.174	78.808	EPSD	COSMIC	72.838	Up-regulation
CMGC_GSK_GSK3A_ST	P31749	AKT1	P49840	GSK3A	S129	G123D	123	Missense	distal	-6	no	76.993	78.014	EPSD	COSMIC	72.838	Up-regulation
CMGC_GSK_GSK3A_ST	P31749	AKT1	P49840	GSK3A	S129	D127N	127	Missense	proximal	-2	no	76.993	76.994	EPSD	COSMIC	72.838	Up-regulation
CMGC_GSK_GSK3A_ST	P31749	AKT1	P49840	GSK3A	S129	E133Q	133	Missense	distal	4	no	76.993	66.938	EPSD	COSMIC	72.838	Loss
CMGC_GSK_GSK3A_ST	P31749	AKT1	P49840	GSK3A	S129	G130R	130	Missense	proximal	1	no	76.993	78.816	EPSD	COSMIC	72.838	Up-regulation
CMGC_GSK_GSK3A_ST	P31749	AKT1	P49840	GSK3A	S129	E135Q	135	Missense	distal	6	no	76.993	78.912	EPSD	COSMIC	72.838	Up-regulation
CMGC_GSK_GSK3A_ST	P31749	AKT1	P49840	GSK3A	T312	M306T	306	Missense	distal	-6	no	84.746	84.078	EPSD;PhosphoSitePlus	COSMIC	72.838	Down-regulation
CMGC_GSK_GSK3A_ST	P31749	AKT1	P49840	GSK3A	T312	M306L	306	Missense	distal	-6	no	84.746	84.131	EPSD;PhosphoSitePlus	COSMIC	72.838	Down-regulation
CMGC_GSK_GSK3A_ST	P31749	AKT1	P49840	GSK3A	T312	M306I	306	Missense	distal	-6	no	84.746	84.538	EPSD;PhosphoSitePlus	COSMIC	72.838	Down-regulation
CMGC_GSK_GSK3A_ST	P31749	AKT1	P49840	GSK3A	T312	T312I	312	Missense	central	0	yes	84.746	0.000	EPSD;PhosphoSitePlus	COSMIC	72.838	Loss
CMGC_GSK_GSK3A_ST	P31749	AKT1	P49840	GSK3A	S422	V416M	416	Missense	distal	-6	no	74.281	74.043	EPSD	COSMIC	72.838	Down-regulation
CMGC_GSK_GSK3A_ST	P31749	AKT1	P49840	GSK3A	S422	S422R	422	Missense	central	0	yes	74.281	0.000	EPSD	COSMIC	72.838	Loss
CMGC_GSK_GSK3A_ST	P31749	AKT1	P49840	GSK3A	T443	M446I	446	Missense	distal	3	no	75.141	75.746	EPSD	COSMIC	72.838	Up-regulation
CMGC_GSK_GSK3A_ST	P31749	AKT1	P49840	GSK3A	T443	I447F	447	Missense	distal	4	no	75.141	56.924	EPSD	COSMIC	72.838	Loss
CMGC_GSK_GSK3A_ST	P31749	AKT1	P49840	GSK3A	T443	T443M	443	Missense	central	0	yes	75.141	0.000	EPSD	COSMIC	72.838	Loss
CMGC_GSK_GSK3A_ST	Q16584	MAP3K11	P49840	GSK3A	S35	R31W	31	Missense	distal	-4	no	84.846	79.235	EPSD	COSMIC	72.838	Down-regulation
CMGC_GSK_GSK3A_ST	Q16584	MAP3K11	P49840	GSK3A	T277	A283T	283	Missense	distal	6	no	70.975	73.701	EPSD	COSMIC	72.838	Gain
CMGC_GSK_GSK3A_ST	Q16584	MAP3K11	P49840	GSK3A	T277	R272Q	272	Missense	distal	-5	no	70.975	73.324	EPSD	COSMIC	72.838	Gain
CMGC_GSK_GSK3A_ST	Q16584	MAP3K11	P49840	GSK3A	S507	T503A	503	Missense	distal	-4	no	83.004	77.248	EPSD	COSMIC	72.838	Down-regulation
CMGC_GSK_GSK3A_ST	Q16584	MAP3K11	P49840	GSK3A	S507	H500R	500	Missense	distal	-7	no	83.004	80.937	EPSD	COSMIC	72.838	Down-regulation
CMGC_GSK_GSK3A_ST	Q16584	MAP3K11	P49840	GSK3A	S507	R501C	501	Missense	distal	-6	no	83.004	83.212	EPSD	COSMIC	72.838	Up-regulation
CMGC_GSK_GSK3A_ST	Q16584	MAP3K11	P49840	GSK3A	S674	T680M	680	Missense	distal	6	no	89.853	88.455	EPSD	COSMIC	72.838	Down-regulation
CMGC_GSK_GSK3A_ST	Q16584	MAP3K11	P49840	GSK3A	S674	G672R	672	Missense	proximal	-2	no	89.853	90.956	EPSD	COSMIC	72.838	Up-regulation
CMGC_GSK_GSK3A_ST	Q16584	MAP3K11	P49840	GSK3A	S674	R671H	671	Missense	distal	-3	no	89.853	90.583	EPSD	COSMIC	72.838	Up-regulation
CMGC_GSK_GSK3A_ST	Q16584	MAP3K11	P49840	GSK3A	S674	P679L	679	Missense	distal	5	no	89.853	80.680	EPSD	COSMIC	72.838	Down-regulation
CMGC_GSK_GSK3A_ST	Q16584	MAP3K11	P49840	GSK3A	S674	P667S	667	Missense	distal	-7	no	89.853	89.698	EPSD	COSMIC	72.838	Down-regulation
CMGC_GSK_GSK3A_ST	Q16584	MAP3K11	P49840	GSK3A	T677	T680M	680	Missense	distal	3	no	82.147	78.819	EPSD	COSMIC	72.838	Down-regulation
CMGC_GSK_GSK3A_ST	Q16584	MAP3K11	P49840	GSK3A	T677	G672R	672	Missense	distal	-5	no	82.147	80.658	EPSD	COSMIC	72.838	Down-regulation
CMGC_GSK_GSK3A_ST	Q16584	MAP3K11	P49840	GSK3A	T677	R671H	671	Missense	distal	-6	no	82.147	81.923	EPSD	COSMIC	72.838	Down-regulation
CMGC_GSK_GSK3A_ST	Q16584	MAP3K11	P49840	GSK3A	T677	P683S	683	Missense	distal	6	no	82.147	81.597	EPSD	COSMIC	72.838	Down-regulation
CMGC_GSK_GSK3A_ST	Q16584	MAP3K11	P49840	GSK3A	T677	P679L	679	Missense	proximal	2	no	82.147	81.438	EPSD	COSMIC	72.838	Down-regulation
CMGC_GSK_GSK3A_ST	Q16584	MAP3K11	P49840	GSK3A	T677	P683L	683	Missense	distal	6	no	82.147	79.267	EPSD	COSMIC	72.838	Down-regulation
CMGC_GSK_GSK3A_ST	Q16584	MAP3K11	P49840	GSK3A	T680	T680M	680	Missense	central	0	yes	93.279	0.000	EPSD	COSMIC	72.838	Loss
CMGC_GSK_GSK3A_ST	Q16584	MAP3K11	P49840	GSK3A	T680	P683S	683	Missense	distal	3	no	93.279	91.947	EPSD	COSMIC	72.838	Down-regulation
CMGC_GSK_GSK3A_ST	Q16584	MAP3K11	P49840	GSK3A	T680	P679L	679	Missense	proximal	-1	no	93.279	92.125	EPSD	COSMIC	72.838	Down-regulation
CMGC_GSK_GSK3A_ST	Q16584	MAP3K11	P49840	GSK3A	T680	P683L	683	Missense	distal	3	no	93.279	89.419	EPSD	COSMIC	72.838	Down-regulation
CMGC_GSK_GSK3A_ST	Q16584	MAP3K11	P49840	GSK3A	S705	T702M	702	Missense	distal	-3	no	79.758	78.689	EPSD	COSMIC	72.838	Down-regulation
CMGC_GSK_GSK3A_ST	Q16584	MAP3K11	P49840	GSK3A	S705	D704A	704	Missense	proximal	-1	no	79.758	81.173	EPSD	COSMIC	72.838	Up-regulation
CMGC_GSK_GSK3A_ST	Q16584	MAP3K11	P49840	GSK3A	T708	T702M	702	Missense	distal	-6	no	82.975	83.643	EPSD	COSMIC	72.838	Up-regulation
CMGC_GSK_GSK3A_ST	Q16584	MAP3K11	P49840	GSK3A	T708	D704A	704	Missense	distal	-4	no	82.975	79.708	EPSD	COSMIC	72.838	Down-regulation
CMGC_GSK_GSK3A_ST	Q16584	MAP3K11	P49840	GSK3A	S724	R730H	730	Missense	distal	6	no	71.948	73.429	EPSD	COSMIC	72.838	Gain
CMGC_GSK_GSK3A_ST	Q16584	MAP3K11	P49840	GSK3A	S727	R730H	730	Missense	distal	3	no	86.287	90.298	EPSD	COSMIC	72.838	Up-regulation
CMGC_GSK_GSK3A_ST	Q16584	MAP3K11	P49840	GSK3A	S727	Q722L	722	Missense	distal	-5	no	86.287	83.961	EPSD	COSMIC	72.838	Down-regulation
CMGC_GSK_GSK3A_ST	Q16584	MAP3K11	P49840	GSK3A	T745	P750S	750	Missense	distal	5	no	79.217	73.660	EPSD	COSMIC	72.838	Down-regulation
CMGC_GSK_GSK3A_ST	Q16584	MAP3K11	P49840	GSK3A	S746	P750S	750	Missense	distal	4	no	83.571	89.557	EPSD	COSMIC	72.838	Up-regulation
CMGC_GSK_GSK3A_ST	Q16584	MAP3K11	P49840	GSK3A	S748	P750S	750	Missense	proximal	2	no	82.960	82.271	EPSD	COSMIC	72.838	Down-regulation
CMGC_GSK_GSK3A_ST	Q16584	MAP3K11	P49840	GSK3A	T752	P750S	750	Missense	proximal	-2	no	83.041	82.889	EPSD	COSMIC	72.838	Down-regulation
CMGC_GSK_GSK3A_ST	Q16584	MAP3K11	P49840	GSK3A	T755	G762V	762	Missense	distal	7	no	84.778	83.584	EPSD	COSMIC	72.838	Down-regulation
CMGC_GSK_GSK3A_ST	Q16584	MAP3K11	P49840	GSK3A	T755	P750S	750	Missense	distal	-5	no	84.778	84.864	EPSD	COSMIC	72.838	Up-regulation
CMGC_GSK_GSK3A_ST	Q16584	MAP3K11	P49840	GSK3A	S758	G762V	762	Missense	distal	4	no	65.162	77.121	EPSD	COSMIC	72.838	Gain
CMGC_GSK_GSK3A_ST	Q16584	MAP3K11	P49840	GSK3A	S770	L772F	772	Missense	proximal	2	no	87.604	84.031	EPSD	COSMIC	72.838	Down-regulation
CMGC_GSK_GSK3A_ST	Q16584	MAP3K11	P49840	GSK3A	S770	R773H	773	Missense	distal	3	no	87.604	91.615	EPSD	COSMIC	72.838	Up-regulation
CMGC_GSK_GSK3A_ST	Q16584	MAP3K11	P49840	GSK3A	S783	P786S	786	Missense	distal	3	no	80.056	78.723	EPSD	COSMIC	72.838	Down-regulation
CMGC_GSK_GSK3A_ST	Q16584	MAP3K11	P49840	GSK3A	S789	P786S	786	Missense	distal	-3	no	103.622	102.982	PhosphoSitePlus;EPSD	COSMIC	72.838	Down-regulation
CMGC_GSK_GSK3A_ST	Q16584	MAP3K11	P49840	GSK3A	S793	P786S	786	Missense	distal	-7	no	89.990	89.835	EPSD;PhosphoSitePlus	COSMIC	72.838	Down-regulation
CMGC_GSK_GSK3A_ST	Q16584	MAP3K11	P49840	GSK3A	S793	R799C	799	Missense	distal	6	no	89.990	85.827	EPSD;PhosphoSitePlus	COSMIC	72.838	Down-regulation
CMGC_GSK_GSK3A_ST	Q16584	MAP3K11	P49840	GSK3A	S815	D808E	808	Missense	distal	-7	no	76.751	78.244	EPSD	COSMIC	72.838	Up-regulation
CMGC_GSK_GSK3A_ST	Q16584	MAP3K11	P49840	GSK3A	S815	D810H	810	Missense	distal	-5	no	76.751	78.385	EPSD	COSMIC;GDSC	72.838	Up-regulation
CMGC_GSK_GSK3A_ST	O75030	MITF	P49840	GSK3A	S55	I57F	57	Missense	proximal	2	no	75.212	73.987	EPSD	COSMIC	72.838	Down-regulation
CMGC_GSK_GSK3A_ST	O75030	MITF	P49840	GSK3A	S55	I48T	48	Missense	distal	-7	no	75.212	76.858	EPSD	COSMIC	72.838	Up-regulation
CMGC_GSK_GSK3A_ST	O75030	MITF	P49840	GSK3A	S55	S52N	52	Missense	distal	-3	no	75.212	74.370	EPSD	COSMIC	72.838	Down-regulation
CMGC_GSK_GSK3A_ST	O75030	MITF	P49840	GSK3A	S55	S51N	51	Missense	distal	-4	no	75.212	72.639	EPSD	COSMIC	72.838	Loss
CMGC_GSK_GSK3A_ST	O75030	MITF	P49840	GSK3A	S55	S50F	50	Missense	distal	-5	no	75.212	69.845	EPSD	COSMIC	72.838	Loss
CMGC_GSK_GSK3A_ST	O75030	MITF	P49840	GSK3A	S176	A177V	177	Missense	proximal	1	no	73.322	63.499	EPSD	COSMIC	72.838	Loss
CMGC_GSK_GSK3A_ST	O75030	MITF	P49840	GSK3A	S176	N179I	179	Missense	distal	3	no	73.322	69.937	EPSD	COSMIC	72.838	Loss
CMGC_GSK_GSK3A_ST	O75030	MITF	P49840	GSK3A	S176	P170L	170	Missense	distal	-6	no	73.322	73.448	EPSD	COSMIC	72.838	Up-regulation
CMGC_GSK_GSK3A_ST	O75030	MITF	P49840	GSK3A	S176	P170S	170	Missense	distal	-6	no	73.322	73.267	EPSD	COSMIC	72.838	Down-regulation
CMGC_GSK_GSK3A_ST	O75030	MITF	P49840	GSK3A	S180	A177V	177	Missense	distal	-3	no	76.843	76.648	EPSD	COSMIC	72.838	Down-regulation
CMGC_GSK_GSK3A_ST	O75030	MITF	P49840	GSK3A	S180	N179I	179	Missense	proximal	-1	no	76.843	76.215	EPSD	COSMIC	72.838	Down-regulation
CMGC_GSK_GSK3A_ST	O75030	MITF	P49840	GSK3A	S405	L406H	406	Missense	proximal	1	no	82.930	70.568	EPSD	COSMIC	72.838	Loss
CMGC_GSK_GSK3A_ST	O75030	MITF	P49840	GSK3A	S405	A399D	399	Missense	distal	-6	no	82.930	83.471	EPSD	COSMIC	72.838	Up-regulation
CMGC_GSK_GSK3A_ST	O75030	MITF	P49840	GSK3A	S405	S405I	405	Missense	central	0	yes	82.930	0.000	EPSD	COSMIC	72.838	Loss
CMGC_GSK_GSK3A_ST	O75030	MITF	P49840	GSK3A	S405	R400W	400	Missense	distal	-5	no	82.930	83.159	EPSD	COSMIC	72.838	Up-regulation
CMGC_GSK_GSK3A_ST	O75030	MITF	P49840	GSK3A	S491	V493I	493	Missense	proximal	2	no	78.972	77.685	EPSD	COSMIC	72.838	Down-regulation
CMGC_GSK_GSK3A_ST	O75030	MITF	P49840	GSK3A	S491	D487N	487	Missense	distal	-4	no	78.972	78.079	EPSD	COSMIC	72.838	Down-regulation
CMGC_GSK_GSK3A_ST	O75030	MITF	P49840	GSK3A	S491	T489N	489	Missense	proximal	-2	no	78.972	78.504	EPSD	COSMIC	72.838	Down-regulation
CMGC_GSK_GSK3A_ST	O75030	MITF	P49840	GSK3A	S504	S504F	504	Missense	central	0	yes	80.561	0.000	EPSD	COSMIC	72.838	Loss
CMGC_GSK_GSK3A_ST	O75030	MITF	P49840	GSK3A	S504	A507T	507	Missense	distal	3	no	80.561	81.941	EPSD	COSMIC	72.838	Up-regulation
CMGC_GSK_GSK3A_ST	O75030	MITF	P49840	GSK3A	S504	S511I	511	Missense	distal	7	no	80.561	80.455	EPSD	COSMIC	72.838	Down-regulation
CMGC_GSK_GSK3A_ST	O75030	MITF	P49840	GSK3A	S508	S512I	512	Missense	distal	4	no	81.179	77.106	EPSD	COSMIC	72.838	Down-regulation
CMGC_GSK_GSK3A_ST	O75030	MITF	P49840	GSK3A	S508	S504F	504	Missense	distal	-4	no	81.179	73.420	EPSD	COSMIC	72.838	Down-regulation
CMGC_GSK_GSK3A_ST	O75030	MITF	P49840	GSK3A	S508	A507T	507	Missense	proximal	-1	no	81.179	82.088	EPSD	COSMIC	72.838	Up-regulation
CMGC_GSK_GSK3A_ST	O75030	MITF	P49840	GSK3A	S508	R513W	513	Missense	distal	5	no	81.179	56.117	EPSD	COSMIC	72.838	Loss
CMGC_GSK_GSK3A_ST	O75030	MITF	P49840	GSK3A	S508	S511I	511	Missense	distal	3	no	81.179	80.478	EPSD	COSMIC	72.838	Down-regulation
CMGC_GSK_GSK3A_ST	P24864	CCNE1	P49840	GSK3A	S73	D79N	79	Missense	distal	6	no	79.146	80.738	EPSD	COSMIC	72.838	Up-regulation
CMGC_GSK_GSK3A_ST	P24864	CCNE1	P49840	GSK3A	S73	P71S	71	Missense	proximal	-2	no	79.146	78.994	EPSD	COSMIC	72.838	Down-regulation
CMGC_GSK_GSK3A_ST	P24864	CCNE1	P49840	GSK3A	S73	A69T	69	Missense	distal	-4	no	79.146	84.902	EPSD	COSMIC	72.838	Up-regulation
CMGC_GSK_GSK3A_ST	P24864	CCNE1	P49840	GSK3A	S73	A69V	69	Missense	distal	-4	no	79.146	78.315	EPSD	COSMIC	72.838	Down-regulation
CMGC_GSK_GSK3A_ST	P24864	CCNE1	P49840	GSK3A	S73	C68F	68	Missense	distal	-5	no	79.146	76.136	EPSD	COSMIC;GDSC;CCLE	72.838	Down-regulation
CMGC_GSK_GSK3A_ST	P24864	CCNE1	P49840	GSK3A	S73	P76L	76	Missense	distal	3	no	79.146	75.286	EPSD	COSMIC	72.838	Down-regulation
CMGC_GSK_GSK3A_ST	P24864	CCNE1	P49840	GSK3A	S73	A69S	69	Missense	distal	-4	no	79.146	84.093	EPSD	COSMIC;CCLE	72.838	Up-regulation
CMGC_GSK_GSK3A_ST	P24864	CCNE1	P49840	GSK3A	S103	V107L	107	Missense	distal	4	no	79.511	79.681	EPSD	COSMIC;CCLE	72.838	Up-regulation
CMGC_GSK_GSK3A_ST	P24864	CCNE1	P49840	GSK3A	S387	L389F	389	Missense	proximal	2	no	74.609	71.037	EPSD	COSMIC	72.838	Loss
CMGC_GSK_GSK3A_ST	P24864	CCNE1	P49840	GSK3A	S387	S381C	381	Missense	distal	-6	no	74.609	75.205	EPSD	COSMIC	72.838	Up-regulation
CMGC_GSK_GSK3A_ST	P24864	CCNE1	P49840	GSK3A	S387	S391R	391	Missense	distal	4	no	74.609	65.214	EPSD	COSMIC	72.838	Loss
CMGC_GSK_GSK3A_ST	P24864	CCNE1	P49840	GSK3A	S387	A386V	386	Missense	proximal	-1	no	74.609	74.068	EPSD	COSMIC	72.838	Down-regulation
CMGC_GSK_GSK3A_ST	P24864	CCNE1	P49840	GSK3A	S387	N384K	384	Missense	distal	-3	no	74.609	74.800	EPSD	COSMIC;GDSC;CCLE	72.838	Up-regulation
CMGC_GSK_GSK3A_ST	P24864	CCNE1	P49840	GSK3A	S391	L389F	389	Missense	proximal	-2	no	89.096	88.593	EPSD	COSMIC	72.838	Down-regulation
CMGC_GSK_GSK3A_ST	P24864	CCNE1	P49840	GSK3A	S391	S391R	391	Missense	central	0	yes	89.096	0.000	EPSD	COSMIC	72.838	Loss
CMGC_GSK_GSK3A_ST	P24864	CCNE1	P49840	GSK3A	S391	T395P	395	Missense	distal	4	no	89.096	83.610	EPSD	COSMIC	72.838	Down-regulation
CMGC_GSK_GSK3A_ST	P24864	CCNE1	P49840	GSK3A	S391	A386V	386	Missense	distal	-5	no	89.096	87.910	EPSD	COSMIC	72.838	Down-regulation
CMGC_GSK_GSK3A_ST	P24864	CCNE1	P49840	GSK3A	S391	N384K	384	Missense	distal	-7	no	89.096	89.478	EPSD	COSMIC;GDSC;CCLE	72.838	Up-regulation
CMGC_GSK_GSK3A_ST	P24864	CCNE1	P49840	GSK3A	T395	L389F	389	Missense	distal	-6	no	86.429	87.879	PhosphoSitePlus	COSMIC	72.838	Up-regulation
CMGC_GSK_GSK3A_ST	P24864	CCNE1	P49840	GSK3A	T395	S391R	391	Missense	distal	-4	no	86.429	83.061	PhosphoSitePlus	COSMIC	72.838	Down-regulation
CMGC_GSK_GSK3A_ST	P24864	CCNE1	P49840	GSK3A	T395	T395P	395	Missense	central	0	yes	86.429	0.000	PhosphoSitePlus	COSMIC	72.838	Loss
CMGC_GSK_GSK3A_ST	Q6R327	RICTOR	P49840	GSK3A	T258	D259G	259	Missense	proximal	1	no	73.543	83.713	EPSD	COSMIC	72.838	Up-regulation
CMGC_GSK_GSK3A_ST	Q6R327	RICTOR	P49840	GSK3A	T258	H261N	261	Missense	distal	3	no	73.543	71.930	EPSD	COSMIC	72.838	Loss
CMGC_GSK_GSK3A_ST	Q6R327	RICTOR	P49840	GSK3A	S265	D259G	259	Missense	distal	-6	no	76.825	75.804	EPSD	COSMIC	72.838	Down-regulation
CMGC_GSK_GSK3A_ST	Q6R327	RICTOR	P49840	GSK3A	S265	H261N	261	Missense	distal	-4	no	76.825	74.656	EPSD	COSMIC	72.838	Down-regulation
CMGC_GSK_GSK3A_ST	Q6R327	RICTOR	P49840	GSK3A	T852	L847F	847	Missense	distal	-5	no	80.670	76.953	EPSD	COSMIC	72.838	Down-regulation
CMGC_GSK_GSK3A_ST	Q6R327	RICTOR	P49840	GSK3A	T852	R855W	855	Missense	distal	3	no	80.670	73.061	EPSD	COSMIC	72.838	Down-regulation
CMGC_GSK_GSK3A_ST	Q6R327	RICTOR	P49840	GSK3A	T852	D859H	859	Missense	distal	7	no	80.670	81.959	EPSD	COSMIC	72.838	Up-regulation
CMGC_GSK_GSK3A_ST	Q6R327	RICTOR	P49840	GSK3A	T852	E845K	845	Missense	distal	-7	no	80.670	81.259	EPSD	COSMIC	72.838	Up-regulation
CMGC_GSK_GSK3A_ST	Q6R327	RICTOR	P49840	GSK3A	T852	L847P	847	Missense	distal	-5	no	80.670	82.234	EPSD	COSMIC	72.838	Up-regulation
CMGC_GSK_GSK3A_ST	Q6R327	RICTOR	P49840	GSK3A	T853	L847F	847	Missense	distal	-6	no	73.267	74.717	EPSD	COSMIC	72.838	Up-regulation
CMGC_GSK_GSK3A_ST	Q6R327	RICTOR	P49840	GSK3A	T853	R855W	855	Missense	proximal	2	no	73.267	69.788	EPSD	COSMIC	72.838	Loss
CMGC_GSK_GSK3A_ST	Q6R327	RICTOR	P49840	GSK3A	T853	D859H	859	Missense	distal	6	no	73.267	76.391	EPSD	COSMIC	72.838	Up-regulation
CMGC_GSK_GSK3A_ST	Q6R327	RICTOR	P49840	GSK3A	T853	L847P	847	Missense	distal	-6	no	73.267	73.141	EPSD	COSMIC	72.838	Down-regulation
CMGC_GSK_GSK3A_ST	Q6R327	RICTOR	P49840	GSK3A	S1030	T1029A	1029	Missense	proximal	-1	no	85.491	84.582	EPSD	COSMIC	72.838	Down-regulation
CMGC_GSK_GSK3A_ST	Q6R327	RICTOR	P49840	GSK3A	S1031	T1029A	1029	Missense	proximal	-2	no	85.403	85.517	EPSD	COSMIC	72.838	Up-regulation
CMGC_GSK_GSK3A_ST	Q6R327	RICTOR	P49840	GSK3A	S1035	P1041S	1041	Missense	distal	6	no	73.166	72.616	EPSD	COSMIC;GDSC;CCLE	72.838	Loss
CMGC_GSK_GSK3A_ST	Q6R327	RICTOR	P49840	GSK3A	S1035	T1029A	1029	Missense	distal	-6	no	73.166	73.748	EPSD	COSMIC	72.838	Up-regulation
CMGC_GSK_GSK3A_ST	Q6R327	RICTOR	P49840	GSK3A	S1039	P1041S	1041	Missense	proximal	2	no	72.949	72.260	EPSD	COSMIC;GDSC;CCLE	72.838	Loss
CMGC_GSK_GSK3A_ST	Q6R327	RICTOR	P49840	GSK3A	S1121	P1115A	1115	Missense	distal	-6	no	73.112	73.767	EPSD	COSMIC	72.838	Up-regulation
CMGC_GSK_GSK3A_ST	Q6R327	RICTOR	P49840	GSK3A	T1148	S1151C	1151	Missense	distal	3	no	83.010	78.696	EPSD	COSMIC	72.838	Down-regulation
CMGC_GSK_GSK3A_ST	Q6R327	RICTOR	P49840	GSK3A	S1217	K1214Q	1214	Missense	distal	-3	no	73.728	73.777	EPSD	COSMIC	72.838	Up-regulation
CMGC_GSK_GSK3A_ST	Q6R327	RICTOR	P49840	GSK3A	S1217	M1213L	1213	Missense	distal	-4	no	73.728	64.571	EPSD	COSMIC	72.838	Loss
CMGC_GSK_GSK3A_ST	Q6R327	RICTOR	P49840	GSK3A	S1217	Q1218P	1218	Missense	proximal	1	no	73.728	84.405	EPSD	COSMIC	72.838	Up-regulation
CMGC_GSK_GSK3A_ST	Q6R327	RICTOR	P49840	GSK3A	S1217	S1211L	1211	Missense	distal	-6	no	73.728	73.909	EPSD	COSMIC	72.838	Up-regulation
CMGC_GSK_GSK3A_ST	Q6R327	RICTOR	P49840	GSK3A	S1219	K1214Q	1214	Missense	distal	-5	no	82.371	83.951	EPSD	COSMIC	72.838	Up-regulation
CMGC_GSK_GSK3A_ST	Q6R327	RICTOR	P49840	GSK3A	S1219	M1213L	1213	Missense	distal	-6	no	82.371	81.756	EPSD	COSMIC	72.838	Down-regulation
CMGC_GSK_GSK3A_ST	Q6R327	RICTOR	P49840	GSK3A	S1219	Q1218P	1218	Missense	proximal	-1	no	82.371	82.393	EPSD	COSMIC	72.838	Up-regulation
CMGC_GSK_GSK3A_ST	Q6R327	RICTOR	P49840	GSK3A	T1222	Q1218P	1218	Missense	distal	-4	no	75.301	78.136	EPSD	COSMIC	72.838	Up-regulation
CMGC_GSK_GSK3A_ST	Q6R327	RICTOR	P49840	GSK3A	S1230	P1236A	1236	Missense	distal	6	no	77.524	74.979	EPSD	COSMIC	72.838	Down-regulation
CMGC_GSK_GSK3A_ST	Q6R327	RICTOR	P49840	GSK3A	S1233	P1236A	1236	Missense	distal	3	no	84.187	83.497	EPSD	COSMIC	72.838	Down-regulation
CMGC_GSK_GSK3A_ST	Q6R327	RICTOR	P49840	GSK3A	S1233	E1239D	1239	Missense	distal	6	no	84.187	83.408	EPSD	COSMIC	72.838	Down-regulation
CMGC_GSK_GSK3A_ST	Q6R327	RICTOR	P49840	GSK3A	S1235	P1236A	1236	Missense	proximal	1	no	93.197	79.530	EPSD	COSMIC	72.838	Down-regulation
CMGC_GSK_GSK3A_ST	Q6R327	RICTOR	P49840	GSK3A	S1235	E1239D	1239	Missense	distal	4	no	93.197	92.815	EPSD	COSMIC	72.838	Down-regulation
CMGC_GSK_GSK3A_ST	Q6R327	RICTOR	P49840	GSK3A	S1237	P1236A	1236	Missense	proximal	-1	no	73.549	73.425	EPSD	COSMIC	72.838	Down-regulation
CMGC_GSK_GSK3A_ST	Q6R327	RICTOR	P49840	GSK3A	S1237	E1239D	1239	Missense	proximal	2	no	73.549	69.649	EPSD	COSMIC	72.838	Loss
CMGC_GSK_GSK3A_ST	Q6R327	RICTOR	P49840	GSK3A	T1271	T1266K	1266	Missense	distal	-5	no	73.872	73.295	EPSD	COSMIC	72.838	Down-regulation
CMGC_GSK_GSK3A_ST	Q6R327	RICTOR	P49840	GSK3A	T1271	S1278F	1278	Missense	distal	7	no	73.872	71.453	EPSD	COSMIC	72.838	Loss
CMGC_GSK_GSK3A_ST	Q6R327	RICTOR	P49840	GSK3A	S1278	N1283S	1283	Missense	distal	5	no	56.797	78.564	EPSD	COSMIC	72.838	Gain
CMGC_GSK_GSK3A_ST	Q6R327	RICTOR	P49840	GSK3A	S1280	N1283S	1283	Missense	distal	3	no	75.233	72.549	EPSD	COSMIC	72.838	Loss
CMGC_GSK_GSK3A_ST	Q6R327	RICTOR	P49840	GSK3A	S1280	L1279P	1279	Missense	proximal	-1	no	75.233	76.388	EPSD	COSMIC;CCLE	72.838	Up-regulation
CMGC_GSK_GSK3A_ST	Q6R327	RICTOR	P49840	GSK3A	S1280	S1278F	1278	Missense	proximal	-2	no	75.233	74.014	EPSD	COSMIC	72.838	Down-regulation
CMGC_GSK_GSK3A_ST	Q6R327	RICTOR	P49840	GSK3A	S1286	N1283S	1283	Missense	distal	-3	no	83.909	84.751	EPSD	COSMIC	72.838	Up-regulation
CMGC_GSK_GSK3A_ST	Q6R327	RICTOR	P49840	GSK3A	S1286	L1279P	1279	Missense	distal	-7	no	83.909	85.740	EPSD	COSMIC;CCLE	72.838	Up-regulation
CMGC_GSK_GSK3A_ST	Q6R327	RICTOR	P49840	GSK3A	S1292	P1297S	1297	Missense	distal	5	no	74.101	68.545	EPSD	COSMIC	72.838	Loss
CMGC_GSK_GSK3A_ST	Q6R327	RICTOR	P49840	GSK3A	S1292	R1299K	1299	Missense	distal	7	no	74.101	75.260	EPSD	COSMIC	72.838	Up-regulation
CMGC_GSK_GSK3A_ST	Q6R327	RICTOR	P49840	GSK3A	S1320	C1317F	1317	Missense	distal	-3	no	91.495	91.153	EPSD	COSMIC	72.838	Down-regulation
CMGC_GSK_GSK3A_ST	Q6R327	RICTOR	P49840	GSK3A	S1320	S1323I	1323	Missense	distal	3	no	91.495	90.794	EPSD	COSMIC	72.838	Down-regulation
CMGC_GSK_GSK3A_ST	Q6R327	RICTOR	P49840	GSK3A	S1323	C1317F	1317	Missense	distal	-6	no	77.631	78.666	EPSD	COSMIC	72.838	Up-regulation
CMGC_GSK_GSK3A_ST	Q6R327	RICTOR	P49840	GSK3A	S1323	Y1330C	1330	Missense	distal	7	no	77.631	76.743	EPSD	COSMIC	72.838	Down-regulation
CMGC_GSK_GSK3A_ST	Q6R327	RICTOR	P49840	GSK3A	S1323	S1323I	1323	Missense	central	0	yes	77.631	0.000	EPSD	COSMIC	72.838	Loss
CMGC_GSK_GSK3A_ST	Q6R327	RICTOR	P49840	GSK3A	S1353	P1354L	1354	Missense	proximal	1	no	76.756	62.704	EPSD	COSMIC	72.838	Loss
CMGC_GSK_GSK3A_ST	Q6R327	RICTOR	P49840	GSK3A	S1353	F1360C	1360	Missense	distal	7	no	76.756	78.363	EPSD	COSMIC	72.838	Up-regulation
CMGC_GSK_GSK3A_ST	Q6R327	RICTOR	P49840	GSK3A	T1361	P1354L	1354	Missense	distal	-7	no	73.757	71.925	EPSD	COSMIC	72.838	Loss
CMGC_GSK_GSK3A_ST	Q6R327	RICTOR	P49840	GSK3A	T1361	F1360C	1360	Missense	proximal	-1	no	73.757	75.142	EPSD	COSMIC	72.838	Up-regulation
CMGC_GSK_GSK3A_ST	Q6R327	RICTOR	P49840	GSK3A	S1373	R1379K	1379	Missense	distal	6	no	83.132	82.813	EPSD	COSMIC	72.838	Down-regulation
CMGC_GSK_GSK3A_ST	Q6R327	RICTOR	P49840	GSK3A	S1373	E1372K	1372	Missense	proximal	-1	no	83.132	81.127	EPSD	COSMIC	72.838	Down-regulation
CMGC_GSK_GSK3A_ST	Q6R327	RICTOR	P49840	GSK3A	S1373	R1379S	1379	Missense	distal	6	no	83.132	81.726	EPSD	COSMIC	72.838	Down-regulation
CMGC_GSK_GSK3A_ST	Q6R327	RICTOR	P49840	GSK3A	S1373	F1380L	1380	Missense	distal	7	no	83.132	84.929	EPSD	COSMIC	72.838	Up-regulation
CMGC_GSK_GSK3A_ST	Q6R327	RICTOR	P49840	GSK3A	T1376	F1380L	1380	Missense	distal	4	no	70.684	87.565	EPSD	COSMIC	72.838	Gain
CMGC_GSK_GSK3A_ST	Q6R327	RICTOR	P49840	GSK3A	S1388	L1384S	1384	Missense	distal	-4	no	69.628	75.902	EPSD	COSMIC;GDSC;CCLE	72.838	Gain
CMGC_GSK_GSK3A_ST	Q6R327	RICTOR	P49840	GSK3A	S1407	R1410W	1410	Missense	distal	3	no	76.082	68.472	EPSD	COSMIC	72.838	Loss
CMGC_GSK_GSK3A_ST	Q6R327	RICTOR	P49840	GSK3A	S1407	S1406F	1406	Missense	proximal	-1	no	76.082	73.731	EPSD	COSMIC	72.838	Down-regulation
CMGC_GSK_GSK3A_ST	Q6R327	RICTOR	P49840	GSK3A	S1407	T1402P	1402	Missense	distal	-5	no	76.082	76.323	EPSD	COSMIC	72.838	Up-regulation
CMGC_GSK_GSK3A_ST	Q6R327	RICTOR	P49840	GSK3A	S1407	R1410Q	1410	Missense	distal	3	no	76.082	74.248	EPSD	COSMIC	72.838	Down-regulation
CMGC_GSK_GSK3A_ST	Q6R327	RICTOR	P49840	GSK3A	S1414	R1410W	1410	Missense	distal	-4	no	76.953	71.342	EPSD	COSMIC	72.838	Loss
CMGC_GSK_GSK3A_ST	Q6R327	RICTOR	P49840	GSK3A	S1414	G1420S	1420	Missense	distal	6	no	76.953	77.907	EPSD	COSMIC	72.838	Up-regulation
CMGC_GSK_GSK3A_ST	Q6R327	RICTOR	P49840	GSK3A	S1414	S1421L	1421	Missense	distal	7	no	76.953	76.331	EPSD	COSMIC	72.838	Down-regulation
CMGC_GSK_GSK3A_ST	Q6R327	RICTOR	P49840	GSK3A	S1414	R1410Q	1410	Missense	distal	-4	no	76.953	73.900	EPSD	COSMIC	72.838	Down-regulation
CMGC_GSK_GSK3A_ST	Q6R327	RICTOR	P49840	GSK3A	S1581	S1581F	1581	Missense	central	0	yes	74.501	0.000	EPSD	COSMIC	72.838	Loss
CMGC_GSK_GSK3A_ST	Q6R327	RICTOR	P49840	GSK3A	T1589	S1591N	1591	Missense	proximal	2	no	73.203	70.642	EPSD	COSMIC	72.838	Loss
CMGC_GSK_GSK3A_ST	Q6R327	RICTOR	P49840	GSK3A	T1695	T1695I	1695	Missense	central	0	yes	74.247	0.000	PhosphoSitePlus	COSMIC	72.838	Loss
CMGC_GSK_GSK3A_ST	Q6R327	RICTOR	P49840	GSK3A	T1695	T1695A	1695	Missense	central	0	yes	74.247	0.000	PhosphoSitePlus	COSMIC;CCLE	72.838	Loss
CMGC_GSK_GSK3A_ST	P01106	MYC	P49840	GSK3A	T58	P57S	57	Missense	proximal	-1	no	93.334	92.437	PhosphoSitePlus	COSMIC;CCLE	72.838	Down-regulation
CMGC_GSK_GSK3A_ST	P01106	MYC	P49840	GSK3A	T58	S62P	62	Missense	distal	4	no	93.334	87.348	PhosphoSitePlus	COSMIC;CCLE	72.838	Down-regulation
CMGC_GSK_GSK3A_ST	P01106	MYC	P49840	GSK3A	T58	P59L	59	Missense	proximal	1	no	93.334	79.282	PhosphoSitePlus	COSMIC;CCLE	72.838	Down-regulation
CMGC_GSK_GSK3A_ST	P01106	MYC	P49840	GSK3A	T58	T58N	58	Missense	central	0	yes	93.334	0.000	PhosphoSitePlus	COSMIC;CCLE	72.838	Loss
CMGC_GSK_GSK3A_ST	P01106	MYC	P49840	GSK3A	T58	P60H	60	Missense	proximal	2	no	93.334	92.012	PhosphoSitePlus	COSMIC;CCLE	72.838	Down-regulation
CMGC_GSK_GSK3A_ST	P01106	MYC	P49840	GSK3A	T58	P63L	63	Missense	distal	5	no	93.334	84.161	PhosphoSitePlus	COSMIC	72.838	Down-regulation
CMGC_GSK_GSK3A_ST	P01106	MYC	P49840	GSK3A	T58	P63H	63	Missense	distal	5	no	93.334	81.694	PhosphoSitePlus	COSMIC	72.838	Down-regulation
CMGC_GSK_GSK3A_ST	P01106	MYC	P49840	GSK3A	T58	T58A	58	Missense	central	0	yes	93.334	0.000	PhosphoSitePlus	COSMIC;CCLE	72.838	Loss
CMGC_GSK_GSK3A_ST	P01106	MYC	P49840	GSK3A	T58	P59A	59	Missense	proximal	1	no	93.334	79.667	PhosphoSitePlus	COSMIC;CCLE	72.838	Down-regulation
CMGC_GSK_GSK3A_ST	P01106	MYC	P49840	GSK3A	T58	P59R	59	Missense	proximal	1	no	93.334	84.681	PhosphoSitePlus	COSMIC	72.838	Down-regulation
CMGC_GSK_GSK3A_ST	P01106	MYC	P49840	GSK3A	T58	P60A	60	Missense	proximal	2	no	93.334	92.382	PhosphoSitePlus	COSMIC;CCLE	72.838	Down-regulation
CMGC_GSK_GSK3A_ST	P01106	MYC	P49840	GSK3A	T58	P57T	57	Missense	proximal	-1	no	93.334	94.119	PhosphoSitePlus	COSMIC;CCLE	72.838	Up-regulation
CMGC_GSK_GSK3A_ST	P01106	MYC	P49840	GSK3A	T58	P59S	59	Missense	proximal	1	no	93.334	77.642	PhosphoSitePlus	COSMIC;CCLE	72.838	Down-regulation
CMGC_GSK_GSK3A_ST	P01106	MYC	P49840	GSK3A	T58	S62F	62	Missense	distal	4	no	93.334	71.043	PhosphoSitePlus	COSMIC	72.838	Loss
CMGC_GSK_GSK3A_ST	P01106	MYC	P49840	GSK3A	T58	T58I	58	Missense	central	0	yes	93.334	0.000	PhosphoSitePlus	COSMIC;CCLE	72.838	Loss
CMGC_GSK_GSK3A_ST	P01106	MYC	P49840	GSK3A	T58	K51N	51	Missense	distal	-7	no	93.334	92.952	PhosphoSitePlus	COSMIC	72.838	Down-regulation
CMGC_GSK_GSK3A_ST	P01106	MYC	P49840	GSK3A	T58	T58P	58	Missense	central	0	yes	93.334	0.000	PhosphoSitePlus	COSMIC	72.838	Loss
CMGC_GSK_GSK3A_ST	P01106	MYC	P49840	GSK3A	T58	S64R	64	Missense	distal	6	no	93.334	94.740	PhosphoSitePlus	COSMIC;CCLE	72.838	Up-regulation
CMGC_GSK_GSK3A_ST	P01106	MYC	P49840	GSK3A	T58	P57L	57	Missense	proximal	-1	no	93.334	92.179	PhosphoSitePlus	COSMIC;CCLE	72.838	Down-regulation
CMGC_GSK_GSK3A_ST	P01106	MYC	P49840	GSK3A	T58	P63S	63	Missense	distal	5	no	93.334	87.777	PhosphoSitePlus	COSMIC;CCLE	72.838	Down-regulation
CMGC_GSK_GSK3A_ST	P01106	MYC	P49840	GSK3A	T58	P57F	57	Missense	proximal	-1	no	93.334	90.086	PhosphoSitePlus	COSMIC	72.838	Down-regulation
CMGC_GSK_GSK3A_ST	P01106	MYC	P49840	GSK3A	T58	P59Q	59	Missense	proximal	1	no	93.334	82.658	PhosphoSitePlus	COSMIC;CCLE	72.838	Down-regulation
CMGC_GSK_GSK3A_ST	P01106	MYC	P49840	GSK3A	T58	P59T	59	Missense	proximal	1	no	93.334	78.683	PhosphoSitePlus	COSMIC	72.838	Down-regulation
CMGC_GSK_GSK3A_ST	P01106	MYC	P49840	GSK3A	T58	P60S	60	Missense	proximal	2	no	93.334	92.645	PhosphoSitePlus	COSMIC	72.838	Down-regulation
CMGC_GSK_GSK3A_ST	P01106	MYC	P49840	GSK3A	T58	P63A	63	Missense	distal	5	no	93.334	86.858	PhosphoSitePlus	COSMIC	72.838	Down-regulation
CMGC_GSK_GSK3A_ST	P01106	MYC	P49840	GSK3A	T58	S64N	64	Missense	distal	6	no	93.334	94.688	PhosphoSitePlus	COSMIC	72.838	Up-regulation
CMGC_GSK_GSK3A_ST	P01106	MYC	P49840	GSK3A	T58	P60L	60	Missense	proximal	2	no	93.334	92.625	PhosphoSitePlus	COSMIC	72.838	Down-regulation
CMGC_GSK_GSK3A_ST	P01106	MYC	P49840	GSK3A	T58	P57A	57	Missense	proximal	-1	no	93.334	93.210	PhosphoSitePlus	COSMIC	72.838	Down-regulation
CMGC_GSK_GSK3A_ST	P01106	MYC	P49840	GSK3A	T58	L56V	56	Missense	proximal	-2	no	93.334	92.998	PhosphoSitePlus	COSMIC	72.838	Down-regulation
CMGC_GSK_GSK3A_ST	P01106	MYC	P49840	GSK3A	T58	P63R	63	Missense	distal	5	no	93.334	88.190	PhosphoSitePlus	COSMIC	72.838	Down-regulation
CMGC_GSK_GSK3A_ST	P01106	MYC	P49840	GSK3A	T58	L56M	56	Missense	proximal	-2	no	93.334	93.169	PhosphoSitePlus	COSMIC	72.838	Down-regulation
CMGC_GSK_GSK3A_ST	P01106	MYC	P49840	GSK3A	T58	P63T	63	Missense	distal	5	no	93.334	88.454	PhosphoSitePlus	COSMIC	72.838	Down-regulation
CMGC_GSK_GSK3A_ST	P01106	MYC	P49840	GSK3A	T58	S62A	62	Missense	distal	4	no	93.334	90.249	PhosphoSitePlus	COSMIC	72.838	Down-regulation
CMGC_GSK_GSK3A_ST	P01106	MYC	P49840	GSK3A	T58	P57R	57	Missense	proximal	-1	no	93.334	92.139	PhosphoSitePlus	COSMIC	72.838	Down-regulation
CMGC_GSK_GSK3A_ST	P01106	MYC	P49840	GSK3A	T58	P60T	60	Missense	proximal	2	no	93.334	94.057	PhosphoSitePlus	COSMIC;CCLE	72.838	Up-regulation
CMGC_GSK_GSK3A_ST	P01106	MYC	P49840	GSK3A	T58	E54V	54	Missense	distal	-4	no	93.334	89.227	PhosphoSitePlus	COSMIC	72.838	Down-regulation
CMGC_GSK_GSK3A_ST	P01106	MYC	P49840	GSK3A	T58	S64T	64	Missense	distal	6	no	93.334	94.065	PhosphoSitePlus	COSMIC	72.838	Up-regulation
CMGC_GSK_GSK3A_ST	P01106	MYC	P49840	GSK3A	T58	R65C	65	Missense	distal	7	no	93.334	93.057	PhosphoSitePlus	COSMIC	72.838	Down-regulation
CMGC_GSK_GSK3A_ST	P01106	MYC	P49840	GSK3A	T58	L55P	55	Missense	distal	-3	no	93.334	95.079	PhosphoSitePlus	COSMIC	72.838	Up-regulation
CMGC_GSK_GSK3A_ST	P01106	MYC	P49840	GSK3A	T58	L55M	55	Missense	distal	-3	no	93.334	94.523	PhosphoSitePlus	COSMIC	72.838	Up-regulation
CMGC_GSK_GSK3A_ST	P01106	MYC	P49840	GSK3A	T58	E54A	54	Missense	distal	-4	no	93.334	90.058	PhosphoSitePlus	COSMIC	72.838	Down-regulation
CMGC_GSK_GSK3A_ST	P01106	MYC	P49840	GSK3A	S62	P57S	57	Missense	distal	-5	no	79.709	79.795	EPSD	COSMIC;CCLE	72.838	Up-regulation
CMGC_GSK_GSK3A_ST	P01106	MYC	P49840	GSK3A	S62	S62P	62	Missense	central	0	yes	79.709	0.000	EPSD	COSMIC;CCLE	72.838	Loss
CMGC_GSK_GSK3A_ST	P01106	MYC	P49840	GSK3A	S62	P59L	59	Missense	distal	-3	no	79.709	77.964	EPSD	COSMIC;CCLE	72.838	Down-regulation
CMGC_GSK_GSK3A_ST	P01106	MYC	P49840	GSK3A	S62	T58N	58	Missense	distal	-4	no	79.709	76.327	EPSD	COSMIC;CCLE	72.838	Down-regulation
CMGC_GSK_GSK3A_ST	P01106	MYC	P49840	GSK3A	S62	P60H	60	Missense	proximal	-2	no	79.709	79.456	EPSD	COSMIC;CCLE	72.838	Down-regulation
CMGC_GSK_GSK3A_ST	P01106	MYC	P49840	GSK3A	S62	P63L	63	Missense	proximal	1	no	79.709	65.657	EPSD	COSMIC	72.838	Loss
CMGC_GSK_GSK3A_ST	P01106	MYC	P49840	GSK3A	S62	P63H	63	Missense	proximal	1	no	79.709	53.295	EPSD	COSMIC	72.838	Loss
CMGC_GSK_GSK3A_ST	P01106	MYC	P49840	GSK3A	S62	T58A	58	Missense	distal	-4	no	79.709	73.953	EPSD	COSMIC;CCLE	72.838	Down-regulation
CMGC_GSK_GSK3A_ST	P01106	MYC	P49840	GSK3A	S62	P59A	59	Missense	distal	-3	no	79.709	79.395	EPSD	COSMIC;CCLE	72.838	Down-regulation
CMGC_GSK_GSK3A_ST	P01106	MYC	P49840	GSK3A	S62	P59R	59	Missense	distal	-3	no	79.709	78.816	EPSD	COSMIC	72.838	Down-regulation
CMGC_GSK_GSK3A_ST	P01106	MYC	P49840	GSK3A	S62	P60A	60	Missense	proximal	-2	no	79.709	79.255	EPSD	COSMIC;CCLE	72.838	Down-regulation
CMGC_GSK_GSK3A_ST	P01106	MYC	P49840	GSK3A	S62	P57T	57	Missense	distal	-5	no	79.709	79.468	EPSD	COSMIC;CCLE	72.838	Down-regulation
CMGC_GSK_GSK3A_ST	P01106	MYC	P49840	GSK3A	S62	P59S	59	Missense	distal	-3	no	79.709	79.069	EPSD	COSMIC;CCLE	72.838	Down-regulation
CMGC_GSK_GSK3A_ST	P01106	MYC	P49840	GSK3A	S62	S62F	62	Missense	central	0	yes	79.709	0.000	EPSD	COSMIC	72.838	Loss
CMGC_GSK_GSK3A_ST	P01106	MYC	P49840	GSK3A	S62	T58I	58	Missense	distal	-4	no	79.709	73.115	EPSD	COSMIC;CCLE	72.838	Down-regulation
CMGC_GSK_GSK3A_ST	P01106	MYC	P49840	GSK3A	S62	T58P	58	Missense	distal	-4	no	79.709	75.313	EPSD	COSMIC	72.838	Down-regulation
CMGC_GSK_GSK3A_ST	P01106	MYC	P49840	GSK3A	S62	S64R	64	Missense	proximal	2	no	79.709	79.912	EPSD	COSMIC;CCLE	72.838	Up-regulation
CMGC_GSK_GSK3A_ST	P01106	MYC	P49840	GSK3A	S62	P57L	57	Missense	distal	-5	no	79.709	78.145	EPSD	COSMIC;CCLE	72.838	Down-regulation
CMGC_GSK_GSK3A_ST	P01106	MYC	P49840	GSK3A	S62	P63S	63	Missense	proximal	1	no	79.709	64.017	EPSD	COSMIC;CCLE	72.838	Loss
CMGC_GSK_GSK3A_ST	P01106	MYC	P49840	GSK3A	S62	R66H	66	Missense	distal	4	no	79.709	61.067	EPSD	COSMIC	72.838	Loss
CMGC_GSK_GSK3A_ST	P01106	MYC	P49840	GSK3A	S62	P57F	57	Missense	distal	-5	no	79.709	74.428	EPSD	COSMIC	72.838	Down-regulation
CMGC_GSK_GSK3A_ST	P01106	MYC	P49840	GSK3A	S62	P59Q	59	Missense	distal	-3	no	79.709	78.467	EPSD	COSMIC;CCLE	72.838	Down-regulation
CMGC_GSK_GSK3A_ST	P01106	MYC	P49840	GSK3A	S62	P59T	59	Missense	distal	-3	no	79.709	80.222	EPSD	COSMIC	72.838	Up-regulation
CMGC_GSK_GSK3A_ST	P01106	MYC	P49840	GSK3A	S62	P60S	60	Missense	proximal	-2	no	79.709	79.557	EPSD	COSMIC	72.838	Down-regulation
CMGC_GSK_GSK3A_ST	P01106	MYC	P49840	GSK3A	S62	P63A	63	Missense	proximal	1	no	79.709	66.042	EPSD	COSMIC	72.838	Loss
CMGC_GSK_GSK3A_ST	P01106	MYC	P49840	GSK3A	S62	S64N	64	Missense	proximal	2	no	79.709	77.147	EPSD	COSMIC	72.838	Down-regulation
CMGC_GSK_GSK3A_ST	P01106	MYC	P49840	GSK3A	S62	P60L	60	Missense	proximal	-2	no	79.709	78.842	EPSD	COSMIC	72.838	Down-regulation
CMGC_GSK_GSK3A_ST	P01106	MYC	P49840	GSK3A	S62	P57A	57	Missense	distal	-5	no	79.709	80.197	EPSD	COSMIC	72.838	Up-regulation
CMGC_GSK_GSK3A_ST	P01106	MYC	P49840	GSK3A	S62	L56V	56	Missense	distal	-6	no	79.709	80.562	EPSD	COSMIC	72.838	Up-regulation
CMGC_GSK_GSK3A_ST	P01106	MYC	P49840	GSK3A	S62	P63R	63	Missense	proximal	1	no	79.709	71.056	EPSD	COSMIC	72.838	Loss
CMGC_GSK_GSK3A_ST	P01106	MYC	P49840	GSK3A	S62	L56M	56	Missense	distal	-6	no	79.709	80.323	EPSD	COSMIC	72.838	Up-regulation
CMGC_GSK_GSK3A_ST	P01106	MYC	P49840	GSK3A	S62	L69V	69	Missense	distal	7	no	79.709	79.223	EPSD	COSMIC	72.838	Down-regulation
CMGC_GSK_GSK3A_ST	P01106	MYC	P49840	GSK3A	S62	P63T	63	Missense	proximal	1	no	79.709	65.057	EPSD	COSMIC	72.838	Loss
CMGC_GSK_GSK3A_ST	P01106	MYC	P49840	GSK3A	S62	S67F	67	Missense	distal	5	no	79.709	82.219	EPSD	COSMIC	72.838	Up-regulation
CMGC_GSK_GSK3A_ST	P01106	MYC	P49840	GSK3A	S62	S62A	62	Missense	central	0	yes	79.709	0.000	EPSD	COSMIC	72.838	Loss
CMGC_GSK_GSK3A_ST	P01106	MYC	P49840	GSK3A	S62	P57R	57	Missense	distal	-5	no	79.709	78.121	EPSD	COSMIC	72.838	Down-regulation
CMGC_GSK_GSK3A_ST	P01106	MYC	P49840	GSK3A	S62	L69P	69	Missense	distal	7	no	79.709	80.672	EPSD	COSMIC	72.838	Up-regulation
CMGC_GSK_GSK3A_ST	P01106	MYC	P49840	GSK3A	S62	P60T	60	Missense	proximal	-2	no	79.709	79.140	EPSD	COSMIC;CCLE	72.838	Down-regulation
CMGC_GSK_GSK3A_ST	P01106	MYC	P49840	GSK3A	S62	L69F	69	Missense	distal	7	no	79.709	77.911	EPSD	COSMIC	72.838	Down-regulation
CMGC_GSK_GSK3A_ST	P01106	MYC	P49840	GSK3A	S62	S64T	64	Missense	proximal	2	no	79.709	81.120	EPSD	COSMIC	72.838	Up-regulation
CMGC_GSK_GSK3A_ST	P01106	MYC	P49840	GSK3A	S62	R65C	65	Missense	distal	3	no	79.709	75.109	EPSD	COSMIC	72.838	Down-regulation
CMGC_GSK_GSK3A_ST	P01106	MYC	P49840	GSK3A	S62	L55P	55	Missense	distal	-7	no	79.709	81.540	EPSD	COSMIC	72.838	Up-regulation
CMGC_GSK_GSK3A_ST	P01106	MYC	P49840	GSK3A	S62	L55M	55	Missense	distal	-7	no	79.709	80.294	EPSD	COSMIC	72.838	Up-regulation
CMGC_GSK_GSK3A_ST	P01106	MYC	P49840	GSK3A	S67	S62P	62	Missense	distal	-5	no	91.781	91.695	EPSD	COSMIC;CCLE	72.838	Down-regulation
CMGC_GSK_GSK3A_ST	P01106	MYC	P49840	GSK3A	S67	P60H	60	Missense	distal	-7	no	91.781	92.787	EPSD	COSMIC;CCLE	72.838	Up-regulation
CMGC_GSK_GSK3A_ST	P01106	MYC	P49840	GSK3A	S67	P63L	63	Missense	distal	-4	no	91.781	89.093	EPSD	COSMIC	72.838	Down-regulation
CMGC_GSK_GSK3A_ST	P01106	MYC	P49840	GSK3A	S67	P63H	63	Missense	distal	-4	no	91.781	94.964	EPSD	COSMIC	72.838	Up-regulation
CMGC_GSK_GSK3A_ST	P01106	MYC	P49840	GSK3A	S67	P60A	60	Missense	distal	-7	no	91.781	92.584	EPSD	COSMIC;CCLE	72.838	Up-regulation
CMGC_GSK_GSK3A_ST	P01106	MYC	P49840	GSK3A	S67	S62F	62	Missense	distal	-5	no	91.781	86.414	EPSD	COSMIC	72.838	Down-regulation
CMGC_GSK_GSK3A_ST	P01106	MYC	P49840	GSK3A	S67	C70R	70	Missense	distal	3	no	91.781	96.381	EPSD	COSMIC	72.838	Up-regulation
CMGC_GSK_GSK3A_ST	P01106	MYC	P49840	GSK3A	S67	S64R	64	Missense	distal	-3	no	91.781	91.528	EPSD	COSMIC;CCLE	72.838	Down-regulation
CMGC_GSK_GSK3A_ST	P01106	MYC	P49840	GSK3A	S67	P63S	63	Missense	distal	-4	no	91.781	95.367	EPSD	COSMIC;CCLE	72.838	Up-regulation
CMGC_GSK_GSK3A_ST	P01106	MYC	P49840	GSK3A	S67	R66H	66	Missense	proximal	-1	no	91.781	92.230	EPSD	COSMIC	72.838	Up-regulation
CMGC_GSK_GSK3A_ST	P01106	MYC	P49840	GSK3A	S67	P60S	60	Missense	distal	-7	no	91.781	91.626	EPSD	COSMIC	72.838	Down-regulation
CMGC_GSK_GSK3A_ST	P01106	MYC	P49840	GSK3A	S67	S71L	71	Missense	distal	4	no	91.781	86.372	EPSD	COSMIC	72.838	Down-regulation
CMGC_GSK_GSK3A_ST	P01106	MYC	P49840	GSK3A	S67	P63A	63	Missense	distal	-4	no	91.781	90.421	EPSD	COSMIC	72.838	Down-regulation
CMGC_GSK_GSK3A_ST	P01106	MYC	P49840	GSK3A	S67	S64N	64	Missense	distal	-3	no	91.781	90.939	EPSD	COSMIC	72.838	Down-regulation
CMGC_GSK_GSK3A_ST	P01106	MYC	P49840	GSK3A	S67	P60L	60	Missense	distal	-7	no	91.781	89.950	EPSD	COSMIC	72.838	Down-regulation
CMGC_GSK_GSK3A_ST	P01106	MYC	P49840	GSK3A	S67	Y74N	74	Missense	distal	7	no	91.781	91.056	EPSD	COSMIC;CCLE	72.838	Down-regulation
CMGC_GSK_GSK3A_ST	P01106	MYC	P49840	GSK3A	S67	P63R	63	Missense	distal	-4	no	91.781	91.999	EPSD	COSMIC	72.838	Up-regulation
CMGC_GSK_GSK3A_ST	P01106	MYC	P49840	GSK3A	S67	L69V	69	Missense	proximal	2	no	91.781	90.720	EPSD	COSMIC	72.838	Down-regulation
CMGC_GSK_GSK3A_ST	P01106	MYC	P49840	GSK3A	S67	P63T	63	Missense	distal	-4	no	91.781	96.176	EPSD	COSMIC	72.838	Up-regulation
CMGC_GSK_GSK3A_ST	P01106	MYC	P49840	GSK3A	S67	Y74H	74	Missense	distal	7	no	91.781	91.643	EPSD	COSMIC	72.838	Down-regulation
CMGC_GSK_GSK3A_ST	P01106	MYC	P49840	GSK3A	S67	S67F	67	Missense	central	0	yes	91.781	0.000	EPSD	COSMIC	72.838	Loss
CMGC_GSK_GSK3A_ST	P01106	MYC	P49840	GSK3A	S67	S62A	62	Missense	distal	-5	no	91.781	92.182	EPSD	COSMIC	72.838	Up-regulation
CMGC_GSK_GSK3A_ST	P01106	MYC	P49840	GSK3A	S67	L69P	69	Missense	proximal	2	no	91.781	92.490	EPSD	COSMIC	72.838	Up-regulation
CMGC_GSK_GSK3A_ST	P01106	MYC	P49840	GSK3A	S67	C70W	70	Missense	distal	3	no	91.781	88.771	EPSD	COSMIC	72.838	Down-regulation
CMGC_GSK_GSK3A_ST	P01106	MYC	P49840	GSK3A	S67	P60T	60	Missense	distal	-7	no	91.781	92.474	EPSD	COSMIC;CCLE	72.838	Up-regulation
CMGC_GSK_GSK3A_ST	P01106	MYC	P49840	GSK3A	S67	S71W	71	Missense	distal	4	no	91.781	71.614	EPSD	COSMIC	72.838	Loss
CMGC_GSK_GSK3A_ST	P01106	MYC	P49840	GSK3A	S67	L69F	69	Missense	proximal	2	no	91.781	88.208	EPSD	COSMIC	72.838	Down-regulation
CMGC_GSK_GSK3A_ST	P01106	MYC	P49840	GSK3A	S67	S73P	73	Missense	distal	6	no	91.781	92.331	EPSD	COSMIC	72.838	Up-regulation
CMGC_GSK_GSK3A_ST	P01106	MYC	P49840	GSK3A	S67	S64T	64	Missense	distal	-3	no	91.781	92.933	EPSD	COSMIC	72.838	Up-regulation
CMGC_GSK_GSK3A_ST	P01106	MYC	P49840	GSK3A	S67	R65C	65	Missense	proximal	-2	no	91.781	90.277	EPSD	COSMIC	72.838	Down-regulation
CMGC_GSK_GSK3A_ST	P01106	MYC	P49840	GSK3A	S67	P72F	72	Missense	distal	5	no	91.781	88.734	EPSD	COSMIC	72.838	Down-regulation
CMGC_GSK_GSK3A_ST	P01106	MYC	P49840	GSK3A	S67	P72R	72	Missense	distal	5	no	91.781	86.637	EPSD	COSMIC	72.838	Down-regulation
CMGC_GSK_GSK3A_ST	P01106	MYC	P49840	GSK3A	S71	C70R	70	Missense	proximal	-1	no	88.696	89.364	EPSD	COSMIC	72.838	Up-regulation
CMGC_GSK_GSK3A_ST	P01106	MYC	P49840	GSK3A	S71	S64R	64	Missense	distal	-7	no	88.696	87.790	EPSD	COSMIC;CCLE	72.838	Down-regulation
CMGC_GSK_GSK3A_ST	P01106	MYC	P49840	GSK3A	S71	R66H	66	Missense	distal	-5	no	88.696	88.897	EPSD	COSMIC	72.838	Up-regulation
CMGC_GSK_GSK3A_ST	P01106	MYC	P49840	GSK3A	S71	A76V	76	Missense	distal	5	no	88.696	87.084	EPSD	COSMIC	72.838	Down-regulation
CMGC_GSK_GSK3A_ST	P01106	MYC	P49840	GSK3A	S71	V77I	77	Missense	distal	6	no	88.696	90.613	EPSD	COSMIC;CCLE	72.838	Up-regulation
CMGC_GSK_GSK3A_ST	P01106	MYC	P49840	GSK3A	S71	S71L	71	Missense	central	0	yes	88.696	0.000	EPSD	COSMIC	72.838	Loss
CMGC_GSK_GSK3A_ST	P01106	MYC	P49840	GSK3A	S71	S64N	64	Missense	distal	-7	no	88.696	88.980	EPSD	COSMIC	72.838	Up-regulation
CMGC_GSK_GSK3A_ST	P01106	MYC	P49840	GSK3A	S71	Y74N	74	Missense	distal	3	no	88.696	87.485	EPSD	COSMIC;CCLE	72.838	Down-regulation
CMGC_GSK_GSK3A_ST	P01106	MYC	P49840	GSK3A	S71	L69V	69	Missense	proximal	-2	no	88.696	88.360	EPSD	COSMIC	72.838	Down-regulation
CMGC_GSK_GSK3A_ST	P01106	MYC	P49840	GSK3A	S71	V77G	77	Missense	distal	6	no	88.696	91.356	EPSD	COSMIC	72.838	Up-regulation
CMGC_GSK_GSK3A_ST	P01106	MYC	P49840	GSK3A	S71	Y74H	74	Missense	distal	3	no	88.696	89.098	EPSD	COSMIC	72.838	Up-regulation
CMGC_GSK_GSK3A_ST	P01106	MYC	P49840	GSK3A	S71	S67F	67	Missense	distal	-4	no	88.696	80.938	EPSD	COSMIC	72.838	Down-regulation
CMGC_GSK_GSK3A_ST	P01106	MYC	P49840	GSK3A	S71	V75I	75	Missense	distal	4	no	88.696	90.202	EPSD	COSMIC	72.838	Up-regulation
CMGC_GSK_GSK3A_ST	P01106	MYC	P49840	GSK3A	S71	L69P	69	Missense	proximal	-2	no	88.696	89.564	EPSD	COSMIC	72.838	Up-regulation
CMGC_GSK_GSK3A_ST	P01106	MYC	P49840	GSK3A	S71	C70W	70	Missense	proximal	-1	no	88.696	89.426	EPSD	COSMIC	72.838	Up-regulation
CMGC_GSK_GSK3A_ST	P01106	MYC	P49840	GSK3A	S71	S71W	71	Missense	central	0	yes	88.696	0.000	EPSD	COSMIC	72.838	Loss
CMGC_GSK_GSK3A_ST	P01106	MYC	P49840	GSK3A	S71	L69F	69	Missense	proximal	-2	no	88.696	88.194	EPSD	COSMIC	72.838	Down-regulation
CMGC_GSK_GSK3A_ST	P01106	MYC	P49840	GSK3A	S71	S73P	73	Missense	proximal	2	no	88.696	89.385	EPSD	COSMIC	72.838	Up-regulation
CMGC_GSK_GSK3A_ST	P01106	MYC	P49840	GSK3A	S71	S64T	64	Missense	distal	-7	no	88.696	89.545	EPSD	COSMIC	72.838	Up-regulation
CMGC_GSK_GSK3A_ST	P01106	MYC	P49840	GSK3A	S71	R65C	65	Missense	distal	-6	no	88.696	88.904	EPSD	COSMIC	72.838	Up-regulation
CMGC_GSK_GSK3A_ST	P01106	MYC	P49840	GSK3A	S71	P72F	72	Missense	proximal	1	no	88.696	72.959	EPSD	COSMIC	72.838	Down-regulation
CMGC_GSK_GSK3A_ST	P01106	MYC	P49840	GSK3A	S71	P72R	72	Missense	proximal	1	no	88.696	80.044	EPSD	COSMIC	72.838	Down-regulation
CMGC_GSK_GSK3A_ST	P01106	MYC	P49840	GSK3A	T78	S81F	81	Missense	distal	3	no	75.225	71.858	EPSD	COSMIC;CCLE	72.838	Loss
CMGC_GSK_GSK3A_ST	P01106	MYC	P49840	GSK3A	T78	R83Q	83	Missense	distal	5	no	75.225	69.970	EPSD	COSMIC	72.838	Loss
CMGC_GSK_GSK3A_ST	P01106	MYC	P49840	GSK3A	T78	A76V	76	Missense	proximal	-2	no	75.225	74.476	EPSD	COSMIC	72.838	Down-regulation
CMGC_GSK_GSK3A_ST	P01106	MYC	P49840	GSK3A	T78	V77I	77	Missense	proximal	-1	no	75.225	73.777	EPSD	COSMIC;CCLE	72.838	Down-regulation
CMGC_GSK_GSK3A_ST	P01106	MYC	P49840	GSK3A	T78	S71L	71	Missense	distal	-7	no	75.225	73.549	EPSD	COSMIC	72.838	Down-regulation
CMGC_GSK_GSK3A_ST	P01106	MYC	P49840	GSK3A	T78	L82V	82	Missense	distal	4	no	75.225	75.055	EPSD	COSMIC	72.838	Down-regulation
CMGC_GSK_GSK3A_ST	P01106	MYC	P49840	GSK3A	T78	G84R	84	Missense	distal	6	no	75.225	77.584	EPSD	COSMIC	72.838	Up-regulation
CMGC_GSK_GSK3A_ST	P01106	MYC	P49840	GSK3A	T78	P79S	79	Missense	proximal	1	no	75.225	59.533	EPSD	COSMIC	72.838	Loss
CMGC_GSK_GSK3A_ST	P01106	MYC	P49840	GSK3A	T78	Y74N	74	Missense	distal	-4	no	75.225	73.533	EPSD	COSMIC;CCLE	72.838	Down-regulation
CMGC_GSK_GSK3A_ST	P01106	MYC	P49840	GSK3A	T78	F80L	80	Missense	proximal	2	no	75.225	78.798	EPSD	COSMIC	72.838	Up-regulation
CMGC_GSK_GSK3A_ST	P01106	MYC	P49840	GSK3A	T78	D85Y	85	Missense	distal	7	no	75.225	76.651	EPSD	COSMIC	72.838	Up-regulation
CMGC_GSK_GSK3A_ST	P01106	MYC	P49840	GSK3A	T78	V77G	77	Missense	proximal	-1	no	75.225	74.968	EPSD	COSMIC	72.838	Down-regulation
CMGC_GSK_GSK3A_ST	P01106	MYC	P49840	GSK3A	T78	S81C	81	Missense	distal	3	no	75.225	70.911	EPSD	COSMIC	72.838	Loss
CMGC_GSK_GSK3A_ST	P01106	MYC	P49840	GSK3A	T78	Y74H	74	Missense	distal	-4	no	75.225	75.702	EPSD	COSMIC	72.838	Up-regulation
CMGC_GSK_GSK3A_ST	P01106	MYC	P49840	GSK3A	T78	D85E	85	Missense	distal	7	no	75.225	77.054	EPSD	COSMIC	72.838	Up-regulation
CMGC_GSK_GSK3A_ST	P01106	MYC	P49840	GSK3A	T78	V75I	75	Missense	distal	-3	no	75.225	72.877	EPSD	COSMIC	72.838	Down-regulation
CMGC_GSK_GSK3A_ST	P01106	MYC	P49840	GSK3A	T78	S71W	71	Missense	distal	-7	no	75.225	72.937	EPSD	COSMIC	72.838	Down-regulation
CMGC_GSK_GSK3A_ST	P01106	MYC	P49840	GSK3A	T78	L82H	82	Missense	distal	4	no	75.225	52.597	EPSD	COSMIC	72.838	Loss
CMGC_GSK_GSK3A_ST	P01106	MYC	P49840	GSK3A	T78	S73P	73	Missense	distal	-5	no	75.225	75.139	EPSD	COSMIC	72.838	Down-regulation
CMGC_GSK_GSK3A_ST	P01106	MYC	P49840	GSK3A	T78	P72F	72	Missense	distal	-6	no	75.225	76.802	EPSD	COSMIC	72.838	Up-regulation
CMGC_GSK_GSK3A_ST	P01106	MYC	P49840	GSK3A	T78	P72R	72	Missense	distal	-6	no	75.225	75.559	EPSD	COSMIC	72.838	Up-regulation
CMGC_GSK_GSK3A_ST	P01106	MYC	P49840	GSK3A	S151	K157T	157	Missense	distal	6	no	82.900	82.545	EPSD	COSMIC	72.838	Down-regulation
CMGC_GSK_GSK3A_ST	P01106	MYC	P49840	GSK3A	S151	A155S	155	Missense	distal	4	no	82.900	85.986	EPSD	COSMIC	72.838	Up-regulation
CMGC_GSK_GSK3A_ST	P01106	MYC	P49840	GSK3A	S151	K157N	157	Missense	distal	6	no	82.900	83.168	EPSD	COSMIC	72.838	Up-regulation
CMGC_GSK_GSK3A_ST	P01106	MYC	P49840	GSK3A	S151	A155T	155	Missense	distal	4	no	82.900	85.486	EPSD	COSMIC	72.838	Up-regulation
CMGC_GSK_GSK3A_ST	P01106	MYC	P49840	GSK3A	S151	Y152N	152	Missense	proximal	1	no	82.900	24.375	EPSD	COSMIC	72.838	Loss
CMGC_GSK_GSK3A_ST	P01106	MYC	P49840	GSK3A	S151	A150D	150	Missense	proximal	-1	no	82.900	81.485	EPSD	COSMIC	72.838	Down-regulation
CMGC_GSK_GSK3A_ST	P01106	MYC	P49840	GSK3A	S151	V145L	145	Missense	distal	-6	no	82.900	82.048	EPSD	COSMIC	72.838	Down-regulation
CMGC_GSK_GSK3A_ST	P01106	MYC	P49840	GSK3A	S151	S146L	146	Missense	distal	-5	no	82.900	81.251	EPSD	COSMIC	72.838	Down-regulation
CMGC_GSK_GSK3A_ST	P01106	MYC	P49840	GSK3A	S151	L149V	149	Missense	proximal	-2	no	82.900	82.564	EPSD	COSMIC;CCLE	72.838	Down-regulation
CMGC_GSK_GSK3A_ST	P01106	MYC	P49840	GSK3A	S151	A154T	154	Missense	distal	3	no	82.900	84.281	EPSD	COSMIC	72.838	Up-regulation
CMGC_GSK_GSK3A_ST	P01106	MYC	P49840	GSK3A	S151	A150S	150	Missense	proximal	-1	no	82.900	82.127	EPSD	COSMIC	72.838	Down-regulation
CMGC_GSK_GSK3A_ST	P01106	MYC	P49840	GSK3A	S151	D158G	158	Missense	distal	7	no	82.900	84.337	EPSD	COSMIC	72.838	Up-regulation
CMGC_GSK_GSK3A_ST	P01106	MYC	P49840	GSK3A	S151	L144V	144	Missense	distal	-7	no	82.900	84.661	EPSD	COSMIC	72.838	Up-regulation
CMGC_GSK_GSK3A_ST	P01106	MYC	P49840	GSK3A	S151	L144Y	144	Missense	distal	-7	no	82.900	85.321	EPSD	COSMIC	72.838	Up-regulation
CMGC_GSK_GSK3A_ST	P01106	MYC	P49840	GSK3A	S151	R156G	156	Missense	distal	5	no	82.900	82.454	EPSD	COSMIC	72.838	Down-regulation
CMGC_GSK_GSK3A_ST	P01106	MYC	P49840	GSK3A	S151	A154G	154	Missense	distal	3	no	82.900	81.651	EPSD	COSMIC	72.838	Down-regulation
CMGC_GSK_GSK3A_ST	P01106	MYC	P49840	GSK3A	S151	Q153H	153	Missense	proximal	2	no	82.900	82.662	EPSD	COSMIC	72.838	Down-regulation
CMGC_GSK_GSK3A_ST	P01106	MYC	P49840	GSK3A	S159	K157T	157	Missense	proximal	-2	no	72.973	71.679	EPSD	COSMIC	72.838	Loss
CMGC_GSK_GSK3A_ST	P01106	MYC	P49840	GSK3A	S159	A155S	155	Missense	distal	-4	no	72.973	77.919	EPSD	COSMIC	72.838	Up-regulation
CMGC_GSK_GSK3A_ST	P01106	MYC	P49840	GSK3A	S159	K157N	157	Missense	proximal	-2	no	72.973	71.210	EPSD	COSMIC	72.838	Loss
CMGC_GSK_GSK3A_ST	P01106	MYC	P49840	GSK3A	S159	A155T	155	Missense	distal	-4	no	72.973	78.728	EPSD	COSMIC	72.838	Up-regulation
CMGC_GSK_GSK3A_ST	P01106	MYC	P49840	GSK3A	S159	Y152N	152	Missense	distal	-7	no	72.973	72.512	EPSD	COSMIC	72.838	Loss
CMGC_GSK_GSK3A_ST	P01106	MYC	P49840	GSK3A	S159	N163K	163	Missense	distal	4	no	72.973	76.746	EPSD	COSMIC	72.838	Up-regulation
CMGC_GSK_GSK3A_ST	P01106	MYC	P49840	GSK3A	S159	P162R	162	Missense	distal	3	no	72.973	71.926	EPSD	COSMIC	72.838	Loss
CMGC_GSK_GSK3A_ST	P01106	MYC	P49840	GSK3A	S159	A154T	154	Missense	distal	-5	no	72.973	72.244	EPSD	COSMIC	72.838	Loss
CMGC_GSK_GSK3A_ST	P01106	MYC	P49840	GSK3A	S159	G160D	160	Missense	proximal	1	no	72.973	62.803	EPSD	COSMIC	72.838	Loss
CMGC_GSK_GSK3A_ST	P01106	MYC	P49840	GSK3A	S159	S159N	159	Missense	central	0	yes	72.973	0.000	EPSD	COSMIC	72.838	Loss
CMGC_GSK_GSK3A_ST	P01106	MYC	P49840	GSK3A	S159	A165S	165	Missense	distal	6	no	72.973	74.968	EPSD	COSMIC	72.838	Up-regulation
CMGC_GSK_GSK3A_ST	P01106	MYC	P49840	GSK3A	S159	A165T	165	Missense	distal	6	no	72.973	75.699	EPSD	COSMIC	72.838	Up-regulation
CMGC_GSK_GSK3A_ST	P01106	MYC	P49840	GSK3A	S159	D158G	158	Missense	proximal	-1	no	72.973	73.590	EPSD	COSMIC	72.838	Up-regulation
CMGC_GSK_GSK3A_ST	P01106	MYC	P49840	GSK3A	S159	R166H	166	Missense	distal	7	no	72.973	73.445	EPSD	COSMIC	72.838	Up-regulation
CMGC_GSK_GSK3A_ST	P01106	MYC	P49840	GSK3A	S159	S161N	161	Missense	proximal	2	no	72.973	70.411	EPSD	COSMIC	72.838	Loss
CMGC_GSK_GSK3A_ST	P01106	MYC	P49840	GSK3A	S159	S161T	161	Missense	proximal	2	no	72.973	74.384	EPSD	COSMIC	72.838	Up-regulation
CMGC_GSK_GSK3A_ST	P01106	MYC	P49840	GSK3A	S159	R156G	156	Missense	distal	-3	no	72.973	72.807	EPSD	COSMIC	72.838	Loss
CMGC_GSK_GSK3A_ST	P01106	MYC	P49840	GSK3A	S159	A154G	154	Missense	distal	-5	no	72.973	72.387	EPSD	COSMIC	72.838	Loss
CMGC_GSK_GSK3A_ST	P01106	MYC	P49840	GSK3A	S159	S159R	159	Missense	central	0	yes	72.973	0.000	EPSD	COSMIC	72.838	Loss
CMGC_GSK_GSK3A_ST	P01106	MYC	P49840	GSK3A	S159	Q153H	153	Missense	distal	-6	no	72.973	73.090	EPSD	COSMIC	72.838	Up-regulation
CMGC_GSK_GSK3A_ST	P01106	MYC	P49840	GSK3A	S159	A165D	165	Missense	distal	6	no	72.973	74.730	EPSD	COSMIC	72.838	Up-regulation
CMGC_GSK_GSK3A_ST	P01106	MYC	P49840	GSK3A	S161	K157T	157	Missense	distal	-4	no	75.825	80.098	EPSD	COSMIC	72.838	Up-regulation
CMGC_GSK_GSK3A_ST	P01106	MYC	P49840	GSK3A	S161	A155S	155	Missense	distal	-6	no	75.825	75.115	EPSD	COSMIC	72.838	Down-regulation
CMGC_GSK_GSK3A_ST	P01106	MYC	P49840	GSK3A	S161	K157N	157	Missense	distal	-4	no	75.825	76.716	EPSD	COSMIC	72.838	Up-regulation
CMGC_GSK_GSK3A_ST	P01106	MYC	P49840	GSK3A	S161	A155T	155	Missense	distal	-6	no	75.825	75.243	EPSD	COSMIC	72.838	Down-regulation
CMGC_GSK_GSK3A_ST	P01106	MYC	P49840	GSK3A	S161	N163K	163	Missense	proximal	2	no	75.825	79.911	EPSD	COSMIC	72.838	Up-regulation
CMGC_GSK_GSK3A_ST	P01106	MYC	P49840	GSK3A	S161	P162R	162	Missense	proximal	1	no	75.825	67.172	EPSD	COSMIC	72.838	Loss
CMGC_GSK_GSK3A_ST	P01106	MYC	P49840	GSK3A	S161	A154T	154	Missense	distal	-7	no	75.825	75.715	EPSD	COSMIC	72.838	Down-regulation
CMGC_GSK_GSK3A_ST	P01106	MYC	P49840	GSK3A	S161	G160D	160	Missense	proximal	-1	no	75.825	75.208	EPSD	COSMIC	72.838	Down-regulation
CMGC_GSK_GSK3A_ST	P01106	MYC	P49840	GSK3A	S161	S159N	159	Missense	proximal	-2	no	75.825	74.939	EPSD	COSMIC	72.838	Down-regulation
CMGC_GSK_GSK3A_ST	P01106	MYC	P49840	GSK3A	S161	A165S	165	Missense	distal	4	no	75.825	78.910	EPSD	COSMIC	72.838	Up-regulation
CMGC_GSK_GSK3A_ST	P01106	MYC	P49840	GSK3A	S161	A165T	165	Missense	distal	4	no	75.825	78.410	EPSD	COSMIC	72.838	Up-regulation
CMGC_GSK_GSK3A_ST	P01106	MYC	P49840	GSK3A	S161	S159T	159	Missense	proximal	-2	no	75.825	75.408	EPSD	COSMIC	72.838	Down-regulation
CMGC_GSK_GSK3A_ST	P01106	MYC	P49840	GSK3A	S161	D158G	158	Missense	distal	-3	no	75.825	76.035	EPSD	COSMIC	72.838	Up-regulation
CMGC_GSK_GSK3A_ST	P01106	MYC	P49840	GSK3A	S161	R166H	166	Missense	distal	5	no	75.825	69.330	EPSD	COSMIC	72.838	Loss
CMGC_GSK_GSK3A_ST	P01106	MYC	P49840	GSK3A	S161	S161N	161	Missense	central	0	yes	75.825	0.000	EPSD	COSMIC	72.838	Loss
CMGC_GSK_GSK3A_ST	P01106	MYC	P49840	GSK3A	S161	R156G	156	Missense	distal	-5	no	75.825	77.314	EPSD	COSMIC	72.838	Up-regulation
CMGC_GSK_GSK3A_ST	P01106	MYC	P49840	GSK3A	S161	A154G	154	Missense	distal	-7	no	75.825	75.060	EPSD	COSMIC	72.838	Down-regulation
CMGC_GSK_GSK3A_ST	P01106	MYC	P49840	GSK3A	S161	S159R	159	Missense	proximal	-2	no	75.825	76.188	EPSD	COSMIC	72.838	Up-regulation
CMGC_GSK_GSK3A_ST	P01106	MYC	P49840	GSK3A	S161	A165D	165	Missense	distal	4	no	75.825	74.568	EPSD	COSMIC	72.838	Down-regulation
CMGC_GSK_GSK3A_ST	P01106	MYC	P49840	GSK3A	S172	S175N	175	Missense	distal	3	no	81.732	84.416	EPSD	COSMIC	72.838	Up-regulation
CMGC_GSK_GSK3A_ST	P01106	MYC	P49840	GSK3A	S172	S175T	175	Missense	distal	3	no	81.732	83.755	EPSD	COSMIC;CCLE	72.838	Up-regulation
CMGC_GSK_GSK3A_ST	P01106	MYC	P49840	GSK3A	S172	L176F	176	Missense	distal	4	no	81.732	64.851	EPSD	COSMIC	72.838	Loss
CMGC_GSK_GSK3A_ST	P01106	MYC	P49840	GSK3A	S172	C171S	171	Missense	proximal	-1	no	81.732	82.698	EPSD	COSMIC	72.838	Up-regulation
CMGC_GSK_GSK3A_ST	P01106	MYC	P49840	GSK3A	S172	A165S	165	Missense	distal	-7	no	81.732	80.774	EPSD	COSMIC	72.838	Down-regulation
CMGC_GSK_GSK3A_ST	P01106	MYC	P49840	GSK3A	S172	S172C	172	Missense	central	0	yes	81.732	0.000	EPSD	COSMIC	72.838	Loss
CMGC_GSK_GSK3A_ST	P01106	MYC	P49840	GSK3A	S172	A165T	165	Missense	distal	-7	no	81.732	81.622	EPSD	COSMIC	72.838	Down-regulation
CMGC_GSK_GSK3A_ST	P01106	MYC	P49840	GSK3A	S172	S175R	175	Missense	distal	3	no	81.732	82.018	EPSD	COSMIC	72.838	Up-regulation
CMGC_GSK_GSK3A_ST	P01106	MYC	P49840	GSK3A	S172	R166H	166	Missense	distal	-6	no	81.732	81.508	EPSD	COSMIC	72.838	Down-regulation
CMGC_GSK_GSK3A_ST	P01106	MYC	P49840	GSK3A	S172	V170I	170	Missense	proximal	-2	no	81.732	81.900	EPSD	COSMIC	72.838	Up-regulation
CMGC_GSK_GSK3A_ST	P01106	MYC	P49840	GSK3A	S172	S174T	174	Missense	proximal	2	no	81.732	83.144	EPSD	COSMIC;CCLE	72.838	Up-regulation
CMGC_GSK_GSK3A_ST	P01106	MYC	P49840	GSK3A	S172	L178V	178	Missense	distal	6	no	81.732	80.449	EPSD	COSMIC;CCLE	72.838	Down-regulation
CMGC_GSK_GSK3A_ST	P01106	MYC	P49840	GSK3A	S172	Q179H	179	Missense	distal	7	no	81.732	81.701	EPSD	COSMIC;CCLE	72.838	Down-regulation
CMGC_GSK_GSK3A_ST	P01106	MYC	P49840	GSK3A	S172	T173S	173	Missense	proximal	1	no	81.732	80.691	EPSD	COSMIC	72.838	Down-regulation
CMGC_GSK_GSK3A_ST	P01106	MYC	P49840	GSK3A	S172	S169C	169	Missense	distal	-3	no	81.732	80.845	EPSD	COSMIC	72.838	Down-regulation
CMGC_GSK_GSK3A_ST	P01106	MYC	P49840	GSK3A	S172	C171Y	171	Missense	proximal	-1	no	81.732	84.018	EPSD	COSMIC	72.838	Up-regulation
CMGC_GSK_GSK3A_ST	P01106	MYC	P49840	GSK3A	S172	L176M	176	Missense	distal	4	no	81.732	83.985	EPSD	COSMIC	72.838	Up-regulation
CMGC_GSK_GSK3A_ST	P01106	MYC	P49840	GSK3A	S172	S169N	169	Missense	distal	-3	no	81.732	80.890	EPSD	COSMIC	72.838	Down-regulation
CMGC_GSK_GSK3A_ST	P01106	MYC	P49840	GSK3A	S172	S174Y	174	Missense	proximal	2	no	81.732	81.613	EPSD	COSMIC	72.838	Down-regulation
CMGC_GSK_GSK3A_ST	P01106	MYC	P49840	GSK3A	S172	S169R	169	Missense	distal	-3	no	81.732	81.479	EPSD	COSMIC	72.838	Down-regulation
CMGC_GSK_GSK3A_ST	P01106	MYC	P49840	GSK3A	S172	A165D	165	Missense	distal	-7	no	81.732	79.357	EPSD	COSMIC	72.838	Down-regulation
CMGC_GSK_GSK3A_ST	P01106	MYC	P49840	GSK3A	S172	S174N	174	Missense	proximal	2	no	81.732	79.171	EPSD	COSMIC	72.838	Down-regulation
CMGC_GSK_GSK3A_ST	P01106	MYC	P49840	GSK3A	S172	S174R	174	Missense	proximal	2	no	81.732	81.936	EPSD	COSMIC	72.838	Up-regulation
CMGC_GSK_GSK3A_ST	P01106	MYC	P49840	GSK3A	S172	Q179K	179	Missense	distal	7	no	81.732	82.387	EPSD	COSMIC	72.838	Up-regulation
CMGC_GSK_GSK3A_ST	P01106	MYC	P49840	GSK3A	S172	L176V	176	Missense	distal	4	no	81.732	81.562	EPSD	COSMIC	72.838	Down-regulation
CMGC_GSK_GSK3A_ST	P01106	MYC	P49840	GSK3A	S249	P245S	245	Missense	distal	-4	no	75.277	78.863	EPSD	COSMIC	72.838	Up-regulation
CMGC_GSK_GSK3A_ST	P01106	MYC	P49840	GSK3A	S249	E242Q	242	Missense	distal	-7	no	75.277	74.507	EPSD	COSMIC	72.838	Down-regulation
CMGC_GSK_GSK3A_ST	P01106	MYC	P49840	GSK3A	S249	E242V	242	Missense	distal	-7	no	75.277	75.285	EPSD	COSMIC	72.838	Up-regulation
CMGC_GSK_GSK3A_ST	P01106	MYC	P49840	GSK3A	S249	E253K	253	Missense	distal	4	no	75.277	76.621	EPSD	COSMIC	72.838	Up-regulation
CMGC_GSK_GSK3A_ST	P01106	MYC	P49840	GSK3A	S249	S249I	249	Missense	central	0	yes	75.277	0.000	EPSD	COSMIC	72.838	Loss
CMGC_GSK_GSK3A_ST	P01106	MYC	P49840	GSK3A	S249	D251N	251	Missense	proximal	2	no	75.277	76.012	EPSD	COSMIC;CCLE	72.838	Up-regulation
CMGC_GSK_GSK3A_ST	P01106	MYC	P49840	GSK3A	S249	P245A	245	Missense	distal	-4	no	75.277	73.917	EPSD	COSMIC	72.838	Down-regulation
CMGC_GSK_GSK3A_ST	P01106	MYC	P49840	GSK3A	S249	S252F	252	Missense	distal	3	no	75.277	71.909	EPSD	COSMIC	72.838	Loss
CMGC_GSK_GSK3A_ST	P01106	MYC	P49840	GSK3A	S249	S249N	249	Missense	central	0	yes	75.277	0.000	EPSD	COSMIC;CCLE	72.838	Loss
CMGC_GSK_GSK3A_ST	P01106	MYC	P49840	GSK3A	S249	T244K	244	Missense	distal	-5	no	75.277	74.700	EPSD	COSMIC	72.838	Down-regulation
CMGC_GSK_GSK3A_ST	P01106	MYC	P49840	GSK3A	S249	P245Q	245	Missense	distal	-4	no	75.277	72.442	EPSD	COSMIC	72.838	Loss
CMGC_GSK_GSK3A_ST	P01106	MYC	P49840	GSK3A	S249	P246S	246	Missense	distal	-3	no	75.277	74.637	EPSD	COSMIC	72.838	Down-regulation
CMGC_GSK_GSK3A_ST	P01106	MYC	P49840	GSK3A	S249	S250I	250	Missense	proximal	1	no	75.277	70.547	EPSD	COSMIC	72.838	Loss
CMGC_GSK_GSK3A_ST	P01106	MYC	P49840	GSK3A	S249	S250C	250	Missense	proximal	1	no	75.277	63.927	EPSD	COSMIC	72.838	Loss
CMGC_GSK_GSK3A_ST	P01106	MYC	P49840	GSK3A	S249	P246R	246	Missense	distal	-3	no	75.277	74.384	EPSD	COSMIC	72.838	Down-regulation
CMGC_GSK_GSK3A_ST	P01106	MYC	P49840	GSK3A	S249	E243G	243	Missense	distal	-6	no	75.277	75.890	EPSD	COSMIC	72.838	Up-regulation
CMGC_GSK_GSK3A_ST	P01106	MYC	P49840	GSK3A	S249	D251E	251	Missense	proximal	2	no	75.277	79.177	EPSD	COSMIC	72.838	Up-regulation
CMGC_GSK_GSK3A_ST	P01106	MYC	P49840	GSK3A	S249	P245L	245	Missense	distal	-4	no	75.277	72.589	EPSD	COSMIC	72.838	Loss
CMGC_GSK_GSK3A_ST	P01106	MYC	P49840	GSK3A	S249	S250R	250	Missense	proximal	1	no	75.277	82.316	EPSD	COSMIC	72.838	Up-regulation
CMGC_GSK_GSK3A_ST	P01106	MYC	P49840	GSK3A	S249	S252Y	252	Missense	distal	3	no	75.277	79.172	EPSD	COSMIC	72.838	Up-regulation
CMGC_GSK_GSK3A_ST	P01106	MYC	P49840	GSK3A	S249	T247I	247	Missense	proximal	-2	no	75.277	74.810	EPSD	COSMIC	72.838	Down-regulation
CMGC_GSK_GSK3A_ST	P01106	MYC	P49840	GSK3A	S249	E243Q	243	Missense	distal	-6	no	75.277	75.706	EPSD	COSMIC	72.838	Up-regulation
CMGC_GSK_GSK3A_ST	P01106	MYC	P49840	GSK3A	S249	S249R	249	Missense	central	0	yes	75.277	0.000	EPSD	COSMIC;CCLE	72.838	Loss
CMGC_GSK_GSK3A_ST	P01106	MYC	P49840	GSK3A	S249	E243V	243	Missense	distal	-6	no	75.277	76.693	EPSD	COSMIC	72.838	Up-regulation
CMGC_GSK_GSK3A_ST	P01106	MYC	P49840	GSK3A	S277	S283F	283	Missense	distal	6	no	77.317	72.760	EPSD	COSMIC	72.838	Loss
CMGC_GSK_GSK3A_ST	P01106	MYC	P49840	GSK3A	S277	S277L	277	Missense	central	0	yes	77.317	0.000	EPSD	COSMIC	72.838	Loss
CMGC_GSK_GSK3A_ST	P01106	MYC	P49840	GSK3A	S277	S279C	279	Missense	proximal	2	no	77.317	74.571	EPSD	COSMIC	72.838	Down-regulation
CMGC_GSK_GSK3A_ST	P01106	MYC	P49840	GSK3A	S277	S283Y	283	Missense	distal	6	no	77.317	77.988	EPSD	COSMIC	72.838	Up-regulation
CMGC_GSK_GSK3A_ST	P01106	MYC	P49840	GSK3A	S277	P273H	273	Missense	distal	-4	no	77.317	80.500	EPSD	COSMIC	72.838	Up-regulation
CMGC_GSK_GSK3A_ST	P01106	MYC	P49840	GSK3A	S277	P282A	282	Missense	distal	5	no	77.317	70.841	EPSD	COSMIC	72.838	Loss
CMGC_GSK_GSK3A_ST	P01106	MYC	P49840	GSK3A	S277	G280R	280	Missense	distal	3	no	77.317	78.210	EPSD	COSMIC	72.838	Up-regulation
CMGC_GSK_GSK3A_ST	P01106	MYC	P49840	GSK3A	S277	G274D	274	Missense	distal	-3	no	77.317	77.107	EPSD	COSMIC	72.838	Down-regulation
CMGC_GSK_GSK3A_ST	P01106	MYC	P49840	GSK3A	S277	A272P	272	Missense	distal	-5	no	77.317	76.829	EPSD	COSMIC	72.838	Down-regulation
CMGC_GSK_GSK3A_ST	P01106	MYC	P49840	GSK3A	S277	S281F	281	Missense	distal	4	no	77.317	55.026	EPSD	COSMIC	72.838	Loss
CMGC_GSK_GSK3A_ST	P01106	MYC	P49840	GSK3A	S279	S283F	283	Missense	distal	4	no	86.015	63.725	EPSD	COSMIC	72.838	Loss
CMGC_GSK_GSK3A_ST	P01106	MYC	P49840	GSK3A	S279	S277L	277	Missense	proximal	-2	no	86.015	85.300	EPSD	COSMIC	72.838	Down-regulation
CMGC_GSK_GSK3A_ST	P01106	MYC	P49840	GSK3A	S279	S279C	279	Missense	central	0	yes	86.015	0.000	EPSD	COSMIC	72.838	Loss
CMGC_GSK_GSK3A_ST	P01106	MYC	P49840	GSK3A	S279	S283Y	283	Missense	distal	4	no	86.015	80.392	EPSD	COSMIC	72.838	Down-regulation
CMGC_GSK_GSK3A_ST	P01106	MYC	P49840	GSK3A	S279	P273H	273	Missense	distal	-6	no	86.015	86.124	EPSD	COSMIC	72.838	Up-regulation
CMGC_GSK_GSK3A_ST	P01106	MYC	P49840	GSK3A	S279	P282A	282	Missense	distal	3	no	86.015	85.325	EPSD	COSMIC	72.838	Down-regulation
CMGC_GSK_GSK3A_ST	P01106	MYC	P49840	GSK3A	S279	G285E	285	Missense	distal	6	no	86.015	87.510	EPSD	COSMIC	72.838	Up-regulation
CMGC_GSK_GSK3A_ST	P01106	MYC	P49840	GSK3A	S279	G280R	280	Missense	proximal	1	no	86.015	87.838	EPSD	COSMIC	72.838	Up-regulation
CMGC_GSK_GSK3A_ST	P01106	MYC	P49840	GSK3A	S279	G274D	274	Missense	distal	-5	no	86.015	83.093	EPSD	COSMIC	72.838	Down-regulation
CMGC_GSK_GSK3A_ST	P01106	MYC	P49840	GSK3A	S279	A272P	272	Missense	distal	-7	no	86.015	85.212	EPSD	COSMIC	72.838	Down-regulation
CMGC_GSK_GSK3A_ST	P01106	MYC	P49840	GSK3A	S279	S281F	281	Missense	proximal	2	no	86.015	82.422	EPSD	COSMIC	72.838	Down-regulation
CMGC_GSK_GSK3A_ST	P01106	MYC	P49840	GSK3A	S281	S283F	283	Missense	proximal	2	no	75.903	72.310	EPSD	COSMIC	72.838	Loss
CMGC_GSK_GSK3A_ST	P01106	MYC	P49840	GSK3A	S281	S277L	277	Missense	distal	-4	no	75.903	69.629	EPSD	COSMIC	72.838	Loss
CMGC_GSK_GSK3A_ST	P01106	MYC	P49840	GSK3A	S281	H287Q	287	Missense	distal	6	no	75.903	75.477	EPSD	COSMIC	72.838	Down-regulation
CMGC_GSK_GSK3A_ST	P01106	MYC	P49840	GSK3A	S281	S279C	279	Missense	proximal	-2	no	75.903	74.762	EPSD	COSMIC	72.838	Down-regulation
CMGC_GSK_GSK3A_ST	P01106	MYC	P49840	GSK3A	S281	S283Y	283	Missense	proximal	2	no	75.903	75.784	EPSD	COSMIC	72.838	Down-regulation
CMGC_GSK_GSK3A_ST	P01106	MYC	P49840	GSK3A	S281	P282A	282	Missense	proximal	1	no	75.903	62.236	EPSD	COSMIC	72.838	Loss
CMGC_GSK_GSK3A_ST	P01106	MYC	P49840	GSK3A	S281	G285E	285	Missense	distal	4	no	75.903	89.482	EPSD	COSMIC	72.838	Up-regulation
CMGC_GSK_GSK3A_ST	P01106	MYC	P49840	GSK3A	S281	G280R	280	Missense	proximal	-1	no	75.903	75.629	EPSD	COSMIC	72.838	Down-regulation
CMGC_GSK_GSK3A_ST	P01106	MYC	P49840	GSK3A	S281	G274D	274	Missense	distal	-7	no	75.903	74.292	EPSD	COSMIC	72.838	Down-regulation
CMGC_GSK_GSK3A_ST	P01106	MYC	P49840	GSK3A	S281	S281F	281	Missense	central	0	yes	75.903	0.000	EPSD	COSMIC	72.838	Loss
CMGC_GSK_GSK3A_ST	P01106	MYC	P49840	GSK3A	S293	S293C	293	Missense	central	0	yes	95.404	0.000	EPSD	COSMIC	72.838	Loss
CMGC_GSK_GSK3A_ST	P01106	MYC	P49840	GSK3A	S293	C300Y	300	Missense	distal	7	no	95.404	96.291	EPSD	COSMIC	72.838	Up-regulation
CMGC_GSK_GSK3A_ST	P01106	MYC	P49840	GSK3A	S293	P290T	290	Missense	distal	-3	no	95.404	95.917	EPSD	COSMIC	72.838	Up-regulation
CMGC_GSK_GSK3A_ST	P01106	MYC	P49840	GSK3A	S293	H287Q	287	Missense	distal	-6	no	95.404	95.287	EPSD	COSMIC	72.838	Down-regulation
CMGC_GSK_GSK3A_ST	P01106	MYC	P49840	GSK3A	S293	C300S	300	Missense	distal	7	no	95.404	96.216	EPSD	COSMIC	72.838	Up-regulation
CMGC_GSK_GSK3A_ST	P01106	MYC	P49840	GSK3A	S293	L295V	295	Missense	proximal	2	no	95.404	94.343	EPSD	COSMIC	72.838	Down-regulation
CMGC_GSK_GSK3A_ST	P01106	MYC	P49840	GSK3A	S293	P290H	290	Missense	distal	-3	no	95.404	95.241	EPSD	COSMIC	72.838	Down-regulation
CMGC_GSK_GSK3A_ST	P01106	MYC	P49840	GSK3A	S293	L297F	297	Missense	distal	4	no	95.404	78.522	EPSD	COSMIC	72.838	Down-regulation
CMGC_GSK_GSK3A_ST	P01106	MYC	P49840	GSK3A	S293	P290S	290	Missense	distal	-3	no	95.404	94.764	EPSD	COSMIC	72.838	Down-regulation
CMGC_GSK_GSK3A_ST	P01106	MYC	P49840	GSK3A	S293	S293R	293	Missense	central	0	yes	95.404	0.000	EPSD	COSMIC	72.838	Loss
CMGC_GSK_GSK3A_ST	P01106	MYC	P49840	GSK3A	S293	V296F	296	Missense	distal	3	no	95.404	92.159	EPSD	COSMIC	72.838	Down-regulation
CMGC_GSK_GSK3A_ST	P01106	MYC	P49840	GSK3A	S314	P313L	313	Missense	proximal	-1	no	77.637	76.482	EPSD	COSMIC	72.838	Down-regulation
CMGC_GSK_GSK3A_ST	P01106	MYC	P49840	GSK3A	S314	D318N	318	Missense	distal	4	no	77.637	75.590	EPSD	COSMIC	72.838	Down-regulation
CMGC_GSK_GSK3A_ST	P01106	MYC	P49840	GSK3A	S314	A321T	321	Missense	distal	7	no	77.637	78.025	EPSD	COSMIC	72.838	Up-regulation
CMGC_GSK_GSK3A_ST	P01106	MYC	P49840	GSK3A	S314	A311G	311	Missense	distal	-3	no	77.637	76.893	EPSD	COSMIC	72.838	Down-regulation
CMGC_GSK_GSK3A_ST	P01106	MYC	P49840	GSK3A	S314	P312L	312	Missense	proximal	-2	no	77.637	76.769	EPSD	COSMIC	72.838	Down-regulation
CMGC_GSK_GSK3A_ST	P01106	MYC	P49840	GSK3A	S314	A310T	310	Missense	distal	-4	no	77.637	83.392	EPSD	COSMIC	72.838	Up-regulation
CMGC_GSK_GSK3A_ST	P01106	MYC	P49840	GSK3A	S314	K317R	317	Missense	distal	3	no	77.637	75.695	EPSD	COSMIC	72.838	Down-regulation
CMGC_GSK_GSK3A_ST	P01106	MYC	P49840	GSK3A	S314	S314F	314	Missense	central	0	yes	77.637	0.000	EPSD	COSMIC	72.838	Loss
CMGC_GSK_GSK3A_ST	P01106	MYC	P49840	GSK3A	S314	H307Y	307	Missense	distal	-7	no	77.637	77.220	EPSD	COSMIC	72.838	Down-regulation
CMGC_GSK_GSK3A_ST	P01106	MYC	P49840	GSK3A	S314	A321V	321	Missense	distal	7	no	77.637	76.329	EPSD	COSMIC	72.838	Down-regulation
CMGC_GSK_GSK3A_ST	P01106	MYC	P49840	GSK3A	T315	P313L	313	Missense	proximal	-2	no	78.583	77.716	EPSD	COSMIC	72.838	Down-regulation
CMGC_GSK_GSK3A_ST	P01106	MYC	P49840	GSK3A	T315	D318N	318	Missense	distal	3	no	78.583	79.396	EPSD	COSMIC	72.838	Up-regulation
CMGC_GSK_GSK3A_ST	P01106	MYC	P49840	GSK3A	T315	A321T	321	Missense	distal	6	no	78.583	81.309	EPSD	COSMIC	72.838	Up-regulation
CMGC_GSK_GSK3A_ST	P01106	MYC	P49840	GSK3A	T315	A311G	311	Missense	distal	-4	no	78.583	78.692	EPSD	COSMIC	72.838	Up-regulation
CMGC_GSK_GSK3A_ST	P01106	MYC	P49840	GSK3A	T315	P312L	312	Missense	distal	-3	no	78.583	76.838	EPSD	COSMIC	72.838	Down-regulation
CMGC_GSK_GSK3A_ST	P01106	MYC	P49840	GSK3A	T315	A310T	310	Missense	distal	-5	no	78.583	77.854	EPSD	COSMIC	72.838	Down-regulation
CMGC_GSK_GSK3A_ST	P01106	MYC	P49840	GSK3A	T315	K317R	317	Missense	proximal	2	no	78.583	77.261	EPSD	COSMIC	72.838	Down-regulation
CMGC_GSK_GSK3A_ST	P01106	MYC	P49840	GSK3A	T315	S314F	314	Missense	proximal	-1	no	78.583	76.231	EPSD	COSMIC	72.838	Down-regulation
CMGC_GSK_GSK3A_ST	P01106	MYC	P49840	GSK3A	T315	A321V	321	Missense	distal	6	no	78.583	76.965	EPSD	COSMIC	72.838	Down-regulation
CMGC_GSK_GSK3A_ST	P01106	MYC	P49840	GSK3A	S329	V330L	330	Missense	proximal	1	no	65.701	75.139	EPSD	COSMIC	72.838	Gain
CMGC_GSK_GSK3A_ST	P01106	MYC	P49840	GSK3A	S344	S347F	347	Missense	distal	3	no	82.425	79.058	EPSD	COSMIC	72.838	Down-regulation
CMGC_GSK_GSK3A_ST	P01106	MYC	P49840	GSK3A	S344	E351K	351	Missense	distal	7	no	82.425	82.570	EPSD	COSMIC	72.838	Up-regulation
CMGC_GSK_GSK3A_ST	P01106	MYC	P49840	GSK3A	S344	S337T	337	Missense	distal	-7	no	82.425	83.273	EPSD	COSMIC	72.838	Up-regulation
CMGC_GSK_GSK3A_ST	P01106	MYC	P49840	GSK3A	S373	R378C	378	Missense	distal	5	no	75.713	62.019	EPSD	COSMIC	72.838	Loss
CMGC_GSK_GSK3A_ST	P01106	MYC	P49840	GSK3A	S373	F374L	374	Missense	proximal	1	no	75.713	77.398	EPSD	COSMIC	72.838	Up-regulation
CMGC_GSK_GSK3A_ST	P01106	MYC	P49840	GSK3A	S373	S373G	373	Missense	central	0	yes	75.713	0.000	EPSD	COSMIC	72.838	Loss
CMGC_GSK_GSK3A_ST	P01106	MYC	P49840	GSK3A	S373	R372L	372	Missense	proximal	-1	no	75.713	75.754	EPSD	COSMIC	72.838	Up-regulation
CMGC_GSK_GSK3A_ST	P01106	MYC	P49840	GSK3A	S373	E369K	369	Missense	distal	-4	no	75.713	73.919	EPSD	COSMIC	72.838	Down-regulation
CMGC_GSK_GSK3A_ST	P01106	MYC	P49840	GSK3A	S373	A376V	376	Missense	distal	3	no	75.713	74.948	EPSD	COSMIC	72.838	Down-regulation
CMGC_GSK_GSK3A_ST	P01106	MYC	P49840	GSK3A	S373	Q380H	380	Missense	distal	7	no	75.713	75.682	EPSD	COSMIC	72.838	Down-regulation
CMGC_GSK_GSK3A_ST	P01106	MYC	P49840	GSK3A	S373	S373R	373	Missense	central	0	yes	75.713	0.000	EPSD	COSMIC	72.838	Loss
CMGC_GSK_GSK3A_ST	P01106	MYC	P49840	GSK3A	S373	R372W	372	Missense	proximal	-1	no	75.713	75.775	EPSD	COSMIC	72.838	Up-regulation
CMGC_GSK_GSK3A_ST	P01106	MYC	P49840	GSK3A	S373	L377S	377	Missense	distal	4	no	75.713	81.123	EPSD	COSMIC	72.838	Up-regulation
CMGC_GSK_GSK3A_ST	P17812	CTPS1	P49840	GSK3A	S210	C216R	216	Missense	distal	6	no	70.955	75.118	EPSD	COSMIC	72.838	Gain
CMGC_GSK_GSK3A_ST	P17812	CTPS1	P49840	GSK3A	S562	C559Y	559	Missense	distal	-3	no	85.728	87.474	EPSD	COSMIC	72.838	Up-regulation
CMGC_GSK_GSK3A_ST	P17812	CTPS1	P49840	GSK3A	S562	D565G	565	Missense	distal	3	no	85.728	83.250	EPSD	COSMIC	72.838	Down-regulation
CMGC_GSK_GSK3A_ST	P17812	CTPS1	P49840	GSK3A	T566	R570K	570	Missense	distal	4	no	66.807	73.587	EPSD	COSMIC	72.838	Gain
CMGC_GSK_GSK3A_ST	P17812	CTPS1	P49840	GSK3A	S571	R570K	570	Missense	proximal	-1	no	81.787	81.127	PhosphoSitePlus	COSMIC	72.838	Down-regulation
CMGC_GSK_GSK3A_ST	P17812	CTPS1	P49840	GSK3A	S571	D565G	565	Missense	distal	-6	no	81.787	80.766	PhosphoSitePlus	COSMIC	72.838	Down-regulation
CMGC_GSK_GSK3A_ST	Q9BYG3	NIFK	P49840	GSK3A	S142	N135H	135	Missense	distal	-7	no	72.625	73.503	EPSD	COSMIC	72.838	Gain
CMGC_GSK_GSK3A_ST	Q9BYG3	NIFK	P49840	GSK3A	S218	R211C	211	Missense	distal	-7	no	81.303	80.631	EPSD	COSMIC	72.838	Down-regulation
CMGC_GSK_GSK3A_ST	Q9BYG3	NIFK	P49840	GSK3A	S218	P224S	224	Missense	distal	6	no	81.303	80.754	EPSD	COSMIC	72.838	Down-regulation
CMGC_GSK_GSK3A_ST	Q9BYG3	NIFK	P49840	GSK3A	T220	K226N	226	Missense	distal	6	no	81.181	81.449	EPSD	COSMIC	72.838	Up-regulation
CMGC_GSK_GSK3A_ST	Q9BYG3	NIFK	P49840	GSK3A	T220	P224S	224	Missense	distal	4	no	81.181	87.167	EPSD	COSMIC	72.838	Up-regulation
CMGC_GSK_GSK3A_ST	Q9BYG3	NIFK	P49840	GSK3A	T223	K226N	226	Missense	distal	3	no	84.948	85.404	EPSD	COSMIC	72.838	Up-regulation
CMGC_GSK_GSK3A_ST	Q9BYG3	NIFK	P49840	GSK3A	T223	P224S	224	Missense	proximal	1	no	84.948	69.256	EPSD	COSMIC	72.838	Loss
CMGC_GSK_GSK3A_ST	Q9BYG3	NIFK	P49840	GSK3A	S230	P235S	235	Missense	distal	5	no	82.284	76.727	PhosphoSitePlus;EPSD	COSMIC	72.838	Down-regulation
CMGC_GSK_GSK3A_ST	Q9BYG3	NIFK	P49840	GSK3A	S230	K226N	226	Missense	distal	-4	no	82.284	83.176	PhosphoSitePlus;EPSD	COSMIC	72.838	Up-regulation
CMGC_GSK_GSK3A_ST	Q9BYG3	NIFK	P49840	GSK3A	S230	P224S	224	Missense	distal	-6	no	82.284	82.230	PhosphoSitePlus;EPSD	COSMIC	72.838	Down-regulation
CMGC_GSK_GSK3A_ST	Q9BYG3	NIFK	P49840	GSK3A	T234	P235S	235	Missense	proximal	1	no	87.454	71.762	EPSD;PhosphoSitePlus	COSMIC	72.838	Loss
CMGC_GSK_GSK3A_ST	Q9BYG3	NIFK	P49840	GSK3A	T238	R245Q	245	Missense	distal	7	no	84.299	84.803	EPSD	COSMIC	72.838	Up-regulation
CMGC_GSK_GSK3A_ST	Q9BYG3	NIFK	P49840	GSK3A	T238	E243K	243	Missense	distal	5	no	84.299	80.222	EPSD	COSMIC	72.838	Down-regulation
CMGC_GSK_GSK3A_ST	Q9BYG3	NIFK	P49840	GSK3A	T238	P235S	235	Missense	distal	-3	no	84.299	83.659	EPSD	COSMIC	72.838	Down-regulation
CMGC_GSK_GSK3A_ST	Q9BYG3	NIFK	P49840	GSK3A	T238	E243D	243	Missense	distal	5	no	84.299	82.841	EPSD	COSMIC	72.838	Down-regulation
CMGC_GSK_GSK3A_ST	Q9BYG3	NIFK	P49840	GSK3A	S247	R245Q	245	Missense	proximal	-2	no	73.800	73.465	EPSD	COSMIC	72.838	Down-regulation
CMGC_GSK_GSK3A_ST	Q9BYG3	NIFK	P49840	GSK3A	S247	E243K	243	Missense	distal	-4	no	73.800	72.007	EPSD	COSMIC	72.838	Loss
CMGC_GSK_GSK3A_ST	Q9BYG3	NIFK	P49840	GSK3A	S247	E243D	243	Missense	distal	-4	no	73.800	73.791	EPSD	COSMIC	72.838	Down-regulation
CMGC_GSK_GSK3A_ST	Q9BYG3	NIFK	P49840	GSK3A	T279	H282R	282	Missense	distal	3	no	91.695	87.684	EPSD	COSMIC	72.838	Down-regulation
CMGC_GSK_GSK3A_ST	Q9BYG3	NIFK	P49840	GSK3A	T279	E272Q	272	Missense	distal	-7	no	91.695	90.925	EPSD	COSMIC	72.838	Down-regulation
CMGC_GSK_GSK3A_ST	Q13563	PKD2	P49840	GSK3A	S76	C82F	82	Missense	distal	6	no	88.748	86.948	PhosphoSitePlus	COSMIC	72.838	Down-regulation
CMGC_GSK_GSK3A_ST	Q13563	PKD2	P49840	GSK3A	S794	M800L	800	Missense	distal	6	no	73.531	71.868	EPSD	COSMIC	72.838	Loss
CMGC_GSK_GSK3A_ST	Q13563	PKD2	P49840	GSK3A	S794	D788G	788	Missense	distal	-6	no	73.531	72.510	EPSD	COSMIC	72.838	Loss
CMGC_GSK_GSK3A_ST	Q13563	PKD2	P49840	GSK3A	S794	E787K	787	Missense	distal	-7	no	73.531	74.120	EPSD	COSMIC	72.838	Up-regulation
CMGC_GSK_GSK3A_ST	Q13563	PKD2	P49840	GSK3A	S802	M800L	800	Missense	proximal	-2	no	73.096	73.262	EPSD	COSMIC	72.838	Up-regulation
CMGC_GSK_GSK3A_ST	Q13563	PKD2	P49840	GSK3A	S802	P806H	806	Missense	distal	4	no	73.096	51.045	EPSD	COSMIC	72.838	Loss
CMGC_GSK_GSK3A_ST	Q13563	PKD2	P49840	GSK3A	S804	M800L	800	Missense	distal	-4	no	75.424	66.267	EPSD	COSMIC	72.838	Loss
CMGC_GSK_GSK3A_ST	Q13563	PKD2	P49840	GSK3A	S804	P806H	806	Missense	proximal	2	no	75.424	74.102	EPSD	COSMIC	72.838	Down-regulation
CMGC_GSK_GSK3A_ST	Q13563	PKD2	P49840	GSK3A	S808	P806H	806	Missense	proximal	-2	no	78.504	78.251	EPSD	COSMIC	72.838	Down-regulation
CMGC_GSK_GSK3A_ST	Q13563	PKD2	P49840	GSK3A	S947	R940C	940	Missense	distal	-7	no	77.296	76.624	EPSD	COSMIC	72.838	Down-regulation
CMGC_GSK_GSK3A_ST	Q07817	BCL2L1	P49840	GSK3A	S62	A64T	64	Missense	proximal	2	no	89.682	91.357	PhosphoSitePlus	COSMIC;GDSC;CCLE	72.838	Up-regulation
CMGC_GSK_GSK3A_ST	Q07817	BCL2L1	P49840	GSK3A	S62	A60V	60	Missense	proximal	-2	no	89.682	88.933	PhosphoSitePlus	COSMIC;GDSC;CCLE	72.838	Down-regulation
CMGC_GSK_GSK3A_ST	O15084	ANKRD28	P49840	GSK3A	T357	L358P	358	Missense	proximal	1	no	60.389	74.441	EPSD	COSMIC	72.838	Gain
CMGC_GSK_GSK3A_ST	O15084	ANKRD28	P49840	GSK3A	S537	S537L	537	Missense	central	0	yes	74.958	0.000	EPSD	COSMIC	72.838	Loss
CMGC_GSK_GSK3A_ST	O15084	ANKRD28	P49840	GSK3A	S988	V986I	986	Missense	proximal	-2	no	75.816	75.984	EPSD	COSMIC	72.838	Up-regulation
CMGC_GSK_GSK3A_ST	O15084	ANKRD28	P49840	GSK3A	S988	M984I	984	Missense	distal	-4	no	75.816	67.148	EPSD	COSMIC	72.838	Loss
CMGC_GSK_GSK3A_ST	O15084	ANKRD28	P49840	GSK3A	S990	V986I	986	Missense	distal	-4	no	79.689	79.682	EPSD	COSMIC	72.838	Down-regulation
CMGC_GSK_GSK3A_ST	O15084	ANKRD28	P49840	GSK3A	S990	M984I	984	Missense	distal	-6	no	79.689	79.481	EPSD	COSMIC	72.838	Down-regulation
CMGC_GSK_GSK3A_ST	O15084	ANKRD28	P49840	GSK3A	S1007	R1002H	1002	Missense	distal	-5	no	83.117	83.318	PhosphoSitePlus	COSMIC;GDSC	72.838	Up-regulation
CMGC_GSK_GSK3A_ST	P13051	UNG	P49840	GSK3A	S23	A16S	16	Missense	distal	-7	no	82.962	82.003	EPSD	COSMIC	72.838	Down-regulation
CMGC_GSK_GSK3A_ST	P13051	UNG	P49840	GSK3A	S23	R19L	19	Missense	distal	-4	no	82.962	80.056	EPSD	COSMIC	72.838	Down-regulation
CMGC_GSK_GSK3A_ST	P13051	UNG	P49840	GSK3A	T60	P61S	61	Missense	proximal	1	no	98.672	82.979	EPSD;PhosphoSitePlus	COSMIC	72.838	Down-regulation
CMGC_GSK_GSK3A_ST	P13051	UNG	P49840	GSK3A	S63	P61S	61	Missense	proximal	-2	no	82.301	82.149	EPSD	COSMIC	72.838	Down-regulation
CMGC_GSK_GSK3A_ST	P13051	UNG	P49840	GSK3A	S64	P61S	61	Missense	distal	-3	no	94.217	93.578	PhosphoSitePlus;EPSD	COSMIC	72.838	Down-regulation
CMGC_GSK_GSK3A_ST	P13051	UNG	P49840	GSK3A	S279	Q274L	274	Missense	distal	-5	no	86.903	84.578	EPSD	COSMIC;CCLE	72.838	Down-regulation
CMGC_GSK_GSK3A_ST	P13051	UNG	P49840	GSK3A	S279	L281F	281	Missense	proximal	2	no	86.903	83.330	EPSD	COSMIC	72.838	Down-regulation
CMGC_GSK_GSK3A_ST	P13051	UNG	P49840	GSK3A	S279	V272G	272	Missense	distal	-7	no	86.903	87.013	EPSD	COSMIC	72.838	Up-regulation
CMGC_GSK_GSK3A_ST	P13051	UNG	P49840	GSK3A	S279	H277R	277	Missense	proximal	-2	no	86.903	87.367	EPSD	COSMIC	72.838	Up-regulation
CMGC_GSK_GSK3A_ST	Q9Y4H4	GPSM3	P49840	GSK3A	S35	R31Q	31	Missense	distal	-4	no	83.101	80.048	PhosphoSitePlus	COSMIC	72.838	Down-regulation
CMGC_GSK_GSK3A_ST	Q9Y4H4	GPSM3	P49840	GSK3A	S39	T45K	45	Missense	distal	6	no	86.623	86.978	EPSD	COSMIC	72.838	Up-regulation
CMGC_GSK_GSK3A_ST	Q9Y4H4	GPSM3	P49840	GSK3A	T45	T48K	48	Missense	distal	3	no	79.014	79.219	EPSD	COSMIC	72.838	Up-regulation
CMGC_GSK_GSK3A_ST	Q9Y4H4	GPSM3	P49840	GSK3A	T45	T45K	45	Missense	central	0	yes	79.014	0.000	EPSD	COSMIC	72.838	Loss
CMGC_GSK_GSK3A_ST	Q9Y4H4	GPSM3	P49840	GSK3A	S74	S74F	74	Missense	central	0	yes	75.614	0.000	EPSD	COSMIC	72.838	Loss
CMGC_GSK_GSK3A_ST	Q9Y4H4	GPSM3	P49840	GSK3A	S74	R75G	75	Missense	proximal	1	no	75.614	73.791	EPSD	COSMIC	72.838	Down-regulation
CMGC_GSK_GSK3A_ST	Q9Y4H4	GPSM3	P49840	GSK3A	S74	Q80K	80	Missense	distal	6	no	75.614	74.240	EPSD	COSMIC	72.838	Down-regulation
CMGC_GSK_GSK3A_ST	Q9Y4H4	GPSM3	P49840	GSK3A	T86	Q80K	80	Missense	distal	-6	no	73.753	73.529	EPSD	COSMIC	72.838	Down-regulation
CMGC_GSK_GSK3A_ST	Q9NZ72	STMN3	P49840	GSK3A	S60	D63H	63	Missense	distal	3	no	87.763	90.190	PhosphoSitePlus	COSMIC	72.838	Up-regulation
CMGC_GSK_GSK3A_ST	Q9NZ72	STMN3	P49840	GSK3A	S60	D63N	63	Missense	distal	3	no	87.763	88.577	PhosphoSitePlus	COSMIC	72.838	Up-regulation
CMGC_GSK_GSK3A_ST	Q9NZ72	STMN3	P49840	GSK3A	S60	D63E	63	Missense	distal	3	no	87.763	87.616	PhosphoSitePlus	COSMIC	72.838	Down-regulation
CMGC_GSK_GSK3A_ST	Q9NZ72	STMN3	P49840	GSK3A	S60	E55K	55	Missense	distal	-5	no	87.763	87.653	PhosphoSitePlus	COSMIC	72.838	Down-regulation
CMGC_GSK_GSK3A_ST	Q9NZ72	STMN3	P49840	GSK3A	S65	P69H	69	Missense	distal	4	no	73.156	51.105	EPSD	COSMIC;GDSC;CCLE	72.838	Loss
CMGC_GSK_GSK3A_ST	Q9NZ72	STMN3	P49840	GSK3A	S65	D63H	63	Missense	proximal	-2	no	73.156	73.941	EPSD	COSMIC	72.838	Up-regulation
CMGC_GSK_GSK3A_ST	Q9NZ72	STMN3	P49840	GSK3A	S65	D63N	63	Missense	proximal	-2	no	73.156	73.157	EPSD	COSMIC	72.838	Up-regulation
CMGC_GSK_GSK3A_ST	Q9NZ72	STMN3	P49840	GSK3A	S65	D63E	63	Missense	proximal	-2	no	73.156	73.558	EPSD	COSMIC	72.838	Up-regulation
CMGC_GSK_GSK3A_ST	Q9NZ72	STMN3	P49840	GSK3A	S65	S72F	72	Missense	distal	7	no	73.156	70.736	EPSD	COSMIC	72.838	Loss
CMGC_GSK_GSK3A_ST	Q9NZ72	STMN3	P49840	GSK3A	S68	P69H	69	Missense	proximal	1	no	77.617	51.203	EPSD	COSMIC;GDSC;CCLE	72.838	Loss
CMGC_GSK_GSK3A_ST	Q9NZ72	STMN3	P49840	GSK3A	S68	D63H	63	Missense	distal	-5	no	77.617	79.251	EPSD	COSMIC	72.838	Up-regulation
CMGC_GSK_GSK3A_ST	Q9NZ72	STMN3	P49840	GSK3A	S68	D63N	63	Missense	distal	-5	no	77.617	80.082	EPSD	COSMIC	72.838	Up-regulation
CMGC_GSK_GSK3A_ST	Q9NZ72	STMN3	P49840	GSK3A	S68	D63E	63	Missense	distal	-5	no	77.617	79.930	EPSD	COSMIC	72.838	Up-regulation
CMGC_GSK_GSK3A_ST	Q9NZ72	STMN3	P49840	GSK3A	S68	S72F	72	Missense	distal	4	no	77.617	55.326	EPSD	COSMIC	72.838	Loss
CMGC_GSK_GSK3A_ST	Q9NZ72	STMN3	P49840	GSK3A	S73	P69H	69	Missense	distal	-4	no	86.291	89.474	EPSD	COSMIC;GDSC;CCLE	72.838	Up-regulation
CMGC_GSK_GSK3A_ST	Q9NZ72	STMN3	P49840	GSK3A	S73	S72F	72	Missense	proximal	-1	no	86.291	83.940	EPSD	COSMIC	72.838	Down-regulation
CMGC_GSK_GSK3A_ST	Q16555	DPYSL2	P49840	GSK3A	T74	V72I	72	Missense	proximal	-2	no	73.917	74.085	EPSD	COSMIC	72.838	Up-regulation
CMGC_GSK_GSK3A_ST	Q16555	DPYSL2	P49840	GSK3A	T74	R75S	75	Missense	proximal	1	no	73.917	66.877	EPSD	COSMIC	72.838	Loss
CMGC_GSK_GSK3A_ST	Q16555	DPYSL2	P49840	GSK3A	T74	G68R	68	Missense	distal	-6	no	73.917	74.075	EPSD	COSMIC;GDSC;CCLE	72.838	Up-regulation
CMGC_GSK_GSK3A_ST	Q16555	DPYSL2	P49840	GSK3A	T303	L307S	307	Missense	distal	4	no	70.546	75.956	EPSD	COSMIC	72.838	Gain
CMGC_GSK_GSK3A_ST	Q16555	DPYSL2	P49840	GSK3A	S304	A298T	298	Missense	distal	-6	no	92.097	91.515	EPSD	COSMIC	72.838	Down-regulation
CMGC_GSK_GSK3A_ST	Q16555	DPYSL2	P49840	GSK3A	S304	P305L	305	Missense	proximal	1	no	92.097	78.046	EPSD	COSMIC	72.838	Down-regulation
CMGC_GSK_GSK3A_ST	Q16555	DPYSL2	P49840	GSK3A	S304	P305T	305	Missense	proximal	1	no	92.097	77.446	EPSD	COSMIC	72.838	Down-regulation
CMGC_GSK_GSK3A_ST	Q16555	DPYSL2	P49840	GSK3A	S304	V302F	302	Missense	proximal	-2	no	92.097	91.931	EPSD	COSMIC	72.838	Down-regulation
CMGC_GSK_GSK3A_ST	Q16555	DPYSL2	P49840	GSK3A	S304	L307S	307	Missense	distal	3	no	92.097	94.625	EPSD	COSMIC	72.838	Up-regulation
CMGC_GSK_GSK3A_ST	Q16555	DPYSL2	P49840	GSK3A	S308	P305L	305	Missense	distal	-3	no	79.042	77.297	EPSD	COSMIC	72.838	Down-regulation
CMGC_GSK_GSK3A_ST	Q16555	DPYSL2	P49840	GSK3A	S308	P305T	305	Missense	distal	-3	no	79.042	79.555	EPSD	COSMIC	72.838	Up-regulation
CMGC_GSK_GSK3A_ST	Q16555	DPYSL2	P49840	GSK3A	S308	V302F	302	Missense	distal	-6	no	79.042	79.639	EPSD	COSMIC	72.838	Up-regulation
CMGC_GSK_GSK3A_ST	Q16555	DPYSL2	P49840	GSK3A	S308	L307S	307	Missense	proximal	-1	no	79.042	79.300	EPSD	COSMIC	72.838	Up-regulation
CMGC_GSK_GSK3A_ST	Q16555	DPYSL2	P49840	GSK3A	S465	P470S	470	Missense	distal	5	no	80.668	75.111	EPSD	COSMIC	72.838	Down-regulation
CMGC_GSK_GSK3A_ST	Q16555	DPYSL2	P49840	GSK3A	S465	H460D	460	Missense	distal	-5	no	80.668	79.034	EPSD	COSMIC	72.838	Down-regulation
CMGC_GSK_GSK3A_ST	Q16555	DPYSL2	P49840	GSK3A	S465	E463K	463	Missense	proximal	-2	no	80.668	82.029	EPSD	COSMIC	72.838	Up-regulation
CMGC_GSK_GSK3A_ST	Q16555	DPYSL2	P49840	GSK3A	T509	V506A	506	Missense	distal	-3	no	92.986	93.181	EPSD	COSMIC	72.838	Up-regulation
CMGC_GSK_GSK3A_ST	Q16555	DPYSL2	P49840	GSK3A	S537	L534F	534	Missense	distal	-3	no	81.239	81.115	EPSD	COSMIC	72.838	Down-regulation
CMGC_GSK_GSK3A_ST	Q16555	DPYSL2	P49840	GSK3A	S537	R532Q	532	Missense	distal	-5	no	81.239	83.588	EPSD	COSMIC;GDSC;CCLE	72.838	Up-regulation
CMGC_GSK_GSK3A_ST	Q16555	DPYSL2	P49840	GSK3A	S537	G538E	538	Missense	proximal	1	no	81.239	73.189	EPSD	COSMIC	72.838	Down-regulation
CMGC_GSK_GSK3A_ST	Q16555	DPYSL2	P49840	GSK3A	S537	G543D	543	Missense	distal	6	no	81.239	81.954	EPSD	COSMIC;GDSC	72.838	Up-regulation
CMGC_GSK_GSK3A_ST	Q16555	DPYSL2	P49840	GSK3A	S542	N549S	549	Missense	distal	7	no	80.714	81.363	EPSD	COSMIC	72.838	Up-regulation
CMGC_GSK_GSK3A_ST	Q16555	DPYSL2	P49840	GSK3A	S542	I546T	546	Missense	distal	4	no	80.714	84.287	EPSD	COSMIC	72.838	Up-regulation
CMGC_GSK_GSK3A_ST	Q16555	DPYSL2	P49840	GSK3A	S542	G538E	538	Missense	distal	-4	no	80.714	83.881	EPSD	COSMIC	72.838	Up-regulation
CMGC_GSK_GSK3A_ST	Q16555	DPYSL2	P49840	GSK3A	S542	G543D	543	Missense	proximal	1	no	80.714	70.544	EPSD	COSMIC;GDSC	72.838	Loss
Atypical_PDHK_PDHK_PDK2_ST	P08559	PDHA1	Q15119	PDK2	S130	E133K	133	Missense	distal	3	no	1.823	1.832	EPSD	COSMIC	1.129	Up-regulation
Atypical_PDHK_PDHK_PDK2_ST	P08559	PDHA1	Q15119	PDK2	S130	R127W	127	Missense	distal	-3	no	1.823	1.825	EPSD	COSMIC	1.129	Up-regulation
Atypical_PDHK_PDHK_PDK2_ST	P08559	PDHA1	Q15119	PDK2	S130	R132Q	132	Missense	proximal	2	no	1.823	1.813	EPSD	COSMIC	1.129	Down-regulation
Atypical_PDHK_PDHK_PDK2_ST	P08559	PDHA1	Q15119	PDK2	S130	A136T	136	Missense	distal	6	no	1.823	1.739	EPSD	COSMIC	1.129	Down-regulation
Atypical_PDHK_PDHK_PDK2_ST	P08559	PDHA1	Q15119	PDK2	S130	L135I	135	Missense	distal	5	no	1.823	1.859	EPSD	COSMIC	1.129	Up-regulation
Atypical_PDHK_PDHK_PDK2_ST	P08559	PDHA1	Q15119	PDK2	S152	S152L	152	Missense	central	0	yes	2.232	0.000	EPSD	COSMIC	1.129	Loss
Atypical_PDHK_PDHK_PDK2_ST	P08559	PDHA1	Q15119	PDK2	S152	M155V	155	Missense	distal	3	no	2.232	2.235	EPSD	COSMIC	1.129	Up-regulation
Atypical_PDHK_PDHK_PDK2_ST	P08559	PDHA1	Q15119	PDK2	S152	A146S	146	Missense	distal	-6	no	2.232	2.206	EPSD	COSMIC	1.129	Down-regulation
Atypical_PDHK_PDHK_PDK2_ST	P08559	PDHA1	Q15119	PDK2	S232	S239F	239	Missense	distal	7	no	4.198	4.185	EPSD;PhosphoSitePlus	COSMIC	1.129	Down-regulation
Atypical_PDHK_PDHK_PDK2_ST	P08559	PDHA1	Q15119	PDK2	S232	R226H	226	Missense	distal	-6	no	4.198	4.346	EPSD;PhosphoSitePlus	COSMIC	1.129	Up-regulation
Atypical_PDHK_PDHK_PDK2_ST	P08559	PDHA1	Q15119	PDK2	S232	S232F	232	Missense	central	0	yes	4.198	0.000	EPSD;PhosphoSitePlus	COSMIC	1.129	Loss
Atypical_PDHK_PDHK_PDK2_ST	P08559	PDHA1	Q15119	PDK2	S232	E234K	234	Missense	proximal	2	no	4.198	4.176	EPSD;PhosphoSitePlus	COSMIC	1.129	Down-regulation
Atypical_PDHK_PDHK_PDK2_ST	P08559	PDHA1	Q15119	PDK2	T240	D247N	247	Missense	distal	7	no	1.294	1.307	EPSD	COSMIC	1.129	Up-regulation
Atypical_PDHK_PDHK_PDK2_ST	P08559	PDHA1	Q15119	PDK2	T240	G246D	246	Missense	distal	6	no	1.294	1.469	EPSD	COSMIC	1.129	Up-regulation
Atypical_PDHK_PDHK_PDK2_ST	P08559	PDHA1	Q15119	PDK2	T240	Y243H	243	Missense	distal	3	no	1.294	1.278	EPSD	COSMIC	1.129	Down-regulation
Atypical_PDHK_PDHK_PDK2_ST	P08559	PDHA1	Q15119	PDK2	T240	E234K	234	Missense	distal	-6	no	1.294	1.261	EPSD	COSMIC	1.129	Down-regulation
Atypical_PDHK_PDHK_PDK2_ST	P08559	PDHA1	Q15119	PDK2	T286	M282L	282	Missense	distal	-4	no	0.974	1.170	EPSD	COSMIC	1.129	Gain
Atypical_PDHK_PDHK_PDK2_ST	P08559	PDHA1	Q15119	PDK2	S293	Y287H	287	Missense	distal	-6	no	5.073	4.850	PhosphoSitePlus;EPSD	COSMIC	1.129	Down-regulation
Atypical_PDHK_PDHK_PDK2_ST	P08559	PDHA1	Q15119	PDK2	S293	R288C	288	Missense	distal	-5	no	5.073	5.074	PhosphoSitePlus;EPSD	COSMIC	1.129	Up-regulation
Atypical_PDHK_PDHK_PDK2_ST	P08559	PDHA1	Q15119	PDK2	S300	R302S	302	Missense	proximal	2	no	5.490	5.509	EPSD;PhosphoSitePlus	COSMIC	1.129	Up-regulation
Atypical_PDHK_PDHK_PDK2_ST	P08559	PDHA1	Q15119	PDK2	S300	R304Q	304	Missense	distal	4	no	5.490	5.466	EPSD;PhosphoSitePlus	COSMIC;GDSC;CCLE	1.129	Down-regulation
Atypical_PDHK_PDHK_PDK2_ST	P08559	PDHA1	Q15119	PDK2	S300	R302C	302	Missense	proximal	2	no	5.490	5.493	EPSD;PhosphoSitePlus	COSMIC	1.129	Up-regulation
Atypical_PDHK_PDHK_PDK2_ST	P08559	PDHA1	Q15119	PDK2	S300	R302L	302	Missense	proximal	2	no	5.490	5.504	EPSD;PhosphoSitePlus	COSMIC	1.129	Up-regulation
Atypical_PDHK_PDHK_PDK2_ST	P29803	PDHA2	Q15119	PDK2	S128	G126R	126	Missense	proximal	-2	no	1.535	0.671	EPSD	COSMIC	1.129	Loss
Atypical_PDHK_PDHK_PDK2_ST	P29803	PDHA2	Q15119	PDK2	S128	R130Q	130	Missense	proximal	2	no	1.535	1.525	EPSD	COSMIC	1.129	Down-regulation
Atypical_PDHK_PDHK_PDK2_ST	P29803	PDHA2	Q15119	PDK2	S128	R125W	125	Missense	distal	-3	no	1.535	1.536	EPSD	COSMIC	1.129	Up-regulation
Atypical_PDHK_PDHK_PDK2_ST	P29803	PDHA2	Q15119	PDK2	S128	V129L	129	Missense	proximal	1	no	1.535	0.977	EPSD	COSMIC;GDSC;CCLE	1.129	Loss
Atypical_PDHK_PDHK_PDK2_ST	P29803	PDHA2	Q15119	PDK2	S128	L133I	133	Missense	distal	5	no	1.535	1.570	EPSD	COSMIC	1.129	Up-regulation
Atypical_PDHK_PDHK_PDK2_ST	P29803	PDHA2	Q15119	PDK2	S150	Y154H	154	Missense	distal	4	no	2.111	2.155	EPSD	COSMIC;GDSC;CCLE	1.129	Up-regulation
Atypical_PDHK_PDHK_PDK2_ST	P29803	PDHA2	Q15119	PDK2	S150	A144T	144	Missense	distal	-6	no	2.111	2.080	EPSD	COSMIC	1.129	Down-regulation
Atypical_PDHK_PDHK_PDK2_ST	P29803	PDHA2	Q15119	PDK2	S230	A236V	236	Missense	distal	6	no	2.450	2.473	EPSD	COSMIC	1.129	Up-regulation
Atypical_PDHK_PDHK_PDK2_ST	P29803	PDHA2	Q15119	PDK2	T284	R286H	286	Missense	proximal	2	no	1.160	1.138	EPSD	COSMIC	1.129	Down-regulation
Atypical_PDHK_PDHK_PDK2_ST	P29803	PDHA2	Q15119	PDK2	T284	M280T	280	Missense	distal	-4	no	1.160	1.314	EPSD	COSMIC	1.129	Up-regulation
Atypical_PDHK_PDHK_PDK2_ST	P29803	PDHA2	Q15119	PDK2	T284	T284I	284	Missense	central	0	yes	1.160	0.000	EPSD	COSMIC	1.129	Loss
Atypical_PDHK_PDHK_PDK2_ST	P29803	PDHA2	Q15119	PDK2	T284	L282R	282	Missense	proximal	-2	no	1.160	1.444	EPSD	COSMIC	1.129	Up-regulation
Atypical_PDHK_PDHK_PDK2_ST	P29803	PDHA2	Q15119	PDK2	T284	T284P	284	Missense	central	0	yes	1.160	0.000	EPSD	COSMIC	1.129	Loss
Atypical_PDHK_PDHK_PDK2_ST	P29803	PDHA2	Q15119	PDK2	T284	P277L	277	Missense	distal	-7	no	1.160	1.086	EPSD	COSMIC	1.129	Loss
Atypical_PDHK_PDHK_PDK2_ST	P29803	PDHA2	Q15119	PDK2	S291	R286H	286	Missense	distal	-5	no	4.883	4.886	EPSD;PhosphoSitePlus	COSMIC	1.129	Up-regulation
Atypical_PDHK_PDHK_PDK2_ST	P29803	PDHA2	Q15119	PDK2	S291	T284I	284	Missense	distal	-7	no	4.883	4.901	EPSD;PhosphoSitePlus	COSMIC	1.129	Up-regulation
Atypical_PDHK_PDHK_PDK2_ST	P29803	PDHA2	Q15119	PDK2	S291	T284P	284	Missense	distal	-7	no	4.883	4.932	EPSD;PhosphoSitePlus	COSMIC	1.129	Up-regulation
Atypical_PDHK_PDHK_PDK2_ST	P29803	PDHA2	Q15119	PDK2	S291	D294Y	294	Missense	distal	3	no	4.883	4.898	EPSD;PhosphoSitePlus	COSMIC;GDSC;CCLE	1.129	Up-regulation
Atypical_PDHK_PDHK_PDK2_ST	P29803	PDHA2	Q15119	PDK2	S293	D294Y	294	Missense	proximal	1	no	-0.715	1.142	EPSD	COSMIC;GDSC;CCLE	1.129	Gain
Atypical_PDHK_PDHK_PDK2_ST	P29803	PDHA2	Q15119	PDK2	S298	E304K	304	Missense	distal	6	no	5.732	5.564	PhosphoSitePlus;EPSD	COSMIC	1.129	Down-regulation
Atypical_PDHK_PDHK_PDK2_ST	P29803	PDHA2	Q15119	PDK2	S298	D294Y	294	Missense	distal	-4	no	5.732	5.595	PhosphoSitePlus;EPSD	COSMIC;GDSC;CCLE	1.129	Down-regulation
CAMK_TSSK_TSSK4_ST	P16220	CREB1	Q6SA08	TSSK4	S98	S103N	103	Missense	distal	5	no	1.808	2.043	EPSD	COSMIC	1.711	Up-regulation
CAMK_TSSK_TSSK4_ST	P16220	CREB1	Q6SA08	TSSK4	S98	R95I	95	Missense	distal	-3	no	1.808	1.784	EPSD	COSMIC	1.711	Down-regulation
CAMK_TSSK_TSSK4_ST	P16220	CREB1	Q6SA08	TSSK4	S98	I102M	102	Missense	distal	4	no	1.808	1.556	EPSD	COSMIC	1.711	Loss
CAMK_TSSK_TSSK4_ST	P16220	CREB1	Q6SA08	TSSK4	S111	S117N	117	Missense	distal	6	no	1.918	1.873	EPSD	COSMIC	1.711	Down-regulation
CAMK_TSSK_TSSK4_ST	P16220	CREB1	Q6SA08	TSSK4	S111	V118L	118	Missense	distal	7	no	1.918	1.844	EPSD	COSMIC	1.711	Down-regulation
CAMK_TSSK_TSSK4_ST	P16220	CREB1	Q6SA08	TSSK4	S111	E109K	109	Missense	proximal	-2	no	1.918	1.910	EPSD	COSMIC	1.711	Down-regulation
CAMK_TSSK_TSSK4_ST	P16220	CREB1	Q6SA08	TSSK4	S111	V118I	118	Missense	distal	7	no	1.918	1.881	EPSD	COSMIC	1.711	Down-regulation
CAMK_TSSK_TSSK4_ST	P16220	CREB1	Q6SA08	TSSK4	S133	L128R	128	Missense	distal	-5	no	8.812	8.903	PhosphoSitePlus	COSMIC	1.711	Up-regulation
CAMK_TSSK_TSSK4_ST	P16220	CREB1	Q6SA08	TSSK4	T251	R255H	255	Missense	distal	4	no	2.528	2.513	EPSD	COSMIC	1.711	Down-regulation
CAMK_TSSK_TSSK4_ST	P16220	CREB1	Q6SA08	TSSK4	T251	A257T	257	Missense	distal	6	no	2.528	2.535	EPSD	COSMIC	1.711	Up-regulation
CAMK_TSSK_TSSK4_ST	P16220	CREB1	Q6SA08	TSSK4	T259	I262V	262	Missense	distal	3	no	2.835	3.068	EPSD	COSMIC	1.711	Up-regulation
CAMK_TSSK_TSSK4_ST	P16220	CREB1	Q6SA08	TSSK4	T259	R255H	255	Missense	distal	-4	no	2.835	2.931	EPSD	COSMIC	1.711	Up-regulation
CAMK_TSSK_TSSK4_ST	P16220	CREB1	Q6SA08	TSSK4	T259	A257T	257	Missense	proximal	-2	no	2.835	2.831	EPSD	COSMIC	1.711	Down-regulation
CAMK_TSSK_TSSK4_ST	P16220	CREB1	Q6SA08	TSSK4	T259	P264T	264	Missense	distal	5	no	2.835	2.781	EPSD	COSMIC;GDSC;CCLE	1.711	Down-regulation
TK_Met_MET_Y	P09874	PARP1	P08581	MET	Y117	T124M	124	Missense	distal	7	no	46.090	46.081	EPSD	COSMIC	27.257	Down-regulation
TK_Met_MET_Y	P09874	PARP1	P08581	MET	Y176	R173Q	173	Missense	distal	-3	no	30.180	30.938	EPSD	COSMIC	27.257	Up-regulation
TK_Met_MET_Y	P09874	PARP1	P08581	MET	Y176	E169K	169	Missense	distal	-7	no	30.180	29.206	EPSD	COSMIC	27.257	Down-regulation
TK_Met_MET_Y	P09874	PARP1	P08581	MET	Y176	R173W	173	Missense	distal	-3	no	30.180	26.833	EPSD	COSMIC	27.257	Loss
TK_Met_MET_Y	P09874	PARP1	P08581	MET	Y176	G183S	183	Missense	distal	7	no	30.180	30.573	EPSD	COSMIC	27.257	Up-regulation
TK_Met_MET_Y	P09874	PARP1	P08581	MET	Y176	F172V	172	Missense	distal	-4	no	30.180	32.550	EPSD	COSMIC	27.257	Up-regulation
TK_Met_MET_Y	P09874	PARP1	P08581	MET	Y309	T316A	316	Missense	distal	7	no	30.165	30.141	EPSD	COSMIC	27.257	Down-regulation
TK_Met_MET_Y	P09874	PARP1	P08581	MET	Y309	D314N	314	Missense	distal	5	no	30.165	30.382	EPSD	COSMIC	27.257	Up-regulation
TK_Met_MET_Y	P09874	PARP1	P08581	MET	Y309	V315I	315	Missense	distal	6	no	30.165	29.361	EPSD	COSMIC	27.257	Down-regulation
TK_Met_MET_Y	P09874	PARP1	P08581	MET	Y737	T738I	738	Missense	proximal	1	no	27.512	25.877	EPSD	COSMIC	27.257	Loss
TK_Met_MET_Y	P09874	PARP1	P08581	MET	Y737	P741S	741	Missense	distal	4	no	27.512	30.243	EPSD	COSMIC	27.257	Up-regulation
TK_Met_MET_Y	P09874	PARP1	P08581	MET	Y737	D743Y	743	Missense	distal	6	no	27.512	25.192	EPSD	COSMIC	27.257	Loss
TK_Met_MET_Y	P09874	PARP1	P08581	MET	Y907	G913E	913	Missense	distal	6	no	35.103	36.744	PhosphoSitePlus	COSMIC	27.257	Up-regulation
TK_Met_MET_Y	P09874	PARP1	P08581	MET	Y907	T910A	910	Missense	distal	3	no	35.103	35.323	PhosphoSitePlus	COSMIC;GDSC;CCLE	27.257	Up-regulation
TK_Met_MET_Y	P29353	SHC1	P08581	MET	Y427	V430I	430	Missense	distal	3	no	55.536	46.327	PhosphoSitePlus	COSMIC	27.257	Down-regulation
TK_Met_MET_Y	P29353	SHC1	P08581	MET	Y427	S426C	426	Missense	proximal	-1	no	55.536	51.978	PhosphoSitePlus	COSMIC	27.257	Down-regulation
TK_Met_MET_Y	P29353	SHC1	P08581	MET	Y427	S426P	426	Missense	proximal	-1	no	55.536	54.672	PhosphoSitePlus	COSMIC	27.257	Down-regulation
TK_Met_MET_Y	P08581	MET	P08581	MET	Y745	P742A	742	Missense	distal	-3	no	25.839	29.635	EPSD	COSMIC	27.257	Gain
TK_Met_MET_Y	P08581	MET	P08581	MET	Y835	L833M	833	Missense	proximal	-2	no	19.811	27.586	EPSD	COSMIC	27.257	Gain
TK_Met_MET_Y	P08581	MET	P08581	MET	Y1003	T1006I	1006	Missense	distal	3	no	28.602	24.260	EPSD	COSMIC	27.257	Loss
TK_Met_MET_Y	P08581	MET	P08581	MET	Y1003	E1009K	1009	Missense	distal	6	no	28.602	28.232	EPSD	COSMIC	27.257	Down-regulation
TK_Met_MET_Y	P08581	MET	P08581	MET	Y1003	D1010H	1010	Missense	distal	7	no	28.602	28.324	EPSD	COSMIC	27.257	Down-regulation
TK_Met_MET_Y	P08581	MET	P08581	MET	Y1003	P1008A	1008	Missense	distal	5	no	28.602	26.897	EPSD	COSMIC	27.257	Loss
TK_Met_MET_Y	P08581	MET	P08581	MET	Y1003	D1010N	1010	Missense	distal	7	no	28.602	28.456	EPSD	COSMIC	27.257	Down-regulation
TK_Met_MET_Y	P08581	MET	P08581	MET	Y1003	Y1003C	1003	Missense	central	0	yes	28.602	0.000	EPSD	COSMIC	27.257	Loss
TK_Met_MET_Y	P08581	MET	P08581	MET	Y1003	D1010Y	1010	Missense	distal	7	no	28.602	28.243	EPSD	COSMIC	27.257	Down-regulation
TK_Met_MET_Y	P08581	MET	P08581	MET	Y1003	V1001I	1001	Missense	proximal	-2	no	28.602	27.607	EPSD	COSMIC	27.257	Down-regulation
TK_Met_MET_Y	P08581	MET	P08581	MET	Y1003	Y1003N	1003	Missense	central	0	yes	28.602	0.000	EPSD	COSMIC	27.257	Loss
TK_Met_MET_Y	P08581	MET	P08581	MET	Y1003	S1000F	1000	Missense	distal	-3	no	28.602	13.552	EPSD	COSMIC	27.257	Loss
TK_Met_MET_Y	P08581	MET	P08581	MET	Y1003	Y1003S	1003	Missense	central	0	yes	28.602	0.000	EPSD	COSMIC	27.257	Loss
TK_Met_MET_Y	P08581	MET	P08581	MET	Y1003	N998D	998	Missense	distal	-5	no	28.602	29.637	EPSD	COSMIC	27.257	Up-regulation
TK_Met_MET_Y	P08581	MET	P08581	MET	Y1003	Y1003F	1003	Missense	central	0	yes	28.602	0.000	EPSD	COSMIC	27.257	Loss
TK_Met_MET_Y	P08581	MET	P08581	MET	Y1003	E999K	999	Missense	distal	-4	no	28.602	26.789	EPSD	COSMIC	27.257	Loss
TK_Met_MET_Y	P08581	MET	P08581	MET	Y1003	R1004L	1004	Missense	proximal	1	no	28.602	28.555	EPSD	COSMIC	27.257	Down-regulation
TK_Met_MET_Y	P08581	MET	P08581	MET	Y1230	Y1235D	1235	Missense	distal	5	no	30.919	32.810	EPSD;PhosphoSitePlus	COSMIC	27.257	Up-regulation
TK_Met_MET_Y	P08581	MET	P08581	MET	Y1230	Y1230S	1230	Missense	central	0	yes	30.919	0.000	EPSD;PhosphoSitePlus	COSMIC	27.257	Loss
TK_Met_MET_Y	P08581	MET	P08581	MET	Y1230	D1228N	1228	Missense	proximal	-2	no	30.919	24.896	EPSD;PhosphoSitePlus	COSMIC	27.257	Loss
TK_Met_MET_Y	P08581	MET	P08581	MET	Y1230	G1224D	1224	Missense	distal	-6	no	30.919	30.316	EPSD;PhosphoSitePlus	COSMIC	27.257	Down-regulation
TK_Met_MET_Y	P08581	MET	P08581	MET	Y1230	G1224A	1224	Missense	distal	-6	no	30.919	30.370	EPSD;PhosphoSitePlus	COSMIC	27.257	Down-regulation
TK_Met_MET_Y	P08581	MET	P08581	MET	Y1230	M1229L	1229	Missense	proximal	-1	no	30.919	28.079	EPSD;PhosphoSitePlus	COSMIC	27.257	Down-regulation
TK_Met_MET_Y	P08581	MET	P08581	MET	Y1230	D1231N	1231	Missense	proximal	1	no	30.919	30.475	EPSD;PhosphoSitePlus	COSMIC	27.257	Down-regulation
TK_Met_MET_Y	P08581	MET	P08581	MET	Y1230	D1228V	1228	Missense	proximal	-2	no	30.919	22.525	EPSD;PhosphoSitePlus	COSMIC	27.257	Loss
TK_Met_MET_Y	P08581	MET	P08581	MET	Y1230	M1229V	1229	Missense	proximal	-1	no	30.919	29.311	EPSD;PhosphoSitePlus	COSMIC	27.257	Down-regulation
TK_Met_MET_Y	P08581	MET	P08581	MET	Y1234	Y1235D	1235	Missense	proximal	1	no	47.625	48.848	EPSD;PhosphoSitePlus	COSMIC	27.257	Up-regulation
TK_Met_MET_Y	P08581	MET	P08581	MET	Y1234	Y1230S	1230	Missense	distal	-4	no	47.625	51.781	EPSD;PhosphoSitePlus	COSMIC	27.257	Up-regulation
TK_Met_MET_Y	P08581	MET	P08581	MET	Y1234	D1228N	1228	Missense	distal	-6	no	47.625	47.944	EPSD;PhosphoSitePlus	COSMIC	27.257	Up-regulation
TK_Met_MET_Y	P08581	MET	P08581	MET	Y1234	M1229L	1229	Missense	distal	-5	no	47.625	45.850	EPSD;PhosphoSitePlus	COSMIC	27.257	Down-regulation
TK_Met_MET_Y	P08581	MET	P08581	MET	Y1234	D1231N	1231	Missense	distal	-3	no	47.625	39.866	EPSD;PhosphoSitePlus	COSMIC	27.257	Down-regulation
TK_Met_MET_Y	P08581	MET	P08581	MET	Y1234	D1228V	1228	Missense	distal	-6	no	47.625	47.999	EPSD;PhosphoSitePlus	COSMIC	27.257	Up-regulation
TK_Met_MET_Y	P08581	MET	P08581	MET	Y1234	H1238R	1238	Missense	distal	4	no	47.625	47.153	EPSD;PhosphoSitePlus	COSMIC	27.257	Down-regulation
TK_Met_MET_Y	P08581	MET	P08581	MET	Y1234	M1229V	1229	Missense	distal	-5	no	47.625	46.608	EPSD;PhosphoSitePlus	COSMIC	27.257	Down-regulation
TK_Met_MET_Y	P08581	MET	P08581	MET	Y1235	G1242D	1242	Missense	distal	7	no	51.951	52.304	EPSD;PhosphoSitePlus	COSMIC	27.257	Up-regulation
TK_Met_MET_Y	P08581	MET	P08581	MET	Y1235	G1242A	1242	Missense	distal	7	no	51.951	52.150	EPSD;PhosphoSitePlus	COSMIC	27.257	Up-regulation
TK_Met_MET_Y	P08581	MET	P08581	MET	Y1235	Y1235D	1235	Missense	central	0	yes	51.951	0.000	EPSD;PhosphoSitePlus	COSMIC	27.257	Loss
TK_Met_MET_Y	P08581	MET	P08581	MET	Y1235	Y1230S	1230	Missense	distal	-5	no	51.951	53.767	EPSD;PhosphoSitePlus	COSMIC	27.257	Up-regulation
TK_Met_MET_Y	P08581	MET	P08581	MET	Y1235	D1228N	1228	Missense	distal	-7	no	51.951	50.956	EPSD;PhosphoSitePlus	COSMIC	27.257	Down-regulation
TK_Met_MET_Y	P08581	MET	P08581	MET	Y1235	M1229L	1229	Missense	distal	-6	no	51.951	52.532	EPSD;PhosphoSitePlus	COSMIC	27.257	Up-regulation
TK_Met_MET_Y	P08581	MET	P08581	MET	Y1235	D1231N	1231	Missense	distal	-4	no	51.951	49.596	EPSD;PhosphoSitePlus	COSMIC	27.257	Down-regulation
TK_Met_MET_Y	P08581	MET	P08581	MET	Y1235	G1242C	1242	Missense	distal	7	no	51.951	51.885	EPSD;PhosphoSitePlus	COSMIC	27.257	Down-regulation
TK_Met_MET_Y	P08581	MET	P08581	MET	Y1235	D1228V	1228	Missense	distal	-7	no	51.951	50.013	EPSD;PhosphoSitePlus	COSMIC	27.257	Down-regulation
TK_Met_MET_Y	P08581	MET	P08581	MET	Y1235	H1238R	1238	Missense	distal	3	no	51.951	47.076	EPSD;PhosphoSitePlus	COSMIC	27.257	Down-regulation
TK_Met_MET_Y	P08581	MET	P08581	MET	Y1235	M1229V	1229	Missense	distal	-6	no	51.951	52.287	EPSD;PhosphoSitePlus	COSMIC	27.257	Up-regulation
TK_Met_MET_Y	P08581	MET	P08581	MET	Y1313	E1306K	1306	Missense	distal	-7	no	31.893	30.919	EPSD	COSMIC	27.257	Down-regulation
TK_Met_MET_Y	P08581	MET	P08581	MET	Y1313	W1320C	1320	Missense	distal	7	no	31.893	31.799	EPSD	COSMIC	27.257	Down-regulation
TK_Met_MET_Y	P08581	MET	P08581	MET	Y1313	C1308F	1308	Missense	distal	-5	no	31.893	31.413	EPSD	COSMIC	27.257	Down-regulation
TK_Met_MET_Y	P08581	MET	P08581	MET	Y1349	H1348N	1348	Missense	proximal	-1	no	45.667	46.836	EPSD;PhosphoSitePlus	COSMIC	27.257	Up-regulation
TK_Met_MET_Y	P08581	MET	P08581	MET	Y1349	A1354P	1354	Missense	distal	5	no	45.667	47.371	EPSD;PhosphoSitePlus	COSMIC	27.257	Up-regulation
TK_Met_MET_Y	P08581	MET	P08581	MET	Y1349	G1346W	1346	Missense	distal	-3	no	45.667	43.283	EPSD;PhosphoSitePlus	COSMIC	27.257	Down-regulation
TK_Met_MET_Y	P08581	MET	P08581	MET	Y1349	I1345T	1345	Missense	distal	-4	no	45.667	49.166	EPSD;PhosphoSitePlus	COSMIC	27.257	Up-regulation
TK_Met_MET_Y	P08581	MET	P08581	MET	Y1356	K1360E	1360	Missense	distal	4	no	49.989	50.224	PhosphoSitePlus;EPSD	COSMIC	27.257	Up-regulation
TK_Met_MET_Y	P08581	MET	P08581	MET	Y1356	A1354P	1354	Missense	proximal	-2	no	49.989	47.861	PhosphoSitePlus;EPSD	COSMIC	27.257	Down-regulation
TK_Met_MET_Y	P08581	MET	P08581	MET	Y1356	A1363T	1363	Missense	distal	7	no	49.989	50.012	PhosphoSitePlus;EPSD	COSMIC	27.257	Up-regulation
TK_Met_MET_Y	P08581	MET	P08581	MET	Y1356	V1359I	1359	Missense	distal	3	no	49.989	40.779	PhosphoSitePlus;EPSD	COSMIC	27.257	Down-regulation
TK_Met_MET_Y	Q04912	MST1R	P08581	MET	Y1238	V1241D	1241	Missense	distal	3	no	39.124	30.539	EPSD;PhosphoSitePlus	COSMIC	27.257	Down-regulation
TK_Met_MET_Y	Q04912	MST1R	P08581	MET	Y1238	Y1238H	1238	Missense	central	0	yes	39.124	0.000	EPSD;PhosphoSitePlus	COSMIC	27.257	Loss
TK_Met_MET_Y	Q04912	MST1R	P08581	MET	Y1238	R1231S	1231	Missense	distal	-7	no	39.124	40.617	EPSD;PhosphoSitePlus	COSMIC	27.257	Up-regulation
TK_Met_MET_Y	Q04912	MST1R	P08581	MET	Y1238	Y1238C	1238	Missense	central	0	yes	39.124	0.000	EPSD;PhosphoSitePlus	COSMIC	27.257	Loss
TK_Met_MET_Y	Q04912	MST1R	P08581	MET	Y1238	R1236S	1236	Missense	proximal	-2	no	39.124	47.418	EPSD;PhosphoSitePlus	COSMIC	27.257	Up-regulation
TK_Met_MET_Y	Q04912	MST1R	P08581	MET	Y1238	D1232N	1232	Missense	distal	-6	no	39.124	39.443	EPSD;PhosphoSitePlus	COSMIC	27.257	Up-regulation
TK_Met_MET_Y	Q04912	MST1R	P08581	MET	Y1238	I1233M	1233	Missense	distal	-5	no	39.124	40.214	EPSD;PhosphoSitePlus	COSMIC	27.257	Up-regulation
TK_Met_MET_Y	Q04912	MST1R	P08581	MET	Y1238	R1236M	1236	Missense	proximal	-2	no	39.124	42.594	EPSD;PhosphoSitePlus	COSMIC	27.257	Up-regulation
TK_Met_MET_Y	Q04912	MST1R	P08581	MET	Y1238	R1245S	1245	Missense	distal	7	no	39.124	39.428	EPSD;PhosphoSitePlus	COSMIC	27.257	Up-regulation
TK_Met_MET_Y	Q04912	MST1R	P08581	MET	Y1239	V1241D	1241	Missense	proximal	2	no	39.326	39.579	EPSD;PhosphoSitePlus	COSMIC	27.257	Up-regulation
TK_Met_MET_Y	Q04912	MST1R	P08581	MET	Y1239	Y1238H	1238	Missense	proximal	-1	no	39.326	39.813	EPSD;PhosphoSitePlus	COSMIC	27.257	Up-regulation
TK_Met_MET_Y	Q04912	MST1R	P08581	MET	Y1239	Y1238C	1238	Missense	proximal	-1	no	39.326	38.718	EPSD;PhosphoSitePlus	COSMIC	27.257	Down-regulation
TK_Met_MET_Y	Q04912	MST1R	P08581	MET	Y1239	R1236S	1236	Missense	distal	-3	no	39.326	46.671	EPSD;PhosphoSitePlus	COSMIC	27.257	Up-regulation
TK_Met_MET_Y	Q04912	MST1R	P08581	MET	Y1239	D1232N	1232	Missense	distal	-7	no	39.326	38.332	EPSD;PhosphoSitePlus	COSMIC	27.257	Down-regulation
TK_Met_MET_Y	Q04912	MST1R	P08581	MET	Y1239	I1233M	1233	Missense	distal	-6	no	39.326	38.833	EPSD;PhosphoSitePlus	COSMIC	27.257	Down-regulation
TK_Met_MET_Y	Q04912	MST1R	P08581	MET	Y1239	R1236M	1236	Missense	distal	-3	no	39.326	38.535	EPSD;PhosphoSitePlus	COSMIC	27.257	Down-regulation
TK_Met_MET_Y	Q04912	MST1R	P08581	MET	Y1239	R1245S	1245	Missense	distal	6	no	39.326	41.770	EPSD;PhosphoSitePlus	COSMIC	27.257	Up-regulation
TK_Met_MET_Y	Q04912	MST1R	P08581	MET	Y1353	Y1353H	1353	Missense	central	0	yes	46.732	0.000	PhosphoSitePlus;EPSD	COSMIC	27.257	Loss
TK_Met_MET_Y	Q04912	MST1R	P08581	MET	Y1360	P1365H	1365	Missense	distal	5	no	30.446	27.957	EPSD;PhosphoSitePlus	COSMIC	27.257	Down-regulation
TK_Met_MET_Y	Q04912	MST1R	P08581	MET	Y1360	Y1353H	1353	Missense	distal	-7	no	30.446	30.784	EPSD;PhosphoSitePlus	COSMIC	27.257	Up-regulation
TK_Met_MET_Y	Q04912	MST1R	P08581	MET	Y1360	G1364S	1364	Missense	distal	4	no	30.446	36.776	EPSD;PhosphoSitePlus	COSMIC	27.257	Up-regulation
TK_Met_MET_Y	Q04912	MST1R	P08581	MET	Y1360	G1364C	1364	Missense	distal	4	no	30.446	28.608	EPSD;PhosphoSitePlus	COSMIC	27.257	Down-regulation
TK_Met_MET_Y	P35568	IRS1	P08581	MET	Y431	P435L	435	Missense	distal	4	no	45.192	37.917	EPSD	COSMIC	27.257	Down-regulation
TK_Met_MET_Y	P35568	IRS1	P08581	MET	Y431	S434G	434	Missense	distal	3	no	45.192	35.875	EPSD	COSMIC	27.257	Down-regulation
TK_Met_MET_Y	P35568	IRS1	P08581	MET	Y431	G424C	424	Missense	distal	-7	no	45.192	44.813	EPSD	COSMIC	27.257	Down-regulation
TK_Met_MET_Y	P35568	IRS1	P08581	MET	Y431	P435F	435	Missense	distal	4	no	45.192	37.788	EPSD	COSMIC	27.257	Down-regulation
TK_Met_MET_Y	P35568	IRS1	P08581	MET	Y551	M554T	554	Missense	distal	3	no	40.727	33.674	EPSD	COSMIC	27.257	Down-regulation
TK_Met_MET_Y	P35568	IRS1	P08581	MET	Y551	Y558C	558	Missense	distal	7	no	40.727	40.667	EPSD	COSMIC	27.257	Down-regulation
TK_Met_MET_Y	P35568	IRS1	P08581	MET	Y551	Y551C	551	Missense	central	0	yes	40.727	0.000	EPSD	COSMIC	27.257	Loss
TK_Met_MET_Y	P35568	IRS1	P08581	MET	Y582	P578S	578	Missense	distal	-4	no	26.809	28.062	EPSD	COSMIC	27.257	Gain
TK_Met_MET_Y	P35568	IRS1	P08581	MET	Y612	P614A	614	Missense	proximal	2	no	72.978	72.484	PhosphoSitePlus;EPSD	COSMIC;CCLE	27.257	Down-regulation
TK_Met_MET_Y	P35568	IRS1	P08581	MET	Y632	G628D	628	Missense	distal	-4	no	46.790	51.619	EPSD	COSMIC	27.257	Up-regulation
TK_Met_MET_Y	P35568	IRS1	P08581	MET	Y632	R626Q	626	Missense	distal	-6	no	46.790	46.689	EPSD	COSMIC	27.257	Down-regulation
TK_Met_MET_Y	P35568	IRS1	P08581	MET	Y632	G630E	630	Missense	proximal	-2	no	46.790	56.658	EPSD	COSMIC	27.257	Up-regulation
TK_Met_MET_Y	P35568	IRS1	P08581	MET	Y662	G661D	661	Missense	proximal	-1	no	62.811	66.055	EPSD	COSMIC	27.257	Up-regulation
TK_Met_MET_Y	P35568	IRS1	P08581	MET	Y662	G669S	669	Missense	distal	7	no	62.811	63.204	EPSD	COSMIC	27.257	Up-regulation
TK_Met_MET_Y	P35568	IRS1	P08581	MET	Y662	M664I	664	Missense	proximal	2	no	62.811	61.208	EPSD	COSMIC	27.257	Down-regulation
TK_Met_MET_Y	P35568	IRS1	P08581	MET	Y662	V657L	657	Missense	distal	-5	no	62.811	62.053	EPSD	COSMIC	27.257	Down-regulation
TK_Met_MET_Y	P35568	IRS1	P08581	MET	Y662	Q655H	655	Missense	distal	-7	no	62.811	62.680	EPSD	COSMIC;GDSC;CCLE	27.257	Down-regulation
TK_Met_MET_Y	P35568	IRS1	P08581	MET	Y695	G696A	696	Missense	proximal	1	no	33.992	36.087	EPSD	COSMIC;GDSC;CCLE	27.257	Up-regulation
TK_Met_MET_Y	P35568	IRS1	P08581	MET	Y695	A688T	688	Missense	distal	-7	no	33.992	33.593	EPSD	COSMIC	27.257	Down-regulation
TK_Met_MET_Y	P35568	IRS1	P08581	MET	Y695	Y695F	695	Missense	central	0	yes	33.992	0.000	EPSD	COSMIC;GDSC	27.257	Loss
TK_Met_MET_Y	P35568	IRS1	P08581	MET	Y732	D731G	731	Missense	proximal	-1	no	36.487	33.243	EPSD	COSMIC	27.257	Down-regulation
TK_Met_MET_Y	P35568	IRS1	P08581	MET	Y732	V738G	738	Missense	distal	6	no	36.487	37.252	EPSD	COSMIC	27.257	Up-regulation
TK_Met_MET_Y	P35568	IRS1	P08581	MET	Y732	G739E	739	Missense	distal	7	no	36.487	36.794	EPSD	COSMIC	27.257	Up-regulation
TK_Met_MET_Y	P35568	IRS1	P08581	MET	Y732	N734I	734	Missense	proximal	2	no	36.487	35.510	EPSD	COSMIC	27.257	Down-regulation
TK_Met_MET_Y	P35568	IRS1	P08581	MET	Y732	N734K	734	Missense	proximal	2	no	36.487	36.358	EPSD	COSMIC	27.257	Down-regulation
TK_Met_MET_Y	P35568	IRS1	P08581	MET	Y750	Q757K	757	Missense	distal	7	no	54.834	54.895	EPSD	COSMIC	27.257	Up-regulation
TK_Met_MET_Y	P35568	IRS1	P08581	MET	Y750	P753L	753	Missense	distal	3	no	54.834	45.501	EPSD	COSMIC	27.257	Down-regulation
TK_Met_MET_Y	P35568	IRS1	P08581	MET	Y751	Q757K	757	Missense	distal	6	no	26.975	27.516	EPSD	COSMIC	27.257	Gain
TK_Met_MET_Y	P35568	IRS1	P08581	MET	Y764	S763A	763	Missense	proximal	-1	no	31.418	29.993	EPSD	COSMIC	27.257	Down-regulation
TK_Met_MET_Y	P35568	IRS1	P08581	MET	Y764	Q757K	757	Missense	distal	-7	no	31.418	31.767	EPSD	COSMIC	27.257	Up-regulation
TK_Met_MET_Y	P35568	IRS1	P08581	MET	Y764	S766T	766	Missense	proximal	2	no	31.418	30.853	EPSD	COSMIC	27.257	Down-regulation
TK_Met_MET_Y	P35568	IRS1	P08581	MET	Y765	S763A	763	Missense	proximal	-2	no	29.558	28.108	EPSD	COSMIC	27.257	Down-regulation
TK_Met_MET_Y	P35568	IRS1	P08581	MET	Y765	S766T	766	Missense	proximal	1	no	29.558	29.160	EPSD	COSMIC	27.257	Down-regulation
TK_Met_MET_Y	P35568	IRS1	P08581	MET	Y941	K943Q	943	Missense	proximal	2	no	35.701	35.394	EPSD	COSMIC	27.257	Down-regulation
TK_Met_MET_Y	P35568	IRS1	P08581	MET	Y941	T936I	936	Missense	distal	-5	no	35.701	34.695	EPSD	COSMIC	27.257	Down-regulation
TK_Met_MET_Y	P35568	IRS1	P08581	MET	Y941	L946P	946	Missense	distal	5	no	35.701	39.495	EPSD	COSMIC	27.257	Up-regulation
TK_Met_MET_Y	P35568	IRS1	P08581	MET	Y989	P983S	983	Missense	distal	-6	no	48.647	48.695	EPSD	COSMIC	27.257	Up-regulation
TK_Met_MET_Y	P35568	IRS1	P08581	MET	Y989	S985N	985	Missense	distal	-4	no	48.647	46.357	EPSD	COSMIC	27.257	Down-regulation
TK_Met_MET_Y	P35568	IRS1	P08581	MET	Y989	M992K	992	Missense	distal	3	no	48.647	40.377	EPSD	COSMIC	27.257	Down-regulation
TK_Met_MET_Y	P35568	IRS1	P08581	MET	Y1001	R998C	998	Missense	distal	-3	no	48.998	43.442	EPSD	COSMIC;GDSC;CCLE	27.257	Down-regulation
TK_Met_MET_Y	P35568	IRS1	P08581	MET	Y1001	D1003H	1003	Missense	proximal	2	no	48.998	48.634	EPSD	COSMIC	27.257	Down-regulation
TK_Met_MET_Y	P35568	IRS1	P08581	MET	Y1001	P997S	997	Missense	distal	-4	no	48.998	50.251	EPSD	COSMIC	27.257	Up-regulation
TK_Met_MET_Y	P35568	IRS1	P08581	MET	Y1012	S1011I	1011	Missense	proximal	-1	no	54.832	50.751	EPSD	COSMIC	27.257	Down-regulation
TK_Met_MET_Y	P35568	IRS1	P08581	MET	Y1012	P1009S	1009	Missense	distal	-3	no	54.832	63.386	EPSD	COSMIC	27.257	Up-regulation
TK_Met_MET_Y	P35568	IRS1	P08581	MET	Y1012	D1014G	1014	Missense	proximal	2	no	54.832	53.648	EPSD	COSMIC	27.257	Down-regulation
TK_Met_MET_Y	Q05397	PTK2	P08581	MET	Y5	A3T	3	Missense	proximal	-2	no	33.030	27.842	EPSD;PhosphoSitePlus	COSMIC	27.257	Down-regulation
TK_Met_MET_Y	Q05397	PTK2	P08581	MET	Y5	H12D	12	Missense	distal	7	no	33.030	33.308	EPSD;PhosphoSitePlus	COSMIC	27.257	Up-regulation
TK_Met_MET_Y	Q05397	PTK2	P08581	MET	Y5	A4T	4	Missense	proximal	-1	no	33.030	33.252	EPSD;PhosphoSitePlus	COSMIC	27.257	Up-regulation
TK_Met_MET_Y	Q05397	PTK2	P08581	MET	Y397	S390A	390	Missense	distal	-7	no	43.868	43.232	EPSD;PhosphoSitePlus	COSMIC	27.257	Down-regulation
TK_Met_MET_Y	Q05397	PTK2	P08581	MET	Y397	D402V	402	Missense	distal	5	no	43.868	43.379	EPSD;PhosphoSitePlus	COSMIC	27.257	Down-regulation
TK_Met_MET_Y	Q05397	PTK2	P08581	MET	Y397	E404A	404	Missense	distal	7	no	43.868	43.762	EPSD;PhosphoSitePlus	COSMIC	27.257	Down-regulation
TK_Met_MET_Y	Q05397	PTK2	P08581	MET	Y397	V391A	391	Missense	distal	-6	no	43.868	43.549	EPSD;PhosphoSitePlus	COSMIC	27.257	Down-regulation
TK_Met_MET_Y	Q05397	PTK2	P08581	MET	Y407	D402V	402	Missense	distal	-5	no	72.144	70.117	EPSD;PhosphoSitePlus	COSMIC	27.257	Down-regulation
TK_Met_MET_Y	Q05397	PTK2	P08581	MET	Y407	D405G	405	Missense	proximal	-2	no	72.144	62.466	EPSD;PhosphoSitePlus	COSMIC	27.257	Down-regulation
TK_Met_MET_Y	Q05397	PTK2	P08581	MET	Y407	R413S	413	Missense	distal	6	no	72.144	74.587	EPSD;PhosphoSitePlus	COSMIC	27.257	Up-regulation
TK_Met_MET_Y	Q05397	PTK2	P08581	MET	Y407	E404A	404	Missense	distal	-3	no	72.144	68.377	EPSD;PhosphoSitePlus	COSMIC	27.257	Down-regulation
TK_Met_MET_Y	Q05397	PTK2	P08581	MET	Y576	R569L	569	Missense	distal	-7	no	57.941	56.714	EPSD;PhosphoSitePlus	COSMIC	27.257	Down-regulation
TK_Met_MET_Y	Q05397	PTK2	P08581	MET	Y576	A579V	579	Missense	distal	3	no	57.941	62.589	EPSD;PhosphoSitePlus	COSMIC	27.257	Up-regulation
TK_Met_MET_Y	Q05397	PTK2	P08581	MET	Y577	A579V	579	Missense	proximal	2	no	45.872	45.416	EPSD;PhosphoSitePlus	COSMIC	27.257	Down-regulation
TK_Met_MET_Y	Q05397	PTK2	P08581	MET	Y720	S722I	722	Missense	proximal	2	no	38.240	36.594	EPSD	COSMIC	27.257	Down-regulation
TK_Met_MET_Y	Q05397	PTK2	P08581	MET	Y761	A765T	765	Missense	distal	4	no	32.646	35.367	EPSD	COSMIC	27.257	Up-regulation
TK_Met_MET_Y	Q05397	PTK2	P08581	MET	Y761	L768F	768	Missense	distal	7	no	32.646	32.668	EPSD	COSMIC	27.257	Up-regulation
TK_Met_MET_Y	Q05397	PTK2	P08581	MET	Y761	S766I	766	Missense	distal	5	no	32.646	27.815	EPSD	COSMIC	27.257	Down-regulation
TK_Met_MET_Y	Q05397	PTK2	P08581	MET	Y761	P762L	762	Missense	proximal	1	no	32.646	29.456	EPSD	COSMIC	27.257	Down-regulation
TK_Met_MET_Y	Q05397	PTK2	P08581	MET	Y898	E900V	900	Missense	proximal	2	no	44.742	44.085	EPSD	COSMIC	27.257	Down-regulation
TK_Met_MET_Y	Q05397	PTK2	P08581	MET	Y925	G930C	930	Missense	distal	5	no	56.927	56.666	PhosphoSitePlus;EPSD	COSMIC	27.257	Down-regulation
TK_Met_MET_Y	Q05397	PTK2	P08581	MET	Y925	D918G	918	Missense	distal	-7	no	56.927	55.263	PhosphoSitePlus;EPSD	COSMIC	27.257	Down-regulation
TK_Met_MET_Y	Q05397	PTK2	P08581	MET	Y925	E926K	926	Missense	proximal	1	no	56.927	56.426	PhosphoSitePlus;EPSD	COSMIC	27.257	Down-regulation
TK_Met_MET_Y	Q05397	PTK2	P08581	MET	Y925	Y925C	925	Missense	central	0	yes	56.927	0.000	PhosphoSitePlus;EPSD	COSMIC	27.257	Loss
TK_Met_MET_Y	Q05397	PTK2	P08581	MET	Y925	R919L	919	Missense	distal	-6	no	56.927	57.106	PhosphoSitePlus;EPSD	COSMIC	27.257	Up-regulation
TK_Met_MET_Y	Q05397	PTK2	P08581	MET	Y925	R919Q	919	Missense	distal	-6	no	56.927	56.826	PhosphoSitePlus;EPSD	COSMIC	27.257	Down-regulation
TK_Met_MET_Y	P06213	INSR	P08581	MET	Y1149	A1152T	1152	Missense	distal	3	no	36.816	36.596	EPSD	COSMIC	27.257	Down-regulation
TK_Met_MET_Y	P06213	INSR	P08581	MET	Y1189	Y1190C	1190	Missense	proximal	1	no	27.191	27.448	EPSD	COSMIC	27.257	Gain
TK_Met_MET_Y	P06213	INSR	P08581	MET	Y1189	R1191W	1191	Missense	proximal	2	no	27.191	27.352	EPSD	COSMIC	27.257	Gain
TK_Met_MET_Y	P06213	INSR	P08581	MET	Y1190	Y1190C	1190	Missense	central	0	yes	31.563	0.000	EPSD	COSMIC	27.257	Loss
TK_Met_MET_Y	P06213	INSR	P08581	MET	Y1190	R1191W	1191	Missense	proximal	1	no	31.563	32.186	EPSD	COSMIC	27.257	Up-regulation
TK_Met_MET_Y	P06213	INSR	P08581	MET	Y1361	G1366R	1366	Missense	distal	5	no	27.046	27.604	EPSD	COSMIC;CCLE	27.257	Gain
TK_Met_MET_Y	P06213	INSR	P08581	MET	Y1361	P1360S	1360	Missense	proximal	-1	no	27.046	27.909	EPSD	COSMIC	27.257	Gain
CMGC_DYRK_DYRK1_DYRK1A_ST	P10636	MAPT	Q13627	DYRK1A	S64	E62K	62	Missense	proximal	-2	no	41.642	41.398	EPSD	COSMIC	34.163	Down-regulation
CMGC_DYRK_DYRK1_DYRK1A_ST	P10636	MAPT	Q13627	DYRK1A	T69	E62K	62	Missense	distal	-7	no	44.531	44.771	EPSD	COSMIC	34.163	Up-regulation
CMGC_DYRK_DYRK1_DYRK1A_ST	P10636	MAPT	Q13627	DYRK1A	T111	I108V	108	Missense	distal	-3	no	49.672	51.562	EPSD	COSMIC	34.163	Up-regulation
CMGC_DYRK_DYRK1_DYRK1A_ST	P10636	MAPT	Q13627	DYRK1A	T111	G107R	107	Missense	distal	-4	no	49.672	49.708	EPSD	COSMIC	34.163	Up-regulation
CMGC_DYRK_DYRK1_DYRK1A_ST	P10636	MAPT	Q13627	DYRK1A	T167	P160Q	160	Missense	distal	-7	no	34.037	34.450	EPSD	COSMIC	34.163	Gain
CMGC_DYRK_DYRK1_DYRK1A_ST	P10636	MAPT	Q13627	DYRK1A	T167	A166V	166	Missense	proximal	-1	no	34.037	34.581	EPSD	COSMIC;CCLE	34.163	Gain
CMGC_DYRK_DYRK1_DYRK1A_ST	P10636	MAPT	Q13627	DYRK1A	S171	P175S	175	Missense	distal	4	no	40.913	41.110	EPSD	COSMIC	34.163	Up-regulation
CMGC_DYRK_DYRK1_DYRK1A_ST	P10636	MAPT	Q13627	DYRK1A	S171	A166V	166	Missense	distal	-5	no	40.913	41.344	EPSD	COSMIC;CCLE	34.163	Up-regulation
CMGC_DYRK_DYRK1_DYRK1A_ST	P10636	MAPT	Q13627	DYRK1A	S171	E176G	176	Missense	distal	5	no	40.913	40.623	EPSD	COSMIC	34.163	Down-regulation
CMGC_DYRK_DYRK1_DYRK1A_ST	P10636	MAPT	Q13627	DYRK1A	S171	D177G	177	Missense	distal	6	no	40.913	40.766	EPSD	COSMIC	34.163	Down-regulation
CMGC_DYRK_DYRK1_DYRK1A_ST	P10636	MAPT	Q13627	DYRK1A	S171	E165K	165	Missense	distal	-6	no	40.913	40.376	EPSD	COSMIC	34.163	Down-regulation
CMGC_DYRK_DYRK1_DYRK1A_ST	P10636	MAPT	Q13627	DYRK1A	S171	G172V	172	Missense	proximal	1	no	40.913	45.742	EPSD	COSMIC	34.163	Up-regulation
CMGC_DYRK_DYRK1_DYRK1A_ST	P10636	MAPT	Q13627	DYRK1A	T173	P175S	175	Missense	proximal	2	no	40.645	40.544	EPSD	COSMIC	34.163	Down-regulation
CMGC_DYRK_DYRK1_DYRK1A_ST	P10636	MAPT	Q13627	DYRK1A	T173	A166V	166	Missense	distal	-7	no	40.645	41.461	EPSD	COSMIC;CCLE	34.163	Up-regulation
CMGC_DYRK_DYRK1_DYRK1A_ST	P10636	MAPT	Q13627	DYRK1A	T173	E176G	176	Missense	distal	3	no	40.645	40.693	EPSD	COSMIC	34.163	Up-regulation
CMGC_DYRK_DYRK1_DYRK1A_ST	P10636	MAPT	Q13627	DYRK1A	T173	D177G	177	Missense	distal	4	no	40.645	39.238	EPSD	COSMIC	34.163	Down-regulation
CMGC_DYRK_DYRK1_DYRK1A_ST	P10636	MAPT	Q13627	DYRK1A	T173	G172V	172	Missense	proximal	-1	no	40.645	40.849	EPSD	COSMIC	34.163	Up-regulation
CMGC_DYRK_DYRK1_DYRK1A_ST	P10636	MAPT	Q13627	DYRK1A	S214	E210Q	210	Missense	distal	-4	no	45.770	45.768	EPSD	COSMIC	34.163	Down-regulation
CMGC_DYRK_DYRK1_DYRK1A_ST	P10636	MAPT	Q13627	DYRK1A	S214	G207E	207	Missense	distal	-7	no	45.770	45.520	EPSD	COSMIC	34.163	Down-regulation
CMGC_DYRK_DYRK1_DYRK1A_ST	P10636	MAPT	Q13627	DYRK1A	S228	S227N	227	Missense	proximal	-1	no	47.818	48.677	EPSD	COSMIC	34.163	Up-regulation
CMGC_DYRK_DYRK1_DYRK1A_ST	P10636	MAPT	Q13627	DYRK1A	S228	S227I	227	Missense	proximal	-1	no	47.818	48.674	EPSD	COSMIC	34.163	Up-regulation
CMGC_DYRK_DYRK1_DYRK1A_ST	P10636	MAPT	Q13627	DYRK1A	S228	E226K	226	Missense	proximal	-2	no	47.818	47.573	EPSD	COSMIC	34.163	Down-regulation
CMGC_DYRK_DYRK1_DYRK1A_ST	P10636	MAPT	Q13627	DYRK1A	S228	Q230R	230	Missense	proximal	2	no	47.818	48.007	EPSD	COSMIC	34.163	Up-regulation
CMGC_DYRK_DYRK1_DYRK1A_ST	P10636	MAPT	Q13627	DYRK1A	S228	P233S	233	Missense	distal	5	no	47.818	47.879	EPSD	COSMIC	34.163	Up-regulation
CMGC_DYRK_DYRK1_DYRK1A_ST	P10636	MAPT	Q13627	DYRK1A	S228	D225E	225	Missense	distal	-3	no	47.818	44.835	EPSD	COSMIC	34.163	Down-regulation
CMGC_DYRK_DYRK1_DYRK1A_ST	P10636	MAPT	Q13627	DYRK1A	S228	S227G	227	Missense	proximal	-1	no	47.818	48.390	EPSD	COSMIC	34.163	Up-regulation
CMGC_DYRK_DYRK1_DYRK1A_ST	P10636	MAPT	Q13627	DYRK1A	S228	S235L	235	Missense	distal	7	no	47.818	49.972	EPSD	COSMIC	34.163	Up-regulation
CMGC_DYRK_DYRK1_DYRK1A_ST	P10636	MAPT	Q13627	DYRK1A	S232	A237T	237	Missense	distal	5	no	33.362	35.224	EPSD	COSMIC	34.163	Gain
CMGC_DYRK_DYRK1_DYRK1A_ST	P10636	MAPT	Q13627	DYRK1A	S232	Q230R	230	Missense	proximal	-2	no	33.362	37.541	EPSD	COSMIC	34.163	Gain
CMGC_DYRK_DYRK1_DYRK1A_ST	P10636	MAPT	Q13627	DYRK1A	S235	A237T	237	Missense	proximal	2	no	46.531	45.971	EPSD	COSMIC	34.163	Down-regulation
CMGC_DYRK_DYRK1_DYRK1A_ST	P10636	MAPT	Q13627	DYRK1A	S235	A240S	240	Missense	distal	5	no	46.531	46.910	EPSD	COSMIC	34.163	Up-regulation
CMGC_DYRK_DYRK1_DYRK1A_ST	P10636	MAPT	Q13627	DYRK1A	S235	D242N	242	Missense	distal	7	no	46.531	47.620	EPSD	COSMIC	34.163	Up-regulation
CMGC_DYRK_DYRK1_DYRK1A_ST	P10636	MAPT	Q13627	DYRK1A	S235	Q230R	230	Missense	distal	-5	no	46.531	47.683	EPSD	COSMIC	34.163	Up-regulation
CMGC_DYRK_DYRK1_DYRK1A_ST	P10636	MAPT	Q13627	DYRK1A	S235	S238P	238	Missense	distal	3	no	46.531	46.010	EPSD	COSMIC	34.163	Down-regulation
CMGC_DYRK_DYRK1_DYRK1A_ST	P10636	MAPT	Q13627	DYRK1A	S235	P233S	233	Missense	proximal	-2	no	46.531	41.595	EPSD	COSMIC	34.163	Down-regulation
CMGC_DYRK_DYRK1_DYRK1A_ST	P10636	MAPT	Q13627	DYRK1A	S235	S238F	238	Missense	distal	3	no	46.531	45.974	EPSD	COSMIC	34.163	Down-regulation
CMGC_DYRK_DYRK1_DYRK1A_ST	P10636	MAPT	Q13627	DYRK1A	S235	S235L	235	Missense	central	0	yes	46.531	0.000	EPSD	COSMIC	34.163	Loss
CMGC_DYRK_DYRK1_DYRK1A_ST	P10636	MAPT	Q13627	DYRK1A	S238	A237T	237	Missense	proximal	-1	no	39.382	38.680	EPSD	COSMIC	34.163	Down-regulation
CMGC_DYRK_DYRK1_DYRK1A_ST	P10636	MAPT	Q13627	DYRK1A	S238	A240S	240	Missense	proximal	2	no	39.382	39.081	EPSD	COSMIC	34.163	Down-regulation
CMGC_DYRK_DYRK1_DYRK1A_ST	P10636	MAPT	Q13627	DYRK1A	S238	D242N	242	Missense	distal	4	no	39.382	39.047	EPSD	COSMIC	34.163	Down-regulation
CMGC_DYRK_DYRK1_DYRK1A_ST	P10636	MAPT	Q13627	DYRK1A	S238	R244W	244	Missense	distal	6	no	39.382	39.499	EPSD	COSMIC	34.163	Up-regulation
CMGC_DYRK_DYRK1_DYRK1A_ST	P10636	MAPT	Q13627	DYRK1A	S238	S238P	238	Missense	central	0	yes	39.382	0.000	EPSD	COSMIC	34.163	Loss
CMGC_DYRK_DYRK1_DYRK1A_ST	P10636	MAPT	Q13627	DYRK1A	S238	P233S	233	Missense	distal	-5	no	39.382	38.628	EPSD	COSMIC	34.163	Down-regulation
CMGC_DYRK_DYRK1_DYRK1A_ST	P10636	MAPT	Q13627	DYRK1A	S238	S238F	238	Missense	central	0	yes	39.382	0.000	EPSD	COSMIC	34.163	Loss
CMGC_DYRK_DYRK1_DYRK1A_ST	P10636	MAPT	Q13627	DYRK1A	S238	G243D	243	Missense	distal	5	no	39.382	37.794	EPSD	COSMIC	34.163	Down-regulation
CMGC_DYRK_DYRK1_DYRK1A_ST	P10636	MAPT	Q13627	DYRK1A	S238	S235L	235	Missense	distal	-3	no	39.382	34.617	EPSD	COSMIC	34.163	Down-regulation
CMGC_DYRK_DYRK1_DYRK1A_ST	P10636	MAPT	Q13627	DYRK1A	S411	L410F	410	Missense	proximal	-1	no	40.744	42.329	EPSD	COSMIC	34.163	Up-regulation
CMGC_DYRK_DYRK1_DYRK1A_ST	P10636	MAPT	Q13627	DYRK1A	S411	P412S	412	Missense	proximal	1	no	40.744	18.791	EPSD	COSMIC	34.163	Loss
CMGC_DYRK_DYRK1_DYRK1A_ST	P10636	MAPT	Q13627	DYRK1A	T416	L410F	410	Missense	distal	-6	no	53.618	52.754	EPSD	COSMIC	34.163	Down-regulation
CMGC_DYRK_DYRK1_DYRK1A_ST	P10636	MAPT	Q13627	DYRK1A	T416	P412S	412	Missense	distal	-4	no	53.618	53.619	EPSD	COSMIC	34.163	Up-regulation
CMGC_DYRK_DYRK1_DYRK1A_ST	P10636	MAPT	Q13627	DYRK1A	S438	S443Y	443	Missense	distal	5	no	58.880	54.237	EPSD	COSMIC	34.163	Down-regulation
CMGC_DYRK_DYRK1_DYRK1A_ST	P10636	MAPT	Q13627	DYRK1A	S447	R448Q	448	Missense	proximal	1	no	32.990	35.406	EPSD	COSMIC	34.163	Gain
CMGC_DYRK_DYRK1_DYRK1A_ST	P10636	MAPT	Q13627	DYRK1A	T492	R487K	487	Missense	distal	-5	no	45.275	44.111	EPSD	COSMIC	34.163	Down-regulation
CMGC_DYRK_DYRK1_DYRK1A_ST	P10636	MAPT	Q13627	DYRK1A	T492	K491R	491	Missense	proximal	-1	no	45.275	43.984	EPSD	COSMIC	34.163	Down-regulation
CMGC_DYRK_DYRK1_DYRK1A_ST	P10636	MAPT	Q13627	DYRK1A	T492	R487G	487	Missense	distal	-5	no	45.275	44.421	EPSD	COSMIC	34.163	Down-regulation
CMGC_DYRK_DYRK1_DYRK1A_ST	P10636	MAPT	Q13627	DYRK1A	T492	A495T	495	Missense	distal	3	no	45.275	44.844	EPSD	COSMIC	34.163	Down-regulation
CMGC_DYRK_DYRK1_DYRK1A_ST	P10636	MAPT	Q13627	DYRK1A	T492	P493L	493	Missense	proximal	1	no	45.275	2.944	EPSD	COSMIC	34.163	Loss
CMGC_DYRK_DYRK1_DYRK1A_ST	P10636	MAPT	Q13627	DYRK1A	T498	K491R	491	Missense	distal	-7	no	54.267	54.312	EPSD	COSMIC	34.163	Up-regulation
CMGC_DYRK_DYRK1_DYRK1A_ST	P10636	MAPT	Q13627	DYRK1A	T498	A495T	495	Missense	distal	-3	no	54.267	51.075	EPSD	COSMIC	34.163	Down-regulation
CMGC_DYRK_DYRK1_DYRK1A_ST	P10636	MAPT	Q13627	DYRK1A	T498	P493L	493	Missense	distal	-5	no	54.267	52.830	EPSD	COSMIC	34.163	Down-regulation
CMGC_DYRK_DYRK1_DYRK1A_ST	P10636	MAPT	Q13627	DYRK1A	S502	P506S	506	Missense	distal	4	no	38.732	38.928	EPSD	COSMIC	34.163	Up-regulation
CMGC_DYRK_DYRK1_DYRK1A_ST	P10636	MAPT	Q13627	DYRK1A	S502	A495T	495	Missense	distal	-7	no	38.732	38.133	EPSD	COSMIC	34.163	Down-regulation
CMGC_DYRK_DYRK1_DYRK1A_ST	P10636	MAPT	Q13627	DYRK1A	S502	G509V	509	Missense	distal	7	no	38.732	40.542	EPSD	COSMIC	34.163	Up-regulation
CMGC_DYRK_DYRK1_DYRK1A_ST	P10636	MAPT	Q13627	DYRK1A	S502	P506L	506	Missense	distal	4	no	38.732	40.779	EPSD	COSMIC	34.163	Up-regulation
CMGC_DYRK_DYRK1_DYRK1A_ST	P10636	MAPT	Q13627	DYRK1A	S508	P506S	506	Missense	proximal	-2	no	42.149	37.212	EPSD	COSMIC	34.163	Down-regulation
CMGC_DYRK_DYRK1_DYRK1A_ST	P10636	MAPT	Q13627	DYRK1A	S508	R511C	511	Missense	distal	3	no	42.149	42.047	EPSD	COSMIC;CCLE	34.163	Down-regulation
CMGC_DYRK_DYRK1_DYRK1A_ST	P10636	MAPT	Q13627	DYRK1A	S508	G509V	509	Missense	proximal	1	no	42.149	46.979	EPSD	COSMIC	34.163	Up-regulation
CMGC_DYRK_DYRK1_DYRK1A_ST	P10636	MAPT	Q13627	DYRK1A	S508	P506L	506	Missense	proximal	-2	no	42.149	28.421	EPSD	COSMIC	34.163	Loss
CMGC_DYRK_DYRK1_DYRK1A_ST	P10636	MAPT	Q13627	DYRK1A	S516	G521V	521	Missense	distal	5	no	52.447	47.568	EPSD	COSMIC	34.163	Down-regulation
CMGC_DYRK_DYRK1_DYRK1A_ST	P10636	MAPT	Q13627	DYRK1A	S516	G518V	518	Missense	proximal	2	no	52.447	51.118	EPSD	COSMIC	34.163	Down-regulation
CMGC_DYRK_DYRK1_DYRK1A_ST	P10636	MAPT	Q13627	DYRK1A	S516	R511C	511	Missense	distal	-5	no	52.447	50.446	EPSD	COSMIC;CCLE	34.163	Down-regulation
CMGC_DYRK_DYRK1_DYRK1A_ST	P10636	MAPT	Q13627	DYRK1A	S516	G509V	509	Missense	distal	-7	no	52.447	53.703	EPSD	COSMIC	34.163	Up-regulation
CMGC_DYRK_DYRK1_DYRK1A_ST	P10636	MAPT	Q13627	DYRK1A	S519	G521V	521	Missense	proximal	2	no	55.503	54.175	EPSD	COSMIC	34.163	Down-regulation
CMGC_DYRK_DYRK1_DYRK1A_ST	P10636	MAPT	Q13627	DYRK1A	S519	R526H	526	Missense	distal	7	no	55.503	58.527	EPSD	COSMIC	34.163	Up-regulation
CMGC_DYRK_DYRK1_DYRK1A_ST	P10636	MAPT	Q13627	DYRK1A	S519	G518V	518	Missense	proximal	-1	no	55.503	55.708	EPSD	COSMIC	34.163	Up-regulation
CMGC_DYRK_DYRK1_DYRK1A_ST	P10636	MAPT	Q13627	DYRK1A	T522	G521V	521	Missense	proximal	-1	no	56.470	56.674	EPSD	COSMIC	34.163	Up-regulation
CMGC_DYRK_DYRK1_DYRK1A_ST	P10636	MAPT	Q13627	DYRK1A	T522	R526H	526	Missense	distal	4	no	56.470	57.543	EPSD	COSMIC	34.163	Up-regulation
CMGC_DYRK_DYRK1_DYRK1A_ST	P10636	MAPT	Q13627	DYRK1A	T522	G518V	518	Missense	distal	-4	no	56.470	56.458	EPSD	COSMIC	34.163	Down-regulation
CMGC_DYRK_DYRK1_DYRK1A_ST	P10636	MAPT	Q13627	DYRK1A	T522	R528S	528	Missense	distal	6	no	56.470	56.531	EPSD	COSMIC	34.163	Up-regulation
CMGC_DYRK_DYRK1_DYRK1A_ST	P10636	MAPT	Q13627	DYRK1A	T529	R526H	526	Missense	distal	-3	no	56.569	41.237	EPSD	COSMIC	34.163	Down-regulation
CMGC_DYRK_DYRK1_DYRK1A_ST	P10636	MAPT	Q13627	DYRK1A	T529	R528S	528	Missense	proximal	-1	no	56.569	56.921	EPSD	COSMIC	34.163	Up-regulation
CMGC_DYRK_DYRK1_DYRK1A_ST	P10636	MAPT	Q13627	DYRK1A	T529	P530S	530	Missense	proximal	1	no	56.569	34.616	EPSD	COSMIC	34.163	Down-regulation
CMGC_DYRK_DYRK1_DYRK1A_ST	P10636	MAPT	Q13627	DYRK1A	T529	P536H	536	Missense	distal	7	no	56.569	58.117	EPSD	COSMIC	34.163	Up-regulation
CMGC_DYRK_DYRK1_DYRK1A_ST	P10636	MAPT	Q13627	DYRK1A	T529	P535Q	535	Missense	distal	6	no	56.569	56.524	EPSD	COSMIC	34.163	Down-regulation
CMGC_DYRK_DYRK1_DYRK1A_ST	P10636	MAPT	Q13627	DYRK1A	T534	R528S	528	Missense	distal	-6	no	52.389	52.675	EPSD	COSMIC	34.163	Up-regulation
CMGC_DYRK_DYRK1_DYRK1A_ST	P10636	MAPT	Q13627	DYRK1A	T534	P530S	530	Missense	distal	-4	no	52.389	52.391	EPSD	COSMIC	34.163	Up-regulation
CMGC_DYRK_DYRK1_DYRK1A_ST	P10636	MAPT	Q13627	DYRK1A	T534	P536H	536	Missense	proximal	2	no	52.389	51.667	EPSD	COSMIC	34.163	Down-regulation
CMGC_DYRK_DYRK1_DYRK1A_ST	P10636	MAPT	Q13627	DYRK1A	T534	P535Q	535	Missense	proximal	1	no	52.389	39.725	EPSD	COSMIC	34.163	Down-regulation
CMGC_DYRK_DYRK1_DYRK1A_ST	P10636	MAPT	Q13627	DYRK1A	T534	E539Q	539	Missense	distal	5	no	52.389	53.438	EPSD	COSMIC	34.163	Up-regulation
CMGC_DYRK_DYRK1_DYRK1A_ST	P10636	MAPT	Q13627	DYRK1A	T548	P550S	550	Missense	proximal	2	no	54.032	53.932	EPSD	COSMIC	34.163	Down-regulation
CMGC_DYRK_DYRK1_DYRK1A_ST	P10636	MAPT	Q13627	DYRK1A	T548	P553R	553	Missense	distal	5	no	54.032	55.667	EPSD	COSMIC	34.163	Up-regulation
CMGC_DYRK_DYRK1_DYRK1A_ST	P10636	MAPT	Q13627	DYRK1A	T548	P553L	553	Missense	distal	5	no	54.032	53.147	EPSD	COSMIC	34.163	Down-regulation
CMGC_DYRK_DYRK1_DYRK1A_ST	P10636	MAPT	Q13627	DYRK1A	T548	P549L	549	Missense	proximal	1	no	54.032	11.701	EPSD	COSMIC	34.163	Loss
CMGC_DYRK_DYRK1_DYRK1A_ST	P10636	MAPT	Q13627	DYRK1A	T548	S555F	555	Missense	distal	7	no	54.032	57.430	EPSD	COSMIC	34.163	Up-regulation
CMGC_DYRK_DYRK1_DYRK1A_ST	P10636	MAPT	Q13627	DYRK1A	T548	P553Q	553	Missense	distal	5	no	54.032	56.658	EPSD	COSMIC	34.163	Up-regulation
CMGC_DYRK_DYRK1_DYRK1A_ST	P10636	MAPT	Q13627	DYRK1A	S552	P550S	550	Missense	proximal	-2	no	58.137	53.201	EPSD	COSMIC	34.163	Down-regulation
CMGC_DYRK_DYRK1_DYRK1A_ST	P10636	MAPT	Q13627	DYRK1A	S552	R559C	559	Missense	distal	7	no	58.137	61.873	EPSD	COSMIC	34.163	Up-regulation
CMGC_DYRK_DYRK1_DYRK1A_ST	P10636	MAPT	Q13627	DYRK1A	S552	P553R	553	Missense	proximal	1	no	58.137	43.056	EPSD	COSMIC	34.163	Down-regulation
CMGC_DYRK_DYRK1_DYRK1A_ST	P10636	MAPT	Q13627	DYRK1A	S552	P553L	553	Missense	proximal	1	no	58.137	15.807	EPSD	COSMIC	34.163	Loss
CMGC_DYRK_DYRK1_DYRK1A_ST	P10636	MAPT	Q13627	DYRK1A	S552	P549L	549	Missense	distal	-3	no	58.137	56.144	EPSD	COSMIC	34.163	Down-regulation
CMGC_DYRK_DYRK1_DYRK1A_ST	P10636	MAPT	Q13627	DYRK1A	S552	S555F	555	Missense	distal	3	no	58.137	57.580	EPSD	COSMIC	34.163	Down-regulation
CMGC_DYRK_DYRK1_DYRK1A_ST	P10636	MAPT	Q13627	DYRK1A	S552	P553Q	553	Missense	proximal	1	no	58.137	45.473	EPSD	COSMIC	34.163	Down-regulation
CMGC_DYRK_DYRK1_DYRK1A_ST	P10636	MAPT	Q13627	DYRK1A	S558	V565M	565	Missense	distal	7	no	43.216	43.530	EPSD	COSMIC	34.163	Up-regulation
CMGC_DYRK_DYRK1_DYRK1A_ST	P10636	MAPT	Q13627	DYRK1A	S558	R559C	559	Missense	proximal	1	no	43.216	26.923	EPSD	COSMIC	34.163	Loss
CMGC_DYRK_DYRK1_DYRK1A_ST	P10636	MAPT	Q13627	DYRK1A	S558	P553R	553	Missense	distal	-5	no	43.216	43.691	EPSD	COSMIC	34.163	Up-regulation
CMGC_DYRK_DYRK1_DYRK1A_ST	P10636	MAPT	Q13627	DYRK1A	S558	P553L	553	Missense	distal	-5	no	43.216	41.779	EPSD	COSMIC	34.163	Down-regulation
CMGC_DYRK_DYRK1_DYRK1A_ST	P10636	MAPT	Q13627	DYRK1A	S558	S555F	555	Missense	distal	-3	no	43.216	24.043	EPSD	COSMIC	34.163	Loss
CMGC_DYRK_DYRK1_DYRK1A_ST	P10636	MAPT	Q13627	DYRK1A	S558	P553Q	553	Missense	distal	-5	no	43.216	42.540	EPSD	COSMIC	34.163	Down-regulation
CMGC_DYRK_DYRK1_DYRK1A_ST	P10636	MAPT	Q13627	DYRK1A	S637	S633N	633	Missense	distal	-4	no	35.842	35.846	EPSD	COSMIC	34.163	Up-regulation
CMGC_DYRK_DYRK1_DYRK1A_ST	P10636	MAPT	Q13627	DYRK1A	S637	S633I	633	Missense	distal	-4	no	35.842	35.798	EPSD	COSMIC	34.163	Down-regulation
CMGC_DYRK_DYRK1_DYRK1A_ST	P10636	MAPT	Q13627	DYRK1A	S669	S669L	669	Missense	central	0	yes	43.993	0.000	EPSD	COSMIC	34.163	Loss
CMGC_DYRK_DYRK1_DYRK1A_ST	P10636	MAPT	Q13627	DYRK1A	S669	R666K	666	Missense	distal	-3	no	43.993	36.148	EPSD	COSMIC	34.163	Down-regulation
CMGC_DYRK_DYRK1_DYRK1A_ST	P10636	MAPT	Q13627	DYRK1A	S669	D662G	662	Missense	distal	-7	no	43.993	43.160	EPSD	COSMIC	34.163	Down-regulation
CMGC_DYRK_DYRK1_DYRK1A_ST	P10636	MAPT	Q13627	DYRK1A	S669	S673F	673	Missense	distal	4	no	43.993	46.645	EPSD	COSMIC	34.163	Up-regulation
CMGC_DYRK_DYRK1_DYRK1A_ST	P10636	MAPT	Q13627	DYRK1A	S669	K670N	670	Missense	proximal	1	no	43.993	-8.489	EPSD	COSMIC	34.163	Loss
CMGC_DYRK_DYRK1_DYRK1A_ST	P10636	MAPT	Q13627	DYRK1A	S669	K664N	664	Missense	distal	-5	no	43.993	42.556	EPSD	COSMIC	34.163	Down-regulation
CMGC_DYRK_DYRK1_DYRK1A_ST	P10636	MAPT	Q13627	DYRK1A	S669	L674Q	674	Missense	distal	5	no	43.993	47.504	EPSD	COSMIC	34.163	Up-regulation
CMGC_DYRK_DYRK1_DYRK1A_ST	P10636	MAPT	Q13627	DYRK1A	T694	R696H	696	Missense	proximal	2	no	34.703	33.582	EPSD	COSMIC	34.163	Loss
CMGC_DYRK_DYRK1_DYRK1A_ST	P10636	MAPT	Q13627	DYRK1A	T694	R696C	696	Missense	proximal	2	no	34.703	33.206	EPSD	COSMIC	34.163	Loss
CMGC_DYRK_DYRK1_DYRK1A_ST	P10636	MAPT	Q13627	DYRK1A	T703	R696H	696	Missense	distal	-7	no	34.910	35.109	EPSD	COSMIC	34.163	Up-regulation
CMGC_DYRK_DYRK1_DYRK1A_ST	P10636	MAPT	Q13627	DYRK1A	T703	E708D	708	Missense	distal	5	no	34.910	33.031	EPSD	COSMIC	34.163	Loss
CMGC_DYRK_DYRK1_DYRK1A_ST	P10636	MAPT	Q13627	DYRK1A	T703	G706R	706	Missense	distal	3	no	34.910	34.892	EPSD	COSMIC	34.163	Down-regulation
CMGC_DYRK_DYRK1_DYRK1A_ST	P10636	MAPT	Q13627	DYRK1A	T703	V710M	710	Missense	distal	7	no	34.910	35.224	EPSD	COSMIC	34.163	Up-regulation
CMGC_DYRK_DYRK1_DYRK1A_ST	P10636	MAPT	Q13627	DYRK1A	T703	E708K	708	Missense	distal	5	no	34.910	34.924	EPSD	COSMIC	34.163	Up-regulation
CMGC_DYRK_DYRK1_DYRK1A_ST	P10636	MAPT	Q13627	DYRK1A	T703	R696C	696	Missense	distal	-7	no	34.910	35.835	EPSD	COSMIC	34.163	Up-regulation
CMGC_DYRK_DYRK1_DYRK1A_ST	P10636	MAPT	Q13627	DYRK1A	T703	V710A	710	Missense	distal	7	no	34.910	34.730	EPSD	COSMIC	34.163	Down-regulation
CMGC_DYRK_DYRK1_DYRK1A_ST	P10636	MAPT	Q13627	DYRK1A	T703	T703I	703	Missense	central	0	yes	34.910	0.000	EPSD	COSMIC	34.163	Loss
CMGC_DYRK_DYRK1_DYRK1A_ST	P10636	MAPT	Q13627	DYRK1A	S713	E708D	708	Missense	distal	-5	no	54.587	54.607	EPSD	COSMIC	34.163	Up-regulation
CMGC_DYRK_DYRK1_DYRK1A_ST	P10636	MAPT	Q13627	DYRK1A	S713	G706R	706	Missense	distal	-7	no	54.587	54.623	EPSD	COSMIC	34.163	Up-regulation
CMGC_DYRK_DYRK1_DYRK1A_ST	P10636	MAPT	Q13627	DYRK1A	S713	V710M	710	Missense	distal	-3	no	54.587	48.670	EPSD	COSMIC	34.163	Down-regulation
CMGC_DYRK_DYRK1_DYRK1A_ST	P10636	MAPT	Q13627	DYRK1A	S713	E708K	708	Missense	distal	-5	no	54.587	55.161	EPSD	COSMIC	34.163	Up-regulation
CMGC_DYRK_DYRK1_DYRK1A_ST	P10636	MAPT	Q13627	DYRK1A	S713	V710A	710	Missense	distal	-3	no	54.587	49.442	EPSD	COSMIC	34.163	Down-regulation
CMGC_DYRK_DYRK1_DYRK1A_ST	P10636	MAPT	Q13627	DYRK1A	S721	R723W	723	Missense	proximal	2	no	52.410	51.304	EPSD	COSMIC	34.163	Down-regulation
CMGC_DYRK_DYRK1_DYRK1A_ST	P10636	MAPT	Q13627	DYRK1A	S721	V728M	728	Missense	distal	7	no	52.410	52.725	EPSD	COSMIC	34.163	Up-regulation
CMGC_DYRK_DYRK1_DYRK1A_ST	P10636	MAPT	Q13627	DYRK1A	S721	V728A	728	Missense	distal	7	no	52.410	52.231	EPSD	COSMIC	34.163	Down-regulation
CMGC_DYRK_DYRK1_DYRK1A_ST	P10636	MAPT	Q13627	DYRK1A	S739	G732S	732	Missense	distal	-7	no	49.406	49.467	EPSD	COSMIC	34.163	Up-regulation
CMGC_DYRK_DYRK1_DYRK1A_ST	P10636	MAPT	Q13627	DYRK1A	S739	D735N	735	Missense	distal	-4	no	49.406	49.410	EPSD	COSMIC	34.163	Up-regulation
CMGC_DYRK_DYRK1_DYRK1A_ST	P10636	MAPT	Q13627	DYRK1A	S739	G732C	732	Missense	distal	-7	no	49.406	50.366	EPSD	COSMIC	34.163	Up-regulation
CMGC_DYRK_DYRK1_DYRK1A_ST	P10636	MAPT	Q13627	DYRK1A	S739	T744M	744	Missense	distal	5	no	49.406	42.699	EPSD	COSMIC	34.163	Down-regulation
CMGC_DYRK_DYRK1_DYRK1A_ST	P10636	MAPT	Q13627	DYRK1A	S739	A743T	743	Missense	distal	4	no	49.406	49.620	EPSD	COSMIC	34.163	Up-regulation
CMGC_DYRK_DYRK1_DYRK1A_ST	P49418	AMPH	Q13627	DYRK1A	T34	F39I	39	Missense	distal	5	no	36.276	36.435	EPSD	COSMIC	34.163	Up-regulation
CMGC_DYRK_DYRK1_DYRK1A_ST	P49418	AMPH	Q13627	DYRK1A	T260	R256G	256	Missense	distal	-4	no	38.916	38.881	EPSD	COSMIC;GDSC;CCLE	34.163	Down-regulation
CMGC_DYRK_DYRK1_DYRK1A_ST	P49418	AMPH	Q13627	DYRK1A	T260	P261A	261	Missense	proximal	1	no	38.916	8.771	EPSD	COSMIC	34.163	Loss
CMGC_DYRK_DYRK1_DYRK1A_ST	P49418	AMPH	Q13627	DYRK1A	T260	L255F	255	Missense	distal	-5	no	38.916	38.352	EPSD	COSMIC	34.163	Down-regulation
CMGC_DYRK_DYRK1_DYRK1A_ST	P49418	AMPH	Q13627	DYRK1A	T260	P267H	267	Missense	distal	7	no	38.916	40.464	EPSD	COSMIC	34.163	Up-regulation
CMGC_DYRK_DYRK1_DYRK1A_ST	P49418	AMPH	Q13627	DYRK1A	T260	P261Q	261	Missense	proximal	1	no	38.916	26.252	EPSD	COSMIC	34.163	Loss
CMGC_DYRK_DYRK1_DYRK1A_ST	P49418	AMPH	Q13627	DYRK1A	S262	R256G	256	Missense	distal	-6	no	45.398	45.307	EPSD	COSMIC;GDSC;CCLE	34.163	Down-regulation
CMGC_DYRK_DYRK1_DYRK1A_ST	P49418	AMPH	Q13627	DYRK1A	S262	P261A	261	Missense	proximal	-1	no	45.398	45.451	EPSD	COSMIC	34.163	Up-regulation
CMGC_DYRK_DYRK1_DYRK1A_ST	P49418	AMPH	Q13627	DYRK1A	S262	L255F	255	Missense	distal	-7	no	45.398	45.435	EPSD	COSMIC	34.163	Up-regulation
CMGC_DYRK_DYRK1_DYRK1A_ST	P49418	AMPH	Q13627	DYRK1A	S262	P267H	267	Missense	distal	5	no	45.398	41.241	EPSD	COSMIC	34.163	Down-regulation
CMGC_DYRK_DYRK1_DYRK1A_ST	P49418	AMPH	Q13627	DYRK1A	S262	P261Q	261	Missense	proximal	-1	no	45.398	45.397	EPSD	COSMIC	34.163	Down-regulation
CMGC_DYRK_DYRK1_DYRK1A_ST	P49418	AMPH	Q13627	DYRK1A	S272	H279R	279	Missense	distal	7	no	34.885	31.862	EPSD	COSMIC	34.163	Loss
CMGC_DYRK_DYRK1_DYRK1A_ST	P49418	AMPH	Q13627	DYRK1A	S272	P273L	273	Missense	proximal	1	no	34.885	-7.446	EPSD	COSMIC	34.163	Loss
CMGC_DYRK_DYRK1_DYRK1A_ST	P49418	AMPH	Q13627	DYRK1A	S272	P267H	267	Missense	distal	-5	no	34.885	34.011	EPSD	COSMIC	34.163	Loss
CMGC_DYRK_DYRK1_DYRK1A_ST	P49418	AMPH	Q13627	DYRK1A	S285	P283S	283	Missense	proximal	-2	no	36.285	31.349	EPSD	COSMIC	34.163	Loss
CMGC_DYRK_DYRK1_DYRK1A_ST	P49418	AMPH	Q13627	DYRK1A	S285	P286L	286	Missense	proximal	1	no	36.285	-6.045	EPSD	COSMIC	34.163	Loss
CMGC_DYRK_DYRK1_DYRK1A_ST	P49418	AMPH	Q13627	DYRK1A	S285	L281I	281	Missense	distal	-4	no	36.285	36.245	EPSD	COSMIC	34.163	Down-regulation
CMGC_DYRK_DYRK1_DYRK1A_ST	P49418	AMPH	Q13627	DYRK1A	S285	A284S	284	Missense	proximal	-1	no	36.285	36.053	EPSD	COSMIC	34.163	Down-regulation
CMGC_DYRK_DYRK1_DYRK1A_ST	P49418	AMPH	Q13627	DYRK1A	S285	H279R	279	Missense	distal	-6	no	36.285	36.902	EPSD	COSMIC	34.163	Up-regulation
CMGC_DYRK_DYRK1_DYRK1A_ST	P49418	AMPH	Q13627	DYRK1A	S293	P286L	286	Missense	distal	-7	no	65.700	66.702	EPSD;PhosphoSitePlus	COSMIC	34.163	Up-regulation
CMGC_DYRK_DYRK1_DYRK1A_ST	P49418	AMPH	Q13627	DYRK1A	T310	T312K	312	Missense	proximal	2	no	53.226	53.992	PhosphoSitePlus;EPSD	COSMIC	34.163	Up-regulation
CMGC_DYRK_DYRK1_DYRK1A_ST	P49418	AMPH	Q13627	DYRK1A	T310	T310A	310	Missense	central	0	yes	53.226	0.000	PhosphoSitePlus;EPSD	COSMIC	34.163	Loss
CMGC_DYRK_DYRK1_DYRK1A_ST	P49418	AMPH	Q13627	DYRK1A	T312	T312K	312	Missense	central	0	yes	51.793	0.000	EPSD;PhosphoSitePlus	COSMIC	34.163	Loss
CMGC_DYRK_DYRK1_DYRK1A_ST	P49418	AMPH	Q13627	DYRK1A	T312	T310A	310	Missense	proximal	-2	no	51.793	53.139	EPSD;PhosphoSitePlus	COSMIC	34.163	Up-regulation
CMGC_DYRK_DYRK1_DYRK1A_ST	P49418	AMPH	Q13627	DYRK1A	T336	S333R	333	Missense	distal	-3	no	33.209	41.799	EPSD	COSMIC	34.163	Gain
CMGC_DYRK_DYRK1_DYRK1A_ST	P49418	AMPH	Q13627	DYRK1A	T445	L452H	452	Missense	distal	7	no	45.689	45.578	EPSD	COSMIC	34.163	Down-regulation
CMGC_DYRK_DYRK1_DYRK1A_ST	P49418	AMPH	Q13627	DYRK1A	T445	P446L	446	Missense	proximal	1	no	45.689	3.358	EPSD	COSMIC	34.163	Loss
CMGC_DYRK_DYRK1_DYRK1A_ST	P49418	AMPH	Q13627	DYRK1A	T498	K496T	496	Missense	proximal	-2	no	35.201	35.608	EPSD	COSMIC	34.163	Up-regulation
CMGC_DYRK_DYRK1_DYRK1A_ST	P49418	AMPH	Q13627	DYRK1A	T498	A501T	501	Missense	distal	3	no	35.201	34.770	EPSD	COSMIC	34.163	Down-regulation
CMGC_DYRK_DYRK1_DYRK1A_ST	P49418	AMPH	Q13627	DYRK1A	T498	E495K	495	Missense	distal	-3	no	35.201	45.694	EPSD	COSMIC	34.163	Up-regulation
CMGC_DYRK_DYRK1_DYRK1A_ST	P49418	AMPH	Q13627	DYRK1A	T498	G504R	504	Missense	distal	6	no	35.201	35.206	EPSD	COSMIC	34.163	Up-regulation
CMGC_DYRK_DYRK1_DYRK1A_ST	P49418	AMPH	Q13627	DYRK1A	T498	A497V	497	Missense	proximal	-1	no	35.201	35.746	EPSD	COSMIC	34.163	Up-regulation
CMGC_DYRK_DYRK1_DYRK1A_ST	P53805	RCAN1	Q13627	DYRK1A	S167	P169L	169	Missense	proximal	2	no	60.157	59.656	EPSD;PhosphoSitePlus	COSMIC	34.163	Down-regulation
CMGC_DYRK_DYRK1_DYRK1A_ST	P53805	RCAN1	Q13627	DYRK1A	S167	P168L	168	Missense	proximal	1	no	60.157	17.826	EPSD;PhosphoSitePlus	COSMIC	34.163	Loss
CMGC_DYRK_DYRK1_DYRK1A_ST	P53805	RCAN1	Q13627	DYRK1A	S167	P165L	165	Missense	proximal	-2	no	60.157	46.430	EPSD;PhosphoSitePlus	COSMIC	34.163	Down-regulation
CMGC_DYRK_DYRK1_DYRK1A_ST	P53805	RCAN1	Q13627	DYRK1A	S191	L186Q	186	Missense	distal	-5	no	34.519	35.279	EPSD	COSMIC	34.163	Up-regulation
CMGC_DYRK_DYRK1_DYRK1A_ST	P53805	RCAN1	Q13627	DYRK1A	S191	S191F	191	Missense	central	0	yes	34.519	0.000	EPSD	COSMIC	34.163	Loss
CMGC_DYRK_DYRK1_DYRK1A_ST	P53805	RCAN1	Q13627	DYRK1A	T247	P244L	244	Missense	distal	-3	no	45.164	43.170	PhosphoSitePlus;EPSD	COSMIC	34.163	Down-regulation
CMGC_DYRK_DYRK1_DYRK1A_ST	P53805	RCAN1	Q13627	DYRK1A	T247	R243K	243	Missense	distal	-4	no	45.164	45.128	PhosphoSitePlus;EPSD	COSMIC;GDSC;CCLE	34.163	Down-regulation
CMGC_DYRK_DYRK1_DYRK1A_ST	P53805	RCAN1	Q13627	DYRK1A	T247	T247M	247	Missense	central	0	yes	45.164	0.000	PhosphoSitePlus;EPSD	COSMIC;GDSC;CCLE	34.163	Loss
CMGC_DYRK_DYRK1_DYRK1A_ST	P24928	POLR2A	Q13627	DYRK1A	S27	G24R	24	Missense	distal	-3	no	52.809	62.004	EPSD	COSMIC	34.163	Up-regulation
CMGC_DYRK_DYRK1_DYRK1A_ST	P24928	POLR2A	Q13627	DYRK1A	S27	R33Q	33	Missense	distal	6	no	52.809	52.816	EPSD	COSMIC;CCLE	34.163	Up-regulation
CMGC_DYRK_DYRK1_DYRK1A_ST	P24928	POLR2A	Q13627	DYRK1A	S27	G24A	24	Missense	distal	-3	no	52.809	47.587	EPSD	COSMIC	34.163	Down-regulation
CMGC_DYRK_DYRK1_DYRK1A_ST	P24928	POLR2A	Q13627	DYRK1A	S35	R33Q	33	Missense	proximal	-2	no	46.038	41.859	EPSD	COSMIC;CCLE	34.163	Down-regulation
CMGC_DYRK_DYRK1_DYRK1A_ST	P24928	POLR2A	Q13627	DYRK1A	T368	T365I	365	Missense	distal	-3	no	33.930	40.378	EPSD	COSMIC	34.163	Gain
CMGC_DYRK_DYRK1_DYRK1A_ST	P24928	POLR2A	Q13627	DYRK1A	T549	E556K	556	Missense	distal	7	no	45.971	47.601	EPSD	COSMIC	34.163	Up-regulation
CMGC_DYRK_DYRK1_DYRK1A_ST	P08151	GLI1	Q13627	DYRK1A	S84	S84F	84	Missense	central	0	yes	50.733	0.000	EPSD	COSMIC	34.163	Loss
CMGC_DYRK_DYRK1_DYRK1A_ST	P08151	GLI1	Q13627	DYRK1A	S84	L88M	88	Missense	distal	4	no	50.733	49.874	EPSD	COSMIC	34.163	Down-regulation
CMGC_DYRK_DYRK1_DYRK1A_ST	P08151	GLI1	Q13627	DYRK1A	S102	S105L	105	Missense	distal	3	no	38.498	37.983	EPSD	COSMIC	34.163	Down-regulation
CMGC_DYRK_DYRK1_DYRK1A_ST	P08151	GLI1	Q13627	DYRK1A	S102	P103R	103	Missense	proximal	1	no	38.498	23.417	EPSD	COSMIC	34.163	Loss
CMGC_DYRK_DYRK1_DYRK1A_ST	P08151	GLI1	Q13627	DYRK1A	S102	P103S	103	Missense	proximal	1	no	38.498	16.545	EPSD	COSMIC	34.163	Loss
CMGC_DYRK_DYRK1_DYRK1A_ST	P08151	GLI1	Q13627	DYRK1A	S102	V107I	107	Missense	distal	5	no	38.498	38.125	EPSD	COSMIC	34.163	Down-regulation
CMGC_DYRK_DYRK1_DYRK1A_ST	P08151	GLI1	Q13627	DYRK1A	S102	S105F	105	Missense	distal	3	no	38.498	37.941	EPSD	COSMIC	34.163	Down-regulation
CMGC_DYRK_DYRK1_DYRK1A_ST	P08151	GLI1	Q13627	DYRK1A	S102	L95M	95	Missense	distal	-7	no	38.498	38.738	EPSD	COSMIC	34.163	Up-regulation
CMGC_DYRK_DYRK1_DYRK1A_ST	P08151	GLI1	Q13627	DYRK1A	S102	S105Y	105	Missense	distal	3	no	38.498	38.079	EPSD	COSMIC;GDSC	34.163	Down-regulation
CMGC_DYRK_DYRK1_DYRK1A_ST	P08151	GLI1	Q13627	DYRK1A	S102	A108V	108	Missense	distal	6	no	38.498	38.572	EPSD	COSMIC	34.163	Up-regulation
CMGC_DYRK_DYRK1_DYRK1A_ST	P08151	GLI1	Q13627	DYRK1A	S102	S105T	105	Missense	distal	3	no	38.498	37.876	EPSD	COSMIC	34.163	Down-regulation
CMGC_DYRK_DYRK1_DYRK1A_ST	P08151	GLI1	Q13627	DYRK1A	S201	M199V	199	Missense	proximal	-2	no	26.243	41.831	EPSD	COSMIC	34.163	Gain
CMGC_DYRK_DYRK1_DYRK1A_ST	P08151	GLI1	Q13627	DYRK1A	S243	D240G	240	Missense	distal	-3	no	28.479	34.641	EPSD	COSMIC	34.163	Gain
CMGC_DYRK_DYRK1_DYRK1A_ST	P08151	GLI1	Q13627	DYRK1A	T296	R293H	293	Missense	distal	-3	no	44.163	28.831	EPSD	COSMIC	34.163	Loss
CMGC_DYRK_DYRK1_DYRK1A_ST	P08151	GLI1	Q13627	DYRK1A	T296	E298V	298	Missense	proximal	2	no	44.163	43.095	EPSD	COSMIC	34.163	Down-regulation
CMGC_DYRK_DYRK1_DYRK1A_ST	P08151	GLI1	Q13627	DYRK1A	T296	R293C	293	Missense	distal	-3	no	44.163	20.658	EPSD	COSMIC	34.163	Loss
CMGC_DYRK_DYRK1_DYRK1A_ST	P08151	GLI1	Q13627	DYRK1A	S408	S410C	410	Missense	proximal	2	no	54.087	53.089	PhosphoSitePlus	COSMIC	34.163	Down-regulation
CMGC_DYRK_DYRK1_DYRK1A_ST	P08151	GLI1	Q13627	DYRK1A	S408	P407S	407	Missense	proximal	-1	no	54.087	53.907	PhosphoSitePlus	COSMIC	34.163	Down-regulation
CMGC_DYRK_DYRK1_DYRK1A_ST	P08151	GLI1	Q13627	DYRK1A	S408	S408P	408	Missense	central	0	yes	54.087	0.000	PhosphoSitePlus	COSMIC	34.163	Loss
CMGC_DYRK_DYRK1_DYRK1A_ST	P08151	GLI1	Q13627	DYRK1A	S408	P414S	414	Missense	distal	6	no	54.087	54.096	PhosphoSitePlus	COSMIC	34.163	Up-regulation
CMGC_DYRK_DYRK1_DYRK1A_ST	P08151	GLI1	Q13627	DYRK1A	S408	R405Q	405	Missense	distal	-3	no	54.087	40.336	PhosphoSitePlus	COSMIC	34.163	Down-regulation
CMGC_DYRK_DYRK1_DYRK1A_ST	P08151	GLI1	Q13627	DYRK1A	S408	P414L	414	Missense	distal	6	no	54.087	54.159	PhosphoSitePlus	COSMIC	34.163	Up-regulation
CMGC_DYRK_DYRK1_DYRK1A_ST	P08151	GLI1	Q13627	DYRK1A	S408	K415Q	415	Missense	distal	7	no	54.087	52.389	PhosphoSitePlus	COSMIC	34.163	Down-regulation
CMGC_DYRK_DYRK1_DYRK1A_ST	P08151	GLI1	Q13627	DYRK1A	S545	S538C	538	Missense	distal	-7	no	47.505	48.404	EPSD	COSMIC	34.163	Up-regulation
CMGC_DYRK_DYRK1_DYRK1A_ST	P08151	GLI1	Q13627	DYRK1A	S545	R541C	541	Missense	distal	-4	no	47.505	47.479	EPSD	COSMIC;GDSC;CCLE	34.163	Down-regulation
CMGC_DYRK_DYRK1_DYRK1A_ST	P08151	GLI1	Q13627	DYRK1A	S545	S550G	550	Missense	distal	5	no	47.505	48.731	EPSD	COSMIC	34.163	Up-regulation
CMGC_DYRK_DYRK1_DYRK1A_ST	P08151	GLI1	Q13627	DYRK1A	S545	S548N	548	Missense	distal	3	no	47.505	47.095	EPSD	COSMIC	34.163	Down-regulation
CMGC_DYRK_DYRK1_DYRK1A_ST	P08151	GLI1	Q13627	DYRK1A	S602	R597G	597	Missense	distal	-5	no	44.149	43.294	EPSD	COSMIC	34.163	Down-regulation
CMGC_DYRK_DYRK1_DYRK1A_ST	P08151	GLI1	Q13627	DYRK1A	S602	A606V	606	Missense	distal	4	no	44.149	46.124	EPSD	COSMIC	34.163	Up-regulation
CMGC_DYRK_DYRK1_DYRK1A_ST	P08151	GLI1	Q13627	DYRK1A	S602	P603S	603	Missense	proximal	1	no	44.149	22.196	EPSD	COSMIC	34.163	Loss
CMGC_DYRK_DYRK1_DYRK1A_ST	P08151	GLI1	Q13627	DYRK1A	S602	A605S	605	Missense	distal	3	no	44.149	44.340	EPSD	COSMIC	34.163	Up-regulation
CMGC_DYRK_DYRK1_DYRK1A_ST	P08151	GLI1	Q13627	DYRK1A	S602	S602L	602	Missense	central	0	yes	44.149	0.000	EPSD	COSMIC	34.163	Loss
CMGC_DYRK_DYRK1_DYRK1A_ST	P08151	GLI1	Q13627	DYRK1A	S602	G598E	598	Missense	distal	-4	no	44.149	44.161	EPSD	COSMIC	34.163	Up-regulation
CMGC_DYRK_DYRK1_DYRK1A_ST	P08151	GLI1	Q13627	DYRK1A	S602	A596T	596	Missense	distal	-6	no	44.149	43.811	EPSD	COSMIC	34.163	Down-regulation
CMGC_DYRK_DYRK1_DYRK1A_ST	P08151	GLI1	Q13627	DYRK1A	S602	R597K	597	Missense	distal	-5	no	44.149	42.984	EPSD	COSMIC	34.163	Down-regulation
CMGC_DYRK_DYRK1_DYRK1A_ST	P08151	GLI1	Q13627	DYRK1A	S602	T601N	601	Missense	proximal	-1	no	44.149	45.477	EPSD	COSMIC	34.163	Up-regulation
CMGC_DYRK_DYRK1_DYRK1A_ST	P08151	GLI1	Q13627	DYRK1A	S602	G599R	599	Missense	distal	-3	no	44.149	53.343	EPSD	COSMIC	34.163	Up-regulation
CMGC_DYRK_DYRK1_DYRK1A_ST	P08151	GLI1	Q13627	DYRK1A	S602	A606T	606	Missense	distal	4	no	44.149	44.363	EPSD	COSMIC	34.163	Up-regulation
CMGC_DYRK_DYRK1_DYRK1A_ST	P08151	GLI1	Q13627	DYRK1A	S640	D647E	647	Missense	distal	7	no	43.812	42.129	EPSD	COSMIC	34.163	Down-regulation
CMGC_DYRK_DYRK1_DYRK1A_ST	P08151	GLI1	Q13627	DYRK1A	S640	R637G	637	Missense	distal	-3	no	43.812	34.617	EPSD	COSMIC	34.163	Down-regulation
CMGC_DYRK_DYRK1_DYRK1A_ST	P08151	GLI1	Q13627	DYRK1A	S640	G634R	634	Missense	distal	-6	no	43.812	43.902	EPSD	COSMIC	34.163	Up-regulation
CMGC_DYRK_DYRK1_DYRK1A_ST	P08151	GLI1	Q13627	DYRK1A	S934	L931R	931	Missense	distal	-3	no	34.044	47.399	EPSD	COSMIC	34.163	Gain
CMGC_DYRK_DYRK1_DYRK1A_ST	P08151	GLI1	Q13627	DYRK1A	S934	G933D	933	Missense	proximal	-1	no	34.044	34.463	EPSD	COSMIC	34.163	Gain
CMGC_DYRK_DYRK1_DYRK1A_ST	P08151	GLI1	Q13627	DYRK1A	S934	G932E	932	Missense	proximal	-2	no	34.044	36.550	EPSD	COSMIC;CCLE	34.163	Gain
CMGC_DYRK_DYRK1_DYRK1A_ST	P08151	GLI1	Q13627	DYRK1A	S934	R940C	940	Missense	distal	6	no	34.044	34.190	EPSD	COSMIC	34.163	Gain
CMGC_DYRK_DYRK1_DYRK1A_ST	P08151	GLI1	Q13627	DYRK1A	S937	R940Q	940	Missense	distal	3	no	44.905	44.603	EPSD	COSMIC	34.163	Down-regulation
CMGC_DYRK_DYRK1_DYRK1A_ST	P08151	GLI1	Q13627	DYRK1A	S937	R940W	940	Missense	distal	3	no	44.905	44.712	EPSD	COSMIC	34.163	Down-regulation
CMGC_DYRK_DYRK1_DYRK1A_ST	P08151	GLI1	Q13627	DYRK1A	S937	L931R	931	Missense	distal	-6	no	44.905	45.264	EPSD	COSMIC	34.163	Up-regulation
CMGC_DYRK_DYRK1_DYRK1A_ST	P08151	GLI1	Q13627	DYRK1A	S937	G933D	933	Missense	distal	-4	no	44.905	44.926	EPSD	COSMIC	34.163	Up-regulation
CMGC_DYRK_DYRK1_DYRK1A_ST	P08151	GLI1	Q13627	DYRK1A	S937	G932E	932	Missense	distal	-5	no	44.905	44.021	EPSD	COSMIC;CCLE	34.163	Down-regulation
CMGC_DYRK_DYRK1_DYRK1A_ST	P08151	GLI1	Q13627	DYRK1A	S937	R940C	940	Missense	distal	3	no	44.905	44.803	EPSD	COSMIC	34.163	Down-regulation
CMGC_DYRK_DYRK1_DYRK1A_ST	P08151	GLI1	Q13627	DYRK1A	S937	S934F	934	Missense	distal	-3	no	44.905	25.732	EPSD	COSMIC	34.163	Loss
CMGC_DYRK_DYRK1_DYRK1A_ST	P08151	GLI1	Q13627	DYRK1A	S937	A941T	941	Missense	distal	4	no	44.905	45.119	EPSD	COSMIC	34.163	Up-regulation
CMGC_DYRK_DYRK1_DYRK1A_ST	P08151	GLI1	Q13627	DYRK1A	S939	R940Q	940	Missense	proximal	1	no	39.170	41.587	EPSD	COSMIC	34.163	Up-regulation
CMGC_DYRK_DYRK1_DYRK1A_ST	P08151	GLI1	Q13627	DYRK1A	S939	R940W	940	Missense	proximal	1	no	39.170	22.405	EPSD	COSMIC	34.163	Loss
CMGC_DYRK_DYRK1_DYRK1A_ST	P08151	GLI1	Q13627	DYRK1A	S939	G933D	933	Missense	distal	-6	no	39.170	38.779	EPSD	COSMIC	34.163	Down-regulation
CMGC_DYRK_DYRK1_DYRK1A_ST	P08151	GLI1	Q13627	DYRK1A	S939	G932E	932	Missense	distal	-7	no	39.170	38.920	EPSD	COSMIC;CCLE	34.163	Down-regulation
CMGC_DYRK_DYRK1_DYRK1A_ST	P08151	GLI1	Q13627	DYRK1A	S939	R940C	940	Missense	proximal	1	no	39.170	22.878	EPSD	COSMIC	34.163	Loss
CMGC_DYRK_DYRK1_DYRK1A_ST	P08151	GLI1	Q13627	DYRK1A	S939	S934F	934	Missense	distal	-5	no	39.170	37.924	EPSD	COSMIC	34.163	Down-regulation
CMGC_DYRK_DYRK1_DYRK1A_ST	P08151	GLI1	Q13627	DYRK1A	S939	A941T	941	Missense	proximal	2	no	39.170	38.610	EPSD	COSMIC	34.163	Down-regulation
CMGC_DYRK_DYRK1_DYRK1A_ST	P08151	GLI1	Q13627	DYRK1A	S1071	R1068Q	1068	Missense	distal	-3	no	34.247	20.496	EPSD	COSMIC	34.163	Loss
CMGC_DYRK_DYRK1_DYRK1A_ST	P08151	GLI1	Q13627	DYRK1A	S1071	R1068W	1068	Missense	distal	-3	no	34.247	9.432	EPSD	COSMIC	34.163	Loss
CMGC_DYRK_DYRK1_DYRK1A_ST	P08151	GLI1	Q13627	DYRK1A	S1071	H1065N	1065	Missense	distal	-6	no	34.247	34.037	EPSD	COSMIC	34.163	Loss
CMGC_DYRK_DYRK1_DYRK1A_ST	P08151	GLI1	Q13627	DYRK1A	S1071	S1064P	1064	Missense	distal	-7	no	34.247	34.310	EPSD	COSMIC	34.163	Up-regulation
CMGC_DYRK_DYRK1_DYRK1A_ST	P08151	GLI1	Q13627	DYRK1A	S1071	P1077H	1077	Missense	distal	6	no	34.247	34.324	EPSD	COSMIC	34.163	Up-regulation
CMGC_DYRK_DYRK1_DYRK1A_ST	P08151	GLI1	Q13627	DYRK1A	T1074	R1068Q	1068	Missense	distal	-6	no	40.805	40.241	EPSD	COSMIC	34.163	Down-regulation
CMGC_DYRK_DYRK1_DYRK1A_ST	P08151	GLI1	Q13627	DYRK1A	T1074	R1068W	1068	Missense	distal	-6	no	40.805	40.165	EPSD	COSMIC	34.163	Down-regulation
CMGC_DYRK_DYRK1_DYRK1A_ST	P08151	GLI1	Q13627	DYRK1A	T1074	P1077H	1077	Missense	distal	3	no	40.805	40.889	EPSD	COSMIC	34.163	Up-regulation
CMGC_DYRK_DYRK1_DYRK1A_ST	Q13627	DYRK1A	Q13627	DYRK1A	S14	P19L	19	Missense	distal	5	no	40.592	39.706	EPSD	COSMIC	34.163	Down-regulation
CMGC_DYRK_DYRK1_DYRK1A_ST	Q13627	DYRK1A	Q13627	DYRK1A	S496	E500G	500	Missense	distal	4	no	39.455	38.305	EPSD	COSMIC	34.163	Down-regulation
CMGC_DYRK_DYRK1_DYRK1A_ST	Q13627	DYRK1A	Q13627	DYRK1A	S519	S512L	512	Missense	distal	-7	no	33.699	34.764	EPSD	COSMIC	34.163	Gain
CMGC_DYRK_DYRK1_DYRK1A_ST	Q13627	DYRK1A	Q13627	DYRK1A	S519	G517A	517	Missense	proximal	-2	no	33.699	37.714	EPSD	COSMIC	34.163	Gain
CMGC_DYRK_DYRK1_DYRK1A_ST	Q13627	DYRK1A	Q13627	DYRK1A	S519	G517V	517	Missense	proximal	-2	no	33.699	35.806	EPSD	COSMIC	34.163	Gain
CMGC_DYRK_DYRK1_DYRK1A_ST	Q13627	DYRK1A	Q13627	DYRK1A	T751	V755A	755	Missense	distal	4	no	40.532	38.556	EPSD	COSMIC	34.163	Down-regulation
CMGC_DYRK_DYRK1_DYRK1A_ST	Q13627	DYRK1A	Q13627	DYRK1A	S758	V755A	755	Missense	distal	-3	no	37.400	32.255	EPSD	COSMIC	34.163	Loss
CMGC_DYRK_DYRK1_DYRK1A_ST	O95644	NFATC1	Q13627	DYRK1A	S117	P113S	113	Missense	distal	-4	no	35.943	35.944	EPSD	COSMIC	34.163	Up-regulation
CMGC_DYRK_DYRK1_DYRK1A_ST	O95644	NFATC1	Q13627	DYRK1A	S117	A112T	112	Missense	distal	-5	no	35.943	35.935	EPSD	COSMIC	34.163	Down-regulation
CMGC_DYRK_DYRK1_DYRK1A_ST	O95644	NFATC1	Q13627	DYRK1A	S117	P118L	118	Missense	proximal	1	no	35.943	-6.388	EPSD	COSMIC	34.163	Loss
CMGC_DYRK_DYRK1_DYRK1A_ST	O95644	NFATC1	Q13627	DYRK1A	S151	K149R	149	Missense	proximal	-2	no	38.669	43.102	EPSD	COSMIC	34.163	Up-regulation
CMGC_DYRK_DYRK1_DYRK1A_ST	O95644	NFATC1	Q13627	DYRK1A	S151	S153F	153	Missense	proximal	2	no	38.669	37.283	EPSD	COSMIC	34.163	Down-regulation
CMGC_DYRK_DYRK1_DYRK1A_ST	O95644	NFATC1	Q13627	DYRK1A	S237	S237P	237	Missense	central	0	yes	54.613	0.000	EPSD	COSMIC	34.163	Loss
CMGC_DYRK_DYRK1_DYRK1A_ST	O95644	NFATC1	Q13627	DYRK1A	S237	S233F	233	Missense	distal	-4	no	54.613	54.589	EPSD	COSMIC	34.163	Down-regulation
CMGC_DYRK_DYRK1_DYRK1A_ST	O95644	NFATC1	Q13627	DYRK1A	S237	R235W	235	Missense	proximal	-2	no	54.613	42.051	EPSD	COSMIC	34.163	Down-regulation
CMGC_DYRK_DYRK1_DYRK1A_ST	O95644	NFATC1	Q13627	DYRK1A	S245	E249K	249	Missense	distal	4	no	35.442	35.085	EPSD	COSMIC	34.163	Down-regulation
CMGC_DYRK_DYRK1_DYRK1A_ST	O95644	NFATC1	Q13627	DYRK1A	S256	S257F	257	Missense	proximal	1	no	32.149	36.204	EPSD	COSMIC	34.163	Gain
CMGC_DYRK_DYRK1_DYRK1A_ST	O95644	NFATC1	Q13627	DYRK1A	S261	S257F	257	Missense	distal	-4	no	56.111	56.086	PhosphoSitePlus;EPSD	COSMIC	34.163	Down-regulation
CMGC_DYRK_DYRK1_DYRK1A_ST	O95644	NFATC1	Q13627	DYRK1A	S261	A260T	260	Missense	proximal	-1	no	56.111	55.409	PhosphoSitePlus;EPSD	COSMIC	34.163	Down-regulation
CMGC_DYRK_DYRK1_DYRK1A_ST	O95644	NFATC1	Q13627	DYRK1A	S261	R258I	258	Missense	distal	-3	no	56.111	44.949	PhosphoSitePlus;EPSD	COSMIC	34.163	Down-regulation
CMGC_DYRK_DYRK1_DYRK1A_ST	O95644	NFATC1	Q13627	DYRK1A	S261	R255K	255	Missense	distal	-6	no	56.111	55.713	PhosphoSitePlus;EPSD	COSMIC	34.163	Down-regulation
CMGC_DYRK_DYRK1_DYRK1A_ST	O95644	NFATC1	Q13627	DYRK1A	S278	T284M	284	Missense	distal	6	no	55.224	55.389	EPSD;PhosphoSitePlus	COSMIC	34.163	Up-regulation
CMGC_DYRK_DYRK1_DYRK1A_ST	O95644	NFATC1	Q13627	DYRK1A	T284	S286L	286	Missense	proximal	2	no	41.433	41.032	EPSD	COSMIC;GDSC	34.163	Down-regulation
CMGC_DYRK_DYRK1_DYRK1A_ST	O95644	NFATC1	Q13627	DYRK1A	T284	P287L	287	Missense	distal	3	no	41.433	41.439	EPSD	COSMIC	34.163	Up-regulation
CMGC_DYRK_DYRK1_DYRK1A_ST	O95644	NFATC1	Q13627	DYRK1A	T284	T284M	284	Missense	central	0	yes	41.433	0.000	EPSD	COSMIC	34.163	Loss
CMGC_DYRK_DYRK1_DYRK1A_ST	O95644	NFATC1	Q13627	DYRK1A	S286	S286L	286	Missense	central	0	yes	38.820	0.000	EPSD	COSMIC;GDSC	34.163	Loss
CMGC_DYRK_DYRK1_DYRK1A_ST	O95644	NFATC1	Q13627	DYRK1A	S286	R292W	292	Missense	distal	6	no	38.820	38.937	EPSD	COSMIC	34.163	Up-regulation
CMGC_DYRK_DYRK1_DYRK1A_ST	O95644	NFATC1	Q13627	DYRK1A	S286	P287L	287	Missense	proximal	1	no	38.820	-3.511	EPSD	COSMIC	34.163	Loss
CMGC_DYRK_DYRK1_DYRK1A_ST	O95644	NFATC1	Q13627	DYRK1A	S286	R292Q	292	Missense	distal	6	no	38.820	38.827	EPSD	COSMIC	34.163	Up-regulation
CMGC_DYRK_DYRK1_DYRK1A_ST	O95644	NFATC1	Q13627	DYRK1A	S286	T284M	284	Missense	proximal	-2	no	38.820	22.670	EPSD	COSMIC	34.163	Loss
CMGC_DYRK_DYRK1_DYRK1A_ST	O95644	NFATC1	Q13627	DYRK1A	S373	R378W	378	Missense	distal	5	no	38.427	34.625	EPSD	COSMIC	34.163	Down-regulation
CMGC_DYRK_DYRK1_DYRK1A_ST	O95644	NFATC1	Q13627	DYRK1A	S373	A367G	367	Missense	distal	-6	no	38.427	38.067	EPSD	COSMIC	34.163	Down-regulation
CMGC_DYRK_DYRK1_DYRK1A_ST	O95644	NFATC1	Q13627	DYRK1A	S373	E369K	369	Missense	distal	-4	no	38.427	38.413	EPSD	COSMIC;CCLE	34.163	Down-regulation
CMGC_DYRK_DYRK1_DYRK1A_ST	O95644	NFATC1	Q13627	DYRK1A	S373	S373C	373	Missense	central	0	yes	38.427	0.000	EPSD	COSMIC	34.163	Loss
CMGC_DYRK_DYRK1_DYRK1A_ST	O95644	NFATC1	Q13627	DYRK1A	S403	W396G	396	Missense	distal	-7	no	53.664	52.714	EPSD;PhosphoSitePlus	COSMIC	34.163	Down-regulation
CMGC_DYRK_DYRK1_DYRK1A_ST	O95644	NFATC1	Q13627	DYRK1A	S403	P410L	410	Missense	distal	7	no	53.664	55.323	EPSD;PhosphoSitePlus	COSMIC	34.163	Up-regulation
CMGC_DYRK_DYRK1_DYRK1A_ST	O95644	NFATC1	Q13627	DYRK1A	S403	S406F	406	Missense	distal	3	no	53.664	53.106	EPSD;PhosphoSitePlus	COSMIC;CCLE	34.163	Down-regulation
CMGC_DYRK_DYRK1_DYRK1A_ST	O95644	NFATC1	Q13627	DYRK1A	S403	A397S	397	Missense	distal	-6	no	53.664	53.681	EPSD;PhosphoSitePlus	COSMIC	34.163	Up-regulation
CMGC_DYRK_DYRK1_DYRK1A_ST	O95644	NFATC1	Q13627	DYRK1A	S409	P410L	410	Missense	proximal	1	no	52.496	10.166	EPSD;PhosphoSitePlus	COSMIC	34.163	Loss
CMGC_DYRK_DYRK1_DYRK1A_ST	O95644	NFATC1	Q13627	DYRK1A	S409	A414T	414	Missense	distal	5	no	52.496	54.359	EPSD;PhosphoSitePlus	COSMIC	34.163	Up-regulation
CMGC_DYRK_DYRK1_DYRK1A_ST	O95644	NFATC1	Q13627	DYRK1A	S409	S406F	406	Missense	distal	-3	no	52.496	33.324	EPSD;PhosphoSitePlus	COSMIC;CCLE	34.163	Loss
CMGC_DYRK_DYRK1_DYRK1A_ST	O95644	NFATC1	Q13627	DYRK1A	S409	P413H	413	Missense	distal	4	no	52.496	52.617	EPSD;PhosphoSitePlus	COSMIC;CCLE	34.163	Up-regulation
CMGC_DYRK_DYRK1_DYRK1A_ST	O95644	NFATC1	Q13627	DYRK1A	S723	V718L	718	Missense	distal	-5	no	42.887	42.103	EPSD	COSMIC	34.163	Down-regulation
CMGC_DYRK_DYRK1_DYRK1A_ST	O95644	NFATC1	Q13627	DYRK1A	S723	G716V	716	Missense	distal	-7	no	42.887	44.143	EPSD	COSMIC	34.163	Up-regulation
CMGC_DYRK_DYRK1_DYRK1A_ST	O95644	NFATC1	Q13627	DYRK1A	S723	L725F	725	Missense	proximal	2	no	42.887	41.901	EPSD	COSMIC	34.163	Down-regulation
CMGC_DYRK_DYRK1_DYRK1A_ST	O95644	NFATC1	Q13627	DYRK1A	S723	P724L	724	Missense	proximal	1	no	42.887	0.556	EPSD	COSMIC	34.163	Loss
CMGC_DYRK_DYRK1_DYRK1A_ST	O95644	NFATC1	Q13627	DYRK1A	S723	R727K	727	Missense	distal	4	no	42.887	44.763	EPSD	COSMIC	34.163	Up-regulation
CMGC_DYRK_DYRK1_DYRK1A_ST	O95644	NFATC1	Q13627	DYRK1A	S723	P717L	717	Missense	distal	-6	no	42.887	42.944	EPSD	COSMIC	34.163	Up-regulation
CMGC_DYRK_DYRK1_DYRK1A_ST	O95644	NFATC1	Q13627	DYRK1A	S765	P762L	762	Missense	distal	-3	no	44.443	42.450	EPSD	COSMIC	34.163	Down-regulation
CMGC_DYRK_DYRK1_DYRK1A_ST	O95644	NFATC1	Q13627	DYRK1A	S765	P762S	762	Missense	distal	-3	no	44.443	47.215	EPSD	COSMIC	34.163	Up-regulation
CMGC_DYRK_DYRK1_DYRK1A_ST	O95644	NFATC1	Q13627	DYRK1A	S765	D770N	770	Missense	distal	5	no	44.443	41.872	EPSD	COSMIC	34.163	Down-regulation
CMGC_DYRK_DYRK1_DYRK1A_ST	O95644	NFATC1	Q13627	DYRK1A	S765	A760T	760	Missense	distal	-5	no	44.443	44.435	EPSD	COSMIC	34.163	Down-regulation
CMGC_DYRK_DYRK1_DYRK1A_ST	O95644	NFATC1	Q13627	DYRK1A	S765	D770Y	770	Missense	distal	5	no	44.443	40.163	EPSD	COSMIC	34.163	Down-regulation
CMGC_DYRK_DYRK1_DYRK1A_ST	O95644	NFATC1	Q13627	DYRK1A	S765	V764M	764	Missense	proximal	-1	no	44.443	45.243	EPSD	COSMIC	34.163	Up-regulation
CMGC_DYRK_DYRK1_DYRK1A_ST	O95644	NFATC1	Q13627	DYRK1A	S772	A775S	775	Missense	distal	3	no	38.864	39.055	EPSD	COSMIC	34.163	Up-regulation
CMGC_DYRK_DYRK1_DYRK1A_ST	O95644	NFATC1	Q13627	DYRK1A	S772	D770N	770	Missense	proximal	-2	no	38.864	24.389	EPSD	COSMIC	34.163	Loss
CMGC_DYRK_DYRK1_DYRK1A_ST	O95644	NFATC1	Q13627	DYRK1A	S772	D770Y	770	Missense	proximal	-2	no	38.864	40.519	EPSD	COSMIC	34.163	Up-regulation
CMGC_DYRK_DYRK1_DYRK1A_ST	O95644	NFATC1	Q13627	DYRK1A	S813	P806L	806	Missense	distal	-7	no	33.353	34.355	EPSD	COSMIC	34.163	Gain
CMGC_DYRK_DYRK1_DYRK1A_ST	O95644	NFATC1	Q13627	DYRK1A	S887	T881M	881	Missense	distal	-6	no	43.310	42.212	EPSD	COSMIC	34.163	Down-regulation
CMGC_DYRK_DYRK1_DYRK1A_ST	O95644	NFATC1	Q13627	DYRK1A	S887	R893W	893	Missense	distal	6	no	43.310	43.427	EPSD	COSMIC	34.163	Up-regulation
CMGC_DYRK_DYRK1_DYRK1A_ST	O95644	NFATC1	Q13627	DYRK1A	S887	R883H	883	Missense	distal	-4	no	43.310	43.294	EPSD	COSMIC	34.163	Down-regulation
CMGC_DYRK_DYRK1_DYRK1A_ST	O95644	NFATC1	Q13627	DYRK1A	S887	A890V	890	Missense	distal	3	no	43.310	42.908	EPSD	COSMIC	34.163	Down-regulation
CMGC_DYRK_DYRK1_DYRK1A_ST	O95644	NFATC1	Q13627	DYRK1A	S903	A907V	907	Missense	distal	4	no	34.217	36.193	EPSD	COSMIC	34.163	Up-regulation
CMGC_DYRK_DYRK1_DYRK1A_ST	O95644	NFATC1	Q13627	DYRK1A	T912	A907V	907	Missense	distal	-5	no	37.004	37.436	EPSD	COSMIC	34.163	Up-regulation
CMGC_DYRK_DYRK1_DYRK1A_ST	O75533	SF3B1	Q13627	DYRK1A	T142	F136L	136	Missense	distal	-6	no	33.356	34.220	EPSD	COSMIC	34.163	Gain
CMGC_DYRK_DYRK1_DYRK1A_ST	O75533	SF3B1	Q13627	DYRK1A	T142	M147I	147	Missense	distal	5	no	33.356	34.552	EPSD	COSMIC	34.163	Gain
CMGC_DYRK_DYRK1_DYRK1A_ST	O75533	SF3B1	Q13627	DYRK1A	T223	P224S	224	Missense	proximal	1	no	41.387	19.434	EPSD	COSMIC	34.163	Loss
CMGC_DYRK_DYRK1_DYRK1A_ST	O75533	SF3B1	Q13627	DYRK1A	T223	Q220R	220	Missense	distal	-3	no	41.387	55.139	EPSD	COSMIC	34.163	Up-regulation
CMGC_DYRK_DYRK1_DYRK1A_ST	O75533	SF3B1	Q13627	DYRK1A	T223	S229Y	229	Missense	distal	6	no	41.387	41.503	EPSD	COSMIC	34.163	Up-regulation
CMGC_DYRK_DYRK1_DYRK1A_ST	O75533	SF3B1	Q13627	DYRK1A	T223	D219E	219	Missense	distal	-4	no	41.387	41.378	EPSD	COSMIC	34.163	Down-regulation
CMGC_DYRK_DYRK1_DYRK1A_ST	O75533	SF3B1	Q13627	DYRK1A	T244	R238H	238	Missense	distal	-6	no	35.354	34.737	EPSD	COSMIC	34.163	Down-regulation
CMGC_DYRK_DYRK1_DYRK1A_ST	O75533	SF3B1	Q13627	DYRK1A	T244	E243K	243	Missense	proximal	-1	no	35.354	36.228	EPSD	COSMIC	34.163	Up-regulation
CMGC_DYRK_DYRK1_DYRK1A_ST	O75533	SF3B1	Q13627	DYRK1A	T244	R238C	238	Missense	distal	-6	no	35.354	34.446	EPSD	COSMIC	34.163	Down-regulation
CMGC_DYRK_DYRK1_DYRK1A_ST	O75533	SF3B1	Q13627	DYRK1A	T261	S259R	259	Missense	proximal	-2	no	45.422	49.148	EPSD	COSMIC	34.163	Up-regulation
CMGC_DYRK_DYRK1_DYRK1A_ST	O75533	SF3B1	Q13627	DYRK1A	T261	P256L	256	Missense	distal	-5	no	45.422	43.985	EPSD	COSMIC	34.163	Down-regulation
CMGC_DYRK_DYRK1_DYRK1A_ST	O75533	SF3B1	Q13627	DYRK1A	T261	A263T	263	Missense	proximal	2	no	45.422	44.861	EPSD	COSMIC	34.163	Down-regulation
CMGC_DYRK_DYRK1_DYRK1A_ST	O75533	SF3B1	Q13627	DYRK1A	T267	G271D	271	Missense	distal	4	no	47.765	49.172	EPSD	COSMIC	34.163	Up-regulation
CMGC_DYRK_DYRK1_DYRK1A_ST	O75533	SF3B1	Q13627	DYRK1A	T267	A263T	263	Missense	distal	-4	no	47.765	47.767	EPSD	COSMIC	34.163	Up-regulation
CMGC_DYRK_DYRK1_DYRK1A_ST	O75533	SF3B1	Q13627	DYRK1A	T273	A277V	277	Missense	distal	4	no	54.664	56.640	PhosphoSitePlus;EPSD	COSMIC	34.163	Up-regulation
CMGC_DYRK_DYRK1_DYRK1A_ST	O75533	SF3B1	Q13627	DYRK1A	T273	G271D	271	Missense	proximal	-2	no	54.664	54.415	PhosphoSitePlus;EPSD	COSMIC	34.163	Down-regulation
CMGC_DYRK_DYRK1_DYRK1A_ST	O75533	SF3B1	Q13627	DYRK1A	T273	P279S	279	Missense	distal	6	no	54.664	54.674	PhosphoSitePlus;EPSD	COSMIC	34.163	Up-regulation
CMGC_DYRK_DYRK1_DYRK1A_ST	O75533	SF3B1	Q13627	DYRK1A	T278	A277V	277	Missense	proximal	-1	no	35.001	35.546	EPSD	COSMIC	34.163	Up-regulation
CMGC_DYRK_DYRK1_DYRK1A_ST	O75533	SF3B1	Q13627	DYRK1A	T278	G271D	271	Missense	distal	-7	no	35.001	35.835	EPSD	COSMIC	34.163	Up-regulation
CMGC_DYRK_DYRK1_DYRK1A_ST	O75533	SF3B1	Q13627	DYRK1A	T278	G282R	282	Missense	distal	4	no	35.001	33.917	EPSD	COSMIC	34.163	Loss
CMGC_DYRK_DYRK1_DYRK1A_ST	O75533	SF3B1	Q13627	DYRK1A	T278	P279S	279	Missense	proximal	1	no	35.001	13.048	EPSD	COSMIC	34.163	Loss
CMGC_DYRK_DYRK1_DYRK1A_ST	O75533	SF3B1	Q13627	DYRK1A	T296	K298I	298	Missense	proximal	2	no	39.539	37.893	EPSD	COSMIC	34.163	Down-regulation
CMGC_DYRK_DYRK1_DYRK1A_ST	O75533	SF3B1	Q13627	DYRK1A	T296	W293R	293	Missense	distal	-3	no	39.539	64.354	EPSD	COSMIC	34.163	Up-regulation
CMGC_DYRK_DYRK1_DYRK1A_ST	O75533	SF3B1	Q13627	DYRK1A	T296	N291I	291	Missense	distal	-5	no	39.539	40.641	EPSD	COSMIC	34.163	Up-regulation
CMGC_DYRK_DYRK1_DYRK1A_ST	O75533	SF3B1	Q13627	DYRK1A	T296	P297L	297	Missense	proximal	1	no	39.539	-2.792	EPSD	COSMIC	34.163	Loss
CMGC_DYRK_DYRK1_DYRK1A_ST	O75533	SF3B1	Q13627	DYRK1A	T296	D302E	302	Missense	distal	6	no	39.539	39.414	EPSD	COSMIC	34.163	Down-regulation
CMGC_DYRK_DYRK1_DYRK1A_ST	O75533	SF3B1	Q13627	DYRK1A	T296	N291Y	291	Missense	distal	-5	no	39.539	40.561	EPSD	COSMIC	34.163	Up-regulation
CMGC_DYRK_DYRK1_DYRK1A_ST	O75533	SF3B1	Q13627	DYRK1A	T303	K298I	298	Missense	distal	-5	no	45.884	45.549	EPSD	COSMIC	34.163	Down-regulation
CMGC_DYRK_DYRK1_DYRK1A_ST	O75533	SF3B1	Q13627	DYRK1A	T303	P304L	304	Missense	proximal	1	no	45.884	3.553	EPSD	COSMIC	34.163	Loss
CMGC_DYRK_DYRK1_DYRK1A_ST	O75533	SF3B1	Q13627	DYRK1A	T303	P297L	297	Missense	distal	-6	no	45.884	45.942	EPSD	COSMIC	34.163	Up-regulation
CMGC_DYRK_DYRK1_DYRK1A_ST	O75533	SF3B1	Q13627	DYRK1A	T303	H306Y	306	Missense	distal	3	no	45.884	45.904	EPSD	COSMIC	34.163	Up-regulation
CMGC_DYRK_DYRK1_DYRK1A_ST	O75533	SF3B1	Q13627	DYRK1A	T303	D302E	302	Missense	proximal	-1	no	45.884	44.959	EPSD	COSMIC	34.163	Down-regulation
CMGC_DYRK_DYRK1_DYRK1A_ST	O75533	SF3B1	Q13627	DYRK1A	T313	E312K	312	Missense	proximal	-1	no	37.729	38.603	EPSD	COSMIC	34.163	Up-regulation
CMGC_DYRK_DYRK1_DYRK1A_ST	O75533	SF3B1	Q13627	DYRK1A	T313	H306Y	306	Missense	distal	-7	no	37.729	39.100	EPSD	COSMIC	34.163	Up-regulation
CMGC_DYRK_DYRK1_DYRK1A_ST	O75533	SF3B1	Q13627	DYRK1A	T326	G330E	330	Missense	distal	4	no	45.726	46.876	EPSD	COSMIC	34.163	Up-regulation
CMGC_DYRK_DYRK1_DYRK1A_ST	O75533	SF3B1	Q13627	DYRK1A	S344	G347V	347	Missense	distal	3	no	40.717	40.385	EPSD	COSMIC	34.163	Down-regulation
CMGC_DYRK_DYRK1_DYRK1A_ST	O75533	SF3B1	Q13627	DYRK1A	S344	T350S	350	Missense	distal	6	no	40.717	40.729	EPSD	COSMIC	34.163	Up-regulation
CMGC_DYRK_DYRK1_DYRK1A_ST	O75533	SF3B1	Q13627	DYRK1A	T350	G347V	347	Missense	distal	-3	no	42.910	42.833	EPSD	COSMIC	34.163	Down-regulation
CMGC_DYRK_DYRK1_DYRK1A_ST	O75533	SF3B1	Q13627	DYRK1A	T350	P355S	355	Missense	distal	5	no	42.910	42.971	EPSD	COSMIC	34.163	Up-regulation
CMGC_DYRK_DYRK1_DYRK1A_ST	O75533	SF3B1	Q13627	DYRK1A	T350	K357M	357	Missense	distal	7	no	42.910	43.387	EPSD	COSMIC	34.163	Up-regulation
CMGC_DYRK_DYRK1_DYRK1A_ST	O75533	SF3B1	Q13627	DYRK1A	T350	L353V	353	Missense	distal	3	no	42.910	42.832	EPSD	COSMIC	34.163	Down-regulation
CMGC_DYRK_DYRK1_DYRK1A_ST	O75533	SF3B1	Q13627	DYRK1A	T354	G347V	347	Missense	distal	-7	no	42.439	43.695	EPSD	COSMIC	34.163	Up-regulation
CMGC_DYRK_DYRK1_DYRK1A_ST	O75533	SF3B1	Q13627	DYRK1A	T354	P355S	355	Missense	proximal	1	no	42.439	20.486	EPSD	COSMIC	34.163	Loss
CMGC_DYRK_DYRK1_DYRK1A_ST	O75533	SF3B1	Q13627	DYRK1A	T354	K357M	357	Missense	distal	3	no	42.439	42.305	EPSD	COSMIC	34.163	Down-regulation
CMGC_DYRK_DYRK1_DYRK1A_ST	O75533	SF3B1	Q13627	DYRK1A	T354	T350S	350	Missense	distal	-4	no	42.439	42.430	EPSD	COSMIC	34.163	Down-regulation
CMGC_DYRK_DYRK1_DYRK1A_ST	O75533	SF3B1	Q13627	DYRK1A	T354	L353V	353	Missense	proximal	-1	no	42.439	42.812	EPSD	COSMIC	34.163	Up-regulation
CMGC_DYRK_DYRK1_DYRK1A_ST	O75533	SF3B1	Q13627	DYRK1A	T358	P355S	355	Missense	distal	-3	no	39.400	42.172	EPSD	COSMIC	34.163	Up-regulation
CMGC_DYRK_DYRK1_DYRK1A_ST	O75533	SF3B1	Q13627	DYRK1A	T358	K357M	357	Missense	proximal	-1	no	39.400	40.037	EPSD	COSMIC	34.163	Up-regulation
CMGC_DYRK_DYRK1_DYRK1A_ST	O75533	SF3B1	Q13627	DYRK1A	T358	P363S	363	Missense	distal	5	no	39.400	39.461	EPSD	COSMIC	34.163	Up-regulation
CMGC_DYRK_DYRK1_DYRK1A_ST	O75533	SF3B1	Q13627	DYRK1A	T358	A364V	364	Missense	distal	6	no	39.400	39.473	EPSD	COSMIC	34.163	Up-regulation
CMGC_DYRK_DYRK1_DYRK1A_ST	O75533	SF3B1	Q13627	DYRK1A	T358	L353V	353	Missense	distal	-5	no	39.400	40.183	EPSD	COSMIC	34.163	Up-regulation
CMGC_DYRK_DYRK1_DYRK1A_ST	O75533	SF3B1	Q13627	DYRK1A	T362	M367V	367	Missense	distal	5	no	32.995	34.565	EPSD	COSMIC	34.163	Gain
CMGC_DYRK_DYRK1_DYRK1A_ST	O75533	SF3B1	Q13627	DYRK1A	S400	E394D	394	Missense	distal	-6	no	54.946	54.325	EPSD	COSMIC	34.163	Down-regulation
CMGC_DYRK_DYRK1_DYRK1A_ST	O75533	SF3B1	Q13627	DYRK1A	S400	E402G	402	Missense	proximal	2	no	54.946	55.207	EPSD	COSMIC	34.163	Up-regulation
CMGC_DYRK_DYRK1_DYRK1A_ST	O75533	SF3B1	Q13627	DYRK1A	S400	D393Y	393	Missense	distal	-7	no	54.946	55.718	EPSD	COSMIC	34.163	Up-regulation
CMGC_DYRK_DYRK1_DYRK1A_ST	O75533	SF3B1	Q13627	DYRK1A	S400	R397H	397	Missense	distal	-3	no	54.946	39.614	EPSD	COSMIC	34.163	Down-regulation
CMGC_DYRK_DYRK1_DYRK1A_ST	O75533	SF3B1	Q13627	DYRK1A	S488	R495S	495	Missense	distal	7	no	39.998	40.978	EPSD	COSMIC	34.163	Up-regulation
CMGC_DYRK_DYRK1_DYRK1A_ST	O75533	SF3B1	Q13627	DYRK1A	S488	E491G	491	Missense	distal	3	no	39.998	40.046	EPSD	COSMIC	34.163	Up-regulation
CMGC_DYRK_DYRK1_DYRK1A_ST	O75533	SF3B1	Q13627	DYRK1A	S488	D483Y	483	Missense	distal	-5	no	39.998	40.137	EPSD	COSMIC	34.163	Up-regulation
CMGC_DYRK_DYRK1_DYRK1A_ST	O75533	SF3B1	Q13627	DYRK1A	S488	R495I	495	Missense	distal	7	no	39.998	43.271	EPSD	COSMIC	34.163	Up-regulation
CMGC_DYRK_DYRK1_DYRK1A_ST	O75533	SF3B1	Q13627	DYRK1A	S488	V482I	482	Missense	distal	-6	no	39.998	40.466	EPSD	COSMIC	34.163	Up-regulation
CMGC_DYRK_DYRK1_DYRK1A_ST	O75533	SF3B1	Q13627	DYRK1A	T508	N506S	506	Missense	proximal	-2	no	18.107	35.800	EPSD	COSMIC	34.163	Gain
CMGC_DYRK_DYRK1_DYRK1A_ST	O75533	SF3B1	Q13627	DYRK1A	S541	D546Y	546	Missense	distal	5	no	36.901	32.621	EPSD	COSMIC	34.163	Loss
CMGC_DYRK_DYRK1_DYRK1A_ST	O75533	SF3B1	Q13627	DYRK1A	S541	L536F	536	Missense	distal	-5	no	36.901	36.337	EPSD	COSMIC	34.163	Down-regulation
CMGC_DYRK_DYRK1_DYRK1A_ST	O75533	SF3B1	Q13627	DYRK1A	S541	E545Q	545	Missense	distal	4	no	36.901	36.923	EPSD	COSMIC	34.163	Up-regulation
CMGC_DYRK_DYRK1_DYRK1A_ST	O75533	SF3B1	Q13627	DYRK1A	S541	S541F	541	Missense	central	0	yes	36.901	0.000	EPSD	COSMIC	34.163	Loss
CMGC_DYRK_DYRK1_DYRK1A_ST	O75533	SF3B1	Q13627	DYRK1A	T1080	A1085V	1085	Missense	distal	5	no	34.821	31.546	EPSD	COSMIC	34.163	Loss
CMGC_DYRK_DYRK1_DYRK1A_ST	O75533	SF3B1	Q13627	DYRK1A	T1080	Y1083F	1083	Missense	distal	3	no	34.821	34.682	EPSD	COSMIC	34.163	Down-regulation
CMGC_DYRK_DYRK1_DYRK1A_ST	O75533	SF3B1	Q13627	DYRK1A	T1080	A1076T	1076	Missense	distal	-4	no	34.821	34.823	EPSD	COSMIC	34.163	Up-regulation
CMGC_DYRK_DYRK1_DYRK1A_ST	O75533	SF3B1	Q13627	DYRK1A	T1080	V1078A	1078	Missense	proximal	-2	no	34.821	36.729	EPSD	COSMIC	34.163	Up-regulation
CMGC_DYRK_DYRK1_DYRK1A_ST	O75533	SF3B1	Q13627	DYRK1A	T1080	F1081S	1081	Missense	proximal	1	no	34.821	30.766	EPSD	COSMIC	34.163	Loss
CMGC_DYRK_DYRK1_DYRK1A_ST	O75533	SF3B1	Q13627	DYRK1A	S1271	I1272V	1272	Missense	proximal	1	no	43.021	43.421	EPSD	COSMIC	34.163	Up-regulation
CMGC_DYRK_DYRK1_DYRK1A_ST	O75533	SF3B1	Q13627	DYRK1A	S1271	N1270K	1270	Missense	proximal	-1	no	43.021	43.101	EPSD	COSMIC	34.163	Up-regulation
CMGC_DYRK_DYRK1_DYRK1A_ST	O75533	SF3B1	Q13627	DYRK1A	S1271	D1278Y	1278	Missense	distal	7	no	43.021	43.924	EPSD	COSMIC	34.163	Up-regulation
CMGC_DYRK_DYRK1_DYRK1A_ST	O75533	SF3B1	Q13627	DYRK1A	S1271	W1266R	1266	Missense	distal	-5	no	43.021	45.277	EPSD	COSMIC	34.163	Up-regulation
CMGC_DYRK_DYRK1_DYRK1A_ST	O75533	SF3B1	Q13627	DYRK1A	S1271	K1267I	1267	Missense	distal	-4	no	43.021	42.999	EPSD	COSMIC	34.163	Down-regulation
CMGC_DYRK_DYRK1_DYRK1A_ST	O75533	SF3B1	Q13627	DYRK1A	S1271	G1275A	1275	Missense	distal	4	no	43.021	43.547	EPSD	COSMIC	34.163	Up-regulation
CMGC_DYRK_DYRK1_DYRK1A_ST	Q96S94	CCNL2	Q13627	DYRK1A	S25	A19G	19	Missense	distal	-6	no	41.427	41.068	EPSD	COSMIC	34.163	Down-regulation
CMGC_DYRK_DYRK1_DYRK1A_ST	Q96S94	CCNL2	Q13627	DYRK1A	S32	V35A	35	Missense	distal	3	no	43.486	43.887	EPSD	COSMIC	34.163	Up-regulation
CMGC_DYRK_DYRK1_DYRK1A_ST	Q96S94	CCNL2	Q13627	DYRK1A	S32	D39G	39	Missense	distal	7	no	43.486	41.786	EPSD	COSMIC	34.163	Down-regulation
CMGC_DYRK_DYRK1_DYRK1A_ST	Q96S94	CCNL2	Q13627	DYRK1A	S32	G34R	34	Missense	proximal	2	no	43.486	43.526	EPSD	COSMIC	34.163	Up-regulation
CMGC_DYRK_DYRK1_DYRK1A_ST	Q96S94	CCNL2	Q13627	DYRK1A	S32	G34E	34	Missense	proximal	2	no	43.486	43.225	EPSD	COSMIC	34.163	Down-regulation
CMGC_DYRK_DYRK1_DYRK1A_ST	Q96S94	CCNL2	Q13627	DYRK1A	S330	P331S	331	Missense	proximal	1	no	53.095	31.142	EPSD;PhosphoSitePlus	COSMIC	34.163	Loss
CMGC_DYRK_DYRK1_DYRK1A_ST	Q96S94	CCNL2	Q13627	DYRK1A	S338	P331S	331	Missense	distal	-7	no	53.574	53.511	PhosphoSitePlus;EPSD	COSMIC	34.163	Down-regulation
CMGC_DYRK_DYRK1_DYRK1A_ST	Q96S94	CCNL2	Q13627	DYRK1A	S351	K356R	356	Missense	distal	5	no	37.489	37.533	EPSD	COSMIC	34.163	Up-regulation
CMGC_DYRK_DYRK1_DYRK1A_ST	Q96S94	CCNL2	Q13627	DYRK1A	S351	R358T	358	Missense	distal	7	no	37.489	39.636	EPSD	COSMIC	34.163	Up-regulation
CMGC_DYRK_DYRK1_DYRK1A_ST	Q96S94	CCNL2	Q13627	DYRK1A	T355	K356R	356	Missense	proximal	1	no	36.870	35.385	EPSD	COSMIC	34.163	Down-regulation
CMGC_DYRK_DYRK1_DYRK1A_ST	Q96S94	CCNL2	Q13627	DYRK1A	T355	A362T	362	Missense	distal	7	no	36.870	35.876	EPSD	COSMIC	34.163	Down-regulation
CMGC_DYRK_DYRK1_DYRK1A_ST	Q96S94	CCNL2	Q13627	DYRK1A	T355	R358T	358	Missense	distal	3	no	36.870	36.527	EPSD	COSMIC	34.163	Down-regulation
CMGC_DYRK_DYRK1_DYRK1A_ST	Q96S94	CCNL2	Q13627	DYRK1A	T355	G361S	361	Missense	distal	6	no	36.870	36.937	EPSD	COSMIC	34.163	Up-regulation
CMGC_DYRK_DYRK1_DYRK1A_ST	Q96S94	CCNL2	Q13627	DYRK1A	T355	E360D	360	Missense	distal	5	no	36.870	34.991	EPSD	COSMIC;GDSC	34.163	Down-regulation
CMGC_DYRK_DYRK1_DYRK1A_ST	Q96S94	CCNL2	Q13627	DYRK1A	S369	V371L	371	Missense	proximal	2	no	54.235	54.704	EPSD;PhosphoSitePlus	COSMIC;GDSC;CCLE	34.163	Up-regulation
CMGC_DYRK_DYRK1_DYRK1A_ST	Q96S94	CCNL2	Q13627	DYRK1A	S369	A362T	362	Missense	distal	-7	no	54.235	53.637	EPSD;PhosphoSitePlus	COSMIC	34.163	Down-regulation
CMGC_DYRK_DYRK1_DYRK1A_ST	Q96S94	CCNL2	Q13627	DYRK1A	S369	A365V	365	Missense	distal	-4	no	54.235	54.196	EPSD;PhosphoSitePlus	COSMIC	34.163	Down-regulation
CMGC_DYRK_DYRK1_DYRK1A_ST	Q96S94	CCNL2	Q13627	DYRK1A	S369	P375S	375	Missense	distal	6	no	54.235	54.245	EPSD;PhosphoSitePlus	COSMIC	34.163	Up-regulation
CMGC_DYRK_DYRK1_DYRK1A_ST	Q96S94	CCNL2	Q13627	DYRK1A	S394	S394P	394	Missense	central	0	yes	38.187	0.000	EPSD	COSMIC;GDSC;CCLE	34.163	Loss
CMGC_DYRK_DYRK1_DYRK1A_ST	Q96S94	CCNL2	Q13627	DYRK1A	S394	S392L	392	Missense	proximal	-2	no	38.187	29.396	EPSD	COSMIC	34.163	Loss
CMGC_DYRK_DYRK1_DYRK1A_ST	Q96S94	CCNL2	Q13627	DYRK1A	S400	S394P	394	Missense	distal	-6	no	53.626	52.922	EPSD	COSMIC;GDSC;CCLE	34.163	Down-regulation
CMGC_DYRK_DYRK1_DYRK1A_ST	Q96S94	CCNL2	Q13627	DYRK1A	S415	R422W	422	Missense	distal	7	no	32.833	36.631	EPSD	COSMIC	34.163	Gain
CMGC_DYRK_DYRK1_DYRK1A_ST	Q96S94	CCNL2	Q13627	DYRK1A	S417	S417L	417	Missense	central	0	yes	37.137	0.000	EPSD	COSMIC	34.163	Loss
CMGC_DYRK_DYRK1_DYRK1A_ST	Q96S94	CCNL2	Q13627	DYRK1A	S417	R420H	420	Missense	distal	3	no	37.137	36.978	EPSD	COSMIC	34.163	Down-regulation
CMGC_DYRK_DYRK1_DYRK1A_ST	Q96S94	CCNL2	Q13627	DYRK1A	S417	R422W	422	Missense	distal	5	no	37.137	33.336	EPSD	COSMIC	34.163	Loss
CMGC_DYRK_DYRK1_DYRK1A_ST	Q96S94	CCNL2	Q13627	DYRK1A	S423	S417L	417	Missense	distal	-6	no	35.042	34.396	EPSD	COSMIC	34.163	Down-regulation
CMGC_DYRK_DYRK1_DYRK1A_ST	Q96S94	CCNL2	Q13627	DYRK1A	S423	R420H	420	Missense	distal	-3	no	35.042	19.710	EPSD	COSMIC	34.163	Loss
CMGC_DYRK_DYRK1_DYRK1A_ST	Q96S94	CCNL2	Q13627	DYRK1A	S423	R422W	422	Missense	proximal	-1	no	35.042	36.199	EPSD	COSMIC	34.163	Up-regulation
CMGC_DYRK_DYRK1_DYRK1A_ST	Q96S94	CCNL2	Q13627	DYRK1A	S427	R434P	434	Missense	distal	7	no	57.911	59.386	EPSD	COSMIC	34.163	Up-regulation
CMGC_DYRK_DYRK1_DYRK1A_ST	Q96S94	CCNL2	Q13627	DYRK1A	S427	R420H	420	Missense	distal	-7	no	57.911	58.110	EPSD	COSMIC	34.163	Up-regulation
CMGC_DYRK_DYRK1_DYRK1A_ST	Q96S94	CCNL2	Q13627	DYRK1A	S427	R422W	422	Missense	distal	-5	no	57.911	55.654	EPSD	COSMIC	34.163	Down-regulation
CMGC_DYRK_DYRK1_DYRK1A_ST	Q96S94	CCNL2	Q13627	DYRK1A	S467	R462Q	462	Missense	distal	-5	no	36.486	35.334	EPSD	COSMIC	34.163	Down-regulation
CMGC_DYRK_DYRK1_DYRK1A_ST	Q96S94	CCNL2	Q13627	DYRK1A	S467	R468C	468	Missense	proximal	1	no	36.486	20.193	EPSD	COSMIC	34.163	Loss
CMGC_DYRK_DYRK1_DYRK1A_ST	Q96S94	CCNL2	Q13627	DYRK1A	S467	S461F	461	Missense	distal	-6	no	36.486	34.976	EPSD	COSMIC	34.163	Down-regulation
CMGC_DYRK_DYRK1_DYRK1A_ST	Q96S94	CCNL2	Q13627	DYRK1A	S467	R464Q	464	Missense	distal	-3	no	36.486	22.734	EPSD	COSMIC	34.163	Loss
CMGC_DYRK_DYRK1_DYRK1A_ST	Q96S94	CCNL2	Q13627	DYRK1A	S471	R464Q	464	Missense	distal	-7	no	33.762	34.264	EPSD	COSMIC	34.163	Gain
CMGC_DYRK_DYRK1_DYRK1A_ST	Q96S94	CCNL2	Q13627	DYRK1A	S473	P480S	480	Missense	distal	7	no	44.312	43.816	EPSD	COSMIC	34.163	Down-regulation
CMGC_DYRK_DYRK1_DYRK1A_ST	Q96S94	CCNL2	Q13627	DYRK1A	S473	R468C	468	Missense	distal	-5	no	44.312	42.311	EPSD	COSMIC	34.163	Down-regulation
CMGC_DYRK_DYRK1_DYRK1A_ST	Q96S94	CCNL2	Q13627	DYRK1A	S473	P480L	480	Missense	distal	7	no	44.312	45.971	EPSD	COSMIC;GDSC	34.163	Up-regulation
CMGC_DYRK_DYRK1_DYRK1A_ST	Q52LA3	LIN52	Q13627	DYRK1A	S28	A27D	27	Missense	proximal	-1	no	53.810	54.568	PhosphoSitePlus	COSMIC	34.163	Up-regulation
CMGC_DYRK_DYRK1_DYRK1A_ST	Q52LA3	LIN52	Q13627	DYRK1A	S53	E60K	60	Missense	distal	7	no	46.625	48.256	EPSD	COSMIC	34.163	Up-regulation
CMGC_DYRK_DYRK1_DYRK1A_ST	Q52LA3	LIN52	Q13627	DYRK1A	S53	K56T	56	Missense	distal	3	no	46.625	46.325	EPSD	COSMIC	34.163	Down-regulation
CMGC_DYRK_DYRK1_DYRK1A_ST	Q52LA3	LIN52	Q13627	DYRK1A	S53	A59T	59	Missense	distal	6	no	46.625	46.580	EPSD	COSMIC;GDSC;CCLE	34.163	Down-regulation
CMGC_DYRK_DYRK1_DYRK1A_ST	O43597	SPRY2	Q13627	DYRK1A	T75	Q76E	76	Missense	proximal	1	no	54.771	48.428	PhosphoSitePlus	COSMIC	34.163	Down-regulation
CMGC_DYRK_DYRK1_DYRK1A_ST	O43597	SPRY2	Q13627	DYRK1A	T75	R72C	72	Missense	distal	-3	no	54.771	31.266	PhosphoSitePlus	COSMIC	34.163	Loss
CMGC_DYRK_DYRK1_DYRK1A_ST	O43597	SPRY2	Q13627	DYRK1A	T75	P71L	71	Missense	distal	-4	no	54.771	54.768	PhosphoSitePlus	COSMIC	34.163	Down-regulation
CMGC_DYRK_DYRK1_DYRK1A_ST	O43597	SPRY2	Q13627	DYRK1A	S110	T113M	113	Missense	distal	3	no	34.027	34.193	EPSD	COSMIC	34.163	Gain
CMGC_DYRK_DYRK1_DYRK1A_ST	O43597	SPRY2	Q13627	DYRK1A	S142	S141F	141	Missense	proximal	-1	no	33.573	35.562	EPSD	COSMIC	34.163	Gain
CMGC_DYRK_DYRK1_DYRK1A_ST	O43597	SPRY2	Q13627	DYRK1A	S156	E157K	157	Missense	proximal	1	no	30.503	35.914	EPSD	COSMIC	34.163	Gain
CMGC_DYRK_DYRK1_DYRK1A_ST	P04637	TP53	Q13627	DYRK1A	S15	E11Q	11	Missense	distal	-4	no	53.550	53.548	PhosphoSitePlus	COSMIC;GDSC;CCLE	34.163	Down-regulation
CMGC_DYRK_DYRK1_DYRK1A_ST	P04637	TP53	Q13627	DYRK1A	S15	S20L	20	Missense	distal	5	no	53.550	52.603	PhosphoSitePlus	COSMIC	34.163	Down-regulation
CMGC_DYRK_DYRK1_DYRK1A_ST	P04637	TP53	Q13627	DYRK1A	S15	Q16L	16	Missense	proximal	1	no	53.550	23.883	PhosphoSitePlus	COSMIC;GDSC;CCLE	34.163	Loss
CMGC_DYRK_DYRK1_DYRK1A_ST	P04637	TP53	Q13627	DYRK1A	S15	P13S	13	Missense	proximal	-2	no	53.550	48.613	PhosphoSitePlus	COSMIC	34.163	Down-regulation
CMGC_DYRK_DYRK1_DYRK1A_ST	P04637	TP53	Q13627	DYRK1A	S15	E17K	17	Missense	proximal	2	no	53.550	53.858	PhosphoSitePlus	COSMIC	34.163	Up-regulation
CMGC_DYRK_DYRK1_DYRK1A_ST	P04637	TP53	Q13627	DYRK1A	S15	V10I	10	Missense	distal	-5	no	53.550	53.179	PhosphoSitePlus	COSMIC	34.163	Down-regulation
CMGC_DYRK_DYRK1_DYRK1A_ST	P04637	TP53	Q13627	DYRK1A	S15	P8L	8	Missense	distal	-7	no	53.550	54.552	PhosphoSitePlus	COSMIC	34.163	Up-regulation
CMGC_DYRK_DYRK1_DYRK1A_ST	P04637	TP53	Q13627	DYRK1A	S15	P8S	8	Missense	distal	-7	no	53.550	53.487	PhosphoSitePlus	COSMIC	34.163	Down-regulation
CMGC_DYRK_DYRK1_DYRK1A_ST	P04637	TP53	Q13627	DYRK1A	S15	P13L	13	Missense	proximal	-2	no	53.550	39.822	PhosphoSitePlus	COSMIC	34.163	Down-regulation
CMGC_DYRK_DYRK1_DYRK1A_ST	P04637	TP53	Q13627	DYRK1A	S15	V10G	10	Missense	distal	-5	no	53.550	53.824	PhosphoSitePlus	COSMIC	34.163	Up-regulation
CMGC_DYRK_DYRK1_DYRK1A_ST	P04637	TP53	Q13627	DYRK1A	S15	T18A	18	Missense	distal	3	no	53.550	53.981	PhosphoSitePlus	COSMIC	34.163	Up-regulation
CMGC_DYRK_DYRK1_DYRK1A_ST	P04637	TP53	Q13627	DYRK1A	S15	F19S	19	Missense	distal	4	no	53.550	50.898	PhosphoSitePlus	COSMIC	34.163	Down-regulation
CMGC_DYRK_DYRK1_DYRK1A_ST	P04637	TP53	Q13627	DYRK1A	S15	E17V	17	Missense	proximal	2	no	53.550	52.482	PhosphoSitePlus	COSMIC	34.163	Down-regulation
CMGC_DYRK_DYRK1_DYRK1A_ST	P04637	TP53	Q13627	DYRK1A	S15	S9G	9	Missense	distal	-6	no	53.550	53.173	PhosphoSitePlus	COSMIC	34.163	Down-regulation
CMGC_DYRK_DYRK1_DYRK1A_ST	P04637	TP53	Q13627	DYRK1A	S15	T18I	18	Missense	distal	3	no	53.550	53.714	PhosphoSitePlus	COSMIC	34.163	Up-regulation
CMGC_DYRK_DYRK1_DYRK1A_ST	P04637	TP53	Q13627	DYRK1A	S15	T18K	18	Missense	distal	3	no	53.550	53.850	PhosphoSitePlus	COSMIC	34.163	Up-regulation
CMGC_DYRK_DYRK1_DYRK1A_ST	P04637	TP53	Q13627	DYRK1A	S15	T18R	18	Missense	distal	3	no	53.550	53.893	PhosphoSitePlus	COSMIC	34.163	Up-regulation
CMGC_DYRK_DYRK1_DYRK1A_ST	P04637	TP53	Q13627	DYRK1A	S15	S15I	15	Missense	central	0	yes	53.550	0.000	PhosphoSitePlus	COSMIC	34.163	Loss
CMGC_DYRK_DYRK1_DYRK1A_ST	P04637	TP53	Q13627	DYRK1A	S33	M40I	40	Missense	distal	7	no	34.790	34.427	EPSD	COSMIC	34.163	Down-regulation
CMGC_DYRK_DYRK1_DYRK1A_ST	P04637	TP53	Q13627	DYRK1A	S33	V31I	31	Missense	proximal	-2	no	34.790	31.591	EPSD	COSMIC;GDSC;CCLE	34.163	Loss
CMGC_DYRK_DYRK1_DYRK1A_ST	P04637	TP53	Q13627	DYRK1A	S33	P36L	36	Missense	distal	3	no	34.790	34.796	EPSD	COSMIC;GDSC;CCLE	34.163	Up-regulation
CMGC_DYRK_DYRK1_DYRK1A_ST	P04637	TP53	Q13627	DYRK1A	S33	L35F	35	Missense	proximal	2	no	34.790	33.804	EPSD	COSMIC	34.163	Loss
CMGC_DYRK_DYRK1_DYRK1A_ST	P04637	TP53	Q13627	DYRK1A	S33	Q38L	38	Missense	distal	5	no	34.790	31.279	EPSD	COSMIC	34.163	Loss
CMGC_DYRK_DYRK1_DYRK1A_ST	P04637	TP53	Q13627	DYRK1A	S33	S37T	37	Missense	distal	4	no	34.790	35.465	EPSD	COSMIC	34.163	Up-regulation
CMGC_DYRK_DYRK1_DYRK1A_ST	P04637	TP53	Q13627	DYRK1A	S33	L26P	26	Missense	distal	-7	no	34.790	33.788	EPSD	COSMIC	34.163	Loss
CMGC_DYRK_DYRK1_DYRK1A_ST	P04637	TP53	Q13627	DYRK1A	S33	P36S	36	Missense	distal	3	no	34.790	35.312	EPSD	COSMIC;GDSC;CCLE	34.163	Up-regulation
CMGC_DYRK_DYRK1_DYRK1A_ST	P04637	TP53	Q13627	DYRK1A	S33	A39V	39	Missense	distal	6	no	34.790	34.863	EPSD	COSMIC	34.163	Up-regulation
CMGC_DYRK_DYRK1_DYRK1A_ST	P04637	TP53	Q13627	DYRK1A	S33	A39S	39	Missense	distal	6	no	34.790	34.757	EPSD	COSMIC	34.163	Down-regulation
CMGC_DYRK_DYRK1_DYRK1A_ST	P04637	TP53	Q13627	DYRK1A	S33	N30K	30	Missense	distal	-3	no	34.790	53.498	EPSD	COSMIC	34.163	Up-regulation
CMGC_DYRK_DYRK1_DYRK1A_ST	P04637	TP53	Q13627	DYRK1A	S33	A39T	39	Missense	distal	6	no	34.790	34.745	EPSD	COSMIC	34.163	Down-regulation
CMGC_DYRK_DYRK1_DYRK1A_ST	P04637	TP53	Q13627	DYRK1A	S33	P27T	27	Missense	distal	-6	no	34.790	35.138	EPSD	COSMIC	34.163	Up-regulation
CMGC_DYRK_DYRK1_DYRK1A_ST	P04637	TP53	Q13627	DYRK1A	S33	P36R	36	Missense	distal	3	no	34.790	35.032	EPSD	COSMIC	34.163	Up-regulation
CMGC_DYRK_DYRK1_DYRK1A_ST	P04637	TP53	Q13627	DYRK1A	S33	L35R	35	Missense	proximal	2	no	34.790	35.690	EPSD	COSMIC	34.163	Up-regulation
CMGC_DYRK_DYRK1_DYRK1A_ST	P04637	TP53	Q13627	DYRK1A	S33	L35H	35	Missense	proximal	2	no	34.790	34.569	EPSD	COSMIC	34.163	Down-regulation
CMGC_DYRK_DYRK1_DYRK1A_ST	P04637	TP53	Q13627	DYRK1A	S33	L35P	35	Missense	proximal	2	no	34.790	35.291	EPSD	COSMIC	34.163	Up-regulation
CMGC_DYRK_DYRK1_DYRK1A_ST	P04637	TP53	Q13627	DYRK1A	S33	L35I	35	Missense	proximal	2	no	34.790	34.052	EPSD	COSMIC	34.163	Loss
CMGC_DYRK_DYRK1_DYRK1A_ST	P04637	TP53	Q13627	DYRK1A	S33	L35V	35	Missense	proximal	2	no	34.790	34.321	EPSD	COSMIC	34.163	Down-regulation
CMGC_DYRK_DYRK1_DYRK1A_ST	P04637	TP53	Q13627	DYRK1A	S46	M44I	44	Missense	proximal	-2	no	22.127	34.517	EPSD	COSMIC	34.163	Gain
CMGC_DYRK_DYRK1_DYRK1A_ST	P04637	TP53	Q13627	DYRK1A	S46	M44R	44	Missense	proximal	-2	no	22.127	42.303	EPSD	COSMIC	34.163	Gain
CMGC_DYRK_DYRK1_DYRK1A_ST	P04637	TP53	Q13627	DYRK1A	S46	M44V	44	Missense	proximal	-2	no	22.127	37.715	EPSD	COSMIC	34.163	Gain
CMGC_DYRK_DYRK1_DYRK1A_ST	P04637	TP53	Q13627	DYRK1A	S46	M44T	44	Missense	proximal	-2	no	22.127	38.277	EPSD	COSMIC	34.163	Gain
CMGC_DYRK_DYRK1_DYRK1A_ST	P04637	TP53	Q13627	DYRK1A	T81	P77A	77	Missense	distal	-4	no	42.596	42.604	EPSD	COSMIC	34.163	Up-regulation
CMGC_DYRK_DYRK1_DYRK1A_ST	P04637	TP53	Q13627	DYRK1A	T81	A76T	76	Missense	distal	-5	no	42.596	42.588	EPSD	COSMIC	34.163	Down-regulation
CMGC_DYRK_DYRK1_DYRK1A_ST	P04637	TP53	Q13627	DYRK1A	T81	A83T	83	Missense	proximal	2	no	42.596	42.036	EPSD	COSMIC	34.163	Down-regulation
CMGC_DYRK_DYRK1_DYRK1A_ST	P04637	TP53	Q13627	DYRK1A	T81	T81I	81	Missense	central	0	yes	42.596	0.000	EPSD	COSMIC	34.163	Loss
CMGC_DYRK_DYRK1_DYRK1A_ST	P04637	TP53	Q13627	DYRK1A	T81	A84V	84	Missense	distal	3	no	42.596	42.194	EPSD	COSMIC	34.163	Down-regulation
CMGC_DYRK_DYRK1_DYRK1A_ST	P04637	TP53	Q13627	DYRK1A	T81	P80L	80	Missense	proximal	-1	no	42.596	42.820	EPSD	COSMIC	34.163	Up-regulation
CMGC_DYRK_DYRK1_DYRK1A_ST	P04637	TP53	Q13627	DYRK1A	T81	A86V	86	Missense	distal	5	no	42.596	39.322	EPSD	COSMIC	34.163	Down-regulation
CMGC_DYRK_DYRK1_DYRK1A_ST	P04637	TP53	Q13627	DYRK1A	T81	P85S	85	Missense	distal	4	no	42.596	42.793	EPSD	COSMIC	34.163	Up-regulation
CMGC_DYRK_DYRK1_DYRK1A_ST	P04637	TP53	Q13627	DYRK1A	T81	A79T	79	Missense	proximal	-2	no	42.596	41.250	EPSD	COSMIC	34.163	Down-regulation
CMGC_DYRK_DYRK1_DYRK1A_ST	P04637	TP53	Q13627	DYRK1A	T81	A84G	84	Missense	distal	3	no	42.596	42.526	EPSD	COSMIC	34.163	Down-regulation
CMGC_DYRK_DYRK1_DYRK1A_ST	P04637	TP53	Q13627	DYRK1A	T81	A78V	78	Missense	distal	-3	no	42.596	47.741	EPSD	COSMIC	34.163	Up-regulation
CMGC_DYRK_DYRK1_DYRK1A_ST	P04637	TP53	Q13627	DYRK1A	T81	A78S	78	Missense	distal	-3	no	42.596	48.423	EPSD	COSMIC	34.163	Up-regulation
CMGC_DYRK_DYRK1_DYRK1A_ST	P04637	TP53	Q13627	DYRK1A	T81	P87L	87	Missense	distal	6	no	42.596	42.668	EPSD	COSMIC	34.163	Up-regulation
CMGC_DYRK_DYRK1_DYRK1A_ST	P04637	TP53	Q13627	DYRK1A	T81	P85L	85	Missense	distal	4	no	42.596	44.643	EPSD	COSMIC	34.163	Up-regulation
CMGC_DYRK_DYRK1_DYRK1A_ST	P04637	TP53	Q13627	DYRK1A	T81	P82S	82	Missense	proximal	1	no	42.596	20.643	EPSD	COSMIC	34.163	Loss
CMGC_DYRK_DYRK1_DYRK1A_ST	P04637	TP53	Q13627	DYRK1A	T81	P77S	77	Missense	distal	-4	no	42.596	42.598	EPSD	COSMIC	34.163	Up-regulation
CMGC_DYRK_DYRK1_DYRK1A_ST	P04637	TP53	Q13627	DYRK1A	T81	P80S	80	Missense	proximal	-1	no	42.596	42.417	EPSD	COSMIC	34.163	Down-regulation
CMGC_DYRK_DYRK1_DYRK1A_ST	P04637	TP53	Q13627	DYRK1A	T81	A84T	84	Missense	distal	3	no	42.596	42.165	EPSD	COSMIC	34.163	Down-regulation
CMGC_DYRK_DYRK1_DYRK1A_ST	P04637	TP53	Q13627	DYRK1A	T81	A83E	83	Missense	proximal	2	no	42.596	42.494	EPSD	COSMIC	34.163	Down-regulation
CMGC_DYRK_DYRK1_DYRK1A_ST	P04637	TP53	Q13627	DYRK1A	T81	P85T	85	Missense	distal	4	no	42.596	43.468	EPSD	COSMIC	34.163	Up-regulation
CMGC_DYRK_DYRK1_DYRK1A_ST	P04637	TP53	Q13627	DYRK1A	T81	A74V	74	Missense	distal	-7	no	42.596	43.413	EPSD	COSMIC	34.163	Up-regulation
CMGC_DYRK_DYRK1_DYRK1A_ST	P04637	TP53	Q13627	DYRK1A	T81	P75S	75	Missense	distal	-6	no	42.596	43.300	EPSD	COSMIC	34.163	Up-regulation
CMGC_DYRK_DYRK1_DYRK1A_ST	P04637	TP53	Q13627	DYRK1A	T81	A76V	76	Missense	distal	-5	no	42.596	43.028	EPSD	COSMIC	34.163	Up-regulation
CMGC_DYRK_DYRK1_DYRK1A_ST	P04637	TP53	Q13627	DYRK1A	T81	P75R	75	Missense	distal	-6	no	42.596	43.014	EPSD	COSMIC	34.163	Up-regulation
CMGC_DYRK_DYRK1_DYRK1A_ST	P04637	TP53	Q13627	DYRK1A	T81	P87H	87	Missense	distal	6	no	42.596	42.673	EPSD	COSMIC	34.163	Up-regulation
CMGC_DYRK_DYRK1_DYRK1A_ST	P04637	TP53	Q13627	DYRK1A	T81	P87T	87	Missense	distal	6	no	42.596	42.593	EPSD	COSMIC	34.163	Down-regulation
CMGC_DYRK_DYRK1_DYRK1A_ST	P04637	TP53	Q13627	DYRK1A	T81	P87S	87	Missense	distal	6	no	42.596	42.606	EPSD	COSMIC	34.163	Up-regulation
CMGC_DYRK_DYRK1_DYRK1A_ST	P04637	TP53	Q13627	DYRK1A	T81	P87R	87	Missense	distal	6	no	42.596	42.544	EPSD	COSMIC	34.163	Down-regulation
CMGC_DYRK_DYRK1_DYRK1A_ST	P04637	TP53	Q13627	DYRK1A	T81	P87C	87	Missense	distal	6	no	42.596	42.690	EPSD	COSMIC	34.163	Up-regulation
CMGC_DYRK_DYRK1_DYRK1A_ST	P04637	TP53	Q13627	DYRK1A	T81	A86E	86	Missense	distal	5	no	42.596	44.491	EPSD	COSMIC	34.163	Up-regulation
CMGC_DYRK_DYRK1_DYRK1A_ST	P04637	TP53	Q13627	DYRK1A	T81	A86S	86	Missense	distal	5	no	42.596	42.974	EPSD	COSMIC	34.163	Up-regulation
CMGC_DYRK_DYRK1_DYRK1A_ST	P04637	TP53	Q13627	DYRK1A	T81	A83V	83	Missense	proximal	2	no	42.596	41.426	EPSD	COSMIC	34.163	Down-regulation
CMGC_DYRK_DYRK1_DYRK1A_ST	P04637	TP53	Q13627	DYRK1A	S99	S99F	99	Missense	central	0	yes	36.467	0.000	EPSD	COSMIC	34.163	Loss
CMGC_DYRK_DYRK1_DYRK1A_ST	P04637	TP53	Q13627	DYRK1A	S99	S96F	96	Missense	distal	-3	no	36.467	17.294	EPSD	COSMIC	34.163	Loss
CMGC_DYRK_DYRK1_DYRK1A_ST	P04637	TP53	Q13627	DYRK1A	S99	P98S	98	Missense	proximal	-1	no	36.467	36.287	EPSD	COSMIC;CCLE	34.163	Down-regulation
CMGC_DYRK_DYRK1_DYRK1A_ST	P04637	TP53	Q13627	DYRK1A	S99	T102I	102	Missense	distal	3	no	36.467	36.631	EPSD	COSMIC	34.163	Up-regulation
CMGC_DYRK_DYRK1_DYRK1A_ST	P04637	TP53	Q13627	DYRK1A	S99	S94P	94	Missense	distal	-5	no	36.467	37.221	EPSD	COSMIC	34.163	Up-regulation
CMGC_DYRK_DYRK1_DYRK1A_ST	P04637	TP53	Q13627	DYRK1A	S99	K101R	101	Missense	proximal	2	no	36.467	36.459	EPSD	COSMIC	34.163	Down-regulation
CMGC_DYRK_DYRK1_DYRK1A_ST	P04637	TP53	Q13627	DYRK1A	S99	S94T	94	Missense	distal	-5	no	36.467	36.129	EPSD	COSMIC	34.163	Down-regulation
CMGC_DYRK_DYRK1_DYRK1A_ST	P04637	TP53	Q13627	DYRK1A	S99	P98L	98	Missense	proximal	-1	no	36.467	36.690	EPSD	COSMIC;GDSC;CCLE	34.163	Up-regulation
CMGC_DYRK_DYRK1_DYRK1A_ST	P04637	TP53	Q13627	DYRK1A	S99	S95F	95	Missense	distal	-4	no	36.467	36.442	EPSD	COSMIC;CCLE	34.163	Down-regulation
CMGC_DYRK_DYRK1_DYRK1A_ST	P04637	TP53	Q13627	DYRK1A	S99	S96C	96	Missense	distal	-3	no	36.467	21.552	EPSD	COSMIC	34.163	Loss
CMGC_DYRK_DYRK1_DYRK1A_ST	P04637	TP53	Q13627	DYRK1A	S99	S106I	106	Missense	distal	7	no	36.467	38.760	EPSD	COSMIC	34.163	Up-regulation
CMGC_DYRK_DYRK1_DYRK1A_ST	P04637	TP53	Q13627	DYRK1A	S99	P98F	98	Missense	proximal	-1	no	36.467	38.275	EPSD	COSMIC	34.163	Up-regulation
CMGC_DYRK_DYRK1_DYRK1A_ST	P04637	TP53	Q13627	DYRK1A	S99	T102P	102	Missense	distal	3	no	36.467	36.567	EPSD	COSMIC	34.163	Up-regulation
CMGC_DYRK_DYRK1_DYRK1A_ST	P04637	TP53	Q13627	DYRK1A	S99	S94L	94	Missense	distal	-5	no	36.467	35.785	EPSD	COSMIC	34.163	Down-regulation
CMGC_DYRK_DYRK1_DYRK1A_ST	P04637	TP53	Q13627	DYRK1A	S99	S96P	96	Missense	distal	-3	no	36.467	33.695	EPSD	COSMIC	34.163	Loss
CMGC_DYRK_DYRK1_DYRK1A_ST	P04637	TP53	Q13627	DYRK1A	S99	P98T	98	Missense	proximal	-1	no	36.467	35.817	EPSD	COSMIC	34.163	Down-regulation
CMGC_DYRK_DYRK1_DYRK1A_ST	P04637	TP53	Q13627	DYRK1A	S99	S96Y	96	Missense	distal	-3	no	36.467	27.069	EPSD	COSMIC	34.163	Loss
CMGC_DYRK_DYRK1_DYRK1A_ST	P04637	TP53	Q13627	DYRK1A	S99	S99P	99	Missense	central	0	yes	36.467	0.000	EPSD	COSMIC	34.163	Loss
CMGC_DYRK_DYRK1_DYRK1A_ST	P04637	TP53	Q13627	DYRK1A	S99	V97I	97	Missense	proximal	-2	no	36.467	33.268	EPSD	COSMIC	34.163	Loss
CMGC_DYRK_DYRK1_DYRK1A_ST	P04637	TP53	Q13627	DYRK1A	S99	Q104H	104	Missense	distal	5	no	36.467	29.683	EPSD	COSMIC	34.163	Loss
CMGC_DYRK_DYRK1_DYRK1A_ST	P04637	TP53	Q13627	DYRK1A	S99	L93M	93	Missense	distal	-6	no	36.467	35.659	EPSD	COSMIC	34.163	Down-regulation
CMGC_DYRK_DYRK1_DYRK1A_ST	P04637	TP53	Q13627	DYRK1A	S99	K101N	101	Missense	proximal	2	no	36.467	34.879	EPSD	COSMIC	34.163	Down-regulation
CMGC_DYRK_DYRK1_DYRK1A_ST	P04637	TP53	Q13627	DYRK1A	S99	V97A	97	Missense	proximal	-2	no	36.467	38.375	EPSD	COSMIC	34.163	Up-regulation
CMGC_DYRK_DYRK1_DYRK1A_ST	P04637	TP53	Q13627	DYRK1A	S99	P92A	92	Missense	distal	-7	no	36.467	36.782	EPSD	COSMIC	34.163	Up-regulation
CMGC_DYRK_DYRK1_DYRK1A_ST	P04637	TP53	Q13627	DYRK1A	S99	Q104L	104	Missense	distal	5	no	36.467	32.955	EPSD	COSMIC	34.163	Loss
CMGC_DYRK_DYRK1_DYRK1A_ST	P04637	TP53	Q13627	DYRK1A	S99	P92L	92	Missense	distal	-7	no	36.467	37.469	EPSD	COSMIC	34.163	Up-regulation
CMGC_DYRK_DYRK1_DYRK1A_ST	P04637	TP53	Q13627	DYRK1A	S99	L93P	93	Missense	distal	-6	no	36.467	36.409	EPSD	COSMIC	34.163	Down-regulation
CMGC_DYRK_DYRK1_DYRK1A_ST	P04637	TP53	Q13627	DYRK1A	S99	L93F	93	Missense	distal	-6	no	36.467	35.603	EPSD	COSMIC	34.163	Down-regulation
CMGC_DYRK_DYRK1_DYRK1A_ST	P04637	TP53	Q13627	DYRK1A	S99	L93H	93	Missense	distal	-6	no	36.467	36.210	EPSD	COSMIC	34.163	Down-regulation
CMGC_DYRK_DYRK1_DYRK1A_ST	P04637	TP53	Q13627	DYRK1A	S99	S95Y	95	Missense	distal	-4	no	36.467	36.437	EPSD	COSMIC	34.163	Down-regulation
CMGC_DYRK_DYRK1_DYRK1A_ST	P04637	TP53	Q13627	DYRK1A	S127	C124W	124	Missense	distal	-3	no	37.482	36.171	EPSD	COSMIC	34.163	Down-regulation
CMGC_DYRK_DYRK1_DYRK1A_ST	P04637	TP53	Q13627	DYRK1A	S127	C124F	124	Missense	distal	-3	no	37.482	33.224	EPSD	COSMIC	34.163	Loss
CMGC_DYRK_DYRK1_DYRK1A_ST	P04637	TP53	Q13627	DYRK1A	S127	C124S	124	Missense	distal	-3	no	37.482	52.397	EPSD	COSMIC	34.163	Up-regulation
CMGC_DYRK_DYRK1_DYRK1A_ST	P04637	TP53	Q13627	DYRK1A	S127	S127A	127	Missense	central	0	yes	37.482	0.000	EPSD	COSMIC	34.163	Loss
CMGC_DYRK_DYRK1_DYRK1A_ST	P04637	TP53	Q13627	DYRK1A	S127	S127L	127	Missense	central	0	yes	37.482	0.000	EPSD	COSMIC	34.163	Loss
CMGC_DYRK_DYRK1_DYRK1A_ST	P04637	TP53	Q13627	DYRK1A	S127	C124T	124	Missense	distal	-3	no	37.482	43.378	EPSD	COSMIC	34.163	Up-regulation
CMGC_DYRK_DYRK1_DYRK1A_ST	P04637	TP53	Q13627	DYRK1A	S127	S127I	127	Missense	central	0	yes	37.482	0.000	EPSD	COSMIC	34.163	Loss
CMGC_DYRK_DYRK1_DYRK1A_ST	P04637	TP53	Q13627	DYRK1A	S127	S127G	127	Missense	central	0	yes	37.482	0.000	EPSD	COSMIC	34.163	Loss
CMGC_DYRK_DYRK1_DYRK1A_ST	P04637	TP53	Q13627	DYRK1A	S127	N131H	131	Missense	distal	4	no	37.482	36.400	EPSD	COSMIC	34.163	Down-regulation
CMGC_DYRK_DYRK1_DYRK1A_ST	P04637	TP53	Q13627	DYRK1A	S127	N131D	131	Missense	distal	4	no	37.482	37.817	EPSD	COSMIC	34.163	Up-regulation
CMGC_DYRK_DYRK1_DYRK1A_ST	P04637	TP53	Q13627	DYRK1A	S127	T125I	125	Missense	proximal	-2	no	37.482	33.722	EPSD	COSMIC	34.163	Loss
CMGC_DYRK_DYRK1_DYRK1A_ST	P04637	TP53	Q13627	DYRK1A	S127	F134I	134	Missense	distal	7	no	37.482	36.378	EPSD	COSMIC	34.163	Down-regulation
CMGC_DYRK_DYRK1_DYRK1A_ST	P04637	TP53	Q13627	DYRK1A	S127	K120T	120	Missense	distal	-7	no	37.482	37.333	EPSD	COSMIC	34.163	Down-regulation
CMGC_DYRK_DYRK1_DYRK1A_ST	P04637	TP53	Q13627	DYRK1A	S127	F134S	134	Missense	distal	7	no	37.482	34.085	EPSD	COSMIC	34.163	Loss
CMGC_DYRK_DYRK1_DYRK1A_ST	P04637	TP53	Q13627	DYRK1A	S127	T125K	125	Missense	proximal	-2	no	37.482	37.075	EPSD	COSMIC	34.163	Down-regulation
CMGC_DYRK_DYRK1_DYRK1A_ST	P04637	TP53	Q13627	DYRK1A	S127	M133I	133	Missense	distal	6	no	37.482	37.498	EPSD	COSMIC	34.163	Up-regulation
CMGC_DYRK_DYRK1_DYRK1A_ST	P04637	TP53	Q13627	DYRK1A	S127	N131K	131	Missense	distal	4	no	37.482	37.202	EPSD	COSMIC;CCLE	34.163	Down-regulation
CMGC_DYRK_DYRK1_DYRK1A_ST	P04637	TP53	Q13627	DYRK1A	S127	P128S	128	Missense	proximal	1	no	37.482	15.529	EPSD	COSMIC	34.163	Loss
CMGC_DYRK_DYRK1_DYRK1A_ST	P04637	TP53	Q13627	DYRK1A	S127	M133L	133	Missense	distal	6	no	37.482	37.391	EPSD	COSMIC	34.163	Down-regulation
CMGC_DYRK_DYRK1_DYRK1A_ST	P04637	TP53	Q13627	DYRK1A	S127	A129T	129	Missense	proximal	2	no	37.482	36.921	EPSD	COSMIC	34.163	Down-regulation
CMGC_DYRK_DYRK1_DYRK1A_ST	P04637	TP53	Q13627	DYRK1A	S127	T123I	123	Missense	distal	-4	no	37.482	37.429	EPSD	COSMIC	34.163	Down-regulation
CMGC_DYRK_DYRK1_DYRK1A_ST	P04637	TP53	Q13627	DYRK1A	S127	A129G	129	Missense	proximal	2	no	37.482	37.640	EPSD	COSMIC	34.163	Up-regulation
CMGC_DYRK_DYRK1_DYRK1A_ST	P04637	TP53	Q13627	DYRK1A	S127	K132W	132	Missense	distal	5	no	37.482	33.724	EPSD	COSMIC	34.163	Loss
CMGC_DYRK_DYRK1_DYRK1A_ST	P04637	TP53	Q13627	DYRK1A	S127	A129V	129	Missense	proximal	2	no	37.482	36.311	EPSD	COSMIC	34.163	Down-regulation
CMGC_DYRK_DYRK1_DYRK1A_ST	P04637	TP53	Q13627	DYRK1A	S127	P128A	128	Missense	proximal	1	no	37.482	7.337	EPSD	COSMIC	34.163	Loss
CMGC_DYRK_DYRK1_DYRK1A_ST	P04637	TP53	Q13627	DYRK1A	S127	L130I	130	Missense	distal	3	no	37.482	37.539	EPSD	COSMIC	34.163	Up-regulation
CMGC_DYRK_DYRK1_DYRK1A_ST	P04637	TP53	Q13627	DYRK1A	S127	S121F	121	Missense	distal	-6	no	37.482	35.972	EPSD	COSMIC	34.163	Down-regulation
CMGC_DYRK_DYRK1_DYRK1A_ST	P04637	TP53	Q13627	DYRK1A	S127	A129D	129	Missense	proximal	2	no	37.482	36.656	EPSD	COSMIC	34.163	Down-regulation
CMGC_DYRK_DYRK1_DYRK1A_ST	P04637	TP53	Q13627	DYRK1A	S127	K120Q	120	Missense	distal	-7	no	37.482	38.030	EPSD	COSMIC	34.163	Up-regulation
CMGC_DYRK_DYRK1_DYRK1A_ST	P04637	TP53	Q13627	DYRK1A	S127	T125S	125	Missense	proximal	-2	no	37.482	37.782	EPSD	COSMIC	34.163	Up-regulation
CMGC_DYRK_DYRK1_DYRK1A_ST	P04637	TP53	Q13627	DYRK1A	S127	P128L	128	Missense	proximal	1	no	37.482	-4.849	EPSD	COSMIC	34.163	Loss
CMGC_DYRK_DYRK1_DYRK1A_ST	P04637	TP53	Q13627	DYRK1A	S127	V122L	122	Missense	distal	-5	no	37.482	36.699	EPSD	COSMIC	34.163	Down-regulation
CMGC_DYRK_DYRK1_DYRK1A_ST	P04637	TP53	Q13627	DYRK1A	S127	C124L	124	Missense	distal	-3	no	37.482	47.632	EPSD	COSMIC	34.163	Up-regulation
CMGC_DYRK_DYRK1_DYRK1A_ST	P04637	TP53	Q13627	DYRK1A	S127	N131T	131	Missense	distal	4	no	37.482	37.151	EPSD	COSMIC	34.163	Down-regulation
CMGC_DYRK_DYRK1_DYRK1A_ST	P04637	TP53	Q13627	DYRK1A	S127	M133V	133	Missense	distal	6	no	37.482	37.435	EPSD	COSMIC	34.163	Down-regulation
CMGC_DYRK_DYRK1_DYRK1A_ST	P04637	TP53	Q13627	DYRK1A	S183	E180G	180	Missense	distal	-3	no	27.070	36.214	EPSD	COSMIC	34.163	Gain
CMGC_DYRK_DYRK1_DYRK1A_ST	P04637	TP53	Q13627	DYRK1A	S183	D184G	184	Missense	proximal	1	no	27.070	35.559	EPSD	COSMIC	34.163	Gain
CMGC_DYRK_DYRK1_DYRK1A_ST	P04637	TP53	Q13627	DYRK1A	T284	D281R	281	Missense	distal	-3	no	24.464	39.820	EPSD	COSMIC	34.163	Gain
CMGC_DYRK_DYRK1_DYRK1A_ST	P04637	TP53	Q13627	DYRK1A	T304	S303C	303	Missense	proximal	-1	no	36.536	37.976	EPSD	COSMIC	34.163	Up-regulation
CMGC_DYRK_DYRK1_DYRK1A_ST	P04637	TP53	Q13627	DYRK1A	T304	S303F	303	Missense	proximal	-1	no	36.536	38.524	EPSD	COSMIC	34.163	Up-regulation
CMGC_DYRK_DYRK1_DYRK1A_ST	P04637	TP53	Q13627	DYRK1A	T304	P301L	301	Missense	distal	-3	no	36.536	34.543	EPSD	COSMIC	34.163	Down-regulation
CMGC_DYRK_DYRK1_DYRK1A_ST	P04637	TP53	Q13627	DYRK1A	T304	K305T	305	Missense	proximal	1	no	36.536	27.754	EPSD	COSMIC	34.163	Loss
CMGC_DYRK_DYRK1_DYRK1A_ST	P04637	TP53	Q13627	DYRK1A	T304	P300L	300	Missense	distal	-4	no	36.536	36.533	EPSD	COSMIC	34.163	Down-regulation
CMGC_DYRK_DYRK1_DYRK1A_ST	P04637	TP53	Q13627	DYRK1A	T304	N310T	310	Missense	distal	6	no	36.536	36.523	EPSD	COSMIC	34.163	Down-regulation
CMGC_DYRK_DYRK1_DYRK1A_ST	P04637	TP53	Q13627	DYRK1A	T304	T304N	304	Missense	central	0	yes	36.536	0.000	EPSD	COSMIC	34.163	Loss
CMGC_DYRK_DYRK1_DYRK1A_ST	P04637	TP53	Q13627	DYRK1A	T304	H297P	297	Missense	distal	-7	no	36.536	36.426	EPSD	COSMIC	34.163	Down-regulation
CMGC_DYRK_DYRK1_DYRK1A_ST	P04637	TP53	Q13627	DYRK1A	T304	P309S	309	Missense	distal	5	no	36.536	36.597	EPSD	COSMIC;GDSC;CCLE	34.163	Up-regulation
CMGC_DYRK_DYRK1_DYRK1A_ST	P04637	TP53	Q13627	DYRK1A	T304	G302E	302	Missense	proximal	-2	no	36.536	39.042	EPSD	COSMIC	34.163	Up-regulation
CMGC_DYRK_DYRK1_DYRK1A_ST	P04637	TP53	Q13627	DYRK1A	T304	N310L	310	Missense	distal	6	no	36.536	36.598	EPSD	COSMIC	34.163	Up-regulation
CMGC_DYRK_DYRK1_DYRK1A_ST	P04637	TP53	Q13627	DYRK1A	T304	K305N	305	Missense	proximal	1	no	36.536	-15.946	EPSD	COSMIC	34.163	Loss
CMGC_DYRK_DYRK1_DYRK1A_ST	P04637	TP53	Q13627	DYRK1A	T304	H297Y	297	Missense	distal	-7	no	36.536	37.906	EPSD	COSMIC	34.163	Up-regulation
CMGC_DYRK_DYRK1_DYRK1A_ST	P04637	TP53	Q13627	DYRK1A	T304	P300S	300	Missense	distal	-4	no	36.536	36.537	EPSD	COSMIC	34.163	Up-regulation
CMGC_DYRK_DYRK1_DYRK1A_ST	P04637	TP53	Q13627	DYRK1A	T304	S303N	303	Missense	proximal	-1	no	36.536	37.395	EPSD	COSMIC	34.163	Up-regulation
CMGC_DYRK_DYRK1_DYRK1A_ST	P04637	TP53	Q13627	DYRK1A	T304	N311Y	311	Missense	distal	7	no	36.536	36.350	EPSD	COSMIC	34.163	Down-regulation
CMGC_DYRK_DYRK1_DYRK1A_ST	P04637	TP53	Q13627	DYRK1A	T304	T304A	304	Missense	central	0	yes	36.536	0.000	EPSD	COSMIC	34.163	Loss
CMGC_DYRK_DYRK1_DYRK1A_ST	P04637	TP53	Q13627	DYRK1A	T304	L299P	299	Missense	distal	-5	no	36.536	37.972	EPSD	COSMIC	34.163	Up-regulation
CMGC_DYRK_DYRK1_DYRK1A_ST	P04637	TP53	Q13627	DYRK1A	T304	R306P	306	Missense	proximal	2	no	36.536	36.136	EPSD	COSMIC	34.163	Down-regulation
CMGC_DYRK_DYRK1_DYRK1A_ST	P04637	TP53	Q13627	DYRK1A	T304	A307T	307	Missense	distal	3	no	36.536	36.105	EPSD	COSMIC	34.163	Down-regulation
CMGC_DYRK_DYRK1_DYRK1A_ST	P04637	TP53	Q13627	DYRK1A	T304	N311K	311	Missense	distal	7	no	36.536	35.395	EPSD	COSMIC	34.163	Down-regulation
CMGC_DYRK_DYRK1_DYRK1A_ST	P04637	TP53	Q13627	DYRK1A	T304	P300R	300	Missense	distal	-4	no	36.536	36.551	EPSD	COSMIC	34.163	Up-regulation
CMGC_DYRK_DYRK1_DYRK1A_ST	P04637	TP53	Q13627	DYRK1A	T304	K305E	305	Missense	proximal	1	no	36.536	31.125	EPSD	COSMIC	34.163	Loss
CMGC_DYRK_DYRK1_DYRK1A_ST	P04637	TP53	Q13627	DYRK1A	T304	P301S	301	Missense	distal	-3	no	36.536	39.308	EPSD	COSMIC	34.163	Up-regulation
CMGC_DYRK_DYRK1_DYRK1A_ST	P04637	TP53	Q13627	DYRK1A	T304	N310H	310	Missense	distal	6	no	36.536	36.603	EPSD	COSMIC	34.163	Up-regulation
CMGC_DYRK_DYRK1_DYRK1A_ST	P04637	TP53	Q13627	DYRK1A	T304	P300A	300	Missense	distal	-4	no	36.536	36.543	EPSD	COSMIC	34.163	Up-regulation
CMGC_DYRK_DYRK1_DYRK1A_ST	P04637	TP53	Q13627	DYRK1A	T304	R306Q	306	Missense	proximal	2	no	36.536	36.346	EPSD	COSMIC	34.163	Down-regulation
CMGC_DYRK_DYRK1_DYRK1A_ST	P04637	TP53	Q13627	DYRK1A	T304	K305R	305	Missense	proximal	1	no	36.536	35.050	EPSD	COSMIC	34.163	Down-regulation
CMGC_DYRK_DYRK1_DYRK1A_ST	P04637	TP53	Q13627	DYRK1A	T304	E298V	298	Missense	distal	-6	no	36.536	35.127	EPSD	COSMIC	34.163	Down-regulation
CMGC_DYRK_DYRK1_DYRK1A_ST	P04637	TP53	Q13627	DYRK1A	T304	L299V	299	Missense	distal	-5	no	36.536	37.319	EPSD	COSMIC	34.163	Up-regulation
CMGC_DYRK_DYRK1_DYRK1A_ST	P04637	TP53	Q13627	DYRK1A	T304	S303T	303	Missense	proximal	-1	no	36.536	36.066	EPSD	COSMIC	34.163	Down-regulation
CMGC_DYRK_DYRK1_DYRK1A_ST	P04637	TP53	Q13627	DYRK1A	T304	L308M	308	Missense	distal	4	no	36.536	35.676	EPSD	COSMIC	34.163	Down-regulation
CMGC_DYRK_DYRK1_DYRK1A_ST	P04637	TP53	Q13627	DYRK1A	T304	N311H	311	Missense	distal	7	no	36.536	35.260	EPSD	COSMIC	34.163	Down-regulation
CMGC_DYRK_DYRK1_DYRK1A_ST	P04637	TP53	Q13627	DYRK1A	T304	L308V	308	Missense	distal	4	no	36.536	37.122	EPSD	COSMIC	34.163	Up-regulation
CMGC_DYRK_DYRK1_DYRK1A_ST	P04637	TP53	Q13627	DYRK1A	T304	E298Q	298	Missense	distal	-6	no	36.536	35.832	EPSD	COSMIC	34.163	Down-regulation
CMGC_DYRK_DYRK1_DYRK1A_ST	P04637	TP53	Q13627	DYRK1A	T304	E298D	298	Missense	distal	-6	no	36.536	35.914	EPSD	COSMIC	34.163	Down-regulation
CMGC_DYRK_DYRK1_DYRK1A_ST	P04637	TP53	Q13627	DYRK1A	T304	T304I	304	Missense	central	0	yes	36.536	0.000	EPSD	COSMIC	34.163	Loss
CMGC_DYRK_DYRK1_DYRK1A_ST	P04637	TP53	Q13627	DYRK1A	T304	E298K	298	Missense	distal	-6	no	36.536	35.998	EPSD	COSMIC	34.163	Down-regulation
CMGC_DYRK_DYRK1_DYRK1A_ST	P04637	TP53	Q13627	DYRK1A	T304	N310D	310	Missense	distal	6	no	36.536	36.616	EPSD	COSMIC	34.163	Up-regulation
CMGC_DYRK_DYRK1_DYRK1A_ST	P04637	TP53	Q13627	DYRK1A	T304	N311D	311	Missense	distal	7	no	36.536	35.447	EPSD	COSMIC	34.163	Down-regulation
CMGC_DYRK_DYRK1_DYRK1A_ST	P04637	TP53	Q13627	DYRK1A	T304	P301A	301	Missense	distal	-3	no	36.536	33.481	EPSD	COSMIC	34.163	Loss
CMGC_DYRK_DYRK1_DYRK1A_ST	P04637	TP53	Q13627	DYRK1A	T304	P301Q	301	Missense	distal	-3	no	36.536	34.146	EPSD	COSMIC	34.163	Loss
CMGC_DYRK_DYRK1_DYRK1A_ST	P04637	TP53	Q13627	DYRK1A	T304	P309R	309	Missense	distal	5	no	36.536	38.171	EPSD	COSMIC	34.163	Up-regulation
CMGC_DYRK_DYRK1_DYRK1A_ST	P04637	TP53	Q13627	DYRK1A	T304	H297N	297	Missense	distal	-7	no	36.536	37.320	EPSD	COSMIC	34.163	Up-regulation
CMGC_DYRK_DYRK1_DYRK1A_ST	P04637	TP53	Q13627	DYRK1A	T304	G302R	302	Missense	proximal	-2	no	36.536	43.230	EPSD	COSMIC	34.163	Up-regulation
CMGC_DYRK_DYRK1_DYRK1A_ST	P04637	TP53	Q13627	DYRK1A	T304	E298A	298	Missense	distal	-6	no	36.536	36.665	EPSD	COSMIC	34.163	Up-regulation
CMGC_DYRK_DYRK1_DYRK1A_ST	P04637	TP53	Q13627	DYRK1A	T304	A307S	307	Missense	distal	3	no	36.536	36.727	EPSD	COSMIC	34.163	Up-regulation
CMGC_DYRK_DYRK1_DYRK1A_ST	P04637	TP53	Q13627	DYRK1A	T304	E298G	298	Missense	distal	-6	no	36.536	36.306	EPSD	COSMIC	34.163	Down-regulation
CMGC_DYRK_DYRK1_DYRK1A_ST	P04637	TP53	Q13627	DYRK1A	S315	N310T	310	Missense	distal	-5	no	40.613	41.647	EPSD	COSMIC	34.163	Up-regulation
CMGC_DYRK_DYRK1_DYRK1A_ST	P04637	TP53	Q13627	DYRK1A	S315	Q317R	317	Missense	proximal	2	no	40.613	40.803	EPSD	COSMIC	34.163	Up-regulation
CMGC_DYRK_DYRK1_DYRK1A_ST	P04637	TP53	Q13627	DYRK1A	S315	P309S	309	Missense	distal	-6	no	40.613	41.316	EPSD	COSMIC;GDSC;CCLE	34.163	Up-regulation
CMGC_DYRK_DYRK1_DYRK1A_ST	P04637	TP53	Q13627	DYRK1A	S315	K319E	319	Missense	distal	4	no	40.613	40.971	EPSD	COSMIC	34.163	Up-regulation
CMGC_DYRK_DYRK1_DYRK1A_ST	P04637	TP53	Q13627	DYRK1A	S315	P322L	322	Missense	distal	7	no	40.613	42.272	EPSD	COSMIC	34.163	Up-regulation
CMGC_DYRK_DYRK1_DYRK1A_ST	P04637	TP53	Q13627	DYRK1A	S315	K320N	320	Missense	distal	5	no	40.613	36.149	EPSD	COSMIC;GDSC;CCLE	34.163	Down-regulation
CMGC_DYRK_DYRK1_DYRK1A_ST	P04637	TP53	Q13627	DYRK1A	S315	N310L	310	Missense	distal	-5	no	40.613	41.303	EPSD	COSMIC	34.163	Up-regulation
CMGC_DYRK_DYRK1_DYRK1A_ST	P04637	TP53	Q13627	DYRK1A	S315	T312S	312	Missense	distal	-3	no	40.613	49.632	EPSD	COSMIC	34.163	Up-regulation
CMGC_DYRK_DYRK1_DYRK1A_ST	P04637	TP53	Q13627	DYRK1A	S315	N311Y	311	Missense	distal	-4	no	40.613	40.579	EPSD	COSMIC	34.163	Down-regulation
CMGC_DYRK_DYRK1_DYRK1A_ST	P04637	TP53	Q13627	DYRK1A	S315	P322R	322	Missense	distal	7	no	40.613	39.138	EPSD	COSMIC	34.163	Down-regulation
CMGC_DYRK_DYRK1_DYRK1A_ST	P04637	TP53	Q13627	DYRK1A	S315	N311K	311	Missense	distal	-4	no	40.613	40.587	EPSD	COSMIC	34.163	Down-regulation
CMGC_DYRK_DYRK1_DYRK1A_ST	P04637	TP53	Q13627	DYRK1A	S315	Q317K	317	Missense	proximal	2	no	40.613	40.810	EPSD	COSMIC	34.163	Up-regulation
CMGC_DYRK_DYRK1_DYRK1A_ST	P04637	TP53	Q13627	DYRK1A	S315	S315P	315	Missense	central	0	yes	40.613	0.000	EPSD	COSMIC	34.163	Loss
CMGC_DYRK_DYRK1_DYRK1A_ST	P04637	TP53	Q13627	DYRK1A	S315	N310H	310	Missense	distal	-5	no	40.613	41.865	EPSD	COSMIC	34.163	Up-regulation
CMGC_DYRK_DYRK1_DYRK1A_ST	P04637	TP53	Q13627	DYRK1A	S315	S314C	314	Missense	proximal	-1	no	40.613	42.053	EPSD	COSMIC	34.163	Up-regulation
CMGC_DYRK_DYRK1_DYRK1A_ST	P04637	TP53	Q13627	DYRK1A	S315	P318A	318	Missense	distal	3	no	40.613	40.944	EPSD	COSMIC	34.163	Up-regulation
CMGC_DYRK_DYRK1_DYRK1A_ST	P04637	TP53	Q13627	DYRK1A	S315	P316L	316	Missense	proximal	1	no	40.613	-1.718	EPSD	COSMIC	34.163	Loss
CMGC_DYRK_DYRK1_DYRK1A_ST	P04637	TP53	Q13627	DYRK1A	S315	L308M	308	Missense	distal	-7	no	40.613	40.853	EPSD	COSMIC	34.163	Up-regulation
CMGC_DYRK_DYRK1_DYRK1A_ST	P04637	TP53	Q13627	DYRK1A	S315	S313C	313	Missense	proximal	-2	no	40.613	31.220	EPSD	COSMIC	34.163	Loss
CMGC_DYRK_DYRK1_DYRK1A_ST	P04637	TP53	Q13627	DYRK1A	S315	N311H	311	Missense	distal	-4	no	40.613	40.607	EPSD	COSMIC	34.163	Down-regulation
CMGC_DYRK_DYRK1_DYRK1A_ST	P04637	TP53	Q13627	DYRK1A	S315	L308V	308	Missense	distal	-7	no	40.613	40.742	EPSD	COSMIC	34.163	Up-regulation
CMGC_DYRK_DYRK1_DYRK1A_ST	P04637	TP53	Q13627	DYRK1A	S315	S314F	314	Missense	proximal	-1	no	40.613	42.602	EPSD	COSMIC	34.163	Up-regulation
CMGC_DYRK_DYRK1_DYRK1A_ST	P04637	TP53	Q13627	DYRK1A	S315	K319R	319	Missense	distal	4	no	40.613	38.737	EPSD	COSMIC	34.163	Down-regulation
CMGC_DYRK_DYRK1_DYRK1A_ST	P04637	TP53	Q13627	DYRK1A	S315	T312A	312	Missense	distal	-3	no	40.613	43.805	EPSD	COSMIC	34.163	Up-regulation
CMGC_DYRK_DYRK1_DYRK1A_ST	P04637	TP53	Q13627	DYRK1A	S315	N310D	310	Missense	distal	-5	no	40.613	41.496	EPSD	COSMIC	34.163	Up-regulation
CMGC_DYRK_DYRK1_DYRK1A_ST	P04637	TP53	Q13627	DYRK1A	S315	N311D	311	Missense	distal	-4	no	40.613	40.609	EPSD	COSMIC	34.163	Down-regulation
CMGC_DYRK_DYRK1_DYRK1A_ST	P04637	TP53	Q13627	DYRK1A	S315	P309R	309	Missense	distal	-6	no	40.613	41.030	EPSD	COSMIC	34.163	Up-regulation
CMGC_DYRK_DYRK1_DYRK1A_ST	P04637	TP53	Q13627	DYRK1A	S315	S313N	313	Missense	proximal	-2	no	40.613	22.920	EPSD	COSMIC	34.163	Loss
CMGC_DYRK_DYRK1_DYRK1A_ST	P04637	TP53	Q13627	DYRK1A	S315	Q317P	317	Missense	proximal	2	no	40.613	40.404	EPSD	COSMIC	34.163	Down-regulation
CMGC_DYRK_DYRK1_DYRK1A_ST	P04637	TP53	Q13627	DYRK1A	S315	P316S	316	Missense	proximal	1	no	40.613	18.660	EPSD	COSMIC	34.163	Loss
CMGC_DYRK_DYRK1_DYRK1A_ST	P04637	TP53	Q13627	DYRK1A	S366	S367F	367	Missense	proximal	1	no	30.331	34.385	EPSD	COSMIC	34.163	Gain
CMGC_DYRK_DYRK1_DYRK1A_ST	P04637	TP53	Q13627	DYRK1A	S376	T377I	377	Missense	proximal	1	no	24.393	36.601	EPSD	COSMIC	34.163	Gain
CMGC_DYRK_DYRK1_DYRK1A_ST	P24385	CCND1	Q13627	DYRK1A	T286	D292G	292	Missense	distal	6	no	45.823	45.676	PhosphoSitePlus	COSMIC	34.163	Down-regulation
CMGC_DYRK_DYRK1_DYRK1A_ST	P24385	CCND1	Q13627	DYRK1A	T286	T286P	286	Missense	central	0	yes	45.823	0.000	PhosphoSitePlus	COSMIC	34.163	Loss
CMGC_DYRK_DYRK1_DYRK1A_ST	P24385	CCND1	Q13627	DYRK1A	T286	A284V	284	Missense	proximal	-2	no	45.823	43.915	PhosphoSitePlus	COSMIC	34.163	Down-regulation
CMGC_DYRK_DYRK1_DYRK1A_ST	P24385	CCND1	Q13627	DYRK1A	T286	E280V	280	Missense	distal	-6	no	45.823	44.414	PhosphoSitePlus	COSMIC;CCLE	34.163	Down-regulation
CMGC_DYRK_DYRK1_DYRK1A_ST	P24385	CCND1	Q13627	DYRK1A	T286	R291W	291	Missense	distal	5	no	45.823	42.021	PhosphoSitePlus	COSMIC;GDSC;CCLE	34.163	Down-regulation
CMGC_DYRK_DYRK1_DYRK1A_ST	P24385	CCND1	Q13627	DYRK1A	T286	R291L	291	Missense	distal	5	no	45.823	43.303	PhosphoSitePlus	COSMIC;GDSC;CCLE	34.163	Down-regulation
CMGC_DYRK_DYRK1_DYRK1A_ST	P24385	CCND1	Q13627	DYRK1A	T286	V290G	290	Missense	distal	4	no	45.823	43.320	PhosphoSitePlus	COSMIC	34.163	Down-regulation
CMGC_DYRK_DYRK1_DYRK1A_ST	Q12778	FOXO1	Q13627	DYRK1A	T24	W25R	25	Missense	proximal	1	no	21.227	37.992	EPSD	COSMIC	34.163	Gain
CMGC_DYRK_DYRK1_DYRK1A_ST	Q12778	FOXO1	Q13627	DYRK1A	S249	G243S	243	Missense	distal	-6	no	44.475	44.851	EPSD	COSMIC	34.163	Up-regulation
CMGC_DYRK_DYRK1_DYRK1A_ST	Q12778	FOXO1	Q13627	DYRK1A	S249	G243V	243	Missense	distal	-6	no	44.475	43.296	EPSD	COSMIC	34.163	Down-regulation
CMGC_DYRK_DYRK1_DYRK1A_ST	Q12778	FOXO1	Q13627	DYRK1A	S287	S287N	287	Missense	central	0	yes	36.170	0.000	EPSD	COSMIC	34.163	Loss
CMGC_DYRK_DYRK1_DYRK1A_ST	Q12778	FOXO1	Q13627	DYRK1A	S293	S287N	287	Missense	distal	-6	no	35.996	34.882	EPSD	COSMIC	34.163	Down-regulation
CMGC_DYRK_DYRK1_DYRK1A_ST	Q12778	FOXO1	Q13627	DYRK1A	S298	H302Y	302	Missense	distal	4	no	42.421	44.134	EPSD	COSMIC	34.163	Up-regulation
CMGC_DYRK_DYRK1_DYRK1A_ST	Q12778	FOXO1	Q13627	DYRK1A	S394	S393Y	393	Missense	proximal	-1	no	33.675	35.440	EPSD	COSMIC	34.163	Gain
CMGC_DYRK_DYRK1_DYRK1A_ST	Q12778	FOXO1	Q13627	DYRK1A	S470	D469A	469	Missense	proximal	-1	no	37.884	37.126	EPSD	COSMIC	34.163	Down-regulation
CMGC_DYRK_DYRK1_DYRK1A_ST	Q12778	FOXO1	Q13627	DYRK1A	S470	K463N	463	Missense	distal	-7	no	37.884	38.913	EPSD	COSMIC	34.163	Up-regulation
CMGC_DYRK_DYRK1_DYRK1A_ST	Q12778	FOXO1	Q13627	DYRK1A	S470	N474D	474	Missense	distal	4	no	37.884	38.219	EPSD	COSMIC	34.163	Up-regulation
CMGC_DYRK_DYRK1_DYRK1A_ST	O76039	CDKL5	Q13627	DYRK1A	S308	A311T	311	Missense	distal	3	no	54.170	53.739	PhosphoSitePlus	COSMIC;GDSC;CCLE	34.163	Down-regulation
CMGC_DYRK_DYRK1_DYRK1A_ST	O76039	CDKL5	Q13627	DYRK1A	S308	R305H	305	Missense	distal	-3	no	54.170	38.838	PhosphoSitePlus	COSMIC	34.163	Down-regulation
CMGC_DYRK_DYRK1_DYRK1A_ST	O76039	CDKL5	Q13627	DYRK1A	S308	R309K	309	Missense	proximal	1	no	54.170	55.655	PhosphoSitePlus	COSMIC	34.163	Up-regulation
CMGC_DYRK_DYRK1_DYRK1A_ST	O76039	CDKL5	Q13627	DYRK1A	S343	L349R	349	Missense	distal	6	no	34.654	34.530	EPSD	COSMIC	34.163	Down-regulation
CMGC_DYRK_DYRK1_DYRK1A_ST	O76039	CDKL5	Q13627	DYRK1A	S377	A374T	374	Missense	distal	-3	no	37.916	34.723	EPSD	COSMIC;GDSC;CCLE	34.163	Down-regulation
CMGC_DYRK_DYRK1_DYRK1A_ST	O76039	CDKL5	Q13627	DYRK1A	S377	A374S	374	Missense	distal	-3	no	37.916	43.743	EPSD	COSMIC	34.163	Up-regulation
CMGC_DYRK_DYRK1_DYRK1A_ST	O76039	CDKL5	Q13627	DYRK1A	S468	S465R	465	Missense	distal	-3	no	26.584	35.174	EPSD	COSMIC	34.163	Gain
CMGC_DYRK_DYRK1_DYRK1A_ST	O76039	CDKL5	Q13627	DYRK1A	S479	P480S	480	Missense	proximal	1	no	41.618	19.665	EPSD	COSMIC	34.163	Loss
CMGC_DYRK_DYRK1_DYRK1A_ST	O76039	CDKL5	Q13627	DYRK1A	S479	S479R	479	Missense	central	0	yes	41.618	0.000	EPSD	COSMIC	34.163	Loss
CMGC_DYRK_DYRK1_DYRK1A_ST	O76039	CDKL5	Q13627	DYRK1A	S479	S479G	479	Missense	central	0	yes	41.618	0.000	EPSD	COSMIC;GDSC;CCLE	34.163	Loss
CMGC_DYRK_DYRK1_DYRK1A_ST	O76039	CDKL5	Q13627	DYRK1A	S479	P474S	474	Missense	distal	-5	no	41.618	40.864	EPSD	COSMIC	34.163	Down-regulation
CMGC_DYRK_DYRK1_DYRK1A_ST	O76039	CDKL5	Q13627	DYRK1A	S526	P530L	530	Missense	distal	4	no	32.468	34.515	EPSD	COSMIC	34.163	Gain
CMGC_DYRK_DYRK1_DYRK1A_ST	O76039	CDKL5	Q13627	DYRK1A	S529	S526Y	526	Missense	distal	-3	no	51.791	42.394	EPSD	COSMIC	34.163	Down-regulation
CMGC_DYRK_DYRK1_DYRK1A_ST	O76039	CDKL5	Q13627	DYRK1A	S529	P530L	530	Missense	proximal	1	no	51.791	9.460	EPSD	COSMIC	34.163	Loss
CMGC_DYRK_DYRK1_DYRK1A_ST	O76039	CDKL5	Q13627	DYRK1A	S529	T528P	528	Missense	proximal	-1	no	51.791	52.441	EPSD	COSMIC	34.163	Up-regulation
CMGC_DYRK_DYRK1_DYRK1A_ST	O76039	CDKL5	Q13627	DYRK1A	S529	P532L	532	Missense	distal	3	no	51.791	51.798	EPSD	COSMIC	34.163	Up-regulation
CMGC_DYRK_DYRK1_DYRK1A_ST	O76039	CDKL5	Q13627	DYRK1A	T531	S526Y	526	Missense	distal	-5	no	36.608	36.260	EPSD	COSMIC	34.163	Down-regulation
CMGC_DYRK_DYRK1_DYRK1A_ST	O76039	CDKL5	Q13627	DYRK1A	T531	P530L	530	Missense	proximal	-1	no	36.608	36.832	EPSD	COSMIC	34.163	Up-regulation
CMGC_DYRK_DYRK1_DYRK1A_ST	O76039	CDKL5	Q13627	DYRK1A	T531	T528P	528	Missense	distal	-3	no	36.608	42.855	EPSD	COSMIC	34.163	Up-regulation
CMGC_DYRK_DYRK1_DYRK1A_ST	O76039	CDKL5	Q13627	DYRK1A	T531	P532L	532	Missense	proximal	1	no	36.608	-5.723	EPSD	COSMIC	34.163	Loss
CMGC_DYRK_DYRK1_DYRK1A_ST	O76039	CDKL5	Q13627	DYRK1A	S681	G684A	684	Missense	distal	3	no	38.784	38.854	EPSD	COSMIC	34.163	Up-regulation
CMGC_DYRK_DYRK1_DYRK1A_ST	O76039	CDKL5	Q13627	DYRK1A	S681	D688N	688	Missense	distal	7	no	38.784	39.873	EPSD	COSMIC	34.163	Up-regulation
CMGC_DYRK_DYRK1_DYRK1A_ST	O76039	CDKL5	Q13627	DYRK1A	S714	P721L	721	Missense	distal	7	no	36.380	38.039	EPSD	COSMIC	34.163	Up-regulation
CMGC_DYRK_DYRK1_DYRK1A_ST	O76039	CDKL5	Q13627	DYRK1A	S720	R722H	722	Missense	proximal	2	no	52.932	51.810	EPSD	COSMIC	34.163	Down-regulation
CMGC_DYRK_DYRK1_DYRK1A_ST	O76039	CDKL5	Q13627	DYRK1A	S720	P721L	721	Missense	proximal	1	no	52.932	10.601	EPSD	COSMIC	34.163	Loss
CMGC_DYRK_DYRK1_DYRK1A_ST	O76039	CDKL5	Q13627	DYRK1A	S761	E763G	763	Missense	proximal	2	no	34.273	34.533	EPSD	COSMIC	34.163	Up-regulation
CMGC_DYRK_DYRK1_DYRK1A_ST	O76039	CDKL5	Q13627	DYRK1A	S761	S766G	766	Missense	distal	5	no	34.273	35.499	EPSD	COSMIC	34.163	Up-regulation
CMGC_DYRK_DYRK1_DYRK1A_ST	O76039	CDKL5	Q13627	DYRK1A	S761	D757N	757	Missense	distal	-4	no	34.273	34.277	EPSD	COSMIC	34.163	Up-regulation
CMGC_DYRK_DYRK1_DYRK1A_ST	O76039	CDKL5	Q13627	DYRK1A	T813	E820K	820	Missense	distal	7	no	36.353	37.984	EPSD	COSMIC	34.163	Up-regulation
CMGC_DYRK_DYRK1_DYRK1A_ST	O76039	CDKL5	Q13627	DYRK1A	T813	S816G	816	Missense	distal	3	no	36.353	36.092	EPSD	COSMIC	34.163	Down-regulation
CMGC_DYRK_DYRK1_DYRK1A_ST	P37840	SNCA	Q13627	DYRK1A	T81	V82G	82	Missense	proximal	1	no	38.024	33.195	EPSD	COSMIC	34.163	Loss
CMGC_DYRK_DYRK1_DYRK1A_ST	P37840	SNCA	Q13627	DYRK1A	S87	V82G	82	Missense	distal	-5	no	53.617	53.891	PhosphoSitePlus	COSMIC	34.163	Up-regulation
CMGC_DYRK_DYRK1_DYRK1A_ST	Q05193	DNM1	Q13627	DYRK1A	S126	L132M	132	Missense	distal	6	no	38.404	38.494	EPSD	COSMIC;GDSC;CCLE	34.163	Up-regulation
CMGC_DYRK_DYRK1_DYRK1A_ST	Q05193	DNM1	Q13627	DYRK1A	S126	R123G	123	Missense	distal	-3	no	38.404	29.209	EPSD	COSMIC	34.163	Loss
CMGC_DYRK_DYRK1_DYRK1A_ST	Q05193	DNM1	Q13627	DYRK1A	S126	P119H	119	Missense	distal	-7	no	38.404	38.514	EPSD	COSMIC;GDSC;CCLE	34.163	Up-regulation
CMGC_DYRK_DYRK1_DYRK1A_ST	Q05193	DNM1	Q13627	DYRK1A	T274	R271C	271	Missense	distal	-3	no	47.343	23.839	EPSD	COSMIC	34.163	Loss
CMGC_DYRK_DYRK1_DYRK1A_ST	Q05193	DNM1	Q13627	DYRK1A	S851	R846G	846	Missense	distal	-5	no	40.410	39.556	EPSD	COSMIC	34.163	Down-regulation
CMGC_DYRK_DYRK1_DYRK1A_ST	Q05193	DNM1	Q13627	DYRK1A	S851	P855Q	855	Missense	distal	4	no	40.410	41.712	EPSD	COSMIC	34.163	Up-regulation
CMGC_DYRK_DYRK1_DYRK1A_ST	Q05193	DNM1	Q13627	DYRK1A	S857	R859S	859	Missense	proximal	2	no	64.607	64.106	PhosphoSitePlus	COSMIC	34.163	Down-regulation
CMGC_DYRK_DYRK1_DYRK1A_ST	Q05193	DNM1	Q13627	DYRK1A	S857	P855Q	855	Missense	proximal	-2	no	64.607	59.217	PhosphoSitePlus	COSMIC	34.163	Down-regulation
CMGC_DYRK_HIPK_HIPK1_ST	O60829	PAGE4	Q86Z02	HIPK1	T51	G45E	45	Missense	distal	-6	no	8.683	8.707	PhosphoSitePlus	COSMIC	1.785	Up-regulation
CMGC_DYRK_HIPK_HIPK1_ST	O60829	PAGE4	Q86Z02	HIPK1	T51	P53A	53	Missense	proximal	2	no	8.683	8.180	PhosphoSitePlus	COSMIC;GDSC;CCLE	1.785	Down-regulation
CMGC_DYRK_HIPK_HIPK1_ST	P51608	MECP2	Q86Z02	HIPK1	S65	A71T	71	Missense	distal	6	no	1.765	1.824	EPSD	COSMIC;CCLE	1.785	Gain
CMGC_DYRK_HIPK_HIPK1_ST	P51608	MECP2	Q86Z02	HIPK1	S178	P172S	172	Missense	distal	-6	no	4.226	4.122	EPSD	COSMIC	1.785	Down-regulation
CMGC_DYRK_HIPK_HIPK1_ST	P51608	MECP2	Q86Z02	HIPK1	S178	T184P	184	Missense	distal	6	no	4.226	4.274	EPSD	COSMIC	1.785	Up-regulation
CMGC_DYRK_HIPK_HIPK1_ST	P51608	MECP2	Q86Z02	HIPK1	S178	P172A	172	Missense	distal	-6	no	4.226	4.135	EPSD	COSMIC	1.785	Down-regulation
CMGC_DYRK_HIPK_HIPK1_ST	P51608	MECP2	Q86Z02	HIPK1	S216	P217L	217	Missense	proximal	1	no	7.998	4.624	PhosphoSitePlus;EPSD	COSMIC	1.785	Down-regulation
CMGC_DYRK_HIPK_HIPK1_ST	P51608	MECP2	Q86Z02	HIPK1	S216	V212G	212	Missense	distal	-4	no	7.998	7.869	PhosphoSitePlus;EPSD	COSMIC	1.785	Down-regulation
CMGC_DYRK_HIPK_HIPK1_ST	P51608	MECP2	Q86Z02	HIPK1	S229	P230S	230	Missense	proximal	1	no	3.042	-0.275	EPSD	COSMIC;CCLE	1.785	Loss
CMGC_DYRK_HIPK_HIPK1_ST	P51608	MECP2	Q86Z02	HIPK1	S229	S229A	229	Missense	central	0	yes	3.042	0.000	EPSD	COSMIC	1.785	Loss
CMGC_DYRK_HIPK_HIPK1_ST	P51608	MECP2	Q86Z02	HIPK1	S229	P225L	225	Missense	distal	-4	no	3.042	2.986	EPSD	COSMIC	1.785	Down-regulation
CMGC_DYRK_HIPK_HIPK1_ST	P51608	MECP2	Q86Z02	HIPK1	S350	K352Q	352	Missense	proximal	2	no	2.272	2.191	EPSD	COSMIC	1.785	Down-regulation
CMGC_DYRK_HIPK_HIPK1_ST	P51608	MECP2	Q86Z02	HIPK1	S350	K352N	352	Missense	proximal	2	no	2.272	2.273	EPSD	COSMIC	1.785	Up-regulation
CMGC_DYRK_HIPK_HIPK1_ST	P51608	MECP2	Q86Z02	HIPK1	S350	R344Q	344	Missense	distal	-6	no	2.272	2.171	EPSD	COSMIC	1.785	Down-regulation
CMGC_DYRK_HIPK_HIPK1_ST	P51608	MECP2	Q86Z02	HIPK1	S350	S349R	349	Missense	proximal	-1	no	2.272	2.318	EPSD	COSMIC	1.785	Up-regulation
CMGC_DYRK_HIPK_HIPK1_ST	P51608	MECP2	Q86Z02	HIPK1	S359	K352Q	352	Missense	distal	-7	no	1.812	1.817	EPSD	COSMIC	1.785	Up-regulation
CMGC_DYRK_HIPK_HIPK1_ST	P51608	MECP2	Q86Z02	HIPK1	S359	K352N	352	Missense	distal	-7	no	1.812	1.828	EPSD	COSMIC	1.785	Up-regulation
CMGC_DYRK_HIPK_HIPK1_ST	P51608	MECP2	Q86Z02	HIPK1	S396	P403H	403	Missense	distal	7	no	3.015	3.020	EPSD	COSMIC	1.785	Up-regulation
CMGC_DYRK_HIPK_HIPK1_ST	P51608	MECP2	Q86Z02	HIPK1	S396	P391S	391	Missense	distal	-5	no	3.015	3.265	EPSD	COSMIC;GDSC	1.785	Up-regulation
CMGC_DYRK_HIPK_HIPK1_ST	P51608	MECP2	Q86Z02	HIPK1	S401	P403H	403	Missense	proximal	2	no	3.090	2.616	EPSD	COSMIC	1.785	Down-regulation
CMGC_DYRK_HIPK_HIPK1_ST	P51608	MECP2	Q86Z02	HIPK1	T436	Q437E	437	Missense	proximal	1	no	1.576	1.986	EPSD	COSMIC	1.785	Gain
CMGC_DYRK_HIPK_HIPK1_ST	P51608	MECP2	Q86Z02	HIPK1	T479	P480L	480	Missense	proximal	1	no	3.273	-0.101	EPSD	COSMIC	1.785	Loss
CMGC_DYRK_HIPK_HIPK1_ST	P51608	MECP2	Q86Z02	HIPK1	T479	V481M	481	Missense	proximal	2	no	3.273	3.279	EPSD	COSMIC	1.785	Up-regulation
Other_NEK_NEK11_NEK11_ST	P30304	CDC25A	Q8NG66	NEK11	S76	N70H	70	Missense	distal	-6	no	3.375	3.280	EPSD	COSMIC	2.788	Down-regulation
Other_NEK_NEK11_NEK11_ST	P30304	CDC25A	Q8NG66	NEK11	S76	S69G	69	Missense	distal	-7	no	3.375	3.373	EPSD	COSMIC	2.788	Down-regulation
Other_NEK_NEK11_NEK11_ST	P30304	CDC25A	Q8NG66	NEK11	S263	L264V	264	Missense	proximal	1	no	3.708	3.726	EPSD	COSMIC	2.788	Up-regulation
Other_NEK_NEK11_NEK11_ST	P30304	CDC25A	Q8NG66	NEK11	S263	R270Q	270	Missense	distal	7	no	3.708	3.694	EPSD	COSMIC	2.788	Down-regulation
Other_NEK_NEK11_NEK11_ST	P30304	CDC25A	Q8NG66	NEK11	S293	S293N	293	Missense	central	0	yes	3.687	0.000	EPSD	COSMIC	2.788	Loss
Other_NEK_NEK11_NEK11_ST	P30304	CDC25A	Q8NG66	NEK11	S320	P322L	322	Missense	proximal	2	no	3.121	3.034	EPSD	COSMIC	2.788	Down-regulation
Other_NEK_NEK11_NEK11_ST	P30304	CDC25A	Q8NG66	NEK11	S320	S320Y	320	Missense	central	0	yes	3.121	0.000	EPSD	COSMIC	2.788	Loss
Other_NEK_NEK11_NEK11_ST	P30304	CDC25A	Q8NG66	NEK11	S342	T349I	349	Missense	distal	7	no	4.210	4.247	EPSD	COSMIC;GDSC;CCLE	2.788	Up-regulation
Other_NEK_NEK11_NEK11_ST	P54132	BLM	Q8NG66	NEK11	S17	E11Q	11	Missense	distal	-6	no	3.432	3.419	EPSD	COSMIC	2.788	Down-regulation
Other_NEK_NEK11_NEK11_ST	P54132	BLM	Q8NG66	NEK11	S28	K31N	31	Missense	distal	3	no	3.082	3.180	EPSD	COSMIC	2.788	Up-regulation
Other_NEK_NEK11_NEK11_ST	P54132	BLM	Q8NG66	NEK11	S28	K29E	29	Missense	proximal	1	no	3.082	3.028	EPSD	COSMIC	2.788	Down-regulation
Other_NEK_NEK11_NEK11_ST	P54132	BLM	Q8NG66	NEK11	S28	F35Y	35	Missense	distal	7	no	3.082	3.058	EPSD	COSMIC	2.788	Down-regulation
Other_NEK_NEK11_NEK11_ST	P54132	BLM	Q8NG66	NEK11	S28	L27F	27	Missense	proximal	-1	no	3.082	3.625	EPSD	COSMIC	2.788	Up-regulation
Other_NEK_NEK11_NEK11_ST	P54132	BLM	Q8NG66	NEK11	S28	F32I	32	Missense	distal	4	no	3.082	3.029	EPSD	COSMIC	2.788	Down-regulation
Other_NEK_NEK11_NEK11_ST	P54132	BLM	Q8NG66	NEK11	S48	T41A	41	Missense	distal	-7	no	3.483	3.464	EPSD	COSMIC	2.788	Down-regulation
Other_NEK_NEK11_NEK11_ST	P54132	BLM	Q8NG66	NEK11	S48	V54I	54	Missense	distal	6	no	3.483	3.501	EPSD	COSMIC	2.788	Up-regulation
Other_NEK_NEK11_NEK11_ST	P54132	BLM	Q8NG66	NEK11	S48	N45S	45	Missense	distal	-3	no	3.483	3.520	EPSD	COSMIC	2.788	Up-regulation
Other_NEK_NEK11_NEK11_ST	P54132	BLM	Q8NG66	NEK11	S48	S42Y	42	Missense	distal	-6	no	3.483	3.307	EPSD	COSMIC	2.788	Down-regulation
Other_NEK_NEK11_NEK11_ST	P54132	BLM	Q8NG66	NEK11	S142	L136V	136	Missense	distal	-6	no	2.697	2.837	EPSD	COSMIC	2.788	Gain
Other_NEK_NEK11_NEK11_ST	P54132	BLM	Q8NG66	NEK11	S144	S147F	147	Missense	distal	3	no	3.260	3.169	EPSD	COSMIC	2.788	Down-regulation
Other_NEK_NEK11_NEK11_ST	P54132	BLM	Q8NG66	NEK11	S144	S144L	144	Missense	central	0	yes	3.260	0.000	EPSD	COSMIC	2.788	Loss
Other_NEK_NEK11_NEK11_ST	P54132	BLM	Q8NG66	NEK11	S144	T150I	150	Missense	distal	6	no	3.260	3.313	EPSD	COSMIC	2.788	Up-regulation
Other_NEK_NEK11_NEK11_ST	P54132	BLM	Q8NG66	NEK11	S144	I151M	151	Missense	distal	7	no	3.260	3.297	EPSD	COSMIC	2.788	Up-regulation
Other_NEK_NEK11_NEK11_ST	P54132	BLM	Q8NG66	NEK11	S147	I151M	151	Missense	distal	4	no	2.671	3.021	EPSD	COSMIC	2.788	Gain
Other_NEK_NEK11_NEK11_ST	P54132	BLM	Q8NG66	NEK11	S168	E164K	164	Missense	distal	-4	no	3.481	3.120	EPSD	COSMIC	2.788	Down-regulation
Other_NEK_NEK11_NEK11_ST	P54132	BLM	Q8NG66	NEK11	S168	S168L	168	Missense	central	0	yes	3.481	0.000	EPSD	COSMIC	2.788	Loss
Other_NEK_NEK11_NEK11_ST	P54132	BLM	Q8NG66	NEK11	S168	S163Y	163	Missense	distal	-5	no	3.481	3.516	EPSD	COSMIC	2.788	Up-regulation
Other_NEK_NEK11_NEK11_ST	P54132	BLM	Q8NG66	NEK11	S315	S315Y	315	Missense	central	0	yes	3.222	0.000	EPSD	COSMIC	2.788	Loss
Other_NEK_NEK11_NEK11_ST	P54132	BLM	Q8NG66	NEK11	S315	C318S	318	Missense	distal	3	no	3.222	3.187	EPSD	COSMIC;GDSC;CCLE	2.788	Down-regulation
Other_NEK_NEK11_NEK11_ST	P54132	BLM	Q8NG66	NEK11	S338	D340N	340	Missense	proximal	2	no	8.770	8.731	PhosphoSitePlus	COSMIC	2.788	Down-regulation
Other_NEK_NEK11_NEK11_ST	P54132	BLM	Q8NG66	NEK11	S338	L341I	341	Missense	distal	3	no	8.770	8.827	PhosphoSitePlus	COSMIC	2.788	Up-regulation
Other_NEK_NEK11_NEK11_ST	P54132	BLM	Q8NG66	NEK11	S338	S343L	343	Missense	distal	5	no	8.770	8.600	PhosphoSitePlus	COSMIC	2.788	Down-regulation
Other_NEK_NEK11_NEK11_ST	P54132	BLM	Q8NG66	NEK11	S349	E356K	356	Missense	distal	7	no	3.252	3.256	EPSD	COSMIC	2.788	Up-regulation
Other_NEK_NEK11_NEK11_ST	P54132	BLM	Q8NG66	NEK11	S349	P355L	355	Missense	distal	6	no	3.252	3.253	EPSD	COSMIC	2.788	Up-regulation
Other_NEK_NEK11_NEK11_ST	P54132	BLM	Q8NG66	NEK11	S349	K347N	347	Missense	proximal	-2	no	3.252	3.303	EPSD	COSMIC;GDSC;CCLE	2.788	Up-regulation
Other_NEK_NEK11_NEK11_ST	P54132	BLM	Q8NG66	NEK11	S349	S343L	343	Missense	distal	-6	no	3.252	2.909	EPSD	COSMIC	2.788	Down-regulation
Other_NEK_NEK11_NEK11_ST	P54132	BLM	Q8NG66	NEK11	S358	E356K	356	Missense	proximal	-2	no	3.870	3.765	EPSD	COSMIC	2.788	Down-regulation
Other_NEK_NEK11_NEK11_ST	P54132	BLM	Q8NG66	NEK11	S358	C361Y	361	Missense	distal	3	no	3.870	3.860	EPSD	COSMIC;CCLE	2.788	Down-regulation
Other_NEK_NEK11_NEK11_ST	P54132	BLM	Q8NG66	NEK11	S358	P355L	355	Missense	distal	-3	no	3.870	3.940	EPSD	COSMIC	2.788	Up-regulation
Other_NEK_NEK11_NEK11_ST	P54132	BLM	Q8NG66	NEK11	S358	A363S	363	Missense	distal	5	no	3.870	3.950	EPSD	COSMIC	2.788	Up-regulation
Other_NEK_NEK11_NEK11_ST	P54132	BLM	Q8NG66	NEK11	S443	T446I	446	Missense	distal	3	no	4.037	3.902	EPSD	COSMIC	2.788	Down-regulation
Other_NEK_NEK11_NEK11_ST	P54132	BLM	Q8NG66	NEK11	T528	Q533H	533	Missense	distal	5	no	3.192	3.121	EPSD	COSMIC	2.788	Down-regulation
Other_NEK_NEK11_NEK11_ST	P54132	BLM	Q8NG66	NEK11	S539	Q533H	533	Missense	distal	-6	no	3.884	3.764	EPSD	COSMIC	2.788	Down-regulation
Other_NEK_NEK11_NEK11_ST	P54132	BLM	Q8NG66	NEK11	S580	S580P	580	Missense	central	0	yes	3.086	0.000	EPSD	COSMIC	2.788	Loss
Other_NEK_NEK11_NEK11_ST	P54132	BLM	Q8NG66	NEK11	S601	D606N	606	Missense	distal	5	no	2.848	2.883	EPSD	COSMIC	2.788	Up-regulation
Other_NEK_NEK11_NEK11_ST	P54132	BLM	Q8NG66	NEK11	S601	R599K	599	Missense	proximal	-2	no	2.848	2.872	EPSD	COSMIC	2.788	Up-regulation
Other_NEK_NEK11_NEK11_ST	P54132	BLM	Q8NG66	NEK11	S646	S646G	646	Missense	central	0	yes	3.176	0.000	EPSD	COSMIC	2.788	Loss
Other_NEK_NEK11_NEK11_ST	P54132	BLM	Q8NG66	NEK11	S1138	G1134C	1134	Missense	distal	-4	no	3.400	3.081	EPSD	COSMIC	2.788	Down-regulation
Other_NEK_NEK11_NEK11_ST	P54132	BLM	Q8NG66	NEK11	S1138	N1141S	1141	Missense	distal	3	no	3.400	3.344	EPSD	COSMIC;GDSC;CCLE	2.788	Down-regulation
Other_NEK_NEK11_NEK11_ST	P54132	BLM	Q8NG66	NEK11	S1138	R1139Q	1139	Missense	proximal	1	no	3.400	3.433	EPSD	COSMIC;CCLE	2.788	Up-regulation
Other_NEK_NEK11_NEK11_ST	P54132	BLM	Q8NG66	NEK11	S1138	H1140Q	1140	Missense	proximal	2	no	3.400	3.436	EPSD	COSMIC	2.788	Up-regulation
Other_NEK_NEK11_NEK11_ST	P54132	BLM	Q8NG66	NEK11	S1280	Q1283H	1283	Missense	distal	3	no	2.855	2.996	EPSD	COSMIC	2.788	Up-regulation
Other_NEK_NEK11_NEK11_ST	P54132	BLM	Q8NG66	NEK11	S1290	Q1283H	1283	Missense	distal	-7	no	2.965	2.938	EPSD	COSMIC	2.788	Down-regulation
Other_NEK_NEK11_NEK11_ST	P54132	BLM	Q8NG66	NEK11	S1290	S1290L	1290	Missense	central	0	yes	2.965	0.000	EPSD	COSMIC	2.788	Loss
Other_NEK_NEK11_NEK11_ST	P54132	BLM	Q8NG66	NEK11	S1295	S1302F	1302	Missense	distal	7	no	3.026	3.117	EPSD	COSMIC	2.788	Up-regulation
Other_NEK_NEK11_NEK11_ST	P54132	BLM	Q8NG66	NEK11	S1295	S1290L	1290	Missense	distal	-5	no	3.026	3.091	EPSD	COSMIC	2.788	Up-regulation
Other_NEK_NEK11_NEK11_ST	P54132	BLM	Q8NG66	NEK11	S1310	L1315F	1315	Missense	distal	5	no	2.822	3.000	EPSD	COSMIC	2.788	Up-regulation
Other_NEK_NEK11_NEK11_ST	P54132	BLM	Q8NG66	NEK11	S1310	E1317D	1317	Missense	distal	7	no	2.822	2.837	EPSD	COSMIC	2.788	Up-regulation
Other_NEK_NEK11_NEK11_ST	P54132	BLM	Q8NG66	NEK11	S1310	E1317K	1317	Missense	distal	7	no	2.822	2.826	EPSD	COSMIC	2.788	Up-regulation
Other_NEK_NEK11_NEK11_ST	P54132	BLM	Q8NG66	NEK11	S1383	A1382T	1382	Missense	proximal	-1	no	2.682	3.208	EPSD	COSMIC	2.788	Gain
TK_Jak_JAK2_Y	P78347	GTF2I	O60674	JAK2	Y248	E242K	242	Missense	distal	-6	no	6.637	6.492	PhosphoSitePlus	COSMIC	5.995	Down-regulation
TK_Jak_JAK2_Y	P62993	GRB2	O60674	JAK2	Y7	F9L	9	Missense	proximal	2	no	6.767	7.894	EPSD;PhosphoSitePlus	COSMIC	5.995	Up-regulation
TK_Jak_JAK2_Y	P62993	GRB2	O60674	JAK2	Y52	G46S	46	Missense	distal	-6	no	9.250	9.671	EPSD;PhosphoSitePlus	COSMIC	5.995	Up-regulation
TK_Jak_JAK2_Y	Q13153	PAK1	O60674	JAK2	Y142	K141E	141	Missense	proximal	-1	no	5.826	6.989	EPSD	COSMIC	5.995	Gain
TK_Jak_JAK2_Y	Q13153	PAK1	O60674	JAK2	Y153	S155Y	155	Missense	proximal	2	no	10.814	8.831	EPSD;PhosphoSitePlus	COSMIC	5.995	Down-regulation
TK_Jak_JAK2_Y	Q13153	PAK1	O60674	JAK2	Y153	E151K	151	Missense	proximal	-2	no	10.814	9.486	EPSD;PhosphoSitePlus	COSMIC	5.995	Down-regulation
TK_Jak_JAK2_Y	Q13153	PAK1	O60674	JAK2	Y153	D152H	152	Missense	proximal	-1	no	10.814	9.719	EPSD;PhosphoSitePlus	COSMIC	5.995	Down-regulation
TK_Jak_JAK2_Y	Q13153	PAK1	O60674	JAK2	Y201	R203W	203	Missense	proximal	2	no	8.459	6.048	EPSD;PhosphoSitePlus	COSMIC	5.995	Down-regulation
TK_Jak_JAK2_Y	Q13153	PAK1	O60674	JAK2	Y201	K198Q	198	Missense	distal	-3	no	8.459	8.520	EPSD;PhosphoSitePlus	COSMIC	5.995	Up-regulation
TK_Jak_JAK2_Y	Q13153	PAK1	O60674	JAK2	Y201	P208L	208	Missense	distal	7	no	8.459	8.342	EPSD;PhosphoSitePlus	COSMIC	5.995	Down-regulation
TK_Jak_JAK2_Y	Q13153	PAK1	O60674	JAK2	Y201	Y201C	201	Missense	central	0	yes	8.459	0.000	EPSD;PhosphoSitePlus	COSMIC	5.995	Loss
TK_Jak_JAK2_Y	Q13153	PAK1	O60674	JAK2	Y285	G282V	282	Missense	distal	-3	no	9.010	10.939	PhosphoSitePlus;EPSD	COSMIC	5.995	Up-regulation
TK_Jak_JAK2_Y	O14744	PRMT5	O60674	JAK2	Y297	P294L	294	Missense	distal	-3	no	9.120	7.723	EPSD;PhosphoSitePlus	COSMIC	5.995	Down-regulation
TK_Jak_JAK2_Y	O14744	PRMT5	O60674	JAK2	Y297	P292L	292	Missense	distal	-5	no	9.120	9.216	EPSD;PhosphoSitePlus	COSMIC	5.995	Up-regulation
TK_Jak_JAK2_Y	O14744	PRMT5	O60674	JAK2	Y304	P311L	311	Missense	distal	7	no	8.666	8.549	EPSD;PhosphoSitePlus	COSMIC	5.995	Down-regulation
TK_Jak_JAK2_Y	O14744	PRMT5	O60674	JAK2	Y307	P311L	311	Missense	distal	4	no	9.079	9.013	PhosphoSitePlus;EPSD	COSMIC	5.995	Down-regulation
TK_Jak_JAK2_Y	Q9UGK3	STAP2	O60674	JAK2	Y250	P243S	243	Missense	distal	-7	no	11.373	11.148	PhosphoSitePlus;EPSD	COSMIC	5.995	Down-regulation
TK_Jak_JAK2_Y	O60674	JAK2	O60674	JAK2	Y119	Y124C	124	Missense	distal	5	no	13.126	11.822	EPSD;PhosphoSitePlus	COSMIC	5.995	Down-regulation
TK_Jak_JAK2_Y	O60674	JAK2	O60674	JAK2	Y119	V112A	112	Missense	distal	-7	no	13.126	12.769	EPSD;PhosphoSitePlus	COSMIC	5.995	Down-regulation
TK_Jak_JAK2_Y	O60674	JAK2	O60674	JAK2	Y119	P121A	121	Missense	proximal	2	no	13.126	14.555	EPSD;PhosphoSitePlus	COSMIC	5.995	Up-regulation
TK_Jak_JAK2_Y	O60674	JAK2	O60674	JAK2	Y201	S203F	203	Missense	proximal	2	no	6.956	4.784	EPSD	COSMIC	5.995	Loss
TK_Jak_JAK2_Y	O60674	JAK2	O60674	JAK2	Y201	D194N	194	Missense	distal	-7	no	6.956	7.995	EPSD	COSMIC;GDSC;CCLE	5.995	Up-regulation
TK_Jak_JAK2_Y	O60674	JAK2	O60674	JAK2	Y201	K207N	207	Missense	distal	6	no	6.956	6.139	EPSD	COSMIC;CCLE	5.995	Down-regulation
TK_Jak_JAK2_Y	O60674	JAK2	O60674	JAK2	Y201	S205R	205	Missense	distal	4	no	6.956	6.600	EPSD	COSMIC	5.995	Down-regulation
TK_Jak_JAK2_Y	O60674	JAK2	O60674	JAK2	Y201	K207R	207	Missense	distal	6	no	6.956	6.461	EPSD	COSMIC	5.995	Down-regulation
TK_Jak_JAK2_Y	O60674	JAK2	O60674	JAK2	Y221	L224W	224	Missense	distal	3	no	11.172	7.044	EPSD	COSMIC	5.995	Down-regulation
TK_Jak_JAK2_Y	O60674	JAK2	O60674	JAK2	Y221	R215L	215	Missense	distal	-6	no	11.172	10.741	EPSD	COSMIC	5.995	Down-regulation
TK_Jak_JAK2_Y	O60674	JAK2	O60674	JAK2	Y382	V387L	387	Missense	distal	5	no	6.018	4.726	EPSD	COSMIC	5.995	Loss
TK_Jak_JAK2_Y	O60674	JAK2	O60674	JAK2	Y382	H381Y	381	Missense	proximal	-1	no	6.018	5.729	EPSD	COSMIC	5.995	Loss
TK_Jak_JAK2_Y	O60674	JAK2	O60674	JAK2	Y382	L383P	383	Missense	proximal	1	no	6.018	6.093	EPSD	COSMIC;GDSC;CCLE	5.995	Up-regulation
TK_Jak_JAK2_Y	O60674	JAK2	O60674	JAK2	Y570	V567A	567	Missense	distal	-3	no	9.653	10.691	EPSD;PhosphoSitePlus	COSMIC	5.995	Up-regulation
TK_Jak_JAK2_Y	O60674	JAK2	O60674	JAK2	Y570	R564L	564	Missense	distal	-6	no	9.653	9.222	EPSD;PhosphoSitePlus	COSMIC	5.995	Down-regulation
TK_Jak_JAK2_Y	O60674	JAK2	O60674	JAK2	Y570	V567L	567	Missense	distal	-3	no	9.653	8.523	EPSD;PhosphoSitePlus	COSMIC	5.995	Down-regulation
TK_Jak_JAK2_Y	O60674	JAK2	O60674	JAK2	Y570	G571R	571	Missense	proximal	1	no	9.653	9.912	EPSD;PhosphoSitePlus	COSMIC	5.995	Up-regulation
TK_Jak_JAK2_Y	O60674	JAK2	O60674	JAK2	Y570	V567E	567	Missense	distal	-3	no	9.653	8.433	EPSD;PhosphoSitePlus	COSMIC	5.995	Down-regulation
TK_Jak_JAK2_Y	O60674	JAK2	O60674	JAK2	Y570	R564G	564	Missense	distal	-6	no	9.653	9.281	EPSD;PhosphoSitePlus	COSMIC	5.995	Down-regulation
TK_Jak_JAK2_Y	O60674	JAK2	O60674	JAK2	Y637	K630N	630	Missense	distal	-7	no	7.231	8.087	EPSD	COSMIC	5.995	Up-regulation
TK_Jak_JAK2_Y	O60674	JAK2	O60674	JAK2	Y637	N643S	643	Missense	distal	6	no	7.231	7.644	EPSD	COSMIC	5.995	Up-regulation
TK_Jak_JAK2_Y	O60674	JAK2	O60674	JAK2	Y790	I784R	784	Missense	distal	-6	no	5.531	6.385	EPSD	COSMIC	5.995	Gain
TK_Jak_JAK2_Y	O60674	JAK2	O60674	JAK2	Y813	D820V	820	Missense	distal	7	no	7.455	7.212	EPSD	COSMIC	5.995	Down-regulation
TK_Jak_JAK2_Y	O60674	JAK2	O60674	JAK2	Y813	L808W	808	Missense	distal	-5	no	7.455	7.528	EPSD	COSMIC	5.995	Up-regulation
TK_Jak_JAK2_Y	O60674	JAK2	O60674	JAK2	Y813	E818K	818	Missense	distal	5	no	7.455	7.612	EPSD	COSMIC	5.995	Up-regulation
TK_Jak_JAK2_Y	O60674	JAK2	O60674	JAK2	Y813	Y813D	813	Missense	central	0	yes	7.455	0.000	EPSD	COSMIC	5.995	Loss
TK_Jak_JAK2_Y	O60674	JAK2	O60674	JAK2	Y868	R867Q	867	Missense	proximal	-1	no	8.754	8.396	EPSD	COSMIC	5.995	Down-regulation
TK_Jak_JAK2_Y	O60674	JAK2	O60674	JAK2	Y868	G861W	861	Missense	distal	-7	no	8.754	8.858	EPSD	COSMIC	5.995	Up-regulation
TK_Jak_JAK2_Y	O60674	JAK2	O60674	JAK2	Y868	T875N	875	Missense	distal	7	no	8.754	8.758	EPSD	COSMIC	5.995	Up-regulation
TK_Jak_JAK2_Y	O60674	JAK2	O60674	JAK2	Y868	L871V	871	Missense	distal	3	no	8.754	7.577	EPSD	COSMIC;CCLE	5.995	Down-regulation
TK_Jak_JAK2_Y	O60674	JAK2	O60674	JAK2	Y868	C866F	866	Missense	proximal	-2	no	8.754	7.699	EPSD	COSMIC	5.995	Down-regulation
TK_Jak_JAK2_Y	O60674	JAK2	O60674	JAK2	Y868	R867P	867	Missense	proximal	-1	no	8.754	8.274	EPSD	COSMIC	5.995	Down-regulation
TK_Jak_JAK2_Y	O60674	JAK2	O60674	JAK2	Y868	R867W	867	Missense	proximal	-1	no	8.754	7.915	EPSD	COSMIC	5.995	Down-regulation
TK_Jak_JAK2_Y	O60674	JAK2	O60674	JAK2	Y931	Y931C	931	Missense	central	0	yes	7.047	0.000	EPSD	COSMIC	5.995	Loss
TK_Jak_JAK2_Y	O60674	JAK2	O60674	JAK2	Y931	P933R	933	Missense	proximal	2	no	7.047	6.617	EPSD	COSMIC	5.995	Down-regulation
TK_Jak_JAK2_Y	O60674	JAK2	O60674	JAK2	Y931	N924K	924	Missense	distal	-7	no	7.047	6.191	EPSD	COSMIC	5.995	Down-regulation
TK_Jak_JAK2_Y	O60674	JAK2	O60674	JAK2	Y931	R938Q	938	Missense	distal	7	no	7.047	6.747	EPSD	COSMIC	5.995	Down-regulation
TK_Jak_JAK2_Y	O60674	JAK2	O60674	JAK2	Y931	L925P	925	Missense	distal	-6	no	7.047	7.752	EPSD	COSMIC	5.995	Up-regulation
TK_Jak_JAK2_Y	O60674	JAK2	O60674	JAK2	Y931	P933Q	933	Missense	proximal	2	no	7.047	6.061	EPSD	COSMIC	5.995	Down-regulation
TK_Jak_JAK2_Y	O60674	JAK2	O60674	JAK2	Y931	M929L	929	Missense	proximal	-2	no	7.047	3.688	EPSD	COSMIC	5.995	Loss
TK_Jak_JAK2_Y	O60674	JAK2	O60674	JAK2	Y934	Y931C	931	Missense	distal	-3	no	7.812	7.284	EPSD	COSMIC	5.995	Down-regulation
TK_Jak_JAK2_Y	O60674	JAK2	O60674	JAK2	Y934	P933R	933	Missense	proximal	-1	no	7.812	8.293	EPSD	COSMIC	5.995	Up-regulation
TK_Jak_JAK2_Y	O60674	JAK2	O60674	JAK2	Y934	R938Q	938	Missense	distal	4	no	7.812	7.899	EPSD	COSMIC	5.995	Up-regulation
TK_Jak_JAK2_Y	O60674	JAK2	O60674	JAK2	Y934	P933Q	933	Missense	proximal	-1	no	7.812	7.935	EPSD	COSMIC	5.995	Up-regulation
TK_Jak_JAK2_Y	O60674	JAK2	O60674	JAK2	Y934	M929L	929	Missense	distal	-5	no	7.812	7.874	EPSD	COSMIC	5.995	Up-regulation
TK_Jak_JAK2_Y	O60674	JAK2	O60674	JAK2	Y940	E946Q	946	Missense	distal	6	no	7.513	7.968	EPSD	COSMIC	5.995	Up-regulation
TK_Jak_JAK2_Y	O60674	JAK2	O60674	JAK2	Y940	P933R	933	Missense	distal	-7	no	7.513	7.835	EPSD	COSMIC	5.995	Up-regulation
TK_Jak_JAK2_Y	O60674	JAK2	O60674	JAK2	Y940	R947Q	947	Missense	distal	7	no	7.513	7.213	EPSD	COSMIC	5.995	Down-regulation
TK_Jak_JAK2_Y	O60674	JAK2	O60674	JAK2	Y940	R938Q	938	Missense	proximal	-2	no	7.513	7.655	EPSD	COSMIC	5.995	Up-regulation
TK_Jak_JAK2_Y	O60674	JAK2	O60674	JAK2	Y940	K945N	945	Missense	distal	5	no	7.513	7.391	EPSD	COSMIC	5.995	Down-regulation
TK_Jak_JAK2_Y	O60674	JAK2	O60674	JAK2	Y940	P933Q	933	Missense	distal	-7	no	7.513	7.138	EPSD	COSMIC	5.995	Down-regulation
TK_Jak_JAK2_Y	O60674	JAK2	O60674	JAK2	Y966	T969A	969	Missense	distal	3	no	8.263	6.532	EPSD	COSMIC	5.995	Down-regulation
TK_Jak_JAK2_Y	O60674	JAK2	O60674	JAK2	Y966	G968S	968	Missense	proximal	2	no	8.263	9.434	EPSD	COSMIC	5.995	Up-regulation
TK_Jak_JAK2_Y	O60674	JAK2	O60674	JAK2	Y966	G963S	963	Missense	distal	-3	no	8.263	11.262	EPSD	COSMIC	5.995	Up-regulation
TK_Jak_JAK2_Y	O60674	JAK2	O60674	JAK2	Y966	K962E	962	Missense	distal	-4	no	8.263	7.391	EPSD	COSMIC	5.995	Down-regulation
TK_Jak_JAK2_Y	O60674	JAK2	O60674	JAK2	Y966	E965D	965	Missense	proximal	-1	no	8.263	8.123	EPSD	COSMIC	5.995	Down-regulation
TK_Jak_JAK2_Y	O60674	JAK2	O60674	JAK2	Y972	D976N	976	Missense	distal	4	no	7.210	6.678	EPSD	COSMIC	5.995	Down-regulation
TK_Jak_JAK2_Y	O60674	JAK2	O60674	JAK2	Y972	T969A	969	Missense	distal	-3	no	7.210	9.762	EPSD	COSMIC	5.995	Up-regulation
TK_Jak_JAK2_Y	O60674	JAK2	O60674	JAK2	Y972	G968S	968	Missense	distal	-4	no	7.210	7.177	EPSD	COSMIC	5.995	Down-regulation
TK_Jak_JAK2_Y	O60674	JAK2	O60674	JAK2	Y972	E965D	965	Missense	distal	-7	no	7.210	6.821	EPSD	COSMIC	5.995	Down-regulation
TK_Jak_JAK2_Y	O60674	JAK2	O60674	JAK2	Y972	D976G	976	Missense	distal	4	no	7.210	6.956	EPSD	COSMIC	5.995	Down-regulation
TK_Jak_JAK2_Y	O60674	JAK2	O60674	JAK2	Y1007	E1006Q	1006	Missense	proximal	-1	no	9.986	9.051	EPSD	COSMIC	5.995	Down-regulation
TK_Jak_JAK2_Y	O60674	JAK2	O60674	JAK2	Y1008	E1006Q	1006	Missense	proximal	-2	no	8.850	8.258	EPSD	COSMIC	5.995	Down-regulation
TK_Jak_JAK2_Y	Q15910	EZH2	O60674	JAK2	Y23	R16Q	16	Missense	distal	-7	no	6.182	5.486	EPSD	COSMIC;GDSC;CCLE	5.995	Loss
TK_Jak_JAK2_Y	Q15910	EZH2	O60674	JAK2	Y23	Q28R	28	Missense	distal	5	no	6.182	7.890	EPSD	COSMIC	5.995	Up-regulation
TK_Jak_JAK2_Y	Q15910	EZH2	O60674	JAK2	Y23	L26P	26	Missense	distal	3	no	6.182	4.588	EPSD	COSMIC	5.995	Loss
TK_Jak_JAK2_Y	Q15910	EZH2	O60674	JAK2	Y23	R18H	18	Missense	distal	-5	no	6.182	6.272	EPSD	COSMIC	5.995	Up-regulation
TK_Jak_JAK2_Y	Q15910	EZH2	O60674	JAK2	Y23	R16W	16	Missense	distal	-7	no	6.182	6.479	EPSD	COSMIC	5.995	Up-regulation
TK_Jak_JAK2_Y	Q15910	EZH2	O60674	JAK2	Y244	L240P	240	Missense	distal	-4	no	5.637	6.092	EPSD	COSMIC	5.995	Gain
TK_Jak_JAK2_Y	Q15910	EZH2	O60674	JAK2	Y641	S639L	639	Missense	proximal	-2	no	9.471	6.836	PhosphoSitePlus	COSMIC	5.995	Down-regulation
TK_Jak_JAK2_Y	Q15910	EZH2	O60674	JAK2	Y641	S639P	639	Missense	proximal	-2	no	9.471	8.903	PhosphoSitePlus	COSMIC	5.995	Down-regulation
TK_Jak_JAK2_Y	Q15910	EZH2	O60674	JAK2	Y641	K634E	634	Missense	distal	-7	no	9.471	9.677	PhosphoSitePlus	COSMIC	5.995	Up-regulation
TK_Jak_JAK2_Y	Q15910	EZH2	O60674	JAK2	Y641	N635K	635	Missense	distal	-6	no	9.471	9.802	PhosphoSitePlus	COSMIC	5.995	Up-regulation
TK_Jak_JAK2_Y	Q15910	EZH2	O60674	JAK2	Y641	Q648E	648	Missense	distal	7	no	9.471	9.780	PhosphoSitePlus	COSMIC	5.995	Up-regulation
TK_Jak_JAK2_Y	Q15910	EZH2	O60674	JAK2	Y641	G643E	643	Missense	proximal	2	no	9.471	9.464	PhosphoSitePlus	COSMIC;CCLE	5.995	Down-regulation
TK_Jak_JAK2_Y	Q15910	EZH2	O60674	JAK2	Y641	S647F	647	Missense	distal	6	no	9.471	9.202	PhosphoSitePlus	COSMIC	5.995	Down-regulation
TK_Jak_JAK2_Y	Q15910	EZH2	O60674	JAK2	Y641	S647C	647	Missense	distal	6	no	9.471	9.175	PhosphoSitePlus	COSMIC	5.995	Down-regulation
TK_Jak_JAK2_Y	Q15910	EZH2	O60674	JAK2	Y641	G643V	643	Missense	proximal	2	no	9.471	9.347	PhosphoSitePlus	COSMIC	5.995	Down-regulation
TK_Jak_JAK2_Y	Q15910	EZH2	O60674	JAK2	Y641	E640K	640	Missense	proximal	-1	no	9.471	8.308	PhosphoSitePlus	COSMIC	5.995	Down-regulation
TK_Jak_JAK2_Y	Q15910	EZH2	O60674	JAK2	Y641	G643R	643	Missense	proximal	2	no	9.471	10.625	PhosphoSitePlus	COSMIC	5.995	Up-regulation
TK_Jak_JAK2_Y	Q15910	EZH2	O60674	JAK2	Y641	E636V	636	Missense	distal	-5	no	9.471	9.459	PhosphoSitePlus	COSMIC	5.995	Down-regulation
TK_Jak_JAK2_Y	Q15910	EZH2	O60674	JAK2	Y641	Y641D	641	Missense	central	0	yes	9.471	0.000	PhosphoSitePlus	COSMIC	5.995	Loss
TK_Jak_JAK2_Y	Q15910	EZH2	O60674	JAK2	Y641	Q648K	648	Missense	distal	7	no	9.471	9.669	PhosphoSitePlus	COSMIC	5.995	Up-regulation
TK_Jak_JAK2_Y	Q15910	EZH2	O60674	JAK2	Y641	I645S	645	Missense	distal	4	no	9.471	9.778	PhosphoSitePlus	COSMIC	5.995	Up-regulation
TK_Jak_JAK2_Y	Q15910	EZH2	O60674	JAK2	Y696	H689Y	689	Missense	distal	-7	no	5.619	6.094	EPSD	COSMIC	5.995	Gain
TK_Jak_JAK2_Y	Q15910	EZH2	O60674	JAK2	Y696	H689R	689	Missense	distal	-7	no	5.619	6.239	EPSD	COSMIC	5.995	Gain
TK_Jak_JAK2_Y	Q15910	EZH2	O60674	JAK2	Y696	V699L	699	Missense	distal	3	no	5.619	6.796	EPSD	COSMIC	5.995	Gain
TK_Jak_JAK2_Y	Q15910	EZH2	O60674	JAK2	Y696	M701V	701	Missense	distal	5	no	5.619	9.160	EPSD	COSMIC	5.995	Gain
TK_Jak_JAK2_Y	P42229	STAT5A	O60674	JAK2	Y683	P685H	685	Missense	proximal	2	no	6.063	6.821	EPSD	COSMIC	5.995	Up-regulation
TK_Jak_JAK2_Y	P42229	STAT5A	O60674	JAK2	Y683	Y682C	682	Missense	proximal	-1	no	6.063	5.876	EPSD	COSMIC	5.995	Loss
TK_Jak_JAK2_Y	P42229	STAT5A	O60674	JAK2	Y683	A688D	688	Missense	distal	5	no	6.063	8.756	EPSD	COSMIC	5.995	Up-regulation
TK_Jak_JAK2_Y	P42229	STAT5A	O60674	JAK2	Y694	A688D	688	Missense	distal	-6	no	12.625	12.872	PhosphoSitePlus	COSMIC	5.995	Up-regulation
TK_Jak_JAK2_Y	P41597	CCR2	O60674	JAK2	Y139	H144R	144	Missense	distal	5	no	9.206	9.396	PhosphoSitePlus	COSMIC	5.995	Up-regulation
TK_Jak_JAK2_Y	P41597	CCR2	O60674	JAK2	Y139	T135K	135	Missense	distal	-4	no	9.206	10.046	PhosphoSitePlus	COSMIC	5.995	Up-regulation
TK_Jak_JAK2_Y	P28482	MAPK1	O60674	JAK2	Y36	E33Q	33	Missense	distal	-3	no	5.286	7.457	EPSD	COSMIC	5.995	Gain
TK_Jak_JAK2_Y	P28482	MAPK1	O60674	JAK2	Y36	G34D	34	Missense	proximal	-2	no	5.286	8.995	EPSD	COSMIC	5.995	Gain
TK_Jak_JAK2_Y	P28482	MAPK1	O60674	JAK2	Y187	F183S	183	Missense	distal	-4	no	12.522	12.807	PhosphoSitePlus	COSMIC	5.995	Up-regulation
TK_Jak_JAK2_Y	P40763	STAT3	O60674	JAK2	Y657	A662V	662	Missense	distal	5	no	4.355	7.880	EPSD	COSMIC	5.995	Gain
TK_Jak_JAK2_Y	P40763	STAT3	O60674	JAK2	Y705	D698N	698	Missense	distal	-7	no	10.032	11.072	PhosphoSitePlus	COSMIC	5.995	Up-regulation
TK_Jak_JAK2_Y	P40763	STAT3	O60674	JAK2	Y705	G700R	700	Missense	distal	-5	no	10.032	10.021	PhosphoSitePlus	COSMIC	5.995	Down-regulation
TK_Jak_JAK2_Y	P40763	STAT3	O60674	JAK2	Y705	I711L	711	Missense	distal	6	no	10.032	9.584	PhosphoSitePlus	COSMIC	5.995	Down-regulation
TK_Jak_JAK2_Y	Q15118	PDK1	O60674	JAK2	Y243	R238H	238	Missense	distal	-5	no	9.334	9.424	PhosphoSitePlus	COSMIC	5.995	Up-regulation
TK_Jak_JAK2_Y	Q15118	PDK1	O60674	JAK2	Y243	A236D	236	Missense	distal	-7	no	9.334	9.124	PhosphoSitePlus	COSMIC	5.995	Down-regulation
TK_Jak_JAK2_Y	Q15118	PDK1	O60674	JAK2	Y268	H272Y	272	Missense	distal	4	no	6.139	5.111	EPSD	COSMIC	5.995	Loss
TK_Jak_JAK2_Y	Q15118	PDK1	O60674	JAK2	Y268	H272R	272	Missense	distal	4	no	6.139	5.268	EPSD	COSMIC	5.995	Loss
TK_Jak_JAK2_Y	Q15118	PDK1	O60674	JAK2	Y403	P401L	401	Missense	proximal	-2	no	6.722	4.656	EPSD	COSMIC	5.995	Loss
TK_Jak_JAK2_Y	P27361	MAPK3	O60674	JAK2	Y204	G199D	199	Missense	distal	-5	no	13.438	13.477	PhosphoSitePlus	COSMIC	5.995	Up-regulation
TK_Jak_JAK2_Y	P27361	MAPK3	O60674	JAK2	Y204	R211Q	211	Missense	distal	7	no	13.438	13.138	PhosphoSitePlus	COSMIC	5.995	Down-regulation
TK_Jak_JAK2_Y	P27361	MAPK3	O60674	JAK2	Y204	R211P	211	Missense	distal	7	no	13.438	13.403	PhosphoSitePlus	COSMIC	5.995	Down-regulation
TK_Jak_JAK2_Y	P27361	MAPK3	O60674	JAK2	Y204	T202M	202	Missense	proximal	-2	no	13.438	15.150	PhosphoSitePlus	COSMIC	5.995	Up-regulation
TK_Jak_JAK2_Y	P27361	MAPK3	O60674	JAK2	Y204	Y204C	204	Missense	central	0	yes	13.438	0.000	PhosphoSitePlus	COSMIC	5.995	Loss
TK_Jak_JAK2_Y	P27361	MAPK3	O60674	JAK2	Y204	L201P	201	Missense	distal	-3	no	13.438	14.835	PhosphoSitePlus	COSMIC	5.995	Up-regulation
TK_Jak_JAK2_Y	Q9UQC2	GAB2	O60674	JAK2	Y48	D52N	52	Missense	distal	4	no	6.170	5.637	EPSD	COSMIC;GDSC;CCLE	5.995	Loss
TK_Jak_JAK2_Y	Q9UQC2	GAB2	O60674	JAK2	Y614	T609I	609	Missense	distal	-5	no	7.068	7.082	EPSD	COSMIC	5.995	Up-regulation
TK_Jak_JAK2_Y	Q9UQC2	GAB2	O60674	JAK2	Y614	Q620P	620	Missense	distal	6	no	7.068	6.829	EPSD	COSMIC	5.995	Down-regulation
TK_Jak_JAK2_Y	Q9UQC2	GAB2	O60674	JAK2	Y643	K650R	650	Missense	distal	7	no	9.463	9.565	PhosphoSitePlus	COSMIC	5.995	Up-regulation
TK_Jak_JAK2_Y	Q9UQC2	GAB2	O60674	JAK2	Y643	Q645E	645	Missense	proximal	2	no	9.463	8.858	PhosphoSitePlus	COSMIC	5.995	Down-regulation
TK_Jak_JAK2_Y	Q99683	MAP3K5	O60674	JAK2	Y718	Q720E	720	Missense	proximal	2	no	10.831	10.226	PhosphoSitePlus	COSMIC	5.995	Down-regulation
TK_Jak_JAK2_Y	Q99683	MAP3K5	O60674	JAK2	Y718	R714K	714	Missense	distal	-4	no	10.831	11.071	PhosphoSitePlus	COSMIC	5.995	Up-regulation
TK_Jak_JAK2_Y	Q99683	MAP3K5	O60674	JAK2	Y982	G983C	983	Missense	proximal	1	no	6.315	6.182	EPSD	COSMIC	5.995	Down-regulation
TK_Jak_JAK2_Y	Q99683	MAP3K5	O60674	JAK2	Y982	E981D	981	Missense	proximal	-1	no	6.315	6.176	EPSD	COSMIC	5.995	Down-regulation
TK_Jak_JAK2_Y	Q99683	MAP3K5	O60674	JAK2	Y982	S986L	986	Missense	distal	4	no	6.315	6.231	EPSD	COSMIC	5.995	Down-regulation
TK_Jak_JAK2_Y	Q99683	MAP3K5	O60674	JAK2	Y982	G983S	983	Missense	proximal	1	no	6.315	6.146	EPSD	COSMIC;GDSC;CCLE	5.995	Down-regulation
TK_Jak_JAK2_Y	P42224	STAT1	O60674	JAK2	Y68	E74K	74	Missense	distal	6	no	5.598	6.341	EPSD	COSMIC	5.995	Gain
TK_Jak_JAK2_Y	P42224	STAT1	O60674	JAK2	Y170	D168H	168	Missense	proximal	-2	no	6.275	4.487	EPSD	COSMIC	5.995	Loss
TK_Jak_JAK2_Y	P42224	STAT1	O60674	JAK2	Y170	F172L	172	Missense	proximal	2	no	6.275	7.402	EPSD	COSMIC	5.995	Up-regulation
TK_Jak_JAK2_Y	P42224	STAT1	O60674	JAK2	Y203	Q196R	196	Missense	distal	-7	no	6.335	7.031	EPSD	COSMIC	5.995	Up-regulation
TK_Jak_JAK2_Y	P42224	STAT1	O60674	JAK2	Y701	D694N	694	Missense	distal	-7	no	8.804	9.843	PhosphoSitePlus	COSMIC	5.995	Up-regulation
TK_Jak_JAK2_Y	P42224	STAT1	O60674	JAK2	Y701	K697I	697	Missense	distal	-4	no	8.804	8.182	PhosphoSitePlus	COSMIC	5.995	Down-regulation
CMGC_CDK_CDK4_CDK4_ST	Q8IZL8	PELP1	P11802	CDK4	T49	P55T	55	Missense	distal	6	no	2.657	2.693	EPSD	COSMIC	2.642	Up-regulation
CMGC_CDK_CDK4_CDK4_ST	Q8IZL8	PELP1	P11802	CDK4	T49	R48L	48	Missense	proximal	-1	no	2.657	2.798	EPSD	COSMIC	2.642	Up-regulation
CMGC_CDK_CDK4_CDK4_ST	Q8IZL8	PELP1	P11802	CDK4	S477	P478Q	478	Missense	proximal	1	no	9.117	1.948	PhosphoSitePlus	COSMIC	2.642	Loss
CMGC_CDK_CDK4_CDK4_ST	Q8IZL8	PELP1	P11802	CDK4	S477	D471A	471	Missense	distal	-6	no	9.117	8.883	PhosphoSitePlus	COSMIC	2.642	Down-regulation
CMGC_CDK_CDK4_CDK4_ST	Q8IZL8	PELP1	P11802	CDK4	S481	P478Q	478	Missense	distal	-3	no	6.901	7.116	EPSD	COSMIC	2.642	Up-regulation
CMGC_CDK_CDK4_CDK4_ST	Q8IZL8	PELP1	P11802	CDK4	T488	P491S	491	Missense	distal	3	no	3.657	3.353	EPSD	COSMIC	2.642	Down-regulation
CMGC_CDK_CDK4_CDK4_ST	Q8IZL8	PELP1	P11802	CDK4	T488	P494H	494	Missense	distal	6	no	3.657	3.630	EPSD	COSMIC	2.642	Down-regulation
CMGC_CDK_CDK4_CDK4_ST	Q8IZL8	PELP1	P11802	CDK4	T488	P494T	494	Missense	distal	6	no	3.657	3.693	EPSD	COSMIC	2.642	Up-regulation
CMGC_CDK_CDK4_CDK4_ST	Q8IZL8	PELP1	P11802	CDK4	S492	P491S	491	Missense	proximal	-1	no	2.911	2.663	EPSD	COSMIC	2.642	Down-regulation
CMGC_CDK_CDK4_CDK4_ST	Q8IZL8	PELP1	P11802	CDK4	S492	P494H	494	Missense	proximal	2	no	2.911	2.821	EPSD	COSMIC	2.642	Down-regulation
CMGC_CDK_CDK4_CDK4_ST	Q8IZL8	PELP1	P11802	CDK4	S492	P494T	494	Missense	proximal	2	no	2.911	2.881	EPSD	COSMIC	2.642	Down-regulation
CMGC_CDK_CDK4_CDK4_ST	Q8IZL8	PELP1	P11802	CDK4	S515	H510N	510	Missense	distal	-5	no	2.639	2.677	EPSD	COSMIC	2.642	Gain
CMGC_CDK_CDK4_CDK4_ST	Q8IZL8	PELP1	P11802	CDK4	T647	P643H	643	Missense	distal	-4	no	9.108	9.109	EPSD	COSMIC	2.642	Up-regulation
CMGC_CDK_CDK4_CDK4_ST	Q8IZL8	PELP1	P11802	CDK4	T647	P648A	648	Missense	proximal	1	no	9.108	2.170	EPSD	COSMIC	2.642	Loss
CMGC_CDK_CDK4_CDK4_ST	Q8IZL8	PELP1	P11802	CDK4	T647	P640L	640	Missense	distal	-7	no	9.108	8.628	EPSD	COSMIC	2.642	Down-regulation
CMGC_CDK_CDK4_CDK4_ST	Q8IZL8	PELP1	P11802	CDK4	S658	F660S	660	Missense	proximal	2	no	7.514	7.815	EPSD	COSMIC	2.642	Up-regulation
CMGC_CDK_CDK4_CDK4_ST	Q8IZL8	PELP1	P11802	CDK4	S658	P664L	664	Missense	distal	6	no	7.514	7.492	EPSD	COSMIC	2.642	Down-regulation
CMGC_CDK_CDK4_CDK4_ST	Q8IZL8	PELP1	P11802	CDK4	S658	E655K	655	Missense	distal	-3	no	7.514	7.484	EPSD	COSMIC	2.642	Down-regulation
CMGC_CDK_CDK4_CDK4_ST	Q8IZL8	PELP1	P11802	CDK4	S743	P742S	742	Missense	proximal	-1	no	2.730	2.482	EPSD	COSMIC	2.642	Loss
CMGC_CDK_CDK4_CDK4_ST	Q8IZL8	PELP1	P11802	CDK4	S743	L740F	740	Missense	distal	-3	no	2.730	2.695	EPSD	COSMIC	2.642	Down-regulation
CMGC_CDK_CDK4_CDK4_ST	Q8IZL8	PELP1	P11802	CDK4	S743	G744R	744	Missense	proximal	1	no	2.730	1.745	EPSD	COSMIC	2.642	Loss
CMGC_CDK_CDK4_CDK4_ST	Q8IZL8	PELP1	P11802	CDK4	T745	P742S	742	Missense	distal	-3	no	8.700	8.775	EPSD	COSMIC	2.642	Up-regulation
CMGC_CDK_CDK4_CDK4_ST	Q8IZL8	PELP1	P11802	CDK4	T745	L740F	740	Missense	distal	-5	no	8.700	8.686	EPSD	COSMIC	2.642	Down-regulation
CMGC_CDK_CDK4_CDK4_ST	Q8IZL8	PELP1	P11802	CDK4	T745	G744R	744	Missense	proximal	-1	no	8.700	8.329	EPSD	COSMIC	2.642	Down-regulation
CMGC_CDK_CDK4_CDK4_ST	Q8IZL8	PELP1	P11802	CDK4	T745	I739T	739	Missense	distal	-6	no	8.700	8.521	EPSD	COSMIC	2.642	Down-regulation
CMGC_CDK_CDK4_CDK4_ST	Q8IZL8	PELP1	P11802	CDK4	S804	L798P	798	Missense	distal	-6	no	2.648	2.495	EPSD	COSMIC	2.642	Loss
CMGC_CDK_CDK4_CDK4_ST	Q8IZL8	PELP1	P11802	CDK4	S804	L798M	798	Missense	distal	-6	no	2.648	2.605	EPSD	COSMIC	2.642	Loss
CMGC_CDK_CDK4_CDK4_ST	Q8IZL8	PELP1	P11802	CDK4	S804	P808Q	808	Missense	distal	4	no	2.648	2.739	EPSD	COSMIC	2.642	Up-regulation
CMGC_CDK_CDK4_CDK4_ST	Q8IZL8	PELP1	P11802	CDK4	S804	G805V	805	Missense	proximal	1	no	2.648	1.120	EPSD	COSMIC	2.642	Loss
CMGC_CDK_CDK4_CDK4_ST	Q8IZL8	PELP1	P11802	CDK4	T807	P808Q	808	Missense	proximal	1	no	9.033	1.864	EPSD	COSMIC	2.642	Loss
CMGC_CDK_CDK4_CDK4_ST	Q8IZL8	PELP1	P11802	CDK4	T807	G805V	805	Missense	proximal	-2	no	9.033	9.002	EPSD	COSMIC	2.642	Down-regulation
CMGC_CDK_CDK4_CDK4_ST	Q8IZL8	PELP1	P11802	CDK4	S991	A985P	985	Missense	distal	-6	no	9.416	9.525	EPSD	COSMIC	2.642	Up-regulation
CMGC_CDK_CDK4_CDK4_ST	Q8IZL8	PELP1	P11802	CDK4	S991	A985T	985	Missense	distal	-6	no	9.416	9.503	EPSD	COSMIC	2.642	Up-regulation
CMGC_CDK_CDK4_CDK4_ST	Q8IZL8	PELP1	P11802	CDK4	S991	E998Q	998	Missense	distal	7	no	9.416	9.410	EPSD	COSMIC	2.642	Down-regulation
CMGC_CDK_CDK4_CDK4_ST	Q8IZL8	PELP1	P11802	CDK4	S1043	G1047E	1047	Missense	distal	4	no	8.513	8.171	EPSD	COSMIC	2.642	Down-regulation
CMGC_CDK_CDK4_CDK4_ST	Q8IZL8	PELP1	P11802	CDK4	S1043	G1041V	1041	Missense	proximal	-2	no	8.513	8.482	EPSD	COSMIC	2.642	Down-regulation
CMGC_CDK_CDK4_CDK4_ST	Q8IZL8	PELP1	P11802	CDK4	S1043	P1050S	1050	Missense	distal	7	no	8.513	8.521	EPSD	COSMIC	2.642	Up-regulation
CMGC_CDK_CDK4_CDK4_ST	Q8IZL8	PELP1	P11802	CDK4	S1043	E1036K	1036	Missense	distal	-7	no	8.513	8.468	EPSD	COSMIC	2.642	Down-regulation
CMGC_CDK_CDK4_CDK4_ST	Q8IZL8	PELP1	P11802	CDK4	S1043	E1040V	1040	Missense	distal	-3	no	8.513	8.576	EPSD	COSMIC	2.642	Up-regulation
CMGC_CDK_CDK4_CDK4_ST	Q8IZL8	PELP1	P11802	CDK4	T1082	P1078L	1078	Missense	distal	-4	no	6.998	7.000	EPSD	COSMIC	2.642	Up-regulation
CMGC_CDK_CDK4_CDK4_ST	Q8IZL8	PELP1	P11802	CDK4	T1082	E1087Q	1087	Missense	distal	5	no	6.998	7.002	EPSD	COSMIC;CCLE	2.642	Up-regulation
CMGC_CDK_CDK4_CDK4_ST	Q8IZL8	PELP1	P11802	CDK4	T1082	E1086K	1086	Missense	distal	4	no	6.998	6.948	EPSD	COSMIC	2.642	Down-regulation
CMGC_CDK_CDK4_CDK4_ST	P06400	RB1	P11802	CDK4	T5	P6S	6	Missense	proximal	1	no	7.270	1.082	EPSD	COSMIC	2.642	Loss
CMGC_CDK_CDK4_CDK4_ST	P06400	RB1	P11802	CDK4	T5	P2S	2	Missense	distal	-3	no	7.270	7.344	EPSD	COSMIC	2.642	Up-regulation
CMGC_CDK_CDK4_CDK4_ST	P06400	RB1	P11802	CDK4	T5	T5N	5	Missense	central	0	yes	7.270	0.000	EPSD	COSMIC	2.642	Loss
CMGC_CDK_CDK4_CDK4_ST	P06400	RB1	P11802	CDK4	T5	R7Q	7	Missense	proximal	2	no	7.270	7.162	EPSD	COSMIC	2.642	Down-regulation
CMGC_CDK_CDK4_CDK4_ST	P06400	RB1	P11802	CDK4	S230	K228R	228	Missense	proximal	-2	no	7.809	7.792	EPSD	COSMIC;GDSC;CCLE	2.642	Down-regulation
CMGC_CDK_CDK4_CDK4_ST	P06400	RB1	P11802	CDK4	S230	I227N	227	Missense	distal	-3	no	7.809	7.724	EPSD	COSMIC	2.642	Down-regulation
CMGC_CDK_CDK4_CDK4_ST	P06400	RB1	P11802	CDK4	S230	P232L	232	Missense	proximal	2	no	7.809	7.741	EPSD	COSMIC	2.642	Down-regulation
CMGC_CDK_CDK4_CDK4_ST	P06400	RB1	P11802	CDK4	S249	V243A	243	Missense	distal	-6	no	8.504	8.249	EPSD	COSMIC	2.642	Down-regulation
CMGC_CDK_CDK4_CDK4_ST	P06400	RB1	P11802	CDK4	S249	P250S	250	Missense	proximal	1	no	8.504	2.317	EPSD	COSMIC	2.642	Loss
CMGC_CDK_CDK4_CDK4_ST	P06400	RB1	P11802	CDK4	T252	Q257R	257	Missense	distal	5	no	8.096	8.088	EPSD;PhosphoSitePlus	COSMIC	2.642	Down-regulation
CMGC_CDK_CDK4_CDK4_ST	P06400	RB1	P11802	CDK4	T252	P250S	250	Missense	proximal	-2	no	8.096	7.791	EPSD;PhosphoSitePlus	COSMIC	2.642	Down-regulation
CMGC_CDK_CDK4_CDK4_ST	P06400	RB1	P11802	CDK4	T356	R358Q	358	Missense	proximal	2	no	7.068	6.960	EPSD;PhosphoSitePlus	COSMIC;CCLE	2.642	Down-regulation
CMGC_CDK_CDK4_CDK4_ST	P06400	RB1	P11802	CDK4	T356	N361Y	361	Missense	distal	5	no	7.068	7.076	EPSD;PhosphoSitePlus	COSMIC	2.642	Up-regulation
CMGC_CDK_CDK4_CDK4_ST	P06400	RB1	P11802	CDK4	T373	P370S	370	Missense	distal	-3	no	7.816	7.891	EPSD;PhosphoSitePlus	COSMIC	2.642	Up-regulation
CMGC_CDK_CDK4_CDK4_ST	P06400	RB1	P11802	CDK4	T373	P374L	374	Missense	proximal	1	no	7.816	0.237	EPSD;PhosphoSitePlus	COSMIC	2.642	Loss
CMGC_CDK_CDK4_CDK4_ST	P06400	RB1	P11802	CDK4	T373	N367D	367	Missense	distal	-6	no	7.816	7.938	EPSD;PhosphoSitePlus	COSMIC	2.642	Up-regulation
CMGC_CDK_CDK4_CDK4_ST	P06400	RB1	P11802	CDK4	T373	P370L	370	Missense	distal	-3	no	7.816	8.074	EPSD;PhosphoSitePlus	COSMIC	2.642	Up-regulation
CMGC_CDK_CDK4_CDK4_ST	P06400	RB1	P11802	CDK4	S567	S560P	560	Missense	distal	-7	no	8.961	8.760	EPSD	COSMIC	2.642	Down-regulation
CMGC_CDK_CDK4_CDK4_ST	P06400	RB1	P11802	CDK4	S567	L564V	564	Missense	distal	-3	no	8.961	8.954	EPSD	COSMIC	2.642	Down-regulation
CMGC_CDK_CDK4_CDK4_ST	P06400	RB1	P11802	CDK4	S567	L572F	572	Missense	distal	5	no	8.961	8.957	EPSD	COSMIC	2.642	Down-regulation
CMGC_CDK_CDK4_CDK4_ST	P06400	RB1	P11802	CDK4	S608	R611S	611	Missense	distal	3	no	8.292	8.534	EPSD;PhosphoSitePlus	COSMIC	2.642	Up-regulation
CMGC_CDK_CDK4_CDK4_ST	P06400	RB1	P11802	CDK4	S608	S612P	612	Missense	distal	4	no	8.292	8.499	EPSD;PhosphoSitePlus	COSMIC	2.642	Up-regulation
CMGC_CDK_CDK4_CDK4_ST	P06400	RB1	P11802	CDK4	S608	Y606C	606	Missense	proximal	-2	no	8.292	8.243	EPSD;PhosphoSitePlus	COSMIC	2.642	Down-regulation
CMGC_CDK_CDK4_CDK4_ST	P06400	RB1	P11802	CDK4	S608	P609S	609	Missense	proximal	1	no	8.292	2.105	EPSD;PhosphoSitePlus	COSMIC	2.642	Loss
CMGC_CDK_CDK4_CDK4_ST	P06400	RB1	P11802	CDK4	S608	M605T	605	Missense	distal	-3	no	8.292	8.234	EPSD;PhosphoSitePlus	COSMIC	2.642	Down-regulation
CMGC_CDK_CDK4_CDK4_ST	P06400	RB1	P11802	CDK4	S608	L607V	607	Missense	proximal	-1	no	8.292	8.321	EPSD;PhosphoSitePlus	COSMIC	2.642	Up-regulation
CMGC_CDK_CDK4_CDK4_ST	P06400	RB1	P11802	CDK4	S608	L607I	607	Missense	proximal	-1	no	8.292	8.320	EPSD;PhosphoSitePlus	COSMIC	2.642	Up-regulation
CMGC_CDK_CDK4_CDK4_ST	P06400	RB1	P11802	CDK4	S612	R611S	611	Missense	proximal	-1	no	8.583	8.438	EPSD;PhosphoSitePlus	COSMIC	2.642	Down-regulation
CMGC_CDK_CDK4_CDK4_ST	P06400	RB1	P11802	CDK4	S612	S612P	612	Missense	central	0	yes	8.583	0.000	EPSD;PhosphoSitePlus	COSMIC	2.642	Loss
CMGC_CDK_CDK4_CDK4_ST	P06400	RB1	P11802	CDK4	S612	Y606C	606	Missense	distal	-6	no	8.583	8.662	EPSD;PhosphoSitePlus	COSMIC	2.642	Up-regulation
CMGC_CDK_CDK4_CDK4_ST	P06400	RB1	P11802	CDK4	S612	P609S	609	Missense	distal	-3	no	8.583	8.658	EPSD;PhosphoSitePlus	COSMIC	2.642	Up-regulation
CMGC_CDK_CDK4_CDK4_ST	P06400	RB1	P11802	CDK4	S612	M605T	605	Missense	distal	-7	no	8.583	8.797	EPSD;PhosphoSitePlus	COSMIC	2.642	Up-regulation
CMGC_CDK_CDK4_CDK4_ST	P06400	RB1	P11802	CDK4	S612	L607V	607	Missense	distal	-5	no	8.583	8.592	EPSD;PhosphoSitePlus	COSMIC	2.642	Up-regulation
CMGC_CDK_CDK4_CDK4_ST	P06400	RB1	P11802	CDK4	S612	L607I	607	Missense	distal	-5	no	8.583	8.598	EPSD;PhosphoSitePlus	COSMIC	2.642	Up-regulation
CMGC_CDK_CDK4_CDK4_ST	P06400	RB1	P11802	CDK4	T620	R621P	621	Missense	proximal	1	no	-0.136	6.651	EPSD	COSMIC	2.642	Gain
CMGC_CDK_CDK4_CDK4_ST	P06400	RB1	P11802	CDK4	T633	S634P	634	Missense	proximal	1	no	1.432	7.619	EPSD	COSMIC	2.642	Gain
CMGC_CDK_CDK4_CDK4_ST	P06400	RB1	P11802	CDK4	S780	H784Y	784	Missense	distal	4	no	8.334	8.292	PhosphoSitePlus;EPSD	COSMIC	2.642	Down-regulation
CMGC_CDK_CDK4_CDK4_ST	P06400	RB1	P11802	CDK4	S780	P777S	777	Missense	distal	-3	no	8.334	8.408	PhosphoSitePlus;EPSD	COSMIC	2.642	Up-regulation
CMGC_CDK_CDK4_CDK4_ST	P06400	RB1	P11802	CDK4	S780	P786S	786	Missense	distal	6	no	8.334	8.491	PhosphoSitePlus;EPSD	COSMIC	2.642	Up-regulation
CMGC_CDK_CDK4_CDK4_ST	P06400	RB1	P11802	CDK4	S780	S773F	773	Missense	distal	-7	no	8.334	7.621	PhosphoSitePlus;EPSD	COSMIC	2.642	Down-regulation
CMGC_CDK_CDK4_CDK4_ST	P06400	RB1	P11802	CDK4	S788	S795L	795	Missense	distal	7	no	9.839	9.814	EPSD;PhosphoSitePlus	COSMIC	2.642	Down-regulation
CMGC_CDK_CDK4_CDK4_ST	P06400	RB1	P11802	CDK4	S788	S794I	794	Missense	distal	6	no	9.839	9.642	EPSD;PhosphoSitePlus	COSMIC	2.642	Down-regulation
CMGC_CDK_CDK4_CDK4_ST	P06400	RB1	P11802	CDK4	S788	P786S	786	Missense	proximal	-2	no	9.839	9.534	EPSD;PhosphoSitePlus	COSMIC	2.642	Down-regulation
CMGC_CDK_CDK4_CDK4_ST	P06400	RB1	P11802	CDK4	S788	P793S	793	Missense	distal	5	no	9.839	9.853	EPSD;PhosphoSitePlus	COSMIC;CCLE	2.642	Up-regulation
CMGC_CDK_CDK4_CDK4_ST	P06400	RB1	P11802	CDK4	S795	S795L	795	Missense	central	0	yes	8.275	0.000	EPSD;PhosphoSitePlus	COSMIC	2.642	Loss
CMGC_CDK_CDK4_CDK4_ST	P06400	RB1	P11802	CDK4	S795	G802R	802	Missense	distal	7	no	8.275	8.294	EPSD;PhosphoSitePlus	COSMIC	2.642	Up-regulation
CMGC_CDK_CDK4_CDK4_ST	P06400	RB1	P11802	CDK4	S795	R798Q	798	Missense	distal	3	no	8.275	7.926	EPSD;PhosphoSitePlus	COSMIC;GDSC;CCLE	2.642	Down-regulation
CMGC_CDK_CDK4_CDK4_ST	P06400	RB1	P11802	CDK4	S795	S794I	794	Missense	proximal	-1	no	8.275	8.587	EPSD;PhosphoSitePlus	COSMIC	2.642	Up-regulation
CMGC_CDK_CDK4_CDK4_ST	P06400	RB1	P11802	CDK4	S795	G801A	801	Missense	distal	6	no	8.275	8.493	EPSD;PhosphoSitePlus	COSMIC	2.642	Up-regulation
CMGC_CDK_CDK4_CDK4_ST	P06400	RB1	P11802	CDK4	S795	P793S	793	Missense	proximal	-2	no	8.275	7.970	EPSD;PhosphoSitePlus	COSMIC;CCLE	2.642	Down-regulation
CMGC_CDK_CDK4_CDK4_ST	P06400	RB1	P11802	CDK4	S807	G802R	802	Missense	distal	-5	no	8.321	8.440	EPSD;PhosphoSitePlus	COSMIC	2.642	Up-regulation
CMGC_CDK_CDK4_CDK4_ST	P06400	RB1	P11802	CDK4	S807	K814T	814	Missense	distal	7	no	8.321	8.317	EPSD;PhosphoSitePlus	COSMIC	2.642	Down-regulation
CMGC_CDK_CDK4_CDK4_ST	P06400	RB1	P11802	CDK4	S807	G801A	801	Missense	distal	-6	no	8.321	7.874	EPSD;PhosphoSitePlus	COSMIC	2.642	Down-regulation
CMGC_CDK_CDK4_CDK4_ST	P06400	RB1	P11802	CDK4	S811	G818S	818	Missense	distal	7	no	7.849	7.883	EPSD;PhosphoSitePlus	COSMIC	2.642	Up-regulation
CMGC_CDK_CDK4_CDK4_ST	P06400	RB1	P11802	CDK4	S811	G818C	818	Missense	distal	7	no	7.849	7.858	EPSD;PhosphoSitePlus	COSMIC	2.642	Up-regulation
CMGC_CDK_CDK4_CDK4_ST	P06400	RB1	P11802	CDK4	S811	K814T	814	Missense	distal	3	no	7.849	7.593	EPSD;PhosphoSitePlus	COSMIC	2.642	Down-regulation
CMGC_CDK_CDK4_CDK4_ST	P06400	RB1	P11802	CDK4	T821	G818S	818	Missense	distal	-3	no	6.539	6.317	EPSD	COSMIC	2.642	Down-regulation
CMGC_CDK_CDK4_CDK4_ST	P06400	RB1	P11802	CDK4	T821	P822S	822	Missense	proximal	1	no	6.539	0.352	EPSD	COSMIC	2.642	Loss
CMGC_CDK_CDK4_CDK4_ST	P06400	RB1	P11802	CDK4	T821	G818C	818	Missense	distal	-3	no	6.539	6.490	EPSD	COSMIC	2.642	Down-regulation
CMGC_CDK_CDK4_CDK4_ST	P06400	RB1	P11802	CDK4	T821	K814T	814	Missense	distal	-7	no	6.539	6.558	EPSD	COSMIC	2.642	Up-regulation
CMGC_CDK_CDK4_CDK4_ST	P06400	RB1	P11802	CDK4	T823	G818S	818	Missense	distal	-5	no	2.643	2.871	EPSD	COSMIC	2.642	Up-regulation
CMGC_CDK_CDK4_CDK4_ST	P06400	RB1	P11802	CDK4	T823	S829L	829	Missense	distal	6	no	2.643	2.464	EPSD	COSMIC	2.642	Loss
CMGC_CDK_CDK4_CDK4_ST	P06400	RB1	P11802	CDK4	T823	P822S	822	Missense	proximal	-1	no	2.643	2.395	EPSD	COSMIC	2.642	Loss
CMGC_CDK_CDK4_CDK4_ST	P06400	RB1	P11802	CDK4	T823	G818C	818	Missense	distal	-5	no	2.643	2.713	EPSD	COSMIC	2.642	Up-regulation
CMGC_CDK_CDK4_CDK4_ST	P06400	RB1	P11802	CDK4	T826	S829L	829	Missense	distal	3	no	9.039	8.445	EPSD;PhosphoSitePlus	COSMIC	2.642	Down-regulation
CMGC_CDK_CDK4_CDK4_ST	P06400	RB1	P11802	CDK4	T841	S842F	842	Missense	proximal	1	no	2.247	2.770	EPSD	COSMIC	2.642	Gain
CMGC_CDK_CDK4_CDK4_ST	Q08999	RBL2	P11802	CDK4	S40	Q44R	44	Missense	distal	4	no	8.516	8.449	EPSD	COSMIC	2.642	Down-regulation
CMGC_CDK_CDK4_CDK4_ST	Q08999	RBL2	P11802	CDK4	T42	Q44R	44	Missense	proximal	2	no	6.730	6.838	EPSD	COSMIC	2.642	Up-regulation
CMGC_CDK_CDK4_CDK4_ST	Q08999	RBL2	P11802	CDK4	T401	Y408C	408	Missense	distal	7	no	7.442	7.437	PhosphoSitePlus;EPSD	COSMIC	2.642	Down-regulation
CMGC_CDK_CDK4_CDK4_ST	Q08999	RBL2	P11802	CDK4	S413	P414L	414	Missense	proximal	1	no	7.836	0.256	EPSD	COSMIC	2.642	Loss
CMGC_CDK_CDK4_CDK4_ST	Q08999	RBL2	P11802	CDK4	S413	P414H	414	Missense	proximal	1	no	7.836	1.253	EPSD	COSMIC	2.642	Loss
CMGC_CDK_CDK4_CDK4_ST	Q08999	RBL2	P11802	CDK4	S413	S413R	413	Missense	central	0	yes	7.836	0.000	EPSD	COSMIC	2.642	Loss
CMGC_CDK_CDK4_CDK4_ST	Q08999	RBL2	P11802	CDK4	S413	Y408C	408	Missense	distal	-5	no	7.836	7.798	EPSD	COSMIC	2.642	Down-regulation
CMGC_CDK_CDK4_CDK4_ST	Q08999	RBL2	P11802	CDK4	T417	P414L	414	Missense	distal	-3	no	7.203	7.460	EPSD	COSMIC	2.642	Up-regulation
CMGC_CDK_CDK4_CDK4_ST	Q08999	RBL2	P11802	CDK4	T417	P414H	414	Missense	distal	-3	no	7.203	7.425	EPSD	COSMIC	2.642	Up-regulation
CMGC_CDK_CDK4_CDK4_ST	Q08999	RBL2	P11802	CDK4	T417	S413R	413	Missense	distal	-4	no	7.203	7.204	EPSD	COSMIC	2.642	Up-regulation
CMGC_CDK_CDK4_CDK4_ST	Q08999	RBL2	P11802	CDK4	T434	R428H	428	Missense	distal	-6	no	2.606	2.650	EPSD	COSMIC	2.642	Gain
CMGC_CDK_CDK4_CDK4_ST	Q08999	RBL2	P11802	CDK4	S603	W606C	606	Missense	distal	3	no	8.467	8.516	EPSD	COSMIC	2.642	Up-regulation
CMGC_CDK_CDK4_CDK4_ST	Q08999	RBL2	P11802	CDK4	S603	I609N	609	Missense	distal	6	no	8.467	8.525	EPSD	COSMIC	2.642	Up-regulation
CMGC_CDK_CDK4_CDK4_ST	Q08999	RBL2	P11802	CDK4	S639	P643S	643	Missense	distal	4	no	6.454	6.247	EPSD	COSMIC	2.642	Down-regulation
CMGC_CDK_CDK4_CDK4_ST	Q08999	RBL2	P11802	CDK4	T642	E648G	648	Missense	distal	6	no	8.457	8.291	EPSD	COSMIC	2.642	Down-regulation
CMGC_CDK_CDK4_CDK4_ST	Q08999	RBL2	P11802	CDK4	T642	P643S	643	Missense	proximal	1	no	8.457	2.270	EPSD	COSMIC	2.642	Loss
CMGC_CDK_CDK4_CDK4_ST	Q08999	RBL2	P11802	CDK4	S688	E685Q	685	Missense	distal	-3	no	7.073	7.100	EPSD	COSMIC	2.642	Up-regulation
CMGC_CDK_CDK4_CDK4_ST	Q08999	RBL2	P11802	CDK4	S688	T694M	694	Missense	distal	6	no	7.073	7.008	EPSD	COSMIC	2.642	Down-regulation
CMGC_CDK_CDK4_CDK4_ST	Q08999	RBL2	P11802	CDK4	T694	R697H	697	Missense	distal	3	no	6.552	6.185	EPSD	COSMIC	2.642	Down-regulation
CMGC_CDK_CDK4_CDK4_ST	Q08999	RBL2	P11802	CDK4	T694	P699S	699	Missense	distal	5	no	6.552	6.566	EPSD	COSMIC	2.642	Up-regulation
CMGC_CDK_CDK4_CDK4_ST	Q08999	RBL2	P11802	CDK4	T694	T694M	694	Missense	central	0	yes	6.552	0.000	EPSD	COSMIC	2.642	Loss
CMGC_CDK_CDK4_CDK4_ST	Q08999	RBL2	P11802	CDK4	S952	K958R	958	Missense	distal	6	no	8.031	8.011	EPSD	COSMIC	2.642	Down-regulation
CMGC_CDK_CDK4_CDK4_ST	Q08999	RBL2	P11802	CDK4	S952	S948G	948	Missense	distal	-4	no	8.031	8.033	EPSD	COSMIC	2.642	Up-regulation
CMGC_CDK_CDK4_CDK4_ST	Q08999	RBL2	P11802	CDK4	S966	R963T	963	Missense	distal	-3	no	8.353	8.348	EPSD	COSMIC	2.642	Down-regulation
CMGC_CDK_CDK4_CDK4_ST	Q08999	RBL2	P11802	CDK4	S966	S972G	972	Missense	distal	6	no	8.353	8.058	EPSD	COSMIC	2.642	Down-regulation
CMGC_CDK_CDK4_CDK4_ST	Q08999	RBL2	P11802	CDK4	S971	S972G	972	Missense	proximal	1	no	2.557	2.943	EPSD	COSMIC	2.642	Gain
CMGC_CDK_CDK4_CDK4_ST	Q08999	RBL2	P11802	CDK4	S973	S972G	972	Missense	proximal	-1	no	2.783	3.299	EPSD	COSMIC	2.642	Up-regulation
CMGC_CDK_CDK4_CDK4_ST	Q08999	RBL2	P11802	CDK4	T986	S982N	982	Missense	distal	-4	no	7.562	7.563	EPSD	COSMIC	2.642	Up-regulation
CMGC_CDK_CDK4_CDK4_ST	Q08999	RBL2	P11802	CDK4	S1035	S1035Y	1035	Missense	central	0	yes	8.592	0.000	EPSD;PhosphoSitePlus	COSMIC	2.642	Loss
CMGC_CDK_CDK4_CDK4_ST	Q08999	RBL2	P11802	CDK4	S1035	P1036L	1036	Missense	proximal	1	no	8.592	1.013	EPSD;PhosphoSitePlus	COSMIC;CCLE	2.642	Loss
CMGC_CDK_CDK4_CDK4_ST	Q08999	RBL2	P11802	CDK4	T1042	R1046H	1046	Missense	distal	4	no	2.898	3.017	EPSD	COSMIC	2.642	Up-regulation
CMGC_CDK_CDK4_CDK4_ST	Q08999	RBL2	P11802	CDK4	T1042	R1046C	1046	Missense	distal	4	no	2.898	3.062	EPSD	COSMIC	2.642	Up-regulation
CMGC_CDK_CDK4_CDK4_ST	Q08999	RBL2	P11802	CDK4	T1042	S1035Y	1035	Missense	distal	-7	no	2.898	2.301	EPSD	COSMIC	2.642	Loss
CMGC_CDK_CDK4_CDK4_ST	Q08999	RBL2	P11802	CDK4	T1042	I1048K	1048	Missense	distal	6	no	2.898	3.004	EPSD	COSMIC	2.642	Up-regulation
CMGC_CDK_CDK4_CDK4_ST	Q08999	RBL2	P11802	CDK4	T1042	P1036L	1036	Missense	distal	-6	no	2.898	3.050	EPSD	COSMIC;CCLE	2.642	Up-regulation
CMGC_CDK_CDK4_CDK4_ST	Q08999	RBL2	P11802	CDK4	T1042	S1044F	1044	Missense	proximal	2	no	2.898	2.597	EPSD	COSMIC	2.642	Loss
CMGC_CDK_CDK4_CDK4_ST	Q08999	RBL2	P11802	CDK4	T1042	R1047Q	1047	Missense	distal	5	no	2.898	2.906	EPSD	COSMIC	2.642	Up-regulation
CMGC_CDK_CDK4_CDK4_ST	Q08999	RBL2	P11802	CDK4	S1044	R1046H	1046	Missense	proximal	2	no	8.959	8.833	EPSD	COSMIC	2.642	Down-regulation
CMGC_CDK_CDK4_CDK4_ST	Q08999	RBL2	P11802	CDK4	S1044	R1046C	1046	Missense	proximal	2	no	8.959	8.785	EPSD	COSMIC	2.642	Down-regulation
CMGC_CDK_CDK4_CDK4_ST	Q08999	RBL2	P11802	CDK4	S1044	I1048K	1048	Missense	distal	4	no	8.959	8.746	EPSD	COSMIC	2.642	Down-regulation
CMGC_CDK_CDK4_CDK4_ST	Q08999	RBL2	P11802	CDK4	S1044	S1044F	1044	Missense	central	0	yes	8.959	0.000	EPSD	COSMIC	2.642	Loss
CMGC_CDK_CDK4_CDK4_ST	Q08999	RBL2	P11802	CDK4	S1044	R1047Q	1047	Missense	distal	3	no	8.959	8.611	EPSD	COSMIC	2.642	Down-regulation
CMGC_CDK_CDK4_CDK4_ST	Q08999	RBL2	P11802	CDK4	S1059	T1065K	1065	Missense	distal	6	no	6.427	6.458	EPSD	COSMIC	2.642	Up-regulation
CMGC_CDK_CDK4_CDK4_ST	Q08999	RBL2	P11802	CDK4	S1059	H1061Q	1061	Missense	proximal	2	no	6.427	6.445	EPSD	COSMIC	2.642	Up-regulation
CMGC_CDK_CDK4_CDK4_ST	Q08999	RBL2	P11802	CDK4	S1068	T1065K	1065	Missense	distal	-3	no	6.398	6.382	EPSD	COSMIC	2.642	Down-regulation
CMGC_CDK_CDK4_CDK4_ST	Q08999	RBL2	P11802	CDK4	S1068	H1061Q	1061	Missense	distal	-7	no	6.398	6.488	EPSD	COSMIC	2.642	Up-regulation
CMGC_CDK_CDK4_CDK4_ST	Q08999	RBL2	P11802	CDK4	S1080	K1083N	1083	Missense	distal	3	no	7.198	6.984	EPSD	COSMIC	2.642	Down-regulation
CMGC_CDK_CDK4_CDK4_ST	Q08999	RBL2	P11802	CDK4	T1097	K1100N	1100	Missense	distal	3	no	7.515	7.300	EPSD	COSMIC	2.642	Down-regulation
CMGC_CDK_CDK4_CDK4_ST	Q08999	RBL2	P11802	CDK4	T1097	S1090I	1090	Missense	distal	-7	no	7.515	6.870	EPSD	COSMIC	2.642	Down-regulation
CMGC_CDK_CDK4_CDK4_ST	Q08999	RBL2	P11802	CDK4	T1097	I1092M	1092	Missense	distal	-5	no	7.515	7.524	EPSD	COSMIC	2.642	Up-regulation
CMGC_CDK_CDK4_CDK4_ST	Q08999	RBL2	P11802	CDK4	S1112	L1106F	1106	Missense	distal	-6	no	8.786	8.791	EPSD	COSMIC	2.642	Up-regulation
CMGC_CDK_CDK4_CDK4_ST	Q08999	RBL2	P11802	CDK4	S1112	P1113S	1113	Missense	proximal	1	no	8.786	2.598	EPSD	COSMIC	2.642	Loss
CMGC_CDK_CDK4_CDK4_ST	Q08050	FOXM1	P11802	CDK4	S4	R6S	6	Missense	proximal	2	no	8.427	8.549	EPSD;PhosphoSitePlus	COSMIC	2.642	Up-regulation
CMGC_CDK_CDK4_CDK4_ST	Q08050	FOXM1	P11802	CDK4	S331	F324L	324	Missense	distal	-7	no	8.282	8.315	EPSD	COSMIC;GDSC;CCLE	2.642	Up-regulation
CMGC_CDK_CDK4_CDK4_ST	Q08050	FOXM1	P11802	CDK4	S331	P332A	332	Missense	proximal	1	no	8.282	1.344	EPSD	COSMIC	2.642	Loss
CMGC_CDK_CDK4_CDK4_ST	Q08050	FOXM1	P11802	CDK4	S451	E448K	448	Missense	distal	-3	no	8.950	8.921	EPSD;PhosphoSitePlus	COSMIC	2.642	Down-regulation
CMGC_CDK_CDK4_CDK4_ST	Q08050	FOXM1	P11802	CDK4	S451	P455L	455	Missense	distal	4	no	8.950	9.111	EPSD;PhosphoSitePlus	COSMIC	2.642	Up-regulation
CMGC_CDK_CDK4_CDK4_ST	Q08050	FOXM1	P11802	CDK4	S451	P455S	455	Missense	distal	4	no	8.950	8.744	EPSD;PhosphoSitePlus	COSMIC	2.642	Down-regulation
CMGC_CDK_CDK4_CDK4_ST	Q08050	FOXM1	P11802	CDK4	S451	F450L	450	Missense	proximal	-1	no	8.950	8.868	EPSD;PhosphoSitePlus	COSMIC	2.642	Down-regulation
CMGC_CDK_CDK4_CDK4_ST	Q08050	FOXM1	P11802	CDK4	S481	E486Q	486	Missense	distal	5	no	8.459	8.463	EPSD	COSMIC	2.642	Up-regulation
CMGC_CDK_CDK4_CDK4_ST	Q08050	FOXM1	P11802	CDK4	S481	R475T	475	Missense	distal	-6	no	8.459	8.376	EPSD	COSMIC	2.642	Down-regulation
CMGC_CDK_CDK4_CDK4_ST	Q08050	FOXM1	P11802	CDK4	S481	E480K	480	Missense	proximal	-1	no	8.459	8.368	EPSD	COSMIC	2.642	Down-regulation
CMGC_CDK_CDK4_CDK4_ST	Q08050	FOXM1	P11802	CDK4	S489	E486Q	486	Missense	distal	-3	no	8.526	8.554	EPSD;PhosphoSitePlus	COSMIC	2.642	Up-regulation
CMGC_CDK_CDK4_CDK4_ST	Q08050	FOXM1	P11802	CDK4	S489	P492L	492	Missense	distal	3	no	8.526	7.628	EPSD;PhosphoSitePlus	COSMIC	2.642	Down-regulation
CMGC_CDK_CDK4_CDK4_ST	Q08050	FOXM1	P11802	CDK4	S508	S505L	505	Missense	distal	-3	no	9.538	9.721	EPSD;PhosphoSitePlus	COSMIC	2.642	Up-regulation
CMGC_CDK_CDK4_CDK4_ST	Q08050	FOXM1	P11802	CDK4	S508	T510N	510	Missense	proximal	2	no	9.538	9.543	EPSD;PhosphoSitePlus	COSMIC;CCLE	2.642	Up-regulation
CMGC_CDK_CDK4_CDK4_ST	Q08050	FOXM1	P11802	CDK4	T510	S505L	505	Missense	distal	-5	no	8.407	8.255	PhosphoSitePlus;EPSD	COSMIC	2.642	Down-regulation
CMGC_CDK_CDK4_CDK4_ST	Q08050	FOXM1	P11802	CDK4	T510	T510N	510	Missense	central	0	yes	8.407	0.000	PhosphoSitePlus;EPSD	COSMIC;CCLE	2.642	Loss
CMGC_CDK_CDK4_CDK4_ST	Q08050	FOXM1	P11802	CDK4	S518	R521M	521	Missense	distal	3	no	2.834	2.418	EPSD	COSMIC	2.642	Loss
CMGC_CDK_CDK4_CDK4_ST	Q08050	FOXM1	P11802	CDK4	S518	T524S	524	Missense	distal	6	no	2.834	2.956	EPSD	COSMIC	2.642	Up-regulation
CMGC_CDK_CDK4_CDK4_ST	Q08050	FOXM1	P11802	CDK4	S518	S518I	518	Missense	central	0	yes	2.834	0.000	EPSD	COSMIC	2.642	Loss
CMGC_CDK_CDK4_CDK4_ST	Q08050	FOXM1	P11802	CDK4	S518	R525W	525	Missense	distal	7	no	2.834	2.824	EPSD	COSMIC	2.642	Down-regulation
CMGC_CDK_CDK4_CDK4_ST	Q08050	FOXM1	P11802	CDK4	S522	R521M	521	Missense	proximal	-1	no	8.895	9.036	EPSD;PhosphoSitePlus	COSMIC	2.642	Up-regulation
CMGC_CDK_CDK4_CDK4_ST	Q08050	FOXM1	P11802	CDK4	S522	T524S	524	Missense	proximal	2	no	8.895	9.083	EPSD;PhosphoSitePlus	COSMIC	2.642	Up-regulation
CMGC_CDK_CDK4_CDK4_ST	Q08050	FOXM1	P11802	CDK4	S522	S518I	518	Missense	distal	-4	no	8.895	8.896	EPSD;PhosphoSitePlus	COSMIC	2.642	Up-regulation
CMGC_CDK_CDK4_CDK4_ST	Q08050	FOXM1	P11802	CDK4	S522	V527A	527	Missense	distal	5	no	8.895	8.868	EPSD;PhosphoSitePlus	COSMIC	2.642	Down-regulation
CMGC_CDK_CDK4_CDK4_ST	Q08050	FOXM1	P11802	CDK4	S522	R525W	525	Missense	distal	3	no	8.895	8.405	EPSD;PhosphoSitePlus	COSMIC	2.642	Down-regulation
CMGC_CDK_CDK4_CDK4_ST	Q08050	FOXM1	P11802	CDK4	S522	C526S	526	Missense	distal	4	no	8.895	8.499	EPSD;PhosphoSitePlus	COSMIC	2.642	Down-regulation
CMGC_CDK_CDK4_CDK4_ST	Q08050	FOXM1	P11802	CDK4	S581	S582F	582	Missense	proximal	1	no	2.547	3.069	EPSD	COSMIC	2.642	Gain
CMGC_CDK_CDK4_CDK4_ST	Q08050	FOXM1	P11802	CDK4	T600	T605M	605	Missense	distal	5	no	6.555	6.566	EPSD;PhosphoSitePlus	COSMIC	2.642	Up-regulation
CMGC_CDK_CDK4_CDK4_ST	Q08050	FOXM1	P11802	CDK4	T611	S615Y	615	Missense	distal	4	no	7.242	7.551	EPSD;PhosphoSitePlus	COSMIC	2.642	Up-regulation
CMGC_CDK_CDK4_CDK4_ST	Q08050	FOXM1	P11802	CDK4	T611	S610T	610	Missense	proximal	-1	no	7.242	7.451	EPSD;PhosphoSitePlus	COSMIC	2.642	Up-regulation
CMGC_CDK_CDK4_CDK4_ST	Q08050	FOXM1	P11802	CDK4	T611	T605M	605	Missense	distal	-6	no	7.242	7.374	EPSD;PhosphoSitePlus	COSMIC	2.642	Up-regulation
CMGC_CDK_CDK4_CDK4_ST	Q08050	FOXM1	P11802	CDK4	T620	S615Y	615	Missense	distal	-5	no	8.588	8.468	EPSD;PhosphoSitePlus	COSMIC	2.642	Down-regulation
CMGC_CDK_CDK4_CDK4_ST	Q08050	FOXM1	P11802	CDK4	T620	P621L	621	Missense	proximal	1	no	8.588	1.009	EPSD;PhosphoSitePlus	COSMIC	2.642	Loss
CMGC_CDK_CDK4_CDK4_ST	Q08050	FOXM1	P11802	CDK4	T620	W624C	624	Missense	distal	4	no	8.588	8.581	EPSD;PhosphoSitePlus	COSMIC	2.642	Down-regulation
CMGC_CDK_CDK4_CDK4_ST	Q08050	FOXM1	P11802	CDK4	T627	P621L	621	Missense	distal	-6	no	7.652	7.805	EPSD;PhosphoSitePlus	COSMIC	2.642	Up-regulation
CMGC_CDK_CDK4_CDK4_ST	Q08050	FOXM1	P11802	CDK4	T627	V632G	632	Missense	distal	5	no	7.652	7.659	EPSD;PhosphoSitePlus	COSMIC	2.642	Up-regulation
CMGC_CDK_CDK4_CDK4_ST	Q08050	FOXM1	P11802	CDK4	T627	G633E	633	Missense	distal	6	no	7.652	7.819	EPSD;PhosphoSitePlus	COSMIC	2.642	Up-regulation
CMGC_CDK_CDK4_CDK4_ST	Q08050	FOXM1	P11802	CDK4	T627	W624C	624	Missense	distal	-3	no	7.652	7.653	EPSD;PhosphoSitePlus	COSMIC	2.642	Up-regulation
CMGC_CDK_CDK4_CDK4_ST	Q08050	FOXM1	P11802	CDK4	S638	D636H	636	Missense	proximal	-2	no	7.518	7.568	EPSD	COSMIC	2.642	Up-regulation
CMGC_CDK_CDK4_CDK4_ST	Q08050	FOXM1	P11802	CDK4	S638	S643P	643	Missense	distal	5	no	7.518	7.504	EPSD	COSMIC	2.642	Down-regulation
CMGC_CDK_CDK4_CDK4_ST	Q08050	FOXM1	P11802	CDK4	S638	V632G	632	Missense	distal	-6	no	7.518	7.709	EPSD	COSMIC	2.642	Up-regulation
CMGC_CDK_CDK4_CDK4_ST	Q08050	FOXM1	P11802	CDK4	S638	G633E	633	Missense	distal	-5	no	7.518	7.667	EPSD	COSMIC	2.642	Up-regulation
CMGC_CDK_CDK4_CDK4_ST	Q08050	FOXM1	P11802	CDK4	S660	P663H	663	Missense	distal	3	no	2.997	2.085	EPSD	COSMIC	2.642	Loss
CMGC_CDK_CDK4_CDK4_ST	Q08050	FOXM1	P11802	CDK4	S660	L659P	659	Missense	proximal	-1	no	2.997	2.960	EPSD	COSMIC	2.642	Down-regulation
CMGC_CDK_CDK4_CDK4_ST	Q08050	FOXM1	P11802	CDK4	S660	S666N	666	Missense	distal	6	no	2.997	2.858	EPSD	COSMIC	2.642	Down-regulation
CMGC_CDK_CDK4_CDK4_ST	Q08050	FOXM1	P11802	CDK4	T662	P663H	663	Missense	proximal	1	no	7.072	0.489	EPSD	COSMIC	2.642	Loss
CMGC_CDK_CDK4_CDK4_ST	Q08050	FOXM1	P11802	CDK4	T662	L659P	659	Missense	distal	-3	no	7.072	6.815	EPSD	COSMIC	2.642	Down-regulation
CMGC_CDK_CDK4_CDK4_ST	Q08050	FOXM1	P11802	CDK4	T662	S666N	666	Missense	distal	4	no	7.072	7.299	EPSD	COSMIC	2.642	Up-regulation
CMGC_CDK_CDK4_CDK4_ST	Q08050	FOXM1	P11802	CDK4	T662	P669L	669	Missense	distal	7	no	7.072	7.056	EPSD	COSMIC	2.642	Down-regulation
CMGC_CDK_CDK4_CDK4_ST	Q08050	FOXM1	P11802	CDK4	S666	L659P	659	Missense	distal	-7	no	2.302	2.782	EPSD	COSMIC	2.642	Gain
CMGC_CDK_CDK4_CDK4_ST	Q08050	FOXM1	P11802	CDK4	S672	P673S	673	Missense	proximal	1	no	7.934	1.747	EPSD	COSMIC	2.642	Loss
CMGC_CDK_CDK4_CDK4_ST	Q08050	FOXM1	P11802	CDK4	S672	R675K	675	Missense	distal	3	no	7.934	7.942	EPSD	COSMIC	2.642	Up-regulation
CMGC_CDK_CDK4_CDK4_ST	Q08050	FOXM1	P11802	CDK4	S672	S666N	666	Missense	distal	-6	no	7.934	8.146	EPSD	COSMIC	2.642	Up-regulation
CMGC_CDK_CDK4_CDK4_ST	Q08050	FOXM1	P11802	CDK4	S672	P669L	669	Missense	distal	-3	no	7.934	8.191	EPSD	COSMIC	2.642	Up-regulation
CMGC_CDK_CDK4_CDK4_ST	Q08050	FOXM1	P11802	CDK4	S672	L670P	670	Missense	proximal	-2	no	7.934	8.462	EPSD	COSMIC	2.642	Up-regulation
CMGC_CDK_CDK4_CDK4_ST	Q08050	FOXM1	P11802	CDK4	S678	P673S	673	Missense	distal	-5	no	3.018	3.154	EPSD	COSMIC	2.642	Up-regulation
CMGC_CDK_CDK4_CDK4_ST	Q08050	FOXM1	P11802	CDK4	S678	R675K	675	Missense	distal	-3	no	3.018	2.996	EPSD	COSMIC	2.642	Down-regulation
CMGC_CDK_CDK4_CDK4_ST	Q08050	FOXM1	P11802	CDK4	S693	S695L	695	Missense	proximal	2	no	9.227	8.999	EPSD	COSMIC	2.642	Down-regulation
CMGC_CDK_CDK4_CDK4_ST	Q08050	FOXM1	P11802	CDK4	S693	P688S	688	Missense	distal	-5	no	9.227	9.363	EPSD	COSMIC	2.642	Up-regulation
CMGC_CDK_CDK4_CDK4_ST	Q08050	FOXM1	P11802	CDK4	S693	S686F	686	Missense	distal	-7	no	9.227	8.514	EPSD	COSMIC	2.642	Down-regulation
CMGC_CDK_CDK4_CDK4_ST	Q08050	FOXM1	P11802	CDK4	S693	V687I	687	Missense	distal	-6	no	9.227	9.239	EPSD	COSMIC	2.642	Up-regulation
CMGC_CDK_CDK4_CDK4_ST	Q08050	FOXM1	P11802	CDK4	S704	V699I	699	Missense	distal	-5	no	9.031	9.036	EPSD;PhosphoSitePlus	COSMIC	2.642	Up-regulation
CMGC_CDK_CDK4_CDK4_ST	Q08050	FOXM1	P11802	CDK4	S704	P707L	707	Missense	distal	3	no	9.031	8.132	EPSD;PhosphoSitePlus	COSMIC;GDSC	2.642	Down-regulation
CMGC_CDK_CDK4_CDK4_ST	P30304	CDC25A	P11802	CDK4	S18	P21A	21	Missense	distal	3	no	8.502	7.868	EPSD	COSMIC	2.642	Down-regulation
CMGC_CDK_CDK4_CDK4_ST	P30304	CDC25A	P11802	CDK4	S40	G37W	37	Missense	distal	-3	no	9.282	9.232	PhosphoSitePlus	COSMIC	2.642	Down-regulation
CMGC_CDK_CDK4_CDK4_ST	P30304	CDC25A	P11802	CDK4	S76	N70H	70	Missense	distal	-6	no	3.342	3.444	EPSD	COSMIC	2.642	Up-regulation
CMGC_CDK_CDK4_CDK4_ST	P30304	CDC25A	P11802	CDK4	S76	S69G	69	Missense	distal	-7	no	3.342	2.429	EPSD	COSMIC	2.642	Loss
CMGC_CDK_CDK4_CDK4_ST	P30304	CDC25A	P11802	CDK4	S261	R255G	255	Missense	distal	-6	no	8.023	8.300	EPSD	COSMIC	2.642	Up-regulation
CMGC_CDK_CDK4_CDK4_ST	P30304	CDC25A	P11802	CDK4	S261	L264V	264	Missense	distal	3	no	8.023	7.865	EPSD	COSMIC	2.642	Down-regulation
CMGC_CDK_CDK4_CDK4_ST	P30304	CDC25A	P11802	CDK4	S298	S293N	293	Missense	distal	-5	no	7.647	7.554	EPSD	COSMIC	2.642	Down-regulation
CMGC_CDK_CDK4_CDK4_ST	P30304	CDC25A	P11802	CDK4	S321	P322L	322	Missense	proximal	1	no	6.140	-1.440	EPSD	COSMIC	2.642	Loss
CMGC_CDK_CDK4_CDK4_ST	P30304	CDC25A	P11802	CDK4	S321	S320Y	320	Missense	proximal	-1	no	6.140	6.386	EPSD	COSMIC	2.642	Up-regulation
CMGC_CDK_CDK4_CDK4_ST	P30304	CDC25A	P11802	CDK4	S361	V368A	368	Missense	distal	7	no	7.424	7.440	EPSD	COSMIC	2.642	Up-regulation
CMGC_CDK_CDK4_CDK4_ST	P30304	CDC25A	P11802	CDK4	S361	S367F	367	Missense	distal	6	no	7.424	7.200	EPSD	COSMIC	2.642	Down-regulation
CMGC_CDK_CDK4_CDK4_ST	P30304	CDC25A	P11802	CDK4	S361	S367P	367	Missense	distal	6	no	7.424	7.267	EPSD	COSMIC	2.642	Down-regulation
CMGC_CDK_CDK4_CDK4_ST	Q12778	FOXO1	P11802	CDK4	T231	S234R	234	Missense	distal	3	no	2.670	2.429	EPSD	COSMIC	2.642	Loss
CMGC_CDK_CDK4_CDK4_ST	Q12778	FOXO1	P11802	CDK4	T231	G232E	232	Missense	proximal	1	no	2.670	1.273	EPSD	COSMIC	2.642	Loss
CMGC_CDK_CDK4_CDK4_ST	Q12778	FOXO1	P11802	CDK4	S249	G243S	243	Missense	distal	-6	no	8.300	7.753	PhosphoSitePlus	COSMIC	2.642	Down-regulation
CMGC_CDK_CDK4_CDK4_ST	Q12778	FOXO1	P11802	CDK4	S249	G243V	243	Missense	distal	-6	no	8.300	8.108	PhosphoSitePlus	COSMIC	2.642	Down-regulation
CMGC_CDK_CDK4_CDK4_ST	Q12778	FOXO1	P11802	CDK4	S279	Q278L	278	Missense	proximal	-1	no	3.246	3.282	EPSD	COSMIC	2.642	Up-regulation
CMGC_CDK_CDK4_CDK4_ST	Q12778	FOXO1	P11802	CDK4	S279	L277F	277	Missense	proximal	-2	no	3.246	3.344	EPSD	COSMIC	2.642	Up-regulation
CMGC_CDK_CDK4_CDK4_ST	Q12778	FOXO1	P11802	CDK4	S287	S287N	287	Missense	central	0	yes	6.464	0.000	EPSD	COSMIC	2.642	Loss
CMGC_CDK_CDK4_CDK4_ST	Q12778	FOXO1	P11802	CDK4	S298	H302Y	302	Missense	distal	4	no	7.696	7.655	EPSD	COSMIC	2.642	Down-regulation
CMGC_CDK_CDK4_CDK4_ST	Q12778	FOXO1	P11802	CDK4	S301	H302Y	302	Missense	proximal	1	no	3.471	3.317	EPSD	COSMIC	2.642	Down-regulation
CMGC_CDK_CDK4_CDK4_ST	Q12778	FOXO1	P11802	CDK4	T312	N309D	309	Missense	distal	-3	no	2.680	2.756	EPSD	COSMIC;GDSC;CCLE	2.642	Up-regulation
CMGC_CDK_CDK4_CDK4_ST	Q12778	FOXO1	P11802	CDK4	T312	P315F	315	Missense	distal	3	no	2.680	1.784	EPSD	COSMIC	2.642	Loss
CMGC_CDK_CDK4_CDK4_ST	Q12778	FOXO1	P11802	CDK4	T312	W310C	310	Missense	proximal	-2	no	2.680	2.673	EPSD	COSMIC	2.642	Down-regulation
CMGC_CDK_CDK4_CDK4_ST	Q12778	FOXO1	P11802	CDK4	S318	P315F	315	Missense	distal	-3	no	3.323	3.545	EPSD	COSMIC	2.642	Up-regulation
CMGC_CDK_CDK4_CDK4_ST	Q12778	FOXO1	P11802	CDK4	S383	S382L	382	Missense	proximal	-1	no	7.429	7.714	EPSD	COSMIC;GDSC	2.642	Up-regulation
CMGC_CDK_CDK4_CDK4_ST	Q12778	FOXO1	P11802	CDK4	S383	L380I	380	Missense	distal	-3	no	7.429	7.433	EPSD	COSMIC	2.642	Up-regulation
CMGC_CDK_CDK4_CDK4_ST	Q12778	FOXO1	P11802	CDK4	S383	S390L	390	Missense	distal	7	no	7.429	7.404	EPSD	COSMIC	2.642	Down-regulation
CMGC_CDK_CDK4_CDK4_ST	Q12778	FOXO1	P11802	CDK4	S383	S386P	386	Missense	distal	3	no	7.429	7.734	EPSD	COSMIC	2.642	Up-regulation
CMGC_CDK_CDK4_CDK4_ST	Q12778	FOXO1	P11802	CDK4	S394	S393Y	393	Missense	proximal	-1	no	5.987	6.233	EPSD	COSMIC	2.642	Up-regulation
CMGC_CDK_CDK4_CDK4_ST	Q12778	FOXO1	P11802	CDK4	S394	S390L	390	Missense	distal	-4	no	5.987	5.988	EPSD	COSMIC	2.642	Up-regulation
CMGC_CDK_CDK4_CDK4_ST	Q12778	FOXO1	P11802	CDK4	T402	Y405C	405	Missense	distal	3	no	6.520	6.392	EPSD	COSMIC	2.642	Down-regulation
CMGC_CDK_CDK4_CDK4_ST	Q12778	FOXO1	P11802	CDK4	S416	P417S	417	Missense	proximal	1	no	7.267	1.080	EPSD	COSMIC	2.642	Loss
CMGC_CDK_CDK4_CDK4_ST	Q12778	FOXO1	P11802	CDK4	S418	P417S	417	Missense	proximal	-1	no	8.469	8.221	EPSD	COSMIC	2.642	Down-regulation
CMGC_CDK_CDK4_CDK4_ST	Q12778	FOXO1	P11802	CDK4	S432	P438H	438	Missense	distal	6	no	8.212	8.184	EPSD	COSMIC	2.642	Down-regulation
CMGC_CDK_CDK4_CDK4_ST	Q12778	FOXO1	P11802	CDK4	S432	S432N	432	Missense	central	0	yes	8.212	0.000	EPSD	COSMIC	2.642	Loss
CMGC_CDK_CDK4_CDK4_ST	Q12778	FOXO1	P11802	CDK4	S432	I439V	439	Missense	distal	7	no	8.212	8.213	EPSD	COSMIC	2.642	Up-regulation
CMGC_CDK_CDK4_CDK4_ST	Q12778	FOXO1	P11802	CDK4	S432	G427V	427	Missense	distal	-5	no	8.212	8.297	EPSD	COSMIC	2.642	Up-regulation
CMGC_CDK_CDK4_CDK4_ST	Q12778	FOXO1	P11802	CDK4	S468	D469A	469	Missense	proximal	1	no	3.023	3.273	EPSD	COSMIC	2.642	Up-regulation
CMGC_CDK_CDK4_CDK4_ST	Q12778	FOXO1	P11802	CDK4	S468	K463N	463	Missense	distal	-5	no	3.023	3.021	EPSD	COSMIC	2.642	Down-regulation
CMGC_CDK_CDK4_CDK4_ST	Q12778	FOXO1	P11802	CDK4	S468	L462F	462	Missense	distal	-6	no	3.023	3.029	EPSD	COSMIC	2.642	Up-regulation
CMGC_CDK_CDK4_CDK4_ST	Q12778	FOXO1	P11802	CDK4	S468	N474D	474	Missense	distal	6	no	3.023	2.969	EPSD	COSMIC	2.642	Down-regulation
CMGC_CDK_CDK4_CDK4_ST	Q12778	FOXO1	P11802	CDK4	S470	D469A	469	Missense	proximal	-1	no	8.382	8.136	EPSD	COSMIC	2.642	Down-regulation
CMGC_CDK_CDK4_CDK4_ST	Q12778	FOXO1	P11802	CDK4	S470	K463N	463	Missense	distal	-7	no	8.382	8.343	EPSD	COSMIC	2.642	Down-regulation
CMGC_CDK_CDK4_CDK4_ST	Q12778	FOXO1	P11802	CDK4	S470	N474D	474	Missense	distal	4	no	8.382	8.548	EPSD	COSMIC	2.642	Up-regulation
CMGC_CDK_CDK4_CDK4_ST	Q12778	FOXO1	P11802	CDK4	T478	P482A	482	Missense	distal	4	no	6.760	6.646	EPSD	COSMIC	2.642	Down-regulation
CMGC_CDK_CDK4_CDK4_ST	Q12778	FOXO1	P11802	CDK4	T478	P482H	482	Missense	distal	4	no	6.760	6.903	EPSD	COSMIC	2.642	Up-regulation
CMGC_CDK_CDK4_CDK4_ST	Q12778	FOXO1	P11802	CDK4	T478	P479S	479	Missense	proximal	1	no	6.760	0.573	EPSD	COSMIC	2.642	Loss
CMGC_CDK_CDK4_CDK4_ST	Q12778	FOXO1	P11802	CDK4	T478	N474D	474	Missense	distal	-4	no	6.760	6.761	EPSD	COSMIC	2.642	Up-regulation
CMGC_CDK_CDK4_CDK4_ST	P84022	SMAD3	P11802	CDK4	T8	P9L	9	Missense	proximal	1	no	7.461	-0.118	EPSD;PhosphoSitePlus	COSMIC	2.642	Loss
CMGC_CDK_CDK4_CDK4_ST	P84022	SMAD3	P11802	CDK4	T132	H126R	126	Missense	distal	-6	no	5.784	5.740	EPSD	COSMIC	2.642	Down-regulation
CMGC_CDK_CDK4_CDK4_ST	P84022	SMAD3	P11802	CDK4	T132	P137L	137	Missense	distal	5	no	5.784	5.835	EPSD	COSMIC	2.642	Up-regulation
CMGC_CDK_CDK4_CDK4_ST	P84022	SMAD3	P11802	CDK4	T132	V134A	134	Missense	proximal	2	no	5.784	5.962	EPSD	COSMIC	2.642	Up-regulation
CMGC_CDK_CDK4_CDK4_ST	P84022	SMAD3	P11802	CDK4	T132	V138L	138	Missense	distal	6	no	5.784	5.803	EPSD	COSMIC	2.642	Up-regulation
CMGC_CDK_CDK4_CDK4_ST	P84022	SMAD3	P11802	CDK4	T132	P136R	136	Missense	distal	4	no	5.784	5.809	EPSD	COSMIC	2.642	Up-regulation
CMGC_CDK_CDK4_CDK4_ST	P84022	SMAD3	P11802	CDK4	T132	P133L	133	Missense	proximal	1	no	5.784	-1.795	EPSD	COSMIC	2.642	Loss
CMGC_CDK_CDK4_CDK4_ST	P84022	SMAD3	P11802	CDK4	T179	P182S	182	Missense	distal	3	no	8.331	8.026	EPSD;PhosphoSitePlus	COSMIC	2.642	Down-regulation
CMGC_CDK_CDK4_CDK4_ST	P84022	SMAD3	P11802	CDK4	T179	P177L	177	Missense	proximal	-2	no	8.331	7.802	EPSD;PhosphoSitePlus	COSMIC	2.642	Down-regulation
CMGC_CDK_CDK4_CDK4_ST	P84022	SMAD3	P11802	CDK4	T179	P172H	172	Missense	distal	-7	no	8.331	7.896	EPSD;PhosphoSitePlus	COSMIC	2.642	Down-regulation
CMGC_CDK_CDK4_CDK4_ST	P84022	SMAD3	P11802	CDK4	S204	S204N	204	Missense	central	0	yes	7.126	0.000	EPSD;PhosphoSitePlus	COSMIC	2.642	Loss
CMGC_CDK_CDK4_CDK4_ST	P84022	SMAD3	P11802	CDK4	S204	P211S	211	Missense	distal	7	no	7.126	7.134	EPSD;PhosphoSitePlus	COSMIC	2.642	Up-regulation
CMGC_CDK_CDK4_CDK4_ST	P84022	SMAD3	P11802	CDK4	S204	A202T	202	Missense	proximal	-2	no	7.126	7.104	EPSD;PhosphoSitePlus	COSMIC	2.642	Down-regulation
CMGC_CDK_CDK4_CDK4_ST	P84022	SMAD3	P11802	CDK4	S204	S204F	204	Missense	central	0	yes	7.126	0.000	EPSD;PhosphoSitePlus	COSMIC	2.642	Loss
CMGC_CDK_CDK4_CDK4_ST	P84022	SMAD3	P11802	CDK4	S204	P211L	211	Missense	distal	7	no	7.126	7.110	EPSD;PhosphoSitePlus	COSMIC	2.642	Down-regulation
CMGC_CDK_CDK4_CDK4_ST	P84022	SMAD3	P11802	CDK4	S204	P209S	209	Missense	distal	5	no	7.126	7.140	EPSD;PhosphoSitePlus	COSMIC	2.642	Up-regulation
CMGC_CDK_CDK4_CDK4_ST	P84022	SMAD3	P11802	CDK4	S204	N197K	197	Missense	distal	-7	no	7.126	7.165	EPSD;PhosphoSitePlus	COSMIC	2.642	Up-regulation
CMGC_CDK_CDK4_CDK4_ST	P84022	SMAD3	P11802	CDK4	S208	S204N	204	Missense	distal	-4	no	7.256	7.257	PhosphoSitePlus;EPSD	COSMIC	2.642	Up-regulation
CMGC_CDK_CDK4_CDK4_ST	P84022	SMAD3	P11802	CDK4	S208	P211S	211	Missense	distal	3	no	7.256	6.951	PhosphoSitePlus;EPSD	COSMIC	2.642	Down-regulation
CMGC_CDK_CDK4_CDK4_ST	P84022	SMAD3	P11802	CDK4	S208	A202T	202	Missense	distal	-6	no	7.256	7.343	PhosphoSitePlus;EPSD	COSMIC	2.642	Up-regulation
CMGC_CDK_CDK4_CDK4_ST	P84022	SMAD3	P11802	CDK4	S208	S204F	204	Missense	distal	-4	no	7.256	7.257	PhosphoSitePlus;EPSD	COSMIC	2.642	Up-regulation
CMGC_CDK_CDK4_CDK4_ST	P84022	SMAD3	P11802	CDK4	S208	P211L	211	Missense	distal	3	no	7.256	6.357	PhosphoSitePlus;EPSD	COSMIC	2.642	Down-regulation
CMGC_CDK_CDK4_CDK4_ST	P84022	SMAD3	P11802	CDK4	S208	P209S	209	Missense	proximal	1	no	7.256	1.069	PhosphoSitePlus;EPSD	COSMIC	2.642	Loss
CMGC_CDK_CDK4_CDK4_ST	P84022	SMAD3	P11802	CDK4	S213	P211S	211	Missense	proximal	-2	no	7.568	7.263	EPSD;PhosphoSitePlus	COSMIC	2.642	Down-regulation
CMGC_CDK_CDK4_CDK4_ST	P84022	SMAD3	P11802	CDK4	S213	P211L	211	Missense	proximal	-2	no	7.568	7.039	EPSD;PhosphoSitePlus	COSMIC	2.642	Down-regulation
CMGC_CDK_CDK4_CDK4_ST	P84022	SMAD3	P11802	CDK4	T286	R287P	287	Missense	proximal	1	no	0.015	6.802	EPSD	COSMIC	2.642	Gain
CMGC_CDK_CDK4_CDK4_ST	P84022	SMAD3	P11802	CDK4	S375	G381E	381	Missense	distal	6	no	2.561	2.728	EPSD	COSMIC	2.642	Gain
CMGC_CDK_CDK4_CDK4_ST	P84022	SMAD3	P11802	CDK4	S416	S423G	423	Missense	distal	7	no	8.706	8.672	EPSD	COSMIC	2.642	Down-regulation
CMGC_CDK_CDK4_CDK4_ST	P84022	SMAD3	P11802	CDK4	S416	S423I	423	Missense	distal	7	no	8.706	8.680	EPSD	COSMIC	2.642	Down-regulation
CMGC_CDK_CDK4_CDK4_ST	P84022	SMAD3	P11802	CDK4	S416	V410I	410	Missense	distal	-6	no	8.706	8.718	EPSD	COSMIC	2.642	Up-regulation
CMGC_CDK_CDK4_CDK4_ST	P84022	SMAD3	P11802	CDK4	S416	S422Y	422	Missense	distal	6	no	8.706	8.537	EPSD	COSMIC	2.642	Down-regulation
CMGC_CDK_CDK4_CDK4_ST	P84022	SMAD3	P11802	CDK4	S416	C421Y	421	Missense	distal	5	no	8.706	8.698	EPSD	COSMIC	2.642	Down-regulation
CMGC_CDK_CDK4_CDK4_ST	P84022	SMAD3	P11802	CDK4	S416	R420C	420	Missense	distal	4	no	8.706	8.870	EPSD	COSMIC	2.642	Up-regulation
CMGC_CDK_CDK4_CDK4_ST	P26358	DNMT1	P11802	CDK4	S91	L92F	92	Missense	proximal	1	no	1.307	3.222	EPSD	COSMIC	2.642	Gain
CMGC_CDK_CDK4_CDK4_ST	P26358	DNMT1	P11802	CDK4	S127	P128T	128	Missense	proximal	1	no	7.446	0.920	PhosphoSitePlus;EPSD	COSMIC;GDSC	2.642	Loss
CMGC_CDK_CDK4_CDK4_ST	P26358	DNMT1	P11802	CDK4	S127	S133F	133	Missense	distal	6	no	7.446	7.222	PhosphoSitePlus;EPSD	COSMIC	2.642	Down-regulation
CMGC_CDK_CDK4_CDK4_ST	P26358	DNMT1	P11802	CDK4	S127	P129L	129	Missense	proximal	2	no	7.446	7.378	PhosphoSitePlus;EPSD	COSMIC	2.642	Down-regulation
CMGC_CDK_CDK4_CDK4_ST	P26358	DNMT1	P11802	CDK4	S127	L132P	132	Missense	distal	5	no	7.446	7.396	PhosphoSitePlus;EPSD	COSMIC	2.642	Down-regulation
CMGC_CDK_CDK4_CDK4_ST	P26358	DNMT1	P11802	CDK4	S127	D124C	124	Missense	distal	-3	no	7.446	7.443	PhosphoSitePlus;EPSD	COSMIC	2.642	Down-regulation
CMGC_CDK_CDK4_CDK4_ST	P26358	DNMT1	P11802	CDK4	T137	S133F	133	Missense	distal	-4	no	7.575	7.576	EPSD	COSMIC	2.642	Up-regulation
CMGC_CDK_CDK4_CDK4_ST	P26358	DNMT1	P11802	CDK4	T137	R140K	140	Missense	distal	3	no	7.575	7.583	EPSD	COSMIC	2.642	Up-regulation
CMGC_CDK_CDK4_CDK4_ST	P26358	DNMT1	P11802	CDK4	T137	R136C	136	Missense	proximal	-1	no	7.575	7.769	EPSD	COSMIC	2.642	Up-regulation
CMGC_CDK_CDK4_CDK4_ST	P26358	DNMT1	P11802	CDK4	T137	L132P	132	Missense	distal	-5	no	7.575	7.590	EPSD	COSMIC	2.642	Up-regulation
CMGC_CDK_CDK4_CDK4_ST	P26358	DNMT1	P11802	CDK4	T137	D144N	144	Missense	distal	7	no	7.575	7.584	EPSD	COSMIC	2.642	Up-regulation
CMGC_CDK_CDK4_CDK4_ST	P26358	DNMT1	P11802	CDK4	S152	S154C	154	Missense	proximal	2	no	8.760	8.463	EPSD	COSMIC	2.642	Down-regulation
CMGC_CDK_CDK4_CDK4_ST	P26358	DNMT1	P11802	CDK4	S154	S161G	161	Missense	distal	7	no	7.264	7.230	EPSD	COSMIC	2.642	Down-regulation
CMGC_CDK_CDK4_CDK4_ST	P26358	DNMT1	P11802	CDK4	S154	S154C	154	Missense	central	0	yes	7.264	0.000	EPSD	COSMIC	2.642	Loss
CMGC_CDK_CDK4_CDK4_ST	P26358	DNMT1	P11802	CDK4	T166	I167F	167	Missense	proximal	1	no	1.027	2.886	EPSD	COSMIC	2.642	Gain
CMGC_CDK_CDK4_CDK4_ST	P26358	DNMT1	P11802	CDK4	T253	P252L	252	Missense	proximal	-1	no	6.136	6.173	EPSD	COSMIC	2.642	Up-regulation
CMGC_CDK_CDK4_CDK4_ST	P26358	DNMT1	P11802	CDK4	T253	R246Q	246	Missense	distal	-7	no	6.136	6.077	EPSD	COSMIC	2.642	Down-regulation
CMGC_CDK_CDK4_CDK4_ST	P26358	DNMT1	P11802	CDK4	T253	P254H	254	Missense	proximal	1	no	6.136	-0.447	EPSD	COSMIC	2.642	Loss
CMGC_CDK_CDK4_CDK4_ST	P26358	DNMT1	P11802	CDK4	T253	R246C	246	Missense	distal	-7	no	6.136	5.872	EPSD	COSMIC	2.642	Down-regulation
CMGC_CDK_CDK4_CDK4_ST	P26358	DNMT1	P11802	CDK4	T253	R246H	246	Missense	distal	-7	no	6.136	5.988	EPSD	COSMIC	2.642	Down-regulation
CMGC_CDK_CDK4_CDK4_ST	P26358	DNMT1	P11802	CDK4	T328	R325H	325	Missense	distal	-3	no	6.601	6.644	EPSD	COSMIC	2.642	Up-regulation
CMGC_CDK_CDK4_CDK4_ST	P26358	DNMT1	P11802	CDK4	T328	R325L	325	Missense	distal	-3	no	6.601	6.679	EPSD	COSMIC	2.642	Up-regulation
CMGC_CDK_CDK4_CDK4_ST	P26358	DNMT1	P11802	CDK4	T328	P332L	332	Missense	distal	4	no	6.601	6.761	EPSD	COSMIC	2.642	Up-regulation
CMGC_CDK_CDK4_CDK4_ST	P26358	DNMT1	P11802	CDK4	T328	E321G	321	Missense	distal	-7	no	6.601	6.072	EPSD	COSMIC	2.642	Down-regulation
CMGC_CDK_CDK4_CDK4_ST	P26358	DNMT1	P11802	CDK4	S714	M712T	712	Missense	proximal	-2	no	7.377	7.432	EPSD	COSMIC;GDSC	2.642	Up-regulation
CMGC_CDK_CDK4_CDK4_ST	P26358	DNMT1	P11802	CDK4	S714	M712L	712	Missense	proximal	-2	no	7.377	7.325	EPSD	COSMIC	2.642	Down-regulation
CMGC_CDK_CDK4_CDK4_ST	P26358	DNMT1	P11802	CDK4	S878	P879S	879	Missense	proximal	1	no	7.979	1.792	EPSD	COSMIC;CCLE	2.642	Loss
CMGC_CDK_CDK4_CDK4_ST	P26358	DNMT1	P11802	CDK4	S878	E877K	877	Missense	proximal	-1	no	7.979	7.888	EPSD	COSMIC	2.642	Down-regulation
CMGC_CDK_CDK4_CDK4_ST	P26358	DNMT1	P11802	CDK4	S878	T882I	882	Missense	distal	4	no	7.979	8.142	EPSD	COSMIC	2.642	Up-regulation
CMGC_CDK_CDK4_CDK4_ST	P26358	DNMT1	P11802	CDK4	S954	R958C	958	Missense	distal	4	no	8.383	8.547	EPSD;PhosphoSitePlus	COSMIC	2.642	Up-regulation
CMGC_CDK_CDK4_CDK4_ST	P26358	DNMT1	P11802	CDK4	S954	P955L	955	Missense	proximal	1	no	8.383	0.803	EPSD;PhosphoSitePlus	COSMIC	2.642	Loss
CMGC_CDK_CDK4_CDK4_ST	P26358	DNMT1	P11802	CDK4	S954	K961N	961	Missense	distal	7	no	8.383	8.380	EPSD;PhosphoSitePlus	COSMIC	2.642	Down-regulation
CMGC_CDK_CDK4_CDK4_ST	P26358	DNMT1	P11802	CDK4	S954	R960Q	960	Missense	distal	6	no	8.383	8.335	EPSD;PhosphoSitePlus	COSMIC	2.642	Down-regulation
CMGC_CDK_CDK4_CDK4_ST	P26358	DNMT1	P11802	CDK4	S954	K951R	951	Missense	distal	-3	no	8.383	8.404	EPSD;PhosphoSitePlus	COSMIC	2.642	Up-regulation
CMGC_CDK_CDK4_CDK4_ST	P26358	DNMT1	P11802	CDK4	S954	R958H	958	Missense	distal	4	no	8.383	8.502	EPSD;PhosphoSitePlus	COSMIC	2.642	Up-regulation
CMGC_CDK_CDK4_CDK4_ST	P26358	DNMT1	P11802	CDK4	S954	P959S	959	Missense	distal	5	no	8.383	8.396	EPSD;PhosphoSitePlus	COSMIC	2.642	Up-regulation
CMGC_CDK_CDK4_CDK4_ST	P26358	DNMT1	P11802	CDK4	S954	T947M	947	Missense	distal	-7	no	8.383	8.168	EPSD;PhosphoSitePlus	COSMIC	2.642	Down-regulation
CMGC_CDK_CDK4_CDK4_ST	P26358	DNMT1	P11802	CDK4	S954	I950M	950	Missense	distal	-4	no	8.383	8.382	EPSD;PhosphoSitePlus	COSMIC	2.642	Down-regulation
CMGC_CDK_CDK4_CDK4_ST	P26358	DNMT1	P11802	CDK4	S1105	D1098V	1098	Missense	distal	-7	no	7.262	7.175	EPSD	COSMIC	2.642	Down-regulation
CMGC_CDK_CDK4_CDK4_ST	P26358	DNMT1	P11802	CDK4	S1105	R1104C	1104	Missense	proximal	-1	no	7.262	7.457	EPSD	COSMIC	2.642	Up-regulation
CMGC_CDK_CDK4_CDK4_ST	P26358	DNMT1	P11802	CDK4	S1105	P1106L	1106	Missense	proximal	1	no	7.262	-0.317	EPSD	COSMIC	2.642	Loss
CMGC_CDK_CDK4_CDK4_ST	P26358	DNMT1	P11802	CDK4	S1122	Q1123P	1123	Missense	proximal	1	no	1.765	8.934	EPSD	COSMIC	2.642	Gain
CMGC_CDK_CDK4_CDK4_ST	P26358	DNMT1	P11802	CDK4	S1358	S1352G	1352	Missense	distal	-6	no	2.199	2.746	EPSD	COSMIC	2.642	Gain
CMGC_CDK_CDK4_CDK4_ST	Q14814	MEF2D	P11802	CDK4	S98	D102N	102	Missense	distal	4	no	8.576	8.410	PhosphoSitePlus;EPSD	COSMIC	2.642	Down-regulation
CMGC_CDK_CDK4_CDK4_ST	Q14814	MEF2D	P11802	CDK4	S98	E100G	100	Missense	proximal	2	no	8.576	8.332	PhosphoSitePlus;EPSD	COSMIC	2.642	Down-regulation
CMGC_CDK_CDK4_CDK4_ST	Q14814	MEF2D	P11802	CDK4	S98	G103R	103	Missense	distal	5	no	8.576	8.551	PhosphoSitePlus;EPSD	COSMIC	2.642	Down-regulation
CMGC_CDK_CDK4_CDK4_ST	Q14814	MEF2D	P11802	CDK4	S98	P101H	101	Missense	distal	3	no	8.576	7.663	PhosphoSitePlus;EPSD	COSMIC	2.642	Down-regulation
CMGC_CDK_CDK4_CDK4_ST	Q14814	MEF2D	P11802	CDK4	S98	D97Y	97	Missense	proximal	-1	no	8.576	8.499	PhosphoSitePlus;EPSD	COSMIC	2.642	Down-regulation
CMGC_CDK_CDK4_CDK4_ST	Q14814	MEF2D	P11802	CDK4	S110	G103R	103	Missense	distal	-7	no	7.937	8.363	EPSD;PhosphoSitePlus	COSMIC	2.642	Up-regulation
CMGC_CDK_CDK4_CDK4_ST	Q14814	MEF2D	P11802	CDK4	S180	R177W	177	Missense	distal	-3	no	7.159	7.228	EPSD	COSMIC	2.642	Up-regulation
CMGC_CDK_CDK4_CDK4_ST	Q14814	MEF2D	P11802	CDK4	S180	L178M	178	Missense	proximal	-2	no	7.159	7.211	EPSD	COSMIC	2.642	Up-regulation
CMGC_CDK_CDK4_CDK4_ST	Q14814	MEF2D	P11802	CDK4	S231	L235F	235	Missense	distal	4	no	7.055	7.085	EPSD	COSMIC	2.642	Up-regulation
CMGC_CDK_CDK4_CDK4_ST	Q14814	MEF2D	P11802	CDK4	S231	P236H	236	Missense	distal	5	no	7.055	7.101	EPSD	COSMIC	2.642	Up-regulation
CMGC_CDK_CDK4_CDK4_ST	Q14814	MEF2D	P11802	CDK4	S231	L234F	234	Missense	distal	3	no	7.055	7.058	EPSD	COSMIC	2.642	Up-regulation
CMGC_CDK_CDK4_CDK4_ST	Q14814	MEF2D	P11802	CDK4	S251	S258R	258	Missense	distal	7	no	8.081	8.067	EPSD	COSMIC	2.642	Down-regulation
CMGC_CDK_CDK4_CDK4_ST	Q14814	MEF2D	P11802	CDK4	S251	P254S	254	Missense	distal	3	no	8.081	7.777	EPSD	COSMIC	2.642	Down-regulation
CMGC_CDK_CDK4_CDK4_ST	Q14814	MEF2D	P11802	CDK4	T286	E287K	287	Missense	proximal	1	no	2.110	2.681	EPSD	COSMIC	2.642	Gain
CMGC_CDK_CDK4_CDK4_ST	Q14814	MEF2D	P11802	CDK4	T286	E287G	287	Missense	proximal	1	no	2.110	3.508	EPSD	COSMIC	2.642	Gain
CMGC_CDK_CDK4_CDK4_ST	Q14814	MEF2D	P11802	CDK4	S444	P442L	442	Missense	proximal	-2	no	10.359	9.830	EPSD	COSMIC	2.642	Down-regulation
CMGC_CDK_CDK4_CDK4_ST	Q14814	MEF2D	P11802	CDK4	S444	R449C	449	Missense	distal	5	no	10.359	10.376	EPSD	COSMIC	2.642	Up-regulation
CMGC_CDK_CDK4_CDK4_ST	Q14814	MEF2D	P11802	CDK4	S444	R447H	447	Missense	distal	3	no	10.359	9.992	EPSD	COSMIC	2.642	Down-regulation
CMGC_CDK_CDK4_CDK4_ST	Q14814	MEF2D	P11802	CDK4	S450	P453S	453	Missense	distal	3	no	7.572	7.267	EPSD	COSMIC	2.642	Down-regulation
CMGC_CDK_CDK4_CDK4_ST	Q14814	MEF2D	P11802	CDK4	S450	R449C	449	Missense	proximal	-1	no	7.572	7.767	EPSD	COSMIC	2.642	Up-regulation
CMGC_CDK_CDK4_CDK4_ST	Q14814	MEF2D	P11802	CDK4	S450	R447H	447	Missense	distal	-3	no	7.572	7.615	EPSD	COSMIC	2.642	Up-regulation
CMGC_CDK_CDK4_CDK4_ST	Q14814	MEF2D	P11802	CDK4	S472	G469E	469	Missense	distal	-3	no	8.018	7.908	EPSD	COSMIC	2.642	Down-regulation
CMGC_CDK_CDK4_CDK4_ST	Q14814	MEF2D	P11802	CDK4	S472	P466L	466	Missense	distal	-6	no	8.018	8.171	EPSD	COSMIC	2.642	Up-regulation
CMGC_CDK_CDK4_CDK4_ST	Q14814	MEF2D	P11802	CDK4	S472	P466A	466	Missense	distal	-6	no	8.018	7.909	EPSD	COSMIC	2.642	Down-regulation
CMGC_CDK_CDK4_CDK4_ST	Q14814	MEF2D	P11802	CDK4	S472	P473A	473	Missense	proximal	1	no	8.018	1.080	EPSD	COSMIC	2.642	Loss
CMGC_CDK_CDK4_CDK4_ST	Q14814	MEF2D	P11802	CDK4	S472	P466S	466	Missense	distal	-6	no	8.018	7.808	EPSD	COSMIC	2.642	Down-regulation
CMGC_CDK_CDK4_CDK4_ST	Q14814	MEF2D	P11802	CDK4	S472	S477A	477	Missense	distal	5	no	8.018	8.033	EPSD	COSMIC	2.642	Up-regulation
CMGC_CDK_CDK4_CDK4_ST	Q14814	MEF2D	P11802	CDK4	S472	G469C	469	Missense	distal	-3	no	8.018	7.969	EPSD	COSMIC;GDSC;CCLE	2.642	Down-regulation
CMGC_CDK_CDK4_CDK4_ST	P38398	BRCA1	P11802	CDK4	S114	D120A	120	Missense	distal	6	no	6.552	6.668	EPSD	COSMIC	2.642	Up-regulation
CMGC_CDK_CDK4_CDK4_ST	P38398	BRCA1	P11802	CDK4	S114	P115L	115	Missense	proximal	1	no	6.552	-1.027	EPSD	COSMIC	2.642	Loss
CMGC_CDK_CDK4_CDK4_ST	P38398	BRCA1	P11802	CDK4	S114	F107Y	107	Missense	distal	-7	no	6.552	6.669	EPSD	COSMIC	2.642	Up-regulation
CMGC_CDK_CDK4_CDK4_ST	P38398	BRCA1	P11802	CDK4	S114	N113S	113	Missense	proximal	-1	no	6.552	6.352	EPSD	COSMIC	2.642	Down-regulation
CMGC_CDK_CDK4_CDK4_ST	P38398	BRCA1	P11802	CDK4	S114	E111K	111	Missense	distal	-3	no	6.552	6.522	EPSD	COSMIC	2.642	Down-regulation
CMGC_CDK_CDK4_CDK4_ST	P38398	BRCA1	P11802	CDK4	S114	A108V	108	Missense	distal	-6	no	6.552	6.807	EPSD	COSMIC	2.642	Up-regulation
CMGC_CDK_CDK4_CDK4_ST	P38398	BRCA1	P11802	CDK4	S114	E116K	116	Missense	proximal	2	no	6.552	6.637	EPSD	COSMIC	2.642	Up-regulation
CMGC_CDK_CDK4_CDK4_ST	P38398	BRCA1	P11802	CDK4	S114	P115R	115	Missense	proximal	1	no	6.552	-0.235	EPSD	COSMIC	2.642	Loss
CMGC_CDK_CDK4_CDK4_ST	P38398	BRCA1	P11802	CDK4	S186	N192S	192	Missense	distal	6	no	2.631	2.771	EPSD	COSMIC	2.642	Gain
CMGC_CDK_CDK4_CDK4_ST	P38398	BRCA1	P11802	CDK4	T208	E215K	215	Missense	distal	7	no	5.791	5.793	EPSD	COSMIC	2.642	Up-regulation
CMGC_CDK_CDK4_CDK4_ST	P38398	BRCA1	P11802	CDK4	T208	Q202R	202	Missense	distal	-6	no	5.791	5.786	EPSD	COSMIC	2.642	Down-regulation
CMGC_CDK_CDK4_CDK4_ST	P38398	BRCA1	P11802	CDK4	T208	Q210E	210	Missense	proximal	2	no	5.791	5.831	EPSD	COSMIC	2.642	Up-regulation
CMGC_CDK_CDK4_CDK4_ST	P38398	BRCA1	P11802	CDK4	T208	E203K	203	Missense	distal	-5	no	5.791	5.778	EPSD	COSMIC	2.642	Down-regulation
CMGC_CDK_CDK4_CDK4_ST	P38398	BRCA1	P11802	CDK4	T333	C328Y	328	Missense	distal	-5	no	7.129	7.166	EPSD	COSMIC;GDSC;CCLE	2.642	Up-regulation
CMGC_CDK_CDK4_CDK4_ST	P38398	BRCA1	P11802	CDK4	T333	K338I	338	Missense	distal	5	no	7.129	7.150	EPSD	COSMIC	2.642	Up-regulation
CMGC_CDK_CDK4_CDK4_ST	P38398	BRCA1	P11802	CDK4	T333	P334S	334	Missense	proximal	1	no	7.129	0.942	EPSD	COSMIC	2.642	Loss
CMGC_CDK_CDK4_CDK4_ST	P38398	BRCA1	P11802	CDK4	T333	S335N	335	Missense	proximal	2	no	7.129	6.945	EPSD	COSMIC	2.642	Down-regulation
CMGC_CDK_CDK4_CDK4_ST	P38398	BRCA1	P11802	CDK4	T333	R332Q	332	Missense	proximal	-1	no	7.129	7.233	EPSD	COSMIC	2.642	Up-regulation
CMGC_CDK_CDK4_CDK4_ST	P38398	BRCA1	P11802	CDK4	T333	D330N	330	Missense	distal	-3	no	7.129	7.052	EPSD	COSMIC	2.642	Down-regulation
CMGC_CDK_CDK4_CDK4_ST	P38398	BRCA1	P11802	CDK4	T333	R332W	332	Missense	proximal	-1	no	7.129	7.322	EPSD	COSMIC	2.642	Up-regulation
CMGC_CDK_CDK4_CDK4_ST	P38398	BRCA1	P11802	CDK4	T333	R331G	331	Missense	proximal	-2	no	7.129	7.053	EPSD	COSMIC	2.642	Down-regulation
CMGC_CDK_CDK4_CDK4_ST	P38398	BRCA1	P11802	CDK4	T333	S335I	335	Missense	proximal	2	no	7.129	6.853	EPSD	COSMIC	2.642	Down-regulation
CMGC_CDK_CDK4_CDK4_ST	P38398	BRCA1	P11802	CDK4	T333	E337V	337	Missense	distal	4	no	7.129	7.292	EPSD	COSMIC	2.642	Up-regulation
CMGC_CDK_CDK4_CDK4_ST	P38398	BRCA1	P11802	CDK4	T333	T327A	327	Missense	distal	-6	no	7.129	7.041	EPSD	COSMIC	2.642	Down-regulation
CMGC_CDK_CDK4_CDK4_ST	P38398	BRCA1	P11802	CDK4	S423	D430N	430	Missense	distal	7	no	3.261	3.271	EPSD	COSMIC	2.642	Up-regulation
CMGC_CDK_CDK4_CDK4_ST	P38398	BRCA1	P11802	CDK4	S423	S426L	426	Missense	distal	3	no	3.261	2.667	EPSD	COSMIC	2.642	Down-regulation
CMGC_CDK_CDK4_CDK4_ST	P38398	BRCA1	P11802	CDK4	S423	V419E	419	Missense	distal	-4	no	3.261	3.260	EPSD	COSMIC	2.642	Down-regulation
CMGC_CDK_CDK4_CDK4_ST	P38398	BRCA1	P11802	CDK4	S423	L416I	416	Missense	distal	-7	no	3.261	3.297	EPSD	COSMIC	2.642	Up-regulation
CMGC_CDK_CDK4_CDK4_ST	P38398	BRCA1	P11802	CDK4	S425	D430N	430	Missense	distal	5	no	3.107	3.093	EPSD	COSMIC	2.642	Down-regulation
CMGC_CDK_CDK4_CDK4_ST	P38398	BRCA1	P11802	CDK4	S425	S426L	426	Missense	proximal	1	no	3.107	1.715	EPSD	COSMIC	2.642	Loss
CMGC_CDK_CDK4_CDK4_ST	P38398	BRCA1	P11802	CDK4	S425	V419E	419	Missense	distal	-6	no	3.107	2.961	EPSD	COSMIC	2.642	Down-regulation
CMGC_CDK_CDK4_CDK4_ST	P38398	BRCA1	P11802	CDK4	S510	R506S	506	Missense	distal	-4	no	3.301	3.300	EPSD	COSMIC	2.642	Down-regulation
CMGC_CDK_CDK4_CDK4_ST	P38398	BRCA1	P11802	CDK4	S510	R504C	504	Missense	distal	-6	no	3.301	3.406	EPSD	COSMIC	2.642	Up-regulation
CMGC_CDK_CDK4_CDK4_ST	P38398	BRCA1	P11802	CDK4	S510	S510L	510	Missense	central	0	yes	3.301	0.000	EPSD	COSMIC	2.642	Loss
CMGC_CDK_CDK4_CDK4_ST	P38398	BRCA1	P11802	CDK4	S510	L512F	512	Missense	proximal	2	no	3.301	3.228	EPSD	COSMIC	2.642	Down-regulation
CMGC_CDK_CDK4_CDK4_ST	P38398	BRCA1	P11802	CDK4	S510	R507K	507	Missense	distal	-3	no	3.301	3.279	EPSD	COSMIC	2.642	Down-regulation
CMGC_CDK_CDK4_CDK4_ST	P38398	BRCA1	P11802	CDK4	S510	R507I	507	Missense	distal	-3	no	3.301	3.383	EPSD	COSMIC	2.642	Up-regulation
CMGC_CDK_CDK4_CDK4_ST	P38398	BRCA1	P11802	CDK4	T528	G535R	535	Missense	distal	7	no	6.179	6.198	EPSD	COSMIC	2.642	Up-regulation
CMGC_CDK_CDK4_CDK4_ST	P38398	BRCA1	P11802	CDK4	T528	I532F	532	Missense	distal	4	no	6.179	6.186	EPSD	COSMIC	2.642	Up-regulation
CMGC_CDK_CDK4_CDK4_ST	P38398	BRCA1	P11802	CDK4	S632	N630H	630	Missense	proximal	-2	no	7.444	7.421	PhosphoSitePlus	COSMIC	2.642	Down-regulation
CMGC_CDK_CDK4_CDK4_ST	P38398	BRCA1	P11802	CDK4	S632	P633S	633	Missense	proximal	1	no	7.444	1.257	PhosphoSitePlus	COSMIC	2.642	Loss
CMGC_CDK_CDK4_CDK4_ST	P38398	BRCA1	P11802	CDK4	S632	P634S	634	Missense	proximal	2	no	7.444	7.603	PhosphoSitePlus	COSMIC	2.642	Up-regulation
CMGC_CDK_CDK4_CDK4_ST	P38398	BRCA1	P11802	CDK4	S632	S628N	628	Missense	distal	-4	no	7.444	7.445	PhosphoSitePlus	COSMIC	2.642	Up-regulation
CMGC_CDK_CDK4_CDK4_ST	P38398	BRCA1	P11802	CDK4	S632	T637N	637	Missense	distal	5	no	7.444	7.446	PhosphoSitePlus	COSMIC	2.642	Up-regulation
CMGC_CDK_CDK4_CDK4_ST	P38398	BRCA1	P11802	CDK4	S632	E638D	638	Missense	distal	6	no	7.444	7.380	PhosphoSitePlus	COSMIC	2.642	Down-regulation
CMGC_CDK_CDK4_CDK4_ST	P38398	BRCA1	P11802	CDK4	S632	C636F	636	Missense	distal	4	no	7.444	7.446	PhosphoSitePlus	COSMIC	2.642	Up-regulation
CMGC_CDK_CDK4_CDK4_ST	P38398	BRCA1	P11802	CDK4	S632	P634R	634	Missense	proximal	2	no	7.444	7.481	PhosphoSitePlus	COSMIC	2.642	Up-regulation
CMGC_CDK_CDK4_CDK4_ST	P38398	BRCA1	P11802	CDK4	S645	E648Q	648	Missense	distal	3	no	2.758	2.689	EPSD	COSMIC	2.642	Down-regulation
CMGC_CDK_CDK4_CDK4_ST	P38398	BRCA1	P11802	CDK4	S645	E649D	649	Missense	distal	4	no	2.758	2.924	EPSD	COSMIC	2.642	Up-regulation
CMGC_CDK_CDK4_CDK4_ST	P38398	BRCA1	P11802	CDK4	S645	E649Q	649	Missense	distal	4	no	2.758	2.829	EPSD	COSMIC	2.642	Up-regulation
CMGC_CDK_CDK4_CDK4_ST	P38398	BRCA1	P11802	CDK4	S645	E648K	648	Missense	distal	3	no	2.758	3.046	EPSD	COSMIC	2.642	Up-regulation
CMGC_CDK_CDK4_CDK4_ST	P38398	BRCA1	P11802	CDK4	S645	E638D	638	Missense	distal	-7	no	2.758	2.528	EPSD	COSMIC	2.642	Loss
CMGC_CDK_CDK4_CDK4_ST	P38398	BRCA1	P11802	CDK4	S645	D642H	642	Missense	distal	-3	no	2.758	2.729	EPSD	COSMIC	2.642	Down-regulation
CMGC_CDK_CDK4_CDK4_ST	P38398	BRCA1	P11802	CDK4	S645	K651N	651	Missense	distal	6	no	2.758	2.710	EPSD	COSMIC	2.642	Down-regulation
CMGC_CDK_CDK4_CDK4_ST	P38398	BRCA1	P11802	CDK4	S645	S647N	647	Missense	proximal	2	no	2.758	2.574	EPSD	COSMIC	2.642	Loss
CMGC_CDK_CDK4_CDK4_ST	P38398	BRCA1	P11802	CDK4	S708	N714D	714	Missense	distal	6	no	4.112	4.058	EPSD	COSMIC	2.642	Down-regulation
CMGC_CDK_CDK4_CDK4_ST	P38398	BRCA1	P11802	CDK4	S708	S708F	708	Missense	central	0	yes	4.112	0.000	EPSD	COSMIC	2.642	Loss
CMGC_CDK_CDK4_CDK4_ST	P38398	BRCA1	P11802	CDK4	S708	T710I	710	Missense	proximal	2	no	4.112	4.025	EPSD	COSMIC	2.642	Down-regulation
CMGC_CDK_CDK4_CDK4_ST	P38398	BRCA1	P11802	CDK4	S708	S708C	708	Missense	central	0	yes	4.112	0.000	EPSD	COSMIC	2.642	Loss
CMGC_CDK_CDK4_CDK4_ST	P38398	BRCA1	P11802	CDK4	S708	G707E	707	Missense	proximal	-1	no	4.112	3.786	EPSD	COSMIC	2.642	Down-regulation
CMGC_CDK_CDK4_CDK4_ST	P38398	BRCA1	P11802	CDK4	S713	N714D	714	Missense	proximal	1	no	2.914	2.414	EPSD	COSMIC	2.642	Loss
CMGC_CDK_CDK4_CDK4_ST	P38398	BRCA1	P11802	CDK4	S713	S708F	708	Missense	distal	-5	no	2.914	2.748	EPSD	COSMIC	2.642	Down-regulation
CMGC_CDK_CDK4_CDK4_ST	P38398	BRCA1	P11802	CDK4	S713	T710I	710	Missense	distal	-3	no	2.914	3.002	EPSD	COSMIC	2.642	Up-regulation
CMGC_CDK_CDK4_CDK4_ST	P38398	BRCA1	P11802	CDK4	S713	S708C	708	Missense	distal	-5	no	2.914	2.756	EPSD	COSMIC	2.642	Down-regulation
CMGC_CDK_CDK4_CDK4_ST	P38398	BRCA1	P11802	CDK4	S713	G707E	707	Missense	distal	-6	no	2.914	2.577	EPSD	COSMIC	2.642	Loss
CMGC_CDK_CDK4_CDK4_ST	P38398	BRCA1	P11802	CDK4	S713	S716F	716	Missense	distal	3	no	2.914	2.323	EPSD	COSMIC	2.642	Loss
CMGC_CDK_CDK4_CDK4_ST	P38398	BRCA1	P11802	CDK4	S753	L750I	750	Missense	distal	-3	no	2.984	2.988	EPSD	COSMIC	2.642	Up-regulation
CMGC_CDK_CDK4_CDK4_ST	P38398	BRCA1	P11802	CDK4	S753	V757A	757	Missense	distal	4	no	2.984	2.687	EPSD	COSMIC	2.642	Down-regulation
CMGC_CDK_CDK4_CDK4_ST	P38398	BRCA1	P11802	CDK4	S753	L758F	758	Missense	distal	5	no	2.984	2.980	EPSD	COSMIC	2.642	Down-regulation
CMGC_CDK_CDK4_CDK4_ST	P38398	BRCA1	P11802	CDK4	S753	G754E	754	Missense	proximal	1	no	2.984	1.586	EPSD	COSMIC	2.642	Loss
CMGC_CDK_CDK4_CDK4_ST	P38398	BRCA1	P11802	CDK4	S753	M751I	751	Missense	proximal	-2	no	2.984	2.926	EPSD	COSMIC	2.642	Down-regulation
CMGC_CDK_CDK4_CDK4_ST	P38398	BRCA1	P11802	CDK4	S767	S770L	770	Missense	distal	3	no	2.846	2.252	EPSD	COSMIC	2.642	Loss
CMGC_CDK_CDK4_CDK4_ST	P38398	BRCA1	P11802	CDK4	S767	S763F	763	Missense	distal	-4	no	2.846	2.847	EPSD	COSMIC;GDSC;CCLE	2.642	Up-regulation
CMGC_CDK_CDK4_CDK4_ST	P38398	BRCA1	P11802	CDK4	S767	P773S	773	Missense	distal	6	no	2.846	3.004	EPSD	COSMIC	2.642	Up-regulation
CMGC_CDK_CDK4_CDK4_ST	P38398	BRCA1	P11802	CDK4	S767	E765K	765	Missense	proximal	-2	no	2.846	2.901	EPSD	COSMIC	2.642	Up-regulation
CMGC_CDK_CDK4_CDK4_ST	P38398	BRCA1	P11802	CDK4	S767	V772A	772	Missense	distal	5	no	2.846	2.819	EPSD	COSMIC;GDSC	2.642	Down-regulation
CMGC_CDK_CDK4_CDK4_ST	P38398	BRCA1	P11802	CDK4	S868	P871L	871	Missense	distal	3	no	2.727	1.829	EPSD	COSMIC	2.642	Loss
CMGC_CDK_CDK4_CDK4_ST	P38398	BRCA1	P11802	CDK4	S868	S868L	868	Missense	central	0	yes	2.727	0.000	EPSD	COSMIC	2.642	Loss
CMGC_CDK_CDK4_CDK4_ST	P38398	BRCA1	P11802	CDK4	S868	S864L	864	Missense	distal	-4	no	2.727	2.729	EPSD	COSMIC	2.642	Up-regulation
CMGC_CDK_CDK4_CDK4_ST	P38398	BRCA1	P11802	CDK4	S868	K865N	865	Missense	distal	-3	no	2.727	2.745	EPSD	COSMIC	2.642	Up-regulation
CMGC_CDK_CDK4_CDK4_ST	P38398	BRCA1	P11802	CDK4	S896	Q895R	895	Missense	proximal	-1	no	7.792	7.687	EPSD	COSMIC	2.642	Down-regulation
CMGC_CDK_CDK4_CDK4_ST	P38398	BRCA1	P11802	CDK4	S896	G890W	890	Missense	distal	-6	no	7.792	7.610	EPSD	COSMIC	2.642	Down-regulation
CMGC_CDK_CDK4_CDK4_ST	P38398	BRCA1	P11802	CDK4	S896	G890V	890	Missense	distal	-6	no	7.792	7.600	EPSD	COSMIC;GDSC;CCLE	2.642	Down-regulation
CMGC_CDK_CDK4_CDK4_ST	P38398	BRCA1	P11802	CDK4	S896	E902Q	902	Missense	distal	6	no	7.792	7.762	EPSD	COSMIC	2.642	Down-regulation
CMGC_CDK_CDK4_CDK4_ST	P38398	BRCA1	P11802	CDK4	S896	G890R	890	Missense	distal	-6	no	7.792	7.515	EPSD	COSMIC	2.642	Down-regulation
CMGC_CDK_CDK4_CDK4_ST	P38398	BRCA1	P11802	CDK4	S896	K898E	898	Missense	proximal	2	no	7.792	7.707	EPSD	COSMIC	2.642	Down-regulation
CMGC_CDK_CDK4_CDK4_ST	P38398	BRCA1	P11802	CDK4	T967	E962K	962	Missense	distal	-5	no	7.182	7.169	EPSD	COSMIC;GDSC;CCLE	2.642	Down-regulation
CMGC_CDK_CDK4_CDK4_ST	P38398	BRCA1	P11802	CDK4	T967	T967I	967	Missense	central	0	yes	7.182	0.000	EPSD	COSMIC	2.642	Loss
CMGC_CDK_CDK4_CDK4_ST	P38398	BRCA1	P11802	CDK4	T967	N969I	969	Missense	proximal	2	no	7.182	7.090	EPSD	COSMIC	2.642	Down-regulation
CMGC_CDK_CDK4_CDK4_ST	P38398	BRCA1	P11802	CDK4	S1009	E1011K	1011	Missense	proximal	2	no	8.180	8.265	EPSD	COSMIC	2.642	Up-regulation
CMGC_CDK_CDK4_CDK4_ST	P38398	BRCA1	P11802	CDK4	S1009	M1008I	1008	Missense	proximal	-1	no	8.180	8.206	EPSD	COSMIC;GDSC	2.642	Up-regulation
CMGC_CDK_CDK4_CDK4_ST	P38398	BRCA1	P11802	CDK4	S1009	M1014I	1014	Missense	distal	5	no	8.180	8.187	EPSD	COSMIC;GDSC;CCLE	2.642	Up-regulation
CMGC_CDK_CDK4_CDK4_ST	P38398	BRCA1	P11802	CDK4	S1009	M1014K	1014	Missense	distal	5	no	8.180	8.166	EPSD	COSMIC	2.642	Down-regulation
CMGC_CDK_CDK4_CDK4_ST	P38398	BRCA1	P11802	CDK4	S1009	N1016I	1016	Missense	distal	7	no	8.180	8.169	EPSD	COSMIC	2.642	Down-regulation
CMGC_CDK_CDK4_CDK4_ST	P38398	BRCA1	P11802	CDK4	S1009	S1009F	1009	Missense	central	0	yes	8.180	0.000	EPSD	COSMIC	2.642	Loss
CMGC_CDK_CDK4_CDK4_ST	P38398	BRCA1	P11802	CDK4	S1009	E1013D	1013	Missense	distal	4	no	8.180	8.346	EPSD	COSMIC	2.642	Up-regulation
CMGC_CDK_CDK4_CDK4_ST	P38398	BRCA1	P11802	CDK4	S1021	S1024T	1024	Missense	distal	3	no	2.975	2.485	EPSD	COSMIC	2.642	Loss
CMGC_CDK_CDK4_CDK4_ST	P38398	BRCA1	P11802	CDK4	S1021	M1014I	1014	Missense	distal	-7	no	2.975	2.955	EPSD	COSMIC;GDSC;CCLE	2.642	Down-regulation
CMGC_CDK_CDK4_CDK4_ST	P38398	BRCA1	P11802	CDK4	S1021	R1028H	1028	Missense	distal	7	no	2.975	2.968	EPSD	COSMIC	2.642	Down-regulation
CMGC_CDK_CDK4_CDK4_ST	P38398	BRCA1	P11802	CDK4	S1021	M1014K	1014	Missense	distal	-7	no	2.975	3.171	EPSD	COSMIC	2.642	Up-regulation
CMGC_CDK_CDK4_CDK4_ST	P38398	BRCA1	P11802	CDK4	S1021	P1020L	1020	Missense	proximal	-1	no	2.975	3.012	EPSD	COSMIC	2.642	Up-regulation
CMGC_CDK_CDK4_CDK4_ST	P38398	BRCA1	P11802	CDK4	S1021	N1016I	1016	Missense	distal	-5	no	2.975	2.931	EPSD	COSMIC	2.642	Down-regulation
CMGC_CDK_CDK4_CDK4_ST	P38398	BRCA1	P11802	CDK4	S1189	K1183R	1183	Missense	distal	-6	no	9.469	9.507	EPSD	COSMIC	2.642	Up-regulation
CMGC_CDK_CDK4_CDK4_ST	P38398	BRCA1	P11802	CDK4	S1189	P1190H	1190	Missense	proximal	1	no	9.469	2.886	EPSD	COSMIC;GDSC;CCLE	2.642	Down-regulation
CMGC_CDK_CDK4_CDK4_ST	P38398	BRCA1	P11802	CDK4	S1189	P1190F	1190	Missense	proximal	1	no	9.469	3.804	EPSD	COSMIC	2.642	Down-regulation
CMGC_CDK_CDK4_CDK4_ST	P38398	BRCA1	P11802	CDK4	S1189	Q1182H	1182	Missense	distal	-7	no	9.469	9.379	EPSD	COSMIC	2.642	Down-regulation
CMGC_CDK_CDK4_CDK4_ST	P38398	BRCA1	P11802	CDK4	S1189	P1192F	1192	Missense	distal	3	no	9.469	8.573	EPSD	COSMIC	2.642	Down-regulation
CMGC_CDK_CDK4_CDK4_ST	P38398	BRCA1	P11802	CDK4	S1189	P1190L	1190	Missense	proximal	1	no	9.469	1.890	EPSD	COSMIC	2.642	Loss
CMGC_CDK_CDK4_CDK4_ST	P38398	BRCA1	P11802	CDK4	S1189	P1192S	1192	Missense	distal	3	no	9.469	9.164	EPSD	COSMIC	2.642	Down-regulation
CMGC_CDK_CDK4_CDK4_ST	P38398	BRCA1	P11802	CDK4	S1189	P1192L	1192	Missense	distal	3	no	9.469	8.570	EPSD	COSMIC	2.642	Down-regulation
CMGC_CDK_CDK4_CDK4_ST	P38398	BRCA1	P11802	CDK4	S1189	R1188K	1188	Missense	proximal	-1	no	9.469	9.423	EPSD	COSMIC	2.642	Down-regulation
CMGC_CDK_CDK4_CDK4_ST	P38398	BRCA1	P11802	CDK4	S1191	E1185Q	1185	Missense	distal	-6	no	8.595	8.661	EPSD	COSMIC	2.642	Up-regulation
CMGC_CDK_CDK4_CDK4_ST	P38398	BRCA1	P11802	CDK4	S1191	P1190H	1190	Missense	proximal	-1	no	8.595	8.641	EPSD	COSMIC;GDSC;CCLE	2.642	Up-regulation
CMGC_CDK_CDK4_CDK4_ST	P38398	BRCA1	P11802	CDK4	S1191	P1190F	1190	Missense	proximal	-1	no	8.595	8.715	EPSD	COSMIC	2.642	Up-regulation
CMGC_CDK_CDK4_CDK4_ST	P38398	BRCA1	P11802	CDK4	S1191	P1192F	1192	Missense	proximal	1	no	8.595	2.931	EPSD	COSMIC	2.642	Down-regulation
CMGC_CDK_CDK4_CDK4_ST	P38398	BRCA1	P11802	CDK4	S1191	P1190L	1190	Missense	proximal	-1	no	8.595	8.633	EPSD	COSMIC	2.642	Up-regulation
CMGC_CDK_CDK4_CDK4_ST	P38398	BRCA1	P11802	CDK4	S1191	P1192S	1192	Missense	proximal	1	no	8.595	2.408	EPSD	COSMIC	2.642	Loss
CMGC_CDK_CDK4_CDK4_ST	P38398	BRCA1	P11802	CDK4	S1191	P1192L	1192	Missense	proximal	1	no	8.595	1.016	EPSD	COSMIC	2.642	Loss
CMGC_CDK_CDK4_CDK4_ST	P38398	BRCA1	P11802	CDK4	S1191	R1188K	1188	Missense	distal	-3	no	8.595	8.574	EPSD	COSMIC	2.642	Down-regulation
CMGC_CDK_CDK4_CDK4_ST	P38398	BRCA1	P11802	CDK4	S1191	H1197Y	1197	Missense	distal	6	no	8.595	8.612	EPSD	COSMIC	2.642	Up-regulation
CMGC_CDK_CDK4_CDK4_ST	P38398	BRCA1	P11802	CDK4	S1211	S1212P	1212	Missense	proximal	1	no	1.038	7.225	EPSD	COSMIC	2.642	Gain
CMGC_CDK_CDK4_CDK4_ST	P38398	BRCA1	P11802	CDK4	S1480	S1483C	1483	Missense	distal	3	no	3.236	2.553	EPSD	COSMIC	2.642	Loss
CMGC_CDK_CDK4_CDK4_ST	P38398	BRCA1	P11802	CDK4	S1480	E1478Q	1478	Missense	proximal	-2	no	3.236	3.214	EPSD	COSMIC	2.642	Down-regulation
CMGC_CDK_CDK4_CDK4_ST	P38398	BRCA1	P11802	CDK4	S1480	S1473Y	1473	Missense	distal	-7	no	3.236	2.639	EPSD	COSMIC	2.642	Loss
CMGC_CDK_CDK4_CDK4_ST	P38398	BRCA1	P11802	CDK4	S1480	T1485S	1485	Missense	distal	5	no	3.236	3.214	EPSD	COSMIC	2.642	Down-regulation
CMGC_CDK_CDK4_CDK4_ST	P38398	BRCA1	P11802	CDK4	S1480	S1473F	1473	Missense	distal	-7	no	3.236	2.523	EPSD	COSMIC	2.642	Loss
CMGC_CDK_CDK4_CDK4_ST	P38398	BRCA1	P11802	CDK4	S1480	D1475E	1475	Missense	distal	-5	no	3.236	3.284	EPSD	COSMIC	2.642	Up-regulation
CMGC_CDK_CDK4_CDK4_ST	P38398	BRCA1	P11802	CDK4	S1496	S1497P	1497	Missense	proximal	1	no	1.757	7.944	EPSD	COSMIC	2.642	Gain
CMGC_CDK_CDK4_CDK4_ST	P38398	BRCA1	P11802	CDK4	S1497	P1491L	1491	Missense	distal	-6	no	9.124	9.277	EPSD	COSMIC	2.642	Up-regulation
CMGC_CDK_CDK4_CDK4_ST	P38398	BRCA1	P11802	CDK4	S1497	P1502L	1502	Missense	distal	5	no	9.124	9.175	EPSD	COSMIC	2.642	Up-regulation
CMGC_CDK_CDK4_CDK4_ST	P38398	BRCA1	P11802	CDK4	S1497	S1499F	1499	Missense	proximal	2	no	9.124	8.824	EPSD	COSMIC	2.642	Down-regulation
CMGC_CDK_CDK4_CDK4_ST	P38398	BRCA1	P11802	CDK4	S1497	E1490Q	1490	Missense	distal	-7	no	9.124	8.963	EPSD	COSMIC	2.642	Down-regulation
CMGC_CDK_CDK4_CDK4_ST	P38398	BRCA1	P11802	CDK4	S1497	S1497P	1497	Missense	central	0	yes	9.124	0.000	EPSD	COSMIC	2.642	Loss
CMGC_CDK_CDK4_CDK4_ST	P38398	BRCA1	P11802	CDK4	S1514	S1512I	1512	Missense	proximal	-2	no	2.872	2.643	EPSD	COSMIC	2.642	Down-regulation
CMGC_CDK_CDK4_CDK4_ST	P38398	BRCA1	P11802	CDK4	S1514	W1508C	1508	Missense	distal	-6	no	2.872	2.882	EPSD	COSMIC	2.642	Up-regulation
CMGC_CDK_CDK4_CDK4_ST	P38398	BRCA1	P11802	CDK4	S1514	N1519S	1519	Missense	distal	5	no	2.872	2.848	EPSD	COSMIC	2.642	Down-regulation
CMGC_CDK_CDK4_CDK4_ST	P38398	BRCA1	P11802	CDK4	S1514	G1515E	1515	Missense	proximal	1	no	2.872	1.474	EPSD	COSMIC	2.642	Loss
CMGC_CDK_CDK4_CDK4_ST	P38398	BRCA1	P11802	CDK4	S1514	L1517V	1517	Missense	distal	3	no	2.872	2.714	EPSD	COSMIC	2.642	Down-regulation
CMGC_CDK_CDK4_CDK4_ST	P38398	BRCA1	P11802	CDK4	S1514	L1517P	1517	Missense	distal	3	no	2.872	3.771	EPSD	COSMIC	2.642	Up-regulation
CMGC_CDK_CDK4_CDK4_ST	P38398	BRCA1	P11802	CDK4	S1516	L1517P	1517	Missense	proximal	1	no	1.261	8.840	EPSD	COSMIC	2.642	Gain
CMGC_CDK_CDK4_CDK4_ST	P38398	BRCA1	P11802	CDK4	S1551	D1546Y	1546	Missense	distal	-5	no	3.482	3.488	EPSD	COSMIC	2.642	Up-regulation
CMGC_CDK_CDK4_CDK4_ST	P38398	BRCA1	P11802	CDK4	S1551	D1546N	1546	Missense	distal	-5	no	3.482	3.515	EPSD	COSMIC;GDSC	2.642	Up-regulation
CMGC_CDK_CDK4_CDK4_ST	P38398	BRCA1	P11802	CDK4	S1551	S1551C	1551	Missense	central	0	yes	3.482	0.000	EPSD	COSMIC	2.642	Loss
CMGC_CDK_CDK4_CDK4_ST	P38398	BRCA1	P11802	CDK4	S1551	T1548M	1548	Missense	distal	-3	no	3.482	3.541	EPSD	COSMIC;GDSC;CCLE	2.642	Up-regulation
CMGC_CDK_CDK4_CDK4_ST	P38398	BRCA1	P11802	CDK4	S1551	L1558I	1558	Missense	distal	7	no	3.482	3.481	EPSD	COSMIC	2.642	Down-regulation
CMGC_CDK_CDK4_CDK4_ST	P38398	BRCA1	P11802	CDK4	T1561	L1564P	1564	Missense	distal	3	no	8.173	9.072	EPSD	COSMIC	2.642	Up-regulation
CMGC_CDK_CDK4_CDK4_ST	P38398	BRCA1	P11802	CDK4	T1561	L1558I	1558	Missense	distal	-3	no	8.173	8.177	EPSD	COSMIC	2.642	Up-regulation
CMGC_CDK_CDK4_CDK4_ST	P38398	BRCA1	P11802	CDK4	T1561	P1562L	1562	Missense	proximal	1	no	8.173	0.594	EPSD	COSMIC	2.642	Loss
CMGC_CDK_CDK4_CDK4_ST	P38398	BRCA1	P11802	CDK4	T1561	P1562T	1562	Missense	proximal	1	no	8.173	1.647	EPSD	COSMIC	2.642	Loss
CMGC_CDK_CDK4_CDK4_ST	P38398	BRCA1	P11802	CDK4	T1561	I1568S	1568	Missense	distal	7	no	8.173	8.199	EPSD	COSMIC	2.642	Up-regulation
CMGC_CDK_CDK4_CDK4_ST	P38398	BRCA1	P11802	CDK4	T1561	S1566G	1566	Missense	distal	5	no	8.173	8.221	EPSD	COSMIC	2.642	Up-regulation
CMGC_CDK_CDK4_CDK4_ST	P38398	BRCA1	P11802	CDK4	S1566	S1569G	1569	Missense	distal	3	no	3.003	2.200	EPSD	COSMIC	2.642	Loss
CMGC_CDK_CDK4_CDK4_ST	P38398	BRCA1	P11802	CDK4	S1566	L1564P	1564	Missense	proximal	-2	no	3.003	3.532	EPSD	COSMIC	2.642	Up-regulation
CMGC_CDK_CDK4_CDK4_ST	P38398	BRCA1	P11802	CDK4	S1566	P1562L	1562	Missense	distal	-4	no	3.003	3.004	EPSD	COSMIC	2.642	Up-regulation
CMGC_CDK_CDK4_CDK4_ST	P38398	BRCA1	P11802	CDK4	S1566	L1570P	1570	Missense	distal	4	no	3.003	2.842	EPSD	COSMIC	2.642	Down-regulation
CMGC_CDK_CDK4_CDK4_ST	P38398	BRCA1	P11802	CDK4	S1566	P1562T	1562	Missense	distal	-4	no	3.003	3.004	EPSD	COSMIC	2.642	Up-regulation
CMGC_CDK_CDK4_CDK4_ST	P38398	BRCA1	P11802	CDK4	S1566	I1568S	1568	Missense	proximal	2	no	3.003	3.279	EPSD	COSMIC	2.642	Up-regulation
CMGC_CDK_CDK4_CDK4_ST	P38398	BRCA1	P11802	CDK4	S1566	S1566G	1566	Missense	central	0	yes	3.003	0.000	EPSD	COSMIC	2.642	Loss
CMGC_CDK_CDK4_CDK4_ST	P38398	BRCA1	P11802	CDK4	S1566	S1572C	1572	Missense	distal	6	no	3.003	2.786	EPSD	COSMIC	2.642	Down-regulation
CMGC_CDK_CDK4_CDK4_ST	P38398	BRCA1	P11802	CDK4	S1566	S1572T	1572	Missense	distal	6	no	3.003	2.881	EPSD	COSMIC	2.642	Down-regulation
CMGC_CDK_CDK4_CDK4_ST	P38398	BRCA1	P11802	CDK4	S1569	L1570P	1570	Missense	proximal	1	no	1.852	9.431	EPSD	COSMIC	2.642	Gain
CMGC_CDK_CDK4_CDK4_ST	P38398	BRCA1	P11802	CDK4	T1597	S1598P	1598	Missense	proximal	1	no	0.409	6.596	EPSD	COSMIC	2.642	Gain
CMGC_CDK_CDK4_CDK4_ST	P38398	BRCA1	P11802	CDK4	S1613	S1613G	1613	Missense	central	0	yes	8.365	0.000	EPSD	COSMIC	2.642	Loss
CMGC_CDK_CDK4_CDK4_ST	P38398	BRCA1	P11802	CDK4	S1613	T1619S	1619	Missense	distal	6	no	8.365	8.487	EPSD	COSMIC	2.642	Up-regulation
CMGC_CDK_CDK4_CDK4_ST	P38398	BRCA1	P11802	CDK4	S1613	A1608T	1608	Missense	distal	-5	no	8.365	8.316	EPSD	COSMIC	2.642	Down-regulation
CMGC_CDK_CDK4_CDK4_ST	P38398	BRCA1	P11802	CDK4	S1613	Q1612H	1612	Missense	proximal	-1	no	8.365	8.410	EPSD	COSMIC	2.642	Up-regulation
CMGC_CDK_CDK4_CDK4_ST	P38398	BRCA1	P11802	CDK4	S1613	A1615V	1615	Missense	proximal	2	no	8.365	8.188	EPSD	COSMIC	2.642	Down-regulation
CMGC_CDK_CDK4_CDK4_ST	P38398	BRCA1	P11802	CDK4	S1613	V1607M	1607	Missense	distal	-6	no	8.365	8.330	EPSD	COSMIC	2.642	Down-regulation
CMGC_CDK_CDK4_CDK4_ST	P38398	BRCA1	P11802	CDK4	S1613	V1607E	1607	Missense	distal	-6	no	8.365	8.219	EPSD	COSMIC	2.642	Down-regulation
CMGC_CDK_CDK4_CDK4_ST	P38398	BRCA1	P11802	CDK4	T1658	P1659Q	1659	Missense	proximal	1	no	7.397	0.228	EPSD	COSMIC	2.642	Loss
CMGC_CDK_CDK4_CDK4_ST	P38398	BRCA1	P11802	CDK4	T1658	P1659L	1659	Missense	proximal	1	no	7.397	-0.182	EPSD	COSMIC	2.642	Loss
CMGC_CDK_CDK4_CDK4_ST	P38398	BRCA1	P11802	CDK4	T1658	M1652I	1652	Missense	distal	-6	no	7.397	7.444	EPSD	COSMIC	2.642	Up-regulation
CMGC_CDK_CDK4_CDK4_ST	P38398	BRCA1	P11802	CDK4	T1658	S1651F	1651	Missense	distal	-7	no	7.397	6.684	EPSD	COSMIC	2.642	Down-regulation
CMGC_CDK_CDK4_CDK4_ST	P38398	BRCA1	P11802	CDK4	T1658	V1654E	1654	Missense	distal	-4	no	7.397	7.396	EPSD	COSMIC	2.642	Down-regulation
CMGC_CDK_CDK4_CDK4_ST	P38398	BRCA1	P11802	CDK4	T1658	M1663V	1663	Missense	distal	5	no	7.397	7.405	EPSD	COSMIC	2.642	Up-regulation
CMGC_CDK_CDK4_CDK4_ST	P38398	BRCA1	P11802	CDK4	T1658	V1653A	1653	Missense	distal	-5	no	7.397	7.503	EPSD	COSMIC	2.642	Up-regulation
CMGC_CDK_CDK4_CDK4_ST	P38398	BRCA1	P11802	CDK4	T1658	E1661K	1661	Missense	distal	3	no	7.397	7.685	EPSD	COSMIC	2.642	Up-regulation
CMGC_CDK_CDK4_CDK4_ST	Q96KS0	EGLN2	P11802	CDK4	S74	G79S	79	Missense	distal	5	no	7.682	7.634	EPSD	COSMIC	2.642	Down-regulation
CMGC_CDK_CDK4_CDK4_ST	Q96KS0	EGLN2	P11802	CDK4	S130	A128D	128	Missense	proximal	-2	no	6.672	6.565	PhosphoSitePlus	COSMIC	2.642	Down-regulation
CMGC_CDK_CDK4_CDK4_ST	Q96KS0	EGLN2	P11802	CDK4	S130	P129L	129	Missense	proximal	-1	no	6.672	6.709	PhosphoSitePlus	COSMIC	2.642	Up-regulation
CMGC_CDK_CDK4_CDK4_ST	Q96KS0	EGLN2	P11802	CDK4	T405	P403Q	403	Missense	proximal	-2	no	6.833	6.353	EPSD	COSMIC	2.642	Down-regulation
CMGC_CDK_CDK4_CDK4_ST	Q96KS0	EGLN2	P11802	CDK4	T405	T405M	405	Missense	central	0	yes	6.833	0.000	EPSD	COSMIC;GDSC	2.642	Loss
CMGC_CDK_CDK4_CDK4_ST	P15923	TCF3	P11802	CDK4	S55	G62S	62	Missense	distal	7	no	2.813	2.847	EPSD	COSMIC	2.642	Up-regulation
CMGC_CDK_CDK4_CDK4_ST	P15923	TCF3	P11802	CDK4	S55	R53W	53	Missense	proximal	-2	no	2.813	2.736	EPSD	COSMIC	2.642	Down-regulation
CMGC_CDK_CDK4_CDK4_ST	P15923	TCF3	P11802	CDK4	S55	S58F	58	Missense	distal	3	no	2.813	2.222	EPSD	COSMIC	2.642	Loss
CMGC_CDK_CDK4_CDK4_ST	P15923	TCF3	P11802	CDK4	S134	E129K	129	Missense	distal	-5	no	9.027	9.014	EPSD	COSMIC	2.642	Down-regulation
CMGC_CDK_CDK4_CDK4_ST	P15923	TCF3	P11802	CDK4	S134	S139F	139	Missense	distal	5	no	9.027	9.059	EPSD	COSMIC	2.642	Up-regulation
CMGC_CDK_CDK4_CDK4_ST	P15923	TCF3	P11802	CDK4	S134	S141L	141	Missense	distal	7	no	9.027	9.002	EPSD	COSMIC	2.642	Down-regulation
CMGC_CDK_CDK4_CDK4_ST	P15923	TCF3	P11802	CDK4	S134	P135L	135	Missense	proximal	1	no	9.027	1.448	EPSD	COSMIC	2.642	Loss
CMGC_CDK_CDK4_CDK4_ST	P15923	TCF3	P11802	CDK4	S139	S139F	139	Missense	central	0	yes	8.524	0.000	EPSD;PhosphoSitePlus	COSMIC	2.642	Loss
CMGC_CDK_CDK4_CDK4_ST	P15923	TCF3	P11802	CDK4	S139	S141L	141	Missense	proximal	2	no	8.524	8.296	EPSD;PhosphoSitePlus	COSMIC	2.642	Down-regulation
CMGC_CDK_CDK4_CDK4_ST	P15923	TCF3	P11802	CDK4	S139	P135L	135	Missense	distal	-4	no	8.524	8.525	EPSD;PhosphoSitePlus	COSMIC	2.642	Up-regulation
CMGC_CDK_CDK4_CDK4_ST	P15923	TCF3	P11802	CDK4	S141	S139F	139	Missense	proximal	-2	no	4.069	3.944	EPSD	COSMIC	2.642	Down-regulation
CMGC_CDK_CDK4_CDK4_ST	P15923	TCF3	P11802	CDK4	S141	Q148L	148	Missense	distal	7	no	4.069	4.064	EPSD	COSMIC	2.642	Down-regulation
CMGC_CDK_CDK4_CDK4_ST	P15923	TCF3	P11802	CDK4	S141	S141L	141	Missense	central	0	yes	4.069	0.000	EPSD	COSMIC	2.642	Loss
CMGC_CDK_CDK4_CDK4_ST	P15923	TCF3	P11802	CDK4	S141	P135L	135	Missense	distal	-6	no	4.069	4.222	EPSD	COSMIC	2.642	Up-regulation
CMGC_CDK_CDK4_CDK4_ST	P15923	TCF3	P11802	CDK4	T146	S139F	139	Missense	distal	-7	no	2.853	2.140	EPSD	COSMIC	2.642	Loss
CMGC_CDK_CDK4_CDK4_ST	P15923	TCF3	P11802	CDK4	T146	Y153C	153	Missense	distal	7	no	2.853	2.847	EPSD	COSMIC	2.642	Down-regulation
CMGC_CDK_CDK4_CDK4_ST	P15923	TCF3	P11802	CDK4	T146	Q148L	148	Missense	proximal	2	no	2.853	2.855	EPSD	COSMIC	2.642	Up-regulation
CMGC_CDK_CDK4_CDK4_ST	P15923	TCF3	P11802	CDK4	T146	P151L	151	Missense	distal	5	no	2.853	2.903	EPSD	COSMIC	2.642	Up-regulation
CMGC_CDK_CDK4_CDK4_ST	P15923	TCF3	P11802	CDK4	T146	S141L	141	Missense	distal	-5	no	2.853	2.701	EPSD	COSMIC	2.642	Down-regulation
CMGC_CDK_CDK4_CDK4_ST	P15923	TCF3	P11802	CDK4	S154	A161V	161	Missense	distal	7	no	5.149	5.134	EPSD	COSMIC	2.642	Down-regulation
CMGC_CDK_CDK4_CDK4_ST	P15923	TCF3	P11802	CDK4	S154	Y153C	153	Missense	proximal	-1	no	5.149	5.242	EPSD	COSMIC	2.642	Up-regulation
CMGC_CDK_CDK4_CDK4_ST	P15923	TCF3	P11802	CDK4	S154	G155S	155	Missense	proximal	1	no	5.149	4.764	EPSD	COSMIC	2.642	Down-regulation
CMGC_CDK_CDK4_CDK4_ST	P15923	TCF3	P11802	CDK4	S154	Q148L	148	Missense	distal	-6	no	5.149	5.236	EPSD	COSMIC	2.642	Up-regulation
CMGC_CDK_CDK4_CDK4_ST	P15923	TCF3	P11802	CDK4	S154	P151L	151	Missense	distal	-3	no	5.149	5.407	EPSD	COSMIC	2.642	Up-regulation
CMGC_CDK_CDK4_CDK4_ST	P15923	TCF3	P11802	CDK4	S154	A161T	161	Missense	distal	7	no	5.149	5.143	EPSD	COSMIC	2.642	Down-regulation
CMGC_CDK_CDK4_CDK4_ST	P15923	TCF3	P11802	CDK4	S182	P186L	186	Missense	distal	4	no	2.552	2.712	EPSD	COSMIC	2.642	Gain
CMGC_CDK_CDK4_CDK4_ST	P15923	TCF3	P11802	CDK4	S202	A203T	203	Missense	proximal	1	no	2.663	3.074	EPSD	COSMIC	2.642	Up-regulation
CMGC_CDK_CDK4_CDK4_ST	P15923	TCF3	P11802	CDK4	S202	A197T	197	Missense	distal	-5	no	2.663	2.614	EPSD	COSMIC	2.642	Loss
CMGC_CDK_CDK4_CDK4_ST	P15923	TCF3	P11802	CDK4	T205	A203T	203	Missense	proximal	-2	no	7.694	7.673	EPSD	COSMIC	2.642	Down-regulation
CMGC_CDK_CDK4_CDK4_ST	P15923	TCF3	P11802	CDK4	T205	A212T	212	Missense	distal	7	no	7.694	7.688	EPSD	COSMIC	2.642	Down-regulation
CMGC_CDK_CDK4_CDK4_ST	P15923	TCF3	P11802	CDK4	S229	P230S	230	Missense	proximal	1	no	8.112	1.925	EPSD	COSMIC	2.642	Loss
CMGC_CDK_CDK4_CDK4_ST	P15923	TCF3	P11802	CDK4	S244	P248S	248	Missense	distal	4	no	3.540	3.333	EPSD	COSMIC	2.642	Down-regulation
CMGC_CDK_CDK4_CDK4_ST	P15923	TCF3	P11802	CDK4	S244	S244L	244	Missense	central	0	yes	3.540	0.000	EPSD	COSMIC	2.642	Loss
CMGC_CDK_CDK4_CDK4_ST	P15923	TCF3	P11802	CDK4	S245	P248S	248	Missense	distal	3	no	9.863	9.559	PhosphoSitePlus;EPSD	COSMIC	2.642	Down-regulation
CMGC_CDK_CDK4_CDK4_ST	P15923	TCF3	P11802	CDK4	S245	G252S	252	Missense	distal	7	no	9.863	9.897	PhosphoSitePlus;EPSD	COSMIC	2.642	Up-regulation
CMGC_CDK_CDK4_CDK4_ST	P15923	TCF3	P11802	CDK4	S245	S244L	244	Missense	proximal	-1	no	9.863	10.149	PhosphoSitePlus;EPSD	COSMIC	2.642	Up-regulation
CMGC_CDK_CDK4_CDK4_ST	P15923	TCF3	P11802	CDK4	S253	P255Q	255	Missense	proximal	2	no	4.675	4.604	EPSD	COSMIC	2.642	Down-regulation
CMGC_CDK_CDK4_CDK4_ST	P15923	TCF3	P11802	CDK4	S253	P248S	248	Missense	distal	-5	no	4.675	4.811	EPSD	COSMIC	2.642	Up-regulation
CMGC_CDK_CDK4_CDK4_ST	P15923	TCF3	P11802	CDK4	S253	G252S	252	Missense	proximal	-1	no	4.675	4.159	EPSD	COSMIC	2.642	Down-regulation
CMGC_CDK_CDK4_CDK4_ST	P15923	TCF3	P11802	CDK4	S294	S295L	295	Missense	proximal	1	no	2.991	1.599	EPSD	COSMIC	2.642	Loss
CMGC_CDK_CDK4_CDK4_ST	P15923	TCF3	P11802	CDK4	S294	P288S	288	Missense	distal	-6	no	2.991	2.782	EPSD	COSMIC	2.642	Down-regulation
CMGC_CDK_CDK4_CDK4_ST	P15923	TCF3	P11802	CDK4	S294	S292F	292	Missense	proximal	-2	no	2.991	2.866	EPSD	COSMIC	2.642	Down-regulation
CMGC_CDK_CDK4_CDK4_ST	P15923	TCF3	P11802	CDK4	S294	S295N	295	Missense	proximal	1	no	2.991	2.492	EPSD	COSMIC	2.642	Loss
CMGC_CDK_CDK4_CDK4_ST	P15923	TCF3	P11802	CDK4	S294	S292I	292	Missense	proximal	-2	no	2.991	2.763	EPSD	COSMIC	2.642	Down-regulation
CMGC_CDK_CDK4_CDK4_ST	P15923	TCF3	P11802	CDK4	S306	P309L	309	Missense	distal	3	no	2.964	2.065	EPSD	COSMIC;CCLE	2.642	Loss
CMGC_CDK_CDK4_CDK4_ST	P15923	TCF3	P11802	CDK4	S306	G313V	313	Missense	distal	7	no	2.964	2.973	EPSD	COSMIC	2.642	Up-regulation
CMGC_CDK_CDK4_CDK4_ST	P15923	TCF3	P11802	CDK4	S306	G313R	313	Missense	distal	7	no	2.964	2.983	EPSD	COSMIC	2.642	Up-regulation
CMGC_CDK_CDK4_CDK4_ST	P15923	TCF3	P11802	CDK4	T308	P309L	309	Missense	proximal	1	no	7.602	0.023	EPSD	COSMIC;CCLE	2.642	Loss
CMGC_CDK_CDK4_CDK4_ST	P15923	TCF3	P11802	CDK4	T308	G313V	313	Missense	distal	5	no	7.602	7.596	EPSD	COSMIC	2.642	Down-regulation
CMGC_CDK_CDK4_CDK4_ST	P15923	TCF3	P11802	CDK4	T308	G313R	313	Missense	distal	5	no	7.602	7.577	EPSD	COSMIC	2.642	Down-regulation
CMGC_CDK_CDK4_CDK4_ST	P15923	TCF3	P11802	CDK4	S312	P309L	309	Missense	distal	-3	no	3.102	3.360	EPSD	COSMIC;CCLE	2.642	Up-regulation
CMGC_CDK_CDK4_CDK4_ST	P15923	TCF3	P11802	CDK4	S312	L317R	317	Missense	distal	5	no	3.102	3.088	EPSD	COSMIC	2.642	Down-regulation
CMGC_CDK_CDK4_CDK4_ST	P15923	TCF3	P11802	CDK4	S312	G313V	313	Missense	proximal	1	no	3.102	1.575	EPSD	COSMIC	2.642	Loss
CMGC_CDK_CDK4_CDK4_ST	P15923	TCF3	P11802	CDK4	S312	G313R	313	Missense	proximal	1	no	3.102	2.116	EPSD	COSMIC	2.642	Loss
CMGC_CDK_CDK4_CDK4_ST	P15923	TCF3	P11802	CDK4	S341	S346N	346	Missense	distal	5	no	6.916	6.940	EPSD	COSMIC	2.642	Up-regulation
CMGC_CDK_CDK4_CDK4_ST	P15923	TCF3	P11802	CDK4	S352	S346N	346	Missense	distal	-6	no	8.901	9.113	EPSD	COSMIC	2.642	Up-regulation
CMGC_CDK_CDK4_CDK4_ST	P15923	TCF3	P11802	CDK4	S352	P353L	353	Missense	proximal	1	no	8.901	1.321	EPSD	COSMIC;CCLE	2.642	Loss
CMGC_CDK_CDK4_CDK4_ST	P15923	TCF3	P11802	CDK4	T355	P353L	353	Missense	proximal	-2	no	7.412	6.884	EPSD	COSMIC;CCLE	2.642	Down-regulation
CMGC_CDK_CDK4_CDK4_ST	P15923	TCF3	P11802	CDK4	T355	G362D	362	Missense	distal	7	no	7.412	7.422	EPSD	COSMIC	2.642	Up-regulation
CMGC_CDK_CDK4_CDK4_ST	P15923	TCF3	P11802	CDK4	S359	P353L	353	Missense	distal	-6	no	8.056	8.209	EPSD	COSMIC;CCLE	2.642	Up-regulation
CMGC_CDK_CDK4_CDK4_ST	P15923	TCF3	P11802	CDK4	S359	T366M	366	Missense	distal	7	no	8.056	8.049	EPSD	COSMIC	2.642	Down-regulation
CMGC_CDK_CDK4_CDK4_ST	P15923	TCF3	P11802	CDK4	S359	G362D	362	Missense	distal	3	no	8.056	8.045	EPSD	COSMIC	2.642	Down-regulation
CMGC_CDK_CDK4_CDK4_ST	P15923	TCF3	P11802	CDK4	S379	G373R	373	Missense	distal	-6	no	8.806	8.529	EPSD	COSMIC	2.642	Down-regulation
CMGC_CDK_CDK4_CDK4_ST	P15923	TCF3	P11802	CDK4	S379	G385S	385	Missense	distal	6	no	8.806	9.102	EPSD	COSMIC	2.642	Up-regulation
CMGC_CDK_CDK4_CDK4_ST	P15923	TCF3	P11802	CDK4	S379	G385R	385	Missense	distal	6	no	8.806	8.990	EPSD	COSMIC	2.642	Up-regulation
CMGC_CDK_CDK4_CDK4_ST	P15923	TCF3	P11802	CDK4	S391	E394Q	394	Missense	distal	3	no	2.909	2.840	EPSD	COSMIC	2.642	Down-regulation
CMGC_CDK_CDK4_CDK4_ST	P15923	TCF3	P11802	CDK4	S391	G385S	385	Missense	distal	-6	no	2.909	2.362	EPSD	COSMIC	2.642	Loss
CMGC_CDK_CDK4_CDK4_ST	P15923	TCF3	P11802	CDK4	S391	G385R	385	Missense	distal	-6	no	2.909	2.633	EPSD	COSMIC	2.642	Loss
CMGC_CDK_CDK4_CDK4_ST	P15923	TCF3	P11802	CDK4	S529	A523V	523	Missense	distal	-6	no	8.297	8.552	EPSD	COSMIC	2.642	Up-regulation
CMGC_CDK_CDK4_CDK4_ST	P15923	TCF3	P11802	CDK4	S529	P530R	530	Missense	proximal	1	no	8.297	1.510	EPSD	COSMIC;GDSC;CCLE	2.642	Loss
CMGC_CDK_CDK4_CDK4_ST	P15923	TCF3	P11802	CDK4	S529	R527Q	527	Missense	proximal	-2	no	8.297	8.238	EPSD	COSMIC;CCLE	2.642	Down-regulation
CMGC_CDK_CDK4_CDK4_ST	P15923	TCF3	P11802	CDK4	S529	E532K	532	Missense	distal	3	no	8.297	8.585	EPSD	COSMIC;GDSC;CCLE	2.642	Up-regulation
CMGC_CDK_CDK4_CDK4_ST	P15923	TCF3	P11802	CDK4	S529	R525G	525	Missense	distal	-4	no	8.297	8.298	EPSD	COSMIC	2.642	Up-regulation
CMGC_CDK_CDK4_CDK4_ST	P15923	TCF3	P11802	CDK4	S529	E534K	534	Missense	distal	5	no	8.297	8.290	EPSD	COSMIC	2.642	Down-regulation
CMGC_CDK_CDK4_CDK4_ST	Q9BQA1	WDR77	P11802	CDK4	S176	A174V	174	Missense	proximal	-2	no	7.834	7.706	EPSD	COSMIC	2.642	Down-regulation
CMGC_CDK_CDK4_CDK4_ST	Q9BQA1	WDR77	P11802	CDK4	S264	H266N	266	Missense	proximal	2	no	9.198	9.263	PhosphoSitePlus;EPSD	COSMIC	2.642	Up-regulation
CMGC_CDK_CDK4_CDK4_ST	Q9BQA1	WDR77	P11802	CDK4	S264	S267N	267	Missense	distal	3	no	9.198	8.751	PhosphoSitePlus;EPSD	COSMIC	2.642	Down-regulation
CMGC_CDK_CDK4_CDK4_ST	Q9BQA1	WDR77	P11802	CDK4	S264	L261M	261	Missense	distal	-3	no	9.198	9.174	PhosphoSitePlus;EPSD	COSMIC	2.642	Down-regulation
CMGC_CDK_CDK4_CDK4_ST	Q9BQA1	WDR77	P11802	CDK4	S306	P307L	307	Missense	proximal	1	no	8.018	0.438	EPSD;PhosphoSitePlus	COSMIC	2.642	Loss
CMGC_CDK_CDK4_CDK4_ST	P55072	VCP	P11802	CDK4	S276	G280D	280	Missense	distal	4	no	3.045	2.869	EPSD	COSMIC	2.642	Down-regulation
CMGC_CDK_CDK4_CDK4_ST	P55072	VCP	P11802	CDK4	S276	G271C	271	Missense	distal	-5	no	3.045	3.114	EPSD	COSMIC	2.642	Up-regulation
CMGC_CDK_CDK4_CDK4_ST	P55072	VCP	P11802	CDK4	S276	E273G	273	Missense	distal	-3	no	3.045	3.155	EPSD	COSMIC	2.642	Up-regulation
CMGC_CDK_CDK4_CDK4_ST	P55072	VCP	P11802	CDK4	T509	F506Y	506	Missense	distal	-3	no	8.516	8.504	EPSD;PhosphoSitePlus	COSMIC	2.642	Down-regulation
CMGC_CDK_CDK4_CDK4_ST	P55072	VCP	P11802	CDK4	S664	L661M	661	Missense	distal	-3	no	6.758	6.733	PhosphoSitePlus;EPSD	COSMIC;GDSC;CCLE	2.642	Down-regulation
CMGC_CDK_CDK4_CDK4_ST	P55072	VCP	P11802	CDK4	S664	A667V	667	Missense	distal	3	no	6.758	6.334	PhosphoSitePlus;EPSD	COSMIC	2.642	Down-regulation
CMGC_CDK_CDK4_CDK4_ST	P55072	VCP	P11802	CDK4	S664	S664F	664	Missense	central	0	yes	6.758	0.000	PhosphoSitePlus;EPSD	COSMIC	2.642	Loss
CMGC_CDK_CDK4_CDK4_ST	Q92830	KAT2A	P11802	CDK4	S415	G413R	413	Missense	proximal	-2	no	3.333	3.409	EPSD	COSMIC	2.642	Up-regulation
CMGC_CDK_CDK4_CDK4_ST	Q92830	KAT2A	P11802	CDK4	S415	D422Y	422	Missense	distal	7	no	3.333	3.338	EPSD	COSMIC	2.642	Up-regulation
CMGC_CDK_CDK4_CDK4_ST	P46527	CDKN1B	P11802	CDK4	S10	R5L	5	Missense	distal	-5	no	7.994	7.950	EPSD	COSMIC	2.642	Down-regulation
CMGC_CDK_CDK4_CDK4_ST	P46527	CDKN1B	P11802	CDK4	S10	E14K	14	Missense	distal	4	no	7.994	7.943	EPSD	COSMIC	2.642	Down-regulation
CMGC_CDK_CDK4_CDK4_ST	P46527	CDKN1B	P11802	CDK4	S10	M16T	16	Missense	distal	6	no	7.994	8.058	EPSD	COSMIC	2.642	Up-regulation
CMGC_CDK_CDK4_CDK4_ST	P46527	CDKN1B	P11802	CDK4	S10	N3D	3	Missense	distal	-7	no	7.994	7.847	EPSD	COSMIC	2.642	Down-regulation
CMGC_CDK_CDK4_CDK4_ST	P46527	CDKN1B	P11802	CDK4	S10	P11S	11	Missense	proximal	1	no	7.994	1.806	EPSD	COSMIC	2.642	Loss
CMGC_CDK_CDK4_CDK4_ST	P46527	CDKN1B	P11802	CDK4	S10	S12N	12	Missense	proximal	2	no	7.994	7.810	EPSD	COSMIC	2.642	Down-regulation
CMGC_CDK_CDK4_CDK4_ST	P46527	CDKN1B	P11802	CDK4	S10	D17E	17	Missense	distal	7	no	7.994	8.004	EPSD	COSMIC	2.642	Up-regulation
CMGC_CDK_CDK4_CDK4_ST	P46527	CDKN1B	P11802	CDK4	S178	V184L	184	Missense	distal	6	no	7.626	7.644	EPSD	COSMIC	2.642	Up-regulation
CMGC_CDK_CDK4_CDK4_ST	P46527	CDKN1B	P11802	CDK4	S178	G182D	182	Missense	distal	4	no	7.626	7.450	EPSD	COSMIC	2.642	Down-regulation
CMGC_CDK_CDK4_CDK4_ST	P46527	CDKN1B	P11802	CDK4	T187	V184L	184	Missense	distal	-3	no	6.369	6.375	EPSD	COSMIC	2.642	Up-regulation
CMGC_CDK_CDK4_CDK4_ST	P46527	CDKN1B	P11802	CDK4	T187	G182D	182	Missense	distal	-5	no	6.369	6.470	EPSD	COSMIC	2.642	Up-regulation
CMGC_CDK_CDK4_CDK4_ST	P46527	CDKN1B	P11802	CDK4	T187	R194K	194	Missense	distal	7	no	6.369	6.371	EPSD	COSMIC	2.642	Up-regulation
CMGC_CDK_CDK4_CDK4_ST	P21333	FLNA	P11802	CDK4	S204	C210R	210	Missense	distal	6	no	2.917	3.023	EPSD	COSMIC	2.642	Up-regulation
CMGC_CDK_CDK4_CDK4_ST	P21333	FLNA	P11802	CDK4	S368	A361T	361	Missense	distal	-7	no	8.926	8.732	EPSD	COSMIC	2.642	Down-regulation
CMGC_CDK_CDK4_CDK4_ST	P21333	FLNA	P11802	CDK4	S368	V372L	372	Missense	distal	4	no	8.926	8.904	EPSD	COSMIC	2.642	Down-regulation
CMGC_CDK_CDK4_CDK4_ST	P21333	FLNA	P11802	CDK4	S468	Y470C	470	Missense	proximal	2	no	8.346	8.269	EPSD	COSMIC	2.642	Down-regulation
CMGC_CDK_CDK4_CDK4_ST	P21333	FLNA	P11802	CDK4	S468	G462D	462	Missense	distal	-6	no	8.346	8.133	EPSD	COSMIC	2.642	Down-regulation
CMGC_CDK_CDK4_CDK4_ST	P21333	FLNA	P11802	CDK4	S512	A510T	510	Missense	proximal	-2	no	2.809	2.787	EPSD	COSMIC	2.642	Down-regulation
CMGC_CDK_CDK4_CDK4_ST	P21333	FLNA	P11802	CDK4	S512	E514K	514	Missense	proximal	2	no	2.809	2.893	EPSD	COSMIC	2.642	Up-regulation
CMGC_CDK_CDK4_CDK4_ST	P21333	FLNA	P11802	CDK4	S512	G509S	509	Missense	distal	-3	no	2.809	2.586	EPSD	COSMIC	2.642	Loss
CMGC_CDK_CDK4_CDK4_ST	P21333	FLNA	P11802	CDK4	S512	E514G	514	Missense	proximal	2	no	2.809	2.565	EPSD	COSMIC	2.642	Loss
CMGC_CDK_CDK4_CDK4_ST	P21333	FLNA	P11802	CDK4	S512	V519A	519	Missense	distal	7	no	2.809	2.824	EPSD	COSMIC	2.642	Up-regulation
CMGC_CDK_CDK4_CDK4_ST	P21333	FLNA	P11802	CDK4	S564	R563C	563	Missense	proximal	-1	no	7.395	7.590	EPSD	COSMIC;GDSC;CCLE	2.642	Up-regulation
CMGC_CDK_CDK4_CDK4_ST	P21333	FLNA	P11802	CDK4	S564	E567G	567	Missense	distal	3	no	7.395	7.113	EPSD	COSMIC	2.642	Down-regulation
CMGC_CDK_CDK4_CDK4_ST	P21333	FLNA	P11802	CDK4	S564	R563H	563	Missense	proximal	-1	no	7.395	7.544	EPSD	COSMIC	2.642	Up-regulation
CMGC_CDK_CDK4_CDK4_ST	P21333	FLNA	P11802	CDK4	S564	S564C	564	Missense	central	0	yes	7.395	0.000	EPSD	COSMIC	2.642	Loss
CMGC_CDK_CDK4_CDK4_ST	P21333	FLNA	P11802	CDK4	S564	G562R	562	Missense	proximal	-2	no	7.395	7.471	EPSD	COSMIC	2.642	Up-regulation
CMGC_CDK_CDK4_CDK4_ST	P21333	FLNA	P11802	CDK4	S564	G562S	562	Missense	proximal	-2	no	7.395	7.587	EPSD	COSMIC	2.642	Up-regulation
CMGC_CDK_CDK4_CDK4_ST	P21333	FLNA	P11802	CDK4	S657	M660I	660	Missense	distal	3	no	7.746	7.585	EPSD	COSMIC	2.642	Down-regulation
CMGC_CDK_CDK4_CDK4_ST	P21333	FLNA	P11802	CDK4	S757	V752A	752	Missense	distal	-5	no	8.237	8.344	EPSD	COSMIC	2.642	Up-regulation
CMGC_CDK_CDK4_CDK4_ST	P21333	FLNA	P11802	CDK4	S757	V752I	752	Missense	distal	-5	no	8.237	8.243	EPSD	COSMIC	2.642	Up-regulation
CMGC_CDK_CDK4_CDK4_ST	P21333	FLNA	P11802	CDK4	S757	G751V	751	Missense	distal	-6	no	8.237	8.046	EPSD	COSMIC	2.642	Down-regulation
CMGC_CDK_CDK4_CDK4_ST	P21333	FLNA	P11802	CDK4	T857	S860N	860	Missense	distal	3	no	6.955	6.508	EPSD	COSMIC	2.642	Down-regulation
CMGC_CDK_CDK4_CDK4_ST	P21333	FLNA	P11802	CDK4	S860	S860N	860	Missense	central	0	yes	8.518	0.000	EPSD	COSMIC	2.642	Loss
CMGC_CDK_CDK4_CDK4_ST	P21333	FLNA	P11802	CDK4	T938	T938M	938	Missense	central	0	yes	6.102	0.000	EPSD	COSMIC	2.642	Loss
CMGC_CDK_CDK4_CDK4_ST	P21333	FLNA	P11802	CDK4	T938	Y933H	933	Missense	distal	-5	no	6.102	6.091	EPSD	COSMIC;CCLE	2.642	Down-regulation
CMGC_CDK_CDK4_CDK4_ST	P21333	FLNA	P11802	CDK4	S959	S959R	959	Missense	central	0	yes	8.279	0.000	EPSD	COSMIC	2.642	Loss
CMGC_CDK_CDK4_CDK4_ST	P21333	FLNA	P11802	CDK4	S966	S959R	959	Missense	distal	-7	no	9.227	8.740	EPSD	COSMIC	2.642	Down-regulation
CMGC_CDK_CDK4_CDK4_ST	P21333	FLNA	P11802	CDK4	S977	K975N	975	Missense	proximal	-2	no	2.811	2.781	EPSD	COSMIC;GDSC;CCLE	2.642	Down-regulation
CMGC_CDK_CDK4_CDK4_ST	P21333	FLNA	P11802	CDK4	S1055	G1054A	1054	Missense	proximal	-1	no	9.441	9.002	EPSD	COSMIC	2.642	Down-regulation
CMGC_CDK_CDK4_CDK4_ST	P21333	FLNA	P11802	CDK4	S1055	P1058S	1058	Missense	distal	3	no	9.441	9.136	EPSD	COSMIC	2.642	Down-regulation
CMGC_CDK_CDK4_CDK4_ST	P21333	FLNA	P11802	CDK4	S1084	A1086T	1086	Missense	proximal	2	no	7.951	7.861	EPSD	COSMIC;CCLE	2.642	Down-regulation
CMGC_CDK_CDK4_CDK4_ST	P21333	FLNA	P11802	CDK4	S1084	R1087C	1087	Missense	distal	3	no	7.951	7.511	EPSD	COSMIC;GDSC	2.642	Down-regulation
CMGC_CDK_CDK4_CDK4_ST	P21333	FLNA	P11802	CDK4	T1322	Y1324C	1324	Missense	proximal	2	no	6.321	6.244	EPSD	COSMIC	2.642	Down-regulation
CMGC_CDK_CDK4_CDK4_ST	P21333	FLNA	P11802	CDK4	T1322	M1316T	1316	Missense	distal	-6	no	6.321	6.189	EPSD	COSMIC;GDSC;CCLE	2.642	Down-regulation
CMGC_CDK_CDK4_CDK4_ST	P21333	FLNA	P11802	CDK4	S1436	P1441S	1441	Missense	distal	5	no	8.728	8.742	EPSD	COSMIC	2.642	Up-regulation
CMGC_CDK_CDK4_CDK4_ST	P21333	FLNA	P11802	CDK4	S1459	S1459R	1459	Missense	central	0	yes	7.700	0.000	EPSD;PhosphoSitePlus	COSMIC	2.642	Loss
CMGC_CDK_CDK4_CDK4_ST	P21333	FLNA	P11802	CDK4	S1459	G1457S	1457	Missense	proximal	-2	no	7.700	7.892	EPSD;PhosphoSitePlus	COSMIC	2.642	Up-regulation
CMGC_CDK_CDK4_CDK4_ST	P21333	FLNA	P11802	CDK4	S1533	V1539M	1539	Missense	distal	6	no	8.319	8.331	EPSD	COSMIC	2.642	Up-regulation
CMGC_CDK_CDK4_CDK4_ST	P21333	FLNA	P11802	CDK4	S1533	V1539A	1539	Missense	distal	6	no	8.319	8.439	EPSD	COSMIC	2.642	Up-regulation
CMGC_CDK_CDK4_CDK4_ST	P21333	FLNA	P11802	CDK4	S1734	P1732T	1732	Missense	proximal	-2	no	8.294	7.872	EPSD	COSMIC	2.642	Down-regulation
CMGC_CDK_CDK4_CDK4_ST	P21333	FLNA	P11802	CDK4	S1734	P1732S	1732	Missense	proximal	-2	no	8.294	7.989	EPSD	COSMIC	2.642	Down-regulation
CMGC_CDK_CDK4_CDK4_ST	P21333	FLNA	P11802	CDK4	S1854	P1852Q	1852	Missense	proximal	-2	no	8.438	7.958	EPSD	COSMIC	2.642	Down-regulation
CMGC_CDK_CDK4_CDK4_ST	P21333	FLNA	P11802	CDK4	S1854	S1854R	1854	Missense	central	0	yes	8.438	0.000	EPSD	COSMIC	2.642	Loss
CMGC_CDK_CDK4_CDK4_ST	P21333	FLNA	P11802	CDK4	S1906	C1912F	1912	Missense	distal	6	no	3.069	3.061	EPSD	COSMIC	2.642	Down-regulation
CMGC_CDK_CDK4_CDK4_ST	P21333	FLNA	P11802	CDK4	S1906	S1906R	1906	Missense	central	0	yes	3.069	0.000	EPSD	COSMIC	2.642	Loss
CMGC_CDK_CDK4_CDK4_ST	P21333	FLNA	P11802	CDK4	S1946	R1951H	1951	Missense	distal	5	no	8.552	8.561	EPSD	COSMIC	2.642	Up-regulation
CMGC_CDK_CDK4_CDK4_ST	P21333	FLNA	P11802	CDK4	S1946	A1950S	1950	Missense	distal	4	no	8.552	8.459	EPSD	COSMIC	2.642	Down-regulation
CMGC_CDK_CDK4_CDK4_ST	P21333	FLNA	P11802	CDK4	S1946	G1945C	1945	Missense	proximal	-1	no	8.552	8.375	EPSD	COSMIC	2.642	Down-regulation
CMGC_CDK_CDK4_CDK4_ST	P21333	FLNA	P11802	CDK4	S1946	R1951W	1951	Missense	distal	5	no	8.552	8.569	EPSD	COSMIC	2.642	Up-regulation
CMGC_CDK_CDK4_CDK4_ST	P21333	FLNA	P11802	CDK4	S1961	A1968P	1968	Missense	distal	7	no	2.732	2.733	EPSD	COSMIC	2.642	Up-regulation
CMGC_CDK_CDK4_CDK4_ST	P21333	FLNA	P11802	CDK4	S1961	S1961F	1961	Missense	central	0	yes	2.732	0.000	EPSD	COSMIC	2.642	Loss
CMGC_CDK_CDK4_CDK4_ST	P21333	FLNA	P11802	CDK4	S1967	A1968P	1968	Missense	proximal	1	no	0.586	7.524	EPSD	COSMIC	2.642	Gain
CMGC_CDK_CDK4_CDK4_ST	P21333	FLNA	P11802	CDK4	S2033	G2027A	2027	Missense	distal	-6	no	10.465	10.019	EPSD	COSMIC	2.642	Down-regulation
CMGC_CDK_CDK4_CDK4_ST	P21333	FLNA	P11802	CDK4	S2033	P2036Q	2036	Missense	distal	3	no	10.465	9.571	EPSD	COSMIC	2.642	Down-regulation
CMGC_CDK_CDK4_CDK4_ST	P21333	FLNA	P11802	CDK4	S2033	A2031V	2031	Missense	proximal	-2	no	10.465	10.338	EPSD	COSMIC	2.642	Down-regulation
CMGC_CDK_CDK4_CDK4_ST	P21333	FLNA	P11802	CDK4	S2033	S2040R	2040	Missense	distal	7	no	10.465	10.451	EPSD	COSMIC	2.642	Down-regulation
CMGC_CDK_CDK4_CDK4_ST	P21333	FLNA	P11802	CDK4	S2033	S2040L	2040	Missense	distal	7	no	10.465	10.440	EPSD	COSMIC	2.642	Down-regulation
CMGC_CDK_CDK4_CDK4_ST	P21333	FLNA	P11802	CDK4	S2033	G2027V	2027	Missense	distal	-6	no	10.465	10.274	EPSD	COSMIC	2.642	Down-regulation
CMGC_CDK_CDK4_CDK4_ST	P21333	FLNA	P11802	CDK4	S2128	F2130L	2130	Missense	proximal	2	no	9.970	10.044	EPSD	COSMIC	2.642	Up-regulation
CMGC_CDK_CDK4_CDK4_ST	P21333	FLNA	P11802	CDK4	S2128	D2122N	2122	Missense	distal	-6	no	9.970	9.849	EPSD	COSMIC	2.642	Down-regulation
CMGC_CDK_CDK4_CDK4_ST	P21333	FLNA	P11802	CDK4	S2180	G2183A	2183	Missense	distal	3	no	7.171	7.646	EPSD	COSMIC	2.642	Up-regulation
CMGC_CDK_CDK4_CDK4_ST	P21333	FLNA	P11802	CDK4	S2180	S2182L	2182	Missense	proximal	2	no	7.171	6.944	EPSD	COSMIC	2.642	Down-regulation
CMGC_CDK_CDK4_CDK4_ST	P21333	FLNA	P11802	CDK4	S2180	K2184R	2184	Missense	distal	4	no	7.171	7.226	EPSD	COSMIC	2.642	Up-regulation
CMGC_CDK_CDK4_CDK4_ST	P21333	FLNA	P11802	CDK4	S2224	G2218D	2218	Missense	distal	-6	no	9.496	9.283	EPSD	COSMIC;GDSC;CCLE	2.642	Down-regulation
CMGC_CDK_CDK4_CDK4_ST	P21333	FLNA	P11802	CDK4	S2224	G2223W	2223	Missense	proximal	-1	no	9.496	9.317	EPSD	COSMIC	2.642	Down-regulation
CMGC_CDK_CDK4_CDK4_ST	P21333	FLNA	P11802	CDK4	S2319	P2320T	2320	Missense	proximal	1	no	8.717	2.190	EPSD	COSMIC	2.642	Loss
CMGC_CDK_CDK4_CDK4_ST	P21333	FLNA	P11802	CDK4	S2327	P2320T	2320	Missense	distal	-7	no	6.517	6.307	EPSD	COSMIC	2.642	Down-regulation
CMGC_CDK_CDK4_CDK4_ST	P21333	FLNA	P11802	CDK4	S2343	V2337F	2337	Missense	distal	-6	no	3.429	3.441	EPSD	COSMIC	2.642	Up-regulation
CMGC_CDK_CDK4_CDK4_ST	P21333	FLNA	P11802	CDK4	S2343	G2344W	2344	Missense	proximal	1	no	3.429	2.401	EPSD	COSMIC	2.642	Loss
CMGC_CDK_CDK4_CDK4_ST	P21333	FLNA	P11802	CDK4	S2343	V2337I	2337	Missense	distal	-6	no	3.429	3.441	EPSD	COSMIC	2.642	Up-regulation
CMGC_CDK_CDK4_CDK4_ST	P21333	FLNA	P11802	CDK4	S2343	S2343N	2343	Missense	central	0	yes	3.429	0.000	EPSD	COSMIC	2.642	Loss
CMGC_CDK_CDK4_CDK4_ST	P21333	FLNA	P11802	CDK4	S2352	F2353C	2353	Missense	proximal	1	no	3.806	2.588	EPSD	COSMIC	2.642	Loss
CMGC_CDK_CDK4_CDK4_ST	P21333	FLNA	P11802	CDK4	S2370	D2365N	2365	Missense	distal	-5	no	8.154	8.187	EPSD	COSMIC	2.642	Up-regulation
CMGC_CDK_CDK4_CDK4_ST	P21333	FLNA	P11802	CDK4	S2370	S2370N	2370	Missense	central	0	yes	8.154	0.000	EPSD	COSMIC	2.642	Loss
CMGC_CDK_CDK4_CDK4_ST	P21333	FLNA	P11802	CDK4	S2414	P2415R	2415	Missense	proximal	1	no	10.927	4.140	EPSD	COSMIC	2.642	Down-regulation
CMGC_CDK_CDK4_CDK4_ST	P21333	FLNA	P11802	CDK4	S2414	V2420F	2420	Missense	distal	6	no	10.927	10.900	EPSD	COSMIC	2.642	Down-regulation
CMGC_CDK_CDK4_CDK4_ST	P21333	FLNA	P11802	CDK4	S2414	G2408S	2408	Missense	distal	-6	no	10.927	10.380	EPSD	COSMIC	2.642	Down-regulation
CMGC_CDK_CDK4_CDK4_ST	P21333	FLNA	P11802	CDK4	S2414	G2413E	2413	Missense	proximal	-1	no	10.927	10.600	EPSD	COSMIC	2.642	Down-regulation
CMGC_CDK_CDK4_CDK4_ST	P21333	FLNA	P11802	CDK4	T2488	R2484C	2484	Missense	distal	-4	no	6.404	6.405	EPSD	COSMIC	2.642	Up-regulation
CMGC_CDK_CDK4_CDK4_ST	P21333	FLNA	P11802	CDK4	T2488	E2481D	2481	Missense	distal	-7	no	6.404	6.174	EPSD	COSMIC	2.642	Down-regulation
CMGC_CDK_CDK4_CDK4_ST	P21333	FLNA	P11802	CDK4	T2488	Y2483C	2483	Missense	distal	-5	no	6.404	6.367	EPSD	COSMIC	2.642	Down-regulation
CMGC_CDK_CDK4_CDK4_ST	P21333	FLNA	P11802	CDK4	S2510	P2504S	2504	Missense	distal	-6	no	6.664	6.454	EPSD	COSMIC	2.642	Down-regulation
CMGC_CDK_CDK4_CDK4_ST	P21333	FLNA	P11802	CDK4	S2510	P2511L	2511	Missense	proximal	1	no	6.664	-0.916	EPSD	COSMIC	2.642	Loss
CMGC_CDK_CDK4_CDK4_ST	P21333	FLNA	P11802	CDK4	S2510	S2510F	2510	Missense	central	0	yes	6.664	0.000	EPSD	COSMIC	2.642	Loss
CMGC_CDK_CDK4_CDK4_ST	P21333	FLNA	P11802	CDK4	T2542	C2543F	2543	Missense	proximal	1	no	1.510	2.727	EPSD	COSMIC	2.642	Gain
CMGC_CDK_CDK4_CDK4_ST	P21333	FLNA	P11802	CDK4	T2599	G2596S	2596	Missense	distal	-3	no	7.664	7.441	EPSD	COSMIC	2.642	Down-regulation
CMGC_CDK_CDK4_CDK4_ST	P21333	FLNA	P11802	CDK4	T2599	G2593V	2593	Missense	distal	-6	no	7.664	7.473	EPSD	COSMIC	2.642	Down-regulation
CMGC_CDK_CDK4_CDK4_ST	P21333	FLNA	P11802	CDK4	S2640	P2641L	2641	Missense	proximal	1	no	8.982	1.403	EPSD	COSMIC	2.642	Loss
CMGC_CDK_CDK4_CDK4_ST	P21333	FLNA	P11802	CDK4	S2640	R2643C	2643	Missense	distal	3	no	8.982	8.541	EPSD	COSMIC	2.642	Down-regulation
CMGC_CDK_CDK4_CDK4_ST	P04179	SOD2	P11802	CDK4	S106	L105R	105	Missense	proximal	-1	no	7.812	7.672	PhosphoSitePlus	COSMIC	2.642	Down-regulation
CMGC_CDK_CDK4_CDK4_ST	P04179	SOD2	P11802	CDK4	S106	G109C	109	Missense	distal	3	no	7.812	7.933	PhosphoSitePlus	COSMIC	2.642	Up-regulation
CMGC_CDK_CDK4_CDK4_ST	P04179	SOD2	P11802	CDK4	S127	F131L	131	Missense	distal	4	no	4.127	4.097	EPSD	COSMIC	2.642	Down-regulation
CMGC_CDK_CDK4_CDK4_ST	P04179	SOD2	P11802	CDK4	S127	R123C	123	Missense	distal	-4	no	4.127	4.128	EPSD	COSMIC	2.642	Up-regulation
CMGC_CDK_CDK4_CDK4_ST	P04179	SOD2	P11802	CDK4	S127	K134T	134	Missense	distal	7	no	4.127	4.124	EPSD	COSMIC	2.642	Down-regulation
CMGC_CDK_CDK4_CDK4_ST	O15151	MDM4	P11802	CDK4	S20	S20C	20	Missense	central	0	yes	8.538	0.000	EPSD	COSMIC	2.642	Loss
CMGC_CDK_CDK4_CDK4_ST	O15151	MDM4	P11802	CDK4	S20	S15R	15	Missense	distal	-5	no	8.538	8.430	EPSD	COSMIC	2.642	Down-regulation
CMGC_CDK_CDK4_CDK4_ST	O15151	MDM4	P11802	CDK4	S20	I24M	24	Missense	distal	4	no	8.538	8.492	EPSD	COSMIC	2.642	Down-regulation
CMGC_CDK_CDK4_CDK4_ST	O15151	MDM4	P11802	CDK4	S20	P21S	21	Missense	proximal	1	no	8.538	2.351	EPSD	COSMIC	2.642	Loss
CMGC_CDK_CDK4_CDK4_ST	O15151	MDM4	P11802	CDK4	S20	D14H	14	Missense	distal	-6	no	8.538	8.518	EPSD	COSMIC	2.642	Down-regulation
CMGC_CDK_CDK4_CDK4_ST	O15151	MDM4	P11802	CDK4	S314	E308D	308	Missense	distal	-6	no	8.711	8.836	PhosphoSitePlus	COSMIC	2.642	Up-regulation
CMGC_CDK_CDK4_CDK4_ST	Q13761	RUNX3	P11802	CDK4	T14	S17F	17	Missense	distal	3	no	7.004	6.413	EPSD	COSMIC	2.642	Down-regulation
CMGC_CDK_CDK4_CDK4_ST	Q13761	RUNX3	P11802	CDK4	S17	S17F	17	Missense	central	0	yes	7.748	0.000	EPSD	COSMIC	2.642	Loss
CMGC_CDK_CDK4_CDK4_ST	Q13761	RUNX3	P11802	CDK4	S71	D70N	70	Missense	proximal	-1	no	7.041	6.918	EPSD	COSMIC	2.642	Down-regulation
CMGC_CDK_CDK4_CDK4_ST	Q13761	RUNX3	P11802	CDK4	S71	R68C	68	Missense	distal	-3	no	7.041	7.110	EPSD	COSMIC	2.642	Up-regulation
CMGC_CDK_CDK4_CDK4_ST	Q13761	RUNX3	P11802	CDK4	S71	R68H	68	Missense	distal	-3	no	7.041	7.084	EPSD	COSMIC	2.642	Up-regulation
CMGC_CDK_CDK4_CDK4_ST	Q13761	RUNX3	P11802	CDK4	S71	C76F	76	Missense	distal	5	no	7.041	7.034	EPSD	COSMIC	2.642	Down-regulation
CMGC_CDK_CDK4_CDK4_ST	Q13761	RUNX3	P11802	CDK4	S71	N73Y	73	Missense	proximal	2	no	7.041	7.005	EPSD	COSMIC	2.642	Down-regulation
CMGC_CDK_CDK4_CDK4_ST	Q13761	RUNX3	P11802	CDK4	S71	E65G	65	Missense	distal	-6	no	7.041	7.378	EPSD	COSMIC	2.642	Up-regulation
CMGC_CDK_CDK4_CDK4_ST	Q13761	RUNX3	P11802	CDK4	S149	K148N	148	Missense	proximal	-1	no	2.636	2.737	EPSD	COSMIC	2.642	Gain
CMGC_CDK_CDK4_CDK4_ST	Q13761	RUNX3	P11802	CDK4	S149	R143L	143	Missense	distal	-6	no	2.636	2.728	EPSD	COSMIC	2.642	Gain
CMGC_CDK_CDK4_CDK4_ST	Q13761	RUNX3	P11802	CDK4	S149	R143H	143	Missense	distal	-6	no	2.636	2.680	EPSD	COSMIC	2.642	Gain
CMGC_CDK_CDK4_CDK4_ST	Q13761	RUNX3	P11802	CDK4	S149	R143C	143	Missense	distal	-6	no	2.636	2.741	EPSD	COSMIC	2.642	Gain
CMGC_CDK_CDK4_CDK4_ST	Q13761	RUNX3	P11802	CDK4	T209	P210L	210	Missense	proximal	1	no	7.556	-0.023	EPSD	COSMIC	2.642	Loss
CMGC_CDK_CDK4_CDK4_ST	Q13761	RUNX3	P11802	CDK4	T209	V208G	208	Missense	proximal	-1	no	7.556	7.758	EPSD	COSMIC	2.642	Up-regulation
CMGC_CDK_CDK4_CDK4_ST	Q13761	RUNX3	P11802	CDK4	T209	R216Q	216	Missense	distal	7	no	7.556	7.551	EPSD	COSMIC	2.642	Down-regulation
CMGC_CDK_CDK4_CDK4_ST	Q13761	RUNX3	P11802	CDK4	T209	R203L	203	Missense	distal	-6	no	7.556	7.648	EPSD	COSMIC	2.642	Up-regulation
CMGC_CDK_CDK4_CDK4_ST	Q13761	RUNX3	P11802	CDK4	T209	S214G	214	Missense	distal	5	no	7.556	7.603	EPSD	COSMIC	2.642	Up-regulation
CMGC_CDK_CDK4_CDK4_ST	Q13761	RUNX3	P11802	CDK4	T209	P215L	215	Missense	distal	6	no	7.556	7.534	EPSD	COSMIC	2.642	Down-regulation
CMGC_CDK_CDK4_CDK4_ST	Q13761	RUNX3	P11802	CDK4	T212	R205C	205	Missense	distal	-7	no	9.097	8.833	EPSD	COSMIC	2.642	Down-regulation
CMGC_CDK_CDK4_CDK4_ST	Q13761	RUNX3	P11802	CDK4	T212	P210L	210	Missense	proximal	-2	no	9.097	8.568	EPSD	COSMIC	2.642	Down-regulation
CMGC_CDK_CDK4_CDK4_ST	Q13761	RUNX3	P11802	CDK4	T212	R216Q	216	Missense	distal	4	no	9.097	9.163	EPSD	COSMIC	2.642	Up-regulation
CMGC_CDK_CDK4_CDK4_ST	Q13761	RUNX3	P11802	CDK4	T212	S214G	214	Missense	proximal	2	no	9.097	8.663	EPSD	COSMIC	2.642	Down-regulation
CMGC_CDK_CDK4_CDK4_ST	Q13761	RUNX3	P11802	CDK4	T212	P215L	215	Missense	distal	3	no	9.097	8.198	EPSD	COSMIC	2.642	Down-regulation
CMGC_CDK_CDK4_CDK4_ST	Q13761	RUNX3	P11802	CDK4	T212	R205H	205	Missense	distal	-7	no	9.097	8.949	EPSD	COSMIC	2.642	Down-regulation
CMGC_CDK_CDK4_CDK4_ST	Q13761	RUNX3	P11802	CDK4	S214	P210L	210	Missense	distal	-4	no	7.185	7.187	EPSD	COSMIC	2.642	Up-regulation
CMGC_CDK_CDK4_CDK4_ST	Q13761	RUNX3	P11802	CDK4	S214	S220G	220	Missense	distal	6	no	7.185	6.890	EPSD	COSMIC	2.642	Down-regulation
CMGC_CDK_CDK4_CDK4_ST	Q13761	RUNX3	P11802	CDK4	S214	V208G	208	Missense	distal	-6	no	7.185	7.377	EPSD	COSMIC	2.642	Up-regulation
CMGC_CDK_CDK4_CDK4_ST	Q13761	RUNX3	P11802	CDK4	S214	R216Q	216	Missense	proximal	2	no	7.185	7.077	EPSD	COSMIC	2.642	Down-regulation
CMGC_CDK_CDK4_CDK4_ST	Q13761	RUNX3	P11802	CDK4	S214	S214G	214	Missense	central	0	yes	7.185	0.000	EPSD	COSMIC	2.642	Loss
CMGC_CDK_CDK4_CDK4_ST	Q13761	RUNX3	P11802	CDK4	S214	S220N	220	Missense	distal	6	no	7.185	7.046	EPSD	COSMIC	2.642	Down-regulation
CMGC_CDK_CDK4_CDK4_ST	Q13761	RUNX3	P11802	CDK4	S214	P215L	215	Missense	proximal	1	no	7.185	-0.394	EPSD	COSMIC	2.642	Loss
CMGC_CDK_CDK4_CDK4_ST	Q13761	RUNX3	P11802	CDK4	T231	P229L	229	Missense	proximal	-2	no	6.894	6.365	EPSD	COSMIC	2.642	Down-regulation
CMGC_CDK_CDK4_CDK4_ST	Q13761	RUNX3	P11802	CDK4	T231	P232T	232	Missense	proximal	1	no	6.894	0.367	EPSD	COSMIC	2.642	Loss
CMGC_CDK_CDK4_CDK4_ST	Q13761	RUNX3	P11802	CDK4	T231	Q230K	230	Missense	proximal	-1	no	6.894	6.743	EPSD	COSMIC	2.642	Down-regulation
CMGC_CDK_CDK4_CDK4_ST	Q13761	RUNX3	P11802	CDK4	T231	P232Q	232	Missense	proximal	1	no	6.894	-0.275	EPSD	COSMIC	2.642	Loss
CMGC_CDK_CDK4_CDK4_ST	Q13761	RUNX3	P11802	CDK4	T231	P232S	232	Missense	proximal	1	no	6.894	0.707	EPSD	COSMIC	2.642	Loss
CMGC_CDK_CDK4_CDK4_ST	Q13761	RUNX3	P11802	CDK4	S243	D249N	249	Missense	distal	6	no	3.015	3.070	EPSD	COSMIC	2.642	Up-regulation
CMGC_CDK_CDK4_CDK4_ST	Q13761	RUNX3	P11802	CDK4	S243	Q247K	247	Missense	distal	4	no	3.015	2.894	EPSD	COSMIC	2.642	Down-regulation
CMGC_CDK_CDK4_CDK4_ST	Q13761	RUNX3	P11802	CDK4	S243	R246C	246	Missense	distal	3	no	3.015	2.575	EPSD	COSMIC	2.642	Loss
CMGC_CDK_CDK4_CDK4_ST	Q13761	RUNX3	P11802	CDK4	S243	P241L	241	Missense	proximal	-2	no	3.015	2.487	EPSD	COSMIC	2.642	Loss
CMGC_CDK_CDK4_CDK4_ST	Q13761	RUNX3	P11802	CDK4	S243	D244A	244	Missense	proximal	1	no	3.015	3.265	EPSD	COSMIC	2.642	Up-regulation
CMGC_CDK_CDK4_CDK4_ST	Q13761	RUNX3	P11802	CDK4	S243	R250C	250	Missense	distal	7	no	3.015	3.005	EPSD	COSMIC	2.642	Down-regulation
CMGC_CDK_CDK4_CDK4_ST	Q13761	RUNX3	P11802	CDK4	S243	F242L	242	Missense	proximal	-1	no	3.015	2.933	EPSD	COSMIC	2.642	Down-regulation
CMGC_CDK_CDK4_CDK4_ST	Q13761	RUNX3	P11802	CDK4	S251	D244A	244	Missense	distal	-7	no	2.369	2.767	EPSD	COSMIC	2.642	Gain
CMGC_CDK_CDK4_CDK4_ST	Q13761	RUNX3	P11802	CDK4	S261	D265E	265	Missense	distal	4	no	2.701	2.535	EPSD	COSMIC	2.642	Loss
CMGC_CDK_CDK4_CDK4_ST	Q13761	RUNX3	P11802	CDK4	S261	R267M	267	Missense	distal	6	no	2.701	2.626	EPSD	COSMIC	2.642	Loss
CMGC_CDK_CDK4_CDK4_ST	Q13761	RUNX3	P11802	CDK4	S261	E260K	260	Missense	proximal	-1	no	2.701	2.610	EPSD	COSMIC	2.642	Loss
CMGC_CDK_CDK4_CDK4_ST	Q13761	RUNX3	P11802	CDK4	S261	P264Q	264	Missense	distal	3	no	2.701	1.807	EPSD	COSMIC	2.642	Loss
CMGC_CDK_CDK4_CDK4_ST	Q13761	RUNX3	P11802	CDK4	S261	F263I	263	Missense	proximal	2	no	2.701	2.727	EPSD	COSMIC	2.642	Up-regulation
CMGC_CDK_CDK4_CDK4_ST	Q13761	RUNX3	P11802	CDK4	S261	P266T	266	Missense	distal	5	no	2.701	2.737	EPSD	COSMIC	2.642	Up-regulation
CMGC_CDK_CDK4_CDK4_ST	Q13761	RUNX3	P11802	CDK4	S261	T254M	254	Missense	distal	-7	no	2.701	2.487	EPSD	COSMIC	2.642	Loss
CMGC_CDK_CDK4_CDK4_ST	Q13761	RUNX3	P11802	CDK4	S261	T259M	259	Missense	proximal	-2	no	2.701	2.647	EPSD	COSMIC	2.642	Down-regulation
CMGC_CDK_CDK4_CDK4_ST	Q13761	RUNX3	P11802	CDK4	S261	R267G	267	Missense	distal	6	no	2.701	2.517	EPSD	COSMIC	2.642	Loss
CMGC_CDK_CDK4_CDK4_ST	Q13761	RUNX3	P11802	CDK4	S356	A362T	362	Missense	distal	6	no	8.240	8.196	PhosphoSitePlus	COSMIC	2.642	Down-regulation
CMGC_CDK_CDK4_CDK4_ST	Q13761	RUNX3	P11802	CDK4	S395	T399M	399	Missense	distal	4	no	3.292	3.409	EPSD	COSMIC	2.642	Up-regulation
CMGC_CDK_CDK4_CDK4_ST	Q13761	RUNX3	P11802	CDK4	S395	G392S	392	Missense	distal	-3	no	3.292	3.069	EPSD	COSMIC	2.642	Down-regulation
CMGC_CDK_CDK4_CDK4_ST	Q13761	RUNX3	P11802	CDK4	S397	T399M	399	Missense	proximal	2	no	7.175	7.114	EPSD	COSMIC	2.642	Down-regulation
CMGC_CDK_CDK4_CDK4_ST	Q13761	RUNX3	P11802	CDK4	S397	P404T	404	Missense	distal	7	no	7.175	7.167	EPSD	COSMIC	2.642	Down-regulation
CMGC_CDK_CDK4_CDK4_ST	Q13761	RUNX3	P11802	CDK4	S397	P404S	404	Missense	distal	7	no	7.175	7.183	EPSD	COSMIC	2.642	Up-regulation
CMGC_CDK_CDK4_CDK4_ST	Q13761	RUNX3	P11802	CDK4	S397	G392S	392	Missense	distal	-5	no	7.175	7.402	EPSD	COSMIC	2.642	Up-regulation
CMGC_CDK_CDK4_CDK4_ST	Q13761	RUNX3	P11802	CDK4	T403	P404T	404	Missense	proximal	1	no	6.059	-0.468	EPSD	COSMIC	2.642	Loss
CMGC_CDK_CDK4_CDK4_ST	Q13761	RUNX3	P11802	CDK4	T403	P404S	404	Missense	proximal	1	no	6.059	-0.129	EPSD	COSMIC	2.642	Loss
CMGC_CDK_CDK4_CDK4_ST	Q92879	CELF1	P11802	CDK4	S178	Q172H	172	Missense	distal	-6	no	2.636	2.675	EPSD	COSMIC	2.642	Gain
CMGC_CDK_CDK4_CDK4_ST	Q92879	CELF1	P11802	CDK4	S178	V182G	182	Missense	distal	4	no	2.636	2.814	EPSD	COSMIC	2.642	Gain
CMGC_CDK_CDK4_CDK4_ST	Q92879	CELF1	P11802	CDK4	S179	Q172H	172	Missense	distal	-7	no	6.729	6.640	EPSD	COSMIC	2.642	Down-regulation
CMGC_CDK_CDK4_CDK4_ST	Q92879	CELF1	P11802	CDK4	S179	P180H	180	Missense	proximal	1	no	6.729	0.146	EPSD	COSMIC	2.642	Loss
CMGC_CDK_CDK4_CDK4_ST	Q92879	CELF1	P11802	CDK4	S179	A186T	186	Missense	distal	7	no	6.729	6.723	EPSD	COSMIC	2.642	Down-regulation
CMGC_CDK_CDK4_CDK4_ST	Q92879	CELF1	P11802	CDK4	S179	V182G	182	Missense	distal	3	no	6.729	6.678	EPSD	COSMIC	2.642	Down-regulation
CMGC_CDK_CDK4_CDK4_ST	Q92879	CELF1	P11802	CDK4	S241	G242R	242	Missense	proximal	1	no	3.150	2.164	EPSD	COSMIC	2.642	Loss
CMGC_CDK_CDK4_CDK4_ST	Q92879	CELF1	P11802	CDK4	S241	L247R	247	Missense	distal	6	no	3.150	3.218	EPSD	COSMIC	2.642	Up-regulation
CMGC_CDK_CDK4_CDK4_ST	Q92879	CELF1	P11802	CDK4	S241	L247M	247	Missense	distal	6	no	3.150	3.143	EPSD	COSMIC	2.642	Down-regulation
CMGC_CDK_CDK4_CDK4_ST	Q92879	CELF1	P11802	CDK4	S241	N245S	245	Missense	distal	4	no	3.150	2.924	EPSD	COSMIC	2.642	Down-regulation
CMGC_CDK_CDK4_CDK4_ST	Q92879	CELF1	P11802	CDK4	S297	S299R	299	Missense	proximal	2	no	3.097	2.976	EPSD	COSMIC	2.642	Down-regulation
CMGC_CDK_CDK4_CDK4_ST	Q92879	CELF1	P11802	CDK4	S297	S297L	297	Missense	central	0	yes	3.097	0.000	EPSD	COSMIC	2.642	Loss
CMGC_CDK_CDK4_CDK4_ST	Q92879	CELF1	P11802	CDK4	S297	S302R	302	Missense	distal	5	no	3.097	3.120	EPSD	COSMIC	2.642	Up-regulation
CMGC_CDK_CDK4_CDK4_ST	Q92879	CELF1	P11802	CDK4	S297	S296L	296	Missense	proximal	-1	no	3.097	3.383	EPSD	COSMIC	2.642	Up-regulation
CMGC_CDK_CDK4_CDK4_ST	Q92879	CELF1	P11802	CDK4	S297	S304R	304	Missense	distal	7	no	3.097	3.083	EPSD	COSMIC	2.642	Down-regulation
CMGC_CDK_CDK4_CDK4_ST	Q92879	CELF1	P11802	CDK4	S297	P290R	290	Missense	distal	-7	no	3.097	2.810	EPSD	COSMIC	2.642	Down-regulation
CMGC_CDK_CDK4_CDK4_ST	Q92879	CELF1	P11802	CDK4	S297	S300L	300	Missense	distal	3	no	3.097	2.504	EPSD	COSMIC	2.642	Loss
CMGC_CDK_CDK4_CDK4_ST	Q92879	CELF1	P11802	CDK4	S297	P290L	290	Missense	distal	-7	no	3.097	2.618	EPSD	COSMIC	2.642	Loss
CMGC_CDK_CDK4_CDK4_ST	Q92879	CELF1	P11802	CDK4	S299	S305N	305	Missense	distal	6	no	2.705	2.566	EPSD	COSMIC	2.642	Loss
CMGC_CDK_CDK4_CDK4_ST	Q92879	CELF1	P11802	CDK4	S299	S299R	299	Missense	central	0	yes	2.705	0.000	EPSD	COSMIC	2.642	Loss
CMGC_CDK_CDK4_CDK4_ST	Q92879	CELF1	P11802	CDK4	S299	S297L	297	Missense	proximal	-2	no	2.705	2.481	EPSD	COSMIC	2.642	Loss
CMGC_CDK_CDK4_CDK4_ST	Q92879	CELF1	P11802	CDK4	S299	S302R	302	Missense	distal	3	no	2.705	2.463	EPSD	COSMIC	2.642	Loss
CMGC_CDK_CDK4_CDK4_ST	Q92879	CELF1	P11802	CDK4	S299	S296L	296	Missense	distal	-3	no	2.705	2.887	EPSD	COSMIC	2.642	Up-regulation
CMGC_CDK_CDK4_CDK4_ST	Q92879	CELF1	P11802	CDK4	S299	S306N	306	Missense	distal	7	no	2.705	2.690	EPSD	COSMIC	2.642	Down-regulation
CMGC_CDK_CDK4_CDK4_ST	Q92879	CELF1	P11802	CDK4	S299	S304R	304	Missense	distal	5	no	2.705	2.727	EPSD	COSMIC	2.642	Up-regulation
CMGC_CDK_CDK4_CDK4_ST	Q92879	CELF1	P11802	CDK4	S299	S305R	305	Missense	distal	6	no	2.705	2.594	EPSD	COSMIC	2.642	Loss
CMGC_CDK_CDK4_CDK4_ST	Q92879	CELF1	P11802	CDK4	S299	V293M	293	Missense	distal	-6	no	2.705	2.669	EPSD	COSMIC	2.642	Down-regulation
CMGC_CDK_CDK4_CDK4_ST	Q92879	CELF1	P11802	CDK4	S299	S300L	300	Missense	proximal	1	no	2.705	1.313	EPSD	COSMIC	2.642	Loss
CMGC_CDK_CDK4_CDK4_ST	Q92879	CELF1	P11802	CDK4	S300	S305N	305	Missense	distal	5	no	6.987	7.011	EPSD	COSMIC	2.642	Up-regulation
CMGC_CDK_CDK4_CDK4_ST	Q92879	CELF1	P11802	CDK4	S300	S299R	299	Missense	proximal	-1	no	6.987	7.132	EPSD	COSMIC	2.642	Up-regulation
CMGC_CDK_CDK4_CDK4_ST	Q92879	CELF1	P11802	CDK4	S300	S297L	297	Missense	distal	-3	no	6.987	7.170	EPSD	COSMIC	2.642	Up-regulation
CMGC_CDK_CDK4_CDK4_ST	Q92879	CELF1	P11802	CDK4	S300	S302R	302	Missense	proximal	2	no	6.987	6.865	EPSD	COSMIC	2.642	Down-regulation
CMGC_CDK_CDK4_CDK4_ST	Q92879	CELF1	P11802	CDK4	S300	S296L	296	Missense	distal	-4	no	6.987	6.988	EPSD	COSMIC	2.642	Up-regulation
CMGC_CDK_CDK4_CDK4_ST	Q92879	CELF1	P11802	CDK4	S300	S306N	306	Missense	distal	6	no	6.987	6.848	EPSD	COSMIC	2.642	Down-regulation
CMGC_CDK_CDK4_CDK4_ST	Q92879	CELF1	P11802	CDK4	S300	S304R	304	Missense	distal	4	no	6.987	7.218	EPSD	COSMIC	2.642	Up-regulation
CMGC_CDK_CDK4_CDK4_ST	Q92879	CELF1	P11802	CDK4	S300	S305R	305	Missense	distal	5	no	6.987	7.010	EPSD	COSMIC	2.642	Up-regulation
CMGC_CDK_CDK4_CDK4_ST	Q92879	CELF1	P11802	CDK4	S300	V293M	293	Missense	distal	-7	no	6.987	7.064	EPSD	COSMIC	2.642	Up-regulation
CMGC_CDK_CDK4_CDK4_ST	Q92879	CELF1	P11802	CDK4	S300	S300L	300	Missense	central	0	yes	6.987	0.000	EPSD	COSMIC	2.642	Loss
CMGC_CDK_CDK4_CDK4_ST	Q92879	CELF1	P11802	CDK4	S302	S305N	305	Missense	distal	3	no	4.128	3.681	PhosphoSitePlus	COSMIC	2.642	Down-regulation
CMGC_CDK_CDK4_CDK4_ST	Q92879	CELF1	P11802	CDK4	S302	S299R	299	Missense	distal	-3	no	4.128	4.232	PhosphoSitePlus	COSMIC	2.642	Up-regulation
CMGC_CDK_CDK4_CDK4_ST	Q92879	CELF1	P11802	CDK4	S302	S297L	297	Missense	distal	-5	no	4.128	3.976	PhosphoSitePlus	COSMIC	2.642	Down-regulation
CMGC_CDK_CDK4_CDK4_ST	Q92879	CELF1	P11802	CDK4	S302	S302R	302	Missense	central	0	yes	4.128	0.000	PhosphoSitePlus	COSMIC	2.642	Loss
CMGC_CDK_CDK4_CDK4_ST	Q92879	CELF1	P11802	CDK4	S302	S296L	296	Missense	distal	-6	no	4.128	4.491	PhosphoSitePlus	COSMIC	2.642	Up-regulation
CMGC_CDK_CDK4_CDK4_ST	Q92879	CELF1	P11802	CDK4	S302	S306N	306	Missense	distal	4	no	4.128	4.354	PhosphoSitePlus	COSMIC	2.642	Up-regulation
CMGC_CDK_CDK4_CDK4_ST	Q92879	CELF1	P11802	CDK4	S302	S304R	304	Missense	proximal	2	no	4.128	4.006	PhosphoSitePlus	COSMIC	2.642	Down-regulation
CMGC_CDK_CDK4_CDK4_ST	Q92879	CELF1	P11802	CDK4	S302	S305R	305	Missense	distal	3	no	4.128	3.886	PhosphoSitePlus	COSMIC	2.642	Down-regulation
CMGC_CDK_CDK4_CDK4_ST	Q92879	CELF1	P11802	CDK4	S302	S300L	300	Missense	proximal	-2	no	4.128	3.905	PhosphoSitePlus	COSMIC	2.642	Down-regulation
CMGC_CDK_CDK4_CDK4_ST	Q92879	CELF1	P11802	CDK4	S306	S300L	300	Missense	distal	-6	no	2.411	2.774	EPSD	COSMIC	2.642	Gain
CMGC_CDK_CDK4_CDK4_ST	P04637	TP53	P11802	CDK4	S9	V10G	10	Missense	proximal	1	no	1.291	2.818	EPSD	COSMIC	2.642	Gain
CMGC_CDK_CDK4_CDK4_ST	P04637	TP53	P11802	CDK4	S33	M40I	40	Missense	distal	7	no	7.064	7.061	EPSD	COSMIC	2.642	Down-regulation
CMGC_CDK_CDK4_CDK4_ST	P04637	TP53	P11802	CDK4	S33	V31I	31	Missense	proximal	-2	no	7.064	7.058	EPSD	COSMIC;GDSC;CCLE	2.642	Down-regulation
CMGC_CDK_CDK4_CDK4_ST	P04637	TP53	P11802	CDK4	S33	P36L	36	Missense	distal	3	no	7.064	6.166	EPSD	COSMIC;GDSC;CCLE	2.642	Down-regulation
CMGC_CDK_CDK4_CDK4_ST	P04637	TP53	P11802	CDK4	S33	L35F	35	Missense	proximal	2	no	7.064	6.991	EPSD	COSMIC	2.642	Down-regulation
CMGC_CDK_CDK4_CDK4_ST	P04637	TP53	P11802	CDK4	S33	Q38L	38	Missense	distal	5	no	7.064	7.070	EPSD	COSMIC	2.642	Up-regulation
CMGC_CDK_CDK4_CDK4_ST	P04637	TP53	P11802	CDK4	S33	S37T	37	Missense	distal	4	no	7.064	7.291	EPSD	COSMIC	2.642	Up-regulation
CMGC_CDK_CDK4_CDK4_ST	P04637	TP53	P11802	CDK4	S33	L26P	26	Missense	distal	-7	no	7.064	7.544	EPSD	COSMIC	2.642	Up-regulation
CMGC_CDK_CDK4_CDK4_ST	P04637	TP53	P11802	CDK4	S33	P36S	36	Missense	distal	3	no	7.064	6.759	EPSD	COSMIC;GDSC;CCLE	2.642	Down-regulation
CMGC_CDK_CDK4_CDK4_ST	P04637	TP53	P11802	CDK4	S33	A39V	39	Missense	distal	6	no	7.064	6.944	EPSD	COSMIC	2.642	Down-regulation
CMGC_CDK_CDK4_CDK4_ST	P04637	TP53	P11802	CDK4	S33	A39S	39	Missense	distal	6	no	7.064	7.142	EPSD	COSMIC	2.642	Up-regulation
CMGC_CDK_CDK4_CDK4_ST	P04637	TP53	P11802	CDK4	S33	N30K	30	Missense	distal	-3	no	7.064	7.046	EPSD	COSMIC	2.642	Down-regulation
CMGC_CDK_CDK4_CDK4_ST	P04637	TP53	P11802	CDK4	S33	A39T	39	Missense	distal	6	no	7.064	7.020	EPSD	COSMIC	2.642	Down-regulation
CMGC_CDK_CDK4_CDK4_ST	P04637	TP53	P11802	CDK4	S33	P27T	27	Missense	distal	-6	no	7.064	7.042	EPSD	COSMIC	2.642	Down-regulation
CMGC_CDK_CDK4_CDK4_ST	P04637	TP53	P11802	CDK4	S33	P36R	36	Missense	distal	3	no	7.064	6.518	EPSD	COSMIC	2.642	Down-regulation
CMGC_CDK_CDK4_CDK4_ST	P04637	TP53	P11802	CDK4	S33	L35R	35	Missense	proximal	2	no	7.064	7.170	EPSD	COSMIC	2.642	Up-regulation
CMGC_CDK_CDK4_CDK4_ST	P04637	TP53	P11802	CDK4	S33	L35H	35	Missense	proximal	2	no	7.064	7.043	EPSD	COSMIC	2.642	Down-regulation
CMGC_CDK_CDK4_CDK4_ST	P04637	TP53	P11802	CDK4	S33	L35P	35	Missense	proximal	2	no	7.064	7.133	EPSD	COSMIC	2.642	Up-regulation
CMGC_CDK_CDK4_CDK4_ST	P04637	TP53	P11802	CDK4	S33	L35I	35	Missense	proximal	2	no	7.064	7.016	EPSD	COSMIC	2.642	Down-regulation
CMGC_CDK_CDK4_CDK4_ST	P04637	TP53	P11802	CDK4	S33	L35V	35	Missense	proximal	2	no	7.064	7.016	EPSD	COSMIC	2.642	Down-regulation
CMGC_CDK_CDK4_CDK4_ST	P04637	TP53	P11802	CDK4	S46	M40I	40	Missense	distal	-6	no	6.809	6.856	EPSD	COSMIC	2.642	Up-regulation
CMGC_CDK_CDK4_CDK4_ST	P04637	TP53	P11802	CDK4	S46	W53C	53	Missense	distal	7	no	6.809	6.808	EPSD	COSMIC	2.642	Down-regulation
CMGC_CDK_CDK4_CDK4_ST	P04637	TP53	P11802	CDK4	S46	W53G	53	Missense	distal	7	no	6.809	6.799	EPSD	COSMIC	2.642	Down-regulation
CMGC_CDK_CDK4_CDK4_ST	P04637	TP53	P11802	CDK4	S46	S46F	46	Missense	central	0	yes	6.809	0.000	EPSD	COSMIC	2.642	Loss
CMGC_CDK_CDK4_CDK4_ST	P04637	TP53	P11802	CDK4	S46	D49Y	49	Missense	distal	3	no	6.809	7.069	EPSD	COSMIC	2.642	Up-regulation
CMGC_CDK_CDK4_CDK4_ST	P04637	TP53	P11802	CDK4	S46	P47L	47	Missense	proximal	1	no	6.809	-0.771	EPSD	COSMIC	2.642	Loss
CMGC_CDK_CDK4_CDK4_ST	P04637	TP53	P11802	CDK4	S46	D49H	49	Missense	distal	3	no	6.809	7.015	EPSD	COSMIC;GDSC;CCLE	2.642	Up-regulation
CMGC_CDK_CDK4_CDK4_ST	P04637	TP53	P11802	CDK4	S46	P47S	47	Missense	proximal	1	no	6.809	0.622	EPSD	COSMIC	2.642	Loss
CMGC_CDK_CDK4_CDK4_ST	P04637	TP53	P11802	CDK4	S46	D41N	41	Missense	distal	-5	no	6.809	6.842	EPSD	COSMIC	2.642	Up-regulation
CMGC_CDK_CDK4_CDK4_ST	P04637	TP53	P11802	CDK4	S46	D48H	48	Missense	proximal	2	no	6.809	6.837	EPSD	COSMIC	2.642	Up-regulation
CMGC_CDK_CDK4_CDK4_ST	P04637	TP53	P11802	CDK4	S46	D49N	49	Missense	distal	3	no	6.809	7.176	EPSD	COSMIC	2.642	Up-regulation
CMGC_CDK_CDK4_CDK4_ST	P04637	TP53	P11802	CDK4	S46	M44I	44	Missense	proximal	-2	no	6.809	6.751	EPSD	COSMIC	2.642	Down-regulation
CMGC_CDK_CDK4_CDK4_ST	P04637	TP53	P11802	CDK4	S46	Q52H	52	Missense	distal	6	no	6.809	6.782	EPSD	COSMIC	2.642	Down-regulation
CMGC_CDK_CDK4_CDK4_ST	P04637	TP53	P11802	CDK4	S46	D49V	49	Missense	distal	3	no	6.809	6.871	EPSD	COSMIC	2.642	Up-regulation
CMGC_CDK_CDK4_CDK4_ST	P04637	TP53	P11802	CDK4	S46	A39V	39	Missense	distal	-7	no	6.809	6.323	EPSD	COSMIC	2.642	Down-regulation
CMGC_CDK_CDK4_CDK4_ST	P04637	TP53	P11802	CDK4	S46	A39S	39	Missense	distal	-7	no	6.809	7.025	EPSD	COSMIC	2.642	Up-regulation
CMGC_CDK_CDK4_CDK4_ST	P04637	TP53	P11802	CDK4	S46	D42Y	42	Missense	distal	-4	no	6.809	6.808	EPSD	COSMIC	2.642	Down-regulation
CMGC_CDK_CDK4_CDK4_ST	P04637	TP53	P11802	CDK4	S46	M44R	44	Missense	proximal	-2	no	6.809	6.864	EPSD	COSMIC	2.642	Up-regulation
CMGC_CDK_CDK4_CDK4_ST	P04637	TP53	P11802	CDK4	S46	S46P	46	Missense	central	0	yes	6.809	0.000	EPSD	COSMIC	2.642	Loss
CMGC_CDK_CDK4_CDK4_ST	P04637	TP53	P11802	CDK4	S46	M44V	44	Missense	proximal	-2	no	6.809	6.758	EPSD	COSMIC	2.642	Down-regulation
CMGC_CDK_CDK4_CDK4_ST	P04637	TP53	P11802	CDK4	S46	L45P	45	Missense	proximal	-1	no	6.809	6.771	EPSD	COSMIC	2.642	Down-regulation
CMGC_CDK_CDK4_CDK4_ST	P04637	TP53	P11802	CDK4	S46	M44T	44	Missense	proximal	-2	no	6.809	6.863	EPSD	COSMIC	2.642	Up-regulation
CMGC_CDK_CDK4_CDK4_ST	P04637	TP53	P11802	CDK4	S46	A39T	39	Missense	distal	-7	no	6.809	6.615	EPSD	COSMIC	2.642	Down-regulation
CMGC_CDK_CDK4_CDK4_ST	P04637	TP53	P11802	CDK4	S46	L43F	43	Missense	distal	-3	no	6.809	6.773	EPSD	COSMIC	2.642	Down-regulation
CMGC_CDK_CDK4_CDK4_ST	P04637	TP53	P11802	CDK4	S46	D41H	41	Missense	distal	-5	no	6.809	6.804	EPSD	COSMIC	2.642	Down-regulation
CMGC_CDK_CDK4_CDK4_ST	P04637	TP53	P11802	CDK4	S46	D49E	49	Missense	distal	3	no	6.809	7.103	EPSD	COSMIC	2.642	Up-regulation
CMGC_CDK_CDK4_CDK4_ST	P04637	TP53	P11802	CDK4	S46	D49G	49	Missense	distal	3	no	6.809	6.820	EPSD	COSMIC	2.642	Up-regulation
CMGC_CDK_CDK4_CDK4_ST	P04637	TP53	P11802	CDK4	S46	D48A	48	Missense	proximal	2	no	6.809	6.987	EPSD	COSMIC	2.642	Up-regulation
CMGC_CDK_CDK4_CDK4_ST	P04637	TP53	P11802	CDK4	S46	D48Y	48	Missense	proximal	2	no	6.809	6.866	EPSD	COSMIC	2.642	Up-regulation
CMGC_CDK_CDK4_CDK4_ST	P04637	TP53	P11802	CDK4	S46	D48E	48	Missense	proximal	2	no	6.809	6.895	EPSD	COSMIC	2.642	Up-regulation
CMGC_CDK_CDK4_CDK4_ST	P04637	TP53	P11802	CDK4	S46	D49I	49	Missense	distal	3	no	6.809	6.805	EPSD	COSMIC	2.642	Down-regulation
CMGC_CDK_CDK4_CDK4_ST	P04637	TP53	P11802	CDK4	S46	D41E	41	Missense	distal	-5	no	6.809	6.857	EPSD	COSMIC	2.642	Up-regulation
CMGC_CDK_CDK4_CDK4_ST	P04637	TP53	P11802	CDK4	T81	A76T	76	Missense	distal	-5	no	8.060	8.011	EPSD	COSMIC	2.642	Down-regulation
CMGC_CDK_CDK4_CDK4_ST	P04637	TP53	P11802	CDK4	T81	A83T	83	Missense	proximal	2	no	8.060	7.970	EPSD	COSMIC	2.642	Down-regulation
CMGC_CDK_CDK4_CDK4_ST	P04637	TP53	P11802	CDK4	T81	T81I	81	Missense	central	0	yes	8.060	0.000	EPSD	COSMIC	2.642	Loss
CMGC_CDK_CDK4_CDK4_ST	P04637	TP53	P11802	CDK4	T81	A84V	84	Missense	distal	3	no	8.060	7.636	EPSD	COSMIC	2.642	Down-regulation
CMGC_CDK_CDK4_CDK4_ST	P04637	TP53	P11802	CDK4	T81	P80L	80	Missense	proximal	-1	no	8.060	8.097	EPSD	COSMIC	2.642	Up-regulation
CMGC_CDK_CDK4_CDK4_ST	P04637	TP53	P11802	CDK4	T81	A86V	86	Missense	distal	5	no	8.060	8.087	EPSD	COSMIC	2.642	Up-regulation
CMGC_CDK_CDK4_CDK4_ST	P04637	TP53	P11802	CDK4	T81	P85S	85	Missense	distal	4	no	8.060	7.853	EPSD	COSMIC	2.642	Down-regulation
CMGC_CDK_CDK4_CDK4_ST	P04637	TP53	P11802	CDK4	T81	A79T	79	Missense	proximal	-2	no	8.060	8.038	EPSD	COSMIC	2.642	Down-regulation
CMGC_CDK_CDK4_CDK4_ST	P04637	TP53	P11802	CDK4	T81	A84G	84	Missense	distal	3	no	8.060	7.585	EPSD	COSMIC	2.642	Down-regulation
CMGC_CDK_CDK4_CDK4_ST	P04637	TP53	P11802	CDK4	T81	A78V	78	Missense	distal	-3	no	8.060	8.172	EPSD	COSMIC	2.642	Up-regulation
CMGC_CDK_CDK4_CDK4_ST	P04637	TP53	P11802	CDK4	T81	A78S	78	Missense	distal	-3	no	8.060	7.996	EPSD	COSMIC	2.642	Down-regulation
CMGC_CDK_CDK4_CDK4_ST	P04637	TP53	P11802	CDK4	T81	P87L	87	Missense	distal	6	no	8.060	8.038	EPSD	COSMIC	2.642	Down-regulation
CMGC_CDK_CDK4_CDK4_ST	P04637	TP53	P11802	CDK4	T81	P85L	85	Missense	distal	4	no	8.060	8.221	EPSD	COSMIC	2.642	Up-regulation
CMGC_CDK_CDK4_CDK4_ST	P04637	TP53	P11802	CDK4	T81	P82S	82	Missense	proximal	1	no	8.060	1.873	EPSD	COSMIC	2.642	Loss
CMGC_CDK_CDK4_CDK4_ST	P04637	TP53	P11802	CDK4	T81	P80S	80	Missense	proximal	-1	no	8.060	7.812	EPSD	COSMIC	2.642	Down-regulation
CMGC_CDK_CDK4_CDK4_ST	P04637	TP53	P11802	CDK4	T81	A84T	84	Missense	distal	3	no	8.060	7.899	EPSD	COSMIC	2.642	Down-regulation
CMGC_CDK_CDK4_CDK4_ST	P04637	TP53	P11802	CDK4	T81	A83E	83	Missense	proximal	2	no	8.060	7.968	EPSD	COSMIC	2.642	Down-regulation
CMGC_CDK_CDK4_CDK4_ST	P04637	TP53	P11802	CDK4	T81	P85T	85	Missense	distal	4	no	8.060	8.081	EPSD	COSMIC	2.642	Up-regulation
CMGC_CDK_CDK4_CDK4_ST	P04637	TP53	P11802	CDK4	T81	A74V	74	Missense	distal	-7	no	8.060	7.575	EPSD	COSMIC	2.642	Down-regulation
CMGC_CDK_CDK4_CDK4_ST	P04637	TP53	P11802	CDK4	T81	P75S	75	Missense	distal	-6	no	8.060	7.850	EPSD	COSMIC	2.642	Down-regulation
CMGC_CDK_CDK4_CDK4_ST	P04637	TP53	P11802	CDK4	T81	A76V	76	Missense	distal	-5	no	8.060	7.954	EPSD	COSMIC	2.642	Down-regulation
CMGC_CDK_CDK4_CDK4_ST	P04637	TP53	P11802	CDK4	T81	P75R	75	Missense	distal	-6	no	8.060	8.121	EPSD	COSMIC	2.642	Up-regulation
CMGC_CDK_CDK4_CDK4_ST	P04637	TP53	P11802	CDK4	T81	P87H	87	Missense	distal	6	no	8.060	8.032	EPSD	COSMIC	2.642	Down-regulation
CMGC_CDK_CDK4_CDK4_ST	P04637	TP53	P11802	CDK4	T81	P87T	87	Missense	distal	6	no	8.060	8.096	EPSD	COSMIC	2.642	Up-regulation
CMGC_CDK_CDK4_CDK4_ST	P04637	TP53	P11802	CDK4	T81	P87S	87	Missense	distal	6	no	8.060	8.218	EPSD	COSMIC	2.642	Up-regulation
CMGC_CDK_CDK4_CDK4_ST	P04637	TP53	P11802	CDK4	T81	P87R	87	Missense	distal	6	no	8.060	8.106	EPSD	COSMIC	2.642	Up-regulation
CMGC_CDK_CDK4_CDK4_ST	P04637	TP53	P11802	CDK4	T81	P87C	87	Missense	distal	6	no	8.060	8.001	EPSD	COSMIC	2.642	Down-regulation
CMGC_CDK_CDK4_CDK4_ST	P04637	TP53	P11802	CDK4	T81	A86E	86	Missense	distal	5	no	8.060	8.072	EPSD	COSMIC	2.642	Up-regulation
CMGC_CDK_CDK4_CDK4_ST	P04637	TP53	P11802	CDK4	T81	A86S	86	Missense	distal	5	no	8.060	8.046	EPSD	COSMIC	2.642	Down-regulation
CMGC_CDK_CDK4_CDK4_ST	P04637	TP53	P11802	CDK4	T81	A83V	83	Missense	proximal	2	no	8.060	7.883	EPSD	COSMIC	2.642	Down-regulation
CMGC_CDK_CDK4_CDK4_ST	P04637	TP53	P11802	CDK4	S99	T102P	102	Missense	distal	3	no	2.211	3.005	EPSD	COSMIC	2.642	Gain
CMGC_CDK_CDK4_CDK4_ST	P04637	TP53	P11802	CDK4	S127	C124W	124	Missense	distal	-3	no	7.138	7.137	EPSD	COSMIC	2.642	Down-regulation
CMGC_CDK_CDK4_CDK4_ST	P04637	TP53	P11802	CDK4	S127	C124F	124	Missense	distal	-3	no	7.138	7.111	EPSD	COSMIC	2.642	Down-regulation
CMGC_CDK_CDK4_CDK4_ST	P04637	TP53	P11802	CDK4	S127	C124S	124	Missense	distal	-3	no	7.138	6.964	EPSD	COSMIC	2.642	Down-regulation
CMGC_CDK_CDK4_CDK4_ST	P04637	TP53	P11802	CDK4	S127	S127A	127	Missense	central	0	yes	7.138	0.000	EPSD	COSMIC	2.642	Loss
CMGC_CDK_CDK4_CDK4_ST	P04637	TP53	P11802	CDK4	S127	S127L	127	Missense	central	0	yes	7.138	0.000	EPSD	COSMIC	2.642	Loss
CMGC_CDK_CDK4_CDK4_ST	P04637	TP53	P11802	CDK4	S127	C124T	124	Missense	distal	-3	no	7.138	7.064	EPSD	COSMIC	2.642	Down-regulation
CMGC_CDK_CDK4_CDK4_ST	P04637	TP53	P11802	CDK4	S127	S127I	127	Missense	central	0	yes	7.138	0.000	EPSD	COSMIC	2.642	Loss
CMGC_CDK_CDK4_CDK4_ST	P04637	TP53	P11802	CDK4	S127	S127G	127	Missense	central	0	yes	7.138	0.000	EPSD	COSMIC	2.642	Loss
CMGC_CDK_CDK4_CDK4_ST	P04637	TP53	P11802	CDK4	S127	N131H	131	Missense	distal	4	no	7.138	7.262	EPSD	COSMIC	2.642	Up-regulation
CMGC_CDK_CDK4_CDK4_ST	P04637	TP53	P11802	CDK4	S127	N131D	131	Missense	distal	4	no	7.138	7.304	EPSD	COSMIC	2.642	Up-regulation
CMGC_CDK_CDK4_CDK4_ST	P04637	TP53	P11802	CDK4	S127	T125I	125	Missense	proximal	-2	no	7.138	7.026	EPSD	COSMIC	2.642	Down-regulation
CMGC_CDK_CDK4_CDK4_ST	P04637	TP53	P11802	CDK4	S127	F134I	134	Missense	distal	7	no	7.138	7.137	EPSD	COSMIC	2.642	Down-regulation
CMGC_CDK_CDK4_CDK4_ST	P04637	TP53	P11802	CDK4	S127	K120T	120	Missense	distal	-7	no	7.138	7.157	EPSD	COSMIC	2.642	Up-regulation
CMGC_CDK_CDK4_CDK4_ST	P04637	TP53	P11802	CDK4	S127	F134S	134	Missense	distal	7	no	7.138	7.163	EPSD	COSMIC	2.642	Up-regulation
CMGC_CDK_CDK4_CDK4_ST	P04637	TP53	P11802	CDK4	S127	T125K	125	Missense	proximal	-2	no	7.138	7.156	EPSD	COSMIC	2.642	Up-regulation
CMGC_CDK_CDK4_CDK4_ST	P04637	TP53	P11802	CDK4	S127	M133I	133	Missense	distal	6	no	7.138	7.127	EPSD	COSMIC	2.642	Down-regulation
CMGC_CDK_CDK4_CDK4_ST	P04637	TP53	P11802	CDK4	S127	N131K	131	Missense	distal	4	no	7.138	7.088	EPSD	COSMIC;CCLE	2.642	Down-regulation
CMGC_CDK_CDK4_CDK4_ST	P04637	TP53	P11802	CDK4	S127	P128S	128	Missense	proximal	1	no	7.138	0.951	EPSD	COSMIC	2.642	Loss
CMGC_CDK_CDK4_CDK4_ST	P04637	TP53	P11802	CDK4	S127	M133L	133	Missense	distal	6	no	7.138	7.145	EPSD	COSMIC	2.642	Up-regulation
CMGC_CDK_CDK4_CDK4_ST	P04637	TP53	P11802	CDK4	S127	A129T	129	Missense	proximal	2	no	7.138	7.048	EPSD	COSMIC	2.642	Down-regulation
CMGC_CDK_CDK4_CDK4_ST	P04637	TP53	P11802	CDK4	S127	T123I	123	Missense	distal	-4	no	7.138	7.139	EPSD	COSMIC	2.642	Up-regulation
CMGC_CDK_CDK4_CDK4_ST	P04637	TP53	P11802	CDK4	S127	A129G	129	Missense	proximal	2	no	7.138	6.802	EPSD	COSMIC	2.642	Down-regulation
CMGC_CDK_CDK4_CDK4_ST	P04637	TP53	P11802	CDK4	S127	K132W	132	Missense	distal	5	no	7.138	7.158	EPSD	COSMIC	2.642	Up-regulation
CMGC_CDK_CDK4_CDK4_ST	P04637	TP53	P11802	CDK4	S127	A129V	129	Missense	proximal	2	no	7.138	6.961	EPSD	COSMIC	2.642	Down-regulation
CMGC_CDK_CDK4_CDK4_ST	P04637	TP53	P11802	CDK4	S127	P128A	128	Missense	proximal	1	no	7.138	0.200	EPSD	COSMIC	2.642	Loss
CMGC_CDK_CDK4_CDK4_ST	P04637	TP53	P11802	CDK4	S127	L130I	130	Missense	distal	3	no	7.138	6.914	EPSD	COSMIC	2.642	Down-regulation
CMGC_CDK_CDK4_CDK4_ST	P04637	TP53	P11802	CDK4	S127	S121F	121	Missense	distal	-6	no	7.138	7.506	EPSD	COSMIC	2.642	Up-regulation
CMGC_CDK_CDK4_CDK4_ST	P04637	TP53	P11802	CDK4	S127	A129D	129	Missense	proximal	2	no	7.138	6.960	EPSD	COSMIC	2.642	Down-regulation
CMGC_CDK_CDK4_CDK4_ST	P04637	TP53	P11802	CDK4	S127	K120Q	120	Missense	distal	-7	no	7.138	7.021	EPSD	COSMIC	2.642	Down-regulation
CMGC_CDK_CDK4_CDK4_ST	P04637	TP53	P11802	CDK4	S127	T125S	125	Missense	proximal	-2	no	7.138	7.254	EPSD	COSMIC	2.642	Up-regulation
CMGC_CDK_CDK4_CDK4_ST	P04637	TP53	P11802	CDK4	S127	P128L	128	Missense	proximal	1	no	7.138	-0.441	EPSD	COSMIC	2.642	Loss
CMGC_CDK_CDK4_CDK4_ST	P04637	TP53	P11802	CDK4	S127	V122L	122	Missense	distal	-5	no	7.138	7.128	EPSD	COSMIC	2.642	Down-regulation
CMGC_CDK_CDK4_CDK4_ST	P04637	TP53	P11802	CDK4	S127	C124L	124	Missense	distal	-3	no	7.138	7.147	EPSD	COSMIC	2.642	Up-regulation
CMGC_CDK_CDK4_CDK4_ST	P04637	TP53	P11802	CDK4	S127	N131T	131	Missense	distal	4	no	7.138	7.139	EPSD	COSMIC	2.642	Up-regulation
CMGC_CDK_CDK4_CDK4_ST	P04637	TP53	P11802	CDK4	S127	M133V	133	Missense	distal	6	no	7.138	7.127	EPSD	COSMIC	2.642	Down-regulation
CMGC_CDK_CDK4_CDK4_ST	P04637	TP53	P11802	CDK4	S149	P142S	142	Missense	distal	-7	no	2.468	2.668	EPSD	COSMIC	2.642	Gain
CMGC_CDK_CDK4_CDK4_ST	P04637	TP53	P11802	CDK4	S149	D148G	148	Missense	proximal	-1	no	2.468	2.661	EPSD	COSMIC	2.642	Gain
CMGC_CDK_CDK4_CDK4_ST	P04637	TP53	P11802	CDK4	S149	P153F	153	Missense	distal	4	no	2.468	2.658	EPSD	COSMIC	2.642	Gain
CMGC_CDK_CDK4_CDK4_ST	P04637	TP53	P11802	CDK4	T150	P151N	151	Missense	proximal	1	no	7.199	0.512	EPSD	COSMIC	2.642	Loss
CMGC_CDK_CDK4_CDK4_ST	P04637	TP53	P11802	CDK4	T150	P152A	152	Missense	proximal	2	no	7.199	7.259	EPSD	COSMIC	2.642	Up-regulation
CMGC_CDK_CDK4_CDK4_ST	P04637	TP53	P11802	CDK4	T150	P152T	152	Missense	proximal	2	no	7.199	7.169	EPSD	COSMIC	2.642	Down-regulation
CMGC_CDK_CDK4_CDK4_ST	P04637	TP53	P11802	CDK4	T150	P152H	152	Missense	proximal	2	no	7.199	7.110	EPSD	COSMIC	2.642	Down-regulation
CMGC_CDK_CDK4_CDK4_ST	P04637	TP53	P11802	CDK4	T150	P153T	153	Missense	distal	3	no	7.199	6.405	EPSD	COSMIC	2.642	Down-regulation
CMGC_CDK_CDK4_CDK4_ST	P04637	TP53	P11802	CDK4	T150	V147I	147	Missense	distal	-3	no	7.199	7.209	EPSD	COSMIC	2.642	Up-regulation
CMGC_CDK_CDK4_CDK4_ST	P04637	TP53	P11802	CDK4	T150	P153L	153	Missense	distal	3	no	7.199	6.300	EPSD	COSMIC	2.642	Down-regulation
CMGC_CDK_CDK4_CDK4_ST	P04637	TP53	P11802	CDK4	T150	V147D	147	Missense	distal	-3	no	7.199	7.200	EPSD	COSMIC;GDSC;CCLE	2.642	Up-regulation
CMGC_CDK_CDK4_CDK4_ST	P04637	TP53	P11802	CDK4	T150	S149P	149	Missense	proximal	-1	no	7.199	7.447	EPSD	COSMIC	2.642	Up-regulation
CMGC_CDK_CDK4_CDK4_ST	P04637	TP53	P11802	CDK4	T150	P152K	152	Missense	proximal	2	no	7.199	7.253	EPSD	COSMIC	2.642	Up-regulation
CMGC_CDK_CDK4_CDK4_ST	P04637	TP53	P11802	CDK4	T150	P153S	153	Missense	distal	3	no	7.199	6.894	EPSD	COSMIC	2.642	Down-regulation
CMGC_CDK_CDK4_CDK4_ST	P04637	TP53	P11802	CDK4	T150	G154C	154	Missense	distal	4	no	7.199	7.026	EPSD	COSMIC	2.642	Down-regulation
CMGC_CDK_CDK4_CDK4_ST	P04637	TP53	P11802	CDK4	T150	S149F	149	Missense	proximal	-1	no	7.199	7.566	EPSD	COSMIC	2.642	Up-regulation
CMGC_CDK_CDK4_CDK4_ST	P04637	TP53	P11802	CDK4	T150	G154D	154	Missense	distal	4	no	7.199	7.023	EPSD	COSMIC	2.642	Down-regulation
CMGC_CDK_CDK4_CDK4_ST	P04637	TP53	P11802	CDK4	T150	V157I	157	Missense	distal	7	no	7.199	7.198	EPSD	COSMIC	2.642	Down-regulation
CMGC_CDK_CDK4_CDK4_ST	P04637	TP53	P11802	CDK4	T150	Q144R	144	Missense	distal	-6	no	7.199	7.194	EPSD	COSMIC	2.642	Down-regulation
CMGC_CDK_CDK4_CDK4_ST	P04637	TP53	P11802	CDK4	T150	D148V	148	Missense	proximal	-2	no	7.199	7.178	EPSD	COSMIC	2.642	Down-regulation
CMGC_CDK_CDK4_CDK4_ST	P04637	TP53	P11802	CDK4	T150	S149Y	149	Missense	proximal	-1	no	7.199	7.445	EPSD	COSMIC	2.642	Up-regulation
CMGC_CDK_CDK4_CDK4_ST	P04637	TP53	P11802	CDK4	T150	T150I	150	Missense	central	0	yes	7.199	0.000	EPSD	COSMIC	2.642	Loss
CMGC_CDK_CDK4_CDK4_ST	P04637	TP53	P11802	CDK4	T150	S149T	149	Missense	proximal	-1	no	7.199	7.408	EPSD	COSMIC	2.642	Up-regulation
CMGC_CDK_CDK4_CDK4_ST	P04637	TP53	P11802	CDK4	T150	L145M	145	Missense	distal	-5	no	7.199	7.223	EPSD	COSMIC	2.642	Up-regulation
CMGC_CDK_CDK4_CDK4_ST	P04637	TP53	P11802	CDK4	T150	V143L	143	Missense	distal	-7	no	7.199	7.221	EPSD	COSMIC	2.642	Up-regulation
CMGC_CDK_CDK4_CDK4_ST	P04637	TP53	P11802	CDK4	T150	R156S	156	Missense	distal	6	no	7.199	7.310	EPSD	COSMIC	2.642	Up-regulation
CMGC_CDK_CDK4_CDK4_ST	P04637	TP53	P11802	CDK4	T150	D148E	148	Missense	proximal	-2	no	7.199	7.247	EPSD	COSMIC	2.642	Up-regulation
CMGC_CDK_CDK4_CDK4_ST	P04637	TP53	P11802	CDK4	T150	V147F	147	Missense	distal	-3	no	7.199	7.170	EPSD	COSMIC	2.642	Down-regulation
CMGC_CDK_CDK4_CDK4_ST	P04637	TP53	P11802	CDK4	T150	T155A	155	Missense	distal	5	no	7.199	7.191	EPSD	COSMIC	2.642	Down-regulation
CMGC_CDK_CDK4_CDK4_ST	P04637	TP53	P11802	CDK4	T150	V147E	147	Missense	distal	-3	no	7.199	7.136	EPSD	COSMIC	2.642	Down-regulation
CMGC_CDK_CDK4_CDK4_ST	P04637	TP53	P11802	CDK4	T150	G154I	154	Missense	distal	4	no	7.199	7.021	EPSD	COSMIC	2.642	Down-regulation
CMGC_CDK_CDK4_CDK4_ST	P04637	TP53	P11802	CDK4	T150	D148G	148	Missense	proximal	-2	no	7.199	7.208	EPSD	COSMIC	2.642	Up-regulation
CMGC_CDK_CDK4_CDK4_ST	P04637	TP53	P11802	CDK4	T150	Q144K	144	Missense	distal	-6	no	7.199	7.155	EPSD	COSMIC	2.642	Down-regulation
CMGC_CDK_CDK4_CDK4_ST	P04637	TP53	P11802	CDK4	T150	V147A	147	Missense	distal	-3	no	7.199	7.087	EPSD	COSMIC	2.642	Down-regulation
CMGC_CDK_CDK4_CDK4_ST	P04637	TP53	P11802	CDK4	T150	L145V	145	Missense	distal	-5	no	7.199	7.209	EPSD	COSMIC	2.642	Up-regulation
CMGC_CDK_CDK4_CDK4_ST	P04637	TP53	P11802	CDK4	T150	T150K	150	Missense	central	0	yes	7.199	0.000	EPSD	COSMIC	2.642	Loss
CMGC_CDK_CDK4_CDK4_ST	P04637	TP53	P11802	CDK4	T150	P153H	153	Missense	distal	3	no	7.199	6.286	EPSD	COSMIC	2.642	Down-regulation
CMGC_CDK_CDK4_CDK4_ST	P04637	TP53	P11802	CDK4	T150	V157E	157	Missense	distal	7	no	7.199	7.209	EPSD	COSMIC	2.642	Up-regulation
CMGC_CDK_CDK4_CDK4_ST	P04637	TP53	P11802	CDK4	T150	T155S	155	Missense	distal	5	no	7.199	7.177	EPSD	COSMIC;CCLE	2.642	Down-regulation
CMGC_CDK_CDK4_CDK4_ST	P04637	TP53	P11802	CDK4	T150	D148H	148	Missense	proximal	-2	no	7.199	7.249	EPSD	COSMIC	2.642	Up-regulation
CMGC_CDK_CDK4_CDK4_ST	P04637	TP53	P11802	CDK4	T150	P153A	153	Missense	distal	3	no	7.199	6.566	EPSD	COSMIC	2.642	Down-regulation
CMGC_CDK_CDK4_CDK4_ST	P04637	TP53	P11802	CDK4	T150	T150R	150	Missense	central	0	yes	7.199	0.000	EPSD	COSMIC	2.642	Loss
CMGC_CDK_CDK4_CDK4_ST	P04637	TP53	P11802	CDK4	T150	T155L	155	Missense	distal	5	no	7.199	7.213	EPSD	COSMIC	2.642	Up-regulation
CMGC_CDK_CDK4_CDK4_ST	P04637	TP53	P11802	CDK4	T150	G154A	154	Missense	distal	4	no	7.199	6.723	EPSD	COSMIC	2.642	Down-regulation
CMGC_CDK_CDK4_CDK4_ST	P04637	TP53	P11802	CDK4	T150	T150A	150	Missense	central	0	yes	7.199	0.000	EPSD	COSMIC	2.642	Loss
CMGC_CDK_CDK4_CDK4_ST	P04637	TP53	P11802	CDK4	T150	P153F	153	Missense	distal	3	no	7.199	6.303	EPSD	COSMIC	2.642	Down-regulation
CMGC_CDK_CDK4_CDK4_ST	P04637	TP53	P11802	CDK4	T150	D148Y	148	Missense	proximal	-2	no	7.199	7.250	EPSD	COSMIC	2.642	Up-regulation
CMGC_CDK_CDK4_CDK4_ST	P04637	TP53	P11802	CDK4	T150	G154R	154	Missense	distal	4	no	7.199	6.862	EPSD	COSMIC	2.642	Down-regulation
CMGC_CDK_CDK4_CDK4_ST	P04637	TP53	P11802	CDK4	S313	S314F	314	Missense	proximal	1	no	2.119	2.642	EPSD	COSMIC	2.642	Gain
CMGC_CDK_CDK4_CDK4_ST	P04637	TP53	P11802	CDK4	S314	S315P	315	Missense	proximal	1	no	1.527	7.714	EPSD	COSMIC	2.642	Gain
CMGC_CDK_CDK4_CDK4_ST	P04637	TP53	P11802	CDK4	S315	N310T	310	Missense	distal	-5	no	8.449	8.459	EPSD	COSMIC	2.642	Up-regulation
CMGC_CDK_CDK4_CDK4_ST	P04637	TP53	P11802	CDK4	S315	Q317R	317	Missense	proximal	2	no	8.449	8.557	EPSD	COSMIC	2.642	Up-regulation
CMGC_CDK_CDK4_CDK4_ST	P04637	TP53	P11802	CDK4	S315	P309S	309	Missense	distal	-6	no	8.449	8.240	EPSD	COSMIC;GDSC;CCLE	2.642	Down-regulation
CMGC_CDK_CDK4_CDK4_ST	P04637	TP53	P11802	CDK4	S315	K319E	319	Missense	distal	4	no	8.449	8.500	EPSD	COSMIC	2.642	Up-regulation
CMGC_CDK_CDK4_CDK4_ST	P04637	TP53	P11802	CDK4	S315	P322L	322	Missense	distal	7	no	8.449	8.433	EPSD	COSMIC	2.642	Down-regulation
CMGC_CDK_CDK4_CDK4_ST	P04637	TP53	P11802	CDK4	S315	K320N	320	Missense	distal	5	no	8.449	8.454	EPSD	COSMIC;GDSC;CCLE	2.642	Up-regulation
CMGC_CDK_CDK4_CDK4_ST	P04637	TP53	P11802	CDK4	S315	N310L	310	Missense	distal	-5	no	8.449	8.391	EPSD	COSMIC	2.642	Down-regulation
CMGC_CDK_CDK4_CDK4_ST	P04637	TP53	P11802	CDK4	S315	T312S	312	Missense	distal	-3	no	8.449	8.350	EPSD	COSMIC	2.642	Down-regulation
CMGC_CDK_CDK4_CDK4_ST	P04637	TP53	P11802	CDK4	S315	N311Y	311	Missense	distal	-4	no	8.449	8.450	EPSD	COSMIC	2.642	Up-regulation
CMGC_CDK_CDK4_CDK4_ST	P04637	TP53	P11802	CDK4	S315	P322R	322	Missense	distal	7	no	8.449	8.443	EPSD	COSMIC	2.642	Down-regulation
CMGC_CDK_CDK4_CDK4_ST	P04637	TP53	P11802	CDK4	S315	Q317K	317	Missense	proximal	2	no	8.449	8.574	EPSD	COSMIC	2.642	Up-regulation
CMGC_CDK_CDK4_CDK4_ST	P04637	TP53	P11802	CDK4	S315	S315P	315	Missense	central	0	yes	8.449	0.000	EPSD	COSMIC	2.642	Loss
CMGC_CDK_CDK4_CDK4_ST	P04637	TP53	P11802	CDK4	S315	N310H	310	Missense	distal	-5	no	8.449	8.411	EPSD	COSMIC	2.642	Down-regulation
CMGC_CDK_CDK4_CDK4_ST	P04637	TP53	P11802	CDK4	S315	S314C	314	Missense	proximal	-1	no	8.449	8.789	EPSD	COSMIC	2.642	Up-regulation
CMGC_CDK_CDK4_CDK4_ST	P04637	TP53	P11802	CDK4	S315	P318A	318	Missense	distal	3	no	8.449	7.816	EPSD	COSMIC	2.642	Down-regulation
CMGC_CDK_CDK4_CDK4_ST	P04637	TP53	P11802	CDK4	S315	P316L	316	Missense	proximal	1	no	8.449	0.870	EPSD	COSMIC	2.642	Loss
CMGC_CDK_CDK4_CDK4_ST	P04637	TP53	P11802	CDK4	S315	L308M	308	Missense	distal	-7	no	8.449	8.505	EPSD	COSMIC	2.642	Up-regulation
CMGC_CDK_CDK4_CDK4_ST	P04637	TP53	P11802	CDK4	S315	S313C	313	Missense	proximal	-2	no	8.449	8.249	EPSD	COSMIC	2.642	Down-regulation
CMGC_CDK_CDK4_CDK4_ST	P04637	TP53	P11802	CDK4	S315	N311H	311	Missense	distal	-4	no	8.449	8.450	EPSD	COSMIC	2.642	Up-regulation
CMGC_CDK_CDK4_CDK4_ST	P04637	TP53	P11802	CDK4	S315	L308V	308	Missense	distal	-7	no	8.449	8.428	EPSD	COSMIC	2.642	Down-regulation
CMGC_CDK_CDK4_CDK4_ST	P04637	TP53	P11802	CDK4	S315	S314F	314	Missense	proximal	-1	no	8.449	8.817	EPSD	COSMIC	2.642	Up-regulation
CMGC_CDK_CDK4_CDK4_ST	P04637	TP53	P11802	CDK4	S315	K319R	319	Missense	distal	4	no	8.449	8.504	EPSD	COSMIC	2.642	Up-regulation
CMGC_CDK_CDK4_CDK4_ST	P04637	TP53	P11802	CDK4	S315	T312A	312	Missense	distal	-3	no	8.449	8.414	EPSD	COSMIC	2.642	Down-regulation
CMGC_CDK_CDK4_CDK4_ST	P04637	TP53	P11802	CDK4	S315	N310D	310	Missense	distal	-5	no	8.449	8.416	EPSD	COSMIC	2.642	Down-regulation
CMGC_CDK_CDK4_CDK4_ST	P04637	TP53	P11802	CDK4	S315	N311D	311	Missense	distal	-4	no	8.449	8.450	EPSD	COSMIC	2.642	Up-regulation
CMGC_CDK_CDK4_CDK4_ST	P04637	TP53	P11802	CDK4	S315	P309R	309	Missense	distal	-6	no	8.449	8.510	EPSD	COSMIC	2.642	Up-regulation
CMGC_CDK_CDK4_CDK4_ST	P04637	TP53	P11802	CDK4	S315	S313N	313	Missense	proximal	-2	no	8.449	8.321	EPSD	COSMIC	2.642	Down-regulation
CMGC_CDK_CDK4_CDK4_ST	P04637	TP53	P11802	CDK4	S315	Q317P	317	Missense	proximal	2	no	8.449	8.520	EPSD	COSMIC	2.642	Up-regulation
CMGC_CDK_CDK4_CDK4_ST	P04637	TP53	P11802	CDK4	S315	P316S	316	Missense	proximal	1	no	8.449	2.262	EPSD	COSMIC	2.642	Loss
CMGC_CDK_CDK4_CDK4_ST	P04637	TP53	P11802	CDK4	S378	R379P	379	Missense	proximal	1	no	1.814	8.601	EPSD	COSMIC	2.642	Gain
CMGC_CDK_CDK4_CDK4_ST	P28749	RBL1	P11802	CDK4	T332	F336L	336	Missense	distal	4	no	7.964	7.934	EPSD	COSMIC	2.642	Down-regulation
CMGC_CDK_CDK4_CDK4_ST	P28749	RBL1	P11802	CDK4	T340	P341Q	341	Missense	proximal	1	no	6.833	-0.336	EPSD	COSMIC	2.642	Loss
CMGC_CDK_CDK4_CDK4_ST	P28749	RBL1	P11802	CDK4	T369	R374Q	374	Missense	distal	5	no	7.842	7.850	EPSD;PhosphoSitePlus	COSMIC	2.642	Up-regulation
CMGC_CDK_CDK4_CDK4_ST	P28749	RBL1	P11802	CDK4	T385	A382T	382	Missense	distal	-3	no	6.496	6.531	EPSD	COSMIC	2.642	Up-regulation
CMGC_CDK_CDK4_CDK4_ST	P28749	RBL1	P11802	CDK4	S615	P616S	616	Missense	proximal	1	no	7.431	1.244	EPSD	COSMIC	2.642	Loss
CMGC_CDK_CDK4_CDK4_ST	P28749	RBL1	P11802	CDK4	S629	V622F	622	Missense	distal	-7	no	3.690	3.679	EPSD	COSMIC	2.642	Down-regulation
CMGC_CDK_CDK4_CDK4_ST	P28749	RBL1	P11802	CDK4	S640	P641L	641	Missense	proximal	1	no	10.648	3.069	EPSD;PhosphoSitePlus	COSMIC	2.642	Down-regulation
CMGC_CDK_CDK4_CDK4_ST	P28749	RBL1	P11802	CDK4	S640	P641Q	641	Missense	proximal	1	no	10.648	3.479	EPSD;PhosphoSitePlus	COSMIC	2.642	Down-regulation
CMGC_CDK_CDK4_CDK4_ST	P28749	RBL1	P11802	CDK4	S640	H645N	645	Missense	distal	5	no	10.648	10.640	EPSD;PhosphoSitePlus	COSMIC;GDSC;CCLE	2.642	Down-regulation
CMGC_CDK_CDK4_CDK4_ST	P28749	RBL1	P11802	CDK4	S650	S649C	649	Missense	proximal	-1	no	9.588	9.927	EPSD	COSMIC;GDSC;CCLE	2.642	Up-regulation
CMGC_CDK_CDK4_CDK4_ST	P28749	RBL1	P11802	CDK4	S650	S655N	655	Missense	distal	5	no	9.588	9.612	EPSD	COSMIC	2.642	Up-regulation
CMGC_CDK_CDK4_CDK4_ST	P28749	RBL1	P11802	CDK4	S650	H645N	645	Missense	distal	-5	no	9.588	9.626	EPSD	COSMIC;GDSC;CCLE	2.642	Up-regulation
CMGC_CDK_CDK4_CDK4_ST	P28749	RBL1	P11802	CDK4	T915	D908Y	908	Missense	distal	-7	no	6.714	6.733	EPSD	COSMIC	2.642	Up-regulation
CMGC_CDK_CDK4_CDK4_ST	P28749	RBL1	P11802	CDK4	S964	D959G	959	Missense	distal	-5	no	8.450	8.349	PhosphoSitePlus;EPSD	COSMIC	2.642	Down-regulation
CMGC_CDK_CDK4_CDK4_ST	P28749	RBL1	P11802	CDK4	S964	P967S	967	Missense	distal	3	no	8.450	8.145	PhosphoSitePlus;EPSD	COSMIC	2.642	Down-regulation
CMGC_CDK_CDK4_CDK4_ST	P28749	RBL1	P11802	CDK4	S964	P965A	965	Missense	proximal	1	no	8.450	1.512	PhosphoSitePlus;EPSD	COSMIC	2.642	Loss
CMGC_CDK_CDK4_CDK4_ST	P28749	RBL1	P11802	CDK4	S988	S988F	988	Missense	central	0	yes	5.437	0.000	EPSD	COSMIC	2.642	Loss
CMGC_CDK_CDK4_CDK4_ST	P28749	RBL1	P11802	CDK4	S988	P989S	989	Missense	proximal	1	no	5.437	-0.750	EPSD	COSMIC	2.642	Loss
CMGC_CDK_CDK4_CDK4_ST	P28749	RBL1	P11802	CDK4	S994	S988F	988	Missense	distal	-6	no	3.474	3.843	EPSD	COSMIC	2.642	Up-regulation
CMGC_CDK_CDK4_CDK4_ST	P28749	RBL1	P11802	CDK4	S994	P989S	989	Missense	distal	-5	no	3.474	3.611	EPSD	COSMIC	2.642	Up-regulation
CMGC_CDK_CDK4_CDK4_ST	P28749	RBL1	P11802	CDK4	S1009	P1010H	1010	Missense	proximal	1	no	7.843	1.260	EPSD	COSMIC	2.642	Loss
CMGC_CDK_CDK4_CDK4_ST	P28749	RBL1	P11802	CDK4	S1009	G1008F	1008	Missense	proximal	-1	no	7.843	7.695	EPSD	COSMIC	2.642	Down-regulation
CMGC_CDK_CDK4_CDK4_ST	P28749	RBL1	P11802	CDK4	S1009	D1016H	1016	Missense	distal	7	no	7.843	7.846	EPSD	COSMIC;GDSC;CCLE	2.642	Up-regulation
CMGC_CDK_CDK4_CDK4_ST	P28749	RBL1	P11802	CDK4	S1041	P1042S	1042	Missense	proximal	1	no	8.778	2.591	EPSD	COSMIC	2.642	Loss
CMGC_CDK_CDK4_CDK4_ST	P28749	RBL1	P11802	CDK4	S1041	K1044E	1044	Missense	distal	3	no	8.778	8.490	EPSD	COSMIC;GDSC;CCLE	2.642	Down-regulation
CMGC_CDK_CDK4_CDK4_ST	P28749	RBL1	P11802	CDK4	S1041	D1038G	1038	Missense	distal	-3	no	8.778	8.824	EPSD	COSMIC	2.642	Up-regulation
CMGC_CDK_CDK4_CDK4_ST	P28749	RBL1	P11802	CDK4	S1041	P1042L	1042	Missense	proximal	1	no	8.778	1.199	EPSD	COSMIC	2.642	Loss
CMGC_CDK_CDK4_CDK4_ST	P28749	RBL1	P11802	CDK4	S1041	P1042T	1042	Missense	proximal	1	no	8.778	2.252	EPSD	COSMIC	2.642	Loss
CMGC_CDK_CDK4_CDK4_ST	P43694	GATA4	P11802	CDK4	S406	P413L	413	Missense	distal	7	no	8.771	8.754	EPSD	COSMIC	2.642	Down-regulation
CMGC_CDK_CDK4_CDK4_ST	P43694	GATA4	P11802	CDK4	S406	P407R	407	Missense	proximal	1	no	8.771	1.984	EPSD	COSMIC	2.642	Loss
CMGC_CDK_CDK4_CDK4_ST	P43694	GATA4	P11802	CDK4	S406	A411V	411	Missense	distal	5	no	8.771	8.798	EPSD	COSMIC	2.642	Up-regulation
CMGC_CDK_CDK4_CDK4_ST	P43694	GATA4	P11802	CDK4	S412	Q419H	419	Missense	distal	7	no	6.893	6.891	EPSD	COSMIC	2.642	Down-regulation
CMGC_CDK_CDK4_CDK4_ST	P43694	GATA4	P11802	CDK4	S412	Q419L	419	Missense	distal	7	no	6.893	6.888	EPSD	COSMIC	2.642	Down-regulation
CMGC_CDK_CDK4_CDK4_ST	P43694	GATA4	P11802	CDK4	S412	P413L	413	Missense	proximal	1	no	6.893	-0.686	EPSD	COSMIC	2.642	Loss
CMGC_CDK_CDK4_CDK4_ST	P43694	GATA4	P11802	CDK4	S412	P407R	407	Missense	distal	-5	no	6.893	6.921	EPSD	COSMIC	2.642	Up-regulation
CMGC_CDK_CDK4_CDK4_ST	P43694	GATA4	P11802	CDK4	S412	A411V	411	Missense	proximal	-1	no	6.893	7.130	EPSD	COSMIC	2.642	Up-regulation
CMGC_CDK_CDK4_CDK4_ST	P43694	GATA4	P11802	CDK4	S415	Q419H	419	Missense	distal	4	no	4.026	4.078	EPSD	COSMIC	2.642	Up-regulation
CMGC_CDK_CDK4_CDK4_ST	P43694	GATA4	P11802	CDK4	S415	Q419L	419	Missense	distal	4	no	4.026	4.096	EPSD	COSMIC	2.642	Up-regulation
CMGC_CDK_CDK4_CDK4_ST	P43694	GATA4	P11802	CDK4	S415	P413L	413	Missense	proximal	-2	no	4.026	3.497	EPSD	COSMIC	2.642	Down-regulation
CMGC_CDK_CDK4_CDK4_ST	P43694	GATA4	P11802	CDK4	S415	A411V	411	Missense	distal	-4	no	4.026	4.027	EPSD	COSMIC	2.642	Up-regulation
CMGC_CDK_CDK4_CDK4_ST	P43694	GATA4	P11802	CDK4	S417	Q419H	419	Missense	proximal	2	no	7.482	7.464	EPSD	COSMIC	2.642	Down-regulation
CMGC_CDK_CDK4_CDK4_ST	P43694	GATA4	P11802	CDK4	S417	Q419L	419	Missense	proximal	2	no	7.482	7.484	EPSD	COSMIC	2.642	Up-regulation
CMGC_CDK_CDK4_CDK4_ST	P43694	GATA4	P11802	CDK4	S417	P413L	413	Missense	distal	-4	no	7.482	7.483	EPSD	COSMIC	2.642	Up-regulation
CMGC_CDK_CDK4_CDK4_ST	P43694	GATA4	P11802	CDK4	S417	A411V	411	Missense	distal	-6	no	7.482	7.737	EPSD	COSMIC	2.642	Up-regulation
CMGC_CDK_CDK4_CDK4_ST	P43694	GATA4	P11802	CDK4	S417	Q424K	424	Missense	distal	7	no	7.482	7.489	EPSD	COSMIC	2.642	Up-regulation
CMGC_CDK_CDK4_CDK4_ST	O43791	SPOP	P11802	CDK4	S6	P9F	9	Missense	distal	3	no	8.610	7.714	PhosphoSitePlus	COSMIC	2.642	Down-regulation
CMGC_CDK_CDK4_CDK4_ST	Q9NS23	RASSF1	P11802	CDK4	S183	P181S	181	Missense	proximal	-2	no	3.314	3.009	EPSD	COSMIC;GDSC;CCLE	2.642	Down-regulation
CMGC_CDK_CDK4_CDK4_ST	Q9NS23	RASSF1	P11802	CDK4	S183	P177S	177	Missense	distal	-6	no	3.314	3.105	EPSD	COSMIC	2.642	Down-regulation
CMGC_CDK_CDK4_CDK4_ST	Q9NS23	RASSF1	P11802	CDK4	S183	S179R	179	Missense	distal	-4	no	3.314	3.315	EPSD	COSMIC	2.642	Up-regulation
CMGC_CDK_CDK4_CDK4_ST	Q9NS23	RASSF1	P11802	CDK4	S183	L189Q	189	Missense	distal	6	no	3.314	3.335	EPSD	COSMIC	2.642	Up-regulation
CMGC_CDK_CDK4_CDK4_ST	Q9NS23	RASSF1	P11802	CDK4	S183	R176C	176	Missense	distal	-7	no	3.314	3.051	EPSD	COSMIC;GDSC	2.642	Down-regulation
CMGC_CDK_CDK4_CDK4_ST	Q9NS23	RASSF1	P11802	CDK4	S183	S183R	183	Missense	central	0	yes	3.314	0.000	EPSD	COSMIC	2.642	Loss
CMGC_CDK_CDK4_CDK4_ST	Q9NS23	RASSF1	P11802	CDK4	S183	R176H	176	Missense	distal	-7	no	3.314	3.166	EPSD	COSMIC	2.642	Down-regulation
CMGC_CDK_CDK4_CDK4_ST	Q9NS23	RASSF1	P11802	CDK4	S207	R205H	205	Missense	proximal	-2	no	4.882	4.847	EPSD	COSMIC;CCLE	2.642	Down-regulation
CMGC_CDK_CDK4_CDK4_ST	Q9NS23	RASSF1	P11802	CDK4	S207	T200I	200	Missense	distal	-7	no	4.882	4.648	EPSD	COSMIC	2.642	Down-regulation
STE_STE11_MEKK2_MAP3K3_ST	P08151	GLI1	Q99759	MAP3K3	S69	P66L	66	Missense	distal	-3	no	12.155	12.424	EPSD	COSMIC	11.002	Up-regulation
STE_STE11_MEKK2_MAP3K3_ST	P08151	GLI1	Q99759	MAP3K3	S69	P66R	66	Missense	distal	-3	no	12.155	11.385	EPSD	COSMIC	11.002	Down-regulation
STE_STE11_MEKK2_MAP3K3_ST	P08151	GLI1	Q99759	MAP3K3	S69	K76E	76	Missense	distal	7	no	12.155	13.140	EPSD	COSMIC	11.002	Up-regulation
STE_STE11_MEKK2_MAP3K3_ST	P08151	GLI1	Q99759	MAP3K3	S69	G65C	65	Missense	distal	-4	no	12.155	8.824	EPSD	COSMIC	11.002	Loss
STE_STE11_MEKK2_MAP3K3_ST	P08151	GLI1	Q99759	MAP3K3	S69	R72W	72	Missense	distal	3	no	12.155	12.944	EPSD	COSMIC	11.002	Up-regulation
STE_STE11_MEKK2_MAP3K3_ST	P08151	GLI1	Q99759	MAP3K3	S69	T63P	63	Missense	distal	-6	no	12.155	14.159	EPSD	COSMIC	11.002	Up-regulation
STE_STE11_MEKK2_MAP3K3_ST	P08151	GLI1	Q99759	MAP3K3	S70	T63P	63	Missense	distal	-7	no	9.840	11.620	EPSD	COSMIC	11.002	Gain
STE_STE11_MEKK2_MAP3K3_ST	P08151	GLI1	Q99759	MAP3K3	S89	S84F	84	Missense	distal	-5	no	11.297	11.263	EPSD	COSMIC	11.002	Down-regulation
STE_STE11_MEKK2_MAP3K3_ST	P08151	GLI1	Q99759	MAP3K3	S89	S92N	92	Missense	distal	3	no	11.297	11.265	EPSD	COSMIC	11.002	Down-regulation
STE_STE11_MEKK2_MAP3K3_ST	P08151	GLI1	Q99759	MAP3K3	S89	L88M	88	Missense	proximal	-1	no	11.297	9.457	EPSD	COSMIC	11.002	Loss
STE_STE11_MEKK2_MAP3K3_ST	P08151	GLI1	Q99759	MAP3K3	S89	L95M	95	Missense	distal	6	no	11.297	11.030	EPSD	COSMIC	11.002	Down-regulation
STE_STE11_MEKK2_MAP3K3_ST	P08151	GLI1	Q99759	MAP3K3	S201	P194L	194	Missense	distal	-7	no	29.891	29.868	PhosphoSitePlus;EPSD	COSMIC	11.002	Down-regulation
STE_STE11_MEKK2_MAP3K3_ST	P08151	GLI1	Q99759	MAP3K3	S201	M199V	199	Missense	proximal	-2	no	29.891	30.096	PhosphoSitePlus;EPSD	COSMIC	11.002	Up-regulation
STE_STE11_MEKK2_MAP3K3_ST	P08151	GLI1	Q99759	MAP3K3	S201	P194R	194	Missense	distal	-7	no	29.891	29.318	PhosphoSitePlus;EPSD	COSMIC	11.002	Down-regulation
STE_STE11_MEKK2_MAP3K3_ST	P08151	GLI1	Q99759	MAP3K3	S201	Q208L	208	Missense	distal	7	no	29.891	30.092	PhosphoSitePlus;EPSD	COSMIC;GDSC	11.002	Up-regulation
STE_STE11_MEKK2_MAP3K3_ST	P08151	GLI1	Q99759	MAP3K3	S201	D198Y	198	Missense	distal	-3	no	29.891	28.303	PhosphoSitePlus;EPSD	COSMIC	11.002	Down-regulation
STE_STE11_MEKK2_MAP3K3_ST	P08151	GLI1	Q99759	MAP3K3	S201	Q208R	208	Missense	distal	7	no	29.891	29.856	PhosphoSitePlus;EPSD	COSMIC	11.002	Down-regulation
STE_STE11_MEKK2_MAP3K3_ST	P08151	GLI1	Q99759	MAP3K3	S201	G197A	197	Missense	distal	-4	no	29.891	25.273	PhosphoSitePlus;EPSD	COSMIC	11.002	Down-regulation
STE_STE11_MEKK2_MAP3K3_ST	P08151	GLI1	Q99759	MAP3K3	S204	L211M	211	Missense	distal	7	no	28.536	28.459	EPSD;PhosphoSitePlus	COSMIC	11.002	Down-regulation
STE_STE11_MEKK2_MAP3K3_ST	P08151	GLI1	Q99759	MAP3K3	S204	P210A	210	Missense	distal	6	no	28.536	28.503	EPSD;PhosphoSitePlus	COSMIC	11.002	Down-regulation
STE_STE11_MEKK2_MAP3K3_ST	P08151	GLI1	Q99759	MAP3K3	S204	M199V	199	Missense	distal	-5	no	28.536	27.943	EPSD;PhosphoSitePlus	COSMIC	11.002	Down-regulation
STE_STE11_MEKK2_MAP3K3_ST	P08151	GLI1	Q99759	MAP3K3	S204	Q208L	208	Missense	distal	4	no	28.536	26.596	EPSD;PhosphoSitePlus	COSMIC;GDSC	11.002	Down-regulation
STE_STE11_MEKK2_MAP3K3_ST	P08151	GLI1	Q99759	MAP3K3	S204	D198Y	198	Missense	distal	-6	no	28.536	27.852	EPSD;PhosphoSitePlus	COSMIC	11.002	Down-regulation
STE_STE11_MEKK2_MAP3K3_ST	P08151	GLI1	Q99759	MAP3K3	S204	Q208R	208	Missense	distal	4	no	28.536	25.802	EPSD;PhosphoSitePlus	COSMIC	11.002	Down-regulation
STE_STE11_MEKK2_MAP3K3_ST	P08151	GLI1	Q99759	MAP3K3	S204	G197A	197	Missense	distal	-7	no	28.536	28.415	EPSD;PhosphoSitePlus	COSMIC	11.002	Down-regulation
STE_STE11_MEKK2_MAP3K3_ST	P08151	GLI1	Q99759	MAP3K3	S243	D247Y	247	Missense	distal	4	no	28.806	29.671	EPSD;PhosphoSitePlus	COSMIC	11.002	Up-regulation
STE_STE11_MEKK2_MAP3K3_ST	P08151	GLI1	Q99759	MAP3K3	S243	D247N	247	Missense	distal	4	no	28.806	28.993	EPSD;PhosphoSitePlus	COSMIC	11.002	Up-regulation
STE_STE11_MEKK2_MAP3K3_ST	P08151	GLI1	Q99759	MAP3K3	S243	Q244H	244	Missense	proximal	1	no	28.806	27.286	EPSD;PhosphoSitePlus	COSMIC	11.002	Down-regulation
STE_STE11_MEKK2_MAP3K3_ST	P08151	GLI1	Q99759	MAP3K3	S243	D240G	240	Missense	distal	-3	no	28.806	27.949	EPSD;PhosphoSitePlus	COSMIC	11.002	Down-regulation
STE_STE11_MEKK2_MAP3K3_ST	P08151	GLI1	Q99759	MAP3K3	T527	G534A	534	Missense	distal	7	no	9.774	11.055	EPSD	COSMIC	11.002	Gain
STE_STE11_MEKK2_MAP3K3_ST	P08151	GLI1	Q99759	MAP3K3	S560	L561M	561	Missense	proximal	1	no	9.857	11.058	EPSD	COSMIC	11.002	Gain
STE_STE11_MEKK2_MAP3K3_ST	P08151	GLI1	Q99759	MAP3K3	S937	A941T	941	Missense	distal	4	no	10.150	13.559	EPSD	COSMIC	11.002	Gain
STE_STE11_MEKK2_MAP3K3_ST	P08151	GLI1	Q99759	MAP3K3	S968	E972Q	972	Missense	distal	4	no	28.505	29.762	EPSD;PhosphoSitePlus	COSMIC;GDSC;CCLE	11.002	Up-regulation
STE_STE11_MEKK2_MAP3K3_ST	P08151	GLI1	Q99759	MAP3K3	S968	C970S	970	Missense	proximal	2	no	28.505	26.788	EPSD;PhosphoSitePlus	COSMIC	11.002	Down-regulation
STE_STE11_MEKK2_MAP3K3_ST	P08151	GLI1	Q99759	MAP3K3	S1071	R1068Q	1068	Missense	distal	-3	no	11.291	10.493	EPSD	COSMIC	11.002	Loss
STE_STE11_MEKK2_MAP3K3_ST	P08151	GLI1	Q99759	MAP3K3	S1071	R1068W	1068	Missense	distal	-3	no	11.291	11.431	EPSD	COSMIC	11.002	Up-regulation
STE_STE11_MEKK2_MAP3K3_ST	P08151	GLI1	Q99759	MAP3K3	S1071	H1065N	1065	Missense	distal	-6	no	11.291	10.328	EPSD	COSMIC	11.002	Loss
STE_STE11_MEKK2_MAP3K3_ST	P08151	GLI1	Q99759	MAP3K3	S1071	S1064P	1064	Missense	distal	-7	no	11.291	11.911	EPSD	COSMIC	11.002	Up-regulation
STE_STE11_MEKK2_MAP3K3_ST	P08151	GLI1	Q99759	MAP3K3	S1071	P1077H	1077	Missense	distal	6	no	11.291	11.454	EPSD	COSMIC	11.002	Up-regulation
STE_STE11_MEKK2_MAP3K3_ST	P08151	GLI1	Q99759	MAP3K3	T1074	R1068Q	1068	Missense	distal	-6	no	30.679	30.249	EPSD;PhosphoSitePlus	COSMIC	11.002	Down-regulation
STE_STE11_MEKK2_MAP3K3_ST	P08151	GLI1	Q99759	MAP3K3	T1074	R1068W	1068	Missense	distal	-6	no	30.679	31.289	EPSD;PhosphoSitePlus	COSMIC	11.002	Up-regulation
STE_STE11_MEKK2_MAP3K3_ST	P08151	GLI1	Q99759	MAP3K3	T1074	P1077H	1077	Missense	distal	3	no	30.679	32.429	EPSD;PhosphoSitePlus	COSMIC	11.002	Up-regulation
STE_STE11_MEKK2_MAP3K3_ST	P08151	GLI1	Q99759	MAP3K3	S1078	N1082D	1082	Missense	distal	4	no	28.527	28.339	EPSD;PhosphoSitePlus	COSMIC	11.002	Down-regulation
STE_STE11_MEKK2_MAP3K3_ST	P08151	GLI1	Q99759	MAP3K3	S1078	P1077H	1077	Missense	proximal	-1	no	28.527	28.920	EPSD;PhosphoSitePlus	COSMIC	11.002	Up-regulation
STE_STE11_MEKK2_MAP3K3_ST	P53805	RCAN1	Q99759	MAP3K3	S163	P169L	169	Missense	distal	6	no	28.012	28.296	PhosphoSitePlus;EPSD	COSMIC	11.002	Up-regulation
STE_STE11_MEKK2_MAP3K3_ST	P53805	RCAN1	Q99759	MAP3K3	S163	P168L	168	Missense	distal	5	no	28.012	29.408	PhosphoSitePlus;EPSD	COSMIC	11.002	Up-regulation
STE_STE11_MEKK2_MAP3K3_ST	P53805	RCAN1	Q99759	MAP3K3	S163	P165L	165	Missense	proximal	2	no	28.012	25.748	PhosphoSitePlus;EPSD	COSMIC	11.002	Down-regulation
STE_STE11_MEKK2_MAP3K3_ST	P53805	RCAN1	Q99759	MAP3K3	S167	P169L	169	Missense	proximal	2	no	29.082	26.818	EPSD;PhosphoSitePlus	COSMIC	11.002	Down-regulation
STE_STE11_MEKK2_MAP3K3_ST	P53805	RCAN1	Q99759	MAP3K3	S167	P168L	168	Missense	proximal	1	no	29.082	24.680	EPSD;PhosphoSitePlus	COSMIC	11.002	Down-regulation
STE_STE11_MEKK2_MAP3K3_ST	P53805	RCAN1	Q99759	MAP3K3	S167	P165L	165	Missense	proximal	-2	no	29.082	28.120	EPSD;PhosphoSitePlus	COSMIC	11.002	Down-regulation
STE_STE11_MEKK2_MAP3K3_ST	P53805	RCAN1	Q99759	MAP3K3	T179	L186Q	186	Missense	distal	7	no	11.802	11.601	EPSD	COSMIC	11.002	Down-regulation
STE_STE11_MEKK2_MAP3K3_ST	P53805	RCAN1	Q99759	MAP3K3	T179	N183K	183	Missense	distal	4	no	11.802	10.002	EPSD	COSMIC	11.002	Loss
STE_STE11_MEKK2_MAP3K3_ST	P53805	RCAN1	Q99759	MAP3K3	T247	P244L	244	Missense	distal	-3	no	12.331	12.600	EPSD	COSMIC	11.002	Up-regulation
STE_STE11_MEKK2_MAP3K3_ST	P53805	RCAN1	Q99759	MAP3K3	T247	R243K	243	Missense	distal	-4	no	12.331	12.341	EPSD	COSMIC;GDSC;CCLE	11.002	Up-regulation
STE_STE11_MEKK2_MAP3K3_ST	P53805	RCAN1	Q99759	MAP3K3	T247	T247M	247	Missense	central	0	yes	12.331	0.000	EPSD	COSMIC;GDSC;CCLE	11.002	Loss
TKL_STKR_STKR1_TGFBR1_ST	Q03167	TGFBR3	P36897	TGFBR1	S322	D319G	319	Missense	distal	-3	no	16.194	16.202	EPSD	COSMIC	13.873	Up-regulation
TKL_STKR_STKR1_TGFBR1_ST	Q03167	TGFBR3	P36897	TGFBR1	S322	N326S	326	Missense	distal	4	no	16.194	16.201	EPSD	COSMIC	13.873	Up-regulation
TKL_STKR_STKR1_TGFBR1_ST	Q03167	TGFBR3	P36897	TGFBR1	S651	P647L	647	Missense	distal	-4	no	14.135	13.630	EPSD	COSMIC	13.873	Loss
TKL_STKR_STKR1_TGFBR1_ST	Q03167	TGFBR3	P36897	TGFBR1	S651	D648N	648	Missense	distal	-3	no	14.135	13.755	EPSD	COSMIC	13.873	Loss
TKL_STKR_STKR1_TGFBR1_ST	Q03167	TGFBR3	P36897	TGFBR1	S831	G838S	838	Missense	distal	7	no	13.839	14.957	PhosphoSitePlus	COSMIC;CCLE	13.873	Gain
TKL_STKR_STKR1_TGFBR1_ST	Q15796	SMAD2	P36897	TGFBR1	S47	K53E	53	Missense	distal	6	no	13.996	14.983	EPSD	COSMIC	13.873	Up-regulation
TKL_STKR_STKR1_TGFBR1_ST	Q15796	SMAD2	P36897	TGFBR1	S47	W40G	40	Missense	distal	-7	no	13.996	14.721	EPSD	COSMIC	13.873	Up-regulation
TKL_STKR_STKR1_TGFBR1_ST	Q15796	SMAD2	P36897	TGFBR1	S47	A44T	44	Missense	distal	-3	no	13.996	13.733	EPSD	COSMIC	13.873	Loss
TKL_STKR_STKR1_TGFBR1_ST	Q15796	SMAD2	P36897	TGFBR1	S47	K54T	54	Missense	distal	7	no	13.996	14.073	EPSD	COSMIC	13.873	Up-regulation
TKL_STKR_STKR1_TGFBR1_ST	Q15796	SMAD2	P36897	TGFBR1	S47	E42Q	42	Missense	distal	-5	no	13.996	13.677	EPSD	COSMIC	13.873	Loss
TKL_STKR_STKR1_TGFBR1_ST	Q15796	SMAD2	P36897	TGFBR1	S110	R114C	114	Missense	distal	4	no	13.969	14.036	EPSD	COSMIC	13.873	Up-regulation
TKL_STKR_STKR1_TGFBR1_ST	Q15796	SMAD2	P36897	TGFBR1	S118	R114C	114	Missense	distal	-4	no	16.204	16.247	EPSD	COSMIC	13.873	Up-regulation
TKL_STKR_STKR1_TGFBR1_ST	Q15796	SMAD2	P36897	TGFBR1	S118	H125R	125	Missense	distal	7	no	16.204	16.796	EPSD	COSMIC	13.873	Up-regulation
TKL_STKR_STKR1_TGFBR1_ST	Q15796	SMAD2	P36897	TGFBR1	S118	G122R	122	Missense	distal	4	no	16.204	16.113	EPSD	COSMIC	13.873	Down-regulation
TKL_STKR_STKR1_TGFBR1_ST	Q15796	SMAD2	P36897	TGFBR1	S118	S118F	118	Missense	central	0	yes	16.204	0.000	EPSD	COSMIC	13.873	Loss
TKL_STKR_STKR1_TGFBR1_ST	Q15796	SMAD2	P36897	TGFBR1	S118	H119L	119	Missense	proximal	1	no	16.204	16.158	EPSD	COSMIC	13.873	Down-regulation
TKL_STKR_STKR1_TGFBR1_ST	Q15796	SMAD2	P36897	TGFBR1	T220	T220M	220	Missense	central	0	yes	13.948	0.000	EPSD	COSMIC;GDSC;CCLE	13.873	Loss
TKL_STKR_STKR1_TGFBR1_ST	Q15796	SMAD2	P36897	TGFBR1	T220	E219K	219	Missense	proximal	-1	no	13.948	13.870	EPSD	COSMIC	13.873	Loss
TKL_STKR_STKR1_TGFBR1_ST	Q15796	SMAD2	P36897	TGFBR1	T220	P218L	218	Missense	proximal	-2	no	13.948	14.151	EPSD	COSMIC	13.873	Up-regulation
TKL_STKR_STKR1_TGFBR1_ST	Q15796	SMAD2	P36897	TGFBR1	T220	T220A	220	Missense	central	0	yes	13.948	0.000	EPSD	COSMIC	13.873	Loss
TKL_STKR_STKR1_TGFBR1_ST	Q15796	SMAD2	P36897	TGFBR1	T220	P221S	221	Missense	proximal	1	no	13.948	13.907	EPSD	COSMIC	13.873	Down-regulation
TKL_STKR_STKR1_TGFBR1_ST	Q15796	SMAD2	P36897	TGFBR1	T220	P218S	218	Missense	proximal	-2	no	13.948	14.634	EPSD	COSMIC	13.873	Up-regulation
TKL_STKR_STKR1_TGFBR1_ST	Q15796	SMAD2	P36897	TGFBR1	T220	Q213H	213	Missense	distal	-7	no	13.948	11.851	EPSD	COSMIC	13.873	Loss
TKL_STKR_STKR1_TGFBR1_ST	Q15796	SMAD2	P36897	TGFBR1	T220	P223S	223	Missense	distal	3	no	13.948	13.173	EPSD	COSMIC	13.873	Loss
TKL_STKR_STKR1_TGFBR1_ST	Q15796	SMAD2	P36897	TGFBR1	S250	S255F	255	Missense	distal	5	no	15.150	16.182	EPSD	COSMIC	13.873	Up-regulation
TKL_STKR_STKR1_TGFBR1_ST	Q15796	SMAD2	P36897	TGFBR1	S250	L249V	249	Missense	proximal	-1	no	15.150	13.951	EPSD	COSMIC	13.873	Down-regulation
TKL_STKR_STKR1_TGFBR1_ST	Q15796	SMAD2	P36897	TGFBR1	S250	E248Q	248	Missense	proximal	-2	no	15.150	15.536	EPSD	COSMIC	13.873	Up-regulation
TKL_STKR_STKR1_TGFBR1_ST	Q15796	SMAD2	P36897	TGFBR1	S250	S245C	245	Missense	distal	-5	no	15.150	14.363	EPSD	COSMIC	13.873	Down-regulation
TKL_STKR_STKR1_TGFBR1_ST	Q15796	SMAD2	P36897	TGFBR1	S250	P246L	246	Missense	distal	-4	no	15.150	14.645	EPSD	COSMIC	13.873	Down-regulation
TKL_STKR_STKR1_TGFBR1_ST	Q15796	SMAD2	P36897	TGFBR1	S260	S255F	255	Missense	distal	-5	no	14.690	14.730	EPSD	COSMIC	13.873	Up-regulation
TKL_STKR_STKR1_TGFBR1_ST	Q15796	SMAD2	P36897	TGFBR1	S260	P265H	265	Missense	distal	5	no	14.690	15.008	EPSD	COSMIC	13.873	Up-regulation
TKL_STKR_STKR1_TGFBR1_ST	Q15796	SMAD2	P36897	TGFBR1	S260	Q264E	264	Missense	distal	4	no	14.690	14.756	EPSD	COSMIC	13.873	Up-regulation
TKL_STKR_STKR1_TGFBR1_ST	Q15796	SMAD2	P36897	TGFBR1	S464	R462C	462	Missense	proximal	-2	no	17.945	17.883	EPSD;PhosphoSitePlus	COSMIC;GDSC;CCLE	13.873	Down-regulation
TKL_STKR_STKR1_TGFBR1_ST	Q15796	SMAD2	P36897	TGFBR1	S464	C463F	463	Missense	proximal	-1	no	17.945	17.680	EPSD;PhosphoSitePlus	COSMIC	13.873	Down-regulation
TKL_STKR_STKR1_TGFBR1_ST	Q15796	SMAD2	P36897	TGFBR1	S464	G457R	457	Missense	distal	-7	no	17.945	17.494	EPSD;PhosphoSitePlus	COSMIC	13.873	Down-regulation
TKL_STKR_STKR1_TGFBR1_ST	Q15796	SMAD2	P36897	TGFBR1	S464	S465I	465	Missense	proximal	1	no	17.945	18.087	EPSD;PhosphoSitePlus	COSMIC	13.873	Up-regulation
TKL_STKR_STKR1_TGFBR1_ST	Q15796	SMAD2	P36897	TGFBR1	S464	C463Y	463	Missense	proximal	-1	no	17.945	17.232	EPSD;PhosphoSitePlus	COSMIC	13.873	Down-regulation
TKL_STKR_STKR1_TGFBR1_ST	Q15796	SMAD2	P36897	TGFBR1	S464	S465N	465	Missense	proximal	1	no	17.945	18.088	EPSD;PhosphoSitePlus	COSMIC;GDSC;CCLE	13.873	Up-regulation
TKL_STKR_STKR1_TGFBR1_ST	Q15796	SMAD2	P36897	TGFBR1	S464	P459H	459	Missense	distal	-5	no	17.945	18.587	EPSD;PhosphoSitePlus	COSMIC	13.873	Up-regulation
TKL_STKR_STKR1_TGFBR1_ST	Q15796	SMAD2	P36897	TGFBR1	S464	S465R	465	Missense	proximal	1	no	17.945	18.085	EPSD;PhosphoSitePlus	COSMIC	13.873	Up-regulation
TKL_STKR_STKR1_TGFBR1_ST	Q15796	SMAD2	P36897	TGFBR1	S464	S464L	464	Missense	central	0	yes	17.945	0.000	EPSD;PhosphoSitePlus	COSMIC	13.873	Loss
TKL_STKR_STKR1_TGFBR1_ST	Q15796	SMAD2	P36897	TGFBR1	S465	R462C	462	Missense	distal	-3	no	17.513	17.234	PhosphoSitePlus;EPSD	COSMIC;GDSC;CCLE	13.873	Down-regulation
TKL_STKR_STKR1_TGFBR1_ST	Q15796	SMAD2	P36897	TGFBR1	S465	C463F	463	Missense	proximal	-2	no	17.513	17.577	PhosphoSitePlus;EPSD	COSMIC	13.873	Up-regulation
TKL_STKR_STKR1_TGFBR1_ST	Q15796	SMAD2	P36897	TGFBR1	S465	S465I	465	Missense	central	0	yes	17.513	0.000	PhosphoSitePlus;EPSD	COSMIC	13.873	Loss
TKL_STKR_STKR1_TGFBR1_ST	Q15796	SMAD2	P36897	TGFBR1	S465	C463Y	463	Missense	proximal	-2	no	17.513	17.621	PhosphoSitePlus;EPSD	COSMIC	13.873	Up-regulation
TKL_STKR_STKR1_TGFBR1_ST	Q15796	SMAD2	P36897	TGFBR1	S465	S465N	465	Missense	central	0	yes	17.513	0.000	PhosphoSitePlus;EPSD	COSMIC;GDSC;CCLE	13.873	Loss
TKL_STKR_STKR1_TGFBR1_ST	Q15796	SMAD2	P36897	TGFBR1	S465	P459H	459	Missense	distal	-6	no	17.513	17.535	PhosphoSitePlus;EPSD	COSMIC	13.873	Up-regulation
TKL_STKR_STKR1_TGFBR1_ST	Q15796	SMAD2	P36897	TGFBR1	S465	S465R	465	Missense	central	0	yes	17.513	0.000	PhosphoSitePlus;EPSD	COSMIC	13.873	Loss
TKL_STKR_STKR1_TGFBR1_ST	Q15796	SMAD2	P36897	TGFBR1	S465	S464L	464	Missense	proximal	-1	no	17.513	19.880	PhosphoSitePlus;EPSD	COSMIC	13.873	Up-regulation
TKL_STKR_STKR1_TGFBR1_ST	Q15796	SMAD2	P36897	TGFBR1	S467	R462C	462	Missense	distal	-5	no	19.526	18.255	EPSD;PhosphoSitePlus	COSMIC;GDSC;CCLE	13.873	Down-regulation
TKL_STKR_STKR1_TGFBR1_ST	Q15796	SMAD2	P36897	TGFBR1	S467	C463F	463	Missense	distal	-4	no	19.526	19.467	EPSD;PhosphoSitePlus	COSMIC	13.873	Down-regulation
TKL_STKR_STKR1_TGFBR1_ST	Q15796	SMAD2	P36897	TGFBR1	S467	S465I	465	Missense	proximal	-2	no	19.526	18.810	EPSD;PhosphoSitePlus	COSMIC	13.873	Down-regulation
TKL_STKR_STKR1_TGFBR1_ST	Q15796	SMAD2	P36897	TGFBR1	S467	C463Y	463	Missense	distal	-4	no	19.526	19.308	EPSD;PhosphoSitePlus	COSMIC	13.873	Down-regulation
TKL_STKR_STKR1_TGFBR1_ST	Q15796	SMAD2	P36897	TGFBR1	S467	S465N	465	Missense	proximal	-2	no	19.526	18.994	EPSD;PhosphoSitePlus	COSMIC;GDSC;CCLE	13.873	Down-regulation
TKL_STKR_STKR1_TGFBR1_ST	Q15796	SMAD2	P36897	TGFBR1	S467	S465R	465	Missense	proximal	-2	no	19.526	18.919	EPSD;PhosphoSitePlus	COSMIC	13.873	Down-regulation
TKL_STKR_STKR1_TGFBR1_ST	Q15796	SMAD2	P36897	TGFBR1	S467	S464L	464	Missense	distal	-3	no	19.526	18.823	EPSD;PhosphoSitePlus	COSMIC	13.873	Down-regulation
TKL_STKR_STKR1_TGFBR1_ST	P68104	EEF1A1	P36897	TGFBR1	S175	V174I	174	Missense	proximal	-1	no	14.008	14.979	EPSD	COSMIC	13.873	Up-regulation
TKL_STKR_STKR1_TGFBR1_ST	P68104	EEF1A1	P36897	TGFBR1	S300	N307T	307	Missense	distal	7	no	29.072	28.959	PhosphoSitePlus	COSMIC	13.873	Down-regulation
TKL_STKR_STKR1_TGFBR1_ST	P68104	EEF1A1	P36897	TGFBR1	S300	G305V	305	Missense	distal	5	no	29.072	28.989	PhosphoSitePlus	COSMIC	13.873	Down-regulation
TKL_STKR_STKR1_TGFBR1_ST	P68104	EEF1A1	P36897	TGFBR1	S354	N348K	348	Missense	distal	-6	no	15.279	15.045	EPSD	COSMIC	13.873	Down-regulation
TKL_STKR_STKR1_TGFBR1_ST	P68104	EEF1A1	P36897	TGFBR1	S354	S354N	354	Missense	central	0	yes	15.279	0.000	EPSD	COSMIC	13.873	Loss
TKL_STKR_STKR1_TGFBR1_ST	Q9H3D4	TP63	P36897	TGFBR1	S43	Q42E	42	Missense	proximal	-1	no	13.245	14.210	EPSD	COSMIC	13.873	Gain
TKL_STKR_STKR1_TGFBR1_ST	Q9H3D4	TP63	P36897	TGFBR1	S160	P161S	161	Missense	proximal	1	no	29.350	29.310	EPSD	COSMIC	13.873	Down-regulation
TKL_STKR_STKR1_TGFBR1_ST	Q9H3D4	TP63	P36897	TGFBR1	S160	L159F	159	Missense	proximal	-1	no	29.350	28.881	EPSD	COSMIC	13.873	Down-regulation
TKL_STKR_STKR1_TGFBR1_ST	Q9H3D4	TP63	P36897	TGFBR1	S160	S160C	160	Missense	central	0	yes	29.350	0.000	EPSD	COSMIC	13.873	Loss
TKL_STKR_STKR1_TGFBR1_ST	Q9H3D4	TP63	P36897	TGFBR1	S160	S154C	154	Missense	distal	-6	no	29.350	29.801	EPSD	COSMIC;CCLE	13.873	Up-regulation
TKL_STKR_STKR1_TGFBR1_ST	Q9H3D4	TP63	P36897	TGFBR1	S160	S153I	153	Missense	distal	-7	no	29.350	25.618	EPSD	COSMIC	13.873	Down-regulation
TKL_STKR_STKR1_TGFBR1_ST	Q9H3D4	TP63	P36897	TGFBR1	S160	P166H	166	Missense	distal	6	no	29.350	29.940	EPSD	COSMIC	13.873	Up-regulation
TKL_STKR_STKR1_TGFBR1_ST	Q9H3D4	TP63	P36897	TGFBR1	S160	P161L	161	Missense	proximal	1	no	29.350	29.380	EPSD	COSMIC	13.873	Up-regulation
TKL_STKR_STKR1_TGFBR1_ST	Q9H3D4	TP63	P36897	TGFBR1	S162	T169N	169	Missense	distal	7	no	28.456	28.570	EPSD	COSMIC	13.873	Up-regulation
TKL_STKR_STKR1_TGFBR1_ST	Q9H3D4	TP63	P36897	TGFBR1	S162	P161S	161	Missense	proximal	-1	no	28.456	26.850	EPSD	COSMIC	13.873	Down-regulation
TKL_STKR_STKR1_TGFBR1_ST	Q9H3D4	TP63	P36897	TGFBR1	S162	L159F	159	Missense	distal	-3	no	28.456	28.151	EPSD	COSMIC	13.873	Down-regulation
TKL_STKR_STKR1_TGFBR1_ST	Q9H3D4	TP63	P36897	TGFBR1	S162	S160C	160	Missense	proximal	-2	no	28.456	27.787	EPSD	COSMIC	13.873	Down-regulation
TKL_STKR_STKR1_TGFBR1_ST	Q9H3D4	TP63	P36897	TGFBR1	S162	T169I	169	Missense	distal	7	no	28.456	27.430	EPSD	COSMIC	13.873	Down-regulation
TKL_STKR_STKR1_TGFBR1_ST	Q9H3D4	TP63	P36897	TGFBR1	S162	P166H	166	Missense	distal	4	no	28.456	28.551	EPSD	COSMIC	13.873	Up-regulation
TKL_STKR_STKR1_TGFBR1_ST	Q9H3D4	TP63	P36897	TGFBR1	S162	N168S	168	Missense	distal	6	no	28.456	27.959	EPSD	COSMIC	13.873	Down-regulation
TKL_STKR_STKR1_TGFBR1_ST	Q9H3D4	TP63	P36897	TGFBR1	S162	P161L	161	Missense	proximal	-1	no	28.456	29.217	EPSD	COSMIC	13.873	Up-regulation
TKL_STKR_STKR1_TGFBR1_ST	Q9H3D4	TP63	P36897	TGFBR1	S358	Q363H	363	Missense	distal	5	no	13.095	14.057	EPSD	COSMIC	13.873	Gain
TKL_STKR_STKR1_TGFBR1_ST	Q9H3D4	TP63	P36897	TGFBR1	S358	V364I	364	Missense	distal	6	no	13.095	15.514	EPSD	COSMIC;GDSC;CCLE	13.873	Gain
TKL_STKR_STKR1_TGFBR1_ST	Q9H3D4	TP63	P36897	TGFBR1	S367	Q362H	362	Missense	distal	-5	no	15.787	16.345	EPSD	COSMIC	13.873	Up-regulation
TKL_STKR_STKR1_TGFBR1_ST	Q9H3D4	TP63	P36897	TGFBR1	S367	D366N	366	Missense	proximal	-1	no	15.787	16.358	EPSD	COSMIC	13.873	Up-regulation
TKL_STKR_STKR1_TGFBR1_ST	Q9H3D4	TP63	P36897	TGFBR1	S367	K369M	369	Missense	proximal	2	no	15.787	15.805	EPSD	COSMIC	13.873	Up-regulation
TKL_STKR_STKR1_TGFBR1_ST	Q9H3D4	TP63	P36897	TGFBR1	S367	D366G	366	Missense	proximal	-1	no	15.787	14.858	EPSD	COSMIC	13.873	Down-regulation
TKL_STKR_STKR1_TGFBR1_ST	Q9H3D4	TP63	P36897	TGFBR1	S367	R360T	360	Missense	distal	-7	no	15.787	16.084	EPSD	COSMIC	13.873	Up-regulation
TKL_STKR_STKR1_TGFBR1_ST	Q9H3D4	TP63	P36897	TGFBR1	S367	T374M	374	Missense	distal	7	no	15.787	15.353	EPSD	COSMIC	13.873	Down-regulation
TKL_STKR_STKR1_TGFBR1_ST	Q9H3D4	TP63	P36897	TGFBR1	S367	K369R	369	Missense	proximal	2	no	15.787	15.809	EPSD	COSMIC	13.873	Up-regulation
TKL_STKR_STKR1_TGFBR1_ST	Q9H3D4	TP63	P36897	TGFBR1	S367	Q363H	363	Missense	distal	-4	no	15.787	15.400	EPSD	COSMIC	13.873	Down-regulation
TKL_STKR_STKR1_TGFBR1_ST	Q9H3D4	TP63	P36897	TGFBR1	S367	D372H	372	Missense	distal	5	no	15.787	15.406	EPSD	COSMIC	13.873	Down-regulation
TKL_STKR_STKR1_TGFBR1_ST	Q9H3D4	TP63	P36897	TGFBR1	S367	V364I	364	Missense	distal	-3	no	15.787	15.467	EPSD	COSMIC;GDSC;CCLE	13.873	Down-regulation
TKL_STKR_STKR1_TGFBR1_ST	Q9H3D4	TP63	P36897	TGFBR1	S455	S462L	462	Missense	distal	7	no	14.980	13.691	EPSD	COSMIC	13.873	Loss
TKL_STKR_STKR1_TGFBR1_ST	Q9H3D4	TP63	P36897	TGFBR1	S455	S462A	462	Missense	distal	7	no	14.980	14.294	EPSD	COSMIC	13.873	Down-regulation
TKL_STKR_STKR1_TGFBR1_ST	Q9H3D4	TP63	P36897	TGFBR1	S455	Q454H	454	Missense	proximal	-1	no	14.980	15.973	EPSD	COSMIC	13.873	Up-regulation
TKL_STKR_STKR1_TGFBR1_ST	Q9H3D4	TP63	P36897	TGFBR1	S455	Q454R	454	Missense	proximal	-1	no	14.980	16.152	EPSD	COSMIC	13.873	Up-regulation
TKL_STKR_STKR1_TGFBR1_ST	Q9H3D4	TP63	P36897	TGFBR1	S455	Q450R	450	Missense	distal	-5	no	14.980	15.936	EPSD	COSMIC	13.873	Up-regulation
TKL_STKR_STKR1_TGFBR1_ST	Q9H3D4	TP63	P36897	TGFBR1	S455	Q450H	450	Missense	distal	-5	no	14.980	15.538	EPSD	COSMIC	13.873	Up-regulation
TKL_STKR_STKR1_TGFBR1_ST	Q9H3D4	TP63	P36897	TGFBR1	S455	S457G	457	Missense	proximal	2	no	14.980	14.715	EPSD	COSMIC	13.873	Down-regulation
TKL_STKR_STKR1_TGFBR1_ST	Q9H3D4	TP63	P36897	TGFBR1	S457	S462L	462	Missense	distal	5	no	15.283	15.805	EPSD	COSMIC	13.873	Up-regulation
TKL_STKR_STKR1_TGFBR1_ST	Q9H3D4	TP63	P36897	TGFBR1	S457	S462A	462	Missense	distal	5	no	15.283	15.556	EPSD	COSMIC	13.873	Up-regulation
TKL_STKR_STKR1_TGFBR1_ST	Q9H3D4	TP63	P36897	TGFBR1	S457	Q454H	454	Missense	distal	-3	no	15.283	14.732	EPSD	COSMIC	13.873	Down-regulation
TKL_STKR_STKR1_TGFBR1_ST	Q9H3D4	TP63	P36897	TGFBR1	S457	S455T	455	Missense	proximal	-2	no	15.283	14.848	EPSD	COSMIC	13.873	Down-regulation
TKL_STKR_STKR1_TGFBR1_ST	Q9H3D4	TP63	P36897	TGFBR1	S457	Q454R	454	Missense	distal	-3	no	15.283	14.577	EPSD	COSMIC	13.873	Down-regulation
TKL_STKR_STKR1_TGFBR1_ST	Q9H3D4	TP63	P36897	TGFBR1	S457	Q450R	450	Missense	distal	-7	no	15.283	12.606	EPSD	COSMIC	13.873	Loss
TKL_STKR_STKR1_TGFBR1_ST	Q9H3D4	TP63	P36897	TGFBR1	S457	Q450H	450	Missense	distal	-7	no	15.283	13.186	EPSD	COSMIC	13.873	Loss
TKL_STKR_STKR1_TGFBR1_ST	Q9H3D4	TP63	P36897	TGFBR1	S457	S457G	457	Missense	central	0	yes	15.283	0.000	EPSD	COSMIC	13.873	Loss
TKL_STKR_STKR1_TGFBR1_ST	Q9H3D4	TP63	P36897	TGFBR1	S463	S462L	462	Missense	proximal	-1	no	17.273	19.640	EPSD	COSMIC	13.873	Up-regulation
TKL_STKR_STKR1_TGFBR1_ST	Q9H3D4	TP63	P36897	TGFBR1	S463	S462A	462	Missense	proximal	-1	no	17.273	18.809	EPSD	COSMIC	13.873	Up-regulation
TKL_STKR_STKR1_TGFBR1_ST	Q9H3D4	TP63	P36897	TGFBR1	S463	N467K	467	Missense	distal	4	no	17.273	17.290	EPSD	COSMIC	13.873	Up-regulation
TKL_STKR_STKR1_TGFBR1_ST	Q9H3D4	TP63	P36897	TGFBR1	S463	N470S	470	Missense	distal	7	no	17.273	18.233	EPSD	COSMIC;GDSC;CCLE	13.873	Up-regulation
TKL_STKR_STKR1_TGFBR1_ST	Q9H3D4	TP63	P36897	TGFBR1	S463	S457G	457	Missense	distal	-6	no	17.273	17.884	EPSD	COSMIC	13.873	Up-regulation
TKL_STKR_STKR1_TGFBR1_ST	Q9H3D4	TP63	P36897	TGFBR1	S621	V626F	626	Missense	distal	5	no	14.117	14.692	EPSD	COSMIC	13.873	Up-regulation
TKL_STKR_STKR1_TGFBR1_ST	Q9H3D4	TP63	P36897	TGFBR1	S621	R618W	618	Missense	distal	-3	no	14.117	13.973	EPSD	COSMIC;GDSC;CCLE	13.873	Down-regulation
TKL_STKR_STKR1_TGFBR1_ST	Q9H3D4	TP63	P36897	TGFBR1	S621	R618Q	618	Missense	distal	-3	no	14.117	14.824	EPSD	COSMIC	13.873	Up-regulation
TKL_STKR_STKR1_TGFBR1_ST	Q9H3D4	TP63	P36897	TGFBR1	S621	S622I	622	Missense	proximal	1	no	14.117	14.260	EPSD	COSMIC	13.873	Up-regulation
TKL_STKR_STKR1_TGFBR1_ST	Q9H3D4	TP63	P36897	TGFBR1	S621	H615D	615	Missense	distal	-6	no	14.117	13.951	EPSD	COSMIC	13.873	Down-regulation
TKL_STKR_STKR1_TGFBR1_ST	Q9H3D4	TP63	P36897	TGFBR1	S621	V628E	628	Missense	distal	7	no	14.117	14.189	EPSD	COSMIC	13.873	Up-regulation
TKL_STKR_STKR1_TGFBR1_ST	Q9H3D4	TP63	P36897	TGFBR1	S621	V628M	628	Missense	distal	7	no	14.117	13.865	EPSD	COSMIC	13.873	Loss
TKL_STKR_STKR1_TGFBR1_ST	Q9H3D4	TP63	P36897	TGFBR1	S621	V628A	628	Missense	distal	7	no	14.117	14.686	EPSD	COSMIC	13.873	Up-regulation
TKL_STKR_STKR1_TGFBR1_ST	P17813	ENG	P36897	TGFBR1	S619	I613M	613	Missense	distal	-6	no	15.554	15.439	EPSD	COSMIC	13.873	Down-regulation
TKL_STKR_STKR1_TGFBR1_ST	P17813	ENG	P36897	TGFBR1	S619	R623Q	623	Missense	distal	4	no	15.554	15.573	EPSD	COSMIC	13.873	Up-regulation
TKL_STKR_STKR1_TGFBR1_ST	Q96FW1	OTUB1	P36897	TGFBR1	S55	L57P	57	Missense	proximal	2	no	14.910	14.779	EPSD	COSMIC	13.873	Down-regulation
TKL_STKR_STKR1_TGFBR1_ST	Q96FW1	OTUB1	P36897	TGFBR1	S55	R51Q	51	Missense	distal	-4	no	14.910	15.153	EPSD	COSMIC	13.873	Up-regulation
CAMK_MAPKAPK_MK5_MAPKAPK5_ST	O60229	KALRN	Q8IW41	MAPKAPK5	S86	P85Q	85	Missense	proximal	-1	no	29.183	22.652	EPSD	COSMIC	23.028	Loss
CAMK_MAPKAPK_MK5_MAPKAPK5_ST	O60229	KALRN	Q8IW41	MAPKAPK5	S86	R92C	92	Missense	distal	6	no	29.183	29.094	EPSD	COSMIC	23.028	Down-regulation
CAMK_MAPKAPK_MK5_MAPKAPK5_ST	O60229	KALRN	Q8IW41	MAPKAPK5	S487	G489W	489	Missense	proximal	2	no	48.952	47.041	PhosphoSitePlus	COSMIC	23.028	Down-regulation
CAMK_MAPKAPK_MK5_MAPKAPK5_ST	O60229	KALRN	Q8IW41	MAPKAPK5	S1256	A1255T	1255	Missense	proximal	-1	no	21.767	23.050	EPSD	COSMIC	23.028	Gain
CAMK_MAPKAPK_MK5_MAPKAPK5_ST	O60229	KALRN	Q8IW41	MAPKAPK5	S1448	P1450Q	1450	Missense	proximal	2	no	24.179	28.730	EPSD	COSMIC	23.028	Up-regulation
CAMK_MAPKAPK_MK5_MAPKAPK5_ST	O60229	KALRN	Q8IW41	MAPKAPK5	S1488	R1491L	1491	Missense	distal	3	no	23.284	23.510	EPSD	COSMIC	23.028	Up-regulation
CAMK_MAPKAPK_MK5_MAPKAPK5_ST	O60229	KALRN	Q8IW41	MAPKAPK5	S1488	W1484C	1484	Missense	distal	-4	no	23.284	23.386	EPSD	COSMIC	23.028	Up-regulation
CAMK_MAPKAPK_MK5_MAPKAPK5_ST	O60229	KALRN	Q8IW41	MAPKAPK5	S1488	P1486Q	1486	Missense	proximal	-2	no	23.284	23.289	EPSD	COSMIC	23.028	Up-regulation
CAMK_MAPKAPK_MK5_MAPKAPK5_ST	O60229	KALRN	Q8IW41	MAPKAPK5	S1488	S1488P	1488	Missense	central	0	yes	23.284	0.000	EPSD	COSMIC	23.028	Loss
CAMK_MAPKAPK_MK5_MAPKAPK5_ST	O60229	KALRN	Q8IW41	MAPKAPK5	S1750	L1745M	1745	Missense	distal	-5	no	24.799	22.471	EPSD	COSMIC	23.028	Loss
CAMK_MAPKAPK_MK5_MAPKAPK5_ST	O60229	KALRN	Q8IW41	MAPKAPK5	S1750	S1757F	1757	Missense	distal	7	no	24.799	24.856	EPSD	COSMIC	23.028	Up-regulation
CAMK_MAPKAPK_MK5_MAPKAPK5_ST	O60229	KALRN	Q8IW41	MAPKAPK5	S1750	H1755Y	1755	Missense	distal	5	no	24.799	25.223	EPSD	COSMIC	23.028	Up-regulation
CAMK_MAPKAPK_MK5_MAPKAPK5_ST	O60229	KALRN	Q8IW41	MAPKAPK5	S1780	K1782N	1782	Missense	proximal	2	no	28.379	28.490	EPSD	COSMIC	23.028	Up-regulation
CAMK_MAPKAPK_MK5_MAPKAPK5_ST	O60229	KALRN	Q8IW41	MAPKAPK5	S1780	R1776H	1776	Missense	distal	-4	no	28.379	28.776	EPSD	COSMIC	23.028	Up-regulation
CAMK_MAPKAPK_MK5_MAPKAPK5_ST	O60229	KALRN	Q8IW41	MAPKAPK5	S1780	G1785E	1785	Missense	distal	5	no	28.379	34.191	EPSD	COSMIC	23.028	Up-regulation
CAMK_MAPKAPK_MK5_MAPKAPK5_ST	O60229	KALRN	Q8IW41	MAPKAPK5	S1780	R1776C	1776	Missense	distal	-4	no	28.379	28.134	EPSD	COSMIC	23.028	Down-regulation
CAMK_MAPKAPK_MK5_MAPKAPK5_ST	O60229	KALRN	Q8IW41	MAPKAPK5	S1799	G1796S	1796	Missense	distal	-3	no	18.522	26.651	EPSD	COSMIC	23.028	Gain
CAMK_MAPKAPK_MK5_MAPKAPK5_ST	O60229	KALRN	Q8IW41	MAPKAPK5	S1835	P1840Q	1840	Missense	distal	5	no	21.280	23.690	EPSD	COSMIC	23.028	Gain
CAMK_MAPKAPK_MK5_MAPKAPK5_ST	O60229	KALRN	Q8IW41	MAPKAPK5	S1835	P1840T	1840	Missense	distal	5	no	21.280	24.146	EPSD	COSMIC	23.028	Gain
CAMK_MAPKAPK_MK5_MAPKAPK5_ST	O60229	KALRN	Q8IW41	MAPKAPK5	S1856	M1855I	1855	Missense	proximal	-1	no	20.808	28.475	EPSD	COSMIC	23.028	Gain
CAMK_MAPKAPK_MK5_MAPKAPK5_ST	O60229	KALRN	Q8IW41	MAPKAPK5	S2291	P2284T	2284	Missense	distal	-7	no	28.582	28.963	EPSD	COSMIC	23.028	Up-regulation
CAMK_MAPKAPK_MK5_MAPKAPK5_ST	O60229	KALRN	Q8IW41	MAPKAPK5	S2401	K2398N	2398	Missense	distal	-3	no	23.781	28.964	EPSD	COSMIC	23.028	Up-regulation
CAMK_MAPKAPK_MK5_MAPKAPK5_ST	P25685	DNAJB1	Q8IW41	MAPKAPK5	S16	G14C	14	Missense	proximal	-2	no	31.100	30.939	EPSD	COSMIC	23.028	Down-regulation
CAMK_MAPKAPK_MK5_MAPKAPK5_ST	P25685	DNAJB1	Q8IW41	MAPKAPK5	S16	G14R	14	Missense	proximal	-2	no	31.100	31.173	EPSD	COSMIC	23.028	Up-regulation
CAMK_MAPKAPK_MK5_MAPKAPK5_ST	P25685	DNAJB1	Q8IW41	MAPKAPK5	S16	S16L	16	Missense	central	0	yes	31.100	0.000	EPSD	COSMIC	23.028	Loss
CAMK_MAPKAPK_MK5_MAPKAPK5_ST	P25685	DNAJB1	Q8IW41	MAPKAPK5	S149	N145K	145	Missense	distal	-4	no	41.858	41.798	EPSD;PhosphoSitePlus	COSMIC	23.028	Down-regulation
CAMK_MAPKAPK_MK5_MAPKAPK5_ST	P25685	DNAJB1	Q8IW41	MAPKAPK5	S149	R148H	148	Missense	proximal	-1	no	41.858	43.386	EPSD;PhosphoSitePlus	COSMIC	23.028	Up-regulation
CAMK_MAPKAPK_MK5_MAPKAPK5_ST	P25685	DNAJB1	Q8IW41	MAPKAPK5	S149	A152T	152	Missense	distal	3	no	41.858	41.805	EPSD;PhosphoSitePlus	COSMIC	23.028	Down-regulation
CAMK_MAPKAPK_MK5_MAPKAPK5_ST	P25685	DNAJB1	Q8IW41	MAPKAPK5	S149	A156V	156	Missense	distal	7	no	41.858	42.019	EPSD;PhosphoSitePlus	COSMIC	23.028	Up-regulation
CAMK_MAPKAPK_MK5_MAPKAPK5_ST	P25685	DNAJB1	Q8IW41	MAPKAPK5	S151	N145K	145	Missense	distal	-6	no	43.868	43.427	EPSD;PhosphoSitePlus	COSMIC	23.028	Down-regulation
CAMK_MAPKAPK_MK5_MAPKAPK5_ST	P25685	DNAJB1	Q8IW41	MAPKAPK5	S151	R148H	148	Missense	distal	-3	no	43.868	36.840	EPSD;PhosphoSitePlus	COSMIC	23.028	Down-regulation
CAMK_MAPKAPK_MK5_MAPKAPK5_ST	P25685	DNAJB1	Q8IW41	MAPKAPK5	S151	A152T	152	Missense	proximal	1	no	43.868	43.807	EPSD;PhosphoSitePlus	COSMIC	23.028	Down-regulation
CAMK_MAPKAPK_MK5_MAPKAPK5_ST	P25685	DNAJB1	Q8IW41	MAPKAPK5	S151	A156V	156	Missense	distal	5	no	43.868	38.712	EPSD;PhosphoSitePlus	COSMIC	23.028	Down-regulation
CAMK_MAPKAPK_MK5_MAPKAPK5_ST	P25685	DNAJB1	Q8IW41	MAPKAPK5	S151	R157Q	157	Missense	distal	6	no	43.868	43.809	EPSD;PhosphoSitePlus	COSMIC	23.028	Down-regulation
CAMK_MAPKAPK_MK5_MAPKAPK5_ST	P25685	DNAJB1	Q8IW41	MAPKAPK5	S171	S171F	171	Missense	central	0	yes	41.324	0.000	PhosphoSitePlus;EPSD	COSMIC	23.028	Loss
CAMK_MAPKAPK_MK5_MAPKAPK5_ST	P25685	DNAJB1	Q8IW41	MAPKAPK5	S186	M183I	183	Missense	distal	-3	no	20.074	30.217	EPSD	COSMIC	23.028	Gain
CAMK_MAPKAPK_MK5_MAPKAPK5_ST	P25685	DNAJB1	Q8IW41	MAPKAPK5	S196	R198G	198	Missense	proximal	2	no	25.589	28.517	EPSD	COSMIC	23.028	Up-regulation
CAMK_MAPKAPK_MK5_MAPKAPK5_ST	P25685	DNAJB1	Q8IW41	MAPKAPK5	S196	E200D	200	Missense	distal	4	no	25.589	25.736	EPSD	COSMIC	23.028	Up-regulation
CAMK_MAPKAPK_MK5_MAPKAPK5_ST	P25685	DNAJB1	Q8IW41	MAPKAPK5	S196	N199S	199	Missense	distal	3	no	25.589	25.784	EPSD	COSMIC;GDSC;CCLE	23.028	Up-regulation
CAMK_MAPKAPK_MK5_MAPKAPK5_ST	P25685	DNAJB1	Q8IW41	MAPKAPK5	S196	E200K	200	Missense	distal	4	no	25.589	25.628	EPSD	COSMIC	23.028	Up-regulation
CAMK_MAPKAPK_MK5_MAPKAPK5_ST	P25685	DNAJB1	Q8IW41	MAPKAPK5	S228	T227I	227	Missense	proximal	-1	no	16.585	23.849	EPSD	COSMIC;CCLE	23.028	Gain
CAMK_MAPKAPK_MK5_MAPKAPK5_ST	P04637	TP53	Q8IW41	MAPKAPK5	S6	P8S	8	Missense	proximal	2	no	17.633	23.780	EPSD	COSMIC	23.028	Gain
CAMK_MAPKAPK_MK5_MAPKAPK5_ST	P04637	TP53	Q8IW41	MAPKAPK5	S15	E11Q	11	Missense	distal	-4	no	28.717	28.559	EPSD	COSMIC;GDSC;CCLE	23.028	Down-regulation
CAMK_MAPKAPK_MK5_MAPKAPK5_ST	P04637	TP53	Q8IW41	MAPKAPK5	S15	S20L	20	Missense	distal	5	no	28.717	22.543	EPSD	COSMIC	23.028	Loss
CAMK_MAPKAPK_MK5_MAPKAPK5_ST	P04637	TP53	Q8IW41	MAPKAPK5	S15	Q16L	16	Missense	proximal	1	no	28.717	28.710	EPSD	COSMIC;GDSC;CCLE	23.028	Down-regulation
CAMK_MAPKAPK_MK5_MAPKAPK5_ST	P04637	TP53	Q8IW41	MAPKAPK5	S15	P13S	13	Missense	proximal	-2	no	28.717	28.528	EPSD	COSMIC	23.028	Down-regulation
CAMK_MAPKAPK_MK5_MAPKAPK5_ST	P04637	TP53	Q8IW41	MAPKAPK5	S15	E17K	17	Missense	proximal	2	no	28.717	27.432	EPSD	COSMIC	23.028	Down-regulation
CAMK_MAPKAPK_MK5_MAPKAPK5_ST	P04637	TP53	Q8IW41	MAPKAPK5	S15	V10I	10	Missense	distal	-5	no	28.717	29.284	EPSD	COSMIC	23.028	Up-regulation
CAMK_MAPKAPK_MK5_MAPKAPK5_ST	P04637	TP53	Q8IW41	MAPKAPK5	S15	P8L	8	Missense	distal	-7	no	28.717	28.974	EPSD	COSMIC	23.028	Up-regulation
CAMK_MAPKAPK_MK5_MAPKAPK5_ST	P04637	TP53	Q8IW41	MAPKAPK5	S15	P8S	8	Missense	distal	-7	no	28.717	29.372	EPSD	COSMIC	23.028	Up-regulation
CAMK_MAPKAPK_MK5_MAPKAPK5_ST	P04637	TP53	Q8IW41	MAPKAPK5	S15	V10G	10	Missense	distal	-5	no	28.717	22.857	EPSD	COSMIC	23.028	Loss
CAMK_MAPKAPK_MK5_MAPKAPK5_ST	P04637	TP53	Q8IW41	MAPKAPK5	S15	T18A	18	Missense	distal	3	no	28.717	28.770	EPSD	COSMIC	23.028	Up-regulation
CAMK_MAPKAPK_MK5_MAPKAPK5_ST	P04637	TP53	Q8IW41	MAPKAPK5	S15	F19S	19	Missense	distal	4	no	28.717	28.581	EPSD	COSMIC	23.028	Down-regulation
CAMK_MAPKAPK_MK5_MAPKAPK5_ST	P04637	TP53	Q8IW41	MAPKAPK5	S15	E17V	17	Missense	proximal	2	no	28.717	24.952	EPSD	COSMIC	23.028	Down-regulation
CAMK_MAPKAPK_MK5_MAPKAPK5_ST	P04637	TP53	Q8IW41	MAPKAPK5	S15	S9G	9	Missense	distal	-6	no	28.717	28.726	EPSD	COSMIC	23.028	Up-regulation
CAMK_MAPKAPK_MK5_MAPKAPK5_ST	P04637	TP53	Q8IW41	MAPKAPK5	S15	T18I	18	Missense	distal	3	no	28.717	29.115	EPSD	COSMIC	23.028	Up-regulation
CAMK_MAPKAPK_MK5_MAPKAPK5_ST	P04637	TP53	Q8IW41	MAPKAPK5	S15	T18K	18	Missense	distal	3	no	28.717	28.899	EPSD	COSMIC	23.028	Up-regulation
CAMK_MAPKAPK_MK5_MAPKAPK5_ST	P04637	TP53	Q8IW41	MAPKAPK5	S15	T18R	18	Missense	distal	3	no	28.717	28.551	EPSD	COSMIC	23.028	Down-regulation
CAMK_MAPKAPK_MK5_MAPKAPK5_ST	P04637	TP53	Q8IW41	MAPKAPK5	S15	S15I	15	Missense	central	0	yes	28.717	0.000	EPSD	COSMIC	23.028	Loss
CAMK_MAPKAPK_MK5_MAPKAPK5_ST	P04637	TP53	Q8IW41	MAPKAPK5	S37	M40I	40	Missense	distal	3	no	42.124	42.356	PhosphoSitePlus	COSMIC	23.028	Up-regulation
CAMK_MAPKAPK_MK5_MAPKAPK5_ST	P04637	TP53	Q8IW41	MAPKAPK5	S37	V31I	31	Missense	distal	-6	no	42.124	41.883	PhosphoSitePlus	COSMIC;GDSC;CCLE	23.028	Down-regulation
CAMK_MAPKAPK_MK5_MAPKAPK5_ST	P04637	TP53	Q8IW41	MAPKAPK5	S37	P36L	36	Missense	proximal	-1	no	42.124	44.365	PhosphoSitePlus	COSMIC;GDSC;CCLE	23.028	Up-regulation
CAMK_MAPKAPK_MK5_MAPKAPK5_ST	P04637	TP53	Q8IW41	MAPKAPK5	S37	S33T	33	Missense	distal	-4	no	42.124	41.862	PhosphoSitePlus	COSMIC	23.028	Down-regulation
CAMK_MAPKAPK_MK5_MAPKAPK5_ST	P04637	TP53	Q8IW41	MAPKAPK5	S37	D41N	41	Missense	distal	4	no	42.124	42.021	PhosphoSitePlus	COSMIC	23.028	Down-regulation
CAMK_MAPKAPK_MK5_MAPKAPK5_ST	P04637	TP53	Q8IW41	MAPKAPK5	S37	L35F	35	Missense	proximal	-2	no	42.124	42.352	PhosphoSitePlus	COSMIC	23.028	Up-regulation
CAMK_MAPKAPK_MK5_MAPKAPK5_ST	P04637	TP53	Q8IW41	MAPKAPK5	S37	Q38L	38	Missense	proximal	1	no	42.124	42.117	PhosphoSitePlus	COSMIC	23.028	Down-regulation
CAMK_MAPKAPK_MK5_MAPKAPK5_ST	P04637	TP53	Q8IW41	MAPKAPK5	S37	M44I	44	Missense	distal	7	no	42.124	41.727	PhosphoSitePlus	COSMIC	23.028	Down-regulation
CAMK_MAPKAPK_MK5_MAPKAPK5_ST	P04637	TP53	Q8IW41	MAPKAPK5	S37	P36S	36	Missense	proximal	-1	no	42.124	34.840	PhosphoSitePlus	COSMIC;GDSC;CCLE	23.028	Down-regulation
CAMK_MAPKAPK_MK5_MAPKAPK5_ST	P04637	TP53	Q8IW41	MAPKAPK5	S37	A39V	39	Missense	proximal	2	no	42.124	39.252	PhosphoSitePlus	COSMIC	23.028	Down-regulation
CAMK_MAPKAPK_MK5_MAPKAPK5_ST	P04637	TP53	Q8IW41	MAPKAPK5	S37	A39S	39	Missense	proximal	2	no	42.124	44.026	PhosphoSitePlus	COSMIC	23.028	Up-regulation
CAMK_MAPKAPK_MK5_MAPKAPK5_ST	P04637	TP53	Q8IW41	MAPKAPK5	S37	D42Y	42	Missense	distal	5	no	42.124	38.377	PhosphoSitePlus	COSMIC	23.028	Down-regulation
CAMK_MAPKAPK_MK5_MAPKAPK5_ST	P04637	TP53	Q8IW41	MAPKAPK5	S37	M44R	44	Missense	distal	7	no	42.124	42.298	PhosphoSitePlus	COSMIC	23.028	Up-regulation
CAMK_MAPKAPK_MK5_MAPKAPK5_ST	P04637	TP53	Q8IW41	MAPKAPK5	S37	M44V	44	Missense	distal	7	no	42.124	42.309	PhosphoSitePlus	COSMIC	23.028	Up-regulation
CAMK_MAPKAPK_MK5_MAPKAPK5_ST	P04637	TP53	Q8IW41	MAPKAPK5	S37	N30K	30	Missense	distal	-7	no	42.124	41.704	PhosphoSitePlus	COSMIC	23.028	Down-regulation
CAMK_MAPKAPK_MK5_MAPKAPK5_ST	P04637	TP53	Q8IW41	MAPKAPK5	S37	M44T	44	Missense	distal	7	no	42.124	41.987	PhosphoSitePlus	COSMIC	23.028	Down-regulation
CAMK_MAPKAPK_MK5_MAPKAPK5_ST	P04637	TP53	Q8IW41	MAPKAPK5	S37	A39T	39	Missense	proximal	2	no	42.124	41.412	PhosphoSitePlus	COSMIC	23.028	Down-regulation
CAMK_MAPKAPK_MK5_MAPKAPK5_ST	P04637	TP53	Q8IW41	MAPKAPK5	S37	L43F	43	Missense	distal	6	no	42.124	42.084	PhosphoSitePlus	COSMIC	23.028	Down-regulation
CAMK_MAPKAPK_MK5_MAPKAPK5_ST	P04637	TP53	Q8IW41	MAPKAPK5	S37	D41H	41	Missense	distal	4	no	42.124	41.995	PhosphoSitePlus	COSMIC	23.028	Down-regulation
CAMK_MAPKAPK_MK5_MAPKAPK5_ST	P04637	TP53	Q8IW41	MAPKAPK5	S37	P36R	36	Missense	proximal	-1	no	42.124	38.510	PhosphoSitePlus	COSMIC	23.028	Down-regulation
CAMK_MAPKAPK_MK5_MAPKAPK5_ST	P04637	TP53	Q8IW41	MAPKAPK5	S37	L35R	35	Missense	proximal	-2	no	42.124	42.116	PhosphoSitePlus	COSMIC	23.028	Down-regulation
CAMK_MAPKAPK_MK5_MAPKAPK5_ST	P04637	TP53	Q8IW41	MAPKAPK5	S37	L35H	35	Missense	proximal	-2	no	42.124	41.664	PhosphoSitePlus	COSMIC	23.028	Down-regulation
CAMK_MAPKAPK_MK5_MAPKAPK5_ST	P04637	TP53	Q8IW41	MAPKAPK5	S37	L35I	35	Missense	proximal	-2	no	42.124	41.680	PhosphoSitePlus	COSMIC	23.028	Down-regulation
CAMK_MAPKAPK_MK5_MAPKAPK5_ST	P04637	TP53	Q8IW41	MAPKAPK5	S37	L35V	35	Missense	proximal	-2	no	42.124	42.057	PhosphoSitePlus	COSMIC	23.028	Down-regulation
CAMK_MAPKAPK_MK5_MAPKAPK5_ST	P04637	TP53	Q8IW41	MAPKAPK5	S37	D41E	41	Missense	distal	4	no	42.124	41.977	PhosphoSitePlus	COSMIC	23.028	Down-regulation
CAMK_MAPKAPK_MK5_MAPKAPK5_ST	P04637	TP53	Q8IW41	MAPKAPK5	S46	M40I	40	Missense	distal	-6	no	26.832	26.817	EPSD	COSMIC	23.028	Down-regulation
CAMK_MAPKAPK_MK5_MAPKAPK5_ST	P04637	TP53	Q8IW41	MAPKAPK5	S46	W53C	53	Missense	distal	7	no	26.832	26.503	EPSD	COSMIC	23.028	Down-regulation
CAMK_MAPKAPK_MK5_MAPKAPK5_ST	P04637	TP53	Q8IW41	MAPKAPK5	S46	W53G	53	Missense	distal	7	no	26.832	26.781	EPSD	COSMIC	23.028	Down-regulation
CAMK_MAPKAPK_MK5_MAPKAPK5_ST	P04637	TP53	Q8IW41	MAPKAPK5	S46	S46F	46	Missense	central	0	yes	26.832	0.000	EPSD	COSMIC	23.028	Loss
CAMK_MAPKAPK_MK5_MAPKAPK5_ST	P04637	TP53	Q8IW41	MAPKAPK5	S46	D49Y	49	Missense	distal	3	no	26.832	26.813	EPSD	COSMIC	23.028	Down-regulation
CAMK_MAPKAPK_MK5_MAPKAPK5_ST	P04637	TP53	Q8IW41	MAPKAPK5	S46	P47L	47	Missense	proximal	1	no	26.832	26.798	EPSD	COSMIC	23.028	Down-regulation
CAMK_MAPKAPK_MK5_MAPKAPK5_ST	P04637	TP53	Q8IW41	MAPKAPK5	S46	D49H	49	Missense	distal	3	no	26.832	26.934	EPSD	COSMIC;GDSC;CCLE	23.028	Up-regulation
CAMK_MAPKAPK_MK5_MAPKAPK5_ST	P04637	TP53	Q8IW41	MAPKAPK5	S46	P47S	47	Missense	proximal	1	no	26.832	26.775	EPSD	COSMIC	23.028	Down-regulation
CAMK_MAPKAPK_MK5_MAPKAPK5_ST	P04637	TP53	Q8IW41	MAPKAPK5	S46	D41N	41	Missense	distal	-5	no	26.832	31.496	EPSD	COSMIC	23.028	Up-regulation
CAMK_MAPKAPK_MK5_MAPKAPK5_ST	P04637	TP53	Q8IW41	MAPKAPK5	S46	D48H	48	Missense	proximal	2	no	26.832	27.835	EPSD	COSMIC	23.028	Up-regulation
CAMK_MAPKAPK_MK5_MAPKAPK5_ST	P04637	TP53	Q8IW41	MAPKAPK5	S46	D49N	49	Missense	distal	3	no	26.832	26.855	EPSD	COSMIC	23.028	Up-regulation
CAMK_MAPKAPK_MK5_MAPKAPK5_ST	P04637	TP53	Q8IW41	MAPKAPK5	S46	M44I	44	Missense	proximal	-2	no	26.832	26.486	EPSD	COSMIC	23.028	Down-regulation
CAMK_MAPKAPK_MK5_MAPKAPK5_ST	P04637	TP53	Q8IW41	MAPKAPK5	S46	Q52H	52	Missense	distal	6	no	26.832	26.751	EPSD	COSMIC	23.028	Down-regulation
CAMK_MAPKAPK_MK5_MAPKAPK5_ST	P04637	TP53	Q8IW41	MAPKAPK5	S46	D49V	49	Missense	distal	3	no	26.832	26.722	EPSD	COSMIC	23.028	Down-regulation
CAMK_MAPKAPK_MK5_MAPKAPK5_ST	P04637	TP53	Q8IW41	MAPKAPK5	S46	A39V	39	Missense	distal	-7	no	26.832	26.410	EPSD	COSMIC	23.028	Down-regulation
CAMK_MAPKAPK_MK5_MAPKAPK5_ST	P04637	TP53	Q8IW41	MAPKAPK5	S46	A39S	39	Missense	distal	-7	no	26.832	26.795	EPSD	COSMIC	23.028	Down-regulation
CAMK_MAPKAPK_MK5_MAPKAPK5_ST	P04637	TP53	Q8IW41	MAPKAPK5	S46	D42Y	42	Missense	distal	-4	no	26.832	26.658	EPSD	COSMIC	23.028	Down-regulation
CAMK_MAPKAPK_MK5_MAPKAPK5_ST	P04637	TP53	Q8IW41	MAPKAPK5	S46	M44R	44	Missense	proximal	-2	no	26.832	26.922	EPSD	COSMIC	23.028	Up-regulation
CAMK_MAPKAPK_MK5_MAPKAPK5_ST	P04637	TP53	Q8IW41	MAPKAPK5	S46	S46P	46	Missense	central	0	yes	26.832	0.000	EPSD	COSMIC	23.028	Loss
CAMK_MAPKAPK_MK5_MAPKAPK5_ST	P04637	TP53	Q8IW41	MAPKAPK5	S46	M44V	44	Missense	proximal	-2	no	26.832	26.863	EPSD	COSMIC	23.028	Up-regulation
CAMK_MAPKAPK_MK5_MAPKAPK5_ST	P04637	TP53	Q8IW41	MAPKAPK5	S46	L45P	45	Missense	proximal	-1	no	26.832	24.591	EPSD	COSMIC	23.028	Down-regulation
CAMK_MAPKAPK_MK5_MAPKAPK5_ST	P04637	TP53	Q8IW41	MAPKAPK5	S46	M44T	44	Missense	proximal	-2	no	26.832	26.782	EPSD	COSMIC	23.028	Down-regulation
CAMK_MAPKAPK_MK5_MAPKAPK5_ST	P04637	TP53	Q8IW41	MAPKAPK5	S46	A39T	39	Missense	distal	-7	no	26.832	26.521	EPSD	COSMIC	23.028	Down-regulation
CAMK_MAPKAPK_MK5_MAPKAPK5_ST	P04637	TP53	Q8IW41	MAPKAPK5	S46	L43F	43	Missense	distal	-3	no	26.832	32.763	EPSD	COSMIC	23.028	Up-regulation
CAMK_MAPKAPK_MK5_MAPKAPK5_ST	P04637	TP53	Q8IW41	MAPKAPK5	S46	D41H	41	Missense	distal	-5	no	26.832	32.770	EPSD	COSMIC	23.028	Up-regulation
CAMK_MAPKAPK_MK5_MAPKAPK5_ST	P04637	TP53	Q8IW41	MAPKAPK5	S46	D49E	49	Missense	distal	3	no	26.832	26.821	EPSD	COSMIC	23.028	Down-regulation
CAMK_MAPKAPK_MK5_MAPKAPK5_ST	P04637	TP53	Q8IW41	MAPKAPK5	S46	D49G	49	Missense	distal	3	no	26.832	26.643	EPSD	COSMIC	23.028	Down-regulation
CAMK_MAPKAPK_MK5_MAPKAPK5_ST	P04637	TP53	Q8IW41	MAPKAPK5	S46	D48A	48	Missense	proximal	2	no	26.832	28.107	EPSD	COSMIC	23.028	Up-regulation
CAMK_MAPKAPK_MK5_MAPKAPK5_ST	P04637	TP53	Q8IW41	MAPKAPK5	S46	D48Y	48	Missense	proximal	2	no	26.832	26.852	EPSD	COSMIC	23.028	Up-regulation
CAMK_MAPKAPK_MK5_MAPKAPK5_ST	P04637	TP53	Q8IW41	MAPKAPK5	S46	D48E	48	Missense	proximal	2	no	26.832	28.999	EPSD	COSMIC	23.028	Up-regulation
CAMK_MAPKAPK_MK5_MAPKAPK5_ST	P04637	TP53	Q8IW41	MAPKAPK5	S46	D49I	49	Missense	distal	3	no	26.832	27.120	EPSD	COSMIC	23.028	Up-regulation
CAMK_MAPKAPK_MK5_MAPKAPK5_ST	P04637	TP53	Q8IW41	MAPKAPK5	S46	D41E	41	Missense	distal	-5	no	26.832	31.024	EPSD	COSMIC	23.028	Up-regulation
CAMK_MAPKAPK_MK5_MAPKAPK5_ST	P04637	TP53	Q8IW41	MAPKAPK5	S127	C124F	124	Missense	distal	-3	no	22.875	25.563	EPSD	COSMIC	23.028	Gain
CAMK_MAPKAPK_MK5_MAPKAPK5_ST	P04637	TP53	Q8IW41	MAPKAPK5	S127	C124T	124	Missense	distal	-3	no	22.875	23.278	EPSD	COSMIC	23.028	Gain
CAMK_MAPKAPK_MK5_MAPKAPK5_ST	P04637	TP53	Q8IW41	MAPKAPK5	S127	K120T	120	Missense	distal	-7	no	22.875	23.110	EPSD	COSMIC	23.028	Gain
CAMK_MAPKAPK_MK5_MAPKAPK5_ST	P04637	TP53	Q8IW41	MAPKAPK5	S127	T123I	123	Missense	distal	-4	no	22.875	23.432	EPSD	COSMIC	23.028	Gain
CAMK_MAPKAPK_MK5_MAPKAPK5_ST	P04637	TP53	Q8IW41	MAPKAPK5	S127	L130I	130	Missense	distal	3	no	22.875	23.212	EPSD	COSMIC	23.028	Gain
CAMK_MAPKAPK_MK5_MAPKAPK5_ST	P04637	TP53	Q8IW41	MAPKAPK5	S127	S121F	121	Missense	distal	-6	no	22.875	23.100	EPSD	COSMIC	23.028	Gain
CAMK_MAPKAPK_MK5_MAPKAPK5_ST	P04637	TP53	Q8IW41	MAPKAPK5	S127	K120Q	120	Missense	distal	-7	no	22.875	23.241	EPSD	COSMIC	23.028	Gain
CAMK_MAPKAPK_MK5_MAPKAPK5_ST	P04637	TP53	Q8IW41	MAPKAPK5	S183	L188Q	188	Missense	distal	5	no	20.709	25.527	EPSD	COSMIC	23.028	Gain
CAMK_MAPKAPK_MK5_MAPKAPK5_ST	P04637	TP53	Q8IW41	MAPKAPK5	S183	L188M	188	Missense	distal	5	no	20.709	25.522	EPSD	COSMIC	23.028	Gain
CAMK_MAPKAPK_MK5_MAPKAPK5_ST	P04637	TP53	Q8IW41	MAPKAPK5	S314	S313C	313	Missense	proximal	-1	no	17.097	27.116	EPSD	COSMIC	23.028	Gain
CAMK_MAPKAPK_MK5_MAPKAPK5_ST	P04637	TP53	Q8IW41	MAPKAPK5	S314	P316S	316	Missense	proximal	2	no	17.097	23.244	EPSD	COSMIC	23.028	Gain
CAMK_MAPKAPK_MK5_MAPKAPK5_ST	P04637	TP53	Q8IW41	MAPKAPK5	S315	S314C	314	Missense	proximal	-1	no	15.870	25.889	EPSD	COSMIC	23.028	Gain
CAMK_MAPKAPK_MK5_MAPKAPK5_ST	P04637	TP53	Q8IW41	MAPKAPK5	S362	S367F	367	Missense	distal	5	no	29.531	27.794	EPSD	COSMIC	23.028	Down-regulation
CAMK_MAPKAPK_MK5_MAPKAPK5_ST	P04637	TP53	Q8IW41	MAPKAPK5	S362	G361E	361	Missense	proximal	-1	no	29.531	31.281	EPSD	COSMIC	23.028	Up-regulation
CAMK_MAPKAPK_MK5_MAPKAPK5_ST	P04637	TP53	Q8IW41	MAPKAPK5	S362	E358V	358	Missense	distal	-4	no	29.531	29.233	EPSD	COSMIC	23.028	Down-regulation
CAMK_MAPKAPK_MK5_MAPKAPK5_ST	P04637	TP53	Q8IW41	MAPKAPK5	S362	P359S	359	Missense	distal	-3	no	29.531	27.663	EPSD	COSMIC	23.028	Down-regulation
CAMK_MAPKAPK_MK5_MAPKAPK5_ST	P04637	TP53	Q8IW41	MAPKAPK5	S362	A364D	364	Missense	proximal	2	no	29.531	28.256	EPSD	COSMIC	23.028	Down-regulation
CAMK_MAPKAPK_MK5_MAPKAPK5_ST	P04637	TP53	Q8IW41	MAPKAPK5	S362	H365Y	365	Missense	distal	3	no	29.531	29.410	EPSD	COSMIC	23.028	Down-regulation
CAMK_MAPKAPK_MK5_MAPKAPK5_ST	P04637	TP53	Q8IW41	MAPKAPK5	S362	G360A	360	Missense	proximal	-2	no	29.531	29.701	EPSD	COSMIC	23.028	Up-regulation
CAMK_MAPKAPK_MK5_MAPKAPK5_ST	P04637	TP53	Q8IW41	MAPKAPK5	S362	A364T	364	Missense	proximal	2	no	29.531	28.819	EPSD	COSMIC	23.028	Down-regulation
CAMK_MAPKAPK_MK5_MAPKAPK5_ST	P04637	TP53	Q8IW41	MAPKAPK5	S362	G356W	356	Missense	distal	-6	no	29.531	29.760	EPSD	COSMIC	23.028	Up-regulation
CAMK_MAPKAPK_MK5_MAPKAPK5_ST	P04637	TP53	Q8IW41	MAPKAPK5	S362	S366A	366	Missense	distal	4	no	29.531	29.562	EPSD	COSMIC	23.028	Up-regulation
CAMK_MAPKAPK_MK5_MAPKAPK5_ST	P04637	TP53	Q8IW41	MAPKAPK5	S362	E358Q	358	Missense	distal	-4	no	29.531	29.373	EPSD	COSMIC	23.028	Down-regulation
CAMK_MAPKAPK_MK5_MAPKAPK5_ST	P04637	TP53	Q8IW41	MAPKAPK5	S362	G361R	361	Missense	proximal	-1	no	29.531	34.799	EPSD	COSMIC	23.028	Up-regulation
CAMK_MAPKAPK_MK5_MAPKAPK5_ST	P04637	TP53	Q8IW41	MAPKAPK5	S362	E358K	358	Missense	distal	-4	no	29.531	29.406	EPSD	COSMIC	23.028	Down-regulation
CAMK_MAPKAPK_MK5_MAPKAPK5_ST	P04637	TP53	Q8IW41	MAPKAPK5	S366	S367F	367	Missense	proximal	1	no	31.733	31.751	EPSD	COSMIC	23.028	Up-regulation
CAMK_MAPKAPK_MK5_MAPKAPK5_ST	P04637	TP53	Q8IW41	MAPKAPK5	S366	K370N	370	Missense	distal	4	no	31.733	31.738	EPSD	COSMIC	23.028	Up-regulation
CAMK_MAPKAPK_MK5_MAPKAPK5_ST	P04637	TP53	Q8IW41	MAPKAPK5	S366	G361E	361	Missense	distal	-5	no	31.733	34.209	EPSD	COSMIC	23.028	Up-regulation
CAMK_MAPKAPK_MK5_MAPKAPK5_ST	P04637	TP53	Q8IW41	MAPKAPK5	S366	P359S	359	Missense	distal	-7	no	31.733	32.388	EPSD	COSMIC	23.028	Up-regulation
CAMK_MAPKAPK_MK5_MAPKAPK5_ST	P04637	TP53	Q8IW41	MAPKAPK5	S366	A364D	364	Missense	proximal	-2	no	31.733	31.674	EPSD	COSMIC	23.028	Down-regulation
CAMK_MAPKAPK_MK5_MAPKAPK5_ST	P04637	TP53	Q8IW41	MAPKAPK5	S366	H365Y	365	Missense	proximal	-1	no	31.733	28.088	EPSD	COSMIC	23.028	Down-regulation
CAMK_MAPKAPK_MK5_MAPKAPK5_ST	P04637	TP53	Q8IW41	MAPKAPK5	S366	G360A	360	Missense	distal	-6	no	31.733	31.900	EPSD	COSMIC	23.028	Up-regulation
CAMK_MAPKAPK_MK5_MAPKAPK5_ST	P04637	TP53	Q8IW41	MAPKAPK5	S366	A364T	364	Missense	proximal	-2	no	31.733	31.497	EPSD	COSMIC	23.028	Down-regulation
CAMK_MAPKAPK_MK5_MAPKAPK5_ST	P04637	TP53	Q8IW41	MAPKAPK5	S366	S366A	366	Missense	central	0	yes	31.733	0.000	EPSD	COSMIC	23.028	Loss
CAMK_MAPKAPK_MK5_MAPKAPK5_ST	P04637	TP53	Q8IW41	MAPKAPK5	S366	G361R	361	Missense	distal	-5	no	31.733	33.424	EPSD	COSMIC	23.028	Up-regulation
CAMK_MAPKAPK_MK5_MAPKAPK5_ST	P04637	TP53	Q8IW41	MAPKAPK5	S366	K370Q	370	Missense	distal	4	no	31.733	31.732	EPSD	COSMIC	23.028	Down-regulation
CAMK_MAPKAPK_MK5_MAPKAPK5_ST	P04637	TP53	Q8IW41	MAPKAPK5	S366	K373R	373	Missense	distal	7	no	31.733	31.984	EPSD	COSMIC	23.028	Up-regulation
CAMK_MAPKAPK_MK5_MAPKAPK5_ST	P04637	TP53	Q8IW41	MAPKAPK5	S366	S371P	371	Missense	distal	5	no	31.733	27.967	EPSD	COSMIC	23.028	Down-regulation
CAMK_MAPKAPK_MK5_MAPKAPK5_ST	P04637	TP53	Q8IW41	MAPKAPK5	S371	S367F	367	Missense	distal	-4	no	24.928	24.449	EPSD	COSMIC	23.028	Down-regulation
CAMK_MAPKAPK_MK5_MAPKAPK5_ST	P04637	TP53	Q8IW41	MAPKAPK5	S371	K370N	370	Missense	proximal	-1	no	24.928	23.110	EPSD	COSMIC	23.028	Down-regulation
CAMK_MAPKAPK_MK5_MAPKAPK5_ST	P04637	TP53	Q8IW41	MAPKAPK5	S371	A364D	364	Missense	distal	-7	no	24.928	24.353	EPSD	COSMIC	23.028	Down-regulation
CAMK_MAPKAPK_MK5_MAPKAPK5_ST	P04637	TP53	Q8IW41	MAPKAPK5	S371	H365Y	365	Missense	distal	-6	no	24.928	25.144	EPSD	COSMIC	23.028	Up-regulation
CAMK_MAPKAPK_MK5_MAPKAPK5_ST	P04637	TP53	Q8IW41	MAPKAPK5	S371	A364T	364	Missense	distal	-7	no	24.928	24.618	EPSD	COSMIC	23.028	Down-regulation
CAMK_MAPKAPK_MK5_MAPKAPK5_ST	P04637	TP53	Q8IW41	MAPKAPK5	S371	S376T	376	Missense	distal	5	no	24.928	24.029	EPSD	COSMIC	23.028	Down-regulation
CAMK_MAPKAPK_MK5_MAPKAPK5_ST	P04637	TP53	Q8IW41	MAPKAPK5	S371	S366A	366	Missense	distal	-5	no	24.928	26.880	EPSD	COSMIC	23.028	Up-regulation
CAMK_MAPKAPK_MK5_MAPKAPK5_ST	P04637	TP53	Q8IW41	MAPKAPK5	S371	T377I	377	Missense	distal	6	no	24.928	24.780	EPSD	COSMIC	23.028	Down-regulation
CAMK_MAPKAPK_MK5_MAPKAPK5_ST	P04637	TP53	Q8IW41	MAPKAPK5	S371	S378F	378	Missense	distal	7	no	24.928	24.986	EPSD	COSMIC	23.028	Up-regulation
CAMK_MAPKAPK_MK5_MAPKAPK5_ST	P04637	TP53	Q8IW41	MAPKAPK5	S371	K370Q	370	Missense	proximal	-1	no	24.928	22.667	EPSD	COSMIC	23.028	Loss
CAMK_MAPKAPK_MK5_MAPKAPK5_ST	P04637	TP53	Q8IW41	MAPKAPK5	S371	K373R	373	Missense	proximal	2	no	24.928	21.934	EPSD	COSMIC	23.028	Loss
CAMK_MAPKAPK_MK5_MAPKAPK5_ST	P04637	TP53	Q8IW41	MAPKAPK5	S371	S376F	376	Missense	distal	5	no	24.928	23.192	EPSD	COSMIC	23.028	Down-regulation
CAMK_MAPKAPK_MK5_MAPKAPK5_ST	P04637	TP53	Q8IW41	MAPKAPK5	S371	G374S	374	Missense	distal	3	no	24.928	25.335	EPSD	COSMIC	23.028	Up-regulation
CAMK_MAPKAPK_MK5_MAPKAPK5_ST	P04637	TP53	Q8IW41	MAPKAPK5	S371	S376A	376	Missense	distal	5	no	24.928	23.309	EPSD	COSMIC	23.028	Down-regulation
CAMK_MAPKAPK_MK5_MAPKAPK5_ST	P04637	TP53	Q8IW41	MAPKAPK5	S371	S371P	371	Missense	central	0	yes	24.928	0.000	EPSD	COSMIC	23.028	Loss
CAMK_MAPKAPK_MK5_MAPKAPK5_ST	P04637	TP53	Q8IW41	MAPKAPK5	S376	K373R	373	Missense	distal	-3	no	16.268	33.048	EPSD	COSMIC	23.028	Gain
CAMK_MAPKAPK_MK5_MAPKAPK5_ST	Q15382	RHEB	Q8IW41	MAPKAPK5	S130	R127S	127	Missense	distal	-3	no	43.637	30.650	PhosphoSitePlus	COSMIC	23.028	Down-regulation
CAMK_MAPKAPK_MK5_MAPKAPK5_ST	Q15382	RHEB	Q8IW41	MAPKAPK5	S130	E133K	133	Missense	distal	3	no	43.637	43.720	PhosphoSitePlus	COSMIC	23.028	Up-regulation
CAMK_MAPKAPK_MK5_MAPKAPK5_ST	P07101	TH	Q8IW41	MAPKAPK5	S19	R15S	15	Missense	distal	-4	no	38.309	38.456	PhosphoSitePlus;EPSD	COSMIC	23.028	Up-regulation
CAMK_MAPKAPK_MK5_MAPKAPK5_ST	P07101	TH	Q8IW41	MAPKAPK5	S19	A17V	17	Missense	proximal	-2	no	38.309	38.153	PhosphoSitePlus;EPSD	COSMIC;CCLE	23.028	Down-regulation
CAMK_MAPKAPK_MK5_MAPKAPK5_ST	P07101	TH	Q8IW41	MAPKAPK5	S19	S19C	19	Missense	central	0	yes	38.309	0.000	PhosphoSitePlus;EPSD	COSMIC;GDSC;CCLE	23.028	Loss
CAMK_MAPKAPK_MK5_MAPKAPK5_ST	P07101	TH	Q8IW41	MAPKAPK5	S19	V18M	18	Missense	proximal	-1	no	38.309	28.692	PhosphoSitePlus;EPSD	COSMIC	23.028	Down-regulation
CAMK_MAPKAPK_MK5_MAPKAPK5_ST	P07101	TH	Q8IW41	MAPKAPK5	S40	G38W	38	Missense	proximal	-2	no	28.104	28.376	EPSD;PhosphoSitePlus	COSMIC	23.028	Up-regulation
CAMK_MAPKAPK_MK5_MAPKAPK5_ST	P07101	TH	Q8IW41	MAPKAPK5	S40	P45S	45	Missense	distal	5	no	28.104	31.870	EPSD;PhosphoSitePlus	COSMIC	23.028	Up-regulation
CAMK_MAPKAPK_MK5_MAPKAPK5_ST	P07101	TH	Q8IW41	MAPKAPK5	S40	A36T	36	Missense	distal	-4	no	28.104	28.147	EPSD;PhosphoSitePlus	COSMIC	23.028	Up-regulation
CAMK_MAPKAPK_MK5_MAPKAPK5_ST	P07101	TH	Q8IW41	MAPKAPK5	S40	P37L	37	Missense	distal	-3	no	28.104	23.830	EPSD;PhosphoSitePlus	COSMIC	23.028	Down-regulation
CAMK_MAPKAPK_MK5_MAPKAPK5_ST	P07101	TH	Q8IW41	MAPKAPK5	S40	P45L	45	Missense	distal	5	no	28.104	25.696	EPSD;PhosphoSitePlus	COSMIC	23.028	Down-regulation
CAMK_MAPKAPK_MK5_MAPKAPK5_ST	P07101	TH	Q8IW41	MAPKAPK5	S40	P47H	47	Missense	distal	7	no	28.104	27.822	EPSD;PhosphoSitePlus	COSMIC	23.028	Down-regulation
CAMK_MAPKAPK_MK5_MAPKAPK5_ST	P07101	TH	Q8IW41	MAPKAPK5	S71	R64Q	64	Missense	distal	-7	no	38.327	38.887	EPSD	COSMIC;CCLE	23.028	Up-regulation
CAMK_MAPKAPK_MK5_MAPKAPK5_ST	P07101	TH	Q8IW41	MAPKAPK5	S435	L434M	434	Missense	proximal	-1	no	41.810	34.002	EPSD	COSMIC	23.028	Down-regulation
CAMK_MAPKAPK_MK5_MAPKAPK5_ST	P07101	TH	Q8IW41	MAPKAPK5	S435	E439A	439	Missense	distal	4	no	41.810	41.850	EPSD	COSMIC	23.028	Up-regulation
CAMK_MAPKAPK_MK5_MAPKAPK5_ST	P07101	TH	Q8IW41	MAPKAPK5	S435	G428W	428	Missense	distal	-7	no	41.810	41.217	EPSD	COSMIC	23.028	Down-regulation
CAMK_MAPKAPK_MK5_MAPKAPK5_ST	P07101	TH	Q8IW41	MAPKAPK5	S435	L430M	430	Missense	distal	-5	no	41.810	39.482	EPSD	COSMIC	23.028	Down-regulation
CAMK_DAPK_DAPK_DAPK2_ST	Q9UIK4	DAPK2	Q9UIK4	DAPK2	T275	R281K	281	Missense	distal	6	no	3.511	3.537	EPSD	COSMIC	1.958	Up-regulation
CAMK_DAPK_DAPK_DAPK2_ST	Q9UIK4	DAPK2	Q9UIK4	DAPK2	T275	I276V	276	Missense	proximal	1	no	3.511	3.509	EPSD	COSMIC	1.958	Down-regulation
CAMK_DAPK_DAPK_DAPK2_ST	Q9UIK4	DAPK2	Q9UIK4	DAPK2	S318	R312H	312	Missense	distal	-6	no	5.663	5.829	PhosphoSitePlus	COSMIC	1.958	Up-regulation
CAMK_DAPK_DAPK_DAPK2_ST	Q9UIK4	DAPK2	Q9UIK4	DAPK2	T369	S368R	368	Missense	proximal	-1	no	2.002	2.116	EPSD	COSMIC	1.958	Up-regulation
CAMK_DAPK_DAPK_DAPK2_ST	Q8N122	RPTOR	Q9UIK4	DAPK2	T700	S696Y	696	Missense	distal	-4	no	2.705	2.956	EPSD	COSMIC	1.958	Up-regulation
CAMK_DAPK_DAPK_DAPK2_ST	Q8N122	RPTOR	Q9UIK4	DAPK2	T700	A693T	693	Missense	distal	-7	no	2.705	2.692	EPSD	COSMIC;GDSC;CCLE	1.958	Down-regulation
CAMK_DAPK_DAPK_DAPK2_ST	Q8N122	RPTOR	Q9UIK4	DAPK2	T700	G702E	702	Missense	proximal	2	no	2.705	2.713	EPSD	COSMIC	1.958	Up-regulation
CAMK_DAPK_DAPK_DAPK2_ST	Q8N122	RPTOR	Q9UIK4	DAPK2	T700	S696A	696	Missense	distal	-4	no	2.705	2.771	EPSD	COSMIC	1.958	Up-regulation
CAMK_DAPK_DAPK_DAPK2_ST	Q8N122	RPTOR	Q9UIK4	DAPK2	S721	R718C	718	Missense	distal	-3	no	2.232	1.456	PhosphoSitePlus	COSMIC;CCLE	1.958	Loss
CAMK_DAPK_DAPK_DAPK2_ST	Q8N122	RPTOR	Q9UIK4	DAPK2	S721	P715S	715	Missense	distal	-6	no	2.232	2.414	PhosphoSitePlus	COSMIC	1.958	Up-regulation
CAMK_DAPK_DAPK_DAPK2_ST	Q8N122	RPTOR	Q9UIK4	DAPK2	S721	S719Y	719	Missense	proximal	-2	no	2.232	2.233	PhosphoSitePlus	COSMIC	1.958	Up-regulation
CAMK_DAPK_DAPK_DAPK2_ST	Q8N122	RPTOR	Q9UIK4	DAPK2	S721	S721N	721	Missense	central	0	yes	2.232	0.000	PhosphoSitePlus	COSMIC	1.958	Loss
CAMK_DAPK_DAPK_DAPK2_ST	Q8N122	RPTOR	Q9UIK4	DAPK2	S721	V720L	720	Missense	proximal	-1	no	2.232	2.228	PhosphoSitePlus	COSMIC	1.958	Down-regulation
CAMK_DAPK_DAPK_DAPK2_ST	Q8N122	RPTOR	Q9UIK4	DAPK2	T731	S738Y	738	Missense	distal	7	no	2.877	2.878	EPSD	COSMIC	1.958	Up-regulation
CAMK_DAPK_DAPK_DAPK2_ST	Q8N122	RPTOR	Q9UIK4	DAPK2	T731	A730T	730	Missense	proximal	-1	no	2.877	2.939	EPSD	COSMIC	1.958	Up-regulation
CAMK_DAPK_DAPK_DAPK2_ST	Q8N122	RPTOR	Q9UIK4	DAPK2	T731	T731A	731	Missense	central	0	yes	2.877	0.000	EPSD	COSMIC	1.958	Loss
CAMK_DAPK_DAPK_DAPK2_ST	Q8N122	RPTOR	Q9UIK4	DAPK2	S794	R789H	789	Missense	distal	-5	no	3.213	2.129	EPSD	COSMIC;GDSC;CCLE	1.958	Down-regulation
CAMK_DAPK_DAPK_DAPK2_ST	Q8N122	RPTOR	Q9UIK4	DAPK2	S794	R788C	788	Missense	distal	-6	no	3.213	3.422	EPSD	COSMIC;GDSC;CCLE	1.958	Up-regulation
CAMK_DAPK_DAPK_DAPK2_ST	Q8N122	RPTOR	Q9UIK4	DAPK2	S794	L796I	796	Missense	proximal	2	no	3.213	3.209	EPSD	COSMIC	1.958	Down-regulation
CAMK_DAPK_DAPK_DAPK2_ST	Q8N122	RPTOR	Q9UIK4	DAPK2	S794	R788H	788	Missense	distal	-6	no	3.213	3.379	EPSD	COSMIC	1.958	Up-regulation
CAMK_DAPK_DAPK_DAPK2_ST	Q8N122	RPTOR	Q9UIK4	DAPK2	S794	S798F	798	Missense	distal	4	no	3.213	3.217	EPSD	COSMIC	1.958	Up-regulation
CAMK_DAPK_DAPK_DAPK2_ST	Q8N122	RPTOR	Q9UIK4	DAPK2	S794	S792F	792	Missense	proximal	-2	no	3.213	3.206	EPSD	COSMIC	1.958	Down-regulation
CAMK_DAPK_DAPK_DAPK2_ST	Q8N122	RPTOR	Q9UIK4	DAPK2	S794	A790S	790	Missense	distal	-4	no	3.213	3.148	EPSD	COSMIC	1.958	Down-regulation
CAMK_DAPK_DAPK_DAPK2_ST	Q8N122	RPTOR	Q9UIK4	DAPK2	S794	L799H	799	Missense	distal	5	no	3.213	3.303	EPSD	COSMIC	1.958	Up-regulation
CAMK_DAPK_DAPK_DAPK2_ST	Q8N122	RPTOR	Q9UIK4	DAPK2	S854	P861L	861	Missense	distal	7	no	2.343	2.344	EPSD	COSMIC	1.958	Up-regulation
CAMK_DAPK_DAPK_DAPK2_ST	Q8N122	RPTOR	Q9UIK4	DAPK2	S854	V850I	850	Missense	distal	-4	no	2.343	2.210	EPSD	COSMIC	1.958	Down-regulation
CAMK_DAPK_DAPK_DAPK2_ST	Q8N122	RPTOR	Q9UIK4	DAPK2	S854	S854A	854	Missense	central	0	yes	2.343	0.000	EPSD	COSMIC	1.958	Loss
CAMK_DAPK_DAPK_DAPK2_ST	Q8N122	RPTOR	Q9UIK4	DAPK2	T857	P861L	861	Missense	distal	4	no	2.033	2.038	EPSD	COSMIC	1.958	Up-regulation
CAMK_DAPK_DAPK_DAPK2_ST	Q8N122	RPTOR	Q9UIK4	DAPK2	T857	V850I	850	Missense	distal	-7	no	2.033	2.076	EPSD	COSMIC	1.958	Up-regulation
CAMK_DAPK_DAPK_DAPK2_ST	Q8N122	RPTOR	Q9UIK4	DAPK2	T857	A862T	862	Missense	distal	5	no	2.033	2.023	EPSD	COSMIC	1.958	Down-regulation
CAMK_DAPK_DAPK_DAPK2_ST	Q8N122	RPTOR	Q9UIK4	DAPK2	T857	S854A	854	Missense	distal	-3	no	2.033	2.040	EPSD	COSMIC	1.958	Up-regulation
AGC_PKC_PKCh_PRKCH_ST	P05107	ITGB2	P24723	PRKCH	T118	A112T	112	Missense	distal	-6	no	24.636	24.813	EPSD	COSMIC	22.099	Up-regulation
AGC_PKC_PKCh_PRKCH_ST	P05107	ITGB2	P24723	PRKCH	S591	R586W	586	Missense	distal	-5	no	25.310	23.762	EPSD	COSMIC	22.099	Down-regulation
AGC_PKC_PKCh_PRKCH_ST	P05107	ITGB2	P24723	PRKCH	S591	R595Q	595	Missense	distal	4	no	25.310	27.810	EPSD	COSMIC;GDSC	22.099	Up-regulation
AGC_PKC_PKCh_PRKCH_ST	P05107	ITGB2	P24723	PRKCH	S591	R593H	593	Missense	proximal	2	no	25.310	24.182	EPSD	COSMIC	22.099	Down-regulation
AGC_PKC_PKCh_PRKCH_ST	P05107	ITGB2	P24723	PRKCH	S745	E741Q	741	Missense	distal	-4	no	37.899	37.491	PhosphoSitePlus;EPSD	COSMIC	22.099	Down-regulation
AGC_PKC_PKCh_PRKCH_ST	P05107	ITGB2	P24723	PRKCH	T758	T759A	759	Missense	proximal	1	no	30.507	26.763	EPSD;PhosphoSitePlus	COSMIC;GDSC	22.099	Down-regulation
AGC_PKC_PKCh_PRKCH_ST	P05107	ITGB2	P24723	PRKCH	T758	T759M	759	Missense	proximal	1	no	30.507	25.325	EPSD;PhosphoSitePlus	COSMIC	22.099	Down-regulation
AGC_PKC_PKCh_PRKCH_ST	P05107	ITGB2	P24723	PRKCH	T758	N763K	763	Missense	distal	5	no	30.507	30.163	EPSD;PhosphoSitePlus	COSMIC	22.099	Down-regulation
AGC_PKC_PKCh_PRKCH_ST	P05107	ITGB2	P24723	PRKCH	T758	V761I	761	Missense	distal	3	no	30.507	30.452	EPSD;PhosphoSitePlus	COSMIC	22.099	Down-regulation
AGC_PKC_PKCh_PRKCH_ST	P05107	ITGB2	P24723	PRKCH	T758	S756N	756	Missense	proximal	-2	no	30.507	33.360	EPSD;PhosphoSitePlus	COSMIC	22.099	Up-regulation
AGC_PKC_PKCh_PRKCH_ST	Q06124	PTPN11	P24723	PRKCH	S28	R23K	23	Missense	distal	-5	no	23.957	23.769	EPSD	COSMIC	22.099	Down-regulation
AGC_PKC_PKCh_PRKCH_ST	Q06124	PTPN11	P24723	PRKCH	S28	P33S	33	Missense	distal	5	no	23.957	22.306	EPSD	COSMIC	22.099	Down-regulation
AGC_PKC_PKCh_PRKCH_ST	Q06124	PTPN11	P24723	PRKCH	S28	V25I	25	Missense	distal	-3	no	23.957	23.985	EPSD	COSMIC	22.099	Up-regulation
AGC_PKC_PKCh_PRKCH_ST	Q06124	PTPN11	P24723	PRKCH	S34	P33S	33	Missense	proximal	-1	no	21.799	22.383	EPSD	COSMIC	22.099	Gain
AGC_PKC_PKCh_PRKCH_ST	Q06124	PTPN11	P24723	PRKCH	S140	E139K	139	Missense	proximal	-1	no	25.170	24.931	EPSD	COSMIC	22.099	Down-regulation
AGC_PKC_PKCh_PRKCH_ST	Q06124	PTPN11	P24723	PRKCH	S140	G133D	133	Missense	distal	-7	no	25.170	24.208	EPSD	COSMIC	22.099	Down-regulation
AGC_PKC_PKCh_PRKCH_ST	Q06124	PTPN11	P24723	PRKCH	S140	G133C	133	Missense	distal	-7	no	25.170	22.790	EPSD	COSMIC	22.099	Down-regulation
AGC_PKC_PKCh_PRKCH_ST	Q06124	PTPN11	P24723	PRKCH	S140	R138Q	138	Missense	proximal	-2	no	25.170	20.661	EPSD	COSMIC	22.099	Loss
AGC_PKC_PKCh_PRKCH_ST	Q06124	PTPN11	P24723	PRKCH	S160	G163C	163	Missense	distal	3	no	23.396	24.250	EPSD	COSMIC	22.099	Up-regulation
AGC_PKC_PKCh_PRKCH_ST	Q06124	PTPN11	P24723	PRKCH	S503	M508V	508	Missense	distal	5	no	23.882	24.440	EPSD	COSMIC	22.099	Up-regulation
AGC_PKC_PKCh_PRKCH_ST	Q06124	PTPN11	P24723	PRKCH	S503	R502W	502	Missense	proximal	-1	no	23.882	23.379	EPSD	COSMIC	22.099	Down-regulation
AGC_PKC_PKCh_PRKCH_ST	Q06124	PTPN11	P24723	PRKCH	S503	S506L	506	Missense	distal	3	no	23.882	23.943	EPSD	COSMIC	22.099	Up-regulation
AGC_PKC_PKCh_PRKCH_ST	Q06124	PTPN11	P24723	PRKCH	S503	V509I	509	Missense	distal	6	no	23.882	23.921	EPSD	COSMIC	22.099	Up-regulation
AGC_PKC_PKCh_PRKCH_ST	Q06124	PTPN11	P24723	PRKCH	S503	Q504E	504	Missense	proximal	1	no	23.882	19.832	EPSD	COSMIC	22.099	Loss
AGC_PKC_PKCh_PRKCH_ST	Q06124	PTPN11	P24723	PRKCH	S503	G507V	507	Missense	distal	4	no	23.882	23.452	EPSD	COSMIC	22.099	Down-regulation
AGC_PKC_PKCh_PRKCH_ST	Q06124	PTPN11	P24723	PRKCH	S503	G507R	507	Missense	distal	4	no	23.882	22.875	EPSD	COSMIC	22.099	Down-regulation
AGC_PKC_PKCh_PRKCH_ST	Q06124	PTPN11	P24723	PRKCH	S503	Q510K	510	Missense	distal	7	no	23.882	23.558	EPSD	COSMIC	22.099	Down-regulation
AGC_PKC_PKCh_PRKCH_ST	Q06124	PTPN11	P24723	PRKCH	S503	R505K	505	Missense	proximal	2	no	23.882	22.381	EPSD	COSMIC	22.099	Down-regulation
AGC_PKC_PKCh_PRKCH_ST	Q06124	PTPN11	P24723	PRKCH	S503	S506P	506	Missense	distal	3	no	23.882	23.456	EPSD	COSMIC	22.099	Down-regulation
AGC_PKC_PKCh_PRKCH_ST	Q06124	PTPN11	P24723	PRKCH	S503	G507E	507	Missense	distal	4	no	23.882	26.664	EPSD	COSMIC	22.099	Up-regulation
AGC_PKC_PKCh_PRKCH_ST	Q06124	PTPN11	P24723	PRKCH	S503	G507A	507	Missense	distal	4	no	23.882	24.266	EPSD	COSMIC	22.099	Up-regulation
AGC_PKC_PKCh_PRKCH_ST	Q06124	PTPN11	P24723	PRKCH	S503	R502Q	502	Missense	proximal	-1	no	23.882	23.513	EPSD	COSMIC	22.099	Down-regulation
AGC_PKC_PKCh_PRKCH_ST	Q06124	PTPN11	P24723	PRKCH	S503	Q510P	510	Missense	distal	7	no	23.882	23.338	EPSD	COSMIC	22.099	Down-regulation
AGC_PKC_PKCh_PRKCH_ST	Q06124	PTPN11	P24723	PRKCH	S503	G507W	507	Missense	distal	4	no	23.882	22.059	EPSD	COSMIC	22.099	Loss
AGC_PKC_PKCh_PRKCH_ST	Q06124	PTPN11	P24723	PRKCH	S503	Q510E	510	Missense	distal	7	no	23.882	21.700	EPSD	COSMIC	22.099	Loss
AGC_PKC_PKCh_PRKCH_ST	Q06124	PTPN11	P24723	PRKCH	S503	S506T	506	Missense	distal	3	no	23.882	23.537	EPSD	COSMIC	22.099	Down-regulation
AGC_PKC_PKCh_PRKCH_ST	Q06124	PTPN11	P24723	PRKCH	S503	S506A	506	Missense	distal	3	no	23.882	23.647	EPSD	COSMIC	22.099	Down-regulation
AGC_PKC_PKCh_PRKCH_ST	Q06124	PTPN11	P24723	PRKCH	S503	R502L	502	Missense	proximal	-1	no	23.882	23.927	EPSD	COSMIC	22.099	Up-regulation
AGC_PKC_PKCh_PRKCH_ST	Q06124	PTPN11	P24723	PRKCH	S503	T497I	497	Missense	distal	-6	no	23.882	23.540	EPSD	COSMIC	22.099	Down-regulation
AGC_PKC_PKCh_PRKCH_ST	Q06124	PTPN11	P24723	PRKCH	S503	M508I	508	Missense	distal	5	no	23.882	24.371	EPSD	COSMIC	22.099	Up-regulation
AGC_PKC_PKCh_PRKCH_ST	Q06124	PTPN11	P24723	PRKCH	S503	G507L	507	Missense	distal	4	no	23.882	23.291	EPSD	COSMIC	22.099	Down-regulation
AGC_PKC_PKCh_PRKCH_ST	Q06124	PTPN11	P24723	PRKCH	S503	S503F	503	Missense	central	0	yes	23.882	0.000	EPSD	COSMIC	22.099	Loss
AGC_PKC_PKCh_PRKCH_ST	Q06124	PTPN11	P24723	PRKCH	T547	N548T	548	Missense	proximal	1	no	14.341	22.390	EPSD	COSMIC	22.099	Gain
AGC_PKC_PKCh_PRKCH_ST	Q06124	PTPN11	P24723	PRKCH	S580	D579E	579	Missense	proximal	-1	no	33.107	34.011	EPSD	COSMIC	22.099	Up-regulation
AGC_PKC_PKCh_PRKCH_ST	Q06124	PTPN11	P24723	PRKCH	S580	R582G	582	Missense	proximal	2	no	33.107	31.634	EPSD	COSMIC	22.099	Down-regulation
AGC_PKC_PKCh_PRKCH_ST	Q06124	PTPN11	P24723	PRKCH	S580	V583A	583	Missense	distal	3	no	33.107	32.932	EPSD	COSMIC	22.099	Down-regulation
AGC_PKC_PKCh_PRKCH_ST	Q06124	PTPN11	P24723	PRKCH	S580	V587A	587	Missense	distal	7	no	33.107	31.218	EPSD	COSMIC	22.099	Down-regulation
AGC_PKC_PKCh_PRKCH_ST	Q06124	PTPN11	P24723	PRKCH	S580	S580I	580	Missense	central	0	yes	33.107	0.000	EPSD	COSMIC	22.099	Loss
AGC_PKC_PKCh_PRKCH_ST	Q06124	PTPN11	P24723	PRKCH	S595	Q592H	592	Missense	distal	-3	no	37.845	37.886	EPSD	COSMIC	22.099	Up-regulation
AGC_PKC_PKCh_PRKCH_ST	Q06124	PTPN11	P24723	PRKCH	S595	K594R	594	Missense	proximal	-1	no	37.845	37.771	EPSD	COSMIC	22.099	Down-regulation
AGC_PKC_PKCh_PRKCH_ST	P49841	GSK3B	P24723	PRKCH	T8	S9F	9	Missense	proximal	1	no	24.307	36.054	EPSD	COSMIC	22.099	Up-regulation
AGC_PKC_PKCh_PRKCH_ST	P49841	GSK3B	P24723	PRKCH	T8	S2P	2	Missense	distal	-6	no	24.307	27.989	EPSD	COSMIC	22.099	Up-regulation
AGC_PKC_PKCh_PRKCH_ST	P49841	GSK3B	P24723	PRKCH	S9	S9F	9	Missense	central	0	yes	43.547	0.000	PhosphoSitePlus	COSMIC	22.099	Loss
AGC_PKC_PKCh_PRKCH_ST	P49841	GSK3B	P24723	PRKCH	S9	P16A	16	Missense	distal	7	no	43.547	43.777	PhosphoSitePlus	COSMIC	22.099	Up-regulation
AGC_PKC_PKCh_PRKCH_ST	P49841	GSK3B	P24723	PRKCH	S9	S2P	2	Missense	distal	-7	no	43.547	42.303	PhosphoSitePlus	COSMIC	22.099	Down-regulation
AGC_PKC_PKCh_PRKCH_ST	P49841	GSK3B	P24723	PRKCH	S21	S25C	25	Missense	distal	4	no	23.547	20.039	EPSD	COSMIC	22.099	Loss
AGC_PKC_PKCh_PRKCH_ST	P49841	GSK3B	P24723	PRKCH	S21	P16A	16	Missense	distal	-5	no	23.547	23.615	EPSD	COSMIC	22.099	Up-regulation
AGC_PKC_PKCh_PRKCH_ST	P49841	GSK3B	P24723	PRKCH	S21	A22T	22	Missense	proximal	1	no	23.547	27.291	EPSD	COSMIC	22.099	Up-regulation
AGC_PKC_PKCh_PRKCH_ST	P49841	GSK3B	P24723	PRKCH	S29	D31Y	31	Missense	proximal	2	no	21.727	23.065	EPSD	COSMIC	22.099	Gain
AGC_PKC_PKCh_PRKCH_ST	P49841	GSK3B	P24723	PRKCH	S29	S35R	35	Missense	distal	6	no	21.727	22.526	EPSD	COSMIC	22.099	Gain
AGC_PKC_PKCh_PRKCH_ST	P49841	GSK3B	P24723	PRKCH	S29	A22T	22	Missense	distal	-7	no	21.727	22.370	EPSD	COSMIC	22.099	Gain
AGC_PKC_PKCh_PRKCH_ST	P49841	GSK3B	P24723	PRKCH	S215	Y222C	222	Missense	distal	7	no	24.060	26.454	EPSD	COSMIC	22.099	Up-regulation
AGC_PKC_PKCh_PRKCH_ST	P24723	PRKCH	P24723	PRKCH	S28	S28L	28	Missense	central	0	yes	40.511	0.000	PhosphoSitePlus;EPSD	COSMIC	22.099	Loss
AGC_PKC_PKCh_PRKCH_ST	P24723	PRKCH	P24723	PRKCH	S28	H31R	31	Missense	distal	3	no	40.511	40.423	PhosphoSitePlus;EPSD	COSMIC	22.099	Down-regulation
AGC_PKC_PKCh_PRKCH_ST	P24723	PRKCH	P24723	PRKCH	S32	S28L	28	Missense	distal	-4	no	42.756	43.038	EPSD;PhosphoSitePlus	COSMIC	22.099	Up-regulation
AGC_PKC_PKCh_PRKCH_ST	P24723	PRKCH	P24723	PRKCH	S32	H31R	31	Missense	proximal	-1	no	42.756	43.051	EPSD;PhosphoSitePlus	COSMIC	22.099	Up-regulation
AGC_PKC_PKCh_PRKCH_ST	Q15139	PRKD1	P24723	PRKCH	S223	P227S	227	Missense	distal	4	no	23.139	25.693	EPSD	COSMIC	22.099	Up-regulation
AGC_PKC_PKCh_PRKCH_ST	Q15139	PRKD1	P24723	PRKCH	T224	P227S	227	Missense	distal	3	no	23.132	23.557	EPSD	COSMIC	22.099	Up-regulation
AGC_PKC_PKCh_PRKCH_ST	Q15139	PRKD1	P24723	PRKCH	S379	A373T	373	Missense	distal	-6	no	23.225	23.402	EPSD	COSMIC	22.099	Up-regulation
AGC_PKC_PKCh_PRKCH_ST	Q15139	PRKD1	P24723	PRKCH	S379	Q383P	383	Missense	distal	4	no	23.225	23.409	EPSD	COSMIC	22.099	Up-regulation
AGC_PKC_PKCh_PRKCH_ST	Q15139	PRKD1	P24723	PRKCH	T422	S420F	420	Missense	proximal	-2	no	23.621	25.785	EPSD	COSMIC	22.099	Up-regulation
AGC_PKC_PKCh_PRKCH_ST	Q15139	PRKD1	P24723	PRKCH	S738	G735V	735	Missense	distal	-3	no	42.688	42.739	PhosphoSitePlus;EPSD	COSMIC	22.099	Up-regulation
AGC_PKC_PKCh_PRKCH_ST	Q15139	PRKD1	P24723	PRKCH	S738	V743L	743	Missense	distal	5	no	42.688	41.887	PhosphoSitePlus;EPSD	COSMIC	22.099	Down-regulation
AGC_PKC_PKCh_PRKCH_ST	Q15139	PRKD1	P24723	PRKCH	S738	A731D	731	Missense	distal	-7	no	42.688	42.867	PhosphoSitePlus;EPSD	COSMIC	22.099	Up-regulation
AGC_PKC_PKCh_PRKCH_ST	Q15139	PRKD1	P24723	PRKCH	S742	A748T	748	Missense	distal	6	no	43.278	42.198	EPSD;PhosphoSitePlus	COSMIC	22.099	Down-regulation
AGC_PKC_PKCh_PRKCH_ST	Q15139	PRKD1	P24723	PRKCH	S742	G735V	735	Missense	distal	-7	no	43.278	41.822	EPSD;PhosphoSitePlus	COSMIC	22.099	Down-regulation
AGC_PKC_PKCh_PRKCH_ST	Q15139	PRKD1	P24723	PRKCH	S742	V743L	743	Missense	proximal	1	no	43.278	43.532	EPSD;PhosphoSitePlus	COSMIC	22.099	Up-regulation
AGC_PKC_PKCh_PRKCH_ST	Q15139	PRKD1	P24723	PRKCH	S742	T746I	746	Missense	distal	4	no	43.278	43.016	EPSD;PhosphoSitePlus	COSMIC	22.099	Down-regulation
AGC_PKC_PKCh_PRKCH_ST	Q9BZL6	PRKD2	P24723	PRKCH	S183	N187K	187	Missense	distal	4	no	21.223	22.170	EPSD	COSMIC	22.099	Gain
AGC_PKC_PKCh_PRKCH_ST	Q9BZL6	PRKD2	P24723	PRKCH	S183	S189C	189	Missense	distal	6	no	21.223	23.771	EPSD	COSMIC	22.099	Gain
AGC_PKC_PKCh_PRKCH_ST	Q9BZL6	PRKD2	P24723	PRKCH	S236	S237F	237	Missense	proximal	1	no	12.614	24.361	EPSD	COSMIC	22.099	Gain
AGC_PKC_PKCh_PRKCH_ST	Q9BZL6	PRKD2	P24723	PRKCH	T276	V277I	277	Missense	proximal	1	no	22.532	15.395	EPSD	COSMIC	22.099	Loss
AGC_PKC_PKCh_PRKCH_ST	Q9BZL6	PRKD2	P24723	PRKCH	S362	A361T	361	Missense	proximal	-1	no	23.520	23.302	EPSD	COSMIC	22.099	Down-regulation
AGC_PKC_PKCh_PRKCH_ST	Q9BZL6	PRKD2	P24723	PRKCH	S362	G367V	367	Missense	distal	5	no	23.520	23.267	EPSD	COSMIC	22.099	Down-regulation
AGC_PKC_PKCh_PRKCH_ST	Q9BZL6	PRKD2	P24723	PRKCH	S387	V385E	385	Missense	proximal	-2	no	19.414	22.605	EPSD	COSMIC	22.099	Gain
AGC_PKC_PKCh_PRKCH_ST	Q9BZL6	PRKD2	P24723	PRKCH	S387	T391M	391	Missense	distal	4	no	19.414	22.288	EPSD	COSMIC	22.099	Gain
AGC_PKC_PKCh_PRKCH_ST	Q9BZL6	PRKD2	P24723	PRKCH	T391	T397N	397	Missense	distal	6	no	27.000	30.124	EPSD	COSMIC	22.099	Up-regulation
AGC_PKC_PKCh_PRKCH_ST	Q9BZL6	PRKD2	P24723	PRKCH	T391	R389L	389	Missense	proximal	-2	no	27.000	20.606	EPSD	COSMIC	22.099	Loss
AGC_PKC_PKCh_PRKCH_ST	Q9BZL6	PRKD2	P24723	PRKCH	T391	V385E	385	Missense	distal	-6	no	27.000	29.698	EPSD	COSMIC	22.099	Up-regulation
AGC_PKC_PKCh_PRKCH_ST	Q9BZL6	PRKD2	P24723	PRKCH	T391	Q386K	386	Missense	distal	-5	no	27.000	27.896	EPSD	COSMIC	22.099	Up-regulation
AGC_PKC_PKCh_PRKCH_ST	Q9BZL6	PRKD2	P24723	PRKCH	T391	T391M	391	Missense	central	0	yes	27.000	0.000	EPSD	COSMIC	22.099	Loss
AGC_PKC_PKCh_PRKCH_ST	Q9BZL6	PRKD2	P24723	PRKCH	T397	T397N	397	Missense	central	0	yes	25.216	0.000	EPSD	COSMIC	22.099	Loss
AGC_PKC_PKCh_PRKCH_ST	Q9BZL6	PRKD2	P24723	PRKCH	T397	L399P	399	Missense	proximal	2	no	25.216	24.507	EPSD	COSMIC	22.099	Down-regulation
AGC_PKC_PKCh_PRKCH_ST	Q9BZL6	PRKD2	P24723	PRKCH	T397	T391M	391	Missense	distal	-6	no	25.216	23.725	EPSD	COSMIC	22.099	Down-regulation
AGC_PKC_PKCh_PRKCH_ST	Q9BZL6	PRKD2	P24723	PRKCH	T433	L428I	428	Missense	distal	-5	no	22.862	24.185	EPSD	COSMIC	22.099	Up-regulation
AGC_PKC_PKCh_PRKCH_ST	Q9BZL6	PRKD2	P24723	PRKCH	S529	A523T	523	Missense	distal	-6	no	24.008	24.185	EPSD	COSMIC;GDSC	22.099	Up-regulation
AGC_PKC_PKCh_PRKCH_ST	Q9BZL6	PRKD2	P24723	PRKCH	S706	F707L	707	Missense	proximal	1	no	43.845	40.364	EPSD;PhosphoSitePlus	COSMIC	22.099	Down-regulation
AGC_PKC_PKCh_PRKCH_ST	Q9BZL6	PRKD2	P24723	PRKCH	S706	A699V	699	Missense	distal	-7	no	43.845	43.531	EPSD;PhosphoSitePlus	COSMIC	22.099	Down-regulation
AGC_PKC_PKCh_PRKCH_ST	Q9BZL6	PRKD2	P24723	PRKCH	S706	G703D	703	Missense	distal	-3	no	43.845	43.950	EPSD;PhosphoSitePlus	COSMIC	22.099	Up-regulation
AGC_PKC_PKCh_PRKCH_ST	Q9BZL6	PRKD2	P24723	PRKCH	S706	R700H	700	Missense	distal	-6	no	43.845	42.865	EPSD;PhosphoSitePlus	COSMIC;CCLE	22.099	Down-regulation
AGC_PKC_PKCh_PRKCH_ST	Q9BZL6	PRKD2	P24723	PRKCH	S706	G713R	713	Missense	distal	7	no	43.845	43.152	EPSD;PhosphoSitePlus	COSMIC	22.099	Down-regulation
AGC_PKC_PKCh_PRKCH_ST	Q9BZL6	PRKD2	P24723	PRKCH	S706	G713E	713	Missense	distal	7	no	43.845	41.362	EPSD;PhosphoSitePlus	COSMIC	22.099	Down-regulation
AGC_PKC_PKCh_PRKCH_ST	Q9BZL6	PRKD2	P24723	PRKCH	S710	F707L	707	Missense	distal	-3	no	43.969	44.042	EPSD;PhosphoSitePlus	COSMIC	22.099	Up-regulation
AGC_PKC_PKCh_PRKCH_ST	Q9BZL6	PRKD2	P24723	PRKCH	S710	G703D	703	Missense	distal	-7	no	43.969	43.007	EPSD;PhosphoSitePlus	COSMIC	22.099	Down-regulation
AGC_PKC_PKCh_PRKCH_ST	Q9BZL6	PRKD2	P24723	PRKCH	S710	G713R	713	Missense	distal	3	no	43.969	43.665	EPSD;PhosphoSitePlus	COSMIC	22.099	Down-regulation
AGC_PKC_PKCh_PRKCH_ST	Q9BZL6	PRKD2	P24723	PRKCH	S710	G713E	713	Missense	distal	3	no	43.969	43.669	EPSD;PhosphoSitePlus	COSMIC	22.099	Down-regulation
AGC_PKC_PKCh_PRKCH_ST	Q9BZL6	PRKD2	P24723	PRKCH	S876	G870E	870	Missense	distal	-6	no	36.640	37.883	PhosphoSitePlus;EPSD	COSMIC	22.099	Up-regulation
AGC_PKC_PKCh_PRKCH_ST	Q9BZL6	PRKD2	P24723	PRKCH	S876	S876G	876	Missense	central	0	yes	36.640	0.000	PhosphoSitePlus;EPSD	COSMIC	22.099	Loss
AGC_PKC_PKCh_PRKCH_ST	Q9BZL6	PRKD2	P24723	PRKCH	S876	G870R	870	Missense	distal	-6	no	36.640	38.997	PhosphoSitePlus;EPSD	COSMIC	22.099	Up-regulation
AGC_PKC_PKCh_PRKCH_ST	Q9BZL6	PRKD2	P24723	PRKCH	S876	A872V	872	Missense	distal	-4	no	36.640	36.485	PhosphoSitePlus;EPSD	COSMIC	22.099	Down-regulation
AGC_PKC_PKCh_PRKCH_ST	P09211	GSTP1	P24723	PRKCH	S185	G182R	182	Missense	distal	-3	no	39.461	39.481	PhosphoSitePlus;EPSD	COSMIC	22.099	Up-regulation
AGC_PKC_PKCh_PRKCH_ST	P09211	GSTP1	P24723	PRKCH	S185	S185R	185	Missense	central	0	yes	39.461	0.000	PhosphoSitePlus;EPSD	COSMIC	22.099	Loss
AGC_PKC_PKCh_PRKCH_ST	P09211	GSTP1	P24723	PRKCH	S185	P188L	188	Missense	distal	3	no	39.461	39.948	PhosphoSitePlus;EPSD	COSMIC	22.099	Up-regulation
AGC_PKC_PKCh_PRKCH_ST	P49840	GSK3A	P24723	PRKCH	S52	A51P	51	Missense	proximal	-1	no	25.404	24.755	EPSD	COSMIC	22.099	Down-regulation
AGC_PKC_PKCh_PRKCH_ST	P49840	GSK3A	P24723	PRKCH	S52	G49V	49	Missense	distal	-3	no	25.404	25.455	EPSD	COSMIC	22.099	Up-regulation
AGC_PKC_PKCh_PRKCH_ST	P49840	GSK3A	P24723	PRKCH	S85	A82T	82	Missense	distal	-3	no	23.563	23.559	EPSD	COSMIC	22.099	Down-regulation
AGC_PKC_PKCh_PRKCH_ST	P49840	GSK3A	P24723	PRKCH	S97	V104I	104	Missense	distal	7	no	24.257	23.043	EPSD	COSMIC;GDSC;CCLE	22.099	Down-regulation
AGC_PKC_PKCh_PRKCH_ST	P49840	GSK3A	P24723	PRKCH	S129	G128S	128	Missense	proximal	-1	no	21.849	22.138	EPSD	COSMIC	22.099	Gain
AGC_PKC_PKCh_PRKCH_ST	P49840	GSK3A	P24723	PRKCH	S129	I122M	122	Missense	distal	-7	no	21.849	23.266	EPSD	COSMIC	22.099	Gain
AGC_PKC_PKCh_PRKCH_ST	P49840	GSK3A	P24723	PRKCH	S278	Y285C	285	Missense	distal	7	no	21.852	24.247	EPSD	COSMIC	22.099	Gain
AGC_PKC_PKCh_PRKCH_ST	P49840	GSK3A	P24723	PRKCH	S401	C398Y	398	Missense	distal	-3	no	24.798	24.680	EPSD	COSMIC	22.099	Down-regulation
AGC_PKC_PKCh_PRKCH_ST	P49840	GSK3A	P24723	PRKCH	S401	H400R	400	Missense	proximal	-1	no	24.798	25.093	EPSD	COSMIC	22.099	Up-regulation
AGC_PKC_PKCh_PRKCH_ST	P49840	GSK3A	P24723	PRKCH	S401	H400L	400	Missense	proximal	-1	no	24.798	25.139	EPSD	COSMIC	22.099	Up-regulation
AGC_PKC_PKCh_PRKCH_ST	P49840	GSK3A	P24723	PRKCH	S401	D404Y	404	Missense	distal	3	no	24.798	24.473	EPSD	COSMIC	22.099	Down-regulation
AGC_PKC_PKCh_PRKCH_ST	P49840	GSK3A	P24723	PRKCH	S401	A399V	399	Missense	proximal	-2	no	24.798	25.426	EPSD	COSMIC	22.099	Up-regulation
Other_PLK_PLK1_PLK1_ST	Q14203	DCTN1	P53350	PLK1	S23	R28P	28	Missense	distal	5	no	11.515	11.558	EPSD	COSMIC	10.919	Up-regulation
Other_PLK_PLK1_PLK1_ST	Q14203	DCTN1	P53350	PLK1	S23	R28Q	28	Missense	distal	5	no	11.515	10.720	EPSD	COSMIC	10.919	Loss
Other_PLK_PLK1_PLK1_ST	Q14203	DCTN1	P53350	PLK1	S111	D110N	110	Missense	proximal	-1	no	11.527	10.593	EPSD	COSMIC	10.919	Loss
Other_PLK_PLK1_PLK1_ST	Q14203	DCTN1	P53350	PLK1	S111	S112R	112	Missense	proximal	1	no	11.527	10.362	EPSD	COSMIC	10.919	Loss
Other_PLK_PLK1_PLK1_ST	Q14203	DCTN1	P53350	PLK1	S111	T108I	108	Missense	distal	-3	no	11.527	11.549	EPSD	COSMIC	10.919	Up-regulation
Other_PLK_PLK1_PLK1_ST	Q14203	DCTN1	P53350	PLK1	S179	G176V	176	Missense	distal	-3	no	14.194	13.545	PhosphoSitePlus	COSMIC	10.919	Down-regulation
Other_PLK_PLK1_PLK1_ST	Q14203	DCTN1	P53350	PLK1	S179	A173V	173	Missense	distal	-6	no	14.194	13.955	PhosphoSitePlus	COSMIC	10.919	Down-regulation
Other_PLK_PLK1_PLK1_ST	Q14203	DCTN1	P53350	PLK1	T336	R331L	331	Missense	distal	-5	no	13.074	13.054	EPSD	COSMIC	10.919	Down-regulation
Other_PLK_PLK1_PLK1_ST	Q14203	DCTN1	P53350	PLK1	T336	E334K	334	Missense	proximal	-2	no	13.074	10.197	EPSD	COSMIC	10.919	Loss
Other_PLK_PLK1_PLK1_ST	Q14203	DCTN1	P53350	PLK1	S417	E414K	414	Missense	distal	-3	no	10.563	11.103	EPSD	COSMIC	10.919	Gain
Other_PLK_PLK1_PLK1_ST	Q14203	DCTN1	P53350	PLK1	S417	R411H	411	Missense	distal	-6	no	10.563	11.022	EPSD	COSMIC	10.919	Gain
Other_PLK_PLK1_PLK1_ST	Q14203	DCTN1	P53350	PLK1	S541	A540S	540	Missense	proximal	-1	no	11.150	11.617	EPSD	COSMIC	10.919	Up-regulation
Other_PLK_PLK1_PLK1_ST	Q14203	DCTN1	P53350	PLK1	S595	P599S	599	Missense	distal	4	no	11.237	11.558	EPSD	COSMIC	10.919	Up-regulation
Other_PLK_PLK1_PLK1_ST	Q14203	DCTN1	P53350	PLK1	S687	G686E	686	Missense	proximal	-1	no	9.948	11.741	EPSD	COSMIC	10.919	Gain
Other_PLK_PLK1_PLK1_ST	Q14203	DCTN1	P53350	PLK1	S687	G686D	686	Missense	proximal	-1	no	9.948	12.538	EPSD	COSMIC	10.919	Gain
Other_PLK_PLK1_PLK1_ST	Q14203	DCTN1	P53350	PLK1	S693	A694V	694	Missense	proximal	1	no	9.493	10.931	EPSD	COSMIC	10.919	Gain
Other_PLK_PLK1_PLK1_ST	Q14203	DCTN1	P53350	PLK1	S974	R972P	972	Missense	proximal	-2	no	12.138	11.780	EPSD	COSMIC	10.919	Down-regulation
Other_PLK_PLK1_PLK1_ST	Q14203	DCTN1	P53350	PLK1	S974	A969V	969	Missense	distal	-5	no	12.138	12.066	EPSD	COSMIC	10.919	Down-regulation
Other_PLK_PLK1_PLK1_ST	Q14203	DCTN1	P53350	PLK1	S1112	K1115R	1115	Missense	distal	3	no	13.157	13.060	EPSD	COSMIC	10.919	Down-regulation
Other_PLK_PLK1_PLK1_ST	Q14203	DCTN1	P53350	PLK1	S1112	H1109Y	1109	Missense	distal	-3	no	13.157	13.466	EPSD	COSMIC;GDSC;CCLE	10.919	Up-regulation
Other_PLK_PLK1_PLK1_ST	Q14203	DCTN1	P53350	PLK1	S1112	S1105F	1105	Missense	distal	-7	no	13.157	12.700	EPSD	COSMIC	10.919	Down-regulation
Other_PLK_PLK1_PLK1_ST	Q14203	DCTN1	P53350	PLK1	T1158	Q1154E	1154	Missense	distal	-4	no	11.016	11.285	EPSD	COSMIC	10.919	Up-regulation
Other_PLK_PLK1_PLK1_ST	Q14203	DCTN1	P53350	PLK1	T1158	L1159S	1159	Missense	proximal	1	no	11.016	9.049	EPSD	COSMIC	10.919	Loss
Other_PLK_PLK1_PLK1_ST	O60563	CCNT1	P53350	PLK1	S22	R25C	25	Missense	distal	3	no	12.291	12.351	EPSD	COSMIC	10.919	Up-regulation
Other_PLK_PLK1_PLK1_ST	O60563	CCNT1	P53350	PLK1	S363	H362R	362	Missense	proximal	-1	no	11.051	10.054	EPSD	COSMIC	10.919	Loss
Other_PLK_PLK1_PLK1_ST	O60563	CCNT1	P53350	PLK1	S499	E497G	497	Missense	proximal	-2	no	12.128	9.200	EPSD	COSMIC	10.919	Loss
Other_PLK_PLK1_PLK1_ST	O60563	CCNT1	P53350	PLK1	S549	D544Y	544	Missense	distal	-5	no	11.229	11.084	EPSD	COSMIC	10.919	Down-regulation
Other_PLK_PLK1_PLK1_ST	O60563	CCNT1	P53350	PLK1	S549	S552R	552	Missense	distal	3	no	11.229	11.105	EPSD	COSMIC	10.919	Down-regulation
Other_PLK_PLK1_PLK1_ST	O60563	CCNT1	P53350	PLK1	S560	T558A	558	Missense	proximal	-2	no	12.630	13.249	EPSD	COSMIC	10.919	Up-regulation
Other_PLK_PLK1_PLK1_ST	O60563	CCNT1	P53350	PLK1	S560	S567A	567	Missense	distal	7	no	12.630	12.655	EPSD	COSMIC	10.919	Up-regulation
Other_PLK_PLK1_PLK1_ST	O60563	CCNT1	P53350	PLK1	S560	S564F	564	Missense	distal	4	no	12.630	11.816	EPSD	COSMIC;GDSC	10.919	Down-regulation
Other_PLK_PLK1_PLK1_ST	O60563	CCNT1	P53350	PLK1	S564	T558A	558	Missense	distal	-6	no	13.753	13.821	PhosphoSitePlus	COSMIC	10.919	Up-regulation
Other_PLK_PLK1_PLK1_ST	O60563	CCNT1	P53350	PLK1	S564	S567A	567	Missense	distal	3	no	13.753	13.577	PhosphoSitePlus	COSMIC	10.919	Down-regulation
Other_PLK_PLK1_PLK1_ST	O60563	CCNT1	P53350	PLK1	S564	S568F	568	Missense	distal	4	no	13.753	12.939	PhosphoSitePlus	COSMIC	10.919	Down-regulation
Other_PLK_PLK1_PLK1_ST	O60563	CCNT1	P53350	PLK1	S564	S564F	564	Missense	central	0	yes	13.753	0.000	PhosphoSitePlus	COSMIC;GDSC	10.919	Loss
Other_PLK_PLK1_PLK1_ST	O60563	CCNT1	P53350	PLK1	S567	S568F	568	Missense	proximal	1	no	8.097	11.145	EPSD	COSMIC	10.919	Gain
Other_PLK_PLK1_PLK1_ST	O60563	CCNT1	P53350	PLK1	S577	P576T	576	Missense	proximal	-1	no	11.112	11.538	EPSD	COSMIC	10.919	Up-regulation
Other_PLK_PLK1_PLK1_ST	O60563	CCNT1	P53350	PLK1	T580	P576T	576	Missense	distal	-4	no	11.250	11.010	EPSD	COSMIC	10.919	Down-regulation
Other_PLK_PLK1_PLK1_ST	Q9Y2I6	NINL	P53350	PLK1	S448	E455K	455	Missense	distal	7	no	11.419	11.492	EPSD	COSMIC	10.919	Up-regulation
Other_PLK_PLK1_PLK1_ST	Q9Y2I6	NINL	P53350	PLK1	S606	A612V	612	Missense	distal	6	no	12.804	12.628	EPSD	COSMIC	10.919	Down-regulation
Other_PLK_PLK1_PLK1_ST	Q9Y2I6	NINL	P53350	PLK1	S686	V689D	689	Missense	distal	3	no	12.596	12.690	EPSD;PhosphoSitePlus	COSMIC	10.919	Up-regulation
Other_PLK_PLK1_PLK1_ST	Q9Y2I6	NINL	P53350	PLK1	T1094	D1099N	1099	Missense	distal	5	no	11.828	11.075	EPSD	COSMIC	10.919	Down-regulation
Other_PLK_PLK1_PLK1_ST	Q9Y2I6	NINL	P53350	PLK1	T1094	S1090C	1090	Missense	distal	-4	no	11.828	11.016	EPSD	COSMIC	10.919	Down-regulation
Other_PLK_PLK1_PLK1_ST	Q9Y2I6	NINL	P53350	PLK1	S1267	A1273V	1273	Missense	distal	6	no	13.812	13.637	EPSD	COSMIC	10.919	Down-regulation
Other_PLK_PLK1_PLK1_ST	Q9Y2I6	NINL	P53350	PLK1	S1267	R1264C	1264	Missense	distal	-3	no	13.812	13.016	EPSD	COSMIC	10.919	Down-regulation
Other_PLK_PLK1_PLK1_ST	P60484	PTEN	P53350	PLK1	S227	Y225D	225	Missense	proximal	-2	no	10.313	11.855	EPSD	COSMIC	10.919	Gain
Other_PLK_PLK1_PLK1_ST	P60484	PTEN	P53350	PLK1	S227	T232P	232	Missense	distal	5	no	10.313	11.305	EPSD	COSMIC	10.919	Gain
Other_PLK_PLK1_PLK1_ST	P60484	PTEN	P53350	PLK1	T319	T321I	321	Missense	proximal	2	no	10.146	11.207	EPSD	COSMIC	10.919	Gain
Other_PLK_PLK1_PLK1_ST	P60484	PTEN	P53350	PLK1	S338	N334D	334	Missense	distal	-4	no	10.952	10.893	EPSD	COSMIC	10.919	Loss
Other_PLK_PLK1_PLK1_ST	P60484	PTEN	P53350	PLK1	S338	F337L	337	Missense	proximal	-1	no	10.952	11.031	EPSD	COSMIC	10.919	Up-regulation
Other_PLK_PLK1_PLK1_ST	P60484	PTEN	P53350	PLK1	S338	F341L	341	Missense	distal	3	no	10.952	10.746	EPSD	COSMIC	10.919	Loss
Other_PLK_PLK1_PLK1_ST	P60484	PTEN	P53350	PLK1	S338	P339S	339	Missense	proximal	1	no	10.952	9.831	EPSD	COSMIC	10.919	Loss
Other_PLK_PLK1_PLK1_ST	P60484	PTEN	P53350	PLK1	S338	S338Y	338	Missense	central	0	yes	10.952	0.000	EPSD	COSMIC	10.919	Loss
Other_PLK_PLK1_PLK1_ST	P60484	PTEN	P53350	PLK1	S338	F341I	341	Missense	distal	3	no	10.952	10.922	EPSD	COSMIC	10.919	Down-regulation
Other_PLK_PLK1_PLK1_ST	P60484	PTEN	P53350	PLK1	S338	F341Y	341	Missense	distal	3	no	10.952	10.712	EPSD	COSMIC	10.919	Loss
Other_PLK_PLK1_PLK1_ST	P60484	PTEN	P53350	PLK1	S338	P339L	339	Missense	proximal	1	no	10.952	11.798	EPSD	COSMIC	10.919	Up-regulation
Other_PLK_PLK1_PLK1_ST	P60484	PTEN	P53350	PLK1	S338	N334S	334	Missense	distal	-4	no	10.952	11.087	EPSD	COSMIC	10.919	Up-regulation
Other_PLK_PLK1_PLK1_ST	P60484	PTEN	P53350	PLK1	S338	N334Y	334	Missense	distal	-4	no	10.952	10.400	EPSD	COSMIC	10.919	Loss
Other_PLK_PLK1_PLK1_ST	P60484	PTEN	P53350	PLK1	S338	K344R	344	Missense	distal	6	no	10.952	10.593	EPSD	COSMIC	10.919	Loss
Other_PLK_PLK1_PLK1_ST	P60484	PTEN	P53350	PLK1	S338	D331H	331	Missense	distal	-7	no	10.952	11.185	EPSD	COSMIC	10.919	Up-regulation
Other_PLK_PLK1_PLK1_ST	P60484	PTEN	P53350	PLK1	S338	D331G	331	Missense	distal	-7	no	10.952	10.606	EPSD	COSMIC	10.919	Loss
Other_PLK_PLK1_PLK1_ST	P60484	PTEN	P53350	PLK1	S338	Y336C	336	Missense	proximal	-2	no	10.952	7.442	EPSD	COSMIC	10.919	Loss
Other_PLK_PLK1_PLK1_ST	P60484	PTEN	P53350	PLK1	S338	V343G	343	Missense	distal	5	no	10.952	11.307	EPSD	COSMIC	10.919	Up-regulation
Other_PLK_PLK1_PLK1_ST	P60484	PTEN	P53350	PLK1	S338	S338C	338	Missense	central	0	yes	10.952	0.000	EPSD	COSMIC	10.919	Loss
Other_PLK_PLK1_PLK1_ST	P60484	PTEN	P53350	PLK1	S338	Y336F	336	Missense	proximal	-2	no	10.952	8.284	EPSD	COSMIC	10.919	Loss
Other_PLK_PLK1_PLK1_ST	P60484	PTEN	P53350	PLK1	S338	A333V	333	Missense	distal	-5	no	10.952	10.880	EPSD	COSMIC	10.919	Loss
Other_PLK_PLK1_PLK1_ST	P60484	PTEN	P53350	PLK1	S355	P357L	357	Missense	proximal	2	no	9.484	11.032	EPSD	COSMIC	10.919	Gain
Other_PLK_PLK1_PLK1_ST	P60484	PTEN	P53350	PLK1	S355	P357S	357	Missense	proximal	2	no	9.484	10.960	EPSD	COSMIC	10.919	Gain
Other_PLK_PLK1_PLK1_ST	P60484	PTEN	P53350	PLK1	S360	P357L	357	Missense	distal	-3	no	10.219	11.410	EPSD	COSMIC	10.919	Gain
Other_PLK_PLK1_PLK1_ST	P60484	PTEN	P53350	PLK1	S360	S361N	361	Missense	proximal	1	no	10.219	10.959	EPSD	COSMIC	10.919	Gain
Other_PLK_PLK1_PLK1_ST	P60484	PTEN	P53350	PLK1	S362	V369G	369	Missense	distal	7	no	11.719	11.670	EPSD	COSMIC	10.919	Down-regulation
Other_PLK_PLK1_PLK1_ST	P60484	PTEN	P53350	PLK1	S362	P357Q	357	Missense	distal	-5	no	11.719	11.402	EPSD	COSMIC	10.919	Down-regulation
Other_PLK_PLK1_PLK1_ST	P60484	PTEN	P53350	PLK1	S362	V365I	365	Missense	distal	3	no	11.719	11.597	EPSD	COSMIC	10.919	Down-regulation
Other_PLK_PLK1_PLK1_ST	P60484	PTEN	P53350	PLK1	S362	P357L	357	Missense	distal	-5	no	11.719	12.121	EPSD	COSMIC	10.919	Up-regulation
Other_PLK_PLK1_PLK1_ST	P60484	PTEN	P53350	PLK1	S362	P357S	357	Missense	distal	-5	no	11.719	11.457	EPSD	COSMIC	10.919	Down-regulation
Other_PLK_PLK1_PLK1_ST	P60484	PTEN	P53350	PLK1	S362	S364C	364	Missense	proximal	2	no	11.719	10.747	EPSD	COSMIC	10.919	Loss
Other_PLK_PLK1_PLK1_ST	P60484	PTEN	P53350	PLK1	S362	S361N	361	Missense	proximal	-1	no	11.719	11.579	EPSD	COSMIC	10.919	Down-regulation
Other_PLK_PLK1_PLK1_ST	P60484	PTEN	P53350	PLK1	S362	S355L	355	Missense	distal	-7	no	11.719	11.415	EPSD	COSMIC	10.919	Down-regulation
Other_PLK_PLK1_PLK1_ST	P60484	PTEN	P53350	PLK1	S362	E358D	358	Missense	distal	-4	no	11.719	11.535	EPSD	COSMIC	10.919	Down-regulation
Other_PLK_PLK1_PLK1_ST	P60484	PTEN	P53350	PLK1	T366	V365I	365	Missense	proximal	-1	no	10.132	11.106	EPSD	COSMIC	10.919	Gain
Other_PLK_PLK1_PLK1_ST	P60484	PTEN	P53350	PLK1	S380	D375N	375	Missense	distal	-5	no	11.480	11.184	PhosphoSitePlus;EPSD	COSMIC	10.919	Down-regulation
Other_PLK_PLK1_PLK1_ST	P60484	PTEN	P53350	PLK1	S380	T383I	383	Missense	distal	3	no	11.480	11.646	PhosphoSitePlus;EPSD	COSMIC	10.919	Up-regulation
Other_PLK_PLK1_PLK1_ST	P60484	PTEN	P53350	PLK1	S380	D384N	384	Missense	distal	4	no	11.480	11.241	PhosphoSitePlus;EPSD	COSMIC	10.919	Down-regulation
Other_PLK_PLK1_PLK1_ST	P60484	PTEN	P53350	PLK1	S380	T382S	382	Missense	proximal	2	no	11.480	12.120	PhosphoSitePlus;EPSD	COSMIC	10.919	Up-regulation
Other_PLK_PLK1_PLK1_ST	P60484	PTEN	P53350	PLK1	S380	D384G	384	Missense	distal	4	no	11.480	11.392	PhosphoSitePlus;EPSD	COSMIC	10.919	Down-regulation
Other_PLK_PLK1_PLK1_ST	P60484	PTEN	P53350	PLK1	T382	D375N	375	Missense	distal	-7	no	12.112	12.252	EPSD;PhosphoSitePlus	COSMIC	10.919	Up-regulation
Other_PLK_PLK1_PLK1_ST	P60484	PTEN	P53350	PLK1	T382	T383I	383	Missense	proximal	1	no	12.112	13.279	EPSD;PhosphoSitePlus	COSMIC	10.919	Up-regulation
Other_PLK_PLK1_PLK1_ST	P60484	PTEN	P53350	PLK1	T382	E388K	388	Missense	distal	6	no	12.112	12.043	EPSD;PhosphoSitePlus	COSMIC	10.919	Down-regulation
Other_PLK_PLK1_PLK1_ST	P60484	PTEN	P53350	PLK1	T382	D384N	384	Missense	proximal	2	no	12.112	12.327	EPSD;PhosphoSitePlus	COSMIC	10.919	Up-regulation
Other_PLK_PLK1_PLK1_ST	P60484	PTEN	P53350	PLK1	T382	D384G	384	Missense	proximal	2	no	12.112	10.533	EPSD;PhosphoSitePlus	COSMIC	10.919	Loss
Other_PLK_PLK1_PLK1_ST	P60484	PTEN	P53350	PLK1	T383	T383I	383	Missense	central	0	yes	14.176	0.000	EPSD;PhosphoSitePlus	COSMIC	10.919	Loss
Other_PLK_PLK1_PLK1_ST	P60484	PTEN	P53350	PLK1	T383	E388K	388	Missense	distal	5	no	14.176	14.187	EPSD;PhosphoSitePlus	COSMIC	10.919	Up-regulation
Other_PLK_PLK1_PLK1_ST	P60484	PTEN	P53350	PLK1	T383	D384N	384	Missense	proximal	1	no	14.176	13.981	EPSD;PhosphoSitePlus	COSMIC	10.919	Down-regulation
Other_PLK_PLK1_PLK1_ST	P60484	PTEN	P53350	PLK1	T383	T382S	382	Missense	proximal	-1	no	14.176	14.924	EPSD;PhosphoSitePlus	COSMIC	10.919	Up-regulation
Other_PLK_PLK1_PLK1_ST	P60484	PTEN	P53350	PLK1	T383	D384G	384	Missense	proximal	1	no	14.176	14.178	EPSD;PhosphoSitePlus	COSMIC	10.919	Up-regulation
Other_PLK_PLK1_PLK1_ST	P30305	CDC25B	P53350	PLK1	S50	A47P	47	Missense	distal	-3	no	13.331	12.391	EPSD;PhosphoSitePlus	COSMIC	10.919	Down-regulation
Other_PLK_PLK1_PLK1_ST	P30305	CDC25B	P53350	PLK1	S50	P51L	51	Missense	proximal	1	no	13.331	14.177	EPSD;PhosphoSitePlus	COSMIC	10.919	Up-regulation
Other_PLK_PLK1_PLK1_ST	P30305	CDC25B	P53350	PLK1	S50	Q57R	57	Missense	distal	7	no	13.331	13.317	EPSD;PhosphoSitePlus	COSMIC	10.919	Down-regulation
Other_PLK_PLK1_PLK1_ST	P30305	CDC25B	P53350	PLK1	S50	A48T	48	Missense	proximal	-2	no	13.331	12.713	EPSD;PhosphoSitePlus	COSMIC	10.919	Down-regulation
Other_PLK_PLK1_PLK1_ST	P30305	CDC25B	P53350	PLK1	T58	P51L	51	Missense	distal	-7	no	12.465	12.370	EPSD;PhosphoSitePlus	COSMIC	10.919	Down-regulation
Other_PLK_PLK1_PLK1_ST	P30305	CDC25B	P53350	PLK1	T58	Q57R	57	Missense	proximal	-1	no	12.465	11.861	EPSD;PhosphoSitePlus	COSMIC	10.919	Down-regulation
Other_PLK_PLK1_PLK1_ST	P30305	CDC25B	P53350	PLK1	T127	A124E	124	Missense	distal	-3	no	13.080	12.389	PhosphoSitePlus;EPSD	COSMIC	10.919	Down-regulation
Other_PLK_PLK1_PLK1_ST	P30305	CDC25B	P53350	PLK1	T127	Q130R	130	Missense	distal	3	no	13.080	12.884	PhosphoSitePlus;EPSD	COSMIC	10.919	Down-regulation
Other_PLK_PLK1_PLK1_ST	P30305	CDC25B	P53350	PLK1	T127	I132V	132	Missense	distal	5	no	13.080	12.611	PhosphoSitePlus;EPSD	COSMIC;GDSC;CCLE	10.919	Down-regulation
Other_PLK_PLK1_PLK1_ST	P30305	CDC25B	P53350	PLK1	T127	T127M	127	Missense	central	0	yes	13.080	0.000	PhosphoSitePlus;EPSD	COSMIC	10.919	Loss
Other_PLK_PLK1_PLK1_ST	P30305	CDC25B	P53350	PLK1	T167	V162L	162	Missense	distal	-5	no	12.471	12.924	EPSD;PhosphoSitePlus	COSMIC	10.919	Up-regulation
Other_PLK_PLK1_PLK1_ST	P30305	CDC25B	P53350	PLK1	S229	S230F	230	Missense	proximal	1	no	8.297	11.346	EPSD	COSMIC	10.919	Gain
Other_PLK_PLK1_PLK1_ST	P30305	CDC25B	P53350	PLK1	T265	E262G	262	Missense	distal	-3	no	10.435	11.377	EPSD;PhosphoSitePlus	COSMIC	10.919	Gain
Other_PLK_PLK1_PLK1_ST	P30305	CDC25B	P53350	PLK1	S291	P287S	287	Missense	distal	-4	no	13.114	13.236	EPSD;PhosphoSitePlus	COSMIC;GDSC;CCLE	10.919	Up-regulation
Other_PLK_PLK1_PLK1_ST	P30305	CDC25B	P53350	PLK1	S291	P296T	296	Missense	distal	5	no	13.114	12.122	EPSD;PhosphoSitePlus	COSMIC	10.919	Down-regulation
Other_PLK_PLK1_PLK1_ST	P30305	CDC25B	P53350	PLK1	S323	P325L	325	Missense	proximal	2	no	9.707	11.255	EPSD	COSMIC	10.919	Gain
Other_PLK_PLK1_PLK1_ST	P30305	CDC25B	P53350	PLK1	S375	S373N	373	Missense	proximal	-2	no	9.651	11.061	EPSD;PhosphoSitePlus	COSMIC	10.919	Gain
Other_PLK_PLK1_PLK1_ST	P30305	CDC25B	P53350	PLK1	S397	A399V	399	Missense	proximal	2	no	13.968	14.412	EPSD;PhosphoSitePlus	COSMIC	10.919	Up-regulation
Other_PLK_PLK1_PLK1_ST	P30305	CDC25B	P53350	PLK1	S465	R461G	461	Missense	distal	-4	no	12.264	12.177	EPSD;PhosphoSitePlus	COSMIC	10.919	Down-regulation
Other_PLK_PLK1_PLK1_ST	P30305	CDC25B	P53350	PLK1	S465	E464G	464	Missense	proximal	-1	no	12.264	10.471	EPSD;PhosphoSitePlus	COSMIC	10.919	Loss
Other_PLK_PLK1_PLK1_ST	P30305	CDC25B	P53350	PLK1	S465	E464K	464	Missense	proximal	-1	no	12.264	11.693	EPSD;PhosphoSitePlus	COSMIC	10.919	Down-regulation
Other_PLK_PLK1_PLK1_ST	P30305	CDC25B	P53350	PLK1	S465	R461H	461	Missense	distal	-4	no	12.264	12.565	EPSD;PhosphoSitePlus	COSMIC;GDSC;CCLE	10.919	Up-regulation
Other_PLK_PLK1_PLK1_ST	P30305	CDC25B	P53350	PLK1	S465	A463T	463	Missense	proximal	-2	no	12.264	11.645	EPSD;PhosphoSitePlus	COSMIC	10.919	Down-regulation
Other_PLK_PLK1_PLK1_ST	P30305	CDC25B	P53350	PLK1	S465	K469R	469	Missense	distal	4	no	12.264	11.704	EPSD;PhosphoSitePlus	COSMIC	10.919	Down-regulation
Other_PLK_PLK1_PLK1_ST	P30305	CDC25B	P53350	PLK1	S470	E464G	464	Missense	distal	-6	no	11.498	10.833	EPSD	COSMIC	10.919	Loss
Other_PLK_PLK1_PLK1_ST	P30305	CDC25B	P53350	PLK1	S470	E464K	464	Missense	distal	-6	no	11.498	10.924	EPSD	COSMIC	10.919	Down-regulation
Other_PLK_PLK1_PLK1_ST	P30305	CDC25B	P53350	PLK1	S470	L477P	477	Missense	distal	7	no	11.498	11.527	EPSD	COSMIC	10.919	Up-regulation
Other_PLK_PLK1_PLK1_ST	P30305	CDC25B	P53350	PLK1	S470	A473V	473	Missense	distal	3	no	11.498	11.826	EPSD	COSMIC	10.919	Up-regulation
Other_PLK_PLK1_PLK1_ST	P30305	CDC25B	P53350	PLK1	S470	A463T	463	Missense	distal	-7	no	11.498	11.843	EPSD	COSMIC	10.919	Up-regulation
Other_PLK_PLK1_PLK1_ST	P30305	CDC25B	P53350	PLK1	S470	K469R	469	Missense	proximal	-1	no	11.498	11.136	EPSD	COSMIC	10.919	Down-regulation
Other_PLK_PLK1_PLK1_ST	P30305	CDC25B	P53350	PLK1	S513	R506L	506	Missense	distal	-7	no	11.334	11.526	EPSD;PhosphoSitePlus	COSMIC	10.919	Up-regulation
Other_PLK_PLK1_PLK1_ST	P30305	CDC25B	P53350	PLK1	S513	R506W	506	Missense	distal	-7	no	11.334	11.920	EPSD;PhosphoSitePlus	COSMIC	10.919	Up-regulation
Other_PLK_PLK1_PLK1_ST	P30305	CDC25B	P53350	PLK1	S513	P517H	517	Missense	distal	4	no	11.334	11.135	EPSD;PhosphoSitePlus	COSMIC	10.919	Down-regulation
Other_PLK_PLK1_PLK1_ST	P30305	CDC25B	P53350	PLK1	S513	D510N	510	Missense	distal	-3	no	11.334	11.233	EPSD;PhosphoSitePlus	COSMIC	10.919	Down-regulation
Other_PLK_PLK1_PLK1_ST	P30305	CDC25B	P53350	PLK1	S513	L514F	514	Missense	proximal	1	no	11.334	12.415	EPSD;PhosphoSitePlus	COSMIC	10.919	Up-regulation
Other_PLK_PLK1_PLK1_ST	P30305	CDC25B	P53350	PLK1	S563	R562W	562	Missense	proximal	-1	no	11.189	9.898	EPSD	COSMIC	10.919	Loss
Other_PLK_PLK1_PLK1_ST	P30305	CDC25B	P53350	PLK1	S563	T556I	556	Missense	distal	-7	no	11.189	10.735	EPSD	COSMIC	10.919	Loss
Other_PLK_PLK1_PLK1_ST	P30305	CDC25B	P53350	PLK1	S563	R568Q	568	Missense	distal	5	no	11.189	10.393	EPSD	COSMIC	10.919	Loss
Other_PLK_PLK1_PLK1_ST	P30305	CDC25B	P53350	PLK1	S563	R570W	570	Missense	distal	7	no	11.189	11.207	EPSD	COSMIC	10.919	Up-regulation
Other_PLK_PLK1_PLK1_ST	P30305	CDC25B	P53350	PLK1	S563	R558H	558	Missense	distal	-5	no	11.189	10.386	EPSD	COSMIC	10.919	Loss
Other_PLK_PLK1_PLK1_ST	P30305	CDC25B	P53350	PLK1	S563	K560R	560	Missense	distal	-3	no	11.189	11.649	EPSD	COSMIC	10.919	Up-regulation
Other_PLK_PLK1_PLK1_ST	P30305	CDC25B	P53350	PLK1	S563	R570L	570	Missense	distal	7	no	11.189	11.171	EPSD	COSMIC	10.919	Down-regulation
Other_PLK_PLK1_PLK1_ST	P33981	TTK	P53350	PLK1	S49	N48S	48	Missense	proximal	-1	no	11.653	11.793	EPSD	COSMIC	10.919	Up-regulation
Other_PLK_PLK1_PLK1_ST	P33981	TTK	P53350	PLK1	S49	T46A	46	Missense	distal	-3	no	11.653	11.798	EPSD	COSMIC	10.919	Up-regulation
Other_PLK_PLK1_PLK1_ST	P33981	TTK	P53350	PLK1	S291	D289Y	289	Missense	proximal	-2	no	14.312	12.770	EPSD;PhosphoSitePlus	COSMIC	10.919	Down-regulation
Other_PLK_PLK1_PLK1_ST	P33981	TTK	P53350	PLK1	S363	E361K	361	Missense	proximal	-2	no	14.324	11.447	EPSD;PhosphoSitePlus	COSMIC	10.919	Down-regulation
Other_PLK_PLK1_PLK1_ST	P33981	TTK	P53350	PLK1	S464	C465F	465	Missense	proximal	1	no	10.301	13.114	EPSD	COSMIC	10.919	Gain
Other_PLK_PLK1_PLK1_ST	P33981	TTK	P53350	PLK1	T594	R587Q	587	Missense	distal	-7	no	10.561	10.961	EPSD;PhosphoSitePlus	COSMIC	10.919	Gain
Other_PLK_PLK1_PLK1_ST	P33981	TTK	P53350	PLK1	S742	Q735H	735	Missense	distal	-7	no	12.461	12.441	EPSD	COSMIC	10.919	Down-regulation
Other_PLK_PLK1_PLK1_ST	P33981	TTK	P53350	PLK1	S742	I737T	737	Missense	distal	-5	no	12.461	12.308	EPSD	COSMIC	10.919	Down-regulation
Other_PLK_PLK1_PLK1_ST	P33981	TTK	P53350	PLK1	S742	D749Y	749	Missense	distal	7	no	12.461	12.543	EPSD	COSMIC	10.919	Up-regulation
Other_PLK_PLK1_PLK1_ST	P33981	TTK	P53350	PLK1	S742	I737V	737	Missense	distal	-5	no	12.461	12.304	EPSD	COSMIC	10.919	Down-regulation
Other_PLK_PLK1_PLK1_ST	P33981	TTK	P53350	PLK1	T831	A828V	828	Missense	distal	-3	no	12.235	11.836	EPSD	COSMIC	10.919	Down-regulation
Other_PLK_PLK1_PLK1_ST	P33981	TTK	P53350	PLK1	S845	K848R	848	Missense	distal	3	no	13.316	13.218	EPSD	COSMIC	10.919	Down-regulation
Other_PLK_PLK1_PLK1_ST	P33981	TTK	P53350	PLK1	S845	N843I	843	Missense	proximal	-2	no	13.316	11.342	EPSD	COSMIC	10.919	Down-regulation
Other_PLK_PLK1_PLK1_ST	P33981	TTK	P53350	PLK1	S845	K852Q	852	Missense	distal	7	no	13.316	13.296	EPSD	COSMIC	10.919	Down-regulation
Other_PLK_PLK1_PLK1_ST	Q96BK5	PINX1	P53350	PLK1	S110	S110Y	110	Missense	central	0	yes	12.373	0.000	EPSD;PhosphoSitePlus	COSMIC	10.919	Loss
Other_PLK_PLK1_PLK1_ST	Q96BK5	PINX1	P53350	PLK1	S110	E114K	114	Missense	distal	4	no	12.373	12.000	EPSD;PhosphoSitePlus	COSMIC	10.919	Down-regulation
Other_PLK_PLK1_PLK1_ST	Q96BK5	PINX1	P53350	PLK1	S110	K108N	108	Missense	proximal	-2	no	12.373	14.402	EPSD;PhosphoSitePlus	COSMIC;CCLE	10.919	Up-regulation
Other_PLK_PLK1_PLK1_ST	Q96BK5	PINX1	P53350	PLK1	S110	S112G	112	Missense	proximal	2	no	12.373	10.793	EPSD;PhosphoSitePlus	COSMIC	10.919	Loss
Other_PLK_PLK1_PLK1_ST	Q96BK5	PINX1	P53350	PLK1	S110	E114Q	114	Missense	distal	4	no	12.373	11.970	EPSD;PhosphoSitePlus	COSMIC;CCLE	10.919	Down-regulation
Other_PLK_PLK1_PLK1_ST	Q96BK5	PINX1	P53350	PLK1	S117	R123S	123	Missense	distal	6	no	12.300	12.607	EPSD;PhosphoSitePlus	COSMIC	10.919	Up-regulation
Other_PLK_PLK1_PLK1_ST	Q96BK5	PINX1	P53350	PLK1	S117	S110Y	110	Missense	distal	-7	no	12.300	11.687	EPSD;PhosphoSitePlus	COSMIC	10.919	Down-regulation
Other_PLK_PLK1_PLK1_ST	Q96BK5	PINX1	P53350	PLK1	S117	E114K	114	Missense	distal	-3	no	12.300	12.840	EPSD;PhosphoSitePlus	COSMIC	10.919	Up-regulation
Other_PLK_PLK1_PLK1_ST	Q96BK5	PINX1	P53350	PLK1	S117	S120F	120	Missense	distal	3	no	12.300	12.359	EPSD;PhosphoSitePlus	COSMIC	10.919	Up-regulation
Other_PLK_PLK1_PLK1_ST	Q96BK5	PINX1	P53350	PLK1	S117	S112G	112	Missense	distal	-5	no	12.300	12.698	EPSD;PhosphoSitePlus	COSMIC	10.919	Up-regulation
Other_PLK_PLK1_PLK1_ST	Q96BK5	PINX1	P53350	PLK1	S117	E114Q	114	Missense	distal	-3	no	12.300	12.626	EPSD;PhosphoSitePlus	COSMIC;CCLE	10.919	Up-regulation
Other_PLK_PLK1_PLK1_ST	Q96BK5	PINX1	P53350	PLK1	S117	R123H	123	Missense	distal	6	no	12.300	12.084	EPSD;PhosphoSitePlus	COSMIC	10.919	Down-regulation
Other_PLK_PLK1_PLK1_ST	Q96BK5	PINX1	P53350	PLK1	S161	D159N	159	Missense	proximal	-2	no	14.209	12.966	EPSD	COSMIC	10.919	Down-regulation
Other_PLK_PLK1_PLK1_ST	Q96BK5	PINX1	P53350	PLK1	S161	S161R	161	Missense	central	0	yes	14.209	0.000	EPSD	COSMIC	10.919	Loss
Other_PLK_PLK1_PLK1_ST	Q96BK5	PINX1	P53350	PLK1	S161	P165S	165	Missense	distal	4	no	14.209	14.530	EPSD	COSMIC	10.919	Up-regulation
Other_PLK_PLK1_PLK1_ST	Q96BK5	PINX1	P53350	PLK1	S161	P162L	162	Missense	proximal	1	no	14.209	15.055	EPSD	COSMIC	10.919	Up-regulation
Other_PLK_PLK1_PLK1_ST	Q96BK5	PINX1	P53350	PLK1	T177	A183V	183	Missense	distal	6	no	11.825	11.650	EPSD	COSMIC	10.919	Down-regulation
Other_PLK_PLK1_PLK1_ST	Q96BK5	PINX1	P53350	PLK1	T177	Q179K	179	Missense	proximal	2	no	11.825	11.467	EPSD	COSMIC	10.919	Down-regulation
Other_PLK_PLK1_PLK1_ST	Q96BK5	PINX1	P53350	PLK1	T177	T170N	170	Missense	distal	-7	no	11.825	11.624	EPSD	COSMIC	10.919	Down-regulation
Other_PLK_PLK1_PLK1_ST	Q96BK5	PINX1	P53350	PLK1	T177	A175T	175	Missense	proximal	-2	no	11.825	11.206	EPSD	COSMIC;CCLE	10.919	Down-regulation
Other_PLK_PLK1_PLK1_ST	Q96BK5	PINX1	P53350	PLK1	T177	K184T	184	Missense	distal	7	no	11.825	11.759	EPSD	COSMIC	10.919	Down-regulation
Other_PLK_PLK1_PLK1_ST	Q9H1A4	ANAPC1	P53350	PLK1	S212	P208S	208	Missense	distal	-4	no	11.649	11.771	EPSD	COSMIC	10.919	Up-regulation
Other_PLK_PLK1_PLK1_ST	Q9H1A4	ANAPC1	P53350	PLK1	S212	E219G	219	Missense	distal	7	no	11.649	11.670	EPSD	COSMIC	10.919	Up-regulation
Other_PLK_PLK1_PLK1_ST	Q9H1A4	ANAPC1	P53350	PLK1	S212	E205Q	205	Missense	distal	-7	no	11.649	11.613	EPSD	COSMIC	10.919	Down-regulation
Other_PLK_PLK1_PLK1_ST	Q9H1A4	ANAPC1	P53350	PLK1	S313	P318L	318	Missense	distal	5	no	11.152	10.419	EPSD	COSMIC	10.919	Loss
Other_PLK_PLK1_PLK1_ST	Q9H1A4	ANAPC1	P53350	PLK1	S323	P318L	318	Missense	distal	-5	no	12.107	12.508	EPSD	COSMIC	10.919	Up-regulation
Other_PLK_PLK1_PLK1_ST	Q9H1A4	ANAPC1	P53350	PLK1	S343	M347T	347	Missense	distal	4	no	10.740	11.497	EPSD	COSMIC	10.919	Gain
Other_PLK_PLK1_PLK1_ST	Q9H1A4	ANAPC1	P53350	PLK1	S343	I344F	344	Missense	proximal	1	no	10.740	12.029	EPSD	COSMIC	10.919	Gain
Other_PLK_PLK1_PLK1_ST	Q9H1A4	ANAPC1	P53350	PLK1	S355	S362A	362	Missense	distal	7	no	12.258	12.283	EPSD;PhosphoSitePlus	COSMIC	10.919	Up-regulation
Other_PLK_PLK1_PLK1_ST	Q9H1A4	ANAPC1	P53350	PLK1	S377	I371S	371	Missense	distal	-6	no	13.023	12.954	EPSD;PhosphoSitePlus	COSMIC	10.919	Down-regulation
Other_PLK_PLK1_PLK1_ST	Q9H1A4	ANAPC1	P53350	PLK1	T520	P517L	517	Missense	distal	-3	no	10.514	11.706	PhosphoSitePlus;EPSD	COSMIC	10.919	Gain
Other_PLK_PLK1_PLK1_ST	Q9H1A4	ANAPC1	P53350	PLK1	T524	P517L	517	Missense	distal	-7	no	11.557	11.463	EPSD	COSMIC	10.919	Down-regulation
Other_PLK_PLK1_PLK1_ST	Q9H1A4	ANAPC1	P53350	PLK1	T530	T537A	537	Missense	distal	7	no	12.042	12.082	EPSD;PhosphoSitePlus	COSMIC;GDSC	10.919	Up-regulation
Other_PLK_PLK1_PLK1_ST	Q9H1A4	ANAPC1	P53350	PLK1	S547	K543T	543	Missense	distal	-4	no	10.928	10.958	EPSD;PhosphoSitePlus	COSMIC	10.919	Up-regulation
Other_PLK_PLK1_PLK1_ST	Q9H1A4	ANAPC1	P53350	PLK1	S547	D549H	549	Missense	proximal	2	no	10.928	10.904	EPSD;PhosphoSitePlus	COSMIC	10.919	Loss
Other_PLK_PLK1_PLK1_ST	Q9H1A4	ANAPC1	P53350	PLK1	S563	S564L	564	Missense	proximal	1	no	10.597	12.564	EPSD	COSMIC	10.919	Gain
Other_PLK_PLK1_PLK1_ST	Q9H1A4	ANAPC1	P53350	PLK1	S564	S564L	564	Missense	central	0	yes	12.442	0.000	EPSD	COSMIC	10.919	Loss
Other_PLK_PLK1_PLK1_ST	Q9H1A4	ANAPC1	P53350	PLK1	S569	S564L	564	Missense	distal	-5	no	10.344	11.008	EPSD	COSMIC	10.919	Gain
Other_PLK_PLK1_PLK1_ST	Q9H1A4	ANAPC1	P53350	PLK1	S886	L887S	887	Missense	proximal	1	no	13.913	11.945	EPSD	COSMIC	10.919	Down-regulation
Other_PLK_PLK1_PLK1_ST	Q9H1A4	ANAPC1	P53350	PLK1	S886	S892F	892	Missense	distal	6	no	13.913	13.337	EPSD	COSMIC	10.919	Down-regulation
Other_PLK_PLK1_PLK1_ST	Q9H1A4	ANAPC1	P53350	PLK1	S886	E885G	885	Missense	proximal	-1	no	13.913	12.119	EPSD	COSMIC	10.919	Down-regulation
Other_PLK_PLK1_PLK1_ST	Q9H1A4	ANAPC1	P53350	PLK1	S886	L879V	879	Missense	distal	-7	no	13.913	13.921	EPSD	COSMIC;GDSC;CCLE	10.919	Up-regulation
Other_PLK_PLK1_PLK1_ST	Q9H1A4	ANAPC1	P53350	PLK1	S892	L887S	887	Missense	distal	-5	no	12.506	11.842	EPSD	COSMIC	10.919	Down-regulation
Other_PLK_PLK1_PLK1_ST	Q9H1A4	ANAPC1	P53350	PLK1	S892	S892F	892	Missense	central	0	yes	12.506	0.000	EPSD	COSMIC	10.919	Loss
Other_PLK_PLK1_PLK1_ST	Q9H1A4	ANAPC1	P53350	PLK1	S892	E885G	885	Missense	distal	-7	no	12.506	11.871	EPSD	COSMIC	10.919	Down-regulation
Other_PLK_PLK1_PLK1_ST	Q9H1A4	ANAPC1	P53350	PLK1	S893	L887S	887	Missense	distal	-6	no	11.126	11.460	EPSD	COSMIC	10.919	Up-regulation
Other_PLK_PLK1_PLK1_ST	Q9H1A4	ANAPC1	P53350	PLK1	S893	S892F	892	Missense	proximal	-1	no	11.126	10.587	EPSD	COSMIC	10.919	Loss
Other_PLK_PLK1_PLK1_ST	Q9H1A4	ANAPC1	P53350	PLK1	S1058	S1058R	1058	Missense	central	0	yes	11.200	0.000	EPSD	COSMIC	10.919	Loss
Other_PLK_PLK1_PLK1_ST	Q9H1A4	ANAPC1	P53350	PLK1	S1773	F1771I	1771	Missense	proximal	-2	no	10.302	11.295	EPSD	COSMIC	10.919	Gain
Other_PLK_PLK1_PLK1_ST	Q99661	KIF2C	P53350	PLK1	T33	K38Q	38	Missense	distal	5	no	10.995	10.825	EPSD	COSMIC	10.919	Loss
Other_PLK_PLK1_PLK1_ST	Q99661	KIF2C	P53350	PLK1	S519	A514T	514	Missense	distal	-5	no	12.443	12.374	EPSD	COSMIC	10.919	Down-regulation
Other_PLK_PLK1_PLK1_ST	Q99661	KIF2C	P53350	PLK1	S519	L520F	520	Missense	proximal	1	no	12.443	13.523	EPSD	COSMIC	10.919	Up-regulation
Other_PLK_PLK1_PLK1_ST	Q99661	KIF2C	P53350	PLK1	S519	C526Y	526	Missense	distal	7	no	12.443	12.430	EPSD	COSMIC	10.919	Down-regulation
Other_PLK_PLK1_PLK1_ST	Q99661	KIF2C	P53350	PLK1	S551	F552S	552	Missense	proximal	1	no	14.177	11.128	EPSD	COSMIC;CCLE	10.919	Down-regulation
Other_PLK_PLK1_PLK1_ST	Q99661	KIF2C	P53350	PLK1	S589	P594T	594	Missense	distal	5	no	14.763	13.771	EPSD	COSMIC	10.919	Down-regulation
Other_PLK_PLK1_PLK1_ST	Q99661	KIF2C	P53350	PLK1	S589	P590H	590	Missense	proximal	1	no	14.763	13.874	EPSD	COSMIC	10.919	Down-regulation
Other_PLK_PLK1_PLK1_ST	Q99661	KIF2C	P53350	PLK1	S589	L588M	588	Missense	proximal	-1	no	14.763	15.294	EPSD	COSMIC;GDSC;CCLE	10.919	Up-regulation
Other_PLK_PLK1_PLK1_ST	Q99661	KIF2C	P53350	PLK1	S621	E623G	623	Missense	proximal	2	no	11.674	10.685	EPSD;PhosphoSitePlus	COSMIC	10.919	Loss
Other_PLK_PLK1_PLK1_ST	Q99661	KIF2C	P53350	PLK1	S621	E623D	623	Missense	proximal	2	no	11.674	12.265	EPSD;PhosphoSitePlus	COSMIC	10.919	Up-regulation
Other_PLK_PLK1_PLK1_ST	Q99661	KIF2C	P53350	PLK1	S633	M631K	631	Missense	proximal	-2	no	13.762	13.599	PhosphoSitePlus;EPSD	COSMIC;GDSC;CCLE	10.919	Down-regulation
Other_PLK_PLK1_PLK1_ST	Q99661	KIF2C	P53350	PLK1	S633	M638I	638	Missense	distal	5	no	13.762	13.963	PhosphoSitePlus;EPSD	COSMIC	10.919	Up-regulation
Other_PLK_PLK1_PLK1_ST	Q99661	KIF2C	P53350	PLK1	S633	A637V	637	Missense	distal	4	no	13.762	13.499	PhosphoSitePlus;EPSD	COSMIC	10.919	Down-regulation
Other_PLK_PLK1_PLK1_ST	Q99661	KIF2C	P53350	PLK1	T639	M638I	638	Missense	proximal	-1	no	11.385	11.330	EPSD	COSMIC	10.919	Down-regulation
Other_PLK_PLK1_PLK1_ST	Q99661	KIF2C	P53350	PLK1	T639	A637V	637	Missense	proximal	-2	no	11.385	11.344	EPSD	COSMIC	10.919	Down-regulation
Other_PLK_PLK1_PLK1_ST	P35568	IRS1	P53350	PLK1	S99	E100K	100	Missense	proximal	1	no	11.482	11.031	EPSD	COSMIC	10.919	Down-regulation
Other_PLK_PLK1_PLK1_ST	P35568	IRS1	P53350	PLK1	S99	E100Q	100	Missense	proximal	1	no	11.482	11.605	EPSD	COSMIC	10.919	Up-regulation
Other_PLK_PLK1_PLK1_ST	P35568	IRS1	P53350	PLK1	S193	K190N	190	Missense	distal	-3	no	11.581	11.399	EPSD	COSMIC	10.919	Down-regulation
Other_PLK_PLK1_PLK1_ST	P35568	IRS1	P53350	PLK1	S193	S189N	189	Missense	distal	-4	no	11.581	11.446	EPSD	COSMIC	10.919	Down-regulation
Other_PLK_PLK1_PLK1_ST	P35568	IRS1	P53350	PLK1	S307	I308M	308	Missense	proximal	1	no	10.342	11.307	EPSD	COSMIC	10.919	Gain
Other_PLK_PLK1_PLK1_ST	P35568	IRS1	P53350	PLK1	T309	A310V	310	Missense	proximal	1	no	10.031	11.469	EPSD	COSMIC	10.919	Gain
Other_PLK_PLK1_PLK1_ST	P35568	IRS1	P53350	PLK1	S312	P313L	313	Missense	proximal	1	no	10.433	11.279	EPSD	COSMIC;GDSC;CCLE	10.919	Gain
Other_PLK_PLK1_PLK1_ST	P35568	IRS1	P53350	PLK1	S312	M316V	316	Missense	distal	4	no	10.433	10.920	EPSD	COSMIC	10.919	Gain
Other_PLK_PLK1_PLK1_ST	P35568	IRS1	P53350	PLK1	S330	G332R	332	Missense	proximal	2	no	10.743	11.595	EPSD	COSMIC	10.919	Gain
Other_PLK_PLK1_PLK1_ST	P35568	IRS1	P53350	PLK1	S330	F324L	324	Missense	distal	-6	no	10.743	10.926	EPSD	COSMIC	10.919	Gain
Other_PLK_PLK1_PLK1_ST	P35568	IRS1	P53350	PLK1	T335	G332R	332	Missense	distal	-3	no	10.868	10.927	EPSD	COSMIC	10.919	Gain
Other_PLK_PLK1_PLK1_ST	P35568	IRS1	P53350	PLK1	S345	S341L	341	Missense	distal	-4	no	12.466	12.273	EPSD	COSMIC	10.919	Down-regulation
Other_PLK_PLK1_PLK1_ST	P35568	IRS1	P53350	PLK1	S345	N352D	352	Missense	distal	7	no	12.466	12.384	EPSD	COSMIC	10.919	Down-regulation
Other_PLK_PLK1_PLK1_ST	P35568	IRS1	P53350	PLK1	S345	P349L	349	Missense	distal	4	no	12.466	12.176	EPSD	COSMIC	10.919	Down-regulation
Other_PLK_PLK1_PLK1_ST	P35568	IRS1	P53350	PLK1	S345	P346S	346	Missense	proximal	1	no	12.466	11.345	EPSD	COSMIC	10.919	Down-regulation
Other_PLK_PLK1_PLK1_ST	P35568	IRS1	P53350	PLK1	S372	L369F	369	Missense	distal	-3	no	14.136	12.732	EPSD	COSMIC	10.919	Down-regulation
Other_PLK_PLK1_PLK1_ST	P35568	IRS1	P53350	PLK1	S372	A379P	379	Missense	distal	7	no	14.136	14.138	EPSD	COSMIC	10.919	Up-regulation
Other_PLK_PLK1_PLK1_ST	P35568	IRS1	P53350	PLK1	S398	S398G	398	Missense	central	0	yes	11.301	0.000	EPSD	COSMIC	10.919	Loss
Other_PLK_PLK1_PLK1_ST	P35568	IRS1	P53350	PLK1	S398	G401D	401	Missense	distal	3	no	11.301	11.543	EPSD	COSMIC	10.919	Up-regulation
Other_PLK_PLK1_PLK1_ST	P35568	IRS1	P53350	PLK1	S398	T403S	403	Missense	distal	5	no	11.301	11.906	EPSD	COSMIC	10.919	Up-regulation
Other_PLK_PLK1_PLK1_ST	P35568	IRS1	P53350	PLK1	S398	H400Q	400	Missense	proximal	2	no	11.301	10.923	EPSD	COSMIC	10.919	Down-regulation
Other_PLK_PLK1_PLK1_ST	P35568	IRS1	P53350	PLK1	S398	S395I	395	Missense	distal	-3	no	11.301	11.700	EPSD	COSMIC;GDSC;CCLE	10.919	Up-regulation
Other_PLK_PLK1_PLK1_ST	P35568	IRS1	P53350	PLK1	S415	S415L	415	Missense	central	0	yes	11.677	0.000	EPSD	COSMIC	10.919	Loss
Other_PLK_PLK1_PLK1_ST	P35568	IRS1	P53350	PLK1	S415	G418V	418	Missense	distal	3	no	11.677	11.826	EPSD	COSMIC;GDSC;CCLE	10.919	Up-regulation
Other_PLK_PLK1_PLK1_ST	P35568	IRS1	P53350	PLK1	S415	D422N	422	Missense	distal	7	no	11.677	11.759	EPSD	COSMIC	10.919	Up-regulation
Other_PLK_PLK1_PLK1_ST	P35568	IRS1	P53350	PLK1	S434	P435F	435	Missense	proximal	1	no	9.577	11.504	EPSD	COSMIC	10.919	Gain
Other_PLK_PLK1_PLK1_ST	P35568	IRS1	P53350	PLK1	S449	G451C	451	Missense	proximal	2	no	11.095	11.703	EPSD	COSMIC	10.919	Up-regulation
Other_PLK_PLK1_PLK1_ST	P35568	IRS1	P53350	PLK1	S449	D448E	448	Missense	proximal	-1	no	11.095	10.298	EPSD	COSMIC	10.919	Loss
Other_PLK_PLK1_PLK1_ST	P35568	IRS1	P53350	PLK1	S449	T453I	453	Missense	distal	4	no	11.095	10.096	EPSD	COSMIC	10.919	Loss
Other_PLK_PLK1_PLK1_ST	P35568	IRS1	P53350	PLK1	S449	R443C	443	Missense	distal	-6	no	11.095	10.339	EPSD	COSMIC	10.919	Loss
Other_PLK_PLK1_PLK1_ST	P35568	IRS1	P53350	PLK1	S449	P447L	447	Missense	proximal	-2	no	11.095	10.731	EPSD	COSMIC	10.919	Loss
Other_PLK_PLK1_PLK1_ST	P35568	IRS1	P53350	PLK1	S449	R443L	443	Missense	distal	-6	no	11.095	11.208	EPSD	COSMIC	10.919	Up-regulation
Other_PLK_PLK1_PLK1_ST	P35568	IRS1	P53350	PLK1	S449	S444I	444	Missense	distal	-5	no	11.095	11.463	EPSD	COSMIC	10.919	Up-regulation
Other_PLK_PLK1_PLK1_ST	P35568	IRS1	P53350	PLK1	S449	S449P	449	Missense	central	0	yes	11.095	0.000	EPSD	COSMIC	10.919	Loss
Other_PLK_PLK1_PLK1_ST	P35568	IRS1	P53350	PLK1	S463	E460K	460	Missense	distal	-3	no	10.684	11.224	EPSD	COSMIC	10.919	Gain
Other_PLK_PLK1_PLK1_ST	P35568	IRS1	P53350	PLK1	S527	G529D	529	Missense	proximal	2	no	10.106	11.685	EPSD	COSMIC	10.919	Gain
Other_PLK_PLK1_PLK1_ST	P35568	IRS1	P53350	PLK1	S531	T533I	533	Missense	proximal	2	no	10.083	11.145	EPSD	COSMIC	10.919	Gain
Other_PLK_PLK1_PLK1_ST	P35568	IRS1	P53350	PLK1	S531	G529D	529	Missense	proximal	-2	no	10.083	13.405	EPSD	COSMIC	10.919	Gain
Other_PLK_PLK1_PLK1_ST	P35568	IRS1	P53350	PLK1	T552	M554T	554	Missense	proximal	2	no	11.154	10.516	EPSD	COSMIC	10.919	Loss
Other_PLK_PLK1_PLK1_ST	P35568	IRS1	P53350	PLK1	T552	Y558C	558	Missense	distal	6	no	11.154	10.749	EPSD	COSMIC	10.919	Loss
Other_PLK_PLK1_PLK1_ST	P35568	IRS1	P53350	PLK1	T552	Y551C	551	Missense	proximal	-1	no	11.154	8.958	EPSD	COSMIC	10.919	Loss
Other_PLK_PLK1_PLK1_ST	P35568	IRS1	P53350	PLK1	S603	H598R	598	Missense	distal	-5	no	10.116	10.919	EPSD	COSMIC	10.919	Gain
Other_PLK_PLK1_PLK1_ST	P35568	IRS1	P53350	PLK1	T605	H598R	598	Missense	distal	-7	no	11.317	10.938	EPSD	COSMIC	10.919	Down-regulation
Other_PLK_PLK1_PLK1_ST	P35568	IRS1	P53350	PLK1	T605	H599Y	599	Missense	distal	-6	no	11.317	10.453	EPSD	COSMIC	10.919	Loss
Other_PLK_PLK1_PLK1_ST	P35568	IRS1	P53350	PLK1	T605	H599Q	599	Missense	distal	-6	no	11.317	11.306	EPSD	COSMIC	10.919	Down-regulation
Other_PLK_PLK1_PLK1_ST	P35568	IRS1	P53350	PLK1	S741	V738G	738	Missense	distal	-3	no	11.207	11.855	EPSD	COSMIC	10.919	Up-regulation
Other_PLK_PLK1_PLK1_ST	P35568	IRS1	P53350	PLK1	S741	G739E	739	Missense	proximal	-2	no	11.207	14.135	EPSD	COSMIC	10.919	Up-regulation
Other_PLK_PLK1_PLK1_ST	P35568	IRS1	P53350	PLK1	S741	N734I	734	Missense	distal	-7	no	11.207	10.954	EPSD	COSMIC	10.919	Down-regulation
Other_PLK_PLK1_PLK1_ST	P35568	IRS1	P53350	PLK1	S741	N734K	734	Missense	distal	-7	no	11.207	11.051	EPSD	COSMIC	10.919	Down-regulation
Other_PLK_PLK1_PLK1_ST	P35568	IRS1	P53350	PLK1	S862	G864W	864	Missense	proximal	2	no	10.269	11.868	EPSD	COSMIC	10.919	Gain
Other_PLK_PLK1_PLK1_ST	P35568	IRS1	P53350	PLK1	S1038	A1042T	1042	Missense	distal	4	no	10.994	11.000	EPSD	COSMIC	10.919	Up-regulation
Other_PLK_PLK1_PLK1_ST	P35568	IRS1	P53350	PLK1	S1038	S1043F	1043	Missense	distal	5	no	10.994	11.088	EPSD	COSMIC	10.919	Up-regulation
Other_PLK_PLK1_PLK1_ST	P35568	IRS1	P53350	PLK1	S1078	P1079S	1079	Missense	proximal	1	no	11.775	10.653	EPSD	COSMIC	10.919	Loss
Other_PLK_PLK1_PLK1_ST	P35568	IRS1	P53350	PLK1	S1078	S1078I	1078	Missense	central	0	yes	11.775	0.000	EPSD	COSMIC	10.919	Loss
Other_PLK_PLK1_PLK1_ST	P35568	IRS1	P53350	PLK1	S1078	R1074L	1074	Missense	distal	-4	no	11.775	12.148	EPSD	COSMIC;CCLE	10.919	Up-regulation
Other_PLK_PLK1_PLK1_ST	P35568	IRS1	P53350	PLK1	S1078	R1074Q	1074	Missense	distal	-4	no	11.775	12.063	EPSD	COSMIC;GDSC	10.919	Up-regulation
Other_PLK_PLK1_PLK1_ST	P35568	IRS1	P53350	PLK1	S1078	R1081C	1081	Missense	distal	3	no	11.775	11.834	EPSD	COSMIC	10.919	Up-regulation
Other_PLK_PLK1_PLK1_ST	P35568	IRS1	P53350	PLK1	S1132	G1128S	1128	Missense	distal	-4	no	11.149	11.803	EPSD	COSMIC	10.919	Up-regulation
Other_PLK_PLK1_PLK1_ST	P35568	IRS1	P53350	PLK1	S1132	G1130S	1130	Missense	proximal	-2	no	11.149	11.819	EPSD	COSMIC	10.919	Up-regulation
Other_PLK_PLK1_PLK1_ST	P35568	IRS1	P53350	PLK1	S1227	R1220C	1220	Missense	distal	-7	no	11.646	11.526	EPSD	COSMIC	10.919	Down-regulation
Other_PLK_PLK1_PLK1_ST	P35568	IRS1	P53350	PLK1	S1227	D1225Y	1225	Missense	proximal	-2	no	11.646	10.104	EPSD	COSMIC	10.919	Loss
Other_PLK_PLK1_PLK1_ST	P35568	IRS1	P53350	PLK1	S1227	A1228V	1228	Missense	proximal	1	no	11.646	13.084	EPSD	COSMIC	10.919	Up-regulation
Other_PLK_PLK1_PLK1_ST	P35568	IRS1	P53350	PLK1	S1227	E1224Q	1224	Missense	distal	-3	no	11.646	11.972	EPSD	COSMIC	10.919	Up-regulation
Other_PLK_PLK1_PLK1_ST	P35568	IRS1	P53350	PLK1	S1227	L1226V	1226	Missense	proximal	-1	no	11.646	11.149	EPSD	COSMIC	10.919	Down-regulation
Other_PLK_PLK1_PLK1_ST	P35568	IRS1	P53350	PLK1	S1231	D1225Y	1225	Missense	distal	-6	no	14.335	13.565	EPSD	COSMIC	10.919	Down-regulation
Other_PLK_PLK1_PLK1_ST	P35568	IRS1	P53350	PLK1	S1231	Q1235P	1235	Missense	distal	4	no	14.335	14.428	EPSD	COSMIC	10.919	Up-regulation
Other_PLK_PLK1_PLK1_ST	P35568	IRS1	P53350	PLK1	S1231	A1228V	1228	Missense	distal	-3	no	14.335	13.936	EPSD	COSMIC	10.919	Down-regulation
Other_PLK_PLK1_PLK1_ST	P35568	IRS1	P53350	PLK1	S1231	E1224Q	1224	Missense	distal	-7	no	14.335	14.299	EPSD	COSMIC	10.919	Down-regulation
Other_PLK_PLK1_PLK1_ST	P35568	IRS1	P53350	PLK1	S1231	L1226V	1226	Missense	distal	-5	no	14.335	13.882	EPSD	COSMIC	10.919	Down-regulation
Other_PLK_PLK1_PLK1_ST	Q49MG5	MAP9	P53350	PLK1	S165	D170E	170	Missense	distal	5	no	11.318	10.877	EPSD	COSMIC	10.919	Loss
Other_PLK_PLK1_PLK1_ST	Q49MG5	MAP9	P53350	PLK1	S165	N163S	163	Missense	proximal	-2	no	11.318	9.908	EPSD	COSMIC;CCLE	10.919	Loss
Other_PLK_PLK1_PLK1_ST	Q49MG5	MAP9	P53350	PLK1	S238	N232S	232	Missense	distal	-6	no	12.706	12.902	EPSD	COSMIC	10.919	Up-regulation
Other_PLK_PLK1_PLK1_ST	Q49MG5	MAP9	P53350	PLK1	S255	S257T	257	Missense	proximal	2	no	11.924	11.284	EPSD	COSMIC	10.919	Down-regulation
Other_PLK_PLK1_PLK1_ST	Q49MG5	MAP9	P53350	PLK1	S255	G262E	262	Missense	distal	7	no	11.924	11.903	EPSD	COSMIC	10.919	Down-regulation
Other_PLK_PLK1_PLK1_ST	Q49MG5	MAP9	P53350	PLK1	S289	V295E	295	Missense	distal	6	no	13.258	13.272	PhosphoSitePlus	COSMIC	10.919	Up-regulation
Other_PLK_PLK1_PLK1_ST	Q49MG5	MAP9	P53350	PLK1	S336	S336C	336	Missense	central	0	yes	11.933	0.000	EPSD	COSMIC	10.919	Loss
Other_PLK_PLK1_PLK1_ST	Q49MG5	MAP9	P53350	PLK1	S336	K335N	335	Missense	proximal	-1	no	11.933	12.367	EPSD	COSMIC	10.919	Up-regulation
Other_PLK_PLK1_PLK1_ST	Q49MG5	MAP9	P53350	PLK1	S336	K335E	335	Missense	proximal	-1	no	11.933	12.504	EPSD	COSMIC	10.919	Up-regulation
Other_PLK_PLK1_PLK1_ST	Q49MG5	MAP9	P53350	PLK1	T364	K359E	359	Missense	distal	-5	no	11.677	11.434	EPSD	COSMIC	10.919	Down-regulation
Other_PLK_PLK1_PLK1_ST	Q49MG5	MAP9	P53350	PLK1	S625	S625C	625	Missense	central	0	yes	12.527	0.000	EPSD	COSMIC	10.919	Loss
Other_PLK_PLK1_PLK1_ST	Q49MG5	MAP9	P53350	PLK1	S625	R623H	623	Missense	proximal	-2	no	12.527	12.218	EPSD	COSMIC	10.919	Down-regulation
Other_PLK_PLK1_PLK1_ST	Q49MG5	MAP9	P53350	PLK1	S625	K621E	621	Missense	distal	-4	no	12.527	12.910	EPSD	COSMIC	10.919	Up-regulation
Other_PLK_PLK1_PLK1_ST	O95613	PCNT	P53350	PLK1	S49	P55L	55	Missense	distal	6	no	13.249	13.145	EPSD	COSMIC	10.919	Down-regulation
Other_PLK_PLK1_PLK1_ST	O95613	PCNT	P53350	PLK1	S49	A48P	48	Missense	proximal	-1	no	13.249	12.542	EPSD	COSMIC	10.919	Down-regulation
Other_PLK_PLK1_PLK1_ST	O95613	PCNT	P53350	PLK1	S49	S49F	49	Missense	central	0	yes	13.249	0.000	EPSD	COSMIC	10.919	Loss
Other_PLK_PLK1_PLK1_ST	O95613	PCNT	P53350	PLK1	S54	P55L	55	Missense	proximal	1	no	11.950	12.796	EPSD	COSMIC	10.919	Up-regulation
Other_PLK_PLK1_PLK1_ST	O95613	PCNT	P53350	PLK1	S54	A48P	48	Missense	distal	-6	no	11.950	11.362	EPSD	COSMIC	10.919	Down-regulation
Other_PLK_PLK1_PLK1_ST	O95613	PCNT	P53350	PLK1	S54	S49F	49	Missense	distal	-5	no	11.950	11.689	EPSD	COSMIC	10.919	Down-regulation
Other_PLK_PLK1_PLK1_ST	O95613	PCNT	P53350	PLK1	S54	T57P	57	Missense	distal	3	no	11.950	12.109	EPSD	COSMIC	10.919	Up-regulation
Other_PLK_PLK1_PLK1_ST	O95613	PCNT	P53350	PLK1	S61	P55L	55	Missense	distal	-6	no	10.676	10.965	EPSD	COSMIC	10.919	Gain
Other_PLK_PLK1_PLK1_ST	O95613	PCNT	P53350	PLK1	T191	H190L	190	Missense	proximal	-1	no	11.769	11.248	EPSD	COSMIC	10.919	Down-regulation
Other_PLK_PLK1_PLK1_ST	O95613	PCNT	P53350	PLK1	T495	R497H	497	Missense	proximal	2	no	10.244	10.947	EPSD	COSMIC	10.919	Gain
Other_PLK_PLK1_PLK1_ST	O95613	PCNT	P53350	PLK1	T539	Q543H	543	Missense	distal	4	no	13.475	13.369	EPSD	COSMIC	10.919	Down-regulation
Other_PLK_PLK1_PLK1_ST	O95613	PCNT	P53350	PLK1	T829	D832N	832	Missense	distal	3	no	11.371	11.171	EPSD	COSMIC;CCLE	10.919	Down-regulation
Other_PLK_PLK1_PLK1_ST	O95613	PCNT	P53350	PLK1	T829	A833D	833	Missense	distal	4	no	11.371	11.573	EPSD	COSMIC	10.919	Up-regulation
Other_PLK_PLK1_PLK1_ST	O95613	PCNT	P53350	PLK1	S936	T931I	931	Missense	distal	-5	no	10.860	11.014	EPSD	COSMIC	10.919	Gain
Other_PLK_PLK1_PLK1_ST	O95613	PCNT	P53350	PLK1	S1006	S1006F	1006	Missense	central	0	yes	13.306	0.000	EPSD	COSMIC	10.919	Loss
Other_PLK_PLK1_PLK1_ST	O95613	PCNT	P53350	PLK1	S1006	E999K	999	Missense	distal	-7	no	13.306	13.002	EPSD	COSMIC	10.919	Down-regulation
Other_PLK_PLK1_PLK1_ST	O95613	PCNT	P53350	PLK1	S1006	D1005Y	1005	Missense	proximal	-1	no	13.306	12.850	EPSD	COSMIC;GDSC;CCLE	10.919	Down-regulation
Other_PLK_PLK1_PLK1_ST	O95613	PCNT	P53350	PLK1	S1092	K1097R	1097	Missense	distal	5	no	10.335	10.960	EPSD	COSMIC	10.919	Gain
Other_PLK_PLK1_PLK1_ST	O95613	PCNT	P53350	PLK1	T1209	P1216S	1216	Missense	distal	7	no	12.997	12.970	EPSD;PhosphoSitePlus	COSMIC	10.919	Down-regulation
Other_PLK_PLK1_PLK1_ST	O95613	PCNT	P53350	PLK1	T1209	E1208K	1208	Missense	proximal	-1	no	12.997	12.426	EPSD;PhosphoSitePlus	COSMIC	10.919	Down-regulation
Other_PLK_PLK1_PLK1_ST	O95613	PCNT	P53350	PLK1	T1209	A1205V	1205	Missense	distal	-4	no	12.997	12.857	EPSD;PhosphoSitePlus	COSMIC	10.919	Down-regulation
Other_PLK_PLK1_PLK1_ST	O95613	PCNT	P53350	PLK1	T1221	P1216S	1216	Missense	distal	-5	no	14.108	13.845	PhosphoSitePlus;EPSD	COSMIC	10.919	Down-regulation
Other_PLK_PLK1_PLK1_ST	O95613	PCNT	P53350	PLK1	T1221	D1219G	1219	Missense	proximal	-2	no	14.108	10.786	PhosphoSitePlus;EPSD	COSMIC	10.919	Loss
Other_PLK_PLK1_PLK1_ST	O95613	PCNT	P53350	PLK1	S1235	S1236N	1236	Missense	proximal	1	no	10.566	11.306	EPSD;PhosphoSitePlus	COSMIC	10.919	Gain
Other_PLK_PLK1_PLK1_ST	O95613	PCNT	P53350	PLK1	S1296	R1290H	1290	Missense	distal	-6	no	12.290	12.749	EPSD	COSMIC	10.919	Up-regulation
Other_PLK_PLK1_PLK1_ST	O95613	PCNT	P53350	PLK1	S1296	A1303E	1303	Missense	distal	7	no	12.290	12.242	EPSD	COSMIC	10.919	Down-regulation
Other_PLK_PLK1_PLK1_ST	O95613	PCNT	P53350	PLK1	S1693	S1688I	1688	Missense	distal	-5	no	11.299	11.667	EPSD	COSMIC	10.919	Up-regulation
Other_PLK_PLK1_PLK1_ST	O95613	PCNT	P53350	PLK1	T2085	R2079C	2079	Missense	distal	-6	no	13.562	12.807	EPSD	COSMIC	10.919	Down-regulation
Other_PLK_PLK1_PLK1_ST	O95613	PCNT	P53350	PLK1	T2085	S2083F	2083	Missense	proximal	-2	no	13.562	12.005	EPSD	COSMIC	10.919	Down-regulation
Other_PLK_PLK1_PLK1_ST	O95613	PCNT	P53350	PLK1	S2177	P2178L	2178	Missense	proximal	1	no	10.596	11.442	EPSD	COSMIC	10.919	Gain
Other_PLK_PLK1_PLK1_ST	O95613	PCNT	P53350	PLK1	S2183	P2178L	2178	Missense	distal	-5	no	12.264	12.665	EPSD	COSMIC	10.919	Up-regulation
Other_PLK_PLK1_PLK1_ST	O95613	PCNT	P53350	PLK1	S2189	S2191P	2191	Missense	proximal	2	no	12.182	10.706	EPSD	COSMIC	10.919	Loss
Other_PLK_PLK1_PLK1_ST	O95613	PCNT	P53350	PLK1	S2222	G2217R	2217	Missense	distal	-5	no	13.347	13.632	EPSD	COSMIC	10.919	Up-regulation
Other_PLK_PLK1_PLK1_ST	O95613	PCNT	P53350	PLK1	S2339	L2332S	2332	Missense	distal	-7	no	11.355	11.660	EPSD	COSMIC	10.919	Up-regulation
Other_PLK_PLK1_PLK1_ST	O95613	PCNT	P53350	PLK1	S2372	P2368L	2368	Missense	distal	-4	no	11.707	11.635	EPSD	COSMIC	10.919	Down-regulation
Other_PLK_PLK1_PLK1_ST	O95613	PCNT	P53350	PLK1	S2372	G2373E	2373	Missense	proximal	1	no	11.707	11.461	EPSD	COSMIC;GDSC	10.919	Down-regulation
Other_PLK_PLK1_PLK1_ST	O95613	PCNT	P53350	PLK1	T2584	E2590A	2590	Missense	distal	6	no	10.885	11.046	EPSD	COSMIC	10.919	Gain
Other_PLK_PLK1_PLK1_ST	O95613	PCNT	P53350	PLK1	T2604	L2598H	2598	Missense	distal	-6	no	11.589	11.934	EPSD	COSMIC	10.919	Up-regulation
Other_PLK_PLK1_PLK1_ST	O95613	PCNT	P53350	PLK1	T2604	E2602V	2602	Missense	proximal	-2	no	11.589	9.370	EPSD	COSMIC	10.919	Loss
Other_PLK_PLK1_PLK1_ST	O95613	PCNT	P53350	PLK1	T2604	S2611C	2611	Missense	distal	7	no	11.589	11.657	EPSD	COSMIC	10.919	Up-regulation
Other_PLK_PLK1_PLK1_ST	O95613	PCNT	P53350	PLK1	S2727	K2720E	2720	Missense	distal	-7	no	10.708	11.012	EPSD	COSMIC	10.919	Gain
Other_PLK_PLK1_PLK1_ST	O95613	PCNT	P53350	PLK1	S2860	C2859Y	2859	Missense	proximal	-1	no	11.426	13.622	EPSD	COSMIC	10.919	Up-regulation
Other_PLK_PLK1_PLK1_ST	O95613	PCNT	P53350	PLK1	S2860	E2864Q	2864	Missense	distal	4	no	11.426	11.022	EPSD	COSMIC	10.919	Down-regulation
Other_PLK_PLK1_PLK1_ST	O95613	PCNT	P53350	PLK1	T3000	T3005M	3005	Missense	distal	5	no	10.900	11.601	EPSD	COSMIC	10.919	Gain
Other_PLK_PLK1_PLK1_ST	O95613	PCNT	P53350	PLK1	T3000	T3005A	3005	Missense	distal	5	no	10.900	12.071	EPSD	COSMIC	10.919	Gain
Other_PLK_PLK1_PLK1_ST	O95613	PCNT	P53350	PLK1	S3070	L3076F	3076	Missense	distal	6	no	11.391	10.775	EPSD	COSMIC	10.919	Loss
Other_PLK_PLK1_PLK1_ST	O95613	PCNT	P53350	PLK1	S3070	S3074F	3074	Missense	distal	4	no	11.391	10.577	EPSD	COSMIC	10.919	Loss
Other_PLK_PLK1_PLK1_ST	O95613	PCNT	P53350	PLK1	S3074	L3076F	3076	Missense	proximal	2	no	11.095	10.472	EPSD	COSMIC	10.919	Loss
Other_PLK_PLK1_PLK1_ST	O95613	PCNT	P53350	PLK1	S3074	S3074F	3074	Missense	central	0	yes	11.095	0.000	EPSD	COSMIC	10.919	Loss
Other_PLK_PLK1_PLK1_ST	O95613	PCNT	P53350	PLK1	S3074	K3081E	3081	Missense	distal	7	no	11.095	11.022	EPSD	COSMIC	10.919	Down-regulation
Other_PLK_PLK1_PLK1_ST	O95613	PCNT	P53350	PLK1	S3292	R3291T	3291	Missense	proximal	-1	no	12.598	12.788	EPSD	COSMIC;CCLE	10.919	Up-regulation
Other_PLK_PLK1_PLK1_ST	O95613	PCNT	P53350	PLK1	S3296	R3291T	3291	Missense	distal	-5	no	12.449	11.980	EPSD	COSMIC;CCLE	10.919	Down-regulation
Other_PLK_PLK1_PLK1_ST	P30307	CDC25C	P53350	PLK1	S61	L54V	54	Missense	distal	-7	no	12.984	12.992	EPSD	COSMIC	10.919	Up-regulation
Other_PLK_PLK1_PLK1_ST	P30307	CDC25C	P53350	PLK1	S75	R70L	70	Missense	distal	-5	no	12.138	12.118	PhosphoSitePlus;EPSD	COSMIC	10.919	Down-regulation
Other_PLK_PLK1_PLK1_ST	P30307	CDC25C	P53350	PLK1	S168	S168F	168	Missense	central	0	yes	11.257	0.000	EPSD	COSMIC	10.919	Loss
Other_PLK_PLK1_PLK1_ST	P30307	CDC25C	P53350	PLK1	S168	S161L	161	Missense	distal	-7	no	11.257	10.953	EPSD	COSMIC	10.919	Down-regulation
Other_PLK_PLK1_PLK1_ST	P30307	CDC25C	P53350	PLK1	T268	D266H	266	Missense	proximal	-2	no	13.198	10.011	EPSD	COSMIC	10.919	Loss
Other_PLK_PLK1_PLK1_ST	P30307	CDC25C	P53350	PLK1	T268	L264R	264	Missense	distal	-4	no	13.198	12.825	EPSD	COSMIC	10.919	Down-regulation
Other_PLK_PLK1_PLK1_ST	P30307	CDC25C	P53350	PLK1	S277	D276N	276	Missense	proximal	-1	no	12.100	11.167	EPSD	COSMIC	10.919	Down-regulation
Other_PLK_PLK1_PLK1_ST	P30307	CDC25C	P53350	PLK1	S451	R448Q	448	Missense	distal	-3	no	11.295	10.620	EPSD	COSMIC	10.919	Loss
Other_PLK_PLK1_PLK1_ST	O43663	PRC1	P53350	PLK1	S11	K17N	17	Missense	distal	6	no	11.568	11.566	EPSD	COSMIC	10.919	Down-regulation
Other_PLK_PLK1_PLK1_ST	O43663	PRC1	P53350	PLK1	S11	Q16H	16	Missense	distal	5	no	11.568	11.713	EPSD	COSMIC	10.919	Up-regulation
Other_PLK_PLK1_PLK1_ST	O43663	PRC1	P53350	PLK1	S70	V71I	71	Missense	proximal	1	no	11.396	11.587	EPSD	COSMIC	10.919	Up-regulation
Other_PLK_PLK1_PLK1_ST	O43663	PRC1	P53350	PLK1	T262	G266W	266	Missense	distal	4	no	12.022	11.702	EPSD	COSMIC	10.919	Down-regulation
Other_PLK_PLK1_PLK1_ST	O43663	PRC1	P53350	PLK1	T262	A261P	261	Missense	proximal	-1	no	12.022	11.315	EPSD	COSMIC;GDSC;CCLE	10.919	Down-regulation
Other_PLK_PLK1_PLK1_ST	O43663	PRC1	P53350	PLK1	T262	I263V	263	Missense	proximal	1	no	12.022	11.831	EPSD	COSMIC	10.919	Down-regulation
Other_PLK_PLK1_PLK1_ST	O43663	PRC1	P53350	PLK1	T262	G266E	266	Missense	distal	4	no	12.022	12.096	EPSD	COSMIC	10.919	Up-regulation
Other_PLK_PLK1_PLK1_ST	O43663	PRC1	P53350	PLK1	T262	G266R	266	Missense	distal	4	no	12.022	11.163	EPSD	COSMIC	10.919	Down-regulation
Other_PLK_PLK1_PLK1_ST	O43663	PRC1	P53350	PLK1	S265	G266W	266	Missense	proximal	1	no	10.345	10.947	EPSD	COSMIC	10.919	Gain
Other_PLK_PLK1_PLK1_ST	O43663	PRC1	P53350	PLK1	S265	I263V	263	Missense	proximal	-2	no	10.345	10.949	EPSD	COSMIC	10.919	Gain
Other_PLK_PLK1_PLK1_ST	O43663	PRC1	P53350	PLK1	T491	R486H	486	Missense	distal	-5	no	11.839	11.036	EPSD	COSMIC	10.919	Down-regulation
Other_PLK_PLK1_PLK1_ST	O43663	PRC1	P53350	PLK1	S500	F506I	506	Missense	distal	6	no	11.291	11.868	EPSD	COSMIC	10.919	Up-regulation
Other_PLK_PLK1_PLK1_ST	O43663	PRC1	P53350	PLK1	S500	G507E	507	Missense	distal	7	no	11.291	11.269	EPSD	COSMIC;GDSC;CCLE	10.919	Down-regulation
Other_PLK_PLK1_PLK1_ST	O43663	PRC1	P53350	PLK1	S500	N499D	499	Missense	proximal	-1	no	11.291	12.224	EPSD	COSMIC	10.919	Up-regulation
Other_PLK_PLK1_PLK1_ST	O43663	PRC1	P53350	PLK1	S501	F506I	506	Missense	distal	5	no	11.409	11.613	EPSD	COSMIC	10.919	Up-regulation
Other_PLK_PLK1_PLK1_ST	O43663	PRC1	P53350	PLK1	S501	G507E	507	Missense	distal	6	no	11.409	11.735	EPSD	COSMIC;GDSC;CCLE	10.919	Up-regulation
Other_PLK_PLK1_PLK1_ST	O43663	PRC1	P53350	PLK1	S501	N499D	499	Missense	proximal	-2	no	11.409	12.652	EPSD	COSMIC	10.919	Up-regulation
Other_PLK_PLK1_PLK1_ST	O43663	PRC1	P53350	PLK1	T509	G507E	507	Missense	proximal	-2	no	8.063	10.991	EPSD	COSMIC;GDSC;CCLE	10.919	Gain
Other_PLK_PLK1_PLK1_ST	O43663	PRC1	P53350	PLK1	S513	P519L	519	Missense	distal	6	no	11.022	10.918	EPSD	COSMIC	10.919	Loss
Other_PLK_PLK1_PLK1_ST	O43663	PRC1	P53350	PLK1	S513	F506I	506	Missense	distal	-7	no	11.022	11.017	EPSD	COSMIC	10.919	Down-regulation
Other_PLK_PLK1_PLK1_ST	O43663	PRC1	P53350	PLK1	S513	G507E	507	Missense	distal	-6	no	11.022	11.688	EPSD	COSMIC;GDSC;CCLE	10.919	Up-regulation
Other_PLK_PLK1_PLK1_ST	O43663	PRC1	P53350	PLK1	S554	G559W	559	Missense	distal	5	no	11.834	11.738	EPSD	COSMIC;GDSC;CCLE	10.919	Down-regulation
Other_PLK_PLK1_PLK1_ST	O43663	PRC1	P53350	PLK1	S554	G559V	559	Missense	distal	5	no	11.834	11.480	EPSD	COSMIC	10.919	Down-regulation
Other_PLK_PLK1_PLK1_ST	O43663	PRC1	P53350	PLK1	S587	S580F	580	Missense	distal	-7	no	14.025	13.568	EPSD	COSMIC	10.919	Down-regulation
Other_PLK_PLK1_PLK1_ST	O43663	PRC1	P53350	PLK1	S587	S589P	589	Missense	proximal	2	no	14.025	12.549	EPSD	COSMIC	10.919	Down-regulation
Other_PLK_PLK1_PLK1_ST	O43663	PRC1	P53350	PLK1	S601	Q597R	597	Missense	distal	-4	no	14.240	13.952	EPSD	COSMIC	10.919	Down-regulation
Other_PLK_PLK1_PLK1_ST	O43663	PRC1	P53350	PLK1	S601	A603V	603	Missense	proximal	2	no	14.240	14.683	EPSD	COSMIC	10.919	Up-regulation
Other_PLK_PLK1_PLK1_ST	O43663	PRC1	P53350	PLK1	S601	K602N	602	Missense	proximal	1	no	14.240	14.739	EPSD	COSMIC	10.919	Up-regulation
Other_PLK_PLK1_PLK1_ST	Q7L2Z9	CENPQ	P53350	PLK1	T135	K130N	130	Missense	distal	-5	no	11.453	11.254	EPSD;PhosphoSitePlus	COSMIC;GDSC;CCLE	10.919	Down-regulation
Other_PLK_PLK1_PLK1_ST	Q7L2Z9	CENPQ	P53350	PLK1	S138	R145K	145	Missense	distal	7	no	12.249	12.284	EPSD;PhosphoSitePlus	COSMIC	10.919	Up-regulation
Other_PLK_PLK1_PLK1_ST	Q7L2Z9	CENPQ	P53350	PLK1	S139	R145K	145	Missense	distal	6	no	10.825	11.185	EPSD;PhosphoSitePlus	COSMIC	10.919	Gain
Other_PLK_PLK1_PLK1_ST	Q7L2Z9	CENPQ	P53350	PLK1	T169	M165I	165	Missense	distal	-4	no	10.970	11.280	EPSD	COSMIC	10.919	Up-regulation
Other_PLK_PLK1_PLK1_ST	Q7L2Z9	CENPQ	P53350	PLK1	T169	K164E	164	Missense	distal	-5	no	10.970	10.727	EPSD	COSMIC	10.919	Loss
Other_PLK_PLK1_PLK1_ST	Q7L2Z9	CENPQ	P53350	PLK1	T169	I162V	162	Missense	distal	-7	no	10.970	11.136	EPSD	COSMIC	10.919	Up-regulation
Other_PLK_PLK1_PLK1_ST	Q7L2Z9	CENPQ	P53350	PLK1	T169	G174V	174	Missense	distal	5	no	10.970	10.616	EPSD	COSMIC	10.919	Loss
Other_PLK_PLK1_PLK1_ST	Q7L2Z9	CENPQ	P53350	PLK1	T173	G174V	174	Missense	proximal	1	no	12.399	13.030	EPSD	COSMIC	10.919	Up-regulation
Other_PLK_PLK1_PLK1_ST	Q7L2Z9	CENPQ	P53350	PLK1	T173	S178R	178	Missense	distal	5	no	12.399	12.744	EPSD	COSMIC	10.919	Up-regulation
Other_PLK_PLK1_PLK1_ST	Q7L2Z9	CENPQ	P53350	PLK1	S249	L245I	245	Missense	distal	-4	no	14.494	14.721	EPSD;PhosphoSitePlus	COSMIC	10.919	Up-regulation
Other_PLK_PLK1_PLK1_ST	Q7L2Z9	CENPQ	P53350	PLK1	S255	A261D	261	Missense	distal	6	no	11.102	11.090	PhosphoSitePlus;EPSD	COSMIC	10.919	Down-regulation
Other_PLK_PLK1_PLK1_ST	Q7L2Z9	CENPQ	P53350	PLK1	T256	A261D	261	Missense	distal	5	no	14.680	14.263	EPSD;PhosphoSitePlus	COSMIC	10.919	Down-regulation
Other_PLK_PLK1_PLK1_ST	Q8IZD2	KMT2E	P53350	PLK1	S499	K496N	496	Missense	distal	-3	no	12.233	12.052	EPSD	COSMIC	10.919	Down-regulation
Other_PLK_PLK1_PLK1_ST	Q8IZD2	KMT2E	P53350	PLK1	S499	D497V	497	Missense	proximal	-2	no	12.233	9.621	EPSD	COSMIC	10.919	Loss
Other_PLK_PLK1_PLK1_ST	Q8IZD2	KMT2E	P53350	PLK1	T510	T510A	510	Missense	central	0	yes	11.744	0.000	EPSD	COSMIC	10.919	Loss
Other_PLK_PLK1_PLK1_ST	Q8IZD2	KMT2E	P53350	PLK1	S861	P855S	855	Missense	distal	-6	no	12.329	12.953	PhosphoSitePlus	COSMIC	10.919	Up-regulation
Other_PLK_PLK1_PLK1_ST	Q8IZD2	KMT2E	P53350	PLK1	S909	T912M	912	Missense	distal	3	no	15.640	15.487	EPSD	COSMIC	10.919	Down-regulation
Other_PLK_PLK1_PLK1_ST	Q8IZD2	KMT2E	P53350	PLK1	S909	P905S	905	Missense	distal	-4	no	15.640	15.761	EPSD	COSMIC;GDSC;CCLE	10.919	Up-regulation
Other_PLK_PLK1_PLK1_ST	Q8IZD2	KMT2E	P53350	PLK1	S909	R915Q	915	Missense	distal	6	no	15.640	15.928	EPSD	COSMIC	10.919	Up-regulation
Other_PLK_PLK1_PLK1_ST	Q8IZD2	KMT2E	P53350	PLK1	S966	I960T	960	Missense	distal	-6	no	11.434	11.262	EPSD	COSMIC	10.919	Down-regulation
Other_PLK_PLK1_PLK1_ST	Q8IZD2	KMT2E	P53350	PLK1	T1062	R1060Q	1060	Missense	proximal	-2	no	11.152	10.976	EPSD	COSMIC;GDSC;CCLE	10.919	Down-regulation
Other_PLK_PLK1_PLK1_ST	Q8IZD2	KMT2E	P53350	PLK1	T1062	G1059E	1059	Missense	distal	-3	no	11.152	10.210	EPSD	COSMIC	10.919	Loss
Other_PLK_PLK1_PLK1_ST	Q8IZD2	KMT2E	P53350	PLK1	S1066	R1060Q	1060	Missense	distal	-6	no	11.645	12.092	EPSD	COSMIC;GDSC;CCLE	10.919	Up-regulation
Other_PLK_PLK1_PLK1_ST	Q8IZD2	KMT2E	P53350	PLK1	S1066	G1059E	1059	Missense	distal	-7	no	11.645	12.280	EPSD	COSMIC	10.919	Up-regulation
Other_PLK_PLK1_PLK1_ST	Q8IZD2	KMT2E	P53350	PLK1	T1088	S1090L	1090	Missense	proximal	2	no	11.129	11.201	EPSD	COSMIC	10.919	Up-regulation
Other_PLK_PLK1_PLK1_ST	Q8IZD2	KMT2E	P53350	PLK1	S1285	C1287Y	1287	Missense	proximal	2	no	10.953	11.558	EPSD	COSMIC	10.919	Up-regulation
Other_PLK_PLK1_PLK1_ST	Q8IZD2	KMT2E	P53350	PLK1	S1344	C1348S	1348	Missense	distal	4	no	11.998	12.525	EPSD	COSMIC	10.919	Up-regulation
Other_PLK_PLK1_PLK1_ST	Q8IZD2	KMT2E	P53350	PLK1	S1344	D1342G	1342	Missense	proximal	-2	no	11.998	8.676	EPSD	COSMIC	10.919	Loss
Other_PLK_PLK1_PLK1_ST	Q8IZD2	KMT2E	P53350	PLK1	S1344	E1337Q	1337	Missense	distal	-7	no	11.998	11.962	EPSD	COSMIC;GDSC	10.919	Down-regulation
Other_PLK_PLK1_PLK1_ST	Q8IZD2	KMT2E	P53350	PLK1	S1405	S1405L	1405	Missense	central	0	yes	11.614	0.000	EPSD	COSMIC	10.919	Loss
Other_PLK_PLK1_PLK1_ST	Q8IZD2	KMT2E	P53350	PLK1	S1466	K1468N	1468	Missense	proximal	2	no	10.560	11.535	EPSD	COSMIC	10.919	Gain
Other_PLK_PLK1_PLK1_ST	Q8IZD2	KMT2E	P53350	PLK1	S1466	P1467L	1467	Missense	proximal	1	no	10.560	11.406	EPSD	COSMIC	10.919	Gain
Other_PLK_PLK1_PLK1_ST	Q8IZD2	KMT2E	P53350	PLK1	S1466	K1468M	1468	Missense	proximal	2	no	10.560	11.319	EPSD	COSMIC	10.919	Gain
Other_PLK_PLK1_PLK1_ST	Q9Y6D9	MAD1L1	P53350	PLK1	T8	S12F	12	Missense	distal	4	no	12.736	11.922	EPSD	COSMIC	10.919	Down-regulation
Other_PLK_PLK1_PLK1_ST	Q9Y6D9	MAD1L1	P53350	PLK1	S22	F20L	20	Missense	proximal	-2	no	10.339	10.949	EPSD;PhosphoSitePlus	COSMIC	10.919	Gain
Other_PLK_PLK1_PLK1_ST	Q9Y6D9	MAD1L1	P53350	PLK1	S266	R270W	270	Missense	distal	4	no	10.848	11.387	EPSD	COSMIC;GDSC	10.919	Gain
Other_PLK_PLK1_PLK1_ST	Q9Y6D9	MAD1L1	P53350	PLK1	S266	A267T	267	Missense	proximal	1	no	10.848	11.310	EPSD	COSMIC	10.919	Gain
Other_PLK_PLK1_PLK1_ST	Q9Y6D9	MAD1L1	P53350	PLK1	T323	G325D	325	Missense	proximal	2	no	9.713	11.292	EPSD	COSMIC	10.919	Gain
Other_PLK_PLK1_PLK1_ST	Q9Y6D9	MAD1L1	P53350	PLK1	S327	G325D	325	Missense	proximal	-2	no	7.755	11.077	EPSD	COSMIC	10.919	Gain
Other_PLK_PLK1_PLK1_ST	Q9Y6D9	MAD1L1	P53350	PLK1	S420	Y418H	418	Missense	proximal	-2	no	13.823	12.178	EPSD	COSMIC	10.919	Down-regulation
Other_PLK_PLK1_PLK1_ST	Q9Y6D9	MAD1L1	P53350	PLK1	S420	D419G	419	Missense	proximal	-1	no	13.823	11.233	EPSD	COSMIC	10.919	Down-regulation
Other_PLK_PLK1_PLK1_ST	Q9Y6D9	MAD1L1	P53350	PLK1	S420	E421D	421	Missense	proximal	1	no	13.823	14.067	EPSD	COSMIC	10.919	Up-regulation
Other_PLK_PLK1_PLK1_ST	Q9Y6D9	MAD1L1	P53350	PLK1	S420	P424Q	424	Missense	distal	4	no	13.823	13.730	EPSD	COSMIC	10.919	Down-regulation
Other_PLK_PLK1_PLK1_ST	Q9Y6D9	MAD1L1	P53350	PLK1	S420	P424T	424	Missense	distal	4	no	13.823	13.953	EPSD	COSMIC	10.919	Up-regulation
Other_PLK_PLK1_PLK1_ST	Q9Y6D9	MAD1L1	P53350	PLK1	S428	T432M	432	Missense	distal	4	no	13.971	13.214	EPSD	COSMIC	10.919	Down-regulation
Other_PLK_PLK1_PLK1_ST	Q9Y6D9	MAD1L1	P53350	PLK1	S428	R433W	433	Missense	distal	5	no	13.971	13.713	EPSD	COSMIC	10.919	Down-regulation
Other_PLK_PLK1_PLK1_ST	Q9Y6D9	MAD1L1	P53350	PLK1	S428	E421D	421	Missense	distal	-7	no	13.971	13.682	EPSD	COSMIC	10.919	Down-regulation
Other_PLK_PLK1_PLK1_ST	Q9Y6D9	MAD1L1	P53350	PLK1	S428	P424Q	424	Missense	distal	-4	no	13.971	13.815	EPSD	COSMIC	10.919	Down-regulation
Other_PLK_PLK1_PLK1_ST	Q9Y6D9	MAD1L1	P53350	PLK1	S428	P424T	424	Missense	distal	-4	no	13.971	13.731	EPSD	COSMIC	10.919	Down-regulation
Other_PLK_PLK1_PLK1_ST	Q9Y6D9	MAD1L1	P53350	PLK1	S447	A450T	450	Missense	distal	3	no	11.041	11.080	EPSD	COSMIC	10.919	Up-regulation
Other_PLK_PLK1_PLK1_ST	Q9Y6D9	MAD1L1	P53350	PLK1	S447	S449C	449	Missense	proximal	2	no	11.041	10.069	EPSD	COSMIC	10.919	Loss
Other_PLK_PLK1_PLK1_ST	Q9Y6D9	MAD1L1	P53350	PLK1	S490	S485C	485	Missense	distal	-5	no	14.341	14.359	EPSD	COSMIC	10.919	Up-regulation
Other_PLK_PLK1_PLK1_ST	Q9Y6D9	MAD1L1	P53350	PLK1	S490	F493L	493	Missense	distal	3	no	14.341	14.135	EPSD	COSMIC	10.919	Down-regulation
Other_PLK_PLK1_PLK1_ST	Q9Y6D9	MAD1L1	P53350	PLK1	S490	E496D	496	Missense	distal	6	no	14.341	14.491	EPSD	COSMIC;GDSC;CCLE	10.919	Up-regulation
Other_PLK_PLK1_PLK1_ST	Q9Y6D9	MAD1L1	P53350	PLK1	S546	R539W	539	Missense	distal	-7	no	13.046	13.632	EPSD	COSMIC	10.919	Up-regulation
Other_PLK_PLK1_PLK1_ST	Q9Y6D9	MAD1L1	P53350	PLK1	S562	R558H	558	Missense	distal	-4	no	10.942	11.243	EPSD	COSMIC	10.919	Up-regulation
Other_PLK_PLK1_PLK1_ST	Q9Y6D9	MAD1L1	P53350	PLK1	S562	E559K	559	Missense	distal	-3	no	10.942	11.482	EPSD	COSMIC	10.919	Up-regulation
Other_PLK_PLK1_PLK1_ST	Q9Y6D9	MAD1L1	P53350	PLK1	T624	K625M	625	Missense	proximal	1	no	8.747	11.230	EPSD	COSMIC	10.919	Gain
Other_PLK_PLK1_PLK1_ST	Q9Y6D9	MAD1L1	P53350	PLK1	S699	S705G	705	Missense	distal	6	no	10.982	10.778	EPSD	COSMIC	10.919	Loss
Other_PLK_PLK1_PLK1_ST	Q9Y6D9	MAD1L1	P53350	PLK1	S699	L704I	704	Missense	distal	5	no	10.982	11.626	EPSD	COSMIC	10.919	Up-regulation
Other_PLK_PLK1_PLK1_ST	Q9Y6D9	MAD1L1	P53350	PLK1	S699	R695W	695	Missense	distal	-4	no	10.982	11.397	EPSD	COSMIC	10.919	Up-regulation
Other_PLK_PLK1_PLK1_ST	Q99708	RBBP8	P53350	PLK1	S17	L23I	23	Missense	distal	6	no	12.525	12.487	EPSD	COSMIC	10.919	Down-regulation
Other_PLK_PLK1_PLK1_ST	Q99708	RBBP8	P53350	PLK1	S17	K21N	21	Missense	distal	4	no	12.525	12.674	EPSD	COSMIC	10.919	Up-regulation
Other_PLK_PLK1_PLK1_ST	Q99708	RBBP8	P53350	PLK1	S269	S276N	276	Missense	distal	7	no	10.885	10.940	EPSD	COSMIC	10.919	Gain
Other_PLK_PLK1_PLK1_ST	Q99708	RBBP8	P53350	PLK1	S276	S276N	276	Missense	central	0	yes	11.817	0.000	EPSD	COSMIC	10.919	Loss
Other_PLK_PLK1_PLK1_ST	Q99708	RBBP8	P53350	PLK1	S335	G331V	331	Missense	distal	-4	no	10.515	11.068	EPSD	COSMIC	10.919	Gain
Other_PLK_PLK1_PLK1_ST	Q99708	RBBP8	P53350	PLK1	S349	G354V	354	Missense	distal	5	no	11.566	11.212	EPSD	COSMIC	10.919	Down-regulation
Other_PLK_PLK1_PLK1_ST	Q99708	RBBP8	P53350	PLK1	S649	S649P	649	Missense	central	0	yes	11.567	0.000	EPSD	COSMIC	10.919	Loss
Other_PLK_PLK1_PLK1_ST	Q99708	RBBP8	P53350	PLK1	S664	D662H	662	Missense	proximal	-2	no	14.730	11.543	EPSD	COSMIC	10.919	Down-regulation
Other_PLK_PLK1_PLK1_ST	Q99708	RBBP8	P53350	PLK1	S723	R730W	730	Missense	distal	7	no	11.967	11.986	PhosphoSitePlus;EPSD	COSMIC	10.919	Up-regulation
Other_PLK_PLK1_PLK1_ST	Q99708	RBBP8	P53350	PLK1	S743	E737D	737	Missense	distal	-6	no	13.958	13.756	EPSD	COSMIC	10.919	Down-regulation
Other_PLK_PLK1_PLK1_ST	Q99708	RBBP8	P53350	PLK1	S743	D742N	742	Missense	proximal	-1	no	13.958	13.025	EPSD	COSMIC	10.919	Down-regulation
Other_PLK_PLK1_PLK1_ST	Q99708	RBBP8	P53350	PLK1	S743	S745C	745	Missense	proximal	2	no	13.958	12.986	EPSD	COSMIC	10.919	Down-regulation
Other_PLK_PLK1_PLK1_ST	Q99708	RBBP8	P53350	PLK1	S789	S789C	789	Missense	central	0	yes	11.693	0.000	EPSD;PhosphoSitePlus	COSMIC	10.919	Loss
Other_PLK_PLK1_PLK1_ST	Q99708	RBBP8	P53350	PLK1	S789	P794S	794	Missense	distal	5	no	11.693	11.306	EPSD;PhosphoSitePlus	COSMIC	10.919	Down-regulation
Other_PLK_PLK1_PLK1_ST	Q15022	SUZ12	P53350	PLK1	S382	E383V	383	Missense	proximal	1	no	10.598	11.475	EPSD	COSMIC	10.919	Gain
Other_PLK_PLK1_PLK1_ST	Q15022	SUZ12	P53350	PLK1	S384	E383V	383	Missense	proximal	-1	no	12.886	11.933	EPSD	COSMIC	10.919	Down-regulation
Other_PLK_PLK1_PLK1_ST	Q15022	SUZ12	P53350	PLK1	S462	R458H	458	Missense	distal	-4	no	11.249	11.551	EPSD	COSMIC	10.919	Up-regulation
Other_PLK_PLK1_PLK1_ST	Q15022	SUZ12	P53350	PLK1	S539	M540I	540	Missense	proximal	1	no	11.510	10.545	EPSD;PhosphoSitePlus	COSMIC	10.919	Loss
Other_PLK_PLK1_PLK1_ST	Q15022	SUZ12	P53350	PLK1	S583	V581E	581	Missense	proximal	-2	no	10.789	13.007	EPSD	COSMIC	10.919	Gain
Other_PLK_PLK1_PLK1_ST	Q15022	SUZ12	P53350	PLK1	S583	M579I	579	Missense	distal	-4	no	10.789	11.098	EPSD	COSMIC	10.919	Gain
Other_PLK_PLK1_PLK1_ST	Q15022	SUZ12	P53350	PLK1	S604	G609R	609	Missense	distal	5	no	11.616	11.778	EPSD	COSMIC	10.919	Up-regulation
Other_PLK_PLK1_PLK1_ST	Q15022	SUZ12	P53350	PLK1	S604	D605V	605	Missense	proximal	1	no	11.616	12.249	EPSD	COSMIC	10.919	Up-regulation
Other_PLK_PLK1_PLK1_ST	Q15022	SUZ12	P53350	PLK1	S726	V730A	730	Missense	distal	4	no	13.282	13.546	EPSD	COSMIC;CCLE	10.919	Up-regulation
Other_PLK_PLK1_PLK1_ST	Q9BVS4	RIOK2	P53350	PLK1	S335	S332Y	332	Missense	distal	-3	no	14.806	15.275	PhosphoSitePlus;EPSD	COSMIC	10.919	Up-regulation
Other_PLK_PLK1_PLK1_ST	Q9BVS4	RIOK2	P53350	PLK1	S335	A342V	342	Missense	distal	7	no	14.806	14.829	PhosphoSitePlus;EPSD	COSMIC	10.919	Up-regulation
Other_PLK_PLK1_PLK1_ST	Q9BVS4	RIOK2	P53350	PLK1	S380	D379G	379	Missense	proximal	-1	no	14.193	11.603	EPSD;PhosphoSitePlus	COSMIC	10.919	Down-regulation
Other_PLK_PLK1_PLK1_ST	Q14676	MDC1	P53350	PLK1	S202	G200E	200	Missense	proximal	-2	no	9.285	12.213	EPSD	COSMIC	10.919	Gain
Other_PLK_PLK1_PLK1_ST	Q14676	MDC1	P53350	PLK1	S292	L289V	289	Missense	distal	-3	no	10.929	10.279	EPSD	COSMIC	10.919	Loss
Other_PLK_PLK1_PLK1_ST	Q14676	MDC1	P53350	PLK1	S292	P295S	295	Missense	distal	3	no	10.929	10.908	EPSD	COSMIC	10.919	Loss
Other_PLK_PLK1_PLK1_ST	Q14676	MDC1	P53350	PLK1	S292	P295L	295	Missense	distal	3	no	10.929	10.761	EPSD	COSMIC	10.919	Loss
Other_PLK_PLK1_PLK1_ST	Q14676	MDC1	P53350	PLK1	S299	P295S	295	Missense	distal	-4	no	11.763	11.885	EPSD	COSMIC	10.919	Up-regulation
Other_PLK_PLK1_PLK1_ST	Q14676	MDC1	P53350	PLK1	S299	V303L	303	Missense	distal	4	no	11.763	11.613	EPSD	COSMIC	10.919	Down-regulation
Other_PLK_PLK1_PLK1_ST	Q14676	MDC1	P53350	PLK1	S299	P295L	295	Missense	distal	-4	no	11.763	11.692	EPSD	COSMIC	10.919	Down-regulation
Other_PLK_PLK1_PLK1_ST	Q14676	MDC1	P53350	PLK1	S307	R308M	308	Missense	proximal	1	no	9.702	13.590	EPSD	COSMIC;GDSC;CCLE	10.919	Gain
Other_PLK_PLK1_PLK1_ST	Q14676	MDC1	P53350	PLK1	S372	Q370R	370	Missense	proximal	-2	no	11.301	11.477	EPSD	COSMIC	10.919	Up-regulation
Other_PLK_PLK1_PLK1_ST	Q14676	MDC1	P53350	PLK1	S372	Q373L	373	Missense	proximal	1	no	11.301	12.454	EPSD	COSMIC	10.919	Up-regulation
Other_PLK_PLK1_PLK1_ST	Q14676	MDC1	P53350	PLK1	T378	A385T	385	Missense	distal	7	no	13.390	13.349	EPSD	COSMIC	10.919	Down-regulation
Other_PLK_PLK1_PLK1_ST	Q14676	MDC1	P53350	PLK1	T378	Q373L	373	Missense	distal	-5	no	13.390	14.109	EPSD	COSMIC	10.919	Up-regulation
Other_PLK_PLK1_PLK1_ST	Q14676	MDC1	P53350	PLK1	T378	G383C	383	Missense	distal	5	no	13.390	13.336	EPSD	COSMIC	10.919	Down-regulation
Other_PLK_PLK1_PLK1_ST	Q14676	MDC1	P53350	PLK1	S394	A388V	388	Missense	distal	-6	no	13.136	12.897	EPSD	COSMIC	10.919	Down-regulation
Other_PLK_PLK1_PLK1_ST	Q14676	MDC1	P53350	PLK1	S394	E392K	392	Missense	proximal	-2	no	13.136	10.259	EPSD	COSMIC	10.919	Loss
Other_PLK_PLK1_PLK1_ST	Q14676	MDC1	P53350	PLK1	S402	E407A	407	Missense	distal	5	no	10.774	11.633	EPSD	COSMIC	10.919	Gain
Other_PLK_PLK1_PLK1_ST	Q14676	MDC1	P53350	PLK1	S485	F492V	492	Missense	distal	7	no	10.999	10.978	EPSD	COSMIC	10.919	Down-regulation
Other_PLK_PLK1_PLK1_ST	Q14676	MDC1	P53350	PLK1	S485	E486K	486	Missense	proximal	1	no	10.999	10.549	EPSD	COSMIC	10.919	Loss
Other_PLK_PLK1_PLK1_ST	Q14676	MDC1	P53350	PLK1	S498	F492V	492	Missense	distal	-6	no	13.110	13.353	EPSD	COSMIC	10.919	Up-regulation
Other_PLK_PLK1_PLK1_ST	Q14676	MDC1	P53350	PLK1	S498	D496N	496	Missense	proximal	-2	no	13.110	11.868	EPSD	COSMIC	10.919	Down-regulation
Other_PLK_PLK1_PLK1_ST	Q14676	MDC1	P53350	PLK1	S498	D502Y	502	Missense	distal	4	no	13.110	12.864	EPSD	COSMIC	10.919	Down-regulation
Other_PLK_PLK1_PLK1_ST	Q14676	MDC1	P53350	PLK1	S504	H509P	509	Missense	distal	5	no	10.335	11.028	EPSD	COSMIC	10.919	Gain
Other_PLK_PLK1_PLK1_ST	Q14676	MDC1	P53350	PLK1	S513	H509P	509	Missense	distal	-4	no	10.946	11.089	EPSD	COSMIC	10.919	Up-regulation
Other_PLK_PLK1_PLK1_ST	Q14676	MDC1	P53350	PLK1	S763	S763F	763	Missense	central	0	yes	11.461	0.000	EPSD	COSMIC;GDSC;CCLE	10.919	Loss
Other_PLK_PLK1_PLK1_ST	Q14676	MDC1	P53350	PLK1	T847	R842S	842	Missense	distal	-5	no	11.387	10.703	EPSD;PhosphoSitePlus	COSMIC	10.919	Loss
Other_PLK_PLK1_PLK1_ST	Q14676	MDC1	P53350	PLK1	T847	E850G	850	Missense	distal	3	no	11.387	11.210	EPSD;PhosphoSitePlus	COSMIC	10.919	Down-regulation
Other_PLK_PLK1_PLK1_ST	Q14676	MDC1	P53350	PLK1	T847	D845N	845	Missense	proximal	-2	no	11.387	10.145	EPSD;PhosphoSitePlus	COSMIC	10.919	Loss
Other_PLK_PLK1_PLK1_ST	Q14676	MDC1	P53350	PLK1	T847	E850K	850	Missense	distal	3	no	11.387	11.181	EPSD;PhosphoSitePlus	COSMIC	10.919	Down-regulation
Other_PLK_PLK1_PLK1_ST	Q14676	MDC1	P53350	PLK1	S1154	V1155L	1155	Missense	proximal	1	no	12.355	12.755	EPSD	COSMIC	10.919	Up-regulation
Other_PLK_PLK1_PLK1_ST	Q14676	MDC1	P53350	PLK1	S1154	P1160L	1160	Missense	distal	6	no	12.355	12.251	EPSD	COSMIC	10.919	Down-regulation
Other_PLK_PLK1_PLK1_ST	Q14676	MDC1	P53350	PLK1	S1195	S1194F	1194	Missense	proximal	-1	no	11.095	10.556	EPSD	COSMIC	10.919	Loss
Other_PLK_PLK1_PLK1_ST	Q14676	MDC1	P53350	PLK1	S1195	S1192N	1192	Missense	distal	-3	no	11.095	11.285	EPSD	COSMIC	10.919	Up-regulation
Other_PLK_PLK1_PLK1_ST	Q14676	MDC1	P53350	PLK1	S1195	T1198I	1198	Missense	distal	3	no	11.095	11.262	EPSD	COSMIC	10.919	Up-regulation
Other_PLK_PLK1_PLK1_ST	Q14676	MDC1	P53350	PLK1	S1195	V1196I	1196	Missense	proximal	1	no	11.095	11.286	EPSD	COSMIC	10.919	Up-regulation
Other_PLK_PLK1_PLK1_ST	Q14676	MDC1	P53350	PLK1	S1212	R1217Q	1217	Missense	distal	5	no	11.789	10.994	EPSD	COSMIC	10.919	Down-regulation
Other_PLK_PLK1_PLK1_ST	Q14676	MDC1	P53350	PLK1	S1212	T1213A	1213	Missense	proximal	1	no	11.789	11.327	EPSD	COSMIC	10.919	Down-regulation
Other_PLK_PLK1_PLK1_ST	Q14676	MDC1	P53350	PLK1	S1212	E1208K	1208	Missense	distal	-4	no	11.789	11.406	EPSD	COSMIC	10.919	Down-regulation
Other_PLK_PLK1_PLK1_ST	Q14676	MDC1	P53350	PLK1	S1212	T1215I	1215	Missense	distal	3	no	11.789	11.956	EPSD	COSMIC	10.919	Up-regulation
Other_PLK_PLK1_PLK1_ST	Q14676	MDC1	P53350	PLK1	S1236	R1229M	1229	Missense	distal	-7	no	11.470	11.537	EPSD	COSMIC	10.919	Up-regulation
Other_PLK_PLK1_PLK1_ST	Q14676	MDC1	P53350	PLK1	T1265	Y1266S	1266	Missense	proximal	1	no	10.965	10.227	EPSD	COSMIC	10.919	Loss
Other_PLK_PLK1_PLK1_ST	Q14676	MDC1	P53350	PLK1	T1265	P1259S	1259	Missense	distal	-6	no	10.965	11.589	EPSD	COSMIC;GDSC	10.919	Up-regulation
Other_PLK_PLK1_PLK1_ST	Q14676	MDC1	P53350	PLK1	T1265	A1268V	1268	Missense	distal	3	no	10.965	11.293	EPSD	COSMIC	10.919	Up-regulation
Other_PLK_PLK1_PLK1_ST	Q14676	MDC1	P53350	PLK1	T1265	Y1266F	1266	Missense	proximal	1	no	10.965	13.276	EPSD	COSMIC	10.919	Up-regulation
Other_PLK_PLK1_PLK1_ST	Q14676	MDC1	P53350	PLK1	T1265	R1272T	1272	Missense	distal	7	no	10.965	10.935	EPSD	COSMIC	10.919	Down-regulation
Other_PLK_PLK1_PLK1_ST	Q14676	MDC1	P53350	PLK1	T1265	G1271R	1271	Missense	distal	6	no	10.965	10.863	EPSD	COSMIC	10.919	Loss
Other_PLK_PLK1_PLK1_ST	Q14676	MDC1	P53350	PLK1	S1276	S1277F	1277	Missense	proximal	1	no	9.298	12.346	EPSD	COSMIC	10.919	Gain
Other_PLK_PLK1_PLK1_ST	Q14676	MDC1	P53350	PLK1	S1277	P1283T	1283	Missense	distal	6	no	11.426	11.558	EPSD	COSMIC	10.919	Up-regulation
Other_PLK_PLK1_PLK1_ST	Q14676	MDC1	P53350	PLK1	S1277	N1274S	1274	Missense	distal	-3	no	11.426	11.236	EPSD	COSMIC	10.919	Down-regulation
Other_PLK_PLK1_PLK1_ST	Q14676	MDC1	P53350	PLK1	S1277	R1272T	1272	Missense	distal	-5	no	11.426	10.957	EPSD	COSMIC	10.919	Down-regulation
Other_PLK_PLK1_PLK1_ST	Q14676	MDC1	P53350	PLK1	S1277	S1277F	1277	Missense	central	0	yes	11.426	0.000	EPSD	COSMIC	10.919	Loss
Other_PLK_PLK1_PLK1_ST	Q14676	MDC1	P53350	PLK1	S1277	G1271R	1271	Missense	distal	-6	no	11.426	11.525	EPSD	COSMIC	10.919	Up-regulation
Other_PLK_PLK1_PLK1_ST	Q14676	MDC1	P53350	PLK1	S1294	P1300L	1300	Missense	distal	6	no	12.009	11.904	EPSD	COSMIC	10.919	Down-regulation
Other_PLK_PLK1_PLK1_ST	Q14676	MDC1	P53350	PLK1	S1317	S1318F	1318	Missense	proximal	1	no	11.780	14.828	EPSD	COSMIC	10.919	Up-regulation
Other_PLK_PLK1_PLK1_ST	Q14676	MDC1	P53350	PLK1	S1317	R1311M	1311	Missense	distal	-6	no	11.780	12.109	EPSD	COSMIC	10.919	Up-regulation
Other_PLK_PLK1_PLK1_ST	Q14676	MDC1	P53350	PLK1	S1317	T1324P	1324	Missense	distal	7	no	11.780	11.822	EPSD	COSMIC	10.919	Up-regulation
Other_PLK_PLK1_PLK1_ST	Q14676	MDC1	P53350	PLK1	S1317	M1316V	1316	Missense	proximal	-1	no	11.780	10.751	EPSD	COSMIC	10.919	Loss
Other_PLK_PLK1_PLK1_ST	Q14676	MDC1	P53350	PLK1	S1317	S1318A	1318	Missense	proximal	1	no	11.780	11.910	EPSD	COSMIC	10.919	Up-regulation
Other_PLK_PLK1_PLK1_ST	Q14676	MDC1	P53350	PLK1	S1317	M1316T	1316	Missense	proximal	-1	no	11.780	10.961	EPSD	COSMIC	10.919	Down-regulation
Other_PLK_PLK1_PLK1_ST	Q14676	MDC1	P53350	PLK1	S1318	S1318F	1318	Missense	central	0	yes	12.733	0.000	EPSD	COSMIC	10.919	Loss
Other_PLK_PLK1_PLK1_ST	Q14676	MDC1	P53350	PLK1	S1318	R1311M	1311	Missense	distal	-7	no	12.733	12.800	EPSD	COSMIC	10.919	Up-regulation
Other_PLK_PLK1_PLK1_ST	Q14676	MDC1	P53350	PLK1	S1318	T1324P	1324	Missense	distal	6	no	12.733	12.602	EPSD	COSMIC	10.919	Down-regulation
Other_PLK_PLK1_PLK1_ST	Q14676	MDC1	P53350	PLK1	S1318	M1316V	1316	Missense	proximal	-2	no	12.733	13.229	EPSD	COSMIC	10.919	Up-regulation
Other_PLK_PLK1_PLK1_ST	Q14676	MDC1	P53350	PLK1	S1318	S1318A	1318	Missense	central	0	yes	12.733	0.000	EPSD	COSMIC	10.919	Loss
Other_PLK_PLK1_PLK1_ST	Q14676	MDC1	P53350	PLK1	S1318	M1316T	1316	Missense	proximal	-2	no	12.733	12.651	EPSD	COSMIC	10.919	Down-regulation
Other_PLK_PLK1_PLK1_ST	Q14676	MDC1	P53350	PLK1	T1324	S1318F	1318	Missense	distal	-6	no	11.558	11.041	EPSD	COSMIC	10.919	Down-regulation
Other_PLK_PLK1_PLK1_ST	Q14676	MDC1	P53350	PLK1	T1324	T1324P	1324	Missense	central	0	yes	11.558	0.000	EPSD	COSMIC	10.919	Loss
Other_PLK_PLK1_PLK1_ST	Q14676	MDC1	P53350	PLK1	T1324	S1318A	1318	Missense	distal	-6	no	11.558	11.522	EPSD	COSMIC	10.919	Down-regulation
Other_PLK_PLK1_PLK1_ST	Q14676	MDC1	P53350	PLK1	T1324	P1330S	1330	Missense	distal	6	no	11.558	11.414	EPSD	COSMIC	10.919	Down-regulation
Other_PLK_PLK1_PLK1_ST	Q14676	MDC1	P53350	PLK1	T1324	P1327R	1327	Missense	distal	3	no	11.558	11.412	EPSD	COSMIC	10.919	Down-regulation
Other_PLK_PLK1_PLK1_ST	Q14676	MDC1	P53350	PLK1	S1335	I1334T	1334	Missense	proximal	-1	no	12.729	11.965	EPSD	COSMIC	10.919	Down-regulation
Other_PLK_PLK1_PLK1_ST	Q14676	MDC1	P53350	PLK1	S1335	T1336P	1336	Missense	proximal	1	no	12.729	13.258	EPSD	COSMIC	10.919	Up-regulation
Other_PLK_PLK1_PLK1_ST	Q14676	MDC1	P53350	PLK1	S1335	Q1340R	1340	Missense	distal	5	no	12.729	13.525	EPSD	COSMIC	10.919	Up-regulation
Other_PLK_PLK1_PLK1_ST	Q14676	MDC1	P53350	PLK1	S1335	P1330S	1330	Missense	distal	-5	no	12.729	12.467	EPSD	COSMIC	10.919	Down-regulation
Other_PLK_PLK1_PLK1_ST	Q14676	MDC1	P53350	PLK1	T1366	P1371H	1371	Missense	distal	5	no	11.738	11.045	EPSD	COSMIC	10.919	Down-regulation
Other_PLK_PLK1_PLK1_ST	Q14676	MDC1	P53350	PLK1	T1366	P1363S	1363	Missense	distal	-3	no	11.738	12.156	EPSD	COSMIC	10.919	Up-regulation
Other_PLK_PLK1_PLK1_ST	Q14676	MDC1	P53350	PLK1	T1366	V1360M	1360	Missense	distal	-6	no	11.738	11.895	EPSD	COSMIC	10.919	Up-regulation
Other_PLK_PLK1_PLK1_ST	Q14676	MDC1	P53350	PLK1	T1406	P1409L	1409	Missense	distal	3	no	11.265	11.097	EPSD	COSMIC	10.919	Down-regulation
Other_PLK_PLK1_PLK1_ST	Q14676	MDC1	P53350	PLK1	T1406	G1401C	1401	Missense	distal	-5	no	11.265	10.885	EPSD	COSMIC	10.919	Loss
Other_PLK_PLK1_PLK1_ST	Q14676	MDC1	P53350	PLK1	S1417	E1415K	1415	Missense	proximal	-2	no	12.617	9.740	EPSD	COSMIC	10.919	Loss
Other_PLK_PLK1_PLK1_ST	Q14676	MDC1	P53350	PLK1	S1440	R1434S	1434	Missense	distal	-6	no	10.511	10.958	EPSD	COSMIC	10.919	Gain
Other_PLK_PLK1_PLK1_ST	Q14676	MDC1	P53350	PLK1	S1441	R1439K	1439	Missense	proximal	-2	no	10.987	10.594	EPSD	COSMIC	10.919	Loss
Other_PLK_PLK1_PLK1_ST	Q14676	MDC1	P53350	PLK1	S1441	R1434S	1434	Missense	distal	-7	no	10.987	11.484	EPSD	COSMIC	10.919	Up-regulation
Other_PLK_PLK1_PLK1_ST	Q14676	MDC1	P53350	PLK1	S1441	R1436T	1436	Missense	distal	-5	no	10.987	10.518	EPSD	COSMIC	10.919	Loss
Other_PLK_PLK1_PLK1_ST	Q14676	MDC1	P53350	PLK1	S1458	T1459P	1459	Missense	proximal	1	no	10.656	11.186	EPSD	COSMIC	10.919	Gain
Other_PLK_PLK1_PLK1_ST	Q14676	MDC1	P53350	PLK1	S1481	T1488R	1488	Missense	distal	7	no	11.337	11.367	EPSD	COSMIC	10.919	Up-regulation
Other_PLK_PLK1_PLK1_ST	Q14676	MDC1	P53350	PLK1	S1481	V1483I	1483	Missense	proximal	2	no	11.337	11.554	EPSD	COSMIC	10.919	Up-regulation
Other_PLK_PLK1_PLK1_ST	Q14676	MDC1	P53350	PLK1	S1481	T1488P	1488	Missense	distal	7	no	11.337	11.379	EPSD	COSMIC	10.919	Up-regulation
Other_PLK_PLK1_PLK1_ST	Q14676	MDC1	P53350	PLK1	S1481	D1479H	1479	Missense	proximal	-2	no	11.337	8.150	EPSD	COSMIC	10.919	Loss
Other_PLK_PLK1_PLK1_ST	Q14676	MDC1	P53350	PLK1	S1481	P1486T	1486	Missense	distal	5	no	11.337	10.345	EPSD	COSMIC	10.919	Loss
Other_PLK_PLK1_PLK1_ST	Q14676	MDC1	P53350	PLK1	S1482	V1483I	1483	Missense	proximal	1	no	10.915	11.106	EPSD	COSMIC	10.919	Gain
Other_PLK_PLK1_PLK1_ST	Q14676	MDC1	P53350	PLK1	S1482	P1486T	1486	Missense	distal	4	no	10.915	11.045	EPSD	COSMIC	10.919	Gain
Other_PLK_PLK1_PLK1_ST	Q14676	MDC1	P53350	PLK1	T1488	P1494H	1494	Missense	distal	6	no	11.900	11.233	EPSD	COSMIC	10.919	Down-regulation
Other_PLK_PLK1_PLK1_ST	Q14676	MDC1	P53350	PLK1	T1488	T1488R	1488	Missense	central	0	yes	11.900	0.000	EPSD	COSMIC	10.919	Loss
Other_PLK_PLK1_PLK1_ST	Q14676	MDC1	P53350	PLK1	T1488	V1483I	1483	Missense	distal	-5	no	11.900	12.058	EPSD	COSMIC	10.919	Up-regulation
Other_PLK_PLK1_PLK1_ST	Q14676	MDC1	P53350	PLK1	T1488	T1488P	1488	Missense	central	0	yes	11.900	0.000	EPSD	COSMIC	10.919	Loss
Other_PLK_PLK1_PLK1_ST	Q14676	MDC1	P53350	PLK1	T1488	P1486T	1486	Missense	proximal	-2	no	11.900	11.946	EPSD	COSMIC	10.919	Up-regulation
Other_PLK_PLK1_PLK1_ST	Q14676	MDC1	P53350	PLK1	T1488	S1481T	1481	Missense	distal	-7	no	11.900	11.891	EPSD	COSMIC	10.919	Down-regulation
Other_PLK_PLK1_PLK1_ST	Q14676	MDC1	P53350	PLK1	S1499	P1494H	1494	Missense	distal	-5	no	11.161	10.779	EPSD	COSMIC	10.919	Loss
Other_PLK_PLK1_PLK1_ST	Q14676	MDC1	P53350	PLK1	S1499	A1500T	1500	Missense	proximal	1	no	11.161	11.623	EPSD	COSMIC	10.919	Up-regulation
Other_PLK_PLK1_PLK1_ST	Q14676	MDC1	P53350	PLK1	S1499	D1503N	1503	Missense	distal	4	no	11.161	10.922	EPSD	COSMIC	10.919	Down-regulation
Other_PLK_PLK1_PLK1_ST	Q14676	MDC1	P53350	PLK1	S1522	R1521W	1521	Missense	proximal	-1	no	11.593	10.303	EPSD	COSMIC	10.919	Loss
Other_PLK_PLK1_PLK1_ST	Q14676	MDC1	P53350	PLK1	S1523	R1521W	1521	Missense	proximal	-2	no	11.802	5.143	EPSD	COSMIC	10.919	Loss
Other_PLK_PLK1_PLK1_ST	Q14676	MDC1	P53350	PLK1	S1540	A1533E	1533	Missense	distal	-7	no	10.688	10.981	EPSD	COSMIC	10.919	Gain
Other_PLK_PLK1_PLK1_ST	Q14676	MDC1	P53350	PLK1	S1563	T1556N	1556	Missense	distal	-7	no	10.963	10.762	EPSD	COSMIC	10.919	Loss
Other_PLK_PLK1_PLK1_ST	Q14676	MDC1	P53350	PLK1	S1563	R1562T	1562	Missense	proximal	-1	no	10.963	11.152	EPSD	COSMIC	10.919	Up-regulation
Other_PLK_PLK1_PLK1_ST	Q14676	MDC1	P53350	PLK1	S1563	G1558C	1558	Missense	distal	-5	no	10.963	10.583	EPSD	COSMIC	10.919	Loss
Other_PLK_PLK1_PLK1_ST	Q14676	MDC1	P53350	PLK1	S1563	R1562M	1562	Missense	proximal	-1	no	10.963	11.971	EPSD	COSMIC	10.919	Up-regulation
Other_PLK_PLK1_PLK1_ST	Q14676	MDC1	P53350	PLK1	S1564	R1562T	1562	Missense	proximal	-2	no	11.022	10.709	EPSD	COSMIC	10.919	Loss
Other_PLK_PLK1_PLK1_ST	Q14676	MDC1	P53350	PLK1	S1564	G1558C	1558	Missense	distal	-6	no	11.022	10.365	EPSD	COSMIC	10.919	Loss
Other_PLK_PLK1_PLK1_ST	Q14676	MDC1	P53350	PLK1	S1564	R1562M	1562	Missense	proximal	-2	no	11.022	10.792	EPSD	COSMIC	10.919	Loss
Other_PLK_PLK1_PLK1_ST	Q14676	MDC1	P53350	PLK1	S1658	P1662S	1662	Missense	distal	4	no	10.824	11.146	EPSD	COSMIC	10.919	Gain
Other_PLK_PLK1_PLK1_ST	Q14676	MDC1	P53350	PLK1	S1658	L1660I	1660	Missense	proximal	2	no	10.824	11.174	EPSD	COSMIC	10.919	Gain
Other_PLK_PLK1_PLK1_ST	Q14676	MDC1	P53350	PLK1	S1669	P1672S	1672	Missense	distal	3	no	13.172	13.151	EPSD	COSMIC	10.919	Down-regulation
Other_PLK_PLK1_PLK1_ST	Q14676	MDC1	P53350	PLK1	S1669	T1671P	1671	Missense	proximal	2	no	13.172	12.336	EPSD	COSMIC	10.919	Down-regulation
Other_PLK_PLK1_PLK1_ST	Q14676	MDC1	P53350	PLK1	S1669	P1662S	1662	Missense	distal	-7	no	13.172	13.383	EPSD	COSMIC	10.919	Up-regulation
Other_PLK_PLK1_PLK1_ST	Q14676	MDC1	P53350	PLK1	S1669	T1664S	1664	Missense	distal	-5	no	13.172	12.958	EPSD	COSMIC	10.919	Down-regulation
Other_PLK_PLK1_PLK1_ST	Q14676	MDC1	P53350	PLK1	S1669	Q1668L	1668	Missense	proximal	-1	no	13.172	13.045	EPSD	COSMIC	10.919	Down-regulation
Other_PLK_PLK1_PLK1_ST	Q14676	MDC1	P53350	PLK1	S1669	D1667E	1667	Missense	proximal	-2	no	13.172	12.779	EPSD	COSMIC	10.919	Down-regulation
Other_PLK_PLK1_PLK1_ST	Q14676	MDC1	P53350	PLK1	S1915	A1921T	1921	Missense	distal	6	no	11.282	11.275	EPSD	COSMIC	10.919	Down-regulation
Other_PLK_PLK1_PLK1_ST	Q14676	MDC1	P53350	PLK1	S1915	V1909L	1909	Missense	distal	-6	no	11.282	11.223	EPSD	COSMIC	10.919	Down-regulation
Other_PLK_PLK1_PLK1_ST	Q14676	MDC1	P53350	PLK1	S1915	E1922D	1922	Missense	distal	7	no	11.282	11.278	EPSD	COSMIC	10.919	Down-regulation
Other_PLK_PLK1_PLK1_ST	Q14676	MDC1	P53350	PLK1	S1924	A1921T	1921	Missense	distal	-3	no	12.058	11.912	EPSD	COSMIC	10.919	Down-regulation
Other_PLK_PLK1_PLK1_ST	Q14676	MDC1	P53350	PLK1	S1924	R1930S	1930	Missense	distal	6	no	12.058	12.365	EPSD	COSMIC	10.919	Up-regulation
Other_PLK_PLK1_PLK1_ST	Q14676	MDC1	P53350	PLK1	S1924	R1930G	1930	Missense	distal	6	no	12.058	12.161	EPSD	COSMIC	10.919	Up-regulation
Other_PLK_PLK1_PLK1_ST	Q14676	MDC1	P53350	PLK1	S1924	E1922D	1922	Missense	proximal	-2	no	12.058	12.452	EPSD	COSMIC	10.919	Up-regulation
Other_PLK_PLK1_PLK1_ST	P49959	MRE11	P53350	PLK1	T12	A6T	6	Missense	distal	-6	no	11.754	11.686	EPSD	COSMIC	10.919	Down-regulation
Other_PLK_PLK1_PLK1_ST	P49959	MRE11	P53350	PLK1	T12	I15L	15	Missense	distal	3	no	11.754	11.578	EPSD	COSMIC	10.919	Down-regulation
Other_PLK_PLK1_PLK1_ST	P49959	MRE11	P53350	PLK1	T12	T19A	19	Missense	distal	7	no	11.754	11.794	EPSD	COSMIC	10.919	Up-regulation
Other_PLK_PLK1_PLK1_ST	P49959	MRE11	P53350	PLK1	T12	E10Q	10	Missense	proximal	-2	no	11.754	9.095	EPSD	COSMIC	10.919	Loss
Other_PLK_PLK1_PLK1_ST	P49959	MRE11	P53350	PLK1	T12	E10G	10	Missense	proximal	-2	no	11.754	8.826	EPSD	COSMIC	10.919	Loss
Other_PLK_PLK1_PLK1_ST	P49959	MRE11	P53350	PLK1	S165	V167I	167	Missense	proximal	2	no	12.739	12.957	EPSD	COSMIC	10.919	Up-regulation
Other_PLK_PLK1_PLK1_ST	P49959	MRE11	P53350	PLK1	S165	V159L	159	Missense	distal	-6	no	12.739	12.680	EPSD	COSMIC	10.919	Down-regulation
Other_PLK_PLK1_PLK1_ST	P49959	MRE11	P53350	PLK1	S165	P166L	166	Missense	proximal	1	no	12.739	13.585	EPSD	COSMIC	10.919	Up-regulation
Other_PLK_PLK1_PLK1_ST	P49959	MRE11	P53350	PLK1	S165	L168S	168	Missense	distal	3	no	12.739	12.886	EPSD	COSMIC	10.919	Up-regulation
Other_PLK_PLK1_PLK1_ST	P49959	MRE11	P53350	PLK1	S165	G172E	172	Missense	distal	7	no	12.739	12.718	EPSD	COSMIC	10.919	Down-regulation
Other_PLK_PLK1_PLK1_ST	P49959	MRE11	P53350	PLK1	S165	D163N	163	Missense	proximal	-2	no	12.739	11.497	EPSD	COSMIC	10.919	Down-regulation
Other_PLK_PLK1_PLK1_ST	P49959	MRE11	P53350	PLK1	S183	G182R	182	Missense	proximal	-1	no	10.846	11.707	EPSD	COSMIC	10.919	Gain
Other_PLK_PLK1_PLK1_ST	P49959	MRE11	P53350	PLK1	S334	Q330K	330	Missense	distal	-4	no	12.083	11.969	EPSD	COSMIC;GDSC	10.919	Down-regulation
Other_PLK_PLK1_PLK1_ST	P49959	MRE11	P53350	PLK1	S334	I340T	340	Missense	distal	6	no	12.083	12.357	EPSD	COSMIC	10.919	Up-regulation
Other_PLK_PLK1_PLK1_ST	P49959	MRE11	P53350	PLK1	S334	I340F	340	Missense	distal	6	no	12.083	11.506	EPSD	COSMIC	10.919	Down-regulation
Other_PLK_PLK1_PLK1_ST	P49959	MRE11	P53350	PLK1	S334	Q333K	333	Missense	proximal	-1	no	12.083	11.841	EPSD	COSMIC	10.919	Down-regulation
Other_PLK_PLK1_PLK1_ST	P49959	MRE11	P53350	PLK1	S533	S531Y	531	Missense	proximal	-2	no	10.065	11.176	EPSD	COSMIC	10.919	Gain
Other_PLK_PLK1_PLK1_ST	P49959	MRE11	P53350	PLK1	S558	S563L	563	Missense	distal	5	no	11.002	10.656	EPSD	COSMIC	10.919	Loss
Other_PLK_PLK1_PLK1_ST	P49959	MRE11	P53350	PLK1	S558	S558F	558	Missense	central	0	yes	11.002	0.000	EPSD	COSMIC	10.919	Loss
Other_PLK_PLK1_PLK1_ST	P49959	MRE11	P53350	PLK1	S558	N556S	556	Missense	proximal	-2	no	11.002	9.593	EPSD	COSMIC	10.919	Loss
Other_PLK_PLK1_PLK1_ST	P49959	MRE11	P53350	PLK1	S558	A551T	551	Missense	distal	-7	no	11.002	11.347	EPSD	COSMIC;GDSC	10.919	Up-regulation
Other_PLK_PLK1_PLK1_ST	P49959	MRE11	P53350	PLK1	S558	S561F	561	Missense	distal	3	no	11.002	11.062	EPSD	COSMIC	10.919	Up-regulation
Other_PLK_PLK1_PLK1_ST	P49959	MRE11	P53350	PLK1	S561	S563L	563	Missense	proximal	2	no	12.284	12.356	EPSD	COSMIC	10.919	Up-regulation
Other_PLK_PLK1_PLK1_ST	P49959	MRE11	P53350	PLK1	S561	S558F	558	Missense	distal	-3	no	12.284	11.655	EPSD	COSMIC	10.919	Down-regulation
Other_PLK_PLK1_PLK1_ST	P49959	MRE11	P53350	PLK1	S561	N556S	556	Missense	distal	-5	no	12.284	12.337	EPSD	COSMIC	10.919	Up-regulation
Other_PLK_PLK1_PLK1_ST	P49959	MRE11	P53350	PLK1	S561	S561F	561	Missense	central	0	yes	12.284	0.000	EPSD	COSMIC	10.919	Loss
Other_PLK_PLK1_PLK1_ST	P49959	MRE11	P53350	PLK1	S619	A623V	623	Missense	distal	4	no	16.012	15.748	EPSD	COSMIC	10.919	Down-regulation
Other_PLK_PLK1_PLK1_ST	P49959	MRE11	P53350	PLK1	S619	N617H	617	Missense	proximal	-2	no	16.012	14.067	EPSD	COSMIC	10.919	Down-regulation
Other_PLK_PLK1_PLK1_ST	P49959	MRE11	P53350	PLK1	S619	D622Y	622	Missense	distal	3	no	16.012	15.586	EPSD	COSMIC	10.919	Down-regulation
Other_PLK_PLK1_PLK1_ST	P49959	MRE11	P53350	PLK1	S641	N634S	634	Missense	distal	-7	no	13.229	13.439	EPSD	COSMIC	10.919	Up-regulation
Other_PLK_PLK1_PLK1_ST	P49959	MRE11	P53350	PLK1	S649	S649L	649	Missense	central	0	yes	14.226	0.000	EPSD;PhosphoSitePlus	COSMIC	10.919	Loss
Other_PLK_PLK1_PLK1_ST	P49959	MRE11	P53350	PLK1	S649	E652K	652	Missense	distal	3	no	14.226	14.020	EPSD;PhosphoSitePlus	COSMIC	10.919	Down-regulation
Other_PLK_PLK1_PLK1_ST	P49959	MRE11	P53350	PLK1	S649	D650Y	650	Missense	proximal	1	no	14.226	14.029	EPSD;PhosphoSitePlus	COSMIC	10.919	Down-regulation
Other_PLK_PLK1_PLK1_ST	P49959	MRE11	P53350	PLK1	S676	I674N	674	Missense	proximal	-2	no	10.626	12.599	EPSD	COSMIC	10.919	Gain
Other_PLK_PLK1_PLK1_ST	P49959	MRE11	P53350	PLK1	S678	Q679K	679	Missense	proximal	1	no	10.945	10.371	EPSD	COSMIC	10.919	Loss
Other_PLK_PLK1_PLK1_ST	P49959	MRE11	P53350	PLK1	S678	G683R	683	Missense	distal	5	no	10.945	11.107	EPSD	COSMIC	10.919	Up-regulation
Other_PLK_PLK1_PLK1_ST	P49959	MRE11	P53350	PLK1	S678	I674N	674	Missense	distal	-4	no	10.945	10.777	EPSD	COSMIC	10.919	Loss
Other_PLK_PLK1_PLK1_ST	P49959	MRE11	P53350	PLK1	S678	Q679E	679	Missense	proximal	1	no	10.945	10.821	EPSD	COSMIC	10.919	Loss
Other_PLK_PLK1_PLK1_ST	P49959	MRE11	P53350	PLK1	S678	G683V	683	Missense	distal	5	no	10.945	10.591	EPSD	COSMIC	10.919	Loss
Other_PLK_PLK1_PLK1_ST	P49959	MRE11	P53350	PLK1	S678	V680I	680	Missense	proximal	2	no	10.945	11.162	EPSD	COSMIC	10.919	Up-regulation
Other_PLK_PLK1_PLK1_ST	P49959	MRE11	P53350	PLK1	S681	Q679E	679	Missense	proximal	-2	no	8.981	11.640	EPSD	COSMIC	10.919	Gain
Other_PLK_PLK1_PLK1_ST	P49959	MRE11	P53350	PLK1	S688	G683R	683	Missense	distal	-5	no	11.415	11.701	PhosphoSitePlus;EPSD	COSMIC	10.919	Up-regulation
Other_PLK_PLK1_PLK1_ST	P49959	MRE11	P53350	PLK1	S688	G683V	683	Missense	distal	-5	no	11.415	11.228	PhosphoSitePlus;EPSD	COSMIC	10.919	Down-regulation
Other_PLK_PLK1_PLK1_ST	P49959	MRE11	P53350	PLK1	S688	D695Y	695	Missense	distal	7	no	11.415	11.497	PhosphoSitePlus;EPSD	COSMIC	10.919	Up-regulation
Other_PLK_PLK1_PLK1_ST	P49959	MRE11	P53350	PLK1	S688	D694G	694	Missense	distal	6	no	11.415	10.940	PhosphoSitePlus;EPSD	COSMIC	10.919	Down-regulation
Other_PLK_PLK1_PLK1_ST	P49959	MRE11	P53350	PLK1	S688	D693G	693	Missense	distal	5	no	11.415	11.449	PhosphoSitePlus;EPSD	COSMIC	10.919	Up-regulation
Other_PLK_PLK1_PLK1_ST	P49959	MRE11	P53350	PLK1	S688	D694Y	694	Missense	distal	6	no	11.415	10.617	PhosphoSitePlus;EPSD	COSMIC	10.919	Loss
Other_PLK_PLK1_PLK1_ST	P49959	MRE11	P53350	PLK1	S689	G683R	683	Missense	distal	-6	no	13.487	13.585	EPSD	COSMIC	10.919	Up-regulation
Other_PLK_PLK1_PLK1_ST	P49959	MRE11	P53350	PLK1	S689	P696S	696	Missense	distal	7	no	13.487	13.460	EPSD	COSMIC	10.919	Down-regulation
Other_PLK_PLK1_PLK1_ST	P49959	MRE11	P53350	PLK1	S689	G683V	683	Missense	distal	-6	no	13.487	13.758	EPSD	COSMIC	10.919	Up-regulation
Other_PLK_PLK1_PLK1_ST	P49959	MRE11	P53350	PLK1	S689	D695Y	695	Missense	distal	6	no	13.487	12.688	EPSD	COSMIC	10.919	Down-regulation
Other_PLK_PLK1_PLK1_ST	P49959	MRE11	P53350	PLK1	S689	D694G	694	Missense	distal	5	no	13.487	13.520	EPSD	COSMIC	10.919	Up-regulation
Other_PLK_PLK1_PLK1_ST	P49959	MRE11	P53350	PLK1	S689	D693G	693	Missense	distal	4	no	13.487	13.398	EPSD	COSMIC	10.919	Down-regulation
Other_PLK_PLK1_PLK1_ST	P49959	MRE11	P53350	PLK1	S689	D694Y	694	Missense	distal	5	no	13.487	13.180	EPSD	COSMIC	10.919	Down-regulation
Other_PLK_PLK1_PLK1_ST	O00139	KIF2A	P53350	PLK1	S135	V142I	142	Missense	distal	7	no	11.374	11.358	EPSD	COSMIC	10.919	Down-regulation
Other_PLK_PLK1_PLK1_ST	O00139	KIF2A	P53350	PLK1	S135	S128Y	128	Missense	distal	-7	no	11.374	10.762	EPSD	COSMIC	10.919	Loss
Other_PLK_PLK1_PLK1_ST	O00139	KIF2A	P53350	PLK1	S135	P141L	141	Missense	distal	6	no	11.374	11.269	EPSD	COSMIC	10.919	Down-regulation
Other_PLK_PLK1_PLK1_ST	O00139	KIF2A	P53350	PLK1	S140	V142I	142	Missense	proximal	2	no	10.725	10.942	EPSD	COSMIC	10.919	Gain
Other_PLK_PLK1_PLK1_ST	O00139	KIF2A	P53350	PLK1	S140	P141L	141	Missense	proximal	1	no	10.725	11.571	EPSD	COSMIC	10.919	Gain
Other_PLK_PLK1_PLK1_ST	O00139	KIF2A	P53350	PLK1	S207	R211Q	211	Missense	distal	4	no	10.538	11.067	EPSD	COSMIC	10.919	Gain
Other_PLK_PLK1_PLK1_ST	O00139	KIF2A	P53350	PLK1	S328	N331S	331	Missense	distal	3	no	12.325	12.280	EPSD	COSMIC	10.919	Down-regulation
Other_PLK_PLK1_PLK1_ST	O00139	KIF2A	P53350	PLK1	S484	E490Q	490	Missense	distal	6	no	12.779	12.638	EPSD	COSMIC	10.919	Down-regulation
Other_PLK_PLK1_PLK1_ST	O00139	KIF2A	P53350	PLK1	S516	N521K	521	Missense	distal	5	no	14.156	14.479	EPSD	COSMIC	10.919	Up-regulation
Other_PLK_PLK1_PLK1_ST	O00139	KIF2A	P53350	PLK1	T554	D556N	556	Missense	proximal	2	no	12.954	13.169	PhosphoSitePlus	COSMIC	10.919	Up-regulation
Other_PLK_PLK1_PLK1_ST	O00139	KIF2A	P53350	PLK1	T554	V555A	555	Missense	proximal	1	no	12.954	11.516	PhosphoSitePlus	COSMIC	10.919	Down-regulation
Other_PLK_PLK1_PLK1_ST	O00139	KIF2A	P53350	PLK1	T554	P557T	557	Missense	distal	3	no	12.954	12.795	PhosphoSitePlus	COSMIC;CCLE	10.919	Down-regulation
Other_PLK_PLK1_PLK1_ST	O00139	KIF2A	P53350	PLK1	T554	P557L	557	Missense	distal	3	no	12.954	12.786	PhosphoSitePlus	COSMIC	10.919	Down-regulation
Other_PLK_PLK1_PLK1_ST	O00139	KIF2A	P53350	PLK1	T558	P557L	557	Missense	proximal	-1	no	10.333	11.047	EPSD	COSMIC	10.919	Gain
Other_PLK_PLK1_PLK1_ST	O00139	KIF2A	P53350	PLK1	S586	V583I	583	Missense	distal	-3	no	10.662	10.937	EPSD	COSMIC	10.919	Gain
Other_PLK_PLK1_PLK1_ST	O00139	KIF2A	P53350	PLK1	S683	K680T	680	Missense	distal	-3	no	11.587	11.592	EPSD	COSMIC	10.919	Up-regulation
Other_PLK_PLK1_PLK1_ST	O00139	KIF2A	P53350	PLK1	S683	S683C	683	Missense	central	0	yes	11.587	0.000	EPSD	COSMIC	10.919	Loss
Other_PLK_PLK1_PLK1_ST	O00139	KIF2A	P53350	PLK1	S683	R678Q	678	Missense	distal	-5	no	11.587	10.847	EPSD	COSMIC	10.919	Loss
Other_PLK_PLK1_PLK1_ST	O00139	KIF2A	P53350	PLK1	S683	R678W	678	Missense	distal	-5	no	11.587	11.354	EPSD	COSMIC;CCLE	10.919	Down-regulation
Other_PLK_PLK1_PLK1_ST	O00139	KIF2A	P53350	PLK1	S683	V681E	681	Missense	proximal	-2	no	11.587	13.805	EPSD	COSMIC	10.919	Up-regulation
Other_PLK_PLK1_PLK1_ST	O00139	KIF2A	P53350	PLK1	S683	S683Y	683	Missense	central	0	yes	11.587	0.000	EPSD	COSMIC	10.919	Loss
Other_PLK_PLK1_PLK1_ST	P30260	CDC27	P53350	PLK1	T200	P206L	206	Missense	distal	6	no	10.943	10.838	EPSD	COSMIC;GDSC;CCLE	10.919	Loss
Other_PLK_PLK1_PLK1_ST	P30260	CDC27	P53350	PLK1	T200	H195Y	195	Missense	distal	-5	no	10.943	11.160	EPSD	COSMIC;GDSC;CCLE	10.919	Up-regulation
Other_PLK_PLK1_PLK1_ST	P30260	CDC27	P53350	PLK1	T200	P206S	206	Missense	distal	6	no	10.943	10.798	EPSD	COSMIC	10.919	Loss
Other_PLK_PLK1_PLK1_ST	P30260	CDC27	P53350	PLK1	T200	V201F	201	Missense	proximal	1	no	10.943	12.423	EPSD	COSMIC	10.919	Up-regulation
Other_PLK_PLK1_PLK1_ST	P30260	CDC27	P53350	PLK1	T205	P206L	206	Missense	proximal	1	no	12.506	13.352	EPSD;PhosphoSitePlus	COSMIC;GDSC;CCLE	10.919	Up-regulation
Other_PLK_PLK1_PLK1_ST	P30260	CDC27	P53350	PLK1	T205	E211D	211	Missense	distal	6	no	12.506	12.656	EPSD;PhosphoSitePlus	COSMIC	10.919	Up-regulation
Other_PLK_PLK1_PLK1_ST	P30260	CDC27	P53350	PLK1	T205	E211G	211	Missense	distal	6	no	12.506	12.181	EPSD;PhosphoSitePlus	COSMIC	10.919	Down-regulation
Other_PLK_PLK1_PLK1_ST	P30260	CDC27	P53350	PLK1	T205	I210T	210	Missense	distal	5	no	12.506	11.604	EPSD;PhosphoSitePlus	COSMIC	10.919	Down-regulation
Other_PLK_PLK1_PLK1_ST	P30260	CDC27	P53350	PLK1	T205	P206S	206	Missense	proximal	1	no	12.506	11.385	EPSD;PhosphoSitePlus	COSMIC	10.919	Down-regulation
Other_PLK_PLK1_PLK1_ST	P30260	CDC27	P53350	PLK1	T205	V201F	201	Missense	distal	-4	no	12.506	12.288	EPSD;PhosphoSitePlus	COSMIC	10.919	Down-regulation
Other_PLK_PLK1_PLK1_ST	P30260	CDC27	P53350	PLK1	S225	S220A	220	Missense	distal	-5	no	11.754	12.038	EPSD	COSMIC	10.919	Up-regulation
Other_PLK_PLK1_PLK1_ST	P30260	CDC27	P53350	PLK1	S237	I240L	240	Missense	distal	3	no	12.206	12.030	EPSD	COSMIC	10.919	Down-regulation
Other_PLK_PLK1_PLK1_ST	P30260	CDC27	P53350	PLK1	S241	G248E	248	Missense	distal	7	no	11.820	11.799	EPSD	COSMIC	10.919	Down-regulation
Other_PLK_PLK1_PLK1_ST	P30260	CDC27	P53350	PLK1	S241	I240L	240	Missense	proximal	-1	no	11.820	11.343	EPSD	COSMIC	10.919	Down-regulation
Other_PLK_PLK1_PLK1_ST	P30260	CDC27	P53350	PLK1	S241	V245A	245	Missense	distal	4	no	11.820	12.083	EPSD	COSMIC	10.919	Up-regulation
Other_PLK_PLK1_PLK1_ST	P30260	CDC27	P53350	PLK1	S252	G250E	250	Missense	proximal	-2	no	8.177	11.105	EPSD	COSMIC	10.919	Gain
Other_PLK_PLK1_PLK1_ST	P30260	CDC27	P53350	PLK1	S320	K318E	318	Missense	proximal	-2	no	8.095	10.973	EPSD	COSMIC	10.919	Gain
Other_PLK_PLK1_PLK1_ST	P30260	CDC27	P53350	PLK1	T343	E341K	341	Missense	proximal	-2	no	11.831	8.953	EPSD	COSMIC	10.919	Loss
Other_PLK_PLK1_PLK1_ST	P30260	CDC27	P53350	PLK1	T343	S339I	339	Missense	distal	-4	no	11.831	11.864	EPSD	COSMIC	10.919	Up-regulation
Other_PLK_PLK1_PLK1_ST	P30260	CDC27	P53350	PLK1	S393	T389A	389	Missense	distal	-4	no	10.865	11.267	EPSD	COSMIC	10.919	Gain
Other_PLK_PLK1_PLK1_ST	P30260	CDC27	P53350	PLK1	S426	L432S	432	Missense	distal	6	no	12.969	12.930	EPSD;PhosphoSitePlus	COSMIC	10.919	Down-regulation
Other_PLK_PLK1_PLK1_ST	P30260	CDC27	P53350	PLK1	T430	L432S	432	Missense	proximal	2	no	13.602	13.530	EPSD;PhosphoSitePlus	COSMIC	10.919	Down-regulation
Other_PLK_PLK1_PLK1_ST	P30260	CDC27	P53350	PLK1	S435	E439K	439	Missense	distal	4	no	16.993	16.619	EPSD;PhosphoSitePlus	COSMIC	10.919	Down-regulation
Other_PLK_PLK1_PLK1_ST	P30260	CDC27	P53350	PLK1	S435	L432S	432	Missense	distal	-3	no	16.993	16.219	EPSD;PhosphoSitePlus	COSMIC	10.919	Down-regulation
Other_PLK_PLK1_PLK1_ST	P30260	CDC27	P53350	PLK1	S435	K441I	441	Missense	distal	6	no	16.993	16.942	EPSD;PhosphoSitePlus	COSMIC	10.919	Down-regulation
Other_PLK_PLK1_PLK1_ST	P30260	CDC27	P53350	PLK1	S435	I442V	442	Missense	distal	7	no	16.993	17.009	EPSD;PhosphoSitePlus	COSMIC	10.919	Up-regulation
Other_PLK_PLK1_PLK1_ST	P30260	CDC27	P53350	PLK1	S553	V554F	554	Missense	proximal	1	no	9.711	11.191	EPSD	COSMIC	10.919	Gain
Other_PLK_PLK1_PLK1_ST	P30260	CDC27	P53350	PLK1	T809	D812Y	812	Missense	distal	3	no	11.704	11.278	EPSD	COSMIC	10.919	Down-regulation
Other_PLK_PLK1_PLK1_ST	P30260	CDC27	P53350	PLK1	T809	D812N	812	Missense	distal	3	no	11.704	11.504	EPSD	COSMIC	10.919	Down-regulation
Other_PLK_PLK1_PLK1_ST	P30260	CDC27	P53350	PLK1	T809	D813Y	813	Missense	distal	4	no	11.704	11.458	EPSD	COSMIC	10.919	Down-regulation
Other_PLK_PLK1_PLK1_ST	P30260	CDC27	P53350	PLK1	T809	A811T	811	Missense	proximal	2	no	11.704	11.303	EPSD	COSMIC	10.919	Down-regulation
Other_PLK_PLK1_PLK1_ST	P30260	CDC27	P53350	PLK1	T809	A811V	811	Missense	proximal	2	no	11.704	12.147	EPSD	COSMIC	10.919	Up-regulation
Other_PLK_PLK1_PLK1_ST	P30260	CDC27	P53350	PLK1	T809	Q804H	804	Missense	distal	-5	no	11.704	11.640	EPSD	COSMIC	10.919	Down-regulation
Other_PLK_PLK1_PLK1_ST	Q6PGQ7	BORA	P53350	PLK1	S270	S270L	270	Missense	central	0	yes	11.410	0.000	EPSD	COSMIC	10.919	Loss
Other_PLK_PLK1_PLK1_ST	Q6PGQ7	BORA	P53350	PLK1	S270	T276A	276	Missense	distal	6	no	11.410	11.418	EPSD	COSMIC	10.919	Up-regulation
Other_PLK_PLK1_PLK1_ST	Q6PGQ7	BORA	P53350	PLK1	T296	S290N	290	Missense	distal	-6	no	11.293	11.096	EPSD	COSMIC	10.919	Down-regulation
Other_PLK_PLK1_PLK1_ST	Q6PGQ7	BORA	P53350	PLK1	T445	T446K	446	Missense	proximal	1	no	12.061	11.709	EPSD	COSMIC	10.919	Down-regulation
Other_PLK_PLK1_PLK1_ST	Q6PGQ7	BORA	P53350	PLK1	T446	T446K	446	Missense	central	0	yes	11.510	0.000	EPSD	COSMIC	10.919	Loss
Other_PLK_PLK1_PLK1_ST	Q96CV9	OPTN	P53350	PLK1	T20	H26D	26	Missense	distal	6	no	13.940	14.734	EPSD	COSMIC	10.919	Up-regulation
Other_PLK_PLK1_PLK1_ST	Q96CV9	OPTN	P53350	PLK1	S191	I195N	195	Missense	distal	4	no	10.194	11.149	EPSD	COSMIC	10.919	Gain
Other_PLK_PLK1_PLK1_ST	Q96CV9	OPTN	P53350	PLK1	S234	E227K	227	Missense	distal	-7	no	11.744	11.440	EPSD	COSMIC	10.919	Down-regulation
Other_PLK_PLK1_PLK1_ST	Q96CV9	OPTN	P53350	PLK1	S234	L236I	236	Missense	proximal	2	no	11.744	12.094	EPSD	COSMIC	10.919	Up-regulation
Other_PLK_PLK1_PLK1_ST	Q96CV9	OPTN	P53350	PLK1	S234	L231P	231	Missense	distal	-3	no	11.744	10.552	EPSD	COSMIC	10.919	Loss
Other_PLK_PLK1_PLK1_ST	Q96CV9	OPTN	P53350	PLK1	S272	R271H	271	Missense	proximal	-1	no	11.062	12.059	EPSD	COSMIC	10.919	Up-regulation
Other_PLK_PLK1_PLK1_ST	Q96CV9	OPTN	P53350	PLK1	S513	E507K	507	Missense	distal	-6	no	11.791	11.217	EPSD	COSMIC	10.919	Down-regulation
Other_PLK_PLK1_PLK1_ST	Q96CV9	OPTN	P53350	PLK1	S528	R524K	524	Missense	distal	-4	no	12.087	12.260	EPSD	COSMIC;GDSC;CCLE	10.919	Up-regulation
Other_PLK_PLK1_PLK1_ST	Q9HAW4	CLSPN	P53350	PLK1	S30	P27S	27	Missense	distal	-3	no	12.409	12.827	PhosphoSitePlus	COSMIC	10.919	Up-regulation
Other_PLK_PLK1_PLK1_ST	Q9HAW4	CLSPN	P53350	PLK1	S65	D66N	66	Missense	proximal	1	no	11.089	10.894	EPSD	COSMIC	10.919	Loss
Other_PLK_PLK1_PLK1_ST	Q9HAW4	CLSPN	P53350	PLK1	T72	A74V	74	Missense	proximal	2	no	11.782	12.225	EPSD	COSMIC;GDSC;CCLE	10.919	Up-regulation
Other_PLK_PLK1_PLK1_ST	Q9HAW4	CLSPN	P53350	PLK1	T72	D66N	66	Missense	distal	-6	no	11.782	11.669	EPSD	COSMIC	10.919	Down-regulation
Other_PLK_PLK1_PLK1_ST	Q9HAW4	CLSPN	P53350	PLK1	T79	A74V	74	Missense	distal	-5	no	11.539	11.467	EPSD	COSMIC;GDSC;CCLE	10.919	Down-regulation
Other_PLK_PLK1_PLK1_ST	Q9HAW4	CLSPN	P53350	PLK1	S83	E90V	90	Missense	distal	7	no	12.550	12.621	EPSD	COSMIC	10.919	Up-regulation
Other_PLK_PLK1_PLK1_ST	Q9HAW4	CLSPN	P53350	PLK1	S426	V427M	427	Missense	proximal	1	no	15.174	16.330	EPSD	COSMIC	10.919	Up-regulation
Other_PLK_PLK1_PLK1_ST	Q9HAW4	CLSPN	P53350	PLK1	S516	R509Q	509	Missense	distal	-7	no	14.014	14.414	EPSD	COSMIC	10.919	Up-regulation
Other_PLK_PLK1_PLK1_ST	Q9HAW4	CLSPN	P53350	PLK1	S704	G702D	702	Missense	proximal	-2	no	8.198	11.520	EPSD	COSMIC	10.919	Gain
Other_PLK_PLK1_PLK1_ST	Q9HAW4	CLSPN	P53350	PLK1	T724	L727R	727	Missense	distal	3	no	10.943	10.965	EPSD	COSMIC	10.919	Up-regulation
Other_PLK_PLK1_PLK1_ST	Q9HAW4	CLSPN	P53350	PLK1	S733	M735I	735	Missense	proximal	2	no	10.633	11.056	EPSD	COSMIC	10.919	Gain
Other_PLK_PLK1_PLK1_ST	Q9HAW4	CLSPN	P53350	PLK1	S762	D760G	760	Missense	proximal	-2	no	13.073	9.751	EPSD	COSMIC	10.919	Loss
Other_PLK_PLK1_PLK1_ST	Q9HAW4	CLSPN	P53350	PLK1	S762	S755F	755	Missense	distal	-7	no	13.073	12.615	EPSD	COSMIC	10.919	Down-regulation
Other_PLK_PLK1_PLK1_ST	Q9HAW4	CLSPN	P53350	PLK1	S762	E769Q	769	Missense	distal	7	no	13.073	13.126	EPSD	COSMIC	10.919	Up-regulation
Other_PLK_PLK1_PLK1_ST	Q9HAW4	CLSPN	P53350	PLK1	S762	K768M	768	Missense	distal	6	no	13.073	12.765	EPSD	COSMIC	10.919	Down-regulation
Other_PLK_PLK1_PLK1_ST	Q9HAW4	CLSPN	P53350	PLK1	S762	D760Y	760	Missense	proximal	-2	no	13.073	11.531	EPSD	COSMIC;GDSC;CCLE	10.919	Down-regulation
Other_PLK_PLK1_PLK1_ST	Q9HAW4	CLSPN	P53350	PLK1	S762	C763Y	763	Missense	proximal	1	no	13.073	13.575	EPSD	COSMIC	10.919	Up-regulation
Other_PLK_PLK1_PLK1_ST	Q9HAW4	CLSPN	P53350	PLK1	S771	E769Q	769	Missense	proximal	-2	no	13.109	10.450	EPSD	COSMIC	10.919	Loss
Other_PLK_PLK1_PLK1_ST	Q9HAW4	CLSPN	P53350	PLK1	S771	K768M	768	Missense	distal	-3	no	13.109	12.990	EPSD	COSMIC	10.919	Down-regulation
Other_PLK_PLK1_PLK1_ST	Q9HAW4	CLSPN	P53350	PLK1	S771	S770R	770	Missense	proximal	-1	no	13.109	12.172	EPSD	COSMIC	10.919	Down-regulation
Other_PLK_PLK1_PLK1_ST	Q9HAW4	CLSPN	P53350	PLK1	S775	S770R	770	Missense	distal	-5	no	10.244	10.928	EPSD	COSMIC	10.919	Gain
Other_PLK_PLK1_PLK1_ST	Q9HAW4	CLSPN	P53350	PLK1	S954	S959L	959	Missense	distal	5	no	11.723	11.376	EPSD	COSMIC	10.919	Down-regulation
Other_PLK_PLK1_PLK1_ST	Q9HAW4	CLSPN	P53350	PLK1	S954	F948I	948	Missense	distal	-6	no	11.723	12.309	EPSD	COSMIC	10.919	Up-regulation
Other_PLK_PLK1_PLK1_ST	Q9HAW4	CLSPN	P53350	PLK1	S954	D952H	952	Missense	proximal	-2	no	11.723	8.536	EPSD	COSMIC	10.919	Loss
Other_PLK_PLK1_PLK1_ST	Q9HAW4	CLSPN	P53350	PLK1	S969	K966R	966	Missense	distal	-3	no	13.432	13.893	EPSD	COSMIC	10.919	Up-regulation
Other_PLK_PLK1_PLK1_ST	Q9HAW4	CLSPN	P53350	PLK1	S969	M970I	970	Missense	proximal	1	no	13.432	12.467	EPSD	COSMIC	10.919	Down-regulation
Other_PLK_PLK1_PLK1_ST	Q9HAW4	CLSPN	P53350	PLK1	S969	S969N	969	Missense	central	0	yes	13.432	0.000	EPSD	COSMIC	10.919	Loss
Other_PLK_PLK1_PLK1_ST	Q9HAW4	CLSPN	P53350	PLK1	S1018	D1019N	1019	Missense	proximal	1	no	12.314	12.119	EPSD	COSMIC	10.919	Down-regulation
Other_PLK_PLK1_PLK1_ST	Q9HAW4	CLSPN	P53350	PLK1	S1018	L1024M	1024	Missense	distal	6	no	12.314	12.020	EPSD	COSMIC	10.919	Down-regulation
Other_PLK_PLK1_PLK1_ST	Q9HAW4	CLSPN	P53350	PLK1	S1018	D1011H	1011	Missense	distal	-7	no	12.314	12.547	EPSD	COSMIC	10.919	Up-regulation
Other_PLK_PLK1_PLK1_ST	Q9HAW4	CLSPN	P53350	PLK1	S1018	D1013Y	1013	Missense	distal	-5	no	12.314	12.168	EPSD	COSMIC	10.919	Down-regulation
Other_PLK_PLK1_PLK1_ST	Q9HAW4	CLSPN	P53350	PLK1	S1020	D1019N	1019	Missense	proximal	-1	no	11.043	10.110	EPSD	COSMIC	10.919	Loss
Other_PLK_PLK1_PLK1_ST	Q9HAW4	CLSPN	P53350	PLK1	S1020	L1024M	1024	Missense	distal	4	no	11.043	10.706	EPSD	COSMIC	10.919	Loss
Other_PLK_PLK1_PLK1_ST	Q9HAW4	CLSPN	P53350	PLK1	S1020	D1013Y	1013	Missense	distal	-7	no	11.043	10.781	EPSD	COSMIC	10.919	Loss
Other_PLK_PLK1_PLK1_ST	Q9HAW4	CLSPN	P53350	PLK1	S1147	M1149I	1149	Missense	proximal	2	no	11.081	11.504	EPSD	COSMIC	10.919	Up-regulation
Other_PLK_PLK1_PLK1_ST	Q9HAW4	CLSPN	P53350	PLK1	S1168	R1171H	1171	Missense	distal	3	no	13.045	13.177	EPSD	COSMIC	10.919	Up-regulation
Other_PLK_PLK1_PLK1_ST	Q9HAW4	CLSPN	P53350	PLK1	S1302	A1295V	1295	Missense	distal	-7	no	11.298	11.355	EPSD	COSMIC	10.919	Up-regulation
Other_PLK_PLK1_PLK1_ST	Q9HAW4	CLSPN	P53350	PLK1	S1302	P1309R	1309	Missense	distal	7	no	11.298	11.287	EPSD	COSMIC	10.919	Down-regulation
Other_PLK_PLK1_PLK1_ST	Q9HAW4	CLSPN	P53350	PLK1	S1302	E1298G	1298	Missense	distal	-4	no	11.298	10.654	EPSD	COSMIC	10.919	Loss
Other_PLK_PLK1_PLK1_ST	Q9HAW4	CLSPN	P53350	PLK1	S1310	P1315L	1315	Missense	distal	5	no	11.573	10.839	EPSD	COSMIC	10.919	Loss
Other_PLK_PLK1_PLK1_ST	Q9HAW4	CLSPN	P53350	PLK1	S1310	P1309R	1309	Missense	proximal	-1	no	11.573	11.810	EPSD	COSMIC	10.919	Up-regulation
Other_PLK_PLK1_PLK1_ST	Q9HAW4	CLSPN	P53350	PLK1	S1316	P1315L	1315	Missense	proximal	-1	no	10.945	11.659	EPSD	COSMIC	10.919	Up-regulation
Other_PLK_PLK1_PLK1_ST	Q9HAW4	CLSPN	P53350	PLK1	S1316	D1323Y	1323	Missense	distal	7	no	10.945	11.026	EPSD	COSMIC	10.919	Up-regulation
Other_PLK_PLK1_PLK1_ST	Q9HAW4	CLSPN	P53350	PLK1	S1316	P1309R	1309	Missense	distal	-7	no	10.945	10.658	EPSD	COSMIC	10.919	Loss
Other_PLK_PLK1_PLK1_ST	Q9HAW4	CLSPN	P53350	PLK1	S1325	D1323Y	1323	Missense	proximal	-2	no	13.277	11.735	EPSD	COSMIC	10.919	Down-regulation
Other_PLK_PLK1_PLK1_ST	Q9HAW4	CLSPN	P53350	PLK1	S1325	S1332N	1332	Missense	distal	7	no	13.277	13.333	EPSD	COSMIC	10.919	Up-regulation
Other_PLK_PLK1_PLK1_ST	Q9HAW4	CLSPN	P53350	PLK1	T1326	D1323Y	1323	Missense	distal	-3	no	12.128	12.307	EPSD	COSMIC	10.919	Up-regulation
Other_PLK_PLK1_PLK1_ST	Q9HAW4	CLSPN	P53350	PLK1	T1326	S1332N	1332	Missense	distal	6	no	12.128	12.179	EPSD	COSMIC	10.919	Up-regulation
Other_PLK_PLK1_PLK1_ST	Q13526	PIN1	P53350	PLK1	S138	P133L	133	Missense	distal	-5	no	12.530	12.932	EPSD	COSMIC	10.919	Up-regulation
Other_PLK_PLK1_PLK1_ST	Q13526	PIN1	P53350	PLK1	S147	P149S	149	Missense	proximal	2	no	11.576	13.052	EPSD	COSMIC	10.919	Up-regulation
Other_PLK_PLK1_PLK1_ST	Q13526	PIN1	P53350	PLK1	S147	T152M	152	Missense	distal	5	no	11.576	12.277	EPSD	COSMIC	10.919	Up-regulation
Other_PLK_PLK1_PLK1_ST	Q8NG31	KNL1	P53350	PLK1	S60	R57C	57	Missense	distal	-3	no	12.626	11.830	EPSD	COSMIC	10.919	Down-regulation
Other_PLK_PLK1_PLK1_ST	Q8NG31	KNL1	P53350	PLK1	S60	S60N	60	Missense	central	0	yes	12.626	0.000	EPSD	COSMIC	10.919	Loss
Other_PLK_PLK1_PLK1_ST	Q8NG31	KNL1	P53350	PLK1	T133	N136S	136	Missense	distal	3	no	11.824	11.779	EPSD	COSMIC	10.919	Down-regulation
Other_PLK_PLK1_PLK1_ST	Q8NG31	KNL1	P53350	PLK1	T133	L138V	138	Missense	distal	5	no	11.824	11.999	EPSD	COSMIC	10.919	Up-regulation
Other_PLK_PLK1_PLK1_ST	Q8NG31	KNL1	P53350	PLK1	T133	D127N	127	Missense	distal	-6	no	11.824	11.711	EPSD	COSMIC	10.919	Down-regulation
Other_PLK_PLK1_PLK1_ST	Q8NG31	KNL1	P53350	PLK1	T133	S140C	140	Missense	distal	7	no	11.824	11.893	EPSD	COSMIC	10.919	Up-regulation
Other_PLK_PLK1_PLK1_ST	Q8NG31	KNL1	P53350	PLK1	T133	L139I	139	Missense	distal	6	no	11.824	11.786	EPSD	COSMIC	10.919	Down-regulation
Other_PLK_PLK1_PLK1_ST	Q8NG31	KNL1	P53350	PLK1	T133	Y129H	129	Missense	distal	-4	no	11.824	12.246	EPSD	COSMIC	10.919	Up-regulation
Other_PLK_PLK1_PLK1_ST	Q8NG31	KNL1	P53350	PLK1	S153	T158A	158	Missense	distal	5	no	14.213	15.385	EPSD	COSMIC	10.919	Up-regulation
Other_PLK_PLK1_PLK1_ST	Q8NG31	KNL1	P53350	PLK1	S153	R159S	159	Missense	distal	6	no	14.213	14.520	EPSD	COSMIC	10.919	Up-regulation
Other_PLK_PLK1_PLK1_ST	Q8NG31	KNL1	P53350	PLK1	S153	E151G	151	Missense	proximal	-2	no	14.213	11.285	EPSD	COSMIC	10.919	Down-regulation
Other_PLK_PLK1_PLK1_ST	Q8NG31	KNL1	P53350	PLK1	S234	S235L	235	Missense	proximal	1	no	9.955	11.922	EPSD	COSMIC	10.919	Gain
Other_PLK_PLK1_PLK1_ST	Q8NG31	KNL1	P53350	PLK1	S402	S405F	405	Missense	distal	3	no	12.848	12.908	EPSD	COSMIC	10.919	Up-regulation
Other_PLK_PLK1_PLK1_ST	Q8NG31	KNL1	P53350	PLK1	S402	D400N	400	Missense	proximal	-2	no	12.848	11.606	EPSD	COSMIC	10.919	Down-regulation
Other_PLK_PLK1_PLK1_ST	Q8NG31	KNL1	P53350	PLK1	S441	M437T	437	Missense	distal	-4	no	12.361	12.275	EPSD	COSMIC	10.919	Down-regulation
Other_PLK_PLK1_PLK1_ST	Q8NG31	KNL1	P53350	PLK1	S441	S441F	441	Missense	central	0	yes	12.361	0.000	EPSD	COSMIC	10.919	Loss
Other_PLK_PLK1_PLK1_ST	Q8NG31	KNL1	P53350	PLK1	S441	S441Y	441	Missense	central	0	yes	12.361	0.000	EPSD	COSMIC	10.919	Loss
Other_PLK_PLK1_PLK1_ST	Q8NG31	KNL1	P53350	PLK1	S441	P446S	446	Missense	distal	5	no	12.361	11.974	EPSD	COSMIC	10.919	Down-regulation
Other_PLK_PLK1_PLK1_ST	Q8NG31	KNL1	P53350	PLK1	S447	P446S	446	Missense	proximal	-1	no	10.439	11.613	EPSD	COSMIC	10.919	Gain
Other_PLK_PLK1_PLK1_ST	Q8NG31	KNL1	P53350	PLK1	S458	F455L	455	Missense	distal	-3	no	10.326	11.729	EPSD	COSMIC;GDSC	10.919	Gain
Other_PLK_PLK1_PLK1_ST	Q8NG31	KNL1	P53350	PLK1	S497	S496P	496	Missense	proximal	-1	no	11.349	10.175	EPSD	COSMIC	10.919	Loss
Other_PLK_PLK1_PLK1_ST	Q8NG31	KNL1	P53350	PLK1	S497	T499I	499	Missense	proximal	2	no	11.349	12.411	EPSD	COSMIC	10.919	Up-regulation
Other_PLK_PLK1_PLK1_ST	Q8NG31	KNL1	P53350	PLK1	S497	M495V	495	Missense	proximal	-2	no	11.349	11.845	EPSD	COSMIC	10.919	Up-regulation
Other_PLK_PLK1_PLK1_ST	Q8NG31	KNL1	P53350	PLK1	S497	A494V	494	Missense	distal	-3	no	11.349	10.950	EPSD	COSMIC	10.919	Down-regulation
Other_PLK_PLK1_PLK1_ST	Q8NG31	KNL1	P53350	PLK1	S497	D493N	493	Missense	distal	-4	no	11.349	11.408	EPSD	COSMIC	10.919	Up-regulation
Other_PLK_PLK1_PLK1_ST	Q8NG31	KNL1	P53350	PLK1	S497	D493E	493	Missense	distal	-4	no	11.349	11.533	EPSD	COSMIC	10.919	Up-regulation
Other_PLK_PLK1_PLK1_ST	Q8NG31	KNL1	P53350	PLK1	S497	S496C	496	Missense	proximal	-1	no	11.349	9.488	EPSD	COSMIC	10.919	Loss
Other_PLK_PLK1_PLK1_ST	Q8NG31	KNL1	P53350	PLK1	T517	V518F	518	Missense	proximal	1	no	10.099	11.579	EPSD	COSMIC	10.919	Gain
Other_PLK_PLK1_PLK1_ST	Q8NG31	KNL1	P53350	PLK1	S530	S530L	530	Missense	central	0	yes	12.901	0.000	EPSD	COSMIC	10.919	Loss
Other_PLK_PLK1_PLK1_ST	Q8NG31	KNL1	P53350	PLK1	S530	F525L	525	Missense	distal	-5	no	12.901	13.826	EPSD	COSMIC	10.919	Up-regulation
Other_PLK_PLK1_PLK1_ST	Q8NG31	KNL1	P53350	PLK1	S530	I524M	524	Missense	distal	-6	no	12.901	12.714	EPSD	COSMIC	10.919	Down-regulation
Other_PLK_PLK1_PLK1_ST	Q8NG31	KNL1	P53350	PLK1	S582	S578P	578	Missense	distal	-4	no	10.927	10.805	EPSD	COSMIC	10.919	Loss
Other_PLK_PLK1_PLK1_ST	Q8NG31	KNL1	P53350	PLK1	S584	S578P	578	Missense	distal	-6	no	11.776	11.152	EPSD	COSMIC	10.919	Down-regulation
Other_PLK_PLK1_PLK1_ST	Q8NG31	KNL1	P53350	PLK1	T601	G595D	595	Missense	distal	-6	no	10.644	11.107	EPSD	COSMIC	10.919	Gain
Other_PLK_PLK1_PLK1_ST	Q8NG31	KNL1	P53350	PLK1	T601	G595A	595	Missense	distal	-6	no	10.644	11.155	EPSD	COSMIC	10.919	Gain
Other_PLK_PLK1_PLK1_ST	Q8NG31	KNL1	P53350	PLK1	S633	D636N	636	Missense	distal	3	no	11.515	11.315	EPSD	COSMIC	10.919	Down-regulation
Other_PLK_PLK1_PLK1_ST	Q8NG31	KNL1	P53350	PLK1	S633	S634F	634	Missense	proximal	1	no	11.515	14.563	EPSD	COSMIC	10.919	Up-regulation
Other_PLK_PLK1_PLK1_ST	Q8NG31	KNL1	P53350	PLK1	S633	S629C	629	Missense	distal	-4	no	11.515	10.703	EPSD	COSMIC	10.919	Loss
Other_PLK_PLK1_PLK1_ST	Q8NG31	KNL1	P53350	PLK1	S633	S629F	629	Missense	distal	-4	no	11.515	11.197	EPSD	COSMIC	10.919	Down-regulation
Other_PLK_PLK1_PLK1_ST	Q8NG31	KNL1	P53350	PLK1	S633	S629Y	629	Missense	distal	-4	no	11.515	10.828	EPSD	COSMIC	10.919	Loss
Other_PLK_PLK1_PLK1_ST	Q8NG31	KNL1	P53350	PLK1	S633	E640D	640	Missense	distal	7	no	11.515	11.511	EPSD	COSMIC	10.919	Down-regulation
Other_PLK_PLK1_PLK1_ST	Q8NG31	KNL1	P53350	PLK1	T642	D636N	636	Missense	distal	-6	no	11.040	10.927	EPSD	COSMIC	10.919	Down-regulation
Other_PLK_PLK1_PLK1_ST	Q8NG31	KNL1	P53350	PLK1	T642	E640D	640	Missense	proximal	-2	no	11.040	11.433	EPSD	COSMIC	10.919	Up-regulation
Other_PLK_PLK1_PLK1_ST	Q8NG31	KNL1	P53350	PLK1	S659	D662N	662	Missense	distal	3	no	11.403	11.203	EPSD	COSMIC	10.919	Down-regulation
Other_PLK_PLK1_PLK1_ST	Q8NG31	KNL1	P53350	PLK1	S659	T661S	661	Missense	proximal	2	no	11.403	12.044	EPSD	COSMIC	10.919	Up-regulation
Other_PLK_PLK1_PLK1_ST	Q8NG31	KNL1	P53350	PLK1	S682	P683L	683	Missense	proximal	1	no	10.135	10.981	EPSD	COSMIC	10.919	Gain
Other_PLK_PLK1_PLK1_ST	Q8NG31	KNL1	P53350	PLK1	S735	S730L	730	Missense	distal	-5	no	10.576	11.240	EPSD	COSMIC	10.919	Gain
Other_PLK_PLK1_PLK1_ST	Q8NG31	KNL1	P53350	PLK1	S765	P761T	761	Missense	distal	-4	no	12.073	11.832	EPSD	COSMIC	10.919	Down-regulation
Other_PLK_PLK1_PLK1_ST	Q8NG31	KNL1	P53350	PLK1	S858	K863T	863	Missense	distal	5	no	11.539	11.215	EPSD	COSMIC	10.919	Down-regulation
Other_PLK_PLK1_PLK1_ST	Q8NG31	KNL1	P53350	PLK1	S858	P865L	865	Missense	distal	7	no	11.539	11.510	EPSD	COSMIC;GDSC	10.919	Down-regulation
Other_PLK_PLK1_PLK1_ST	Q8NG31	KNL1	P53350	PLK1	S858	P865S	865	Missense	distal	7	no	11.539	11.512	EPSD	COSMIC;GDSC	10.919	Down-regulation
Other_PLK_PLK1_PLK1_ST	Q8NG31	KNL1	P53350	PLK1	S891	D897N	897	Missense	distal	6	no	11.345	11.124	EPSD	COSMIC	10.919	Down-regulation
Other_PLK_PLK1_PLK1_ST	Q8NG31	KNL1	P53350	PLK1	S891	M898T	898	Missense	distal	7	no	11.345	11.261	EPSD	COSMIC	10.919	Down-regulation
Other_PLK_PLK1_PLK1_ST	Q8NG31	KNL1	P53350	PLK1	S891	D894N	894	Missense	distal	3	no	11.345	11.145	EPSD	COSMIC	10.919	Down-regulation
Other_PLK_PLK1_PLK1_ST	Q8NG31	KNL1	P53350	PLK1	T901	D897N	897	Missense	distal	-4	no	11.145	11.204	EPSD	COSMIC	10.919	Up-regulation
Other_PLK_PLK1_PLK1_ST	Q8NG31	KNL1	P53350	PLK1	T901	E907Q	907	Missense	distal	6	no	11.145	11.005	EPSD	COSMIC	10.919	Down-regulation
Other_PLK_PLK1_PLK1_ST	Q8NG31	KNL1	P53350	PLK1	T901	M898T	898	Missense	distal	-3	no	11.145	11.270	EPSD	COSMIC	10.919	Up-regulation
Other_PLK_PLK1_PLK1_ST	Q8NG31	KNL1	P53350	PLK1	T901	D894N	894	Missense	distal	-7	no	11.145	11.285	EPSD	COSMIC	10.919	Up-regulation
Other_PLK_PLK1_PLK1_ST	Q8NG31	KNL1	P53350	PLK1	T943	R944G	944	Missense	proximal	1	no	9.992	12.094	EPSD	COSMIC	10.919	Gain
Other_PLK_PLK1_PLK1_ST	Q8NG31	KNL1	P53350	PLK1	S1063	S1063A	1063	Missense	central	0	yes	11.195	0.000	EPSD	COSMIC	10.919	Loss
Other_PLK_PLK1_PLK1_ST	Q8NG31	KNL1	P53350	PLK1	S1063	A1057V	1057	Missense	distal	-6	no	11.195	10.956	EPSD	COSMIC	10.919	Down-regulation
Other_PLK_PLK1_PLK1_ST	Q8NG31	KNL1	P53350	PLK1	S1063	M1060T	1060	Missense	distal	-3	no	11.195	11.320	EPSD	COSMIC	10.919	Up-regulation
Other_PLK_PLK1_PLK1_ST	Q8NG31	KNL1	P53350	PLK1	S1126	E1121G	1121	Missense	distal	-5	no	10.479	10.975	EPSD	COSMIC	10.919	Gain
Other_PLK_PLK1_PLK1_ST	Q8NG31	KNL1	P53350	PLK1	S1232	P1228H	1228	Missense	distal	-4	no	15.755	15.612	EPSD	COSMIC	10.919	Down-regulation
Other_PLK_PLK1_PLK1_ST	Q8NG31	KNL1	P53350	PLK1	S1232	P1228S	1228	Missense	distal	-4	no	15.755	15.877	EPSD	COSMIC	10.919	Up-regulation
Other_PLK_PLK1_PLK1_ST	Q8NG31	KNL1	P53350	PLK1	S1232	S1226F	1226	Missense	distal	-6	no	15.755	15.238	EPSD	COSMIC	10.919	Down-regulation
Other_PLK_PLK1_PLK1_ST	Q8NG31	KNL1	P53350	PLK1	S1232	C1233G	1233	Missense	proximal	1	no	15.755	16.457	EPSD	COSMIC	10.919	Up-regulation
Other_PLK_PLK1_PLK1_ST	Q8NG31	KNL1	P53350	PLK1	T1266	R1265I	1265	Missense	proximal	-1	no	11.126	12.079	EPSD	COSMIC;GDSC	10.919	Up-regulation
Other_PLK_PLK1_PLK1_ST	Q8NG31	KNL1	P53350	PLK1	T1266	F1260L	1260	Missense	distal	-6	no	11.126	11.309	EPSD	COSMIC	10.919	Up-regulation
Other_PLK_PLK1_PLK1_ST	Q8NG31	KNL1	P53350	PLK1	T1266	N1264K	1264	Missense	proximal	-2	no	11.126	9.097	EPSD	COSMIC	10.919	Loss
Other_PLK_PLK1_PLK1_ST	Q8NG31	KNL1	P53350	PLK1	T1429	L1436V	1436	Missense	distal	7	no	13.119	13.169	EPSD	COSMIC	10.919	Up-regulation
Other_PLK_PLK1_PLK1_ST	Q8NG31	KNL1	P53350	PLK1	T1429	R1422Q	1422	Missense	distal	-7	no	13.119	13.519	EPSD	COSMIC	10.919	Up-regulation
Other_PLK_PLK1_PLK1_ST	Q8NG31	KNL1	P53350	PLK1	T1429	N1423K	1423	Missense	distal	-6	no	13.119	12.861	EPSD	COSMIC;GDSC	10.919	Down-regulation
Other_PLK_PLK1_PLK1_ST	Q8NG31	KNL1	P53350	PLK1	S1433	M1439T	1439	Missense	distal	6	no	10.591	11.122	EPSD	COSMIC	10.919	Gain
Other_PLK_PLK1_PLK1_ST	Q8NG31	KNL1	P53350	PLK1	T1440	M1439T	1439	Missense	proximal	-1	no	11.231	10.412	EPSD	COSMIC	10.919	Loss
Other_PLK_PLK1_PLK1_ST	Q8NG31	KNL1	P53350	PLK1	T1440	S1444L	1444	Missense	distal	4	no	11.231	10.618	EPSD	COSMIC	10.919	Loss
Other_PLK_PLK1_PLK1_ST	Q8NG31	KNL1	P53350	PLK1	T1440	L1436V	1436	Missense	distal	-4	no	11.231	11.324	EPSD	COSMIC	10.919	Up-regulation
Other_PLK_PLK1_PLK1_ST	Q8NG31	KNL1	P53350	PLK1	S1660	P1662L	1662	Missense	proximal	2	no	9.582	11.130	EPSD	COSMIC	10.919	Gain
Other_PLK_PLK1_PLK1_ST	Q8NG31	KNL1	P53350	PLK1	S1690	C1689Y	1689	Missense	proximal	-1	no	9.905	12.101	EPSD	COSMIC	10.919	Gain
Other_PLK_PLK1_PLK1_ST	Q8NG31	KNL1	P53350	PLK1	T1705	E1698K	1698	Missense	distal	-7	no	14.107	13.803	EPSD	COSMIC	10.919	Down-regulation
Other_PLK_PLK1_PLK1_ST	Q8NG31	KNL1	P53350	PLK1	T1705	L1710V	1710	Missense	distal	5	no	14.107	14.282	EPSD	COSMIC	10.919	Up-regulation
Other_PLK_PLK1_PLK1_ST	Q8NG31	KNL1	P53350	PLK1	T1705	D1706N	1706	Missense	proximal	1	no	14.107	13.913	EPSD	COSMIC	10.919	Down-regulation
Other_PLK_PLK1_PLK1_ST	Q8NG31	KNL1	P53350	PLK1	S1720	S1716C	1716	Missense	distal	-4	no	12.340	11.528	EPSD	COSMIC	10.919	Down-regulation
Other_PLK_PLK1_PLK1_ST	Q8NG31	KNL1	P53350	PLK1	S1720	S1717I	1717	Missense	distal	-3	no	12.340	12.739	EPSD	COSMIC	10.919	Up-regulation
Other_PLK_PLK1_PLK1_ST	Q8NG31	KNL1	P53350	PLK1	S1720	S1717R	1717	Missense	distal	-3	no	12.340	13.172	EPSD	COSMIC	10.919	Up-regulation
Other_PLK_PLK1_PLK1_ST	Q8NG31	KNL1	P53350	PLK1	S1732	P1733L	1733	Missense	proximal	1	no	12.467	13.312	EPSD	COSMIC	10.919	Up-regulation
Other_PLK_PLK1_PLK1_ST	Q8NG31	KNL1	P53350	PLK1	S1732	N1730K	1730	Missense	proximal	-2	no	12.467	10.438	EPSD	COSMIC	10.919	Loss
Other_PLK_PLK1_PLK1_ST	Q8NG31	KNL1	P53350	PLK1	S1732	E1739K	1739	Missense	distal	7	no	12.467	12.540	EPSD	COSMIC	10.919	Up-regulation
Other_PLK_PLK1_PLK1_ST	Q8NG31	KNL1	P53350	PLK1	S1752	S1751Y	1751	Missense	proximal	-1	no	10.854	11.190	EPSD	COSMIC	10.919	Gain
Other_PLK_PLK1_PLK1_ST	Q8NG31	KNL1	P53350	PLK1	S1754	S1751Y	1751	Missense	distal	-3	no	14.020	14.489	EPSD	COSMIC	10.919	Up-regulation
Other_PLK_PLK1_PLK1_ST	Q8NG31	KNL1	P53350	PLK1	S1754	E1748A	1748	Missense	distal	-6	no	14.020	13.866	EPSD	COSMIC	10.919	Down-regulation
Other_PLK_PLK1_PLK1_ST	Q8NG31	KNL1	P53350	PLK1	S1754	E1761G	1761	Missense	distal	7	no	14.020	14.042	EPSD	COSMIC	10.919	Up-regulation
Other_PLK_PLK1_PLK1_ST	Q8NG31	KNL1	P53350	PLK1	S1754	S1751F	1751	Missense	distal	-3	no	14.020	13.391	EPSD	COSMIC	10.919	Down-regulation
Other_PLK_PLK1_PLK1_ST	Q8NG31	KNL1	P53350	PLK1	S1773	E1771Q	1771	Missense	proximal	-2	no	11.093	8.434	EPSD	COSMIC	10.919	Loss
Other_PLK_PLK1_PLK1_ST	Q8NG31	KNL1	P53350	PLK1	T1814	T1813M	1813	Missense	proximal	-1	no	10.493	11.312	EPSD	COSMIC;GDSC	10.919	Gain
Other_PLK_PLK1_PLK1_ST	Q8NG31	KNL1	P53350	PLK1	S1831	L1836F	1836	Missense	distal	5	no	11.917	12.357	EPSD	COSMIC	10.919	Up-regulation
Other_PLK_PLK1_PLK1_ST	Q8NG31	KNL1	P53350	PLK1	S1831	E1826D	1826	Missense	distal	-5	no	11.917	12.258	EPSD	COSMIC	10.919	Up-regulation
Other_PLK_PLK1_PLK1_ST	Q8NG31	KNL1	P53350	PLK1	S1831	V1835A	1835	Missense	distal	4	no	11.917	12.180	EPSD	COSMIC	10.919	Up-regulation
Other_PLK_PLK1_PLK1_ST	Q8NG31	KNL1	P53350	PLK1	S1831	D1827G	1827	Missense	distal	-4	no	11.917	11.457	EPSD	COSMIC	10.919	Down-regulation
Other_PLK_PLK1_PLK1_ST	Q8NG31	KNL1	P53350	PLK1	S1850	I1854V	1854	Missense	distal	4	no	12.277	13.006	EPSD	COSMIC	10.919	Up-regulation
Other_PLK_PLK1_PLK1_ST	Q8NG31	KNL1	P53350	PLK1	S1850	D1852Y	1852	Missense	proximal	2	no	12.277	11.910	EPSD	COSMIC	10.919	Down-regulation
Other_PLK_PLK1_PLK1_ST	Q8NG31	KNL1	P53350	PLK1	S1850	P1844Q	1844	Missense	distal	-6	no	12.277	12.900	EPSD	COSMIC	10.919	Up-regulation
Other_PLK_PLK1_PLK1_ST	Q8NG31	KNL1	P53350	PLK1	S1850	P1844S	1844	Missense	distal	-6	no	12.277	12.900	EPSD	COSMIC	10.919	Up-regulation
Other_PLK_PLK1_PLK1_ST	Q8NG31	KNL1	P53350	PLK1	S1864	R1867H	1867	Missense	distal	3	no	12.317	12.448	EPSD	COSMIC	10.919	Up-regulation
Other_PLK_PLK1_PLK1_ST	Q8NG31	KNL1	P53350	PLK1	T1879	L1885F	1885	Missense	distal	6	no	11.981	11.366	EPSD	COSMIC	10.919	Down-regulation
Other_PLK_PLK1_PLK1_ST	Q8NG31	KNL1	P53350	PLK1	T1879	D1878Y	1878	Missense	proximal	-1	no	11.981	11.525	EPSD	COSMIC	10.919	Down-regulation
Other_PLK_PLK1_PLK1_ST	Q8NG31	KNL1	P53350	PLK1	T1879	E1883D	1883	Missense	distal	4	no	11.981	11.996	EPSD	COSMIC	10.919	Up-regulation
Other_PLK_PLK1_PLK1_ST	Q8NG31	KNL1	P53350	PLK1	T1879	I1880V	1880	Missense	proximal	1	no	11.981	11.790	EPSD	COSMIC	10.919	Down-regulation
Other_PLK_PLK1_PLK1_ST	Q8NG31	KNL1	P53350	PLK1	S1986	C1985Y	1985	Missense	proximal	-1	no	8.909	11.105	EPSD	COSMIC	10.919	Gain
Other_PLK_PLK1_PLK1_ST	Q14674	ESPL1	P53350	PLK1	S810	S816C	816	Missense	distal	6	no	14.086	13.154	EPSD	COSMIC	10.919	Down-regulation
Other_PLK_PLK1_PLK1_ST	Q14674	ESPL1	P53350	PLK1	S810	G814C	814	Missense	distal	4	no	14.086	13.645	EPSD	COSMIC	10.919	Down-regulation
Other_PLK_PLK1_PLK1_ST	Q14674	ESPL1	P53350	PLK1	T1111	T1111A	1111	Missense	central	0	yes	11.985	0.000	EPSD	COSMIC	10.919	Loss
Other_PLK_PLK1_PLK1_ST	Q14674	ESPL1	P53350	PLK1	T1111	A1113V	1113	Missense	proximal	2	no	11.985	12.428	EPSD	COSMIC	10.919	Up-regulation
Other_PLK_PLK1_PLK1_ST	Q14674	ESPL1	P53350	PLK1	S1513	P1520L	1520	Missense	distal	7	no	12.865	12.836	EPSD	COSMIC	10.919	Down-regulation
Other_PLK_PLK1_PLK1_ST	Q14674	ESPL1	P53350	PLK1	T1519	P1520L	1520	Missense	proximal	1	no	11.626	12.472	EPSD	COSMIC	10.919	Up-regulation
Other_PLK_PLK1_PLK1_ST	Q14674	ESPL1	P53350	PLK1	T1519	A1521T	1521	Missense	proximal	2	no	11.626	11.225	EPSD	COSMIC	10.919	Down-regulation
Other_PLK_PLK1_PLK1_ST	Q14674	ESPL1	P53350	PLK1	S1539	K1540E	1540	Missense	proximal	1	no	10.998	11.448	EPSD	COSMIC	10.919	Up-regulation
Other_PLK_PLK1_PLK1_ST	Q9UKT4	FBXO5	P53350	PLK1	S145	E143V	143	Missense	proximal	-2	no	13.226	11.007	EPSD;PhosphoSitePlus	COSMIC	10.919	Down-regulation
Other_PLK_PLK1_PLK1_ST	Q9UKT4	FBXO5	P53350	PLK1	S145	L141F	141	Missense	distal	-4	no	13.226	13.101	EPSD;PhosphoSitePlus	COSMIC	10.919	Down-regulation
Other_PLK_PLK1_PLK1_ST	Q9UKT4	FBXO5	P53350	PLK1	S145	D144H	144	Missense	proximal	-1	no	13.226	12.494	EPSD;PhosphoSitePlus	COSMIC	10.919	Down-regulation
Other_PLK_PLK1_PLK1_ST	Q9UKT4	FBXO5	P53350	PLK1	S149	E143V	143	Missense	distal	-6	no	14.551	14.157	PhosphoSitePlus;EPSD	COSMIC	10.919	Down-regulation
Other_PLK_PLK1_PLK1_ST	Q9UKT4	FBXO5	P53350	PLK1	S149	D144H	144	Missense	distal	-5	no	14.551	14.188	PhosphoSitePlus;EPSD	COSMIC	10.919	Down-regulation
Other_PLK_PLK1_PLK1_ST	Q9UJX3	ANAPC7	P53350	PLK1	S557	S557N	557	Missense	central	0	yes	12.170	0.000	EPSD	COSMIC	10.919	Loss
Other_PLK_PLK1_PLK1_ST	Q9UJX3	ANAPC7	P53350	PLK1	S557	E555K	555	Missense	proximal	-2	no	12.170	9.293	EPSD	COSMIC	10.919	Loss
Other_PLK_PLK1_PLK1_ST	P47736	RAP1GAP	P53350	PLK1	S441	R438H	438	Missense	distal	-3	no	14.182	13.510	EPSD	COSMIC	10.919	Down-regulation
Other_PLK_PLK1_PLK1_ST	P47736	RAP1GAP	P53350	PLK1	S441	S437N	437	Missense	distal	-4	no	14.182	14.047	EPSD	COSMIC	10.919	Down-regulation
Other_PLK_PLK1_PLK1_ST	P47736	RAP1GAP	P53350	PLK1	S477	G482R	482	Missense	distal	5	no	11.280	11.442	EPSD	COSMIC	10.919	Up-regulation
Other_PLK_PLK1_PLK1_ST	P47736	RAP1GAP	P53350	PLK1	S499	A500T	500	Missense	proximal	1	no	10.619	11.081	EPSD	COSMIC	10.919	Gain
Other_PLK_PLK1_PLK1_ST	P47736	RAP1GAP	P53350	PLK1	S499	I503F	503	Missense	distal	4	no	10.619	10.996	EPSD	COSMIC	10.919	Gain
Other_PLK_PLK1_PLK1_ST	P47736	RAP1GAP	P53350	PLK1	S499	I503T	503	Missense	distal	4	no	10.619	11.618	EPSD	COSMIC	10.919	Gain
Other_PLK_PLK1_PLK1_ST	P47736	RAP1GAP	P53350	PLK1	T522	P523L	523	Missense	proximal	1	no	10.414	11.260	EPSD	COSMIC	10.919	Gain
Other_PLK_PLK1_PLK1_ST	P47736	RAP1GAP	P53350	PLK1	S525	G526W	526	Missense	proximal	1	no	10.758	11.360	PhosphoSitePlus	COSMIC	10.919	Gain
Other_PLK_PLK1_PLK1_ST	P47736	RAP1GAP	P53350	PLK1	S525	G526V	526	Missense	proximal	1	no	10.758	11.389	PhosphoSitePlus	COSMIC	10.919	Gain
Other_PLK_PLK1_PLK1_ST	P47736	RAP1GAP	P53350	PLK1	S537	P532H	532	Missense	distal	-5	no	12.170	11.789	EPSD	COSMIC	10.919	Down-regulation
Other_PLK_PLK1_PLK1_ST	P47736	RAP1GAP	P53350	PLK1	S537	Q540H	540	Missense	distal	3	no	12.170	12.106	EPSD	COSMIC	10.919	Down-regulation
Other_PLK_PLK1_PLK1_ST	P47736	RAP1GAP	P53350	PLK1	S537	S542Y	542	Missense	distal	5	no	12.170	12.013	EPSD	COSMIC	10.919	Down-regulation
Other_PLK_PLK1_PLK1_ST	P47736	RAP1GAP	P53350	PLK1	S537	S534L	534	Missense	distal	-3	no	12.170	12.944	EPSD	COSMIC	10.919	Up-regulation
Other_PLK_PLK1_PLK1_ST	P47736	RAP1GAP	P53350	PLK1	S537	S542F	542	Missense	distal	5	no	12.170	12.264	EPSD	COSMIC	10.919	Up-regulation
Other_PLK_PLK1_PLK1_ST	P47736	RAP1GAP	P53350	PLK1	S537	Q540E	540	Missense	distal	3	no	12.170	12.278	EPSD	COSMIC	10.919	Up-regulation
Other_PLK_PLK1_PLK1_ST	P47736	RAP1GAP	P53350	PLK1	S537	P543L	543	Missense	distal	6	no	12.170	12.066	EPSD	COSMIC	10.919	Down-regulation
Other_PLK_PLK1_PLK1_ST	P47736	RAP1GAP	P53350	PLK1	S538	P532H	532	Missense	distal	-6	no	11.098	11.733	EPSD	COSMIC	10.919	Up-regulation
Other_PLK_PLK1_PLK1_ST	P47736	RAP1GAP	P53350	PLK1	S538	Q540H	540	Missense	proximal	2	no	11.098	11.475	EPSD	COSMIC	10.919	Up-regulation
Other_PLK_PLK1_PLK1_ST	P47736	RAP1GAP	P53350	PLK1	S538	S542Y	542	Missense	distal	4	no	11.098	10.855	EPSD	COSMIC	10.919	Loss
Other_PLK_PLK1_PLK1_ST	P47736	RAP1GAP	P53350	PLK1	S538	S534L	534	Missense	distal	-4	no	11.098	10.904	EPSD	COSMIC	10.919	Loss
Other_PLK_PLK1_PLK1_ST	P47736	RAP1GAP	P53350	PLK1	S538	S542F	542	Missense	distal	4	no	11.098	10.284	EPSD	COSMIC	10.919	Loss
Other_PLK_PLK1_PLK1_ST	P47736	RAP1GAP	P53350	PLK1	S538	Q540E	540	Missense	proximal	2	no	11.098	10.909	EPSD	COSMIC	10.919	Loss
Other_PLK_PLK1_PLK1_ST	P47736	RAP1GAP	P53350	PLK1	S538	P543L	543	Missense	distal	5	no	11.098	10.364	EPSD	COSMIC	10.919	Loss
Other_PLK_PLK1_PLK1_ST	P47736	RAP1GAP	P53350	PLK1	S606	Y609C	609	Missense	distal	3	no	12.217	12.333	EPSD	COSMIC;GDSC	10.919	Up-regulation
Other_PLK_PLK1_PLK1_ST	P47736	RAP1GAP	P53350	PLK1	S606	W612R	612	Missense	distal	6	no	12.217	12.196	EPSD	COSMIC	10.919	Down-regulation
Other_PLK_PLK1_PLK1_ST	P47736	RAP1GAP	P53350	PLK1	S606	S606C	606	Missense	central	0	yes	12.217	0.000	EPSD	COSMIC	10.919	Loss
Other_PLK_PLK1_PLK1_ST	P47736	RAP1GAP	P53350	PLK1	S606	T611A	611	Missense	distal	5	no	12.217	13.388	EPSD	COSMIC	10.919	Up-regulation
Other_PLK_PLK1_PLK1_ST	P47736	RAP1GAP	P53350	PLK1	S606	T611M	611	Missense	distal	5	no	12.217	12.918	EPSD	COSMIC;GDSC	10.919	Up-regulation
Other_PLK_PLK1_PLK1_ST	P47736	RAP1GAP	P53350	PLK1	S606	T611K	611	Missense	distal	5	no	12.217	12.541	EPSD	COSMIC	10.919	Up-regulation
Other_PLK_PLK1_PLK1_ST	P47736	RAP1GAP	P53350	PLK1	S606	S606Y	606	Missense	central	0	yes	12.217	0.000	EPSD	COSMIC	10.919	Loss
Other_PLK_PLK1_PLK1_ST	P47736	RAP1GAP	P53350	PLK1	S610	T611M	611	Missense	proximal	1	no	8.792	10.924	EPSD	COSMIC;GDSC	10.919	Gain
Other_PLK_PLK1_PLK1_ST	P47736	RAP1GAP	P53350	PLK1	T611	Y609C	609	Missense	proximal	-2	no	11.920	8.410	EPSD	COSMIC;GDSC	10.919	Loss
Other_PLK_PLK1_PLK1_ST	P47736	RAP1GAP	P53350	PLK1	T611	W612R	612	Missense	proximal	1	no	11.920	9.217	EPSD	COSMIC	10.919	Loss
Other_PLK_PLK1_PLK1_ST	P47736	RAP1GAP	P53350	PLK1	T611	S606C	606	Missense	distal	-5	no	11.920	11.938	EPSD	COSMIC	10.919	Up-regulation
Other_PLK_PLK1_PLK1_ST	P47736	RAP1GAP	P53350	PLK1	T611	T611A	611	Missense	central	0	yes	11.920	0.000	EPSD	COSMIC	10.919	Loss
Other_PLK_PLK1_PLK1_ST	P47736	RAP1GAP	P53350	PLK1	T611	S616G	616	Missense	distal	5	no	11.920	12.103	EPSD	COSMIC	10.919	Up-regulation
Other_PLK_PLK1_PLK1_ST	P47736	RAP1GAP	P53350	PLK1	T611	T611M	611	Missense	central	0	yes	11.920	0.000	EPSD	COSMIC;GDSC	10.919	Loss
Other_PLK_PLK1_PLK1_ST	P47736	RAP1GAP	P53350	PLK1	T611	E614G	614	Missense	distal	3	no	11.920	11.743	EPSD	COSMIC	10.919	Down-regulation
Other_PLK_PLK1_PLK1_ST	P47736	RAP1GAP	P53350	PLK1	T611	T611K	611	Missense	central	0	yes	11.920	0.000	EPSD	COSMIC	10.919	Loss
Other_PLK_PLK1_PLK1_ST	P47736	RAP1GAP	P53350	PLK1	T611	S606Y	606	Missense	distal	-5	no	11.920	12.018	EPSD	COSMIC	10.919	Up-regulation
Other_PLK_PLK1_PLK1_ST	Q15208	STK38	P53350	PLK1	T183	D182N	182	Missense	proximal	-1	no	15.438	14.504	EPSD;PhosphoSitePlus	COSMIC	10.919	Down-regulation
Other_PLK_PLK1_PLK1_ST	Q15208	STK38	P53350	PLK1	S252	F257V	257	Missense	distal	5	no	12.466	12.201	EPSD	COSMIC	10.919	Down-regulation
Other_PLK_PLK1_PLK1_ST	Q15208	STK38	P53350	PLK1	S252	P254H	254	Missense	proximal	2	no	12.466	13.918	EPSD	COSMIC	10.919	Up-regulation
Other_PLK_PLK1_PLK1_ST	Q15208	STK38	P53350	PLK1	S252	S255G	255	Missense	distal	3	no	12.466	12.469	EPSD	COSMIC	10.919	Up-regulation
Other_PLK_PLK1_PLK1_ST	Q15208	STK38	P53350	PLK1	T258	F257V	257	Missense	proximal	-1	no	11.535	11.117	EPSD	COSMIC	10.919	Down-regulation
Other_PLK_PLK1_PLK1_ST	Q15208	STK38	P53350	PLK1	T258	P254H	254	Missense	distal	-4	no	11.535	11.392	EPSD	COSMIC	10.919	Down-regulation
Other_PLK_PLK1_PLK1_ST	Q15208	STK38	P53350	PLK1	T258	S255G	255	Missense	distal	-3	no	11.535	12.308	EPSD	COSMIC	10.919	Up-regulation
Other_PLK_PLK1_PLK1_ST	O75170	PPP6R2	P53350	PLK1	T261	C264F	264	Missense	distal	3	no	11.267	11.391	EPSD	COSMIC	10.919	Up-regulation
Other_PLK_PLK1_PLK1_ST	O75170	PPP6R2	P53350	PLK1	S263	C264F	264	Missense	proximal	1	no	9.553	12.366	EPSD	COSMIC	10.919	Gain
Other_PLK_PLK1_PLK1_ST	O75170	PPP6R2	P53350	PLK1	S289	R296M	296	Missense	distal	7	no	12.308	12.360	EPSD;PhosphoSitePlus	COSMIC	10.919	Up-regulation
Other_PLK_PLK1_PLK1_ST	O75170	PPP6R2	P53350	PLK1	S297	R296M	296	Missense	proximal	-1	no	11.628	12.636	EPSD	COSMIC	10.919	Up-regulation
Other_PLK_PLK1_PLK1_ST	O75170	PPP6R2	P53350	PLK1	S297	V304I	304	Missense	distal	7	no	11.628	11.612	EPSD	COSMIC	10.919	Down-regulation
Other_PLK_PLK1_PLK1_ST	O75170	PPP6R2	P53350	PLK1	S297	A299T	299	Missense	proximal	2	no	11.628	11.227	EPSD	COSMIC;GDSC;CCLE	10.919	Down-regulation
Other_PLK_PLK1_PLK1_ST	O75170	PPP6R2	P53350	PLK1	S427	P420L	420	Missense	distal	-7	no	11.505	11.411	EPSD	COSMIC	10.919	Down-regulation
Other_PLK_PLK1_PLK1_ST	O75170	PPP6R2	P53350	PLK1	S427	P431L	431	Missense	distal	4	no	11.505	11.214	EPSD	COSMIC	10.919	Down-regulation
Other_PLK_PLK1_PLK1_ST	O75170	PPP6R2	P53350	PLK1	S723	T724M	724	Missense	proximal	1	no	8.972	11.104	EPSD	COSMIC	10.919	Gain
Other_PLK_PLK1_PLK1_ST	O75170	PPP6R2	P53350	PLK1	S744	P746L	746	Missense	proximal	2	no	9.426	10.974	EPSD	COSMIC	10.919	Gain
Other_PLK_PLK1_PLK1_ST	O75170	PPP6R2	P53350	PLK1	S783	R784Q	784	Missense	proximal	1	no	9.613	11.592	EPSD	COSMIC	10.919	Gain
Other_PLK_PLK1_PLK1_ST	O75170	PPP6R2	P53350	PLK1	S783	R784W	784	Missense	proximal	1	no	9.613	12.317	EPSD	COSMIC	10.919	Gain
Other_PLK_PLK1_PLK1_ST	O75170	PPP6R2	P53350	PLK1	S822	S825F	825	Missense	distal	3	no	11.006	11.065	EPSD	COSMIC;CCLE	10.919	Up-regulation
Other_PLK_PLK1_PLK1_ST	O75170	PPP6R2	P53350	PLK1	S822	G827D	827	Missense	distal	5	no	11.006	10.972	EPSD	COSMIC	10.919	Down-regulation
Other_PLK_PLK1_PLK1_ST	O75170	PPP6R2	P53350	PLK1	S822	H829Y	829	Missense	distal	7	no	11.006	11.075	EPSD	COSMIC	10.919	Up-regulation
Other_PLK_PLK1_PLK1_ST	O75170	PPP6R2	P53350	PLK1	S822	S825C	825	Missense	distal	3	no	11.006	10.941	EPSD	COSMIC	10.919	Down-regulation
Other_PLK_PLK1_PLK1_ST	O75170	PPP6R2	P53350	PLK1	S823	S825F	825	Missense	proximal	2	no	11.551	11.000	EPSD	COSMIC;CCLE	10.919	Down-regulation
Other_PLK_PLK1_PLK1_ST	O75170	PPP6R2	P53350	PLK1	S823	G827D	827	Missense	distal	4	no	11.551	11.640	EPSD	COSMIC	10.919	Up-regulation
Other_PLK_PLK1_PLK1_ST	O75170	PPP6R2	P53350	PLK1	S823	H829Y	829	Missense	distal	6	no	11.551	11.547	EPSD	COSMIC	10.919	Down-regulation
Other_PLK_PLK1_PLK1_ST	O75170	PPP6R2	P53350	PLK1	S823	S825C	825	Missense	proximal	2	no	11.551	10.579	EPSD	COSMIC	10.919	Loss
Other_PLK_PLK1_PLK1_ST	O75170	PPP6R2	P53350	PLK1	S828	G827D	827	Missense	proximal	-1	no	8.594	11.184	EPSD	COSMIC	10.919	Gain
Other_PLK_PLK1_PLK1_ST	O75170	PPP6R2	P53350	PLK1	S830	S825F	825	Missense	distal	-5	no	13.332	13.071	EPSD	COSMIC;CCLE	10.919	Down-regulation
Other_PLK_PLK1_PLK1_ST	O75170	PPP6R2	P53350	PLK1	S830	G827D	827	Missense	distal	-3	no	13.332	12.850	EPSD	COSMIC	10.919	Down-regulation
Other_PLK_PLK1_PLK1_ST	O75170	PPP6R2	P53350	PLK1	S830	D832N	832	Missense	proximal	2	no	13.332	13.547	EPSD	COSMIC	10.919	Up-regulation
Other_PLK_PLK1_PLK1_ST	O75170	PPP6R2	P53350	PLK1	S830	D834E	834	Missense	distal	4	no	13.332	13.318	EPSD	COSMIC	10.919	Down-regulation
Other_PLK_PLK1_PLK1_ST	O75170	PPP6R2	P53350	PLK1	S830	H829Y	829	Missense	proximal	-1	no	13.332	13.607	EPSD	COSMIC	10.919	Up-regulation
Other_PLK_PLK1_PLK1_ST	O75170	PPP6R2	P53350	PLK1	S830	S825C	825	Missense	distal	-5	no	13.332	13.350	EPSD	COSMIC	10.919	Up-regulation
Other_PLK_PLK1_PLK1_ST	O75170	PPP6R2	P53350	PLK1	S920	P916Q	916	Missense	distal	-4	no	11.737	11.581	EPSD	COSMIC	10.919	Down-regulation
Other_PLK_PLK1_PLK1_ST	O75170	PPP6R2	P53350	PLK1	S920	A921S	921	Missense	proximal	1	no	11.737	11.607	EPSD	COSMIC	10.919	Down-regulation
Other_PLK_PLK1_PLK1_ST	O75170	PPP6R2	P53350	PLK1	S920	P916T	916	Missense	distal	-4	no	11.737	11.497	EPSD	COSMIC	10.919	Down-regulation
Other_PLK_PLK1_PLK1_ST	O75170	PPP6R2	P53350	PLK1	S920	A925V	925	Missense	distal	5	no	11.737	10.999	EPSD	COSMIC	10.919	Down-regulation
Other_PLK_PLK1_PLK1_ST	O75170	PPP6R2	P53350	PLK1	S920	P914H	914	Missense	distal	-6	no	11.737	12.372	EPSD	COSMIC	10.919	Up-regulation
Other_PLK_PLK1_PLK1_ST	Q8TCG1	CIP2A	P53350	PLK1	T234	R229Q	229	Missense	distal	-5	no	11.482	10.743	EPSD	COSMIC	10.919	Loss
Other_PLK_PLK1_PLK1_ST	Q8TCG1	CIP2A	P53350	PLK1	T441	T446A	446	Missense	distal	5	no	10.297	11.469	EPSD	COSMIC	10.919	Gain
Other_PLK_PLK1_PLK1_ST	Q8TCG1	CIP2A	P53350	PLK1	S576	W570C	570	Missense	distal	-6	no	13.180	12.881	EPSD	COSMIC	10.919	Down-regulation
Other_PLK_PLK1_PLK1_ST	Q8TCG1	CIP2A	P53350	PLK1	T741	N745K	745	Missense	distal	4	no	11.638	11.488	EPSD	COSMIC	10.919	Down-regulation
Other_PLK_PLK1_PLK1_ST	Q8TCG1	CIP2A	P53350	PLK1	T741	L735F	735	Missense	distal	-6	no	11.638	11.454	EPSD	COSMIC	10.919	Down-regulation
Other_PLK_PLK1_PLK1_ST	Q8TCG1	CIP2A	P53350	PLK1	T741	E742Q	742	Missense	proximal	1	no	11.638	11.761	EPSD	COSMIC	10.919	Up-regulation
Other_PLK_PLK1_PLK1_ST	Q8TCG1	CIP2A	P53350	PLK1	T828	E823G	823	Missense	distal	-5	no	12.546	13.043	EPSD	COSMIC	10.919	Up-regulation
Other_PLK_PLK1_PLK1_ST	Q8TCG1	CIP2A	P53350	PLK1	T828	D824N	824	Missense	distal	-4	no	12.546	12.606	EPSD	COSMIC;GDSC	10.919	Up-regulation
Other_PLK_PLK1_PLK1_ST	Q8TCG1	CIP2A	P53350	PLK1	T828	R822M	822	Missense	distal	-6	no	12.546	12.876	EPSD	COSMIC	10.919	Up-regulation
Other_PLK_PLK1_PLK1_ST	Q8TCG1	CIP2A	P53350	PLK1	T828	T828N	828	Missense	central	0	yes	12.546	0.000	EPSD	COSMIC	10.919	Loss
Other_PLK_PLK1_PLK1_ST	Q8TCG1	CIP2A	P53350	PLK1	T828	E826K	826	Missense	proximal	-2	no	12.546	9.669	EPSD	COSMIC	10.919	Loss
Other_PLK_PLK1_PLK1_ST	Q8TCG1	CIP2A	P53350	PLK1	T828	E827K	827	Missense	proximal	-1	no	12.546	11.975	EPSD	COSMIC	10.919	Down-regulation
Other_PLK_PLK1_PLK1_ST	Q8TCG1	CIP2A	P53350	PLK1	S847	S852F	852	Missense	distal	5	no	12.770	12.864	EPSD	COSMIC	10.919	Up-regulation
Other_PLK_PLK1_PLK1_ST	Q8TCG1	CIP2A	P53350	PLK1	S847	E840K	840	Missense	distal	-7	no	12.770	12.466	EPSD	COSMIC	10.919	Down-regulation
Other_PLK_PLK1_PLK1_ST	Q8TCG1	CIP2A	P53350	PLK1	S847	A850D	850	Missense	distal	3	no	12.770	13.191	EPSD	COSMIC	10.919	Up-regulation
Other_PLK_PLK1_PLK1_ST	Q8TCG1	CIP2A	P53350	PLK1	S847	L846F	846	Missense	proximal	-1	no	12.770	12.691	EPSD	COSMIC	10.919	Down-regulation
Other_PLK_PLK1_PLK1_ST	Q8TCG1	CIP2A	P53350	PLK1	S890	M884V	884	Missense	distal	-6	no	11.574	11.418	EPSD	COSMIC	10.919	Down-regulation
Other_PLK_PLK1_PLK1_ST	Q8TCG1	CIP2A	P53350	PLK1	S890	M884L	884	Missense	distal	-6	no	11.574	11.358	EPSD	COSMIC	10.919	Down-regulation
Other_PLK_PLK1_PLK1_ST	Q8TCG1	CIP2A	P53350	PLK1	S890	G893S	893	Missense	distal	3	no	11.574	11.571	EPSD	COSMIC	10.919	Down-regulation
Other_PLK_PLK1_PLK1_ST	Q8TCG1	CIP2A	P53350	PLK1	S890	G894S	894	Missense	distal	4	no	11.574	11.659	EPSD	COSMIC	10.919	Up-regulation
Other_PLK_PLK1_PLK1_ST	Q8TCG1	CIP2A	P53350	PLK1	S904	N902D	902	Missense	proximal	-2	no	10.022	11.265	PhosphoSitePlus	COSMIC	10.919	Gain
Other_PLK_PLK1_PLK1_ST	O14920	IKBKB	P53350	PLK1	T399	R404Q	404	Missense	distal	5	no	11.782	10.986	EPSD	COSMIC;CCLE	10.919	Down-regulation
Other_PLK_PLK1_PLK1_ST	O14920	IKBKB	P53350	PLK1	T399	S402F	402	Missense	distal	3	no	11.782	11.842	EPSD	COSMIC	10.919	Up-regulation
Other_PLK_PLK1_PLK1_ST	O14920	IKBKB	P53350	PLK1	T399	R404L	404	Missense	distal	5	no	11.782	11.091	EPSD	COSMIC	10.919	Down-regulation
Other_PLK_PLK1_PLK1_ST	O14920	IKBKB	P53350	PLK1	S402	R404Q	404	Missense	proximal	2	no	11.315	11.640	EPSD	COSMIC;CCLE	10.919	Up-regulation
Other_PLK_PLK1_PLK1_ST	O14920	IKBKB	P53350	PLK1	S402	S402F	402	Missense	central	0	yes	11.315	0.000	EPSD	COSMIC	10.919	Loss
Other_PLK_PLK1_PLK1_ST	O14920	IKBKB	P53350	PLK1	S402	R404L	404	Missense	proximal	2	no	11.315	12.114	EPSD	COSMIC	10.919	Up-regulation
Other_PLK_PLK1_PLK1_ST	O14920	IKBKB	P53350	PLK1	S550	D543N	543	Missense	distal	-7	no	11.849	11.989	EPSD	COSMIC	10.919	Up-regulation
Other_PLK_PLK1_PLK1_ST	O14920	IKBKB	P53350	PLK1	S692	T693M	693	Missense	proximal	1	no	9.997	12.129	EPSD	COSMIC;CCLE	10.919	Gain
Other_PLK_PLK1_PLK1_ST	O14920	IKBKB	P53350	PLK1	S733	D738Y	738	Missense	distal	5	no	16.117	15.811	EPSD;PhosphoSitePlus	COSMIC	10.919	Down-regulation
Other_PLK_PLK1_PLK1_ST	O14920	IKBKB	P53350	PLK1	S740	E745A	745	Missense	distal	5	no	12.084	12.943	PhosphoSitePlus;EPSD	COSMIC	10.919	Up-regulation
Other_PLK_PLK1_PLK1_ST	O14920	IKBKB	P53350	PLK1	S740	E746Q	746	Missense	distal	6	no	12.084	11.944	PhosphoSitePlus;EPSD	COSMIC	10.919	Down-regulation
Other_PLK_PLK1_PLK1_ST	O14920	IKBKB	P53350	PLK1	S740	D738Y	738	Missense	proximal	-2	no	12.084	10.543	PhosphoSitePlus;EPSD	COSMIC	10.919	Loss
Other_PLK_PLK1_PLK1_ST	O14920	IKBKB	P53350	PLK1	S750	E745A	745	Missense	distal	-5	no	13.980	14.361	EPSD;PhosphoSitePlus	COSMIC	10.919	Up-regulation
Other_PLK_PLK1_PLK1_ST	O14920	IKBKB	P53350	PLK1	S750	E746Q	746	Missense	distal	-4	no	13.980	13.711	EPSD;PhosphoSitePlus	COSMIC	10.919	Down-regulation
Other_PLK_PLK1_PLK1_ST	O14920	IKBKB	P53350	PLK1	S750	H749N	749	Missense	proximal	-1	no	13.980	13.779	EPSD;PhosphoSitePlus	COSMIC	10.919	Down-regulation
Other_PLK_PLK1_PLK1_ST	Q9NYZ3	GTSE1	P53350	PLK1	S168	G175W	175	Missense	distal	7	no	10.915	10.951	EPSD	COSMIC	10.919	Gain
Other_PLK_PLK1_PLK1_ST	Q9NYZ3	GTSE1	P53350	PLK1	S174	G175E	175	Missense	proximal	1	no	10.932	10.686	EPSD	COSMIC	10.919	Loss
Other_PLK_PLK1_PLK1_ST	Q9NYZ3	GTSE1	P53350	PLK1	S174	G175W	175	Missense	proximal	1	no	10.932	11.534	EPSD	COSMIC	10.919	Up-regulation
Other_PLK_PLK1_PLK1_ST	P11388	TOP2A	P53350	PLK1	S714	P716S	716	Missense	proximal	2	no	10.253	11.729	EPSD	COSMIC	10.919	Gain
Other_PLK_PLK1_PLK1_ST	P11388	TOP2A	P53350	PLK1	T808	M809V	809	Missense	proximal	1	no	11.534	10.378	EPSD	COSMIC	10.919	Loss
Other_PLK_PLK1_PLK1_ST	P11388	TOP2A	P53350	PLK1	T825	H824Q	824	Missense	proximal	-1	no	11.513	11.119	EPSD	COSMIC	10.919	Down-regulation
Other_PLK_PLK1_PLK1_ST	P11388	TOP2A	P53350	PLK1	S1106	K1110E	1110	Missense	distal	4	no	14.821	15.195	EPSD	COSMIC;GDSC	10.919	Up-regulation
Other_PLK_PLK1_PLK1_ST	P11388	TOP2A	P53350	PLK1	S1115	K1110E	1110	Missense	distal	-5	no	13.258	13.015	EPSD	COSMIC;GDSC	10.919	Down-regulation
Other_PLK_PLK1_PLK1_ST	P11388	TOP2A	P53350	PLK1	S1117	K1110E	1110	Missense	distal	-7	no	12.973	13.277	EPSD	COSMIC;GDSC	10.919	Up-regulation
Other_PLK_PLK1_PLK1_ST	P11388	TOP2A	P53350	PLK1	S1303	D1304G	1304	Missense	proximal	1	no	11.790	11.793	EPSD	COSMIC	10.919	Up-regulation
Other_PLK_PLK1_PLK1_ST	P11388	TOP2A	P53350	PLK1	S1306	P1312S	1312	Missense	distal	6	no	11.267	11.123	EPSD	COSMIC	10.919	Down-regulation
Other_PLK_PLK1_PLK1_ST	P11388	TOP2A	P53350	PLK1	S1306	D1304G	1304	Missense	proximal	-2	no	11.267	7.945	EPSD	COSMIC	10.919	Loss
Other_PLK_PLK1_PLK1_ST	P11388	TOP2A	P53350	PLK1	S1423	S1425F	1425	Missense	proximal	2	no	11.535	10.983	EPSD	COSMIC;GDSC;CCLE	10.919	Down-regulation
Other_PLK_PLK1_PLK1_ST	P11388	TOP2A	P53350	PLK1	S1423	S1423I	1423	Missense	central	0	yes	11.535	0.000	EPSD	COSMIC	10.919	Loss
Other_PLK_PLK1_PLK1_ST	P11388	TOP2A	P53350	PLK1	T1430	K1434I	1434	Missense	distal	4	no	11.178	10.372	EPSD	COSMIC	10.919	Loss
Other_PLK_PLK1_PLK1_ST	P11388	TOP2A	P53350	PLK1	T1430	S1425F	1425	Missense	distal	-5	no	11.178	10.917	EPSD	COSMIC;GDSC;CCLE	10.919	Loss
Other_PLK_PLK1_PLK1_ST	P11388	TOP2A	P53350	PLK1	T1430	S1423I	1423	Missense	distal	-7	no	11.178	10.716	EPSD	COSMIC	10.919	Loss
Other_PLK_PLK1_PLK1_ST	P11388	TOP2A	P53350	PLK1	S1469	R1463C	1463	Missense	distal	-6	no	10.934	10.178	EPSD	COSMIC;GDSC;CCLE	10.919	Loss
Other_PLK_PLK1_PLK1_ST	P11388	TOP2A	P53350	PLK1	S1469	R1464H	1464	Missense	distal	-5	no	10.934	10.131	EPSD	COSMIC	10.919	Loss
Other_PLK_PLK1_PLK1_ST	P11388	TOP2A	P53350	PLK1	S1476	F1478I	1478	Missense	proximal	2	no	11.082	12.055	EPSD	COSMIC	10.919	Up-regulation
Other_PLK_PLK1_PLK1_ST	P11388	TOP2A	P53350	PLK1	S1512	R1514L	1514	Missense	proximal	2	no	11.979	12.778	EPSD	COSMIC	10.919	Up-regulation
Other_PLK_PLK1_PLK1_ST	Q9UBW7	ZMYM2	P53350	PLK1	S53	D59H	59	Missense	distal	6	no	12.847	12.053	EPSD	COSMIC	10.919	Down-regulation
Other_PLK_PLK1_PLK1_ST	Q9UBW7	ZMYM2	P53350	PLK1	S53	K48Q	48	Missense	distal	-5	no	12.847	12.646	EPSD	COSMIC	10.919	Down-regulation
Other_PLK_PLK1_PLK1_ST	Q9UBW7	ZMYM2	P53350	PLK1	S53	S52L	52	Missense	proximal	-1	no	12.847	12.387	EPSD	COSMIC	10.919	Down-regulation
Other_PLK_PLK1_PLK1_ST	Q9UBW7	ZMYM2	P53350	PLK1	S136	G130R	130	Missense	distal	-6	no	11.403	11.502	EPSD	COSMIC	10.919	Up-regulation
Other_PLK_PLK1_PLK1_ST	Q9UBW7	ZMYM2	P53350	PLK1	S136	I139V	139	Missense	distal	3	no	11.403	11.526	EPSD	COSMIC	10.919	Up-regulation
Other_PLK_PLK1_PLK1_ST	Q9UBW7	ZMYM2	P53350	PLK1	S136	R141Q	141	Missense	distal	5	no	11.403	10.608	EPSD	COSMIC	10.919	Loss
Other_PLK_PLK1_PLK1_ST	Q9UBW7	ZMYM2	P53350	PLK1	S156	R162K	162	Missense	distal	6	no	10.884	11.244	EPSD	COSMIC	10.919	Gain
Other_PLK_PLK1_PLK1_ST	Q9UBW7	ZMYM2	P53350	PLK1	S159	R162K	162	Missense	distal	3	no	13.793	13.891	EPSD	COSMIC	10.919	Up-regulation
Other_PLK_PLK1_PLK1_ST	Q9UBW7	ZMYM2	P53350	PLK1	S309	P311L	311	Missense	proximal	2	no	10.770	12.318	EPSD;PhosphoSitePlus	COSMIC	10.919	Gain
Other_PLK_PLK1_PLK1_ST	Q9UBW7	ZMYM2	P53350	PLK1	S439	M443T	443	Missense	distal	4	no	11.028	11.785	EPSD	COSMIC;GDSC;CCLE	10.919	Up-regulation
Other_PLK_PLK1_PLK1_ST	Q9UBW7	ZMYM2	P53350	PLK1	S522	F523V	523	Missense	proximal	1	no	12.281	10.801	EPSD	COSMIC	10.919	Loss
Other_PLK_PLK1_PLK1_ST	Q9UBW7	ZMYM2	P53350	PLK1	S522	R516Q	516	Missense	distal	-6	no	12.281	12.729	EPSD	COSMIC	10.919	Up-regulation
Other_PLK_PLK1_PLK1_ST	Q9UBW7	ZMYM2	P53350	PLK1	S1056	D1062Y	1062	Missense	distal	6	no	12.321	11.522	EPSD	COSMIC	10.919	Down-regulation
Other_PLK_PLK1_PLK1_ST	Q9UBW7	ZMYM2	P53350	PLK1	S1056	K1049M	1049	Missense	distal	-7	no	12.321	12.256	EPSD	COSMIC	10.919	Down-regulation
Other_PLK_PLK1_PLK1_ST	Q9UBW7	ZMYM2	P53350	PLK1	S1061	D1062Y	1062	Missense	proximal	1	no	13.211	13.014	EPSD	COSMIC	10.919	Down-regulation
Other_PLK_PLK1_PLK1_ST	Q9UBW7	ZMYM2	P53350	PLK1	S1061	C1066Y	1066	Missense	distal	5	no	13.211	12.925	EPSD	COSMIC;GDSC;CCLE	10.919	Down-regulation
Other_PLK_PLK1_PLK1_ST	Q9UBW7	ZMYM2	P53350	PLK1	S1064	C1066Y	1066	Missense	proximal	2	no	10.884	11.489	EPSD	COSMIC;GDSC;CCLE	10.919	Gain
Other_PLK_PLK1_PLK1_ST	Q9UBW7	ZMYM2	P53350	PLK1	S1067	D1062Y	1062	Missense	distal	-5	no	12.667	12.522	EPSD	COSMIC	10.919	Down-regulation
Other_PLK_PLK1_PLK1_ST	Q9UBW7	ZMYM2	P53350	PLK1	S1067	C1066Y	1066	Missense	proximal	-1	no	12.667	14.863	EPSD	COSMIC;GDSC;CCLE	10.919	Up-regulation
Other_PLK_PLK1_PLK1_ST	Q8NHV4	NEDD1	P53350	PLK1	S89	V83A	83	Missense	distal	-6	no	10.696	10.935	EPSD	COSMIC	10.919	Gain
Other_PLK_PLK1_PLK1_ST	Q8NHV4	NEDD1	P53350	PLK1	T100	G95R	95	Missense	distal	-5	no	12.667	12.952	EPSD	COSMIC	10.919	Up-regulation
Other_PLK_PLK1_PLK1_ST	Q8NHV4	NEDD1	P53350	PLK1	T100	N102H	102	Missense	proximal	2	no	12.667	12.428	EPSD	COSMIC	10.919	Down-regulation
Other_PLK_PLK1_PLK1_ST	Q8NHV4	NEDD1	P53350	PLK1	S171	R166W	166	Missense	distal	-5	no	11.265	11.032	EPSD	COSMIC	10.919	Down-regulation
Other_PLK_PLK1_PLK1_ST	Q8NHV4	NEDD1	P53350	PLK1	S171	H167Y	167	Missense	distal	-4	no	11.265	10.843	EPSD	COSMIC	10.919	Loss
Other_PLK_PLK1_PLK1_ST	Q8NHV4	NEDD1	P53350	PLK1	S171	V165F	165	Missense	distal	-6	no	11.265	11.022	EPSD	COSMIC	10.919	Down-regulation
Other_PLK_PLK1_PLK1_ST	Q8NHV4	NEDD1	P53350	PLK1	T286	L280F	280	Missense	distal	-6	no	12.204	12.021	EPSD	COSMIC	10.919	Down-regulation
Other_PLK_PLK1_PLK1_ST	Q8NHV4	NEDD1	P53350	PLK1	T303	C296S	296	Missense	distal	-7	no	10.347	10.965	EPSD	COSMIC	10.919	Gain
Other_PLK_PLK1_PLK1_ST	Q8NHV4	NEDD1	P53350	PLK1	S325	V328E	328	Missense	distal	3	no	12.356	12.384	EPSD	COSMIC;CCLE	10.919	Up-regulation
Other_PLK_PLK1_PLK1_ST	Q8NHV4	NEDD1	P53350	PLK1	S325	N329I	329	Missense	distal	4	no	12.356	11.400	EPSD	COSMIC;CCLE	10.919	Down-regulation
Other_PLK_PLK1_PLK1_ST	Q8NHV4	NEDD1	P53350	PLK1	S325	V321A	321	Missense	distal	-4	no	12.356	12.496	EPSD	COSMIC	10.919	Up-regulation
Other_PLK_PLK1_PLK1_ST	Q8NHV4	NEDD1	P53350	PLK1	S325	V328A	328	Missense	distal	3	no	12.356	12.028	EPSD	COSMIC	10.919	Down-regulation
Other_PLK_PLK1_PLK1_ST	Q8NHV4	NEDD1	P53350	PLK1	S460	S455L	455	Missense	distal	-5	no	10.676	11.340	EPSD	COSMIC;CCLE	10.919	Gain
Other_PLK_PLK1_PLK1_ST	Q8NHV4	NEDD1	P53350	PLK1	S525	N524I	524	Missense	proximal	-1	no	10.929	11.086	EPSD	COSMIC	10.919	Up-regulation
Other_PLK_PLK1_PLK1_ST	Q8NHV4	NEDD1	P53350	PLK1	S525	T522A	522	Missense	distal	-3	no	10.929	11.075	EPSD	COSMIC	10.919	Up-regulation
Other_PLK_PLK1_PLK1_ST	Q8NHV4	NEDD1	P53350	PLK1	S525	N520K	520	Missense	distal	-5	no	10.929	11.127	EPSD	COSMIC	10.919	Up-regulation
Other_PLK_PLK1_PLK1_ST	Q8NHV4	NEDD1	P53350	PLK1	S525	S518L	518	Missense	distal	-7	no	10.929	10.624	EPSD	COSMIC	10.919	Loss
Other_PLK_PLK1_PLK1_ST	Q8NHV4	NEDD1	P53350	PLK1	S525	S525L	525	Missense	central	0	yes	10.929	0.000	EPSD	COSMIC	10.919	Loss
Other_PLK_PLK1_PLK1_ST	Q8NHV4	NEDD1	P53350	PLK1	S558	P551A	551	Missense	distal	-7	no	11.286	11.143	EPSD	COSMIC	10.919	Down-regulation
Other_PLK_PLK1_PLK1_ST	Q8NHV4	NEDD1	P53350	PLK1	S558	G562E	562	Missense	distal	4	no	11.286	11.360	EPSD	COSMIC	10.919	Up-regulation
Other_PLK_PLK1_PLK1_ST	Q8NHV4	NEDD1	P53350	PLK1	S566	G562E	562	Missense	distal	-4	no	10.563	11.207	EPSD	COSMIC	10.919	Gain
Other_PLK_PLK1_PLK1_ST	Q8NHV4	NEDD1	P53350	PLK1	S574	R579Q	579	Missense	distal	5	no	11.859	11.063	EPSD	COSMIC	10.919	Down-regulation
Other_PLK_PLK1_PLK1_ST	Q8NHV4	NEDD1	P53350	PLK1	S574	A572V	572	Missense	proximal	-2	no	11.859	11.819	EPSD	COSMIC;CCLE	10.919	Down-regulation
Other_PLK_PLK1_PLK1_ST	Q8NHV4	NEDD1	P53350	PLK1	S637	Y636H	636	Missense	proximal	-1	no	12.013	11.738	PhosphoSitePlus;EPSD	COSMIC;CCLE	10.919	Down-regulation
Other_PLK_PLK1_PLK1_ST	Q8NHV4	NEDD1	P53350	PLK1	S637	S631F	631	Missense	distal	-6	no	12.013	11.495	PhosphoSitePlus;EPSD	COSMIC	10.919	Down-regulation
Other_PLK_PLK1_PLK1_ST	Q13042	CDC16	P53350	PLK1	S118	D120V	120	Missense	proximal	2	no	11.095	11.300	EPSD	COSMIC;GDSC;CCLE	10.919	Up-regulation
Other_PLK_PLK1_PLK1_ST	Q13042	CDC16	P53350	PLK1	S124	D120V	120	Missense	distal	-4	no	11.071	11.164	EPSD	COSMIC;GDSC;CCLE	10.919	Up-regulation
Other_PLK_PLK1_PLK1_ST	Q13042	CDC16	P53350	PLK1	S324	Y322H	322	Missense	proximal	-2	no	11.458	9.812	EPSD	COSMIC	10.919	Loss
Other_PLK_PLK1_PLK1_ST	Q13042	CDC16	P53350	PLK1	S324	A326V	326	Missense	proximal	2	no	11.458	11.901	EPSD	COSMIC	10.919	Up-regulation
Other_PLK_PLK1_PLK1_ST	Q13042	CDC16	P53350	PLK1	S607	D608Y	608	Missense	proximal	1	no	14.099	13.902	EPSD	COSMIC	10.919	Down-regulation
Other_PLK_PLK1_PLK1_ST	Q13042	CDC16	P53350	PLK1	S607	M609L	609	Missense	proximal	2	no	14.099	14.173	EPSD	COSMIC	10.919	Up-regulation
Other_PLK_PLK1_PLK1_ST	Q13042	CDC16	P53350	PLK1	S614	M615I	615	Missense	proximal	1	no	14.760	13.795	EPSD	COSMIC	10.919	Down-regulation
Other_PLK_PLK1_PLK1_ST	Q13042	CDC16	P53350	PLK1	S614	D608Y	608	Missense	distal	-6	no	14.760	13.991	EPSD	COSMIC	10.919	Down-regulation
Other_PLK_PLK1_PLK1_ST	Q13042	CDC16	P53350	PLK1	S614	M609L	609	Missense	distal	-5	no	14.760	15.360	EPSD	COSMIC	10.919	Up-regulation
Other_PLK_PLK1_PLK1_ST	Q13042	CDC16	P53350	PLK1	S616	M615I	615	Missense	proximal	-1	no	11.096	11.041	EPSD	COSMIC	10.919	Down-regulation
Other_PLK_PLK1_PLK1_ST	Q13042	CDC16	P53350	PLK1	S616	M609L	609	Missense	distal	-7	no	11.096	11.221	EPSD	COSMIC	10.919	Up-regulation
Other_PLK_PLK1_PLK1_ST	Q13042	CDC16	P53350	PLK1	S619	M615I	615	Missense	distal	-4	no	11.703	12.012	EPSD	COSMIC	10.919	Up-regulation
Other_PLK_PLK1_PLK1_ST	P18031	PTPN1	P53350	PLK1	S13	A17T	17	Missense	distal	4	no	11.426	11.432	EPSD	COSMIC	10.919	Up-regulation
Other_PLK_PLK1_PLK1_ST	P18031	PTPN1	P53350	PLK1	S50	I57V	57	Missense	distal	7	no	15.413	15.429	EPSD	COSMIC;GDSC;CCLE	10.919	Up-regulation
Other_PLK_PLK1_PLK1_ST	P18031	PTPN1	P53350	PLK1	S50	F52L	52	Missense	proximal	2	no	15.413	16.036	EPSD	COSMIC	10.919	Up-regulation
Other_PLK_PLK1_PLK1_ST	P18031	PTPN1	P53350	PLK1	S55	F52L	52	Missense	distal	-3	no	10.600	12.004	EPSD	COSMIC	10.919	Gain
Other_PLK_PLK1_PLK1_ST	P18031	PTPN1	P53350	PLK1	S203	G202E	202	Missense	proximal	-1	no	9.771	11.564	EPSD	COSMIC	10.919	Gain
Other_PLK_PLK1_PLK1_ST	P18031	PTPN1	P53350	PLK1	S363	E369A	369	Missense	distal	6	no	10.884	11.045	EPSD	COSMIC	10.919	Gain
Other_PLK_PLK1_PLK1_ST	P18031	PTPN1	P53350	PLK1	S378	G377R	377	Missense	proximal	-1	no	10.600	11.461	EPSD	COSMIC	10.919	Gain
Other_PLK_PLK1_PLK1_ST	P18031	PTPN1	P53350	PLK1	S386	A385S	385	Missense	proximal	-1	no	10.468	10.936	EPSD	COSMIC	10.919	Gain
Other_PLK_PLK1_PLK1_ST	P18031	PTPN1	P53350	PLK1	S386	P387L	387	Missense	proximal	1	no	10.468	11.314	EPSD	COSMIC	10.919	Gain
Other_PLK_PLK1_PLK1_ST	P18031	PTPN1	P53350	PLK1	S393	P395L	395	Missense	proximal	2	no	11.750	13.298	EPSD;PhosphoSitePlus	COSMIC	10.919	Up-regulation
Other_PLK_PLK1_PLK1_ST	P18031	PTPN1	P53350	PLK1	S393	P392L	392	Missense	proximal	-1	no	11.750	12.465	EPSD;PhosphoSitePlus	COSMIC	10.919	Up-regulation
Other_PLK_PLK1_PLK1_ST	P18031	PTPN1	P53350	PLK1	S393	P387T	387	Missense	distal	-6	no	11.750	12.271	EPSD;PhosphoSitePlus	COSMIC	10.919	Up-regulation
Other_PLK_PLK1_PLK1_ST	P18031	PTPN1	P53350	PLK1	S393	K397R	397	Missense	distal	4	no	11.750	11.191	EPSD;PhosphoSitePlus	COSMIC	10.919	Down-regulation
Other_PLK_PLK1_PLK1_ST	P18031	PTPN1	P53350	PLK1	S393	K389N	389	Missense	distal	-4	no	11.750	12.008	EPSD;PhosphoSitePlus	COSMIC	10.919	Up-regulation
Other_PLK_PLK1_PLK1_ST	P18031	PTPN1	P53350	PLK1	S393	P387L	387	Missense	distal	-6	no	11.750	12.039	EPSD;PhosphoSitePlus	COSMIC	10.919	Up-regulation
Other_PLK_PLK1_PLK1_ST	Q8N4N8	KIF2B	P53350	PLK1	T125	S127L	127	Missense	proximal	2	no	11.675	11.746	PhosphoSitePlus;EPSD	COSMIC	10.919	Up-regulation
Other_PLK_PLK1_PLK1_ST	Q8N4N8	KIF2B	P53350	PLK1	T125	D129G	129	Missense	distal	4	no	11.675	11.587	PhosphoSitePlus;EPSD	COSMIC	10.919	Down-regulation
Other_PLK_PLK1_PLK1_ST	Q8N4N8	KIF2B	P53350	PLK1	T125	D132N	132	Missense	distal	7	no	11.675	11.757	PhosphoSitePlus;EPSD	COSMIC;GDSC;CCLE	10.919	Up-regulation
Other_PLK_PLK1_PLK1_ST	Q8N4N8	KIF2B	P53350	PLK1	T125	Q124K	124	Missense	proximal	-1	no	11.675	11.432	PhosphoSitePlus;EPSD	COSMIC	10.919	Down-regulation
Other_PLK_PLK1_PLK1_ST	Q8N4N8	KIF2B	P53350	PLK1	T125	K122N	122	Missense	distal	-3	no	11.675	11.493	PhosphoSitePlus;EPSD	COSMIC	10.919	Down-regulation
Other_PLK_PLK1_PLK1_ST	Q8N4N8	KIF2B	P53350	PLK1	T125	D129Y	129	Missense	distal	4	no	11.675	11.429	PhosphoSitePlus;EPSD	COSMIC;CCLE	10.919	Down-regulation
Other_PLK_PLK1_PLK1_ST	Q8N4N8	KIF2B	P53350	PLK1	S204	K202N	202	Missense	proximal	-2	no	10.454	12.482	EPSD;PhosphoSitePlus	COSMIC	10.919	Gain
Other_PLK_PLK1_PLK1_ST	Q8N4N8	KIF2B	P53350	PLK1	S204	S201R	201	Missense	distal	-3	no	10.454	11.286	EPSD;PhosphoSitePlus	COSMIC	10.919	Gain
Other_PLK_PLK1_PLK1_ST	Q8N4N8	KIF2B	P53350	PLK1	S444	L445F	445	Missense	proximal	1	no	10.813	11.894	EPSD	COSMIC	10.919	Gain
Other_PLK_PLK1_PLK1_ST	Q8N4N8	KIF2B	P53350	PLK1	S444	R437L	437	Missense	distal	-7	no	10.813	11.006	EPSD	COSMIC;GDSC;CCLE	10.919	Gain
Other_PLK_PLK1_PLK1_ST	Q8N4N8	KIF2B	P53350	PLK1	S444	G450V	450	Missense	distal	6	no	10.813	11.125	EPSD	COSMIC	10.919	Gain
Other_PLK_PLK1_PLK1_ST	Q8N4N8	KIF2B	P53350	PLK1	S474	G468E	468	Missense	distal	-6	no	12.257	12.922	EPSD	COSMIC;GDSC	10.919	Up-regulation
Other_PLK_PLK1_PLK1_ST	Q8N4N8	KIF2B	P53350	PLK1	S474	S474C	474	Missense	central	0	yes	12.257	0.000	EPSD	COSMIC	10.919	Loss
Other_PLK_PLK1_PLK1_ST	Q8N4N8	KIF2B	P53350	PLK1	S474	L476I	476	Missense	proximal	2	no	12.257	12.606	EPSD	COSMIC	10.919	Up-regulation
Other_PLK_PLK1_PLK1_ST	Q8N4N8	KIF2B	P53350	PLK1	S474	K479N	479	Missense	distal	5	no	12.257	11.934	EPSD	COSMIC	10.919	Down-regulation
Other_PLK_PLK1_PLK1_ST	Q8N4N8	KIF2B	P53350	PLK1	S575	M574I	574	Missense	proximal	-1	no	11.721	11.666	EPSD	COSMIC	10.919	Down-regulation
Other_PLK_PLK1_PLK1_ST	Q8N4N8	KIF2B	P53350	PLK1	S575	M574T	574	Missense	proximal	-1	no	11.721	10.902	EPSD	COSMIC	10.919	Loss
Other_PLK_PLK1_PLK1_ST	Q8N4N8	KIF2B	P53350	PLK1	S575	I582L	582	Missense	distal	7	no	11.721	11.687	EPSD	COSMIC	10.919	Down-regulation
Other_PLK_PLK1_PLK1_ST	Q8N4N8	KIF2B	P53350	PLK1	S575	E573K	573	Missense	proximal	-2	no	11.721	8.843	EPSD	COSMIC	10.919	Loss
Other_PLK_PLK1_PLK1_ST	Q8N4N8	KIF2B	P53350	PLK1	S575	S572A	572	Missense	distal	-3	no	11.721	12.243	EPSD	COSMIC	10.919	Up-regulation
Other_PLK_PLK1_PLK1_ST	Q8N4N8	KIF2B	P53350	PLK1	S575	H568Q	568	Missense	distal	-7	no	11.721	11.741	EPSD	COSMIC	10.919	Up-regulation
Other_PLK_PLK1_PLK1_ST	Q8N4N8	KIF2B	P53350	PLK1	S575	D579E	579	Missense	distal	4	no	11.721	11.706	EPSD	COSMIC	10.919	Down-regulation
Other_PLK_PLK1_PLK1_ST	Q8N4N8	KIF2B	P53350	PLK1	T610	S616C	616	Missense	distal	6	no	11.387	10.454	EPSD	COSMIC	10.919	Loss
Other_PLK_PLK1_PLK1_ST	Q8N4N8	KIF2B	P53350	PLK1	T610	G606A	606	Missense	distal	-4	no	11.387	12.080	EPSD	COSMIC	10.919	Up-regulation
Other_PLK_PLK1_PLK1_ST	Q8N4N8	KIF2B	P53350	PLK1	T610	G615R	615	Missense	distal	5	no	11.387	11.549	EPSD	COSMIC	10.919	Up-regulation
Other_PLK_PLK1_PLK1_ST	Q8N4N8	KIF2B	P53350	PLK1	T610	L604Q	604	Missense	distal	-6	no	11.387	11.721	EPSD	COSMIC	10.919	Up-regulation
Other_PLK_PLK1_PLK1_ST	Q8N4N8	KIF2B	P53350	PLK1	T653	A651D	651	Missense	proximal	-2	no	9.257	11.828	EPSD	COSMIC	10.919	Gain
Other_PLK_PLK1_PLK1_ST	P0DMV8	HSPA1A	P53350	PLK1	T419	I414M	414	Missense	distal	-5	no	11.320	11.016	EPSD	COSMIC	10.919	Down-regulation
Other_PLK_PLK1_PLK1_ST	P0DMV8	HSPA1A	P53350	PLK1	S544	A546V	546	Missense	proximal	2	no	11.463	11.907	EPSD	COSMIC	10.919	Up-regulation
Other_PLK_PLK1_PLK1_ST	Q9Y5T5	USP16	P53350	PLK1	S16	E21Q	21	Missense	distal	5	no	13.082	12.923	EPSD	COSMIC	10.919	Down-regulation
Other_PLK_PLK1_PLK1_ST	Q9Y5T5	USP16	P53350	PLK1	S16	L20F	20	Missense	distal	4	no	13.082	12.881	EPSD	COSMIC	10.919	Down-regulation
Other_PLK_PLK1_PLK1_ST	Q9Y5T5	USP16	P53350	PLK1	S17	E21Q	21	Missense	distal	4	no	14.836	14.432	EPSD	COSMIC	10.919	Down-regulation
Other_PLK_PLK1_PLK1_ST	Q9Y5T5	USP16	P53350	PLK1	S17	L20F	20	Missense	distal	3	no	14.836	15.042	EPSD	COSMIC	10.919	Up-regulation
Other_PLK_PLK1_PLK1_ST	Q9Y5T5	USP16	P53350	PLK1	T19	E21Q	21	Missense	proximal	2	no	10.916	11.105	EPSD	COSMIC	10.919	Gain
Other_PLK_PLK1_PLK1_ST	Q9Y5T5	USP16	P53350	PLK1	T19	L20F	20	Missense	proximal	1	no	10.916	11.997	EPSD	COSMIC	10.919	Gain
Other_PLK_PLK1_PLK1_ST	Q9Y5T5	USP16	P53350	PLK1	S353	R357S	357	Missense	distal	4	no	10.779	11.724	EPSD	COSMIC	10.919	Gain
Other_PLK_PLK1_PLK1_ST	Q9Y5T5	USP16	P53350	PLK1	S353	R357C	357	Missense	distal	4	no	10.779	11.197	EPSD	COSMIC	10.919	Gain
Other_PLK_PLK1_PLK1_ST	Q9Y5T5	USP16	P53350	PLK1	S386	L387I	387	Missense	proximal	1	no	12.959	12.751	EPSD;PhosphoSitePlus	COSMIC;GDSC;CCLE	10.919	Down-regulation
Other_PLK_PLK1_PLK1_ST	Q9Y5T5	USP16	P53350	PLK1	S386	L383I	383	Missense	distal	-3	no	12.959	12.584	EPSD;PhosphoSitePlus	COSMIC	10.919	Down-regulation
Other_PLK_PLK1_PLK1_ST	Q9Y5T5	USP16	P53350	PLK1	S386	P388T	388	Missense	proximal	2	no	12.959	13.795	EPSD;PhosphoSitePlus	COSMIC	10.919	Up-regulation
Other_PLK_PLK1_PLK1_ST	Q9Y5T5	USP16	P53350	PLK1	S423	D422N	422	Missense	proximal	-1	no	10.964	10.031	EPSD	COSMIC	10.919	Loss
Other_PLK_PLK1_PLK1_ST	Q9Y5T5	USP16	P53350	PLK1	S423	E427K	427	Missense	distal	4	no	10.964	10.591	EPSD	COSMIC	10.919	Loss
Other_PLK_PLK1_PLK1_ST	Q9Y5T5	USP16	P53350	PLK1	S486	G489R	489	Missense	distal	3	no	13.918	13.791	EPSD;PhosphoSitePlus	COSMIC	10.919	Down-regulation
Other_PLK_PLK1_PLK1_ST	Q9Y5T5	USP16	P53350	PLK1	S486	E484V	484	Missense	proximal	-2	no	13.918	11.699	EPSD;PhosphoSitePlus	COSMIC	10.919	Down-regulation
Other_PLK_PLK1_PLK1_ST	Q9Y5T5	USP16	P53350	PLK1	S486	E480V	480	Missense	distal	-6	no	13.918	13.524	EPSD;PhosphoSitePlus	COSMIC	10.919	Down-regulation
Other_PLK_PLK1_PLK1_ST	Q9Y5T5	USP16	P53350	PLK1	S486	E480K	480	Missense	distal	-6	no	13.918	13.344	EPSD;PhosphoSitePlus	COSMIC	10.919	Down-regulation
Other_PLK_PLK1_PLK1_ST	Q9Y5T5	USP16	P53350	PLK1	S598	T603I	603	Missense	distal	5	no	10.878	11.781	EPSD	COSMIC	10.919	Gain
Other_PLK_PLK1_PLK1_ST	Q9Y5T5	USP16	P53350	PLK1	S751	H758L	758	Missense	distal	7	no	11.608	11.620	EPSD	COSMIC;GDSC	10.919	Up-regulation
Other_PLK_PLK1_PLK1_ST	O14641	DVL2	P53350	PLK1	S158	S155L	155	Missense	distal	-3	no	10.342	11.116	EPSD	COSMIC	10.919	Gain
Other_PLK_PLK1_PLK1_ST	O14641	DVL2	P53350	PLK1	S170	G175W	175	Missense	distal	5	no	13.804	13.708	EPSD	COSMIC	10.919	Down-regulation
Other_PLK_PLK1_PLK1_ST	O14641	DVL2	P53350	PLK1	S170	H172D	172	Missense	proximal	2	no	13.804	13.828	EPSD	COSMIC;CCLE	10.919	Up-regulation
Other_PLK_PLK1_PLK1_ST	O14641	DVL2	P53350	PLK1	T216	E214G	214	Missense	proximal	-2	no	13.308	10.380	EPSD	COSMIC	10.919	Loss
Other_PLK_PLK1_PLK1_ST	O14641	DVL2	P53350	PLK1	S223	T224M	224	Missense	proximal	1	no	10.271	12.403	EPSD	COSMIC	10.919	Gain
Other_PLK_PLK1_PLK1_ST	O14641	DVL2	P53350	PLK1	S298	G303R	303	Missense	distal	5	no	11.590	11.752	EPSD	COSMIC	10.919	Up-regulation
Other_PLK_PLK1_PLK1_ST	O14641	DVL2	P53350	PLK1	T364	P359T	359	Missense	distal	-5	no	11.285	11.237	EPSD	COSMIC;GDSC;CCLE	10.919	Down-regulation
Other_PLK_PLK1_PLK1_ST	O14641	DVL2	P53350	PLK1	S618	G617S	617	Missense	proximal	-1	no	10.085	11.883	EPSD	COSMIC;GDSC;CCLE	10.919	Gain
Other_PLK_PLK1_PLK1_ST	O14641	DVL2	P53350	PLK1	S720	R718C	718	Missense	proximal	-2	no	12.586	10.412	EPSD	COSMIC	10.919	Loss
Other_PLK_PLK1_PLK1_ST	O14641	DVL2	P53350	PLK1	S720	T715P	715	Missense	distal	-5	no	12.586	12.633	EPSD	COSMIC	10.919	Up-regulation
Other_PLK_PLK1_PLK1_ST	Q3KR16	PLEKHG6	P53350	PLK1	S550	G549S	549	Missense	proximal	-1	no	10.282	12.079	EPSD	COSMIC	10.919	Gain
Other_PLK_PLK1_PLK1_ST	Q3KR16	PLEKHG6	P53350	PLK1	S697	R691Q	691	Missense	distal	-6	no	11.074	11.522	EPSD	COSMIC	10.919	Up-regulation
Other_PLK_PLK1_PLK1_ST	Q3KR16	PLEKHG6	P53350	PLK1	S712	E706K	706	Missense	distal	-6	no	12.486	11.913	EPSD	COSMIC	10.919	Down-regulation
Other_PLK_PLK1_PLK1_ST	Q3KR16	PLEKHG6	P53350	PLK1	S712	S707I	707	Missense	distal	-5	no	12.486	12.855	EPSD	COSMIC	10.919	Up-regulation
Other_PLK_PLK1_PLK1_ST	Q9H2D6	TRIOBP	P53350	PLK1	S245	Q242K	242	Missense	distal	-3	no	11.639	11.853	EPSD	COSMIC	10.919	Up-regulation
Other_PLK_PLK1_PLK1_ST	Q9H2D6	TRIOBP	P53350	PLK1	S294	R291S	291	Missense	distal	-3	no	11.684	10.852	EPSD	COSMIC	10.919	Loss
Other_PLK_PLK1_PLK1_ST	Q9H2D6	TRIOBP	P53350	PLK1	S294	R287S	287	Missense	distal	-7	no	11.684	12.181	EPSD	COSMIC	10.919	Up-regulation
Other_PLK_PLK1_PLK1_ST	Q9H2D6	TRIOBP	P53350	PLK1	S294	I299T	299	Missense	distal	5	no	11.684	10.781	EPSD	COSMIC	10.919	Loss
Other_PLK_PLK1_PLK1_ST	Q9H2D6	TRIOBP	P53350	PLK1	S294	S290P	290	Missense	distal	-4	no	11.684	11.562	EPSD	COSMIC	10.919	Down-regulation
Other_PLK_PLK1_PLK1_ST	Q9H2D6	TRIOBP	P53350	PLK1	S300	Q307H	307	Missense	distal	7	no	11.192	11.148	EPSD	COSMIC;GDSC;CCLE	10.919	Down-regulation
Other_PLK_PLK1_PLK1_ST	Q9H2D6	TRIOBP	P53350	PLK1	S300	I299T	299	Missense	proximal	-1	no	11.192	10.428	EPSD	COSMIC	10.919	Loss
Other_PLK_PLK1_PLK1_ST	Q9H2D6	TRIOBP	P53350	PLK1	S304	Q307H	307	Missense	distal	3	no	12.189	12.125	EPSD	COSMIC;GDSC;CCLE	10.919	Down-regulation
Other_PLK_PLK1_PLK1_ST	Q9H2D6	TRIOBP	P53350	PLK1	S304	T309I	309	Missense	distal	5	no	12.189	13.092	EPSD	COSMIC	10.919	Up-regulation
Other_PLK_PLK1_PLK1_ST	Q9H2D6	TRIOBP	P53350	PLK1	S304	I299T	299	Missense	distal	-5	no	12.189	12.036	EPSD	COSMIC	10.919	Down-regulation
Other_PLK_PLK1_PLK1_ST	Q9H2D6	TRIOBP	P53350	PLK1	S324	E327D	327	Missense	distal	3	no	11.428	11.493	EPSD	COSMIC	10.919	Up-regulation
Other_PLK_PLK1_PLK1_ST	Q9H2D6	TRIOBP	P53350	PLK1	S324	E327K	327	Missense	distal	3	no	11.428	11.222	EPSD	COSMIC	10.919	Down-regulation
Other_PLK_PLK1_PLK1_ST	Q9H2D6	TRIOBP	P53350	PLK1	S324	T319A	319	Missense	distal	-5	no	11.428	11.497	EPSD	COSMIC	10.919	Up-regulation
Other_PLK_PLK1_PLK1_ST	Q9H2D6	TRIOBP	P53350	PLK1	S324	P320S	320	Missense	distal	-4	no	11.428	11.550	EPSD	COSMIC	10.919	Up-regulation
Other_PLK_PLK1_PLK1_ST	Q9H2D6	TRIOBP	P53350	PLK1	S324	E317D	317	Missense	distal	-7	no	11.428	11.139	EPSD	COSMIC;GDSC	10.919	Down-regulation
Other_PLK_PLK1_PLK1_ST	Q9H2D6	TRIOBP	P53350	PLK1	S324	E317Q	317	Missense	distal	-7	no	11.428	11.392	EPSD	COSMIC	10.919	Down-regulation
Other_PLK_PLK1_PLK1_ST	Q9H2D6	TRIOBP	P53350	PLK1	S324	D318E	318	Missense	distal	-6	no	11.428	11.631	EPSD	COSMIC	10.919	Up-regulation
Other_PLK_PLK1_PLK1_ST	Q9H2D6	TRIOBP	P53350	PLK1	S324	P330S	330	Missense	distal	6	no	11.428	11.284	EPSD	COSMIC	10.919	Down-regulation
Other_PLK_PLK1_PLK1_ST	Q9H2D6	TRIOBP	P53350	PLK1	S324	T329P	329	Missense	distal	5	no	11.428	12.420	EPSD	COSMIC	10.919	Up-regulation
Other_PLK_PLK1_PLK1_ST	Q9H2D6	TRIOBP	P53350	PLK1	S324	T325P	325	Missense	proximal	1	no	11.428	11.957	EPSD	COSMIC	10.919	Up-regulation
Other_PLK_PLK1_PLK1_ST	Q9H2D6	TRIOBP	P53350	PLK1	S324	P330A	330	Missense	distal	6	no	11.428	11.567	EPSD	COSMIC	10.919	Up-regulation
Other_PLK_PLK1_PLK1_ST	Q9H2D6	TRIOBP	P53350	PLK1	T325	E327D	327	Missense	proximal	2	no	10.356	10.947	EPSD	COSMIC	10.919	Gain
Other_PLK_PLK1_PLK1_ST	Q9H2D6	TRIOBP	P53350	PLK1	S589	T594A	594	Missense	distal	5	no	10.497	11.668	EPSD	COSMIC	10.919	Gain
Other_PLK_PLK1_PLK1_ST	Q9H2D6	TRIOBP	P53350	PLK1	S638	P639F	639	Missense	proximal	1	no	10.671	12.598	EPSD	COSMIC	10.919	Gain
Other_PLK_PLK1_PLK1_ST	Q9H2D6	TRIOBP	P53350	PLK1	T714	P711L	711	Missense	distal	-3	no	9.856	11.048	EPSD	COSMIC	10.919	Gain
Other_PLK_PLK1_PLK1_ST	Q9H2D6	TRIOBP	P53350	PLK1	S856	N863I	863	Missense	distal	7	no	14.205	14.182	EPSD	COSMIC	10.919	Down-regulation
Other_PLK_PLK1_PLK1_ST	Q9H2D6	TRIOBP	P53350	PLK1	S856	Q860R	860	Missense	distal	4	no	14.205	13.676	EPSD	COSMIC	10.919	Down-regulation
Other_PLK_PLK1_PLK1_ST	Q9H2D6	TRIOBP	P53350	PLK1	S856	S858V	858	Missense	proximal	2	no	14.205	14.409	EPSD	COSMIC	10.919	Up-regulation
Other_PLK_PLK1_PLK1_ST	Q9H2D6	TRIOBP	P53350	PLK1	S1124	R1121W	1121	Missense	distal	-3	no	11.761	10.979	EPSD	COSMIC	10.919	Down-regulation
Other_PLK_PLK1_PLK1_ST	Q9H2D6	TRIOBP	P53350	PLK1	S1124	S1123F	1123	Missense	proximal	-1	no	11.761	11.222	EPSD	COSMIC	10.919	Down-regulation
Other_PLK_PLK1_PLK1_ST	Q9H2D6	TRIOBP	P53350	PLK1	S1133	L1139F	1139	Missense	distal	6	no	11.981	11.366	EPSD	COSMIC	10.919	Down-regulation
Other_PLK_PLK1_PLK1_ST	Q9H2D6	TRIOBP	P53350	PLK1	T1843	S1841Y	1841	Missense	proximal	-2	no	9.824	10.934	EPSD	COSMIC	10.919	Gain
Other_PLK_PLK1_PLK1_ST	Q9H2D6	TRIOBP	P53350	PLK1	S1949	P1956L	1956	Missense	distal	7	no	11.977	11.948	EPSD	COSMIC	10.919	Down-regulation
Other_PLK_PLK1_PLK1_ST	Q9H2D6	TRIOBP	P53350	PLK1	S2091	P2089L	2089	Missense	proximal	-2	no	11.860	11.496	EPSD	COSMIC	10.919	Down-regulation
Other_PLK_PLK1_PLK1_ST	Q9H2D6	TRIOBP	P53350	PLK1	S2175	L2170P	2170	Missense	distal	-5	no	12.179	11.778	EPSD	COSMIC	10.919	Down-regulation
Other_PLK_PLK1_PLK1_ST	Q9H2D6	TRIOBP	P53350	PLK1	T2229	T2229M	2229	Missense	central	0	yes	11.598	0.000	EPSD	COSMIC	10.919	Loss
Other_PLK_PLK1_PLK1_ST	Q9H2D6	TRIOBP	P53350	PLK1	T2229	E2227Q	2227	Missense	proximal	-2	no	11.598	8.939	EPSD	COSMIC	10.919	Loss
Other_PLK_PLK1_PLK1_ST	Q9H2D6	TRIOBP	P53350	PLK1	S2329	E2327D	2327	Missense	proximal	-2	no	12.366	12.760	EPSD	COSMIC	10.919	Up-regulation
Other_PLK_PLK1_PLK1_ST	Q9H2D6	TRIOBP	P53350	PLK1	S2358	R2360C	2360	Missense	proximal	2	no	11.157	10.912	EPSD	COSMIC	10.919	Loss
Other_PLK_PLK1_PLK1_ST	Q9H2D6	TRIOBP	P53350	PLK1	S2358	M2359K	2359	Missense	proximal	1	no	11.157	8.673	EPSD	COSMIC	10.919	Loss
Other_PLK_PLK1_PLK1_ST	Q9H2D6	TRIOBP	P53350	PLK1	S2358	A2351T	2351	Missense	distal	-7	no	11.157	11.502	EPSD	COSMIC	10.919	Up-regulation
Other_PLK_PLK1_PLK1_ST	Q9H2D6	TRIOBP	P53350	PLK1	S2362	R2360C	2360	Missense	proximal	-2	no	11.432	9.259	EPSD	COSMIC	10.919	Loss
Other_PLK_PLK1_PLK1_ST	Q9H2D6	TRIOBP	P53350	PLK1	S2362	M2359K	2359	Missense	distal	-3	no	11.432	11.552	EPSD	COSMIC	10.919	Up-regulation
Other_PLK_PLK1_PLK1_ST	Q00987	MDM2	P53350	PLK1	S172	E170D	170	Missense	proximal	-2	no	13.178	13.571	EPSD	COSMIC	10.919	Up-regulation
Other_PLK_PLK1_PLK1_ST	Q00987	MDM2	P53350	PLK1	S172	E178K	178	Missense	distal	6	no	13.178	13.108	EPSD	COSMIC	10.919	Down-regulation
Other_PLK_PLK1_PLK1_ST	Q00987	MDM2	P53350	PLK1	S172	S176F	176	Missense	distal	4	no	13.178	12.364	EPSD	COSMIC	10.919	Down-regulation
Other_PLK_PLK1_PLK1_ST	Q00987	MDM2	P53350	PLK1	S172	G177D	177	Missense	distal	5	no	13.178	13.144	EPSD	COSMIC	10.919	Down-regulation
Other_PLK_PLK1_PLK1_ST	Q00987	MDM2	P53350	PLK1	S172	R179P	179	Missense	distal	7	no	13.178	13.189	EPSD	COSMIC	10.919	Up-regulation
Other_PLK_PLK1_PLK1_ST	Q00987	MDM2	P53350	PLK1	S172	D173Y	173	Missense	proximal	1	no	13.178	12.980	EPSD	COSMIC	10.919	Down-regulation
Other_PLK_PLK1_PLK1_ST	Q00987	MDM2	P53350	PLK1	S172	S166C	166	Missense	distal	-6	no	13.178	11.975	EPSD	COSMIC	10.919	Down-regulation
Other_PLK_PLK1_PLK1_ST	Q00987	MDM2	P53350	PLK1	S172	E167Q	167	Missense	distal	-5	no	13.178	13.220	EPSD	COSMIC	10.919	Up-regulation
Other_PLK_PLK1_PLK1_ST	Q00987	MDM2	P53350	PLK1	S172	S166F	166	Missense	distal	-6	no	13.178	12.660	EPSD	COSMIC	10.919	Down-regulation
Other_PLK_PLK1_PLK1_ST	Q00987	MDM2	P53350	PLK1	S176	E170D	170	Missense	distal	-6	no	12.379	12.176	EPSD	COSMIC	10.919	Down-regulation
Other_PLK_PLK1_PLK1_ST	Q00987	MDM2	P53350	PLK1	S176	R183H	183	Missense	distal	7	no	12.379	12.349	EPSD	COSMIC	10.919	Down-regulation
Other_PLK_PLK1_PLK1_ST	Q00987	MDM2	P53350	PLK1	S176	E178K	178	Missense	proximal	2	no	12.379	12.210	EPSD	COSMIC	10.919	Down-regulation
Other_PLK_PLK1_PLK1_ST	Q00987	MDM2	P53350	PLK1	S176	S176F	176	Missense	central	0	yes	12.379	0.000	EPSD	COSMIC	10.919	Loss
Other_PLK_PLK1_PLK1_ST	Q00987	MDM2	P53350	PLK1	S176	G177D	177	Missense	proximal	1	no	12.379	12.377	EPSD	COSMIC	10.919	Down-regulation
Other_PLK_PLK1_PLK1_ST	Q00987	MDM2	P53350	PLK1	S176	R183C	183	Missense	distal	7	no	12.379	12.431	EPSD	COSMIC	10.919	Up-regulation
Other_PLK_PLK1_PLK1_ST	Q00987	MDM2	P53350	PLK1	S176	R179P	179	Missense	distal	3	no	12.379	12.524	EPSD	COSMIC	10.919	Up-regulation
Other_PLK_PLK1_PLK1_ST	Q00987	MDM2	P53350	PLK1	S176	D173Y	173	Missense	distal	-3	no	12.379	12.558	EPSD	COSMIC	10.919	Up-regulation
Other_PLK_PLK1_PLK1_ST	Q00987	MDM2	P53350	PLK1	S188	R183H	183	Missense	distal	-5	no	12.705	11.902	EPSD	COSMIC	10.919	Down-regulation
Other_PLK_PLK1_PLK1_ST	Q00987	MDM2	P53350	PLK1	S188	I189V	189	Missense	proximal	1	no	12.705	12.514	EPSD	COSMIC	10.919	Down-regulation
Other_PLK_PLK1_PLK1_ST	Q00987	MDM2	P53350	PLK1	S188	K185R	185	Missense	distal	-3	no	12.705	13.165	EPSD	COSMIC	10.919	Up-regulation
Other_PLK_PLK1_PLK1_ST	Q00987	MDM2	P53350	PLK1	S188	S190F	190	Missense	proximal	2	no	12.705	12.153	EPSD	COSMIC	10.919	Down-regulation
Other_PLK_PLK1_PLK1_ST	Q00987	MDM2	P53350	PLK1	S188	R183C	183	Missense	distal	-5	no	12.705	12.039	EPSD	COSMIC	10.919	Down-regulation
Other_PLK_PLK1_PLK1_ST	Q00987	MDM2	P53350	PLK1	S190	R183H	183	Missense	distal	-7	no	12.206	12.586	EPSD	COSMIC	10.919	Up-regulation
Other_PLK_PLK1_PLK1_ST	Q00987	MDM2	P53350	PLK1	S190	I189V	189	Missense	proximal	-1	no	12.206	11.232	EPSD	COSMIC	10.919	Down-regulation
Other_PLK_PLK1_PLK1_ST	Q00987	MDM2	P53350	PLK1	S190	K185R	185	Missense	distal	-5	no	12.206	12.744	EPSD	COSMIC	10.919	Up-regulation
Other_PLK_PLK1_PLK1_ST	Q00987	MDM2	P53350	PLK1	S190	S190F	190	Missense	central	0	yes	12.206	0.000	EPSD	COSMIC	10.919	Loss
Other_PLK_PLK1_PLK1_ST	Q00987	MDM2	P53350	PLK1	S190	R183C	183	Missense	distal	-7	no	12.206	12.086	EPSD	COSMIC	10.919	Down-regulation
Other_PLK_PLK1_PLK1_ST	Q00987	MDM2	P53350	PLK1	S190	S196F	196	Missense	distal	6	no	12.206	11.630	EPSD	COSMIC	10.919	Down-regulation
Other_PLK_PLK1_PLK1_ST	Q00987	MDM2	P53350	PLK1	S192	I189V	189	Missense	distal	-3	no	13.025	12.749	EPSD	COSMIC	10.919	Down-regulation
Other_PLK_PLK1_PLK1_ST	Q00987	MDM2	P53350	PLK1	S192	L199Q	199	Missense	distal	7	no	13.025	13.057	EPSD	COSMIC	10.919	Up-regulation
Other_PLK_PLK1_PLK1_ST	Q00987	MDM2	P53350	PLK1	S192	K185R	185	Missense	distal	-7	no	13.025	12.893	EPSD	COSMIC	10.919	Down-regulation
Other_PLK_PLK1_PLK1_ST	Q00987	MDM2	P53350	PLK1	S192	L199P	199	Missense	distal	7	no	13.025	13.054	EPSD	COSMIC	10.919	Up-regulation
Other_PLK_PLK1_PLK1_ST	Q00987	MDM2	P53350	PLK1	S192	S190F	190	Missense	proximal	-2	no	13.025	11.467	EPSD	COSMIC	10.919	Down-regulation
Other_PLK_PLK1_PLK1_ST	Q00987	MDM2	P53350	PLK1	S192	S196F	196	Missense	distal	4	no	13.025	12.211	EPSD	COSMIC	10.919	Down-regulation
Other_PLK_PLK1_PLK1_ST	Q00987	MDM2	P53350	PLK1	S196	I189V	189	Missense	distal	-7	no	13.657	13.822	EPSD	COSMIC	10.919	Up-regulation
Other_PLK_PLK1_PLK1_ST	Q00987	MDM2	P53350	PLK1	S196	L199Q	199	Missense	distal	3	no	13.657	13.876	EPSD	COSMIC	10.919	Up-regulation
Other_PLK_PLK1_PLK1_ST	Q00987	MDM2	P53350	PLK1	S196	L199P	199	Missense	distal	3	no	13.657	13.825	EPSD	COSMIC	10.919	Up-regulation
Other_PLK_PLK1_PLK1_ST	Q00987	MDM2	P53350	PLK1	S196	V201E	201	Missense	distal	5	no	13.657	13.537	EPSD	COSMIC	10.919	Down-regulation
Other_PLK_PLK1_PLK1_ST	Q00987	MDM2	P53350	PLK1	S196	S190F	190	Missense	distal	-6	no	13.657	13.140	EPSD	COSMIC	10.919	Down-regulation
Other_PLK_PLK1_PLK1_ST	Q00987	MDM2	P53350	PLK1	S196	S196F	196	Missense	central	0	yes	13.657	0.000	EPSD	COSMIC	10.919	Loss
Other_PLK_PLK1_PLK1_ST	Q00987	MDM2	P53350	PLK1	S260	L261R	261	Missense	proximal	1	no	14.954	11.823	PhosphoSitePlus	COSMIC	10.919	Down-regulation
Other_PLK_PLK1_PLK1_ST	Q00987	MDM2	P53350	PLK1	S260	E257K	257	Missense	distal	-3	no	14.954	15.494	PhosphoSitePlus	COSMIC	10.919	Up-regulation
Other_PLK_PLK1_PLK1_ST	Q00987	MDM2	P53350	PLK1	S260	S253Y	253	Missense	distal	-7	no	14.954	14.342	PhosphoSitePlus	COSMIC	10.919	Down-regulation
Other_PLK_PLK1_PLK1_ST	Q00987	MDM2	P53350	PLK1	S260	S262N	262	Missense	proximal	2	no	14.954	15.168	PhosphoSitePlus	COSMIC	10.919	Up-regulation
Other_PLK_PLK1_PLK1_ST	Q00987	MDM2	P53350	PLK1	S260	D255N	255	Missense	distal	-5	no	14.954	14.658	PhosphoSitePlus	COSMIC	10.919	Down-regulation
Other_PLK_PLK1_PLK1_ST	Q00987	MDM2	P53350	PLK1	S260	L254V	254	Missense	distal	-6	no	14.954	15.014	PhosphoSitePlus	COSMIC	10.919	Up-regulation
Other_PLK_PLK1_PLK1_ST	Q00987	MDM2	P53350	PLK1	S260	G265E	265	Missense	distal	5	no	14.954	14.480	PhosphoSitePlus	COSMIC	10.919	Down-regulation
Other_PLK_PLK1_PLK1_ST	Q00987	MDM2	P53350	PLK1	S260	E263K	263	Missense	distal	3	no	14.954	14.748	PhosphoSitePlus	COSMIC	10.919	Down-regulation
Other_PLK_PLK1_PLK1_ST	Q00987	MDM2	P53350	PLK1	S290	G284W	284	Missense	distal	-6	no	12.326	11.968	EPSD	COSMIC	10.919	Down-regulation
Other_PLK_PLK1_PLK1_ST	Q00987	MDM2	P53350	PLK1	S290	A283T	283	Missense	distal	-7	no	12.326	12.671	EPSD	COSMIC	10.919	Up-regulation
Other_PLK_PLK1_PLK1_ST	Q00987	MDM2	P53350	PLK1	S290	E285K	285	Missense	distal	-5	no	12.326	12.570	EPSD	COSMIC	10.919	Up-regulation
Other_PLK_PLK1_PLK1_ST	Q00987	MDM2	P53350	PLK1	S290	E296D	296	Missense	distal	6	no	12.326	12.476	EPSD	COSMIC	10.919	Up-regulation
Other_PLK_PLK1_PLK1_ST	Q00987	MDM2	P53350	PLK1	S290	D294Y	294	Missense	distal	4	no	12.326	12.080	EPSD	COSMIC	10.919	Down-regulation
Other_PLK_PLK1_PLK1_ST	Q00987	MDM2	P53350	PLK1	S290	D287N	287	Missense	distal	-3	no	12.326	12.226	EPSD	COSMIC	10.919	Down-regulation
Other_PLK_PLK1_PLK1_ST	Q00987	MDM2	P53350	PLK1	S290	F291S	291	Missense	proximal	1	no	12.326	9.278	EPSD	COSMIC	10.919	Loss
Other_PLK_PLK1_PLK1_ST	Q00987	MDM2	P53350	PLK1	S290	E292K	292	Missense	proximal	2	no	12.326	12.157	EPSD	COSMIC	10.919	Down-regulation
Other_PLK_PLK1_PLK1_ST	Q00987	MDM2	P53350	PLK1	S290	I297M	297	Missense	distal	7	no	12.326	12.362	EPSD	COSMIC	10.919	Up-regulation
Other_PLK_PLK1_PLK1_ST	Q00987	MDM2	P53350	PLK1	S342	E340D	340	Missense	proximal	-2	no	11.992	12.386	EPSD	COSMIC	10.919	Up-regulation
Other_PLK_PLK1_PLK1_ST	Q00987	MDM2	P53350	PLK1	S342	D337N	337	Missense	distal	-5	no	11.992	11.696	EPSD	COSMIC	10.919	Down-regulation
Other_PLK_PLK1_PLK1_ST	Q00987	MDM2	P53350	PLK1	S350	G356S	356	Missense	distal	6	no	11.815	12.019	EPSD	COSMIC	10.919	Up-regulation
Other_PLK_PLK1_PLK1_ST	Q00987	MDM2	P53350	PLK1	S350	E355Q	355	Missense	distal	5	no	11.815	11.656	EPSD	COSMIC	10.919	Down-regulation
Other_PLK_PLK1_PLK1_ST	Q00987	MDM2	P53350	PLK1	S350	E354K	354	Missense	distal	4	no	11.815	11.442	EPSD	COSMIC	10.919	Down-regulation
Other_PLK_PLK1_PLK1_ST	Q00987	MDM2	P53350	PLK1	S350	E355K	355	Missense	distal	5	no	11.815	11.826	EPSD	COSMIC	10.919	Up-regulation
Other_PLK_PLK1_PLK1_ST	Q00987	MDM2	P53350	PLK1	S388	Q384R	384	Missense	distal	-4	no	10.949	10.661	EPSD	COSMIC	10.919	Loss
Other_PLK_PLK1_PLK1_ST	Q00987	MDM2	P53350	PLK1	S388	D393E	393	Missense	distal	5	no	10.949	10.508	EPSD	COSMIC	10.919	Loss
Other_PLK_PLK1_PLK1_ST	Q00987	MDM2	P53350	PLK1	S388	D393H	393	Missense	distal	5	no	10.949	10.494	EPSD	COSMIC	10.919	Loss
Other_PLK_PLK1_PLK1_ST	Q00987	MDM2	P53350	PLK1	S388	A385V	385	Missense	distal	-3	no	10.949	10.550	EPSD	COSMIC	10.919	Loss
Other_PLK_PLK1_PLK1_ST	Q00987	MDM2	P53350	PLK1	S406	S407G	407	Missense	proximal	1	no	10.773	11.710	EPSD	COSMIC	10.919	Gain
Other_PLK_PLK1_PLK1_ST	Q00987	MDM2	P53350	PLK1	S406	S407N	407	Missense	proximal	1	no	10.773	11.513	EPSD	COSMIC	10.919	Gain
Other_PLK_PLK1_PLK1_ST	Q00987	MDM2	P53350	PLK1	S425	T419I	419	Missense	distal	-6	no	11.011	11.183	EPSD	COSMIC	10.919	Up-regulation
Other_PLK_PLK1_PLK1_ST	Q00987	MDM2	P53350	PLK1	S425	S425C	425	Missense	central	0	yes	11.011	0.000	EPSD	COSMIC	10.919	Loss
Other_PLK_PLK1_PLK1_ST	Q00987	MDM2	P53350	PLK1	S425	S429R	429	Missense	distal	4	no	11.011	10.066	EPSD	COSMIC	10.919	Loss
Other_PLK_PLK1_PLK1_ST	Q00987	MDM2	P53350	PLK1	S425	V426A	426	Missense	proximal	1	no	11.011	9.573	EPSD	COSMIC	10.919	Loss
Other_PLK_PLK1_PLK1_ST	Q00987	MDM2	P53350	PLK1	S429	A434V	434	Missense	distal	5	no	12.323	11.585	EPSD	COSMIC	10.919	Down-regulation
Other_PLK_PLK1_PLK1_ST	Q00987	MDM2	P53350	PLK1	S429	S425C	425	Missense	distal	-4	no	12.323	11.511	EPSD	COSMIC	10.919	Down-regulation
Other_PLK_PLK1_PLK1_ST	Q00987	MDM2	P53350	PLK1	S429	E436G	436	Missense	distal	7	no	12.323	12.345	EPSD	COSMIC	10.919	Up-regulation
Other_PLK_PLK1_PLK1_ST	Q00987	MDM2	P53350	PLK1	S429	S429R	429	Missense	central	0	yes	12.323	0.000	EPSD	COSMIC	10.919	Loss
Other_PLK_PLK1_PLK1_ST	Q00987	MDM2	P53350	PLK1	S429	V426A	426	Missense	distal	-3	no	12.323	12.722	EPSD	COSMIC	10.919	Up-regulation
Other_PLK_PLK1_PLK1_ST	Q9H6R7	WDCP	P53350	PLK1	S259	G255C	255	Missense	distal	-4	no	11.395	11.237	EPSD	COSMIC	10.919	Down-regulation
Other_PLK_PLK1_PLK1_ST	Q9H6R7	WDCP	P53350	PLK1	S259	V253G	253	Missense	distal	-6	no	11.395	11.124	EPSD	COSMIC	10.919	Down-regulation
Other_PLK_PLK1_PLK1_ST	Q9H6R7	WDCP	P53350	PLK1	S259	S259C	259	Missense	central	0	yes	11.395	0.000	EPSD	COSMIC	10.919	Loss
Other_PLK_PLK1_PLK1_ST	Q9H6R7	WDCP	P53350	PLK1	S259	P252Q	252	Missense	distal	-7	no	11.395	11.509	EPSD	COSMIC	10.919	Up-regulation
Other_PLK_PLK1_PLK1_ST	Q9H6R7	WDCP	P53350	PLK1	S259	R258H	258	Missense	proximal	-1	no	11.395	12.393	EPSD	COSMIC	10.919	Up-regulation
Other_PLK_PLK1_PLK1_ST	Q9H6R7	WDCP	P53350	PLK1	T265	R258H	258	Missense	distal	-7	no	10.552	10.931	EPSD	COSMIC	10.919	Gain
Other_PLK_PLK1_PLK1_ST	Q9H6R7	WDCP	P53350	PLK1	S317	L321F	321	Missense	distal	4	no	13.827	13.626	EPSD	COSMIC	10.919	Down-regulation
Other_PLK_PLK1_PLK1_ST	Q9H6R7	WDCP	P53350	PLK1	S358	I364V	364	Missense	distal	6	no	11.071	11.178	EPSD	COSMIC	10.919	Up-regulation
Other_PLK_PLK1_PLK1_ST	Q9H6R7	WDCP	P53350	PLK1	S358	I363M	363	Missense	distal	5	no	11.071	10.870	EPSD	COSMIC;GDSC	10.919	Loss
Other_PLK_PLK1_PLK1_ST	Q9H6R7	WDCP	P53350	PLK1	S358	L365S	365	Missense	distal	7	no	11.071	11.073	EPSD	COSMIC	10.919	Up-regulation
Other_PLK_PLK1_PLK1_ST	Q9H6R7	WDCP	P53350	PLK1	S358	V353I	353	Missense	distal	-5	no	11.071	11.229	EPSD	COSMIC	10.919	Up-regulation
Other_PLK_PLK1_PLK1_ST	Q9H6R7	WDCP	P53350	PLK1	S358	C361S	361	Missense	distal	3	no	11.071	11.136	EPSD	COSMIC	10.919	Up-regulation
Other_PLK_PLK1_PLK1_ST	Q9H6R7	WDCP	P53350	PLK1	S368	I364V	364	Missense	distal	-4	no	14.164	14.029	EPSD	COSMIC	10.919	Down-regulation
Other_PLK_PLK1_PLK1_ST	Q9H6R7	WDCP	P53350	PLK1	S368	I363M	363	Missense	distal	-5	no	14.164	13.859	EPSD	COSMIC;GDSC	10.919	Down-regulation
Other_PLK_PLK1_PLK1_ST	Q9H6R7	WDCP	P53350	PLK1	S368	L365S	365	Missense	distal	-3	no	14.164	13.389	EPSD	COSMIC	10.919	Down-regulation
Other_PLK_PLK1_PLK1_ST	Q9H6R7	WDCP	P53350	PLK1	S368	I366M	366	Missense	proximal	-2	no	14.164	14.271	EPSD	COSMIC	10.919	Up-regulation
Other_PLK_PLK1_PLK1_ST	Q9H6R7	WDCP	P53350	PLK1	S368	P371S	371	Missense	distal	3	no	14.164	14.142	EPSD	COSMIC	10.919	Down-regulation
Other_PLK_PLK1_PLK1_ST	Q9H6R7	WDCP	P53350	PLK1	S368	C361S	361	Missense	distal	-7	no	14.164	14.781	EPSD	COSMIC	10.919	Up-regulation
Other_PLK_PLK1_PLK1_ST	Q9H6R7	WDCP	P53350	PLK1	S372	P371S	371	Missense	proximal	-1	no	10.201	11.375	EPSD	COSMIC	10.919	Gain
Other_PLK_PLK1_PLK1_ST	Q9H6R7	WDCP	P53350	PLK1	S466	S466R	466	Missense	central	0	yes	11.148	0.000	EPSD	COSMIC	10.919	Loss
Other_PLK_PLK1_PLK1_ST	Q9H6R7	WDCP	P53350	PLK1	S466	N459K	459	Missense	distal	-7	no	11.148	10.993	EPSD	COSMIC	10.919	Down-regulation
Other_PLK_PLK1_PLK1_ST	Q9H6R7	WDCP	P53350	PLK1	S466	R460I	460	Missense	distal	-6	no	11.148	11.665	EPSD	COSMIC	10.919	Up-regulation
Other_PLK_PLK1_PLK1_ST	Q9H6R7	WDCP	P53350	PLK1	S510	I511V	511	Missense	proximal	1	no	13.839	13.648	EPSD	COSMIC	10.919	Down-regulation
Other_PLK_PLK1_PLK1_ST	Q9H6R7	WDCP	P53350	PLK1	S686	D681E	681	Missense	distal	-5	no	11.453	11.111	EPSD;PhosphoSitePlus	COSMIC	10.919	Down-regulation
Other_PLK_PLK1_PLK1_ST	Q9H6R7	WDCP	P53350	PLK1	S686	S686C	686	Missense	central	0	yes	11.453	0.000	EPSD;PhosphoSitePlus	COSMIC	10.919	Loss
Other_PLK_PLK1_PLK1_ST	Q9H6R7	WDCP	P53350	PLK1	S686	A693V	693	Missense	distal	7	no	11.453	11.476	EPSD;PhosphoSitePlus	COSMIC;GDSC	10.919	Up-regulation
Other_PLK_PLK1_PLK1_ST	Q9H6R7	WDCP	P53350	PLK1	S695	S696Y	696	Missense	proximal	1	no	10.430	11.168	PhosphoSitePlus;EPSD	COSMIC	10.919	Gain
Other_PLK_PLK1_PLK1_ST	Q9H6R7	WDCP	P53350	PLK1	S696	S696Y	696	Missense	central	0	yes	11.831	0.000	EPSD	COSMIC	10.919	Loss
Other_PLK_PLK1_PLK1_ST	Q9H6R7	WDCP	P53350	PLK1	S696	A693V	693	Missense	distal	-3	no	11.831	11.432	EPSD	COSMIC;GDSC	10.919	Down-regulation
Other_PLK_PLK1_PLK1_ST	O60260	PRKN	P53350	PLK1	S108	D106N	106	Missense	proximal	-2	no	12.200	10.957	EPSD	COSMIC	10.919	Down-regulation
Other_PLK_PLK1_PLK1_ST	O60260	PRKN	P53350	PLK1	S108	D115N	115	Missense	distal	7	no	12.200	12.281	EPSD	COSMIC	10.919	Up-regulation
Other_PLK_PLK1_PLK1_ST	O60260	PRKN	P53350	PLK1	S108	L107F	107	Missense	proximal	-1	no	12.200	12.120	EPSD	COSMIC;GDSC	10.919	Down-regulation
Other_PLK_PLK1_PLK1_ST	O60260	PRKN	P53350	PLK1	S108	S108N	108	Missense	central	0	yes	12.200	0.000	EPSD	COSMIC	10.919	Loss
Other_PLK_PLK1_PLK1_ST	O60260	PRKN	P53350	PLK1	S108	P113S	113	Missense	distal	5	no	12.200	11.812	EPSD	COSMIC	10.919	Down-regulation
Other_PLK_PLK1_PLK1_ST	O60260	PRKN	P53350	PLK1	S108	R104W	104	Missense	distal	-4	no	12.200	12.614	EPSD	COSMIC	10.919	Up-regulation
Other_PLK_PLK1_PLK1_ST	O60260	PRKN	P53350	PLK1	S108	S110T	110	Missense	proximal	2	no	12.200	11.559	EPSD	COSMIC	10.919	Down-regulation
Other_PLK_PLK1_PLK1_ST	O60260	PRKN	P53350	PLK1	S108	R104Q	104	Missense	distal	-4	no	12.200	12.488	EPSD	COSMIC;GDSC	10.919	Up-regulation
Other_PLK_PLK1_PLK1_ST	O60260	PRKN	P53350	PLK1	S108	V105G	105	Missense	distal	-3	no	12.200	12.848	EPSD	COSMIC	10.919	Up-regulation
Other_PLK_PLK1_PLK1_ST	O60260	PRKN	P53350	PLK1	S108	L112I	112	Missense	distal	4	no	12.200	11.620	EPSD	COSMIC	10.919	Down-regulation
Other_PLK_PLK1_PLK1_ST	O60260	PRKN	P53350	PLK1	S131	K129N	129	Missense	proximal	-2	no	10.822	12.851	EPSD	COSMIC	10.919	Gain
Other_PLK_PLK1_PLK1_ST	O60260	PRKN	P53350	PLK1	S131	K129M	129	Missense	proximal	-2	no	10.822	10.985	EPSD	COSMIC	10.919	Gain
Other_PLK_PLK1_PLK1_ST	O60260	PRKN	P53350	PLK1	S131	T125S	125	Missense	distal	-6	no	10.822	10.925	EPSD	COSMIC	10.919	Gain
Other_PLK_PLK1_PLK1_ST	O60260	PRKN	P53350	PLK1	S378	A379V	379	Missense	proximal	1	no	9.703	11.141	PhosphoSitePlus	COSMIC	10.919	Gain
Other_PLK_PLK1_PLK1_ST	Q00839	HNRNPU	P53350	PLK1	T474	P480A	480	Missense	distal	6	no	13.648	13.787	EPSD	COSMIC;CCLE	10.919	Up-regulation
Other_PLK_PLK1_PLK1_ST	Q00839	HNRNPU	P53350	PLK1	T474	P468L	468	Missense	distal	-6	no	13.648	13.937	EPSD	COSMIC	10.919	Up-regulation
Other_PLK_PLK1_PLK1_ST	Q00839	HNRNPU	P53350	PLK1	T582	A588V	588	Missense	distal	6	no	11.635	11.460	EPSD	COSMIC	10.919	Down-regulation
Other_PLK_PLK1_PLK1_ST	Q00839	HNRNPU	P53350	PLK1	T582	V584L	584	Missense	proximal	2	no	11.635	11.503	EPSD	COSMIC	10.919	Down-regulation
Other_PLK_PLK1_PLK1_ST	Q9NS56	TOPORS	P53350	PLK1	S65	R59S	59	Missense	distal	-6	no	11.259	11.706	EPSD	COSMIC	10.919	Up-regulation
Other_PLK_PLK1_PLK1_ST	Q9NS56	TOPORS	P53350	PLK1	S65	A63T	63	Missense	proximal	-2	no	11.259	10.640	EPSD	COSMIC	10.919	Loss
Other_PLK_PLK1_PLK1_ST	Q9NS56	TOPORS	P53350	PLK1	S98	S101L	101	Missense	distal	3	no	11.935	11.788	EPSD	COSMIC	10.919	Down-regulation
Other_PLK_PLK1_PLK1_ST	Q9NS56	TOPORS	P53350	PLK1	S98	A95D	95	Missense	distal	-3	no	11.935	11.702	EPSD	COSMIC	10.919	Down-regulation
Other_PLK_PLK1_PLK1_ST	Q9NS56	TOPORS	P53350	PLK1	S98	I105V	105	Missense	distal	7	no	11.935	11.951	EPSD	COSMIC	10.919	Up-regulation
Other_PLK_PLK1_PLK1_ST	Q9NS56	TOPORS	P53350	PLK1	S114	R118C	118	Missense	distal	4	no	10.507	10.925	EPSD	COSMIC	10.919	Gain
Other_PLK_PLK1_PLK1_ST	Q9NS56	TOPORS	P53350	PLK1	S170	R177Q	177	Missense	distal	7	no	12.195	12.210	EPSD	COSMIC	10.919	Up-regulation
Other_PLK_PLK1_PLK1_ST	Q9NS56	TOPORS	P53350	PLK1	S170	S170Y	170	Missense	central	0	yes	12.195	0.000	EPSD	COSMIC	10.919	Loss
Other_PLK_PLK1_PLK1_ST	Q9NS56	TOPORS	P53350	PLK1	S170	S166L	166	Missense	distal	-4	no	12.195	12.002	EPSD	COSMIC	10.919	Down-regulation
Other_PLK_PLK1_PLK1_ST	Q9NS56	TOPORS	P53350	PLK1	S191	T185K	185	Missense	distal	-6	no	12.463	12.111	EPSD	COSMIC	10.919	Down-regulation
Other_PLK_PLK1_PLK1_ST	Q9NS56	TOPORS	P53350	PLK1	S498	S501Y	501	Missense	distal	3	no	11.379	11.199	EPSD	COSMIC	10.919	Down-regulation
Other_PLK_PLK1_PLK1_ST	Q9NS56	TOPORS	P53350	PLK1	S577	S577F	577	Missense	central	0	yes	13.379	0.000	EPSD	COSMIC	10.919	Loss
Other_PLK_PLK1_PLK1_ST	Q9NS56	TOPORS	P53350	PLK1	T659	R655S	655	Missense	distal	-4	no	10.493	11.060	EPSD	COSMIC	10.919	Gain
Other_PLK_PLK1_PLK1_ST	Q9NS56	TOPORS	P53350	PLK1	S664	R669T	669	Missense	distal	5	no	11.666	10.716	EPSD	COSMIC	10.919	Loss
Other_PLK_PLK1_PLK1_ST	Q9NS56	TOPORS	P53350	PLK1	S664	S666N	666	Missense	proximal	2	no	11.666	11.879	EPSD	COSMIC	10.919	Up-regulation
Other_PLK_PLK1_PLK1_ST	Q9NS56	TOPORS	P53350	PLK1	T842	S846C	846	Missense	distal	4	no	12.391	11.865	EPSD	COSMIC	10.919	Down-regulation
Other_PLK_PLK1_PLK1_ST	Q9NS56	TOPORS	P53350	PLK1	S866	R863W	863	Missense	distal	-3	no	11.044	10.263	EPSD	COSMIC;GDSC;CCLE	10.919	Loss
Other_PLK_PLK1_PLK1_ST	Q9NS56	TOPORS	P53350	PLK1	S866	K861N	861	Missense	distal	-5	no	11.044	10.846	EPSD	COSMIC	10.919	Loss
Other_PLK_PLK1_PLK1_ST	Q9NS56	TOPORS	P53350	PLK1	S866	T862S	862	Missense	distal	-4	no	11.044	11.406	EPSD	COSMIC;GDSC;CCLE	10.919	Up-regulation
Other_PLK_PLK1_PLK1_ST	Q9NS56	TOPORS	P53350	PLK1	S914	E919D	919	Missense	distal	5	no	11.879	12.320	EPSD	COSMIC;GDSC;CCLE	10.919	Up-regulation
Other_PLK_PLK1_PLK1_ST	Q9NS56	TOPORS	P53350	PLK1	S914	V920L	920	Missense	distal	6	no	11.879	11.811	EPSD	COSMIC	10.919	Down-regulation
Other_PLK_PLK1_PLK1_ST	Q9NS56	TOPORS	P53350	PLK1	S918	E919D	919	Missense	proximal	1	no	11.532	11.776	EPSD	COSMIC;GDSC;CCLE	10.919	Up-regulation
Other_PLK_PLK1_PLK1_ST	Q9NS56	TOPORS	P53350	PLK1	S918	V920L	920	Missense	proximal	2	no	11.532	11.400	EPSD	COSMIC	10.919	Down-regulation
Other_PLK_PLK1_PLK1_ST	Q9NS56	TOPORS	P53350	PLK1	S1017	S1013G	1013	Missense	distal	-4	no	12.143	11.489	EPSD	COSMIC	10.919	Down-regulation
Other_PLK_PLK1_PLK1_ST	Q9NS56	TOPORS	P53350	PLK1	S1032	R1030Q	1030	Missense	proximal	-2	no	12.908	12.733	EPSD	COSMIC	10.919	Down-regulation
Other_PLK_PLK1_PLK1_ST	P35222	CTNNB1	P53350	PLK1	S23	A21D	21	Missense	proximal	-2	no	8.591	11.162	EPSD	COSMIC	10.919	Gain
Other_PLK_PLK1_PLK1_ST	P35222	CTNNB1	P53350	PLK1	S29	I35T	35	Missense	distal	6	no	11.718	11.992	EPSD	COSMIC	10.919	Up-regulation
Other_PLK_PLK1_PLK1_ST	P35222	CTNNB1	P53350	PLK1	S29	Q28E	28	Missense	proximal	-1	no	11.718	12.047	EPSD	COSMIC	10.919	Up-regulation
Other_PLK_PLK1_PLK1_ST	P35222	CTNNB1	P53350	PLK1	S29	D32E	32	Missense	distal	3	no	11.718	11.652	EPSD	COSMIC	10.919	Down-regulation
Other_PLK_PLK1_PLK1_ST	P35222	CTNNB1	P53350	PLK1	S29	H36R	36	Missense	distal	7	no	11.718	11.748	EPSD	COSMIC	10.919	Up-regulation
Other_PLK_PLK1_PLK1_ST	P35222	CTNNB1	P53350	PLK1	S29	G34L	34	Missense	distal	5	no	11.718	11.189	EPSD	COSMIC	10.919	Down-regulation
Other_PLK_PLK1_PLK1_ST	P35222	CTNNB1	P53350	PLK1	S29	V22I	22	Missense	distal	-7	no	11.718	11.553	EPSD	COSMIC	10.919	Down-regulation
Other_PLK_PLK1_PLK1_ST	P35222	CTNNB1	P53350	PLK1	S29	S33L	33	Missense	distal	4	no	11.718	11.106	EPSD	COSMIC;CCLE	10.919	Down-regulation
Other_PLK_PLK1_PLK1_ST	P35222	CTNNB1	P53350	PLK1	S29	S29P	29	Missense	central	0	yes	11.718	0.000	EPSD	COSMIC	10.919	Loss
Other_PLK_PLK1_PLK1_ST	P35222	CTNNB1	P53350	PLK1	S29	L31P	31	Missense	proximal	2	no	11.718	10.170	EPSD	COSMIC	10.919	Loss
Other_PLK_PLK1_PLK1_ST	P35222	CTNNB1	P53350	PLK1	S29	Q27H	27	Missense	proximal	-2	no	11.718	11.584	EPSD	COSMIC	10.919	Down-regulation
Other_PLK_PLK1_PLK1_ST	P35222	CTNNB1	P53350	PLK1	S29	S33N	33	Missense	distal	4	no	11.718	11.482	EPSD	COSMIC	10.919	Down-regulation
Other_PLK_PLK1_PLK1_ST	P35222	CTNNB1	P53350	PLK1	S29	H36Y	36	Missense	distal	7	no	11.718	11.787	EPSD	COSMIC	10.919	Up-regulation
Other_PLK_PLK1_PLK1_ST	P35222	CTNNB1	P53350	PLK1	S29	S23N	23	Missense	distal	-6	no	11.718	11.521	EPSD	COSMIC	10.919	Down-regulation
Other_PLK_PLK1_PLK1_ST	P35222	CTNNB1	P53350	PLK1	S29	S29F	29	Missense	central	0	yes	11.718	0.000	EPSD	COSMIC	10.919	Loss
Other_PLK_PLK1_PLK1_ST	P35222	CTNNB1	P53350	PLK1	S29	Y30C	30	Missense	proximal	1	no	11.718	11.215	EPSD	COSMIC	10.919	Down-regulation
Other_PLK_PLK1_PLK1_ST	P35222	CTNNB1	P53350	PLK1	S29	S29Y	29	Missense	central	0	yes	11.718	0.000	EPSD	COSMIC	10.919	Loss
Other_PLK_PLK1_PLK1_ST	P35222	CTNNB1	P53350	PLK1	S29	S23R	23	Missense	distal	-6	no	11.718	11.270	EPSD	COSMIC	10.919	Down-regulation
Other_PLK_PLK1_PLK1_ST	P35222	CTNNB1	P53350	PLK1	S29	H24Y	24	Missense	distal	-5	no	11.718	11.935	EPSD	COSMIC	10.919	Up-regulation
Other_PLK_PLK1_PLK1_ST	P35222	CTNNB1	P53350	PLK1	S29	W25R	25	Missense	distal	-4	no	11.718	11.303	EPSD	COSMIC	10.919	Down-regulation
Other_PLK_PLK1_PLK1_ST	P35222	CTNNB1	P53350	PLK1	S29	V22A	22	Missense	distal	-7	no	11.718	11.661	EPSD	COSMIC	10.919	Down-regulation
Other_PLK_PLK1_PLK1_ST	P35222	CTNNB1	P53350	PLK1	S29	I35M	35	Missense	distal	6	no	11.718	11.462	EPSD	COSMIC	10.919	Down-regulation
Other_PLK_PLK1_PLK1_ST	P35222	CTNNB1	P53350	PLK1	S29	W25L	25	Missense	distal	-4	no	11.718	11.676	EPSD	COSMIC	10.919	Down-regulation
Other_PLK_PLK1_PLK1_ST	P35222	CTNNB1	P53350	PLK1	S29	H24Q	24	Missense	distal	-5	no	11.718	11.781	EPSD	COSMIC	10.919	Up-regulation
Other_PLK_PLK1_PLK1_ST	P35222	CTNNB1	P53350	PLK1	S29	S23G	23	Missense	distal	-6	no	11.718	11.172	EPSD	COSMIC	10.919	Down-regulation
Other_PLK_PLK1_PLK1_ST	P35222	CTNNB1	P53350	PLK1	S29	V22G	22	Missense	distal	-7	no	11.718	11.318	EPSD	COSMIC	10.919	Down-regulation
Other_PLK_PLK1_PLK1_ST	P35222	CTNNB1	P53350	PLK1	S29	S29A	29	Missense	central	0	yes	11.718	0.000	EPSD	COSMIC	10.919	Loss
Other_PLK_PLK1_PLK1_ST	P35222	CTNNB1	P53350	PLK1	S29	G34A	34	Missense	distal	5	no	11.718	12.102	EPSD	COSMIC	10.919	Up-regulation
Other_PLK_PLK1_PLK1_ST	P35222	CTNNB1	P53350	PLK1	S29	L31W	31	Missense	proximal	2	no	11.718	11.665	EPSD	COSMIC	10.919	Down-regulation
Other_PLK_PLK1_PLK1_ST	P35222	CTNNB1	P53350	PLK1	S29	G34I	34	Missense	distal	5	no	11.718	11.833	EPSD	COSMIC	10.919	Up-regulation
Other_PLK_PLK1_PLK1_ST	P35222	CTNNB1	P53350	PLK1	S29	I35N	35	Missense	distal	6	no	11.718	11.767	EPSD	COSMIC	10.919	Up-regulation
Other_PLK_PLK1_PLK1_ST	P35222	CTNNB1	P53350	PLK1	S29	D32C	32	Missense	distal	3	no	11.718	11.408	EPSD	COSMIC	10.919	Down-regulation
Other_PLK_PLK1_PLK1_ST	P35222	CTNNB1	P53350	PLK1	S29	Y30S	30	Missense	proximal	1	no	11.718	10.980	EPSD	COSMIC	10.919	Down-regulation
Other_PLK_PLK1_PLK1_ST	P35222	CTNNB1	P53350	PLK1	S29	L31M	31	Missense	proximal	2	no	11.718	11.644	EPSD	COSMIC	10.919	Down-regulation
Other_PLK_PLK1_PLK1_ST	P35222	CTNNB1	P53350	PLK1	S29	H24R	24	Missense	distal	-5	no	11.718	12.521	EPSD	COSMIC	10.919	Up-regulation
Other_PLK_PLK1_PLK1_ST	P35222	CTNNB1	P53350	PLK1	S29	L31Q	31	Missense	proximal	2	no	11.718	11.244	EPSD	COSMIC	10.919	Down-regulation
Other_PLK_PLK1_PLK1_ST	P35222	CTNNB1	P53350	PLK1	S29	G34D	34	Missense	distal	5	no	11.718	11.684	EPSD	COSMIC	10.919	Down-regulation
Other_PLK_PLK1_PLK1_ST	P35222	CTNNB1	P53350	PLK1	S29	Q26R	26	Missense	distal	-3	no	11.718	12.393	EPSD	COSMIC;GDSC;CCLE	10.919	Up-regulation
Other_PLK_PLK1_PLK1_ST	P35222	CTNNB1	P53350	PLK1	S29	I35K	35	Missense	distal	6	no	11.718	11.769	EPSD	COSMIC	10.919	Up-regulation
Other_PLK_PLK1_PLK1_ST	P35222	CTNNB1	P53350	PLK1	S29	Q28R	28	Missense	proximal	-1	no	11.718	11.114	EPSD	COSMIC	10.919	Down-regulation
Other_PLK_PLK1_PLK1_ST	P35222	CTNNB1	P53350	PLK1	S29	D32F	32	Missense	distal	3	no	11.718	11.532	EPSD	COSMIC	10.919	Down-regulation
Other_PLK_PLK1_PLK1_ST	P35222	CTNNB1	P53350	PLK1	S29	D32X	32	Missense	distal	3	no	11.718	11.311	EPSD	COSMIC	10.919	Down-regulation
Other_PLK_PLK1_PLK1_ST	P35222	CTNNB1	P53350	PLK1	S29	S33K	33	Missense	distal	4	no	11.718	11.333	EPSD	COSMIC	10.919	Down-regulation
Other_PLK_PLK1_PLK1_ST	P35222	CTNNB1	P53350	PLK1	S29	I35V	35	Missense	distal	6	no	11.718	11.824	EPSD	COSMIC	10.919	Up-regulation
Other_PLK_PLK1_PLK1_ST	P35222	CTNNB1	P53350	PLK1	S29	G34C	34	Missense	distal	5	no	11.718	11.664	EPSD	COSMIC	10.919	Down-regulation
Other_PLK_PLK1_PLK1_ST	P35222	CTNNB1	P53350	PLK1	S29	I35F	35	Missense	distal	6	no	11.718	11.140	EPSD	COSMIC	10.919	Down-regulation
Other_PLK_PLK1_PLK1_ST	P35222	CTNNB1	P53350	PLK1	S33	A39G	39	Missense	distal	6	no	11.011	10.524	EPSD	COSMIC	10.919	Loss
Other_PLK_PLK1_PLK1_ST	P35222	CTNNB1	P53350	PLK1	S33	G38A	38	Missense	distal	5	no	11.011	11.395	EPSD	COSMIC	10.919	Up-regulation
Other_PLK_PLK1_PLK1_ST	P35222	CTNNB1	P53350	PLK1	S33	T40I	40	Missense	distal	7	no	11.011	11.058	EPSD	COSMIC	10.919	Up-regulation
Other_PLK_PLK1_PLK1_ST	P35222	CTNNB1	P53350	PLK1	S33	I35T	35	Missense	proximal	2	no	11.011	9.949	EPSD	COSMIC	10.919	Loss
Other_PLK_PLK1_PLK1_ST	P35222	CTNNB1	P53350	PLK1	S33	Q28E	28	Missense	distal	-5	no	11.011	10.968	EPSD	COSMIC	10.919	Down-regulation
Other_PLK_PLK1_PLK1_ST	P35222	CTNNB1	P53350	PLK1	S33	D32E	32	Missense	proximal	-1	no	11.011	10.214	EPSD	COSMIC	10.919	Loss
Other_PLK_PLK1_PLK1_ST	P35222	CTNNB1	P53350	PLK1	S33	H36R	36	Missense	distal	3	no	11.011	10.879	EPSD	COSMIC	10.919	Loss
Other_PLK_PLK1_PLK1_ST	P35222	CTNNB1	P53350	PLK1	S33	T40A	40	Missense	distal	7	no	11.011	11.051	EPSD	COSMIC	10.919	Up-regulation
Other_PLK_PLK1_PLK1_ST	P35222	CTNNB1	P53350	PLK1	S33	G34L	34	Missense	proximal	1	no	11.011	12.041	EPSD	COSMIC	10.919	Up-regulation
Other_PLK_PLK1_PLK1_ST	P35222	CTNNB1	P53350	PLK1	S33	S33L	33	Missense	central	0	yes	11.011	0.000	EPSD	COSMIC;CCLE	10.919	Loss
Other_PLK_PLK1_PLK1_ST	P35222	CTNNB1	P53350	PLK1	S33	S29P	29	Missense	distal	-4	no	11.011	10.889	EPSD	COSMIC	10.919	Loss
Other_PLK_PLK1_PLK1_ST	P35222	CTNNB1	P53350	PLK1	S33	L31P	31	Missense	proximal	-2	no	11.011	11.375	EPSD	COSMIC	10.919	Up-regulation
Other_PLK_PLK1_PLK1_ST	P35222	CTNNB1	P53350	PLK1	S33	S37L	37	Missense	distal	4	no	11.011	10.399	EPSD	COSMIC	10.919	Loss
Other_PLK_PLK1_PLK1_ST	P35222	CTNNB1	P53350	PLK1	S33	A39T	39	Missense	distal	6	no	11.011	11.004	EPSD	COSMIC	10.919	Down-regulation
Other_PLK_PLK1_PLK1_ST	P35222	CTNNB1	P53350	PLK1	S33	Q27H	27	Missense	distal	-6	no	11.011	11.022	EPSD	COSMIC	10.919	Up-regulation
Other_PLK_PLK1_PLK1_ST	P35222	CTNNB1	P53350	PLK1	S33	S33N	33	Missense	central	0	yes	11.011	0.000	EPSD	COSMIC	10.919	Loss
Other_PLK_PLK1_PLK1_ST	P35222	CTNNB1	P53350	PLK1	S33	H36Y	36	Missense	distal	3	no	11.011	10.823	EPSD	COSMIC	10.919	Loss
Other_PLK_PLK1_PLK1_ST	P35222	CTNNB1	P53350	PLK1	S33	S29F	29	Missense	distal	-4	no	11.011	10.693	EPSD	COSMIC	10.919	Loss
Other_PLK_PLK1_PLK1_ST	P35222	CTNNB1	P53350	PLK1	S33	Y30C	30	Missense	distal	-3	no	11.011	10.578	EPSD	COSMIC	10.919	Loss
Other_PLK_PLK1_PLK1_ST	P35222	CTNNB1	P53350	PLK1	S33	S29Y	29	Missense	distal	-4	no	11.011	10.324	EPSD	COSMIC	10.919	Loss
Other_PLK_PLK1_PLK1_ST	P35222	CTNNB1	P53350	PLK1	S33	G38P	38	Missense	distal	5	no	11.011	11.215	EPSD	COSMIC	10.919	Up-regulation
Other_PLK_PLK1_PLK1_ST	P35222	CTNNB1	P53350	PLK1	S33	G38D	38	Missense	distal	5	no	11.011	10.977	EPSD	COSMIC	10.919	Down-regulation
Other_PLK_PLK1_PLK1_ST	P35222	CTNNB1	P53350	PLK1	S33	I35M	35	Missense	proximal	2	no	11.011	10.587	EPSD	COSMIC	10.919	Loss
Other_PLK_PLK1_PLK1_ST	P35222	CTNNB1	P53350	PLK1	S33	T40S	40	Missense	distal	7	no	11.011	11.026	EPSD	COSMIC	10.919	Up-regulation
Other_PLK_PLK1_PLK1_ST	P35222	CTNNB1	P53350	PLK1	S33	S29A	29	Missense	distal	-4	no	11.011	11.050	EPSD	COSMIC	10.919	Up-regulation
Other_PLK_PLK1_PLK1_ST	P35222	CTNNB1	P53350	PLK1	S33	G34A	34	Missense	proximal	1	no	11.011	10.204	EPSD	COSMIC	10.919	Loss
Other_PLK_PLK1_PLK1_ST	P35222	CTNNB1	P53350	PLK1	S33	L31W	31	Missense	proximal	-2	no	11.011	5.074	EPSD	COSMIC	10.919	Loss
Other_PLK_PLK1_PLK1_ST	P35222	CTNNB1	P53350	PLK1	S33	G34I	34	Missense	proximal	1	no	11.011	11.833	EPSD	COSMIC	10.919	Up-regulation
Other_PLK_PLK1_PLK1_ST	P35222	CTNNB1	P53350	PLK1	S33	I35N	35	Missense	proximal	2	no	11.011	10.803	EPSD	COSMIC	10.919	Loss
Other_PLK_PLK1_PLK1_ST	P35222	CTNNB1	P53350	PLK1	S33	D32C	32	Missense	proximal	-1	no	11.011	8.358	EPSD	COSMIC	10.919	Loss
Other_PLK_PLK1_PLK1_ST	P35222	CTNNB1	P53350	PLK1	S33	Y30S	30	Missense	distal	-3	no	11.011	10.542	EPSD	COSMIC	10.919	Loss
Other_PLK_PLK1_PLK1_ST	P35222	CTNNB1	P53350	PLK1	S33	L31M	31	Missense	proximal	-2	no	11.011	11.503	EPSD	COSMIC	10.919	Up-regulation
Other_PLK_PLK1_PLK1_ST	P35222	CTNNB1	P53350	PLK1	S33	A39V	39	Missense	distal	6	no	11.011	10.836	EPSD	COSMIC	10.919	Loss
Other_PLK_PLK1_PLK1_ST	P35222	CTNNB1	P53350	PLK1	S33	L31Q	31	Missense	proximal	-2	no	11.011	11.558	EPSD	COSMIC	10.919	Up-regulation
Other_PLK_PLK1_PLK1_ST	P35222	CTNNB1	P53350	PLK1	S33	G34D	34	Missense	proximal	1	no	11.011	11.009	EPSD	COSMIC	10.919	Down-regulation
Other_PLK_PLK1_PLK1_ST	P35222	CTNNB1	P53350	PLK1	S33	Q26R	26	Missense	distal	-7	no	11.011	10.611	EPSD	COSMIC;GDSC;CCLE	10.919	Loss
Other_PLK_PLK1_PLK1_ST	P35222	CTNNB1	P53350	PLK1	S33	S37T	37	Missense	distal	4	no	11.011	10.819	EPSD	COSMIC	10.919	Loss
Other_PLK_PLK1_PLK1_ST	P35222	CTNNB1	P53350	PLK1	S33	I35K	35	Missense	proximal	2	no	11.011	9.829	EPSD	COSMIC	10.919	Loss
Other_PLK_PLK1_PLK1_ST	P35222	CTNNB1	P53350	PLK1	S33	Q28R	28	Missense	distal	-5	no	11.011	11.750	EPSD	COSMIC	10.919	Up-regulation
Other_PLK_PLK1_PLK1_ST	P35222	CTNNB1	P53350	PLK1	S33	D32F	32	Missense	proximal	-1	no	11.011	9.679	EPSD	COSMIC	10.919	Loss
Other_PLK_PLK1_PLK1_ST	P35222	CTNNB1	P53350	PLK1	S33	G38X	38	Missense	distal	5	no	11.011	11.123	EPSD	COSMIC	10.919	Up-regulation
Other_PLK_PLK1_PLK1_ST	P35222	CTNNB1	P53350	PLK1	S33	D32X	32	Missense	proximal	-1	no	11.011	8.980	EPSD	COSMIC	10.919	Loss
Other_PLK_PLK1_PLK1_ST	P35222	CTNNB1	P53350	PLK1	S33	S33K	33	Missense	central	0	yes	11.011	0.000	EPSD	COSMIC	10.919	Loss
Other_PLK_PLK1_PLK1_ST	P35222	CTNNB1	P53350	PLK1	S33	I35V	35	Missense	proximal	2	no	11.011	10.793	EPSD	COSMIC	10.919	Loss
Other_PLK_PLK1_PLK1_ST	P35222	CTNNB1	P53350	PLK1	S33	S29T	29	Missense	distal	-4	no	11.011	10.649	EPSD	COSMIC	10.919	Loss
Other_PLK_PLK1_PLK1_ST	P35222	CTNNB1	P53350	PLK1	S33	G34C	34	Missense	proximal	1	no	11.011	10.309	EPSD	COSMIC	10.919	Loss
Other_PLK_PLK1_PLK1_ST	P35222	CTNNB1	P53350	PLK1	S33	G38S	38	Missense	distal	5	no	11.011	10.828	EPSD	COSMIC	10.919	Loss
Other_PLK_PLK1_PLK1_ST	P35222	CTNNB1	P53350	PLK1	S33	S37V	37	Missense	distal	4	no	11.011	10.549	EPSD	COSMIC	10.919	Loss
Other_PLK_PLK1_PLK1_ST	P35222	CTNNB1	P53350	PLK1	S33	I35F	35	Missense	proximal	2	no	11.011	10.038	EPSD	COSMIC	10.919	Loss
Other_PLK_PLK1_PLK1_ST	P35222	CTNNB1	P53350	PLK1	S33	T40P	40	Missense	distal	7	no	11.011	11.053	EPSD	COSMIC	10.919	Up-regulation
Other_PLK_PLK1_PLK1_ST	P35222	CTNNB1	P53350	PLK1	S37	I35N	35	Missense	proximal	-2	no	9.087	11.061	EPSD	COSMIC	10.919	Gain
Other_PLK_PLK1_PLK1_ST	P35222	CTNNB1	P53350	PLK1	S47	P44L	44	Missense	distal	-3	no	9.731	10.923	EPSD	COSMIC	10.919	Gain
Other_PLK_PLK1_PLK1_ST	P35222	CTNNB1	P53350	PLK1	S47	S45E	45	Missense	proximal	-2	no	9.731	11.989	EPSD	COSMIC	10.919	Gain
Other_PLK_PLK1_PLK1_ST	P35222	CTNNB1	P53350	PLK1	S47	S45N	45	Missense	proximal	-2	no	9.731	11.141	EPSD	COSMIC	10.919	Gain
Other_PLK_PLK1_PLK1_ST	P35222	CTNNB1	P53350	PLK1	S60	E53K	53	Missense	distal	-7	no	11.105	10.801	EPSD	COSMIC	10.919	Loss
Other_PLK_PLK1_PLK1_ST	P35222	CTNNB1	P53350	PLK1	S60	E55G	55	Missense	distal	-5	no	11.105	11.601	EPSD	COSMIC	10.919	Up-regulation
Other_PLK_PLK1_PLK1_ST	P35222	CTNNB1	P53350	PLK1	S60	E54K	54	Missense	distal	-6	no	11.105	10.531	EPSD	COSMIC	10.919	Loss
Other_PLK_PLK1_PLK1_ST	P35222	CTNNB1	P53350	PLK1	S60	V62G	62	Missense	proximal	2	no	11.105	9.321	EPSD	COSMIC	10.919	Loss
Other_PLK_PLK1_PLK1_ST	P35222	CTNNB1	P53350	PLK1	S60	Q61R	61	Missense	proximal	1	no	11.105	9.126	EPSD	COSMIC	10.919	Loss
Other_PLK_PLK1_PLK1_ST	P35222	CTNNB1	P53350	PLK1	S60	D58N	58	Missense	proximal	-2	no	11.105	9.863	EPSD	COSMIC	10.919	Loss
Other_PLK_PLK1_PLK1_ST	P35222	CTNNB1	P53350	PLK1	S60	E54G	54	Missense	distal	-6	no	11.105	10.440	EPSD	COSMIC	10.919	Loss
Other_PLK_PLK1_PLK1_ST	P35222	CTNNB1	P53350	PLK1	S60	V57A	57	Missense	distal	-3	no	11.105	11.504	EPSD	COSMIC	10.919	Up-regulation
Other_PLK_PLK1_PLK1_ST	P35222	CTNNB1	P53350	PLK1	S60	S60C	60	Missense	central	0	yes	11.105	0.000	EPSD	COSMIC	10.919	Loss
Other_PLK_PLK1_PLK1_ST	P35222	CTNNB1	P53350	PLK1	S60	V57M	57	Missense	distal	-3	no	11.105	11.233	EPSD	COSMIC	10.919	Up-regulation
Other_PLK_PLK1_PLK1_ST	P35222	CTNNB1	P53350	PLK1	S60	Q61L	61	Missense	proximal	1	no	11.105	12.258	EPSD	COSMIC	10.919	Up-regulation
Other_PLK_PLK1_PLK1_ST	P35222	CTNNB1	P53350	PLK1	S60	E67K	67	Missense	distal	7	no	11.105	11.178	EPSD	COSMIC	10.919	Up-regulation
Other_PLK_PLK1_PLK1_ST	P35222	CTNNB1	P53350	PLK1	S60	E55L	55	Missense	distal	-5	no	11.105	11.867	EPSD	COSMIC	10.919	Up-regulation
Other_PLK_PLK1_PLK1_ST	P35222	CTNNB1	P53350	PLK1	S60	W66L	66	Missense	distal	6	no	11.105	11.431	EPSD	COSMIC	10.919	Up-regulation
Other_PLK_PLK1_PLK1_ST	P35222	CTNNB1	P53350	PLK1	S60	E65K	65	Missense	distal	5	no	11.105	11.116	EPSD	COSMIC	10.919	Up-regulation
Other_PLK_PLK1_PLK1_ST	P35222	CTNNB1	P53350	PLK1	S60	E67N	67	Missense	distal	7	no	11.105	11.183	EPSD	COSMIC	10.919	Up-regulation
Other_PLK_PLK1_PLK1_ST	P35222	CTNNB1	P53350	PLK1	S60	L63M	63	Missense	distal	3	no	11.105	10.962	EPSD	COSMIC	10.919	Down-regulation
Other_PLK_PLK1_PLK1_ST	P35222	CTNNB1	P53350	PLK1	S60	D56N	56	Missense	distal	-4	no	11.105	11.164	EPSD	COSMIC	10.919	Up-regulation
Other_PLK_PLK1_PLK1_ST	P35222	CTNNB1	P53350	PLK1	S60	E55D	55	Missense	distal	-5	no	11.105	11.447	EPSD	COSMIC	10.919	Up-regulation
Other_PLK_PLK1_PLK1_ST	P35222	CTNNB1	P53350	PLK1	S60	T59A	59	Missense	proximal	-1	no	11.105	11.385	EPSD	COSMIC	10.919	Up-regulation
Other_PLK_PLK1_PLK1_ST	P35222	CTNNB1	P53350	PLK1	S71	G69E	69	Missense	proximal	-2	no	9.317	12.245	EPSD	COSMIC	10.919	Gain
Other_PLK_PLK1_PLK1_ST	P35222	CTNNB1	P53350	PLK1	S73	E77K	77	Missense	distal	4	no	11.321	10.947	EPSD	COSMIC	10.919	Down-regulation
Other_PLK_PLK1_PLK1_ST	P35222	CTNNB1	P53350	PLK1	S73	Q76R	76	Missense	distal	3	no	11.321	11.125	EPSD	COSMIC	10.919	Down-regulation
Other_PLK_PLK1_PLK1_ST	P35222	CTNNB1	P53350	PLK1	S73	G69E	69	Missense	distal	-4	no	11.321	11.965	EPSD	COSMIC	10.919	Up-regulation
Other_PLK_PLK1_PLK1_ST	P35222	CTNNB1	P53350	PLK1	S73	V79I	79	Missense	distal	6	no	11.321	11.214	EPSD	COSMIC	10.919	Down-regulation
Other_PLK_PLK1_PLK1_ST	P35222	CTNNB1	P53350	PLK1	S73	E67K	67	Missense	distal	-6	no	11.321	10.747	EPSD	COSMIC	10.919	Loss
Other_PLK_PLK1_PLK1_ST	P35222	CTNNB1	P53350	PLK1	S73	W66L	66	Missense	distal	-7	no	11.321	10.927	EPSD	COSMIC	10.919	Down-regulation
Other_PLK_PLK1_PLK1_ST	P35222	CTNNB1	P53350	PLK1	S73	G69A	69	Missense	distal	-4	no	11.321	12.014	EPSD	COSMIC	10.919	Up-regulation
Other_PLK_PLK1_PLK1_ST	P35222	CTNNB1	P53350	PLK1	S73	E67N	67	Missense	distal	-6	no	11.321	11.005	EPSD	COSMIC	10.919	Down-regulation
Other_PLK_PLK1_PLK1_ST	P35222	CTNNB1	P53350	PLK1	S73	T75A	75	Missense	proximal	2	no	11.321	11.721	EPSD	COSMIC;GDSC;CCLE	10.919	Up-regulation
Other_PLK_PLK1_PLK1_ST	P35222	CTNNB1	P53350	PLK1	S73	Q76E	76	Missense	distal	3	no	11.321	11.429	EPSD	COSMIC	10.919	Up-regulation
Other_PLK_PLK1_PLK1_ST	P35222	CTNNB1	P53350	PLK1	S129	Q130H	130	Missense	proximal	1	no	12.097	11.515	EPSD	COSMIC	10.919	Down-regulation
Other_PLK_PLK1_PLK1_ST	P35222	CTNNB1	P53350	PLK1	S129	P128L	128	Missense	proximal	-1	no	12.097	12.811	EPSD	COSMIC	10.919	Up-regulation
Other_PLK_PLK1_PLK1_ST	P35222	CTNNB1	P53350	PLK1	S129	K133M	133	Missense	distal	4	no	12.097	11.533	EPSD	COSMIC	10.919	Down-regulation
Other_PLK_PLK1_PLK1_ST	P35222	CTNNB1	P53350	PLK1	S129	V122G	122	Missense	distal	-7	no	12.097	11.698	EPSD	COSMIC	10.919	Down-regulation
Other_PLK_PLK1_PLK1_ST	P35222	CTNNB1	P53350	PLK1	S246	G245D	245	Missense	proximal	-1	no	9.167	11.756	EPSD	COSMIC	10.919	Gain
Other_PLK_PLK1_PLK1_ST	P35222	CTNNB1	P53350	PLK1	S250	M243T	243	Missense	distal	-7	no	11.759	12.181	EPSD	COSMIC	10.919	Up-regulation
Other_PLK_PLK1_PLK1_ST	P35222	CTNNB1	P53350	PLK1	S250	T257I	257	Missense	distal	7	no	11.759	11.806	EPSD	COSMIC	10.919	Up-regulation
Other_PLK_PLK1_PLK1_ST	P35222	CTNNB1	P53350	PLK1	S250	A255T	255	Missense	distal	5	no	11.759	10.588	EPSD	COSMIC	10.919	Loss
Other_PLK_PLK1_PLK1_ST	P35222	CTNNB1	P53350	PLK1	S250	S246L	246	Missense	distal	-4	no	11.759	11.566	EPSD	COSMIC	10.919	Down-regulation
Other_PLK_PLK1_PLK1_ST	P35222	CTNNB1	P53350	PLK1	S250	G245A	245	Missense	distal	-5	no	11.759	11.644	EPSD	COSMIC;GDSC	10.919	Down-regulation
Other_PLK_PLK1_PLK1_ST	P35222	CTNNB1	P53350	PLK1	S250	G245D	245	Missense	distal	-5	no	11.759	11.605	EPSD	COSMIC	10.919	Down-regulation
Other_PLK_PLK1_PLK1_ST	P35222	CTNNB1	P53350	PLK1	S552	G554D	554	Missense	proximal	2	no	9.522	11.101	EPSD	COSMIC	10.919	Gain
Other_PLK_PLK1_PLK1_ST	P35222	CTNNB1	P53350	PLK1	T679	R673W	673	Missense	distal	-6	no	11.192	10.735	EPSD	COSMIC	10.919	Loss
Other_PLK_PLK1_PLK1_ST	P35222	CTNNB1	P53350	PLK1	T679	S680I	680	Missense	proximal	1	no	11.192	12.951	EPSD	COSMIC	10.919	Up-regulation
Other_PLK_PLK1_PLK1_ST	P35222	CTNNB1	P53350	PLK1	T679	E677D	677	Missense	proximal	-2	no	11.192	11.586	EPSD	COSMIC	10.919	Up-regulation
Other_PLK_PLK1_PLK1_ST	P35222	CTNNB1	P53350	PLK1	T679	R673H	673	Missense	distal	-6	no	11.192	11.651	EPSD	COSMIC	10.919	Up-regulation
Other_PLK_PLK1_PLK1_ST	P35222	CTNNB1	P53350	PLK1	T679	L678F	678	Missense	proximal	-1	no	11.192	11.113	EPSD	COSMIC	10.919	Down-regulation
Other_PLK_PLK1_PLK1_ST	P35222	CTNNB1	P53350	PLK1	T679	R673C	673	Missense	distal	-6	no	11.192	10.436	EPSD	COSMIC	10.919	Loss
Other_PLK_PLK1_PLK1_ST	P35222	CTNNB1	P53350	PLK1	T679	E686G	686	Missense	distal	7	no	11.192	11.213	EPSD	COSMIC	10.919	Up-regulation
Other_PLK_PLK1_PLK1_ST	P35222	CTNNB1	P53350	PLK1	S715	H720P	720	Missense	distal	5	no	10.651	11.344	EPSD	COSMIC	10.919	Gain
Other_PLK_PLK1_PLK1_ST	P35222	CTNNB1	P53350	PLK1	S715	P714S	714	Missense	proximal	-1	no	10.651	11.825	EPSD	COSMIC	10.919	Gain
Other_PLK_PLK1_PLK1_ST	P35222	CTNNB1	P53350	PLK1	S718	Y716C	716	Missense	proximal	-2	no	14.009	10.499	PhosphoSitePlus	COSMIC	10.919	Loss
Other_PLK_PLK1_PLK1_ST	P35222	CTNNB1	P53350	PLK1	S718	H720P	720	Missense	proximal	2	no	14.009	12.558	PhosphoSitePlus	COSMIC	10.919	Down-regulation
Other_PLK_PLK1_PLK1_ST	P35222	CTNNB1	P53350	PLK1	S718	R717C	717	Missense	proximal	-1	no	14.009	13.085	PhosphoSitePlus	COSMIC	10.919	Down-regulation
Other_PLK_PLK1_PLK1_ST	P35222	CTNNB1	P53350	PLK1	S718	S715R	715	Missense	distal	-3	no	14.009	14.841	PhosphoSitePlus	COSMIC	10.919	Up-regulation
Other_PLK_PLK1_PLK1_ST	P35222	CTNNB1	P53350	PLK1	S718	D712N	712	Missense	distal	-6	no	14.009	13.896	PhosphoSitePlus	COSMIC	10.919	Down-regulation
Other_PLK_PLK1_PLK1_ST	P35222	CTNNB1	P53350	PLK1	S718	P714S	714	Missense	distal	-4	no	14.009	14.131	PhosphoSitePlus	COSMIC	10.919	Up-regulation
Other_PLK_PLK1_PLK1_ST	P35222	CTNNB1	P53350	PLK1	S718	Y724S	724	Missense	distal	6	no	14.009	14.537	PhosphoSitePlus	COSMIC	10.919	Up-regulation
Other_PLK_PLK1_PLK1_ST	P35222	CTNNB1	P53350	PLK1	S718	G723S	723	Missense	distal	5	no	14.009	13.826	PhosphoSitePlus	COSMIC	10.919	Down-regulation
Other_PLK_PLK1_PLK1_ST	P35222	CTNNB1	P53350	PLK1	S718	Y724C	724	Missense	distal	6	no	14.009	13.604	PhosphoSitePlus	COSMIC	10.919	Down-regulation
Other_PLK_PLK1_PLK1_ST	P35222	CTNNB1	P53350	PLK1	S718	G725D	725	Missense	distal	7	no	14.009	13.984	PhosphoSitePlus	COSMIC	10.919	Down-regulation
Other_PLK_PLK1_PLK1_ST	O94901	SUN1	P53350	PLK1	S75	A80T	80	Missense	distal	5	no	12.337	11.166	EPSD	COSMIC	10.919	Down-regulation
Other_PLK_PLK1_PLK1_ST	O94901	SUN1	P53350	PLK1	S75	S82F	82	Missense	distal	7	no	12.337	12.407	EPSD	COSMIC	10.919	Up-regulation
Other_PLK_PLK1_PLK1_ST	O94901	SUN1	P53350	PLK1	S75	A80S	80	Missense	distal	5	no	12.337	11.771	EPSD	COSMIC	10.919	Down-regulation
Other_PLK_PLK1_PLK1_ST	O94901	SUN1	P53350	PLK1	S123	A127T	127	Missense	distal	4	no	10.959	10.965	EPSD	COSMIC	10.919	Up-regulation
Other_PLK_PLK1_PLK1_ST	O94901	SUN1	P53350	PLK1	S123	G120W	120	Missense	distal	-3	no	10.959	10.237	EPSD	COSMIC	10.919	Loss
Other_PLK_PLK1_PLK1_ST	O94901	SUN1	P53350	PLK1	T199	A204T	204	Missense	distal	5	no	11.150	9.978	EPSD	COSMIC;GDSC;CCLE	10.919	Loss
Other_PLK_PLK1_PLK1_ST	O94901	SUN1	P53350	PLK1	T199	A204V	204	Missense	distal	5	no	11.150	10.411	EPSD	COSMIC	10.919	Loss
Other_PLK_PLK1_PLK1_ST	O94901	SUN1	P53350	PLK1	T199	R194L	194	Missense	distal	-5	no	11.150	11.130	EPSD	COSMIC	10.919	Down-regulation
Other_PLK_PLK1_PLK1_ST	O94901	SUN1	P53350	PLK1	T199	E193K	193	Missense	distal	-6	no	11.150	10.576	EPSD	COSMIC	10.919	Loss
Other_PLK_PLK1_PLK1_ST	O94901	SUN1	P53350	PLK1	T199	A203V	203	Missense	distal	4	no	11.150	10.886	EPSD	COSMIC	10.919	Loss
Other_PLK_PLK1_PLK1_ST	O94901	SUN1	P53350	PLK1	T199	T199A	199	Missense	central	0	yes	11.150	0.000	EPSD	COSMIC	10.919	Loss
Other_PLK_PLK1_PLK1_ST	O94901	SUN1	P53350	PLK1	T199	A200T	200	Missense	proximal	1	no	11.150	11.612	EPSD	COSMIC	10.919	Up-regulation
Other_PLK_PLK1_PLK1_ST	O94901	SUN1	P53350	PLK1	T199	S192Y	192	Missense	distal	-7	no	11.150	10.538	EPSD	COSMIC	10.919	Loss
Other_PLK_PLK1_PLK1_ST	O94901	SUN1	P53350	PLK1	T199	S192C	192	Missense	distal	-7	no	11.150	10.532	EPSD	COSMIC	10.919	Loss
Other_PLK_PLK1_PLK1_ST	P06748	NPM1	P53350	PLK1	S10	R13S	13	Missense	distal	3	no	11.004	11.128	EPSD	COSMIC	10.919	Up-regulation
Other_PLK_PLK1_PLK1_ST	P06748	NPM1	P53350	PLK1	S10	P14L	14	Missense	distal	4	no	11.004	10.714	EPSD	COSMIC	10.919	Loss
Other_PLK_PLK1_PLK1_ST	P06748	NPM1	P53350	PLK1	S70	G69D	69	Missense	proximal	-1	no	11.260	13.850	EPSD	COSMIC;GDSC;CCLE	10.919	Up-regulation
Other_PLK_PLK1_PLK1_ST	Q13158	FADD	P53350	PLK1	S69	R71W	71	Missense	proximal	2	no	11.094	11.841	EPSD	COSMIC	10.919	Up-regulation
Other_PLK_PLK1_PLK1_ST	Q13158	FADD	P53350	PLK1	S128	I126N	126	Missense	proximal	-2	no	9.849	11.823	EPSD	COSMIC	10.919	Gain
Other_PLK_PLK1_PLK1_ST	Q13158	FADD	P53350	PLK1	S190	S194F	194	Missense	distal	4	no	11.755	10.941	EPSD	COSMIC	10.919	Down-regulation
Other_PLK_PLK1_PLK1_ST	Q13158	FADD	P53350	PLK1	S194	S194F	194	Missense	central	0	yes	13.059	0.000	PhosphoSitePlus	COSMIC	10.919	Loss
Other_PLK_PLK1_PLK1_ST	Q13158	FADD	P53350	PLK1	S197	S194F	194	Missense	distal	-3	no	11.761	11.131	EPSD	COSMIC	10.919	Down-regulation
Other_PLK_PLK1_PLK1_ST	P38398	BRCA1	P53350	PLK1	S76	Q81E	81	Missense	distal	5	no	10.785	10.945	EPSD	COSMIC	10.919	Gain
Other_PLK_PLK1_PLK1_ST	P38398	BRCA1	P53350	PLK1	S76	T77M	77	Missense	proximal	1	no	10.785	12.917	EPSD	COSMIC	10.919	Gain
Other_PLK_PLK1_PLK1_ST	P38398	BRCA1	P53350	PLK1	S76	Q81R	81	Missense	distal	5	no	10.785	11.581	EPSD	COSMIC	10.919	Gain
Other_PLK_PLK1_PLK1_ST	P38398	BRCA1	P53350	PLK1	S114	D120A	120	Missense	distal	6	no	12.949	12.961	EPSD	COSMIC	10.919	Up-regulation
Other_PLK_PLK1_PLK1_ST	P38398	BRCA1	P53350	PLK1	S114	P115L	115	Missense	proximal	1	no	12.949	13.795	EPSD	COSMIC	10.919	Up-regulation
Other_PLK_PLK1_PLK1_ST	P38398	BRCA1	P53350	PLK1	S114	F107Y	107	Missense	distal	-7	no	12.949	12.795	EPSD	COSMIC	10.919	Down-regulation
Other_PLK_PLK1_PLK1_ST	P38398	BRCA1	P53350	PLK1	S114	N113S	113	Missense	proximal	-1	no	12.949	13.090	EPSD	COSMIC	10.919	Up-regulation
Other_PLK_PLK1_PLK1_ST	P38398	BRCA1	P53350	PLK1	S114	E111K	111	Missense	distal	-3	no	12.949	13.490	EPSD	COSMIC	10.919	Up-regulation
Other_PLK_PLK1_PLK1_ST	P38398	BRCA1	P53350	PLK1	S114	A108V	108	Missense	distal	-6	no	12.949	12.710	EPSD	COSMIC	10.919	Down-regulation
Other_PLK_PLK1_PLK1_ST	P38398	BRCA1	P53350	PLK1	S114	E116K	116	Missense	proximal	2	no	12.949	12.780	EPSD	COSMIC	10.919	Down-regulation
Other_PLK_PLK1_PLK1_ST	P38398	BRCA1	P53350	PLK1	S114	P115R	115	Missense	proximal	1	no	12.949	10.664	EPSD	COSMIC	10.919	Loss
Other_PLK_PLK1_PLK1_ST	P38398	BRCA1	P53350	PLK1	S123	D120A	120	Missense	distal	-3	no	14.179	14.412	EPSD	COSMIC	10.919	Up-regulation
Other_PLK_PLK1_PLK1_ST	P38398	BRCA1	P53350	PLK1	S123	S127N	127	Missense	distal	4	no	14.179	13.943	EPSD	COSMIC	10.919	Down-regulation
Other_PLK_PLK1_PLK1_ST	P38398	BRCA1	P53350	PLK1	S123	E116K	116	Missense	distal	-7	no	14.179	13.875	EPSD	COSMIC	10.919	Down-regulation
Other_PLK_PLK1_PLK1_ST	P38398	BRCA1	P53350	PLK1	S123	I124T	124	Missense	proximal	1	no	14.179	13.013	EPSD	COSMIC	10.919	Down-regulation
Other_PLK_PLK1_PLK1_ST	P38398	BRCA1	P53350	PLK1	S187	G183A	183	Missense	distal	-4	no	11.737	12.431	EPSD	COSMIC	10.919	Up-regulation
Other_PLK_PLK1_PLK1_ST	P38398	BRCA1	P53350	PLK1	S187	L182S	182	Missense	distal	-5	no	11.737	11.073	EPSD	COSMIC	10.919	Down-regulation
Other_PLK_PLK1_PLK1_ST	P38398	BRCA1	P53350	PLK1	S187	N192Y	192	Missense	distal	5	no	11.737	12.184	EPSD	COSMIC	10.919	Up-regulation
Other_PLK_PLK1_PLK1_ST	P38398	BRCA1	P53350	PLK1	S187	N192S	192	Missense	distal	5	no	11.737	12.341	EPSD	COSMIC	10.919	Up-regulation
Other_PLK_PLK1_PLK1_ST	P38398	BRCA1	P53350	PLK1	T190	G183A	183	Missense	distal	-7	no	11.651	11.993	EPSD	COSMIC	10.919	Up-regulation
Other_PLK_PLK1_PLK1_ST	P38398	BRCA1	P53350	PLK1	T190	C197F	197	Missense	distal	7	no	11.651	11.652	EPSD	COSMIC	10.919	Up-regulation
Other_PLK_PLK1_PLK1_ST	P38398	BRCA1	P53350	PLK1	T190	N192Y	192	Missense	proximal	2	no	11.651	11.070	EPSD	COSMIC	10.919	Down-regulation
Other_PLK_PLK1_PLK1_ST	P38398	BRCA1	P53350	PLK1	T190	N192S	192	Missense	proximal	2	no	11.651	11.437	EPSD	COSMIC	10.919	Down-regulation
Other_PLK_PLK1_PLK1_ST	P38398	BRCA1	P53350	PLK1	T208	L204F	204	Missense	distal	-4	no	11.967	11.842	EPSD	COSMIC	10.919	Down-regulation
Other_PLK_PLK1_PLK1_ST	P38398	BRCA1	P53350	PLK1	T208	E215K	215	Missense	distal	7	no	11.967	12.040	EPSD	COSMIC	10.919	Up-regulation
Other_PLK_PLK1_PLK1_ST	P38398	BRCA1	P53350	PLK1	T208	Q202R	202	Missense	distal	-6	no	11.967	11.519	EPSD	COSMIC	10.919	Down-regulation
Other_PLK_PLK1_PLK1_ST	P38398	BRCA1	P53350	PLK1	T208	Q210E	210	Missense	proximal	2	no	11.967	11.778	EPSD	COSMIC	10.919	Down-regulation
Other_PLK_PLK1_PLK1_ST	P38398	BRCA1	P53350	PLK1	T208	E203K	203	Missense	distal	-5	no	11.967	12.210	EPSD	COSMIC	10.919	Up-regulation
Other_PLK_PLK1_PLK1_ST	P38398	BRCA1	P53350	PLK1	S229	T231N	231	Missense	proximal	2	no	10.138	10.992	EPSD	COSMIC	10.919	Gain
Other_PLK_PLK1_PLK1_ST	P38398	BRCA1	P53350	PLK1	S398	G401E	401	Missense	distal	3	no	13.579	13.755	EPSD	COSMIC;GDSC;CCLE	10.919	Up-regulation
Other_PLK_PLK1_PLK1_ST	P38398	BRCA1	P53350	PLK1	S398	H399R	399	Missense	proximal	1	no	13.579	12.182	EPSD	COSMIC	10.919	Down-regulation
Other_PLK_PLK1_PLK1_ST	P38398	BRCA1	P53350	PLK1	S398	S395F	395	Missense	distal	-3	no	13.579	12.949	EPSD	COSMIC	10.919	Down-regulation
Other_PLK_PLK1_PLK1_ST	P38398	BRCA1	P53350	PLK1	S398	G401V	401	Missense	distal	3	no	13.579	13.727	EPSD	COSMIC	10.919	Up-regulation
Other_PLK_PLK1_PLK1_ST	P38398	BRCA1	P53350	PLK1	S405	G401E	401	Missense	distal	-4	no	10.794	11.438	EPSD	COSMIC;GDSC;CCLE	10.919	Gain
Other_PLK_PLK1_PLK1_ST	P38398	BRCA1	P53350	PLK1	S405	K408E	408	Missense	distal	3	no	10.794	11.000	EPSD	COSMIC	10.919	Gain
Other_PLK_PLK1_PLK1_ST	P38398	BRCA1	P53350	PLK1	S405	G401V	401	Missense	distal	-4	no	10.794	11.347	EPSD	COSMIC	10.919	Gain
Other_PLK_PLK1_PLK1_ST	P38398	BRCA1	P53350	PLK1	S425	S426L	426	Missense	proximal	1	no	10.138	12.105	EPSD	COSMIC	10.919	Gain
Other_PLK_PLK1_PLK1_ST	P38398	BRCA1	P53350	PLK1	S449	H448R	448	Missense	proximal	-1	no	11.067	10.070	EPSD	COSMIC	10.919	Loss
Other_PLK_PLK1_PLK1_ST	P38398	BRCA1	P53350	PLK1	S449	K443E	443	Missense	distal	-6	no	11.067	11.641	EPSD	COSMIC	10.919	Up-regulation
Other_PLK_PLK1_PLK1_ST	P38398	BRCA1	P53350	PLK1	S449	N455T	455	Missense	distal	6	no	11.067	11.292	EPSD	COSMIC	10.919	Up-regulation
Other_PLK_PLK1_PLK1_ST	P38398	BRCA1	P53350	PLK1	S449	I456T	456	Missense	distal	7	no	11.067	11.020	EPSD	COSMIC;GDSC;CCLE	10.919	Down-regulation
Other_PLK_PLK1_PLK1_ST	P38398	BRCA1	P53350	PLK1	S603	K608N	608	Missense	distal	5	no	12.032	11.709	EPSD	COSMIC	10.919	Down-regulation
Other_PLK_PLK1_PLK1_ST	P38398	BRCA1	P53350	PLK1	S603	R610S	610	Missense	distal	7	no	12.032	12.016	EPSD	COSMIC	10.919	Down-regulation
Other_PLK_PLK1_PLK1_ST	P38398	BRCA1	P53350	PLK1	S603	K604E	604	Missense	proximal	1	no	12.032	12.482	EPSD	COSMIC;GDSC;CCLE	10.919	Up-regulation
Other_PLK_PLK1_PLK1_ST	P38398	BRCA1	P53350	PLK1	S603	K607R	607	Missense	distal	4	no	12.032	11.472	EPSD	COSMIC	10.919	Down-regulation
Other_PLK_PLK1_PLK1_ST	P38398	BRCA1	P53350	PLK1	S632	P634S	634	Missense	proximal	2	no	10.718	12.194	EPSD	COSMIC	10.919	Gain
Other_PLK_PLK1_PLK1_ST	P38398	BRCA1	P53350	PLK1	S632	P634R	634	Missense	proximal	2	no	10.718	11.466	EPSD	COSMIC	10.919	Gain
Other_PLK_PLK1_PLK1_ST	P38398	BRCA1	P53350	PLK1	T696	S694N	694	Missense	proximal	-2	no	10.350	11.759	EPSD	COSMIC	10.919	Gain
Other_PLK_PLK1_PLK1_ST	P38398	BRCA1	P53350	PLK1	T696	S694Y	694	Missense	proximal	-2	no	10.350	11.460	EPSD	COSMIC	10.919	Gain
Other_PLK_PLK1_PLK1_ST	P38398	BRCA1	P53350	PLK1	S763	S770L	770	Missense	distal	7	no	12.964	12.962	EPSD	COSMIC	10.919	Down-regulation
Other_PLK_PLK1_PLK1_ST	P38398	BRCA1	P53350	PLK1	S763	S763F	763	Missense	central	0	yes	12.964	0.000	EPSD	COSMIC;GDSC;CCLE	10.919	Loss
Other_PLK_PLK1_PLK1_ST	P38398	BRCA1	P53350	PLK1	S763	E765K	765	Missense	proximal	2	no	12.964	12.794	EPSD	COSMIC	10.919	Down-regulation
Other_PLK_PLK1_PLK1_ST	P38398	BRCA1	P53350	PLK1	S763	V757A	757	Missense	distal	-6	no	12.964	13.203	EPSD	COSMIC	10.919	Up-regulation
Other_PLK_PLK1_PLK1_ST	P38398	BRCA1	P53350	PLK1	S763	L758F	758	Missense	distal	-5	no	12.964	12.039	EPSD	COSMIC	10.919	Down-regulation
Other_PLK_PLK1_PLK1_ST	P38398	BRCA1	P53350	PLK1	S767	S770L	770	Missense	distal	3	no	12.355	12.208	EPSD	COSMIC	10.919	Down-regulation
Other_PLK_PLK1_PLK1_ST	P38398	BRCA1	P53350	PLK1	S767	S763F	763	Missense	distal	-4	no	12.355	12.036	EPSD	COSMIC;GDSC;CCLE	10.919	Down-regulation
Other_PLK_PLK1_PLK1_ST	P38398	BRCA1	P53350	PLK1	S767	P773S	773	Missense	distal	6	no	12.355	12.211	EPSD	COSMIC	10.919	Down-regulation
Other_PLK_PLK1_PLK1_ST	P38398	BRCA1	P53350	PLK1	S767	E765K	765	Missense	proximal	-2	no	12.355	9.477	EPSD	COSMIC	10.919	Loss
Other_PLK_PLK1_PLK1_ST	P38398	BRCA1	P53350	PLK1	S767	V772A	772	Missense	distal	5	no	12.355	13.093	EPSD	COSMIC;GDSC	10.919	Up-regulation
Other_PLK_PLK1_PLK1_ST	P38398	BRCA1	P53350	PLK1	S840	R841W	841	Missense	proximal	1	no	8.255	10.959	EPSD	COSMIC	10.919	Gain
Other_PLK_PLK1_PLK1_ST	P38398	BRCA1	P53350	PLK1	S844	E842K	842	Missense	proximal	-2	no	11.509	8.631	EPSD	COSMIC	10.919	Loss
Other_PLK_PLK1_PLK1_ST	P38398	BRCA1	P53350	PLK1	S844	R841W	841	Missense	distal	-3	no	11.509	10.727	EPSD	COSMIC	10.919	Loss
Other_PLK_PLK1_PLK1_ST	P38398	BRCA1	P53350	PLK1	S844	E849G	849	Missense	distal	5	no	11.509	11.983	EPSD	COSMIC	10.919	Up-regulation
Other_PLK_PLK1_PLK1_ST	P38398	BRCA1	P53350	PLK1	S844	T843A	843	Missense	proximal	-1	no	11.509	11.789	EPSD	COSMIC;GDSC;CCLE	10.919	Up-regulation
Other_PLK_PLK1_PLK1_ST	P38398	BRCA1	P53350	PLK1	S868	P871L	871	Missense	distal	3	no	12.088	11.920	EPSD	COSMIC	10.919	Down-regulation
Other_PLK_PLK1_PLK1_ST	P38398	BRCA1	P53350	PLK1	S868	S868L	868	Missense	central	0	yes	12.088	0.000	EPSD	COSMIC	10.919	Loss
Other_PLK_PLK1_PLK1_ST	P38398	BRCA1	P53350	PLK1	S868	S864L	864	Missense	distal	-4	no	12.088	11.895	EPSD	COSMIC	10.919	Down-regulation
Other_PLK_PLK1_PLK1_ST	P38398	BRCA1	P53350	PLK1	S868	K865N	865	Missense	distal	-3	no	12.088	11.906	EPSD	COSMIC	10.919	Down-regulation
Other_PLK_PLK1_PLK1_ST	P38398	BRCA1	P53350	PLK1	T963	E962K	962	Missense	proximal	-1	no	12.354	11.782	EPSD	COSMIC;GDSC;CCLE	10.919	Down-regulation
Other_PLK_PLK1_PLK1_ST	P38398	BRCA1	P53350	PLK1	T963	T967I	967	Missense	distal	4	no	12.354	11.355	EPSD	COSMIC	10.919	Down-regulation
Other_PLK_PLK1_PLK1_ST	P38398	BRCA1	P53350	PLK1	T963	N969I	969	Missense	distal	6	no	12.354	12.304	EPSD	COSMIC	10.919	Down-regulation
Other_PLK_PLK1_PLK1_ST	P38398	BRCA1	P53350	PLK1	S988	I986M	986	Missense	proximal	-2	no	11.154	11.262	EPSD	COSMIC	10.919	Up-regulation
Other_PLK_PLK1_PLK1_ST	P38398	BRCA1	P53350	PLK1	S1007	E1011K	1011	Missense	distal	4	no	13.576	13.203	EPSD	COSMIC	10.919	Down-regulation
Other_PLK_PLK1_PLK1_ST	P38398	BRCA1	P53350	PLK1	S1007	M1008I	1008	Missense	proximal	1	no	13.576	12.611	EPSD	COSMIC;GDSC	10.919	Down-regulation
Other_PLK_PLK1_PLK1_ST	P38398	BRCA1	P53350	PLK1	S1007	M1014I	1014	Missense	distal	7	no	13.576	13.540	EPSD	COSMIC;GDSC;CCLE	10.919	Down-regulation
Other_PLK_PLK1_PLK1_ST	P38398	BRCA1	P53350	PLK1	S1007	M1014K	1014	Missense	distal	7	no	13.576	13.559	EPSD	COSMIC	10.919	Down-regulation
Other_PLK_PLK1_PLK1_ST	P38398	BRCA1	P53350	PLK1	S1007	S1009F	1009	Missense	proximal	2	no	13.576	13.025	EPSD	COSMIC	10.919	Down-regulation
Other_PLK_PLK1_PLK1_ST	P38398	BRCA1	P53350	PLK1	S1007	E1013D	1013	Missense	distal	6	no	13.576	13.726	EPSD	COSMIC	10.919	Up-regulation
Other_PLK_PLK1_PLK1_ST	P38398	BRCA1	P53350	PLK1	S1164	T1163A	1163	Missense	proximal	-1	no	13.392	13.672	PhosphoSitePlus	COSMIC	10.919	Up-regulation
Other_PLK_PLK1_PLK1_ST	P38398	BRCA1	P53350	PLK1	S1164	E1167K	1167	Missense	distal	3	no	13.392	13.186	PhosphoSitePlus	COSMIC	10.919	Down-regulation
Other_PLK_PLK1_PLK1_ST	P38398	BRCA1	P53350	PLK1	S1174	S1180I	1180	Missense	distal	6	no	13.313	13.314	EPSD	COSMIC	10.919	Up-regulation
Other_PLK_PLK1_PLK1_ST	P38398	BRCA1	P53350	PLK1	S1174	E1167K	1167	Missense	distal	-7	no	13.313	13.009	EPSD	COSMIC	10.919	Down-regulation
Other_PLK_PLK1_PLK1_ST	P38398	BRCA1	P53350	PLK1	S1266	L1260V	1260	Missense	distal	-6	no	12.154	12.213	EPSD	COSMIC	10.919	Up-regulation
Other_PLK_PLK1_PLK1_ST	P38398	BRCA1	P53350	PLK1	S1266	L1263F	1263	Missense	distal	-3	no	12.154	10.750	EPSD	COSMIC	10.919	Loss
Other_PLK_PLK1_PLK1_ST	P38398	BRCA1	P53350	PLK1	S1266	K1264N	1264	Missense	proximal	-2	no	12.154	14.182	EPSD	COSMIC	10.919	Up-regulation
Other_PLK_PLK1_PLK1_ST	P38398	BRCA1	P53350	PLK1	S1484	P1491L	1491	Missense	distal	7	no	13.037	13.008	EPSD	COSMIC	10.919	Down-regulation
Other_PLK_PLK1_PLK1_ST	P38398	BRCA1	P53350	PLK1	S1484	S1483C	1483	Missense	proximal	-1	no	13.037	11.176	EPSD	COSMIC	10.919	Down-regulation
Other_PLK_PLK1_PLK1_ST	P38398	BRCA1	P53350	PLK1	S1484	E1490Q	1490	Missense	distal	6	no	13.037	12.896	EPSD	COSMIC	10.919	Down-regulation
Other_PLK_PLK1_PLK1_ST	P38398	BRCA1	P53350	PLK1	S1484	E1478Q	1478	Missense	distal	-6	no	13.037	12.918	EPSD	COSMIC	10.919	Down-regulation
Other_PLK_PLK1_PLK1_ST	P38398	BRCA1	P53350	PLK1	S1484	T1485S	1485	Missense	proximal	1	no	13.037	12.445	EPSD	COSMIC	10.919	Down-regulation
Other_PLK_PLK1_PLK1_ST	P38398	BRCA1	P53350	PLK1	S1484	N1488S	1488	Missense	distal	4	no	13.037	13.273	EPSD	COSMIC	10.919	Up-regulation
Other_PLK_PLK1_PLK1_ST	P38398	BRCA1	P53350	PLK1	S1542	D1546Y	1546	Missense	distal	4	no	12.204	11.958	EPSD	COSMIC	10.919	Down-regulation
Other_PLK_PLK1_PLK1_ST	P38398	BRCA1	P53350	PLK1	S1542	E1540K	1540	Missense	proximal	-2	no	12.204	9.327	EPSD	COSMIC	10.919	Loss
Other_PLK_PLK1_PLK1_ST	P38398	BRCA1	P53350	PLK1	S1542	D1546N	1546	Missense	distal	4	no	12.204	11.965	EPSD	COSMIC;GDSC	10.919	Down-regulation
Other_PLK_PLK1_PLK1_ST	P38398	BRCA1	P53350	PLK1	S1542	T1548M	1548	Missense	distal	6	no	12.204	11.674	EPSD	COSMIC;GDSC;CCLE	10.919	Down-regulation
Other_PLK_PLK1_PLK1_ST	P38398	BRCA1	P53350	PLK1	S1542	E1536K	1536	Missense	distal	-6	no	12.204	11.630	EPSD	COSMIC	10.919	Down-regulation
Other_PLK_PLK1_PLK1_ST	P38398	BRCA1	P53350	PLK1	S1542	L1547F	1547	Missense	distal	5	no	12.204	12.645	EPSD	COSMIC	10.919	Up-regulation
Other_PLK_PLK1_PLK1_ST	P38398	BRCA1	P53350	PLK1	S1542	G1543V	1543	Missense	proximal	1	no	12.204	12.835	EPSD	COSMIC	10.919	Up-regulation
Other_PLK_PLK1_PLK1_ST	P38398	BRCA1	P53350	PLK1	T1548	D1546Y	1546	Missense	proximal	-2	no	11.427	9.885	EPSD	COSMIC	10.919	Loss
Other_PLK_PLK1_PLK1_ST	P38398	BRCA1	P53350	PLK1	T1548	D1546N	1546	Missense	proximal	-2	no	11.427	10.184	EPSD	COSMIC;GDSC	10.919	Loss
Other_PLK_PLK1_PLK1_ST	P38398	BRCA1	P53350	PLK1	T1548	S1551C	1551	Missense	distal	3	no	11.427	11.362	EPSD	COSMIC	10.919	Down-regulation
Other_PLK_PLK1_PLK1_ST	P38398	BRCA1	P53350	PLK1	T1548	T1548M	1548	Missense	central	0	yes	11.427	0.000	EPSD	COSMIC;GDSC;CCLE	10.919	Loss
Other_PLK_PLK1_PLK1_ST	P38398	BRCA1	P53350	PLK1	T1548	L1547F	1547	Missense	proximal	-1	no	11.427	11.348	EPSD	COSMIC	10.919	Down-regulation
Other_PLK_PLK1_PLK1_ST	P38398	BRCA1	P53350	PLK1	T1548	G1543V	1543	Missense	distal	-5	no	11.427	11.239	EPSD	COSMIC	10.919	Down-regulation
Other_PLK_PLK1_PLK1_ST	P38398	BRCA1	P53350	PLK1	T1548	S1551T	1551	Missense	distal	3	no	11.427	11.290	EPSD	COSMIC	10.919	Down-regulation
Other_PLK_PLK1_PLK1_ST	P38398	BRCA1	P53350	PLK1	S1551	D1546Y	1546	Missense	distal	-5	no	12.480	12.334	EPSD	COSMIC	10.919	Down-regulation
Other_PLK_PLK1_PLK1_ST	P38398	BRCA1	P53350	PLK1	S1551	D1546N	1546	Missense	distal	-5	no	12.480	12.183	EPSD	COSMIC;GDSC	10.919	Down-regulation
Other_PLK_PLK1_PLK1_ST	P38398	BRCA1	P53350	PLK1	S1551	S1551C	1551	Missense	central	0	yes	12.480	0.000	EPSD	COSMIC	10.919	Loss
Other_PLK_PLK1_PLK1_ST	P38398	BRCA1	P53350	PLK1	S1551	T1548M	1548	Missense	distal	-3	no	12.480	12.355	EPSD	COSMIC;GDSC;CCLE	10.919	Down-regulation
Other_PLK_PLK1_PLK1_ST	P38398	BRCA1	P53350	PLK1	S1551	L1558I	1558	Missense	distal	7	no	12.480	12.514	EPSD	COSMIC	10.919	Up-regulation
Other_PLK_PLK1_PLK1_ST	P38398	BRCA1	P53350	PLK1	S1551	L1547F	1547	Missense	distal	-4	no	12.480	12.355	EPSD	COSMIC	10.919	Down-regulation
Other_PLK_PLK1_PLK1_ST	P38398	BRCA1	P53350	PLK1	T1561	L1564P	1564	Missense	distal	3	no	10.899	11.067	EPSD	COSMIC	10.919	Gain
Other_PLK_PLK1_PLK1_ST	P38398	BRCA1	P53350	PLK1	T1561	P1562L	1562	Missense	proximal	1	no	10.899	11.744	EPSD	COSMIC	10.919	Gain
Other_PLK_PLK1_PLK1_ST	P38398	BRCA1	P53350	PLK1	T1561	S1566G	1566	Missense	distal	5	no	10.899	11.081	EPSD	COSMIC	10.919	Gain
Other_PLK_PLK1_PLK1_ST	P38398	BRCA1	P53350	PLK1	S1572	S1569G	1569	Missense	distal	-3	no	10.424	11.196	EPSD	COSMIC	10.919	Gain
Other_PLK_PLK1_PLK1_ST	P38398	BRCA1	P53350	PLK1	S1610	S1613G	1613	Missense	distal	3	no	11.176	11.179	EPSD	COSMIC	10.919	Up-regulation
Other_PLK_PLK1_PLK1_ST	P38398	BRCA1	P53350	PLK1	S1610	P1603T	1603	Missense	distal	-7	no	11.176	11.378	EPSD	COSMIC	10.919	Up-regulation
Other_PLK_PLK1_PLK1_ST	P38398	BRCA1	P53350	PLK1	S1610	A1608T	1608	Missense	proximal	-2	no	11.176	10.557	EPSD	COSMIC	10.919	Loss
Other_PLK_PLK1_PLK1_ST	P38398	BRCA1	P53350	PLK1	S1610	Q1612H	1612	Missense	proximal	2	no	11.176	11.554	EPSD	COSMIC	10.919	Up-regulation
Other_PLK_PLK1_PLK1_ST	P38398	BRCA1	P53350	PLK1	S1610	A1615V	1615	Missense	distal	5	no	11.176	10.438	EPSD	COSMIC	10.919	Loss
Other_PLK_PLK1_PLK1_ST	P38398	BRCA1	P53350	PLK1	S1610	V1607M	1607	Missense	distal	-3	no	11.176	11.304	EPSD	COSMIC	10.919	Up-regulation
Other_PLK_PLK1_PLK1_ST	P38398	BRCA1	P53350	PLK1	S1610	V1607E	1607	Missense	distal	-3	no	11.176	10.883	EPSD	COSMIC	10.919	Loss
Other_PLK_PLK1_PLK1_ST	P38398	BRCA1	P53350	PLK1	S1631	Y1625C	1625	Missense	distal	-6	no	12.214	11.864	EPSD	COSMIC	10.919	Down-regulation
Other_PLK_PLK1_PLK1_ST	P38398	BRCA1	P53350	PLK1	S1631	E1638V	1638	Missense	distal	7	no	12.214	12.285	EPSD	COSMIC	10.919	Up-regulation
Other_PLK_PLK1_PLK1_ST	P38398	BRCA1	P53350	PLK1	S1631	E1638D	1638	Missense	distal	7	no	12.214	12.210	EPSD	COSMIC	10.919	Down-regulation
Other_PLK_PLK1_PLK1_ST	P38398	BRCA1	P53350	PLK1	S1631	G1624W	1624	Missense	distal	-7	no	12.214	12.999	EPSD	COSMIC	10.919	Up-regulation
Other_PLK_PLK1_PLK1_ST	P38398	BRCA1	P53350	PLK1	S1631	E1635K	1635	Missense	distal	4	no	12.214	11.841	EPSD	COSMIC	10.919	Down-regulation
Other_PLK_PLK1_PLK1_ST	P38398	BRCA1	P53350	PLK1	S1651	M1652I	1652	Missense	proximal	1	no	11.995	11.030	EPSD	COSMIC	10.919	Down-regulation
Other_PLK_PLK1_PLK1_ST	P38398	BRCA1	P53350	PLK1	S1651	R1645T	1645	Missense	distal	-6	no	11.995	12.339	EPSD	COSMIC	10.919	Up-regulation
Other_PLK_PLK1_PLK1_ST	P38398	BRCA1	P53350	PLK1	S1651	R1645M	1645	Missense	distal	-6	no	11.995	12.324	EPSD	COSMIC	10.919	Up-regulation
Other_PLK_PLK1_PLK1_ST	P38398	BRCA1	P53350	PLK1	S1651	S1651F	1651	Missense	central	0	yes	11.995	0.000	EPSD	COSMIC	10.919	Loss
Other_PLK_PLK1_PLK1_ST	P38398	BRCA1	P53350	PLK1	S1651	R1645S	1645	Missense	distal	-6	no	11.995	12.442	EPSD	COSMIC	10.919	Up-regulation
Other_PLK_PLK1_PLK1_ST	P38398	BRCA1	P53350	PLK1	S1651	R1649T	1649	Missense	proximal	-2	no	11.995	11.682	EPSD	COSMIC	10.919	Down-regulation
Other_PLK_PLK1_PLK1_ST	P38398	BRCA1	P53350	PLK1	S1651	V1654E	1654	Missense	distal	3	no	11.995	12.023	EPSD	COSMIC	10.919	Up-regulation
Other_PLK_PLK1_PLK1_ST	P38398	BRCA1	P53350	PLK1	S1651	R1649I	1649	Missense	proximal	-2	no	11.995	11.656	EPSD	COSMIC	10.919	Down-regulation
Other_PLK_PLK1_PLK1_ST	P38398	BRCA1	P53350	PLK1	S1651	V1653A	1653	Missense	proximal	2	no	11.995	11.551	EPSD	COSMIC	10.919	Down-regulation
Other_PLK_PLK1_PLK1_ST	P38398	BRCA1	P53350	PLK1	S1651	R1649K	1649	Missense	proximal	-2	no	11.995	11.601	EPSD	COSMIC	10.919	Down-regulation
Other_PLK_PLK1_PLK1_ST	P38398	BRCA1	P53350	PLK1	S1651	V1654M	1654	Missense	distal	3	no	11.995	11.553	EPSD	COSMIC	10.919	Down-regulation
Other_PLK_PLK1_PLK1_ST	P38398	BRCA1	P53350	PLK1	T1700	C1697R	1697	Missense	distal	-3	no	10.164	10.960	EPSD	COSMIC	10.919	Gain
Other_PLK_PLK1_PLK1_ST	Q9BQQ3	GORASP1	P53350	PLK1	S189	G188R	188	Missense	proximal	-1	no	12.383	13.244	PhosphoSitePlus	COSMIC	10.919	Up-regulation
Other_PLK_PLK1_PLK1_ST	Q9BQQ3	GORASP1	P53350	PLK1	S241	S248P	248	Missense	distal	7	no	11.844	11.871	EPSD	COSMIC	10.919	Up-regulation
Other_PLK_PLK1_PLK1_ST	Q9BQQ3	GORASP1	P53350	PLK1	S274	P275L	275	Missense	proximal	1	no	10.530	11.376	EPSD	COSMIC	10.919	Gain
Other_PLK_PLK1_PLK1_ST	P51587	BRCA2	P53350	PLK1	S93	P89L	89	Missense	distal	-4	no	14.668	14.597	EPSD	COSMIC	10.919	Down-regulation
Other_PLK_PLK1_PLK1_ST	P51587	BRCA2	P53350	PLK1	S93	P94S	94	Missense	proximal	1	no	14.668	13.547	EPSD	COSMIC	10.919	Down-regulation
Other_PLK_PLK1_PLK1_ST	P51587	BRCA2	P53350	PLK1	S93	V95E	95	Missense	proximal	2	no	14.668	13.873	EPSD	COSMIC	10.919	Down-regulation
Other_PLK_PLK1_PLK1_ST	P51587	BRCA2	P53350	PLK1	S158	P153T	153	Missense	distal	-5	no	12.741	12.693	EPSD	COSMIC	10.919	Down-regulation
Other_PLK_PLK1_PLK1_ST	P51587	BRCA2	P53350	PLK1	S158	G162W	162	Missense	distal	4	no	12.741	12.421	EPSD	COSMIC	10.919	Down-regulation
Other_PLK_PLK1_PLK1_ST	P51587	BRCA2	P53350	PLK1	S158	V159L	159	Missense	proximal	1	no	12.741	13.140	EPSD	COSMIC	10.919	Up-regulation
Other_PLK_PLK1_PLK1_ST	P51587	BRCA2	P53350	PLK1	S158	R155T	155	Missense	distal	-3	no	12.741	12.285	EPSD	COSMIC	10.919	Down-regulation
Other_PLK_PLK1_PLK1_ST	P51587	BRCA2	P53350	PLK1	S193	S196R	196	Missense	distal	3	no	15.882	15.758	EPSD;PhosphoSitePlus	COSMIC	10.919	Down-regulation
Other_PLK_PLK1_PLK1_ST	P51587	BRCA2	P53350	PLK1	S193	P190H	190	Missense	distal	-3	no	15.882	16.459	EPSD;PhosphoSitePlus	COSMIC	10.919	Up-regulation
Other_PLK_PLK1_PLK1_ST	P51587	BRCA2	P53350	PLK1	S193	S196N	196	Missense	distal	3	no	15.882	15.927	EPSD;PhosphoSitePlus	COSMIC	10.919	Up-regulation
Other_PLK_PLK1_PLK1_ST	P51587	BRCA2	P53350	PLK1	S193	E187K	187	Missense	distal	-6	no	15.882	15.308	EPSD;PhosphoSitePlus	COSMIC	10.919	Down-regulation
Other_PLK_PLK1_PLK1_ST	P51587	BRCA2	P53350	PLK1	T203	S196R	196	Missense	distal	-7	no	12.549	12.052	EPSD;PhosphoSitePlus	COSMIC	10.919	Down-regulation
Other_PLK_PLK1_PLK1_ST	P51587	BRCA2	P53350	PLK1	T203	S196N	196	Missense	distal	-7	no	12.549	12.339	EPSD;PhosphoSitePlus	COSMIC	10.919	Down-regulation
Other_PLK_PLK1_PLK1_ST	P51587	BRCA2	P53350	PLK1	T203	P202L	202	Missense	proximal	-1	no	12.549	13.263	EPSD;PhosphoSitePlus	COSMIC	10.919	Up-regulation
Other_PLK_PLK1_PLK1_ST	P51587	BRCA2	P53350	PLK1	S205	P202L	202	Missense	distal	-3	no	10.065	11.257	EPSD;PhosphoSitePlus	COSMIC	10.919	Gain
Other_PLK_PLK1_PLK1_ST	P51587	BRCA2	P53350	PLK1	S239	H236Y	236	Missense	distal	-3	no	10.713	11.021	EPSD	COSMIC	10.919	Gain
Other_PLK_PLK1_PLK1_ST	P51587	BRCA2	P53350	PLK1	S239	Y232H	232	Missense	distal	-7	no	10.713	11.207	EPSD	COSMIC	10.919	Gain
Other_PLK_PLK1_PLK1_ST	P51587	BRCA2	P53350	PLK1	S253	T251A	251	Missense	proximal	-2	no	10.514	11.133	EPSD	COSMIC	10.919	Gain
Other_PLK_PLK1_PLK1_ST	P51587	BRCA2	P53350	PLK1	S273	G267R	267	Missense	distal	-6	no	11.890	11.988	EPSD	COSMIC	10.919	Up-regulation
Other_PLK_PLK1_PLK1_ST	P51587	BRCA2	P53350	PLK1	S273	V276A	276	Missense	distal	3	no	11.890	11.562	EPSD	COSMIC	10.919	Down-regulation
Other_PLK_PLK1_PLK1_ST	P51587	BRCA2	P53350	PLK1	T363	P365S	365	Missense	proximal	2	no	10.646	12.122	EPSD	COSMIC	10.919	Gain
Other_PLK_PLK1_PLK1_ST	P51587	BRCA2	P53350	PLK1	S445	I449F	449	Missense	distal	4	no	10.802	11.180	EPSD	COSMIC	10.919	Gain
Other_PLK_PLK1_PLK1_ST	P51587	BRCA2	P53350	PLK1	S445	R448H	448	Missense	distal	3	no	10.802	10.934	EPSD	COSMIC	10.919	Gain
Other_PLK_PLK1_PLK1_ST	P51587	BRCA2	P53350	PLK1	S445	F439V	439	Missense	distal	-6	no	10.802	11.045	EPSD	COSMIC	10.919	Gain
Other_PLK_PLK1_PLK1_ST	P51587	BRCA2	P53350	PLK1	S445	P447S	447	Missense	proximal	2	no	10.802	12.279	EPSD	COSMIC	10.919	Gain
Other_PLK_PLK1_PLK1_ST	P51587	BRCA2	P53350	PLK1	S497	S496F	496	Missense	proximal	-1	no	11.358	10.819	EPSD	COSMIC	10.919	Loss
Other_PLK_PLK1_PLK1_ST	P51587	BRCA2	P53350	PLK1	S497	P493S	493	Missense	distal	-4	no	11.358	11.480	EPSD	COSMIC	10.919	Up-regulation
Other_PLK_PLK1_PLK1_ST	P51587	BRCA2	P53350	PLK1	S519	M524T	524	Missense	distal	5	no	12.991	12.289	EPSD	COSMIC	10.919	Down-regulation
Other_PLK_PLK1_PLK1_ST	P51587	BRCA2	P53350	PLK1	S519	K513R	513	Missense	distal	-6	no	12.991	12.998	EPSD	COSMIC	10.919	Up-regulation
Other_PLK_PLK1_PLK1_ST	P51587	BRCA2	P53350	PLK1	S519	H523R	523	Missense	distal	4	no	12.991	12.567	EPSD	COSMIC	10.919	Down-regulation
Other_PLK_PLK1_PLK1_ST	P51587	BRCA2	P53350	PLK1	S648	P655R	655	Missense	distal	7	no	10.931	10.920	EPSD	COSMIC	10.919	Down-regulation
Other_PLK_PLK1_PLK1_ST	P51587	BRCA2	P53350	PLK1	S648	S652F	652	Missense	distal	4	no	10.931	10.118	EPSD	COSMIC	10.919	Loss
Other_PLK_PLK1_PLK1_ST	P51587	BRCA2	P53350	PLK1	S648	D651Y	651	Missense	distal	3	no	10.931	10.506	EPSD	COSMIC;CCLE	10.919	Loss
Other_PLK_PLK1_PLK1_ST	P51587	BRCA2	P53350	PLK1	S652	P655R	655	Missense	distal	3	no	12.192	12.047	EPSD	COSMIC	10.919	Down-regulation
Other_PLK_PLK1_PLK1_ST	P51587	BRCA2	P53350	PLK1	S652	S652F	652	Missense	central	0	yes	12.192	0.000	EPSD	COSMIC	10.919	Loss
Other_PLK_PLK1_PLK1_ST	P51587	BRCA2	P53350	PLK1	S652	D651Y	651	Missense	proximal	-1	no	12.192	11.735	EPSD	COSMIC;CCLE	10.919	Down-regulation
Other_PLK_PLK1_PLK1_ST	P51587	BRCA2	P53350	PLK1	T656	P655R	655	Missense	proximal	-1	no	12.455	12.693	EPSD	COSMIC	10.919	Up-regulation
Other_PLK_PLK1_PLK1_ST	P51587	BRCA2	P53350	PLK1	T656	S652F	652	Missense	distal	-4	no	12.455	12.137	EPSD	COSMIC	10.919	Down-regulation
Other_PLK_PLK1_PLK1_ST	P51587	BRCA2	P53350	PLK1	T656	F663S	663	Missense	distal	7	no	12.455	12.386	EPSD	COSMIC	10.919	Down-regulation
Other_PLK_PLK1_PLK1_ST	P51587	BRCA2	P53350	PLK1	T656	S661G	661	Missense	distal	5	no	12.455	12.638	EPSD	COSMIC	10.919	Up-regulation
Other_PLK_PLK1_PLK1_ST	P51587	BRCA2	P53350	PLK1	T656	D651Y	651	Missense	distal	-5	no	12.455	12.310	EPSD	COSMIC;CCLE	10.919	Down-regulation
Other_PLK_PLK1_PLK1_ST	P51587	BRCA2	P53350	PLK1	S683	Q684R	684	Missense	proximal	1	no	11.401	9.422	EPSD	COSMIC	10.919	Loss
Other_PLK_PLK1_PLK1_ST	P51587	BRCA2	P53350	PLK1	T768	T774A	774	Missense	distal	6	no	14.092	14.099	EPSD	COSMIC	10.919	Up-regulation
Other_PLK_PLK1_PLK1_ST	P51587	BRCA2	P53350	PLK1	T768	P773S	773	Missense	distal	5	no	14.092	13.705	EPSD	COSMIC	10.919	Down-regulation
Other_PLK_PLK1_PLK1_ST	P51587	BRCA2	P53350	PLK1	T768	P773T	773	Missense	distal	5	no	14.092	13.100	EPSD	COSMIC	10.919	Down-regulation
Other_PLK_PLK1_PLK1_ST	P51587	BRCA2	P53350	PLK1	T926	M927V	927	Missense	proximal	1	no	11.657	10.501	EPSD	COSMIC	10.919	Loss
Other_PLK_PLK1_PLK1_ST	P51587	BRCA2	P53350	PLK1	T926	V928A	928	Missense	proximal	2	no	11.657	11.214	EPSD	COSMIC	10.919	Down-regulation
Other_PLK_PLK1_PLK1_ST	P51587	BRCA2	P53350	PLK1	T926	P920S	920	Missense	distal	-6	no	11.657	12.281	EPSD	COSMIC	10.919	Up-regulation
Other_PLK_PLK1_PLK1_ST	P51587	BRCA2	P53350	PLK1	T933	A938E	938	Missense	distal	5	no	11.018	10.159	EPSD	COSMIC;GDSC;CCLE	10.919	Loss
Other_PLK_PLK1_PLK1_ST	P51587	BRCA2	P53350	PLK1	T933	M927V	927	Missense	distal	-6	no	11.018	10.861	EPSD	COSMIC	10.919	Loss
Other_PLK_PLK1_PLK1_ST	P51587	BRCA2	P53350	PLK1	T933	V928A	928	Missense	distal	-5	no	11.018	11.090	EPSD	COSMIC	10.919	Up-regulation
Other_PLK_PLK1_PLK1_ST	P51587	BRCA2	P53350	PLK1	T933	Q937K	937	Missense	distal	4	no	11.018	11.047	EPSD	COSMIC	10.919	Up-regulation
Other_PLK_PLK1_PLK1_ST	P51587	BRCA2	P53350	PLK1	T933	Q940H	940	Missense	distal	7	no	11.018	10.973	EPSD	COSMIC	10.919	Down-regulation
Other_PLK_PLK1_PLK1_ST	P51587	BRCA2	P53350	PLK1	S976	K981N	981	Missense	distal	5	no	11.705	11.382	EPSD	COSMIC;GDSC;CCLE	10.919	Down-regulation
Other_PLK_PLK1_PLK1_ST	P51587	BRCA2	P53350	PLK1	S976	Q969K	969	Missense	distal	-7	no	11.705	11.437	EPSD	COSMIC	10.919	Down-regulation
Other_PLK_PLK1_PLK1_ST	P51587	BRCA2	P53350	PLK1	S976	D980H	980	Missense	distal	4	no	11.705	11.181	EPSD	COSMIC	10.919	Down-regulation
Other_PLK_PLK1_PLK1_ST	P51587	BRCA2	P53350	PLK1	S976	L971S	971	Missense	distal	-5	no	11.705	11.041	EPSD	COSMIC	10.919	Down-regulation
Other_PLK_PLK1_PLK1_ST	P51587	BRCA2	P53350	PLK1	S976	I979M	979	Missense	distal	3	no	11.705	11.386	EPSD	COSMIC	10.919	Down-regulation
Other_PLK_PLK1_PLK1_ST	P51587	BRCA2	P53350	PLK1	S976	N978I	978	Missense	proximal	2	no	11.705	11.913	EPSD	COSMIC	10.919	Up-regulation
Other_PLK_PLK1_PLK1_ST	P51587	BRCA2	P53350	PLK1	S976	S976F	976	Missense	central	0	yes	11.705	0.000	EPSD	COSMIC;GDSC	10.919	Loss
Other_PLK_PLK1_PLK1_ST	P51587	BRCA2	P53350	PLK1	T1141	E1143D	1143	Missense	proximal	2	no	11.419	12.010	EPSD	COSMIC	10.919	Up-regulation
Other_PLK_PLK1_PLK1_ST	P51587	BRCA2	P53350	PLK1	T1141	T1141A	1141	Missense	central	0	yes	11.419	0.000	EPSD	COSMIC	10.919	Loss
Other_PLK_PLK1_PLK1_ST	P51587	BRCA2	P53350	PLK1	T1141	E1146G	1146	Missense	distal	5	no	11.419	11.894	EPSD	COSMIC	10.919	Up-regulation
Other_PLK_PLK1_PLK1_ST	P51587	BRCA2	P53350	PLK1	T1282	N1287K	1287	Missense	distal	5	no	10.693	11.017	EPSD	COSMIC	10.919	Gain
Other_PLK_PLK1_PLK1_ST	P51587	BRCA2	P53350	PLK1	S1770	S1764L	1764	Missense	distal	-6	no	11.341	11.006	EPSD	COSMIC	10.919	Down-regulation
Other_PLK_PLK1_PLK1_ST	P51587	BRCA2	P53350	PLK1	S1770	S1770F	1770	Missense	central	0	yes	11.341	0.000	EPSD	COSMIC	10.919	Loss
Other_PLK_PLK1_PLK1_ST	P51587	BRCA2	P53350	PLK1	S1770	G1771D	1771	Missense	proximal	1	no	11.341	11.338	EPSD	COSMIC	10.919	Down-regulation
Other_PLK_PLK1_PLK1_ST	P51587	BRCA2	P53350	PLK1	S1770	D1769H	1769	Missense	proximal	-1	no	11.341	10.609	EPSD	COSMIC	10.919	Loss
Other_PLK_PLK1_PLK1_ST	P51587	BRCA2	P53350	PLK1	S1786	E1780K	1780	Missense	distal	-6	no	16.155	15.581	EPSD	COSMIC	10.919	Down-regulation
Other_PLK_PLK1_PLK1_ST	P51587	BRCA2	P53350	PLK1	S1869	V1873I	1873	Missense	distal	4	no	11.617	10.888	EPSD	COSMIC	10.919	Loss
Other_PLK_PLK1_PLK1_ST	P51587	BRCA2	P53350	PLK1	S1869	D1868Y	1868	Missense	proximal	-1	no	11.617	11.160	EPSD	COSMIC	10.919	Down-regulation
Other_PLK_PLK1_PLK1_ST	P51587	BRCA2	P53350	PLK1	S1869	F1870Y	1870	Missense	proximal	1	no	11.617	9.307	EPSD	COSMIC	10.919	Loss
Other_PLK_PLK1_PLK1_ST	P51587	BRCA2	P53350	PLK1	S1869	F1870L	1870	Missense	proximal	1	no	11.617	10.536	EPSD	COSMIC	10.919	Loss
Other_PLK_PLK1_PLK1_ST	P51587	BRCA2	P53350	PLK1	S1951	S1946L	1946	Missense	distal	-5	no	12.018	12.682	EPSD	COSMIC	10.919	Up-regulation
Other_PLK_PLK1_PLK1_ST	P51587	BRCA2	P53350	PLK1	S1951	I1957V	1957	Missense	distal	6	no	12.018	12.124	EPSD	COSMIC	10.919	Up-regulation
Other_PLK_PLK1_PLK1_ST	P51587	BRCA2	P53350	PLK1	S1955	C1960Y	1960	Missense	distal	5	no	12.341	12.054	EPSD	COSMIC	10.919	Down-regulation
Other_PLK_PLK1_PLK1_ST	P51587	BRCA2	P53350	PLK1	S1955	I1957V	1957	Missense	proximal	2	no	12.341	12.123	EPSD	COSMIC	10.919	Down-regulation
Other_PLK_PLK1_PLK1_ST	P51587	BRCA2	P53350	PLK1	S1955	C1960G	1960	Missense	distal	5	no	12.341	12.394	EPSD	COSMIC	10.919	Up-regulation
Other_PLK_PLK1_PLK1_ST	P51587	BRCA2	P53350	PLK1	S2072	L2069S	2069	Missense	distal	-3	no	12.906	12.132	EPSD	COSMIC	10.919	Down-regulation
Other_PLK_PLK1_PLK1_ST	P51587	BRCA2	P53350	PLK1	S2091	S2095L	2095	Missense	distal	4	no	12.331	11.719	EPSD	COSMIC	10.919	Down-regulation
Other_PLK_PLK1_PLK1_ST	P51587	BRCA2	P53350	PLK1	S2091	P2096L	2096	Missense	distal	5	no	12.331	11.598	EPSD	COSMIC	10.919	Down-regulation
Other_PLK_PLK1_PLK1_ST	P51587	BRCA2	P53350	PLK1	S2095	P2096L	2096	Missense	proximal	1	no	10.245	11.091	EPSD	COSMIC	10.919	Gain
Other_PLK_PLK1_PLK1_ST	P51587	BRCA2	P53350	PLK1	T2681	R2678S	2678	Missense	distal	-3	no	11.492	10.660	EPSD	COSMIC	10.919	Loss
Other_PLK_PLK1_PLK1_ST	P51587	BRCA2	P53350	PLK1	T2681	T2681P	2681	Missense	central	0	yes	11.492	0.000	EPSD	COSMIC	10.919	Loss
Other_PLK_PLK1_PLK1_ST	P51587	BRCA2	P53350	PLK1	T2681	K2684I	2684	Missense	distal	3	no	11.492	11.547	EPSD	COSMIC	10.919	Up-regulation
Other_PLK_PLK1_PLK1_ST	P51587	BRCA2	P53350	PLK1	T2681	V2687F	2687	Missense	distal	6	no	11.492	10.808	EPSD	COSMIC	10.919	Loss
Other_PLK_PLK1_PLK1_ST	P51587	BRCA2	P53350	PLK1	T2681	E2677K	2677	Missense	distal	-4	no	11.492	11.109	EPSD	COSMIC	10.919	Down-regulation
Other_PLK_PLK1_PLK1_ST	P51587	BRCA2	P53350	PLK1	T2685	R2678S	2678	Missense	distal	-7	no	10.738	11.235	EPSD	COSMIC	10.919	Gain
Other_PLK_PLK1_PLK1_ST	P51587	BRCA2	P53350	PLK1	T2685	T2681P	2681	Missense	distal	-4	no	10.738	10.979	EPSD	COSMIC	10.919	Gain
Other_PLK_PLK1_PLK1_ST	P51587	BRCA2	P53350	PLK1	T2685	K2684I	2684	Missense	proximal	-1	no	10.738	11.330	EPSD	COSMIC	10.919	Gain
Other_PLK_PLK1_PLK1_ST	P51587	BRCA2	P53350	PLK1	S2695	S2701Y	2701	Missense	distal	6	no	10.982	10.454	EPSD	COSMIC	10.919	Loss
Other_PLK_PLK1_PLK1_ST	P51587	BRCA2	P53350	PLK1	S2695	N2699D	2699	Missense	distal	4	no	10.982	11.221	EPSD	COSMIC	10.919	Up-regulation
Other_PLK_PLK1_PLK1_ST	P51587	BRCA2	P53350	PLK1	S2695	A2698T	2698	Missense	distal	3	no	10.982	11.021	EPSD	COSMIC	10.919	Up-regulation
Other_PLK_PLK1_PLK1_ST	P51587	BRCA2	P53350	PLK1	S2695	N2699K	2699	Missense	distal	4	no	10.982	10.833	EPSD	COSMIC	10.919	Loss
Other_PLK_PLK1_PLK1_ST	P51587	BRCA2	P53350	PLK1	S2695	S2691F	2691	Missense	distal	-4	no	10.982	10.664	EPSD	COSMIC	10.919	Loss
Other_PLK_PLK1_PLK1_ST	P51587	BRCA2	P53350	PLK1	S2697	S2701Y	2701	Missense	distal	4	no	11.231	10.988	EPSD	COSMIC	10.919	Down-regulation
Other_PLK_PLK1_PLK1_ST	P51587	BRCA2	P53350	PLK1	S2697	N2699D	2699	Missense	proximal	2	no	11.231	11.016	EPSD	COSMIC	10.919	Down-regulation
Other_PLK_PLK1_PLK1_ST	P51587	BRCA2	P53350	PLK1	S2697	A2698T	2698	Missense	proximal	1	no	11.231	11.693	EPSD	COSMIC	10.919	Up-regulation
Other_PLK_PLK1_PLK1_ST	P51587	BRCA2	P53350	PLK1	S2697	N2699K	2699	Missense	proximal	2	no	11.231	10.256	EPSD	COSMIC	10.919	Loss
Other_PLK_PLK1_PLK1_ST	P51587	BRCA2	P53350	PLK1	S2697	S2691F	2691	Missense	distal	-6	no	11.231	10.713	EPSD	COSMIC	10.919	Loss
Other_PLK_PLK1_PLK1_ST	P51587	BRCA2	P53350	PLK1	S2701	S2701Y	2701	Missense	central	0	yes	12.697	0.000	EPSD	COSMIC	10.919	Loss
Other_PLK_PLK1_PLK1_ST	P51587	BRCA2	P53350	PLK1	S2701	N2699D	2699	Missense	proximal	-2	no	12.697	13.940	EPSD	COSMIC	10.919	Up-regulation
Other_PLK_PLK1_PLK1_ST	P51587	BRCA2	P53350	PLK1	S2701	A2698T	2698	Missense	distal	-3	no	12.697	12.552	EPSD	COSMIC	10.919	Down-regulation
Other_PLK_PLK1_PLK1_ST	P51587	BRCA2	P53350	PLK1	S2701	N2699K	2699	Missense	proximal	-2	no	12.697	10.669	EPSD	COSMIC	10.919	Loss
Other_PLK_PLK1_PLK1_ST	P51587	BRCA2	P53350	PLK1	S3284	C3287S	3287	Missense	distal	3	no	11.046	11.110	EPSD	COSMIC	10.919	Up-regulation
Other_PLK_PLK1_PLK1_ST	P51587	BRCA2	P53350	PLK1	S3284	C3287Y	3287	Missense	distal	3	no	11.046	10.930	EPSD	COSMIC	10.919	Down-regulation
Other_PLK_PLK1_PLK1_ST	P51587	BRCA2	P53350	PLK1	S3284	P3282L	3282	Missense	proximal	-2	no	11.046	10.682	EPSD	COSMIC	10.919	Loss
Other_PLK_PLK1_PLK1_ST	P51587	BRCA2	P53350	PLK1	S3284	L3277P	3277	Missense	distal	-7	no	11.046	11.140	EPSD	COSMIC	10.919	Up-regulation
Other_PLK_PLK1_PLK1_ST	P51587	BRCA2	P53350	PLK1	S3284	P3285L	3285	Missense	proximal	1	no	11.046	11.891	EPSD	COSMIC	10.919	Up-regulation
Other_PLK_PLK1_PLK1_ST	P51587	BRCA2	P53350	PLK1	T3288	C3287S	3287	Missense	proximal	-1	no	9.149	11.010	EPSD	COSMIC	10.919	Gain
Other_PLK_PLK1_PLK1_ST	P51587	BRCA2	P53350	PLK1	T3288	C3287Y	3287	Missense	proximal	-1	no	9.149	11.345	EPSD	COSMIC	10.919	Gain
Other_PLK_PLK1_PLK1_ST	P51587	BRCA2	P53350	PLK1	S3397	S3397F	3397	Missense	central	0	yes	15.307	0.000	EPSD	COSMIC	10.919	Loss
Other_PLK_PLK1_PLK1_ST	P51587	BRCA2	P53350	PLK1	S3397	S3400C	3400	Missense	distal	3	no	15.307	15.243	EPSD	COSMIC	10.919	Down-regulation
Other_PLK_PLK1_PLK1_ST	P51587	BRCA2	P53350	PLK1	S3397	C3404S	3404	Missense	distal	7	no	15.307	15.239	EPSD	COSMIC	10.919	Down-regulation
Other_PLK_PLK1_PLK1_ST	Q38SD2	LRRK1	P53350	PLK1	S784	C782Y	782	Missense	proximal	-2	no	9.834	13.344	EPSD	COSMIC	10.919	Gain
Other_PLK_PLK1_PLK1_ST	Q38SD2	LRRK1	P53350	PLK1	S1064	K1059R	1059	Missense	distal	-5	no	10.593	11.131	EPSD	COSMIC	10.919	Gain
Other_PLK_PLK1_PLK1_ST	Q38SD2	LRRK1	P53350	PLK1	S1100	F1094S	1094	Missense	distal	-6	no	10.469	10.987	EPSD	COSMIC	10.919	Gain
Other_PLK_PLK1_PLK1_ST	Q38SD2	LRRK1	P53350	PLK1	S1100	G1096W	1096	Missense	distal	-4	no	10.469	10.972	EPSD	COSMIC	10.919	Gain
Other_PLK_PLK1_PLK1_ST	Q38SD2	LRRK1	P53350	PLK1	S1103	G1096W	1096	Missense	distal	-7	no	10.580	11.365	EPSD	COSMIC	10.919	Gain
Other_PLK_PLK1_PLK1_ST	Q38SD2	LRRK1	P53350	PLK1	S1241	S1241I	1241	Missense	central	0	yes	11.615	0.000	EPSD	COSMIC	10.919	Loss
Other_PLK_PLK1_PLK1_ST	Q38SD2	LRRK1	P53350	PLK1	S1241	E1239G	1239	Missense	proximal	-2	no	11.615	8.687	EPSD	COSMIC	10.919	Loss
Other_PLK_PLK1_PLK1_ST	Q38SD2	LRRK1	P53350	PLK1	S1241	L1238V	1238	Missense	distal	-3	no	11.615	10.965	EPSD	COSMIC	10.919	Down-regulation
Other_PLK_PLK1_PLK1_ST	Q38SD2	LRRK1	P53350	PLK1	S1241	E1239K	1239	Missense	proximal	-2	no	11.615	8.738	EPSD	COSMIC	10.919	Loss
Other_PLK_PLK1_PLK1_ST	Q38SD2	LRRK1	P53350	PLK1	S1241	V1247I	1247	Missense	distal	6	no	11.615	11.509	EPSD	COSMIC	10.919	Down-regulation
Other_PLK_PLK1_PLK1_ST	Q38SD2	LRRK1	P53350	PLK1	S1246	S1241I	1241	Missense	distal	-5	no	10.899	11.268	EPSD	COSMIC	10.919	Gain
Other_PLK_PLK1_PLK1_ST	Q38SD2	LRRK1	P53350	PLK1	S1246	V1247I	1247	Missense	proximal	1	no	10.899	11.091	EPSD	COSMIC	10.919	Gain
Other_PLK_PLK1_PLK1_ST	Q38SD2	LRRK1	P53350	PLK1	S1246	G1249V	1249	Missense	distal	3	no	10.899	11.048	EPSD	COSMIC	10.919	Gain
Other_PLK_PLK1_PLK1_ST	Q38SD2	LRRK1	P53350	PLK1	S1302	S1302F	1302	Missense	central	0	yes	11.509	0.000	EPSD	COSMIC	10.919	Loss
Other_PLK_PLK1_PLK1_ST	Q38SD2	LRRK1	P53350	PLK1	S1302	R1305L	1305	Missense	distal	3	no	11.509	11.486	EPSD	COSMIC	10.919	Down-regulation
Other_PLK_PLK1_PLK1_ST	Q38SD2	LRRK1	P53350	PLK1	S1302	A1297V	1297	Missense	distal	-5	no	11.509	11.436	EPSD	COSMIC	10.919	Down-regulation
Other_PLK_PLK1_PLK1_ST	Q38SD2	LRRK1	P53350	PLK1	S1302	E1303K	1303	Missense	proximal	1	no	11.509	11.058	EPSD	COSMIC	10.919	Down-regulation
Other_PLK_PLK1_PLK1_ST	Q38SD2	LRRK1	P53350	PLK1	S1817	D1815H	1815	Missense	proximal	-2	no	13.695	10.508	PhosphoSitePlus	COSMIC	10.919	Loss
Other_PLK_PLK1_PLK1_ST	Q38SD2	LRRK1	P53350	PLK1	S1817	A1814T	1814	Missense	distal	-3	no	13.695	13.549	PhosphoSitePlus	COSMIC	10.919	Down-regulation
Other_PLK_PLK1_PLK1_ST	Q38SD2	LRRK1	P53350	PLK1	S1817	I1813T	1813	Missense	distal	-4	no	13.695	13.299	PhosphoSitePlus	COSMIC	10.919	Down-regulation
Other_PLK_PLK1_PLK1_ST	Q38SD2	LRRK1	P53350	PLK1	S1817	E1822D	1822	Missense	distal	5	no	13.695	14.136	PhosphoSitePlus	COSMIC	10.919	Up-regulation
Other_PLK_PLK1_PLK1_ST	Q38SD2	LRRK1	P53350	PLK1	S1817	A1814V	1814	Missense	distal	-3	no	13.695	13.296	PhosphoSitePlus	COSMIC	10.919	Down-regulation
Other_PLK_PLK1_PLK1_ST	Q9UBB4	ATXN10	P53350	PLK1	S364	I363V	363	Missense	proximal	-1	no	12.850	11.876	EPSD	COSMIC	10.919	Down-regulation
Other_PLK_PLK1_PLK1_ST	Q9UBB4	ATXN10	P53350	PLK1	S364	N365S	365	Missense	proximal	1	no	12.850	12.110	EPSD	COSMIC	10.919	Down-regulation
Other_PLK_PLK1_PLK1_ST	Q9UBB4	ATXN10	P53350	PLK1	S364	V357G	357	Missense	distal	-7	no	12.850	12.451	EPSD	COSMIC	10.919	Down-regulation
Other_PLK_PLK1_PLK1_ST	Q9UBB4	ATXN10	P53350	PLK1	S364	N368S	368	Missense	distal	4	no	12.850	13.086	EPSD	COSMIC	10.919	Up-regulation
Other_PLK_PLK1_PLK1_ST	Q9UBB4	ATXN10	P53350	PLK1	T426	S430N	430	Missense	distal	4	no	11.561	11.325	EPSD	COSMIC	10.919	Down-regulation
Other_PLK_PLK1_PLK1_ST	Q9UBB4	ATXN10	P53350	PLK1	S430	S430N	430	Missense	central	0	yes	10.958	0.000	EPSD	COSMIC	10.919	Loss
Other_PLK_PLK1_PLK1_ST	Q9UBB4	ATXN10	P53350	PLK1	S448	A445V	445	Missense	distal	-3	no	15.036	14.638	EPSD	COSMIC	10.919	Down-regulation
Other_PLK_PLK1_PLK1_ST	Q9UBB4	ATXN10	P53350	PLK1	S448	D446N	446	Missense	proximal	-2	no	15.036	13.794	EPSD	COSMIC	10.919	Down-regulation
Other_PLK_PLK1_PLK1_ST	Q9H0H5	RACGAP1	P53350	PLK1	S66	D69N	69	Missense	distal	3	no	12.638	12.438	EPSD	COSMIC	10.919	Down-regulation
Other_PLK_PLK1_PLK1_ST	Q9H0H5	RACGAP1	P53350	PLK1	T272	T277M	277	Missense	distal	5	no	10.648	11.350	EPSD	COSMIC	10.919	Gain
Other_PLK_PLK1_PLK1_ST	Q9H0H5	RACGAP1	P53350	PLK1	S559	P565S	565	Missense	distal	6	no	11.296	11.152	EPSD	COSMIC	10.919	Down-regulation
Other_PLK_PLK1_PLK1_ST	Q9H0H5	RACGAP1	P53350	PLK1	S573	T579I	579	Missense	distal	6	no	11.287	11.012	EPSD	COSMIC	10.919	Down-regulation
Other_PLK_PLK1_PLK1_ST	Q9H0H5	RACGAP1	P53350	PLK1	T588	P589F	589	Missense	proximal	1	no	9.099	11.026	EPSD	COSMIC	10.919	Gain
Other_PLK_PLK1_PLK1_ST	Q9H0H5	RACGAP1	P53350	PLK1	S593	P589F	589	Missense	distal	-4	no	11.836	11.639	EPSD	COSMIC	10.919	Down-regulation
Other_PLK_PLK1_PLK1_ST	Q9H0H5	RACGAP1	P53350	PLK1	S593	R599C	599	Missense	distal	6	no	11.836	11.210	EPSD	COSMIC	10.919	Down-regulation
Other_PLK_PLK1_PLK1_ST	Q9H0H5	RACGAP1	P53350	PLK1	T606	R599C	599	Missense	distal	-7	no	11.098	10.978	EPSD	COSMIC	10.919	Down-regulation
Other_PLK_PLK1_PLK1_ST	O95251	KAT7	P53350	PLK1	S18	S21P	21	Missense	distal	3	no	14.690	14.712	EPSD	COSMIC;GDSC;CCLE	10.919	Up-regulation
Other_PLK_PLK1_PLK1_ST	O95251	KAT7	P53350	PLK1	S18	S12L	12	Missense	distal	-6	no	14.690	14.356	EPSD	COSMIC	10.919	Down-regulation
Other_PLK_PLK1_PLK1_ST	O95251	KAT7	P53350	PLK1	S21	S21P	21	Missense	central	0	yes	12.134	0.000	EPSD	COSMIC;GDSC;CCLE	10.919	Loss
Other_PLK_PLK1_PLK1_ST	O95251	KAT7	P53350	PLK1	T27	S21P	21	Missense	distal	-6	no	13.898	13.275	EPSD	COSMIC;GDSC;CCLE	10.919	Down-regulation
Other_PLK_PLK1_PLK1_ST	O95251	KAT7	P53350	PLK1	S52	P58S	58	Missense	distal	6	no	13.226	13.082	EPSD	COSMIC	10.919	Down-regulation
Other_PLK_PLK1_PLK1_ST	O95251	KAT7	P53350	PLK1	S57	P58S	58	Missense	proximal	1	no	13.232	12.110	PhosphoSitePlus	COSMIC	10.919	Down-regulation
Other_PLK_PLK1_PLK1_ST	O95251	KAT7	P53350	PLK1	S102	G101D	101	Missense	proximal	-1	no	9.692	12.281	EPSD	COSMIC	10.919	Gain
Other_PLK_PLK1_PLK1_ST	O95251	KAT7	P53350	PLK1	S111	D109G	109	Missense	proximal	-2	no	11.300	7.978	EPSD	COSMIC	10.919	Loss
Other_PLK_PLK1_PLK1_ST	O95251	KAT7	P53350	PLK1	S124	E123D	123	Missense	proximal	-1	no	12.875	13.672	EPSD	COSMIC	10.919	Up-regulation
Other_PLK_PLK1_PLK1_ST	O95251	KAT7	P53350	PLK1	S152	M157T	157	Missense	distal	5	no	12.663	11.962	EPSD	COSMIC;CCLE	10.919	Down-regulation
Other_PLK_PLK1_PLK1_ST	O95251	KAT7	P53350	PLK1	S152	M157V	157	Missense	distal	5	no	12.663	12.395	EPSD	COSMIC	10.919	Down-regulation
Other_PLK_PLK1_PLK1_ST	O95251	KAT7	P53350	PLK1	S158	M157T	157	Missense	proximal	-1	no	17.801	16.982	EPSD	COSMIC;CCLE	10.919	Down-regulation
Other_PLK_PLK1_PLK1_ST	O95251	KAT7	P53350	PLK1	S158	M157V	157	Missense	proximal	-1	no	17.801	16.772	EPSD	COSMIC	10.919	Down-regulation
Other_PLK_PLK1_PLK1_ST	O95251	KAT7	P53350	PLK1	S405	R400G	400	Missense	distal	-5	no	11.138	10.853	EPSD	COSMIC	10.919	Loss
Other_PLK_PLK1_PLK1_ST	O95251	KAT7	P53350	PLK1	S405	I404V	404	Missense	proximal	-1	no	11.138	10.164	EPSD	COSMIC;CCLE	10.919	Loss
Other_PLK_PLK1_PLK1_ST	O95251	KAT7	P53350	PLK1	S405	R400C	400	Missense	distal	-5	no	11.138	10.473	EPSD	COSMIC	10.919	Loss
Other_PLK_PLK1_PLK1_ST	O95251	KAT7	P53350	PLK1	S545	A549F	549	Missense	distal	4	no	11.990	11.374	EPSD	COSMIC	10.919	Down-regulation
Other_PLK_PLK1_PLK1_ST	O95251	KAT7	P53350	PLK1	S601	P600S	600	Missense	proximal	-1	no	9.846	11.020	EPSD	COSMIC	10.919	Gain
Other_PLK_PLK1_PLK1_ST	Q13127	REST	P53350	PLK1	S96	D98E	98	Missense	proximal	2	no	11.172	10.581	EPSD	COSMIC	10.919	Loss
Other_PLK_PLK1_PLK1_ST	Q13127	REST	P53350	PLK1	S96	P103L	103	Missense	distal	7	no	11.172	11.143	EPSD	COSMIC	10.919	Down-regulation
Other_PLK_PLK1_PLK1_ST	Q13127	REST	P53350	PLK1	S201	S201F	201	Missense	central	0	yes	13.019	0.000	EPSD	COSMIC	10.919	Loss
Other_PLK_PLK1_PLK1_ST	Q13127	REST	P53350	PLK1	S201	A206P	206	Missense	distal	5	no	13.019	12.839	EPSD	COSMIC	10.919	Down-regulation
Other_PLK_PLK1_PLK1_ST	Q13127	REST	P53350	PLK1	S201	S203F	203	Missense	proximal	2	no	13.019	12.468	EPSD	COSMIC	10.919	Down-regulation
Other_PLK_PLK1_PLK1_ST	Q13127	REST	P53350	PLK1	S201	T205P	205	Missense	distal	4	no	13.019	12.890	EPSD	COSMIC	10.919	Down-regulation
Other_PLK_PLK1_PLK1_ST	Q13127	REST	P53350	PLK1	S204	S201F	201	Missense	distal	-3	no	13.943	13.314	EPSD	COSMIC	10.919	Down-regulation
Other_PLK_PLK1_PLK1_ST	Q13127	REST	P53350	PLK1	S204	A206P	206	Missense	proximal	2	no	13.943	12.706	EPSD	COSMIC	10.919	Down-regulation
Other_PLK_PLK1_PLK1_ST	Q13127	REST	P53350	PLK1	S204	S203F	203	Missense	proximal	-1	no	13.943	13.404	EPSD	COSMIC	10.919	Down-regulation
Other_PLK_PLK1_PLK1_ST	Q13127	REST	P53350	PLK1	S204	T205P	205	Missense	proximal	1	no	13.943	14.472	EPSD	COSMIC	10.919	Up-regulation
Other_PLK_PLK1_PLK1_ST	Q13127	REST	P53350	PLK1	S555	K560T	560	Missense	distal	5	no	11.914	11.590	EPSD	COSMIC	10.919	Down-regulation
Other_PLK_PLK1_PLK1_ST	Q13127	REST	P53350	PLK1	S555	S549R	549	Missense	distal	-6	no	11.914	11.466	EPSD	COSMIC	10.919	Down-regulation
Other_PLK_PLK1_PLK1_ST	Q13127	REST	P53350	PLK1	S555	G561S	561	Missense	distal	6	no	11.914	12.118	EPSD	COSMIC	10.919	Up-regulation
Other_PLK_PLK1_PLK1_ST	Q13127	REST	P53350	PLK1	S563	G561S	561	Missense	proximal	-2	no	10.433	11.103	EPSD	COSMIC	10.919	Gain
Other_PLK_PLK1_PLK1_ST	Q13127	REST	P53350	PLK1	S782	P776A	776	Missense	distal	-6	no	11.384	11.972	EPSD	COSMIC	10.919	Up-regulation
Other_PLK_PLK1_PLK1_ST	Q13127	REST	P53350	PLK1	S861	L860I	860	Missense	proximal	-1	no	10.609	11.085	EPSD	COSMIC	10.919	Gain
Other_PLK_PLK1_PLK1_ST	Q13127	REST	P53350	PLK1	S942	E946K	946	Missense	distal	4	no	14.159	13.785	EPSD	COSMIC	10.919	Down-regulation
Other_PLK_PLK1_PLK1_ST	Q13127	REST	P53350	PLK1	S942	G936C	936	Missense	distal	-6	no	14.159	13.502	EPSD	COSMIC	10.919	Down-regulation
Other_PLK_PLK1_PLK1_ST	P30622	CLIP1	P53350	PLK1	T36	S43N	43	Missense	distal	7	no	12.108	12.164	EPSD	COSMIC	10.919	Up-regulation
Other_PLK_PLK1_PLK1_ST	P30622	CLIP1	P53350	PLK1	T36	K35N	35	Missense	proximal	-1	no	12.108	12.543	EPSD	COSMIC	10.919	Up-regulation
Other_PLK_PLK1_PLK1_ST	P30622	CLIP1	P53350	PLK1	S147	T153M	153	Missense	distal	6	no	11.257	10.727	EPSD	COSMIC;GDSC;CCLE	10.919	Loss
Other_PLK_PLK1_PLK1_ST	P30622	CLIP1	P53350	PLK1	S180	T182M	182	Missense	proximal	2	no	10.736	11.375	EPSD	COSMIC	10.919	Gain
Other_PLK_PLK1_PLK1_ST	P30622	CLIP1	P53350	PLK1	S180	P179T	179	Missense	proximal	-1	no	10.736	11.163	EPSD	COSMIC	10.919	Gain
Other_PLK_PLK1_PLK1_ST	P30622	CLIP1	P53350	PLK1	S200	I196V	196	Missense	distal	-4	no	14.269	14.135	EPSD	COSMIC	10.919	Down-regulation
Other_PLK_PLK1_PLK1_ST	P30622	CLIP1	P53350	PLK1	S200	S193G	193	Missense	distal	-7	no	14.269	13.572	EPSD	COSMIC	10.919	Down-regulation
Other_PLK_PLK1_PLK1_ST	P30622	CLIP1	P53350	PLK1	T260	R261M	261	Missense	proximal	1	no	8.481	12.369	EPSD	COSMIC	10.919	Gain
Other_PLK_PLK1_PLK1_ST	P30622	CLIP1	P53350	PLK1	T302	V299L	299	Missense	distal	-3	no	11.554	12.204	EPSD	COSMIC	10.919	Up-regulation
Other_PLK_PLK1_PLK1_ST	P30622	CLIP1	P53350	PLK1	T302	T303M	303	Missense	proximal	1	no	11.554	13.686	EPSD	COSMIC	10.919	Up-regulation
Other_PLK_PLK1_PLK1_ST	P30622	CLIP1	P53350	PLK1	T302	V299M	299	Missense	distal	-3	no	11.554	11.682	EPSD	COSMIC	10.919	Up-regulation
Other_PLK_PLK1_PLK1_ST	P30622	CLIP1	P53350	PLK1	T302	A301V	301	Missense	proximal	-1	no	11.554	11.064	EPSD	COSMIC	10.919	Down-regulation
Other_PLK_PLK1_PLK1_ST	P30622	CLIP1	P53350	PLK1	T302	A301T	301	Missense	proximal	-1	no	11.554	11.274	EPSD	COSMIC;CCLE	10.919	Down-regulation
Other_PLK_PLK1_PLK1_ST	P30622	CLIP1	P53350	PLK1	S306	V299L	299	Missense	distal	-7	no	11.868	11.860	EPSD	COSMIC	10.919	Down-regulation
Other_PLK_PLK1_PLK1_ST	P30622	CLIP1	P53350	PLK1	S306	T303M	303	Missense	distal	-3	no	11.868	11.743	EPSD	COSMIC	10.919	Down-regulation
Other_PLK_PLK1_PLK1_ST	P30622	CLIP1	P53350	PLK1	S306	V299M	299	Missense	distal	-7	no	11.868	11.735	EPSD	COSMIC	10.919	Down-regulation
Other_PLK_PLK1_PLK1_ST	P30622	CLIP1	P53350	PLK1	S306	A301V	301	Missense	distal	-5	no	11.868	11.795	EPSD	COSMIC	10.919	Down-regulation
Other_PLK_PLK1_PLK1_ST	P30622	CLIP1	P53350	PLK1	S306	A301T	301	Missense	distal	-5	no	11.868	11.799	EPSD	COSMIC;CCLE	10.919	Down-regulation
Other_PLK_PLK1_PLK1_ST	P30622	CLIP1	P53350	PLK1	S325	P330L	330	Missense	distal	5	no	12.340	11.606	EPSD	COSMIC	10.919	Down-regulation
Other_PLK_PLK1_PLK1_ST	P30622	CLIP1	P53350	PLK1	S340	R342H	342	Missense	proximal	2	no	10.570	11.273	EPSD	COSMIC;CCLE	10.919	Gain
Other_PLK_PLK1_PLK1_ST	P30622	CLIP1	P53350	PLK1	S383	T382P	382	Missense	proximal	-1	no	11.438	11.011	EPSD	COSMIC	10.919	Down-regulation
Other_PLK_PLK1_PLK1_ST	P30622	CLIP1	P53350	PLK1	S383	E387Q	387	Missense	distal	4	no	11.438	11.034	EPSD	COSMIC	10.919	Down-regulation
Other_PLK_PLK1_PLK1_ST	P30622	CLIP1	P53350	PLK1	S449	G453A	453	Missense	distal	4	no	12.366	12.252	EPSD	COSMIC	10.919	Down-regulation
Other_PLK_PLK1_PLK1_ST	P30622	CLIP1	P53350	PLK1	S449	R444W	444	Missense	distal	-5	no	12.366	12.133	EPSD	COSMIC	10.919	Down-regulation
Other_PLK_PLK1_PLK1_ST	P30622	CLIP1	P53350	PLK1	S449	E456K	456	Missense	distal	7	no	12.366	12.439	EPSD	COSMIC	10.919	Up-regulation
Other_PLK_PLK1_PLK1_ST	P30622	CLIP1	P53350	PLK1	T501	E497V	497	Missense	distal	-4	no	11.595	11.504	EPSD	COSMIC	10.919	Down-regulation
Other_PLK_PLK1_PLK1_ST	P30622	CLIP1	P53350	PLK1	T501	S507G	507	Missense	distal	6	no	11.595	11.390	EPSD	COSMIC	10.919	Down-regulation
Other_PLK_PLK1_PLK1_ST	P30622	CLIP1	P53350	PLK1	T505	S507G	507	Missense	proximal	2	no	11.629	10.048	EPSD	COSMIC	10.919	Loss
Other_PLK_PLK1_PLK1_ST	P30622	CLIP1	P53350	PLK1	T505	R511H	511	Missense	distal	6	no	11.629	11.413	EPSD	COSMIC	10.919	Down-regulation
Other_PLK_PLK1_PLK1_ST	P30622	CLIP1	P53350	PLK1	T505	R511C	511	Missense	distal	6	no	11.629	11.003	EPSD	COSMIC	10.919	Down-regulation
Other_PLK_PLK1_PLK1_ST	P30622	CLIP1	P53350	PLK1	S510	R511H	511	Missense	proximal	1	no	9.683	11.080	EPSD	COSMIC	10.919	Gain
Other_PLK_PLK1_PLK1_ST	P30622	CLIP1	P53350	PLK1	S510	R511C	511	Missense	proximal	1	no	9.683	11.082	EPSD	COSMIC	10.919	Gain
Other_PLK_PLK1_PLK1_ST	P30622	CLIP1	P53350	PLK1	S553	S553G	553	Missense	central	0	yes	13.493	0.000	EPSD	COSMIC	10.919	Loss
Other_PLK_PLK1_PLK1_ST	P30622	CLIP1	P53350	PLK1	S553	L549S	549	Missense	distal	-4	no	13.493	13.687	EPSD	COSMIC;CCLE	10.919	Up-regulation
Other_PLK_PLK1_PLK1_ST	P30622	CLIP1	P53350	PLK1	S709	R714W	714	Missense	distal	5	no	12.650	12.391	EPSD	COSMIC	10.919	Down-regulation
Other_PLK_PLK1_PLK1_ST	P30622	CLIP1	P53350	PLK1	S840	E841K	841	Missense	proximal	1	no	11.554	11.103	EPSD	COSMIC	10.919	Down-regulation
Other_PLK_PLK1_PLK1_ST	P30622	CLIP1	P53350	PLK1	S840	L835S	835	Missense	distal	-5	no	11.554	10.890	EPSD	COSMIC	10.919	Loss
Other_PLK_PLK1_PLK1_ST	P30622	CLIP1	P53350	PLK1	S937	M936R	936	Missense	proximal	-1	no	11.581	10.573	EPSD	COSMIC;GDSC	10.919	Loss
Other_PLK_PLK1_PLK1_ST	P30622	CLIP1	P53350	PLK1	S937	Q943K	943	Missense	distal	6	no	11.581	11.652	EPSD	COSMIC	10.919	Up-regulation
Other_PLK_PLK1_PLK1_ST	P30622	CLIP1	P53350	PLK1	S937	S941P	941	Missense	distal	4	no	11.581	11.259	EPSD	COSMIC	10.919	Down-regulation
Other_PLK_PLK1_PLK1_ST	P30622	CLIP1	P53350	PLK1	S937	M936V	936	Missense	proximal	-1	no	11.581	10.553	EPSD	COSMIC	10.919	Loss
Other_PLK_PLK1_PLK1_ST	P30622	CLIP1	P53350	PLK1	S973	E980Q	980	Missense	distal	7	no	12.479	12.532	EPSD	COSMIC	10.919	Up-regulation
Other_PLK_PLK1_PLK1_ST	P30622	CLIP1	P53350	PLK1	S973	E970K	970	Missense	distal	-3	no	12.479	13.020	EPSD	COSMIC	10.919	Up-regulation
Other_PLK_PLK1_PLK1_ST	P30622	CLIP1	P53350	PLK1	T983	M982V	982	Missense	proximal	-1	no	11.169	10.141	EPSD	COSMIC	10.919	Loss
Other_PLK_PLK1_PLK1_ST	P30622	CLIP1	P53350	PLK1	T983	E980Q	980	Missense	distal	-3	no	11.169	11.495	EPSD	COSMIC	10.919	Up-regulation
Other_PLK_PLK1_PLK1_ST	P30622	CLIP1	P53350	PLK1	T983	D981G	981	Missense	proximal	-2	no	11.169	7.847	EPSD	COSMIC	10.919	Loss
Other_PLK_PLK1_PLK1_ST	P30622	CLIP1	P53350	PLK1	S989	E992Q	992	Missense	distal	3	no	11.026	10.918	EPSD	COSMIC	10.919	Loss
Other_PLK_PLK1_PLK1_ST	P30622	CLIP1	P53350	PLK1	S989	M982V	982	Missense	distal	-7	no	11.026	11.159	EPSD	COSMIC	10.919	Up-regulation
Other_PLK_PLK1_PLK1_ST	P30622	CLIP1	P53350	PLK1	S989	K995E	995	Missense	distal	6	no	11.026	11.095	EPSD	COSMIC	10.919	Up-regulation
Other_PLK_PLK1_PLK1_ST	P30622	CLIP1	P53350	PLK1	S989	A993G	993	Missense	distal	4	no	11.026	11.139	EPSD	COSMIC;CCLE	10.919	Up-regulation
Other_PLK_PLK1_PLK1_ST	P30622	CLIP1	P53350	PLK1	S1066	R1062P	1062	Missense	distal	-4	no	11.272	11.717	EPSD	COSMIC	10.919	Up-regulation
Other_PLK_PLK1_PLK1_ST	P30622	CLIP1	P53350	PLK1	S1066	N1065K	1065	Missense	proximal	-1	no	11.272	10.838	EPSD	COSMIC	10.919	Loss
Other_PLK_PLK1_PLK1_ST	P30622	CLIP1	P53350	PLK1	T1112	L1119S	1119	Missense	distal	7	no	12.379	12.381	EPSD	COSMIC	10.919	Up-regulation
Other_PLK_PLK1_PLK1_ST	P30622	CLIP1	P53350	PLK1	T1112	T1105S	1105	Missense	distal	-7	no	12.379	12.388	EPSD	COSMIC	10.919	Up-regulation
Other_PLK_PLK1_PLK1_ST	P30622	CLIP1	P53350	PLK1	T1112	D1111N	1111	Missense	proximal	-1	no	12.379	11.446	EPSD	COSMIC	10.919	Down-regulation
Other_PLK_PLK1_PLK1_ST	P30622	CLIP1	P53350	PLK1	S1230	E1227A	1227	Missense	distal	-3	no	11.645	12.336	EPSD	COSMIC	10.919	Up-regulation
Other_PLK_PLK1_PLK1_ST	P30622	CLIP1	P53350	PLK1	S1230	A1229T	1229	Missense	proximal	-1	no	11.645	11.365	EPSD	COSMIC	10.919	Down-regulation
Other_PLK_PLK1_PLK1_ST	P30622	CLIP1	P53350	PLK1	S1302	Q1300E	1300	Missense	proximal	-2	no	10.001	12.661	EPSD	COSMIC	10.919	Gain
Other_PLK_PLK1_PLK1_ST	P30622	CLIP1	P53350	PLK1	S1364	S1364N	1364	Missense	central	0	yes	14.188	0.000	PhosphoSitePlus;EPSD	COSMIC	10.919	Loss
Other_PLK_PLK1_PLK1_ST	Q76N32	CEP68	P53350	PLK1	S126	S126F	126	Missense	central	0	yes	11.067	0.000	EPSD	COSMIC	10.919	Loss
Other_PLK_PLK1_PLK1_ST	Q76N32	CEP68	P53350	PLK1	S237	P236S	236	Missense	proximal	-1	no	10.130	11.304	EPSD	COSMIC	10.919	Gain
Other_PLK_PLK1_PLK1_ST	Q76N32	CEP68	P53350	PLK1	S260	R266H	266	Missense	distal	6	no	12.703	12.487	EPSD	COSMIC;CCLE	10.919	Down-regulation
Other_PLK_PLK1_PLK1_ST	Q76N32	CEP68	P53350	PLK1	S260	G257D	257	Missense	distal	-3	no	12.703	12.220	EPSD	COSMIC	10.919	Down-regulation
Other_PLK_PLK1_PLK1_ST	Q76N32	CEP68	P53350	PLK1	S260	L267I	267	Missense	distal	7	no	12.703	12.737	EPSD	COSMIC	10.919	Up-regulation
Other_PLK_PLK1_PLK1_ST	Q76N32	CEP68	P53350	PLK1	S260	D258G	258	Missense	proximal	-2	no	12.703	9.381	EPSD	COSMIC;GDSC;CCLE	10.919	Loss
Other_PLK_PLK1_PLK1_ST	Q76N32	CEP68	P53350	PLK1	S354	P355S	355	Missense	proximal	1	no	11.324	10.202	EPSD	COSMIC	10.919	Loss
Other_PLK_PLK1_PLK1_ST	Q76N32	CEP68	P53350	PLK1	S374	R381I	381	Missense	distal	7	no	13.003	13.019	EPSD	COSMIC	10.919	Up-regulation
Other_PLK_PLK1_PLK1_ST	Q76N32	CEP68	P53350	PLK1	S374	F367Y	367	Missense	distal	-7	no	13.003	12.848	EPSD	COSMIC	10.919	Down-regulation
Other_PLK_PLK1_PLK1_ST	Q76N32	CEP68	P53350	PLK1	S478	V476M	476	Missense	proximal	-2	no	13.046	12.550	EPSD	COSMIC	10.919	Down-regulation
Other_PLK_PLK1_PLK1_ST	Q76N32	CEP68	P53350	PLK1	S478	D480N	480	Missense	proximal	2	no	13.046	13.261	EPSD	COSMIC	10.919	Up-regulation
Other_PLK_PLK1_PLK1_ST	Q76N32	CEP68	P53350	PLK1	S577	G581R	581	Missense	distal	4	no	11.352	10.493	EPSD	COSMIC	10.919	Loss
Other_PLK_PLK1_PLK1_ST	Q76N32	CEP68	P53350	PLK1	S577	S573R	573	Missense	distal	-4	no	11.352	10.786	EPSD	COSMIC	10.919	Loss
Other_PLK_PLK1_PLK1_ST	Q76N32	CEP68	P53350	PLK1	S577	Q578L	578	Missense	proximal	1	no	11.352	12.505	EPSD	COSMIC	10.919	Up-regulation
Other_PLK_PLK1_PLK1_ST	P42898	MTHFR	P53350	PLK1	S18	P13L	13	Missense	distal	-5	no	11.711	12.112	EPSD	COSMIC	10.919	Up-regulation
Other_PLK_PLK1_PLK1_ST	P42898	MTHFR	P53350	PLK1	S18	P13H	13	Missense	distal	-5	no	11.711	11.329	EPSD	COSMIC	10.919	Down-regulation
Other_PLK_PLK1_PLK1_ST	P42898	MTHFR	P53350	PLK1	S18	S23R	23	Missense	distal	5	no	11.711	12.055	EPSD	COSMIC;CCLE	10.919	Up-regulation
Other_PLK_PLK1_PLK1_ST	P42898	MTHFR	P53350	PLK1	S21	S26T	26	Missense	distal	5	no	11.166	10.561	EPSD	COSMIC	10.919	Loss
Other_PLK_PLK1_PLK1_ST	P42898	MTHFR	P53350	PLK1	S21	S23R	23	Missense	proximal	2	no	11.166	10.438	EPSD	COSMIC;CCLE	10.919	Loss
Other_PLK_PLK1_PLK1_ST	P42898	MTHFR	P53350	PLK1	S26	S23R	23	Missense	distal	-3	no	12.009	12.841	EPSD	COSMIC;CCLE	10.919	Up-regulation
Other_PLK_PLK1_PLK1_ST	P42898	MTHFR	P53350	PLK1	S465	L460V	460	Missense	distal	-5	no	13.975	13.522	EPSD	COSMIC	10.919	Down-regulation
Other_PLK_PLK1_PLK1_ST	Q15435	PPP1R7	P53350	PLK1	S24	E17D	17	Missense	distal	-7	no	12.419	12.130	EPSD;PhosphoSitePlus	COSMIC	10.919	Down-regulation
Other_PLK_PLK1_PLK1_ST	Q15435	PPP1R7	P53350	PLK1	S24	D19H	19	Missense	distal	-5	no	12.419	12.056	EPSD;PhosphoSitePlus	COSMIC	10.919	Down-regulation
Other_PLK_PLK1_PLK1_ST	Q15435	PPP1R7	P53350	PLK1	S44	D42H	42	Missense	proximal	-2	no	12.279	9.092	PhosphoSitePlus;EPSD	COSMIC	10.919	Loss
Other_PLK_PLK1_PLK1_ST	Q15435	PPP1R7	P53350	PLK1	S47	D42H	42	Missense	distal	-5	no	13.541	13.178	EPSD;PhosphoSitePlus	COSMIC	10.919	Down-regulation
Other_PLK_PLK1_PLK1_ST	Q15468	STIL	P53350	PLK1	S147	L153P	153	Missense	distal	6	no	12.150	12.255	EPSD	COSMIC	10.919	Up-regulation
Other_PLK_PLK1_PLK1_ST	Q15468	STIL	P53350	PLK1	S147	H141Y	141	Missense	distal	-6	no	12.150	11.285	EPSD	COSMIC	10.919	Down-regulation
Other_PLK_PLK1_PLK1_ST	Q15468	STIL	P53350	PLK1	T237	G234E	234	Missense	distal	-3	no	13.348	12.406	EPSD	COSMIC	10.919	Down-regulation
Other_PLK_PLK1_PLK1_ST	Q15468	STIL	P53350	PLK1	S403	P406S	406	Missense	distal	3	no	11.467	11.445	EPSD	COSMIC	10.919	Down-regulation
Other_PLK_PLK1_PLK1_ST	Q15468	STIL	P53350	PLK1	S952	N950D	950	Missense	proximal	-2	no	9.744	10.987	EPSD	COSMIC	10.919	Gain
Other_PLK_PLK1_PLK1_ST	Q15468	STIL	P53350	PLK1	S1116	M1123I	1123	Missense	distal	7	no	14.476	14.440	EPSD;PhosphoSitePlus	COSMIC	10.919	Down-regulation
Other_PLK_PLK1_PLK1_ST	Q15468	STIL	P53350	PLK1	S1116	T1119I	1119	Missense	distal	3	no	14.476	14.643	EPSD;PhosphoSitePlus	COSMIC	10.919	Up-regulation
Other_PLK_PLK1_PLK1_ST	Q15468	STIL	P53350	PLK1	S1116	K1121N	1121	Missense	distal	5	no	14.476	14.153	EPSD;PhosphoSitePlus	COSMIC	10.919	Down-regulation
Other_PLK_PLK1_PLK1_ST	Q15468	STIL	P53350	PLK1	S1135	E1140K	1140	Missense	distal	5	no	12.034	12.045	EPSD	COSMIC	10.919	Up-regulation
Other_PLK_PLK1_PLK1_ST	Q15468	STIL	P53350	PLK1	S1135	S1135F	1135	Missense	central	0	yes	12.034	0.000	EPSD	COSMIC	10.919	Loss
Other_PLK_PLK1_PLK1_ST	Q15468	STIL	P53350	PLK1	S1135	L1128I	1128	Missense	distal	-7	no	12.034	11.876	EPSD	COSMIC	10.919	Down-regulation
Other_PLK_PLK1_PLK1_ST	Q15468	STIL	P53350	PLK1	S1135	E1138Q	1138	Missense	distal	3	no	12.034	11.926	EPSD	COSMIC	10.919	Down-regulation
Other_PLK_PLK1_PLK1_ST	Q15468	STIL	P53350	PLK1	S1135	E1139K	1139	Missense	distal	4	no	12.034	11.660	EPSD	COSMIC	10.919	Down-regulation
Other_PLK_PLK1_PLK1_ST	Q15468	STIL	P53350	PLK1	S1135	S1131N	1131	Missense	distal	-4	no	12.034	11.899	EPSD	COSMIC	10.919	Down-regulation
Other_PLK_PLK1_PLK1_ST	Q15468	STIL	P53350	PLK1	S1270	S1270L	1270	Missense	central	0	yes	11.449	0.000	EPSD	COSMIC	10.919	Loss
Other_PLK_PLK1_PLK1_ST	Q15468	STIL	P53350	PLK1	S1270	N1266D	1266	Missense	distal	-4	no	11.449	11.390	EPSD	COSMIC	10.919	Down-regulation
Other_PLK_PLK1_PLK1_ST	Q15468	STIL	P53350	PLK1	T1273	S1270L	1270	Missense	distal	-3	no	10.491	11.265	EPSD	COSMIC	10.919	Gain
Other_PLK_PLK1_PLK1_ST	Q9UJX5	ANAPC4	P53350	PLK1	S285	R286C	286	Missense	proximal	1	no	11.078	12.477	EPSD	COSMIC	10.919	Up-regulation
Other_PLK_PLK1_PLK1_ST	Q9UJX5	ANAPC4	P53350	PLK1	S285	R286S	286	Missense	proximal	1	no	11.078	12.242	EPSD	COSMIC	10.919	Up-regulation
Other_PLK_PLK1_PLK1_ST	Q9UJX5	ANAPC4	P53350	PLK1	S285	L280R	280	Missense	distal	-5	no	11.078	11.098	EPSD	COSMIC	10.919	Up-regulation
Other_PLK_PLK1_PLK1_ST	Q9UJX5	ANAPC4	P53350	PLK1	T446	D444V	444	Missense	proximal	-2	no	14.000	11.387	EPSD	COSMIC	10.919	Down-regulation
Other_PLK_PLK1_PLK1_ST	Q9UJX5	ANAPC4	P53350	PLK1	T446	M440V	440	Missense	distal	-6	no	14.000	13.843	EPSD	COSMIC	10.919	Down-regulation
Other_PLK_PLK1_PLK1_ST	Q9UJX5	ANAPC4	P53350	PLK1	T446	K443T	443	Missense	distal	-3	no	14.000	14.005	EPSD	COSMIC	10.919	Up-regulation
Other_PLK_PLK1_PLK1_ST	Q9UJX5	ANAPC4	P53350	PLK1	S757	A764V	764	Missense	distal	7	no	14.524	14.547	EPSD	COSMIC	10.919	Up-regulation
Other_PLK_PLK1_PLK1_ST	Q9UJX5	ANAPC4	P53350	PLK1	S757	D759V	759	Missense	proximal	2	no	14.524	14.729	EPSD	COSMIC	10.919	Up-regulation
Other_PLK_PLK1_PLK1_ST	Q9UJX5	ANAPC4	P53350	PLK1	S758	D759V	759	Missense	proximal	1	no	10.704	11.337	EPSD	COSMIC	10.919	Gain
Other_PLK_PLK1_PLK1_ST	Q92574	TSC1	P53350	PLK1	S115	L120F	120	Missense	distal	5	no	11.424	11.864	EPSD	COSMIC	10.919	Up-regulation
Other_PLK_PLK1_PLK1_ST	Q92574	TSC1	P53350	PLK1	S115	S108F	108	Missense	distal	-7	no	11.424	10.967	EPSD	COSMIC	10.919	Down-regulation
Other_PLK_PLK1_PLK1_ST	Q92574	TSC1	P53350	PLK1	S115	S108P	108	Missense	distal	-7	no	11.424	11.213	EPSD	COSMIC	10.919	Down-regulation
Other_PLK_PLK1_PLK1_ST	Q92574	TSC1	P53350	PLK1	S115	M122I	122	Missense	distal	7	no	11.424	11.388	EPSD	COSMIC	10.919	Down-regulation
Other_PLK_PLK1_PLK1_ST	Q92574	TSC1	P53350	PLK1	T267	K261E	261	Missense	distal	-6	no	10.670	11.243	EPSD	COSMIC	10.919	Gain
Other_PLK_PLK1_PLK1_ST	Q92574	TSC1	P53350	PLK1	T267	P266S	266	Missense	proximal	-1	no	10.670	11.844	EPSD	COSMIC	10.919	Gain
Other_PLK_PLK1_PLK1_ST	Q92574	TSC1	P53350	PLK1	S270	D265A	265	Missense	distal	-5	no	12.078	12.118	EPSD	COSMIC	10.919	Up-regulation
Other_PLK_PLK1_PLK1_ST	Q92574	TSC1	P53350	PLK1	S270	P266S	266	Missense	distal	-4	no	12.078	12.200	EPSD	COSMIC	10.919	Up-regulation
Other_PLK_PLK1_PLK1_ST	Q92574	TSC1	P53350	PLK1	S270	Y275F	275	Missense	distal	5	no	12.078	12.329	EPSD	COSMIC	10.919	Up-regulation
Other_PLK_PLK1_PLK1_ST	Q92574	TSC1	P53350	PLK1	S270	S276F	276	Missense	distal	6	no	12.078	11.502	EPSD	COSMIC	10.919	Down-regulation
Other_PLK_PLK1_PLK1_ST	Q92574	TSC1	P53350	PLK1	S270	S270P	270	Missense	central	0	yes	12.078	0.000	EPSD	COSMIC	10.919	Loss
Other_PLK_PLK1_PLK1_ST	Q92574	TSC1	P53350	PLK1	S289	H287D	287	Missense	proximal	-2	no	8.129	11.316	EPSD	COSMIC	10.919	Gain
Other_PLK_PLK1_PLK1_ST	Q92574	TSC1	P53350	PLK1	T293	R288C	288	Missense	distal	-5	no	11.905	11.240	EPSD	COSMIC	10.919	Down-regulation
Other_PLK_PLK1_PLK1_ST	Q92574	TSC1	P53350	PLK1	T293	H287D	287	Missense	distal	-6	no	11.905	11.810	EPSD	COSMIC	10.919	Down-regulation
Other_PLK_PLK1_PLK1_ST	Q92574	TSC1	P53350	PLK1	S331	S332F	332	Missense	proximal	1	no	11.231	14.279	EPSD	COSMIC	10.919	Up-regulation
Other_PLK_PLK1_PLK1_ST	Q92574	TSC1	P53350	PLK1	S374	P372S	372	Missense	proximal	-2	no	11.007	11.591	EPSD	COSMIC	10.919	Up-regulation
Other_PLK_PLK1_PLK1_ST	Q92574	TSC1	P53350	PLK1	S374	P372L	372	Missense	proximal	-2	no	11.007	10.643	EPSD	COSMIC	10.919	Loss
Other_PLK_PLK1_PLK1_ST	Q92574	TSC1	P53350	PLK1	S374	L369V	369	Missense	distal	-5	no	11.007	10.554	EPSD	COSMIC	10.919	Loss
Other_PLK_PLK1_PLK1_ST	Q92574	TSC1	P53350	PLK1	S374	V376A	376	Missense	proximal	2	no	11.007	10.563	EPSD	COSMIC	10.919	Loss
Other_PLK_PLK1_PLK1_ST	Q92574	TSC1	P53350	PLK1	S374	Y373C	373	Missense	proximal	-1	no	11.007	8.811	EPSD	COSMIC;GDSC;CCLE	10.919	Loss
Other_PLK_PLK1_PLK1_ST	Q92574	TSC1	P53350	PLK1	S374	H371Q	371	Missense	distal	-3	no	11.007	11.004	EPSD	COSMIC	10.919	Down-regulation
Other_PLK_PLK1_PLK1_ST	Q92574	TSC1	P53350	PLK1	S472	K477E	477	Missense	distal	5	no	15.054	15.043	EPSD	COSMIC	10.919	Down-regulation
Other_PLK_PLK1_PLK1_ST	Q92574	TSC1	P53350	PLK1	S472	S468F	468	Missense	distal	-4	no	15.054	14.735	EPSD	COSMIC	10.919	Down-regulation
Other_PLK_PLK1_PLK1_ST	Q92574	TSC1	P53350	PLK1	S472	S472N	472	Missense	central	0	yes	15.054	0.000	EPSD	COSMIC;GDSC;CCLE	10.919	Loss
Other_PLK_PLK1_PLK1_ST	Q92574	TSC1	P53350	PLK1	S472	E478Q	478	Missense	distal	6	no	15.054	14.913	EPSD	COSMIC	10.919	Down-regulation
Other_PLK_PLK1_PLK1_ST	Q92574	TSC1	P53350	PLK1	S487	I482V	482	Missense	distal	-5	no	11.981	11.824	EPSD	COSMIC	10.919	Down-regulation
Other_PLK_PLK1_PLK1_ST	Q92574	TSC1	P53350	PLK1	S487	I482M	482	Missense	distal	-5	no	11.981	11.677	EPSD	COSMIC	10.919	Down-regulation
Other_PLK_PLK1_PLK1_ST	Q92574	TSC1	P53350	PLK1	S487	E485D	485	Missense	proximal	-2	no	11.981	12.375	EPSD	COSMIC	10.919	Up-regulation
Other_PLK_PLK1_PLK1_ST	Q92574	TSC1	P53350	PLK1	S487	E488V	488	Missense	proximal	1	no	11.981	12.858	EPSD	COSMIC	10.919	Up-regulation
Other_PLK_PLK1_PLK1_ST	Q92574	TSC1	P53350	PLK1	S487	S487C	487	Missense	central	0	yes	11.981	0.000	EPSD	COSMIC	10.919	Loss
Other_PLK_PLK1_PLK1_ST	Q92574	TSC1	P53350	PLK1	T490	E485D	485	Missense	distal	-5	no	11.290	11.632	EPSD	COSMIC	10.919	Up-regulation
Other_PLK_PLK1_PLK1_ST	Q92574	TSC1	P53350	PLK1	T490	E488V	488	Missense	proximal	-2	no	11.290	9.072	EPSD	COSMIC	10.919	Loss
Other_PLK_PLK1_PLK1_ST	Q92574	TSC1	P53350	PLK1	T490	S487C	487	Missense	distal	-3	no	11.290	11.326	EPSD	COSMIC	10.919	Up-regulation
Other_PLK_PLK1_PLK1_ST	Q92574	TSC1	P53350	PLK1	S511	P506T	506	Missense	distal	-5	no	11.428	11.381	EPSD	COSMIC	10.919	Down-regulation
Other_PLK_PLK1_PLK1_ST	Q92574	TSC1	P53350	PLK1	S511	P506L	506	Missense	distal	-5	no	11.428	11.830	EPSD	COSMIC	10.919	Up-regulation
Other_PLK_PLK1_PLK1_ST	Q92574	TSC1	P53350	PLK1	S511	P513L	513	Missense	proximal	2	no	11.428	12.976	EPSD	COSMIC	10.919	Up-regulation
Other_PLK_PLK1_PLK1_ST	Q92574	TSC1	P53350	PLK1	S511	S505P	505	Missense	distal	-6	no	11.428	10.805	EPSD	COSMIC	10.919	Loss
Other_PLK_PLK1_PLK1_ST	Q92574	TSC1	P53350	PLK1	S511	R517W	517	Missense	distal	6	no	11.428	11.449	EPSD	COSMIC	10.919	Up-regulation
Other_PLK_PLK1_PLK1_ST	Q92574	TSC1	P53350	PLK1	S539	K542E	542	Missense	distal	3	no	10.753	10.959	EPSD	COSMIC	10.919	Gain
Other_PLK_PLK1_PLK1_ST	Q92574	TSC1	P53350	PLK1	S565	C572Y	572	Missense	distal	7	no	14.090	14.077	EPSD	COSMIC;GDSC;CCLE	10.919	Down-regulation
Other_PLK_PLK1_PLK1_ST	Q92574	TSC1	P53350	PLK1	S565	G560S	560	Missense	distal	-5	no	14.090	13.691	EPSD	COSMIC	10.919	Down-regulation
Other_PLK_PLK1_PLK1_ST	Q92574	TSC1	P53350	PLK1	S565	P566H	566	Missense	proximal	1	no	14.090	13.201	EPSD	COSMIC	10.919	Down-regulation
Other_PLK_PLK1_PLK1_ST	Q92574	TSC1	P53350	PLK1	S565	A567V	567	Missense	proximal	2	no	14.090	14.533	EPSD	COSMIC	10.919	Up-regulation
Other_PLK_PLK1_PLK1_ST	Q92574	TSC1	P53350	PLK1	S565	E564K	564	Missense	proximal	-1	no	14.090	13.519	EPSD	COSMIC	10.919	Down-regulation
Other_PLK_PLK1_PLK1_ST	Q92574	TSC1	P53350	PLK1	S575	Q573E	573	Missense	proximal	-2	no	9.466	12.125	EPSD	COSMIC	10.919	Gain
Other_PLK_PLK1_PLK1_ST	Q92574	TSC1	P53350	PLK1	S579	L576R	576	Missense	distal	-3	no	13.965	14.023	EPSD;PhosphoSitePlus	COSMIC	10.919	Up-regulation
Other_PLK_PLK1_PLK1_ST	Q92574	TSC1	P53350	PLK1	S579	C572Y	572	Missense	distal	-7	no	13.965	13.971	EPSD;PhosphoSitePlus	COSMIC;GDSC;CCLE	10.919	Up-regulation
Other_PLK_PLK1_PLK1_ST	Q92574	TSC1	P53350	PLK1	S579	P585A	585	Missense	distal	6	no	13.965	14.104	EPSD;PhosphoSitePlus	COSMIC	10.919	Up-regulation
Other_PLK_PLK1_PLK1_ST	Q92574	TSC1	P53350	PLK1	S579	E577K	577	Missense	proximal	-2	no	13.965	11.088	EPSD;PhosphoSitePlus	COSMIC	10.919	Down-regulation
Other_PLK_PLK1_PLK1_ST	Q92574	TSC1	P53350	PLK1	S579	Q573E	573	Missense	distal	-6	no	13.965	14.084	EPSD;PhosphoSitePlus	COSMIC	10.919	Up-regulation
Other_PLK_PLK1_PLK1_ST	Q92574	TSC1	P53350	PLK1	S579	P583S	583	Missense	distal	4	no	13.965	14.287	EPSD;PhosphoSitePlus	COSMIC	10.919	Up-regulation
Other_PLK_PLK1_PLK1_ST	Q92574	TSC1	P53350	PLK1	S579	E577D	577	Missense	proximal	-2	no	13.965	14.359	EPSD;PhosphoSitePlus	COSMIC	10.919	Up-regulation
Other_PLK_PLK1_PLK1_ST	Q92574	TSC1	P53350	PLK1	S1025	G1031S	1031	Missense	distal	6	no	10.841	11.045	EPSD	COSMIC	10.919	Gain
Other_PLK_PLK1_PLK1_ST	Q92574	TSC1	P53350	PLK1	S1025	K1019M	1019	Missense	distal	-6	no	10.841	11.178	EPSD	COSMIC	10.919	Gain
Other_PLK_PLK1_PLK1_ST	Q92574	TSC1	P53350	PLK1	S1030	G1034S	1034	Missense	distal	4	no	13.134	13.219	EPSD	COSMIC	10.919	Up-regulation
Other_PLK_PLK1_PLK1_ST	Q92574	TSC1	P53350	PLK1	S1030	G1036S	1036	Missense	distal	6	no	13.134	13.338	EPSD	COSMIC	10.919	Up-regulation
Other_PLK_PLK1_PLK1_ST	Q92574	TSC1	P53350	PLK1	S1030	G1034C	1034	Missense	distal	4	no	13.134	12.692	EPSD	COSMIC;GDSC;CCLE	10.919	Down-regulation
Other_PLK_PLK1_PLK1_ST	Q92574	TSC1	P53350	PLK1	S1030	G1037S	1037	Missense	distal	7	no	13.134	13.135	EPSD	COSMIC	10.919	Up-regulation
Other_PLK_PLK1_PLK1_ST	Q92574	TSC1	P53350	PLK1	S1030	S1029N	1029	Missense	proximal	-1	no	13.134	12.993	EPSD	COSMIC	10.919	Down-regulation
Other_PLK_PLK1_PLK1_ST	Q92574	TSC1	P53350	PLK1	S1030	G1028C	1028	Missense	proximal	-2	no	13.134	11.404	EPSD	COSMIC	10.919	Down-regulation
Other_PLK_PLK1_PLK1_ST	Q92574	TSC1	P53350	PLK1	S1030	G1031S	1031	Missense	proximal	1	no	13.134	12.197	EPSD	COSMIC	10.919	Down-regulation
Other_PLK_PLK1_PLK1_ST	Q92574	TSC1	P53350	PLK1	S1030	G1035S	1035	Missense	distal	5	no	13.134	12.951	EPSD	COSMIC	10.919	Down-regulation
Other_PLK_PLK1_PLK1_ST	Q92574	TSC1	P53350	PLK1	S1030	S1032R	1032	Missense	proximal	2	no	13.134	12.406	EPSD	COSMIC	10.919	Down-regulation
Other_PLK_PLK1_PLK1_ST	Q92574	TSC1	P53350	PLK1	S1030	S1024N	1024	Missense	distal	-6	no	13.134	12.937	EPSD	COSMIC	10.919	Down-regulation
Other_PLK_PLK1_PLK1_ST	Q92574	TSC1	P53350	PLK1	S1040	G1036S	1036	Missense	distal	-4	no	10.306	10.959	EPSD	COSMIC	10.919	Gain
Other_PLK_PLK1_PLK1_ST	Q92574	TSC1	P53350	PLK1	S1040	S1038N	1038	Missense	proximal	-2	no	10.306	11.715	EPSD	COSMIC	10.919	Gain
Other_PLK_PLK1_PLK1_ST	Q92574	TSC1	P53350	PLK1	S1046	T1047I	1047	Missense	proximal	1	no	10.316	11.483	EPSD	COSMIC;CCLE	10.919	Gain
Other_PLK_PLK1_PLK1_ST	Q92574	TSC1	P53350	PLK1	S1071	E1064K	1064	Missense	distal	-7	no	11.015	10.711	EPSD	COSMIC	10.919	Loss
Other_PLK_PLK1_PLK1_ST	Q92574	TSC1	P53350	PLK1	S1071	E1069D	1069	Missense	proximal	-2	no	11.015	11.408	EPSD	COSMIC	10.919	Up-regulation
Other_PLK_PLK1_PLK1_ST	Q92574	TSC1	P53350	PLK1	S1071	T1065M	1065	Missense	distal	-6	no	11.015	10.999	EPSD	COSMIC	10.919	Down-regulation
Other_PLK_PLK1_PLK1_ST	Q92574	TSC1	P53350	PLK1	S1071	A1070T	1070	Missense	proximal	-1	no	11.015	10.734	EPSD	COSMIC	10.919	Loss
Other_PLK_PLK1_PLK1_ST	Q92574	TSC1	P53350	PLK1	S1071	A1072T	1072	Missense	proximal	1	no	11.015	11.477	EPSD	COSMIC	10.919	Up-regulation
Other_PLK_PLK1_PLK1_ST	Q92574	TSC1	P53350	PLK1	S1086	K1091T	1091	Missense	distal	5	no	11.172	10.848	EPSD	COSMIC	10.919	Loss
Other_PLK_PLK1_PLK1_ST	Q92574	TSC1	P53350	PLK1	S1086	K1085T	1085	Missense	proximal	-1	no	11.172	11.000	EPSD	COSMIC	10.919	Down-regulation
Other_PLK_PLK1_PLK1_ST	Q92574	TSC1	P53350	PLK1	S1086	L1088V	1088	Missense	proximal	2	no	11.172	11.304	EPSD	COSMIC	10.919	Up-regulation
Other_PLK_PLK1_PLK1_ST	Q92574	TSC1	P53350	PLK1	S1100	E1106K	1106	Missense	distal	6	no	12.001	11.932	EPSD	COSMIC	10.919	Down-regulation
Other_PLK_PLK1_PLK1_ST	Q92574	TSC1	P53350	PLK1	S1100	K1099R	1099	Missense	proximal	-1	no	12.001	11.639	EPSD	COSMIC	10.919	Down-regulation
Other_PLK_PLK1_PLK1_ST	Q92574	TSC1	P53350	PLK1	S1100	S1100N	1100	Missense	central	0	yes	12.001	0.000	EPSD	COSMIC	10.919	Loss
Other_PLK_PLK1_PLK1_ST	Q92574	TSC1	P53350	PLK1	S1112	E1106K	1106	Missense	distal	-6	no	12.074	11.500	EPSD	COSMIC	10.919	Down-regulation
Other_PLK_PLK1_PLK1_ST	Q92574	TSC1	P53350	PLK1	S1112	E1115K	1115	Missense	distal	3	no	12.074	11.867	EPSD	COSMIC	10.919	Down-regulation
Other_PLK_PLK1_PLK1_ST	Q92574	TSC1	P53350	PLK1	S1112	G1108S	1108	Missense	distal	-4	no	12.074	12.727	EPSD	COSMIC	10.919	Up-regulation
Other_PLK_PLK1_PLK1_ST	Q92574	TSC1	P53350	PLK1	S1112	E1115D	1115	Missense	distal	3	no	12.074	12.139	EPSD	COSMIC	10.919	Up-regulation
Other_PLK_PLK1_PLK1_ST	Q92574	TSC1	P53350	PLK1	S1116	E1120D	1120	Missense	distal	4	no	11.499	11.514	EPSD	COSMIC	10.919	Up-regulation
Other_PLK_PLK1_PLK1_ST	Q92574	TSC1	P53350	PLK1	S1116	E1115K	1115	Missense	proximal	-1	no	11.499	10.928	EPSD	COSMIC	10.919	Down-regulation
Other_PLK_PLK1_PLK1_ST	Q92574	TSC1	P53350	PLK1	S1116	E1115D	1115	Missense	proximal	-1	no	11.499	12.296	EPSD	COSMIC	10.919	Up-regulation
Other_PLK_PLK1_PLK1_ST	O60566	BUB1B	P53350	PLK1	S270	S270C	270	Missense	central	0	yes	11.658	0.000	EPSD	COSMIC	10.919	Loss
Other_PLK_PLK1_PLK1_ST	O60566	BUB1B	P53350	PLK1	S270	N269Y	269	Missense	proximal	-1	no	11.658	12.134	EPSD	COSMIC	10.919	Up-regulation
Other_PLK_PLK1_PLK1_ST	O60566	BUB1B	P53350	PLK1	T471	E476K	476	Missense	distal	5	no	12.126	12.137	EPSD	COSMIC	10.919	Up-regulation
Other_PLK_PLK1_PLK1_ST	O60566	BUB1B	P53350	PLK1	S543	P545L	545	Missense	proximal	2	no	9.787	11.335	EPSD	COSMIC	10.919	Gain
Other_PLK_PLK1_PLK1_ST	O60566	BUB1B	P53350	PLK1	S574	V577I	577	Missense	distal	3	no	11.781	11.659	EPSD	COSMIC	10.919	Down-regulation
Other_PLK_PLK1_PLK1_ST	O60566	BUB1B	P53350	PLK1	T582	V577I	577	Missense	distal	-5	no	11.089	11.247	EPSD	COSMIC	10.919	Up-regulation
Other_PLK_PLK1_PLK1_ST	O60566	BUB1B	P53350	PLK1	T608	P603S	603	Missense	distal	-5	no	11.845	11.582	EPSD	COSMIC	10.919	Down-regulation
Other_PLK_PLK1_PLK1_ST	O60566	BUB1B	P53350	PLK1	T608	D610H	610	Missense	proximal	2	no	11.845	11.821	EPSD	COSMIC	10.919	Down-regulation
Other_PLK_PLK1_PLK1_ST	O60566	BUB1B	P53350	PLK1	T608	A612T	612	Missense	distal	4	no	11.845	11.851	EPSD	COSMIC	10.919	Up-regulation
Other_PLK_PLK1_PLK1_ST	O60566	BUB1B	P53350	PLK1	S676	S670R	670	Missense	distal	-6	no	12.761	12.314	EPSD;PhosphoSitePlus	COSMIC	10.919	Down-regulation
Other_PLK_PLK1_PLK1_ST	O60566	BUB1B	P53350	PLK1	S676	I672S	672	Missense	distal	-4	no	12.761	12.727	EPSD;PhosphoSitePlus	COSMIC;GDSC;CCLE	10.919	Down-regulation
Other_PLK_PLK1_PLK1_ST	O60566	BUB1B	P53350	PLK1	S676	S670I	670	Missense	distal	-6	no	12.761	12.830	EPSD;PhosphoSitePlus	COSMIC;GDSC	10.919	Up-regulation
Other_PLK_PLK1_PLK1_ST	O60566	BUB1B	P53350	PLK1	T680	F685L	685	Missense	distal	5	no	13.297	12.856	EPSD;PhosphoSitePlus	COSMIC	10.919	Down-regulation
Other_PLK_PLK1_PLK1_ST	O60566	BUB1B	P53350	PLK1	T680	F685C	685	Missense	distal	5	no	13.297	13.332	EPSD;PhosphoSitePlus	COSMIC	10.919	Up-regulation
Other_PLK_PLK1_PLK1_ST	O60566	BUB1B	P53350	PLK1	S683	F685L	685	Missense	proximal	2	no	11.145	11.768	EPSD	COSMIC	10.919	Up-regulation
Other_PLK_PLK1_PLK1_ST	O60566	BUB1B	P53350	PLK1	S683	F685C	685	Missense	proximal	2	no	11.145	10.724	EPSD	COSMIC	10.919	Loss
Other_PLK_PLK1_PLK1_ST	O60566	BUB1B	P53350	PLK1	S696	S697F	697	Missense	proximal	1	no	9.647	12.695	EPSD	COSMIC	10.919	Gain
Other_PLK_PLK1_PLK1_ST	O60566	BUB1B	P53350	PLK1	S884	H880R	880	Missense	distal	-4	no	13.111	12.810	EPSD	COSMIC	10.919	Down-regulation
Other_PLK_PLK1_PLK1_ST	O60566	BUB1B	P53350	PLK1	S884	I878T	878	Missense	distal	-6	no	13.111	12.939	EPSD	COSMIC	10.919	Down-regulation
Other_PLK_PLK1_PLK1_ST	O60566	BUB1B	P53350	PLK1	S884	C887F	887	Missense	distal	3	no	13.111	13.235	EPSD	COSMIC	10.919	Up-regulation
Other_PLK_PLK1_PLK1_ST	O60566	BUB1B	P53350	PLK1	S884	L890F	890	Missense	distal	6	no	13.111	12.495	EPSD	COSMIC	10.919	Down-regulation
Other_PLK_PLK1_PLK1_ST	O60566	BUB1B	P53350	PLK1	T1008	E1006Q	1006	Missense	proximal	-2	no	11.310	8.651	PhosphoSitePlus;EPSD	COSMIC	10.919	Loss
Other_PLK_PLK1_PLK1_ST	Q14790	CASP8	P53350	PLK1	S16	S21F	21	Missense	distal	5	no	12.066	12.160	EPSD	COSMIC	10.919	Up-regulation
Other_PLK_PLK1_PLK1_ST	Q14790	CASP8	P53350	PLK1	S16	K23E	23	Missense	distal	7	no	12.066	11.993	EPSD	COSMIC	10.919	Down-regulation
Other_PLK_PLK1_PLK1_ST	Q14790	CASP8	P53350	PLK1	S16	D9N	9	Missense	distal	-7	no	12.066	12.206	EPSD	COSMIC	10.919	Up-regulation
Other_PLK_PLK1_PLK1_ST	Q14790	CASP8	P53350	PLK1	S16	D18H	18	Missense	proximal	2	no	12.066	12.042	EPSD	COSMIC	10.919	Down-regulation
Other_PLK_PLK1_PLK1_ST	Q14790	CASP8	P53350	PLK1	S26	S21F	21	Missense	distal	-5	no	11.439	11.178	EPSD	COSMIC	10.919	Down-regulation
Other_PLK_PLK1_PLK1_ST	Q14790	CASP8	P53350	PLK1	S26	K23E	23	Missense	distal	-3	no	11.439	10.899	EPSD	COSMIC	10.919	Loss
Other_PLK_PLK1_PLK1_ST	Q14790	CASP8	P53350	PLK1	S26	D28Y	28	Missense	proximal	2	no	11.439	11.073	EPSD	COSMIC	10.919	Down-regulation
Other_PLK_PLK1_PLK1_ST	Q14790	CASP8	P53350	PLK1	S26	Y29H	29	Missense	distal	3	no	11.439	11.627	EPSD	COSMIC	10.919	Up-regulation
Other_PLK_PLK1_PLK1_ST	Q14790	CASP8	P53350	PLK1	S60	K63T	63	Missense	distal	3	no	11.832	11.721	EPSD	COSMIC	10.919	Down-regulation
Other_PLK_PLK1_PLK1_ST	Q14790	CASP8	P53350	PLK1	S60	S60F	60	Missense	central	0	yes	11.832	0.000	EPSD	COSMIC	10.919	Loss
Other_PLK_PLK1_PLK1_ST	Q14790	CASP8	P53350	PLK1	S60	L54S	54	Missense	distal	-6	no	11.832	12.166	EPSD	COSMIC	10.919	Up-regulation
Other_PLK_PLK1_PLK1_ST	Q14790	CASP8	P53350	PLK1	S60	L65R	65	Missense	distal	5	no	11.832	12.523	EPSD	COSMIC	10.919	Up-regulation
Other_PLK_PLK1_PLK1_ST	Q14790	CASP8	P53350	PLK1	S60	L66H	66	Missense	distal	6	no	11.832	11.270	EPSD	COSMIC	10.919	Down-regulation
Other_PLK_PLK1_PLK1_ST	Q14790	CASP8	P53350	PLK1	S113	V112M	112	Missense	proximal	-1	no	11.119	12.148	EPSD	COSMIC	10.919	Up-regulation
Other_PLK_PLK1_PLK1_ST	Q14790	CASP8	P53350	PLK1	S113	S109P	109	Missense	distal	-4	no	11.119	10.997	EPSD	COSMIC	10.919	Down-regulation
Other_PLK_PLK1_PLK1_ST	Q14790	CASP8	P53350	PLK1	S113	E116K	116	Missense	distal	3	no	11.119	10.913	EPSD	COSMIC	10.919	Loss
Other_PLK_PLK1_PLK1_ST	Q14790	CASP8	P53350	PLK1	S113	S119Y	119	Missense	distal	6	no	11.119	10.591	EPSD	COSMIC	10.919	Loss
Other_PLK_PLK1_PLK1_ST	Q14790	CASP8	P53350	PLK1	S113	E110K	110	Missense	distal	-3	no	11.119	11.659	EPSD	COSMIC	10.919	Up-regulation
Other_PLK_PLK1_PLK1_ST	Q14790	CASP8	P53350	PLK1	S113	I108T	108	Missense	distal	-5	no	11.119	10.966	EPSD	COSMIC	10.919	Down-regulation
Other_PLK_PLK1_PLK1_ST	Q14790	CASP8	P53350	PLK1	S113	E116V	116	Missense	distal	3	no	11.119	11.091	EPSD	COSMIC	10.919	Down-regulation
Other_PLK_PLK1_PLK1_ST	Q14790	CASP8	P53350	PLK1	S113	F120L	120	Missense	distal	7	no	11.119	11.048	EPSD	COSMIC	10.919	Down-regulation
Other_PLK_PLK1_PLK1_ST	Q14790	CASP8	P53350	PLK1	S113	S119F	119	Missense	distal	6	no	11.119	10.543	EPSD	COSMIC	10.919	Loss
Other_PLK_PLK1_PLK1_ST	Q14790	CASP8	P53350	PLK1	S113	S119P	119	Missense	distal	6	no	11.119	11.263	EPSD	COSMIC	10.919	Up-regulation
Other_PLK_PLK1_PLK1_ST	Q14790	CASP8	P53350	PLK1	S186	E184Q	184	Missense	proximal	-2	no	11.331	8.672	EPSD	COSMIC	10.919	Loss
Other_PLK_PLK1_PLK1_ST	Q14790	CASP8	P53350	PLK1	S186	S186N	186	Missense	central	0	yes	11.331	0.000	EPSD	COSMIC	10.919	Loss
Other_PLK_PLK1_PLK1_ST	Q14790	CASP8	P53350	PLK1	S186	E179D	179	Missense	distal	-7	no	11.331	11.042	EPSD	COSMIC	10.919	Down-regulation
Other_PLK_PLK1_PLK1_ST	Q14790	CASP8	P53350	PLK1	S186	S188A	188	Missense	proximal	2	no	11.331	11.091	EPSD	COSMIC	10.919	Down-regulation
Other_PLK_PLK1_PLK1_ST	Q14790	CASP8	P53350	PLK1	S186	E179Q	179	Missense	distal	-7	no	11.331	11.295	EPSD	COSMIC	10.919	Down-regulation
Other_PLK_PLK1_PLK1_ST	Q14790	CASP8	P53350	PLK1	S188	E184Q	184	Missense	distal	-4	no	11.047	10.779	EPSD	COSMIC	10.919	Loss
Other_PLK_PLK1_PLK1_ST	Q14790	CASP8	P53350	PLK1	S188	S186N	186	Missense	proximal	-2	no	11.047	12.457	EPSD	COSMIC	10.919	Up-regulation
Other_PLK_PLK1_PLK1_ST	Q14790	CASP8	P53350	PLK1	S188	S188A	188	Missense	central	0	yes	11.047	0.000	EPSD	COSMIC	10.919	Loss
Other_PLK_PLK1_PLK1_ST	Q14790	CASP8	P53350	PLK1	S192	S186N	186	Missense	distal	-6	no	11.047	10.850	EPSD	COSMIC	10.919	Loss
Other_PLK_PLK1_PLK1_ST	Q14790	CASP8	P53350	PLK1	S192	S188A	188	Missense	distal	-4	no	11.047	11.086	EPSD	COSMIC	10.919	Up-regulation
Other_PLK_PLK1_PLK1_ST	Q14790	CASP8	P53350	PLK1	S211	S211L	211	Missense	central	0	yes	13.740	0.000	EPSD	COSMIC	10.919	Loss
Other_PLK_PLK1_PLK1_ST	Q14790	CASP8	P53350	PLK1	S211	V205I	205	Missense	distal	-6	no	13.740	14.084	EPSD	COSMIC	10.919	Up-regulation
Other_PLK_PLK1_PLK1_ST	Q14790	CASP8	P53350	PLK1	S211	S209L	209	Missense	proximal	-2	no	13.740	12.792	EPSD	COSMIC	10.919	Down-regulation
Other_PLK_PLK1_PLK1_ST	Q14790	CASP8	P53350	PLK1	S211	T207I	207	Missense	distal	-4	no	13.740	14.136	EPSD	COSMIC	10.919	Up-regulation
Other_PLK_PLK1_PLK1_ST	Q14790	CASP8	P53350	PLK1	S211	S211C	211	Missense	central	0	yes	13.740	0.000	EPSD	COSMIC	10.919	Loss
Other_PLK_PLK1_PLK1_ST	Q14790	CASP8	P53350	PLK1	S211	D216G	216	Missense	distal	5	no	13.740	13.774	EPSD	COSMIC	10.919	Up-regulation
Other_PLK_PLK1_PLK1_ST	Q14790	CASP8	P53350	PLK1	S211	P212L	212	Missense	proximal	1	no	13.740	14.586	EPSD	COSMIC	10.919	Up-regulation
Other_PLK_PLK1_PLK1_ST	Q14790	CASP8	P53350	PLK1	S211	P212T	212	Missense	proximal	1	no	13.740	13.211	EPSD	COSMIC	10.919	Down-regulation
Other_PLK_PLK1_PLK1_ST	Q14790	CASP8	P53350	PLK1	S211	P212A	212	Missense	proximal	1	no	13.740	12.749	EPSD	COSMIC	10.919	Down-regulation
Other_PLK_PLK1_PLK1_ST	Q14790	CASP8	P53350	PLK1	S211	R213S	213	Missense	proximal	2	no	13.740	14.468	EPSD	COSMIC	10.919	Up-regulation
Other_PLK_PLK1_PLK1_ST	Q14790	CASP8	P53350	PLK1	S305	C309Y	309	Missense	distal	4	no	12.108	12.391	PhosphoSitePlus	COSMIC	10.919	Up-regulation
Other_PLK_PLK1_PLK1_ST	Q14790	CASP8	P53350	PLK1	S305	D303H	303	Missense	proximal	-2	no	12.108	8.921	PhosphoSitePlus	COSMIC	10.919	Loss
Other_PLK_PLK1_PLK1_ST	Q14790	CASP8	P53350	PLK1	S305	L301P	301	Missense	distal	-4	no	12.108	12.179	PhosphoSitePlus	COSMIC;CCLE	10.919	Up-regulation
Other_PLK_PLK1_PLK1_ST	Q14790	CASP8	P53350	PLK1	S305	H304D	304	Missense	proximal	-1	no	12.108	12.840	PhosphoSitePlus	COSMIC	10.919	Up-regulation
Other_PLK_PLK1_PLK1_ST	Q14790	CASP8	P53350	PLK1	S305	D303G	303	Missense	proximal	-2	no	12.108	8.786	PhosphoSitePlus	COSMIC	10.919	Loss
Other_PLK_PLK1_PLK1_ST	Q14790	CASP8	P53350	PLK1	S305	C312S	312	Missense	distal	7	no	12.108	12.039	PhosphoSitePlus	COSMIC	10.919	Down-regulation
Other_PLK_PLK1_PLK1_ST	Q14790	CASP8	P53350	PLK1	S305	N306S	306	Missense	proximal	1	no	12.108	11.368	PhosphoSitePlus	COSMIC	10.919	Down-regulation
Other_PLK_PLK1_PLK1_ST	Q14790	CASP8	P53350	PLK1	S305	D308Y	308	Missense	distal	3	no	12.108	11.682	PhosphoSitePlus	COSMIC	10.919	Down-regulation
Other_PLK_PLK1_PLK1_ST	Q14790	CASP8	P53350	PLK1	S305	D303V	303	Missense	proximal	-2	no	12.108	9.495	PhosphoSitePlus	COSMIC	10.919	Loss
Other_PLK_PLK1_PLK1_ST	Q14790	CASP8	P53350	PLK1	S305	I298V	298	Missense	distal	-7	no	12.108	12.273	PhosphoSitePlus	COSMIC	10.919	Up-regulation
Other_PLK_PLK1_PLK1_ST	Q14790	CASP8	P53350	PLK1	S305	C312Y	312	Missense	distal	7	no	12.108	12.095	PhosphoSitePlus	COSMIC;CCLE	10.919	Down-regulation
Other_PLK_PLK1_PLK1_ST	Q14790	CASP8	P53350	PLK1	S305	C312F	312	Missense	distal	7	no	12.108	12.109	PhosphoSitePlus	COSMIC	10.919	Up-regulation
Other_PLK_PLK1_PLK1_ST	Q14790	CASP8	P53350	PLK1	S305	D308V	308	Missense	distal	3	no	12.108	12.014	PhosphoSitePlus	COSMIC	10.919	Down-regulation
Other_PLK_PLK1_PLK1_ST	Q14790	CASP8	P53350	PLK1	S305	D303N	303	Missense	proximal	-2	no	12.108	10.865	PhosphoSitePlus	COSMIC	10.919	Loss
Other_PLK_PLK1_PLK1_ST	Q14790	CASP8	P53350	PLK1	S305	M307T	307	Missense	proximal	2	no	12.108	11.470	PhosphoSitePlus	COSMIC	10.919	Down-regulation
Other_PLK_PLK1_PLK1_ST	Q14790	CASP8	P53350	PLK1	S305	D308G	308	Missense	distal	3	no	12.108	11.865	PhosphoSitePlus	COSMIC	10.919	Down-regulation
Other_PLK_PLK1_PLK1_ST	Q14790	CASP8	P53350	PLK1	S347	C345Y	345	Missense	proximal	-2	no	7.850	11.360	EPSD	COSMIC	10.919	Gain
Other_PLK_PLK1_PLK1_ST	Q14790	CASP8	P53350	PLK1	S386	P379S	379	Missense	distal	-7	no	10.828	11.039	EPSD	COSMIC	10.919	Gain
Other_PLK_PLK1_PLK1_ST	Q14790	CASP8	P53350	PLK1	S386	P379Q	379	Missense	distal	-7	no	10.828	10.942	EPSD	COSMIC	10.919	Gain
Other_PLK_PLK1_PLK1_ST	Q14790	CASP8	P53350	PLK1	S386	P379T	379	Missense	distal	-7	no	10.828	11.030	EPSD	COSMIC	10.919	Gain
Other_PLK_PLK1_PLK1_ST	Q14790	CASP8	P53350	PLK1	S386	P388S	388	Missense	proximal	2	no	10.828	12.304	EPSD	COSMIC;CCLE	10.919	Gain
Other_PLK_PLK1_PLK1_ST	Q14790	CASP8	P53350	PLK1	S386	P388L	388	Missense	proximal	2	no	10.828	12.376	EPSD	COSMIC	10.919	Gain
Other_PLK_PLK1_PLK1_ST	Q6IBW4	NCAPH2	P53350	PLK1	T50	K48N	48	Missense	proximal	-2	no	11.914	13.943	EPSD	COSMIC	10.919	Up-regulation
Other_PLK_PLK1_PLK1_ST	Q6IBW4	NCAPH2	P53350	PLK1	S108	P111S	111	Missense	distal	3	no	12.360	12.338	EPSD	COSMIC	10.919	Down-regulation
Other_PLK_PLK1_PLK1_ST	Q6IBW4	NCAPH2	P53350	PLK1	T138	D136E	136	Missense	proximal	-2	no	12.911	12.517	EPSD	COSMIC	10.919	Down-regulation
Other_PLK_PLK1_PLK1_ST	Q6IBW4	NCAPH2	P53350	PLK1	S428	H424R	424	Missense	distal	-4	no	14.911	14.610	EPSD	COSMIC	10.919	Down-regulation
Other_PLK_PLK1_PLK1_ST	Q6IBW4	NCAPH2	P53350	PLK1	S428	A434T	434	Missense	distal	6	no	14.911	14.904	EPSD	COSMIC	10.919	Down-regulation
Other_PLK_PLK1_PLK1_ST	P14635	CCNB1	P53350	PLK1	S133	A136V	136	Missense	distal	3	no	12.250	12.578	PhosphoSitePlus;EPSD	COSMIC	10.919	Up-regulation
Other_PLK_PLK1_PLK1_ST	P14635	CCNB1	P53350	PLK1	S310	L306F	306	Missense	distal	-4	no	12.316	12.191	EPSD	COSMIC	10.919	Down-regulation
Other_PLK_PLK1_PLK1_ST	P14635	CCNB1	P53350	PLK1	S310	V317A	317	Missense	distal	7	no	12.316	12.293	EPSD	COSMIC	10.919	Down-regulation
Other_PLK_PLK1_PLK1_ST	P14635	CCNB1	P53350	PLK1	S413	S413C	413	Missense	central	0	yes	11.332	0.000	EPSD	COSMIC	10.919	Loss
Other_PLK_PLK1_PLK1_ST	Q71F23	CENPU	P53350	PLK1	T23	K21E	21	Missense	proximal	-2	no	9.357	12.234	EPSD	COSMIC	10.919	Gain
Other_PLK_PLK1_PLK1_ST	Q71F23	CENPU	P53350	PLK1	T27	R26T	26	Missense	proximal	-1	no	10.866	11.056	EPSD	COSMIC	10.919	Gain
Other_PLK_PLK1_PLK1_ST	Q71F23	CENPU	P53350	PLK1	T27	H28Y	28	Missense	proximal	1	no	10.866	11.371	EPSD	COSMIC	10.919	Gain
Other_PLK_PLK1_PLK1_ST	Q71F23	CENPU	P53350	PLK1	T27	K21E	21	Missense	distal	-6	no	10.866	11.440	EPSD	COSMIC	10.919	Gain
Other_PLK_PLK1_PLK1_ST	Q71F23	CENPU	P53350	PLK1	S29	R26T	26	Missense	distal	-3	no	12.278	11.823	EPSD	COSMIC	10.919	Down-regulation
Other_PLK_PLK1_PLK1_ST	Q71F23	CENPU	P53350	PLK1	S29	H28Y	28	Missense	proximal	-1	no	12.278	12.553	EPSD	COSMIC	10.919	Up-regulation
Other_PLK_PLK1_PLK1_ST	Q71F23	CENPU	P53350	PLK1	S50	V43M	43	Missense	distal	-7	no	11.152	11.019	EPSD	COSMIC;GDSC	10.919	Down-regulation
Other_PLK_PLK1_PLK1_ST	Q71F23	CENPU	P53350	PLK1	S50	S50A	50	Missense	central	0	yes	11.152	0.000	EPSD	COSMIC	10.919	Loss
Other_PLK_PLK1_PLK1_ST	Q71F23	CENPU	P53350	PLK1	S111	R106T	106	Missense	distal	-5	no	12.162	11.693	EPSD	COSMIC	10.919	Down-regulation
Other_PLK_PLK1_PLK1_ST	Q71F23	CENPU	P53350	PLK1	S111	S107G	107	Missense	distal	-4	no	12.162	11.509	EPSD	COSMIC	10.919	Down-regulation
Other_PLK_PLK1_PLK1_ST	Q71F23	CENPU	P53350	PLK1	S116	I123T	123	Missense	distal	7	no	11.729	11.682	EPSD	COSMIC	10.919	Down-regulation
Other_PLK_PLK1_PLK1_ST	Q71F23	CENPU	P53350	PLK1	S120	A125E	125	Missense	distal	5	no	12.755	11.896	EPSD	COSMIC	10.919	Down-regulation
Other_PLK_PLK1_PLK1_ST	Q71F23	CENPU	P53350	PLK1	S120	A125V	125	Missense	distal	5	no	12.755	12.016	EPSD	COSMIC	10.919	Down-regulation
Other_PLK_PLK1_PLK1_ST	Q71F23	CENPU	P53350	PLK1	S120	I123T	123	Missense	distal	3	no	12.755	12.588	EPSD	COSMIC	10.919	Down-regulation
Other_PLK_PLK1_PLK1_ST	Q71F23	CENPU	P53350	PLK1	S139	E144D	144	Missense	distal	5	no	13.173	13.614	EPSD	COSMIC;GDSC	10.919	Up-regulation
Other_PLK_PLK1_PLK1_ST	Q71F23	CENPU	P53350	PLK1	S139	R133G	133	Missense	distal	-6	no	13.173	13.074	EPSD	COSMIC	10.919	Down-regulation
Other_PLK_PLK1_PLK1_ST	Q71F23	CENPU	P53350	PLK1	S139	D138E	138	Missense	proximal	-1	no	13.173	12.376	EPSD	COSMIC	10.919	Down-regulation
Other_PLK_PLK1_PLK1_ST	Q71F23	CENPU	P53350	PLK1	S139	E140Q	140	Missense	proximal	1	no	13.173	13.296	EPSD	COSMIC	10.919	Up-regulation
Other_PLK_PLK1_PLK1_ST	Q71F23	CENPU	P53350	PLK1	S171	A169V	169	Missense	proximal	-2	no	11.972	11.932	EPSD	COSMIC	10.919	Down-regulation
Other_PLK_PLK1_PLK1_ST	Q71F23	CENPU	P53350	PLK1	S171	R166Q	166	Missense	distal	-5	no	11.972	11.233	EPSD	COSMIC	10.919	Down-regulation
Other_PLK_PLK1_PLK1_ST	Q71F23	CENPU	P53350	PLK1	S174	A169V	169	Missense	distal	-5	no	11.609	11.537	EPSD	COSMIC	10.919	Down-regulation
Other_PLK_PLK1_PLK1_ST	Q08050	FOXM1	P53350	PLK1	S28	E31K	31	Missense	distal	3	no	11.806	11.600	EPSD	COSMIC	10.919	Down-regulation
Other_PLK_PLK1_PLK1_ST	Q08050	FOXM1	P53350	PLK1	S306	V305L	305	Missense	proximal	-1	no	11.603	12.100	EPSD	COSMIC	10.919	Up-regulation
Other_PLK_PLK1_PLK1_ST	Q08050	FOXM1	P53350	PLK1	T354	R350Q	350	Missense	distal	-4	no	11.477	11.765	EPSD	COSMIC	10.919	Up-regulation
Other_PLK_PLK1_PLK1_ST	Q08050	FOXM1	P53350	PLK1	T354	R350L	350	Missense	distal	-4	no	11.477	11.850	EPSD	COSMIC	10.919	Up-regulation
Other_PLK_PLK1_PLK1_ST	Q08050	FOXM1	P53350	PLK1	S376	R373L	373	Missense	distal	-3	no	12.742	12.684	EPSD	COSMIC	10.919	Down-regulation
Other_PLK_PLK1_PLK1_ST	Q08050	FOXM1	P53350	PLK1	S506	S505L	505	Missense	proximal	-1	no	11.361	10.901	EPSD	COSMIC	10.919	Loss
Other_PLK_PLK1_PLK1_ST	Q08050	FOXM1	P53350	PLK1	S506	T510N	510	Missense	distal	4	no	11.361	11.318	EPSD	COSMIC;CCLE	10.919	Down-regulation
Other_PLK_PLK1_PLK1_ST	Q08050	FOXM1	P53350	PLK1	S582	P584S	584	Missense	proximal	2	no	10.128	11.604	EPSD	COSMIC	10.919	Gain
Other_PLK_PLK1_PLK1_ST	Q08050	FOXM1	P53350	PLK1	S591	S591F	591	Missense	central	0	yes	12.509	0.000	EPSD	COSMIC	10.919	Loss
Other_PLK_PLK1_PLK1_ST	Q08050	FOXM1	P53350	PLK1	S591	S589N	589	Missense	proximal	-2	no	12.509	13.919	EPSD	COSMIC	10.919	Up-regulation
Other_PLK_PLK1_PLK1_ST	Q08050	FOXM1	P53350	PLK1	S591	S586T	586	Missense	distal	-5	no	12.509	12.724	EPSD	COSMIC	10.919	Up-regulation
Other_PLK_PLK1_PLK1_ST	Q08050	FOXM1	P53350	PLK1	S591	P584S	584	Missense	distal	-7	no	12.509	12.720	EPSD	COSMIC	10.919	Up-regulation
Other_PLK_PLK1_PLK1_ST	Q08050	FOXM1	P53350	PLK1	S638	D636H	636	Missense	proximal	-2	no	11.396	8.209	EPSD	COSMIC	10.919	Loss
Other_PLK_PLK1_PLK1_ST	Q08050	FOXM1	P53350	PLK1	S638	S643P	643	Missense	distal	5	no	11.396	11.784	EPSD	COSMIC	10.919	Up-regulation
Other_PLK_PLK1_PLK1_ST	Q08050	FOXM1	P53350	PLK1	S638	V632G	632	Missense	distal	-6	no	11.396	11.125	EPSD	COSMIC	10.919	Down-regulation
Other_PLK_PLK1_PLK1_ST	Q08050	FOXM1	P53350	PLK1	S638	G633E	633	Missense	distal	-5	no	11.396	10.900	EPSD	COSMIC	10.919	Loss
Other_PLK_PLK1_PLK1_ST	Q08050	FOXM1	P53350	PLK1	S660	P663H	663	Missense	distal	3	no	12.382	12.368	EPSD	COSMIC	10.919	Down-regulation
Other_PLK_PLK1_PLK1_ST	Q08050	FOXM1	P53350	PLK1	S660	L659P	659	Missense	proximal	-1	no	12.382	11.668	EPSD	COSMIC	10.919	Down-regulation
Other_PLK_PLK1_PLK1_ST	Q08050	FOXM1	P53350	PLK1	S660	S666N	666	Missense	distal	6	no	12.382	12.433	EPSD	COSMIC	10.919	Up-regulation
Other_PLK_PLK1_PLK1_ST	Q08050	FOXM1	P53350	PLK1	S717	G721S	721	Missense	distal	4	no	13.455	13.540	EPSD	COSMIC	10.919	Up-regulation
Other_PLK_PLK1_PLK1_ST	Q08050	FOXM1	P53350	PLK1	S717	R716C	716	Missense	proximal	-1	no	13.455	12.531	EPSD	COSMIC	10.919	Down-regulation
Other_PLK_PLK1_PLK1_ST	Q08050	FOXM1	P53350	PLK1	S717	L722P	722	Missense	distal	5	no	13.455	14.189	EPSD	COSMIC	10.919	Up-regulation
Other_PLK_PLK1_PLK1_ST	Q08050	FOXM1	P53350	PLK1	S717	L724M	724	Missense	distal	7	no	13.455	13.525	EPSD	COSMIC;CCLE	10.919	Up-regulation
Other_PLK_PLK1_PLK1_ST	Q08050	FOXM1	P53350	PLK1	S717	A714T	714	Missense	distal	-3	no	13.455	13.309	EPSD	COSMIC	10.919	Down-regulation
Other_PLK_PLK1_PLK1_ST	Q08050	FOXM1	P53350	PLK1	T719	G721S	721	Missense	proximal	2	no	9.612	11.192	EPSD	COSMIC	10.919	Gain
Other_PLK_PLK1_PLK1_ST	Q08050	FOXM1	P53350	PLK1	T726	K733N	733	Missense	distal	7	no	11.208	11.213	EPSD	COSMIC	10.919	Up-regulation
Other_PLK_PLK1_PLK1_ST	Q08050	FOXM1	P53350	PLK1	T726	G721S	721	Missense	distal	-5	no	11.208	10.810	EPSD	COSMIC	10.919	Loss
Other_PLK_PLK1_PLK1_ST	Q08050	FOXM1	P53350	PLK1	T726	L722P	722	Missense	distal	-4	no	11.208	11.280	EPSD	COSMIC	10.919	Up-regulation
Other_PLK_PLK1_PLK1_ST	Q08050	FOXM1	P53350	PLK1	T726	L724M	724	Missense	proximal	-2	no	11.208	11.700	EPSD	COSMIC;CCLE	10.919	Up-regulation
Other_PLK_PLK1_PLK1_ST	Q08050	FOXM1	P53350	PLK1	T726	D725G	725	Missense	proximal	-1	no	11.208	8.619	EPSD	COSMIC	10.919	Loss
Other_PLK_PLK1_PLK1_ST	Q08050	FOXM1	P53350	PLK1	S730	K733N	733	Missense	distal	3	no	11.837	11.909	EPSD;PhosphoSitePlus	COSMIC	10.919	Up-regulation
Other_PLK_PLK1_PLK1_ST	Q08050	FOXM1	P53350	PLK1	S730	L724M	724	Missense	distal	-6	no	11.837	12.053	EPSD;PhosphoSitePlus	COSMIC;CCLE	10.919	Up-regulation
Other_PLK_PLK1_PLK1_ST	Q08050	FOXM1	P53350	PLK1	S730	D725G	725	Missense	distal	-5	no	11.837	11.992	EPSD;PhosphoSitePlus	COSMIC	10.919	Up-regulation
Other_PLK_PLK1_PLK1_ST	Q08050	FOXM1	P53350	PLK1	S739	S739N	739	Missense	central	0	yes	15.092	0.000	PhosphoSitePlus;EPSD	COSMIC	10.919	Loss
Other_PLK_PLK1_PLK1_ST	Q08050	FOXM1	P53350	PLK1	S739	K733N	733	Missense	distal	-6	no	15.092	15.350	PhosphoSitePlus;EPSD	COSMIC	10.919	Up-regulation
Other_PLK_PLK1_PLK1_ST	Q08050	FOXM1	P53350	PLK1	S739	E745K	745	Missense	distal	6	no	15.092	15.023	PhosphoSitePlus;EPSD	COSMIC	10.919	Down-regulation
Other_PLK_PLK1_PLK1_ST	Q02750	MAP2K1	P53350	PLK1	S218	S212N	212	Missense	distal	-6	no	13.962	13.765	EPSD;PhosphoSitePlus	COSMIC	10.919	Down-regulation
Other_PLK_PLK1_PLK1_ST	Q02750	MAP2K1	P53350	PLK1	S218	L215F	215	Missense	distal	-3	no	13.962	12.558	EPSD;PhosphoSitePlus	COSMIC	10.919	Down-regulation
Other_PLK_PLK1_PLK1_ST	Q02750	MAP2K1	P53350	PLK1	S218	G213V	213	Missense	distal	-5	no	13.962	13.774	EPSD;PhosphoSitePlus	COSMIC	10.919	Down-regulation
Other_PLK_PLK1_PLK1_ST	Q02750	MAP2K1	P53350	PLK1	S218	S218F	218	Missense	central	0	yes	13.962	0.000	EPSD;PhosphoSitePlus	COSMIC	10.919	Loss
Other_PLK_PLK1_PLK1_ST	Q02750	MAP2K1	P53350	PLK1	S222	L215F	215	Missense	distal	-7	no	14.742	14.590	PhosphoSitePlus;EPSD	COSMIC	10.919	Down-regulation
Other_PLK_PLK1_PLK1_ST	Q02750	MAP2K1	P53350	PLK1	S222	Y229H	229	Missense	distal	7	no	14.742	14.673	PhosphoSitePlus;EPSD	COSMIC	10.919	Down-regulation
Other_PLK_PLK1_PLK1_ST	Q02750	MAP2K1	P53350	PLK1	S222	S218F	218	Missense	distal	-4	no	14.742	14.424	PhosphoSitePlus;EPSD	COSMIC	10.919	Down-regulation
Other_PLK_PLK1_PLK1_ST	Q99741	CDC6	P53350	PLK1	T481	G483W	483	Missense	proximal	2	no	9.871	11.470	EPSD	COSMIC	10.919	Gain
Other_PLK_PLK1_PLK1_ST	Q9Y266	NUDC	P53350	PLK1	S136	G135D	135	Missense	proximal	-1	no	10.092	12.682	EPSD	COSMIC	10.919	Gain
Other_PLK_PLK1_PLK1_ST	Q9Y266	NUDC	P53350	PLK1	S231	G238S	238	Missense	distal	7	no	11.497	11.498	EPSD	COSMIC	10.919	Up-regulation
Other_PLK_PLK1_PLK1_ST	Q9Y266	NUDC	P53350	PLK1	S232	G238S	238	Missense	distal	6	no	10.915	11.119	EPSD	COSMIC	10.919	Gain
Other_PLK_PLK1_PLK1_ST	Q9Y266	NUDC	P53350	PLK1	S285	R284S	284	Missense	proximal	-1	no	11.476	12.413	EPSD	COSMIC	10.919	Up-regulation
Other_PLK_PLK1_PLK1_ST	Q9Y266	NUDC	P53350	PLK1	S326	S326F	326	Missense	central	0	yes	11.225	0.000	EPSD;PhosphoSitePlus	COSMIC;GDSC;CCLE	10.919	Loss
Other_PLK_PLK1_PLK1_ST	Q9Y2T1	AXIN2	P53350	PLK1	S16	D12N	12	Missense	distal	-4	no	11.048	11.107	EPSD	COSMIC	10.919	Up-regulation
Other_PLK_PLK1_PLK1_ST	Q9Y2T1	AXIN2	P53350	PLK1	S16	D12A	12	Missense	distal	-4	no	11.048	11.281	EPSD	COSMIC	10.919	Up-regulation
Other_PLK_PLK1_PLK1_ST	Q9Y2T1	AXIN2	P53350	PLK1	S16	P11L	11	Missense	distal	-5	no	11.048	11.449	EPSD	COSMIC	10.919	Up-regulation
Other_PLK_PLK1_PLK1_ST	Q9Y2T1	AXIN2	P53350	PLK1	S70	G63E	63	Missense	distal	-7	no	10.463	11.098	EPSD	COSMIC	10.919	Gain
Other_PLK_PLK1_PLK1_ST	Q9Y2T1	AXIN2	P53350	PLK1	S70	G63W	63	Missense	distal	-7	no	10.463	11.248	EPSD	COSMIC	10.919	Gain
Other_PLK_PLK1_PLK1_ST	Q9Y2T1	AXIN2	P53350	PLK1	S244	T246I	246	Missense	proximal	2	no	10.010	11.072	EPSD	COSMIC	10.919	Gain
Other_PLK_PLK1_PLK1_ST	Q9Y2T1	AXIN2	P53350	PLK1	S311	S317T	317	Missense	distal	6	no	16.971	17.247	PhosphoSitePlus	COSMIC	10.919	Up-regulation
Other_PLK_PLK1_PLK1_ST	Q9Y2T1	AXIN2	P53350	PLK1	S407	S413L	413	Missense	distal	6	no	11.417	11.456	EPSD	COSMIC	10.919	Up-regulation
Other_PLK_PLK1_PLK1_ST	Q9Y2T1	AXIN2	P53350	PLK1	S407	R414Q	414	Missense	distal	7	no	11.417	11.432	EPSD	COSMIC	10.919	Up-regulation
Other_PLK_PLK1_PLK1_ST	Q9Y2T1	AXIN2	P53350	PLK1	S407	N412S	412	Missense	distal	5	no	11.417	12.020	EPSD	COSMIC	10.919	Up-regulation
Other_PLK_PLK1_PLK1_ST	Q9Y2T1	AXIN2	P53350	PLK1	S407	L409F	409	Missense	proximal	2	no	11.417	10.794	EPSD	COSMIC	10.919	Loss
Other_PLK_PLK1_PLK1_ST	Q9Y2T1	AXIN2	P53350	PLK1	S407	E400D	400	Missense	distal	-7	no	11.417	11.128	EPSD	COSMIC	10.919	Down-regulation
Other_PLK_PLK1_PLK1_ST	Q9Y2T1	AXIN2	P53350	PLK1	S407	E405D	405	Missense	proximal	-2	no	11.417	11.811	EPSD	COSMIC	10.919	Up-regulation
Other_PLK_PLK1_PLK1_ST	Q9Y2T1	AXIN2	P53350	PLK1	S407	E408K	408	Missense	proximal	1	no	11.417	10.966	EPSD	COSMIC	10.919	Down-regulation
Other_PLK_PLK1_PLK1_ST	Q9Y2T1	AXIN2	P53350	PLK1	S407	T410I	410	Missense	distal	3	no	11.417	11.583	EPSD	COSMIC	10.919	Up-regulation
Other_PLK_PLK1_PLK1_ST	Q9Y2T1	AXIN2	P53350	PLK1	S461	R465H	465	Missense	distal	4	no	10.878	11.301	EPSD	COSMIC	10.919	Gain
Other_PLK_PLK1_PLK1_ST	Q9Y2T1	AXIN2	P53350	PLK1	S461	P455S	455	Missense	distal	-6	no	10.878	11.501	EPSD	COSMIC	10.919	Gain
Other_PLK_PLK1_PLK1_ST	Q9Y2T1	AXIN2	P53350	PLK1	S461	S464F	464	Missense	distal	3	no	10.878	10.937	EPSD	COSMIC	10.919	Gain
Other_PLK_PLK1_PLK1_ST	Q8TEP8	CEP192	P53350	PLK1	T223	Q221E	221	Missense	proximal	-2	no	9.604	12.264	EPSD	COSMIC	10.919	Gain
Other_PLK_PLK1_PLK1_ST	Q8TEP8	CEP192	P53350	PLK1	S408	G410V	410	Missense	proximal	2	no	9.866	11.650	EPSD	COSMIC	10.919	Gain
Other_PLK_PLK1_PLK1_ST	Q8TEP8	CEP192	P53350	PLK1	S1602	L1596F	1596	Missense	distal	-6	no	12.525	12.342	EPSD	COSMIC	10.919	Down-regulation
Other_PLK_PLK1_PLK1_ST	Q99640	PKMYT1	P53350	PLK1	S426	S425N	425	Missense	proximal	-1	no	15.084	14.944	EPSD;PhosphoSitePlus	COSMIC	10.919	Down-regulation
Other_PLK_PLK1_PLK1_ST	Q99640	PKMYT1	P53350	PLK1	S469	D467G	467	Missense	proximal	-2	no	13.246	9.924	EPSD	COSMIC	10.919	Loss
Other_PLK_PLK1_PLK1_ST	O60216	RAD21	P53350	PLK1	S40	I45V	45	Missense	distal	5	no	12.100	11.630	EPSD	COSMIC	10.919	Down-regulation
Other_PLK_PLK1_PLK1_ST	O60216	RAD21	P53350	PLK1	S40	F33L	33	Missense	distal	-7	no	12.100	12.252	EPSD	COSMIC	10.919	Up-regulation
Other_PLK_PLK1_PLK1_ST	O60216	RAD21	P53350	PLK1	S40	P47Q	47	Missense	distal	7	no	12.100	12.103	EPSD	COSMIC	10.919	Up-regulation
Other_PLK_PLK1_PLK1_ST	O60216	RAD21	P53350	PLK1	S40	E42K	42	Missense	proximal	2	no	12.100	11.930	EPSD	COSMIC;GDSC;CCLE	10.919	Down-regulation
Other_PLK_PLK1_PLK1_ST	O60216	RAD21	P53350	PLK1	S40	I44V	44	Missense	distal	4	no	12.100	12.829	EPSD	COSMIC	10.919	Up-regulation
Other_PLK_PLK1_PLK1_ST	O60216	RAD21	P53350	PLK1	S40	I44M	44	Missense	distal	4	no	12.100	12.342	EPSD	COSMIC	10.919	Up-regulation
Other_PLK_PLK1_PLK1_ST	O60216	RAD21	P53350	PLK1	S43	I45V	45	Missense	proximal	2	no	10.970	10.752	EPSD	COSMIC	10.919	Loss
Other_PLK_PLK1_PLK1_ST	O60216	RAD21	P53350	PLK1	S43	P47Q	47	Missense	distal	4	no	10.970	10.876	EPSD	COSMIC	10.919	Loss
Other_PLK_PLK1_PLK1_ST	O60216	RAD21	P53350	PLK1	S43	E42K	42	Missense	proximal	-1	no	10.970	10.398	EPSD	COSMIC;GDSC;CCLE	10.919	Loss
Other_PLK_PLK1_PLK1_ST	O60216	RAD21	P53350	PLK1	S43	I44V	44	Missense	proximal	1	no	10.970	10.778	EPSD	COSMIC	10.919	Loss
Other_PLK_PLK1_PLK1_ST	O60216	RAD21	P53350	PLK1	S43	I44M	44	Missense	proximal	1	no	10.970	11.934	EPSD	COSMIC	10.919	Up-regulation
Other_PLK_PLK1_PLK1_ST	O60216	RAD21	P53350	PLK1	S46	I44V	44	Missense	proximal	-2	no	10.822	11.426	EPSD	COSMIC	10.919	Gain
Other_PLK_PLK1_PLK1_ST	O60216	RAD21	P53350	PLK1	S46	I44M	44	Missense	proximal	-2	no	10.822	10.930	EPSD	COSMIC	10.919	Gain
Other_PLK_PLK1_PLK1_ST	O60216	RAD21	P53350	PLK1	S134	I127M	127	Missense	distal	-7	no	11.727	11.759	EPSD	COSMIC	10.919	Up-regulation
Other_PLK_PLK1_PLK1_ST	O60216	RAD21	P53350	PLK1	S134	A130T	130	Missense	distal	-4	no	11.727	11.325	EPSD	COSMIC	10.919	Down-regulation
Other_PLK_PLK1_PLK1_ST	O60216	RAD21	P53350	PLK1	S134	D128Y	128	Missense	distal	-6	no	11.727	10.957	EPSD	COSMIC	10.919	Down-regulation
Other_PLK_PLK1_PLK1_ST	O60216	RAD21	P53350	PLK1	S138	T144P	144	Missense	distal	6	no	11.704	11.572	EPSD	COSMIC	10.919	Down-regulation
Other_PLK_PLK1_PLK1_ST	O60216	RAD21	P53350	PLK1	T144	T144P	144	Missense	central	0	yes	15.810	0.000	EPSD	COSMIC	10.919	Loss
Other_PLK_PLK1_PLK1_ST	O60216	RAD21	P53350	PLK1	T144	R146T	146	Missense	proximal	2	no	15.810	15.897	EPSD	COSMIC	10.919	Up-regulation
Other_PLK_PLK1_PLK1_ST	O60216	RAD21	P53350	PLK1	S153	R146T	146	Missense	distal	-7	no	14.190	14.678	EPSD	COSMIC	10.919	Up-regulation
Other_PLK_PLK1_PLK1_ST	O60216	RAD21	P53350	PLK1	S153	I154V	154	Missense	proximal	1	no	14.190	13.999	EPSD	COSMIC	10.919	Down-regulation
Other_PLK_PLK1_PLK1_ST	O60216	RAD21	P53350	PLK1	S280	P283L	283	Missense	distal	3	no	10.971	10.802	EPSD	COSMIC	10.919	Loss
Other_PLK_PLK1_PLK1_ST	O60216	RAD21	P53350	PLK1	S280	P283S	283	Missense	distal	3	no	10.971	10.949	EPSD	COSMIC	10.919	Down-regulation
Other_PLK_PLK1_PLK1_ST	O60216	RAD21	P53350	PLK1	S280	P286S	286	Missense	distal	6	no	10.971	10.826	EPSD	COSMIC	10.919	Loss
Other_PLK_PLK1_PLK1_ST	O60216	RAD21	P53350	PLK1	S280	P286T	286	Missense	distal	6	no	10.971	11.102	EPSD	COSMIC	10.919	Up-regulation
Other_PLK_PLK1_PLK1_ST	O60216	RAD21	P53350	PLK1	S280	P278S	278	Missense	proximal	-2	no	10.971	11.555	EPSD	COSMIC	10.919	Up-regulation
Other_PLK_PLK1_PLK1_ST	O60216	RAD21	P53350	PLK1	T312	D310E	310	Missense	proximal	-2	no	11.659	11.265	EPSD	COSMIC	10.919	Down-regulation
Other_PLK_PLK1_PLK1_ST	O60216	RAD21	P53350	PLK1	T312	P308L	308	Missense	distal	-4	no	11.659	11.587	EPSD	COSMIC	10.919	Down-regulation
Other_PLK_PLK1_PLK1_ST	O60216	RAD21	P53350	PLK1	S328	S334I	334	Missense	distal	6	no	12.730	12.732	EPSD	COSMIC	10.919	Up-regulation
Other_PLK_PLK1_PLK1_ST	O60216	RAD21	P53350	PLK1	S342	L341R	341	Missense	proximal	-1	no	11.135	10.658	EPSD	COSMIC;GDSC;CCLE	10.919	Loss
Other_PLK_PLK1_PLK1_ST	O60216	RAD21	P53350	PLK1	S342	D346H	346	Missense	distal	4	no	11.135	10.611	EPSD	COSMIC	10.919	Loss
Other_PLK_PLK1_PLK1_ST	O60216	RAD21	P53350	PLK1	S342	R338T	338	Missense	distal	-4	no	11.135	11.339	EPSD	COSMIC	10.919	Up-regulation
Other_PLK_PLK1_PLK1_ST	O60216	RAD21	P53350	PLK1	S345	L341R	341	Missense	distal	-4	no	14.335	13.962	EPSD	COSMIC;GDSC;CCLE	10.919	Down-regulation
Other_PLK_PLK1_PLK1_ST	O60216	RAD21	P53350	PLK1	S345	D346H	346	Missense	proximal	1	no	14.335	13.633	EPSD	COSMIC	10.919	Down-regulation
Other_PLK_PLK1_PLK1_ST	O60216	RAD21	P53350	PLK1	S345	R338T	338	Missense	distal	-7	no	14.335	14.823	EPSD	COSMIC	10.919	Up-regulation
Other_PLK_PLK1_PLK1_ST	O60216	RAD21	P53350	PLK1	S459	R460I	460	Missense	proximal	1	no	8.096	11.019	EPSD	COSMIC	10.919	Gain
Other_PLK_PLK1_PLK1_ST	O60216	RAD21	P53350	PLK1	S466	D464N	464	Missense	proximal	-2	no	11.619	10.377	EPSD	COSMIC	10.919	Loss
Other_PLK_PLK1_PLK1_ST	O60216	RAD21	P53350	PLK1	S466	R460S	460	Missense	distal	-6	no	11.619	12.067	EPSD	COSMIC	10.919	Up-regulation
Other_PLK_PLK1_PLK1_ST	O60216	RAD21	P53350	PLK1	S466	R460I	460	Missense	distal	-6	no	11.619	12.135	EPSD	COSMIC	10.919	Up-regulation
Other_PLK_PLK1_PLK1_ST	O60216	RAD21	P53350	PLK1	S466	P472S	472	Missense	distal	6	no	11.619	11.475	EPSD	COSMIC	10.919	Down-regulation
Other_PLK_PLK1_PLK1_ST	O60216	RAD21	P53350	PLK1	S466	A467T	467	Missense	proximal	1	no	11.619	12.081	EPSD	COSMIC	10.919	Up-regulation
Other_PLK_PLK1_PLK1_ST	O60216	RAD21	P53350	PLK1	S466	S459N	459	Missense	distal	-7	no	11.619	11.409	EPSD	COSMIC	10.919	Down-regulation
Other_PLK_PLK1_PLK1_ST	O60216	RAD21	P53350	PLK1	S618	L611R	611	Missense	distal	-7	no	11.372	11.180	EPSD	COSMIC	10.919	Down-regulation
Other_PLK_PLK1_PLK1_ST	O60216	RAD21	P53350	PLK1	S618	P624L	624	Missense	distal	6	no	11.372	11.268	EPSD	COSMIC	10.919	Down-regulation
Other_PLK_PLK1_PLK1_ST	O60216	RAD21	P53350	PLK1	S618	Y617C	617	Missense	proximal	-1	no	11.372	9.176	EPSD	COSMIC	10.919	Loss
Other_PLK_PLK1_PLK1_ST	O60216	RAD21	P53350	PLK1	S618	I620T	620	Missense	proximal	2	no	11.372	10.311	EPSD	COSMIC	10.919	Loss
Other_PLK_PLK1_PLK1_ST	O43379	WDR62	P53350	PLK1	S20	V21F	21	Missense	proximal	1	no	11.263	12.743	EPSD	COSMIC	10.919	Up-regulation
Other_PLK_PLK1_PLK1_ST	O43379	WDR62	P53350	PLK1	S205	F206L	206	Missense	proximal	1	no	12.062	10.982	EPSD	COSMIC	10.919	Down-regulation
Other_PLK_PLK1_PLK1_ST	O43379	WDR62	P53350	PLK1	S205	L204H	204	Missense	proximal	-1	no	12.062	12.583	EPSD	COSMIC	10.919	Up-regulation
Other_PLK_PLK1_PLK1_ST	O43379	WDR62	P53350	PLK1	S207	F206L	206	Missense	proximal	-1	no	11.042	11.121	EPSD	COSMIC	10.919	Up-regulation
Other_PLK_PLK1_PLK1_ST	O43379	WDR62	P53350	PLK1	S207	L204H	204	Missense	distal	-3	no	11.042	10.428	EPSD	COSMIC	10.919	Loss
Other_PLK_PLK1_PLK1_ST	O43379	WDR62	P53350	PLK1	S210	F206L	206	Missense	distal	-4	no	11.425	11.549	EPSD	COSMIC	10.919	Up-regulation
Other_PLK_PLK1_PLK1_ST	O43379	WDR62	P53350	PLK1	S210	L204H	204	Missense	distal	-6	no	11.425	11.771	EPSD	COSMIC	10.919	Up-regulation
Other_PLK_PLK1_PLK1_ST	O43379	WDR62	P53350	PLK1	S211	F206L	206	Missense	distal	-5	no	11.779	12.704	EPSD	COSMIC	10.919	Up-regulation
Other_PLK_PLK1_PLK1_ST	O43379	WDR62	P53350	PLK1	S211	L204H	204	Missense	distal	-7	no	11.779	11.967	EPSD	COSMIC	10.919	Up-regulation
Other_PLK_PLK1_PLK1_ST	O43379	WDR62	P53350	PLK1	S675	G674R	674	Missense	proximal	-1	no	10.374	11.234	EPSD	COSMIC	10.919	Gain
Other_PLK_PLK1_PLK1_ST	O43379	WDR62	P53350	PLK1	T781	P777S	777	Missense	distal	-4	no	11.155	11.277	EPSD	COSMIC	10.919	Up-regulation
Other_PLK_PLK1_PLK1_ST	O43379	WDR62	P53350	PLK1	S897	E895Q	895	Missense	proximal	-2	no	14.056	11.397	PhosphoSitePlus	COSMIC	10.919	Down-regulation
Other_PLK_PLK1_PLK1_ST	O43379	WDR62	P53350	PLK1	S935	L942F	942	Missense	distal	7	no	11.137	11.208	EPSD	COSMIC	10.919	Up-regulation
Other_PLK_PLK1_PLK1_ST	O43379	WDR62	P53350	PLK1	S987	E994Q	994	Missense	distal	7	no	12.627	12.680	EPSD	COSMIC	10.919	Up-regulation
Other_PLK_PLK1_PLK1_ST	O43379	WDR62	P53350	PLK1	S987	P988R	988	Missense	proximal	1	no	12.627	10.342	EPSD	COSMIC	10.919	Loss
Other_PLK_PLK1_PLK1_ST	O43379	WDR62	P53350	PLK1	S992	E994Q	994	Missense	proximal	2	no	11.431	11.620	EPSD	COSMIC	10.919	Up-regulation
Other_PLK_PLK1_PLK1_ST	O43379	WDR62	P53350	PLK1	S992	P988R	988	Missense	distal	-4	no	11.431	10.986	EPSD	COSMIC	10.919	Down-regulation
Other_PLK_PLK1_PLK1_ST	O43379	WDR62	P53350	PLK1	S1095	T1096M	1096	Missense	proximal	1	no	9.573	11.704	EPSD	COSMIC	10.919	Gain
Other_PLK_PLK1_PLK1_ST	O43379	WDR62	P53350	PLK1	T1159	A1152T	1152	Missense	distal	-7	no	14.045	14.389	EPSD	COSMIC	10.919	Up-regulation
Other_PLK_PLK1_PLK1_ST	O43379	WDR62	P53350	PLK1	T1159	R1164C	1164	Missense	distal	5	no	14.045	13.829	EPSD	COSMIC	10.919	Down-regulation
Other_PLK_PLK1_PLK1_ST	O43379	WDR62	P53350	PLK1	T1159	K1155N	1155	Missense	distal	-4	no	14.045	14.303	EPSD	COSMIC	10.919	Up-regulation
Other_PLK_PLK1_PLK1_ST	O43379	WDR62	P53350	PLK1	S1226	S1232N	1232	Missense	distal	6	no	10.908	10.959	EPSD	COSMIC	10.919	Gain
Other_PLK_PLK1_PLK1_ST	O43379	WDR62	P53350	PLK1	S1226	G1230S	1230	Missense	distal	4	no	10.908	10.993	EPSD	COSMIC	10.919	Gain
Other_PLK_PLK1_PLK1_ST	O43379	WDR62	P53350	PLK1	S1228	G1230S	1230	Missense	proximal	2	no	9.504	11.085	EPSD	COSMIC	10.919	Gain
Other_PLK_PLK1_PLK1_ST	O43379	WDR62	P53350	PLK1	S1330	A1323T	1323	Missense	distal	-7	no	10.859	11.204	EPSD	COSMIC	10.919	Gain
Other_PLK_PLK1_PLK1_ST	P01106	MYC	P53350	PLK1	S159	K157N	157	Missense	proximal	-2	no	9.670	11.699	EPSD	COSMIC	10.919	Gain
Other_PLK_PLK1_PLK1_ST	P01106	MYC	P53350	PLK1	S161	A154T	154	Missense	distal	-7	no	10.605	10.950	EPSD	COSMIC	10.919	Gain
Other_PLK_PLK1_PLK1_ST	P01106	MYC	P53350	PLK1	S161	G160D	160	Missense	proximal	-1	no	10.605	13.195	EPSD	COSMIC	10.919	Gain
Other_PLK_PLK1_PLK1_ST	P01106	MYC	P53350	PLK1	S161	S159N	159	Missense	proximal	-2	no	10.605	12.014	EPSD	COSMIC	10.919	Gain
Other_PLK_PLK1_PLK1_ST	P01106	MYC	P53350	PLK1	S161	D158G	158	Missense	distal	-3	no	10.605	11.087	EPSD	COSMIC	10.919	Gain
Other_PLK_PLK1_PLK1_ST	P01106	MYC	P53350	PLK1	T173	S175N	175	Missense	proximal	2	no	10.802	11.015	EPSD	COSMIC	10.919	Gain
Other_PLK_PLK1_PLK1_ST	P01106	MYC	P53350	PLK1	T173	L176F	176	Missense	distal	3	no	10.802	11.008	EPSD	COSMIC	10.919	Gain
Other_PLK_PLK1_PLK1_ST	P01106	MYC	P53350	PLK1	T173	C171S	171	Missense	proximal	-2	no	10.802	13.201	EPSD	COSMIC	10.919	Gain
Other_PLK_PLK1_PLK1_ST	P01106	MYC	P53350	PLK1	T173	R166H	166	Missense	distal	-7	no	10.802	11.181	EPSD	COSMIC	10.919	Gain
Other_PLK_PLK1_PLK1_ST	P01106	MYC	P53350	PLK1	T173	V170I	170	Missense	distal	-3	no	10.802	11.077	EPSD	COSMIC	10.919	Gain
Other_PLK_PLK1_PLK1_ST	P01106	MYC	P53350	PLK1	T173	S174T	174	Missense	proximal	1	no	10.802	11.394	EPSD	COSMIC;CCLE	10.919	Gain
Other_PLK_PLK1_PLK1_ST	P01106	MYC	P53350	PLK1	T173	L178V	178	Missense	distal	5	no	10.802	10.976	EPSD	COSMIC;CCLE	10.919	Gain
Other_PLK_PLK1_PLK1_ST	P01106	MYC	P53350	PLK1	T173	C171Y	171	Missense	proximal	-2	no	10.802	14.311	EPSD	COSMIC	10.919	Gain
Other_PLK_PLK1_PLK1_ST	P01106	MYC	P53350	PLK1	T173	S174Y	174	Missense	proximal	1	no	10.802	11.540	EPSD	COSMIC	10.919	Gain
Other_PLK_PLK1_PLK1_ST	P01106	MYC	P53350	PLK1	T173	S174N	174	Missense	proximal	1	no	10.802	11.542	EPSD	COSMIC	10.919	Gain
Other_PLK_PLK1_PLK1_ST	P01106	MYC	P53350	PLK1	T173	L176V	176	Missense	distal	3	no	10.802	11.100	EPSD	COSMIC	10.919	Gain
Other_PLK_PLK1_PLK1_ST	P01106	MYC	P53350	PLK1	S203	P205S	205	Missense	proximal	2	no	9.975	11.451	EPSD	COSMIC	10.919	Gain
Other_PLK_PLK1_PLK1_ST	P01106	MYC	P53350	PLK1	S314	P313L	313	Missense	proximal	-1	no	10.891	11.605	EPSD	COSMIC	10.919	Gain
Other_PLK_PLK1_PLK1_ST	P01106	MYC	P53350	PLK1	S314	A311G	311	Missense	distal	-3	no	10.891	11.141	EPSD	COSMIC	10.919	Gain
Other_PLK_PLK1_PLK1_ST	P01106	MYC	P53350	PLK1	S329	K326R	326	Missense	distal	-3	no	13.063	13.523	EPSD	COSMIC	10.919	Up-regulation
Other_PLK_PLK1_PLK1_ST	P01106	MYC	P53350	PLK1	S329	V325D	325	Missense	distal	-4	no	13.063	12.969	EPSD	COSMIC	10.919	Down-regulation
Other_PLK_PLK1_PLK1_ST	P01106	MYC	P53350	PLK1	S329	D328G	328	Missense	proximal	-1	no	13.063	10.473	EPSD	COSMIC	10.919	Loss
Other_PLK_PLK1_PLK1_ST	P01106	MYC	P53350	PLK1	S329	V325L	325	Missense	distal	-4	no	13.063	12.970	EPSD	COSMIC	10.919	Down-regulation
Other_PLK_PLK1_PLK1_ST	P01106	MYC	P53350	PLK1	S329	V330L	330	Missense	proximal	1	no	13.063	13.462	EPSD	COSMIC	10.919	Up-regulation
Other_PLK_PLK1_PLK1_ST	P01106	MYC	P53350	PLK1	S329	I336V	336	Missense	distal	7	no	13.063	13.079	EPSD	COSMIC	10.919	Up-regulation
Other_PLK_PLK1_PLK1_ST	P01106	MYC	P53350	PLK1	S329	L333P	333	Missense	distal	4	no	13.063	13.353	EPSD	COSMIC	10.919	Up-regulation
Other_PLK_PLK1_PLK1_ST	P01106	MYC	P53350	PLK1	S329	L333V	333	Missense	distal	4	no	13.063	13.213	EPSD	COSMIC	10.919	Up-regulation
Other_PLK_PLK1_PLK1_ST	P01106	MYC	P53350	PLK1	S337	V330L	330	Missense	distal	-7	no	11.125	11.117	EPSD	COSMIC	10.919	Down-regulation
Other_PLK_PLK1_PLK1_ST	P01106	MYC	P53350	PLK1	S337	I336V	336	Missense	proximal	-1	no	11.125	10.152	EPSD	COSMIC	10.919	Loss
Other_PLK_PLK1_PLK1_ST	P01106	MYC	P53350	PLK1	S337	L333P	333	Missense	distal	-4	no	11.125	11.197	EPSD	COSMIC	10.919	Up-regulation
Other_PLK_PLK1_PLK1_ST	P01106	MYC	P53350	PLK1	S337	L333V	333	Missense	distal	-4	no	11.125	11.218	EPSD	COSMIC	10.919	Up-regulation
Other_PLK_PLK1_PLK1_ST	Q92994	BRF1	P53350	PLK1	S226	L228I	228	Missense	proximal	2	no	11.268	11.618	EPSD	COSMIC	10.919	Up-regulation
Other_PLK_PLK1_PLK1_ST	Q92994	BRF1	P53350	PLK1	S226	L233P	233	Missense	distal	7	no	11.268	11.297	EPSD	COSMIC	10.919	Up-regulation
Other_PLK_PLK1_PLK1_ST	Q92994	BRF1	P53350	PLK1	S226	A232V	232	Missense	distal	6	no	11.268	11.093	EPSD	COSMIC	10.919	Down-regulation
Other_PLK_PLK1_PLK1_ST	Q92994	BRF1	P53350	PLK1	S226	P225H	225	Missense	proximal	-1	no	11.268	12.503	EPSD	COSMIC	10.919	Up-regulation
Other_PLK_PLK1_PLK1_ST	Q92994	BRF1	P53350	PLK1	S226	C229R	229	Missense	distal	3	no	11.268	11.209	EPSD	COSMIC	10.919	Down-regulation
Other_PLK_PLK1_PLK1_ST	Q92994	BRF1	P53350	PLK1	S226	L228R	228	Missense	proximal	2	no	11.268	10.469	EPSD	COSMIC	10.919	Loss
Other_PLK_PLK1_PLK1_ST	Q92994	BRF1	P53350	PLK1	S226	G227D	227	Missense	proximal	1	no	11.268	11.266	EPSD	COSMIC	10.919	Down-regulation
Other_PLK_PLK1_PLK1_ST	Q92994	BRF1	P53350	PLK1	S226	C229S	229	Missense	distal	3	no	11.268	11.333	EPSD	COSMIC	10.919	Up-regulation
Other_PLK_PLK1_PLK1_ST	Q92994	BRF1	P53350	PLK1	T270	E268K	268	Missense	proximal	-2	no	12.520	9.642	EPSD	COSMIC	10.919	Loss
Other_PLK_PLK1_PLK1_ST	Q92994	BRF1	P53350	PLK1	T355	T355I	355	Missense	central	0	yes	14.256	0.000	EPSD	COSMIC	10.919	Loss
Other_PLK_PLK1_PLK1_ST	Q92994	BRF1	P53350	PLK1	S442	G443V	443	Missense	proximal	1	no	14.257	14.888	EPSD	COSMIC	10.919	Up-regulation
Other_PLK_PLK1_PLK1_ST	Q92994	BRF1	P53350	PLK1	S450	G443V	443	Missense	distal	-7	no	13.364	13.764	PhosphoSitePlus	COSMIC	10.919	Up-regulation
Other_PLK_PLK1_PLK1_ST	Q92994	BRF1	P53350	PLK1	S541	V542A	542	Missense	proximal	1	no	12.393	10.955	EPSD	COSMIC	10.919	Down-regulation
Other_PLK_PLK1_PLK1_ST	Q92994	BRF1	P53350	PLK1	S541	S536I	536	Missense	distal	-5	no	12.393	12.761	EPSD	COSMIC	10.919	Up-regulation
Other_PLK_PLK1_PLK1_ST	Q92994	BRF1	P53350	PLK1	S631	P633S	633	Missense	proximal	2	no	9.789	11.266	EPSD	COSMIC	10.919	Gain
Other_PLK_PLK1_PLK1_ST	P25490	YY1	P53350	PLK1	S118	A123T	123	Missense	distal	5	no	12.737	11.565	EPSD	COSMIC	10.919	Down-regulation
Other_PLK_PLK1_PLK1_ST	P25490	YY1	P53350	PLK1	S247	P249S	249	Missense	proximal	2	no	12.020	13.496	EPSD	COSMIC	10.919	Up-regulation
Other_PLK_PLK1_PLK1_ST	P25490	YY1	P53350	PLK1	S247	E253K	253	Missense	distal	6	no	12.020	11.951	EPSD	COSMIC	10.919	Down-regulation
Other_PLK_PLK1_PLK1_ST	P25490	YY1	P53350	PLK1	S247	I243T	243	Missense	distal	-4	no	12.020	11.624	EPSD	COSMIC	10.919	Down-regulation
Other_PLK_PLK1_PLK1_ST	P25490	YY1	P53350	PLK1	S252	P249S	249	Missense	distal	-3	no	12.049	12.467	EPSD	COSMIC	10.919	Up-regulation
Other_PLK_PLK1_PLK1_ST	P25490	YY1	P53350	PLK1	S252	E253K	253	Missense	proximal	1	no	12.049	11.599	EPSD	COSMIC	10.919	Down-regulation
Other_PLK_PLK1_PLK1_ST	O96017	CHEK2	P53350	PLK1	T26	V25I	25	Missense	proximal	-1	no	12.296	13.270	EPSD	COSMIC	10.919	Up-regulation
Other_PLK_PLK1_PLK1_ST	O96017	CHEK2	P53350	PLK1	T26	S19L	19	Missense	distal	-7	no	12.296	11.992	EPSD	COSMIC	10.919	Down-regulation
Other_PLK_PLK1_PLK1_ST	O96017	CHEK2	P53350	PLK1	S52	S50N	50	Missense	proximal	-2	no	9.572	10.981	EPSD	COSMIC	10.919	Gain
Other_PLK_PLK1_PLK1_ST	O96017	CHEK2	P53350	PLK1	T68	Q69R	69	Missense	proximal	1	no	11.890	9.911	PhosphoSitePlus;EPSD	COSMIC	10.919	Loss
Other_PLK_PLK1_PLK1_ST	O96017	CHEK2	P53350	PLK1	S120	C124Y	124	Missense	distal	4	no	10.850	11.133	EPSD	COSMIC	10.919	Gain
Other_PLK_PLK1_PLK1_ST	O96017	CHEK2	P53350	PLK1	S164	E161Q	161	Missense	distal	-3	no	11.977	12.303	EPSD;PhosphoSitePlus	COSMIC	10.919	Up-regulation
Other_PLK_PLK1_PLK1_ST	O96017	CHEK2	P53350	PLK1	S164	H163D	163	Missense	proximal	-1	no	11.977	12.709	EPSD;PhosphoSitePlus	COSMIC	10.919	Up-regulation
Other_PLK_PLK1_PLK1_ST	O96017	CHEK2	P53350	PLK1	S164	T168S	168	Missense	distal	4	no	11.977	12.169	EPSD;PhosphoSitePlus	COSMIC	10.919	Up-regulation
Other_PLK_PLK1_PLK1_ST	O96017	CHEK2	P53350	PLK1	S164	S164N	164	Missense	central	0	yes	11.977	0.000	EPSD;PhosphoSitePlus	COSMIC;CCLE	10.919	Loss
Other_PLK_PLK1_PLK1_ST	O96017	CHEK2	P53350	PLK1	S164	Y159C	159	Missense	distal	-5	no	11.977	11.897	EPSD;PhosphoSitePlus	COSMIC	10.919	Down-regulation
Other_PLK_PLK1_PLK1_ST	O96017	CHEK2	P53350	PLK1	S164	F169L	169	Missense	distal	5	no	11.977	11.536	EPSD;PhosphoSitePlus	COSMIC;CCLE	10.919	Down-regulation
Other_PLK_PLK1_PLK1_ST	O96017	CHEK2	P53350	PLK1	S164	V170I	170	Missense	distal	6	no	11.977	11.870	EPSD;PhosphoSitePlus	COSMIC	10.919	Down-regulation
Other_PLK_PLK1_PLK1_ST	O96017	CHEK2	P53350	PLK1	S164	I160M	160	Missense	distal	-4	no	11.977	11.667	EPSD;PhosphoSitePlus	COSMIC	10.919	Down-regulation
Other_PLK_PLK1_PLK1_ST	O96017	CHEK2	P53350	PLK1	S194	N196I	196	Missense	proximal	2	no	10.796	11.004	EPSD	COSMIC	10.919	Gain
Other_PLK_PLK1_PLK1_ST	O96017	CHEK2	P53350	PLK1	T205	V198L	198	Missense	distal	-7	no	12.210	12.202	EPSD;PhosphoSitePlus	COSMIC	10.919	Down-regulation
Other_PLK_PLK1_PLK1_ST	O96017	CHEK2	P53350	PLK1	T205	D203N	203	Missense	proximal	-2	no	12.210	10.968	EPSD;PhosphoSitePlus	COSMIC	10.919	Down-regulation
Other_PLK_PLK1_PLK1_ST	O96017	CHEK2	P53350	PLK1	T205	V200I	200	Missense	distal	-5	no	12.210	12.367	EPSD;PhosphoSitePlus	COSMIC	10.919	Up-regulation
Other_PLK_PLK1_PLK1_ST	O96017	CHEK2	P53350	PLK1	T205	T205I	205	Missense	central	0	yes	12.210	0.000	EPSD;PhosphoSitePlus	COSMIC	10.919	Loss
Other_PLK_PLK1_PLK1_ST	O96017	CHEK2	P53350	PLK1	S210	D203N	203	Missense	distal	-7	no	13.565	13.706	EPSD;PhosphoSitePlus	COSMIC	10.919	Up-regulation
Other_PLK_PLK1_PLK1_ST	O96017	CHEK2	P53350	PLK1	S210	T205I	205	Missense	distal	-5	no	13.565	13.719	EPSD;PhosphoSitePlus	COSMIC	10.919	Up-regulation
Other_PLK_PLK1_PLK1_ST	O96017	CHEK2	P53350	PLK1	S210	L216S	216	Missense	distal	6	no	13.565	13.526	EPSD;PhosphoSitePlus	COSMIC	10.919	Down-regulation
Other_PLK_PLK1_PLK1_ST	O96017	CHEK2	P53350	PLK1	S357	D361Y	361	Missense	distal	4	no	12.026	11.780	EPSD	COSMIC	10.919	Down-regulation
Other_PLK_PLK1_PLK1_ST	O96017	CHEK2	P53350	PLK1	S357	E360Q	360	Missense	distal	3	no	12.026	11.918	EPSD	COSMIC	10.919	Down-regulation
Other_PLK_PLK1_PLK1_ST	O96017	CHEK2	P53350	PLK1	S357	D361E	361	Missense	distal	4	no	12.026	12.012	EPSD	COSMIC	10.919	Down-regulation
Other_PLK_PLK1_PLK1_ST	O96017	CHEK2	P53350	PLK1	S357	S356L	356	Missense	proximal	-1	no	12.026	11.566	EPSD	COSMIC	10.919	Down-regulation
Other_PLK_PLK1_PLK1_ST	O96017	CHEK2	P53350	PLK1	S357	L355P	355	Missense	proximal	-2	no	12.026	12.390	EPSD	COSMIC;CCLE	10.919	Up-regulation
Other_PLK_PLK1_PLK1_ST	O96017	CHEK2	P53350	PLK1	S379	M381I	381	Missense	proximal	2	no	11.848	12.271	EPSD	COSMIC	10.919	Up-regulation
Other_PLK_PLK1_PLK1_ST	O96017	CHEK2	P53350	PLK1	S379	M381V	381	Missense	proximal	2	no	11.848	12.054	EPSD	COSMIC	10.919	Up-regulation
Other_PLK_PLK1_PLK1_ST	O96017	CHEK2	P53350	PLK1	S379	S379C	379	Missense	central	0	yes	11.848	0.000	EPSD	COSMIC	10.919	Loss
Other_PLK_PLK1_PLK1_ST	O96017	CHEK2	P53350	PLK1	S379	S372C	372	Missense	distal	-7	no	11.848	11.230	EPSD	COSMIC	10.919	Down-regulation
Other_PLK_PLK1_PLK1_ST	O96017	CHEK2	P53350	PLK1	T383	M381V	381	Missense	proximal	-2	no	10.595	11.091	EPSD	COSMIC	10.919	Gain
Other_PLK_PLK1_PLK1_ST	O96017	CHEK2	P53350	PLK1	S456	E457K	457	Missense	proximal	1	no	11.045	10.594	EPSD	COSMIC	10.919	Loss
Other_PLK_PLK1_PLK1_ST	O96017	CHEK2	P53350	PLK1	S456	L462I	462	Missense	distal	6	no	11.045	11.007	EPSD	COSMIC	10.919	Down-regulation
Other_PLK_PLK1_PLK1_ST	O96017	CHEK2	P53350	PLK1	S456	S456L	456	Missense	central	0	yes	11.045	0.000	EPSD	COSMIC	10.919	Loss
Other_PLK_PLK1_PLK1_ST	O96017	CHEK2	P53350	PLK1	S456	D461E	461	Missense	distal	5	no	11.045	10.604	EPSD	COSMIC	10.919	Loss
Other_PLK_PLK1_PLK1_ST	O96017	CHEK2	P53350	PLK1	S456	V451L	451	Missense	distal	-5	no	11.045	11.498	EPSD	COSMIC	10.919	Up-regulation
Other_PLK_PLK1_PLK1_ST	O96017	CHEK2	P53350	PLK1	S456	L460I	460	Missense	distal	4	no	11.045	10.466	EPSD	COSMIC	10.919	Loss
Other_PLK_PLK1_PLK1_ST	O96017	CHEK2	P53350	PLK1	S505	Q510H	510	Missense	distal	5	no	11.983	12.128	EPSD	COSMIC	10.919	Up-regulation
Other_PLK_PLK1_PLK1_ST	O60285	NUAK1	P53350	PLK1	S455	P456S	456	Missense	proximal	1	no	11.278	10.157	EPSD	COSMIC	10.919	Loss
Other_PLK_PLK1_PLK1_ST	O60285	NUAK1	P53350	PLK1	S550	P546H	546	Missense	distal	-4	no	15.347	15.203	EPSD	COSMIC	10.919	Down-regulation
Other_PLK_PLK1_PLK1_ST	O60285	NUAK1	P53350	PLK1	S550	G555C	555	Missense	distal	5	no	15.347	15.293	EPSD	COSMIC	10.919	Down-regulation
Other_PLK_PLK1_PLK1_ST	O60285	NUAK1	P53350	PLK1	S570	R563L	563	Missense	distal	-7	no	11.095	11.287	EPSD	COSMIC	10.919	Up-regulation
Other_PLK_PLK1_PLK1_ST	O60285	NUAK1	P53350	PLK1	S570	S576N	576	Missense	distal	6	no	11.095	11.146	EPSD	COSMIC	10.919	Up-regulation
Other_PLK_PLK1_PLK1_ST	O60285	NUAK1	P53350	PLK1	S636	R629W	629	Missense	distal	-7	no	17.165	17.751	EPSD	COSMIC;GDSC	10.919	Up-regulation
Other_PLK_PLK1_PLK1_ST	O60285	NUAK1	P53350	PLK1	S636	F637V	637	Missense	proximal	1	no	17.165	15.685	EPSD	COSMIC;GDSC;CCLE	10.919	Down-regulation
Other_PLK_PLK1_PLK1_ST	O60285	NUAK1	P53350	PLK1	S636	R629Q	629	Missense	distal	-7	no	17.165	17.565	EPSD	COSMIC;CCLE	10.919	Up-regulation
Other_PLK_PLK1_PLK1_ST	Q12888	TP53BP1	P53350	PLK1	S232	S232F	232	Missense	central	0	yes	11.168	0.000	EPSD	COSMIC	10.919	Loss
Other_PLK_PLK1_PLK1_ST	Q12888	TP53BP1	P53350	PLK1	S232	A229S	229	Missense	distal	-3	no	11.168	10.646	EPSD	COSMIC	10.919	Loss
Other_PLK_PLK1_PLK1_ST	Q12888	TP53BP1	P53350	PLK1	S232	P227L	227	Missense	distal	-5	no	11.168	11.569	EPSD	COSMIC	10.919	Up-regulation
Other_PLK_PLK1_PLK1_ST	Q12888	TP53BP1	P53350	PLK1	S354	S359F	359	Missense	distal	5	no	11.812	11.906	EPSD	COSMIC	10.919	Up-regulation
Other_PLK_PLK1_PLK1_ST	Q12888	TP53BP1	P53350	PLK1	S354	S356F	356	Missense	proximal	2	no	11.812	11.261	EPSD	COSMIC	10.919	Down-regulation
Other_PLK_PLK1_PLK1_ST	Q12888	TP53BP1	P53350	PLK1	S360	S359F	359	Missense	proximal	-1	no	14.922	14.383	EPSD	COSMIC	10.919	Down-regulation
Other_PLK_PLK1_PLK1_ST	Q12888	TP53BP1	P53350	PLK1	S360	V363F	363	Missense	distal	3	no	14.922	14.830	EPSD	COSMIC	10.919	Down-regulation
Other_PLK_PLK1_PLK1_ST	Q12888	TP53BP1	P53350	PLK1	S360	S356F	356	Missense	distal	-4	no	14.922	14.604	EPSD	COSMIC	10.919	Down-regulation
Other_PLK_PLK1_PLK1_ST	Q12888	TP53BP1	P53350	PLK1	S366	S359F	359	Missense	distal	-7	no	11.285	10.828	EPSD	COSMIC	10.919	Loss
Other_PLK_PLK1_PLK1_ST	Q12888	TP53BP1	P53350	PLK1	S366	V363F	363	Missense	distal	-3	no	11.285	10.532	EPSD	COSMIC	10.919	Loss
Other_PLK_PLK1_PLK1_ST	Q12888	TP53BP1	P53350	PLK1	S366	D368N	368	Missense	proximal	2	no	11.285	11.500	EPSD	COSMIC	10.919	Up-regulation
Other_PLK_PLK1_PLK1_ST	Q12888	TP53BP1	P53350	PLK1	S395	E400K	400	Missense	distal	5	no	13.544	13.555	EPSD	COSMIC	10.919	Up-regulation
Other_PLK_PLK1_PLK1_ST	Q12888	TP53BP1	P53350	PLK1	S395	M392I	392	Missense	distal	-3	no	13.544	13.691	EPSD	COSMIC	10.919	Up-regulation
Other_PLK_PLK1_PLK1_ST	Q12888	TP53BP1	P53350	PLK1	S484	M480I	480	Missense	distal	-4	no	11.231	11.540	EPSD	COSMIC;CCLE	10.919	Up-regulation
Other_PLK_PLK1_PLK1_ST	Q12888	TP53BP1	P53350	PLK1	S484	D479N	479	Missense	distal	-5	no	11.231	10.934	EPSD	COSMIC	10.919	Down-regulation
Other_PLK_PLK1_PLK1_ST	Q12888	TP53BP1	P53350	PLK1	S484	S484F	484	Missense	central	0	yes	11.231	0.000	EPSD	COSMIC	10.919	Loss
Other_PLK_PLK1_PLK1_ST	Q12888	TP53BP1	P53350	PLK1	S523	T519A	519	Missense	distal	-4	no	12.026	12.428	EPSD	COSMIC	10.919	Up-regulation
Other_PLK_PLK1_PLK1_ST	Q12888	TP53BP1	P53350	PLK1	S530	R535I	535	Missense	distal	5	no	11.108	11.061	EPSD	COSMIC	10.919	Down-regulation
Other_PLK_PLK1_PLK1_ST	Q12888	TP53BP1	P53350	PLK1	S530	R535K	535	Missense	distal	5	no	11.108	10.483	EPSD	COSMIC	10.919	Loss
Other_PLK_PLK1_PLK1_ST	Q12888	TP53BP1	P53350	PLK1	T543	T548A	548	Missense	distal	5	no	12.733	13.905	EPSD	COSMIC	10.919	Up-regulation
Other_PLK_PLK1_PLK1_ST	Q12888	TP53BP1	P53350	PLK1	S552	T548A	548	Missense	distal	-4	no	12.408	12.810	EPSD	COSMIC	10.919	Up-regulation
Other_PLK_PLK1_PLK1_ST	Q12888	TP53BP1	P53350	PLK1	S566	P561S	561	Missense	distal	-5	no	12.265	12.002	EPSD	COSMIC	10.919	Down-regulation
Other_PLK_PLK1_PLK1_ST	Q12888	TP53BP1	P53350	PLK1	T620	D622N	622	Missense	proximal	2	no	10.895	11.109	EPSD	COSMIC	10.919	Gain
Other_PLK_PLK1_PLK1_ST	Q12888	TP53BP1	P53350	PLK1	S660	G658A	658	Missense	proximal	-2	no	10.866	11.616	EPSD	COSMIC	10.919	Gain
Other_PLK_PLK1_PLK1_ST	Q12888	TP53BP1	P53350	PLK1	S765	R767I	767	Missense	proximal	2	no	10.672	11.821	EPSD	COSMIC	10.919	Gain
Other_PLK_PLK1_PLK1_ST	Q12888	TP53BP1	P53350	PLK1	S809	E811G	811	Missense	proximal	2	no	13.717	12.728	EPSD	COSMIC	10.919	Down-regulation
Other_PLK_PLK1_PLK1_ST	Q12888	TP53BP1	P53350	PLK1	S809	Y812C	812	Missense	distal	3	no	13.717	13.833	EPSD	COSMIC	10.919	Up-regulation
Other_PLK_PLK1_PLK1_ST	Q12888	TP53BP1	P53350	PLK1	S894	S899R	899	Missense	distal	5	no	11.579	11.923	EPSD	COSMIC	10.919	Up-regulation
Other_PLK_PLK1_PLK1_ST	Q12888	TP53BP1	P53350	PLK1	S894	S888A	888	Missense	distal	-6	no	11.579	11.543	EPSD	COSMIC	10.919	Down-regulation
Other_PLK_PLK1_PLK1_ST	Q12888	TP53BP1	P53350	PLK1	S894	S894R	894	Missense	central	0	yes	11.579	0.000	EPSD	COSMIC	10.919	Loss
Other_PLK_PLK1_PLK1_ST	Q12888	TP53BP1	P53350	PLK1	S1002	S1002C	1002	Missense	central	0	yes	13.048	0.000	EPSD	COSMIC	10.919	Loss
Other_PLK_PLK1_PLK1_ST	Q12888	TP53BP1	P53350	PLK1	S1002	N1006Y	1006	Missense	distal	4	no	13.048	13.041	EPSD	COSMIC	10.919	Down-regulation
Other_PLK_PLK1_PLK1_ST	Q12888	TP53BP1	P53350	PLK1	T1082	P1089L	1089	Missense	distal	7	no	11.631	11.603	EPSD	COSMIC	10.919	Down-regulation
Other_PLK_PLK1_PLK1_ST	Q12888	TP53BP1	P53350	PLK1	S1094	P1089L	1089	Missense	distal	-5	no	12.290	12.692	EPSD	COSMIC	10.919	Up-regulation
Other_PLK_PLK1_PLK1_ST	Q12888	TP53BP1	P53350	PLK1	S1094	S1094N	1094	Missense	central	0	yes	12.290	0.000	EPSD	COSMIC	10.919	Loss
Other_PLK_PLK1_PLK1_ST	Q12888	TP53BP1	P53350	PLK1	S1094	S1094C	1094	Missense	central	0	yes	12.290	0.000	EPSD	COSMIC	10.919	Loss
Other_PLK_PLK1_PLK1_ST	Q12888	TP53BP1	P53350	PLK1	S1094	S1101F	1101	Missense	distal	7	no	12.290	12.360	EPSD	COSMIC	10.919	Up-regulation
Other_PLK_PLK1_PLK1_ST	Q12888	TP53BP1	P53350	PLK1	T1195	V1196I	1196	Missense	proximal	1	no	11.765	11.956	EPSD	COSMIC	10.919	Up-regulation
Other_PLK_PLK1_PLK1_ST	Q12888	TP53BP1	P53350	PLK1	T1195	T1198I	1198	Missense	distal	3	no	11.765	11.932	EPSD	COSMIC	10.919	Up-regulation
Other_PLK_PLK1_PLK1_ST	Q12888	TP53BP1	P53350	PLK1	T1273	E1271Q	1271	Missense	proximal	-2	no	11.876	9.217	EPSD	COSMIC	10.919	Loss
Other_PLK_PLK1_PLK1_ST	Q12888	TP53BP1	P53350	PLK1	T1273	P1276L	1276	Missense	distal	3	no	11.876	11.708	EPSD	COSMIC	10.919	Down-regulation
Other_PLK_PLK1_PLK1_ST	Q12888	TP53BP1	P53350	PLK1	T1273	E1266Q	1266	Missense	distal	-7	no	11.876	11.840	EPSD	COSMIC	10.919	Down-regulation
Other_PLK_PLK1_PLK1_ST	Q12888	TP53BP1	P53350	PLK1	T1273	E1272K	1272	Missense	proximal	-1	no	11.876	11.305	EPSD	COSMIC	10.919	Down-regulation
Other_PLK_PLK1_PLK1_ST	Q12888	TP53BP1	P53350	PLK1	S1288	T1285S	1285	Missense	distal	-3	no	14.100	13.724	EPSD	COSMIC	10.919	Down-regulation
Other_PLK_PLK1_PLK1_ST	Q12888	TP53BP1	P53350	PLK1	S1288	Q1291E	1291	Missense	distal	3	no	14.100	14.208	EPSD	COSMIC	10.919	Up-regulation
Other_PLK_PLK1_PLK1_ST	Q12888	TP53BP1	P53350	PLK1	S1303	S1307F	1307	Missense	distal	4	no	11.475	10.661	EPSD	COSMIC	10.919	Loss
Other_PLK_PLK1_PLK1_ST	Q12888	TP53BP1	P53350	PLK1	S1303	D1298N	1298	Missense	distal	-5	no	11.475	11.178	EPSD	COSMIC	10.919	Down-regulation
Other_PLK_PLK1_PLK1_ST	Q12888	TP53BP1	P53350	PLK1	S1311	S1307F	1307	Missense	distal	-4	no	12.940	12.622	EPSD	COSMIC	10.919	Down-regulation
Other_PLK_PLK1_PLK1_ST	Q12888	TP53BP1	P53350	PLK1	S1311	R1314H	1314	Missense	distal	3	no	12.940	13.071	EPSD	COSMIC	10.919	Up-regulation
Other_PLK_PLK1_PLK1_ST	Q12888	TP53BP1	P53350	PLK1	S1317	R1314H	1314	Missense	distal	-3	no	11.305	10.633	EPSD	COSMIC	10.919	Loss
Other_PLK_PLK1_PLK1_ST	Q12888	TP53BP1	P53350	PLK1	S1435	S1435F	1435	Missense	central	0	yes	14.652	0.000	EPSD	COSMIC	10.919	Loss
Other_PLK_PLK1_PLK1_ST	Q12888	TP53BP1	P53350	PLK1	S1435	R1438H	1438	Missense	distal	3	no	14.652	14.783	EPSD	COSMIC	10.919	Up-regulation
Other_PLK_PLK1_PLK1_ST	Q12888	TP53BP1	P53350	PLK1	S1462	R1458H	1458	Missense	distal	-4	no	12.059	12.360	EPSD	COSMIC	10.919	Up-regulation
Other_PLK_PLK1_PLK1_ST	Q12888	TP53BP1	P53350	PLK1	S1571	I1572S	1572	Missense	proximal	1	no	13.488	11.729	EPSD	COSMIC	10.919	Down-regulation
Other_PLK_PLK1_PLK1_ST	Q12888	TP53BP1	P53350	PLK1	S1571	G1566V	1566	Missense	distal	-5	no	13.488	13.301	EPSD	COSMIC	10.919	Down-regulation
Other_PLK_PLK1_PLK1_ST	Q12888	TP53BP1	P53350	PLK1	S1618	A1614V	1614	Missense	distal	-4	no	12.606	12.466	PhosphoSitePlus	COSMIC;CCLE	10.919	Down-regulation
Other_PLK_PLK1_PLK1_ST	Q12888	TP53BP1	P53350	PLK1	S1618	G1625R	1625	Missense	distal	7	no	12.606	12.623	PhosphoSitePlus	COSMIC	10.919	Up-regulation
Other_PLK_PLK1_PLK1_ST	Q12888	TP53BP1	P53350	PLK1	S1631	S1635P	1635	Missense	distal	4	no	11.235	10.913	EPSD	COSMIC	10.919	Loss
Other_PLK_PLK1_PLK1_ST	Q12888	TP53BP1	P53350	PLK1	S1631	G1625R	1625	Missense	distal	-6	no	11.235	11.333	EPSD	COSMIC	10.919	Up-regulation
Other_PLK_PLK1_PLK1_ST	Q12888	TP53BP1	P53350	PLK1	S1631	S1635F	1635	Missense	distal	4	no	11.235	10.421	EPSD	COSMIC	10.919	Loss
Other_PLK_PLK1_PLK1_ST	Q12888	TP53BP1	P53350	PLK1	S1634	S1635F	1635	Missense	proximal	1	no	8.531	11.580	EPSD	COSMIC	10.919	Gain
Other_PLK_PLK1_PLK1_ST	Q12888	TP53BP1	P53350	PLK1	S1656	P1657S	1657	Missense	proximal	1	no	11.479	10.358	EPSD	COSMIC	10.919	Loss
Other_PLK_PLK1_PLK1_ST	Q12888	TP53BP1	P53350	PLK1	S1656	A1659V	1659	Missense	distal	3	no	11.479	11.807	EPSD	COSMIC	10.919	Up-regulation
Other_PLK_PLK1_PLK1_ST	Q12888	TP53BP1	P53350	PLK1	S1656	R1651Q	1651	Missense	distal	-5	no	11.479	10.740	EPSD	COSMIC	10.919	Loss
Other_PLK_PLK1_PLK1_ST	Q12888	TP53BP1	P53350	PLK1	S1656	M1661T	1661	Missense	distal	5	no	11.479	10.778	EPSD	COSMIC	10.919	Loss
Other_PLK_PLK1_PLK1_ST	Q12888	TP53BP1	P53350	PLK1	T1709	S1713I	1713	Missense	distal	4	no	11.663	10.472	EPSD	COSMIC	10.919	Loss
Other_PLK_PLK1_PLK1_ST	Q12888	TP53BP1	P53350	PLK1	T1709	A1714S	1714	Missense	distal	5	no	11.663	11.097	EPSD	COSMIC	10.919	Down-regulation
Other_PLK_PLK1_PLK1_ST	Q12888	TP53BP1	P53350	PLK1	S1929	P1927L	1927	Missense	proximal	-2	no	11.665	11.301	EPSD	COSMIC	10.919	Down-regulation
Other_PLK_PLK1_PLK1_ST	Q12888	TP53BP1	P53350	PLK1	S1929	D1923E	1923	Missense	distal	-6	no	11.665	11.868	EPSD	COSMIC	10.919	Up-regulation
Other_PLK_PLK1_PLK1_ST	Q12888	TP53BP1	P53350	PLK1	S1929	D1923N	1923	Missense	distal	-6	no	11.665	11.552	EPSD	COSMIC;CCLE	10.919	Down-regulation
Other_PLK_PLK1_PLK1_ST	Q12888	TP53BP1	P53350	PLK1	S1929	V1930G	1930	Missense	proximal	1	no	11.665	11.034	EPSD	COSMIC	10.919	Down-regulation
Other_PLK_PLK1_PLK1_ST	Q12888	TP53BP1	P53350	PLK1	S1929	S1925L	1925	Missense	distal	-4	no	11.665	11.471	EPSD	COSMIC	10.919	Down-regulation
Other_PLK_PLK1_PLK1_ST	Q12888	TP53BP1	P53350	PLK1	S1929	C1926F	1926	Missense	distal	-3	no	11.665	10.999	EPSD	COSMIC	10.919	Down-regulation
Other_PLK_PLK1_PLK1_ST	Q12888	TP53BP1	P53350	PLK1	S1929	P1924L	1924	Missense	distal	-5	no	11.665	12.066	EPSD	COSMIC	10.919	Up-regulation
Other_PLK_PLK1_PLK1_ST	Q12888	TP53BP1	P53350	PLK1	S1929	T1922K	1922	Missense	distal	-7	no	11.665	11.309	EPSD	COSMIC	10.919	Down-regulation
Other_PLK_PLK1_PLK1_ST	P08670	VIM	P53350	PLK1	S29	R36H	36	Missense	distal	7	no	12.166	12.137	EPSD	COSMIC	10.919	Down-regulation
Other_PLK_PLK1_PLK1_ST	P08670	VIM	P53350	PLK1	S29	S27R	27	Missense	proximal	-2	no	12.166	11.940	EPSD	COSMIC	10.919	Down-regulation
Other_PLK_PLK1_PLK1_ST	P08670	VIM	P53350	PLK1	S29	S34P	34	Missense	distal	5	no	12.166	12.553	EPSD	COSMIC	10.919	Up-regulation
Other_PLK_PLK1_PLK1_ST	P08670	VIM	P53350	PLK1	S83	V77L	77	Missense	distal	-6	no	12.080	12.021	PhosphoSitePlus;EPSD	COSMIC	10.919	Down-regulation
Other_PLK_PLK1_PLK1_ST	P08670	VIM	P53350	PLK1	S87	A91T	91	Missense	distal	4	no	14.167	14.174	EPSD	COSMIC	10.919	Up-regulation
Other_PLK_PLK1_PLK1_ST	P08670	VIM	P53350	PLK1	S293	Y291C	291	Missense	proximal	-2	no	11.059	7.549	EPSD	COSMIC	10.919	Loss
Other_PLK_PLK1_PLK1_ST	P08670	VIM	P53350	PLK1	S299	R304W	304	Missense	distal	5	no	13.360	13.102	EPSD	COSMIC	10.919	Down-regulation
Other_PLK_PLK1_PLK1_ST	P08670	VIM	P53350	PLK1	S430	V434G	434	Missense	distal	4	no	10.922	11.298	EPSD	COSMIC	10.919	Up-regulation
Other_PLK_PLK1_PLK1_ST	P08670	VIM	P53350	PLK1	S430	E425K	425	Missense	distal	-5	no	10.922	11.165	EPSD	COSMIC	10.919	Up-regulation
Other_PLK_PLK1_PLK1_ST	P08670	VIM	P53350	PLK1	S430	L433M	433	Missense	distal	3	no	10.922	10.779	EPSD	COSMIC	10.919	Loss
Other_PLK_PLK1_PLK1_ST	P08670	VIM	P53350	PLK1	S459	Q453E	453	Missense	distal	-6	no	11.973	12.092	EPSD	COSMIC;GDSC;CCLE	10.919	Up-regulation
Other_PLK_PLK1_PLK1_ST	P08670	VIM	P53350	PLK1	S459	I455V	455	Missense	distal	-4	no	11.973	11.839	EPSD	COSMIC	10.919	Down-regulation
Other_PLK_PLK1_PLK1_ST	O95425	SVIL	P53350	PLK1	S66	S66A	66	Missense	central	0	yes	13.619	0.000	EPSD	COSMIC	10.919	Loss
Other_PLK_PLK1_PLK1_ST	O95425	SVIL	P53350	PLK1	S193	S194F	194	Missense	proximal	1	no	9.758	12.806	EPSD	COSMIC	10.919	Gain
Other_PLK_PLK1_PLK1_ST	O95425	SVIL	P53350	PLK1	S227	T229N	229	Missense	proximal	2	no	10.511	11.365	EPSD	COSMIC	10.919	Gain
Other_PLK_PLK1_PLK1_ST	O95425	SVIL	P53350	PLK1	S231	T229N	229	Missense	proximal	-2	no	9.155	11.103	EPSD	COSMIC	10.919	Gain
Other_PLK_PLK1_PLK1_ST	O95425	SVIL	P53350	PLK1	S238	S237F	237	Missense	proximal	-1	no	15.559	15.020	PhosphoSitePlus	COSMIC	10.919	Down-regulation
Other_PLK_PLK1_PLK1_ST	O95425	SVIL	P53350	PLK1	S261	R260L	260	Missense	proximal	-1	no	12.185	12.662	EPSD	COSMIC	10.919	Up-regulation
Other_PLK_PLK1_PLK1_ST	O95425	SVIL	P53350	PLK1	S315	K312N	312	Missense	distal	-3	no	13.327	13.145	EPSD	COSMIC	10.919	Down-regulation
Other_PLK_PLK1_PLK1_ST	O95425	SVIL	P53350	PLK1	S315	K312T	312	Missense	distal	-3	no	13.327	13.332	EPSD	COSMIC	10.919	Up-regulation
Other_PLK_PLK1_PLK1_ST	O95425	SVIL	P53350	PLK1	S341	S341L	341	Missense	central	0	yes	13.673	0.000	EPSD	COSMIC	10.919	Loss
Other_PLK_PLK1_PLK1_ST	O95425	SVIL	P53350	PLK1	S341	E345Q	345	Missense	distal	4	no	13.673	13.270	EPSD	COSMIC	10.919	Down-regulation
Other_PLK_PLK1_PLK1_ST	O95425	SVIL	P53350	PLK1	S341	S347L	347	Missense	distal	6	no	13.673	13.713	EPSD	COSMIC;GDSC;CCLE	10.919	Up-regulation
Other_PLK_PLK1_PLK1_ST	O95425	SVIL	P53350	PLK1	S341	S341P	341	Missense	central	0	yes	13.673	0.000	EPSD	COSMIC	10.919	Loss
Other_PLK_PLK1_PLK1_ST	O95425	SVIL	P53350	PLK1	S538	N534S	534	Missense	distal	-4	no	11.156	11.290	EPSD	COSMIC	10.919	Up-regulation
Other_PLK_PLK1_PLK1_ST	O95425	SVIL	P53350	PLK1	S549	P555A	555	Missense	distal	6	no	11.073	11.212	EPSD	COSMIC	10.919	Up-regulation
Other_PLK_PLK1_PLK1_ST	O95425	SVIL	P53350	PLK1	S644	R637W	637	Missense	distal	-7	no	11.462	12.048	EPSD	COSMIC	10.919	Up-regulation
Other_PLK_PLK1_PLK1_ST	O95425	SVIL	P53350	PLK1	S644	R641C	641	Missense	distal	-3	no	11.462	10.666	EPSD	COSMIC;GDSC	10.919	Loss
Other_PLK_PLK1_PLK1_ST	O95425	SVIL	P53350	PLK1	S734	T736P	736	Missense	proximal	2	no	14.484	13.649	EPSD	COSMIC	10.919	Down-regulation
Other_PLK_PLK1_PLK1_ST	O95425	SVIL	P53350	PLK1	S811	A816V	816	Missense	distal	5	no	13.877	13.139	EPSD	COSMIC	10.919	Down-regulation
Other_PLK_PLK1_PLK1_ST	O95425	SVIL	P53350	PLK1	T852	V855I	855	Missense	distal	3	no	11.402	11.279	EPSD	COSMIC	10.919	Down-regulation
Other_PLK_PLK1_PLK1_ST	O95425	SVIL	P53350	PLK1	T852	A848V	848	Missense	distal	-4	no	11.402	11.262	EPSD	COSMIC	10.919	Down-regulation
Other_PLK_PLK1_PLK1_ST	O95425	SVIL	P53350	PLK1	S884	T885M	885	Missense	proximal	1	no	9.865	11.997	EPSD	COSMIC	10.919	Gain
Other_PLK_PLK1_PLK1_ST	O95425	SVIL	P53350	PLK1	S905	S912F	912	Missense	distal	7	no	11.090	11.159	EPSD	COSMIC	10.919	Up-regulation
Other_PLK_PLK1_PLK1_ST	O95425	SVIL	P53350	PLK1	S918	S918F	918	Missense	central	0	yes	13.078	0.000	EPSD	COSMIC	10.919	Loss
Other_PLK_PLK1_PLK1_ST	O95425	SVIL	P53350	PLK1	S918	S912F	912	Missense	distal	-6	no	13.078	12.561	EPSD	COSMIC	10.919	Down-regulation
Other_PLK_PLK1_PLK1_ST	O95425	SVIL	P53350	PLK1	S920	S918F	918	Missense	proximal	-2	no	11.777	10.219	EPSD	COSMIC	10.919	Loss
Other_PLK_PLK1_PLK1_ST	O95425	SVIL	P53350	PLK1	S938	S938I	938	Missense	central	0	yes	11.444	0.000	EPSD	COSMIC	10.919	Loss
Other_PLK_PLK1_PLK1_ST	O95425	SVIL	P53350	PLK1	S968	A972V	972	Missense	distal	4	no	14.941	14.677	EPSD	COSMIC	10.919	Down-regulation
Other_PLK_PLK1_PLK1_ST	O95425	SVIL	P53350	PLK1	S968	S961C	961	Missense	distal	-7	no	14.941	14.323	EPSD	COSMIC	10.919	Down-regulation
Other_PLK_PLK1_PLK1_ST	O95425	SVIL	P53350	PLK1	S968	A972T	972	Missense	distal	4	no	14.941	14.947	EPSD	COSMIC	10.919	Up-regulation
Other_PLK_PLK1_PLK1_ST	O95425	SVIL	P53350	PLK1	S968	E970K	970	Missense	proximal	2	no	14.941	14.772	EPSD	COSMIC	10.919	Down-regulation
Other_PLK_PLK1_PLK1_ST	O95425	SVIL	P53350	PLK1	S968	E970Q	970	Missense	proximal	2	no	14.941	15.130	EPSD	COSMIC	10.919	Up-regulation
Other_PLK_PLK1_PLK1_ST	O95425	SVIL	P53350	PLK1	S975	P977L	977	Missense	proximal	2	no	9.604	11.152	EPSD	COSMIC	10.919	Gain
Other_PLK_PLK1_PLK1_ST	O95425	SVIL	P53350	PLK1	T1230	P1235A	1235	Missense	distal	5	no	11.758	11.938	EPSD	COSMIC	10.919	Up-regulation
Other_PLK_PLK1_PLK1_ST	O95425	SVIL	P53350	PLK1	T1230	A1224V	1224	Missense	distal	-6	no	11.758	11.519	EPSD	COSMIC	10.919	Down-regulation
Other_PLK_PLK1_PLK1_ST	O95425	SVIL	P53350	PLK1	T1230	A1228D	1228	Missense	proximal	-2	no	11.758	14.330	EPSD	COSMIC	10.919	Up-regulation
Other_PLK_PLK1_PLK1_ST	O95425	SVIL	P53350	PLK1	S1314	M1319I	1319	Missense	distal	5	no	10.894	11.095	EPSD	COSMIC	10.919	Gain
Other_PLK_PLK1_PLK1_ST	O95425	SVIL	P53350	PLK1	S1314	V1315M	1315	Missense	proximal	1	no	10.894	12.050	EPSD	COSMIC;GDSC;CCLE	10.919	Gain
Other_PLK_PLK1_PLK1_ST	O95425	SVIL	P53350	PLK1	S1419	E1416G	1416	Missense	distal	-3	no	10.159	11.100	EPSD	COSMIC	10.919	Gain
Other_PLK_PLK1_PLK1_ST	O95425	SVIL	P53350	PLK1	S1422	V1421I	1421	Missense	proximal	-1	no	10.503	11.477	EPSD	COSMIC	10.919	Gain
Other_PLK_PLK1_PLK1_ST	O95425	SVIL	P53350	PLK1	S1911	L1906P	1906	Missense	distal	-5	no	11.912	11.510	EPSD	COSMIC	10.919	Down-regulation
Other_PLK_PLK1_PLK1_ST	O95425	SVIL	P53350	PLK1	S1911	S1905G	1905	Missense	distal	-6	no	11.912	11.366	EPSD	COSMIC	10.919	Down-regulation
Other_PLK_PLK1_PLK1_ST	Q9UJX2	CDC23	P53350	PLK1	S21	S24R	24	Missense	distal	3	no	11.022	10.898	EPSD	COSMIC	10.919	Loss
Other_PLK_PLK1_PLK1_ST	Q9UJX2	CDC23	P53350	PLK1	S27	S24R	24	Missense	distal	-3	no	14.419	15.251	EPSD	COSMIC	10.919	Up-regulation
Other_PLK_PLK1_PLK1_ST	Q9UJX2	CDC23	P53350	PLK1	T134	T134I	134	Missense	central	0	yes	12.873	0.000	EPSD	COSMIC	10.919	Loss
Other_PLK_PLK1_PLK1_ST	Q9UJX2	CDC23	P53350	PLK1	T302	R296S	296	Missense	distal	-6	no	11.238	11.685	EPSD	COSMIC	10.919	Up-regulation
Other_PLK_PLK1_PLK1_ST	Q9UJX2	CDC23	P53350	PLK1	T562	P563L	563	Missense	proximal	1	no	10.766	11.611	PhosphoSitePlus;EPSD	COSMIC	10.919	Gain
Other_PLK_PLK1_PLK1_ST	Q9UJX2	CDC23	P53350	PLK1	T565	F571L	571	Missense	distal	6	no	11.542	12.157	EPSD;PhosphoSitePlus	COSMIC	10.919	Up-regulation
Other_PLK_PLK1_PLK1_ST	Q9UJX2	CDC23	P53350	PLK1	T565	F572V	572	Missense	distal	7	no	11.542	11.520	EPSD;PhosphoSitePlus	COSMIC	10.919	Down-regulation
Other_PLK_PLK1_PLK1_ST	Q9UJX2	CDC23	P53350	PLK1	T565	P563L	563	Missense	proximal	-2	no	11.542	11.178	EPSD;PhosphoSitePlus	COSMIC	10.919	Down-regulation
Other_PLK_PLK1_PLK1_ST	P30291	WEE1	P53350	PLK1	S53	G50S	50	Missense	distal	-3	no	13.900	13.127	PhosphoSitePlus	COSMIC	10.919	Down-regulation
Other_PLK_PLK1_PLK1_ST	P30291	WEE1	P53350	PLK1	S53	D52G	52	Missense	proximal	-1	no	13.900	11.310	PhosphoSitePlus	COSMIC	10.919	Down-regulation
Other_PLK_PLK1_PLK1_ST	P30291	WEE1	P53350	PLK1	S53	Q56E	56	Missense	distal	3	no	13.900	14.008	PhosphoSitePlus	COSMIC	10.919	Up-regulation
Other_PLK_PLK1_PLK1_ST	P30291	WEE1	P53350	PLK1	S123	A129T	129	Missense	distal	6	no	13.184	13.177	EPSD	COSMIC	10.919	Down-regulation
Other_PLK_PLK1_PLK1_ST	P30291	WEE1	P53350	PLK1	S204	K197T	197	Missense	distal	-7	no	12.170	12.526	EPSD	COSMIC	10.919	Up-regulation
Other_PLK_PLK1_PLK1_ST	P30291	WEE1	P53350	PLK1	S242	L244F	244	Missense	proximal	2	no	11.613	10.990	EPSD	COSMIC	10.919	Down-regulation
Other_PLK_PLK1_PLK1_ST	P30291	WEE1	P53350	PLK1	S270	D271G	271	Missense	proximal	1	no	12.246	12.248	EPSD	COSMIC	10.919	Up-regulation
Other_PLK_PLK1_PLK1_ST	P30291	WEE1	P53350	PLK1	S289	K292N	292	Missense	distal	3	no	12.095	12.167	EPSD	COSMIC	10.919	Up-regulation
Other_PLK_PLK1_PLK1_ST	P30291	WEE1	P53350	PLK1	S640	R639H	639	Missense	proximal	-1	no	13.160	14.157	EPSD	COSMIC	10.919	Up-regulation
Other_PLK_PLK1_PLK1_ST	O60341	KDM1A	P53350	PLK1	T19	A12S	12	Missense	distal	-7	no	11.315	11.668	EPSD	COSMIC	10.919	Up-regulation
Other_PLK_PLK1_PLK1_ST	O60341	KDM1A	P53350	PLK1	T19	A12V	12	Missense	distal	-7	no	11.315	11.372	EPSD	COSMIC	10.919	Up-regulation
Other_PLK_PLK1_PLK1_ST	O60341	KDM1A	P53350	PLK1	T19	G20R	20	Missense	proximal	1	no	11.315	9.213	EPSD	COSMIC	10.919	Loss
Other_PLK_PLK1_PLK1_ST	O60341	KDM1A	P53350	PLK1	S126	N129T	129	Missense	distal	3	no	16.215	16.033	PhosphoSitePlus	COSMIC	10.919	Down-regulation
Other_PLK_PLK1_PLK1_ST	O60341	KDM1A	P53350	PLK1	S131	E138K	138	Missense	distal	7	no	10.958	11.031	EPSD	COSMIC	10.919	Up-regulation
Other_PLK_PLK1_PLK1_ST	O60341	KDM1A	P53350	PLK1	S131	N129T	129	Missense	proximal	-2	no	10.958	9.010	EPSD	COSMIC	10.919	Loss
Other_PLK_PLK1_PLK1_ST	O60341	KDM1A	P53350	PLK1	S172	E175D	175	Missense	distal	3	no	12.204	12.270	EPSD	COSMIC	10.919	Up-regulation
Other_PLK_PLK1_PLK1_ST	O60341	KDM1A	P53350	PLK1	T305	L307M	307	Missense	proximal	2	no	12.661	12.587	EPSD	COSMIC	10.919	Down-regulation
Other_PLK_PLK1_PLK1_ST	O60341	KDM1A	P53350	PLK1	T305	A309S	309	Missense	distal	4	no	12.661	12.860	EPSD	COSMIC	10.919	Up-regulation
Other_PLK_PLK1_PLK1_ST	O60341	KDM1A	P53350	PLK1	T305	R312C	312	Missense	distal	7	no	12.661	12.714	EPSD	COSMIC;GDSC;CCLE	10.919	Up-regulation
Other_PLK_PLK1_PLK1_ST	O60341	KDM1A	P53350	PLK1	T305	F300C	300	Missense	distal	-5	no	12.661	12.940	EPSD	COSMIC	10.919	Up-regulation
Other_PLK_PLK1_PLK1_ST	O60341	KDM1A	P53350	PLK1	T305	Q298R	298	Missense	distal	-7	no	12.661	12.261	EPSD	COSMIC	10.919	Down-regulation
Other_PLK_PLK1_PLK1_ST	O60341	KDM1A	P53350	PLK1	T305	A309T	309	Missense	distal	4	no	12.661	12.667	EPSD	COSMIC	10.919	Up-regulation
Other_PLK_PLK1_PLK1_ST	O60341	KDM1A	P53350	PLK1	T305	E308K	308	Missense	distal	3	no	12.661	12.455	EPSD	COSMIC	10.919	Down-regulation
Other_PLK_PLK1_PLK1_ST	P62826	RAN	P53350	PLK1	S135	A133V	133	Missense	proximal	-2	no	11.520	11.480	PhosphoSitePlus	COSMIC	10.919	Down-regulation
Other_PLK_PLK1_PLK1_ST	P62826	RAN	P53350	PLK1	S135	K132N	132	Missense	distal	-3	no	11.520	11.339	PhosphoSitePlus	COSMIC	10.919	Down-regulation
Other_PLK_PLK1_PLK1_ST	Q9Y2Z0	SUGT1	P53350	PLK1	S331	A327D	327	Missense	distal	-4	no	14.665	14.432	PhosphoSitePlus	COSMIC;GDSC;CCLE	10.919	Down-regulation
Other_PLK_PLK1_PLK1_ST	Q9Y2Z0	SUGT1	P53350	PLK1	S331	R326H	326	Missense	distal	-5	no	14.665	13.862	PhosphoSitePlus	COSMIC	10.919	Down-regulation
Other_PLK_PLK1_PLK1_ST	Q9Y2Z0	SUGT1	P53350	PLK1	S331	N329S	329	Missense	proximal	-2	no	14.665	13.255	PhosphoSitePlus	COSMIC	10.919	Down-regulation
Other_PLK_PLK1_PLK1_ST	Q9Y2Z0	SUGT1	P53350	PLK1	S345	V352F	352	Missense	distal	7	no	12.900	12.922	EPSD	COSMIC	10.919	Up-regulation
Other_PLK_PLK1_PLK1_ST	O15350	TP73	P53350	PLK1	T27	D30A	30	Missense	distal	3	no	13.888	13.466	PhosphoSitePlus	COSMIC	10.919	Down-regulation
Other_PLK_PLK1_PLK1_ST	O15350	TP73	P53350	PLK1	T27	S26L	26	Missense	proximal	-1	no	13.888	13.428	PhosphoSitePlus	COSMIC	10.919	Down-regulation
Other_PLK_PLK1_PLK1_ST	O15350	TP73	P53350	PLK1	S47	S48L	48	Missense	proximal	1	no	10.228	12.195	EPSD	COSMIC	10.919	Gain
Other_PLK_PLK1_PLK1_ST	O15350	TP73	P53350	PLK1	S48	D50Y	50	Missense	proximal	2	no	14.479	14.113	EPSD	COSMIC;GDSC;CCLE	10.919	Down-regulation
Other_PLK_PLK1_PLK1_ST	O15350	TP73	P53350	PLK1	S48	E55K	55	Missense	distal	7	no	14.479	14.552	EPSD	COSMIC	10.919	Up-regulation
Other_PLK_PLK1_PLK1_ST	O15350	TP73	P53350	PLK1	S48	S48L	48	Missense	central	0	yes	14.479	0.000	EPSD	COSMIC	10.919	Loss
Other_PLK_PLK1_PLK1_ST	O15350	TP73	P53350	PLK1	T167	Q162R	162	Missense	distal	-5	no	11.790	12.530	EPSD	COSMIC	10.919	Up-regulation
Other_PLK_PLK1_PLK1_ST	O15350	TP73	P53350	PLK1	T167	A174G	174	Missense	distal	7	no	11.790	11.764	EPSD	COSMIC	10.919	Down-regulation
Other_PLK_PLK1_PLK1_ST	O15350	TP73	P53350	PLK1	T167	S166F	166	Missense	proximal	-1	no	11.790	11.251	EPSD	COSMIC	10.919	Down-regulation
Other_PLK_PLK1_PLK1_ST	O15350	TP73	P53350	PLK1	T167	P171L	171	Missense	distal	4	no	11.790	11.500	EPSD	COSMIC	10.919	Down-regulation
Other_PLK_PLK1_PLK1_ST	Q9Y265	RUVBL1	P53350	PLK1	S19	T12A	12	Missense	distal	-7	no	11.064	10.719	EPSD	COSMIC	10.919	Loss
Other_PLK_PLK1_PLK1_ST	Q9Y265	RUVBL1	P53350	PLK1	S19	R14C	14	Missense	distal	-5	no	11.064	10.398	EPSD	COSMIC	10.919	Loss
Other_PLK_PLK1_PLK1_ST	Q9Y265	RUVBL1	P53350	PLK1	T239	D242N	242	Missense	distal	3	no	16.439	16.239	PhosphoSitePlus	COSMIC	10.919	Down-regulation
Other_PLK_PLK1_PLK1_ST	Q9Y265	RUVBL1	P53350	PLK1	S322	H316Q	316	Missense	distal	-6	no	11.200	11.188	EPSD	COSMIC	10.919	Down-regulation
Other_PLK_PLK1_PLK1_ST	Q53EZ4	CEP55	P53350	PLK1	S23	E24K	24	Missense	proximal	1	no	11.342	10.891	EPSD	COSMIC	10.919	Loss
Other_PLK_PLK1_PLK1_ST	Q53EZ4	CEP55	P53350	PLK1	S23	K29Q	29	Missense	distal	6	no	11.342	11.271	EPSD	COSMIC	10.919	Down-regulation
Other_PLK_PLK1_PLK1_ST	Q53EZ4	CEP55	P53350	PLK1	T25	E24K	24	Missense	proximal	-1	no	11.329	10.758	EPSD	COSMIC	10.919	Loss
Other_PLK_PLK1_PLK1_ST	Q53EZ4	CEP55	P53350	PLK1	T25	K29Q	29	Missense	distal	4	no	11.329	11.299	EPSD	COSMIC	10.919	Down-regulation
Other_PLK_PLK1_PLK1_ST	Q53EZ4	CEP55	P53350	PLK1	T26	E24K	24	Missense	proximal	-2	no	12.144	9.266	EPSD	COSMIC	10.919	Loss
Other_PLK_PLK1_PLK1_ST	Q53EZ4	CEP55	P53350	PLK1	T26	K29Q	29	Missense	distal	3	no	12.144	12.242	EPSD	COSMIC	10.919	Up-regulation
Other_PLK_PLK1_PLK1_ST	Q00613	HSF1	P53350	PLK1	S216	L211P	211	Missense	distal	-5	no	12.468	12.066	PhosphoSitePlus	COSMIC	10.919	Down-regulation
Other_PLK_PLK1_PLK1_ST	Q00613	HSF1	P53350	PLK1	S216	L211R	211	Missense	distal	-5	no	12.468	12.488	PhosphoSitePlus	COSMIC	10.919	Up-regulation
Other_PLK_PLK1_PLK1_ST	Q00613	HSF1	P53350	PLK1	S221	R227Q	227	Missense	distal	6	no	11.236	11.524	EPSD	COSMIC;GDSC	10.919	Up-regulation
Other_PLK_PLK1_PLK1_ST	Q00613	HSF1	P53350	PLK1	S248	S244F	244	Missense	distal	-4	no	11.043	10.725	EPSD	COSMIC	10.919	Loss
Other_PLK_PLK1_PLK1_ST	Q00613	HSF1	P53350	PLK1	S314	R309G	309	Missense	distal	-5	no	11.515	11.230	EPSD	COSMIC	10.919	Down-regulation
Other_PLK_PLK1_PLK1_ST	Q00613	HSF1	P53350	PLK1	S314	P318T	318	Missense	distal	4	no	11.515	11.644	EPSD	COSMIC	10.919	Up-regulation
Other_PLK_PLK1_PLK1_ST	Q00613	HSF1	P53350	PLK1	S333	L330V	330	Missense	distal	-3	no	13.189	12.539	EPSD	COSMIC	10.919	Down-regulation
Other_PLK_PLK1_PLK1_ST	Q00613	HSF1	P53350	PLK1	S333	P327Q	327	Missense	distal	-6	no	13.189	13.812	EPSD	COSMIC	10.919	Up-regulation
Other_PLK_PLK1_PLK1_ST	Q00613	HSF1	P53350	PLK1	S333	R336W	336	Missense	distal	3	no	13.189	12.961	EPSD	COSMIC	10.919	Down-regulation
Other_PLK_PLK1_PLK1_ST	Q00613	HSF1	P53350	PLK1	T355	D356N	356	Missense	proximal	1	no	11.033	10.838	EPSD	COSMIC	10.919	Loss
Other_PLK_PLK1_PLK1_ST	Q00613	HSF1	P53350	PLK1	T355	T349M	349	Missense	distal	-6	no	11.033	11.018	EPSD	COSMIC	10.919	Down-regulation
Other_PLK_PLK1_PLK1_ST	Q00613	HSF1	P53350	PLK1	T355	H354Y	354	Missense	proximal	-1	no	11.033	11.308	EPSD	COSMIC	10.919	Up-regulation
Other_PLK_PLK1_PLK1_ST	Q00613	HSF1	P53350	PLK1	T355	E358K	358	Missense	distal	3	no	11.033	10.827	EPSD	COSMIC	10.919	Loss
Other_PLK_PLK1_PLK1_ST	Q00613	HSF1	P53350	PLK1	S457	P452H	452	Missense	distal	-5	no	11.726	11.344	EPSD	COSMIC	10.919	Down-regulation
Other_PLK_PLK1_PLK1_ST	Q00613	HSF1	P53350	PLK1	S513	E519K	519	Missense	distal	6	no	11.967	11.898	EPSD	COSMIC	10.919	Down-regulation
Other_PLK_PLK1_PLK1_ST	P36507	MAP2K2	P53350	PLK1	T17	P22S	22	Missense	distal	5	no	10.988	10.600	EPSD	COSMIC;CCLE	10.919	Loss
Other_PLK_PLK1_PLK1_ST	P36507	MAP2K2	P53350	PLK1	T17	A19V	19	Missense	proximal	2	no	10.988	11.431	EPSD	COSMIC	10.919	Up-regulation
Other_PLK_PLK1_PLK1_ST	P36507	MAP2K2	P53350	PLK1	T17	P22L	22	Missense	distal	5	no	10.988	10.254	EPSD	COSMIC	10.919	Loss
Other_PLK_PLK1_PLK1_ST	P36507	MAP2K2	P53350	PLK1	T17	I14V	14	Missense	distal	-3	no	10.988	10.712	EPSD	COSMIC	10.919	Loss
Other_PLK_PLK1_PLK1_ST	P36507	MAP2K2	P53350	PLK1	S222	G217C	217	Missense	distal	-5	no	13.658	13.278	EPSD;PhosphoSitePlus	COSMIC	10.919	Down-regulation
Other_PLK_PLK1_PLK1_ST	P36507	MAP2K2	P53350	PLK1	S222	S222Y	222	Missense	central	0	yes	13.658	0.000	EPSD;PhosphoSitePlus	COSMIC	10.919	Loss
Other_PLK_PLK1_PLK1_ST	P36507	MAP2K2	P53350	PLK1	S222	M223V	223	Missense	proximal	1	no	13.658	12.502	EPSD;PhosphoSitePlus	COSMIC	10.919	Down-regulation
Other_PLK_PLK1_PLK1_ST	P36507	MAP2K2	P53350	PLK1	S222	V215E	215	Missense	distal	-7	no	13.658	13.894	EPSD;PhosphoSitePlus	COSMIC	10.919	Up-regulation
Other_PLK_PLK1_PLK1_ST	P36507	MAP2K2	P53350	PLK1	S226	R231H	231	Missense	distal	5	no	14.657	14.006	PhosphoSitePlus;EPSD	COSMIC	10.919	Down-regulation
Other_PLK_PLK1_PLK1_ST	P36507	MAP2K2	P53350	PLK1	S226	S222Y	222	Missense	distal	-4	no	14.657	13.970	PhosphoSitePlus;EPSD	COSMIC	10.919	Down-regulation
Other_PLK_PLK1_PLK1_ST	P36507	MAP2K2	P53350	PLK1	S226	M223V	223	Missense	distal	-3	no	14.657	14.529	PhosphoSitePlus;EPSD	COSMIC	10.919	Down-regulation
Other_PLK_PLK1_PLK1_ST	P30626	SRI	P53350	PLK1	S87	E94D	94	Missense	distal	7	no	12.711	12.707	EPSD	COSMIC;GDSC;CCLE	10.919	Down-regulation
Other_PLK_PLK1_PLK1_ST	P30626	SRI	P53350	PLK1	S87	G91S	91	Missense	distal	4	no	12.711	12.796	EPSD	COSMIC	10.919	Up-regulation
Other_PLK_PLK1_PLK1_ST	P30626	SRI	P53350	PLK1	S117	E124K	124	Missense	distal	7	no	11.244	11.317	EPSD	COSMIC	10.919	Up-regulation
Other_PLK_PLK1_PLK1_ST	P30626	SRI	P53350	PLK1	S117	T119I	119	Missense	proximal	2	no	11.244	12.305	EPSD	COSMIC	10.919	Up-regulation
Other_PLK_PLK1_PLK1_ST	P30626	SRI	P53350	PLK1	S149	T155I	155	Missense	distal	6	no	11.805	11.531	EPSD	COSMIC	10.919	Down-regulation
Other_PLK_PLK1_PLK1_ST	P30626	SRI	P53350	PLK1	S172	A168T	168	Missense	distal	-4	no	12.409	12.007	EPSD	COSMIC	10.919	Down-regulation
Other_PLK_PLK1_PLK1_ST	Q07817	BCL2L1	P53350	PLK1	S62	A64T	64	Missense	proximal	2	no	12.434	12.033	PhosphoSitePlus	COSMIC;GDSC;CCLE	10.919	Down-regulation
Other_PLK_PLK1_PLK1_ST	Q07817	BCL2L1	P53350	PLK1	S62	A60V	60	Missense	proximal	-2	no	12.434	12.393	PhosphoSitePlus	COSMIC;GDSC;CCLE	10.919	Down-regulation
Other_PLK_PLK1_PLK1_ST	P54274	TERF1	P53350	PLK1	T254	S252L	252	Missense	proximal	-2	no	14.874	13.926	EPSD	COSMIC	10.919	Down-regulation
Other_PLK_PLK1_PLK1_ST	P54274	TERF1	P53350	PLK1	T358	A357D	357	Missense	proximal	-1	no	10.139	11.399	EPSD	COSMIC	10.919	Gain
Other_PLK_PLK1_PLK1_ST	P54274	TERF1	P53350	PLK1	S435	S434C	434	Missense	proximal	-1	no	12.324	10.464	PhosphoSitePlus	COSMIC	10.919	Loss
Other_PLK_PLK1_PLK1_ST	P54274	TERF1	P53350	PLK1	S435	I433N	433	Missense	proximal	-2	no	12.324	14.298	PhosphoSitePlus	COSMIC	10.919	Up-regulation
Other_PLK_PLK1_PLK1_ST	Q2NKX8	ERCC6L	P53350	PLK1	S694	E692K	692	Missense	proximal	-2	no	11.436	8.558	EPSD	COSMIC	10.919	Loss
Other_PLK_PLK1_PLK1_ST	Q2NKX8	ERCC6L	P53350	PLK1	S769	D767Y	767	Missense	proximal	-2	no	11.436	9.894	EPSD	COSMIC;GDSC;CCLE	10.919	Loss
Other_PLK_PLK1_PLK1_ST	Q2NKX8	ERCC6L	P53350	PLK1	S769	V776A	776	Missense	distal	7	no	11.436	11.413	EPSD	COSMIC	10.919	Down-regulation
Other_PLK_PLK1_PLK1_ST	Q2NKX8	ERCC6L	P53350	PLK1	S769	E765D	765	Missense	distal	-4	no	11.436	11.252	EPSD	COSMIC	10.919	Down-regulation
Other_PLK_PLK1_PLK1_ST	Q2NKX8	ERCC6L	P53350	PLK1	S770	E765D	765	Missense	distal	-5	no	10.601	10.943	EPSD	COSMIC	10.919	Gain
Other_PLK_PLK1_PLK1_ST	Q2NKX8	ERCC6L	P53350	PLK1	S774	D767Y	767	Missense	distal	-7	no	10.956	10.694	EPSD	COSMIC;GDSC;CCLE	10.919	Loss
Other_PLK_PLK1_PLK1_ST	Q2NKX8	ERCC6L	P53350	PLK1	S774	V776A	776	Missense	proximal	2	no	10.956	10.513	EPSD	COSMIC	10.919	Loss
Other_PLK_PLK1_PLK1_ST	Q2NKX8	ERCC6L	P53350	PLK1	S774	P781L	781	Missense	distal	7	no	10.956	10.927	EPSD	COSMIC	10.919	Down-regulation
Other_PLK_PLK1_PLK1_ST	Q2NKX8	ERCC6L	P53350	PLK1	T797	G804C	804	Missense	distal	7	no	11.540	11.610	EPSD	COSMIC	10.919	Up-regulation
Other_PLK_PLK1_PLK1_ST	Q2NKX8	ERCC6L	P53350	PLK1	T797	V796A	796	Missense	proximal	-1	no	11.540	12.030	EPSD	COSMIC	10.919	Up-regulation
Other_PLK_PLK1_PLK1_ST	Q2NKX8	ERCC6L	P53350	PLK1	T797	S790Y	790	Missense	distal	-7	no	11.540	10.928	EPSD	COSMIC	10.919	Down-regulation
Other_PLK_PLK1_PLK1_ST	Q2NKX8	ERCC6L	P53350	PLK1	T798	V796A	796	Missense	proximal	-2	no	10.896	10.936	EPSD	COSMIC	10.919	Gain
Other_PLK_PLK1_PLK1_ST	Q2NKX8	ERCC6L	P53350	PLK1	S835	N840S	840	Missense	distal	5	no	12.949	13.552	EPSD	COSMIC;GDSC	10.919	Up-regulation
Other_PLK_PLK1_PLK1_ST	Q2NKX8	ERCC6L	P53350	PLK1	S835	L830F	830	Missense	distal	-5	no	12.949	12.024	EPSD	COSMIC	10.919	Down-regulation
Other_PLK_PLK1_PLK1_ST	Q2NKX8	ERCC6L	P53350	PLK1	S946	A944E	944	Missense	proximal	-2	no	10.422	12.600	EPSD	COSMIC;GDSC	10.919	Gain
Other_PLK_PLK1_PLK1_ST	Q2NKX8	ERCC6L	P53350	PLK1	S980	E978Q	978	Missense	proximal	-2	no	12.651	9.992	EPSD	COSMIC;GDSC;CCLE	10.919	Loss
Other_PLK_PLK1_PLK1_ST	Q2NKX8	ERCC6L	P53350	PLK1	S1036	S1042N	1042	Missense	distal	6	no	16.554	16.605	EPSD	COSMIC	10.919	Up-regulation
Other_PLK_PLK1_PLK1_ST	Q2NKX8	ERCC6L	P53350	PLK1	S1041	S1042N	1042	Missense	proximal	1	no	10.458	11.198	EPSD	COSMIC	10.919	Gain
Other_PLK_PLK1_PLK1_ST	Q2NKX8	ERCC6L	P53350	PLK1	T1063	Q1058K	1058	Missense	distal	-5	no	10.926	11.127	PhosphoSitePlus	COSMIC	10.919	Up-regulation
Other_PLK_PLK1_PLK1_ST	Q2NKX8	ERCC6L	P53350	PLK1	S1077	V1083A	1083	Missense	distal	6	no	11.362	11.537	EPSD	COSMIC	10.919	Up-regulation
Other_PLK_PLK1_PLK1_ST	Q2NKX8	ERCC6L	P53350	PLK1	S1082	S1077T	1077	Missense	distal	-5	no	10.800	11.015	EPSD	COSMIC	10.919	Gain
Other_PLK_PLK1_PLK1_ST	Q2NKX8	ERCC6L	P53350	PLK1	S1086	R1091K	1091	Missense	distal	5	no	12.621	11.996	EPSD	COSMIC;GDSC;CCLE	10.919	Down-regulation
Other_PLK_PLK1_PLK1_ST	Q2NKX8	ERCC6L	P53350	PLK1	S1086	S1092C	1092	Missense	distal	6	no	12.621	11.689	EPSD	COSMIC	10.919	Down-regulation
Other_PLK_PLK1_PLK1_ST	Q2NKX8	ERCC6L	P53350	PLK1	S1086	V1083A	1083	Missense	distal	-3	no	12.621	13.020	EPSD	COSMIC	10.919	Up-regulation
Other_PLK_PLK1_PLK1_ST	Q2NKX8	ERCC6L	P53350	PLK1	S1086	S1089Y	1089	Missense	distal	3	no	12.621	12.441	EPSD	COSMIC	10.919	Down-regulation
Other_PLK_PLK1_PLK1_ST	Q2NKX8	ERCC6L	P53350	PLK1	S1117	M1110R	1110	Missense	distal	-7	no	11.840	11.773	EPSD	COSMIC	10.919	Down-regulation
Other_PLK_PLK1_PLK1_ST	Q2NKX8	ERCC6L	P53350	PLK1	S1117	R1113I	1113	Missense	distal	-4	no	11.840	12.440	EPSD	COSMIC	10.919	Up-regulation
Other_PLK_PLK1_PLK1_ST	Q2NKX8	ERCC6L	P53350	PLK1	S1117	P1123L	1123	Missense	distal	6	no	11.840	11.735	EPSD	COSMIC	10.919	Down-regulation
Other_PLK_PLK1_PLK1_ST	Q2NKX8	ERCC6L	P53350	PLK1	S1118	R1113I	1113	Missense	distal	-5	no	13.732	13.416	EPSD	COSMIC	10.919	Down-regulation
Other_PLK_PLK1_PLK1_ST	Q2NKX8	ERCC6L	P53350	PLK1	S1118	P1123L	1123	Missense	distal	5	no	13.732	12.998	EPSD	COSMIC	10.919	Down-regulation
Other_PLK_PLK1_PLK1_ST	Q2NKX8	ERCC6L	P53350	PLK1	S1134	E1128K	1128	Missense	distal	-6	no	11.020	10.446	EPSD	COSMIC	10.919	Loss
Other_PLK_PLK1_PLK1_ST	Q2NKX8	ERCC6L	P53350	PLK1	S1134	V1131G	1131	Missense	distal	-3	no	11.020	11.668	EPSD	COSMIC	10.919	Up-regulation
Other_PLK_PLK1_PLK1_ST	Q2NKX8	ERCC6L	P53350	PLK1	S1173	P1179L	1179	Missense	distal	6	no	11.507	11.402	EPSD	COSMIC	10.919	Down-regulation
Other_PLK_PLK1_PLK1_ST	Q2NKX8	ERCC6L	P53350	PLK1	S1173	P1177R	1177	Missense	distal	4	no	11.507	10.884	EPSD	COSMIC	10.919	Loss
Other_PLK_PLK1_PLK1_ST	Q2NKX8	ERCC6L	P53350	PLK1	S1242	Q1246P	1246	Missense	distal	4	no	12.027	12.120	EPSD	COSMIC	10.919	Up-regulation
Other_PLK_PLK1_PLK1_ST	Q2NKX8	ERCC6L	P53350	PLK1	S1242	L1241S	1241	Missense	proximal	-1	no	12.027	12.487	EPSD	COSMIC	10.919	Up-regulation
Other_PLK_PLK1_PLK1_ST	Q16143	SNCB	P53350	PLK1	S118	Y119F	119	Missense	proximal	1	no	10.054	12.364	PhosphoSitePlus	COSMIC	10.919	Gain
Other_PLK_PLK1_PLK1_ST	Q2M2Z5	KIZ	P53350	PLK1	S165	D172N	172	Missense	distal	7	no	11.021	11.103	EPSD	COSMIC	10.919	Up-regulation
Other_PLK_PLK1_PLK1_ST	Q2M2Z5	KIZ	P53350	PLK1	S165	D172Y	172	Missense	distal	7	no	11.021	11.103	EPSD	COSMIC	10.919	Up-regulation
Other_PLK_PLK1_PLK1_ST	Q2M2Z5	KIZ	P53350	PLK1	S187	P191R	191	Missense	distal	4	no	13.389	12.766	EPSD	COSMIC	10.919	Down-regulation
Other_PLK_PLK1_PLK1_ST	Q2M2Z5	KIZ	P53350	PLK1	S187	K184N	184	Missense	distal	-3	no	13.389	13.207	EPSD	COSMIC	10.919	Down-regulation
Other_PLK_PLK1_PLK1_ST	Q2M2Z5	KIZ	P53350	PLK1	S187	P189T	189	Missense	proximal	2	no	13.389	14.225	EPSD	COSMIC	10.919	Up-regulation
Other_PLK_PLK1_PLK1_ST	Q2M2Z5	KIZ	P53350	PLK1	S187	Q181H	181	Missense	distal	-6	no	13.389	13.401	EPSD	COSMIC	10.919	Up-regulation
Other_PLK_PLK1_PLK1_ST	Q2M2Z5	KIZ	P53350	PLK1	S187	K184R	184	Missense	distal	-3	no	13.389	13.850	EPSD	COSMIC	10.919	Up-regulation
Other_PLK_PLK1_PLK1_ST	Q2M2Z5	KIZ	P53350	PLK1	S187	P189L	189	Missense	proximal	2	no	13.389	14.937	EPSD	COSMIC	10.919	Up-regulation
Other_PLK_PLK1_PLK1_ST	Q2M2Z5	KIZ	P53350	PLK1	S263	G261D	261	Missense	proximal	-2	no	10.363	13.685	EPSD	COSMIC	10.919	Gain
Other_PLK_PLK1_PLK1_ST	Q2M2Z5	KIZ	P53350	PLK1	S266	G261C	261	Missense	distal	-5	no	11.804	11.423	EPSD	COSMIC	10.919	Down-regulation
Other_PLK_PLK1_PLK1_ST	Q2M2Z5	KIZ	P53350	PLK1	S266	A272P	272	Missense	distal	6	no	11.804	11.665	EPSD	COSMIC	10.919	Down-regulation
Other_PLK_PLK1_PLK1_ST	Q2M2Z5	KIZ	P53350	PLK1	S266	R259H	259	Missense	distal	-7	no	11.804	12.183	EPSD	COSMIC	10.919	Up-regulation
Other_PLK_PLK1_PLK1_ST	Q2M2Z5	KIZ	P53350	PLK1	S266	G261D	261	Missense	distal	-5	no	11.804	11.649	EPSD	COSMIC	10.919	Down-regulation
Other_PLK_PLK1_PLK1_ST	Q2M2Z5	KIZ	P53350	PLK1	S266	K262R	262	Missense	distal	-4	no	11.804	11.630	EPSD	COSMIC	10.919	Down-regulation
Other_PLK_PLK1_PLK1_ST	Q2M2Z5	KIZ	P53350	PLK1	S266	K262N	262	Missense	distal	-4	no	11.804	12.062	EPSD	COSMIC	10.919	Up-regulation
Other_PLK_PLK1_PLK1_ST	Q2M2Z5	KIZ	P53350	PLK1	S276	R279Q	279	Missense	distal	3	no	10.750	10.946	EPSD	COSMIC	10.919	Gain
Other_PLK_PLK1_PLK1_ST	Q2M2Z5	KIZ	P53350	PLK1	S276	P277L	277	Missense	proximal	1	no	10.750	11.596	EPSD	COSMIC	10.919	Gain
Other_PLK_PLK1_PLK1_ST	Q2M2Z5	KIZ	P53350	PLK1	T379	S373L	373	Missense	distal	-6	no	13.223	12.889	PhosphoSitePlus	COSMIC	10.919	Down-regulation
Other_PLK_PLK1_PLK1_ST	Q2M2Z5	KIZ	P53350	PLK1	T379	S376I	376	Missense	distal	-3	no	13.223	13.622	PhosphoSitePlus	COSMIC	10.919	Up-regulation
Other_PLK_PLK1_PLK1_ST	Q2M2Z5	KIZ	P53350	PLK1	T379	S376R	376	Missense	distal	-3	no	13.223	14.055	PhosphoSitePlus	COSMIC	10.919	Up-regulation
Other_PLK_PLK1_PLK1_ST	Q2M2Z5	KIZ	P53350	PLK1	T379	S381L	381	Missense	proximal	2	no	13.223	13.295	PhosphoSitePlus	COSMIC	10.919	Up-regulation
Other_PLK_PLK1_PLK1_ST	Q2M2Z5	KIZ	P53350	PLK1	T379	S373N	373	Missense	distal	-6	no	13.223	13.026	PhosphoSitePlus	COSMIC	10.919	Down-regulation
Other_PLK_PLK1_PLK1_ST	Q2M2Z5	KIZ	P53350	PLK1	T433	N428D	428	Missense	distal	-5	no	10.689	10.985	EPSD	COSMIC	10.919	Gain
Other_PLK_PLK1_PLK1_ST	Q2M2Z5	KIZ	P53350	PLK1	S439	T445A	445	Missense	distal	6	no	11.136	11.144	EPSD	COSMIC	10.919	Up-regulation
Other_PLK_PLK1_PLK1_ST	Q2M2Z5	KIZ	P53350	PLK1	S439	S435C	435	Missense	distal	-4	no	11.136	10.324	EPSD	COSMIC	10.919	Loss
Other_PLK_PLK1_PLK1_ST	Q2M2Z5	KIZ	P53350	PLK1	S439	S435R	435	Missense	distal	-4	no	11.136	10.570	EPSD	COSMIC	10.919	Loss
Other_PLK_PLK1_PLK1_ST	Q2M2Z5	KIZ	P53350	PLK1	S458	S458L	458	Missense	central	0	yes	11.780	0.000	EPSD	COSMIC	10.919	Loss
Other_PLK_PLK1_PLK1_ST	Q2M2Z5	KIZ	P53350	PLK1	S458	V465E	465	Missense	distal	7	no	11.780	11.709	EPSD	COSMIC	10.919	Down-regulation
Other_PLK_PLK1_PLK1_ST	Q2M2Z5	KIZ	P53350	PLK1	S458	V460I	460	Missense	proximal	2	no	11.780	11.997	EPSD	COSMIC	10.919	Up-regulation
Other_PLK_PLK1_PLK1_ST	Q2M2Z5	KIZ	P53350	PLK1	S458	D459H	459	Missense	proximal	1	no	11.780	11.077	EPSD	COSMIC	10.919	Down-regulation
Other_PLK_PLK1_PLK1_ST	Q2M2Z5	KIZ	P53350	PLK1	S458	Q454E	454	Missense	distal	-4	no	11.780	12.048	EPSD	COSMIC	10.919	Up-regulation
Other_PLK_PLK1_PLK1_ST	Q2M2Z5	KIZ	P53350	PLK1	S478	E481Q	481	Missense	distal	3	no	13.437	13.329	EPSD	COSMIC	10.919	Down-regulation
Other_PLK_PLK1_PLK1_ST	Q2M2Z5	KIZ	P53350	PLK1	S478	N477D	477	Missense	proximal	-1	no	13.437	14.370	EPSD	COSMIC	10.919	Up-regulation
Other_PLK_PLK1_PLK1_ST	Q2M2Z5	KIZ	P53350	PLK1	S478	T471N	471	Missense	distal	-7	no	13.437	13.236	EPSD	COSMIC	10.919	Down-regulation
Other_PLK_PLK1_PLK1_ST	Q2M2Z5	KIZ	P53350	PLK1	S503	R497S	497	Missense	distal	-6	no	10.623	11.071	EPSD	COSMIC	10.919	Gain
Other_PLK_PLK1_PLK1_ST	Q2M2Z5	KIZ	P53350	PLK1	S507	L510V	510	Missense	distal	3	no	11.278	11.577	EPSD	COSMIC	10.919	Up-regulation
Other_PLK_PLK1_PLK1_ST	Q2M2Z5	KIZ	P53350	PLK1	S507	S509R	509	Missense	proximal	2	no	11.278	10.551	EPSD	COSMIC	10.919	Loss
Other_PLK_PLK1_PLK1_ST	Q2M2Z5	KIZ	P53350	PLK1	S507	S509I	509	Missense	proximal	2	no	11.278	11.700	EPSD	COSMIC	10.919	Up-regulation
Other_PLK_PLK1_PLK1_ST	Q2M2Z5	KIZ	P53350	PLK1	S507	S506L	506	Missense	proximal	-1	no	11.278	10.818	EPSD	COSMIC	10.919	Loss
Other_PLK_PLK1_PLK1_ST	Q2M2Z5	KIZ	P53350	PLK1	S507	S512Y	512	Missense	distal	5	no	11.278	11.121	EPSD	COSMIC	10.919	Down-regulation
Other_PLK_PLK1_PLK1_ST	Q2M2Z5	KIZ	P53350	PLK1	S616	E614Q	614	Missense	proximal	-2	no	13.910	11.251	EPSD	COSMIC	10.919	Down-regulation
Other_PLK_PLK1_PLK1_ST	Q2M2Z5	KIZ	P53350	PLK1	S616	S613L	613	Missense	distal	-3	no	13.910	14.684	EPSD	COSMIC	10.919	Up-regulation
Other_PLK_PLK1_PLK1_ST	Q2M2Z5	KIZ	P53350	PLK1	S616	K610T	610	Missense	distal	-6	no	13.910	14.262	EPSD	COSMIC	10.919	Up-regulation
Other_PLK_PLK1_PLK1_ST	Q2M2Z5	KIZ	P53350	PLK1	S618	S613L	613	Missense	distal	-5	no	10.625	11.289	EPSD	COSMIC	10.919	Gain
Other_PLK_PLK1_PLK1_ST	Q2M2Z5	KIZ	P53350	PLK1	S647	W644L	644	Missense	distal	-3	no	14.904	15.628	EPSD	COSMIC	10.919	Up-regulation
Other_PLK_PLK1_PLK1_ST	Q2M2Z5	KIZ	P53350	PLK1	S647	N641K	641	Missense	distal	-6	no	14.904	14.646	EPSD	COSMIC	10.919	Down-regulation
Other_PLK_PLK1_PLK1_ST	Q2M2Z5	KIZ	P53350	PLK1	S650	E655Q	655	Missense	distal	5	no	13.964	13.805	EPSD	COSMIC	10.919	Down-regulation
Other_PLK_PLK1_PLK1_ST	Q2M2Z5	KIZ	P53350	PLK1	S650	W644L	644	Missense	distal	-6	no	13.964	14.534	EPSD	COSMIC	10.919	Up-regulation
Other_PLK_PLK1_PLK1_ST	Q2M2Z5	KIZ	P53350	PLK1	S650	A656T	656	Missense	distal	6	no	13.964	13.957	EPSD	COSMIC	10.919	Down-regulation
Other_PLK_PLK1_PLK1_ST	Q2M2Z5	KIZ	P53350	PLK1	S652	E655Q	655	Missense	distal	3	no	13.952	13.844	EPSD	COSMIC	10.919	Down-regulation
Other_PLK_PLK1_PLK1_ST	Q2M2Z5	KIZ	P53350	PLK1	S652	A656T	656	Missense	distal	4	no	13.952	13.959	EPSD	COSMIC	10.919	Up-regulation
Other_PLK_PLK1_PLK1_ST	Q2M2Z5	KIZ	P53350	PLK1	S668	D666N	666	Missense	proximal	-2	no	13.703	12.460	EPSD	COSMIC	10.919	Down-regulation
Other_PLK_PLK1_PLK1_ST	Q2M2Z5	KIZ	P53350	PLK1	S668	D666G	666	Missense	proximal	-2	no	13.703	10.381	EPSD	COSMIC	10.919	Loss
Other_PLK_PLK1_PLK1_ST	Q2M2Z5	KIZ	P53350	PLK1	S668	D667N	667	Missense	proximal	-1	no	13.703	12.769	EPSD	COSMIC	10.919	Down-regulation
Other_PLK_PLK1_PLK1_ST	Q2M2Z5	KIZ	P53350	PLK1	S668	D669H	669	Missense	proximal	1	no	13.703	13.000	EPSD	COSMIC	10.919	Down-regulation
Other_PLK_PLK1_PLK1_ST	Q06609	RAD51	P53350	PLK1	S14	G21D	21	Missense	distal	7	no	12.749	12.724	PhosphoSitePlus	COSMIC	10.919	Down-regulation
Other_PLK_PLK1_PLK1_ST	Q06609	RAD51	P53350	PLK1	S14	E17K	17	Missense	distal	3	no	12.749	12.543	PhosphoSitePlus	COSMIC	10.919	Down-regulation
Other_PLK_PLK1_PLK1_ST	Q06609	RAD51	P53350	PLK1	S14	D12N	12	Missense	proximal	-2	no	12.749	11.506	PhosphoSitePlus	COSMIC	10.919	Down-regulation
Other_PLK_PLK1_PLK1_ST	Q06609	RAD51	P53350	PLK1	S317	C312S	312	Missense	distal	-5	no	12.576	12.558	EPSD	COSMIC	10.919	Down-regulation
Other_PLK_PLK1_PLK1_ST	Q06609	RAD51	P53350	PLK1	S317	P318L	318	Missense	proximal	1	no	12.576	13.422	EPSD	COSMIC	10.919	Up-regulation
Other_PLK_PLK1_PLK1_ST	Q06609	RAD51	P53350	PLK1	S317	S317F	317	Missense	central	0	yes	12.576	0.000	EPSD	COSMIC	10.919	Loss
Other_PLK_PLK1_PLK1_ST	Q06609	RAD51	P53350	PLK1	S317	C312Y	312	Missense	distal	-5	no	12.576	12.656	EPSD	COSMIC	10.919	Up-regulation
Other_PLK_PLK1_PLK1_ST	Q06609	RAD51	P53350	PLK1	S317	E324K	324	Missense	distal	7	no	12.576	12.649	EPSD	COSMIC	10.919	Up-regulation
Other_PLK_PLK1_PLK1_ST	P46937	YAP1	P53350	PLK1	T63	E62D	62	Missense	proximal	-1	no	10.363	11.159	EPSD	COSMIC	10.919	Gain
Other_PLK_PLK1_PLK1_ST	P46937	YAP1	P53350	PLK1	S127	L132R	132	Missense	distal	5	no	10.378	11.069	EPSD	COSMIC	10.919	Gain
Other_PLK_PLK1_PLK1_ST	P46937	YAP1	P53350	PLK1	S131	L132R	132	Missense	proximal	1	no	11.213	8.081	EPSD	COSMIC	10.919	Loss
Other_PLK_PLK1_PLK1_ST	P46937	YAP1	P53350	PLK1	S131	Q133H	133	Missense	proximal	2	no	11.213	11.590	EPSD	COSMIC	10.919	Up-regulation
Other_PLK_PLK1_PLK1_ST	P46937	YAP1	P53350	PLK1	S131	S127F	127	Missense	distal	-4	no	11.213	10.895	EPSD	COSMIC	10.919	Loss
Other_PLK_PLK1_PLK1_ST	P46937	YAP1	P53350	PLK1	S131	A125G	125	Missense	distal	-6	no	11.213	10.702	EPSD	COSMIC	10.919	Loss
Other_PLK_PLK1_PLK1_ST	P46937	YAP1	P53350	PLK1	S164	D170N	170	Missense	distal	6	no	12.625	12.405	EPSD	COSMIC	10.919	Down-regulation
Other_PLK_PLK1_PLK1_ST	P46937	YAP1	P53350	PLK1	S164	I167T	167	Missense	distal	3	no	12.625	12.458	EPSD	COSMIC	10.919	Down-regulation
Other_PLK_PLK1_PLK1_ST	P46937	YAP1	P53350	PLK1	S164	Q162R	162	Missense	proximal	-2	no	12.625	12.800	EPSD	COSMIC	10.919	Up-regulation
Other_PLK_PLK1_PLK1_ST	P46937	YAP1	P53350	PLK1	S164	L160H	160	Missense	distal	-4	no	12.625	12.553	EPSD	COSMIC	10.919	Down-regulation
Other_PLK_PLK1_PLK1_ST	P46937	YAP1	P53350	PLK1	S164	E166G	166	Missense	proximal	2	no	12.625	11.636	EPSD	COSMIC	10.919	Down-regulation
Other_PLK_PLK1_PLK1_ST	P46937	YAP1	P53350	PLK1	S184	A180T	180	Missense	distal	-4	no	11.085	10.684	EPSD	COSMIC	10.919	Loss
Other_PLK_PLK1_PLK1_ST	P46937	YAP1	P53350	PLK1	S336	A338T	338	Missense	proximal	2	no	12.334	11.933	EPSD	COSMIC	10.919	Down-regulation
Other_PLK_PLK1_PLK1_ST	P46937	YAP1	P53350	PLK1	S336	M330I	330	Missense	distal	-6	no	12.334	12.521	EPSD	COSMIC;GDSC	10.919	Up-regulation
Other_PLK_PLK1_PLK1_ST	P46937	YAP1	P53350	PLK1	S336	S340A	340	Missense	distal	4	no	12.334	12.135	EPSD	COSMIC;GDSC	10.919	Down-regulation
Other_PLK_PLK1_PLK1_ST	P46937	YAP1	P53350	PLK1	S393	L386P	386	Missense	distal	-7	no	11.794	11.889	EPSD	COSMIC	10.919	Up-regulation
Other_PLK_PLK1_PLK1_ST	P46937	YAP1	P53350	PLK1	S393	D399G	399	Missense	distal	6	no	11.794	11.319	EPSD	COSMIC	10.919	Down-regulation
Other_PLK_PLK1_PLK1_ST	P46937	YAP1	P53350	PLK1	S393	T390I	390	Missense	distal	-3	no	11.794	11.817	EPSD	COSMIC	10.919	Up-regulation
Other_PLK_PLK1_PLK1_ST	P46937	YAP1	P53350	PLK1	S393	E396K	396	Missense	distal	3	no	11.794	11.588	EPSD	COSMIC	10.919	Down-regulation
Other_PLK_PLK1_PLK1_ST	P46937	YAP1	P53350	PLK1	S393	D399H	399	Missense	distal	6	no	11.794	11.000	EPSD	COSMIC	10.919	Down-regulation
Other_PLK_PLK1_PLK1_ST	P46937	YAP1	P53350	PLK1	S393	D395G	395	Missense	proximal	2	no	11.794	10.215	EPSD	COSMIC	10.919	Loss
Other_PLK_PLK1_PLK1_ST	P46937	YAP1	P53350	PLK1	S397	D399G	399	Missense	proximal	2	no	13.138	11.558	EPSD	COSMIC	10.919	Down-regulation
Other_PLK_PLK1_PLK1_ST	P46937	YAP1	P53350	PLK1	S397	T390I	390	Missense	distal	-7	no	13.138	12.684	EPSD	COSMIC	10.919	Down-regulation
Other_PLK_PLK1_PLK1_ST	P46937	YAP1	P53350	PLK1	S397	E396K	396	Missense	proximal	-1	no	13.138	12.566	EPSD	COSMIC	10.919	Down-regulation
Other_PLK_PLK1_PLK1_ST	P46937	YAP1	P53350	PLK1	S397	D399H	399	Missense	proximal	2	no	13.138	13.114	EPSD	COSMIC	10.919	Down-regulation
Other_PLK_PLK1_PLK1_ST	P46937	YAP1	P53350	PLK1	S397	D395G	395	Missense	proximal	-2	no	13.138	9.816	EPSD	COSMIC	10.919	Loss
Other_PLK_PLK1_PLK1_ST	P46937	YAP1	P53350	PLK1	S403	D399G	399	Missense	distal	-4	no	13.822	13.362	EPSD	COSMIC	10.919	Down-regulation
Other_PLK_PLK1_PLK1_ST	P46937	YAP1	P53350	PLK1	S403	E396K	396	Missense	distal	-7	no	13.822	13.518	EPSD	COSMIC	10.919	Down-regulation
Other_PLK_PLK1_PLK1_ST	P46937	YAP1	P53350	PLK1	S403	D399H	399	Missense	distal	-4	no	13.822	13.750	EPSD	COSMIC	10.919	Down-regulation
Other_PLK_PLK1_PLK1_ST	P46937	YAP1	P53350	PLK1	S419	F416L	416	Missense	distal	-3	no	9.557	10.961	EPSD	COSMIC	10.919	Gain
Other_PLK_PLK1_PLK1_ST	P46937	YAP1	P53350	PLK1	S499	L501I	501	Missense	proximal	2	no	11.760	12.110	EPSD	COSMIC	10.919	Up-regulation
Other_PLK_PLK1_PLK1_ST	Q8IWB6	TEX14	P53350	PLK1	S437	K436R	436	Missense	proximal	-1	no	11.879	11.517	PhosphoSitePlus	COSMIC	10.919	Down-regulation
Other_PLK_PLK1_PLK1_ST	Q8IWB6	TEX14	P53350	PLK1	S571	P572L	572	Missense	proximal	1	no	10.477	11.323	EPSD	COSMIC	10.919	Gain
Other_PLK_PLK1_PLK1_ST	Q8IWB6	TEX14	P53350	PLK1	S687	T692I	692	Missense	distal	5	no	10.433	11.336	EPSD	COSMIC	10.919	Gain
Other_PLK_PLK1_PLK1_ST	Q8IWB6	TEX14	P53350	PLK1	S864	Q866H	866	Missense	proximal	2	no	12.771	13.149	EPSD	COSMIC	10.919	Up-regulation
Other_PLK_PLK1_PLK1_ST	Q8IWB6	TEX14	P53350	PLK1	T873	Q866H	866	Missense	distal	-7	no	11.815	11.794	EPSD	COSMIC	10.919	Down-regulation
Other_PLK_PLK1_PLK1_ST	Q8IWB6	TEX14	P53350	PLK1	S1289	S1290F	1290	Missense	proximal	1	no	8.313	11.361	EPSD	COSMIC	10.919	Gain
Other_PLK_PLK1_PLK1_ST	Q8IWB6	TEX14	P53350	PLK1	S1290	S1290F	1290	Missense	central	0	yes	13.312	0.000	EPSD	COSMIC	10.919	Loss
Other_PLK_PLK1_PLK1_ST	Q8IWB6	TEX14	P53350	PLK1	S1290	L1285H	1285	Missense	distal	-5	no	13.312	12.530	EPSD	COSMIC	10.919	Down-regulation
Other_PLK_PLK1_PLK1_ST	Q8IWB6	TEX14	P53350	PLK1	S1290	S1296F	1296	Missense	distal	6	no	13.312	12.736	EPSD	COSMIC	10.919	Down-regulation
Other_PLK_PLK1_PLK1_ST	Q8IWB6	TEX14	P53350	PLK1	S1290	G1295V	1295	Missense	distal	5	no	13.312	12.958	EPSD	COSMIC	10.919	Down-regulation
Other_PLK_PLK1_PLK1_ST	Q8IWB6	TEX14	P53350	PLK1	S1290	R1287T	1287	Missense	distal	-3	no	13.312	12.857	EPSD	COSMIC	10.919	Down-regulation
Other_PLK_PLK1_PLK1_ST	Q96T23	RSF1	P53350	PLK1	S218	P211H	211	Missense	distal	-7	no	13.636	13.730	EPSD	COSMIC	10.919	Up-regulation
Other_PLK_PLK1_PLK1_ST	Q96T23	RSF1	P53350	PLK1	S218	P211L	211	Missense	distal	-7	no	13.636	13.542	EPSD	COSMIC	10.919	Down-regulation
Other_PLK_PLK1_PLK1_ST	Q96T23	RSF1	P53350	PLK1	S218	V212L	212	Missense	distal	-6	no	13.636	13.577	EPSD	COSMIC	10.919	Down-regulation
Other_PLK_PLK1_PLK1_ST	Q96T23	RSF1	P53350	PLK1	S227	D232E	232	Missense	distal	5	no	11.257	10.816	EPSD	COSMIC	10.919	Loss
Other_PLK_PLK1_PLK1_ST	Q96T23	RSF1	P53350	PLK1	S227	E226G	226	Missense	proximal	-1	no	11.257	9.464	EPSD	COSMIC	10.919	Loss
Other_PLK_PLK1_PLK1_ST	Q96T23	RSF1	P53350	PLK1	S314	K316N	316	Missense	proximal	2	no	10.781	11.756	EPSD	COSMIC	10.919	Gain
Other_PLK_PLK1_PLK1_ST	Q96T23	RSF1	P53350	PLK1	S367	E372K	372	Missense	distal	5	no	12.849	12.860	EPSD	COSMIC	10.919	Up-regulation
Other_PLK_PLK1_PLK1_ST	Q96T23	RSF1	P53350	PLK1	S367	T371A	371	Missense	distal	4	no	12.849	12.843	EPSD	COSMIC	10.919	Down-regulation
Other_PLK_PLK1_PLK1_ST	Q96T23	RSF1	P53350	PLK1	S367	E362K	362	Missense	distal	-5	no	12.849	13.093	EPSD	COSMIC	10.919	Up-regulation
Other_PLK_PLK1_PLK1_ST	Q96T23	RSF1	P53350	PLK1	S447	V451A	451	Missense	distal	4	no	12.834	13.097	EPSD	COSMIC	10.919	Up-regulation
Other_PLK_PLK1_PLK1_ST	Q96T23	RSF1	P53350	PLK1	S471	K476E	476	Missense	distal	5	no	10.932	10.921	EPSD	COSMIC	10.919	Down-regulation
Other_PLK_PLK1_PLK1_ST	Q96T23	RSF1	P53350	PLK1	S471	S475P	475	Missense	distal	4	no	10.932	10.610	EPSD	COSMIC	10.919	Loss
Other_PLK_PLK1_PLK1_ST	Q96T23	RSF1	P53350	PLK1	S471	Y472C	472	Missense	proximal	1	no	10.932	10.429	EPSD	COSMIC	10.919	Loss
Other_PLK_PLK1_PLK1_ST	Q96T23	RSF1	P53350	PLK1	S473	K476E	476	Missense	distal	3	no	11.468	11.675	EPSD	COSMIC	10.919	Up-regulation
Other_PLK_PLK1_PLK1_ST	Q96T23	RSF1	P53350	PLK1	S473	S475P	475	Missense	proximal	2	no	11.468	9.992	EPSD	COSMIC	10.919	Loss
Other_PLK_PLK1_PLK1_ST	Q96T23	RSF1	P53350	PLK1	S473	Y472C	472	Missense	proximal	-1	no	11.468	9.272	EPSD	COSMIC	10.919	Loss
Other_PLK_PLK1_PLK1_ST	Q96T23	RSF1	P53350	PLK1	S489	G484R	484	Missense	distal	-5	no	11.324	11.609	EPSD	COSMIC	10.919	Up-regulation
Other_PLK_PLK1_PLK1_ST	Q96T23	RSF1	P53350	PLK1	S492	T499K	499	Missense	distal	7	no	11.401	11.466	EPSD	COSMIC	10.919	Up-regulation
Other_PLK_PLK1_PLK1_ST	Q96T23	RSF1	P53350	PLK1	S515	D512G	512	Missense	distal	-3	no	11.232	11.715	EPSD	COSMIC	10.919	Up-regulation
Other_PLK_PLK1_PLK1_ST	Q96T23	RSF1	P53350	PLK1	S516	D512G	512	Missense	distal	-4	no	13.018	12.559	EPSD	COSMIC	10.919	Down-regulation
Other_PLK_PLK1_PLK1_ST	Q96T23	RSF1	P53350	PLK1	S540	E536K	536	Missense	distal	-4	no	11.496	11.113	EPSD	COSMIC	10.919	Down-regulation
Other_PLK_PLK1_PLK1_ST	Q96T23	RSF1	P53350	PLK1	S540	S543F	543	Missense	distal	3	no	11.496	11.556	EPSD	COSMIC	10.919	Up-regulation
Other_PLK_PLK1_PLK1_ST	Q96T23	RSF1	P53350	PLK1	S544	S551C	551	Missense	distal	7	no	12.136	12.204	EPSD	COSMIC	10.919	Up-regulation
Other_PLK_PLK1_PLK1_ST	Q96T23	RSF1	P53350	PLK1	S544	S543F	543	Missense	proximal	-1	no	12.136	11.597	EPSD	COSMIC	10.919	Down-regulation
Other_PLK_PLK1_PLK1_ST	Q96T23	RSF1	P53350	PLK1	S604	E609G	609	Missense	distal	5	no	10.498	10.973	EPSD	COSMIC	10.919	Gain
Other_PLK_PLK1_PLK1_ST	Q96T23	RSF1	P53350	PLK1	S660	D665H	665	Missense	distal	5	no	10.958	10.503	EPSD	COSMIC	10.919	Loss
Other_PLK_PLK1_PLK1_ST	Q96T23	RSF1	P53350	PLK1	S660	D665G	665	Missense	distal	5	no	10.958	10.992	EPSD	COSMIC	10.919	Up-regulation
Other_PLK_PLK1_PLK1_ST	Q96T23	RSF1	P53350	PLK1	S660	K663N	663	Missense	distal	3	no	10.958	11.030	EPSD	COSMIC	10.919	Up-regulation
Other_PLK_PLK1_PLK1_ST	Q96T23	RSF1	P53350	PLK1	S660	S654N	654	Missense	distal	-6	no	10.958	10.762	EPSD	COSMIC	10.919	Loss
Other_PLK_PLK1_PLK1_ST	Q96T23	RSF1	P53350	PLK1	S660	D665Y	665	Missense	distal	5	no	10.958	10.652	EPSD	COSMIC	10.919	Loss
Other_PLK_PLK1_PLK1_ST	Q96T23	RSF1	P53350	PLK1	S660	S660F	660	Missense	central	0	yes	10.958	0.000	EPSD	COSMIC	10.919	Loss
Other_PLK_PLK1_PLK1_ST	Q96T23	RSF1	P53350	PLK1	T812	E810V	810	Missense	proximal	-2	no	11.720	9.501	EPSD	COSMIC	10.919	Loss
Other_PLK_PLK1_PLK1_ST	Q96T23	RSF1	P53350	PLK1	T817	E810V	810	Missense	distal	-7	no	11.051	10.816	EPSD	COSMIC	10.919	Loss
Other_PLK_PLK1_PLK1_ST	Q96T23	RSF1	P53350	PLK1	S858	E861G	861	Missense	distal	3	no	11.865	11.688	EPSD	COSMIC	10.919	Down-regulation
Other_PLK_PLK1_PLK1_ST	Q96T23	RSF1	P53350	PLK1	S858	R853I	853	Missense	distal	-5	no	11.865	11.550	EPSD	COSMIC	10.919	Down-regulation
Other_PLK_PLK1_PLK1_ST	Q96T23	RSF1	P53350	PLK1	S858	S862C	862	Missense	distal	4	no	11.865	11.339	EPSD	COSMIC;GDSC;CCLE	10.919	Down-regulation
Other_PLK_PLK1_PLK1_ST	Q96T23	RSF1	P53350	PLK1	S858	R851H	851	Missense	distal	-7	no	11.865	12.245	EPSD	COSMIC	10.919	Up-regulation
Other_PLK_PLK1_PLK1_ST	Q96T23	RSF1	P53350	PLK1	S870	S871F	871	Missense	proximal	1	no	10.256	13.304	EPSD	COSMIC	10.919	Gain
Other_PLK_PLK1_PLK1_ST	Q96T23	RSF1	P53350	PLK1	S1053	I1052N	1052	Missense	proximal	-1	no	13.175	13.018	EPSD	COSMIC	10.919	Down-regulation
Other_PLK_PLK1_PLK1_ST	Q96T23	RSF1	P53350	PLK1	S1053	T1054A	1054	Missense	proximal	1	no	13.175	12.713	EPSD	COSMIC	10.919	Down-regulation
Other_PLK_PLK1_PLK1_ST	Q96T23	RSF1	P53350	PLK1	T1056	T1054A	1054	Missense	proximal	-2	no	10.624	11.243	EPSD	COSMIC	10.919	Gain
Other_PLK_PLK1_PLK1_ST	Q96T23	RSF1	P53350	PLK1	S1064	R1071H	1071	Missense	distal	7	no	12.183	12.154	EPSD	COSMIC	10.919	Down-regulation
Other_PLK_PLK1_PLK1_ST	Q96T23	RSF1	P53350	PLK1	S1064	R1071C	1071	Missense	distal	7	no	12.183	12.236	EPSD	COSMIC	10.919	Up-regulation
Other_PLK_PLK1_PLK1_ST	Q96T23	RSF1	P53350	PLK1	S1064	R1071T	1071	Missense	distal	7	no	12.183	12.152	EPSD	COSMIC	10.919	Down-regulation
Other_PLK_PLK1_PLK1_ST	Q96T23	RSF1	P53350	PLK1	S1096	R1090Q	1090	Missense	distal	-6	no	12.211	12.659	EPSD	COSMIC	10.919	Up-regulation
Other_PLK_PLK1_PLK1_ST	Q96T23	RSF1	P53350	PLK1	S1096	D1101E	1101	Missense	distal	5	no	12.211	11.771	EPSD	COSMIC	10.919	Down-regulation
Other_PLK_PLK1_PLK1_ST	Q96T23	RSF1	P53350	PLK1	S1096	R1090L	1090	Missense	distal	-6	no	12.211	12.325	EPSD	COSMIC	10.919	Up-regulation
Other_PLK_PLK1_PLK1_ST	Q96T23	RSF1	P53350	PLK1	S1105	S1112T	1112	Missense	distal	7	no	12.874	12.859	EPSD	COSMIC	10.919	Down-regulation
Other_PLK_PLK1_PLK1_ST	Q96T23	RSF1	P53350	PLK1	S1105	S1112R	1112	Missense	distal	7	no	12.874	12.889	EPSD	COSMIC	10.919	Up-regulation
Other_PLK_PLK1_PLK1_ST	Q96T23	RSF1	P53350	PLK1	S1105	D1101E	1101	Missense	distal	-4	no	12.874	13.058	EPSD	COSMIC	10.919	Up-regulation
Other_PLK_PLK1_PLK1_ST	Q96T23	RSF1	P53350	PLK1	S1180	D1173N	1173	Missense	distal	-7	no	12.544	12.684	EPSD	COSMIC	10.919	Up-regulation
Other_PLK_PLK1_PLK1_ST	Q96T23	RSF1	P53350	PLK1	S1180	D1173Y	1173	Missense	distal	-7	no	12.544	12.282	EPSD	COSMIC	10.919	Down-regulation
Other_PLK_PLK1_PLK1_ST	Q96T23	RSF1	P53350	PLK1	S1180	D1186E	1186	Missense	distal	6	no	12.544	12.394	EPSD	COSMIC	10.919	Down-regulation
Other_PLK_PLK1_PLK1_ST	Q96T23	RSF1	P53350	PLK1	S1180	N1183D	1183	Missense	distal	3	no	12.544	12.744	EPSD	COSMIC	10.919	Up-regulation
Other_PLK_PLK1_PLK1_ST	Q96T23	RSF1	P53350	PLK1	S1192	D1186E	1186	Missense	distal	-6	no	13.469	13.672	EPSD	COSMIC	10.919	Up-regulation
Other_PLK_PLK1_PLK1_ST	Q96T23	RSF1	P53350	PLK1	S1192	S1196G	1196	Missense	distal	4	no	13.469	13.383	EPSD	COSMIC	10.919	Down-regulation
Other_PLK_PLK1_PLK1_ST	Q96T23	RSF1	P53350	PLK1	S1196	R1203Q	1203	Missense	distal	7	no	11.764	11.779	EPSD	COSMIC	10.919	Up-regulation
Other_PLK_PLK1_PLK1_ST	Q96T23	RSF1	P53350	PLK1	S1196	S1196G	1196	Missense	central	0	yes	11.764	0.000	EPSD	COSMIC	10.919	Loss
Other_PLK_PLK1_PLK1_ST	Q96T23	RSF1	P53350	PLK1	S1221	S1226F	1226	Missense	distal	5	no	12.869	12.963	EPSD	COSMIC;GDSC;CCLE	10.919	Up-regulation
Other_PLK_PLK1_PLK1_ST	Q96T23	RSF1	P53350	PLK1	S1221	I1215N	1215	Missense	distal	-6	no	12.869	12.604	EPSD	COSMIC	10.919	Down-regulation
Other_PLK_PLK1_PLK1_ST	Q96T23	RSF1	P53350	PLK1	S1221	E1219G	1219	Missense	proximal	-2	no	12.869	9.941	EPSD	COSMIC	10.919	Loss
Other_PLK_PLK1_PLK1_ST	Q96T23	RSF1	P53350	PLK1	S1221	I1215V	1215	Missense	distal	-6	no	12.869	12.526	EPSD	COSMIC	10.919	Down-regulation
Other_PLK_PLK1_PLK1_ST	Q96T23	RSF1	P53350	PLK1	S1221	D1220N	1220	Missense	proximal	-1	no	12.869	11.936	EPSD	COSMIC	10.919	Down-regulation
Other_PLK_PLK1_PLK1_ST	Q96T23	RSF1	P53350	PLK1	S1226	R1232H	1232	Missense	distal	6	no	11.104	10.888	EPSD	COSMIC	10.919	Loss
Other_PLK_PLK1_PLK1_ST	Q96T23	RSF1	P53350	PLK1	S1226	S1226F	1226	Missense	central	0	yes	11.104	0.000	EPSD	COSMIC;GDSC;CCLE	10.919	Loss
Other_PLK_PLK1_PLK1_ST	Q96T23	RSF1	P53350	PLK1	S1226	E1219G	1219	Missense	distal	-7	no	11.104	10.469	EPSD	COSMIC	10.919	Loss
Other_PLK_PLK1_PLK1_ST	Q96T23	RSF1	P53350	PLK1	S1226	D1220N	1220	Missense	distal	-6	no	11.104	10.991	EPSD	COSMIC	10.919	Down-regulation
Other_PLK_PLK1_PLK1_ST	Q96T23	RSF1	P53350	PLK1	S1229	R1232H	1232	Missense	distal	3	no	11.434	11.565	EPSD	COSMIC	10.919	Up-regulation
Other_PLK_PLK1_PLK1_ST	Q96T23	RSF1	P53350	PLK1	S1229	S1226F	1226	Missense	distal	-3	no	11.434	10.805	EPSD	COSMIC;GDSC;CCLE	10.919	Loss
Other_PLK_PLK1_PLK1_ST	Q96T23	RSF1	P53350	PLK1	S1229	K1234T	1234	Missense	distal	5	no	11.434	11.110	EPSD	COSMIC	10.919	Down-regulation
Other_PLK_PLK1_PLK1_ST	Q96T23	RSF1	P53350	PLK1	S1282	E1288K	1288	Missense	distal	6	no	11.399	11.330	EPSD	COSMIC;GDSC;CCLE	10.919	Down-regulation
Other_PLK_PLK1_PLK1_ST	Q96T23	RSF1	P53350	PLK1	S1282	A1284S	1284	Missense	proximal	2	no	11.399	11.639	EPSD	COSMIC	10.919	Up-regulation
Other_PLK_PLK1_PLK1_ST	Q96T23	RSF1	P53350	PLK1	S1282	E1287K	1287	Missense	distal	5	no	11.399	11.410	EPSD	COSMIC	10.919	Up-regulation
Other_PLK_PLK1_PLK1_ST	Q96T23	RSF1	P53350	PLK1	S1282	E1288D	1288	Missense	distal	6	no	11.399	11.549	EPSD	COSMIC	10.919	Up-regulation
Other_PLK_PLK1_PLK1_ST	Q96T23	RSF1	P53350	PLK1	S1310	D1317Y	1317	Missense	distal	7	no	11.127	11.209	EPSD	COSMIC	10.919	Up-regulation
Other_PLK_PLK1_PLK1_ST	Q96T23	RSF1	P53350	PLK1	S1310	H1315R	1315	Missense	distal	5	no	11.127	11.778	EPSD	COSMIC	10.919	Up-regulation
Other_PLK_PLK1_PLK1_ST	Q96T23	RSF1	P53350	PLK1	S1310	I1303N	1303	Missense	distal	-7	no	11.127	11.380	EPSD	COSMIC	10.919	Up-regulation
Other_PLK_PLK1_PLK1_ST	Q96T23	RSF1	P53350	PLK1	S1310	E1307K	1307	Missense	distal	-3	no	11.127	11.668	EPSD	COSMIC	10.919	Up-regulation
Other_PLK_PLK1_PLK1_ST	Q96T23	RSF1	P53350	PLK1	S1310	E1307D	1307	Missense	distal	-3	no	11.127	11.587	EPSD	COSMIC	10.919	Up-regulation
Other_PLK_PLK1_PLK1_ST	Q96T23	RSF1	P53350	PLK1	S1359	P1360Q	1360	Missense	proximal	1	no	11.192	10.885	PhosphoSitePlus	COSMIC	10.919	Loss
Other_PLK_PLK1_PLK1_ST	Q96T23	RSF1	P53350	PLK1	S1359	G1358W	1358	Missense	proximal	-1	no	11.192	10.762	PhosphoSitePlus	COSMIC	10.919	Loss
Other_PLK_PLK1_PLK1_ST	Q96T23	RSF1	P53350	PLK1	S1359	E1352Q	1352	Missense	distal	-7	no	11.192	11.156	PhosphoSitePlus	COSMIC	10.919	Down-regulation
Other_PLK_PLK1_PLK1_ST	Q96T23	RSF1	P53350	PLK1	S1359	S1364T	1364	Missense	distal	5	no	11.192	10.587	PhosphoSitePlus	COSMIC;GDSC;CCLE	10.919	Loss
Other_PLK_PLK1_PLK1_ST	Q96T23	RSF1	P53350	PLK1	S1364	P1360Q	1360	Missense	distal	-4	no	13.125	12.968	EPSD	COSMIC	10.919	Down-regulation
Other_PLK_PLK1_PLK1_ST	Q96T23	RSF1	P53350	PLK1	S1364	G1358W	1358	Missense	distal	-6	no	13.125	12.767	EPSD	COSMIC	10.919	Down-regulation
Other_PLK_PLK1_PLK1_ST	Q96T23	RSF1	P53350	PLK1	S1364	D1367G	1367	Missense	distal	3	no	13.125	12.882	EPSD	COSMIC	10.919	Down-regulation
Other_PLK_PLK1_PLK1_ST	Q8TD19	NEK9	P53350	PLK1	S76	V78L	78	Missense	proximal	2	no	12.438	12.306	EPSD	COSMIC	10.919	Down-regulation
Other_PLK_PLK1_PLK1_ST	Q8TD19	NEK9	P53350	PLK1	S206	K199N	199	Missense	distal	-7	no	13.924	14.080	EPSD	COSMIC	10.919	Up-regulation
Other_PLK_PLK1_PLK1_ST	Q8TD19	NEK9	P53350	PLK1	T250	N255S	255	Missense	distal	5	no	10.711	11.314	EPSD	COSMIC	10.919	Gain
Other_PLK_PLK1_PLK1_ST	Q8TD19	NEK9	P53350	PLK1	T662	D659E	659	Missense	distal	-3	no	12.975	12.516	EPSD	COSMIC	10.919	Down-regulation
Other_PLK_PLK1_PLK1_ST	Q8TD19	NEK9	P53350	PLK1	T662	D667A	667	Missense	distal	5	no	12.975	13.393	EPSD	COSMIC	10.919	Up-regulation
Other_PLK_PLK1_PLK1_ST	Q8TD19	NEK9	P53350	PLK1	S966	S966F	966	Missense	central	0	yes	12.166	0.000	EPSD	COSMIC	10.919	Loss
Other_PLK_PLK1_PLK1_ST	Q8TD19	NEK9	P53350	PLK1	S966	L970P	970	Missense	distal	4	no	12.166	12.456	EPSD	COSMIC;GDSC;CCLE	10.919	Up-regulation
Other_PLK_PLK1_PLK1_ST	Q13416	ORC2	P53350	PLK1	S124	L125V	125	Missense	proximal	1	no	12.397	11.998	EPSD	COSMIC	10.919	Down-regulation
Other_PLK_PLK1_PLK1_ST	Q13416	ORC2	P53350	PLK1	S124	S124R	124	Missense	central	0	yes	12.397	0.000	EPSD	COSMIC	10.919	Loss
Other_PLK_PLK1_PLK1_ST	Q13416	ORC2	P53350	PLK1	T132	L125V	125	Missense	distal	-7	no	12.926	12.934	EPSD	COSMIC	10.919	Up-regulation
Other_PLK_PLK1_PLK1_ST	Q13416	ORC2	P53350	PLK1	S156	P163S	163	Missense	distal	7	no	13.391	13.364	EPSD	COSMIC	10.919	Down-regulation
Other_PLK_PLK1_PLK1_ST	Q13416	ORC2	P53350	PLK1	S177	R174K	174	Missense	distal	-3	no	11.229	10.769	EPSD	COSMIC	10.919	Loss
Other_PLK_PLK1_PLK1_ST	Q13416	ORC2	P53350	PLK1	S179	R174K	174	Missense	distal	-5	no	11.399	10.860	EPSD	COSMIC	10.919	Loss
Other_PLK_PLK1_PLK1_ST	Q13416	ORC2	P53350	PLK1	S188	E189Q	189	Missense	proximal	1	no	12.626	12.750	PhosphoSitePlus	COSMIC	10.919	Up-regulation
Other_PLK_PLK1_PLK1_ST	Q13416	ORC2	P53350	PLK1	S282	S277R	277	Missense	distal	-5	no	10.314	10.997	EPSD	COSMIC	10.919	Gain
CMGC_CDK_CDK8_CDK19_ST	P46531	NOTCH1	Q9BWU1	CDK19	S1941	A1943V	1943	Missense	proximal	2	no	3.600	3.588	EPSD	COSMIC	1.856	Down-regulation
CMGC_CDK_CDK8_CDK19_ST	P46531	NOTCH1	Q9BWU1	CDK19	S1941	A1944T	1944	Missense	distal	3	no	3.600	3.599	EPSD	COSMIC;CCLE	1.856	Down-regulation
CMGC_CDK_CDK8_CDK19_ST	P46531	NOTCH1	Q9BWU1	CDK19	S1941	R1937C	1937	Missense	distal	-4	no	3.600	3.561	EPSD	COSMIC	1.856	Down-regulation
CMGC_CDK_CDK8_CDK19_ST	P46531	NOTCH1	Q9BWU1	CDK19	S1941	S1941F	1941	Missense	central	0	yes	3.600	0.000	EPSD	COSMIC	1.856	Loss
CMGC_CDK_CDK8_CDK19_ST	P46531	NOTCH1	Q9BWU1	CDK19	S1941	R1940C	1940	Missense	proximal	-1	no	3.600	3.559	EPSD	COSMIC	1.856	Down-regulation
CMGC_CDK_CDK8_CDK19_ST	P46531	NOTCH1	Q9BWU1	CDK19	S1941	A1935V	1935	Missense	distal	-6	no	3.600	2.649	EPSD	COSMIC	1.856	Down-regulation
CMGC_CDK_CDK8_CDK19_ST	P46531	NOTCH1	Q9BWU1	CDK19	T1997	A2002V	2002	Missense	distal	5	no	1.759	1.929	EPSD	COSMIC	1.856	Gain
CMGC_CDK_CDK8_CDK19_ST	P46531	NOTCH1	Q9BWU1	CDK19	T2090	R2087W	2087	Missense	distal	-3	no	1.816	2.085	EPSD	COSMIC	1.856	Gain
CMGC_CDK_CDK8_CDK19_ST	P46531	NOTCH1	Q9BWU1	CDK19	T2132	P2133A	2133	Missense	proximal	1	no	2.184	2.189	EPSD	COSMIC	1.856	Up-regulation
CMGC_CDK_CDK8_CDK19_ST	P46531	NOTCH1	Q9BWU1	CDK19	T2132	L2139F	2139	Missense	distal	7	no	2.184	2.153	EPSD	COSMIC	1.856	Down-regulation
CMGC_CDK_CDK8_CDK19_ST	P46531	NOTCH1	Q9BWU1	CDK19	T2132	G2131N	2131	Missense	proximal	-1	no	2.184	2.164	EPSD	COSMIC	1.856	Down-regulation
CMGC_CDK_CDK8_CDK19_ST	P46531	NOTCH1	Q9BWU1	CDK19	T2132	T2132M	2132	Missense	central	0	yes	2.184	0.000	EPSD	COSMIC	1.856	Loss
CMGC_CDK_CDK8_CDK19_ST	P46531	NOTCH1	Q9BWU1	CDK19	T2132	L2139P	2139	Missense	distal	7	no	2.184	2.215	EPSD	COSMIC	1.856	Up-regulation
CMGC_CDK_CDK8_CDK19_ST	P46531	NOTCH1	Q9BWU1	CDK19	T2132	L2129V	2129	Missense	distal	-3	no	2.184	2.173	EPSD	COSMIC	1.856	Down-regulation
CMGC_CDK_CDK8_CDK19_ST	P46531	NOTCH1	Q9BWU1	CDK19	S2513	P2508A	2508	Missense	distal	-5	no	0.608	3.351	PhosphoSitePlus;EPSD	COSMIC	1.856	Gain
CMGC_CDK_CDK8_CDK19_ST	P46531	NOTCH1	Q9BWU1	CDK19	S2521	S2516A	2516	Missense	distal	-5	no	1.402	3.471	EPSD	COSMIC	1.856	Gain
CMGC_CDK_CDK8_CDK19_ST	O00303	EIF3F	Q9BWU1	CDK19	S46	D48Y	48	Missense	proximal	2	no	7.128	7.094	PhosphoSitePlus;EPSD	COSMIC	1.856	Down-regulation
CMGC_CDK_CDK8_CDK19_ST	O00303	EIF3F	Q9BWU1	CDK19	S46	A44T	44	Missense	proximal	-2	no	7.128	7.232	PhosphoSitePlus;EPSD	COSMIC;CCLE	1.856	Up-regulation
CMGC_CDK_CDK8_CDK19_ST	O00303	EIF3F	Q9BWU1	CDK19	S46	P39L	39	Missense	distal	-7	no	7.128	7.235	PhosphoSitePlus;EPSD	COSMIC	1.856	Up-regulation
CMGC_CDK_CDK8_CDK19_ST	O00303	EIF3F	Q9BWU1	CDK19	S105	G112V	112	Missense	distal	7	no	2.988	3.193	EPSD	COSMIC	1.856	Up-regulation
CMGC_CDK_CDK8_CDK19_ST	O00303	EIF3F	Q9BWU1	CDK19	T119	G118R	118	Missense	proximal	-1	no	8.414	8.472	EPSD;PhosphoSitePlus	COSMIC	1.856	Up-regulation
CMGC_CDK_CDK8_CDK19_ST	O00303	EIF3F	Q9BWU1	CDK19	T119	G112V	112	Missense	distal	-7	no	8.414	8.336	EPSD;PhosphoSitePlus	COSMIC	1.856	Down-regulation
CMGC_CDK_CDK8_CDK19_ST	O00303	EIF3F	Q9BWU1	CDK19	T119	D125Y	125	Missense	distal	6	no	8.414	8.394	EPSD;PhosphoSitePlus	COSMIC	1.856	Down-regulation
CMGC_CDK_CDK8_CDK19_ST	O00303	EIF3F	Q9BWU1	CDK19	T119	D125N	125	Missense	distal	6	no	8.414	8.385	EPSD;PhosphoSitePlus	COSMIC	1.856	Down-regulation
CMGC_CDK_CDK8_CDK19_ST	O00303	EIF3F	Q9BWU1	CDK19	S295	A300T	300	Missense	distal	5	no	2.907	2.854	EPSD	COSMIC	1.856	Down-regulation
CMGC_CDK_CDK8_CDK19_ST	O00303	EIF3F	Q9BWU1	CDK19	S295	G296A	296	Missense	proximal	1	no	2.907	2.858	EPSD	COSMIC	1.856	Down-regulation
CMGC_CDK_CDK8_CDK19_ST	O00303	EIF3F	Q9BWU1	CDK19	S295	E291D	291	Missense	distal	-4	no	2.907	3.096	EPSD	COSMIC;GDSC;CCLE	1.856	Up-regulation
CMGC_CDK_CDK8_CDK19_ST	Q13153	PAK1	Q9BWU1	CDK19	T109	R105C	105	Missense	distal	-4	no	4.084	4.044	EPSD	COSMIC	1.856	Down-regulation
CMGC_CDK_CDK8_CDK19_ST	Q13153	PAK1	Q9BWU1	CDK19	T109	S115L	115	Missense	distal	6	no	4.084	3.875	EPSD	COSMIC;CCLE	1.856	Down-regulation
CMGC_CDK_CDK8_CDK19_ST	Q13153	PAK1	Q9BWU1	CDK19	T109	N111H	111	Missense	proximal	2	no	4.084	4.054	EPSD	COSMIC;GDSC;CCLE	1.856	Down-regulation
CMGC_CDK_CDK8_CDK19_ST	Q13153	PAK1	Q9BWU1	CDK19	T109	E116D	116	Missense	distal	7	no	4.084	4.134	EPSD	COSMIC;CCLE	1.856	Up-regulation
CMGC_CDK_CDK8_CDK19_ST	Q13153	PAK1	Q9BWU1	CDK19	T109	R105W	105	Missense	distal	-4	no	4.084	4.013	EPSD	COSMIC	1.856	Down-regulation
CMGC_CDK_CDK8_CDK19_ST	Q13153	PAK1	Q9BWU1	CDK19	S144	K141E	141	Missense	distal	-3	no	1.972	2.158	EPSD	COSMIC	1.856	Up-regulation
CMGC_CDK_CDK8_CDK19_ST	Q13153	PAK1	Q9BWU1	CDK19	S144	Y142C	142	Missense	proximal	-2	no	1.972	1.916	EPSD	COSMIC	1.856	Down-regulation
CMGC_CDK_CDK8_CDK19_ST	Q13153	PAK1	Q9BWU1	CDK19	S144	E151K	151	Missense	distal	7	no	1.972	2.011	EPSD	COSMIC	1.856	Up-regulation
CMGC_CDK_CDK8_CDK19_ST	Q13153	PAK1	Q9BWU1	CDK19	S155	S155Y	155	Missense	central	0	yes	3.249	0.000	EPSD	COSMIC	1.856	Loss
CMGC_CDK_CDK8_CDK19_ST	Q13153	PAK1	Q9BWU1	CDK19	S155	E151K	151	Missense	distal	-4	no	3.249	3.243	EPSD	COSMIC	1.856	Down-regulation
CMGC_CDK_CDK8_CDK19_ST	Q13153	PAK1	Q9BWU1	CDK19	S155	D152H	152	Missense	distal	-3	no	3.249	3.429	EPSD	COSMIC	1.856	Up-regulation
CMGC_CDK_CDK8_CDK19_ST	Q13153	PAK1	Q9BWU1	CDK19	S174	D180Y	180	Missense	distal	6	no	7.693	7.673	PhosphoSitePlus	COSMIC	1.856	Down-regulation
CMGC_CDK_CDK8_CDK19_ST	Q13153	PAK1	Q9BWU1	CDK19	S174	A169V	169	Missense	distal	-5	no	7.693	3.975	PhosphoSitePlus	COSMIC	1.856	Down-regulation
CMGC_CDK_CDK8_CDK19_ST	Q13153	PAK1	Q9BWU1	CDK19	S174	E177K	177	Missense	distal	3	no	7.693	7.737	PhosphoSitePlus	COSMIC	1.856	Up-regulation
CMGC_CDK_CDK8_CDK19_ST	Q13153	PAK1	Q9BWU1	CDK19	S223	T219A	219	Missense	distal	-4	no	1.964	1.972	EPSD	COSMIC	1.856	Up-regulation
CMGC_CDK_CDK8_CDK19_ST	Q13153	PAK1	Q9BWU1	CDK19	S223	I222V	222	Missense	proximal	-1	no	1.964	1.930	EPSD	COSMIC	1.856	Down-regulation
CMGC_CDK_CDK8_CDK19_ST	Q13153	PAK1	Q9BWU1	CDK19	S223	P221A	221	Missense	proximal	-2	no	1.964	1.819	EPSD	COSMIC	1.856	Loss
CMGC_CDK_CDK8_CDK19_ST	Q13153	PAK1	Q9BWU1	CDK19	S223	N228H	228	Missense	distal	5	no	1.964	1.994	EPSD	COSMIC	1.856	Up-regulation
CMGC_CDK_CDK8_CDK19_ST	Q13153	PAK1	Q9BWU1	CDK19	T230	R237P	237	Missense	distal	7	no	2.461	2.587	EPSD	COSMIC	1.856	Up-regulation
CMGC_CDK_CDK8_CDK19_ST	Q13153	PAK1	Q9BWU1	CDK19	T230	R237W	237	Missense	distal	7	no	2.461	2.528	EPSD	COSMIC	1.856	Up-regulation
CMGC_CDK_CDK8_CDK19_ST	Q13153	PAK1	Q9BWU1	CDK19	T230	N228H	228	Missense	proximal	-2	no	2.461	2.384	EPSD	COSMIC	1.856	Down-regulation
CMGC_CDK_CDK8_CDK19_ST	Q13153	PAK1	Q9BWU1	CDK19	T239	R237P	237	Missense	proximal	-2	no	2.761	2.675	EPSD	COSMIC	1.856	Down-regulation
CMGC_CDK_CDK8_CDK19_ST	Q13153	PAK1	Q9BWU1	CDK19	T239	K245R	245	Missense	distal	6	no	2.761	2.869	EPSD	COSMIC	1.856	Up-regulation
CMGC_CDK_CDK8_CDK19_ST	Q13153	PAK1	Q9BWU1	CDK19	T239	K243Q	243	Missense	distal	4	no	2.761	2.733	EPSD	COSMIC	1.856	Down-regulation
CMGC_CDK_CDK8_CDK19_ST	Q13153	PAK1	Q9BWU1	CDK19	T239	R237W	237	Missense	proximal	-2	no	2.761	2.711	EPSD	COSMIC	1.856	Down-regulation
CMGC_CDK_CDK8_CDK19_ST	Q13153	PAK1	Q9BWU1	CDK19	T437	R438Q	438	Missense	proximal	1	no	2.751	2.716	EPSD	COSMIC	1.856	Down-regulation
CMGC_CDK_CDK8_CDK19_ST	Q13153	PAK1	Q9BWU1	CDK19	T437	K439N	439	Missense	proximal	2	no	2.751	2.778	EPSD	COSMIC	1.856	Up-regulation
CMGC_CDK_CDK8_CDK19_ST	Q13153	PAK1	Q9BWU1	CDK19	S529	S528F	528	Missense	proximal	-1	no	1.969	1.981	EPSD	COSMIC	1.856	Up-regulation
CMGC_CDK_CDK8_CDK19_ST	Q13153	PAK1	Q9BWU1	CDK19	S529	L533M	533	Missense	distal	4	no	1.969	1.955	EPSD	COSMIC	1.856	Down-regulation
CMGC_CDK_CDK5_CDK5_ST	O60331	PIP5K1C	Q00535	CDK5	S453	G460S	460	Missense	distal	7	no	20.931	20.941	PhosphoSitePlus;EPSD	COSMIC	8.808	Up-regulation
CMGC_CDK_CDK5_CDK5_ST	O60331	PIP5K1C	Q00535	CDK5	S453	G460C	460	Missense	distal	7	no	20.931	20.926	PhosphoSitePlus;EPSD	COSMIC	8.808	Down-regulation
CMGC_CDK_CDK5_CDK5_ST	O60331	PIP5K1C	Q00535	CDK5	S453	S448F	448	Missense	distal	-5	no	20.931	20.601	PhosphoSitePlus;EPSD	COSMIC	8.808	Down-regulation
CMGC_CDK_CDK5_CDK5_ST	O60331	PIP5K1C	Q00535	CDK5	T531	S532P	532	Missense	proximal	1	no	5.540	17.441	EPSD	COSMIC;GDSC;CCLE	8.808	Gain
CMGC_CDK_CDK5_CDK5_ST	O60331	PIP5K1C	Q00535	CDK5	S539	R538L	538	Missense	proximal	-1	no	17.824	17.819	EPSD	COSMIC	8.808	Down-regulation
CMGC_CDK_CDK5_CDK5_ST	O60331	PIP5K1C	Q00535	CDK5	S539	S532P	532	Missense	distal	-7	no	17.824	17.820	EPSD	COSMIC;GDSC;CCLE	8.808	Down-regulation
CMGC_CDK_CDK5_CDK5_ST	O60331	PIP5K1C	Q00535	CDK5	S650	L652F	652	Missense	proximal	2	no	19.519	19.456	EPSD;PhosphoSitePlus	COSMIC;CCLE	8.808	Down-regulation
CMGC_CDK_CDK5_CDK5_ST	O60331	PIP5K1C	Q00535	CDK5	S650	H653P	653	Missense	distal	3	no	19.519	19.139	EPSD;PhosphoSitePlus	COSMIC	8.808	Down-regulation
CMGC_CDK_CDK5_CDK5_ST	Q07820	MCL1	Q00535	CDK5	S64	G58S	58	Missense	distal	-6	no	17.563	17.658	EPSD	COSMIC	8.808	Up-regulation
CMGC_CDK_CDK5_CDK5_ST	Q07820	MCL1	Q00535	CDK5	S64	G59E	59	Missense	distal	-5	no	17.563	17.559	EPSD	COSMIC	8.808	Down-regulation
CMGC_CDK_CDK5_CDK5_ST	Q07820	MCL1	Q00535	CDK5	S64	P65L	65	Missense	proximal	1	no	17.563	5.613	EPSD	COSMIC	8.808	Loss
CMGC_CDK_CDK5_CDK5_ST	Q07820	MCL1	Q00535	CDK5	T70	D72G	72	Missense	proximal	2	no	17.603	17.635	EPSD	COSMIC	8.808	Up-regulation
CMGC_CDK_CDK5_CDK5_ST	Q07820	MCL1	Q00535	CDK5	T70	P65L	65	Missense	distal	-5	no	17.603	17.405	EPSD	COSMIC	8.808	Down-regulation
CMGC_CDK_CDK5_CDK5_ST	Q07820	MCL1	Q00535	CDK5	T70	A77V	77	Missense	distal	7	no	17.603	17.610	EPSD	COSMIC	8.808	Up-regulation
CMGC_CDK_CDK5_CDK5_ST	Q07820	MCL1	Q00535	CDK5	S73	D72G	72	Missense	proximal	-1	no	9.263	9.262	EPSD	COSMIC	8.808	Down-regulation
CMGC_CDK_CDK5_CDK5_ST	Q07820	MCL1	Q00535	CDK5	S73	P79A	79	Missense	distal	6	no	9.263	9.251	EPSD	COSMIC	8.808	Down-regulation
CMGC_CDK_CDK5_CDK5_ST	Q07820	MCL1	Q00535	CDK5	S73	A77V	77	Missense	distal	4	no	9.263	9.305	EPSD	COSMIC	8.808	Up-regulation
CMGC_CDK_CDK5_CDK5_ST	Q07820	MCL1	Q00535	CDK5	T92	P93R	93	Missense	proximal	1	no	18.506	9.559	PhosphoSitePlus	COSMIC	8.808	Down-regulation
CMGC_CDK_CDK5_CDK5_ST	Q07820	MCL1	Q00535	CDK5	T92	F99L	99	Missense	distal	7	no	18.506	18.511	PhosphoSitePlus	COSMIC	8.808	Up-regulation
CMGC_CDK_CDK5_CDK5_ST	Q07820	MCL1	Q00535	CDK5	T92	P87L	87	Missense	distal	-5	no	18.506	18.309	PhosphoSitePlus	COSMIC	8.808	Down-regulation
CMGC_CDK_CDK5_CDK5_ST	Q07820	MCL1	Q00535	CDK5	S121	L126M	126	Missense	distal	5	no	17.010	16.991	EPSD	COSMIC	8.808	Down-regulation
CMGC_CDK_CDK5_CDK5_ST	Q07820	MCL1	Q00535	CDK5	S121	A116P	116	Missense	distal	-5	no	17.010	17.169	EPSD	COSMIC	8.808	Up-regulation
CMGC_CDK_CDK5_CDK5_ST	Q07820	MCL1	Q00535	CDK5	S121	P122L	122	Missense	proximal	1	no	17.010	5.060	EPSD	COSMIC	8.808	Loss
CMGC_CDK_CDK5_CDK5_ST	Q07820	MCL1	Q00535	CDK5	T163	E169K	169	Missense	distal	6	no	18.116	18.135	EPSD	COSMIC	8.808	Up-regulation
CMGC_CDK_CDK5_CDK5_ST	Q07820	MCL1	Q00535	CDK5	T163	P161F	161	Missense	proximal	-2	no	18.116	17.458	EPSD	COSMIC	8.808	Down-regulation
CMGC_CDK_CDK5_CDK5_ST	Q07820	MCL1	Q00535	CDK5	T163	P161H	161	Missense	proximal	-2	no	18.116	17.800	EPSD	COSMIC	8.808	Down-regulation
CMGC_CDK_CDK5_CDK5_ST	Q07820	MCL1	Q00535	CDK5	T163	G158R	158	Missense	distal	-5	no	18.116	18.368	EPSD	COSMIC	8.808	Up-regulation
CMGC_CDK_CDK5_CDK5_ST	Q07820	MCL1	Q00535	CDK5	T163	G158D	158	Missense	distal	-5	no	18.116	18.122	EPSD	COSMIC	8.808	Up-regulation
CMGC_CDK_CDK5_CDK5_ST	Q07820	MCL1	Q00535	CDK5	S206	T212A	212	Missense	distal	6	no	9.433	9.421	EPSD	COSMIC	8.808	Down-regulation
CMGC_CDK_CDK5_CDK5_ST	P49023	PXN	Q00535	CDK5	T29	P22L	22	Missense	distal	-7	no	17.285	17.234	EPSD	COSMIC	8.808	Down-regulation
CMGC_CDK_CDK5_CDK5_ST	P49023	PXN	Q00535	CDK5	T29	P22H	22	Missense	distal	-7	no	17.285	17.259	EPSD	COSMIC;GDSC;CCLE	8.808	Down-regulation
CMGC_CDK_CDK5_CDK5_ST	P49023	PXN	Q00535	CDK5	T29	P30L	30	Missense	proximal	1	no	17.285	5.336	EPSD	COSMIC	8.808	Loss
CMGC_CDK_CDK5_CDK5_ST	P49023	PXN	Q00535	CDK5	S85	S83N	83	Missense	proximal	-2	no	17.443	17.330	PhosphoSitePlus;EPSD	COSMIC	8.808	Down-regulation
CMGC_CDK_CDK5_CDK5_ST	P49023	PXN	Q00535	CDK5	S106	P107L	107	Missense	proximal	1	no	17.956	6.006	EPSD	COSMIC;GDSC	8.808	Loss
CMGC_CDK_CDK5_CDK5_ST	P49023	PXN	Q00535	CDK5	S106	P107Q	107	Missense	proximal	1	no	17.956	8.980	EPSD	COSMIC	8.808	Down-regulation
CMGC_CDK_CDK5_CDK5_ST	P49023	PXN	Q00535	CDK5	S130	V133I	133	Missense	distal	3	no	18.453	18.004	EPSD	COSMIC	8.808	Down-regulation
CMGC_CDK_CDK5_CDK5_ST	P49023	PXN	Q00535	CDK5	S130	A127T	127	Missense	distal	-3	no	18.453	18.498	EPSD	COSMIC	8.808	Up-regulation
CMGC_CDK_CDK5_CDK5_ST	P49023	PXN	Q00535	CDK5	S130	T136M	136	Missense	distal	6	no	18.453	18.436	EPSD	COSMIC	8.808	Down-regulation
CMGC_CDK_CDK5_CDK5_ST	P49023	PXN	Q00535	CDK5	S130	S126P	126	Missense	distal	-4	no	18.453	18.106	EPSD	COSMIC	8.808	Down-regulation
CMGC_CDK_CDK5_CDK5_ST	P49023	PXN	Q00535	CDK5	S170	D165Y	165	Missense	distal	-5	no	16.598	16.514	EPSD	COSMIC	8.808	Down-regulation
CMGC_CDK_CDK5_CDK5_ST	P49023	PXN	Q00535	CDK5	S170	G175W	175	Missense	distal	5	no	16.598	16.588	EPSD	COSMIC	8.808	Down-regulation
CMGC_CDK_CDK5_CDK5_ST	P49023	PXN	Q00535	CDK5	S170	P163L	163	Missense	distal	-7	no	16.598	16.546	EPSD	COSMIC	8.808	Down-regulation
CMGC_CDK_CDK5_CDK5_ST	P49023	PXN	Q00535	CDK5	S170	P172L	172	Missense	proximal	2	no	16.598	16.433	EPSD	COSMIC	8.808	Down-regulation
CMGC_CDK_CDK5_CDK5_ST	P49023	PXN	Q00535	CDK5	S170	P171S	171	Missense	proximal	1	no	16.598	4.697	EPSD	COSMIC	8.808	Loss
CMGC_CDK_CDK5_CDK5_ST	P49023	PXN	Q00535	CDK5	S170	N168I	168	Missense	proximal	-2	no	16.598	16.489	EPSD	COSMIC;GDSC	8.808	Down-regulation
CMGC_CDK_CDK5_CDK5_ST	P49023	PXN	Q00535	CDK5	S178	G175W	175	Missense	distal	-3	no	17.129	17.132	EPSD	COSMIC	8.808	Up-regulation
CMGC_CDK_CDK5_CDK5_ST	P49023	PXN	Q00535	CDK5	S178	P172L	172	Missense	distal	-6	no	17.129	17.046	EPSD	COSMIC	8.808	Down-regulation
CMGC_CDK_CDK5_CDK5_ST	P49023	PXN	Q00535	CDK5	S178	P171S	171	Missense	distal	-7	no	17.129	17.134	EPSD	COSMIC	8.808	Up-regulation
CMGC_CDK_CDK5_CDK5_ST	P49023	PXN	Q00535	CDK5	S230	P231L	231	Missense	proximal	1	no	17.745	5.795	EPSD	COSMIC;CCLE	8.808	Loss
CMGC_CDK_CDK5_CDK5_ST	P49023	PXN	Q00535	CDK5	S230	P229L	229	Missense	proximal	-1	no	17.745	17.740	EPSD	COSMIC	8.808	Down-regulation
CMGC_CDK_CDK5_CDK5_ST	P49023	PXN	Q00535	CDK5	S244	E241D	241	Missense	distal	-3	no	18.506	18.504	EPSD;PhosphoSitePlus	COSMIC	8.808	Down-regulation
CMGC_CDK_CDK5_CDK5_ST	P49023	PXN	Q00535	CDK5	S303	P304L	304	Missense	proximal	1	no	17.358	5.408	EPSD	COSMIC	8.808	Loss
CMGC_CDK_CDK5_CDK5_ST	P49023	PXN	Q00535	CDK5	S303	P304R	304	Missense	proximal	1	no	17.358	8.410	EPSD	COSMIC	8.808	Loss
CMGC_CDK_CDK5_CDK5_ST	P49023	PXN	Q00535	CDK5	S303	G300R	300	Missense	distal	-3	no	17.358	17.413	EPSD	COSMIC	8.808	Up-regulation
CMGC_CDK_CDK5_CDK5_ST	P49023	PXN	Q00535	CDK5	S303	E309K	309	Missense	distal	6	no	17.358	17.376	EPSD	COSMIC	8.808	Up-regulation
CMGC_CDK_CDK5_CDK5_ST	P49023	PXN	Q00535	CDK5	S303	D298Y	298	Missense	distal	-5	no	17.358	17.274	EPSD	COSMIC	8.808	Down-regulation
CMGC_CDK_CDK5_CDK5_ST	P49023	PXN	Q00535	CDK5	S303	S303R	303	Missense	central	0	yes	17.358	0.000	EPSD	COSMIC	8.808	Loss
CMGC_CDK_CDK5_CDK5_ST	P49023	PXN	Q00535	CDK5	S303	G306R	306	Missense	distal	3	no	17.358	18.739	EPSD	COSMIC	8.808	Up-regulation
CMGC_CDK_CDK5_CDK5_ST	P49023	PXN	Q00535	CDK5	S303	R301Q	301	Missense	proximal	-2	no	17.358	17.220	EPSD	COSMIC	8.808	Down-regulation
CMGC_CDK_CDK5_CDK5_ST	P49023	PXN	Q00535	CDK5	S303	G299S	299	Missense	distal	-4	no	17.358	18.199	EPSD	COSMIC	8.808	Up-regulation
CMGC_CDK_CDK5_CDK5_ST	P49023	PXN	Q00535	CDK5	S322	P328S	328	Missense	distal	6	no	17.843	17.844	EPSD	COSMIC	8.808	Up-regulation
CMGC_CDK_CDK5_CDK5_ST	P49023	PXN	Q00535	CDK5	S322	S322A	322	Missense	central	0	yes	17.843	0.000	EPSD	COSMIC	8.808	Loss
CMGC_CDK_CDK5_CDK5_ST	P49023	PXN	Q00535	CDK5	S332	P328S	328	Missense	distal	-4	no	8.540	8.887	EPSD	COSMIC	8.808	Gain
CMGC_CDK_CDK5_CDK5_ST	P49023	PXN	Q00535	CDK5	S414	K407E	407	Missense	distal	-7	no	16.716	16.653	EPSD	COSMIC	8.808	Down-regulation
CMGC_CDK_CDK5_CDK5_ST	P49023	PXN	Q00535	CDK5	S414	R416H	416	Missense	proximal	2	no	16.716	16.601	EPSD	COSMIC	8.808	Down-regulation
CMGC_CDK_CDK5_CDK5_ST	P49023	PXN	Q00535	CDK5	S414	F413L	413	Missense	proximal	-1	no	16.716	16.718	EPSD	COSMIC	8.808	Up-regulation
CMGC_CDK_CDK5_CDK5_ST	P10636	MAPT	Q00535	CDK5	T69	E62K	62	Missense	distal	-7	no	17.225	17.288	EPSD	COSMIC	8.808	Up-regulation
CMGC_CDK_CDK5_CDK5_ST	P10636	MAPT	Q00535	CDK5	T111	I108V	108	Missense	distal	-3	no	15.796	15.811	EPSD	COSMIC	8.808	Up-regulation
CMGC_CDK_CDK5_CDK5_ST	P10636	MAPT	Q00535	CDK5	T111	G107R	107	Missense	distal	-4	no	15.796	16.176	EPSD	COSMIC	8.808	Up-regulation
CMGC_CDK_CDK5_CDK5_ST	P10636	MAPT	Q00535	CDK5	S228	S227N	227	Missense	proximal	-1	no	17.027	17.024	EPSD	COSMIC	8.808	Down-regulation
CMGC_CDK_CDK5_CDK5_ST	P10636	MAPT	Q00535	CDK5	S228	S227I	227	Missense	proximal	-1	no	17.027	17.024	EPSD	COSMIC	8.808	Down-regulation
CMGC_CDK_CDK5_CDK5_ST	P10636	MAPT	Q00535	CDK5	S228	E226K	226	Missense	proximal	-2	no	17.027	17.440	EPSD	COSMIC	8.808	Up-regulation
CMGC_CDK_CDK5_CDK5_ST	P10636	MAPT	Q00535	CDK5	S228	Q230R	230	Missense	proximal	2	no	17.027	17.167	EPSD	COSMIC	8.808	Up-regulation
CMGC_CDK_CDK5_CDK5_ST	P10636	MAPT	Q00535	CDK5	S228	P233S	233	Missense	distal	5	no	17.027	17.040	EPSD	COSMIC	8.808	Up-regulation
CMGC_CDK_CDK5_CDK5_ST	P10636	MAPT	Q00535	CDK5	S228	D225E	225	Missense	distal	-3	no	17.027	17.030	EPSD	COSMIC	8.808	Up-regulation
CMGC_CDK_CDK5_CDK5_ST	P10636	MAPT	Q00535	CDK5	S228	S227G	227	Missense	proximal	-1	no	17.027	17.022	EPSD	COSMIC	8.808	Down-regulation
CMGC_CDK_CDK5_CDK5_ST	P10636	MAPT	Q00535	CDK5	S228	S235L	235	Missense	distal	7	no	17.027	17.015	EPSD	COSMIC	8.808	Down-regulation
CMGC_CDK_CDK5_CDK5_ST	P10636	MAPT	Q00535	CDK5	S232	S227N	227	Missense	distal	-5	no	18.084	17.992	EPSD	COSMIC	8.808	Down-regulation
CMGC_CDK_CDK5_CDK5_ST	P10636	MAPT	Q00535	CDK5	S232	S227I	227	Missense	distal	-5	no	18.084	17.952	EPSD	COSMIC	8.808	Down-regulation
CMGC_CDK_CDK5_CDK5_ST	P10636	MAPT	Q00535	CDK5	S232	A237T	237	Missense	distal	5	no	18.084	18.218	EPSD	COSMIC	8.808	Up-regulation
CMGC_CDK_CDK5_CDK5_ST	P10636	MAPT	Q00535	CDK5	S232	E226K	226	Missense	distal	-6	no	18.084	18.214	EPSD	COSMIC	8.808	Up-regulation
CMGC_CDK_CDK5_CDK5_ST	P10636	MAPT	Q00535	CDK5	S232	Q230R	230	Missense	proximal	-2	no	18.084	18.221	EPSD	COSMIC	8.808	Up-regulation
CMGC_CDK_CDK5_CDK5_ST	P10636	MAPT	Q00535	CDK5	S232	S238P	238	Missense	distal	6	no	18.084	18.083	EPSD	COSMIC	8.808	Down-regulation
CMGC_CDK_CDK5_CDK5_ST	P10636	MAPT	Q00535	CDK5	S232	P233S	233	Missense	proximal	1	no	18.084	6.183	EPSD	COSMIC	8.808	Loss
CMGC_CDK_CDK5_CDK5_ST	P10636	MAPT	Q00535	CDK5	S232	S238F	238	Missense	distal	6	no	18.084	18.064	EPSD	COSMIC	8.808	Down-regulation
CMGC_CDK_CDK5_CDK5_ST	P10636	MAPT	Q00535	CDK5	S232	D225E	225	Missense	distal	-7	no	18.084	18.082	EPSD	COSMIC	8.808	Down-regulation
CMGC_CDK_CDK5_CDK5_ST	P10636	MAPT	Q00535	CDK5	S232	S227G	227	Missense	distal	-5	no	18.084	17.913	EPSD	COSMIC	8.808	Down-regulation
CMGC_CDK_CDK5_CDK5_ST	P10636	MAPT	Q00535	CDK5	S232	S235L	235	Missense	distal	3	no	18.084	17.032	EPSD	COSMIC	8.808	Down-regulation
CMGC_CDK_CDK5_CDK5_ST	P10636	MAPT	Q00535	CDK5	S238	A237T	237	Missense	proximal	-1	no	18.116	18.121	EPSD	COSMIC	8.808	Up-regulation
CMGC_CDK_CDK5_CDK5_ST	P10636	MAPT	Q00535	CDK5	S238	A240S	240	Missense	proximal	2	no	18.116	18.211	EPSD	COSMIC	8.808	Up-regulation
CMGC_CDK_CDK5_CDK5_ST	P10636	MAPT	Q00535	CDK5	S238	D242N	242	Missense	distal	4	no	18.116	18.147	EPSD	COSMIC	8.808	Up-regulation
CMGC_CDK_CDK5_CDK5_ST	P10636	MAPT	Q00535	CDK5	S238	R244W	244	Missense	distal	6	no	18.116	18.099	EPSD	COSMIC	8.808	Down-regulation
CMGC_CDK_CDK5_CDK5_ST	P10636	MAPT	Q00535	CDK5	S238	S238P	238	Missense	central	0	yes	18.116	0.000	EPSD	COSMIC	8.808	Loss
CMGC_CDK_CDK5_CDK5_ST	P10636	MAPT	Q00535	CDK5	S238	P233S	233	Missense	distal	-5	no	18.116	18.139	EPSD	COSMIC	8.808	Up-regulation
CMGC_CDK_CDK5_CDK5_ST	P10636	MAPT	Q00535	CDK5	S238	S238F	238	Missense	central	0	yes	18.116	0.000	EPSD	COSMIC	8.808	Loss
CMGC_CDK_CDK5_CDK5_ST	P10636	MAPT	Q00535	CDK5	S238	G243D	243	Missense	distal	5	no	18.116	18.087	EPSD	COSMIC	8.808	Down-regulation
CMGC_CDK_CDK5_CDK5_ST	P10636	MAPT	Q00535	CDK5	S238	S235L	235	Missense	distal	-3	no	18.116	18.061	EPSD	COSMIC	8.808	Down-regulation
CMGC_CDK_CDK5_CDK5_ST	P10636	MAPT	Q00535	CDK5	S388	G385V	385	Missense	distal	-3	no	8.857	8.889	EPSD	COSMIC	8.808	Up-regulation
CMGC_CDK_CDK5_CDK5_ST	P10636	MAPT	Q00535	CDK5	S388	T386I	386	Missense	proximal	-2	no	8.857	8.675	EPSD	COSMIC	8.808	Loss
CMGC_CDK_CDK5_CDK5_ST	P10636	MAPT	Q00535	CDK5	S388	D389N	389	Missense	proximal	1	no	8.857	10.324	EPSD	COSMIC;GDSC;CCLE	8.808	Up-regulation
CMGC_CDK_CDK5_CDK5_ST	P10636	MAPT	Q00535	CDK5	S411	L410F	410	Missense	proximal	-1	no	17.541	17.539	EPSD	COSMIC	8.808	Down-regulation
CMGC_CDK_CDK5_CDK5_ST	P10636	MAPT	Q00535	CDK5	S411	P412S	412	Missense	proximal	1	no	17.541	5.640	EPSD	COSMIC	8.808	Loss
CMGC_CDK_CDK5_CDK5_ST	P10636	MAPT	Q00535	CDK5	T416	L410F	410	Missense	distal	-6	no	16.940	16.889	EPSD	COSMIC	8.808	Down-regulation
CMGC_CDK_CDK5_CDK5_ST	P10636	MAPT	Q00535	CDK5	T416	P412S	412	Missense	distal	-4	no	16.940	17.286	EPSD	COSMIC	8.808	Up-regulation
CMGC_CDK_CDK5_CDK5_ST	P10636	MAPT	Q00535	CDK5	S438	S443Y	443	Missense	distal	5	no	17.434	17.257	EPSD	COSMIC	8.808	Down-regulation
CMGC_CDK_CDK5_CDK5_ST	P10636	MAPT	Q00535	CDK5	S447	S443Y	443	Missense	distal	-4	no	9.502	8.521	EPSD	COSMIC	8.808	Loss
CMGC_CDK_CDK5_CDK5_ST	P10636	MAPT	Q00535	CDK5	S447	S447P	447	Missense	central	0	yes	9.502	0.000	EPSD	COSMIC	8.808	Loss
CMGC_CDK_CDK5_CDK5_ST	P10636	MAPT	Q00535	CDK5	S447	R448Q	448	Missense	proximal	1	no	9.502	9.473	EPSD	COSMIC	8.808	Down-regulation
CMGC_CDK_CDK5_CDK5_ST	P10636	MAPT	Q00535	CDK5	T470	T466M	466	Missense	distal	-4	no	16.586	16.018	EPSD	COSMIC;GDSC;CCLE	8.808	Down-regulation
CMGC_CDK_CDK5_CDK5_ST	P10636	MAPT	Q00535	CDK5	T470	K467T	467	Missense	distal	-3	no	16.586	16.550	EPSD	COSMIC	8.808	Down-regulation
CMGC_CDK_CDK5_CDK5_ST	P10636	MAPT	Q00535	CDK5	T470	P477L	477	Missense	distal	7	no	16.586	16.574	EPSD	COSMIC	8.808	Down-regulation
CMGC_CDK_CDK5_CDK5_ST	P10636	MAPT	Q00535	CDK5	T492	R487K	487	Missense	distal	-5	no	17.424	17.459	EPSD	COSMIC	8.808	Up-regulation
CMGC_CDK_CDK5_CDK5_ST	P10636	MAPT	Q00535	CDK5	T492	K491R	491	Missense	proximal	-1	no	17.424	17.422	EPSD	COSMIC	8.808	Down-regulation
CMGC_CDK_CDK5_CDK5_ST	P10636	MAPT	Q00535	CDK5	T492	R487G	487	Missense	distal	-5	no	17.424	17.173	EPSD	COSMIC	8.808	Down-regulation
CMGC_CDK_CDK5_CDK5_ST	P10636	MAPT	Q00535	CDK5	T492	A495T	495	Missense	distal	3	no	17.424	18.205	EPSD	COSMIC	8.808	Up-regulation
CMGC_CDK_CDK5_CDK5_ST	P10636	MAPT	Q00535	CDK5	T492	P493L	493	Missense	proximal	1	no	17.424	5.474	EPSD	COSMIC	8.808	Loss
CMGC_CDK_CDK5_CDK5_ST	P10636	MAPT	Q00535	CDK5	T498	K491R	491	Missense	distal	-7	no	17.938	17.921	EPSD	COSMIC	8.808	Down-regulation
CMGC_CDK_CDK5_CDK5_ST	P10636	MAPT	Q00535	CDK5	T498	A495T	495	Missense	distal	-3	no	17.938	17.983	EPSD	COSMIC	8.808	Up-regulation
CMGC_CDK_CDK5_CDK5_ST	P10636	MAPT	Q00535	CDK5	T498	P493L	493	Missense	distal	-5	no	17.938	17.741	EPSD	COSMIC	8.808	Down-regulation
CMGC_CDK_CDK5_CDK5_ST	P10636	MAPT	Q00535	CDK5	S516	G521V	521	Missense	distal	5	no	17.498	17.564	EPSD	COSMIC	8.808	Up-regulation
CMGC_CDK_CDK5_CDK5_ST	P10636	MAPT	Q00535	CDK5	S516	G518V	518	Missense	proximal	2	no	17.498	17.558	EPSD	COSMIC	8.808	Up-regulation
CMGC_CDK_CDK5_CDK5_ST	P10636	MAPT	Q00535	CDK5	S516	R511C	511	Missense	distal	-5	no	17.498	17.144	EPSD	COSMIC;CCLE	8.808	Down-regulation
CMGC_CDK_CDK5_CDK5_ST	P10636	MAPT	Q00535	CDK5	S516	G509V	509	Missense	distal	-7	no	17.498	17.532	EPSD	COSMIC	8.808	Up-regulation
CMGC_CDK_CDK5_CDK5_ST	P10636	MAPT	Q00535	CDK5	S519	G521V	521	Missense	proximal	2	no	17.944	18.004	EPSD	COSMIC	8.808	Up-regulation
CMGC_CDK_CDK5_CDK5_ST	P10636	MAPT	Q00535	CDK5	S519	R526H	526	Missense	distal	7	no	17.944	17.937	EPSD	COSMIC	8.808	Down-regulation
CMGC_CDK_CDK5_CDK5_ST	P10636	MAPT	Q00535	CDK5	S519	G518V	518	Missense	proximal	-1	no	17.944	17.946	EPSD	COSMIC	8.808	Up-regulation
CMGC_CDK_CDK5_CDK5_ST	P10636	MAPT	Q00535	CDK5	T522	G521V	521	Missense	proximal	-1	no	16.384	16.387	EPSD	COSMIC	8.808	Up-regulation
CMGC_CDK_CDK5_CDK5_ST	P10636	MAPT	Q00535	CDK5	T522	R526H	526	Missense	distal	4	no	16.384	16.345	EPSD	COSMIC	8.808	Down-regulation
CMGC_CDK_CDK5_CDK5_ST	P10636	MAPT	Q00535	CDK5	T522	G518V	518	Missense	distal	-4	no	16.384	16.743	EPSD	COSMIC	8.808	Up-regulation
CMGC_CDK_CDK5_CDK5_ST	P10636	MAPT	Q00535	CDK5	T522	R528S	528	Missense	distal	6	no	16.384	16.377	EPSD	COSMIC	8.808	Down-regulation
CMGC_CDK_CDK5_CDK5_ST	P10636	MAPT	Q00535	CDK5	S525	G521V	521	Missense	distal	-4	no	9.794	10.153	EPSD	COSMIC	8.808	Up-regulation
CMGC_CDK_CDK5_CDK5_ST	P10636	MAPT	Q00535	CDK5	S525	R526H	526	Missense	proximal	1	no	9.794	0.229	EPSD	COSMIC	8.808	Loss
CMGC_CDK_CDK5_CDK5_ST	P10636	MAPT	Q00535	CDK5	S525	G518V	518	Missense	distal	-7	no	9.794	9.828	EPSD	COSMIC	8.808	Up-regulation
CMGC_CDK_CDK5_CDK5_ST	P10636	MAPT	Q00535	CDK5	S525	R528S	528	Missense	distal	3	no	9.794	8.375	EPSD	COSMIC	8.808	Loss
CMGC_CDK_CDK5_CDK5_ST	P10636	MAPT	Q00535	CDK5	S525	P530S	530	Missense	distal	5	no	9.794	9.806	EPSD	COSMIC	8.808	Up-regulation
CMGC_CDK_CDK5_CDK5_ST	P10636	MAPT	Q00535	CDK5	T529	R526H	526	Missense	distal	-3	no	16.130	16.099	EPSD	COSMIC	8.808	Down-regulation
CMGC_CDK_CDK5_CDK5_ST	P10636	MAPT	Q00535	CDK5	T529	R528S	528	Missense	proximal	-1	no	16.130	16.131	EPSD	COSMIC	8.808	Up-regulation
CMGC_CDK_CDK5_CDK5_ST	P10636	MAPT	Q00535	CDK5	T529	P530S	530	Missense	proximal	1	no	16.130	4.229	EPSD	COSMIC	8.808	Loss
CMGC_CDK_CDK5_CDK5_ST	P10636	MAPT	Q00535	CDK5	T529	P536H	536	Missense	distal	7	no	16.130	16.126	EPSD	COSMIC	8.808	Down-regulation
CMGC_CDK_CDK5_CDK5_ST	P10636	MAPT	Q00535	CDK5	T529	P535Q	535	Missense	distal	6	no	16.130	16.127	EPSD	COSMIC	8.808	Down-regulation
CMGC_CDK_CDK5_CDK5_ST	P10636	MAPT	Q00535	CDK5	T534	R528S	528	Missense	distal	-6	no	17.441	17.434	EPSD	COSMIC	8.808	Down-regulation
CMGC_CDK_CDK5_CDK5_ST	P10636	MAPT	Q00535	CDK5	T534	P530S	530	Missense	distal	-4	no	17.441	17.787	EPSD	COSMIC	8.808	Up-regulation
CMGC_CDK_CDK5_CDK5_ST	P10636	MAPT	Q00535	CDK5	T534	P536H	536	Missense	proximal	2	no	17.441	17.408	EPSD	COSMIC	8.808	Down-regulation
CMGC_CDK_CDK5_CDK5_ST	P10636	MAPT	Q00535	CDK5	T534	P535Q	535	Missense	proximal	1	no	17.441	8.465	EPSD	COSMIC	8.808	Loss
CMGC_CDK_CDK5_CDK5_ST	P10636	MAPT	Q00535	CDK5	T534	E539Q	539	Missense	distal	5	no	17.441	17.492	EPSD	COSMIC	8.808	Up-regulation
CMGC_CDK_CDK5_CDK5_ST	P10636	MAPT	Q00535	CDK5	T548	P550S	550	Missense	proximal	2	no	18.735	18.718	EPSD	COSMIC	8.808	Down-regulation
CMGC_CDK_CDK5_CDK5_ST	P10636	MAPT	Q00535	CDK5	T548	P553R	553	Missense	distal	5	no	18.735	18.811	EPSD	COSMIC	8.808	Up-regulation
CMGC_CDK_CDK5_CDK5_ST	P10636	MAPT	Q00535	CDK5	T548	P553L	553	Missense	distal	5	no	18.735	18.563	EPSD	COSMIC	8.808	Down-regulation
CMGC_CDK_CDK5_CDK5_ST	P10636	MAPT	Q00535	CDK5	T548	P549L	549	Missense	proximal	1	no	18.735	6.786	EPSD	COSMIC	8.808	Loss
CMGC_CDK_CDK5_CDK5_ST	P10636	MAPT	Q00535	CDK5	T548	S555F	555	Missense	distal	7	no	18.735	18.718	EPSD	COSMIC	8.808	Down-regulation
CMGC_CDK_CDK5_CDK5_ST	P10636	MAPT	Q00535	CDK5	T548	P553Q	553	Missense	distal	5	no	18.735	18.686	EPSD	COSMIC	8.808	Down-regulation
CMGC_CDK_CDK5_CDK5_ST	P10636	MAPT	Q00535	CDK5	S552	P550S	550	Missense	proximal	-2	no	17.986	17.887	EPSD	COSMIC	8.808	Down-regulation
CMGC_CDK_CDK5_CDK5_ST	P10636	MAPT	Q00535	CDK5	S552	R559C	559	Missense	distal	7	no	17.986	17.969	EPSD	COSMIC	8.808	Down-regulation
CMGC_CDK_CDK5_CDK5_ST	P10636	MAPT	Q00535	CDK5	S552	P553R	553	Missense	proximal	1	no	17.986	9.039	EPSD	COSMIC	8.808	Down-regulation
CMGC_CDK_CDK5_CDK5_ST	P10636	MAPT	Q00535	CDK5	S552	P553L	553	Missense	proximal	1	no	17.986	6.036	EPSD	COSMIC	8.808	Loss
CMGC_CDK_CDK5_CDK5_ST	P10636	MAPT	Q00535	CDK5	S552	P549L	549	Missense	distal	-3	no	17.986	17.925	EPSD	COSMIC	8.808	Down-regulation
CMGC_CDK_CDK5_CDK5_ST	P10636	MAPT	Q00535	CDK5	S552	S555F	555	Missense	distal	3	no	17.986	16.808	EPSD	COSMIC	8.808	Down-regulation
CMGC_CDK_CDK5_CDK5_ST	P10636	MAPT	Q00535	CDK5	S552	P553Q	553	Missense	proximal	1	no	17.986	9.010	EPSD	COSMIC	8.808	Down-regulation
CMGC_CDK_CDK5_CDK5_ST	P10636	MAPT	Q00535	CDK5	S673	L674Q	674	Missense	proximal	1	no	6.021	8.995	EPSD	COSMIC	8.808	Gain
CMGC_CDK_CDK5_CDK5_ST	P10636	MAPT	Q00535	CDK5	S713	E708D	708	Missense	distal	-5	no	17.353	17.362	EPSD	COSMIC	8.808	Up-regulation
CMGC_CDK_CDK5_CDK5_ST	P10636	MAPT	Q00535	CDK5	S713	G706R	706	Missense	distal	-7	no	17.353	17.405	EPSD	COSMIC	8.808	Up-regulation
CMGC_CDK_CDK5_CDK5_ST	P10636	MAPT	Q00535	CDK5	S713	V710M	710	Missense	distal	-3	no	17.353	17.297	EPSD	COSMIC	8.808	Down-regulation
CMGC_CDK_CDK5_CDK5_ST	P10636	MAPT	Q00535	CDK5	S713	E708K	708	Missense	distal	-5	no	17.353	17.643	EPSD	COSMIC	8.808	Up-regulation
CMGC_CDK_CDK5_CDK5_ST	P10636	MAPT	Q00535	CDK5	S713	V710A	710	Missense	distal	-3	no	17.353	17.314	EPSD	COSMIC	8.808	Down-regulation
CMGC_CDK_CDK5_CDK5_ST	P10636	MAPT	Q00535	CDK5	S721	R723W	723	Missense	proximal	2	no	18.875	18.683	EPSD	COSMIC	8.808	Down-regulation
CMGC_CDK_CDK5_CDK5_ST	P10636	MAPT	Q00535	CDK5	S721	V728M	728	Missense	distal	7	no	18.875	18.863	EPSD	COSMIC	8.808	Down-regulation
CMGC_CDK_CDK5_CDK5_ST	P10636	MAPT	Q00535	CDK5	S721	V728A	728	Missense	distal	7	no	18.875	18.867	EPSD	COSMIC	8.808	Down-regulation
CMGC_CDK_CDK5_CDK5_ST	P10636	MAPT	Q00535	CDK5	S726	G732S	732	Missense	distal	6	no	9.203	9.213	EPSD	COSMIC	8.808	Up-regulation
CMGC_CDK_CDK5_CDK5_ST	P10636	MAPT	Q00535	CDK5	S726	G732C	732	Missense	distal	6	no	9.203	9.196	EPSD	COSMIC	8.808	Down-regulation
CMGC_CDK_CDK5_CDK5_ST	P10636	MAPT	Q00535	CDK5	S726	R723W	723	Missense	distal	-3	no	9.203	9.149	EPSD	COSMIC	8.808	Down-regulation
CMGC_CDK_CDK5_CDK5_ST	P10636	MAPT	Q00535	CDK5	S726	V728M	728	Missense	proximal	2	no	9.203	9.043	EPSD	COSMIC	8.808	Down-regulation
CMGC_CDK_CDK5_CDK5_ST	P10636	MAPT	Q00535	CDK5	S726	V728A	728	Missense	proximal	2	no	9.203	9.122	EPSD	COSMIC	8.808	Down-regulation
CMGC_CDK_CDK5_CDK5_ST	P10636	MAPT	Q00535	CDK5	S739	G732S	732	Missense	distal	-7	no	17.183	17.235	EPSD	COSMIC	8.808	Up-regulation
CMGC_CDK_CDK5_CDK5_ST	P10636	MAPT	Q00535	CDK5	S739	D735N	735	Missense	distal	-4	no	17.183	17.346	EPSD	COSMIC	8.808	Up-regulation
CMGC_CDK_CDK5_CDK5_ST	P10636	MAPT	Q00535	CDK5	S739	G732C	732	Missense	distal	-7	no	17.183	17.163	EPSD	COSMIC	8.808	Down-regulation
CMGC_CDK_CDK5_CDK5_ST	P10636	MAPT	Q00535	CDK5	S739	T744M	744	Missense	distal	5	no	17.183	16.979	EPSD	COSMIC	8.808	Down-regulation
CMGC_CDK_CDK5_CDK5_ST	P10636	MAPT	Q00535	CDK5	S739	A743T	743	Missense	distal	4	no	17.183	17.242	EPSD	COSMIC	8.808	Up-regulation
CMGC_CDK_CDK5_CDK5_ST	P42858	HTT	Q00535	CDK5	S415	E409K	409	Missense	distal	-6	no	8.731	8.860	EPSD	COSMIC	8.808	Gain
CMGC_CDK_CDK5_CDK5_ST	P42858	HTT	Q00535	CDK5	T486	S489L	489	Missense	distal	3	no	17.017	15.965	EPSD	COSMIC;GDSC;CCLE	8.808	Down-regulation
CMGC_CDK_CDK5_CDK5_ST	P42858	HTT	Q00535	CDK5	S781	S781N	781	Missense	central	0	yes	9.806	0.000	EPSD	COSMIC;GDSC;CCLE	8.808	Loss
CMGC_CDK_CDK5_CDK5_ST	P42858	HTT	Q00535	CDK5	S1104	L1105P	1105	Missense	proximal	1	no	6.959	18.909	EPSD	COSMIC	8.808	Gain
CMGC_CDK_CDK5_CDK5_ST	P42858	HTT	Q00535	CDK5	S1177	L1178P	1178	Missense	proximal	1	no	6.467	18.417	EPSD	COSMIC	8.808	Gain
CMGC_CDK_CDK5_CDK5_ST	P42858	HTT	Q00535	CDK5	S1179	L1178P	1178	Missense	proximal	-1	no	19.777	19.782	EPSD;PhosphoSitePlus	COSMIC	8.808	Up-regulation
CMGC_CDK_CDK5_CDK5_ST	P42858	HTT	Q00535	CDK5	S1179	T1173A	1173	Missense	distal	-6	no	19.777	19.691	EPSD;PhosphoSitePlus	COSMIC	8.808	Down-regulation
CMGC_CDK_CDK5_CDK5_ST	P42858	HTT	Q00535	CDK5	S1179	K1186N	1186	Missense	distal	7	no	19.777	19.766	EPSD;PhosphoSitePlus	COSMIC	8.808	Down-regulation
CMGC_CDK_CDK5_CDK5_ST	P42858	HTT	Q00535	CDK5	S1199	S1199C	1199	Missense	central	0	yes	20.034	0.000	PhosphoSitePlus;EPSD	COSMIC	8.808	Loss
CMGC_CDK_CDK5_CDK5_ST	P42858	HTT	Q00535	CDK5	S1199	A1206V	1206	Missense	distal	7	no	20.034	20.042	PhosphoSitePlus;EPSD	COSMIC	8.808	Up-regulation
CMGC_CDK_CDK5_CDK5_ST	P42858	HTT	Q00535	CDK5	S1199	E1192K	1192	Missense	distal	-7	no	20.034	20.097	PhosphoSitePlus;EPSD	COSMIC	8.808	Up-regulation
CMGC_CDK_CDK5_CDK5_ST	P42858	HTT	Q00535	CDK5	T1220	T1215I	1215	Missense	distal	-5	no	9.660	9.554	EPSD	COSMIC	8.808	Down-regulation
CMGC_CDK_CDK5_CDK5_ST	P42858	HTT	Q00535	CDK5	T1220	G1217V	1217	Missense	distal	-3	no	9.660	9.693	EPSD	COSMIC	8.808	Up-regulation
CMGC_CDK_CDK5_CDK5_ST	P42858	HTT	Q00535	CDK5	S2074	P2081L	2081	Missense	distal	7	no	18.577	18.565	EPSD	COSMIC;GDSC	8.808	Down-regulation
CMGC_CDK_CDK5_CDK5_ST	P42858	HTT	Q00535	CDK5	S2074	H2080P	2080	Missense	distal	6	no	18.577	18.580	EPSD	COSMIC	8.808	Up-regulation
CMGC_CDK_CDK5_CDK5_ST	P42858	HTT	Q00535	CDK5	S2079	H2080P	2080	Missense	proximal	1	no	-0.987	17.525	EPSD	COSMIC	8.808	Gain
CMGC_CDK_CDK5_CDK5_ST	P42858	HTT	Q00535	CDK5	S2094	D2096G	2096	Missense	proximal	2	no	19.112	19.144	EPSD	COSMIC	8.808	Up-regulation
CMGC_CDK_CDK5_CDK5_ST	P42858	HTT	Q00535	CDK5	S2584	T2588K	2588	Missense	distal	4	no	18.284	18.350	EPSD	COSMIC	8.808	Up-regulation
CMGC_CDK_CDK5_CDK5_ST	P42858	HTT	Q00535	CDK5	S2584	P2585S	2585	Missense	proximal	1	no	18.284	6.383	EPSD	COSMIC	8.808	Loss
CMGC_CDK_CDK5_CDK5_ST	P42858	HTT	Q00535	CDK5	S2651	D2645N	2645	Missense	distal	-6	no	18.695	18.734	EPSD	COSMIC	8.808	Up-regulation
CMGC_CDK_CDK5_CDK5_ST	P42858	HTT	Q00535	CDK5	S2659	G2665R	2665	Missense	distal	6	no	10.320	10.337	EPSD	COSMIC	8.808	Up-regulation
CMGC_CDK_CDK5_CDK5_ST	P42858	HTT	Q00535	CDK5	S2812	N2813K	2813	Missense	proximal	1	no	10.851	1.912	EPSD	COSMIC	8.808	Loss
CMGC_CDK_CDK5_CDK5_ST	P42858	HTT	Q00535	CDK5	S2812	Y2809C	2809	Missense	distal	-3	no	10.851	10.845	EPSD	COSMIC	8.808	Down-regulation
CMGC_CDK_CDK5_CDK5_ST	P42858	HTT	Q00535	CDK5	S2934	R2937K	2937	Missense	distal	3	no	19.397	19.717	EPSD	COSMIC	8.808	Up-regulation
CMGC_CDK_CDK5_CDK5_ST	P42858	HTT	Q00535	CDK5	S2934	S2939L	2939	Missense	distal	5	no	19.397	19.212	EPSD	COSMIC;GDSC;CCLE	8.808	Down-regulation
CMGC_CDK_CDK5_CDK5_ST	P42858	HTT	Q00535	CDK5	S2934	R2937G	2937	Missense	distal	3	no	19.397	18.015	EPSD	COSMIC	8.808	Down-regulation
CMGC_CDK_CDK5_CDK5_ST	P04150	NR3C1	Q00535	CDK5	T8	R11I	11	Missense	distal	3	no	20.388	18.548	EPSD	COSMIC;GDSC;CCLE	8.808	Down-regulation
CMGC_CDK_CDK5_CDK5_ST	P04150	NR3C1	Q00535	CDK5	T8	P15L	15	Missense	distal	7	no	20.388	20.376	EPSD	COSMIC	8.808	Down-regulation
CMGC_CDK_CDK5_CDK5_ST	P04150	NR3C1	Q00535	CDK5	S45	A49V	49	Missense	distal	4	no	16.971	17.013	EPSD	COSMIC	8.808	Up-regulation
CMGC_CDK_CDK5_CDK5_ST	P04150	NR3C1	Q00535	CDK5	S52	A49V	49	Missense	distal	-3	no	8.918	8.956	EPSD	COSMIC	8.808	Up-regulation
CMGC_CDK_CDK5_CDK5_ST	P04150	NR3C1	Q00535	CDK5	S54	A49V	49	Missense	distal	-5	no	9.403	9.528	EPSD	COSMIC	8.808	Up-regulation
CMGC_CDK_CDK5_CDK5_ST	P04150	NR3C1	Q00535	CDK5	S203	T208A	208	Missense	distal	5	no	18.784	18.650	PhosphoSitePlus;EPSD	COSMIC	8.808	Down-regulation
CMGC_CDK_CDK5_CDK5_ST	P04150	NR3C1	Q00535	CDK5	S211	T208A	208	Missense	distal	-3	no	19.649	19.604	EPSD;PhosphoSitePlus	COSMIC	8.808	Down-regulation
CMGC_CDK_CDK5_CDK5_ST	P04150	NR3C1	Q00535	CDK5	S267	P268L	268	Missense	proximal	1	no	17.611	5.661	EPSD	COSMIC	8.808	Loss
CMGC_CDK_CDK5_CDK5_ST	P04150	NR3C1	Q00535	CDK5	S269	P268L	268	Missense	proximal	-1	no	9.230	9.225	EPSD	COSMIC	8.808	Down-regulation
CMGC_CDK_CDK5_CDK5_ST	P04150	NR3C1	Q00535	CDK5	T288	E285K	285	Missense	distal	-3	no	16.898	16.970	EPSD	COSMIC	8.808	Up-regulation
CMGC_CDK_CDK5_CDK5_ST	P04150	NR3C1	Q00535	CDK5	S390	Y393H	393	Missense	distal	3	no	8.002	9.169	EPSD	COSMIC	8.808	Gain
CMGC_CDK_CDK5_CDK5_ST	P04150	NR3C1	Q00535	CDK5	S395	Y393H	393	Missense	proximal	-2	no	16.926	17.139	EPSD	COSMIC	8.808	Up-regulation
CMGC_CDK_CDK5_CDK5_ST	P04150	NR3C1	Q00535	CDK5	S404	P405T	405	Missense	proximal	1	no	18.779	8.292	EPSD	COSMIC	8.808	Loss
CMGC_CDK_CDK5_CDK5_ST	P04150	NR3C1	Q00535	CDK5	S410	G415V	415	Missense	distal	5	no	9.188	9.254	EPSD	COSMIC	8.808	Up-regulation
CMGC_CDK_CDK5_CDK5_ST	P04150	NR3C1	Q00535	CDK5	S410	P405T	405	Missense	distal	-5	no	9.188	9.185	EPSD	COSMIC	8.808	Down-regulation
CMGC_CDK_CDK5_CDK5_ST	Q8NEB9	PIK3C3	Q00535	CDK5	T159	E155K	155	Missense	distal	-4	no	19.273	19.775	EPSD;PhosphoSitePlus	COSMIC	8.808	Up-regulation
CMGC_CDK_CDK5_CDK5_ST	Q8NEB9	PIK3C3	Q00535	CDK5	T159	S154L	154	Missense	distal	-5	no	19.273	19.053	EPSD;PhosphoSitePlus	COSMIC	8.808	Down-regulation
CMGC_CDK_CDK5_CDK5_ST	Q8NEB9	PIK3C3	Q00535	CDK5	T159	P160F	160	Missense	proximal	1	no	19.273	-2.707	EPSD;PhosphoSitePlus	COSMIC	8.808	Loss
CMGC_CDK_CDK5_CDK5_ST	Q8NEB9	PIK3C3	Q00535	CDK5	T159	P160A	160	Missense	proximal	1	no	19.273	8.246	EPSD;PhosphoSitePlus	COSMIC	8.808	Loss
CMGC_CDK_CDK5_CDK5_ST	Q8NEB9	PIK3C3	Q00535	CDK5	S244	F250C	250	Missense	distal	6	no	16.661	16.665	EPSD	COSMIC	8.808	Up-regulation
CMGC_CDK_CDK5_CDK5_ST	Q8NEB9	PIK3C3	Q00535	CDK5	S244	S244F	244	Missense	central	0	yes	16.661	0.000	EPSD	COSMIC	8.808	Loss
CMGC_CDK_CDK5_CDK5_ST	Q8NEB9	PIK3C3	Q00535	CDK5	T324	E327K	327	Missense	distal	3	no	6.587	8.874	EPSD	COSMIC	8.808	Gain
CMGC_CDK_CDK5_CDK5_ST	Q8NEB9	PIK3C3	Q00535	CDK5	S448	T447S	447	Missense	proximal	-1	no	17.073	17.075	EPSD	COSMIC	8.808	Up-regulation
CMGC_CDK_CDK5_CDK5_ST	Q8NEB9	PIK3C3	Q00535	CDK5	S448	S455L	455	Missense	distal	7	no	17.073	17.061	EPSD	COSMIC	8.808	Down-regulation
CMGC_CDK_CDK5_CDK5_ST	Q8NEB9	PIK3C3	Q00535	CDK5	S448	S442C	442	Missense	distal	-6	no	17.073	16.927	EPSD	COSMIC	8.808	Down-regulation
CMGC_CDK_CDK5_CDK5_ST	Q8NEB9	PIK3C3	Q00535	CDK5	S448	D441V	441	Missense	distal	-7	no	17.073	17.099	EPSD	COSMIC;GDSC;CCLE	8.808	Up-regulation
CMGC_CDK_CDK5_CDK5_ST	Q8NEB9	PIK3C3	Q00535	CDK5	S455	S455L	455	Missense	central	0	yes	18.397	0.000	EPSD	COSMIC	8.808	Loss
CMGC_CDK_CDK5_CDK5_ST	Q8NEB9	PIK3C3	Q00535	CDK5	T668	D664N	664	Missense	distal	-4	no	18.639	18.803	PhosphoSitePlus;EPSD	COSMIC	8.808	Up-regulation
CMGC_CDK_CDK5_CDK5_ST	Q8NEB9	PIK3C3	Q00535	CDK5	T668	Y670C	670	Missense	proximal	2	no	18.639	18.623	PhosphoSitePlus;EPSD	COSMIC;GDSC;CCLE	8.808	Down-regulation
CMGC_CDK_CDK5_CDK5_ST	P56817	BACE1	Q00535	CDK5	T252	G247C	247	Missense	distal	-5	no	19.204	19.102	PhosphoSitePlus	COSMIC;GDSC;CCLE	8.808	Down-regulation
CMGC_CDK_CDK5_CDK5_ST	P56817	BACE1	Q00535	CDK5	T252	P253S	253	Missense	proximal	1	no	19.204	7.303	PhosphoSitePlus	COSMIC	8.808	Loss
CMGC_CDK_CDK5_CDK5_ST	P56817	BACE1	Q00535	CDK5	T252	E257Q	257	Missense	distal	5	no	19.204	19.255	PhosphoSitePlus	COSMIC	8.808	Up-regulation
CMGC_CDK_CDK5_CDK5_ST	P56817	BACE1	Q00535	CDK5	T252	R255W	255	Missense	distal	3	no	19.204	17.514	PhosphoSitePlus	COSMIC	8.808	Down-regulation
CMGC_CDK_CDK5_CDK5_ST	P56817	BACE1	Q00535	CDK5	T252	R256G	256	Missense	distal	4	no	19.204	19.137	PhosphoSitePlus	COSMIC	8.808	Down-regulation
CMGC_CDK_CDK5_CDK5_ST	P56817	BACE1	Q00535	CDK5	T252	R256Q	256	Missense	distal	4	no	19.204	19.158	PhosphoSitePlus	COSMIC	8.808	Down-regulation
CMGC_CDK_CDK5_CDK5_ST	P56817	BACE1	Q00535	CDK5	T252	G247D	247	Missense	distal	-5	no	19.204	19.210	PhosphoSitePlus	COSMIC	8.808	Up-regulation
CMGC_CDK_CDK5_CDK5_ST	P56817	BACE1	Q00535	CDK5	T252	T246M	246	Missense	distal	-6	no	19.204	19.083	PhosphoSitePlus	COSMIC	8.808	Down-regulation
CMGC_CDK_CDK5_CDK5_ST	P56817	BACE1	Q00535	CDK5	T293	G291D	291	Missense	proximal	-2	no	8.698	8.828	EPSD	COSMIC	8.808	Gain
CMGC_CDK_CDK5_CDK5_ST	P05067	APP	Q00535	CDK5	T278	E281K	281	Missense	distal	3	no	6.835	9.122	EPSD	COSMIC	8.808	Gain
CMGC_CDK_CDK5_CDK5_ST	P05067	APP	Q00535	CDK5	T381	E380Q	380	Missense	proximal	-1	no	16.419	16.421	EPSD	COSMIC	8.808	Up-regulation
CMGC_CDK_CDK5_CDK5_ST	P05067	APP	Q00535	CDK5	T381	K377R	377	Missense	distal	-4	no	16.419	16.083	EPSD	COSMIC	8.808	Down-regulation
CMGC_CDK_CDK5_CDK5_ST	P05067	APP	Q00535	CDK5	T381	D376G	376	Missense	distal	-5	no	16.419	16.414	EPSD	COSMIC	8.808	Down-regulation
CMGC_CDK_CDK5_CDK5_ST	P05067	APP	Q00535	CDK5	T381	G383W	383	Missense	proximal	2	no	16.419	16.400	EPSD	COSMIC	8.808	Down-regulation
CMGC_CDK_CDK5_CDK5_ST	P05067	APP	Q00535	CDK5	T381	V375I	375	Missense	distal	-6	no	16.419	16.391	EPSD	COSMIC	8.808	Down-regulation
CMGC_CDK_CDK5_CDK5_ST	P05067	APP	Q00535	CDK5	T381	N386S	386	Missense	distal	5	no	16.419	16.484	EPSD	COSMIC	8.808	Up-regulation
CMGC_CDK_CDK5_CDK5_ST	P05067	APP	Q00535	CDK5	T743	V742L	742	Missense	proximal	-1	no	16.502	16.498	EPSD	COSMIC	8.808	Down-regulation
CMGC_CDK_CDK5_CDK5_ST	P05067	APP	Q00535	CDK5	T743	E745K	745	Missense	proximal	2	no	16.502	16.753	EPSD	COSMIC	8.808	Up-regulation
CMGC_CDK_CDK5_CDK5_ST	P49418	AMPH	Q00535	CDK5	T260	R256G	256	Missense	distal	-4	no	17.115	16.736	EPSD	COSMIC;GDSC;CCLE	8.808	Down-regulation
CMGC_CDK_CDK5_CDK5_ST	P49418	AMPH	Q00535	CDK5	T260	P261A	261	Missense	proximal	1	no	17.115	6.089	EPSD	COSMIC	8.808	Loss
CMGC_CDK_CDK5_CDK5_ST	P49418	AMPH	Q00535	CDK5	T260	L255F	255	Missense	distal	-5	no	17.115	17.006	EPSD	COSMIC	8.808	Down-regulation
CMGC_CDK_CDK5_CDK5_ST	P49418	AMPH	Q00535	CDK5	T260	P267H	267	Missense	distal	7	no	17.115	17.111	EPSD	COSMIC	8.808	Down-regulation
CMGC_CDK_CDK5_CDK5_ST	P49418	AMPH	Q00535	CDK5	T260	P261Q	261	Missense	proximal	1	no	17.115	8.140	EPSD	COSMIC	8.808	Loss
CMGC_CDK_CDK5_CDK5_ST	P49418	AMPH	Q00535	CDK5	S262	R256G	256	Missense	distal	-6	no	17.302	17.201	EPSD	COSMIC;GDSC;CCLE	8.808	Down-regulation
CMGC_CDK_CDK5_CDK5_ST	P49418	AMPH	Q00535	CDK5	S262	P261A	261	Missense	proximal	-1	no	17.302	17.298	EPSD	COSMIC	8.808	Down-regulation
CMGC_CDK_CDK5_CDK5_ST	P49418	AMPH	Q00535	CDK5	S262	L255F	255	Missense	distal	-7	no	17.302	17.274	EPSD	COSMIC	8.808	Down-regulation
CMGC_CDK_CDK5_CDK5_ST	P49418	AMPH	Q00535	CDK5	S262	P267H	267	Missense	distal	5	no	17.302	17.274	EPSD	COSMIC	8.808	Down-regulation
CMGC_CDK_CDK5_CDK5_ST	P49418	AMPH	Q00535	CDK5	S262	P261Q	261	Missense	proximal	-1	no	17.302	17.301	EPSD	COSMIC	8.808	Down-regulation
CMGC_CDK_CDK5_CDK5_ST	P49418	AMPH	Q00535	CDK5	S268	P261A	261	Missense	distal	-7	no	17.965	17.916	EPSD	COSMIC	8.808	Down-regulation
CMGC_CDK_CDK5_CDK5_ST	P49418	AMPH	Q00535	CDK5	S268	P273L	273	Missense	distal	5	no	17.965	17.793	EPSD	COSMIC	8.808	Down-regulation
CMGC_CDK_CDK5_CDK5_ST	P49418	AMPH	Q00535	CDK5	S268	P267H	267	Missense	proximal	-1	no	17.965	17.963	EPSD	COSMIC	8.808	Down-regulation
CMGC_CDK_CDK5_CDK5_ST	P49418	AMPH	Q00535	CDK5	S268	P261Q	261	Missense	distal	-7	no	17.965	17.949	EPSD	COSMIC	8.808	Down-regulation
CMGC_CDK_CDK5_CDK5_ST	P49418	AMPH	Q00535	CDK5	S272	H279R	279	Missense	distal	7	no	18.353	18.359	EPSD;PhosphoSitePlus	COSMIC	8.808	Up-regulation
CMGC_CDK_CDK5_CDK5_ST	P49418	AMPH	Q00535	CDK5	S272	P273L	273	Missense	proximal	1	no	18.353	6.403	EPSD;PhosphoSitePlus	COSMIC	8.808	Loss
CMGC_CDK_CDK5_CDK5_ST	P49418	AMPH	Q00535	CDK5	S272	P267H	267	Missense	distal	-5	no	18.353	18.283	EPSD;PhosphoSitePlus	COSMIC	8.808	Down-regulation
CMGC_CDK_CDK5_CDK5_ST	P49418	AMPH	Q00535	CDK5	S276	L281I	281	Missense	distal	5	no	18.246	18.341	EPSD;PhosphoSitePlus	COSMIC	8.808	Up-regulation
CMGC_CDK_CDK5_CDK5_ST	P49418	AMPH	Q00535	CDK5	S276	H279R	279	Missense	distal	3	no	18.246	19.265	EPSD;PhosphoSitePlus	COSMIC	8.808	Up-regulation
CMGC_CDK_CDK5_CDK5_ST	P49418	AMPH	Q00535	CDK5	S276	P273L	273	Missense	distal	-3	no	18.246	18.185	EPSD;PhosphoSitePlus	COSMIC	8.808	Down-regulation
CMGC_CDK_CDK5_CDK5_ST	P49418	AMPH	Q00535	CDK5	S285	P283S	283	Missense	proximal	-2	no	17.350	17.252	PhosphoSitePlus;EPSD	COSMIC	8.808	Down-regulation
CMGC_CDK_CDK5_CDK5_ST	P49418	AMPH	Q00535	CDK5	S285	P286L	286	Missense	proximal	1	no	17.350	5.401	PhosphoSitePlus;EPSD	COSMIC	8.808	Loss
CMGC_CDK_CDK5_CDK5_ST	P49418	AMPH	Q00535	CDK5	S285	L281I	281	Missense	distal	-4	no	17.350	17.554	PhosphoSitePlus;EPSD	COSMIC	8.808	Up-regulation
CMGC_CDK_CDK5_CDK5_ST	P49418	AMPH	Q00535	CDK5	S285	A284S	284	Missense	proximal	-1	no	17.350	17.356	PhosphoSitePlus;EPSD	COSMIC	8.808	Up-regulation
CMGC_CDK_CDK5_CDK5_ST	P49418	AMPH	Q00535	CDK5	S285	H279R	279	Missense	distal	-6	no	17.350	17.416	PhosphoSitePlus;EPSD	COSMIC	8.808	Up-regulation
CMGC_CDK_CDK5_CDK5_ST	P49418	AMPH	Q00535	CDK5	S293	P286L	286	Missense	distal	-7	no	16.929	16.877	EPSD	COSMIC	8.808	Down-regulation
CMGC_CDK_CDK5_CDK5_ST	P49418	AMPH	Q00535	CDK5	T310	T312K	312	Missense	proximal	2	no	18.925	19.049	EPSD	COSMIC	8.808	Up-regulation
CMGC_CDK_CDK5_CDK5_ST	P49418	AMPH	Q00535	CDK5	T310	T310A	310	Missense	central	0	yes	18.925	0.000	EPSD	COSMIC	8.808	Loss
CMGC_CDK_CDK5_CDK5_ST	P49418	AMPH	Q00535	CDK5	T336	S333R	333	Missense	distal	-3	no	15.867	15.881	EPSD	COSMIC	8.808	Up-regulation
CMGC_CDK_CDK5_CDK5_ST	P49418	AMPH	Q00535	CDK5	T336	S338F	338	Missense	proximal	2	no	15.867	15.657	EPSD	COSMIC	8.808	Down-regulation
CMGC_CDK_CDK5_CDK5_ST	P49418	AMPH	Q00535	CDK5	T445	L452H	452	Missense	distal	7	no	16.941	16.948	EPSD	COSMIC	8.808	Up-regulation
CMGC_CDK_CDK5_CDK5_ST	P49418	AMPH	Q00535	CDK5	T445	P446L	446	Missense	proximal	1	no	16.941	4.991	EPSD	COSMIC	8.808	Loss
CMGC_CDK_CDK5_CDK5_ST	P49418	AMPH	Q00535	CDK5	T456	E459K	459	Missense	distal	3	no	6.736	9.023	EPSD	COSMIC	8.808	Gain
CMGC_CDK_CDK5_CDK5_ST	Q15078	CDK5R1	Q00535	CDK5	S6	L7R	7	Missense	proximal	1	no	6.453	9.455	EPSD	COSMIC	8.808	Gain
CMGC_CDK_CDK5_CDK5_ST	Q15078	CDK5R1	Q00535	CDK5	S8	S6F	6	Missense	proximal	-2	no	18.241	17.681	PhosphoSitePlus;EPSD	COSMIC;GDSC;CCLE	8.808	Down-regulation
CMGC_CDK_CDK5_CDK5_ST	Q15078	CDK5R1	Q00535	CDK5	S8	L7R	7	Missense	proximal	-1	no	18.241	18.246	PhosphoSitePlus;EPSD	COSMIC	8.808	Up-regulation
CMGC_CDK_CDK5_CDK5_ST	Q15078	CDK5R1	Q00535	CDK5	S8	S10N	10	Missense	proximal	2	no	18.241	18.194	PhosphoSitePlus;EPSD	COSMIC	8.808	Down-regulation
CMGC_CDK_CDK5_CDK5_ST	Q15078	CDK5R1	Q00535	CDK5	T138	V133I	133	Missense	distal	-5	no	19.097	19.021	EPSD;PhosphoSitePlus	COSMIC	8.808	Down-regulation
CMGC_CDK_CDK5_CDK5_ST	Q15078	CDK5R1	Q00535	CDK5	T138	V144I	144	Missense	distal	6	no	19.097	19.093	EPSD;PhosphoSitePlus	COSMIC;GDSC;CCLE	8.808	Down-regulation
CMGC_CDK_CDK5_CDK5_ST	Q96QB1	DLC1	Q00535	CDK5	S306	N304K	304	Missense	proximal	-2	no	19.469	19.652	EPSD	COSMIC	8.808	Up-regulation
CMGC_CDK_CDK5_CDK5_ST	Q96QB1	DLC1	Q00535	CDK5	S306	K309M	309	Missense	distal	3	no	19.469	16.789	EPSD	COSMIC	8.808	Down-regulation
CMGC_CDK_CDK5_CDK5_ST	Q96QB1	DLC1	Q00535	CDK5	S306	P307S	307	Missense	proximal	1	no	19.469	7.567	EPSD	COSMIC	8.808	Loss
CMGC_CDK_CDK5_CDK5_ST	Q96QB1	DLC1	Q00535	CDK5	S306	P307L	307	Missense	proximal	1	no	19.469	7.519	EPSD	COSMIC	8.808	Loss
CMGC_CDK_CDK5_CDK5_ST	Q96QB1	DLC1	Q00535	CDK5	S378	N385D	385	Missense	distal	7	no	18.836	18.832	EPSD	COSMIC	8.808	Down-regulation
CMGC_CDK_CDK5_CDK5_ST	Q96QB1	DLC1	Q00535	CDK5	S378	G381R	381	Missense	distal	3	no	18.836	20.218	EPSD	COSMIC	8.808	Up-regulation
CMGC_CDK_CDK5_CDK5_ST	Q96QB1	DLC1	Q00535	CDK5	S380	G381R	381	Missense	proximal	1	no	-2.225	10.244	EPSD	COSMIC	8.808	Gain
CMGC_CDK_CDK5_CDK5_ST	Q96QB1	DLC1	Q00535	CDK5	T382	R388W	388	Missense	distal	6	no	18.246	18.229	EPSD	COSMIC	8.808	Down-regulation
CMGC_CDK_CDK5_CDK5_ST	Q96QB1	DLC1	Q00535	CDK5	T382	N385D	385	Missense	distal	3	no	18.246	17.827	EPSD	COSMIC	8.808	Down-regulation
CMGC_CDK_CDK5_CDK5_ST	Q96QB1	DLC1	Q00535	CDK5	T382	G381R	381	Missense	proximal	-1	no	18.246	18.250	EPSD	COSMIC	8.808	Up-regulation
CMGC_CDK_CDK5_CDK5_ST	Q96QB1	DLC1	Q00535	CDK5	T384	R388W	388	Missense	distal	4	no	10.132	10.060	EPSD	COSMIC	8.808	Down-regulation
CMGC_CDK_CDK5_CDK5_ST	Q96QB1	DLC1	Q00535	CDK5	T384	N385D	385	Missense	proximal	1	no	10.132	8.665	EPSD	COSMIC	8.808	Loss
CMGC_CDK_CDK5_CDK5_ST	Q96QB1	DLC1	Q00535	CDK5	T384	G381R	381	Missense	distal	-3	no	10.132	10.187	EPSD	COSMIC	8.808	Up-regulation
CMGC_CDK_CDK5_CDK5_ST	Q96QB1	DLC1	Q00535	CDK5	S517	V511L	511	Missense	distal	-6	no	19.931	19.853	EPSD	COSMIC	8.808	Down-regulation
CMGC_CDK_CDK5_CDK5_ST	Q96QB1	DLC1	Q00535	CDK5	S517	R522Q	522	Missense	distal	5	no	19.931	19.806	EPSD	COSMIC	8.808	Down-regulation
CMGC_CDK_CDK5_CDK5_ST	Q96QB1	DLC1	Q00535	CDK5	S517	K513E	513	Missense	distal	-4	no	19.931	19.428	EPSD	COSMIC	8.808	Down-regulation
CMGC_CDK_CDK5_CDK5_ST	Q96QB1	DLC1	Q00535	CDK5	S557	D561E	561	Missense	distal	4	no	17.606	17.613	PhosphoSitePlus;EPSD	COSMIC	8.808	Up-regulation
CMGC_CDK_CDK5_CDK5_ST	Q96QB1	DLC1	Q00535	CDK5	S557	E552D	552	Missense	distal	-5	no	17.606	17.615	PhosphoSitePlus;EPSD	COSMIC	8.808	Up-regulation
CMGC_CDK_CDK5_CDK5_ST	Q96QB1	DLC1	Q00535	CDK5	S557	F553I	553	Missense	distal	-4	no	17.606	18.151	PhosphoSitePlus;EPSD	COSMIC	8.808	Up-regulation
CMGC_CDK_CDK5_CDK5_ST	Q96QB1	DLC1	Q00535	CDK5	S557	E552K	552	Missense	distal	-5	no	17.606	17.895	PhosphoSitePlus;EPSD	COSMIC	8.808	Up-regulation
CMGC_CDK_CDK5_CDK5_ST	Q96QB1	DLC1	Q00535	CDK5	S557	P558H	558	Missense	proximal	1	no	17.606	-0.907	PhosphoSitePlus;EPSD	COSMIC	8.808	Loss
CMGC_CDK_CDK5_CDK5_ST	Q96QB1	DLC1	Q00535	CDK5	S557	D554N	554	Missense	distal	-3	no	17.606	17.628	PhosphoSitePlus;EPSD	COSMIC	8.808	Up-regulation
CMGC_CDK_CDK5_CDK5_ST	Q96QB1	DLC1	Q00535	CDK5	S566	D561E	561	Missense	distal	-5	no	16.698	16.688	EPSD	COSMIC	8.808	Down-regulation
CMGC_CDK_CDK5_CDK5_ST	Q96QB1	DLC1	Q00535	CDK5	S566	P567L	567	Missense	proximal	1	no	16.698	4.748	EPSD	COSMIC;GDSC	8.808	Loss
CMGC_CDK_CDK5_CDK5_ST	Q96QB1	DLC1	Q00535	CDK5	S566	P572Q	572	Missense	distal	6	no	16.698	16.695	EPSD	COSMIC	8.808	Down-regulation
CMGC_CDK_CDK5_CDK5_ST	Q96QB1	DLC1	Q00535	CDK5	S577	P578L	578	Missense	proximal	1	no	18.155	6.205	EPSD	COSMIC	8.808	Loss
CMGC_CDK_CDK5_CDK5_ST	Q96QB1	DLC1	Q00535	CDK5	S577	G579R	579	Missense	proximal	2	no	18.155	18.327	EPSD	COSMIC	8.808	Up-regulation
CMGC_CDK_CDK5_CDK5_ST	Q96QB1	DLC1	Q00535	CDK5	S577	G580V	580	Missense	distal	3	no	18.155	18.145	EPSD	COSMIC	8.808	Down-regulation
CMGC_CDK_CDK5_CDK5_ST	Q96QB1	DLC1	Q00535	CDK5	S577	G575D	575	Missense	proximal	-2	no	18.155	18.285	EPSD	COSMIC	8.808	Up-regulation
CMGC_CDK_CDK5_CDK5_ST	Q96QB1	DLC1	Q00535	CDK5	S577	P572Q	572	Missense	distal	-5	no	18.155	18.096	EPSD	COSMIC	8.808	Down-regulation
CMGC_CDK_CDK5_CDK5_ST	Q96QB1	DLC1	Q00535	CDK5	S577	T581M	581	Missense	distal	4	no	18.155	18.062	EPSD	COSMIC	8.808	Down-regulation
CMGC_CDK_CDK5_CDK5_ST	Q96QB1	DLC1	Q00535	CDK5	T615	R617W	617	Missense	proximal	2	no	17.849	17.657	EPSD	COSMIC	8.808	Down-regulation
CMGC_CDK_CDK5_CDK5_ST	Q96QB1	DLC1	Q00535	CDK5	T615	V621I	621	Missense	distal	6	no	17.849	17.845	EPSD	COSMIC;GDSC;CCLE	8.808	Down-regulation
CMGC_CDK_CDK5_CDK5_ST	Q96QB1	DLC1	Q00535	CDK5	T615	P609H	609	Missense	distal	-6	no	17.849	17.829	EPSD	COSMIC	8.808	Down-regulation
CMGC_CDK_CDK5_CDK5_ST	Q96QB1	DLC1	Q00535	CDK5	S628	A631V	631	Missense	distal	3	no	8.637	8.889	EPSD	COSMIC	8.808	Gain
CMGC_CDK_CDK5_CDK5_ST	Q96QB1	DLC1	Q00535	CDK5	S642	S647C	647	Missense	distal	5	no	16.005	15.811	EPSD;PhosphoSitePlus	COSMIC	8.808	Down-regulation
CMGC_CDK_CDK5_CDK5_ST	Q96QB1	DLC1	Q00535	CDK5	S642	G638V	638	Missense	distal	-4	no	16.005	16.363	EPSD;PhosphoSitePlus	COSMIC	8.808	Up-regulation
CMGC_CDK_CDK5_CDK5_ST	Q96QB1	DLC1	Q00535	CDK5	S735	S741T	741	Missense	distal	6	no	9.687	9.688	EPSD	COSMIC	8.808	Up-regulation
CMGC_CDK_CDK5_CDK5_ST	Q96QB1	DLC1	Q00535	CDK5	S735	M728V	728	Missense	distal	-7	no	9.687	9.741	EPSD	COSMIC	8.808	Up-regulation
CMGC_CDK_CDK5_CDK5_ST	Q96QB1	DLC1	Q00535	CDK5	S735	T738M	738	Missense	distal	3	no	9.687	8.190	EPSD	COSMIC	8.808	Loss
CMGC_CDK_CDK5_CDK5_ST	Q96QB1	DLC1	Q00535	CDK5	S735	R730Q	730	Missense	distal	-5	no	9.687	9.526	EPSD	COSMIC;GDSC	8.808	Down-regulation
CMGC_CDK_CDK5_CDK5_ST	Q96QB1	DLC1	Q00535	CDK5	S735	R732T	732	Missense	distal	-3	no	9.687	9.671	EPSD	COSMIC	8.808	Down-regulation
CMGC_CDK_CDK5_CDK5_ST	Q96QB1	DLC1	Q00535	CDK5	S735	S733F	733	Missense	proximal	-2	no	9.687	9.128	EPSD	COSMIC	8.808	Down-regulation
CMGC_CDK_CDK5_CDK5_ST	Q96QB1	DLC1	Q00535	CDK5	T738	S741T	741	Missense	distal	3	no	8.609	9.165	EPSD	COSMIC	8.808	Gain
CMGC_CDK_CDK5_CDK5_ST	Q96QB1	DLC1	Q00535	CDK5	S745	A752V	752	Missense	distal	7	no	9.599	9.606	EPSD	COSMIC	8.808	Up-regulation
CMGC_CDK_CDK5_CDK5_ST	Q96QB1	DLC1	Q00535	CDK5	S745	S744T	744	Missense	proximal	-1	no	9.599	9.598	EPSD	COSMIC	8.808	Down-regulation
CMGC_CDK_CDK5_CDK5_ST	Q96QB1	DLC1	Q00535	CDK5	S745	S741T	741	Missense	distal	-4	no	9.599	9.097	EPSD	COSMIC	8.808	Down-regulation
CMGC_CDK_CDK5_CDK5_ST	Q96QB1	DLC1	Q00535	CDK5	S745	T738M	738	Missense	distal	-7	no	9.599	9.541	EPSD	COSMIC	8.808	Down-regulation
CMGC_CDK_CDK5_CDK5_ST	Q96QB1	DLC1	Q00535	CDK5	S745	A752G	752	Missense	distal	7	no	9.599	9.600	EPSD	COSMIC	8.808	Up-regulation
CMGC_CDK_CDK5_CDK5_ST	Q96QB1	DLC1	Q00535	CDK5	T755	A752V	752	Missense	distal	-3	no	17.881	17.919	EPSD	COSMIC	8.808	Up-regulation
CMGC_CDK_CDK5_CDK5_ST	Q96QB1	DLC1	Q00535	CDK5	T755	S757N	757	Missense	proximal	2	no	17.881	17.835	EPSD	COSMIC	8.808	Down-regulation
CMGC_CDK_CDK5_CDK5_ST	Q96QB1	DLC1	Q00535	CDK5	T755	T762S	762	Missense	distal	7	no	17.881	17.883	EPSD	COSMIC	8.808	Up-regulation
CMGC_CDK_CDK5_CDK5_ST	Q96QB1	DLC1	Q00535	CDK5	T755	A752G	752	Missense	distal	-3	no	17.881	17.887	EPSD	COSMIC	8.808	Up-regulation
CMGC_CDK_CDK5_CDK5_ST	Q96QB1	DLC1	Q00535	CDK5	S757	A752V	752	Missense	distal	-5	no	18.767	18.892	EPSD	COSMIC	8.808	Up-regulation
CMGC_CDK_CDK5_CDK5_ST	Q96QB1	DLC1	Q00535	CDK5	S757	S757N	757	Missense	central	0	yes	18.767	0.000	EPSD	COSMIC	8.808	Loss
CMGC_CDK_CDK5_CDK5_ST	Q96QB1	DLC1	Q00535	CDK5	S757	R763Q	763	Missense	distal	6	no	18.767	18.756	EPSD	COSMIC	8.808	Down-regulation
CMGC_CDK_CDK5_CDK5_ST	Q96QB1	DLC1	Q00535	CDK5	S757	T762S	762	Missense	distal	5	no	18.767	18.768	EPSD	COSMIC	8.808	Up-regulation
CMGC_CDK_CDK5_CDK5_ST	Q96QB1	DLC1	Q00535	CDK5	S757	R763W	763	Missense	distal	6	no	18.767	18.750	EPSD	COSMIC	8.808	Down-regulation
CMGC_CDK_CDK5_CDK5_ST	Q96QB1	DLC1	Q00535	CDK5	S757	A752G	752	Missense	distal	-5	no	18.767	18.777	EPSD	COSMIC	8.808	Up-regulation
CMGC_CDK_CDK5_CDK5_ST	Q96QB1	DLC1	Q00535	CDK5	S828	N833D	833	Missense	distal	5	no	17.712	17.643	EPSD	COSMIC	8.808	Down-regulation
CMGC_CDK_CDK5_CDK5_ST	Q96QB1	DLC1	Q00535	CDK5	S828	S828F	828	Missense	central	0	yes	17.712	0.000	EPSD	COSMIC	8.808	Loss
CMGC_CDK_CDK5_CDK5_ST	Q96QB1	DLC1	Q00535	CDK5	S828	T823I	823	Missense	distal	-5	no	17.712	17.605	EPSD	COSMIC	8.808	Down-regulation
CMGC_CDK_CDK5_CDK5_ST	Q96QB1	DLC1	Q00535	CDK5	S828	P829L	829	Missense	proximal	1	no	17.712	5.762	EPSD	COSMIC	8.808	Loss
CMGC_CDK_CDK5_CDK5_ST	Q96QB1	DLC1	Q00535	CDK5	S859	R853M	853	Missense	distal	-6	no	17.929	17.773	EPSD;PhosphoSitePlus	COSMIC	8.808	Down-regulation
CMGC_CDK_CDK5_CDK5_ST	Q96QB1	DLC1	Q00535	CDK5	S859	N855D	855	Missense	distal	-4	no	17.929	17.765	EPSD;PhosphoSitePlus	COSMIC	8.808	Down-regulation
CMGC_CDK_CDK5_CDK5_ST	Q96QB1	DLC1	Q00535	CDK5	S859	S859G	859	Missense	central	0	yes	17.929	0.000	EPSD;PhosphoSitePlus	COSMIC	8.808	Loss
CMGC_CDK_CDK5_CDK5_ST	Q96QB1	DLC1	Q00535	CDK5	S859	E862K	862	Missense	distal	3	no	17.929	20.215	EPSD;PhosphoSitePlus	COSMIC	8.808	Up-regulation
CMGC_CDK_CDK5_CDK5_ST	Q96QB1	DLC1	Q00535	CDK5	S874	R875H	875	Missense	proximal	1	no	9.351	-0.214	EPSD	COSMIC	8.808	Loss
CMGC_CDK_CDK5_CDK5_ST	Q96QB1	DLC1	Q00535	CDK5	S874	D880N	880	Missense	distal	6	no	9.351	9.357	EPSD	COSMIC	8.808	Up-regulation
CMGC_CDK_CDK5_CDK5_ST	Q96QB1	DLC1	Q00535	CDK5	S928	D929N	929	Missense	proximal	1	no	7.871	9.338	EPSD	COSMIC	8.808	Gain
CMGC_CDK_CDK5_CDK5_ST	Q96QB1	DLC1	Q00535	CDK5	S941	S939L	939	Missense	proximal	-2	no	17.171	16.855	EPSD	COSMIC	8.808	Down-regulation
CMGC_CDK_CDK5_CDK5_ST	Q96QB1	DLC1	Q00535	CDK5	S941	P944S	944	Missense	distal	3	no	17.171	17.151	EPSD	COSMIC	8.808	Down-regulation
CMGC_CDK_CDK5_CDK5_ST	Q96QB1	DLC1	Q00535	CDK5	S941	P944T	944	Missense	distal	3	no	17.171	17.707	EPSD	COSMIC;GDSC;CCLE	8.808	Up-regulation
CMGC_CDK_CDK5_CDK5_ST	Q96QB1	DLC1	Q00535	CDK5	S941	A936T	936	Missense	distal	-5	no	17.171	17.327	EPSD	COSMIC	8.808	Up-regulation
CMGC_CDK_CDK5_CDK5_ST	Q96QB1	DLC1	Q00535	CDK5	S941	P942R	942	Missense	proximal	1	no	17.171	8.224	EPSD	COSMIC	8.808	Loss
CMGC_CDK_CDK5_CDK5_ST	Q96QB1	DLC1	Q00535	CDK5	S941	S946L	946	Missense	distal	5	no	17.171	16.986	EPSD	COSMIC	8.808	Down-regulation
CMGC_CDK_CDK5_CDK5_ST	Q96QB1	DLC1	Q00535	CDK5	S946	S939L	939	Missense	distal	-7	no	18.082	18.025	EPSD;PhosphoSitePlus	COSMIC	8.808	Down-regulation
CMGC_CDK_CDK5_CDK5_ST	Q96QB1	DLC1	Q00535	CDK5	S946	P944S	944	Missense	proximal	-2	no	18.082	17.983	EPSD;PhosphoSitePlus	COSMIC	8.808	Down-regulation
CMGC_CDK_CDK5_CDK5_ST	Q96QB1	DLC1	Q00535	CDK5	S946	P944T	944	Missense	proximal	-2	no	18.082	17.942	EPSD;PhosphoSitePlus	COSMIC;GDSC;CCLE	8.808	Down-regulation
CMGC_CDK_CDK5_CDK5_ST	Q96QB1	DLC1	Q00535	CDK5	S946	D953N	953	Missense	distal	7	no	18.082	18.086	EPSD;PhosphoSitePlus	COSMIC	8.808	Up-regulation
CMGC_CDK_CDK5_CDK5_ST	Q96QB1	DLC1	Q00535	CDK5	S946	P942R	942	Missense	distal	-4	no	18.082	17.966	EPSD;PhosphoSitePlus	COSMIC	8.808	Down-regulation
CMGC_CDK_CDK5_CDK5_ST	Q96QB1	DLC1	Q00535	CDK5	S946	S946L	946	Missense	central	0	yes	18.082	0.000	EPSD;PhosphoSitePlus	COSMIC	8.808	Loss
CMGC_CDK_CDK5_CDK5_ST	Q96QB1	DLC1	Q00535	CDK5	S995	G989V	989	Missense	distal	-6	no	9.504	9.554	EPSD	COSMIC	8.808	Up-regulation
CMGC_CDK_CDK5_CDK5_ST	Q96QB1	DLC1	Q00535	CDK5	S995	R1001Q	1001	Missense	distal	6	no	9.504	9.493	EPSD	COSMIC	8.808	Down-regulation
CMGC_CDK_CDK5_CDK5_ST	Q96QB1	DLC1	Q00535	CDK5	S1291	T1298S	1298	Missense	distal	7	no	10.935	10.937	EPSD	COSMIC	8.808	Up-regulation
CMGC_CDK_CDK5_CDK5_ST	Q96QB1	DLC1	Q00535	CDK5	S1291	E1289K	1289	Missense	proximal	-2	no	10.935	11.348	EPSD	COSMIC	8.808	Up-regulation
CMGC_CDK_CDK5_CDK5_ST	Q96QB1	DLC1	Q00535	CDK5	S1291	T1298A	1298	Missense	distal	7	no	10.935	10.927	EPSD	COSMIC	8.808	Down-regulation
CMGC_CDK_CDK5_CDK5_ST	Q96QB1	DLC1	Q00535	CDK5	S1291	N1295D	1295	Missense	distal	4	no	10.935	10.905	EPSD	COSMIC	8.808	Down-regulation
CMGC_CDK_CDK5_CDK5_ST	Q96QB1	DLC1	Q00535	CDK5	S1291	T1298I	1298	Missense	distal	7	no	10.935	10.930	EPSD	COSMIC	8.808	Down-regulation
CMGC_CDK_CDK5_CDK5_ST	Q96QB1	DLC1	Q00535	CDK5	S1291	M1290I	1290	Missense	proximal	-1	no	10.935	10.939	EPSD	COSMIC	8.808	Up-regulation
CMGC_CDK_CDK5_CDK5_ST	Q96QB1	DLC1	Q00535	CDK5	S1291	E1289G	1289	Missense	proximal	-2	no	10.935	10.912	EPSD	COSMIC	8.808	Down-regulation
CMGC_CDK_CDK5_CDK5_ST	Q96QB1	DLC1	Q00535	CDK5	S1291	P1287A	1287	Missense	distal	-4	no	10.935	10.380	EPSD	COSMIC	8.808	Down-regulation
CMGC_CDK_CDK5_CDK5_ST	Q96QB1	DLC1	Q00535	CDK5	S1291	R1294S	1294	Missense	distal	3	no	10.935	9.517	EPSD	COSMIC	8.808	Down-regulation
CMGC_CDK_CDK5_CDK5_ST	Q96QB1	DLC1	Q00535	CDK5	S1291	R1292Q	1292	Missense	proximal	1	no	10.935	10.906	EPSD	COSMIC	8.808	Down-regulation
CMGC_CDK_CDK5_CDK5_ST	Q96QB1	DLC1	Q00535	CDK5	S1516	F1515L	1515	Missense	proximal	-1	no	9.023	9.025	EPSD	COSMIC	8.808	Up-regulation
CMGC_CDK_CDK5_CDK5_ST	P30086	PEBP1	Q00535	CDK5	T42	R49T	49	Missense	distal	7	no	16.427	16.424	PhosphoSitePlus	COSMIC;GDSC;CCLE	8.808	Down-regulation
CMGC_CDK_CDK5_CDK5_ST	P30086	PEBP1	Q00535	CDK5	T44	R49T	49	Missense	distal	5	no	10.246	10.182	EPSD	COSMIC;GDSC;CCLE	8.808	Down-regulation
CMGC_CDK_CDK5_CDK5_ST	P30086	PEBP1	Q00535	CDK5	S109	G110R	110	Missense	proximal	1	no	-3.222	9.247	EPSD	COSMIC	8.808	Gain
CMGC_CDK_CDK5_CDK5_ST	P30086	PEBP1	Q00535	CDK5	S139	E135K	135	Missense	distal	-4	no	8.319	8.822	EPSD	COSMIC	8.808	Gain
CMGC_CDK_CDK5_CDK5_ST	Q3V6T2	CCDC88A	Q00535	CDK5	S16	T15A	15	Missense	proximal	-1	no	18.744	18.740	EPSD	COSMIC	8.808	Down-regulation
CMGC_CDK_CDK5_CDK5_ST	Q3V6T2	CCDC88A	Q00535	CDK5	S233	S229C	229	Missense	distal	-4	no	17.964	16.940	EPSD	COSMIC	8.808	Down-regulation
CMGC_CDK_CDK5_CDK5_ST	Q3V6T2	CCDC88A	Q00535	CDK5	S233	S228T	228	Missense	distal	-5	no	17.964	17.938	EPSD	COSMIC	8.808	Down-regulation
CMGC_CDK_CDK5_CDK5_ST	Q3V6T2	CCDC88A	Q00535	CDK5	S237	R242Q	242	Missense	distal	5	no	17.274	17.149	EPSD	COSMIC	8.808	Down-regulation
CMGC_CDK_CDK5_CDK5_ST	Q3V6T2	CCDC88A	Q00535	CDK5	S245	H248Y	248	Missense	distal	3	no	9.460	8.293	EPSD	COSMIC	8.808	Loss
CMGC_CDK_CDK5_CDK5_ST	Q3V6T2	CCDC88A	Q00535	CDK5	S245	S250L	250	Missense	distal	5	no	9.460	9.275	EPSD	COSMIC;GDSC;CCLE	8.808	Down-regulation
CMGC_CDK_CDK5_CDK5_ST	Q3V6T2	CCDC88A	Q00535	CDK5	S245	R242Q	242	Missense	distal	-3	no	9.460	9.434	EPSD	COSMIC	8.808	Down-regulation
CMGC_CDK_CDK5_CDK5_ST	Q3V6T2	CCDC88A	Q00535	CDK5	S245	R246T	246	Missense	proximal	1	no	9.460	7.920	EPSD	COSMIC	8.808	Loss
CMGC_CDK_CDK5_CDK5_ST	Q3V6T2	CCDC88A	Q00535	CDK5	S775	N774K	774	Missense	proximal	-1	no	10.461	10.465	EPSD	COSMIC	8.808	Up-regulation
CMGC_CDK_CDK5_CDK5_ST	Q3V6T2	CCDC88A	Q00535	CDK5	S775	I779V	779	Missense	distal	4	no	10.461	10.485	EPSD	COSMIC;GDSC;CCLE	8.808	Up-regulation
CMGC_CDK_CDK5_CDK5_ST	Q3V6T2	CCDC88A	Q00535	CDK5	S1020	Q1018H	1018	Missense	proximal	-2	no	17.256	17.131	EPSD	COSMIC	8.808	Down-regulation
CMGC_CDK_CDK5_CDK5_ST	Q3V6T2	CCDC88A	Q00535	CDK5	S1020	R1015M	1015	Missense	distal	-5	no	17.256	16.892	EPSD	COSMIC;CCLE	8.808	Down-regulation
CMGC_CDK_CDK5_CDK5_ST	Q3V6T2	CCDC88A	Q00535	CDK5	S1020	R1015K	1015	Missense	distal	-5	no	17.256	17.290	EPSD	COSMIC	8.808	Up-regulation
CMGC_CDK_CDK5_CDK5_ST	Q3V6T2	CCDC88A	Q00535	CDK5	S1020	Q1018K	1018	Missense	proximal	-2	no	17.256	17.419	EPSD	COSMIC	8.808	Up-regulation
CMGC_CDK_CDK5_CDK5_ST	Q3V6T2	CCDC88A	Q00535	CDK5	S1034	N1028D	1028	Missense	distal	-6	no	9.591	9.552	EPSD	COSMIC	8.808	Down-regulation
CMGC_CDK_CDK5_CDK5_ST	Q3V6T2	CCDC88A	Q00535	CDK5	S1034	R1032Q	1032	Missense	proximal	-2	no	9.591	9.454	EPSD	COSMIC	8.808	Down-regulation
CMGC_CDK_CDK5_CDK5_ST	Q3V6T2	CCDC88A	Q00535	CDK5	S1034	T1037M	1037	Missense	distal	3	no	9.591	8.094	EPSD	COSMIC;CCLE	8.808	Loss
CMGC_CDK_CDK5_CDK5_ST	Q3V6T2	CCDC88A	Q00535	CDK5	S1034	W1030C	1030	Missense	distal	-4	no	9.591	9.377	EPSD	COSMIC	8.808	Down-regulation
CMGC_CDK_CDK5_CDK5_ST	Q3V6T2	CCDC88A	Q00535	CDK5	S1176	L1177R	1177	Missense	proximal	1	no	6.215	9.217	EPSD	COSMIC	8.808	Gain
CMGC_CDK_CDK5_CDK5_ST	Q3V6T2	CCDC88A	Q00535	CDK5	S1314	G1318E	1318	Missense	distal	4	no	10.128	10.126	EPSD	COSMIC	8.808	Down-regulation
CMGC_CDK_CDK5_CDK5_ST	Q3V6T2	CCDC88A	Q00535	CDK5	S1314	S1314C	1314	Missense	central	0	yes	10.128	0.000	EPSD	COSMIC;CCLE	8.808	Loss
CMGC_CDK_CDK5_CDK5_ST	Q3V6T2	CCDC88A	Q00535	CDK5	S1314	K1317I	1317	Missense	distal	3	no	10.128	7.969	EPSD	COSMIC	8.808	Loss
CMGC_CDK_CDK5_CDK5_ST	Q3V6T2	CCDC88A	Q00535	CDK5	S1387	K1382T	1382	Missense	distal	-5	no	17.968	17.828	EPSD	COSMIC	8.808	Down-regulation
CMGC_CDK_CDK5_CDK5_ST	Q3V6T2	CCDC88A	Q00535	CDK5	S1387	S1387C	1387	Missense	central	0	yes	17.968	0.000	EPSD	COSMIC	8.808	Loss
CMGC_CDK_CDK5_CDK5_ST	Q3V6T2	CCDC88A	Q00535	CDK5	S1387	F1383C	1383	Missense	distal	-4	no	17.968	18.105	EPSD	COSMIC	8.808	Up-regulation
CMGC_CDK_CDK5_CDK5_ST	Q3V6T2	CCDC88A	Q00535	CDK5	S1387	F1383V	1383	Missense	distal	-4	no	17.968	18.647	EPSD	COSMIC	8.808	Up-regulation
CMGC_CDK_CDK5_CDK5_ST	Q3V6T2	CCDC88A	Q00535	CDK5	S1387	P1388L	1388	Missense	proximal	1	no	17.968	6.019	EPSD	COSMIC	8.808	Loss
CMGC_CDK_CDK5_CDK5_ST	Q3V6T2	CCDC88A	Q00535	CDK5	T1421	R1414H	1414	Missense	distal	-7	no	19.246	19.215	EPSD	COSMIC	8.808	Down-regulation
CMGC_CDK_CDK5_CDK5_ST	Q3V6T2	CCDC88A	Q00535	CDK5	T1421	R1414C	1414	Missense	distal	-7	no	19.246	19.174	EPSD	COSMIC	8.808	Down-regulation
CMGC_CDK_CDK5_CDK5_ST	Q3V6T2	CCDC88A	Q00535	CDK5	S1439	Q1440P	1440	Missense	proximal	1	no	7.775	16.751	EPSD	COSMIC	8.808	Gain
CMGC_CDK_CDK5_CDK5_ST	Q3V6T2	CCDC88A	Q00535	CDK5	S1566	D1572E	1572	Missense	distal	6	no	17.335	17.336	EPSD	COSMIC	8.808	Up-regulation
CMGC_CDK_CDK5_CDK5_ST	Q3V6T2	CCDC88A	Q00535	CDK5	S1566	D1572N	1572	Missense	distal	6	no	17.335	17.341	EPSD	COSMIC	8.808	Up-regulation
CMGC_CDK_CDK5_CDK5_ST	Q3V6T2	CCDC88A	Q00535	CDK5	S1578	D1572E	1572	Missense	distal	-6	no	9.789	9.799	EPSD	COSMIC	8.808	Up-regulation
CMGC_CDK_CDK5_CDK5_ST	Q3V6T2	CCDC88A	Q00535	CDK5	S1578	V1580A	1580	Missense	proximal	2	no	9.789	9.708	EPSD	COSMIC	8.808	Down-regulation
CMGC_CDK_CDK5_CDK5_ST	Q3V6T2	CCDC88A	Q00535	CDK5	S1578	S1574Y	1574	Missense	distal	-4	no	9.789	8.808	EPSD	COSMIC	8.808	Down-regulation
CMGC_CDK_CDK5_CDK5_ST	Q3V6T2	CCDC88A	Q00535	CDK5	S1578	T1576M	1576	Missense	proximal	-2	no	9.789	9.356	EPSD	COSMIC	8.808	Down-regulation
CMGC_CDK_CDK5_CDK5_ST	Q3V6T2	CCDC88A	Q00535	CDK5	S1578	D1572N	1572	Missense	distal	-6	no	9.789	9.828	EPSD	COSMIC	8.808	Up-regulation
CMGC_CDK_CDK5_CDK5_ST	Q3V6T2	CCDC88A	Q00535	CDK5	S1583	A1586T	1586	Missense	distal	3	no	8.638	9.419	EPSD	COSMIC	8.808	Gain
CMGC_CDK_CDK5_CDK5_ST	Q3V6T2	CCDC88A	Q00535	CDK5	S1653	I1660M	1660	Missense	distal	7	no	17.355	17.346	EPSD	COSMIC	8.808	Down-regulation
CMGC_CDK_CDK5_CDK5_ST	Q3V6T2	CCDC88A	Q00535	CDK5	S1653	R1651T	1651	Missense	proximal	-2	no	17.355	17.270	EPSD	COSMIC	8.808	Down-regulation
CMGC_CDK_CDK5_CDK5_ST	Q3V6T2	CCDC88A	Q00535	CDK5	S1653	L1656F	1656	Missense	distal	3	no	17.355	17.229	EPSD	COSMIC	8.808	Down-regulation
CMGC_CDK_CDK5_CDK5_ST	Q3V6T2	CCDC88A	Q00535	CDK5	S1666	H1669Y	1669	Missense	distal	3	no	9.088	7.921	EPSD	COSMIC	8.808	Loss
CMGC_CDK_CDK5_CDK5_ST	Q3V6T2	CCDC88A	Q00535	CDK5	S1666	I1660M	1660	Missense	distal	-6	no	9.088	9.012	EPSD	COSMIC	8.808	Down-regulation
CMGC_CDK_CDK5_CDK5_ST	Q3V6T2	CCDC88A	Q00535	CDK5	S1666	R1667L	1667	Missense	proximal	1	no	9.088	6.086	EPSD	COSMIC	8.808	Loss
CMGC_CDK_CDK5_CDK5_ST	Q3V6T2	CCDC88A	Q00535	CDK5	S1666	H1669R	1669	Missense	distal	3	no	9.088	10.107	EPSD	COSMIC	8.808	Up-regulation
CMGC_CDK_CDK5_CDK5_ST	Q3V6T2	CCDC88A	Q00535	CDK5	S1666	L1664F	1664	Missense	proximal	-2	no	9.088	8.845	EPSD	COSMIC	8.808	Down-regulation
CMGC_CDK_CDK5_CDK5_ST	Q3V6T2	CCDC88A	Q00535	CDK5	S1675	G1677E	1677	Missense	proximal	2	no	17.543	17.514	PhosphoSitePlus	COSMIC	8.808	Down-regulation
CMGC_CDK_CDK5_CDK5_ST	Q3V6T2	CCDC88A	Q00535	CDK5	S1675	H1669Y	1669	Missense	distal	-6	no	17.543	17.468	PhosphoSitePlus	COSMIC	8.808	Down-regulation
CMGC_CDK_CDK5_CDK5_ST	Q3V6T2	CCDC88A	Q00535	CDK5	S1675	H1669R	1669	Missense	distal	-6	no	17.543	17.608	PhosphoSitePlus	COSMIC	8.808	Up-regulation
CMGC_CDK_CDK5_CDK5_ST	Q3V6T2	CCDC88A	Q00535	CDK5	T1739	R1746Q	1746	Missense	distal	7	no	15.543	15.537	EPSD	COSMIC	8.808	Down-regulation
CMGC_CDK_CDK5_CDK5_ST	Q3V6T2	CCDC88A	Q00535	CDK5	T1739	R1746W	1746	Missense	distal	7	no	15.543	15.532	EPSD	COSMIC;GDSC	8.808	Down-regulation
CMGC_CDK_CDK5_CDK5_ST	Q3V6T2	CCDC88A	Q00535	CDK5	T1739	P1740S	1740	Missense	proximal	1	no	15.543	3.642	EPSD	COSMIC	8.808	Loss
CMGC_CDK_CDK5_CDK5_ST	Q3V6T2	CCDC88A	Q00535	CDK5	T1739	V1735L	1735	Missense	distal	-4	no	15.543	15.206	EPSD	COSMIC	8.808	Down-regulation
CMGC_CDK_CDK5_CDK5_ST	Q3V6T2	CCDC88A	Q00535	CDK5	T1774	S1768C	1768	Missense	distal	-6	no	16.890	16.744	EPSD	COSMIC	8.808	Down-regulation
CMGC_CDK_CDK5_CDK5_ST	Q3V6T2	CCDC88A	Q00535	CDK5	T1774	P1775S	1775	Missense	proximal	1	no	16.890	4.989	EPSD	COSMIC	8.808	Loss
CMGC_CDK_CDK5_CDK5_ST	Q3V6T2	CCDC88A	Q00535	CDK5	T1774	I1781M	1781	Missense	distal	7	no	16.890	16.882	EPSD	COSMIC	8.808	Down-regulation
CMGC_CDK_CDK5_CDK5_ST	Q3V6T2	CCDC88A	Q00535	CDK5	T1774	S1769Y	1769	Missense	distal	-5	no	16.890	16.641	EPSD	COSMIC	8.808	Down-regulation
CMGC_CDK_CDK5_CDK5_ST	Q3V6T2	CCDC88A	Q00535	CDK5	T1774	G1776S	1776	Missense	proximal	2	no	16.890	16.963	EPSD	COSMIC	8.808	Up-regulation
CMGC_CDK_CDK5_CDK5_ST	Q3V6T2	CCDC88A	Q00535	CDK5	T1774	A1770T	1770	Missense	distal	-4	no	16.890	17.290	EPSD	COSMIC	8.808	Up-regulation
CMGC_CDK_CDK5_CDK5_ST	Q3V6T2	CCDC88A	Q00535	CDK5	T1774	P1773L	1773	Missense	proximal	-1	no	16.890	16.885	EPSD	COSMIC	8.808	Down-regulation
CMGC_CDK_CDK5_CDK5_ST	Q3V6T2	CCDC88A	Q00535	CDK5	T1774	A1770V	1770	Missense	distal	-4	no	16.890	17.309	EPSD	COSMIC	8.808	Up-regulation
CMGC_CDK_CDK5_CDK5_ST	Q3V6T2	CCDC88A	Q00535	CDK5	T1774	K1780E	1780	Missense	distal	6	no	16.890	16.871	EPSD	COSMIC	8.808	Down-regulation
CMGC_CDK_CDK5_CDK5_ST	Q3V6T2	CCDC88A	Q00535	CDK5	T1777	P1775S	1775	Missense	proximal	-2	no	10.167	10.069	EPSD	COSMIC	8.808	Down-regulation
CMGC_CDK_CDK5_CDK5_ST	Q3V6T2	CCDC88A	Q00535	CDK5	T1777	I1781M	1781	Missense	distal	4	no	10.167	10.116	EPSD	COSMIC	8.808	Down-regulation
CMGC_CDK_CDK5_CDK5_ST	Q3V6T2	CCDC88A	Q00535	CDK5	T1777	G1776S	1776	Missense	proximal	-1	no	10.167	10.172	EPSD	COSMIC	8.808	Up-regulation
CMGC_CDK_CDK5_CDK5_ST	Q3V6T2	CCDC88A	Q00535	CDK5	T1777	A1770T	1770	Missense	distal	-7	no	10.167	10.207	EPSD	COSMIC	8.808	Up-regulation
CMGC_CDK_CDK5_CDK5_ST	Q3V6T2	CCDC88A	Q00535	CDK5	T1777	P1773L	1773	Missense	distal	-4	no	10.167	9.694	EPSD	COSMIC	8.808	Down-regulation
CMGC_CDK_CDK5_CDK5_ST	Q3V6T2	CCDC88A	Q00535	CDK5	T1777	P1773T	1773	Missense	distal	-4	no	10.167	10.011	EPSD	COSMIC	8.808	Down-regulation
CMGC_CDK_CDK5_CDK5_ST	Q3V6T2	CCDC88A	Q00535	CDK5	T1777	A1770V	1770	Missense	distal	-7	no	10.167	10.203	EPSD	COSMIC	8.808	Up-regulation
CMGC_CDK_CDK5_CDK5_ST	Q3V6T2	CCDC88A	Q00535	CDK5	T1777	K1780E	1780	Missense	distal	3	no	10.167	7.881	EPSD	COSMIC	8.808	Loss
CMGC_CDK_CDK5_CDK5_ST	Q3V6T2	CCDC88A	Q00535	CDK5	S1790	R1791K	1791	Missense	proximal	1	no	8.818	-0.413	EPSD	COSMIC	8.808	Loss
CMGC_CDK_CDK5_CDK5_ST	Q3V6T2	CCDC88A	Q00535	CDK5	S1790	S1796C	1796	Missense	distal	6	no	8.818	8.801	EPSD	COSMIC	8.808	Loss
CMGC_CDK_CDK5_CDK5_ST	Q3V6T2	CCDC88A	Q00535	CDK5	S1790	S1787Y	1787	Missense	distal	-3	no	8.818	8.761	EPSD	COSMIC	8.808	Loss
CMGC_CDK_CDK5_CDK5_ST	Q3V6T2	CCDC88A	Q00535	CDK5	S1790	S1787F	1787	Missense	distal	-3	no	8.818	8.740	EPSD	COSMIC	8.808	Loss
CMGC_CDK_CDK5_CDK5_ST	Q3V6T2	CCDC88A	Q00535	CDK5	S1837	S1837Y	1837	Missense	central	0	yes	16.919	0.000	EPSD	COSMIC	8.808	Loss
CMGC_CDK_CDK5_CDK5_ST	Q3V6T2	CCDC88A	Q00535	CDK5	S1837	P1838A	1838	Missense	proximal	1	no	16.919	5.893	EPSD	COSMIC	8.808	Loss
CMGC_CDK_CDK5_CDK5_ST	Q3V6T2	CCDC88A	Q00535	CDK5	S1837	D1843Y	1843	Missense	distal	6	no	16.919	16.916	EPSD	COSMIC	8.808	Down-regulation
CMGC_CDK_CDK5_CDK5_ST	Q3V6T2	CCDC88A	Q00535	CDK5	S1837	V1835G	1835	Missense	proximal	-2	no	16.919	16.636	EPSD	COSMIC	8.808	Down-regulation
CMGC_CDK_CDK5_CDK5_ST	Q3V6T2	CCDC88A	Q00535	CDK5	S1837	P1839A	1839	Missense	proximal	2	no	16.919	16.807	EPSD	COSMIC	8.808	Down-regulation
CMGC_CDK_CDK5_CDK5_ST	Q3V6T2	CCDC88A	Q00535	CDK5	S1837	A1840V	1840	Missense	distal	3	no	16.919	17.171	EPSD	COSMIC	8.808	Up-regulation
CMGC_CDK_CDK5_CDK5_ST	P14416	DRD2	Q00535	CDK5	S19	Q16K	16	Missense	distal	-3	no	9.063	9.109	EPSD	COSMIC	8.808	Up-regulation
CMGC_CDK_CDK5_CDK5_ST	P14416	DRD2	Q00535	CDK5	S19	P21R	21	Missense	proximal	2	no	9.063	9.145	EPSD	COSMIC	8.808	Up-regulation
CMGC_CDK_CDK5_CDK5_ST	P14416	DRD2	Q00535	CDK5	S296	P299L	299	Missense	distal	3	no	17.780	16.708	EPSD	COSMIC	8.808	Down-regulation
CMGC_CDK_CDK5_CDK5_ST	P14416	DRD2	Q00535	CDK5	S296	P299H	299	Missense	distal	3	no	17.780	18.159	EPSD	COSMIC	8.808	Up-regulation
CMGC_CDK_CDK5_CDK5_ST	P14416	DRD2	Q00535	CDK5	S296	H302N	302	Missense	distal	6	no	17.780	17.779	EPSD	COSMIC	8.808	Down-regulation
CMGC_CDK_CDK5_CDK5_ST	P14416	DRD2	Q00535	CDK5	S296	P299A	299	Missense	distal	3	no	17.780	17.536	EPSD	COSMIC;GDSC;CCLE	8.808	Down-regulation
CMGC_CDK_CDK5_CDK5_ST	P14416	DRD2	Q00535	CDK5	S296	S296R	296	Missense	central	0	yes	17.780	0.000	EPSD	COSMIC	8.808	Loss
CMGC_CDK_CDK5_CDK5_ST	P14416	DRD2	Q00535	CDK5	S296	R294L	294	Missense	proximal	-2	no	17.780	17.420	EPSD	COSMIC	8.808	Down-regulation
CMGC_CDK_CDK5_CDK5_ST	P14416	DRD2	Q00535	CDK5	S296	R294W	294	Missense	proximal	-2	no	17.780	17.407	EPSD	COSMIC	8.808	Down-regulation
CMGC_CDK_CDK5_CDK5_ST	P14416	DRD2	Q00535	CDK5	S301	H302N	302	Missense	proximal	1	no	-0.184	9.089	EPSD	COSMIC	8.808	Gain
CMGC_CDK_CDK5_CDK5_ST	P14416	DRD2	Q00535	CDK5	S321	G314S	314	Missense	distal	-7	no	20.081	20.133	PhosphoSitePlus	COSMIC	8.808	Up-regulation
CMGC_CDK_CDK5_CDK5_ST	P14416	DRD2	Q00535	CDK5	S321	K327R	327	Missense	distal	6	no	20.081	20.079	PhosphoSitePlus	COSMIC	8.808	Down-regulation
CMGC_CDK_CDK5_CDK5_ST	P14416	DRD2	Q00535	CDK5	S359	R360C	360	Missense	proximal	1	no	10.442	-1.285	EPSD	COSMIC	8.808	Loss
CMGC_CDK_CDK5_CDK5_ST	P14416	DRD2	Q00535	CDK5	S359	S354F	354	Missense	distal	-5	no	10.442	10.112	EPSD	COSMIC	8.808	Down-regulation
CMGC_CDK_CDK5_CDK5_ST	P14416	DRD2	Q00535	CDK5	S359	S359G	359	Missense	central	0	yes	10.442	0.000	EPSD	COSMIC	8.808	Loss
CMGC_CDK_CDK5_CDK5_ST	P14416	DRD2	Q00535	CDK5	S359	R360H	360	Missense	proximal	1	no	10.442	0.877	EPSD	COSMIC	8.808	Loss
CMGC_CDK_CDK5_CDK5_ST	Q13136	PPFIA1	Q00535	CDK5	S26	S26Y	26	Missense	central	0	yes	18.306	0.000	EPSD	COSMIC	8.808	Loss
CMGC_CDK_CDK5_CDK5_ST	Q13136	PPFIA1	Q00535	CDK5	S28	S26Y	26	Missense	proximal	-2	no	9.567	9.137	EPSD	COSMIC	8.808	Down-regulation
CMGC_CDK_CDK5_CDK5_ST	Q13136	PPFIA1	Q00535	CDK5	S150	V154L	154	Missense	distal	4	no	18.030	17.967	EPSD	COSMIC	8.808	Down-regulation
CMGC_CDK_CDK5_CDK5_ST	Q13136	PPFIA1	Q00535	CDK5	S458	S456L	456	Missense	proximal	-2	no	10.121	9.805	EPSD	COSMIC	8.808	Down-regulation
CMGC_CDK_CDK5_CDK5_ST	Q13136	PPFIA1	Q00535	CDK5	S458	D452N	452	Missense	distal	-6	no	10.121	10.160	EPSD	COSMIC	8.808	Up-regulation
CMGC_CDK_CDK5_CDK5_ST	Q13136	PPFIA1	Q00535	CDK5	S485	K488T	488	Missense	distal	3	no	8.846	7.665	EPSD	COSMIC	8.808	Loss
CMGC_CDK_CDK5_CDK5_ST	Q13136	PPFIA1	Q00535	CDK5	S618	L611F	611	Missense	distal	-7	no	18.198	18.170	EPSD	COSMIC	8.808	Down-regulation
CMGC_CDK_CDK5_CDK5_ST	Q13136	PPFIA1	Q00535	CDK5	S693	S687F	687	Missense	distal	-6	no	18.047	17.874	EPSD	COSMIC	8.808	Down-regulation
CMGC_CDK_CDK5_CDK5_ST	Q13136	PPFIA1	Q00535	CDK5	S741	P742S	742	Missense	proximal	1	no	18.294	6.393	EPSD	COSMIC	8.808	Loss
CMGC_CDK_CDK5_CDK5_ST	Q13136	PPFIA1	Q00535	CDK5	S741	S741F	741	Missense	central	0	yes	18.294	0.000	EPSD	COSMIC	8.808	Loss
CMGC_CDK_CDK5_CDK5_ST	Q13136	PPFIA1	Q00535	CDK5	S745	P742S	742	Missense	distal	-3	no	18.291	18.286	EPSD	COSMIC	8.808	Down-regulation
CMGC_CDK_CDK5_CDK5_ST	Q13136	PPFIA1	Q00535	CDK5	S745	S741F	741	Missense	distal	-4	no	18.291	17.130	EPSD	COSMIC	8.808	Down-regulation
CMGC_CDK_CDK5_CDK5_ST	Q13136	PPFIA1	Q00535	CDK5	S782	S789N	789	Missense	distal	7	no	8.874	8.870	EPSD	COSMIC	8.808	Down-regulation
CMGC_CDK_CDK5_CDK5_ST	Q13136	PPFIA1	Q00535	CDK5	S782	N788H	788	Missense	distal	6	no	8.874	8.875	EPSD	COSMIC	8.808	Up-regulation
CMGC_CDK_CDK5_CDK5_ST	Q13136	PPFIA1	Q00535	CDK5	S787	S789N	789	Missense	proximal	2	no	9.029	8.983	EPSD	COSMIC	8.808	Down-regulation
CMGC_CDK_CDK5_CDK5_ST	Q13136	PPFIA1	Q00535	CDK5	S787	N788H	788	Missense	proximal	1	no	9.029	-0.245	EPSD	COSMIC	8.808	Loss
CMGC_CDK_CDK5_CDK5_ST	Q13136	PPFIA1	Q00535	CDK5	S787	Q791K	791	Missense	distal	4	no	9.029	9.123	EPSD	COSMIC	8.808	Up-regulation
CMGC_CDK_CDK5_CDK5_ST	Q13136	PPFIA1	Q00535	CDK5	S790	S789N	789	Missense	proximal	-1	no	9.059	9.057	EPSD	COSMIC	8.808	Down-regulation
CMGC_CDK_CDK5_CDK5_ST	Q13136	PPFIA1	Q00535	CDK5	S790	H795L	795	Missense	distal	5	no	9.059	8.915	EPSD	COSMIC	8.808	Down-regulation
CMGC_CDK_CDK5_CDK5_ST	Q13136	PPFIA1	Q00535	CDK5	S790	N788H	788	Missense	proximal	-2	no	9.059	8.955	EPSD	COSMIC	8.808	Down-regulation
CMGC_CDK_CDK5_CDK5_ST	Q13136	PPFIA1	Q00535	CDK5	S790	Q791K	791	Missense	proximal	1	no	9.059	-0.143	EPSD	COSMIC	8.808	Loss
CMGC_CDK_CDK5_CDK5_ST	Q13136	PPFIA1	Q00535	CDK5	S946	S943L	943	Missense	distal	-3	no	17.076	17.021	EPSD	COSMIC	8.808	Down-regulation
CMGC_CDK_CDK5_CDK5_ST	Q13136	PPFIA1	Q00535	CDK5	S946	P947L	947	Missense	proximal	1	no	17.076	5.126	EPSD	COSMIC	8.808	Loss
CMGC_CDK_CDK5_CDK5_ST	Q13136	PPFIA1	Q00535	CDK5	S953	P947L	947	Missense	distal	-6	no	8.850	8.767	EPSD	COSMIC	8.808	Loss
CMGC_CDK_CDK5_CDK5_ST	Q13136	PPFIA1	Q00535	CDK5	S1172	M1170T	1170	Missense	proximal	-2	no	17.444	17.878	EPSD	COSMIC	8.808	Up-regulation
CMGC_CDK_CDK5_CDK5_ST	Q8IWU2	LMTK2	Q00535	CDK5	T90	P97L	97	Missense	distal	7	no	16.399	16.387	EPSD	COSMIC;GDSC;CCLE	8.808	Down-regulation
CMGC_CDK_CDK5_CDK5_ST	Q8IWU2	LMTK2	Q00535	CDK5	S438	S439P	439	Missense	proximal	1	no	5.860	17.761	EPSD	COSMIC	8.808	Gain
CMGC_CDK_CDK5_CDK5_ST	Q8IWU2	LMTK2	Q00535	CDK5	S439	A443E	443	Missense	distal	4	no	8.810	8.819	EPSD	COSMIC	8.808	Up-regulation
CMGC_CDK_CDK5_CDK5_ST	Q8IWU2	LMTK2	Q00535	CDK5	S439	P445S	445	Missense	distal	6	no	8.810	8.811	EPSD	COSMIC	8.808	Up-regulation
CMGC_CDK_CDK5_CDK5_ST	Q8IWU2	LMTK2	Q00535	CDK5	S439	S439P	439	Missense	central	0	yes	8.810	0.000	EPSD	COSMIC	8.808	Loss
CMGC_CDK_CDK5_CDK5_ST	Q8IWU2	LMTK2	Q00535	CDK5	S439	D437G	437	Missense	proximal	-2	no	8.810	8.680	EPSD	COSMIC	8.808	Loss
CMGC_CDK_CDK5_CDK5_ST	Q8IWU2	LMTK2	Q00535	CDK5	S587	A591S	591	Missense	distal	4	no	8.977	9.039	EPSD	COSMIC	8.808	Up-regulation
CMGC_CDK_CDK5_CDK5_ST	Q8IWU2	LMTK2	Q00535	CDK5	S587	T582S	582	Missense	distal	-5	no	8.977	9.002	EPSD	COSMIC	8.808	Up-regulation
CMGC_CDK_CDK5_CDK5_ST	Q8IWU2	LMTK2	Q00535	CDK5	S587	G583D	583	Missense	distal	-4	no	8.977	9.142	EPSD	COSMIC;GDSC;CCLE	8.808	Up-regulation
CMGC_CDK_CDK5_CDK5_ST	Q8IWU2	LMTK2	Q00535	CDK5	S587	A591T	591	Missense	distal	4	no	8.977	9.037	EPSD	COSMIC	8.808	Up-regulation
CMGC_CDK_CDK5_CDK5_ST	Q8IWU2	LMTK2	Q00535	CDK5	S630	F636L	636	Missense	distal	6	no	18.284	18.289	EPSD	COSMIC	8.808	Up-regulation
CMGC_CDK_CDK5_CDK5_ST	Q8IWU2	LMTK2	Q00535	CDK5	S810	E812D	812	Missense	proximal	2	no	18.413	18.409	EPSD	COSMIC	8.808	Down-regulation
CMGC_CDK_CDK5_CDK5_ST	Q8IWU2	LMTK2	Q00535	CDK5	S810	S810F	810	Missense	central	0	yes	18.413	0.000	EPSD	COSMIC	8.808	Loss
CMGC_CDK_CDK5_CDK5_ST	Q8IWU2	LMTK2	Q00535	CDK5	T825	P826A	826	Missense	proximal	1	no	18.282	7.256	EPSD	COSMIC	8.808	Loss
CMGC_CDK_CDK5_CDK5_ST	Q8IWU2	LMTK2	Q00535	CDK5	S886	L879M	879	Missense	distal	-7	no	17.602	17.586	EPSD	COSMIC	8.808	Down-regulation
CMGC_CDK_CDK5_CDK5_ST	Q8IWU2	LMTK2	Q00535	CDK5	T996	P997Q	997	Missense	proximal	1	no	16.692	7.716	EPSD	COSMIC	8.808	Loss
CMGC_CDK_CDK5_CDK5_ST	Q8IWU2	LMTK2	Q00535	CDK5	T996	P992Q	992	Missense	distal	-4	no	16.692	16.567	EPSD	COSMIC	8.808	Down-regulation
CMGC_CDK_CDK5_CDK5_ST	Q8IWU2	LMTK2	Q00535	CDK5	T996	V1003A	1003	Missense	distal	7	no	16.692	16.684	EPSD	COSMIC	8.808	Down-regulation
CMGC_CDK_CDK5_CDK5_ST	Q8IWU2	LMTK2	Q00535	CDK5	T1088	G1084S	1084	Missense	distal	-4	no	17.139	17.980	EPSD	COSMIC	8.808	Up-regulation
CMGC_CDK_CDK5_CDK5_ST	Q8IWU2	LMTK2	Q00535	CDK5	T1088	P1089T	1089	Missense	proximal	1	no	17.139	6.652	EPSD	COSMIC	8.808	Loss
CMGC_CDK_CDK5_CDK5_ST	Q8IWU2	LMTK2	Q00535	CDK5	S1124	E1118G	1118	Missense	distal	-6	no	17.619	17.611	EPSD	COSMIC	8.808	Down-regulation
CMGC_CDK_CDK5_CDK5_ST	Q8IWU2	LMTK2	Q00535	CDK5	S1124	P1125T	1125	Missense	proximal	1	no	17.619	7.132	EPSD	COSMIC	8.808	Loss
CMGC_CDK_CDK5_CDK5_ST	Q8IWU2	LMTK2	Q00535	CDK5	S1124	E1118D	1118	Missense	distal	-6	no	17.619	17.609	EPSD	COSMIC	8.808	Down-regulation
CMGC_CDK_CDK5_CDK5_ST	Q8IWU2	LMTK2	Q00535	CDK5	S1124	S1126F	1126	Missense	proximal	2	no	17.619	17.409	EPSD	COSMIC	8.808	Down-regulation
CMGC_CDK_CDK5_CDK5_ST	Q8IWU2	LMTK2	Q00535	CDK5	S1323	P1317L	1317	Missense	distal	-6	no	8.852	8.769	EPSD	COSMIC	8.808	Loss
CMGC_CDK_CDK5_CDK5_ST	Q8IWU2	LMTK2	Q00535	CDK5	S1323	G1327R	1327	Missense	distal	4	no	8.852	8.920	EPSD	COSMIC	8.808	Up-regulation
CMGC_CDK_CDK5_CDK5_ST	Q8IWU2	LMTK2	Q00535	CDK5	S1323	I1320M	1320	Missense	distal	-3	no	8.852	8.811	EPSD	COSMIC	8.808	Down-regulation
CMGC_CDK_CDK5_CDK5_ST	Q8IWU2	LMTK2	Q00535	CDK5	S1397	S1401N	1401	Missense	distal	4	no	17.537	17.506	EPSD	COSMIC	8.808	Down-regulation
CMGC_CDK_CDK5_CDK5_ST	Q8IWU2	LMTK2	Q00535	CDK5	S1450	S1457R	1457	Missense	distal	7	no	18.668	18.670	PhosphoSitePlus	COSMIC	8.808	Up-regulation
CMGC_CDK_CDK5_CDK5_ST	Q8IWU2	LMTK2	Q00535	CDK5	S1450	T1445S	1445	Missense	distal	-5	no	18.668	18.694	PhosphoSitePlus	COSMIC;GDSC;CCLE	8.808	Up-regulation
CMGC_CDK_CDK5_CDK5_ST	Q8IWU2	LMTK2	Q00535	CDK5	S1469	P1463L	1463	Missense	distal	-6	no	9.433	9.350	EPSD	COSMIC;GDSC	8.808	Down-regulation
CMGC_CDK_CDK5_CDK5_ST	P47989	XDH	Q00535	CDK5	S192	L191F	191	Missense	proximal	-1	no	17.464	17.462	EPSD	COSMIC	8.808	Down-regulation
CMGC_CDK_CDK5_CDK5_ST	P47989	XDH	Q00535	CDK5	S192	D186G	186	Missense	distal	-6	no	17.464	17.467	EPSD	COSMIC	8.808	Up-regulation
CMGC_CDK_CDK5_CDK5_ST	P47989	XDH	Q00535	CDK5	S194	L191F	191	Missense	distal	-3	no	9.323	9.301	EPSD	COSMIC	8.808	Down-regulation
CMGC_CDK_CDK5_CDK5_ST	P47989	XDH	Q00535	CDK5	T202	T207N	207	Missense	distal	5	no	16.353	16.289	EPSD	COSMIC	8.808	Down-regulation
CMGC_CDK_CDK5_CDK5_ST	P47989	XDH	Q00535	CDK5	T202	P206S	206	Missense	distal	4	no	16.353	16.355	EPSD	COSMIC	8.808	Up-regulation
CMGC_CDK_CDK5_CDK5_ST	P47989	XDH	Q00535	CDK5	T222	E215K	215	Missense	distal	-7	no	18.965	19.027	PhosphoSitePlus	COSMIC	8.808	Up-regulation
CMGC_CDK_CDK5_CDK5_ST	P47989	XDH	Q00535	CDK5	T222	R224W	224	Missense	proximal	2	no	18.965	18.773	PhosphoSitePlus	COSMIC	8.808	Down-regulation
CMGC_CDK_CDK5_CDK5_ST	P47989	XDH	Q00535	CDK5	S356	S359T	359	Missense	distal	3	no	17.577	18.134	EPSD	COSMIC	8.808	Up-regulation
CMGC_CDK_CDK5_CDK5_ST	P47989	XDH	Q00535	CDK5	S356	G349E	349	Missense	distal	-7	no	17.577	17.584	EPSD	COSMIC	8.808	Up-regulation
CMGC_CDK_CDK5_CDK5_ST	P47989	XDH	Q00535	CDK5	S356	G349V	349	Missense	distal	-7	no	17.577	17.611	EPSD	COSMIC	8.808	Up-regulation
CMGC_CDK_CDK5_CDK5_ST	P47989	XDH	Q00535	CDK5	S399	I403M	403	Missense	distal	4	no	17.108	17.056	EPSD	COSMIC	8.808	Down-regulation
CMGC_CDK_CDK5_CDK5_ST	P47989	XDH	Q00535	CDK5	T804	G798C	798	Missense	distal	-6	no	8.916	8.866	EPSD	COSMIC;GDSC;CCLE	8.808	Down-regulation
CMGC_CDK_CDK5_CDK5_ST	P47989	XDH	Q00535	CDK5	T804	G797A	797	Missense	distal	-7	no	8.916	8.915	EPSD	COSMIC	8.808	Down-regulation
CMGC_CDK_CDK5_CDK5_ST	P47989	XDH	Q00535	CDK5	S1299	R1296W	1296	Missense	distal	-3	no	17.607	17.554	EPSD	COSMIC	8.808	Down-regulation
CMGC_CDK_CDK5_CDK5_ST	P47989	XDH	Q00535	CDK5	S1299	D1298Y	1298	Missense	proximal	-1	no	17.607	17.605	EPSD	COSMIC	8.808	Down-regulation
CMGC_CDK_CDK5_CDK5_ST	P47989	XDH	Q00535	CDK5	S1299	E1304K	1304	Missense	distal	5	no	17.607	17.858	EPSD	COSMIC	8.808	Up-regulation
CMGC_CDK_CDK5_CDK5_ST	P47989	XDH	Q00535	CDK5	S1299	P1300S	1300	Missense	proximal	1	no	17.607	5.706	EPSD	COSMIC;GDSC;CCLE	8.808	Loss
CMGC_CDK_CDK5_CDK5_ST	Q12778	FOXO1	Q00535	CDK5	T24	W25R	25	Missense	proximal	1	no	-1.023	8.835	EPSD	COSMIC	8.808	Gain
CMGC_CDK_CDK5_CDK5_ST	Q12778	FOXO1	Q00535	CDK5	S249	G243S	243	Missense	distal	-6	no	18.860	18.955	PhosphoSitePlus	COSMIC	8.808	Up-regulation
CMGC_CDK_CDK5_CDK5_ST	Q12778	FOXO1	Q00535	CDK5	S249	G243V	243	Missense	distal	-6	no	18.860	18.910	PhosphoSitePlus	COSMIC	8.808	Up-regulation
CMGC_CDK_CDK5_CDK5_ST	Q12778	FOXO1	Q00535	CDK5	S287	S287N	287	Missense	central	0	yes	17.004	0.000	EPSD	COSMIC	8.808	Loss
CMGC_CDK_CDK5_CDK5_ST	Q12778	FOXO1	Q00535	CDK5	S298	H302Y	302	Missense	distal	4	no	18.003	17.940	EPSD	COSMIC	8.808	Down-regulation
CMGC_CDK_CDK5_CDK5_ST	Q12778	FOXO1	Q00535	CDK5	S383	S382L	382	Missense	proximal	-1	no	17.450	17.444	EPSD	COSMIC;GDSC	8.808	Down-regulation
CMGC_CDK_CDK5_CDK5_ST	Q12778	FOXO1	Q00535	CDK5	S383	L380I	380	Missense	distal	-3	no	17.450	17.481	EPSD	COSMIC	8.808	Up-regulation
CMGC_CDK_CDK5_CDK5_ST	Q12778	FOXO1	Q00535	CDK5	S383	S390L	390	Missense	distal	7	no	17.450	17.438	EPSD	COSMIC	8.808	Down-regulation
CMGC_CDK_CDK5_CDK5_ST	Q12778	FOXO1	Q00535	CDK5	S383	S386P	386	Missense	distal	3	no	17.450	17.470	EPSD	COSMIC	8.808	Up-regulation
CMGC_CDK_CDK5_CDK5_ST	Q12778	FOXO1	Q00535	CDK5	S394	S393Y	393	Missense	proximal	-1	no	18.794	18.788	EPSD	COSMIC	8.808	Down-regulation
CMGC_CDK_CDK5_CDK5_ST	Q12778	FOXO1	Q00535	CDK5	S394	S390L	390	Missense	distal	-4	no	18.794	17.975	EPSD	COSMIC	8.808	Down-regulation
CMGC_CDK_CDK5_CDK5_ST	Q12778	FOXO1	Q00535	CDK5	T402	Y405C	405	Missense	distal	3	no	16.071	15.962	EPSD	COSMIC	8.808	Down-regulation
CMGC_CDK_CDK5_CDK5_ST	Q12778	FOXO1	Q00535	CDK5	S416	P417S	417	Missense	proximal	1	no	17.205	5.304	EPSD	COSMIC	8.808	Loss
CMGC_CDK_CDK5_CDK5_ST	Q12778	FOXO1	Q00535	CDK5	S418	P417S	417	Missense	proximal	-1	no	16.175	16.176	EPSD	COSMIC	8.808	Up-regulation
CMGC_CDK_CDK5_CDK5_ST	Q12778	FOXO1	Q00535	CDK5	S432	P438H	438	Missense	distal	6	no	18.004	18.000	EPSD	COSMIC	8.808	Down-regulation
CMGC_CDK_CDK5_CDK5_ST	Q12778	FOXO1	Q00535	CDK5	S432	S432N	432	Missense	central	0	yes	18.004	0.000	EPSD	COSMIC	8.808	Loss
CMGC_CDK_CDK5_CDK5_ST	Q12778	FOXO1	Q00535	CDK5	S432	I439V	439	Missense	distal	7	no	18.004	18.007	EPSD	COSMIC	8.808	Up-regulation
CMGC_CDK_CDK5_CDK5_ST	Q12778	FOXO1	Q00535	CDK5	S432	G427V	427	Missense	distal	-5	no	18.004	18.118	EPSD	COSMIC	8.808	Up-regulation
CMGC_CDK_CDK5_CDK5_ST	Q12778	FOXO1	Q00535	CDK5	S470	D469A	469	Missense	proximal	-1	no	17.499	17.498	EPSD	COSMIC	8.808	Down-regulation
CMGC_CDK_CDK5_CDK5_ST	Q12778	FOXO1	Q00535	CDK5	S470	K463N	463	Missense	distal	-7	no	17.499	17.456	EPSD	COSMIC	8.808	Down-regulation
CMGC_CDK_CDK5_CDK5_ST	Q12778	FOXO1	Q00535	CDK5	S470	N474D	474	Missense	distal	4	no	17.499	17.469	EPSD	COSMIC	8.808	Down-regulation
CMGC_CDK_CDK5_CDK5_ST	Q12778	FOXO1	Q00535	CDK5	T478	P482A	482	Missense	distal	4	no	17.043	16.982	EPSD	COSMIC	8.808	Down-regulation
CMGC_CDK_CDK5_CDK5_ST	Q12778	FOXO1	Q00535	CDK5	T478	P482H	482	Missense	distal	4	no	17.043	17.022	EPSD	COSMIC	8.808	Down-regulation
CMGC_CDK_CDK5_CDK5_ST	Q12778	FOXO1	Q00535	CDK5	T478	P479S	479	Missense	proximal	1	no	17.043	5.142	EPSD	COSMIC	8.808	Loss
CMGC_CDK_CDK5_CDK5_ST	Q12778	FOXO1	Q00535	CDK5	T478	N474D	474	Missense	distal	-4	no	17.043	16.879	EPSD	COSMIC	8.808	Down-regulation
CMGC_CDK_CDK5_CDK5_ST	P62136	PPP1CA	Q00535	CDK5	S22	G25C	25	Missense	distal	3	no	9.991	9.077	EPSD	COSMIC	8.808	Down-regulation
CMGC_CDK_CDK5_CDK5_ST	P62136	PPP1CA	Q00535	CDK5	S22	R23W	23	Missense	proximal	1	no	9.991	0.133	EPSD	COSMIC	8.808	Loss
CMGC_CDK_CDK5_CDK5_ST	P62136	PPP1CA	Q00535	CDK5	S22	Q20H	20	Missense	proximal	-2	no	9.991	9.867	EPSD	COSMIC	8.808	Down-regulation
CMGC_CDK_CDK5_CDK5_ST	P62136	PPP1CA	Q00535	CDK5	S22	G21C	21	Missense	proximal	-1	no	9.991	9.989	EPSD	COSMIC	8.808	Down-regulation
CMGC_CDK_CDK5_CDK5_ST	P62136	PPP1CA	Q00535	CDK5	S177	F170C	170	Missense	distal	-7	no	16.287	16.300	EPSD	COSMIC	8.808	Up-regulation
CMGC_CDK_CDK5_CDK5_ST	P62136	PPP1CA	Q00535	CDK5	S177	P178Q	178	Missense	proximal	1	no	16.287	7.312	EPSD	COSMIC	8.808	Loss
CMGC_CDK_CDK5_CDK5_ST	P62136	PPP1CA	Q00535	CDK5	S177	P178L	178	Missense	proximal	1	no	16.287	4.338	EPSD	COSMIC	8.808	Loss
CMGC_CDK_CDK5_CDK5_ST	P62136	PPP1CA	Q00535	CDK5	T320	P321T	321	Missense	proximal	1	no	19.275	8.788	PhosphoSitePlus	COSMIC	8.808	Loss
CMGC_CDK_CDK5_CDK5_ST	P62136	PPP1CA	Q00535	CDK5	T320	P322S	322	Missense	proximal	2	no	19.275	19.258	PhosphoSitePlus	COSMIC	8.808	Down-regulation
CMGC_CDK_CDK5_CDK5_ST	P62136	PPP1CA	Q00535	CDK5	T320	R323H	323	Missense	distal	3	no	19.275	18.256	PhosphoSitePlus	COSMIC	8.808	Down-regulation
CMGC_CDK_CDK5_CDK5_ST	P62136	PPP1CA	Q00535	CDK5	T320	A326T	326	Missense	distal	6	no	19.275	19.287	PhosphoSitePlus	COSMIC	8.808	Up-regulation
CMGC_CDK_CDK5_CDK5_ST	P62136	PPP1CA	Q00535	CDK5	T320	G315W	315	Missense	distal	-5	no	19.275	19.268	PhosphoSitePlus	COSMIC	8.808	Down-regulation
CMGC_CDK_CDK5_CDK5_ST	Q9NZ72	STMN3	Q00535	CDK5	S6	K11N	11	Missense	distal	5	no	8.996	8.794	EPSD	COSMIC	8.808	Loss
CMGC_CDK_CDK5_CDK5_ST	Q9NZ72	STMN3	Q00535	CDK5	S6	S3I	3	Missense	distal	-3	no	8.996	8.972	EPSD	COSMIC	8.808	Down-regulation
CMGC_CDK_CDK5_CDK5_ST	Q9NZ72	STMN3	Q00535	CDK5	S60	D63H	63	Missense	distal	3	no	17.217	18.230	EPSD	COSMIC	8.808	Up-regulation
CMGC_CDK_CDK5_CDK5_ST	Q9NZ72	STMN3	Q00535	CDK5	S60	D63N	63	Missense	distal	3	no	17.217	17.636	EPSD	COSMIC	8.808	Up-regulation
CMGC_CDK_CDK5_CDK5_ST	Q9NZ72	STMN3	Q00535	CDK5	S60	D63E	63	Missense	distal	3	no	17.217	17.282	EPSD	COSMIC	8.808	Up-regulation
CMGC_CDK_CDK5_CDK5_ST	Q9NZ72	STMN3	Q00535	CDK5	S60	E55K	55	Missense	distal	-5	no	17.217	17.507	EPSD	COSMIC	8.808	Up-regulation
CMGC_CDK_CDK5_CDK5_ST	Q9NZ72	STMN3	Q00535	CDK5	S65	P69H	69	Missense	distal	4	no	17.890	17.869	EPSD	COSMIC;GDSC;CCLE	8.808	Down-regulation
CMGC_CDK_CDK5_CDK5_ST	Q9NZ72	STMN3	Q00535	CDK5	S65	D63H	63	Missense	proximal	-2	no	17.890	17.907	EPSD	COSMIC	8.808	Up-regulation
CMGC_CDK_CDK5_CDK5_ST	Q9NZ72	STMN3	Q00535	CDK5	S65	D63N	63	Missense	proximal	-2	no	17.890	18.011	EPSD	COSMIC	8.808	Up-regulation
CMGC_CDK_CDK5_CDK5_ST	Q9NZ72	STMN3	Q00535	CDK5	S65	D63E	63	Missense	proximal	-2	no	17.890	17.782	EPSD	COSMIC	8.808	Down-regulation
CMGC_CDK_CDK5_CDK5_ST	Q9NZ72	STMN3	Q00535	CDK5	S65	S72F	72	Missense	distal	7	no	17.890	17.872	EPSD	COSMIC	8.808	Down-regulation
CMGC_CDK_CDK5_CDK5_ST	Q9NZ72	STMN3	Q00535	CDK5	S68	P69H	69	Missense	proximal	1	no	17.056	-1.456	PhosphoSitePlus;EPSD	COSMIC;GDSC;CCLE	8.808	Loss
CMGC_CDK_CDK5_CDK5_ST	Q9NZ72	STMN3	Q00535	CDK5	S68	D63H	63	Missense	distal	-5	no	17.056	17.129	PhosphoSitePlus;EPSD	COSMIC	8.808	Up-regulation
CMGC_CDK_CDK5_CDK5_ST	Q9NZ72	STMN3	Q00535	CDK5	S68	D63N	63	Missense	distal	-5	no	17.056	17.130	PhosphoSitePlus;EPSD	COSMIC	8.808	Up-regulation
CMGC_CDK_CDK5_CDK5_ST	Q9NZ72	STMN3	Q00535	CDK5	S68	D63E	63	Missense	distal	-5	no	17.056	17.046	PhosphoSitePlus;EPSD	COSMIC	8.808	Down-regulation
CMGC_CDK_CDK5_CDK5_ST	Q9NZ72	STMN3	Q00535	CDK5	S68	S72F	72	Missense	distal	4	no	17.056	16.944	PhosphoSitePlus;EPSD	COSMIC	8.808	Down-regulation
CMGC_CDK_CDK5_CDK5_ST	Q9NZ72	STMN3	Q00535	CDK5	S73	P69H	69	Missense	distal	-4	no	19.380	19.045	EPSD;PhosphoSitePlus	COSMIC;GDSC;CCLE	8.808	Down-regulation
CMGC_CDK_CDK5_CDK5_ST	Q9NZ72	STMN3	Q00535	CDK5	S73	S72F	72	Missense	proximal	-1	no	19.380	19.371	EPSD;PhosphoSitePlus	COSMIC	8.808	Down-regulation
CMGC_CDK_CDK5_CDK5_ST	Q13794	PMAIP1	Q00535	CDK5	S13	A17T	17	Missense	distal	4	no	21.053	21.113	PhosphoSitePlus	COSMIC	8.808	Up-regulation
CMGC_CDK_CDK5_CDK5_ST	Q13794	PMAIP1	Q00535	CDK5	S13	R16Q	16	Missense	distal	3	no	21.053	19.250	PhosphoSitePlus	COSMIC	8.808	Down-regulation
CMGC_CDK_CDK5_CDK5_ST	Q13794	PMAIP1	Q00535	CDK5	S13	P14A	14	Missense	proximal	1	no	21.053	10.026	PhosphoSitePlus	COSMIC	8.808	Down-regulation
CMGC_CDK_CDK5_CDK5_ST	Q16643	DBN1	Q00535	CDK5	S73	Y80H	80	Missense	distal	7	no	9.549	9.558	EPSD	COSMIC	8.808	Up-regulation
CMGC_CDK_CDK5_CDK5_ST	Q16643	DBN1	Q00535	CDK5	S73	F67V	67	Missense	distal	-6	no	9.549	9.677	EPSD	COSMIC	8.808	Up-regulation
CMGC_CDK_CDK5_CDK5_ST	Q16643	DBN1	Q00535	CDK5	S73	K79I	79	Missense	distal	6	no	9.549	9.534	EPSD	COSMIC	8.808	Down-regulation
CMGC_CDK_CDK5_CDK5_ST	Q16643	DBN1	Q00535	CDK5	S73	S73F	73	Missense	central	0	yes	9.549	0.000	EPSD	COSMIC	8.808	Loss
CMGC_CDK_CDK5_CDK5_ST	Q16643	DBN1	Q00535	CDK5	S73	A76T	76	Missense	distal	3	no	9.549	10.330	EPSD	COSMIC	8.808	Up-regulation
CMGC_CDK_CDK5_CDK5_ST	Q16643	DBN1	Q00535	CDK5	S142	A138V	138	Missense	distal	-4	no	16.195	16.615	PhosphoSitePlus;EPSD	COSMIC;CCLE	8.808	Up-regulation
CMGC_CDK_CDK5_CDK5_ST	Q16643	DBN1	Q00535	CDK5	S142	R149W	149	Missense	distal	7	no	16.195	16.184	PhosphoSitePlus;EPSD	COSMIC	8.808	Down-regulation
CMGC_CDK_CDK5_CDK5_ST	Q16643	DBN1	Q00535	CDK5	S312	D309Y	309	Missense	distal	-3	no	16.665	16.648	EPSD	COSMIC	8.808	Down-regulation
CMGC_CDK_CDK5_CDK5_ST	Q16643	DBN1	Q00535	CDK5	S312	H316Y	316	Missense	distal	4	no	16.665	16.603	EPSD	COSMIC	8.808	Down-regulation
CMGC_CDK_CDK5_CDK5_ST	Q16643	DBN1	Q00535	CDK5	T331	R336Q	336	Missense	distal	5	no	17.595	17.470	EPSD	COSMIC	8.808	Down-regulation
CMGC_CDK_CDK5_CDK5_ST	Q16643	DBN1	Q00535	CDK5	T331	I333T	333	Missense	proximal	2	no	17.595	17.690	EPSD	COSMIC	8.808	Up-regulation
CMGC_CDK_CDK5_CDK5_ST	Q16643	DBN1	Q00535	CDK5	T331	P334S	334	Missense	distal	3	no	17.595	17.575	EPSD	COSMIC	8.808	Down-regulation
CMGC_CDK_CDK5_CDK5_ST	Q16643	DBN1	Q00535	CDK5	S337	R336Q	336	Missense	proximal	-1	no	17.331	17.329	EPSD	COSMIC	8.808	Down-regulation
CMGC_CDK_CDK5_CDK5_ST	Q16643	DBN1	Q00535	CDK5	S337	S341F	341	Missense	distal	4	no	17.331	17.219	EPSD	COSMIC	8.808	Down-regulation
CMGC_CDK_CDK5_CDK5_ST	Q16643	DBN1	Q00535	CDK5	S337	I333T	333	Missense	distal	-4	no	17.331	17.444	EPSD	COSMIC	8.808	Up-regulation
CMGC_CDK_CDK5_CDK5_ST	Q16643	DBN1	Q00535	CDK5	S337	A344T	344	Missense	distal	7	no	17.331	17.339	EPSD	COSMIC	8.808	Up-regulation
CMGC_CDK_CDK5_CDK5_ST	Q16643	DBN1	Q00535	CDK5	S337	S342G	342	Missense	distal	5	no	17.331	17.227	EPSD	COSMIC	8.808	Down-regulation
CMGC_CDK_CDK5_CDK5_ST	Q16643	DBN1	Q00535	CDK5	S337	P334S	334	Missense	distal	-3	no	17.331	17.325	EPSD	COSMIC	8.808	Down-regulation
CMGC_CDK_CDK5_CDK5_ST	Q16643	DBN1	Q00535	CDK5	T346	A349T	349	Missense	distal	3	no	17.305	18.086	EPSD	COSMIC;CCLE	8.808	Up-regulation
CMGC_CDK_CDK5_CDK5_ST	Q16643	DBN1	Q00535	CDK5	T346	S341F	341	Missense	distal	-5	no	17.305	16.975	EPSD	COSMIC	8.808	Down-regulation
CMGC_CDK_CDK5_CDK5_ST	Q16643	DBN1	Q00535	CDK5	T346	S345A	345	Missense	proximal	-1	no	17.305	17.299	EPSD	COSMIC	8.808	Down-regulation
CMGC_CDK_CDK5_CDK5_ST	Q16643	DBN1	Q00535	CDK5	T346	A344T	344	Missense	proximal	-2	no	17.305	17.543	EPSD	COSMIC	8.808	Up-regulation
CMGC_CDK_CDK5_CDK5_ST	Q16643	DBN1	Q00535	CDK5	T346	S342G	342	Missense	distal	-4	no	17.305	16.464	EPSD	COSMIC	8.808	Down-regulation
CMGC_CDK_CDK5_CDK5_ST	Q16643	DBN1	Q00535	CDK5	T377	P371L	371	Missense	distal	-6	no	8.934	8.851	EPSD	COSMIC	8.808	Down-regulation
CMGC_CDK_CDK5_CDK5_ST	Q16643	DBN1	Q00535	CDK5	T377	P382L	382	Missense	distal	5	no	8.934	8.762	EPSD	COSMIC	8.808	Loss
CMGC_CDK_CDK5_CDK5_ST	Q16643	DBN1	Q00535	CDK5	T377	P380S	380	Missense	distal	3	no	8.934	8.914	EPSD	COSMIC	8.808	Down-regulation
CMGC_CDK_CDK5_CDK5_ST	Q16643	DBN1	Q00535	CDK5	T377	P380L	380	Missense	distal	3	no	8.934	7.862	EPSD	COSMIC	8.808	Loss
CMGC_CDK_CDK5_CDK5_ST	Q16643	DBN1	Q00535	CDK5	S381	P382L	382	Missense	proximal	1	no	16.965	5.015	EPSD	COSMIC	8.808	Loss
CMGC_CDK_CDK5_CDK5_ST	Q16643	DBN1	Q00535	CDK5	S381	P380S	380	Missense	proximal	-1	no	16.965	16.966	EPSD	COSMIC	8.808	Up-regulation
CMGC_CDK_CDK5_CDK5_ST	Q16643	DBN1	Q00535	CDK5	S381	P380L	380	Missense	proximal	-1	no	16.965	16.960	EPSD	COSMIC	8.808	Down-regulation
CMGC_CDK_CDK5_CDK5_ST	Q16643	DBN1	Q00535	CDK5	S416	P411A	411	Missense	distal	-5	no	17.888	17.728	EPSD	COSMIC	8.808	Down-regulation
CMGC_CDK_CDK5_CDK5_ST	Q16643	DBN1	Q00535	CDK5	S416	A409T	409	Missense	distal	-7	no	17.888	17.927	EPSD	COSMIC	8.808	Up-regulation
CMGC_CDK_CDK5_CDK5_ST	Q16643	DBN1	Q00535	CDK5	S416	A409V	409	Missense	distal	-7	no	17.888	17.923	EPSD	COSMIC	8.808	Up-regulation
CMGC_CDK_CDK5_CDK5_ST	Q16643	DBN1	Q00535	CDK5	S416	G413E	413	Missense	distal	-3	no	17.888	17.891	EPSD	COSMIC	8.808	Up-regulation
CMGC_CDK_CDK5_CDK5_ST	Q16643	DBN1	Q00535	CDK5	T497	G501A	501	Missense	distal	4	no	17.058	17.047	EPSD	COSMIC	8.808	Down-regulation
CMGC_CDK_CDK5_CDK5_ST	Q16643	DBN1	Q00535	CDK5	T497	G491D	491	Missense	distal	-6	no	17.058	17.056	EPSD	COSMIC	8.808	Down-regulation
CMGC_CDK_CDK5_CDK5_ST	Q16643	DBN1	Q00535	CDK5	T559	P563L	563	Missense	distal	4	no	16.311	16.230	EPSD	COSMIC	8.808	Down-regulation
CMGC_CDK_CDK5_CDK5_ST	Q16643	DBN1	Q00535	CDK5	T559	S564L	564	Missense	distal	5	no	16.311	16.126	EPSD	COSMIC	8.808	Down-regulation
CMGC_CDK_CDK5_CDK5_ST	Q16643	DBN1	Q00535	CDK5	T559	A565V	565	Missense	distal	6	no	16.311	16.320	EPSD	COSMIC	8.808	Up-regulation
CMGC_CDK_CDK5_CDK5_ST	Q16643	DBN1	Q00535	CDK5	T559	S553F	553	Missense	distal	-6	no	16.311	16.138	EPSD	COSMIC	8.808	Down-regulation
CMGC_CDK_CDK5_CDK5_ST	Q16643	DBN1	Q00535	CDK5	T559	P560R	560	Missense	proximal	1	no	16.311	7.364	EPSD	COSMIC	8.808	Loss
CMGC_CDK_CDK5_CDK5_ST	Q16643	DBN1	Q00535	CDK5	T559	S553P	553	Missense	distal	-6	no	16.311	16.272	EPSD	COSMIC	8.808	Down-regulation
CMGC_CDK_CDK5_CDK5_ST	Q16643	DBN1	Q00535	CDK5	T559	A565D	565	Missense	distal	6	no	16.311	16.312	EPSD	COSMIC	8.808	Up-regulation
CMGC_CDK_CDK5_CDK5_ST	O43526	KCNQ2	Q00535	CDK5	S446	L439M	439	Missense	distal	-7	no	18.229	18.213	PhosphoSitePlus	COSMIC	8.808	Down-regulation
CMGC_CDK_CDK5_CDK5_ST	O43526	KCNQ2	Q00535	CDK5	S446	V450A	450	Missense	distal	4	no	18.229	18.186	PhosphoSitePlus	COSMIC	8.808	Down-regulation
CMGC_CDK_CDK5_CDK5_ST	O43526	KCNQ2	Q00535	CDK5	S446	A452V	452	Missense	distal	6	no	18.229	18.238	PhosphoSitePlus	COSMIC	8.808	Up-regulation
CMGC_CDK_CDK5_CDK5_ST	O43526	KCNQ2	Q00535	CDK5	S446	S445Y	445	Missense	proximal	-1	no	18.229	18.222	PhosphoSitePlus	COSMIC	8.808	Down-regulation
CMGC_CDK_CDK5_CDK5_ST	O43526	KCNQ2	Q00535	CDK5	S446	S446I	446	Missense	central	0	yes	18.229	0.000	PhosphoSitePlus	COSMIC	8.808	Loss
CMGC_CDK_CDK5_CDK5_ST	O43526	KCNQ2	Q00535	CDK5	S457	V450A	450	Missense	distal	-7	no	17.610	17.574	EPSD	COSMIC	8.808	Down-regulation
CMGC_CDK_CDK5_CDK5_ST	O43526	KCNQ2	Q00535	CDK5	S457	A452V	452	Missense	distal	-5	no	17.610	17.735	EPSD	COSMIC	8.808	Up-regulation
CMGC_CDK_CDK5_CDK5_ST	O43526	KCNQ2	Q00535	CDK5	S457	Q459H	459	Missense	proximal	2	no	17.610	17.634	EPSD	COSMIC;GDSC	8.808	Up-regulation
CMGC_CDK_CDK5_CDK5_ST	O43526	KCNQ2	Q00535	CDK5	S466	P467Q	467	Missense	proximal	1	no	17.733	8.757	EPSD	COSMIC	8.808	Loss
CMGC_CDK_CDK5_CDK5_ST	O43526	KCNQ2	Q00535	CDK5	S466	R465H	465	Missense	proximal	-1	no	17.733	17.731	EPSD	COSMIC	8.808	Down-regulation
CMGC_CDK_CDK5_CDK5_ST	O43526	KCNQ2	Q00535	CDK5	S466	Q459H	459	Missense	distal	-7	no	17.733	17.722	EPSD	COSMIC;GDSC	8.808	Down-regulation
CMGC_CDK_CDK5_CDK5_ST	O43526	KCNQ2	Q00535	CDK5	S466	S472C	472	Missense	distal	6	no	17.733	17.717	EPSD	COSMIC	8.808	Down-regulation
CMGC_CDK_CDK5_CDK5_ST	O43526	KCNQ2	Q00535	CDK5	S466	A469T	469	Missense	distal	3	no	17.733	18.514	EPSD	COSMIC	8.808	Up-regulation
CMGC_CDK_CDK5_CDK5_ST	O43526	KCNQ2	Q00535	CDK5	S476	S483G	483	Missense	distal	7	no	20.140	20.131	EPSD	COSMIC	8.808	Down-regulation
CMGC_CDK_CDK5_CDK5_ST	O43526	KCNQ2	Q00535	CDK5	S476	S472C	472	Missense	distal	-4	no	20.140	19.116	EPSD	COSMIC	8.808	Down-regulation
CMGC_CDK_CDK5_CDK5_ST	O43526	KCNQ2	Q00535	CDK5	S476	A469T	469	Missense	distal	-7	no	20.140	20.180	EPSD	COSMIC	8.808	Up-regulation
CMGC_CDK_CDK5_CDK5_ST	O43526	KCNQ2	Q00535	CDK5	S503	F496L	496	Missense	distal	-7	no	8.905	8.933	EPSD	COSMIC	8.808	Up-regulation
CMGC_CDK_CDK5_CDK5_ST	O43526	KCNQ2	Q00535	CDK5	S503	E509Q	509	Missense	distal	6	no	8.905	8.911	EPSD	COSMIC	8.808	Up-regulation
CMGC_CDK_CDK5_CDK5_ST	O43526	KCNQ2	Q00535	CDK5	S503	K499N	499	Missense	distal	-4	no	8.905	8.517	EPSD	COSMIC	8.808	Loss
CMGC_CDK_CDK5_CDK5_ST	O43526	KCNQ2	Q00535	CDK5	S672	A667D	667	Missense	distal	-5	no	17.031	17.047	EPSD	COSMIC	8.808	Up-regulation
CMGC_CDK_CDK5_CDK5_ST	O43526	KCNQ2	Q00535	CDK5	S672	P669S	669	Missense	distal	-3	no	17.031	17.025	EPSD	COSMIC	8.808	Down-regulation
CMGC_CDK_CDK5_CDK5_ST	O43526	KCNQ2	Q00535	CDK5	S672	S672R	672	Missense	central	0	yes	17.031	0.000	EPSD	COSMIC	8.808	Loss
CMGC_CDK_CDK5_CDK5_ST	O43526	KCNQ2	Q00535	CDK5	S672	S672I	672	Missense	central	0	yes	17.031	0.000	EPSD	COSMIC	8.808	Loss
CMGC_CDK_CDK5_CDK5_ST	O43526	KCNQ2	Q00535	CDK5	S672	A667T	667	Missense	distal	-5	no	17.031	17.187	EPSD	COSMIC	8.808	Up-regulation
CMGC_CDK_CDK5_CDK5_ST	O43526	KCNQ2	Q00535	CDK5	S672	R677W	677	Missense	distal	5	no	17.031	16.854	EPSD	COSMIC;GDSC;CCLE	8.808	Down-regulation
CMGC_CDK_CDK5_CDK5_ST	O43526	KCNQ2	Q00535	CDK5	S672	H679Y	679	Missense	distal	7	no	17.031	17.022	EPSD	COSMIC	8.808	Down-regulation
CMGC_CDK_CDK5_CDK5_ST	O43526	KCNQ2	Q00535	CDK5	S672	S676I	676	Missense	distal	4	no	17.031	16.987	EPSD	COSMIC	8.808	Down-regulation
CMGC_CDK_CDK5_CDK5_ST	O43526	KCNQ2	Q00535	CDK5	S672	S672N	672	Missense	central	0	yes	17.031	0.000	EPSD	COSMIC	8.808	Loss
CMGC_CDK_CDK5_CDK5_ST	O43526	KCNQ2	Q00535	CDK5	S731	G727D	727	Missense	distal	-4	no	17.744	17.909	EPSD	COSMIC	8.808	Up-regulation
CMGC_CDK_CDK5_CDK5_ST	O43526	KCNQ2	Q00535	CDK5	S731	R725C	725	Missense	distal	-6	no	17.744	17.592	EPSD	COSMIC	8.808	Down-regulation
CMGC_CDK_CDK5_CDK5_ST	Q9UM11	FZR1	Q00535	CDK5	T32	R29Q	29	Missense	distal	-3	no	17.556	17.530	EPSD	COSMIC;GDSC	8.808	Down-regulation
CMGC_CDK_CDK5_CDK5_ST	Q9UM11	FZR1	Q00535	CDK5	S36	R29Q	29	Missense	distal	-7	no	17.598	17.578	EPSD	COSMIC;GDSC	8.808	Down-regulation
CMGC_CDK_CDK5_CDK5_ST	Q9UM11	FZR1	Q00535	CDK5	S70	S70F	70	Missense	central	0	yes	17.115	0.000	EPSD	COSMIC;GDSC;CCLE	8.808	Loss
CMGC_CDK_CDK5_CDK5_ST	Q9UM11	FZR1	Q00535	CDK5	S70	P71A	71	Missense	proximal	1	no	17.115	6.088	EPSD	COSMIC	8.808	Loss
CMGC_CDK_CDK5_CDK5_ST	Q9UM11	FZR1	Q00535	CDK5	S72	S70F	70	Missense	proximal	-2	no	10.337	9.778	EPSD	COSMIC;GDSC;CCLE	8.808	Down-regulation
CMGC_CDK_CDK5_CDK5_ST	Q9UM11	FZR1	Q00535	CDK5	S72	P71A	71	Missense	proximal	-1	no	10.337	10.332	EPSD	COSMIC	8.808	Down-regulation
CMGC_CDK_CDK5_CDK5_ST	Q9UM11	FZR1	Q00535	CDK5	T121	K124N	124	Missense	distal	3	no	19.277	17.344	EPSD;PhosphoSitePlus	COSMIC	8.808	Down-regulation
CMGC_CDK_CDK5_CDK5_ST	Q9UM11	FZR1	Q00535	CDK5	S146	P152L	152	Missense	distal	6	no	16.724	16.710	EPSD	COSMIC;GDSC;CCLE	8.808	Down-regulation
CMGC_CDK_CDK5_CDK5_ST	Q9UM11	FZR1	Q00535	CDK5	S146	P147S	147	Missense	proximal	1	no	16.724	4.823	EPSD	COSMIC	8.808	Loss
CMGC_CDK_CDK5_CDK5_ST	Q9UM11	FZR1	Q00535	CDK5	S151	N155S	155	Missense	distal	4	no	17.843	17.873	EPSD	COSMIC;GDSC;CCLE	8.808	Up-regulation
CMGC_CDK_CDK5_CDK5_ST	Q9UM11	FZR1	Q00535	CDK5	S151	P152L	152	Missense	proximal	1	no	17.843	5.893	EPSD	COSMIC;GDSC;CCLE	8.808	Loss
CMGC_CDK_CDK5_CDK5_ST	Q9UM11	FZR1	Q00535	CDK5	S151	P147S	147	Missense	distal	-4	no	17.843	18.189	EPSD	COSMIC	8.808	Up-regulation
CMGC_CDK_CDK5_CDK5_ST	Q9UM11	FZR1	Q00535	CDK5	T300	T300P	300	Missense	central	0	yes	16.244	0.000	EPSD	COSMIC	8.808	Loss
CMGC_CDK_CDK5_CDK5_ST	Q9UM11	FZR1	Q00535	CDK5	S346	S343A	343	Missense	distal	-3	no	17.764	17.717	EPSD	COSMIC	8.808	Down-regulation
CMGC_CDK_CDK5_CDK5_ST	Q9UM11	FZR1	Q00535	CDK5	S346	E353D	353	Missense	distal	7	no	17.764	17.765	EPSD	COSMIC	8.808	Up-regulation
CMGC_CDK_CDK5_CDK5_ST	Q9UM11	FZR1	Q00535	CDK5	S346	V348M	348	Missense	proximal	2	no	17.764	17.604	EPSD	COSMIC	8.808	Down-regulation
CMGC_CDK_CDK5_CDK5_ST	Q9UM11	FZR1	Q00535	CDK5	S346	Q350L	350	Missense	distal	4	no	17.764	17.711	EPSD	COSMIC	8.808	Down-regulation
CMGC_CDK_CDK5_CDK5_ST	Q9UM11	FZR1	Q00535	CDK5	S346	H342D	342	Missense	distal	-4	no	17.764	17.769	EPSD	COSMIC	8.808	Up-regulation
CMGC_CDK_CDK5_CDK5_ST	Q9UM11	FZR1	Q00535	CDK5	T493	S487T	487	Missense	distal	-6	no	9.933	9.905	EPSD	COSMIC	8.808	Down-regulation
CMGC_CDK_CDK5_CDK5_ST	Q9UM11	FZR1	Q00535	CDK5	T493	R494M	494	Missense	proximal	1	no	9.933	-1.383	EPSD	COSMIC	8.808	Loss
CMGC_CDK_CDK5_CDK5_ST	Q9UM11	FZR1	Q00535	CDK5	T493	S487F	487	Missense	distal	-6	no	9.933	9.760	EPSD	COSMIC;GDSC;CCLE	8.808	Down-regulation
CMGC_CDK_CDK5_CDK5_ST	P12931	SRC	Q00535	CDK5	S12	K9T	9	Missense	distal	-3	no	12.092	12.056	EPSD	COSMIC	8.808	Down-regulation
CMGC_CDK_CDK5_CDK5_ST	P12931	SRC	Q00535	CDK5	S12	R16H	16	Missense	distal	4	no	12.092	12.052	EPSD	COSMIC	8.808	Down-regulation
CMGC_CDK_CDK5_CDK5_ST	P12931	SRC	Q00535	CDK5	S12	R15C	15	Missense	distal	3	no	12.092	9.796	EPSD	COSMIC	8.808	Down-regulation
CMGC_CDK_CDK5_CDK5_ST	P12931	SRC	Q00535	CDK5	T37	P33L	33	Missense	distal	-4	no	18.064	17.591	EPSD	COSMIC	8.808	Down-regulation
CMGC_CDK_CDK5_CDK5_ST	P12931	SRC	Q00535	CDK5	T37	A34T	34	Missense	distal	-3	no	18.064	18.109	EPSD	COSMIC	8.808	Up-regulation
CMGC_CDK_CDK5_CDK5_ST	P12931	SRC	Q00535	CDK5	T37	A44V	44	Missense	distal	7	no	18.064	18.071	EPSD	COSMIC	8.808	Up-regulation
CMGC_CDK_CDK5_CDK5_ST	P12931	SRC	Q00535	CDK5	S75	S70L	70	Missense	distal	-5	no	19.464	19.244	PhosphoSitePlus	COSMIC	8.808	Down-regulation
CMGC_CDK_CDK5_CDK5_ST	P12931	SRC	Q00535	CDK5	S75	S75F	75	Missense	central	0	yes	19.464	0.000	PhosphoSitePlus	COSMIC	8.808	Loss
CMGC_CDK_CDK5_CDK5_ST	P12931	SRC	Q00535	CDK5	S75	S69A	69	Missense	distal	-6	no	19.464	19.349	PhosphoSitePlus	COSMIC	8.808	Down-regulation
CMGC_CDK_CDK5_CDK5_ST	P12931	SRC	Q00535	CDK5	S306	A309V	309	Missense	distal	3	no	18.794	19.046	EPSD	COSMIC	8.808	Up-regulation
CMGC_CDK_CDK5_CDK5_ST	P12931	SRC	Q00535	CDK5	S306	P307S	307	Missense	proximal	1	no	18.794	6.893	EPSD	COSMIC	8.808	Loss
CMGC_CDK_CDK5_CDK5_ST	P12931	SRC	Q00535	CDK5	S306	T299A	299	Missense	distal	-7	no	18.794	18.754	EPSD	COSMIC	8.808	Down-regulation
CMGC_CDK_CDK5_CDK5_ST	P15927	RPA2	Q00535	CDK5	S13	Y14N	14	Missense	proximal	1	no	-1.282	9.455	EPSD	COSMIC	8.808	Gain
CMGC_CDK_CDK5_CDK5_ST	P15927	RPA2	Q00535	CDK5	T21	Y14N	14	Missense	distal	-7	no	8.809	8.849	EPSD	COSMIC	8.808	Up-regulation
CMGC_CDK_CDK5_CDK5_ST	P15927	RPA2	Q00535	CDK5	S29	Q34K	34	Missense	distal	5	no	17.467	17.667	PhosphoSitePlus;EPSD	COSMIC	8.808	Up-regulation
CMGC_CDK_CDK5_CDK5_ST	P15927	RPA2	Q00535	CDK5	S33	Q34K	34	Missense	proximal	1	no	9.522	0.320	EPSD;PhosphoSitePlus	COSMIC	8.808	Loss
CMGC_CDK_CDK5_CDK5_ST	P15927	RPA2	Q00535	CDK5	S33	K37N	37	Missense	distal	4	no	9.522	9.428	EPSD;PhosphoSitePlus	COSMIC	8.808	Down-regulation
CMGC_CDK_CDK5_CDK5_ST	P15927	RPA2	Q00535	CDK5	S39	Q34K	34	Missense	distal	-5	no	10.639	10.835	EPSD	COSMIC	8.808	Up-regulation
CMGC_CDK_CDK5_CDK5_ST	P15927	RPA2	Q00535	CDK5	S39	K37N	37	Missense	proximal	-2	no	10.639	10.456	EPSD	COSMIC	8.808	Down-regulation
CMGC_CDK_CDK5_CDK5_ST	P15927	RPA2	Q00535	CDK5	S72	Q73H	73	Missense	proximal	1	no	9.145	-0.391	EPSD	COSMIC	8.808	Loss
CMGC_CDK_CDK5_CDK5_ST	P15927	RPA2	Q00535	CDK5	S174	P176S	176	Missense	proximal	2	no	9.824	9.806	EPSD	COSMIC	8.808	Down-regulation
CMGC_CDK_CDK5_CDK5_ST	O14939	PLD2	Q00535	CDK5	S77	G78R	78	Missense	proximal	1	no	-2.353	10.116	EPSD	COSMIC	8.808	Gain
CMGC_CDK_CDK5_CDK5_ST	O14939	PLD2	Q00535	CDK5	S134	G140D	140	Missense	distal	6	no	18.193	18.192	PhosphoSitePlus	COSMIC;GDSC;CCLE	8.808	Down-regulation
CMGC_CDK_CDK5_CDK5_ST	O14939	PLD2	Q00535	CDK5	S134	R137Q	137	Missense	distal	3	no	18.193	16.390	PhosphoSitePlus	COSMIC	8.808	Down-regulation
CMGC_CDK_CDK5_CDK5_ST	O14939	PLD2	Q00535	CDK5	S484	P487A	487	Missense	distal	3	no	10.070	9.825	EPSD	COSMIC	8.808	Down-regulation
CMGC_CDK_CDK5_CDK5_ST	O14939	PLD2	Q00535	CDK5	S484	R490H	490	Missense	distal	6	no	10.070	10.059	EPSD	COSMIC;CCLE	8.808	Down-regulation
CMGC_CDK_CDK5_CDK5_ST	O14939	PLD2	Q00535	CDK5	T488	P487A	487	Missense	proximal	-1	no	18.659	18.654	EPSD	COSMIC	8.808	Down-regulation
CMGC_CDK_CDK5_CDK5_ST	O14939	PLD2	Q00535	CDK5	T488	R490H	490	Missense	proximal	2	no	18.659	18.544	EPSD	COSMIC;CCLE	8.808	Down-regulation
CMGC_CDK_CDK5_CDK5_ST	O14939	PLD2	Q00535	CDK5	S493	P487A	487	Missense	distal	-6	no	19.277	19.202	EPSD	COSMIC	8.808	Down-regulation
CMGC_CDK_CDK5_CDK5_ST	O14939	PLD2	Q00535	CDK5	S493	R490H	490	Missense	distal	-3	no	19.277	19.245	EPSD	COSMIC;CCLE	8.808	Down-regulation
CMGC_CDK_CDK5_CDK5_ST	O14939	PLD2	Q00535	CDK5	T496	R490H	490	Missense	distal	-6	no	16.454	16.388	EPSD	COSMIC;CCLE	8.808	Down-regulation
CMGC_CDK_CDK5_CDK5_ST	O14939	PLD2	Q00535	CDK5	T496	N502Y	502	Missense	distal	6	no	16.454	16.444	EPSD	COSMIC	8.808	Down-regulation
CMGC_CDK_CDK5_CDK5_ST	O14939	PLD2	Q00535	CDK5	T575	T569A	569	Missense	distal	-6	no	16.231	16.145	EPSD	COSMIC	8.808	Down-regulation
CMGC_CDK_CDK5_CDK5_ST	O14939	PLD2	Q00535	CDK5	T575	K574M	574	Missense	proximal	-1	no	16.231	16.222	EPSD	COSMIC	8.808	Down-regulation
CMGC_CDK_CDK5_CDK5_ST	O14939	PLD2	Q00535	CDK5	S888	P890L	890	Missense	proximal	2	no	17.217	17.051	EPSD	COSMIC;GDSC;CCLE	8.808	Down-regulation
CMGC_CDK_CDK5_CDK5_ST	O14939	PLD2	Q00535	CDK5	S888	P889F	889	Missense	proximal	1	no	17.217	-4.763	EPSD	COSMIC	8.808	Loss
CMGC_CDK_CDK5_CDK5_ST	Q05397	PTK2	Q00535	CDK5	T13	H12D	12	Missense	proximal	-1	no	18.075	18.073	EPSD	COSMIC	8.808	Down-regulation
CMGC_CDK_CDK5_CDK5_ST	Q05397	PTK2	Q00535	CDK5	S17	L22F	22	Missense	distal	5	no	9.267	9.213	EPSD	COSMIC	8.808	Down-regulation
CMGC_CDK_CDK5_CDK5_ST	Q05397	PTK2	Q00535	CDK5	S17	T24S	24	Missense	distal	7	no	9.267	9.268	EPSD	COSMIC	8.808	Up-regulation
CMGC_CDK_CDK5_CDK5_ST	Q05397	PTK2	Q00535	CDK5	S17	H12D	12	Missense	distal	-5	no	9.267	9.194	EPSD	COSMIC	8.808	Down-regulation
CMGC_CDK_CDK5_CDK5_ST	Q05397	PTK2	Q00535	CDK5	S29	L22F	22	Missense	distal	-7	no	17.967	17.939	EPSD	COSMIC	8.808	Down-regulation
CMGC_CDK_CDK5_CDK5_ST	Q05397	PTK2	Q00535	CDK5	S29	T24S	24	Missense	distal	-5	no	17.967	17.993	EPSD	COSMIC	8.808	Up-regulation
CMGC_CDK_CDK5_CDK5_ST	Q05397	PTK2	Q00535	CDK5	S29	R28H	28	Missense	proximal	-1	no	17.967	17.965	EPSD	COSMIC	8.808	Down-regulation
CMGC_CDK_CDK5_CDK5_ST	Q05397	PTK2	Q00535	CDK5	S248	E245K	245	Missense	distal	-3	no	15.944	16.017	EPSD	COSMIC	8.808	Up-regulation
CMGC_CDK_CDK5_CDK5_ST	Q05397	PTK2	Q00535	CDK5	S248	L241P	241	Missense	distal	-7	no	15.944	15.996	EPSD	COSMIC	8.808	Up-regulation
CMGC_CDK_CDK5_CDK5_ST	Q05397	PTK2	Q00535	CDK5	S248	R252K	252	Missense	distal	4	no	15.944	15.992	EPSD	COSMIC	8.808	Up-regulation
CMGC_CDK_CDK5_CDK5_ST	Q05397	PTK2	Q00535	CDK5	S248	V250L	250	Missense	proximal	2	no	15.944	15.810	EPSD	COSMIC	8.808	Down-regulation
CMGC_CDK_CDK5_CDK5_ST	Q05397	PTK2	Q00535	CDK5	S248	K255N	255	Missense	distal	7	no	15.944	15.933	EPSD	COSMIC	8.808	Down-regulation
CMGC_CDK_CDK5_CDK5_ST	Q05397	PTK2	Q00535	CDK5	S443	P447S	447	Missense	distal	4	no	16.344	16.346	EPSD	COSMIC	8.808	Up-regulation
CMGC_CDK_CDK5_CDK5_ST	Q05397	PTK2	Q00535	CDK5	S443	S443R	443	Missense	central	0	yes	16.344	0.000	EPSD	COSMIC	8.808	Loss
CMGC_CDK_CDK5_CDK5_ST	Q05397	PTK2	Q00535	CDK5	S443	Y441F	441	Missense	proximal	-2	no	16.344	16.214	EPSD	COSMIC	8.808	Down-regulation
CMGC_CDK_CDK5_CDK5_ST	Q05397	PTK2	Q00535	CDK5	S705	G706R	706	Missense	proximal	1	no	-3.556	8.913	EPSD	COSMIC	8.808	Gain
CMGC_CDK_CDK5_CDK5_ST	Q05397	PTK2	Q00535	CDK5	S716	P712L	712	Missense	distal	-4	no	8.899	8.426	EPSD	COSMIC	8.808	Loss
CMGC_CDK_CDK5_CDK5_ST	Q05397	PTK2	Q00535	CDK5	S716	S722I	722	Missense	distal	6	no	8.899	8.892	EPSD	COSMIC	8.808	Down-regulation
CMGC_CDK_CDK5_CDK5_ST	Q05397	PTK2	Q00535	CDK5	S722	S722I	722	Missense	central	0	yes	17.684	0.000	EPSD	COSMIC	8.808	Loss
CMGC_CDK_CDK5_CDK5_ST	Q05397	PTK2	Q00535	CDK5	S732	G728E	728	Missense	distal	-4	no	17.875	18.089	EPSD	COSMIC	8.808	Up-regulation
CMGC_CDK_CDK5_CDK5_ST	Q05397	PTK2	Q00535	CDK5	S840	R841L	841	Missense	proximal	1	no	8.909	5.906	EPSD	COSMIC	8.808	Loss
CMGC_CDK_CDK5_CDK5_ST	Q05397	PTK2	Q00535	CDK5	S893	A889V	889	Missense	distal	-4	no	16.233	16.653	EPSD	COSMIC	8.808	Up-regulation
CMGC_CDK_CDK5_CDK5_ST	Q05397	PTK2	Q00535	CDK5	S893	E900V	900	Missense	distal	7	no	16.233	16.240	EPSD	COSMIC	8.808	Up-regulation
CMGC_CDK_CDK5_CDK5_ST	Q05397	PTK2	Q00535	CDK5	S910	P906H	906	Missense	distal	-4	no	17.957	17.622	PhosphoSitePlus	COSMIC	8.808	Down-regulation
CMGC_CDK_CDK5_CDK5_ST	Q05397	PTK2	Q00535	CDK5	S910	P911S	911	Missense	proximal	1	no	17.957	6.055	PhosphoSitePlus	COSMIC	8.808	Loss
CMGC_CDK_CDK5_CDK5_ST	Q05397	PTK2	Q00535	CDK5	S920	D918G	918	Missense	proximal	-2	no	9.926	9.795	EPSD	COSMIC	8.808	Down-regulation
CMGC_CDK_CDK5_CDK5_ST	Q05397	PTK2	Q00535	CDK5	S920	E926K	926	Missense	distal	6	no	9.926	9.944	EPSD	COSMIC	8.808	Up-regulation
CMGC_CDK_CDK5_CDK5_ST	Q05397	PTK2	Q00535	CDK5	S920	Y925C	925	Missense	distal	5	no	9.926	9.910	EPSD	COSMIC	8.808	Down-regulation
CMGC_CDK_CDK5_CDK5_ST	Q05397	PTK2	Q00535	CDK5	S920	R919L	919	Missense	proximal	-1	no	9.926	9.920	EPSD	COSMIC	8.808	Down-regulation
CMGC_CDK_CDK5_CDK5_ST	Q05397	PTK2	Q00535	CDK5	S920	R919Q	919	Missense	proximal	-1	no	9.926	9.924	EPSD	COSMIC	8.808	Down-regulation
CMGC_CDK_CDK5_CDK5_ST	P10275	AR	Q00535	CDK5	S83	Q79E	79	Missense	distal	-4	no	17.367	17.210	EPSD;PhosphoSitePlus	COSMIC	8.808	Down-regulation
CMGC_CDK_CDK5_CDK5_ST	P10275	AR	Q00535	CDK5	S83	Q86K	86	Missense	distal	3	no	17.367	19.489	EPSD;PhosphoSitePlus	COSMIC	8.808	Up-regulation
CMGC_CDK_CDK5_CDK5_ST	P10275	AR	Q00535	CDK5	S83	E81Q	81	Missense	proximal	-2	no	17.367	17.616	EPSD;PhosphoSitePlus	COSMIC	8.808	Up-regulation
CMGC_CDK_CDK5_CDK5_ST	P10275	AR	Q00535	CDK5	S83	Q90H	90	Missense	distal	7	no	17.367	17.366	EPSD;PhosphoSitePlus	COSMIC	8.808	Down-regulation
CMGC_CDK_CDK5_CDK5_ST	P10275	AR	Q00535	CDK5	S83	Q79R	79	Missense	distal	-4	no	17.367	17.377	EPSD;PhosphoSitePlus	COSMIC	8.808	Up-regulation
CMGC_CDK_CDK5_CDK5_ST	P10275	AR	Q00535	CDK5	S83	P84H	84	Missense	proximal	1	no	17.367	-1.146	EPSD;PhosphoSitePlus	COSMIC	8.808	Loss
CMGC_CDK_CDK5_CDK5_ST	P10275	AR	Q00535	CDK5	S96	S96Y	96	Missense	central	0	yes	17.005	0.000	EPSD	COSMIC	8.808	Loss
CMGC_CDK_CDK5_CDK5_ST	P10275	AR	Q00535	CDK5	S96	Q90H	90	Missense	distal	-6	no	17.005	16.998	EPSD	COSMIC	8.808	Down-regulation
CMGC_CDK_CDK5_CDK5_ST	P10275	AR	Q00535	CDK5	S96	S96F	96	Missense	central	0	yes	17.005	0.000	EPSD	COSMIC	8.808	Loss
CMGC_CDK_CDK5_CDK5_ST	P10275	AR	Q00535	CDK5	S258	L257P	257	Missense	proximal	-1	no	15.761	15.766	EPSD	COSMIC	8.808	Up-regulation
CMGC_CDK_CDK5_CDK5_ST	P10275	AR	Q00535	CDK5	S258	R264Q	264	Missense	distal	6	no	15.761	15.750	EPSD	COSMIC	8.808	Down-regulation
CMGC_CDK_CDK5_CDK5_ST	P10275	AR	Q00535	CDK5	S258	E252G	252	Missense	distal	-6	no	15.761	15.754	EPSD	COSMIC	8.808	Down-regulation
CMGC_CDK_CDK5_CDK5_ST	P10275	AR	Q00535	CDK5	S258	E252K	252	Missense	distal	-6	no	15.761	15.891	EPSD	COSMIC	8.808	Up-regulation
CMGC_CDK_CDK5_CDK5_ST	P10275	AR	Q00535	CDK5	S258	E255K	255	Missense	distal	-3	no	15.761	15.834	EPSD	COSMIC	8.808	Up-regulation
CMGC_CDK_CDK5_CDK5_ST	P10275	AR	Q00535	CDK5	T282	R280H	280	Missense	proximal	-2	no	17.057	16.796	EPSD	COSMIC	8.808	Down-regulation
CMGC_CDK_CDK5_CDK5_ST	P10275	AR	Q00535	CDK5	T282	P276S	276	Missense	distal	-6	no	17.057	17.097	EPSD	COSMIC	8.808	Up-regulation
CMGC_CDK_CDK5_CDK5_ST	P10275	AR	Q00535	CDK5	T282	P283S	283	Missense	proximal	1	no	17.057	5.156	EPSD	COSMIC	8.808	Loss
CMGC_CDK_CDK5_CDK5_ST	P10275	AR	Q00535	CDK5	T282	A278T	278	Missense	distal	-4	no	17.057	17.457	EPSD	COSMIC	8.808	Up-regulation
CMGC_CDK_CDK5_CDK5_ST	P10275	AR	Q00535	CDK5	T282	A285D	285	Missense	distal	3	no	17.057	16.668	EPSD	COSMIC	8.808	Down-regulation
CMGC_CDK_CDK5_CDK5_ST	P10275	AR	Q00535	CDK5	T282	A278V	278	Missense	distal	-4	no	17.057	17.477	EPSD	COSMIC	8.808	Up-regulation
CMGC_CDK_CDK5_CDK5_ST	P10275	AR	Q00535	CDK5	T282	A285V	285	Missense	distal	3	no	17.057	17.309	EPSD	COSMIC	8.808	Up-regulation
CMGC_CDK_CDK5_CDK5_ST	P10275	AR	Q00535	CDK5	S298	G292S	292	Missense	distal	-6	no	8.738	8.833	EPSD	COSMIC	8.808	Gain
CMGC_CDK_CDK5_CDK5_ST	P10275	AR	Q00535	CDK5	S310	D305N	305	Missense	distal	-5	no	19.095	19.169	PhosphoSitePlus;EPSD	COSMIC	8.808	Up-regulation
CMGC_CDK_CDK5_CDK5_ST	P10275	AR	Q00535	CDK5	S310	S310F	310	Missense	central	0	yes	19.095	0.000	PhosphoSitePlus;EPSD	COSMIC	8.808	Loss
CMGC_CDK_CDK5_CDK5_ST	P10275	AR	Q00535	CDK5	S310	E304K	304	Missense	distal	-6	no	19.095	19.225	PhosphoSitePlus;EPSD	COSMIC	8.808	Up-regulation
CMGC_CDK_CDK5_CDK5_ST	P10275	AR	Q00535	CDK5	S310	T306I	306	Missense	distal	-4	no	19.095	18.982	PhosphoSitePlus;EPSD	COSMIC;GDSC;CCLE	8.808	Down-regulation
CMGC_CDK_CDK5_CDK5_ST	P10275	AR	Q00535	CDK5	S310	F312L	312	Missense	proximal	2	no	19.095	19.157	PhosphoSitePlus;EPSD	COSMIC	8.808	Up-regulation
CMGC_CDK_CDK5_CDK5_ST	P10275	AR	Q00535	CDK5	S426	A430T	430	Missense	distal	4	no	18.457	18.517	EPSD	COSMIC	8.808	Up-regulation
CMGC_CDK_CDK5_CDK5_ST	P10275	AR	Q00535	CDK5	S426	A420E	420	Missense	distal	-6	no	18.457	18.484	EPSD	COSMIC	8.808	Up-regulation
CMGC_CDK_CDK5_CDK5_ST	P10275	AR	Q00535	CDK5	S426	G421V	421	Missense	distal	-5	no	18.457	18.572	EPSD	COSMIC	8.808	Up-regulation
CMGC_CDK_CDK5_CDK5_ST	P10275	AR	Q00535	CDK5	S426	A430S	430	Missense	distal	4	no	18.457	18.519	EPSD	COSMIC	8.808	Up-regulation
CMGC_CDK_CDK5_CDK5_ST	P10275	AR	Q00535	CDK5	S426	G421R	421	Missense	distal	-5	no	18.457	18.709	EPSD	COSMIC	8.808	Up-regulation
CMGC_CDK_CDK5_CDK5_ST	P10275	AR	Q00535	CDK5	S426	S433L	433	Missense	distal	7	no	18.457	18.445	EPSD	COSMIC	8.808	Down-regulation
CMGC_CDK_CDK5_CDK5_ST	P10275	AR	Q00535	CDK5	S426	S424C	424	Missense	proximal	-2	no	18.457	17.984	EPSD	COSMIC	8.808	Down-regulation
CMGC_CDK_CDK5_CDK5_ST	P10275	AR	Q00535	CDK5	S426	S424F	424	Missense	proximal	-2	no	18.457	17.898	EPSD	COSMIC	8.808	Down-regulation
CMGC_CDK_CDK5_CDK5_ST	P10275	AR	Q00535	CDK5	S516	P515H	515	Missense	proximal	-1	no	17.169	17.167	EPSD	COSMIC	8.808	Down-regulation
CMGC_CDK_CDK5_CDK5_ST	P10275	AR	Q00535	CDK5	S516	E523K	523	Missense	distal	7	no	17.169	17.185	EPSD	COSMIC	8.808	Up-regulation
CMGC_CDK_CDK5_CDK5_ST	P10275	AR	Q00535	CDK5	S516	P515S	515	Missense	proximal	-1	no	17.169	17.170	EPSD	COSMIC	8.808	Up-regulation
CMGC_CDK_CDK5_CDK5_ST	P10275	AR	Q00535	CDK5	S647	S648R	648	Missense	proximal	1	no	6.435	9.389	EPSD	COSMIC	8.808	Gain
CMGC_CDK_CDK5_CDK5_ST	P10275	AR	Q00535	CDK5	S647	S648N	648	Missense	proximal	1	no	6.435	9.097	EPSD	COSMIC	8.808	Gain
CMGC_CDK_CDK5_CDK5_ST	P10275	AR	Q00535	CDK5	S651	A646D	646	Missense	distal	-5	no	17.918	17.934	EPSD	COSMIC	8.808	Up-regulation
CMGC_CDK_CDK5_CDK5_ST	P10275	AR	Q00535	CDK5	S651	S648R	648	Missense	distal	-3	no	17.918	17.933	EPSD	COSMIC	8.808	Up-regulation
CMGC_CDK_CDK5_CDK5_ST	P10275	AR	Q00535	CDK5	S651	S648N	648	Missense	distal	-3	no	17.918	17.901	EPSD	COSMIC	8.808	Down-regulation
CMGC_CDK_CDK5_CDK5_ST	P10275	AR	Q00535	CDK5	S651	E654K	654	Missense	distal	3	no	17.918	20.204	EPSD	COSMIC	8.808	Up-regulation
CMGC_CDK_CDK5_CDK5_ST	P10275	AR	Q00535	CDK5	S651	S647F	647	Missense	distal	-4	no	17.918	16.757	EPSD	COSMIC	8.808	Down-regulation
CMGC_CDK_CDK5_CDK5_ST	P10275	AR	Q00535	CDK5	S651	E655D	655	Missense	distal	4	no	17.918	17.910	EPSD	COSMIC	8.808	Down-regulation
CMGC_CDK_CDK5_CDK5_ST	P10275	AR	Q00535	CDK5	T656	E654K	654	Missense	proximal	-2	no	8.539	8.952	EPSD	COSMIC	8.808	Gain
CMGC_CDK_CDK5_CDK5_ST	O94811	TPPP	Q00535	CDK5	S45	S49G	49	Missense	distal	4	no	15.499	15.448	EPSD	COSMIC	8.808	Down-regulation
CMGC_CDK_CDK5_CDK5_ST	O94811	TPPP	Q00535	CDK5	S160	R165M	165	Missense	distal	5	no	18.510	18.243	PhosphoSitePlus;EPSD	COSMIC	8.808	Down-regulation
CMGC_CDK_CDK5_CDK5_ST	O94811	TPPP	Q00535	CDK5	S164	R165M	165	Missense	proximal	1	no	9.997	-1.319	EPSD	COSMIC	8.808	Loss
CMGC_CDK_CDK5_CDK5_ST	O94811	TPPP	Q00535	CDK5	S164	D168N	168	Missense	distal	4	no	9.997	10.027	EPSD	COSMIC	8.808	Up-regulation
CMGC_CDK_CDK5_CDK5_ST	P37231	PPARG	Q00535	CDK5	S112	V108A	108	Missense	distal	-4	no	17.396	16.977	EPSD	COSMIC	8.808	Down-regulation
CMGC_CDK_CDK5_CDK5_ST	P37231	PPARG	Q00535	CDK5	S273	D271E	271	Missense	proximal	-2	no	17.838	17.730	PhosphoSitePlus	COSMIC	8.808	Down-regulation
CMGC_CDK_CDK5_CDK5_ST	Q9Y210	TRPC6	Q00535	CDK5	S4	S2R	2	Missense	proximal	-2	no	16.867	16.911	EPSD	COSMIC	8.808	Up-regulation
CMGC_CDK_CDK5_CDK5_ST	Q9Y210	TRPC6	Q00535	CDK5	S4	G8V	8	Missense	distal	4	no	16.867	16.898	EPSD	COSMIC	8.808	Up-regulation
CMGC_CDK_CDK5_CDK5_ST	Q9Y210	TRPC6	Q00535	CDK5	S13	A19G	19	Missense	distal	6	no	9.389	9.391	EPSD	COSMIC;CCLE	8.808	Up-regulation
CMGC_CDK_CDK5_CDK5_ST	Q9Y210	TRPC6	Q00535	CDK5	S13	G8V	8	Missense	distal	-5	no	9.389	9.504	EPSD	COSMIC	8.808	Up-regulation
CMGC_CDK_CDK5_CDK5_ST	Q9Y210	TRPC6	Q00535	CDK5	S14	A19G	19	Missense	distal	5	no	19.579	19.610	PhosphoSitePlus	COSMIC;CCLE	8.808	Up-regulation
CMGC_CDK_CDK5_CDK5_ST	Q9Y210	TRPC6	Q00535	CDK5	S14	G8V	8	Missense	distal	-6	no	19.579	19.629	PhosphoSitePlus	COSMIC	8.808	Up-regulation
CMGC_CDK_CDK5_CDK5_ST	Q9Y210	TRPC6	Q00535	CDK5	S195	T194A	194	Missense	proximal	-1	no	17.799	17.794	EPSD	COSMIC	8.808	Down-regulation
CMGC_CDK_CDK5_CDK5_ST	Q9Y210	TRPC6	Q00535	CDK5	S270	R273K	273	Missense	distal	3	no	11.090	11.409	EPSD	COSMIC	8.808	Up-regulation
CMGC_CDK_CDK5_CDK5_ST	Q9Y210	TRPC6	Q00535	CDK5	S270	I274S	274	Missense	distal	4	no	11.090	11.133	EPSD	COSMIC	8.808	Up-regulation
CMGC_CDK_CDK5_CDK5_ST	Q9Y210	TRPC6	Q00535	CDK5	S272	R273K	273	Missense	proximal	1	no	9.508	0.277	EPSD	COSMIC	8.808	Loss
CMGC_CDK_CDK5_CDK5_ST	Q9Y210	TRPC6	Q00535	CDK5	S272	G279D	279	Missense	distal	7	no	9.508	9.509	EPSD	COSMIC	8.808	Up-regulation
CMGC_CDK_CDK5_CDK5_ST	Q9Y210	TRPC6	Q00535	CDK5	S272	G279S	279	Missense	distal	7	no	9.508	9.517	EPSD	COSMIC	8.808	Up-regulation
CMGC_CDK_CDK5_CDK5_ST	Q9Y210	TRPC6	Q00535	CDK5	S272	I274S	274	Missense	proximal	2	no	9.508	9.578	EPSD	COSMIC	8.808	Up-regulation
CMGC_CDK_CDK5_CDK5_ST	Q9Y210	TRPC6	Q00535	CDK5	S282	G279S	279	Missense	distal	-3	no	17.661	17.701	EPSD	COSMIC	8.808	Up-regulation
CMGC_CDK_CDK5_CDK5_ST	Q9Y210	TRPC6	Q00535	CDK5	S282	A281S	281	Missense	proximal	-1	no	17.661	17.666	EPSD	COSMIC	8.808	Up-regulation
CMGC_CDK_CDK5_CDK5_ST	Q9NXR1	NDE1	Q00535	CDK5	S165	R168K	168	Missense	distal	3	no	8.687	9.006	EPSD	COSMIC	8.808	Gain
CMGC_CDK_CDK5_CDK5_ST	Q9NXR1	NDE1	Q00535	CDK5	S165	Q167K	167	Missense	proximal	2	no	8.687	8.875	EPSD	COSMIC	8.808	Gain
CMGC_CDK_CDK5_CDK5_ST	Q9NXR1	NDE1	Q00535	CDK5	T191	M193I	193	Missense	proximal	2	no	16.727	16.830	PhosphoSitePlus	COSMIC	8.808	Up-regulation
CMGC_CDK_CDK5_CDK5_ST	Q9NXR1	NDE1	Q00535	CDK5	T191	P189H	189	Missense	proximal	-2	no	16.727	16.411	PhosphoSitePlus	COSMIC	8.808	Down-regulation
CMGC_CDK_CDK5_CDK5_ST	Q9NXR1	NDE1	Q00535	CDK5	T215	T215M	215	Missense	central	0	yes	17.185	0.000	EPSD	COSMIC	8.808	Loss
CMGC_CDK_CDK5_CDK5_ST	Q9NXR1	NDE1	Q00535	CDK5	T215	S214F	214	Missense	proximal	-1	no	17.185	17.177	EPSD	COSMIC	8.808	Down-regulation
CMGC_CDK_CDK5_CDK5_ST	Q9NXR1	NDE1	Q00535	CDK5	S224	S225N	225	Missense	proximal	1	no	6.384	9.047	EPSD	COSMIC	8.808	Gain
CMGC_CDK_CDK5_CDK5_ST	Q9NXR1	NDE1	Q00535	CDK5	T228	S225N	225	Missense	distal	-3	no	17.529	17.512	EPSD	COSMIC	8.808	Down-regulation
CMGC_CDK_CDK5_CDK5_ST	Q9NXR1	NDE1	Q00535	CDK5	T228	S223N	223	Missense	distal	-5	no	17.529	17.438	EPSD	COSMIC	8.808	Down-regulation
CMGC_CDK_CDK5_CDK5_ST	Q9NXR1	NDE1	Q00535	CDK5	T243	P244S	244	Missense	proximal	1	no	17.944	6.043	EPSD	COSMIC	8.808	Loss
CMGC_CDK_CDK5_CDK5_ST	Q9NXR1	NDE1	Q00535	CDK5	T246	P244S	244	Missense	proximal	-2	no	16.791	16.692	EPSD	COSMIC	8.808	Down-regulation
CMGC_CDK_CDK5_CDK5_ST	Q9NXR1	NDE1	Q00535	CDK5	S282	R275Q	275	Missense	distal	-7	no	19.191	19.171	EPSD	COSMIC	8.808	Down-regulation
CMGC_CDK_CDK5_CDK5_ST	Q9NXR1	NDE1	Q00535	CDK5	S333	S331P	331	Missense	proximal	-2	no	17.849	17.947	EPSD	COSMIC	8.808	Up-regulation
CMGC_CDK_CDK5_CDK5_ST	P04637	TP53	Q00535	CDK5	S15	E11Q	11	Missense	distal	-4	no	11.612	11.768	EPSD;PhosphoSitePlus	COSMIC;GDSC;CCLE	8.808	Up-regulation
CMGC_CDK_CDK5_CDK5_ST	P04637	TP53	Q00535	CDK5	S15	S20L	20	Missense	distal	5	no	11.612	11.427	EPSD;PhosphoSitePlus	COSMIC	8.808	Down-regulation
CMGC_CDK_CDK5_CDK5_ST	P04637	TP53	Q00535	CDK5	S15	Q16L	16	Missense	proximal	1	no	11.612	8.638	EPSD;PhosphoSitePlus	COSMIC;GDSC;CCLE	8.808	Loss
CMGC_CDK_CDK5_CDK5_ST	P04637	TP53	Q00535	CDK5	S15	P13S	13	Missense	proximal	-2	no	11.612	11.513	EPSD;PhosphoSitePlus	COSMIC	8.808	Down-regulation
CMGC_CDK_CDK5_CDK5_ST	P04637	TP53	Q00535	CDK5	S15	E17K	17	Missense	proximal	2	no	11.612	11.862	EPSD;PhosphoSitePlus	COSMIC	8.808	Up-regulation
CMGC_CDK_CDK5_CDK5_ST	P04637	TP53	Q00535	CDK5	S15	V10I	10	Missense	distal	-5	no	11.612	11.536	EPSD;PhosphoSitePlus	COSMIC	8.808	Down-regulation
CMGC_CDK_CDK5_CDK5_ST	P04637	TP53	Q00535	CDK5	S15	P8L	8	Missense	distal	-7	no	11.612	11.560	EPSD;PhosphoSitePlus	COSMIC	8.808	Down-regulation
CMGC_CDK_CDK5_CDK5_ST	P04637	TP53	Q00535	CDK5	S15	P8S	8	Missense	distal	-7	no	11.612	11.616	EPSD;PhosphoSitePlus	COSMIC	8.808	Up-regulation
CMGC_CDK_CDK5_CDK5_ST	P04637	TP53	Q00535	CDK5	S15	P13L	13	Missense	proximal	-2	no	11.612	11.197	EPSD;PhosphoSitePlus	COSMIC	8.808	Down-regulation
CMGC_CDK_CDK5_CDK5_ST	P04637	TP53	Q00535	CDK5	S15	V10G	10	Missense	distal	-5	no	11.612	11.497	EPSD;PhosphoSitePlus	COSMIC	8.808	Down-regulation
CMGC_CDK_CDK5_CDK5_ST	P04637	TP53	Q00535	CDK5	S15	T18A	18	Missense	distal	3	no	11.612	10.831	EPSD;PhosphoSitePlus	COSMIC	8.808	Down-regulation
CMGC_CDK_CDK5_CDK5_ST	P04637	TP53	Q00535	CDK5	S15	F19S	19	Missense	distal	4	no	11.612	11.724	EPSD;PhosphoSitePlus	COSMIC	8.808	Up-regulation
CMGC_CDK_CDK5_CDK5_ST	P04637	TP53	Q00535	CDK5	S15	E17V	17	Missense	proximal	2	no	11.612	11.700	EPSD;PhosphoSitePlus	COSMIC	8.808	Up-regulation
CMGC_CDK_CDK5_CDK5_ST	P04637	TP53	Q00535	CDK5	S15	S9G	9	Missense	distal	-6	no	11.612	11.517	EPSD;PhosphoSitePlus	COSMIC	8.808	Down-regulation
CMGC_CDK_CDK5_CDK5_ST	P04637	TP53	Q00535	CDK5	S15	T18I	18	Missense	distal	3	no	11.612	10.634	EPSD;PhosphoSitePlus	COSMIC	8.808	Down-regulation
CMGC_CDK_CDK5_CDK5_ST	P04637	TP53	Q00535	CDK5	S15	T18K	18	Missense	distal	3	no	11.612	12.793	EPSD;PhosphoSitePlus	COSMIC	8.808	Up-regulation
CMGC_CDK_CDK5_CDK5_ST	P04637	TP53	Q00535	CDK5	S15	T18R	18	Missense	distal	3	no	11.612	12.474	EPSD;PhosphoSitePlus	COSMIC	8.808	Up-regulation
CMGC_CDK_CDK5_CDK5_ST	P04637	TP53	Q00535	CDK5	S15	S15I	15	Missense	central	0	yes	11.612	0.000	EPSD;PhosphoSitePlus	COSMIC	8.808	Loss
CMGC_CDK_CDK5_CDK5_ST	P04637	TP53	Q00535	CDK5	S33	M40I	40	Missense	distal	7	no	17.666	17.674	EPSD;PhosphoSitePlus	COSMIC	8.808	Up-regulation
CMGC_CDK_CDK5_CDK5_ST	P04637	TP53	Q00535	CDK5	S33	V31I	31	Missense	proximal	-2	no	17.666	17.525	EPSD;PhosphoSitePlus	COSMIC;GDSC;CCLE	8.808	Down-regulation
CMGC_CDK_CDK5_CDK5_ST	P04637	TP53	Q00535	CDK5	S33	P36L	36	Missense	distal	3	no	17.666	16.594	EPSD;PhosphoSitePlus	COSMIC;GDSC;CCLE	8.808	Down-regulation
CMGC_CDK_CDK5_CDK5_ST	P04637	TP53	Q00535	CDK5	S33	L35F	35	Missense	proximal	2	no	17.666	17.604	EPSD;PhosphoSitePlus	COSMIC	8.808	Down-regulation
CMGC_CDK_CDK5_CDK5_ST	P04637	TP53	Q00535	CDK5	S33	Q38L	38	Missense	distal	5	no	17.666	17.543	EPSD;PhosphoSitePlus	COSMIC	8.808	Down-regulation
CMGC_CDK_CDK5_CDK5_ST	P04637	TP53	Q00535	CDK5	S33	S37T	37	Missense	distal	4	no	17.666	17.664	EPSD;PhosphoSitePlus	COSMIC	8.808	Down-regulation
CMGC_CDK_CDK5_CDK5_ST	P04637	TP53	Q00535	CDK5	S33	L26P	26	Missense	distal	-7	no	17.666	17.718	EPSD;PhosphoSitePlus	COSMIC	8.808	Up-regulation
CMGC_CDK_CDK5_CDK5_ST	P04637	TP53	Q00535	CDK5	S33	P36S	36	Missense	distal	3	no	17.666	17.646	EPSD;PhosphoSitePlus	COSMIC;GDSC;CCLE	8.808	Down-regulation
CMGC_CDK_CDK5_CDK5_ST	P04637	TP53	Q00535	CDK5	S33	A39V	39	Missense	distal	6	no	17.666	17.675	EPSD;PhosphoSitePlus	COSMIC	8.808	Up-regulation
CMGC_CDK_CDK5_CDK5_ST	P04637	TP53	Q00535	CDK5	S33	A39S	39	Missense	distal	6	no	17.666	17.678	EPSD;PhosphoSitePlus	COSMIC	8.808	Up-regulation
CMGC_CDK_CDK5_CDK5_ST	P04637	TP53	Q00535	CDK5	S33	N30K	30	Missense	distal	-3	no	17.666	17.718	EPSD;PhosphoSitePlus	COSMIC	8.808	Up-regulation
CMGC_CDK_CDK5_CDK5_ST	P04637	TP53	Q00535	CDK5	S33	A39T	39	Missense	distal	6	no	17.666	17.678	EPSD;PhosphoSitePlus	COSMIC	8.808	Up-regulation
CMGC_CDK_CDK5_CDK5_ST	P04637	TP53	Q00535	CDK5	S33	P27T	27	Missense	distal	-6	no	17.666	17.677	EPSD;PhosphoSitePlus	COSMIC	8.808	Up-regulation
CMGC_CDK_CDK5_CDK5_ST	P04637	TP53	Q00535	CDK5	S33	P36R	36	Missense	distal	3	no	17.666	19.064	EPSD;PhosphoSitePlus	COSMIC	8.808	Up-regulation
CMGC_CDK_CDK5_CDK5_ST	P04637	TP53	Q00535	CDK5	S33	L35R	35	Missense	proximal	2	no	17.666	17.913	EPSD;PhosphoSitePlus	COSMIC	8.808	Up-regulation
CMGC_CDK_CDK5_CDK5_ST	P04637	TP53	Q00535	CDK5	S33	L35H	35	Missense	proximal	2	no	17.666	17.798	EPSD;PhosphoSitePlus	COSMIC	8.808	Up-regulation
CMGC_CDK_CDK5_CDK5_ST	P04637	TP53	Q00535	CDK5	S33	L35P	35	Missense	proximal	2	no	17.666	17.831	EPSD;PhosphoSitePlus	COSMIC	8.808	Up-regulation
CMGC_CDK_CDK5_CDK5_ST	P04637	TP53	Q00535	CDK5	S33	L35I	35	Missense	proximal	2	no	17.666	17.744	EPSD;PhosphoSitePlus	COSMIC	8.808	Up-regulation
CMGC_CDK_CDK5_CDK5_ST	P04637	TP53	Q00535	CDK5	S33	L35V	35	Missense	proximal	2	no	17.666	17.800	EPSD;PhosphoSitePlus	COSMIC	8.808	Up-regulation
CMGC_CDK_CDK5_CDK5_ST	P04637	TP53	Q00535	CDK5	S46	M40I	40	Missense	distal	-6	no	17.016	17.092	PhosphoSitePlus;EPSD	COSMIC	8.808	Up-regulation
CMGC_CDK_CDK5_CDK5_ST	P04637	TP53	Q00535	CDK5	S46	W53C	53	Missense	distal	7	no	17.016	17.010	PhosphoSitePlus;EPSD	COSMIC	8.808	Down-regulation
CMGC_CDK_CDK5_CDK5_ST	P04637	TP53	Q00535	CDK5	S46	W53G	53	Missense	distal	7	no	17.016	17.015	PhosphoSitePlus;EPSD	COSMIC	8.808	Down-regulation
CMGC_CDK_CDK5_CDK5_ST	P04637	TP53	Q00535	CDK5	S46	S46F	46	Missense	central	0	yes	17.016	0.000	PhosphoSitePlus;EPSD	COSMIC	8.808	Loss
CMGC_CDK_CDK5_CDK5_ST	P04637	TP53	Q00535	CDK5	S46	D49Y	49	Missense	distal	3	no	17.016	16.862	PhosphoSitePlus;EPSD	COSMIC	8.808	Down-regulation
CMGC_CDK_CDK5_CDK5_ST	P04637	TP53	Q00535	CDK5	S46	P47L	47	Missense	proximal	1	no	17.016	5.066	PhosphoSitePlus;EPSD	COSMIC	8.808	Loss
CMGC_CDK_CDK5_CDK5_ST	P04637	TP53	Q00535	CDK5	S46	D49H	49	Missense	distal	3	no	17.016	18.029	PhosphoSitePlus;EPSD	COSMIC;GDSC;CCLE	8.808	Up-regulation
CMGC_CDK_CDK5_CDK5_ST	P04637	TP53	Q00535	CDK5	S46	P47S	47	Missense	proximal	1	no	17.016	5.115	PhosphoSitePlus;EPSD	COSMIC	8.808	Loss
CMGC_CDK_CDK5_CDK5_ST	P04637	TP53	Q00535	CDK5	S46	D41N	41	Missense	distal	-5	no	17.016	17.090	PhosphoSitePlus;EPSD	COSMIC	8.808	Up-regulation
CMGC_CDK_CDK5_CDK5_ST	P04637	TP53	Q00535	CDK5	S46	D48H	48	Missense	proximal	2	no	17.016	17.106	PhosphoSitePlus;EPSD	COSMIC	8.808	Up-regulation
CMGC_CDK_CDK5_CDK5_ST	P04637	TP53	Q00535	CDK5	S46	D49N	49	Missense	distal	3	no	17.016	17.435	PhosphoSitePlus;EPSD	COSMIC	8.808	Up-regulation
CMGC_CDK_CDK5_CDK5_ST	P04637	TP53	Q00535	CDK5	S46	M44I	44	Missense	proximal	-2	no	17.016	17.267	PhosphoSitePlus;EPSD	COSMIC	8.808	Up-regulation
CMGC_CDK_CDK5_CDK5_ST	P04637	TP53	Q00535	CDK5	S46	D49V	49	Missense	distal	3	no	17.016	17.657	PhosphoSitePlus;EPSD	COSMIC	8.808	Up-regulation
CMGC_CDK_CDK5_CDK5_ST	P04637	TP53	Q00535	CDK5	S46	A39V	39	Missense	distal	-7	no	17.016	17.052	PhosphoSitePlus;EPSD	COSMIC	8.808	Up-regulation
CMGC_CDK_CDK5_CDK5_ST	P04637	TP53	Q00535	CDK5	S46	A39S	39	Missense	distal	-7	no	17.016	17.070	PhosphoSitePlus;EPSD	COSMIC	8.808	Up-regulation
CMGC_CDK_CDK5_CDK5_ST	P04637	TP53	Q00535	CDK5	S46	D42Y	42	Missense	distal	-4	no	17.016	16.712	PhosphoSitePlus;EPSD	COSMIC	8.808	Down-regulation
CMGC_CDK_CDK5_CDK5_ST	P04637	TP53	Q00535	CDK5	S46	M44R	44	Missense	proximal	-2	no	17.016	17.534	PhosphoSitePlus;EPSD	COSMIC	8.808	Up-regulation
CMGC_CDK_CDK5_CDK5_ST	P04637	TP53	Q00535	CDK5	S46	S46P	46	Missense	central	0	yes	17.016	0.000	PhosphoSitePlus;EPSD	COSMIC	8.808	Loss
CMGC_CDK_CDK5_CDK5_ST	P04637	TP53	Q00535	CDK5	S46	M44V	44	Missense	proximal	-2	no	17.016	17.408	PhosphoSitePlus;EPSD	COSMIC	8.808	Up-regulation
CMGC_CDK_CDK5_CDK5_ST	P04637	TP53	Q00535	CDK5	S46	L45P	45	Missense	proximal	-1	no	17.016	17.021	PhosphoSitePlus;EPSD	COSMIC	8.808	Up-regulation
CMGC_CDK_CDK5_CDK5_ST	P04637	TP53	Q00535	CDK5	S46	M44T	44	Missense	proximal	-2	no	17.016	17.449	PhosphoSitePlus;EPSD	COSMIC	8.808	Up-regulation
CMGC_CDK_CDK5_CDK5_ST	P04637	TP53	Q00535	CDK5	S46	A39T	39	Missense	distal	-7	no	17.016	17.055	PhosphoSitePlus;EPSD	COSMIC	8.808	Up-regulation
CMGC_CDK_CDK5_CDK5_ST	P04637	TP53	Q00535	CDK5	S46	L43F	43	Missense	distal	-3	no	17.016	16.994	PhosphoSitePlus;EPSD	COSMIC	8.808	Down-regulation
CMGC_CDK_CDK5_CDK5_ST	P04637	TP53	Q00535	CDK5	S46	D41H	41	Missense	distal	-5	no	17.016	17.089	PhosphoSitePlus;EPSD	COSMIC	8.808	Up-regulation
CMGC_CDK_CDK5_CDK5_ST	P04637	TP53	Q00535	CDK5	S46	D49E	49	Missense	distal	3	no	17.016	17.082	PhosphoSitePlus;EPSD	COSMIC	8.808	Up-regulation
CMGC_CDK_CDK5_CDK5_ST	P04637	TP53	Q00535	CDK5	S46	D49G	49	Missense	distal	3	no	17.016	17.667	PhosphoSitePlus;EPSD	COSMIC	8.808	Up-regulation
CMGC_CDK_CDK5_CDK5_ST	P04637	TP53	Q00535	CDK5	S46	D48A	48	Missense	proximal	2	no	17.016	17.028	PhosphoSitePlus;EPSD	COSMIC	8.808	Up-regulation
CMGC_CDK_CDK5_CDK5_ST	P04637	TP53	Q00535	CDK5	S46	D48Y	48	Missense	proximal	2	no	17.016	16.971	PhosphoSitePlus;EPSD	COSMIC	8.808	Down-regulation
CMGC_CDK_CDK5_CDK5_ST	P04637	TP53	Q00535	CDK5	S46	D48E	48	Missense	proximal	2	no	17.016	17.020	PhosphoSitePlus;EPSD	COSMIC	8.808	Up-regulation
CMGC_CDK_CDK5_CDK5_ST	P04637	TP53	Q00535	CDK5	S46	D49I	49	Missense	distal	3	no	17.016	17.209	PhosphoSitePlus;EPSD	COSMIC	8.808	Up-regulation
CMGC_CDK_CDK5_CDK5_ST	P04637	TP53	Q00535	CDK5	S46	D41E	41	Missense	distal	-5	no	17.016	17.006	PhosphoSitePlus;EPSD	COSMIC	8.808	Down-regulation
CMGC_CDK_CDK5_CDK5_ST	P04637	TP53	Q00535	CDK5	T81	P77A	77	Missense	distal	-4	no	16.829	16.273	EPSD	COSMIC	8.808	Down-regulation
CMGC_CDK_CDK5_CDK5_ST	P04637	TP53	Q00535	CDK5	T81	A76T	76	Missense	distal	-5	no	16.829	16.985	EPSD	COSMIC	8.808	Up-regulation
CMGC_CDK_CDK5_CDK5_ST	P04637	TP53	Q00535	CDK5	T81	A83T	83	Missense	proximal	2	no	16.829	16.948	EPSD	COSMIC	8.808	Up-regulation
CMGC_CDK_CDK5_CDK5_ST	P04637	TP53	Q00535	CDK5	T81	T81I	81	Missense	central	0	yes	16.829	0.000	EPSD	COSMIC	8.808	Loss
CMGC_CDK_CDK5_CDK5_ST	P04637	TP53	Q00535	CDK5	T81	A84V	84	Missense	distal	3	no	16.829	17.081	EPSD	COSMIC	8.808	Up-regulation
CMGC_CDK_CDK5_CDK5_ST	P04637	TP53	Q00535	CDK5	T81	P80L	80	Missense	proximal	-1	no	16.829	16.824	EPSD	COSMIC	8.808	Down-regulation
CMGC_CDK_CDK5_CDK5_ST	P04637	TP53	Q00535	CDK5	T81	A86V	86	Missense	distal	5	no	16.829	16.926	EPSD	COSMIC	8.808	Up-regulation
CMGC_CDK_CDK5_CDK5_ST	P04637	TP53	Q00535	CDK5	T81	P85S	85	Missense	distal	4	no	16.829	16.831	EPSD	COSMIC	8.808	Up-regulation
CMGC_CDK_CDK5_CDK5_ST	P04637	TP53	Q00535	CDK5	T81	A79T	79	Missense	proximal	-2	no	16.829	17.067	EPSD	COSMIC	8.808	Up-regulation
CMGC_CDK_CDK5_CDK5_ST	P04637	TP53	Q00535	CDK5	T81	A84G	84	Missense	distal	3	no	16.829	17.090	EPSD	COSMIC	8.808	Up-regulation
CMGC_CDK_CDK5_CDK5_ST	P04637	TP53	Q00535	CDK5	T81	A78V	78	Missense	distal	-3	no	16.829	16.867	EPSD	COSMIC	8.808	Up-regulation
CMGC_CDK_CDK5_CDK5_ST	P04637	TP53	Q00535	CDK5	T81	A78S	78	Missense	distal	-3	no	16.829	16.876	EPSD	COSMIC	8.808	Up-regulation
CMGC_CDK_CDK5_CDK5_ST	P04637	TP53	Q00535	CDK5	T81	P87L	87	Missense	distal	6	no	16.829	16.815	EPSD	COSMIC	8.808	Down-regulation
CMGC_CDK_CDK5_CDK5_ST	P04637	TP53	Q00535	CDK5	T81	P85L	85	Missense	distal	4	no	16.829	16.748	EPSD	COSMIC	8.808	Down-regulation
CMGC_CDK_CDK5_CDK5_ST	P04637	TP53	Q00535	CDK5	T81	P82S	82	Missense	proximal	1	no	16.829	4.928	EPSD	COSMIC	8.808	Loss
CMGC_CDK_CDK5_CDK5_ST	P04637	TP53	Q00535	CDK5	T81	P77S	77	Missense	distal	-4	no	16.829	17.175	EPSD	COSMIC	8.808	Up-regulation
CMGC_CDK_CDK5_CDK5_ST	P04637	TP53	Q00535	CDK5	T81	P80S	80	Missense	proximal	-1	no	16.829	16.830	EPSD	COSMIC	8.808	Up-regulation
CMGC_CDK_CDK5_CDK5_ST	P04637	TP53	Q00535	CDK5	T81	A84T	84	Missense	distal	3	no	16.829	17.610	EPSD	COSMIC	8.808	Up-regulation
CMGC_CDK_CDK5_CDK5_ST	P04637	TP53	Q00535	CDK5	T81	A83E	83	Missense	proximal	2	no	16.829	16.821	EPSD	COSMIC	8.808	Down-regulation
CMGC_CDK_CDK5_CDK5_ST	P04637	TP53	Q00535	CDK5	T81	P85T	85	Missense	distal	4	no	16.829	16.828	EPSD	COSMIC	8.808	Down-regulation
CMGC_CDK_CDK5_CDK5_ST	P04637	TP53	Q00535	CDK5	T81	A74V	74	Missense	distal	-7	no	16.829	16.865	EPSD	COSMIC	8.808	Up-regulation
CMGC_CDK_CDK5_CDK5_ST	P04637	TP53	Q00535	CDK5	T81	P75S	75	Missense	distal	-6	no	16.829	16.868	EPSD	COSMIC	8.808	Up-regulation
CMGC_CDK_CDK5_CDK5_ST	P04637	TP53	Q00535	CDK5	T81	A76V	76	Missense	distal	-5	no	16.829	16.954	EPSD	COSMIC	8.808	Up-regulation
CMGC_CDK_CDK5_CDK5_ST	P04637	TP53	Q00535	CDK5	T81	P75R	75	Missense	distal	-6	no	16.829	16.874	EPSD	COSMIC	8.808	Up-regulation
CMGC_CDK_CDK5_CDK5_ST	P04637	TP53	Q00535	CDK5	T81	P87H	87	Missense	distal	6	no	16.829	16.826	EPSD	COSMIC	8.808	Down-regulation
CMGC_CDK_CDK5_CDK5_ST	P04637	TP53	Q00535	CDK5	T81	P87T	87	Missense	distal	6	no	16.829	16.830	EPSD	COSMIC	8.808	Up-regulation
CMGC_CDK_CDK5_CDK5_ST	P04637	TP53	Q00535	CDK5	T81	P87S	87	Missense	distal	6	no	16.829	16.830	EPSD	COSMIC	8.808	Up-regulation
CMGC_CDK_CDK5_CDK5_ST	P04637	TP53	Q00535	CDK5	T81	P87R	87	Missense	distal	6	no	16.829	16.837	EPSD	COSMIC	8.808	Up-regulation
CMGC_CDK_CDK5_CDK5_ST	P04637	TP53	Q00535	CDK5	T81	P87C	87	Missense	distal	6	no	16.829	16.813	EPSD	COSMIC	8.808	Down-regulation
CMGC_CDK_CDK5_CDK5_ST	P04637	TP53	Q00535	CDK5	T81	A86E	86	Missense	distal	5	no	16.829	16.850	EPSD	COSMIC	8.808	Up-regulation
CMGC_CDK_CDK5_CDK5_ST	P04637	TP53	Q00535	CDK5	T81	A86S	86	Missense	distal	5	no	16.829	16.963	EPSD	COSMIC	8.808	Up-regulation
CMGC_CDK_CDK5_CDK5_ST	P04637	TP53	Q00535	CDK5	T81	A83V	83	Missense	proximal	2	no	16.829	16.910	EPSD	COSMIC	8.808	Up-regulation
CMGC_CDK_CDK5_CDK5_ST	P04637	TP53	Q00535	CDK5	S99	S99F	99	Missense	central	0	yes	10.461	0.000	EPSD	COSMIC	8.808	Loss
CMGC_CDK_CDK5_CDK5_ST	P04637	TP53	Q00535	CDK5	S99	S96F	96	Missense	distal	-3	no	10.461	10.384	EPSD	COSMIC	8.808	Down-regulation
CMGC_CDK_CDK5_CDK5_ST	P04637	TP53	Q00535	CDK5	S99	P98S	98	Missense	proximal	-1	no	10.461	10.462	EPSD	COSMIC;CCLE	8.808	Up-regulation
CMGC_CDK_CDK5_CDK5_ST	P04637	TP53	Q00535	CDK5	S99	T102I	102	Missense	distal	3	no	10.461	9.483	EPSD	COSMIC	8.808	Down-regulation
CMGC_CDK_CDK5_CDK5_ST	P04637	TP53	Q00535	CDK5	S99	S94P	94	Missense	distal	-5	no	10.461	10.439	EPSD	COSMIC	8.808	Down-regulation
CMGC_CDK_CDK5_CDK5_ST	P04637	TP53	Q00535	CDK5	S99	K101R	101	Missense	proximal	2	no	10.461	10.412	EPSD	COSMIC	8.808	Down-regulation
CMGC_CDK_CDK5_CDK5_ST	P04637	TP53	Q00535	CDK5	S99	S94T	94	Missense	distal	-5	no	10.461	10.436	EPSD	COSMIC	8.808	Down-regulation
CMGC_CDK_CDK5_CDK5_ST	P04637	TP53	Q00535	CDK5	S99	P98L	98	Missense	proximal	-1	no	10.461	10.456	EPSD	COSMIC;GDSC;CCLE	8.808	Down-regulation
CMGC_CDK_CDK5_CDK5_ST	P04637	TP53	Q00535	CDK5	S99	S95F	95	Missense	distal	-4	no	10.461	9.300	EPSD	COSMIC;CCLE	8.808	Down-regulation
CMGC_CDK_CDK5_CDK5_ST	P04637	TP53	Q00535	CDK5	S99	S96C	96	Missense	distal	-3	no	10.461	10.398	EPSD	COSMIC	8.808	Down-regulation
CMGC_CDK_CDK5_CDK5_ST	P04637	TP53	Q00535	CDK5	S99	S106I	106	Missense	distal	7	no	10.461	10.455	EPSD	COSMIC	8.808	Down-regulation
CMGC_CDK_CDK5_CDK5_ST	P04637	TP53	Q00535	CDK5	S99	P98F	98	Missense	proximal	-1	no	10.461	10.454	EPSD	COSMIC	8.808	Down-regulation
CMGC_CDK_CDK5_CDK5_ST	P04637	TP53	Q00535	CDK5	S99	T102P	102	Missense	distal	3	no	10.461	9.925	EPSD	COSMIC	8.808	Down-regulation
CMGC_CDK_CDK5_CDK5_ST	P04637	TP53	Q00535	CDK5	S99	S94L	94	Missense	distal	-5	no	10.461	10.241	EPSD	COSMIC	8.808	Down-regulation
CMGC_CDK_CDK5_CDK5_ST	P04637	TP53	Q00535	CDK5	S99	S96P	96	Missense	distal	-3	no	10.461	10.467	EPSD	COSMIC	8.808	Up-regulation
CMGC_CDK_CDK5_CDK5_ST	P04637	TP53	Q00535	CDK5	S99	S96Y	96	Missense	distal	-3	no	10.461	10.404	EPSD	COSMIC	8.808	Down-regulation
CMGC_CDK_CDK5_CDK5_ST	P04637	TP53	Q00535	CDK5	S99	S99P	99	Missense	central	0	yes	10.461	0.000	EPSD	COSMIC	8.808	Loss
CMGC_CDK_CDK5_CDK5_ST	P04637	TP53	Q00535	CDK5	S99	V97I	97	Missense	proximal	-2	no	10.461	10.321	EPSD	COSMIC	8.808	Down-regulation
CMGC_CDK_CDK5_CDK5_ST	P04637	TP53	Q00535	CDK5	S99	Q104H	104	Missense	distal	5	no	10.461	10.483	EPSD	COSMIC	8.808	Up-regulation
CMGC_CDK_CDK5_CDK5_ST	P04637	TP53	Q00535	CDK5	S99	L93M	93	Missense	distal	-6	no	10.461	10.434	EPSD	COSMIC	8.808	Down-regulation
CMGC_CDK_CDK5_CDK5_ST	P04637	TP53	Q00535	CDK5	S99	K101N	101	Missense	proximal	2	no	10.461	10.267	EPSD	COSMIC	8.808	Down-regulation
CMGC_CDK_CDK5_CDK5_ST	P04637	TP53	Q00535	CDK5	S99	V97A	97	Missense	proximal	-2	no	10.461	10.265	EPSD	COSMIC	8.808	Down-regulation
CMGC_CDK_CDK5_CDK5_ST	P04637	TP53	Q00535	CDK5	S99	P92A	92	Missense	distal	-7	no	10.461	10.412	EPSD	COSMIC	8.808	Down-regulation
CMGC_CDK_CDK5_CDK5_ST	P04637	TP53	Q00535	CDK5	S99	Q104L	104	Missense	distal	5	no	10.461	10.338	EPSD	COSMIC	8.808	Down-regulation
CMGC_CDK_CDK5_CDK5_ST	P04637	TP53	Q00535	CDK5	S99	P92L	92	Missense	distal	-7	no	10.461	10.409	EPSD	COSMIC	8.808	Down-regulation
CMGC_CDK_CDK5_CDK5_ST	P04637	TP53	Q00535	CDK5	S99	L93P	93	Missense	distal	-6	no	10.461	10.544	EPSD	COSMIC	8.808	Up-regulation
CMGC_CDK_CDK5_CDK5_ST	P04637	TP53	Q00535	CDK5	S99	L93F	93	Missense	distal	-6	no	10.461	10.410	EPSD	COSMIC	8.808	Down-regulation
CMGC_CDK_CDK5_CDK5_ST	P04637	TP53	Q00535	CDK5	S99	L93H	93	Missense	distal	-6	no	10.461	10.524	EPSD	COSMIC	8.808	Up-regulation
CMGC_CDK_CDK5_CDK5_ST	P04637	TP53	Q00535	CDK5	S99	S95Y	95	Missense	distal	-4	no	10.461	9.480	EPSD	COSMIC	8.808	Down-regulation
CMGC_CDK_CDK5_CDK5_ST	P04637	TP53	Q00535	CDK5	S127	C124W	124	Missense	distal	-3	no	16.799	16.824	EPSD	COSMIC	8.808	Up-regulation
CMGC_CDK_CDK5_CDK5_ST	P04637	TP53	Q00535	CDK5	S127	C124F	124	Missense	distal	-3	no	16.799	16.786	EPSD	COSMIC	8.808	Down-regulation
CMGC_CDK_CDK5_CDK5_ST	P04637	TP53	Q00535	CDK5	S127	C124S	124	Missense	distal	-3	no	16.799	16.863	EPSD	COSMIC	8.808	Up-regulation
CMGC_CDK_CDK5_CDK5_ST	P04637	TP53	Q00535	CDK5	S127	S127A	127	Missense	central	0	yes	16.799	0.000	EPSD	COSMIC	8.808	Loss
CMGC_CDK_CDK5_CDK5_ST	P04637	TP53	Q00535	CDK5	S127	S127L	127	Missense	central	0	yes	16.799	0.000	EPSD	COSMIC	8.808	Loss
CMGC_CDK_CDK5_CDK5_ST	P04637	TP53	Q00535	CDK5	S127	C124T	124	Missense	distal	-3	no	16.799	16.861	EPSD	COSMIC	8.808	Up-regulation
CMGC_CDK_CDK5_CDK5_ST	P04637	TP53	Q00535	CDK5	S127	S127I	127	Missense	central	0	yes	16.799	0.000	EPSD	COSMIC	8.808	Loss
CMGC_CDK_CDK5_CDK5_ST	P04637	TP53	Q00535	CDK5	S127	S127G	127	Missense	central	0	yes	16.799	0.000	EPSD	COSMIC	8.808	Loss
CMGC_CDK_CDK5_CDK5_ST	P04637	TP53	Q00535	CDK5	S127	N131H	131	Missense	distal	4	no	16.799	16.807	EPSD	COSMIC	8.808	Up-regulation
CMGC_CDK_CDK5_CDK5_ST	P04637	TP53	Q00535	CDK5	S127	N131D	131	Missense	distal	4	no	16.799	16.769	EPSD	COSMIC	8.808	Down-regulation
CMGC_CDK_CDK5_CDK5_ST	P04637	TP53	Q00535	CDK5	S127	T125I	125	Missense	proximal	-2	no	16.799	16.617	EPSD	COSMIC	8.808	Down-regulation
CMGC_CDK_CDK5_CDK5_ST	P04637	TP53	Q00535	CDK5	S127	F134I	134	Missense	distal	7	no	16.799	16.810	EPSD	COSMIC	8.808	Up-regulation
CMGC_CDK_CDK5_CDK5_ST	P04637	TP53	Q00535	CDK5	S127	K120T	120	Missense	distal	-7	no	16.799	16.768	EPSD	COSMIC	8.808	Down-regulation
CMGC_CDK_CDK5_CDK5_ST	P04637	TP53	Q00535	CDK5	S127	F134S	134	Missense	distal	7	no	16.799	16.817	EPSD	COSMIC	8.808	Up-regulation
CMGC_CDK_CDK5_CDK5_ST	P04637	TP53	Q00535	CDK5	S127	T125K	125	Missense	proximal	-2	no	16.799	16.910	EPSD	COSMIC	8.808	Up-regulation
CMGC_CDK_CDK5_CDK5_ST	P04637	TP53	Q00535	CDK5	S127	M133I	133	Missense	distal	6	no	16.799	16.810	EPSD	COSMIC	8.808	Up-regulation
CMGC_CDK_CDK5_CDK5_ST	P04637	TP53	Q00535	CDK5	S127	N131K	131	Missense	distal	4	no	16.799	16.894	EPSD	COSMIC;CCLE	8.808	Up-regulation
CMGC_CDK_CDK5_CDK5_ST	P04637	TP53	Q00535	CDK5	S127	P128S	128	Missense	proximal	1	no	16.799	4.898	EPSD	COSMIC	8.808	Loss
CMGC_CDK_CDK5_CDK5_ST	P04637	TP53	Q00535	CDK5	S127	M133L	133	Missense	distal	6	no	16.799	16.801	EPSD	COSMIC	8.808	Up-regulation
CMGC_CDK_CDK5_CDK5_ST	P04637	TP53	Q00535	CDK5	S127	A129T	129	Missense	proximal	2	no	16.799	16.918	EPSD	COSMIC	8.808	Up-regulation
CMGC_CDK_CDK5_CDK5_ST	P04637	TP53	Q00535	CDK5	S127	T123I	123	Missense	distal	-4	no	16.799	16.686	EPSD	COSMIC	8.808	Down-regulation
CMGC_CDK_CDK5_CDK5_ST	P04637	TP53	Q00535	CDK5	S127	A129G	129	Missense	proximal	2	no	16.799	16.820	EPSD	COSMIC	8.808	Up-regulation
CMGC_CDK_CDK5_CDK5_ST	P04637	TP53	Q00535	CDK5	S127	K132W	132	Missense	distal	5	no	16.799	16.547	EPSD	COSMIC	8.808	Down-regulation
CMGC_CDK_CDK5_CDK5_ST	P04637	TP53	Q00535	CDK5	S127	A129V	129	Missense	proximal	2	no	16.799	16.880	EPSD	COSMIC	8.808	Up-regulation
CMGC_CDK_CDK5_CDK5_ST	P04637	TP53	Q00535	CDK5	S127	P128A	128	Missense	proximal	1	no	16.799	5.773	EPSD	COSMIC	8.808	Loss
CMGC_CDK_CDK5_CDK5_ST	P04637	TP53	Q00535	CDK5	S127	L130I	130	Missense	distal	3	no	16.799	17.430	EPSD	COSMIC	8.808	Up-regulation
CMGC_CDK_CDK5_CDK5_ST	P04637	TP53	Q00535	CDK5	S127	S121F	121	Missense	distal	-6	no	16.799	16.626	EPSD	COSMIC	8.808	Down-regulation
CMGC_CDK_CDK5_CDK5_ST	P04637	TP53	Q00535	CDK5	S127	A129D	129	Missense	proximal	2	no	16.799	16.788	EPSD	COSMIC	8.808	Down-regulation
CMGC_CDK_CDK5_CDK5_ST	P04637	TP53	Q00535	CDK5	S127	K120Q	120	Missense	distal	-7	no	16.799	16.762	EPSD	COSMIC	8.808	Down-regulation
CMGC_CDK_CDK5_CDK5_ST	P04637	TP53	Q00535	CDK5	S127	T125S	125	Missense	proximal	-2	no	16.799	16.840	EPSD	COSMIC	8.808	Up-regulation
CMGC_CDK_CDK5_CDK5_ST	P04637	TP53	Q00535	CDK5	S127	P128L	128	Missense	proximal	1	no	16.799	4.850	EPSD	COSMIC	8.808	Loss
CMGC_CDK_CDK5_CDK5_ST	P04637	TP53	Q00535	CDK5	S127	V122L	122	Missense	distal	-5	no	16.799	16.636	EPSD	COSMIC	8.808	Down-regulation
CMGC_CDK_CDK5_CDK5_ST	P04637	TP53	Q00535	CDK5	S127	C124L	124	Missense	distal	-3	no	16.799	16.808	EPSD	COSMIC	8.808	Up-regulation
CMGC_CDK_CDK5_CDK5_ST	P04637	TP53	Q00535	CDK5	S127	N131T	131	Missense	distal	4	no	16.799	16.828	EPSD	COSMIC	8.808	Up-regulation
CMGC_CDK_CDK5_CDK5_ST	P04637	TP53	Q00535	CDK5	S127	M133V	133	Missense	distal	6	no	16.799	16.813	EPSD	COSMIC	8.808	Up-regulation
CMGC_CDK_CDK5_CDK5_ST	P04637	TP53	Q00535	CDK5	S149	P152K	152	Missense	distal	3	no	7.463	9.180	EPSD	COSMIC	8.808	Gain
CMGC_CDK_CDK5_CDK5_ST	P04637	TP53	Q00535	CDK5	S149	T150R	150	Missense	proximal	1	no	7.463	9.003	EPSD	COSMIC	8.808	Gain
CMGC_CDK_CDK5_CDK5_ST	P04637	TP53	Q00535	CDK5	T150	P151N	151	Missense	proximal	1	no	16.442	7.203	EPSD	COSMIC	8.808	Loss
CMGC_CDK_CDK5_CDK5_ST	P04637	TP53	Q00535	CDK5	T150	P152A	152	Missense	proximal	2	no	16.442	16.330	EPSD	COSMIC	8.808	Down-regulation
CMGC_CDK_CDK5_CDK5_ST	P04637	TP53	Q00535	CDK5	T150	P152T	152	Missense	proximal	2	no	16.442	16.449	EPSD	COSMIC	8.808	Up-regulation
CMGC_CDK_CDK5_CDK5_ST	P04637	TP53	Q00535	CDK5	T150	P152H	152	Missense	proximal	2	no	16.442	16.409	EPSD	COSMIC	8.808	Down-regulation
CMGC_CDK_CDK5_CDK5_ST	P04637	TP53	Q00535	CDK5	T150	P153T	153	Missense	distal	3	no	16.442	16.978	EPSD	COSMIC	8.808	Up-regulation
CMGC_CDK_CDK5_CDK5_ST	P04637	TP53	Q00535	CDK5	T150	V147I	147	Missense	distal	-3	no	16.442	16.427	EPSD	COSMIC	8.808	Down-regulation
CMGC_CDK_CDK5_CDK5_ST	P04637	TP53	Q00535	CDK5	T150	P153L	153	Missense	distal	3	no	16.442	15.370	EPSD	COSMIC	8.808	Down-regulation
CMGC_CDK_CDK5_CDK5_ST	P04637	TP53	Q00535	CDK5	T150	V147D	147	Missense	distal	-3	no	16.442	16.410	EPSD	COSMIC;GDSC;CCLE	8.808	Down-regulation
CMGC_CDK_CDK5_CDK5_ST	P04637	TP53	Q00535	CDK5	T150	S149P	149	Missense	proximal	-1	no	16.442	16.441	EPSD	COSMIC	8.808	Down-regulation
CMGC_CDK_CDK5_CDK5_ST	P04637	TP53	Q00535	CDK5	T150	P152K	152	Missense	proximal	2	no	16.442	16.573	EPSD	COSMIC	8.808	Up-regulation
CMGC_CDK_CDK5_CDK5_ST	P04637	TP53	Q00535	CDK5	T150	P153S	153	Missense	distal	3	no	16.442	16.422	EPSD	COSMIC	8.808	Down-regulation
CMGC_CDK_CDK5_CDK5_ST	P04637	TP53	Q00535	CDK5	T150	G154C	154	Missense	distal	4	no	16.442	16.402	EPSD	COSMIC	8.808	Down-regulation
CMGC_CDK_CDK5_CDK5_ST	P04637	TP53	Q00535	CDK5	T150	S149F	149	Missense	proximal	-1	no	16.442	16.434	EPSD	COSMIC	8.808	Down-regulation
CMGC_CDK_CDK5_CDK5_ST	P04637	TP53	Q00535	CDK5	T150	G154D	154	Missense	distal	4	no	16.442	16.432	EPSD	COSMIC	8.808	Down-regulation
CMGC_CDK_CDK5_CDK5_ST	P04637	TP53	Q00535	CDK5	T150	V157I	157	Missense	distal	7	no	16.442	16.438	EPSD	COSMIC	8.808	Down-regulation
CMGC_CDK_CDK5_CDK5_ST	P04637	TP53	Q00535	CDK5	T150	W146R	146	Missense	distal	-4	no	16.442	16.790	EPSD	COSMIC	8.808	Up-regulation
CMGC_CDK_CDK5_CDK5_ST	P04637	TP53	Q00535	CDK5	T150	Q144R	144	Missense	distal	-6	no	16.442	16.500	EPSD	COSMIC	8.808	Up-regulation
CMGC_CDK_CDK5_CDK5_ST	P04637	TP53	Q00535	CDK5	T150	D148V	148	Missense	proximal	-2	no	16.442	16.595	EPSD	COSMIC	8.808	Up-regulation
CMGC_CDK_CDK5_CDK5_ST	P04637	TP53	Q00535	CDK5	T150	S149Y	149	Missense	proximal	-1	no	16.442	16.436	EPSD	COSMIC	8.808	Down-regulation
CMGC_CDK_CDK5_CDK5_ST	P04637	TP53	Q00535	CDK5	T150	T150I	150	Missense	central	0	yes	16.442	0.000	EPSD	COSMIC	8.808	Loss
CMGC_CDK_CDK5_CDK5_ST	P04637	TP53	Q00535	CDK5	T150	S149T	149	Missense	proximal	-1	no	16.442	16.441	EPSD	COSMIC	8.808	Down-regulation
CMGC_CDK_CDK5_CDK5_ST	P04637	TP53	Q00535	CDK5	T150	W146G	146	Missense	distal	-4	no	16.442	16.411	EPSD	COSMIC	8.808	Down-regulation
CMGC_CDK_CDK5_CDK5_ST	P04637	TP53	Q00535	CDK5	T150	L145M	145	Missense	distal	-5	no	16.442	16.379	EPSD	COSMIC	8.808	Down-regulation
CMGC_CDK_CDK5_CDK5_ST	P04637	TP53	Q00535	CDK5	T150	V143L	143	Missense	distal	-7	no	16.442	16.404	EPSD	COSMIC	8.808	Down-regulation
CMGC_CDK_CDK5_CDK5_ST	P04637	TP53	Q00535	CDK5	T150	R156S	156	Missense	distal	6	no	16.442	16.435	EPSD	COSMIC	8.808	Down-regulation
CMGC_CDK_CDK5_CDK5_ST	P04637	TP53	Q00535	CDK5	T150	D148E	148	Missense	proximal	-2	no	16.442	16.334	EPSD	COSMIC	8.808	Down-regulation
CMGC_CDK_CDK5_CDK5_ST	P04637	TP53	Q00535	CDK5	T150	V147F	147	Missense	distal	-3	no	16.442	16.373	EPSD	COSMIC	8.808	Down-regulation
CMGC_CDK_CDK5_CDK5_ST	P04637	TP53	Q00535	CDK5	T150	T155A	155	Missense	distal	5	no	16.442	16.308	EPSD	COSMIC	8.808	Down-regulation
CMGC_CDK_CDK5_CDK5_ST	P04637	TP53	Q00535	CDK5	T150	V147E	147	Missense	distal	-3	no	16.442	16.413	EPSD	COSMIC	8.808	Down-regulation
CMGC_CDK_CDK5_CDK5_ST	P04637	TP53	Q00535	CDK5	T150	G154I	154	Missense	distal	4	no	16.442	16.449	EPSD	COSMIC	8.808	Up-regulation
CMGC_CDK_CDK5_CDK5_ST	P04637	TP53	Q00535	CDK5	T150	D148G	148	Missense	proximal	-2	no	16.442	16.312	EPSD	COSMIC	8.808	Down-regulation
CMGC_CDK_CDK5_CDK5_ST	P04637	TP53	Q00535	CDK5	T150	Q144K	144	Missense	distal	-6	no	16.442	16.536	EPSD	COSMIC	8.808	Up-regulation
CMGC_CDK_CDK5_CDK5_ST	P04637	TP53	Q00535	CDK5	T150	V147A	147	Missense	distal	-3	no	16.442	16.404	EPSD	COSMIC	8.808	Down-regulation
CMGC_CDK_CDK5_CDK5_ST	P04637	TP53	Q00535	CDK5	T150	L145V	145	Missense	distal	-5	no	16.442	16.605	EPSD	COSMIC	8.808	Up-regulation
CMGC_CDK_CDK5_CDK5_ST	P04637	TP53	Q00535	CDK5	T150	T150K	150	Missense	central	0	yes	16.442	0.000	EPSD	COSMIC	8.808	Loss
CMGC_CDK_CDK5_CDK5_ST	P04637	TP53	Q00535	CDK5	T150	P153H	153	Missense	distal	3	no	16.442	16.821	EPSD	COSMIC	8.808	Up-regulation
CMGC_CDK_CDK5_CDK5_ST	P04637	TP53	Q00535	CDK5	T150	V157E	157	Missense	distal	7	no	16.442	16.436	EPSD	COSMIC	8.808	Down-regulation
CMGC_CDK_CDK5_CDK5_ST	P04637	TP53	Q00535	CDK5	T150	T155S	155	Missense	distal	5	no	16.442	16.443	EPSD	COSMIC;CCLE	8.808	Up-regulation
CMGC_CDK_CDK5_CDK5_ST	P04637	TP53	Q00535	CDK5	T150	D148H	148	Missense	proximal	-2	no	16.442	16.460	EPSD	COSMIC	8.808	Up-regulation
CMGC_CDK_CDK5_CDK5_ST	P04637	TP53	Q00535	CDK5	T150	P153A	153	Missense	distal	3	no	16.442	16.198	EPSD	COSMIC	8.808	Down-regulation
CMGC_CDK_CDK5_CDK5_ST	P04637	TP53	Q00535	CDK5	T150	T150R	150	Missense	central	0	yes	16.442	0.000	EPSD	COSMIC	8.808	Loss
CMGC_CDK_CDK5_CDK5_ST	P04637	TP53	Q00535	CDK5	T150	T155L	155	Missense	distal	5	no	16.442	16.258	EPSD	COSMIC	8.808	Down-regulation
CMGC_CDK_CDK5_CDK5_ST	P04637	TP53	Q00535	CDK5	T150	G154A	154	Missense	distal	4	no	16.442	16.431	EPSD	COSMIC	8.808	Down-regulation
CMGC_CDK_CDK5_CDK5_ST	P04637	TP53	Q00535	CDK5	T150	T150A	150	Missense	central	0	yes	16.442	0.000	EPSD	COSMIC	8.808	Loss
CMGC_CDK_CDK5_CDK5_ST	P04637	TP53	Q00535	CDK5	T150	W146C	146	Missense	distal	-4	no	16.442	16.228	EPSD	COSMIC	8.808	Down-regulation
CMGC_CDK_CDK5_CDK5_ST	P04637	TP53	Q00535	CDK5	T150	P153F	153	Missense	distal	3	no	16.442	15.245	EPSD	COSMIC	8.808	Down-regulation
CMGC_CDK_CDK5_CDK5_ST	P04637	TP53	Q00535	CDK5	T150	D148Y	148	Missense	proximal	-2	no	16.442	16.248	EPSD	COSMIC	8.808	Down-regulation
CMGC_CDK_CDK5_CDK5_ST	P04637	TP53	Q00535	CDK5	T150	G154R	154	Missense	distal	4	no	16.442	16.510	EPSD	COSMIC	8.808	Up-regulation
CMGC_CDK_CDK5_CDK5_ST	P04637	TP53	Q00535	CDK5	T155	P151N	151	Missense	distal	-4	no	10.259	10.093	EPSD	COSMIC	8.808	Down-regulation
CMGC_CDK_CDK5_CDK5_ST	P04637	TP53	Q00535	CDK5	T155	P152A	152	Missense	distal	-3	no	10.259	10.207	EPSD	COSMIC	8.808	Down-regulation
CMGC_CDK_CDK5_CDK5_ST	P04637	TP53	Q00535	CDK5	T155	P152T	152	Missense	distal	-3	no	10.259	10.252	EPSD	COSMIC	8.808	Down-regulation
CMGC_CDK_CDK5_CDK5_ST	P04637	TP53	Q00535	CDK5	T155	P152H	152	Missense	distal	-3	no	10.259	10.237	EPSD	COSMIC	8.808	Down-regulation
CMGC_CDK_CDK5_CDK5_ST	P04637	TP53	Q00535	CDK5	T155	A159S	159	Missense	distal	4	no	10.259	10.321	EPSD	COSMIC	8.808	Up-regulation
CMGC_CDK_CDK5_CDK5_ST	P04637	TP53	Q00535	CDK5	T155	P153T	153	Missense	proximal	-2	no	10.259	10.120	EPSD	COSMIC	8.808	Down-regulation
CMGC_CDK_CDK5_CDK5_ST	P04637	TP53	Q00535	CDK5	T155	A159T	159	Missense	distal	4	no	10.259	10.319	EPSD	COSMIC	8.808	Up-regulation
CMGC_CDK_CDK5_CDK5_ST	P04637	TP53	Q00535	CDK5	T155	P153L	153	Missense	proximal	-2	no	10.259	9.844	EPSD	COSMIC	8.808	Down-regulation
CMGC_CDK_CDK5_CDK5_ST	P04637	TP53	Q00535	CDK5	T155	S149P	149	Missense	distal	-6	no	10.259	10.220	EPSD	COSMIC	8.808	Down-regulation
CMGC_CDK_CDK5_CDK5_ST	P04637	TP53	Q00535	CDK5	T155	P152K	152	Missense	distal	-3	no	10.259	10.288	EPSD	COSMIC	8.808	Up-regulation
CMGC_CDK_CDK5_CDK5_ST	P04637	TP53	Q00535	CDK5	T155	P153S	153	Missense	proximal	-2	no	10.259	10.160	EPSD	COSMIC	8.808	Down-regulation
CMGC_CDK_CDK5_CDK5_ST	P04637	TP53	Q00535	CDK5	T155	G154C	154	Missense	proximal	-1	no	10.259	10.257	EPSD	COSMIC	8.808	Down-regulation
CMGC_CDK_CDK5_CDK5_ST	P04637	TP53	Q00535	CDK5	T155	S149F	149	Missense	distal	-6	no	10.259	10.086	EPSD	COSMIC	8.808	Down-regulation
CMGC_CDK_CDK5_CDK5_ST	P04637	TP53	Q00535	CDK5	T155	M160K	160	Missense	distal	5	no	10.259	10.601	EPSD	COSMIC	8.808	Up-regulation
CMGC_CDK_CDK5_CDK5_ST	P04637	TP53	Q00535	CDK5	T155	M160L	160	Missense	distal	5	no	10.259	10.278	EPSD	COSMIC	8.808	Up-regulation
CMGC_CDK_CDK5_CDK5_ST	P04637	TP53	Q00535	CDK5	T155	I162V	162	Missense	distal	7	no	10.259	10.263	EPSD	COSMIC	8.808	Up-regulation
CMGC_CDK_CDK5_CDK5_ST	P04637	TP53	Q00535	CDK5	T155	V157I	157	Missense	proximal	2	no	10.259	10.202	EPSD	COSMIC	8.808	Down-regulation
CMGC_CDK_CDK5_CDK5_ST	P04637	TP53	Q00535	CDK5	T155	A161G	161	Missense	distal	6	no	10.259	10.261	EPSD	COSMIC	8.808	Up-regulation
CMGC_CDK_CDK5_CDK5_ST	P04637	TP53	Q00535	CDK5	T155	D148V	148	Missense	distal	-7	no	10.259	10.285	EPSD	COSMIC	8.808	Up-regulation
CMGC_CDK_CDK5_CDK5_ST	P04637	TP53	Q00535	CDK5	T155	I162M	162	Missense	distal	7	no	10.259	10.251	EPSD	COSMIC	8.808	Down-regulation
CMGC_CDK_CDK5_CDK5_ST	P04637	TP53	Q00535	CDK5	T155	S149Y	149	Missense	distal	-6	no	10.259	10.126	EPSD	COSMIC	8.808	Down-regulation
CMGC_CDK_CDK5_CDK5_ST	P04637	TP53	Q00535	CDK5	T155	M160V	160	Missense	distal	5	no	10.259	10.426	EPSD	COSMIC	8.808	Up-regulation
CMGC_CDK_CDK5_CDK5_ST	P04637	TP53	Q00535	CDK5	T155	A159D	159	Missense	distal	4	no	10.259	10.260	EPSD	COSMIC;GDSC;CCLE	8.808	Up-regulation
CMGC_CDK_CDK5_CDK5_ST	P04637	TP53	Q00535	CDK5	T155	T150I	150	Missense	distal	-5	no	10.259	10.152	EPSD	COSMIC	8.808	Down-regulation
CMGC_CDK_CDK5_CDK5_ST	P04637	TP53	Q00535	CDK5	T155	S149T	149	Missense	distal	-6	no	10.259	10.231	EPSD	COSMIC	8.808	Down-regulation
CMGC_CDK_CDK5_CDK5_ST	P04637	TP53	Q00535	CDK5	T155	R156S	156	Missense	proximal	1	no	10.259	7.305	EPSD	COSMIC	8.808	Loss
CMGC_CDK_CDK5_CDK5_ST	P04637	TP53	Q00535	CDK5	T155	D148E	148	Missense	distal	-7	no	10.259	10.257	EPSD	COSMIC	8.808	Down-regulation
CMGC_CDK_CDK5_CDK5_ST	P04637	TP53	Q00535	CDK5	T155	T155A	155	Missense	central	0	yes	10.259	0.000	EPSD	COSMIC	8.808	Loss
CMGC_CDK_CDK5_CDK5_ST	P04637	TP53	Q00535	CDK5	T155	G154I	154	Missense	proximal	-1	no	10.259	10.261	EPSD	COSMIC	8.808	Up-regulation
CMGC_CDK_CDK5_CDK5_ST	P04637	TP53	Q00535	CDK5	T155	D148G	148	Missense	distal	-7	no	10.259	10.251	EPSD	COSMIC	8.808	Down-regulation
CMGC_CDK_CDK5_CDK5_ST	P04637	TP53	Q00535	CDK5	T155	T150K	150	Missense	distal	-5	no	10.259	10.400	EPSD	COSMIC	8.808	Up-regulation
CMGC_CDK_CDK5_CDK5_ST	P04637	TP53	Q00535	CDK5	T155	P153H	153	Missense	proximal	-2	no	10.259	9.943	EPSD	COSMIC	8.808	Down-regulation
CMGC_CDK_CDK5_CDK5_ST	P04637	TP53	Q00535	CDK5	T155	A161F	161	Missense	distal	6	no	10.259	10.251	EPSD	COSMIC	8.808	Down-regulation
CMGC_CDK_CDK5_CDK5_ST	P04637	TP53	Q00535	CDK5	T155	V157E	157	Missense	proximal	2	no	10.259	10.171	EPSD	COSMIC	8.808	Down-regulation
CMGC_CDK_CDK5_CDK5_ST	P04637	TP53	Q00535	CDK5	T155	D148H	148	Missense	distal	-7	no	10.259	10.272	EPSD	COSMIC	8.808	Up-regulation
CMGC_CDK_CDK5_CDK5_ST	P04637	TP53	Q00535	CDK5	T155	M160T	160	Missense	distal	5	no	10.259	10.463	EPSD	COSMIC	8.808	Up-regulation
CMGC_CDK_CDK5_CDK5_ST	P04637	TP53	Q00535	CDK5	T155	P153A	153	Missense	proximal	-2	no	10.259	9.882	EPSD	COSMIC	8.808	Down-regulation
CMGC_CDK_CDK5_CDK5_ST	P04637	TP53	Q00535	CDK5	T155	T150R	150	Missense	distal	-5	no	10.259	10.365	EPSD	COSMIC	8.808	Up-regulation
CMGC_CDK_CDK5_CDK5_ST	P04637	TP53	Q00535	CDK5	T155	T155L	155	Missense	central	0	yes	10.259	0.000	EPSD	COSMIC	8.808	Loss
CMGC_CDK_CDK5_CDK5_ST	P04637	TP53	Q00535	CDK5	T155	G154A	154	Missense	proximal	-1	no	10.259	10.258	EPSD	COSMIC	8.808	Down-regulation
CMGC_CDK_CDK5_CDK5_ST	P04637	TP53	Q00535	CDK5	T155	T150A	150	Missense	distal	-5	no	10.259	10.103	EPSD	COSMIC	8.808	Down-regulation
CMGC_CDK_CDK5_CDK5_ST	P04637	TP53	Q00535	CDK5	T155	R158F	158	Missense	distal	3	no	10.259	7.663	EPSD	COSMIC	8.808	Loss
CMGC_CDK_CDK5_CDK5_ST	P04637	TP53	Q00535	CDK5	T155	P153F	153	Missense	proximal	-2	no	10.259	9.601	EPSD	COSMIC	8.808	Down-regulation
CMGC_CDK_CDK5_CDK5_ST	P04637	TP53	Q00535	CDK5	T155	D148Y	148	Missense	distal	-7	no	10.259	10.237	EPSD	COSMIC	8.808	Down-regulation
CMGC_CDK_CDK5_CDK5_ST	P04637	TP53	Q00535	CDK5	T155	A161N	161	Missense	distal	6	no	10.259	10.266	EPSD	COSMIC	8.808	Up-regulation
CMGC_CDK_CDK5_CDK5_ST	P04637	TP53	Q00535	CDK5	T155	G154R	154	Missense	proximal	-1	no	10.259	10.263	EPSD	COSMIC	8.808	Up-regulation
CMGC_CDK_CDK5_CDK5_ST	P04637	TP53	Q00535	CDK5	S314	S315P	315	Missense	proximal	1	no	5.887	17.788	EPSD	COSMIC	8.808	Gain
CMGC_CDK_CDK5_CDK5_ST	P04637	TP53	Q00535	CDK5	S315	N310T	310	Missense	distal	-5	no	18.385	18.451	EPSD	COSMIC	8.808	Up-regulation
CMGC_CDK_CDK5_CDK5_ST	P04637	TP53	Q00535	CDK5	S315	Q317R	317	Missense	proximal	2	no	18.385	18.524	EPSD	COSMIC	8.808	Up-regulation
CMGC_CDK_CDK5_CDK5_ST	P04637	TP53	Q00535	CDK5	S315	P309S	309	Missense	distal	-6	no	18.385	18.424	EPSD	COSMIC;GDSC;CCLE	8.808	Up-regulation
CMGC_CDK_CDK5_CDK5_ST	P04637	TP53	Q00535	CDK5	S315	K319E	319	Missense	distal	4	no	18.385	18.268	EPSD	COSMIC	8.808	Down-regulation
CMGC_CDK_CDK5_CDK5_ST	P04637	TP53	Q00535	CDK5	S315	P322L	322	Missense	distal	7	no	18.385	18.373	EPSD	COSMIC	8.808	Down-regulation
CMGC_CDK_CDK5_CDK5_ST	P04637	TP53	Q00535	CDK5	S315	K320N	320	Missense	distal	5	no	18.385	18.182	EPSD	COSMIC;GDSC;CCLE	8.808	Down-regulation
CMGC_CDK_CDK5_CDK5_ST	P04637	TP53	Q00535	CDK5	S315	N310L	310	Missense	distal	-5	no	18.385	18.256	EPSD	COSMIC	8.808	Down-regulation
CMGC_CDK_CDK5_CDK5_ST	P04637	TP53	Q00535	CDK5	S315	T312S	312	Missense	distal	-3	no	18.385	18.386	EPSD	COSMIC	8.808	Up-regulation
CMGC_CDK_CDK5_CDK5_ST	P04637	TP53	Q00535	CDK5	S315	N311Y	311	Missense	distal	-4	no	18.385	17.917	EPSD	COSMIC	8.808	Down-regulation
CMGC_CDK_CDK5_CDK5_ST	P04637	TP53	Q00535	CDK5	S315	P322R	322	Missense	distal	7	no	18.385	18.387	EPSD	COSMIC	8.808	Up-regulation
CMGC_CDK_CDK5_CDK5_ST	P04637	TP53	Q00535	CDK5	S315	N311K	311	Missense	distal	-4	no	18.385	18.772	EPSD	COSMIC	8.808	Up-regulation
CMGC_CDK_CDK5_CDK5_ST	P04637	TP53	Q00535	CDK5	S315	Q317K	317	Missense	proximal	2	no	18.385	18.573	EPSD	COSMIC	8.808	Up-regulation
CMGC_CDK_CDK5_CDK5_ST	P04637	TP53	Q00535	CDK5	S315	S315P	315	Missense	central	0	yes	18.385	0.000	EPSD	COSMIC	8.808	Loss
CMGC_CDK_CDK5_CDK5_ST	P04637	TP53	Q00535	CDK5	S315	N310H	310	Missense	distal	-5	no	18.385	18.384	EPSD	COSMIC	8.808	Down-regulation
CMGC_CDK_CDK5_CDK5_ST	P04637	TP53	Q00535	CDK5	S315	S314C	314	Missense	proximal	-1	no	18.385	18.378	EPSD	COSMIC	8.808	Down-regulation
CMGC_CDK_CDK5_CDK5_ST	P04637	TP53	Q00535	CDK5	S315	P318A	318	Missense	distal	3	no	18.385	18.140	EPSD	COSMIC	8.808	Down-regulation
CMGC_CDK_CDK5_CDK5_ST	P04637	TP53	Q00535	CDK5	S315	P316L	316	Missense	proximal	1	no	18.385	6.435	EPSD	COSMIC	8.808	Loss
CMGC_CDK_CDK5_CDK5_ST	P04637	TP53	Q00535	CDK5	S315	L308M	308	Missense	distal	-7	no	18.385	18.369	EPSD	COSMIC	8.808	Down-regulation
CMGC_CDK_CDK5_CDK5_ST	P04637	TP53	Q00535	CDK5	S315	S313C	313	Missense	proximal	-2	no	18.385	17.912	EPSD	COSMIC	8.808	Down-regulation
CMGC_CDK_CDK5_CDK5_ST	P04637	TP53	Q00535	CDK5	S315	N311H	311	Missense	distal	-4	no	18.385	18.216	EPSD	COSMIC	8.808	Down-regulation
CMGC_CDK_CDK5_CDK5_ST	P04637	TP53	Q00535	CDK5	S315	L308V	308	Missense	distal	-7	no	18.385	18.423	EPSD	COSMIC	8.808	Up-regulation
CMGC_CDK_CDK5_CDK5_ST	P04637	TP53	Q00535	CDK5	S315	S314F	314	Missense	proximal	-1	no	18.385	18.376	EPSD	COSMIC	8.808	Down-regulation
CMGC_CDK_CDK5_CDK5_ST	P04637	TP53	Q00535	CDK5	S315	K319R	319	Missense	distal	4	no	18.385	18.337	EPSD	COSMIC	8.808	Down-regulation
CMGC_CDK_CDK5_CDK5_ST	P04637	TP53	Q00535	CDK5	S315	T312A	312	Missense	distal	-3	no	18.385	18.339	EPSD	COSMIC	8.808	Down-regulation
CMGC_CDK_CDK5_CDK5_ST	P04637	TP53	Q00535	CDK5	S315	N310D	310	Missense	distal	-5	no	18.385	18.311	EPSD	COSMIC	8.808	Down-regulation
CMGC_CDK_CDK5_CDK5_ST	P04637	TP53	Q00535	CDK5	S315	N311D	311	Missense	distal	-4	no	18.385	18.221	EPSD	COSMIC	8.808	Down-regulation
CMGC_CDK_CDK5_CDK5_ST	P04637	TP53	Q00535	CDK5	S315	P309R	309	Missense	distal	-6	no	18.385	18.430	EPSD	COSMIC	8.808	Up-regulation
CMGC_CDK_CDK5_CDK5_ST	P04637	TP53	Q00535	CDK5	S315	S313N	313	Missense	proximal	-2	no	18.385	18.271	EPSD	COSMIC	8.808	Down-regulation
CMGC_CDK_CDK5_CDK5_ST	P04637	TP53	Q00535	CDK5	S315	Q317P	317	Missense	proximal	2	no	18.385	18.442	EPSD	COSMIC	8.808	Up-regulation
CMGC_CDK_CDK5_CDK5_ST	P04637	TP53	Q00535	CDK5	S315	P316S	316	Missense	proximal	1	no	18.385	6.484	EPSD	COSMIC	8.808	Loss
CMGC_CDK_CDK5_CDK5_ST	P04637	TP53	Q00535	CDK5	S362	S367F	367	Missense	distal	5	no	9.264	9.025	EPSD	COSMIC	8.808	Down-regulation
CMGC_CDK_CDK5_CDK5_ST	P04637	TP53	Q00535	CDK5	S362	G361E	361	Missense	proximal	-1	no	9.264	9.265	EPSD	COSMIC	8.808	Up-regulation
CMGC_CDK_CDK5_CDK5_ST	P04637	TP53	Q00535	CDK5	S362	E358V	358	Missense	distal	-4	no	9.264	9.410	EPSD	COSMIC	8.808	Up-regulation
CMGC_CDK_CDK5_CDK5_ST	P04637	TP53	Q00535	CDK5	S362	P359S	359	Missense	distal	-3	no	9.264	9.259	EPSD	COSMIC	8.808	Down-regulation
CMGC_CDK_CDK5_CDK5_ST	P04637	TP53	Q00535	CDK5	S362	A364D	364	Missense	proximal	2	no	9.264	9.253	EPSD	COSMIC	8.808	Down-regulation
CMGC_CDK_CDK5_CDK5_ST	P04637	TP53	Q00535	CDK5	S362	H365Y	365	Missense	distal	3	no	9.264	8.097	EPSD	COSMIC	8.808	Loss
CMGC_CDK_CDK5_CDK5_ST	P04637	TP53	Q00535	CDK5	S362	G360A	360	Missense	proximal	-2	no	9.264	9.351	EPSD	COSMIC	8.808	Up-regulation
CMGC_CDK_CDK5_CDK5_ST	P04637	TP53	Q00535	CDK5	S362	A364T	364	Missense	proximal	2	no	9.264	9.383	EPSD	COSMIC	8.808	Up-regulation
CMGC_CDK_CDK5_CDK5_ST	P04637	TP53	Q00535	CDK5	S362	G356W	356	Missense	distal	-6	no	9.264	9.260	EPSD	COSMIC	8.808	Down-regulation
CMGC_CDK_CDK5_CDK5_ST	P04637	TP53	Q00535	CDK5	S362	S366A	366	Missense	distal	4	no	9.264	9.202	EPSD	COSMIC	8.808	Down-regulation
CMGC_CDK_CDK5_CDK5_ST	P04637	TP53	Q00535	CDK5	S362	E358Q	358	Missense	distal	-4	no	9.264	9.421	EPSD	COSMIC	8.808	Up-regulation
CMGC_CDK_CDK5_CDK5_ST	P04637	TP53	Q00535	CDK5	S362	G361R	361	Missense	proximal	-1	no	9.264	9.269	EPSD	COSMIC	8.808	Up-regulation
CMGC_CDK_CDK5_CDK5_ST	P04637	TP53	Q00535	CDK5	S362	E358K	358	Missense	distal	-4	no	9.264	9.767	EPSD	COSMIC	8.808	Up-regulation
CMGC_CDK_CDK5_CDK5_ST	P04637	TP53	Q00535	CDK5	S376	K370N	370	Missense	distal	-6	no	10.348	10.247	EPSD	COSMIC	8.808	Down-regulation
CMGC_CDK_CDK5_CDK5_ST	P04637	TP53	Q00535	CDK5	S376	L383F	383	Missense	distal	7	no	10.348	10.343	EPSD	COSMIC	8.808	Down-regulation
CMGC_CDK_CDK5_CDK5_ST	P04637	TP53	Q00535	CDK5	S376	R379H	379	Missense	distal	3	no	10.348	9.329	EPSD	COSMIC	8.808	Down-regulation
CMGC_CDK_CDK5_CDK5_ST	P04637	TP53	Q00535	CDK5	S376	H380Y	380	Missense	distal	4	no	10.348	10.285	EPSD	COSMIC	8.808	Down-regulation
CMGC_CDK_CDK5_CDK5_ST	P04637	TP53	Q00535	CDK5	S376	T377I	377	Missense	proximal	1	no	10.348	3.749	EPSD	COSMIC	8.808	Loss
CMGC_CDK_CDK5_CDK5_ST	P04637	TP53	Q00535	CDK5	S376	S378F	378	Missense	proximal	2	no	10.348	10.138	EPSD	COSMIC	8.808	Down-regulation
CMGC_CDK_CDK5_CDK5_ST	P04637	TP53	Q00535	CDK5	S376	K370Q	370	Missense	distal	-6	no	10.348	10.254	EPSD	COSMIC	8.808	Down-regulation
CMGC_CDK_CDK5_CDK5_ST	P04637	TP53	Q00535	CDK5	S376	K381N	381	Missense	distal	5	no	10.348	10.146	EPSD	COSMIC	8.808	Down-regulation
CMGC_CDK_CDK5_CDK5_ST	P04637	TP53	Q00535	CDK5	S376	R379P	379	Missense	distal	3	no	10.348	8.949	EPSD	COSMIC	8.808	Down-regulation
CMGC_CDK_CDK5_CDK5_ST	P04637	TP53	Q00535	CDK5	S376	K373R	373	Missense	distal	-3	no	10.348	10.328	EPSD	COSMIC	8.808	Down-regulation
CMGC_CDK_CDK5_CDK5_ST	P04637	TP53	Q00535	CDK5	S376	S376F	376	Missense	central	0	yes	10.348	0.000	EPSD	COSMIC	8.808	Loss
CMGC_CDK_CDK5_CDK5_ST	P04637	TP53	Q00535	CDK5	S376	G374S	374	Missense	proximal	-2	no	10.348	10.714	EPSD	COSMIC	8.808	Up-regulation
CMGC_CDK_CDK5_CDK5_ST	P04637	TP53	Q00535	CDK5	S376	S376A	376	Missense	central	0	yes	10.348	0.000	EPSD	COSMIC	8.808	Loss
CMGC_CDK_CDK5_CDK5_ST	P04637	TP53	Q00535	CDK5	S376	S371P	371	Missense	distal	-5	no	10.348	10.326	EPSD	COSMIC	8.808	Down-regulation
CMGC_CDK_CDK5_CDK5_ST	P04637	TP53	Q00535	CDK5	S378	L383F	383	Missense	distal	5	no	11.670	11.616	EPSD	COSMIC	8.808	Down-regulation
CMGC_CDK_CDK5_CDK5_ST	P04637	TP53	Q00535	CDK5	S378	R379H	379	Missense	proximal	1	no	11.670	2.105	EPSD	COSMIC	8.808	Loss
CMGC_CDK_CDK5_CDK5_ST	P04637	TP53	Q00535	CDK5	S378	S376T	376	Missense	proximal	-2	no	11.670	11.630	EPSD	COSMIC	8.808	Down-regulation
CMGC_CDK_CDK5_CDK5_ST	P04637	TP53	Q00535	CDK5	S378	H380Y	380	Missense	proximal	2	no	11.670	11.535	EPSD	COSMIC	8.808	Down-regulation
CMGC_CDK_CDK5_CDK5_ST	P04637	TP53	Q00535	CDK5	S378	T377I	377	Missense	proximal	-1	no	11.670	11.668	EPSD	COSMIC	8.808	Down-regulation
CMGC_CDK_CDK5_CDK5_ST	P04637	TP53	Q00535	CDK5	S378	S378F	378	Missense	central	0	yes	11.670	0.000	EPSD	COSMIC	8.808	Loss
CMGC_CDK_CDK5_CDK5_ST	P04637	TP53	Q00535	CDK5	S378	K381N	381	Missense	distal	3	no	11.670	9.737	EPSD	COSMIC	8.808	Down-regulation
CMGC_CDK_CDK5_CDK5_ST	P04637	TP53	Q00535	CDK5	S378	R379P	379	Missense	proximal	1	no	11.670	20.617	EPSD	COSMIC	8.808	Up-regulation
CMGC_CDK_CDK5_CDK5_ST	P04637	TP53	Q00535	CDK5	S378	M384I	384	Missense	distal	6	no	11.670	11.681	EPSD	COSMIC	8.808	Up-regulation
CMGC_CDK_CDK5_CDK5_ST	P04637	TP53	Q00535	CDK5	S378	K373R	373	Missense	distal	-5	no	11.670	11.636	EPSD	COSMIC	8.808	Down-regulation
CMGC_CDK_CDK5_CDK5_ST	P04637	TP53	Q00535	CDK5	S378	S376F	376	Missense	proximal	-2	no	11.670	11.111	EPSD	COSMIC	8.808	Down-regulation
CMGC_CDK_CDK5_CDK5_ST	P04637	TP53	Q00535	CDK5	S378	G374S	374	Missense	distal	-4	no	11.670	12.512	EPSD	COSMIC	8.808	Up-regulation
CMGC_CDK_CDK5_CDK5_ST	P04637	TP53	Q00535	CDK5	S378	S376A	376	Missense	proximal	-2	no	11.670	11.392	EPSD	COSMIC	8.808	Down-regulation
CMGC_CDK_CDK5_CDK5_ST	P04637	TP53	Q00535	CDK5	S378	S371P	371	Missense	distal	-7	no	11.670	11.666	EPSD	COSMIC	8.808	Down-regulation
CMGC_CDK_CDK5_CDK5_ST	Q99490	AGAP2	Q00535	CDK5	S140	G134V	134	Missense	distal	-6	no	9.318	9.368	EPSD	COSMIC;CCLE	8.808	Up-regulation
CMGC_CDK_CDK5_CDK5_ST	Q99490	AGAP2	Q00535	CDK5	S267	S273F	273	Missense	distal	6	no	20.291	20.271	EPSD	COSMIC	8.808	Down-regulation
CMGC_CDK_CDK5_CDK5_ST	Q99490	AGAP2	Q00535	CDK5	S267	P268A	268	Missense	proximal	1	no	20.291	9.265	EPSD	COSMIC	8.808	Down-regulation
CMGC_CDK_CDK5_CDK5_ST	Q99490	AGAP2	Q00535	CDK5	S523	R525Q	525	Missense	proximal	2	no	18.242	18.103	EPSD	COSMIC	8.808	Down-regulation
CMGC_CDK_CDK5_CDK5_ST	Q99490	AGAP2	Q00535	CDK5	S584	S585P	585	Missense	proximal	1	no	6.025	17.926	EPSD	COSMIC	8.808	Gain
CMGC_CDK_CDK5_CDK5_ST	Q99490	AGAP2	Q00535	CDK5	S585	S585P	585	Missense	central	0	yes	18.493	0.000	EPSD	COSMIC	8.808	Loss
CMGC_CDK_CDK5_CDK5_ST	Q99490	AGAP2	Q00535	CDK5	S585	A591E	591	Missense	distal	6	no	18.493	18.495	EPSD	COSMIC	8.808	Up-regulation
CMGC_CDK_CDK5_CDK5_ST	Q99490	AGAP2	Q00535	CDK5	T593	A591E	591	Missense	proximal	-2	no	17.193	17.129	EPSD	COSMIC	8.808	Down-regulation
CMGC_CDK_CDK5_CDK5_ST	Q99490	AGAP2	Q00535	CDK5	S615	P613Q	613	Missense	proximal	-2	no	18.478	18.286	EPSD	COSMIC	8.808	Down-regulation
CMGC_CDK_CDK5_CDK5_ST	Q99490	AGAP2	Q00535	CDK5	S615	Y608H	608	Missense	distal	-7	no	18.478	18.512	EPSD	COSMIC	8.808	Up-regulation
CMGC_CDK_CDK5_CDK5_ST	Q99490	AGAP2	Q00535	CDK5	S615	S609F	609	Missense	distal	-6	no	18.478	18.304	EPSD	COSMIC;GDSC;CCLE	8.808	Down-regulation
CMGC_CDK_CDK5_CDK5_ST	Q99490	AGAP2	Q00535	CDK5	S615	E622K	622	Missense	distal	7	no	18.478	18.494	EPSD	COSMIC	8.808	Up-regulation
CMGC_CDK_CDK5_CDK5_ST	Q99490	AGAP2	Q00535	CDK5	S615	Y608C	608	Missense	distal	-7	no	18.478	18.471	EPSD	COSMIC;GDSC;CCLE	8.808	Down-regulation
CMGC_CDK_CDK5_CDK5_ST	Q99490	AGAP2	Q00535	CDK5	T635	G637W	637	Missense	proximal	2	no	16.338	16.319	EPSD	COSMIC	8.808	Down-regulation
CMGC_CDK_CDK5_CDK5_ST	Q99490	AGAP2	Q00535	CDK5	T635	A642T	642	Missense	distal	7	no	16.338	16.347	EPSD	COSMIC	8.808	Up-regulation
CMGC_CDK_CDK5_CDK5_ST	Q99490	AGAP2	Q00535	CDK5	T635	R641Q	641	Missense	distal	6	no	16.338	16.327	EPSD	COSMIC	8.808	Down-regulation
CMGC_CDK_CDK5_CDK5_ST	Q99490	AGAP2	Q00535	CDK5	T812	D816Y	816	Missense	distal	4	no	16.822	16.797	EPSD	COSMIC	8.808	Down-regulation
CMGC_CDK_CDK5_CDK5_ST	Q99490	AGAP2	Q00535	CDK5	S818	D816Y	816	Missense	proximal	-2	no	17.622	17.427	EPSD	COSMIC	8.808	Down-regulation
CMGC_CDK_CDK5_CDK5_ST	Q99490	AGAP2	Q00535	CDK5	S818	L820P	820	Missense	proximal	2	no	17.622	17.787	EPSD	COSMIC	8.808	Up-regulation
CMGC_CDK_CDK5_CDK5_ST	Q99490	AGAP2	Q00535	CDK5	S827	R834K	834	Missense	distal	7	no	18.771	18.776	EPSD	COSMIC	8.808	Up-regulation
CMGC_CDK_CDK5_CDK5_ST	Q99490	AGAP2	Q00535	CDK5	S827	L820P	820	Missense	distal	-7	no	18.771	18.823	EPSD	COSMIC	8.808	Up-regulation
CMGC_CDK_CDK5_CDK5_ST	Q99490	AGAP2	Q00535	CDK5	S827	M829T	829	Missense	proximal	2	no	18.771	18.969	EPSD	COSMIC	8.808	Up-regulation
CMGC_CDK_CDK5_CDK5_ST	O15516	CLOCK	Q00535	CDK5	S427	S433P	433	Missense	distal	6	no	17.450	17.449	EPSD	COSMIC	8.808	Down-regulation
CMGC_CDK_CDK5_CDK5_ST	O15516	CLOCK	Q00535	CDK5	S427	T429A	429	Missense	proximal	2	no	17.450	17.331	EPSD	COSMIC	8.808	Down-regulation
CMGC_CDK_CDK5_CDK5_ST	O15516	CLOCK	Q00535	CDK5	S427	R423G	423	Missense	distal	-4	no	17.450	17.070	EPSD	COSMIC	8.808	Down-regulation
CMGC_CDK_CDK5_CDK5_ST	O15516	CLOCK	Q00535	CDK5	T429	S433P	433	Missense	distal	4	no	16.361	16.359	EPSD	COSMIC	8.808	Down-regulation
CMGC_CDK_CDK5_CDK5_ST	O15516	CLOCK	Q00535	CDK5	T429	T429A	429	Missense	central	0	yes	16.361	0.000	EPSD	COSMIC	8.808	Loss
CMGC_CDK_CDK5_CDK5_ST	O15516	CLOCK	Q00535	CDK5	T429	R435Q	435	Missense	distal	6	no	16.361	16.350	EPSD	COSMIC;GDSC;CCLE	8.808	Down-regulation
CMGC_CDK_CDK5_CDK5_ST	O15516	CLOCK	Q00535	CDK5	T429	R423G	423	Missense	distal	-6	no	16.361	16.260	EPSD	COSMIC	8.808	Down-regulation
CMGC_CDK_CDK5_CDK5_ST	O15516	CLOCK	Q00535	CDK5	S437	S433P	433	Missense	distal	-4	no	9.628	9.281	EPSD	COSMIC	8.808	Down-regulation
CMGC_CDK_CDK5_CDK5_ST	O15516	CLOCK	Q00535	CDK5	S437	R435Q	435	Missense	proximal	-2	no	9.628	9.491	EPSD	COSMIC;GDSC;CCLE	8.808	Down-regulation
CMGC_CDK_CDK5_CDK5_ST	O15516	CLOCK	Q00535	CDK5	S450	P456S	456	Missense	distal	6	no	8.859	8.860	EPSD	COSMIC	8.808	Up-regulation
CMGC_CDK_CDK5_CDK5_ST	O15516	CLOCK	Q00535	CDK5	S450	T457M	457	Missense	distal	7	no	8.859	8.846	EPSD	COSMIC	8.808	Down-regulation
CMGC_CDK_CDK5_CDK5_ST	O15516	CLOCK	Q00535	CDK5	T451	P456S	456	Missense	distal	5	no	19.355	19.367	PhosphoSitePlus;EPSD	COSMIC	8.808	Up-regulation
CMGC_CDK_CDK5_CDK5_ST	O15516	CLOCK	Q00535	CDK5	T451	T457M	457	Missense	distal	6	no	19.355	19.338	PhosphoSitePlus;EPSD	COSMIC	8.808	Down-regulation
CMGC_CDK_CDK5_CDK5_ST	O15516	CLOCK	Q00535	CDK5	T461	S460N	460	Missense	proximal	-1	no	18.112	18.110	EPSD;PhosphoSitePlus	COSMIC	8.808	Down-regulation
CMGC_CDK_CDK5_CDK5_ST	O15516	CLOCK	Q00535	CDK5	T461	P456S	456	Missense	distal	-5	no	18.112	18.135	EPSD;PhosphoSitePlus	COSMIC	8.808	Up-regulation
CMGC_CDK_CDK5_CDK5_ST	O15516	CLOCK	Q00535	CDK5	T461	T457M	457	Missense	distal	-4	no	18.112	17.545	EPSD;PhosphoSitePlus	COSMIC	8.808	Down-regulation
CMGC_CDK_CDK5_CDK5_ST	O15516	CLOCK	Q00535	CDK5	T461	R464K	464	Missense	distal	3	no	18.112	18.432	EPSD;PhosphoSitePlus	COSMIC	8.808	Up-regulation
CMGC_CDK_CDK5_CDK5_ST	Q14194	CRMP1	Q00535	CDK5	S14	D15N	15	Missense	proximal	1	no	7.913	9.380	EPSD	COSMIC	8.808	Gain
CMGC_CDK_CDK5_CDK5_ST	Q14194	CRMP1	Q00535	CDK5	S304	A298V	298	Missense	distal	-6	no	17.133	17.202	EPSD	COSMIC	8.808	Up-regulation
CMGC_CDK_CDK5_CDK5_ST	Q14194	CRMP1	Q00535	CDK5	S304	A298T	298	Missense	distal	-6	no	17.133	17.219	EPSD	COSMIC	8.808	Up-regulation
CMGC_CDK_CDK5_CDK5_ST	Q14194	CRMP1	Q00535	CDK5	S304	A300T	300	Missense	distal	-4	no	17.133	17.532	EPSD	COSMIC;CCLE	8.808	Up-regulation
CMGC_CDK_CDK5_CDK5_ST	Q14194	CRMP1	Q00535	CDK5	S308	P314T	314	Missense	distal	6	no	18.518	18.519	EPSD	COSMIC;CCLE	8.808	Up-regulation
CMGC_CDK_CDK5_CDK5_ST	Q14194	CRMP1	Q00535	CDK5	S442	V445A	445	Missense	distal	3	no	16.904	16.652	EPSD	COSMIC	8.808	Down-regulation
CMGC_CDK_CDK5_CDK5_ST	Q14194	CRMP1	Q00535	CDK5	S442	E435K	435	Missense	distal	-7	no	16.904	16.967	EPSD	COSMIC	8.808	Up-regulation
CMGC_CDK_CDK5_CDK5_ST	Q14194	CRMP1	Q00535	CDK5	S448	G441D	441	Missense	distal	-7	no	9.741	9.750	EPSD	COSMIC	8.808	Up-regulation
CMGC_CDK_CDK5_CDK5_ST	Q14194	CRMP1	Q00535	CDK5	S448	V453I	453	Missense	distal	5	no	9.741	9.689	EPSD	COSMIC	8.808	Down-regulation
CMGC_CDK_CDK5_CDK5_ST	Q14194	CRMP1	Q00535	CDK5	S448	V445A	445	Missense	distal	-3	no	9.741	9.703	EPSD	COSMIC	8.808	Down-regulation
CMGC_CDK_CDK5_CDK5_ST	Q14194	CRMP1	Q00535	CDK5	S448	G450C	450	Missense	proximal	2	no	9.741	9.647	EPSD	COSMIC	8.808	Down-regulation
CMGC_CDK_CDK5_CDK5_ST	Q14194	CRMP1	Q00535	CDK5	T509	A508G	508	Missense	proximal	-1	no	15.893	15.894	PhosphoSitePlus;EPSD	COSMIC	8.808	Up-regulation
CMGC_CDK_CDK5_CDK5_ST	Q14194	CRMP1	Q00535	CDK5	T509	P515L	515	Missense	distal	6	no	15.893	15.879	PhosphoSitePlus;EPSD	COSMIC	8.808	Down-regulation
CMGC_CDK_CDK5_CDK5_ST	Q14194	CRMP1	Q00535	CDK5	T509	P510H	510	Missense	proximal	1	no	15.893	-2.619	PhosphoSitePlus;EPSD	COSMIC	8.808	Loss
CMGC_CDK_CDK5_CDK5_ST	Q14194	CRMP1	Q00535	CDK5	T509	E505K	505	Missense	distal	-4	no	15.893	16.396	PhosphoSitePlus;EPSD	COSMIC	8.808	Up-regulation
CMGC_CDK_CDK5_CDK5_ST	Q14194	CRMP1	Q00535	CDK5	T509	E505D	505	Missense	distal	-4	no	15.893	15.845	PhosphoSitePlus;EPSD	COSMIC	8.808	Down-regulation
CMGC_CDK_CDK5_CDK5_ST	Q14194	CRMP1	Q00535	CDK5	T509	A516V	516	Missense	distal	7	no	15.893	15.901	PhosphoSitePlus;EPSD	COSMIC	8.808	Up-regulation
CMGC_CDK_CDK5_CDK5_ST	Q14194	CRMP1	Q00535	CDK5	T514	A508G	508	Missense	distal	-6	no	16.996	17.015	EPSD	COSMIC	8.808	Up-regulation
CMGC_CDK_CDK5_CDK5_ST	Q14194	CRMP1	Q00535	CDK5	T514	S521Y	521	Missense	distal	7	no	16.996	16.982	EPSD	COSMIC	8.808	Down-regulation
CMGC_CDK_CDK5_CDK5_ST	Q14194	CRMP1	Q00535	CDK5	T514	P515L	515	Missense	proximal	1	no	16.996	5.046	EPSD	COSMIC	8.808	Loss
CMGC_CDK_CDK5_CDK5_ST	Q14194	CRMP1	Q00535	CDK5	T514	P510H	510	Missense	distal	-4	no	16.996	16.661	EPSD	COSMIC	8.808	Down-regulation
CMGC_CDK_CDK5_CDK5_ST	Q14194	CRMP1	Q00535	CDK5	T514	A516V	516	Missense	proximal	2	no	16.996	17.077	EPSD	COSMIC	8.808	Up-regulation
CMGC_CDK_CDK5_CDK5_ST	Q14194	CRMP1	Q00535	CDK5	S522	S522L	522	Missense	central	0	yes	20.485	0.000	EPSD;PhosphoSitePlus	COSMIC	8.808	Loss
CMGC_CDK_CDK5_CDK5_ST	Q14194	CRMP1	Q00535	CDK5	S522	S521Y	521	Missense	proximal	-1	no	20.485	20.478	EPSD;PhosphoSitePlus	COSMIC	8.808	Down-regulation
CMGC_CDK_CDK5_CDK5_ST	Q14194	CRMP1	Q00535	CDK5	S522	P515L	515	Missense	distal	-7	no	20.485	20.433	EPSD;PhosphoSitePlus	COSMIC	8.808	Down-regulation
CMGC_CDK_CDK5_CDK5_ST	Q14194	CRMP1	Q00535	CDK5	S522	Q527H	527	Missense	distal	5	no	20.485	20.507	EPSD;PhosphoSitePlus	COSMIC;CCLE	8.808	Up-regulation
CMGC_CDK_CDK5_CDK5_ST	Q14194	CRMP1	Q00535	CDK5	S522	P528T	528	Missense	distal	6	no	20.485	20.486	EPSD;PhosphoSitePlus	COSMIC	8.808	Up-regulation
CMGC_CDK_CDK5_CDK5_ST	Q14194	CRMP1	Q00535	CDK5	S522	P528L	528	Missense	distal	6	no	20.485	20.471	EPSD;PhosphoSitePlus	COSMIC	8.808	Down-regulation
CMGC_CDK_CDK5_CDK5_ST	Q14194	CRMP1	Q00535	CDK5	S522	A516V	516	Missense	distal	-6	no	20.485	20.554	EPSD;PhosphoSitePlus	COSMIC	8.808	Up-regulation
CMGC_CDK_CDK5_CDK5_ST	P35612	ADD2	Q00535	CDK5	S11	P13S	13	Missense	proximal	2	no	19.042	19.024	EPSD	COSMIC	8.808	Down-regulation
CMGC_CDK_CDK5_CDK5_ST	P35612	ADD2	Q00535	CDK5	S11	P7L	7	Missense	distal	-4	no	19.042	18.569	EPSD	COSMIC	8.808	Down-regulation
CMGC_CDK_CDK5_CDK5_ST	P35612	ADD2	Q00535	CDK5	S11	P15L	15	Missense	distal	4	no	19.042	18.961	EPSD	COSMIC	8.808	Down-regulation
CMGC_CDK_CDK5_CDK5_ST	P35612	ADD2	Q00535	CDK5	S11	Q18R	18	Missense	distal	7	no	19.042	19.048	EPSD	COSMIC	8.808	Up-regulation
CMGC_CDK_CDK5_CDK5_ST	P35612	ADD2	Q00535	CDK5	S11	P12S	12	Missense	proximal	1	no	19.042	7.141	EPSD	COSMIC	8.808	Loss
CMGC_CDK_CDK5_CDK5_ST	P35612	ADD2	Q00535	CDK5	S11	S11L	11	Missense	central	0	yes	19.042	0.000	EPSD	COSMIC	8.808	Loss
CMGC_CDK_CDK5_CDK5_ST	P35612	ADD2	Q00535	CDK5	S11	P7T	7	Missense	distal	-4	no	19.042	18.886	EPSD	COSMIC	8.808	Down-regulation
CMGC_CDK_CDK5_CDK5_ST	P35612	ADD2	Q00535	CDK5	S11	Q16R	16	Missense	distal	5	no	19.042	19.167	EPSD	COSMIC	8.808	Up-regulation
CMGC_CDK_CDK5_CDK5_ST	P35612	ADD2	Q00535	CDK5	S60	R53W	53	Missense	distal	-7	no	15.928	15.879	EPSD	COSMIC	8.808	Down-regulation
CMGC_CDK_CDK5_CDK5_ST	P35612	ADD2	Q00535	CDK5	S60	R53Q	53	Missense	distal	-7	no	15.928	15.908	EPSD	COSMIC	8.808	Down-regulation
CMGC_CDK_CDK5_CDK5_ST	P35612	ADD2	Q00535	CDK5	T436	E429K	429	Missense	distal	-7	no	17.896	17.959	EPSD	COSMIC	8.808	Up-regulation
CMGC_CDK_CDK5_CDK5_ST	P35612	ADD2	Q00535	CDK5	T436	R432G	432	Missense	distal	-4	no	17.896	17.516	EPSD	COSMIC	8.808	Down-regulation
CMGC_CDK_CDK5_CDK5_ST	P35612	ADD2	Q00535	CDK5	S455	Q450H	450	Missense	distal	-5	no	17.512	17.500	EPSD	COSMIC	8.808	Down-regulation
CMGC_CDK_CDK5_CDK5_ST	P35612	ADD2	Q00535	CDK5	S455	S455N	455	Missense	central	0	yes	17.512	0.000	EPSD	COSMIC	8.808	Loss
CMGC_CDK_CDK5_CDK5_ST	P35612	ADD2	Q00535	CDK5	S530	S528T	528	Missense	proximal	-2	no	17.904	17.863	EPSD	COSMIC	8.808	Down-regulation
CMGC_CDK_CDK5_CDK5_ST	P35612	ADD2	Q00535	CDK5	S592	G591A	591	Missense	proximal	-1	no	19.175	19.174	EPSD	COSMIC	8.808	Down-regulation
CMGC_CDK_CDK5_CDK5_ST	P35612	ADD2	Q00535	CDK5	S592	A594E	594	Missense	proximal	2	no	19.175	19.168	EPSD	COSMIC	8.808	Down-regulation
CMGC_CDK_CDK5_CDK5_ST	P35612	ADD2	Q00535	CDK5	S600	A594E	594	Missense	distal	-6	no	17.846	17.873	EPSD	COSMIC	8.808	Up-regulation
CMGC_CDK_CDK5_CDK5_ST	P35612	ADD2	Q00535	CDK5	S667	L662F	662	Missense	distal	-5	no	9.069	8.960	EPSD	COSMIC	8.808	Down-regulation
CMGC_CDK_CDK5_CDK5_ST	P35612	ADD2	Q00535	CDK5	S667	S663N	663	Missense	distal	-4	no	9.069	8.557	EPSD	COSMIC	8.808	Loss
CMGC_CDK_CDK5_CDK5_ST	P35612	ADD2	Q00535	CDK5	S693	P694L	694	Missense	proximal	1	no	18.849	6.899	EPSD	COSMIC	8.808	Loss
CMGC_CDK_CDK5_CDK5_ST	P35612	ADD2	Q00535	CDK5	S693	S689G	689	Missense	distal	-4	no	18.849	18.008	EPSD	COSMIC	8.808	Down-regulation
CMGC_CDK_CDK5_CDK5_ST	P35612	ADD2	Q00535	CDK5	S693	P698L	698	Missense	distal	5	no	18.849	18.676	EPSD	COSMIC	8.808	Down-regulation
CMGC_CDK_CDK5_CDK5_ST	P35612	ADD2	Q00535	CDK5	S697	P694L	694	Missense	distal	-3	no	19.283	19.222	EPSD	COSMIC	8.808	Down-regulation
CMGC_CDK_CDK5_CDK5_ST	P35612	ADD2	Q00535	CDK5	S697	P702S	702	Missense	distal	5	no	19.283	19.295	EPSD	COSMIC	8.808	Up-regulation
CMGC_CDK_CDK5_CDK5_ST	P35612	ADD2	Q00535	CDK5	S697	P698L	698	Missense	proximal	1	no	19.283	7.333	EPSD	COSMIC	8.808	Loss
CMGC_CDK_CDK5_CDK5_ST	P35612	ADD2	Q00535	CDK5	S701	P694L	694	Missense	distal	-7	no	19.958	19.906	PhosphoSitePlus;EPSD	COSMIC	8.808	Down-regulation
CMGC_CDK_CDK5_CDK5_ST	P35612	ADD2	Q00535	CDK5	S701	P702S	702	Missense	proximal	1	no	19.958	8.057	PhosphoSitePlus;EPSD	COSMIC	8.808	Loss
CMGC_CDK_CDK5_CDK5_ST	P35612	ADD2	Q00535	CDK5	S701	P698L	698	Missense	distal	-3	no	19.958	19.897	PhosphoSitePlus;EPSD	COSMIC	8.808	Down-regulation
CMGC_CDK_CDK5_CDK5_ST	P35612	ADD2	Q00535	CDK5	T711	P712S	712	Missense	proximal	1	no	17.101	5.200	EPSD	COSMIC	8.808	Loss
CMGC_CDK_CDK5_CDK5_ST	P35612	ADD2	Q00535	CDK5	T711	F709Y	709	Missense	proximal	-2	no	17.101	17.231	EPSD	COSMIC	8.808	Up-regulation
CMGC_CDK_CDK5_CDK5_ST	P35612	ADD2	Q00535	CDK5	T711	S718R	718	Missense	distal	7	no	17.101	17.103	EPSD	COSMIC;GDSC;CCLE	8.808	Up-regulation
CMGC_CDK_CDK5_CDK5_ST	P35612	ADD2	Q00535	CDK5	T711	F709L	709	Missense	proximal	-2	no	17.101	17.344	EPSD	COSMIC	8.808	Up-regulation
CMGC_CDK_CDK5_CDK5_ST	O00429	DNM1L	Q00535	CDK5	S126	S119L	119	Missense	distal	-7	no	17.427	17.371	EPSD	COSMIC	8.808	Down-regulation
CMGC_CDK_CDK5_CDK5_ST	O00429	DNM1L	Q00535	CDK5	S126	K133N	133	Missense	distal	7	no	17.427	17.416	EPSD	COSMIC	8.808	Down-regulation
CMGC_CDK_CDK5_CDK5_ST	O00429	DNM1L	Q00535	CDK5	S126	G124E	124	Missense	proximal	-2	no	17.427	17.450	EPSD	COSMIC	8.808	Up-regulation
CMGC_CDK_CDK5_CDK5_ST	O00429	DNM1L	Q00535	CDK5	S126	G124R	124	Missense	proximal	-2	no	17.427	17.837	EPSD	COSMIC	8.808	Up-regulation
CMGC_CDK_CDK5_CDK5_ST	O00429	DNM1L	Q00535	CDK5	S126	G120C	120	Missense	distal	-6	no	17.427	17.376	EPSD	COSMIC	8.808	Down-regulation
CMGC_CDK_CDK5_CDK5_ST	O00429	DNM1L	Q00535	CDK5	S136	K133N	133	Missense	distal	-3	no	17.605	17.553	EPSD	COSMIC	8.808	Down-regulation
CMGC_CDK_CDK5_CDK5_ST	O00429	DNM1L	Q00535	CDK5	S529	D531H	531	Missense	proximal	2	no	11.576	11.666	EPSD	COSMIC	8.808	Up-regulation
CMGC_CDK_CDK5_CDK5_ST	O00429	DNM1L	Q00535	CDK5	S529	E523D	523	Missense	distal	-6	no	11.576	11.566	EPSD	COSMIC	8.808	Down-regulation
CMGC_CDK_CDK5_CDK5_ST	O00429	DNM1L	Q00535	CDK5	S529	S529L	529	Missense	central	0	yes	11.576	0.000	EPSD	COSMIC	8.808	Loss
CMGC_CDK_CDK5_CDK5_ST	O00429	DNM1L	Q00535	CDK5	S529	S526L	526	Missense	distal	-3	no	11.576	11.520	EPSD	COSMIC	8.808	Down-regulation
CMGC_CDK_CDK5_CDK5_ST	O00429	DNM1L	Q00535	CDK5	S548	A543S	543	Missense	distal	-5	no	17.721	17.902	EPSD	COSMIC	8.808	Up-regulation
CMGC_CDK_CDK5_CDK5_ST	O00429	DNM1L	Q00535	CDK5	S548	Q545K	545	Missense	distal	-3	no	17.721	17.767	EPSD	COSMIC	8.808	Up-regulation
CMGC_CDK_CDK5_CDK5_ST	O00429	DNM1L	Q00535	CDK5	S616	P611L	611	Missense	distal	-5	no	19.887	19.690	PhosphoSitePlus	COSMIC	8.808	Down-regulation
CMGC_CDK_CDK5_CDK5_ST	O00429	DNM1L	Q00535	CDK5	S616	A622D	622	Missense	distal	6	no	19.887	19.888	PhosphoSitePlus	COSMIC	8.808	Up-regulation
CMGC_CDK_CDK5_CDK5_ST	Q8IV63	VRK3	Q00535	CDK5	S71	L74S	74	Missense	distal	3	no	17.408	18.460	EPSD	COSMIC	8.808	Up-regulation
CMGC_CDK_CDK5_CDK5_ST	Q8IV63	VRK3	Q00535	CDK5	S71	V69L	69	Missense	proximal	-2	no	17.408	17.174	EPSD	COSMIC	8.808	Down-regulation
CMGC_CDK_CDK5_CDK5_ST	Q8IV63	VRK3	Q00535	CDK5	S71	S75F	75	Missense	distal	4	no	17.408	17.296	EPSD	COSMIC	8.808	Down-regulation
CMGC_CDK_CDK5_CDK5_ST	Q8IV63	VRK3	Q00535	CDK5	S98	G99R	99	Missense	proximal	1	no	-2.547	9.922	EPSD	COSMIC;CCLE	8.808	Gain
CMGC_CDK_CDK5_CDK5_ST	Q8IV63	VRK3	Q00535	CDK5	S100	G99R	99	Missense	proximal	-1	no	9.393	9.398	EPSD	COSMIC;CCLE	8.808	Up-regulation
CMGC_CDK_CDK5_CDK5_ST	Q8IV63	VRK3	Q00535	CDK5	T104	G99R	99	Missense	distal	-5	no	18.410	18.662	EPSD	COSMIC;CCLE	8.808	Up-regulation
CMGC_CDK_CDK5_CDK5_ST	Q8IV63	VRK3	Q00535	CDK5	S122	C128G	128	Missense	distal	6	no	19.149	19.155	EPSD	COSMIC	8.808	Up-regulation
CMGC_CDK_CDK5_CDK5_ST	Q8IV63	VRK3	Q00535	CDK5	S122	C128S	128	Missense	distal	6	no	19.149	19.165	EPSD	COSMIC	8.808	Up-regulation
CMGC_CDK_CDK5_CDK5_ST	Q8IV63	VRK3	Q00535	CDK5	S122	S127R	127	Missense	distal	5	no	19.149	19.212	EPSD	COSMIC;GDSC;CCLE	8.808	Up-regulation
CMGC_CDK_CDK5_CDK5_ST	Q8IV63	VRK3	Q00535	CDK5	S129	C128G	128	Missense	proximal	-1	no	19.829	19.831	EPSD	COSMIC	8.808	Up-regulation
CMGC_CDK_CDK5_CDK5_ST	Q8IV63	VRK3	Q00535	CDK5	S129	C128S	128	Missense	proximal	-1	no	19.829	19.836	EPSD	COSMIC	8.808	Up-regulation
CMGC_CDK_CDK5_CDK5_ST	Q8IV63	VRK3	Q00535	CDK5	S129	S127R	127	Missense	proximal	-2	no	19.829	19.873	EPSD	COSMIC;GDSC;CCLE	8.808	Up-regulation
CMGC_CDK_CDK5_CDK5_ST	Q8IV63	VRK3	Q00535	CDK5	S129	K132N	132	Missense	distal	3	no	19.829	17.896	EPSD	COSMIC	8.808	Down-regulation
CMGC_CDK_CDK5_CDK5_ST	Q8IV63	VRK3	Q00535	CDK5	S136	R142Q	142	Missense	distal	6	no	18.166	18.155	EPSD	COSMIC;GDSC;CCLE	8.808	Down-regulation
CMGC_CDK_CDK5_CDK5_ST	Q8IV63	VRK3	Q00535	CDK5	S136	K132N	132	Missense	distal	-4	no	18.166	17.778	EPSD	COSMIC	8.808	Down-regulation
CMGC_CDK_CDK5_CDK5_ST	Q8IV63	VRK3	Q00535	CDK5	S136	T139M	139	Missense	distal	3	no	18.166	16.668	EPSD	COSMIC	8.808	Down-regulation
CMGC_CDK_CDK5_CDK5_ST	Q8IV63	VRK3	Q00535	CDK5	S136	Q138H	138	Missense	proximal	2	no	18.166	18.191	EPSD	COSMIC	8.808	Up-regulation
CMGC_CDK_CDK5_CDK5_ST	Q8IV63	VRK3	Q00535	CDK5	S143	E150K	150	Missense	distal	7	no	9.357	9.373	EPSD	COSMIC	8.808	Up-regulation
CMGC_CDK_CDK5_CDK5_ST	Q8IV63	VRK3	Q00535	CDK5	S143	R144Q	144	Missense	proximal	1	no	9.357	9.328	EPSD	COSMIC	8.808	Down-regulation
CMGC_CDK_CDK5_CDK5_ST	Q8IV63	VRK3	Q00535	CDK5	S143	R142Q	142	Missense	proximal	-1	no	9.357	9.355	EPSD	COSMIC;GDSC;CCLE	8.808	Down-regulation
CMGC_CDK_CDK5_CDK5_ST	Q8IV63	VRK3	Q00535	CDK5	S143	V145M	145	Missense	proximal	2	no	9.357	9.197	EPSD	COSMIC	8.808	Down-regulation
CMGC_CDK_CDK5_CDK5_ST	Q8IV63	VRK3	Q00535	CDK5	S143	T139M	139	Missense	distal	-4	no	9.357	8.790	EPSD	COSMIC	8.808	Loss
CMGC_CDK_CDK5_CDK5_ST	Q8IV63	VRK3	Q00535	CDK5	S143	Q138H	138	Missense	distal	-5	no	9.357	9.345	EPSD	COSMIC	8.808	Down-regulation
CMGC_CDK_CDK5_CDK5_ST	Q8IV63	VRK3	Q00535	CDK5	S268	A269P	269	Missense	proximal	1	no	6.749	17.776	EPSD	COSMIC	8.808	Gain
CMGC_CDK_CDK5_CDK5_ST	Q8IV63	VRK3	Q00535	CDK5	S273	A269P	269	Missense	distal	-4	no	18.924	19.479	EPSD	COSMIC	8.808	Up-regulation
CMGC_CDK_CDK5_CDK5_ST	Q8IV63	VRK3	Q00535	CDK5	S348	R347G	347	Missense	proximal	-1	no	17.815	17.811	EPSD	COSMIC	8.808	Down-regulation
CMGC_CDK_CDK5_CDK5_ST	Q16665	HIF1A	Q00535	CDK5	S14	R18G	18	Missense	distal	4	no	9.177	9.109	EPSD	COSMIC	8.808	Down-regulation
CMGC_CDK_CDK5_CDK5_ST	Q16665	HIF1A	Q00535	CDK5	S14	R18H	18	Missense	distal	4	no	9.177	9.137	EPSD	COSMIC	8.808	Down-regulation
CMGC_CDK_CDK5_CDK5_ST	Q16665	HIF1A	Q00535	CDK5	S14	S15R	15	Missense	proximal	1	no	9.177	12.131	EPSD	COSMIC	8.808	Up-regulation
CMGC_CDK_CDK5_CDK5_ST	Q16665	HIF1A	Q00535	CDK5	S14	R17H	17	Missense	distal	3	no	9.177	8.158	EPSD	COSMIC	8.808	Loss
CMGC_CDK_CDK5_CDK5_ST	Q16665	HIF1A	Q00535	CDK5	S14	S14R	14	Missense	central	0	yes	9.177	0.000	EPSD	COSMIC	8.808	Loss
CMGC_CDK_CDK5_CDK5_ST	Q16665	HIF1A	Q00535	CDK5	S14	E20K	20	Missense	distal	6	no	9.177	9.195	EPSD	COSMIC	8.808	Up-regulation
CMGC_CDK_CDK5_CDK5_ST	Q16665	HIF1A	Q00535	CDK5	S28	R30W	30	Missense	proximal	2	no	9.582	9.390	EPSD	COSMIC	8.808	Down-regulation
CMGC_CDK_CDK5_CDK5_ST	Q16665	HIF1A	Q00535	CDK5	S28	D24Y	24	Missense	distal	-4	no	9.582	9.278	EPSD	COSMIC	8.808	Down-regulation
CMGC_CDK_CDK5_CDK5_ST	Q16665	HIF1A	Q00535	CDK5	S28	R30Q	30	Missense	proximal	2	no	9.582	9.443	EPSD	COSMIC	8.808	Down-regulation
CMGC_CDK_CDK5_CDK5_ST	Q16665	HIF1A	Q00535	CDK5	S28	R29W	29	Missense	proximal	1	no	9.582	-0.276	EPSD	COSMIC	8.808	Loss
CMGC_CDK_CDK5_CDK5_ST	Q16665	HIF1A	Q00535	CDK5	S28	S22Y	22	Missense	distal	-6	no	9.582	9.449	EPSD	COSMIC	8.808	Down-regulation
CMGC_CDK_CDK5_CDK5_ST	Q16665	HIF1A	Q00535	CDK5	S451	P452A	452	Missense	proximal	1	no	18.046	7.019	EPSD	COSMIC	8.808	Loss
CMGC_CDK_CDK5_CDK5_ST	Q16665	HIF1A	Q00535	CDK5	S451	A456T	456	Missense	distal	5	no	18.046	18.179	EPSD	COSMIC	8.808	Up-regulation
CMGC_CDK_CDK5_CDK5_ST	Q16665	HIF1A	Q00535	CDK5	S451	A456S	456	Missense	distal	5	no	18.046	18.180	EPSD	COSMIC	8.808	Up-regulation
CMGC_CDK_CDK5_CDK5_ST	Q16665	HIF1A	Q00535	CDK5	S451	N447K	447	Missense	distal	-4	no	18.046	18.433	EPSD	COSMIC	8.808	Up-regulation
CMGC_CDK_CDK5_CDK5_ST	Q16665	HIF1A	Q00535	CDK5	T458	P452A	452	Missense	distal	-6	no	17.591	17.516	EPSD	COSMIC	8.808	Down-regulation
CMGC_CDK_CDK5_CDK5_ST	Q16665	HIF1A	Q00535	CDK5	T458	A456T	456	Missense	proximal	-2	no	17.591	17.829	EPSD	COSMIC	8.808	Up-regulation
CMGC_CDK_CDK5_CDK5_ST	Q16665	HIF1A	Q00535	CDK5	T458	A456S	456	Missense	proximal	-2	no	17.591	17.869	EPSD	COSMIC	8.808	Up-regulation
CMGC_CDK_CDK5_CDK5_ST	Q16665	HIF1A	Q00535	CDK5	S500	Q497H	497	Missense	distal	-3	no	17.237	17.232	EPSD	COSMIC	8.808	Down-regulation
CMGC_CDK_CDK5_CDK5_ST	Q16665	HIF1A	Q00535	CDK5	S500	R507K	507	Missense	distal	7	no	17.237	17.242	EPSD	COSMIC	8.808	Up-regulation
CMGC_CDK_CDK5_CDK5_ST	Q16665	HIF1A	Q00535	CDK5	S500	P501L	501	Missense	proximal	1	no	17.237	5.288	EPSD	COSMIC	8.808	Loss
CMGC_CDK_CDK5_CDK5_ST	Q16665	HIF1A	Q00535	CDK5	S500	Q495K	495	Missense	distal	-5	no	17.237	17.433	EPSD	COSMIC	8.808	Up-regulation
CMGC_CDK_CDK5_CDK5_ST	Q16665	HIF1A	Q00535	CDK5	S500	Q495R	495	Missense	distal	-5	no	17.237	17.398	EPSD	COSMIC	8.808	Up-regulation
CMGC_CDK_CDK5_CDK5_ST	Q16665	HIF1A	Q00535	CDK5	S500	D503N	503	Missense	distal	3	no	17.237	17.656	EPSD	COSMIC	8.808	Up-regulation
CMGC_CDK_CDK5_CDK5_ST	Q16665	HIF1A	Q00535	CDK5	S510	R507K	507	Missense	distal	-3	no	18.561	18.581	EPSD	COSMIC	8.808	Up-regulation
CMGC_CDK_CDK5_CDK5_ST	Q16665	HIF1A	Q00535	CDK5	S510	E512V	512	Missense	proximal	2	no	18.561	18.650	EPSD	COSMIC;GDSC	8.808	Up-regulation
CMGC_CDK_CDK5_CDK5_ST	Q16665	HIF1A	Q00535	CDK5	S510	P516H	516	Missense	distal	6	no	18.561	18.558	EPSD	COSMIC	8.808	Down-regulation
CMGC_CDK_CDK5_CDK5_ST	Q16665	HIF1A	Q00535	CDK5	S510	S517T	517	Missense	distal	7	no	18.561	18.559	EPSD	COSMIC	8.808	Down-regulation
CMGC_CDK_CDK5_CDK5_ST	Q16665	HIF1A	Q00535	CDK5	S510	D503N	503	Missense	distal	-7	no	18.561	18.579	EPSD	COSMIC	8.808	Up-regulation
CMGC_CDK_CDK5_CDK5_ST	Q16665	HIF1A	Q00535	CDK5	S515	E512V	512	Missense	distal	-3	no	17.825	17.855	EPSD	COSMIC;GDSC	8.808	Up-regulation
CMGC_CDK_CDK5_CDK5_ST	Q16665	HIF1A	Q00535	CDK5	S515	P516H	516	Missense	proximal	1	no	17.825	-0.687	EPSD	COSMIC	8.808	Loss
CMGC_CDK_CDK5_CDK5_ST	Q16665	HIF1A	Q00535	CDK5	S515	S517T	517	Missense	proximal	2	no	17.825	17.850	EPSD	COSMIC	8.808	Up-regulation
CMGC_CDK_CDK5_CDK5_ST	Q16665	HIF1A	Q00535	CDK5	S515	Y522H	522	Missense	distal	7	no	17.825	17.834	EPSD	COSMIC	8.808	Up-regulation
CMGC_CDK_CDK5_CDK5_ST	Q16665	HIF1A	Q00535	CDK5	S589	Q596E	596	Missense	distal	7	no	18.794	18.789	EPSD	COSMIC	8.808	Down-regulation
CMGC_CDK_CDK5_CDK5_ST	Q16665	HIF1A	Q00535	CDK5	S589	A588T	588	Missense	proximal	-1	no	18.794	18.798	EPSD	COSMIC	8.808	Up-regulation
CMGC_CDK_CDK5_CDK5_ST	Q16665	HIF1A	Q00535	CDK5	S589	A588P	588	Missense	proximal	-1	no	18.794	18.798	EPSD	COSMIC	8.808	Up-regulation
CMGC_CDK_CDK5_CDK5_ST	Q16665	HIF1A	Q00535	CDK5	S589	P582S	582	Missense	distal	-7	no	18.794	18.798	EPSD	COSMIC	8.808	Up-regulation
CMGC_CDK_CDK5_CDK5_ST	Q16665	HIF1A	Q00535	CDK5	S589	A593T	593	Missense	distal	4	no	18.794	18.853	EPSD	COSMIC	8.808	Up-regulation
CMGC_CDK_CDK5_CDK5_ST	Q16665	HIF1A	Q00535	CDK5	S589	E584Q	584	Missense	distal	-5	no	18.794	18.888	EPSD	COSMIC	8.808	Up-regulation
CMGC_CDK_CDK5_CDK5_ST	Q16665	HIF1A	Q00535	CDK5	S589	E584D	584	Missense	distal	-5	no	18.794	18.803	EPSD	COSMIC	8.808	Up-regulation
CMGC_CDK_CDK5_CDK5_ST	Q16665	HIF1A	Q00535	CDK5	S641	I635F	635	Missense	distal	-6	no	17.186	17.085	EPSD	COSMIC	8.808	Down-regulation
CMGC_CDK_CDK5_CDK5_ST	Q16665	HIF1A	Q00535	CDK5	S641	A640P	640	Missense	proximal	-1	no	17.186	17.190	EPSD	COSMIC;GDSC	8.808	Up-regulation
CMGC_CDK_CDK5_CDK5_ST	Q16665	HIF1A	Q00535	CDK5	S641	P642S	642	Missense	proximal	1	no	17.186	5.285	EPSD	COSMIC	8.808	Loss
CMGC_CDK_CDK5_CDK5_ST	Q16665	HIF1A	Q00535	CDK5	S641	K636N	636	Missense	distal	-5	no	17.186	16.979	EPSD	COSMIC	8.808	Down-regulation
CMGC_CDK_CDK5_CDK5_ST	Q16665	HIF1A	Q00535	CDK5	S643	A640P	640	Missense	distal	-3	no	17.383	17.435	EPSD	COSMIC;GDSC	8.808	Up-regulation
CMGC_CDK_CDK5_CDK5_ST	Q16665	HIF1A	Q00535	CDK5	S643	P642S	642	Missense	proximal	-1	no	17.383	17.384	EPSD	COSMIC	8.808	Up-regulation
CMGC_CDK_CDK5_CDK5_ST	Q16665	HIF1A	Q00535	CDK5	S643	K636N	636	Missense	distal	-7	no	17.383	17.340	EPSD	COSMIC	8.808	Down-regulation
CMGC_CDK_CDK5_CDK5_ST	Q16665	HIF1A	Q00535	CDK5	S668	R671K	671	Missense	distal	3	no	19.370	19.690	EPSD	COSMIC	8.808	Up-regulation
CMGC_CDK_CDK5_CDK5_ST	Q16665	HIF1A	Q00535	CDK5	S668	T666S	666	Missense	proximal	-2	no	19.370	19.411	EPSD	COSMIC	8.808	Up-regulation
CMGC_CDK_CDK5_CDK5_ST	Q16665	HIF1A	Q00535	CDK5	S668	A672V	672	Missense	distal	4	no	19.370	19.413	EPSD	COSMIC	8.808	Up-regulation
CMGC_CDK_CDK5_CDK5_ST	Q16665	HIF1A	Q00535	CDK5	S687	E681D	681	Missense	distal	-6	no	18.717	18.708	PhosphoSitePlus	COSMIC	8.808	Down-regulation
CMGC_CDK_CDK5_CDK5_ST	Q16665	HIF1A	Q00535	CDK5	S687	P685Q	685	Missense	proximal	-2	no	18.717	18.526	PhosphoSitePlus	COSMIC	8.808	Down-regulation
CMGC_CDK_CDK5_CDK5_ST	Q16665	HIF1A	Q00535	CDK5	S687	V690M	690	Missense	distal	3	no	18.717	17.749	PhosphoSitePlus	COSMIC	8.808	Down-regulation
CMGC_CDK_CDK5_CDK5_ST	Q16665	HIF1A	Q00535	CDK5	S687	A694T	694	Missense	distal	7	no	18.717	18.726	PhosphoSitePlus	COSMIC;GDSC	8.808	Up-regulation
CMGC_CDK_CDK5_CDK5_ST	Q16665	HIF1A	Q00535	CDK5	S687	N689I	689	Missense	proximal	2	no	18.717	18.693	PhosphoSitePlus	COSMIC	8.808	Down-regulation
CMGC_CDK_CDK5_CDK5_ST	Q16665	HIF1A	Q00535	CDK5	S687	K682Q	682	Missense	distal	-5	no	18.717	18.522	PhosphoSitePlus	COSMIC	8.808	Down-regulation
CMGC_CDK_CDK5_CDK5_ST	Q16665	HIF1A	Q00535	CDK5	S687	S692F	692	Missense	distal	5	no	18.717	18.478	PhosphoSitePlus	COSMIC	8.808	Down-regulation
CMGC_CDK_CDK5_CDK5_ST	Q16665	HIF1A	Q00535	CDK5	S696	P702T	702	Missense	distal	6	no	9.640	9.641	EPSD	COSMIC;GDSC;CCLE	8.808	Up-regulation
CMGC_CDK_CDK5_CDK5_ST	Q16665	HIF1A	Q00535	CDK5	S696	V690M	690	Missense	distal	-6	no	9.640	9.536	EPSD	COSMIC	8.808	Down-regulation
CMGC_CDK_CDK5_CDK5_ST	Q16665	HIF1A	Q00535	CDK5	S696	P702L	702	Missense	distal	6	no	9.640	9.626	EPSD	COSMIC	8.808	Down-regulation
CMGC_CDK_CDK5_CDK5_ST	Q16665	HIF1A	Q00535	CDK5	S696	A694T	694	Missense	proximal	-2	no	9.640	9.878	EPSD	COSMIC;GDSC	8.808	Up-regulation
CMGC_CDK_CDK5_CDK5_ST	Q16665	HIF1A	Q00535	CDK5	S696	Q697E	697	Missense	proximal	1	no	9.640	-3.595	EPSD	COSMIC;GDSC;CCLE	8.808	Loss
CMGC_CDK_CDK5_CDK5_ST	Q16665	HIF1A	Q00535	CDK5	S696	N689I	689	Missense	distal	-7	no	9.640	9.632	EPSD	COSMIC	8.808	Down-regulation
CMGC_CDK_CDK5_CDK5_ST	Q16665	HIF1A	Q00535	CDK5	S696	S692F	692	Missense	distal	-4	no	9.640	8.479	EPSD	COSMIC	8.808	Loss
CMGC_CDK_CDK5_CDK5_ST	P07196	NEFL	Q00535	CDK5	T21	R16W	16	Missense	distal	-5	no	18.963	18.704	PhosphoSitePlus	COSMIC	8.808	Down-regulation
CMGC_CDK_CDK5_CDK5_ST	P07196	NEFL	Q00535	CDK5	T21	H25N	25	Missense	distal	4	no	18.963	18.955	PhosphoSitePlus	COSMIC	8.808	Down-regulation
CMGC_CDK_CDK5_CDK5_ST	P07196	NEFL	Q00535	CDK5	T21	S28N	28	Missense	distal	7	no	18.963	18.959	PhosphoSitePlus	COSMIC	8.808	Down-regulation
CMGC_CDK_CDK5_CDK5_ST	P07196	NEFL	Q00535	CDK5	T21	R16Q	16	Missense	distal	-5	no	18.963	18.802	PhosphoSitePlus	COSMIC	8.808	Down-regulation
CMGC_CDK_CDK5_CDK5_ST	P07196	NEFL	Q00535	CDK5	S27	S28N	28	Missense	proximal	1	no	7.632	10.294	EPSD	COSMIC	8.808	Gain
CMGC_CDK_CDK5_CDK5_ST	P07196	NEFL	Q00535	CDK5	S28	S31R	31	Missense	distal	3	no	7.621	9.039	EPSD	COSMIC	8.808	Gain
CMGC_CDK_CDK5_CDK5_ST	P07196	NEFL	Q00535	CDK5	S34	G32D	32	Missense	proximal	-2	no	8.684	8.814	EPSD	COSMIC	8.808	Gain
CMGC_CDK_CDK5_CDK5_ST	P07196	NEFL	Q00535	CDK5	T154	A149V	149	Missense	distal	-5	no	8.733	8.859	EPSD	COSMIC	8.808	Gain
CMGC_CDK_CDK5_CDK5_ST	P07196	NEFL	Q00535	CDK5	T154	A150V	150	Missense	distal	-4	no	8.733	9.153	EPSD	COSMIC	8.808	Gain
CMGC_CDK_CDK5_CDK5_ST	Q15717	ELAVL1	Q00535	CDK5	S146	G144C	144	Missense	proximal	-2	no	8.850	8.743	EPSD	COSMIC	8.808	Loss
CMGC_CDK_CDK5_CDK5_ST	Q15717	ELAVL1	Q00535	CDK5	S202	R206W	206	Missense	distal	4	no	19.114	19.042	PhosphoSitePlus	COSMIC	8.808	Down-regulation
CMGC_CDK_CDK5_CDK5_ST	Q15717	ELAVL1	Q00535	CDK5	S202	G208R	208	Missense	distal	6	no	19.114	19.131	PhosphoSitePlus	COSMIC	8.808	Up-regulation
CMGC_CDK_CDK5_CDK5_ST	Q15717	ELAVL1	Q00535	CDK5	S202	G208V	208	Missense	distal	6	no	19.114	19.121	PhosphoSitePlus	COSMIC	8.808	Up-regulation
CMGC_CDK_CDK5_CDK5_ST	Q15717	ELAVL1	Q00535	CDK5	S202	L195F	195	Missense	distal	-7	no	19.114	19.086	PhosphoSitePlus	COSMIC	8.808	Down-regulation
CMGC_CDK_CDK5_CDK5_ST	Q15717	ELAVL1	Q00535	CDK5	S221	V225I	225	Missense	distal	4	no	17.779	17.755	EPSD	COSMIC	8.808	Down-regulation
CMGC_CDK_CDK5_CDK5_ST	Q02750	MAP2K1	Q00535	CDK5	T55	Q58H	58	Missense	distal	3	no	8.124	8.907	EPSD	COSMIC	8.808	Gain
CMGC_CDK_CDK5_CDK5_ST	Q02750	MAP2K1	Q00535	CDK5	S231	Y229H	229	Missense	proximal	-2	no	19.243	19.455	EPSD	COSMIC	8.808	Up-regulation
CMGC_CDK_CDK5_CDK5_ST	Q02750	MAP2K1	Q00535	CDK5	T286	A283V	283	Missense	distal	-3	no	18.401	18.439	EPSD	COSMIC	8.808	Up-regulation
CMGC_CDK_CDK5_CDK5_ST	Q02750	MAP2K1	Q00535	CDK5	T286	R291K	291	Missense	distal	5	no	18.401	18.476	EPSD	COSMIC	8.808	Up-regulation
CMGC_CDK_CDK5_CDK5_ST	Q02750	MAP2K1	Q00535	CDK5	T292	P293S	293	Missense	proximal	1	no	19.368	7.467	PhosphoSitePlus	COSMIC	8.808	Loss
CMGC_CDK_CDK5_CDK5_ST	Q02750	MAP2K1	Q00535	CDK5	T292	R291K	291	Missense	proximal	-1	no	19.368	19.370	PhosphoSitePlus	COSMIC	8.808	Up-regulation
CMGC_CDK_CDK5_CDK5_ST	Q02750	MAP2K1	Q00535	CDK5	T386	P387S	387	Missense	proximal	1	no	18.515	6.614	EPSD	COSMIC	8.808	Loss
CMGC_CDK_CDK5_CDK5_ST	Q02750	MAP2K1	Q00535	CDK5	T386	A390T	390	Missense	distal	4	no	18.515	18.574	EPSD	COSMIC;GDSC	8.808	Up-regulation
CMGC_CDK_CDK5_CDK5_ST	Q02750	MAP2K1	Q00535	CDK5	T386	N382H	382	Missense	distal	-4	no	18.515	18.346	EPSD	COSMIC	8.808	Down-regulation
CMGC_CDK_CDK5_CDK5_ST	Q14814	MEF2D	Q00535	CDK5	S78	D83N	83	Missense	distal	5	no	8.836	8.905	EPSD	COSMIC	8.808	Up-regulation
CMGC_CDK_CDK5_CDK5_ST	Q14814	MEF2D	Q00535	CDK5	S78	A82T	82	Missense	distal	4	no	8.836	8.895	EPSD	COSMIC	8.808	Up-regulation
CMGC_CDK_CDK5_CDK5_ST	Q14814	MEF2D	Q00535	CDK5	S98	D102N	102	Missense	distal	4	no	16.728	16.758	EPSD	COSMIC	8.808	Up-regulation
CMGC_CDK_CDK5_CDK5_ST	Q14814	MEF2D	Q00535	CDK5	S98	E100G	100	Missense	proximal	2	no	16.728	16.756	EPSD	COSMIC	8.808	Up-regulation
CMGC_CDK_CDK5_CDK5_ST	Q14814	MEF2D	Q00535	CDK5	S98	G103R	103	Missense	distal	5	no	16.728	16.894	EPSD	COSMIC	8.808	Up-regulation
CMGC_CDK_CDK5_CDK5_ST	Q14814	MEF2D	Q00535	CDK5	S98	P101H	101	Missense	distal	3	no	16.728	17.107	EPSD	COSMIC	8.808	Up-regulation
CMGC_CDK_CDK5_CDK5_ST	Q14814	MEF2D	Q00535	CDK5	S98	D97Y	97	Missense	proximal	-1	no	16.728	16.726	EPSD	COSMIC	8.808	Down-regulation
CMGC_CDK_CDK5_CDK5_ST	Q14814	MEF2D	Q00535	CDK5	S110	S106P	106	Missense	distal	-4	no	16.893	16.547	EPSD	COSMIC	8.808	Down-regulation
CMGC_CDK_CDK5_CDK5_ST	Q14814	MEF2D	Q00535	CDK5	S110	G103R	103	Missense	distal	-7	no	16.893	16.945	EPSD	COSMIC	8.808	Up-regulation
CMGC_CDK_CDK5_CDK5_ST	Q14814	MEF2D	Q00535	CDK5	S180	R177W	177	Missense	distal	-3	no	17.294	17.241	EPSD	COSMIC	8.808	Down-regulation
CMGC_CDK_CDK5_CDK5_ST	Q14814	MEF2D	Q00535	CDK5	S180	L178M	178	Missense	proximal	-2	no	17.294	17.136	EPSD	COSMIC	8.808	Down-regulation
CMGC_CDK_CDK5_CDK5_ST	Q14814	MEF2D	Q00535	CDK5	S231	L235F	235	Missense	distal	4	no	17.677	17.648	EPSD	COSMIC	8.808	Down-regulation
CMGC_CDK_CDK5_CDK5_ST	Q14814	MEF2D	Q00535	CDK5	S231	P236H	236	Missense	distal	5	no	17.677	17.649	EPSD	COSMIC	8.808	Down-regulation
CMGC_CDK_CDK5_CDK5_ST	Q14814	MEF2D	Q00535	CDK5	S231	L234F	234	Missense	distal	3	no	17.677	17.551	EPSD	COSMIC	8.808	Down-regulation
CMGC_CDK_CDK5_CDK5_ST	Q14814	MEF2D	Q00535	CDK5	S251	S258R	258	Missense	distal	7	no	17.827	17.829	EPSD	COSMIC	8.808	Up-regulation
CMGC_CDK_CDK5_CDK5_ST	Q14814	MEF2D	Q00535	CDK5	S251	P254S	254	Missense	distal	3	no	17.827	17.807	EPSD	COSMIC	8.808	Down-regulation
CMGC_CDK_CDK5_CDK5_ST	Q14814	MEF2D	Q00535	CDK5	S444	P442L	442	Missense	proximal	-2	no	20.530	20.115	PhosphoSitePlus	COSMIC	8.808	Down-regulation
CMGC_CDK_CDK5_CDK5_ST	Q14814	MEF2D	Q00535	CDK5	S444	R449C	449	Missense	distal	5	no	20.530	20.274	PhosphoSitePlus	COSMIC	8.808	Down-regulation
CMGC_CDK_CDK5_CDK5_ST	Q14814	MEF2D	Q00535	CDK5	S444	R447H	447	Missense	distal	3	no	20.530	19.511	PhosphoSitePlus	COSMIC	8.808	Down-regulation
CMGC_CDK_CDK5_CDK5_ST	Q14814	MEF2D	Q00535	CDK5	S446	P442L	442	Missense	distal	-4	no	10.776	10.303	EPSD	COSMIC	8.808	Down-regulation
CMGC_CDK_CDK5_CDK5_ST	Q14814	MEF2D	Q00535	CDK5	S446	R449C	449	Missense	distal	3	no	10.776	8.480	EPSD	COSMIC	8.808	Loss
CMGC_CDK_CDK5_CDK5_ST	Q14814	MEF2D	Q00535	CDK5	S446	R447H	447	Missense	proximal	1	no	10.776	1.211	EPSD	COSMIC	8.808	Loss
CMGC_CDK_CDK5_CDK5_ST	Q14814	MEF2D	Q00535	CDK5	S450	P453S	453	Missense	distal	3	no	18.610	18.590	EPSD	COSMIC	8.808	Down-regulation
CMGC_CDK_CDK5_CDK5_ST	Q14814	MEF2D	Q00535	CDK5	S450	R449C	449	Missense	proximal	-1	no	18.610	18.603	EPSD	COSMIC	8.808	Down-regulation
CMGC_CDK_CDK5_CDK5_ST	Q14814	MEF2D	Q00535	CDK5	S450	R447H	447	Missense	distal	-3	no	18.610	18.578	EPSD	COSMIC	8.808	Down-regulation
CMGC_CDK_CDK5_CDK5_ST	Q14814	MEF2D	Q00535	CDK5	S472	G469E	469	Missense	distal	-3	no	16.962	16.965	EPSD	COSMIC	8.808	Up-regulation
CMGC_CDK_CDK5_CDK5_ST	Q14814	MEF2D	Q00535	CDK5	S472	P466L	466	Missense	distal	-6	no	16.962	16.879	EPSD	COSMIC	8.808	Down-regulation
CMGC_CDK_CDK5_CDK5_ST	Q14814	MEF2D	Q00535	CDK5	S472	P466A	466	Missense	distal	-6	no	16.962	16.887	EPSD	COSMIC	8.808	Down-regulation
CMGC_CDK_CDK5_CDK5_ST	Q14814	MEF2D	Q00535	CDK5	S472	P473A	473	Missense	proximal	1	no	16.962	5.936	EPSD	COSMIC	8.808	Loss
CMGC_CDK_CDK5_CDK5_ST	Q14814	MEF2D	Q00535	CDK5	S472	P466S	466	Missense	distal	-6	no	16.962	17.001	EPSD	COSMIC	8.808	Up-regulation
CMGC_CDK_CDK5_CDK5_ST	Q14814	MEF2D	Q00535	CDK5	S472	S477A	477	Missense	distal	5	no	16.962	16.828	EPSD	COSMIC	8.808	Down-regulation
CMGC_CDK_CDK5_CDK5_ST	Q14814	MEF2D	Q00535	CDK5	S472	G469C	469	Missense	distal	-3	no	16.962	16.939	EPSD	COSMIC;GDSC;CCLE	8.808	Down-regulation
CMGC_CDK_CDK5_CDK5_ST	Q14814	MEF2D	Q00535	CDK5	S508	V510L	510	Missense	proximal	2	no	9.177	9.043	EPSD	COSMIC	8.808	Down-regulation
CMGC_CDK_CDK5_CDK5_ST	Q14814	MEF2D	Q00535	CDK5	S508	R514L	514	Missense	distal	6	no	9.177	9.155	EPSD	COSMIC	8.808	Down-regulation
CMGC_CDK_CDK5_CDK5_ST	Q96KR7	PHACTR3	Q00535	CDK5	T45	P47T	47	Missense	proximal	2	no	15.997	16.004	EPSD	COSMIC	8.808	Up-regulation
CMGC_CDK_CDK5_CDK5_ST	Q96KR7	PHACTR3	Q00535	CDK5	T45	E51K	51	Missense	distal	6	no	15.997	16.015	EPSD	COSMIC	8.808	Up-regulation
CMGC_CDK_CDK5_CDK5_ST	Q96KR7	PHACTR3	Q00535	CDK5	T45	M42I	42	Missense	distal	-3	no	15.997	16.037	EPSD	COSMIC	8.808	Up-regulation
CMGC_CDK_CDK5_CDK5_ST	Q96KR7	PHACTR3	Q00535	CDK5	T45	P47L	47	Missense	proximal	2	no	15.997	15.831	EPSD	COSMIC	8.808	Down-regulation
CMGC_CDK_CDK5_CDK5_ST	Q96KR7	PHACTR3	Q00535	CDK5	T45	P47S	47	Missense	proximal	2	no	15.997	15.979	EPSD	COSMIC	8.808	Down-regulation
CMGC_CDK_CDK5_CDK5_ST	Q96KR7	PHACTR3	Q00535	CDK5	T45	T45M	45	Missense	central	0	yes	15.997	0.000	EPSD	COSMIC	8.808	Loss
CMGC_CDK_CDK5_CDK5_ST	Q96KR7	PHACTR3	Q00535	CDK5	T45	P50T	50	Missense	distal	5	no	15.997	16.009	EPSD	COSMIC	8.808	Up-regulation
CMGC_CDK_CDK5_CDK5_ST	Q96KR7	PHACTR3	Q00535	CDK5	S156	S156Y	156	Missense	central	0	yes	17.190	0.000	EPSD	COSMIC	8.808	Loss
CMGC_CDK_CDK5_CDK5_ST	Q96KR7	PHACTR3	Q00535	CDK5	S156	D163N	163	Missense	distal	7	no	17.190	17.194	EPSD	COSMIC	8.808	Up-regulation
CMGC_CDK_CDK5_CDK5_ST	Q96KR7	PHACTR3	Q00535	CDK5	S156	A152T	152	Missense	distal	-4	no	17.190	17.590	EPSD	COSMIC	8.808	Up-regulation
CMGC_CDK_CDK5_CDK5_ST	Q96KR7	PHACTR3	Q00535	CDK5	S156	G161V	161	Missense	distal	5	no	17.190	17.256	EPSD	COSMIC	8.808	Up-regulation
CMGC_CDK_CDK5_CDK5_ST	Q96KR7	PHACTR3	Q00535	CDK5	S173	A174P	174	Missense	proximal	1	no	7.353	18.379	EPSD	COSMIC	8.808	Gain
CMGC_CDK_CDK5_CDK5_ST	Q96KR7	PHACTR3	Q00535	CDK5	S216	D212E	212	Missense	distal	-4	no	18.743	18.792	EPSD	COSMIC	8.808	Up-regulation
CMGC_CDK_CDK5_CDK5_ST	Q96KR7	PHACTR3	Q00535	CDK5	S216	A209V	209	Missense	distal	-7	no	18.743	18.779	EPSD	COSMIC	8.808	Up-regulation
CMGC_CDK_CDK5_CDK5_ST	Q96KR7	PHACTR3	Q00535	CDK5	S216	D215E	215	Missense	proximal	-1	no	18.743	18.744	EPSD	COSMIC	8.808	Up-regulation
CMGC_CDK_CDK5_CDK5_ST	Q96KR7	PHACTR3	Q00535	CDK5	S216	R223I	223	Missense	distal	7	no	18.743	18.734	EPSD	COSMIC	8.808	Down-regulation
CMGC_CDK_CDK5_CDK5_ST	Q96KR7	PHACTR3	Q00535	CDK5	S216	P217L	217	Missense	proximal	1	no	18.743	6.793	EPSD	COSMIC	8.808	Loss
CMGC_CDK_CDK5_CDK5_ST	Q96KR7	PHACTR3	Q00535	CDK5	S216	L214M	214	Missense	proximal	-2	no	18.743	18.585	EPSD	COSMIC	8.808	Down-regulation
CMGC_CDK_CDK5_CDK5_ST	Q96KR7	PHACTR3	Q00535	CDK5	S230	P235Q	235	Missense	distal	5	no	16.683	16.633	EPSD	COSMIC	8.808	Down-regulation
CMGC_CDK_CDK5_CDK5_ST	Q96KR7	PHACTR3	Q00535	CDK5	S230	P237L	237	Missense	distal	7	no	16.683	16.671	EPSD	COSMIC	8.808	Down-regulation
CMGC_CDK_CDK5_CDK5_ST	Q96KR7	PHACTR3	Q00535	CDK5	S230	L228P	228	Missense	proximal	-2	no	16.683	17.098	EPSD	COSMIC	8.808	Up-regulation
CMGC_CDK_CDK5_CDK5_ST	Q96KR7	PHACTR3	Q00535	CDK5	S230	L233M	233	Missense	distal	3	no	16.683	16.793	EPSD	COSMIC	8.808	Up-regulation
CMGC_CDK_CDK5_CDK5_ST	Q96KR7	PHACTR3	Q00535	CDK5	S230	R223I	223	Missense	distal	-7	no	16.683	16.649	EPSD	COSMIC	8.808	Down-regulation
CMGC_CDK_CDK5_CDK5_ST	Q96KR7	PHACTR3	Q00535	CDK5	S230	P229S	229	Missense	proximal	-1	no	16.683	16.684	EPSD	COSMIC	8.808	Up-regulation
CMGC_CDK_CDK5_CDK5_ST	Q96KR7	PHACTR3	Q00535	CDK5	T236	P235Q	235	Missense	proximal	-1	no	17.851	17.850	EPSD	COSMIC	8.808	Down-regulation
CMGC_CDK_CDK5_CDK5_ST	Q96KR7	PHACTR3	Q00535	CDK5	T236	P237L	237	Missense	proximal	1	no	17.851	5.901	EPSD	COSMIC	8.808	Loss
CMGC_CDK_CDK5_CDK5_ST	Q96KR7	PHACTR3	Q00535	CDK5	T236	L233M	233	Missense	distal	-3	no	17.851	17.842	EPSD	COSMIC	8.808	Down-regulation
CMGC_CDK_CDK5_CDK5_ST	Q96KR7	PHACTR3	Q00535	CDK5	T236	P229S	229	Missense	distal	-7	no	17.851	17.855	EPSD	COSMIC	8.808	Up-regulation
CMGC_CDK_CDK5_CDK5_ST	Q96KR7	PHACTR3	Q00535	CDK5	T236	P238Q	238	Missense	proximal	2	no	17.851	17.793	EPSD	COSMIC	8.808	Down-regulation
CMGC_CDK_CDK5_CDK5_ST	Q96KR7	PHACTR3	Q00535	CDK5	T236	P238L	238	Missense	proximal	2	no	17.851	17.686	EPSD	COSMIC	8.808	Down-regulation
CMGC_CDK_CDK5_CDK5_ST	Q96KR7	PHACTR3	Q00535	CDK5	T236	P238S	238	Missense	proximal	2	no	17.851	17.833	EPSD	COSMIC	8.808	Down-regulation
CMGC_CDK_CDK5_CDK5_ST	Q96KR7	PHACTR3	Q00535	CDK5	S259	S260R	260	Missense	proximal	1	no	6.589	9.543	EPSD	COSMIC	8.808	Gain
CMGC_CDK_CDK5_CDK5_ST	Q96KR7	PHACTR3	Q00535	CDK5	T274	S278Y	278	Missense	distal	4	no	16.467	16.382	EPSD	COSMIC	8.808	Down-regulation
CMGC_CDK_CDK5_CDK5_ST	Q96KR7	PHACTR3	Q00535	CDK5	T274	S267Y	267	Missense	distal	-7	no	16.467	16.401	EPSD	COSMIC;GDSC;CCLE	8.808	Down-regulation
CMGC_CDK_CDK5_CDK5_ST	Q96KR7	PHACTR3	Q00535	CDK5	T274	R269W	269	Missense	distal	-5	no	16.467	16.208	EPSD	COSMIC	8.808	Down-regulation
CMGC_CDK_CDK5_CDK5_ST	Q96KR7	PHACTR3	Q00535	CDK5	T274	R269L	269	Missense	distal	-5	no	16.467	16.167	EPSD	COSMIC	8.808	Down-regulation
CMGC_CDK_CDK5_CDK5_ST	Q96KR7	PHACTR3	Q00535	CDK5	T274	L268F	268	Missense	distal	-6	no	16.467	16.416	EPSD	COSMIC	8.808	Down-regulation
CMGC_CDK_CDK5_CDK5_ST	Q96KR7	PHACTR3	Q00535	CDK5	T274	P279L	279	Missense	distal	5	no	16.467	16.294	EPSD	COSMIC	8.808	Down-regulation
CMGC_CDK_CDK5_CDK5_ST	Q96KR7	PHACTR3	Q00535	CDK5	T274	P279S	279	Missense	distal	5	no	16.467	16.479	EPSD	COSMIC	8.808	Up-regulation
CMGC_CDK_CDK5_CDK5_ST	Q96KR7	PHACTR3	Q00535	CDK5	S278	S278Y	278	Missense	central	0	yes	17.242	0.000	EPSD	COSMIC	8.808	Loss
CMGC_CDK_CDK5_CDK5_ST	Q96KR7	PHACTR3	Q00535	CDK5	S278	P279L	279	Missense	proximal	1	no	17.242	5.292	EPSD	COSMIC	8.808	Loss
CMGC_CDK_CDK5_CDK5_ST	Q96KR7	PHACTR3	Q00535	CDK5	S278	P279S	279	Missense	proximal	1	no	17.242	5.340	EPSD	COSMIC	8.808	Loss
CMGC_CDK_CDK5_CDK5_ST	Q96KR7	PHACTR3	Q00535	CDK5	S291	P287Q	287	Missense	distal	-4	no	8.927	8.802	EPSD	COSMIC	8.808	Loss
CMGC_CDK_CDK5_CDK5_ST	Q96KR7	PHACTR3	Q00535	CDK5	S291	E296G	296	Missense	distal	5	no	8.927	8.936	EPSD	COSMIC	8.808	Up-regulation
CMGC_CDK_CDK5_CDK5_ST	Q96KR7	PHACTR3	Q00535	CDK5	S291	H298Y	298	Missense	distal	7	no	8.927	8.918	EPSD	COSMIC;CCLE	8.808	Down-regulation
CMGC_CDK_CDK5_CDK5_ST	Q96KR7	PHACTR3	Q00535	CDK5	S291	P290Q	290	Missense	proximal	-1	no	8.927	8.926	EPSD	COSMIC	8.808	Down-regulation
CMGC_CDK_CDK5_CDK5_ST	Q96KR7	PHACTR3	Q00535	CDK5	S291	P289S	289	Missense	proximal	-2	no	8.927	8.828	EPSD	COSMIC	8.808	Down-regulation
CMGC_CDK_CDK5_CDK5_ST	Q96KR7	PHACTR3	Q00535	CDK5	S291	E296V	296	Missense	distal	5	no	8.927	9.002	EPSD	COSMIC	8.808	Up-regulation
CMGC_CDK_CDK5_CDK5_ST	Q96KR7	PHACTR3	Q00535	CDK5	S291	R286W	286	Missense	distal	-5	no	8.927	8.668	EPSD	COSMIC	8.808	Loss
CMGC_CDK_CDK5_CDK5_ST	Q96KR7	PHACTR3	Q00535	CDK5	S318	R322W	322	Missense	distal	4	no	19.725	19.653	PhosphoSitePlus	COSMIC;GDSC	8.808	Down-regulation
CMGC_CDK_CDK5_CDK5_ST	Q96KR7	PHACTR3	Q00535	CDK5	S318	D324H	324	Missense	distal	6	no	19.725	19.732	PhosphoSitePlus	COSMIC	8.808	Up-regulation
CMGC_CDK_CDK5_CDK5_ST	Q96KR7	PHACTR3	Q00535	CDK5	S318	G312R	312	Missense	distal	-6	no	19.725	19.826	PhosphoSitePlus	COSMIC	8.808	Up-regulation
CMGC_CDK_CDK5_CDK5_ST	Q96KR7	PHACTR3	Q00535	CDK5	S318	K316E	316	Missense	proximal	-2	no	19.725	19.312	PhosphoSitePlus	COSMIC	8.808	Down-regulation
CMGC_CDK_CDK5_CDK5_ST	Q96KR7	PHACTR3	Q00535	CDK5	S318	K316N	316	Missense	proximal	-2	no	19.725	19.541	PhosphoSitePlus	COSMIC	8.808	Down-regulation
CMGC_CDK_CDK5_CDK5_ST	Q96KR7	PHACTR3	Q00535	CDK5	S328	S328F	328	Missense	central	0	yes	9.417	0.000	EPSD	COSMIC	8.808	Loss
CMGC_CDK_CDK5_CDK5_ST	Q96KR7	PHACTR3	Q00535	CDK5	S328	V333G	333	Missense	distal	5	no	9.417	9.351	EPSD	COSMIC	8.808	Down-regulation
CMGC_CDK_CDK5_CDK5_ST	Q96KR7	PHACTR3	Q00535	CDK5	S328	R322W	322	Missense	distal	-6	no	9.417	9.311	EPSD	COSMIC;GDSC	8.808	Down-regulation
CMGC_CDK_CDK5_CDK5_ST	Q96KR7	PHACTR3	Q00535	CDK5	S328	E334K	334	Missense	distal	6	no	9.417	9.436	EPSD	COSMIC	8.808	Up-regulation
CMGC_CDK_CDK5_CDK5_ST	Q96KR7	PHACTR3	Q00535	CDK5	S328	D324H	324	Missense	distal	-4	no	9.417	9.413	EPSD	COSMIC	8.808	Down-regulation
CMGC_CDK_CDK5_CDK5_ST	Q96KR7	PHACTR3	Q00535	CDK5	S328	R326C	326	Missense	proximal	-2	no	9.417	8.901	EPSD	COSMIC	8.808	Down-regulation
CMGC_CDK_CDK5_CDK5_ST	Q96KR7	PHACTR3	Q00535	CDK5	S328	R335W	335	Missense	distal	7	no	9.417	9.406	EPSD	COSMIC	8.808	Down-regulation
CMGC_CDK_CDK5_CDK5_ST	Q96KR7	PHACTR3	Q00535	CDK5	S328	S331F	331	Missense	distal	3	no	9.417	8.240	EPSD	COSMIC	8.808	Loss
CMGC_CDK_CDK5_CDK5_ST	Q96KR7	PHACTR3	Q00535	CDK5	S328	V333M	333	Missense	distal	5	no	9.417	9.251	EPSD	COSMIC	8.808	Down-regulation
CMGC_CDK_CDK5_CDK5_ST	Q96KR7	PHACTR3	Q00535	CDK5	S328	R335Q	335	Missense	distal	7	no	9.417	9.412	EPSD	COSMIC	8.808	Down-regulation
CMGC_CDK_CDK5_CDK5_ST	P01106	MYC	Q00535	CDK5	T8	N9H	9	Missense	proximal	1	no	8.962	-0.311	EPSD	COSMIC	8.808	Loss
CMGC_CDK_CDK5_CDK5_ST	P01106	MYC	Q00535	CDK5	T8	N11S	11	Missense	distal	3	no	8.962	9.158	EPSD	COSMIC	8.808	Up-regulation
CMGC_CDK_CDK5_CDK5_ST	P01106	MYC	Q00535	CDK5	T8	Y12C	12	Missense	distal	4	no	8.962	8.956	EPSD	COSMIC	8.808	Down-regulation
CMGC_CDK_CDK5_CDK5_ST	P01106	MYC	Q00535	CDK5	T8	N11Y	11	Missense	distal	3	no	8.962	8.389	EPSD	COSMIC	8.808	Loss
CMGC_CDK_CDK5_CDK5_ST	P01106	MYC	Q00535	CDK5	T8	F7L	7	Missense	proximal	-1	no	8.962	8.965	EPSD	COSMIC	8.808	Up-regulation
CMGC_CDK_CDK5_CDK5_ST	P01106	MYC	Q00535	CDK5	T8	S6R	6	Missense	proximal	-2	no	8.962	9.007	EPSD	COSMIC	8.808	Up-regulation
CMGC_CDK_CDK5_CDK5_ST	P01106	MYC	Q00535	CDK5	T8	N11D	11	Missense	distal	3	no	8.962	8.543	EPSD	COSMIC	8.808	Loss
CMGC_CDK_CDK5_CDK5_ST	P01106	MYC	Q00535	CDK5	T8	P2S	2	Missense	distal	-6	no	8.962	9.002	EPSD	COSMIC	8.808	Up-regulation
CMGC_CDK_CDK5_CDK5_ST	P01106	MYC	Q00535	CDK5	T8	S6N	6	Missense	proximal	-2	no	8.962	8.849	EPSD	COSMIC;CCLE	8.808	Down-regulation
CMGC_CDK_CDK5_CDK5_ST	P01106	MYC	Q00535	CDK5	T8	S6T	6	Missense	proximal	-2	no	8.962	8.922	EPSD	COSMIC;CCLE	8.808	Down-regulation
CMGC_CDK_CDK5_CDK5_ST	P01106	MYC	Q00535	CDK5	T8	V5I	5	Missense	distal	-3	no	8.962	8.947	EPSD	COSMIC;CCLE	8.808	Down-regulation
CMGC_CDK_CDK5_CDK5_ST	P01106	MYC	Q00535	CDK5	T8	V5A	5	Missense	distal	-3	no	8.962	8.924	EPSD	COSMIC;CCLE	8.808	Down-regulation
CMGC_CDK_CDK5_CDK5_ST	P01106	MYC	Q00535	CDK5	T8	R10K	10	Missense	proximal	2	no	8.962	9.011	EPSD	COSMIC	8.808	Up-regulation
CMGC_CDK_CDK5_CDK5_ST	P01106	MYC	Q00535	CDK5	T8	F7I	7	Missense	proximal	-1	no	8.962	8.967	EPSD	COSMIC	8.808	Up-regulation
CMGC_CDK_CDK5_CDK5_ST	P01106	MYC	Q00535	CDK5	T8	R10G	10	Missense	proximal	2	no	8.962	8.790	EPSD	COSMIC	8.808	Loss
CMGC_CDK_CDK5_CDK5_ST	P01106	MYC	Q00535	CDK5	T8	L14V	14	Missense	distal	6	no	8.962	8.974	EPSD	COSMIC	8.808	Up-regulation
CMGC_CDK_CDK5_CDK5_ST	P01106	MYC	Q00535	CDK5	T8	R10M	10	Missense	proximal	2	no	8.962	8.690	EPSD	COSMIC	8.808	Loss
CMGC_CDK_CDK5_CDK5_ST	P01106	MYC	Q00535	CDK5	T8	L3R	3	Missense	distal	-5	no	8.962	9.263	EPSD	COSMIC	8.808	Up-regulation
CMGC_CDK_CDK5_CDK5_ST	P01106	MYC	Q00535	CDK5	T8	N9S	9	Missense	proximal	1	no	8.962	6.300	EPSD	COSMIC	8.808	Loss
CMGC_CDK_CDK5_CDK5_ST	P01106	MYC	Q00535	CDK5	T8	Y12S	12	Missense	distal	4	no	8.962	9.048	EPSD	COSMIC;CCLE	8.808	Up-regulation
CMGC_CDK_CDK5_CDK5_ST	P01106	MYC	Q00535	CDK5	T8	R10W	10	Missense	proximal	2	no	8.962	8.771	EPSD	COSMIC	8.808	Loss
CMGC_CDK_CDK5_CDK5_ST	P01106	MYC	Q00535	CDK5	T8	L3F	3	Missense	distal	-5	no	8.962	8.853	EPSD	COSMIC	8.808	Down-regulation
CMGC_CDK_CDK5_CDK5_ST	P01106	MYC	Q00535	CDK5	T8	S6D	6	Missense	proximal	-2	no	8.962	8.727	EPSD	COSMIC	8.808	Loss
CMGC_CDK_CDK5_CDK5_ST	P01106	MYC	Q00535	CDK5	T8	S6G	6	Missense	proximal	-2	no	8.962	8.597	EPSD	COSMIC	8.808	Loss
CMGC_CDK_CDK5_CDK5_ST	P01106	MYC	Q00535	CDK5	T8	L14F	14	Missense	distal	6	no	8.962	8.957	EPSD	COSMIC	8.808	Down-regulation
CMGC_CDK_CDK5_CDK5_ST	P01106	MYC	Q00535	CDK5	T8	Y12N	12	Missense	distal	4	no	8.962	9.017	EPSD	COSMIC	8.808	Up-regulation
CMGC_CDK_CDK5_CDK5_ST	P01106	MYC	Q00535	CDK5	T58	P57S	57	Missense	proximal	-1	no	15.918	15.920	EPSD	COSMIC;CCLE	8.808	Up-regulation
CMGC_CDK_CDK5_CDK5_ST	P01106	MYC	Q00535	CDK5	T58	S62P	62	Missense	distal	4	no	15.918	15.917	EPSD	COSMIC;CCLE	8.808	Down-regulation
CMGC_CDK_CDK5_CDK5_ST	P01106	MYC	Q00535	CDK5	T58	P59L	59	Missense	proximal	1	no	15.918	3.969	EPSD	COSMIC;CCLE	8.808	Loss
CMGC_CDK_CDK5_CDK5_ST	P01106	MYC	Q00535	CDK5	T58	T58N	58	Missense	central	0	yes	15.918	0.000	EPSD	COSMIC;CCLE	8.808	Loss
CMGC_CDK_CDK5_CDK5_ST	P01106	MYC	Q00535	CDK5	T58	P60H	60	Missense	proximal	2	no	15.918	15.885	EPSD	COSMIC;CCLE	8.808	Down-regulation
CMGC_CDK_CDK5_CDK5_ST	P01106	MYC	Q00535	CDK5	T58	P63L	63	Missense	distal	5	no	15.918	15.746	EPSD	COSMIC	8.808	Down-regulation
CMGC_CDK_CDK5_CDK5_ST	P01106	MYC	Q00535	CDK5	T58	P63H	63	Missense	distal	5	no	15.918	15.890	EPSD	COSMIC	8.808	Down-regulation
CMGC_CDK_CDK5_CDK5_ST	P01106	MYC	Q00535	CDK5	T58	T58A	58	Missense	central	0	yes	15.918	0.000	EPSD	COSMIC;CCLE	8.808	Loss
CMGC_CDK_CDK5_CDK5_ST	P01106	MYC	Q00535	CDK5	T58	P59A	59	Missense	proximal	1	no	15.918	4.892	EPSD	COSMIC;CCLE	8.808	Loss
CMGC_CDK_CDK5_CDK5_ST	P01106	MYC	Q00535	CDK5	T58	P59R	59	Missense	proximal	1	no	15.918	6.971	EPSD	COSMIC	8.808	Loss
CMGC_CDK_CDK5_CDK5_ST	P01106	MYC	Q00535	CDK5	T58	P60A	60	Missense	proximal	2	no	15.918	15.806	EPSD	COSMIC;CCLE	8.808	Down-regulation
CMGC_CDK_CDK5_CDK5_ST	P01106	MYC	Q00535	CDK5	T58	P59S	59	Missense	proximal	1	no	15.918	4.017	EPSD	COSMIC;CCLE	8.808	Loss
CMGC_CDK_CDK5_CDK5_ST	P01106	MYC	Q00535	CDK5	T58	S62F	62	Missense	distal	4	no	15.918	15.806	EPSD	COSMIC	8.808	Down-regulation
CMGC_CDK_CDK5_CDK5_ST	P01106	MYC	Q00535	CDK5	T58	T58I	58	Missense	central	0	yes	15.918	0.000	EPSD	COSMIC;CCLE	8.808	Loss
CMGC_CDK_CDK5_CDK5_ST	P01106	MYC	Q00535	CDK5	T58	K51N	51	Missense	distal	-7	no	15.918	15.875	EPSD	COSMIC	8.808	Down-regulation
CMGC_CDK_CDK5_CDK5_ST	P01106	MYC	Q00535	CDK5	T58	T58P	58	Missense	central	0	yes	15.918	0.000	EPSD	COSMIC	8.808	Loss
CMGC_CDK_CDK5_CDK5_ST	P01106	MYC	Q00535	CDK5	T58	S64R	64	Missense	distal	6	no	15.918	15.925	EPSD	COSMIC;CCLE	8.808	Up-regulation
CMGC_CDK_CDK5_CDK5_ST	P01106	MYC	Q00535	CDK5	T58	P57L	57	Missense	proximal	-1	no	15.918	15.914	EPSD	COSMIC;CCLE	8.808	Down-regulation
CMGC_CDK_CDK5_CDK5_ST	P01106	MYC	Q00535	CDK5	T58	P63S	63	Missense	distal	5	no	15.918	15.931	EPSD	COSMIC;CCLE	8.808	Up-regulation
CMGC_CDK_CDK5_CDK5_ST	P01106	MYC	Q00535	CDK5	T58	P57F	57	Missense	proximal	-1	no	15.918	15.911	EPSD	COSMIC	8.808	Down-regulation
CMGC_CDK_CDK5_CDK5_ST	P01106	MYC	Q00535	CDK5	T58	P59Q	59	Missense	proximal	1	no	15.918	6.942	EPSD	COSMIC;CCLE	8.808	Loss
CMGC_CDK_CDK5_CDK5_ST	P01106	MYC	Q00535	CDK5	T58	P59T	59	Missense	proximal	1	no	15.918	5.431	EPSD	COSMIC	8.808	Loss
CMGC_CDK_CDK5_CDK5_ST	P01106	MYC	Q00535	CDK5	T58	P60S	60	Missense	proximal	2	no	15.918	15.901	EPSD	COSMIC	8.808	Down-regulation
CMGC_CDK_CDK5_CDK5_ST	P01106	MYC	Q00535	CDK5	T58	P63A	63	Missense	distal	5	no	15.918	15.796	EPSD	COSMIC	8.808	Down-regulation
CMGC_CDK_CDK5_CDK5_ST	P01106	MYC	Q00535	CDK5	T58	S64N	64	Missense	distal	6	no	15.918	15.913	EPSD	COSMIC	8.808	Down-regulation
CMGC_CDK_CDK5_CDK5_ST	P01106	MYC	Q00535	CDK5	T58	P60L	60	Missense	proximal	2	no	15.918	15.753	EPSD	COSMIC	8.808	Down-regulation
CMGC_CDK_CDK5_CDK5_ST	P01106	MYC	Q00535	CDK5	T58	P57A	57	Missense	proximal	-1	no	15.918	15.914	EPSD	COSMIC	8.808	Down-regulation
CMGC_CDK_CDK5_CDK5_ST	P01106	MYC	Q00535	CDK5	T58	L56V	56	Missense	proximal	-2	no	15.918	16.152	EPSD	COSMIC	8.808	Up-regulation
CMGC_CDK_CDK5_CDK5_ST	P01106	MYC	Q00535	CDK5	T58	P63R	63	Missense	distal	5	no	15.918	15.994	EPSD	COSMIC	8.808	Up-regulation
CMGC_CDK_CDK5_CDK5_ST	P01106	MYC	Q00535	CDK5	T58	L56M	56	Missense	proximal	-2	no	15.918	15.760	EPSD	COSMIC	8.808	Down-regulation
CMGC_CDK_CDK5_CDK5_ST	P01106	MYC	Q00535	CDK5	T58	P63T	63	Missense	distal	5	no	15.918	15.930	EPSD	COSMIC	8.808	Up-regulation
CMGC_CDK_CDK5_CDK5_ST	P01106	MYC	Q00535	CDK5	T58	S62A	62	Missense	distal	4	no	15.918	15.856	EPSD	COSMIC	8.808	Down-regulation
CMGC_CDK_CDK5_CDK5_ST	P01106	MYC	Q00535	CDK5	T58	P57R	57	Missense	proximal	-1	no	15.918	15.919	EPSD	COSMIC	8.808	Up-regulation
CMGC_CDK_CDK5_CDK5_ST	P01106	MYC	Q00535	CDK5	T58	P60T	60	Missense	proximal	2	no	15.918	15.925	EPSD	COSMIC;CCLE	8.808	Up-regulation
CMGC_CDK_CDK5_CDK5_ST	P01106	MYC	Q00535	CDK5	T58	E54V	54	Missense	distal	-4	no	15.918	16.064	EPSD	COSMIC	8.808	Up-regulation
CMGC_CDK_CDK5_CDK5_ST	P01106	MYC	Q00535	CDK5	T58	S64T	64	Missense	distal	6	no	15.918	15.919	EPSD	COSMIC	8.808	Up-regulation
CMGC_CDK_CDK5_CDK5_ST	P01106	MYC	Q00535	CDK5	T58	R65C	65	Missense	distal	7	no	15.918	15.902	EPSD	COSMIC	8.808	Down-regulation
CMGC_CDK_CDK5_CDK5_ST	P01106	MYC	Q00535	CDK5	T58	L55P	55	Missense	distal	-3	no	15.918	15.979	EPSD	COSMIC	8.808	Up-regulation
CMGC_CDK_CDK5_CDK5_ST	P01106	MYC	Q00535	CDK5	T58	L55M	55	Missense	distal	-3	no	15.918	15.909	EPSD	COSMIC	8.808	Down-regulation
CMGC_CDK_CDK5_CDK5_ST	P01106	MYC	Q00535	CDK5	T58	E54A	54	Missense	distal	-4	no	15.918	15.644	EPSD	COSMIC	8.808	Down-regulation
CMGC_CDK_CDK5_CDK5_ST	P01106	MYC	Q00535	CDK5	S62	P57S	57	Missense	distal	-5	no	19.881	19.903	PhosphoSitePlus	COSMIC;CCLE	8.808	Up-regulation
CMGC_CDK_CDK5_CDK5_ST	P01106	MYC	Q00535	CDK5	S62	S62P	62	Missense	central	0	yes	19.881	0.000	PhosphoSitePlus	COSMIC;CCLE	8.808	Loss
CMGC_CDK_CDK5_CDK5_ST	P01106	MYC	Q00535	CDK5	S62	P59L	59	Missense	distal	-3	no	19.881	19.820	PhosphoSitePlus	COSMIC;CCLE	8.808	Down-regulation
CMGC_CDK_CDK5_CDK5_ST	P01106	MYC	Q00535	CDK5	S62	T58N	58	Missense	distal	-4	no	19.881	19.870	PhosphoSitePlus	COSMIC;CCLE	8.808	Down-regulation
CMGC_CDK_CDK5_CDK5_ST	P01106	MYC	Q00535	CDK5	S62	P60H	60	Missense	proximal	-2	no	19.881	19.565	PhosphoSitePlus	COSMIC;CCLE	8.808	Down-regulation
CMGC_CDK_CDK5_CDK5_ST	P01106	MYC	Q00535	CDK5	S62	P63L	63	Missense	proximal	1	no	19.881	7.931	PhosphoSitePlus	COSMIC	8.808	Loss
CMGC_CDK_CDK5_CDK5_ST	P01106	MYC	Q00535	CDK5	S62	P63H	63	Missense	proximal	1	no	19.881	1.369	PhosphoSitePlus	COSMIC	8.808	Loss
CMGC_CDK_CDK5_CDK5_ST	P01106	MYC	Q00535	CDK5	S62	T58A	58	Missense	distal	-4	no	19.881	19.481	PhosphoSitePlus	COSMIC;CCLE	8.808	Down-regulation
CMGC_CDK_CDK5_CDK5_ST	P01106	MYC	Q00535	CDK5	S62	P59A	59	Missense	distal	-3	no	19.881	19.829	PhosphoSitePlus	COSMIC;CCLE	8.808	Down-regulation
CMGC_CDK_CDK5_CDK5_ST	P01106	MYC	Q00535	CDK5	S62	P59R	59	Missense	distal	-3	no	19.881	19.890	PhosphoSitePlus	COSMIC	8.808	Up-regulation
CMGC_CDK_CDK5_CDK5_ST	P01106	MYC	Q00535	CDK5	S62	P60A	60	Missense	proximal	-2	no	19.881	19.504	PhosphoSitePlus	COSMIC;CCLE	8.808	Down-regulation
CMGC_CDK_CDK5_CDK5_ST	P01106	MYC	Q00535	CDK5	S62	P57T	57	Missense	distal	-5	no	19.881	19.878	PhosphoSitePlus	COSMIC;CCLE	8.808	Down-regulation
CMGC_CDK_CDK5_CDK5_ST	P01106	MYC	Q00535	CDK5	S62	P59S	59	Missense	distal	-3	no	19.881	19.875	PhosphoSitePlus	COSMIC;CCLE	8.808	Down-regulation
CMGC_CDK_CDK5_CDK5_ST	P01106	MYC	Q00535	CDK5	S62	S62F	62	Missense	central	0	yes	19.881	0.000	PhosphoSitePlus	COSMIC	8.808	Loss
CMGC_CDK_CDK5_CDK5_ST	P01106	MYC	Q00535	CDK5	S62	T58I	58	Missense	distal	-4	no	19.881	19.768	PhosphoSitePlus	COSMIC;CCLE	8.808	Down-regulation
CMGC_CDK_CDK5_CDK5_ST	P01106	MYC	Q00535	CDK5	S62	T58P	58	Missense	distal	-4	no	19.881	20.037	PhosphoSitePlus	COSMIC	8.808	Up-regulation
CMGC_CDK_CDK5_CDK5_ST	P01106	MYC	Q00535	CDK5	S62	S64R	64	Missense	proximal	2	no	19.881	19.980	PhosphoSitePlus	COSMIC;CCLE	8.808	Up-regulation
CMGC_CDK_CDK5_CDK5_ST	P01106	MYC	Q00535	CDK5	S62	P57L	57	Missense	distal	-5	no	19.881	19.684	PhosphoSitePlus	COSMIC;CCLE	8.808	Down-regulation
CMGC_CDK_CDK5_CDK5_ST	P01106	MYC	Q00535	CDK5	S62	P63S	63	Missense	proximal	1	no	19.881	7.980	PhosphoSitePlus	COSMIC;CCLE	8.808	Loss
CMGC_CDK_CDK5_CDK5_ST	P01106	MYC	Q00535	CDK5	S62	R66H	66	Missense	distal	4	no	19.881	19.841	PhosphoSitePlus	COSMIC	8.808	Down-regulation
CMGC_CDK_CDK5_CDK5_ST	P01106	MYC	Q00535	CDK5	S62	P57F	57	Missense	distal	-5	no	19.881	19.574	PhosphoSitePlus	COSMIC	8.808	Down-regulation
CMGC_CDK_CDK5_CDK5_ST	P01106	MYC	Q00535	CDK5	S62	P59Q	59	Missense	distal	-3	no	19.881	19.864	PhosphoSitePlus	COSMIC;CCLE	8.808	Down-regulation
CMGC_CDK_CDK5_CDK5_ST	P01106	MYC	Q00535	CDK5	S62	P59T	59	Missense	distal	-3	no	19.881	19.874	PhosphoSitePlus	COSMIC	8.808	Down-regulation
CMGC_CDK_CDK5_CDK5_ST	P01106	MYC	Q00535	CDK5	S62	P60S	60	Missense	proximal	-2	no	19.881	19.782	PhosphoSitePlus	COSMIC	8.808	Down-regulation
CMGC_CDK_CDK5_CDK5_ST	P01106	MYC	Q00535	CDK5	S62	P63A	63	Missense	proximal	1	no	19.881	8.855	PhosphoSitePlus	COSMIC	8.808	Down-regulation
CMGC_CDK_CDK5_CDK5_ST	P01106	MYC	Q00535	CDK5	S62	S64N	64	Missense	proximal	2	no	19.881	19.835	PhosphoSitePlus	COSMIC	8.808	Down-regulation
CMGC_CDK_CDK5_CDK5_ST	P01106	MYC	Q00535	CDK5	S62	P60L	60	Missense	proximal	-2	no	19.881	19.466	PhosphoSitePlus	COSMIC	8.808	Down-regulation
CMGC_CDK_CDK5_CDK5_ST	P01106	MYC	Q00535	CDK5	S62	P57A	57	Missense	distal	-5	no	19.881	19.722	PhosphoSitePlus	COSMIC	8.808	Down-regulation
CMGC_CDK_CDK5_CDK5_ST	P01106	MYC	Q00535	CDK5	S62	L56V	56	Missense	distal	-6	no	19.881	19.959	PhosphoSitePlus	COSMIC	8.808	Up-regulation
CMGC_CDK_CDK5_CDK5_ST	P01106	MYC	Q00535	CDK5	S62	P63R	63	Missense	proximal	1	no	19.881	10.934	PhosphoSitePlus	COSMIC	8.808	Down-regulation
CMGC_CDK_CDK5_CDK5_ST	P01106	MYC	Q00535	CDK5	S62	L56M	56	Missense	distal	-6	no	19.881	19.854	PhosphoSitePlus	COSMIC	8.808	Down-regulation
CMGC_CDK_CDK5_CDK5_ST	P01106	MYC	Q00535	CDK5	S62	L69V	69	Missense	distal	7	no	19.881	19.890	PhosphoSitePlus	COSMIC	8.808	Up-regulation
CMGC_CDK_CDK5_CDK5_ST	P01106	MYC	Q00535	CDK5	S62	P63T	63	Missense	proximal	1	no	19.881	9.394	PhosphoSitePlus	COSMIC	8.808	Down-regulation
CMGC_CDK_CDK5_CDK5_ST	P01106	MYC	Q00535	CDK5	S62	S67F	67	Missense	distal	5	no	19.881	19.642	PhosphoSitePlus	COSMIC	8.808	Down-regulation
CMGC_CDK_CDK5_CDK5_ST	P01106	MYC	Q00535	CDK5	S62	S62A	62	Missense	central	0	yes	19.881	0.000	PhosphoSitePlus	COSMIC	8.808	Loss
CMGC_CDK_CDK5_CDK5_ST	P01106	MYC	Q00535	CDK5	S62	P57R	57	Missense	distal	-5	no	19.881	19.984	PhosphoSitePlus	COSMIC	8.808	Up-regulation
CMGC_CDK_CDK5_CDK5_ST	P01106	MYC	Q00535	CDK5	S62	L69P	69	Missense	distal	7	no	19.881	19.893	PhosphoSitePlus	COSMIC	8.808	Up-regulation
CMGC_CDK_CDK5_CDK5_ST	P01106	MYC	Q00535	CDK5	S62	P60T	60	Missense	proximal	-2	no	19.881	19.742	PhosphoSitePlus	COSMIC;CCLE	8.808	Down-regulation
CMGC_CDK_CDK5_CDK5_ST	P01106	MYC	Q00535	CDK5	S62	L69F	69	Missense	distal	7	no	19.881	19.876	PhosphoSitePlus	COSMIC	8.808	Down-regulation
CMGC_CDK_CDK5_CDK5_ST	P01106	MYC	Q00535	CDK5	S62	S64T	64	Missense	proximal	2	no	19.881	19.906	PhosphoSitePlus	COSMIC	8.808	Up-regulation
CMGC_CDK_CDK5_CDK5_ST	P01106	MYC	Q00535	CDK5	S62	R65C	65	Missense	distal	3	no	19.881	17.585	PhosphoSitePlus	COSMIC	8.808	Down-regulation
CMGC_CDK_CDK5_CDK5_ST	P01106	MYC	Q00535	CDK5	S62	L55P	55	Missense	distal	-7	no	19.881	19.933	PhosphoSitePlus	COSMIC	8.808	Up-regulation
CMGC_CDK_CDK5_CDK5_ST	P01106	MYC	Q00535	CDK5	S62	L55M	55	Missense	distal	-7	no	19.881	19.865	PhosphoSitePlus	COSMIC	8.808	Down-regulation
CMGC_CDK_CDK5_CDK5_ST	P01106	MYC	Q00535	CDK5	S64	P57S	57	Missense	distal	-7	no	9.314	9.318	EPSD	COSMIC;CCLE	8.808	Up-regulation
CMGC_CDK_CDK5_CDK5_ST	P01106	MYC	Q00535	CDK5	S64	S62P	62	Missense	proximal	-2	no	9.314	9.412	EPSD	COSMIC;CCLE	8.808	Up-regulation
CMGC_CDK_CDK5_CDK5_ST	P01106	MYC	Q00535	CDK5	S64	P59L	59	Missense	distal	-5	no	9.314	9.116	EPSD	COSMIC;CCLE	8.808	Down-regulation
CMGC_CDK_CDK5_CDK5_ST	P01106	MYC	Q00535	CDK5	S64	T58N	58	Missense	distal	-6	no	9.314	9.283	EPSD	COSMIC;CCLE	8.808	Down-regulation
CMGC_CDK_CDK5_CDK5_ST	P01106	MYC	Q00535	CDK5	S64	P60H	60	Missense	distal	-4	no	9.314	8.979	EPSD	COSMIC;CCLE	8.808	Down-regulation
CMGC_CDK_CDK5_CDK5_ST	P01106	MYC	Q00535	CDK5	S64	P63L	63	Missense	proximal	-1	no	9.314	9.309	EPSD	COSMIC	8.808	Down-regulation
CMGC_CDK_CDK5_CDK5_ST	P01106	MYC	Q00535	CDK5	S64	P63H	63	Missense	proximal	-1	no	9.314	9.312	EPSD	COSMIC	8.808	Down-regulation
CMGC_CDK_CDK5_CDK5_ST	P01106	MYC	Q00535	CDK5	S64	T58A	58	Missense	distal	-6	no	9.314	9.227	EPSD	COSMIC;CCLE	8.808	Down-regulation
CMGC_CDK_CDK5_CDK5_ST	P01106	MYC	Q00535	CDK5	S64	P59A	59	Missense	distal	-5	no	9.314	9.154	EPSD	COSMIC;CCLE	8.808	Down-regulation
CMGC_CDK_CDK5_CDK5_ST	P01106	MYC	Q00535	CDK5	S64	P59R	59	Missense	distal	-5	no	9.314	9.416	EPSD	COSMIC	8.808	Up-regulation
CMGC_CDK_CDK5_CDK5_ST	P01106	MYC	Q00535	CDK5	S64	P60A	60	Missense	distal	-4	no	9.314	8.758	EPSD	COSMIC;CCLE	8.808	Loss
CMGC_CDK_CDK5_CDK5_ST	P01106	MYC	Q00535	CDK5	S64	P57T	57	Missense	distal	-7	no	9.314	9.304	EPSD	COSMIC;CCLE	8.808	Down-regulation
CMGC_CDK_CDK5_CDK5_ST	P01106	MYC	Q00535	CDK5	S64	P59S	59	Missense	distal	-5	no	9.314	9.336	EPSD	COSMIC;CCLE	8.808	Up-regulation
CMGC_CDK_CDK5_CDK5_ST	P01106	MYC	Q00535	CDK5	S64	S62F	62	Missense	proximal	-2	no	9.314	8.754	EPSD	COSMIC	8.808	Loss
CMGC_CDK_CDK5_CDK5_ST	P01106	MYC	Q00535	CDK5	S64	C70R	70	Missense	distal	6	no	9.314	9.337	EPSD	COSMIC	8.808	Up-regulation
CMGC_CDK_CDK5_CDK5_ST	P01106	MYC	Q00535	CDK5	S64	T58I	58	Missense	distal	-6	no	9.314	9.269	EPSD	COSMIC;CCLE	8.808	Down-regulation
CMGC_CDK_CDK5_CDK5_ST	P01106	MYC	Q00535	CDK5	S64	T58P	58	Missense	distal	-6	no	9.314	9.302	EPSD	COSMIC	8.808	Down-regulation
CMGC_CDK_CDK5_CDK5_ST	P01106	MYC	Q00535	CDK5	S64	S64R	64	Missense	central	0	yes	9.314	0.000	EPSD	COSMIC;CCLE	8.808	Loss
CMGC_CDK_CDK5_CDK5_ST	P01106	MYC	Q00535	CDK5	S64	P57L	57	Missense	distal	-7	no	9.314	9.262	EPSD	COSMIC;CCLE	8.808	Down-regulation
CMGC_CDK_CDK5_CDK5_ST	P01106	MYC	Q00535	CDK5	S64	P63S	63	Missense	proximal	-1	no	9.314	9.315	EPSD	COSMIC;CCLE	8.808	Up-regulation
CMGC_CDK_CDK5_CDK5_ST	P01106	MYC	Q00535	CDK5	S64	R66H	66	Missense	proximal	2	no	9.314	9.199	EPSD	COSMIC	8.808	Down-regulation
CMGC_CDK_CDK5_CDK5_ST	P01106	MYC	Q00535	CDK5	S64	P57F	57	Missense	distal	-7	no	9.314	9.234	EPSD	COSMIC	8.808	Down-regulation
CMGC_CDK_CDK5_CDK5_ST	P01106	MYC	Q00535	CDK5	S64	P59Q	59	Missense	distal	-5	no	9.314	9.255	EPSD	COSMIC;CCLE	8.808	Down-regulation
CMGC_CDK_CDK5_CDK5_ST	P01106	MYC	Q00535	CDK5	S64	P59T	59	Missense	distal	-5	no	9.314	9.310	EPSD	COSMIC	8.808	Down-regulation
CMGC_CDK_CDK5_CDK5_ST	P01106	MYC	Q00535	CDK5	S64	P60S	60	Missense	distal	-4	no	9.314	9.660	EPSD	COSMIC	8.808	Up-regulation
CMGC_CDK_CDK5_CDK5_ST	P01106	MYC	Q00535	CDK5	S64	S71L	71	Missense	distal	7	no	9.314	9.301	EPSD	COSMIC	8.808	Down-regulation
CMGC_CDK_CDK5_CDK5_ST	P01106	MYC	Q00535	CDK5	S64	P63A	63	Missense	proximal	-1	no	9.314	9.309	EPSD	COSMIC	8.808	Down-regulation
CMGC_CDK_CDK5_CDK5_ST	P01106	MYC	Q00535	CDK5	S64	S64N	64	Missense	central	0	yes	9.314	0.000	EPSD	COSMIC	8.808	Loss
CMGC_CDK_CDK5_CDK5_ST	P01106	MYC	Q00535	CDK5	S64	P60L	60	Missense	distal	-4	no	9.314	8.840	EPSD	COSMIC	8.808	Down-regulation
CMGC_CDK_CDK5_CDK5_ST	P01106	MYC	Q00535	CDK5	S64	P57A	57	Missense	distal	-7	no	9.314	9.264	EPSD	COSMIC	8.808	Down-regulation
CMGC_CDK_CDK5_CDK5_ST	P01106	MYC	Q00535	CDK5	S64	L69V	69	Missense	distal	5	no	9.314	9.461	EPSD	COSMIC	8.808	Up-regulation
CMGC_CDK_CDK5_CDK5_ST	P01106	MYC	Q00535	CDK5	S64	S67F	67	Missense	distal	3	no	9.314	8.136	EPSD	COSMIC	8.808	Loss
CMGC_CDK_CDK5_CDK5_ST	P01106	MYC	Q00535	CDK5	S64	S62A	62	Missense	proximal	-2	no	9.314	9.035	EPSD	COSMIC	8.808	Down-regulation
CMGC_CDK_CDK5_CDK5_ST	P01106	MYC	Q00535	CDK5	S64	P57R	57	Missense	distal	-7	no	9.314	9.318	EPSD	COSMIC	8.808	Up-regulation
CMGC_CDK_CDK5_CDK5_ST	P01106	MYC	Q00535	CDK5	S64	L69P	69	Missense	distal	5	no	9.314	9.486	EPSD	COSMIC	8.808	Up-regulation
CMGC_CDK_CDK5_CDK5_ST	P01106	MYC	Q00535	CDK5	S64	C70W	70	Missense	distal	6	no	9.314	9.320	EPSD	COSMIC	8.808	Up-regulation
CMGC_CDK_CDK5_CDK5_ST	P01106	MYC	Q00535	CDK5	S64	P60T	60	Missense	distal	-4	no	9.314	9.158	EPSD	COSMIC;CCLE	8.808	Down-regulation
CMGC_CDK_CDK5_CDK5_ST	P01106	MYC	Q00535	CDK5	S64	S71W	71	Missense	distal	7	no	9.314	9.305	EPSD	COSMIC	8.808	Down-regulation
CMGC_CDK_CDK5_CDK5_ST	P01106	MYC	Q00535	CDK5	S64	L69F	69	Missense	distal	5	no	9.314	9.259	EPSD	COSMIC	8.808	Down-regulation
CMGC_CDK_CDK5_CDK5_ST	P01106	MYC	Q00535	CDK5	S64	R65C	65	Missense	proximal	1	no	9.314	-2.413	EPSD	COSMIC	8.808	Loss
CMGC_CDK_CDK5_CDK5_ST	P01106	MYC	Q00535	CDK5	S71	C70R	70	Missense	proximal	-1	no	17.722	17.728	EPSD	COSMIC	8.808	Up-regulation
CMGC_CDK_CDK5_CDK5_ST	P01106	MYC	Q00535	CDK5	S71	S64R	64	Missense	distal	-7	no	17.722	17.721	EPSD	COSMIC;CCLE	8.808	Down-regulation
CMGC_CDK_CDK5_CDK5_ST	P01106	MYC	Q00535	CDK5	S71	R66H	66	Missense	distal	-5	no	17.722	17.549	EPSD	COSMIC	8.808	Down-regulation
CMGC_CDK_CDK5_CDK5_ST	P01106	MYC	Q00535	CDK5	S71	A76V	76	Missense	distal	5	no	17.722	17.819	EPSD	COSMIC	8.808	Up-regulation
CMGC_CDK_CDK5_CDK5_ST	P01106	MYC	Q00535	CDK5	S71	V77I	77	Missense	distal	6	no	17.722	17.718	EPSD	COSMIC;CCLE	8.808	Down-regulation
CMGC_CDK_CDK5_CDK5_ST	P01106	MYC	Q00535	CDK5	S71	S71L	71	Missense	central	0	yes	17.722	0.000	EPSD	COSMIC	8.808	Loss
CMGC_CDK_CDK5_CDK5_ST	P01106	MYC	Q00535	CDK5	S71	S64N	64	Missense	distal	-7	no	17.722	17.696	EPSD	COSMIC	8.808	Down-regulation
CMGC_CDK_CDK5_CDK5_ST	P01106	MYC	Q00535	CDK5	S71	Y74N	74	Missense	distal	3	no	17.722	18.295	EPSD	COSMIC;CCLE	8.808	Up-regulation
CMGC_CDK_CDK5_CDK5_ST	P01106	MYC	Q00535	CDK5	S71	L69V	69	Missense	proximal	-2	no	17.722	17.955	EPSD	COSMIC	8.808	Up-regulation
CMGC_CDK_CDK5_CDK5_ST	P01106	MYC	Q00535	CDK5	S71	V77G	77	Missense	distal	6	no	17.722	17.715	EPSD	COSMIC	8.808	Down-regulation
CMGC_CDK_CDK5_CDK5_ST	P01106	MYC	Q00535	CDK5	S71	Y74H	74	Missense	distal	3	no	17.722	18.889	EPSD	COSMIC	8.808	Up-regulation
CMGC_CDK_CDK5_CDK5_ST	P01106	MYC	Q00535	CDK5	S71	S67F	67	Missense	distal	-4	no	17.722	16.561	EPSD	COSMIC	8.808	Down-regulation
CMGC_CDK_CDK5_CDK5_ST	P01106	MYC	Q00535	CDK5	S71	V75I	75	Missense	distal	4	no	17.722	17.697	EPSD	COSMIC	8.808	Down-regulation
CMGC_CDK_CDK5_CDK5_ST	P01106	MYC	Q00535	CDK5	S71	L69P	69	Missense	proximal	-2	no	17.722	18.136	EPSD	COSMIC	8.808	Up-regulation
CMGC_CDK_CDK5_CDK5_ST	P01106	MYC	Q00535	CDK5	S71	C70W	70	Missense	proximal	-1	no	17.722	17.724	EPSD	COSMIC	8.808	Up-regulation
CMGC_CDK_CDK5_CDK5_ST	P01106	MYC	Q00535	CDK5	S71	S71W	71	Missense	central	0	yes	17.722	0.000	EPSD	COSMIC	8.808	Loss
CMGC_CDK_CDK5_CDK5_ST	P01106	MYC	Q00535	CDK5	S71	L69F	69	Missense	proximal	-2	no	17.722	17.479	EPSD	COSMIC	8.808	Down-regulation
CMGC_CDK_CDK5_CDK5_ST	P01106	MYC	Q00535	CDK5	S71	S73P	73	Missense	proximal	2	no	17.722	17.739	EPSD	COSMIC	8.808	Up-regulation
CMGC_CDK_CDK5_CDK5_ST	P01106	MYC	Q00535	CDK5	S71	S64T	64	Missense	distal	-7	no	17.722	17.707	EPSD	COSMIC	8.808	Down-regulation
CMGC_CDK_CDK5_CDK5_ST	P01106	MYC	Q00535	CDK5	S71	R65C	65	Missense	distal	-6	no	17.722	17.569	EPSD	COSMIC	8.808	Down-regulation
CMGC_CDK_CDK5_CDK5_ST	P01106	MYC	Q00535	CDK5	S71	P72F	72	Missense	proximal	1	no	17.722	-4.258	EPSD	COSMIC	8.808	Loss
CMGC_CDK_CDK5_CDK5_ST	P01106	MYC	Q00535	CDK5	S71	P72R	72	Missense	proximal	1	no	17.722	8.775	EPSD	COSMIC	8.808	Loss
CMGC_CDK_CDK5_CDK5_ST	P01106	MYC	Q00535	CDK5	T78	S81F	81	Missense	distal	3	no	16.878	15.701	EPSD	COSMIC;CCLE	8.808	Down-regulation
CMGC_CDK_CDK5_CDK5_ST	P01106	MYC	Q00535	CDK5	T78	R83Q	83	Missense	distal	5	no	16.878	16.753	EPSD	COSMIC	8.808	Down-regulation
CMGC_CDK_CDK5_CDK5_ST	P01106	MYC	Q00535	CDK5	T78	A76V	76	Missense	proximal	-2	no	16.878	17.074	EPSD	COSMIC	8.808	Up-regulation
CMGC_CDK_CDK5_CDK5_ST	P01106	MYC	Q00535	CDK5	T78	V77I	77	Missense	proximal	-1	no	16.878	16.877	EPSD	COSMIC;CCLE	8.808	Down-regulation
CMGC_CDK_CDK5_CDK5_ST	P01106	MYC	Q00535	CDK5	T78	S71L	71	Missense	distal	-7	no	16.878	16.822	EPSD	COSMIC	8.808	Down-regulation
CMGC_CDK_CDK5_CDK5_ST	P01106	MYC	Q00535	CDK5	T78	L82V	82	Missense	distal	4	no	16.878	16.942	EPSD	COSMIC	8.808	Up-regulation
CMGC_CDK_CDK5_CDK5_ST	P01106	MYC	Q00535	CDK5	T78	G84R	84	Missense	distal	6	no	16.878	16.895	EPSD	COSMIC	8.808	Up-regulation
CMGC_CDK_CDK5_CDK5_ST	P01106	MYC	Q00535	CDK5	T78	P79S	79	Missense	proximal	1	no	16.878	4.977	EPSD	COSMIC	8.808	Loss
CMGC_CDK_CDK5_CDK5_ST	P01106	MYC	Q00535	CDK5	T78	Y74N	74	Missense	distal	-4	no	16.878	17.346	EPSD	COSMIC;CCLE	8.808	Up-regulation
CMGC_CDK_CDK5_CDK5_ST	P01106	MYC	Q00535	CDK5	T78	F80L	80	Missense	proximal	2	no	16.878	16.940	EPSD	COSMIC	8.808	Up-regulation
CMGC_CDK_CDK5_CDK5_ST	P01106	MYC	Q00535	CDK5	T78	D85Y	85	Missense	distal	7	no	16.878	16.874	EPSD	COSMIC	8.808	Down-regulation
CMGC_CDK_CDK5_CDK5_ST	P01106	MYC	Q00535	CDK5	T78	V77G	77	Missense	proximal	-1	no	16.878	16.875	EPSD	COSMIC	8.808	Down-regulation
CMGC_CDK_CDK5_CDK5_ST	P01106	MYC	Q00535	CDK5	T78	S81C	81	Missense	distal	3	no	16.878	16.001	EPSD	COSMIC	8.808	Down-regulation
CMGC_CDK_CDK5_CDK5_ST	P01106	MYC	Q00535	CDK5	T78	Y74H	74	Missense	distal	-4	no	16.878	17.178	EPSD	COSMIC	8.808	Up-regulation
CMGC_CDK_CDK5_CDK5_ST	P01106	MYC	Q00535	CDK5	T78	V75I	75	Missense	distal	-3	no	16.878	16.863	EPSD	COSMIC	8.808	Down-regulation
CMGC_CDK_CDK5_CDK5_ST	P01106	MYC	Q00535	CDK5	T78	S71W	71	Missense	distal	-7	no	16.878	16.829	EPSD	COSMIC	8.808	Down-regulation
CMGC_CDK_CDK5_CDK5_ST	P01106	MYC	Q00535	CDK5	T78	L82H	82	Missense	distal	4	no	16.878	16.938	EPSD	COSMIC	8.808	Up-regulation
CMGC_CDK_CDK5_CDK5_ST	P01106	MYC	Q00535	CDK5	T78	S73P	73	Missense	distal	-5	no	16.878	16.856	EPSD	COSMIC	8.808	Down-regulation
CMGC_CDK_CDK5_CDK5_ST	P01106	MYC	Q00535	CDK5	T78	P72F	72	Missense	distal	-6	no	16.878	16.744	EPSD	COSMIC	8.808	Down-regulation
CMGC_CDK_CDK5_CDK5_ST	P01106	MYC	Q00535	CDK5	T78	P72R	72	Missense	distal	-6	no	16.878	16.924	EPSD	COSMIC	8.808	Up-regulation
CMGC_CDK_CDK5_CDK5_ST	P01106	MYC	Q00535	CDK5	S161	K157T	157	Missense	distal	-4	no	19.094	18.717	EPSD	COSMIC	8.808	Down-regulation
CMGC_CDK_CDK5_CDK5_ST	P01106	MYC	Q00535	CDK5	S161	A155S	155	Missense	distal	-6	no	19.094	19.208	EPSD	COSMIC	8.808	Up-regulation
CMGC_CDK_CDK5_CDK5_ST	P01106	MYC	Q00535	CDK5	S161	K157N	157	Missense	distal	-4	no	19.094	18.706	EPSD	COSMIC	8.808	Down-regulation
CMGC_CDK_CDK5_CDK5_ST	P01106	MYC	Q00535	CDK5	S161	A155T	155	Missense	distal	-6	no	19.094	19.180	EPSD	COSMIC	8.808	Up-regulation
CMGC_CDK_CDK5_CDK5_ST	P01106	MYC	Q00535	CDK5	S161	N163K	163	Missense	proximal	2	no	19.094	19.288	EPSD	COSMIC	8.808	Up-regulation
CMGC_CDK_CDK5_CDK5_ST	P01106	MYC	Q00535	CDK5	S161	P162R	162	Missense	proximal	1	no	19.094	10.146	EPSD	COSMIC	8.808	Down-regulation
CMGC_CDK_CDK5_CDK5_ST	P01106	MYC	Q00535	CDK5	S161	A154T	154	Missense	distal	-7	no	19.094	19.133	EPSD	COSMIC	8.808	Up-regulation
CMGC_CDK_CDK5_CDK5_ST	P01106	MYC	Q00535	CDK5	S161	S159N	159	Missense	proximal	-2	no	19.094	18.980	EPSD	COSMIC	8.808	Down-regulation
CMGC_CDK_CDK5_CDK5_ST	P01106	MYC	Q00535	CDK5	S161	A165S	165	Missense	distal	4	no	19.094	19.155	EPSD	COSMIC	8.808	Up-regulation
CMGC_CDK_CDK5_CDK5_ST	P01106	MYC	Q00535	CDK5	S161	A165T	165	Missense	distal	4	no	19.094	19.153	EPSD	COSMIC	8.808	Up-regulation
CMGC_CDK_CDK5_CDK5_ST	P01106	MYC	Q00535	CDK5	S161	S159T	159	Missense	proximal	-2	no	19.094	19.053	EPSD	COSMIC	8.808	Down-regulation
CMGC_CDK_CDK5_CDK5_ST	P01106	MYC	Q00535	CDK5	S161	D158G	158	Missense	distal	-3	no	19.094	19.093	EPSD	COSMIC	8.808	Down-regulation
CMGC_CDK_CDK5_CDK5_ST	P01106	MYC	Q00535	CDK5	S161	R166H	166	Missense	distal	5	no	19.094	18.990	EPSD	COSMIC	8.808	Down-regulation
CMGC_CDK_CDK5_CDK5_ST	P01106	MYC	Q00535	CDK5	S161	S161N	161	Missense	central	0	yes	19.094	0.000	EPSD	COSMIC	8.808	Loss
CMGC_CDK_CDK5_CDK5_ST	P01106	MYC	Q00535	CDK5	S161	R156G	156	Missense	distal	-5	no	19.094	18.842	EPSD	COSMIC	8.808	Down-regulation
CMGC_CDK_CDK5_CDK5_ST	P01106	MYC	Q00535	CDK5	S161	A154G	154	Missense	distal	-7	no	19.094	19.095	EPSD	COSMIC	8.808	Up-regulation
CMGC_CDK_CDK5_CDK5_ST	P01106	MYC	Q00535	CDK5	S161	S159R	159	Missense	proximal	-2	no	19.094	19.138	EPSD	COSMIC	8.808	Up-regulation
CMGC_CDK_CDK5_CDK5_ST	P01106	MYC	Q00535	CDK5	S161	A165D	165	Missense	distal	4	no	19.094	19.095	EPSD	COSMIC	8.808	Up-regulation
CMGC_CDK_CDK5_CDK5_ST	P01106	MYC	Q00535	CDK5	S172	S175R	175	Missense	distal	3	no	7.441	8.860	EPSD	COSMIC	8.808	Gain
CMGC_CDK_CDK5_CDK5_ST	P01106	MYC	Q00535	CDK5	S202	S203R	203	Missense	proximal	1	no	6.265	9.219	EPSD	COSMIC	8.808	Gain
CMGC_CDK_CDK5_CDK5_ST	P01106	MYC	Q00535	CDK5	S202	S203N	203	Missense	proximal	1	no	6.265	8.927	EPSD	COSMIC;CCLE	8.808	Gain
CMGC_CDK_CDK5_CDK5_ST	P01106	MYC	Q00535	CDK5	S204	P198S	198	Missense	distal	-6	no	18.353	18.392	EPSD	COSMIC	8.808	Up-regulation
CMGC_CDK_CDK5_CDK5_ST	P01106	MYC	Q00535	CDK5	S204	S203N	203	Missense	proximal	-1	no	18.353	18.351	EPSD	COSMIC;CCLE	8.808	Down-regulation
CMGC_CDK_CDK5_CDK5_ST	P01106	MYC	Q00535	CDK5	S204	Y197D	197	Missense	distal	-7	no	18.353	18.375	EPSD	COSMIC	8.808	Up-regulation
CMGC_CDK_CDK5_CDK5_ST	P01106	MYC	Q00535	CDK5	S204	S203T	203	Missense	proximal	-1	no	18.353	18.352	EPSD	COSMIC	8.808	Down-regulation
CMGC_CDK_CDK5_CDK5_ST	P01106	MYC	Q00535	CDK5	S204	S203I	203	Missense	proximal	-1	no	18.353	18.350	EPSD	COSMIC	8.808	Down-regulation
CMGC_CDK_CDK5_CDK5_ST	P01106	MYC	Q00535	CDK5	S204	Q211R	211	Missense	distal	7	no	18.353	18.359	EPSD	COSMIC	8.808	Up-regulation
CMGC_CDK_CDK5_CDK5_ST	P01106	MYC	Q00535	CDK5	S204	P205S	205	Missense	proximal	1	no	18.353	6.452	EPSD	COSMIC	8.808	Loss
CMGC_CDK_CDK5_CDK5_ST	P01106	MYC	Q00535	CDK5	S204	N200I	200	Missense	distal	-4	no	18.353	18.251	EPSD	COSMIC	8.808	Down-regulation
CMGC_CDK_CDK5_CDK5_ST	P01106	MYC	Q00535	CDK5	S204	S204A	204	Missense	central	0	yes	18.353	0.000	EPSD	COSMIC	8.808	Loss
CMGC_CDK_CDK5_CDK5_ST	P01106	MYC	Q00535	CDK5	S204	S202T	202	Missense	proximal	-2	no	18.353	18.313	EPSD	COSMIC	8.808	Down-regulation
CMGC_CDK_CDK5_CDK5_ST	P01106	MYC	Q00535	CDK5	S204	S207P	207	Missense	distal	3	no	18.353	18.373	EPSD	COSMIC	8.808	Up-regulation
CMGC_CDK_CDK5_CDK5_ST	P01106	MYC	Q00535	CDK5	S279	G280R	280	Missense	proximal	1	no	-3.004	9.465	EPSD	COSMIC	8.808	Gain
CMGC_CDK_CDK5_CDK5_ST	P01106	MYC	Q00535	CDK5	S281	S283F	283	Missense	proximal	2	no	18.435	18.225	EPSD	COSMIC	8.808	Down-regulation
CMGC_CDK_CDK5_CDK5_ST	P01106	MYC	Q00535	CDK5	S281	S277L	277	Missense	distal	-4	no	18.435	17.616	EPSD	COSMIC	8.808	Down-regulation
CMGC_CDK_CDK5_CDK5_ST	P01106	MYC	Q00535	CDK5	S281	S279C	279	Missense	proximal	-2	no	18.435	17.962	EPSD	COSMIC	8.808	Down-regulation
CMGC_CDK_CDK5_CDK5_ST	P01106	MYC	Q00535	CDK5	S281	S283Y	283	Missense	proximal	2	no	18.435	18.284	EPSD	COSMIC	8.808	Down-regulation
CMGC_CDK_CDK5_CDK5_ST	P01106	MYC	Q00535	CDK5	S281	P282A	282	Missense	proximal	1	no	18.435	7.409	EPSD	COSMIC	8.808	Loss
CMGC_CDK_CDK5_CDK5_ST	P01106	MYC	Q00535	CDK5	S281	G285E	285	Missense	distal	4	no	18.435	18.433	EPSD	COSMIC	8.808	Down-regulation
CMGC_CDK_CDK5_CDK5_ST	P01106	MYC	Q00535	CDK5	S281	G280R	280	Missense	proximal	-1	no	18.435	18.439	EPSD	COSMIC	8.808	Up-regulation
CMGC_CDK_CDK5_CDK5_ST	P01106	MYC	Q00535	CDK5	S281	G274D	274	Missense	distal	-7	no	18.435	18.443	EPSD	COSMIC	8.808	Up-regulation
CMGC_CDK_CDK5_CDK5_ST	P01106	MYC	Q00535	CDK5	S281	S281F	281	Missense	central	0	yes	18.435	0.000	EPSD	COSMIC	8.808	Loss
CMGC_CDK_CDK5_CDK5_ST	P01106	MYC	Q00535	CDK5	S293	S293C	293	Missense	central	0	yes	18.312	0.000	EPSD	COSMIC	8.808	Loss
CMGC_CDK_CDK5_CDK5_ST	P01106	MYC	Q00535	CDK5	S293	C300Y	300	Missense	distal	7	no	18.312	18.313	EPSD	COSMIC	8.808	Up-regulation
CMGC_CDK_CDK5_CDK5_ST	P01106	MYC	Q00535	CDK5	S293	P290T	290	Missense	distal	-3	no	18.312	18.305	EPSD	COSMIC	8.808	Down-regulation
CMGC_CDK_CDK5_CDK5_ST	P01106	MYC	Q00535	CDK5	S293	H287Q	287	Missense	distal	-6	no	18.312	18.320	EPSD	COSMIC	8.808	Up-regulation
CMGC_CDK_CDK5_CDK5_ST	P01106	MYC	Q00535	CDK5	S293	C300S	300	Missense	distal	7	no	18.312	18.326	EPSD	COSMIC	8.808	Up-regulation
CMGC_CDK_CDK5_CDK5_ST	P01106	MYC	Q00535	CDK5	S293	L295V	295	Missense	proximal	2	no	18.312	18.446	EPSD	COSMIC	8.808	Up-regulation
CMGC_CDK_CDK5_CDK5_ST	P01106	MYC	Q00535	CDK5	S293	P290H	290	Missense	distal	-3	no	18.312	18.289	EPSD	COSMIC	8.808	Down-regulation
CMGC_CDK_CDK5_CDK5_ST	P01106	MYC	Q00535	CDK5	S293	L297F	297	Missense	distal	4	no	18.312	18.283	EPSD	COSMIC	8.808	Down-regulation
CMGC_CDK_CDK5_CDK5_ST	P01106	MYC	Q00535	CDK5	S293	P290S	290	Missense	distal	-3	no	18.312	18.306	EPSD	COSMIC	8.808	Down-regulation
CMGC_CDK_CDK5_CDK5_ST	P01106	MYC	Q00535	CDK5	S293	S293R	293	Missense	central	0	yes	18.312	0.000	EPSD	COSMIC	8.808	Loss
CMGC_CDK_CDK5_CDK5_ST	P01106	MYC	Q00535	CDK5	S293	V296F	296	Missense	distal	3	no	18.312	17.107	EPSD	COSMIC	8.808	Down-regulation
CMGC_CDK_CDK5_CDK5_ST	P01106	MYC	Q00535	CDK5	S314	D318N	318	Missense	distal	4	no	8.804	8.834	EPSD	COSMIC	8.808	Gain
CMGC_CDK_CDK5_CDK5_ST	P01106	MYC	Q00535	CDK5	S314	A321T	321	Missense	distal	7	no	8.804	8.812	EPSD	COSMIC	8.808	Gain
CMGC_CDK_CDK5_CDK5_ST	P01106	MYC	Q00535	CDK5	S314	A311G	311	Missense	distal	-3	no	8.804	8.810	EPSD	COSMIC	8.808	Gain
CMGC_CDK_CDK5_CDK5_ST	P01106	MYC	Q00535	CDK5	S314	A310T	310	Missense	distal	-4	no	8.804	9.203	EPSD	COSMIC	8.808	Gain
CMGC_CDK_CDK5_CDK5_ST	P01106	MYC	Q00535	CDK5	S314	A321V	321	Missense	distal	7	no	8.804	8.811	EPSD	COSMIC	8.808	Gain
CMGC_CDK_CDK5_CDK5_ST	P01106	MYC	Q00535	CDK5	S337	V330L	330	Missense	distal	-7	no	9.652	9.614	EPSD	COSMIC	8.808	Down-regulation
CMGC_CDK_CDK5_CDK5_ST	P01106	MYC	Q00535	CDK5	S337	I336V	336	Missense	proximal	-1	no	9.652	9.653	EPSD	COSMIC	8.808	Up-regulation
CMGC_CDK_CDK5_CDK5_ST	P01106	MYC	Q00535	CDK5	S337	L333P	333	Missense	distal	-4	no	9.652	10.125	EPSD	COSMIC	8.808	Up-regulation
CMGC_CDK_CDK5_CDK5_ST	P01106	MYC	Q00535	CDK5	S337	L333V	333	Missense	distal	-4	no	9.652	9.989	EPSD	COSMIC	8.808	Up-regulation
CMGC_CDK_CDK5_CDK5_ST	P01106	MYC	Q00535	CDK5	S344	S347F	347	Missense	distal	3	no	17.132	15.955	EPSD	COSMIC	8.808	Down-regulation
CMGC_CDK_CDK5_CDK5_ST	P01106	MYC	Q00535	CDK5	S344	E351K	351	Missense	distal	7	no	17.132	17.148	EPSD	COSMIC	8.808	Up-regulation
CMGC_CDK_CDK5_CDK5_ST	P01106	MYC	Q00535	CDK5	S344	S337T	337	Missense	distal	-7	no	17.132	17.118	EPSD	COSMIC	8.808	Down-regulation
CMGC_CDK_CDK5_CDK5_ST	P01106	MYC	Q00535	CDK5	S348	E351K	351	Missense	distal	3	no	7.299	9.585	EPSD	COSMIC	8.808	Gain
CMGC_CDK_CDK5_CDK5_ST	Q14195	DPYSL3	Q00535	CDK5	S308	P314L	314	Missense	distal	6	no	18.614	18.601	EPSD	COSMIC	8.808	Down-regulation
CMGC_CDK_CDK5_CDK5_ST	Q14195	DPYSL3	Q00535	CDK5	S308	T312N	312	Missense	distal	4	no	18.614	18.586	EPSD	COSMIC	8.808	Down-regulation
CMGC_CDK_CDK5_CDK5_ST	Q14195	DPYSL3	Q00535	CDK5	S308	D315Y	315	Missense	distal	7	no	18.614	18.610	EPSD	COSMIC	8.808	Down-regulation
CMGC_CDK_CDK5_CDK5_ST	Q14195	DPYSL3	Q00535	CDK5	S472	V478A	478	Missense	distal	6	no	17.452	17.443	EPSD	COSMIC	8.808	Down-regulation
CMGC_CDK_CDK5_CDK5_ST	Q14195	DPYSL3	Q00535	CDK5	S472	R467C	467	Missense	distal	-5	no	17.452	17.098	EPSD	COSMIC;CCLE	8.808	Down-regulation
CMGC_CDK_CDK5_CDK5_ST	Q14195	DPYSL3	Q00535	CDK5	S472	D476N	476	Missense	distal	4	no	17.452	17.482	EPSD	COSMIC	8.808	Up-regulation
CMGC_CDK_CDK5_CDK5_ST	Q14195	DPYSL3	Q00535	CDK5	S472	P473L	473	Missense	proximal	1	no	17.452	5.503	EPSD	COSMIC	8.808	Loss
CMGC_CDK_CDK5_CDK5_ST	Q14195	DPYSL3	Q00535	CDK5	T509	A516T	516	Missense	distal	7	no	17.034	17.042	EPSD	COSMIC;GDSC;CCLE	8.808	Up-regulation
CMGC_CDK_CDK5_CDK5_ST	Q14195	DPYSL3	Q00535	CDK5	T514	R520Q	520	Missense	distal	6	no	17.300	17.289	EPSD	COSMIC	8.808	Down-regulation
CMGC_CDK_CDK5_CDK5_ST	Q14195	DPYSL3	Q00535	CDK5	T514	A516T	516	Missense	proximal	2	no	17.300	17.419	EPSD	COSMIC;GDSC;CCLE	8.808	Up-regulation
CMGC_CDK_CDK5_CDK5_ST	Q14195	DPYSL3	Q00535	CDK5	S522	R525Q	525	Missense	distal	3	no	20.102	18.299	PhosphoSitePlus	COSMIC;GDSC;CCLE	8.808	Down-regulation
CMGC_CDK_CDK5_CDK5_ST	Q14195	DPYSL3	Q00535	CDK5	S522	R520Q	520	Missense	proximal	-2	no	20.102	19.965	PhosphoSitePlus	COSMIC	8.808	Down-regulation
CMGC_CDK_CDK5_CDK5_ST	Q14195	DPYSL3	Q00535	CDK5	S522	A516T	516	Missense	distal	-6	no	20.102	20.188	PhosphoSitePlus	COSMIC;GDSC;CCLE	8.808	Up-regulation
CMGC_CDK_CDK5_CDK5_ST	Q14195	DPYSL3	Q00535	CDK5	S522	P529H	529	Missense	distal	7	no	20.102	20.097	PhosphoSitePlus	COSMIC	8.808	Down-regulation
CMGC_CDK_CDK5_CDK5_ST	O60260	PRKN	Q00535	CDK5	S131	K129N	129	Missense	proximal	-2	no	17.941	17.758	PhosphoSitePlus	COSMIC	8.808	Down-regulation
CMGC_CDK_CDK5_CDK5_ST	O60260	PRKN	Q00535	CDK5	S131	D126E	126	Missense	distal	-5	no	17.941	17.932	PhosphoSitePlus	COSMIC	8.808	Down-regulation
CMGC_CDK_CDK5_CDK5_ST	O60260	PRKN	Q00535	CDK5	S131	P132T	132	Missense	proximal	1	no	17.941	7.454	PhosphoSitePlus	COSMIC	8.808	Loss
CMGC_CDK_CDK5_CDK5_ST	O60260	PRKN	Q00535	CDK5	S131	D130N	130	Missense	proximal	-1	no	17.941	17.943	PhosphoSitePlus	COSMIC	8.808	Up-regulation
CMGC_CDK_CDK5_CDK5_ST	O60260	PRKN	Q00535	CDK5	S131	P132Q	132	Missense	proximal	1	no	17.941	8.966	PhosphoSitePlus	COSMIC	8.808	Down-regulation
CMGC_CDK_CDK5_CDK5_ST	O60260	PRKN	Q00535	CDK5	S131	A138P	138	Missense	distal	7	no	17.941	17.952	PhosphoSitePlus	COSMIC	8.808	Up-regulation
CMGC_CDK_CDK5_CDK5_ST	O60260	PRKN	Q00535	CDK5	S131	A138E	138	Missense	distal	7	no	17.941	17.943	PhosphoSitePlus	COSMIC	8.808	Up-regulation
CMGC_CDK_CDK5_CDK5_ST	O60260	PRKN	Q00535	CDK5	S131	K129M	129	Missense	proximal	-2	no	17.941	17.397	PhosphoSitePlus	COSMIC	8.808	Down-regulation
CMGC_CDK_CDK5_CDK5_ST	O60260	PRKN	Q00535	CDK5	S131	D130H	130	Missense	proximal	-1	no	17.941	17.943	PhosphoSitePlus	COSMIC	8.808	Up-regulation
CMGC_CDK_CDK5_CDK5_ST	O60260	PRKN	Q00535	CDK5	S131	R128K	128	Missense	distal	-3	no	17.941	17.961	PhosphoSitePlus	COSMIC	8.808	Up-regulation
CMGC_CDK_CDK5_CDK5_ST	O60260	PRKN	Q00535	CDK5	S131	T125S	125	Missense	distal	-6	no	17.941	17.969	PhosphoSitePlus	COSMIC	8.808	Up-regulation
CMGC_CDK_CDK5_CDK5_ST	O60260	PRKN	Q00535	CDK5	S131	T125A	125	Missense	distal	-6	no	17.941	17.855	PhosphoSitePlus	COSMIC	8.808	Down-regulation
CMGC_CDK_CDK5_CDK5_ST	O60260	PRKN	Q00535	CDK5	S131	G135A	135	Missense	distal	4	no	17.941	17.930	PhosphoSitePlus	COSMIC	8.808	Down-regulation
CMGC_CDK_CDK5_CDK5_ST	O60260	PRKN	Q00535	CDK5	S131	P132H	132	Missense	proximal	1	no	17.941	-0.571	PhosphoSitePlus	COSMIC	8.808	Loss
CMGC_CDK_CDK5_CDK5_ST	O60260	PRKN	Q00535	CDK5	S131	D126H	126	Missense	distal	-5	no	17.941	18.015	PhosphoSitePlus	COSMIC	8.808	Up-regulation
CMGC_CDK_CDK5_CDK5_ST	O60260	PRKN	Q00535	CDK5	S131	P132S	132	Missense	proximal	1	no	17.941	6.040	PhosphoSitePlus	COSMIC	8.808	Loss
CMGC_CDK_CDK5_CDK5_ST	O60260	PRKN	Q00535	CDK5	S136	K129N	129	Missense	distal	-7	no	18.083	18.040	EPSD	COSMIC	8.808	Down-regulation
CMGC_CDK_CDK5_CDK5_ST	O60260	PRKN	Q00535	CDK5	S136	S141L	141	Missense	distal	5	no	18.083	17.898	EPSD	COSMIC	8.808	Down-regulation
CMGC_CDK_CDK5_CDK5_ST	O60260	PRKN	Q00535	CDK5	S136	P132T	132	Missense	distal	-4	no	18.083	17.927	EPSD	COSMIC	8.808	Down-regulation
CMGC_CDK_CDK5_CDK5_ST	O60260	PRKN	Q00535	CDK5	S136	D130N	130	Missense	distal	-6	no	18.083	18.121	EPSD	COSMIC	8.808	Up-regulation
CMGC_CDK_CDK5_CDK5_ST	O60260	PRKN	Q00535	CDK5	S136	P132Q	132	Missense	distal	-4	no	18.083	17.958	EPSD	COSMIC	8.808	Down-regulation
CMGC_CDK_CDK5_CDK5_ST	O60260	PRKN	Q00535	CDK5	S136	A138P	138	Missense	proximal	2	no	18.083	18.195	EPSD	COSMIC	8.808	Up-regulation
CMGC_CDK_CDK5_CDK5_ST	O60260	PRKN	Q00535	CDK5	S136	A138E	138	Missense	proximal	2	no	18.083	18.075	EPSD	COSMIC	8.808	Down-regulation
CMGC_CDK_CDK5_CDK5_ST	O60260	PRKN	Q00535	CDK5	S136	K129M	129	Missense	distal	-7	no	18.083	17.993	EPSD	COSMIC	8.808	Down-regulation
CMGC_CDK_CDK5_CDK5_ST	O60260	PRKN	Q00535	CDK5	S136	D130H	130	Missense	distal	-6	no	18.083	18.121	EPSD	COSMIC	8.808	Up-regulation
CMGC_CDK_CDK5_CDK5_ST	O60260	PRKN	Q00535	CDK5	S136	G135A	135	Missense	proximal	-1	no	18.083	18.082	EPSD	COSMIC	8.808	Down-regulation
CMGC_CDK_CDK5_CDK5_ST	O60260	PRKN	Q00535	CDK5	S136	P132H	132	Missense	distal	-4	no	18.083	17.748	EPSD	COSMIC	8.808	Down-regulation
CMGC_CDK_CDK5_CDK5_ST	O60260	PRKN	Q00535	CDK5	S136	P132S	132	Missense	distal	-4	no	18.083	18.429	EPSD	COSMIC	8.808	Up-regulation
CMGC_CDK_CDK5_CDK5_ST	O60260	PRKN	Q00535	CDK5	S198	R191W	191	Missense	distal	-7	no	16.032	15.982	EPSD	COSMIC;GDSC	8.808	Down-regulation
CMGC_CDK_CDK5_CDK5_ST	O60260	PRKN	Q00535	CDK5	S198	C196S	196	Missense	proximal	-2	no	16.032	16.504	EPSD	COSMIC	8.808	Up-regulation
CMGC_CDK_CDK5_CDK5_ST	O60260	PRKN	Q00535	CDK5	S198	T204S	204	Missense	distal	6	no	16.032	16.031	EPSD	COSMIC	8.808	Down-regulation
CMGC_CDK_CDK5_CDK5_ST	O60260	PRKN	Q00535	CDK5	S198	G203V	203	Missense	distal	5	no	16.032	16.098	EPSD	COSMIC	8.808	Up-regulation
CMGC_CDK_CDK5_CDK5_ST	O60260	PRKN	Q00535	CDK5	S198	R191Q	191	Missense	distal	-7	no	16.032	16.012	EPSD	COSMIC	8.808	Down-regulation
CMGC_CDK_CDK5_CDK5_ST	O60260	PRKN	Q00535	CDK5	S198	G194I	194	Missense	distal	-4	no	16.032	16.257	EPSD	COSMIC	8.808	Up-regulation
CMGC_CDK_CDK5_CDK5_ST	O60260	PRKN	Q00535	CDK5	S198	C196Y	196	Missense	proximal	-2	no	16.032	16.075	EPSD	COSMIC	8.808	Up-regulation
CMGC_CDK_CDK5_CDK5_ST	O60260	PRKN	Q00535	CDK5	S198	H200P	200	Missense	proximal	2	no	16.032	16.065	EPSD	COSMIC	8.808	Up-regulation
CMGC_CDK_CDK5_CDK5_ST	O60260	PRKN	Q00535	CDK5	S198	E195K	195	Missense	distal	-3	no	16.032	16.104	EPSD	COSMIC	8.808	Up-regulation
CMGC_CDK_CDK5_CDK5_ST	O60260	PRKN	Q00535	CDK5	S198	G194E	194	Missense	distal	-4	no	16.032	16.245	EPSD	COSMIC	8.808	Up-regulation
CMGC_CDK_CDK5_CDK5_ST	O60260	PRKN	Q00535	CDK5	S246	T240M	240	Missense	distal	-6	no	16.850	16.729	EPSD	COSMIC	8.808	Down-regulation
CMGC_CDK_CDK5_CDK5_ST	O60260	PRKN	Q00535	CDK5	S246	D243N	243	Missense	distal	-3	no	16.850	16.872	EPSD	COSMIC	8.808	Up-regulation
CMGC_CDK_CDK5_CDK5_ST	O60260	PRKN	Q00535	CDK5	S246	S246R	246	Missense	central	0	yes	16.850	0.000	EPSD	COSMIC	8.808	Loss
CMGC_CDK_CDK5_CDK5_ST	O60260	PRKN	Q00535	CDK5	S246	Q252R	252	Missense	distal	6	no	16.850	16.861	EPSD	COSMIC	8.808	Up-regulation
CMGC_CDK_CDK5_CDK5_ST	O60260	PRKN	Q00535	CDK5	S246	V244I	244	Missense	proximal	-2	no	16.850	16.709	EPSD	COSMIC	8.808	Down-regulation
CMGC_CDK_CDK5_CDK5_ST	O60260	PRKN	Q00535	CDK5	S246	T242A	242	Missense	distal	-4	no	16.850	16.450	EPSD	COSMIC	8.808	Down-regulation
CMGC_CDK_CDK5_CDK5_ST	P09874	PARP1	Q00535	CDK5	S41	V39M	39	Missense	proximal	-2	no	16.170	15.778	EPSD	COSMIC	8.808	Down-regulation
CMGC_CDK_CDK5_CDK5_ST	P09874	PARP1	Q00535	CDK5	S179	R173Q	173	Missense	distal	-6	no	10.289	10.231	EPSD	COSMIC	8.808	Down-regulation
CMGC_CDK_CDK5_CDK5_ST	P09874	PARP1	Q00535	CDK5	S179	L186F	186	Missense	distal	7	no	10.289	10.284	EPSD	COSMIC	8.808	Down-regulation
CMGC_CDK_CDK5_CDK5_ST	P09874	PARP1	Q00535	CDK5	S179	R173W	173	Missense	distal	-6	no	10.289	10.182	EPSD	COSMIC	8.808	Down-regulation
CMGC_CDK_CDK5_CDK5_ST	P09874	PARP1	Q00535	CDK5	S179	G183S	183	Missense	distal	4	no	10.289	10.340	EPSD	COSMIC	8.808	Up-regulation
CMGC_CDK_CDK5_CDK5_ST	P09874	PARP1	Q00535	CDK5	S179	F172V	172	Missense	distal	-7	no	10.289	10.355	EPSD	COSMIC	8.808	Up-regulation
CMGC_CDK_CDK5_CDK5_ST	P09874	PARP1	Q00535	CDK5	T327	V334E	334	Missense	distal	7	no	18.538	18.532	EPSD	COSMIC	8.808	Down-regulation
CMGC_CDK_CDK5_CDK5_ST	P09874	PARP1	Q00535	CDK5	T335	R340L	340	Missense	distal	5	no	17.237	16.989	EPSD	COSMIC	8.808	Down-regulation
CMGC_CDK_CDK5_CDK5_ST	P09874	PARP1	Q00535	CDK5	T335	V334E	334	Missense	proximal	-1	no	17.237	17.235	EPSD	COSMIC	8.808	Down-regulation
CMGC_CDK_CDK5_CDK5_ST	P09874	PARP1	Q00535	CDK5	T368	P370S	370	Missense	proximal	2	no	17.579	17.561	EPSD	COSMIC	8.808	Down-regulation
CMGC_CDK_CDK5_CDK5_ST	P09874	PARP1	Q00535	CDK5	T368	T361N	361	Missense	distal	-7	no	17.579	17.568	EPSD	COSMIC	8.808	Down-regulation
CMGC_CDK_CDK5_CDK5_ST	P09874	PARP1	Q00535	CDK5	T368	S372F	372	Missense	distal	4	no	17.579	17.467	EPSD	COSMIC	8.808	Down-regulation
CMGC_CDK_CDK5_CDK5_ST	P09874	PARP1	Q00535	CDK5	T368	S364F	364	Missense	distal	-4	no	17.579	16.418	EPSD	COSMIC	8.808	Down-regulation
CMGC_CDK_CDK5_CDK5_ST	P09874	PARP1	Q00535	CDK5	S391	A384T	384	Missense	distal	-7	no	10.337	10.376	EPSD	COSMIC	8.808	Up-regulation
CMGC_CDK_CDK5_CDK5_ST	P09874	PARP1	Q00535	CDK5	S391	L398F	398	Missense	distal	7	no	10.337	10.332	EPSD	COSMIC	8.808	Down-regulation
CMGC_CDK_CDK5_CDK5_ST	P09874	PARP1	Q00535	CDK5	S391	I395V	395	Missense	distal	4	no	10.337	10.361	EPSD	COSMIC	8.808	Up-regulation
CMGC_CDK_CDK5_CDK5_ST	P09874	PARP1	Q00535	CDK5	S431	I430M	430	Missense	proximal	-1	no	9.235	9.231	EPSD	COSMIC	8.808	Down-regulation
CMGC_CDK_CDK5_CDK5_ST	P09874	PARP1	Q00535	CDK5	S479	S479F	479	Missense	central	0	yes	17.232	0.000	EPSD	COSMIC	8.808	Loss
CMGC_CDK_CDK5_CDK5_ST	P09874	PARP1	Q00535	CDK5	S479	H476N	476	Missense	distal	-3	no	17.232	17.231	EPSD	COSMIC;CCLE	8.808	Down-regulation
CMGC_CDK_CDK5_CDK5_ST	P09874	PARP1	Q00535	CDK5	S479	W481C	481	Missense	proximal	2	no	17.232	17.157	EPSD	COSMIC	8.808	Down-regulation
CMGC_CDK_CDK5_CDK5_ST	P09874	PARP1	Q00535	CDK5	S479	L474S	474	Missense	distal	-5	no	17.232	17.452	EPSD	COSMIC	8.808	Up-regulation
CMGC_CDK_CDK5_CDK5_ST	Q16555	DPYSL2	Q00535	CDK5	S304	A298T	298	Missense	distal	-6	no	16.977	17.063	EPSD	COSMIC	8.808	Up-regulation
CMGC_CDK_CDK5_CDK5_ST	Q16555	DPYSL2	Q00535	CDK5	S304	P305L	305	Missense	proximal	1	no	16.977	5.027	EPSD	COSMIC	8.808	Loss
CMGC_CDK_CDK5_CDK5_ST	Q16555	DPYSL2	Q00535	CDK5	S304	P305T	305	Missense	proximal	1	no	16.977	6.490	EPSD	COSMIC	8.808	Loss
CMGC_CDK_CDK5_CDK5_ST	Q16555	DPYSL2	Q00535	CDK5	S304	V302F	302	Missense	proximal	-2	no	16.977	16.500	EPSD	COSMIC	8.808	Down-regulation
CMGC_CDK_CDK5_CDK5_ST	Q16555	DPYSL2	Q00535	CDK5	S304	L307S	307	Missense	distal	3	no	16.977	18.029	EPSD	COSMIC	8.808	Up-regulation
CMGC_CDK_CDK5_CDK5_ST	Q16555	DPYSL2	Q00535	CDK5	S308	P305L	305	Missense	distal	-3	no	18.358	18.297	EPSD	COSMIC	8.808	Down-regulation
CMGC_CDK_CDK5_CDK5_ST	Q16555	DPYSL2	Q00535	CDK5	S308	P305T	305	Missense	distal	-3	no	18.358	18.350	EPSD	COSMIC	8.808	Down-regulation
CMGC_CDK_CDK5_CDK5_ST	Q16555	DPYSL2	Q00535	CDK5	S308	V302F	302	Missense	distal	-6	no	18.358	18.229	EPSD	COSMIC	8.808	Down-regulation
CMGC_CDK_CDK5_CDK5_ST	Q16555	DPYSL2	Q00535	CDK5	S308	L307S	307	Missense	proximal	-1	no	18.358	18.364	EPSD	COSMIC	8.808	Up-regulation
CMGC_CDK_CDK5_CDK5_ST	Q16555	DPYSL2	Q00535	CDK5	S442	G436C	436	Missense	distal	-6	no	16.852	16.801	EPSD	COSMIC;GDSC;CCLE	8.808	Down-regulation
CMGC_CDK_CDK5_CDK5_ST	Q16555	DPYSL2	Q00535	CDK5	S442	V446I	446	Missense	distal	4	no	16.852	16.828	EPSD	COSMIC	8.808	Down-regulation
CMGC_CDK_CDK5_CDK5_ST	Q16555	DPYSL2	Q00535	CDK5	S442	S448N	448	Missense	distal	6	no	16.852	16.847	EPSD	COSMIC;GDSC;CCLE	8.808	Down-regulation
CMGC_CDK_CDK5_CDK5_ST	Q16555	DPYSL2	Q00535	CDK5	S448	V446I	446	Missense	proximal	-2	no	9.617	9.476	EPSD	COSMIC	8.808	Down-regulation
CMGC_CDK_CDK5_CDK5_ST	Q16555	DPYSL2	Q00535	CDK5	S448	S448N	448	Missense	central	0	yes	9.617	0.000	EPSD	COSMIC;GDSC;CCLE	8.808	Loss
CMGC_CDK_CDK5_CDK5_ST	Q16555	DPYSL2	Q00535	CDK5	T509	V506A	506	Missense	distal	-3	no	17.252	17.214	EPSD	COSMIC	8.808	Down-regulation
CMGC_CDK_CDK5_CDK5_ST	P27695	APEX1	Q00535	CDK5	S54	P48L	48	Missense	distal	-6	no	17.662	17.578	EPSD	COSMIC;GDSC;CCLE	8.808	Down-regulation
CMGC_CDK_CDK5_CDK5_ST	P27695	APEX1	Q00535	CDK5	S54	D47A	47	Missense	distal	-7	no	17.662	17.651	EPSD	COSMIC	8.808	Down-regulation
CMGC_CDK_CDK5_CDK5_ST	P27695	APEX1	Q00535	CDK5	T233	T233M	233	Missense	central	0	yes	17.263	0.000	PhosphoSitePlus	COSMIC	8.808	Loss
CMGC_CDK_CDK5_CDK5_ST	P27695	APEX1	Q00535	CDK5	T260	A263V	263	Missense	distal	3	no	17.060	17.312	EPSD	COSMIC	8.808	Up-regulation
CMGC_CDK_CDK5_CDK5_ST	P06400	RB1	Q00535	CDK5	T5	P6S	6	Missense	proximal	1	no	19.240	7.339	EPSD	COSMIC	8.808	Loss
CMGC_CDK_CDK5_CDK5_ST	P06400	RB1	Q00535	CDK5	T5	P2S	2	Missense	distal	-3	no	19.240	19.235	EPSD	COSMIC	8.808	Down-regulation
CMGC_CDK_CDK5_CDK5_ST	P06400	RB1	Q00535	CDK5	T5	T5N	5	Missense	central	0	yes	19.240	0.000	EPSD	COSMIC	8.808	Loss
CMGC_CDK_CDK5_CDK5_ST	P06400	RB1	Q00535	CDK5	T5	R7Q	7	Missense	proximal	2	no	19.240	19.101	EPSD	COSMIC	8.808	Down-regulation
CMGC_CDK_CDK5_CDK5_ST	P06400	RB1	Q00535	CDK5	S230	K228R	228	Missense	proximal	-2	no	15.282	15.256	EPSD	COSMIC;GDSC;CCLE	8.808	Down-regulation
CMGC_CDK_CDK5_CDK5_ST	P06400	RB1	Q00535	CDK5	S230	I227N	227	Missense	distal	-3	no	15.282	15.288	EPSD	COSMIC	8.808	Up-regulation
CMGC_CDK_CDK5_CDK5_ST	P06400	RB1	Q00535	CDK5	S230	P232L	232	Missense	proximal	2	no	15.282	15.116	EPSD	COSMIC	8.808	Down-regulation
CMGC_CDK_CDK5_CDK5_ST	P06400	RB1	Q00535	CDK5	S249	V243A	243	Missense	distal	-6	no	19.717	19.648	EPSD	COSMIC	8.808	Down-regulation
CMGC_CDK_CDK5_CDK5_ST	P06400	RB1	Q00535	CDK5	S249	P250S	250	Missense	proximal	1	no	19.717	7.816	EPSD	COSMIC	8.808	Loss
CMGC_CDK_CDK5_CDK5_ST	P06400	RB1	Q00535	CDK5	T252	Q257R	257	Missense	distal	5	no	18.798	18.923	EPSD	COSMIC	8.808	Up-regulation
CMGC_CDK_CDK5_CDK5_ST	P06400	RB1	Q00535	CDK5	T252	P250S	250	Missense	proximal	-2	no	18.798	18.699	EPSD	COSMIC	8.808	Down-regulation
CMGC_CDK_CDK5_CDK5_ST	P06400	RB1	Q00535	CDK5	T356	E352K	352	Missense	distal	-4	no	18.896	19.398	EPSD	COSMIC	8.808	Up-regulation
CMGC_CDK_CDK5_CDK5_ST	P06400	RB1	Q00535	CDK5	T356	R358Q	358	Missense	proximal	2	no	18.896	18.756	EPSD	COSMIC;CCLE	8.808	Down-regulation
CMGC_CDK_CDK5_CDK5_ST	P06400	RB1	Q00535	CDK5	T356	N361Y	361	Missense	distal	5	no	18.896	18.782	EPSD	COSMIC	8.808	Down-regulation
CMGC_CDK_CDK5_CDK5_ST	P06400	RB1	Q00535	CDK5	T373	P370S	370	Missense	distal	-3	no	18.227	18.222	EPSD	COSMIC	8.808	Down-regulation
CMGC_CDK_CDK5_CDK5_ST	P06400	RB1	Q00535	CDK5	T373	P374L	374	Missense	proximal	1	no	18.227	6.277	EPSD	COSMIC	8.808	Loss
CMGC_CDK_CDK5_CDK5_ST	P06400	RB1	Q00535	CDK5	T373	N367D	367	Missense	distal	-6	no	18.227	18.188	EPSD	COSMIC	8.808	Down-regulation
CMGC_CDK_CDK5_CDK5_ST	P06400	RB1	Q00535	CDK5	T373	P370L	370	Missense	distal	-3	no	18.227	18.166	EPSD	COSMIC	8.808	Down-regulation
CMGC_CDK_CDK5_CDK5_ST	P06400	RB1	Q00535	CDK5	S567	W563C	563	Missense	distal	-4	no	16.330	16.115	EPSD	COSMIC	8.808	Down-regulation
CMGC_CDK_CDK5_CDK5_ST	P06400	RB1	Q00535	CDK5	S567	S560P	560	Missense	distal	-7	no	16.330	16.325	EPSD	COSMIC	8.808	Down-regulation
CMGC_CDK_CDK5_CDK5_ST	P06400	RB1	Q00535	CDK5	S567	L564V	564	Missense	distal	-3	no	16.330	16.376	EPSD	COSMIC	8.808	Up-regulation
CMGC_CDK_CDK5_CDK5_ST	P06400	RB1	Q00535	CDK5	S567	L572F	572	Missense	distal	5	no	16.330	16.276	EPSD	COSMIC	8.808	Down-regulation
CMGC_CDK_CDK5_CDK5_ST	P06400	RB1	Q00535	CDK5	S608	R611S	611	Missense	distal	3	no	18.641	17.223	EPSD	COSMIC	8.808	Down-regulation
CMGC_CDK_CDK5_CDK5_ST	P06400	RB1	Q00535	CDK5	S608	S612P	612	Missense	distal	4	no	18.641	18.640	EPSD	COSMIC	8.808	Down-regulation
CMGC_CDK_CDK5_CDK5_ST	P06400	RB1	Q00535	CDK5	S608	Y606C	606	Missense	proximal	-2	no	18.641	18.598	EPSD	COSMIC	8.808	Down-regulation
CMGC_CDK_CDK5_CDK5_ST	P06400	RB1	Q00535	CDK5	S608	P609S	609	Missense	proximal	1	no	18.641	6.740	EPSD	COSMIC	8.808	Loss
CMGC_CDK_CDK5_CDK5_ST	P06400	RB1	Q00535	CDK5	S608	M605T	605	Missense	distal	-3	no	18.641	18.704	EPSD	COSMIC	8.808	Up-regulation
CMGC_CDK_CDK5_CDK5_ST	P06400	RB1	Q00535	CDK5	S608	L607V	607	Missense	proximal	-1	no	18.641	18.645	EPSD	COSMIC	8.808	Up-regulation
CMGC_CDK_CDK5_CDK5_ST	P06400	RB1	Q00535	CDK5	S608	L607I	607	Missense	proximal	-1	no	18.641	18.644	EPSD	COSMIC	8.808	Up-regulation
CMGC_CDK_CDK5_CDK5_ST	P06400	RB1	Q00535	CDK5	S612	R611S	611	Missense	proximal	-1	no	20.210	20.211	EPSD	COSMIC	8.808	Up-regulation
CMGC_CDK_CDK5_CDK5_ST	P06400	RB1	Q00535	CDK5	S612	S612P	612	Missense	central	0	yes	20.210	0.000	EPSD	COSMIC	8.808	Loss
CMGC_CDK_CDK5_CDK5_ST	P06400	RB1	Q00535	CDK5	S612	Y606C	606	Missense	distal	-6	no	20.210	20.198	EPSD	COSMIC	8.808	Down-regulation
CMGC_CDK_CDK5_CDK5_ST	P06400	RB1	Q00535	CDK5	S612	P609S	609	Missense	distal	-3	no	20.210	20.204	EPSD	COSMIC	8.808	Down-regulation
CMGC_CDK_CDK5_CDK5_ST	P06400	RB1	Q00535	CDK5	S612	M605T	605	Missense	distal	-7	no	20.210	20.268	EPSD	COSMIC	8.808	Up-regulation
CMGC_CDK_CDK5_CDK5_ST	P06400	RB1	Q00535	CDK5	S612	L607V	607	Missense	distal	-5	no	20.210	20.373	EPSD	COSMIC	8.808	Up-regulation
CMGC_CDK_CDK5_CDK5_ST	P06400	RB1	Q00535	CDK5	S612	L607I	607	Missense	distal	-5	no	20.210	20.298	EPSD	COSMIC	8.808	Up-regulation
CMGC_CDK_CDK5_CDK5_ST	P06400	RB1	Q00535	CDK5	S618	R611S	611	Missense	distal	-7	no	9.723	9.724	EPSD	COSMIC	8.808	Up-regulation
CMGC_CDK_CDK5_CDK5_ST	P06400	RB1	Q00535	CDK5	S618	T620M	620	Missense	proximal	2	no	9.723	9.525	EPSD	COSMIC	8.808	Down-regulation
CMGC_CDK_CDK5_CDK5_ST	P06400	RB1	Q00535	CDK5	S618	S612P	612	Missense	distal	-6	no	9.723	9.684	EPSD	COSMIC	8.808	Down-regulation
CMGC_CDK_CDK5_CDK5_ST	P06400	RB1	Q00535	CDK5	S618	R621C	621	Missense	distal	3	no	9.723	7.428	EPSD	COSMIC	8.808	Loss
CMGC_CDK_CDK5_CDK5_ST	P06400	RB1	Q00535	CDK5	S618	R621S	621	Missense	distal	3	no	9.723	8.305	EPSD	COSMIC;GDSC	8.808	Loss
CMGC_CDK_CDK5_CDK5_ST	P06400	RB1	Q00535	CDK5	S618	T625A	625	Missense	distal	7	no	9.723	9.715	EPSD	COSMIC	8.808	Down-regulation
CMGC_CDK_CDK5_CDK5_ST	P06400	RB1	Q00535	CDK5	S618	R621P	621	Missense	distal	3	no	9.723	8.325	EPSD	COSMIC	8.808	Loss
CMGC_CDK_CDK5_CDK5_ST	P06400	RB1	Q00535	CDK5	T620	T620M	620	Missense	central	0	yes	9.249	0.000	EPSD	COSMIC	8.808	Loss
CMGC_CDK_CDK5_CDK5_ST	P06400	RB1	Q00535	CDK5	T620	A626G	626	Missense	distal	6	no	9.249	9.251	EPSD	COSMIC	8.808	Up-regulation
CMGC_CDK_CDK5_CDK5_ST	P06400	RB1	Q00535	CDK5	T620	R621C	621	Missense	proximal	1	no	9.249	-2.478	EPSD	COSMIC	8.808	Loss
CMGC_CDK_CDK5_CDK5_ST	P06400	RB1	Q00535	CDK5	T620	R621S	621	Missense	proximal	1	no	9.249	6.295	EPSD	COSMIC;GDSC	8.808	Loss
CMGC_CDK_CDK5_CDK5_ST	P06400	RB1	Q00535	CDK5	T620	T625A	625	Missense	distal	5	no	9.249	9.115	EPSD	COSMIC	8.808	Down-regulation
CMGC_CDK_CDK5_CDK5_ST	P06400	RB1	Q00535	CDK5	T620	R621P	621	Missense	proximal	1	no	9.249	18.196	EPSD	COSMIC	8.808	Up-regulation
CMGC_CDK_CDK5_CDK5_ST	P06400	RB1	Q00535	CDK5	T633	S634P	634	Missense	proximal	1	no	3.969	15.870	EPSD	COSMIC	8.808	Gain
CMGC_CDK_CDK5_CDK5_ST	P06400	RB1	Q00535	CDK5	S780	P776R	776	Missense	distal	-4	no	18.526	18.411	EPSD	COSMIC	8.808	Down-regulation
CMGC_CDK_CDK5_CDK5_ST	P06400	RB1	Q00535	CDK5	S780	H784Y	784	Missense	distal	4	no	18.526	18.464	EPSD	COSMIC	8.808	Down-regulation
CMGC_CDK_CDK5_CDK5_ST	P06400	RB1	Q00535	CDK5	S780	P777S	777	Missense	distal	-3	no	18.526	18.521	EPSD	COSMIC	8.808	Down-regulation
CMGC_CDK_CDK5_CDK5_ST	P06400	RB1	Q00535	CDK5	S780	P786S	786	Missense	distal	6	no	18.526	18.527	EPSD	COSMIC	8.808	Up-regulation
CMGC_CDK_CDK5_CDK5_ST	P06400	RB1	Q00535	CDK5	S780	S773F	773	Missense	distal	-7	no	18.526	18.442	EPSD	COSMIC	8.808	Down-regulation
CMGC_CDK_CDK5_CDK5_ST	P06400	RB1	Q00535	CDK5	S788	S795L	795	Missense	distal	7	no	19.412	19.400	EPSD	COSMIC	8.808	Down-regulation
CMGC_CDK_CDK5_CDK5_ST	P06400	RB1	Q00535	CDK5	S788	H784Y	784	Missense	distal	-4	no	19.412	19.113	EPSD	COSMIC	8.808	Down-regulation
CMGC_CDK_CDK5_CDK5_ST	P06400	RB1	Q00535	CDK5	S788	S794I	794	Missense	distal	6	no	19.412	19.405	EPSD	COSMIC	8.808	Down-regulation
CMGC_CDK_CDK5_CDK5_ST	P06400	RB1	Q00535	CDK5	S788	P786S	786	Missense	proximal	-2	no	19.412	19.313	EPSD	COSMIC	8.808	Down-regulation
CMGC_CDK_CDK5_CDK5_ST	P06400	RB1	Q00535	CDK5	S788	P793S	793	Missense	distal	5	no	19.412	19.425	EPSD	COSMIC;CCLE	8.808	Up-regulation
CMGC_CDK_CDK5_CDK5_ST	P06400	RB1	Q00535	CDK5	S795	S795L	795	Missense	central	0	yes	19.344	0.000	PhosphoSitePlus;EPSD	COSMIC	8.808	Loss
CMGC_CDK_CDK5_CDK5_ST	P06400	RB1	Q00535	CDK5	S795	G802R	802	Missense	distal	7	no	19.344	19.355	PhosphoSitePlus;EPSD	COSMIC	8.808	Up-regulation
CMGC_CDK_CDK5_CDK5_ST	P06400	RB1	Q00535	CDK5	S795	R798Q	798	Missense	distal	3	no	19.344	17.541	PhosphoSitePlus;EPSD	COSMIC;GDSC;CCLE	8.808	Down-regulation
CMGC_CDK_CDK5_CDK5_ST	P06400	RB1	Q00535	CDK5	S795	S794I	794	Missense	proximal	-1	no	19.344	19.341	PhosphoSitePlus;EPSD	COSMIC	8.808	Down-regulation
CMGC_CDK_CDK5_CDK5_ST	P06400	RB1	Q00535	CDK5	S795	G801A	801	Missense	distal	6	no	19.344	19.342	PhosphoSitePlus;EPSD	COSMIC	8.808	Down-regulation
CMGC_CDK_CDK5_CDK5_ST	P06400	RB1	Q00535	CDK5	S795	P793S	793	Missense	proximal	-2	no	19.344	19.245	PhosphoSitePlus;EPSD	COSMIC;CCLE	8.808	Down-regulation
CMGC_CDK_CDK5_CDK5_ST	P06400	RB1	Q00535	CDK5	S807	G802R	802	Missense	distal	-5	no	19.364	19.616	EPSD;PhosphoSitePlus	COSMIC	8.808	Up-regulation
CMGC_CDK_CDK5_CDK5_ST	P06400	RB1	Q00535	CDK5	S807	K814T	814	Missense	distal	7	no	19.364	19.356	EPSD;PhosphoSitePlus	COSMIC	8.808	Down-regulation
CMGC_CDK_CDK5_CDK5_ST	P06400	RB1	Q00535	CDK5	S807	G801A	801	Missense	distal	-6	no	19.364	19.345	EPSD;PhosphoSitePlus	COSMIC	8.808	Down-regulation
CMGC_CDK_CDK5_CDK5_ST	P06400	RB1	Q00535	CDK5	S811	G818S	818	Missense	distal	7	no	19.583	19.592	EPSD;PhosphoSitePlus	COSMIC	8.808	Up-regulation
CMGC_CDK_CDK5_CDK5_ST	P06400	RB1	Q00535	CDK5	S811	G818C	818	Missense	distal	7	no	19.583	19.578	EPSD;PhosphoSitePlus	COSMIC	8.808	Down-regulation
CMGC_CDK_CDK5_CDK5_ST	P06400	RB1	Q00535	CDK5	S811	K814T	814	Missense	distal	3	no	19.583	18.401	EPSD;PhosphoSitePlus	COSMIC	8.808	Down-regulation
CMGC_CDK_CDK5_CDK5_ST	P06400	RB1	Q00535	CDK5	T821	G818S	818	Missense	distal	-3	no	18.599	18.639	EPSD	COSMIC	8.808	Up-regulation
CMGC_CDK_CDK5_CDK5_ST	P06400	RB1	Q00535	CDK5	T821	P822S	822	Missense	proximal	1	no	18.599	6.698	EPSD	COSMIC	8.808	Loss
CMGC_CDK_CDK5_CDK5_ST	P06400	RB1	Q00535	CDK5	T821	G818C	818	Missense	distal	-3	no	18.599	18.576	EPSD	COSMIC	8.808	Down-regulation
CMGC_CDK_CDK5_CDK5_ST	P06400	RB1	Q00535	CDK5	T821	K814T	814	Missense	distal	-7	no	18.599	18.567	EPSD	COSMIC	8.808	Down-regulation
CMGC_CDK_CDK5_CDK5_ST	P06400	RB1	Q00535	CDK5	T826	S829L	829	Missense	distal	3	no	17.199	16.147	EPSD	COSMIC	8.808	Down-regulation
CMGC_CDK_CDK5_CDK5_ST	P06400	RB1	Q00535	CDK5	T826	P822S	822	Missense	distal	-4	no	17.199	17.545	EPSD	COSMIC	8.808	Up-regulation
CMGC_CDK_CDK5_CDK5_ST	P06400	RB1	Q00535	CDK5	S866	L859F	859	Missense	distal	-7	no	9.352	9.324	EPSD	COSMIC	8.808	Down-regulation
CMGC_CDK_CDK5_CDK5_ST	P06400	RB1	Q00535	CDK5	S866	K873T	873	Missense	distal	7	no	9.352	9.343	EPSD	COSMIC	8.808	Down-regulation
CMGC_CDK_CDK5_CDK5_ST	P06400	RB1	Q00535	CDK5	S923	D918N	918	Missense	distal	-5	no	9.270	9.344	EPSD	COSMIC	8.808	Up-regulation
CMGC_CDK_CDK5_CDK5_ST	Q16236	NFE2L2	Q00535	CDK5	S40	F39S	39	Missense	proximal	-1	no	10.192	10.201	EPSD	COSMIC	8.808	Up-regulation
CMGC_CDK_CDK5_CDK5_ST	Q16236	NFE2L2	Q00535	CDK5	S40	D38H	38	Missense	proximal	-2	no	10.192	10.210	EPSD	COSMIC	8.808	Up-regulation
CMGC_CDK_CDK5_CDK5_ST	Q16236	NFE2L2	Q00535	CDK5	S40	F37S	37	Missense	distal	-3	no	10.192	10.270	EPSD	COSMIC	8.808	Up-regulation
CMGC_CDK_CDK5_CDK5_ST	Q16236	NFE2L2	Q00535	CDK5	S40	R43Q	43	Missense	distal	3	no	10.192	8.389	EPSD	COSMIC;GDSC	8.808	Loss
CMGC_CDK_CDK5_CDK5_ST	Q16236	NFE2L2	Q00535	CDK5	S40	S40N	40	Missense	central	0	yes	10.192	0.000	EPSD	COSMIC	8.808	Loss
CMGC_CDK_CDK5_CDK5_ST	Q16236	NFE2L2	Q00535	CDK5	S40	F37L	37	Missense	distal	-3	no	10.192	10.214	EPSD	COSMIC	8.808	Up-regulation
CMGC_CDK_CDK5_CDK5_ST	Q16236	NFE2L2	Q00535	CDK5	S40	E45K	45	Missense	distal	5	no	10.192	10.443	EPSD	COSMIC	8.808	Up-regulation
CMGC_CDK_CDK5_CDK5_ST	Q16236	NFE2L2	Q00535	CDK5	S40	R42Q	42	Missense	proximal	2	no	10.192	10.053	EPSD	COSMIC	8.808	Down-regulation
CMGC_CDK_CDK5_CDK5_ST	Q16236	NFE2L2	Q00535	CDK5	S40	F39L	39	Missense	proximal	-1	no	10.192	10.195	EPSD	COSMIC	8.808	Up-regulation
CMGC_CDK_CDK5_CDK5_ST	Q16236	NFE2L2	Q00535	CDK5	S40	F39V	39	Missense	proximal	-1	no	10.192	10.199	EPSD	COSMIC	8.808	Up-regulation
CMGC_CDK_CDK5_CDK5_ST	Q16236	NFE2L2	Q00535	CDK5	S215	M212T	212	Missense	distal	-3	no	17.627	17.690	EPSD	COSMIC	8.808	Up-regulation
CMGC_CDK_CDK5_CDK5_ST	Q16236	NFE2L2	Q00535	CDK5	S215	T211I	211	Missense	distal	-4	no	17.627	17.514	EPSD	COSMIC	8.808	Down-regulation
CMGC_CDK_CDK5_CDK5_ST	Q16236	NFE2L2	Q00535	CDK5	S215	M212L	212	Missense	distal	-3	no	17.627	17.637	EPSD	COSMIC	8.808	Up-regulation
CMGC_CDK_CDK5_CDK5_ST	Q16236	NFE2L2	Q00535	CDK5	S215	E222Q	222	Missense	distal	7	no	17.627	17.632	EPSD	COSMIC	8.808	Up-regulation
CMGC_CDK_CDK5_CDK5_ST	Q16236	NFE2L2	Q00535	CDK5	S243	L247I	247	Missense	distal	4	no	17.163	17.202	EPSD	COSMIC	8.808	Up-regulation
CMGC_CDK_CDK5_CDK5_ST	Q16236	NFE2L2	Q00535	CDK5	S243	P244A	244	Missense	proximal	1	no	17.163	6.137	EPSD	COSMIC	8.808	Loss
CMGC_CDK_CDK5_CDK5_ST	Q16236	NFE2L2	Q00535	CDK5	S243	P244L	244	Missense	proximal	1	no	17.163	5.213	EPSD	COSMIC	8.808	Loss
CMGC_CDK_CDK5_CDK5_ST	Q16236	NFE2L2	Q00535	CDK5	S243	E238Q	238	Missense	distal	-5	no	17.163	17.257	EPSD	COSMIC	8.808	Up-regulation
CMGC_CDK_CDK5_CDK5_ST	Q16236	NFE2L2	Q00535	CDK5	S243	L247F	247	Missense	distal	4	no	17.163	17.134	EPSD	COSMIC	8.808	Down-regulation
CMGC_CDK_CDK5_CDK5_ST	Q16236	NFE2L2	Q00535	CDK5	S243	S243F	243	Missense	central	0	yes	17.163	0.000	EPSD	COSMIC	8.808	Loss
CMGC_CDK_CDK5_CDK5_ST	Q16236	NFE2L2	Q00535	CDK5	S301	A303V	303	Missense	proximal	2	no	18.352	18.433	EPSD	COSMIC	8.808	Up-regulation
CMGC_CDK_CDK5_CDK5_ST	Q16236	NFE2L2	Q00535	CDK5	S301	S298N	298	Missense	distal	-3	no	18.352	18.334	EPSD	COSMIC	8.808	Down-regulation
CMGC_CDK_CDK5_CDK5_ST	Q16236	NFE2L2	Q00535	CDK5	S301	P300H	300	Missense	proximal	-1	no	18.352	18.350	EPSD	COSMIC	8.808	Down-regulation
CMGC_CDK_CDK5_CDK5_ST	Q16236	NFE2L2	Q00535	CDK5	S351	S353T	353	Missense	proximal	2	no	18.757	18.781	EPSD	COSMIC	8.808	Up-regulation
CMGC_CDK_CDK5_CDK5_ST	Q16236	NFE2L2	Q00535	CDK5	S351	S353N	353	Missense	proximal	2	no	18.757	18.710	EPSD	COSMIC	8.808	Down-regulation
CMGC_CDK_CDK5_CDK5_ST	Q16236	NFE2L2	Q00535	CDK5	S351	A355T	355	Missense	distal	4	no	18.757	18.816	EPSD	COSMIC	8.808	Up-regulation
CMGC_CDK_CDK5_CDK5_ST	Q16236	NFE2L2	Q00535	CDK5	S351	S353F	353	Missense	proximal	2	no	18.757	18.547	EPSD	COSMIC	8.808	Down-regulation
CMGC_CDK_CDK5_CDK5_ST	Q16236	NFE2L2	Q00535	CDK5	S351	S351R	351	Missense	central	0	yes	18.757	0.000	EPSD	COSMIC	8.808	Loss
CMGC_CDK_CDK5_CDK5_ST	Q16236	NFE2L2	Q00535	CDK5	S356	S353T	353	Missense	distal	-3	no	18.829	18.827	EPSD	COSMIC	8.808	Down-regulation
CMGC_CDK_CDK5_CDK5_ST	Q16236	NFE2L2	Q00535	CDK5	S356	S353N	353	Missense	distal	-3	no	18.829	18.811	EPSD	COSMIC	8.808	Down-regulation
CMGC_CDK_CDK5_CDK5_ST	Q16236	NFE2L2	Q00535	CDK5	S356	A355T	355	Missense	proximal	-1	no	18.829	18.833	EPSD	COSMIC	8.808	Up-regulation
CMGC_CDK_CDK5_CDK5_ST	Q16236	NFE2L2	Q00535	CDK5	S356	S360F	360	Missense	distal	4	no	18.829	18.717	EPSD	COSMIC	8.808	Down-regulation
CMGC_CDK_CDK5_CDK5_ST	Q16236	NFE2L2	Q00535	CDK5	S356	S353F	353	Missense	distal	-3	no	18.829	18.751	EPSD	COSMIC	8.808	Down-regulation
CMGC_CDK_CDK5_CDK5_ST	Q16236	NFE2L2	Q00535	CDK5	S356	S351R	351	Missense	distal	-5	no	18.829	18.909	EPSD	COSMIC	8.808	Up-regulation
CMGC_CDK_CDK5_CDK5_ST	Q16236	NFE2L2	Q00535	CDK5	T395	G401V	401	Missense	distal	6	no	18.245	18.252	PhosphoSitePlus;EPSD	COSMIC	8.808	Up-regulation
CMGC_CDK_CDK5_CDK5_ST	Q16236	NFE2L2	Q00535	CDK5	T395	S399Y	399	Missense	distal	4	no	18.245	18.160	PhosphoSitePlus;EPSD	COSMIC	8.808	Down-regulation
CMGC_CDK_CDK5_CDK5_ST	Q16236	NFE2L2	Q00535	CDK5	T395	G392D	392	Missense	distal	-3	no	18.245	18.246	PhosphoSitePlus;EPSD	COSMIC	8.808	Up-regulation
CMGC_CDK_CDK5_CDK5_ST	Q16236	NFE2L2	Q00535	CDK5	T395	S399F	399	Missense	distal	4	no	18.245	18.133	PhosphoSitePlus;EPSD	COSMIC	8.808	Down-regulation
CMGC_CDK_CDK5_CDK5_ST	Q16236	NFE2L2	Q00535	CDK5	T395	V388A	388	Missense	distal	-7	no	18.245	18.209	PhosphoSitePlus;EPSD	COSMIC	8.808	Down-regulation
CMGC_CDK_CDK5_CDK5_ST	Q16236	NFE2L2	Q00535	CDK5	S408	G401E	401	Missense	distal	-7	no	17.464	17.470	EPSD	COSMIC	8.808	Up-regulation
CMGC_CDK_CDK5_CDK5_ST	Q16236	NFE2L2	Q00535	CDK5	S408	G401V	401	Missense	distal	-7	no	17.464	17.498	EPSD	COSMIC	8.808	Up-regulation
CMGC_CDK_CDK5_CDK5_ST	Q16236	NFE2L2	Q00535	CDK5	S408	V404A	404	Missense	distal	-4	no	17.464	17.044	EPSD	COSMIC	8.808	Down-regulation
CMGC_CDK_CDK5_CDK5_ST	Q16236	NFE2L2	Q00535	CDK5	S408	S408L	408	Missense	central	0	yes	17.464	0.000	EPSD	COSMIC	8.808	Loss
CMGC_CDK_CDK5_CDK5_ST	Q16236	NFE2L2	Q00535	CDK5	S408	L407F	407	Missense	proximal	-1	no	17.464	17.461	EPSD	COSMIC	8.808	Down-regulation
CMGC_CDK_CDK5_CDK5_ST	Q16236	NFE2L2	Q00535	CDK5	S408	M403L	403	Missense	distal	-5	no	17.464	17.526	EPSD	COSMIC	8.808	Up-regulation
CMGC_CDK_CDK5_CDK5_ST	Q16236	NFE2L2	Q00535	CDK5	S408	G412V	412	Missense	distal	4	no	17.464	17.495	EPSD	COSMIC	8.808	Up-regulation
CMGC_CDK_CDK5_CDK5_ST	Q16236	NFE2L2	Q00535	CDK5	T425	D419N	419	Missense	distal	-6	no	17.782	17.821	EPSD	COSMIC	8.808	Up-regulation
CMGC_CDK_CDK5_CDK5_ST	Q16236	NFE2L2	Q00535	CDK5	T425	E427D	427	Missense	proximal	2	no	17.782	17.778	EPSD	COSMIC	8.808	Down-regulation
CMGC_CDK_CDK5_CDK5_ST	Q16236	NFE2L2	Q00535	CDK5	T425	E427K	427	Missense	proximal	2	no	17.782	18.032	EPSD	COSMIC	8.808	Up-regulation
CMGC_CDK_CDK5_CDK5_ST	Q16236	NFE2L2	Q00535	CDK5	S433	T439P	439	Missense	distal	6	no	18.388	18.387	EPSD;PhosphoSitePlus	COSMIC	8.808	Down-regulation
CMGC_CDK_CDK5_CDK5_ST	Q16236	NFE2L2	Q00535	CDK5	S433	G435V	435	Missense	proximal	2	no	18.388	18.448	EPSD;PhosphoSitePlus	COSMIC	8.808	Up-regulation
CMGC_CDK_CDK5_CDK5_ST	Q16236	NFE2L2	Q00535	CDK5	S433	E427D	427	Missense	distal	-6	no	18.388	18.378	EPSD;PhosphoSitePlus	COSMIC	8.808	Down-regulation
CMGC_CDK_CDK5_CDK5_ST	Q16236	NFE2L2	Q00535	CDK5	S433	E427K	427	Missense	distal	-6	no	18.388	18.518	EPSD;PhosphoSitePlus	COSMIC	8.808	Up-regulation
CMGC_CDK_CDK5_CDK5_ST	Q16236	NFE2L2	Q00535	CDK5	S433	R437S	437	Missense	distal	4	no	18.388	18.371	EPSD;PhosphoSitePlus	COSMIC	8.808	Down-regulation
CMGC_CDK_CDK5_CDK5_ST	Q16236	NFE2L2	Q00535	CDK5	T439	T439P	439	Missense	central	0	yes	17.634	0.000	EPSD;PhosphoSitePlus	COSMIC	8.808	Loss
CMGC_CDK_CDK5_CDK5_ST	Q16236	NFE2L2	Q00535	CDK5	T439	G435V	435	Missense	distal	-4	no	17.634	17.993	EPSD;PhosphoSitePlus	COSMIC	8.808	Up-regulation
CMGC_CDK_CDK5_CDK5_ST	Q16236	NFE2L2	Q00535	CDK5	T439	D444H	444	Missense	distal	5	no	17.634	17.727	EPSD;PhosphoSitePlus	COSMIC	8.808	Up-regulation
CMGC_CDK_CDK5_CDK5_ST	Q16236	NFE2L2	Q00535	CDK5	T439	R437S	437	Missense	proximal	-2	no	17.634	17.590	EPSD;PhosphoSitePlus	COSMIC	8.808	Down-regulation
CMGC_CDK_CDK5_CDK5_ST	Q16236	NFE2L2	Q00535	CDK5	S577	E571K	571	Missense	distal	-6	no	16.908	17.037	EPSD	COSMIC	8.808	Up-regulation
CMGC_CDK_CDK5_CDK5_ST	Q16236	NFE2L2	Q00535	CDK5	S577	E580K	580	Missense	distal	3	no	16.908	19.194	EPSD	COSMIC	8.808	Up-regulation
CMGC_CDK_CDK5_CDK5_ST	Q16236	NFE2L2	Q00535	CDK5	S577	S577F	577	Missense	central	0	yes	16.908	0.000	EPSD	COSMIC	8.808	Loss
CMGC_CDK_CDK5_CDK5_ST	Q16236	NFE2L2	Q00535	CDK5	S577	Y581N	581	Missense	distal	4	no	16.908	16.962	EPSD	COSMIC	8.808	Up-regulation
CMGC_CDK_CDK5_CDK5_ST	P35968	KDR	Q00535	CDK5	S229	P230L	230	Missense	proximal	1	no	18.514	6.565	PhosphoSitePlus	COSMIC;GDSC;CCLE	8.808	Loss
CMGC_CDK_CDK5_CDK5_ST	P35968	KDR	Q00535	CDK5	S229	D225Y	225	Missense	distal	-4	no	18.514	18.210	PhosphoSitePlus	COSMIC	8.808	Down-regulation
CMGC_CDK_CDK5_CDK5_ST	P35968	KDR	Q00535	CDK5	S229	D225N	225	Missense	distal	-4	no	18.514	18.678	PhosphoSitePlus	COSMIC	8.808	Up-regulation
CMGC_CDK_CDK5_CDK5_ST	P35968	KDR	Q00535	CDK5	S229	I234M	234	Missense	distal	5	no	18.514	18.400	PhosphoSitePlus	COSMIC;CCLE	8.808	Down-regulation
CMGC_CDK_CDK5_CDK5_ST	P35968	KDR	Q00535	CDK5	S229	S231Y	231	Missense	proximal	2	no	18.514	18.363	PhosphoSitePlus	COSMIC	8.808	Down-regulation
CMGC_CDK_CDK5_CDK5_ST	P35968	KDR	Q00535	CDK5	S229	Y224D	224	Missense	distal	-5	no	18.514	18.598	PhosphoSitePlus	COSMIC	8.808	Up-regulation
CMGC_CDK_CDK5_CDK5_ST	P35968	KDR	Q00535	CDK5	S229	V226M	226	Missense	distal	-3	no	18.514	18.458	PhosphoSitePlus	COSMIC	8.808	Down-regulation
CMGC_CDK_CDK5_CDK5_ST	P35968	KDR	Q00535	CDK5	S877	E878Q	878	Missense	proximal	1	no	-3.033	10.202	EPSD	COSMIC	8.808	Gain
CMGC_CDK_CDK5_CDK5_ST	P35968	KDR	Q00535	CDK5	S1231	S1231R	1231	Missense	central	0	yes	10.206	0.000	EPSD	COSMIC	8.808	Loss
CMGC_CDK_CDK5_CDK5_ST	P35968	KDR	Q00535	CDK5	S1231	P1233F	1233	Missense	proximal	2	no	10.206	9.979	EPSD	COSMIC	8.808	Down-regulation
CMGC_CDK_CDK5_CDK5_ST	P35968	KDR	Q00535	CDK5	S1231	V1234L	1234	Missense	distal	3	no	10.206	9.127	EPSD	COSMIC	8.808	Down-regulation
CMGC_CDK_CDK5_CDK5_ST	P35968	KDR	Q00535	CDK5	S1231	V1236E	1236	Missense	distal	5	no	10.206	10.131	EPSD	COSMIC	8.808	Down-regulation
CMGC_CDK_CDK5_CDK5_ST	P35968	KDR	Q00535	CDK5	S1231	N1226K	1226	Missense	distal	-5	no	10.206	10.413	EPSD	COSMIC	8.808	Up-regulation
CMGC_CDK_CDK5_CDK5_ST	P35968	KDR	Q00535	CDK5	S1279	R1275K	1275	Missense	distal	-4	no	16.619	16.955	EPSD	COSMIC	8.808	Up-regulation
CMGC_CDK_CDK5_CDK5_ST	P35968	KDR	Q00535	CDK5	S1279	D1274Y	1274	Missense	distal	-5	no	16.619	16.535	EPSD	COSMIC	8.808	Down-regulation
CMGC_CDK_CDK5_CDK5_ST	P35968	KDR	Q00535	CDK5	S1279	S1281F	1281	Missense	proximal	2	no	16.619	16.409	EPSD	COSMIC;GDSC;CCLE	8.808	Down-regulation
CMGC_CDK_CDK5_CDK5_ST	P35968	KDR	Q00535	CDK5	S1279	G1283R	1283	Missense	distal	4	no	16.619	16.686	EPSD	COSMIC	8.808	Up-regulation
CMGC_CDK_CDK5_CDK5_ST	P35968	KDR	Q00535	CDK5	S1279	G1284R	1284	Missense	distal	5	no	16.619	16.785	EPSD	COSMIC	8.808	Up-regulation
CMGC_CDK_CDK5_CDK5_ST	P35968	KDR	Q00535	CDK5	S1279	S1279Y	1279	Missense	central	0	yes	16.619	0.000	EPSD	COSMIC	8.808	Loss
CMGC_CDK_CDK5_CDK5_ST	P35968	KDR	Q00535	CDK5	S1279	T1276A	1276	Missense	distal	-3	no	16.619	16.573	EPSD	COSMIC	8.808	Down-regulation
CMGC_CDK_CDK5_CDK5_ST	P35968	KDR	Q00535	CDK5	S1290	S1290N	1290	Missense	central	0	yes	9.427	0.000	EPSD	COSMIC;GDSC;CCLE	8.808	Loss
CMGC_CDK_CDK5_CDK5_ST	P35968	KDR	Q00535	CDK5	S1290	G1283R	1283	Missense	distal	-7	no	9.427	9.479	EPSD	COSMIC	8.808	Up-regulation
CMGC_CDK_CDK5_CDK5_ST	P35968	KDR	Q00535	CDK5	S1290	V1294M	1294	Missense	distal	4	no	9.427	9.351	EPSD	COSMIC	8.808	Down-regulation
CMGC_CDK_CDK5_CDK5_ST	P35968	KDR	Q00535	CDK5	S1290	G1284R	1284	Missense	distal	-6	no	9.427	9.528	EPSD	COSMIC	8.808	Up-regulation
CMGC_CDK_CDK5_CDK5_ST	P35968	KDR	Q00535	CDK5	S1290	R1291K	1291	Missense	proximal	1	no	9.427	0.196	EPSD	COSMIC	8.808	Loss
CMGC_CDK_CDK5_CDK5_ST	P35968	KDR	Q00535	CDK5	S1290	A1295T	1295	Missense	distal	5	no	9.427	9.561	EPSD	COSMIC	8.808	Up-regulation
CMGC_CDK_CDK5_CDK5_ST	P35222	CTNNB1	Q00535	CDK5	S23	H24Q	24	Missense	proximal	1	no	-0.080	9.456	EPSD	COSMIC	8.808	Gain
CMGC_CDK_CDK5_CDK5_ST	P35222	CTNNB1	Q00535	CDK5	S23	H24R	24	Missense	proximal	1	no	-0.080	9.485	EPSD	COSMIC	8.808	Gain
CMGC_CDK_CDK5_CDK5_ST	P35222	CTNNB1	Q00535	CDK5	S37	G38P	38	Missense	proximal	1	no	-2.348	19.068	EPSD	COSMIC	8.808	Gain
CMGC_CDK_CDK5_CDK5_ST	P35222	CTNNB1	Q00535	CDK5	T40	T41P	41	Missense	proximal	1	no	6.744	17.231	EPSD	COSMIC	8.808	Gain
CMGC_CDK_CDK5_CDK5_ST	P35222	CTNNB1	Q00535	CDK5	T42	A43P	43	Missense	proximal	1	no	6.527	17.554	EPSD	COSMIC	8.808	Gain
CMGC_CDK_CDK5_CDK5_ST	P35222	CTNNB1	Q00535	CDK5	S45	L46P	46	Missense	proximal	1	no	6.193	18.143	EPSD	COSMIC	8.808	Gain
CMGC_CDK_CDK5_CDK5_ST	P35222	CTNNB1	Q00535	CDK5	S45	L46Q	46	Missense	proximal	1	no	6.193	9.167	EPSD	COSMIC	8.808	Gain
CMGC_CDK_CDK5_CDK5_ST	P35222	CTNNB1	Q00535	CDK5	S184	A187T	187	Missense	distal	3	no	8.504	9.284	EPSD	COSMIC	8.808	Gain
CMGC_CDK_CDK5_CDK5_ST	P35222	CTNNB1	Q00535	CDK5	S191	P192S	192	Missense	proximal	1	no	16.522	4.621	EPSD;PhosphoSitePlus	COSMIC	8.808	Loss
CMGC_CDK_CDK5_CDK5_ST	P35222	CTNNB1	Q00535	CDK5	S191	A187T	187	Missense	distal	-4	no	16.522	16.922	EPSD;PhosphoSitePlus	COSMIC	8.808	Up-regulation
CMGC_CDK_CDK5_CDK5_ST	P35222	CTNNB1	Q00535	CDK5	S191	R190C	190	Missense	proximal	-1	no	16.522	16.516	EPSD;PhosphoSitePlus	COSMIC	8.808	Down-regulation
CMGC_CDK_CDK5_CDK5_ST	P35222	CTNNB1	Q00535	CDK5	S191	A187D	187	Missense	distal	-4	no	16.522	16.747	EPSD;PhosphoSitePlus	COSMIC	8.808	Up-regulation
CMGC_CDK_CDK5_CDK5_ST	P35222	CTNNB1	Q00535	CDK5	S191	P192H	192	Missense	proximal	1	no	16.522	-1.990	EPSD;PhosphoSitePlus	COSMIC	8.808	Loss
CMGC_CDK_CDK5_CDK5_ST	P35222	CTNNB1	Q00535	CDK5	S191	I188M	188	Missense	distal	-3	no	16.522	16.481	EPSD;PhosphoSitePlus	COSMIC	8.808	Down-regulation
CMGC_CDK_CDK5_CDK5_ST	P35222	CTNNB1	Q00535	CDK5	S191	R190H	190	Missense	proximal	-1	no	16.522	16.520	EPSD;PhosphoSitePlus	COSMIC	8.808	Down-regulation
CMGC_CDK_CDK5_CDK5_ST	P35222	CTNNB1	Q00535	CDK5	S191	I198L	198	Missense	distal	7	no	16.522	16.516	EPSD;PhosphoSitePlus	COSMIC	8.808	Down-regulation
CMGC_CDK_CDK5_CDK5_ST	P35222	CTNNB1	Q00535	CDK5	S191	A187V	187	Missense	distal	-4	no	16.522	16.942	EPSD;PhosphoSitePlus	COSMIC	8.808	Up-regulation
CMGC_CDK_CDK5_CDK5_ST	P35222	CTNNB1	Q00535	CDK5	S191	R185K	185	Missense	distal	-6	no	16.522	16.558	EPSD;PhosphoSitePlus	COSMIC	8.808	Up-regulation
CMGC_CDK_CDK5_CDK5_ST	P35222	CTNNB1	Q00535	CDK5	S246	M243T	243	Missense	distal	-3	no	17.989	18.052	PhosphoSitePlus;EPSD	COSMIC	8.808	Up-regulation
CMGC_CDK_CDK5_CDK5_ST	P35222	CTNNB1	Q00535	CDK5	S246	S246L	246	Missense	central	0	yes	17.989	0.000	PhosphoSitePlus;EPSD	COSMIC	8.808	Loss
CMGC_CDK_CDK5_CDK5_ST	P35222	CTNNB1	Q00535	CDK5	S246	G245A	245	Missense	proximal	-1	no	17.989	17.988	PhosphoSitePlus;EPSD	COSMIC;GDSC	8.808	Down-regulation
CMGC_CDK_CDK5_CDK5_ST	P35222	CTNNB1	Q00535	CDK5	S246	A239V	239	Missense	distal	-7	no	17.989	18.025	PhosphoSitePlus;EPSD	COSMIC	8.808	Up-regulation
CMGC_CDK_CDK5_CDK5_ST	P35222	CTNNB1	Q00535	CDK5	S246	K242E	242	Missense	distal	-4	no	17.989	17.486	PhosphoSitePlus;EPSD	COSMIC	8.808	Down-regulation
CMGC_CDK_CDK5_CDK5_ST	P35222	CTNNB1	Q00535	CDK5	S246	A239G	239	Missense	distal	-7	no	17.989	17.991	PhosphoSitePlus;EPSD	COSMIC	8.808	Up-regulation
CMGC_CDK_CDK5_CDK5_ST	P35222	CTNNB1	Q00535	CDK5	T289	N287S	287	Missense	proximal	-2	no	9.190	9.303	EPSD	COSMIC;GDSC	8.808	Up-regulation
CMGC_CDK_CDK5_CDK5_ST	P35222	CTNNB1	Q00535	CDK5	T289	V283A	283	Missense	distal	-6	no	9.190	9.120	EPSD	COSMIC	8.808	Down-regulation
CMGC_CDK_CDK5_CDK5_ST	P35222	CTNNB1	Q00535	CDK5	T289	A295D	295	Missense	distal	6	no	9.190	9.191	EPSD	COSMIC	8.808	Up-regulation
CMGC_CDK_CDK5_CDK5_ST	P35222	CTNNB1	Q00535	CDK5	T289	A295T	295	Missense	distal	6	no	9.190	9.202	EPSD	COSMIC	8.808	Up-regulation
CMGC_CDK_CDK5_CDK5_ST	P35222	CTNNB1	Q00535	CDK5	T547	T551K	551	Missense	distal	4	no	10.356	10.422	EPSD	COSMIC	8.808	Up-regulation
CMGC_CDK_CDK5_CDK5_ST	P35222	CTNNB1	Q00535	CDK5	T547	R549C	549	Missense	proximal	2	no	10.356	10.089	EPSD	COSMIC	8.808	Down-regulation
CMGC_CDK_CDK5_CDK5_ST	P35222	CTNNB1	Q00535	CDK5	T547	Q545K	545	Missense	proximal	-2	no	10.356	10.519	EPSD	COSMIC	8.808	Up-regulation
CMGC_CDK_CDK5_CDK5_ST	P35222	CTNNB1	Q00535	CDK5	T547	A543T	543	Missense	distal	-4	no	10.356	10.755	EPSD	COSMIC	8.808	Up-regulation
CMGC_CDK_CDK5_CDK5_ST	P35222	CTNNB1	Q00535	CDK5	T547	R550H	550	Missense	distal	3	no	10.356	9.336	EPSD	COSMIC	8.808	Down-regulation
CMGC_CDK_CDK5_CDK5_ST	P35222	CTNNB1	Q00535	CDK5	T547	L540F	540	Missense	distal	-7	no	10.356	10.328	EPSD	COSMIC	8.808	Down-regulation
CMGC_CDK_CDK5_CDK5_ST	P35222	CTNNB1	Q00535	CDK5	T547	R550L	550	Missense	distal	3	no	10.356	7.886	EPSD	COSMIC	8.808	Loss
CMGC_CDK_CDK5_CDK5_ST	P35222	CTNNB1	Q00535	CDK5	T547	A543V	543	Missense	distal	-4	no	10.356	10.775	EPSD	COSMIC	8.808	Up-regulation
CMGC_CDK_CDK5_CDK5_ST	P35222	CTNNB1	Q00535	CDK5	T547	S552F	552	Missense	distal	5	no	10.356	10.117	EPSD	COSMIC	8.808	Down-regulation
CMGC_CDK_CDK5_CDK5_ST	P35222	CTNNB1	Q00535	CDK5	T547	R550Q	550	Missense	distal	3	no	10.356	8.553	EPSD	COSMIC	8.808	Loss
CMGC_CDK_CDK5_CDK5_ST	P35222	CTNNB1	Q00535	CDK5	T547	T551I	551	Missense	distal	4	no	10.356	10.314	EPSD	COSMIC	8.808	Down-regulation
CMGC_CDK_CDK5_CDK5_ST	P35222	CTNNB1	Q00535	CDK5	S605	V600G	600	Missense	distal	-5	no	17.288	17.174	EPSD	COSMIC	8.808	Down-regulation
CMGC_CDK_CDK5_CDK5_ST	P35222	CTNNB1	Q00535	CDK5	S605	R612T	612	Missense	distal	7	no	17.288	17.285	EPSD	COSMIC	8.808	Down-regulation
CMGC_CDK_CDK5_CDK5_ST	P35222	CTNNB1	Q00535	CDK5	S605	V600L	600	Missense	distal	-5	no	17.288	17.125	EPSD	COSMIC;GDSC;CCLE	8.808	Down-regulation
CMGC_CDK_CDK5_CDK5_ST	P35222	CTNNB1	Q00535	CDK5	S605	V600A	600	Missense	distal	-5	no	17.288	17.163	EPSD	COSMIC	8.808	Down-regulation
CMGC_CDK_CDK5_CDK5_ST	P35222	CTNNB1	Q00535	CDK5	S605	F599L	599	Missense	distal	-6	no	17.288	17.339	EPSD	COSMIC	8.808	Up-regulation
CMGC_CDK_CDK5_CDK5_ST	P35222	CTNNB1	Q00535	CDK5	S605	Q611R	611	Missense	distal	6	no	17.288	17.299	EPSD	COSMIC	8.808	Up-regulation
CMGC_CDK_CDK5_CDK5_ST	P35222	CTNNB1	Q00535	CDK5	S605	L603R	603	Missense	proximal	-2	no	17.288	17.649	EPSD	COSMIC	8.808	Up-regulation
CMGC_CDK_CDK5_CDK5_ST	P35222	CTNNB1	Q00535	CDK5	S605	L603Q	603	Missense	proximal	-2	no	17.288	17.512	EPSD	COSMIC	8.808	Up-regulation
CMGC_CDK_CDK5_CDK5_ST	P40763	STAT3	Q00535	CDK5	T196	M200I	200	Missense	distal	4	no	10.155	10.207	EPSD	COSMIC	8.808	Up-regulation
CMGC_CDK_CDK5_CDK5_ST	P40763	STAT3	Q00535	CDK5	T196	K199T	199	Missense	distal	3	no	10.155	8.974	EPSD	COSMIC	8.808	Down-regulation
CMGC_CDK_CDK5_CDK5_ST	P40763	STAT3	Q00535	CDK5	T196	N191D	191	Missense	distal	-5	no	10.155	10.081	EPSD	COSMIC	8.808	Down-regulation
CMGC_CDK_CDK5_CDK5_ST	P40763	STAT3	Q00535	CDK5	T412	L413P	413	Missense	proximal	1	no	4.392	16.342	EPSD	COSMIC	8.808	Gain
CMGC_CDK_CDK5_CDK5_ST	P40763	STAT3	Q00535	CDK5	T714	I711L	711	Missense	distal	-3	no	17.499	17.468	EPSD	COSMIC	8.808	Down-regulation
CMGC_CDK_CDK5_CDK5_ST	P40763	STAT3	Q00535	CDK5	S727	D723N	723	Missense	distal	-4	no	19.471	19.635	PhosphoSitePlus	COSMIC	8.808	Up-regulation
CMGC_CDK_CDK5_CDK5_ST	Q05193	DNM1	Q00535	CDK5	S116	R123G	123	Missense	distal	7	no	17.961	17.950	EPSD	COSMIC	8.808	Down-regulation
CMGC_CDK_CDK5_CDK5_ST	Q05193	DNM1	Q00535	CDK5	S116	P119H	119	Missense	distal	3	no	17.961	18.340	EPSD	COSMIC;GDSC;CCLE	8.808	Up-regulation
CMGC_CDK_CDK5_CDK5_ST	Q05193	DNM1	Q00535	CDK5	S126	L132M	132	Missense	distal	6	no	18.047	18.045	EPSD	COSMIC;GDSC;CCLE	8.808	Down-regulation
CMGC_CDK_CDK5_CDK5_ST	Q05193	DNM1	Q00535	CDK5	S126	R123G	123	Missense	distal	-3	no	18.047	17.992	EPSD	COSMIC	8.808	Down-regulation
CMGC_CDK_CDK5_CDK5_ST	Q05193	DNM1	Q00535	CDK5	S126	P119H	119	Missense	distal	-7	no	18.047	18.021	EPSD	COSMIC;GDSC;CCLE	8.808	Down-regulation
CMGC_CDK_CDK5_CDK5_ST	Q05193	DNM1	Q00535	CDK5	T274	R271C	271	Missense	distal	-3	no	15.902	15.824	EPSD	COSMIC	8.808	Down-regulation
CMGC_CDK_CDK5_CDK5_ST	Q05193	DNM1	Q00535	CDK5	T404	A408T	408	Missense	distal	4	no	16.122	16.182	EPSD	COSMIC	8.808	Up-regulation
CMGC_CDK_CDK5_CDK5_ST	Q05193	DNM1	Q00535	CDK5	T404	G401A	401	Missense	distal	-3	no	16.122	16.116	EPSD	COSMIC	8.808	Down-regulation
CMGC_CDK_CDK5_CDK5_ST	Q05193	DNM1	Q00535	CDK5	T404	F403L	403	Missense	proximal	-1	no	16.122	16.125	EPSD	COSMIC	8.808	Up-regulation
CMGC_CDK_CDK5_CDK5_ST	Q05193	DNM1	Q00535	CDK5	S851	R846G	846	Missense	distal	-5	no	20.799	20.547	EPSD	COSMIC	8.808	Down-regulation
CMGC_CDK_CDK5_CDK5_ST	Q05193	DNM1	Q00535	CDK5	S851	P855Q	855	Missense	distal	4	no	20.799	20.771	EPSD	COSMIC	8.808	Down-regulation
CMGC_CDK_CDK5_CDK5_ST	Q05193	DNM1	Q00535	CDK5	S853	R859S	859	Missense	distal	6	no	8.972	8.965	EPSD	COSMIC	8.808	Down-regulation
CMGC_CDK_CDK5_CDK5_ST	Q05193	DNM1	Q00535	CDK5	S853	R846G	846	Missense	distal	-7	no	8.972	8.920	EPSD	COSMIC	8.808	Down-regulation
CMGC_CDK_CDK5_CDK5_ST	Q05193	DNM1	Q00535	CDK5	S853	P855Q	855	Missense	proximal	2	no	8.972	8.915	EPSD	COSMIC	8.808	Down-regulation
CMGC_CDK_CDK5_CDK5_ST	Q05193	DNM1	Q00535	CDK5	S857	R859S	859	Missense	proximal	2	no	19.199	19.099	EPSD	COSMIC	8.808	Down-regulation
CMGC_CDK_CDK5_CDK5_ST	Q05193	DNM1	Q00535	CDK5	S857	P855Q	855	Missense	proximal	-2	no	19.199	19.007	EPSD	COSMIC	8.808	Down-regulation
CMGC_CDK_CDK5_CDK5_ST	Q02078	MEF2A	Q00535	CDK5	S98	T103M	103	Missense	distal	5	no	16.877	16.673	EPSD	COSMIC	8.808	Down-regulation
CMGC_CDK_CDK5_CDK5_ST	Q02078	MEF2A	Q00535	CDK5	S98	R94G	94	Missense	distal	-4	no	16.877	16.497	EPSD	COSMIC;GDSC;CCLE	8.808	Down-regulation
CMGC_CDK_CDK5_CDK5_ST	Q02078	MEF2A	Q00535	CDK5	S98	G95A	95	Missense	distal	-3	no	16.877	16.871	EPSD	COSMIC	8.808	Down-regulation
CMGC_CDK_CDK5_CDK5_ST	Q02078	MEF2A	Q00535	CDK5	T108	T103M	103	Missense	distal	-5	no	17.738	17.481	EPSD	COSMIC	8.808	Down-regulation
CMGC_CDK_CDK5_CDK5_ST	Q02078	MEF2A	Q00535	CDK5	S181	S178N	178	Missense	distal	-3	no	17.456	17.438	EPSD	COSMIC	8.808	Down-regulation
CMGC_CDK_CDK5_CDK5_ST	Q02078	MEF2A	Q00535	CDK5	S181	S178R	178	Missense	distal	-3	no	17.456	17.470	EPSD	COSMIC	8.808	Up-regulation
CMGC_CDK_CDK5_CDK5_ST	Q02078	MEF2A	Q00535	CDK5	S192	G194R	194	Missense	proximal	2	no	17.180	17.353	EPSD	COSMIC	8.808	Up-regulation
CMGC_CDK_CDK5_CDK5_ST	Q02078	MEF2A	Q00535	CDK5	S192	Q197E	197	Missense	distal	5	no	17.180	17.129	EPSD	COSMIC	8.808	Down-regulation
CMGC_CDK_CDK5_CDK5_ST	Q02078	MEF2A	Q00535	CDK5	S223	P224A	224	Missense	proximal	1	no	17.690	6.664	EPSD	COSMIC	8.808	Loss
CMGC_CDK_CDK5_CDK5_ST	Q02078	MEF2A	Q00535	CDK5	S223	G221E	221	Missense	proximal	-2	no	17.690	17.713	EPSD	COSMIC	8.808	Up-regulation
CMGC_CDK_CDK5_CDK5_ST	Q02078	MEF2A	Q00535	CDK5	S223	G219E	219	Missense	distal	-4	no	17.690	17.903	EPSD	COSMIC	8.808	Up-regulation
CMGC_CDK_CDK5_CDK5_ST	Q02078	MEF2A	Q00535	CDK5	S235	P236L	236	Missense	proximal	1	no	17.057	5.107	EPSD	COSMIC	8.808	Loss
CMGC_CDK_CDK5_CDK5_ST	Q02078	MEF2A	Q00535	CDK5	S235	T242A	242	Missense	distal	7	no	17.057	17.048	EPSD	COSMIC	8.808	Down-regulation
CMGC_CDK_CDK5_CDK5_ST	Q02078	MEF2A	Q00535	CDK5	S255	P256A	256	Missense	proximal	1	no	17.774	6.747	EPSD	COSMIC	8.808	Loss
CMGC_CDK_CDK5_CDK5_ST	Q02078	MEF2A	Q00535	CDK5	S268	L273V	273	Missense	distal	5	no	8.963	9.111	EPSD	COSMIC	8.808	Up-regulation
CMGC_CDK_CDK5_CDK5_ST	Q02078	MEF2A	Q00535	CDK5	S268	L264F	264	Missense	distal	-4	no	8.963	8.622	EPSD	COSMIC	8.808	Loss
CMGC_CDK_CDK5_CDK5_ST	Q02078	MEF2A	Q00535	CDK5	T319	P323L	323	Missense	distal	4	no	16.310	16.229	EPSD	COSMIC	8.808	Down-regulation
CMGC_CDK_CDK5_CDK5_ST	Q02078	MEF2A	Q00535	CDK5	S355	Q351P	351	Missense	distal	-4	no	16.708	16.833	EPSD	COSMIC	8.808	Up-regulation
CMGC_CDK_CDK5_CDK5_ST	Q02078	MEF2A	Q00535	CDK5	S355	Q351H	351	Missense	distal	-4	no	16.708	16.498	EPSD	COSMIC	8.808	Down-regulation
CMGC_CDK_CDK5_CDK5_ST	Q02078	MEF2A	Q00535	CDK5	T415	Q420P	420	Missense	distal	5	no	17.087	17.136	EPSD	COSMIC	8.808	Up-regulation
CMGC_CDK_CDK5_CDK5_ST	Q02078	MEF2A	Q00535	CDK5	S453	S453R	453	Missense	central	0	yes	16.506	0.000	EPSD	COSMIC	8.808	Loss
CMGC_CDK_CDK5_CDK5_ST	P41236	PPP1R2	Q00535	CDK5	S20	M25V	25	Missense	distal	5	no	8.800	8.966	EPSD	COSMIC	8.808	Gain
CMGC_CDK_CDK5_CDK5_ST	P41236	PPP1R2	Q00535	CDK5	S130	D128G	128	Missense	proximal	-2	no	17.182	17.051	EPSD	COSMIC	8.808	Down-regulation
CMGC_CDK_CDK5_CDK5_ST	P41236	PPP1R2	Q00535	CDK5	S130	E124V	124	Missense	distal	-6	no	17.182	17.224	EPSD	COSMIC	8.808	Up-regulation
CMGC_CDK_CDK5_CDK5_ST	P41236	PPP1R2	Q00535	CDK5	S188	E181K	181	Missense	distal	-7	no	9.014	9.077	EPSD	COSMIC	8.808	Up-regulation
CMGC_CDK_CDK5_CDK5_ST	O43464	HTRA2	Q00535	CDK5	T54	V50G	50	Missense	distal	-4	no	16.127	15.768	EPSD	COSMIC	8.808	Down-regulation
CMGC_CDK_CDK5_CDK5_ST	O43464	HTRA2	Q00535	CDK5	T54	W58C	58	Missense	distal	4	no	16.127	16.090	EPSD	COSMIC	8.808	Down-regulation
CMGC_CDK_CDK5_CDK5_ST	O43464	HTRA2	Q00535	CDK5	T101	T101N	101	Missense	central	0	yes	10.050	0.000	EPSD	COSMIC	8.808	Loss
CMGC_CDK_CDK5_CDK5_ST	O43464	HTRA2	Q00535	CDK5	S142	A141S	141	Missense	proximal	-1	no	18.958	18.964	EPSD	COSMIC	8.808	Up-regulation
CMGC_CDK_CDK5_CDK5_ST	O43464	HTRA2	Q00535	CDK5	S142	S137R	137	Missense	distal	-5	no	18.958	19.038	EPSD	COSMIC	8.808	Up-regulation
CMGC_CDK_CDK5_CDK5_ST	O43464	HTRA2	Q00535	CDK5	S142	P139Q	139	Missense	distal	-3	no	18.958	18.941	EPSD	COSMIC	8.808	Down-regulation
CMGC_CDK_CDK5_CDK5_ST	O43464	HTRA2	Q00535	CDK5	S400	G399S	399	Missense	proximal	-1	no	18.346	18.350	PhosphoSitePlus	COSMIC	8.808	Up-regulation
CMGC_CDK_CDK5_CDK5_ST	O43464	HTRA2	Q00535	CDK5	S435	A438T	438	Missense	distal	3	no	8.695	9.476	EPSD	COSMIC	8.808	Gain
CMGC_CDK_CDK5_CDK5_ST	O43464	HTRA2	Q00535	CDK5	T453	T457K	457	Missense	distal	4	no	17.781	17.848	EPSD	COSMIC	8.808	Up-regulation
CMGC_CDK_CDK5_CDK5_ST	O43464	HTRA2	Q00535	CDK5	T453	Y451C	451	Missense	proximal	-2	no	17.781	17.738	EPSD	COSMIC	8.808	Down-regulation
CMGC_CDK_CDK5_CDK5_ST	P29474	NOS3	Q00535	CDK5	T33	G27S	27	Missense	distal	-6	no	17.026	17.121	EPSD	COSMIC	8.808	Up-regulation
CMGC_CDK_CDK5_CDK5_ST	P29474	NOS3	Q00535	CDK5	T33	A35T	35	Missense	proximal	2	no	17.026	17.145	EPSD	COSMIC	8.808	Up-regulation
CMGC_CDK_CDK5_CDK5_ST	P29474	NOS3	Q00535	CDK5	T33	Q29P	29	Missense	distal	-4	no	17.026	17.152	EPSD	COSMIC	8.808	Up-regulation
CMGC_CDK_CDK5_CDK5_ST	P29474	NOS3	Q00535	CDK5	S39	A35T	35	Missense	distal	-4	no	8.650	9.050	EPSD	COSMIC	8.808	Gain
CMGC_CDK_CDK5_CDK5_ST	P29474	NOS3	Q00535	CDK5	S53	P54S	54	Missense	proximal	1	no	17.923	6.022	EPSD	COSMIC	8.808	Loss
CMGC_CDK_CDK5_CDK5_ST	P29474	NOS3	Q00535	CDK5	S53	S57Y	57	Missense	distal	4	no	17.923	17.837	EPSD	COSMIC	8.808	Down-regulation
CMGC_CDK_CDK5_CDK5_ST	P29474	NOS3	Q00535	CDK5	S53	H52L	52	Missense	proximal	-1	no	17.923	17.920	EPSD	COSMIC	8.808	Down-regulation
CMGC_CDK_CDK5_CDK5_ST	P29474	NOS3	Q00535	CDK5	S53	E51Q	51	Missense	proximal	-2	no	17.923	18.172	EPSD	COSMIC	8.808	Up-regulation
CMGC_CDK_CDK5_CDK5_ST	P29474	NOS3	Q00535	CDK5	S57	P54S	54	Missense	distal	-3	no	19.339	19.333	EPSD	COSMIC	8.808	Down-regulation
CMGC_CDK_CDK5_CDK5_ST	P29474	NOS3	Q00535	CDK5	S57	S57Y	57	Missense	central	0	yes	19.339	0.000	EPSD	COSMIC	8.808	Loss
CMGC_CDK_CDK5_CDK5_ST	P29474	NOS3	Q00535	CDK5	S57	H52L	52	Missense	distal	-5	no	19.339	19.211	EPSD	COSMIC	8.808	Down-regulation
CMGC_CDK_CDK5_CDK5_ST	P29474	NOS3	Q00535	CDK5	S57	E51Q	51	Missense	distal	-6	no	19.339	19.375	EPSD	COSMIC	8.808	Up-regulation
CMGC_CDK_CDK5_CDK5_ST	P29474	NOS3	Q00535	CDK5	T60	P54S	54	Missense	distal	-6	no	9.456	9.495	EPSD	COSMIC	8.808	Up-regulation
CMGC_CDK_CDK5_CDK5_ST	P29474	NOS3	Q00535	CDK5	T60	K67N	67	Missense	distal	7	no	9.456	9.445	EPSD	COSMIC	8.808	Down-regulation
CMGC_CDK_CDK5_CDK5_ST	P29474	NOS3	Q00535	CDK5	T60	S57Y	57	Missense	distal	-3	no	9.456	9.399	EPSD	COSMIC	8.808	Down-regulation
CMGC_CDK_CDK5_CDK5_ST	P29474	NOS3	Q00535	CDK5	S470	R474H	474	Missense	distal	4	no	15.797	15.757	EPSD	COSMIC	8.808	Down-regulation
CMGC_CDK_CDK5_CDK5_ST	P29474	NOS3	Q00535	CDK5	S470	N466S	466	Missense	distal	-4	no	15.797	16.309	EPSD	COSMIC	8.808	Up-regulation
CMGC_CDK_CDK5_CDK5_ST	P29474	NOS3	Q00535	CDK5	S470	R474C	474	Missense	distal	4	no	15.797	15.688	EPSD	COSMIC	8.808	Down-regulation
CMGC_CDK_CDK5_CDK5_ST	P29474	NOS3	Q00535	CDK5	S470	M464L	464	Missense	distal	-6	no	15.797	15.823	EPSD	COSMIC	8.808	Up-regulation
CMGC_CDK_CDK5_CDK5_ST	P29474	NOS3	Q00535	CDK5	S600	G595S	595	Missense	distal	-5	no	17.366	17.537	EPSD	COSMIC;GDSC;CCLE	8.808	Up-regulation
CMGC_CDK_CDK5_CDK5_ST	P29474	NOS3	Q00535	CDK5	S600	R602W	602	Missense	proximal	2	no	17.366	17.174	EPSD	COSMIC	8.808	Down-regulation
CMGC_CDK_CDK5_CDK5_ST	P29474	NOS3	Q00535	CDK5	S600	S594F	594	Missense	distal	-6	no	17.366	17.193	EPSD	COSMIC	8.808	Down-regulation
CMGC_CDK_CDK5_CDK5_ST	P29474	NOS3	Q00535	CDK5	S634	D637H	637	Missense	distal	3	no	8.358	9.371	EPSD	COSMIC	8.808	Gain
CMGC_CDK_CDK5_CDK5_ST	P29474	NOS3	Q00535	CDK5	S725	A719T	719	Missense	distal	-6	no	20.256	20.342	EPSD	COSMIC	8.808	Up-regulation
CMGC_CDK_CDK5_CDK5_ST	P29474	NOS3	Q00535	CDK5	S870	R875Q	875	Missense	distal	5	no	16.752	16.627	EPSD	COSMIC	8.808	Down-regulation
CMGC_CDK_CDK5_CDK5_ST	P29474	NOS3	Q00535	CDK5	S981	G986E	986	Missense	distal	5	no	10.918	10.909	EPSD	COSMIC	8.808	Down-regulation
CMGC_CDK_CDK5_CDK5_ST	P29474	NOS3	Q00535	CDK5	S1202	S1198L	1198	Missense	distal	-4	no	17.278	16.458	EPSD	COSMIC	8.808	Down-regulation
CMGC_CDK_CDK5_CDK5_ST	P26358	DNMT1	Q00535	CDK5	S127	P128T	128	Missense	proximal	1	no	18.776	8.289	EPSD	COSMIC;GDSC	8.808	Loss
CMGC_CDK_CDK5_CDK5_ST	P26358	DNMT1	Q00535	CDK5	S127	S133F	133	Missense	distal	6	no	18.776	18.756	EPSD	COSMIC	8.808	Down-regulation
CMGC_CDK_CDK5_CDK5_ST	P26358	DNMT1	Q00535	CDK5	S127	P129L	129	Missense	proximal	2	no	18.776	18.611	EPSD	COSMIC	8.808	Down-regulation
CMGC_CDK_CDK5_CDK5_ST	P26358	DNMT1	Q00535	CDK5	S127	L132P	132	Missense	distal	5	no	18.776	18.949	EPSD	COSMIC	8.808	Up-regulation
CMGC_CDK_CDK5_CDK5_ST	P26358	DNMT1	Q00535	CDK5	S127	D124C	124	Missense	distal	-3	no	18.776	18.753	EPSD	COSMIC	8.808	Down-regulation
CMGC_CDK_CDK5_CDK5_ST	P26358	DNMT1	Q00535	CDK5	T137	S133F	133	Missense	distal	-4	no	19.519	18.358	EPSD	COSMIC	8.808	Down-regulation
CMGC_CDK_CDK5_CDK5_ST	P26358	DNMT1	Q00535	CDK5	T137	R140K	140	Missense	distal	3	no	19.519	19.839	EPSD	COSMIC	8.808	Up-regulation
CMGC_CDK_CDK5_CDK5_ST	P26358	DNMT1	Q00535	CDK5	T137	R136C	136	Missense	proximal	-1	no	19.519	19.513	EPSD	COSMIC	8.808	Down-regulation
CMGC_CDK_CDK5_CDK5_ST	P26358	DNMT1	Q00535	CDK5	T137	L132P	132	Missense	distal	-5	no	19.519	19.717	EPSD	COSMIC	8.808	Up-regulation
CMGC_CDK_CDK5_CDK5_ST	P26358	DNMT1	Q00535	CDK5	T137	D144N	144	Missense	distal	7	no	19.519	19.524	EPSD	COSMIC	8.808	Up-regulation
CMGC_CDK_CDK5_CDK5_ST	P26358	DNMT1	Q00535	CDK5	S152	S154C	154	Missense	proximal	2	no	18.160	17.992	EPSD	COSMIC	8.808	Down-regulation
CMGC_CDK_CDK5_CDK5_ST	P26358	DNMT1	Q00535	CDK5	S154	S161G	161	Missense	distal	7	no	17.369	17.359	PhosphoSitePlus	COSMIC	8.808	Down-regulation
CMGC_CDK_CDK5_CDK5_ST	P26358	DNMT1	Q00535	CDK5	S154	S154C	154	Missense	central	0	yes	17.369	0.000	PhosphoSitePlus	COSMIC	8.808	Loss
CMGC_CDK_CDK5_CDK5_ST	P26358	DNMT1	Q00535	CDK5	T162	I167F	167	Missense	distal	5	no	8.887	8.738	EPSD	COSMIC	8.808	Loss
CMGC_CDK_CDK5_CDK5_ST	P26358	DNMT1	Q00535	CDK5	T162	T166I	166	Missense	distal	4	no	8.887	8.846	EPSD	COSMIC	8.808	Down-regulation
CMGC_CDK_CDK5_CDK5_ST	P26358	DNMT1	Q00535	CDK5	T162	S161G	161	Missense	proximal	-1	no	8.887	8.882	EPSD	COSMIC	8.808	Down-regulation
CMGC_CDK_CDK5_CDK5_ST	P26358	DNMT1	Q00535	CDK5	T162	T165I	165	Missense	distal	3	no	8.887	7.909	EPSD	COSMIC	8.808	Loss
CMGC_CDK_CDK5_CDK5_ST	P26358	DNMT1	Q00535	CDK5	S209	R215T	215	Missense	distal	6	no	9.948	9.941	EPSD	COSMIC;CCLE	8.808	Down-regulation
CMGC_CDK_CDK5_CDK5_ST	P26358	DNMT1	Q00535	CDK5	S209	P216L	216	Missense	distal	7	no	9.948	9.936	EPSD	COSMIC	8.808	Down-regulation
CMGC_CDK_CDK5_CDK5_ST	P26358	DNMT1	Q00535	CDK5	S209	R205H	205	Missense	distal	-4	no	9.948	9.728	EPSD	COSMIC	8.808	Down-regulation
CMGC_CDK_CDK5_CDK5_ST	P26358	DNMT1	Q00535	CDK5	S209	P216Q	216	Missense	distal	7	no	9.948	9.944	EPSD	COSMIC	8.808	Down-regulation
CMGC_CDK_CDK5_CDK5_ST	P26358	DNMT1	Q00535	CDK5	S209	R215K	215	Missense	distal	6	no	9.948	9.950	EPSD	COSMIC	8.808	Up-regulation
CMGC_CDK_CDK5_CDK5_ST	P26358	DNMT1	Q00535	CDK5	S247	P252L	252	Missense	distal	5	no	10.675	10.502	EPSD	COSMIC	8.808	Down-regulation
CMGC_CDK_CDK5_CDK5_ST	P26358	DNMT1	Q00535	CDK5	S247	R246Q	246	Missense	proximal	-1	no	10.675	10.673	EPSD	COSMIC	8.808	Down-regulation
CMGC_CDK_CDK5_CDK5_ST	P26358	DNMT1	Q00535	CDK5	S247	P254H	254	Missense	distal	7	no	10.675	10.671	EPSD	COSMIC	8.808	Down-regulation
CMGC_CDK_CDK5_CDK5_ST	P26358	DNMT1	Q00535	CDK5	S247	R246C	246	Missense	proximal	-1	no	10.675	10.669	EPSD	COSMIC	8.808	Down-regulation
CMGC_CDK_CDK5_CDK5_ST	P26358	DNMT1	Q00535	CDK5	S247	R246H	246	Missense	proximal	-1	no	10.675	10.673	EPSD	COSMIC	8.808	Down-regulation
CMGC_CDK_CDK5_CDK5_ST	P26358	DNMT1	Q00535	CDK5	T253	P252L	252	Missense	proximal	-1	no	16.979	16.974	EPSD	COSMIC	8.808	Down-regulation
CMGC_CDK_CDK5_CDK5_ST	P26358	DNMT1	Q00535	CDK5	T253	R246Q	246	Missense	distal	-7	no	16.979	16.959	EPSD	COSMIC	8.808	Down-regulation
CMGC_CDK_CDK5_CDK5_ST	P26358	DNMT1	Q00535	CDK5	T253	P254H	254	Missense	proximal	1	no	16.979	-1.534	EPSD	COSMIC	8.808	Loss
CMGC_CDK_CDK5_CDK5_ST	P26358	DNMT1	Q00535	CDK5	T253	R246C	246	Missense	distal	-7	no	16.979	16.907	EPSD	COSMIC	8.808	Down-regulation
CMGC_CDK_CDK5_CDK5_ST	P26358	DNMT1	Q00535	CDK5	T253	R246H	246	Missense	distal	-7	no	16.979	16.947	EPSD	COSMIC	8.808	Down-regulation
CMGC_CDK_CDK5_CDK5_ST	P26358	DNMT1	Q00535	CDK5	S288	K291N	291	Missense	distal	3	no	10.524	8.591	EPSD	COSMIC	8.808	Loss
CMGC_CDK_CDK5_CDK5_ST	P26358	DNMT1	Q00535	CDK5	S288	R287K	287	Missense	proximal	-1	no	10.524	10.526	EPSD	COSMIC	8.808	Up-regulation
CMGC_CDK_CDK5_CDK5_ST	P26358	DNMT1	Q00535	CDK5	S288	D282Y	282	Missense	distal	-6	no	10.524	10.488	EPSD	COSMIC	8.808	Down-regulation
CMGC_CDK_CDK5_CDK5_ST	P26358	DNMT1	Q00535	CDK5	S288	Q289E	289	Missense	proximal	1	no	10.524	-2.711	EPSD	COSMIC	8.808	Loss
CMGC_CDK_CDK5_CDK5_ST	P26358	DNMT1	Q00535	CDK5	S288	S288N	288	Missense	central	0	yes	10.524	0.000	EPSD	COSMIC	8.808	Loss
CMGC_CDK_CDK5_CDK5_ST	P26358	DNMT1	Q00535	CDK5	S288	K284Q	284	Missense	distal	-4	no	10.524	10.178	EPSD	COSMIC	8.808	Down-regulation
CMGC_CDK_CDK5_CDK5_ST	P26358	DNMT1	Q00535	CDK5	S288	D282N	282	Missense	distal	-6	no	10.524	10.563	EPSD	COSMIC	8.808	Up-regulation
CMGC_CDK_CDK5_CDK5_ST	P26358	DNMT1	Q00535	CDK5	T328	R325H	325	Missense	distal	-3	no	17.001	16.969	EPSD	COSMIC	8.808	Down-regulation
CMGC_CDK_CDK5_CDK5_ST	P26358	DNMT1	Q00535	CDK5	T328	R325L	325	Missense	distal	-3	no	17.001	16.931	EPSD	COSMIC	8.808	Down-regulation
CMGC_CDK_CDK5_CDK5_ST	P26358	DNMT1	Q00535	CDK5	T328	P332L	332	Missense	distal	4	no	17.001	16.919	EPSD	COSMIC	8.808	Down-regulation
CMGC_CDK_CDK5_CDK5_ST	P26358	DNMT1	Q00535	CDK5	T328	E321G	321	Missense	distal	-7	no	17.001	16.994	EPSD	COSMIC	8.808	Down-regulation
CMGC_CDK_CDK5_CDK5_ST	P26358	DNMT1	Q00535	CDK5	S714	P710S	710	Missense	distal	-4	no	19.235	19.581	EPSD	COSMIC	8.808	Up-regulation
CMGC_CDK_CDK5_CDK5_ST	P26358	DNMT1	Q00535	CDK5	S714	M712T	712	Missense	proximal	-2	no	19.235	19.668	EPSD	COSMIC;GDSC	8.808	Up-regulation
CMGC_CDK_CDK5_CDK5_ST	P26358	DNMT1	Q00535	CDK5	S714	M712L	712	Missense	proximal	-2	no	19.235	19.393	EPSD	COSMIC	8.808	Up-regulation
CMGC_CDK_CDK5_CDK5_ST	P26358	DNMT1	Q00535	CDK5	S878	P879S	879	Missense	proximal	1	no	18.929	7.027	EPSD	COSMIC;CCLE	8.808	Loss
CMGC_CDK_CDK5_CDK5_ST	P26358	DNMT1	Q00535	CDK5	S878	E877K	877	Missense	proximal	-1	no	18.929	18.934	EPSD	COSMIC	8.808	Up-regulation
CMGC_CDK_CDK5_CDK5_ST	P26358	DNMT1	Q00535	CDK5	S878	T882I	882	Missense	distal	4	no	18.929	18.887	EPSD	COSMIC	8.808	Down-regulation
CMGC_CDK_CDK5_CDK5_ST	P26358	DNMT1	Q00535	CDK5	T882	P879S	879	Missense	distal	-3	no	10.004	9.999	EPSD	COSMIC;CCLE	8.808	Down-regulation
CMGC_CDK_CDK5_CDK5_ST	P26358	DNMT1	Q00535	CDK5	T882	E877K	877	Missense	distal	-5	no	10.004	10.294	EPSD	COSMIC	8.808	Up-regulation
CMGC_CDK_CDK5_CDK5_ST	P26358	DNMT1	Q00535	CDK5	T882	T882I	882	Missense	central	0	yes	10.004	0.000	EPSD	COSMIC	8.808	Loss
CMGC_CDK_CDK5_CDK5_ST	P26358	DNMT1	Q00535	CDK5	S954	R958C	958	Missense	distal	4	no	19.576	19.467	EPSD	COSMIC	8.808	Down-regulation
CMGC_CDK_CDK5_CDK5_ST	P26358	DNMT1	Q00535	CDK5	S954	P955L	955	Missense	proximal	1	no	19.576	7.626	EPSD	COSMIC	8.808	Loss
CMGC_CDK_CDK5_CDK5_ST	P26358	DNMT1	Q00535	CDK5	S954	K961N	961	Missense	distal	7	no	19.576	19.564	EPSD	COSMIC	8.808	Down-regulation
CMGC_CDK_CDK5_CDK5_ST	P26358	DNMT1	Q00535	CDK5	S954	R960Q	960	Missense	distal	6	no	19.576	19.565	EPSD	COSMIC	8.808	Down-regulation
CMGC_CDK_CDK5_CDK5_ST	P26358	DNMT1	Q00535	CDK5	S954	K951R	951	Missense	distal	-3	no	19.576	19.556	EPSD	COSMIC	8.808	Down-regulation
CMGC_CDK_CDK5_CDK5_ST	P26358	DNMT1	Q00535	CDK5	S954	R958H	958	Missense	distal	4	no	19.576	19.536	EPSD	COSMIC	8.808	Down-regulation
CMGC_CDK_CDK5_CDK5_ST	P26358	DNMT1	Q00535	CDK5	S954	P959S	959	Missense	distal	5	no	19.576	19.588	EPSD	COSMIC	8.808	Up-regulation
CMGC_CDK_CDK5_CDK5_ST	P26358	DNMT1	Q00535	CDK5	S954	T947M	947	Missense	distal	-7	no	19.576	19.518	EPSD	COSMIC	8.808	Down-regulation
CMGC_CDK_CDK5_CDK5_ST	P26358	DNMT1	Q00535	CDK5	S954	I950M	950	Missense	distal	-4	no	19.576	19.121	EPSD	COSMIC	8.808	Down-regulation
CMGC_CDK_CDK5_CDK5_ST	P26358	DNMT1	Q00535	CDK5	S1105	N1101K	1101	Missense	distal	-4	no	18.070	18.458	EPSD	COSMIC	8.808	Up-regulation
CMGC_CDK_CDK5_CDK5_ST	P26358	DNMT1	Q00535	CDK5	S1105	D1098V	1098	Missense	distal	-7	no	18.070	18.095	EPSD	COSMIC	8.808	Up-regulation
CMGC_CDK_CDK5_CDK5_ST	P26358	DNMT1	Q00535	CDK5	S1105	R1104C	1104	Missense	proximal	-1	no	18.070	18.063	EPSD	COSMIC	8.808	Down-regulation
CMGC_CDK_CDK5_CDK5_ST	P26358	DNMT1	Q00535	CDK5	S1105	P1106L	1106	Missense	proximal	1	no	18.070	6.120	EPSD	COSMIC	8.808	Loss
CMGC_CDK_CDK5_CDK5_ST	P26358	DNMT1	Q00535	CDK5	S1122	Q1123P	1123	Missense	proximal	1	no	8.106	17.082	EPSD	COSMIC	8.808	Gain
CMGC_CDK_CDK5_CDK5_ST	P26358	DNMT1	Q00535	CDK5	T1204	R1207C	1207	Missense	distal	3	no	9.077	6.781	EPSD	COSMIC	8.808	Loss
CMGC_CDK_CDK5_CDK5_ST	P26358	DNMT1	Q00535	CDK5	T1204	R1210W	1210	Missense	distal	6	no	9.077	9.060	EPSD	COSMIC	8.808	Down-regulation
CMGC_CDK_CDK5_CDK5_ST	P26358	DNMT1	Q00535	CDK5	T1204	R1210Q	1210	Missense	distal	6	no	9.077	9.066	EPSD	COSMIC	8.808	Down-regulation
CMGC_CDK_CDK5_CDK5_ST	P26358	DNMT1	Q00535	CDK5	T1204	R1207H	1207	Missense	distal	3	no	9.077	8.057	EPSD	COSMIC	8.808	Loss
CMGC_CDK_CDK5_CDK5_ST	P26358	DNMT1	Q00535	CDK5	T1204	G1208N	1208	Missense	distal	4	no	9.077	9.097	EPSD	COSMIC	8.808	Up-regulation
CMGC_CDK_CDK5_CDK5_ST	P26358	DNMT1	Q00535	CDK5	T1204	T1204A	1204	Missense	central	0	yes	9.077	0.000	EPSD	COSMIC	8.808	Loss
CMGC_CDK_CDK5_CDK5_ST	P26358	DNMT1	Q00535	CDK5	T1204	S1206C	1206	Missense	proximal	2	no	9.077	8.909	EPSD	COSMIC	8.808	Down-regulation
CMGC_CDK_CDK5_CDK5_ST	P26358	DNMT1	Q00535	CDK5	T1204	S1206F	1206	Missense	proximal	2	no	9.077	8.867	EPSD	COSMIC	8.808	Down-regulation
CMGC_CDK_CDK5_CDK5_ST	Q13315	ATM	Q00535	CDK5	S47	L43P	43	Missense	distal	-4	no	8.575	9.048	EPSD	COSMIC	8.808	Gain
CMGC_CDK_CDK5_CDK5_ST	Q13315	ATM	Q00535	CDK5	T86	A84V	84	Missense	proximal	-2	no	8.664	8.860	EPSD	COSMIC	8.808	Gain
CMGC_CDK_CDK5_CDK5_ST	Q13315	ATM	Q00535	CDK5	S89	M94I	94	Missense	distal	5	no	11.716	11.830	EPSD	COSMIC	8.808	Up-regulation
CMGC_CDK_CDK5_CDK5_ST	Q13315	ATM	Q00535	CDK5	S89	A88V	88	Missense	proximal	-1	no	11.716	11.720	EPSD	COSMIC	8.808	Up-regulation
CMGC_CDK_CDK5_CDK5_ST	Q13315	ATM	Q00535	CDK5	S89	Q95K	95	Missense	distal	6	no	11.716	11.729	EPSD	COSMIC	8.808	Up-regulation
CMGC_CDK_CDK5_CDK5_ST	Q13315	ATM	Q00535	CDK5	S89	M94V	94	Missense	distal	5	no	11.716	11.883	EPSD	COSMIC	8.808	Up-regulation
CMGC_CDK_CDK5_CDK5_ST	Q13315	ATM	Q00535	CDK5	S89	S83L	83	Missense	distal	-6	no	11.716	11.594	EPSD	COSMIC	8.808	Down-regulation
CMGC_CDK_CDK5_CDK5_ST	Q13315	ATM	Q00535	CDK5	S89	A84V	84	Missense	distal	-5	no	11.716	11.841	EPSD	COSMIC	8.808	Up-regulation
CMGC_CDK_CDK5_CDK5_ST	Q13315	ATM	Q00535	CDK5	T297	P292R	292	Missense	distal	-5	no	10.053	10.156	EPSD	COSMIC	8.808	Up-regulation
CMGC_CDK_CDK5_CDK5_ST	Q13315	ATM	Q00535	CDK5	T297	G294E	294	Missense	distal	-3	no	10.053	10.056	EPSD	COSMIC	8.808	Up-regulation
CMGC_CDK_CDK5_CDK5_ST	Q13315	ATM	Q00535	CDK5	T297	H290L	290	Missense	distal	-7	no	10.053	10.028	EPSD	COSMIC	8.808	Down-regulation
CMGC_CDK_CDK5_CDK5_ST	Q13315	ATM	Q00535	CDK5	T297	H291R	291	Missense	distal	-6	no	10.053	10.119	EPSD	COSMIC;GDSC;CCLE	8.808	Up-regulation
CMGC_CDK_CDK5_CDK5_ST	Q13315	ATM	Q00535	CDK5	T297	G301C	301	Missense	distal	4	no	10.053	10.012	EPSD	COSMIC	8.808	Down-regulation
CMGC_CDK_CDK5_CDK5_ST	Q13315	ATM	Q00535	CDK5	T297	E304G	304	Missense	distal	7	no	10.053	10.052	EPSD	COSMIC	8.808	Down-regulation
CMGC_CDK_CDK5_CDK5_ST	Q13315	ATM	Q00535	CDK5	S305	W308R	308	Missense	distal	3	no	7.293	8.984	EPSD	COSMIC	8.808	Gain
CMGC_CDK_CDK5_CDK5_ST	Q13315	ATM	Q00535	CDK5	T373	Y380N	380	Missense	distal	7	no	9.053	9.062	EPSD	COSMIC	8.808	Up-regulation
CMGC_CDK_CDK5_CDK5_ST	Q13315	ATM	Q00535	CDK5	T373	T372A	372	Missense	proximal	-1	no	9.053	9.049	EPSD	COSMIC	8.808	Down-regulation
CMGC_CDK_CDK5_CDK5_ST	Q13315	ATM	Q00535	CDK5	S794	K793R	793	Missense	proximal	-1	no	19.473	19.471	PhosphoSitePlus	COSMIC	8.808	Down-regulation
CMGC_CDK_CDK5_CDK5_ST	Q13315	ATM	Q00535	CDK5	S794	A799T	799	Missense	distal	5	no	19.473	19.607	PhosphoSitePlus	COSMIC	8.808	Up-regulation
CMGC_CDK_CDK5_CDK5_ST	Q13315	ATM	Q00535	CDK5	S794	T791N	791	Missense	distal	-3	no	19.473	19.457	PhosphoSitePlus	COSMIC	8.808	Down-regulation
CMGC_CDK_CDK5_CDK5_ST	Q13315	ATM	Q00535	CDK5	S794	K792N	792	Missense	proximal	-2	no	19.473	19.289	PhosphoSitePlus	COSMIC	8.808	Down-regulation
CMGC_CDK_CDK5_CDK5_ST	Q13315	ATM	Q00535	CDK5	S794	A799V	799	Missense	distal	5	no	19.473	19.570	PhosphoSitePlus	COSMIC	8.808	Up-regulation
CMGC_CDK_CDK5_CDK5_ST	Q13315	ATM	Q00535	CDK5	S1105	P1112H	1112	Missense	distal	7	no	9.089	9.084	EPSD	COSMIC	8.808	Down-regulation
CMGC_CDK_CDK5_CDK5_ST	Q13315	ATM	Q00535	CDK5	S1105	L1111P	1111	Missense	distal	6	no	9.089	9.103	EPSD	COSMIC	8.808	Up-regulation
CMGC_CDK_CDK5_CDK5_ST	Q13315	ATM	Q00535	CDK5	S1770	Y1763C	1763	Missense	distal	-7	no	11.116	11.109	EPSD	COSMIC	8.808	Down-regulation
CMGC_CDK_CDK5_CDK5_ST	Q13315	ATM	Q00535	CDK5	S1770	L1764V	1764	Missense	distal	-6	no	11.116	11.193	EPSD	COSMIC	8.808	Up-regulation
CMGC_CDK_CDK5_CDK5_ST	Q13315	ATM	Q00535	CDK5	S1770	P1766L	1766	Missense	distal	-4	no	11.116	10.643	EPSD	COSMIC	8.808	Down-regulation
CMGC_CDK_CDK5_CDK5_ST	Q13315	ATM	Q00535	CDK5	S1770	R1768T	1768	Missense	proximal	-2	no	11.116	11.031	EPSD	COSMIC	8.808	Down-regulation
CMGC_CDK_CDK5_CDK5_ST	Q13315	ATM	Q00535	CDK5	S1770	S1770L	1770	Missense	central	0	yes	11.116	0.000	EPSD	COSMIC	8.808	Loss
CMGC_CDK_CDK5_CDK5_ST	Q13315	ATM	Q00535	CDK5	S1878	T1880R	1880	Missense	proximal	2	no	8.745	8.820	EPSD	COSMIC	8.808	Gain
CMGC_CDK_CDK5_CDK5_ST	Q13315	ATM	Q00535	CDK5	S1881	F1877L	1877	Missense	distal	-4	no	8.720	9.061	EPSD	COSMIC	8.808	Gain
CMGC_CDK_CDK5_CDK5_ST	Q13315	ATM	Q00535	CDK5	S1881	F1877Y	1877	Missense	distal	-4	no	8.720	8.900	EPSD	COSMIC	8.808	Gain
CMGC_CDK_CDK5_CDK5_ST	Q13315	ATM	Q00535	CDK5	T1885	T1880R	1880	Missense	distal	-5	no	17.580	17.686	EPSD	COSMIC	8.808	Up-regulation
CMGC_CDK_CDK5_CDK5_ST	Q13315	ATM	Q00535	CDK5	S1981	I1986M	1986	Missense	distal	5	no	9.165	9.051	EPSD	COSMIC	8.808	Down-regulation
CMGC_CDK_CDK5_CDK5_ST	Q13315	ATM	Q00535	CDK5	S1981	A1976S	1976	Missense	distal	-5	no	9.165	9.347	EPSD	COSMIC	8.808	Up-regulation
CMGC_CDK_CDK5_CDK5_ST	Q13315	ATM	Q00535	CDK5	S1981	Q1982K	1982	Missense	proximal	1	no	9.165	-0.037	EPSD	COSMIC	8.808	Loss
CMGC_CDK_CDK5_CDK5_ST	Q13315	ATM	Q00535	CDK5	S1981	G1980R	1980	Missense	proximal	-1	no	9.165	9.170	EPSD	COSMIC	8.808	Up-regulation
CMGC_CDK_CDK5_CDK5_ST	Q13315	ATM	Q00535	CDK5	S1981	E1978V	1978	Missense	distal	-3	no	9.165	9.195	EPSD	COSMIC	8.808	Up-regulation
CMGC_CDK_CDK5_CDK5_ST	Q13315	ATM	Q00535	CDK5	S1981	S1983C	1983	Missense	proximal	2	no	9.165	8.998	EPSD	COSMIC	8.808	Down-regulation
CMGC_CDK_CDK5_CDK5_ST	Q13315	ATM	Q00535	CDK5	T2031	R2034P	2034	Missense	distal	3	no	9.258	7.859	EPSD	COSMIC	8.808	Loss
CMGC_CDK_CDK5_CDK5_ST	Q13315	ATM	Q00535	CDK5	T2031	I2030V	2030	Missense	proximal	-1	no	9.258	9.259	EPSD	COSMIC	8.808	Up-regulation
CMGC_CDK_CDK5_CDK5_ST	Q13315	ATM	Q00535	CDK5	T2031	G2024R	2024	Missense	distal	-7	no	9.258	9.310	EPSD	COSMIC	8.808	Up-regulation
CMGC_CDK_CDK5_CDK5_ST	Q13315	ATM	Q00535	CDK5	T2031	R2032T	2032	Missense	proximal	1	no	9.258	7.718	EPSD	COSMIC	8.808	Loss
CMGC_CDK_CDK5_CDK5_ST	Q13315	ATM	Q00535	CDK5	T2031	H2038R	2038	Missense	distal	7	no	9.258	9.264	EPSD	COSMIC	8.808	Up-regulation
CMGC_CDK_CDK5_CDK5_ST	Q13315	ATM	Q00535	CDK5	T2031	L2033I	2033	Missense	proximal	2	no	9.258	9.335	EPSD	COSMIC	8.808	Up-regulation
CMGC_CDK_CDK5_CDK5_ST	Q13315	ATM	Q00535	CDK5	T2031	Y2036N	2036	Missense	distal	5	no	9.258	9.371	EPSD	COSMIC	8.808	Up-regulation
CMGC_CDK_CDK5_CDK5_ST	Q13315	ATM	Q00535	CDK5	T2031	G2024E	2024	Missense	distal	-7	no	9.258	9.264	EPSD	COSMIC	8.808	Up-regulation
CMGC_CDK_CDK5_CDK5_ST	Q13315	ATM	Q00535	CDK5	T2031	G2024W	2024	Missense	distal	-7	no	9.258	9.260	EPSD	COSMIC	8.808	Up-regulation
CMGC_CDK_CDK5_CDK5_ST	Q13315	ATM	Q00535	CDK5	S2242	E2245K	2245	Missense	distal	3	no	8.344	10.630	EPSD	COSMIC	8.808	Gain
CMGC_CDK_CDK5_CDK5_ST	Q13315	ATM	Q00535	CDK5	S2242	E2238K	2238	Missense	distal	-4	no	8.344	8.847	EPSD	COSMIC	8.808	Gain
CMGC_CDK_CDK5_CDK5_ST	Q13315	ATM	Q00535	CDK5	S2592	D2597H	2597	Missense	distal	5	no	8.806	8.899	EPSD	COSMIC	8.808	Gain
CMGC_CDK_CDK5_CDK5_ST	Q13315	ATM	Q00535	CDK5	S2592	Q2593R	2593	Missense	proximal	1	no	8.806	8.835	EPSD	COSMIC	8.808	Gain
CMGC_CDK_CDK5_CDK5_ST	Q9UQL6	HDAC5	Q00535	CDK5	S3	E6K	6	Missense	distal	3	no	16.820	19.106	EPSD	COSMIC	8.808	Up-regulation
CMGC_CDK_CDK5_CDK5_ST	Q9UQL6	HDAC5	Q00535	CDK5	S53	R60W	60	Missense	distal	7	no	16.933	16.922	EPSD	COSMIC	8.808	Down-regulation
CMGC_CDK_CDK5_CDK5_ST	Q9UQL6	HDAC5	Q00535	CDK5	S53	P54S	54	Missense	proximal	1	no	16.933	5.032	EPSD	COSMIC	8.808	Loss
CMGC_CDK_CDK5_CDK5_ST	Q9UQL6	HDAC5	Q00535	CDK5	S53	R60L	60	Missense	distal	7	no	16.933	16.919	EPSD	COSMIC	8.808	Down-regulation
CMGC_CDK_CDK5_CDK5_ST	Q9UQL6	HDAC5	Q00535	CDK5	S53	G51E	51	Missense	proximal	-2	no	16.933	16.956	EPSD	COSMIC	8.808	Up-regulation
CMGC_CDK_CDK5_CDK5_ST	Q9UQL6	HDAC5	Q00535	CDK5	S55	R60W	60	Missense	distal	5	no	16.748	16.571	EPSD	COSMIC	8.808	Down-regulation
CMGC_CDK_CDK5_CDK5_ST	Q9UQL6	HDAC5	Q00535	CDK5	S55	P54S	54	Missense	proximal	-1	no	16.748	16.750	EPSD	COSMIC	8.808	Up-regulation
CMGC_CDK_CDK5_CDK5_ST	Q9UQL6	HDAC5	Q00535	CDK5	S55	R60L	60	Missense	distal	5	no	16.748	16.501	EPSD	COSMIC	8.808	Down-regulation
CMGC_CDK_CDK5_CDK5_ST	Q9UQL6	HDAC5	Q00535	CDK5	S55	G51E	51	Missense	distal	-4	no	16.748	16.962	EPSD	COSMIC	8.808	Up-regulation
CMGC_CDK_CDK5_CDK5_ST	Q9UQL6	HDAC5	Q00535	CDK5	T199	G202S	202	Missense	distal	3	no	17.440	17.404	EPSD	COSMIC	8.808	Down-regulation
CMGC_CDK_CDK5_CDK5_ST	Q9UQL6	HDAC5	Q00535	CDK5	T199	S193L	193	Missense	distal	-6	no	17.440	17.318	EPSD	COSMIC	8.808	Down-regulation
CMGC_CDK_CDK5_CDK5_ST	Q9UQL6	HDAC5	Q00535	CDK5	T199	K196N	196	Missense	distal	-3	no	17.440	17.388	EPSD	COSMIC	8.808	Down-regulation
CMGC_CDK_CDK5_CDK5_ST	Q9UQL6	HDAC5	Q00535	CDK5	S225	L221F	221	Missense	distal	-4	no	16.755	16.413	EPSD	COSMIC	8.808	Down-regulation
CMGC_CDK_CDK5_CDK5_ST	Q9UQL6	HDAC5	Q00535	CDK5	S225	G230A	230	Missense	distal	5	no	16.755	16.724	EPSD	COSMIC	8.808	Down-regulation
CMGC_CDK_CDK5_CDK5_ST	Q9UQL6	HDAC5	Q00535	CDK5	S225	P232L	232	Missense	distal	7	no	16.755	16.743	EPSD	COSMIC	8.808	Down-regulation
CMGC_CDK_CDK5_CDK5_ST	Q9UQL6	HDAC5	Q00535	CDK5	S225	G230R	230	Missense	distal	5	no	16.755	16.922	EPSD	COSMIC;CCLE	8.808	Up-regulation
CMGC_CDK_CDK5_CDK5_ST	Q9UQL6	HDAC5	Q00535	CDK5	S225	G230D	230	Missense	distal	5	no	16.755	16.726	EPSD	COSMIC;CCLE	8.808	Down-regulation
CMGC_CDK_CDK5_CDK5_ST	Q9UQL6	HDAC5	Q00535	CDK5	S225	G230S	230	Missense	distal	5	no	16.755	16.859	EPSD	COSMIC	8.808	Up-regulation
CMGC_CDK_CDK5_CDK5_ST	Q9UQL6	HDAC5	Q00535	CDK5	S225	P232T	232	Missense	distal	7	no	16.755	16.754	EPSD	COSMIC	8.808	Down-regulation
CMGC_CDK_CDK5_CDK5_ST	Q9UQL6	HDAC5	Q00535	CDK5	S229	G230R	230	Missense	proximal	1	no	-2.719	9.750	EPSD	COSMIC;CCLE	8.808	Gain
CMGC_CDK_CDK5_CDK5_ST	Q9UQL6	HDAC5	Q00535	CDK5	T234	G230A	230	Missense	distal	-4	no	17.559	17.498	EPSD	COSMIC	8.808	Down-regulation
CMGC_CDK_CDK5_CDK5_ST	Q9UQL6	HDAC5	Q00535	CDK5	T234	P232L	232	Missense	proximal	-2	no	17.559	17.144	EPSD	COSMIC	8.808	Down-regulation
CMGC_CDK_CDK5_CDK5_ST	Q9UQL6	HDAC5	Q00535	CDK5	T234	G230R	230	Missense	distal	-4	no	17.559	17.938	EPSD	COSMIC;CCLE	8.808	Up-regulation
CMGC_CDK_CDK5_CDK5_ST	Q9UQL6	HDAC5	Q00535	CDK5	T234	G230D	230	Missense	distal	-4	no	17.559	17.723	EPSD	COSMIC;CCLE	8.808	Up-regulation
CMGC_CDK_CDK5_CDK5_ST	Q9UQL6	HDAC5	Q00535	CDK5	T234	P236S	236	Missense	proximal	2	no	17.559	17.541	EPSD	COSMIC	8.808	Down-regulation
CMGC_CDK_CDK5_CDK5_ST	Q9UQL6	HDAC5	Q00535	CDK5	T234	G230S	230	Missense	distal	-4	no	17.559	18.400	EPSD	COSMIC	8.808	Up-regulation
CMGC_CDK_CDK5_CDK5_ST	Q9UQL6	HDAC5	Q00535	CDK5	T234	P232T	232	Missense	proximal	-2	no	17.559	17.419	EPSD	COSMIC	8.808	Down-regulation
CMGC_CDK_CDK5_CDK5_ST	Q9UQL6	HDAC5	Q00535	CDK5	S279	R284C	284	Missense	distal	5	no	17.248	16.992	PhosphoSitePlus	COSMIC	8.808	Down-regulation
CMGC_CDK_CDK5_CDK5_ST	Q9UQL6	HDAC5	Q00535	CDK5	S279	S279N	279	Missense	central	0	yes	17.248	0.000	PhosphoSitePlus	COSMIC	8.808	Loss
CMGC_CDK_CDK5_CDK5_ST	Q9UQL6	HDAC5	Q00535	CDK5	S279	R284S	284	Missense	distal	5	no	17.248	17.185	PhosphoSitePlus	COSMIC	8.808	Down-regulation
CMGC_CDK_CDK5_CDK5_ST	Q9UQL6	HDAC5	Q00535	CDK5	S469	R476H	476	Missense	distal	7	no	17.135	17.129	EPSD	COSMIC	8.808	Down-regulation
CMGC_CDK_CDK5_CDK5_ST	Q9UQL6	HDAC5	Q00535	CDK5	S469	T473M	473	Missense	distal	4	no	17.135	17.042	EPSD	COSMIC	8.808	Down-regulation
CMGC_CDK_CDK5_CDK5_ST	Q9UQL6	HDAC5	Q00535	CDK5	S469	G474C	474	Missense	distal	5	no	17.135	17.046	EPSD	COSMIC	8.808	Down-regulation
CMGC_CDK_CDK5_CDK5_ST	Q9UQL6	HDAC5	Q00535	CDK5	S469	R476C	476	Missense	distal	7	no	17.135	17.119	EPSD	COSMIC	8.808	Down-regulation
CMGC_CDK_CDK5_CDK5_ST	Q9UQL6	HDAC5	Q00535	CDK5	S469	H466N	466	Missense	distal	-3	no	17.135	17.134	EPSD	COSMIC	8.808	Down-regulation
CMGC_CDK_CDK5_CDK5_ST	Q9UQL6	HDAC5	Q00535	CDK5	S662	R658L	658	Missense	distal	-4	no	17.696	17.338	EPSD	COSMIC	8.808	Down-regulation
CMGC_CDK_CDK5_CDK5_ST	Q9UQL6	HDAC5	Q00535	CDK5	S662	R658H	658	Missense	distal	-4	no	17.696	17.476	EPSD	COSMIC	8.808	Down-regulation
CMGC_CDK_CDK5_CDK5_ST	Q9UQL6	HDAC5	Q00535	CDK5	S662	T659S	659	Missense	distal	-3	no	17.696	17.697	EPSD	COSMIC	8.808	Up-regulation
CMGC_CDK_CDK5_CDK5_ST	Q9UQL6	HDAC5	Q00535	CDK5	S671	D674E	674	Missense	distal	3	no	17.106	17.172	EPSD	COSMIC	8.808	Up-regulation
CMGC_CDK_CDK5_CDK5_ST	Q9UQL6	HDAC5	Q00535	CDK5	S671	V677I	677	Missense	distal	6	no	17.106	17.102	EPSD	COSMIC	8.808	Down-regulation
CMGC_CDK_CDK5_CDK5_ST	Q9UQL6	HDAC5	Q00535	CDK5	S755	L762I	762	Missense	distal	7	no	17.074	17.080	EPSD	COSMIC	8.808	Up-regulation
CMGC_CDK_CDK5_CDK5_ST	Q9UQL6	HDAC5	Q00535	CDK5	S1108	E1106K	1106	Missense	proximal	-2	no	17.888	18.301	EPSD	COSMIC	8.808	Up-regulation
CMGC_CDK_CDK5_CDK5_ST	Q9UQL6	HDAC5	Q00535	CDK5	S1108	A1104T	1104	Missense	distal	-4	no	17.888	18.288	EPSD	COSMIC;CCLE	8.808	Up-regulation
CMGC_CDK_CDK5_CDK5_ST	Q5S007	LRRK2	Q00535	CDK5	S912	E915K	915	Missense	distal	3	no	7.051	9.337	EPSD	COSMIC	8.808	Gain
CMGC_CDK_CDK5_CDK5_ST	Q5S007	LRRK2	Q00535	CDK5	S926	N928H	928	Missense	proximal	2	no	15.919	15.950	EPSD	COSMIC	8.808	Up-regulation
CMGC_CDK_CDK5_CDK5_ST	Q5S007	LRRK2	Q00535	CDK5	S926	L922S	922	Missense	distal	-4	no	15.919	16.738	EPSD	COSMIC	8.808	Up-regulation
CMGC_CDK_CDK5_CDK5_ST	Q5S007	LRRK2	Q00535	CDK5	S1445	V1450I	1450	Missense	distal	5	no	17.728	17.676	EPSD	COSMIC;GDSC	8.808	Down-regulation
CMGC_CDK_CDK5_CDK5_ST	Q5S007	LRRK2	Q00535	CDK5	S1445	L1449F	1449	Missense	distal	4	no	17.728	17.699	EPSD	COSMIC	8.808	Down-regulation
CMGC_CDK_CDK5_CDK5_ST	Q5S007	LRRK2	Q00535	CDK5	S1445	S1443T	1443	Missense	proximal	-2	no	17.728	17.687	EPSD	COSMIC	8.808	Down-regulation
CMGC_CDK_CDK5_CDK5_ST	Q5S007	LRRK2	Q00535	CDK5	S1457	V1450I	1450	Missense	distal	-7	no	9.176	9.161	EPSD	COSMIC;GDSC	8.808	Down-regulation
CMGC_CDK_CDK5_CDK5_ST	Q5S007	LRRK2	Q00535	CDK5	S1457	D1458G	1458	Missense	proximal	1	no	9.176	-1.535	EPSD	COSMIC	8.808	Loss
CMGC_CDK_CDK5_CDK5_ST	Q5S007	LRRK2	Q00535	CDK5	S1627	K1623N	1623	Missense	distal	-4	no	9.543	9.155	PhosphoSitePlus	COSMIC	8.808	Down-regulation
CMGC_CDK_CDK5_CDK5_ST	Q5S007	LRRK2	Q00535	CDK5	S1627	E1632D	1632	Missense	distal	5	no	9.543	9.522	PhosphoSitePlus	COSMIC	8.808	Down-regulation
CMGC_CDK_CDK5_CDK5_ST	Q5S007	LRRK2	Q00535	CDK5	S1627	R1628H	1628	Missense	proximal	1	no	9.543	-0.023	PhosphoSitePlus	COSMIC	8.808	Loss
CMGC_CDK_CDK5_CDK5_ST	Q5S007	LRRK2	Q00535	CDK5	S1647	Q1648P	1648	Missense	proximal	1	no	7.264	16.240	EPSD	COSMIC;GDSC;CCLE	8.808	Gain
CMGC_CDK_CDK5_CDK5_ST	Q5S007	LRRK2	Q00535	CDK5	S1853	A1856V	1856	Missense	distal	3	no	9.151	9.403	EPSD	COSMIC	8.808	Up-regulation
CMGC_CDK_CDK5_CDK5_ST	Q5S007	LRRK2	Q00535	CDK5	S1853	I1852V	1852	Missense	proximal	-1	no	9.151	9.152	EPSD	COSMIC	8.808	Up-regulation
CMGC_CDK_CDK5_CDK5_ST	Q5S007	LRRK2	Q00535	CDK5	S1853	S1853F	1853	Missense	central	0	yes	9.151	0.000	EPSD	COSMIC	8.808	Loss
CMGC_CDK_CDK5_CDK5_ST	Q5S007	LRRK2	Q00535	CDK5	S1853	T1849N	1849	Missense	distal	-4	no	9.151	9.140	EPSD	COSMIC	8.808	Down-regulation
CMGC_CDK_CDK5_CDK5_ST	Q5S007	LRRK2	Q00535	CDK5	S1913	L1914P	1914	Missense	proximal	1	no	5.789	17.738	EPSD	COSMIC	8.808	Gain
CMGC_CDK_CDK5_CDK5_ST	Q5S007	LRRK2	Q00535	CDK5	T2035	E2033D	2033	Missense	proximal	-2	no	16.072	16.180	EPSD	COSMIC	8.808	Up-regulation
CMGC_CDK_CDK5_CDK5_ST	Q5S007	LRRK2	Q00535	CDK5	T2035	R2039H	2039	Missense	distal	4	no	16.072	16.032	EPSD	COSMIC	8.808	Down-regulation
CMGC_CDK_CDK5_CDK5_ST	Q5S007	LRRK2	Q00535	CDK5	T2035	A2040V	2040	Missense	distal	5	no	16.072	16.169	EPSD	COSMIC	8.808	Up-regulation
CMGC_CDK_CDK5_CDK5_ST	Q5S007	LRRK2	Q00535	CDK5	T2035	G2028R	2028	Missense	distal	-7	no	16.072	16.124	EPSD	COSMIC;GDSC;CCLE	8.808	Up-regulation
CMGC_CDK_CDK5_CDK5_ST	Q5S007	LRRK2	Q00535	CDK5	T2035	K2030Q	2030	Missense	distal	-5	no	16.072	15.876	EPSD	COSMIC	8.808	Down-regulation
CMGC_CDK_CDK5_CDK5_ST	O15169	AXIN1	Q00535	CDK5	T60	T58M	58	Missense	proximal	-2	no	18.864	18.430	EPSD	COSMIC;GDSC	8.808	Down-regulation
CMGC_CDK_CDK5_CDK5_ST	O15169	AXIN1	Q00535	CDK5	T60	T60I	60	Missense	central	0	yes	18.864	0.000	EPSD	COSMIC	8.808	Loss
CMGC_CDK_CDK5_CDK5_ST	O15169	AXIN1	Q00535	CDK5	T60	P61A	61	Missense	proximal	1	no	18.864	7.837	EPSD	COSMIC	8.808	Loss
CMGC_CDK_CDK5_CDK5_ST	O15169	AXIN1	Q00535	CDK5	T60	P61Q	61	Missense	proximal	1	no	18.864	9.888	EPSD	COSMIC	8.808	Down-regulation
CMGC_CDK_CDK5_CDK5_ST	O15169	AXIN1	Q00535	CDK5	T60	S57L	57	Missense	distal	-3	no	18.864	18.808	EPSD	COSMIC	8.808	Down-regulation
CMGC_CDK_CDK5_CDK5_ST	O15169	AXIN1	Q00535	CDK5	S77	G74S	74	Missense	distal	-3	no	17.831	17.872	EPSD	COSMIC	8.808	Up-regulation
CMGC_CDK_CDK5_CDK5_ST	O15169	AXIN1	Q00535	CDK5	S77	A76V	76	Missense	proximal	-1	no	17.831	17.835	EPSD	COSMIC	8.808	Up-regulation
CMGC_CDK_CDK5_CDK5_ST	O15169	AXIN1	Q00535	CDK5	S77	A76T	76	Missense	proximal	-1	no	17.831	17.836	EPSD	COSMIC	8.808	Up-regulation
CMGC_CDK_CDK5_CDK5_ST	O15169	AXIN1	Q00535	CDK5	S77	S75N	75	Missense	proximal	-2	no	17.831	17.718	EPSD	COSMIC	8.808	Down-regulation
CMGC_CDK_CDK5_CDK5_ST	O15169	AXIN1	Q00535	CDK5	S77	E73K	73	Missense	distal	-4	no	17.831	18.334	EPSD	COSMIC	8.808	Up-regulation
CMGC_CDK_CDK5_CDK5_ST	O15169	AXIN1	Q00535	CDK5	S77	P72T	72	Missense	distal	-5	no	17.831	17.828	EPSD	COSMIC	8.808	Down-regulation
CMGC_CDK_CDK5_CDK5_ST	O15169	AXIN1	Q00535	CDK5	S77	S75G	75	Missense	proximal	-2	no	17.831	17.465	EPSD	COSMIC	8.808	Down-regulation
CMGC_CDK_CDK5_CDK5_ST	O15169	AXIN1	Q00535	CDK5	S77	P78S	78	Missense	proximal	1	no	17.831	5.930	EPSD	COSMIC	8.808	Loss
CMGC_CDK_CDK5_CDK5_ST	O15169	AXIN1	Q00535	CDK5	T79	G74S	74	Missense	distal	-5	no	16.806	16.977	EPSD	COSMIC	8.808	Up-regulation
CMGC_CDK_CDK5_CDK5_ST	O15169	AXIN1	Q00535	CDK5	T79	A76V	76	Missense	distal	-3	no	16.806	16.844	EPSD	COSMIC	8.808	Up-regulation
CMGC_CDK_CDK5_CDK5_ST	O15169	AXIN1	Q00535	CDK5	T79	A76T	76	Missense	distal	-3	no	16.806	16.851	EPSD	COSMIC	8.808	Up-regulation
CMGC_CDK_CDK5_CDK5_ST	O15169	AXIN1	Q00535	CDK5	T79	S75N	75	Missense	distal	-4	no	16.806	16.293	EPSD	COSMIC	8.808	Down-regulation
CMGC_CDK_CDK5_CDK5_ST	O15169	AXIN1	Q00535	CDK5	T79	E73K	73	Missense	distal	-6	no	16.806	16.936	EPSD	COSMIC	8.808	Up-regulation
CMGC_CDK_CDK5_CDK5_ST	O15169	AXIN1	Q00535	CDK5	T79	P72T	72	Missense	distal	-7	no	16.806	16.796	EPSD	COSMIC	8.808	Down-regulation
CMGC_CDK_CDK5_CDK5_ST	O15169	AXIN1	Q00535	CDK5	T79	S75G	75	Missense	distal	-4	no	16.806	15.965	EPSD	COSMIC	8.808	Down-regulation
CMGC_CDK_CDK5_CDK5_ST	O15169	AXIN1	Q00535	CDK5	T79	P78S	78	Missense	proximal	-1	no	16.806	16.807	EPSD	COSMIC	8.808	Up-regulation
CMGC_CDK_CDK5_CDK5_ST	O15169	AXIN1	Q00535	CDK5	S217	T213I	213	Missense	distal	-4	no	18.166	18.053	EPSD	COSMIC	8.808	Down-regulation
CMGC_CDK_CDK5_CDK5_ST	O15169	AXIN1	Q00535	CDK5	S217	P218S	218	Missense	proximal	1	no	18.166	6.265	EPSD	COSMIC	8.808	Loss
CMGC_CDK_CDK5_CDK5_ST	O15169	AXIN1	Q00535	CDK5	S217	S215L	215	Missense	proximal	-2	no	18.166	17.850	EPSD	COSMIC	8.808	Down-regulation
CMGC_CDK_CDK5_CDK5_ST	O15169	AXIN1	Q00535	CDK5	S283	S282C	282	Missense	proximal	-1	no	8.857	8.850	EPSD	COSMIC	8.808	Down-regulation
CMGC_CDK_CDK5_CDK5_ST	O15169	AXIN1	Q00535	CDK5	S283	A277G	277	Missense	distal	-6	no	8.857	8.876	EPSD	COSMIC	8.808	Up-regulation
CMGC_CDK_CDK5_CDK5_ST	O15169	AXIN1	Q00535	CDK5	S283	R285W	285	Missense	proximal	2	no	8.857	8.665	EPSD	COSMIC;CCLE	8.808	Loss
CMGC_CDK_CDK5_CDK5_ST	O15169	AXIN1	Q00535	CDK5	S283	R290K	290	Missense	distal	7	no	8.857	8.862	EPSD	COSMIC	8.808	Up-regulation
CMGC_CDK_CDK5_CDK5_ST	O15169	AXIN1	Q00535	CDK5	S283	A276V	276	Missense	distal	-7	no	8.857	8.893	EPSD	COSMIC	8.808	Up-regulation
CMGC_CDK_CDK5_CDK5_ST	O15169	AXIN1	Q00535	CDK5	S283	A276G	276	Missense	distal	-7	no	8.857	8.859	EPSD	COSMIC	8.808	Up-regulation
CMGC_CDK_CDK5_CDK5_ST	O15169	AXIN1	Q00535	CDK5	T481	G488V	488	Missense	distal	7	no	19.083	19.089	PhosphoSitePlus	COSMIC	8.808	Up-regulation
CMGC_CDK_CDK5_CDK5_ST	O15169	AXIN1	Q00535	CDK5	T481	P487L	487	Missense	distal	6	no	19.083	19.069	PhosphoSitePlus	COSMIC	8.808	Down-regulation
CMGC_CDK_CDK5_CDK5_ST	O15169	AXIN1	Q00535	CDK5	T481	P482H	482	Missense	proximal	1	no	19.083	0.571	PhosphoSitePlus	COSMIC	8.808	Loss
CMGC_CDK_CDK5_CDK5_ST	O15169	AXIN1	Q00535	CDK5	T481	Q476K	476	Missense	distal	-5	no	19.083	19.278	PhosphoSitePlus	COSMIC	8.808	Up-regulation
CMGC_CDK_CDK5_CDK5_ST	O15169	AXIN1	Q00535	CDK5	S486	R492H	492	Missense	distal	6	no	18.917	18.906	EPSD	COSMIC	8.808	Down-regulation
CMGC_CDK_CDK5_CDK5_ST	O15169	AXIN1	Q00535	CDK5	S486	G488V	488	Missense	proximal	2	no	18.917	18.977	EPSD	COSMIC	8.808	Up-regulation
CMGC_CDK_CDK5_CDK5_ST	O15169	AXIN1	Q00535	CDK5	S486	H491R	491	Missense	distal	5	no	18.917	19.021	EPSD	COSMIC	8.808	Up-regulation
CMGC_CDK_CDK5_CDK5_ST	O15169	AXIN1	Q00535	CDK5	S486	R492L	492	Missense	distal	6	no	18.917	18.895	EPSD	COSMIC	8.808	Down-regulation
CMGC_CDK_CDK5_CDK5_ST	O15169	AXIN1	Q00535	CDK5	S486	P487L	487	Missense	proximal	1	no	18.917	6.968	EPSD	COSMIC	8.808	Loss
CMGC_CDK_CDK5_CDK5_ST	O15169	AXIN1	Q00535	CDK5	S486	P482H	482	Missense	distal	-4	no	18.917	18.582	EPSD	COSMIC	8.808	Down-regulation
CMGC_CDK_CDK5_CDK5_ST	O15169	AXIN1	Q00535	CDK5	S486	H491Y	491	Missense	distal	5	no	18.917	18.780	EPSD	COSMIC	8.808	Down-regulation
CMGC_CDK_CDK5_CDK5_ST	O15169	AXIN1	Q00535	CDK5	S493	P494R	494	Missense	proximal	1	no	17.697	8.750	EPSD	COSMIC	8.808	Loss
CMGC_CDK_CDK5_CDK5_ST	O15169	AXIN1	Q00535	CDK5	S493	R492H	492	Missense	proximal	-1	no	17.697	17.695	EPSD	COSMIC	8.808	Down-regulation
CMGC_CDK_CDK5_CDK5_ST	O15169	AXIN1	Q00535	CDK5	S493	G488V	488	Missense	distal	-5	no	17.697	17.812	EPSD	COSMIC	8.808	Up-regulation
CMGC_CDK_CDK5_CDK5_ST	O15169	AXIN1	Q00535	CDK5	S493	H491R	491	Missense	proximal	-2	no	17.697	17.959	EPSD	COSMIC	8.808	Up-regulation
CMGC_CDK_CDK5_CDK5_ST	O15169	AXIN1	Q00535	CDK5	S493	R492L	492	Missense	proximal	-1	no	17.697	17.692	EPSD	COSMIC	8.808	Down-regulation
CMGC_CDK_CDK5_CDK5_ST	O15169	AXIN1	Q00535	CDK5	S493	P487L	487	Missense	distal	-6	no	17.697	17.614	EPSD	COSMIC	8.808	Down-regulation
CMGC_CDK_CDK5_CDK5_ST	O15169	AXIN1	Q00535	CDK5	S493	H491Y	491	Missense	proximal	-2	no	17.697	17.485	EPSD	COSMIC	8.808	Down-regulation
CMGC_CDK_CDK5_CDK5_ST	O15169	AXIN1	Q00535	CDK5	S542	H536Y	536	Missense	distal	-6	no	8.891	8.816	EPSD	COSMIC	8.808	Down-regulation
CMGC_CDK_CDK5_CDK5_ST	O15169	AXIN1	Q00535	CDK5	S542	H540R	540	Missense	proximal	-2	no	8.891	9.152	EPSD	COSMIC	8.808	Up-regulation
CMGC_CDK_CDK5_CDK5_ST	O15169	AXIN1	Q00535	CDK5	S542	S542N	542	Missense	central	0	yes	8.891	0.000	EPSD	COSMIC	8.808	Loss
CMGC_CDK_CDK5_CDK5_ST	O15169	AXIN1	Q00535	CDK5	S542	V535I	535	Missense	distal	-7	no	8.891	8.875	EPSD	COSMIC;GDSC	8.808	Down-regulation
CMGC_CDK_CDK5_CDK5_ST	O15169	AXIN1	Q00535	CDK5	S614	A615P	615	Missense	proximal	1	no	7.600	18.626	EPSD	COSMIC	8.808	Gain
CMGC_CDK_CDK5_CDK5_ST	O15169	AXIN1	Q00535	CDK5	S644	T649P	649	Missense	distal	5	no	9.494	9.482	EPSD	COSMIC	8.808	Down-regulation
CMGC_CDK_CDK5_CDK5_ST	O15169	AXIN1	Q00535	CDK5	S644	R648S	648	Missense	distal	4	no	9.494	9.477	EPSD	COSMIC	8.808	Down-regulation
CMGC_CDK_CDK5_CDK5_ST	O15169	AXIN1	Q00535	CDK5	S644	E640K	640	Missense	distal	-4	no	9.494	9.997	EPSD	COSMIC	8.808	Up-regulation
CMGC_CDK_CDK5_CDK5_ST	O15169	AXIN1	Q00535	CDK5	S644	E642K	642	Missense	proximal	-2	no	9.494	9.907	EPSD	COSMIC	8.808	Up-regulation
CMGC_CDK_CDK5_CDK5_ST	O15169	AXIN1	Q00535	CDK5	S644	R645M	645	Missense	proximal	1	no	9.494	-1.822	EPSD	COSMIC	8.808	Loss
CMGC_CDK_CDK5_CDK5_ST	O15169	AXIN1	Q00535	CDK5	S644	S644N	644	Missense	central	0	yes	9.494	0.000	EPSD	COSMIC	8.808	Loss
CMGC_CDK_CDK5_CDK5_ST	O15169	AXIN1	Q00535	CDK5	S644	E638K	638	Missense	distal	-6	no	9.494	9.624	EPSD	COSMIC	8.808	Up-regulation
CMGC_CDK_CDK5_CDK5_ST	O15169	AXIN1	Q00535	CDK5	S644	R648K	648	Missense	distal	4	no	9.494	9.541	EPSD	COSMIC	8.808	Up-regulation
CMGC_CDK_CDK5_CDK5_ST	O15169	AXIN1	Q00535	CDK5	S644	R647H	647	Missense	distal	3	no	9.494	8.475	EPSD	COSMIC	8.808	Loss
CMGC_CDK_CDK5_CDK5_ST	P49768	PSEN1	Q00535	CDK5	S51	H46P	46	Missense	distal	-5	no	9.934	10.004	EPSD	COSMIC	8.808	Up-regulation
CMGC_CDK_CDK5_CDK5_ST	P49768	PSEN1	Q00535	CDK5	S319	E318G	318	Missense	proximal	-1	no	9.168	9.167	EPSD	COSMIC	8.808	Down-regulation
CMGC_CDK_CDK5_CDK5_ST	P49768	PSEN1	Q00535	CDK5	S319	Q325R	325	Missense	distal	6	no	9.168	9.179	EPSD	COSMIC	8.808	Up-regulation
CMGC_CDK_CDK5_CDK5_ST	P49768	PSEN1	Q00535	CDK5	S319	Y315C	315	Missense	distal	-4	no	9.168	9.125	EPSD	COSMIC	8.808	Down-regulation
CMGC_CDK_CDK5_CDK5_ST	P49768	PSEN1	Q00535	CDK5	S319	E323Q	323	Missense	distal	4	no	9.168	9.191	EPSD	COSMIC	8.808	Up-regulation
CMGC_CDK_CDK5_CDK5_ST	P49768	PSEN1	Q00535	CDK5	S324	E318G	318	Missense	distal	-6	no	9.836	9.828	EPSD	COSMIC	8.808	Down-regulation
CMGC_CDK_CDK5_CDK5_ST	P49768	PSEN1	Q00535	CDK5	S324	Q325R	325	Missense	proximal	1	no	9.836	9.865	EPSD	COSMIC	8.808	Up-regulation
CMGC_CDK_CDK5_CDK5_ST	P49768	PSEN1	Q00535	CDK5	S324	E323Q	323	Missense	proximal	-1	no	9.836	9.838	EPSD	COSMIC	8.808	Up-regulation
CMGC_CDK_CDK5_CDK5_ST	P49768	PSEN1	Q00535	CDK5	T354	R352H	352	Missense	proximal	-2	no	17.332	17.070	PhosphoSitePlus	COSMIC;CCLE	8.808	Down-regulation
CMGC_CDK_CDK5_CDK5_ST	P49768	PSEN1	Q00535	CDK5	S357	R352H	352	Missense	distal	-5	no	10.082	9.910	EPSD	COSMIC;CCLE	8.808	Down-regulation
CMGC_CDK_CDK5_CDK5_ST	P49768	PSEN1	Q00535	CDK5	S357	L364V	364	Missense	distal	7	no	10.082	10.092	EPSD	COSMIC	8.808	Up-regulation
CMGC_CDK_CDK5_CDK5_ST	P02545	LMNA	Q00535	CDK5	T10	G13A	13	Missense	distal	3	no	9.537	9.276	EPSD	COSMIC	8.808	Down-regulation
CMGC_CDK_CDK5_CDK5_ST	P02545	LMNA	Q00535	CDK5	T19	G13A	13	Missense	distal	-6	no	18.613	18.593	EPSD	COSMIC	8.808	Down-regulation
CMGC_CDK_CDK5_CDK5_ST	P02545	LMNA	Q00535	CDK5	S71	S66F	66	Missense	distal	-5	no	8.851	8.521	EPSD	COSMIC	8.808	Loss
CMGC_CDK_CDK5_CDK5_ST	P02545	LMNA	Q00535	CDK5	S71	K78E	78	Missense	distal	7	no	8.851	8.835	EPSD	COSMIC	8.808	Down-regulation
CMGC_CDK_CDK5_CDK5_ST	P02545	LMNA	Q00535	CDK5	S71	E73K	73	Missense	proximal	2	no	8.851	9.101	EPSD	COSMIC	8.808	Up-regulation
CMGC_CDK_CDK5_CDK5_ST	P02545	LMNA	Q00535	CDK5	S277	A278P	278	Missense	proximal	1	no	8.082	19.108	EPSD	COSMIC;GDSC;CCLE	8.808	Gain
CMGC_CDK_CDK5_CDK5_ST	P02545	LMNA	Q00535	CDK5	S295	R298L	298	Missense	distal	3	no	9.880	7.410	EPSD	COSMIC	8.808	Loss
CMGC_CDK_CDK5_CDK5_ST	P02545	LMNA	Q00535	CDK5	S295	R298C	298	Missense	distal	3	no	9.880	7.584	EPSD	COSMIC;GDSC;CCLE	8.808	Loss
CMGC_CDK_CDK5_CDK5_ST	P02545	LMNA	Q00535	CDK5	S295	R296C	296	Missense	proximal	1	no	9.880	-1.847	EPSD	COSMIC	8.808	Loss
CMGC_CDK_CDK5_CDK5_ST	P02545	LMNA	Q00535	CDK5	S307	Q310K	310	Missense	distal	3	no	9.375	11.497	EPSD	COSMIC	8.808	Up-regulation
CMGC_CDK_CDK5_CDK5_ST	P02545	LMNA	Q00535	CDK5	S390	E383K	383	Missense	distal	-7	no	18.452	18.515	EPSD	COSMIC;GDSC;CCLE	8.808	Up-regulation
CMGC_CDK_CDK5_CDK5_ST	P02545	LMNA	Q00535	CDK5	S390	R388L	388	Missense	proximal	-2	no	18.452	18.092	EPSD	COSMIC	8.808	Down-regulation
CMGC_CDK_CDK5_CDK5_ST	P02545	LMNA	Q00535	CDK5	S390	L389R	389	Missense	proximal	-1	no	18.452	18.457	EPSD	COSMIC	8.808	Up-regulation
CMGC_CDK_CDK5_CDK5_ST	P02545	LMNA	Q00535	CDK5	S392	R388L	388	Missense	distal	-4	no	18.400	18.042	PhosphoSitePlus	COSMIC	8.808	Down-regulation
CMGC_CDK_CDK5_CDK5_ST	P02545	LMNA	Q00535	CDK5	S392	L389R	389	Missense	distal	-3	no	18.400	18.469	PhosphoSitePlus	COSMIC	8.808	Up-regulation
CMGC_CDK_CDK5_CDK5_ST	P02545	LMNA	Q00535	CDK5	S395	R388L	388	Missense	distal	-7	no	9.159	9.103	EPSD	COSMIC	8.808	Down-regulation
CMGC_CDK_CDK5_CDK5_ST	P02545	LMNA	Q00535	CDK5	S395	L389R	389	Missense	distal	-6	no	9.159	9.288	EPSD	COSMIC	8.808	Up-regulation
CMGC_CDK_CDK5_CDK5_ST	P02545	LMNA	Q00535	CDK5	S395	R401W	401	Missense	distal	6	no	9.159	9.142	EPSD	COSMIC	8.808	Down-regulation
CMGC_CDK_CDK5_CDK5_ST	P02545	LMNA	Q00535	CDK5	S398	S403F	403	Missense	distal	5	no	10.525	10.286	EPSD	COSMIC	8.808	Down-regulation
CMGC_CDK_CDK5_CDK5_ST	P02545	LMNA	Q00535	CDK5	S398	R401W	401	Missense	distal	3	no	10.525	8.835	EPSD	COSMIC	8.808	Down-regulation
CMGC_CDK_CDK5_CDK5_ST	P02545	LMNA	Q00535	CDK5	S426	R427H	427	Missense	proximal	1	no	8.902	-0.663	EPSD	COSMIC;GDSC;CCLE	8.808	Loss
CMGC_CDK_CDK5_CDK5_ST	P02545	LMNA	Q00535	CDK5	S426	S428C	428	Missense	proximal	2	no	8.902	8.734	EPSD	COSMIC	8.808	Loss
CMGC_CDK_CDK5_CDK5_ST	P02545	LMNA	Q00535	CDK5	S426	R419H	419	Missense	distal	-7	no	8.902	8.871	EPSD	COSMIC	8.808	Down-regulation
CMGC_CDK_CDK5_CDK5_ST	P02545	LMNA	Q00535	CDK5	S426	E422G	422	Missense	distal	-4	no	8.902	8.689	EPSD	COSMIC	8.808	Loss
CMGC_CDK_CDK5_CDK5_ST	P02545	LMNA	Q00535	CDK5	S431	A434T	434	Missense	distal	3	no	8.610	9.391	EPSD	COSMIC;GDSC;CCLE	8.808	Gain
CMGC_CDK_CDK5_CDK5_ST	P02545	LMNA	Q00535	CDK5	S431	A434S	434	Missense	distal	3	no	8.610	8.835	EPSD	COSMIC	8.808	Gain
CMGC_CDK_CDK5_CDK5_ST	P02545	LMNA	Q00535	CDK5	S507	A500S	500	Missense	distal	-7	no	17.593	17.647	EPSD	COSMIC	8.808	Up-regulation
CMGC_CDK_CDK5_CDK5_ST	P02545	LMNA	Q00535	CDK5	T623	R624Q	624	Missense	proximal	1	no	8.914	8.885	EPSD	COSMIC	8.808	Down-regulation
CMGC_CDK_CDK5_CDK5_ST	P02545	LMNA	Q00535	CDK5	T623	R624C	624	Missense	proximal	1	no	8.914	-2.812	EPSD	COSMIC;CCLE	8.808	Loss
CMGC_CDK_CDK5_CDK5_ST	P02545	LMNA	Q00535	CDK5	S652	Q659L	659	Missense	distal	7	no	18.363	18.354	EPSD	COSMIC	8.808	Down-regulation
CMGC_CDK_CDK5_CDK5_ST	P02545	LMNA	Q00535	CDK5	S652	R654Q	654	Missense	proximal	2	no	18.363	18.223	EPSD	COSMIC	8.808	Down-regulation
CMGC_CDK_CDK5_CDK5_ST	P02545	LMNA	Q00535	CDK5	T655	Q659L	659	Missense	distal	4	no	9.686	9.632	EPSD	COSMIC	8.808	Down-regulation
CMGC_CDK_CDK5_CDK5_ST	P02545	LMNA	Q00535	CDK5	T655	R654Q	654	Missense	proximal	-1	no	9.686	9.684	EPSD	COSMIC	8.808	Down-regulation
CMGC_CDK_CDK5_CDK5_ST	P02545	LMNA	Q00535	CDK5	S657	I663M	663	Missense	distal	6	no	18.641	18.631	EPSD	COSMIC	8.808	Down-regulation
CMGC_CDK_CDK5_CDK5_ST	P02545	LMNA	Q00535	CDK5	S657	Q659L	659	Missense	proximal	2	no	18.641	18.534	EPSD	COSMIC	8.808	Down-regulation
CMGC_CDK_CDK5_CDK5_ST	P02545	LMNA	Q00535	CDK5	S657	R654Q	654	Missense	distal	-3	no	18.641	18.615	EPSD	COSMIC	8.808	Down-regulation
CMGC_CDK_CDK5_CDK5_ST	Q9Y490	TLN1	Q00535	CDK5	T354	E350Q	350	Missense	distal	-4	no	9.636	9.793	EPSD	COSMIC	8.808	Up-regulation
CMGC_CDK_CDK5_CDK5_ST	Q9Y490	TLN1	Q00535	CDK5	T354	L353I	353	Missense	proximal	-1	no	9.636	9.639	EPSD	COSMIC	8.808	Up-regulation
CMGC_CDK_CDK5_CDK5_ST	Q9Y490	TLN1	Q00535	CDK5	S362	P363S	363	Missense	proximal	1	no	17.595	5.694	EPSD	COSMIC	8.808	Loss
CMGC_CDK_CDK5_CDK5_ST	Q9Y490	TLN1	Q00535	CDK5	S425	S423P	423	Missense	proximal	-2	no	19.342	19.440	PhosphoSitePlus	COSMIC	8.808	Up-regulation
CMGC_CDK_CDK5_CDK5_ST	Q9Y490	TLN1	Q00535	CDK5	S729	P730L	730	Missense	proximal	1	no	16.449	4.499	EPSD	COSMIC	8.808	Loss
CMGC_CDK_CDK5_CDK5_ST	Q9Y490	TLN1	Q00535	CDK5	S940	P942L	942	Missense	proximal	2	no	9.125	8.960	EPSD	COSMIC	8.808	Down-regulation
CMGC_CDK_CDK5_CDK5_ST	Q9Y490	TLN1	Q00535	CDK5	S940	P942R	942	Missense	proximal	2	no	9.125	9.207	EPSD	COSMIC	8.808	Up-regulation
CMGC_CDK_CDK5_CDK5_ST	Q9Y490	TLN1	Q00535	CDK5	T941	P942L	942	Missense	proximal	1	no	16.845	4.896	EPSD	COSMIC	8.808	Loss
CMGC_CDK_CDK5_CDK5_ST	Q9Y490	TLN1	Q00535	CDK5	T941	P942R	942	Missense	proximal	1	no	16.845	7.898	EPSD	COSMIC	8.808	Loss
CMGC_CDK_CDK5_CDK5_ST	Q9Y490	TLN1	Q00535	CDK5	S979	A985V	985	Missense	distal	6	no	17.479	17.488	EPSD	COSMIC;GDSC	8.808	Up-regulation
CMGC_CDK_CDK5_CDK5_ST	Q9Y490	TLN1	Q00535	CDK5	S1231	S1227W	1227	Missense	distal	-4	no	9.006	8.196	EPSD	COSMIC	8.808	Loss
CMGC_CDK_CDK5_CDK5_ST	Q9Y490	TLN1	Q00535	CDK5	S1231	F1235Y	1235	Missense	distal	4	no	9.006	9.033	EPSD	COSMIC	8.808	Up-regulation
CMGC_CDK_CDK5_CDK5_ST	Q9Y490	TLN1	Q00535	CDK5	S1260	V1257L	1257	Missense	distal	-3	no	9.702	9.656	EPSD	COSMIC	8.808	Down-regulation
CMGC_CDK_CDK5_CDK5_ST	Q9Y490	TLN1	Q00535	CDK5	S1260	G1262E	1262	Missense	proximal	2	no	9.702	9.674	EPSD	COSMIC	8.808	Down-regulation
CMGC_CDK_CDK5_CDK5_ST	Q9Y490	TLN1	Q00535	CDK5	T1263	V1257L	1257	Missense	distal	-6	no	16.873	16.795	EPSD	COSMIC	8.808	Down-regulation
CMGC_CDK_CDK5_CDK5_ST	Q9Y490	TLN1	Q00535	CDK5	T1263	R1269Q	1269	Missense	distal	6	no	16.873	16.862	EPSD	COSMIC;GDSC;CCLE	8.808	Down-regulation
CMGC_CDK_CDK5_CDK5_ST	Q9Y490	TLN1	Q00535	CDK5	S1303	S1303F	1303	Missense	central	0	yes	10.387	0.000	EPSD	COSMIC	8.808	Loss
CMGC_CDK_CDK5_CDK5_ST	Q9Y490	TLN1	Q00535	CDK5	S1411	M1407I	1407	Missense	distal	-4	no	8.749	9.203	EPSD	COSMIC	8.808	Gain
CMGC_CDK_CDK5_CDK5_ST	Q9Y490	TLN1	Q00535	CDK5	T1517	S1513F	1513	Missense	distal	-4	no	9.320	8.158	EPSD	COSMIC	8.808	Loss
CMGC_CDK_CDK5_CDK5_ST	Q9Y490	TLN1	Q00535	CDK5	T1517	R1523S	1523	Missense	distal	6	no	9.320	9.312	EPSD	COSMIC	8.808	Down-regulation
CMGC_CDK_CDK5_CDK5_ST	Q9Y490	TLN1	Q00535	CDK5	S1589	R1593Q	1593	Missense	distal	4	no	18.737	18.690	EPSD	COSMIC	8.808	Down-regulation
CMGC_CDK_CDK5_CDK5_ST	Q9Y490	TLN1	Q00535	CDK5	S1637	R1638H	1638	Missense	proximal	1	no	9.394	-0.171	EPSD	COSMIC;GDSC;CCLE	8.808	Loss
CMGC_CDK_CDK5_CDK5_ST	Q9Y490	TLN1	Q00535	CDK5	S1637	S1643F	1643	Missense	distal	6	no	9.394	9.374	EPSD	COSMIC;GDSC;CCLE	8.808	Down-regulation
CMGC_CDK_CDK5_CDK5_ST	Q9Y490	TLN1	Q00535	CDK5	S1694	R1690S	1690	Missense	distal	-4	no	9.218	9.679	EPSD	COSMIC	8.808	Up-regulation
CMGC_CDK_CDK5_CDK5_ST	Q9Y490	TLN1	Q00535	CDK5	S1875	S1875L	1875	Missense	central	0	yes	8.840	0.000	EPSD	COSMIC	8.808	Loss
CMGC_CDK_CDK5_CDK5_ST	Q9Y490	TLN1	Q00535	CDK5	S1878	S1875L	1875	Missense	distal	-3	no	18.329	18.274	EPSD	COSMIC	8.808	Down-regulation
CMGC_CDK_CDK5_CDK5_ST	Q9Y490	TLN1	Q00535	CDK5	S2040	A2045S	2045	Missense	distal	5	no	10.458	10.593	EPSD	COSMIC;GDSC;CCLE	8.808	Up-regulation
CMGC_CDK_CDK5_CDK5_ST	Q9Y490	TLN1	Q00535	CDK5	S2040	A2038P	2038	Missense	proximal	-2	no	10.458	10.835	EPSD	COSMIC	8.808	Up-regulation
CMGC_CDK_CDK5_CDK5_ST	Q9Y490	TLN1	Q00535	CDK5	S2040	A2045T	2045	Missense	distal	5	no	10.458	10.592	EPSD	COSMIC	8.808	Up-regulation
CMGC_CDK_CDK5_CDK5_ST	Q9Y490	TLN1	Q00535	CDK5	S2040	A2045V	2045	Missense	distal	5	no	10.458	10.555	EPSD	COSMIC	8.808	Up-regulation
CMGC_CDK_CDK5_CDK5_ST	Q9Y490	TLN1	Q00535	CDK5	S2162	A2158V	2158	Missense	distal	-4	no	17.127	17.547	EPSD	COSMIC	8.808	Up-regulation
CMGC_CDK_CDK5_CDK5_ST	Q9Y490	TLN1	Q00535	CDK5	S2162	K2168N	2168	Missense	distal	6	no	17.127	17.113	EPSD	COSMIC	8.808	Down-regulation
CMGC_CDK_CDK5_CDK5_ST	Q9Y490	TLN1	Q00535	CDK5	T2171	P2172S	2172	Missense	proximal	1	no	16.394	4.493	EPSD	COSMIC	8.808	Loss
CMGC_CDK_CDK5_CDK5_ST	Q9Y490	TLN1	Q00535	CDK5	T2171	K2168N	2168	Missense	distal	-3	no	16.394	16.342	EPSD	COSMIC	8.808	Down-regulation
CMGC_CDK_CDK5_CDK5_ST	Q9Y490	TLN1	Q00535	CDK5	T2171	R2177Q	2177	Missense	distal	6	no	16.394	16.383	EPSD	COSMIC	8.808	Down-regulation
CMGC_CDK_CDK5_CDK5_ST	Q9Y490	TLN1	Q00535	CDK5	S2262	Q2259H	2259	Missense	distal	-3	no	16.574	16.568	EPSD	COSMIC	8.808	Down-regulation
CMGC_CDK_CDK5_CDK5_ST	O94916	NFAT5	Q00535	CDK5	S145	P146L	146	Missense	proximal	1	no	17.438	5.488	EPSD	COSMIC	8.808	Loss
CMGC_CDK_CDK5_CDK5_ST	O94916	NFAT5	Q00535	CDK5	S238	H234P	234	Missense	distal	-4	no	8.502	8.837	EPSD	COSMIC	8.808	Gain
CMGC_CDK_CDK5_CDK5_ST	O94916	NFAT5	Q00535	CDK5	S266	V263I	263	Missense	distal	-3	no	15.618	15.603	EPSD	COSMIC	8.808	Down-regulation
CMGC_CDK_CDK5_CDK5_ST	O94916	NFAT5	Q00535	CDK5	S266	S266I	266	Missense	central	0	yes	15.618	0.000	EPSD	COSMIC	8.808	Loss
CMGC_CDK_CDK5_CDK5_ST	O94916	NFAT5	Q00535	CDK5	T431	S425C	425	Missense	distal	-6	no	16.366	16.220	EPSD	COSMIC	8.808	Down-regulation
CMGC_CDK_CDK5_CDK5_ST	O94916	NFAT5	Q00535	CDK5	S561	E558K	558	Missense	distal	-3	no	19.395	19.468	EPSD	COSMIC	8.808	Up-regulation
CMGC_CDK_CDK5_CDK5_ST	O94916	NFAT5	Q00535	CDK5	S561	A563T	563	Missense	proximal	2	no	19.395	19.514	EPSD	COSMIC	8.808	Up-regulation
CMGC_CDK_CDK5_CDK5_ST	O94916	NFAT5	Q00535	CDK5	S561	K556N	556	Missense	distal	-5	no	19.395	19.189	EPSD	COSMIC	8.808	Down-regulation
CMGC_CDK_CDK5_CDK5_ST	O94916	NFAT5	Q00535	CDK5	S561	S560F	560	Missense	proximal	-1	no	19.395	19.387	EPSD	COSMIC	8.808	Down-regulation
CMGC_CDK_CDK5_CDK5_ST	O94916	NFAT5	Q00535	CDK5	S561	P565H	565	Missense	distal	4	no	19.395	19.374	EPSD	COSMIC	8.808	Down-regulation
CMGC_CDK_CDK5_CDK5_ST	O94916	NFAT5	Q00535	CDK5	T594	M593I	593	Missense	proximal	-1	no	16.869	16.873	EPSD	COSMIC	8.808	Up-regulation
CMGC_CDK_CDK5_CDK5_ST	O94916	NFAT5	Q00535	CDK5	T594	M601V	601	Missense	distal	7	no	16.869	16.881	EPSD	COSMIC	8.808	Up-regulation
CMGC_CDK_CDK5_CDK5_ST	O94916	NFAT5	Q00535	CDK5	T594	P595A	595	Missense	proximal	1	no	16.869	5.843	EPSD	COSMIC	8.808	Loss
CMGC_CDK_CDK5_CDK5_ST	O94916	NFAT5	Q00535	CDK5	T608	E605D	605	Missense	distal	-3	no	17.221	17.218	EPSD	COSMIC	8.808	Down-regulation
CMGC_CDK_CDK5_CDK5_ST	O94916	NFAT5	Q00535	CDK5	T608	A614E	614	Missense	distal	6	no	17.221	17.223	EPSD	COSMIC	8.808	Up-regulation
CMGC_CDK_CDK5_CDK5_ST	O94916	NFAT5	Q00535	CDK5	T608	V612E	612	Missense	distal	4	no	17.221	17.187	EPSD	COSMIC	8.808	Down-regulation
CMGC_CDK_CDK5_CDK5_ST	O94916	NFAT5	Q00535	CDK5	T608	K603N	603	Missense	distal	-5	no	17.221	17.014	EPSD	COSMIC	8.808	Down-regulation
CMGC_CDK_CDK5_CDK5_ST	O94916	NFAT5	Q00535	CDK5	T608	M601V	601	Missense	distal	-7	no	17.221	17.275	EPSD	COSMIC	8.808	Up-regulation
CMGC_CDK_CDK5_CDK5_ST	O94916	NFAT5	Q00535	CDK5	T631	E636Q	636	Missense	distal	5	no	9.031	9.082	EPSD	COSMIC	8.808	Up-regulation
CMGC_CDK_CDK5_CDK5_ST	O94916	NFAT5	Q00535	CDK5	T631	V628I	628	Missense	distal	-3	no	9.031	9.016	EPSD	COSMIC	8.808	Down-regulation
CMGC_CDK_CDK5_CDK5_ST	O94916	NFAT5	Q00535	CDK5	T631	S630T	630	Missense	proximal	-1	no	9.031	9.030	EPSD	COSMIC	8.808	Down-regulation
CMGC_CDK_CDK5_CDK5_ST	O94916	NFAT5	Q00535	CDK5	S649	S648T	648	Missense	proximal	-1	no	16.674	16.673	EPSD	COSMIC	8.808	Down-regulation
CMGC_CDK_CDK5_CDK5_ST	O94916	NFAT5	Q00535	CDK5	S649	S651T	651	Missense	proximal	2	no	16.674	16.699	EPSD	COSMIC	8.808	Up-regulation
CMGC_CDK_CDK5_CDK5_ST	O94916	NFAT5	Q00535	CDK5	S649	S646A	646	Missense	distal	-3	no	16.674	16.627	EPSD	COSMIC	8.808	Down-regulation
CMGC_CDK_CDK5_CDK5_ST	O94916	NFAT5	Q00535	CDK5	S649	G643R	643	Missense	distal	-6	no	16.674	16.776	EPSD	COSMIC	8.808	Up-regulation
CMGC_CDK_CDK5_CDK5_ST	O94916	NFAT5	Q00535	CDK5	S744	E748G	748	Missense	distal	4	no	16.411	16.413	EPSD	COSMIC	8.808	Up-regulation
CMGC_CDK_CDK5_CDK5_ST	O94916	NFAT5	Q00535	CDK5	S744	S738T	738	Missense	distal	-6	no	16.411	16.383	EPSD	COSMIC	8.808	Down-regulation
CMGC_CDK_CDK5_CDK5_ST	O94916	NFAT5	Q00535	CDK5	S744	E748K	748	Missense	distal	4	no	16.411	16.528	EPSD	COSMIC	8.808	Up-regulation
CMGC_CDK_CDK5_CDK5_ST	O94916	NFAT5	Q00535	CDK5	S744	A737T	737	Missense	distal	-7	no	16.411	16.451	EPSD	COSMIC	8.808	Up-regulation
CMGC_CDK_CDK5_CDK5_ST	O94916	NFAT5	Q00535	CDK5	S1247	Q1252E	1252	Missense	distal	5	no	9.010	8.959	EPSD	COSMIC	8.808	Down-regulation
CMGC_CDK_CDK5_CDK5_ST	O94916	NFAT5	Q00535	CDK5	S1247	Q1242E	1242	Missense	distal	-5	no	9.010	8.915	EPSD	COSMIC	8.808	Down-regulation
CMGC_CDK_CDK5_CDK5_ST	O94916	NFAT5	Q00535	CDK5	S1247	N1244D	1244	Missense	distal	-3	no	9.010	8.987	EPSD	COSMIC	8.808	Down-regulation
CMGC_CDK_CDK5_CDK5_ST	O94916	NFAT5	Q00535	CDK5	S1247	P1246L	1246	Missense	proximal	-1	no	9.010	9.005	EPSD	COSMIC	8.808	Down-regulation
CMGC_CDK_CDK5_CDK5_ST	O94916	NFAT5	Q00535	CDK5	S1247	P1246Q	1246	Missense	proximal	-1	no	9.010	9.009	EPSD	COSMIC	8.808	Down-regulation
CMGC_CDK_CDK5_CDK5_ST	O94916	NFAT5	Q00535	CDK5	S1247	N1244Y	1244	Missense	distal	-3	no	9.010	8.970	EPSD	COSMIC	8.808	Down-regulation
CMGC_CDK_CDK5_CDK5_ST	O94916	NFAT5	Q00535	CDK5	S1247	S1247Y	1247	Missense	central	0	yes	9.010	0.000	EPSD	COSMIC	8.808	Loss
CMGC_CDK_CDK5_CDK5_ST	O94916	NFAT5	Q00535	CDK5	S1364	Q1357E	1357	Missense	distal	-7	no	17.235	17.210	EPSD	COSMIC	8.808	Down-regulation
CMGC_CDK_CDK5_CDK5_ST	O94916	NFAT5	Q00535	CDK5	S1364	S1366R	1366	Missense	proximal	2	no	17.235	17.334	EPSD	COSMIC	8.808	Up-regulation
CMGC_CDK_CDK5_CDK5_ST	O94916	NFAT5	Q00535	CDK5	S1364	Q1359R	1359	Missense	distal	-5	no	17.235	17.396	EPSD	COSMIC	8.808	Up-regulation
CMGC_CDK_CDK5_CDK5_ST	O94916	NFAT5	Q00535	CDK5	S1364	Q1357L	1357	Missense	distal	-7	no	17.235	17.199	EPSD	COSMIC	8.808	Down-regulation
CMGC_CDK_CDK5_CDK5_ST	Q15833	STXBP2	Q00535	CDK5	S78	V84I	84	Missense	distal	6	no	16.781	16.777	EPSD	COSMIC	8.808	Down-regulation
CMGC_CDK_CDK5_CDK5_ST	Q15833	STXBP2	Q00535	CDK5	T94	G93E	93	Missense	proximal	-1	no	16.636	16.637	EPSD	COSMIC	8.808	Up-regulation
CMGC_CDK_CDK5_CDK5_ST	Q15833	STXBP2	Q00535	CDK5	T216	G222V	222	Missense	distal	6	no	15.645	15.652	EPSD	COSMIC	8.808	Up-regulation
CMGC_CDK_CDK5_CDK5_ST	Q15833	STXBP2	Q00535	CDK5	T216	F212V	212	Missense	distal	-4	no	15.645	16.324	EPSD	COSMIC	8.808	Up-regulation
CMGC_CDK_CDK5_CDK5_ST	Q15833	STXBP2	Q00535	CDK5	S458	G453D	453	Missense	distal	-5	no	8.894	8.900	EPSD	COSMIC	8.808	Up-regulation
CMGC_CDK_CDK5_CDK5_ST	Q15833	STXBP2	Q00535	CDK5	S458	P462L	462	Missense	distal	4	no	8.894	8.813	EPSD	COSMIC	8.808	Down-regulation
CMGC_CDK_CDK5_CDK5_ST	Q15833	STXBP2	Q00535	CDK5	S458	S454L	454	Missense	distal	-4	no	8.894	8.074	EPSD	COSMIC	8.808	Loss
CMGC_CDK_CDK5_CDK5_ST	Q15833	STXBP2	Q00535	CDK5	S473	P468S	468	Missense	distal	-5	no	9.688	9.711	EPSD	COSMIC	8.808	Up-regulation
CMGC_CDK_CDK5_CDK5_ST	Q15833	STXBP2	Q00535	CDK5	S473	S473F	473	Missense	central	0	yes	9.688	0.000	EPSD	COSMIC	8.808	Loss
CMGC_CDK_CDK5_CDK5_ST	Q15833	STXBP2	Q00535	CDK5	S508	P502L	502	Missense	distal	-6	no	8.814	8.731	EPSD	COSMIC	8.808	Loss
CMGC_CDK_CDK5_CDK5_ST	Q15833	STXBP2	Q00535	CDK5	S508	T505M	505	Missense	distal	-3	no	8.814	8.751	EPSD	COSMIC	8.808	Loss
CMGC_CDK_CDK5_CDK5_ST	Q15833	STXBP2	Q00535	CDK5	S508	A503T	503	Missense	distal	-5	no	8.814	8.970	EPSD	COSMIC;GDSC;CCLE	8.808	Up-regulation
CMGC_CDK_CDK5_CDK5_ST	Q15833	STXBP2	Q00535	CDK5	S508	A503S	503	Missense	distal	-5	no	8.814	8.996	EPSD	COSMIC	8.808	Up-regulation
CMGC_CDK_CDK5_CDK5_ST	Q15833	STXBP2	Q00535	CDK5	S508	A514T	514	Missense	distal	6	no	8.814	8.826	EPSD	COSMIC	8.808	Up-regulation
CMGC_CDK_CDK5_CDK5_ST	Q15833	STXBP2	Q00535	CDK5	T554	E558K	558	Missense	distal	4	no	8.798	8.915	EPSD	COSMIC	8.808	Gain
CMGC_CDK_CDK5_CDK5_ST	Q15833	STXBP2	Q00535	CDK5	T572	L571F	571	Missense	proximal	-1	no	19.849	19.847	PhosphoSitePlus	COSMIC	8.808	Down-regulation
CMGC_CDK_CDK5_CDK5_ST	Q15833	STXBP2	Q00535	CDK5	T572	P573L	573	Missense	proximal	1	no	19.849	7.899	PhosphoSitePlus	COSMIC	8.808	Loss
CMGC_CDK_CDK5_CDK5_ST	P08670	VIM	Q00535	CDK5	S9	R4K	4	Missense	distal	-5	no	8.979	9.014	EPSD	COSMIC	8.808	Up-regulation
CMGC_CDK_CDK5_CDK5_ST	P08670	VIM	Q00535	CDK5	S22	P18L	18	Missense	distal	-4	no	9.998	9.525	EPSD	COSMIC	8.808	Down-regulation
CMGC_CDK_CDK5_CDK5_ST	P08670	VIM	Q00535	CDK5	S22	S27R	27	Missense	distal	5	no	9.998	10.061	EPSD	COSMIC	8.808	Up-regulation
CMGC_CDK_CDK5_CDK5_ST	P08670	VIM	Q00535	CDK5	S26	S27R	27	Missense	proximal	1	no	6.471	9.425	EPSD	COSMIC	8.808	Gain
CMGC_CDK_CDK5_CDK5_ST	P08670	VIM	Q00535	CDK5	T33	S34P	34	Missense	proximal	1	no	7.596	19.497	EPSD	COSMIC	8.808	Gain
CMGC_CDK_CDK5_CDK5_ST	P08670	VIM	Q00535	CDK5	S56	G59N	59	Missense	distal	3	no	16.965	16.733	PhosphoSitePlus	COSMIC	8.808	Down-regulation
CMGC_CDK_CDK5_CDK5_ST	P08670	VIM	Q00535	CDK5	S56	S55A	55	Missense	proximal	-1	no	16.965	16.959	PhosphoSitePlus	COSMIC	8.808	Down-regulation
CMGC_CDK_CDK5_CDK5_ST	P08670	VIM	Q00535	CDK5	S56	G59V	59	Missense	distal	3	no	16.965	16.956	PhosphoSitePlus	COSMIC	8.808	Down-regulation
CMGC_CDK_CDK5_CDK5_ST	P08670	VIM	Q00535	CDK5	S56	S51N	51	Missense	distal	-5	no	16.965	16.873	PhosphoSitePlus	COSMIC	8.808	Down-regulation
CMGC_CDK_CDK5_CDK5_ST	P08670	VIM	Q00535	CDK5	S56	S56Y	56	Missense	central	0	yes	16.965	0.000	PhosphoSitePlus	COSMIC	8.808	Loss
CMGC_CDK_CDK5_CDK5_ST	P08670	VIM	Q00535	CDK5	T101	E103K	103	Missense	proximal	2	no	9.368	9.618	EPSD	COSMIC	8.808	Up-regulation
CMGC_CDK_CDK5_CDK5_ST	P08670	VIM	Q00535	CDK5	T449	E448K	448	Missense	proximal	-1	no	9.448	9.454	EPSD	COSMIC	8.808	Up-regulation
CMGC_CDK_CDK5_CDK5_ST	P08670	VIM	Q00535	CDK5	T449	T446R	446	Missense	distal	-3	no	9.448	9.465	EPSD	COSMIC	8.808	Up-regulation
CMGC_CDK_CDK5_CDK5_ST	P08670	VIM	Q00535	CDK5	T449	Q453E	453	Missense	distal	4	no	9.448	9.425	EPSD	COSMIC;GDSC;CCLE	8.808	Down-regulation
CMGC_CDK_CDK5_CDK5_ST	P08670	VIM	Q00535	CDK5	T449	I455V	455	Missense	distal	6	no	9.448	9.452	EPSD	COSMIC	8.808	Up-regulation
CMGC_CDK_CDK5_CDK5_ST	P08670	VIM	Q00535	CDK5	T449	V447A	447	Missense	proximal	-2	no	9.448	9.252	EPSD	COSMIC	8.808	Down-regulation
CMGC_CDK_CDK5_CDK5_ST	P08670	VIM	Q00535	CDK5	S459	Q453E	453	Missense	distal	-6	no	9.622	9.586	EPSD	COSMIC;GDSC;CCLE	8.808	Down-regulation
CMGC_CDK_CDK5_CDK5_ST	P08670	VIM	Q00535	CDK5	S459	I455V	455	Missense	distal	-4	no	9.622	9.755	EPSD	COSMIC	8.808	Up-regulation
CAMK_CAMK1_PNCK_ST	P08238	HSP90AB1	Q6P2M8	PNCK	T89	R82H	82	Missense	distal	-7	no	7.022	7.051	PhosphoSitePlus	COSMIC	1.882	Up-regulation
CAMK_CAMK1_PNCK_ST	P08238	HSP90AB1	Q6P2M8	PNCK	T94	N101Y	101	Missense	distal	7	no	2.016	1.635	EPSD	COSMIC	1.882	Loss
CAMK_CAMK1_PNCK_ST	P08238	HSP90AB1	Q6P2M8	PNCK	S124	S124P	124	Missense	central	0	yes	2.320	0.000	EPSD	COSMIC;GDSC;CCLE	1.882	Loss
CAMK_CAMK1_PNCK_ST	P08238	HSP90AB1	Q6P2M8	PNCK	S124	M125I	125	Missense	proximal	1	no	2.320	2.461	EPSD	COSMIC	1.882	Up-regulation
CAMK_CAMK1_PNCK_ST	P08238	HSP90AB1	Q6P2M8	PNCK	S255	E258D	258	Missense	distal	3	no	2.222	2.784	EPSD	COSMIC	1.882	Up-regulation
CAMK_CAMK1_PNCK_ST	P08238	HSP90AB1	Q6P2M8	PNCK	S255	E258G	258	Missense	distal	3	no	2.222	2.399	EPSD	COSMIC	1.882	Up-regulation
CAMK_CAMK1_PNCK_ST	P08238	HSP90AB1	Q6P2M8	PNCK	S261	E258D	258	Missense	distal	-3	no	2.394	3.017	EPSD	COSMIC	1.882	Up-regulation
CAMK_CAMK1_PNCK_ST	P08238	HSP90AB1	Q6P2M8	PNCK	S261	E258G	258	Missense	distal	-3	no	2.394	2.815	EPSD	COSMIC	1.882	Up-regulation
CAMK_CAMK1_PNCK_ST	P08238	HSP90AB1	Q6P2M8	PNCK	S365	D367G	367	Missense	proximal	2	no	1.942	2.102	EPSD	COSMIC	1.882	Up-regulation
CAMK_CAMK1_PNCK_ST	P08238	HSP90AB1	Q6P2M8	PNCK	S365	C366Y	366	Missense	proximal	1	no	1.942	1.979	EPSD	COSMIC;GDSC;CCLE	1.882	Up-regulation
CAMK_CAMK1_PNCK_ST	P08238	HSP90AB1	Q6P2M8	PNCK	S365	M363R	363	Missense	proximal	-2	no	1.942	1.986	EPSD	COSMIC	1.882	Up-regulation
CAMK_CAMK1_PNCK_ST	P08238	HSP90AB1	Q6P2M8	PNCK	S365	R358C	358	Missense	distal	-7	no	1.942	1.981	EPSD	COSMIC	1.882	Up-regulation
CAMK_CAMK1_PNCK_ST	P08238	HSP90AB1	Q6P2M8	PNCK	S383	R378H	378	Missense	distal	-5	no	6.825	6.719	EPSD	COSMIC	1.882	Down-regulation
CAMK_CAMK1_PNCK_ST	P08238	HSP90AB1	Q6P2M8	PNCK	S383	S383C	383	Missense	central	0	yes	6.825	0.000	EPSD	COSMIC	1.882	Loss
CAMK_CAMK1_PNCK_ST	P08238	HSP90AB1	Q6P2M8	PNCK	S398	Q396K	396	Missense	proximal	-2	no	2.677	2.749	EPSD	COSMIC	1.882	Up-regulation
CAMK_CAMK1_PNCK_ST	P08238	HSP90AB1	Q6P2M8	PNCK	S434	G440E	440	Missense	distal	6	no	1.911	1.850	EPSD	COSMIC	1.882	Loss
CAMK_CAMK1_PNCK_ST	P08238	HSP90AB1	Q6P2M8	PNCK	S594	S587L	587	Missense	distal	-7	no	1.858	1.917	EPSD	COSMIC;GDSC;CCLE	1.882	Gain
CAMK_CAMK1_PNCK_ST	P08238	HSP90AB1	Q6P2M8	PNCK	S594	V592L	592	Missense	proximal	-2	no	1.858	1.917	EPSD	COSMIC	1.882	Gain
CAMK_CAMK1_PNCK_ST	P08238	HSP90AB1	Q6P2M8	PNCK	T616	Q609H	609	Missense	distal	-7	no	5.610	5.571	EPSD	COSMIC	1.882	Down-regulation
CAMK_CAMK1_PNCK_ST	P08238	HSP90AB1	Q6P2M8	PNCK	T616	A622T	622	Missense	distal	6	no	5.610	5.368	EPSD	COSMIC	1.882	Down-regulation
CAMK_CAMK1_PNCK_ST	P07900	HSP90AA1	Q6P2M8	PNCK	S63	K58T	58	Missense	distal	-5	no	2.429	2.295	EPSD	COSMIC	1.882	Down-regulation
CAMK_CAMK1_PNCK_ST	P07900	HSP90AA1	Q6P2M8	PNCK	S72	I78F	78	Missense	distal	6	no	2.146	1.955	EPSD	COSMIC	1.882	Down-regulation
CAMK_CAMK1_PNCK_ST	P07900	HSP90AA1	Q6P2M8	PNCK	T99	D102G	102	Missense	distal	3	no	2.113	1.728	EPSD	COSMIC	1.882	Loss
CAMK_CAMK1_PNCK_ST	P07900	HSP90AA1	Q6P2M8	PNCK	S391	D393N	393	Missense	proximal	2	no	7.125	7.386	PhosphoSitePlus;EPSD	COSMIC;CCLE	1.882	Up-regulation
CAMK_CAMK1_PNCK_ST	P07900	HSP90AA1	Q6P2M8	PNCK	T498	T495R	495	Missense	distal	-3	no	1.636	1.904	EPSD	COSMIC	1.882	Gain
CAMK_CAMK1_PNCK_ST	P07900	HSP90AA1	Q6P2M8	PNCK	S589	P596S	596	Missense	distal	7	no	2.057	2.085	EPSD	COSMIC;CCLE	1.882	Up-regulation
CAMK_CAMK1_PNCK_ST	P07900	HSP90AA1	Q6P2M8	PNCK	T624	M628I	628	Missense	distal	4	no	7.043	7.124	EPSD;PhosphoSitePlus	COSMIC	1.882	Up-regulation
CAMK_CAMK1_PNCK_ST	P07900	HSP90AA1	Q6P2M8	PNCK	T624	A630T	630	Missense	distal	6	no	7.043	6.801	EPSD;PhosphoSitePlus	COSMIC	1.882	Down-regulation
CAMK_CAMK1_PNCK_ST	O43432	EIF4G3	Q6P2M8	PNCK	S273	T269A	269	Missense	distal	-4	no	3.051	2.622	EPSD	COSMIC	1.882	Down-regulation
CAMK_CAMK1_PNCK_ST	O43432	EIF4G3	Q6P2M8	PNCK	S273	P268R	268	Missense	distal	-5	no	3.051	3.093	EPSD	COSMIC	1.882	Up-regulation
CAMK_CAMK1_PNCK_ST	O43432	EIF4G3	Q6P2M8	PNCK	S305	D309H	309	Missense	distal	4	no	1.887	2.120	EPSD	COSMIC	1.882	Up-regulation
CAMK_CAMK1_PNCK_ST	O43432	EIF4G3	Q6P2M8	PNCK	S305	P312Q	312	Missense	distal	7	no	1.887	1.864	EPSD	COSMIC	1.882	Loss
CAMK_CAMK1_PNCK_ST	O43432	EIF4G3	Q6P2M8	PNCK	S305	D298H	298	Missense	distal	-7	no	1.887	1.893	EPSD	COSMIC	1.882	Up-regulation
CAMK_CAMK1_PNCK_ST	O43432	EIF4G3	Q6P2M8	PNCK	S305	I311V	311	Missense	distal	6	no	1.887	1.758	EPSD	COSMIC	1.882	Loss
CAMK_CAMK1_PNCK_ST	O43432	EIF4G3	Q6P2M8	PNCK	S305	S304L	304	Missense	proximal	-1	no	1.887	1.070	EPSD	COSMIC	1.882	Loss
CAMK_CAMK1_PNCK_ST	O43432	EIF4G3	Q6P2M8	PNCK	S305	P306Q	306	Missense	proximal	1	no	1.887	1.906	EPSD	COSMIC	1.882	Up-regulation
CAMK_CAMK1_PNCK_ST	O43432	EIF4G3	Q6P2M8	PNCK	S351	N357D	357	Missense	distal	6	no	2.106	1.958	EPSD	COSMIC	1.882	Down-regulation
CAMK_CAMK1_PNCK_ST	O43432	EIF4G3	Q6P2M8	PNCK	S352	N357D	357	Missense	distal	5	no	2.762	2.512	EPSD	COSMIC	1.882	Down-regulation
CAMK_CAMK1_PNCK_ST	O43432	EIF4G3	Q6P2M8	PNCK	T518	R515Q	515	Missense	distal	-3	no	1.999	1.817	EPSD	COSMIC	1.882	Loss
CAMK_CAMK1_PNCK_ST	O43432	EIF4G3	Q6P2M8	PNCK	T518	R517Q	517	Missense	proximal	-1	no	1.999	2.389	EPSD	COSMIC	1.882	Up-regulation
CAMK_CAMK1_PNCK_ST	O43432	EIF4G3	Q6P2M8	PNCK	T518	P512S	512	Missense	distal	-6	no	1.999	2.027	EPSD	COSMIC	1.882	Up-regulation
CAMK_CAMK1_PNCK_ST	O43432	EIF4G3	Q6P2M8	PNCK	S543	M548L	548	Missense	distal	5	no	3.262	3.680	EPSD	COSMIC;GDSC	1.882	Up-regulation
CAMK_CAMK1_PNCK_ST	O43432	EIF4G3	Q6P2M8	PNCK	S543	L541I	541	Missense	proximal	-2	no	3.262	3.093	EPSD	COSMIC	1.882	Down-regulation
CAMK_CAMK1_PNCK_ST	O43432	EIF4G3	Q6P2M8	PNCK	S543	S549R	549	Missense	distal	6	no	3.262	3.300	EPSD	COSMIC	1.882	Up-regulation
CAMK_CAMK1_PNCK_ST	O43432	EIF4G3	Q6P2M8	PNCK	S1080	G1081D	1081	Missense	proximal	1	no	2.333	2.137	EPSD	COSMIC	1.882	Down-regulation
CAMK_CAMK1_PNCK_ST	O43432	EIF4G3	Q6P2M8	PNCK	S1156	R1153W	1153	Missense	distal	-3	no	7.091	7.248	PhosphoSitePlus	COSMIC	1.882	Up-regulation
CAMK_CAMK1_PNCK_ST	O43432	EIF4G3	Q6P2M8	PNCK	S1156	D1162Y	1162	Missense	distal	6	no	7.091	7.144	PhosphoSitePlus	COSMIC	1.882	Up-regulation
CAMK_CAMK1_PNCK_ST	O43432	EIF4G3	Q6P2M8	PNCK	S1156	R1153S	1153	Missense	distal	-3	no	7.091	7.061	PhosphoSitePlus	COSMIC	1.882	Down-regulation
CAMK_CAMK1_PNCK_ST	O43432	EIF4G3	Q6P2M8	PNCK	S1156	D1162E	1162	Missense	distal	6	no	7.091	7.066	PhosphoSitePlus	COSMIC	1.882	Down-regulation
CAMK_CAMK1_PNCK_ST	O43432	EIF4G3	Q6P2M8	PNCK	S1156	S1156Y	1156	Missense	central	0	yes	7.091	0.000	PhosphoSitePlus	COSMIC	1.882	Loss
CAMK_CAMK1_PNCK_ST	O43432	EIF4G3	Q6P2M8	PNCK	S1157	R1153W	1153	Missense	distal	-4	no	2.078	1.917	EPSD	COSMIC	1.882	Down-regulation
CAMK_CAMK1_PNCK_ST	O43432	EIF4G3	Q6P2M8	PNCK	S1157	D1162Y	1162	Missense	distal	5	no	2.078	2.443	EPSD	COSMIC	1.882	Up-regulation
CAMK_CAMK1_PNCK_ST	O43432	EIF4G3	Q6P2M8	PNCK	S1157	R1153S	1153	Missense	distal	-4	no	2.078	1.930	EPSD	COSMIC	1.882	Down-regulation
CAMK_CAMK1_PNCK_ST	O43432	EIF4G3	Q6P2M8	PNCK	S1157	D1162E	1162	Missense	distal	5	no	2.078	2.390	EPSD	COSMIC	1.882	Up-regulation
CAMK_CAMK1_PNCK_ST	O43432	EIF4G3	Q6P2M8	PNCK	S1157	Q1164E	1164	Missense	distal	7	no	2.078	2.469	EPSD	COSMIC	1.882	Up-regulation
CAMK_CAMK1_PNCK_ST	O43432	EIF4G3	Q6P2M8	PNCK	S1157	S1156Y	1156	Missense	proximal	-1	no	2.078	1.643	EPSD	COSMIC	1.882	Loss
CAMK_CAMK1_PNCK_ST	O43432	EIF4G3	Q6P2M8	PNCK	S1190	D1185Y	1185	Missense	distal	-5	no	1.970	2.241	EPSD	COSMIC	1.882	Up-regulation
CAMK_CAMK1_PNCK_ST	O43432	EIF4G3	Q6P2M8	PNCK	S1190	K1197I	1197	Missense	distal	7	no	1.970	1.919	EPSD	COSMIC	1.882	Down-regulation
CAMK_CAMK1_PNCK_ST	O43432	EIF4G3	Q6P2M8	PNCK	S1190	R1195Q	1195	Missense	distal	5	no	1.970	1.774	EPSD	COSMIC	1.882	Loss
CAMK_CAMK1_PNCK_ST	O43432	EIF4G3	Q6P2M8	PNCK	S1190	G1183S	1183	Missense	distal	-7	no	1.970	1.987	EPSD	COSMIC	1.882	Up-regulation
CAMK_CAMK1_PNCK_ST	O43432	EIF4G3	Q6P2M8	PNCK	S1190	D1185E	1185	Missense	distal	-5	no	1.970	2.360	EPSD	COSMIC	1.882	Up-regulation
CAMK_CAMK1_PNCK_ST	O43432	EIF4G3	Q6P2M8	PNCK	S1190	E1187G	1187	Missense	distal	-3	no	1.970	2.391	EPSD	COSMIC	1.882	Up-regulation
CAMK_CAMK1_PNCK_ST	O43432	EIF4G3	Q6P2M8	PNCK	S1190	E1192A	1192	Missense	proximal	2	no	1.970	1.899	EPSD	COSMIC	1.882	Down-regulation
CAMK_CAMK1_PNCK_ST	O43432	EIF4G3	Q6P2M8	PNCK	T1266	E1268K	1268	Missense	proximal	2	no	2.253	2.288	EPSD	COSMIC	1.882	Up-regulation
CAMK_CAMK1_PNCK_ST	O43432	EIF4G3	Q6P2M8	PNCK	T1266	S1270R	1270	Missense	distal	4	no	2.253	2.429	EPSD	COSMIC	1.882	Up-regulation
CAMK_CAMK1_PNCK_ST	O43432	EIF4G3	Q6P2M8	PNCK	S1412	A1415V	1415	Missense	distal	3	no	2.691	3.231	EPSD	COSMIC	1.882	Up-regulation
CAMK_CAMK1_PNCK_ST	O43432	EIF4G3	Q6P2M8	PNCK	S1412	S1409R	1409	Missense	distal	-3	no	2.691	2.721	EPSD	COSMIC	1.882	Up-regulation
CAMK_CAMK1_PNCK_ST	O43432	EIF4G3	Q6P2M8	PNCK	S1412	S1417Y	1417	Missense	distal	5	no	2.691	2.626	EPSD	COSMIC	1.882	Down-regulation
CAMK_PKD_PRKD2_ST	P50552	VASP	Q9BZL6	PRKD2	S239	G246V	246	Missense	distal	7	no	3.894	3.869	PhosphoSitePlus;EPSD	COSMIC	1.791	Down-regulation
CAMK_PKD_PRKD2_ST	P50552	VASP	Q9BZL6	PRKD2	S322	S325L	325	Missense	distal	3	no	3.733	3.765	EPSD;PhosphoSitePlus	COSMIC	1.791	Up-regulation
CAMK_PKD_PRKD2_ST	P50552	VASP	Q9BZL6	PRKD2	S322	K321E	321	Missense	proximal	-1	no	3.733	3.666	EPSD;PhosphoSitePlus	COSMIC	1.791	Down-regulation
CAMK_PKD_PRKD2_ST	P50552	VASP	Q9BZL6	PRKD2	S323	S325L	325	Missense	proximal	2	no	1.795	1.786	EPSD	COSMIC	1.791	Loss
CAMK_PKD_PRKD2_ST	P50552	VASP	Q9BZL6	PRKD2	S323	K321E	321	Missense	proximal	-2	no	1.795	1.788	EPSD	COSMIC	1.791	Loss
CAMK_PKD_PRKD2_ST	Q8WYL5	SSH1	Q9BZL6	PRKD2	S41	E40K	40	Missense	proximal	-1	no	1.780	1.846	EPSD	COSMIC	1.791	Gain
CAMK_PKD_PRKD2_ST	Q8WYL5	SSH1	Q9BZL6	PRKD2	S41	A48T	48	Missense	distal	7	no	1.780	1.793	EPSD	COSMIC;CCLE	1.791	Gain
CAMK_PKD_PRKD2_ST	Q8WYL5	SSH1	Q9BZL6	PRKD2	S400	V397M	397	Missense	distal	-3	no	1.957	1.984	EPSD	COSMIC	1.791	Up-regulation
CAMK_PKD_PRKD2_ST	Q8WYL5	SSH1	Q9BZL6	PRKD2	S400	G396C	396	Missense	distal	-4	no	1.957	1.956	EPSD	COSMIC	1.791	Down-regulation
CAMK_PKD_PRKD2_ST	Q8WYL5	SSH1	Q9BZL6	PRKD2	S402	V397M	397	Missense	distal	-5	no	1.829	1.653	EPSD	COSMIC	1.791	Loss
CAMK_PKD_PRKD2_ST	Q8WYL5	SSH1	Q9BZL6	PRKD2	S428	R427H	427	Missense	proximal	-1	no	2.263	2.338	EPSD	COSMIC	1.791	Up-regulation
CAMK_PKD_PRKD2_ST	Q8WYL5	SSH1	Q9BZL6	PRKD2	S428	A434V	434	Missense	distal	6	no	2.263	2.202	EPSD	COSMIC	1.791	Down-regulation
CAMK_PKD_PRKD2_ST	Q8WYL5	SSH1	Q9BZL6	PRKD2	S428	A434S	434	Missense	distal	6	no	2.263	2.357	EPSD	COSMIC	1.791	Up-regulation
CAMK_PKD_PRKD2_ST	Q8WYL5	SSH1	Q9BZL6	PRKD2	S441	M437I	437	Missense	distal	-4	no	1.910	1.908	EPSD	COSMIC	1.791	Down-regulation
CAMK_PKD_PRKD2_ST	Q8WYL5	SSH1	Q9BZL6	PRKD2	S441	A434V	434	Missense	distal	-7	no	1.910	1.834	EPSD	COSMIC	1.791	Down-regulation
CAMK_PKD_PRKD2_ST	Q8WYL5	SSH1	Q9BZL6	PRKD2	S441	A434S	434	Missense	distal	-7	no	1.910	1.938	EPSD	COSMIC	1.791	Up-regulation
CAMK_PKD_PRKD2_ST	Q8WYL5	SSH1	Q9BZL6	PRKD2	S441	R438L	438	Missense	distal	-3	no	1.910	0.541	EPSD	COSMIC	1.791	Loss
CAMK_PKD_PRKD2_ST	Q8WYL5	SSH1	Q9BZL6	PRKD2	S441	R438H	438	Missense	distal	-3	no	1.910	0.757	EPSD	COSMIC	1.791	Loss
CAMK_PKD_PRKD2_ST	Q8WYL5	SSH1	Q9BZL6	PRKD2	S441	R438C	438	Missense	distal	-3	no	1.910	1.062	EPSD	COSMIC	1.791	Loss
CAMK_PKD_PRKD2_ST	Q8WYL5	SSH1	Q9BZL6	PRKD2	T462	R459H	459	Missense	distal	-3	no	2.221	1.068	EPSD	COSMIC;GDSC	1.791	Loss
CAMK_PKD_PRKD2_ST	Q8WYL5	SSH1	Q9BZL6	PRKD2	S515	P517S	517	Missense	proximal	2	no	2.479	2.493	EPSD	COSMIC	1.791	Up-regulation
CAMK_PKD_PRKD2_ST	Q8WYL5	SSH1	Q9BZL6	PRKD2	S515	R512W	512	Missense	distal	-3	no	2.479	1.597	EPSD	COSMIC	1.791	Loss
CAMK_PKD_PRKD2_ST	Q8WYL5	SSH1	Q9BZL6	PRKD2	S583	R580Q	580	Missense	distal	-3	no	2.440	1.366	EPSD	COSMIC	1.791	Loss
CAMK_PKD_PRKD2_ST	Q8WYL5	SSH1	Q9BZL6	PRKD2	S583	R580W	580	Missense	distal	-3	no	2.440	1.557	EPSD	COSMIC	1.791	Loss
CAMK_PKD_PRKD2_ST	Q8WYL5	SSH1	Q9BZL6	PRKD2	S583	S576G	576	Missense	distal	-7	no	2.440	2.338	EPSD	COSMIC	1.791	Down-regulation
CAMK_PKD_PRKD2_ST	Q8WYL5	SSH1	Q9BZL6	PRKD2	S778	S778L	778	Missense	central	0	yes	2.239	0.000	EPSD	COSMIC	1.791	Loss
CAMK_PKD_PRKD2_ST	Q8WYL5	SSH1	Q9BZL6	PRKD2	S834	V835L	835	Missense	proximal	1	no	2.520	2.571	EPSD	COSMIC	1.791	Up-regulation
CAMK_PKD_PRKD2_ST	Q8WYL5	SSH1	Q9BZL6	PRKD2	S834	V835M	835	Missense	proximal	1	no	2.520	2.460	EPSD	COSMIC	1.791	Down-regulation
CAMK_PKD_PRKD2_ST	Q8WYL5	SSH1	Q9BZL6	PRKD2	S834	A840V	840	Missense	distal	6	no	2.520	2.459	EPSD	COSMIC	1.791	Down-regulation
CAMK_PKD_PRKD2_ST	Q8WYL5	SSH1	Q9BZL6	PRKD2	S883	A885S	885	Missense	proximal	2	no	1.790	1.793	EPSD	COSMIC	1.791	Gain
CAMK_PKD_PRKD2_ST	Q8WYL5	SSH1	Q9BZL6	PRKD2	S894	P887S	887	Missense	distal	-7	no	2.185	2.302	EPSD	COSMIC;GDSC;CCLE	1.791	Up-regulation
CAMK_PKD_PRKD2_ST	Q8WYL5	SSH1	Q9BZL6	PRKD2	S978	R975H	975	Missense	distal	-3	no	4.006	2.854	PhosphoSitePlus;EPSD	COSMIC	1.791	Down-regulation
CAMK_PKD_PRKD2_ST	Q8WYL5	SSH1	Q9BZL6	PRKD2	S978	S971F	971	Missense	distal	-7	no	4.006	3.860	PhosphoSitePlus;EPSD	COSMIC	1.791	Down-regulation
CAMK_PKD_PRKD2_ST	Q8WYL5	SSH1	Q9BZL6	PRKD2	S978	R975C	975	Missense	distal	-3	no	4.006	3.158	PhosphoSitePlus;EPSD	COSMIC;GDSC;CCLE	1.791	Down-regulation
CAMK_PKD_PRKD2_ST	Q8WYL5	SSH1	Q9BZL6	PRKD2	S984	T986A	986	Missense	proximal	2	no	1.911	1.916	EPSD	COSMIC;GDSC;CCLE	1.791	Up-regulation
CAMK_PKD_PRKD2_ST	Q8WYL5	SSH1	Q9BZL6	PRKD2	S984	E990K	990	Missense	distal	6	no	1.911	1.937	EPSD	COSMIC;GDSC;CCLE	1.791	Up-regulation
CAMK_PKD_PRKD2_ST	Q8WYL5	SSH1	Q9BZL6	PRKD2	T989	T986A	986	Missense	distal	-3	no	1.881	1.747	EPSD	COSMIC;GDSC;CCLE	1.791	Loss
CAMK_PKD_PRKD2_ST	Q8WYL5	SSH1	Q9BZL6	PRKD2	T989	E990K	990	Missense	proximal	1	no	1.881	1.921	EPSD	COSMIC;GDSC;CCLE	1.791	Up-regulation
CAMK_PKD_PRKD2_ST	Q9UQL6	HDAC5	Q9BZL6	PRKD2	S224	L221F	221	Missense	distal	-3	no	1.640	2.025	EPSD	COSMIC	1.791	Gain
CAMK_PKD_PRKD2_ST	Q9UQL6	HDAC5	Q9BZL6	PRKD2	S224	G230S	230	Missense	distal	6	no	1.640	1.872	EPSD	COSMIC	1.791	Gain
CAMK_PKD_PRKD2_ST	Q9UQL6	HDAC5	Q9BZL6	PRKD2	S259	R255C	255	Missense	distal	-4	no	2.265	2.260	EPSD	COSMIC	1.791	Down-regulation
CAMK_PKD_PRKD2_ST	Q9UQL6	HDAC5	Q9BZL6	PRKD2	S259	R266C	266	Missense	distal	7	no	2.265	2.274	EPSD	COSMIC	1.791	Up-regulation
CAMK_PKD_PRKD2_ST	Q9UQL6	HDAC5	Q9BZL6	PRKD2	S259	R266H	266	Missense	distal	7	no	2.265	2.280	EPSD	COSMIC	1.791	Up-regulation
CAMK_PKD_PRKD2_ST	Q9UQL6	HDAC5	Q9BZL6	PRKD2	S279	R284C	284	Missense	distal	5	no	2.881	2.912	EPSD	COSMIC	1.791	Up-regulation
CAMK_PKD_PRKD2_ST	Q9UQL6	HDAC5	Q9BZL6	PRKD2	S279	S279N	279	Missense	central	0	yes	2.881	0.000	EPSD	COSMIC	1.791	Loss
CAMK_PKD_PRKD2_ST	Q9UQL6	HDAC5	Q9BZL6	PRKD2	S279	R284S	284	Missense	distal	5	no	2.881	2.932	EPSD	COSMIC	1.791	Up-regulation
CAMK_PKD_PRKD2_ST	Q9UQL6	HDAC5	Q9BZL6	PRKD2	S291	R284C	284	Missense	distal	-7	no	1.797	1.778	EPSD	COSMIC	1.791	Loss
CAMK_PKD_PRKD2_ST	Q9UQL6	HDAC5	Q9BZL6	PRKD2	S291	G287E	287	Missense	distal	-4	no	1.797	1.792	EPSD	COSMIC	1.791	Down-regulation
CAMK_PKD_PRKD2_ST	Q9UQL6	HDAC5	Q9BZL6	PRKD2	S291	T292I	292	Missense	proximal	1	no	1.797	1.852	EPSD	COSMIC	1.791	Up-regulation
CAMK_PKD_PRKD2_ST	Q9UQL6	HDAC5	Q9BZL6	PRKD2	S291	R284S	284	Missense	distal	-7	no	1.797	1.881	EPSD	COSMIC	1.791	Up-regulation
CAMK_PKD_PRKD2_ST	Q9UQL6	HDAC5	Q9BZL6	PRKD2	S458	R455Q	455	Missense	distal	-3	no	1.989	0.915	EPSD	COSMIC	1.791	Loss
CAMK_PKD_PRKD2_ST	Q9UQL6	HDAC5	Q9BZL6	PRKD2	S458	R455W	455	Missense	distal	-3	no	1.989	1.106	EPSD	COSMIC	1.791	Loss
CAMK_PKD_PRKD2_ST	Q9UQL6	HDAC5	Q9BZL6	PRKD2	S458	L460I	460	Missense	proximal	2	no	1.989	1.995	EPSD	COSMIC	1.791	Up-regulation
CAMK_PKD_PRKD2_ST	Q9UQL6	HDAC5	Q9BZL6	PRKD2	S498	R491W	491	Missense	distal	-7	no	3.704	3.679	PhosphoSitePlus	COSMIC	1.791	Down-regulation
CAMK_PKD_PRKD2_ST	Q9UQL6	HDAC5	Q9BZL6	PRKD2	T546	E550D	550	Missense	distal	4	no	2.278	2.388	EPSD	COSMIC	1.791	Up-regulation
CAMK_PKD_PRKD2_ST	Q9UQL6	HDAC5	Q9BZL6	PRKD2	T546	E553K	553	Missense	distal	7	no	2.278	2.272	EPSD	COSMIC	1.791	Down-regulation
CAMK_PKD_PRKD2_ST	Q9UQL6	HDAC5	Q9BZL6	PRKD2	S661	R658L	658	Missense	distal	-3	no	2.542	1.173	EPSD	COSMIC	1.791	Loss
CAMK_PKD_PRKD2_ST	Q9UQL6	HDAC5	Q9BZL6	PRKD2	S661	R658H	658	Missense	distal	-3	no	2.542	1.389	EPSD	COSMIC	1.791	Loss
CAMK_PKD_PRKD2_ST	Q9UQL6	HDAC5	Q9BZL6	PRKD2	S661	T659S	659	Missense	proximal	-2	no	2.542	2.566	EPSD	COSMIC	1.791	Up-regulation
CAMK_PKD_PRKD2_ST	Q9UQL6	HDAC5	Q9BZL6	PRKD2	S713	R717H	717	Missense	distal	4	no	1.970	1.930	EPSD	COSMIC	1.791	Down-regulation
CAMK_PKD_PRKD2_ST	Q9UQL6	HDAC5	Q9BZL6	PRKD2	S713	R710Q	710	Missense	distal	-3	no	1.970	0.896	EPSD	COSMIC	1.791	Loss
CAMK_PKD_PRKD2_ST	Q9UQL6	HDAC5	Q9BZL6	PRKD2	S713	Q719H	719	Missense	distal	6	no	1.970	1.935	EPSD	COSMIC	1.791	Down-regulation
CAMK_PKD_PRKD2_ST	Q9UQL6	HDAC5	Q9BZL6	PRKD2	S713	S713G	713	Missense	central	0	yes	1.970	0.000	EPSD	COSMIC	1.791	Loss
CAMK_PKD_PRKD2_ST	Q9UQL6	HDAC5	Q9BZL6	PRKD2	S1108	E1106K	1106	Missense	proximal	-2	no	2.046	2.052	EPSD	COSMIC	1.791	Up-regulation
CAMK_PKD_PRKD2_ST	Q9UQL6	HDAC5	Q9BZL6	PRKD2	S1108	A1104T	1104	Missense	distal	-4	no	2.046	2.051	EPSD	COSMIC;CCLE	1.791	Up-regulation
CAMK_PKD_PRKD2_ST	Q13563	PKD2	Q9BZL6	PRKD2	S80	C82F	82	Missense	proximal	2	no	2.104	2.092	EPSD	COSMIC	1.791	Down-regulation
CAMK_PKD_PRKD2_ST	Q13563	PKD2	Q9BZL6	PRKD2	S122	R119H	119	Missense	distal	-3	no	1.875	0.722	EPSD	COSMIC	1.791	Loss
CAMK_PKD_PRKD2_ST	Q13563	PKD2	Q9BZL6	PRKD2	S122	S129W	129	Missense	distal	7	no	1.875	1.922	EPSD	COSMIC	1.791	Up-regulation
CAMK_PKD_PRKD2_ST	Q13563	PKD2	Q9BZL6	PRKD2	S801	M800L	800	Missense	proximal	-1	no	3.671	3.749	PhosphoSitePlus	COSMIC	1.791	Up-regulation
CAMK_PKD_PRKD2_ST	Q13563	PKD2	Q9BZL6	PRKD2	S801	P806H	806	Missense	distal	5	no	3.671	3.658	PhosphoSitePlus	COSMIC	1.791	Down-regulation
CAMK_PKD_PRKD2_ST	Q13563	PKD2	Q9BZL6	PRKD2	S829	S829C	829	Missense	central	0	yes	2.515	0.000	EPSD	COSMIC	1.791	Loss
CAMK_PKD_PRKD2_ST	Q13563	PKD2	Q9BZL6	PRKD2	S829	S835F	835	Missense	distal	6	no	2.515	2.296	EPSD	COSMIC	1.791	Down-regulation
CAMK_PKD_PRKD2_ST	Q13563	PKD2	Q9BZL6	PRKD2	S855	S852K	852	Missense	distal	-3	no	1.707	2.057	EPSD	COSMIC	1.791	Gain
CAMK_PKD_PRKD2_ST	Q7KZI7	MARK2	Q9BZL6	PRKD2	S274	N279Y	279	Missense	distal	5	no	1.792	1.787	EPSD	COSMIC	1.791	Loss
CAMK_PKD_PRKD2_ST	Q7KZI7	MARK2	Q9BZL6	PRKD2	S274	T275M	275	Missense	proximal	1	no	1.792	1.759	EPSD	COSMIC	1.791	Loss
CAMK_PKD_PRKD2_ST	Q7KZI7	MARK2	Q9BZL6	PRKD2	S274	Y267H	267	Missense	distal	-7	no	1.792	1.803	EPSD	COSMIC	1.791	Up-regulation
CAMK_PKD_PRKD2_ST	Q7KZI7	MARK2	Q9BZL6	PRKD2	S366	T372I	372	Missense	distal	6	no	2.095	2.062	EPSD	COSMIC	1.791	Down-regulation
CAMK_PKD_PRKD2_ST	Q7KZI7	MARK2	Q9BZL6	PRKD2	S366	I373L	373	Missense	distal	7	no	2.095	2.130	EPSD	COSMIC	1.791	Up-regulation
CAMK_PKD_PRKD2_ST	Q7KZI7	MARK2	Q9BZL6	PRKD2	T374	T372I	372	Missense	proximal	-2	no	1.804	1.769	EPSD	COSMIC	1.791	Loss
CAMK_PKD_PRKD2_ST	Q7KZI7	MARK2	Q9BZL6	PRKD2	T374	K376T	376	Missense	proximal	2	no	1.804	1.797	EPSD	COSMIC	1.791	Down-regulation
CAMK_PKD_PRKD2_ST	Q7KZI7	MARK2	Q9BZL6	PRKD2	T374	I373L	373	Missense	proximal	-1	no	1.804	1.807	EPSD	COSMIC	1.791	Up-regulation
CAMK_PKD_PRKD2_ST	Q7KZI7	MARK2	Q9BZL6	PRKD2	S400	R407H	407	Missense	distal	7	no	3.643	3.657	PhosphoSitePlus	COSMIC	1.791	Up-regulation
CAMK_PKD_PRKD2_ST	Q7KZI7	MARK2	Q9BZL6	PRKD2	S400	R406Q	406	Missense	distal	6	no	3.643	3.642	PhosphoSitePlus	COSMIC	1.791	Down-regulation
CAMK_PKD_PRKD2_ST	Q7KZI7	MARK2	Q9BZL6	PRKD2	S409	R407H	407	Missense	proximal	-2	no	1.952	1.723	EPSD	COSMIC	1.791	Loss
CAMK_PKD_PRKD2_ST	Q7KZI7	MARK2	Q9BZL6	PRKD2	S409	R406Q	406	Missense	distal	-3	no	1.952	0.878	EPSD	COSMIC	1.791	Loss
CAMK_PKD_PRKD2_ST	Q7KZI7	MARK2	Q9BZL6	PRKD2	S448	S443F	443	Missense	distal	-5	no	2.138	2.065	EPSD	COSMIC	1.791	Down-regulation
CAMK_PKD_PRKD2_ST	Q7KZI7	MARK2	Q9BZL6	PRKD2	S448	S448N	448	Missense	central	0	yes	2.138	0.000	EPSD	COSMIC	1.791	Loss
CAMK_PKD_PRKD2_ST	Q7KZI7	MARK2	Q9BZL6	PRKD2	S448	S449N	449	Missense	proximal	1	no	2.138	1.927	EPSD	COSMIC	1.791	Down-regulation
CAMK_PKD_PRKD2_ST	Q7KZI7	MARK2	Q9BZL6	PRKD2	S456	P457L	457	Missense	proximal	1	no	1.770	2.033	EPSD	COSMIC	1.791	Gain
CAMK_PKD_PRKD2_ST	Q7KZI7	MARK2	Q9BZL6	PRKD2	S456	P457H	457	Missense	proximal	1	no	1.770	1.933	EPSD	COSMIC	1.791	Gain
CAMK_PKD_PRKD2_ST	Q7KZI7	MARK2	Q9BZL6	PRKD2	T466	P470S	470	Missense	distal	4	no	2.131	1.776	EPSD	COSMIC	1.791	Loss
CAMK_PKD_PRKD2_ST	Q7KZI7	MARK2	Q9BZL6	PRKD2	T466	K464N	464	Missense	proximal	-2	no	2.131	2.084	EPSD	COSMIC	1.791	Down-regulation
CAMK_PKD_PRKD2_ST	Q7KZI7	MARK2	Q9BZL6	PRKD2	S493	A492T	492	Missense	proximal	-1	no	2.084	2.029	EPSD	COSMIC	1.791	Down-regulation
CAMK_PKD_PRKD2_ST	Q7KZI7	MARK2	Q9BZL6	PRKD2	S498	A492T	492	Missense	distal	-6	no	2.485	2.486	EPSD	COSMIC	1.791	Up-regulation
CAMK_PKD_PRKD2_ST	Q7KZI7	MARK2	Q9BZL6	PRKD2	S511	S514F	514	Missense	distal	3	no	1.823	1.874	EPSD	COSMIC	1.791	Up-regulation
CAMK_PKD_PRKD2_ST	Q7KZI7	MARK2	Q9BZL6	PRKD2	S511	A518T	518	Missense	distal	7	no	1.823	1.836	EPSD	COSMIC	1.791	Up-regulation
CAMK_PKD_PRKD2_ST	Q7KZI7	MARK2	Q9BZL6	PRKD2	S511	G510V	510	Missense	proximal	-1	no	1.823	1.973	EPSD	COSMIC	1.791	Up-regulation
CAMK_PKD_PRKD2_ST	Q7KZI7	MARK2	Q9BZL6	PRKD2	S511	M508I	508	Missense	distal	-3	no	1.823	1.771	EPSD	COSMIC	1.791	Loss
CAMK_PKD_PRKD2_ST	Q7KZI7	MARK2	Q9BZL6	PRKD2	S537	P540L	540	Missense	distal	3	no	1.963	1.972	EPSD	COSMIC	1.791	Up-regulation
CAMK_PKD_PRKD2_ST	Q7KZI7	MARK2	Q9BZL6	PRKD2	S537	A536V	536	Missense	proximal	-1	no	1.963	1.973	EPSD	COSMIC	1.791	Up-regulation
CAMK_PKD_PRKD2_ST	Q7KZI7	MARK2	Q9BZL6	PRKD2	S537	S535F	535	Missense	proximal	-2	no	1.963	1.842	EPSD	COSMIC	1.791	Down-regulation
CAMK_PKD_PRKD2_ST	Q7KZI7	MARK2	Q9BZL6	PRKD2	T560	R564H	564	Missense	distal	4	no	2.202	2.162	EPSD	COSMIC	1.791	Down-regulation
CAMK_PKD_PRKD2_ST	Q7KZI7	MARK2	Q9BZL6	PRKD2	T560	P562S	562	Missense	proximal	2	no	2.202	2.216	EPSD	COSMIC	1.791	Up-regulation
CAMK_PKD_PRKD2_ST	Q7KZI7	MARK2	Q9BZL6	PRKD2	T560	P566L	566	Missense	distal	6	no	2.202	2.114	EPSD	COSMIC	1.791	Down-regulation
CAMK_PKD_PRKD2_ST	Q7KZI7	MARK2	Q9BZL6	PRKD2	S577	P570H	570	Missense	distal	-7	no	1.986	2.003	EPSD	COSMIC	1.791	Up-regulation
CAMK_PKD_PRKD2_ST	Q7KZI7	MARK2	Q9BZL6	PRKD2	S577	P582Q	582	Missense	distal	5	no	1.986	2.008	EPSD	COSMIC	1.791	Up-regulation
CAMK_PKD_PRKD2_ST	Q7KZI7	MARK2	Q9BZL6	PRKD2	S577	P570T	570	Missense	distal	-7	no	1.986	2.041	EPSD	COSMIC	1.791	Up-regulation
CAMK_PKD_PRKD2_ST	Q7KZI7	MARK2	Q9BZL6	PRKD2	S577	D583H	583	Missense	distal	6	no	1.986	1.990	EPSD	COSMIC	1.791	Up-regulation
CAMK_PKD_PRKD2_ST	Q7KZI7	MARK2	Q9BZL6	PRKD2	S577	G580S	580	Missense	distal	3	no	1.986	1.952	EPSD	COSMIC	1.791	Down-regulation
CAMK_PKD_PRKD2_ST	Q7KZI7	MARK2	Q9BZL6	PRKD2	S577	G580D	580	Missense	distal	3	no	1.986	1.979	EPSD	COSMIC	1.791	Down-regulation
CAMK_PKD_PRKD2_ST	Q7KZI7	MARK2	Q9BZL6	PRKD2	S592	R589H	589	Missense	distal	-3	no	2.192	1.040	EPSD	COSMIC	1.791	Loss
CAMK_PKD_PRKD2_ST	Q7KZI7	MARK2	Q9BZL6	PRKD2	S592	P588S	588	Missense	distal	-4	no	2.192	2.171	EPSD	COSMIC	1.791	Down-regulation
CAMK_PKD_PRKD2_ST	Q7KZI7	MARK2	Q9BZL6	PRKD2	S592	R589L	589	Missense	distal	-3	no	2.192	0.824	EPSD	COSMIC	1.791	Loss
CAMK_PKD_PRKD2_ST	Q7KZI7	MARK2	Q9BZL6	PRKD2	S592	R589W	589	Missense	distal	-3	no	2.192	1.310	EPSD	COSMIC	1.791	Loss
CAMK_PKD_PRKD2_ST	Q7KZI7	MARK2	Q9BZL6	PRKD2	S592	P588L	588	Missense	distal	-4	no	2.192	2.191	EPSD	COSMIC	1.791	Down-regulation
CAMK_PKD_PRKD2_ST	Q7KZI7	MARK2	Q9BZL6	PRKD2	S592	R594H	594	Missense	proximal	2	no	2.192	2.203	EPSD	COSMIC	1.791	Up-regulation
CAMK_PKD_PRKD2_ST	Q7KZI7	MARK2	Q9BZL6	PRKD2	S592	R594L	594	Missense	proximal	2	no	2.192	2.207	EPSD	COSMIC	1.791	Up-regulation
CAMK_PKD_PRKD2_ST	Q7KZI7	MARK2	Q9BZL6	PRKD2	S592	R594C	594	Missense	proximal	2	no	2.192	2.205	EPSD	COSMIC	1.791	Up-regulation
CAMK_PKD_PRKD2_ST	Q7KZI7	MARK2	Q9BZL6	PRKD2	S593	P588S	588	Missense	distal	-5	no	1.620	1.892	EPSD	COSMIC	1.791	Gain
CAMK_PKD_PRKD2_ST	Q7KZI7	MARK2	Q9BZL6	PRKD2	S593	P588L	588	Missense	distal	-5	no	1.620	2.408	EPSD	COSMIC	1.791	Gain
CAMK_PKD_PRKD2_ST	Q7KZI7	MARK2	Q9BZL6	PRKD2	S593	R594H	594	Missense	proximal	1	no	1.620	1.800	EPSD	COSMIC	1.791	Gain
CAMK_PKD_PRKD2_ST	Q7KZI7	MARK2	Q9BZL6	PRKD2	S593	R594L	594	Missense	proximal	1	no	1.620	1.900	EPSD	COSMIC	1.791	Gain
CAMK_PKD_PRKD2_ST	Q7KZI7	MARK2	Q9BZL6	PRKD2	S631	R627H	627	Missense	distal	-4	no	2.233	2.228	EPSD	COSMIC	1.791	Down-regulation
CAMK_PKD_PRKD2_ST	Q7KZI7	MARK2	Q9BZL6	PRKD2	S631	R627L	627	Missense	distal	-4	no	2.233	2.227	EPSD	COSMIC	1.791	Down-regulation
CAMK_PKD_PRKD2_ST	Q7KZI7	MARK2	Q9BZL6	PRKD2	S631	R627C	627	Missense	distal	-4	no	2.233	2.229	EPSD	COSMIC	1.791	Down-regulation
CAMK_PKD_PRKD2_ST	Q7KZI7	MARK2	Q9BZL6	PRKD2	S631	K637T	637	Missense	distal	6	no	2.233	2.208	EPSD	COSMIC	1.791	Down-regulation
CAMK_PKD_PRKD2_ST	Q7KZI7	MARK2	Q9BZL6	PRKD2	S648	K641R	641	Missense	distal	-7	no	1.913	1.853	EPSD	COSMIC	1.791	Down-regulation
CAMK_PKD_PRKD2_ST	Q7KZI7	MARK2	Q9BZL6	PRKD2	S698	R691H	691	Missense	distal	-7	no	1.986	1.970	EPSD	COSMIC	1.791	Down-regulation
CAMK_PKD_PRKD2_ST	Q7KZI7	MARK2	Q9BZL6	PRKD2	S698	R691L	691	Missense	distal	-7	no	1.986	1.922	EPSD	COSMIC	1.791	Down-regulation
CAMK_PKD_PRKD2_ST	Q7KZI7	MARK2	Q9BZL6	PRKD2	S698	R691C	691	Missense	distal	-7	no	1.986	1.967	EPSD	COSMIC	1.791	Down-regulation
CAMK_PKD_PRKD2_ST	Q7KZI7	MARK2	Q9BZL6	PRKD2	S698	T696M	696	Missense	proximal	-2	no	1.986	1.963	EPSD	COSMIC	1.791	Down-regulation
CAMK_PKD_PRKD2_ST	Q9UBF8	PI4KB	Q9BZL6	PRKD2	S205	L210I	210	Missense	distal	5	no	2.578	2.588	EPSD	COSMIC	1.791	Up-regulation
CAMK_PKD_PRKD2_ST	Q9UBF8	PI4KB	Q9BZL6	PRKD2	S205	Q211K	211	Missense	distal	6	no	2.578	2.605	EPSD	COSMIC	1.791	Up-regulation
CAMK_PKD_PRKD2_ST	Q9UBF8	PI4KB	Q9BZL6	PRKD2	S205	H200Q	200	Missense	distal	-5	no	2.578	2.757	EPSD	COSMIC	1.791	Up-regulation
CAMK_PKD_PRKD2_ST	Q9UBF8	PI4KB	Q9BZL6	PRKD2	S205	R203H	203	Missense	proximal	-2	no	2.578	2.349	EPSD	COSMIC	1.791	Down-regulation
CAMK_PKD_PRKD2_ST	Q9UBF8	PI4KB	Q9BZL6	PRKD2	S205	Q204H	204	Missense	proximal	-1	no	2.578	2.550	EPSD	COSMIC	1.791	Down-regulation
CAMK_PKD_PRKD2_ST	Q9UBF8	PI4KB	Q9BZL6	PRKD2	S205	S209F	209	Missense	distal	4	no	2.578	2.920	EPSD	COSMIC	1.791	Up-regulation
CAMK_PKD_PRKD2_ST	Q9UBF8	PI4KB	Q9BZL6	PRKD2	S205	R203L	203	Missense	proximal	-2	no	2.578	2.298	EPSD	COSMIC	1.791	Down-regulation
CAMK_PKD_PRKD2_ST	Q9UBF8	PI4KB	Q9BZL6	PRKD2	S277	R270M	270	Missense	distal	-7	no	2.113	2.128	EPSD	COSMIC	1.791	Up-regulation
CAMK_PKD_PRKD2_ST	Q9UBF8	PI4KB	Q9BZL6	PRKD2	S277	S284G	284	Missense	distal	7	no	2.113	2.180	EPSD	COSMIC	1.791	Up-regulation
CAMK_PKD_PRKD2_ST	Q9UBF8	PI4KB	Q9BZL6	PRKD2	S277	R274C	274	Missense	distal	-3	no	2.113	1.265	EPSD	COSMIC	1.791	Loss
CAMK_PKD_PRKD2_ST	Q9UBF8	PI4KB	Q9BZL6	PRKD2	S277	R274H	274	Missense	distal	-3	no	2.113	0.960	EPSD	COSMIC	1.791	Loss
CAMK_PKD_PRKD2_ST	Q9UBF8	PI4KB	Q9BZL6	PRKD2	S294	S294I	294	Missense	central	0	yes	3.105	0.000	PhosphoSitePlus	COSMIC	1.791	Loss
CAMK_PKD_PRKD2_ST	Q9UBF8	PI4KB	Q9BZL6	PRKD2	S294	E301K	301	Missense	distal	7	no	3.105	3.099	PhosphoSitePlus	COSMIC	1.791	Down-regulation
CAMK_PKD_PRKD2_ST	Q9UBF8	PI4KB	Q9BZL6	PRKD2	S294	E301Q	301	Missense	distal	7	no	3.105	3.108	PhosphoSitePlus	COSMIC	1.791	Up-regulation
CAMK_PKD_PRKD2_ST	Q9UBF8	PI4KB	Q9BZL6	PRKD2	S307	S311R	311	Missense	distal	4	no	1.696	1.980	EPSD	COSMIC	1.791	Gain
CAMK_PKD_PRKD2_ST	Q9UBF8	PI4KB	Q9BZL6	PRKD2	T341	T341M	341	Missense	central	0	yes	2.305	0.000	EPSD	COSMIC	1.791	Loss
CAMK_PKD_PRKD2_ST	Q9UBF8	PI4KB	Q9BZL6	PRKD2	T341	L342V	342	Missense	proximal	1	no	2.305	2.254	EPSD	COSMIC	1.791	Down-regulation
CAMK_PKD_PRKD2_ST	Q9UBF8	PI4KB	Q9BZL6	PRKD2	T341	R338L	338	Missense	distal	-3	no	2.305	0.937	EPSD	COSMIC	1.791	Loss
CAMK_PKD_PRKD2_ST	Q9UBF8	PI4KB	Q9BZL6	PRKD2	T341	G336D	336	Missense	distal	-5	no	2.305	2.244	EPSD	COSMIC	1.791	Down-regulation
CAMK_PKD_PRKD2_ST	Q9UBF8	PI4KB	Q9BZL6	PRKD2	S425	R424Q	424	Missense	proximal	-1	no	1.726	1.829	EPSD	COSMIC	1.791	Gain
CAMK_PKD_PRKD2_ST	Q9UBF8	PI4KB	Q9BZL6	PRKD2	S425	E420K	420	Missense	distal	-5	no	1.726	2.183	EPSD	COSMIC	1.791	Gain
CAMK_PKD_PRKD2_ST	Q9UBF8	PI4KB	Q9BZL6	PRKD2	S425	R424L	424	Missense	proximal	-1	no	1.726	1.906	EPSD	COSMIC	1.791	Gain
CAMK_PKD_PRKD2_ST	Q9UBF8	PI4KB	Q9BZL6	PRKD2	S425	E420V	420	Missense	distal	-5	no	1.726	2.226	EPSD	COSMIC	1.791	Gain
CAMK_PKD_PRKD2_ST	Q9UBF8	PI4KB	Q9BZL6	PRKD2	S511	R509H	509	Missense	proximal	-2	no	2.376	2.147	EPSD	COSMIC	1.791	Down-regulation
CAMK_PKD_PRKD2_ST	Q9UBF8	PI4KB	Q9BZL6	PRKD2	S511	D505G	505	Missense	distal	-6	no	2.376	2.370	EPSD	COSMIC	1.791	Down-regulation
CAMK_PKD_PRKD2_ST	Q9UBF8	PI4KB	Q9BZL6	PRKD2	S511	P518S	518	Missense	distal	7	no	2.376	2.317	EPSD	COSMIC	1.791	Down-regulation
CAMK_PKD_PRKD2_ST	Q9UBF8	PI4KB	Q9BZL6	PRKD2	S511	R507H	507	Missense	distal	-4	no	2.376	2.370	EPSD	COSMIC	1.791	Down-regulation
CAMK_PKD_PRKD2_ST	Q9UBF8	PI4KB	Q9BZL6	PRKD2	S511	L514Q	514	Missense	distal	3	no	2.376	2.357	EPSD	COSMIC	1.791	Down-regulation
CAMK_PKD_PRKD2_ST	Q9UBF8	PI4KB	Q9BZL6	PRKD2	S511	R509C	509	Missense	proximal	-2	no	2.376	2.198	EPSD	COSMIC	1.791	Down-regulation
CAMK_PKD_PRKD2_ST	Q9UBF8	PI4KB	Q9BZL6	PRKD2	S511	R508L	508	Missense	distal	-3	no	2.376	1.008	EPSD	COSMIC	1.791	Loss
CAMK_PKD_PRKD2_ST	Q01105	SET	Q9BZL6	PRKD2	S63	E64Q	64	Missense	proximal	1	no	1.965	2.055	EPSD	COSMIC	1.791	Up-regulation
CAMK_PKD_PRKD2_ST	Q01105	SET	Q9BZL6	PRKD2	S184	S184I	184	Missense	central	0	yes	3.687	0.000	EPSD	COSMIC	1.791	Loss
CAMK_PKD_PRKD2_ST	Q01105	SET	Q9BZL6	PRKD2	S184	A190V	190	Missense	distal	6	no	3.687	3.626	EPSD	COSMIC	1.791	Down-regulation
CAMK_PKD_PRKD2_ST	Q01105	SET	Q9BZL6	PRKD2	S201	F202L	202	Missense	proximal	1	no	2.143	2.358	EPSD	COSMIC	1.791	Up-regulation
CAMK_PKD_PRKD2_ST	Q9BZL6	PRKD2	Q9BZL6	PRKD2	S111	Q116E	116	Missense	distal	5	no	1.864	1.846	EPSD	COSMIC	1.791	Down-regulation
CAMK_PKD_PRKD2_ST	Q9BZL6	PRKD2	Q9BZL6	PRKD2	S197	S203I	203	Missense	distal	6	no	2.449	2.305	EPSD	COSMIC	1.791	Down-regulation
CAMK_PKD_PRKD2_ST	Q9BZL6	PRKD2	Q9BZL6	PRKD2	S197	R195S	195	Missense	proximal	-2	no	2.449	2.335	EPSD	COSMIC	1.791	Down-regulation
CAMK_PKD_PRKD2_ST	Q9BZL6	PRKD2	Q9BZL6	PRKD2	S197	A202V	202	Missense	distal	5	no	2.449	2.429	EPSD	COSMIC	1.791	Down-regulation
CAMK_PKD_PRKD2_ST	Q9BZL6	PRKD2	Q9BZL6	PRKD2	S197	S203C	203	Missense	distal	6	no	2.449	2.301	EPSD	COSMIC	1.791	Down-regulation
CAMK_PKD_PRKD2_ST	Q9BZL6	PRKD2	Q9BZL6	PRKD2	S206	S203I	203	Missense	distal	-3	no	1.819	1.847	EPSD	COSMIC	1.791	Up-regulation
CAMK_PKD_PRKD2_ST	Q9BZL6	PRKD2	Q9BZL6	PRKD2	S206	A202V	202	Missense	distal	-4	no	1.819	1.830	EPSD	COSMIC	1.791	Up-regulation
CAMK_PKD_PRKD2_ST	Q9BZL6	PRKD2	Q9BZL6	PRKD2	S206	S203C	203	Missense	distal	-3	no	1.819	1.953	EPSD	COSMIC	1.791	Up-regulation
CAMK_PKD_PRKD2_ST	Q9BZL6	PRKD2	Q9BZL6	PRKD2	S223	E220K	220	Missense	distal	-3	no	2.366	2.439	EPSD	COSMIC	1.791	Up-regulation
CAMK_PKD_PRKD2_ST	Q9BZL6	PRKD2	Q9BZL6	PRKD2	T227	R232H	232	Missense	distal	5	no	2.443	2.461	EPSD	COSMIC	1.791	Up-regulation
CAMK_PKD_PRKD2_ST	Q9BZL6	PRKD2	Q9BZL6	PRKD2	T227	E220K	220	Missense	distal	-7	no	2.443	2.457	EPSD	COSMIC	1.791	Up-regulation
CAMK_PKD_PRKD2_ST	Q9BZL6	PRKD2	Q9BZL6	PRKD2	T227	R232L	232	Missense	distal	5	no	2.443	2.471	EPSD	COSMIC	1.791	Up-regulation
CAMK_PKD_PRKD2_ST	Q9BZL6	PRKD2	Q9BZL6	PRKD2	S236	S237F	237	Missense	proximal	1	no	1.866	1.547	EPSD	COSMIC	1.791	Loss
CAMK_PKD_PRKD2_ST	Q9BZL6	PRKD2	Q9BZL6	PRKD2	S236	R232H	232	Missense	distal	-4	no	1.866	1.860	EPSD	COSMIC	1.791	Down-regulation
CAMK_PKD_PRKD2_ST	Q9BZL6	PRKD2	Q9BZL6	PRKD2	S236	S239F	239	Missense	distal	3	no	1.866	1.917	EPSD	COSMIC	1.791	Up-regulation
CAMK_PKD_PRKD2_ST	Q9BZL6	PRKD2	Q9BZL6	PRKD2	S236	S241Y	241	Missense	distal	5	no	1.866	1.842	EPSD	COSMIC	1.791	Down-regulation
CAMK_PKD_PRKD2_ST	Q9BZL6	PRKD2	Q9BZL6	PRKD2	S236	R232L	232	Missense	distal	-4	no	1.866	1.860	EPSD	COSMIC	1.791	Down-regulation
CAMK_PKD_PRKD2_ST	Q9BZL6	PRKD2	Q9BZL6	PRKD2	S244	R249S	249	Missense	distal	5	no	2.068	2.119	EPSD	COSMIC	1.791	Up-regulation
CAMK_PKD_PRKD2_ST	Q9BZL6	PRKD2	Q9BZL6	PRKD2	S244	S237F	237	Missense	distal	-7	no	2.068	1.922	EPSD	COSMIC	1.791	Down-regulation
CAMK_PKD_PRKD2_ST	Q9BZL6	PRKD2	Q9BZL6	PRKD2	S244	S239F	239	Missense	distal	-5	no	2.068	1.994	EPSD	COSMIC	1.791	Down-regulation
CAMK_PKD_PRKD2_ST	Q9BZL6	PRKD2	Q9BZL6	PRKD2	S244	S241Y	241	Missense	distal	-3	no	2.068	2.142	EPSD	COSMIC	1.791	Up-regulation
CAMK_PKD_PRKD2_ST	Q9BZL6	PRKD2	Q9BZL6	PRKD2	S374	S374G	374	Missense	central	0	yes	1.876	0.000	EPSD	COSMIC	1.791	Loss
CAMK_PKD_PRKD2_ST	Q9BZL6	PRKD2	Q9BZL6	PRKD2	S374	L376V	376	Missense	proximal	2	no	1.876	1.877	EPSD	COSMIC	1.791	Up-regulation
CAMK_PKD_PRKD2_ST	Q9BZL6	PRKD2	Q9BZL6	PRKD2	S374	G367V	367	Missense	distal	-7	no	1.876	1.875	EPSD	COSMIC	1.791	Down-regulation
CAMK_PKD_PRKD2_ST	Q9BZL6	PRKD2	Q9BZL6	PRKD2	T392	T397N	397	Missense	distal	5	no	1.991	1.993	EPSD	COSMIC	1.791	Up-regulation
CAMK_PKD_PRKD2_ST	Q9BZL6	PRKD2	Q9BZL6	PRKD2	T392	L399P	399	Missense	distal	7	no	1.991	1.987	EPSD	COSMIC	1.791	Down-regulation
CAMK_PKD_PRKD2_ST	Q9BZL6	PRKD2	Q9BZL6	PRKD2	T392	R389L	389	Missense	distal	-3	no	1.991	0.622	EPSD	COSMIC	1.791	Loss
CAMK_PKD_PRKD2_ST	Q9BZL6	PRKD2	Q9BZL6	PRKD2	T392	V385E	385	Missense	distal	-7	no	1.991	2.057	EPSD	COSMIC	1.791	Up-regulation
CAMK_PKD_PRKD2_ST	Q9BZL6	PRKD2	Q9BZL6	PRKD2	T392	Q386K	386	Missense	distal	-6	no	1.991	1.988	EPSD	COSMIC	1.791	Down-regulation
CAMK_PKD_PRKD2_ST	Q9BZL6	PRKD2	Q9BZL6	PRKD2	T392	T391M	391	Missense	proximal	-1	no	1.991	2.000	EPSD	COSMIC	1.791	Up-regulation
CAMK_PKD_PRKD2_ST	Q9BZL6	PRKD2	Q9BZL6	PRKD2	S396	T397N	397	Missense	proximal	1	no	1.906	1.875	EPSD	COSMIC	1.791	Down-regulation
CAMK_PKD_PRKD2_ST	Q9BZL6	PRKD2	Q9BZL6	PRKD2	S396	L399P	399	Missense	distal	3	no	1.906	1.897	EPSD	COSMIC	1.791	Down-regulation
CAMK_PKD_PRKD2_ST	Q9BZL6	PRKD2	Q9BZL6	PRKD2	S396	R389L	389	Missense	distal	-7	no	1.906	1.842	EPSD	COSMIC	1.791	Down-regulation
CAMK_PKD_PRKD2_ST	Q9BZL6	PRKD2	Q9BZL6	PRKD2	S396	T391M	391	Missense	distal	-5	no	1.906	1.988	EPSD	COSMIC	1.791	Up-regulation
CAMK_PKD_PRKD2_ST	Q9BZL6	PRKD2	Q9BZL6	PRKD2	S529	A523T	523	Missense	distal	-6	no	2.224	2.226	EPSD	COSMIC;GDSC	1.791	Up-regulation
CAMK_PKD_PRKD2_ST	Q9BZL6	PRKD2	Q9BZL6	PRKD2	S710	F707L	707	Missense	distal	-3	no	3.496	3.112	EPSD	COSMIC	1.791	Down-regulation
CAMK_PKD_PRKD2_ST	Q9BZL6	PRKD2	Q9BZL6	PRKD2	S710	G703D	703	Missense	distal	-7	no	3.496	3.515	EPSD	COSMIC	1.791	Up-regulation
CAMK_PKD_PRKD2_ST	Q9BZL6	PRKD2	Q9BZL6	PRKD2	S710	G713R	713	Missense	distal	3	no	3.496	3.514	EPSD	COSMIC	1.791	Up-regulation
CAMK_PKD_PRKD2_ST	Q9BZL6	PRKD2	Q9BZL6	PRKD2	S710	G713E	713	Missense	distal	3	no	3.496	3.484	EPSD	COSMIC	1.791	Down-regulation
CAMK_PKD_PRKD2_ST	Q9BZL6	PRKD2	Q9BZL6	PRKD2	S876	G870E	870	Missense	distal	-6	no	2.335	2.339	PhosphoSitePlus	COSMIC	1.791	Up-regulation
CAMK_PKD_PRKD2_ST	Q9BZL6	PRKD2	Q9BZL6	PRKD2	S876	S876G	876	Missense	central	0	yes	2.335	0.000	PhosphoSitePlus	COSMIC	1.791	Loss
CAMK_PKD_PRKD2_ST	Q9BZL6	PRKD2	Q9BZL6	PRKD2	S876	G870R	870	Missense	distal	-6	no	2.335	2.344	PhosphoSitePlus	COSMIC	1.791	Up-regulation
CAMK_PKD_PRKD2_ST	Q9BZL6	PRKD2	Q9BZL6	PRKD2	S876	A872V	872	Missense	distal	-4	no	2.335	2.346	PhosphoSitePlus	COSMIC	1.791	Up-regulation
CAMK_PKD_PRKD2_ST	P16144	ITGB4	Q9BZL6	PRKD2	S139	S139C	139	Missense	central	0	yes	2.381	0.000	EPSD	COSMIC	1.791	Loss
CAMK_PKD_PRKD2_ST	P16144	ITGB4	Q9BZL6	PRKD2	T210	N205S	205	Missense	distal	-5	no	1.994	1.997	EPSD	COSMIC	1.791	Up-regulation
CAMK_PKD_PRKD2_ST	P16144	ITGB4	Q9BZL6	PRKD2	T210	K204N	204	Missense	distal	-6	no	1.994	2.004	EPSD	COSMIC	1.791	Up-regulation
CAMK_PKD_PRKD2_ST	P16144	ITGB4	Q9BZL6	PRKD2	S368	A374S	374	Missense	distal	6	no	2.612	2.706	EPSD	COSMIC	1.791	Up-regulation
CAMK_PKD_PRKD2_ST	P16144	ITGB4	Q9BZL6	PRKD2	S368	R367L	367	Missense	proximal	-1	no	2.612	2.793	EPSD	COSMIC	1.791	Up-regulation
CAMK_PKD_PRKD2_ST	P16144	ITGB4	Q9BZL6	PRKD2	S1084	Q1082H	1082	Missense	proximal	-2	no	2.192	2.142	EPSD	COSMIC	1.791	Down-regulation
CAMK_PKD_PRKD2_ST	P16144	ITGB4	Q9BZL6	PRKD2	S1345	G1340W	1340	Missense	distal	-5	no	1.897	1.937	EPSD	COSMIC	1.791	Up-regulation
CAMK_PKD_PRKD2_ST	P16144	ITGB4	Q9BZL6	PRKD2	S1358	V1353I	1353	Missense	distal	-5	no	3.017	3.151	EPSD	COSMIC	1.791	Up-regulation
CAMK_PKD_PRKD2_ST	P16144	ITGB4	Q9BZL6	PRKD2	S1358	V1365I	1365	Missense	distal	7	no	3.017	3.004	EPSD	COSMIC;GDSC	1.791	Down-regulation
CAMK_PKD_PRKD2_ST	P16144	ITGB4	Q9BZL6	PRKD2	T1463	T1462N	1462	Missense	proximal	-1	no	2.253	2.247	EPSD	COSMIC	1.791	Down-regulation
CAMK_PKD_PRKD2_ST	P16144	ITGB4	Q9BZL6	PRKD2	T1463	S1457Y	1457	Missense	distal	-6	no	2.253	2.273	EPSD	COSMIC	1.791	Up-regulation
CAMK_PKD_PRKD2_ST	P16144	ITGB4	Q9BZL6	PRKD2	T1463	M1461V	1461	Missense	proximal	-2	no	2.253	2.213	EPSD	COSMIC	1.791	Down-regulation
CAMK_PKD_PRKD2_ST	P16144	ITGB4	Q9BZL6	PRKD2	S1483	V1481M	1481	Missense	proximal	-2	no	2.512	2.551	EPSD	COSMIC	1.791	Up-regulation
CAMK_PKD_PRKD2_ST	P16144	ITGB4	Q9BZL6	PRKD2	S1483	V1477M	1477	Missense	distal	-6	no	2.512	2.504	EPSD	COSMIC	1.791	Down-regulation
CAMK_PKD_PRKD2_ST	P16144	ITGB4	Q9BZL6	PRKD2	S1483	L1488F	1488	Missense	distal	5	no	2.512	2.487	EPSD	COSMIC	1.791	Down-regulation
CAMK_PKD_PRKD2_ST	P16144	ITGB4	Q9BZL6	PRKD2	T1487	V1481M	1481	Missense	distal	-6	no	1.840	1.833	EPSD	COSMIC	1.791	Down-regulation
CAMK_PKD_PRKD2_ST	P16144	ITGB4	Q9BZL6	PRKD2	T1487	L1488F	1488	Missense	proximal	1	no	1.840	1.624	EPSD	COSMIC	1.791	Loss
CAMK_PKD_PRKD2_ST	P16144	ITGB4	Q9BZL6	PRKD2	S1511	Y1510C	1510	Missense	proximal	-1	no	3.025	3.038	EPSD	COSMIC	1.791	Up-regulation
CAMK_PKD_PRKD2_ST	P16144	ITGB4	Q9BZL6	PRKD2	S1511	S1511F	1511	Missense	central	0	yes	3.025	0.000	EPSD	COSMIC	1.791	Loss
CAMK_PKD_PRKD2_ST	P16144	ITGB4	Q9BZL6	PRKD2	S1604	R1601Q	1601	Missense	distal	-3	no	2.353	1.279	EPSD	COSMIC;CCLE	1.791	Loss
CAMK_PKD_PRKD2_ST	P16144	ITGB4	Q9BZL6	PRKD2	T1721	G1725R	1725	Missense	distal	4	no	2.114	2.010	EPSD	COSMIC	1.791	Down-regulation
CAMK_PKD_PRKD2_ST	P16144	ITGB4	Q9BZL6	PRKD2	S1761	H1754Q	1754	Missense	distal	-7	no	1.902	1.942	EPSD	COSMIC	1.791	Up-regulation
CAMK_PKD_PRKD2_ST	P16144	ITGB4	Q9BZL6	PRKD2	S1791	R1794P	1794	Missense	distal	3	no	1.912	1.884	EPSD	COSMIC;CCLE	1.791	Down-regulation
CAMK_PKD_PRKD2_ST	P16144	ITGB4	Q9BZL6	PRKD2	S1791	Q1798H	1798	Missense	distal	7	no	1.912	1.932	EPSD	COSMIC	1.791	Up-regulation
CAMK_PKD_PRKD2_ST	P16144	ITGB4	Q9BZL6	PRKD2	T1797	R1794P	1794	Missense	distal	-3	no	2.609	1.562	EPSD	COSMIC;CCLE	1.791	Loss
CAMK_PKD_PRKD2_ST	P16144	ITGB4	Q9BZL6	PRKD2	T1797	S1802R	1802	Missense	distal	5	no	2.609	2.558	EPSD	COSMIC	1.791	Down-regulation
CAMK_PKD_PRKD2_ST	P16144	ITGB4	Q9BZL6	PRKD2	T1797	Q1798H	1798	Missense	proximal	1	no	2.609	2.565	EPSD	COSMIC	1.791	Down-regulation
CAMK_PKD_PRKD2_ST	P16144	ITGB4	Q9BZL6	PRKD2	T1806	S1802R	1802	Missense	distal	-4	no	2.846	2.872	EPSD	COSMIC	1.791	Up-regulation
CAMK_PKD_PRKD2_ST	Q13671	RIN1	Q9BZL6	PRKD2	S210	R209Q	209	Missense	proximal	-1	no	1.710	1.814	EPSD	COSMIC;CCLE	1.791	Gain
CAMK_PKD_PRKD2_ST	Q13671	RIN1	Q9BZL6	PRKD2	S255	R248H	248	Missense	distal	-7	no	2.005	1.989	EPSD	COSMIC	1.791	Down-regulation
CAMK_PKD_PRKD2_ST	Q13671	RIN1	Q9BZL6	PRKD2	S291	G294W	294	Missense	distal	3	no	2.183	2.181	EPSD	COSMIC;CCLE	1.791	Down-regulation
CAMK_PKD_PRKD2_ST	Q13671	RIN1	Q9BZL6	PRKD2	S292	G294W	294	Missense	proximal	2	no	3.868	3.867	PhosphoSitePlus	COSMIC;CCLE	1.791	Down-regulation
CAMK_PKD_PRKD2_ST	Q13671	RIN1	Q9BZL6	PRKD2	S337	R342C	342	Missense	distal	5	no	1.969	2.001	EPSD	COSMIC	1.791	Up-regulation
CAMK_PKD_PRKD2_ST	Q13671	RIN1	Q9BZL6	PRKD2	S351	L357Q	357	Missense	distal	6	no	2.587	2.715	EPSD	COSMIC	1.791	Up-regulation
CAMK_PKD_PRKD2_ST	Q13671	RIN1	Q9BZL6	PRKD2	S351	R348W	348	Missense	distal	-3	no	2.587	1.705	EPSD	COSMIC	1.791	Loss
CAMK_PKD_PRKD2_ST	Q13671	RIN1	Q9BZL6	PRKD2	S424	H430Y	430	Missense	distal	6	no	1.945	1.920	EPSD	COSMIC	1.791	Down-regulation
CAMK_PKD_PRKD2_ST	Q13671	RIN1	Q9BZL6	PRKD2	S424	H430Q	430	Missense	distal	6	no	1.945	1.980	EPSD	COSMIC	1.791	Up-regulation
CAMK_PKD_PRKD2_ST	Q13671	RIN1	Q9BZL6	PRKD2	S611	R608H	608	Missense	distal	-3	no	2.887	1.734	EPSD	COSMIC;GDSC	1.791	Loss
CAMK_PKD_PRKD2_ST	Q99828	CIB1	Q9BZL6	PRKD2	S78	S80P	80	Missense	proximal	2	no	3.471	3.457	PhosphoSitePlus	COSMIC	1.791	Down-regulation
CAMK_PKD_PRKD2_ST	Q99828	CIB1	Q9BZL6	PRKD2	S78	A82T	82	Missense	distal	4	no	3.471	3.584	PhosphoSitePlus	COSMIC	1.791	Up-regulation
CAMK_PKD_PRKD2_ST	Q99828	CIB1	Q9BZL6	PRKD2	S78	A82S	82	Missense	distal	4	no	3.471	3.392	PhosphoSitePlus	COSMIC	1.791	Down-regulation
CAMK_CAMK2_CAMK2B_ST	O14490	DLGAP1	Q13554	CAMK2B	S233	D229N	229	Missense	distal	-4	no	117.356	132.765	EPSD	COSMIC	127.946	Gain
CAMK_CAMK2_CAMK2B_ST	O14490	DLGAP1	Q13554	CAMK2B	S233	P228S	228	Missense	distal	-5	no	117.356	128.517	EPSD	COSMIC	127.946	Gain
CAMK_CAMK2_CAMK2B_ST	O14490	DLGAP1	Q13554	CAMK2B	S280	S277R	277	Missense	distal	-3	no	102.305	135.993	EPSD	COSMIC	127.946	Gain
CAMK_CAMK2_CAMK2B_ST	O14490	DLGAP1	Q13554	CAMK2B	S375	A371V	371	Missense	distal	-4	no	140.853	139.026	EPSD	COSMIC;GDSC;CCLE	127.946	Down-regulation
CAMK_CAMK2_CAMK2B_ST	O14490	DLGAP1	Q13554	CAMK2B	S375	L377F	377	Missense	proximal	2	no	140.853	131.583	EPSD	COSMIC	127.946	Down-regulation
CAMK_CAMK2_CAMK2B_ST	O14490	DLGAP1	Q13554	CAMK2B	S375	E374D	374	Missense	proximal	-1	no	140.853	134.019	EPSD	COSMIC	127.946	Down-regulation
CAMK_CAMK2_CAMK2B_ST	O14490	DLGAP1	Q13554	CAMK2B	S383	L384I	384	Missense	proximal	1	no	129.041	136.520	EPSD	COSMIC	127.946	Up-regulation
CAMK_CAMK2_CAMK2B_ST	O14490	DLGAP1	Q13554	CAMK2B	S383	L377F	377	Missense	distal	-6	no	129.041	128.857	EPSD	COSMIC	127.946	Down-regulation
CAMK_CAMK2_CAMK2B_ST	O14490	DLGAP1	Q13554	CAMK2B	S383	T388K	388	Missense	distal	5	no	129.041	129.789	EPSD	COSMIC	127.946	Up-regulation
CAMK_CAMK2_CAMK2B_ST	O14490	DLGAP1	Q13554	CAMK2B	T388	S393Y	393	Missense	distal	5	no	125.378	128.227	EPSD	COSMIC	127.946	Gain
CAMK_CAMK2_CAMK2B_ST	O14490	DLGAP1	Q13554	CAMK2B	S440	R435C	435	Missense	distal	-5	no	148.104	130.482	EPSD	COSMIC	127.946	Down-regulation
CAMK_CAMK2_CAMK2B_ST	O14490	DLGAP1	Q13554	CAMK2B	S503	R496W	496	Missense	distal	-7	no	137.801	133.902	EPSD	COSMIC;GDSC;CCLE	127.946	Down-regulation
CAMK_CAMK2_CAMK2B_ST	O14490	DLGAP1	Q13554	CAMK2B	S503	S510F	510	Missense	distal	7	no	137.801	142.253	EPSD	COSMIC	127.946	Up-regulation
CAMK_CAMK2_CAMK2B_ST	O14490	DLGAP1	Q13554	CAMK2B	S503	R496Q	496	Missense	distal	-7	no	137.801	137.785	EPSD	COSMIC	127.946	Down-regulation
CAMK_CAMK2_CAMK2B_ST	O14490	DLGAP1	Q13554	CAMK2B	S503	I498T	498	Missense	distal	-5	no	137.801	130.402	EPSD	COSMIC	127.946	Down-regulation
CAMK_CAMK2_CAMK2B_ST	O14490	DLGAP1	Q13554	CAMK2B	S503	E499A	499	Missense	distal	-4	no	137.801	138.043	EPSD	COSMIC	127.946	Up-regulation
CAMK_CAMK2_CAMK2B_ST	O14490	DLGAP1	Q13554	CAMK2B	S503	R496S	496	Missense	distal	-7	no	137.801	136.532	EPSD	COSMIC	127.946	Down-regulation
CAMK_CAMK2_CAMK2B_ST	O14490	DLGAP1	Q13554	CAMK2B	S503	R496H	496	Missense	distal	-7	no	137.801	132.574	EPSD	COSMIC	127.946	Down-regulation
CAMK_CAMK2_CAMK2B_ST	O14490	DLGAP1	Q13554	CAMK2B	S528	V523I	523	Missense	distal	-5	no	125.954	136.072	EPSD	COSMIC	127.946	Gain
CAMK_CAMK2_CAMK2B_ST	O14490	DLGAP1	Q13554	CAMK2B	S562	A569V	569	Missense	distal	7	no	128.558	125.481	EPSD	COSMIC	127.946	Loss
CAMK_CAMK2_CAMK2B_ST	O14490	DLGAP1	Q13554	CAMK2B	S562	A559D	559	Missense	distal	-3	no	128.558	132.235	EPSD	COSMIC	127.946	Up-regulation
CAMK_CAMK2_CAMK2B_ST	O14490	DLGAP1	Q13554	CAMK2B	S562	A559G	559	Missense	distal	-3	no	128.558	130.122	EPSD	COSMIC	127.946	Up-regulation
CAMK_CAMK2_CAMK2B_ST	O14490	DLGAP1	Q13554	CAMK2B	S589	T590I	590	Missense	proximal	1	no	129.687	129.537	EPSD	COSMIC;GDSC	127.946	Down-regulation
CAMK_CAMK2_CAMK2B_ST	O14490	DLGAP1	Q13554	CAMK2B	S589	M596I	596	Missense	distal	7	no	129.687	130.748	EPSD	COSMIC	127.946	Up-regulation
CAMK_CAMK2_CAMK2B_ST	O14490	DLGAP1	Q13554	CAMK2B	S589	S584F	584	Missense	distal	-5	no	129.687	118.482	EPSD	COSMIC	127.946	Loss
CAMK_CAMK2_CAMK2B_ST	O14490	DLGAP1	Q13554	CAMK2B	S589	L586I	586	Missense	distal	-3	no	129.687	126.796	EPSD	COSMIC	127.946	Loss
CAMK_CAMK2_CAMK2B_ST	O14490	DLGAP1	Q13554	CAMK2B	S592	T590I	590	Missense	proximal	-2	no	132.614	122.011	EPSD	COSMIC;GDSC	127.946	Loss
CAMK_CAMK2_CAMK2B_ST	O14490	DLGAP1	Q13554	CAMK2B	S592	M596I	596	Missense	distal	4	no	132.614	133.525	EPSD	COSMIC	127.946	Up-regulation
CAMK_CAMK2_CAMK2B_ST	O14490	DLGAP1	Q13554	CAMK2B	S592	L586I	586	Missense	distal	-6	no	132.614	134.842	EPSD	COSMIC	127.946	Up-regulation
CAMK_CAMK2_CAMK2B_ST	O14490	DLGAP1	Q13554	CAMK2B	S595	T590I	590	Missense	distal	-5	no	145.617	153.016	EPSD	COSMIC;GDSC	127.946	Up-regulation
CAMK_CAMK2_CAMK2B_ST	O14490	DLGAP1	Q13554	CAMK2B	S595	M596I	596	Missense	proximal	1	no	145.617	138.881	EPSD	COSMIC	127.946	Down-regulation
CAMK_CAMK2_CAMK2B_ST	O14490	DLGAP1	Q13554	CAMK2B	S595	A602D	602	Missense	distal	7	no	145.617	145.956	EPSD	COSMIC	127.946	Up-regulation
CAMK_CAMK2_CAMK2B_ST	O14490	DLGAP1	Q13554	CAMK2B	S651	R648S	648	Missense	distal	-3	no	141.216	107.529	EPSD	COSMIC	127.946	Loss
CAMK_CAMK2_CAMK2B_ST	O14490	DLGAP1	Q13554	CAMK2B	S651	D657G	657	Missense	distal	6	no	141.216	141.540	EPSD	COSMIC	127.946	Up-regulation
CAMK_CAMK2_CAMK2B_ST	O14490	DLGAP1	Q13554	CAMK2B	S651	Q655H	655	Missense	distal	4	no	141.216	140.076	EPSD	COSMIC	127.946	Down-regulation
CAMK_CAMK2_CAMK2B_ST	O14490	DLGAP1	Q13554	CAMK2B	S651	S651F	651	Missense	central	0	yes	141.216	0.000	EPSD	COSMIC	127.946	Loss
CAMK_CAMK2_CAMK2B_ST	O14490	DLGAP1	Q13554	CAMK2B	S695	T698K	698	Missense	distal	3	no	139.671	139.677	EPSD	COSMIC	127.946	Up-regulation
CAMK_CAMK2_CAMK2B_ST	O14490	DLGAP1	Q13554	CAMK2B	S695	V700I	700	Missense	distal	5	no	139.671	139.912	EPSD	COSMIC	127.946	Up-regulation
CAMK_CAMK2_CAMK2B_ST	O14490	DLGAP1	Q13554	CAMK2B	S695	A699E	699	Missense	distal	4	no	139.671	138.916	EPSD	COSMIC	127.946	Down-regulation
CAMK_CAMK2_CAMK2B_ST	Q13131	PRKAA1	Q13554	CAMK2B	S486	A484D	484	Missense	proximal	-2	no	137.013	130.210	EPSD	COSMIC	127.946	Down-regulation
CAMK_CAMK2_CAMK2B_ST	Q13131	PRKAA1	Q13554	CAMK2B	S496	V497A	497	Missense	proximal	1	no	151.709	142.880	EPSD	COSMIC	127.946	Down-regulation
CAMK_CAMK2_CAMK2B_ST	Q13131	PRKAA1	Q13554	CAMK2B	S496	R501G	501	Missense	distal	5	no	151.709	152.460	EPSD	COSMIC	127.946	Up-regulation
CAMK_CAMK2_CAMK2B_ST	Q16625	OCLN	Q13554	CAMK2B	T305	V308M	308	Missense	distal	3	no	136.260	136.363	EPSD	COSMIC;GDSC	127.946	Up-regulation
CAMK_CAMK2_CAMK2B_ST	Q16625	OCLN	Q13554	CAMK2B	T305	K299N	299	Missense	distal	-6	no	136.260	136.841	EPSD	COSMIC	127.946	Up-regulation
CAMK_CAMK2_CAMK2B_ST	Q16625	OCLN	Q13554	CAMK2B	T305	V308A	308	Missense	distal	3	no	136.260	136.491	EPSD	COSMIC	127.946	Up-regulation
CAMK_CAMK2_CAMK2B_ST	Q13555	CAMK2G	Q13554	CAMK2B	S36	R29C	29	Missense	distal	-7	no	138.642	133.145	EPSD	COSMIC	127.946	Down-regulation
CAMK_CAMK2_CAMK2B_ST	Q13555	CAMK2G	Q13554	CAMK2B	S280	R284H	284	Missense	distal	4	no	132.658	132.090	EPSD	COSMIC	127.946	Down-regulation
CAMK_CAMK2_CAMK2B_ST	Q13555	CAMK2G	Q13554	CAMK2B	T287	R284H	284	Missense	distal	-3	no	161.152	-20.216	PhosphoSitePlus	COSMIC	127.946	Loss
CAMK_CAMK2_CAMK2B_ST	Q13555	CAMK2G	Q13554	CAMK2B	T306	T306K	306	Missense	central	0	yes	147.183	0.000	EPSD	COSMIC	127.946	Loss
CAMK_CAMK2_CAMK2B_ST	Q13555	CAMK2G	Q13554	CAMK2B	T306	T306M	306	Missense	central	0	yes	147.183	0.000	EPSD	COSMIC	127.946	Loss
CAMK_CAMK2_CAMK2B_ST	Q13555	CAMK2G	Q13554	CAMK2B	T307	T306K	306	Missense	proximal	-1	no	160.341	164.587	EPSD	COSMIC	127.946	Up-regulation
CAMK_CAMK2_CAMK2B_ST	Q13555	CAMK2G	Q13554	CAMK2B	T307	T306M	306	Missense	proximal	-1	no	160.341	161.968	EPSD	COSMIC	127.946	Up-regulation
CAMK_CAMK2_CAMK2B_ST	Q13555	CAMK2G	Q13554	CAMK2B	S325	G327D	327	Missense	proximal	2	no	158.691	155.594	EPSD	COSMIC	127.946	Down-regulation
CAMK_CAMK2_CAMK2B_ST	Q13555	CAMK2G	Q13554	CAMK2B	S335	H339L	339	Missense	distal	4	no	176.809	177.138	EPSD	COSMIC	127.946	Up-regulation
CAMK_CAMK2_CAMK2B_ST	Q13555	CAMK2G	Q13554	CAMK2B	S337	H339L	339	Missense	proximal	2	no	154.684	157.434	EPSD	COSMIC	127.946	Up-regulation
CAMK_CAMK2_CAMK2B_ST	Q13555	CAMK2G	Q13554	CAMK2B	S381	D376Y	376	Missense	distal	-5	no	132.678	129.594	EPSD	COSMIC	127.946	Down-regulation
CAMK_CAMK2_CAMK2B_ST	Q13555	CAMK2G	Q13554	CAMK2B	S381	E383D	383	Missense	proximal	2	no	132.678	133.251	EPSD	COSMIC	127.946	Up-regulation
CAMK_CAMK2_CAMK2B_ST	Q13555	CAMK2G	Q13554	CAMK2B	S381	T387M	387	Missense	distal	6	no	132.678	131.409	EPSD	COSMIC	127.946	Down-regulation
CAMK_CAMK2_CAMK2B_ST	Q13555	CAMK2G	Q13554	CAMK2B	S381	T387A	387	Missense	distal	6	no	132.678	131.658	EPSD	COSMIC	127.946	Down-regulation
CAMK_CAMK2_CAMK2B_ST	P16949	STMN1	Q13554	CAMK2B	S16	R14C	14	Missense	proximal	-2	no	143.674	132.496	PhosphoSitePlus	COSMIC	127.946	Down-regulation
CAMK_CAMK2_CAMK2B_ST	P16949	STMN1	Q13554	CAMK2B	S16	Q18E	18	Missense	proximal	2	no	143.674	144.514	PhosphoSitePlus	COSMIC	127.946	Up-regulation
CAMK_CAMK2_CAMK2B_ST	P16949	STMN1	Q13554	CAMK2B	S46	D44N	44	Missense	proximal	-2	no	132.998	141.320	EPSD	COSMIC	127.946	Up-regulation
CAMK_CAMK2_CAMK2B_ST	P16949	STMN1	Q13554	CAMK2B	S63	R61S	61	Missense	proximal	-2	no	130.393	126.879	EPSD	COSMIC	127.946	Loss
STE_STE20_PAKB_PAK5_ST	P15976	GATA1	Q9P286	PAK5	S107	T108P	108	Missense	proximal	1	no	4.412	4.387	EPSD	COSMIC	3.202	Down-regulation
STE_STE20_PAKB_PAK5_ST	P15976	GATA1	Q9P286	PAK5	S107	R113S	113	Missense	distal	6	no	4.412	4.423	EPSD	COSMIC	3.202	Up-regulation
STE_STE20_PAKB_PAK5_ST	P15976	GATA1	Q9P286	PAK5	S107	R113C	113	Missense	distal	6	no	4.412	4.402	EPSD	COSMIC;GDSC;CCLE	3.202	Down-regulation
STE_STE20_PAKB_PAK5_ST	P15976	GATA1	Q9P286	PAK5	S107	K100N	100	Missense	distal	-7	no	4.412	4.482	EPSD	COSMIC	3.202	Up-regulation
STE_STE20_PAKB_PAK5_ST	P15976	GATA1	Q9P286	PAK5	S107	R113L	113	Missense	distal	6	no	4.412	4.417	EPSD	COSMIC	3.202	Up-regulation
STE_STE20_PAKB_PAK5_ST	P15976	GATA1	Q9P286	PAK5	S107	R113H	113	Missense	distal	6	no	4.412	4.409	EPSD	COSMIC	3.202	Down-regulation
STE_STE20_PAKB_PAK5_ST	P15976	GATA1	Q9P286	PAK5	S107	P105L	105	Missense	proximal	-2	no	4.412	4.411	EPSD	COSMIC	3.202	Down-regulation
STE_STE20_PAKB_PAK5_ST	P15976	GATA1	Q9P286	PAK5	S107	G102R	102	Missense	distal	-5	no	4.412	4.400	EPSD	COSMIC	3.202	Down-regulation
STE_STE20_PAKB_PAK5_ST	P15976	GATA1	Q9P286	PAK5	S107	V109L	109	Missense	proximal	2	no	4.412	4.342	EPSD	COSMIC	3.202	Down-regulation
STE_STE20_PAKB_PAK5_ST	P15976	GATA1	Q9P286	PAK5	S161	P166H	166	Missense	distal	5	no	7.382	7.379	PhosphoSitePlus;EPSD	COSMIC	3.202	Down-regulation
STE_STE20_PAKB_PAK5_ST	P15976	GATA1	Q9P286	PAK5	S161	F168V	168	Missense	distal	7	no	7.382	7.248	PhosphoSitePlus;EPSD	COSMIC	3.202	Down-regulation
STE_STE20_PAKB_PAK5_ST	P15976	GATA1	Q9P286	PAK5	S187	S182A	182	Missense	distal	-5	no	7.306	7.323	EPSD;PhosphoSitePlus	COSMIC	3.202	Up-regulation
STE_STE20_PAKB_PAK5_ST	P15976	GATA1	Q9P286	PAK5	T304	K308R	308	Missense	distal	4	no	3.260	3.216	EPSD	COSMIC	3.202	Down-regulation
STE_STE20_PAKB_PAK5_ST	P15976	GATA1	Q9P286	PAK5	T304	R307C	307	Missense	distal	3	no	3.260	3.237	EPSD	COSMIC;CCLE	3.202	Down-regulation
STE_STE20_PAKB_PAK5_ST	P15976	GATA1	Q9P286	PAK5	T304	N306S	306	Missense	proximal	2	no	3.260	3.197	EPSD	COSMIC	3.202	Loss
STE_STE20_PAKB_PAK5_ST	P15976	GATA1	Q9P286	PAK5	T304	D300N	300	Missense	distal	-4	no	3.260	3.280	EPSD	COSMIC	3.202	Up-regulation
STE_STE20_PAKB_PAK5_ST	P15976	GATA1	Q9P286	PAK5	S319	G318S	318	Missense	proximal	-1	no	2.971	3.255	EPSD	COSMIC	3.202	Gain
STE_STE20_PAKB_PAK5_ST	Q9P286	PAK5	Q9P286	PAK5	S223	P227L	227	Missense	distal	4	no	3.901	3.782	EPSD	COSMIC;GDSC	3.202	Down-regulation
STE_STE20_PAKB_PAK5_ST	Q9P286	PAK5	Q9P286	PAK5	S223	S223W	223	Missense	central	0	yes	3.901	0.000	EPSD	COSMIC	3.202	Loss
STE_STE20_PAKB_PAK5_ST	Q9P286	PAK5	Q9P286	PAK5	S223	R221K	221	Missense	proximal	-2	no	3.901	3.877	EPSD	COSMIC	3.202	Down-regulation
STE_STE20_PAKB_PAK5_ST	Q9P286	PAK5	Q9P286	PAK5	S223	Q220H	220	Missense	distal	-3	no	3.901	3.900	EPSD	COSMIC	3.202	Down-regulation
STE_STE20_PAKB_PAK5_ST	Q9P286	PAK5	Q9P286	PAK5	S223	D229N	229	Missense	distal	6	no	3.901	3.872	EPSD	COSMIC	3.202	Down-regulation
STE_STE20_PAKB_PAK5_ST	Q9P286	PAK5	Q9P286	PAK5	S223	E218K	218	Missense	distal	-5	no	3.901	3.893	EPSD	COSMIC	3.202	Down-regulation
STE_STE20_PAKB_PAK5_ST	Q9P286	PAK5	Q9P286	PAK5	S226	P227L	227	Missense	proximal	1	no	3.435	3.370	EPSD	COSMIC;GDSC	3.202	Down-regulation
STE_STE20_PAKB_PAK5_ST	Q9P286	PAK5	Q9P286	PAK5	S226	R221K	221	Missense	distal	-5	no	3.435	3.438	EPSD	COSMIC	3.202	Up-regulation
STE_STE20_PAKB_PAK5_ST	Q9P286	PAK5	Q9P286	PAK5	S226	Q220H	220	Missense	distal	-6	no	3.435	3.412	EPSD	COSMIC	3.202	Down-regulation
STE_STE20_PAKB_PAK5_ST	Q9P286	PAK5	Q9P286	PAK5	S226	D229N	229	Missense	distal	3	no	3.435	3.440	EPSD	COSMIC	3.202	Up-regulation
STE_STE20_PAKB_PAK5_ST	Q9P286	PAK5	Q9P286	PAK5	S226	S231L	231	Missense	distal	5	no	3.435	3.420	EPSD	COSMIC	3.202	Down-regulation
STE_STE20_PAKB_PAK5_ST	Q9P286	PAK5	Q9P286	PAK5	S237	T242N	242	Missense	distal	5	no	3.284	3.301	EPSD	COSMIC	3.202	Up-regulation
STE_STE20_PAKB_PAK5_ST	Q9P286	PAK5	Q9P286	PAK5	S237	S237F	237	Missense	central	0	yes	3.284	0.000	EPSD	COSMIC	3.202	Loss
STE_STE20_PAKB_PAK5_ST	Q9P286	PAK5	Q9P286	PAK5	S237	G241E	241	Missense	distal	4	no	3.284	3.273	EPSD	COSMIC	3.202	Down-regulation
STE_STE20_PAKB_PAK5_ST	Q9P286	PAK5	Q9P286	PAK5	S237	S243R	243	Missense	distal	6	no	3.284	3.273	EPSD	COSMIC	3.202	Down-regulation
STE_STE20_PAKB_PAK5_ST	Q9P286	PAK5	Q9P286	PAK5	S237	G241K	241	Missense	distal	4	no	3.284	3.300	EPSD	COSMIC	3.202	Up-regulation
STE_STE20_PAKB_PAK5_ST	Q9P286	PAK5	Q9P286	PAK5	S237	S231L	231	Missense	distal	-6	no	3.284	3.516	EPSD	COSMIC	3.202	Up-regulation
STE_STE20_PAKB_PAK5_ST	Q9P286	PAK5	Q9P286	PAK5	S237	G241R	241	Missense	distal	4	no	3.284	3.256	EPSD	COSMIC	3.202	Down-regulation
STE_STE20_PAKB_PAK5_ST	Q9P286	PAK5	Q9P286	PAK5	S237	P236L	236	Missense	proximal	-1	no	3.284	3.577	EPSD	COSMIC	3.202	Up-regulation
STE_STE20_PAKB_PAK5_ST	Q9P286	PAK5	Q9P286	PAK5	S237	G241W	241	Missense	distal	4	no	3.284	3.268	EPSD	COSMIC	3.202	Down-regulation
STE_STE20_PAKB_PAK5_ST	Q9P286	PAK5	Q9P286	PAK5	S237	T239N	239	Missense	proximal	2	no	3.284	3.239	EPSD	COSMIC	3.202	Down-regulation
STE_STE20_PAKB_PAK5_ST	Q9P286	PAK5	Q9P286	PAK5	S237	R238G	238	Missense	proximal	1	no	3.284	3.322	EPSD	COSMIC	3.202	Up-regulation
STE_STE20_PAKB_PAK5_ST	Q9P286	PAK5	Q9P286	PAK5	S237	P236S	236	Missense	proximal	-1	no	3.284	3.800	EPSD	COSMIC	3.202	Up-regulation
STE_STE20_PAKB_PAK5_ST	Q9P286	PAK5	Q9P286	PAK5	S271	P268S	268	Missense	distal	-3	no	3.457	3.459	EPSD	COSMIC	3.202	Up-regulation
STE_STE20_PAKB_PAK5_ST	Q9P286	PAK5	Q9P286	PAK5	S271	Y272F	272	Missense	proximal	1	no	3.457	3.343	EPSD	COSMIC	3.202	Down-regulation
STE_STE20_PAKB_PAK5_ST	Q9P286	PAK5	Q9P286	PAK5	S271	R266M	266	Missense	distal	-5	no	3.457	3.469	EPSD	COSMIC	3.202	Up-regulation
STE_STE20_PAKB_PAK5_ST	Q9P286	PAK5	Q9P286	PAK5	S271	P278H	278	Missense	distal	7	no	3.457	3.446	EPSD	COSMIC	3.202	Down-regulation
STE_STE20_PAKB_PAK5_ST	Q9P286	PAK5	Q9P286	PAK5	S271	R266K	266	Missense	distal	-5	no	3.457	3.460	EPSD	COSMIC	3.202	Up-regulation
STE_STE20_PAKB_PAK5_ST	Q9P286	PAK5	Q9P286	PAK5	S271	R266W	266	Missense	distal	-5	no	3.457	3.458	EPSD	COSMIC;GDSC	3.202	Up-regulation
STE_STE20_PAKB_PAK5_ST	Q9P286	PAK5	Q9P286	PAK5	S271	R267W	267	Missense	distal	-4	no	3.457	3.416	EPSD	COSMIC	3.202	Down-regulation
STE_STE20_PAKB_PAK5_ST	Q9P286	PAK5	Q9P286	PAK5	S271	S271L	271	Missense	central	0	yes	3.457	0.000	EPSD	COSMIC;GDSC	3.202	Loss
STE_STE20_PAKB_PAK5_ST	Q9P286	PAK5	Q9P286	PAK5	S271	R266S	266	Missense	distal	-5	no	3.457	3.453	EPSD	COSMIC	3.202	Down-regulation
STE_STE20_PAKB_PAK5_ST	Q9P286	PAK5	Q9P286	PAK5	S271	R267K	267	Missense	distal	-4	no	3.457	3.433	EPSD	COSMIC	3.202	Down-regulation
STE_STE20_PAKB_PAK5_ST	Q9P286	PAK5	Q9P286	PAK5	S573	D568N	568	Missense	distal	-5	no	8.032	8.039	PhosphoSitePlus	COSMIC	3.202	Up-regulation
STE_STE20_PAKB_PAK5_ST	Q9P286	PAK5	Q9P286	PAK5	S573	H566Y	566	Missense	distal	-7	no	8.032	8.016	PhosphoSitePlus	COSMIC	3.202	Down-regulation
STE_STE20_PAKB_PAK5_ST	Q9P286	PAK5	Q9P286	PAK5	S573	D579N	579	Missense	distal	6	no	8.032	8.004	PhosphoSitePlus	COSMIC	3.202	Down-regulation
STE_STE20_PAKB_PAK5_ST	Q9P286	PAK5	Q9P286	PAK5	S573	R567S	567	Missense	distal	-6	no	8.032	7.804	PhosphoSitePlus	COSMIC	3.202	Down-regulation
STE_STE20_PAKB_PAK5_ST	Q9P286	PAK5	Q9P286	PAK5	S573	I574M	574	Missense	proximal	1	no	8.032	8.002	PhosphoSitePlus	COSMIC	3.202	Down-regulation
STE_STE20_PAKB_PAK5_ST	Q9P286	PAK5	Q9P286	PAK5	S573	I569T	569	Missense	distal	-4	no	8.032	7.932	PhosphoSitePlus	COSMIC	3.202	Down-regulation
STE_STE20_PAKB_PAK5_ST	Q9P286	PAK5	Q9P286	PAK5	S573	I569M	569	Missense	distal	-4	no	8.032	7.964	PhosphoSitePlus	COSMIC	3.202	Down-regulation
STE_STE20_PAKB_PAK5_ST	Q9P286	PAK5	Q9P286	PAK5	S658	A651V	651	Missense	distal	-7	no	4.211	4.281	EPSD	COSMIC	3.202	Up-regulation
STE_STE20_PAKB_PAK5_ST	Q9P286	PAK5	Q9P286	PAK5	S658	R662T	662	Missense	distal	4	no	4.211	4.345	EPSD	COSMIC	3.202	Up-regulation
STE_STE20_PAKB_PAK5_ST	Q9P286	PAK5	Q9P286	PAK5	S658	R656W	656	Missense	proximal	-2	no	4.211	4.188	EPSD	COSMIC	3.202	Down-regulation
STE_STE20_PAKB_PAK5_ST	Q9P286	PAK5	Q9P286	PAK5	S658	R654S	654	Missense	distal	-4	no	4.211	4.413	EPSD	COSMIC	3.202	Up-regulation
STE_STE20_PAKB_PAK5_ST	Q9P286	PAK5	Q9P286	PAK5	S658	A651S	651	Missense	distal	-7	no	4.211	3.955	EPSD	COSMIC	3.202	Down-regulation
STE_STE20_PAKB_PAK5_ST	Q9P286	PAK5	Q9P286	PAK5	S658	M652I	652	Missense	distal	-6	no	4.211	4.198	EPSD	COSMIC	3.202	Down-regulation
STE_STE20_PAKB_PAK5_ST	Q9P286	PAK5	Q9P286	PAK5	S658	R656G	656	Missense	proximal	-2	no	4.211	4.184	EPSD	COSMIC	3.202	Down-regulation
STE_STE20_PAKB_PAK5_ST	Q9P286	PAK5	Q9P286	PAK5	S658	V663A	663	Missense	distal	5	no	4.211	4.222	EPSD	COSMIC	3.202	Up-regulation
STE_STE20_PAKB_PAK5_ST	Q9P286	PAK5	Q9P286	PAK5	S658	R656Q	656	Missense	proximal	-2	no	4.211	4.162	EPSD	COSMIC	3.202	Down-regulation
STE_STE20_PAKB_PAK5_ST	P15923	TCF3	Q9P286	PAK5	S39	S39F	39	Missense	central	0	yes	8.243	0.000	PhosphoSitePlus	COSMIC	3.202	Loss
STE_STE20_PAKB_PAK5_ST	P15923	TCF3	Q9P286	PAK5	S39	A43V	43	Missense	distal	4	no	8.243	8.368	PhosphoSitePlus	COSMIC	3.202	Up-regulation
STE_STE20_PAKB_PAK5_ST	P15923	TCF3	Q9P286	PAK5	S39	G35D	35	Missense	distal	-4	no	8.243	8.135	PhosphoSitePlus	COSMIC	3.202	Down-regulation
STE_STE20_PAKB_PAK5_ST	P15923	TCF3	Q9P286	PAK5	S55	G62S	62	Missense	distal	7	no	4.552	4.293	EPSD	COSMIC	3.202	Down-regulation
STE_STE20_PAKB_PAK5_ST	P15923	TCF3	Q9P286	PAK5	S55	R53W	53	Missense	proximal	-2	no	4.552	4.528	EPSD	COSMIC	3.202	Down-regulation
STE_STE20_PAKB_PAK5_ST	P15923	TCF3	Q9P286	PAK5	S55	S58F	58	Missense	distal	3	no	4.552	4.472	EPSD	COSMIC	3.202	Down-regulation
STE_STE20_PAKB_PAK5_ST	P15923	TCF3	Q9P286	PAK5	S110	G112R	112	Missense	proximal	2	no	4.236	4.191	EPSD	COSMIC;GDSC;CCLE	3.202	Down-regulation
STE_STE20_PAKB_PAK5_ST	P15923	TCF3	Q9P286	PAK5	S110	V117M	117	Missense	distal	7	no	4.236	4.114	EPSD	COSMIC	3.202	Down-regulation
STE_STE20_PAKB_PAK5_ST	P15923	TCF3	Q9P286	PAK5	S110	E104K	104	Missense	distal	-6	no	4.236	4.161	EPSD	COSMIC	3.202	Down-regulation
STE_STE20_PAKB_PAK5_ST	P15923	TCF3	Q9P286	PAK5	S110	R105W	105	Missense	distal	-5	no	4.236	4.237	EPSD	COSMIC;GDSC;CCLE	3.202	Up-regulation
STE_STE20_PAKB_PAK5_ST	P15923	TCF3	Q9P286	PAK5	S110	G103S	103	Missense	distal	-7	no	4.236	4.092	EPSD	COSMIC	3.202	Down-regulation
STE_STE20_PAKB_PAK5_ST	P15923	TCF3	Q9P286	PAK5	S157	A161V	161	Missense	distal	4	no	3.421	3.545	EPSD	COSMIC	3.202	Up-regulation
STE_STE20_PAKB_PAK5_ST	P15923	TCF3	Q9P286	PAK5	S157	Y153C	153	Missense	distal	-4	no	3.421	3.466	EPSD	COSMIC	3.202	Up-regulation
STE_STE20_PAKB_PAK5_ST	P15923	TCF3	Q9P286	PAK5	S157	G155S	155	Missense	proximal	-2	no	3.421	3.416	EPSD	COSMIC	3.202	Down-regulation
STE_STE20_PAKB_PAK5_ST	P15923	TCF3	Q9P286	PAK5	S157	P151L	151	Missense	distal	-6	no	3.421	3.361	EPSD	COSMIC	3.202	Down-regulation
STE_STE20_PAKB_PAK5_ST	P15923	TCF3	Q9P286	PAK5	S157	A161T	161	Missense	distal	4	no	3.421	3.543	EPSD	COSMIC	3.202	Up-regulation
STE_STE20_PAKB_PAK5_ST	P15923	TCF3	Q9P286	PAK5	T198	A203T	203	Missense	distal	5	no	4.908	4.895	EPSD	COSMIC	3.202	Down-regulation
STE_STE20_PAKB_PAK5_ST	P15923	TCF3	Q9P286	PAK5	T198	A197T	197	Missense	proximal	-1	no	4.908	4.832	EPSD	COSMIC	3.202	Down-regulation
STE_STE20_PAKB_PAK5_ST	P15923	TCF3	Q9P286	PAK5	S306	G313V	313	Missense	distal	7	no	4.206	4.341	EPSD	COSMIC	3.202	Up-regulation
STE_STE20_PAKB_PAK5_ST	P15923	TCF3	Q9P286	PAK5	S306	G313R	313	Missense	distal	7	no	4.206	4.165	EPSD	COSMIC	3.202	Down-regulation
STE_STE20_PAKB_PAK5_ST	P15923	TCF3	Q9P286	PAK5	S338	G333D	333	Missense	distal	-5	no	3.430	3.423	EPSD	COSMIC	3.202	Down-regulation
STE_STE20_PAKB_PAK5_ST	P15923	TCF3	Q9P286	PAK5	S338	L332F	332	Missense	distal	-6	no	3.430	3.716	EPSD	COSMIC	3.202	Up-regulation
STE_STE20_PAKB_PAK5_ST	P15923	TCF3	Q9P286	PAK5	S350	S346N	346	Missense	distal	-4	no	3.461	3.291	EPSD	COSMIC	3.202	Down-regulation
STE_STE20_PAKB_PAK5_ST	P15923	TCF3	Q9P286	PAK5	S352	S346N	346	Missense	distal	-6	no	3.389	3.812	EPSD	COSMIC	3.202	Up-regulation
STE_STE20_PAKB_PAK5_ST	P15923	TCF3	Q9P286	PAK5	S352	P353L	353	Missense	proximal	1	no	3.389	3.324	EPSD	COSMIC;CCLE	3.202	Down-regulation
STE_STE20_PAKB_PAK5_ST	P15923	TCF3	Q9P286	PAK5	S367	R371Q	371	Missense	distal	4	no	3.908	3.931	EPSD	COSMIC	3.202	Up-regulation
STE_STE20_PAKB_PAK5_ST	P15923	TCF3	Q9P286	PAK5	S367	G373R	373	Missense	distal	6	no	3.908	3.963	EPSD	COSMIC	3.202	Up-regulation
STE_STE20_PAKB_PAK5_ST	P15923	TCF3	Q9P286	PAK5	S367	T366M	366	Missense	proximal	-1	no	3.908	3.812	EPSD	COSMIC	3.202	Down-regulation
STE_STE20_PAKB_PAK5_ST	P15923	TCF3	Q9P286	PAK5	S367	G362D	362	Missense	distal	-5	no	3.908	3.900	EPSD	COSMIC	3.202	Down-regulation
CAMK_CASK_CASK_ST	O14936	CASK	O14936	CASK	S51	F48L	48	Missense	distal	-3	no	3.339	3.081	EPSD	COSMIC	2.569	Down-regulation
CAMK_CASK_CASK_ST	O14936	CASK	O14936	CASK	S151	P157S	157	Missense	distal	6	no	7.373	7.605	PhosphoSitePlus;EPSD	COSMIC;GDSC;CCLE	2.569	Up-regulation
CAMK_CASK_CASK_ST	O14936	CASK	O14936	CASK	S151	P157L	157	Missense	distal	6	no	7.373	7.305	PhosphoSitePlus;EPSD	COSMIC	2.569	Down-regulation
CAMK_CASK_CASK_ST	O14936	CASK	O14936	CASK	S155	P157S	157	Missense	proximal	2	no	7.115	7.201	EPSD;PhosphoSitePlus	COSMIC;GDSC;CCLE	2.569	Up-regulation
CAMK_CASK_CASK_ST	O14936	CASK	O14936	CASK	S155	P157L	157	Missense	proximal	2	no	7.115	7.105	EPSD;PhosphoSitePlus	COSMIC	2.569	Down-regulation
CAMK_CASK_CASK_ST	O14936	CASK	O14936	CASK	S313	F317L	317	Missense	distal	4	no	2.590	2.335	EPSD	COSMIC	2.569	Loss
CAMK_CASK_CASK_ST	O14936	CASK	O14936	CASK	S394	D388E	388	Missense	distal	-6	no	2.904	2.889	EPSD	COSMIC	2.569	Down-regulation
CAMK_CASK_CASK_ST	O14936	CASK	O14936	CASK	S465	P462S	462	Missense	distal	-3	no	1.998	2.721	EPSD	COSMIC	2.569	Gain
CAMK_CASK_CASK_ST	O14936	CASK	O14936	CASK	S562	I563S	563	Missense	proximal	1	no	3.665	3.874	EPSD	COSMIC	2.569	Up-regulation
CAMK_CASK_CASK_ST	O14936	CASK	O14936	CASK	S562	P569L	569	Missense	distal	7	no	3.665	3.685	EPSD	COSMIC	2.569	Up-regulation
CAMK_CASK_CASK_ST	O14936	CASK	O14936	CASK	S596	S596L	596	Missense	central	0	yes	2.754	0.000	EPSD	COSMIC	2.569	Loss
CAMK_CASK_CASK_ST	O14936	CASK	O14936	CASK	S596	S600P	600	Missense	distal	4	no	2.754	1.783	EPSD	COSMIC	2.569	Loss
CAMK_CASK_CASK_ST	O14936	CASK	O14936	CASK	S596	S589L	589	Missense	distal	-7	no	2.754	2.813	EPSD	COSMIC	2.569	Up-regulation
CAMK_CASK_CASK_ST	O14936	CASK	O14936	CASK	S596	S600L	600	Missense	distal	4	no	2.754	1.561	EPSD	COSMIC	2.569	Loss
CAMK_CASK_CASK_ST	O14936	CASK	O14936	CASK	S602	S596L	596	Missense	distal	-6	no	3.566	3.723	EPSD	COSMIC	2.569	Up-regulation
CAMK_CASK_CASK_ST	O14936	CASK	O14936	CASK	S602	P605L	605	Missense	distal	3	no	3.566	3.552	EPSD	COSMIC	2.569	Down-regulation
CAMK_CASK_CASK_ST	O14936	CASK	O14936	CASK	S602	S600P	600	Missense	proximal	-2	no	3.566	3.600	EPSD	COSMIC	2.569	Up-regulation
CAMK_CASK_CASK_ST	O14936	CASK	O14936	CASK	S602	S600L	600	Missense	proximal	-2	no	3.566	3.593	EPSD	COSMIC	2.569	Up-regulation
CAMK_CASK_CASK_ST	O14936	CASK	O14936	CASK	S602	S606P	606	Missense	distal	4	no	3.566	2.595	EPSD	COSMIC	2.569	Down-regulation
CAMK_CASK_CASK_ST	O14936	CASK	O14936	CASK	S650	Q647K	647	Missense	distal	-3	no	2.161	3.161	EPSD	COSMIC	2.569	Gain
TK_FGFR_FGFR3_Y	P35222	CTNNB1	P22607	FGFR3	Y30	Y30C	30	Missense	central	0	yes	0.000	0.000	EPSD	COSMIC	0.000	Loss
TK_FGFR_FGFR3_Y	P35222	CTNNB1	P22607	FGFR3	Y30	Y30S	30	Missense	central	0	yes	0.000	0.000	EPSD	COSMIC	0.000	Loss
TK_FGFR_FGFR3_Y	P35222	CTNNB1	P22607	FGFR3	Y86	Y86H	86	Missense	central	0	yes	0.000	0.000	EPSD	COSMIC	0.000	Loss
TK_FGFR_FGFR3_Y	P35222	CTNNB1	P22607	FGFR3	Y716	Y716C	716	Missense	central	0	yes	0.000	0.000	EPSD	COSMIC	0.000	Loss
TK_FGFR_FGFR3_Y	P35222	CTNNB1	P22607	FGFR3	Y724	Y724S	724	Missense	central	0	yes	0.000	0.000	EPSD	COSMIC	0.000	Loss
TK_FGFR_FGFR3_Y	P35222	CTNNB1	P22607	FGFR3	Y724	Y724C	724	Missense	central	0	yes	0.000	0.000	EPSD	COSMIC	0.000	Loss
TK_FGFR_FGFR3_Y	P51812	RPS6KA3	P22607	FGFR3	Y234	Y234D	234	Missense	central	0	yes	0.000	0.000	EPSD	COSMIC	0.000	Loss
TK_FGFR_FGFR3_Y	P51812	RPS6KA3	P22607	FGFR3	Y483	Y483C	483	Missense	central	0	yes	0.000	0.000	EPSD	COSMIC	0.000	Loss
TK_FGFR_FGFR3_Y	P60484	PTEN	P22607	FGFR3	Y27	Y27H	27	Missense	central	0	yes	0.000	0.000	EPSD	COSMIC	0.000	Loss
TK_FGFR_FGFR3_Y	P60484	PTEN	P22607	FGFR3	Y27	Y27S	27	Missense	central	0	yes	0.000	0.000	EPSD	COSMIC	0.000	Loss
TK_FGFR_FGFR3_Y	P60484	PTEN	P22607	FGFR3	Y46	Y46C	46	Missense	central	0	yes	0.000	0.000	EPSD	COSMIC;GDSC;CCLE	0.000	Loss
TK_FGFR_FGFR3_Y	P60484	PTEN	P22607	FGFR3	Y68	Y68D	68	Missense	central	0	yes	0.000	0.000	EPSD	COSMIC	0.000	Loss
TK_FGFR_FGFR3_Y	P60484	PTEN	P22607	FGFR3	Y155	Y155H	155	Missense	central	0	yes	0.000	0.000	EPSD	COSMIC	0.000	Loss
TK_FGFR_FGFR3_Y	P60484	PTEN	P22607	FGFR3	Y155	Y155N	155	Missense	central	0	yes	0.000	0.000	EPSD	COSMIC	0.000	Loss
TK_FGFR_FGFR3_Y	P60484	PTEN	P22607	FGFR3	Y155	Y155S	155	Missense	central	0	yes	0.000	0.000	EPSD	COSMIC	0.000	Loss
TK_FGFR_FGFR3_Y	P60484	PTEN	P22607	FGFR3	Y174	Y174D	174	Missense	central	0	yes	0.000	0.000	EPSD	COSMIC	0.000	Loss
TK_FGFR_FGFR3_Y	P60484	PTEN	P22607	FGFR3	Y174	Y174N	174	Missense	central	0	yes	0.000	0.000	EPSD	COSMIC	0.000	Loss
TK_FGFR_FGFR3_Y	P60484	PTEN	P22607	FGFR3	Y174	Y174C	174	Missense	central	0	yes	0.000	0.000	EPSD	COSMIC	0.000	Loss
TK_FGFR_FGFR3_Y	P60484	PTEN	P22607	FGFR3	Y174	Y174H	174	Missense	central	0	yes	0.000	0.000	EPSD	COSMIC	0.000	Loss
TK_FGFR_FGFR3_Y	P60484	PTEN	P22607	FGFR3	Y176	Y176F	176	Missense	central	0	yes	0.000	0.000	EPSD	COSMIC	0.000	Loss
TK_FGFR_FGFR3_Y	P60484	PTEN	P22607	FGFR3	Y176	Y176C	176	Missense	central	0	yes	0.000	0.000	EPSD	COSMIC	0.000	Loss
TK_FGFR_FGFR3_Y	P60484	PTEN	P22607	FGFR3	Y177	Y177H	177	Missense	central	0	yes	0.000	0.000	EPSD	COSMIC	0.000	Loss
TK_FGFR_FGFR3_Y	P60484	PTEN	P22607	FGFR3	Y178	Y178H	178	Missense	central	0	yes	0.000	0.000	EPSD	COSMIC	0.000	Loss
TK_FGFR_FGFR3_Y	P60484	PTEN	P22607	FGFR3	Y178	Y178D	178	Missense	central	0	yes	0.000	0.000	EPSD	COSMIC	0.000	Loss
TK_FGFR_FGFR3_Y	P60484	PTEN	P22607	FGFR3	Y178	Y178F	178	Missense	central	0	yes	0.000	0.000	EPSD	COSMIC	0.000	Loss
TK_FGFR_FGFR3_Y	P60484	PTEN	P22607	FGFR3	Y178	Y178N	178	Missense	central	0	yes	0.000	0.000	EPSD	COSMIC	0.000	Loss
TK_FGFR_FGFR3_Y	P60484	PTEN	P22607	FGFR3	Y315	Y315H	315	Missense	central	0	yes	0.000	0.000	EPSD	COSMIC	0.000	Loss
TK_FGFR_FGFR3_Y	P60484	PTEN	P22607	FGFR3	Y336	Y336C	336	Missense	central	0	yes	0.000	0.000	EPSD	COSMIC	0.000	Loss
TK_FGFR_FGFR3_Y	P60484	PTEN	P22607	FGFR3	Y336	Y336F	336	Missense	central	0	yes	0.000	0.000	EPSD	COSMIC	0.000	Loss
TK_FGFR_FGFR3_Y	P42224	STAT1	P22607	FGFR3	Y668	Y668C	668	Missense	central	0	yes	0.000	0.000	EPSD	COSMIC	0.000	Loss
STE_STE7_MEK3_MAP2K6_ST	P53778	MAPK12	P52564	MAP2K6	T183	T188A	188	Missense	distal	5	no	9.659	9.645	EPSD;PhosphoSitePlus	COSMIC	1.858	Down-regulation
STE_STE7_MEK3_MAP2K6_ST	P53778	MAPK12	P52564	MAP2K6	T183	W190L	190	Missense	distal	7	no	9.659	9.612	EPSD;PhosphoSitePlus	COSMIC	1.858	Down-regulation
STE_STE7_MEK3_MAP2K6_ST	P53778	MAPK12	P52564	MAP2K6	T183	G184W	184	Missense	proximal	1	no	9.659	9.755	EPSD;PhosphoSitePlus	COSMIC	1.858	Up-regulation
STE_STE7_MEK3_MAP2K6_ST	P53778	MAPK12	P52564	MAP2K6	T183	R176M	176	Missense	distal	-7	no	9.659	9.650	EPSD;PhosphoSitePlus	COSMIC	1.858	Down-regulation
STE_STE7_MEK3_MAP2K6_ST	O15264	MAPK13	P52564	MAP2K6	T180	V183M	183	Missense	distal	3	no	9.851	10.068	PhosphoSitePlus;EPSD	COSMIC;GDSC;CCLE	1.858	Up-regulation
STE_STE7_MEK3_MAP2K6_ST	O15264	MAPK13	P52564	MAP2K6	T180	R186S	186	Missense	distal	6	no	9.851	9.822	PhosphoSitePlus;EPSD	COSMIC	1.858	Down-regulation
STE_STE7_MEK3_MAP2K6_ST	P52564	MAP2K6	P52564	MAP2K6	S35	A37T	37	Missense	proximal	2	no	2.336	1.080	EPSD	COSMIC	1.858	Loss
STE_STE7_MEK3_MAP2K6_ST	P52564	MAP2K6	P52564	MAP2K6	S35	T28I	28	Missense	distal	-7	no	2.336	2.456	EPSD	COSMIC;GDSC	1.858	Up-regulation
STE_STE7_MEK3_MAP2K6_ST	P52564	MAP2K6	P52564	MAP2K6	S35	P29S	29	Missense	distal	-6	no	2.336	2.317	EPSD	COSMIC	1.858	Down-regulation
STE_STE7_MEK3_MAP2K6_ST	P52564	MAP2K6	P52564	MAP2K6	S207	D213Y	213	Missense	distal	6	no	8.152	8.082	PhosphoSitePlus;EPSD	COSMIC	1.858	Down-regulation
STE_STE7_MEK3_MAP2K6_ST	P52564	MAP2K6	P52564	MAP2K6	T211	D213Y	213	Missense	proximal	2	no	1.273	4.532	EPSD	COSMIC	1.858	Gain
STE_STE7_MEK3_MAP2K6_ST	Q9ULV5	HSF4	P52564	MAP2K6	T471	T475I	475	Missense	distal	4	no	8.305	8.343	PhosphoSitePlus	COSMIC	1.858	Up-regulation
STE_STE7_MEK3_MAP2K6_ST	Q9ULV5	HSF4	P52564	MAP2K6	T471	E477K	477	Missense	distal	6	no	8.305	8.345	PhosphoSitePlus	COSMIC	1.858	Up-regulation
STE_STE7_MEK3_MAP2K6_ST	Q16539	MAPK14	P52564	MAP2K6	T7	E4Q	4	Missense	distal	-3	no	3.567	3.491	EPSD	COSMIC	1.858	Down-regulation
STE_STE7_MEK3_MAP2K6_ST	Q16539	MAPK14	P52564	MAP2K6	T180	T185I	185	Missense	distal	5	no	9.830	9.831	PhosphoSitePlus;EPSD	COSMIC	1.858	Up-regulation
STE_STE7_MEK3_MAP2K6_ST	Q9NQU5	PAK6	P52564	MAP2K6	S165	R167Q	167	Missense	proximal	2	no	1.651	1.888	EPSD	COSMIC	1.858	Gain
STE_STE7_MEK3_MAP2K6_ST	Q9NQU5	PAK6	P52564	MAP2K6	T326	S319C	319	Missense	distal	-7	no	3.364	3.232	EPSD	COSMIC	1.858	Down-regulation
STE_STE7_MEK3_MAP2K6_ST	Q9NQU5	PAK6	P52564	MAP2K6	T371	L364V	364	Missense	distal	-7	no	2.056	1.995	EPSD	COSMIC	1.858	Down-regulation
STE_STE7_MEK3_MAP2K6_ST	Q9NQU5	PAK6	P52564	MAP2K6	T371	V372G	372	Missense	proximal	1	no	2.056	1.935	EPSD	COSMIC	1.858	Down-regulation
TK_Csk_MATK_Y	P78324	SIRPA	P42679	MATK	Y453	S459N	459	Missense	distal	6	no	5.088	5.085	PhosphoSitePlus;EPSD	COSMIC	1.382	Down-regulation
TK_Csk_MATK_Y	P78324	SIRPA	P42679	MATK	Y453	S459R	459	Missense	distal	6	no	5.088	5.095	PhosphoSitePlus;EPSD	COSMIC	1.382	Up-regulation
TK_Csk_MATK_Y	P78324	SIRPA	P42679	MATK	Y453	S459T	459	Missense	distal	6	no	5.088	5.160	PhosphoSitePlus;EPSD	COSMIC	1.382	Up-regulation
TK_Csk_MATK_Y	P07948	LYN	P42679	MATK	Y508	Y508H	508	Missense	central	0	yes	4.938	0.000	PhosphoSitePlus	COSMIC	1.382	Loss
TK_Csk_MATK_Y	P07948	LYN	P42679	MATK	Y508	Y501C	501	Missense	distal	-7	no	4.938	4.928	PhosphoSitePlus	COSMIC	1.382	Down-regulation
TK_Csk_MATK_Y	P07948	LYN	P42679	MATK	Y508	G506E	506	Missense	proximal	-2	no	4.938	4.971	PhosphoSitePlus	COSMIC	1.382	Up-regulation
CK1_VRK_VRK2_ST	P38432	COIL	Q86Y07	VRK2	S184	A180V	180	Missense	distal	-4	no	100.519	101.450	PhosphoSitePlus	COSMIC;GDSC	34.967	Up-regulation
CK1_VRK_VRK2_ST	P38432	COIL	Q86Y07	VRK2	S184	A180S	180	Missense	distal	-4	no	100.519	102.113	PhosphoSitePlus	COSMIC	34.967	Up-regulation
CK1_VRK_VRK2_ST	P38432	COIL	Q86Y07	VRK2	S217	N213S	213	Missense	distal	-4	no	36.934	37.586	EPSD	COSMIC	34.967	Up-regulation
CK1_VRK_VRK2_ST	P38432	COIL	Q86Y07	VRK2	S217	G221S	221	Missense	distal	4	no	36.934	38.096	EPSD	COSMIC	34.967	Up-regulation
CK1_VRK_VRK2_ST	P38432	COIL	Q86Y07	VRK2	S218	N213S	213	Missense	distal	-5	no	45.794	45.966	EPSD	COSMIC	34.967	Up-regulation
CK1_VRK_VRK2_ST	P38432	COIL	Q86Y07	VRK2	S218	G221S	221	Missense	distal	3	no	45.794	45.170	EPSD	COSMIC	34.967	Down-regulation
CK1_VRK_VRK2_ST	P38432	COIL	Q86Y07	VRK2	S235	A230V	230	Missense	distal	-5	no	34.699	36.128	EPSD	COSMIC	34.967	Gain
CK1_VRK_VRK2_ST	P38432	COIL	Q86Y07	VRK2	S235	V236L	236	Missense	proximal	1	no	34.699	36.262	EPSD	COSMIC;CCLE	34.967	Gain
CK1_VRK_VRK2_ST	P38432	COIL	Q86Y07	VRK2	S235	C239S	239	Missense	distal	4	no	34.699	35.206	EPSD	COSMIC	34.967	Gain
CK1_VRK_VRK2_ST	P38432	COIL	Q86Y07	VRK2	S237	A230V	230	Missense	distal	-7	no	35.455	35.242	EPSD	COSMIC	34.967	Down-regulation
CK1_VRK_VRK2_ST	P38432	COIL	Q86Y07	VRK2	S237	V236L	236	Missense	proximal	-1	no	35.455	38.746	EPSD	COSMIC;CCLE	34.967	Up-regulation
CK1_VRK_VRK2_ST	P38432	COIL	Q86Y07	VRK2	S237	C239S	239	Missense	proximal	2	no	35.455	41.789	EPSD	COSMIC	34.967	Up-regulation
CK1_VRK_VRK2_ST	P38432	COIL	Q86Y07	VRK2	S256	D254H	254	Missense	proximal	-2	no	38.945	39.138	EPSD	COSMIC	34.967	Up-regulation
CK1_VRK_VRK2_ST	Q9UHP3	USP25	Q86Y07	VRK2	S725	A732S	732	Missense	distal	7	no	42.104	42.511	EPSD	COSMIC	34.967	Up-regulation
CK1_VRK_VRK2_ST	Q9UHP3	USP25	Q86Y07	VRK2	S725	A718V	718	Missense	distal	-7	no	42.104	41.890	EPSD	COSMIC;GDSC;CCLE	34.967	Down-regulation
CK1_VRK_VRK2_ST	Q9UHP3	USP25	Q86Y07	VRK2	T727	A732S	732	Missense	distal	5	no	101.630	102.603	EPSD;PhosphoSitePlus	COSMIC	34.967	Up-regulation
CK1_VRK_VRK2_ST	Q9UHP3	USP25	Q86Y07	VRK2	T730	A732S	732	Missense	proximal	2	no	32.799	39.591	EPSD	COSMIC	34.967	Gain
CK1_VRK_VRK2_ST	O75531	BANF1	Q86Y07	VRK2	T2	S4F	4	Missense	proximal	2	no	63.938	57.296	PhosphoSitePlus;EPSD	COSMIC	34.967	Down-regulation
CK1_VRK_VRK2_ST	O75531	BANF1	Q86Y07	VRK2	T3	S4F	4	Missense	proximal	1	no	70.420	71.294	EPSD;PhosphoSitePlus	COSMIC	34.967	Up-regulation
CK1_VRK_VRK2_ST	O75531	BANF1	Q86Y07	VRK2	S4	S4F	4	Missense	central	0	yes	62.339	0.000	EPSD;PhosphoSitePlus	COSMIC	34.967	Loss
CK1_VRK_VRK2_ST	Q96EV8	DTNBP1	Q86Y07	VRK2	T115	E112D	112	Missense	distal	-3	no	45.631	45.783	EPSD	COSMIC	34.967	Up-regulation
CK1_VRK_VRK2_ST	Q96EV8	DTNBP1	Q86Y07	VRK2	T115	E112Q	112	Missense	distal	-3	no	45.631	45.809	EPSD	COSMIC	34.967	Up-regulation
CK1_VRK_VRK2_ST	Q96EV8	DTNBP1	Q86Y07	VRK2	T119	E112D	112	Missense	distal	-7	no	54.713	53.662	EPSD	COSMIC	34.967	Down-regulation
CK1_VRK_VRK2_ST	Q96EV8	DTNBP1	Q86Y07	VRK2	T119	E112Q	112	Missense	distal	-7	no	54.713	57.328	EPSD	COSMIC	34.967	Up-regulation
CK1_VRK_VRK2_ST	Q96EV8	DTNBP1	Q86Y07	VRK2	T119	E126A	126	Missense	distal	7	no	54.713	54.960	EPSD	COSMIC	34.967	Up-regulation
AGC_DMPK_ROCK_ROCK1_ST	Q14160	SCRIB	Q13464	ROCK1	S35	I31T	31	Missense	distal	-4	no	33.012	33.095	EPSD	COSMIC	31.796	Up-regulation
AGC_DMPK_ROCK_ROCK1_ST	Q14160	SCRIB	Q13464	ROCK1	S35	P28Q	28	Missense	distal	-7	no	33.012	33.182	EPSD	COSMIC	31.796	Up-regulation
AGC_DMPK_ROCK_ROCK1_ST	Q14160	SCRIB	Q13464	ROCK1	S432	Q430R	430	Missense	proximal	-2	no	19.490	32.660	EPSD	COSMIC	31.796	Gain
AGC_DMPK_ROCK_ROCK1_ST	Q14160	SCRIB	Q13464	ROCK1	T475	E480K	480	Missense	distal	5	no	48.836	48.131	EPSD	COSMIC	31.796	Down-regulation
AGC_DMPK_ROCK_ROCK1_ST	Q14160	SCRIB	Q13464	ROCK1	T475	Q471H	471	Missense	distal	-4	no	48.836	47.402	EPSD	COSMIC	31.796	Down-regulation
AGC_DMPK_ROCK_ROCK1_ST	Q14160	SCRIB	Q13464	ROCK1	S493	G490R	490	Missense	distal	-3	no	33.216	43.406	EPSD	COSMIC	31.796	Up-regulation
AGC_DMPK_ROCK_ROCK1_ST	Q14160	SCRIB	Q13464	ROCK1	S493	R491W	491	Missense	proximal	-2	no	33.216	32.131	EPSD	COSMIC	31.796	Down-regulation
AGC_DMPK_ROCK_ROCK1_ST	Q14160	SCRIB	Q13464	ROCK1	T607	R604L	604	Missense	distal	-3	no	46.730	35.258	EPSD	COSMIC	31.796	Down-regulation
AGC_DMPK_ROCK_ROCK1_ST	Q14160	SCRIB	Q13464	ROCK1	T607	R604C	604	Missense	distal	-3	no	46.730	21.446	EPSD	COSMIC;CCLE	31.796	Loss
AGC_DMPK_ROCK_ROCK1_ST	Q14160	SCRIB	Q13464	ROCK1	T908	A906T	906	Missense	proximal	-2	no	29.651	33.304	EPSD	COSMIC	31.796	Gain
AGC_DMPK_ROCK_ROCK1_ST	Q14160	SCRIB	Q13464	ROCK1	T1130	G1133D	1133	Missense	distal	3	no	32.335	32.162	EPSD	COSMIC	31.796	Down-regulation
AGC_DMPK_ROCK_ROCK1_ST	Q14160	SCRIB	Q13464	ROCK1	S1378	E1371D	1371	Missense	distal	-7	no	39.728	39.703	EPSD;PhosphoSitePlus	COSMIC	31.796	Down-regulation
AGC_DMPK_ROCK_ROCK1_ST	Q14160	SCRIB	Q13464	ROCK1	S1508	L1514I	1514	Missense	distal	6	no	38.412	38.410	PhosphoSitePlus;EPSD	COSMIC	31.796	Down-regulation
AGC_DMPK_ROCK_ROCK1_ST	Q14160	SCRIB	Q13464	ROCK1	S1508	D1512G	1512	Missense	distal	4	no	38.412	39.561	PhosphoSitePlus;EPSD	COSMIC	31.796	Up-regulation
AGC_DMPK_ROCK_ROCK1_ST	P35241	RDX	Q13464	ROCK1	T66	E73K	73	Missense	distal	7	no	36.036	35.471	EPSD	COSMIC	31.796	Down-regulation
AGC_DMPK_ROCK_ROCK1_ST	P35241	RDX	Q13464	ROCK1	T564	G571C	571	Missense	distal	7	no	33.014	33.033	PhosphoSitePlus	COSMIC	31.796	Up-regulation
AGC_DMPK_ROCK_ROCK1_ST	P35241	RDX	Q13464	ROCK1	T564	R559C	559	Missense	distal	-5	no	33.014	27.380	PhosphoSitePlus	COSMIC	31.796	Loss
AGC_DMPK_ROCK_ROCK1_ST	P61587	RND3	Q13464	ROCK1	S7	L10V	10	Missense	distal	3	no	40.635	40.751	EPSD;PhosphoSitePlus	COSMIC	31.796	Up-regulation
AGC_DMPK_ROCK_ROCK1_ST	P61587	RND3	Q13464	ROCK1	S210	A213P	213	Missense	distal	3	no	34.644	34.661	EPSD	COSMIC	31.796	Up-regulation
AGC_DMPK_ROCK_ROCK1_ST	P61587	RND3	Q13464	ROCK1	S210	N204S	204	Missense	distal	-6	no	34.644	35.790	EPSD	COSMIC	31.796	Up-regulation
AGC_DMPK_ROCK_ROCK1_ST	P61587	RND3	Q13464	ROCK1	S210	A213V	213	Missense	distal	3	no	34.644	34.645	EPSD	COSMIC	31.796	Up-regulation
AGC_DMPK_ROCK_ROCK1_ST	P61587	RND3	Q13464	ROCK1	S210	R207W	207	Missense	distal	-3	no	34.644	25.482	EPSD	COSMIC	31.796	Loss
AGC_DMPK_ROCK_ROCK1_ST	P61587	RND3	Q13464	ROCK1	S218	A213P	213	Missense	distal	-5	no	51.293	49.180	EPSD;PhosphoSitePlus	COSMIC	31.796	Down-regulation
AGC_DMPK_ROCK_ROCK1_ST	P61587	RND3	Q13464	ROCK1	S218	R223G	223	Missense	distal	5	no	51.293	51.698	EPSD;PhosphoSitePlus	COSMIC;CCLE	31.796	Up-regulation
AGC_DMPK_ROCK_ROCK1_ST	P61587	RND3	Q13464	ROCK1	S218	R223I	223	Missense	distal	5	no	51.293	52.053	EPSD;PhosphoSitePlus	COSMIC	31.796	Up-regulation
AGC_DMPK_ROCK_ROCK1_ST	P61587	RND3	Q13464	ROCK1	S218	A213V	213	Missense	distal	-5	no	51.293	48.482	EPSD;PhosphoSitePlus	COSMIC	31.796	Down-regulation
AGC_DMPK_ROCK_ROCK1_ST	P19634	SLC9A1	Q13464	ROCK1	S648	R645W	645	Missense	distal	-3	no	35.012	25.850	EPSD	COSMIC;GDSC;CCLE	31.796	Loss
AGC_DMPK_ROCK_ROCK1_ST	P19634	SLC9A1	Q13464	ROCK1	S648	R645L	645	Missense	distal	-3	no	35.012	23.540	EPSD	COSMIC	31.796	Loss
AGC_DMPK_ROCK_ROCK1_ST	P19634	SLC9A1	Q13464	ROCK1	T653	D657Y	657	Missense	distal	4	no	43.592	43.804	PhosphoSitePlus	COSMIC	31.796	Up-regulation
AGC_DMPK_ROCK_ROCK1_ST	Q9NRY4	ARHGAP35	Q13464	ROCK1	T136	E129D	129	Missense	distal	-7	no	37.806	37.781	EPSD	COSMIC;GDSC;CCLE	31.796	Down-regulation
AGC_DMPK_ROCK_ROCK1_ST	Q9NRY4	ARHGAP35	Q13464	ROCK1	S1010	D1008N	1008	Missense	proximal	-2	no	30.057	32.035	EPSD	COSMIC;CCLE	31.796	Gain
AGC_DMPK_ROCK_ROCK1_ST	Q9NRY4	ARHGAP35	Q13464	ROCK1	S1070	S1070F	1070	Missense	central	0	yes	50.544	0.000	EPSD	COSMIC	31.796	Loss
AGC_DMPK_ROCK_ROCK1_ST	Q9NRY4	ARHGAP35	Q13464	ROCK1	S1072	S1070F	1070	Missense	proximal	-2	no	39.561	41.115	EPSD	COSMIC	31.796	Up-regulation
AGC_DMPK_ROCK_ROCK1_ST	Q9NRY4	ARHGAP35	Q13464	ROCK1	S1074	S1070F	1070	Missense	distal	-4	no	33.640	31.614	EPSD	COSMIC	31.796	Loss
AGC_DMPK_ROCK_ROCK1_ST	Q9NRY4	ARHGAP35	Q13464	ROCK1	S1130	S1127Y	1127	Missense	distal	-3	no	30.308	35.482	EPSD	COSMIC	31.796	Gain
AGC_DMPK_ROCK_ROCK1_ST	Q9NRY4	ARHGAP35	Q13464	ROCK1	S1134	G1131R	1131	Missense	distal	-3	no	29.365	39.555	EPSD	COSMIC;GDSC;CCLE	31.796	Gain
AGC_DMPK_ROCK_ROCK1_ST	Q9NRY4	ARHGAP35	Q13464	ROCK1	S1150	V1149I	1149	Missense	proximal	-1	no	41.805	41.465	EPSD;PhosphoSitePlus	COSMIC	31.796	Down-regulation
AGC_DMPK_ROCK_ROCK1_ST	Q9NRY4	ARHGAP35	Q13464	ROCK1	S1170	A1169D	1169	Missense	proximal	-1	no	40.317	38.940	EPSD	COSMIC;GDSC;CCLE	31.796	Down-regulation
AGC_DMPK_ROCK_ROCK1_ST	Q9NRY4	ARHGAP35	Q13464	ROCK1	T1173	A1169D	1169	Missense	distal	-4	no	33.235	33.197	PhosphoSitePlus;EPSD	COSMIC;GDSC;CCLE	31.796	Down-regulation
AGC_DMPK_ROCK_ROCK1_ST	Q9NRY4	ARHGAP35	Q13464	ROCK1	S1174	A1169D	1169	Missense	distal	-5	no	37.594	36.706	EPSD;PhosphoSitePlus	COSMIC;GDSC;CCLE	31.796	Down-regulation
AGC_DMPK_ROCK_ROCK1_ST	Q9NRY4	ARHGAP35	Q13464	ROCK1	S1176	A1169D	1169	Missense	distal	-7	no	32.634	32.631	EPSD	COSMIC;GDSC;CCLE	31.796	Down-regulation
AGC_DMPK_ROCK_ROCK1_ST	Q9NRY4	ARHGAP35	Q13464	ROCK1	S1290	G1287R	1287	Missense	distal	-3	no	34.442	44.632	EPSD	COSMIC	31.796	Up-regulation
AGC_DMPK_ROCK_ROCK1_ST	Q9NRY4	ARHGAP35	Q13464	ROCK1	S1290	S1290Y	1290	Missense	central	0	yes	34.442	0.000	EPSD	COSMIC	31.796	Loss
AGC_DMPK_ROCK_ROCK1_ST	Q9Y613	FHOD1	Q13464	ROCK1	S357	E359K	359	Missense	proximal	2	no	38.076	41.746	EPSD	COSMIC	31.796	Up-regulation
AGC_DMPK_ROCK_ROCK1_ST	Q9Y613	FHOD1	Q13464	ROCK1	S367	G371R	371	Missense	distal	4	no	38.259	38.690	EPSD	COSMIC	31.796	Up-regulation
AGC_DMPK_ROCK_ROCK1_ST	Q9Y613	FHOD1	Q13464	ROCK1	S367	S367Y	367	Missense	central	0	yes	38.259	0.000	EPSD	COSMIC	31.796	Loss
AGC_DMPK_ROCK_ROCK1_ST	Q9Y613	FHOD1	Q13464	ROCK1	T1010	R1013H	1013	Missense	distal	3	no	32.912	32.816	EPSD	COSMIC	31.796	Down-regulation
AGC_DMPK_ROCK_ROCK1_ST	Q9Y613	FHOD1	Q13464	ROCK1	T1010	E1017K	1017	Missense	distal	7	no	32.912	32.348	EPSD	COSMIC	31.796	Down-regulation
AGC_DMPK_ROCK_ROCK1_ST	Q9Y613	FHOD1	Q13464	ROCK1	T1010	R1013C	1013	Missense	distal	3	no	32.912	32.719	EPSD	COSMIC	31.796	Down-regulation
AGC_DMPK_ROCK_ROCK1_ST	Q9Y613	FHOD1	Q13464	ROCK1	T1016	R1013H	1013	Missense	distal	-3	no	34.517	19.907	EPSD	COSMIC	31.796	Loss
AGC_DMPK_ROCK_ROCK1_ST	Q9Y613	FHOD1	Q13464	ROCK1	T1016	E1017K	1017	Missense	proximal	1	no	34.517	33.672	EPSD	COSMIC	31.796	Down-regulation
AGC_DMPK_ROCK_ROCK1_ST	Q9Y613	FHOD1	Q13464	ROCK1	T1016	R1013C	1013	Missense	distal	-3	no	34.517	9.233	EPSD	COSMIC	31.796	Loss
AGC_DMPK_ROCK_ROCK1_ST	Q9Y613	FHOD1	Q13464	ROCK1	T1016	E1019Q	1019	Missense	distal	3	no	34.517	34.598	EPSD	COSMIC	31.796	Up-regulation
AGC_DMPK_ROCK_ROCK1_ST	Q9Y613	FHOD1	Q13464	ROCK1	T1016	E1019D	1019	Missense	distal	3	no	34.517	34.549	EPSD	COSMIC	31.796	Up-regulation
AGC_DMPK_ROCK_ROCK1_ST	Q9Y613	FHOD1	Q13464	ROCK1	S1052	T1058I	1058	Missense	distal	6	no	37.714	37.561	EPSD	COSMIC	31.796	Down-regulation
AGC_DMPK_ROCK_ROCK1_ST	Q9Y613	FHOD1	Q13464	ROCK1	S1055	R1060G	1060	Missense	distal	5	no	34.981	35.385	EPSD	COSMIC	31.796	Up-regulation
AGC_DMPK_ROCK_ROCK1_ST	Q9Y613	FHOD1	Q13464	ROCK1	S1055	T1058I	1058	Missense	distal	3	no	34.981	34.801	EPSD	COSMIC	31.796	Down-regulation
AGC_DMPK_ROCK_ROCK1_ST	Q9Y613	FHOD1	Q13464	ROCK1	S1131	G1133S	1133	Missense	proximal	2	no	37.343	37.123	EPSD;PhosphoSitePlus	COSMIC	31.796	Down-regulation
AGC_DMPK_ROCK_ROCK1_ST	Q9Y613	FHOD1	Q13464	ROCK1	S1137	G1133S	1133	Missense	distal	-4	no	44.904	44.746	PhosphoSitePlus;EPSD	COSMIC	31.796	Down-regulation
AGC_DMPK_ROCK_ROCK1_ST	Q9Y613	FHOD1	Q13464	ROCK1	S1137	R1140K	1140	Missense	distal	3	no	44.904	44.931	PhosphoSitePlus;EPSD	COSMIC	31.796	Up-regulation
AGC_DMPK_ROCK_ROCK1_ST	Q9Y613	FHOD1	Q13464	ROCK1	T1141	R1140K	1140	Missense	proximal	-1	no	50.072	50.133	EPSD;PhosphoSitePlus	COSMIC	31.796	Up-regulation
AGC_DMPK_ROCK_ROCK1_ST	Q9Y613	FHOD1	Q13464	ROCK1	T1141	G1145V	1145	Missense	distal	4	no	50.072	48.800	EPSD;PhosphoSitePlus	COSMIC	31.796	Down-regulation
AGC_DMPK_ROCK_ROCK1_ST	Q8N264	ARHGAP24	Q13464	ROCK1	T97	D94H	94	Missense	distal	-3	no	39.339	33.507	EPSD	COSMIC	31.796	Down-regulation
AGC_DMPK_ROCK_ROCK1_ST	Q8N264	ARHGAP24	Q13464	ROCK1	T97	R95Q	95	Missense	proximal	-2	no	39.339	26.169	EPSD	COSMIC;GDSC	31.796	Loss
AGC_DMPK_ROCK_ROCK1_ST	Q8N264	ARHGAP24	Q13464	ROCK1	S108	D112N	112	Missense	distal	4	no	34.488	34.721	EPSD	COSMIC	31.796	Up-regulation
AGC_DMPK_ROCK_ROCK1_ST	Q8N264	ARHGAP24	Q13464	ROCK1	S391	G390V	390	Missense	proximal	-1	no	35.961	33.543	PhosphoSitePlus;EPSD	COSMIC	31.796	Down-regulation
AGC_DMPK_ROCK_ROCK1_ST	Q8N264	ARHGAP24	Q13464	ROCK1	S391	G390D	390	Missense	proximal	-1	no	35.961	32.773	PhosphoSitePlus;EPSD	COSMIC	31.796	Down-regulation
AGC_DMPK_ROCK_ROCK1_ST	Q8N264	ARHGAP24	Q13464	ROCK1	S437	T434S	434	Missense	distal	-3	no	33.437	30.379	EPSD;PhosphoSitePlus	COSMIC	31.796	Loss
AGC_DMPK_ROCK_ROCK1_ST	Q8N264	ARHGAP24	Q13464	ROCK1	S462	S463P	463	Missense	proximal	1	no	38.776	38.580	EPSD	COSMIC	31.796	Down-regulation
AGC_DMPK_ROCK_ROCK1_ST	Q8N264	ARHGAP24	Q13464	ROCK1	S462	R460K	460	Missense	proximal	-2	no	38.776	31.025	EPSD	COSMIC;GDSC;CCLE	31.796	Loss
AGC_DMPK_ROCK_ROCK1_ST	Q8N264	ARHGAP24	Q13464	ROCK1	S462	S463F	463	Missense	proximal	1	no	38.776	38.996	EPSD	COSMIC	31.796	Up-regulation
AGC_DMPK_ROCK_ROCK1_ST	Q8N264	ARHGAP24	Q13464	ROCK1	S463	S463P	463	Missense	central	0	yes	38.548	0.000	EPSD	COSMIC	31.796	Loss
AGC_DMPK_ROCK_ROCK1_ST	Q8N264	ARHGAP24	Q13464	ROCK1	S463	R460K	460	Missense	distal	-3	no	38.548	34.838	EPSD	COSMIC;GDSC;CCLE	31.796	Down-regulation
AGC_DMPK_ROCK_ROCK1_ST	Q8N264	ARHGAP24	Q13464	ROCK1	S463	S463F	463	Missense	central	0	yes	38.548	0.000	EPSD	COSMIC	31.796	Loss
AGC_DMPK_ROCK_ROCK1_ST	Q8N264	ARHGAP24	Q13464	ROCK1	S464	S463P	463	Missense	proximal	-1	no	40.351	38.332	EPSD	COSMIC	31.796	Down-regulation
AGC_DMPK_ROCK_ROCK1_ST	Q8N264	ARHGAP24	Q13464	ROCK1	S464	R460K	460	Missense	distal	-4	no	40.351	39.714	EPSD	COSMIC;GDSC;CCLE	31.796	Down-regulation
AGC_DMPK_ROCK_ROCK1_ST	Q8N264	ARHGAP24	Q13464	ROCK1	S464	K471R	471	Missense	distal	7	no	40.351	39.725	EPSD	COSMIC	31.796	Down-regulation
AGC_DMPK_ROCK_ROCK1_ST	Q8N264	ARHGAP24	Q13464	ROCK1	S464	S463F	463	Missense	proximal	-1	no	40.351	37.148	EPSD	COSMIC	31.796	Down-regulation
AGC_DMPK_ROCK_ROCK1_ST	Q8N264	ARHGAP24	Q13464	ROCK1	S530	H526Y	526	Missense	distal	-4	no	36.043	36.188	EPSD	COSMIC	31.796	Up-regulation
AGC_DMPK_ROCK_ROCK1_ST	Q8N264	ARHGAP24	Q13464	ROCK1	S611	D606V	606	Missense	distal	-5	no	31.857	29.934	EPSD	COSMIC	31.796	Loss
AGC_DMPK_ROCK_ROCK1_ST	Q8N264	ARHGAP24	Q13464	ROCK1	S611	Y607C	607	Missense	distal	-4	no	31.857	29.523	EPSD	COSMIC;GDSC;CCLE	31.796	Loss
AGC_DMPK_ROCK_ROCK1_ST	Q8N264	ARHGAP24	Q13464	ROCK1	S611	S609N	609	Missense	proximal	-2	no	31.857	34.568	EPSD	COSMIC	31.796	Up-regulation
AGC_DMPK_ROCK_ROCK1_ST	Q8N264	ARHGAP24	Q13464	ROCK1	T624	A623T	623	Missense	proximal	-1	no	38.769	39.820	EPSD	COSMIC	31.796	Up-regulation
AGC_DMPK_ROCK_ROCK1_ST	Q8N264	ARHGAP24	Q13464	ROCK1	S625	A623T	623	Missense	proximal	-2	no	38.369	42.023	EPSD	COSMIC	31.796	Up-regulation
AGC_DMPK_ROCK_ROCK1_ST	Q8N264	ARHGAP24	Q13464	ROCK1	S626	A623T	623	Missense	distal	-3	no	25.849	32.384	EPSD	COSMIC	31.796	Gain
AGC_DMPK_ROCK_ROCK1_ST	Q8N264	ARHGAP24	Q13464	ROCK1	S627	A623T	623	Missense	distal	-4	no	35.021	35.222	EPSD	COSMIC	31.796	Up-regulation
AGC_DMPK_ROCK_ROCK1_ST	P15311	EZR	Q13464	ROCK1	T332	V333M	333	Missense	proximal	1	no	33.836	33.743	EPSD	COSMIC;CCLE	31.796	Down-regulation
AGC_DMPK_ROCK_ROCK1_ST	P15311	EZR	Q13464	ROCK1	T332	V333L	333	Missense	proximal	1	no	33.836	34.054	EPSD	COSMIC	31.796	Up-regulation
AGC_DMPK_ROCK_ROCK1_ST	P15311	EZR	Q13464	ROCK1	T332	E338G	338	Missense	distal	6	no	33.836	33.816	EPSD	COSMIC	31.796	Down-regulation
AGC_DMPK_ROCK_ROCK1_ST	P15311	EZR	Q13464	ROCK1	S366	R363K	363	Missense	distal	-3	no	37.457	33.746	EPSD	COSMIC;GDSC;CCLE	31.796	Down-regulation
AGC_DMPK_ROCK_ROCK1_ST	P15311	EZR	Q13464	ROCK1	T533	E537K	537	Missense	distal	4	no	31.196	33.127	EPSD	COSMIC;CCLE	31.796	Gain
AGC_DMPK_ROCK_ROCK1_ST	P15311	EZR	Q13464	ROCK1	T576	K577N	577	Missense	proximal	1	no	32.964	33.811	EPSD	COSMIC	31.796	Up-regulation
AGC_DMPK_ROCK_ROCK1_ST	P14136	GFAP	Q13464	ROCK1	S38	P44H	44	Missense	distal	6	no	39.789	39.400	PhosphoSitePlus;EPSD	COSMIC	31.796	Down-regulation
AGC_DMPK_ROCK_ROCK1_ST	P14136	GFAP	Q13464	ROCK1	S38	T35P	35	Missense	distal	-3	no	39.789	29.550	PhosphoSitePlus;EPSD	COSMIC;GDSC	31.796	Loss
AGC_DMPK_ROCK_ROCK1_ST	P60484	PTEN	Q13464	ROCK1	S170	I168F	168	Missense	proximal	-2	no	22.150	32.564	EPSD	COSMIC	31.796	Gain
AGC_DMPK_ROCK_ROCK1_ST	P60484	PTEN	Q13464	ROCK1	S179	L181Q	181	Missense	proximal	2	no	43.618	45.656	EPSD	COSMIC	31.796	Up-regulation
AGC_DMPK_ROCK_ROCK1_ST	P60484	PTEN	Q13464	ROCK1	S179	Y176F	176	Missense	distal	-3	no	43.618	33.525	EPSD	COSMIC	31.796	Down-regulation
AGC_DMPK_ROCK_ROCK1_ST	P60484	PTEN	Q13464	ROCK1	S179	Y174D	174	Missense	distal	-5	no	43.618	42.224	EPSD	COSMIC	31.796	Down-regulation
AGC_DMPK_ROCK_ROCK1_ST	P60484	PTEN	Q13464	ROCK1	S179	Y174N	174	Missense	distal	-5	no	43.618	42.991	EPSD	COSMIC	31.796	Down-regulation
AGC_DMPK_ROCK_ROCK1_ST	P60484	PTEN	Q13464	ROCK1	S179	R172W	172	Missense	distal	-7	no	43.618	43.373	EPSD	COSMIC	31.796	Down-regulation
AGC_DMPK_ROCK_ROCK1_ST	P60484	PTEN	Q13464	ROCK1	S179	R173P	173	Missense	distal	-6	no	43.618	38.286	EPSD	COSMIC;GDSC;CCLE	31.796	Down-regulation
AGC_DMPK_ROCK_ROCK1_ST	P60484	PTEN	Q13464	ROCK1	S179	L182F	182	Missense	distal	3	no	43.618	43.645	EPSD	COSMIC	31.796	Up-regulation
AGC_DMPK_ROCK_ROCK1_ST	P60484	PTEN	Q13464	ROCK1	S179	H185Y	185	Missense	distal	6	no	43.618	44.054	EPSD	COSMIC	31.796	Up-regulation
AGC_DMPK_ROCK_ROCK1_ST	P60484	PTEN	Q13464	ROCK1	S179	V175M	175	Missense	distal	-4	no	43.618	44.849	EPSD	COSMIC	31.796	Up-regulation
AGC_DMPK_ROCK_ROCK1_ST	P60484	PTEN	Q13464	ROCK1	S179	N184I	184	Missense	distal	5	no	43.618	43.504	EPSD	COSMIC	31.796	Down-regulation
AGC_DMPK_ROCK_ROCK1_ST	P60484	PTEN	Q13464	ROCK1	S179	Y178H	178	Missense	proximal	-1	no	43.618	43.404	EPSD	COSMIC	31.796	Down-regulation
AGC_DMPK_ROCK_ROCK1_ST	P60484	PTEN	Q13464	ROCK1	S179	L182V	182	Missense	distal	3	no	43.618	43.734	EPSD	COSMIC	31.796	Up-regulation
AGC_DMPK_ROCK_ROCK1_ST	P60484	PTEN	Q13464	ROCK1	S179	Y177H	177	Missense	proximal	-2	no	43.618	37.060	EPSD	COSMIC	31.796	Down-regulation
AGC_DMPK_ROCK_ROCK1_ST	P60484	PTEN	Q13464	ROCK1	S179	K183N	183	Missense	distal	4	no	43.618	42.231	EPSD	COSMIC	31.796	Down-regulation
AGC_DMPK_ROCK_ROCK1_ST	P60484	PTEN	Q13464	ROCK1	S179	S179I	179	Missense	central	0	yes	43.618	0.000	EPSD	COSMIC	31.796	Loss
AGC_DMPK_ROCK_ROCK1_ST	P60484	PTEN	Q13464	ROCK1	S179	Y176C	176	Missense	distal	-3	no	43.618	23.748	EPSD	COSMIC	31.796	Loss
AGC_DMPK_ROCK_ROCK1_ST	P60484	PTEN	Q13464	ROCK1	S179	Y178D	178	Missense	proximal	-1	no	43.618	42.225	EPSD	COSMIC	31.796	Down-regulation
AGC_DMPK_ROCK_ROCK1_ST	P60484	PTEN	Q13464	ROCK1	S179	V175A	175	Missense	distal	-4	no	43.618	44.145	EPSD	COSMIC	31.796	Up-regulation
AGC_DMPK_ROCK_ROCK1_ST	P60484	PTEN	Q13464	ROCK1	S179	Y174C	174	Missense	distal	-5	no	43.618	39.312	EPSD	COSMIC	31.796	Down-regulation
AGC_DMPK_ROCK_ROCK1_ST	P60484	PTEN	Q13464	ROCK1	S179	Y178F	178	Missense	proximal	-1	no	43.618	42.029	EPSD	COSMIC	31.796	Down-regulation
AGC_DMPK_ROCK_ROCK1_ST	P60484	PTEN	Q13464	ROCK1	S179	R173S	173	Missense	distal	-6	no	43.618	41.011	EPSD	COSMIC	31.796	Down-regulation
AGC_DMPK_ROCK_ROCK1_ST	P60484	PTEN	Q13464	ROCK1	S179	L181R	181	Missense	proximal	2	no	43.618	46.811	EPSD	COSMIC	31.796	Up-regulation
AGC_DMPK_ROCK_ROCK1_ST	P60484	PTEN	Q13464	ROCK1	S179	Y178N	178	Missense	proximal	-1	no	43.618	43.663	EPSD	COSMIC	31.796	Up-regulation
AGC_DMPK_ROCK_ROCK1_ST	P60484	PTEN	Q13464	ROCK1	S179	Y174H	174	Missense	distal	-5	no	43.618	43.718	EPSD	COSMIC	31.796	Up-regulation
AGC_DMPK_ROCK_ROCK1_ST	P60484	PTEN	Q13464	ROCK1	S227	R234Q	234	Missense	distal	7	no	33.700	34.704	EPSD	COSMIC	31.796	Up-regulation
AGC_DMPK_ROCK_ROCK1_ST	P60484	PTEN	Q13464	ROCK1	S227	S226F	226	Missense	proximal	-1	no	33.700	30.497	EPSD	COSMIC	31.796	Loss
AGC_DMPK_ROCK_ROCK1_ST	P60484	PTEN	Q13464	ROCK1	S227	S227F	227	Missense	central	0	yes	33.700	0.000	EPSD	COSMIC	31.796	Loss
AGC_DMPK_ROCK_ROCK1_ST	P60484	PTEN	Q13464	ROCK1	S227	G230R	230	Missense	distal	3	no	33.700	33.759	EPSD	COSMIC	31.796	Up-regulation
AGC_DMPK_ROCK_ROCK1_ST	P60484	PTEN	Q13464	ROCK1	S227	Y225H	225	Missense	proximal	-2	no	33.700	27.142	EPSD	COSMIC	31.796	Loss
AGC_DMPK_ROCK_ROCK1_ST	P60484	PTEN	Q13464	ROCK1	S227	R233G	233	Missense	distal	6	no	33.700	34.774	EPSD	COSMIC;CCLE	31.796	Up-regulation
AGC_DMPK_ROCK_ROCK1_ST	P60484	PTEN	Q13464	ROCK1	S227	R234G	234	Missense	distal	7	no	33.700	35.060	EPSD	COSMIC;CCLE	31.796	Up-regulation
AGC_DMPK_ROCK_ROCK1_ST	P60484	PTEN	Q13464	ROCK1	S227	V222A	222	Missense	distal	-5	no	33.700	36.511	EPSD	COSMIC	31.796	Up-regulation
AGC_DMPK_ROCK_ROCK1_ST	P60484	PTEN	Q13464	ROCK1	S227	P231S	231	Missense	distal	4	no	33.700	33.976	EPSD	COSMIC	31.796	Up-regulation
AGC_DMPK_ROCK_ROCK1_ST	P60484	PTEN	Q13464	ROCK1	S227	R234W	234	Missense	distal	7	no	33.700	35.238	EPSD	COSMIC	31.796	Up-regulation
AGC_DMPK_ROCK_ROCK1_ST	P60484	PTEN	Q13464	ROCK1	S227	Y225C	225	Missense	proximal	-2	no	33.700	5.420	EPSD	COSMIC	31.796	Loss
AGC_DMPK_ROCK_ROCK1_ST	P60484	PTEN	Q13464	ROCK1	S227	G230V	230	Missense	distal	3	no	33.700	33.579	EPSD	COSMIC;CCLE	31.796	Down-regulation
AGC_DMPK_ROCK_ROCK1_ST	P60484	PTEN	Q13464	ROCK1	S227	Y225D	225	Missense	proximal	-2	no	33.700	26.011	EPSD	COSMIC	31.796	Loss
AGC_DMPK_ROCK_ROCK1_ST	P60484	PTEN	Q13464	ROCK1	S227	R234L	234	Missense	distal	7	no	33.700	35.023	EPSD	COSMIC	31.796	Up-regulation
AGC_DMPK_ROCK_ROCK1_ST	P60484	PTEN	Q13464	ROCK1	S227	V222M	222	Missense	distal	-5	no	33.700	37.261	EPSD	COSMIC	31.796	Up-regulation
AGC_DMPK_ROCK_ROCK1_ST	P60484	PTEN	Q13464	ROCK1	S227	T232P	232	Missense	distal	5	no	33.700	34.260	EPSD	COSMIC	31.796	Up-regulation
AGC_DMPK_ROCK_ROCK1_ST	P60484	PTEN	Q13464	ROCK1	S227	S229L	229	Missense	proximal	2	no	33.700	31.373	EPSD	COSMIC	31.796	Loss
AGC_DMPK_ROCK_ROCK1_ST	P60484	PTEN	Q13464	ROCK1	S229	R234Q	234	Missense	distal	5	no	35.730	36.569	PhosphoSitePlus;EPSD	COSMIC	31.796	Up-regulation
AGC_DMPK_ROCK_ROCK1_ST	P60484	PTEN	Q13464	ROCK1	S229	S226F	226	Missense	distal	-3	no	35.730	30.812	PhosphoSitePlus;EPSD	COSMIC	31.796	Loss
AGC_DMPK_ROCK_ROCK1_ST	P60484	PTEN	Q13464	ROCK1	S229	D236E	236	Missense	distal	7	no	35.730	35.484	PhosphoSitePlus;EPSD	COSMIC	31.796	Down-regulation
AGC_DMPK_ROCK_ROCK1_ST	P60484	PTEN	Q13464	ROCK1	S229	S227F	227	Missense	proximal	-2	no	35.730	37.285	PhosphoSitePlus;EPSD	COSMIC	31.796	Up-regulation
AGC_DMPK_ROCK_ROCK1_ST	P60484	PTEN	Q13464	ROCK1	S229	G230R	230	Missense	proximal	1	no	35.730	35.264	PhosphoSitePlus;EPSD	COSMIC	31.796	Down-regulation
AGC_DMPK_ROCK_ROCK1_ST	P60484	PTEN	Q13464	ROCK1	S229	Y225H	225	Missense	distal	-4	no	35.730	35.586	PhosphoSitePlus;EPSD	COSMIC	31.796	Down-regulation
AGC_DMPK_ROCK_ROCK1_ST	P60484	PTEN	Q13464	ROCK1	S229	R233G	233	Missense	distal	4	no	35.730	35.298	PhosphoSitePlus;EPSD	COSMIC;CCLE	31.796	Down-regulation
AGC_DMPK_ROCK_ROCK1_ST	P60484	PTEN	Q13464	ROCK1	S229	R234G	234	Missense	distal	5	no	35.730	36.135	PhosphoSitePlus;EPSD	COSMIC;CCLE	31.796	Up-regulation
AGC_DMPK_ROCK_ROCK1_ST	P60484	PTEN	Q13464	ROCK1	S229	V222A	222	Missense	distal	-7	no	35.730	35.787	PhosphoSitePlus;EPSD	COSMIC	31.796	Up-regulation
AGC_DMPK_ROCK_ROCK1_ST	P60484	PTEN	Q13464	ROCK1	S229	E235G	235	Missense	distal	6	no	35.730	35.710	PhosphoSitePlus;EPSD	COSMIC	31.796	Down-regulation
AGC_DMPK_ROCK_ROCK1_ST	P60484	PTEN	Q13464	ROCK1	S229	P231S	231	Missense	proximal	2	no	35.730	36.997	PhosphoSitePlus;EPSD	COSMIC	31.796	Up-regulation
AGC_DMPK_ROCK_ROCK1_ST	P60484	PTEN	Q13464	ROCK1	S229	R234W	234	Missense	distal	5	no	35.730	36.630	PhosphoSitePlus;EPSD	COSMIC	31.796	Up-regulation
AGC_DMPK_ROCK_ROCK1_ST	P60484	PTEN	Q13464	ROCK1	S229	E235K	235	Missense	distal	6	no	35.730	35.044	PhosphoSitePlus;EPSD	COSMIC	31.796	Down-regulation
AGC_DMPK_ROCK_ROCK1_ST	P60484	PTEN	Q13464	ROCK1	S229	Y225C	225	Missense	distal	-4	no	35.730	33.396	PhosphoSitePlus;EPSD	COSMIC	31.796	Down-regulation
AGC_DMPK_ROCK_ROCK1_ST	P60484	PTEN	Q13464	ROCK1	S229	G230V	230	Missense	proximal	1	no	35.730	36.430	PhosphoSitePlus;EPSD	COSMIC;CCLE	31.796	Up-regulation
AGC_DMPK_ROCK_ROCK1_ST	P60484	PTEN	Q13464	ROCK1	S229	Y225D	225	Missense	distal	-4	no	35.730	35.429	PhosphoSitePlus;EPSD	COSMIC	31.796	Down-regulation
AGC_DMPK_ROCK_ROCK1_ST	P60484	PTEN	Q13464	ROCK1	S229	R234L	234	Missense	distal	5	no	35.730	36.977	PhosphoSitePlus;EPSD	COSMIC	31.796	Up-regulation
AGC_DMPK_ROCK_ROCK1_ST	P60484	PTEN	Q13464	ROCK1	S229	V222M	222	Missense	distal	-7	no	35.730	35.755	PhosphoSitePlus;EPSD	COSMIC	31.796	Up-regulation
AGC_DMPK_ROCK_ROCK1_ST	P60484	PTEN	Q13464	ROCK1	S229	T232P	232	Missense	distal	3	no	35.730	35.600	PhosphoSitePlus;EPSD	COSMIC	31.796	Down-regulation
AGC_DMPK_ROCK_ROCK1_ST	P60484	PTEN	Q13464	ROCK1	S229	S229L	229	Missense	central	0	yes	35.730	0.000	PhosphoSitePlus;EPSD	COSMIC	31.796	Loss
AGC_DMPK_ROCK_ROCK1_ST	P60484	PTEN	Q13464	ROCK1	T232	R234Q	234	Missense	proximal	2	no	37.654	36.499	EPSD;PhosphoSitePlus	COSMIC	31.796	Down-regulation
AGC_DMPK_ROCK_ROCK1_ST	P60484	PTEN	Q13464	ROCK1	T232	S226F	226	Missense	distal	-6	no	37.654	33.435	EPSD;PhosphoSitePlus	COSMIC	31.796	Down-regulation
AGC_DMPK_ROCK_ROCK1_ST	P60484	PTEN	Q13464	ROCK1	T232	D236E	236	Missense	distal	4	no	37.654	37.344	EPSD;PhosphoSitePlus	COSMIC	31.796	Down-regulation
AGC_DMPK_ROCK_ROCK1_ST	P60484	PTEN	Q13464	ROCK1	T232	S227F	227	Missense	distal	-5	no	37.654	36.352	EPSD;PhosphoSitePlus	COSMIC	31.796	Down-regulation
AGC_DMPK_ROCK_ROCK1_ST	P60484	PTEN	Q13464	ROCK1	T232	G230R	230	Missense	proximal	-2	no	37.654	47.410	EPSD;PhosphoSitePlus	COSMIC	31.796	Up-regulation
AGC_DMPK_ROCK_ROCK1_ST	P60484	PTEN	Q13464	ROCK1	T232	F238L	238	Missense	distal	6	no	37.654	36.850	EPSD;PhosphoSitePlus	COSMIC	31.796	Down-regulation
AGC_DMPK_ROCK_ROCK1_ST	P60484	PTEN	Q13464	ROCK1	T232	Y225H	225	Missense	distal	-7	no	37.654	37.668	EPSD;PhosphoSitePlus	COSMIC	31.796	Up-regulation
AGC_DMPK_ROCK_ROCK1_ST	P60484	PTEN	Q13464	ROCK1	T232	R233G	233	Missense	proximal	1	no	37.654	38.120	EPSD;PhosphoSitePlus	COSMIC;CCLE	31.796	Up-regulation
AGC_DMPK_ROCK_ROCK1_ST	P60484	PTEN	Q13464	ROCK1	T232	R234G	234	Missense	proximal	2	no	37.654	37.007	EPSD;PhosphoSitePlus	COSMIC;CCLE	31.796	Down-regulation
AGC_DMPK_ROCK_ROCK1_ST	P60484	PTEN	Q13464	ROCK1	T232	E235G	235	Missense	distal	3	no	37.654	37.858	EPSD;PhosphoSitePlus	COSMIC	31.796	Up-regulation
AGC_DMPK_ROCK_ROCK1_ST	P60484	PTEN	Q13464	ROCK1	T232	P231S	231	Missense	proximal	-1	no	37.654	39.673	EPSD;PhosphoSitePlus	COSMIC	31.796	Up-regulation
AGC_DMPK_ROCK_ROCK1_ST	P60484	PTEN	Q13464	ROCK1	T232	R234W	234	Missense	proximal	2	no	37.654	35.766	EPSD;PhosphoSitePlus	COSMIC	31.796	Down-regulation
AGC_DMPK_ROCK_ROCK1_ST	P60484	PTEN	Q13464	ROCK1	T232	E235K	235	Missense	distal	3	no	37.654	37.944	EPSD;PhosphoSitePlus	COSMIC	31.796	Up-regulation
AGC_DMPK_ROCK_ROCK1_ST	P60484	PTEN	Q13464	ROCK1	T232	Y225C	225	Missense	distal	-7	no	37.654	37.577	EPSD;PhosphoSitePlus	COSMIC	31.796	Down-regulation
AGC_DMPK_ROCK_ROCK1_ST	P60484	PTEN	Q13464	ROCK1	T232	G230V	230	Missense	proximal	-2	no	37.654	31.045	EPSD;PhosphoSitePlus	COSMIC;CCLE	31.796	Loss
AGC_DMPK_ROCK_ROCK1_ST	P60484	PTEN	Q13464	ROCK1	T232	Y225D	225	Missense	distal	-7	no	37.654	37.652	EPSD;PhosphoSitePlus	COSMIC	31.796	Down-regulation
AGC_DMPK_ROCK_ROCK1_ST	P60484	PTEN	Q13464	ROCK1	T232	R234L	234	Missense	proximal	2	no	37.654	34.461	EPSD;PhosphoSitePlus	COSMIC	31.796	Down-regulation
AGC_DMPK_ROCK_ROCK1_ST	P60484	PTEN	Q13464	ROCK1	T232	T232P	232	Missense	central	0	yes	37.654	0.000	EPSD;PhosphoSitePlus	COSMIC	31.796	Loss
AGC_DMPK_ROCK_ROCK1_ST	P60484	PTEN	Q13464	ROCK1	T232	S229L	229	Missense	distal	-3	no	37.654	36.771	EPSD;PhosphoSitePlus	COSMIC	31.796	Down-regulation
AGC_DMPK_ROCK_ROCK1_ST	P60484	PTEN	Q13464	ROCK1	S338	N334D	334	Missense	distal	-4	no	42.148	41.787	EPSD	COSMIC	31.796	Down-regulation
AGC_DMPK_ROCK_ROCK1_ST	P60484	PTEN	Q13464	ROCK1	S338	F337L	337	Missense	proximal	-1	no	42.148	42.598	EPSD	COSMIC	31.796	Up-regulation
AGC_DMPK_ROCK_ROCK1_ST	P60484	PTEN	Q13464	ROCK1	S338	F341L	341	Missense	distal	3	no	42.148	42.121	EPSD	COSMIC	31.796	Down-regulation
AGC_DMPK_ROCK_ROCK1_ST	P60484	PTEN	Q13464	ROCK1	S338	P339S	339	Missense	proximal	1	no	42.148	42.345	EPSD	COSMIC	31.796	Up-regulation
AGC_DMPK_ROCK_ROCK1_ST	P60484	PTEN	Q13464	ROCK1	S338	S338Y	338	Missense	central	0	yes	42.148	0.000	EPSD	COSMIC	31.796	Loss
AGC_DMPK_ROCK_ROCK1_ST	P60484	PTEN	Q13464	ROCK1	S338	F341I	341	Missense	distal	3	no	42.148	42.204	EPSD	COSMIC	31.796	Up-regulation
AGC_DMPK_ROCK_ROCK1_ST	P60484	PTEN	Q13464	ROCK1	S338	F341Y	341	Missense	distal	3	no	42.148	42.245	EPSD	COSMIC	31.796	Up-regulation
AGC_DMPK_ROCK_ROCK1_ST	P60484	PTEN	Q13464	ROCK1	S338	P339L	339	Missense	proximal	1	no	42.148	42.596	EPSD	COSMIC	31.796	Up-regulation
AGC_DMPK_ROCK_ROCK1_ST	P60484	PTEN	Q13464	ROCK1	S338	N334S	334	Missense	distal	-4	no	42.148	41.978	EPSD	COSMIC	31.796	Down-regulation
AGC_DMPK_ROCK_ROCK1_ST	P60484	PTEN	Q13464	ROCK1	S338	N334Y	334	Missense	distal	-4	no	42.148	42.088	EPSD	COSMIC	31.796	Down-regulation
AGC_DMPK_ROCK_ROCK1_ST	P60484	PTEN	Q13464	ROCK1	S338	K344R	344	Missense	distal	6	no	42.148	41.741	EPSD	COSMIC	31.796	Down-regulation
AGC_DMPK_ROCK_ROCK1_ST	P60484	PTEN	Q13464	ROCK1	S338	D331H	331	Missense	distal	-7	no	42.148	42.165	EPSD	COSMIC	31.796	Up-regulation
AGC_DMPK_ROCK_ROCK1_ST	P60484	PTEN	Q13464	ROCK1	S338	D331G	331	Missense	distal	-7	no	42.148	42.163	EPSD	COSMIC	31.796	Up-regulation
AGC_DMPK_ROCK_ROCK1_ST	P60484	PTEN	Q13464	ROCK1	S338	Y336C	336	Missense	proximal	-2	no	42.148	13.868	EPSD	COSMIC	31.796	Loss
AGC_DMPK_ROCK_ROCK1_ST	P60484	PTEN	Q13464	ROCK1	S338	V343G	343	Missense	distal	5	no	42.148	41.322	EPSD	COSMIC	31.796	Down-regulation
AGC_DMPK_ROCK_ROCK1_ST	P60484	PTEN	Q13464	ROCK1	S338	S338C	338	Missense	central	0	yes	42.148	0.000	EPSD	COSMIC	31.796	Loss
AGC_DMPK_ROCK_ROCK1_ST	P60484	PTEN	Q13464	ROCK1	S338	Y336F	336	Missense	proximal	-2	no	42.148	35.280	EPSD	COSMIC	31.796	Down-regulation
AGC_DMPK_ROCK_ROCK1_ST	P60484	PTEN	Q13464	ROCK1	S338	A333V	333	Missense	distal	-5	no	42.148	39.337	EPSD	COSMIC	31.796	Down-regulation
AGC_DMPK_ROCK_ROCK1_ST	P60484	PTEN	Q13464	ROCK1	S360	P357Q	357	Missense	distal	-3	no	23.239	36.126	EPSD	COSMIC	31.796	Gain
AGC_DMPK_ROCK_ROCK1_ST	P60484	PTEN	Q13464	ROCK1	S380	D375N	375	Missense	distal	-5	no	37.938	38.705	EPSD	COSMIC	31.796	Up-regulation
AGC_DMPK_ROCK_ROCK1_ST	P60484	PTEN	Q13464	ROCK1	S380	T383I	383	Missense	distal	3	no	37.938	37.759	EPSD	COSMIC	31.796	Down-regulation
AGC_DMPK_ROCK_ROCK1_ST	P60484	PTEN	Q13464	ROCK1	S380	D384N	384	Missense	distal	4	no	37.938	38.172	EPSD	COSMIC	31.796	Up-regulation
AGC_DMPK_ROCK_ROCK1_ST	P60484	PTEN	Q13464	ROCK1	S380	T382S	382	Missense	proximal	2	no	37.938	37.487	EPSD	COSMIC	31.796	Down-regulation
AGC_DMPK_ROCK_ROCK1_ST	P60484	PTEN	Q13464	ROCK1	S380	D384G	384	Missense	distal	4	no	37.938	39.087	EPSD	COSMIC	31.796	Up-regulation
AGC_DMPK_ROCK_ROCK1_ST	P17661	DES	Q13464	ROCK1	S12	S8N	8	Missense	distal	-4	no	38.150	38.320	EPSD;PhosphoSitePlus	COSMIC	31.796	Up-regulation
AGC_DMPK_ROCK_ROCK1_ST	P17661	DES	Q13464	ROCK1	S13	S8N	8	Missense	distal	-5	no	32.838	33.157	EPSD	COSMIC	31.796	Up-regulation
AGC_DMPK_ROCK_ROCK1_ST	P17661	DES	Q13464	ROCK1	S60	S57L	57	Missense	distal	-3	no	45.968	45.085	EPSD;PhosphoSitePlus	COSMIC;GDSC	31.796	Down-regulation
AGC_DMPK_ROCK_ROCK1_ST	P17661	DES	Q13464	ROCK1	S60	G62R	62	Missense	proximal	2	no	45.968	46.614	EPSD;PhosphoSitePlus	COSMIC	31.796	Up-regulation
AGC_DMPK_ROCK_ROCK1_ST	P17661	DES	Q13464	ROCK1	S60	S60L	60	Missense	central	0	yes	45.968	0.000	EPSD;PhosphoSitePlus	COSMIC	31.796	Loss
AGC_DMPK_ROCK_ROCK1_ST	P17661	DES	Q13464	ROCK1	S60	G65S	65	Missense	distal	5	no	45.968	46.313	EPSD;PhosphoSitePlus	COSMIC;GDSC;CCLE	31.796	Up-regulation
AGC_DMPK_ROCK_ROCK1_ST	P17661	DES	Q13464	ROCK1	S60	G64R	64	Missense	distal	4	no	45.968	46.399	EPSD;PhosphoSitePlus	COSMIC;CCLE	31.796	Up-regulation
AGC_DMPK_ROCK_ROCK1_ST	P17661	DES	Q13464	ROCK1	S60	G65D	65	Missense	distal	5	no	45.968	46.554	EPSD;PhosphoSitePlus	COSMIC	31.796	Up-regulation
AGC_DMPK_ROCK_ROCK1_ST	P17661	DES	Q13464	ROCK1	S68	G62R	62	Missense	distal	-6	no	31.988	33.055	EPSD	COSMIC	31.796	Up-regulation
AGC_DMPK_ROCK_ROCK1_ST	P17661	DES	Q13464	ROCK1	S68	G65S	65	Missense	distal	-3	no	31.988	31.590	EPSD	COSMIC;GDSC;CCLE	31.796	Loss
AGC_DMPK_ROCK_ROCK1_ST	P17661	DES	Q13464	ROCK1	S68	G64R	64	Missense	distal	-4	no	31.988	34.778	EPSD	COSMIC;CCLE	31.796	Up-regulation
AGC_DMPK_ROCK_ROCK1_ST	P17661	DES	Q13464	ROCK1	S68	G65D	65	Missense	distal	-3	no	31.988	33.400	EPSD	COSMIC	31.796	Up-regulation
AGC_DMPK_ROCK_ROCK1_ST	P17661	DES	Q13464	ROCK1	S81	E87K	87	Missense	distal	6	no	34.041	33.354	EPSD	COSMIC	31.796	Down-regulation
AGC_DMPK_ROCK_ROCK1_ST	P17661	DES	Q13464	ROCK1	S438	T445M	445	Missense	distal	7	no	32.643	32.525	EPSD	COSMIC;CCLE	31.796	Down-regulation
AGC_DMPK_ROCK_ROCK1_ST	P17661	DES	Q13464	ROCK1	S438	P433L	433	Missense	distal	-5	no	32.643	33.665	EPSD	COSMIC	31.796	Up-regulation
AGC_DMPK_ROCK_ROCK1_ST	Q14CB8	ARHGAP19	Q13464	ROCK1	S358	R355Q	355	Missense	distal	-3	no	36.016	31.133	EPSD	COSMIC;GDSC	31.796	Loss
AGC_DMPK_ROCK_ROCK1_ST	Q14CB8	ARHGAP19	Q13464	ROCK1	S358	R355W	355	Missense	distal	-3	no	36.016	26.855	EPSD	COSMIC	31.796	Loss
AGC_DMPK_ROCK_ROCK1_ST	Q14CB8	ARHGAP19	Q13464	ROCK1	S422	S420C	420	Missense	proximal	-2	no	36.767	16.909	PhosphoSitePlus	COSMIC	31.796	Loss
AGC_DMPK_ROCK_ROCK1_ST	Q14CB8	ARHGAP19	Q13464	ROCK1	S424	S420C	420	Missense	distal	-4	no	34.748	32.524	EPSD	COSMIC	31.796	Down-regulation
AGC_DMPK_ROCK_ROCK1_ST	Q14CB8	ARHGAP19	Q13464	ROCK1	S424	V431G	431	Missense	distal	7	no	34.748	34.203	EPSD	COSMIC	31.796	Down-regulation
AGC_DMPK_ROCK_ROCK1_ST	Q14CB8	ARHGAP19	Q13464	ROCK1	S438	V431G	431	Missense	distal	-7	no	35.741	35.809	EPSD	COSMIC	31.796	Up-regulation
AGC_DMPK_ROCK_ROCK1_ST	Q14CB8	ARHGAP19	Q13464	ROCK1	T446	S449C	449	Missense	distal	3	no	33.960	33.903	EPSD	COSMIC	31.796	Down-regulation
AGC_DMPK_ROCK_ROCK1_ST	O14950	MYL12B	Q13464	ROCK1	T10	K12N	12	Missense	proximal	2	no	34.832	32.836	EPSD	COSMIC	31.796	Down-regulation
AGC_DMPK_ROCK_ROCK1_ST	O14950	MYL12B	Q13464	ROCK1	T11	K12N	12	Missense	proximal	1	no	36.960	37.806	EPSD	COSMIC	31.796	Up-regulation
AGC_DMPK_ROCK_ROCK1_ST	O14950	MYL12B	Q13464	ROCK1	T19	M25L	25	Missense	distal	6	no	51.827	51.473	EPSD;PhosphoSitePlus	COSMIC	31.796	Down-regulation
AGC_DMPK_ROCK_ROCK1_ST	O14950	MYL12B	Q13464	ROCK1	T19	K12N	12	Missense	distal	-7	no	51.827	51.705	EPSD;PhosphoSitePlus	COSMIC	31.796	Down-regulation
AGC_DMPK_ROCK_ROCK1_ST	O14950	MYL12B	Q13464	ROCK1	S20	M25L	25	Missense	distal	5	no	40.125	40.453	PhosphoSitePlus;EPSD	COSMIC	31.796	Up-regulation
AGC_DMPK_ROCK_ROCK1_ST	Q16555	DPYSL2	Q13464	ROCK1	S363	R361Q	361	Missense	proximal	-2	no	35.420	22.250	EPSD	COSMIC	31.796	Loss
AGC_DMPK_ROCK_ROCK1_ST	Q16555	DPYSL2	Q13464	ROCK1	S363	D367N	367	Missense	distal	4	no	35.420	35.654	EPSD	COSMIC	31.796	Up-regulation
AGC_DMPK_ROCK_ROCK1_ST	Q16555	DPYSL2	Q13464	ROCK1	S427	L429F	429	Missense	proximal	2	no	33.068	33.619	EPSD	COSMIC	31.796	Up-regulation
AGC_DMPK_ROCK_ROCK1_ST	Q16555	DPYSL2	Q13464	ROCK1	T555	N549S	549	Missense	distal	-6	no	36.149	37.294	PhosphoSitePlus	COSMIC	31.796	Up-regulation
AGC_DMPK_ROCK_ROCK1_ST	Q16555	DPYSL2	Q13464	ROCK1	T555	P561L	561	Missense	distal	6	no	36.149	35.918	PhosphoSitePlus	COSMIC	31.796	Down-regulation
AGC_DMPK_ROCK_ROCK1_ST	Q16555	DPYSL2	Q13464	ROCK1	T555	R557C	557	Missense	proximal	2	no	36.149	33.635	PhosphoSitePlus	COSMIC	31.796	Down-regulation
AGC_DMPK_ROCK_ROCK1_ST	Q16555	DPYSL2	Q13464	ROCK1	T555	P561F	561	Missense	distal	6	no	36.149	36.722	PhosphoSitePlus	COSMIC	31.796	Up-regulation
AGC_DMPK_ROCK_ROCK1_ST	Q16555	DPYSL2	Q13464	ROCK1	T555	R557H	557	Missense	proximal	2	no	36.149	33.995	PhosphoSitePlus	COSMIC	31.796	Down-regulation
AGC_DMPK_ROCK_ROCK1_ST	O14744	PRMT5	Q13464	ROCK1	S15	G17R	17	Missense	proximal	2	no	39.096	39.742	EPSD	COSMIC	31.796	Up-regulation
AGC_DMPK_ROCK_ROCK1_ST	O14744	PRMT5	Q13464	ROCK1	S16	G17R	17	Missense	proximal	1	no	37.015	36.549	EPSD	COSMIC	31.796	Down-regulation
AGC_DMPK_ROCK_ROCK1_ST	O14744	PRMT5	Q13464	ROCK1	T80	G75R	75	Missense	distal	-5	no	31.579	33.608	PhosphoSitePlus	COSMIC	31.796	Gain
AGC_DMPK_ROCK_ROCK1_ST	O14744	PRMT5	Q13464	ROCK1	T80	S87F	87	Missense	distal	7	no	31.579	31.936	PhosphoSitePlus	COSMIC	31.796	Gain
AGC_DMPK_ROCK_ROCK1_ST	P24844	MYL9	Q13464	ROCK1	T19	N21T	21	Missense	proximal	2	no	51.361	52.617	PhosphoSitePlus;EPSD	COSMIC	31.796	Up-regulation
AGC_DMPK_ROCK_ROCK1_ST	P24844	MYL9	Q13464	ROCK1	T19	P15S	15	Missense	distal	-4	no	51.361	52.738	PhosphoSitePlus;EPSD	COSMIC	31.796	Up-regulation
AGC_DMPK_ROCK_ROCK1_ST	P24844	MYL9	Q13464	ROCK1	T19	R14Q	14	Missense	distal	-5	no	51.361	49.888	PhosphoSitePlus;EPSD	COSMIC	31.796	Down-regulation
AGC_DMPK_ROCK_ROCK1_ST	P24844	MYL9	Q13464	ROCK1	S20	N21T	21	Missense	proximal	1	no	39.387	39.023	EPSD;PhosphoSitePlus	COSMIC	31.796	Down-regulation
AGC_DMPK_ROCK_ROCK1_ST	P24844	MYL9	Q13464	ROCK1	S20	P15S	15	Missense	distal	-5	no	39.387	41.061	EPSD;PhosphoSitePlus	COSMIC	31.796	Up-regulation
AGC_DMPK_ROCK_ROCK1_ST	P24844	MYL9	Q13464	ROCK1	S20	R14Q	14	Missense	distal	-6	no	39.387	35.462	EPSD;PhosphoSitePlus	COSMIC	31.796	Down-regulation
AGC_DMPK_ROCK_ROCK1_ST	P07737	PFN1	Q13464	ROCK1	S30	S30F	30	Missense	central	0	yes	33.777	0.000	EPSD	COSMIC	31.796	Loss
AGC_DMPK_ROCK_ROCK1_ST	P07737	PFN1	Q13464	ROCK1	S57	D55Y	55	Missense	proximal	-2	no	25.607	33.297	EPSD	COSMIC	31.796	Gain
AGC_DMPK_ROCK_ROCK1_ST	P07737	PFN1	Q13464	ROCK1	S58	D55Y	55	Missense	distal	-3	no	44.060	47.425	EPSD	COSMIC	31.796	Up-regulation
AGC_DMPK_ROCK_ROCK1_ST	P07737	PFN1	Q13464	ROCK1	S58	F59C	59	Missense	proximal	1	no	44.060	43.504	EPSD	COSMIC	31.796	Down-regulation
AGC_DMPK_ROCK_ROCK1_ST	P07737	PFN1	Q13464	ROCK1	S58	R56Q	56	Missense	proximal	-2	no	44.060	30.890	EPSD	COSMIC	31.796	Loss
AGC_DMPK_ROCK_ROCK1_ST	P35611	ADD1	Q13464	ROCK1	S133	P126A	126	Missense	distal	-7	no	40.124	40.201	EPSD	COSMIC	31.796	Up-regulation
AGC_DMPK_ROCK_ROCK1_ST	P35611	ADD1	Q13464	ROCK1	T480	G477E	477	Missense	distal	-3	no	36.112	34.148	EPSD;PhosphoSitePlus	COSMIC	31.796	Down-regulation
AGC_DMPK_ROCK_ROCK1_ST	P35611	ADD1	Q13464	ROCK1	T480	K474T	474	Missense	distal	-6	no	36.112	35.192	EPSD;PhosphoSitePlus	COSMIC	31.796	Down-regulation
AGC_DMPK_ROCK_ROCK1_ST	P35611	ADD1	Q13464	ROCK1	S483	G477E	477	Missense	distal	-6	no	36.513	30.224	EPSD	COSMIC	31.796	Loss
AGC_DMPK_ROCK_ROCK1_ST	P35611	ADD1	Q13464	ROCK1	S726	S726L	726	Missense	central	0	yes	34.478	0.000	EPSD	COSMIC	31.796	Loss
AGC_DMPK_ROCK_ROCK1_ST	P26038	MSN	Q13464	ROCK1	T66	R71W	71	Missense	distal	5	no	36.764	37.664	EPSD	COSMIC	31.796	Up-regulation
AGC_DMPK_ROCK_ROCK1_ST	P26038	MSN	Q13464	ROCK1	T66	T66A	66	Missense	central	0	yes	36.764	0.000	EPSD	COSMIC	31.796	Loss
AGC_DMPK_ROCK_ROCK1_ST	P26038	MSN	Q13464	ROCK1	S74	F80L	80	Missense	distal	6	no	33.231	32.427	EPSD	COSMIC	31.796	Down-regulation
AGC_DMPK_ROCK_ROCK1_ST	P26038	MSN	Q13464	ROCK1	S74	R71W	71	Missense	distal	-3	no	33.231	24.069	EPSD	COSMIC	31.796	Loss
AGC_DMPK_ROCK_ROCK1_ST	P26038	MSN	Q13464	ROCK1	S504	A498V	498	Missense	distal	-6	no	36.774	34.743	EPSD	COSMIC	31.796	Down-regulation
AGC_DMPK_ROCK_ROCK1_ST	P26038	MSN	Q13464	ROCK1	S504	R508H	508	Missense	distal	4	no	36.774	36.185	EPSD	COSMIC	31.796	Down-regulation
AGC_DMPK_ROCK_ROCK1_ST	P26038	MSN	Q13464	ROCK1	T558	R560H	560	Missense	proximal	2	no	34.154	31.999	PhosphoSitePlus	COSMIC;GDSC;CCLE	31.796	Down-regulation
AGC_DMPK_ROCK_ROCK1_ST	P26038	MSN	Q13464	ROCK1	T558	K555R	555	Missense	distal	-3	no	34.154	37.864	PhosphoSitePlus	COSMIC	31.796	Up-regulation
AGC_DMPK_ROCK_ROCK1_ST	P53671	LIMK2	Q13464	ROCK1	S283	R286C	286	Missense	distal	3	no	48.287	48.094	EPSD	COSMIC	31.796	Down-regulation
AGC_DMPK_ROCK_ROCK1_ST	P53671	LIMK2	Q13464	ROCK1	S283	R282C	282	Missense	proximal	-1	no	48.287	44.007	EPSD	COSMIC	31.796	Down-regulation
AGC_DMPK_ROCK_ROCK1_ST	P53671	LIMK2	Q13464	ROCK1	S283	R286H	286	Missense	distal	3	no	48.287	48.191	EPSD	COSMIC;CCLE	31.796	Down-regulation
AGC_DMPK_ROCK_ROCK1_ST	P53671	LIMK2	Q13464	ROCK1	S283	T278R	278	Missense	distal	-5	no	48.287	50.682	EPSD	COSMIC	31.796	Up-regulation
AGC_DMPK_ROCK_ROCK1_ST	P53671	LIMK2	Q13464	ROCK1	S283	R280M	280	Missense	distal	-3	no	48.287	40.773	EPSD	COSMIC	31.796	Down-regulation
AGC_DMPK_ROCK_ROCK1_ST	P53671	LIMK2	Q13464	ROCK1	S283	S283F	283	Missense	central	0	yes	48.287	0.000	EPSD	COSMIC	31.796	Loss
AGC_DMPK_ROCK_ROCK1_ST	P53671	LIMK2	Q13464	ROCK1	S283	S289R	289	Missense	distal	6	no	48.287	47.475	EPSD	COSMIC	31.796	Down-regulation
AGC_DMPK_ROCK_ROCK1_ST	P53671	LIMK2	Q13464	ROCK1	S283	R286Q	286	Missense	distal	3	no	48.287	48.105	EPSD	COSMIC	31.796	Down-regulation
AGC_DMPK_ROCK_ROCK1_ST	P53671	LIMK2	Q13464	ROCK1	S287	S291F	291	Missense	distal	4	no	36.978	35.441	EPSD	COSMIC	31.796	Down-regulation
AGC_DMPK_ROCK_ROCK1_ST	P53671	LIMK2	Q13464	ROCK1	S287	R286C	286	Missense	proximal	-1	no	36.978	32.697	EPSD	COSMIC	31.796	Down-regulation
AGC_DMPK_ROCK_ROCK1_ST	P53671	LIMK2	Q13464	ROCK1	S287	R282C	282	Missense	distal	-5	no	36.978	31.345	EPSD	COSMIC	31.796	Loss
AGC_DMPK_ROCK_ROCK1_ST	P53671	LIMK2	Q13464	ROCK1	S287	R286H	286	Missense	proximal	-1	no	36.978	34.410	EPSD	COSMIC;CCLE	31.796	Down-regulation
AGC_DMPK_ROCK_ROCK1_ST	P53671	LIMK2	Q13464	ROCK1	S287	R280M	280	Missense	distal	-7	no	36.978	36.770	EPSD	COSMIC	31.796	Down-regulation
AGC_DMPK_ROCK_ROCK1_ST	P53671	LIMK2	Q13464	ROCK1	S287	S283F	283	Missense	distal	-4	no	36.978	34.953	EPSD	COSMIC	31.796	Down-regulation
AGC_DMPK_ROCK_ROCK1_ST	P53671	LIMK2	Q13464	ROCK1	S287	S289R	289	Missense	proximal	2	no	36.978	37.844	EPSD	COSMIC	31.796	Up-regulation
AGC_DMPK_ROCK_ROCK1_ST	P53671	LIMK2	Q13464	ROCK1	S287	R286Q	286	Missense	proximal	-1	no	36.978	34.762	EPSD	COSMIC	31.796	Down-regulation
AGC_DMPK_ROCK_ROCK1_ST	P53671	LIMK2	Q13464	ROCK1	S289	S291F	291	Missense	proximal	2	no	33.551	31.774	EPSD	COSMIC	31.796	Loss
AGC_DMPK_ROCK_ROCK1_ST	P53671	LIMK2	Q13464	ROCK1	S289	R286C	286	Missense	distal	-3	no	33.551	8.266	EPSD	COSMIC	31.796	Loss
AGC_DMPK_ROCK_ROCK1_ST	P53671	LIMK2	Q13464	ROCK1	S289	R282C	282	Missense	distal	-7	no	33.551	33.297	EPSD	COSMIC	31.796	Down-regulation
AGC_DMPK_ROCK_ROCK1_ST	P53671	LIMK2	Q13464	ROCK1	S289	R286H	286	Missense	distal	-3	no	33.551	18.940	EPSD	COSMIC;CCLE	31.796	Loss
AGC_DMPK_ROCK_ROCK1_ST	P53671	LIMK2	Q13464	ROCK1	S289	G295D	295	Missense	distal	6	no	33.551	33.751	EPSD	COSMIC	31.796	Up-regulation
AGC_DMPK_ROCK_ROCK1_ST	P53671	LIMK2	Q13464	ROCK1	S289	S283F	283	Missense	distal	-6	no	33.551	29.332	EPSD	COSMIC	31.796	Loss
AGC_DMPK_ROCK_ROCK1_ST	P53671	LIMK2	Q13464	ROCK1	S289	S289R	289	Missense	central	0	yes	33.551	0.000	EPSD	COSMIC	31.796	Loss
AGC_DMPK_ROCK_ROCK1_ST	P53671	LIMK2	Q13464	ROCK1	S289	R286Q	286	Missense	distal	-3	no	33.551	28.668	EPSD	COSMIC	31.796	Loss
AGC_DMPK_ROCK_ROCK1_ST	P53671	LIMK2	Q13464	ROCK1	S291	S289R	289	Missense	proximal	-2	no	23.420	36.421	EPSD	COSMIC	31.796	Gain
AGC_DMPK_ROCK_ROCK1_ST	P53671	LIMK2	Q13464	ROCK1	S318	R311L	311	Missense	distal	-7	no	32.280	32.098	EPSD	COSMIC	31.796	Down-regulation
AGC_DMPK_ROCK_ROCK1_ST	P53671	LIMK2	Q13464	ROCK1	S318	R316C	316	Missense	proximal	-2	no	32.280	-0.578	EPSD	COSMIC;CCLE	31.796	Loss
AGC_DMPK_ROCK_ROCK1_ST	P53671	LIMK2	Q13464	ROCK1	S318	I325M	325	Missense	distal	7	no	32.280	32.473	EPSD	COSMIC	31.796	Up-regulation
AGC_DMPK_ROCK_ROCK1_ST	P53671	LIMK2	Q13464	ROCK1	T494	R493H	493	Missense	proximal	-1	no	33.672	31.104	EPSD	COSMIC	31.796	Loss
AGC_DMPK_ROCK_ROCK1_ST	P53671	LIMK2	Q13464	ROCK1	T494	R496H	496	Missense	proximal	2	no	33.672	31.518	EPSD	COSMIC;CCLE	31.796	Loss
AGC_DMPK_ROCK_ROCK1_ST	P53671	LIMK2	Q13464	ROCK1	T494	K491N	491	Missense	distal	-3	no	33.672	28.103	EPSD	COSMIC	31.796	Loss
AGC_DMPK_ROCK_ROCK1_ST	P53671	LIMK2	Q13464	ROCK1	T505	P510H	510	Missense	distal	5	no	56.361	55.687	PhosphoSitePlus	COSMIC	31.796	Down-regulation
AGC_DMPK_ROCK_ROCK1_ST	P53671	LIMK2	Q13464	ROCK1	T505	R503C	503	Missense	proximal	-2	no	56.361	23.503	PhosphoSitePlus	COSMIC	31.796	Loss
AGC_DMPK_ROCK_ROCK1_ST	O60237	PPP1R12B	Q13464	ROCK1	S29	L23P	23	Missense	distal	-6	no	39.622	40.185	EPSD	COSMIC	31.796	Up-regulation
AGC_DMPK_ROCK_ROCK1_ST	O60237	PPP1R12B	Q13464	ROCK1	S51	R49H	49	Missense	proximal	-2	no	41.048	29.913	EPSD	COSMIC;GDSC;CCLE	31.796	Loss
AGC_DMPK_ROCK_ROCK1_ST	O60237	PPP1R12B	Q13464	ROCK1	S420	R418S	418	Missense	proximal	-2	no	36.693	23.692	EPSD	COSMIC	31.796	Loss
AGC_DMPK_ROCK_ROCK1_ST	O60237	PPP1R12B	Q13464	ROCK1	S420	S415F	415	Missense	distal	-5	no	36.693	35.391	EPSD	COSMIC	31.796	Down-regulation
AGC_DMPK_ROCK_ROCK1_ST	O60237	PPP1R12B	Q13464	ROCK1	S420	G422V	422	Missense	proximal	2	no	36.693	35.651	EPSD	COSMIC	31.796	Down-regulation
AGC_DMPK_ROCK_ROCK1_ST	O60237	PPP1R12B	Q13464	ROCK1	T445	L442V	442	Missense	distal	-3	no	42.881	45.284	EPSD	COSMIC	31.796	Up-regulation
AGC_DMPK_ROCK_ROCK1_ST	O60237	PPP1R12B	Q13464	ROCK1	T445	G446D	446	Missense	proximal	1	no	42.881	43.584	EPSD	COSMIC	31.796	Up-regulation
AGC_DMPK_ROCK_ROCK1_ST	O60237	PPP1R12B	Q13464	ROCK1	S447	L442V	442	Missense	distal	-5	no	37.915	36.195	EPSD	COSMIC	31.796	Down-regulation
AGC_DMPK_ROCK_ROCK1_ST	O60237	PPP1R12B	Q13464	ROCK1	S447	G446D	446	Missense	proximal	-1	no	37.915	34.726	EPSD	COSMIC	31.796	Down-regulation
AGC_DMPK_ROCK_ROCK1_ST	O60237	PPP1R12B	Q13464	ROCK1	S472	R470C	470	Missense	proximal	-2	no	36.366	3.508	EPSD	COSMIC	31.796	Loss
AGC_DMPK_ROCK_ROCK1_ST	O60237	PPP1R12B	Q13464	ROCK1	S472	S466F	466	Missense	distal	-6	no	36.366	32.148	EPSD	COSMIC	31.796	Down-regulation
AGC_DMPK_ROCK_ROCK1_ST	O60237	PPP1R12B	Q13464	ROCK1	S472	S474I	474	Missense	proximal	2	no	36.366	34.239	EPSD	COSMIC	31.796	Down-regulation
AGC_DMPK_ROCK_ROCK1_ST	O60237	PPP1R12B	Q13464	ROCK1	S473	R470C	470	Missense	distal	-3	no	32.914	7.629	EPSD	COSMIC	31.796	Loss
AGC_DMPK_ROCK_ROCK1_ST	O60237	PPP1R12B	Q13464	ROCK1	S473	S466F	466	Missense	distal	-7	no	32.914	32.795	EPSD	COSMIC	31.796	Down-regulation
AGC_DMPK_ROCK_ROCK1_ST	O60237	PPP1R12B	Q13464	ROCK1	S473	S474I	474	Missense	proximal	1	no	32.914	32.692	EPSD	COSMIC	31.796	Down-regulation
AGC_DMPK_ROCK_ROCK1_ST	O60237	PPP1R12B	Q13464	ROCK1	S618	D625N	625	Missense	distal	7	no	37.825	37.995	EPSD	COSMIC	31.796	Up-regulation
AGC_DMPK_ROCK_ROCK1_ST	O60237	PPP1R12B	Q13464	ROCK1	S618	R624Q	624	Missense	distal	6	no	37.825	38.942	EPSD	COSMIC	31.796	Up-regulation
AGC_DMPK_ROCK_ROCK1_ST	O60237	PPP1R12B	Q13464	ROCK1	T621	D625N	625	Missense	distal	4	no	33.128	33.362	EPSD	COSMIC	31.796	Up-regulation
AGC_DMPK_ROCK_ROCK1_ST	O60237	PPP1R12B	Q13464	ROCK1	T621	R624Q	624	Missense	distal	3	no	33.128	32.946	EPSD	COSMIC	31.796	Down-regulation
AGC_DMPK_ROCK_ROCK1_ST	O60237	PPP1R12B	Q13464	ROCK1	T808	G809A	809	Missense	proximal	1	no	46.342	46.686	EPSD	COSMIC	31.796	Up-regulation
AGC_DMPK_ROCK_ROCK1_ST	O60237	PPP1R12B	Q13464	ROCK1	T808	W813S	813	Missense	distal	5	no	46.342	46.192	EPSD	COSMIC;CCLE	31.796	Down-regulation
AGC_DMPK_ROCK_ROCK1_ST	O60237	PPP1R12B	Q13464	ROCK1	S839	R833I	833	Missense	distal	-6	no	34.284	29.529	EPSD	COSMIC	31.796	Loss
AGC_DMPK_ROCK_ROCK1_ST	O60237	PPP1R12B	Q13464	ROCK1	S855	R857Q	857	Missense	proximal	2	no	33.364	32.209	EPSD	COSMIC	31.796	Down-regulation
AGC_DMPK_ROCK_ROCK1_ST	O60237	PPP1R12B	Q13464	ROCK1	S855	A858D	858	Missense	distal	3	no	33.364	33.314	EPSD	COSMIC	31.796	Down-regulation
AGC_DMPK_ROCK_ROCK1_ST	O60237	PPP1R12B	Q13464	ROCK1	S855	R853W	853	Missense	proximal	-2	no	33.364	32.279	EPSD	COSMIC	31.796	Down-regulation
AGC_DMPK_ROCK_ROCK1_ST	O60237	PPP1R12B	Q13464	ROCK1	S855	S855A	855	Missense	central	0	yes	33.364	0.000	EPSD	COSMIC	31.796	Loss
AGC_DMPK_ROCK_ROCK1_ST	O60237	PPP1R12B	Q13464	ROCK1	T869	R866C	866	Missense	distal	-3	no	40.474	15.190	EPSD	COSMIC	31.796	Loss
AGC_DMPK_ROCK_ROCK1_ST	O60237	PPP1R12B	Q13464	ROCK1	T869	T869A	869	Missense	central	0	yes	40.474	0.000	EPSD	COSMIC	31.796	Loss
AGC_DMPK_ROCK_ROCK1_ST	O60237	PPP1R12B	Q13464	ROCK1	S947	R944H	944	Missense	distal	-3	no	34.156	19.546	EPSD	COSMIC	31.796	Loss
AGC_DMPK_ROCK_ROCK1_ST	O60237	PPP1R12B	Q13464	ROCK1	S947	K945N	945	Missense	proximal	-2	no	34.156	31.618	EPSD	COSMIC;GDSC;CCLE	31.796	Loss
AGC_DMPK_ROCK_ROCK1_ST	O43293	DAPK3	Q13464	ROCK1	S50	R47H	47	Missense	distal	-3	no	48.189	33.578	EPSD	COSMIC	31.796	Down-regulation
AGC_DMPK_ROCK_ROCK1_ST	O43293	DAPK3	Q13464	ROCK1	S50	R54L	54	Missense	distal	4	no	48.189	46.178	EPSD	COSMIC	31.796	Down-regulation
AGC_DMPK_ROCK_ROCK1_ST	O43293	DAPK3	Q13464	ROCK1	S50	R53Q	53	Missense	distal	3	no	48.189	48.006	EPSD	COSMIC	31.796	Down-regulation
AGC_DMPK_ROCK_ROCK1_ST	O43293	DAPK3	Q13464	ROCK1	S50	F43L	43	Missense	distal	-7	no	48.189	48.320	EPSD	COSMIC	31.796	Up-regulation
AGC_DMPK_ROCK_ROCK1_ST	O43293	DAPK3	Q13464	ROCK1	S50	S57T	57	Missense	distal	7	no	48.189	48.570	EPSD	COSMIC	31.796	Up-regulation
AGC_DMPK_ROCK_ROCK1_ST	O43293	DAPK3	Q13464	ROCK1	T265	E271Q	271	Missense	distal	6	no	43.501	43.524	PhosphoSitePlus;EPSD	COSMIC	31.796	Up-regulation
AGC_DMPK_ROCK_ROCK1_ST	O43293	DAPK3	Q13464	ROCK1	T265	K258N	258	Missense	distal	-7	no	43.501	43.379	PhosphoSitePlus;EPSD	COSMIC	31.796	Down-regulation
AGC_DMPK_ROCK_ROCK1_ST	O43293	DAPK3	Q13464	ROCK1	T299	Y305C	305	Missense	distal	6	no	35.827	35.646	EPSD;PhosphoSitePlus	COSMIC;CCLE	31.796	Down-regulation
AGC_DMPK_ROCK_ROCK1_ST	O43293	DAPK3	Q13464	ROCK1	T299	R296C	296	Missense	distal	-3	no	35.827	10.542	EPSD;PhosphoSitePlus	COSMIC	31.796	Loss
AGC_DMPK_ROCK_ROCK1_ST	O43293	DAPK3	Q13464	ROCK1	T299	T300M	300	Missense	proximal	1	no	35.827	36.352	EPSD;PhosphoSitePlus	COSMIC;CCLE	31.796	Up-regulation
AGC_DMPK_ROCK_ROCK1_ST	O43293	DAPK3	Q13464	ROCK1	T299	R295L	295	Missense	distal	-4	no	35.827	32.069	EPSD;PhosphoSitePlus	COSMIC	31.796	Down-regulation
AGC_DMPK_ROCK_ROCK1_ST	O43293	DAPK3	Q13464	ROCK1	T299	Y305H	305	Missense	distal	6	no	35.827	35.391	EPSD;PhosphoSitePlus	COSMIC	31.796	Down-regulation
AGC_DMPK_ROCK_ROCK1_ST	O43293	DAPK3	Q13464	ROCK1	T300	Y305C	305	Missense	distal	5	no	33.498	33.711	EPSD	COSMIC;CCLE	31.796	Up-regulation
AGC_DMPK_ROCK_ROCK1_ST	O43293	DAPK3	Q13464	ROCK1	T300	R296C	296	Missense	distal	-4	no	33.498	28.328	EPSD	COSMIC	31.796	Loss
AGC_DMPK_ROCK_ROCK1_ST	O43293	DAPK3	Q13464	ROCK1	T300	T300M	300	Missense	central	0	yes	33.498	0.000	EPSD	COSMIC;CCLE	31.796	Loss
AGC_DMPK_ROCK_ROCK1_ST	O43293	DAPK3	Q13464	ROCK1	T300	R295L	295	Missense	distal	-5	no	33.498	30.574	EPSD	COSMIC	31.796	Loss
AGC_DMPK_ROCK_ROCK1_ST	O43293	DAPK3	Q13464	ROCK1	T300	Y305H	305	Missense	distal	5	no	33.498	33.080	EPSD	COSMIC	31.796	Down-regulation
AGC_DMPK_ROCK_ROCK1_ST	O43293	DAPK3	Q13464	ROCK1	S414	E421K	421	Missense	distal	7	no	32.611	32.046	EPSD	COSMIC	31.796	Down-regulation
AGC_DMPK_ROCK_ROCK1_ST	O43293	DAPK3	Q13464	ROCK1	S414	R419C	419	Missense	distal	5	no	32.611	33.583	EPSD	COSMIC	31.796	Up-regulation
AGC_DMPK_ROCK_ROCK1_ST	P08670	VIM	Q13464	ROCK1	S25	P18L	18	Missense	distal	-7	no	34.195	34.266	EPSD	COSMIC	31.796	Up-regulation
AGC_DMPK_ROCK_ROCK1_ST	P08670	VIM	Q13464	ROCK1	S25	S27R	27	Missense	proximal	2	no	34.195	35.060	EPSD	COSMIC	31.796	Up-regulation
AGC_DMPK_ROCK_ROCK1_ST	P08670	VIM	Q13464	ROCK1	S29	S27R	27	Missense	proximal	-2	no	27.085	40.086	EPSD	COSMIC	31.796	Gain
AGC_DMPK_ROCK_ROCK1_ST	P08670	VIM	Q13464	ROCK1	T32	R36H	36	Missense	distal	4	no	37.377	36.789	EPSD	COSMIC	31.796	Down-regulation
AGC_DMPK_ROCK_ROCK1_ST	P08670	VIM	Q13464	ROCK1	T32	S27R	27	Missense	distal	-5	no	37.377	39.650	EPSD	COSMIC	31.796	Up-regulation
AGC_DMPK_ROCK_ROCK1_ST	P08670	VIM	Q13464	ROCK1	T32	S34P	34	Missense	proximal	2	no	37.377	36.111	EPSD	COSMIC	31.796	Down-regulation
AGC_DMPK_ROCK_ROCK1_ST	P08670	VIM	Q13464	ROCK1	S47	S51N	51	Missense	distal	4	no	38.945	38.316	EPSD	COSMIC	31.796	Down-regulation
AGC_DMPK_ROCK_ROCK1_ST	P08670	VIM	Q13464	ROCK1	S66	R71Q	71	Missense	distal	5	no	31.514	32.353	EPSD	COSMIC	31.796	Gain
AGC_DMPK_ROCK_ROCK1_ST	P08670	VIM	Q13464	ROCK1	S72	R71Q	71	Missense	proximal	-1	no	36.246	34.029	PhosphoSitePlus	COSMIC	31.796	Down-regulation
AGC_DMPK_ROCK_ROCK1_ST	P08670	VIM	Q13464	ROCK1	S72	S65F	65	Missense	distal	-7	no	36.246	36.128	PhosphoSitePlus	COSMIC	31.796	Down-regulation
AGC_DMPK_ROCK_ROCK1_ST	P08670	VIM	Q13464	ROCK1	S72	V77L	77	Missense	distal	5	no	36.246	36.262	PhosphoSitePlus	COSMIC	31.796	Up-regulation
AGC_DMPK_ROCK_ROCK1_ST	P08670	VIM	Q13464	ROCK1	S72	R69C	69	Missense	distal	-3	no	36.246	10.961	PhosphoSitePlus	COSMIC	31.796	Loss
AGC_DMPK_ROCK_ROCK1_ST	P08670	VIM	Q13464	ROCK1	S278	V279M	279	Missense	proximal	1	no	40.007	39.914	EPSD	COSMIC;GDSC;CCLE	31.796	Down-regulation
AGC_DMPK_ROCK_ROCK1_ST	P08670	VIM	Q13464	ROCK1	S278	N283S	283	Missense	distal	5	no	40.007	39.883	EPSD	COSMIC	31.796	Down-regulation
AGC_DMPK_ROCK_ROCK1_ST	P08670	VIM	Q13464	ROCK1	S278	D271V	271	Missense	distal	-7	no	40.007	39.953	EPSD	COSMIC	31.796	Down-regulation
AGC_DMPK_ROCK_ROCK1_ST	P08670	VIM	Q13464	ROCK1	T426	E425K	425	Missense	proximal	-1	no	29.594	33.834	EPSD	COSMIC	31.796	Gain
AGC_DMPK_ROCK_ROCK1_ST	Q05397	PTK2	Q13464	ROCK1	T386	E380K	380	Missense	distal	-6	no	29.671	36.107	EPSD	COSMIC	31.796	Gain
AGC_DMPK_ROCK_ROCK1_ST	Q05397	PTK2	Q13464	ROCK1	T460	E466G	466	Missense	distal	6	no	32.181	32.161	EPSD	COSMIC	31.796	Down-regulation
AGC_DMPK_ROCK_ROCK1_ST	Q05397	PTK2	Q13464	ROCK1	S463	E466G	466	Missense	distal	3	no	32.060	32.265	EPSD	COSMIC	31.796	Up-regulation
AGC_DMPK_ROCK_ROCK1_ST	Q05397	PTK2	Q13464	ROCK1	S517	D519H	519	Missense	proximal	2	no	36.405	37.029	EPSD	COSMIC	31.796	Up-regulation
AGC_DMPK_ROCK_ROCK1_ST	Q05397	PTK2	Q13464	ROCK1	S517	S522C	522	Missense	distal	5	no	36.405	36.626	EPSD	COSMIC;GDSC;CCLE	31.796	Up-regulation
AGC_DMPK_ROCK_ROCK1_ST	Q05397	PTK2	Q13464	ROCK1	S580	A579V	579	Missense	proximal	-1	no	38.069	37.463	EPSD	COSMIC	31.796	Down-regulation
AGC_DMPK_ROCK_ROCK1_ST	Q05397	PTK2	Q13464	ROCK1	S695	R690L	690	Missense	distal	-5	no	36.717	33.793	EPSD	COSMIC	31.796	Down-regulation
AGC_DMPK_ROCK_ROCK1_ST	Q05397	PTK2	Q13464	ROCK1	S695	R692K	692	Missense	distal	-3	no	36.717	33.007	EPSD	COSMIC	31.796	Down-regulation
AGC_DMPK_ROCK_ROCK1_ST	Q05397	PTK2	Q13464	ROCK1	S695	T700M	700	Missense	distal	5	no	36.717	37.183	EPSD	COSMIC	31.796	Up-regulation
AGC_DMPK_ROCK_ROCK1_ST	Q05397	PTK2	Q13464	ROCK1	S708	G706R	706	Missense	proximal	-2	no	29.083	38.840	EPSD	COSMIC	31.796	Gain
AGC_DMPK_ROCK_ROCK1_ST	Q05397	PTK2	Q13464	ROCK1	S722	G728E	728	Missense	distal	6	no	36.463	36.483	EPSD	COSMIC	31.796	Up-regulation
AGC_DMPK_ROCK_ROCK1_ST	Q05397	PTK2	Q13464	ROCK1	S722	S722I	722	Missense	central	0	yes	36.463	0.000	EPSD	COSMIC	31.796	Loss
AGC_DMPK_ROCK_ROCK1_ST	Q05397	PTK2	Q13464	ROCK1	S732	G728E	728	Missense	distal	-4	no	33.230	31.716	PhosphoSitePlus	COSMIC	31.796	Loss
AGC_DMPK_ROCK_ROCK1_ST	Q05397	PTK2	Q13464	ROCK1	S840	R841L	841	Missense	proximal	1	no	32.355	33.738	EPSD	COSMIC	31.796	Up-regulation
AGC_DMPK_ROCK_ROCK1_ST	Q05397	PTK2	Q13464	ROCK1	T929	E926K	926	Missense	distal	-3	no	24.100	32.544	EPSD	COSMIC	31.796	Gain
AGC_DMPK_ROCK_ROCK1_ST	P53667	LIMK1	Q13464	ROCK1	S321	E322D	322	Missense	proximal	1	no	31.681	31.939	EPSD	COSMIC	31.796	Gain
AGC_DMPK_ROCK_ROCK1_ST	P53667	LIMK1	Q13464	ROCK1	S337	P336T	336	Missense	proximal	-1	no	30.417	31.858	EPSD	COSMIC	31.796	Gain
AGC_DMPK_ROCK_ROCK1_ST	P53667	LIMK1	Q13464	ROCK1	S439	S435I	435	Missense	distal	-4	no	39.623	39.588	EPSD	COSMIC	31.796	Down-regulation
AGC_DMPK_ROCK_ROCK1_ST	P48436	SOX9	Q13464	ROCK1	T52	E50K	50	Missense	proximal	-2	no	29.821	35.064	EPSD	COSMIC	31.796	Gain
AGC_DMPK_ROCK_ROCK1_ST	P48436	SOX9	Q13464	ROCK1	S64	P70S	70	Missense	distal	6	no	32.369	31.849	EPSD	COSMIC	31.796	Down-regulation
AGC_DMPK_ROCK_ROCK1_ST	P48436	SOX9	Q13464	ROCK1	S64	D67A	67	Missense	distal	3	no	32.369	32.419	EPSD	COSMIC	31.796	Up-regulation
AGC_DMPK_ROCK_ROCK1_ST	P48436	SOX9	Q13464	ROCK1	S64	D59Y	59	Missense	distal	-5	no	32.369	33.763	EPSD	COSMIC	31.796	Up-regulation
AGC_DMPK_ROCK_ROCK1_ST	P48436	SOX9	Q13464	ROCK1	S64	K68E	68	Missense	distal	4	no	32.369	30.438	EPSD	COSMIC	31.796	Loss
AGC_DMPK_ROCK_ROCK1_ST	P48436	SOX9	Q13464	ROCK1	S64	V71M	71	Missense	distal	7	no	32.369	32.277	EPSD	COSMIC	31.796	Down-regulation
AGC_DMPK_ROCK_ROCK1_ST	P48436	SOX9	Q13464	ROCK1	S64	P58S	58	Missense	distal	-6	no	32.369	35.093	EPSD	COSMIC	31.796	Up-regulation
AGC_DMPK_ROCK_ROCK1_ST	P48436	SOX9	Q13464	ROCK1	S64	E65A	65	Missense	proximal	1	no	32.369	32.268	EPSD	COSMIC	31.796	Down-regulation
AGC_DMPK_ROCK_ROCK1_ST	P48436	SOX9	Q13464	ROCK1	S64	S64R	64	Missense	central	0	yes	32.369	0.000	EPSD	COSMIC	31.796	Loss
AGC_DMPK_ROCK_ROCK1_ST	P48436	SOX9	Q13464	ROCK1	S64	D59N	59	Missense	distal	-5	no	32.369	33.136	EPSD	COSMIC	31.796	Up-regulation
AGC_DMPK_ROCK_ROCK1_ST	P48436	SOX9	Q13464	ROCK1	S181	K183N	183	Missense	proximal	2	no	49.170	47.173	PhosphoSitePlus	COSMIC	31.796	Down-regulation
AGC_DMPK_ROCK_ROCK1_ST	P48436	SOX9	Q13464	ROCK1	S231	G229R	229	Missense	proximal	-2	no	24.032	33.788	EPSD	COSMIC	31.796	Gain
AGC_DMPK_ROCK_ROCK1_ST	O14974	PPP1R12A	Q13464	ROCK1	T443	A448V	448	Missense	distal	5	no	37.502	38.047	EPSD	COSMIC	31.796	Up-regulation
AGC_DMPK_ROCK_ROCK1_ST	O14974	PPP1R12A	Q13464	ROCK1	S525	T524A	524	Missense	proximal	-1	no	35.425	34.373	EPSD	COSMIC;GDSC;CCLE	31.796	Down-regulation
AGC_DMPK_ROCK_ROCK1_ST	O14974	PPP1R12A	Q13464	ROCK1	T592	T590R	590	Missense	proximal	-2	no	18.621	31.894	EPSD	COSMIC	31.796	Gain
AGC_DMPK_ROCK_ROCK1_ST	O14974	PPP1R12A	Q13464	ROCK1	T593	T590R	590	Missense	distal	-3	no	27.531	35.061	EPSD	COSMIC	31.796	Gain
AGC_DMPK_ROCK_ROCK1_ST	O14974	PPP1R12A	Q13464	ROCK1	S668	R663I	663	Missense	distal	-5	no	39.953	37.695	EPSD	COSMIC	31.796	Down-regulation
AGC_DMPK_ROCK_ROCK1_ST	O14974	PPP1R12A	Q13464	ROCK1	S692	R694I	694	Missense	proximal	2	no	35.655	32.662	EPSD	COSMIC	31.796	Down-regulation
AGC_DMPK_ROCK_ROCK1_ST	O14974	PPP1R12A	Q13464	ROCK1	S695	R694I	694	Missense	proximal	-1	no	42.582	39.266	EPSD	COSMIC	31.796	Down-regulation
AGC_DMPK_ROCK_ROCK1_ST	O14974	PPP1R12A	Q13464	ROCK1	T696	R694I	694	Missense	proximal	-2	no	53.165	31.305	EPSD;PhosphoSitePlus	COSMIC	31.796	Loss
AGC_DMPK_ROCK_ROCK1_ST	O14974	PPP1R12A	Q13464	ROCK1	S852	R851H	851	Missense	proximal	-1	no	43.319	40.751	EPSD;PhosphoSitePlus	COSMIC	31.796	Down-regulation
AGC_DMPK_ROCK_ROCK1_ST	O14974	PPP1R12A	Q13464	ROCK1	S852	R851C	851	Missense	proximal	-1	no	43.319	39.038	EPSD;PhosphoSitePlus	COSMIC	31.796	Down-regulation
AGC_DMPK_ROCK_ROCK1_ST	O14974	PPP1R12A	Q13464	ROCK1	T853	R851H	851	Missense	proximal	-2	no	54.394	43.258	PhosphoSitePlus;EPSD	COSMIC	31.796	Down-regulation
AGC_DMPK_ROCK_ROCK1_ST	O14974	PPP1R12A	Q13464	ROCK1	T853	R851C	851	Missense	proximal	-2	no	54.394	21.535	PhosphoSitePlus;EPSD	COSMIC	31.796	Loss
AGC_DMPK_ROCK_ROCK1_ST	O14974	PPP1R12A	Q13464	ROCK1	T892	G898D	898	Missense	distal	6	no	40.198	40.399	EPSD	COSMIC	31.796	Up-regulation
AGC_DMPK_ROCK_ROCK1_ST	O14974	PPP1R12A	Q13464	ROCK1	T892	R889G	889	Missense	distal	-3	no	40.198	30.008	EPSD	COSMIC	31.796	Loss
AGC_DMPK_ROCK_ROCK1_ST	O14974	PPP1R12A	Q13464	ROCK1	T892	S888F	888	Missense	distal	-4	no	40.198	38.172	EPSD	COSMIC	31.796	Down-regulation
AGC_DMPK_ROCK_ROCK1_ST	O14974	PPP1R12A	Q13464	ROCK1	S903	G898D	898	Missense	distal	-5	no	33.551	32.860	EPSD	COSMIC	31.796	Down-regulation
AGC_DMPK_ROCK_ROCK1_ST	O14974	PPP1R12A	Q13464	ROCK1	S903	S910T	910	Missense	distal	7	no	33.551	33.932	EPSD	COSMIC	31.796	Up-regulation
AGC_DMPK_ROCK_ROCK1_ST	Q9UPT6	MAPK8IP3	Q13464	ROCK1	T169	R167Q	167	Missense	proximal	-2	no	32.946	19.776	EPSD	COSMIC	31.796	Loss
AGC_DMPK_ROCK_ROCK1_ST	Q9UPT6	MAPK8IP3	Q13464	ROCK1	T169	V176M	176	Missense	distal	7	no	32.946	32.854	EPSD	COSMIC	31.796	Down-regulation
AGC_DMPK_ROCK_ROCK1_ST	Q9UPT6	MAPK8IP3	Q13464	ROCK1	T169	R167W	167	Missense	proximal	-2	no	32.946	31.860	EPSD	COSMIC	31.796	Down-regulation
AGC_DMPK_ROCK_ROCK1_ST	Q9UPT6	MAPK8IP3	Q13464	ROCK1	S191	G188R	188	Missense	distal	-3	no	26.252	36.443	EPSD	COSMIC	31.796	Gain
AGC_DMPK_ROCK_ROCK1_ST	Q9UPT6	MAPK8IP3	Q13464	ROCK1	T275	S279F	279	Missense	distal	4	no	35.212	33.674	EPSD	COSMIC	31.796	Down-regulation
AGC_DMPK_ROCK_ROCK1_ST	Q9UPT6	MAPK8IP3	Q13464	ROCK1	S314	R307C	307	Missense	distal	-7	no	41.971	41.718	PhosphoSitePlus;EPSD	COSMIC;GDSC;CCLE	31.796	Down-regulation
AGC_DMPK_ROCK_ROCK1_ST	Q9UPT6	MAPK8IP3	Q13464	ROCK1	S314	R315C	315	Missense	proximal	1	no	41.971	42.767	PhosphoSitePlus;EPSD	COSMIC;CCLE	31.796	Up-regulation
AGC_DMPK_ROCK_ROCK1_ST	Q9UPT6	MAPK8IP3	Q13464	ROCK1	S314	R312H	312	Missense	proximal	-2	no	41.971	30.835	PhosphoSitePlus;EPSD	COSMIC	31.796	Loss
AGC_DMPK_ROCK_ROCK1_ST	Q9UPT6	MAPK8IP3	Q13464	ROCK1	S314	R312C	312	Missense	proximal	-2	no	41.971	9.113	PhosphoSitePlus;EPSD	COSMIC	31.796	Loss
AGC_DMPK_ROCK_ROCK1_ST	Q9UPT6	MAPK8IP3	Q13464	ROCK1	S314	S314I	314	Missense	central	0	yes	41.971	0.000	PhosphoSitePlus;EPSD	COSMIC	31.796	Loss
AGC_DMPK_ROCK_ROCK1_ST	Q9UPT6	MAPK8IP3	Q13464	ROCK1	S364	Q368K	368	Missense	distal	4	no	37.309	38.787	EPSD;PhosphoSitePlus	COSMIC	31.796	Up-regulation
AGC_DMPK_ROCK_ROCK1_ST	Q9UPT6	MAPK8IP3	Q13464	ROCK1	S364	R361H	361	Missense	distal	-3	no	37.309	22.698	EPSD;PhosphoSitePlus	COSMIC;GDSC	31.796	Loss
AGC_DMPK_ROCK_ROCK1_ST	Q9UPT6	MAPK8IP3	Q13464	ROCK1	S365	Q368K	368	Missense	distal	3	no	34.517	34.725	EPSD;PhosphoSitePlus	COSMIC	31.796	Up-regulation
AGC_DMPK_ROCK_ROCK1_ST	Q9UPT6	MAPK8IP3	Q13464	ROCK1	S365	R361H	361	Missense	distal	-4	no	34.517	31.536	EPSD;PhosphoSitePlus	COSMIC;GDSC	31.796	Loss
AGC_DMPK_ROCK_ROCK1_ST	Q9UPT6	MAPK8IP3	Q13464	ROCK1	T552	A557V	557	Missense	distal	5	no	38.740	39.284	EPSD	COSMIC	31.796	Up-regulation
AGC_DMPK_ROCK_ROCK1_ST	Q9UPT6	MAPK8IP3	Q13464	ROCK1	T552	T552I	552	Missense	central	0	yes	38.740	0.000	EPSD	COSMIC;CCLE	31.796	Loss
AGC_DMPK_ROCK_ROCK1_ST	Q9UPT6	MAPK8IP3	Q13464	ROCK1	S595	P592L	592	Missense	distal	-3	no	25.525	31.823	EPSD	COSMIC	31.796	Gain
AGC_DMPK_ROCK_ROCK1_ST	Q9UPT6	MAPK8IP3	Q13464	ROCK1	S602	H599Y	599	Missense	distal	-3	no	30.532	39.728	EPSD	COSMIC	31.796	Gain
AGC_DMPK_ROCK_ROCK1_ST	Q9UPT6	MAPK8IP3	Q13464	ROCK1	S1191	A1198T	1198	Missense	distal	7	no	33.950	34.488	EPSD	COSMIC;GDSC;CCLE	31.796	Up-regulation
AGC_PKG_PRKG2_ST	P29474	NOS3	Q13237	PRKG2	T495	G489S	489	Missense	distal	-6	no	68.880	69.949	PhosphoSitePlus;EPSD	COSMIC	42.682	Up-regulation
AGC_PKG_PRKG2_ST	P29474	NOS3	Q13237	PRKG2	T495	G489D	489	Missense	distal	-6	no	68.880	69.584	PhosphoSitePlus;EPSD	COSMIC	42.682	Up-regulation
AGC_PKG_PRKG2_ST	P29474	NOS3	Q13237	PRKG2	S615	K610Q	610	Missense	distal	-5	no	44.807	44.850	EPSD	COSMIC	42.682	Up-regulation
AGC_PKG_PRKG2_ST	P29474	NOS3	Q13237	PRKG2	S633	D637H	637	Missense	distal	4	no	74.934	70.955	EPSD;PhosphoSitePlus	COSMIC	42.682	Down-regulation
AGC_PKG_PRKG2_ST	P29474	NOS3	Q13237	PRKG2	S633	N635T	635	Missense	proximal	2	no	74.934	75.054	EPSD;PhosphoSitePlus	COSMIC	42.682	Up-regulation
AGC_PKG_PRKG2_ST	P04626	ERBB2	Q13237	PRKG2	T686	R683G	683	Missense	distal	-3	no	64.945	45.963	PhosphoSitePlus	COSMIC	42.682	Down-regulation
AGC_PKG_PRKG2_ST	P04626	ERBB2	Q13237	PRKG2	T686	R683Q	683	Missense	distal	-3	no	64.945	48.741	PhosphoSitePlus	COSMIC	42.682	Down-regulation
AGC_PKG_PRKG2_ST	P04626	ERBB2	Q13237	PRKG2	T686	R688W	688	Missense	proximal	2	no	64.945	65.095	PhosphoSitePlus	COSMIC	42.682	Up-regulation
AGC_PKG_PRKG2_ST	P04626	ERBB2	Q13237	PRKG2	T686	Q680H	680	Missense	distal	-6	no	64.945	62.267	PhosphoSitePlus	COSMIC	42.682	Down-regulation
AGC_PKG_PRKG2_ST	P04626	ERBB2	Q13237	PRKG2	T686	Q679L	679	Missense	distal	-7	no	64.945	65.183	PhosphoSitePlus	COSMIC	42.682	Up-regulation
AGC_PKG_PRKG2_ST	P04626	ERBB2	Q13237	PRKG2	T686	E693K	693	Missense	distal	7	no	64.945	65.321	PhosphoSitePlus	COSMIC	42.682	Up-regulation
AGC_PKG_PRKG2_ST	P04626	ERBB2	Q13237	PRKG2	T686	T686R	686	Missense	central	0	yes	64.945	0.000	PhosphoSitePlus	COSMIC;CCLE	42.682	Loss
AGC_PKG_PRKG2_ST	P04626	ERBB2	Q13237	PRKG2	T686	L690P	690	Missense	distal	4	no	64.945	68.860	PhosphoSitePlus	COSMIC	42.682	Up-regulation
AGC_PKG_PRKG2_ST	P04626	ERBB2	Q13237	PRKG2	T686	R683W	683	Missense	distal	-3	no	64.945	31.297	PhosphoSitePlus	COSMIC	42.682	Loss
AGC_PKG_PRKG2_ST	P04626	ERBB2	Q13237	PRKG2	T759	E757K	757	Missense	proximal	-2	no	42.419	72.781	EPSD	COSMIC	42.682	Gain
AGC_PKG_PRKG2_ST	P04626	ERBB2	Q13237	PRKG2	T759	E757D	757	Missense	proximal	-2	no	42.419	49.249	EPSD	COSMIC	42.682	Gain
AGC_PKG_PRKG2_ST	P04626	ERBB2	Q13237	PRKG2	S760	E757K	757	Missense	distal	-3	no	30.049	50.874	EPSD	COSMIC	42.682	Gain
AGC_PKG_PRKG2_ST	P04626	ERBB2	Q13237	PRKG2	S819	R816C	816	Missense	distal	-3	no	49.056	10.533	EPSD	COSMIC	42.682	Loss
AGC_PKG_PRKG2_ST	P04626	ERBB2	Q13237	PRKG2	S819	S819F	819	Missense	central	0	yes	49.056	0.000	EPSD	COSMIC	42.682	Loss
AGC_PKG_PRKG2_ST	P04626	ERBB2	Q13237	PRKG2	S819	G815R	815	Missense	distal	-4	no	49.056	48.053	EPSD	COSMIC	42.682	Down-regulation
AGC_PKG_PRKG2_ST	P04626	ERBB2	Q13237	PRKG2	S819	N813I	813	Missense	distal	-6	no	49.056	48.960	EPSD	COSMIC	42.682	Down-regulation
AGC_PKG_PRKG2_ST	P04626	ERBB2	Q13237	PRKG2	S819	D821Y	821	Missense	proximal	2	no	49.056	49.024	EPSD	COSMIC	42.682	Down-regulation
AGC_PKG_PRKG2_ST	P04626	ERBB2	Q13237	PRKG2	S819	R814C	814	Missense	distal	-5	no	49.056	49.075	EPSD	COSMIC	42.682	Up-regulation
AGC_PKG_PRKG2_ST	P04626	ERBB2	Q13237	PRKG2	S819	R816H	816	Missense	distal	-3	no	49.056	35.240	EPSD	COSMIC;GDSC;CCLE	42.682	Loss
AGC_PKG_PRKG2_ST	P04626	ERBB2	Q13237	PRKG2	S819	S819P	819	Missense	central	0	yes	49.056	0.000	EPSD	COSMIC	42.682	Loss
AGC_PKG_PRKG2_ST	P04626	ERBB2	Q13237	PRKG2	T900	R896C	896	Missense	distal	-4	no	58.632	59.564	EPSD	COSMIC	42.682	Up-regulation
AGC_PKG_PRKG2_ST	P04626	ERBB2	Q13237	PRKG2	T900	W906C	906	Missense	distal	6	no	58.632	58.307	EPSD	COSMIC	42.682	Down-regulation
AGC_PKG_PRKG2_ST	P04626	ERBB2	Q13237	PRKG2	T900	Q902H	902	Missense	proximal	2	no	58.632	58.842	EPSD	COSMIC	42.682	Up-regulation
AGC_PKG_PRKG2_ST	P04626	ERBB2	Q13237	PRKG2	T900	F899L	899	Missense	proximal	-1	no	58.632	58.493	EPSD	COSMIC	42.682	Down-regulation
AGC_PKG_PRKG2_ST	P04626	ERBB2	Q13237	PRKG2	T900	R897W	897	Missense	distal	-3	no	58.632	24.984	EPSD	COSMIC	42.682	Loss
AGC_PKG_PRKG2_ST	P04626	ERBB2	Q13237	PRKG2	T900	I894L	894	Missense	distal	-6	no	58.632	55.796	EPSD	COSMIC	42.682	Down-regulation
AGC_PKG_PRKG2_ST	P04626	ERBB2	Q13237	PRKG2	T900	R896H	896	Missense	distal	-4	no	58.632	60.750	EPSD	COSMIC;CCLE	42.682	Up-regulation
AGC_PKG_PRKG2_ST	P04626	ERBB2	Q13237	PRKG2	T900	R897G	897	Missense	distal	-3	no	58.632	39.650	EPSD	COSMIC	42.682	Loss
AGC_PKG_PRKG2_ST	P04626	ERBB2	Q13237	PRKG2	T900	L895F	895	Missense	distal	-5	no	58.632	58.599	EPSD	COSMIC	42.682	Down-regulation
AGC_PKG_PRKG2_ST	P04626	ERBB2	Q13237	PRKG2	S1049	S1049I	1049	Missense	central	0	yes	61.155	0.000	EPSD	COSMIC	42.682	Loss
AGC_PKG_PRKG2_ST	P04626	ERBB2	Q13237	PRKG2	S1049	S1051F	1051	Missense	proximal	2	no	61.155	61.328	EPSD	COSMIC	42.682	Up-regulation
AGC_PKG_PRKG2_ST	P04626	ERBB2	Q13237	PRKG2	S1049	S1050L	1050	Missense	proximal	1	no	61.155	59.756	EPSD	COSMIC;GDSC	42.682	Down-regulation
AGC_PKG_PRKG2_ST	P04626	ERBB2	Q13237	PRKG2	S1049	G1056S	1056	Missense	distal	7	no	61.155	62.354	EPSD	COSMIC	42.682	Up-regulation
AGC_PKG_PRKG2_ST	P04626	ERBB2	Q13237	PRKG2	S1049	G1056D	1056	Missense	distal	7	no	61.155	61.556	EPSD	COSMIC	42.682	Up-regulation
AGC_PKG_PRKG2_ST	P04626	ERBB2	Q13237	PRKG2	S1049	G1056C	1056	Missense	distal	7	no	61.155	61.152	EPSD	COSMIC	42.682	Down-regulation
AGC_PKG_PRKG2_ST	P04626	ERBB2	Q13237	PRKG2	S1050	S1049I	1049	Missense	proximal	-1	no	61.015	60.306	EPSD	COSMIC	42.682	Down-regulation
AGC_PKG_PRKG2_ST	P04626	ERBB2	Q13237	PRKG2	S1050	S1051F	1051	Missense	proximal	1	no	61.015	60.534	EPSD	COSMIC	42.682	Down-regulation
AGC_PKG_PRKG2_ST	P04626	ERBB2	Q13237	PRKG2	S1050	S1050L	1050	Missense	central	0	yes	61.015	0.000	EPSD	COSMIC;GDSC	42.682	Loss
AGC_PKG_PRKG2_ST	P04626	ERBB2	Q13237	PRKG2	S1050	G1056S	1056	Missense	distal	6	no	61.015	60.394	EPSD	COSMIC	42.682	Down-regulation
AGC_PKG_PRKG2_ST	P04626	ERBB2	Q13237	PRKG2	S1050	G1056D	1056	Missense	distal	6	no	61.015	61.204	EPSD	COSMIC	42.682	Up-regulation
AGC_PKG_PRKG2_ST	P04626	ERBB2	Q13237	PRKG2	S1050	G1056C	1056	Missense	distal	6	no	61.015	60.888	EPSD	COSMIC	42.682	Down-regulation
AGC_PKG_PRKG2_ST	P04626	ERBB2	Q13237	PRKG2	S1051	S1049I	1049	Missense	proximal	-2	no	44.772	36.718	EPSD	COSMIC	42.682	Loss
AGC_PKG_PRKG2_ST	P04626	ERBB2	Q13237	PRKG2	S1051	S1051F	1051	Missense	central	0	yes	44.772	0.000	EPSD	COSMIC	42.682	Loss
AGC_PKG_PRKG2_ST	P04626	ERBB2	Q13237	PRKG2	S1051	S1050L	1050	Missense	proximal	-1	no	44.772	44.416	EPSD	COSMIC;GDSC	42.682	Down-regulation
AGC_PKG_PRKG2_ST	P04626	ERBB2	Q13237	PRKG2	S1051	D1058A	1058	Missense	distal	7	no	44.772	44.605	EPSD	COSMIC	42.682	Down-regulation
AGC_PKG_PRKG2_ST	P04626	ERBB2	Q13237	PRKG2	S1051	D1058N	1058	Missense	distal	7	no	44.772	44.957	EPSD	COSMIC	42.682	Up-regulation
AGC_PKG_PRKG2_ST	P04626	ERBB2	Q13237	PRKG2	S1051	G1056S	1056	Missense	distal	5	no	44.772	45.276	EPSD	COSMIC	42.682	Up-regulation
AGC_PKG_PRKG2_ST	P04626	ERBB2	Q13237	PRKG2	S1051	G1056D	1056	Missense	distal	5	no	44.772	45.317	EPSD	COSMIC	42.682	Up-regulation
AGC_PKG_PRKG2_ST	P04626	ERBB2	Q13237	PRKG2	S1051	G1056C	1056	Missense	distal	5	no	44.772	44.687	EPSD	COSMIC	42.682	Down-regulation
AGC_PKG_PRKG2_ST	P04626	ERBB2	Q13237	PRKG2	T1052	S1050L	1050	Missense	proximal	-2	no	33.956	47.711	EPSD	COSMIC;GDSC	42.682	Gain
AGC_PKG_PRKG2_ST	P04626	ERBB2	Q13237	PRKG2	S1054	S1049I	1049	Missense	distal	-5	no	49.219	49.269	EPSD	COSMIC	42.682	Up-regulation
AGC_PKG_PRKG2_ST	P04626	ERBB2	Q13237	PRKG2	S1054	S1051F	1051	Missense	distal	-3	no	49.219	33.464	EPSD	COSMIC	42.682	Loss
AGC_PKG_PRKG2_ST	P04626	ERBB2	Q13237	PRKG2	S1054	S1050L	1050	Missense	distal	-4	no	49.219	51.174	EPSD	COSMIC;GDSC	42.682	Up-regulation
AGC_PKG_PRKG2_ST	P04626	ERBB2	Q13237	PRKG2	S1054	D1058A	1058	Missense	distal	4	no	49.219	50.455	EPSD	COSMIC	42.682	Up-regulation
AGC_PKG_PRKG2_ST	P04626	ERBB2	Q13237	PRKG2	S1054	D1058N	1058	Missense	distal	4	no	49.219	48.946	EPSD	COSMIC	42.682	Down-regulation
AGC_PKG_PRKG2_ST	P04626	ERBB2	Q13237	PRKG2	S1054	G1056S	1056	Missense	proximal	2	no	49.219	48.966	EPSD	COSMIC	42.682	Down-regulation
AGC_PKG_PRKG2_ST	P04626	ERBB2	Q13237	PRKG2	S1054	G1056D	1056	Missense	proximal	2	no	49.219	49.130	EPSD	COSMIC	42.682	Down-regulation
AGC_PKG_PRKG2_ST	P04626	ERBB2	Q13237	PRKG2	S1054	L1061P	1061	Missense	distal	7	no	49.219	50.523	EPSD	COSMIC	42.682	Up-regulation
AGC_PKG_PRKG2_ST	P04626	ERBB2	Q13237	PRKG2	S1054	G1056C	1056	Missense	proximal	2	no	49.219	49.106	EPSD	COSMIC	42.682	Down-regulation
AGC_PKG_PRKG2_ST	P04626	ERBB2	Q13237	PRKG2	S1066	E1064K	1064	Missense	proximal	-2	no	36.446	66.809	EPSD	COSMIC	42.682	Gain
AGC_PKG_PRKG2_ST	P04626	ERBB2	Q13237	PRKG2	S1113	S1107N	1107	Missense	distal	-6	no	57.408	55.075	EPSD	COSMIC	42.682	Down-regulation
AGC_PKG_PRKG2_ST	P04626	ERBB2	Q13237	PRKG2	S1113	P1116S	1116	Missense	distal	3	no	57.408	57.935	EPSD	COSMIC	42.682	Up-regulation
AGC_PKG_PRKG2_ST	P04626	ERBB2	Q13237	PRKG2	S1113	E1114G	1114	Missense	proximal	1	no	57.408	56.780	EPSD	COSMIC	42.682	Down-regulation
AGC_PKG_PRKG2_ST	P04626	ERBB2	Q13237	PRKG2	S1113	R1111Q	1111	Missense	proximal	-2	no	57.408	42.394	EPSD	COSMIC	42.682	Loss
AGC_PKG_PRKG2_ST	P04626	ERBB2	Q13237	PRKG2	S1113	E1114Q	1114	Missense	proximal	1	no	57.408	57.250	EPSD	COSMIC	42.682	Down-regulation
AGC_PKG_PRKG2_ST	P04626	ERBB2	Q13237	PRKG2	S1174	L1167F	1167	Missense	distal	-7	no	52.567	50.412	EPSD	COSMIC	42.682	Down-regulation
AGC_PKG_PRKG2_ST	P04626	ERBB2	Q13237	PRKG2	S1174	L1173P	1173	Missense	proximal	-1	no	52.567	53.137	EPSD	COSMIC	42.682	Up-regulation
AGC_PKG_PRKG2_ST	P04626	ERBB2	Q13237	PRKG2	S1174	S1174F	1174	Missense	central	0	yes	52.567	0.000	EPSD	COSMIC	42.682	Loss
AGC_PKG_PRKG2_ST	P04626	ERBB2	Q13237	PRKG2	S1174	P1170A	1170	Missense	distal	-4	no	52.567	51.040	EPSD	COSMIC	42.682	Down-regulation
AGC_PKG_PRKG2_ST	P04626	ERBB2	Q13237	PRKG2	S1174	G1176W	1176	Missense	proximal	2	no	52.567	52.465	EPSD	COSMIC	42.682	Down-regulation
AGC_PKG_PRKG2_ST	P04626	ERBB2	Q13237	PRKG2	S1174	K1171M	1171	Missense	distal	-3	no	52.567	31.043	EPSD	COSMIC	42.682	Loss
AGC_PKG_PRKG2_ST	P04626	ERBB2	Q13237	PRKG2	S1174	P1175R	1175	Missense	proximal	1	no	52.567	53.286	EPSD	COSMIC	42.682	Up-regulation
AGC_PKG_PRKG2_ST	P04626	ERBB2	Q13237	PRKG2	S1174	K1177E	1177	Missense	distal	3	no	52.567	52.506	EPSD	COSMIC	42.682	Down-regulation
AGC_PKG_PRKG2_ST	P04626	ERBB2	Q13237	PRKG2	S1174	L1167V	1167	Missense	distal	-7	no	52.567	50.249	EPSD	COSMIC	42.682	Down-regulation
AGC_PKG_PRKG2_ST	P04626	ERBB2	Q13237	PRKG2	S1235	P1233L	1233	Missense	proximal	-2	no	29.933	46.913	EPSD	COSMIC	42.682	Gain
AGC_PKG_PRKG2_ST	P29350	PTPN6	Q13237	PRKG2	S10	R7Q	7	Missense	distal	-3	no	48.068	31.864	EPSD	COSMIC	42.682	Loss
AGC_PKG_PRKG2_ST	P29350	PTPN6	Q13237	PRKG2	S10	T16I	16	Missense	distal	6	no	48.068	48.732	EPSD	COSMIC	42.682	Up-regulation
AGC_PKG_PRKG2_ST	P29350	PTPN6	Q13237	PRKG2	S10	D13Y	13	Missense	distal	3	no	48.068	47.525	EPSD	COSMIC	42.682	Down-regulation
AGC_PKG_PRKG2_ST	P29350	PTPN6	Q13237	PRKG2	S10	F5L	5	Missense	distal	-5	no	48.068	48.101	EPSD	COSMIC	42.682	Up-regulation
AGC_PKG_PRKG2_ST	P29350	PTPN6	Q13237	PRKG2	S10	D8Y	8	Missense	proximal	-2	no	48.068	40.817	EPSD	COSMIC;GDSC;CCLE	42.682	Loss
AGC_PKG_PRKG2_ST	P29350	PTPN6	Q13237	PRKG2	S10	L17M	17	Missense	distal	7	no	48.068	48.846	EPSD	COSMIC	42.682	Up-regulation
AGC_PKG_PRKG2_ST	P29350	PTPN6	Q13237	PRKG2	S32	G25C	25	Missense	distal	-7	no	62.940	62.465	EPSD	COSMIC	42.682	Down-regulation
AGC_PKG_PRKG2_ST	P29350	PTPN6	Q13237	PRKG2	S32	R33G	33	Missense	proximal	1	no	62.940	61.687	EPSD	COSMIC	42.682	Down-regulation
AGC_PKG_PRKG2_ST	P29350	PTPN6	Q13237	PRKG2	S32	R30W	30	Missense	proximal	-2	no	62.940	29.590	EPSD	COSMIC	42.682	Loss
AGC_PKG_PRKG2_ST	P29350	PTPN6	Q13237	PRKG2	S32	S32N	32	Missense	central	0	yes	62.940	0.000	EPSD	COSMIC	42.682	Loss
AGC_PKG_PRKG2_ST	P29350	PTPN6	Q13237	PRKG2	T462	D467H	467	Missense	distal	5	no	43.545	42.868	EPSD	COSMIC	42.682	Down-regulation
AGC_PKG_PRKG2_ST	P29350	PTPN6	Q13237	PRKG2	T462	M468V	468	Missense	distal	6	no	43.545	43.402	EPSD	COSMIC	42.682	Down-regulation
AGC_PKG_PRKG2_ST	P29350	PTPN6	Q13237	PRKG2	S534	E535G	535	Missense	proximal	1	no	52.871	52.244	EPSD	COSMIC	42.682	Down-regulation
AGC_PKG_PRKG2_ST	P29350	PTPN6	Q13237	PRKG2	S534	S528L	528	Missense	distal	-6	no	52.871	47.606	EPSD	COSMIC	42.682	Down-regulation
AGC_PKG_PRKG2_ST	P29350	PTPN6	Q13237	PRKG2	S534	S528P	528	Missense	distal	-6	no	52.871	48.776	EPSD	COSMIC	42.682	Down-regulation
AGC_PKG_PRKG2_ST	P29350	PTPN6	Q13237	PRKG2	S534	G537R	537	Missense	distal	3	no	52.871	52.910	EPSD	COSMIC	42.682	Up-regulation
AGC_PKG_PRKG2_ST	P29350	PTPN6	Q13237	PRKG2	T540	E535G	535	Missense	distal	-5	no	44.587	44.588	EPSD	COSMIC	42.682	Up-regulation
AGC_PKG_PRKG2_ST	P29350	PTPN6	Q13237	PRKG2	T540	A544T	544	Missense	distal	4	no	44.587	43.383	EPSD	COSMIC	42.682	Down-regulation
AGC_PKG_PRKG2_ST	P29350	PTPN6	Q13237	PRKG2	T540	M545R	545	Missense	distal	5	no	44.587	44.954	EPSD	COSMIC	42.682	Up-regulation
AGC_PKG_PRKG2_ST	P29350	PTPN6	Q13237	PRKG2	T540	G537R	537	Missense	distal	-3	no	44.587	63.569	EPSD	COSMIC	42.682	Up-regulation
AGC_PKG_PRKG2_ST	P29350	PTPN6	Q13237	PRKG2	S553	R554S	554	Missense	proximal	1	no	84.676	84.787	EPSD;PhosphoSitePlus	COSMIC	42.682	Up-regulation
AGC_PKG_PRKG2_ST	P29350	PTPN6	Q13237	PRKG2	S553	R554C	554	Missense	proximal	1	no	84.676	84.006	EPSD;PhosphoSitePlus	COSMIC	42.682	Down-regulation
AGC_PKG_PRKG2_ST	P29350	PTPN6	Q13237	PRKG2	S553	R554H	554	Missense	proximal	1	no	84.676	82.478	EPSD;PhosphoSitePlus	COSMIC;GDSC	42.682	Down-regulation
AGC_PKG_PRKG2_ST	P29350	PTPN6	Q13237	PRKG2	S556	R554S	554	Missense	proximal	-2	no	50.092	24.259	PhosphoSitePlus;EPSD	COSMIC	42.682	Loss
AGC_PKG_PRKG2_ST	P29350	PTPN6	Q13237	PRKG2	S556	R554C	554	Missense	proximal	-2	no	50.092	16.001	PhosphoSitePlus;EPSD	COSMIC	42.682	Loss
AGC_PKG_PRKG2_ST	P29350	PTPN6	Q13237	PRKG2	S556	R554H	554	Missense	proximal	-2	no	50.092	34.853	PhosphoSitePlus;EPSD	COSMIC;GDSC	42.682	Loss
AGC_PKG_PRKG2_ST	P29350	PTPN6	Q13237	PRKG2	S557	R554S	554	Missense	distal	-3	no	48.590	34.670	EPSD;PhosphoSitePlus	COSMIC	42.682	Loss
AGC_PKG_PRKG2_ST	P29350	PTPN6	Q13237	PRKG2	S557	R554C	554	Missense	distal	-3	no	48.590	10.067	EPSD;PhosphoSitePlus	COSMIC	42.682	Loss
AGC_PKG_PRKG2_ST	P29350	PTPN6	Q13237	PRKG2	S557	R554H	554	Missense	distal	-3	no	48.590	34.774	EPSD;PhosphoSitePlus	COSMIC;GDSC	42.682	Loss
AGC_PKG_PRKG2_ST	P09619	PDGFRB	Q13237	PRKG2	S643	A647S	647	Missense	distal	4	no	63.535	64.591	EPSD	COSMIC	42.682	Up-regulation
AGC_PKG_PRKG2_ST	P09619	PDGFRB	Q13237	PRKG2	S643	S642G	642	Missense	proximal	-1	no	63.535	63.281	EPSD	COSMIC	42.682	Down-regulation
AGC_PKG_PRKG2_ST	P09619	PDGFRB	Q13237	PRKG2	S643	R641H	641	Missense	proximal	-2	no	63.535	48.295	EPSD	COSMIC	42.682	Down-regulation
AGC_PKG_PRKG2_ST	P09619	PDGFRB	Q13237	PRKG2	S643	K645T	645	Missense	proximal	2	no	63.535	63.732	EPSD	COSMIC	42.682	Up-regulation
AGC_PKG_PRKG2_ST	P09619	PDGFRB	Q13237	PRKG2	S643	Q646H	646	Missense	distal	3	no	63.535	63.101	EPSD	COSMIC	42.682	Down-regulation
AGC_PKG_PRKG2_ST	P09619	PDGFRB	Q13237	PRKG2	S643	S650P	650	Missense	distal	7	no	63.535	62.919	EPSD	COSMIC;CCLE	42.682	Down-regulation
AGC_PKG_PRKG2_ST	P09619	PDGFRB	Q13237	PRKG2	S705	F700V	700	Missense	distal	-5	no	53.834	53.836	EPSD	COSMIC	42.682	Up-regulation
AGC_PKG_PRKG2_ST	P09619	PDGFRB	Q13237	PRKG2	S705	L701Q	701	Missense	distal	-4	no	53.834	54.525	EPSD	COSMIC	42.682	Up-regulation
AGC_PKG_PRKG2_ST	P09619	PDGFRB	Q13237	PRKG2	S705	P710L	710	Missense	distal	5	no	53.834	53.551	EPSD	COSMIC	42.682	Down-regulation
AGC_PKG_PRKG2_ST	P09619	PDGFRB	Q13237	PRKG2	S705	D706N	706	Missense	proximal	1	no	53.834	54.574	EPSD	COSMIC;GDSC;CCLE	42.682	Up-regulation
AGC_PKG_PRKG2_ST	P09619	PDGFRB	Q13237	PRKG2	S705	P711S	711	Missense	distal	6	no	53.834	53.117	EPSD	COSMIC	42.682	Down-regulation
AGC_PKG_PRKG2_ST	P09619	PDGFRB	Q13237	PRKG2	S705	H698Q	698	Missense	distal	-7	no	53.834	52.948	EPSD	COSMIC	42.682	Down-regulation
AGC_PKG_PRKG2_ST	P09619	PDGFRB	Q13237	PRKG2	S705	R709H	709	Missense	distal	4	no	53.834	51.301	EPSD	COSMIC	42.682	Down-regulation
AGC_PKG_PRKG2_ST	P09619	PDGFRB	Q13237	PRKG2	S705	S705F	705	Missense	central	0	yes	53.834	0.000	EPSD	COSMIC	42.682	Loss
AGC_PKG_PRKG2_ST	P09619	PDGFRB	Q13237	PRKG2	S712	P710L	710	Missense	proximal	-2	no	37.989	54.970	PhosphoSitePlus	COSMIC	42.682	Gain
AGC_PKG_PRKG2_ST	P09619	PDGFRB	Q13237	PRKG2	S748	D742N	742	Missense	distal	-6	no	46.193	44.226	EPSD	COSMIC	42.682	Down-regulation
AGC_PKG_PRKG2_ST	P09619	PDGFRB	Q13237	PRKG2	S748	P753T	753	Missense	distal	5	no	46.193	46.451	EPSD	COSMIC;GDSC;CCLE	42.682	Up-regulation
AGC_PKG_PRKG2_ST	Q14847	LASP1	Q13237	PRKG2	S61	A55T	55	Missense	distal	-6	no	45.490	44.844	EPSD	COSMIC	42.682	Down-regulation
AGC_PKG_PRKG2_ST	Q14847	LASP1	Q13237	PRKG2	S61	M64L	64	Missense	distal	3	no	45.490	45.309	EPSD	COSMIC	42.682	Down-regulation
AGC_PKG_PRKG2_ST	Q14847	LASP1	Q13237	PRKG2	S61	T63S	63	Missense	proximal	2	no	45.490	45.333	EPSD	COSMIC	42.682	Down-regulation
AGC_PKG_PRKG2_ST	Q14847	LASP1	Q13237	PRKG2	S61	M64T	64	Missense	distal	3	no	45.490	45.805	EPSD	COSMIC	42.682	Up-regulation
AGC_PKG_PRKG2_ST	Q14847	LASP1	Q13237	PRKG2	S146	E140Q	140	Missense	distal	-6	no	70.509	68.146	PhosphoSitePlus	COSMIC	42.682	Down-regulation
AGC_PKG_PRKG2_ST	Q14847	LASP1	Q13237	PRKG2	S146	R153W	153	Missense	distal	7	no	70.509	70.210	PhosphoSitePlus	COSMIC;GDSC	42.682	Down-regulation
AGC_PKG_PRKG2_ST	Q14847	LASP1	Q13237	PRKG2	S146	R144L	144	Missense	proximal	-2	no	70.509	58.431	PhosphoSitePlus	COSMIC	42.682	Down-regulation
AGC_PKG_PRKG2_ST	Q14847	LASP1	Q13237	PRKG2	S146	G149D	149	Missense	distal	3	no	70.509	70.984	PhosphoSitePlus	COSMIC	42.682	Up-regulation
AGC_PKG_PRKG2_ST	Q03393	PTS	Q13237	PRKG2	S19	V14A	14	Missense	distal	-5	no	67.947	67.946	PhosphoSitePlus	COSMIC	42.682	Down-regulation
AGC_PKG_PRKG2_ST	P32929	CTH	Q13237	PRKG2	S377	G379V	379	Missense	proximal	2	no	68.731	68.418	PhosphoSitePlus	COSMIC	42.682	Down-regulation
AGC_PKG_PRKG2_ST	P08581	MET	Q13237	PRKG2	S441	F445L	445	Missense	distal	4	no	48.721	48.236	EPSD	COSMIC	42.682	Down-regulation
AGC_PKG_PRKG2_ST	P08581	MET	Q13237	PRKG2	S441	F434I	434	Missense	distal	-7	no	48.721	51.250	EPSD	COSMIC	42.682	Up-regulation
AGC_PKG_PRKG2_ST	P08581	MET	Q13237	PRKG2	S441	F434L	434	Missense	distal	-7	no	48.721	50.876	EPSD	COSMIC	42.682	Up-regulation
AGC_PKG_PRKG2_ST	P08581	MET	Q13237	PRKG2	S441	F434C	434	Missense	distal	-7	no	48.721	50.076	EPSD	COSMIC	42.682	Up-regulation
AGC_PKG_PRKG2_ST	P08581	MET	Q13237	PRKG2	S758	I754V	754	Missense	distal	-4	no	44.324	42.099	EPSD	COSMIC	42.682	Loss
AGC_PKG_PRKG2_ST	P08581	MET	Q13237	PRKG2	S758	G764E	764	Missense	distal	6	no	44.324	44.101	EPSD	COSMIC	42.682	Down-regulation
AGC_PKG_PRKG2_ST	P08581	MET	Q13237	PRKG2	S985	T992I	992	Missense	distal	7	no	69.823	69.763	PhosphoSitePlus	COSMIC	42.682	Down-regulation
AGC_PKG_PRKG2_ST	P08581	MET	Q13237	PRKG2	S985	V984A	984	Missense	proximal	-1	no	69.823	69.746	PhosphoSitePlus	COSMIC	42.682	Down-regulation
AGC_PKG_PRKG2_ST	P08581	MET	Q13237	PRKG2	S985	A986D	986	Missense	proximal	1	no	69.823	69.485	PhosphoSitePlus	COSMIC	42.682	Down-regulation
AGC_PKG_PRKG2_ST	P08581	MET	Q13237	PRKG2	S985	R987Q	987	Missense	proximal	2	no	69.823	69.966	PhosphoSitePlus	COSMIC	42.682	Up-regulation
AGC_PKG_PRKG2_ST	P08581	MET	Q13237	PRKG2	S985	L980V	980	Missense	distal	-5	no	69.823	69.793	PhosphoSitePlus	COSMIC	42.682	Down-regulation
AGC_PKG_PRKG2_ST	P08581	MET	Q13237	PRKG2	S985	P991S	991	Missense	distal	6	no	69.823	69.107	PhosphoSitePlus	COSMIC	42.682	Down-regulation
AGC_PKG_PRKG2_ST	P08581	MET	Q13237	PRKG2	S985	P978S	978	Missense	distal	-7	no	69.823	69.511	PhosphoSitePlus	COSMIC	42.682	Down-regulation
AGC_PKG_PRKG2_ST	P08581	MET	Q13237	PRKG2	S988	T992I	992	Missense	distal	4	no	47.275	46.113	EPSD	COSMIC	42.682	Down-regulation
AGC_PKG_PRKG2_ST	P08581	MET	Q13237	PRKG2	S988	V984A	984	Missense	distal	-4	no	47.275	46.109	EPSD	COSMIC	42.682	Down-regulation
AGC_PKG_PRKG2_ST	P08581	MET	Q13237	PRKG2	S988	A986D	986	Missense	proximal	-2	no	47.275	44.558	EPSD	COSMIC	42.682	Down-regulation
AGC_PKG_PRKG2_ST	P08581	MET	Q13237	PRKG2	S988	M995T	995	Missense	distal	7	no	47.275	47.424	EPSD	COSMIC	42.682	Up-regulation
AGC_PKG_PRKG2_ST	P08581	MET	Q13237	PRKG2	S988	R987Q	987	Missense	proximal	-1	no	47.275	47.363	EPSD	COSMIC	42.682	Up-regulation
AGC_PKG_PRKG2_ST	P08581	MET	Q13237	PRKG2	S988	T993A	993	Missense	distal	5	no	47.275	47.377	EPSD	COSMIC	42.682	Up-regulation
AGC_PKG_PRKG2_ST	P08581	MET	Q13237	PRKG2	S988	P991S	991	Missense	distal	3	no	47.275	47.802	EPSD	COSMIC	42.682	Up-regulation
AGC_PKG_PRKG2_ST	P08581	MET	Q13237	PRKG2	S990	T992I	992	Missense	proximal	2	no	44.688	44.679	EPSD	COSMIC	42.682	Down-regulation
AGC_PKG_PRKG2_ST	P08581	MET	Q13237	PRKG2	S990	V984A	984	Missense	distal	-6	no	44.688	46.667	EPSD	COSMIC	42.682	Up-regulation
AGC_PKG_PRKG2_ST	P08581	MET	Q13237	PRKG2	S990	A986D	986	Missense	distal	-4	no	44.688	45.691	EPSD	COSMIC	42.682	Up-regulation
AGC_PKG_PRKG2_ST	P08581	MET	Q13237	PRKG2	S990	M995T	995	Missense	distal	5	no	44.688	45.193	EPSD	COSMIC	42.682	Up-regulation
AGC_PKG_PRKG2_ST	P08581	MET	Q13237	PRKG2	S990	R987Q	987	Missense	distal	-3	no	44.688	28.484	EPSD	COSMIC	42.682	Loss
AGC_PKG_PRKG2_ST	P08581	MET	Q13237	PRKG2	S990	T993A	993	Missense	distal	3	no	44.688	44.897	EPSD	COSMIC	42.682	Up-regulation
AGC_PKG_PRKG2_ST	P08581	MET	Q13237	PRKG2	S990	P991S	991	Missense	proximal	1	no	44.688	45.518	EPSD	COSMIC	42.682	Up-regulation
AGC_PKG_PRKG2_ST	P08581	MET	Q13237	PRKG2	T1006	Y1003S	1003	Missense	distal	-3	no	26.231	48.535	EPSD	COSMIC	42.682	Gain
AGC_PKG_PRKG2_ST	P08581	MET	Q13237	PRKG2	S1020	R1022L	1022	Missense	proximal	2	no	50.309	50.656	EPSD	COSMIC	42.682	Up-regulation
AGC_PKG_PRKG2_ST	P08581	MET	Q13237	PRKG2	S1020	S1020P	1020	Missense	central	0	yes	50.309	0.000	EPSD	COSMIC	42.682	Loss
AGC_PKG_PRKG2_ST	P08581	MET	Q13237	PRKG2	T1241	H1238R	1238	Missense	distal	-3	no	40.136	53.953	EPSD	COSMIC	42.682	Gain
AGC_PKG_PRKG2_ST	P08581	MET	Q13237	PRKG2	S1338	R1336Q	1336	Missense	proximal	-2	no	57.530	42.516	EPSD	COSMIC	42.682	Loss
AGC_PKG_PRKG2_ST	P08581	MET	Q13237	PRKG2	S1338	F1341L	1341	Missense	distal	3	no	57.530	57.310	EPSD	COSMIC	42.682	Down-regulation
AGC_PKG_PRKG2_ST	P08581	MET	Q13237	PRKG2	S1338	I1345T	1345	Missense	distal	7	no	57.530	57.590	EPSD	COSMIC	42.682	Up-regulation
TK_Fer_FER_Y	Q16555	DPYSL2	P16591	FER	Y479	R481H	481	Missense	proximal	2	no	0.174	0.158	EPSD;PhosphoSitePlus	COSMIC	0.101	Down-regulation
TK_Fer_FER_Y	Q16555	DPYSL2	P16591	FER	Y479	R481C	481	Missense	proximal	2	no	0.174	0.153	EPSD;PhosphoSitePlus	COSMIC	0.101	Down-regulation
TK_Fer_FER_Y	Q16555	DPYSL2	P16591	FER	Y499	R496Q	496	Missense	distal	-3	no	0.191	0.190	PhosphoSitePlus;EPSD	COSMIC	0.101	Down-regulation
TK_Fer_FER_Y	Q16555	DPYSL2	P16591	FER	Y499	V506A	506	Missense	distal	7	no	0.191	0.195	PhosphoSitePlus;EPSD	COSMIC	0.101	Up-regulation
TK_Fer_FER_Y	Q16555	DPYSL2	P16591	FER	Y499	R492K	492	Missense	distal	-7	no	0.191	0.188	PhosphoSitePlus;EPSD	COSMIC	0.101	Down-regulation
TK_Fer_FER_Y	P15311	EZR	P16591	FER	Y354	R350Q	350	Missense	distal	-4	no	0.173	0.167	EPSD;PhosphoSitePlus	COSMIC	0.101	Down-regulation
TK_Fer_FER_Y	P15311	EZR	P16591	FER	Y354	R350W	350	Missense	distal	-4	no	0.173	0.164	EPSD;PhosphoSitePlus	COSMIC	0.101	Down-regulation
TK_Fer_FER_Y	P15311	EZR	P16591	FER	Y478	P480L	480	Missense	proximal	2	no	0.203	0.204	PhosphoSitePlus;EPSD	COSMIC	0.101	Up-regulation
TK_Fer_FER_Y	P15311	EZR	P16591	FER	Y483	P480L	480	Missense	distal	-3	no	0.131	0.132	EPSD	COSMIC	0.101	Up-regulation
TK_Fer_FER_Y	P08581	MET	P16591	FER	Y1235	G1242D	1242	Missense	distal	7	no	0.102	0.113	EPSD	COSMIC	0.101	Up-regulation
TK_Fer_FER_Y	P08581	MET	P16591	FER	Y1235	G1242A	1242	Missense	distal	7	no	0.102	0.109	EPSD	COSMIC	0.101	Up-regulation
TK_Fer_FER_Y	P08581	MET	P16591	FER	Y1235	Y1235D	1235	Missense	central	0	yes	0.102	0.000	EPSD	COSMIC	0.101	Loss
TK_Fer_FER_Y	P08581	MET	P16591	FER	Y1235	Y1230S	1230	Missense	distal	-5	no	0.102	0.095	EPSD	COSMIC	0.101	Loss
TK_Fer_FER_Y	P08581	MET	P16591	FER	Y1235	D1228N	1228	Missense	distal	-7	no	0.102	0.093	EPSD	COSMIC	0.101	Loss
TK_Fer_FER_Y	P08581	MET	P16591	FER	Y1235	M1229L	1229	Missense	distal	-6	no	0.102	0.101	EPSD	COSMIC	0.101	Down-regulation
TK_Fer_FER_Y	P08581	MET	P16591	FER	Y1235	D1231N	1231	Missense	distal	-4	no	0.102	0.081	EPSD	COSMIC	0.101	Loss
TK_Fer_FER_Y	P08581	MET	P16591	FER	Y1235	G1242C	1242	Missense	distal	7	no	0.102	0.098	EPSD	COSMIC	0.101	Loss
TK_Fer_FER_Y	P08581	MET	P16591	FER	Y1235	D1228V	1228	Missense	distal	-7	no	0.102	0.087	EPSD	COSMIC	0.101	Loss
TK_Fer_FER_Y	P08581	MET	P16591	FER	Y1235	H1238R	1238	Missense	distal	3	no	0.102	0.101	EPSD	COSMIC	0.101	Down-regulation
TK_Fer_FER_Y	P08581	MET	P16591	FER	Y1235	M1229V	1229	Missense	distal	-6	no	0.102	0.101	EPSD	COSMIC	0.101	Down-regulation
TK_Fer_FER_Y	P08581	MET	P16591	FER	Y1349	H1348N	1348	Missense	proximal	-1	no	0.204	0.213	PhosphoSitePlus	COSMIC	0.101	Up-regulation
TK_Fer_FER_Y	P08581	MET	P16591	FER	Y1349	A1354P	1354	Missense	distal	5	no	0.204	0.209	PhosphoSitePlus	COSMIC	0.101	Up-regulation
TK_Fer_FER_Y	P08581	MET	P16591	FER	Y1349	G1346W	1346	Missense	distal	-3	no	0.204	0.203	PhosphoSitePlus	COSMIC	0.101	Down-regulation
TK_Fer_FER_Y	P08581	MET	P16591	FER	Y1349	I1345T	1345	Missense	distal	-4	no	0.204	0.220	PhosphoSitePlus	COSMIC	0.101	Up-regulation
TK_Fer_FER_Y	P10275	AR	P16591	FER	Y225	D223N	223	Missense	proximal	-2	no	0.181	0.178	PhosphoSitePlus	COSMIC	0.101	Down-regulation
TK_Fer_FER_Y	P10275	AR	P16591	FER	Y225	S220F	220	Missense	distal	-5	no	0.181	0.223	PhosphoSitePlus	COSMIC	0.101	Up-regulation
TK_Fer_FER_Y	P10275	AR	P16591	FER	Y225	N224S	224	Missense	proximal	-1	no	0.181	0.172	PhosphoSitePlus	COSMIC	0.101	Down-regulation
TK_Fer_FER_Y	P10275	AR	P16591	FER	Y225	T229I	229	Missense	distal	4	no	0.181	0.171	PhosphoSitePlus	COSMIC	0.101	Down-regulation
TK_Fer_FER_Y	P10275	AR	P16591	FER	Y225	L226V	226	Missense	proximal	1	no	0.181	0.156	PhosphoSitePlus	COSMIC	0.101	Down-regulation
TK_Fer_FER_Y	P10275	AR	P16591	FER	Y225	D223H	223	Missense	proximal	-2	no	0.181	0.178	PhosphoSitePlus	COSMIC	0.101	Down-regulation
TK_Fer_FER_Y	P10275	AR	P16591	FER	Y225	Y225D	225	Missense	central	0	yes	0.181	0.000	PhosphoSitePlus	COSMIC	0.101	Loss
TK_Fer_FER_Y	P10275	AR	P16591	FER	Y225	T229C	229	Missense	distal	4	no	0.181	0.156	PhosphoSitePlus	COSMIC	0.101	Down-regulation
TK_Fer_FER_Y	P10275	AR	P16591	FER	Y309	E304K	304	Missense	distal	-5	no	0.095	0.105	EPSD	COSMIC	0.101	Gain
TK_Fer_FER_Y	P10275	AR	P16591	FER	Y535	G536E	536	Missense	proximal	1	no	0.058	0.101	EPSD	COSMIC	0.101	Gain
TK_Fer_FER_Y	P40763	STAT3	P16591	FER	Y539	G541R	541	Missense	proximal	2	no	0.095	0.114	EPSD	COSMIC	0.101	Gain
TK_Fer_FER_Y	P40763	STAT3	P16591	FER	Y674	Y672C	672	Missense	proximal	-2	no	0.132	0.131	EPSD	COSMIC;GDSC;CCLE	0.101	Down-regulation
TK_Fer_FER_Y	P40763	STAT3	P16591	FER	Y674	P669T	669	Missense	distal	-5	no	0.132	0.092	EPSD	COSMIC	0.101	Loss
TK_Fer_FER_Y	P40763	STAT3	P16591	FER	Y674	P675T	675	Missense	proximal	1	no	0.132	0.166	EPSD	COSMIC	0.101	Up-regulation
TK_Fer_FER_Y	P40763	STAT3	P16591	FER	Y674	V671F	671	Missense	distal	-3	no	0.132	0.128	EPSD	COSMIC	0.101	Down-regulation
TK_Fer_FER_Y	P40763	STAT3	P16591	FER	Y705	D698N	698	Missense	distal	-7	no	0.182	0.173	PhosphoSitePlus	COSMIC	0.101	Down-regulation
TK_Fer_FER_Y	P40763	STAT3	P16591	FER	Y705	G700R	700	Missense	distal	-5	no	0.182	0.153	PhosphoSitePlus	COSMIC	0.101	Down-regulation
TK_Fer_FER_Y	P40763	STAT3	P16591	FER	Y705	I711L	711	Missense	distal	6	no	0.182	0.180	PhosphoSitePlus	COSMIC	0.101	Down-regulation
TK_Fer_FER_Y	P16591	FER	P16591	FER	Y229	D227N	227	Missense	proximal	-2	no	0.133	0.131	EPSD	COSMIC	0.101	Down-regulation
TK_Fer_FER_Y	P16591	FER	P16591	FER	Y229	E228K	228	Missense	proximal	-1	no	0.133	0.137	EPSD	COSMIC	0.101	Up-regulation
TK_Fer_FER_Y	P16591	FER	P16591	FER	Y229	I225V	225	Missense	distal	-4	no	0.133	0.105	EPSD	COSMIC	0.101	Down-regulation
TK_Fer_FER_Y	P16591	FER	P16591	FER	Y634	Q631H	631	Missense	distal	-3	no	0.116	0.108	EPSD	COSMIC	0.101	Down-regulation
TK_Fer_FER_Y	P16591	FER	P16591	FER	Y634	P632L	632	Missense	proximal	-2	no	0.116	0.117	EPSD	COSMIC	0.101	Up-regulation
TK_Fer_FER_Y	P14923	JUP	P16591	FER	Y133	N132K	132	Missense	proximal	-1	no	0.147	0.149	EPSD	COSMIC	0.101	Up-regulation
TK_Fer_FER_Y	P14923	JUP	P16591	FER	Y550	G545D	545	Missense	distal	-5	no	0.211	0.170	PhosphoSitePlus	COSMIC	0.101	Down-regulation
TK_Fer_FER_Y	Q13480	GAB1	P16591	FER	Y627	D631F	631	Missense	distal	4	no	0.170	0.128	PhosphoSitePlus	COSMIC	0.101	Down-regulation
TK_Fer_FER_Y	Q13480	GAB1	P16591	FER	Y627	D631Y	631	Missense	distal	4	no	0.170	0.141	PhosphoSitePlus	COSMIC	0.101	Down-regulation
TK_Fer_FER_Y	Q13480	GAB1	P16591	FER	Y627	D631V	631	Missense	distal	4	no	0.170	0.137	PhosphoSitePlus	COSMIC	0.101	Down-regulation
TK_Fer_FER_Y	Q13480	GAB1	P16591	FER	Y627	Q624L	624	Missense	distal	-3	no	0.170	0.164	PhosphoSitePlus	COSMIC	0.101	Down-regulation
TK_Fer_FER_Y	Q13480	GAB1	P16591	FER	Y627	L632I	632	Missense	distal	5	no	0.170	0.159	PhosphoSitePlus	COSMIC	0.101	Down-regulation
TK_Fer_FER_Y	Q13480	GAB1	P16591	FER	Y627	D631N	631	Missense	distal	4	no	0.170	0.153	PhosphoSitePlus	COSMIC	0.101	Down-regulation
CMGC_CDK_CDK9_CDK9_ST	O00267	SUPT5H	P50750	CDK9	S108	S108F	108	Missense	central	0	yes	2.024	0.000	EPSD	COSMIC	1.932	Loss
CMGC_CDK_CDK9_CDK9_ST	O00267	SUPT5H	P50750	CDK9	T208	V215I	215	Missense	distal	7	no	5.170	5.174	EPSD	COSMIC	1.932	Up-regulation
CMGC_CDK_CDK9_CDK9_ST	O00267	SUPT5H	P50750	CDK9	T655	V659M	659	Missense	distal	4	no	2.325	2.356	EPSD	COSMIC	1.932	Up-regulation
CMGC_CDK_CDK9_CDK9_ST	O00267	SUPT5H	P50750	CDK9	S666	V659M	659	Missense	distal	-7	no	6.182	6.178	EPSD;PhosphoSitePlus	COSMIC	1.932	Down-regulation
CMGC_CDK_CDK9_CDK9_ST	O00267	SUPT5H	P50750	CDK9	S666	M665T	665	Missense	proximal	-1	no	6.182	6.192	EPSD;PhosphoSitePlus	COSMIC	1.932	Up-regulation
CMGC_CDK_CDK9_CDK9_ST	O00267	SUPT5H	P50750	CDK9	S666	P672L	672	Missense	distal	6	no	6.182	5.577	EPSD;PhosphoSitePlus	COSMIC	1.932	Down-regulation
CMGC_CDK_CDK9_CDK9_ST	O00267	SUPT5H	P50750	CDK9	S671	M665T	665	Missense	distal	-6	no	5.138	5.246	EPSD	COSMIC	1.932	Up-regulation
CMGC_CDK_CDK9_CDK9_ST	O00267	SUPT5H	P50750	CDK9	S671	P672L	672	Missense	proximal	1	no	5.138	-0.461	EPSD	COSMIC	1.932	Loss
CMGC_CDK_CDK9_CDK9_ST	O00267	SUPT5H	P50750	CDK9	S686	R681H	681	Missense	distal	-5	no	4.609	4.579	EPSD	COSMIC	1.932	Down-regulation
CMGC_CDK_CDK9_CDK9_ST	O00267	SUPT5H	P50750	CDK9	S738	T739P	739	Missense	proximal	1	no	0.971	4.990	EPSD	COSMIC	1.932	Gain
CMGC_CDK_CDK9_CDK9_ST	O00267	SUPT5H	P50750	CDK9	T784	P785S	785	Missense	proximal	1	no	5.620	1.886	EPSD;PhosphoSitePlus	COSMIC	1.932	Loss
CMGC_CDK_CDK9_CDK9_ST	O00267	SUPT5H	P50750	CDK9	T784	G788D	788	Missense	distal	4	no	5.620	5.573	EPSD;PhosphoSitePlus	COSMIC	1.932	Down-regulation
CMGC_CDK_CDK9_CDK9_ST	O00267	SUPT5H	P50750	CDK9	T784	G788S	788	Missense	distal	4	no	5.620	5.718	EPSD;PhosphoSitePlus	COSMIC	1.932	Up-regulation
CMGC_CDK_CDK9_CDK9_ST	O00267	SUPT5H	P50750	CDK9	T784	S789L	789	Missense	distal	5	no	5.620	5.175	EPSD;PhosphoSitePlus	COSMIC;GDSC;CCLE	1.932	Down-regulation
CMGC_CDK_CDK9_CDK9_ST	O00267	SUPT5H	P50750	CDK9	T791	P785S	785	Missense	distal	-6	no	6.618	6.486	EPSD;PhosphoSitePlus	COSMIC	1.932	Down-regulation
CMGC_CDK_CDK9_CDK9_ST	O00267	SUPT5H	P50750	CDK9	T791	G788D	788	Missense	distal	-3	no	6.618	6.619	EPSD;PhosphoSitePlus	COSMIC	1.932	Up-regulation
CMGC_CDK_CDK9_CDK9_ST	O00267	SUPT5H	P50750	CDK9	T791	G788S	788	Missense	distal	-3	no	6.618	6.536	EPSD;PhosphoSitePlus	COSMIC	1.932	Down-regulation
CMGC_CDK_CDK9_CDK9_ST	O00267	SUPT5H	P50750	CDK9	T791	S789L	789	Missense	proximal	-2	no	6.618	6.067	EPSD;PhosphoSitePlus	COSMIC;GDSC;CCLE	1.932	Down-regulation
CMGC_CDK_CDK9_CDK9_ST	O00267	SUPT5H	P50750	CDK9	S812	G819W	819	Missense	distal	7	no	2.029	2.084	EPSD	COSMIC	1.932	Up-regulation
CMGC_CDK_CDK9_CDK9_ST	O00267	SUPT5H	P50750	CDK9	S812	A816V	816	Missense	distal	4	no	2.029	2.015	EPSD	COSMIC	1.932	Down-regulation
CMGC_CDK_CDK9_CDK9_ST	O00267	SUPT5H	P50750	CDK9	S812	S818G	818	Missense	distal	6	no	2.029	1.519	EPSD	COSMIC	1.932	Loss
CMGC_CDK_CDK9_CDK9_ST	O00267	SUPT5H	P50750	CDK9	T814	G819W	819	Missense	distal	5	no	6.210	6.074	PhosphoSitePlus;EPSD	COSMIC	1.932	Down-regulation
CMGC_CDK_CDK9_CDK9_ST	O00267	SUPT5H	P50750	CDK9	T814	A816V	816	Missense	proximal	2	no	6.210	6.185	PhosphoSitePlus;EPSD	COSMIC	1.932	Down-regulation
CMGC_CDK_CDK9_CDK9_ST	O00267	SUPT5H	P50750	CDK9	T814	S818G	818	Missense	distal	4	no	6.210	6.111	PhosphoSitePlus;EPSD	COSMIC	1.932	Down-regulation
CMGC_CDK_CDK9_CDK9_ST	O00267	SUPT5H	P50750	CDK9	T828	E834K	834	Missense	distal	6	no	4.793	4.849	EPSD	COSMIC	1.932	Up-regulation
CMGC_CDK_CDK9_CDK9_ST	O00267	SUPT5H	P50750	CDK9	T845	D841N	841	Missense	distal	-4	no	3.710	3.786	EPSD	COSMIC	1.932	Up-regulation
CMGC_CDK_CDK9_CDK9_ST	O00267	SUPT5H	P50750	CDK9	T845	P848L	848	Missense	distal	3	no	3.710	3.365	EPSD	COSMIC	1.932	Down-regulation
CMGC_CDK_CDK9_CDK9_ST	O00267	SUPT5H	P50750	CDK9	T845	P844L	844	Missense	proximal	-1	no	3.710	3.672	EPSD	COSMIC	1.932	Down-regulation
CMGC_CDK_CDK9_CDK9_ST	O00267	SUPT5H	P50750	CDK9	S847	D841N	841	Missense	distal	-6	no	3.374	3.624	EPSD	COSMIC	1.932	Up-regulation
CMGC_CDK_CDK9_CDK9_ST	O00267	SUPT5H	P50750	CDK9	S847	P848L	848	Missense	proximal	1	no	3.374	-2.224	EPSD	COSMIC	1.932	Loss
CMGC_CDK_CDK9_CDK9_ST	O00267	SUPT5H	P50750	CDK9	S847	P844L	844	Missense	distal	-3	no	3.374	3.459	EPSD	COSMIC	1.932	Up-regulation
CMGC_CDK_CDK9_CDK9_ST	O00267	SUPT5H	P50750	CDK9	T854	P857S	857	Missense	distal	3	no	6.761	6.726	EPSD	COSMIC	1.932	Down-regulation
CMGC_CDK_CDK9_CDK9_ST	O00267	SUPT5H	P50750	CDK9	T854	P857L	857	Missense	distal	3	no	6.761	6.415	EPSD	COSMIC	1.932	Down-regulation
CMGC_CDK_CDK9_CDK9_ST	O00267	SUPT5H	P50750	CDK9	T854	P848L	848	Missense	distal	-6	no	6.761	6.172	EPSD	COSMIC	1.932	Down-regulation
CMGC_CDK_CDK9_CDK9_ST	O00267	SUPT5H	P50750	CDK9	T859	D864H	864	Missense	distal	5	no	5.525	5.596	EPSD	COSMIC	1.932	Up-regulation
CMGC_CDK_CDK9_CDK9_ST	O00267	SUPT5H	P50750	CDK9	T859	P857S	857	Missense	proximal	-2	no	5.525	5.286	EPSD	COSMIC	1.932	Down-regulation
CMGC_CDK_CDK9_CDK9_ST	O00267	SUPT5H	P50750	CDK9	T859	S866L	866	Missense	distal	7	no	5.525	5.826	EPSD	COSMIC	1.932	Up-regulation
CMGC_CDK_CDK9_CDK9_ST	O00267	SUPT5H	P50750	CDK9	T859	P857L	857	Missense	proximal	-2	no	5.525	4.736	EPSD	COSMIC	1.932	Down-regulation
CMGC_CDK_CDK9_CDK9_ST	O00267	SUPT5H	P50750	CDK9	S867	D864H	864	Missense	distal	-3	no	5.181	5.169	EPSD	COSMIC	1.932	Down-regulation
CMGC_CDK_CDK9_CDK9_ST	O00267	SUPT5H	P50750	CDK9	S867	P872A	872	Missense	distal	5	no	5.181	4.903	EPSD	COSMIC	1.932	Down-regulation
CMGC_CDK_CDK9_CDK9_ST	O00267	SUPT5H	P50750	CDK9	S867	S866L	866	Missense	proximal	-1	no	5.181	5.107	EPSD	COSMIC	1.932	Down-regulation
CMGC_CDK_CDK9_CDK9_ST	O00267	SUPT5H	P50750	CDK9	S867	P868A	868	Missense	proximal	1	no	5.181	0.017	EPSD	COSMIC	1.932	Loss
CMGC_CDK_CDK9_CDK9_ST	O00267	SUPT5H	P50750	CDK9	T878	P872A	872	Missense	distal	-6	no	4.472	3.944	EPSD	COSMIC	1.932	Down-regulation
CMGC_CDK_CDK9_CDK9_ST	O00267	SUPT5H	P50750	CDK9	T881	N886S	886	Missense	distal	5	no	4.187	4.408	EPSD	COSMIC	1.932	Up-regulation
CMGC_CDK_CDK9_CDK9_ST	O00267	SUPT5H	P50750	CDK9	S897	P892S	892	Missense	distal	-5	no	4.658	4.743	EPSD	COSMIC	1.932	Up-regulation
CMGC_CDK_CDK9_CDK9_ST	O00267	SUPT5H	P50750	CDK9	S951	P958L	958	Missense	distal	7	no	5.788	6.051	EPSD	COSMIC	1.932	Up-regulation
CMGC_CDK_CDK9_CDK9_ST	O00267	SUPT5H	P50750	CDK9	S951	P958S	958	Missense	distal	7	no	5.788	5.750	EPSD	COSMIC	1.932	Down-regulation
CMGC_CDK_CDK9_CDK9_ST	O00267	SUPT5H	P50750	CDK9	S951	P945L	945	Missense	distal	-6	no	5.788	5.198	EPSD	COSMIC	1.932	Down-regulation
CMGC_CDK_CDK9_CDK9_ST	O00267	SUPT5H	P50750	CDK9	T954	P958L	958	Missense	distal	4	no	5.814	5.773	EPSD	COSMIC	1.932	Down-regulation
CMGC_CDK_CDK9_CDK9_ST	O00267	SUPT5H	P50750	CDK9	T954	P958S	958	Missense	distal	4	no	5.814	5.908	EPSD	COSMIC	1.932	Up-regulation
CMGC_CDK_CDK9_CDK9_ST	O00267	SUPT5H	P50750	CDK9	S959	P958L	958	Missense	proximal	-1	no	5.389	5.351	EPSD	COSMIC	1.932	Down-regulation
CMGC_CDK_CDK9_CDK9_ST	O00267	SUPT5H	P50750	CDK9	S959	P958S	958	Missense	proximal	-1	no	5.389	5.425	EPSD	COSMIC	1.932	Up-regulation
CMGC_CDK_CDK9_CDK9_ST	O00267	SUPT5H	P50750	CDK9	S959	G962V	962	Missense	distal	3	no	5.389	5.388	EPSD	COSMIC	1.932	Down-regulation
CMGC_CDK_CDK9_CDK9_ST	O00267	SUPT5H	P50750	CDK9	T967	T967P	967	Missense	central	0	yes	5.577	0.000	EPSD	COSMIC	1.932	Loss
CMGC_CDK_CDK9_CDK9_ST	O00267	SUPT5H	P50750	CDK9	T967	G962V	962	Missense	distal	-5	no	5.577	5.516	EPSD	COSMIC	1.932	Down-regulation
CMGC_CDK_CDK9_CDK9_ST	O00267	SUPT5H	P50750	CDK9	S976	D983G	983	Missense	distal	7	no	2.177	2.147	EPSD	COSMIC	1.932	Down-regulation
CMGC_CDK_CDK9_CDK9_ST	O00267	SUPT5H	P50750	CDK9	S976	V980I	980	Missense	distal	4	no	2.177	2.186	EPSD	COSMIC	1.932	Up-regulation
CMGC_CDK_CDK9_CDK9_ST	O00267	SUPT5H	P50750	CDK9	S1026	V1023I	1023	Missense	distal	-3	no	2.387	2.389	EPSD	COSMIC	1.932	Up-regulation
CMGC_CDK_CDK9_CDK9_ST	O00267	SUPT5H	P50750	CDK9	T1034	N1039S	1039	Missense	distal	5	no	5.754	5.974	EPSD	COSMIC	1.932	Up-regulation
CMGC_CDK_CDK9_CDK9_ST	O00267	SUPT5H	P50750	CDK9	T1034	K1040R	1040	Missense	distal	6	no	5.754	5.697	EPSD	COSMIC	1.932	Down-regulation
CMGC_CDK_CDK9_CDK9_ST	O00267	SUPT5H	P50750	CDK9	T1034	N1039K	1039	Missense	distal	5	no	5.754	5.673	EPSD	COSMIC	1.932	Down-regulation
CMGC_CDK_CDK9_CDK9_ST	Q15797	SMAD1	P50750	CDK9	T10	K15R	15	Missense	distal	5	no	2.283	2.250	EPSD	COSMIC	1.932	Down-regulation
CMGC_CDK_CDK9_CDK9_ST	Q15797	SMAD1	P50750	CDK9	T10	K15N	15	Missense	distal	5	no	2.283	2.365	EPSD	COSMIC	1.932	Up-regulation
CMGC_CDK_CDK9_CDK9_ST	Q15797	SMAD1	P50750	CDK9	S11	K15R	15	Missense	distal	4	no	4.480	4.471	EPSD	COSMIC	1.932	Down-regulation
CMGC_CDK_CDK9_CDK9_ST	Q15797	SMAD1	P50750	CDK9	S11	K15N	15	Missense	distal	4	no	4.480	4.502	EPSD	COSMIC	1.932	Up-regulation
CMGC_CDK_CDK9_CDK9_ST	Q15797	SMAD1	P50750	CDK9	S62	S56N	56	Missense	distal	-6	no	2.622	2.478	EPSD	COSMIC;GDSC;CCLE	1.932	Down-regulation
CMGC_CDK_CDK9_CDK9_ST	Q15797	SMAD1	P50750	CDK9	S62	C57F	57	Missense	distal	-5	no	2.622	2.626	EPSD	COSMIC;GDSC;CCLE	1.932	Up-regulation
CMGC_CDK_CDK9_CDK9_ST	Q15797	SMAD1	P50750	CDK9	S62	L55F	55	Missense	distal	-7	no	2.622	2.623	EPSD	COSMIC	1.932	Up-regulation
CMGC_CDK_CDK9_CDK9_ST	Q15797	SMAD1	P50750	CDK9	S132	V130L	130	Missense	proximal	-2	no	5.932	5.794	EPSD	COSMIC	1.932	Down-regulation
CMGC_CDK_CDK9_CDK9_ST	Q15797	SMAD1	P50750	CDK9	S132	Y127C	127	Missense	distal	-5	no	5.932	5.852	EPSD	COSMIC	1.932	Down-regulation
CMGC_CDK_CDK9_CDK9_ST	Q15797	SMAD1	P50750	CDK9	S187	P188S	188	Missense	proximal	1	no	5.904	2.170	EPSD;PhosphoSitePlus	COSMIC	1.932	Down-regulation
CMGC_CDK_CDK9_CDK9_ST	Q15797	SMAD1	P50750	CDK9	S187	P183L	183	Missense	distal	-4	no	5.904	5.770	EPSD;PhosphoSitePlus	COSMIC;CCLE	1.932	Down-regulation
CMGC_CDK_CDK9_CDK9_ST	Q15797	SMAD1	P50750	CDK9	S195	P188S	188	Missense	distal	-7	no	7.020	7.025	PhosphoSitePlus;EPSD	COSMIC	1.932	Up-regulation
CMGC_CDK_CDK9_CDK9_ST	Q15797	SMAD1	P50750	CDK9	S206	H205Y	205	Missense	proximal	-1	no	6.575	6.561	EPSD;PhosphoSitePlus	COSMIC	1.932	Down-regulation
CMGC_CDK_CDK9_CDK9_ST	Q15797	SMAD1	P50750	CDK9	S206	H205N	205	Missense	proximal	-1	no	6.575	6.589	EPSD;PhosphoSitePlus	COSMIC	1.932	Up-regulation
CMGC_CDK_CDK9_CDK9_ST	Q15797	SMAD1	P50750	CDK9	S315	S315F	315	Missense	central	0	yes	2.576	0.000	EPSD	COSMIC	1.932	Loss
CMGC_CDK_CDK9_CDK9_ST	P50750	CDK9	P50750	CDK9	T186	R184C	184	Missense	proximal	-2	no	2.467	2.259	PhosphoSitePlus;EPSD	COSMIC;GDSC;CCLE	1.932	Down-regulation
CMGC_CDK_CDK9_CDK9_ST	P50750	CDK9	P50750	CDK9	S347	A340T	340	Missense	distal	-7	no	3.411	3.389	EPSD;PhosphoSitePlus	COSMIC;GDSC;CCLE	1.932	Down-regulation
CMGC_CDK_CDK9_CDK9_ST	P50750	CDK9	P50750	CDK9	S347	R343C	343	Missense	distal	-4	no	3.411	3.360	EPSD;PhosphoSitePlus	COSMIC	1.932	Down-regulation
CMGC_CDK_CDK9_CDK9_ST	P50750	CDK9	P50750	CDK9	S347	S347C	347	Missense	central	0	yes	3.411	0.000	EPSD;PhosphoSitePlus	COSMIC;GDSC;CCLE	1.932	Loss
CMGC_CDK_CDK9_CDK9_ST	P50750	CDK9	P50750	CDK9	T350	R343C	343	Missense	distal	-7	no	3.328	3.350	EPSD	COSMIC	1.932	Up-regulation
CMGC_CDK_CDK9_CDK9_ST	P50750	CDK9	P50750	CDK9	T350	S347C	347	Missense	distal	-3	no	3.328	3.420	EPSD	COSMIC;GDSC;CCLE	1.932	Up-regulation
CMGC_CDK_CDK9_CDK9_ST	P50750	CDK9	P50750	CDK9	S353	S347C	347	Missense	distal	-6	no	2.921	2.478	EPSD;PhosphoSitePlus	COSMIC;GDSC;CCLE	1.932	Down-regulation
CMGC_CDK_CDK9_CDK9_ST	P50750	CDK9	P50750	CDK9	T354	A361T	361	Missense	distal	7	no	3.986	3.881	EPSD;PhosphoSitePlus	COSMIC;GDSC;CCLE	1.932	Down-regulation
CMGC_CDK_CDK9_CDK9_ST	P50750	CDK9	P50750	CDK9	T354	S347C	347	Missense	distal	-7	no	3.986	4.049	EPSD;PhosphoSitePlus	COSMIC;GDSC;CCLE	1.932	Up-regulation
CMGC_CDK_CDK9_CDK9_ST	P50750	CDK9	P50750	CDK9	S357	A361T	361	Missense	distal	4	no	2.355	2.389	EPSD	COSMIC;GDSC;CCLE	1.932	Up-regulation
CMGC_CDK_CDK9_CDK9_ST	P50750	CDK9	P50750	CDK9	T362	A361T	361	Missense	proximal	-1	no	2.325	2.349	EPSD;PhosphoSitePlus	COSMIC;GDSC;CCLE	1.932	Up-regulation
CMGC_CDK_CDK9_CDK9_ST	P50750	CDK9	P50750	CDK9	T363	A361T	361	Missense	proximal	-2	no	2.770	2.979	EPSD;PhosphoSitePlus	COSMIC;GDSC;CCLE	1.932	Up-regulation
CMGC_CDK_CDK9_CDK9_ST	P50750	CDK9	P50750	CDK9	T363	R370C	370	Missense	distal	7	no	2.770	2.875	EPSD;PhosphoSitePlus	COSMIC	1.932	Up-regulation
CMGC_CDK_CDK9_CDK9_ST	P84022	SMAD3	P50750	CDK9	T8	P9L	9	Missense	proximal	1	no	5.649	0.051	EPSD	COSMIC	1.932	Loss
CMGC_CDK_CDK9_CDK9_ST	P84022	SMAD3	P50750	CDK9	T8	I4V	4	Missense	distal	-4	no	5.649	5.646	EPSD	COSMIC	1.932	Down-regulation
CMGC_CDK_CDK9_CDK9_ST	P84022	SMAD3	P50750	CDK9	T132	H126R	126	Missense	distal	-6	no	5.100	5.143	EPSD	COSMIC	1.932	Up-regulation
CMGC_CDK_CDK9_CDK9_ST	P84022	SMAD3	P50750	CDK9	T132	P137L	137	Missense	distal	5	no	5.100	4.775	EPSD	COSMIC	1.932	Down-regulation
CMGC_CDK_CDK9_CDK9_ST	P84022	SMAD3	P50750	CDK9	T132	V134A	134	Missense	proximal	2	no	5.100	5.124	EPSD	COSMIC	1.932	Up-regulation
CMGC_CDK_CDK9_CDK9_ST	P84022	SMAD3	P50750	CDK9	T132	V138L	138	Missense	distal	6	no	5.100	5.018	EPSD	COSMIC	1.932	Down-regulation
CMGC_CDK_CDK9_CDK9_ST	P84022	SMAD3	P50750	CDK9	T132	P136R	136	Missense	distal	4	no	5.100	5.079	EPSD	COSMIC	1.932	Down-regulation
CMGC_CDK_CDK9_CDK9_ST	P84022	SMAD3	P50750	CDK9	T132	P133L	133	Missense	proximal	1	no	5.100	-0.498	EPSD	COSMIC	1.932	Loss
CMGC_CDK_CDK9_CDK9_ST	P84022	SMAD3	P50750	CDK9	T179	N175D	175	Missense	distal	-4	no	5.191	5.115	EPSD;PhosphoSitePlus	COSMIC	1.932	Down-regulation
CMGC_CDK_CDK9_CDK9_ST	P84022	SMAD3	P50750	CDK9	T179	P182S	182	Missense	distal	3	no	5.191	5.156	EPSD;PhosphoSitePlus	COSMIC	1.932	Down-regulation
CMGC_CDK_CDK9_CDK9_ST	P84022	SMAD3	P50750	CDK9	T179	P177L	177	Missense	proximal	-2	no	5.191	4.402	EPSD;PhosphoSitePlus	COSMIC	1.932	Down-regulation
CMGC_CDK_CDK9_CDK9_ST	P84022	SMAD3	P50750	CDK9	T179	P172H	172	Missense	distal	-7	no	5.191	5.244	EPSD;PhosphoSitePlus	COSMIC	1.932	Up-regulation
CMGC_CDK_CDK9_CDK9_ST	P84022	SMAD3	P50750	CDK9	S204	S204N	204	Missense	central	0	yes	5.359	0.000	EPSD	COSMIC	1.932	Loss
CMGC_CDK_CDK9_CDK9_ST	P84022	SMAD3	P50750	CDK9	S204	P211S	211	Missense	distal	7	no	5.359	5.321	EPSD	COSMIC	1.932	Down-regulation
CMGC_CDK_CDK9_CDK9_ST	P84022	SMAD3	P50750	CDK9	S204	A202T	202	Missense	proximal	-2	no	5.359	5.567	EPSD	COSMIC	1.932	Up-regulation
CMGC_CDK_CDK9_CDK9_ST	P84022	SMAD3	P50750	CDK9	S204	S204F	204	Missense	central	0	yes	5.359	0.000	EPSD	COSMIC	1.932	Loss
CMGC_CDK_CDK9_CDK9_ST	P84022	SMAD3	P50750	CDK9	S204	P211L	211	Missense	distal	7	no	5.359	5.622	EPSD	COSMIC	1.932	Up-regulation
CMGC_CDK_CDK9_CDK9_ST	P84022	SMAD3	P50750	CDK9	S204	P209S	209	Missense	distal	5	no	5.359	5.478	EPSD	COSMIC	1.932	Up-regulation
CMGC_CDK_CDK9_CDK9_ST	P84022	SMAD3	P50750	CDK9	S204	N197K	197	Missense	distal	-7	no	5.359	5.370	EPSD	COSMIC	1.932	Up-regulation
CMGC_CDK_CDK9_CDK9_ST	P84022	SMAD3	P50750	CDK9	S208	S204N	204	Missense	distal	-4	no	6.205	6.131	PhosphoSitePlus;EPSD	COSMIC	1.932	Down-regulation
CMGC_CDK_CDK9_CDK9_ST	P84022	SMAD3	P50750	CDK9	S208	P211S	211	Missense	distal	3	no	6.205	6.170	PhosphoSitePlus;EPSD	COSMIC	1.932	Down-regulation
CMGC_CDK_CDK9_CDK9_ST	P84022	SMAD3	P50750	CDK9	S208	A202T	202	Missense	distal	-6	no	6.205	6.366	PhosphoSitePlus;EPSD	COSMIC	1.932	Up-regulation
CMGC_CDK_CDK9_CDK9_ST	P84022	SMAD3	P50750	CDK9	S208	S204F	204	Missense	distal	-4	no	6.205	6.040	PhosphoSitePlus;EPSD	COSMIC	1.932	Down-regulation
CMGC_CDK_CDK9_CDK9_ST	P84022	SMAD3	P50750	CDK9	S208	P211L	211	Missense	distal	3	no	6.205	5.860	PhosphoSitePlus;EPSD	COSMIC	1.932	Down-regulation
CMGC_CDK_CDK9_CDK9_ST	P84022	SMAD3	P50750	CDK9	S208	P209S	209	Missense	proximal	1	no	6.205	2.471	PhosphoSitePlus;EPSD	COSMIC	1.932	Down-regulation
CMGC_CDK_CDK9_CDK9_ST	P84022	SMAD3	P50750	CDK9	S213	P211S	211	Missense	proximal	-2	no	5.861	5.622	EPSD;PhosphoSitePlus	COSMIC	1.932	Down-regulation
CMGC_CDK_CDK9_CDK9_ST	P84022	SMAD3	P50750	CDK9	S213	P211L	211	Missense	proximal	-2	no	5.861	5.072	EPSD;PhosphoSitePlus	COSMIC	1.932	Down-regulation
CMGC_CDK_CDK9_CDK9_ST	P84022	SMAD3	P50750	CDK9	S213	P209S	209	Missense	distal	-4	no	5.861	5.881	EPSD;PhosphoSitePlus	COSMIC	1.932	Up-regulation
CMGC_CDK_CDK9_CDK9_ST	P84022	SMAD3	P50750	CDK9	T286	R287P	287	Missense	proximal	1	no	0.833	5.009	EPSD	COSMIC	1.932	Gain
CMGC_CDK_CDK9_CDK9_ST	P84022	SMAD3	P50750	CDK9	T412	D408Y	408	Missense	distal	-4	no	2.233	2.242	EPSD	COSMIC	1.932	Up-regulation
CMGC_CDK_CDK9_CDK9_ST	P84022	SMAD3	P50750	CDK9	T412	L407P	407	Missense	distal	-5	no	2.233	2.612	EPSD	COSMIC	1.932	Up-regulation
CMGC_CDK_CDK9_CDK9_ST	P84022	SMAD3	P50750	CDK9	T412	V410I	410	Missense	proximal	-2	no	2.233	2.162	EPSD	COSMIC	1.932	Down-regulation
CMGC_CDK_CDK9_CDK9_ST	P84022	SMAD3	P50750	CDK9	S416	S423G	423	Missense	distal	7	no	5.181	5.451	EPSD	COSMIC	1.932	Up-regulation
CMGC_CDK_CDK9_CDK9_ST	P84022	SMAD3	P50750	CDK9	S416	S423I	423	Missense	distal	7	no	5.181	5.469	EPSD	COSMIC	1.932	Up-regulation
CMGC_CDK_CDK9_CDK9_ST	P84022	SMAD3	P50750	CDK9	S416	V410I	410	Missense	distal	-6	no	5.181	5.135	EPSD	COSMIC	1.932	Down-regulation
CMGC_CDK_CDK9_CDK9_ST	P84022	SMAD3	P50750	CDK9	S416	S422Y	422	Missense	distal	6	no	5.181	4.631	EPSD	COSMIC	1.932	Down-regulation
CMGC_CDK_CDK9_CDK9_ST	P84022	SMAD3	P50750	CDK9	S416	C421Y	421	Missense	distal	5	no	5.181	5.266	EPSD	COSMIC	1.932	Up-regulation
CMGC_CDK_CDK9_CDK9_ST	P84022	SMAD3	P50750	CDK9	S416	R420C	420	Missense	distal	4	no	5.181	5.140	EPSD	COSMIC	1.932	Down-regulation
CMGC_CDK_CDK9_CDK9_ST	P84022	SMAD3	P50750	CDK9	S422	S423G	423	Missense	proximal	1	no	2.348	0.610	EPSD	COSMIC	1.932	Loss
CMGC_CDK_CDK9_CDK9_ST	P84022	SMAD3	P50750	CDK9	S422	S423I	423	Missense	proximal	1	no	2.348	0.934	EPSD	COSMIC	1.932	Loss
CMGC_CDK_CDK9_CDK9_ST	P84022	SMAD3	P50750	CDK9	S422	S422Y	422	Missense	central	0	yes	2.348	0.000	EPSD	COSMIC	1.932	Loss
CMGC_CDK_CDK9_CDK9_ST	P84022	SMAD3	P50750	CDK9	S422	C421Y	421	Missense	proximal	-1	no	2.348	2.353	EPSD	COSMIC	1.932	Up-regulation
CMGC_CDK_CDK9_CDK9_ST	P84022	SMAD3	P50750	CDK9	S422	R420C	420	Missense	proximal	-2	no	2.348	2.140	EPSD	COSMIC	1.932	Down-regulation
CMGC_CDK_CDK9_CDK9_ST	P24928	POLR2A	P50750	CDK9	S27	G24R	24	Missense	distal	-3	no	4.480	4.464	EPSD	COSMIC	1.932	Down-regulation
CMGC_CDK_CDK9_CDK9_ST	P24928	POLR2A	P50750	CDK9	S27	R33Q	33	Missense	distal	6	no	4.480	4.724	EPSD	COSMIC;CCLE	1.932	Up-regulation
CMGC_CDK_CDK9_CDK9_ST	P24928	POLR2A	P50750	CDK9	S27	G24A	24	Missense	distal	-3	no	4.480	4.486	EPSD	COSMIC	1.932	Up-regulation
CMGC_CDK_CDK9_CDK9_ST	P24928	POLR2A	P50750	CDK9	T46	R51C	51	Missense	distal	5	no	1.956	1.812	EPSD	COSMIC	1.932	Loss
CMGC_CDK_CDK9_CDK9_ST	P24928	POLR2A	P50750	CDK9	T46	P44S	44	Missense	proximal	-2	no	1.956	1.717	EPSD	COSMIC	1.932	Loss
CMGC_CDK_CDK9_CDK9_ST	P24928	POLR2A	P50750	CDK9	T46	R51H	51	Missense	distal	5	no	1.956	1.919	EPSD	COSMIC	1.932	Loss
CMGC_CDK_CDK9_CDK9_ST	P24928	POLR2A	P50750	CDK9	S217	E219V	219	Missense	proximal	2	no	5.452	5.482	EPSD	COSMIC	1.932	Up-regulation
CMGC_CDK_CDK9_CDK9_ST	P24928	POLR2A	P50750	CDK9	T368	T365I	365	Missense	distal	-3	no	6.146	6.174	EPSD	COSMIC	1.932	Up-regulation
CMGC_CDK_CDK9_CDK9_ST	P24928	POLR2A	P50750	CDK9	T368	R364C	364	Missense	distal	-4	no	6.146	6.096	EPSD	COSMIC	1.932	Down-regulation
CMGC_CDK_CDK9_CDK9_ST	P24928	POLR2A	P50750	CDK9	S530	R532L	532	Missense	proximal	2	no	2.911	2.970	EPSD	COSMIC	1.932	Up-regulation
CMGC_CDK_CDK9_CDK9_ST	Q6PGQ7	BORA	P50750	CDK9	S112	P113A	113	Missense	proximal	1	no	3.786	-1.378	EPSD	COSMIC	1.932	Loss
CMGC_CDK_CDK9_CDK9_ST	Q6PGQ7	BORA	P50750	CDK9	S268	S270L	270	Missense	proximal	2	no	5.318	5.521	EPSD	COSMIC	1.932	Up-regulation
CMGC_CDK_CDK9_CDK9_ST	Q6PGQ7	BORA	P50750	CDK9	S268	S270T	270	Missense	proximal	2	no	5.318	5.436	EPSD	COSMIC	1.932	Up-regulation
CMGC_CDK_CDK9_CDK9_ST	Q6PGQ7	BORA	P50750	CDK9	S270	S270L	270	Missense	central	0	yes	6.009	0.000	EPSD	COSMIC	1.932	Loss
CMGC_CDK_CDK9_CDK9_ST	Q6PGQ7	BORA	P50750	CDK9	S270	T276A	276	Missense	distal	6	no	6.009	5.824	EPSD	COSMIC	1.932	Down-regulation
CMGC_CDK_CDK9_CDK9_ST	Q6PGQ7	BORA	P50750	CDK9	S273	S270L	270	Missense	distal	-3	no	2.776	2.866	EPSD	COSMIC	1.932	Up-regulation
CMGC_CDK_CDK9_CDK9_ST	Q6PGQ7	BORA	P50750	CDK9	S273	S270T	270	Missense	distal	-3	no	2.776	2.831	EPSD	COSMIC	1.932	Up-regulation
CMGC_CDK_CDK9_CDK9_ST	Q6PGQ7	BORA	P50750	CDK9	S273	T276A	276	Missense	distal	3	no	2.776	2.689	EPSD	COSMIC	1.932	Down-regulation
CMGC_CDK_CDK9_CDK9_ST	Q6PGQ7	BORA	P50750	CDK9	S274	S270L	270	Missense	distal	-4	no	4.856	4.701	EPSD	COSMIC	1.932	Down-regulation
CMGC_CDK_CDK9_CDK9_ST	Q6PGQ7	BORA	P50750	CDK9	S274	S270T	270	Missense	distal	-4	no	4.856	4.761	EPSD	COSMIC	1.932	Down-regulation
CMGC_CDK_CDK9_CDK9_ST	Q6PGQ7	BORA	P50750	CDK9	S274	T276A	276	Missense	proximal	2	no	4.856	4.930	EPSD	COSMIC	1.932	Up-regulation
CMGC_CDK_CDK9_CDK9_ST	Q6PGQ7	BORA	P50750	CDK9	S278	T276A	276	Missense	proximal	-2	no	4.887	4.679	EPSD	COSMIC	1.932	Down-regulation
CMGC_CDK_CDK9_CDK9_ST	Q9H0D6	XRN2	P50750	CDK9	T439	A442T	442	Missense	distal	3	no	5.819	5.907	PhosphoSitePlus	COSMIC;GDSC;CCLE	1.932	Up-regulation
CMGC_CDK_CDK9_CDK9_ST	Q9H0D6	XRN2	P50750	CDK9	T439	R446S	446	Missense	distal	7	no	5.819	5.591	PhosphoSitePlus	COSMIC	1.932	Down-regulation
CMGC_CDK_CDK9_CDK9_ST	Q9H0D6	XRN2	P50750	CDK9	S448	A442T	442	Missense	distal	-6	no	2.947	3.109	EPSD	COSMIC;GDSC;CCLE	1.932	Up-regulation
CMGC_CDK_CDK9_CDK9_ST	Q9H0D6	XRN2	P50750	CDK9	S448	R446S	446	Missense	proximal	-2	no	2.947	3.265	EPSD	COSMIC	1.932	Up-regulation
CMGC_CDK_CDK9_CDK9_ST	Q9H0D6	XRN2	P50750	CDK9	S451	R446S	446	Missense	distal	-5	no	1.622	1.951	EPSD	COSMIC	1.932	Gain
CMGC_CDK_CDK9_CDK9_ST	Q9H0D6	XRN2	P50750	CDK9	S471	S473L	473	Missense	proximal	2	no	4.531	4.734	EPSD	COSMIC	1.932	Up-regulation
CMGC_CDK_CDK9_CDK9_ST	Q9H0D6	XRN2	P50750	CDK9	S471	R465M	465	Missense	distal	-6	no	4.531	4.477	EPSD	COSMIC;CCLE	1.932	Down-regulation
CMGC_CDK_CDK9_CDK9_ST	Q9H0D6	XRN2	P50750	CDK9	S471	T478P	478	Missense	distal	7	no	4.531	4.375	EPSD	COSMIC	1.932	Down-regulation
CMGC_CDK_CDK9_CDK9_ST	Q9H0D6	XRN2	P50750	CDK9	S471	S470Y	470	Missense	proximal	-1	no	4.531	4.457	EPSD	COSMIC	1.932	Down-regulation
CMGC_CDK_CDK9_CDK9_ST	Q9H0D6	XRN2	P50750	CDK9	S475	S473L	473	Missense	proximal	-2	no	5.832	5.282	EPSD	COSMIC	1.932	Down-regulation
CMGC_CDK_CDK9_CDK9_ST	Q9H0D6	XRN2	P50750	CDK9	S475	T478P	478	Missense	distal	3	no	5.832	6.046	EPSD	COSMIC	1.932	Up-regulation
CMGC_CDK_CDK9_CDK9_ST	Q9H0D6	XRN2	P50750	CDK9	S475	S479T	479	Missense	distal	4	no	5.832	5.740	EPSD	COSMIC	1.932	Down-regulation
CMGC_CDK_CDK9_CDK9_ST	Q9H0D6	XRN2	P50750	CDK9	S475	S470Y	470	Missense	distal	-5	no	5.832	5.431	EPSD	COSMIC	1.932	Down-regulation
CMGC_CDK_CDK9_CDK9_ST	Q9H0D6	XRN2	P50750	CDK9	S475	S479R	479	Missense	distal	4	no	5.832	5.717	EPSD	COSMIC	1.932	Down-regulation
CMGC_CDK_CDK9_CDK9_ST	Q9H0D6	XRN2	P50750	CDK9	T481	P486L	486	Missense	distal	5	no	2.301	1.976	EPSD	COSMIC	1.932	Down-regulation
CMGC_CDK_CDK9_CDK9_ST	Q9H0D6	XRN2	P50750	CDK9	T481	T478P	478	Missense	distal	-3	no	2.301	2.251	EPSD	COSMIC	1.932	Down-regulation
CMGC_CDK_CDK9_CDK9_ST	Q9H0D6	XRN2	P50750	CDK9	T481	S479T	479	Missense	proximal	-2	no	2.301	2.048	EPSD	COSMIC	1.932	Down-regulation
CMGC_CDK_CDK9_CDK9_ST	Q9H0D6	XRN2	P50750	CDK9	T481	S479R	479	Missense	proximal	-2	no	2.301	1.984	EPSD	COSMIC	1.932	Down-regulation
CMGC_CDK_CDK9_CDK9_ST	Q9H0D6	XRN2	P50750	CDK9	S485	P486L	486	Missense	proximal	1	no	4.367	-1.231	EPSD	COSMIC	1.932	Loss
CMGC_CDK_CDK9_CDK9_ST	Q9H0D6	XRN2	P50750	CDK9	S485	T478P	478	Missense	distal	-7	no	4.367	4.328	EPSD	COSMIC	1.932	Down-regulation
CMGC_CDK_CDK9_CDK9_ST	Q9H0D6	XRN2	P50750	CDK9	S485	S479T	479	Missense	distal	-6	no	4.367	4.133	EPSD	COSMIC	1.932	Down-regulation
CMGC_CDK_CDK9_CDK9_ST	Q9H0D6	XRN2	P50750	CDK9	S485	S479R	479	Missense	distal	-6	no	4.367	4.080	EPSD	COSMIC	1.932	Down-regulation
CMGC_CDK_CDK9_CDK9_ST	Q9H0D6	XRN2	P50750	CDK9	S487	P486L	486	Missense	proximal	-1	no	6.247	6.210	EPSD	COSMIC	1.932	Down-regulation
CMGC_CDK_CDK9_CDK9_ST	Q9H0D6	XRN2	P50750	CDK9	T670	P667Q	667	Missense	distal	-3	no	4.198	4.236	EPSD	COSMIC	1.932	Up-regulation
CMGC_CDK_CDK9_CDK9_ST	Q9H0D6	XRN2	P50750	CDK9	T670	P671A	671	Missense	proximal	1	no	4.198	-0.966	EPSD	COSMIC	1.932	Loss
CMGC_CDK_CDK9_CDK9_ST	Q9H0D6	XRN2	P50750	CDK9	S790	K796M	796	Missense	distal	6	no	2.214	2.106	EPSD	COSMIC	1.932	Down-regulation
CMGC_CDK_CDK9_CDK9_ST	Q9H0D6	XRN2	P50750	CDK9	S790	D785Y	785	Missense	distal	-5	no	2.214	2.258	EPSD	COSMIC	1.932	Up-regulation
CMGC_CDK_CDK9_CDK9_ST	Q9H0D6	XRN2	P50750	CDK9	S832	S832C	832	Missense	central	0	yes	2.062	0.000	EPSD	COSMIC	1.932	Loss
CMGC_CDK_CDK9_CDK9_ST	Q9H0D6	XRN2	P50750	CDK9	S861	M863I	863	Missense	proximal	2	no	2.157	2.179	EPSD	COSMIC	1.932	Up-regulation
CMGC_CDK_CDK9_CDK9_ST	P37231	PPARG	P50750	CDK9	S273	D271E	271	Missense	proximal	-2	no	4.027	4.155	EPSD	COSMIC	1.932	Up-regulation
CMGC_CDK_CDK9_CDK9_ST	P10275	AR	P50750	CDK9	S83	Q79E	79	Missense	distal	-4	no	6.017	5.956	PhosphoSitePlus	COSMIC	1.932	Down-regulation
CMGC_CDK_CDK9_CDK9_ST	P10275	AR	P50750	CDK9	S83	Q86K	86	Missense	distal	3	no	6.017	5.934	PhosphoSitePlus	COSMIC	1.932	Down-regulation
CMGC_CDK_CDK9_CDK9_ST	P10275	AR	P50750	CDK9	S83	E81Q	81	Missense	proximal	-2	no	6.017	6.237	PhosphoSitePlus	COSMIC	1.932	Up-regulation
CMGC_CDK_CDK9_CDK9_ST	P10275	AR	P50750	CDK9	S83	Q90H	90	Missense	distal	7	no	6.017	6.136	PhosphoSitePlus	COSMIC	1.932	Up-regulation
CMGC_CDK_CDK9_CDK9_ST	P10275	AR	P50750	CDK9	S83	Q79R	79	Missense	distal	-4	no	6.017	5.959	PhosphoSitePlus	COSMIC	1.932	Down-regulation
CMGC_CDK_CDK9_CDK9_ST	P10275	AR	P50750	CDK9	S83	P84H	84	Missense	proximal	1	no	6.017	1.443	PhosphoSitePlus	COSMIC	1.932	Loss
CMGC_CDK_CDK9_CDK9_ST	P10275	AR	P50750	CDK9	S96	S96Y	96	Missense	central	0	yes	4.065	0.000	EPSD	COSMIC	1.932	Loss
CMGC_CDK_CDK9_CDK9_ST	P10275	AR	P50750	CDK9	S96	Q90H	90	Missense	distal	-6	no	4.065	3.855	EPSD	COSMIC	1.932	Down-regulation
CMGC_CDK_CDK9_CDK9_ST	P10275	AR	P50750	CDK9	S96	S96F	96	Missense	central	0	yes	4.065	0.000	EPSD	COSMIC	1.932	Loss
CMGC_CDK_CDK9_CDK9_ST	P10275	AR	P50750	CDK9	S258	L257P	257	Missense	proximal	-1	no	4.086	4.124	EPSD	COSMIC	1.932	Up-regulation
CMGC_CDK_CDK9_CDK9_ST	P10275	AR	P50750	CDK9	S258	R264Q	264	Missense	distal	6	no	4.086	4.330	EPSD	COSMIC	1.932	Up-regulation
CMGC_CDK_CDK9_CDK9_ST	P10275	AR	P50750	CDK9	S258	E252G	252	Missense	distal	-6	no	4.086	4.011	EPSD	COSMIC	1.932	Down-regulation
CMGC_CDK_CDK9_CDK9_ST	P10275	AR	P50750	CDK9	S258	E252K	252	Missense	distal	-6	no	4.086	4.148	EPSD	COSMIC	1.932	Up-regulation
CMGC_CDK_CDK9_CDK9_ST	P10275	AR	P50750	CDK9	S258	E255K	255	Missense	distal	-3	no	4.086	4.080	EPSD	COSMIC	1.932	Down-regulation
CMGC_CDK_CDK9_CDK9_ST	P10275	AR	P50750	CDK9	T282	R280H	280	Missense	proximal	-2	no	4.856	4.784	EPSD	COSMIC	1.932	Down-regulation
CMGC_CDK_CDK9_CDK9_ST	P10275	AR	P50750	CDK9	T282	E289G	289	Missense	distal	7	no	4.856	4.896	EPSD	COSMIC	1.932	Up-regulation
CMGC_CDK_CDK9_CDK9_ST	P10275	AR	P50750	CDK9	T282	P276S	276	Missense	distal	-6	no	4.856	4.724	EPSD	COSMIC	1.932	Down-regulation
CMGC_CDK_CDK9_CDK9_ST	P10275	AR	P50750	CDK9	T282	P283S	283	Missense	proximal	1	no	4.856	1.122	EPSD	COSMIC	1.932	Loss
CMGC_CDK_CDK9_CDK9_ST	P10275	AR	P50750	CDK9	T282	A278T	278	Missense	distal	-4	no	4.856	4.906	EPSD	COSMIC	1.932	Up-regulation
CMGC_CDK_CDK9_CDK9_ST	P10275	AR	P50750	CDK9	T282	A285D	285	Missense	distal	3	no	4.856	4.844	EPSD	COSMIC	1.932	Down-regulation
CMGC_CDK_CDK9_CDK9_ST	P10275	AR	P50750	CDK9	T282	A285V	285	Missense	distal	3	no	4.856	4.870	EPSD	COSMIC	1.932	Up-regulation
CMGC_CDK_CDK9_CDK9_ST	P10275	AR	P50750	CDK9	S310	D305N	305	Missense	distal	-5	no	4.651	4.867	EPSD	COSMIC	1.932	Up-regulation
CMGC_CDK_CDK9_CDK9_ST	P10275	AR	P50750	CDK9	S310	S310F	310	Missense	central	0	yes	4.651	0.000	EPSD	COSMIC	1.932	Loss
CMGC_CDK_CDK9_CDK9_ST	P10275	AR	P50750	CDK9	S310	E304K	304	Missense	distal	-6	no	4.651	4.713	EPSD	COSMIC	1.932	Up-regulation
CMGC_CDK_CDK9_CDK9_ST	P10275	AR	P50750	CDK9	S310	T306I	306	Missense	distal	-4	no	4.651	4.604	EPSD	COSMIC;GDSC;CCLE	1.932	Down-regulation
CMGC_CDK_CDK9_CDK9_ST	P10275	AR	P50750	CDK9	S426	A430T	430	Missense	distal	4	no	4.924	4.958	EPSD	COSMIC	1.932	Up-regulation
CMGC_CDK_CDK9_CDK9_ST	P10275	AR	P50750	CDK9	S426	A420E	420	Missense	distal	-6	no	4.924	5.025	EPSD	COSMIC	1.932	Up-regulation
CMGC_CDK_CDK9_CDK9_ST	P10275	AR	P50750	CDK9	S426	G421V	421	Missense	distal	-5	no	4.924	4.862	EPSD	COSMIC	1.932	Down-regulation
CMGC_CDK_CDK9_CDK9_ST	P10275	AR	P50750	CDK9	S426	A430S	430	Missense	distal	4	no	4.924	5.050	EPSD	COSMIC	1.932	Up-regulation
CMGC_CDK_CDK9_CDK9_ST	P10275	AR	P50750	CDK9	S426	G421R	421	Missense	distal	-5	no	4.924	4.957	EPSD	COSMIC	1.932	Up-regulation
CMGC_CDK_CDK9_CDK9_ST	P10275	AR	P50750	CDK9	S426	S433L	433	Missense	distal	7	no	4.924	5.225	EPSD	COSMIC	1.932	Up-regulation
CMGC_CDK_CDK9_CDK9_ST	P10275	AR	P50750	CDK9	S426	S424C	424	Missense	proximal	-2	no	4.924	4.398	EPSD	COSMIC	1.932	Down-regulation
CMGC_CDK_CDK9_CDK9_ST	P10275	AR	P50750	CDK9	S426	S424F	424	Missense	proximal	-2	no	4.924	4.405	EPSD	COSMIC	1.932	Down-regulation
CMGC_CDK_CDK9_CDK9_ST	P10275	AR	P50750	CDK9	S516	P515H	515	Missense	proximal	-1	no	5.379	5.356	EPSD	COSMIC	1.932	Down-regulation
CMGC_CDK_CDK9_CDK9_ST	P10275	AR	P50750	CDK9	S516	E523K	523	Missense	distal	7	no	5.379	5.361	EPSD	COSMIC	1.932	Down-regulation
CMGC_CDK_CDK9_CDK9_ST	P10275	AR	P50750	CDK9	S516	P515S	515	Missense	proximal	-1	no	5.379	5.416	EPSD	COSMIC	1.932	Up-regulation
CMGC_CDK_CDK9_CDK9_ST	P10275	AR	P50750	CDK9	S651	A646D	646	Missense	distal	-5	no	4.953	4.926	EPSD	COSMIC	1.932	Down-regulation
CMGC_CDK_CDK9_CDK9_ST	P10275	AR	P50750	CDK9	S651	S648R	648	Missense	distal	-3	no	4.953	5.019	EPSD	COSMIC	1.932	Up-regulation
CMGC_CDK_CDK9_CDK9_ST	P10275	AR	P50750	CDK9	S651	S648N	648	Missense	distal	-3	no	4.953	4.994	EPSD	COSMIC	1.932	Up-regulation
CMGC_CDK_CDK9_CDK9_ST	P10275	AR	P50750	CDK9	S651	E654K	654	Missense	distal	3	no	4.953	5.015	EPSD	COSMIC	1.932	Up-regulation
CMGC_CDK_CDK9_CDK9_ST	P10275	AR	P50750	CDK9	S651	S647F	647	Missense	distal	-4	no	4.953	4.788	EPSD	COSMIC	1.932	Down-regulation
CMGC_CDK_CDK9_CDK9_ST	P10275	AR	P50750	CDK9	S651	E655D	655	Missense	distal	4	no	4.953	4.922	EPSD	COSMIC	1.932	Down-regulation
CMGC_CDK_CDK9_CDK9_ST	P10275	AR	P50750	CDK9	T653	A646D	646	Missense	distal	-7	no	2.171	2.170	EPSD	COSMIC	1.932	Down-regulation
CMGC_CDK_CDK9_CDK9_ST	P10275	AR	P50750	CDK9	T653	S648R	648	Missense	distal	-5	no	2.171	1.842	EPSD	COSMIC	1.932	Loss
CMGC_CDK_CDK9_CDK9_ST	P10275	AR	P50750	CDK9	T653	S648N	648	Missense	distal	-5	no	2.171	1.941	EPSD	COSMIC	1.932	Down-regulation
CMGC_CDK_CDK9_CDK9_ST	P10275	AR	P50750	CDK9	T653	E654K	654	Missense	proximal	1	no	2.171	2.452	EPSD	COSMIC	1.932	Up-regulation
CMGC_CDK_CDK9_CDK9_ST	P10275	AR	P50750	CDK9	T653	K659N	659	Missense	distal	6	no	2.171	2.323	EPSD	COSMIC	1.932	Up-regulation
CMGC_CDK_CDK9_CDK9_ST	P10275	AR	P50750	CDK9	T653	S647F	647	Missense	distal	-6	no	2.171	1.733	EPSD	COSMIC	1.932	Loss
CMGC_CDK_CDK9_CDK9_ST	P10275	AR	P50750	CDK9	T653	E655D	655	Missense	proximal	2	no	2.171	2.222	EPSD	COSMIC	1.932	Up-regulation
CMGC_CDK_CDK9_CDK9_ST	P10275	AR	P50750	CDK9	T657	V662A	662	Missense	distal	5	no	2.642	2.670	EPSD	COSMIC	1.932	Up-regulation
CMGC_CDK_CDK9_CDK9_ST	P10275	AR	P50750	CDK9	T657	E654K	654	Missense	distal	-3	no	2.642	2.637	EPSD	COSMIC	1.932	Down-regulation
CMGC_CDK_CDK9_CDK9_ST	P10275	AR	P50750	CDK9	T657	K659N	659	Missense	proximal	2	no	2.642	2.627	EPSD	COSMIC	1.932	Down-regulation
CMGC_CDK_CDK9_CDK9_ST	P10275	AR	P50750	CDK9	T657	S663L	663	Missense	distal	6	no	2.642	2.006	EPSD	COSMIC	1.932	Down-regulation
CMGC_CDK_CDK9_CDK9_ST	P10275	AR	P50750	CDK9	T657	E655D	655	Missense	proximal	-2	no	2.642	2.515	EPSD	COSMIC	1.932	Down-regulation
CMGC_CDK_CDK9_CDK9_ST	Q15596	NCOA2	P50750	CDK9	S400	S399G	399	Missense	proximal	-1	no	2.325	2.262	EPSD	COSMIC	1.932	Down-regulation
CMGC_CDK_CDK9_CDK9_ST	Q15596	NCOA2	P50750	CDK9	S400	L395P	395	Missense	distal	-5	no	2.325	2.704	EPSD	COSMIC	1.932	Up-regulation
CMGC_CDK_CDK9_CDK9_ST	Q15596	NCOA2	P50750	CDK9	S402	S399G	399	Missense	distal	-3	no	4.947	5.028	EPSD	COSMIC	1.932	Up-regulation
CMGC_CDK_CDK9_CDK9_ST	Q15596	NCOA2	P50750	CDK9	S402	L395P	395	Missense	distal	-7	no	4.947	4.880	EPSD	COSMIC	1.932	Down-regulation
CMGC_CDK_CDK9_CDK9_ST	Q15596	NCOA2	P50750	CDK9	T456	P458T	458	Missense	proximal	2	no	1.866	1.946	EPSD	COSMIC;GDSC;CCLE	1.932	Gain
CMGC_CDK_CDK9_CDK9_ST	Q15596	NCOA2	P50750	CDK9	T457	P458T	458	Missense	proximal	1	no	5.049	1.030	EPSD	COSMIC;GDSC;CCLE	1.932	Loss
CMGC_CDK_CDK9_CDK9_ST	Q15596	NCOA2	P50750	CDK9	S469	S473T	473	Missense	distal	4	no	5.622	5.530	EPSD;PhosphoSitePlus	COSMIC	1.932	Down-regulation
CMGC_CDK_CDK9_CDK9_ST	Q15596	NCOA2	P50750	CDK9	S469	M467I	467	Missense	proximal	-2	no	5.622	5.534	EPSD;PhosphoSitePlus	COSMIC	1.932	Down-regulation
CMGC_CDK_CDK9_CDK9_ST	Q15596	NCOA2	P50750	CDK9	S469	P470S	470	Missense	proximal	1	no	5.622	1.888	EPSD;PhosphoSitePlus	COSMIC;GDSC;CCLE	1.932	Loss
CMGC_CDK_CDK9_CDK9_ST	Q15596	NCOA2	P50750	CDK9	S474	S473T	473	Missense	proximal	-1	no	4.946	4.897	EPSD	COSMIC	1.932	Down-regulation
CMGC_CDK_CDK9_CDK9_ST	Q15596	NCOA2	P50750	CDK9	S474	M467I	467	Missense	distal	-7	no	4.946	4.955	EPSD	COSMIC	1.932	Up-regulation
CMGC_CDK_CDK9_CDK9_ST	Q15596	NCOA2	P50750	CDK9	S474	P470S	470	Missense	distal	-4	no	4.946	4.966	EPSD	COSMIC;GDSC;CCLE	1.932	Up-regulation
CMGC_CDK_CDK9_CDK9_ST	Q15596	NCOA2	P50750	CDK9	S474	G480R	480	Missense	distal	6	no	4.946	4.998	EPSD	COSMIC	1.932	Up-regulation
CMGC_CDK_CDK9_CDK9_ST	Q15596	NCOA2	P50750	CDK9	S487	G480R	480	Missense	distal	-7	no	5.333	5.323	EPSD;PhosphoSitePlus	COSMIC	1.932	Down-regulation
CMGC_CDK_CDK9_CDK9_ST	Q15596	NCOA2	P50750	CDK9	S565	V567F	567	Missense	proximal	2	no	4.997	5.032	EPSD	COSMIC;GDSC;CCLE	1.932	Up-regulation
CMGC_CDK_CDK9_CDK9_ST	Q15596	NCOA2	P50750	CDK9	S655	S662L	662	Missense	distal	7	no	4.793	5.094	EPSD	COSMIC	1.932	Up-regulation
CMGC_CDK_CDK9_CDK9_ST	Q15596	NCOA2	P50750	CDK9	S655	P656S	656	Missense	proximal	1	no	4.793	1.059	EPSD	COSMIC	1.932	Loss
CMGC_CDK_CDK9_CDK9_ST	Q15596	NCOA2	P50750	CDK9	S659	S662L	662	Missense	distal	3	no	2.087	1.776	EPSD	COSMIC	1.932	Loss
CMGC_CDK_CDK9_CDK9_ST	Q15596	NCOA2	P50750	CDK9	S659	P656S	656	Missense	distal	-3	no	2.087	2.082	EPSD	COSMIC	1.932	Down-regulation
CMGC_CDK_CDK9_CDK9_ST	Q15596	NCOA2	P50750	CDK9	T664	S662L	662	Missense	proximal	-2	no	2.878	2.328	EPSD	COSMIC	1.932	Down-regulation
CMGC_CDK_CDK9_CDK9_ST	Q15596	NCOA2	P50750	CDK9	T664	G670S	670	Missense	distal	6	no	2.878	3.389	EPSD	COSMIC	1.932	Up-regulation
CMGC_CDK_CDK9_CDK9_ST	Q15596	NCOA2	P50750	CDK9	S736	P737S	737	Missense	proximal	1	no	5.598	1.864	EPSD	COSMIC	1.932	Loss
CMGC_CDK_CDK9_CDK9_ST	Q15596	NCOA2	P50750	CDK9	T763	D756V	756	Missense	distal	-7	no	4.624	4.621	EPSD	COSMIC	1.932	Down-regulation
CMGC_CDK_CDK9_CDK9_ST	Q15596	NCOA2	P50750	CDK9	S851	A848V	848	Missense	distal	-3	no	4.095	4.087	EPSD	COSMIC	1.932	Down-regulation
CMGC_CDK_CDK9_CDK9_ST	Q15596	NCOA2	P50750	CDK9	S851	E849K	849	Missense	proximal	-2	no	4.095	4.164	EPSD	COSMIC	1.932	Up-regulation
CMGC_CDK_CDK9_CDK9_ST	Q15596	NCOA2	P50750	CDK9	S851	G857A	857	Missense	distal	6	no	4.095	4.057	EPSD	COSMIC	1.932	Down-regulation
CMGC_CDK_CDK9_CDK9_ST	Q15596	NCOA2	P50750	CDK9	T854	A848V	848	Missense	distal	-6	no	6.136	6.172	EPSD	COSMIC	1.932	Up-regulation
CMGC_CDK_CDK9_CDK9_ST	Q15596	NCOA2	P50750	CDK9	T854	E849K	849	Missense	distal	-5	no	6.136	6.194	EPSD	COSMIC	1.932	Up-regulation
CMGC_CDK_CDK9_CDK9_ST	Q15596	NCOA2	P50750	CDK9	T854	G857A	857	Missense	distal	3	no	6.136	6.121	EPSD	COSMIC	1.932	Down-regulation
CMGC_CDK_CDK9_CDK9_ST	Q15596	NCOA2	P50750	CDK9	S895	T897A	897	Missense	proximal	2	no	5.047	5.122	EPSD	COSMIC;CCLE	1.932	Up-regulation
CMGC_CDK_CDK9_CDK9_ST	Q15596	NCOA2	P50750	CDK9	S1059	L1064P	1064	Missense	distal	5	no	5.295	5.620	EPSD	COSMIC;CCLE	1.932	Up-regulation
CMGC_CDK_CDK9_CDK9_ST	Q15596	NCOA2	P50750	CDK9	S1059	P1055L	1055	Missense	distal	-4	no	5.295	5.161	EPSD	COSMIC	1.932	Down-regulation
CMGC_CDK_CDK9_CDK9_ST	Q15596	NCOA2	P50750	CDK9	S1072	H1067R	1067	Missense	distal	-5	no	5.249	5.279	EPSD	COSMIC;GDSC;CCLE	1.932	Up-regulation
CMGC_CDK_CDK9_CDK9_ST	Q15596	NCOA2	P50750	CDK9	S1072	P1073Q	1073	Missense	proximal	1	no	5.249	1.694	EPSD	COSMIC	1.932	Loss
CMGC_CDK_CDK9_CDK9_ST	Q15596	NCOA2	P50750	CDK9	S1211	L1206R	1206	Missense	distal	-5	no	2.248	2.383	EPSD	COSMIC	1.932	Up-regulation
CMGC_CDK_CDK9_CDK9_ST	Q15596	NCOA2	P50750	CDK9	S1211	N1215S	1215	Missense	distal	4	no	2.248	2.331	EPSD	COSMIC	1.932	Up-regulation
CMGC_CDK_CDK9_CDK9_ST	Q15596	NCOA2	P50750	CDK9	S1211	S1211N	1211	Missense	central	0	yes	2.248	0.000	EPSD	COSMIC;GDSC;CCLE	1.932	Loss
CMGC_CDK_CDK9_CDK9_ST	Q15596	NCOA2	P50750	CDK9	T1273	G1269W	1269	Missense	distal	-4	no	4.922	4.878	EPSD	COSMIC	1.932	Down-regulation
CMGC_CDK_CDK9_CDK9_ST	P06400	RB1	P50750	CDK9	T5	P6S	6	Missense	proximal	1	no	4.174	0.439	EPSD	COSMIC	1.932	Loss
CMGC_CDK_CDK9_CDK9_ST	P06400	RB1	P50750	CDK9	T5	P2S	2	Missense	distal	-3	no	4.174	4.169	EPSD	COSMIC	1.932	Down-regulation
CMGC_CDK_CDK9_CDK9_ST	P06400	RB1	P50750	CDK9	T5	T5N	5	Missense	central	0	yes	4.174	0.000	EPSD	COSMIC	1.932	Loss
CMGC_CDK_CDK9_CDK9_ST	P06400	RB1	P50750	CDK9	T5	R7Q	7	Missense	proximal	2	no	4.174	4.127	EPSD	COSMIC	1.932	Down-regulation
CMGC_CDK_CDK9_CDK9_ST	P06400	RB1	P50750	CDK9	S230	K228R	228	Missense	proximal	-2	no	3.314	3.259	EPSD	COSMIC;GDSC;CCLE	1.932	Down-regulation
CMGC_CDK_CDK9_CDK9_ST	P06400	RB1	P50750	CDK9	S230	I227N	227	Missense	distal	-3	no	3.314	3.273	EPSD	COSMIC	1.932	Down-regulation
CMGC_CDK_CDK9_CDK9_ST	P06400	RB1	P50750	CDK9	S230	P232L	232	Missense	proximal	2	no	3.314	3.479	EPSD	COSMIC	1.932	Up-regulation
CMGC_CDK_CDK9_CDK9_ST	P06400	RB1	P50750	CDK9	S249	V243A	243	Missense	distal	-6	no	5.182	5.146	EPSD	COSMIC	1.932	Down-regulation
CMGC_CDK_CDK9_CDK9_ST	P06400	RB1	P50750	CDK9	S249	P250S	250	Missense	proximal	1	no	5.182	1.448	EPSD	COSMIC	1.932	Loss
CMGC_CDK_CDK9_CDK9_ST	P06400	RB1	P50750	CDK9	T252	Q257R	257	Missense	distal	5	no	5.473	5.296	EPSD	COSMIC	1.932	Down-regulation
CMGC_CDK_CDK9_CDK9_ST	P06400	RB1	P50750	CDK9	T252	P250S	250	Missense	proximal	-2	no	5.473	5.234	EPSD	COSMIC	1.932	Down-regulation
CMGC_CDK_CDK9_CDK9_ST	P06400	RB1	P50750	CDK9	T356	E352K	352	Missense	distal	-4	no	4.712	4.726	EPSD	COSMIC	1.932	Up-regulation
CMGC_CDK_CDK9_CDK9_ST	P06400	RB1	P50750	CDK9	T356	R358Q	358	Missense	proximal	2	no	4.712	4.666	EPSD	COSMIC;CCLE	1.932	Down-regulation
CMGC_CDK_CDK9_CDK9_ST	P06400	RB1	P50750	CDK9	T356	N361Y	361	Missense	distal	5	no	4.712	4.538	EPSD	COSMIC	1.932	Down-regulation
CMGC_CDK_CDK9_CDK9_ST	P06400	RB1	P50750	CDK9	T373	P370S	370	Missense	distal	-3	no	4.052	4.047	EPSD	COSMIC	1.932	Down-regulation
CMGC_CDK_CDK9_CDK9_ST	P06400	RB1	P50750	CDK9	T373	P374L	374	Missense	proximal	1	no	4.052	-1.546	EPSD	COSMIC	1.932	Loss
CMGC_CDK_CDK9_CDK9_ST	P06400	RB1	P50750	CDK9	T373	N367D	367	Missense	distal	-6	no	4.052	3.803	EPSD	COSMIC	1.932	Down-regulation
CMGC_CDK_CDK9_CDK9_ST	P06400	RB1	P50750	CDK9	T373	P370L	370	Missense	distal	-3	no	4.052	4.137	EPSD	COSMIC	1.932	Up-regulation
CMGC_CDK_CDK9_CDK9_ST	P06400	RB1	P50750	CDK9	S567	W563C	563	Missense	distal	-4	no	4.316	4.312	EPSD	COSMIC	1.932	Down-regulation
CMGC_CDK_CDK9_CDK9_ST	P06400	RB1	P50750	CDK9	S567	S560P	560	Missense	distal	-7	no	4.316	4.311	EPSD	COSMIC	1.932	Down-regulation
CMGC_CDK_CDK9_CDK9_ST	P06400	RB1	P50750	CDK9	S567	L564V	564	Missense	distal	-3	no	4.316	4.306	EPSD	COSMIC	1.932	Down-regulation
CMGC_CDK_CDK9_CDK9_ST	P06400	RB1	P50750	CDK9	S567	L572F	572	Missense	distal	5	no	4.316	4.284	EPSD	COSMIC	1.932	Down-regulation
CMGC_CDK_CDK9_CDK9_ST	P06400	RB1	P50750	CDK9	S608	R611S	611	Missense	distal	3	no	4.435	4.639	EPSD	COSMIC	1.932	Up-regulation
CMGC_CDK_CDK9_CDK9_ST	P06400	RB1	P50750	CDK9	S608	S612P	612	Missense	distal	4	no	4.435	4.341	EPSD	COSMIC	1.932	Down-regulation
CMGC_CDK_CDK9_CDK9_ST	P06400	RB1	P50750	CDK9	S608	Y606C	606	Missense	proximal	-2	no	4.435	4.321	EPSD	COSMIC	1.932	Down-regulation
CMGC_CDK_CDK9_CDK9_ST	P06400	RB1	P50750	CDK9	S608	P609S	609	Missense	proximal	1	no	4.435	0.701	EPSD	COSMIC	1.932	Loss
CMGC_CDK_CDK9_CDK9_ST	P06400	RB1	P50750	CDK9	S608	M605T	605	Missense	distal	-3	no	4.435	4.419	EPSD	COSMIC	1.932	Down-regulation
CMGC_CDK_CDK9_CDK9_ST	P06400	RB1	P50750	CDK9	S608	L607V	607	Missense	proximal	-1	no	4.435	4.439	EPSD	COSMIC	1.932	Up-regulation
CMGC_CDK_CDK9_CDK9_ST	P06400	RB1	P50750	CDK9	S608	L607I	607	Missense	proximal	-1	no	4.435	4.440	EPSD	COSMIC	1.932	Up-regulation
CMGC_CDK_CDK9_CDK9_ST	P06400	RB1	P50750	CDK9	S612	R611S	611	Missense	proximal	-1	no	4.420	4.475	EPSD	COSMIC	1.932	Up-regulation
CMGC_CDK_CDK9_CDK9_ST	P06400	RB1	P50750	CDK9	S612	S612P	612	Missense	central	0	yes	4.420	0.000	EPSD	COSMIC	1.932	Loss
CMGC_CDK_CDK9_CDK9_ST	P06400	RB1	P50750	CDK9	S612	Y606C	606	Missense	distal	-6	no	4.420	4.332	EPSD	COSMIC	1.932	Down-regulation
CMGC_CDK_CDK9_CDK9_ST	P06400	RB1	P50750	CDK9	S612	P609S	609	Missense	distal	-3	no	4.420	4.415	EPSD	COSMIC	1.932	Down-regulation
CMGC_CDK_CDK9_CDK9_ST	P06400	RB1	P50750	CDK9	S612	M605T	605	Missense	distal	-7	no	4.420	4.407	EPSD	COSMIC	1.932	Down-regulation
CMGC_CDK_CDK9_CDK9_ST	P06400	RB1	P50750	CDK9	S612	L607V	607	Missense	distal	-5	no	4.420	4.460	EPSD	COSMIC	1.932	Up-regulation
CMGC_CDK_CDK9_CDK9_ST	P06400	RB1	P50750	CDK9	S612	L607I	607	Missense	distal	-5	no	4.420	4.463	EPSD	COSMIC	1.932	Up-regulation
CMGC_CDK_CDK9_CDK9_ST	P06400	RB1	P50750	CDK9	T620	R621P	621	Missense	proximal	1	no	0.952	5.128	EPSD	COSMIC	1.932	Gain
CMGC_CDK_CDK9_CDK9_ST	P06400	RB1	P50750	CDK9	T633	S634P	634	Missense	proximal	1	no	1.592	5.326	EPSD	COSMIC	1.932	Gain
CMGC_CDK_CDK9_CDK9_ST	P06400	RB1	P50750	CDK9	S780	P776R	776	Missense	distal	-4	no	5.296	5.200	EPSD	COSMIC	1.932	Down-regulation
CMGC_CDK_CDK9_CDK9_ST	P06400	RB1	P50750	CDK9	S780	H784Y	784	Missense	distal	4	no	5.296	5.284	EPSD	COSMIC	1.932	Down-regulation
CMGC_CDK_CDK9_CDK9_ST	P06400	RB1	P50750	CDK9	S780	P777S	777	Missense	distal	-3	no	5.296	5.291	EPSD	COSMIC	1.932	Down-regulation
CMGC_CDK_CDK9_CDK9_ST	P06400	RB1	P50750	CDK9	S780	P786S	786	Missense	distal	6	no	5.296	5.327	EPSD	COSMIC	1.932	Up-regulation
CMGC_CDK_CDK9_CDK9_ST	P06400	RB1	P50750	CDK9	S780	S773F	773	Missense	distal	-7	no	5.296	5.358	EPSD	COSMIC	1.932	Up-regulation
CMGC_CDK_CDK9_CDK9_ST	P06400	RB1	P50750	CDK9	S788	S795L	795	Missense	distal	7	no	5.074	5.376	EPSD	COSMIC	1.932	Up-regulation
CMGC_CDK_CDK9_CDK9_ST	P06400	RB1	P50750	CDK9	S788	H784Y	784	Missense	distal	-4	no	5.074	5.064	EPSD	COSMIC	1.932	Down-regulation
CMGC_CDK_CDK9_CDK9_ST	P06400	RB1	P50750	CDK9	S788	S794I	794	Missense	distal	6	no	5.074	4.480	EPSD	COSMIC	1.932	Down-regulation
CMGC_CDK_CDK9_CDK9_ST	P06400	RB1	P50750	CDK9	S788	P786S	786	Missense	proximal	-2	no	5.074	4.836	EPSD	COSMIC	1.932	Down-regulation
CMGC_CDK_CDK9_CDK9_ST	P06400	RB1	P50750	CDK9	S788	P793S	793	Missense	distal	5	no	5.074	5.194	EPSD	COSMIC;CCLE	1.932	Up-regulation
CMGC_CDK_CDK9_CDK9_ST	P06400	RB1	P50750	CDK9	S794	S795L	795	Missense	proximal	1	no	2.098	0.234	EPSD	COSMIC	1.932	Loss
CMGC_CDK_CDK9_CDK9_ST	P06400	RB1	P50750	CDK9	S794	R798Q	798	Missense	distal	4	no	2.098	2.150	EPSD	COSMIC;GDSC;CCLE	1.932	Up-regulation
CMGC_CDK_CDK9_CDK9_ST	P06400	RB1	P50750	CDK9	S794	S794I	794	Missense	central	0	yes	2.098	0.000	EPSD	COSMIC	1.932	Loss
CMGC_CDK_CDK9_CDK9_ST	P06400	RB1	P50750	CDK9	S794	G801A	801	Missense	distal	7	no	2.098	2.126	EPSD	COSMIC	1.932	Up-regulation
CMGC_CDK_CDK9_CDK9_ST	P06400	RB1	P50750	CDK9	S794	P793S	793	Missense	proximal	-1	no	2.098	2.135	EPSD	COSMIC;CCLE	1.932	Up-regulation
CMGC_CDK_CDK9_CDK9_ST	P06400	RB1	P50750	CDK9	S795	S795L	795	Missense	central	0	yes	5.687	0.000	PhosphoSitePlus;EPSD	COSMIC	1.932	Loss
CMGC_CDK_CDK9_CDK9_ST	P06400	RB1	P50750	CDK9	S795	G802R	802	Missense	distal	7	no	5.687	5.645	PhosphoSitePlus;EPSD	COSMIC	1.932	Down-regulation
CMGC_CDK_CDK9_CDK9_ST	P06400	RB1	P50750	CDK9	S795	R798Q	798	Missense	distal	3	no	5.687	5.811	PhosphoSitePlus;EPSD	COSMIC;GDSC;CCLE	1.932	Up-regulation
CMGC_CDK_CDK9_CDK9_ST	P06400	RB1	P50750	CDK9	S795	S794I	794	Missense	proximal	-1	no	5.687	5.618	PhosphoSitePlus;EPSD	COSMIC	1.932	Down-regulation
CMGC_CDK_CDK9_CDK9_ST	P06400	RB1	P50750	CDK9	S795	G801A	801	Missense	distal	6	no	5.687	5.648	PhosphoSitePlus;EPSD	COSMIC	1.932	Down-regulation
CMGC_CDK_CDK9_CDK9_ST	P06400	RB1	P50750	CDK9	S795	P793S	793	Missense	proximal	-2	no	5.687	5.448	PhosphoSitePlus;EPSD	COSMIC;CCLE	1.932	Down-regulation
CMGC_CDK_CDK9_CDK9_ST	P06400	RB1	P50750	CDK9	S807	G802R	802	Missense	distal	-5	no	4.492	4.525	EPSD;PhosphoSitePlus	COSMIC	1.932	Up-regulation
CMGC_CDK_CDK9_CDK9_ST	P06400	RB1	P50750	CDK9	S807	K814T	814	Missense	distal	7	no	4.492	4.474	EPSD;PhosphoSitePlus	COSMIC	1.932	Down-regulation
CMGC_CDK_CDK9_CDK9_ST	P06400	RB1	P50750	CDK9	S807	G801A	801	Missense	distal	-6	no	4.492	4.466	EPSD;PhosphoSitePlus	COSMIC	1.932	Down-regulation
CMGC_CDK_CDK9_CDK9_ST	P06400	RB1	P50750	CDK9	S811	G818S	818	Missense	distal	7	no	5.860	5.590	EPSD;PhosphoSitePlus	COSMIC	1.932	Down-regulation
CMGC_CDK_CDK9_CDK9_ST	P06400	RB1	P50750	CDK9	S811	G818C	818	Missense	distal	7	no	5.860	5.923	EPSD;PhosphoSitePlus	COSMIC	1.932	Up-regulation
CMGC_CDK_CDK9_CDK9_ST	P06400	RB1	P50750	CDK9	S811	K814T	814	Missense	distal	3	no	5.860	5.843	EPSD;PhosphoSitePlus	COSMIC	1.932	Down-regulation
CMGC_CDK_CDK9_CDK9_ST	P06400	RB1	P50750	CDK9	T821	G818S	818	Missense	distal	-3	no	4.624	4.543	EPSD	COSMIC	1.932	Down-regulation
CMGC_CDK_CDK9_CDK9_ST	P06400	RB1	P50750	CDK9	T821	P822S	822	Missense	proximal	1	no	4.624	0.890	EPSD	COSMIC	1.932	Loss
CMGC_CDK_CDK9_CDK9_ST	P06400	RB1	P50750	CDK9	T821	G818C	818	Missense	distal	-3	no	4.624	4.635	EPSD	COSMIC	1.932	Up-regulation
CMGC_CDK_CDK9_CDK9_ST	P06400	RB1	P50750	CDK9	T821	K814T	814	Missense	distal	-7	no	4.624	4.622	EPSD	COSMIC	1.932	Down-regulation
CMGC_CDK_CDK9_CDK9_ST	P06400	RB1	P50750	CDK9	T826	S829L	829	Missense	distal	3	no	4.640	4.329	EPSD	COSMIC	1.932	Down-regulation
CMGC_CDK_CDK9_CDK9_ST	P06400	RB1	P50750	CDK9	T826	P822S	822	Missense	distal	-4	no	4.640	4.660	EPSD	COSMIC	1.932	Up-regulation
CMGC_CDK_CDK9_CDK9_ST	P06400	RB1	P50750	CDK9	S866	L859F	859	Missense	distal	-7	no	2.057	2.058	EPSD	COSMIC	1.932	Up-regulation
CMGC_CDK_CDK9_CDK9_ST	P06400	RB1	P50750	CDK9	S866	K873T	873	Missense	distal	7	no	2.057	2.040	EPSD	COSMIC	1.932	Down-regulation
CMGC_CDK_CDK9_CDK9_ST	P06400	RB1	P50750	CDK9	T905	M904I	904	Missense	proximal	-1	no	2.236	2.225	EPSD	COSMIC	1.932	Down-regulation
CMGC_CDK_CDK9_CDK9_ST	P06400	RB1	P50750	CDK9	T905	R908L	908	Missense	distal	3	no	2.236	2.129	EPSD	COSMIC	1.932	Down-regulation
CMGC_CDK_CDK9_CDK9_ST	P06400	RB1	P50750	CDK9	T922	D918N	918	Missense	distal	-4	no	2.451	2.527	EPSD	COSMIC	1.932	Up-regulation
CMGC_CDK_CDK9_CDK9_ST	P06400	RB1	P50750	CDK9	S923	D918N	918	Missense	distal	-5	no	2.842	3.057	EPSD	COSMIC	1.932	Up-regulation
CMGC_CDK_CDK9_CDK9_ST	P04637	TP53	P50750	CDK9	S15	E11Q	11	Missense	distal	-4	no	1.964	2.026	EPSD	COSMIC;GDSC;CCLE	1.932	Up-regulation
CMGC_CDK_CDK9_CDK9_ST	P04637	TP53	P50750	CDK9	S15	S20L	20	Missense	distal	5	no	1.964	1.520	EPSD	COSMIC	1.932	Loss
CMGC_CDK_CDK9_CDK9_ST	P04637	TP53	P50750	CDK9	S15	Q16L	16	Missense	proximal	1	no	1.964	-0.079	EPSD	COSMIC;GDSC;CCLE	1.932	Loss
CMGC_CDK_CDK9_CDK9_ST	P04637	TP53	P50750	CDK9	S15	P13S	13	Missense	proximal	-2	no	1.964	1.726	EPSD	COSMIC	1.932	Loss
CMGC_CDK_CDK9_CDK9_ST	P04637	TP53	P50750	CDK9	S15	E17K	17	Missense	proximal	2	no	1.964	1.947	EPSD	COSMIC	1.932	Down-regulation
CMGC_CDK_CDK9_CDK9_ST	P04637	TP53	P50750	CDK9	S15	V10I	10	Missense	distal	-5	no	1.964	1.967	EPSD	COSMIC	1.932	Up-regulation
CMGC_CDK_CDK9_CDK9_ST	P04637	TP53	P50750	CDK9	S15	P8L	8	Missense	distal	-7	no	1.964	2.031	EPSD	COSMIC	1.932	Up-regulation
CMGC_CDK_CDK9_CDK9_ST	P04637	TP53	P50750	CDK9	S15	P8S	8	Missense	distal	-7	no	1.964	1.969	EPSD	COSMIC	1.932	Up-regulation
CMGC_CDK_CDK9_CDK9_ST	P04637	TP53	P50750	CDK9	S15	P13L	13	Missense	proximal	-2	no	1.964	1.176	EPSD	COSMIC	1.932	Loss
CMGC_CDK_CDK9_CDK9_ST	P04637	TP53	P50750	CDK9	S15	V10G	10	Missense	distal	-5	no	1.964	2.026	EPSD	COSMIC	1.932	Up-regulation
CMGC_CDK_CDK9_CDK9_ST	P04637	TP53	P50750	CDK9	S15	T18A	18	Missense	distal	3	no	1.964	1.877	EPSD	COSMIC	1.932	Loss
CMGC_CDK_CDK9_CDK9_ST	P04637	TP53	P50750	CDK9	S15	F19S	19	Missense	distal	4	no	1.964	2.117	EPSD	COSMIC	1.932	Up-regulation
CMGC_CDK_CDK9_CDK9_ST	P04637	TP53	P50750	CDK9	S15	E17V	17	Missense	proximal	2	no	1.964	1.995	EPSD	COSMIC	1.932	Up-regulation
CMGC_CDK_CDK9_CDK9_ST	P04637	TP53	P50750	CDK9	S15	S9G	9	Missense	distal	-6	no	1.964	1.595	EPSD	COSMIC	1.932	Loss
CMGC_CDK_CDK9_CDK9_ST	P04637	TP53	P50750	CDK9	S15	T18I	18	Missense	distal	3	no	1.964	1.878	EPSD	COSMIC	1.932	Loss
CMGC_CDK_CDK9_CDK9_ST	P04637	TP53	P50750	CDK9	S15	T18K	18	Missense	distal	3	no	1.964	1.981	EPSD	COSMIC	1.932	Up-regulation
CMGC_CDK_CDK9_CDK9_ST	P04637	TP53	P50750	CDK9	S15	T18R	18	Missense	distal	3	no	1.964	1.940	EPSD	COSMIC	1.932	Down-regulation
CMGC_CDK_CDK9_CDK9_ST	P04637	TP53	P50750	CDK9	S15	S15I	15	Missense	central	0	yes	1.964	0.000	EPSD	COSMIC	1.932	Loss
CMGC_CDK_CDK9_CDK9_ST	P04637	TP53	P50750	CDK9	S33	M40I	40	Missense	distal	7	no	5.662	5.709	EPSD;PhosphoSitePlus	COSMIC	1.932	Up-regulation
CMGC_CDK_CDK9_CDK9_ST	P04637	TP53	P50750	CDK9	S33	V31I	31	Missense	proximal	-2	no	5.662	5.591	EPSD;PhosphoSitePlus	COSMIC;GDSC;CCLE	1.932	Down-regulation
CMGC_CDK_CDK9_CDK9_ST	P04637	TP53	P50750	CDK9	S33	P36L	36	Missense	distal	3	no	5.662	5.316	EPSD;PhosphoSitePlus	COSMIC;GDSC;CCLE	1.932	Down-regulation
CMGC_CDK_CDK9_CDK9_ST	P04637	TP53	P50750	CDK9	S33	L35F	35	Missense	proximal	2	no	5.662	5.663	EPSD;PhosphoSitePlus	COSMIC	1.932	Up-regulation
CMGC_CDK_CDK9_CDK9_ST	P04637	TP53	P50750	CDK9	S33	Q38L	38	Missense	distal	5	no	5.662	5.376	EPSD;PhosphoSitePlus	COSMIC	1.932	Down-regulation
CMGC_CDK_CDK9_CDK9_ST	P04637	TP53	P50750	CDK9	S33	S37T	37	Missense	distal	4	no	5.662	5.570	EPSD;PhosphoSitePlus	COSMIC	1.932	Down-regulation
CMGC_CDK_CDK9_CDK9_ST	P04637	TP53	P50750	CDK9	S33	L26P	26	Missense	distal	-7	no	5.662	5.596	EPSD;PhosphoSitePlus	COSMIC	1.932	Down-regulation
CMGC_CDK_CDK9_CDK9_ST	P04637	TP53	P50750	CDK9	S33	P36S	36	Missense	distal	3	no	5.662	5.627	EPSD;PhosphoSitePlus	COSMIC;GDSC;CCLE	1.932	Down-regulation
CMGC_CDK_CDK9_CDK9_ST	P04637	TP53	P50750	CDK9	S33	A39V	39	Missense	distal	6	no	5.662	5.656	EPSD;PhosphoSitePlus	COSMIC	1.932	Down-regulation
CMGC_CDK_CDK9_CDK9_ST	P04637	TP53	P50750	CDK9	S33	A39S	39	Missense	distal	6	no	5.662	6.211	EPSD;PhosphoSitePlus	COSMIC	1.932	Up-regulation
CMGC_CDK_CDK9_CDK9_ST	P04637	TP53	P50750	CDK9	S33	N30K	30	Missense	distal	-3	no	5.662	5.679	EPSD;PhosphoSitePlus	COSMIC	1.932	Up-regulation
CMGC_CDK_CDK9_CDK9_ST	P04637	TP53	P50750	CDK9	S33	A39T	39	Missense	distal	6	no	5.662	5.847	EPSD;PhosphoSitePlus	COSMIC	1.932	Up-regulation
CMGC_CDK_CDK9_CDK9_ST	P04637	TP53	P50750	CDK9	S33	P27T	27	Missense	distal	-6	no	5.662	5.296	EPSD;PhosphoSitePlus	COSMIC	1.932	Down-regulation
CMGC_CDK_CDK9_CDK9_ST	P04637	TP53	P50750	CDK9	S33	P36R	36	Missense	distal	3	no	5.662	5.423	EPSD;PhosphoSitePlus	COSMIC	1.932	Down-regulation
CMGC_CDK_CDK9_CDK9_ST	P04637	TP53	P50750	CDK9	S33	L35R	35	Missense	proximal	2	no	5.662	5.602	EPSD;PhosphoSitePlus	COSMIC	1.932	Down-regulation
CMGC_CDK_CDK9_CDK9_ST	P04637	TP53	P50750	CDK9	S33	L35H	35	Missense	proximal	2	no	5.662	5.615	EPSD;PhosphoSitePlus	COSMIC	1.932	Down-regulation
CMGC_CDK_CDK9_CDK9_ST	P04637	TP53	P50750	CDK9	S33	L35P	35	Missense	proximal	2	no	5.662	5.497	EPSD;PhosphoSitePlus	COSMIC	1.932	Down-regulation
CMGC_CDK_CDK9_CDK9_ST	P04637	TP53	P50750	CDK9	S33	L35I	35	Missense	proximal	2	no	5.662	5.643	EPSD;PhosphoSitePlus	COSMIC	1.932	Down-regulation
CMGC_CDK_CDK9_CDK9_ST	P04637	TP53	P50750	CDK9	S33	L35V	35	Missense	proximal	2	no	5.662	5.628	EPSD;PhosphoSitePlus	COSMIC	1.932	Down-regulation
CMGC_CDK_CDK9_CDK9_ST	P04637	TP53	P50750	CDK9	S46	M40I	40	Missense	distal	-6	no	4.557	4.494	EPSD	COSMIC	1.932	Down-regulation
CMGC_CDK_CDK9_CDK9_ST	P04637	TP53	P50750	CDK9	S46	W53C	53	Missense	distal	7	no	4.557	4.566	EPSD	COSMIC	1.932	Up-regulation
CMGC_CDK_CDK9_CDK9_ST	P04637	TP53	P50750	CDK9	S46	W53G	53	Missense	distal	7	no	4.557	4.502	EPSD	COSMIC	1.932	Down-regulation
CMGC_CDK_CDK9_CDK9_ST	P04637	TP53	P50750	CDK9	S46	S46F	46	Missense	central	0	yes	4.557	0.000	EPSD	COSMIC	1.932	Loss
CMGC_CDK_CDK9_CDK9_ST	P04637	TP53	P50750	CDK9	S46	D49Y	49	Missense	distal	3	no	4.557	4.598	EPSD	COSMIC	1.932	Up-regulation
CMGC_CDK_CDK9_CDK9_ST	P04637	TP53	P50750	CDK9	S46	P47L	47	Missense	proximal	1	no	4.557	-1.041	EPSD	COSMIC	1.932	Loss
CMGC_CDK_CDK9_CDK9_ST	P04637	TP53	P50750	CDK9	S46	D49H	49	Missense	distal	3	no	4.557	4.623	EPSD	COSMIC;GDSC;CCLE	1.932	Up-regulation
CMGC_CDK_CDK9_CDK9_ST	P04637	TP53	P50750	CDK9	S46	P47S	47	Missense	proximal	1	no	4.557	0.823	EPSD	COSMIC	1.932	Loss
CMGC_CDK_CDK9_CDK9_ST	P04637	TP53	P50750	CDK9	S46	D41N	41	Missense	distal	-5	no	4.557	4.772	EPSD	COSMIC	1.932	Up-regulation
CMGC_CDK_CDK9_CDK9_ST	P04637	TP53	P50750	CDK9	S46	D48H	48	Missense	proximal	2	no	4.557	4.524	EPSD	COSMIC	1.932	Down-regulation
CMGC_CDK_CDK9_CDK9_ST	P04637	TP53	P50750	CDK9	S46	D49N	49	Missense	distal	3	no	4.557	4.708	EPSD	COSMIC	1.932	Up-regulation
CMGC_CDK_CDK9_CDK9_ST	P04637	TP53	P50750	CDK9	S46	M44I	44	Missense	proximal	-2	no	4.557	4.469	EPSD	COSMIC	1.932	Down-regulation
CMGC_CDK_CDK9_CDK9_ST	P04637	TP53	P50750	CDK9	S46	Q52H	52	Missense	distal	6	no	4.557	4.263	EPSD	COSMIC	1.932	Down-regulation
CMGC_CDK_CDK9_CDK9_ST	P04637	TP53	P50750	CDK9	S46	D49V	49	Missense	distal	3	no	4.557	4.583	EPSD	COSMIC	1.932	Up-regulation
CMGC_CDK_CDK9_CDK9_ST	P04637	TP53	P50750	CDK9	S46	A39V	39	Missense	distal	-7	no	4.557	4.552	EPSD	COSMIC	1.932	Down-regulation
CMGC_CDK_CDK9_CDK9_ST	P04637	TP53	P50750	CDK9	S46	A39S	39	Missense	distal	-7	no	4.557	4.500	EPSD	COSMIC	1.932	Down-regulation
CMGC_CDK_CDK9_CDK9_ST	P04637	TP53	P50750	CDK9	S46	D42Y	42	Missense	distal	-4	no	4.557	4.566	EPSD	COSMIC	1.932	Up-regulation
CMGC_CDK_CDK9_CDK9_ST	P04637	TP53	P50750	CDK9	S46	M44R	44	Missense	proximal	-2	no	4.557	4.635	EPSD	COSMIC	1.932	Up-regulation
CMGC_CDK_CDK9_CDK9_ST	P04637	TP53	P50750	CDK9	S46	S46P	46	Missense	central	0	yes	4.557	0.000	EPSD	COSMIC	1.932	Loss
CMGC_CDK_CDK9_CDK9_ST	P04637	TP53	P50750	CDK9	S46	M44V	44	Missense	proximal	-2	no	4.557	4.541	EPSD	COSMIC	1.932	Down-regulation
CMGC_CDK_CDK9_CDK9_ST	P04637	TP53	P50750	CDK9	S46	L45P	45	Missense	proximal	-1	no	4.557	4.595	EPSD	COSMIC	1.932	Up-regulation
CMGC_CDK_CDK9_CDK9_ST	P04637	TP53	P50750	CDK9	S46	M44T	44	Missense	proximal	-2	no	4.557	4.699	EPSD	COSMIC	1.932	Up-regulation
CMGC_CDK_CDK9_CDK9_ST	P04637	TP53	P50750	CDK9	S46	A39T	39	Missense	distal	-7	no	4.557	4.534	EPSD	COSMIC	1.932	Down-regulation
CMGC_CDK_CDK9_CDK9_ST	P04637	TP53	P50750	CDK9	S46	L43F	43	Missense	distal	-3	no	4.557	4.559	EPSD	COSMIC	1.932	Up-regulation
CMGC_CDK_CDK9_CDK9_ST	P04637	TP53	P50750	CDK9	S46	D41H	41	Missense	distal	-5	no	4.557	4.642	EPSD	COSMIC	1.932	Up-regulation
CMGC_CDK_CDK9_CDK9_ST	P04637	TP53	P50750	CDK9	S46	D49E	49	Missense	distal	3	no	4.557	4.611	EPSD	COSMIC	1.932	Up-regulation
CMGC_CDK_CDK9_CDK9_ST	P04637	TP53	P50750	CDK9	S46	D49G	49	Missense	distal	3	no	4.557	4.584	EPSD	COSMIC	1.932	Up-regulation
CMGC_CDK_CDK9_CDK9_ST	P04637	TP53	P50750	CDK9	S46	D48A	48	Missense	proximal	2	no	4.557	4.561	EPSD	COSMIC	1.932	Up-regulation
CMGC_CDK_CDK9_CDK9_ST	P04637	TP53	P50750	CDK9	S46	D48Y	48	Missense	proximal	2	no	4.557	4.561	EPSD	COSMIC	1.932	Up-regulation
CMGC_CDK_CDK9_CDK9_ST	P04637	TP53	P50750	CDK9	S46	D48E	48	Missense	proximal	2	no	4.557	4.506	EPSD	COSMIC	1.932	Down-regulation
CMGC_CDK_CDK9_CDK9_ST	P04637	TP53	P50750	CDK9	S46	D49I	49	Missense	distal	3	no	4.557	4.569	EPSD	COSMIC	1.932	Up-regulation
CMGC_CDK_CDK9_CDK9_ST	P04637	TP53	P50750	CDK9	S46	D41E	41	Missense	distal	-5	no	4.557	4.653	EPSD	COSMIC	1.932	Up-regulation
CMGC_CDK_CDK9_CDK9_ST	P04637	TP53	P50750	CDK9	T81	P77A	77	Missense	distal	-4	no	4.981	4.856	EPSD	COSMIC	1.932	Down-regulation
CMGC_CDK_CDK9_CDK9_ST	P04637	TP53	P50750	CDK9	T81	A76T	76	Missense	distal	-5	no	4.981	5.113	EPSD	COSMIC	1.932	Up-regulation
CMGC_CDK_CDK9_CDK9_ST	P04637	TP53	P50750	CDK9	T81	A83T	83	Missense	proximal	2	no	4.981	4.906	EPSD	COSMIC	1.932	Down-regulation
CMGC_CDK_CDK9_CDK9_ST	P04637	TP53	P50750	CDK9	T81	T81I	81	Missense	central	0	yes	4.981	0.000	EPSD	COSMIC	1.932	Loss
CMGC_CDK_CDK9_CDK9_ST	P04637	TP53	P50750	CDK9	T81	A84V	84	Missense	distal	3	no	4.981	4.995	EPSD	COSMIC	1.932	Up-regulation
CMGC_CDK_CDK9_CDK9_ST	P04637	TP53	P50750	CDK9	T81	P80L	80	Missense	proximal	-1	no	4.981	4.943	EPSD	COSMIC	1.932	Down-regulation
CMGC_CDK_CDK9_CDK9_ST	P04637	TP53	P50750	CDK9	T81	A86V	86	Missense	distal	5	no	4.981	4.953	EPSD	COSMIC	1.932	Down-regulation
CMGC_CDK_CDK9_CDK9_ST	P04637	TP53	P50750	CDK9	T81	P85S	85	Missense	distal	4	no	4.981	5.074	EPSD	COSMIC	1.932	Up-regulation
CMGC_CDK_CDK9_CDK9_ST	P04637	TP53	P50750	CDK9	T81	A79T	79	Missense	proximal	-2	no	4.981	5.189	EPSD	COSMIC	1.932	Up-regulation
CMGC_CDK_CDK9_CDK9_ST	P04637	TP53	P50750	CDK9	T81	A84G	84	Missense	distal	3	no	4.981	4.996	EPSD	COSMIC	1.932	Up-regulation
CMGC_CDK_CDK9_CDK9_ST	P04637	TP53	P50750	CDK9	T81	A78V	78	Missense	distal	-3	no	4.981	4.972	EPSD	COSMIC	1.932	Down-regulation
CMGC_CDK_CDK9_CDK9_ST	P04637	TP53	P50750	CDK9	T81	A78S	78	Missense	distal	-3	no	4.981	4.892	EPSD	COSMIC	1.932	Down-regulation
CMGC_CDK_CDK9_CDK9_ST	P04637	TP53	P50750	CDK9	T81	P87L	87	Missense	distal	6	no	4.981	4.375	EPSD	COSMIC	1.932	Down-regulation
CMGC_CDK_CDK9_CDK9_ST	P04637	TP53	P50750	CDK9	T81	P85L	85	Missense	distal	4	no	4.981	4.939	EPSD	COSMIC	1.932	Down-regulation
CMGC_CDK_CDK9_CDK9_ST	P04637	TP53	P50750	CDK9	T81	P82S	82	Missense	proximal	1	no	4.981	1.247	EPSD	COSMIC	1.932	Loss
CMGC_CDK_CDK9_CDK9_ST	P04637	TP53	P50750	CDK9	T81	P77S	77	Missense	distal	-4	no	4.981	5.001	EPSD	COSMIC	1.932	Up-regulation
CMGC_CDK_CDK9_CDK9_ST	P04637	TP53	P50750	CDK9	T81	P80S	80	Missense	proximal	-1	no	4.981	5.017	EPSD	COSMIC	1.932	Up-regulation
CMGC_CDK_CDK9_CDK9_ST	P04637	TP53	P50750	CDK9	T81	A84T	84	Missense	distal	3	no	4.981	5.068	EPSD	COSMIC	1.932	Up-regulation
CMGC_CDK_CDK9_CDK9_ST	P04637	TP53	P50750	CDK9	T81	A83E	83	Missense	proximal	2	no	4.981	4.926	EPSD	COSMIC	1.932	Down-regulation
CMGC_CDK_CDK9_CDK9_ST	P04637	TP53	P50750	CDK9	T81	P85T	85	Missense	distal	4	no	4.981	4.982	EPSD	COSMIC	1.932	Up-regulation
CMGC_CDK_CDK9_CDK9_ST	P04637	TP53	P50750	CDK9	T81	A74V	74	Missense	distal	-7	no	4.981	4.976	EPSD	COSMIC	1.932	Down-regulation
CMGC_CDK_CDK9_CDK9_ST	P04637	TP53	P50750	CDK9	T81	P75S	75	Missense	distal	-6	no	4.981	4.849	EPSD	COSMIC	1.932	Down-regulation
CMGC_CDK_CDK9_CDK9_ST	P04637	TP53	P50750	CDK9	T81	A76V	76	Missense	distal	-5	no	4.981	4.973	EPSD	COSMIC	1.932	Down-regulation
CMGC_CDK_CDK9_CDK9_ST	P04637	TP53	P50750	CDK9	T81	P75R	75	Missense	distal	-6	no	4.981	4.561	EPSD	COSMIC	1.932	Down-regulation
CMGC_CDK_CDK9_CDK9_ST	P04637	TP53	P50750	CDK9	T81	P87H	87	Missense	distal	6	no	4.981	4.504	EPSD	COSMIC	1.932	Down-regulation
CMGC_CDK_CDK9_CDK9_ST	P04637	TP53	P50750	CDK9	T81	P87T	87	Missense	distal	6	no	4.981	4.648	EPSD	COSMIC	1.932	Down-regulation
CMGC_CDK_CDK9_CDK9_ST	P04637	TP53	P50750	CDK9	T81	P87S	87	Missense	distal	6	no	4.981	5.012	EPSD	COSMIC	1.932	Up-regulation
CMGC_CDK_CDK9_CDK9_ST	P04637	TP53	P50750	CDK9	T81	P87R	87	Missense	distal	6	no	4.981	4.554	EPSD	COSMIC	1.932	Down-regulation
CMGC_CDK_CDK9_CDK9_ST	P04637	TP53	P50750	CDK9	T81	P87C	87	Missense	distal	6	no	4.981	4.341	EPSD	COSMIC	1.932	Down-regulation
CMGC_CDK_CDK9_CDK9_ST	P04637	TP53	P50750	CDK9	T81	A86E	86	Missense	distal	5	no	4.981	5.024	EPSD	COSMIC	1.932	Up-regulation
CMGC_CDK_CDK9_CDK9_ST	P04637	TP53	P50750	CDK9	T81	A86S	86	Missense	distal	5	no	4.981	5.379	EPSD	COSMIC	1.932	Up-regulation
CMGC_CDK_CDK9_CDK9_ST	P04637	TP53	P50750	CDK9	T81	A83V	83	Missense	proximal	2	no	4.981	4.956	EPSD	COSMIC	1.932	Down-regulation
CMGC_CDK_CDK9_CDK9_ST	P04637	TP53	P50750	CDK9	S127	C124W	124	Missense	distal	-3	no	4.849	4.848	EPSD	COSMIC	1.932	Down-regulation
CMGC_CDK_CDK9_CDK9_ST	P04637	TP53	P50750	CDK9	S127	C124S	124	Missense	distal	-3	no	4.849	4.757	EPSD	COSMIC	1.932	Down-regulation
CMGC_CDK_CDK9_CDK9_ST	P04637	TP53	P50750	CDK9	S127	S127A	127	Missense	central	0	yes	4.849	0.000	EPSD	COSMIC	1.932	Loss
CMGC_CDK_CDK9_CDK9_ST	P04637	TP53	P50750	CDK9	S127	S127L	127	Missense	central	0	yes	4.849	0.000	EPSD	COSMIC	1.932	Loss
CMGC_CDK_CDK9_CDK9_ST	P04637	TP53	P50750	CDK9	S127	C124T	124	Missense	distal	-3	no	4.849	4.812	EPSD	COSMIC	1.932	Down-regulation
CMGC_CDK_CDK9_CDK9_ST	P04637	TP53	P50750	CDK9	S127	S127I	127	Missense	central	0	yes	4.849	0.000	EPSD	COSMIC	1.932	Loss
CMGC_CDK_CDK9_CDK9_ST	P04637	TP53	P50750	CDK9	S127	S127G	127	Missense	central	0	yes	4.849	0.000	EPSD	COSMIC	1.932	Loss
CMGC_CDK_CDK9_CDK9_ST	P04637	TP53	P50750	CDK9	S127	N131H	131	Missense	distal	4	no	4.849	4.809	EPSD	COSMIC	1.932	Down-regulation
CMGC_CDK_CDK9_CDK9_ST	P04637	TP53	P50750	CDK9	S127	N131D	131	Missense	distal	4	no	4.849	4.787	EPSD	COSMIC	1.932	Down-regulation
CMGC_CDK_CDK9_CDK9_ST	P04637	TP53	P50750	CDK9	S127	T125I	125	Missense	proximal	-2	no	4.849	4.619	EPSD	COSMIC	1.932	Down-regulation
CMGC_CDK_CDK9_CDK9_ST	P04637	TP53	P50750	CDK9	S127	F134I	134	Missense	distal	7	no	4.849	4.809	EPSD	COSMIC	1.932	Down-regulation
CMGC_CDK_CDK9_CDK9_ST	P04637	TP53	P50750	CDK9	S127	K120T	120	Missense	distal	-7	no	4.849	4.847	EPSD	COSMIC	1.932	Down-regulation
CMGC_CDK_CDK9_CDK9_ST	P04637	TP53	P50750	CDK9	S127	F134S	134	Missense	distal	7	no	4.849	4.521	EPSD	COSMIC	1.932	Down-regulation
CMGC_CDK_CDK9_CDK9_ST	P04637	TP53	P50750	CDK9	S127	T125K	125	Missense	proximal	-2	no	4.849	4.841	EPSD	COSMIC	1.932	Down-regulation
CMGC_CDK_CDK9_CDK9_ST	P04637	TP53	P50750	CDK9	S127	M133I	133	Missense	distal	6	no	4.849	4.764	EPSD	COSMIC	1.932	Down-regulation
CMGC_CDK_CDK9_CDK9_ST	P04637	TP53	P50750	CDK9	S127	N131K	131	Missense	distal	4	no	4.849	4.827	EPSD	COSMIC;CCLE	1.932	Down-regulation
CMGC_CDK_CDK9_CDK9_ST	P04637	TP53	P50750	CDK9	S127	P128S	128	Missense	proximal	1	no	4.849	1.115	EPSD	COSMIC	1.932	Loss
CMGC_CDK_CDK9_CDK9_ST	P04637	TP53	P50750	CDK9	S127	M133L	133	Missense	distal	6	no	4.849	4.722	EPSD	COSMIC	1.932	Down-regulation
CMGC_CDK_CDK9_CDK9_ST	P04637	TP53	P50750	CDK9	S127	A129T	129	Missense	proximal	2	no	4.849	4.775	EPSD	COSMIC	1.932	Down-regulation
CMGC_CDK_CDK9_CDK9_ST	P04637	TP53	P50750	CDK9	S127	T123I	123	Missense	distal	-4	no	4.849	4.802	EPSD	COSMIC	1.932	Down-regulation
CMGC_CDK_CDK9_CDK9_ST	P04637	TP53	P50750	CDK9	S127	A129G	129	Missense	proximal	2	no	4.849	4.836	EPSD	COSMIC	1.932	Down-regulation
CMGC_CDK_CDK9_CDK9_ST	P04637	TP53	P50750	CDK9	S127	K132W	132	Missense	distal	5	no	4.849	4.688	EPSD	COSMIC	1.932	Down-regulation
CMGC_CDK_CDK9_CDK9_ST	P04637	TP53	P50750	CDK9	S127	A129V	129	Missense	proximal	2	no	4.849	4.825	EPSD	COSMIC	1.932	Down-regulation
CMGC_CDK_CDK9_CDK9_ST	P04637	TP53	P50750	CDK9	S127	P128A	128	Missense	proximal	1	no	4.849	-0.315	EPSD	COSMIC	1.932	Loss
CMGC_CDK_CDK9_CDK9_ST	P04637	TP53	P50750	CDK9	S127	L130I	130	Missense	distal	3	no	4.849	4.893	EPSD	COSMIC	1.932	Up-regulation
CMGC_CDK_CDK9_CDK9_ST	P04637	TP53	P50750	CDK9	S127	S121F	121	Missense	distal	-6	no	4.849	4.411	EPSD	COSMIC	1.932	Down-regulation
CMGC_CDK_CDK9_CDK9_ST	P04637	TP53	P50750	CDK9	S127	A129D	129	Missense	proximal	2	no	4.849	4.846	EPSD	COSMIC	1.932	Down-regulation
CMGC_CDK_CDK9_CDK9_ST	P04637	TP53	P50750	CDK9	S127	K120Q	120	Missense	distal	-7	no	4.849	4.836	EPSD	COSMIC	1.932	Down-regulation
CMGC_CDK_CDK9_CDK9_ST	P04637	TP53	P50750	CDK9	S127	T125S	125	Missense	proximal	-2	no	4.849	5.103	EPSD	COSMIC	1.932	Up-regulation
CMGC_CDK_CDK9_CDK9_ST	P04637	TP53	P50750	CDK9	S127	P128L	128	Missense	proximal	1	no	4.849	-0.749	EPSD	COSMIC	1.932	Loss
CMGC_CDK_CDK9_CDK9_ST	P04637	TP53	P50750	CDK9	S127	V122L	122	Missense	distal	-5	no	4.849	4.810	EPSD	COSMIC	1.932	Down-regulation
CMGC_CDK_CDK9_CDK9_ST	P04637	TP53	P50750	CDK9	S127	C124L	124	Missense	distal	-3	no	4.849	4.847	EPSD	COSMIC	1.932	Down-regulation
CMGC_CDK_CDK9_CDK9_ST	P04637	TP53	P50750	CDK9	S127	N131T	131	Missense	distal	4	no	4.849	4.841	EPSD	COSMIC	1.932	Down-regulation
CMGC_CDK_CDK9_CDK9_ST	P04637	TP53	P50750	CDK9	S127	M133V	133	Missense	distal	6	no	4.849	4.804	EPSD	COSMIC	1.932	Down-regulation
CMGC_CDK_CDK9_CDK9_ST	P04637	TP53	P50750	CDK9	T150	P151N	151	Missense	proximal	1	no	5.274	2.220	EPSD	COSMIC	1.932	Down-regulation
CMGC_CDK_CDK9_CDK9_ST	P04637	TP53	P50750	CDK9	T150	P152A	152	Missense	proximal	2	no	5.274	5.429	EPSD	COSMIC	1.932	Up-regulation
CMGC_CDK_CDK9_CDK9_ST	P04637	TP53	P50750	CDK9	T150	P152T	152	Missense	proximal	2	no	5.274	5.354	EPSD	COSMIC	1.932	Up-regulation
CMGC_CDK_CDK9_CDK9_ST	P04637	TP53	P50750	CDK9	T150	P152H	152	Missense	proximal	2	no	5.274	5.392	EPSD	COSMIC	1.932	Up-regulation
CMGC_CDK_CDK9_CDK9_ST	P04637	TP53	P50750	CDK9	T150	P153T	153	Missense	distal	3	no	5.274	5.059	EPSD	COSMIC	1.932	Down-regulation
CMGC_CDK_CDK9_CDK9_ST	P04637	TP53	P50750	CDK9	T150	V147I	147	Missense	distal	-3	no	5.274	5.276	EPSD	COSMIC	1.932	Up-regulation
CMGC_CDK_CDK9_CDK9_ST	P04637	TP53	P50750	CDK9	T150	P153L	153	Missense	distal	3	no	5.274	4.928	EPSD	COSMIC	1.932	Down-regulation
CMGC_CDK_CDK9_CDK9_ST	P04637	TP53	P50750	CDK9	T150	V147D	147	Missense	distal	-3	no	5.274	5.277	EPSD	COSMIC;GDSC;CCLE	1.932	Up-regulation
CMGC_CDK_CDK9_CDK9_ST	P04637	TP53	P50750	CDK9	T150	S149P	149	Missense	proximal	-1	no	5.274	5.237	EPSD	COSMIC	1.932	Down-regulation
CMGC_CDK_CDK9_CDK9_ST	P04637	TP53	P50750	CDK9	T150	P152K	152	Missense	proximal	2	no	5.274	5.357	EPSD	COSMIC	1.932	Up-regulation
CMGC_CDK_CDK9_CDK9_ST	P04637	TP53	P50750	CDK9	T150	P153S	153	Missense	distal	3	no	5.274	5.239	EPSD	COSMIC	1.932	Down-regulation
CMGC_CDK_CDK9_CDK9_ST	P04637	TP53	P50750	CDK9	T150	G154C	154	Missense	distal	4	no	5.274	5.217	EPSD	COSMIC	1.932	Down-regulation
CMGC_CDK_CDK9_CDK9_ST	P04637	TP53	P50750	CDK9	T150	S149F	149	Missense	proximal	-1	no	5.274	5.195	EPSD	COSMIC	1.932	Down-regulation
CMGC_CDK_CDK9_CDK9_ST	P04637	TP53	P50750	CDK9	T150	G154D	154	Missense	distal	4	no	5.274	5.227	EPSD	COSMIC	1.932	Down-regulation
CMGC_CDK_CDK9_CDK9_ST	P04637	TP53	P50750	CDK9	T150	V157I	157	Missense	distal	7	no	5.274	5.279	EPSD	COSMIC	1.932	Up-regulation
CMGC_CDK_CDK9_CDK9_ST	P04637	TP53	P50750	CDK9	T150	W146R	146	Missense	distal	-4	no	5.274	5.320	EPSD	COSMIC	1.932	Up-regulation
CMGC_CDK_CDK9_CDK9_ST	P04637	TP53	P50750	CDK9	T150	Q144R	144	Missense	distal	-6	no	5.274	5.106	EPSD	COSMIC	1.932	Down-regulation
CMGC_CDK_CDK9_CDK9_ST	P04637	TP53	P50750	CDK9	T150	D148V	148	Missense	proximal	-2	no	5.274	5.320	EPSD	COSMIC	1.932	Up-regulation
CMGC_CDK_CDK9_CDK9_ST	P04637	TP53	P50750	CDK9	T150	S149Y	149	Missense	proximal	-1	no	5.274	5.199	EPSD	COSMIC	1.932	Down-regulation
CMGC_CDK_CDK9_CDK9_ST	P04637	TP53	P50750	CDK9	T150	T150I	150	Missense	central	0	yes	5.274	0.000	EPSD	COSMIC	1.932	Loss
CMGC_CDK_CDK9_CDK9_ST	P04637	TP53	P50750	CDK9	T150	S149T	149	Missense	proximal	-1	no	5.274	5.225	EPSD	COSMIC	1.932	Down-regulation
CMGC_CDK_CDK9_CDK9_ST	P04637	TP53	P50750	CDK9	T150	W146G	146	Missense	distal	-4	no	5.274	5.318	EPSD	COSMIC	1.932	Up-regulation
CMGC_CDK_CDK9_CDK9_ST	P04637	TP53	P50750	CDK9	T150	L145M	145	Missense	distal	-5	no	5.274	5.383	EPSD	COSMIC	1.932	Up-regulation
CMGC_CDK_CDK9_CDK9_ST	P04637	TP53	P50750	CDK9	T150	V143L	143	Missense	distal	-7	no	5.274	5.283	EPSD	COSMIC	1.932	Up-regulation
CMGC_CDK_CDK9_CDK9_ST	P04637	TP53	P50750	CDK9	T150	R156S	156	Missense	distal	6	no	5.274	5.732	EPSD	COSMIC	1.932	Up-regulation
CMGC_CDK_CDK9_CDK9_ST	P04637	TP53	P50750	CDK9	T150	D148E	148	Missense	proximal	-2	no	5.274	5.401	EPSD	COSMIC	1.932	Up-regulation
CMGC_CDK_CDK9_CDK9_ST	P04637	TP53	P50750	CDK9	T150	V147F	147	Missense	distal	-3	no	5.274	5.285	EPSD	COSMIC	1.932	Up-regulation
CMGC_CDK_CDK9_CDK9_ST	P04637	TP53	P50750	CDK9	T150	T155A	155	Missense	distal	5	no	5.274	5.155	EPSD	COSMIC	1.932	Down-regulation
CMGC_CDK_CDK9_CDK9_ST	P04637	TP53	P50750	CDK9	T150	V147E	147	Missense	distal	-3	no	5.274	5.257	EPSD	COSMIC	1.932	Down-regulation
CMGC_CDK_CDK9_CDK9_ST	P04637	TP53	P50750	CDK9	T150	G154I	154	Missense	distal	4	no	5.274	5.241	EPSD	COSMIC	1.932	Down-regulation
CMGC_CDK_CDK9_CDK9_ST	P04637	TP53	P50750	CDK9	T150	D148G	148	Missense	proximal	-2	no	5.274	5.301	EPSD	COSMIC	1.932	Up-regulation
CMGC_CDK_CDK9_CDK9_ST	P04637	TP53	P50750	CDK9	T150	Q144K	144	Missense	distal	-6	no	5.274	5.161	EPSD	COSMIC	1.932	Down-regulation
CMGC_CDK_CDK9_CDK9_ST	P04637	TP53	P50750	CDK9	T150	V147A	147	Missense	distal	-3	no	5.274	5.282	EPSD	COSMIC	1.932	Up-regulation
CMGC_CDK_CDK9_CDK9_ST	P04637	TP53	P50750	CDK9	T150	L145V	145	Missense	distal	-5	no	5.274	5.314	EPSD	COSMIC	1.932	Up-regulation
CMGC_CDK_CDK9_CDK9_ST	P04637	TP53	P50750	CDK9	T150	T150K	150	Missense	central	0	yes	5.274	0.000	EPSD	COSMIC	1.932	Loss
CMGC_CDK_CDK9_CDK9_ST	P04637	TP53	P50750	CDK9	T150	P153H	153	Missense	distal	3	no	5.274	5.026	EPSD	COSMIC	1.932	Down-regulation
CMGC_CDK_CDK9_CDK9_ST	P04637	TP53	P50750	CDK9	T150	V157E	157	Missense	distal	7	no	5.274	5.220	EPSD	COSMIC	1.932	Down-regulation
CMGC_CDK_CDK9_CDK9_ST	P04637	TP53	P50750	CDK9	T150	T155S	155	Missense	distal	5	no	5.274	5.553	EPSD	COSMIC;CCLE	1.932	Up-regulation
CMGC_CDK_CDK9_CDK9_ST	P04637	TP53	P50750	CDK9	T150	D148H	148	Missense	proximal	-2	no	5.274	5.343	EPSD	COSMIC	1.932	Up-regulation
CMGC_CDK_CDK9_CDK9_ST	P04637	TP53	P50750	CDK9	T150	P153A	153	Missense	distal	3	no	5.274	4.972	EPSD	COSMIC	1.932	Down-regulation
CMGC_CDK_CDK9_CDK9_ST	P04637	TP53	P50750	CDK9	T150	T150R	150	Missense	central	0	yes	5.274	0.000	EPSD	COSMIC	1.932	Loss
CMGC_CDK_CDK9_CDK9_ST	P04637	TP53	P50750	CDK9	T150	T155L	155	Missense	distal	5	no	5.274	5.108	EPSD	COSMIC	1.932	Down-regulation
CMGC_CDK_CDK9_CDK9_ST	P04637	TP53	P50750	CDK9	T150	G154A	154	Missense	distal	4	no	5.274	5.246	EPSD	COSMIC	1.932	Down-regulation
CMGC_CDK_CDK9_CDK9_ST	P04637	TP53	P50750	CDK9	T150	T150A	150	Missense	central	0	yes	5.274	0.000	EPSD	COSMIC	1.932	Loss
CMGC_CDK_CDK9_CDK9_ST	P04637	TP53	P50750	CDK9	T150	W146C	146	Missense	distal	-4	no	5.274	5.270	EPSD	COSMIC	1.932	Down-regulation
CMGC_CDK_CDK9_CDK9_ST	P04637	TP53	P50750	CDK9	T150	P153F	153	Missense	distal	3	no	5.274	4.936	EPSD	COSMIC	1.932	Down-regulation
CMGC_CDK_CDK9_CDK9_ST	P04637	TP53	P50750	CDK9	T150	D148Y	148	Missense	proximal	-2	no	5.274	5.321	EPSD	COSMIC	1.932	Up-regulation
CMGC_CDK_CDK9_CDK9_ST	P04637	TP53	P50750	CDK9	T150	G154R	154	Missense	distal	4	no	5.274	5.258	EPSD	COSMIC	1.932	Down-regulation
CMGC_CDK_CDK9_CDK9_ST	P04637	TP53	P50750	CDK9	T155	R156S	156	Missense	proximal	1	no	1.591	2.033	EPSD	COSMIC	1.932	Gain
CMGC_CDK_CDK9_CDK9_ST	P04637	TP53	P50750	CDK9	T312	K305T	305	Missense	distal	-7	no	2.262	2.259	EPSD	COSMIC	1.932	Down-regulation
CMGC_CDK_CDK9_CDK9_ST	P04637	TP53	P50750	CDK9	T312	N310T	310	Missense	proximal	-2	no	2.262	2.135	EPSD	COSMIC	1.932	Down-regulation
CMGC_CDK_CDK9_CDK9_ST	P04637	TP53	P50750	CDK9	T312	Q317R	317	Missense	distal	5	no	2.262	2.085	EPSD	COSMIC	1.932	Down-regulation
CMGC_CDK_CDK9_CDK9_ST	P04637	TP53	P50750	CDK9	T312	P309S	309	Missense	distal	-3	no	2.262	2.257	EPSD	COSMIC;GDSC;CCLE	1.932	Down-regulation
CMGC_CDK_CDK9_CDK9_ST	P04637	TP53	P50750	CDK9	T312	K319E	319	Missense	distal	7	no	2.262	2.280	EPSD	COSMIC	1.932	Up-regulation
CMGC_CDK_CDK9_CDK9_ST	P04637	TP53	P50750	CDK9	T312	N310L	310	Missense	proximal	-2	no	2.262	1.838	EPSD	COSMIC	1.932	Loss
CMGC_CDK_CDK9_CDK9_ST	P04637	TP53	P50750	CDK9	T312	K305N	305	Missense	distal	-7	no	2.262	2.250	EPSD	COSMIC	1.932	Down-regulation
CMGC_CDK_CDK9_CDK9_ST	P04637	TP53	P50750	CDK9	T312	N311Y	311	Missense	proximal	-1	no	2.262	2.233	EPSD	COSMIC	1.932	Down-regulation
CMGC_CDK_CDK9_CDK9_ST	P04637	TP53	P50750	CDK9	T312	R306P	306	Missense	distal	-6	no	2.262	2.681	EPSD	COSMIC	1.932	Up-regulation
CMGC_CDK_CDK9_CDK9_ST	P04637	TP53	P50750	CDK9	T312	A307T	307	Missense	distal	-5	no	2.262	2.394	EPSD	COSMIC	1.932	Up-regulation
CMGC_CDK_CDK9_CDK9_ST	P04637	TP53	P50750	CDK9	T312	N311K	311	Missense	proximal	-1	no	2.262	2.259	EPSD	COSMIC	1.932	Down-regulation
CMGC_CDK_CDK9_CDK9_ST	P04637	TP53	P50750	CDK9	T312	Q317K	317	Missense	distal	5	no	2.262	2.119	EPSD	COSMIC	1.932	Down-regulation
CMGC_CDK_CDK9_CDK9_ST	P04637	TP53	P50750	CDK9	T312	K305E	305	Missense	distal	-7	no	2.262	2.266	EPSD	COSMIC	1.932	Up-regulation
CMGC_CDK_CDK9_CDK9_ST	P04637	TP53	P50750	CDK9	T312	S315P	315	Missense	distal	3	no	2.262	2.297	EPSD	COSMIC	1.932	Up-regulation
CMGC_CDK_CDK9_CDK9_ST	P04637	TP53	P50750	CDK9	T312	N310H	310	Missense	proximal	-2	no	2.262	1.999	EPSD	COSMIC	1.932	Down-regulation
CMGC_CDK_CDK9_CDK9_ST	P04637	TP53	P50750	CDK9	T312	R306Q	306	Missense	distal	-6	no	2.262	2.429	EPSD	COSMIC	1.932	Up-regulation
CMGC_CDK_CDK9_CDK9_ST	P04637	TP53	P50750	CDK9	T312	K305R	305	Missense	distal	-7	no	2.262	2.266	EPSD	COSMIC	1.932	Up-regulation
CMGC_CDK_CDK9_CDK9_ST	P04637	TP53	P50750	CDK9	T312	S314C	314	Missense	proximal	2	no	2.262	2.469	EPSD	COSMIC	1.932	Up-regulation
CMGC_CDK_CDK9_CDK9_ST	P04637	TP53	P50750	CDK9	T312	P318A	318	Missense	distal	6	no	2.262	1.744	EPSD	COSMIC	1.932	Loss
CMGC_CDK_CDK9_CDK9_ST	P04637	TP53	P50750	CDK9	T312	P316L	316	Missense	distal	4	no	2.262	2.220	EPSD	COSMIC	1.932	Down-regulation
CMGC_CDK_CDK9_CDK9_ST	P04637	TP53	P50750	CDK9	T312	L308M	308	Missense	distal	-4	no	2.262	2.298	EPSD	COSMIC	1.932	Up-regulation
CMGC_CDK_CDK9_CDK9_ST	P04637	TP53	P50750	CDK9	T312	S313C	313	Missense	proximal	1	no	2.262	0.953	EPSD	COSMIC	1.932	Loss
CMGC_CDK_CDK9_CDK9_ST	P04637	TP53	P50750	CDK9	T312	N311H	311	Missense	proximal	-1	no	2.262	2.248	EPSD	COSMIC	1.932	Down-regulation
CMGC_CDK_CDK9_CDK9_ST	P04637	TP53	P50750	CDK9	T312	L308V	308	Missense	distal	-4	no	2.262	2.271	EPSD	COSMIC	1.932	Up-regulation
CMGC_CDK_CDK9_CDK9_ST	P04637	TP53	P50750	CDK9	T312	S314F	314	Missense	proximal	2	no	2.262	2.465	EPSD	COSMIC	1.932	Up-regulation
CMGC_CDK_CDK9_CDK9_ST	P04637	TP53	P50750	CDK9	T312	K319R	319	Missense	distal	7	no	2.262	2.279	EPSD	COSMIC	1.932	Up-regulation
CMGC_CDK_CDK9_CDK9_ST	P04637	TP53	P50750	CDK9	T312	T312A	312	Missense	central	0	yes	2.262	0.000	EPSD	COSMIC	1.932	Loss
CMGC_CDK_CDK9_CDK9_ST	P04637	TP53	P50750	CDK9	T312	N310D	310	Missense	proximal	-2	no	2.262	1.930	EPSD	COSMIC	1.932	Loss
CMGC_CDK_CDK9_CDK9_ST	P04637	TP53	P50750	CDK9	T312	N311D	311	Missense	proximal	-1	no	2.262	2.233	EPSD	COSMIC	1.932	Down-regulation
CMGC_CDK_CDK9_CDK9_ST	P04637	TP53	P50750	CDK9	T312	P309R	309	Missense	distal	-3	no	2.262	2.323	EPSD	COSMIC	1.932	Up-regulation
CMGC_CDK_CDK9_CDK9_ST	P04637	TP53	P50750	CDK9	T312	S313N	313	Missense	proximal	1	no	2.262	2.942	EPSD	COSMIC	1.932	Up-regulation
CMGC_CDK_CDK9_CDK9_ST	P04637	TP53	P50750	CDK9	T312	Q317P	317	Missense	distal	5	no	2.262	2.300	EPSD	COSMIC	1.932	Up-regulation
CMGC_CDK_CDK9_CDK9_ST	P04637	TP53	P50750	CDK9	T312	A307S	307	Missense	distal	-5	no	2.262	2.679	EPSD	COSMIC	1.932	Up-regulation
CMGC_CDK_CDK9_CDK9_ST	P04637	TP53	P50750	CDK9	T312	P316S	316	Missense	distal	4	no	2.262	2.355	EPSD	COSMIC	1.932	Up-regulation
CMGC_CDK_CDK9_CDK9_ST	P04637	TP53	P50750	CDK9	S313	N310T	310	Missense	distal	-3	no	2.130	2.144	EPSD	COSMIC	1.932	Up-regulation
CMGC_CDK_CDK9_CDK9_ST	P04637	TP53	P50750	CDK9	S313	Q317R	317	Missense	distal	4	no	2.130	2.078	EPSD	COSMIC	1.932	Down-regulation
CMGC_CDK_CDK9_CDK9_ST	P04637	TP53	P50750	CDK9	S313	P309S	309	Missense	distal	-4	no	2.130	2.150	EPSD	COSMIC;GDSC;CCLE	1.932	Up-regulation
CMGC_CDK_CDK9_CDK9_ST	P04637	TP53	P50750	CDK9	S313	K319E	319	Missense	distal	6	no	2.130	2.074	EPSD	COSMIC	1.932	Down-regulation
CMGC_CDK_CDK9_CDK9_ST	P04637	TP53	P50750	CDK9	S313	K320N	320	Missense	distal	7	no	2.130	2.059	EPSD	COSMIC;GDSC;CCLE	1.932	Down-regulation
CMGC_CDK_CDK9_CDK9_ST	P04637	TP53	P50750	CDK9	S313	N310L	310	Missense	distal	-3	no	2.130	2.179	EPSD	COSMIC	1.932	Up-regulation
CMGC_CDK_CDK9_CDK9_ST	P04637	TP53	P50750	CDK9	S313	T312S	312	Missense	proximal	-1	no	2.130	2.179	EPSD	COSMIC	1.932	Up-regulation
CMGC_CDK_CDK9_CDK9_ST	P04637	TP53	P50750	CDK9	S313	N311Y	311	Missense	proximal	-2	no	2.130	1.845	EPSD	COSMIC	1.932	Loss
CMGC_CDK_CDK9_CDK9_ST	P04637	TP53	P50750	CDK9	S313	R306P	306	Missense	distal	-7	no	2.130	2.085	EPSD	COSMIC	1.932	Down-regulation
CMGC_CDK_CDK9_CDK9_ST	P04637	TP53	P50750	CDK9	S313	A307T	307	Missense	distal	-6	no	2.130	2.292	EPSD	COSMIC	1.932	Up-regulation
CMGC_CDK_CDK9_CDK9_ST	P04637	TP53	P50750	CDK9	S313	N311K	311	Missense	proximal	-2	no	2.130	1.994	EPSD	COSMIC	1.932	Down-regulation
CMGC_CDK_CDK9_CDK9_ST	P04637	TP53	P50750	CDK9	S313	Q317K	317	Missense	distal	4	no	2.130	2.087	EPSD	COSMIC	1.932	Down-regulation
CMGC_CDK_CDK9_CDK9_ST	P04637	TP53	P50750	CDK9	S313	S315P	315	Missense	proximal	2	no	2.130	2.168	EPSD	COSMIC	1.932	Up-regulation
CMGC_CDK_CDK9_CDK9_ST	P04637	TP53	P50750	CDK9	S313	N310H	310	Missense	distal	-3	no	2.130	2.160	EPSD	COSMIC	1.932	Up-regulation
CMGC_CDK_CDK9_CDK9_ST	P04637	TP53	P50750	CDK9	S313	R306Q	306	Missense	distal	-7	no	2.130	2.113	EPSD	COSMIC	1.932	Down-regulation
CMGC_CDK_CDK9_CDK9_ST	P04637	TP53	P50750	CDK9	S313	S314C	314	Missense	proximal	1	no	2.130	0.822	EPSD	COSMIC	1.932	Loss
CMGC_CDK_CDK9_CDK9_ST	P04637	TP53	P50750	CDK9	S313	P318A	318	Missense	distal	5	no	2.130	1.852	EPSD	COSMIC	1.932	Loss
CMGC_CDK_CDK9_CDK9_ST	P04637	TP53	P50750	CDK9	S313	P316L	316	Missense	distal	3	no	2.130	1.785	EPSD	COSMIC	1.932	Loss
CMGC_CDK_CDK9_CDK9_ST	P04637	TP53	P50750	CDK9	S313	L308M	308	Missense	distal	-5	no	2.130	2.239	EPSD	COSMIC	1.932	Up-regulation
CMGC_CDK_CDK9_CDK9_ST	P04637	TP53	P50750	CDK9	S313	S313C	313	Missense	central	0	yes	2.130	0.000	EPSD	COSMIC	1.932	Loss
CMGC_CDK_CDK9_CDK9_ST	P04637	TP53	P50750	CDK9	S313	N311H	311	Missense	proximal	-2	no	2.130	1.867	EPSD	COSMIC	1.932	Loss
CMGC_CDK_CDK9_CDK9_ST	P04637	TP53	P50750	CDK9	S313	L308V	308	Missense	distal	-5	no	2.130	2.170	EPSD	COSMIC	1.932	Up-regulation
CMGC_CDK_CDK9_CDK9_ST	P04637	TP53	P50750	CDK9	S313	S314F	314	Missense	proximal	1	no	2.130	0.828	EPSD	COSMIC	1.932	Loss
CMGC_CDK_CDK9_CDK9_ST	P04637	TP53	P50750	CDK9	S313	K319R	319	Missense	distal	6	no	2.130	2.073	EPSD	COSMIC	1.932	Down-regulation
CMGC_CDK_CDK9_CDK9_ST	P04637	TP53	P50750	CDK9	S313	T312A	312	Missense	proximal	-1	no	2.130	2.107	EPSD	COSMIC	1.932	Down-regulation
CMGC_CDK_CDK9_CDK9_ST	P04637	TP53	P50750	CDK9	S313	N310D	310	Missense	distal	-3	no	2.130	2.172	EPSD	COSMIC	1.932	Up-regulation
CMGC_CDK_CDK9_CDK9_ST	P04637	TP53	P50750	CDK9	S313	N311D	311	Missense	proximal	-2	no	2.130	1.798	EPSD	COSMIC	1.932	Loss
CMGC_CDK_CDK9_CDK9_ST	P04637	TP53	P50750	CDK9	S313	P309R	309	Missense	distal	-4	no	2.130	2.035	EPSD	COSMIC	1.932	Down-regulation
CMGC_CDK_CDK9_CDK9_ST	P04637	TP53	P50750	CDK9	S313	S313N	313	Missense	central	0	yes	2.130	0.000	EPSD	COSMIC	1.932	Loss
CMGC_CDK_CDK9_CDK9_ST	P04637	TP53	P50750	CDK9	S313	Q317P	317	Missense	distal	4	no	2.130	2.099	EPSD	COSMIC	1.932	Down-regulation
CMGC_CDK_CDK9_CDK9_ST	P04637	TP53	P50750	CDK9	S313	A307S	307	Missense	distal	-6	no	2.130	2.526	EPSD	COSMIC	1.932	Up-regulation
CMGC_CDK_CDK9_CDK9_ST	P04637	TP53	P50750	CDK9	S313	P316S	316	Missense	distal	3	no	2.130	2.096	EPSD	COSMIC	1.932	Down-regulation
CMGC_CDK_CDK9_CDK9_ST	P04637	TP53	P50750	CDK9	S314	S315P	315	Missense	proximal	1	no	1.138	4.872	EPSD	COSMIC	1.932	Gain
CMGC_CDK_CDK9_CDK9_ST	P04637	TP53	P50750	CDK9	S315	N310T	310	Missense	distal	-5	no	5.402	5.346	EPSD;PhosphoSitePlus	COSMIC	1.932	Down-regulation
CMGC_CDK_CDK9_CDK9_ST	P04637	TP53	P50750	CDK9	S315	Q317R	317	Missense	proximal	2	no	5.402	5.448	EPSD;PhosphoSitePlus	COSMIC	1.932	Up-regulation
CMGC_CDK_CDK9_CDK9_ST	P04637	TP53	P50750	CDK9	S315	P309S	309	Missense	distal	-6	no	5.402	5.270	EPSD;PhosphoSitePlus	COSMIC;GDSC;CCLE	1.932	Down-regulation
CMGC_CDK_CDK9_CDK9_ST	P04637	TP53	P50750	CDK9	S315	K319E	319	Missense	distal	4	no	5.402	5.393	EPSD;PhosphoSitePlus	COSMIC	1.932	Down-regulation
CMGC_CDK_CDK9_CDK9_ST	P04637	TP53	P50750	CDK9	S315	P322L	322	Missense	distal	7	no	5.402	5.665	EPSD;PhosphoSitePlus	COSMIC	1.932	Up-regulation
CMGC_CDK_CDK9_CDK9_ST	P04637	TP53	P50750	CDK9	S315	K320N	320	Missense	distal	5	no	5.402	5.483	EPSD;PhosphoSitePlus	COSMIC;GDSC;CCLE	1.932	Up-regulation
CMGC_CDK_CDK9_CDK9_ST	P04637	TP53	P50750	CDK9	S315	N310L	310	Missense	distal	-5	no	5.402	5.167	EPSD;PhosphoSitePlus	COSMIC	1.932	Down-regulation
CMGC_CDK_CDK9_CDK9_ST	P04637	TP53	P50750	CDK9	S315	T312S	312	Missense	distal	-3	no	5.402	5.347	EPSD;PhosphoSitePlus	COSMIC	1.932	Down-regulation
CMGC_CDK_CDK9_CDK9_ST	P04637	TP53	P50750	CDK9	S315	N311Y	311	Missense	distal	-4	no	5.402	5.335	EPSD;PhosphoSitePlus	COSMIC	1.932	Down-regulation
CMGC_CDK_CDK9_CDK9_ST	P04637	TP53	P50750	CDK9	S315	P322R	322	Missense	distal	7	no	5.402	5.593	EPSD;PhosphoSitePlus	COSMIC	1.932	Up-regulation
CMGC_CDK_CDK9_CDK9_ST	P04637	TP53	P50750	CDK9	S315	N311K	311	Missense	distal	-4	no	5.402	5.371	EPSD;PhosphoSitePlus	COSMIC	1.932	Down-regulation
CMGC_CDK_CDK9_CDK9_ST	P04637	TP53	P50750	CDK9	S315	Q317K	317	Missense	proximal	2	no	5.402	5.425	EPSD;PhosphoSitePlus	COSMIC	1.932	Up-regulation
CMGC_CDK_CDK9_CDK9_ST	P04637	TP53	P50750	CDK9	S315	S315P	315	Missense	central	0	yes	5.402	0.000	EPSD;PhosphoSitePlus	COSMIC	1.932	Loss
CMGC_CDK_CDK9_CDK9_ST	P04637	TP53	P50750	CDK9	S315	N310H	310	Missense	distal	-5	no	5.402	5.272	EPSD;PhosphoSitePlus	COSMIC	1.932	Down-regulation
CMGC_CDK_CDK9_CDK9_ST	P04637	TP53	P50750	CDK9	S315	S314C	314	Missense	proximal	-1	no	5.402	5.322	EPSD;PhosphoSitePlus	COSMIC	1.932	Down-regulation
CMGC_CDK_CDK9_CDK9_ST	P04637	TP53	P50750	CDK9	S315	P318A	318	Missense	distal	3	no	5.402	5.100	EPSD;PhosphoSitePlus	COSMIC	1.932	Down-regulation
CMGC_CDK_CDK9_CDK9_ST	P04637	TP53	P50750	CDK9	S315	P316L	316	Missense	proximal	1	no	5.402	-0.196	EPSD;PhosphoSitePlus	COSMIC	1.932	Loss
CMGC_CDK_CDK9_CDK9_ST	P04637	TP53	P50750	CDK9	S315	L308M	308	Missense	distal	-7	no	5.402	5.388	EPSD;PhosphoSitePlus	COSMIC	1.932	Down-regulation
CMGC_CDK_CDK9_CDK9_ST	P04637	TP53	P50750	CDK9	S315	S313C	313	Missense	proximal	-2	no	5.402	4.876	EPSD;PhosphoSitePlus	COSMIC	1.932	Down-regulation
CMGC_CDK_CDK9_CDK9_ST	P04637	TP53	P50750	CDK9	S315	N311H	311	Missense	distal	-4	no	5.402	5.345	EPSD;PhosphoSitePlus	COSMIC	1.932	Down-regulation
CMGC_CDK_CDK9_CDK9_ST	P04637	TP53	P50750	CDK9	S315	L308V	308	Missense	distal	-7	no	5.402	5.393	EPSD;PhosphoSitePlus	COSMIC	1.932	Down-regulation
CMGC_CDK_CDK9_CDK9_ST	P04637	TP53	P50750	CDK9	S315	S314F	314	Missense	proximal	-1	no	5.402	5.323	EPSD;PhosphoSitePlus	COSMIC	1.932	Down-regulation
CMGC_CDK_CDK9_CDK9_ST	P04637	TP53	P50750	CDK9	S315	K319R	319	Missense	distal	4	no	5.402	5.393	EPSD;PhosphoSitePlus	COSMIC	1.932	Down-regulation
CMGC_CDK_CDK9_CDK9_ST	P04637	TP53	P50750	CDK9	S315	T312A	312	Missense	distal	-3	no	5.402	5.435	EPSD;PhosphoSitePlus	COSMIC	1.932	Up-regulation
CMGC_CDK_CDK9_CDK9_ST	P04637	TP53	P50750	CDK9	S315	N310D	310	Missense	distal	-5	no	5.402	5.186	EPSD;PhosphoSitePlus	COSMIC	1.932	Down-regulation
CMGC_CDK_CDK9_CDK9_ST	P04637	TP53	P50750	CDK9	S315	N311D	311	Missense	distal	-4	no	5.402	5.326	EPSD;PhosphoSitePlus	COSMIC	1.932	Down-regulation
CMGC_CDK_CDK9_CDK9_ST	P04637	TP53	P50750	CDK9	S315	P309R	309	Missense	distal	-6	no	5.402	4.982	EPSD;PhosphoSitePlus	COSMIC	1.932	Down-regulation
CMGC_CDK_CDK9_CDK9_ST	P04637	TP53	P50750	CDK9	S315	S313N	313	Missense	proximal	-2	no	5.402	5.276	EPSD;PhosphoSitePlus	COSMIC	1.932	Down-regulation
CMGC_CDK_CDK9_CDK9_ST	P04637	TP53	P50750	CDK9	S315	Q317P	317	Missense	proximal	2	no	5.402	5.342	EPSD;PhosphoSitePlus	COSMIC	1.932	Down-regulation
CMGC_CDK_CDK9_CDK9_ST	P04637	TP53	P50750	CDK9	S315	P316S	316	Missense	proximal	1	no	5.402	1.668	EPSD;PhosphoSitePlus	COSMIC	1.932	Loss
CMGC_CDK_CDK9_CDK9_ST	P04637	TP53	P50750	CDK9	S371	S378F	378	Missense	distal	7	no	1.624	1.953	EPSD	COSMIC	1.932	Gain
CMGC_CDK_CDK9_CDK9_ST	P04637	TP53	P50750	CDK9	S376	K370N	370	Missense	distal	-6	no	1.885	1.974	EPSD	COSMIC	1.932	Gain
CMGC_CDK_CDK9_CDK9_ST	P04637	TP53	P50750	CDK9	S376	S378F	378	Missense	proximal	2	no	1.885	2.088	EPSD	COSMIC	1.932	Gain
CMGC_CDK_CDK9_CDK9_ST	P04637	TP53	P50750	CDK9	S376	K370Q	370	Missense	distal	-6	no	1.885	1.998	EPSD	COSMIC	1.932	Gain
CMGC_CDK_CDK9_CDK9_ST	P04637	TP53	P50750	CDK9	S376	K381N	381	Missense	distal	5	no	1.885	1.966	EPSD	COSMIC	1.932	Gain
CMGC_CDK_CDK9_CDK9_ST	P04637	TP53	P50750	CDK9	S376	R379P	379	Missense	distal	3	no	1.885	2.125	EPSD	COSMIC	1.932	Gain
CMGC_CDK_CDK9_CDK9_ST	P04637	TP53	P50750	CDK9	S376	G374S	374	Missense	proximal	-2	no	1.885	2.316	EPSD	COSMIC	1.932	Gain
CMGC_CDK_CDK9_CDK9_ST	P04637	TP53	P50750	CDK9	T377	K370N	370	Missense	distal	-7	no	2.722	2.710	EPSD	COSMIC	1.932	Down-regulation
CMGC_CDK_CDK9_CDK9_ST	P04637	TP53	P50750	CDK9	T377	L383F	383	Missense	distal	6	no	2.722	2.703	EPSD	COSMIC	1.932	Down-regulation
CMGC_CDK_CDK9_CDK9_ST	P04637	TP53	P50750	CDK9	T377	R379H	379	Missense	proximal	2	no	2.722	2.734	EPSD	COSMIC	1.932	Up-regulation
CMGC_CDK_CDK9_CDK9_ST	P04637	TP53	P50750	CDK9	T377	S376T	376	Missense	proximal	-1	no	2.722	2.673	EPSD	COSMIC	1.932	Down-regulation
CMGC_CDK_CDK9_CDK9_ST	P04637	TP53	P50750	CDK9	T377	H380Y	380	Missense	distal	3	no	2.722	2.696	EPSD	COSMIC	1.932	Down-regulation
CMGC_CDK_CDK9_CDK9_ST	P04637	TP53	P50750	CDK9	T377	T377I	377	Missense	central	0	yes	2.722	0.000	EPSD	COSMIC	1.932	Loss
CMGC_CDK_CDK9_CDK9_ST	P04637	TP53	P50750	CDK9	T377	S378F	378	Missense	proximal	1	no	2.722	1.419	EPSD	COSMIC	1.932	Loss
CMGC_CDK_CDK9_CDK9_ST	P04637	TP53	P50750	CDK9	T377	K370Q	370	Missense	distal	-7	no	2.722	2.709	EPSD	COSMIC	1.932	Down-regulation
CMGC_CDK_CDK9_CDK9_ST	P04637	TP53	P50750	CDK9	T377	K381N	381	Missense	distal	4	no	2.722	2.745	EPSD	COSMIC	1.932	Up-regulation
CMGC_CDK_CDK9_CDK9_ST	P04637	TP53	P50750	CDK9	T377	R379P	379	Missense	proximal	2	no	2.722	2.616	EPSD	COSMIC	1.932	Down-regulation
CMGC_CDK_CDK9_CDK9_ST	P04637	TP53	P50750	CDK9	T377	M384I	384	Missense	distal	7	no	2.722	2.768	EPSD	COSMIC	1.932	Up-regulation
CMGC_CDK_CDK9_CDK9_ST	P04637	TP53	P50750	CDK9	T377	K373R	373	Missense	distal	-4	no	2.722	2.711	EPSD	COSMIC	1.932	Down-regulation
CMGC_CDK_CDK9_CDK9_ST	P04637	TP53	P50750	CDK9	T377	S376F	376	Missense	proximal	-1	no	2.722	2.643	EPSD	COSMIC	1.932	Down-regulation
CMGC_CDK_CDK9_CDK9_ST	P04637	TP53	P50750	CDK9	T377	G374S	374	Missense	distal	-3	no	2.722	2.640	EPSD	COSMIC	1.932	Down-regulation
CMGC_CDK_CDK9_CDK9_ST	P04637	TP53	P50750	CDK9	T377	S376A	376	Missense	proximal	-1	no	2.722	2.650	EPSD	COSMIC	1.932	Down-regulation
CMGC_CDK_CDK9_CDK9_ST	P04637	TP53	P50750	CDK9	T377	S371P	371	Missense	distal	-6	no	2.722	2.854	EPSD	COSMIC	1.932	Up-regulation
CMGC_CDK_CDK9_CDK9_ST	P04637	TP53	P50750	CDK9	S378	L383F	383	Missense	distal	5	no	2.329	2.297	EPSD	COSMIC	1.932	Down-regulation
CMGC_CDK_CDK9_CDK9_ST	P04637	TP53	P50750	CDK9	S378	R379H	379	Missense	proximal	1	no	2.329	1.931	EPSD	COSMIC	1.932	Loss
CMGC_CDK_CDK9_CDK9_ST	P04637	TP53	P50750	CDK9	S378	S376T	376	Missense	proximal	-2	no	2.329	2.076	EPSD	COSMIC	1.932	Down-regulation
CMGC_CDK_CDK9_CDK9_ST	P04637	TP53	P50750	CDK9	S378	H380Y	380	Missense	proximal	2	no	2.329	2.367	EPSD	COSMIC	1.932	Up-regulation
CMGC_CDK_CDK9_CDK9_ST	P04637	TP53	P50750	CDK9	S378	T377I	377	Missense	proximal	-1	no	2.329	2.309	EPSD	COSMIC	1.932	Down-regulation
CMGC_CDK_CDK9_CDK9_ST	P04637	TP53	P50750	CDK9	S378	S378F	378	Missense	central	0	yes	2.329	0.000	EPSD	COSMIC	1.932	Loss
CMGC_CDK_CDK9_CDK9_ST	P04637	TP53	P50750	CDK9	S378	K381N	381	Missense	distal	3	no	2.329	2.364	EPSD	COSMIC	1.932	Up-regulation
CMGC_CDK_CDK9_CDK9_ST	P04637	TP53	P50750	CDK9	S378	R379P	379	Missense	proximal	1	no	2.329	6.505	EPSD	COSMIC	1.932	Up-regulation
CMGC_CDK_CDK9_CDK9_ST	P04637	TP53	P50750	CDK9	S378	M384I	384	Missense	distal	6	no	2.329	2.244	EPSD	COSMIC	1.932	Down-regulation
CMGC_CDK_CDK9_CDK9_ST	P04637	TP53	P50750	CDK9	S378	K373R	373	Missense	distal	-5	no	2.329	2.290	EPSD	COSMIC	1.932	Down-regulation
CMGC_CDK_CDK9_CDK9_ST	P04637	TP53	P50750	CDK9	S378	S376F	376	Missense	proximal	-2	no	2.329	1.810	EPSD	COSMIC	1.932	Loss
CMGC_CDK_CDK9_CDK9_ST	P04637	TP53	P50750	CDK9	S378	G374S	374	Missense	distal	-4	no	2.329	2.448	EPSD	COSMIC	1.932	Up-regulation
CMGC_CDK_CDK9_CDK9_ST	P04637	TP53	P50750	CDK9	S378	S376A	376	Missense	proximal	-2	no	2.329	1.867	EPSD	COSMIC	1.932	Loss
CMGC_CDK_CDK9_CDK9_ST	P04637	TP53	P50750	CDK9	S378	S371P	371	Missense	distal	-7	no	2.329	2.325	EPSD	COSMIC	1.932	Down-regulation
CMGC_CDK_CDK9_CDK9_ST	P04637	TP53	P50750	CDK9	T387	K381N	381	Missense	distal	-6	no	1.910	1.999	EPSD	COSMIC	1.932	Gain
CMGC_CDK_CDK9_CDK9_ST	P04637	TP53	P50750	CDK9	T387	D391N	391	Missense	distal	4	no	1.910	1.972	EPSD	COSMIC	1.932	Gain
CAMK_CAMKL_MELK_MELK_ST	Q14680	MELK	Q14680	MELK	T56	I58T	58	Missense	proximal	2	no	244.425	249.059	EPSD;PhosphoSitePlus	COSMIC	155.919	Up-regulation
CAMK_CAMKL_MELK_MELK_ST	Q14680	MELK	Q14680	MELK	T56	R53Q	53	Missense	distal	-3	no	244.425	210.729	EPSD;PhosphoSitePlus	COSMIC	155.919	Down-regulation
CAMK_CAMKL_MELK_MELK_ST	Q14680	MELK	Q14680	MELK	T56	R53P	53	Missense	distal	-3	no	244.425	222.034	EPSD;PhosphoSitePlus	COSMIC	155.919	Down-regulation
CAMK_CAMKL_MELK_MELK_ST	Q14680	MELK	Q14680	MELK	T167	H164N	164	Missense	distal	-3	no	235.306	253.067	EPSD;PhosphoSitePlus	COSMIC	155.919	Up-regulation
CAMK_CAMKL_MELK_MELK_ST	Q14680	MELK	Q14680	MELK	T167	Y163H	163	Missense	distal	-4	no	235.306	236.764	EPSD;PhosphoSitePlus	COSMIC	155.919	Up-regulation
CAMK_CAMKL_MELK_MELK_ST	Q14680	MELK	Q14680	MELK	T167	Q166L	166	Missense	proximal	-1	no	235.306	230.580	EPSD;PhosphoSitePlus	COSMIC	155.919	Down-regulation
CAMK_CAMKL_MELK_MELK_ST	Q14680	MELK	Q14680	MELK	S171	H164N	164	Missense	distal	-7	no	219.497	249.036	EPSD;PhosphoSitePlus	COSMIC	155.919	Up-regulation
CAMK_CAMKL_MELK_MELK_ST	Q14680	MELK	Q14680	MELK	S171	A175V	175	Missense	distal	4	no	219.497	215.606	EPSD;PhosphoSitePlus	COSMIC	155.919	Down-regulation
CAMK_CAMKL_MELK_MELK_ST	Q14680	MELK	Q14680	MELK	S171	Q166L	166	Missense	distal	-5	no	219.497	219.372	EPSD;PhosphoSitePlus	COSMIC	155.919	Down-regulation
CAMK_CAMKL_MELK_MELK_ST	Q14680	MELK	Q14680	MELK	S253	S253C	253	Missense	central	0	yes	226.646	0.000	EPSD;PhosphoSitePlus	COSMIC	155.919	Loss
CAMK_CAMKL_MELK_MELK_ST	Q14680	MELK	Q14680	MELK	S253	M254I	254	Missense	proximal	1	no	226.646	227.987	EPSD;PhosphoSitePlus	COSMIC	155.919	Up-regulation
CAMK_CAMKL_MELK_MELK_ST	Q14680	MELK	Q14680	MELK	S253	S253Y	253	Missense	central	0	yes	226.646	0.000	EPSD;PhosphoSitePlus	COSMIC;GDSC;CCLE	155.919	Loss
CAMK_CAMKL_MELK_MELK_ST	Q14680	MELK	Q14680	MELK	S336	P329S	329	Missense	distal	-7	no	246.493	253.802	EPSD;PhosphoSitePlus	COSMIC	155.919	Up-regulation
CAMK_CAMKL_MELK_MELK_ST	Q14680	MELK	Q14680	MELK	S343	T345I	345	Missense	proximal	2	no	217.006	212.371	EPSD;PhosphoSitePlus	COSMIC	155.919	Down-regulation
CAMK_CAMKL_MELK_MELK_ST	Q14680	MELK	Q14680	MELK	S343	T348I	348	Missense	distal	5	no	217.006	184.465	EPSD;PhosphoSitePlus	COSMIC	155.919	Down-regulation
CAMK_CAMKL_MELK_MELK_ST	Q14680	MELK	Q14680	MELK	S343	P346L	346	Missense	distal	3	no	217.006	215.809	EPSD;PhosphoSitePlus	COSMIC	155.919	Down-regulation
CAMK_CAMKL_MELK_MELK_ST	Q14680	MELK	Q14680	MELK	S356	S352P	352	Missense	distal	-4	no	215.772	214.713	EPSD;PhosphoSitePlus	COSMIC	155.919	Down-regulation
CAMK_CAMKL_MELK_MELK_ST	Q14680	MELK	Q14680	MELK	S356	A362P	362	Missense	distal	6	no	215.772	216.387	EPSD;PhosphoSitePlus	COSMIC	155.919	Up-regulation
CAMK_CAMKL_MELK_MELK_ST	Q14680	MELK	Q14680	MELK	S356	A362T	362	Missense	distal	6	no	215.772	216.792	EPSD;PhosphoSitePlus	COSMIC	155.919	Up-regulation
CAMK_CAMKL_MELK_MELK_ST	Q14680	MELK	Q14680	MELK	T387	P388S	388	Missense	proximal	1	no	211.694	208.286	EPSD;PhosphoSitePlus	COSMIC	155.919	Down-regulation
CAMK_CAMKL_MELK_MELK_ST	Q14680	MELK	Q14680	MELK	T387	T387A	387	Missense	central	0	yes	211.694	0.000	EPSD;PhosphoSitePlus	COSMIC	155.919	Loss
CAMK_CAMKL_MELK_MELK_ST	Q14680	MELK	Q14680	MELK	T387	P388L	388	Missense	proximal	1	no	211.694	210.731	EPSD;PhosphoSitePlus	COSMIC	155.919	Down-regulation
CAMK_CAMKL_MELK_MELK_ST	Q14680	MELK	Q14680	MELK	S391	P388S	388	Missense	distal	-3	no	225.428	217.193	EPSD;PhosphoSitePlus	COSMIC	155.919	Down-regulation
CAMK_CAMKL_MELK_MELK_ST	Q14680	MELK	Q14680	MELK	S391	T387A	387	Missense	distal	-4	no	225.428	224.396	EPSD;PhosphoSitePlus	COSMIC	155.919	Down-regulation
CAMK_CAMKL_MELK_MELK_ST	Q14680	MELK	Q14680	MELK	S391	P388L	388	Missense	distal	-3	no	225.428	216.499	EPSD;PhosphoSitePlus	COSMIC	155.919	Down-regulation
CAMK_CAMKL_MELK_MELK_ST	Q14680	MELK	Q14680	MELK	T398	S400P	400	Missense	proximal	2	no	290.214	291.551	EPSD;PhosphoSitePlus	COSMIC	155.919	Up-regulation
CAMK_CAMKL_MELK_MELK_ST	Q14680	MELK	Q14680	MELK	T398	E404G	404	Missense	distal	6	no	290.214	289.084	EPSD;PhosphoSitePlus	COSMIC	155.919	Down-regulation
CAMK_CAMKL_MELK_MELK_ST	Q14680	MELK	Q14680	MELK	T398	E404K	404	Missense	distal	6	no	290.214	293.951	EPSD;PhosphoSitePlus	COSMIC	155.919	Up-regulation
CAMK_CAMKL_MELK_MELK_ST	Q14680	MELK	Q14680	MELK	S405	S400P	400	Missense	distal	-5	no	228.928	221.324	EPSD;PhosphoSitePlus	COSMIC	155.919	Down-regulation
CAMK_CAMKL_MELK_MELK_ST	Q14680	MELK	Q14680	MELK	S405	E404G	404	Missense	proximal	-1	no	228.928	234.989	EPSD;PhosphoSitePlus	COSMIC	155.919	Up-regulation
CAMK_CAMKL_MELK_MELK_ST	Q14680	MELK	Q14680	MELK	S405	E404K	404	Missense	proximal	-1	no	228.928	219.654	EPSD;PhosphoSitePlus	COSMIC	155.919	Down-regulation
CAMK_CAMKL_MELK_MELK_ST	Q14680	MELK	Q14680	MELK	S407	S400P	400	Missense	distal	-7	no	217.069	209.760	EPSD;PhosphoSitePlus	COSMIC	155.919	Down-regulation
CAMK_CAMKL_MELK_MELK_ST	Q14680	MELK	Q14680	MELK	S407	E404G	404	Missense	distal	-3	no	217.069	245.013	EPSD;PhosphoSitePlus	COSMIC	155.919	Up-regulation
CAMK_CAMKL_MELK_MELK_ST	Q14680	MELK	Q14680	MELK	S407	E404K	404	Missense	distal	-3	no	217.069	264.557	EPSD;PhosphoSitePlus	COSMIC	155.919	Up-regulation
CAMK_CAMKL_MELK_MELK_ST	Q14680	MELK	Q14680	MELK	T409	E404G	404	Missense	distal	-5	no	228.999	224.856	EPSD;PhosphoSitePlus	COSMIC	155.919	Down-regulation
CAMK_CAMKL_MELK_MELK_ST	Q14680	MELK	Q14680	MELK	T409	E404K	404	Missense	distal	-5	no	228.999	230.777	EPSD;PhosphoSitePlus	COSMIC	155.919	Up-regulation
CAMK_CAMKL_MELK_MELK_ST	Q14680	MELK	Q14680	MELK	S431	E437V	437	Missense	distal	6	no	216.244	217.332	EPSD;PhosphoSitePlus	COSMIC	155.919	Up-regulation
CAMK_CAMKL_MELK_MELK_ST	Q14680	MELK	Q14680	MELK	S431	K434N	434	Missense	distal	3	no	216.244	213.869	EPSD;PhosphoSitePlus	COSMIC	155.919	Down-regulation
CAMK_CAMKL_MELK_MELK_ST	Q14680	MELK	Q14680	MELK	S431	A432D	432	Missense	proximal	1	no	216.244	214.025	EPSD;PhosphoSitePlus	COSMIC	155.919	Down-regulation
CAMK_CAMKL_MELK_MELK_ST	Q14680	MELK	Q14680	MELK	S431	E436K	436	Missense	distal	5	no	216.244	215.624	EPSD;PhosphoSitePlus	COSMIC	155.919	Down-regulation
CAMK_CAMKL_MELK_MELK_ST	Q14680	MELK	Q14680	MELK	S431	T428M	428	Missense	distal	-3	no	216.244	231.511	EPSD;PhosphoSitePlus	COSMIC	155.919	Up-regulation
CAMK_CAMKL_MELK_MELK_ST	Q14680	MELK	Q14680	MELK	S505	S505L	505	Missense	central	0	yes	229.693	0.000	EPSD;PhosphoSitePlus	COSMIC	155.919	Loss
CAMK_CAMKL_MELK_MELK_ST	Q14680	MELK	Q14680	MELK	S505	R502W	502	Missense	distal	-3	no	229.693	182.257	EPSD;PhosphoSitePlus	COSMIC;GDSC	155.919	Down-regulation
CAMK_CAMKL_MELK_MELK_ST	Q14680	MELK	Q14680	MELK	S505	Q512E	512	Missense	distal	7	no	229.693	216.757	EPSD;PhosphoSitePlus	COSMIC	155.919	Down-regulation
CAMK_CAMKL_MELK_MELK_ST	Q14680	MELK	Q14680	MELK	S529	K536N	536	Missense	distal	7	no	223.112	233.786	EPSD;PhosphoSitePlus	COSMIC	155.919	Up-regulation
CAMK_CAMKL_MELK_MELK_ST	Q14680	MELK	Q14680	MELK	S529	G528R	528	Missense	proximal	-1	no	223.112	213.683	EPSD;PhosphoSitePlus	COSMIC;GDSC;CCLE	155.919	Down-regulation
CAMK_CAMKL_MELK_MELK_ST	Q14680	MELK	Q14680	MELK	S529	G528V	528	Missense	proximal	-1	no	223.112	212.237	EPSD;PhosphoSitePlus	COSMIC	155.919	Down-regulation
CAMK_CAMKL_MELK_MELK_ST	Q14680	MELK	Q14680	MELK	T539	S544N	544	Missense	distal	5	no	236.033	237.990	EPSD;PhosphoSitePlus	COSMIC	155.919	Up-regulation
CAMK_CAMKL_MELK_MELK_ST	Q14680	MELK	Q14680	MELK	T539	L541F	541	Missense	proximal	2	no	236.033	232.331	EPSD;PhosphoSitePlus	COSMIC	155.919	Down-regulation
CAMK_CAMKL_MELK_MELK_ST	Q14680	MELK	Q14680	MELK	T539	K536N	536	Missense	distal	-3	no	236.033	221.526	EPSD;PhosphoSitePlus	COSMIC	155.919	Down-regulation
CAMK_CAMKL_MELK_MELK_ST	P30305	CDC25B	Q14680	MELK	S67	E68K	68	Missense	proximal	1	no	156.366	154.362	EPSD	COSMIC	155.919	Loss
CAMK_CAMKL_MELK_MELK_ST	P30305	CDC25B	Q14680	MELK	S67	Q73H	73	Missense	distal	6	no	156.366	158.567	EPSD	COSMIC	155.919	Up-regulation
CAMK_CAMKL_MELK_MELK_ST	P30305	CDC25B	Q14680	MELK	T69	E68K	68	Missense	proximal	-1	no	172.298	163.024	EPSD	COSMIC	155.919	Down-regulation
CAMK_CAMKL_MELK_MELK_ST	P30305	CDC25B	Q14680	MELK	T69	Q73H	73	Missense	distal	4	no	172.298	170.277	EPSD	COSMIC	155.919	Down-regulation
CAMK_CAMKL_MELK_MELK_ST	P30305	CDC25B	Q14680	MELK	S91	R93W	93	Missense	proximal	2	no	158.041	142.864	EPSD	COSMIC	155.919	Loss
CAMK_CAMKL_MELK_MELK_ST	P30305	CDC25B	Q14680	MELK	S91	S89P	89	Missense	proximal	-2	no	158.041	153.381	EPSD	COSMIC	155.919	Loss
CAMK_CAMKL_MELK_MELK_ST	P30305	CDC25B	Q14680	MELK	S169	V162L	162	Missense	distal	-7	no	213.004	208.183	PhosphoSitePlus;EPSD	COSMIC	155.919	Down-regulation
CAMK_CAMKL_MELK_MELK_ST	P30305	CDC25B	Q14680	MELK	S169	R175Q	175	Missense	distal	6	no	213.004	209.505	PhosphoSitePlus;EPSD	COSMIC;GDSC	155.919	Down-regulation
CAMK_CAMKL_MELK_MELK_ST	P30305	CDC25B	Q14680	MELK	S323	S323N	323	Missense	central	0	yes	225.877	0.000	EPSD;PhosphoSitePlus	COSMIC	155.919	Loss
CAMK_CAMKL_MELK_MELK_ST	P30305	CDC25B	Q14680	MELK	S323	P325L	325	Missense	proximal	2	no	225.877	227.658	EPSD;PhosphoSitePlus	COSMIC	155.919	Up-regulation
CAMK_CAMKL_MELK_MELK_ST	P30305	CDC25B	Q14680	MELK	S323	R320G	320	Missense	distal	-3	no	225.877	223.555	EPSD;PhosphoSitePlus	COSMIC	155.919	Down-regulation
CAMK_CAMKL_MELK_MELK_ST	P30305	CDC25B	Q14680	MELK	S323	S321F	321	Missense	proximal	-2	no	225.877	220.706	EPSD;PhosphoSitePlus	COSMIC	155.919	Down-regulation
CAMK_CAMKL_MELK_MELK_ST	P30305	CDC25B	Q14680	MELK	S323	R330Q	330	Missense	distal	7	no	225.877	219.152	EPSD;PhosphoSitePlus	COSMIC	155.919	Down-regulation
CAMK_CAMKL_MELK_MELK_ST	P30305	CDC25B	Q14680	MELK	S323	P322L	322	Missense	proximal	-1	no	225.877	224.007	EPSD;PhosphoSitePlus	COSMIC	155.919	Down-regulation
CAMK_CAMKL_MELK_MELK_ST	P30305	CDC25B	Q14680	MELK	S323	R317W	317	Missense	distal	-6	no	225.877	233.834	EPSD;PhosphoSitePlus	COSMIC	155.919	Up-regulation
CAMK_CAMKL_MELK_MELK_ST	P30305	CDC25B	Q14680	MELK	S470	E464G	464	Missense	distal	-6	no	156.622	160.044	EPSD	COSMIC	155.919	Up-regulation
CAMK_CAMKL_MELK_MELK_ST	P30305	CDC25B	Q14680	MELK	S470	E464K	464	Missense	distal	-6	no	156.622	150.750	EPSD	COSMIC	155.919	Loss
CAMK_CAMKL_MELK_MELK_ST	P30305	CDC25B	Q14680	MELK	S470	L477P	477	Missense	distal	7	no	156.622	126.722	EPSD	COSMIC	155.919	Loss
CAMK_CAMKL_MELK_MELK_ST	P30305	CDC25B	Q14680	MELK	S470	A473V	473	Missense	distal	3	no	156.622	150.785	EPSD	COSMIC	155.919	Loss
CAMK_CAMKL_MELK_MELK_ST	P30305	CDC25B	Q14680	MELK	S470	A463T	463	Missense	distal	-7	no	156.622	168.465	EPSD	COSMIC	155.919	Up-regulation
CAMK_CAMKL_MELK_MELK_ST	P30305	CDC25B	Q14680	MELK	S470	K469R	469	Missense	proximal	-1	no	156.622	162.528	EPSD	COSMIC	155.919	Up-regulation
CAMK_CAMKL_MELK_MELK_ST	P30305	CDC25B	Q14680	MELK	S563	R562W	562	Missense	proximal	-1	no	165.448	182.721	EPSD	COSMIC	155.919	Up-regulation
CAMK_CAMKL_MELK_MELK_ST	P30305	CDC25B	Q14680	MELK	S563	T556I	556	Missense	distal	-7	no	165.448	156.601	EPSD	COSMIC	155.919	Down-regulation
CAMK_CAMKL_MELK_MELK_ST	P30305	CDC25B	Q14680	MELK	S563	R568Q	568	Missense	distal	5	no	165.448	162.988	EPSD	COSMIC	155.919	Down-regulation
CAMK_CAMKL_MELK_MELK_ST	P30305	CDC25B	Q14680	MELK	S563	R570W	570	Missense	distal	7	no	165.448	132.160	EPSD	COSMIC	155.919	Loss
CAMK_CAMKL_MELK_MELK_ST	P30305	CDC25B	Q14680	MELK	S563	R558H	558	Missense	distal	-5	no	165.448	157.111	EPSD	COSMIC	155.919	Down-regulation
CAMK_CAMKL_MELK_MELK_ST	P30305	CDC25B	Q14680	MELK	S563	K560R	560	Missense	distal	-3	no	165.448	148.226	EPSD	COSMIC	155.919	Loss
CAMK_CAMKL_MELK_MELK_ST	P30305	CDC25B	Q14680	MELK	S563	R570L	570	Missense	distal	7	no	165.448	171.592	EPSD	COSMIC	155.919	Up-regulation
CAMK_CAMKL_MELK_MELK_ST	P23588	EIF4B	Q14680	MELK	S57	T54S	54	Missense	distal	-3	no	170.173	167.269	EPSD	COSMIC	155.919	Down-regulation
CAMK_CAMKL_MELK_MELK_ST	P23588	EIF4B	Q14680	MELK	S192	W199R	199	Missense	distal	7	no	143.960	177.248	EPSD	COSMIC;GDSC;CCLE	155.919	Gain
CAMK_CAMKL_MELK_MELK_ST	P23588	EIF4B	Q14680	MELK	S263	D260G	260	Missense	distal	-3	no	136.994	157.093	EPSD	COSMIC	155.919	Gain
CAMK_CAMKL_MELK_MELK_ST	P23588	EIF4B	Q14680	MELK	S276	R273W	273	Missense	distal	-3	no	161.934	114.498	EPSD	COSMIC	155.919	Loss
CAMK_CAMKL_MELK_MELK_ST	P23588	EIF4B	Q14680	MELK	S276	I274T	274	Missense	proximal	-2	no	161.934	169.385	EPSD	COSMIC;GDSC;CCLE	155.919	Up-regulation
CAMK_CAMKL_MELK_MELK_ST	P23588	EIF4B	Q14680	MELK	S311	S309L	309	Missense	proximal	-2	no	165.366	165.197	EPSD	COSMIC	155.919	Down-regulation
CAMK_CAMKL_MELK_MELK_ST	P23588	EIF4B	Q14680	MELK	S311	R308W	308	Missense	distal	-3	no	165.366	117.930	EPSD	COSMIC	155.919	Loss
CAMK_CAMKL_MELK_MELK_ST	P23588	EIF4B	Q14680	MELK	S311	Y316C	316	Missense	distal	5	no	165.366	144.994	EPSD	COSMIC	155.919	Loss
CAMK_CAMKL_MELK_MELK_ST	P23588	EIF4B	Q14680	MELK	S311	R305W	305	Missense	distal	-6	no	165.366	173.323	EPSD	COSMIC	155.919	Up-regulation
CAMK_CAMKL_MELK_MELK_ST	P23588	EIF4B	Q14680	MELK	S311	R304K	304	Missense	distal	-7	no	165.366	149.265	EPSD	COSMIC	155.919	Loss
CAMK_CAMKL_MELK_MELK_ST	P23588	EIF4B	Q14680	MELK	S406	E402K	402	Missense	distal	-4	no	239.515	239.493	PhosphoSitePlus;EPSD	COSMIC	155.919	Down-regulation
CAMK_CAMKL_MELK_MELK_ST	P23588	EIF4B	Q14680	MELK	S422	R419K	419	Missense	distal	-3	no	213.941	231.163	EPSD;PhosphoSitePlus	COSMIC	155.919	Up-regulation
CAMK_CAMKL_MELK_MELK_ST	P23588	EIF4B	Q14680	MELK	S422	S418T	418	Missense	distal	-4	no	213.941	212.235	EPSD;PhosphoSitePlus	COSMIC	155.919	Down-regulation
CAMK_CAMKL_MELK_MELK_ST	P23588	EIF4B	Q14680	MELK	S422	R417Q	417	Missense	distal	-5	no	213.941	213.624	EPSD;PhosphoSitePlus	COSMIC	155.919	Down-regulation
CAMK_CAMKL_MELK_MELK_ST	P23588	EIF4B	Q14680	MELK	S422	G428E	428	Missense	distal	6	no	213.941	215.071	EPSD;PhosphoSitePlus	COSMIC;GDSC;CCLE	155.919	Up-regulation
CAMK_CAMKL_MELK_MELK_ST	P23588	EIF4B	Q14680	MELK	S424	R419K	419	Missense	distal	-5	no	172.050	169.053	EPSD	COSMIC	155.919	Down-regulation
CAMK_CAMKL_MELK_MELK_ST	P23588	EIF4B	Q14680	MELK	S424	S418T	418	Missense	distal	-6	no	172.050	172.561	EPSD	COSMIC	155.919	Up-regulation
CAMK_CAMKL_MELK_MELK_ST	P23588	EIF4B	Q14680	MELK	S424	R417Q	417	Missense	distal	-7	no	172.050	166.926	EPSD	COSMIC	155.919	Down-regulation
CAMK_CAMKL_MELK_MELK_ST	P23588	EIF4B	Q14680	MELK	S424	G428E	428	Missense	distal	4	no	172.050	173.315	EPSD	COSMIC;GDSC;CCLE	155.919	Up-regulation
CAMK_CAMKL_MELK_MELK_ST	P23588	EIF4B	Q14680	MELK	S425	R419K	419	Missense	distal	-6	no	156.091	150.944	EPSD	COSMIC	155.919	Loss
CAMK_CAMKL_MELK_MELK_ST	P23588	EIF4B	Q14680	MELK	S425	S418T	418	Missense	distal	-7	no	156.091	167.499	EPSD	COSMIC	155.919	Up-regulation
CAMK_CAMKL_MELK_MELK_ST	P23588	EIF4B	Q14680	MELK	S425	G428E	428	Missense	distal	3	no	156.091	149.115	EPSD	COSMIC;GDSC;CCLE	155.919	Loss
CAMK_CAMKL_MELK_MELK_ST	P23588	EIF4B	Q14680	MELK	T429	G428E	428	Missense	proximal	-1	no	165.245	159.184	EPSD	COSMIC;GDSC;CCLE	155.919	Down-regulation
CAMK_CAMKL_MELK_MELK_ST	P23588	EIF4B	Q14680	MELK	S442	E441K	441	Missense	proximal	-1	no	161.394	152.119	EPSD	COSMIC	155.919	Loss
CAMK_CAMKL_MELK_MELK_ST	P23588	EIF4B	Q14680	MELK	S544	S543I	543	Missense	proximal	-1	no	133.194	156.312	EPSD	COSMIC	155.919	Gain
CAMK_CAMKL_MELK_MELK_ST	P23588	EIF4B	Q14680	MELK	S589	Y593C	593	Missense	distal	4	no	234.017	233.106	EPSD	COSMIC	155.919	Down-regulation
STE_STE7_MEK1_MAP2K1_ST	Q13148	TARDBP	Q02750	MAP2K1	S254	L248S	248	Missense	distal	-6	no	69.759	70.028	EPSD	COSMIC	68.590	Up-regulation
STE_STE7_MEK1_MAP2K1_ST	Q13148	TARDBP	Q02750	MAP2K1	S254	S258Y	258	Missense	distal	4	no	69.759	73.178	EPSD	COSMIC	68.590	Up-regulation
STE_STE7_MEK1_MAP2K1_ST	Q13148	TARDBP	Q02750	MAP2K1	S369	N364K	364	Missense	distal	-5	no	74.908	74.349	EPSD	COSMIC	68.590	Down-regulation
STE_STE7_MEK1_MAP2K1_ST	Q13148	TARDBP	Q02750	MAP2K1	S369	G368C	368	Missense	proximal	-1	no	74.908	75.061	EPSD	COSMIC	68.590	Up-regulation
STE_STE7_MEK1_MAP2K1_ST	Q13148	TARDBP	Q02750	MAP2K1	S369	E362V	362	Missense	distal	-7	no	74.908	77.034	EPSD	COSMIC	68.590	Up-regulation
STE_STE7_MEK1_MAP2K1_ST	Q13148	TARDBP	Q02750	MAP2K1	S375	G368C	368	Missense	distal	-7	no	80.790	81.850	EPSD	COSMIC	68.590	Up-regulation
STE_STE7_MEK1_MAP2K1_ST	P28482	MAPK1	Q02750	MAP2K1	T185	F183S	183	Missense	proximal	-2	no	151.746	151.268	PhosphoSitePlus;EPSD	COSMIC	68.590	Down-regulation
STE_STE7_MEK1_MAP2K1_ST	P28482	MAPK1	Q02750	MAP2K1	T190	F183S	183	Missense	distal	-7	no	118.072	118.096	EPSD	COSMIC	68.590	Up-regulation
STE_STE7_MEK1_MAP2K1_ST	P27361	MAPK3	Q02750	MAP2K1	T202	G199D	199	Missense	distal	-3	no	153.714	150.823	EPSD;PhosphoSitePlus	COSMIC	68.590	Down-regulation
STE_STE7_MEK1_MAP2K1_ST	P27361	MAPK3	Q02750	MAP2K1	T202	T202M	202	Missense	central	0	yes	153.714	0.000	EPSD;PhosphoSitePlus	COSMIC	68.590	Loss
STE_STE7_MEK1_MAP2K1_ST	P27361	MAPK3	Q02750	MAP2K1	T202	Y204C	204	Missense	proximal	2	no	153.714	154.748	EPSD;PhosphoSitePlus	COSMIC	68.590	Up-regulation
STE_STE7_MEK1_MAP2K1_ST	P27361	MAPK3	Q02750	MAP2K1	T202	L201P	201	Missense	proximal	-1	no	153.714	128.210	EPSD;PhosphoSitePlus	COSMIC	68.590	Down-regulation
STE_STE7_MEK1_MAP2K1_ST	P27361	MAPK3	Q02750	MAP2K1	T207	R211Q	211	Missense	distal	4	no	117.682	114.177	EPSD;PhosphoSitePlus	COSMIC	68.590	Down-regulation
STE_STE7_MEK1_MAP2K1_ST	P27361	MAPK3	Q02750	MAP2K1	T207	R211P	211	Missense	distal	4	no	117.682	116.420	EPSD;PhosphoSitePlus	COSMIC	68.590	Down-regulation
STE_STE7_MEK1_MAP2K1_ST	P27361	MAPK3	Q02750	MAP2K1	T207	T202M	202	Missense	distal	-5	no	117.682	117.226	EPSD;PhosphoSitePlus	COSMIC	68.590	Down-regulation
STE_STE7_MEK1_MAP2K1_ST	P27361	MAPK3	Q02750	MAP2K1	T207	Y204C	204	Missense	distal	-3	no	117.682	114.366	EPSD;PhosphoSitePlus	COSMIC	68.590	Down-regulation
STE_STE7_MEK1_MAP2K1_ST	P27361	MAPK3	Q02750	MAP2K1	T207	L201P	201	Missense	distal	-6	no	117.682	118.112	EPSD;PhosphoSitePlus	COSMIC	68.590	Up-regulation
STE_STE7_MEK1_MAP2K1_ST	P49841	GSK3B	Q02750	MAP2K1	S25	D31Y	31	Missense	distal	6	no	84.801	86.122	EPSD	COSMIC	68.590	Up-regulation
STE_STE7_MEK1_MAP2K1_ST	P49841	GSK3B	Q02750	MAP2K1	S25	S25C	25	Missense	central	0	yes	84.801	0.000	EPSD	COSMIC	68.590	Loss
STE_STE7_MEK1_MAP2K1_ST	P49841	GSK3B	Q02750	MAP2K1	S25	A22T	22	Missense	distal	-3	no	84.801	84.423	EPSD	COSMIC	68.590	Down-regulation
STE_STE7_MEK1_MAP2K1_ST	P49841	GSK3B	Q02750	MAP2K1	T395	P391L	391	Missense	distal	-4	no	73.336	67.741	EPSD	COSMIC	68.590	Loss
STE_STE7_MEK1_MAP2K1_ST	P49841	GSK3B	Q02750	MAP2K1	T395	A397V	397	Missense	proximal	2	no	73.336	73.202	EPSD	COSMIC;CCLE	68.590	Down-regulation
STE_STE7_MEK1_MAP2K1_ST	P49841	GSK3B	Q02750	MAP2K1	T395	T402I	402	Missense	distal	7	no	73.336	73.128	EPSD	COSMIC	68.590	Down-regulation
STE_STE7_MEK1_MAP2K1_ST	P49841	GSK3B	Q02750	MAP2K1	T402	R405S	405	Missense	distal	3	no	77.413	80.154	EPSD	COSMIC	68.590	Up-regulation
STE_STE7_MEK1_MAP2K1_ST	P49841	GSK3B	Q02750	MAP2K1	T402	A397V	397	Missense	distal	-5	no	77.413	77.009	EPSD	COSMIC;CCLE	68.590	Down-regulation
STE_STE7_MEK1_MAP2K1_ST	P49841	GSK3B	Q02750	MAP2K1	T402	T402I	402	Missense	central	0	yes	77.413	0.000	EPSD	COSMIC	68.590	Loss
STE_STE7_MEK1_MAP2K1_ST	P49841	GSK3B	Q02750	MAP2K1	T402	R405H	405	Missense	distal	3	no	77.413	79.375	EPSD	COSMIC;CCLE	68.590	Up-regulation
STE_STE7_MEK1_MAP2K1_ST	P05787	KRT8	Q02750	MAP2K1	T6	S9F	9	Missense	distal	3	no	81.339	83.633	EPSD	COSMIC	68.590	Up-regulation
STE_STE7_MEK1_MAP2K1_ST	P05787	KRT8	Q02750	MAP2K1	S9	S9F	9	Missense	central	0	yes	76.274	0.000	EPSD	COSMIC	68.590	Loss
STE_STE7_MEK1_MAP2K1_ST	P05787	KRT8	Q02750	MAP2K1	S37	S43F	43	Missense	distal	6	no	69.115	68.893	EPSD	COSMIC	68.590	Down-regulation
STE_STE7_MEK1_MAP2K1_ST	P05787	KRT8	Q02750	MAP2K1	S37	S31A	31	Missense	distal	-6	no	69.115	69.188	EPSD	COSMIC	68.590	Up-regulation
STE_STE7_MEK1_MAP2K1_ST	P05787	KRT8	Q02750	MAP2K1	S37	S36L	36	Missense	proximal	-1	no	69.115	77.815	EPSD	COSMIC	68.590	Up-regulation
STE_STE7_MEK1_MAP2K1_ST	P05787	KRT8	Q02750	MAP2K1	S37	S43I	43	Missense	distal	6	no	69.115	68.662	EPSD	COSMIC	68.590	Down-regulation
STE_STE7_MEK1_MAP2K1_ST	P05787	KRT8	Q02750	MAP2K1	S37	S43R	43	Missense	distal	6	no	69.115	70.667	EPSD	COSMIC	68.590	Up-regulation
STE_STE7_MEK1_MAP2K1_ST	P05787	KRT8	Q02750	MAP2K1	S37	S31Y	31	Missense	distal	-6	no	69.115	68.752	EPSD	COSMIC	68.590	Down-regulation
STE_STE7_MEK1_MAP2K1_ST	P05787	KRT8	Q02750	MAP2K1	S37	S35F	35	Missense	proximal	-2	no	69.115	69.594	EPSD	COSMIC	68.590	Up-regulation
STE_STE7_MEK1_MAP2K1_ST	P05787	KRT8	Q02750	MAP2K1	S74	S71R	71	Missense	distal	-3	no	140.764	144.426	PhosphoSitePlus	COSMIC	68.590	Up-regulation
STE_STE7_MEK1_MAP2K1_ST	P05787	KRT8	Q02750	MAP2K1	S74	S71I	71	Missense	distal	-3	no	140.764	141.374	PhosphoSitePlus	COSMIC	68.590	Up-regulation
STE_STE7_MEK1_MAP2K1_ST	P05787	KRT8	Q02750	MAP2K1	S74	V77G	77	Missense	distal	3	no	140.764	138.127	PhosphoSitePlus	COSMIC	68.590	Down-regulation
STE_STE7_MEK1_MAP2K1_ST	P05787	KRT8	Q02750	MAP2K1	T242	D241E	241	Missense	proximal	-1	no	88.826	76.313	EPSD	COSMIC	68.590	Down-regulation
STE_STE7_MEK1_MAP2K1_ST	Q00613	HSF1	Q02750	MAP2K1	S237	G236S	236	Missense	proximal	-1	no	81.356	86.542	EPSD	COSMIC;CCLE	68.590	Up-regulation
STE_STE7_MEK1_MAP2K1_ST	Q00613	HSF1	Q02750	MAP2K1	S237	S237L	237	Missense	central	0	yes	81.356	0.000	EPSD	COSMIC	68.590	Loss
STE_STE7_MEK1_MAP2K1_ST	Q00613	HSF1	Q02750	MAP2K1	S237	P239H	239	Missense	proximal	2	no	81.356	82.389	EPSD	COSMIC	68.590	Up-regulation
STE_STE7_MEK1_MAP2K1_ST	Q00613	HSF1	Q02750	MAP2K1	S237	S244F	244	Missense	distal	7	no	81.356	81.330	EPSD	COSMIC	68.590	Down-regulation
STE_STE7_MEK1_MAP2K1_ST	Q00613	HSF1	Q02750	MAP2K1	S290	R287K	287	Missense	distal	-3	no	70.764	70.519	EPSD	COSMIC	68.590	Down-regulation
STE_STE7_MEK1_MAP2K1_ST	Q00613	HSF1	Q02750	MAP2K1	S290	S283N	283	Missense	distal	-7	no	70.764	69.632	EPSD	COSMIC	68.590	Down-regulation
STE_STE7_MEK1_MAP2K1_ST	Q00613	HSF1	Q02750	MAP2K1	S291	R287K	287	Missense	distal	-4	no	77.443	79.434	EPSD	COSMIC	68.590	Up-regulation
STE_STE7_MEK1_MAP2K1_ST	Q00613	HSF1	Q02750	MAP2K1	S292	R287K	287	Missense	distal	-5	no	86.996	87.177	EPSD	COSMIC	68.590	Up-regulation
STE_STE7_MEK1_MAP2K1_ST	Q00613	HSF1	Q02750	MAP2K1	S314	R309G	309	Missense	distal	-5	no	68.744	69.908	EPSD	COSMIC	68.590	Up-regulation
STE_STE7_MEK1_MAP2K1_ST	Q00613	HSF1	Q02750	MAP2K1	S314	P318T	318	Missense	distal	4	no	68.744	66.213	EPSD	COSMIC	68.590	Loss
STE_STE7_MEK1_MAP2K1_ST	Q00613	HSF1	Q02750	MAP2K1	S319	P318T	318	Missense	proximal	-1	no	57.597	78.877	EPSD	COSMIC	68.590	Gain
STE_STE7_MEK1_MAP2K1_ST	Q00613	HSF1	Q02750	MAP2K1	S326	L330V	330	Missense	distal	4	no	134.037	134.653	PhosphoSitePlus	COSMIC	68.590	Up-regulation
STE_STE7_MEK1_MAP2K1_ST	Q00613	HSF1	Q02750	MAP2K1	S326	P327Q	327	Missense	proximal	1	no	134.037	127.743	PhosphoSitePlus	COSMIC	68.590	Down-regulation
STE_STE7_MEK1_MAP2K1_ST	Q00613	HSF1	Q02750	MAP2K1	S338	P342T	342	Missense	distal	4	no	77.009	74.477	EPSD	COSMIC	68.590	Down-regulation
STE_STE7_MEK1_MAP2K1_ST	Q00613	HSF1	Q02750	MAP2K1	S338	S344C	344	Missense	distal	6	no	77.009	76.580	EPSD	COSMIC	68.590	Down-regulation
STE_STE7_MEK1_MAP2K1_ST	Q00613	HSF1	Q02750	MAP2K1	S338	R336W	336	Missense	proximal	-2	no	77.009	71.710	EPSD	COSMIC	68.590	Down-regulation
STE_STE7_MEK1_MAP2K1_ST	P04049	RAF1	Q02750	MAP2K1	S243	A237T	237	Missense	distal	-6	no	68.679	68.568	EPSD	COSMIC;CCLE	68.590	Loss
STE_STE7_MEK1_MAP2K1_ST	P04049	RAF1	Q02750	MAP2K1	S243	S244R	244	Missense	proximal	1	no	68.679	64.229	EPSD	COSMIC	68.590	Loss
STE_STE7_MEK1_MAP2K1_ST	P04049	RAF1	Q02750	MAP2K1	S259	S259A	259	Missense	central	0	yes	86.342	0.000	EPSD	COSMIC	68.590	Loss
STE_STE7_MEK1_MAP2K1_ST	P04049	RAF1	Q02750	MAP2K1	S259	P261L	261	Missense	proximal	2	no	86.342	87.882	EPSD	COSMIC	68.590	Up-regulation
STE_STE7_MEK1_MAP2K1_ST	P04049	RAF1	Q02750	MAP2K1	S259	S259C	259	Missense	central	0	yes	86.342	0.000	EPSD	COSMIC	68.590	Loss
STE_STE7_MEK1_MAP2K1_ST	P04049	RAF1	Q02750	MAP2K1	S259	S259P	259	Missense	central	0	yes	86.342	0.000	EPSD	COSMIC	68.590	Loss
STE_STE7_MEK1_MAP2K1_ST	P04049	RAF1	Q02750	MAP2K1	S259	T260K	260	Missense	proximal	1	no	86.342	93.568	EPSD	COSMIC	68.590	Up-regulation
STE_STE7_MEK1_MAP2K1_ST	P04049	RAF1	Q02750	MAP2K1	S259	P261T	261	Missense	proximal	2	no	86.342	88.506	EPSD	COSMIC	68.590	Up-regulation
STE_STE7_MEK1_MAP2K1_ST	P04049	RAF1	Q02750	MAP2K1	S259	N262K	262	Missense	distal	3	no	86.342	86.911	EPSD	COSMIC	68.590	Up-regulation
STE_STE7_MEK1_MAP2K1_ST	P04049	RAF1	Q02750	MAP2K1	S259	T260I	260	Missense	proximal	1	no	86.342	93.207	EPSD	COSMIC	68.590	Up-regulation
STE_STE7_MEK1_MAP2K1_ST	P04049	RAF1	Q02750	MAP2K1	S259	P261S	261	Missense	proximal	2	no	86.342	88.732	EPSD	COSMIC	68.590	Up-regulation
STE_STE7_MEK1_MAP2K1_ST	P04049	RAF1	Q02750	MAP2K1	S259	V263A	263	Missense	distal	4	no	86.342	84.683	EPSD	COSMIC	68.590	Down-regulation
STE_STE7_MEK1_MAP2K1_ST	P04049	RAF1	Q02750	MAP2K1	S259	V263D	263	Missense	distal	4	no	86.342	85.816	EPSD	COSMIC	68.590	Down-regulation
STE_STE7_MEK1_MAP2K1_ST	P04049	RAF1	Q02750	MAP2K1	T268	P261L	261	Missense	distal	-7	no	68.866	71.712	EPSD	COSMIC	68.590	Up-regulation
STE_STE7_MEK1_MAP2K1_ST	P04049	RAF1	Q02750	MAP2K1	T268	D273Y	273	Missense	distal	5	no	68.866	69.810	EPSD	COSMIC	68.590	Up-regulation
STE_STE7_MEK1_MAP2K1_ST	P04049	RAF1	Q02750	MAP2K1	T268	P261T	261	Missense	distal	-7	no	68.866	69.378	EPSD	COSMIC	68.590	Up-regulation
STE_STE7_MEK1_MAP2K1_ST	P04049	RAF1	Q02750	MAP2K1	T268	N262K	262	Missense	distal	-6	no	68.866	68.303	EPSD	COSMIC	68.590	Loss
STE_STE7_MEK1_MAP2K1_ST	P04049	RAF1	Q02750	MAP2K1	T268	P261S	261	Missense	distal	-7	no	68.866	69.481	EPSD	COSMIC	68.590	Up-regulation
STE_STE7_MEK1_MAP2K1_ST	P04049	RAF1	Q02750	MAP2K1	T268	V263A	263	Missense	distal	-5	no	68.866	69.270	EPSD	COSMIC	68.590	Up-regulation
STE_STE7_MEK1_MAP2K1_ST	P04049	RAF1	Q02750	MAP2K1	T268	V263D	263	Missense	distal	-5	no	68.866	69.428	EPSD	COSMIC	68.590	Up-regulation
STE_STE7_MEK1_MAP2K1_ST	P04049	RAF1	Q02750	MAP2K1	S338	R333C	333	Missense	distal	-5	no	137.395	138.172	PhosphoSitePlus	COSMIC	68.590	Up-regulation
STE_STE7_MEK1_MAP2K1_ST	P04049	RAF1	Q02750	MAP2K1	S338	Q335H	335	Missense	distal	-3	no	137.395	137.498	PhosphoSitePlus	COSMIC;GDSC;CCLE	68.590	Up-regulation
STE_STE7_MEK1_MAP2K1_ST	P04049	RAF1	Q02750	MAP2K1	S642	P643S	643	Missense	proximal	1	no	99.481	95.889	EPSD	COSMIC	68.590	Down-regulation
AGC_GRK_GRK_GRK4_ST	P32298	GRK4	P32298	GRK4	S10	V7M	7	Missense	distal	-3	no	15.694	15.642	EPSD;PhosphoSitePlus	COSMIC	10.085	Down-regulation
AGC_GRK_GRK_GRK4_ST	P32298	GRK4	P32298	GRK4	S10	L12P	12	Missense	proximal	2	no	15.694	16.368	EPSD;PhosphoSitePlus	COSMIC	10.085	Up-regulation
AGC_GRK_GRK_GRK4_ST	P32298	GRK4	P32298	GRK4	S139	K134E	134	Missense	distal	-5	no	17.260	17.277	EPSD;PhosphoSitePlus	COSMIC	10.085	Up-regulation
AGC_GRK_GRK_GRK4_ST	P32298	GRK4	P32298	GRK4	S139	K134Q	134	Missense	distal	-5	no	17.260	17.247	EPSD;PhosphoSitePlus	COSMIC	10.085	Down-regulation
AGC_GRK_GRK_GRK4_ST	P32298	GRK4	P32298	GRK4	S139	S139F	139	Missense	central	0	yes	17.260	0.000	EPSD;PhosphoSitePlus	COSMIC	10.085	Loss
AGC_GRK_GRK_GRK4_ST	P32298	GRK4	P32298	GRK4	S244	V247I	247	Missense	distal	3	no	17.613	17.382	EPSD;PhosphoSitePlus	COSMIC	10.085	Down-regulation
AGC_GRK_GRK_GRK4_ST	P32298	GRK4	P32298	GRK4	S244	I238F	238	Missense	distal	-6	no	17.613	16.279	EPSD;PhosphoSitePlus	COSMIC	10.085	Down-regulation
AGC_GRK_GRK_GRK4_ST	P32298	GRK4	P32298	GRK4	S244	V248D	248	Missense	distal	4	no	17.613	17.732	EPSD;PhosphoSitePlus	COSMIC	10.085	Up-regulation
AGC_GRK_GRK_GRK4_ST	P32298	GRK4	P32298	GRK4	S249	V247I	247	Missense	proximal	-2	no	21.200	21.202	EPSD;PhosphoSitePlus	COSMIC	10.085	Up-regulation
AGC_GRK_GRK_GRK4_ST	P32298	GRK4	P32298	GRK4	S249	V248D	248	Missense	proximal	-1	no	21.200	21.181	EPSD;PhosphoSitePlus	COSMIC	10.085	Down-regulation
AGC_GRK_GRK_GRK4_ST	P32298	GRK4	P32298	GRK4	T256	L262F	262	Missense	distal	6	no	17.867	16.797	EPSD;PhosphoSitePlus	COSMIC	10.085	Down-regulation
AGC_GRK_GRK_GRK4_ST	P32298	GRK4	P32298	GRK4	T256	K257E	257	Missense	proximal	1	no	17.867	16.788	EPSD;PhosphoSitePlus	COSMIC	10.085	Down-regulation
AGC_GRK_GRK_GRK4_ST	P32298	GRK4	P32298	GRK4	S419	S414L	414	Missense	distal	-5	no	18.904	18.822	PhosphoSitePlus;EPSD	COSMIC	10.085	Down-regulation
AGC_GRK_GRK_GRK4_ST	P32298	GRK4	P32298	GRK4	T426	N428K	428	Missense	proximal	2	no	17.615	16.476	EPSD;PhosphoSitePlus	COSMIC	10.085	Down-regulation
AGC_GRK_GRK_GRK4_ST	P32298	GRK4	P32298	GRK4	S430	G434C	434	Missense	distal	4	no	17.962	17.931	EPSD;PhosphoSitePlus	COSMIC	10.085	Down-regulation
AGC_GRK_GRK_GRK4_ST	P32298	GRK4	P32298	GRK4	S430	N428K	428	Missense	proximal	-2	no	17.962	17.953	EPSD;PhosphoSitePlus	COSMIC	10.085	Down-regulation
AGC_GRK_GRK_GRK4_ST	P32298	GRK4	P32298	GRK4	S485	I490T	490	Missense	distal	5	no	19.229	19.079	EPSD;PhosphoSitePlus	COSMIC	10.085	Down-regulation
AGC_GRK_GRK_GRK4_ST	P30411	BDKRB2	P32298	GRK4	S366	P360H	360	Missense	distal	-6	no	17.238	16.555	PhosphoSitePlus;EPSD	COSMIC	10.085	Down-regulation
AGC_GRK_GRK_GRK4_ST	P30411	BDKRB2	P32298	GRK4	S366	P360L	360	Missense	distal	-6	no	17.238	18.591	PhosphoSitePlus;EPSD	COSMIC;CCLE	10.085	Up-regulation
AGC_GRK_GRK_GRK4_ST	P30411	BDKRB2	P32298	GRK4	S366	R371Q	371	Missense	distal	5	no	17.238	17.500	PhosphoSitePlus;EPSD	COSMIC	10.085	Up-regulation
AGC_GRK_GRK_GRK4_ST	P30411	BDKRB2	P32298	GRK4	S373	Q379H	379	Missense	distal	6	no	15.602	15.583	EPSD;PhosphoSitePlus	COSMIC	10.085	Down-regulation
AGC_GRK_GRK_GRK4_ST	P30411	BDKRB2	P32298	GRK4	S373	R371Q	371	Missense	proximal	-2	no	15.602	15.607	EPSD;PhosphoSitePlus	COSMIC	10.085	Up-regulation
AGC_GRK_GRK_GRK4_ST	P30411	BDKRB2	P32298	GRK4	S375	Q379H	379	Missense	distal	4	no	14.245	14.288	EPSD;PhosphoSitePlus	COSMIC	10.085	Up-regulation
AGC_GRK_GRK_GRK4_ST	P30411	BDKRB2	P32298	GRK4	S375	R371Q	371	Missense	distal	-4	no	14.245	13.098	EPSD;PhosphoSitePlus	COSMIC	10.085	Down-regulation
CAMK_CAMKL_QIK_SIK2_ST	P27986	PIK3R1	Q9H0K1	SIK2	S43	L37R	37	Missense	distal	-6	no	1.583	1.520	EPSD	COSMIC	1.318	Down-regulation
CAMK_CAMKL_QIK_SIK2_ST	P27986	PIK3R1	Q9H0K1	SIK2	S43	S36N	36	Missense	distal	-7	no	1.583	1.533	EPSD	COSMIC	1.318	Down-regulation
CAMK_CAMKL_QIK_SIK2_ST	P27986	PIK3R1	Q9H0K1	SIK2	S154	L149I	149	Missense	distal	-5	no	2.370	2.284	PhosphoSitePlus;EPSD	COSMIC	1.318	Down-regulation
CAMK_CAMKL_QIK_SIK2_ST	P27986	PIK3R1	Q9H0K1	SIK2	S154	L149S	149	Missense	distal	-5	no	2.370	2.209	PhosphoSitePlus;EPSD	COSMIC	1.318	Down-regulation
CAMK_CAMKL_QIK_SIK2_ST	P27986	PIK3R1	Q9H0K1	SIK2	S154	T148I	148	Missense	distal	-6	no	2.370	2.382	PhosphoSitePlus;EPSD	COSMIC	1.318	Up-regulation
CAMK_CAMKL_QIK_SIK2_ST	P27986	PIK3R1	Q9H0K1	SIK2	S154	N157H	157	Missense	distal	3	no	2.370	2.358	PhosphoSitePlus;EPSD	COSMIC	1.318	Down-regulation
CAMK_CAMKL_QIK_SIK2_ST	P27986	PIK3R1	Q9H0K1	SIK2	S156	L149I	149	Missense	distal	-7	no	1.570	1.563	EPSD	COSMIC	1.318	Down-regulation
CAMK_CAMKL_QIK_SIK2_ST	P27986	PIK3R1	Q9H0K1	SIK2	S156	L149S	149	Missense	distal	-7	no	1.570	1.617	EPSD	COSMIC	1.318	Up-regulation
CAMK_CAMKL_QIK_SIK2_ST	P27986	PIK3R1	Q9H0K1	SIK2	S156	R162Q	162	Missense	distal	6	no	1.570	1.649	EPSD	COSMIC	1.318	Up-regulation
CAMK_CAMKL_QIK_SIK2_ST	P27986	PIK3R1	Q9H0K1	SIK2	S156	N157H	157	Missense	proximal	1	no	1.570	1.568	EPSD	COSMIC	1.318	Down-regulation
CAMK_CAMKL_QIK_SIK2_ST	P27986	PIK3R1	Q9H0K1	SIK2	S208	V213I	213	Missense	distal	5	no	1.448	1.370	EPSD	COSMIC	1.318	Down-regulation
CAMK_CAMKL_QIK_SIK2_ST	P27986	PIK3R1	Q9H0K1	SIK2	S208	Y203C	203	Missense	distal	-5	no	1.448	1.488	EPSD	COSMIC	1.318	Up-regulation
CAMK_CAMKL_QIK_SIK2_ST	P27986	PIK3R1	Q9H0K1	SIK2	S208	L209F	209	Missense	proximal	1	no	1.448	1.450	EPSD	COSMIC	1.318	Up-regulation
CAMK_CAMKL_QIK_SIK2_ST	P27986	PIK3R1	Q9H0K1	SIK2	S208	E205K	205	Missense	distal	-3	no	1.448	1.482	EPSD	COSMIC	1.318	Up-regulation
CAMK_CAMKL_QIK_SIK2_ST	P27986	PIK3R1	Q9H0K1	SIK2	S208	E212K	212	Missense	distal	4	no	1.448	1.277	EPSD	COSMIC	1.318	Loss
CAMK_CAMKL_QIK_SIK2_ST	P27986	PIK3R1	Q9H0K1	SIK2	S208	A210D	210	Missense	proximal	2	no	1.448	1.443	EPSD	COSMIC	1.318	Down-regulation
CAMK_CAMKL_QIK_SIK2_ST	P27986	PIK3R1	Q9H0K1	SIK2	S208	Q214L	214	Missense	distal	6	no	1.448	1.228	EPSD	COSMIC	1.318	Loss
CAMK_CAMKL_QIK_SIK2_ST	P27986	PIK3R1	Q9H0K1	SIK2	S279	T283I	283	Missense	distal	4	no	1.180	1.340	EPSD	COSMIC	1.318	Gain
CAMK_CAMKL_QIK_SIK2_ST	P27986	PIK3R1	Q9H0K1	SIK2	S280	R274K	274	Missense	distal	-6	no	1.300	1.386	EPSD	COSMIC	1.318	Gain
CAMK_CAMKL_QIK_SIK2_ST	P27986	PIK3R1	Q9H0K1	SIK2	S280	R274T	274	Missense	distal	-6	no	1.300	1.371	EPSD	COSMIC	1.318	Gain
CAMK_CAMKL_QIK_SIK2_ST	P27986	PIK3R1	Q9H0K1	SIK2	S280	R274G	274	Missense	distal	-6	no	1.300	1.406	EPSD	COSMIC	1.318	Gain
CAMK_CAMKL_QIK_SIK2_ST	P27986	PIK3R1	Q9H0K1	SIK2	S280	R274I	274	Missense	distal	-6	no	1.300	1.383	EPSD	COSMIC	1.318	Gain
CAMK_CAMKL_QIK_SIK2_ST	P27986	PIK3R1	Q9H0K1	SIK2	S280	N285H	285	Missense	distal	5	no	1.300	1.378	EPSD	COSMIC	1.318	Gain
CAMK_CAMKL_QIK_SIK2_ST	P27986	PIK3R1	Q9H0K1	SIK2	S541	D548G	548	Missense	distal	7	no	2.328	2.273	EPSD;PhosphoSitePlus	COSMIC	1.318	Down-regulation
CAMK_CAMKL_QIK_SIK2_ST	P27986	PIK3R1	Q9H0K1	SIK2	S541	I535F	535	Missense	distal	-6	no	2.328	2.306	EPSD;PhosphoSitePlus	COSMIC	1.318	Down-regulation
CAMK_CAMKL_QIK_SIK2_ST	P27986	PIK3R1	Q9H0K1	SIK2	S541	R543I	543	Missense	proximal	2	no	2.328	2.316	EPSD;PhosphoSitePlus	COSMIC	1.318	Down-regulation
CAMK_CAMKL_QIK_SIK2_ST	P27986	PIK3R1	Q9H0K1	SIK2	S541	R544K	544	Missense	distal	3	no	2.328	2.253	EPSD;PhosphoSitePlus	COSMIC	1.318	Down-regulation
CAMK_CAMKL_QIK_SIK2_ST	P27986	PIK3R1	Q9H0K1	SIK2	S608	D615Y	615	Missense	distal	7	no	1.602	1.573	EPSD	COSMIC	1.318	Down-regulation
CAMK_CAMKL_QIK_SIK2_ST	P27986	PIK3R1	Q9H0K1	SIK2	S608	Q606H	606	Missense	proximal	-2	no	1.602	1.565	EPSD	COSMIC	1.318	Down-regulation
CAMK_CAMKL_QIK_SIK2_ST	P27986	PIK3R1	Q9H0K1	SIK2	S608	E614K	614	Missense	distal	6	no	1.602	1.556	EPSD	COSMIC	1.318	Down-regulation
CAMK_CAMKL_QIK_SIK2_ST	P27986	PIK3R1	Q9H0K1	SIK2	S608	E611K	611	Missense	distal	3	no	1.602	1.580	EPSD	COSMIC	1.318	Down-regulation
CAMK_CAMKL_QIK_SIK2_ST	P27986	PIK3R1	Q9H0K1	SIK2	S608	E601K	601	Missense	distal	-7	no	1.602	1.604	EPSD	COSMIC	1.318	Up-regulation
CAMK_CAMKL_QIK_SIK2_ST	Q9H0K1	SIK2	Q9H0K1	SIK2	S90	T96I	96	Missense	distal	6	no	2.301	2.013	PhosphoSitePlus;EPSD	COSMIC	1.318	Down-regulation
CAMK_CAMKL_QIK_SIK2_ST	Q9H0K1	SIK2	Q9H0K1	SIK2	S90	V95E	95	Missense	distal	5	no	2.301	2.287	PhosphoSitePlus;EPSD	COSMIC	1.318	Down-regulation
CAMK_CAMKL_QIK_SIK2_ST	Q9H0K1	SIK2	Q9H0K1	SIK2	S90	Y93C	93	Missense	distal	3	no	2.301	2.214	PhosphoSitePlus;EPSD	COSMIC	1.318	Down-regulation
CAMK_CAMKL_QIK_SIK2_ST	Q9H0K1	SIK2	Q9H0K1	SIK2	S90	E97K	97	Missense	distal	7	no	2.301	2.266	PhosphoSitePlus;EPSD	COSMIC	1.318	Down-regulation
CAMK_CAMKL_QIK_SIK2_ST	Q9H0K1	SIK2	Q9H0K1	SIK2	S486	L485M	485	Missense	proximal	-1	no	1.429	1.421	EPSD	COSMIC	1.318	Down-regulation
CAMK_CAMKL_QIK_SIK2_ST	Q9H0K1	SIK2	Q9H0K1	SIK2	S486	Q491K	491	Missense	distal	5	no	1.429	1.422	EPSD	COSMIC	1.318	Down-regulation
CAMK_CAMKL_QIK_SIK2_ST	Q9H0K1	SIK2	Q9H0K1	SIK2	S486	L485V	485	Missense	proximal	-1	no	1.429	1.393	EPSD	COSMIC	1.318	Down-regulation
CAMK_CAMKL_QIK_SIK2_ST	Q9H0K1	SIK2	Q9H0K1	SIK2	S512	Y517F	517	Missense	distal	5	no	1.363	1.316	EPSD	COSMIC	1.318	Loss
CAMK_CAMKL_QIK_SIK2_ST	Q9H0K1	SIK2	Q9H0K1	SIK2	S512	D506A	506	Missense	distal	-6	no	1.363	1.304	EPSD	COSMIC;CCLE	1.318	Loss
CAMK_CAMKL_QIK_SIK2_ST	Q9H0K1	SIK2	Q9H0K1	SIK2	S512	L510I	510	Missense	proximal	-2	no	1.363	1.405	EPSD	COSMIC	1.318	Up-regulation
CAMK_CAMKL_QIK_SIK2_ST	Q9H0K1	SIK2	Q9H0K1	SIK2	S545	S550A	550	Missense	distal	5	no	1.465	1.492	EPSD	COSMIC	1.318	Up-regulation
CAMK_CAMKL_QIK_SIK2_ST	Q9H0K1	SIK2	Q9H0K1	SIK2	S545	R547S	547	Missense	proximal	2	no	1.465	1.481	EPSD	COSMIC	1.318	Up-regulation
CAMK_CAMKL_QIK_SIK2_ST	Q15078	CDK5R1	Q9H0K1	SIK2	S10	L7R	7	Missense	distal	-3	no	1.291	1.336	EPSD	COSMIC	1.318	Gain
CAMK_CAMKL_QIK_SIK2_ST	Q15078	CDK5R1	Q9H0K1	SIK2	S263	R260H	260	Missense	distal	-3	no	1.333	1.302	EPSD	COSMIC	1.318	Loss
CAMK_CAMKL_QIK_SIK2_ST	Q15078	CDK5R1	Q9H0K1	SIK2	S263	R260C	260	Missense	distal	-3	no	1.333	1.239	EPSD	COSMIC	1.318	Loss
CAMK_CAMKL_QIK_SIK2_ST	Q9BV73	CEP250	Q9H0K1	SIK2	S45	E47G	47	Missense	proximal	2	no	1.457	1.466	EPSD	COSMIC	1.318	Up-regulation
CAMK_CAMKL_QIK_SIK2_ST	Q9BV73	CEP250	Q9H0K1	SIK2	S45	S45F	45	Missense	central	0	yes	1.457	0.000	EPSD	COSMIC	1.318	Loss
CAMK_CAMKL_QIK_SIK2_ST	Q9BV73	CEP250	Q9H0K1	SIK2	S331	A334V	334	Missense	distal	3	no	1.454	1.374	EPSD	COSMIC	1.318	Down-regulation
CAMK_CAMKL_QIK_SIK2_ST	Q9BV73	CEP250	Q9H0K1	SIK2	S583	E584Q	584	Missense	proximal	1	no	1.382	1.380	EPSD	COSMIC	1.318	Down-regulation
CAMK_CAMKL_QIK_SIK2_ST	Q9BV73	CEP250	Q9H0K1	SIK2	S583	L587M	587	Missense	distal	4	no	1.382	1.081	EPSD	COSMIC	1.318	Loss
CAMK_CAMKL_QIK_SIK2_ST	Q9BV73	CEP250	Q9H0K1	SIK2	S1060	K1064N	1064	Missense	distal	4	no	1.658	1.637	EPSD	COSMIC;GDSC;CCLE	1.318	Down-regulation
CAMK_CAMKL_QIK_SIK2_ST	Q9BV73	CEP250	Q9H0K1	SIK2	S1060	Q1066H	1066	Missense	distal	6	no	1.658	1.472	EPSD	COSMIC	1.318	Down-regulation
CAMK_CAMKL_QIK_SIK2_ST	Q9BV73	CEP250	Q9H0K1	SIK2	S1237	P1231T	1231	Missense	distal	-6	no	1.499	1.542	EPSD	COSMIC	1.318	Up-regulation
CAMK_CAMKL_QIK_SIK2_ST	Q9BV73	CEP250	Q9H0K1	SIK2	S1237	A1238V	1238	Missense	proximal	1	no	1.499	1.497	EPSD	COSMIC	1.318	Down-regulation
CAMK_CAMKL_QIK_SIK2_ST	Q9BV73	CEP250	Q9H0K1	SIK2	S1237	S1243F	1243	Missense	distal	6	no	1.499	1.409	EPSD	COSMIC	1.318	Down-regulation
CAMK_CAMKL_QIK_SIK2_ST	Q9BV73	CEP250	Q9H0K1	SIK2	S1295	L1294H	1294	Missense	proximal	-1	no	1.387	1.419	EPSD	COSMIC	1.318	Up-regulation
CAMK_CAMKL_QIK_SIK2_ST	Q9BV73	CEP250	Q9H0K1	SIK2	S1295	Q1296L	1296	Missense	proximal	1	no	1.387	1.386	EPSD	COSMIC	1.318	Down-regulation
CAMK_CAMKL_QIK_SIK2_ST	Q9BV73	CEP250	Q9H0K1	SIK2	S1295	E1300K	1300	Missense	distal	5	no	1.387	1.373	EPSD	COSMIC	1.318	Down-regulation
CAMK_CAMKL_QIK_SIK2_ST	Q9BV73	CEP250	Q9H0K1	SIK2	S1372	G1375S	1375	Missense	distal	3	no	1.347	1.491	EPSD	COSMIC	1.318	Up-regulation
CAMK_CAMKL_QIK_SIK2_ST	Q9BV73	CEP250	Q9H0K1	SIK2	S1386	R1385C	1385	Missense	proximal	-1	no	1.304	1.347	EPSD	COSMIC	1.318	Gain
CAMK_CAMKL_QIK_SIK2_ST	Q9BV73	CEP250	Q9H0K1	SIK2	S1386	R1385P	1385	Missense	proximal	-1	no	1.304	1.330	EPSD	COSMIC	1.318	Gain
CAMK_CAMKL_QIK_SIK2_ST	Q9BV73	CEP250	Q9H0K1	SIK2	S1691	L1692S	1692	Missense	proximal	1	no	1.453	1.457	EPSD	COSMIC	1.318	Up-regulation
CAMK_CAMKL_QIK_SIK2_ST	Q9BV73	CEP250	Q9H0K1	SIK2	S1803	Q1809K	1809	Missense	distal	6	no	1.658	1.497	EPSD	COSMIC	1.318	Down-regulation
CAMK_CAMKL_QIK_SIK2_ST	Q9BV73	CEP250	Q9H0K1	SIK2	S1927	A1931V	1931	Missense	distal	4	no	1.181	1.321	EPSD	COSMIC	1.318	Gain
CAMK_CAMKL_QIK_SIK2_ST	Q9BV73	CEP250	Q9H0K1	SIK2	S2186	A2181T	2181	Missense	distal	-5	no	1.387	1.329	EPSD	COSMIC	1.318	Down-regulation
CAMK_CAMKL_QIK_SIK2_ST	Q9BV73	CEP250	Q9H0K1	SIK2	S2188	A2181T	2181	Missense	distal	-7	no	1.455	1.480	EPSD	COSMIC	1.318	Up-regulation
CAMK_CAMKL_QIK_SIK2_ST	Q9BV73	CEP250	Q9H0K1	SIK2	S2322	R2316C	2316	Missense	distal	-6	no	1.255	1.321	EPSD	COSMIC	1.318	Gain
CAMK_CAMKL_QIK_SIK2_ST	Q9BV73	CEP250	Q9H0K1	SIK2	S2390	H2388N	2388	Missense	proximal	-2	no	1.500	1.501	EPSD	COSMIC	1.318	Up-regulation
CAMK_CAMKL_QIK_SIK2_ST	Q9BV73	CEP250	Q9H0K1	SIK2	S2392	H2388N	2388	Missense	distal	-4	no	2.291	2.286	PhosphoSitePlus;EPSD	COSMIC	1.318	Down-regulation
CAMK_CAMKL_QIK_SIK2_ST	Q9BV73	CEP250	Q9H0K1	SIK2	S2392	V2398M	2398	Missense	distal	6	no	2.291	2.163	PhosphoSitePlus;EPSD	COSMIC	1.318	Down-regulation
CAMK_CAMKL_QIK_SIK2_ST	Q9BV73	CEP250	Q9H0K1	SIK2	S2394	H2388N	2388	Missense	distal	-6	no	2.292	2.283	EPSD;PhosphoSitePlus	COSMIC	1.318	Down-regulation
CAMK_CAMKL_QIK_SIK2_ST	Q9BV73	CEP250	Q9H0K1	SIK2	S2394	V2398M	2398	Missense	distal	4	no	2.292	2.082	EPSD;PhosphoSitePlus	COSMIC	1.318	Down-regulation
CAMK_CAMKL_QIK_SIK2_ST	Q9BV73	CEP250	Q9H0K1	SIK2	S2417	R2413K	2413	Missense	distal	-4	no	1.680	1.661	EPSD	COSMIC	1.318	Down-regulation
CAMK_CAMKL_QIK_SIK2_ST	Q9BV73	CEP250	Q9H0K1	SIK2	S2435	P2432L	2432	Missense	distal	-3	no	1.343	1.398	EPSD	COSMIC	1.318	Up-regulation
CAMK_CAMKL_QIK_SIK2_ST	Q9BV73	CEP250	Q9H0K1	SIK2	S2435	Q2438K	2438	Missense	distal	3	no	1.343	1.309	EPSD	COSMIC	1.318	Loss
CAMK_CAMKL_QIK_SIK2_ST	Q9UQL6	HDAC5	Q9H0K1	SIK2	S16	L20M	20	Missense	distal	4	no	1.413	1.112	EPSD	COSMIC	1.318	Loss
CAMK_CAMKL_QIK_SIK2_ST	Q9UQL6	HDAC5	Q9H0K1	SIK2	S16	R13W	13	Missense	distal	-3	no	1.413	1.366	EPSD	COSMIC	1.318	Down-regulation
CAMK_CAMKL_QIK_SIK2_ST	Q9UQL6	HDAC5	Q9H0K1	SIK2	S16	L17F	17	Missense	proximal	1	no	1.413	1.415	EPSD	COSMIC	1.318	Up-regulation
CAMK_CAMKL_QIK_SIK2_ST	Q9UQL6	HDAC5	Q9H0K1	SIK2	S16	E18Q	18	Missense	proximal	2	no	1.413	1.406	EPSD	COSMIC	1.318	Down-regulation
CAMK_CAMKL_QIK_SIK2_ST	Q9UQL6	HDAC5	Q9H0K1	SIK2	S16	G12R	12	Missense	distal	-4	no	1.413	1.490	EPSD	COSMIC	1.318	Up-regulation
CAMK_CAMKL_QIK_SIK2_ST	Q9UQL6	HDAC5	Q9H0K1	SIK2	S224	L221F	221	Missense	distal	-3	no	1.577	1.546	EPSD	COSMIC	1.318	Down-regulation
CAMK_CAMKL_QIK_SIK2_ST	Q9UQL6	HDAC5	Q9H0K1	SIK2	S224	G230A	230	Missense	distal	6	no	1.577	1.678	EPSD	COSMIC	1.318	Up-regulation
CAMK_CAMKL_QIK_SIK2_ST	Q9UQL6	HDAC5	Q9H0K1	SIK2	S224	S224R	224	Missense	central	0	yes	1.577	0.000	EPSD	COSMIC	1.318	Loss
CAMK_CAMKL_QIK_SIK2_ST	Q9UQL6	HDAC5	Q9H0K1	SIK2	S224	G230R	230	Missense	distal	6	no	1.577	1.788	EPSD	COSMIC;CCLE	1.318	Up-regulation
CAMK_CAMKL_QIK_SIK2_ST	Q9UQL6	HDAC5	Q9H0K1	SIK2	S224	G230D	230	Missense	distal	6	no	1.577	1.695	EPSD	COSMIC;CCLE	1.318	Up-regulation
CAMK_CAMKL_QIK_SIK2_ST	Q9UQL6	HDAC5	Q9H0K1	SIK2	S224	G230S	230	Missense	distal	6	no	1.577	1.714	EPSD	COSMIC	1.318	Up-regulation
CAMK_CAMKL_QIK_SIK2_ST	Q9UQL6	HDAC5	Q9H0K1	SIK2	S259	R255C	255	Missense	distal	-4	no	1.618	1.575	PhosphoSitePlus	COSMIC	1.318	Down-regulation
CAMK_CAMKL_QIK_SIK2_ST	Q9UQL6	HDAC5	Q9H0K1	SIK2	S259	R266C	266	Missense	distal	7	no	1.618	1.577	PhosphoSitePlus	COSMIC	1.318	Down-regulation
CAMK_CAMKL_QIK_SIK2_ST	Q9UQL6	HDAC5	Q9H0K1	SIK2	S259	R266H	266	Missense	distal	7	no	1.618	1.606	PhosphoSitePlus	COSMIC	1.318	Down-regulation
CAMK_CAMKL_QIK_SIK2_ST	Q9UQL6	HDAC5	Q9H0K1	SIK2	S278	R284C	284	Missense	distal	6	no	1.512	1.401	EPSD	COSMIC	1.318	Down-regulation
CAMK_CAMKL_QIK_SIK2_ST	Q9UQL6	HDAC5	Q9H0K1	SIK2	S278	S279N	279	Missense	proximal	1	no	1.512	1.510	EPSD	COSMIC	1.318	Down-regulation
CAMK_CAMKL_QIK_SIK2_ST	Q9UQL6	HDAC5	Q9H0K1	SIK2	S278	R284S	284	Missense	distal	6	no	1.512	1.438	EPSD	COSMIC	1.318	Down-regulation
CAMK_CAMKL_QIK_SIK2_ST	Q9UQL6	HDAC5	Q9H0K1	SIK2	S498	R491W	491	Missense	distal	-7	no	1.502	1.483	EPSD	COSMIC	1.318	Down-regulation
CAMK_CAMKL_QIK_SIK2_ST	Q9UQL6	HDAC5	Q9H0K1	SIK2	S713	R717H	717	Missense	distal	4	no	1.661	1.542	EPSD	COSMIC	1.318	Down-regulation
CAMK_CAMKL_QIK_SIK2_ST	Q9UQL6	HDAC5	Q9H0K1	SIK2	S713	R710Q	710	Missense	distal	-3	no	1.661	1.598	EPSD	COSMIC	1.318	Down-regulation
CAMK_CAMKL_QIK_SIK2_ST	Q9UQL6	HDAC5	Q9H0K1	SIK2	S713	Q719H	719	Missense	distal	6	no	1.661	1.475	EPSD	COSMIC	1.318	Down-regulation
CAMK_CAMKL_QIK_SIK2_ST	Q9UQL6	HDAC5	Q9H0K1	SIK2	S713	S713G	713	Missense	central	0	yes	1.661	0.000	EPSD	COSMIC	1.318	Loss
STE_STE7_MEK3_MAP2K3_ST	P46734	MAP2K3	P46734	MAP2K3	S6	S6W	6	Missense	central	0	yes	0.000	0.000	EPSD	COSMIC	0.000	Loss
STE_STE7_MEK3_MAP2K3_ST	P46734	MAP2K3	P46734	MAP2K3	T39	T39I	39	Missense	central	0	yes	0.000	0.000	EPSD	COSMIC;GDSC	0.000	Loss
STE_STE7_MEK3_MAP2K3_ST	P46734	MAP2K3	P46734	MAP2K3	S46	S46F	46	Missense	central	0	yes	0.000	0.000	EPSD	COSMIC	0.000	Loss
STE_STE7_MEK3_MAP2K3_ST	P46734	MAP2K3	P46734	MAP2K3	T222	T222M	222	Missense	central	0	yes	0.001	0.000	EPSD;PhosphoSitePlus	COSMIC	0.000	Loss
STE_STE7_MEK3_MAP2K3_ST	O15264	MAPK13	P46734	MAP2K3	T265	T265I	265	Missense	central	0	yes	0.000	0.000	EPSD	COSMIC	0.000	Loss
STE_STE7_MEK3_MAP2K3_ST	Q16539	MAPK14	P46734	MAP2K3	T185	T185I	185	Missense	central	0	yes	0.000	0.000	EPSD	COSMIC	0.000	Loss
CMGC_CDK_CDK4_CDK6_ST	P06400	RB1	Q00534	CDK6	T5	P6S	6	Missense	proximal	1	no	85.813	56.174	EPSD	COSMIC	54.510	Down-regulation
CMGC_CDK_CDK4_CDK6_ST	P06400	RB1	Q00534	CDK6	T5	P2S	2	Missense	distal	-3	no	85.813	85.881	EPSD	COSMIC	54.510	Up-regulation
CMGC_CDK_CDK4_CDK6_ST	P06400	RB1	Q00534	CDK6	T5	T5N	5	Missense	central	0	yes	85.813	0.000	EPSD	COSMIC	54.510	Loss
CMGC_CDK_CDK4_CDK6_ST	P06400	RB1	Q00534	CDK6	T5	R7Q	7	Missense	proximal	2	no	85.813	85.807	EPSD	COSMIC	54.510	Down-regulation
CMGC_CDK_CDK4_CDK6_ST	P06400	RB1	Q00534	CDK6	S149	R150S	150	Missense	proximal	1	no	-5.972	54.599	EPSD	COSMIC	54.510	Gain
CMGC_CDK_CDK4_CDK6_ST	P06400	RB1	Q00534	CDK6	S230	K228R	228	Missense	proximal	-2	no	84.487	84.549	EPSD	COSMIC;GDSC;CCLE	54.510	Up-regulation
CMGC_CDK_CDK4_CDK6_ST	P06400	RB1	Q00534	CDK6	S230	I227N	227	Missense	distal	-3	no	84.487	84.495	EPSD	COSMIC	54.510	Up-regulation
CMGC_CDK_CDK4_CDK6_ST	P06400	RB1	Q00534	CDK6	S230	P232L	232	Missense	proximal	2	no	84.487	84.576	EPSD	COSMIC	54.510	Up-regulation
CMGC_CDK_CDK4_CDK6_ST	P06400	RB1	Q00534	CDK6	S249	V243A	243	Missense	distal	-6	no	86.151	86.179	EPSD	COSMIC	54.510	Up-regulation
CMGC_CDK_CDK4_CDK6_ST	P06400	RB1	Q00534	CDK6	S249	P250S	250	Missense	proximal	1	no	86.151	56.512	EPSD	COSMIC	54.510	Down-regulation
CMGC_CDK_CDK4_CDK6_ST	P06400	RB1	Q00534	CDK6	T252	Q257R	257	Missense	distal	5	no	83.890	83.868	EPSD	COSMIC	54.510	Down-regulation
CMGC_CDK_CDK4_CDK6_ST	P06400	RB1	Q00534	CDK6	T252	P250S	250	Missense	proximal	-2	no	83.890	83.945	EPSD	COSMIC	54.510	Up-regulation
CMGC_CDK_CDK4_CDK6_ST	P06400	RB1	Q00534	CDK6	T356	E352K	352	Missense	distal	-4	no	83.463	83.694	EPSD	COSMIC	54.510	Up-regulation
CMGC_CDK_CDK4_CDK6_ST	P06400	RB1	Q00534	CDK6	T356	R358Q	358	Missense	proximal	2	no	83.463	83.457	EPSD	COSMIC;CCLE	54.510	Down-regulation
CMGC_CDK_CDK4_CDK6_ST	P06400	RB1	Q00534	CDK6	T356	N361Y	361	Missense	distal	5	no	83.463	83.432	EPSD	COSMIC	54.510	Down-regulation
CMGC_CDK_CDK4_CDK6_ST	P06400	RB1	Q00534	CDK6	T373	P370S	370	Missense	distal	-3	no	83.353	83.422	EPSD	COSMIC	54.510	Up-regulation
CMGC_CDK_CDK4_CDK6_ST	P06400	RB1	Q00534	CDK6	T373	P374L	374	Missense	proximal	1	no	83.353	-13.654	EPSD	COSMIC	54.510	Loss
CMGC_CDK_CDK4_CDK6_ST	P06400	RB1	Q00534	CDK6	T373	N367D	367	Missense	distal	-6	no	83.353	83.416	EPSD	COSMIC	54.510	Up-regulation
CMGC_CDK_CDK4_CDK6_ST	P06400	RB1	Q00534	CDK6	T373	P370L	370	Missense	distal	-3	no	83.353	83.574	EPSD	COSMIC	54.510	Up-regulation
CMGC_CDK_CDK4_CDK6_ST	P06400	RB1	Q00534	CDK6	S567	W563C	563	Missense	distal	-4	no	83.870	83.889	EPSD	COSMIC	54.510	Up-regulation
CMGC_CDK_CDK4_CDK6_ST	P06400	RB1	Q00534	CDK6	S567	S560P	560	Missense	distal	-7	no	83.870	84.268	EPSD	COSMIC	54.510	Up-regulation
CMGC_CDK_CDK4_CDK6_ST	P06400	RB1	Q00534	CDK6	S567	L564V	564	Missense	distal	-3	no	83.870	83.798	EPSD	COSMIC	54.510	Down-regulation
CMGC_CDK_CDK4_CDK6_ST	P06400	RB1	Q00534	CDK6	S567	L572F	572	Missense	distal	5	no	83.870	83.919	EPSD	COSMIC	54.510	Up-regulation
CMGC_CDK_CDK4_CDK6_ST	P06400	RB1	Q00534	CDK6	S608	R611S	611	Missense	distal	3	no	84.906	87.355	EPSD	COSMIC	54.510	Up-regulation
CMGC_CDK_CDK4_CDK6_ST	P06400	RB1	Q00534	CDK6	S608	S612P	612	Missense	distal	4	no	84.906	84.821	EPSD	COSMIC	54.510	Down-regulation
CMGC_CDK_CDK4_CDK6_ST	P06400	RB1	Q00534	CDK6	S608	Y606C	606	Missense	proximal	-2	no	84.906	84.895	EPSD	COSMIC	54.510	Down-regulation
CMGC_CDK_CDK4_CDK6_ST	P06400	RB1	Q00534	CDK6	S608	P609S	609	Missense	proximal	1	no	84.906	55.267	EPSD	COSMIC	54.510	Down-regulation
CMGC_CDK_CDK4_CDK6_ST	P06400	RB1	Q00534	CDK6	S608	M605T	605	Missense	distal	-3	no	84.906	84.815	EPSD	COSMIC	54.510	Down-regulation
CMGC_CDK_CDK4_CDK6_ST	P06400	RB1	Q00534	CDK6	S608	L607V	607	Missense	proximal	-1	no	84.906	84.946	EPSD	COSMIC	54.510	Up-regulation
CMGC_CDK_CDK4_CDK6_ST	P06400	RB1	Q00534	CDK6	S608	L607I	607	Missense	proximal	-1	no	84.906	84.929	EPSD	COSMIC	54.510	Up-regulation
CMGC_CDK_CDK4_CDK6_ST	P06400	RB1	Q00534	CDK6	S612	R611S	611	Missense	proximal	-1	no	86.965	87.043	EPSD;PhosphoSitePlus	COSMIC	54.510	Up-regulation
CMGC_CDK_CDK4_CDK6_ST	P06400	RB1	Q00534	CDK6	S612	S612P	612	Missense	central	0	yes	86.965	0.000	EPSD;PhosphoSitePlus	COSMIC	54.510	Loss
CMGC_CDK_CDK4_CDK6_ST	P06400	RB1	Q00534	CDK6	S612	Y606C	606	Missense	distal	-6	no	86.965	86.949	EPSD;PhosphoSitePlus	COSMIC	54.510	Down-regulation
CMGC_CDK_CDK4_CDK6_ST	P06400	RB1	Q00534	CDK6	S612	P609S	609	Missense	distal	-3	no	86.965	87.033	EPSD;PhosphoSitePlus	COSMIC	54.510	Up-regulation
CMGC_CDK_CDK4_CDK6_ST	P06400	RB1	Q00534	CDK6	S612	M605T	605	Missense	distal	-7	no	86.965	87.543	EPSD;PhosphoSitePlus	COSMIC	54.510	Up-regulation
CMGC_CDK_CDK4_CDK6_ST	P06400	RB1	Q00534	CDK6	S612	L607V	607	Missense	distal	-5	no	86.965	86.837	EPSD;PhosphoSitePlus	COSMIC	54.510	Down-regulation
CMGC_CDK_CDK4_CDK6_ST	P06400	RB1	Q00534	CDK6	S612	L607I	607	Missense	distal	-5	no	86.965	86.900	EPSD;PhosphoSitePlus	COSMIC	54.510	Down-regulation
CMGC_CDK_CDK4_CDK6_ST	P06400	RB1	Q00534	CDK6	T620	R621S	621	Missense	proximal	1	no	-5.583	54.988	EPSD	COSMIC;GDSC	54.510	Gain
CMGC_CDK_CDK4_CDK6_ST	P06400	RB1	Q00534	CDK6	T620	R621P	621	Missense	proximal	1	no	-5.583	84.627	EPSD	COSMIC	54.510	Gain
CMGC_CDK_CDK4_CDK6_ST	P06400	RB1	Q00534	CDK6	T633	S634P	634	Missense	proximal	1	no	54.151	83.790	EPSD	COSMIC	54.510	Gain
CMGC_CDK_CDK4_CDK6_ST	P06400	RB1	Q00534	CDK6	S780	P776R	776	Missense	distal	-4	no	87.105	86.053	PhosphoSitePlus;EPSD	COSMIC	54.510	Down-regulation
CMGC_CDK_CDK4_CDK6_ST	P06400	RB1	Q00534	CDK6	S780	P777S	777	Missense	distal	-3	no	87.105	87.173	PhosphoSitePlus;EPSD	COSMIC	54.510	Up-regulation
CMGC_CDK_CDK4_CDK6_ST	P06400	RB1	Q00534	CDK6	S780	P786S	786	Missense	distal	6	no	87.105	87.093	PhosphoSitePlus;EPSD	COSMIC	54.510	Down-regulation
CMGC_CDK_CDK4_CDK6_ST	P06400	RB1	Q00534	CDK6	S780	S773F	773	Missense	distal	-7	no	87.105	86.338	PhosphoSitePlus;EPSD	COSMIC	54.510	Down-regulation
CMGC_CDK_CDK4_CDK6_ST	P06400	RB1	Q00534	CDK6	S788	S795L	795	Missense	distal	7	no	88.702	88.245	EPSD;PhosphoSitePlus	COSMIC	54.510	Down-regulation
CMGC_CDK_CDK4_CDK6_ST	P06400	RB1	Q00534	CDK6	S788	H784Y	784	Missense	distal	-4	no	88.702	88.647	EPSD;PhosphoSitePlus	COSMIC	54.510	Down-regulation
CMGC_CDK_CDK4_CDK6_ST	P06400	RB1	Q00534	CDK6	S788	S794I	794	Missense	distal	6	no	88.702	88.667	EPSD;PhosphoSitePlus	COSMIC	54.510	Down-regulation
CMGC_CDK_CDK4_CDK6_ST	P06400	RB1	Q00534	CDK6	S788	P786S	786	Missense	proximal	-2	no	88.702	88.757	EPSD;PhosphoSitePlus	COSMIC	54.510	Up-regulation
CMGC_CDK_CDK4_CDK6_ST	P06400	RB1	Q00534	CDK6	S788	P793S	793	Missense	distal	5	no	88.702	88.635	EPSD;PhosphoSitePlus	COSMIC;CCLE	54.510	Down-regulation
CMGC_CDK_CDK4_CDK6_ST	P06400	RB1	Q00534	CDK6	S795	S795L	795	Missense	central	0	yes	86.408	0.000	EPSD;PhosphoSitePlus	COSMIC	54.510	Loss
CMGC_CDK_CDK4_CDK6_ST	P06400	RB1	Q00534	CDK6	S795	G802R	802	Missense	distal	7	no	86.408	86.407	EPSD;PhosphoSitePlus	COSMIC	54.510	Down-regulation
CMGC_CDK_CDK4_CDK6_ST	P06400	RB1	Q00534	CDK6	S795	R798Q	798	Missense	distal	3	no	86.408	86.351	EPSD;PhosphoSitePlus	COSMIC;GDSC;CCLE	54.510	Down-regulation
CMGC_CDK_CDK4_CDK6_ST	P06400	RB1	Q00534	CDK6	S795	S794I	794	Missense	proximal	-1	no	86.408	86.348	EPSD;PhosphoSitePlus	COSMIC	54.510	Down-regulation
CMGC_CDK_CDK4_CDK6_ST	P06400	RB1	Q00534	CDK6	S795	G801A	801	Missense	distal	6	no	86.408	86.424	EPSD;PhosphoSitePlus	COSMIC	54.510	Up-regulation
CMGC_CDK_CDK4_CDK6_ST	P06400	RB1	Q00534	CDK6	S795	P793S	793	Missense	proximal	-2	no	86.408	86.463	EPSD;PhosphoSitePlus	COSMIC;CCLE	54.510	Up-regulation
CMGC_CDK_CDK4_CDK6_ST	P06400	RB1	Q00534	CDK6	S807	G802R	802	Missense	distal	-5	no	90.350	90.338	EPSD;PhosphoSitePlus	COSMIC	54.510	Down-regulation
CMGC_CDK_CDK4_CDK6_ST	P06400	RB1	Q00534	CDK6	S807	K814T	814	Missense	distal	7	no	90.350	90.458	EPSD;PhosphoSitePlus	COSMIC	54.510	Up-regulation
CMGC_CDK_CDK4_CDK6_ST	P06400	RB1	Q00534	CDK6	S807	G801A	801	Missense	distal	-6	no	90.350	90.289	EPSD;PhosphoSitePlus	COSMIC	54.510	Down-regulation
CMGC_CDK_CDK4_CDK6_ST	P06400	RB1	Q00534	CDK6	S811	G818S	818	Missense	distal	7	no	88.820	89.235	EPSD;PhosphoSitePlus	COSMIC	54.510	Up-regulation
CMGC_CDK_CDK4_CDK6_ST	P06400	RB1	Q00534	CDK6	S811	G818C	818	Missense	distal	7	no	88.820	88.869	EPSD;PhosphoSitePlus	COSMIC	54.510	Up-regulation
CMGC_CDK_CDK4_CDK6_ST	P06400	RB1	Q00534	CDK6	S811	K814T	814	Missense	distal	3	no	88.820	88.866	EPSD;PhosphoSitePlus	COSMIC	54.510	Up-regulation
CMGC_CDK_CDK4_CDK6_ST	P06400	RB1	Q00534	CDK6	T821	G818S	818	Missense	distal	-3	no	86.637	86.470	EPSD;PhosphoSitePlus	COSMIC	54.510	Down-regulation
CMGC_CDK_CDK4_CDK6_ST	P06400	RB1	Q00534	CDK6	T821	P822S	822	Missense	proximal	1	no	86.637	56.999	EPSD;PhosphoSitePlus	COSMIC	54.510	Down-regulation
CMGC_CDK_CDK4_CDK6_ST	P06400	RB1	Q00534	CDK6	T821	G818C	818	Missense	distal	-3	no	86.637	86.600	EPSD;PhosphoSitePlus	COSMIC	54.510	Down-regulation
CMGC_CDK_CDK4_CDK6_ST	P06400	RB1	Q00534	CDK6	T821	K814T	814	Missense	distal	-7	no	86.637	86.982	EPSD;PhosphoSitePlus	COSMIC	54.510	Up-regulation
CMGC_CDK_CDK4_CDK6_ST	P06400	RB1	Q00534	CDK6	T826	S829L	829	Missense	distal	3	no	88.837	86.328	EPSD;PhosphoSitePlus	COSMIC	54.510	Down-regulation
CMGC_CDK_CDK4_CDK6_ST	P06400	RB1	Q00534	CDK6	T826	P822S	822	Missense	distal	-4	no	88.837	88.259	EPSD;PhosphoSitePlus	COSMIC	54.510	Down-regulation
CMGC_CDK_CDK4_CDK6_ST	P06400	RB1	Q00534	CDK6	T841	I848R	848	Missense	distal	7	no	57.504	57.427	EPSD	COSMIC	54.510	Down-regulation
CMGC_CDK_CDK4_CDK6_ST	P06400	RB1	Q00534	CDK6	T841	F839L	839	Missense	proximal	-2	no	57.504	57.523	EPSD	COSMIC	54.510	Up-regulation
CMGC_CDK_CDK4_CDK6_ST	P06400	RB1	Q00534	CDK6	T841	G840V	840	Missense	proximal	-1	no	57.504	57.540	EPSD	COSMIC	54.510	Up-regulation
CMGC_CDK_CDK4_CDK6_ST	P06400	RB1	Q00534	CDK6	T841	S842F	842	Missense	proximal	1	no	57.504	-2.865	EPSD	COSMIC	54.510	Loss
CMGC_CDK_CDK4_CDK6_ST	P06400	RB1	Q00534	CDK6	T922	D918N	918	Missense	distal	-4	no	55.884	56.242	EPSD	COSMIC	54.510	Up-regulation
CMGC_CDK_CDK4_CDK6_ST	Q08999	RBL2	Q00534	CDK6	S40	Q44R	44	Missense	distal	4	no	86.652	86.653	EPSD	COSMIC	54.510	Up-regulation
CMGC_CDK_CDK4_CDK6_ST	Q08999	RBL2	Q00534	CDK6	T42	Q44R	44	Missense	proximal	2	no	84.864	84.870	EPSD	COSMIC	54.510	Up-regulation
CMGC_CDK_CDK4_CDK6_ST	Q08999	RBL2	Q00534	CDK6	T401	Y408C	408	Missense	distal	7	no	86.217	86.258	PhosphoSitePlus;EPSD	COSMIC	54.510	Up-regulation
CMGC_CDK_CDK4_CDK6_ST	Q08999	RBL2	Q00534	CDK6	S413	P414L	414	Missense	proximal	1	no	86.076	-10.931	EPSD	COSMIC	54.510	Loss
CMGC_CDK_CDK4_CDK6_ST	Q08999	RBL2	Q00534	CDK6	S413	P414H	414	Missense	proximal	1	no	86.076	-7.049	EPSD	COSMIC	54.510	Loss
CMGC_CDK_CDK4_CDK6_ST	Q08999	RBL2	Q00534	CDK6	S413	S413R	413	Missense	central	0	yes	86.076	0.000	EPSD	COSMIC	54.510	Loss
CMGC_CDK_CDK4_CDK6_ST	Q08999	RBL2	Q00534	CDK6	S413	Y408C	408	Missense	distal	-5	no	86.076	86.034	EPSD	COSMIC	54.510	Down-regulation
CMGC_CDK_CDK4_CDK6_ST	Q08999	RBL2	Q00534	CDK6	T417	P414L	414	Missense	distal	-3	no	86.030	86.251	EPSD	COSMIC	54.510	Up-regulation
CMGC_CDK_CDK4_CDK6_ST	Q08999	RBL2	Q00534	CDK6	T417	P414H	414	Missense	distal	-3	no	86.030	86.250	EPSD	COSMIC	54.510	Up-regulation
CMGC_CDK_CDK4_CDK6_ST	Q08999	RBL2	Q00534	CDK6	T417	S413R	413	Missense	distal	-4	no	86.030	85.557	EPSD	COSMIC	54.510	Down-regulation
CMGC_CDK_CDK4_CDK6_ST	Q08999	RBL2	Q00534	CDK6	S427	R428S	428	Missense	proximal	1	no	-5.194	55.377	EPSD	COSMIC	54.510	Gain
CMGC_CDK_CDK4_CDK6_ST	Q08999	RBL2	Q00534	CDK6	S603	W606C	606	Missense	distal	3	no	82.154	82.066	EPSD	COSMIC	54.510	Down-regulation
CMGC_CDK_CDK4_CDK6_ST	Q08999	RBL2	Q00534	CDK6	S603	I609N	609	Missense	distal	6	no	82.154	82.150	EPSD	COSMIC	54.510	Down-regulation
CMGC_CDK_CDK4_CDK6_ST	Q08999	RBL2	Q00534	CDK6	S639	P643S	643	Missense	distal	4	no	84.083	84.168	EPSD	COSMIC	54.510	Up-regulation
CMGC_CDK_CDK4_CDK6_ST	Q08999	RBL2	Q00534	CDK6	T642	E648G	648	Missense	distal	6	no	85.009	84.993	EPSD	COSMIC	54.510	Down-regulation
CMGC_CDK_CDK4_CDK6_ST	Q08999	RBL2	Q00534	CDK6	T642	P643S	643	Missense	proximal	1	no	85.009	55.370	EPSD	COSMIC	54.510	Down-regulation
CMGC_CDK_CDK4_CDK6_ST	Q08999	RBL2	Q00534	CDK6	S688	E685Q	685	Missense	distal	-3	no	84.753	84.789	EPSD	COSMIC	54.510	Up-regulation
CMGC_CDK_CDK4_CDK6_ST	Q08999	RBL2	Q00534	CDK6	S688	T694M	694	Missense	distal	6	no	84.753	84.706	EPSD	COSMIC	54.510	Down-regulation
CMGC_CDK_CDK4_CDK6_ST	Q08999	RBL2	Q00534	CDK6	T694	R697H	697	Missense	distal	3	no	84.290	84.416	EPSD	COSMIC	54.510	Up-regulation
CMGC_CDK_CDK4_CDK6_ST	Q08999	RBL2	Q00534	CDK6	T694	P699S	699	Missense	distal	5	no	84.290	84.223	EPSD	COSMIC	54.510	Down-regulation
CMGC_CDK_CDK4_CDK6_ST	Q08999	RBL2	Q00534	CDK6	T694	T694M	694	Missense	central	0	yes	84.290	0.000	EPSD	COSMIC	54.510	Loss
CMGC_CDK_CDK4_CDK6_ST	Q08999	RBL2	Q00534	CDK6	S952	K958R	958	Missense	distal	6	no	84.898	84.866	EPSD	COSMIC	54.510	Down-regulation
CMGC_CDK_CDK4_CDK6_ST	Q08999	RBL2	Q00534	CDK6	S952	S948G	948	Missense	distal	-4	no	84.898	84.545	EPSD	COSMIC	54.510	Down-regulation
CMGC_CDK_CDK4_CDK6_ST	Q08999	RBL2	Q00534	CDK6	T961	K958R	958	Missense	distal	-3	no	56.597	56.655	EPSD	COSMIC	54.510	Up-regulation
CMGC_CDK_CDK4_CDK6_ST	Q08999	RBL2	Q00534	CDK6	T961	R963T	963	Missense	proximal	2	no	56.597	56.530	EPSD	COSMIC	54.510	Down-regulation
CMGC_CDK_CDK4_CDK6_ST	Q08999	RBL2	Q00534	CDK6	S965	K958R	958	Missense	distal	-7	no	58.209	57.871	EPSD	COSMIC	54.510	Down-regulation
CMGC_CDK_CDK4_CDK6_ST	Q08999	RBL2	Q00534	CDK6	S965	R963T	963	Missense	proximal	-2	no	58.209	58.089	EPSD	COSMIC	54.510	Down-regulation
CMGC_CDK_CDK4_CDK6_ST	Q08999	RBL2	Q00534	CDK6	S965	S972G	972	Missense	distal	7	no	58.209	57.793	EPSD	COSMIC	54.510	Down-regulation
CMGC_CDK_CDK4_CDK6_ST	Q08999	RBL2	Q00534	CDK6	S966	R963T	963	Missense	distal	-3	no	86.206	86.085	EPSD	COSMIC	54.510	Down-regulation
CMGC_CDK_CDK4_CDK6_ST	Q08999	RBL2	Q00534	CDK6	S966	S972G	972	Missense	distal	6	no	86.206	86.151	EPSD	COSMIC	54.510	Down-regulation
CMGC_CDK_CDK4_CDK6_ST	Q08999	RBL2	Q00534	CDK6	S971	S972G	972	Missense	proximal	1	no	59.408	-2.269	EPSD	COSMIC	54.510	Loss
CMGC_CDK_CDK4_CDK6_ST	Q08999	RBL2	Q00534	CDK6	S972	S972G	972	Missense	central	0	yes	54.623	0.000	EPSD	COSMIC	54.510	Loss
CMGC_CDK_CDK4_CDK6_ST	Q08999	RBL2	Q00534	CDK6	S981	S982N	982	Missense	proximal	1	no	56.540	0.841	EPSD	COSMIC	54.510	Loss
CMGC_CDK_CDK4_CDK6_ST	Q08999	RBL2	Q00534	CDK6	T986	S982N	982	Missense	distal	-4	no	82.610	82.290	EPSD	COSMIC	54.510	Down-regulation
CMGC_CDK_CDK4_CDK6_ST	Q08999	RBL2	Q00534	CDK6	S1035	S1035Y	1035	Missense	central	0	yes	86.166	0.000	EPSD;PhosphoSitePlus	COSMIC	54.510	Loss
CMGC_CDK_CDK4_CDK6_ST	Q08999	RBL2	Q00534	CDK6	S1035	P1036L	1036	Missense	proximal	1	no	86.166	-10.842	EPSD;PhosphoSitePlus	COSMIC;CCLE	54.510	Loss
CMGC_CDK_CDK4_CDK6_ST	Q08999	RBL2	Q00534	CDK6	S1044	R1046H	1046	Missense	proximal	2	no	84.936	84.937	EPSD	COSMIC	54.510	Up-regulation
CMGC_CDK_CDK4_CDK6_ST	Q08999	RBL2	Q00534	CDK6	S1044	R1046C	1046	Missense	proximal	2	no	84.936	84.926	EPSD	COSMIC	54.510	Down-regulation
CMGC_CDK_CDK4_CDK6_ST	Q08999	RBL2	Q00534	CDK6	S1044	I1048K	1048	Missense	distal	4	no	84.936	84.880	EPSD	COSMIC	54.510	Down-regulation
CMGC_CDK_CDK4_CDK6_ST	Q08999	RBL2	Q00534	CDK6	S1044	S1044F	1044	Missense	central	0	yes	84.936	0.000	EPSD	COSMIC	54.510	Loss
CMGC_CDK_CDK4_CDK6_ST	Q08999	RBL2	Q00534	CDK6	S1044	R1047Q	1047	Missense	distal	3	no	84.936	84.879	EPSD	COSMIC	54.510	Down-regulation
CMGC_CDK_CDK4_CDK6_ST	Q08999	RBL2	Q00534	CDK6	S1059	T1065K	1065	Missense	distal	6	no	84.655	84.623	EPSD	COSMIC	54.510	Down-regulation
CMGC_CDK_CDK4_CDK6_ST	Q08999	RBL2	Q00534	CDK6	S1059	H1061Q	1061	Missense	proximal	2	no	84.655	84.649	EPSD	COSMIC	54.510	Down-regulation
CMGC_CDK_CDK4_CDK6_ST	Q08999	RBL2	Q00534	CDK6	S1068	T1065K	1065	Missense	distal	-3	no	85.983	86.046	EPSD	COSMIC	54.510	Up-regulation
CMGC_CDK_CDK4_CDK6_ST	Q08999	RBL2	Q00534	CDK6	S1068	H1061Q	1061	Missense	distal	-7	no	85.983	86.047	EPSD	COSMIC	54.510	Up-regulation
CMGC_CDK_CDK4_CDK6_ST	Q08999	RBL2	Q00534	CDK6	S1080	K1083N	1083	Missense	distal	3	no	85.244	84.220	EPSD	COSMIC	54.510	Down-regulation
CMGC_CDK_CDK4_CDK6_ST	Q08999	RBL2	Q00534	CDK6	T1097	K1100N	1100	Missense	distal	3	no	85.210	84.186	EPSD	COSMIC	54.510	Down-regulation
CMGC_CDK_CDK4_CDK6_ST	Q08999	RBL2	Q00534	CDK6	T1097	S1090I	1090	Missense	distal	-7	no	85.210	84.724	EPSD	COSMIC	54.510	Down-regulation
CMGC_CDK_CDK4_CDK6_ST	Q08999	RBL2	Q00534	CDK6	T1097	I1092M	1092	Missense	distal	-5	no	85.210	85.195	EPSD	COSMIC	54.510	Down-regulation
CMGC_CDK_CDK4_CDK6_ST	Q08999	RBL2	Q00534	CDK6	T1097	R1093H	1093	Missense	distal	-4	no	85.210	85.238	EPSD	COSMIC	54.510	Up-regulation
CMGC_CDK_CDK4_CDK6_ST	Q08999	RBL2	Q00534	CDK6	S1112	L1106F	1106	Missense	distal	-6	no	84.949	84.923	EPSD	COSMIC	54.510	Down-regulation
CMGC_CDK_CDK4_CDK6_ST	Q08999	RBL2	Q00534	CDK6	S1112	P1113S	1113	Missense	proximal	1	no	84.949	55.310	EPSD	COSMIC	54.510	Down-regulation
CMGC_CDK_CDK4_CDK6_ST	Q08050	FOXM1	Q00534	CDK6	T3	R6S	6	Missense	distal	3	no	54.355	56.804	EPSD	COSMIC	54.510	Gain
CMGC_CDK_CDK4_CDK6_ST	Q08050	FOXM1	Q00534	CDK6	S4	R6S	6	Missense	proximal	2	no	83.217	83.140	EPSD	COSMIC	54.510	Down-regulation
CMGC_CDK_CDK4_CDK6_ST	Q08050	FOXM1	Q00534	CDK6	S35	E31K	31	Missense	distal	-4	no	86.767	86.998	EPSD	COSMIC	54.510	Up-regulation
CMGC_CDK_CDK4_CDK6_ST	Q08050	FOXM1	Q00534	CDK6	S331	F324L	324	Missense	distal	-7	no	83.521	83.540	EPSD	COSMIC;GDSC;CCLE	54.510	Up-regulation
CMGC_CDK_CDK4_CDK6_ST	Q08050	FOXM1	Q00534	CDK6	S331	P332A	332	Missense	proximal	1	no	83.521	2.886	EPSD	COSMIC	54.510	Loss
CMGC_CDK_CDK4_CDK6_ST	Q08050	FOXM1	Q00534	CDK6	S434	E441Q	441	Missense	distal	7	no	54.531	54.466	EPSD	COSMIC	54.510	Loss
CMGC_CDK_CDK4_CDK6_ST	Q08050	FOXM1	Q00534	CDK6	S434	E427K	427	Missense	distal	-7	no	54.531	54.660	EPSD	COSMIC	54.510	Up-regulation
CMGC_CDK_CDK4_CDK6_ST	Q08050	FOXM1	Q00534	CDK6	S451	E448K	448	Missense	distal	-3	no	87.017	87.001	EPSD;PhosphoSitePlus	COSMIC	54.510	Down-regulation
CMGC_CDK_CDK4_CDK6_ST	Q08050	FOXM1	Q00534	CDK6	S451	P455L	455	Missense	distal	4	no	87.017	87.243	EPSD;PhosphoSitePlus	COSMIC	54.510	Up-regulation
CMGC_CDK_CDK4_CDK6_ST	Q08050	FOXM1	Q00534	CDK6	S451	P455S	455	Missense	distal	4	no	87.017	87.101	EPSD;PhosphoSitePlus	COSMIC	54.510	Up-regulation
CMGC_CDK_CDK4_CDK6_ST	Q08050	FOXM1	Q00534	CDK6	S451	F450L	450	Missense	proximal	-1	no	87.017	87.008	EPSD;PhosphoSitePlus	COSMIC	54.510	Down-regulation
CMGC_CDK_CDK4_CDK6_ST	Q08050	FOXM1	Q00534	CDK6	S481	E486Q	486	Missense	distal	5	no	86.427	86.366	EPSD	COSMIC	54.510	Down-regulation
CMGC_CDK_CDK4_CDK6_ST	Q08050	FOXM1	Q00534	CDK6	S481	R475T	475	Missense	distal	-6	no	86.427	86.321	EPSD	COSMIC	54.510	Down-regulation
CMGC_CDK_CDK4_CDK6_ST	Q08050	FOXM1	Q00534	CDK6	S481	E480K	480	Missense	proximal	-1	no	86.427	86.439	EPSD	COSMIC	54.510	Up-regulation
CMGC_CDK_CDK4_CDK6_ST	Q08050	FOXM1	Q00534	CDK6	S489	E486Q	486	Missense	distal	-3	no	89.135	89.170	EPSD;PhosphoSitePlus	COSMIC	54.510	Up-regulation
CMGC_CDK_CDK4_CDK6_ST	Q08050	FOXM1	Q00534	CDK6	S489	P492L	492	Missense	distal	3	no	89.135	86.959	EPSD;PhosphoSitePlus	COSMIC	54.510	Down-regulation
CMGC_CDK_CDK4_CDK6_ST	Q08050	FOXM1	Q00534	CDK6	S505	S505L	505	Missense	central	0	yes	57.402	0.000	EPSD	COSMIC	54.510	Loss
CMGC_CDK_CDK4_CDK6_ST	Q08050	FOXM1	Q00534	CDK6	S505	T510N	510	Missense	distal	5	no	57.402	57.243	EPSD	COSMIC;CCLE	54.510	Down-regulation
CMGC_CDK_CDK4_CDK6_ST	Q08050	FOXM1	Q00534	CDK6	S508	S505L	505	Missense	distal	-3	no	88.172	88.324	EPSD;PhosphoSitePlus	COSMIC	54.510	Up-regulation
CMGC_CDK_CDK4_CDK6_ST	Q08050	FOXM1	Q00534	CDK6	S508	T510N	510	Missense	proximal	2	no	88.172	88.225	EPSD;PhosphoSitePlus	COSMIC;CCLE	54.510	Up-regulation
CMGC_CDK_CDK4_CDK6_ST	Q08050	FOXM1	Q00534	CDK6	T510	S505L	505	Missense	distal	-5	no	86.373	86.578	PhosphoSitePlus;EPSD	COSMIC	54.510	Up-regulation
CMGC_CDK_CDK4_CDK6_ST	Q08050	FOXM1	Q00534	CDK6	T510	T510N	510	Missense	central	0	yes	86.373	0.000	PhosphoSitePlus;EPSD	COSMIC;CCLE	54.510	Loss
CMGC_CDK_CDK4_CDK6_ST	Q08050	FOXM1	Q00534	CDK6	S522	R521M	521	Missense	proximal	-1	no	88.258	88.277	EPSD;PhosphoSitePlus	COSMIC	54.510	Up-regulation
CMGC_CDK_CDK4_CDK6_ST	Q08050	FOXM1	Q00534	CDK6	S522	T524S	524	Missense	proximal	2	no	88.258	88.248	EPSD;PhosphoSitePlus	COSMIC	54.510	Down-regulation
CMGC_CDK_CDK4_CDK6_ST	Q08050	FOXM1	Q00534	CDK6	S522	S518I	518	Missense	distal	-4	no	88.258	87.893	EPSD;PhosphoSitePlus	COSMIC	54.510	Down-regulation
CMGC_CDK_CDK4_CDK6_ST	Q08050	FOXM1	Q00534	CDK6	S522	V527A	527	Missense	distal	5	no	88.258	88.202	EPSD;PhosphoSitePlus	COSMIC	54.510	Down-regulation
CMGC_CDK_CDK4_CDK6_ST	Q08050	FOXM1	Q00534	CDK6	S522	R525W	525	Missense	distal	3	no	88.258	88.636	EPSD;PhosphoSitePlus	COSMIC	54.510	Up-regulation
CMGC_CDK_CDK4_CDK6_ST	Q08050	FOXM1	Q00534	CDK6	S522	C526S	526	Missense	distal	4	no	88.258	88.136	EPSD;PhosphoSitePlus	COSMIC	54.510	Down-regulation
CMGC_CDK_CDK4_CDK6_ST	Q08050	FOXM1	Q00534	CDK6	S581	A579S	579	Missense	proximal	-2	no	58.120	57.986	EPSD	COSMIC	54.510	Down-regulation
CMGC_CDK_CDK4_CDK6_ST	Q08050	FOXM1	Q00534	CDK6	S581	S586T	586	Missense	distal	5	no	58.120	57.983	EPSD	COSMIC	54.510	Down-regulation
CMGC_CDK_CDK4_CDK6_ST	Q08050	FOXM1	Q00534	CDK6	S581	S581C	581	Missense	central	0	yes	58.120	0.000	EPSD	COSMIC	54.510	Loss
CMGC_CDK_CDK4_CDK6_ST	Q08050	FOXM1	Q00534	CDK6	S581	P584S	584	Missense	distal	3	no	58.120	58.454	EPSD	COSMIC	54.510	Up-regulation
CMGC_CDK_CDK4_CDK6_ST	Q08050	FOXM1	Q00534	CDK6	S581	F577I	577	Missense	distal	-4	no	58.120	58.274	EPSD	COSMIC	54.510	Up-regulation
CMGC_CDK_CDK4_CDK6_ST	Q08050	FOXM1	Q00534	CDK6	S581	S582F	582	Missense	proximal	1	no	58.120	-2.249	EPSD	COSMIC	54.510	Loss
CMGC_CDK_CDK4_CDK6_ST	Q08050	FOXM1	Q00534	CDK6	T600	T605M	605	Missense	distal	5	no	86.095	85.949	EPSD;PhosphoSitePlus	COSMIC	54.510	Down-regulation
CMGC_CDK_CDK4_CDK6_ST	Q08050	FOXM1	Q00534	CDK6	S609	S615Y	615	Missense	distal	6	no	57.698	57.646	EPSD	COSMIC	54.510	Down-regulation
CMGC_CDK_CDK4_CDK6_ST	Q08050	FOXM1	Q00534	CDK6	S609	S610T	610	Missense	proximal	1	no	57.698	18.730	EPSD	COSMIC	54.510	Loss
CMGC_CDK_CDK4_CDK6_ST	Q08050	FOXM1	Q00534	CDK6	S609	T605M	605	Missense	distal	-4	no	57.698	57.198	EPSD	COSMIC	54.510	Down-regulation
CMGC_CDK_CDK4_CDK6_ST	Q08050	FOXM1	Q00534	CDK6	T611	S615Y	615	Missense	distal	4	no	88.148	88.291	EPSD;PhosphoSitePlus	COSMIC	54.510	Up-regulation
CMGC_CDK_CDK4_CDK6_ST	Q08050	FOXM1	Q00534	CDK6	T611	S610T	610	Missense	proximal	-1	no	88.148	88.126	EPSD;PhosphoSitePlus	COSMIC	54.510	Down-regulation
CMGC_CDK_CDK4_CDK6_ST	Q08050	FOXM1	Q00534	CDK6	T611	T605M	605	Missense	distal	-6	no	88.148	88.219	EPSD;PhosphoSitePlus	COSMIC	54.510	Up-regulation
CMGC_CDK_CDK4_CDK6_ST	Q08050	FOXM1	Q00534	CDK6	T620	S615Y	615	Missense	distal	-5	no	87.706	87.893	EPSD;PhosphoSitePlus	COSMIC	54.510	Up-regulation
CMGC_CDK_CDK4_CDK6_ST	Q08050	FOXM1	Q00534	CDK6	T620	P621L	621	Missense	proximal	1	no	87.706	-9.301	EPSD;PhosphoSitePlus	COSMIC	54.510	Loss
CMGC_CDK_CDK4_CDK6_ST	Q08050	FOXM1	Q00534	CDK6	T620	W624C	624	Missense	distal	4	no	87.706	87.705	EPSD;PhosphoSitePlus	COSMIC	54.510	Down-regulation
CMGC_CDK_CDK4_CDK6_ST	Q08050	FOXM1	Q00534	CDK6	T627	P621L	621	Missense	distal	-6	no	88.014	88.244	EPSD;PhosphoSitePlus	COSMIC	54.510	Up-regulation
CMGC_CDK_CDK4_CDK6_ST	Q08050	FOXM1	Q00534	CDK6	T627	V632G	632	Missense	distal	5	no	88.014	87.897	EPSD;PhosphoSitePlus	COSMIC	54.510	Down-regulation
CMGC_CDK_CDK4_CDK6_ST	Q08050	FOXM1	Q00534	CDK6	T627	G633E	633	Missense	distal	6	no	88.014	88.031	EPSD;PhosphoSitePlus	COSMIC	54.510	Up-regulation
CMGC_CDK_CDK4_CDK6_ST	Q08050	FOXM1	Q00534	CDK6	T627	W624C	624	Missense	distal	-3	no	88.014	88.015	EPSD;PhosphoSitePlus	COSMIC	54.510	Up-regulation
CMGC_CDK_CDK4_CDK6_ST	Q08050	FOXM1	Q00534	CDK6	S638	D636H	636	Missense	proximal	-2	no	84.644	84.613	EPSD	COSMIC	54.510	Down-regulation
CMGC_CDK_CDK4_CDK6_ST	Q08050	FOXM1	Q00534	CDK6	S638	S643P	643	Missense	distal	5	no	84.644	84.710	EPSD	COSMIC	54.510	Up-regulation
CMGC_CDK_CDK4_CDK6_ST	Q08050	FOXM1	Q00534	CDK6	S638	V632G	632	Missense	distal	-6	no	84.644	84.732	EPSD	COSMIC	54.510	Up-regulation
CMGC_CDK_CDK4_CDK6_ST	Q08050	FOXM1	Q00534	CDK6	S638	G633E	633	Missense	distal	-5	no	84.644	84.576	EPSD	COSMIC	54.510	Down-regulation
CMGC_CDK_CDK4_CDK6_ST	Q08050	FOXM1	Q00534	CDK6	T662	P663H	663	Missense	proximal	1	no	85.515	-7.611	EPSD	COSMIC	54.510	Loss
CMGC_CDK_CDK4_CDK6_ST	Q08050	FOXM1	Q00534	CDK6	T662	L659P	659	Missense	distal	-3	no	85.515	85.294	EPSD	COSMIC	54.510	Down-regulation
CMGC_CDK_CDK4_CDK6_ST	Q08050	FOXM1	Q00534	CDK6	T662	S666N	666	Missense	distal	4	no	85.515	85.627	EPSD	COSMIC	54.510	Up-regulation
CMGC_CDK_CDK4_CDK6_ST	Q08050	FOXM1	Q00534	CDK6	T662	P669L	669	Missense	distal	7	no	85.515	85.189	EPSD	COSMIC	54.510	Down-regulation
CMGC_CDK_CDK4_CDK6_ST	Q08050	FOXM1	Q00534	CDK6	S672	P673S	673	Missense	proximal	1	no	87.854	58.215	EPSD	COSMIC	54.510	Down-regulation
CMGC_CDK_CDK4_CDK6_ST	Q08050	FOXM1	Q00534	CDK6	S672	R675K	675	Missense	distal	3	no	87.854	89.031	EPSD	COSMIC	54.510	Up-regulation
CMGC_CDK_CDK4_CDK6_ST	Q08050	FOXM1	Q00534	CDK6	S672	S666N	666	Missense	distal	-6	no	87.854	88.038	EPSD	COSMIC	54.510	Up-regulation
CMGC_CDK_CDK4_CDK6_ST	Q08050	FOXM1	Q00534	CDK6	S672	P669L	669	Missense	distal	-3	no	87.854	88.075	EPSD	COSMIC	54.510	Up-regulation
CMGC_CDK_CDK4_CDK6_ST	Q08050	FOXM1	Q00534	CDK6	S672	L670P	670	Missense	proximal	-2	no	87.854	87.613	EPSD	COSMIC	54.510	Down-regulation
CMGC_CDK_CDK4_CDK6_ST	Q08050	FOXM1	Q00534	CDK6	S678	P673S	673	Missense	distal	-5	no	58.308	58.351	EPSD	COSMIC	54.510	Up-regulation
CMGC_CDK_CDK4_CDK6_ST	Q08050	FOXM1	Q00534	CDK6	S678	R675K	675	Missense	distal	-3	no	58.308	58.250	EPSD	COSMIC	54.510	Down-regulation
CMGC_CDK_CDK4_CDK6_ST	Q08050	FOXM1	Q00534	CDK6	S692	S695L	695	Missense	distal	3	no	58.315	55.805	EPSD	COSMIC	54.510	Down-regulation
CMGC_CDK_CDK4_CDK6_ST	Q08050	FOXM1	Q00534	CDK6	S692	P688S	688	Missense	distal	-4	no	58.315	57.736	EPSD	COSMIC	54.510	Down-regulation
CMGC_CDK_CDK4_CDK6_ST	Q08050	FOXM1	Q00534	CDK6	S692	V699I	699	Missense	distal	7	no	58.315	58.231	EPSD	COSMIC	54.510	Down-regulation
CMGC_CDK_CDK4_CDK6_ST	Q08050	FOXM1	Q00534	CDK6	S692	S686F	686	Missense	distal	-6	no	58.315	58.518	EPSD	COSMIC	54.510	Up-regulation
CMGC_CDK_CDK4_CDK6_ST	Q08050	FOXM1	Q00534	CDK6	S692	V687I	687	Missense	distal	-5	no	58.315	58.378	EPSD	COSMIC	54.510	Up-regulation
CMGC_CDK_CDK4_CDK6_ST	Q08050	FOXM1	Q00534	CDK6	S693	S695L	695	Missense	proximal	2	no	85.068	85.151	EPSD	COSMIC	54.510	Up-regulation
CMGC_CDK_CDK4_CDK6_ST	Q08050	FOXM1	Q00534	CDK6	S693	P688S	688	Missense	distal	-5	no	85.068	85.111	EPSD	COSMIC	54.510	Up-regulation
CMGC_CDK_CDK4_CDK6_ST	Q08050	FOXM1	Q00534	CDK6	S693	V699I	699	Missense	distal	6	no	85.068	85.057	EPSD	COSMIC	54.510	Down-regulation
CMGC_CDK_CDK4_CDK6_ST	Q08050	FOXM1	Q00534	CDK6	S693	S686F	686	Missense	distal	-7	no	85.068	84.301	EPSD	COSMIC	54.510	Down-regulation
CMGC_CDK_CDK4_CDK6_ST	Q08050	FOXM1	Q00534	CDK6	S693	V687I	687	Missense	distal	-6	no	85.068	85.104	EPSD	COSMIC	54.510	Up-regulation
CMGC_CDK_CDK4_CDK6_ST	Q08050	FOXM1	Q00534	CDK6	S704	V699I	699	Missense	distal	-5	no	87.020	87.082	EPSD;PhosphoSitePlus	COSMIC	54.510	Up-regulation
CMGC_CDK_CDK4_CDK6_ST	Q08050	FOXM1	Q00534	CDK6	S704	P707L	707	Missense	distal	3	no	87.020	84.844	EPSD;PhosphoSitePlus	COSMIC;GDSC	54.510	Down-regulation
CMGC_CDK_CDK4_CDK6_ST	P38936	CDKN1A	Q00534	CDK6	T57	D62Y	62	Missense	distal	5	no	84.771	84.860	EPSD	COSMIC	54.510	Up-regulation
CMGC_CDK_CDK4_CDK6_ST	P38936	CDKN1A	Q00534	CDK6	T57	D62H	62	Missense	distal	5	no	84.771	84.831	EPSD	COSMIC	54.510	Up-regulation
CMGC_CDK_CDK4_CDK6_ST	P38936	CDKN1A	Q00534	CDK6	T57	D52V	52	Missense	distal	-5	no	84.771	84.612	EPSD	COSMIC	54.510	Down-regulation
CMGC_CDK_CDK4_CDK6_ST	P38936	CDKN1A	Q00534	CDK6	T57	T57R	57	Missense	central	0	yes	84.771	0.000	EPSD	COSMIC	54.510	Loss
CMGC_CDK_CDK4_CDK6_ST	P38936	CDKN1A	Q00534	CDK6	S98	T97I	97	Missense	proximal	-1	no	84.272	84.233	EPSD	COSMIC	54.510	Down-regulation
CMGC_CDK_CDK4_CDK6_ST	P38936	CDKN1A	Q00534	CDK6	S130	E125Q	125	Missense	distal	-5	no	85.601	85.612	PhosphoSitePlus	COSMIC	54.510	Up-regulation
CMGC_CDK_CDK4_CDK6_ST	P38936	CDKN1A	Q00534	CDK6	S130	S137T	137	Missense	distal	7	no	85.601	85.387	PhosphoSitePlus	COSMIC	54.510	Down-regulation
CMGC_CDK_CDK4_CDK6_ST	P38936	CDKN1A	Q00534	CDK6	T145	D149N	149	Missense	distal	4	no	54.973	54.897	EPSD	COSMIC	54.510	Down-regulation
CMGC_CDK_CDK4_CDK6_ST	P38936	CDKN1A	Q00534	CDK6	T145	R143W	143	Missense	proximal	-2	no	54.973	54.954	EPSD	COSMIC;GDSC;CCLE	54.510	Down-regulation
CMGC_CDK_CDK4_CDK6_ST	P38936	CDKN1A	Q00534	CDK6	T145	Q138E	138	Missense	distal	-7	no	54.973	55.221	EPSD	COSMIC	54.510	Up-regulation
CMGC_CDK_CDK4_CDK6_ST	P38936	CDKN1A	Q00534	CDK6	T145	G139C	139	Missense	distal	-6	no	54.973	54.936	EPSD	COSMIC	54.510	Down-regulation
CMGC_CDK_CDK4_CDK6_ST	Q01196	RUNX1	Q00534	CDK6	T14	T14M	14	Missense	central	0	yes	87.305	0.000	EPSD	COSMIC	54.510	Loss
CMGC_CDK_CDK4_CDK6_ST	Q01196	RUNX1	Q00534	CDK6	S21	K24N	24	Missense	distal	3	no	84.268	83.244	EPSD	COSMIC	54.510	Down-regulation
CMGC_CDK_CDK4_CDK6_ST	Q01196	RUNX1	Q00534	CDK6	S21	M25K	25	Missense	distal	4	no	84.268	84.206	EPSD	COSMIC	54.510	Down-regulation
CMGC_CDK_CDK4_CDK6_ST	Q01196	RUNX1	Q00534	CDK6	S21	E27Q	27	Missense	distal	6	no	84.268	84.261	EPSD	COSMIC	54.510	Down-regulation
CMGC_CDK_CDK4_CDK6_ST	Q01196	RUNX1	Q00534	CDK6	S21	A28E	28	Missense	distal	7	no	84.268	84.281	EPSD	COSMIC	54.510	Up-regulation
CMGC_CDK_CDK4_CDK6_ST	Q01196	RUNX1	Q00534	CDK6	S21	P22L	22	Missense	proximal	1	no	84.268	-12.740	EPSD	COSMIC;CCLE	54.510	Loss
CMGC_CDK_CDK4_CDK6_ST	Q01196	RUNX1	Q00534	CDK6	S21	P22Q	22	Missense	proximal	1	no	84.268	1.975	EPSD	COSMIC	54.510	Loss
CMGC_CDK_CDK4_CDK6_ST	Q01196	RUNX1	Q00534	CDK6	S21	E27K	27	Missense	distal	6	no	84.268	84.284	EPSD	COSMIC	54.510	Up-regulation
CMGC_CDK_CDK4_CDK6_ST	Q01196	RUNX1	Q00534	CDK6	S21	T14M	14	Missense	distal	-7	no	84.268	83.689	EPSD	COSMIC	54.510	Down-regulation
CMGC_CDK_CDK4_CDK6_ST	Q01196	RUNX1	Q00534	CDK6	S67	L71M	71	Missense	distal	4	no	83.394	83.358	EPSD	COSMIC	54.510	Down-regulation
CMGC_CDK_CDK4_CDK6_ST	Q01196	RUNX1	Q00534	CDK6	S67	V63A	63	Missense	distal	-4	no	83.394	83.225	EPSD	COSMIC	54.510	Down-regulation
CMGC_CDK_CDK4_CDK6_ST	Q01196	RUNX1	Q00534	CDK6	S67	L62R	62	Missense	distal	-5	no	83.394	83.377	EPSD	COSMIC	54.510	Down-regulation
CMGC_CDK_CDK4_CDK6_ST	Q01196	RUNX1	Q00534	CDK6	S67	F70Y	70	Missense	distal	3	no	83.394	83.544	EPSD	COSMIC	54.510	Up-regulation
CMGC_CDK_CDK4_CDK6_ST	Q01196	RUNX1	Q00534	CDK6	S67	F70L	70	Missense	distal	3	no	83.394	83.376	EPSD	COSMIC	54.510	Down-regulation
CMGC_CDK_CDK4_CDK6_ST	Q01196	RUNX1	Q00534	CDK6	S67	T65A	65	Missense	proximal	-2	no	83.394	83.480	EPSD	COSMIC	54.510	Up-regulation
CMGC_CDK_CDK4_CDK6_ST	Q01196	RUNX1	Q00534	CDK6	S67	S73F	73	Missense	distal	6	no	83.394	83.343	EPSD	COSMIC	54.510	Down-regulation
CMGC_CDK_CDK4_CDK6_ST	Q01196	RUNX1	Q00534	CDK6	S67	D66N	66	Missense	proximal	-1	no	83.394	83.422	EPSD	COSMIC	54.510	Up-regulation
CMGC_CDK_CDK4_CDK6_ST	Q01196	RUNX1	Q00534	CDK6	S67	C72Y	72	Missense	distal	5	no	83.394	83.385	EPSD	COSMIC	54.510	Down-regulation
CMGC_CDK_CDK4_CDK6_ST	Q01196	RUNX1	Q00534	CDK6	S67	N69S	69	Missense	proximal	2	no	83.394	83.330	EPSD	COSMIC	54.510	Down-regulation
CMGC_CDK_CDK4_CDK6_ST	Q01196	RUNX1	Q00534	CDK6	S67	P68L	68	Missense	proximal	1	no	83.394	-13.614	EPSD	COSMIC	54.510	Loss
CMGC_CDK_CDK4_CDK6_ST	Q01196	RUNX1	Q00534	CDK6	S67	S67I	67	Missense	central	0	yes	83.394	0.000	EPSD	COSMIC	54.510	Loss
CMGC_CDK_CDK4_CDK6_ST	Q01196	RUNX1	Q00534	CDK6	S67	E61K	61	Missense	distal	-6	no	83.394	83.379	EPSD	COSMIC	54.510	Down-regulation
CMGC_CDK_CDK4_CDK6_ST	Q01196	RUNX1	Q00534	CDK6	S67	S67R	67	Missense	central	0	yes	83.394	0.000	EPSD	COSMIC;CCLE	54.510	Loss
CMGC_CDK_CDK4_CDK6_ST	Q01196	RUNX1	Q00534	CDK6	S67	S73C	73	Missense	distal	6	no	83.394	83.356	EPSD	COSMIC	54.510	Down-regulation
CMGC_CDK_CDK4_CDK6_ST	Q01196	RUNX1	Q00534	CDK6	S67	F70S	70	Missense	distal	3	no	83.394	85.886	EPSD	COSMIC	54.510	Up-regulation
CMGC_CDK_CDK4_CDK6_ST	Q01196	RUNX1	Q00534	CDK6	S67	D66Y	66	Missense	proximal	-1	no	83.394	83.415	EPSD	COSMIC	54.510	Up-regulation
CMGC_CDK_CDK4_CDK6_ST	Q01196	RUNX1	Q00534	CDK6	T84	L85P	85	Missense	proximal	1	no	-11.923	85.084	EPSD	COSMIC	54.510	Gain
CMGC_CDK_CDK4_CDK6_ST	Q01196	RUNX1	Q00534	CDK6	T147	L148P	148	Missense	proximal	1	no	-13.726	83.281	EPSD	COSMIC	54.510	Gain
CMGC_CDK_CDK4_CDK6_ST	Q01196	RUNX1	Q00534	CDK6	S193	F194S	194	Missense	proximal	1	no	-5.421	54.948	EPSD	COSMIC	54.510	Gain
CMGC_CDK_CDK4_CDK6_ST	Q01196	RUNX1	Q00534	CDK6	S212	A208G	208	Missense	distal	-4	no	83.867	83.827	EPSD	COSMIC	54.510	Down-regulation
CMGC_CDK_CDK4_CDK6_ST	Q01196	RUNX1	Q00534	CDK6	S212	S212L	212	Missense	central	0	yes	83.867	0.000	EPSD	COSMIC	54.510	Loss
CMGC_CDK_CDK4_CDK6_ST	Q01196	RUNX1	Q00534	CDK6	S212	R205Q	205	Missense	distal	-7	no	83.867	83.828	EPSD	COSMIC	54.510	Down-regulation
CMGC_CDK_CDK4_CDK6_ST	Q01196	RUNX1	Q00534	CDK6	S212	R205L	205	Missense	distal	-7	no	83.867	83.798	EPSD	COSMIC	54.510	Down-regulation
CMGC_CDK_CDK4_CDK6_ST	Q01196	RUNX1	Q00534	CDK6	S212	R210K	210	Missense	proximal	-2	no	83.867	83.805	EPSD	COSMIC	54.510	Down-regulation
CMGC_CDK_CDK4_CDK6_ST	Q01196	RUNX1	Q00534	CDK6	S212	T219M	219	Missense	distal	7	no	83.867	83.735	EPSD	COSMIC	54.510	Down-regulation
CMGC_CDK_CDK4_CDK6_ST	Q01196	RUNX1	Q00534	CDK6	S212	A208V	208	Missense	distal	-4	no	83.867	84.035	EPSD	COSMIC	54.510	Up-regulation
CMGC_CDK_CDK4_CDK6_ST	Q01196	RUNX1	Q00534	CDK6	S212	P218S	218	Missense	distal	6	no	83.867	83.855	EPSD	COSMIC	54.510	Down-regulation
CMGC_CDK_CDK4_CDK6_ST	Q01196	RUNX1	Q00534	CDK6	S212	P216L	216	Missense	distal	4	no	83.867	84.093	EPSD	COSMIC	54.510	Up-regulation
CMGC_CDK_CDK4_CDK6_ST	Q01196	RUNX1	Q00534	CDK6	S212	A208T	208	Missense	distal	-4	no	83.867	84.340	EPSD	COSMIC	54.510	Up-regulation
CMGC_CDK_CDK4_CDK6_ST	Q01196	RUNX1	Q00534	CDK6	S212	A217V	217	Missense	distal	5	no	83.867	83.923	EPSD	COSMIC	54.510	Up-regulation
CMGC_CDK_CDK4_CDK6_ST	Q01196	RUNX1	Q00534	CDK6	S212	R206H	206	Missense	distal	-6	no	83.867	83.865	EPSD	COSMIC	54.510	Down-regulation
CMGC_CDK_CDK4_CDK6_ST	Q01196	RUNX1	Q00534	CDK6	S212	P218L	218	Missense	distal	6	no	83.867	83.799	EPSD	COSMIC	54.510	Down-regulation
CMGC_CDK_CDK4_CDK6_ST	Q01196	RUNX1	Q00534	CDK6	S212	V211A	211	Missense	proximal	-1	no	83.867	83.849	EPSD	COSMIC	54.510	Down-regulation
CMGC_CDK_CDK4_CDK6_ST	Q01196	RUNX1	Q00534	CDK6	T219	L226F	226	Missense	distal	7	no	87.946	88.004	EPSD	COSMIC	54.510	Up-regulation
CMGC_CDK_CDK4_CDK6_ST	Q01196	RUNX1	Q00534	CDK6	T219	S212L	212	Missense	distal	-7	no	87.946	87.198	EPSD	COSMIC	54.510	Down-regulation
CMGC_CDK_CDK4_CDK6_ST	Q01196	RUNX1	Q00534	CDK6	T219	A224V	224	Missense	distal	5	no	87.946	88.002	EPSD	COSMIC	54.510	Up-regulation
CMGC_CDK_CDK4_CDK6_ST	Q01196	RUNX1	Q00534	CDK6	T219	R223C	223	Missense	distal	4	no	87.946	87.936	EPSD	COSMIC	54.510	Down-regulation
CMGC_CDK_CDK4_CDK6_ST	Q01196	RUNX1	Q00534	CDK6	T219	T219M	219	Missense	central	0	yes	87.946	0.000	EPSD	COSMIC	54.510	Loss
CMGC_CDK_CDK4_CDK6_ST	Q01196	RUNX1	Q00534	CDK6	T219	S225F	225	Missense	distal	6	no	87.946	87.896	EPSD	COSMIC	54.510	Down-regulation
CMGC_CDK_CDK4_CDK6_ST	Q01196	RUNX1	Q00534	CDK6	T219	P218S	218	Missense	proximal	-1	no	87.946	87.935	EPSD	COSMIC	54.510	Down-regulation
CMGC_CDK_CDK4_CDK6_ST	Q01196	RUNX1	Q00534	CDK6	T219	A224T	224	Missense	distal	5	no	87.946	88.076	EPSD	COSMIC	54.510	Up-regulation
CMGC_CDK_CDK4_CDK6_ST	Q01196	RUNX1	Q00534	CDK6	T219	P216L	216	Missense	distal	-3	no	87.946	88.167	EPSD	COSMIC	54.510	Up-regulation
CMGC_CDK_CDK4_CDK6_ST	Q01196	RUNX1	Q00534	CDK6	T219	A217V	217	Missense	proximal	-2	no	87.946	87.917	EPSD	COSMIC	54.510	Down-regulation
CMGC_CDK_CDK4_CDK6_ST	Q01196	RUNX1	Q00534	CDK6	T219	R223P	223	Missense	distal	4	no	87.946	87.729	EPSD	COSMIC	54.510	Down-regulation
CMGC_CDK_CDK4_CDK6_ST	Q01196	RUNX1	Q00534	CDK6	T219	P218L	218	Missense	proximal	-1	no	87.946	87.852	EPSD	COSMIC	54.510	Down-regulation
CMGC_CDK_CDK4_CDK6_ST	Q01196	RUNX1	Q00534	CDK6	T219	R223H	223	Missense	distal	4	no	87.946	87.956	EPSD	COSMIC	54.510	Up-regulation
CMGC_CDK_CDK4_CDK6_ST	Q01196	RUNX1	Q00534	CDK6	T219	P222S	222	Missense	distal	3	no	87.946	88.280	EPSD	COSMIC	54.510	Up-regulation
CMGC_CDK_CDK4_CDK6_ST	Q01196	RUNX1	Q00534	CDK6	S249	T243I	243	Missense	distal	-6	no	85.517	85.584	EPSD	COSMIC	54.510	Up-regulation
CMGC_CDK_CDK4_CDK6_ST	Q01196	RUNX1	Q00534	CDK6	S249	P250L	250	Missense	proximal	1	no	85.517	-11.490	EPSD	COSMIC	54.510	Loss
CMGC_CDK_CDK4_CDK6_ST	Q01196	RUNX1	Q00534	CDK6	S249	P251L	251	Missense	proximal	2	no	85.517	85.607	EPSD	COSMIC	54.510	Up-regulation
CMGC_CDK_CDK4_CDK6_ST	Q01196	RUNX1	Q00534	CDK6	S249	T243K	243	Missense	distal	-6	no	85.517	85.557	EPSD	COSMIC	54.510	Up-regulation
CMGC_CDK_CDK4_CDK6_ST	Q01196	RUNX1	Q00534	CDK6	S266	S268F	268	Missense	proximal	2	no	87.679	87.754	EPSD	COSMIC	54.510	Up-regulation
CMGC_CDK_CDK4_CDK6_ST	Q01196	RUNX1	Q00534	CDK6	S266	P267S	267	Missense	proximal	1	no	87.679	58.040	EPSD	COSMIC	54.510	Down-regulation
CMGC_CDK_CDK4_CDK6_ST	Q01196	RUNX1	Q00534	CDK6	S266	T273M	273	Missense	distal	7	no	87.679	87.546	EPSD	COSMIC	54.510	Down-regulation
CMGC_CDK_CDK4_CDK6_ST	Q01196	RUNX1	Q00534	CDK6	S266	G262R	262	Missense	distal	-4	no	87.679	87.559	EPSD	COSMIC	54.510	Down-regulation
CMGC_CDK_CDK4_CDK6_ST	Q01196	RUNX1	Q00534	CDK6	S266	P271Q	271	Missense	distal	5	no	87.679	87.303	EPSD	COSMIC	54.510	Down-regulation
CMGC_CDK_CDK4_CDK6_ST	Q01196	RUNX1	Q00534	CDK6	S266	Y260F	260	Missense	distal	-6	no	87.679	87.678	EPSD	COSMIC	54.510	Down-regulation
CMGC_CDK_CDK4_CDK6_ST	Q01196	RUNX1	Q00534	CDK6	S266	P271S	271	Missense	distal	5	no	87.679	87.612	EPSD	COSMIC	54.510	Down-regulation
CMGC_CDK_CDK4_CDK6_ST	Q01196	RUNX1	Q00534	CDK6	S266	A265S	265	Missense	proximal	-1	no	87.679	87.739	EPSD	COSMIC	54.510	Up-regulation
CMGC_CDK_CDK4_CDK6_ST	Q01196	RUNX1	Q00534	CDK6	S266	L261P	261	Missense	distal	-5	no	87.679	87.430	EPSD	COSMIC	54.510	Down-regulation
CMGC_CDK_CDK4_CDK6_ST	Q01196	RUNX1	Q00534	CDK6	S266	A272G	272	Missense	distal	6	no	87.679	87.663	EPSD	COSMIC	54.510	Down-regulation
CMGC_CDK_CDK4_CDK6_ST	Q01196	RUNX1	Q00534	CDK6	T273	P277L	277	Missense	distal	4	no	86.664	86.890	EPSD	COSMIC	54.510	Up-regulation
CMGC_CDK_CDK4_CDK6_ST	Q01196	RUNX1	Q00534	CDK6	T273	S268F	268	Missense	distal	-5	no	86.664	86.839	EPSD	COSMIC	54.510	Up-regulation
CMGC_CDK_CDK4_CDK6_ST	Q01196	RUNX1	Q00534	CDK6	T273	P267S	267	Missense	distal	-6	no	86.664	86.665	EPSD	COSMIC	54.510	Up-regulation
CMGC_CDK_CDK4_CDK6_ST	Q01196	RUNX1	Q00534	CDK6	T273	S276L	276	Missense	distal	3	no	86.664	84.155	EPSD	COSMIC	54.510	Down-regulation
CMGC_CDK_CDK4_CDK6_ST	Q01196	RUNX1	Q00534	CDK6	T273	T273M	273	Missense	central	0	yes	86.664	0.000	EPSD	COSMIC	54.510	Loss
CMGC_CDK_CDK4_CDK6_ST	Q01196	RUNX1	Q00534	CDK6	T273	P271Q	271	Missense	proximal	-2	no	86.664	86.868	EPSD	COSMIC	54.510	Up-regulation
CMGC_CDK_CDK4_CDK6_ST	Q01196	RUNX1	Q00534	CDK6	T273	P271S	271	Missense	proximal	-2	no	86.664	86.719	EPSD	COSMIC	54.510	Up-regulation
CMGC_CDK_CDK4_CDK6_ST	Q01196	RUNX1	Q00534	CDK6	T273	R279C	279	Missense	distal	6	no	86.664	86.679	EPSD	COSMIC	54.510	Up-regulation
CMGC_CDK_CDK4_CDK6_ST	Q01196	RUNX1	Q00534	CDK6	T273	A272G	272	Missense	proximal	-1	no	86.664	86.646	EPSD	COSMIC	54.510	Down-regulation
CMGC_CDK_CDK4_CDK6_ST	Q01196	RUNX1	Q00534	CDK6	T273	R279P	279	Missense	distal	6	no	86.664	86.729	EPSD	COSMIC	54.510	Up-regulation
CMGC_CDK_CDK4_CDK6_ST	Q01196	RUNX1	Q00534	CDK6	S276	P277L	277	Missense	proximal	1	no	86.145	-10.862	PhosphoSitePlus;EPSD	COSMIC	54.510	Loss
CMGC_CDK_CDK4_CDK6_ST	Q01196	RUNX1	Q00534	CDK6	S276	S276L	276	Missense	central	0	yes	86.145	0.000	PhosphoSitePlus;EPSD	COSMIC	54.510	Loss
CMGC_CDK_CDK4_CDK6_ST	Q01196	RUNX1	Q00534	CDK6	S276	T273M	273	Missense	distal	-3	no	86.145	86.236	PhosphoSitePlus;EPSD	COSMIC	54.510	Up-regulation
CMGC_CDK_CDK4_CDK6_ST	Q01196	RUNX1	Q00534	CDK6	S276	G282S	282	Missense	distal	6	no	86.145	86.199	PhosphoSitePlus;EPSD	COSMIC	54.510	Up-regulation
CMGC_CDK_CDK4_CDK6_ST	Q01196	RUNX1	Q00534	CDK6	S276	P271Q	271	Missense	distal	-5	no	86.145	86.331	PhosphoSitePlus;EPSD	COSMIC	54.510	Up-regulation
CMGC_CDK_CDK4_CDK6_ST	Q01196	RUNX1	Q00534	CDK6	S276	P271S	271	Missense	distal	-5	no	86.145	86.188	PhosphoSitePlus;EPSD	COSMIC	54.510	Up-regulation
CMGC_CDK_CDK4_CDK6_ST	Q01196	RUNX1	Q00534	CDK6	S276	R279C	279	Missense	distal	3	no	86.145	86.435	PhosphoSitePlus;EPSD	COSMIC	54.510	Up-regulation
CMGC_CDK_CDK4_CDK6_ST	Q01196	RUNX1	Q00534	CDK6	S276	A272G	272	Missense	distal	-4	no	86.145	86.105	PhosphoSitePlus;EPSD	COSMIC	54.510	Down-regulation
CMGC_CDK_CDK4_CDK6_ST	Q01196	RUNX1	Q00534	CDK6	S276	R279P	279	Missense	distal	3	no	86.145	88.260	PhosphoSitePlus;EPSD	COSMIC	54.510	Up-regulation
CMGC_CDK_CDK4_CDK6_ST	Q01196	RUNX1	Q00534	CDK6	S281	G282S	282	Missense	proximal	1	no	-1.565	60.111	EPSD	COSMIC	54.510	Gain
CMGC_CDK_CDK4_CDK6_ST	Q01196	RUNX1	Q00534	CDK6	S291	L294P	294	Missense	distal	3	no	54.191	56.366	EPSD	COSMIC	54.510	Gain
CMGC_CDK_CDK4_CDK6_ST	Q01196	RUNX1	Q00534	CDK6	S329	F326S	326	Missense	distal	-3	no	86.265	86.122	EPSD	COSMIC	54.510	Down-regulation
CMGC_CDK_CDK4_CDK6_ST	Q01196	RUNX1	Q00534	CDK6	S329	P332L	332	Missense	distal	3	no	86.265	84.089	EPSD	COSMIC	54.510	Down-regulation
CMGC_CDK_CDK4_CDK6_ST	Q01196	RUNX1	Q00534	CDK6	S329	S335L	335	Missense	distal	6	no	86.265	86.209	EPSD	COSMIC	54.510	Down-regulation
CMGC_CDK_CDK4_CDK6_ST	Q01196	RUNX1	Q00534	CDK6	T331	F326S	326	Missense	distal	-5	no	86.346	86.171	EPSD	COSMIC	54.510	Down-regulation
CMGC_CDK_CDK4_CDK6_ST	Q01196	RUNX1	Q00534	CDK6	T331	G338V	338	Missense	distal	7	no	86.346	86.506	EPSD	COSMIC	54.510	Up-regulation
CMGC_CDK_CDK4_CDK6_ST	Q01196	RUNX1	Q00534	CDK6	T331	P332L	332	Missense	proximal	1	no	86.346	-10.661	EPSD	COSMIC	54.510	Loss
CMGC_CDK_CDK4_CDK6_ST	Q01196	RUNX1	Q00534	CDK6	T331	S335L	335	Missense	distal	4	no	86.346	86.488	EPSD	COSMIC	54.510	Up-regulation
CMGC_CDK_CDK4_CDK6_ST	Q01196	RUNX1	Q00534	CDK6	T334	G340D	340	Missense	distal	6	no	57.023	57.007	EPSD	COSMIC	54.510	Down-regulation
CMGC_CDK_CDK4_CDK6_ST	Q01196	RUNX1	Q00534	CDK6	T334	M341L	341	Missense	distal	7	no	57.023	56.914	EPSD	COSMIC	54.510	Down-regulation
CMGC_CDK_CDK4_CDK6_ST	Q01196	RUNX1	Q00534	CDK6	T334	G338V	338	Missense	distal	4	no	57.023	56.938	EPSD	COSMIC	54.510	Down-regulation
CMGC_CDK_CDK4_CDK6_ST	Q01196	RUNX1	Q00534	CDK6	T334	P332L	332	Missense	proximal	-2	no	57.023	57.264	EPSD	COSMIC	54.510	Up-regulation
CMGC_CDK_CDK4_CDK6_ST	Q01196	RUNX1	Q00534	CDK6	T334	S335L	335	Missense	proximal	1	no	57.023	-10.345	EPSD	COSMIC	54.510	Loss
CMGC_CDK_CDK4_CDK6_ST	Q01196	RUNX1	Q00534	CDK6	S361	P356L	356	Missense	distal	-5	no	54.276	54.524	EPSD	COSMIC	54.510	Gain
CMGC_CDK_CDK4_CDK6_ST	Q01196	RUNX1	Q00534	CDK6	S361	A364V	364	Missense	distal	3	no	54.276	54.534	EPSD	COSMIC	54.510	Gain
CMGC_CDK_CDK4_CDK6_ST	Q01196	RUNX1	Q00534	CDK6	S372	G367D	367	Missense	distal	-5	no	58.563	58.600	EPSD	COSMIC	54.510	Up-regulation
CMGC_CDK_CDK4_CDK6_ST	Q01196	RUNX1	Q00534	CDK6	S372	S373L	373	Missense	proximal	1	no	58.563	-8.805	EPSD	COSMIC	54.510	Loss
CMGC_CDK_CDK4_CDK6_ST	Q01196	RUNX1	Q00534	CDK6	S372	Q370R	370	Missense	proximal	-2	no	58.563	58.582	EPSD	COSMIC	54.510	Up-regulation
CMGC_CDK_CDK4_CDK6_ST	Q01196	RUNX1	Q00534	CDK6	S372	P368M	368	Missense	distal	-4	no	58.563	57.645	EPSD	COSMIC	54.510	Down-regulation
CMGC_CDK_CDK4_CDK6_ST	Q01196	RUNX1	Q00534	CDK6	S372	Q365L	365	Missense	distal	-7	no	58.563	58.533	EPSD	COSMIC	54.510	Down-regulation
CMGC_CDK_CDK4_CDK6_ST	Q01196	RUNX1	Q00534	CDK6	S372	S375F	375	Missense	distal	3	no	58.563	56.071	EPSD	COSMIC	54.510	Down-regulation
CMGC_CDK_CDK4_CDK6_ST	Q01196	RUNX1	Q00534	CDK6	S372	G366A	366	Missense	distal	-6	no	58.563	58.503	EPSD	COSMIC	54.510	Down-regulation
CMGC_CDK_CDK4_CDK6_ST	Q01196	RUNX1	Q00534	CDK6	S372	F369I	369	Missense	distal	-3	no	58.563	58.527	EPSD	COSMIC	54.510	Down-regulation
CMGC_CDK_CDK4_CDK6_ST	Q01196	RUNX1	Q00534	CDK6	S372	P368L	368	Missense	distal	-4	no	58.563	57.494	EPSD	COSMIC	54.510	Down-regulation
CMGC_CDK_CDK4_CDK6_ST	Q01196	RUNX1	Q00534	CDK6	S373	G367D	367	Missense	distal	-6	no	83.178	83.198	EPSD	COSMIC	54.510	Up-regulation
CMGC_CDK_CDK4_CDK6_ST	Q01196	RUNX1	Q00534	CDK6	S373	S373L	373	Missense	central	0	yes	83.178	0.000	EPSD	COSMIC	54.510	Loss
CMGC_CDK_CDK4_CDK6_ST	Q01196	RUNX1	Q00534	CDK6	S373	Q370R	370	Missense	distal	-3	no	83.178	83.185	EPSD	COSMIC	54.510	Up-regulation
CMGC_CDK_CDK4_CDK6_ST	Q01196	RUNX1	Q00534	CDK6	S373	P368M	368	Missense	distal	-5	no	83.178	83.347	EPSD	COSMIC	54.510	Up-regulation
CMGC_CDK_CDK4_CDK6_ST	Q01196	RUNX1	Q00534	CDK6	S373	Y380C	380	Missense	distal	7	no	83.178	83.219	EPSD	COSMIC	54.510	Up-regulation
CMGC_CDK_CDK4_CDK6_ST	Q01196	RUNX1	Q00534	CDK6	S373	S375F	375	Missense	proximal	2	no	83.178	83.253	EPSD	COSMIC	54.510	Up-regulation
CMGC_CDK_CDK4_CDK6_ST	Q01196	RUNX1	Q00534	CDK6	S373	G366A	366	Missense	distal	-7	no	83.178	83.428	EPSD	COSMIC	54.510	Up-regulation
CMGC_CDK_CDK4_CDK6_ST	Q01196	RUNX1	Q00534	CDK6	S373	F369I	369	Missense	distal	-4	no	83.178	83.332	EPSD	COSMIC	54.510	Up-regulation
CMGC_CDK_CDK4_CDK6_ST	Q01196	RUNX1	Q00534	CDK6	S373	P368L	368	Missense	distal	-5	no	83.178	83.426	EPSD	COSMIC	54.510	Up-regulation
CMGC_CDK_CDK4_CDK6_ST	Q01196	RUNX1	Q00534	CDK6	S397	G393A	393	Missense	distal	-4	no	84.147	84.187	EPSD	COSMIC	54.510	Up-regulation
CMGC_CDK_CDK4_CDK6_ST	Q01196	RUNX1	Q00534	CDK6	S397	E395K	395	Missense	proximal	-2	no	84.147	84.128	EPSD	COSMIC	54.510	Down-regulation
CMGC_CDK_CDK4_CDK6_ST	Q01196	RUNX1	Q00534	CDK6	S397	V392G	392	Missense	distal	-5	no	84.147	84.269	EPSD	COSMIC	54.510	Up-regulation
CMGC_CDK_CDK4_CDK6_ST	Q01196	RUNX1	Q00534	CDK6	S397	S397L	397	Missense	central	0	yes	84.147	0.000	EPSD	COSMIC	54.510	Loss
CMGC_CDK_CDK4_CDK6_ST	Q01196	RUNX1	Q00534	CDK6	S397	P398Q	398	Missense	proximal	1	no	84.147	1.854	EPSD	COSMIC	54.510	Loss
CMGC_CDK_CDK4_CDK6_ST	Q01196	RUNX1	Q00534	CDK6	S397	P398L	398	Missense	proximal	1	no	84.147	-12.861	EPSD	COSMIC	54.510	Loss
CMGC_CDK_CDK4_CDK6_ST	Q01196	RUNX1	Q00534	CDK6	S397	R396H	396	Missense	proximal	-1	no	84.147	84.153	EPSD	COSMIC	54.510	Up-regulation
CMGC_CDK_CDK4_CDK6_ST	Q01196	RUNX1	Q00534	CDK6	S397	G394S	394	Missense	distal	-3	no	84.147	83.979	EPSD	COSMIC	54.510	Down-regulation
CMGC_CDK_CDK4_CDK6_ST	Q01196	RUNX1	Q00534	CDK6	S397	G393D	393	Missense	distal	-4	no	84.147	83.822	EPSD	COSMIC;CCLE	54.510	Down-regulation
CMGC_CDK_CDK4_CDK6_ST	Q01196	RUNX1	Q00534	CDK6	S397	R400H	400	Missense	distal	3	no	84.147	84.273	EPSD	COSMIC	54.510	Up-regulation
CMGC_CDK_CDK4_CDK6_ST	Q01196	RUNX1	Q00534	CDK6	S397	P399T	399	Missense	proximal	2	no	84.147	84.163	EPSD	COSMIC	54.510	Up-regulation
CMGC_CDK_CDK4_CDK6_ST	Q01196	RUNX1	Q00534	CDK6	S397	R396P	396	Missense	proximal	-1	no	84.147	84.236	EPSD	COSMIC	54.510	Up-regulation
CMGC_CDK_CDK4_CDK6_ST	Q01196	RUNX1	Q00534	CDK6	S397	S390F	390	Missense	distal	-7	no	84.147	83.380	EPSD	COSMIC	54.510	Down-regulation
CMGC_CDK_CDK4_CDK6_ST	Q01196	RUNX1	Q00534	CDK6	S397	S397P	397	Missense	central	0	yes	84.147	0.000	EPSD	COSMIC	54.510	Loss
CMGC_CDK_CDK4_CDK6_ST	Q01196	RUNX1	Q00534	CDK6	S397	R396C	396	Missense	proximal	-1	no	84.147	84.161	EPSD	COSMIC	54.510	Up-regulation
CMGC_CDK_CDK4_CDK6_ST	Q01196	RUNX1	Q00534	CDK6	S397	S397A	397	Missense	central	0	yes	84.147	0.000	EPSD	COSMIC	54.510	Loss
CMGC_CDK_CDK4_CDK6_ST	Q01196	RUNX1	Q00534	CDK6	T410	G411S	411	Missense	proximal	1	no	-6.017	55.660	EPSD	COSMIC	54.510	Gain
CMGC_CDK_CDK4_CDK6_ST	Q01196	RUNX1	Q00534	CDK6	S435	E429D	429	Missense	distal	-6	no	84.350	84.435	EPSD	COSMIC	54.510	Up-regulation
CMGC_CDK_CDK4_CDK6_ST	Q01196	RUNX1	Q00534	CDK6	S435	A440V	440	Missense	distal	5	no	84.350	84.406	EPSD	COSMIC	54.510	Up-regulation
CMGC_CDK_CDK4_CDK6_ST	Q01196	RUNX1	Q00534	CDK6	S435	S433N	433	Missense	proximal	-2	no	84.350	84.493	EPSD	COSMIC	54.510	Up-regulation
CMGC_CDK_CDK4_CDK6_ST	Q01196	RUNX1	Q00534	CDK6	S435	P436C	436	Missense	proximal	1	no	84.350	-2.777	EPSD	COSMIC	54.510	Loss
CMGC_CDK_CDK4_CDK6_ST	Q01196	RUNX1	Q00534	CDK6	S435	S442F	442	Missense	distal	7	no	84.350	83.951	EPSD	COSMIC	54.510	Down-regulation
CMGC_CDK_CDK4_CDK6_ST	Q01196	RUNX1	Q00534	CDK6	S435	E429K	429	Missense	distal	-6	no	84.350	84.335	EPSD	COSMIC	54.510	Down-regulation
CMGC_CDK_CDK4_CDK6_ST	Q01196	RUNX1	Q00534	CDK6	S435	S431G	431	Missense	distal	-4	no	84.350	83.997	EPSD	COSMIC	54.510	Down-regulation
CMGC_CDK_CDK4_CDK6_ST	Q01196	RUNX1	Q00534	CDK6	S435	M439L	439	Missense	distal	4	no	84.350	84.385	EPSD	COSMIC;CCLE	54.510	Up-regulation
CMGC_CDK_CDK4_CDK6_ST	Q01196	RUNX1	Q00534	CDK6	S435	M439T	439	Missense	distal	4	no	84.350	84.231	EPSD	COSMIC	54.510	Down-regulation
CMGC_CDK_CDK4_CDK6_ST	Q96KS0	EGLN2	Q00534	CDK6	S74	G79S	79	Missense	distal	5	no	84.198	84.526	EPSD	COSMIC	54.510	Up-regulation
CMGC_CDK_CDK4_CDK6_ST	Q96KS0	EGLN2	Q00534	CDK6	S130	A128D	128	Missense	proximal	-2	no	85.564	85.633	PhosphoSitePlus	COSMIC	54.510	Up-regulation
CMGC_CDK_CDK4_CDK6_ST	Q96KS0	EGLN2	Q00534	CDK6	S130	P129L	129	Missense	proximal	-1	no	85.564	85.470	PhosphoSitePlus	COSMIC	54.510	Down-regulation
CMGC_CDK_CDK4_CDK6_ST	Q96KS0	EGLN2	Q00534	CDK6	S155	M150I	150	Missense	distal	-5	no	57.175	57.190	EPSD	COSMIC	54.510	Up-regulation
CMGC_CDK_CDK4_CDK6_ST	Q96KS0	EGLN2	Q00534	CDK6	T405	P403Q	403	Missense	proximal	-2	no	82.582	82.786	EPSD	COSMIC	54.510	Up-regulation
CMGC_CDK_CDK4_CDK6_ST	Q96KS0	EGLN2	Q00534	CDK6	T405	T405M	405	Missense	central	0	yes	82.582	0.000	EPSD	COSMIC;GDSC	54.510	Loss
CMGC_CDK_CDK4_CDK6_ST	P14618	PKM	Q00534	CDK6	S37	R32L	32	Missense	distal	-5	no	85.695	85.712	PhosphoSitePlus	COSMIC	54.510	Up-regulation
CMGC_CDK_CDK4_CDK6_ST	P14618	PKM	Q00534	CDK6	T80	H81P	81	Missense	proximal	1	no	-7.604	85.521	EPSD	COSMIC	54.510	Gain
CMGC_CDK_CDK4_CDK6_ST	P14618	PKM	Q00534	CDK6	T405	P403T	403	Missense	proximal	-2	no	56.058	56.161	EPSD	COSMIC	54.510	Up-regulation
CMGC_CDK_CDK4_CDK6_ST	P14618	PKM	Q00534	CDK6	T405	D407N	407	Missense	proximal	2	no	56.058	56.025	EPSD	COSMIC	54.510	Down-regulation
CMGC_CDK_CDK4_CDK6_ST	P14618	PKM	Q00534	CDK6	T405	D407H	407	Missense	proximal	2	no	56.058	56.039	EPSD	COSMIC	54.510	Down-regulation
CMGC_CDK_CDK4_CDK6_ST	P14618	PKM	Q00534	CDK6	T405	R400H	400	Missense	distal	-5	no	56.058	56.041	EPSD	COSMIC	54.510	Down-regulation
CMGC_CDK_CDK4_CDK6_ST	P14618	PKM	Q00534	CDK6	T405	T409A	409	Missense	distal	4	no	56.058	56.175	EPSD	COSMIC	54.510	Up-regulation
CMGC_CDK_CDK4_CDK6_ST	P14618	PKM	Q00534	CDK6	T405	L398H	398	Missense	distal	-7	no	56.058	56.024	EPSD	COSMIC	54.510	Down-regulation
CMGC_CDK_CDK4_CDK6_ST	P21333	FLNA	Q00534	CDK6	S368	A361T	361	Missense	distal	-7	no	83.507	84.079	EPSD	COSMIC	54.510	Up-regulation
CMGC_CDK_CDK4_CDK6_ST	P21333	FLNA	Q00534	CDK6	S368	V372L	372	Missense	distal	4	no	83.507	83.577	EPSD	COSMIC	54.510	Up-regulation
CMGC_CDK_CDK4_CDK6_ST	P21333	FLNA	Q00534	CDK6	S468	Y470C	470	Missense	proximal	2	no	84.390	84.378	EPSD	COSMIC	54.510	Down-regulation
CMGC_CDK_CDK4_CDK6_ST	P21333	FLNA	Q00534	CDK6	S468	G462D	462	Missense	distal	-6	no	84.390	84.411	EPSD	COSMIC	54.510	Up-regulation
CMGC_CDK_CDK4_CDK6_ST	P21333	FLNA	Q00534	CDK6	S564	R563C	563	Missense	proximal	-1	no	84.560	84.574	EPSD	COSMIC;GDSC;CCLE	54.510	Up-regulation
CMGC_CDK_CDK4_CDK6_ST	P21333	FLNA	Q00534	CDK6	S564	E567G	567	Missense	distal	3	no	84.560	84.060	EPSD	COSMIC	54.510	Down-regulation
CMGC_CDK_CDK4_CDK6_ST	P21333	FLNA	Q00534	CDK6	S564	R563H	563	Missense	proximal	-1	no	84.560	84.566	EPSD	COSMIC	54.510	Up-regulation
CMGC_CDK_CDK4_CDK6_ST	P21333	FLNA	Q00534	CDK6	S564	S564C	564	Missense	central	0	yes	84.560	0.000	EPSD	COSMIC	54.510	Loss
CMGC_CDK_CDK4_CDK6_ST	P21333	FLNA	Q00534	CDK6	S564	G562R	562	Missense	proximal	-2	no	84.560	84.542	EPSD	COSMIC	54.510	Down-regulation
CMGC_CDK_CDK4_CDK6_ST	P21333	FLNA	Q00534	CDK6	S564	G562S	562	Missense	proximal	-2	no	84.560	84.373	EPSD	COSMIC	54.510	Down-regulation
CMGC_CDK_CDK4_CDK6_ST	P21333	FLNA	Q00534	CDK6	S657	M660I	660	Missense	distal	3	no	81.950	82.152	EPSD	COSMIC	54.510	Up-regulation
CMGC_CDK_CDK4_CDK6_ST	P21333	FLNA	Q00534	CDK6	S757	V752A	752	Missense	distal	-5	no	84.185	84.233	EPSD	COSMIC	54.510	Up-regulation
CMGC_CDK_CDK4_CDK6_ST	P21333	FLNA	Q00534	CDK6	S757	V752I	752	Missense	distal	-5	no	84.185	84.248	EPSD	COSMIC	54.510	Up-regulation
CMGC_CDK_CDK4_CDK6_ST	P21333	FLNA	Q00534	CDK6	S757	G751V	751	Missense	distal	-6	no	84.185	84.097	EPSD	COSMIC	54.510	Down-regulation
CMGC_CDK_CDK4_CDK6_ST	P21333	FLNA	Q00534	CDK6	T857	S860N	860	Missense	distal	3	no	87.210	84.913	EPSD	COSMIC	54.510	Down-regulation
CMGC_CDK_CDK4_CDK6_ST	P21333	FLNA	Q00534	CDK6	S860	S860N	860	Missense	central	0	yes	83.018	0.000	EPSD	COSMIC	54.510	Loss
CMGC_CDK_CDK4_CDK6_ST	P21333	FLNA	Q00534	CDK6	T938	T938M	938	Missense	central	0	yes	83.439	0.000	EPSD	COSMIC	54.510	Loss
CMGC_CDK_CDK4_CDK6_ST	P21333	FLNA	Q00534	CDK6	T938	Y933H	933	Missense	distal	-5	no	83.439	83.424	EPSD	COSMIC;CCLE	54.510	Down-regulation
CMGC_CDK_CDK4_CDK6_ST	P21333	FLNA	Q00534	CDK6	S959	S959R	959	Missense	central	0	yes	86.374	0.000	EPSD	COSMIC	54.510	Loss
CMGC_CDK_CDK4_CDK6_ST	P21333	FLNA	Q00534	CDK6	S966	S959R	959	Missense	distal	-7	no	84.931	84.251	EPSD	COSMIC	54.510	Down-regulation
CMGC_CDK_CDK4_CDK6_ST	P21333	FLNA	Q00534	CDK6	S1055	G1054A	1054	Missense	proximal	-1	no	86.895	86.913	EPSD	COSMIC	54.510	Up-regulation
CMGC_CDK_CDK4_CDK6_ST	P21333	FLNA	Q00534	CDK6	S1055	P1058S	1058	Missense	distal	3	no	86.895	87.229	EPSD	COSMIC	54.510	Up-regulation
CMGC_CDK_CDK4_CDK6_ST	P21333	FLNA	Q00534	CDK6	S1084	A1086T	1086	Missense	proximal	2	no	83.347	83.298	EPSD	COSMIC;CCLE	54.510	Down-regulation
CMGC_CDK_CDK4_CDK6_ST	P21333	FLNA	Q00534	CDK6	S1084	R1087C	1087	Missense	distal	3	no	83.347	83.637	EPSD	COSMIC;GDSC	54.510	Up-regulation
CMGC_CDK_CDK4_CDK6_ST	P21333	FLNA	Q00534	CDK6	T1255	A1252G	1252	Missense	distal	-3	no	55.305	55.368	EPSD	COSMIC	54.510	Up-regulation
CMGC_CDK_CDK4_CDK6_ST	P21333	FLNA	Q00534	CDK6	T1322	Y1324C	1324	Missense	proximal	2	no	84.151	84.139	EPSD	COSMIC	54.510	Down-regulation
CMGC_CDK_CDK4_CDK6_ST	P21333	FLNA	Q00534	CDK6	T1322	M1316T	1316	Missense	distal	-6	no	84.151	84.079	EPSD	COSMIC;GDSC;CCLE	54.510	Down-regulation
CMGC_CDK_CDK4_CDK6_ST	P21333	FLNA	Q00534	CDK6	S1436	P1441S	1441	Missense	distal	5	no	85.444	85.378	EPSD	COSMIC	54.510	Down-regulation
CMGC_CDK_CDK4_CDK6_ST	P21333	FLNA	Q00534	CDK6	S1459	S1459R	1459	Missense	central	0	yes	84.005	0.000	EPSD;PhosphoSitePlus	COSMIC	54.510	Loss
CMGC_CDK_CDK4_CDK6_ST	P21333	FLNA	Q00534	CDK6	S1459	G1457S	1457	Missense	proximal	-2	no	84.005	83.818	EPSD;PhosphoSitePlus	COSMIC	54.510	Down-regulation
CMGC_CDK_CDK4_CDK6_ST	P21333	FLNA	Q00534	CDK6	S1459	G1455R	1455	Missense	distal	-4	no	84.005	83.885	EPSD;PhosphoSitePlus	COSMIC;CCLE	54.510	Down-regulation
CMGC_CDK_CDK4_CDK6_ST	P21333	FLNA	Q00534	CDK6	T1475	Q1469E	1469	Missense	distal	-6	no	54.962	54.923	EPSD	COSMIC	54.510	Down-regulation
CMGC_CDK_CDK4_CDK6_ST	P21333	FLNA	Q00534	CDK6	T1475	P1468S	1468	Missense	distal	-7	no	54.962	54.564	EPSD	COSMIC;GDSC;CCLE	54.510	Down-regulation
CMGC_CDK_CDK4_CDK6_ST	P21333	FLNA	Q00534	CDK6	S1533	V1539M	1539	Missense	distal	6	no	85.451	85.438	EPSD	COSMIC	54.510	Down-regulation
CMGC_CDK_CDK4_CDK6_ST	P21333	FLNA	Q00534	CDK6	S1533	V1539A	1539	Missense	distal	6	no	85.451	85.437	EPSD	COSMIC	54.510	Down-regulation
CMGC_CDK_CDK4_CDK6_ST	P21333	FLNA	Q00534	CDK6	S1734	P1732T	1732	Missense	proximal	-2	no	84.001	84.104	EPSD	COSMIC	54.510	Up-regulation
CMGC_CDK_CDK4_CDK6_ST	P21333	FLNA	Q00534	CDK6	S1734	P1732S	1732	Missense	proximal	-2	no	84.001	84.055	EPSD	COSMIC	54.510	Up-regulation
CMGC_CDK_CDK4_CDK6_ST	P21333	FLNA	Q00534	CDK6	S1854	P1852Q	1852	Missense	proximal	-2	no	82.296	82.500	EPSD	COSMIC	54.510	Up-regulation
CMGC_CDK_CDK4_CDK6_ST	P21333	FLNA	Q00534	CDK6	S1854	S1854R	1854	Missense	central	0	yes	82.296	0.000	EPSD	COSMIC	54.510	Loss
CMGC_CDK_CDK4_CDK6_ST	P21333	FLNA	Q00534	CDK6	S1946	R1951H	1951	Missense	distal	5	no	83.946	83.922	EPSD	COSMIC	54.510	Down-regulation
CMGC_CDK_CDK4_CDK6_ST	P21333	FLNA	Q00534	CDK6	S1946	A1950S	1950	Missense	distal	4	no	83.946	83.842	EPSD	COSMIC	54.510	Down-regulation
CMGC_CDK_CDK4_CDK6_ST	P21333	FLNA	Q00534	CDK6	S1946	G1945C	1945	Missense	proximal	-1	no	83.946	83.961	EPSD	COSMIC	54.510	Up-regulation
CMGC_CDK_CDK4_CDK6_ST	P21333	FLNA	Q00534	CDK6	S1946	R1951W	1951	Missense	distal	5	no	83.946	83.967	EPSD	COSMIC	54.510	Up-regulation
CMGC_CDK_CDK4_CDK6_ST	P21333	FLNA	Q00534	CDK6	S1967	A1968P	1968	Missense	proximal	1	no	2.817	83.452	EPSD	COSMIC	54.510	Gain
CMGC_CDK_CDK4_CDK6_ST	P21333	FLNA	Q00534	CDK6	S2032	G2027A	2027	Missense	distal	-5	no	54.592	54.517	EPSD	COSMIC	54.510	Down-regulation
CMGC_CDK_CDK4_CDK6_ST	P21333	FLNA	Q00534	CDK6	S2032	P2036Q	2036	Missense	distal	4	no	54.592	54.808	EPSD	COSMIC	54.510	Up-regulation
CMGC_CDK_CDK4_CDK6_ST	P21333	FLNA	Q00534	CDK6	S2032	A2031V	2031	Missense	proximal	-1	no	54.592	54.609	EPSD	COSMIC	54.510	Up-regulation
CMGC_CDK_CDK4_CDK6_ST	P21333	FLNA	Q00534	CDK6	S2032	G2027V	2027	Missense	distal	-5	no	54.592	54.469	EPSD	COSMIC	54.510	Loss
CMGC_CDK_CDK4_CDK6_ST	P21333	FLNA	Q00534	CDK6	S2033	G2027A	2027	Missense	distal	-6	no	85.700	85.640	EPSD	COSMIC	54.510	Down-regulation
CMGC_CDK_CDK4_CDK6_ST	P21333	FLNA	Q00534	CDK6	S2033	P2036Q	2036	Missense	distal	3	no	85.700	83.528	EPSD	COSMIC	54.510	Down-regulation
CMGC_CDK_CDK4_CDK6_ST	P21333	FLNA	Q00534	CDK6	S2033	A2031V	2031	Missense	proximal	-2	no	85.700	85.670	EPSD	COSMIC	54.510	Down-regulation
CMGC_CDK_CDK4_CDK6_ST	P21333	FLNA	Q00534	CDK6	S2033	S2040R	2040	Missense	distal	7	no	85.700	85.283	EPSD	COSMIC	54.510	Down-regulation
CMGC_CDK_CDK4_CDK6_ST	P21333	FLNA	Q00534	CDK6	S2033	S2040L	2040	Missense	distal	7	no	85.700	85.243	EPSD	COSMIC	54.510	Down-regulation
CMGC_CDK_CDK4_CDK6_ST	P21333	FLNA	Q00534	CDK6	S2033	G2027V	2027	Missense	distal	-6	no	85.700	85.612	EPSD	COSMIC	54.510	Down-regulation
CMGC_CDK_CDK4_CDK6_ST	P21333	FLNA	Q00534	CDK6	S2128	F2130L	2130	Missense	proximal	2	no	86.695	86.703	EPSD	COSMIC	54.510	Up-regulation
CMGC_CDK_CDK4_CDK6_ST	P21333	FLNA	Q00534	CDK6	S2128	D2122N	2122	Missense	distal	-6	no	86.695	86.633	EPSD	COSMIC	54.510	Down-regulation
CMGC_CDK_CDK4_CDK6_ST	P21333	FLNA	Q00534	CDK6	T2179	G2183A	2183	Missense	distal	4	no	56.659	56.607	EPSD	COSMIC	54.510	Down-regulation
CMGC_CDK_CDK4_CDK6_ST	P21333	FLNA	Q00534	CDK6	T2179	S2182L	2182	Missense	distal	3	no	56.659	54.150	EPSD	COSMIC	54.510	Loss
CMGC_CDK_CDK4_CDK6_ST	P21333	FLNA	Q00534	CDK6	T2179	K2184R	2184	Missense	distal	5	no	56.659	56.573	EPSD	COSMIC	54.510	Down-regulation
CMGC_CDK_CDK4_CDK6_ST	P21333	FLNA	Q00534	CDK6	S2180	G2183A	2183	Missense	distal	3	no	83.045	83.572	EPSD	COSMIC	54.510	Up-regulation
CMGC_CDK_CDK4_CDK6_ST	P21333	FLNA	Q00534	CDK6	S2180	S2182L	2182	Missense	proximal	2	no	83.045	83.128	EPSD	COSMIC	54.510	Up-regulation
CMGC_CDK_CDK4_CDK6_ST	P21333	FLNA	Q00534	CDK6	S2180	K2184R	2184	Missense	distal	4	no	83.045	83.134	EPSD	COSMIC	54.510	Up-regulation
CMGC_CDK_CDK4_CDK6_ST	P21333	FLNA	Q00534	CDK6	S2224	G2218D	2218	Missense	distal	-6	no	83.999	84.019	EPSD	COSMIC;GDSC;CCLE	54.510	Up-regulation
CMGC_CDK_CDK4_CDK6_ST	P21333	FLNA	Q00534	CDK6	S2224	G2223W	2223	Missense	proximal	-1	no	83.999	84.014	EPSD	COSMIC	54.510	Up-regulation
CMGC_CDK_CDK4_CDK6_ST	P21333	FLNA	Q00534	CDK6	S2319	P2320T	2320	Missense	proximal	1	no	85.345	16.737	EPSD	COSMIC	54.510	Loss
CMGC_CDK_CDK4_CDK6_ST	P21333	FLNA	Q00534	CDK6	S2327	P2320T	2320	Missense	distal	-7	no	84.700	84.305	EPSD	COSMIC	54.510	Down-regulation
CMGC_CDK_CDK4_CDK6_ST	P21333	FLNA	Q00534	CDK6	S2338	V2337F	2337	Missense	proximal	-1	no	56.455	56.424	EPSD	COSMIC	54.510	Down-regulation
CMGC_CDK_CDK4_CDK6_ST	P21333	FLNA	Q00534	CDK6	S2338	G2344W	2344	Missense	distal	6	no	56.455	56.467	EPSD	COSMIC	54.510	Up-regulation
CMGC_CDK_CDK4_CDK6_ST	P21333	FLNA	Q00534	CDK6	S2338	V2337I	2337	Missense	proximal	-1	no	56.455	56.438	EPSD	COSMIC	54.510	Down-regulation
CMGC_CDK_CDK4_CDK6_ST	P21333	FLNA	Q00534	CDK6	S2338	S2343N	2343	Missense	distal	5	no	56.455	56.158	EPSD	COSMIC	54.510	Down-regulation
CMGC_CDK_CDK4_CDK6_ST	P21333	FLNA	Q00534	CDK6	S2370	D2365N	2365	Missense	distal	-5	no	81.913	81.811	EPSD	COSMIC	54.510	Down-regulation
CMGC_CDK_CDK4_CDK6_ST	P21333	FLNA	Q00534	CDK6	S2370	S2370N	2370	Missense	central	0	yes	81.913	0.000	EPSD	COSMIC	54.510	Loss
CMGC_CDK_CDK4_CDK6_ST	P21333	FLNA	Q00534	CDK6	S2414	P2415R	2415	Missense	proximal	1	no	83.173	-7.037	EPSD	COSMIC	54.510	Loss
CMGC_CDK_CDK4_CDK6_ST	P21333	FLNA	Q00534	CDK6	S2414	V2420F	2420	Missense	distal	6	no	83.173	83.147	EPSD	COSMIC	54.510	Down-regulation
CMGC_CDK_CDK4_CDK6_ST	P21333	FLNA	Q00534	CDK6	S2414	G2408S	2408	Missense	distal	-6	no	83.173	82.948	EPSD	COSMIC	54.510	Down-regulation
CMGC_CDK_CDK4_CDK6_ST	P21333	FLNA	Q00534	CDK6	S2414	G2413E	2413	Missense	proximal	-1	no	83.173	83.192	EPSD	COSMIC	54.510	Up-regulation
CMGC_CDK_CDK4_CDK6_ST	P21333	FLNA	Q00534	CDK6	T2488	R2484C	2484	Missense	distal	-4	no	84.315	84.396	EPSD	COSMIC	54.510	Up-regulation
CMGC_CDK_CDK4_CDK6_ST	P21333	FLNA	Q00534	CDK6	T2488	E2481D	2481	Missense	distal	-7	no	84.315	83.831	EPSD	COSMIC	54.510	Down-regulation
CMGC_CDK_CDK4_CDK6_ST	P21333	FLNA	Q00534	CDK6	T2488	R2484S	2484	Missense	distal	-4	no	84.315	84.788	EPSD	COSMIC	54.510	Up-regulation
CMGC_CDK_CDK4_CDK6_ST	P21333	FLNA	Q00534	CDK6	T2488	Y2483C	2483	Missense	distal	-5	no	84.315	84.272	EPSD	COSMIC	54.510	Down-regulation
CMGC_CDK_CDK4_CDK6_ST	P21333	FLNA	Q00534	CDK6	S2510	P2511L	2511	Missense	proximal	1	no	86.373	-10.635	EPSD	COSMIC	54.510	Loss
CMGC_CDK_CDK4_CDK6_ST	P21333	FLNA	Q00534	CDK6	S2510	S2510F	2510	Missense	central	0	yes	86.373	0.000	EPSD	COSMIC	54.510	Loss
CMGC_CDK_CDK4_CDK6_ST	P21333	FLNA	Q00534	CDK6	T2530	H2528Q	2528	Missense	proximal	-2	no	56.717	56.694	EPSD	COSMIC	54.510	Down-regulation
CMGC_CDK_CDK4_CDK6_ST	P21333	FLNA	Q00534	CDK6	T2530	H2525P	2525	Missense	distal	-5	no	56.717	56.503	EPSD	COSMIC	54.510	Down-regulation
CMGC_CDK_CDK4_CDK6_ST	P21333	FLNA	Q00534	CDK6	T2530	S2532L	2532	Missense	proximal	2	no	56.717	56.800	EPSD	COSMIC	54.510	Up-regulation
CMGC_CDK_CDK4_CDK6_ST	P21333	FLNA	Q00534	CDK6	T2530	V2533A	2533	Missense	distal	3	no	56.717	56.459	EPSD	COSMIC	54.510	Down-regulation
CMGC_CDK_CDK4_CDK6_ST	P21333	FLNA	Q00534	CDK6	T2530	S2531R	2531	Missense	proximal	1	no	56.717	-3.854	EPSD	COSMIC	54.510	Loss
CMGC_CDK_CDK4_CDK6_ST	P21333	FLNA	Q00534	CDK6	S2576	D2581H	2581	Missense	distal	5	no	55.265	55.325	EPSD	COSMIC;GDSC	54.510	Up-regulation
CMGC_CDK_CDK4_CDK6_ST	P21333	FLNA	Q00534	CDK6	S2576	V2572I	2572	Missense	distal	-4	no	55.265	55.044	EPSD	COSMIC;GDSC;CCLE	54.510	Down-regulation
CMGC_CDK_CDK4_CDK6_ST	P21333	FLNA	Q00534	CDK6	T2599	G2596S	2596	Missense	distal	-3	no	83.572	83.404	EPSD	COSMIC	54.510	Down-regulation
CMGC_CDK_CDK4_CDK6_ST	P21333	FLNA	Q00534	CDK6	T2599	G2593V	2593	Missense	distal	-6	no	83.572	83.484	EPSD	COSMIC	54.510	Down-regulation
CMGC_CDK_CDK4_CDK6_ST	P21333	FLNA	Q00534	CDK6	T2599	V2606L	2606	Missense	distal	7	no	83.572	83.371	EPSD	COSMIC	54.510	Down-regulation
CMGC_CDK_CDK4_CDK6_ST	P21333	FLNA	Q00534	CDK6	S2640	P2641L	2641	Missense	proximal	1	no	82.692	-14.316	EPSD	COSMIC	54.510	Loss
CMGC_CDK_CDK4_CDK6_ST	P21333	FLNA	Q00534	CDK6	S2640	R2643C	2643	Missense	distal	3	no	82.692	82.982	EPSD	COSMIC	54.510	Up-regulation
CMGC_CDK_CDK4_CDK6_ST	P46527	CDKN1B	Q00534	CDK6	S10	R5L	5	Missense	distal	-5	no	83.673	83.690	PhosphoSitePlus;EPSD	COSMIC	54.510	Up-regulation
CMGC_CDK_CDK4_CDK6_ST	P46527	CDKN1B	Q00534	CDK6	S10	E14K	14	Missense	distal	4	no	83.673	83.620	PhosphoSitePlus;EPSD	COSMIC	54.510	Down-regulation
CMGC_CDK_CDK4_CDK6_ST	P46527	CDKN1B	Q00534	CDK6	S10	M16T	16	Missense	distal	6	no	83.673	83.720	PhosphoSitePlus;EPSD	COSMIC	54.510	Up-regulation
CMGC_CDK_CDK4_CDK6_ST	P46527	CDKN1B	Q00534	CDK6	S10	N3D	3	Missense	distal	-7	no	83.673	83.326	PhosphoSitePlus;EPSD	COSMIC	54.510	Down-regulation
CMGC_CDK_CDK4_CDK6_ST	P46527	CDKN1B	Q00534	CDK6	S10	P11S	11	Missense	proximal	1	no	83.673	54.034	PhosphoSitePlus;EPSD	COSMIC	54.510	Loss
CMGC_CDK_CDK4_CDK6_ST	P46527	CDKN1B	Q00534	CDK6	S10	S12N	12	Missense	proximal	2	no	83.673	83.736	PhosphoSitePlus;EPSD	COSMIC	54.510	Up-regulation
CMGC_CDK_CDK4_CDK6_ST	P46527	CDKN1B	Q00534	CDK6	S10	D17E	17	Missense	distal	7	no	83.673	83.841	PhosphoSitePlus;EPSD	COSMIC	54.510	Up-regulation
CMGC_CDK_CDK4_CDK6_ST	P46527	CDKN1B	Q00534	CDK6	S178	V184L	184	Missense	distal	6	no	83.718	83.686	EPSD	COSMIC	54.510	Down-regulation
CMGC_CDK_CDK4_CDK6_ST	P46527	CDKN1B	Q00534	CDK6	S178	G182D	182	Missense	distal	4	no	83.718	83.750	EPSD	COSMIC	54.510	Up-regulation
CMGC_CDK_CDK4_CDK6_ST	P46527	CDKN1B	Q00534	CDK6	T187	V184L	184	Missense	distal	-3	no	84.707	84.779	EPSD;PhosphoSitePlus	COSMIC	54.510	Up-regulation
CMGC_CDK_CDK4_CDK6_ST	P46527	CDKN1B	Q00534	CDK6	T187	G182D	182	Missense	distal	-5	no	84.707	84.743	EPSD;PhosphoSitePlus	COSMIC	54.510	Up-regulation
CMGC_CDK_CDK4_CDK6_ST	P46527	CDKN1B	Q00534	CDK6	T187	R194K	194	Missense	distal	7	no	84.707	84.800	EPSD;PhosphoSitePlus	COSMIC	54.510	Up-regulation
CMGC_CDK_CDK4_CDK6_ST	Q92879	CELF1	Q00534	CDK6	S129	S130L	130	Missense	proximal	1	no	55.007	-12.361	EPSD	COSMIC	54.510	Loss
CMGC_CDK_CDK4_CDK6_ST	Q92879	CELF1	Q00534	CDK6	S129	S129L	129	Missense	central	0	yes	55.007	0.000	EPSD	COSMIC	54.510	Loss
CMGC_CDK_CDK4_CDK6_ST	Q92879	CELF1	Q00534	CDK6	S179	Q172H	172	Missense	distal	-7	no	83.022	82.959	EPSD	COSMIC	54.510	Down-regulation
CMGC_CDK_CDK4_CDK6_ST	Q92879	CELF1	Q00534	CDK6	S179	P180H	180	Missense	proximal	1	no	83.022	-10.103	EPSD	COSMIC	54.510	Loss
CMGC_CDK_CDK4_CDK6_ST	Q92879	CELF1	Q00534	CDK6	S179	A186T	186	Missense	distal	7	no	83.022	83.139	EPSD	COSMIC	54.510	Up-regulation
CMGC_CDK_CDK4_CDK6_ST	Q92879	CELF1	Q00534	CDK6	S179	V182G	182	Missense	distal	3	no	83.022	82.237	EPSD	COSMIC	54.510	Down-regulation
CMGC_CDK_CDK4_CDK6_ST	Q92879	CELF1	Q00534	CDK6	T295	S299R	299	Missense	distal	4	no	55.475	55.609	EPSD	COSMIC	54.510	Up-regulation
CMGC_CDK_CDK4_CDK6_ST	Q92879	CELF1	Q00534	CDK6	T295	S297L	297	Missense	proximal	2	no	55.475	55.558	EPSD	COSMIC	54.510	Up-regulation
CMGC_CDK_CDK4_CDK6_ST	Q92879	CELF1	Q00534	CDK6	T295	S302R	302	Missense	distal	7	no	55.475	55.058	EPSD	COSMIC	54.510	Down-regulation
CMGC_CDK_CDK4_CDK6_ST	Q92879	CELF1	Q00534	CDK6	T295	S296L	296	Missense	proximal	1	no	55.475	-11.893	EPSD	COSMIC	54.510	Loss
CMGC_CDK_CDK4_CDK6_ST	Q92879	CELF1	Q00534	CDK6	T295	P290R	290	Missense	distal	-5	no	55.475	55.707	EPSD	COSMIC	54.510	Up-regulation
CMGC_CDK_CDK4_CDK6_ST	Q92879	CELF1	Q00534	CDK6	T295	V293M	293	Missense	proximal	-2	no	55.475	55.503	EPSD	COSMIC	54.510	Up-regulation
CMGC_CDK_CDK4_CDK6_ST	Q92879	CELF1	Q00534	CDK6	T295	S300L	300	Missense	distal	5	no	55.475	55.086	EPSD	COSMIC	54.510	Down-regulation
CMGC_CDK_CDK4_CDK6_ST	Q92879	CELF1	Q00534	CDK6	T295	P290L	290	Missense	distal	-5	no	55.475	55.724	EPSD	COSMIC	54.510	Up-regulation
CMGC_CDK_CDK4_CDK6_ST	Q92879	CELF1	Q00534	CDK6	S296	S299R	299	Missense	distal	3	no	58.889	56.440	EPSD	COSMIC	54.510	Down-regulation
CMGC_CDK_CDK4_CDK6_ST	Q92879	CELF1	Q00534	CDK6	S296	S297L	297	Missense	proximal	1	no	58.889	-8.479	EPSD	COSMIC	54.510	Loss
CMGC_CDK_CDK4_CDK6_ST	Q92879	CELF1	Q00534	CDK6	S296	S302R	302	Missense	distal	6	no	58.889	58.836	EPSD	COSMIC	54.510	Down-regulation
CMGC_CDK_CDK4_CDK6_ST	Q92879	CELF1	Q00534	CDK6	S296	S296L	296	Missense	central	0	yes	58.889	0.000	EPSD	COSMIC	54.510	Loss
CMGC_CDK_CDK4_CDK6_ST	Q92879	CELF1	Q00534	CDK6	S296	P290R	290	Missense	distal	-6	no	58.889	59.102	EPSD	COSMIC	54.510	Up-regulation
CMGC_CDK_CDK4_CDK6_ST	Q92879	CELF1	Q00534	CDK6	S296	V293M	293	Missense	distal	-3	no	58.889	58.916	EPSD	COSMIC	54.510	Up-regulation
CMGC_CDK_CDK4_CDK6_ST	Q92879	CELF1	Q00534	CDK6	S296	S300L	300	Missense	distal	4	no	58.889	59.031	EPSD	COSMIC	54.510	Up-regulation
CMGC_CDK_CDK4_CDK6_ST	Q92879	CELF1	Q00534	CDK6	S296	P290L	290	Missense	distal	-6	no	58.889	59.119	EPSD	COSMIC	54.510	Up-regulation
CMGC_CDK_CDK4_CDK6_ST	Q92879	CELF1	Q00534	CDK6	S299	S305N	305	Missense	distal	6	no	57.914	57.875	EPSD	COSMIC	54.510	Down-regulation
CMGC_CDK_CDK4_CDK6_ST	Q92879	CELF1	Q00534	CDK6	S299	S299R	299	Missense	central	0	yes	57.914	0.000	EPSD	COSMIC	54.510	Loss
CMGC_CDK_CDK4_CDK6_ST	Q92879	CELF1	Q00534	CDK6	S299	S297L	297	Missense	proximal	-2	no	57.914	58.100	EPSD	COSMIC	54.510	Up-regulation
CMGC_CDK_CDK4_CDK6_ST	Q92879	CELF1	Q00534	CDK6	S299	S302R	302	Missense	distal	3	no	57.914	55.465	EPSD	COSMIC	54.510	Down-regulation
CMGC_CDK_CDK4_CDK6_ST	Q92879	CELF1	Q00534	CDK6	S299	S296L	296	Missense	distal	-3	no	57.914	58.066	EPSD	COSMIC	54.510	Up-regulation
CMGC_CDK_CDK4_CDK6_ST	Q92879	CELF1	Q00534	CDK6	S299	S306N	306	Missense	distal	7	no	57.914	57.538	EPSD	COSMIC	54.510	Down-regulation
CMGC_CDK_CDK4_CDK6_ST	Q92879	CELF1	Q00534	CDK6	S299	S304R	304	Missense	distal	5	no	57.914	57.583	EPSD	COSMIC	54.510	Down-regulation
CMGC_CDK_CDK4_CDK6_ST	Q92879	CELF1	Q00534	CDK6	S299	S305R	305	Missense	distal	6	no	57.914	57.861	EPSD	COSMIC	54.510	Down-regulation
CMGC_CDK_CDK4_CDK6_ST	Q92879	CELF1	Q00534	CDK6	S299	V293M	293	Missense	distal	-6	no	57.914	57.954	EPSD	COSMIC	54.510	Up-regulation
CMGC_CDK_CDK4_CDK6_ST	Q92879	CELF1	Q00534	CDK6	S299	S300L	300	Missense	proximal	1	no	57.914	-9.454	EPSD	COSMIC	54.510	Loss
CMGC_CDK_CDK4_CDK6_ST	Q92879	CELF1	Q00534	CDK6	S300	S305N	305	Missense	distal	5	no	86.266	85.969	EPSD	COSMIC	54.510	Down-regulation
CMGC_CDK_CDK4_CDK6_ST	Q92879	CELF1	Q00534	CDK6	S300	S299R	299	Missense	proximal	-1	no	86.266	86.188	EPSD	COSMIC	54.510	Down-regulation
CMGC_CDK_CDK4_CDK6_ST	Q92879	CELF1	Q00534	CDK6	S300	S297L	297	Missense	distal	-3	no	86.266	86.418	EPSD	COSMIC	54.510	Up-regulation
CMGC_CDK_CDK4_CDK6_ST	Q92879	CELF1	Q00534	CDK6	S300	S302R	302	Missense	proximal	2	no	86.266	86.343	EPSD	COSMIC	54.510	Up-regulation
CMGC_CDK_CDK4_CDK6_ST	Q92879	CELF1	Q00534	CDK6	S300	S296L	296	Missense	distal	-4	no	86.266	85.776	EPSD	COSMIC	54.510	Down-regulation
CMGC_CDK_CDK4_CDK6_ST	Q92879	CELF1	Q00534	CDK6	S300	S306N	306	Missense	distal	6	no	86.266	86.227	EPSD	COSMIC	54.510	Down-regulation
CMGC_CDK_CDK4_CDK6_ST	Q92879	CELF1	Q00534	CDK6	S300	S304R	304	Missense	distal	4	no	86.266	86.399	EPSD	COSMIC	54.510	Up-regulation
CMGC_CDK_CDK4_CDK6_ST	Q92879	CELF1	Q00534	CDK6	S300	S305R	305	Missense	distal	5	no	86.266	85.935	EPSD	COSMIC	54.510	Down-regulation
CMGC_CDK_CDK4_CDK6_ST	Q92879	CELF1	Q00534	CDK6	S300	V293M	293	Missense	distal	-7	no	86.266	86.146	EPSD	COSMIC	54.510	Down-regulation
CMGC_CDK_CDK4_CDK6_ST	Q92879	CELF1	Q00534	CDK6	S300	S300L	300	Missense	central	0	yes	86.266	0.000	EPSD	COSMIC	54.510	Loss
CMGC_CDK_CDK4_CDK6_ST	Q92879	CELF1	Q00534	CDK6	S302	S305N	305	Missense	distal	3	no	59.225	56.928	PhosphoSitePlus	COSMIC	54.510	Down-regulation
CMGC_CDK_CDK4_CDK6_ST	Q92879	CELF1	Q00534	CDK6	S302	S299R	299	Missense	distal	-3	no	59.225	59.362	PhosphoSitePlus	COSMIC	54.510	Up-regulation
CMGC_CDK_CDK4_CDK6_ST	Q92879	CELF1	Q00534	CDK6	S302	S297L	297	Missense	distal	-5	no	59.225	59.430	PhosphoSitePlus	COSMIC	54.510	Up-regulation
CMGC_CDK_CDK4_CDK6_ST	Q92879	CELF1	Q00534	CDK6	S302	S302R	302	Missense	central	0	yes	59.225	0.000	PhosphoSitePlus	COSMIC	54.510	Loss
CMGC_CDK_CDK4_CDK6_ST	Q92879	CELF1	Q00534	CDK6	S302	S296L	296	Missense	distal	-6	no	59.225	59.454	PhosphoSitePlus	COSMIC	54.510	Up-regulation
CMGC_CDK_CDK4_CDK6_ST	Q92879	CELF1	Q00534	CDK6	S302	S306N	306	Missense	distal	4	no	59.225	59.337	PhosphoSitePlus	COSMIC	54.510	Up-regulation
CMGC_CDK_CDK4_CDK6_ST	Q92879	CELF1	Q00534	CDK6	S302	S304R	304	Missense	proximal	2	no	59.225	59.302	PhosphoSitePlus	COSMIC	54.510	Up-regulation
CMGC_CDK_CDK4_CDK6_ST	Q92879	CELF1	Q00534	CDK6	S302	S305R	305	Missense	distal	3	no	59.225	56.776	PhosphoSitePlus	COSMIC	54.510	Down-regulation
CMGC_CDK_CDK4_CDK6_ST	Q92879	CELF1	Q00534	CDK6	S302	S300L	300	Missense	proximal	-2	no	59.225	59.411	PhosphoSitePlus	COSMIC	54.510	Up-regulation
CMGC_CDK_CDK4_CDK6_ST	Q92879	CELF1	Q00534	CDK6	S303	S305N	305	Missense	proximal	2	no	57.817	57.880	EPSD	COSMIC	54.510	Up-regulation
CMGC_CDK_CDK4_CDK6_ST	Q92879	CELF1	Q00534	CDK6	S303	S299R	299	Missense	distal	-4	no	57.817	57.344	EPSD	COSMIC	54.510	Down-regulation
CMGC_CDK_CDK4_CDK6_ST	Q92879	CELF1	Q00534	CDK6	S303	S297L	297	Missense	distal	-6	no	57.817	58.046	EPSD	COSMIC	54.510	Up-regulation
CMGC_CDK_CDK4_CDK6_ST	Q92879	CELF1	Q00534	CDK6	S303	S302R	302	Missense	proximal	-1	no	57.817	57.739	EPSD	COSMIC	54.510	Down-regulation
CMGC_CDK_CDK4_CDK6_ST	Q92879	CELF1	Q00534	CDK6	S303	S296L	296	Missense	distal	-7	no	57.817	57.069	EPSD	COSMIC	54.510	Down-regulation
CMGC_CDK_CDK4_CDK6_ST	Q92879	CELF1	Q00534	CDK6	S303	S306N	306	Missense	distal	3	no	57.817	55.521	EPSD	COSMIC	54.510	Down-regulation
CMGC_CDK_CDK4_CDK6_ST	Q92879	CELF1	Q00534	CDK6	S303	S304R	304	Missense	proximal	1	no	57.817	-2.754	EPSD	COSMIC	54.510	Loss
CMGC_CDK_CDK4_CDK6_ST	Q92879	CELF1	Q00534	CDK6	S303	S305R	305	Missense	proximal	2	no	57.817	57.894	EPSD	COSMIC	54.510	Up-regulation
CMGC_CDK_CDK4_CDK6_ST	Q92879	CELF1	Q00534	CDK6	S303	S300L	300	Missense	distal	-3	no	57.817	57.969	EPSD	COSMIC	54.510	Up-regulation
CMGC_CDK_CDK4_CDK6_ST	Q92879	CELF1	Q00534	CDK6	S304	S305N	305	Missense	proximal	1	no	55.227	-0.472	EPSD	COSMIC	54.510	Loss
CMGC_CDK_CDK4_CDK6_ST	Q92879	CELF1	Q00534	CDK6	S304	S299R	299	Missense	distal	-5	no	55.227	55.416	EPSD	COSMIC	54.510	Up-regulation
CMGC_CDK_CDK4_CDK6_ST	Q92879	CELF1	Q00534	CDK6	S304	S297L	297	Missense	distal	-7	no	55.227	54.479	EPSD	COSMIC	54.510	Loss
CMGC_CDK_CDK4_CDK6_ST	Q92879	CELF1	Q00534	CDK6	S304	S302R	302	Missense	proximal	-2	no	55.227	55.396	EPSD	COSMIC	54.510	Up-regulation
CMGC_CDK_CDK4_CDK6_ST	Q92879	CELF1	Q00534	CDK6	S304	S306N	306	Missense	proximal	2	no	55.227	55.291	EPSD	COSMIC	54.510	Up-regulation
CMGC_CDK_CDK4_CDK6_ST	Q92879	CELF1	Q00534	CDK6	S304	S304R	304	Missense	central	0	yes	55.227	0.000	EPSD	COSMIC	54.510	Loss
CMGC_CDK_CDK4_CDK6_ST	Q92879	CELF1	Q00534	CDK6	S304	S305R	305	Missense	proximal	1	no	55.227	-5.344	EPSD	COSMIC	54.510	Loss
CMGC_CDK_CDK4_CDK6_ST	Q92879	CELF1	Q00534	CDK6	S304	S300L	300	Missense	distal	-4	no	55.227	54.737	EPSD	COSMIC	54.510	Down-regulation
CMGC_CDK_CDK4_CDK6_ST	Q92879	CELF1	Q00534	CDK6	S305	S305N	305	Missense	central	0	yes	56.830	0.000	EPSD	COSMIC	54.510	Loss
CMGC_CDK_CDK4_CDK6_ST	Q92879	CELF1	Q00534	CDK6	S305	S299R	299	Missense	distal	-6	no	56.830	57.042	EPSD	COSMIC	54.510	Up-regulation
CMGC_CDK_CDK4_CDK6_ST	Q92879	CELF1	Q00534	CDK6	S305	S302R	302	Missense	distal	-3	no	56.830	56.967	EPSD	COSMIC	54.510	Up-regulation
CMGC_CDK_CDK4_CDK6_ST	Q92879	CELF1	Q00534	CDK6	S305	S306N	306	Missense	proximal	1	no	56.830	1.130	EPSD	COSMIC	54.510	Loss
CMGC_CDK_CDK4_CDK6_ST	Q92879	CELF1	Q00534	CDK6	S305	S304R	304	Missense	proximal	-1	no	56.830	56.752	EPSD	COSMIC	54.510	Down-regulation
CMGC_CDK_CDK4_CDK6_ST	Q92879	CELF1	Q00534	CDK6	S305	S305R	305	Missense	central	0	yes	56.830	0.000	EPSD	COSMIC	54.510	Loss
CMGC_CDK_CDK4_CDK6_ST	Q92879	CELF1	Q00534	CDK6	S305	I312T	312	Missense	distal	7	no	56.830	56.955	EPSD	COSMIC	54.510	Up-regulation
CMGC_CDK_CDK4_CDK6_ST	Q92879	CELF1	Q00534	CDK6	S305	S300L	300	Missense	distal	-5	no	56.830	57.035	EPSD	COSMIC	54.510	Up-regulation
CMGC_CDK_CDK4_CDK6_ST	Q16875	PFKFB3	Q00534	CDK6	S172	V168L	168	Missense	distal	-4	no	84.985	84.639	EPSD	COSMIC	54.510	Down-regulation
CMGC_CDK_CDK4_CDK6_ST	Q16875	PFKFB3	Q00534	CDK6	S172	K169N	169	Missense	distal	-3	no	84.985	85.022	EPSD	COSMIC	54.510	Up-regulation
CMGC_CDK_CDK4_CDK6_ST	Q16875	PFKFB3	Q00534	CDK6	T463	S467N	467	Missense	distal	4	no	84.581	84.693	EPSD;PhosphoSitePlus	COSMIC;GDSC;CCLE	54.510	Up-regulation
CMGC_CDK_CDK4_CDK6_ST	Q16875	PFKFB3	Q00534	CDK6	T463	S467L	467	Missense	distal	4	no	84.581	84.722	EPSD;PhosphoSitePlus	COSMIC	54.510	Up-regulation
CMGC_CDK_CDK4_CDK6_ST	Q16875	PFKFB3	Q00534	CDK6	S467	S467N	467	Missense	central	0	yes	86.405	0.000	PhosphoSitePlus;EPSD	COSMIC;GDSC;CCLE	54.510	Loss
CMGC_CDK_CDK4_CDK6_ST	Q16875	PFKFB3	Q00534	CDK6	S467	S467L	467	Missense	central	0	yes	86.405	0.000	PhosphoSitePlus;EPSD	COSMIC	54.510	Loss
CMGC_CDK_CDK4_CDK6_ST	Q16875	PFKFB3	Q00534	CDK6	S485	T486P	486	Missense	proximal	1	no	17.821	86.428	EPSD	COSMIC	54.510	Gain
CMGC_CDK_CDK4_CDK6_ST	P06748	NPM1	Q00534	CDK6	S10	R13S	13	Missense	distal	3	no	80.890	83.339	EPSD	COSMIC	54.510	Up-regulation
CMGC_CDK_CDK4_CDK6_ST	P06748	NPM1	Q00534	CDK6	S10	P14L	14	Missense	distal	4	no	80.890	81.116	EPSD	COSMIC	54.510	Up-regulation
CMGC_CDK_CDK4_CDK6_ST	P06748	NPM1	Q00534	CDK6	S70	G69D	69	Missense	proximal	-1	no	85.210	85.196	EPSD	COSMIC;GDSC;CCLE	54.510	Down-regulation
CMGC_CDK_CDK4_CDK6_ST	P06748	NPM1	Q00534	CDK6	T95	V98L	98	Missense	distal	3	no	84.970	84.252	EPSD	COSMIC	54.510	Down-regulation
CMGC_CDK_CDK4_CDK6_ST	P06748	NPM1	Q00534	CDK6	T199	P200S	200	Missense	proximal	1	no	86.828	57.189	PhosphoSitePlus	COSMIC	54.510	Down-regulation
CMGC_CDK_CDK4_CDK6_ST	P06748	NPM1	Q00534	CDK6	T199	S195F	195	Missense	distal	-4	no	86.828	86.309	PhosphoSitePlus	COSMIC	54.510	Down-regulation
CMGC_CDK_CDK4_CDK6_ST	P06748	NPM1	Q00534	CDK6	S217	G224R	224	Missense	distal	7	no	56.530	56.529	EPSD	COSMIC	54.510	Down-regulation
CMGC_CDK_CDK4_CDK6_ST	P06748	NPM1	Q00534	CDK6	T219	G224R	224	Missense	distal	5	no	88.146	88.143	EPSD	COSMIC	54.510	Down-regulation
CMGC_CDK_CDK4_CDK6_ST	P06748	NPM1	Q00534	CDK6	S227	F228S	228	Missense	proximal	1	no	-2.109	58.261	EPSD	COSMIC	54.510	Gain
CMGC_CDK_CDK4_CDK6_ST	P06748	NPM1	Q00534	CDK6	T234	F228S	228	Missense	distal	-6	no	86.772	86.568	EPSD	COSMIC	54.510	Down-regulation
CMGC_CDK_CDK4_CDK6_ST	P06748	NPM1	Q00534	CDK6	T234	S227F	227	Missense	distal	-7	no	86.772	86.005	EPSD	COSMIC	54.510	Down-regulation
CMGC_CDK_CDK4_CDK6_ST	P06748	NPM1	Q00534	CDK6	S242	D246N	246	Missense	distal	4	no	56.489	56.413	EPSD	COSMIC	54.510	Down-regulation
CMGC_CDK_CDK4_CDK6_ST	P06748	NPM1	Q00534	CDK6	S242	A249G	249	Missense	distal	7	no	56.489	56.405	EPSD	COSMIC	54.510	Down-regulation
CMGC_CDK_CDK8_CDK8_ST	Q15797	SMAD1	P49336	CDK8	S132	V130L	130	Missense	proximal	-2	no	32.431	32.979	EPSD	COSMIC	26.151	Up-regulation
CMGC_CDK_CDK8_CDK8_ST	Q15797	SMAD1	P49336	CDK8	S132	Y127C	127	Missense	distal	-5	no	32.431	32.334	EPSD	COSMIC	26.151	Down-regulation
CMGC_CDK_CDK8_CDK8_ST	Q15797	SMAD1	P49336	CDK8	S187	P188S	188	Missense	proximal	1	no	51.000	36.773	EPSD;PhosphoSitePlus	COSMIC	26.151	Down-regulation
CMGC_CDK_CDK8_CDK8_ST	Q15797	SMAD1	P49336	CDK8	S187	P183L	183	Missense	distal	-4	no	51.000	47.112	EPSD;PhosphoSitePlus	COSMIC;CCLE	26.151	Down-regulation
CMGC_CDK_CDK8_CDK8_ST	Q15797	SMAD1	P49336	CDK8	S195	P188S	188	Missense	distal	-7	no	50.921	50.993	PhosphoSitePlus;EPSD	COSMIC	26.151	Up-regulation
CMGC_CDK_CDK8_CDK8_ST	Q15797	SMAD1	P49336	CDK8	S206	H205Y	205	Missense	proximal	-1	no	50.529	50.758	EPSD;PhosphoSitePlus	COSMIC	26.151	Up-regulation
CMGC_CDK_CDK8_CDK8_ST	Q15797	SMAD1	P49336	CDK8	S206	H205N	205	Missense	proximal	-1	no	50.529	50.730	EPSD;PhosphoSitePlus	COSMIC	26.151	Up-regulation
CMGC_CDK_CDK8_CDK8_ST	Q15797	SMAD1	P49336	CDK8	S321	S315F	315	Missense	distal	-6	no	27.550	27.628	EPSD	COSMIC	26.151	Up-regulation
CMGC_CDK_CDK8_CDK8_ST	P46531	NOTCH1	P49336	CDK8	T535	C532W	532	Missense	distal	-3	no	31.052	31.132	EPSD	COSMIC	26.151	Up-regulation
CMGC_CDK_CDK8_CDK8_ST	P46531	NOTCH1	P49336	CDK8	T535	E531K	531	Missense	distal	-4	no	31.052	32.505	EPSD	COSMIC	26.151	Up-regulation
CMGC_CDK_CDK8_CDK8_ST	P46531	NOTCH1	P49336	CDK8	T535	P536L	536	Missense	proximal	1	no	31.052	5.198	EPSD	COSMIC	26.151	Loss
CMGC_CDK_CDK8_CDK8_ST	P46531	NOTCH1	P49336	CDK8	T1861	E1866K	1866	Missense	distal	5	no	28.750	30.278	EPSD	COSMIC	26.151	Up-regulation
CMGC_CDK_CDK8_CDK8_ST	P46531	NOTCH1	P49336	CDK8	T1861	M1855V	1855	Missense	distal	-6	no	28.750	28.724	EPSD	COSMIC	26.151	Down-regulation
CMGC_CDK_CDK8_CDK8_ST	P46531	NOTCH1	P49336	CDK8	T1861	V1867I	1867	Missense	distal	6	no	28.750	29.432	EPSD	COSMIC	26.151	Up-regulation
CMGC_CDK_CDK8_CDK8_ST	P46531	NOTCH1	P49336	CDK8	T1861	S1856C	1856	Missense	distal	-5	no	28.750	28.392	EPSD	COSMIC	26.151	Down-regulation
CMGC_CDK_CDK8_CDK8_ST	P46531	NOTCH1	P49336	CDK8	T1861	Q1864R	1864	Missense	distal	3	no	28.750	29.278	EPSD	COSMIC	26.151	Up-regulation
CMGC_CDK_CDK8_CDK8_ST	P46531	NOTCH1	P49336	CDK8	T1861	M1858L	1858	Missense	distal	-3	no	28.750	28.581	EPSD	COSMIC	26.151	Down-regulation
CMGC_CDK_CDK8_CDK8_ST	P46531	NOTCH1	P49336	CDK8	T1861	P1860L	1860	Missense	proximal	-1	no	28.750	28.545	EPSD	COSMIC	26.151	Down-regulation
CMGC_CDK_CDK8_CDK8_ST	P46531	NOTCH1	P49336	CDK8	S1941	A1943V	1943	Missense	proximal	2	no	27.022	26.698	EPSD	COSMIC	26.151	Down-regulation
CMGC_CDK_CDK8_CDK8_ST	P46531	NOTCH1	P49336	CDK8	S1941	A1944T	1944	Missense	distal	3	no	27.022	26.738	EPSD	COSMIC;CCLE	26.151	Down-regulation
CMGC_CDK_CDK8_CDK8_ST	P46531	NOTCH1	P49336	CDK8	S1941	R1937C	1937	Missense	distal	-4	no	27.022	25.071	EPSD	COSMIC	26.151	Loss
CMGC_CDK_CDK8_CDK8_ST	P46531	NOTCH1	P49336	CDK8	S1941	S1941F	1941	Missense	central	0	yes	27.022	0.000	EPSD	COSMIC	26.151	Loss
CMGC_CDK_CDK8_CDK8_ST	P46531	NOTCH1	P49336	CDK8	S1941	R1940C	1940	Missense	proximal	-1	no	27.022	26.847	EPSD	COSMIC	26.151	Down-regulation
CMGC_CDK_CDK8_CDK8_ST	P46531	NOTCH1	P49336	CDK8	S1941	A1935V	1935	Missense	distal	-6	no	27.022	27.005	EPSD	COSMIC	26.151	Down-regulation
CMGC_CDK_CDK8_CDK8_ST	P46531	NOTCH1	P49336	CDK8	S2136	P2133A	2133	Missense	distal	-3	no	39.195	39.340	EPSD	COSMIC	26.151	Up-regulation
CMGC_CDK_CDK8_CDK8_ST	P46531	NOTCH1	P49336	CDK8	S2136	L2139F	2139	Missense	distal	3	no	39.195	39.086	EPSD	COSMIC	26.151	Down-regulation
CMGC_CDK_CDK8_CDK8_ST	P46531	NOTCH1	P49336	CDK8	S2136	G2131N	2131	Missense	distal	-5	no	39.195	39.375	EPSD	COSMIC	26.151	Up-regulation
CMGC_CDK_CDK8_CDK8_ST	P46531	NOTCH1	P49336	CDK8	S2136	T2132M	2132	Missense	distal	-4	no	39.195	37.664	EPSD	COSMIC	26.151	Down-regulation
CMGC_CDK_CDK8_CDK8_ST	P46531	NOTCH1	P49336	CDK8	S2136	L2139P	2139	Missense	distal	3	no	39.195	42.739	EPSD	COSMIC	26.151	Up-regulation
CMGC_CDK_CDK8_CDK8_ST	P46531	NOTCH1	P49336	CDK8	S2136	L2129V	2129	Missense	distal	-7	no	39.195	39.151	EPSD	COSMIC	26.151	Down-regulation
CMGC_CDK_CDK8_CDK8_ST	P46531	NOTCH1	P49336	CDK8	S2136	C2140Y	2140	Missense	distal	4	no	39.195	39.150	EPSD	COSMIC	26.151	Down-regulation
CMGC_CDK_CDK8_CDK8_ST	P46531	NOTCH1	P49336	CDK8	S2141	L2139F	2139	Missense	proximal	-2	no	32.184	31.651	EPSD	COSMIC	26.151	Down-regulation
CMGC_CDK_CDK8_CDK8_ST	P46531	NOTCH1	P49336	CDK8	S2141	L2139P	2139	Missense	proximal	-2	no	32.184	44.842	EPSD	COSMIC	26.151	Up-regulation
CMGC_CDK_CDK8_CDK8_ST	P46531	NOTCH1	P49336	CDK8	S2141	S2148R	2148	Missense	distal	7	no	32.184	32.229	EPSD	COSMIC	26.151	Up-regulation
CMGC_CDK_CDK8_CDK8_ST	P46531	NOTCH1	P49336	CDK8	S2141	C2140Y	2140	Missense	proximal	-1	no	32.184	32.322	EPSD	COSMIC	26.151	Up-regulation
CMGC_CDK_CDK8_CDK8_ST	P46531	NOTCH1	P49336	CDK8	S2148	L2149P	2149	Missense	proximal	1	no	2.474	28.327	EPSD	COSMIC	26.151	Gain
CMGC_CDK_CDK8_CDK8_ST	P46531	NOTCH1	P49336	CDK8	S2162	V2158G	2158	Missense	distal	-4	no	27.147	26.104	EPSD	COSMIC	26.151	Loss
CMGC_CDK_CDK8_CDK8_ST	P46531	NOTCH1	P49336	CDK8	S2162	R2159H	2159	Missense	distal	-3	no	27.147	27.357	EPSD	COSMIC	26.151	Up-regulation
CMGC_CDK_CDK8_CDK8_ST	P46531	NOTCH1	P49336	CDK8	S2162	S2162I	2162	Missense	central	0	yes	27.147	0.000	EPSD	COSMIC	26.151	Loss
CMGC_CDK_CDK8_CDK8_ST	P46531	NOTCH1	P49336	CDK8	S2162	G2155C	2155	Missense	distal	-7	no	27.147	27.125	EPSD	COSMIC	26.151	Down-regulation
CMGC_CDK_CDK8_CDK8_ST	P46531	NOTCH1	P49336	CDK8	S2163	V2158G	2158	Missense	distal	-5	no	41.287	41.018	EPSD	COSMIC	26.151	Down-regulation
CMGC_CDK_CDK8_CDK8_ST	P46531	NOTCH1	P49336	CDK8	S2163	R2159H	2159	Missense	distal	-4	no	41.287	39.606	EPSD	COSMIC	26.151	Down-regulation
CMGC_CDK_CDK8_CDK8_ST	P46531	NOTCH1	P49336	CDK8	S2163	S2162I	2162	Missense	proximal	-1	no	41.287	41.372	EPSD	COSMIC	26.151	Up-regulation
CMGC_CDK_CDK8_CDK8_ST	P46531	NOTCH1	P49336	CDK8	S2215	S2221F	2221	Missense	distal	6	no	40.600	41.318	EPSD	COSMIC	26.151	Up-regulation
CMGC_CDK_CDK8_CDK8_ST	P46531	NOTCH1	P49336	CDK8	S2215	S2215L	2215	Missense	central	0	yes	40.600	0.000	EPSD	COSMIC;GDSC;CCLE	26.151	Loss
CMGC_CDK_CDK8_CDK8_ST	P46531	NOTCH1	P49336	CDK8	S2215	D2212N	2212	Missense	distal	-3	no	40.600	40.651	EPSD	COSMIC	26.151	Up-regulation
CMGC_CDK_CDK8_CDK8_ST	P46531	NOTCH1	P49336	CDK8	S2221	S2221F	2221	Missense	central	0	yes	37.631	0.000	EPSD	COSMIC	26.151	Loss
CMGC_CDK_CDK8_CDK8_ST	P46531	NOTCH1	P49336	CDK8	S2221	S2215L	2215	Missense	distal	-6	no	37.631	37.742	EPSD	COSMIC;GDSC;CCLE	26.151	Up-regulation
CMGC_CDK_CDK8_CDK8_ST	P46531	NOTCH1	P49336	CDK8	T2511	P2517L	2517	Missense	distal	6	no	25.276	26.606	EPSD;PhosphoSitePlus	COSMIC	26.151	Gain
CMGC_CDK_CDK8_CDK8_ST	P46531	NOTCH1	P49336	CDK8	T2511	H2507R	2507	Missense	distal	-4	no	25.276	26.956	EPSD;PhosphoSitePlus	COSMIC	26.151	Gain
CMGC_CDK_CDK8_CDK8_ST	P46531	NOTCH1	P49336	CDK8	T2511	F2509S	2509	Missense	proximal	-2	no	25.276	30.895	EPSD;PhosphoSitePlus	COSMIC	26.151	Gain
CMGC_CDK_CDK8_CDK8_ST	P46531	NOTCH1	P49336	CDK8	S2513	P2514R	2514	Missense	proximal	1	no	42.769	32.037	PhosphoSitePlus;EPSD	COSMIC	26.151	Down-regulation
CMGC_CDK_CDK8_CDK8_ST	P46531	NOTCH1	P49336	CDK8	S2513	P2517L	2517	Missense	distal	4	no	42.769	42.458	PhosphoSitePlus;EPSD	COSMIC	26.151	Down-regulation
CMGC_CDK_CDK8_CDK8_ST	P46531	NOTCH1	P49336	CDK8	S2513	H2507R	2507	Missense	distal	-6	no	42.769	42.672	PhosphoSitePlus;EPSD	COSMIC	26.151	Down-regulation
CMGC_CDK_CDK8_CDK8_ST	P46531	NOTCH1	P49336	CDK8	S2513	H2507Y	2507	Missense	distal	-6	no	42.769	42.743	PhosphoSitePlus;EPSD	COSMIC	26.151	Down-regulation
CMGC_CDK_CDK8_CDK8_ST	P46531	NOTCH1	P49336	CDK8	S2513	F2509S	2509	Missense	distal	-4	no	42.769	45.459	PhosphoSitePlus;EPSD	COSMIC	26.151	Up-regulation
CMGC_CDK_CDK8_CDK8_ST	P46531	NOTCH1	P49336	CDK8	S2513	L2510F	2510	Missense	distal	-3	no	42.769	42.902	PhosphoSitePlus;EPSD	COSMIC	26.151	Up-regulation
CMGC_CDK_CDK8_CDK8_ST	P46531	NOTCH1	P49336	CDK8	S2513	P2508A	2508	Missense	distal	-5	no	42.769	42.732	PhosphoSitePlus;EPSD	COSMIC	26.151	Down-regulation
CMGC_CDK_CDK8_CDK8_ST	P46531	NOTCH1	P49336	CDK8	S2513	P2514S	2514	Missense	proximal	1	no	42.769	28.542	PhosphoSitePlus;EPSD	COSMIC	26.151	Down-regulation
CMGC_CDK_CDK8_CDK8_ST	P46531	NOTCH1	P49336	CDK8	S2513	S2516A	2516	Missense	distal	3	no	42.769	42.526	PhosphoSitePlus;EPSD	COSMIC	26.151	Down-regulation
CMGC_CDK_CDK8_CDK8_ST	P46531	NOTCH1	P49336	CDK8	S2513	L2510R	2510	Missense	distal	-3	no	42.769	43.188	PhosphoSitePlus;EPSD	COSMIC	26.151	Up-regulation
CMGC_CDK_CDK8_CDK8_ST	P46531	NOTCH1	P49336	CDK8	S2513	S2513F	2513	Missense	central	0	yes	42.769	0.000	PhosphoSitePlus;EPSD	COSMIC	26.151	Loss
CMGC_CDK_CDK8_CDK8_ST	P46531	NOTCH1	P49336	CDK8	S2513	P2514L	2514	Missense	proximal	1	no	42.769	16.915	PhosphoSitePlus;EPSD	COSMIC	26.151	Loss
CMGC_CDK_CDK8_CDK8_ST	P46531	NOTCH1	P49336	CDK8	S2513	E2515K	2515	Missense	proximal	2	no	42.769	41.957	PhosphoSitePlus;EPSD	COSMIC	26.151	Down-regulation
CMGC_CDK_CDK8_CDK8_ST	P46531	NOTCH1	P49336	CDK8	S2513	L2510H	2510	Missense	distal	-3	no	42.769	43.397	PhosphoSitePlus;EPSD	COSMIC	26.151	Up-regulation
CMGC_CDK_CDK8_CDK8_ST	P46531	NOTCH1	P49336	CDK8	S2513	E2506K	2506	Missense	distal	-7	no	42.769	42.726	PhosphoSitePlus;EPSD	COSMIC	26.151	Down-regulation
CMGC_CDK_CDK8_CDK8_ST	P46531	NOTCH1	P49336	CDK8	S2516	P2514R	2514	Missense	proximal	-2	no	48.751	43.935	EPSD;PhosphoSitePlus	COSMIC	26.151	Down-regulation
CMGC_CDK_CDK8_CDK8_ST	P46531	NOTCH1	P49336	CDK8	S2516	P2517L	2517	Missense	proximal	1	no	48.751	22.898	EPSD;PhosphoSitePlus	COSMIC	26.151	Loss
CMGC_CDK_CDK8_CDK8_ST	P46531	NOTCH1	P49336	CDK8	S2516	F2509S	2509	Missense	distal	-7	no	48.751	48.688	EPSD;PhosphoSitePlus	COSMIC	26.151	Down-regulation
CMGC_CDK_CDK8_CDK8_ST	P46531	NOTCH1	P49336	CDK8	S2516	L2510F	2510	Missense	distal	-6	no	48.751	48.718	EPSD;PhosphoSitePlus	COSMIC	26.151	Down-regulation
CMGC_CDK_CDK8_CDK8_ST	P46531	NOTCH1	P49336	CDK8	S2516	P2514S	2514	Missense	proximal	-2	no	48.751	41.181	EPSD;PhosphoSitePlus	COSMIC	26.151	Down-regulation
CMGC_CDK_CDK8_CDK8_ST	P46531	NOTCH1	P49336	CDK8	S2516	S2516A	2516	Missense	central	0	yes	48.751	0.000	EPSD;PhosphoSitePlus	COSMIC	26.151	Loss
CMGC_CDK_CDK8_CDK8_ST	P46531	NOTCH1	P49336	CDK8	S2516	L2510R	2510	Missense	distal	-6	no	48.751	48.647	EPSD;PhosphoSitePlus	COSMIC	26.151	Down-regulation
CMGC_CDK_CDK8_CDK8_ST	P46531	NOTCH1	P49336	CDK8	S2516	S2513F	2513	Missense	distal	-3	no	48.751	48.765	EPSD;PhosphoSitePlus	COSMIC	26.151	Up-regulation
CMGC_CDK_CDK8_CDK8_ST	P46531	NOTCH1	P49336	CDK8	S2516	P2514L	2514	Missense	proximal	-2	no	48.751	36.094	EPSD;PhosphoSitePlus	COSMIC	26.151	Down-regulation
CMGC_CDK_CDK8_CDK8_ST	P46531	NOTCH1	P49336	CDK8	S2516	E2515K	2515	Missense	proximal	-1	no	48.751	48.917	EPSD;PhosphoSitePlus	COSMIC	26.151	Up-regulation
CMGC_CDK_CDK8_CDK8_ST	P46531	NOTCH1	P49336	CDK8	S2516	L2510H	2510	Missense	distal	-6	no	48.751	48.744	EPSD;PhosphoSitePlus	COSMIC	26.151	Down-regulation
CMGC_CDK_CDK8_CDK8_ST	P46531	NOTCH1	P49336	CDK8	S2524	P2525L	2525	Missense	proximal	1	no	35.106	9.252	EPSD	COSMIC	26.151	Loss
CMGC_CDK_CDK8_CDK8_ST	P46531	NOTCH1	P49336	CDK8	S2524	P2517L	2517	Missense	distal	-7	no	35.106	35.258	EPSD	COSMIC	26.151	Up-regulation
CMGC_CDK_CDK8_CDK8_ST	P46531	NOTCH1	P49336	CDK8	S2524	S2530C	2530	Missense	distal	6	no	35.106	35.751	EPSD	COSMIC	26.151	Up-regulation
CMGC_CDK_CDK8_CDK8_ST	P46531	NOTCH1	P49336	CDK8	S2524	P2525S	2525	Missense	proximal	1	no	35.106	20.879	EPSD	COSMIC	26.151	Loss
CMGC_CDK_CDK8_CDK8_ST	P46531	NOTCH1	P49336	CDK8	S2524	V2529I	2529	Missense	distal	5	no	35.106	34.519	EPSD	COSMIC	26.151	Down-regulation
CMGC_CDK_CDK8_CDK8_ST	P46531	NOTCH1	P49336	CDK8	S2524	H2526Q	2526	Missense	proximal	2	no	35.106	36.452	EPSD	COSMIC	26.151	Up-regulation
CMGC_CDK_CDK8_CDK8_ST	P46531	NOTCH1	P49336	CDK8	S2524	H2526N	2526	Missense	proximal	2	no	35.106	35.251	EPSD	COSMIC	26.151	Up-regulation
CMGC_CDK_CDK8_CDK8_ST	P46531	NOTCH1	P49336	CDK8	S2524	H2526R	2526	Missense	proximal	2	no	35.106	35.167	EPSD	COSMIC	26.151	Up-regulation
CMGC_CDK_CDK8_CDK8_ST	P84022	SMAD3	P49336	CDK8	T179	N175D	175	Missense	distal	-4	no	49.631	51.412	EPSD;PhosphoSitePlus	COSMIC	26.151	Up-regulation
CMGC_CDK_CDK8_CDK8_ST	P84022	SMAD3	P49336	CDK8	T179	P182S	182	Missense	distal	3	no	49.631	48.331	EPSD;PhosphoSitePlus	COSMIC	26.151	Down-regulation
CMGC_CDK_CDK8_CDK8_ST	P84022	SMAD3	P49336	CDK8	T179	P177L	177	Missense	proximal	-2	no	49.631	36.974	EPSD;PhosphoSitePlus	COSMIC	26.151	Down-regulation
CMGC_CDK_CDK8_CDK8_ST	P84022	SMAD3	P49336	CDK8	T179	P172H	172	Missense	distal	-7	no	49.631	49.673	EPSD;PhosphoSitePlus	COSMIC	26.151	Up-regulation
CMGC_CDK_CDK8_CDK8_ST	P84022	SMAD3	P49336	CDK8	S204	S204N	204	Missense	central	0	yes	32.440	0.000	EPSD	COSMIC	26.151	Loss
CMGC_CDK_CDK8_CDK8_ST	P84022	SMAD3	P49336	CDK8	S204	P211S	211	Missense	distal	7	no	32.440	32.240	EPSD	COSMIC	26.151	Down-regulation
CMGC_CDK_CDK8_CDK8_ST	P84022	SMAD3	P49336	CDK8	S204	A202T	202	Missense	proximal	-2	no	32.440	34.355	EPSD	COSMIC	26.151	Up-regulation
CMGC_CDK_CDK8_CDK8_ST	P84022	SMAD3	P49336	CDK8	S204	S204F	204	Missense	central	0	yes	32.440	0.000	EPSD	COSMIC	26.151	Loss
CMGC_CDK_CDK8_CDK8_ST	P84022	SMAD3	P49336	CDK8	S204	P211L	211	Missense	distal	7	no	32.440	31.420	EPSD	COSMIC	26.151	Down-regulation
CMGC_CDK_CDK8_CDK8_ST	P84022	SMAD3	P49336	CDK8	S204	P209S	209	Missense	distal	5	no	32.440	30.737	EPSD	COSMIC	26.151	Down-regulation
CMGC_CDK_CDK8_CDK8_ST	P84022	SMAD3	P49336	CDK8	S204	N197K	197	Missense	distal	-7	no	32.440	32.421	EPSD	COSMIC	26.151	Down-regulation
CMGC_CDK_CDK8_CDK8_ST	P84022	SMAD3	P49336	CDK8	S208	S204N	204	Missense	distal	-4	no	50.292	49.203	PhosphoSitePlus;EPSD	COSMIC	26.151	Down-regulation
CMGC_CDK_CDK8_CDK8_ST	P84022	SMAD3	P49336	CDK8	S208	P211S	211	Missense	distal	3	no	50.292	48.991	PhosphoSitePlus;EPSD	COSMIC	26.151	Down-regulation
CMGC_CDK_CDK8_CDK8_ST	P84022	SMAD3	P49336	CDK8	S208	S204F	204	Missense	distal	-4	no	50.292	47.602	PhosphoSitePlus;EPSD	COSMIC	26.151	Down-regulation
CMGC_CDK_CDK8_CDK8_ST	P84022	SMAD3	P49336	CDK8	S208	P211L	211	Missense	distal	3	no	50.292	46.748	PhosphoSitePlus;EPSD	COSMIC	26.151	Down-regulation
CMGC_CDK_CDK8_CDK8_ST	P84022	SMAD3	P49336	CDK8	S208	P209S	209	Missense	proximal	1	no	50.292	36.065	PhosphoSitePlus;EPSD	COSMIC	26.151	Down-regulation
CMGC_CDK_CDK8_CDK8_ST	P84022	SMAD3	P49336	CDK8	S213	P211S	211	Missense	proximal	-2	no	51.172	43.601	EPSD;PhosphoSitePlus	COSMIC	26.151	Down-regulation
CMGC_CDK_CDK8_CDK8_ST	P84022	SMAD3	P49336	CDK8	S213	P211L	211	Missense	proximal	-2	no	51.172	38.515	EPSD;PhosphoSitePlus	COSMIC	26.151	Down-regulation
CMGC_CDK_CDK8_CDK8_ST	P84022	SMAD3	P49336	CDK8	S213	P209S	209	Missense	distal	-4	no	51.172	50.928	EPSD;PhosphoSitePlus	COSMIC	26.151	Down-regulation
CMGC_CDK_CDK8_CDK8_ST	P84022	SMAD3	P49336	CDK8	S416	S423G	423	Missense	distal	7	no	27.595	27.242	EPSD	COSMIC	26.151	Down-regulation
CMGC_CDK_CDK8_CDK8_ST	P84022	SMAD3	P49336	CDK8	S416	S423I	423	Missense	distal	7	no	27.595	27.145	EPSD	COSMIC	26.151	Down-regulation
CMGC_CDK_CDK8_CDK8_ST	P84022	SMAD3	P49336	CDK8	S416	V410I	410	Missense	distal	-6	no	27.595	27.694	EPSD	COSMIC	26.151	Up-regulation
CMGC_CDK_CDK8_CDK8_ST	P84022	SMAD3	P49336	CDK8	S416	S422Y	422	Missense	distal	6	no	27.595	28.107	EPSD	COSMIC	26.151	Up-regulation
CMGC_CDK_CDK8_CDK8_ST	P84022	SMAD3	P49336	CDK8	S416	C421Y	421	Missense	distal	5	no	27.595	29.054	EPSD	COSMIC	26.151	Up-regulation
CMGC_CDK_CDK8_CDK8_ST	P84022	SMAD3	P49336	CDK8	S416	R420C	420	Missense	distal	4	no	27.595	27.479	EPSD	COSMIC	26.151	Down-regulation
CMGC_CDK_CDK8_CDK8_ST	Q01094	E2F1	P49336	CDK8	S121	H114Y	114	Missense	distal	-7	no	29.253	29.293	EPSD	COSMIC	26.151	Up-regulation
CMGC_CDK_CDK8_CDK8_ST	Q01094	E2F1	P49336	CDK8	S121	R127L	127	Missense	distal	6	no	29.253	30.298	EPSD	COSMIC	26.151	Up-regulation
CMGC_CDK_CDK8_CDK8_ST	Q01094	E2F1	P49336	CDK8	S121	G116V	116	Missense	distal	-5	no	29.253	29.522	EPSD	COSMIC	26.151	Up-regulation
CMGC_CDK_CDK8_CDK8_ST	Q01094	E2F1	P49336	CDK8	S307	P312L	312	Missense	distal	5	no	31.092	27.448	EPSD	COSMIC	26.151	Down-regulation
CMGC_CDK_CDK8_CDK8_ST	Q01094	E2F1	P49336	CDK8	S332	S336L	336	Missense	distal	4	no	32.784	32.504	EPSD	COSMIC	26.151	Down-regulation
CMGC_CDK_CDK8_CDK8_ST	Q01094	E2F1	P49336	CDK8	S332	I330T	330	Missense	proximal	-2	no	32.784	42.525	EPSD	COSMIC	26.151	Up-regulation
CMGC_CDK_CDK8_CDK8_ST	Q01094	E2F1	P49336	CDK8	S332	P335Q	335	Missense	distal	3	no	32.784	31.170	EPSD	COSMIC;GDSC;CCLE	26.151	Down-regulation
CMGC_CDK_CDK8_CDK8_ST	Q01094	E2F1	P49336	CDK8	S332	P335S	335	Missense	distal	3	no	32.784	31.483	EPSD	COSMIC	26.151	Down-regulation
CMGC_CDK_CDK8_CDK8_ST	Q01094	E2F1	P49336	CDK8	S332	P334L	334	Missense	proximal	2	no	32.784	34.855	EPSD	COSMIC	26.151	Up-regulation
CMGC_CDK_CDK8_CDK8_ST	Q01094	E2F1	P49336	CDK8	S336	S341F	341	Missense	distal	5	no	32.191	30.927	EPSD	COSMIC	26.151	Down-regulation
CMGC_CDK_CDK8_CDK8_ST	Q01094	E2F1	P49336	CDK8	S336	S336L	336	Missense	central	0	yes	32.191	0.000	EPSD	COSMIC	26.151	Loss
CMGC_CDK_CDK8_CDK8_ST	Q01094	E2F1	P49336	CDK8	S336	I330T	330	Missense	distal	-6	no	32.191	32.108	EPSD	COSMIC	26.151	Down-regulation
CMGC_CDK_CDK8_CDK8_ST	Q01094	E2F1	P49336	CDK8	S336	P335Q	335	Missense	proximal	-1	no	32.191	31.899	EPSD	COSMIC;GDSC;CCLE	26.151	Down-regulation
CMGC_CDK_CDK8_CDK8_ST	Q01094	E2F1	P49336	CDK8	S336	P335S	335	Missense	proximal	-1	no	32.191	31.994	EPSD	COSMIC	26.151	Down-regulation
CMGC_CDK_CDK8_CDK8_ST	Q01094	E2F1	P49336	CDK8	S336	P334L	334	Missense	proximal	-2	no	32.191	19.533	EPSD	COSMIC	26.151	Loss
CMGC_CDK_CDK8_CDK8_ST	Q01094	E2F1	P49336	CDK8	S337	S341F	341	Missense	distal	4	no	33.597	33.423	EPSD	COSMIC	26.151	Down-regulation
CMGC_CDK_CDK8_CDK8_ST	Q01094	E2F1	P49336	CDK8	S337	S336L	336	Missense	proximal	-1	no	33.597	33.588	EPSD	COSMIC	26.151	Down-regulation
CMGC_CDK_CDK8_CDK8_ST	Q01094	E2F1	P49336	CDK8	S337	I330T	330	Missense	distal	-7	no	33.597	33.453	EPSD	COSMIC	26.151	Down-regulation
CMGC_CDK_CDK8_CDK8_ST	Q01094	E2F1	P49336	CDK8	S337	P335Q	335	Missense	proximal	-2	no	33.597	18.148	EPSD	COSMIC;GDSC;CCLE	26.151	Loss
CMGC_CDK_CDK8_CDK8_ST	Q01094	E2F1	P49336	CDK8	S337	P335S	335	Missense	proximal	-2	no	33.597	26.026	EPSD	COSMIC	26.151	Loss
CMGC_CDK_CDK8_CDK8_ST	Q01094	E2F1	P49336	CDK8	S337	P334L	334	Missense	distal	-3	no	33.597	33.369	EPSD	COSMIC	26.151	Down-regulation
CMGC_CDK_CDK8_CDK8_ST	Q01094	E2F1	P49336	CDK8	S340	S341F	341	Missense	proximal	1	no	29.318	15.460	EPSD	COSMIC	26.151	Loss
CMGC_CDK_CDK8_CDK8_ST	Q01094	E2F1	P49336	CDK8	S340	P346S	346	Missense	distal	6	no	29.318	29.767	EPSD	COSMIC;GDSC	26.151	Up-regulation
CMGC_CDK_CDK8_CDK8_ST	Q01094	E2F1	P49336	CDK8	S340	S336L	336	Missense	distal	-4	no	29.318	25.676	EPSD	COSMIC	26.151	Loss
CMGC_CDK_CDK8_CDK8_ST	Q01094	E2F1	P49336	CDK8	S340	P335Q	335	Missense	distal	-5	no	29.318	29.576	EPSD	COSMIC;GDSC;CCLE	26.151	Up-regulation
CMGC_CDK_CDK8_CDK8_ST	Q01094	E2F1	P49336	CDK8	S340	P335S	335	Missense	distal	-5	no	29.318	29.513	EPSD	COSMIC	26.151	Up-regulation
CMGC_CDK_CDK8_CDK8_ST	Q01094	E2F1	P49336	CDK8	S340	P334L	334	Missense	distal	-6	no	29.318	29.436	EPSD	COSMIC	26.151	Up-regulation
CMGC_CDK_CDK8_CDK8_ST	Q01094	E2F1	P49336	CDK8	S375	S382L	382	Missense	distal	7	no	49.538	48.719	PhosphoSitePlus	COSMIC	26.151	Down-regulation
CMGC_CDK_CDK8_CDK8_ST	Q01094	E2F1	P49336	CDK8	S403	P404S	404	Missense	proximal	1	no	31.917	17.690	EPSD	COSMIC	26.151	Loss
CMGC_CDK_CDK8_CDK8_ST	P51946	CCNH	P49336	CDK8	S5	N4I	4	Missense	proximal	-1	no	34.219	34.058	PhosphoSitePlus;EPSD	COSMIC	26.151	Down-regulation
CMGC_CDK_CDK8_CDK8_ST	P51946	CCNH	P49336	CDK8	S121	N119Y	119	Missense	proximal	-2	no	26.372	24.268	EPSD	COSMIC	26.151	Loss
CMGC_CDK_CDK8_CDK8_ST	P51946	CCNH	P49336	CDK8	S304	E310D	310	Missense	distal	6	no	39.633	39.478	EPSD;PhosphoSitePlus	COSMIC	26.151	Down-regulation
CMGC_CDK_CDK8_CDK8_ST	P51946	CCNH	P49336	CDK8	S304	H309R	309	Missense	distal	5	no	39.633	40.887	EPSD;PhosphoSitePlus	COSMIC	26.151	Up-regulation
CMGC_CDK_CDK8_CDK8_ST	P51946	CCNH	P49336	CDK8	S304	K308N	308	Missense	distal	4	no	39.633	39.492	EPSD;PhosphoSitePlus	COSMIC	26.151	Down-regulation
CMGC_CDK_CDK8_CDK8_ST	P51946	CCNH	P49336	CDK8	S304	D299V	299	Missense	distal	-5	no	39.633	39.222	EPSD;PhosphoSitePlus	COSMIC	26.151	Down-regulation
TK_Fak_PTK2_Y	Q9H5V8	CDCP1	Q05397	PTK2	Y806	Y806H	806	Missense	central	0	yes	0.000	0.000	EPSD	COSMIC	0.000	Loss
TK_Fak_PTK2_Y	P26010	ITGB7	Q05397	PTK2	Y753	Y753H	753	Missense	central	0	yes	0.000	0.000	EPSD;PhosphoSitePlus	COSMIC	0.000	Loss
TK_Fak_PTK2_Y	P26010	ITGB7	Q05397	PTK2	Y758	Y758N	758	Missense	central	0	yes	0.000	0.000	PhosphoSitePlus;EPSD	COSMIC	0.000	Loss
TK_Fak_PTK2_Y	Q05397	PTK2	Q05397	PTK2	Y148	Y148C	148	Missense	central	0	yes	0.000	0.000	EPSD	COSMIC	0.000	Loss
TK_Fak_PTK2_Y	Q05397	PTK2	Q05397	PTK2	Y155	Y155C	155	Missense	central	0	yes	0.000	0.000	EPSD	COSMIC;CCLE	0.000	Loss
TK_Fak_PTK2_Y	Q05397	PTK2	Q05397	PTK2	Y441	Y441F	441	Missense	central	0	yes	0.000	0.000	EPSD	COSMIC	0.000	Loss
TK_Fak_PTK2_Y	Q05397	PTK2	Q05397	PTK2	Y925	Y925C	925	Missense	central	0	yes	0.000	0.000	EPSD	COSMIC	0.000	Loss
TK_Fak_PTK2_Y	P07949	RET	Q05397	PTK2	Y791	Y791F	791	Missense	central	0	yes	0.000	0.000	EPSD	COSMIC;GDSC	0.000	Loss
TK_Fak_PTK2_Y	P07949	RET	Q05397	PTK2	Y791	Y791N	791	Missense	central	0	yes	0.000	0.000	EPSD	COSMIC;GDSC;CCLE	0.000	Loss
TK_Fak_PTK2_Y	P07949	RET	Q05397	PTK2	Y826	Y826F	826	Missense	central	0	yes	0.000	0.000	EPSD	COSMIC	0.000	Loss
TK_Fak_PTK2_Y	P07949	RET	Q05397	PTK2	Y905	Y905D	905	Missense	central	0	yes	0.000	0.000	PhosphoSitePlus	COSMIC	0.000	Loss
TK_Fak_PTK2_Y	Q9Y2X7	GIT1	Q05397	PTK2	Y284	Y284H	284	Missense	central	0	yes	0.000	0.000	EPSD	COSMIC	0.000	Loss
TK_Fak_PTK2_Y	Q9Y2X7	GIT1	Q05397	PTK2	Y598	Y598H	598	Missense	central	0	yes	0.000	0.000	EPSD	COSMIC	0.000	Loss
TK_Fak_PTK2_Y	Q14451	GRB7	Q05397	PTK2	Y259	Y259C	259	Missense	central	0	yes	0.000	0.000	EPSD	COSMIC	0.000	Loss
TK_Fak_PTK2_Y	O75962	TRIO	Q05397	PTK2	Y2075	Y2075C	2075	Missense	central	0	yes	0.000	0.000	EPSD	COSMIC;GDSC;CCLE	0.000	Loss
TK_Fak_PTK2_Y	P56945	BCAR1	Q05397	PTK2	Y128	Y128C	128	Missense	central	0	yes	0.000	0.000	EPSD	COSMIC	0.000	Loss
TK_Fak_PTK2_Y	P56945	BCAR1	Q05397	PTK2	Y249	Y249N	249	Missense	central	0	yes	0.000	0.000	EPSD	COSMIC	0.000	Loss
TK_Fak_PTK2_Y	P56945	BCAR1	Q05397	PTK2	Y267	Y267N	267	Missense	central	0	yes	0.000	0.000	EPSD	COSMIC	0.000	Loss
TK_Fak_PTK2_Y	P56945	BCAR1	Q05397	PTK2	Y287	Y287C	287	Missense	central	0	yes	0.000	0.000	EPSD	COSMIC	0.000	Loss
TK_Fak_PTK2_Y	P56945	BCAR1	Q05397	PTK2	Y306	Y306H	306	Missense	central	0	yes	0.000	0.000	EPSD	COSMIC	0.000	Loss
TK_Fak_PTK2_Y	P56945	BCAR1	Q05397	PTK2	Y664	Y664C	664	Missense	central	0	yes	0.000	0.000	EPSD	COSMIC	0.000	Loss
TK_Fak_PTK2_Y	P56945	BCAR1	Q05397	PTK2	Y666	Y666C	666	Missense	central	0	yes	0.000	0.000	EPSD	COSMIC	0.000	Loss
AGC_RSK_RSKp90_RPS6KA1_ST	O95071	UBR5	Q15418	RPS6KA1	S115	R122M	122	Missense	distal	7	no	1.788	1.682	EPSD	COSMIC	1.787	Loss
AGC_RSK_RSKp90_RPS6KA1_ST	O95071	UBR5	Q15418	RPS6KA1	S115	S108R	108	Missense	distal	-7	no	1.788	1.810	EPSD	COSMIC	1.787	Up-regulation
AGC_RSK_RSKp90_RPS6KA1_ST	O95071	UBR5	Q15418	RPS6KA1	S115	W112S	112	Missense	distal	-3	no	1.788	1.822	EPSD	COSMIC;GDSC;CCLE	1.787	Up-regulation
AGC_RSK_RSKp90_RPS6KA1_ST	O95071	UBR5	Q15418	RPS6KA1	S305	R311H	311	Missense	distal	6	no	2.894	2.914	EPSD	COSMIC	1.787	Up-regulation
AGC_RSK_RSKp90_RPS6KA1_ST	O95071	UBR5	Q15418	RPS6KA1	S305	R311C	311	Missense	distal	6	no	2.894	2.716	EPSD	COSMIC	1.787	Down-regulation
AGC_RSK_RSKp90_RPS6KA1_ST	O95071	UBR5	Q15418	RPS6KA1	S305	E306K	306	Missense	proximal	1	no	2.894	2.937	EPSD	COSMIC	1.787	Up-regulation
AGC_RSK_RSKp90_RPS6KA1_ST	O95071	UBR5	Q15418	RPS6KA1	S305	E312A	312	Missense	distal	7	no	2.894	2.819	EPSD	COSMIC	1.787	Down-regulation
AGC_RSK_RSKp90_RPS6KA1_ST	O95071	UBR5	Q15418	RPS6KA1	S636	M629V	629	Missense	distal	-7	no	1.931	1.887	EPSD	COSMIC	1.787	Down-regulation
AGC_RSK_RSKp90_RPS6KA1_ST	O95071	UBR5	Q15418	RPS6KA1	S636	E643Q	643	Missense	distal	7	no	1.931	1.969	EPSD	COSMIC	1.787	Up-regulation
AGC_RSK_RSKp90_RPS6KA1_ST	O95071	UBR5	Q15418	RPS6KA1	S636	R635W	635	Missense	proximal	-1	no	1.931	2.100	EPSD	COSMIC	1.787	Up-regulation
AGC_RSK_RSKp90_RPS6KA1_ST	O95071	UBR5	Q15418	RPS6KA1	S636	P638S	638	Missense	proximal	2	no	1.931	1.753	EPSD	COSMIC	1.787	Loss
AGC_RSK_RSKp90_RPS6KA1_ST	O95071	UBR5	Q15418	RPS6KA1	S636	P630Q	630	Missense	distal	-6	no	1.931	1.736	EPSD	COSMIC	1.787	Loss
AGC_RSK_RSKp90_RPS6KA1_ST	O95071	UBR5	Q15418	RPS6KA1	S695	N690D	690	Missense	distal	-5	no	2.186	2.162	EPSD	COSMIC;GDSC	1.787	Down-regulation
AGC_RSK_RSKp90_RPS6KA1_ST	O95071	UBR5	Q15418	RPS6KA1	S928	N935K	935	Missense	distal	7	no	2.222	2.091	EPSD	COSMIC;CCLE	1.787	Down-regulation
AGC_RSK_RSKp90_RPS6KA1_ST	O95071	UBR5	Q15418	RPS6KA1	S928	S934N	934	Missense	distal	6	no	2.222	2.284	EPSD	COSMIC	1.787	Up-regulation
AGC_RSK_RSKp90_RPS6KA1_ST	O95071	UBR5	Q15418	RPS6KA1	S928	S928N	928	Missense	central	0	yes	2.222	0.000	EPSD	COSMIC	1.787	Loss
AGC_RSK_RSKp90_RPS6KA1_ST	O95071	UBR5	Q15418	RPS6KA1	S1025	P1019T	1019	Missense	distal	-6	no	1.497	1.854	EPSD	COSMIC	1.787	Gain
AGC_RSK_RSKp90_RPS6KA1_ST	O95071	UBR5	Q15418	RPS6KA1	T1115	M1118I	1118	Missense	distal	3	no	1.869	1.914	EPSD	COSMIC	1.787	Up-regulation
AGC_RSK_RSKp90_RPS6KA1_ST	O95071	UBR5	Q15418	RPS6KA1	T1115	G1113R	1113	Missense	proximal	-2	no	1.869	1.736	EPSD	COSMIC	1.787	Loss
AGC_RSK_RSKp90_RPS6KA1_ST	O95071	UBR5	Q15418	RPS6KA1	S1119	G1123V	1123	Missense	distal	4	no	2.058	1.982	EPSD	COSMIC	1.787	Down-regulation
AGC_RSK_RSKp90_RPS6KA1_ST	O95071	UBR5	Q15418	RPS6KA1	S1119	M1118I	1118	Missense	proximal	-1	no	2.058	1.850	EPSD	COSMIC	1.787	Down-regulation
AGC_RSK_RSKp90_RPS6KA1_ST	O95071	UBR5	Q15418	RPS6KA1	S1119	R1124Q	1124	Missense	distal	5	no	2.058	1.857	EPSD	COSMIC	1.787	Down-regulation
AGC_RSK_RSKp90_RPS6KA1_ST	O95071	UBR5	Q15418	RPS6KA1	S1119	G1113R	1113	Missense	distal	-6	no	2.058	1.150	EPSD	COSMIC	1.787	Loss
AGC_RSK_RSKp90_RPS6KA1_ST	O95071	UBR5	Q15418	RPS6KA1	T1306	P1309L	1309	Missense	distal	3	no	2.726	2.790	EPSD	COSMIC	1.787	Up-regulation
AGC_RSK_RSKp90_RPS6KA1_ST	O95071	UBR5	Q15418	RPS6KA1	T1306	R1302H	1302	Missense	distal	-4	no	2.726	2.583	EPSD	COSMIC	1.787	Down-regulation
AGC_RSK_RSKp90_RPS6KA1_ST	O95071	UBR5	Q15418	RPS6KA1	T1306	R1304Q	1304	Missense	proximal	-2	no	2.726	2.801	EPSD	COSMIC	1.787	Up-regulation
AGC_RSK_RSKp90_RPS6KA1_ST	O95071	UBR5	Q15418	RPS6KA1	S1375	V1369L	1369	Missense	distal	-6	no	1.463	2.150	EPSD	COSMIC	1.787	Gain
AGC_RSK_RSKp90_RPS6KA1_ST	O95071	UBR5	Q15418	RPS6KA1	S1481	A1479G	1479	Missense	proximal	-2	no	2.181	2.272	EPSD	COSMIC	1.787	Up-regulation
AGC_RSK_RSKp90_RPS6KA1_ST	O95071	UBR5	Q15418	RPS6KA1	S1549	R1547L	1547	Missense	proximal	-2	no	3.013	3.083	EPSD	COSMIC	1.787	Up-regulation
AGC_RSK_RSKp90_RPS6KA1_ST	O95071	UBR5	Q15418	RPS6KA1	S1549	Q1550K	1550	Missense	proximal	1	no	3.013	3.044	EPSD	COSMIC	1.787	Up-regulation
AGC_RSK_RSKp90_RPS6KA1_ST	O95071	UBR5	Q15418	RPS6KA1	S1549	R1555Q	1555	Missense	distal	6	no	3.013	2.961	EPSD	COSMIC	1.787	Down-regulation
AGC_RSK_RSKp90_RPS6KA1_ST	O95071	UBR5	Q15418	RPS6KA1	T1699	G1706V	1706	Missense	distal	7	no	1.913	1.931	EPSD	COSMIC	1.787	Up-regulation
AGC_RSK_RSKp90_RPS6KA1_ST	O95071	UBR5	Q15418	RPS6KA1	S1733	A1726S	1726	Missense	distal	-7	no	1.950	1.955	EPSD	COSMIC	1.787	Up-regulation
AGC_RSK_RSKp90_RPS6KA1_ST	O95071	UBR5	Q15418	RPS6KA1	S1733	A1726T	1726	Missense	distal	-7	no	1.950	1.945	EPSD	COSMIC	1.787	Down-regulation
AGC_RSK_RSKp90_RPS6KA1_ST	O95071	UBR5	Q15418	RPS6KA1	S1733	T1729S	1729	Missense	distal	-4	no	1.950	1.843	EPSD	COSMIC	1.787	Down-regulation
AGC_RSK_RSKp90_RPS6KA1_ST	O95071	UBR5	Q15418	RPS6KA1	T1734	T1729S	1729	Missense	distal	-5	no	1.862	1.663	EPSD	COSMIC	1.787	Loss
AGC_RSK_RSKp90_RPS6KA1_ST	O95071	UBR5	Q15418	RPS6KA1	S1761	A1763P	1763	Missense	proximal	2	no	1.550	1.922	EPSD	COSMIC	1.787	Gain
AGC_RSK_RSKp90_RPS6KA1_ST	O95071	UBR5	Q15418	RPS6KA1	S1761	A1763V	1763	Missense	proximal	2	no	1.550	1.858	EPSD	COSMIC	1.787	Gain
AGC_RSK_RSKp90_RPS6KA1_ST	O95071	UBR5	Q15418	RPS6KA1	T1902	R1907H	1907	Missense	distal	5	no	2.686	2.339	EPSD	COSMIC;GDSC	1.787	Down-regulation
AGC_RSK_RSKp90_RPS6KA1_ST	O95071	UBR5	Q15418	RPS6KA1	T1902	R1900C	1900	Missense	proximal	-2	no	2.686	2.774	EPSD	COSMIC	1.787	Up-regulation
AGC_RSK_RSKp90_RPS6KA1_ST	O95071	UBR5	Q15418	RPS6KA1	T1902	A1901T	1901	Missense	proximal	-1	no	2.686	2.871	EPSD	COSMIC	1.787	Up-regulation
AGC_RSK_RSKp90_RPS6KA1_ST	O95071	UBR5	Q15418	RPS6KA1	T1902	T1902N	1902	Missense	central	0	yes	2.686	0.000	EPSD	COSMIC	1.787	Loss
AGC_RSK_RSKp90_RPS6KA1_ST	O95071	UBR5	Q15418	RPS6KA1	T1902	R1898K	1898	Missense	distal	-4	no	2.686	2.659	EPSD	COSMIC	1.787	Down-regulation
AGC_RSK_RSKp90_RPS6KA1_ST	O95071	UBR5	Q15418	RPS6KA1	T1902	R1907P	1907	Missense	distal	5	no	2.686	2.481	EPSD	COSMIC	1.787	Down-regulation
AGC_RSK_RSKp90_RPS6KA1_ST	O95071	UBR5	Q15418	RPS6KA1	T1902	R1900H	1900	Missense	proximal	-2	no	2.686	2.774	EPSD	COSMIC	1.787	Up-regulation
AGC_RSK_RSKp90_RPS6KA1_ST	O95071	UBR5	Q15418	RPS6KA1	S2241	V2244A	2244	Missense	distal	3	no	2.102	2.098	EPSD	COSMIC	1.787	Down-regulation
AGC_RSK_RSKp90_RPS6KA1_ST	O95071	UBR5	Q15418	RPS6KA1	S2241	R2248Q	2248	Missense	distal	7	no	2.102	2.061	EPSD	COSMIC	1.787	Down-regulation
AGC_RSK_RSKp90_RPS6KA1_ST	O95071	UBR5	Q15418	RPS6KA1	S2241	R2246Q	2246	Missense	distal	5	no	2.102	1.901	EPSD	COSMIC	1.787	Down-regulation
AGC_RSK_RSKp90_RPS6KA1_ST	O95071	UBR5	Q15418	RPS6KA1	S2356	R2362K	2362	Missense	distal	6	no	1.849	1.751	EPSD	COSMIC	1.787	Loss
AGC_RSK_RSKp90_RPS6KA1_ST	O95071	UBR5	Q15418	RPS6KA1	S2356	D2359N	2359	Missense	distal	3	no	1.849	1.785	EPSD	COSMIC	1.787	Loss
AGC_RSK_RSKp90_RPS6KA1_ST	O95071	UBR5	Q15418	RPS6KA1	S2356	R2358G	2358	Missense	proximal	2	no	1.849	1.854	EPSD	COSMIC	1.787	Up-regulation
AGC_RSK_RSKp90_RPS6KA1_ST	O95071	UBR5	Q15418	RPS6KA1	S2356	R2353Q	2353	Missense	distal	-3	no	1.849	1.439	EPSD	COSMIC	1.787	Loss
AGC_RSK_RSKp90_RPS6KA1_ST	O95071	UBR5	Q15418	RPS6KA1	S2424	M2419V	2419	Missense	distal	-5	no	1.932	2.088	EPSD	COSMIC	1.787	Up-regulation
AGC_RSK_RSKp90_RPS6KA1_ST	O95071	UBR5	Q15418	RPS6KA1	S2424	E2422K	2422	Missense	proximal	-2	no	1.932	1.966	EPSD	COSMIC	1.787	Up-regulation
AGC_RSK_RSKp90_RPS6KA1_ST	O95071	UBR5	Q15418	RPS6KA1	S2424	Q2427E	2427	Missense	distal	3	no	1.932	1.946	EPSD	COSMIC	1.787	Up-regulation
AGC_RSK_RSKp90_RPS6KA1_ST	O95071	UBR5	Q15418	RPS6KA1	S2434	A2433E	2433	Missense	proximal	-1	no	1.732	1.861	EPSD	COSMIC	1.787	Gain
AGC_RSK_RSKp90_RPS6KA1_ST	O95071	UBR5	Q15418	RPS6KA1	S2437	A2433E	2433	Missense	distal	-4	no	2.475	2.491	EPSD	COSMIC	1.787	Up-regulation
AGC_RSK_RSKp90_RPS6KA1_ST	O95071	UBR5	Q15418	RPS6KA1	S2470	E2471K	2471	Missense	proximal	1	no	2.581	2.625	EPSD	COSMIC	1.787	Up-regulation
AGC_RSK_RSKp90_RPS6KA1_ST	O95071	UBR5	Q15418	RPS6KA1	S2470	V2467L	2467	Missense	distal	-3	no	2.581	3.236	EPSD	COSMIC	1.787	Up-regulation
AGC_RSK_RSKp90_RPS6KA1_ST	Q13164	MAPK7	Q15418	RPS6KA1	S337	A339T	339	Missense	proximal	2	no	1.768	2.059	EPSD	COSMIC	1.787	Gain
AGC_RSK_RSKp90_RPS6KA1_ST	Q13164	MAPK7	Q15418	RPS6KA1	S337	R335C	335	Missense	proximal	-2	no	1.768	1.856	EPSD	COSMIC	1.787	Gain
AGC_RSK_RSKp90_RPS6KA1_ST	Q13164	MAPK7	Q15418	RPS6KA1	S433	M431I	431	Missense	proximal	-2	no	2.033	2.035	EPSD	COSMIC	1.787	Up-regulation
AGC_RSK_RSKp90_RPS6KA1_ST	Q13164	MAPK7	Q15418	RPS6KA1	S433	P438L	438	Missense	distal	5	no	2.033	2.021	EPSD	COSMIC	1.787	Down-regulation
AGC_RSK_RSKp90_RPS6KA1_ST	Q13164	MAPK7	Q15418	RPS6KA1	S486	D493Y	493	Missense	distal	7	no	2.773	2.815	EPSD	COSMIC	1.787	Up-regulation
AGC_RSK_RSKp90_RPS6KA1_ST	Q13164	MAPK7	Q15418	RPS6KA1	S486	L484F	484	Missense	proximal	-2	no	2.773	2.780	EPSD	COSMIC	1.787	Up-regulation
AGC_RSK_RSKp90_RPS6KA1_ST	Q13164	MAPK7	Q15418	RPS6KA1	S486	A481D	481	Missense	distal	-5	no	2.773	2.987	EPSD	COSMIC	1.787	Up-regulation
AGC_RSK_RSKp90_RPS6KA1_ST	Q13164	MAPK7	Q15418	RPS6KA1	S496	D493Y	493	Missense	distal	-3	no	1.849	1.807	PhosphoSitePlus	COSMIC	1.787	Down-regulation
AGC_RSK_RSKp90_RPS6KA1_ST	Q13164	MAPK7	Q15418	RPS6KA1	S496	A497T	497	Missense	proximal	1	no	1.849	1.774	PhosphoSitePlus	COSMIC	1.787	Loss
AGC_RSK_RSKp90_RPS6KA1_ST	Q13164	MAPK7	Q15418	RPS6KA1	S720	E723K	723	Missense	distal	3	no	2.079	2.144	EPSD	COSMIC;GDSC;CCLE	1.787	Up-regulation
AGC_RSK_RSKp90_RPS6KA1_ST	Q13164	MAPK7	Q15418	RPS6KA1	S720	S718F	718	Missense	proximal	-2	no	2.079	2.089	EPSD	COSMIC;GDSC;CCLE	1.787	Up-regulation
AGC_RSK_RSKp90_RPS6KA1_ST	O60343	TBC1D4	Q15418	RPS6KA1	S44	G43W	43	Missense	proximal	-1	no	2.694	2.551	EPSD	COSMIC	1.787	Down-regulation
AGC_RSK_RSKp90_RPS6KA1_ST	O60343	TBC1D4	Q15418	RPS6KA1	S292	T290I	290	Missense	proximal	-2	no	1.869	1.832	EPSD	COSMIC	1.787	Down-regulation
AGC_RSK_RSKp90_RPS6KA1_ST	O60343	TBC1D4	Q15418	RPS6KA1	S292	R293W	293	Missense	proximal	1	no	1.869	1.891	EPSD	COSMIC	1.787	Up-regulation
AGC_RSK_RSKp90_RPS6KA1_ST	O60343	TBC1D4	Q15418	RPS6KA1	S576	R577M	577	Missense	proximal	1	no	1.987	1.990	EPSD	COSMIC	1.787	Up-regulation
AGC_RSK_RSKp90_RPS6KA1_ST	O60343	TBC1D4	Q15418	RPS6KA1	S631	P627L	627	Missense	distal	-4	no	2.054	2.123	EPSD	COSMIC	1.787	Up-regulation
AGC_RSK_RSKp90_RPS6KA1_ST	O60343	TBC1D4	Q15418	RPS6KA1	S702	T701N	701	Missense	proximal	-1	no	1.790	1.791	EPSD	COSMIC	1.787	Up-regulation
AGC_RSK_RSKp90_RPS6KA1_ST	O60343	TBC1D4	Q15418	RPS6KA1	S702	L699F	699	Missense	distal	-3	no	1.790	1.309	EPSD	COSMIC	1.787	Loss
AGC_RSK_RSKp90_RPS6KA1_ST	O60343	TBC1D4	Q15418	RPS6KA1	S702	P697L	697	Missense	distal	-5	no	1.790	1.795	EPSD	COSMIC	1.787	Up-regulation
AGC_RSK_RSKp90_RPS6KA1_ST	O60343	TBC1D4	Q15418	RPS6KA1	S716	A710T	710	Missense	distal	-6	no	1.575	2.001	EPSD	COSMIC	1.787	Gain
AGC_RSK_RSKp90_RPS6KA1_ST	O60343	TBC1D4	Q15418	RPS6KA1	S787	S787A	787	Missense	central	0	yes	2.464	0.000	EPSD	COSMIC	1.787	Loss
AGC_RSK_RSKp90_RPS6KA1_ST	O60343	TBC1D4	Q15418	RPS6KA1	S787	A781D	781	Missense	distal	-6	no	2.464	2.307	EPSD	COSMIC	1.787	Down-regulation
AGC_RSK_RSKp90_RPS6KA1_ST	O60343	TBC1D4	Q15418	RPS6KA1	S787	M791I	791	Missense	distal	4	no	2.464	2.478	EPSD	COSMIC	1.787	Up-regulation
AGC_RSK_RSKp90_RPS6KA1_ST	O60343	TBC1D4	Q15418	RPS6KA1	S787	P783A	783	Missense	distal	-4	no	2.464	2.380	EPSD	COSMIC	1.787	Down-regulation
AGC_RSK_RSKp90_RPS6KA1_ST	O60343	TBC1D4	Q15418	RPS6KA1	T811	E814Q	814	Missense	distal	3	no	2.128	2.114	EPSD	COSMIC	1.787	Down-regulation
AGC_RSK_RSKp90_RPS6KA1_ST	O60343	TBC1D4	Q15418	RPS6KA1	T811	S809F	809	Missense	proximal	-2	no	2.128	2.139	EPSD	COSMIC	1.787	Up-regulation
AGC_RSK_RSKp90_RPS6KA1_ST	O60343	TBC1D4	Q15418	RPS6KA1	S1122	I1116M	1116	Missense	distal	-6	no	1.892	1.649	EPSD	COSMIC	1.787	Loss
AGC_RSK_RSKp90_RPS6KA1_ST	O60343	TBC1D4	Q15418	RPS6KA1	S1122	L1123R	1123	Missense	proximal	1	no	1.892	1.868	EPSD	COSMIC;GDSC;CCLE	1.787	Down-regulation
AGC_RSK_RSKp90_RPS6KA1_ST	O60343	TBC1D4	Q15418	RPS6KA1	S1122	L1121R	1121	Missense	proximal	-1	no	1.892	1.839	EPSD	COSMIC	1.787	Down-regulation
AGC_RSK_RSKp90_RPS6KA1_ST	O60343	TBC1D4	Q15418	RPS6KA1	S1126	L1123R	1123	Missense	distal	-3	no	2.136	2.052	EPSD	COSMIC;GDSC;CCLE	1.787	Down-regulation
AGC_RSK_RSKp90_RPS6KA1_ST	O60343	TBC1D4	Q15418	RPS6KA1	S1126	M1132I	1132	Missense	distal	6	no	2.136	2.125	EPSD	COSMIC	1.787	Down-regulation
AGC_RSK_RSKp90_RPS6KA1_ST	O60343	TBC1D4	Q15418	RPS6KA1	S1126	E1133G	1133	Missense	distal	7	no	2.136	2.274	EPSD	COSMIC	1.787	Up-regulation
AGC_RSK_RSKp90_RPS6KA1_ST	O60343	TBC1D4	Q15418	RPS6KA1	S1126	L1121R	1121	Missense	distal	-5	no	2.136	1.973	EPSD	COSMIC	1.787	Down-regulation
AGC_RSK_RSKp90_RPS6KA1_ST	O60343	TBC1D4	Q15418	RPS6KA1	S1207	A1205T	1205	Missense	proximal	-2	no	1.857	1.923	EPSD	COSMIC	1.787	Up-regulation
AGC_RSK_RSKp90_RPS6KA1_ST	Q92934	BAD	Q15418	RPS6KA1	S34	A27T	27	Missense	distal	-7	no	1.868	1.863	EPSD	COSMIC;GDSC;CCLE	1.787	Down-regulation
AGC_RSK_RSKp90_RPS6KA1_ST	Q92934	BAD	Q15418	RPS6KA1	S75	A78E	78	Missense	distal	3	no	3.978	3.970	PhosphoSitePlus	COSMIC	1.787	Down-regulation
AGC_RSK_RSKp90_RPS6KA1_ST	Q92934	BAD	Q15418	RPS6KA1	S124	S124F	124	Missense	central	0	yes	2.480	0.000	EPSD	COSMIC	1.787	Loss
AGC_RSK_RSKp90_RPS6KA1_ST	Q92934	BAD	Q15418	RPS6KA1	S124	K127N	127	Missense	distal	3	no	2.480	2.359	EPSD	COSMIC	1.787	Down-regulation
AGC_RSK_RSKp90_RPS6KA1_ST	P19634	SLC9A1	Q15418	RPS6KA1	T42	A43T	43	Missense	proximal	1	no	2.718	2.643	EPSD	COSMIC;GDSC;CCLE	1.787	Down-regulation
AGC_RSK_RSKp90_RPS6KA1_ST	Q8IX03	WWC1	Q15418	RPS6KA1	S623	A628P	628	Missense	distal	5	no	2.119	2.075	EPSD	COSMIC	1.787	Down-regulation
AGC_RSK_RSKp90_RPS6KA1_ST	Q8IX03	WWC1	Q15418	RPS6KA1	S974	S981F	981	Missense	distal	7	no	1.905	1.963	EPSD	COSMIC	1.787	Up-regulation
AGC_RSK_RSKp90_RPS6KA1_ST	Q8IX03	WWC1	Q15418	RPS6KA1	S974	M970I	970	Missense	distal	-4	no	1.905	1.810	EPSD	COSMIC	1.787	Down-regulation
AGC_RSK_RSKp90_RPS6KA1_ST	Q8IX03	WWC1	Q15418	RPS6KA1	S974	S981L	981	Missense	distal	7	no	1.905	1.913	EPSD	COSMIC	1.787	Up-regulation
AGC_RSK_RSKp90_RPS6KA1_ST	Q9UN36	NDRG2	Q15418	RPS6KA1	T366	S360L	360	Missense	distal	-6	no	1.436	1.935	EPSD	COSMIC	1.787	Gain
AGC_RSK_RSKp90_RPS6KA1_ST	Q9UN36	NDRG2	Q15418	RPS6KA1	T366	P363L	363	Missense	distal	-3	no	1.436	2.021	EPSD	COSMIC	1.787	Gain
AGC_RSK_RSKp90_RPS6KA1_ST	Q8N122	RPTOR	Q15418	RPS6KA1	T126	L123F	123	Missense	distal	-3	no	2.082	1.600	EPSD	COSMIC	1.787	Loss
AGC_RSK_RSKp90_RPS6KA1_ST	Q8N122	RPTOR	Q15418	RPS6KA1	T126	T126N	126	Missense	central	0	yes	2.082	0.000	EPSD	COSMIC	1.787	Loss
AGC_RSK_RSKp90_RPS6KA1_ST	Q8N122	RPTOR	Q15418	RPS6KA1	S696	E689K	689	Missense	distal	-7	no	2.534	2.509	EPSD	COSMIC	1.787	Down-regulation
AGC_RSK_RSKp90_RPS6KA1_ST	Q8N122	RPTOR	Q15418	RPS6KA1	S696	S696Y	696	Missense	central	0	yes	2.534	0.000	EPSD	COSMIC	1.787	Loss
AGC_RSK_RSKp90_RPS6KA1_ST	Q8N122	RPTOR	Q15418	RPS6KA1	S696	A693T	693	Missense	distal	-3	no	2.534	2.088	EPSD	COSMIC;GDSC;CCLE	1.787	Down-regulation
AGC_RSK_RSKp90_RPS6KA1_ST	Q8N122	RPTOR	Q15418	RPS6KA1	S696	G702E	702	Missense	distal	6	no	2.534	2.654	EPSD	COSMIC	1.787	Up-regulation
AGC_RSK_RSKp90_RPS6KA1_ST	Q8N122	RPTOR	Q15418	RPS6KA1	S696	S696A	696	Missense	central	0	yes	2.534	0.000	EPSD	COSMIC	1.787	Loss
AGC_RSK_RSKp90_RPS6KA1_ST	Q8N122	RPTOR	Q15418	RPS6KA1	S798	S792F	792	Missense	distal	-6	no	1.751	1.879	EPSD	COSMIC	1.787	Gain
AGC_RSK_RSKp90_RPS6KA1_ST	Q8N122	RPTOR	Q15418	RPS6KA1	S854	P861L	861	Missense	distal	7	no	2.647	2.552	EPSD	COSMIC	1.787	Down-regulation
AGC_RSK_RSKp90_RPS6KA1_ST	Q8N122	RPTOR	Q15418	RPS6KA1	S854	V850I	850	Missense	distal	-4	no	2.647	2.742	EPSD	COSMIC	1.787	Up-regulation
AGC_RSK_RSKp90_RPS6KA1_ST	Q8N122	RPTOR	Q15418	RPS6KA1	S854	S854A	854	Missense	central	0	yes	2.647	0.000	EPSD	COSMIC	1.787	Loss
AGC_RSK_RSKp90_RPS6KA1_ST	Q8N122	RPTOR	Q15418	RPS6KA1	T908	R905L	905	Missense	distal	-3	no	1.723	1.807	EPSD	COSMIC	1.787	Gain
AGC_RSK_RSKp90_RPS6KA1_ST	Q8N122	RPTOR	Q15418	RPS6KA1	T908	P911L	911	Missense	distal	3	no	1.723	1.788	EPSD	COSMIC	1.787	Gain
AGC_RSK_RSKp90_RPS6KA1_ST	Q8N122	RPTOR	Q15418	RPS6KA1	S920	Q922R	922	Missense	proximal	2	no	1.748	1.983	EPSD	COSMIC	1.787	Gain
AGC_RSK_RSKp90_RPS6KA1_ST	Q8N122	RPTOR	Q15418	RPS6KA1	S1116	A1111T	1111	Missense	distal	-5	no	1.822	2.000	EPSD	COSMIC	1.787	Up-regulation
AGC_RSK_RSKp90_RPS6KA1_ST	Q8N122	RPTOR	Q15418	RPS6KA1	S1116	S1116L	1116	Missense	central	0	yes	1.822	0.000	EPSD	COSMIC;GDSC;CCLE	1.787	Loss
AGC_RSK_RSKp90_RPS6KA1_ST	Q8N122	RPTOR	Q15418	RPS6KA1	S1116	T1121M	1121	Missense	distal	5	no	1.822	1.845	EPSD	COSMIC	1.787	Up-regulation
AGC_RSK_RSKp90_RPS6KA1_ST	Q8N122	RPTOR	Q15418	RPS6KA1	S1116	V1109E	1109	Missense	distal	-7	no	1.822	1.874	EPSD	COSMIC	1.787	Up-regulation
AGC_RSK_RSKp90_RPS6KA1_ST	Q8N122	RPTOR	Q15418	RPS6KA1	S1116	Q1113H	1113	Missense	distal	-3	no	1.822	1.813	EPSD	COSMIC;CCLE	1.787	Down-regulation
AGC_RSK_RSKp90_RPS6KA1_ST	Q8N122	RPTOR	Q15418	RPS6KA1	S1116	D1117Y	1117	Missense	proximal	1	no	1.822	1.878	EPSD	COSMIC	1.787	Up-regulation
AGC_RSK_RSKp90_RPS6KA1_ST	Q8N122	RPTOR	Q15418	RPS6KA1	S1116	L1119Q	1119	Missense	distal	3	no	1.822	1.712	EPSD	COSMIC	1.787	Loss
AGC_RSK_RSKp90_RPS6KA1_ST	Q8N122	RPTOR	Q15418	RPS6KA1	S1116	T1122M	1122	Missense	distal	6	no	1.822	1.926	EPSD	COSMIC	1.787	Up-regulation
AGC_RSK_RSKp90_RPS6KA1_ST	Q8N122	RPTOR	Q15418	RPS6KA1	S1189	G1184C	1184	Missense	distal	-5	no	2.822	2.905	EPSD	COSMIC	1.787	Up-regulation
AGC_RSK_RSKp90_RPS6KA1_ST	Q8N122	RPTOR	Q15418	RPS6KA1	S1189	R1191C	1191	Missense	proximal	2	no	2.822	2.931	EPSD	COSMIC	1.787	Up-regulation
AGC_RSK_RSKp90_RPS6KA1_ST	Q8N122	RPTOR	Q15418	RPS6KA1	S1189	R1196S	1196	Missense	distal	7	no	2.822	2.715	EPSD	COSMIC	1.787	Down-regulation
AGC_RSK_RSKp90_RPS6KA1_ST	Q8N122	RPTOR	Q15418	RPS6KA1	S1189	R1191S	1191	Missense	proximal	2	no	2.822	2.670	EPSD	COSMIC	1.787	Down-regulation
AGC_RSK_RSKp90_RPS6KA1_ST	P50552	VASP	Q15418	RPS6KA1	S239	G246V	246	Missense	distal	7	no	2.179	2.197	EPSD	COSMIC	1.787	Up-regulation
AGC_RSK_RSKp90_RPS6KA1_ST	P16220	CREB1	Q15418	RPS6KA1	T104	S103N	103	Missense	proximal	-1	no	2.270	2.209	EPSD	COSMIC	1.787	Down-regulation
AGC_RSK_RSKp90_RPS6KA1_ST	P16220	CREB1	Q15418	RPS6KA1	T104	E109K	109	Missense	distal	5	no	2.270	2.157	EPSD	COSMIC	1.787	Down-regulation
AGC_RSK_RSKp90_RPS6KA1_ST	P16220	CREB1	Q15418	RPS6KA1	T104	I102M	102	Missense	proximal	-2	no	2.270	2.268	EPSD	COSMIC	1.787	Down-regulation
AGC_RSK_RSKp90_RPS6KA1_ST	P16220	CREB1	Q15418	RPS6KA1	S133	L128R	128	Missense	distal	-5	no	5.441	5.278	PhosphoSitePlus	COSMIC	1.787	Down-regulation
AGC_RSK_RSKp90_RPS6KA1_ST	P16220	CREB1	Q15418	RPS6KA1	S271	A269T	269	Missense	proximal	-2	no	1.838	1.904	EPSD	COSMIC	1.787	Up-regulation
AGC_RSK_RSKp90_RPS6KA1_ST	P16220	CREB1	Q15418	RPS6KA1	S271	P264T	264	Missense	distal	-7	no	1.838	1.836	EPSD	COSMIC;GDSC;CCLE	1.787	Down-regulation
AGC_RSK_RSKp90_RPS6KA1_ST	Q2M1Z3	ARHGAP31	Q15418	RPS6KA1	S382	G384D	384	Missense	proximal	2	no	2.612	2.470	EPSD	COSMIC	1.787	Down-regulation
AGC_RSK_RSKp90_RPS6KA1_ST	Q2M1Z3	ARHGAP31	Q15418	RPS6KA1	S382	M380I	380	Missense	proximal	-2	no	2.612	2.614	EPSD	COSMIC	1.787	Up-regulation
AGC_RSK_RSKp90_RPS6KA1_ST	Q2M1Z3	ARHGAP31	Q15418	RPS6KA1	S506	A500T	500	Missense	distal	-6	no	1.476	1.902	EPSD	COSMIC	1.787	Gain
AGC_RSK_RSKp90_RPS6KA1_ST	Q2M1Z3	ARHGAP31	Q15418	RPS6KA1	S629	A634V	634	Missense	distal	5	no	2.075	2.160	EPSD	COSMIC	1.787	Up-regulation
AGC_RSK_RSKp90_RPS6KA1_ST	Q2M1Z3	ARHGAP31	Q15418	RPS6KA1	S680	P673S	673	Missense	distal	-7	no	1.981	1.989	EPSD	COSMIC	1.787	Up-regulation
AGC_RSK_RSKp90_RPS6KA1_ST	Q2M1Z3	ARHGAP31	Q15418	RPS6KA1	S680	P684L	684	Missense	distal	4	no	1.981	2.005	EPSD	COSMIC	1.787	Up-regulation
AGC_RSK_RSKp90_RPS6KA1_ST	Q2M1Z3	ARHGAP31	Q15418	RPS6KA1	S957	D956G	956	Missense	proximal	-1	no	1.879	1.998	EPSD	COSMIC	1.787	Up-regulation
AGC_RSK_RSKp90_RPS6KA1_ST	Q2M1Z3	ARHGAP31	Q15418	RPS6KA1	S957	R950H	950	Missense	distal	-7	no	1.879	1.845	EPSD	COSMIC;CCLE	1.787	Down-regulation
AGC_RSK_RSKp90_RPS6KA1_ST	Q2M1Z3	ARHGAP31	Q15418	RPS6KA1	S957	S954Y	954	Missense	distal	-3	no	1.879	1.786	EPSD	COSMIC	1.787	Loss
AGC_RSK_RSKp90_RPS6KA1_ST	Q2M1Z3	ARHGAP31	Q15418	RPS6KA1	S972	P970L	970	Missense	proximal	-2	no	2.080	2.074	EPSD	COSMIC	1.787	Down-regulation
AGC_RSK_RSKp90_RPS6KA1_ST	Q2M1Z3	ARHGAP31	Q15418	RPS6KA1	S972	V969I	969	Missense	distal	-3	no	2.080	2.525	EPSD	COSMIC	1.787	Up-regulation
AGC_RSK_RSKp90_RPS6KA1_ST	Q2M1Z3	ARHGAP31	Q15418	RPS6KA1	S1036	P1037L	1037	Missense	proximal	1	no	1.987	2.035	EPSD	COSMIC	1.787	Up-regulation
AGC_RSK_RSKp90_RPS6KA1_ST	Q2M1Z3	ARHGAP31	Q15418	RPS6KA1	S1054	Q1056E	1056	Missense	proximal	2	no	3.090	3.314	EPSD	COSMIC	1.787	Up-regulation
AGC_RSK_RSKp90_RPS6KA1_ST	Q2M1Z3	ARHGAP31	Q15418	RPS6KA1	S1178	R1176H	1176	Missense	proximal	-2	no	2.286	2.374	EPSD;PhosphoSitePlus	COSMIC	1.787	Up-regulation
AGC_RSK_RSKp90_RPS6KA1_ST	Q2M1Z3	ARHGAP31	Q15418	RPS6KA1	S1178	R1175P	1175	Missense	distal	-3	no	2.286	1.784	EPSD;PhosphoSitePlus	COSMIC	1.787	Loss
AGC_RSK_RSKp90_RPS6KA1_ST	Q2M1Z3	ARHGAP31	Q15418	RPS6KA1	S1384	S1378N	1378	Missense	distal	-6	no	1.771	1.875	EPSD	COSMIC	1.787	Gain
AGC_RSK_RSKp90_RPS6KA1_ST	Q2M1Z3	ARHGAP31	Q15418	RPS6KA1	S1384	T1380P	1380	Missense	distal	-4	no	1.771	1.854	EPSD	COSMIC	1.787	Gain
AGC_RSK_RSKp90_RPS6KA1_ST	P49841	GSK3B	Q15418	RPS6KA1	T59	G65E	65	Missense	distal	6	no	1.676	1.795	EPSD	COSMIC;GDSC;CCLE	1.787	Gain
AGC_RSK_RSKp90_RPS6KA1_ST	P49841	GSK3B	Q15418	RPS6KA1	T324	R319C	319	Missense	distal	-5	no	2.230	2.517	EPSD	COSMIC	1.787	Up-regulation
AGC_RSK_RSKp90_RPS6KA1_ST	P49841	GSK3B	Q15418	RPS6KA1	T324	R319Q	319	Missense	distal	-5	no	2.230	2.341	EPSD	COSMIC;GDSC	1.787	Up-regulation
AGC_RSK_RSKp90_RPS6KA1_ST	P49841	GSK3B	Q15418	RPS6KA1	T390	Q385P	385	Missense	distal	-5	no	1.859	1.906	EPSD	COSMIC	1.787	Up-regulation
AGC_RSK_RSKp90_RPS6KA1_ST	P49841	GSK3B	Q15418	RPS6KA1	T390	P391L	391	Missense	proximal	1	no	1.859	1.907	EPSD	COSMIC	1.787	Up-regulation
AGC_RSK_RSKp90_RPS6KA1_ST	P49841	GSK3B	Q15418	RPS6KA1	T390	A397V	397	Missense	distal	7	no	1.859	2.090	EPSD	COSMIC;CCLE	1.787	Up-regulation
AGC_RSK_RSKp90_RPS6KA1_ST	Q9H6Z4	RANBP3	Q15418	RPS6KA1	S72	P79S	79	Missense	distal	7	no	2.294	2.192	EPSD	COSMIC	1.787	Down-regulation
AGC_RSK_RSKp90_RPS6KA1_ST	Q9H6Z4	RANBP3	Q15418	RPS6KA1	S72	S72R	72	Missense	central	0	yes	2.294	0.000	EPSD	COSMIC	1.787	Loss
AGC_RSK_RSKp90_RPS6KA1_ST	Q9H6Z4	RANBP3	Q15418	RPS6KA1	S72	S72G	72	Missense	central	0	yes	2.294	0.000	EPSD	COSMIC	1.787	Loss
AGC_RSK_RSKp90_RPS6KA1_ST	Q9H6Z4	RANBP3	Q15418	RPS6KA1	T75	S72R	72	Missense	distal	-3	no	1.543	1.947	EPSD	COSMIC	1.787	Gain
AGC_RSK_RSKp90_RPS6KA1_ST	Q9H6Z4	RANBP3	Q15418	RPS6KA1	S126	K120R	120	Missense	distal	-6	no	1.840	0.945	PhosphoSitePlus	COSMIC	1.787	Loss
AGC_RSK_RSKp90_RPS6KA1_ST	Q9H6Z4	RANBP3	Q15418	RPS6KA1	T194	S191I	191	Missense	distal	-3	no	2.298	2.575	EPSD	COSMIC	1.787	Up-regulation
AGC_RSK_RSKp90_RPS6KA1_ST	Q9H6Z4	RANBP3	Q15418	RPS6KA1	T194	N195S	195	Missense	proximal	1	no	2.298	2.269	EPSD	COSMIC	1.787	Down-regulation
AGC_RSK_RSKp90_RPS6KA1_ST	Q9H6Z4	RANBP3	Q15418	RPS6KA1	T377	K383T	383	Missense	distal	6	no	2.051	2.032	EPSD	COSMIC;CCLE	1.787	Down-regulation
AGC_RSK_RSKp90_RPS6KA1_ST	Q9H6Z4	RANBP3	Q15418	RPS6KA1	T377	A370T	370	Missense	distal	-7	no	2.051	2.046	EPSD	COSMIC	1.787	Down-regulation
AGC_RSK_RSKp90_RPS6KA1_ST	Q9H6Z4	RANBP3	Q15418	RPS6KA1	T377	K378T	378	Missense	proximal	1	no	2.051	2.006	EPSD	COSMIC	1.787	Down-regulation
AGC_RSK_RSKp90_RPS6KA1_ST	Q9H6Z4	RANBP3	Q15418	RPS6KA1	S533	E527G	527	Missense	distal	-6	no	1.423	1.911	EPSD	COSMIC	1.787	Gain
AGC_RSK_RSKp90_RPS6KA1_ST	P30305	CDC25B	Q15418	RPS6KA1	T54	P51L	51	Missense	distal	-3	no	1.433	2.019	EPSD	COSMIC	1.787	Gain
AGC_RSK_RSKp90_RPS6KA1_ST	P30305	CDC25B	Q15418	RPS6KA1	T54	A48T	48	Missense	distal	-6	no	1.433	1.859	EPSD	COSMIC	1.787	Gain
AGC_RSK_RSKp90_RPS6KA1_ST	P30305	CDC25B	Q15418	RPS6KA1	S67	E68K	68	Missense	proximal	1	no	2.025	2.069	EPSD	COSMIC	1.787	Up-regulation
AGC_RSK_RSKp90_RPS6KA1_ST	P30305	CDC25B	Q15418	RPS6KA1	S67	Q73H	73	Missense	distal	6	no	2.025	2.099	EPSD	COSMIC	1.787	Up-regulation
AGC_RSK_RSKp90_RPS6KA1_ST	P30305	CDC25B	Q15418	RPS6KA1	S91	R93W	93	Missense	proximal	2	no	2.641	2.581	EPSD	COSMIC	1.787	Down-regulation
AGC_RSK_RSKp90_RPS6KA1_ST	P30305	CDC25B	Q15418	RPS6KA1	S91	S89P	89	Missense	proximal	-2	no	2.641	2.651	EPSD	COSMIC	1.787	Up-regulation
AGC_RSK_RSKp90_RPS6KA1_ST	P30305	CDC25B	Q15418	RPS6KA1	S229	S230F	230	Missense	proximal	1	no	3.059	3.121	EPSD	COSMIC	1.787	Up-regulation
AGC_RSK_RSKp90_RPS6KA1_ST	P30305	CDC25B	Q15418	RPS6KA1	T265	G270R	270	Missense	distal	5	no	1.373	1.812	EPSD	COSMIC	1.787	Gain
AGC_RSK_RSKp90_RPS6KA1_ST	P30305	CDC25B	Q15418	RPS6KA1	S313	R320G	320	Missense	distal	7	no	2.414	2.473	EPSD	COSMIC	1.787	Up-regulation
AGC_RSK_RSKp90_RPS6KA1_ST	P30305	CDC25B	Q15418	RPS6KA1	S313	C315W	315	Missense	proximal	2	no	2.414	2.245	EPSD	COSMIC;GDSC	1.787	Down-regulation
AGC_RSK_RSKp90_RPS6KA1_ST	P30305	CDC25B	Q15418	RPS6KA1	S313	S313R	313	Missense	central	0	yes	2.414	0.000	EPSD	COSMIC	1.787	Loss
AGC_RSK_RSKp90_RPS6KA1_ST	P30305	CDC25B	Q15418	RPS6KA1	S313	R317W	317	Missense	distal	4	no	2.414	2.425	EPSD	COSMIC	1.787	Up-regulation
AGC_RSK_RSKp90_RPS6KA1_ST	P30305	CDC25B	Q15418	RPS6KA1	S470	E464G	464	Missense	distal	-6	no	1.307	1.795	EPSD	COSMIC	1.787	Gain
AGC_RSK_RSKp90_RPS6KA1_ST	P30307	CDC25C	Q15418	RPS6KA1	S216	S216L	216	Missense	central	0	yes	2.845	0.000	EPSD	COSMIC	1.787	Loss
AGC_RSK_RSKp90_RPS6KA1_ST	P30307	CDC25C	Q15418	RPS6KA1	S216	G210R	210	Missense	distal	-6	no	2.845	1.937	EPSD	COSMIC	1.787	Down-regulation
AGC_RSK_RSKp90_RPS6KA1_ST	P30307	CDC25C	Q15418	RPS6KA1	T261	G255V	255	Missense	distal	-6	no	1.934	1.079	EPSD	COSMIC	1.787	Loss
AGC_RSK_RSKp90_RPS6KA1_ST	P30307	CDC25C	Q15418	RPS6KA1	T261	D266H	266	Missense	distal	5	no	1.934	1.859	EPSD	COSMIC	1.787	Down-regulation
AGC_RSK_RSKp90_RPS6KA1_ST	P30307	CDC25C	Q15418	RPS6KA1	T261	L264R	264	Missense	distal	3	no	1.934	1.761	EPSD	COSMIC	1.787	Loss
AGC_RSK_RSKp90_RPS6KA1_ST	Q8TB45	DEPTOR	Q15418	RPS6KA1	S235	E233K	233	Missense	proximal	-2	no	1.780	1.814	EPSD	COSMIC	1.787	Gain
AGC_RSK_RSKp90_RPS6KA1_ST	Q8TB45	DEPTOR	Q15418	RPS6KA1	T259	S260I	260	Missense	proximal	1	no	2.132	2.266	EPSD	COSMIC	1.787	Up-regulation
AGC_RSK_RSKp90_RPS6KA1_ST	Q8TB45	DEPTOR	Q15418	RPS6KA1	T259	R256W	256	Missense	distal	-3	no	2.132	1.694	EPSD	COSMIC	1.787	Loss
AGC_RSK_RSKp90_RPS6KA1_ST	P49815	TSC2	Q15418	RPS6KA1	S311	G305E	305	Missense	distal	-6	no	1.873	1.386	EPSD	COSMIC	1.787	Loss
AGC_RSK_RSKp90_RPS6KA1_ST	P49815	TSC2	Q15418	RPS6KA1	S311	A306T	306	Missense	distal	-5	no	1.873	2.052	EPSD	COSMIC	1.787	Up-regulation
AGC_RSK_RSKp90_RPS6KA1_ST	P49815	TSC2	Q15418	RPS6KA1	S311	Y310C	310	Missense	proximal	-1	no	1.873	1.911	EPSD	COSMIC	1.787	Up-regulation
AGC_RSK_RSKp90_RPS6KA1_ST	P49815	TSC2	Q15418	RPS6KA1	S311	P316L	316	Missense	distal	5	no	1.873	1.861	EPSD	COSMIC	1.787	Down-regulation
AGC_RSK_RSKp90_RPS6KA1_ST	P49815	TSC2	Q15418	RPS6KA1	S311	S311Y	311	Missense	central	0	yes	1.873	0.000	EPSD	COSMIC	1.787	Loss
AGC_RSK_RSKp90_RPS6KA1_ST	P49815	TSC2	Q15418	RPS6KA1	S311	G305V	305	Missense	distal	-6	no	1.873	1.017	EPSD	COSMIC	1.787	Loss
AGC_RSK_RSKp90_RPS6KA1_ST	P49815	TSC2	Q15418	RPS6KA1	S311	A306S	306	Missense	distal	-5	no	1.873	1.852	EPSD	COSMIC	1.787	Down-regulation
AGC_RSK_RSKp90_RPS6KA1_ST	P49815	TSC2	Q15418	RPS6KA1	S609	R611Q	611	Missense	proximal	2	no	1.958	1.723	EPSD	COSMIC	1.787	Loss
AGC_RSK_RSKp90_RPS6KA1_ST	P49815	TSC2	Q15418	RPS6KA1	S609	R611W	611	Missense	proximal	2	no	1.958	1.899	EPSD	COSMIC	1.787	Down-regulation
AGC_RSK_RSKp90_RPS6KA1_ST	P49815	TSC2	Q15418	RPS6KA1	S609	A614S	614	Missense	distal	5	no	1.958	1.911	EPSD	COSMIC	1.787	Down-regulation
AGC_RSK_RSKp90_RPS6KA1_ST	P49815	TSC2	Q15418	RPS6KA1	S609	T603I	603	Missense	distal	-6	no	1.958	1.522	EPSD	COSMIC	1.787	Loss
AGC_RSK_RSKp90_RPS6KA1_ST	P49815	TSC2	Q15418	RPS6KA1	S609	R611P	611	Missense	proximal	2	no	1.958	1.985	EPSD	COSMIC	1.787	Up-regulation
AGC_RSK_RSKp90_RPS6KA1_ST	P49815	TSC2	Q15418	RPS6KA1	S609	I606F	606	Missense	distal	-3	no	1.958	1.687	EPSD	COSMIC	1.787	Loss
AGC_RSK_RSKp90_RPS6KA1_ST	P49815	TSC2	Q15418	RPS6KA1	S609	D616N	616	Missense	distal	7	no	1.958	1.971	EPSD	COSMIC	1.787	Up-regulation
AGC_RSK_RSKp90_RPS6KA1_ST	P49815	TSC2	Q15418	RPS6KA1	T927	D925Y	925	Missense	proximal	-2	no	1.808	1.803	EPSD	COSMIC	1.787	Down-regulation
AGC_RSK_RSKp90_RPS6KA1_ST	P49815	TSC2	Q15418	RPS6KA1	T927	E929D	929	Missense	proximal	2	no	1.808	1.681	EPSD	COSMIC	1.787	Loss
AGC_RSK_RSKp90_RPS6KA1_ST	P49815	TSC2	Q15418	RPS6KA1	T927	P928S	928	Missense	proximal	1	no	1.808	1.762	EPSD	COSMIC	1.787	Loss
AGC_RSK_RSKp90_RPS6KA1_ST	P49815	TSC2	Q15418	RPS6KA1	T927	P928L	928	Missense	proximal	1	no	1.808	1.856	EPSD	COSMIC	1.787	Up-regulation
AGC_RSK_RSKp90_RPS6KA1_ST	P49815	TSC2	Q15418	RPS6KA1	T927	D926H	926	Missense	proximal	-1	no	1.808	1.760	EPSD	COSMIC	1.787	Loss
AGC_RSK_RSKp90_RPS6KA1_ST	P49815	TSC2	Q15418	RPS6KA1	T927	S932N	932	Missense	distal	5	no	1.808	1.716	EPSD	COSMIC	1.787	Loss
AGC_RSK_RSKp90_RPS6KA1_ST	P49815	TSC2	Q15418	RPS6KA1	T927	T927I	927	Missense	central	0	yes	1.808	0.000	EPSD	COSMIC	1.787	Loss
AGC_RSK_RSKp90_RPS6KA1_ST	P49815	TSC2	Q15418	RPS6KA1	S932	D926H	926	Missense	distal	-6	no	1.365	1.812	EPSD	COSMIC	1.787	Gain
AGC_RSK_RSKp90_RPS6KA1_ST	P49815	TSC2	Q15418	RPS6KA1	S999	S1002L	1002	Missense	distal	3	no	1.893	2.021	EPSD	COSMIC	1.787	Up-regulation
AGC_RSK_RSKp90_RPS6KA1_ST	P49815	TSC2	Q15418	RPS6KA1	S999	T993M	993	Missense	distal	-6	no	1.893	1.213	EPSD	COSMIC	1.787	Loss
AGC_RSK_RSKp90_RPS6KA1_ST	P49815	TSC2	Q15418	RPS6KA1	S999	S999L	999	Missense	central	0	yes	1.893	0.000	EPSD	COSMIC	1.787	Loss
AGC_RSK_RSKp90_RPS6KA1_ST	P49815	TSC2	Q15418	RPS6KA1	S999	S999P	999	Missense	central	0	yes	1.893	0.000	EPSD	COSMIC	1.787	Loss
AGC_RSK_RSKp90_RPS6KA1_ST	P49815	TSC2	Q15418	RPS6KA1	S1097	S1094L	1094	Missense	distal	-3	no	2.532	3.019	EPSD	COSMIC	1.787	Up-regulation
AGC_RSK_RSKp90_RPS6KA1_ST	P49815	TSC2	Q15418	RPS6KA1	S1097	G1099W	1099	Missense	proximal	2	no	2.532	2.467	EPSD	COSMIC	1.787	Down-regulation
AGC_RSK_RSKp90_RPS6KA1_ST	P49815	TSC2	Q15418	RPS6KA1	S1097	E1093K	1093	Missense	distal	-4	no	2.532	2.519	EPSD	COSMIC	1.787	Down-regulation
AGC_RSK_RSKp90_RPS6KA1_ST	P49815	TSC2	Q15418	RPS6KA1	S1097	S1095I	1095	Missense	proximal	-2	no	2.532	2.535	EPSD	COSMIC	1.787	Up-regulation
AGC_RSK_RSKp90_RPS6KA1_ST	P49815	TSC2	Q15418	RPS6KA1	S1097	S1097C	1097	Missense	central	0	yes	2.532	0.000	EPSD	COSMIC	1.787	Loss
AGC_RSK_RSKp90_RPS6KA1_ST	P49815	TSC2	Q15418	RPS6KA1	S1337	S1334C	1334	Missense	distal	-3	no	2.255	2.008	EPSD	COSMIC	1.787	Down-regulation
AGC_RSK_RSKp90_RPS6KA1_ST	P49815	TSC2	Q15418	RPS6KA1	S1337	S1341F	1341	Missense	distal	4	no	2.255	2.282	EPSD	COSMIC	1.787	Up-regulation
AGC_RSK_RSKp90_RPS6KA1_ST	P49815	TSC2	Q15418	RPS6KA1	S1337	A1332V	1332	Missense	distal	-5	no	2.255	2.430	EPSD	COSMIC	1.787	Up-regulation
AGC_RSK_RSKp90_RPS6KA1_ST	P49815	TSC2	Q15418	RPS6KA1	S1337	T1330M	1330	Missense	distal	-7	no	2.255	2.267	EPSD	COSMIC	1.787	Up-regulation
AGC_RSK_RSKp90_RPS6KA1_ST	P49815	TSC2	Q15418	RPS6KA1	S1337	E1344D	1344	Missense	distal	7	no	2.255	2.305	EPSD	COSMIC	1.787	Up-regulation
AGC_RSK_RSKp90_RPS6KA1_ST	P49815	TSC2	Q15418	RPS6KA1	S1337	S1334R	1334	Missense	distal	-3	no	2.255	2.659	EPSD	COSMIC	1.787	Up-regulation
AGC_RSK_RSKp90_RPS6KA1_ST	P49815	TSC2	Q15418	RPS6KA1	S1337	R1335Q	1335	Missense	proximal	-2	no	2.255	2.330	EPSD	COSMIC	1.787	Up-regulation
AGC_RSK_RSKp90_RPS6KA1_ST	P49815	TSC2	Q15418	RPS6KA1	S1338	S1334C	1334	Missense	distal	-4	no	1.778	1.852	EPSD	COSMIC	1.787	Gain
AGC_RSK_RSKp90_RPS6KA1_ST	P49815	TSC2	Q15418	RPS6KA1	S1338	S1341F	1341	Missense	distal	3	no	1.778	1.837	EPSD	COSMIC	1.787	Gain
AGC_RSK_RSKp90_RPS6KA1_ST	P49815	TSC2	Q15418	RPS6KA1	S1338	S1334R	1334	Missense	distal	-4	no	1.778	1.915	EPSD	COSMIC	1.787	Gain
AGC_RSK_RSKp90_RPS6KA1_ST	P49815	TSC2	Q15418	RPS6KA1	S1364	S1365L	1365	Missense	proximal	1	no	2.532	2.626	EPSD	COSMIC	1.787	Up-regulation
AGC_RSK_RSKp90_RPS6KA1_ST	P49815	TSC2	Q15418	RPS6KA1	S1364	V1363M	1363	Missense	proximal	-1	no	2.532	2.471	EPSD	COSMIC	1.787	Down-regulation
AGC_RSK_RSKp90_RPS6KA1_ST	P49815	TSC2	Q15418	RPS6KA1	S1364	R1361Q	1361	Missense	distal	-3	no	2.532	2.122	EPSD	COSMIC	1.787	Down-regulation
AGC_RSK_RSKp90_RPS6KA1_ST	P49815	TSC2	Q15418	RPS6KA1	S1364	G1367S	1367	Missense	distal	3	no	2.532	2.480	EPSD	COSMIC	1.787	Down-regulation
AGC_RSK_RSKp90_RPS6KA1_ST	P49815	TSC2	Q15418	RPS6KA1	S1364	S1364F	1364	Missense	central	0	yes	2.532	0.000	EPSD	COSMIC	1.787	Loss
AGC_RSK_RSKp90_RPS6KA1_ST	P49815	TSC2	Q15418	RPS6KA1	S1364	P1358H	1358	Missense	distal	-6	no	2.532	2.754	EPSD	COSMIC	1.787	Up-regulation
AGC_RSK_RSKp90_RPS6KA1_ST	P49815	TSC2	Q15418	RPS6KA1	S1364	S1371R	1371	Missense	distal	7	no	2.532	2.640	EPSD	COSMIC	1.787	Up-regulation
AGC_RSK_RSKp90_RPS6KA1_ST	P49815	TSC2	Q15418	RPS6KA1	S1364	S1364L	1364	Missense	central	0	yes	2.532	0.000	EPSD	COSMIC	1.787	Loss
AGC_RSK_RSKp90_RPS6KA1_ST	P49815	TSC2	Q15418	RPS6KA1	S1427	S1433L	1433	Missense	distal	6	no	2.187	2.086	EPSD	COSMIC	1.787	Down-regulation
AGC_RSK_RSKp90_RPS6KA1_ST	P49815	TSC2	Q15418	RPS6KA1	S1427	A1429S	1429	Missense	proximal	2	no	2.187	2.381	EPSD	COSMIC;GDSC	1.787	Up-regulation
AGC_RSK_RSKp90_RPS6KA1_ST	P49815	TSC2	Q15418	RPS6KA1	S1427	A1429V	1429	Missense	proximal	2	no	2.187	2.496	EPSD	COSMIC	1.787	Up-regulation
AGC_RSK_RSKp90_RPS6KA1_ST	P49815	TSC2	Q15418	RPS6KA1	S1427	S1427R	1427	Missense	central	0	yes	2.187	0.000	EPSD	COSMIC	1.787	Loss
AGC_RSK_RSKp90_RPS6KA1_ST	P49815	TSC2	Q15418	RPS6KA1	S1427	S1431C	1431	Missense	distal	4	no	2.187	2.205	EPSD	COSMIC	1.787	Up-regulation
AGC_RSK_RSKp90_RPS6KA1_ST	P49815	TSC2	Q15418	RPS6KA1	S1427	S1420C	1420	Missense	distal	-7	no	2.187	2.130	EPSD	COSMIC	1.787	Down-regulation
AGC_RSK_RSKp90_RPS6KA1_ST	P49815	TSC2	Q15418	RPS6KA1	S1427	S1431N	1431	Missense	distal	4	no	2.187	2.188	EPSD	COSMIC	1.787	Up-regulation
AGC_RSK_RSKp90_RPS6KA1_ST	P49815	TSC2	Q15418	RPS6KA1	S1466	S1464F	1464	Missense	proximal	-2	no	3.004	3.015	EPSD	COSMIC	1.787	Up-regulation
AGC_RSK_RSKp90_RPS6KA1_ST	P49815	TSC2	Q15418	RPS6KA1	S1466	S1464Y	1464	Missense	proximal	-2	no	3.004	3.018	EPSD	COSMIC	1.787	Up-regulation
AGC_RSK_RSKp90_RPS6KA1_ST	P49815	TSC2	Q15418	RPS6KA1	S1466	Y1461H	1461	Missense	distal	-5	no	3.004	2.951	EPSD	COSMIC	1.787	Down-regulation
AGC_RSK_RSKp90_RPS6KA1_ST	P49815	TSC2	Q15418	RPS6KA1	S1466	R1459Q	1459	Missense	distal	-7	no	3.004	2.953	EPSD	COSMIC	1.787	Down-regulation
AGC_RSK_RSKp90_RPS6KA1_ST	P49815	TSC2	Q15418	RPS6KA1	S1466	I1463N	1463	Missense	distal	-3	no	3.004	2.628	EPSD	COSMIC	1.787	Down-regulation
AGC_RSK_RSKp90_RPS6KA1_ST	P49815	TSC2	Q15418	RPS6KA1	S1466	R1471M	1471	Missense	distal	5	no	3.004	2.819	EPSD	COSMIC	1.787	Down-regulation
AGC_RSK_RSKp90_RPS6KA1_ST	P49815	TSC2	Q15418	RPS6KA1	S1466	R1470H	1470	Missense	distal	4	no	3.004	3.045	EPSD	COSMIC	1.787	Up-regulation
AGC_RSK_RSKp90_RPS6KA1_ST	P49815	TSC2	Q15418	RPS6KA1	S1466	D1465N	1465	Missense	proximal	-1	no	3.004	3.015	EPSD	COSMIC	1.787	Up-regulation
AGC_RSK_RSKp90_RPS6KA1_ST	P49815	TSC2	Q15418	RPS6KA1	S1466	P1468T	1468	Missense	proximal	2	no	3.004	2.924	EPSD	COSMIC	1.787	Down-regulation
AGC_RSK_RSKp90_RPS6KA1_ST	P49815	TSC2	Q15418	RPS6KA1	S1466	T1462I	1462	Missense	distal	-4	no	3.004	2.908	EPSD	COSMIC	1.787	Down-regulation
AGC_RSK_RSKp90_RPS6KA1_ST	P49815	TSC2	Q15418	RPS6KA1	S1466	S1464C	1464	Missense	proximal	-2	no	3.004	3.026	EPSD	COSMIC	1.787	Up-regulation
AGC_RSK_RSKp90_RPS6KA1_ST	P49815	TSC2	Q15418	RPS6KA1	S1761	A1759G	1759	Missense	proximal	-2	no	1.738	1.829	EPSD	COSMIC	1.787	Gain
AGC_RSK_RSKp90_RPS6KA1_ST	P49815	TSC2	Q15418	RPS6KA1	S1761	E1756D	1756	Missense	distal	-5	no	1.738	1.997	EPSD	COSMIC	1.787	Gain
AGC_RSK_RSKp90_RPS6KA1_ST	P49815	TSC2	Q15418	RPS6KA1	S1761	A1759V	1759	Missense	proximal	-2	no	1.738	1.796	EPSD	COSMIC	1.787	Gain
AGC_RSK_RSKp90_RPS6KA1_ST	O00418	EEF2K	Q15418	RPS6KA1	S241	S243P	243	Missense	proximal	2	no	1.778	1.956	EPSD	COSMIC	1.787	Gain
AGC_RSK_RSKp90_RPS6KA1_ST	O00418	EEF2K	Q15418	RPS6KA1	S241	S243F	243	Missense	proximal	2	no	1.778	1.850	EPSD	COSMIC	1.787	Gain
AGC_RSK_RSKp90_RPS6KA1_ST	O00418	EEF2K	Q15418	RPS6KA1	T340	L343P	343	Missense	distal	3	no	1.985	1.921	EPSD	COSMIC	1.787	Down-regulation
AGC_RSK_RSKp90_RPS6KA1_ST	O00418	EEF2K	Q15418	RPS6KA1	S359	T364N	364	Missense	distal	5	no	2.297	2.206	EPSD	COSMIC	1.787	Down-regulation
AGC_RSK_RSKp90_RPS6KA1_ST	O00418	EEF2K	Q15418	RPS6KA1	S359	E355K	355	Missense	distal	-4	no	2.297	2.284	EPSD	COSMIC	1.787	Down-regulation
AGC_RSK_RSKp90_RPS6KA1_ST	O00418	EEF2K	Q15418	RPS6KA1	T364	T364N	364	Missense	central	0	yes	2.078	0.000	EPSD	COSMIC	1.787	Loss
AGC_RSK_RSKp90_RPS6KA1_ST	O00418	EEF2K	Q15418	RPS6KA1	S377	E383D	383	Missense	distal	6	no	2.448	2.277	EPSD	COSMIC	1.787	Down-regulation
AGC_RSK_RSKp90_RPS6KA1_ST	O00418	EEF2K	Q15418	RPS6KA1	S377	S377L	377	Missense	central	0	yes	2.448	0.000	EPSD	COSMIC	1.787	Loss
AGC_RSK_RSKp90_RPS6KA1_ST	O00418	EEF2K	Q15418	RPS6KA1	S377	P375S	375	Missense	proximal	-2	no	2.448	2.438	EPSD	COSMIC	1.787	Down-regulation
AGC_RSK_RSKp90_RPS6KA1_ST	O00418	EEF2K	Q15418	RPS6KA1	S380	S377L	377	Missense	distal	-3	no	1.596	2.084	EPSD	COSMIC	1.787	Gain
AGC_RSK_RSKp90_RPS6KA1_ST	O00418	EEF2K	Q15418	RPS6KA1	S478	S478F	478	Missense	central	0	yes	1.938	0.000	EPSD	COSMIC	1.787	Loss
AGC_RSK_RSKp90_RPS6KA1_ST	O00418	EEF2K	Q15418	RPS6KA1	S478	R480W	480	Missense	proximal	2	no	1.938	1.878	EPSD	COSMIC	1.787	Down-regulation
AGC_RSK_RSKp90_RPS6KA1_ST	O00418	EEF2K	Q15418	RPS6KA1	S478	G476C	476	Missense	proximal	-2	no	1.938	1.894	EPSD	COSMIC	1.787	Down-regulation
AGC_RSK_RSKp90_RPS6KA1_ST	P03372	ESR1	Q15418	RPS6KA1	S46	S47T	47	Missense	proximal	1	no	1.897	1.971	EPSD	COSMIC	1.787	Up-regulation
AGC_RSK_RSKp90_RPS6KA1_ST	P03372	ESR1	Q15418	RPS6KA1	S46	A50T	50	Missense	distal	4	no	1.897	1.914	EPSD	COSMIC	1.787	Up-regulation
AGC_RSK_RSKp90_RPS6KA1_ST	P03372	ESR1	Q15418	RPS6KA1	S46	K48N	48	Missense	proximal	2	no	1.897	1.763	EPSD	COSMIC	1.787	Loss
AGC_RSK_RSKp90_RPS6KA1_ST	P03372	ESR1	Q15418	RPS6KA1	S46	D45N	45	Missense	proximal	-1	no	1.897	1.908	EPSD	COSMIC	1.787	Up-regulation
AGC_RSK_RSKp90_RPS6KA1_ST	P03372	ESR1	Q15418	RPS6KA1	S46	P49S	49	Missense	distal	3	no	1.897	1.833	EPSD	COSMIC	1.787	Down-regulation
AGC_RSK_RSKp90_RPS6KA1_ST	P03372	ESR1	Q15418	RPS6KA1	S47	Y54C	54	Missense	distal	7	no	2.612	2.688	EPSD	COSMIC	1.787	Up-regulation
AGC_RSK_RSKp90_RPS6KA1_ST	P03372	ESR1	Q15418	RPS6KA1	S47	A50T	50	Missense	distal	3	no	2.612	2.690	EPSD	COSMIC	1.787	Up-regulation
AGC_RSK_RSKp90_RPS6KA1_ST	P03372	ESR1	Q15418	RPS6KA1	S47	K48N	48	Missense	proximal	1	no	2.612	2.520	EPSD	COSMIC	1.787	Down-regulation
AGC_RSK_RSKp90_RPS6KA1_ST	P03372	ESR1	Q15418	RPS6KA1	S47	D45N	45	Missense	proximal	-2	no	2.612	2.636	EPSD	COSMIC	1.787	Up-regulation
AGC_RSK_RSKp90_RPS6KA1_ST	P03372	ESR1	Q15418	RPS6KA1	S47	P49S	49	Missense	proximal	2	no	2.612	2.433	EPSD	COSMIC	1.787	Down-regulation
AGC_RSK_RSKp90_RPS6KA1_ST	P03372	ESR1	Q15418	RPS6KA1	S118	L117Q	117	Missense	proximal	-1	no	1.712	1.793	EPSD	COSMIC	1.787	Gain
AGC_RSK_RSKp90_RPS6KA1_ST	P03372	ESR1	Q15418	RPS6KA1	S167	G172R	172	Missense	distal	5	no	1.478	1.917	PhosphoSitePlus	COSMIC	1.787	Gain
AGC_RSK_RSKp90_RPS6KA1_ST	P03372	ESR1	Q15418	RPS6KA1	S329	P325L	325	Missense	distal	-4	no	2.028	2.096	EPSD	COSMIC	1.787	Up-regulation
AGC_RSK_RSKp90_RPS6KA1_ST	P03372	ESR1	Q15418	RPS6KA1	S329	D332V	332	Missense	distal	3	no	2.028	2.031	EPSD	COSMIC	1.787	Up-regulation
AGC_RSK_RSKp90_RPS6KA1_ST	P03372	ESR1	Q15418	RPS6KA1	S329	S329Y	329	Missense	central	0	yes	2.028	0.000	EPSD	COSMIC	1.787	Loss
AGC_RSK_RSKp90_RPS6KA1_ST	P03372	ESR1	Q15418	RPS6KA1	S329	P325S	325	Missense	distal	-4	no	2.028	1.837	EPSD	COSMIC	1.787	Down-regulation
AGC_RSK_RSKp90_RPS6KA1_ST	P03372	ESR1	Q15418	RPS6KA1	S329	P333T	333	Missense	distal	4	no	2.028	2.030	EPSD	COSMIC	1.787	Up-regulation
AGC_RSK_RSKp90_RPS6KA1_ST	P03372	ESR1	Q15418	RPS6KA1	S329	P324S	324	Missense	distal	-5	no	2.028	1.893	EPSD	COSMIC	1.787	Down-regulation
AGC_RSK_RSKp90_RPS6KA1_ST	P03372	ESR1	Q15418	RPS6KA1	T485	K481N	481	Missense	distal	-4	no	1.859	1.676	EPSD	COSMIC	1.787	Loss
AGC_RSK_RSKp90_RPS6KA1_ST	P03372	ESR1	Q15418	RPS6KA1	T485	L486F	486	Missense	proximal	1	no	1.859	1.826	EPSD	COSMIC	1.787	Down-regulation
AGC_RSK_RSKp90_RPS6KA1_ST	P03372	ESR1	Q15418	RPS6KA1	T485	A491T	491	Missense	distal	6	no	1.859	1.796	EPSD	COSMIC	1.787	Down-regulation
AGC_RSK_RSKp90_RPS6KA1_ST	P03372	ESR1	Q15418	RPS6KA1	T485	D484Y	484	Missense	proximal	-1	no	1.859	1.890	EPSD	COSMIC	1.787	Up-regulation
AGC_RSK_RSKp90_RPS6KA1_ST	P03372	ESR1	Q15418	RPS6KA1	T485	V478I	478	Missense	distal	-7	no	1.859	1.857	EPSD	COSMIC	1.787	Down-regulation
AGC_RSK_RSKp90_RPS6KA1_ST	P03372	ESR1	Q15418	RPS6KA1	T485	M490I	490	Missense	distal	5	no	1.859	1.894	EPSD	COSMIC	1.787	Up-regulation
AGC_RSK_RSKp90_RPS6KA1_ST	P03372	ESR1	Q15418	RPS6KA1	T485	L489V	489	Missense	distal	4	no	1.859	1.771	EPSD	COSMIC	1.787	Loss
AGC_RSK_RSKp90_RPS6KA1_ST	P62753	RPS6	Q15418	RPS6KA1	S82	L75M	75	Missense	distal	-7	no	2.557	2.578	EPSD	COSMIC	1.787	Up-regulation
AGC_RSK_RSKp90_RPS6KA1_ST	P62753	RPS6	Q15418	RPS6KA1	S107	V112I	112	Missense	distal	5	no	2.242	2.168	EPSD	COSMIC	1.787	Down-regulation
AGC_RSK_RSKp90_RPS6KA1_ST	P62753	RPS6	Q15418	RPS6KA1	S148	R142H	142	Missense	distal	-6	no	1.004	1.806	EPSD	COSMIC	1.787	Gain
AGC_RSK_RSKp90_RPS6KA1_ST	P67809	YBX1	Q15418	RPS6KA1	T25	A19P	19	Missense	distal	-6	no	2.426	2.495	EPSD	COSMIC	1.787	Up-regulation
AGC_RSK_RSKp90_RPS6KA1_ST	O14757	CHEK1	Q15418	RPS6KA1	T330	S326F	326	Missense	distal	-4	no	2.261	2.427	EPSD	COSMIC	1.787	Up-regulation
AGC_RSK_RSKp90_RPS6KA1_ST	O14757	CHEK1	Q15418	RPS6KA1	T330	P332L	332	Missense	proximal	2	no	2.261	2.078	EPSD	COSMIC	1.787	Down-regulation
AGC_RSK_RSKp90_RPS6KA1_ST	O75030	MITF	Q15418	RPS6KA1	S409	L406H	406	Missense	distal	-3	no	2.392	1.889	PhosphoSitePlus	COSMIC	1.787	Down-regulation
AGC_RSK_RSKp90_RPS6KA1_ST	O75030	MITF	Q15418	RPS6KA1	S409	C413F	413	Missense	distal	4	no	2.392	2.402	PhosphoSitePlus	COSMIC	1.787	Up-regulation
AGC_RSK_RSKp90_RPS6KA1_ST	O75030	MITF	Q15418	RPS6KA1	S409	S405I	405	Missense	distal	-4	no	2.392	2.403	PhosphoSitePlus	COSMIC	1.787	Up-regulation
AGC_RSK_RSKp90_RPS6KA1_ST	O75030	MITF	Q15418	RPS6KA1	T410	L406H	406	Missense	distal	-4	no	2.101	1.836	EPSD	COSMIC	1.787	Down-regulation
AGC_RSK_RSKp90_RPS6KA1_ST	O75030	MITF	Q15418	RPS6KA1	T410	C413F	413	Missense	distal	3	no	2.101	2.115	EPSD	COSMIC	1.787	Up-regulation
AGC_RSK_RSKp90_RPS6KA1_ST	O75030	MITF	Q15418	RPS6KA1	T410	S405I	405	Missense	distal	-5	no	2.101	2.103	EPSD	COSMIC	1.787	Up-regulation
AGC_RSK_RSKp90_RPS6KA1_ST	O75030	MITF	Q15418	RPS6KA1	S502	S504F	504	Missense	proximal	2	no	1.928	2.000	EPSD	COSMIC	1.787	Up-regulation
AGC_RSK_RSKp90_RPS6KA1_ST	O75030	MITF	Q15418	RPS6KA1	S502	A507T	507	Missense	distal	5	no	1.928	1.879	EPSD	COSMIC	1.787	Down-regulation
AGC_RSK_RSKp90_RPS6KA1_ST	P21333	FLNA	Q15418	RPS6KA1	S368	A361T	361	Missense	distal	-7	no	3.245	3.240	EPSD	COSMIC	1.787	Down-regulation
AGC_RSK_RSKp90_RPS6KA1_ST	P21333	FLNA	Q15418	RPS6KA1	S368	V372L	372	Missense	distal	4	no	3.245	3.333	EPSD	COSMIC	1.787	Up-regulation
AGC_RSK_RSKp90_RPS6KA1_ST	P21333	FLNA	Q15418	RPS6KA1	S564	R563C	563	Missense	proximal	-1	no	1.563	1.825	EPSD	COSMIC;GDSC;CCLE	1.787	Gain
AGC_RSK_RSKp90_RPS6KA1_ST	P21333	FLNA	Q15418	RPS6KA1	T685	V689I	689	Missense	distal	4	no	1.908	1.967	EPSD	COSMIC	1.787	Up-regulation
AGC_RSK_RSKp90_RPS6KA1_ST	P21333	FLNA	Q15418	RPS6KA1	T885	E888V	888	Missense	distal	3	no	1.777	1.788	EPSD	COSMIC	1.787	Gain
AGC_RSK_RSKp90_RPS6KA1_ST	P21333	FLNA	Q15418	RPS6KA1	T885	G890V	890	Missense	distal	5	no	1.777	2.140	EPSD	COSMIC;CCLE	1.787	Gain
AGC_RSK_RSKp90_RPS6KA1_ST	P21333	FLNA	Q15418	RPS6KA1	T915	T915A	915	Missense	central	0	yes	2.604	0.000	EPSD	COSMIC	1.787	Loss
AGC_RSK_RSKp90_RPS6KA1_ST	P21333	FLNA	Q15418	RPS6KA1	T915	R921Q	921	Missense	distal	6	no	2.604	2.552	EPSD	COSMIC;CCLE	1.787	Down-regulation
AGC_RSK_RSKp90_RPS6KA1_ST	P21333	FLNA	Q15418	RPS6KA1	T915	G917V	917	Missense	proximal	2	no	2.604	2.562	EPSD	COSMIC	1.787	Down-regulation
AGC_RSK_RSKp90_RPS6KA1_ST	P21333	FLNA	Q15418	RPS6KA1	T915	S912L	912	Missense	distal	-3	no	2.604	3.092	EPSD	COSMIC	1.787	Up-regulation
AGC_RSK_RSKp90_RPS6KA1_ST	P21333	FLNA	Q15418	RPS6KA1	T915	V909L	909	Missense	distal	-6	no	2.604	3.291	EPSD	COSMIC	1.787	Up-regulation
AGC_RSK_RSKp90_RPS6KA1_ST	P21333	FLNA	Q15418	RPS6KA1	T915	V920I	920	Missense	distal	5	no	2.604	2.530	EPSD	COSMIC	1.787	Down-regulation
AGC_RSK_RSKp90_RPS6KA1_ST	P21333	FLNA	Q15418	RPS6KA1	T950	V949A	949	Missense	proximal	-1	no	1.969	1.748	EPSD	COSMIC	1.787	Loss
AGC_RSK_RSKp90_RPS6KA1_ST	P21333	FLNA	Q15418	RPS6KA1	S977	K975N	975	Missense	proximal	-2	no	1.897	1.912	EPSD	COSMIC;GDSC;CCLE	1.787	Up-regulation
AGC_RSK_RSKp90_RPS6KA1_ST	P21333	FLNA	Q15418	RPS6KA1	T1558	G1554E	1554	Missense	distal	-4	no	2.077	2.184	EPSD	COSMIC	1.787	Up-regulation
AGC_RSK_RSKp90_RPS6KA1_ST	P21333	FLNA	Q15418	RPS6KA1	T1558	G1559C	1559	Missense	proximal	1	no	2.077	2.165	EPSD	COSMIC	1.787	Up-regulation
AGC_RSK_RSKp90_RPS6KA1_ST	P21333	FLNA	Q15418	RPS6KA1	T1558	G1552V	1552	Missense	distal	-6	no	2.077	1.221	EPSD	COSMIC	1.787	Loss
AGC_RSK_RSKp90_RPS6KA1_ST	P21333	FLNA	Q15418	RPS6KA1	S1812	G1806V	1806	Missense	distal	-6	no	2.967	2.111	EPSD	COSMIC	1.787	Down-regulation
AGC_RSK_RSKp90_RPS6KA1_ST	P21333	FLNA	Q15418	RPS6KA1	S1812	T1805I	1805	Missense	distal	-7	no	2.967	2.933	EPSD	COSMIC	1.787	Down-regulation
AGC_RSK_RSKp90_RPS6KA1_ST	P21333	FLNA	Q15418	RPS6KA1	S1991	R1993W	1993	Missense	proximal	2	no	2.402	2.342	EPSD	COSMIC;GDSC	1.787	Down-regulation
AGC_RSK_RSKp90_RPS6KA1_ST	P21333	FLNA	Q15418	RPS6KA1	S1991	P1989Q	1989	Missense	proximal	-2	no	2.402	2.400	EPSD	COSMIC	1.787	Down-regulation
AGC_RSK_RSKp90_RPS6KA1_ST	P21333	FLNA	Q15418	RPS6KA1	S1991	P1989L	1989	Missense	proximal	-2	no	2.402	2.395	EPSD	COSMIC	1.787	Down-regulation
AGC_RSK_RSKp90_RPS6KA1_ST	P21333	FLNA	Q15418	RPS6KA1	S1991	E1994K	1994	Missense	distal	3	no	2.402	2.467	EPSD	COSMIC	1.787	Up-regulation
AGC_RSK_RSKp90_RPS6KA1_ST	P21333	FLNA	Q15418	RPS6KA1	S1991	P1996T	1996	Missense	distal	5	no	2.402	2.398	EPSD	COSMIC	1.787	Down-regulation
AGC_RSK_RSKp90_RPS6KA1_ST	P21333	FLNA	Q15418	RPS6KA1	S1991	P1996L	1996	Missense	distal	5	no	2.402	2.390	EPSD	COSMIC	1.787	Down-regulation
AGC_RSK_RSKp90_RPS6KA1_ST	P21333	FLNA	Q15418	RPS6KA1	S2158	P2151S	2151	Missense	distal	-7	no	2.121	2.129	EPSD	COSMIC	1.787	Up-regulation
AGC_RSK_RSKp90_RPS6KA1_ST	P21333	FLNA	Q15418	RPS6KA1	S2158	V2156I	2156	Missense	proximal	-2	no	2.121	2.091	EPSD	COSMIC	1.787	Down-regulation
AGC_RSK_RSKp90_RPS6KA1_ST	P21333	FLNA	Q15418	RPS6KA1	S2158	S2163I	2163	Missense	distal	5	no	2.121	2.178	EPSD	COSMIC	1.787	Up-regulation
AGC_RSK_RSKp90_RPS6KA1_ST	P21333	FLNA	Q15418	RPS6KA1	S2158	V2153A	2153	Missense	distal	-5	no	2.121	1.945	EPSD	COSMIC	1.787	Down-regulation
AGC_RSK_RSKp90_RPS6KA1_ST	P21333	FLNA	Q15418	RPS6KA1	T2209	P2204T	2204	Missense	distal	-5	no	2.209	2.274	EPSD	COSMIC	1.787	Up-regulation
AGC_RSK_RSKp90_RPS6KA1_ST	P21333	FLNA	Q15418	RPS6KA1	T2209	V2203A	2203	Missense	distal	-6	no	2.209	2.668	EPSD	COSMIC	1.787	Up-regulation
AGC_RSK_RSKp90_RPS6KA1_ST	P21333	FLNA	Q15418	RPS6KA1	T2209	V2203L	2203	Missense	distal	-6	no	2.209	2.896	EPSD	COSMIC	1.787	Up-regulation
AGC_RSK_RSKp90_RPS6KA1_ST	P21333	FLNA	Q15418	RPS6KA1	T2209	V2203M	2203	Missense	distal	-6	no	2.209	2.414	EPSD	COSMIC	1.787	Up-regulation
AGC_RSK_RSKp90_RPS6KA1_ST	P21333	FLNA	Q15418	RPS6KA1	T2229	G2234E	2234	Missense	distal	5	no	1.730	1.972	EPSD	COSMIC	1.787	Gain
AGC_RSK_RSKp90_RPS6KA1_ST	P21333	FLNA	Q15418	RPS6KA1	S2260	R2264L	2264	Missense	distal	4	no	2.156	2.204	EPSD	COSMIC	1.787	Up-regulation
AGC_RSK_RSKp90_RPS6KA1_ST	P21333	FLNA	Q15418	RPS6KA1	S2260	P2256S	2256	Missense	distal	-4	no	2.156	1.965	EPSD	COSMIC	1.787	Down-regulation
AGC_RSK_RSKp90_RPS6KA1_ST	P21333	FLNA	Q15418	RPS6KA1	S2260	F2259L	2259	Missense	proximal	-1	no	2.156	1.978	EPSD	COSMIC	1.787	Down-regulation
AGC_RSK_RSKp90_RPS6KA1_ST	P21333	FLNA	Q15418	RPS6KA1	S2260	E2265G	2265	Missense	distal	5	no	2.156	1.914	EPSD	COSMIC	1.787	Down-regulation
AGC_RSK_RSKp90_RPS6KA1_ST	P21333	FLNA	Q15418	RPS6KA1	S2343	V2337F	2337	Missense	distal	-6	no	1.721	2.038	EPSD	COSMIC	1.787	Gain
AGC_RSK_RSKp90_RPS6KA1_ST	P21333	FLNA	Q15418	RPS6KA1	S2343	G2344W	2344	Missense	proximal	1	no	1.721	1.869	EPSD	COSMIC	1.787	Gain
AGC_RSK_RSKp90_RPS6KA1_ST	P21333	FLNA	Q15418	RPS6KA1	S2343	V2337I	2337	Missense	distal	-6	no	1.721	2.169	EPSD	COSMIC	1.787	Gain
AGC_RSK_RSKp90_RPS6KA1_ST	P21333	FLNA	Q15418	RPS6KA1	S2414	P2415R	2415	Missense	proximal	1	no	2.574	2.598	EPSD	COSMIC	1.787	Up-regulation
AGC_RSK_RSKp90_RPS6KA1_ST	P21333	FLNA	Q15418	RPS6KA1	S2414	V2420F	2420	Missense	distal	6	no	2.574	2.637	EPSD	COSMIC	1.787	Up-regulation
AGC_RSK_RSKp90_RPS6KA1_ST	P21333	FLNA	Q15418	RPS6KA1	S2414	G2408S	2408	Missense	distal	-6	no	2.574	1.906	EPSD	COSMIC	1.787	Down-regulation
AGC_RSK_RSKp90_RPS6KA1_ST	P21333	FLNA	Q15418	RPS6KA1	S2414	G2413E	2413	Missense	proximal	-1	no	2.574	2.408	EPSD	COSMIC	1.787	Down-regulation
AGC_RSK_RSKp90_RPS6KA1_ST	P21333	FLNA	Q15418	RPS6KA1	S2523	V2522I	2522	Missense	proximal	-1	no	2.291	2.022	EPSD	COSMIC	1.787	Down-regulation
AGC_RSK_RSKp90_RPS6KA1_ST	P21333	FLNA	Q15418	RPS6KA1	S2523	H2528Q	2528	Missense	distal	5	no	2.291	2.437	EPSD	COSMIC	1.787	Up-regulation
AGC_RSK_RSKp90_RPS6KA1_ST	P21333	FLNA	Q15418	RPS6KA1	S2523	H2525P	2525	Missense	proximal	2	no	2.291	2.486	EPSD	COSMIC	1.787	Up-regulation
AGC_RSK_RSKp90_RPS6KA1_ST	P21333	FLNA	Q15418	RPS6KA1	T2579	D2581H	2581	Missense	proximal	2	no	1.953	1.921	EPSD	COSMIC;GDSC	1.787	Down-regulation
AGC_RSK_RSKp90_RPS6KA1_ST	P21333	FLNA	Q15418	RPS6KA1	T2579	V2572I	2572	Missense	distal	-7	no	1.953	1.952	EPSD	COSMIC;GDSC;CCLE	1.787	Down-regulation
AGC_RSK_RSKp90_RPS6KA1_ST	P21333	FLNA	Q15418	RPS6KA1	S2611	Y2618C	2618	Missense	distal	7	no	2.499	2.576	EPSD	COSMIC	1.787	Up-regulation
AGC_RSK_RSKp90_RPS6KA1_ST	P21333	FLNA	Q15418	RPS6KA1	S2611	V2606L	2606	Missense	distal	-5	no	2.499	2.441	EPSD	COSMIC	1.787	Down-regulation
AGC_RSK_RSKp90_RPS6KA1_ST	P21333	FLNA	Q15418	RPS6KA1	T2627	K2623N	2623	Missense	distal	-4	no	2.122	1.940	EPSD	COSMIC	1.787	Down-regulation
AGC_RSK_RSKp90_RPS6KA1_ST	Q53EL6	PDCD4	Q15418	RPS6KA1	S94	T93I	93	Missense	proximal	-1	no	3.119	2.887	EPSD	COSMIC	1.787	Down-regulation
AGC_RSK_RSKp90_RPS6KA1_ST	Q53EL6	PDCD4	Q15418	RPS6KA1	T234	G228W	228	Missense	distal	-6	no	1.853	1.279	EPSD	COSMIC	1.787	Loss
AGC_RSK_RSKp90_RPS6KA1_ST	Q53EL6	PDCD4	Q15418	RPS6KA1	T234	D235Y	235	Missense	proximal	1	no	1.853	1.909	EPSD	COSMIC	1.787	Up-regulation
AGC_RSK_RSKp90_RPS6KA1_ST	Q53EL6	PDCD4	Q15418	RPS6KA1	S313	G307V	307	Missense	distal	-6	no	2.077	1.221	EPSD	COSMIC	1.787	Loss
AGC_RSK_RSKp90_RPS6KA1_ST	Q07889	SOS1	Q15418	RPS6KA1	S403	S401N	401	Missense	proximal	-2	no	2.640	2.683	EPSD	COSMIC	1.787	Up-regulation
AGC_RSK_RSKp90_RPS6KA1_ST	Q07889	SOS1	Q15418	RPS6KA1	S403	R398G	398	Missense	distal	-5	no	2.640	2.844	EPSD	COSMIC	1.787	Up-regulation
AGC_RSK_RSKp90_RPS6KA1_ST	Q07889	SOS1	Q15418	RPS6KA1	S403	Y408H	408	Missense	distal	5	no	2.640	2.439	EPSD	COSMIC	1.787	Down-regulation
AGC_RSK_RSKp90_RPS6KA1_ST	Q07889	SOS1	Q15418	RPS6KA1	S403	C405Y	405	Missense	proximal	2	no	2.640	2.418	EPSD	COSMIC	1.787	Down-regulation
AGC_RSK_RSKp90_RPS6KA1_ST	Q07889	SOS1	Q15418	RPS6KA1	S1134	G1129V	1129	Missense	distal	-5	no	2.053	2.070	PhosphoSitePlus;EPSD	COSMIC	1.787	Up-regulation
AGC_RSK_RSKp90_RPS6KA1_ST	Q07889	SOS1	Q15418	RPS6KA1	S1139	E1146K	1146	Missense	distal	7	no	2.117	2.048	EPSD	COSMIC	1.787	Down-regulation
AGC_RSK_RSKp90_RPS6KA1_ST	Q07889	SOS1	Q15418	RPS6KA1	S1228	V1225A	1225	Missense	distal	-3	no	1.406	1.972	EPSD	COSMIC	1.787	Gain
AGC_RSK_RSKp90_RPS6KA1_ST	Q07889	SOS1	Q15418	RPS6KA1	T1279	P1276L	1276	Missense	distal	-3	no	2.069	2.655	EPSD	COSMIC	1.787	Up-regulation
AGC_RSK_RSKp90_RPS6KA1_ST	P13796	LCP1	Q15418	RPS6KA1	T89	V86F	86	Missense	distal	-3	no	1.653	1.826	EPSD	COSMIC	1.787	Gain
AGC_RSK_RSKp90_RPS6KA1_ST	P13796	LCP1	Q15418	RPS6KA1	T89	S83T	83	Missense	distal	-6	no	1.653	2.350	EPSD	COSMIC	1.787	Gain
AGC_RSK_RSKp90_RPS6KA1_ST	P13796	LCP1	Q15418	RPS6KA1	T89	V86I	86	Missense	distal	-3	no	1.653	2.098	EPSD	COSMIC	1.787	Gain
AGC_RSK_RSKp90_RPS6KA1_ST	P13796	LCP1	Q15418	RPS6KA1	S474	K468N	468	Missense	distal	-6	no	2.365	1.814	EPSD	COSMIC	1.787	Down-regulation
AGC_RSK_RSKp90_RPS6KA1_ST	P13796	LCP1	Q15418	RPS6KA1	S474	A471E	471	Missense	distal	-3	no	2.365	1.996	EPSD	COSMIC;GDSC;CCLE	1.787	Down-regulation
AGC_RSK_RSKp90_RPS6KA1_ST	P13796	LCP1	Q15418	RPS6KA1	S537	K533E	533	Missense	distal	-4	no	1.795	1.808	EPSD	COSMIC	1.787	Up-regulation
AGC_RSK_RSKp90_RPS6KA1_ST	P13796	LCP1	Q15418	RPS6KA1	S537	K542N	542	Missense	distal	5	no	1.795	1.805	EPSD	COSMIC	1.787	Up-regulation
AGC_RSK_RSKp90_RPS6KA1_ST	O14727	APAF1	Q15418	RPS6KA1	S268	R265G	265	Missense	distal	-3	no	2.874	2.133	EPSD;PhosphoSitePlus	COSMIC	1.787	Down-regulation
AGC_RSK_RSKp90_RPS6KA1_ST	O14727	APAF1	Q15418	RPS6KA1	S432	L437I	437	Missense	distal	5	no	2.396	2.463	EPSD	COSMIC	1.787	Up-regulation
AGC_RSK_RSKp90_RPS6KA1_ST	P53355	DAPK1	Q15418	RPS6KA1	S714	R720Q	720	Missense	distal	6	no	2.022	1.970	EPSD	COSMIC	1.787	Down-regulation
AGC_RSK_RSKp90_RPS6KA1_ST	P53355	DAPK1	Q15418	RPS6KA1	S1115	A1117S	1117	Missense	proximal	2	no	2.472	2.665	EPSD	COSMIC;GDSC	1.787	Up-regulation
AGC_RSK_RSKp90_RPS6KA1_ST	P53355	DAPK1	Q15418	RPS6KA1	S1115	E1119D	1119	Missense	distal	4	no	2.472	2.448	EPSD	COSMIC	1.787	Down-regulation
AGC_RSK_RSKp90_RPS6KA1_ST	Q9UBP6	METTL1	Q15418	RPS6KA1	S177	R174L	174	Missense	distal	-3	no	2.614	2.697	EPSD	COSMIC	1.787	Up-regulation
AGC_RSK_RSKp90_RPS6KA1_ST	Q9UBP6	METTL1	Q15418	RPS6KA1	S177	R174Q	174	Missense	distal	-3	no	2.614	2.204	EPSD	COSMIC	1.787	Down-regulation
AGC_RSK_RSKp90_RPS6KA1_ST	P30304	CDC25A	Q15418	RPS6KA1	S320	P322L	322	Missense	proximal	2	no	1.986	1.803	EPSD	COSMIC	1.787	Down-regulation
AGC_RSK_RSKp90_RPS6KA1_ST	P30304	CDC25A	Q15418	RPS6KA1	S320	S320Y	320	Missense	central	0	yes	1.986	0.000	EPSD	COSMIC	1.787	Loss
AGC_RSK_RSKp90_RPS6KA1_ST	P60983	GMFB	Q15418	RPS6KA1	T27	A31V	31	Missense	distal	4	no	2.127	2.077	PhosphoSitePlus	COSMIC;GDSC;CCLE	1.787	Down-regulation
AGC_RSK_RSKp90_RPS6KA1_ST	P60983	GMFB	Q15418	RPS6KA1	T27	R24C	24	Missense	distal	-3	no	2.127	1.476	PhosphoSitePlus	COSMIC	1.787	Loss
AGC_RSK_RSKp90_RPS6KA1_ST	P49427	CDC34	Q15418	RPS6KA1	T186	C191Y	191	Missense	distal	5	no	2.010	2.064	EPSD	COSMIC	1.787	Up-regulation
AGC_RSK_RSKp90_RPS6KA1_ST	P29317	EPHA2	Q15418	RPS6KA1	S636	S635F	635	Missense	proximal	-1	no	2.293	2.259	EPSD	COSMIC	1.787	Down-regulation
AGC_RSK_RSKp90_RPS6KA1_ST	P29317	EPHA2	Q15418	RPS6KA1	S749	R743G	743	Missense	distal	-6	no	1.039	1.947	EPSD	COSMIC	1.787	Gain
AGC_RSK_RSKp90_RPS6KA1_ST	P29317	EPHA2	Q15418	RPS6KA1	T773	G777S	777	Missense	distal	4	no	2.288	2.249	EPSD	COSMIC	1.787	Down-regulation
AGC_RSK_RSKp90_RPS6KA1_ST	P29317	EPHA2	Q15418	RPS6KA1	S790	K793R	793	Missense	distal	3	no	1.825	1.681	EPSD	COSMIC	1.787	Loss
AGC_RSK_RSKp90_RPS6KA1_ST	P29317	EPHA2	Q15418	RPS6KA1	S790	W783L	783	Missense	distal	-7	no	1.825	1.854	EPSD	COSMIC	1.787	Up-regulation
AGC_RSK_RSKp90_RPS6KA1_ST	P29317	EPHA2	Q15418	RPS6KA1	S790	R792Q	792	Missense	proximal	2	no	1.825	1.590	EPSD	COSMIC	1.787	Loss
AGC_RSK_RSKp90_RPS6KA1_ST	P29317	EPHA2	Q15418	RPS6KA1	S790	A785S	785	Missense	distal	-5	no	1.825	1.803	EPSD	COSMIC;CCLE	1.787	Down-regulation
AGC_RSK_RSKp90_RPS6KA1_ST	P29317	EPHA2	Q15418	RPS6KA1	S869	L871R	871	Missense	proximal	2	no	3.076	3.232	EPSD	COSMIC	1.787	Up-regulation
AGC_RSK_RSKp90_RPS6KA1_ST	P29317	EPHA2	Q15418	RPS6KA1	S869	R876H	876	Missense	distal	7	no	3.076	2.890	EPSD	COSMIC	1.787	Down-regulation
AGC_RSK_RSKp90_RPS6KA1_ST	P29317	EPHA2	Q15418	RPS6KA1	S869	D872Y	872	Missense	distal	3	no	3.076	3.046	EPSD	COSMIC	1.787	Down-regulation
AGC_RSK_RSKp90_RPS6KA1_ST	P29317	EPHA2	Q15418	RPS6KA1	S901	V904G	904	Missense	distal	3	no	1.961	1.968	EPSD	COSMIC	1.787	Up-regulation
AGC_RSK_RSKp90_RPS6KA1_ST	P29317	EPHA2	Q15418	RPS6KA1	S901	T908M	908	Missense	distal	7	no	1.961	2.004	EPSD	COSMIC	1.787	Up-regulation
AGC_RSK_RSKp90_RPS6KA1_ST	P29317	EPHA2	Q15418	RPS6KA1	S901	T898M	898	Missense	distal	-3	no	1.961	2.198	EPSD	COSMIC	1.787	Up-regulation
AGC_RSK_RSKp90_RPS6KA1_ST	P29317	EPHA2	Q15418	RPS6KA1	T922	A927V	927	Missense	distal	5	no	1.733	1.818	EPSD	COSMIC	1.787	Gain
AGC_RSK_RSKp90_RPS6KA1_ST	P23588	EIF4B	Q15418	RPS6KA1	S183	R190W	190	Missense	distal	7	no	2.232	2.238	EPSD	COSMIC	1.787	Up-regulation
AGC_RSK_RSKp90_RPS6KA1_ST	P23588	EIF4B	Q15418	RPS6KA1	S183	R186H	186	Missense	distal	3	no	2.232	2.345	EPSD	COSMIC	1.787	Up-regulation
AGC_RSK_RSKp90_RPS6KA1_ST	P23588	EIF4B	Q15418	RPS6KA1	S183	R190Q	190	Missense	distal	7	no	2.232	2.191	EPSD	COSMIC	1.787	Down-regulation
AGC_RSK_RSKp90_RPS6KA1_ST	P23588	EIF4B	Q15418	RPS6KA1	S183	R179M	179	Missense	distal	-4	no	2.232	2.201	EPSD	COSMIC	1.787	Down-regulation
AGC_RSK_RSKp90_RPS6KA1_ST	P23588	EIF4B	Q15418	RPS6KA1	T369	A371V	371	Missense	proximal	2	no	1.637	1.945	EPSD	COSMIC	1.787	Gain
AGC_RSK_RSKp90_RPS6KA1_ST	P23588	EIF4B	Q15418	RPS6KA1	T369	R372T	372	Missense	distal	3	no	1.637	1.802	EPSD	COSMIC	1.787	Gain
AGC_RSK_RSKp90_RPS6KA1_ST	P23588	EIF4B	Q15418	RPS6KA1	S424	S418T	418	Missense	distal	-6	no	1.301	1.998	EPSD	COSMIC	1.787	Gain
AGC_RSK_RSKp90_RPS6KA1_ST	P23588	EIF4B	Q15418	RPS6KA1	S434	E441K	441	Missense	distal	7	no	1.857	1.788	EPSD	COSMIC	1.787	Down-regulation
AGC_RSK_RSKp90_RPS6KA1_ST	P23588	EIF4B	Q15418	RPS6KA1	S434	G428E	428	Missense	distal	-6	no	1.857	1.369	EPSD	COSMIC;GDSC;CCLE	1.787	Loss
AGC_RSK_RSKp90_RPS6KA1_ST	P16144	ITGB4	Q15418	RPS6KA1	T168	T164N	164	Missense	distal	-4	no	1.859	1.680	EPSD	COSMIC	1.787	Loss
AGC_RSK_RSKp90_RPS6KA1_ST	P16144	ITGB4	Q15418	RPS6KA1	T1455	P1452T	1452	Missense	distal	-3	no	1.912	1.963	EPSD	COSMIC	1.787	Up-regulation
AGC_RSK_RSKp90_RPS6KA1_ST	P16144	ITGB4	Q15418	RPS6KA1	T1455	T1462N	1462	Missense	distal	7	no	1.912	2.044	EPSD	COSMIC	1.787	Up-regulation
AGC_RSK_RSKp90_RPS6KA1_ST	P16144	ITGB4	Q15418	RPS6KA1	T1455	S1457Y	1457	Missense	proximal	2	no	1.912	1.951	EPSD	COSMIC	1.787	Up-regulation
AGC_RSK_RSKp90_RPS6KA1_ST	P16144	ITGB4	Q15418	RPS6KA1	T1455	A1450V	1450	Missense	distal	-5	no	1.912	2.087	EPSD	COSMIC	1.787	Up-regulation
AGC_RSK_RSKp90_RPS6KA1_ST	P16144	ITGB4	Q15418	RPS6KA1	T1455	M1461V	1461	Missense	distal	6	no	1.912	1.797	EPSD	COSMIC	1.787	Down-regulation
AGC_RSK_RSKp90_RPS6KA1_ST	P16144	ITGB4	Q15418	RPS6KA1	T1455	P1452S	1452	Missense	distal	-3	no	1.912	2.010	EPSD	COSMIC	1.787	Up-regulation
AGC_RSK_RSKp90_RPS6KA1_ST	P16144	ITGB4	Q15418	RPS6KA1	S1501	E1499K	1499	Missense	proximal	-2	no	1.770	1.804	EPSD	COSMIC	1.787	Gain
AGC_RSK_RSKp90_RPS6KA1_ST	P16144	ITGB4	Q15418	RPS6KA1	S1501	R1497L	1497	Missense	distal	-4	no	1.770	1.892	EPSD	COSMIC	1.787	Gain
AGC_RSK_RSKp90_RPS6KA1_ST	P16144	ITGB4	Q15418	RPS6KA1	T1542	P1541S	1541	Missense	proximal	-1	no	3.274	3.291	EPSD	COSMIC	1.787	Up-regulation
AGC_RSK_RSKp90_RPS6KA1_ST	P16144	ITGB4	Q15418	RPS6KA1	T1542	S1543Y	1543	Missense	proximal	1	no	3.274	3.377	EPSD	COSMIC	1.787	Up-regulation
AGC_RSK_RSKp90_RPS6KA1_ST	Q9HC62	SENP2	Q15418	RPS6KA1	S38	S34C	34	Missense	distal	-4	no	1.771	1.844	EPSD	COSMIC	1.787	Gain
AGC_RSK_RSKp90_RPS6KA1_ST	Q9HC62	SENP2	Q15418	RPS6KA1	T39	S34C	34	Missense	distal	-5	no	2.466	2.729	EPSD	COSMIC	1.787	Up-regulation
AGC_RSK_RSKp90_RPS6KA1_ST	Q9HC62	SENP2	Q15418	RPS6KA1	S231	N238D	238	Missense	distal	7	no	2.091	2.078	EPSD	COSMIC	1.787	Down-regulation
AGC_RSK_RSKp90_RPS6KA1_ST	Q9HC62	SENP2	Q15418	RPS6KA1	S287	G280A	280	Missense	distal	-7	no	1.847	1.894	EPSD	COSMIC	1.787	Up-regulation
AGC_RSK_RSKp90_RPS6KA1_ST	Q9HC62	SENP2	Q15418	RPS6KA1	S287	R286I	286	Missense	proximal	-1	no	1.847	1.818	EPSD	COSMIC	1.787	Down-regulation
AGC_RSK_RSKp90_RPS6KA1_ST	Q9HC62	SENP2	Q15418	RPS6KA1	T369	D371A	371	Missense	proximal	2	no	2.495	2.286	PhosphoSitePlus	COSMIC	1.787	Down-regulation
AGC_RSK_RSKp90_RPS6KA1_ST	P01100	FOS	Q15418	RPS6KA1	S122	G127S	127	Missense	distal	5	no	1.778	2.009	EPSD	COSMIC	1.787	Gain
AGC_RSK_RSKp90_RPS6KA1_ST	P01100	FOS	Q15418	RPS6KA1	S281	A286T	286	Missense	distal	5	no	1.813	1.765	EPSD	COSMIC	1.787	Loss
AGC_RSK_RSKp90_RPS6KA1_ST	Q96RK0	CIC	Q15418	RPS6KA1	S119	V116L	116	Missense	distal	-3	no	1.200	1.855	EPSD	COSMIC	1.787	Gain
AGC_RSK_RSKp90_RPS6KA1_ST	Q96RK0	CIC	Q15418	RPS6KA1	S132	R139Q	139	Missense	distal	7	no	1.847	1.805	EPSD	COSMIC	1.787	Down-regulation
AGC_RSK_RSKp90_RPS6KA1_ST	Q96RK0	CIC	Q15418	RPS6KA1	S132	G133S	133	Missense	proximal	1	no	1.847	1.903	EPSD	COSMIC	1.787	Up-regulation
AGC_RSK_RSKp90_RPS6KA1_ST	Q96RK0	CIC	Q15418	RPS6KA1	S132	E137Q	137	Missense	distal	5	no	1.847	1.842	EPSD	COSMIC	1.787	Down-regulation
AGC_RSK_RSKp90_RPS6KA1_ST	Q96RK0	CIC	Q15418	RPS6KA1	S132	P135R	135	Missense	distal	3	no	1.847	1.738	EPSD	COSMIC	1.787	Loss
AGC_RSK_RSKp90_RPS6KA1_ST	Q96RK0	CIC	Q15418	RPS6KA1	S132	T127M	127	Missense	distal	-5	no	1.847	1.687	EPSD	COSMIC	1.787	Loss
AGC_RSK_RSKp90_RPS6KA1_ST	Q96RK0	CIC	Q15418	RPS6KA1	S132	P125S	125	Missense	distal	-7	no	1.847	1.855	EPSD	COSMIC	1.787	Up-regulation
AGC_RSK_RSKp90_RPS6KA1_ST	Q96RK0	CIC	Q15418	RPS6KA1	S154	M156I	156	Missense	proximal	2	no	1.711	1.857	EPSD	COSMIC	1.787	Gain
AGC_RSK_RSKp90_RPS6KA1_ST	Q96RK0	CIC	Q15418	RPS6KA1	S154	I160N	160	Missense	distal	6	no	1.711	1.826	EPSD	COSMIC	1.787	Gain
AGC_RSK_RSKp90_RPS6KA1_ST	Q96RK0	CIC	Q15418	RPS6KA1	S211	F207L	207	Missense	distal	-4	no	1.826	1.920	EPSD	COSMIC	1.787	Up-regulation
AGC_RSK_RSKp90_RPS6KA1_ST	Q96RK0	CIC	Q15418	RPS6KA1	S211	A216S	216	Missense	distal	5	no	1.826	1.778	EPSD	COSMIC	1.787	Loss
AGC_RSK_RSKp90_RPS6KA1_ST	Q96RK0	CIC	Q15418	RPS6KA1	S211	I209F	209	Missense	proximal	-2	no	1.826	1.833	EPSD	COSMIC	1.787	Up-regulation
AGC_RSK_RSKp90_RPS6KA1_ST	Q96RK0	CIC	Q15418	RPS6KA1	S211	I209S	209	Missense	proximal	-2	no	1.826	1.822	EPSD	COSMIC	1.787	Down-regulation
AGC_RSK_RSKp90_RPS6KA1_ST	Q96RK0	CIC	Q15418	RPS6KA1	S211	F207I	207	Missense	distal	-4	no	1.826	1.672	EPSD	COSMIC	1.787	Loss
AGC_RSK_RSKp90_RPS6KA1_ST	Q96RK0	CIC	Q15418	RPS6KA1	S211	N205I	205	Missense	distal	-6	no	1.826	1.982	EPSD	COSMIC	1.787	Up-regulation
AGC_RSK_RSKp90_RPS6KA1_ST	Q96RK0	CIC	Q15418	RPS6KA1	S211	N205H	205	Missense	distal	-6	no	1.826	2.283	EPSD	COSMIC	1.787	Up-regulation
AGC_RSK_RSKp90_RPS6KA1_ST	Q96RK0	CIC	Q15418	RPS6KA1	S211	R213W	213	Missense	proximal	2	no	1.826	1.766	EPSD	COSMIC	1.787	Loss
AGC_RSK_RSKp90_RPS6KA1_ST	Q96RK0	CIC	Q15418	RPS6KA1	S211	S211R	211	Missense	central	0	yes	1.826	0.000	EPSD	COSMIC	1.787	Loss
AGC_RSK_RSKp90_RPS6KA1_ST	Q96RK0	CIC	Q15418	RPS6KA1	S211	M204T	204	Missense	distal	-7	no	1.826	1.814	EPSD	COSMIC	1.787	Down-regulation
AGC_RSK_RSKp90_RPS6KA1_ST	Q96RK0	CIC	Q15418	RPS6KA1	S211	N205D	205	Missense	distal	-6	no	1.826	1.836	EPSD	COSMIC	1.787	Up-regulation
AGC_RSK_RSKp90_RPS6KA1_ST	Q96RK0	CIC	Q15418	RPS6KA1	T328	P331S	331	Missense	distal	3	no	1.900	1.836	EPSD	COSMIC	1.787	Down-regulation
AGC_RSK_RSKp90_RPS6KA1_ST	Q96RK0	CIC	Q15418	RPS6KA1	T328	L323F	323	Missense	distal	-5	no	1.900	1.888	EPSD	COSMIC	1.787	Down-regulation
AGC_RSK_RSKp90_RPS6KA1_ST	Q96RK0	CIC	Q15418	RPS6KA1	S333	P331S	331	Missense	proximal	-2	no	2.187	2.177	EPSD	COSMIC	1.787	Down-regulation
AGC_RSK_RSKp90_RPS6KA1_ST	Q96RK0	CIC	Q15418	RPS6KA1	S333	R340L	340	Missense	distal	7	no	2.187	2.087	EPSD	COSMIC;CCLE	1.787	Down-regulation
AGC_RSK_RSKp90_RPS6KA1_ST	Q96RK0	CIC	Q15418	RPS6KA1	S362	G359R	359	Missense	distal	-3	no	1.288	2.029	EPSD	COSMIC	1.787	Gain
AGC_RSK_RSKp90_RPS6KA1_ST	Q96RK0	CIC	Q15418	RPS6KA1	T421	R415W	415	Missense	distal	-6	no	1.933	2.266	EPSD	COSMIC	1.787	Up-regulation
AGC_RSK_RSKp90_RPS6KA1_ST	Q96RK0	CIC	Q15418	RPS6KA1	S479	D483N	483	Missense	distal	4	no	2.030	2.036	EPSD	COSMIC	1.787	Up-regulation
AGC_RSK_RSKp90_RPS6KA1_ST	Q96RK0	CIC	Q15418	RPS6KA1	S502	P509L	509	Missense	distal	7	no	1.897	1.802	EPSD	COSMIC	1.787	Down-regulation
AGC_RSK_RSKp90_RPS6KA1_ST	Q96RK0	CIC	Q15418	RPS6KA1	S502	P509S	509	Missense	distal	7	no	1.897	1.794	EPSD	COSMIC	1.787	Down-regulation
AGC_RSK_RSKp90_RPS6KA1_ST	Q96RK0	CIC	Q15418	RPS6KA1	S502	R507H	507	Missense	distal	5	no	1.897	1.549	EPSD	COSMIC;GDSC	1.787	Loss
AGC_RSK_RSKp90_RPS6KA1_ST	Q96RK0	CIC	Q15418	RPS6KA1	S502	S501Y	501	Missense	proximal	-1	no	1.897	1.857	EPSD	COSMIC	1.787	Down-regulation
AGC_RSK_RSKp90_RPS6KA1_ST	Q96RK0	CIC	Q15418	RPS6KA1	S502	P497S	497	Missense	distal	-5	no	1.897	1.762	EPSD	COSMIC	1.787	Loss
AGC_RSK_RSKp90_RPS6KA1_ST	Q96RK0	CIC	Q15418	RPS6KA1	S502	R500H	500	Missense	proximal	-2	no	1.897	1.984	EPSD	COSMIC;GDSC;CCLE	1.787	Up-regulation
AGC_RSK_RSKp90_RPS6KA1_ST	Q96RK0	CIC	Q15418	RPS6KA1	S502	P508H	508	Missense	distal	6	no	1.897	1.982	EPSD	COSMIC	1.787	Up-regulation
AGC_RSK_RSKp90_RPS6KA1_ST	Q96RK0	CIC	Q15418	RPS6KA1	T567	P573H	573	Missense	distal	6	no	1.902	1.988	EPSD	COSMIC	1.787	Up-regulation
AGC_RSK_RSKp90_RPS6KA1_ST	Q96RK0	CIC	Q15418	RPS6KA1	T567	E561D	561	Missense	distal	-6	no	1.902	1.837	EPSD	COSMIC	1.787	Down-regulation
AGC_RSK_RSKp90_RPS6KA1_ST	Q96RK0	CIC	Q15418	RPS6KA1	T567	Q560R	560	Missense	distal	-7	no	1.902	1.954	EPSD	COSMIC	1.787	Up-regulation
AGC_RSK_RSKp90_RPS6KA1_ST	Q96RK0	CIC	Q15418	RPS6KA1	S585	A578V	578	Missense	distal	-7	no	2.007	1.969	EPSD	COSMIC;GDSC;CCLE	1.787	Down-regulation
AGC_RSK_RSKp90_RPS6KA1_ST	Q96RK0	CIC	Q15418	RPS6KA1	S894	A900V	900	Missense	distal	6	no	2.127	2.053	EPSD	COSMIC	1.787	Down-regulation
AGC_RSK_RSKp90_RPS6KA1_ST	Q96RK0	CIC	Q15418	RPS6KA1	S894	P896L	896	Missense	proximal	2	no	2.127	1.943	EPSD	COSMIC	1.787	Down-regulation
AGC_RSK_RSKp90_RPS6KA1_ST	Q96RK0	CIC	Q15418	RPS6KA1	S894	P893S	893	Missense	proximal	-1	no	2.127	2.144	EPSD	COSMIC	1.787	Up-regulation
AGC_RSK_RSKp90_RPS6KA1_ST	Q96RK0	CIC	Q15418	RPS6KA1	S894	P897R	897	Missense	distal	3	no	2.127	2.018	EPSD	COSMIC	1.787	Down-regulation
AGC_RSK_RSKp90_RPS6KA1_ST	Q96RK0	CIC	Q15418	RPS6KA1	S894	S894C	894	Missense	central	0	yes	2.127	0.000	EPSD	COSMIC	1.787	Loss
AGC_RSK_RSKp90_RPS6KA1_ST	Q96RK0	CIC	Q15418	RPS6KA1	S1150	P1146L	1146	Missense	distal	-4	no	3.007	3.076	EPSD	COSMIC;GDSC	1.787	Up-regulation
AGC_RSK_RSKp90_RPS6KA1_ST	Q96RK0	CIC	Q15418	RPS6KA1	S1150	A1147V	1147	Missense	distal	-3	no	3.007	2.441	EPSD	COSMIC	1.787	Down-regulation
AGC_RSK_RSKp90_RPS6KA1_ST	Q96RK0	CIC	Q15418	RPS6KA1	S1150	P1148L	1148	Missense	proximal	-2	no	3.007	3.000	EPSD	COSMIC;GDSC;CCLE	1.787	Down-regulation
AGC_RSK_RSKp90_RPS6KA1_ST	Q96RK0	CIC	Q15418	RPS6KA1	S1150	A1155T	1155	Missense	distal	5	no	3.007	2.958	EPSD	COSMIC	1.787	Down-regulation
AGC_RSK_RSKp90_RPS6KA1_ST	Q96RK0	CIC	Q15418	RPS6KA1	S1163	M1160V	1160	Missense	distal	-3	no	2.471	2.113	EPSD	COSMIC	1.787	Down-regulation
AGC_RSK_RSKp90_RPS6KA1_ST	Q96RK0	CIC	Q15418	RPS6KA1	S1163	T1161S	1161	Missense	proximal	-2	no	2.471	2.430	EPSD	COSMIC	1.787	Down-regulation
AGC_RSK_RSKp90_RPS6KA1_ST	Q96RK0	CIC	Q15418	RPS6KA1	S1191	P1188A	1188	Missense	distal	-3	no	1.381	1.878	EPSD	COSMIC	1.787	Gain
AGC_RSK_RSKp90_RPS6KA1_ST	Q96RK0	CIC	Q15418	RPS6KA1	T1217	A1218V	1218	Missense	proximal	1	no	1.925	1.789	EPSD	COSMIC	1.787	Down-regulation
AGC_RSK_RSKp90_RPS6KA1_ST	Q96RK0	CIC	Q15418	RPS6KA1	T1217	E1215D	1215	Missense	proximal	-2	no	1.925	1.949	EPSD	COSMIC	1.787	Up-regulation
AGC_RSK_RSKp90_RPS6KA1_ST	Q96RK0	CIC	Q15418	RPS6KA1	T1217	P1210T	1210	Missense	distal	-7	no	1.925	1.923	EPSD	COSMIC	1.787	Down-regulation
AGC_RSK_RSKp90_RPS6KA1_ST	Q96RK0	CIC	Q15418	RPS6KA1	T1217	R1214Q	1214	Missense	distal	-3	no	1.925	1.515	EPSD	COSMIC	1.787	Loss
AGC_RSK_RSKp90_RPS6KA1_ST	Q96RK0	CIC	Q15418	RPS6KA1	T1217	E1222Q	1222	Missense	distal	5	no	1.925	1.921	EPSD	COSMIC	1.787	Down-regulation
AGC_RSK_RSKp90_RPS6KA1_ST	Q96RK0	CIC	Q15418	RPS6KA1	T1217	E1222G	1222	Missense	distal	5	no	1.925	1.683	EPSD	COSMIC	1.787	Loss
AGC_RSK_RSKp90_RPS6KA1_ST	Q96RK0	CIC	Q15418	RPS6KA1	S1246	P1248L	1248	Missense	proximal	2	no	2.501	2.318	EPSD	COSMIC	1.787	Down-regulation
AGC_RSK_RSKp90_RPS6KA1_ST	Q96RK0	CIC	Q15418	RPS6KA1	S1246	W1239R	1239	Missense	distal	-7	no	2.501	2.574	EPSD	COSMIC	1.787	Up-regulation
AGC_RSK_RSKp90_RPS6KA1_ST	Q96RK0	CIC	Q15418	RPS6KA1	S1246	P1248S	1248	Missense	proximal	2	no	2.501	2.323	EPSD	COSMIC	1.787	Down-regulation
AGC_RSK_RSKp90_RPS6KA1_ST	Q96RK0	CIC	Q15418	RPS6KA1	S1246	T1242R	1242	Missense	distal	-4	no	2.501	2.531	EPSD	COSMIC	1.787	Up-regulation
AGC_RSK_RSKp90_RPS6KA1_ST	Q96RK0	CIC	Q15418	RPS6KA1	S1246	T1240R	1240	Missense	distal	-6	no	2.501	1.564	EPSD	COSMIC	1.787	Loss
AGC_RSK_RSKp90_RPS6KA1_ST	P25963	NFKBIA	Q15418	RPS6KA1	S283	E284D	284	Missense	proximal	1	no	3.859	3.829	EPSD	COSMIC	1.787	Down-regulation
AGC_RSK_RSKp90_RPS6KA1_ST	P25963	NFKBIA	Q15418	RPS6KA1	S283	E287V	287	Missense	distal	4	no	3.859	3.804	EPSD	COSMIC	1.787	Down-regulation
AGC_RSK_RSKp90_RPS6KA1_ST	P25963	NFKBIA	Q15418	RPS6KA1	S283	Y289C	289	Missense	distal	6	no	3.859	3.766	EPSD	COSMIC	1.787	Down-regulation
AGC_RSK_RSKp90_RPS6KA1_ST	P25963	NFKBIA	Q15418	RPS6KA1	S283	N276K	276	Missense	distal	-7	no	3.859	3.858	EPSD	COSMIC	1.787	Down-regulation
TK_PDGFR_PDGFRA_Y	P16234	PDGFRA	P16234	PDGFRA	Y572	P577R	577	Missense	distal	5	no	13.678	13.384	EPSD;PhosphoSitePlus	COSMIC	8.840	Down-regulation
TK_PDGFR_PDGFRA_Y	P16234	PDGFRA	P16234	PDGFRA	Y572	P567T	567	Missense	distal	-5	no	13.678	13.941	EPSD;PhosphoSitePlus	COSMIC	8.840	Up-regulation
TK_PDGFR_PDGFRA_Y	P16234	PDGFRA	P16234	PDGFRA	Y572	H570R	570	Missense	proximal	-2	no	13.678	14.796	EPSD;PhosphoSitePlus	COSMIC	8.840	Up-regulation
TK_PDGFR_PDGFRA_Y	P16234	PDGFRA	P16234	PDGFRA	Y572	P577S	577	Missense	distal	5	no	13.678	12.918	EPSD;PhosphoSitePlus	COSMIC	8.840	Down-regulation
TK_PDGFR_PDGFRA_Y	P16234	PDGFRA	P16234	PDGFRA	Y572	P567S	567	Missense	distal	-5	no	13.678	13.141	EPSD;PhosphoSitePlus	COSMIC	8.840	Down-regulation
TK_PDGFR_PDGFRA_Y	P16234	PDGFRA	P16234	PDGFRA	Y572	D568Y	568	Missense	distal	-4	no	13.678	12.347	EPSD;PhosphoSitePlus	COSMIC	8.840	Down-regulation
TK_PDGFR_PDGFRA_Y	P16234	PDGFRA	P16234	PDGFRA	Y572	G569V	569	Missense	distal	-3	no	13.678	13.668	EPSD;PhosphoSitePlus	COSMIC	8.840	Down-regulation
TK_PDGFR_PDGFRA_Y	P16234	PDGFRA	P16234	PDGFRA	Y572	E571L	571	Missense	proximal	-1	no	13.678	13.553	EPSD;PhosphoSitePlus	COSMIC	8.840	Down-regulation
TK_PDGFR_PDGFRA_Y	P16234	PDGFRA	P16234	PDGFRA	Y572	I565V	565	Missense	distal	-7	no	13.678	12.831	EPSD;PhosphoSitePlus	COSMIC	8.840	Down-regulation
TK_PDGFR_PDGFRA_Y	P16234	PDGFRA	P16234	PDGFRA	Y574	P581S	581	Missense	distal	7	no	13.819	13.898	EPSD;PhosphoSitePlus	COSMIC	8.840	Up-regulation
TK_PDGFR_PDGFRA_Y	P16234	PDGFRA	P16234	PDGFRA	Y574	P577R	577	Missense	distal	3	no	13.819	13.130	EPSD;PhosphoSitePlus	COSMIC	8.840	Down-regulation
TK_PDGFR_PDGFRA_Y	P16234	PDGFRA	P16234	PDGFRA	Y574	P567T	567	Missense	distal	-7	no	13.819	13.491	EPSD;PhosphoSitePlus	COSMIC	8.840	Down-regulation
TK_PDGFR_PDGFRA_Y	P16234	PDGFRA	P16234	PDGFRA	Y574	H570R	570	Missense	distal	-4	no	13.819	14.017	EPSD;PhosphoSitePlus	COSMIC	8.840	Up-regulation
TK_PDGFR_PDGFRA_Y	P16234	PDGFRA	P16234	PDGFRA	Y574	L580M	580	Missense	distal	6	no	13.819	14.187	EPSD;PhosphoSitePlus	COSMIC	8.840	Up-regulation
TK_PDGFR_PDGFRA_Y	P16234	PDGFRA	P16234	PDGFRA	Y574	P577S	577	Missense	distal	3	no	13.819	12.302	EPSD;PhosphoSitePlus	COSMIC	8.840	Down-regulation
TK_PDGFR_PDGFRA_Y	P16234	PDGFRA	P16234	PDGFRA	Y574	P567S	567	Missense	distal	-7	no	13.819	14.446	EPSD;PhosphoSitePlus	COSMIC	8.840	Up-regulation
TK_PDGFR_PDGFRA_Y	P16234	PDGFRA	P16234	PDGFRA	Y574	D568Y	568	Missense	distal	-6	no	13.819	16.092	EPSD;PhosphoSitePlus	COSMIC	8.840	Up-regulation
TK_PDGFR_PDGFRA_Y	P16234	PDGFRA	P16234	PDGFRA	Y574	G569V	569	Missense	distal	-5	no	13.819	13.302	EPSD;PhosphoSitePlus	COSMIC	8.840	Down-regulation
TK_PDGFR_PDGFRA_Y	P16234	PDGFRA	P16234	PDGFRA	Y574	E571L	571	Missense	distal	-3	no	13.819	13.978	EPSD;PhosphoSitePlus	COSMIC	8.840	Up-regulation
TK_PDGFR_PDGFRA_Y	P16234	PDGFRA	P16234	PDGFRA	Y720	D714E	714	Missense	distal	-6	no	14.620	13.522	EPSD	COSMIC	8.840	Down-regulation
TK_PDGFR_PDGFRA_Y	P16234	PDGFRA	P16234	PDGFRA	Y720	F725L	725	Missense	distal	5	no	14.620	14.361	EPSD	COSMIC	8.840	Down-regulation
TK_PDGFR_PDGFRA_Y	P16234	PDGFRA	P16234	PDGFRA	Y720	I722N	722	Missense	proximal	2	no	14.620	15.276	EPSD	COSMIC	8.840	Up-regulation
TK_PDGFR_PDGFRA_Y	P16234	PDGFRA	P16234	PDGFRA	Y720	S724Y	724	Missense	distal	4	no	14.620	14.747	EPSD	COSMIC	8.840	Up-regulation
TK_PDGFR_PDGFRA_Y	P16234	PDGFRA	P16234	PDGFRA	Y731	F725L	725	Missense	distal	-6	no	14.394	13.670	EPSD	COSMIC	8.840	Down-regulation
TK_PDGFR_PDGFRA_Y	P16234	PDGFRA	P16234	PDGFRA	Y731	M732V	732	Missense	proximal	1	no	14.394	16.251	EPSD	COSMIC	8.840	Up-regulation
TK_PDGFR_PDGFRA_Y	P16234	PDGFRA	P16234	PDGFRA	Y731	Q736H	736	Missense	distal	5	no	14.394	14.596	EPSD	COSMIC;CCLE	8.840	Up-regulation
TK_PDGFR_PDGFRA_Y	P16234	PDGFRA	P16234	PDGFRA	Y731	M732I	732	Missense	proximal	1	no	14.394	16.053	EPSD	COSMIC	8.840	Up-regulation
TK_PDGFR_PDGFRA_Y	P16234	PDGFRA	P16234	PDGFRA	Y731	G729S	729	Missense	proximal	-2	no	14.394	16.074	EPSD	COSMIC	8.840	Up-regulation
TK_PDGFR_PDGFRA_Y	P16234	PDGFRA	P16234	PDGFRA	Y731	S724Y	724	Missense	distal	-7	no	14.394	12.779	EPSD	COSMIC	8.840	Down-regulation
TK_PDGFR_PDGFRA_Y	P16234	PDGFRA	P16234	PDGFRA	Y742	R748G	748	Missense	distal	6	no	23.643	24.445	EPSD	COSMIC	8.840	Up-regulation
TK_PDGFR_PDGFRA_Y	P16234	PDGFRA	P16234	PDGFRA	Y742	T739A	739	Missense	distal	-3	no	23.643	23.609	EPSD	COSMIC	8.840	Down-regulation
TK_PDGFR_PDGFRA_Y	P16234	PDGFRA	P16234	PDGFRA	Y742	E747Q	747	Missense	distal	5	no	23.643	25.323	EPSD	COSMIC	8.840	Up-regulation
TK_PDGFR_PDGFRA_Y	P16234	PDGFRA	P16234	PDGFRA	Y742	Q736H	736	Missense	distal	-6	no	23.643	23.622	EPSD	COSMIC;CCLE	8.840	Down-regulation
TK_PDGFR_PDGFRA_Y	P16234	PDGFRA	P16234	PDGFRA	Y742	P744S	744	Missense	proximal	2	no	23.643	23.855	EPSD	COSMIC	8.840	Up-regulation
TK_PDGFR_PDGFRA_Y	P16234	PDGFRA	P16234	PDGFRA	Y742	E747K	747	Missense	distal	5	no	23.643	23.785	EPSD	COSMIC	8.840	Up-regulation
TK_PDGFR_PDGFRA_Y	P16234	PDGFRA	P16234	PDGFRA	Y742	E747G	747	Missense	distal	5	no	23.643	26.056	EPSD	COSMIC	8.840	Up-regulation
TK_PDGFR_PDGFRA_Y	P16234	PDGFRA	P16234	PDGFRA	Y754	R748G	748	Missense	distal	-6	no	20.901	20.467	EPSD	COSMIC	8.840	Down-regulation
TK_PDGFR_PDGFRA_Y	P16234	PDGFRA	P16234	PDGFRA	Y754	E750D	750	Missense	distal	-4	no	20.901	20.261	EPSD	COSMIC	8.840	Down-regulation
TK_PDGFR_PDGFRA_Y	P16234	PDGFRA	P16234	PDGFRA	Y754	Q758R	758	Missense	distal	4	no	20.901	20.966	EPSD	COSMIC	8.840	Up-regulation
TK_PDGFR_PDGFRA_Y	P16234	PDGFRA	P16234	PDGFRA	Y754	E747Q	747	Missense	distal	-7	no	20.901	18.820	EPSD	COSMIC	8.840	Down-regulation
TK_PDGFR_PDGFRA_Y	P16234	PDGFRA	P16234	PDGFRA	Y754	E747K	747	Missense	distal	-7	no	20.901	21.011	EPSD	COSMIC	8.840	Up-regulation
TK_PDGFR_PDGFRA_Y	P16234	PDGFRA	P16234	PDGFRA	Y754	E747G	747	Missense	distal	-7	no	20.901	18.020	EPSD	COSMIC	8.840	Down-regulation
TK_PDGFR_PDGFRA_Y	P16234	PDGFRA	P16234	PDGFRA	Y762	Q758R	758	Missense	distal	-4	no	14.790	14.714	EPSD	COSMIC	8.840	Down-regulation
TK_PDGFR_PDGFRA_Y	P16234	PDGFRA	P16234	PDGFRA	Y762	D763Y	763	Missense	proximal	1	no	14.790	14.357	EPSD	COSMIC	8.840	Down-regulation
TK_PDGFR_PDGFRA_Y	P16234	PDGFRA	P16234	PDGFRA	Y762	R764C	764	Missense	proximal	2	no	14.790	15.627	EPSD	COSMIC	8.840	Up-regulation
TK_PDGFR_PDGFRA_Y	P16234	PDGFRA	P16234	PDGFRA	Y768	D763Y	763	Missense	distal	-5	no	14.461	16.063	EPSD	COSMIC	8.840	Up-regulation
TK_PDGFR_PDGFRA_Y	P16234	PDGFRA	P16234	PDGFRA	Y768	R764C	764	Missense	distal	-4	no	14.461	14.185	EPSD	COSMIC	8.840	Down-regulation
TK_PDGFR_PDGFRA_Y	P16234	PDGFRA	P16234	PDGFRA	Y768	D775H	775	Missense	distal	7	no	14.461	14.210	EPSD	COSMIC	8.840	Down-regulation
TK_PDGFR_PDGFRA_Y	P16234	PDGFRA	P16234	PDGFRA	Y768	K771T	771	Missense	distal	3	no	14.461	13.288	EPSD	COSMIC	8.840	Down-regulation
TK_PDGFR_PDGFRA_Y	P16234	PDGFRA	P16234	PDGFRA	Y849	D842V	842	Missense	distal	-7	no	9.824	11.258	EPSD	COSMIC	8.840	Up-regulation
TK_PDGFR_PDGFRA_Y	P16234	PDGFRA	P16234	PDGFRA	Y849	Y849D	849	Missense	central	0	yes	9.824	0.000	EPSD	COSMIC	8.840	Loss
TK_PDGFR_PDGFRA_Y	P16234	PDGFRA	P16234	PDGFRA	Y849	D846Y	846	Missense	distal	-3	no	9.824	10.119	EPSD	COSMIC	8.840	Up-regulation
TK_PDGFR_PDGFRA_Y	P16234	PDGFRA	P16234	PDGFRA	Y849	H845Y	845	Missense	distal	-4	no	9.824	9.062	EPSD	COSMIC	8.840	Down-regulation
TK_PDGFR_PDGFRA_Y	P16234	PDGFRA	P16234	PDGFRA	Y849	D842I	842	Missense	distal	-7	no	9.824	12.104	EPSD	COSMIC	8.840	Up-regulation
TK_PDGFR_PDGFRA_Y	P16234	PDGFRA	P16234	PDGFRA	Y849	Y849H	849	Missense	central	0	yes	9.824	0.000	EPSD	COSMIC	8.840	Loss
TK_PDGFR_PDGFRA_Y	P16234	PDGFRA	P16234	PDGFRA	Y849	Y849C	849	Missense	central	0	yes	9.824	0.000	EPSD	COSMIC	8.840	Loss
TK_PDGFR_PDGFRA_Y	P16234	PDGFRA	P16234	PDGFRA	Y849	D846E	846	Missense	distal	-3	no	9.824	9.904	EPSD	COSMIC	8.840	Up-regulation
TK_PDGFR_PDGFRA_Y	P16234	PDGFRA	P16234	PDGFRA	Y849	D842E	842	Missense	distal	-7	no	9.824	12.832	EPSD	COSMIC	8.840	Up-regulation
TK_PDGFR_PDGFRA_Y	P16234	PDGFRA	P16234	PDGFRA	Y849	S851W	851	Missense	proximal	2	no	9.824	10.035	EPSD	COSMIC	8.840	Up-regulation
TK_PDGFR_PDGFRA_Y	P16234	PDGFRA	P16234	PDGFRA	Y849	D842H	842	Missense	distal	-7	no	9.824	11.315	EPSD	COSMIC	8.840	Up-regulation
TK_PDGFR_PDGFRA_Y	P16234	PDGFRA	P16234	PDGFRA	Y849	D846V	846	Missense	distal	-3	no	9.824	9.983	EPSD	COSMIC	8.840	Up-regulation
TK_PDGFR_PDGFRA_Y	P16234	PDGFRA	P16234	PDGFRA	Y849	D846A	846	Missense	distal	-3	no	9.824	9.951	EPSD	COSMIC	8.840	Up-regulation
TK_PDGFR_PDGFRA_Y	P16234	PDGFRA	P16234	PDGFRA	Y849	D846G	846	Missense	distal	-3	no	9.824	9.992	EPSD	COSMIC	8.840	Up-regulation
TK_PDGFR_PDGFRA_Y	P16234	PDGFRA	P16234	PDGFRA	Y849	S851P	851	Missense	proximal	2	no	9.824	9.612	EPSD	COSMIC	8.840	Down-regulation
TK_PDGFR_PDGFRA_Y	P16234	PDGFRA	P16234	PDGFRA	Y849	D842A	842	Missense	distal	-7	no	9.824	12.546	EPSD	COSMIC	8.840	Up-regulation
TK_PDGFR_PDGFRA_Y	P16234	PDGFRA	P16234	PDGFRA	Y849	M844V	844	Missense	distal	-5	no	9.824	9.826	EPSD	COSMIC	8.840	Up-regulation
TK_PDGFR_PDGFRA_Y	P16234	PDGFRA	P16234	PDGFRA	Y849	H845D	845	Missense	distal	-4	no	9.824	10.393	EPSD	COSMIC	8.840	Up-regulation
TK_PDGFR_PDGFRA_Y	P16234	PDGFRA	P16234	PDGFRA	Y849	D842F	842	Missense	distal	-7	no	9.824	10.788	EPSD	COSMIC	8.840	Up-regulation
TK_PDGFR_PDGFRA_Y	P16234	PDGFRA	P16234	PDGFRA	Y849	I843V	843	Missense	distal	-6	no	9.824	9.630	EPSD	COSMIC	8.840	Down-regulation
TK_PDGFR_PDGFRA_Y	P16234	PDGFRA	P16234	PDGFRA	Y988	R981L	981	Missense	distal	-7	no	24.666	23.572	EPSD;PhosphoSitePlus	COSMIC	8.840	Down-regulation
TK_PDGFR_PDGFRA_Y	P16234	PDGFRA	P16234	PDGFRA	Y988	G990R	990	Missense	proximal	2	no	24.666	24.687	EPSD;PhosphoSitePlus	COSMIC	8.840	Up-regulation
TK_PDGFR_PDGFRA_Y	P16234	PDGFRA	P16234	PDGFRA	Y988	I989T	989	Missense	proximal	1	no	24.666	21.488	EPSD;PhosphoSitePlus	COSMIC	8.840	Down-regulation
TK_PDGFR_PDGFRA_Y	P16234	PDGFRA	P16234	PDGFRA	Y988	A987V	987	Missense	proximal	-1	no	24.666	24.610	EPSD;PhosphoSitePlus	COSMIC	8.840	Down-regulation
TK_PDGFR_PDGFRA_Y	P16234	PDGFRA	P16234	PDGFRA	Y988	I989V	989	Missense	proximal	1	no	24.666	24.863	EPSD;PhosphoSitePlus	COSMIC	8.840	Up-regulation
TK_PDGFR_PDGFRA_Y	P16234	PDGFRA	P16234	PDGFRA	Y988	D983N	983	Missense	distal	-5	no	24.666	25.537	EPSD;PhosphoSitePlus	COSMIC	8.840	Up-regulation
TK_PDGFR_PDGFRA_Y	P16234	PDGFRA	P16234	PDGFRA	Y1018	I1019T	1019	Missense	proximal	1	no	20.400	17.222	PhosphoSitePlus;EPSD	COSMIC	8.840	Down-regulation
TK_PDGFR_PDGFRA_Y	P16234	PDGFRA	P16234	PDGFRA	Y1018	S1013I	1013	Missense	distal	-5	no	20.400	19.756	PhosphoSitePlus;EPSD	COSMIC	8.840	Down-regulation
TK_PDGFR_PDGFRA_Y	P16234	PDGFRA	P16234	PDGFRA	Y1018	I1020V	1020	Missense	proximal	2	no	20.400	21.570	PhosphoSitePlus;EPSD	COSMIC	8.840	Up-regulation
TK_PDGFR_PDGFRA_Y	P16234	PDGFRA	P16234	PDGFRA	Y1018	G1017V	1017	Missense	proximal	-1	no	20.400	20.428	PhosphoSitePlus;EPSD	COSMIC;GDSC;CCLE	8.840	Up-regulation
TK_PDGFR_PDGFRA_Y	P16234	PDGFRA	P16234	PDGFRA	Y1018	D1015H	1015	Missense	distal	-3	no	20.400	20.506	PhosphoSitePlus;EPSD	COSMIC	8.840	Up-regulation
TK_PDGFR_PDGFRA_Y	P16234	PDGFRA	P16234	PDGFRA	Y1018	D1024N	1024	Missense	distal	6	no	20.400	19.243	PhosphoSitePlus;EPSD	COSMIC	8.840	Down-regulation
TK_PDGFR_PDGFRA_Y	P16234	PDGFRA	P16234	PDGFRA	Y1018	G1017D	1017	Missense	proximal	-1	no	20.400	20.471	PhosphoSitePlus;EPSD	COSMIC	8.840	Up-regulation
TK_PDGFR_PDGFRA_Y	Q9P219	CCDC88C	P16234	PDGFRA	Y2025	T2020I	2020	Missense	distal	-5	no	9.166	7.722	PhosphoSitePlus	COSMIC	8.840	Loss
TK_PDGFR_PDGFRA_Y	P12931	SRC	P16234	PDGFRA	Y419	A421V	421	Missense	proximal	2	no	18.156	18.416	PhosphoSitePlus	COSMIC	8.840	Up-regulation
TK_PDGFR_PDGFRA_Y	P12931	SRC	P16234	PDGFRA	Y419	Y419H	419	Missense	central	0	yes	18.156	0.000	PhosphoSitePlus	COSMIC	8.840	Loss
AGC_GRK_BARK_GRK2_ST	P25101	EDNRA	P25098	GRK2	T403	T403K	403	Missense	central	0	yes	135.683	0.000	EPSD;PhosphoSitePlus	COSMIC	128.034	Loss
AGC_GRK_BARK_GRK2_ST	P25101	EDNRA	P25098	GRK2	T403	K408N	408	Missense	distal	5	no	135.683	133.626	EPSD;PhosphoSitePlus	COSMIC	128.034	Down-regulation
AGC_GRK_BARK_GRK2_ST	P25101	EDNRA	P25098	GRK2	S404	T403K	403	Missense	proximal	-1	no	127.709	129.177	EPSD;PhosphoSitePlus	COSMIC	128.034	Gain
AGC_GRK_BARK_GRK2_ST	P25101	EDNRA	P25098	GRK2	S404	K408N	408	Missense	distal	4	no	127.709	130.336	EPSD;PhosphoSitePlus	COSMIC	128.034	Gain
AGC_GRK_BARK_GRK2_ST	P25101	EDNRA	P25098	GRK2	T417	K423N	423	Missense	distal	6	no	147.721	151.792	EPSD	COSMIC	128.034	Up-regulation
AGC_GRK_BARK_GRK2_ST	P25101	EDNRA	P25098	GRK2	T417	T417P	417	Missense	central	0	yes	147.721	0.000	EPSD	COSMIC	128.034	Loss
AGC_GRK_BARK_GRK2_ST	P25101	EDNRA	P25098	GRK2	S420	K423N	423	Missense	distal	3	no	172.684	172.728	EPSD	COSMIC	128.034	Up-regulation
AGC_GRK_BARK_GRK2_ST	P25101	EDNRA	P25098	GRK2	S420	T417P	417	Missense	distal	-3	no	172.684	153.393	EPSD	COSMIC	128.034	Down-regulation
AGC_GRK_BARK_GRK2_ST	P25101	EDNRA	P25098	GRK2	S421	K423N	423	Missense	proximal	2	no	163.010	163.416	EPSD	COSMIC	128.034	Up-regulation
AGC_GRK_BARK_GRK2_ST	P25101	EDNRA	P25098	GRK2	S421	T417P	417	Missense	distal	-4	no	163.010	153.819	EPSD	COSMIC	128.034	Down-regulation
AGC_GRK_BARK_GRK2_ST	P25101	EDNRA	P25098	GRK2	S425	K423N	423	Missense	proximal	-2	no	151.589	155.212	EPSD	COSMIC	128.034	Up-regulation
AGC_GRK_BARK_GRK2_ST	P35241	RDX	P25098	GRK2	T518	R514C	514	Missense	distal	-4	no	130.436	134.679	EPSD	COSMIC;GDSC;CCLE	128.034	Up-regulation
AGC_GRK_BARK_GRK2_ST	P35241	RDX	P25098	GRK2	T518	T516I	516	Missense	proximal	-2	no	130.436	118.911	EPSD	COSMIC	128.034	Loss
AGC_GRK_BARK_GRK2_ST	P35241	RDX	P25098	GRK2	T518	E522K	522	Missense	distal	4	no	130.436	125.330	EPSD	COSMIC	128.034	Loss
AGC_GRK_BARK_GRK2_ST	P35241	RDX	P25098	GRK2	T518	E511K	511	Missense	distal	-7	no	130.436	130.825	EPSD	COSMIC	128.034	Up-regulation
AGC_GRK_BARK_GRK2_ST	P35241	RDX	P25098	GRK2	T518	E517K	517	Missense	proximal	-1	no	130.436	119.008	EPSD	COSMIC;GDSC;CCLE	128.034	Loss
AGC_GRK_BARK_GRK2_ST	P35241	RDX	P25098	GRK2	T545	A552T	552	Missense	distal	7	no	129.999	129.948	EPSD	COSMIC	128.034	Down-regulation
AGC_GRK_BARK_GRK2_ST	P35241	RDX	P25098	GRK2	T564	G571C	571	Missense	distal	7	no	167.189	166.971	PhosphoSitePlus	COSMIC	128.034	Down-regulation
AGC_GRK_BARK_GRK2_ST	P35241	RDX	P25098	GRK2	T564	R559C	559	Missense	distal	-5	no	167.189	159.769	PhosphoSitePlus	COSMIC	128.034	Down-regulation
AGC_GRK_BARK_GRK2_ST	P41143	OPRD1	P25098	GRK2	S344	S344R	344	Missense	central	0	yes	141.487	0.000	EPSD	COSMIC	128.034	Loss
AGC_GRK_BARK_GRK2_ST	P41143	OPRD1	P25098	GRK2	S344	A351V	351	Missense	distal	7	no	141.487	141.668	EPSD	COSMIC;CCLE	128.034	Up-regulation
AGC_GRK_BARK_GRK2_ST	P41143	OPRD1	P25098	GRK2	T358	R356G	356	Missense	proximal	-2	no	155.406	148.243	EPSD	COSMIC	128.034	Down-regulation
AGC_GRK_BARK_GRK2_ST	P41143	OPRD1	P25098	GRK2	T358	A351V	351	Missense	distal	-7	no	155.406	153.168	EPSD	COSMIC;CCLE	128.034	Down-regulation
AGC_GRK_BARK_GRK2_ST	P41143	OPRD1	P25098	GRK2	T358	G365D	365	Missense	distal	7	no	155.406	154.992	EPSD	COSMIC	128.034	Down-regulation
AGC_GRK_BARK_GRK2_ST	P41143	OPRD1	P25098	GRK2	T361	R356G	356	Missense	distal	-5	no	152.449	149.894	EPSD	COSMIC	128.034	Down-regulation
AGC_GRK_BARK_GRK2_ST	P41143	OPRD1	P25098	GRK2	T361	G367D	367	Missense	distal	6	no	152.449	151.902	EPSD	COSMIC;CCLE	128.034	Down-regulation
AGC_GRK_BARK_GRK2_ST	P41143	OPRD1	P25098	GRK2	T361	G365D	365	Missense	distal	4	no	152.449	154.622	EPSD	COSMIC	128.034	Up-regulation
AGC_GRK_BARK_GRK2_ST	P41143	OPRD1	P25098	GRK2	S363	R356G	356	Missense	distal	-7	no	149.684	148.883	PhosphoSitePlus	COSMIC	128.034	Down-regulation
AGC_GRK_BARK_GRK2_ST	P41143	OPRD1	P25098	GRK2	S363	G367D	367	Missense	distal	4	no	149.684	151.858	PhosphoSitePlus	COSMIC;CCLE	128.034	Up-regulation
AGC_GRK_BARK_GRK2_ST	P41143	OPRD1	P25098	GRK2	S363	G365D	365	Missense	proximal	2	no	149.684	149.814	PhosphoSitePlus	COSMIC	128.034	Up-regulation
AGC_GRK_BARK_GRK2_ST	P15311	EZR	P25098	GRK2	T332	V333M	333	Missense	proximal	1	no	146.185	147.779	EPSD	COSMIC;CCLE	128.034	Up-regulation
AGC_GRK_BARK_GRK2_ST	P15311	EZR	P25098	GRK2	T332	V333L	333	Missense	proximal	1	no	146.185	146.566	EPSD	COSMIC	128.034	Up-regulation
AGC_GRK_BARK_GRK2_ST	P15311	EZR	P25098	GRK2	T332	E338G	338	Missense	distal	6	no	146.185	144.596	EPSD	COSMIC	128.034	Down-regulation
AGC_GRK_BARK_GRK2_ST	P15311	EZR	P25098	GRK2	T548	H554R	554	Missense	distal	6	no	143.837	146.921	EPSD	COSMIC	128.034	Up-regulation
AGC_GRK_BARK_GRK2_ST	P15311	EZR	P25098	GRK2	T576	K577N	577	Missense	proximal	1	no	131.411	145.673	EPSD	COSMIC	128.034	Up-regulation
AGC_GRK_BARK_GRK2_ST	P07550	ADRB2	P25098	GRK2	S355	S355F	355	Missense	central	0	yes	139.357	0.000	EPSD;PhosphoSitePlus	COSMIC	128.034	Loss
AGC_GRK_BARK_GRK2_ST	P07550	ADRB2	P25098	GRK2	S356	S355F	355	Missense	proximal	-1	no	164.244	154.231	EPSD;PhosphoSitePlus	COSMIC	128.034	Down-regulation
AGC_GRK_BARK_GRK2_ST	P07550	ADRB2	P25098	GRK2	T384	D380H	380	Missense	distal	-4	no	151.353	126.181	EPSD;PhosphoSitePlus	COSMIC;GDSC;CCLE	128.034	Loss
AGC_GRK_BARK_GRK2_ST	P07550	ADRB2	P25098	GRK2	T384	E385V	385	Missense	proximal	1	no	151.353	141.764	EPSD;PhosphoSitePlus	COSMIC	128.034	Down-regulation
AGC_GRK_BARK_GRK2_ST	P07550	ADRB2	P25098	GRK2	T393	N398S	398	Missense	distal	5	no	129.526	134.474	EPSD	COSMIC	128.034	Up-regulation
AGC_GRK_BARK_GRK2_ST	P07550	ADRB2	P25098	GRK2	T393	S396G	396	Missense	distal	3	no	129.526	132.008	EPSD	COSMIC	128.034	Up-regulation
AGC_GRK_BARK_GRK2_ST	P07550	ADRB2	P25098	GRK2	S396	N398S	398	Missense	proximal	2	no	164.934	164.264	PhosphoSitePlus;EPSD	COSMIC	128.034	Down-regulation
AGC_GRK_BARK_GRK2_ST	P07550	ADRB2	P25098	GRK2	S396	S396G	396	Missense	central	0	yes	164.934	0.000	PhosphoSitePlus;EPSD	COSMIC	128.034	Loss
AGC_GRK_BARK_GRK2_ST	P07550	ADRB2	P25098	GRK2	S401	R404W	404	Missense	distal	3	no	165.208	158.529	EPSD;PhosphoSitePlus	COSMIC;CCLE	128.034	Down-regulation
AGC_GRK_BARK_GRK2_ST	P07550	ADRB2	P25098	GRK2	S401	N398S	398	Missense	distal	-3	no	165.208	154.860	EPSD;PhosphoSitePlus	COSMIC	128.034	Down-regulation
AGC_GRK_BARK_GRK2_ST	P07550	ADRB2	P25098	GRK2	S401	S407N	407	Missense	distal	6	no	165.208	167.819	EPSD;PhosphoSitePlus	COSMIC	128.034	Up-regulation
AGC_GRK_BARK_GRK2_ST	P07550	ADRB2	P25098	GRK2	S401	S396G	396	Missense	distal	-5	no	165.208	167.421	EPSD;PhosphoSitePlus	COSMIC	128.034	Up-regulation
AGC_GRK_BARK_GRK2_ST	P07550	ADRB2	P25098	GRK2	S407	R404W	404	Missense	distal	-3	no	147.963	155.386	EPSD;PhosphoSitePlus	COSMIC;CCLE	128.034	Up-regulation
AGC_GRK_BARK_GRK2_ST	P07550	ADRB2	P25098	GRK2	S407	N409S	409	Missense	proximal	2	no	147.963	147.292	EPSD;PhosphoSitePlus	COSMIC	128.034	Down-regulation
AGC_GRK_BARK_GRK2_ST	P07550	ADRB2	P25098	GRK2	S407	S407N	407	Missense	central	0	yes	147.963	0.000	EPSD;PhosphoSitePlus	COSMIC	128.034	Loss
AGC_GRK_BARK_GRK2_ST	P07550	ADRB2	P25098	GRK2	T408	R404W	404	Missense	distal	-4	no	132.393	132.532	EPSD	COSMIC;CCLE	128.034	Up-regulation
AGC_GRK_BARK_GRK2_ST	P07550	ADRB2	P25098	GRK2	T408	N409S	409	Missense	proximal	1	no	132.393	131.535	EPSD	COSMIC	128.034	Down-regulation
AGC_GRK_BARK_GRK2_ST	P07550	ADRB2	P25098	GRK2	T408	S407N	407	Missense	proximal	-1	no	132.393	132.595	EPSD	COSMIC	128.034	Up-regulation
AGC_GRK_BARK_GRK2_ST	P07550	ADRB2	P25098	GRK2	S411	R404W	404	Missense	distal	-7	no	154.701	149.721	EPSD;PhosphoSitePlus	COSMIC;CCLE	128.034	Down-regulation
AGC_GRK_BARK_GRK2_ST	P07550	ADRB2	P25098	GRK2	S411	N409S	409	Missense	proximal	-2	no	154.701	155.882	EPSD;PhosphoSitePlus	COSMIC	128.034	Up-regulation
AGC_GRK_BARK_GRK2_ST	P07550	ADRB2	P25098	GRK2	S411	S407N	407	Missense	distal	-4	no	154.701	151.226	EPSD;PhosphoSitePlus	COSMIC	128.034	Down-regulation
AGC_GRK_BARK_GRK2_ST	Q14940	SLC9A5	P25098	GRK2	S702	E705D	705	Missense	distal	3	no	134.734	130.313	EPSD;PhosphoSitePlus	COSMIC;GDSC;CCLE	128.034	Down-regulation
AGC_GRK_BARK_GRK2_ST	Q14940	SLC9A5	P25098	GRK2	S709	E713Q	713	Missense	distal	4	no	157.087	158.842	EPSD;PhosphoSitePlus	COSMIC	128.034	Up-regulation
AGC_GRK_BARK_GRK2_ST	Q14940	SLC9A5	P25098	GRK2	S709	E705D	705	Missense	distal	-4	no	157.087	166.828	EPSD;PhosphoSitePlus	COSMIC;GDSC;CCLE	128.034	Up-regulation
AGC_GRK_BARK_GRK2_ST	Q14940	SLC9A5	P25098	GRK2	S711	E713Q	713	Missense	proximal	2	no	155.358	153.103	EPSD;PhosphoSitePlus	COSMIC	128.034	Down-regulation
AGC_GRK_BARK_GRK2_ST	Q14940	SLC9A5	P25098	GRK2	S711	E705D	705	Missense	distal	-6	no	155.358	157.189	EPSD;PhosphoSitePlus	COSMIC;GDSC;CCLE	128.034	Up-regulation
AGC_GRK_BARK_GRK2_ST	Q14940	SLC9A5	P25098	GRK2	S712	E713Q	713	Missense	proximal	1	no	154.074	148.094	PhosphoSitePlus;EPSD	COSMIC	128.034	Down-regulation
AGC_GRK_BARK_GRK2_ST	Q14940	SLC9A5	P25098	GRK2	S712	E705D	705	Missense	distal	-7	no	154.074	152.379	PhosphoSitePlus;EPSD	COSMIC;GDSC;CCLE	128.034	Down-regulation
AGC_GRK_BARK_GRK2_ST	Q14940	SLC9A5	P25098	GRK2	T714	E713Q	713	Missense	proximal	-1	no	178.110	174.988	EPSD;PhosphoSitePlus	COSMIC	128.034	Down-regulation
AGC_GRK_BARK_GRK2_ST	P08172	CHRM2	P25098	GRK2	S232	A226T	226	Missense	distal	-6	no	135.315	136.320	EPSD;PhosphoSitePlus	COSMIC	128.034	Up-regulation
AGC_GRK_BARK_GRK2_ST	P08172	CHRM2	P25098	GRK2	S232	P233S	233	Missense	proximal	1	no	135.315	142.476	EPSD;PhosphoSitePlus	COSMIC	128.034	Up-regulation
AGC_GRK_BARK_GRK2_ST	P08172	CHRM2	P25098	GRK2	S232	S234R	234	Missense	proximal	2	no	135.315	138.181	EPSD;PhosphoSitePlus	COSMIC	128.034	Up-regulation
AGC_GRK_BARK_GRK2_ST	P08172	CHRM2	P25098	GRK2	S232	N227I	227	Missense	distal	-5	no	135.315	126.509	EPSD;PhosphoSitePlus	COSMIC	128.034	Loss
AGC_GRK_BARK_GRK2_ST	P08172	CHRM2	P25098	GRK2	S234	P233S	233	Missense	proximal	-1	no	135.010	131.073	EPSD;PhosphoSitePlus	COSMIC	128.034	Down-regulation
AGC_GRK_BARK_GRK2_ST	P08172	CHRM2	P25098	GRK2	S234	S234R	234	Missense	central	0	yes	135.010	0.000	EPSD;PhosphoSitePlus	COSMIC	128.034	Loss
AGC_GRK_BARK_GRK2_ST	P08172	CHRM2	P25098	GRK2	S234	N227I	227	Missense	distal	-7	no	135.010	135.079	EPSD;PhosphoSitePlus	COSMIC	128.034	Up-regulation
AGC_GRK_BARK_GRK2_ST	P08172	CHRM2	P25098	GRK2	S250	N247S	247	Missense	distal	-3	no	154.968	144.620	EPSD;PhosphoSitePlus	COSMIC	128.034	Down-regulation
AGC_GRK_BARK_GRK2_ST	P08172	CHRM2	P25098	GRK2	S250	N244K	244	Missense	distal	-6	no	154.968	149.756	EPSD;PhosphoSitePlus	COSMIC	128.034	Down-regulation
AGC_GRK_BARK_GRK2_ST	P08172	CHRM2	P25098	GRK2	S251	N247S	247	Missense	distal	-4	no	143.627	147.102	EPSD;PhosphoSitePlus	COSMIC	128.034	Up-regulation
AGC_GRK_BARK_GRK2_ST	P08172	CHRM2	P25098	GRK2	S251	N244K	244	Missense	distal	-7	no	143.627	144.453	EPSD;PhosphoSitePlus	COSMIC	128.034	Up-regulation
AGC_GRK_BARK_GRK2_ST	P08172	CHRM2	P25098	GRK2	S251	N258S	258	Missense	distal	7	no	143.627	143.247	EPSD;PhosphoSitePlus	COSMIC	128.034	Down-regulation
AGC_GRK_BARK_GRK2_ST	P08172	CHRM2	P25098	GRK2	T271	C274Y	274	Missense	distal	3	no	142.748	139.115	EPSD;PhosphoSitePlus	COSMIC	128.034	Down-regulation
AGC_GRK_BARK_GRK2_ST	P08172	CHRM2	P25098	GRK2	T271	D268N	268	Missense	distal	-3	no	142.748	139.470	EPSD;PhosphoSitePlus	COSMIC	128.034	Down-regulation
AGC_GRK_BARK_GRK2_ST	P08172	CHRM2	P25098	GRK2	S282	K280R	280	Missense	proximal	-2	no	152.972	151.471	EPSD;PhosphoSitePlus	COSMIC	128.034	Down-regulation
AGC_GRK_BARK_GRK2_ST	P08172	CHRM2	P25098	GRK2	S282	N284H	284	Missense	proximal	2	no	152.972	149.564	EPSD;PhosphoSitePlus	COSMIC	128.034	Down-regulation
AGC_GRK_BARK_GRK2_ST	P08172	CHRM2	P25098	GRK2	S283	K280R	280	Missense	distal	-3	no	138.399	148.744	EPSD;PhosphoSitePlus	COSMIC	128.034	Up-regulation
AGC_GRK_BARK_GRK2_ST	P08172	CHRM2	P25098	GRK2	S283	N284H	284	Missense	proximal	1	no	138.399	140.688	EPSD;PhosphoSitePlus	COSMIC	128.034	Up-regulation
AGC_GRK_BARK_GRK2_ST	P08172	CHRM2	P25098	GRK2	S286	K280R	280	Missense	distal	-6	no	149.588	150.574	EPSD;PhosphoSitePlus	COSMIC	128.034	Up-regulation
AGC_GRK_BARK_GRK2_ST	P08172	CHRM2	P25098	GRK2	S286	N284H	284	Missense	proximal	-2	no	149.588	142.971	EPSD;PhosphoSitePlus	COSMIC	128.034	Down-regulation
AGC_GRK_BARK_GRK2_ST	P08172	CHRM2	P25098	GRK2	T287	K280R	280	Missense	distal	-7	no	162.650	161.019	EPSD;PhosphoSitePlus	COSMIC	128.034	Down-regulation
AGC_GRK_BARK_GRK2_ST	P08172	CHRM2	P25098	GRK2	T287	N284H	284	Missense	distal	-3	no	162.650	153.444	EPSD;PhosphoSitePlus	COSMIC	128.034	Down-regulation
AGC_GRK_BARK_GRK2_ST	P08172	CHRM2	P25098	GRK2	S288	N284H	284	Missense	distal	-4	no	156.673	143.356	EPSD;PhosphoSitePlus	COSMIC	128.034	Down-regulation
AGC_GRK_BARK_GRK2_ST	P08172	CHRM2	P25098	GRK2	S290	N284H	284	Missense	distal	-6	no	145.638	139.434	EPSD;PhosphoSitePlus	COSMIC	128.034	Down-regulation
AGC_GRK_BARK_GRK2_ST	P08172	CHRM2	P25098	GRK2	S294	D299N	299	Missense	distal	5	no	138.400	132.503	EPSD;PhosphoSitePlus	COSMIC	128.034	Down-regulation
AGC_GRK_BARK_GRK2_ST	P08172	CHRM2	P25098	GRK2	S294	E300K	300	Missense	distal	6	no	138.400	134.566	EPSD;PhosphoSitePlus	COSMIC	128.034	Down-regulation
AGC_GRK_BARK_GRK2_ST	P08172	CHRM2	P25098	GRK2	T302	D299N	299	Missense	distal	-3	no	163.423	160.145	EPSD;PhosphoSitePlus	COSMIC	128.034	Down-regulation
AGC_GRK_BARK_GRK2_ST	P08172	CHRM2	P25098	GRK2	T302	E300K	300	Missense	proximal	-2	no	163.423	157.914	EPSD;PhosphoSitePlus	COSMIC	128.034	Down-regulation
AGC_GRK_BARK_GRK2_ST	P08172	CHRM2	P25098	GRK2	T302	E305Q	305	Missense	distal	3	no	163.423	156.953	EPSD;PhosphoSitePlus	COSMIC	128.034	Down-regulation
AGC_GRK_BARK_GRK2_ST	P08172	CHRM2	P25098	GRK2	T302	S309F	309	Missense	distal	7	no	163.423	163.586	EPSD;PhosphoSitePlus	COSMIC;GDSC	128.034	Up-regulation
AGC_GRK_BARK_GRK2_ST	P08172	CHRM2	P25098	GRK2	T307	E300K	300	Missense	distal	-7	no	163.633	164.023	EPSD;PhosphoSitePlus	COSMIC	128.034	Up-regulation
AGC_GRK_BARK_GRK2_ST	P08172	CHRM2	P25098	GRK2	T307	E305Q	305	Missense	proximal	-2	no	163.633	159.328	EPSD;PhosphoSitePlus	COSMIC	128.034	Down-regulation
AGC_GRK_BARK_GRK2_ST	P08172	CHRM2	P25098	GRK2	T307	S309F	309	Missense	proximal	2	no	163.633	162.141	EPSD;PhosphoSitePlus	COSMIC;GDSC	128.034	Down-regulation
AGC_GRK_BARK_GRK2_ST	P08172	CHRM2	P25098	GRK2	S309	S315Y	315	Missense	distal	6	no	154.235	154.594	EPSD;PhosphoSitePlus	COSMIC	128.034	Up-regulation
AGC_GRK_BARK_GRK2_ST	P08172	CHRM2	P25098	GRK2	S309	E305Q	305	Missense	distal	-4	no	154.235	149.003	EPSD;PhosphoSitePlus	COSMIC	128.034	Down-regulation
AGC_GRK_BARK_GRK2_ST	P08172	CHRM2	P25098	GRK2	S309	S309F	309	Missense	central	0	yes	154.235	0.000	EPSD;PhosphoSitePlus	COSMIC;GDSC	128.034	Loss
AGC_GRK_BARK_GRK2_ST	P08172	CHRM2	P25098	GRK2	T310	S315Y	315	Missense	distal	5	no	146.879	144.204	EPSD;PhosphoSitePlus	COSMIC	128.034	Down-regulation
AGC_GRK_BARK_GRK2_ST	P08172	CHRM2	P25098	GRK2	T310	E305Q	305	Missense	distal	-5	no	146.879	140.974	EPSD;PhosphoSitePlus	COSMIC	128.034	Down-regulation
AGC_GRK_BARK_GRK2_ST	P08172	CHRM2	P25098	GRK2	T310	S309F	309	Missense	proximal	-1	no	146.879	136.867	EPSD;PhosphoSitePlus	COSMIC;GDSC	128.034	Down-regulation
AGC_GRK_BARK_GRK2_ST	P08172	CHRM2	P25098	GRK2	S311	S315Y	315	Missense	distal	4	no	143.703	138.681	PhosphoSitePlus;EPSD	COSMIC	128.034	Down-regulation
AGC_GRK_BARK_GRK2_ST	P08172	CHRM2	P25098	GRK2	S311	E305Q	305	Missense	distal	-6	no	143.703	144.895	PhosphoSitePlus;EPSD	COSMIC	128.034	Up-regulation
AGC_GRK_BARK_GRK2_ST	P08172	CHRM2	P25098	GRK2	S311	S309F	309	Missense	proximal	-2	no	143.703	122.428	PhosphoSitePlus;EPSD	COSMIC;GDSC	128.034	Loss
AGC_GRK_BARK_GRK2_ST	P08172	CHRM2	P25098	GRK2	S334	K333R	333	Missense	proximal	-1	no	119.458	128.423	EPSD	COSMIC	128.034	Gain
AGC_GRK_BARK_GRK2_ST	P35372	OPRM1	P25098	GRK2	S270	K271N	271	Missense	proximal	1	no	113.838	128.101	EPSD	COSMIC	128.034	Gain
AGC_GRK_BARK_GRK2_ST	P35372	OPRM1	P25098	GRK2	S365	I360T	360	Missense	distal	-5	no	127.521	142.208	EPSD	COSMIC	128.034	Gain
AGC_GRK_BARK_GRK2_ST	P35372	OPRM1	P25098	GRK2	T372	A379S	379	Missense	distal	7	no	146.811	146.950	EPSD	COSMIC	128.034	Up-regulation
AGC_GRK_BARK_GRK2_ST	P35372	OPRM1	P25098	GRK2	T372	P376H	376	Missense	distal	4	no	146.811	145.218	EPSD	COSMIC	128.034	Down-regulation
AGC_GRK_BARK_GRK2_ST	P35372	OPRM1	P25098	GRK2	S377	A379S	379	Missense	proximal	2	no	170.730	173.839	PhosphoSitePlus	COSMIC	128.034	Up-regulation
AGC_GRK_BARK_GRK2_ST	P35372	OPRM1	P25098	GRK2	S377	P376H	376	Missense	proximal	-1	no	170.730	166.859	PhosphoSitePlus	COSMIC	128.034	Down-regulation
AGC_GRK_BARK_GRK2_ST	P35372	OPRM1	P25098	GRK2	T378	A379S	379	Missense	proximal	1	no	163.760	173.892	EPSD	COSMIC	128.034	Up-regulation
AGC_GRK_BARK_GRK2_ST	P35372	OPRM1	P25098	GRK2	T378	P376H	376	Missense	proximal	-2	no	163.760	160.129	EPSD	COSMIC	128.034	Down-regulation
AGC_GRK_BARK_GRK2_ST	P35372	OPRM1	P25098	GRK2	T396	E395K	395	Missense	proximal	-1	no	158.879	147.451	EPSD	COSMIC	128.034	Down-regulation
AGC_GRK_BARK_GRK2_ST	P35372	OPRM1	P25098	GRK2	T396	E390Q	390	Missense	distal	-6	no	158.879	160.070	EPSD	COSMIC	128.034	Up-regulation
AGC_GRK_BARK_GRK2_ST	P35372	OPRM1	P25098	GRK2	T396	E390K	390	Missense	distal	-6	no	158.879	154.181	EPSD	COSMIC	128.034	Down-regulation
AGC_GRK_BARK_GRK2_ST	P35372	OPRM1	P25098	GRK2	T396	A397S	397	Missense	proximal	1	no	158.879	169.011	EPSD	COSMIC	128.034	Up-regulation
AGC_GRK_BARK_GRK2_ST	P35372	OPRM1	P25098	GRK2	T396	L392M	392	Missense	distal	-4	no	158.879	152.798	EPSD	COSMIC	128.034	Down-regulation
AGC_GRK_BARK_GRK2_ST	P35372	OPRM1	P25098	GRK2	T396	A397P	397	Missense	proximal	1	no	158.879	161.850	EPSD	COSMIC	128.034	Up-regulation
AGC_GRK_BARK_GRK2_ST	P35372	OPRM1	P25098	GRK2	T396	A397D	397	Missense	proximal	1	no	158.879	171.303	EPSD	COSMIC	128.034	Up-regulation
AGC_GRK_BARK_GRK2_ST	P35372	OPRM1	P25098	GRK2	T396	L399I	399	Missense	distal	3	no	158.879	153.757	EPSD	COSMIC	128.034	Down-regulation
AGC_GRK_BARK_GRK2_ST	P35367	HRH1	P25098	GRK2	S275	G270E	270	Missense	distal	-5	no	124.894	128.996	EPSD	COSMIC	128.034	Gain
AGC_GRK_BARK_GRK2_ST	P35367	HRH1	P25098	GRK2	S277	G270E	270	Missense	distal	-7	no	132.643	134.685	EPSD	COSMIC	128.034	Up-regulation
AGC_GRK_BARK_GRK2_ST	P35367	HRH1	P25098	GRK2	S277	E282K	282	Missense	distal	5	no	132.643	128.074	EPSD	COSMIC	128.034	Down-regulation
AGC_GRK_BARK_GRK2_ST	P35367	HRH1	P25098	GRK2	S277	M283I	283	Missense	distal	6	no	132.643	131.970	EPSD	COSMIC	128.034	Down-regulation
AGC_GRK_BARK_GRK2_ST	P35367	HRH1	P25098	GRK2	S396	S396P	396	Missense	central	0	yes	137.287	0.000	EPSD	COSMIC	128.034	Loss
AGC_GRK_BARK_GRK2_ST	P35367	HRH1	P25098	GRK2	S396	S403F	403	Missense	distal	7	no	137.287	137.451	EPSD	COSMIC	128.034	Up-regulation
AGC_GRK_BARK_GRK2_ST	P35367	HRH1	P25098	GRK2	S396	R395S	395	Missense	proximal	-1	no	137.287	140.855	EPSD	COSMIC	128.034	Up-regulation
AGC_GRK_BARK_GRK2_ST	P35367	HRH1	P25098	GRK2	S396	R395L	395	Missense	proximal	-1	no	137.287	131.136	EPSD	COSMIC	128.034	Down-regulation
AGC_GRK_BARK_GRK2_ST	P35367	HRH1	P25098	GRK2	S398	G404R	404	Missense	distal	6	no	138.286	139.769	PhosphoSitePlus	COSMIC	128.034	Up-regulation
AGC_GRK_BARK_GRK2_ST	P35367	HRH1	P25098	GRK2	S398	S396P	396	Missense	proximal	-2	no	138.286	134.120	PhosphoSitePlus	COSMIC	128.034	Down-regulation
AGC_GRK_BARK_GRK2_ST	P35367	HRH1	P25098	GRK2	S398	S403F	403	Missense	distal	5	no	138.286	132.772	PhosphoSitePlus	COSMIC	128.034	Down-regulation
AGC_GRK_BARK_GRK2_ST	P35367	HRH1	P25098	GRK2	S398	R395S	395	Missense	distal	-3	no	138.286	132.540	PhosphoSitePlus	COSMIC	128.034	Down-regulation
AGC_GRK_BARK_GRK2_ST	P35367	HRH1	P25098	GRK2	S398	R395L	395	Missense	distal	-3	no	138.286	130.237	PhosphoSitePlus	COSMIC	128.034	Down-regulation
AGC_GRK_BARK_GRK2_ST	P21731	TBXA2R	P25098	GRK2	S324	R322G	322	Missense	proximal	-2	no	131.962	124.799	EPSD	COSMIC;CCLE	128.034	Loss
AGC_GRK_BARK_GRK2_ST	P21731	TBXA2R	P25098	GRK2	S329	R322G	322	Missense	distal	-7	no	136.048	135.247	EPSD	COSMIC;CCLE	128.034	Down-regulation
AGC_GRK_BARK_GRK2_ST	O95398	RAPGEF3	P25098	GRK2	S150	G145R	145	Missense	distal	-5	no	133.869	136.424	EPSD	COSMIC	128.034	Up-regulation
AGC_GRK_BARK_GRK2_ST	O95398	RAPGEF3	P25098	GRK2	S150	C156F	156	Missense	distal	6	no	133.869	127.646	EPSD	COSMIC	128.034	Loss
AGC_GRK_BARK_GRK2_ST	O95398	RAPGEF3	P25098	GRK2	S150	Q157E	157	Missense	distal	7	no	133.869	134.197	EPSD	COSMIC	128.034	Up-regulation
AGC_GRK_BARK_GRK2_ST	O95398	RAPGEF3	P25098	GRK2	S209	R211Q	211	Missense	proximal	2	no	136.662	136.497	EPSD	COSMIC;CCLE	128.034	Down-regulation
AGC_GRK_BARK_GRK2_ST	O95398	RAPGEF3	P25098	GRK2	S209	A206V	206	Missense	distal	-3	no	136.662	137.674	EPSD	COSMIC	128.034	Up-regulation
AGC_GRK_BARK_GRK2_ST	O95398	RAPGEF3	P25098	GRK2	S209	A204T	204	Missense	distal	-5	no	136.662	144.159	EPSD	COSMIC	128.034	Up-regulation
AGC_GRK_BARK_GRK2_ST	O95398	RAPGEF3	P25098	GRK2	S370	P375L	375	Missense	distal	5	no	138.681	135.106	EPSD	COSMIC	128.034	Down-regulation
AGC_GRK_BARK_GRK2_ST	O95398	RAPGEF3	P25098	GRK2	S370	R377Q	377	Missense	distal	7	no	138.681	138.336	EPSD	COSMIC	128.034	Down-regulation
AGC_GRK_BARK_GRK2_ST	O95398	RAPGEF3	P25098	GRK2	S370	R368K	368	Missense	proximal	-2	no	138.681	140.182	EPSD	COSMIC	128.034	Up-regulation
AGC_GRK_BARK_GRK2_ST	O95398	RAPGEF3	P25098	GRK2	T380	P375L	375	Missense	distal	-5	no	128.646	124.624	EPSD	COSMIC	128.034	Loss
AGC_GRK_BARK_GRK2_ST	O95398	RAPGEF3	P25098	GRK2	T380	R377Q	377	Missense	distal	-3	no	128.646	129.776	EPSD	COSMIC	128.034	Up-regulation
AGC_GRK_BARK_GRK2_ST	O95398	RAPGEF3	P25098	GRK2	S915	S918F	918	Missense	distal	3	no	141.113	139.269	EPSD	COSMIC	128.034	Down-regulation
AGC_GRK_BARK_GRK2_ST	O95398	RAPGEF3	P25098	GRK2	S918	S918F	918	Missense	central	0	yes	129.954	0.000	EPSD	COSMIC	128.034	Loss
AGC_GRK_BARK_GRK2_ST	P09497	CLTB	P25098	GRK2	T190	S183Y	183	Missense	distal	-7	no	137.183	143.559	EPSD	COSMIC	128.034	Up-regulation
AGC_GRK_BARK_GRK2_ST	P09497	CLTB	P25098	GRK2	T190	E186K	186	Missense	distal	-4	no	137.183	132.091	EPSD	COSMIC	128.034	Down-regulation
AGC_GRK_BARK_GRK2_ST	P09497	CLTB	P25098	GRK2	T190	W192L	192	Missense	proximal	2	no	137.183	139.564	EPSD	COSMIC	128.034	Up-regulation
AGC_GRK_BARK_GRK2_ST	P09497	CLTB	P25098	GRK2	S205	S205N	205	Missense	central	0	yes	173.206	0.000	PhosphoSitePlus	COSMIC	128.034	Loss
AGC_GRK_BARK_GRK2_ST	P09497	CLTB	P25098	GRK2	S221	T225M	225	Missense	distal	4	no	127.893	132.644	EPSD	COSMIC	128.034	Gain
AGC_GRK_BARK_GRK2_ST	P09497	CLTB	P25098	GRK2	S221	L227P	227	Missense	distal	6	no	127.893	130.124	EPSD	COSMIC	128.034	Gain
AGC_GRK_BARK_GRK2_ST	P09497	CLTB	P25098	GRK2	T225	T225M	225	Missense	central	0	yes	137.440	0.000	EPSD	COSMIC	128.034	Loss
AGC_GRK_BARK_GRK2_ST	P09497	CLTB	P25098	GRK2	T225	L227P	227	Missense	proximal	2	no	137.440	142.383	EPSD	COSMIC	128.034	Up-regulation
AGC_GRK_BARK_GRK2_ST	P09497	CLTB	P25098	GRK2	S228	T225M	225	Missense	distal	-3	no	150.885	148.770	EPSD	COSMIC	128.034	Down-regulation
AGC_GRK_BARK_GRK2_ST	P09497	CLTB	P25098	GRK2	S228	L227P	227	Missense	proximal	-1	no	150.885	164.542	EPSD	COSMIC	128.034	Up-regulation
AGC_GRK_BARK_GRK2_ST	Q16539	MAPK14	P25098	GRK2	S28	Y35H	35	Missense	distal	7	no	132.395	133.210	EPSD	COSMIC	128.034	Up-regulation
AGC_GRK_BARK_GRK2_ST	Q16539	MAPK14	P25098	GRK2	S28	A34T	34	Missense	distal	6	no	132.395	133.184	EPSD	COSMIC	128.034	Up-regulation
AGC_GRK_BARK_GRK2_ST	Q16539	MAPK14	P25098	GRK2	S28	G33A	33	Missense	distal	5	no	132.395	130.561	EPSD	COSMIC	128.034	Down-regulation
AGC_GRK_BARK_GRK2_ST	Q16539	MAPK14	P25098	GRK2	T123	K121T	121	Missense	proximal	-2	no	134.208	134.563	PhosphoSitePlus	COSMIC;GDSC;CCLE	128.034	Up-regulation
AGC_GRK_BARK_GRK2_ST	Q16539	MAPK14	P25098	GRK2	S326	P322R	322	Missense	distal	-4	no	133.019	134.216	EPSD	COSMIC;CCLE	128.034	Up-regulation
AGC_GRK_BARK_GRK2_ST	Q16539	MAPK14	P25098	GRK2	S326	V319L	319	Missense	distal	-7	no	133.019	134.899	EPSD	COSMIC	128.034	Up-regulation
AGC_GRK_BARK_GRK2_ST	P26038	MSN	P25098	GRK2	S74	R71W	71	Missense	distal	-3	no	123.424	130.847	EPSD	COSMIC	128.034	Gain
AGC_GRK_BARK_GRK2_ST	P26038	MSN	P25098	GRK2	S90	I97T	97	Missense	distal	7	no	131.598	131.161	EPSD	COSMIC	128.034	Down-regulation
AGC_GRK_BARK_GRK2_ST	P26038	MSN	P25098	GRK2	S90	S90F	90	Missense	central	0	yes	131.598	0.000	EPSD	COSMIC	128.034	Loss
AGC_GRK_BARK_GRK2_ST	P26038	MSN	P25098	GRK2	S90	D96Y	96	Missense	distal	6	no	131.598	131.720	EPSD	COSMIC	128.034	Up-regulation
AGC_GRK_BARK_GRK2_ST	P26038	MSN	P25098	GRK2	S207	S214L	214	Missense	distal	7	no	133.374	134.031	EPSD	COSMIC	128.034	Up-regulation
AGC_GRK_BARK_GRK2_ST	P26038	MSN	P25098	GRK2	S384	K380R	380	Missense	distal	-4	no	139.602	137.667	EPSD	COSMIC	128.034	Down-regulation
AGC_GRK_BARK_GRK2_ST	P26038	MSN	P25098	GRK2	T413	K411E	411	Missense	proximal	-2	no	124.677	130.186	EPSD	COSMIC	128.034	Gain
AGC_GRK_BARK_GRK2_ST	P26038	MSN	P25098	GRK2	T510	K514M	514	Missense	distal	4	no	128.394	133.740	EPSD	COSMIC	128.034	Up-regulation
AGC_GRK_BARK_GRK2_ST	P26038	MSN	P25098	GRK2	T510	R508H	508	Missense	proximal	-2	no	128.394	126.901	EPSD	COSMIC	128.034	Loss
AGC_GRK_BARK_GRK2_ST	P26038	MSN	P25098	GRK2	T510	N515K	515	Missense	distal	5	no	128.394	130.452	EPSD	COSMIC	128.034	Up-regulation
AGC_GRK_BARK_GRK2_ST	P26038	MSN	P25098	GRK2	T558	R560H	560	Missense	proximal	2	no	164.331	158.728	PhosphoSitePlus	COSMIC;GDSC;CCLE	128.034	Down-regulation
AGC_GRK_BARK_GRK2_ST	P26038	MSN	P25098	GRK2	T558	K555R	555	Missense	distal	-3	no	164.331	174.676	PhosphoSitePlus	COSMIC	128.034	Up-regulation
AGC_GRK_BARK_GRK2_ST	P26038	MSN	P25098	GRK2	T567	R560H	560	Missense	distal	-7	no	144.054	138.464	EPSD	COSMIC;GDSC;CCLE	128.034	Down-regulation
AGC_GRK_BARK_GRK2_ST	P26038	MSN	P25098	GRK2	T567	D572E	572	Missense	distal	5	no	144.054	144.783	EPSD	COSMIC	128.034	Up-regulation
AGC_GRK_BARK_GRK2_ST	P26038	MSN	P25098	GRK2	T567	R570H	570	Missense	distal	3	no	144.054	143.283	EPSD	COSMIC	128.034	Down-regulation
AGC_GRK_BARK_GRK2_ST	P26038	MSN	P25098	GRK2	S576	D572E	572	Missense	distal	-4	no	157.522	147.781	EPSD	COSMIC	128.034	Down-regulation
AGC_GRK_BARK_GRK2_ST	P26038	MSN	P25098	GRK2	S576	R570H	570	Missense	distal	-6	no	157.522	155.543	EPSD	COSMIC	128.034	Down-regulation
AGC_GRK_BARK_GRK2_ST	Q96A54	ADIPOR1	P25098	GRK2	S7	Q11H	11	Missense	distal	4	no	146.400	140.840	EPSD;PhosphoSitePlus	COSMIC	128.034	Down-regulation
AGC_GRK_BARK_GRK2_ST	Q96A54	ADIPOR1	P25098	GRK2	T24	V25G	25	Missense	proximal	1	no	149.710	142.103	PhosphoSitePlus;EPSD	COSMIC	128.034	Down-regulation
AGC_GRK_BARK_GRK2_ST	Q96A54	ADIPOR1	P25098	GRK2	T24	D23H	23	Missense	proximal	-1	no	149.710	145.379	PhosphoSitePlus;EPSD	COSMIC	128.034	Down-regulation
AGC_GRK_BARK_GRK2_ST	Q96A54	ADIPOR1	P25098	GRK2	T53	K47N	47	Missense	distal	-6	no	143.691	148.902	EPSD;PhosphoSitePlus	COSMIC	128.034	Up-regulation
AGC_GRK_BARK_GRK2_ST	Q15796	SMAD2	P25098	GRK2	S118	R114C	114	Missense	distal	-4	no	126.519	130.763	EPSD	COSMIC	128.034	Gain
AGC_GRK_BARK_GRK2_ST	Q15796	SMAD2	P25098	GRK2	S118	G122R	122	Missense	distal	4	no	126.519	130.958	EPSD	COSMIC	128.034	Gain
AGC_GRK_BARK_GRK2_ST	Q15796	SMAD2	P25098	GRK2	T197	H198N	198	Missense	proximal	1	no	143.095	140.805	PhosphoSitePlus	COSMIC	128.034	Down-regulation
AGC_GRK_BARK_GRK2_ST	Q15796	SMAD2	P25098	GRK2	T197	S199F	199	Missense	proximal	2	no	143.095	141.602	PhosphoSitePlus	COSMIC	128.034	Down-regulation
AGC_GRK_BARK_GRK2_ST	Q15796	SMAD2	P25098	GRK2	T197	H198D	198	Missense	proximal	1	no	143.095	142.240	PhosphoSitePlus	COSMIC	128.034	Down-regulation
AGC_GRK_BARK_GRK2_ST	Q15796	SMAD2	P25098	GRK2	T197	D195H	195	Missense	proximal	-2	no	143.095	131.386	PhosphoSitePlus	COSMIC	128.034	Down-regulation
AGC_GRK_BARK_GRK2_ST	Q15796	SMAD2	P25098	GRK2	T197	P191S	191	Missense	distal	-6	no	143.095	149.263	PhosphoSitePlus	COSMIC	128.034	Up-regulation
AGC_GRK_BARK_GRK2_ST	Q15796	SMAD2	P25098	GRK2	S240	D242E	242	Missense	proximal	2	no	126.684	129.185	EPSD	COSMIC	128.034	Gain
AGC_GRK_BARK_GRK2_ST	Q15796	SMAD2	P25098	GRK2	S245	L249V	249	Missense	distal	4	no	124.249	139.414	EPSD	COSMIC	128.034	Gain
AGC_GRK_BARK_GRK2_ST	Q15796	SMAD2	P25098	GRK2	S245	S240R	240	Missense	distal	-5	no	124.249	129.018	EPSD	COSMIC	128.034	Gain
AGC_GRK_BARK_GRK2_ST	Q15796	SMAD2	P25098	GRK2	S351	A354T	354	Missense	distal	3	no	127.717	129.255	EPSD	COSMIC	128.034	Gain
AGC_GRK_BARK_GRK2_ST	Q15796	SMAD2	P25098	GRK2	S351	I355M	355	Missense	distal	4	no	127.717	132.516	EPSD	COSMIC	128.034	Gain
AGC_GRK_BARK_GRK2_ST	Q15796	SMAD2	P25098	GRK2	S351	A354P	354	Missense	distal	3	no	127.717	132.031	EPSD	COSMIC	128.034	Gain
AGC_GRK_BARK_GRK2_ST	Q15796	SMAD2	P25098	GRK2	S351	E344K	344	Missense	distal	-7	no	127.717	128.107	EPSD	COSMIC	128.034	Gain
AGC_GRK_BARK_GRK2_ST	Q15796	SMAD2	P25098	GRK2	S351	F346V	346	Missense	distal	-5	no	127.717	138.247	EPSD	COSMIC	128.034	Gain
AGC_GRK_BARK_GRK2_ST	Q15796	SMAD2	P25098	GRK2	S458	P459H	459	Missense	proximal	1	no	122.515	132.823	EPSD	COSMIC	128.034	Gain
AGC_GRK_BARK_GRK2_ST	Q15796	SMAD2	P25098	GRK2	S460	R462C	462	Missense	proximal	2	no	143.401	140.556	EPSD	COSMIC;GDSC;CCLE	128.034	Down-regulation
AGC_GRK_BARK_GRK2_ST	Q15796	SMAD2	P25098	GRK2	S460	C463F	463	Missense	distal	3	no	143.401	136.629	EPSD	COSMIC	128.034	Down-regulation
AGC_GRK_BARK_GRK2_ST	Q15796	SMAD2	P25098	GRK2	S460	G457R	457	Missense	distal	-3	no	143.401	149.637	EPSD	COSMIC	128.034	Up-regulation
AGC_GRK_BARK_GRK2_ST	Q15796	SMAD2	P25098	GRK2	S460	S465I	465	Missense	distal	5	no	143.401	138.888	EPSD	COSMIC	128.034	Down-regulation
AGC_GRK_BARK_GRK2_ST	Q15796	SMAD2	P25098	GRK2	S460	C463Y	463	Missense	distal	3	no	143.401	139.768	EPSD	COSMIC	128.034	Down-regulation
AGC_GRK_BARK_GRK2_ST	Q15796	SMAD2	P25098	GRK2	S460	S465N	465	Missense	distal	5	no	143.401	138.453	EPSD	COSMIC;GDSC;CCLE	128.034	Down-regulation
AGC_GRK_BARK_GRK2_ST	Q15796	SMAD2	P25098	GRK2	S460	P459H	459	Missense	proximal	-1	no	143.401	139.531	EPSD	COSMIC	128.034	Down-regulation
AGC_GRK_BARK_GRK2_ST	Q15796	SMAD2	P25098	GRK2	S460	S465R	465	Missense	distal	5	no	143.401	141.305	EPSD	COSMIC	128.034	Down-regulation
AGC_GRK_BARK_GRK2_ST	Q15796	SMAD2	P25098	GRK2	S460	S464L	464	Missense	distal	4	no	143.401	129.572	EPSD	COSMIC	128.034	Down-regulation
AGC_GRK_BARK_GRK2_ST	Q15796	SMAD2	P25098	GRK2	S464	C463Y	463	Missense	proximal	-1	no	123.290	129.578	EPSD	COSMIC	128.034	Gain
AGC_GRK_BARK_GRK2_ST	Q15796	SMAD2	P25098	GRK2	S465	C463Y	463	Missense	proximal	-2	no	125.519	141.580	EPSD	COSMIC	128.034	Gain
AGC_GRK_BARK_GRK2_ST	Q15796	SMAD2	P25098	GRK2	S465	P459H	459	Missense	distal	-6	no	125.519	128.136	EPSD	COSMIC	128.034	Gain
AGC_GRK_BARK_GRK2_ST	Q15796	SMAD2	P25098	GRK2	S467	R462C	462	Missense	distal	-5	no	153.772	146.352	EPSD	COSMIC;GDSC;CCLE	128.034	Down-regulation
AGC_GRK_BARK_GRK2_ST	Q15796	SMAD2	P25098	GRK2	S467	C463F	463	Missense	distal	-4	no	153.772	150.140	EPSD	COSMIC	128.034	Down-regulation
AGC_GRK_BARK_GRK2_ST	Q15796	SMAD2	P25098	GRK2	S467	S465I	465	Missense	proximal	-2	no	153.772	137.798	EPSD	COSMIC	128.034	Down-regulation
AGC_GRK_BARK_GRK2_ST	Q15796	SMAD2	P25098	GRK2	S467	C463Y	463	Missense	distal	-4	no	153.772	162.607	EPSD	COSMIC	128.034	Up-regulation
AGC_GRK_BARK_GRK2_ST	Q15796	SMAD2	P25098	GRK2	S467	S465N	465	Missense	proximal	-2	no	153.772	152.591	EPSD	COSMIC;GDSC;CCLE	128.034	Down-regulation
AGC_GRK_BARK_GRK2_ST	Q15796	SMAD2	P25098	GRK2	S467	S465R	465	Missense	proximal	-2	no	153.772	147.467	EPSD	COSMIC	128.034	Down-regulation
AGC_GRK_BARK_GRK2_ST	Q15796	SMAD2	P25098	GRK2	S467	S464L	464	Missense	distal	-3	no	153.772	151.469	EPSD	COSMIC	128.034	Down-regulation
AGC_GRK_BARK_GRK2_ST	P08069	IGF1R	P25098	GRK2	T466	G467E	467	Missense	proximal	1	no	111.242	128.436	EPSD	COSMIC	128.034	Gain
AGC_GRK_BARK_GRK2_ST	P08069	IGF1R	P25098	GRK2	T468	K469N	469	Missense	proximal	1	no	119.556	133.819	EPSD	COSMIC	128.034	Gain
AGC_GRK_BARK_GRK2_ST	P08069	IGF1R	P25098	GRK2	S609	R605H	605	Missense	distal	-4	no	129.653	121.249	EPSD	COSMIC	128.034	Loss
AGC_GRK_BARK_GRK2_ST	P08069	IGF1R	P25098	GRK2	S609	P614L	614	Missense	distal	5	no	129.653	126.078	EPSD	COSMIC	128.034	Loss
AGC_GRK_BARK_GRK2_ST	P08069	IGF1R	P25098	GRK2	S609	S612P	612	Missense	distal	3	no	129.653	132.651	EPSD	COSMIC	128.034	Up-regulation
AGC_GRK_BARK_GRK2_ST	P08069	IGF1R	P25098	GRK2	S609	Y603C	603	Missense	distal	-6	no	129.653	123.225	EPSD	COSMIC	128.034	Loss
AGC_GRK_BARK_GRK2_ST	P08069	IGF1R	P25098	GRK2	S609	R605S	605	Missense	distal	-4	no	129.653	138.041	EPSD	COSMIC	128.034	Up-regulation
AGC_GRK_BARK_GRK2_ST	P08069	IGF1R	P25098	GRK2	S609	P614T	614	Missense	distal	5	no	129.653	128.690	EPSD	COSMIC	128.034	Down-regulation
AGC_GRK_BARK_GRK2_ST	P08069	IGF1R	P25098	GRK2	S609	P614S	614	Missense	distal	5	no	129.653	131.848	EPSD	COSMIC	128.034	Up-regulation
AGC_GRK_BARK_GRK2_ST	P08069	IGF1R	P25098	GRK2	S1193	G1199R	1199	Missense	distal	6	no	132.846	134.329	EPSD	COSMIC	128.034	Up-regulation
AGC_GRK_BARK_GRK2_ST	P08069	IGF1R	P25098	GRK2	S1193	S1197Y	1197	Missense	distal	4	no	132.846	127.823	EPSD	COSMIC	128.034	Loss
AGC_GRK_BARK_GRK2_ST	P08069	IGF1R	P25098	GRK2	S1193	S1197F	1197	Missense	distal	4	no	132.846	123.859	EPSD	COSMIC	128.034	Loss
AGC_GRK_BARK_GRK2_ST	P08069	IGF1R	P25098	GRK2	S1278	R1275Q	1275	Missense	distal	-3	no	142.710	143.840	PhosphoSitePlus	COSMIC	128.034	Up-regulation
AGC_GRK_BARK_GRK2_ST	P08069	IGF1R	P25098	GRK2	S1278	S1282I	1282	Missense	distal	4	no	142.710	137.346	PhosphoSitePlus	COSMIC	128.034	Down-regulation
AGC_GRK_BARK_GRK2_ST	P08069	IGF1R	P25098	GRK2	S1278	E1284K	1284	Missense	distal	6	no	142.710	138.875	PhosphoSitePlus	COSMIC	128.034	Down-regulation
AGC_GRK_BARK_GRK2_ST	P08069	IGF1R	P25098	GRK2	S1278	S1282R	1282	Missense	distal	4	no	142.710	143.774	PhosphoSitePlus	COSMIC	128.034	Up-regulation
AGC_GRK_BARK_GRK2_ST	P08069	IGF1R	P25098	GRK2	S1278	P1272T	1272	Missense	distal	-6	no	142.710	147.949	PhosphoSitePlus	COSMIC	128.034	Up-regulation
AGC_GRK_BARK_GRK2_ST	P08069	IGF1R	P25098	GRK2	S1278	R1275W	1275	Missense	distal	-3	no	142.710	150.133	PhosphoSitePlus	COSMIC	128.034	Up-regulation
AGC_GRK_BARK_GRK2_ST	P08069	IGF1R	P25098	GRK2	S1278	E1276D	1276	Missense	proximal	-2	no	142.710	145.916	PhosphoSitePlus	COSMIC	128.034	Up-regulation
AGC_GRK_BARK_GRK2_ST	P08069	IGF1R	P25098	GRK2	S1278	E1283K	1283	Missense	distal	5	no	142.710	138.141	PhosphoSitePlus	COSMIC	128.034	Down-regulation
AGC_GRK_BARK_GRK2_ST	P08069	IGF1R	P25098	GRK2	S1339	S1339C	1339	Missense	central	0	yes	131.255	0.000	EPSD	COSMIC	128.034	Loss
AGC_GRK_BARK_GRK2_ST	P08069	IGF1R	P25098	GRK2	S1339	R1337C	1337	Missense	proximal	-2	no	131.255	123.719	EPSD	COSMIC;GDSC	128.034	Loss
AGC_GRK_BARK_GRK2_ST	P08069	IGF1R	P25098	GRK2	S1339	A1338T	1338	Missense	proximal	-1	no	131.255	129.372	EPSD	COSMIC	128.034	Down-regulation
AGC_GRK_BARK_GRK2_ST	P08069	IGF1R	P25098	GRK2	S1339	D1341N	1341	Missense	proximal	2	no	131.255	129.470	EPSD	COSMIC;GDSC	128.034	Down-regulation
AGC_GRK_BARK_GRK2_ST	P08069	IGF1R	P25098	GRK2	S1339	A1338S	1338	Missense	proximal	-1	no	131.255	143.373	EPSD	COSMIC	128.034	Up-regulation
AGC_GRK_BARK_GRK2_ST	P08069	IGF1R	P25098	GRK2	S1364	R1357Q	1357	Missense	distal	-7	no	145.142	143.315	EPSD	COSMIC	128.034	Down-regulation
AGC_GRK_BARK_GRK2_ST	P08069	IGF1R	P25098	GRK2	S1364	R1357L	1357	Missense	distal	-7	no	145.142	144.600	EPSD	COSMIC	128.034	Down-regulation
AGC_GRK_BARK_GRK2_ST	P08069	IGF1R	P25098	GRK2	S1364	T1366P	1366	Missense	proximal	2	no	145.142	148.181	EPSD	COSMIC	128.034	Up-regulation
AGC_GRK_BARK_GRK2_ST	P08069	IGF1R	P25098	GRK2	S1364	S1365W	1365	Missense	proximal	1	no	145.142	127.075	EPSD	COSMIC	128.034	Loss
AGC_GRK_BARK_GRK2_ST	P08069	IGF1R	P25098	GRK2	S1364	S1365L	1365	Missense	proximal	1	no	145.142	140.030	EPSD	COSMIC	128.034	Down-regulation
AGC_GRK_BARK_GRK2_ST	P08069	IGF1R	P25098	GRK2	S1364	S1364W	1364	Missense	central	0	yes	145.142	0.000	EPSD	COSMIC	128.034	Loss
AGC_GRK_BARK_GRK2_ST	P08069	IGF1R	P25098	GRK2	S1365	T1366P	1366	Missense	proximal	1	no	138.645	139.484	EPSD	COSMIC	128.034	Up-regulation
AGC_GRK_BARK_GRK2_ST	P08069	IGF1R	P25098	GRK2	S1365	S1365W	1365	Missense	central	0	yes	138.645	0.000	EPSD	COSMIC	128.034	Loss
AGC_GRK_BARK_GRK2_ST	P08069	IGF1R	P25098	GRK2	S1365	S1365L	1365	Missense	central	0	yes	138.645	0.000	EPSD	COSMIC	128.034	Loss
AGC_GRK_BARK_GRK2_ST	P08069	IGF1R	P25098	GRK2	S1365	S1364W	1364	Missense	proximal	-1	no	138.645	122.918	EPSD	COSMIC	128.034	Loss
AGC_GRK_BARK_GRK2_ST	P08069	IGF1R	P25098	GRK2	T1366	T1366P	1366	Missense	central	0	yes	136.759	0.000	EPSD	COSMIC	128.034	Loss
AGC_GRK_BARK_GRK2_ST	P08069	IGF1R	P25098	GRK2	T1366	S1365W	1365	Missense	proximal	-1	no	136.759	121.032	EPSD	COSMIC	128.034	Loss
AGC_GRK_BARK_GRK2_ST	P08069	IGF1R	P25098	GRK2	T1366	S1365L	1365	Missense	proximal	-1	no	136.759	127.040	EPSD	COSMIC	128.034	Loss
AGC_GRK_BARK_GRK2_ST	P08069	IGF1R	P25098	GRK2	T1366	S1364W	1364	Missense	proximal	-2	no	136.759	116.639	EPSD	COSMIC	128.034	Loss
AGC_GRK_BARK_GRK2_ST	O60353	FZD6	P25098	GRK2	S641	G637D	637	Missense	distal	-4	no	116.689	135.313	EPSD	COSMIC	128.034	Gain
AGC_GRK_BARK_GRK2_ST	O60353	FZD6	P25098	GRK2	S643	G637D	637	Missense	distal	-6	no	123.061	129.938	EPSD	COSMIC	128.034	Gain
AGC_GRK_BARK_GRK2_ST	O60353	FZD6	P25098	GRK2	S645	R647Q	647	Missense	proximal	2	no	141.936	141.771	EPSD	COSMIC;CCLE	128.034	Down-regulation
AGC_GRK_BARK_GRK2_ST	O60353	FZD6	P25098	GRK2	S648	R647Q	647	Missense	proximal	-1	no	131.612	130.954	PhosphoSitePlus	COSMIC;CCLE	128.034	Down-regulation
AGC_GRK_BARK_GRK2_ST	O60353	FZD6	P25098	GRK2	S673	P677S	677	Missense	distal	4	no	152.074	155.090	EPSD	COSMIC	128.034	Up-regulation
AGC_GRK_BARK_GRK2_ST	O60353	FZD6	P25098	GRK2	S675	P677S	677	Missense	proximal	2	no	132.040	131.763	EPSD	COSMIC	128.034	Down-regulation
AGC_GRK_BARK_GRK2_ST	O60353	FZD6	P25098	GRK2	S678	P677S	677	Missense	proximal	-1	no	170.997	167.060	EPSD	COSMIC	128.034	Down-regulation
AGC_GRK_BARK_GRK2_ST	O60353	FZD6	P25098	GRK2	S679	P677S	677	Missense	proximal	-2	no	161.961	166.127	EPSD	COSMIC	128.034	Up-regulation
AGC_GRK_BARK_GRK2_ST	O60353	FZD6	P25098	GRK2	T684	P677S	677	Missense	distal	-7	no	132.339	129.034	EPSD	COSMIC	128.034	Down-regulation
AGC_GRK_BARK_GRK2_ST	P37840	SNCA	P25098	GRK2	S129	A124S	124	Missense	distal	-5	no	184.693	186.801	PhosphoSitePlus	COSMIC	128.034	Up-regulation
AGC_GRK_BARK_GRK2_ST	P37840	SNCA	P25098	GRK2	S129	E130V	130	Missense	proximal	1	no	184.693	175.105	PhosphoSitePlus	COSMIC	128.034	Down-regulation
AGC_GRK_BARK_GRK2_ST	P37840	SNCA	P25098	GRK2	S129	D135E	135	Missense	distal	6	no	184.693	186.830	PhosphoSitePlus	COSMIC;GDSC;CCLE	128.034	Up-regulation
AGC_GRK_BARK_GRK2_ST	P37840	SNCA	P25098	GRK2	S129	E130A	130	Missense	proximal	1	no	184.693	170.467	PhosphoSitePlus	COSMIC	128.034	Down-regulation
AGC_GRK_BARK_GRK2_ST	P37840	SNCA	P25098	GRK2	S129	E123K	123	Missense	distal	-6	no	184.693	179.995	PhosphoSitePlus	COSMIC	128.034	Down-regulation
STE_STE11_MEKK2_MAP3K2_ST	P35222	CTNNB1	Q9Y2U5	MAP3K2	T41	H36R	36	Missense	distal	-5	no	1.875	2.092	EPSD	COSMIC	2.079	Gain
STE_STE11_MEKK2_MAP3K2_ST	P35222	CTNNB1	Q9Y2U5	MAP3K2	T41	H36Y	36	Missense	distal	-5	no	1.875	2.088	EPSD	COSMIC	2.079	Gain
STE_STE11_MEKK2_MAP3K2_ST	P35222	CTNNB1	Q9Y2U5	MAP3K2	T41	L46P	46	Missense	distal	5	no	1.875	2.098	EPSD	COSMIC	2.079	Gain
STE_STE11_MEKK2_MAP3K2_ST	P35222	CTNNB1	Q9Y2U5	MAP3K2	T41	G38P	38	Missense	distal	-3	no	1.875	2.107	EPSD	COSMIC	2.079	Gain
STE_STE11_MEKK2_MAP3K2_ST	P35222	CTNNB1	Q9Y2U5	MAP3K2	T201	N206H	206	Missense	distal	5	no	2.215	2.174	EPSD	COSMIC	2.079	Down-regulation
STE_STE11_MEKK2_MAP3K2_ST	P35222	CTNNB1	Q9Y2U5	MAP3K2	T201	N206Y	206	Missense	distal	5	no	2.215	2.137	EPSD	COSMIC	2.079	Down-regulation
STE_STE11_MEKK2_MAP3K2_ST	P35222	CTNNB1	Q9Y2U5	MAP3K2	T201	R200H	200	Missense	proximal	-1	no	2.215	2.101	EPSD	COSMIC	2.079	Down-regulation
STE_STE11_MEKK2_MAP3K2_ST	P35222	CTNNB1	Q9Y2U5	MAP3K2	T201	I198L	198	Missense	distal	-3	no	2.215	2.162	EPSD	COSMIC	2.079	Down-regulation
STE_STE11_MEKK2_MAP3K2_ST	P35222	CTNNB1	Q9Y2U5	MAP3K2	T201	R200C	200	Missense	proximal	-1	no	2.215	2.157	EPSD	COSMIC	2.079	Down-regulation
STE_STE11_MEKK2_MAP3K2_ST	P35222	CTNNB1	Q9Y2U5	MAP3K2	S250	T257I	257	Missense	distal	7	no	2.008	2.087	EPSD	COSMIC	2.079	Gain
STE_STE11_MEKK2_MAP3K2_ST	P35222	CTNNB1	Q9Y2U5	MAP3K2	S250	G245A	245	Missense	distal	-5	no	2.008	2.200	EPSD	COSMIC;GDSC	2.079	Gain
STE_STE11_MEKK2_MAP3K2_ST	P35222	CTNNB1	Q9Y2U5	MAP3K2	S250	G245D	245	Missense	distal	-5	no	2.008	2.136	EPSD	COSMIC	2.079	Gain
STE_STE11_MEKK2_MAP3K2_ST	P35222	CTNNB1	Q9Y2U5	MAP3K2	T653	L659S	659	Missense	distal	6	no	1.982	2.176	EPSD	COSMIC	2.079	Gain
STE_STE11_MEKK2_MAP3K2_ST	P35222	CTNNB1	Q9Y2U5	MAP3K2	S675	R673W	673	Missense	proximal	-2	no	4.783	4.786	PhosphoSitePlus	COSMIC	2.079	Up-regulation
STE_STE11_MEKK2_MAP3K2_ST	P35222	CTNNB1	Q9Y2U5	MAP3K2	S675	S680I	680	Missense	distal	5	no	4.783	4.642	PhosphoSitePlus	COSMIC	2.079	Down-regulation
STE_STE11_MEKK2_MAP3K2_ST	P35222	CTNNB1	Q9Y2U5	MAP3K2	S675	E677D	677	Missense	proximal	2	no	4.783	4.824	PhosphoSitePlus	COSMIC	2.079	Up-regulation
STE_STE11_MEKK2_MAP3K2_ST	P35222	CTNNB1	Q9Y2U5	MAP3K2	S675	R673H	673	Missense	proximal	-2	no	4.783	4.787	PhosphoSitePlus	COSMIC	2.079	Up-regulation
STE_STE11_MEKK2_MAP3K2_ST	P35222	CTNNB1	Q9Y2U5	MAP3K2	S675	L678F	678	Missense	distal	3	no	4.783	4.815	PhosphoSitePlus	COSMIC	2.079	Up-regulation
STE_STE11_MEKK2_MAP3K2_ST	P35222	CTNNB1	Q9Y2U5	MAP3K2	S675	R673C	673	Missense	proximal	-2	no	4.783	4.785	PhosphoSitePlus	COSMIC	2.079	Up-regulation
STE_STE11_MEKK2_MAP3K2_ST	Q14653	IRF3	Q9Y2U5	MAP3K2	S173	Q169R	169	Missense	distal	-4	no	5.380	5.390	PhosphoSitePlus	COSMIC;CCLE	2.079	Up-regulation
STE_STE11_MEKK2_MAP3K2_ST	Q14653	IRF3	Q9Y2U5	MAP3K2	S173	P166S	166	Missense	distal	-7	no	5.380	5.390	PhosphoSitePlus	COSMIC	2.079	Up-regulation
STE_STE11_MEKK2_MAP3K2_ST	Q14653	IRF3	Q9Y2U5	MAP3K2	S339	G335E	335	Missense	distal	-4	no	2.120	2.094	EPSD	COSMIC	2.079	Down-regulation
STE_STE11_MEKK2_MAP3K2_ST	Q14653	IRF3	Q9Y2U5	MAP3K2	S339	R341C	341	Missense	proximal	2	no	2.120	1.990	EPSD	COSMIC	2.079	Loss
STE_STE11_MEKK2_MAP3K2_ST	Q14653	IRF3	Q9Y2U5	MAP3K2	S339	G335V	335	Missense	distal	-4	no	2.120	2.059	EPSD	COSMIC	2.079	Loss
STE_STE7_MEK1_MAP2K2_ST	P27361	MAPK3	P36507	MAP2K2	T202	G199D	199	Missense	distal	-3	no	11.021	11.115	PhosphoSitePlus;EPSD	COSMIC	1.900	Up-regulation
STE_STE7_MEK1_MAP2K2_ST	P27361	MAPK3	P36507	MAP2K2	T202	T202M	202	Missense	central	0	yes	11.021	0.000	PhosphoSitePlus;EPSD	COSMIC	1.900	Loss
STE_STE7_MEK1_MAP2K2_ST	P27361	MAPK3	P36507	MAP2K2	T202	Y204C	204	Missense	proximal	2	no	11.021	11.047	PhosphoSitePlus;EPSD	COSMIC	1.900	Up-regulation
STE_STE7_MEK1_MAP2K2_ST	P27361	MAPK3	P36507	MAP2K2	T202	L201P	201	Missense	proximal	-1	no	11.021	10.631	PhosphoSitePlus;EPSD	COSMIC	1.900	Down-regulation
STE_STE7_MEK1_MAP2K2_ST	P05787	KRT8	P36507	MAP2K2	S71	S71R	71	Missense	central	0	yes	2.947	0.000	EPSD	COSMIC	1.900	Loss
STE_STE7_MEK1_MAP2K2_ST	P05787	KRT8	P36507	MAP2K2	S71	S71I	71	Missense	central	0	yes	2.947	0.000	EPSD	COSMIC	1.900	Loss
STE_STE7_MEK1_MAP2K2_ST	P05787	KRT8	P36507	MAP2K2	S71	V77G	77	Missense	distal	6	no	2.947	2.821	EPSD	COSMIC	1.900	Down-regulation
STE_STE7_MEK1_MAP2K2_ST	P05787	KRT8	P36507	MAP2K2	S71	T64A	64	Missense	distal	-7	no	2.947	2.911	EPSD	COSMIC	1.900	Down-regulation
STE_STE7_MEK1_MAP2K2_ST	P05787	KRT8	P36507	MAP2K2	S74	S71R	71	Missense	distal	-3	no	8.868	8.972	PhosphoSitePlus	COSMIC	1.900	Up-regulation
STE_STE7_MEK1_MAP2K2_ST	P05787	KRT8	P36507	MAP2K2	S74	S71I	71	Missense	distal	-3	no	8.868	8.972	PhosphoSitePlus	COSMIC	1.900	Up-regulation
STE_STE7_MEK1_MAP2K2_ST	P05787	KRT8	P36507	MAP2K2	S74	V77G	77	Missense	distal	3	no	8.868	8.646	PhosphoSitePlus	COSMIC	1.900	Down-regulation
STE_STE7_MEK1_MAP2K2_ST	P05787	KRT8	P36507	MAP2K2	T131	T131M	131	Missense	central	0	yes	1.990	0.000	EPSD	COSMIC	1.900	Loss
STE_STE7_MEK1_MAP2K2_ST	P05787	KRT8	P36507	MAP2K2	S308	R301C	301	Missense	distal	-7	no	2.602	2.614	EPSD	COSMIC	1.900	Up-regulation
STE_STE7_MEK1_MAP2K2_ST	P05787	KRT8	P36507	MAP2K2	S308	M310I	310	Missense	proximal	2	no	2.602	2.558	EPSD	COSMIC	1.900	Down-regulation
STE_STE7_MEK1_MAP2K2_ST	P05787	KRT8	P36507	MAP2K2	S308	R302H	302	Missense	distal	-6	no	2.602	2.584	EPSD	COSMIC	1.900	Down-regulation
STE_STE7_MEK1_MAP2K2_ST	P05787	KRT8	P36507	MAP2K2	S308	E306G	306	Missense	proximal	-2	no	2.602	2.561	EPSD	COSMIC	1.900	Down-regulation
STE_STE7_MEK1_MAP2K2_ST	P05787	KRT8	P36507	MAP2K2	S308	R301Q	301	Missense	distal	-7	no	2.602	2.616	EPSD	COSMIC	1.900	Up-regulation
STE_STE7_MEK1_MAP2K2_ST	P05787	KRT8	P36507	MAP2K2	S450	S449F	449	Missense	proximal	-1	no	1.967	2.065	EPSD	COSMIC	1.900	Up-regulation
STE_STE7_MEK1_MAP2K2_ST	P05787	KRT8	P36507	MAP2K2	S450	S449A	449	Missense	proximal	-1	no	1.967	1.703	EPSD	COSMIC	1.900	Loss
STE_STE7_MEK1_MAP2K2_ST	P05787	KRT8	P36507	MAP2K2	S450	R454G	454	Missense	distal	4	no	1.967	2.103	EPSD	COSMIC	1.900	Up-regulation
STE_STE7_MEK1_MAP2K2_ST	P05787	KRT8	P36507	MAP2K2	S450	A447V	447	Missense	distal	-3	no	1.967	1.971	EPSD	COSMIC	1.900	Up-regulation
TK_Jak_JAK3_Y	O14939	PLD2	P52333	JAK3	Y415	S416I	416	Missense	proximal	1	no	105.166	102.897	PhosphoSitePlus	COSMIC	65.077	Down-regulation
TK_Jak_JAK3_Y	Q15910	EZH2	P52333	JAK3	Y244	L240P	240	Missense	distal	-4	no	87.814	87.354	PhosphoSitePlus	COSMIC	65.077	Down-regulation
TK_Jak_JAK3_Y	Q15910	EZH2	P52333	JAK3	Y244	Y244D	244	Missense	central	0	yes	87.814	0.000	PhosphoSitePlus	COSMIC	65.077	Loss
TK_Jak_JAK3_Y	Q15910	EZH2	P52333	JAK3	Y244	K243Q	243	Missense	proximal	-1	no	87.814	94.129	PhosphoSitePlus	COSMIC	65.077	Up-regulation
TK_Jak_JAK3_Y	Q15910	EZH2	P52333	JAK3	Y244	Q250K	250	Missense	distal	6	no	87.814	85.902	PhosphoSitePlus	COSMIC	65.077	Down-regulation
TK_Jak_JAK3_Y	O95644	NFATC1	P52333	JAK3	Y165	D167H	167	Missense	proximal	2	no	69.614	69.225	EPSD	COSMIC	65.077	Down-regulation
TK_Jak_JAK3_Y	O95644	NFATC1	P52333	JAK3	Y371	D365N	365	Missense	distal	-6	no	91.322	91.543	PhosphoSitePlus	COSMIC	65.077	Up-regulation
TK_Jak_JAK3_Y	O95644	NFATC1	P52333	JAK3	Y371	R378W	378	Missense	distal	7	no	91.322	90.404	PhosphoSitePlus	COSMIC	65.077	Down-regulation
TK_Jak_JAK3_Y	O95644	NFATC1	P52333	JAK3	Y371	A367G	367	Missense	distal	-4	no	91.322	90.851	PhosphoSitePlus	COSMIC	65.077	Down-regulation
TK_Jak_JAK3_Y	O95644	NFATC1	P52333	JAK3	Y371	E369K	369	Missense	proximal	-2	no	91.322	91.435	PhosphoSitePlus	COSMIC;CCLE	65.077	Up-regulation
TK_Jak_JAK3_Y	O95644	NFATC1	P52333	JAK3	Y371	S373C	373	Missense	proximal	2	no	91.322	88.356	PhosphoSitePlus	COSMIC	65.077	Down-regulation
TK_Jak_JAK3_Y	P52333	JAK3	P52333	JAK3	Y506	Q501H	501	Missense	distal	-5	no	88.067	89.939	EPSD	COSMIC;CCLE	65.077	Up-regulation
TK_Jak_JAK3_Y	P52333	JAK3	P52333	JAK3	Y506	L499F	499	Missense	distal	-7	no	88.067	79.577	EPSD	COSMIC	65.077	Down-regulation
TK_Jak_JAK3_Y	P52333	JAK3	P52333	JAK3	Y506	Q510R	510	Missense	distal	4	no	88.067	83.714	EPSD	COSMIC;GDSC;CCLE	65.077	Down-regulation
TK_Jak_JAK3_Y	P52333	JAK3	P52333	JAK3	Y506	Q507P	507	Missense	proximal	1	no	88.067	85.723	EPSD	COSMIC	65.077	Down-regulation
TK_Jak_JAK3_Y	P52333	JAK3	P52333	JAK3	Y506	F513I	513	Missense	distal	7	no	88.067	88.142	EPSD	COSMIC	65.077	Up-regulation
TK_Jak_JAK3_Y	P52333	JAK3	P52333	JAK3	Y506	Q503H	503	Missense	distal	-3	no	88.067	85.358	EPSD	COSMIC	65.077	Down-regulation
TK_Jak_JAK3_Y	P52333	JAK3	P52333	JAK3	Y785	P791R	791	Missense	distal	6	no	111.759	111.810	PhosphoSitePlus;EPSD	COSMIC	65.077	Up-regulation
TK_Jak_JAK3_Y	P52333	JAK3	P52333	JAK3	Y785	N778S	778	Missense	distal	-7	no	111.759	124.357	PhosphoSitePlus;EPSD	COSMIC	65.077	Up-regulation
TK_Jak_JAK3_Y	P52333	JAK3	P52333	JAK3	Y785	S789A	789	Missense	distal	4	no	111.759	108.798	PhosphoSitePlus;EPSD	COSMIC	65.077	Down-regulation
TK_Jak_JAK3_Y	P52333	JAK3	P52333	JAK3	Y785	L788F	788	Missense	distal	3	no	111.759	108.709	PhosphoSitePlus;EPSD	COSMIC	65.077	Down-regulation
TK_Jak_JAK3_Y	P52333	JAK3	P52333	JAK3	Y785	I781M	781	Missense	distal	-4	no	111.759	111.874	PhosphoSitePlus;EPSD	COSMIC	65.077	Up-regulation
TK_Jak_JAK3_Y	P52333	JAK3	P52333	JAK3	Y785	S789P	789	Missense	distal	4	no	111.759	95.212	PhosphoSitePlus;EPSD	COSMIC	65.077	Down-regulation
TK_Jak_JAK3_Y	P52333	JAK3	P52333	JAK3	Y904	L910S	910	Missense	distal	6	no	108.604	106.213	EPSD;PhosphoSitePlus	COSMIC	65.077	Down-regulation
TK_Jak_JAK3_Y	P52333	JAK3	P52333	JAK3	Y904	P906L	906	Missense	proximal	2	no	108.604	109.222	EPSD;PhosphoSitePlus	COSMIC	65.077	Up-regulation
TK_Jak_JAK3_Y	P52333	JAK3	P52333	JAK3	Y939	Q932H	932	Missense	distal	-7	no	106.715	105.243	EPSD;PhosphoSitePlus	COSMIC	65.077	Down-regulation
TK_Jak_JAK3_Y	P52333	JAK3	P52333	JAK3	Y939	Y939S	939	Missense	central	0	yes	106.715	0.000	EPSD;PhosphoSitePlus	COSMIC	65.077	Loss
TK_Jak_JAK3_Y	P52333	JAK3	P52333	JAK3	Y939	R944H	944	Missense	distal	5	no	106.715	107.782	EPSD;PhosphoSitePlus	COSMIC	65.077	Up-regulation
TK_Jak_JAK3_Y	P52333	JAK3	P52333	JAK3	Y980	L976R	976	Missense	distal	-4	no	109.461	109.054	EPSD;PhosphoSitePlus	COSMIC	65.077	Down-regulation
TK_Jak_JAK3_Y	P52333	JAK3	P52333	JAK3	Y980	P986S	986	Missense	distal	6	no	109.461	107.223	EPSD;PhosphoSitePlus	COSMIC	65.077	Down-regulation
TK_Jak_JAK3_Y	P52333	JAK3	P52333	JAK3	Y980	R984C	984	Missense	distal	4	no	109.461	82.079	EPSD;PhosphoSitePlus	COSMIC	65.077	Down-regulation
TK_Jak_JAK3_Y	P52333	JAK3	P52333	JAK3	Y980	Y980N	980	Missense	central	0	yes	109.461	0.000	EPSD;PhosphoSitePlus	COSMIC	65.077	Loss
TK_Jak_JAK3_Y	P52333	JAK3	P52333	JAK3	Y980	R984H	984	Missense	distal	4	no	109.461	97.064	EPSD;PhosphoSitePlus	COSMIC	65.077	Down-regulation
TK_Jak_JAK3_Y	P52333	JAK3	P52333	JAK3	Y980	D979N	979	Missense	proximal	-1	no	109.461	99.716	EPSD;PhosphoSitePlus	COSMIC	65.077	Down-regulation
TK_Jak_JAK3_Y	P52333	JAK3	P52333	JAK3	Y980	G987C	987	Missense	distal	7	no	109.461	107.173	EPSD;PhosphoSitePlus	COSMIC;CCLE	65.077	Down-regulation
TK_Jak_JAK3_Y	P52333	JAK3	P52333	JAK3	Y981	L976R	976	Missense	distal	-5	no	114.399	112.439	EPSD;PhosphoSitePlus	COSMIC	65.077	Down-regulation
TK_Jak_JAK3_Y	P52333	JAK3	P52333	JAK3	Y981	P986S	986	Missense	distal	5	no	114.399	112.588	EPSD;PhosphoSitePlus	COSMIC	65.077	Down-regulation
TK_Jak_JAK3_Y	P52333	JAK3	P52333	JAK3	Y981	R984C	984	Missense	distal	3	no	114.399	108.555	EPSD;PhosphoSitePlus	COSMIC	65.077	Down-regulation
TK_Jak_JAK3_Y	P52333	JAK3	P52333	JAK3	Y981	Y980N	980	Missense	proximal	-1	no	114.399	118.314	EPSD;PhosphoSitePlus	COSMIC	65.077	Up-regulation
TK_Jak_JAK3_Y	P52333	JAK3	P52333	JAK3	Y981	R984H	984	Missense	distal	3	no	114.399	113.940	EPSD;PhosphoSitePlus	COSMIC	65.077	Down-regulation
TK_Jak_JAK3_Y	P52333	JAK3	P52333	JAK3	Y981	D979N	979	Missense	proximal	-2	no	114.399	113.412	EPSD;PhosphoSitePlus	COSMIC	65.077	Down-regulation
TK_Jak_JAK3_Y	P52333	JAK3	P52333	JAK3	Y981	G987C	987	Missense	distal	6	no	114.399	117.975	EPSD;PhosphoSitePlus	COSMIC;CCLE	65.077	Up-regulation
TK_Jak_JAK3_Y	P52333	JAK3	P52333	JAK3	Y981	Q988P	988	Missense	distal	7	no	114.399	114.226	EPSD;PhosphoSitePlus	COSMIC	65.077	Down-regulation
TK_Jak_JAK3_Y	P42229	STAT5A	P52333	JAK3	Y694	A688D	688	Missense	distal	-6	no	107.279	107.638	PhosphoSitePlus	COSMIC	65.077	Up-regulation
TK_Jak_JAK3_Y	P23458	JAK1	P52333	JAK3	Y993	R997Q	997	Missense	distal	4	no	113.858	118.211	EPSD	COSMIC	65.077	Up-regulation
TK_Jak_JAK3_Y	P23458	JAK1	P52333	JAK3	Y993	G990R	990	Missense	distal	-3	no	113.858	110.578	EPSD	COSMIC	65.077	Down-regulation
TK_Jak_JAK3_Y	P23458	JAK1	P52333	JAK3	Y993	S996F	996	Missense	distal	3	no	113.858	107.258	EPSD	COSMIC	65.077	Down-regulation
TK_Jak_JAK3_Y	P23458	JAK1	P52333	JAK3	Y1034	E1029K	1029	Missense	distal	-5	no	121.690	121.892	PhosphoSitePlus;EPSD	COSMIC	65.077	Up-regulation
TK_Jak_JAK3_Y	P23458	JAK1	P52333	JAK3	Y1034	K1032T	1032	Missense	proximal	-2	no	121.690	121.021	PhosphoSitePlus;EPSD	COSMIC	65.077	Down-regulation
TK_Jak_JAK3_Y	P23458	JAK1	P52333	JAK3	Y1035	E1029K	1029	Missense	distal	-6	no	109.428	109.238	EPSD;PhosphoSitePlus	COSMIC	65.077	Down-regulation
TK_Jak_JAK3_Y	P23458	JAK1	P52333	JAK3	Y1035	K1032T	1032	Missense	distal	-3	no	109.428	108.852	EPSD;PhosphoSitePlus	COSMIC	65.077	Down-regulation
TK_Jak_JAK3_Y	Q96LC7	SIGLEC10	P52333	JAK3	Y597	T593M	593	Missense	distal	-4	no	72.626	72.906	EPSD;PhosphoSitePlus	COSMIC	65.077	Up-regulation
TK_Jak_JAK3_Y	Q96LC7	SIGLEC10	P52333	JAK3	Y597	R590Q	590	Missense	distal	-7	no	72.626	72.395	EPSD;PhosphoSitePlus	COSMIC	65.077	Down-regulation
TK_Jak_JAK3_Y	Q96LC7	SIGLEC10	P52333	JAK3	Y597	I598N	598	Missense	proximal	1	no	72.626	68.489	EPSD;PhosphoSitePlus	COSMIC	65.077	Down-regulation
TK_Jak_JAK3_Y	Q96LC7	SIGLEC10	P52333	JAK3	Y597	N599K	599	Missense	proximal	2	no	72.626	73.425	EPSD;PhosphoSitePlus	COSMIC	65.077	Up-regulation
TK_Jak_JAK3_Y	Q96LC7	SIGLEC10	P52333	JAK3	Y597	Y597C	597	Missense	central	0	yes	72.626	0.000	EPSD;PhosphoSitePlus	COSMIC	65.077	Loss
TK_Jak_JAK3_Y	Q96LC7	SIGLEC10	P52333	JAK3	Y641	K638T	638	Missense	distal	-3	no	85.795	85.219	EPSD	COSMIC	65.077	Down-regulation
TK_Jak_JAK3_Y	Q96LC7	SIGLEC10	P52333	JAK3	Y667	S661I	661	Missense	distal	-6	no	93.502	94.011	PhosphoSitePlus;EPSD	COSMIC	65.077	Up-regulation
TK_Jak_JAK3_Y	Q96LC7	SIGLEC10	P52333	JAK3	Y691	G686D	686	Missense	distal	-5	no	77.155	77.101	EPSD;PhosphoSitePlus	COSMIC	65.077	Down-regulation
TK_Jak_JAK3_Y	Q96LC7	SIGLEC10	P52333	JAK3	Y691	Q688R	688	Missense	distal	-3	no	77.155	75.010	EPSD;PhosphoSitePlus	COSMIC	65.077	Down-regulation
TK_Jak_JAK3_Y	Q96LC7	SIGLEC10	P52333	JAK3	Y691	Q688H	688	Missense	distal	-3	no	77.155	74.446	EPSD;PhosphoSitePlus	COSMIC	65.077	Down-regulation
TK_Jak_JAK3_Y	P29353	SHC1	P52333	JAK3	Y558	P565S	565	Missense	distal	7	no	100.628	101.634	EPSD	COSMIC	65.077	Up-regulation
TK_Jak_JAK3_Y	P35222	CTNNB1	P52333	JAK3	Y30	I35T	35	Missense	distal	5	no	109.963	110.118	EPSD;PhosphoSitePlus	COSMIC	65.077	Up-regulation
TK_Jak_JAK3_Y	P35222	CTNNB1	P52333	JAK3	Y30	Q28E	28	Missense	proximal	-2	no	109.963	110.506	EPSD;PhosphoSitePlus	COSMIC	65.077	Up-regulation
TK_Jak_JAK3_Y	P35222	CTNNB1	P52333	JAK3	Y30	D32E	32	Missense	proximal	2	no	109.963	110.728	EPSD;PhosphoSitePlus	COSMIC	65.077	Up-regulation
TK_Jak_JAK3_Y	P35222	CTNNB1	P52333	JAK3	Y30	H36R	36	Missense	distal	6	no	109.963	109.452	EPSD;PhosphoSitePlus	COSMIC	65.077	Down-regulation
TK_Jak_JAK3_Y	P35222	CTNNB1	P52333	JAK3	Y30	G34L	34	Missense	distal	4	no	109.963	88.496	EPSD;PhosphoSitePlus	COSMIC	65.077	Down-regulation
TK_Jak_JAK3_Y	P35222	CTNNB1	P52333	JAK3	Y30	S33L	33	Missense	distal	3	no	109.963	106.412	EPSD;PhosphoSitePlus	COSMIC;CCLE	65.077	Down-regulation
TK_Jak_JAK3_Y	P35222	CTNNB1	P52333	JAK3	Y30	S29P	29	Missense	proximal	-1	no	109.963	102.675	EPSD;PhosphoSitePlus	COSMIC	65.077	Down-regulation
TK_Jak_JAK3_Y	P35222	CTNNB1	P52333	JAK3	Y30	L31P	31	Missense	proximal	1	no	109.963	103.796	EPSD;PhosphoSitePlus	COSMIC	65.077	Down-regulation
TK_Jak_JAK3_Y	P35222	CTNNB1	P52333	JAK3	Y30	S37L	37	Missense	distal	7	no	109.963	108.524	EPSD;PhosphoSitePlus	COSMIC	65.077	Down-regulation
TK_Jak_JAK3_Y	P35222	CTNNB1	P52333	JAK3	Y30	Q27H	27	Missense	distal	-3	no	109.963	107.255	EPSD;PhosphoSitePlus	COSMIC	65.077	Down-regulation
TK_Jak_JAK3_Y	P35222	CTNNB1	P52333	JAK3	Y30	S33N	33	Missense	distal	3	no	109.963	102.575	EPSD;PhosphoSitePlus	COSMIC	65.077	Down-regulation
TK_Jak_JAK3_Y	P35222	CTNNB1	P52333	JAK3	Y30	H36Y	36	Missense	distal	6	no	109.963	110.046	EPSD;PhosphoSitePlus	COSMIC	65.077	Up-regulation
TK_Jak_JAK3_Y	P35222	CTNNB1	P52333	JAK3	Y30	S23N	23	Missense	distal	-7	no	109.963	97.365	EPSD;PhosphoSitePlus	COSMIC	65.077	Down-regulation
TK_Jak_JAK3_Y	P35222	CTNNB1	P52333	JAK3	Y30	S29F	29	Missense	proximal	-1	no	109.963	101.831	EPSD;PhosphoSitePlus	COSMIC	65.077	Down-regulation
TK_Jak_JAK3_Y	P35222	CTNNB1	P52333	JAK3	Y30	Y30C	30	Missense	central	0	yes	109.963	0.000	EPSD;PhosphoSitePlus	COSMIC	65.077	Loss
TK_Jak_JAK3_Y	P35222	CTNNB1	P52333	JAK3	Y30	S29Y	29	Missense	proximal	-1	no	109.963	103.291	EPSD;PhosphoSitePlus	COSMIC	65.077	Down-regulation
TK_Jak_JAK3_Y	P35222	CTNNB1	P52333	JAK3	Y30	S23R	23	Missense	distal	-7	no	109.963	101.800	EPSD;PhosphoSitePlus	COSMIC	65.077	Down-regulation
TK_Jak_JAK3_Y	P35222	CTNNB1	P52333	JAK3	Y30	H24Y	24	Missense	distal	-6	no	109.963	109.803	EPSD;PhosphoSitePlus	COSMIC	65.077	Down-regulation
TK_Jak_JAK3_Y	P35222	CTNNB1	P52333	JAK3	Y30	W25R	25	Missense	distal	-5	no	109.963	107.571	EPSD;PhosphoSitePlus	COSMIC	65.077	Down-regulation
TK_Jak_JAK3_Y	P35222	CTNNB1	P52333	JAK3	Y30	I35M	35	Missense	distal	5	no	109.963	108.893	EPSD;PhosphoSitePlus	COSMIC	65.077	Down-regulation
TK_Jak_JAK3_Y	P35222	CTNNB1	P52333	JAK3	Y30	W25L	25	Missense	distal	-5	no	109.963	109.532	EPSD;PhosphoSitePlus	COSMIC	65.077	Down-regulation
TK_Jak_JAK3_Y	P35222	CTNNB1	P52333	JAK3	Y30	H24Q	24	Missense	distal	-6	no	109.963	109.443	EPSD;PhosphoSitePlus	COSMIC	65.077	Down-regulation
TK_Jak_JAK3_Y	P35222	CTNNB1	P52333	JAK3	Y30	S23G	23	Missense	distal	-7	no	109.963	93.351	EPSD;PhosphoSitePlus	COSMIC	65.077	Down-regulation
TK_Jak_JAK3_Y	P35222	CTNNB1	P52333	JAK3	Y30	S29A	29	Missense	proximal	-1	no	109.963	100.183	EPSD;PhosphoSitePlus	COSMIC	65.077	Down-regulation
TK_Jak_JAK3_Y	P35222	CTNNB1	P52333	JAK3	Y30	G34A	34	Missense	distal	4	no	109.963	108.358	EPSD;PhosphoSitePlus	COSMIC	65.077	Down-regulation
TK_Jak_JAK3_Y	P35222	CTNNB1	P52333	JAK3	Y30	L31W	31	Missense	proximal	1	no	109.963	104.157	EPSD;PhosphoSitePlus	COSMIC	65.077	Down-regulation
TK_Jak_JAK3_Y	P35222	CTNNB1	P52333	JAK3	Y30	G34I	34	Missense	distal	4	no	109.963	94.201	EPSD;PhosphoSitePlus	COSMIC	65.077	Down-regulation
TK_Jak_JAK3_Y	P35222	CTNNB1	P52333	JAK3	Y30	I35N	35	Missense	distal	5	no	109.963	111.067	EPSD;PhosphoSitePlus	COSMIC	65.077	Up-regulation
TK_Jak_JAK3_Y	P35222	CTNNB1	P52333	JAK3	Y30	D32C	32	Missense	proximal	2	no	109.963	108.374	EPSD;PhosphoSitePlus	COSMIC	65.077	Down-regulation
TK_Jak_JAK3_Y	P35222	CTNNB1	P52333	JAK3	Y30	Y30S	30	Missense	central	0	yes	109.963	0.000	EPSD;PhosphoSitePlus	COSMIC	65.077	Loss
TK_Jak_JAK3_Y	P35222	CTNNB1	P52333	JAK3	Y30	L31M	31	Missense	proximal	1	no	109.963	107.762	EPSD;PhosphoSitePlus	COSMIC	65.077	Down-regulation
TK_Jak_JAK3_Y	P35222	CTNNB1	P52333	JAK3	Y30	H24R	24	Missense	distal	-6	no	109.963	109.522	EPSD;PhosphoSitePlus	COSMIC	65.077	Down-regulation
TK_Jak_JAK3_Y	P35222	CTNNB1	P52333	JAK3	Y30	L31Q	31	Missense	proximal	1	no	109.963	106.140	EPSD;PhosphoSitePlus	COSMIC	65.077	Down-regulation
TK_Jak_JAK3_Y	P35222	CTNNB1	P52333	JAK3	Y30	G34D	34	Missense	distal	4	no	109.963	107.705	EPSD;PhosphoSitePlus	COSMIC	65.077	Down-regulation
TK_Jak_JAK3_Y	P35222	CTNNB1	P52333	JAK3	Y30	Q26R	26	Missense	distal	-4	no	109.963	109.865	EPSD;PhosphoSitePlus	COSMIC;GDSC;CCLE	65.077	Down-regulation
TK_Jak_JAK3_Y	P35222	CTNNB1	P52333	JAK3	Y30	S37T	37	Missense	distal	7	no	109.963	109.219	EPSD;PhosphoSitePlus	COSMIC	65.077	Down-regulation
TK_Jak_JAK3_Y	P35222	CTNNB1	P52333	JAK3	Y30	I35K	35	Missense	distal	5	no	109.963	107.477	EPSD;PhosphoSitePlus	COSMIC	65.077	Down-regulation
TK_Jak_JAK3_Y	P35222	CTNNB1	P52333	JAK3	Y30	Q28R	28	Missense	proximal	-2	no	109.963	108.899	EPSD;PhosphoSitePlus	COSMIC	65.077	Down-regulation
TK_Jak_JAK3_Y	P35222	CTNNB1	P52333	JAK3	Y30	D32F	32	Missense	proximal	2	no	109.963	109.571	EPSD;PhosphoSitePlus	COSMIC	65.077	Down-regulation
TK_Jak_JAK3_Y	P35222	CTNNB1	P52333	JAK3	Y30	D32X	32	Missense	proximal	2	no	109.963	109.689	EPSD;PhosphoSitePlus	COSMIC	65.077	Down-regulation
TK_Jak_JAK3_Y	P35222	CTNNB1	P52333	JAK3	Y30	S33K	33	Missense	distal	3	no	109.963	106.152	EPSD;PhosphoSitePlus	COSMIC	65.077	Down-regulation
TK_Jak_JAK3_Y	P35222	CTNNB1	P52333	JAK3	Y30	I35V	35	Missense	distal	5	no	109.963	108.248	EPSD;PhosphoSitePlus	COSMIC	65.077	Down-regulation
TK_Jak_JAK3_Y	P35222	CTNNB1	P52333	JAK3	Y30	S29T	29	Missense	proximal	-1	no	109.963	104.041	EPSD;PhosphoSitePlus	COSMIC	65.077	Down-regulation
TK_Jak_JAK3_Y	P35222	CTNNB1	P52333	JAK3	Y30	G34C	34	Missense	distal	4	no	109.963	81.148	EPSD;PhosphoSitePlus	COSMIC	65.077	Down-regulation
TK_Jak_JAK3_Y	P35222	CTNNB1	P52333	JAK3	Y30	S37V	37	Missense	distal	7	no	109.963	109.668	EPSD;PhosphoSitePlus	COSMIC	65.077	Down-regulation
TK_Jak_JAK3_Y	P35222	CTNNB1	P52333	JAK3	Y30	I35F	35	Missense	distal	5	no	109.963	110.060	EPSD;PhosphoSitePlus	COSMIC	65.077	Up-regulation
TK_Jak_JAK3_Y	P35222	CTNNB1	P52333	JAK3	Y64	V62G	62	Missense	proximal	-2	no	100.828	99.372	EPSD;PhosphoSitePlus	COSMIC	65.077	Down-regulation
TK_Jak_JAK3_Y	P35222	CTNNB1	P52333	JAK3	Y64	Q61R	61	Missense	distal	-3	no	100.828	98.683	EPSD;PhosphoSitePlus	COSMIC	65.077	Down-regulation
TK_Jak_JAK3_Y	P35222	CTNNB1	P52333	JAK3	Y64	D58N	58	Missense	distal	-6	no	100.828	101.049	EPSD;PhosphoSitePlus	COSMIC	65.077	Up-regulation
TK_Jak_JAK3_Y	P35222	CTNNB1	P52333	JAK3	Y64	V57A	57	Missense	distal	-7	no	100.828	94.111	EPSD;PhosphoSitePlus	COSMIC	65.077	Down-regulation
TK_Jak_JAK3_Y	P35222	CTNNB1	P52333	JAK3	Y64	S60C	60	Missense	distal	-4	no	100.828	98.733	EPSD;PhosphoSitePlus	COSMIC	65.077	Down-regulation
TK_Jak_JAK3_Y	P35222	CTNNB1	P52333	JAK3	Y64	V57M	57	Missense	distal	-7	no	100.828	88.144	EPSD;PhosphoSitePlus	COSMIC	65.077	Down-regulation
TK_Jak_JAK3_Y	P35222	CTNNB1	P52333	JAK3	Y64	G69E	69	Missense	distal	5	no	100.828	99.575	EPSD;PhosphoSitePlus	COSMIC	65.077	Down-regulation
TK_Jak_JAK3_Y	P35222	CTNNB1	P52333	JAK3	Y64	Q61L	61	Missense	distal	-3	no	100.828	98.047	EPSD;PhosphoSitePlus	COSMIC	65.077	Down-regulation
TK_Jak_JAK3_Y	P35222	CTNNB1	P52333	JAK3	Y64	E67K	67	Missense	distal	3	no	100.828	100.093	EPSD;PhosphoSitePlus	COSMIC	65.077	Down-regulation
TK_Jak_JAK3_Y	P35222	CTNNB1	P52333	JAK3	Y64	W66L	66	Missense	proximal	2	no	100.828	101.702	EPSD;PhosphoSitePlus	COSMIC	65.077	Up-regulation
TK_Jak_JAK3_Y	P35222	CTNNB1	P52333	JAK3	Y64	E65K	65	Missense	proximal	1	no	100.828	101.789	EPSD;PhosphoSitePlus	COSMIC	65.077	Up-regulation
TK_Jak_JAK3_Y	P35222	CTNNB1	P52333	JAK3	Y64	G69A	69	Missense	distal	5	no	100.828	101.481	EPSD;PhosphoSitePlus	COSMIC	65.077	Up-regulation
TK_Jak_JAK3_Y	P35222	CTNNB1	P52333	JAK3	Y64	E67N	67	Missense	distal	3	no	100.828	96.516	EPSD;PhosphoSitePlus	COSMIC	65.077	Down-regulation
TK_Jak_JAK3_Y	P35222	CTNNB1	P52333	JAK3	Y64	L63M	63	Missense	proximal	-1	no	100.828	110.177	EPSD;PhosphoSitePlus	COSMIC	65.077	Up-regulation
TK_Jak_JAK3_Y	P35222	CTNNB1	P52333	JAK3	Y64	T59A	59	Missense	distal	-5	no	100.828	100.364	EPSD;PhosphoSitePlus	COSMIC	65.077	Down-regulation
TK_Jak_JAK3_Y	P35222	CTNNB1	P52333	JAK3	Y86	Y86H	86	Missense	central	0	yes	110.336	0.000	PhosphoSitePlus;EPSD	COSMIC	65.077	Loss
TK_Jak_JAK3_Y	P35222	CTNNB1	P52333	JAK3	Y86	V79I	79	Missense	distal	-7	no	110.336	100.681	PhosphoSitePlus;EPSD	COSMIC	65.077	Down-regulation
TK_Jak_JAK3_Y	P35222	CTNNB1	P52333	JAK3	Y86	R93S	93	Missense	distal	7	no	110.336	111.268	PhosphoSitePlus;EPSD	COSMIC	65.077	Up-regulation
TK_Jak_JAK3_Y	P35222	CTNNB1	P52333	JAK3	Y86	D83N	83	Missense	distal	-3	no	110.336	109.004	PhosphoSitePlus;EPSD	COSMIC	65.077	Down-regulation
TK_Jak_JAK3_Y	P35222	CTNNB1	P52333	JAK3	Y86	I82F	82	Missense	distal	-4	no	110.336	109.784	PhosphoSitePlus;EPSD	COSMIC	65.077	Down-regulation
TK_Jak_JAK3_Y	P35222	CTNNB1	P52333	JAK3	Y86	M88V	88	Missense	proximal	2	no	110.336	111.031	PhosphoSitePlus;EPSD	COSMIC	65.077	Up-regulation
TK_Jak_JAK3_Y	P35222	CTNNB1	P52333	JAK3	Y86	I82V	82	Missense	distal	-4	no	110.336	111.546	PhosphoSitePlus;EPSD	COSMIC	65.077	Up-regulation
TK_Jak_JAK3_Y	P35222	CTNNB1	P52333	JAK3	Y331	V325I	325	Missense	distal	-6	no	69.894	70.696	EPSD	COSMIC	65.077	Up-regulation
TK_Jak_JAK3_Y	P35222	CTNNB1	P52333	JAK3	Y331	L336V	336	Missense	distal	5	no	69.894	68.451	EPSD	COSMIC	65.077	Down-regulation
TK_Jak_JAK3_Y	P35222	CTNNB1	P52333	JAK3	Y331	I327T	327	Missense	distal	-4	no	69.894	69.729	EPSD	COSMIC	65.077	Down-regulation
TK_Jak_JAK3_Y	P35222	CTNNB1	P52333	JAK3	Y331	I327V	327	Missense	distal	-4	no	69.894	71.104	EPSD	COSMIC	65.077	Up-regulation
TK_Jak_JAK3_Y	P35222	CTNNB1	P52333	JAK3	Y331	K335R	335	Missense	distal	4	no	69.894	62.681	EPSD	COSMIC	65.077	Loss
TK_Jak_JAK3_Y	P35222	CTNNB1	P52333	JAK3	Y331	K335Q	335	Missense	distal	4	no	69.894	67.033	EPSD	COSMIC	65.077	Down-regulation
TK_Jak_JAK3_Y	P35222	CTNNB1	P52333	JAK3	Y331	L337P	337	Missense	distal	6	no	69.894	69.741	EPSD	COSMIC	65.077	Down-regulation
TK_Jak_JAK3_Y	P35222	CTNNB1	P52333	JAK3	Y331	L324H	324	Missense	distal	-7	no	69.894	62.654	EPSD	COSMIC	65.077	Loss
TK_Jak_JAK3_Y	Q15717	ELAVL1	P52333	JAK3	Y63	Y68C	68	Missense	distal	5	no	110.612	114.638	PhosphoSitePlus;EPSD	COSMIC	65.077	Up-regulation
TK_Jak_JAK3_Y	Q15717	ELAVL1	P52333	JAK3	Y68	Y68C	68	Missense	central	0	yes	99.871	0.000	EPSD;PhosphoSitePlus	COSMIC	65.077	Loss
TK_Jak_JAK3_Y	Q15717	ELAVL1	P52333	JAK3	Y200	R206W	206	Missense	distal	6	no	104.116	105.663	EPSD;PhosphoSitePlus	COSMIC	65.077	Up-regulation
TK_Jak_JAK3_Y	Q15717	ELAVL1	P52333	JAK3	Y200	L195F	195	Missense	distal	-5	no	104.116	101.509	EPSD;PhosphoSitePlus	COSMIC	65.077	Down-regulation
TK_Jak_JAK3_Y	P42224	STAT1	P52333	JAK3	Y701	D694N	694	Missense	distal	-7	no	110.959	111.402	PhosphoSitePlus	COSMIC	65.077	Up-regulation
TK_Jak_JAK3_Y	P42224	STAT1	P52333	JAK3	Y701	K697I	697	Missense	distal	-4	no	110.959	110.816	PhosphoSitePlus	COSMIC	65.077	Down-regulation
TK_Tec_ITK_Y	Q06187	BTK	Q08881	ITK	Y223	L222F	222	Missense	proximal	-1	no	18.601	18.931	PhosphoSitePlus	COSMIC	9.294	Up-regulation
TK_Tec_ITK_Y	Q06187	BTK	Q08881	ITK	Y223	D224N	224	Missense	proximal	1	no	18.601	18.728	PhosphoSitePlus	COSMIC	9.294	Up-regulation
TK_Tec_ITK_Y	Q06187	BTK	Q08881	ITK	Y223	K217R	217	Missense	distal	-6	no	18.601	18.851	PhosphoSitePlus	COSMIC	9.294	Up-regulation
TK_Tec_ITK_Y	Q06187	BTK	Q08881	ITK	Y225	L222F	222	Missense	distal	-3	no	12.025	12.303	EPSD	COSMIC	9.294	Up-regulation
TK_Tec_ITK_Y	Q06187	BTK	Q08881	ITK	Y225	D224N	224	Missense	proximal	-1	no	12.025	11.903	EPSD	COSMIC	9.294	Down-regulation
TK_Tec_ITK_Y	Q08881	ITK	Q08881	ITK	Y180	E173A	173	Missense	distal	-7	no	18.295	18.602	PhosphoSitePlus	COSMIC	9.294	Up-regulation
TK_Tec_ITK_Y	Q08881	ITK	Q08881	ITK	Y180	P187S	187	Missense	distal	7	no	18.295	18.372	PhosphoSitePlus	COSMIC	9.294	Up-regulation
TK_Tec_ITK_Y	Q08881	ITK	Q08881	ITK	Y182	P187S	187	Missense	distal	5	no	9.788	8.419	EPSD	COSMIC	9.294	Loss
TK_Tec_ITK_Y	Q08881	ITK	Q08881	ITK	Y182	Q188R	188	Missense	distal	6	no	9.788	10.099	EPSD	COSMIC;GDSC;CCLE	9.294	Up-regulation
TK_Tec_ITK_Y	Q9H4E7	DEF6	Q08881	ITK	Y222	L229P	229	Missense	distal	7	no	19.489	19.345	PhosphoSitePlus;EPSD	COSMIC	9.294	Down-regulation
TK_Tec_ITK_Y	Q9H4E7	DEF6	Q08881	ITK	Y222	G227E	227	Missense	distal	5	no	19.489	19.738	PhosphoSitePlus;EPSD	COSMIC	9.294	Up-regulation
TK_Tec_ITK_Y	P19174	PLCG1	Q08881	ITK	Y93	F99L	99	Missense	distal	6	no	12.748	12.652	EPSD	COSMIC	9.294	Down-regulation
TK_Tec_ITK_Y	P19174	PLCG1	Q08881	ITK	Y93	R88W	88	Missense	distal	-5	no	12.748	11.291	EPSD	COSMIC	9.294	Down-regulation
TK_Tec_ITK_Y	P19174	PLCG1	Q08881	ITK	Y775	Y775F	775	Missense	central	0	yes	10.668	0.000	EPSD	COSMIC	9.294	Loss
TK_Tec_ITK_Y	P19174	PLCG1	Q08881	ITK	Y991	A995P	995	Missense	distal	4	no	9.580	9.743	EPSD	COSMIC;GDSC;CCLE	9.294	Up-regulation
TK_Tec_ITK_Y	P19174	PLCG1	Q08881	ITK	Y991	G997S	997	Missense	distal	6	no	9.580	9.586	EPSD	COSMIC	9.294	Up-regulation
TK_Tec_ITK_Y	P19174	PLCG1	Q08881	ITK	Y991	P984L	984	Missense	distal	-7	no	9.580	8.768	EPSD	COSMIC	9.294	Loss
TK_Tec_ITK_Y	P51813	BMX	Q08881	ITK	Y216	T211P	211	Missense	distal	-5	no	20.962	20.731	PhosphoSitePlus	COSMIC	9.294	Down-regulation
TK_Tec_ITK_Y	P51813	BMX	Q08881	ITK	Y216	S220L	220	Missense	distal	4	no	20.962	20.460	PhosphoSitePlus	COSMIC	9.294	Down-regulation
TK_Tec_ITK_Y	Q96LC7	SIGLEC10	Q08881	ITK	Y597	T593M	593	Missense	distal	-4	no	20.710	20.668	EPSD;PhosphoSitePlus	COSMIC	9.294	Down-regulation
TK_Tec_ITK_Y	Q96LC7	SIGLEC10	Q08881	ITK	Y597	R590Q	590	Missense	distal	-7	no	20.710	20.219	EPSD;PhosphoSitePlus	COSMIC	9.294	Down-regulation
TK_Tec_ITK_Y	Q96LC7	SIGLEC10	Q08881	ITK	Y597	I598N	598	Missense	proximal	1	no	20.710	20.526	EPSD;PhosphoSitePlus	COSMIC	9.294	Down-regulation
TK_Tec_ITK_Y	Q96LC7	SIGLEC10	Q08881	ITK	Y597	N599K	599	Missense	proximal	2	no	20.710	20.593	EPSD;PhosphoSitePlus	COSMIC	9.294	Down-regulation
TK_Tec_ITK_Y	Q96LC7	SIGLEC10	Q08881	ITK	Y597	Y597C	597	Missense	central	0	yes	20.710	0.000	EPSD;PhosphoSitePlus	COSMIC	9.294	Loss
TK_Tec_ITK_Y	Q96LC7	SIGLEC10	Q08881	ITK	Y641	K638T	638	Missense	distal	-3	no	9.591	9.329	EPSD	COSMIC	9.294	Down-regulation
TK_Tec_ITK_Y	Q96LC7	SIGLEC10	Q08881	ITK	Y667	S661I	661	Missense	distal	-6	no	18.530	18.275	PhosphoSitePlus;EPSD	COSMIC	9.294	Down-regulation
TK_Tec_ITK_Y	Q96LC7	SIGLEC10	Q08881	ITK	Y691	G686D	686	Missense	distal	-5	no	12.973	12.502	EPSD	COSMIC	9.294	Down-regulation
TK_Tec_ITK_Y	Q96LC7	SIGLEC10	Q08881	ITK	Y691	Q688R	688	Missense	distal	-3	no	12.973	12.922	EPSD	COSMIC	9.294	Down-regulation
TK_Tec_ITK_Y	Q96LC7	SIGLEC10	Q08881	ITK	Y691	Q688H	688	Missense	distal	-3	no	12.973	13.634	EPSD	COSMIC	9.294	Up-regulation
TK_Tec_ITK_Y	Q8TDQ0	HAVCR2	Q08881	ITK	Y265	R259M	259	Missense	distal	-6	no	20.501	20.161	PhosphoSitePlus	COSMIC	9.294	Down-regulation
TK_Tec_ITK_Y	Q8TDQ0	HAVCR2	Q08881	ITK	Y265	R259S	259	Missense	distal	-6	no	20.501	20.416	PhosphoSitePlus	COSMIC	9.294	Down-regulation
TK_Tec_ITK_Y	Q8TDQ0	HAVCR2	Q08881	ITK	Y265	R259H	259	Missense	distal	-6	no	20.501	20.214	PhosphoSitePlus	COSMIC	9.294	Down-regulation
TK_Tec_ITK_Y	Q8TDQ0	HAVCR2	Q08881	ITK	Y265	E262K	262	Missense	distal	-3	no	20.501	20.664	PhosphoSitePlus	COSMIC	9.294	Up-regulation
TK_Tec_ITK_Y	Q13094	LCP2	Q08881	ITK	Y145	P138R	138	Missense	distal	-7	no	12.142	12.742	EPSD	COSMIC;GDSC;CCLE	9.294	Up-regulation
TK_Tec_ITK_Y	Q13094	LCP2	Q08881	ITK	Y145	A143T	143	Missense	proximal	-2	no	12.142	10.584	EPSD	COSMIC;GDSC;CCLE	9.294	Down-regulation
TK_Tec_ITK_Y	Q13094	LCP2	Q08881	ITK	Y145	A143V	143	Missense	proximal	-2	no	12.142	9.497	EPSD	COSMIC	9.294	Down-regulation
TK_Tec_ITK_Y	Q13094	LCP2	Q08881	ITK	Y145	P149T	149	Missense	distal	4	no	12.142	11.824	EPSD	COSMIC	9.294	Down-regulation
TK_Tec_ITK_Y	Q13094	LCP2	Q08881	ITK	Y145	P149L	149	Missense	distal	4	no	12.142	11.509	EPSD	COSMIC	9.294	Down-regulation
TK_Tec_ITK_Y	Q13094	LCP2	Q08881	ITK	Y173	P167S	167	Missense	distal	-6	no	18.517	18.450	PhosphoSitePlus	COSMIC	9.294	Down-regulation
TK_Tec_ITK_Y	Q13094	LCP2	Q08881	ITK	Y173	S171F	171	Missense	proximal	-2	no	18.517	16.640	PhosphoSitePlus	COSMIC	9.294	Down-regulation
TK_Tec_ITK_Y	Q13094	LCP2	Q08881	ITK	Y380	S376F	376	Missense	distal	-4	no	12.813	12.229	EPSD	COSMIC	9.294	Down-regulation
TK_Tec_ITK_Y	Q13094	LCP2	Q08881	ITK	Y459	Y459N	459	Missense	central	0	yes	11.079	0.000	EPSD	COSMIC	9.294	Loss
TK_Tec_ITK_Y	Q13094	LCP2	Q08881	ITK	Y459	P458Q	458	Missense	proximal	-1	no	11.079	10.863	EPSD	COSMIC;GDSC;CCLE	9.294	Down-regulation
TK_Tec_ITK_Y	Q13094	LCP2	Q08881	ITK	Y459	M462I	462	Missense	distal	3	no	11.079	11.145	EPSD	COSMIC	9.294	Up-regulation
TK_Csk_CSK_Y	P06239	LCK	P41240	CSK	Y72	D77N	77	Missense	distal	5	no	43.094	43.720	EPSD	COSMIC	33.668	Up-regulation
TK_Csk_CSK_Y	P06239	LCK	P41240	CSK	Y72	G78R	78	Missense	distal	6	no	43.094	43.239	EPSD	COSMIC	33.668	Up-regulation
TK_Csk_CSK_Y	P06239	LCK	P41240	CSK	Y394	L388F	388	Missense	distal	-6	no	46.590	45.836	EPSD	COSMIC	33.668	Down-regulation
TK_Csk_CSK_Y	P06239	LCK	P41240	CSK	Y394	D391N	391	Missense	distal	-3	no	46.590	32.347	EPSD	COSMIC	33.668	Loss
TK_Csk_CSK_Y	P06239	LCK	P41240	CSK	Y394	A396V	396	Missense	proximal	2	no	46.590	40.231	EPSD	COSMIC;GDSC;CCLE	33.668	Down-regulation
TK_Csk_CSK_Y	P06239	LCK	P41240	CSK	Y394	L388I	388	Missense	distal	-6	no	46.590	45.109	EPSD	COSMIC	33.668	Down-regulation
TK_Csk_CSK_Y	P06239	LCK	P41240	CSK	Y394	R387C	387	Missense	distal	-7	no	46.590	46.823	EPSD	COSMIC	33.668	Up-regulation
TK_Csk_CSK_Y	P06239	LCK	P41240	CSK	Y505	G503D	503	Missense	proximal	-2	no	101.250	102.127	PhosphoSitePlus	COSMIC	33.668	Up-regulation
TK_Csk_CSK_Y	P06239	LCK	P41240	CSK	Y505	A500T	500	Missense	distal	-5	no	101.250	99.468	PhosphoSitePlus	COSMIC;GDSC;CCLE	33.668	Down-regulation
TK_Csk_CSK_Y	P06239	LCK	P41240	CSK	Y505	Q508H	508	Missense	distal	3	no	101.250	100.941	PhosphoSitePlus	COSMIC	33.668	Down-regulation
TK_Csk_CSK_Y	P12931	SRC	P41240	CSK	Y419	A421V	421	Missense	proximal	2	no	34.876	28.518	EPSD;PhosphoSitePlus	COSMIC	33.668	Loss
TK_Csk_CSK_Y	P12931	SRC	P41240	CSK	Y419	Y419H	419	Missense	central	0	yes	34.876	0.000	EPSD;PhosphoSitePlus	COSMIC	33.668	Loss
TK_Csk_CSK_Y	P12931	SRC	P41240	CSK	Y530	Q531K	531	Missense	proximal	1	no	115.622	101.885	PhosphoSitePlus;EPSD	COSMIC	33.668	Down-regulation
TK_Csk_CSK_Y	P12931	SRC	P41240	CSK	Y530	E527D	527	Missense	distal	-3	no	115.622	112.067	PhosphoSitePlus;EPSD	COSMIC	33.668	Down-regulation
TK_Csk_CSK_Y	P12931	SRC	P41240	CSK	Y530	N535H	535	Missense	distal	5	no	115.622	115.285	PhosphoSitePlus;EPSD	COSMIC	33.668	Down-regulation
TK_Csk_CSK_Y	P12931	SRC	P41240	CSK	Y530	E534D	534	Missense	distal	4	no	115.622	115.133	PhosphoSitePlus;EPSD	COSMIC	33.668	Down-regulation
TK_Csk_CSK_Y	P07947	YES1	P41240	CSK	Y32	S26G	26	Missense	distal	-6	no	41.419	37.565	EPSD	COSMIC	33.668	Down-regulation
TK_Csk_CSK_Y	P07947	YES1	P41240	CSK	Y32	A34T	34	Missense	proximal	2	no	41.419	35.984	EPSD	COSMIC	33.668	Down-regulation
TK_Csk_CSK_Y	P07947	YES1	P41240	CSK	Y32	P36L	36	Missense	distal	4	no	41.419	38.176	EPSD	COSMIC	33.668	Down-regulation
TK_Csk_CSK_Y	P07947	YES1	P41240	CSK	Y537	E541V	541	Missense	distal	4	no	109.039	106.273	PhosphoSitePlus	COSMIC	33.668	Down-regulation
TK_Csk_CSK_Y	P07947	YES1	P41240	CSK	Y537	T533A	533	Missense	distal	-4	no	109.039	106.882	PhosphoSitePlus	COSMIC;GDSC;CCLE	33.668	Down-regulation
TK_Csk_CSK_Y	P08631	HCK	P41240	CSK	Y411	V405A	405	Missense	distal	-6	no	46.680	49.677	PhosphoSitePlus	COSMIC	33.668	Up-regulation
TK_Csk_CSK_Y	P08631	HCK	P41240	CSK	Y411	E410K	410	Missense	proximal	-1	no	46.680	36.367	PhosphoSitePlus	COSMIC	33.668	Down-regulation
TK_Csk_CSK_Y	P08631	HCK	P41240	CSK	Y411	D408G	408	Missense	distal	-3	no	46.680	34.110	PhosphoSitePlus	COSMIC	33.668	Down-regulation
TK_Csk_CSK_Y	P08631	HCK	P41240	CSK	Y411	T412K	412	Missense	proximal	1	no	46.680	37.706	PhosphoSitePlus	COSMIC	33.668	Down-regulation
TK_Csk_CSK_Y	P08631	HCK	P41240	CSK	Y411	G416R	416	Missense	distal	5	no	46.680	47.042	PhosphoSitePlus	COSMIC	33.668	Up-regulation
TK_Csk_CSK_Y	P08631	HCK	P41240	CSK	Y411	E415K	415	Missense	distal	4	no	46.680	43.199	PhosphoSitePlus	COSMIC	33.668	Down-regulation
TK_Csk_CSK_Y	P08631	HCK	P41240	CSK	Y411	N409K	409	Missense	proximal	-2	no	46.680	46.131	PhosphoSitePlus	COSMIC	33.668	Down-regulation
TK_Csk_CSK_Y	P08631	HCK	P41240	CSK	Y522	T516M	516	Missense	distal	-6	no	100.465	97.146	EPSD	COSMIC	33.668	Down-regulation
TK_Csk_CSK_Y	P08631	HCK	P41240	CSK	Y522	Q523L	523	Missense	proximal	1	no	100.465	85.138	EPSD	COSMIC	33.668	Down-regulation
TK_Csk_CSK_Y	P08631	HCK	P41240	CSK	Y522	Q525K	525	Missense	distal	3	no	100.465	99.894	EPSD	COSMIC	33.668	Down-regulation
TK_Csk_CSK_Y	P08631	HCK	P41240	CSK	Y522	A517T	517	Missense	distal	-5	no	100.465	98.683	EPSD	COSMIC	33.668	Down-regulation
TK_Csk_CSK_Y	P08631	HCK	P41240	CSK	Y522	E519K	519	Missense	distal	-3	no	100.465	81.915	EPSD	COSMIC	33.668	Down-regulation
TK_Csk_CSK_Y	P08575	PTPRC	P41240	CSK	Y544	D541H	541	Missense	distal	-3	no	44.342	30.953	EPSD	COSMIC	33.668	Loss
TK_Csk_CSK_Y	P06241	FYN	P41240	CSK	Y39	T35I	35	Missense	distal	-4	no	56.255	47.246	EPSD	COSMIC	33.668	Down-regulation
TK_Csk_CSK_Y	P06241	FYN	P41240	CSK	Y39	V44M	44	Missense	distal	5	no	56.255	55.979	EPSD	COSMIC	33.668	Down-regulation
TK_Csk_CSK_Y	P06241	FYN	P41240	CSK	Y39	P34A	34	Missense	distal	-5	no	56.255	56.474	EPSD	COSMIC	33.668	Up-regulation
TK_Csk_CSK_Y	P06241	FYN	P41240	CSK	Y39	P34L	34	Missense	distal	-5	no	56.255	48.137	EPSD	COSMIC	33.668	Down-regulation
TK_Csk_CSK_Y	P06241	FYN	P41240	CSK	Y531	E528Q	528	Missense	distal	-3	no	111.873	101.264	PhosphoSitePlus	COSMIC	33.668	Down-regulation
TK_Csk_CSK_Y	P06241	FYN	P41240	CSK	Y531	Y531H	531	Missense	central	0	yes	111.873	0.000	PhosphoSitePlus	COSMIC	33.668	Loss
TK_Csk_CSK_Y	P06241	FYN	P41240	CSK	Y531	A526V	526	Missense	distal	-5	no	111.873	106.350	PhosphoSitePlus	COSMIC	33.668	Down-regulation
TK_Csk_CSK_Y	P06241	FYN	P41240	CSK	Y531	Y531D	531	Missense	central	0	yes	111.873	0.000	PhosphoSitePlus	COSMIC	33.668	Loss
TK_Csk_CSK_Y	P06241	FYN	P41240	CSK	Y531	Q530R	530	Missense	proximal	-1	no	111.873	99.409	PhosphoSitePlus	COSMIC	33.668	Down-regulation
TK_Csk_CSK_Y	P06241	FYN	P41240	CSK	Y531	N536H	536	Missense	distal	5	no	111.873	111.536	PhosphoSitePlus	COSMIC	33.668	Down-regulation
CMGC_MAPK_ERK5_MAPK7_ST	Q13164	MAPK7	Q13164	MAPK7	T28	A26T	26	Missense	proximal	-2	no	108.435	106.845	EPSD;PhosphoSitePlus	COSMIC	81.800	Down-regulation
CMGC_MAPK_ERK5_MAPK7_ST	Q13164	MAPK7	Q13164	MAPK7	T28	A23T	23	Missense	distal	-5	no	108.435	107.545	EPSD;PhosphoSitePlus	COSMIC	81.800	Down-regulation
CMGC_MAPK_ERK5_MAPK7_ST	Q13164	MAPK7	Q13164	MAPK7	T28	T28I	28	Missense	central	0	yes	108.435	0.000	EPSD;PhosphoSitePlus	COSMIC	81.800	Loss
CMGC_MAPK_ERK5_MAPK7_ST	Q13164	MAPK7	Q13164	MAPK7	S210	R205P	205	Missense	distal	-5	no	91.311	96.043	EPSD	COSMIC	81.800	Up-regulation
CMGC_MAPK_ERK5_MAPK7_ST	Q13164	MAPK7	Q13164	MAPK7	S210	R205C	205	Missense	distal	-5	no	91.311	90.735	EPSD	COSMIC	81.800	Down-regulation
CMGC_MAPK_ERK5_MAPK7_ST	Q13164	MAPK7	Q13164	MAPK7	S282	V289L	289	Missense	distal	7	no	91.233	91.783	EPSD	COSMIC	81.800	Up-regulation
CMGC_MAPK_ERK5_MAPK7_ST	Q13164	MAPK7	Q13164	MAPK7	S282	A288V	288	Missense	distal	6	no	91.233	88.767	EPSD	COSMIC	81.800	Down-regulation
CMGC_MAPK_ERK5_MAPK7_ST	Q13164	MAPK7	Q13164	MAPK7	S282	P281S	281	Missense	proximal	-1	no	91.233	91.414	EPSD	COSMIC	81.800	Up-regulation
CMGC_MAPK_ERK5_MAPK7_ST	Q13164	MAPK7	Q13164	MAPK7	S421	C414Y	414	Missense	distal	-7	no	107.916	108.205	EPSD;PhosphoSitePlus	COSMIC	81.800	Up-regulation
CMGC_MAPK_ERK5_MAPK7_ST	Q13164	MAPK7	Q13164	MAPK7	S433	M431I	431	Missense	proximal	-2	no	106.853	105.828	EPSD;PhosphoSitePlus	COSMIC	81.800	Down-regulation
CMGC_MAPK_ERK5_MAPK7_ST	Q13164	MAPK7	Q13164	MAPK7	S433	P438L	438	Missense	distal	5	no	106.853	105.627	EPSD;PhosphoSitePlus	COSMIC	81.800	Down-regulation
CMGC_MAPK_ERK5_MAPK7_ST	Q13164	MAPK7	Q13164	MAPK7	S496	D493Y	493	Missense	distal	-3	no	102.817	98.877	EPSD;PhosphoSitePlus	COSMIC	81.800	Down-regulation
CMGC_MAPK_ERK5_MAPK7_ST	Q13164	MAPK7	Q13164	MAPK7	S496	A497T	497	Missense	proximal	1	no	102.817	43.261	EPSD;PhosphoSitePlus	COSMIC	81.800	Loss
CMGC_MAPK_ERK5_MAPK7_ST	Q13164	MAPK7	Q13164	MAPK7	S731	P728H	728	Missense	distal	-3	no	100.755	96.955	PhosphoSitePlus;EPSD	COSMIC;GDSC;CCLE	81.800	Down-regulation
CMGC_MAPK_ERK5_MAPK7_ST	Q13164	MAPK7	Q13164	MAPK7	S731	T733I	733	Missense	proximal	2	no	100.755	107.246	PhosphoSitePlus;EPSD	COSMIC	81.800	Up-regulation
CMGC_MAPK_ERK5_MAPK7_ST	Q13164	MAPK7	Q13164	MAPK7	T733	P728H	728	Missense	distal	-5	no	111.960	111.202	EPSD;PhosphoSitePlus	COSMIC;GDSC;CCLE	81.800	Down-regulation
CMGC_MAPK_ERK5_MAPK7_ST	Q13164	MAPK7	Q13164	MAPK7	T733	T733I	733	Missense	central	0	yes	111.960	0.000	EPSD;PhosphoSitePlus	COSMIC	81.800	Loss
CMGC_MAPK_ERK5_MAPK7_ST	Q13164	MAPK7	Q13164	MAPK7	S770	P763S	763	Missense	distal	-7	no	112.602	112.757	EPSD;PhosphoSitePlus	COSMIC	81.800	Up-regulation
CMGC_MAPK_ERK5_MAPK7_ST	Q13164	MAPK7	Q13164	MAPK7	S770	A775D	775	Missense	distal	5	no	112.602	114.870	EPSD;PhosphoSitePlus	COSMIC	81.800	Up-regulation
CMGC_MAPK_ERK5_MAPK7_ST	Q13164	MAPK7	Q13164	MAPK7	S772	A775D	775	Missense	distal	3	no	107.012	108.738	EPSD;PhosphoSitePlus	COSMIC	81.800	Up-regulation
CMGC_MAPK_ERK5_MAPK7_ST	Q13164	MAPK7	Q13164	MAPK7	S774	A775D	775	Missense	proximal	1	no	119.380	106.799	EPSD;PhosphoSitePlus	COSMIC	81.800	Down-regulation
CMGC_MAPK_ERK5_MAPK7_ST	Q13164	MAPK7	Q13164	MAPK7	S774	D780Y	780	Missense	distal	6	no	119.380	112.886	EPSD;PhosphoSitePlus	COSMIC	81.800	Down-regulation
CMGC_MAPK_ERK5_MAPK7_ST	Q13164	MAPK7	Q13164	MAPK7	S776	A775D	775	Missense	proximal	-1	no	106.005	106.326	EPSD	COSMIC	81.800	Up-regulation
CMGC_MAPK_ERK5_MAPK7_ST	Q13164	MAPK7	Q13164	MAPK7	S776	D780Y	780	Missense	distal	4	no	106.005	96.526	EPSD	COSMIC	81.800	Down-regulation
CMGC_MAPK_ERK5_MAPK7_ST	P01100	FOS	Q13164	MAPK7	S102	P101S	101	Missense	proximal	-1	no	91.462	91.643	EPSD	COSMIC	81.800	Up-regulation
CMGC_MAPK_ERK5_MAPK7_ST	P01100	FOS	Q13164	MAPK7	S102	G97R	97	Missense	distal	-5	no	91.462	86.346	EPSD	COSMIC	81.800	Down-regulation
CMGC_MAPK_ERK5_MAPK7_ST	P01100	FOS	Q13164	MAPK7	S102	R108G	108	Missense	distal	6	no	91.462	93.418	EPSD	COSMIC	81.800	Up-regulation
CMGC_MAPK_ERK5_MAPK7_ST	P01100	FOS	Q13164	MAPK7	S102	P95L	95	Missense	distal	-7	no	91.462	92.084	EPSD	COSMIC	81.800	Up-regulation
CMGC_MAPK_ERK5_MAPK7_ST	P01100	FOS	Q13164	MAPK7	S133	E137K	137	Missense	distal	4	no	73.923	89.917	EPSD	COSMIC;GDSC;CCLE	81.800	Gain
CMGC_MAPK_ERK5_MAPK7_ST	P01100	FOS	Q13164	MAPK7	T232	A231V	231	Missense	proximal	-1	no	106.787	107.865	EPSD;PhosphoSitePlus	COSMIC	81.800	Up-regulation
CMGC_MAPK_ERK5_MAPK7_ST	Q02078	MEF2A	Q13164	MAPK7	S98	T103M	103	Missense	distal	5	no	86.031	85.122	EPSD	COSMIC	81.800	Down-regulation
CMGC_MAPK_ERK5_MAPK7_ST	Q02078	MEF2A	Q13164	MAPK7	S98	R94G	94	Missense	distal	-4	no	86.031	86.669	EPSD	COSMIC;GDSC;CCLE	81.800	Up-regulation
CMGC_MAPK_ERK5_MAPK7_ST	Q02078	MEF2A	Q13164	MAPK7	S98	G95A	95	Missense	distal	-3	no	86.031	85.587	EPSD	COSMIC	81.800	Down-regulation
CMGC_MAPK_ERK5_MAPK7_ST	Q02078	MEF2A	Q13164	MAPK7	S177	S178N	178	Missense	proximal	1	no	68.428	85.807	EPSD	COSMIC	81.800	Gain
CMGC_MAPK_ERK5_MAPK7_ST	Q02078	MEF2A	Q13164	MAPK7	S192	G194R	194	Missense	proximal	2	no	94.229	92.018	EPSD	COSMIC	81.800	Down-regulation
CMGC_MAPK_ERK5_MAPK7_ST	Q02078	MEF2A	Q13164	MAPK7	S192	Q197E	197	Missense	distal	5	no	94.229	92.458	EPSD	COSMIC	81.800	Down-regulation
CMGC_MAPK_ERK5_MAPK7_ST	Q02078	MEF2A	Q13164	MAPK7	T319	P323L	323	Missense	distal	4	no	109.400	108.351	EPSD;PhosphoSitePlus	COSMIC	81.800	Down-regulation
CMGC_MAPK_ERK5_MAPK7_ST	Q02078	MEF2A	Q13164	MAPK7	S355	Q351P	351	Missense	distal	-4	no	105.605	102.026	EPSD;PhosphoSitePlus	COSMIC	81.800	Down-regulation
CMGC_MAPK_ERK5_MAPK7_ST	Q02078	MEF2A	Q13164	MAPK7	S355	Q351H	351	Missense	distal	-4	no	105.605	103.815	EPSD;PhosphoSitePlus	COSMIC	81.800	Down-regulation
CMGC_MAPK_ERK5_MAPK7_ST	Q02078	MEF2A	Q13164	MAPK7	S417	Q420P	420	Missense	distal	3	no	83.999	86.206	EPSD	COSMIC	81.800	Up-regulation
CMGC_MAPK_ERK5_MAPK7_ST	Q02078	MEF2A	Q13164	MAPK7	S417	Q424P	424	Missense	distal	7	no	83.999	83.782	EPSD	COSMIC	81.800	Down-regulation
CMGC_MAPK_ERK5_MAPK7_ST	Q02078	MEF2A	Q13164	MAPK7	S417	Q423H	423	Missense	distal	6	no	83.999	81.474	EPSD	COSMIC	81.800	Loss
CMGC_MAPK_ERK5_MAPK7_ST	Q02078	MEF2A	Q13164	MAPK7	S453	S453R	453	Missense	central	0	yes	98.003	0.000	EPSD	COSMIC	81.800	Loss
CMGC_MAPK_ERK5_MAPK7_ST	Q02078	MEF2A	Q13164	MAPK7	S468	S461R	461	Missense	distal	-7	no	81.808	80.992	EPSD	COSMIC	81.800	Loss
CMGC_MAPK_ERK5_MAPK7_ST	Q12959	DLG1	Q13164	MAPK7	S70	S70L	70	Missense	central	0	yes	85.119	0.000	EPSD	COSMIC	81.800	Loss
CMGC_MAPK_ERK5_MAPK7_ST	Q12959	DLG1	Q13164	MAPK7	S86	S89R	89	Missense	distal	3	no	89.177	84.828	EPSD	COSMIC	81.800	Down-regulation
CMGC_MAPK_ERK5_MAPK7_ST	Q12959	DLG1	Q13164	MAPK7	S86	E83D	83	Missense	distal	-3	no	89.177	89.556	EPSD	COSMIC	81.800	Up-regulation
CMGC_MAPK_ERK5_MAPK7_ST	Q12959	DLG1	Q13164	MAPK7	S122	I121V	121	Missense	proximal	-1	no	94.597	94.702	EPSD	COSMIC	81.800	Up-regulation
CMGC_MAPK_ERK5_MAPK7_ST	Q12959	DLG1	Q13164	MAPK7	S158	I160V	160	Missense	proximal	2	no	107.598	101.508	PhosphoSitePlus	COSMIC;CCLE	81.800	Down-regulation
CMGC_MAPK_ERK5_MAPK7_ST	Q12959	DLG1	Q13164	MAPK7	S435	Q439L	439	Missense	distal	4	no	84.313	86.426	EPSD	COSMIC	81.800	Up-regulation
CMGC_MAPK_ERK5_MAPK7_ST	Q12959	DLG1	Q13164	MAPK7	S443	Q439L	439	Missense	distal	-4	no	84.273	83.371	EPSD	COSMIC	81.800	Down-regulation
CMGC_MAPK_ERK5_MAPK7_ST	Q12959	DLG1	Q13164	MAPK7	S448	A453V	453	Missense	distal	5	no	97.159	94.823	EPSD	COSMIC	81.800	Down-regulation
CMGC_MAPK_ERK5_MAPK7_ST	Q12959	DLG1	Q13164	MAPK7	S448	V454I	454	Missense	distal	6	no	97.159	98.923	EPSD	COSMIC;GDSC;CCLE	81.800	Up-regulation
CMGC_MAPK_ERK5_MAPK7_ST	Q12959	DLG1	Q13164	MAPK7	S448	L455I	455	Missense	distal	7	no	97.159	97.515	EPSD	COSMIC	81.800	Up-regulation
CMGC_MAPK_ERK5_MAPK7_ST	Q12959	DLG1	Q13164	MAPK7	S575	Q580E	580	Missense	distal	5	no	89.841	88.070	EPSD	COSMIC	81.800	Down-regulation
CMGC_MAPK_ERK5_MAPK7_ST	Q12959	DLG1	Q13164	MAPK7	S575	S568Y	568	Missense	distal	-7	no	89.841	88.169	EPSD	COSMIC	81.800	Down-regulation
CMGC_MAPK_ERK5_MAPK7_ST	Q12959	DLG1	Q13164	MAPK7	S575	S573G	573	Missense	proximal	-2	no	89.841	87.861	EPSD	COSMIC	81.800	Down-regulation
CMGC_MAPK_ERK5_MAPK7_ST	Q12959	DLG1	Q13164	MAPK7	S575	I569V	569	Missense	distal	-6	no	89.841	86.544	EPSD	COSMIC;GDSC;CCLE	81.800	Down-regulation
CMGC_MAPK_ERK5_MAPK7_ST	Q12959	DLG1	Q13164	MAPK7	S575	R577Q	577	Missense	proximal	2	no	89.841	96.169	EPSD	COSMIC	81.800	Up-regulation
CMGC_MAPK_ERK5_MAPK7_ST	Q12959	DLG1	Q13164	MAPK7	S575	L576F	576	Missense	proximal	1	no	89.841	88.065	EPSD	COSMIC	81.800	Down-regulation
CMGC_MAPK_ERK5_MAPK7_ST	Q12959	DLG1	Q13164	MAPK7	S579	Q580E	580	Missense	proximal	1	no	88.990	72.003	EPSD	COSMIC	81.800	Loss
CMGC_MAPK_ERK5_MAPK7_ST	Q12959	DLG1	Q13164	MAPK7	S579	S573G	573	Missense	distal	-6	no	88.990	91.778	EPSD	COSMIC	81.800	Up-regulation
CMGC_MAPK_ERK5_MAPK7_ST	Q12959	DLG1	Q13164	MAPK7	S579	R577Q	577	Missense	proximal	-2	no	88.990	94.140	EPSD	COSMIC	81.800	Up-regulation
CMGC_MAPK_ERK5_MAPK7_ST	Q12959	DLG1	Q13164	MAPK7	S579	Y585C	585	Missense	distal	6	no	88.990	85.714	EPSD	COSMIC	81.800	Down-regulation
CMGC_MAPK_ERK5_MAPK7_ST	Q12959	DLG1	Q13164	MAPK7	S579	V586D	586	Missense	distal	7	no	88.990	91.534	EPSD	COSMIC	81.800	Up-regulation
CMGC_MAPK_ERK5_MAPK7_ST	Q12959	DLG1	Q13164	MAPK7	S579	L576F	576	Missense	distal	-3	no	88.990	88.288	EPSD	COSMIC	81.800	Down-regulation
CMGC_MAPK_ERK5_MAPK7_ST	Q12959	DLG1	Q13164	MAPK7	S583	R587K	587	Missense	distal	4	no	48.208	90.879	EPSD	COSMIC	81.800	Gain
CMGC_MAPK_ERK5_MAPK7_ST	Q12959	DLG1	Q13164	MAPK7	S598	Q603R	603	Missense	distal	5	no	88.380	84.684	EPSD	COSMIC	81.800	Down-regulation
CMGC_MAPK_ERK5_MAPK7_ST	Q12959	DLG1	Q13164	MAPK7	S598	G604V	604	Missense	distal	6	no	88.380	88.063	EPSD	COSMIC	81.800	Down-regulation
CMGC_MAPK_ERK5_MAPK7_ST	Q12959	DLG1	Q13164	MAPK7	T630	G633V	633	Missense	distal	3	no	80.694	82.455	EPSD	COSMIC	81.800	Gain
CMGC_MAPK_ERK5_MAPK7_ST	Q12959	DLG1	Q13164	MAPK7	S792	V793A	793	Missense	proximal	1	no	16.674	94.087	EPSD	COSMIC	81.800	Gain
CMGC_MAPK_ERK5_MAPK7_ST	Q13163	MAP2K5	Q13164	MAPK7	S129	R125W	125	Missense	distal	-4	no	105.888	107.502	EPSD;PhosphoSitePlus	COSMIC	81.800	Up-regulation
CMGC_MAPK_ERK5_MAPK7_ST	Q13163	MAP2K5	Q13164	MAPK7	S129	S132N	132	Missense	distal	3	no	105.888	102.089	EPSD;PhosphoSitePlus	COSMIC	81.800	Down-regulation
CMGC_MAPK_ERK5_MAPK7_ST	Q13163	MAP2K5	Q13164	MAPK7	S129	R125Q	125	Missense	distal	-4	no	105.888	109.285	EPSD;PhosphoSitePlus	COSMIC	81.800	Up-regulation
CMGC_MAPK_ERK5_MAPK7_ST	Q13163	MAP2K5	Q13164	MAPK7	S137	S132N	132	Missense	distal	-5	no	110.596	107.894	EPSD;PhosphoSitePlus	COSMIC	81.800	Down-regulation
CMGC_MAPK_ERK5_MAPK7_ST	Q13163	MAP2K5	Q13164	MAPK7	S142	K147Q	147	Missense	distal	5	no	107.084	109.246	PhosphoSitePlus;EPSD	COSMIC	81.800	Up-regulation
CMGC_MAPK_ERK5_MAPK7_ST	Q13163	MAP2K5	Q13164	MAPK7	S142	S149P	149	Missense	distal	7	no	107.084	106.780	PhosphoSitePlus;EPSD	COSMIC	81.800	Down-regulation
CMGC_MAPK_ERK5_MAPK7_ST	Q13163	MAP2K5	Q13164	MAPK7	S142	S149Y	149	Missense	distal	7	no	107.084	106.739	PhosphoSitePlus;EPSD	COSMIC;GDSC;CCLE	81.800	Down-regulation
CMGC_MAPK_ERK5_MAPK7_ST	Q13163	MAP2K5	Q13164	MAPK7	S144	K147Q	147	Missense	distal	3	no	86.749	85.567	EPSD	COSMIC	81.800	Down-regulation
CMGC_MAPK_ERK5_MAPK7_ST	Q13163	MAP2K5	Q13164	MAPK7	S144	S149P	149	Missense	distal	5	no	86.749	85.856	EPSD	COSMIC	81.800	Down-regulation
CMGC_MAPK_ERK5_MAPK7_ST	Q13163	MAP2K5	Q13164	MAPK7	S144	S149Y	149	Missense	distal	5	no	86.749	84.744	EPSD	COSMIC;GDSC;CCLE	81.800	Down-regulation
CMGC_MAPK_ERK5_MAPK7_ST	Q13163	MAP2K5	Q13164	MAPK7	S148	S149P	149	Missense	proximal	1	no	63.739	91.837	EPSD	COSMIC	81.800	Gain
CMGC_MAPK_ERK5_MAPK7_ST	Q13163	MAP2K5	Q13164	MAPK7	S149	L152Q	152	Missense	distal	3	no	106.873	106.057	EPSD;PhosphoSitePlus	COSMIC	81.800	Down-regulation
CMGC_MAPK_ERK5_MAPK7_ST	Q13163	MAP2K5	Q13164	MAPK7	S149	K147Q	147	Missense	proximal	-2	no	106.873	107.707	EPSD;PhosphoSitePlus	COSMIC	81.800	Up-regulation
CMGC_MAPK_ERK5_MAPK7_ST	Q13163	MAP2K5	Q13164	MAPK7	S149	S149P	149	Missense	central	0	yes	106.873	0.000	EPSD;PhosphoSitePlus	COSMIC	81.800	Loss
CMGC_MAPK_ERK5_MAPK7_ST	Q13163	MAP2K5	Q13164	MAPK7	S149	S149Y	149	Missense	central	0	yes	106.873	0.000	EPSD;PhosphoSitePlus	COSMIC;GDSC;CCLE	81.800	Loss
CMGC_MAPK_ERK5_MAPK7_ST	Q06413	MEF2C	Q13164	MAPK7	T80	V85A	85	Missense	distal	5	no	89.534	91.870	EPSD	COSMIC	81.800	Up-regulation
CMGC_MAPK_ERK5_MAPK7_ST	Q06413	MEF2C	Q13164	MAPK7	T80	E74K	74	Missense	distal	-6	no	89.534	86.013	EPSD	COSMIC	81.800	Down-regulation
CMGC_MAPK_ERK5_MAPK7_ST	Q06413	MEF2C	Q13164	MAPK7	T80	P75L	75	Missense	distal	-5	no	89.534	90.835	EPSD	COSMIC	81.800	Up-regulation
CMGC_MAPK_ERK5_MAPK7_ST	Q06413	MEF2C	Q13164	MAPK7	T80	S78T	78	Missense	proximal	-2	no	89.534	87.143	EPSD	COSMIC	81.800	Down-regulation
CMGC_MAPK_ERK5_MAPK7_ST	Q06413	MEF2C	Q13164	MAPK7	T80	R79W	79	Missense	proximal	-1	no	89.534	89.640	EPSD	COSMIC	81.800	Up-regulation
CMGC_MAPK_ERK5_MAPK7_ST	Q06413	MEF2C	Q13164	MAPK7	T80	E77K	77	Missense	distal	-3	no	89.534	87.819	EPSD	COSMIC	81.800	Down-regulation
CMGC_MAPK_ERK5_MAPK7_ST	Q06413	MEF2C	Q13164	MAPK7	S98	K91E	91	Missense	distal	-7	no	96.927	98.954	EPSD	COSMIC	81.800	Up-regulation
CMGC_MAPK_ERK5_MAPK7_ST	Q06413	MEF2C	Q13164	MAPK7	S98	C96S	96	Missense	proximal	-2	no	96.927	105.142	EPSD	COSMIC;GDSC;CCLE	81.800	Up-regulation
CMGC_MAPK_ERK5_MAPK7_ST	Q06413	MEF2C	Q13164	MAPK7	S98	D100N	100	Missense	proximal	2	no	96.927	94.319	EPSD	COSMIC	81.800	Down-regulation
CMGC_MAPK_ERK5_MAPK7_ST	Q06413	MEF2C	Q13164	MAPK7	S98	G95C	95	Missense	distal	-3	no	96.927	89.504	EPSD	COSMIC	81.800	Down-regulation
CMGC_MAPK_ERK5_MAPK7_ST	Q06413	MEF2C	Q13164	MAPK7	S98	K91N	91	Missense	distal	-7	no	96.927	96.760	EPSD	COSMIC	81.800	Down-regulation
CMGC_MAPK_ERK5_MAPK7_ST	Q06413	MEF2C	Q13164	MAPK7	S98	A103S	103	Missense	distal	5	no	96.927	97.743	EPSD	COSMIC	81.800	Up-regulation
CMGC_MAPK_ERK5_MAPK7_ST	Q06413	MEF2C	Q13164	MAPK7	S98	K91R	91	Missense	distal	-7	no	96.927	96.550	EPSD	COSMIC	81.800	Down-regulation
CMGC_MAPK_ERK5_MAPK7_ST	Q06413	MEF2C	Q13164	MAPK7	S110	V107I	107	Missense	distal	-3	no	95.125	99.878	EPSD	COSMIC	81.800	Up-regulation
CMGC_MAPK_ERK5_MAPK7_ST	Q06413	MEF2C	Q13164	MAPK7	S110	S110C	110	Missense	central	0	yes	95.125	0.000	EPSD	COSMIC	81.800	Loss
CMGC_MAPK_ERK5_MAPK7_ST	Q06413	MEF2C	Q13164	MAPK7	S110	S110R	110	Missense	central	0	yes	95.125	0.000	EPSD	COSMIC	81.800	Loss
CMGC_MAPK_ERK5_MAPK7_ST	Q06413	MEF2C	Q13164	MAPK7	S110	A103S	103	Missense	distal	-7	no	95.125	94.863	EPSD	COSMIC	81.800	Down-regulation
CMGC_MAPK_ERK5_MAPK7_ST	Q06413	MEF2C	Q13164	MAPK7	S110	S106R	106	Missense	distal	-4	no	95.125	93.871	EPSD	COSMIC	81.800	Down-regulation
CMGC_MAPK_ERK5_MAPK7_ST	Q06413	MEF2C	Q13164	MAPK7	S110	S106N	106	Missense	distal	-4	no	95.125	96.244	EPSD	COSMIC	81.800	Up-regulation
CMGC_MAPK_ERK5_MAPK7_ST	Q06413	MEF2C	Q13164	MAPK7	S110	S106T	106	Missense	distal	-4	no	95.125	93.432	EPSD	COSMIC	81.800	Down-regulation
CMGC_MAPK_ERK5_MAPK7_ST	Q06413	MEF2C	Q13164	MAPK7	S110	S106G	106	Missense	distal	-4	no	95.125	94.509	EPSD	COSMIC	81.800	Down-regulation
CMGC_MAPK_ERK5_MAPK7_ST	Q06413	MEF2C	Q13164	MAPK7	S228	S222P	222	Missense	distal	-6	no	82.715	83.241	EPSD	COSMIC	81.800	Up-regulation
CMGC_MAPK_ERK5_MAPK7_ST	Q06413	MEF2C	Q13164	MAPK7	S228	N221H	221	Missense	distal	-7	no	82.715	83.381	EPSD	COSMIC	81.800	Up-regulation
CMGC_MAPK_ERK5_MAPK7_ST	Q06413	MEF2C	Q13164	MAPK7	T293	S287F	287	Missense	distal	-6	no	94.140	92.965	EPSD	COSMIC	81.800	Down-regulation
CMGC_MAPK_ERK5_MAPK7_ST	Q06413	MEF2C	Q13164	MAPK7	T293	V298I	298	Missense	distal	5	no	94.140	96.244	EPSD	COSMIC	81.800	Up-regulation
CMGC_MAPK_ERK5_MAPK7_ST	Q06413	MEF2C	Q13164	MAPK7	T293	P294Q	294	Missense	proximal	1	no	94.140	82.618	EPSD	COSMIC	81.800	Down-regulation
CMGC_MAPK_ERK5_MAPK7_ST	Q06413	MEF2C	Q13164	MAPK7	T293	V296I	296	Missense	distal	3	no	94.140	93.199	EPSD	COSMIC	81.800	Down-regulation
CMGC_MAPK_ERK5_MAPK7_ST	Q06413	MEF2C	Q13164	MAPK7	T300	Q306K	306	Missense	distal	6	no	92.300	90.745	EPSD	COSMIC	81.800	Down-regulation
CMGC_MAPK_ERK5_MAPK7_ST	Q06413	MEF2C	Q13164	MAPK7	T300	V298I	298	Missense	proximal	-2	no	92.300	92.913	EPSD	COSMIC	81.800	Up-regulation
CMGC_MAPK_ERK5_MAPK7_ST	Q06413	MEF2C	Q13164	MAPK7	T300	P294Q	294	Missense	distal	-6	no	92.300	93.162	EPSD	COSMIC	81.800	Up-regulation
CMGC_MAPK_ERK5_MAPK7_ST	Q06413	MEF2C	Q13164	MAPK7	T300	V296I	296	Missense	distal	-4	no	92.300	95.298	EPSD	COSMIC	81.800	Up-regulation
CMGC_MAPK_ERK5_MAPK7_ST	Q06413	MEF2C	Q13164	MAPK7	T300	P304Q	304	Missense	distal	4	no	92.300	89.137	EPSD	COSMIC	81.800	Down-regulation
CMGC_MAPK_ERK5_MAPK7_ST	Q06413	MEF2C	Q13164	MAPK7	S387	S387P	387	Missense	central	0	yes	104.408	0.000	PhosphoSitePlus	COSMIC	81.800	Loss
CMGC_MAPK_ERK5_MAPK7_ST	Q06413	MEF2C	Q13164	MAPK7	S387	N389S	389	Missense	proximal	2	no	104.408	107.520	PhosphoSitePlus	COSMIC;GDSC	81.800	Up-regulation
CMGC_MAPK_ERK5_MAPK7_ST	Q06413	MEF2C	Q13164	MAPK7	S387	S384C	384	Missense	distal	-3	no	104.408	98.067	PhosphoSitePlus	COSMIC	81.800	Down-regulation
CMGC_MAPK_ERK5_MAPK7_ST	Q06413	MEF2C	Q13164	MAPK7	S387	L388F	388	Missense	proximal	1	no	104.408	102.633	PhosphoSitePlus	COSMIC	81.800	Down-regulation
CMGC_MAPK_ERK5_MAPK7_ST	Q06413	MEF2C	Q13164	MAPK7	S387	L380I	380	Missense	distal	-7	no	104.408	103.583	PhosphoSitePlus	COSMIC	81.800	Down-regulation
CMGC_MAPK_ERK5_MAPK7_ST	Q06413	MEF2C	Q13164	MAPK7	S387	S381G	381	Missense	distal	-6	no	104.408	107.196	PhosphoSitePlus	COSMIC	81.800	Up-regulation
CMGC_MAPK_ERK5_MAPK7_ST	Q06413	MEF2C	Q13164	MAPK7	S387	I390M	390	Missense	distal	3	no	104.408	105.163	PhosphoSitePlus	COSMIC	81.800	Up-regulation
CMGC_MAPK_ERK5_MAPK7_ST	Q06413	MEF2C	Q13164	MAPK7	S387	P394R	394	Missense	distal	7	no	104.408	102.275	PhosphoSitePlus	COSMIC	81.800	Down-regulation
CMGC_MAPK_ERK5_MAPK7_ST	Q06413	MEF2C	Q13164	MAPK7	S387	P394T	394	Missense	distal	7	no	104.408	104.839	PhosphoSitePlus	COSMIC	81.800	Up-regulation
CMGC_MAPK_ERK5_MAPK7_ST	Q06413	MEF2C	Q13164	MAPK7	S396	S396L	396	Missense	central	0	yes	83.625	0.000	EPSD	COSMIC	81.800	Loss
CMGC_MAPK_ERK5_MAPK7_ST	Q06413	MEF2C	Q13164	MAPK7	S396	T402M	402	Missense	distal	6	no	83.625	80.767	EPSD	COSMIC	81.800	Loss
CMGC_MAPK_ERK5_MAPK7_ST	Q06413	MEF2C	Q13164	MAPK7	S396	D400Y	400	Missense	distal	4	no	83.625	74.146	EPSD	COSMIC	81.800	Loss
CMGC_MAPK_ERK5_MAPK7_ST	Q06413	MEF2C	Q13164	MAPK7	S396	N389S	389	Missense	distal	-7	no	83.625	84.230	EPSD	COSMIC;GDSC	81.800	Up-regulation
CMGC_MAPK_ERK5_MAPK7_ST	Q06413	MEF2C	Q13164	MAPK7	S396	I390M	390	Missense	distal	-6	no	83.625	81.303	EPSD	COSMIC	81.800	Loss
CMGC_MAPK_ERK5_MAPK7_ST	Q06413	MEF2C	Q13164	MAPK7	S396	R401T	401	Missense	distal	5	no	83.625	84.475	EPSD	COSMIC	81.800	Up-regulation
CMGC_MAPK_ERK5_MAPK7_ST	Q06413	MEF2C	Q13164	MAPK7	S396	R401K	401	Missense	distal	5	no	83.625	85.158	EPSD	COSMIC	81.800	Up-regulation
CMGC_MAPK_ERK5_MAPK7_ST	Q06413	MEF2C	Q13164	MAPK7	S396	P394R	394	Missense	proximal	-2	no	83.625	78.847	EPSD	COSMIC	81.800	Loss
CMGC_MAPK_ERK5_MAPK7_ST	Q06413	MEF2C	Q13164	MAPK7	S396	P394T	394	Missense	proximal	-2	no	83.625	82.337	EPSD	COSMIC	81.800	Down-regulation
CMGC_MAPK_ERK5_MAPK7_ST	Q06413	MEF2C	Q13164	MAPK7	T404	T402M	402	Missense	proximal	-2	no	82.621	81.968	EPSD	COSMIC	81.800	Down-regulation
CMGC_MAPK_ERK5_MAPK7_ST	Q06413	MEF2C	Q13164	MAPK7	T404	D400Y	400	Missense	distal	-4	no	82.621	80.563	EPSD	COSMIC	81.800	Loss
CMGC_MAPK_ERK5_MAPK7_ST	Q06413	MEF2C	Q13164	MAPK7	T404	P405R	405	Missense	proximal	1	no	82.621	18.542	EPSD	COSMIC	81.800	Loss
CMGC_MAPK_ERK5_MAPK7_ST	Q06413	MEF2C	Q13164	MAPK7	T404	P405T	405	Missense	proximal	1	no	82.621	18.441	EPSD	COSMIC	81.800	Loss
CMGC_MAPK_ERK5_MAPK7_ST	Q06413	MEF2C	Q13164	MAPK7	T404	S406L	406	Missense	proximal	2	no	82.621	80.408	EPSD	COSMIC	81.800	Loss
CMGC_MAPK_ERK5_MAPK7_ST	Q06413	MEF2C	Q13164	MAPK7	T404	R401T	401	Missense	distal	-3	no	82.621	86.296	EPSD	COSMIC	81.800	Up-regulation
CMGC_MAPK_ERK5_MAPK7_ST	Q06413	MEF2C	Q13164	MAPK7	T404	R401K	401	Missense	distal	-3	no	82.621	86.058	EPSD	COSMIC	81.800	Up-regulation
CMGC_MAPK_ERK5_MAPK7_ST	Q06413	MEF2C	Q13164	MAPK7	T404	R407G	407	Missense	distal	3	no	82.621	84.288	EPSD	COSMIC	81.800	Up-regulation
CMGC_MAPK_ERK5_MAPK7_ST	Q06413	MEF2C	Q13164	MAPK7	S406	R407G	407	Missense	proximal	1	no	29.947	83.809	EPSD	COSMIC	81.800	Gain
CMGC_MAPK_ERK5_MAPK7_ST	Q06413	MEF2C	Q13164	MAPK7	S419	D422Y	422	Missense	distal	3	no	111.494	107.298	EPSD	COSMIC	81.800	Down-regulation
CMGC_MAPK_ERK5_MAPK7_ST	Q06413	MEF2C	Q13164	MAPK7	S419	P420H	420	Missense	proximal	1	no	111.494	72.955	EPSD	COSMIC	81.800	Loss
CMGC_MAPK_ERK5_MAPK7_ST	Q06413	MEF2C	Q13164	MAPK7	S419	E415K	415	Missense	distal	-4	no	111.494	112.349	EPSD	COSMIC	81.800	Up-regulation
CMGC_MAPK_ERK5_MAPK7_ST	Q06413	MEF2C	Q13164	MAPK7	S419	T412M	412	Missense	distal	-7	no	111.494	110.623	EPSD	COSMIC	81.800	Down-regulation
CMGC_MAPK_ERK5_MAPK7_ST	Q06413	MEF2C	Q13164	MAPK7	S419	A416V	416	Missense	distal	-3	no	111.494	106.043	EPSD	COSMIC	81.800	Down-regulation
CMGC_MAPK_ERK5_MAPK7_ST	Q06413	MEF2C	Q13164	MAPK7	S419	S419P	419	Missense	central	0	yes	111.494	0.000	EPSD	COSMIC	81.800	Loss
CMGC_MAPK_ERK5_MAPK7_ST	Q06413	MEF2C	Q13164	MAPK7	S419	R413C	413	Missense	distal	-6	no	111.494	105.870	EPSD	COSMIC	81.800	Down-regulation
CMGC_MAPK_ERK5_MAPK7_ST	Q06413	MEF2C	Q13164	MAPK7	S419	E415D	415	Missense	distal	-4	no	111.494	113.231	EPSD	COSMIC	81.800	Up-regulation
CMGC_MAPK_ERK5_MAPK7_ST	Q06413	MEF2C	Q13164	MAPK7	S419	R413H	413	Missense	distal	-6	no	111.494	115.751	EPSD	COSMIC	81.800	Up-regulation
CMGC_MAPK_ERK5_MAPK7_ST	Q06413	MEF2C	Q13164	MAPK7	S419	R418G	418	Missense	proximal	-1	no	111.494	111.272	EPSD	COSMIC	81.800	Down-regulation
CMGC_MAPK_ERK5_MAPK7_ST	Q06413	MEF2C	Q13164	MAPK7	S419	S419L	419	Missense	central	0	yes	111.494	0.000	EPSD	COSMIC	81.800	Loss
CMGC_MAPK_ERK5_MAPK7_ST	Q06413	MEF2C	Q13164	MAPK7	S419	S419N	419	Missense	central	0	yes	111.494	0.000	EPSD	COSMIC	81.800	Loss
CMGC_MAPK_ERK5_MAPK7_ST	Q06413	MEF2C	Q13164	MAPK7	S445	S445L	445	Missense	central	0	yes	82.858	0.000	EPSD	COSMIC	81.800	Loss
CMGC_MAPK_ERK5_MAPK7_ST	Q06413	MEF2C	Q13164	MAPK7	S445	R440W	440	Missense	distal	-5	no	82.858	85.277	EPSD	COSMIC	81.800	Up-regulation
CMGC_MAPK_ERK5_MAPK7_ST	Q06413	MEF2C	Q13164	MAPK7	S445	S445F	445	Missense	central	0	yes	82.858	0.000	EPSD	COSMIC	81.800	Loss
CMGC_MAPK_ERK5_MAPK7_ST	Q06413	MEF2C	Q13164	MAPK7	S445	P452H	452	Missense	distal	7	no	82.858	83.326	EPSD	COSMIC	81.800	Up-regulation
CMGC_MAPK_ERK5_MAPK7_ST	Q06413	MEF2C	Q13164	MAPK7	S445	E442K	442	Missense	distal	-3	no	82.858	81.144	EPSD	COSMIC;GDSC;CCLE	81.800	Loss
CMGC_MAPK_ERK5_MAPK7_ST	Q06413	MEF2C	Q13164	MAPK7	S445	D438Y	438	Missense	distal	-7	no	82.858	80.336	EPSD	COSMIC	81.800	Loss
CMGC_MAPK_ERK5_MAPK7_ST	Q06413	MEF2C	Q13164	MAPK7	S445	R451K	451	Missense	distal	6	no	82.858	87.308	EPSD	COSMIC	81.800	Up-regulation
CMGC_MAPK_ERK5_MAPK7_ST	Q06413	MEF2C	Q13164	MAPK7	S445	R440K	440	Missense	distal	-5	no	82.858	87.682	EPSD	COSMIC	81.800	Up-regulation
CMGC_MAPK_ERK5_MAPK7_ST	Q06413	MEF2C	Q13164	MAPK7	S453	R457K	457	Missense	distal	4	no	39.505	82.177	EPSD	COSMIC	81.800	Gain
CMGC_MAPK_ERK5_MAPK7_ST	P29590	PML	Q13164	MAPK7	T28	P26S	26	Missense	proximal	-2	no	97.259	98.362	EPSD	COSMIC	81.800	Up-regulation
CMGC_MAPK_ERK5_MAPK7_ST	P29590	PML	Q13164	MAPK7	S38	R44Q	44	Missense	distal	6	no	86.741	92.745	EPSD	COSMIC	81.800	Up-regulation
CMGC_MAPK_ERK5_MAPK7_ST	P29590	PML	Q13164	MAPK7	S40	R44Q	44	Missense	distal	4	no	63.464	90.801	EPSD	COSMIC	81.800	Gain
CMGC_MAPK_ERK5_MAPK7_ST	P29590	PML	Q13164	MAPK7	S399	Q392K	392	Missense	distal	-7	no	84.948	84.407	EPSD	COSMIC	81.800	Down-regulation
CMGC_MAPK_ERK5_MAPK7_ST	P29590	PML	Q13164	MAPK7	S505	P506L	506	Missense	proximal	1	no	92.499	74.041	EPSD	COSMIC	81.800	Loss
CMGC_MAPK_ERK5_MAPK7_ST	P29590	PML	Q13164	MAPK7	S514	S514P	514	Missense	central	0	yes	82.293	0.000	EPSD	COSMIC	81.800	Loss
CMGC_MAPK_ERK5_MAPK7_ST	P29590	PML	Q13164	MAPK7	S518	S514P	514	Missense	distal	-4	no	91.672	90.237	EPSD	COSMIC	81.800	Down-regulation
CMGC_MAPK_ERK5_MAPK7_ST	P29590	PML	Q13164	MAPK7	S542	A546V	546	Missense	distal	4	no	83.652	69.282	EPSD	COSMIC	81.800	Loss
CMGC_MAPK_ERK5_MAPK7_ST	P29590	PML	Q13164	MAPK7	S561	S562P	562	Missense	proximal	1	no	60.729	88.827	EPSD	COSMIC	81.800	Gain
CMGC_MAPK_ERK5_MAPK7_ST	P29590	PML	Q13164	MAPK7	S578	S583L	583	Missense	distal	5	no	96.073	93.953	EPSD	COSMIC	81.800	Down-regulation
CMGC_MAPK_ERK5_MAPK7_ST	P29590	PML	Q13164	MAPK7	S579	S583L	583	Missense	distal	4	no	86.463	81.758	EPSD	COSMIC	81.800	Loss
CMGC_MAPK_ERK5_MAPK7_ST	P29590	PML	Q13164	MAPK7	S580	S583L	583	Missense	distal	3	no	87.629	86.678	EPSD	COSMIC	81.800	Down-regulation
CMGC_MAPK_ERK5_MAPK7_ST	P29590	PML	Q13164	MAPK7	T592	V595L	595	Missense	distal	3	no	85.995	85.965	EPSD	COSMIC	81.800	Down-regulation
CMGC_MAPK_ERK5_MAPK7_ST	P29590	PML	Q13164	MAPK7	S625	R632W	632	Missense	distal	7	no	79.344	81.969	EPSD	COSMIC	81.800	Gain
CMGC_MAPK_ERK5_MAPK7_ST	O00141	SGK1	Q13164	MAPK7	S74	Q81R	81	Missense	distal	7	no	91.525	89.175	EPSD	COSMIC	81.800	Down-regulation
CMGC_MAPK_ERK5_MAPK7_ST	O00141	SGK1	Q13164	MAPK7	S74	N72K	72	Missense	proximal	-2	no	91.525	90.633	EPSD	COSMIC	81.800	Down-regulation
CMGC_MAPK_ERK5_MAPK7_ST	O00141	SGK1	Q13164	MAPK7	S74	S78A	78	Missense	distal	4	no	91.525	85.999	EPSD	COSMIC	81.800	Down-regulation
CMGC_MAPK_ERK5_MAPK7_ST	O00141	SGK1	Q13164	MAPK7	S74	A71T	71	Missense	distal	-3	no	91.525	90.317	EPSD	COSMIC	81.800	Down-regulation
CMGC_MAPK_ERK5_MAPK7_ST	O00141	SGK1	Q13164	MAPK7	S74	P75S	75	Missense	proximal	1	no	91.525	63.427	EPSD	COSMIC	81.800	Loss
CMGC_MAPK_ERK5_MAPK7_ST	O00141	SGK1	Q13164	MAPK7	S74	N72Y	72	Missense	proximal	-2	no	91.525	90.784	EPSD	COSMIC;CCLE	81.800	Down-regulation
CMGC_MAPK_ERK5_MAPK7_ST	O00141	SGK1	Q13164	MAPK7	S78	Q81R	81	Missense	distal	3	no	107.871	105.289	PhosphoSitePlus	COSMIC	81.800	Down-regulation
CMGC_MAPK_ERK5_MAPK7_ST	O00141	SGK1	Q13164	MAPK7	S78	N72K	72	Missense	distal	-6	no	107.871	100.237	PhosphoSitePlus	COSMIC	81.800	Down-regulation
CMGC_MAPK_ERK5_MAPK7_ST	O00141	SGK1	Q13164	MAPK7	S78	S78A	78	Missense	central	0	yes	107.871	0.000	PhosphoSitePlus	COSMIC	81.800	Loss
CMGC_MAPK_ERK5_MAPK7_ST	O00141	SGK1	Q13164	MAPK7	S78	A71T	71	Missense	distal	-7	no	107.871	108.272	PhosphoSitePlus	COSMIC	81.800	Up-regulation
CMGC_MAPK_ERK5_MAPK7_ST	O00141	SGK1	Q13164	MAPK7	S78	P75S	75	Missense	distal	-3	no	107.871	105.219	PhosphoSitePlus	COSMIC	81.800	Down-regulation
CMGC_MAPK_ERK5_MAPK7_ST	O00141	SGK1	Q13164	MAPK7	S78	N72Y	72	Missense	distal	-6	no	107.871	103.253	PhosphoSitePlus	COSMIC;CCLE	81.800	Down-regulation
CMGC_MAPK_ERK5_MAPK7_ST	O00141	SGK1	Q13164	MAPK7	S377	L382F	382	Missense	distal	5	no	85.464	85.151	EPSD	COSMIC	81.800	Down-regulation
CMGC_MAPK_ERK5_MAPK7_ST	O00141	SGK1	Q13164	MAPK7	S377	P371L	371	Missense	distal	-6	no	85.464	82.924	EPSD	COSMIC	81.800	Down-regulation
CMGC_MAPK_ERK5_MAPK7_ST	P14921	ETS1	Q13164	MAPK7	S26	M29V	29	Missense	distal	3	no	95.703	95.889	EPSD	COSMIC	81.800	Up-regulation
CMGC_MAPK_ERK5_MAPK7_ST	P14921	ETS1	Q13164	MAPK7	S26	L23F	23	Missense	distal	-3	no	95.703	95.002	EPSD	COSMIC	81.800	Down-regulation
CMGC_MAPK_ERK5_MAPK7_ST	P14921	ETS1	Q13164	MAPK7	S26	L23V	23	Missense	distal	-3	no	95.703	90.600	EPSD	COSMIC	81.800	Down-regulation
CMGC_MAPK_ERK5_MAPK7_ST	P14921	ETS1	Q13164	MAPK7	S26	D33G	33	Missense	distal	7	no	95.703	93.964	EPSD	COSMIC	81.800	Down-regulation
CMGC_MAPK_ERK5_MAPK7_ST	P14921	ETS1	Q13164	MAPK7	T38	S40N	40	Missense	proximal	2	no	108.456	105.345	PhosphoSitePlus	COSMIC	81.800	Down-regulation
CMGC_MAPK_ERK5_MAPK7_ST	P14921	ETS1	Q13164	MAPK7	T38	M45I	45	Missense	distal	7	no	108.456	109.083	PhosphoSitePlus	COSMIC	81.800	Up-regulation
CMGC_MAPK_ERK5_MAPK7_ST	P14921	ETS1	Q13164	MAPK7	T38	P39S	39	Missense	proximal	1	no	108.456	80.358	PhosphoSitePlus	COSMIC	81.800	Loss
CMGC_MAPK_ERK5_MAPK7_ST	P14921	ETS1	Q13164	MAPK7	T38	D33G	33	Missense	distal	-5	no	108.456	106.154	PhosphoSitePlus	COSMIC	81.800	Down-regulation
CMGC_MAPK_ERK5_MAPK7_ST	P14921	ETS1	Q13164	MAPK7	T38	P35L	35	Missense	distal	-3	no	108.456	106.097	PhosphoSitePlus	COSMIC	81.800	Down-regulation
CMGC_MAPK_ERK5_MAPK7_ST	P14921	ETS1	Q13164	MAPK7	T38	M44I	44	Missense	distal	6	no	108.456	109.876	PhosphoSitePlus	COSMIC;CCLE	81.800	Up-regulation
CMGC_MAPK_ERK5_MAPK7_ST	P14921	ETS1	Q13164	MAPK7	S46	F53L	53	Missense	distal	7	no	88.802	89.774	EPSD	COSMIC	81.800	Up-regulation
CMGC_MAPK_ERK5_MAPK7_ST	P14921	ETS1	Q13164	MAPK7	S46	S40N	40	Missense	distal	-6	no	88.802	93.980	EPSD	COSMIC	81.800	Up-regulation
CMGC_MAPK_ERK5_MAPK7_ST	P14921	ETS1	Q13164	MAPK7	S46	M45I	45	Missense	proximal	-1	no	88.802	88.719	EPSD	COSMIC	81.800	Down-regulation
CMGC_MAPK_ERK5_MAPK7_ST	P14921	ETS1	Q13164	MAPK7	S46	P39S	39	Missense	distal	-7	no	88.802	88.957	EPSD	COSMIC	81.800	Up-regulation
CMGC_MAPK_ERK5_MAPK7_ST	P14921	ETS1	Q13164	MAPK7	S46	Q47E	47	Missense	proximal	1	no	88.802	71.815	EPSD	COSMIC	81.800	Loss
CMGC_MAPK_ERK5_MAPK7_ST	P14921	ETS1	Q13164	MAPK7	S46	M44I	44	Missense	proximal	-2	no	88.802	87.776	EPSD	COSMIC;CCLE	81.800	Down-regulation
CMGC_MAPK_ERK5_MAPK7_ST	P14921	ETS1	Q13164	MAPK7	S54	Q60H	60	Missense	distal	6	no	89.408	86.882	EPSD	COSMIC	81.800	Down-regulation
CMGC_MAPK_ERK5_MAPK7_ST	P14921	ETS1	Q13164	MAPK7	S54	F53L	53	Missense	proximal	-1	no	89.408	89.340	EPSD	COSMIC	81.800	Down-regulation
CMGC_MAPK_ERK5_MAPK7_ST	P14921	ETS1	Q13164	MAPK7	S54	G55C	55	Missense	proximal	1	no	89.408	38.971	EPSD	COSMIC	81.800	Loss
CMGC_MAPK_ERK5_MAPK7_ST	P14921	ETS1	Q13164	MAPK7	S54	T57S	57	Missense	distal	3	no	89.408	88.845	EPSD	COSMIC	81.800	Down-regulation
CMGC_MAPK_ERK5_MAPK7_ST	P14921	ETS1	Q13164	MAPK7	S54	Q47E	47	Missense	distal	-7	no	89.408	90.894	EPSD	COSMIC	81.800	Up-regulation
CMGC_MAPK_ERK5_MAPK7_ST	P14921	ETS1	Q13164	MAPK7	T265	R263H	263	Missense	proximal	-2	no	86.492	92.734	EPSD	COSMIC	81.800	Up-regulation
CMGC_MAPK_ERK5_MAPK7_ST	P14921	ETS1	Q13164	MAPK7	T265	S267P	267	Missense	proximal	2	no	86.492	80.336	EPSD	COSMIC;CCLE	81.800	Loss
CMGC_MAPK_ERK5_MAPK7_ST	P14921	ETS1	Q13164	MAPK7	T265	S260G	260	Missense	distal	-5	no	86.492	86.474	EPSD	COSMIC;CCLE	81.800	Down-regulation
CMGC_MAPK_ERK5_MAPK7_ST	P14921	ETS1	Q13164	MAPK7	T265	W268L	268	Missense	distal	3	no	86.492	88.278	EPSD	COSMIC	81.800	Up-regulation
CMGC_MAPK_ERK5_MAPK7_ST	P14921	ETS1	Q13164	MAPK7	T265	C261W	261	Missense	distal	-4	no	86.492	89.422	EPSD	COSMIC	81.800	Up-regulation
CMGC_DYRK_HIPK_HIPK2_ST	Q9P1Z0	ZBTB4	Q9H2X6	HIPK2	S90	A83T	83	Missense	distal	-7	no	101.860	100.332	EPSD	COSMIC	98.777	Down-regulation
CMGC_DYRK_HIPK_HIPK2_ST	Q9P1Z0	ZBTB4	Q9H2X6	HIPK2	S91	S98F	98	Missense	distal	7	no	100.976	100.417	EPSD	COSMIC	98.777	Down-regulation
CMGC_DYRK_HIPK_HIPK2_ST	Q9P1Z0	ZBTB4	Q9H2X6	HIPK2	S92	S98F	98	Missense	distal	6	no	101.620	101.138	EPSD	COSMIC	98.777	Down-regulation
CMGC_DYRK_HIPK_HIPK2_ST	Q9P1Z0	ZBTB4	Q9H2X6	HIPK2	S93	S98F	98	Missense	distal	5	no	99.614	99.745	EPSD	COSMIC	98.777	Up-regulation
CMGC_DYRK_HIPK_HIPK2_ST	Q9P1Z0	ZBTB4	Q9H2X6	HIPK2	S104	S110F	110	Missense	distal	6	no	103.114	102.632	EPSD	COSMIC	98.777	Down-regulation
CMGC_DYRK_HIPK_HIPK2_ST	Q9P1Z0	ZBTB4	Q9H2X6	HIPK2	S104	S108F	108	Missense	distal	4	no	103.114	97.037	EPSD	COSMIC	98.777	Loss
CMGC_DYRK_HIPK_HIPK2_ST	Q9P1Z0	ZBTB4	Q9H2X6	HIPK2	S104	S98F	98	Missense	distal	-6	no	103.114	102.916	EPSD	COSMIC	98.777	Down-regulation
CMGC_DYRK_HIPK_HIPK2_ST	Q9P1Z0	ZBTB4	Q9H2X6	HIPK2	S391	L395F	395	Missense	distal	4	no	106.485	102.540	EPSD	COSMIC	98.777	Down-regulation
CMGC_DYRK_HIPK_HIPK2_ST	Q9P1Z0	ZBTB4	Q9H2X6	HIPK2	S391	P392L	392	Missense	proximal	1	no	106.485	-13.800	EPSD	COSMIC	98.777	Loss
CMGC_DYRK_HIPK_HIPK2_ST	Q9P1Z0	ZBTB4	Q9H2X6	HIPK2	S391	P392Q	392	Missense	proximal	1	no	106.485	54.390	EPSD	COSMIC	98.777	Loss
CMGC_DYRK_HIPK_HIPK2_ST	Q9P1Z0	ZBTB4	Q9H2X6	HIPK2	T532	P533S	533	Missense	proximal	1	no	110.621	93.341	EPSD	COSMIC	98.777	Loss
CMGC_DYRK_HIPK_HIPK2_ST	Q9P1Z0	ZBTB4	Q9H2X6	HIPK2	T532	P525S	525	Missense	distal	-7	no	110.621	109.970	EPSD	COSMIC	98.777	Down-regulation
CMGC_DYRK_HIPK_HIPK2_ST	Q9P1Z0	ZBTB4	Q9H2X6	HIPK2	T532	A530V	530	Missense	proximal	-2	no	110.621	110.263	EPSD	COSMIC	98.777	Down-regulation
CMGC_DYRK_HIPK_HIPK2_ST	Q9P1Z0	ZBTB4	Q9H2X6	HIPK2	T532	A531V	531	Missense	proximal	-1	no	110.621	110.222	EPSD	COSMIC	98.777	Down-regulation
CMGC_DYRK_HIPK_HIPK2_ST	Q9P1Z0	ZBTB4	Q9H2X6	HIPK2	T534	P533S	533	Missense	proximal	-1	no	98.556	98.873	EPSD	COSMIC	98.777	Gain
CMGC_DYRK_HIPK_HIPK2_ST	Q9P1Z0	ZBTB4	Q9H2X6	HIPK2	T534	A531V	531	Missense	distal	-3	no	98.556	98.780	EPSD	COSMIC	98.777	Gain
CMGC_DYRK_HIPK_HIPK2_ST	Q9P1Z0	ZBTB4	Q9H2X6	HIPK2	S535	P533S	533	Missense	proximal	-2	no	103.313	103.388	EPSD	COSMIC	98.777	Up-regulation
CMGC_DYRK_HIPK_HIPK2_ST	Q9P1Z0	ZBTB4	Q9H2X6	HIPK2	S535	A530V	530	Missense	distal	-5	no	103.313	105.859	EPSD	COSMIC	98.777	Up-regulation
CMGC_DYRK_HIPK_HIPK2_ST	Q9P1Z0	ZBTB4	Q9H2X6	HIPK2	S535	A531V	531	Missense	distal	-4	no	103.313	103.031	EPSD	COSMIC	98.777	Down-regulation
CMGC_DYRK_HIPK_HIPK2_ST	Q9P1Z0	ZBTB4	Q9H2X6	HIPK2	T710	R704Q	704	Missense	distal	-6	no	114.402	114.766	EPSD	COSMIC	98.777	Up-regulation
CMGC_DYRK_HIPK_HIPK2_ST	Q9P1Z0	ZBTB4	Q9H2X6	HIPK2	T795	G793E	793	Missense	proximal	-2	no	114.414	114.321	EPSD;PhosphoSitePlus	COSMIC	98.777	Down-regulation
CMGC_DYRK_HIPK_HIPK2_ST	Q9P1Z0	ZBTB4	Q9H2X6	HIPK2	T797	G793E	793	Missense	distal	-4	no	115.078	115.191	PhosphoSitePlus;EPSD	COSMIC	98.777	Up-regulation
CMGC_DYRK_HIPK_HIPK2_ST	Q9P1Z0	ZBTB4	Q9H2X6	HIPK2	T983	P981A	981	Missense	proximal	-2	no	119.447	119.379	EPSD;PhosphoSitePlus	COSMIC	98.777	Down-regulation
CMGC_DYRK_HIPK_HIPK2_ST	Q9P1Z0	ZBTB4	Q9H2X6	HIPK2	T983	P982S	982	Missense	proximal	-1	no	119.447	119.764	EPSD;PhosphoSitePlus	COSMIC	98.777	Up-regulation
CMGC_DYRK_HIPK_HIPK2_ST	Q01196	RUNX1	Q9H2X6	HIPK2	T14	T14M	14	Missense	central	0	yes	109.190	0.000	EPSD	COSMIC	98.777	Loss
CMGC_DYRK_HIPK_HIPK2_ST	Q01196	RUNX1	Q9H2X6	HIPK2	S21	K24N	24	Missense	distal	3	no	108.003	107.915	EPSD	COSMIC	98.777	Down-regulation
CMGC_DYRK_HIPK_HIPK2_ST	Q01196	RUNX1	Q9H2X6	HIPK2	S21	M25K	25	Missense	distal	4	no	108.003	110.394	EPSD	COSMIC	98.777	Up-regulation
CMGC_DYRK_HIPK_HIPK2_ST	Q01196	RUNX1	Q9H2X6	HIPK2	S21	E27Q	27	Missense	distal	6	no	108.003	107.733	EPSD	COSMIC	98.777	Down-regulation
CMGC_DYRK_HIPK_HIPK2_ST	Q01196	RUNX1	Q9H2X6	HIPK2	S21	A28E	28	Missense	distal	7	no	108.003	108.195	EPSD	COSMIC	98.777	Up-regulation
CMGC_DYRK_HIPK_HIPK2_ST	Q01196	RUNX1	Q9H2X6	HIPK2	S21	P22L	22	Missense	proximal	1	no	108.003	-12.282	EPSD	COSMIC;CCLE	98.777	Loss
CMGC_DYRK_HIPK_HIPK2_ST	Q01196	RUNX1	Q9H2X6	HIPK2	S21	P22Q	22	Missense	proximal	1	no	108.003	55.907	EPSD	COSMIC	98.777	Loss
CMGC_DYRK_HIPK_HIPK2_ST	Q01196	RUNX1	Q9H2X6	HIPK2	S21	E27K	27	Missense	distal	6	no	108.003	107.631	EPSD	COSMIC	98.777	Down-regulation
CMGC_DYRK_HIPK_HIPK2_ST	Q01196	RUNX1	Q9H2X6	HIPK2	S21	T14M	14	Missense	distal	-7	no	108.003	107.816	EPSD	COSMIC	98.777	Down-regulation
CMGC_DYRK_HIPK_HIPK2_ST	Q01196	RUNX1	Q9H2X6	HIPK2	S67	L62R	62	Missense	distal	-5	no	93.729	99.371	EPSD	COSMIC	98.777	Gain
CMGC_DYRK_HIPK_HIPK2_ST	Q01196	RUNX1	Q9H2X6	HIPK2	S212	R205Q	205	Missense	distal	-7	no	97.668	98.794	EPSD	COSMIC	98.777	Gain
CMGC_DYRK_HIPK_HIPK2_ST	Q01196	RUNX1	Q9H2X6	HIPK2	S249	T243I	243	Missense	distal	-6	no	118.147	118.414	PhosphoSitePlus;EPSD	COSMIC	98.777	Up-regulation
CMGC_DYRK_HIPK_HIPK2_ST	Q01196	RUNX1	Q9H2X6	HIPK2	S249	P250L	250	Missense	proximal	1	no	118.147	-2.138	PhosphoSitePlus;EPSD	COSMIC	98.777	Loss
CMGC_DYRK_HIPK_HIPK2_ST	Q01196	RUNX1	Q9H2X6	HIPK2	S249	P251L	251	Missense	proximal	2	no	118.147	116.597	PhosphoSitePlus;EPSD	COSMIC	98.777	Down-regulation
CMGC_DYRK_HIPK_HIPK2_ST	Q01196	RUNX1	Q9H2X6	HIPK2	S249	T243K	243	Missense	distal	-6	no	118.147	118.503	PhosphoSitePlus;EPSD	COSMIC	98.777	Up-regulation
CMGC_DYRK_HIPK_HIPK2_ST	Q01196	RUNX1	Q9H2X6	HIPK2	S266	S268F	268	Missense	proximal	2	no	102.931	100.040	EPSD	COSMIC	98.777	Down-regulation
CMGC_DYRK_HIPK_HIPK2_ST	Q01196	RUNX1	Q9H2X6	HIPK2	S266	P267S	267	Missense	proximal	1	no	102.931	85.651	EPSD	COSMIC	98.777	Loss
CMGC_DYRK_HIPK_HIPK2_ST	Q01196	RUNX1	Q9H2X6	HIPK2	S266	T273M	273	Missense	distal	7	no	102.931	102.525	EPSD	COSMIC	98.777	Down-regulation
CMGC_DYRK_HIPK_HIPK2_ST	Q01196	RUNX1	Q9H2X6	HIPK2	S266	G262R	262	Missense	distal	-4	no	102.931	102.887	EPSD	COSMIC	98.777	Down-regulation
CMGC_DYRK_HIPK_HIPK2_ST	Q01196	RUNX1	Q9H2X6	HIPK2	S266	P271Q	271	Missense	distal	5	no	102.931	102.906	EPSD	COSMIC	98.777	Down-regulation
CMGC_DYRK_HIPK_HIPK2_ST	Q01196	RUNX1	Q9H2X6	HIPK2	S266	Y260F	260	Missense	distal	-6	no	102.931	103.046	EPSD	COSMIC	98.777	Up-regulation
CMGC_DYRK_HIPK_HIPK2_ST	Q01196	RUNX1	Q9H2X6	HIPK2	S266	P271S	271	Missense	distal	5	no	102.931	102.932	EPSD	COSMIC	98.777	Up-regulation
CMGC_DYRK_HIPK_HIPK2_ST	Q01196	RUNX1	Q9H2X6	HIPK2	S266	A265S	265	Missense	proximal	-1	no	102.931	104.006	EPSD	COSMIC	98.777	Up-regulation
CMGC_DYRK_HIPK_HIPK2_ST	Q01196	RUNX1	Q9H2X6	HIPK2	S266	L261P	261	Missense	distal	-5	no	102.931	110.355	EPSD	COSMIC	98.777	Up-regulation
CMGC_DYRK_HIPK_HIPK2_ST	Q01196	RUNX1	Q9H2X6	HIPK2	S266	A272G	272	Missense	distal	6	no	102.931	102.670	EPSD	COSMIC	98.777	Down-regulation
CMGC_DYRK_HIPK_HIPK2_ST	Q01196	RUNX1	Q9H2X6	HIPK2	T273	P277L	277	Missense	distal	4	no	122.509	121.509	EPSD;PhosphoSitePlus	COSMIC	98.777	Down-regulation
CMGC_DYRK_HIPK_HIPK2_ST	Q01196	RUNX1	Q9H2X6	HIPK2	T273	S268F	268	Missense	distal	-5	no	122.509	121.192	EPSD;PhosphoSitePlus	COSMIC	98.777	Down-regulation
CMGC_DYRK_HIPK_HIPK2_ST	Q01196	RUNX1	Q9H2X6	HIPK2	T273	P267S	267	Missense	distal	-6	no	122.509	122.516	EPSD;PhosphoSitePlus	COSMIC	98.777	Up-regulation
CMGC_DYRK_HIPK_HIPK2_ST	Q01196	RUNX1	Q9H2X6	HIPK2	T273	S276L	276	Missense	distal	3	no	122.509	121.974	EPSD;PhosphoSitePlus	COSMIC	98.777	Down-regulation
CMGC_DYRK_HIPK_HIPK2_ST	Q01196	RUNX1	Q9H2X6	HIPK2	T273	T273M	273	Missense	central	0	yes	122.509	0.000	EPSD;PhosphoSitePlus	COSMIC	98.777	Loss
CMGC_DYRK_HIPK_HIPK2_ST	Q01196	RUNX1	Q9H2X6	HIPK2	T273	P271Q	271	Missense	proximal	-2	no	122.509	122.561	EPSD;PhosphoSitePlus	COSMIC	98.777	Up-regulation
CMGC_DYRK_HIPK_HIPK2_ST	Q01196	RUNX1	Q9H2X6	HIPK2	T273	P271S	271	Missense	proximal	-2	no	122.509	122.585	EPSD;PhosphoSitePlus	COSMIC	98.777	Up-regulation
CMGC_DYRK_HIPK_HIPK2_ST	Q01196	RUNX1	Q9H2X6	HIPK2	T273	R279C	279	Missense	distal	6	no	122.509	122.041	EPSD;PhosphoSitePlus	COSMIC	98.777	Down-regulation
CMGC_DYRK_HIPK_HIPK2_ST	Q01196	RUNX1	Q9H2X6	HIPK2	T273	A272G	272	Missense	proximal	-1	no	122.509	122.954	EPSD;PhosphoSitePlus	COSMIC	98.777	Up-regulation
CMGC_DYRK_HIPK_HIPK2_ST	Q01196	RUNX1	Q9H2X6	HIPK2	T273	R279P	279	Missense	distal	6	no	122.509	123.039	EPSD;PhosphoSitePlus	COSMIC	98.777	Up-regulation
CMGC_DYRK_HIPK_HIPK2_ST	Q01196	RUNX1	Q9H2X6	HIPK2	S276	P277L	277	Missense	proximal	1	no	119.422	-0.863	EPSD;PhosphoSitePlus	COSMIC	98.777	Loss
CMGC_DYRK_HIPK_HIPK2_ST	Q01196	RUNX1	Q9H2X6	HIPK2	S276	S276L	276	Missense	central	0	yes	119.422	0.000	EPSD;PhosphoSitePlus	COSMIC	98.777	Loss
CMGC_DYRK_HIPK_HIPK2_ST	Q01196	RUNX1	Q9H2X6	HIPK2	S276	T273M	273	Missense	distal	-3	no	119.422	119.227	EPSD;PhosphoSitePlus	COSMIC	98.777	Down-regulation
CMGC_DYRK_HIPK_HIPK2_ST	Q01196	RUNX1	Q9H2X6	HIPK2	S276	G282S	282	Missense	distal	6	no	119.422	119.650	EPSD;PhosphoSitePlus	COSMIC	98.777	Up-regulation
CMGC_DYRK_HIPK_HIPK2_ST	Q01196	RUNX1	Q9H2X6	HIPK2	S276	P271Q	271	Missense	distal	-5	no	119.422	117.046	EPSD;PhosphoSitePlus	COSMIC	98.777	Down-regulation
CMGC_DYRK_HIPK_HIPK2_ST	Q01196	RUNX1	Q9H2X6	HIPK2	S276	P271S	271	Missense	distal	-5	no	119.422	115.159	EPSD;PhosphoSitePlus	COSMIC	98.777	Down-regulation
CMGC_DYRK_HIPK_HIPK2_ST	Q01196	RUNX1	Q9H2X6	HIPK2	S276	R279C	279	Missense	distal	3	no	119.422	118.242	EPSD;PhosphoSitePlus	COSMIC	98.777	Down-regulation
CMGC_DYRK_HIPK_HIPK2_ST	Q01196	RUNX1	Q9H2X6	HIPK2	S276	A272G	272	Missense	distal	-4	no	119.422	119.307	EPSD;PhosphoSitePlus	COSMIC	98.777	Down-regulation
CMGC_DYRK_HIPK_HIPK2_ST	Q01196	RUNX1	Q9H2X6	HIPK2	S276	R279P	279	Missense	distal	3	no	119.422	119.500	EPSD;PhosphoSitePlus	COSMIC	98.777	Up-regulation
CMGC_DYRK_HIPK_HIPK2_ST	Q01196	RUNX1	Q9H2X6	HIPK2	S281	P277L	277	Missense	distal	-4	no	103.758	103.621	EPSD	COSMIC	98.777	Down-regulation
CMGC_DYRK_HIPK_HIPK2_ST	Q01196	RUNX1	Q9H2X6	HIPK2	S281	T284M	284	Missense	distal	3	no	103.758	103.703	EPSD	COSMIC	98.777	Down-regulation
CMGC_DYRK_HIPK_HIPK2_ST	Q01196	RUNX1	Q9H2X6	HIPK2	S281	S287F	287	Missense	distal	6	no	103.758	103.276	EPSD	COSMIC	98.777	Down-regulation
CMGC_DYRK_HIPK_HIPK2_ST	Q01196	RUNX1	Q9H2X6	HIPK2	S281	S276L	276	Missense	distal	-5	no	103.758	100.597	EPSD	COSMIC	98.777	Down-regulation
CMGC_DYRK_HIPK_HIPK2_ST	Q01196	RUNX1	Q9H2X6	HIPK2	S281	G282S	282	Missense	proximal	1	no	103.758	97.611	EPSD	COSMIC	98.777	Loss
CMGC_DYRK_HIPK_HIPK2_ST	Q01196	RUNX1	Q9H2X6	HIPK2	S281	A288V	288	Missense	distal	7	no	103.758	103.431	EPSD	COSMIC	98.777	Down-regulation
CMGC_DYRK_HIPK_HIPK2_ST	Q01196	RUNX1	Q9H2X6	HIPK2	S281	R279C	279	Missense	proximal	-2	no	103.758	103.059	EPSD	COSMIC	98.777	Down-regulation
CMGC_DYRK_HIPK_HIPK2_ST	Q01196	RUNX1	Q9H2X6	HIPK2	S281	R279P	279	Missense	proximal	-2	no	103.758	104.004	EPSD	COSMIC	98.777	Up-regulation
CMGC_DYRK_HIPK_HIPK2_ST	Q01196	RUNX1	Q9H2X6	HIPK2	S292	P298S	298	Missense	distal	6	no	99.133	99.044	EPSD	COSMIC	98.777	Down-regulation
CMGC_DYRK_HIPK_HIPK2_ST	Q01196	RUNX1	Q9H2X6	HIPK2	S292	E289K	289	Missense	distal	-3	no	99.133	99.132	EPSD	COSMIC	98.777	Down-regulation
CMGC_DYRK_HIPK_HIPK2_ST	Q01196	RUNX1	Q9H2X6	HIPK2	S292	S287F	287	Missense	distal	-5	no	99.133	97.816	EPSD	COSMIC	98.777	Loss
CMGC_DYRK_HIPK_HIPK2_ST	Q01196	RUNX1	Q9H2X6	HIPK2	S292	S291A	291	Missense	proximal	-1	no	99.133	98.058	EPSD	COSMIC	98.777	Loss
CMGC_DYRK_HIPK_HIPK2_ST	Q01196	RUNX1	Q9H2X6	HIPK2	S292	A288V	288	Missense	distal	-4	no	99.133	98.851	EPSD	COSMIC	98.777	Down-regulation
CMGC_DYRK_HIPK_HIPK2_ST	Q01196	RUNX1	Q9H2X6	HIPK2	S292	D299N	299	Missense	distal	7	no	99.133	99.168	EPSD	COSMIC	98.777	Up-regulation
CMGC_DYRK_HIPK_HIPK2_ST	Q01196	RUNX1	Q9H2X6	HIPK2	S292	L294P	294	Missense	proximal	2	no	99.133	100.682	EPSD	COSMIC	98.777	Up-regulation
CMGC_DYRK_HIPK_HIPK2_ST	Q01196	RUNX1	Q9H2X6	HIPK2	S292	T296M	296	Missense	distal	4	no	99.133	98.941	EPSD	COSMIC	98.777	Down-regulation
CMGC_DYRK_HIPK_HIPK2_ST	Q01196	RUNX1	Q9H2X6	HIPK2	S292	L290F	290	Missense	proximal	-2	no	99.133	98.794	EPSD	COSMIC	98.777	Down-regulation
CMGC_DYRK_HIPK_HIPK2_ST	Q01196	RUNX1	Q9H2X6	HIPK2	S292	A297V	297	Missense	distal	5	no	99.133	99.231	EPSD	COSMIC	98.777	Up-regulation
CMGC_DYRK_HIPK_HIPK2_ST	Q01196	RUNX1	Q9H2X6	HIPK2	S329	F326S	326	Missense	distal	-3	no	98.870	98.152	EPSD	COSMIC	98.777	Loss
CMGC_DYRK_HIPK_HIPK2_ST	Q01196	RUNX1	Q9H2X6	HIPK2	S329	P323S	323	Missense	distal	-6	no	98.870	98.876	EPSD	COSMIC	98.777	Up-regulation
CMGC_DYRK_HIPK_HIPK2_ST	Q01196	RUNX1	Q9H2X6	HIPK2	S329	P332L	332	Missense	distal	3	no	98.870	98.646	EPSD	COSMIC	98.777	Loss
CMGC_DYRK_HIPK_HIPK2_ST	Q01196	RUNX1	Q9H2X6	HIPK2	S329	S335L	335	Missense	distal	6	no	98.870	98.586	EPSD	COSMIC	98.777	Loss
CMGC_DYRK_HIPK_HIPK2_ST	Q01196	RUNX1	Q9H2X6	HIPK2	T331	F326S	326	Missense	distal	-5	no	104.491	105.808	EPSD	COSMIC	98.777	Up-regulation
CMGC_DYRK_HIPK_HIPK2_ST	Q01196	RUNX1	Q9H2X6	HIPK2	T331	G338V	338	Missense	distal	7	no	104.491	104.460	EPSD	COSMIC	98.777	Down-regulation
CMGC_DYRK_HIPK_HIPK2_ST	Q01196	RUNX1	Q9H2X6	HIPK2	T331	P332L	332	Missense	proximal	1	no	104.491	-15.794	EPSD	COSMIC	98.777	Loss
CMGC_DYRK_HIPK_HIPK2_ST	Q01196	RUNX1	Q9H2X6	HIPK2	T331	S335L	335	Missense	distal	4	no	104.491	102.358	EPSD	COSMIC	98.777	Down-regulation
CMGC_DYRK_HIPK_HIPK2_ST	Q01196	RUNX1	Q9H2X6	HIPK2	S373	G367D	367	Missense	distal	-6	no	113.156	113.270	EPSD	COSMIC	98.777	Up-regulation
CMGC_DYRK_HIPK_HIPK2_ST	Q01196	RUNX1	Q9H2X6	HIPK2	S373	S373L	373	Missense	central	0	yes	113.156	0.000	EPSD	COSMIC	98.777	Loss
CMGC_DYRK_HIPK_HIPK2_ST	Q01196	RUNX1	Q9H2X6	HIPK2	S373	Q370R	370	Missense	distal	-3	no	113.156	113.721	EPSD	COSMIC	98.777	Up-regulation
CMGC_DYRK_HIPK_HIPK2_ST	Q01196	RUNX1	Q9H2X6	HIPK2	S373	P368M	368	Missense	distal	-5	no	113.156	104.712	EPSD	COSMIC	98.777	Down-regulation
CMGC_DYRK_HIPK_HIPK2_ST	Q01196	RUNX1	Q9H2X6	HIPK2	S373	Y380C	380	Missense	distal	7	no	113.156	112.751	EPSD	COSMIC	98.777	Down-regulation
CMGC_DYRK_HIPK_HIPK2_ST	Q01196	RUNX1	Q9H2X6	HIPK2	S373	S375F	375	Missense	proximal	2	no	113.156	110.265	EPSD	COSMIC	98.777	Down-regulation
CMGC_DYRK_HIPK_HIPK2_ST	Q01196	RUNX1	Q9H2X6	HIPK2	S373	G366A	366	Missense	distal	-7	no	113.156	113.699	EPSD	COSMIC	98.777	Up-regulation
CMGC_DYRK_HIPK_HIPK2_ST	Q01196	RUNX1	Q9H2X6	HIPK2	S373	F369I	369	Missense	distal	-4	no	113.156	113.256	EPSD	COSMIC	98.777	Up-regulation
CMGC_DYRK_HIPK_HIPK2_ST	Q01196	RUNX1	Q9H2X6	HIPK2	S373	P368L	368	Missense	distal	-5	no	113.156	105.733	EPSD	COSMIC	98.777	Down-regulation
CMGC_DYRK_HIPK_HIPK2_ST	Q01196	RUNX1	Q9H2X6	HIPK2	S435	E429D	429	Missense	distal	-6	no	98.927	98.919	EPSD	COSMIC	98.777	Down-regulation
CMGC_DYRK_HIPK_HIPK2_ST	Q01196	RUNX1	Q9H2X6	HIPK2	S435	A440V	440	Missense	distal	5	no	98.927	99.025	EPSD	COSMIC	98.777	Up-regulation
CMGC_DYRK_HIPK_HIPK2_ST	Q01196	RUNX1	Q9H2X6	HIPK2	S435	S433N	433	Missense	proximal	-2	no	98.927	98.670	EPSD	COSMIC	98.777	Loss
CMGC_DYRK_HIPK_HIPK2_ST	Q01196	RUNX1	Q9H2X6	HIPK2	S435	P436C	436	Missense	proximal	1	no	98.927	-29.592	EPSD	COSMIC	98.777	Loss
CMGC_DYRK_HIPK_HIPK2_ST	Q01196	RUNX1	Q9H2X6	HIPK2	S435	S442F	442	Missense	distal	7	no	98.927	98.368	EPSD	COSMIC	98.777	Loss
CMGC_DYRK_HIPK_HIPK2_ST	Q01196	RUNX1	Q9H2X6	HIPK2	S435	E429K	429	Missense	distal	-6	no	98.927	99.018	EPSD	COSMIC	98.777	Up-regulation
CMGC_DYRK_HIPK_HIPK2_ST	Q01196	RUNX1	Q9H2X6	HIPK2	S435	S431G	431	Missense	distal	-4	no	98.927	98.846	EPSD	COSMIC	98.777	Down-regulation
CMGC_DYRK_HIPK_HIPK2_ST	Q01196	RUNX1	Q9H2X6	HIPK2	S435	M439L	439	Missense	distal	4	no	98.927	98.743	EPSD	COSMIC;CCLE	98.777	Loss
CMGC_DYRK_HIPK_HIPK2_ST	Q01196	RUNX1	Q9H2X6	HIPK2	S435	M439T	439	Missense	distal	4	no	98.927	99.118	EPSD	COSMIC	98.777	Up-regulation
CMGC_DYRK_HIPK_HIPK2_ST	P57682	KLF3	Q9H2X6	HIPK2	T49	T49A	49	Missense	central	0	yes	117.825	0.000	EPSD	COSMIC	98.777	Loss
CMGC_DYRK_HIPK_HIPK2_ST	P57682	KLF3	Q9H2X6	HIPK2	S71	L64P	64	Missense	distal	-7	no	114.441	115.527	EPSD;PhosphoSitePlus	COSMIC	98.777	Up-regulation
CMGC_DYRK_HIPK_HIPK2_ST	P57682	KLF3	Q9H2X6	HIPK2	S71	S78L	78	Missense	distal	7	no	114.441	114.223	EPSD;PhosphoSitePlus	COSMIC;GDSC;CCLE	98.777	Down-regulation
CMGC_DYRK_HIPK_HIPK2_ST	P57682	KLF3	Q9H2X6	HIPK2	S71	L64I	64	Missense	distal	-7	no	114.441	114.633	EPSD;PhosphoSitePlus	COSMIC;CCLE	98.777	Up-regulation
CMGC_DYRK_HIPK_HIPK2_ST	P57682	KLF3	Q9H2X6	HIPK2	S78	S78L	78	Missense	central	0	yes	118.243	0.000	PhosphoSitePlus;EPSD	COSMIC;GDSC;CCLE	98.777	Loss
CMGC_DYRK_HIPK_HIPK2_ST	P57682	KLF3	Q9H2X6	HIPK2	S92	M97I	97	Missense	distal	5	no	114.986	114.824	EPSD;PhosphoSitePlus	COSMIC	98.777	Down-regulation
CMGC_DYRK_HIPK_HIPK2_ST	P57682	KLF3	Q9H2X6	HIPK2	S92	S99C	99	Missense	distal	7	no	114.986	114.059	EPSD;PhosphoSitePlus	COSMIC	98.777	Down-regulation
CMGC_DYRK_HIPK_HIPK2_ST	P57682	KLF3	Q9H2X6	HIPK2	S101	M97I	97	Missense	distal	-4	no	121.389	121.566	EPSD;PhosphoSitePlus	COSMIC	98.777	Up-regulation
CMGC_DYRK_HIPK_HIPK2_ST	P57682	KLF3	Q9H2X6	HIPK2	S101	S99C	99	Missense	proximal	-2	no	121.389	120.368	EPSD;PhosphoSitePlus	COSMIC	98.777	Down-regulation
CMGC_DYRK_HIPK_HIPK2_ST	P57682	KLF3	Q9H2X6	HIPK2	S101	K105N	105	Missense	distal	4	no	121.389	118.259	EPSD;PhosphoSitePlus	COSMIC	98.777	Down-regulation
CMGC_DYRK_HIPK_HIPK2_ST	P57682	KLF3	Q9H2X6	HIPK2	S108	V114M	114	Missense	distal	6	no	116.929	116.903	EPSD;PhosphoSitePlus	COSMIC	98.777	Down-regulation
CMGC_DYRK_HIPK_HIPK2_ST	P57682	KLF3	Q9H2X6	HIPK2	S108	K105N	105	Missense	distal	-3	no	116.929	117.299	EPSD;PhosphoSitePlus	COSMIC	98.777	Up-regulation
CMGC_DYRK_HIPK_HIPK2_ST	P57682	KLF3	Q9H2X6	HIPK2	S111	V114M	114	Missense	distal	3	no	116.718	116.663	EPSD;PhosphoSitePlus	COSMIC	98.777	Down-regulation
CMGC_DYRK_HIPK_HIPK2_ST	P57682	KLF3	Q9H2X6	HIPK2	S111	P116H	116	Missense	distal	5	no	116.718	116.969	EPSD;PhosphoSitePlus	COSMIC	98.777	Up-regulation
CMGC_DYRK_HIPK_HIPK2_ST	P57682	KLF3	Q9H2X6	HIPK2	S111	K105N	105	Missense	distal	-6	no	116.718	116.539	EPSD;PhosphoSitePlus	COSMIC	98.777	Down-regulation
CMGC_DYRK_HIPK_HIPK2_ST	P57682	KLF3	Q9H2X6	HIPK2	S216	E213Q	213	Missense	distal	-3	no	117.302	117.144	EPSD;PhosphoSitePlus	COSMIC;GDSC;CCLE	98.777	Down-regulation
CMGC_DYRK_HIPK_HIPK2_ST	P57682	KLF3	Q9H2X6	HIPK2	S216	P218S	218	Missense	proximal	2	no	117.302	117.267	EPSD;PhosphoSitePlus	COSMIC	98.777	Down-regulation
CMGC_DYRK_HIPK_HIPK2_ST	P57682	KLF3	Q9H2X6	HIPK2	S224	L230S	230	Missense	distal	6	no	114.033	114.317	EPSD;PhosphoSitePlus	COSMIC	98.777	Up-regulation
CMGC_DYRK_HIPK_HIPK2_ST	P57682	KLF3	Q9H2X6	HIPK2	S224	P218S	218	Missense	distal	-6	no	114.033	114.039	EPSD;PhosphoSitePlus	COSMIC	98.777	Up-regulation
CMGC_DYRK_HIPK_HIPK2_ST	Q04724	TLE1	Q9H2X6	HIPK2	S285	K280T	280	Missense	distal	-5	no	104.532	99.201	EPSD	COSMIC	98.777	Down-regulation
CMGC_DYRK_HIPK_HIPK2_ST	Q04724	TLE1	Q9H2X6	HIPK2	S286	K280T	280	Missense	distal	-6	no	115.686	115.329	EPSD;PhosphoSitePlus	COSMIC	98.777	Down-regulation
CMGC_DYRK_HIPK_HIPK2_ST	Q04724	TLE1	Q9H2X6	HIPK2	T312	T312M	312	Missense	central	0	yes	106.388	0.000	EPSD	COSMIC	98.777	Loss
CMGC_DYRK_HIPK_HIPK2_ST	Q04724	TLE1	Q9H2X6	HIPK2	T319	T312M	312	Missense	distal	-7	no	111.778	111.591	EPSD	COSMIC	98.777	Down-regulation
CMGC_DYRK_HIPK_HIPK2_ST	Q04724	TLE1	Q9H2X6	HIPK2	T319	P320S	320	Missense	proximal	1	no	111.778	94.498	EPSD	COSMIC;CCLE	98.777	Loss
CMGC_DYRK_HIPK_HIPK2_ST	Q04724	TLE1	Q9H2X6	HIPK2	T321	T328M	328	Missense	distal	7	no	112.012	111.606	EPSD	COSMIC	98.777	Down-regulation
CMGC_DYRK_HIPK_HIPK2_ST	Q04724	TLE1	Q9H2X6	HIPK2	T321	P320S	320	Missense	proximal	-1	no	112.012	112.329	EPSD	COSMIC;CCLE	98.777	Up-regulation
CMGC_DYRK_HIPK_HIPK2_ST	Q04724	TLE1	Q9H2X6	HIPK2	T328	T328M	328	Missense	central	0	yes	118.841	0.000	EPSD	COSMIC	98.777	Loss
CMGC_DYRK_HIPK_HIPK2_ST	Q04724	TLE1	Q9H2X6	HIPK2	T334	T328M	328	Missense	distal	-6	no	116.873	116.855	EPSD	COSMIC	98.777	Down-regulation
CMGC_DYRK_HIPK_HIPK2_ST	Q04724	TLE1	Q9H2X6	HIPK2	T334	L341I	341	Missense	distal	7	no	116.873	116.779	EPSD	COSMIC	98.777	Down-regulation
CMGC_DYRK_HIPK_HIPK2_ST	Q04724	TLE1	Q9H2X6	HIPK2	T334	R338C	338	Missense	distal	4	no	116.873	109.260	EPSD	COSMIC;GDSC;CCLE	98.777	Down-regulation
CMGC_DYRK_HIPK_HIPK2_ST	Q04724	TLE1	Q9H2X6	HIPK2	S416	G414R	414	Missense	proximal	-2	no	106.834	106.485	EPSD	COSMIC	98.777	Down-regulation
CMGC_DYRK_HIPK_HIPK2_ST	Q04724	TLE1	Q9H2X6	HIPK2	S416	M418I	418	Missense	proximal	2	no	106.834	106.693	EPSD	COSMIC	98.777	Down-regulation
CMGC_DYRK_HIPK_HIPK2_ST	Q04724	TLE1	Q9H2X6	HIPK2	S519	C526R	526	Missense	distal	7	no	98.703	99.025	EPSD	COSMIC	98.777	Gain
CMGC_DYRK_HIPK_HIPK2_ST	P17096	HMGA1	Q9H2X6	HIPK2	S36	P37S	37	Missense	proximal	1	no	115.973	98.693	EPSD;PhosphoSitePlus	COSMIC	98.777	Loss
CMGC_DYRK_HIPK_HIPK2_ST	P17096	HMGA1	Q9H2X6	HIPK2	T72	T75I	75	Missense	distal	3	no	106.663	107.114	EPSD	COSMIC	98.777	Up-regulation
CMGC_DYRK_HIPK_HIPK2_ST	P17096	HMGA1	Q9H2X6	HIPK2	T78	T75I	75	Missense	distal	-3	no	121.586	121.299	PhosphoSitePlus;EPSD	COSMIC	98.777	Down-regulation
CMGC_DYRK_HIPK_HIPK2_ST	P46531	NOTCH1	Q9H2X6	HIPK2	T518	T518M	518	Missense	central	0	yes	99.739	0.000	EPSD	COSMIC	98.777	Loss
CMGC_DYRK_HIPK_HIPK2_ST	P46531	NOTCH1	Q9H2X6	HIPK2	T518	F520L	520	Missense	proximal	2	no	99.739	101.117	EPSD	COSMIC	98.777	Up-regulation
CMGC_DYRK_HIPK_HIPK2_ST	P46531	NOTCH1	Q9H2X6	HIPK2	T518	P517T	517	Missense	proximal	-1	no	99.739	98.259	EPSD	COSMIC	98.777	Loss
CMGC_DYRK_HIPK_HIPK2_ST	P46531	NOTCH1	Q9H2X6	HIPK2	T518	P517S	517	Missense	proximal	-1	no	99.739	100.056	EPSD	COSMIC	98.777	Up-regulation
CMGC_DYRK_HIPK_HIPK2_ST	P46531	NOTCH1	Q9H2X6	HIPK2	T518	P517L	517	Missense	proximal	-1	no	99.739	98.349	EPSD	COSMIC	98.777	Loss
CMGC_DYRK_HIPK_HIPK2_ST	P46531	NOTCH1	Q9H2X6	HIPK2	T518	G519S	519	Missense	proximal	1	no	99.739	93.592	EPSD	COSMIC	98.777	Loss
CMGC_DYRK_HIPK_HIPK2_ST	P46531	NOTCH1	Q9H2X6	HIPK2	T518	C514Y	514	Missense	distal	-4	no	99.739	100.051	EPSD	COSMIC	98.777	Up-regulation
CMGC_DYRK_HIPK_HIPK2_ST	P46531	NOTCH1	Q9H2X6	HIPK2	T518	G522R	522	Missense	distal	4	no	99.739	98.060	EPSD	COSMIC	98.777	Loss
CMGC_DYRK_HIPK_HIPK2_ST	P46531	NOTCH1	Q9H2X6	HIPK2	T518	C516R	516	Missense	proximal	-2	no	99.739	100.439	EPSD	COSMIC;CCLE	98.777	Up-regulation
CMGC_DYRK_HIPK_HIPK2_ST	P46531	NOTCH1	Q9H2X6	HIPK2	T1861	E1866K	1866	Missense	distal	5	no	100.189	100.252	EPSD	COSMIC	98.777	Up-regulation
CMGC_DYRK_HIPK_HIPK2_ST	P46531	NOTCH1	Q9H2X6	HIPK2	T1861	M1855V	1855	Missense	distal	-6	no	100.189	100.103	EPSD	COSMIC	98.777	Down-regulation
CMGC_DYRK_HIPK_HIPK2_ST	P46531	NOTCH1	Q9H2X6	HIPK2	T1861	V1867I	1867	Missense	distal	6	no	100.189	100.371	EPSD	COSMIC	98.777	Up-regulation
CMGC_DYRK_HIPK_HIPK2_ST	P46531	NOTCH1	Q9H2X6	HIPK2	T1861	S1856C	1856	Missense	distal	-5	no	100.189	89.019	EPSD	COSMIC	98.777	Loss
CMGC_DYRK_HIPK_HIPK2_ST	P46531	NOTCH1	Q9H2X6	HIPK2	T1861	Q1864R	1864	Missense	distal	3	no	100.189	99.545	EPSD	COSMIC	98.777	Down-regulation
CMGC_DYRK_HIPK_HIPK2_ST	P46531	NOTCH1	Q9H2X6	HIPK2	T1861	M1858L	1858	Missense	distal	-3	no	100.189	100.326	EPSD	COSMIC	98.777	Up-regulation
CMGC_DYRK_HIPK_HIPK2_ST	P46531	NOTCH1	Q9H2X6	HIPK2	T1861	P1860L	1860	Missense	proximal	-1	no	100.189	98.799	EPSD	COSMIC	98.777	Down-regulation
CMGC_DYRK_HIPK_HIPK2_ST	P46531	NOTCH1	Q9H2X6	HIPK2	S1891	M1886I	1886	Missense	distal	-5	no	96.970	102.358	EPSD	COSMIC	98.777	Gain
CMGC_DYRK_HIPK_HIPK2_ST	P46531	NOTCH1	Q9H2X6	HIPK2	T1997	A2002V	2002	Missense	distal	5	no	100.798	100.896	EPSD	COSMIC	98.777	Up-regulation
CMGC_DYRK_HIPK_HIPK2_ST	P46531	NOTCH1	Q9H2X6	HIPK2	T1997	R2004H	2004	Missense	distal	7	no	100.798	100.703	EPSD	COSMIC	98.777	Down-regulation
CMGC_DYRK_HIPK_HIPK2_ST	P46531	NOTCH1	Q9H2X6	HIPK2	S2136	P2133A	2133	Missense	distal	-3	no	104.087	104.123	EPSD	COSMIC	98.777	Up-regulation
CMGC_DYRK_HIPK_HIPK2_ST	P46531	NOTCH1	Q9H2X6	HIPK2	S2136	L2139F	2139	Missense	distal	3	no	104.087	103.874	EPSD	COSMIC	98.777	Down-regulation
CMGC_DYRK_HIPK_HIPK2_ST	P46531	NOTCH1	Q9H2X6	HIPK2	S2136	G2131N	2131	Missense	distal	-5	no	104.087	103.651	EPSD	COSMIC	98.777	Down-regulation
CMGC_DYRK_HIPK_HIPK2_ST	P46531	NOTCH1	Q9H2X6	HIPK2	S2136	T2132M	2132	Missense	distal	-4	no	104.087	103.812	EPSD	COSMIC	98.777	Down-regulation
CMGC_DYRK_HIPK_HIPK2_ST	P46531	NOTCH1	Q9H2X6	HIPK2	S2136	L2139P	2139	Missense	distal	3	no	104.087	104.310	EPSD	COSMIC	98.777	Up-regulation
CMGC_DYRK_HIPK_HIPK2_ST	P46531	NOTCH1	Q9H2X6	HIPK2	S2136	L2129V	2129	Missense	distal	-7	no	104.087	104.384	EPSD	COSMIC	98.777	Up-regulation
CMGC_DYRK_HIPK_HIPK2_ST	P46531	NOTCH1	Q9H2X6	HIPK2	S2136	C2140Y	2140	Missense	distal	4	no	104.087	108.684	EPSD	COSMIC	98.777	Up-regulation
CMGC_DYRK_HIPK_HIPK2_ST	P46531	NOTCH1	Q9H2X6	HIPK2	S2141	L2139F	2139	Missense	proximal	-2	no	104.746	104.408	EPSD	COSMIC	98.777	Down-regulation
CMGC_DYRK_HIPK_HIPK2_ST	P46531	NOTCH1	Q9H2X6	HIPK2	S2141	L2139P	2139	Missense	proximal	-2	no	104.746	105.001	EPSD	COSMIC	98.777	Up-regulation
CMGC_DYRK_HIPK_HIPK2_ST	P46531	NOTCH1	Q9H2X6	HIPK2	S2141	S2148R	2148	Missense	distal	7	no	104.746	104.141	EPSD	COSMIC	98.777	Down-regulation
CMGC_DYRK_HIPK_HIPK2_ST	P46531	NOTCH1	Q9H2X6	HIPK2	S2141	C2140Y	2140	Missense	proximal	-1	no	104.746	106.376	EPSD	COSMIC	98.777	Up-regulation
CMGC_DYRK_HIPK_HIPK2_ST	P46531	NOTCH1	Q9H2X6	HIPK2	S2148	L2149P	2149	Missense	proximal	1	no	-3.668	116.617	EPSD	COSMIC	98.777	Gain
CMGC_DYRK_HIPK_HIPK2_ST	P46531	NOTCH1	Q9H2X6	HIPK2	S2221	S2221F	2221	Missense	central	0	yes	105.935	0.000	EPSD	COSMIC	98.777	Loss
CMGC_DYRK_HIPK_HIPK2_ST	P46531	NOTCH1	Q9H2X6	HIPK2	S2221	S2215L	2215	Missense	distal	-6	no	105.935	105.794	EPSD	COSMIC;GDSC;CCLE	98.777	Down-regulation
CMGC_DYRK_HIPK_HIPK2_ST	P46531	NOTCH1	Q9H2X6	HIPK2	T2511	P2514R	2514	Missense	distal	3	no	124.756	124.678	PhosphoSitePlus	COSMIC	98.777	Down-regulation
CMGC_DYRK_HIPK_HIPK2_ST	P46531	NOTCH1	Q9H2X6	HIPK2	T2511	P2517L	2517	Missense	distal	6	no	124.756	124.383	PhosphoSitePlus	COSMIC	98.777	Down-regulation
CMGC_DYRK_HIPK_HIPK2_ST	P46531	NOTCH1	Q9H2X6	HIPK2	T2511	H2507R	2507	Missense	distal	-4	no	124.756	124.971	PhosphoSitePlus	COSMIC	98.777	Up-regulation
CMGC_DYRK_HIPK_HIPK2_ST	P46531	NOTCH1	Q9H2X6	HIPK2	T2511	H2507Y	2507	Missense	distal	-4	no	124.756	124.904	PhosphoSitePlus	COSMIC	98.777	Up-regulation
CMGC_DYRK_HIPK_HIPK2_ST	P46531	NOTCH1	Q9H2X6	HIPK2	T2511	F2509S	2509	Missense	proximal	-2	no	124.756	125.424	PhosphoSitePlus	COSMIC	98.777	Up-regulation
CMGC_DYRK_HIPK_HIPK2_ST	P46531	NOTCH1	Q9H2X6	HIPK2	T2511	L2510F	2510	Missense	proximal	-1	no	124.756	124.201	PhosphoSitePlus	COSMIC	98.777	Down-regulation
CMGC_DYRK_HIPK_HIPK2_ST	P46531	NOTCH1	Q9H2X6	HIPK2	T2511	P2508A	2508	Missense	distal	-3	no	124.756	124.793	PhosphoSitePlus	COSMIC	98.777	Up-regulation
CMGC_DYRK_HIPK_HIPK2_ST	P46531	NOTCH1	Q9H2X6	HIPK2	T2511	P2514S	2514	Missense	distal	3	no	124.756	125.068	PhosphoSitePlus	COSMIC	98.777	Up-regulation
CMGC_DYRK_HIPK_HIPK2_ST	P46531	NOTCH1	Q9H2X6	HIPK2	T2511	S2516A	2516	Missense	distal	5	no	124.756	124.857	PhosphoSitePlus	COSMIC	98.777	Up-regulation
CMGC_DYRK_HIPK_HIPK2_ST	P46531	NOTCH1	Q9H2X6	HIPK2	T2511	L2510R	2510	Missense	proximal	-1	no	124.756	124.935	PhosphoSitePlus	COSMIC	98.777	Up-regulation
CMGC_DYRK_HIPK_HIPK2_ST	P46531	NOTCH1	Q9H2X6	HIPK2	T2511	S2513F	2513	Missense	proximal	2	no	124.756	121.865	PhosphoSitePlus	COSMIC	98.777	Down-regulation
CMGC_DYRK_HIPK_HIPK2_ST	P46531	NOTCH1	Q9H2X6	HIPK2	T2511	P2514L	2514	Missense	distal	3	no	124.756	124.532	PhosphoSitePlus	COSMIC	98.777	Down-regulation
CMGC_DYRK_HIPK_HIPK2_ST	P46531	NOTCH1	Q9H2X6	HIPK2	T2511	E2515K	2515	Missense	distal	4	no	124.756	125.234	PhosphoSitePlus	COSMIC	98.777	Up-regulation
CMGC_DYRK_HIPK_HIPK2_ST	P46531	NOTCH1	Q9H2X6	HIPK2	T2511	L2510H	2510	Missense	proximal	-1	no	124.756	123.645	PhosphoSitePlus	COSMIC	98.777	Down-regulation
CMGC_DYRK_HIPK_HIPK2_ST	P46531	NOTCH1	Q9H2X6	HIPK2	T2511	E2506K	2506	Missense	distal	-5	no	124.756	122.914	PhosphoSitePlus	COSMIC	98.777	Down-regulation
CMGC_DYRK_HIPK_HIPK2_ST	P46531	NOTCH1	Q9H2X6	HIPK2	S2513	P2514R	2514	Missense	proximal	1	no	119.291	106.755	EPSD	COSMIC	98.777	Down-regulation
CMGC_DYRK_HIPK_HIPK2_ST	P46531	NOTCH1	Q9H2X6	HIPK2	S2513	P2517L	2517	Missense	distal	4	no	119.291	118.291	EPSD	COSMIC	98.777	Down-regulation
CMGC_DYRK_HIPK_HIPK2_ST	P46531	NOTCH1	Q9H2X6	HIPK2	S2513	H2507R	2507	Missense	distal	-6	no	119.291	119.588	EPSD	COSMIC	98.777	Up-regulation
CMGC_DYRK_HIPK_HIPK2_ST	P46531	NOTCH1	Q9H2X6	HIPK2	S2513	H2507Y	2507	Missense	distal	-6	no	119.291	119.425	EPSD	COSMIC	98.777	Up-regulation
CMGC_DYRK_HIPK_HIPK2_ST	P46531	NOTCH1	Q9H2X6	HIPK2	S2513	F2509S	2509	Missense	distal	-4	no	119.291	119.485	EPSD	COSMIC	98.777	Up-regulation
CMGC_DYRK_HIPK_HIPK2_ST	P46531	NOTCH1	Q9H2X6	HIPK2	S2513	L2510F	2510	Missense	distal	-3	no	119.291	119.609	EPSD	COSMIC	98.777	Up-regulation
CMGC_DYRK_HIPK_HIPK2_ST	P46531	NOTCH1	Q9H2X6	HIPK2	S2513	P2508A	2508	Missense	distal	-5	no	119.291	110.447	EPSD	COSMIC	98.777	Down-regulation
CMGC_DYRK_HIPK_HIPK2_ST	P46531	NOTCH1	Q9H2X6	HIPK2	S2513	P2514S	2514	Missense	proximal	1	no	119.291	102.011	EPSD	COSMIC	98.777	Down-regulation
CMGC_DYRK_HIPK_HIPK2_ST	P46531	NOTCH1	Q9H2X6	HIPK2	S2513	S2516A	2516	Missense	distal	3	no	119.291	118.542	EPSD	COSMIC	98.777	Down-regulation
CMGC_DYRK_HIPK_HIPK2_ST	P46531	NOTCH1	Q9H2X6	HIPK2	S2513	L2510R	2510	Missense	distal	-3	no	119.291	119.222	EPSD	COSMIC	98.777	Down-regulation
CMGC_DYRK_HIPK_HIPK2_ST	P46531	NOTCH1	Q9H2X6	HIPK2	S2513	S2513F	2513	Missense	central	0	yes	119.291	0.000	EPSD	COSMIC	98.777	Loss
CMGC_DYRK_HIPK_HIPK2_ST	P46531	NOTCH1	Q9H2X6	HIPK2	S2513	P2514L	2514	Missense	proximal	1	no	119.291	-0.994	EPSD	COSMIC	98.777	Loss
CMGC_DYRK_HIPK_HIPK2_ST	P46531	NOTCH1	Q9H2X6	HIPK2	S2513	E2515K	2515	Missense	proximal	2	no	119.291	118.252	EPSD	COSMIC	98.777	Down-regulation
CMGC_DYRK_HIPK_HIPK2_ST	P46531	NOTCH1	Q9H2X6	HIPK2	S2513	L2510H	2510	Missense	distal	-3	no	119.291	119.815	EPSD	COSMIC	98.777	Up-regulation
CMGC_DYRK_HIPK_HIPK2_ST	P46531	NOTCH1	Q9H2X6	HIPK2	S2513	E2506K	2506	Missense	distal	-7	no	119.291	119.474	EPSD	COSMIC	98.777	Up-regulation
CMGC_DYRK_HIPK_HIPK2_ST	P46531	NOTCH1	Q9H2X6	HIPK2	S2522	H2526Q	2526	Missense	distal	4	no	92.449	99.851	EPSD	COSMIC	98.777	Gain
CMGC_DYRK_HIPK_HIPK2_ST	P46531	NOTCH1	Q9H2X6	HIPK2	S2523	P2525L	2525	Missense	proximal	2	no	102.633	101.084	EPSD	COSMIC	98.777	Down-regulation
CMGC_DYRK_HIPK_HIPK2_ST	P46531	NOTCH1	Q9H2X6	HIPK2	S2523	P2517L	2517	Missense	distal	-6	no	102.633	102.498	EPSD	COSMIC	98.777	Down-regulation
CMGC_DYRK_HIPK_HIPK2_ST	P46531	NOTCH1	Q9H2X6	HIPK2	S2523	S2530C	2530	Missense	distal	7	no	102.633	101.707	EPSD	COSMIC	98.777	Down-regulation
CMGC_DYRK_HIPK_HIPK2_ST	P46531	NOTCH1	Q9H2X6	HIPK2	S2523	S2516A	2516	Missense	distal	-7	no	102.633	103.504	EPSD	COSMIC	98.777	Up-regulation
CMGC_DYRK_HIPK_HIPK2_ST	P46531	NOTCH1	Q9H2X6	HIPK2	S2523	P2525S	2525	Missense	proximal	2	no	102.633	102.598	EPSD	COSMIC	98.777	Down-regulation
CMGC_DYRK_HIPK_HIPK2_ST	P46531	NOTCH1	Q9H2X6	HIPK2	S2523	V2529I	2529	Missense	distal	6	no	102.633	102.816	EPSD	COSMIC	98.777	Up-regulation
CMGC_DYRK_HIPK_HIPK2_ST	P46531	NOTCH1	Q9H2X6	HIPK2	S2523	H2526Q	2526	Missense	distal	3	no	102.633	103.765	EPSD	COSMIC	98.777	Up-regulation
CMGC_DYRK_HIPK_HIPK2_ST	P46531	NOTCH1	Q9H2X6	HIPK2	S2523	H2526N	2526	Missense	distal	3	no	102.633	103.057	EPSD	COSMIC	98.777	Up-regulation
CMGC_DYRK_HIPK_HIPK2_ST	P46531	NOTCH1	Q9H2X6	HIPK2	S2523	H2526R	2526	Missense	distal	3	no	102.633	103.121	EPSD	COSMIC	98.777	Up-regulation
CMGC_DYRK_HIPK_HIPK2_ST	P46531	NOTCH1	Q9H2X6	HIPK2	S2524	P2525L	2525	Missense	proximal	1	no	104.924	-15.361	EPSD	COSMIC	98.777	Loss
CMGC_DYRK_HIPK_HIPK2_ST	P46531	NOTCH1	Q9H2X6	HIPK2	S2524	P2517L	2517	Missense	distal	-7	no	104.924	103.837	EPSD	COSMIC	98.777	Down-regulation
CMGC_DYRK_HIPK_HIPK2_ST	P46531	NOTCH1	Q9H2X6	HIPK2	S2524	S2530C	2530	Missense	distal	6	no	104.924	104.015	EPSD	COSMIC	98.777	Down-regulation
CMGC_DYRK_HIPK_HIPK2_ST	P46531	NOTCH1	Q9H2X6	HIPK2	S2524	P2525S	2525	Missense	proximal	1	no	104.924	87.643	EPSD	COSMIC	98.777	Loss
CMGC_DYRK_HIPK_HIPK2_ST	P46531	NOTCH1	Q9H2X6	HIPK2	S2524	V2529I	2529	Missense	distal	5	no	104.924	104.762	EPSD	COSMIC	98.777	Down-regulation
CMGC_DYRK_HIPK_HIPK2_ST	P46531	NOTCH1	Q9H2X6	HIPK2	S2524	H2526Q	2526	Missense	proximal	2	no	104.924	108.175	EPSD	COSMIC	98.777	Up-regulation
CMGC_DYRK_HIPK_HIPK2_ST	P46531	NOTCH1	Q9H2X6	HIPK2	S2524	H2526N	2526	Missense	proximal	2	no	104.924	107.619	EPSD	COSMIC	98.777	Up-regulation
CMGC_DYRK_HIPK_HIPK2_ST	P46531	NOTCH1	Q9H2X6	HIPK2	S2524	H2526R	2526	Missense	proximal	2	no	104.924	105.915	EPSD	COSMIC	98.777	Up-regulation
CMGC_DYRK_HIPK_HIPK2_ST	Q13363	CTBP1	Q9H2X6	HIPK2	S100	D106E	106	Missense	distal	6	no	99.339	99.823	EPSD	COSMIC	98.777	Up-regulation
CMGC_DYRK_HIPK_HIPK2_ST	Q13363	CTBP1	Q9H2X6	HIPK2	S100	D103V	103	Missense	distal	3	no	99.339	99.330	EPSD	COSMIC	98.777	Down-regulation
CMGC_DYRK_HIPK_HIPK2_ST	Q13363	CTBP1	Q9H2X6	HIPK2	S422	H416P	416	Missense	distal	-6	no	114.919	115.361	PhosphoSitePlus	COSMIC	98.777	Up-regulation
CMGC_DYRK_HIPK_HIPK2_ST	Q13363	CTBP1	Q9H2X6	HIPK2	S422	V427I	427	Missense	distal	5	no	114.919	114.757	PhosphoSitePlus	COSMIC;CCLE	98.777	Down-regulation
CMGC_DYRK_HIPK_HIPK2_ST	Q13363	CTBP1	Q9H2X6	HIPK2	S422	V427A	427	Missense	distal	5	no	114.919	114.822	PhosphoSitePlus	COSMIC	98.777	Down-regulation
CMGC_DYRK_HIPK_HIPK2_ST	Q13363	CTBP1	Q9H2X6	HIPK2	S422	T426N	426	Missense	distal	4	no	114.919	113.990	PhosphoSitePlus	COSMIC	98.777	Down-regulation
CMGC_DYRK_HIPK_HIPK2_ST	Q13363	CTBP1	Q9H2X6	HIPK2	S422	H419P	419	Missense	distal	-3	no	114.919	114.176	PhosphoSitePlus	COSMIC	98.777	Down-regulation
CMGC_DYRK_HIPK_HIPK2_ST	Q13363	CTBP1	Q9H2X6	HIPK2	S422	H416Q	416	Missense	distal	-6	no	114.919	115.580	PhosphoSitePlus	COSMIC	98.777	Up-regulation
CMGC_DYRK_HIPK_HIPK2_ST	P56545	CTBP2	Q9H2X6	HIPK2	S106	Y108C	108	Missense	proximal	2	no	100.528	98.459	EPSD	COSMIC	98.777	Loss
CMGC_DYRK_HIPK_HIPK2_ST	P56545	CTBP2	Q9H2X6	HIPK2	S106	R103Q	103	Missense	distal	-3	no	100.528	99.963	EPSD	COSMIC	98.777	Down-regulation
CMGC_DYRK_HIPK_HIPK2_ST	P56545	CTBP2	Q9H2X6	HIPK2	S106	Y108F	108	Missense	proximal	2	no	100.528	99.787	EPSD	COSMIC	98.777	Down-regulation
CMGC_DYRK_HIPK_HIPK2_ST	P56545	CTBP2	Q9H2X6	HIPK2	S428	P423R	423	Missense	distal	-5	no	116.763	114.980	PhosphoSitePlus	COSMIC	98.777	Down-regulation
CMGC_DYRK_HIPK_HIPK2_ST	P56545	CTBP2	Q9H2X6	HIPK2	S428	A421V	421	Missense	distal	-7	no	116.763	115.754	PhosphoSitePlus	COSMIC	98.777	Down-regulation
CMGC_DYRK_HIPK_HIPK2_ST	P29590	PML	Q9H2X6	HIPK2	T28	P26S	26	Missense	proximal	-2	no	101.273	101.349	EPSD	COSMIC	98.777	Up-regulation
CMGC_DYRK_HIPK_HIPK2_ST	P29590	PML	Q9H2X6	HIPK2	S30	P26S	26	Missense	distal	-4	no	113.145	113.012	EPSD	COSMIC	98.777	Down-regulation
CMGC_DYRK_HIPK_HIPK2_ST	P29590	PML	Q9H2X6	HIPK2	S38	R44Q	44	Missense	distal	6	no	115.947	116.430	EPSD;PhosphoSitePlus	COSMIC	98.777	Up-regulation
CMGC_DYRK_HIPK_HIPK2_ST	P29590	PML	Q9H2X6	HIPK2	S40	R44Q	44	Missense	distal	4	no	116.446	118.919	EPSD	COSMIC	98.777	Up-regulation
CMGC_DYRK_HIPK_HIPK2_ST	P29590	PML	Q9H2X6	HIPK2	T42	R44Q	44	Missense	proximal	2	no	102.550	104.810	EPSD	COSMIC	98.777	Up-regulation
CMGC_DYRK_HIPK_HIPK2_ST	P29590	PML	Q9H2X6	HIPK2	T42	E49K	49	Missense	distal	7	no	102.550	102.364	EPSD	COSMIC	98.777	Down-regulation
CMGC_DYRK_HIPK_HIPK2_ST	P29590	PML	Q9H2X6	HIPK2	T482	Q483P	483	Missense	proximal	1	no	61.749	113.844	EPSD	COSMIC	98.777	Gain
CMGC_DYRK_HIPK_HIPK2_ST	P29590	PML	Q9H2X6	HIPK2	S505	P506L	506	Missense	proximal	1	no	102.426	-17.859	EPSD	COSMIC	98.777	Loss
CMGC_DYRK_HIPK_HIPK2_ST	P29590	PML	Q9H2X6	HIPK2	T513	S514P	514	Missense	proximal	1	no	90.417	107.697	EPSD	COSMIC	98.777	Gain
CMGC_DYRK_HIPK_HIPK2_ST	P29590	PML	Q9H2X6	HIPK2	S518	S514P	514	Missense	distal	-4	no	111.531	111.664	EPSD	COSMIC	98.777	Up-regulation
CMGC_DYRK_HIPK_HIPK2_ST	P29590	PML	Q9H2X6	HIPK2	S560	V557G	557	Missense	distal	-3	no	104.125	103.771	EPSD	COSMIC	98.777	Down-regulation
CMGC_DYRK_HIPK_HIPK2_ST	P29590	PML	Q9H2X6	HIPK2	S560	V558L	558	Missense	proximal	-2	no	104.125	104.296	EPSD	COSMIC;GDSC;CCLE	98.777	Up-regulation
CMGC_DYRK_HIPK_HIPK2_ST	P29590	PML	Q9H2X6	HIPK2	S560	I559V	559	Missense	proximal	-1	no	104.125	103.644	EPSD	COSMIC	98.777	Down-regulation
CMGC_DYRK_HIPK_HIPK2_ST	P29590	PML	Q9H2X6	HIPK2	S560	S562P	562	Missense	proximal	2	no	104.125	104.160	EPSD	COSMIC	98.777	Up-regulation
CMGC_DYRK_HIPK_HIPK2_ST	P29590	PML	Q9H2X6	HIPK2	S561	V557G	557	Missense	distal	-4	no	104.036	104.203	EPSD	COSMIC	98.777	Up-regulation
CMGC_DYRK_HIPK_HIPK2_ST	P29590	PML	Q9H2X6	HIPK2	S561	V558L	558	Missense	distal	-3	no	104.036	103.995	EPSD	COSMIC;GDSC;CCLE	98.777	Down-regulation
CMGC_DYRK_HIPK_HIPK2_ST	P29590	PML	Q9H2X6	HIPK2	S561	I559V	559	Missense	proximal	-2	no	104.036	103.686	EPSD	COSMIC	98.777	Down-regulation
CMGC_DYRK_HIPK_HIPK2_ST	P29590	PML	Q9H2X6	HIPK2	S561	S562P	562	Missense	proximal	1	no	104.036	121.316	EPSD	COSMIC	98.777	Up-regulation
CMGC_DYRK_HIPK_HIPK2_ST	P51608	MECP2	Q9H2X6	HIPK2	T64	G60D	60	Missense	distal	-4	no	100.444	100.542	EPSD	COSMIC	98.777	Up-regulation
CMGC_DYRK_HIPK_HIPK2_ST	P51608	MECP2	Q9H2X6	HIPK2	T64	A57T	57	Missense	distal	-7	no	100.444	98.917	EPSD	COSMIC	98.777	Down-regulation
CMGC_DYRK_HIPK_HIPK2_ST	P51608	MECP2	Q9H2X6	HIPK2	T64	A59T	59	Missense	distal	-5	no	100.444	101.016	EPSD	COSMIC	98.777	Up-regulation
CMGC_DYRK_HIPK_HIPK2_ST	P51608	MECP2	Q9H2X6	HIPK2	T64	A71T	71	Missense	distal	7	no	100.444	100.537	EPSD	COSMIC;CCLE	98.777	Up-regulation
CMGC_DYRK_HIPK_HIPK2_ST	P51608	MECP2	Q9H2X6	HIPK2	T64	A62T	62	Missense	proximal	-2	no	100.444	100.225	EPSD	COSMIC	98.777	Down-regulation
CMGC_DYRK_HIPK_HIPK2_ST	P51608	MECP2	Q9H2X6	HIPK2	S65	G60D	60	Missense	distal	-5	no	97.600	100.760	EPSD	COSMIC	98.777	Gain
CMGC_DYRK_HIPK_HIPK2_ST	P51608	MECP2	Q9H2X6	HIPK2	S68	P72L	72	Missense	distal	4	no	104.164	103.164	EPSD	COSMIC	98.777	Down-regulation
CMGC_DYRK_HIPK_HIPK2_ST	P51608	MECP2	Q9H2X6	HIPK2	S68	A71T	71	Missense	distal	3	no	104.164	104.137	EPSD	COSMIC;CCLE	98.777	Down-regulation
CMGC_DYRK_HIPK_HIPK2_ST	P51608	MECP2	Q9H2X6	HIPK2	S68	A62T	62	Missense	distal	-6	no	104.164	104.031	EPSD	COSMIC	98.777	Down-regulation
CMGC_DYRK_HIPK_HIPK2_ST	P51608	MECP2	Q9H2X6	HIPK2	T160	V159I	159	Missense	proximal	-1	no	98.350	98.831	EPSD	COSMIC	98.777	Gain
CMGC_DYRK_HIPK_HIPK2_ST	P51608	MECP2	Q9H2X6	HIPK2	S164	V159I	159	Missense	distal	-5	no	106.321	109.563	EPSD	COSMIC	98.777	Up-regulation
CMGC_DYRK_HIPK_HIPK2_ST	P51608	MECP2	Q9H2X6	HIPK2	S178	P172S	172	Missense	distal	-6	no	113.419	113.425	EPSD	COSMIC	98.777	Up-regulation
CMGC_DYRK_HIPK_HIPK2_ST	P51608	MECP2	Q9H2X6	HIPK2	S178	T184P	184	Missense	distal	6	no	113.419	113.602	EPSD	COSMIC	98.777	Up-regulation
CMGC_DYRK_HIPK_HIPK2_ST	P51608	MECP2	Q9H2X6	HIPK2	S178	P172A	172	Missense	distal	-6	no	113.419	113.285	EPSD	COSMIC	98.777	Down-regulation
CMGC_DYRK_HIPK_HIPK2_ST	P51608	MECP2	Q9H2X6	HIPK2	T184	T184P	184	Missense	central	0	yes	104.632	0.000	EPSD	COSMIC	98.777	Loss
CMGC_DYRK_HIPK_HIPK2_ST	P51608	MECP2	Q9H2X6	HIPK2	S204	R198T	198	Missense	distal	-6	no	100.574	100.452	EPSD	COSMIC	98.777	Down-regulation
CMGC_DYRK_HIPK_HIPK2_ST	P51608	MECP2	Q9H2X6	HIPK2	S204	Q208K	208	Missense	distal	4	no	100.574	100.150	EPSD	COSMIC	98.777	Down-regulation
CMGC_DYRK_HIPK_HIPK2_ST	P51608	MECP2	Q9H2X6	HIPK2	S216	P217L	217	Missense	proximal	1	no	117.624	-2.661	PhosphoSitePlus;EPSD	COSMIC	98.777	Loss
CMGC_DYRK_HIPK_HIPK2_ST	P51608	MECP2	Q9H2X6	HIPK2	S216	V212G	212	Missense	distal	-4	no	117.624	117.791	PhosphoSitePlus;EPSD	COSMIC	98.777	Up-regulation
CMGC_DYRK_HIPK_HIPK2_ST	P51608	MECP2	Q9H2X6	HIPK2	T228	P230S	230	Missense	proximal	2	no	99.577	99.542	EPSD	COSMIC;CCLE	98.777	Down-regulation
CMGC_DYRK_HIPK_HIPK2_ST	P51608	MECP2	Q9H2X6	HIPK2	T228	S229A	229	Missense	proximal	1	no	99.577	-11.667	EPSD	COSMIC	98.777	Loss
CMGC_DYRK_HIPK_HIPK2_ST	P51608	MECP2	Q9H2X6	HIPK2	T228	P225L	225	Missense	distal	-3	no	99.577	99.796	EPSD	COSMIC	98.777	Up-regulation
CMGC_DYRK_HIPK_HIPK2_ST	P51608	MECP2	Q9H2X6	HIPK2	S229	P230S	230	Missense	proximal	1	no	105.967	88.687	EPSD	COSMIC;CCLE	98.777	Loss
CMGC_DYRK_HIPK_HIPK2_ST	P51608	MECP2	Q9H2X6	HIPK2	S229	S229A	229	Missense	central	0	yes	105.967	0.000	EPSD	COSMIC	98.777	Loss
CMGC_DYRK_HIPK_HIPK2_ST	P51608	MECP2	Q9H2X6	HIPK2	S229	P225L	225	Missense	distal	-4	no	105.967	105.830	EPSD	COSMIC	98.777	Down-regulation
CMGC_DYRK_HIPK_HIPK2_ST	P51608	MECP2	Q9H2X6	HIPK2	S291	E298K	298	Missense	distal	7	no	99.251	99.065	EPSD	COSMIC	98.777	Down-regulation
CMGC_DYRK_HIPK_HIPK2_ST	P51608	MECP2	Q9H2X6	HIPK2	S291	A287V	287	Missense	distal	-4	no	99.251	98.968	EPSD	COSMIC	98.777	Down-regulation
CMGC_DYRK_HIPK_HIPK2_ST	P51608	MECP2	Q9H2X6	HIPK2	S291	E290K	290	Missense	proximal	-1	no	99.251	99.224	EPSD	COSMIC	98.777	Down-regulation
CMGC_DYRK_HIPK_HIPK2_ST	P51608	MECP2	Q9H2X6	HIPK2	S332	G329C	329	Missense	distal	-3	no	99.281	100.226	EPSD	COSMIC	98.777	Up-regulation
CMGC_DYRK_HIPK_HIPK2_ST	P51608	MECP2	Q9H2X6	HIPK2	S332	G329A	329	Missense	distal	-3	no	99.281	99.410	EPSD	COSMIC	98.777	Up-regulation
CMGC_DYRK_HIPK_HIPK2_ST	P51608	MECP2	Q9H2X6	HIPK2	S332	S332N	332	Missense	central	0	yes	99.281	0.000	EPSD	COSMIC	98.777	Loss
CMGC_DYRK_HIPK_HIPK2_ST	P51608	MECP2	Q9H2X6	HIPK2	S350	K352Q	352	Missense	proximal	2	no	107.752	108.150	EPSD	COSMIC	98.777	Up-regulation
CMGC_DYRK_HIPK_HIPK2_ST	P51608	MECP2	Q9H2X6	HIPK2	S350	K352N	352	Missense	proximal	2	no	107.752	107.595	EPSD	COSMIC	98.777	Down-regulation
CMGC_DYRK_HIPK_HIPK2_ST	P51608	MECP2	Q9H2X6	HIPK2	S350	R344Q	344	Missense	distal	-6	no	107.752	108.116	EPSD	COSMIC	98.777	Up-regulation
CMGC_DYRK_HIPK_HIPK2_ST	P51608	MECP2	Q9H2X6	HIPK2	S350	S349R	349	Missense	proximal	-1	no	107.752	106.224	EPSD	COSMIC	98.777	Down-regulation
CMGC_DYRK_HIPK_HIPK2_ST	P51608	MECP2	Q9H2X6	HIPK2	S401	P403H	403	Missense	proximal	2	no	105.338	101.820	EPSD	COSMIC	98.777	Down-regulation
CMGC_DYRK_HIPK_HIPK2_ST	P51608	MECP2	Q9H2X6	HIPK2	S410	P403H	403	Missense	distal	-7	no	101.580	98.356	EPSD	COSMIC	98.777	Loss
CMGC_DYRK_HIPK_HIPK2_ST	P04637	TP53	Q9H2X6	HIPK2	S33	M40I	40	Missense	distal	7	no	103.633	103.765	EPSD	COSMIC	98.777	Up-regulation
CMGC_DYRK_HIPK_HIPK2_ST	P04637	TP53	Q9H2X6	HIPK2	S33	V31I	31	Missense	proximal	-2	no	103.633	103.982	EPSD	COSMIC;GDSC;CCLE	98.777	Up-regulation
CMGC_DYRK_HIPK_HIPK2_ST	P04637	TP53	Q9H2X6	HIPK2	S33	P36L	36	Missense	distal	3	no	103.633	103.409	EPSD	COSMIC;GDSC;CCLE	98.777	Down-regulation
CMGC_DYRK_HIPK_HIPK2_ST	P04637	TP53	Q9H2X6	HIPK2	S33	L35F	35	Missense	proximal	2	no	103.633	102.256	EPSD	COSMIC	98.777	Down-regulation
CMGC_DYRK_HIPK_HIPK2_ST	P04637	TP53	Q9H2X6	HIPK2	S33	Q38L	38	Missense	distal	5	no	103.633	103.771	EPSD	COSMIC	98.777	Up-regulation
CMGC_DYRK_HIPK_HIPK2_ST	P04637	TP53	Q9H2X6	HIPK2	S33	S37T	37	Missense	distal	4	no	103.633	101.876	EPSD	COSMIC	98.777	Down-regulation
CMGC_DYRK_HIPK_HIPK2_ST	P04637	TP53	Q9H2X6	HIPK2	S33	L26P	26	Missense	distal	-7	no	103.633	104.719	EPSD	COSMIC	98.777	Up-regulation
CMGC_DYRK_HIPK_HIPK2_ST	P04637	TP53	Q9H2X6	HIPK2	S33	P36S	36	Missense	distal	3	no	103.633	103.945	EPSD	COSMIC;GDSC;CCLE	98.777	Up-regulation
CMGC_DYRK_HIPK_HIPK2_ST	P04637	TP53	Q9H2X6	HIPK2	S33	A39V	39	Missense	distal	6	no	103.633	103.266	EPSD	COSMIC	98.777	Down-regulation
CMGC_DYRK_HIPK_HIPK2_ST	P04637	TP53	Q9H2X6	HIPK2	S33	A39S	39	Missense	distal	6	no	103.633	103.600	EPSD	COSMIC	98.777	Down-regulation
CMGC_DYRK_HIPK_HIPK2_ST	P04637	TP53	Q9H2X6	HIPK2	S33	N30K	30	Missense	distal	-3	no	103.633	103.263	EPSD	COSMIC	98.777	Down-regulation
CMGC_DYRK_HIPK_HIPK2_ST	P04637	TP53	Q9H2X6	HIPK2	S33	A39T	39	Missense	distal	6	no	103.633	103.506	EPSD	COSMIC	98.777	Down-regulation
CMGC_DYRK_HIPK_HIPK2_ST	P04637	TP53	Q9H2X6	HIPK2	S33	P27T	27	Missense	distal	-6	no	103.633	103.366	EPSD	COSMIC	98.777	Down-regulation
CMGC_DYRK_HIPK_HIPK2_ST	P04637	TP53	Q9H2X6	HIPK2	S33	P36R	36	Missense	distal	3	no	103.633	103.555	EPSD	COSMIC	98.777	Down-regulation
CMGC_DYRK_HIPK_HIPK2_ST	P04637	TP53	Q9H2X6	HIPK2	S33	L35R	35	Missense	proximal	2	no	103.633	102.655	EPSD	COSMIC	98.777	Down-regulation
CMGC_DYRK_HIPK_HIPK2_ST	P04637	TP53	Q9H2X6	HIPK2	S33	L35H	35	Missense	proximal	2	no	103.633	101.664	EPSD	COSMIC	98.777	Down-regulation
CMGC_DYRK_HIPK_HIPK2_ST	P04637	TP53	Q9H2X6	HIPK2	S33	L35P	35	Missense	proximal	2	no	103.633	105.182	EPSD	COSMIC	98.777	Up-regulation
CMGC_DYRK_HIPK_HIPK2_ST	P04637	TP53	Q9H2X6	HIPK2	S33	L35I	35	Missense	proximal	2	no	103.633	103.964	EPSD	COSMIC	98.777	Up-regulation
CMGC_DYRK_HIPK_HIPK2_ST	P04637	TP53	Q9H2X6	HIPK2	S33	L35V	35	Missense	proximal	2	no	103.633	103.714	EPSD	COSMIC	98.777	Up-regulation
CMGC_DYRK_HIPK_HIPK2_ST	P04637	TP53	Q9H2X6	HIPK2	S46	M40I	40	Missense	distal	-6	no	116.500	116.786	PhosphoSitePlus	COSMIC	98.777	Up-regulation
CMGC_DYRK_HIPK_HIPK2_ST	P04637	TP53	Q9H2X6	HIPK2	S46	W53C	53	Missense	distal	7	no	116.500	116.636	PhosphoSitePlus	COSMIC	98.777	Up-regulation
CMGC_DYRK_HIPK_HIPK2_ST	P04637	TP53	Q9H2X6	HIPK2	S46	W53G	53	Missense	distal	7	no	116.500	117.136	PhosphoSitePlus	COSMIC	98.777	Up-regulation
CMGC_DYRK_HIPK_HIPK2_ST	P04637	TP53	Q9H2X6	HIPK2	S46	S46F	46	Missense	central	0	yes	116.500	0.000	PhosphoSitePlus	COSMIC	98.777	Loss
CMGC_DYRK_HIPK_HIPK2_ST	P04637	TP53	Q9H2X6	HIPK2	S46	D49Y	49	Missense	distal	3	no	116.500	116.566	PhosphoSitePlus	COSMIC	98.777	Up-regulation
CMGC_DYRK_HIPK_HIPK2_ST	P04637	TP53	Q9H2X6	HIPK2	S46	P47L	47	Missense	proximal	1	no	116.500	-3.785	PhosphoSitePlus	COSMIC	98.777	Loss
CMGC_DYRK_HIPK_HIPK2_ST	P04637	TP53	Q9H2X6	HIPK2	S46	D49H	49	Missense	distal	3	no	116.500	116.388	PhosphoSitePlus	COSMIC;GDSC;CCLE	98.777	Down-regulation
CMGC_DYRK_HIPK_HIPK2_ST	P04637	TP53	Q9H2X6	HIPK2	S46	P47S	47	Missense	proximal	1	no	116.500	99.220	PhosphoSitePlus	COSMIC	98.777	Down-regulation
CMGC_DYRK_HIPK_HIPK2_ST	P04637	TP53	Q9H2X6	HIPK2	S46	D41N	41	Missense	distal	-5	no	116.500	112.905	PhosphoSitePlus	COSMIC	98.777	Down-regulation
CMGC_DYRK_HIPK_HIPK2_ST	P04637	TP53	Q9H2X6	HIPK2	S46	D48H	48	Missense	proximal	2	no	116.500	114.376	PhosphoSitePlus	COSMIC	98.777	Down-regulation
CMGC_DYRK_HIPK_HIPK2_ST	P04637	TP53	Q9H2X6	HIPK2	S46	D49N	49	Missense	distal	3	no	116.500	116.812	PhosphoSitePlus	COSMIC	98.777	Up-regulation
CMGC_DYRK_HIPK_HIPK2_ST	P04637	TP53	Q9H2X6	HIPK2	S46	M44I	44	Missense	proximal	-2	no	116.500	116.570	PhosphoSitePlus	COSMIC	98.777	Up-regulation
CMGC_DYRK_HIPK_HIPK2_ST	P04637	TP53	Q9H2X6	HIPK2	S46	Q52H	52	Missense	distal	6	no	116.500	115.699	PhosphoSitePlus	COSMIC	98.777	Down-regulation
CMGC_DYRK_HIPK_HIPK2_ST	P04637	TP53	Q9H2X6	HIPK2	S46	D49V	49	Missense	distal	3	no	116.500	116.491	PhosphoSitePlus	COSMIC	98.777	Down-regulation
CMGC_DYRK_HIPK_HIPK2_ST	P04637	TP53	Q9H2X6	HIPK2	S46	A39V	39	Missense	distal	-7	no	116.500	115.491	PhosphoSitePlus	COSMIC	98.777	Down-regulation
CMGC_DYRK_HIPK_HIPK2_ST	P04637	TP53	Q9H2X6	HIPK2	S46	A39S	39	Missense	distal	-7	no	116.500	115.629	PhosphoSitePlus	COSMIC	98.777	Down-regulation
CMGC_DYRK_HIPK_HIPK2_ST	P04637	TP53	Q9H2X6	HIPK2	S46	D42Y	42	Missense	distal	-4	no	116.500	116.291	PhosphoSitePlus	COSMIC	98.777	Down-regulation
CMGC_DYRK_HIPK_HIPK2_ST	P04637	TP53	Q9H2X6	HIPK2	S46	M44R	44	Missense	proximal	-2	no	116.500	116.399	PhosphoSitePlus	COSMIC	98.777	Down-regulation
CMGC_DYRK_HIPK_HIPK2_ST	P04637	TP53	Q9H2X6	HIPK2	S46	S46P	46	Missense	central	0	yes	116.500	0.000	PhosphoSitePlus	COSMIC	98.777	Loss
CMGC_DYRK_HIPK_HIPK2_ST	P04637	TP53	Q9H2X6	HIPK2	S46	M44V	44	Missense	proximal	-2	no	116.500	116.220	PhosphoSitePlus	COSMIC	98.777	Down-regulation
CMGC_DYRK_HIPK_HIPK2_ST	P04637	TP53	Q9H2X6	HIPK2	S46	L45P	45	Missense	proximal	-1	no	116.500	117.890	PhosphoSitePlus	COSMIC	98.777	Up-regulation
CMGC_DYRK_HIPK_HIPK2_ST	P04637	TP53	Q9H2X6	HIPK2	S46	M44T	44	Missense	proximal	-2	no	116.500	116.359	PhosphoSitePlus	COSMIC	98.777	Down-regulation
CMGC_DYRK_HIPK_HIPK2_ST	P04637	TP53	Q9H2X6	HIPK2	S46	A39T	39	Missense	distal	-7	no	116.500	114.973	PhosphoSitePlus	COSMIC	98.777	Down-regulation
CMGC_DYRK_HIPK_HIPK2_ST	P04637	TP53	Q9H2X6	HIPK2	S46	L43F	43	Missense	distal	-3	no	116.500	116.818	PhosphoSitePlus	COSMIC	98.777	Up-regulation
CMGC_DYRK_HIPK_HIPK2_ST	P04637	TP53	Q9H2X6	HIPK2	S46	D41H	41	Missense	distal	-5	no	116.500	107.058	PhosphoSitePlus	COSMIC	98.777	Down-regulation
CMGC_DYRK_HIPK_HIPK2_ST	P04637	TP53	Q9H2X6	HIPK2	S46	D49E	49	Missense	distal	3	no	116.500	117.268	PhosphoSitePlus	COSMIC	98.777	Up-regulation
CMGC_DYRK_HIPK_HIPK2_ST	P04637	TP53	Q9H2X6	HIPK2	S46	D49G	49	Missense	distal	3	no	116.500	116.755	PhosphoSitePlus	COSMIC	98.777	Up-regulation
CMGC_DYRK_HIPK_HIPK2_ST	P04637	TP53	Q9H2X6	HIPK2	S46	D48A	48	Missense	proximal	2	no	116.500	118.019	PhosphoSitePlus	COSMIC	98.777	Up-regulation
CMGC_DYRK_HIPK_HIPK2_ST	P04637	TP53	Q9H2X6	HIPK2	S46	D48Y	48	Missense	proximal	2	no	116.500	115.709	PhosphoSitePlus	COSMIC	98.777	Down-regulation
CMGC_DYRK_HIPK_HIPK2_ST	P04637	TP53	Q9H2X6	HIPK2	S46	D48E	48	Missense	proximal	2	no	116.500	118.269	PhosphoSitePlus	COSMIC	98.777	Up-regulation
CMGC_DYRK_HIPK_HIPK2_ST	P04637	TP53	Q9H2X6	HIPK2	S46	D49I	49	Missense	distal	3	no	116.500	116.942	PhosphoSitePlus	COSMIC	98.777	Up-regulation
CMGC_DYRK_HIPK_HIPK2_ST	P04637	TP53	Q9H2X6	HIPK2	S46	D41E	41	Missense	distal	-5	no	116.500	118.576	PhosphoSitePlus	COSMIC	98.777	Up-regulation
CMGC_DYRK_HIPK_HIPK2_ST	P04637	TP53	Q9H2X6	HIPK2	T81	A76T	76	Missense	distal	-5	no	98.599	99.171	EPSD	COSMIC	98.777	Gain
CMGC_DYRK_HIPK_HIPK2_ST	P04637	TP53	Q9H2X6	HIPK2	T81	P85S	85	Missense	distal	4	no	98.599	99.732	EPSD	COSMIC	98.777	Gain
CMGC_DYRK_HIPK_HIPK2_ST	P04637	TP53	Q9H2X6	HIPK2	T81	A84G	84	Missense	distal	3	no	98.599	98.837	EPSD	COSMIC	98.777	Gain
CMGC_DYRK_HIPK_HIPK2_ST	P04637	TP53	Q9H2X6	HIPK2	T81	A78V	78	Missense	distal	-3	no	98.599	98.823	EPSD	COSMIC	98.777	Gain
CMGC_DYRK_HIPK_HIPK2_ST	P04637	TP53	Q9H2X6	HIPK2	T81	P80S	80	Missense	proximal	-1	no	98.599	98.916	EPSD	COSMIC	98.777	Gain
CMGC_DYRK_HIPK_HIPK2_ST	P04637	TP53	Q9H2X6	HIPK2	T81	A83E	83	Missense	proximal	2	no	98.599	98.849	EPSD	COSMIC	98.777	Gain
CMGC_DYRK_HIPK_HIPK2_ST	P04637	TP53	Q9H2X6	HIPK2	T81	A76V	76	Missense	distal	-5	no	98.599	101.145	EPSD	COSMIC	98.777	Gain
CMGC_DYRK_HIPK_HIPK2_ST	P04637	TP53	Q9H2X6	HIPK2	S127	N131K	131	Missense	distal	4	no	96.897	100.026	EPSD	COSMIC;CCLE	98.777	Gain
CMGC_DYRK_HIPK_HIPK2_ST	P04637	TP53	Q9H2X6	HIPK2	T150	P151N	151	Missense	proximal	1	no	104.776	54.544	EPSD	COSMIC	98.777	Loss
CMGC_DYRK_HIPK_HIPK2_ST	P04637	TP53	Q9H2X6	HIPK2	T150	P152A	152	Missense	proximal	2	no	104.776	104.901	EPSD	COSMIC	98.777	Up-regulation
CMGC_DYRK_HIPK_HIPK2_ST	P04637	TP53	Q9H2X6	HIPK2	T150	P152T	152	Missense	proximal	2	no	104.776	104.198	EPSD	COSMIC	98.777	Down-regulation
CMGC_DYRK_HIPK_HIPK2_ST	P04637	TP53	Q9H2X6	HIPK2	T150	P152H	152	Missense	proximal	2	no	104.776	101.258	EPSD	COSMIC	98.777	Down-regulation
CMGC_DYRK_HIPK_HIPK2_ST	P04637	TP53	Q9H2X6	HIPK2	T150	P153T	153	Missense	distal	3	no	104.776	104.313	EPSD	COSMIC	98.777	Down-regulation
CMGC_DYRK_HIPK_HIPK2_ST	P04637	TP53	Q9H2X6	HIPK2	T150	V147I	147	Missense	distal	-3	no	104.776	104.506	EPSD	COSMIC	98.777	Down-regulation
CMGC_DYRK_HIPK_HIPK2_ST	P04637	TP53	Q9H2X6	HIPK2	T150	P153L	153	Missense	distal	3	no	104.776	104.552	EPSD	COSMIC	98.777	Down-regulation
CMGC_DYRK_HIPK_HIPK2_ST	P04637	TP53	Q9H2X6	HIPK2	T150	V147D	147	Missense	distal	-3	no	104.776	104.565	EPSD	COSMIC;GDSC;CCLE	98.777	Down-regulation
CMGC_DYRK_HIPK_HIPK2_ST	P04637	TP53	Q9H2X6	HIPK2	T150	S149P	149	Missense	proximal	-1	no	104.776	104.459	EPSD	COSMIC	98.777	Down-regulation
CMGC_DYRK_HIPK_HIPK2_ST	P04637	TP53	Q9H2X6	HIPK2	T150	P152K	152	Missense	proximal	2	no	104.776	104.111	EPSD	COSMIC	98.777	Down-regulation
CMGC_DYRK_HIPK_HIPK2_ST	P04637	TP53	Q9H2X6	HIPK2	T150	P153S	153	Missense	distal	3	no	104.776	105.088	EPSD	COSMIC	98.777	Up-regulation
CMGC_DYRK_HIPK_HIPK2_ST	P04637	TP53	Q9H2X6	HIPK2	T150	G154C	154	Missense	distal	4	no	104.776	95.484	EPSD	COSMIC	98.777	Loss
CMGC_DYRK_HIPK_HIPK2_ST	P04637	TP53	Q9H2X6	HIPK2	T150	S149F	149	Missense	proximal	-1	no	104.776	102.514	EPSD	COSMIC	98.777	Down-regulation
CMGC_DYRK_HIPK_HIPK2_ST	P04637	TP53	Q9H2X6	HIPK2	T150	G154D	154	Missense	distal	4	no	104.776	101.853	EPSD	COSMIC	98.777	Down-regulation
CMGC_DYRK_HIPK_HIPK2_ST	P04637	TP53	Q9H2X6	HIPK2	T150	V157I	157	Missense	distal	7	no	104.776	104.922	EPSD	COSMIC	98.777	Up-regulation
CMGC_DYRK_HIPK_HIPK2_ST	P04637	TP53	Q9H2X6	HIPK2	T150	W146R	146	Missense	distal	-4	no	104.776	105.207	EPSD	COSMIC	98.777	Up-regulation
CMGC_DYRK_HIPK_HIPK2_ST	P04637	TP53	Q9H2X6	HIPK2	T150	Q144R	144	Missense	distal	-6	no	104.776	104.412	EPSD	COSMIC	98.777	Down-regulation
CMGC_DYRK_HIPK_HIPK2_ST	P04637	TP53	Q9H2X6	HIPK2	T150	D148V	148	Missense	proximal	-2	no	104.776	104.606	EPSD	COSMIC	98.777	Down-regulation
CMGC_DYRK_HIPK_HIPK2_ST	P04637	TP53	Q9H2X6	HIPK2	T150	S149Y	149	Missense	proximal	-1	no	104.776	103.009	EPSD	COSMIC	98.777	Down-regulation
CMGC_DYRK_HIPK_HIPK2_ST	P04637	TP53	Q9H2X6	HIPK2	T150	T150I	150	Missense	central	0	yes	104.776	0.000	EPSD	COSMIC	98.777	Loss
CMGC_DYRK_HIPK_HIPK2_ST	P04637	TP53	Q9H2X6	HIPK2	T150	S149T	149	Missense	proximal	-1	no	104.776	102.979	EPSD	COSMIC	98.777	Down-regulation
CMGC_DYRK_HIPK_HIPK2_ST	P04637	TP53	Q9H2X6	HIPK2	T150	W146G	146	Missense	distal	-4	no	104.776	105.251	EPSD	COSMIC	98.777	Up-regulation
CMGC_DYRK_HIPK_HIPK2_ST	P04637	TP53	Q9H2X6	HIPK2	T150	L145M	145	Missense	distal	-5	no	104.776	103.756	EPSD	COSMIC	98.777	Down-regulation
CMGC_DYRK_HIPK_HIPK2_ST	P04637	TP53	Q9H2X6	HIPK2	T150	V143L	143	Missense	distal	-7	no	104.776	104.478	EPSD	COSMIC	98.777	Down-regulation
CMGC_DYRK_HIPK_HIPK2_ST	P04637	TP53	Q9H2X6	HIPK2	T150	R156S	156	Missense	distal	6	no	104.776	105.217	EPSD	COSMIC	98.777	Up-regulation
CMGC_DYRK_HIPK_HIPK2_ST	P04637	TP53	Q9H2X6	HIPK2	T150	D148E	148	Missense	proximal	-2	no	104.776	105.042	EPSD	COSMIC	98.777	Up-regulation
CMGC_DYRK_HIPK_HIPK2_ST	P04637	TP53	Q9H2X6	HIPK2	T150	V147F	147	Missense	distal	-3	no	104.776	105.053	EPSD	COSMIC	98.777	Up-regulation
CMGC_DYRK_HIPK_HIPK2_ST	P04637	TP53	Q9H2X6	HIPK2	T150	T155A	155	Missense	distal	5	no	104.776	104.747	EPSD	COSMIC	98.777	Down-regulation
CMGC_DYRK_HIPK_HIPK2_ST	P04637	TP53	Q9H2X6	HIPK2	T150	V147E	147	Missense	distal	-3	no	104.776	104.260	EPSD	COSMIC	98.777	Down-regulation
CMGC_DYRK_HIPK_HIPK2_ST	P04637	TP53	Q9H2X6	HIPK2	T150	G154I	154	Missense	distal	4	no	104.776	103.913	EPSD	COSMIC	98.777	Down-regulation
CMGC_DYRK_HIPK_HIPK2_ST	P04637	TP53	Q9H2X6	HIPK2	T150	D148G	148	Missense	proximal	-2	no	104.776	105.134	EPSD	COSMIC	98.777	Up-regulation
CMGC_DYRK_HIPK_HIPK2_ST	P04637	TP53	Q9H2X6	HIPK2	T150	Q144K	144	Missense	distal	-6	no	104.776	104.647	EPSD	COSMIC	98.777	Down-regulation
CMGC_DYRK_HIPK_HIPK2_ST	P04637	TP53	Q9H2X6	HIPK2	T150	V147A	147	Missense	distal	-3	no	104.776	104.552	EPSD	COSMIC	98.777	Down-regulation
CMGC_DYRK_HIPK_HIPK2_ST	P04637	TP53	Q9H2X6	HIPK2	T150	L145V	145	Missense	distal	-5	no	104.776	105.902	EPSD	COSMIC	98.777	Up-regulation
CMGC_DYRK_HIPK_HIPK2_ST	P04637	TP53	Q9H2X6	HIPK2	T150	T150K	150	Missense	central	0	yes	104.776	0.000	EPSD	COSMIC	98.777	Loss
CMGC_DYRK_HIPK_HIPK2_ST	P04637	TP53	Q9H2X6	HIPK2	T150	P153H	153	Missense	distal	3	no	104.776	104.210	EPSD	COSMIC	98.777	Down-regulation
CMGC_DYRK_HIPK_HIPK2_ST	P04637	TP53	Q9H2X6	HIPK2	T150	V157E	157	Missense	distal	7	no	104.776	105.296	EPSD	COSMIC	98.777	Up-regulation
CMGC_DYRK_HIPK_HIPK2_ST	P04637	TP53	Q9H2X6	HIPK2	T150	T155S	155	Missense	distal	5	no	104.776	104.647	EPSD	COSMIC;CCLE	98.777	Down-regulation
CMGC_DYRK_HIPK_HIPK2_ST	P04637	TP53	Q9H2X6	HIPK2	T150	D148H	148	Missense	proximal	-2	no	104.776	104.378	EPSD	COSMIC	98.777	Down-regulation
CMGC_DYRK_HIPK_HIPK2_ST	P04637	TP53	Q9H2X6	HIPK2	T150	P153A	153	Missense	distal	3	no	104.776	104.339	EPSD	COSMIC	98.777	Down-regulation
CMGC_DYRK_HIPK_HIPK2_ST	P04637	TP53	Q9H2X6	HIPK2	T150	T150R	150	Missense	central	0	yes	104.776	0.000	EPSD	COSMIC	98.777	Loss
CMGC_DYRK_HIPK_HIPK2_ST	P04637	TP53	Q9H2X6	HIPK2	T150	T155L	155	Missense	distal	5	no	104.776	104.759	EPSD	COSMIC	98.777	Down-regulation
CMGC_DYRK_HIPK_HIPK2_ST	P04637	TP53	Q9H2X6	HIPK2	T150	G154A	154	Missense	distal	4	no	104.776	103.702	EPSD	COSMIC	98.777	Down-regulation
CMGC_DYRK_HIPK_HIPK2_ST	P04637	TP53	Q9H2X6	HIPK2	T150	T150A	150	Missense	central	0	yes	104.776	0.000	EPSD	COSMIC	98.777	Loss
CMGC_DYRK_HIPK_HIPK2_ST	P04637	TP53	Q9H2X6	HIPK2	T150	W146C	146	Missense	distal	-4	no	104.776	104.828	EPSD	COSMIC	98.777	Up-regulation
CMGC_DYRK_HIPK_HIPK2_ST	P04637	TP53	Q9H2X6	HIPK2	T150	P153F	153	Missense	distal	3	no	104.776	104.340	EPSD	COSMIC	98.777	Down-regulation
CMGC_DYRK_HIPK_HIPK2_ST	P04637	TP53	Q9H2X6	HIPK2	T150	D148Y	148	Missense	proximal	-2	no	104.776	104.615	EPSD	COSMIC	98.777	Down-regulation
CMGC_DYRK_HIPK_HIPK2_ST	P04637	TP53	Q9H2X6	HIPK2	T150	G154R	154	Missense	distal	4	no	104.776	103.097	EPSD	COSMIC	98.777	Down-regulation
CMGC_DYRK_HIPK_HIPK2_ST	P04637	TP53	Q9H2X6	HIPK2	S313	T312S	312	Missense	proximal	-1	no	98.044	99.841	EPSD	COSMIC	98.777	Gain
CMGC_DYRK_HIPK_HIPK2_ST	P04637	TP53	Q9H2X6	HIPK2	S313	R306P	306	Missense	distal	-7	no	98.044	98.927	EPSD	COSMIC	98.777	Gain
CMGC_DYRK_HIPK_HIPK2_ST	P04637	TP53	Q9H2X6	HIPK2	S313	R306Q	306	Missense	distal	-7	no	98.044	99.171	EPSD	COSMIC	98.777	Gain
CMGC_DYRK_HIPK_HIPK2_ST	P04637	TP53	Q9H2X6	HIPK2	S313	L308V	308	Missense	distal	-5	no	98.044	99.170	EPSD	COSMIC	98.777	Gain
CMGC_DYRK_HIPK_HIPK2_ST	P04637	TP53	Q9H2X6	HIPK2	S314	N310T	310	Missense	distal	-4	no	99.315	99.353	EPSD	COSMIC	98.777	Up-regulation
CMGC_DYRK_HIPK_HIPK2_ST	P04637	TP53	Q9H2X6	HIPK2	S314	Q317R	317	Missense	distal	3	no	99.315	98.672	EPSD	COSMIC	98.777	Loss
CMGC_DYRK_HIPK_HIPK2_ST	P04637	TP53	Q9H2X6	HIPK2	S314	P309S	309	Missense	distal	-5	no	99.315	95.053	EPSD	COSMIC;GDSC;CCLE	98.777	Loss
CMGC_DYRK_HIPK_HIPK2_ST	P04637	TP53	Q9H2X6	HIPK2	S314	K319E	319	Missense	distal	5	no	99.315	99.252	EPSD	COSMIC	98.777	Down-regulation
CMGC_DYRK_HIPK_HIPK2_ST	P04637	TP53	Q9H2X6	HIPK2	S314	K320N	320	Missense	distal	6	no	99.315	99.216	EPSD	COSMIC;GDSC;CCLE	98.777	Down-regulation
CMGC_DYRK_HIPK_HIPK2_ST	P04637	TP53	Q9H2X6	HIPK2	S314	N310L	310	Missense	distal	-4	no	99.315	99.347	EPSD	COSMIC	98.777	Up-regulation
CMGC_DYRK_HIPK_HIPK2_ST	P04637	TP53	Q9H2X6	HIPK2	S314	T312S	312	Missense	proximal	-2	no	99.315	99.677	EPSD	COSMIC	98.777	Up-regulation
CMGC_DYRK_HIPK_HIPK2_ST	P04637	TP53	Q9H2X6	HIPK2	S314	N311Y	311	Missense	distal	-3	no	99.315	99.666	EPSD	COSMIC	98.777	Up-regulation
CMGC_DYRK_HIPK_HIPK2_ST	P04637	TP53	Q9H2X6	HIPK2	S314	A307T	307	Missense	distal	-7	no	99.315	97.788	EPSD	COSMIC	98.777	Loss
CMGC_DYRK_HIPK_HIPK2_ST	P04637	TP53	Q9H2X6	HIPK2	S314	N311K	311	Missense	distal	-3	no	99.315	98.946	EPSD	COSMIC	98.777	Down-regulation
CMGC_DYRK_HIPK_HIPK2_ST	P04637	TP53	Q9H2X6	HIPK2	S314	Q317K	317	Missense	distal	3	no	99.315	98.696	EPSD	COSMIC	98.777	Loss
CMGC_DYRK_HIPK_HIPK2_ST	P04637	TP53	Q9H2X6	HIPK2	S314	S315P	315	Missense	proximal	1	no	99.315	116.595	EPSD	COSMIC	98.777	Up-regulation
CMGC_DYRK_HIPK_HIPK2_ST	P04637	TP53	Q9H2X6	HIPK2	S314	N310H	310	Missense	distal	-4	no	99.315	99.010	EPSD	COSMIC	98.777	Down-regulation
CMGC_DYRK_HIPK_HIPK2_ST	P04637	TP53	Q9H2X6	HIPK2	S314	S314C	314	Missense	central	0	yes	99.315	0.000	EPSD	COSMIC	98.777	Loss
CMGC_DYRK_HIPK_HIPK2_ST	P04637	TP53	Q9H2X6	HIPK2	S314	P318A	318	Missense	distal	4	no	99.315	99.447	EPSD	COSMIC	98.777	Up-regulation
CMGC_DYRK_HIPK_HIPK2_ST	P04637	TP53	Q9H2X6	HIPK2	S314	P316L	316	Missense	proximal	2	no	99.315	97.766	EPSD	COSMIC	98.777	Loss
CMGC_DYRK_HIPK_HIPK2_ST	P04637	TP53	Q9H2X6	HIPK2	S314	L308M	308	Missense	distal	-6	no	99.315	99.165	EPSD	COSMIC	98.777	Down-regulation
CMGC_DYRK_HIPK_HIPK2_ST	P04637	TP53	Q9H2X6	HIPK2	S314	S313C	313	Missense	proximal	-1	no	99.315	95.918	EPSD	COSMIC	98.777	Loss
CMGC_DYRK_HIPK_HIPK2_ST	P04637	TP53	Q9H2X6	HIPK2	S314	N311H	311	Missense	distal	-3	no	99.315	99.945	EPSD	COSMIC	98.777	Up-regulation
CMGC_DYRK_HIPK_HIPK2_ST	P04637	TP53	Q9H2X6	HIPK2	S314	L308V	308	Missense	distal	-6	no	99.315	99.079	EPSD	COSMIC	98.777	Down-regulation
CMGC_DYRK_HIPK_HIPK2_ST	P04637	TP53	Q9H2X6	HIPK2	S314	S314F	314	Missense	central	0	yes	99.315	0.000	EPSD	COSMIC	98.777	Loss
CMGC_DYRK_HIPK_HIPK2_ST	P04637	TP53	Q9H2X6	HIPK2	S314	K319R	319	Missense	distal	5	no	99.315	99.412	EPSD	COSMIC	98.777	Up-regulation
CMGC_DYRK_HIPK_HIPK2_ST	P04637	TP53	Q9H2X6	HIPK2	S314	T312A	312	Missense	proximal	-2	no	99.315	99.534	EPSD	COSMIC	98.777	Up-regulation
CMGC_DYRK_HIPK_HIPK2_ST	P04637	TP53	Q9H2X6	HIPK2	S314	N310D	310	Missense	distal	-4	no	99.315	99.367	EPSD	COSMIC	98.777	Up-regulation
CMGC_DYRK_HIPK_HIPK2_ST	P04637	TP53	Q9H2X6	HIPK2	S314	N311D	311	Missense	distal	-3	no	99.315	99.251	EPSD	COSMIC	98.777	Down-regulation
CMGC_DYRK_HIPK_HIPK2_ST	P04637	TP53	Q9H2X6	HIPK2	S314	P309R	309	Missense	distal	-5	no	99.315	97.533	EPSD	COSMIC	98.777	Loss
CMGC_DYRK_HIPK_HIPK2_ST	P04637	TP53	Q9H2X6	HIPK2	S314	S313N	313	Missense	proximal	-1	no	99.315	98.267	EPSD	COSMIC	98.777	Loss
CMGC_DYRK_HIPK_HIPK2_ST	P04637	TP53	Q9H2X6	HIPK2	S314	Q317P	317	Missense	distal	3	no	99.315	98.750	EPSD	COSMIC	98.777	Loss
CMGC_DYRK_HIPK_HIPK2_ST	P04637	TP53	Q9H2X6	HIPK2	S314	A307S	307	Missense	distal	-7	no	99.315	98.444	EPSD	COSMIC	98.777	Loss
CMGC_DYRK_HIPK_HIPK2_ST	P04637	TP53	Q9H2X6	HIPK2	S314	P316S	316	Missense	proximal	2	no	99.315	99.280	EPSD	COSMIC	98.777	Down-regulation
CMGC_DYRK_HIPK_HIPK2_ST	P04637	TP53	Q9H2X6	HIPK2	S315	N310T	310	Missense	distal	-5	no	106.507	105.005	EPSD	COSMIC	98.777	Down-regulation
CMGC_DYRK_HIPK_HIPK2_ST	P04637	TP53	Q9H2X6	HIPK2	S315	Q317R	317	Missense	proximal	2	no	106.507	104.246	EPSD	COSMIC	98.777	Down-regulation
CMGC_DYRK_HIPK_HIPK2_ST	P04637	TP53	Q9H2X6	HIPK2	S315	P309S	309	Missense	distal	-6	no	106.507	106.513	EPSD	COSMIC;GDSC;CCLE	98.777	Up-regulation
CMGC_DYRK_HIPK_HIPK2_ST	P04637	TP53	Q9H2X6	HIPK2	S315	K319E	319	Missense	distal	4	no	106.507	106.029	EPSD	COSMIC	98.777	Down-regulation
CMGC_DYRK_HIPK_HIPK2_ST	P04637	TP53	Q9H2X6	HIPK2	S315	P322L	322	Missense	distal	7	no	106.507	106.329	EPSD	COSMIC	98.777	Down-regulation
CMGC_DYRK_HIPK_HIPK2_ST	P04637	TP53	Q9H2X6	HIPK2	S315	K320N	320	Missense	distal	5	no	106.507	106.558	EPSD	COSMIC;GDSC;CCLE	98.777	Up-regulation
CMGC_DYRK_HIPK_HIPK2_ST	P04637	TP53	Q9H2X6	HIPK2	S315	N310L	310	Missense	distal	-5	no	106.507	105.853	EPSD	COSMIC	98.777	Down-regulation
CMGC_DYRK_HIPK_HIPK2_ST	P04637	TP53	Q9H2X6	HIPK2	S315	T312S	312	Missense	distal	-3	no	106.507	106.049	EPSD	COSMIC	98.777	Down-regulation
CMGC_DYRK_HIPK_HIPK2_ST	P04637	TP53	Q9H2X6	HIPK2	S315	N311Y	311	Missense	distal	-4	no	106.507	106.350	EPSD	COSMIC	98.777	Down-regulation
CMGC_DYRK_HIPK_HIPK2_ST	P04637	TP53	Q9H2X6	HIPK2	S315	P322R	322	Missense	distal	7	no	106.507	105.941	EPSD	COSMIC	98.777	Down-regulation
CMGC_DYRK_HIPK_HIPK2_ST	P04637	TP53	Q9H2X6	HIPK2	S315	N311K	311	Missense	distal	-4	no	106.507	106.649	EPSD	COSMIC	98.777	Up-regulation
CMGC_DYRK_HIPK_HIPK2_ST	P04637	TP53	Q9H2X6	HIPK2	S315	Q317K	317	Missense	proximal	2	no	106.507	106.108	EPSD	COSMIC	98.777	Down-regulation
CMGC_DYRK_HIPK_HIPK2_ST	P04637	TP53	Q9H2X6	HIPK2	S315	S315P	315	Missense	central	0	yes	106.507	0.000	EPSD	COSMIC	98.777	Loss
CMGC_DYRK_HIPK_HIPK2_ST	P04637	TP53	Q9H2X6	HIPK2	S315	N310H	310	Missense	distal	-5	no	106.507	100.659	EPSD	COSMIC	98.777	Down-regulation
CMGC_DYRK_HIPK_HIPK2_ST	P04637	TP53	Q9H2X6	HIPK2	S315	S314C	314	Missense	proximal	-1	no	106.507	103.110	EPSD	COSMIC	98.777	Down-regulation
CMGC_DYRK_HIPK_HIPK2_ST	P04637	TP53	Q9H2X6	HIPK2	S315	P318A	318	Missense	distal	3	no	106.507	106.070	EPSD	COSMIC	98.777	Down-regulation
CMGC_DYRK_HIPK_HIPK2_ST	P04637	TP53	Q9H2X6	HIPK2	S315	P316L	316	Missense	proximal	1	no	106.507	-13.778	EPSD	COSMIC	98.777	Loss
CMGC_DYRK_HIPK_HIPK2_ST	P04637	TP53	Q9H2X6	HIPK2	S315	L308M	308	Missense	distal	-7	no	106.507	106.099	EPSD	COSMIC	98.777	Down-regulation
CMGC_DYRK_HIPK_HIPK2_ST	P04637	TP53	Q9H2X6	HIPK2	S315	S313C	313	Missense	proximal	-2	no	106.507	105.486	EPSD	COSMIC	98.777	Down-regulation
CMGC_DYRK_HIPK_HIPK2_ST	P04637	TP53	Q9H2X6	HIPK2	S315	N311H	311	Missense	distal	-4	no	106.507	106.202	EPSD	COSMIC	98.777	Down-regulation
CMGC_DYRK_HIPK_HIPK2_ST	P04637	TP53	Q9H2X6	HIPK2	S315	L308V	308	Missense	distal	-7	no	106.507	106.805	EPSD	COSMIC	98.777	Up-regulation
CMGC_DYRK_HIPK_HIPK2_ST	P04637	TP53	Q9H2X6	HIPK2	S315	S314F	314	Missense	proximal	-1	no	106.507	104.244	EPSD	COSMIC	98.777	Down-regulation
CMGC_DYRK_HIPK_HIPK2_ST	P04637	TP53	Q9H2X6	HIPK2	S315	K319R	319	Missense	distal	4	no	106.507	104.458	EPSD	COSMIC	98.777	Down-regulation
CMGC_DYRK_HIPK_HIPK2_ST	P04637	TP53	Q9H2X6	HIPK2	S315	T312A	312	Missense	distal	-3	no	106.507	106.266	EPSD	COSMIC	98.777	Down-regulation
CMGC_DYRK_HIPK_HIPK2_ST	P04637	TP53	Q9H2X6	HIPK2	S315	N310D	310	Missense	distal	-5	no	106.507	110.102	EPSD	COSMIC	98.777	Up-regulation
CMGC_DYRK_HIPK_HIPK2_ST	P04637	TP53	Q9H2X6	HIPK2	S315	N311D	311	Missense	distal	-4	no	106.507	106.559	EPSD	COSMIC	98.777	Up-regulation
CMGC_DYRK_HIPK_HIPK2_ST	P04637	TP53	Q9H2X6	HIPK2	S315	P309R	309	Missense	distal	-6	no	106.507	106.363	EPSD	COSMIC	98.777	Down-regulation
CMGC_DYRK_HIPK_HIPK2_ST	P04637	TP53	Q9H2X6	HIPK2	S315	S313N	313	Missense	proximal	-2	no	106.507	106.250	EPSD	COSMIC	98.777	Down-regulation
CMGC_DYRK_HIPK_HIPK2_ST	P04637	TP53	Q9H2X6	HIPK2	S315	Q317P	317	Missense	proximal	2	no	106.507	106.774	EPSD	COSMIC	98.777	Up-regulation
CMGC_DYRK_HIPK_HIPK2_ST	P04637	TP53	Q9H2X6	HIPK2	S315	P316S	316	Missense	proximal	1	no	106.507	89.227	EPSD	COSMIC	98.777	Loss
CMGC_DYRK_HIPK_HIPK2_ST	P04637	TP53	Q9H2X6	HIPK2	S362	S367F	367	Missense	distal	5	no	100.771	100.902	EPSD	COSMIC	98.777	Up-regulation
CMGC_DYRK_HIPK_HIPK2_ST	P04637	TP53	Q9H2X6	HIPK2	S362	G361E	361	Missense	proximal	-1	no	100.771	101.206	EPSD	COSMIC	98.777	Up-regulation
CMGC_DYRK_HIPK_HIPK2_ST	P04637	TP53	Q9H2X6	HIPK2	S362	E358V	358	Missense	distal	-4	no	100.771	100.491	EPSD	COSMIC	98.777	Down-regulation
CMGC_DYRK_HIPK_HIPK2_ST	P04637	TP53	Q9H2X6	HIPK2	S362	P359S	359	Missense	distal	-3	no	100.771	100.590	EPSD	COSMIC	98.777	Down-regulation
CMGC_DYRK_HIPK_HIPK2_ST	P04637	TP53	Q9H2X6	HIPK2	S362	A364D	364	Missense	proximal	2	no	100.771	99.252	EPSD	COSMIC	98.777	Down-regulation
CMGC_DYRK_HIPK_HIPK2_ST	P04637	TP53	Q9H2X6	HIPK2	S362	H365Y	365	Missense	distal	3	no	100.771	100.949	EPSD	COSMIC	98.777	Up-regulation
CMGC_DYRK_HIPK_HIPK2_ST	P04637	TP53	Q9H2X6	HIPK2	S362	G360A	360	Missense	proximal	-2	no	100.771	100.601	EPSD	COSMIC	98.777	Down-regulation
CMGC_DYRK_HIPK_HIPK2_ST	P04637	TP53	Q9H2X6	HIPK2	S362	A364T	364	Missense	proximal	2	no	100.771	100.069	EPSD	COSMIC	98.777	Down-regulation
CMGC_DYRK_HIPK_HIPK2_ST	P04637	TP53	Q9H2X6	HIPK2	S362	G356W	356	Missense	distal	-6	no	100.771	100.289	EPSD	COSMIC	98.777	Down-regulation
CMGC_DYRK_HIPK_HIPK2_ST	P04637	TP53	Q9H2X6	HIPK2	S362	S366A	366	Missense	distal	4	no	100.771	99.771	EPSD	COSMIC	98.777	Down-regulation
CMGC_DYRK_HIPK_HIPK2_ST	P04637	TP53	Q9H2X6	HIPK2	S362	E358Q	358	Missense	distal	-4	no	100.771	100.783	EPSD	COSMIC	98.777	Up-regulation
CMGC_DYRK_HIPK_HIPK2_ST	P04637	TP53	Q9H2X6	HIPK2	S362	G361R	361	Missense	proximal	-1	no	100.771	99.873	EPSD	COSMIC	98.777	Down-regulation
CMGC_DYRK_HIPK_HIPK2_ST	P04637	TP53	Q9H2X6	HIPK2	S362	E358K	358	Missense	distal	-4	no	100.771	100.847	EPSD	COSMIC	98.777	Up-regulation
CMGC_DYRK_HIPK_HIPK2_ST	O15297	PPM1D	Q9H2X6	HIPK2	S40	S46P	46	Missense	distal	6	no	110.847	110.936	EPSD	COSMIC	98.777	Up-regulation
CMGC_DYRK_HIPK_HIPK2_ST	O15297	PPM1D	Q9H2X6	HIPK2	S40	S44W	44	Missense	distal	4	no	110.847	100.379	EPSD	COSMIC	98.777	Down-regulation
CMGC_DYRK_HIPK_HIPK2_ST	O15297	PPM1D	Q9H2X6	HIPK2	S54	S54L	54	Missense	central	0	yes	107.743	0.000	EPSD	COSMIC	98.777	Loss
CMGC_DYRK_HIPK_HIPK2_ST	O15297	PPM1D	Q9H2X6	HIPK2	S54	A57V	57	Missense	distal	3	no	107.743	107.717	EPSD	COSMIC	98.777	Down-regulation
CMGC_DYRK_HIPK_HIPK2_ST	O15297	PPM1D	Q9H2X6	HIPK2	S54	P53Q	53	Missense	proximal	-1	no	107.743	107.571	EPSD	COSMIC	98.777	Down-regulation
CMGC_DYRK_HIPK_HIPK2_ST	O15297	PPM1D	Q9H2X6	HIPK2	S54	P59S	59	Missense	distal	5	no	107.743	107.744	EPSD	COSMIC	98.777	Up-regulation
CMGC_DYRK_HIPK_HIPK2_ST	O15297	PPM1D	Q9H2X6	HIPK2	S54	P51S	51	Missense	distal	-3	no	107.743	107.562	EPSD	COSMIC	98.777	Down-regulation
CMGC_DYRK_HIPK_HIPK2_ST	O15297	PPM1D	Q9H2X6	HIPK2	S54	A57T	57	Missense	distal	3	no	107.743	107.717	EPSD	COSMIC	98.777	Down-regulation
CMGC_DYRK_HIPK_HIPK2_ST	O15297	PPM1D	Q9H2X6	HIPK2	S64	A57V	57	Missense	distal	-7	no	104.842	103.833	EPSD	COSMIC	98.777	Down-regulation
CMGC_DYRK_HIPK_HIPK2_ST	O15297	PPM1D	Q9H2X6	HIPK2	S64	P59S	59	Missense	distal	-5	no	104.842	100.580	EPSD	COSMIC	98.777	Down-regulation
CMGC_DYRK_HIPK_HIPK2_ST	O15297	PPM1D	Q9H2X6	HIPK2	S64	A57T	57	Missense	distal	-7	no	104.842	103.315	EPSD	COSMIC	98.777	Down-regulation
CMGC_DYRK_HIPK_HIPK2_ST	O15297	PPM1D	Q9H2X6	HIPK2	S64	P68T	68	Missense	distal	4	no	104.842	104.218	EPSD	COSMIC	98.777	Down-regulation
CMGC_DYRK_HIPK_HIPK2_ST	O15297	PPM1D	Q9H2X6	HIPK2	S85	L79V	79	Missense	distal	-6	no	118.760	118.524	PhosphoSitePlus	COSMIC	98.777	Down-regulation
CMGC_DYRK_HIPK_HIPK2_ST	O15297	PPM1D	Q9H2X6	HIPK2	S85	A82V	82	Missense	distal	-3	no	118.760	118.984	PhosphoSitePlus	COSMIC	98.777	Up-regulation
CMGC_DYRK_HIPK_HIPK2_ST	O15297	PPM1D	Q9H2X6	HIPK2	T517	N512K	512	Missense	distal	-5	no	102.327	106.156	EPSD	COSMIC	98.777	Up-regulation
CMGC_DYRK_HIPK_HIPK2_ST	O15297	PPM1D	Q9H2X6	HIPK2	T517	P518S	518	Missense	proximal	1	no	102.327	85.046	EPSD	COSMIC	98.777	Loss
CMGC_DYRK_HIPK_HIPK2_ST	O15297	PPM1D	Q9H2X6	HIPK2	T517	M515V	515	Missense	proximal	-2	no	102.327	102.046	EPSD	COSMIC	98.777	Down-regulation
CMGC_DYRK_HIPK_HIPK2_ST	O15297	PPM1D	Q9H2X6	HIPK2	T529	P530S	530	Missense	proximal	1	no	112.788	95.508	EPSD	COSMIC	98.777	Loss
CMGC_DYRK_HIPK_HIPK2_ST	O15297	PPM1D	Q9H2X6	HIPK2	T529	I526M	526	Missense	distal	-3	no	112.788	112.881	EPSD	COSMIC;GDSC;CCLE	98.777	Up-regulation
CMGC_DYRK_HIPK_HIPK2_ST	O15297	PPM1D	Q9H2X6	HIPK2	S559	S558C	558	Missense	proximal	-1	no	104.541	101.144	EPSD	COSMIC	98.777	Down-regulation
CMGC_DYRK_HIPK_HIPK2_ST	O15297	PPM1D	Q9H2X6	HIPK2	S559	Q562K	562	Missense	distal	3	no	104.541	103.922	EPSD	COSMIC	98.777	Down-regulation
CMGC_DYRK_HIPK_HIPK2_ST	O15297	PPM1D	Q9H2X6	HIPK2	S559	A564P	564	Missense	distal	5	no	104.541	104.440	EPSD	COSMIC	98.777	Down-regulation
CMGC_DYRK_HIPK_HIPK2_ST	O15297	PPM1D	Q9H2X6	HIPK2	S559	L555S	555	Missense	distal	-4	no	104.541	104.545	EPSD	COSMIC	98.777	Up-regulation
CMGC_DYRK_HIPK_HIPK2_ST	Q96EB6	SIRT1	Q9H2X6	HIPK2	S14	S14P	14	Missense	central	0	yes	110.738	0.000	EPSD	COSMIC	98.777	Loss
CMGC_DYRK_HIPK_HIPK2_ST	Q96EB6	SIRT1	Q9H2X6	HIPK2	T530	E536V	536	Missense	distal	6	no	105.115	104.470	EPSD	COSMIC	98.777	Down-regulation
CMGC_DYRK_HIPK_HIPK2_ST	Q96EB6	SIRT1	Q9H2X6	HIPK2	S540	E542Q	542	Missense	proximal	2	no	106.061	105.420	EPSD	COSMIC	98.777	Down-regulation
CMGC_DYRK_HIPK_HIPK2_ST	Q96EB6	SIRT1	Q9H2X6	HIPK2	S540	E536V	536	Missense	distal	-4	no	106.061	105.781	EPSD	COSMIC	98.777	Down-regulation
CMGC_DYRK_HIPK_HIPK2_ST	Q96EB6	SIRT1	Q9H2X6	HIPK2	S545	E542Q	542	Missense	distal	-3	no	108.033	107.875	EPSD	COSMIC	98.777	Down-regulation
CMGC_DYRK_HIPK_HIPK2_ST	Q96EB6	SIRT1	Q9H2X6	HIPK2	S545	S549C	549	Missense	distal	4	no	108.033	98.814	EPSD	COSMIC	98.777	Down-regulation
CMGC_DYRK_HIPK_HIPK2_ST	Q96EB6	SIRT1	Q9H2X6	HIPK2	S682	E687K	687	Missense	distal	5	no	119.031	119.095	PhosphoSitePlus;EPSD	COSMIC;GDSC;CCLE	98.777	Up-regulation
CMGC_DYRK_HIPK_HIPK2_ST	Q9H2X6	HIPK2	Q9H2X6	HIPK2	S364	P370Q	370	Missense	distal	6	no	111.696	111.650	EPSD;PhosphoSitePlus	COSMIC	98.777	Down-regulation
CMGC_DYRK_HIPK_HIPK2_ST	Q9H2X6	HIPK2	Q9H2X6	HIPK2	S441	R447K	447	Missense	distal	6	no	106.073	106.455	EPSD	COSMIC	98.777	Up-regulation
CMGC_DYRK_HIPK_HIPK2_ST	Q9H2X6	HIPK2	Q9H2X6	HIPK2	S441	P444A	444	Missense	distal	3	no	106.073	105.636	EPSD	COSMIC	98.777	Down-regulation
CMGC_DYRK_HIPK_HIPK2_ST	Q9H2X6	HIPK2	Q9H2X6	HIPK2	T566	T560M	560	Missense	distal	-6	no	101.793	101.774	EPSD	COSMIC	98.777	Down-regulation
CMGC_DYRK_HIPK_HIPK2_ST	Q9H2X6	HIPK2	Q9H2X6	HIPK2	T566	V572M	572	Missense	distal	6	no	101.793	101.767	EPSD	COSMIC	98.777	Down-regulation
CMGC_DYRK_HIPK_HIPK2_ST	Q9H2X6	HIPK2	Q9H2X6	HIPK2	T566	P567F	567	Missense	proximal	1	no	101.793	44.440	EPSD	COSMIC	98.777	Loss
CMGC_DYRK_HIPK_HIPK2_ST	Q9H2X6	HIPK2	Q9H2X6	HIPK2	T566	I569V	569	Missense	distal	3	no	101.793	101.342	EPSD	COSMIC	98.777	Down-regulation
CMGC_DYRK_HIPK_HIPK2_ST	Q9H2X6	HIPK2	Q9H2X6	HIPK2	S668	A673T	673	Missense	distal	5	no	102.145	102.174	EPSD	COSMIC	98.777	Up-regulation
CMGC_DYRK_HIPK_HIPK2_ST	Q9H2X6	HIPK2	Q9H2X6	HIPK2	T838	R841W	841	Missense	distal	3	no	99.480	98.372	EPSD	COSMIC	98.777	Loss
CMGC_DYRK_HIPK_HIPK2_ST	Q9H2X6	HIPK2	Q9H2X6	HIPK2	T880	P883S	883	Missense	distal	3	no	121.162	121.474	PhosphoSitePlus;EPSD	COSMIC	98.777	Up-regulation
CMGC_DYRK_HIPK_HIPK2_ST	Q9H2X6	HIPK2	Q9H2X6	HIPK2	T880	T884K	884	Missense	distal	4	no	121.162	123.362	PhosphoSitePlus;EPSD	COSMIC	98.777	Up-regulation
CMGC_DYRK_HIPK_HIPK2_ST	Q9H2X6	HIPK2	Q9H2X6	HIPK2	T880	S882F	882	Missense	proximal	2	no	121.162	118.271	PhosphoSitePlus;EPSD	COSMIC	98.777	Down-regulation
CMGC_DYRK_HIPK_HIPK2_ST	Q9H2X6	HIPK2	Q9H2X6	HIPK2	S882	P883S	883	Missense	proximal	1	no	118.885	101.605	EPSD;PhosphoSitePlus	COSMIC	98.777	Down-regulation
CMGC_DYRK_HIPK_HIPK2_ST	Q9H2X6	HIPK2	Q9H2X6	HIPK2	S882	T884K	884	Missense	proximal	2	no	118.885	118.798	EPSD;PhosphoSitePlus	COSMIC	98.777	Down-regulation
CMGC_DYRK_HIPK_HIPK2_ST	Q9H2X6	HIPK2	Q9H2X6	HIPK2	S882	S882F	882	Missense	central	0	yes	118.885	0.000	EPSD;PhosphoSitePlus	COSMIC	98.777	Loss
CMGC_DYRK_HIPK_HIPK2_ST	Q9H2X6	HIPK2	Q9H2X6	HIPK2	S924	D923N	923	Missense	proximal	-1	no	102.872	102.788	EPSD	COSMIC	98.777	Down-regulation
CMGC_DYRK_HIPK_HIPK2_ST	Q9H2X6	HIPK2	Q9H2X6	HIPK2	S924	Y926H	926	Missense	proximal	2	no	102.872	101.539	EPSD	COSMIC	98.777	Down-regulation
CMGC_DYRK_HIPK_HIPK2_ST	Q9H2X6	HIPK2	Q9H2X6	HIPK2	S934	V938L	938	Missense	distal	4	no	105.408	107.259	EPSD	COSMIC;CCLE	98.777	Up-regulation
CMGC_DYRK_HIPK_HIPK2_ST	Q9H2X6	HIPK2	Q9H2X6	HIPK2	S1014	G1011C	1011	Missense	distal	-3	no	103.648	104.593	EPSD	COSMIC	98.777	Up-regulation
CMGC_DYRK_HIPK_HIPK2_ST	Q9H2X6	HIPK2	Q9H2X6	HIPK2	S1014	S1014R	1014	Missense	central	0	yes	103.648	0.000	EPSD	COSMIC	98.777	Loss
CMGC_DYRK_HIPK_HIPK2_ST	Q9H2X6	HIPK2	Q9H2X6	HIPK2	S1018	G1011C	1011	Missense	distal	-7	no	103.681	100.584	EPSD	COSMIC	98.777	Down-regulation
CMGC_DYRK_HIPK_HIPK2_ST	Q9H2X6	HIPK2	Q9H2X6	HIPK2	S1018	S1014R	1014	Missense	distal	-4	no	103.681	103.556	EPSD	COSMIC	98.777	Down-regulation
CMGC_DYRK_HIPK_HIPK2_ST	Q9H2X6	HIPK2	Q9H2X6	HIPK2	S1018	R1024C	1024	Missense	distal	6	no	103.681	103.213	EPSD	COSMIC	98.777	Down-regulation
CMGC_DYRK_HIPK_HIPK2_ST	Q9H2X6	HIPK2	Q9H2X6	HIPK2	T1114	V1121A	1121	Missense	distal	7	no	99.866	100.193	EPSD	COSMIC;GDSC;CCLE	98.777	Up-regulation
CMGC_DYRK_HIPK_HIPK2_ST	Q9H2X6	HIPK2	Q9H2X6	HIPK2	T1114	V1117D	1117	Missense	distal	3	no	99.866	99.875	EPSD	COSMIC	98.777	Up-regulation
CMGC_DYRK_HIPK_HIPK2_ST	P46527	CDKN1B	Q9H2X6	HIPK2	S10	R5L	5	Missense	distal	-5	no	103.610	97.969	PhosphoSitePlus	COSMIC	98.777	Loss
CMGC_DYRK_HIPK_HIPK2_ST	P46527	CDKN1B	Q9H2X6	HIPK2	S10	E14K	14	Missense	distal	4	no	103.610	104.088	PhosphoSitePlus	COSMIC	98.777	Up-regulation
CMGC_DYRK_HIPK_HIPK2_ST	P46527	CDKN1B	Q9H2X6	HIPK2	S10	M16T	16	Missense	distal	6	no	103.610	103.876	PhosphoSitePlus	COSMIC	98.777	Up-regulation
CMGC_DYRK_HIPK_HIPK2_ST	P46527	CDKN1B	Q9H2X6	HIPK2	S10	N3D	3	Missense	distal	-7	no	103.610	103.475	PhosphoSitePlus	COSMIC	98.777	Down-regulation
CMGC_DYRK_HIPK_HIPK2_ST	P46527	CDKN1B	Q9H2X6	HIPK2	S10	P11S	11	Missense	proximal	1	no	103.610	86.330	PhosphoSitePlus	COSMIC	98.777	Loss
CMGC_DYRK_HIPK_HIPK2_ST	P46527	CDKN1B	Q9H2X6	HIPK2	S10	S12N	12	Missense	proximal	2	no	103.610	102.823	PhosphoSitePlus	COSMIC	98.777	Down-regulation
CMGC_DYRK_HIPK_HIPK2_ST	P46527	CDKN1B	Q9H2X6	HIPK2	S10	D17E	17	Missense	distal	7	no	103.610	103.934	PhosphoSitePlus	COSMIC	98.777	Up-regulation
CMGC_DYRK_HIPK_HIPK2_ST	P46527	CDKN1B	Q9H2X6	HIPK2	S106	Q107R	107	Missense	proximal	1	no	60.231	99.790	EPSD	COSMIC	98.777	Gain
CMGC_DYRK_HIPK_HIPK2_ST	P46527	CDKN1B	Q9H2X6	HIPK2	S110	Q107R	107	Missense	distal	-3	no	108.233	108.797	EPSD	COSMIC	98.777	Up-regulation
CMGC_DYRK_HIPK_HIPK2_ST	P46527	CDKN1B	Q9H2X6	HIPK2	S110	D108N	108	Missense	proximal	-2	no	108.233	108.306	EPSD	COSMIC	98.777	Up-regulation
CMGC_DYRK_HIPK_HIPK2_ST	P46527	CDKN1B	Q9H2X6	HIPK2	S110	A116T	116	Missense	distal	6	no	108.233	108.106	EPSD	COSMIC	98.777	Down-regulation
CMGC_DYRK_HIPK_HIPK2_ST	P46527	CDKN1B	Q9H2X6	HIPK2	S112	Q107R	107	Missense	distal	-5	no	103.876	104.469	EPSD	COSMIC	98.777	Up-regulation
CMGC_DYRK_HIPK_HIPK2_ST	P46527	CDKN1B	Q9H2X6	HIPK2	S112	D108N	108	Missense	distal	-4	no	103.876	103.825	EPSD	COSMIC	98.777	Down-regulation
CMGC_DYRK_HIPK_HIPK2_ST	P46527	CDKN1B	Q9H2X6	HIPK2	S112	A116T	116	Missense	distal	4	no	103.876	103.120	EPSD	COSMIC	98.777	Down-regulation
CMGC_DYRK_HIPK_HIPK2_ST	P46527	CDKN1B	Q9H2X6	HIPK2	T135	D136G	136	Missense	proximal	1	no	84.805	101.231	EPSD	COSMIC;GDSC	98.777	Gain
CMGC_DYRK_HIPK_HIPK2_ST	P46527	CDKN1B	Q9H2X6	HIPK2	T142	C148Y	148	Missense	distal	6	no	108.563	109.058	EPSD	COSMIC	98.777	Up-regulation
CMGC_DYRK_HIPK_HIPK2_ST	P46527	CDKN1B	Q9H2X6	HIPK2	T142	A149T	149	Missense	distal	7	no	108.563	108.656	EPSD	COSMIC	98.777	Up-regulation
CMGC_DYRK_HIPK_HIPK2_ST	P46527	CDKN1B	Q9H2X6	HIPK2	T142	P137S	137	Missense	distal	-5	no	108.563	104.301	EPSD	COSMIC	98.777	Down-regulation
CMGC_DYRK_HIPK_HIPK2_ST	P46527	CDKN1B	Q9H2X6	HIPK2	T142	S140R	140	Missense	proximal	-2	no	108.563	108.241	EPSD	COSMIC	98.777	Down-regulation
CMGC_DYRK_HIPK_HIPK2_ST	P46527	CDKN1B	Q9H2X6	HIPK2	T142	D136G	136	Missense	distal	-6	no	108.563	108.450	EPSD	COSMIC;GDSC	98.777	Down-regulation
CMGC_DYRK_HIPK_HIPK2_ST	P46527	CDKN1B	Q9H2X6	HIPK2	T142	E146V	146	Missense	distal	4	no	108.563	104.614	EPSD	COSMIC	98.777	Down-regulation
CMGC_DYRK_HIPK_HIPK2_ST	P46527	CDKN1B	Q9H2X6	HIPK2	S178	V184L	184	Missense	distal	6	no	99.666	99.715	EPSD	COSMIC	98.777	Up-regulation
CMGC_DYRK_HIPK_HIPK2_ST	P46527	CDKN1B	Q9H2X6	HIPK2	S178	G182D	182	Missense	distal	4	no	99.666	96.743	EPSD	COSMIC	98.777	Loss
CMGC_DYRK_HIPK_HIPK2_ST	O00257	CBX4	Q9H2X6	HIPK2	S99	S100P	100	Missense	proximal	1	no	82.162	99.442	EPSD	COSMIC	98.777	Gain
CMGC_DYRK_HIPK_HIPK2_ST	O00257	CBX4	Q9H2X6	HIPK2	S147	Q153E	153	Missense	distal	6	no	102.564	102.833	EPSD	COSMIC	98.777	Up-regulation
CMGC_DYRK_HIPK_HIPK2_ST	O00257	CBX4	Q9H2X6	HIPK2	S291	A285S	285	Missense	distal	-6	no	111.295	111.435	EPSD	COSMIC	98.777	Up-regulation
CMGC_DYRK_HIPK_HIPK2_ST	O00257	CBX4	Q9H2X6	HIPK2	S291	P292S	292	Missense	proximal	1	no	111.295	94.015	EPSD	COSMIC	98.777	Loss
CMGC_DYRK_HIPK_HIPK2_ST	O00257	CBX4	Q9H2X6	HIPK2	S333	S336R	336	Missense	distal	3	no	103.909	103.519	EPSD	COSMIC	98.777	Down-regulation
CMGC_DYRK_HIPK_HIPK2_ST	O00257	CBX4	Q9H2X6	HIPK2	S333	R328W	328	Missense	distal	-5	no	103.909	88.611	EPSD	COSMIC	98.777	Loss
CMGC_DYRK_HIPK_HIPK2_ST	O00257	CBX4	Q9H2X6	HIPK2	S345	R346L	346	Missense	proximal	1	no	104.813	-2.935	EPSD	COSMIC	98.777	Loss
CMGC_DYRK_HIPK_HIPK2_ST	O00257	CBX4	Q9H2X6	HIPK2	S349	R346L	346	Missense	distal	-3	no	110.746	110.815	EPSD	COSMIC	98.777	Up-regulation
CMGC_DYRK_HIPK_HIPK2_ST	O00257	CBX4	Q9H2X6	HIPK2	T435	A430V	430	Missense	distal	-5	no	102.901	105.448	EPSD	COSMIC	98.777	Up-regulation
CMGC_DYRK_HIPK_HIPK2_ST	O00257	CBX4	Q9H2X6	HIPK2	T497	S500L	500	Missense	distal	3	no	120.888	120.352	PhosphoSitePlus	COSMIC	98.777	Down-regulation
CMGC_DYRK_HIPK_HIPK2_ST	O00257	CBX4	Q9H2X6	HIPK2	T497	A501V	501	Missense	distal	4	no	120.888	117.905	PhosphoSitePlus	COSMIC	98.777	Down-regulation
CMGC_DYRK_HIPK_HIPK2_ST	O00257	CBX4	Q9H2X6	HIPK2	T497	S500A	500	Missense	distal	3	no	120.888	120.139	PhosphoSitePlus	COSMIC	98.777	Down-regulation
CMGC_DYRK_HIPK_HIPK2_ST	P16220	CREB1	Q9H2X6	HIPK2	S129	R124Q	124	Missense	distal	-5	no	101.576	100.983	EPSD	COSMIC	98.777	Down-regulation
CMGC_DYRK_HIPK_HIPK2_ST	P16220	CREB1	Q9H2X6	HIPK2	S129	R125T	125	Missense	distal	-4	no	101.576	101.704	EPSD	COSMIC	98.777	Up-regulation
CMGC_DYRK_HIPK_HIPK2_ST	P16220	CREB1	Q9H2X6	HIPK2	S129	L128R	128	Missense	proximal	-1	no	101.576	101.755	EPSD	COSMIC	98.777	Up-regulation
CMGC_DYRK_HIPK_HIPK2_ST	P16220	CREB1	Q9H2X6	HIPK2	S271	A269T	269	Missense	proximal	-2	no	119.256	119.037	PhosphoSitePlus	COSMIC	98.777	Down-regulation
CMGC_DYRK_HIPK_HIPK2_ST	P16220	CREB1	Q9H2X6	HIPK2	S271	P264T	264	Missense	distal	-7	no	119.256	117.948	PhosphoSitePlus	COSMIC;GDSC;CCLE	98.777	Down-regulation
CMGC_DYRK_HIPK_HIPK2_ST	O43255	SIAH2	Q9H2X6	HIPK2	T26	S28F	28	Missense	proximal	2	no	108.102	105.211	EPSD	COSMIC	98.777	Down-regulation
CMGC_DYRK_HIPK_HIPK2_ST	O43255	SIAH2	Q9H2X6	HIPK2	T26	P27R	27	Missense	proximal	1	no	108.102	95.566	EPSD	COSMIC	98.777	Loss
CMGC_DYRK_HIPK_HIPK2_ST	O43255	SIAH2	Q9H2X6	HIPK2	S28	S28F	28	Missense	central	0	yes	121.929	0.000	PhosphoSitePlus	COSMIC	98.777	Loss
CMGC_DYRK_HIPK_HIPK2_ST	O43255	SIAH2	Q9H2X6	HIPK2	S28	P27R	27	Missense	proximal	-1	no	121.929	120.718	PhosphoSitePlus	COSMIC	98.777	Down-regulation
CMGC_DYRK_HIPK_HIPK2_ST	O43255	SIAH2	Q9H2X6	HIPK2	T254	I248N	248	Missense	distal	-6	no	100.699	100.609	EPSD	COSMIC;GDSC;CCLE	98.777	Down-regulation
CMGC_DYRK_HIPK_HIPK2_ST	Q9H3D4	TP63	Q9H2X6	HIPK2	S160	P161S	161	Missense	proximal	1	no	104.093	86.812	EPSD	COSMIC	98.777	Loss
CMGC_DYRK_HIPK_HIPK2_ST	Q9H3D4	TP63	Q9H2X6	HIPK2	S160	L159F	159	Missense	proximal	-1	no	104.093	103.537	EPSD	COSMIC	98.777	Down-regulation
CMGC_DYRK_HIPK_HIPK2_ST	Q9H3D4	TP63	Q9H2X6	HIPK2	S160	S160C	160	Missense	central	0	yes	104.093	0.000	EPSD	COSMIC	98.777	Loss
CMGC_DYRK_HIPK_HIPK2_ST	Q9H3D4	TP63	Q9H2X6	HIPK2	S160	S154C	154	Missense	distal	-6	no	104.093	103.517	EPSD	COSMIC;CCLE	98.777	Down-regulation
CMGC_DYRK_HIPK_HIPK2_ST	Q9H3D4	TP63	Q9H2X6	HIPK2	S160	S153I	153	Missense	distal	-7	no	104.093	103.849	EPSD	COSMIC	98.777	Down-regulation
CMGC_DYRK_HIPK_HIPK2_ST	Q9H3D4	TP63	Q9H2X6	HIPK2	S160	P166H	166	Missense	distal	6	no	104.093	103.245	EPSD	COSMIC	98.777	Down-regulation
CMGC_DYRK_HIPK_HIPK2_ST	Q9H3D4	TP63	Q9H2X6	HIPK2	S160	P161L	161	Missense	proximal	1	no	104.093	-16.192	EPSD	COSMIC	98.777	Loss
CMGC_DYRK_HIPK_HIPK2_ST	Q9H3D4	TP63	Q9H2X6	HIPK2	S162	T169N	169	Missense	distal	7	no	117.768	117.580	EPSD	COSMIC	98.777	Down-regulation
CMGC_DYRK_HIPK_HIPK2_ST	Q9H3D4	TP63	Q9H2X6	HIPK2	S162	P161S	161	Missense	proximal	-1	no	117.768	118.085	EPSD	COSMIC	98.777	Up-regulation
CMGC_DYRK_HIPK_HIPK2_ST	Q9H3D4	TP63	Q9H2X6	HIPK2	S162	L159F	159	Missense	distal	-3	no	117.768	118.085	EPSD	COSMIC	98.777	Up-regulation
CMGC_DYRK_HIPK_HIPK2_ST	Q9H3D4	TP63	Q9H2X6	HIPK2	S162	S160C	160	Missense	proximal	-2	no	117.768	116.747	EPSD	COSMIC	98.777	Down-regulation
CMGC_DYRK_HIPK_HIPK2_ST	Q9H3D4	TP63	Q9H2X6	HIPK2	S162	T169I	169	Missense	distal	7	no	117.768	117.494	EPSD	COSMIC	98.777	Down-regulation
CMGC_DYRK_HIPK_HIPK2_ST	Q9H3D4	TP63	Q9H2X6	HIPK2	S162	P166H	166	Missense	distal	4	no	117.768	112.365	EPSD	COSMIC	98.777	Down-regulation
CMGC_DYRK_HIPK_HIPK2_ST	Q9H3D4	TP63	Q9H2X6	HIPK2	S162	N168S	168	Missense	distal	6	no	117.768	117.927	EPSD	COSMIC	98.777	Up-regulation
CMGC_DYRK_HIPK_HIPK2_ST	Q9H3D4	TP63	Q9H2X6	HIPK2	S162	P161L	161	Missense	proximal	-1	no	117.768	116.378	EPSD	COSMIC	98.777	Down-regulation
CMGC_DYRK_HIPK_HIPK2_ST	Q9H3D4	TP63	Q9H2X6	HIPK2	T368	K369R	369	Missense	proximal	1	no	97.353	107.709	EPSD	COSMIC	98.777	Gain
CMGC_DYRK_HIPK_HIPK2_ST	Q9H3D4	TP63	Q9H2X6	HIPK2	S395	K392E	392	Missense	distal	-3	no	106.730	106.731	EPSD	COSMIC	98.777	Up-regulation
CMGC_DYRK_HIPK_HIPK2_ST	Q9H3D4	TP63	Q9H2X6	HIPK2	S395	S395F	395	Missense	central	0	yes	106.730	0.000	EPSD	COSMIC;GDSC	98.777	Loss
CMGC_DYRK_HIPK_HIPK2_ST	Q9H3D4	TP63	Q9H2X6	HIPK2	S455	S462L	462	Missense	distal	7	no	108.088	107.870	EPSD	COSMIC	98.777	Down-regulation
CMGC_DYRK_HIPK_HIPK2_ST	Q9H3D4	TP63	Q9H2X6	HIPK2	S455	S462A	462	Missense	distal	7	no	108.088	107.957	EPSD	COSMIC	98.777	Down-regulation
CMGC_DYRK_HIPK_HIPK2_ST	Q9H3D4	TP63	Q9H2X6	HIPK2	S455	Q454H	454	Missense	proximal	-1	no	108.088	105.759	EPSD	COSMIC	98.777	Down-regulation
CMGC_DYRK_HIPK_HIPK2_ST	Q9H3D4	TP63	Q9H2X6	HIPK2	S455	Q454R	454	Missense	proximal	-1	no	108.088	107.049	EPSD	COSMIC	98.777	Down-regulation
CMGC_DYRK_HIPK_HIPK2_ST	Q9H3D4	TP63	Q9H2X6	HIPK2	S455	Q450R	450	Missense	distal	-5	no	108.088	108.681	EPSD	COSMIC	98.777	Up-regulation
CMGC_DYRK_HIPK_HIPK2_ST	Q9H3D4	TP63	Q9H2X6	HIPK2	S455	Q450H	450	Missense	distal	-5	no	108.088	97.846	EPSD	COSMIC	98.777	Loss
CMGC_DYRK_HIPK_HIPK2_ST	Q9H3D4	TP63	Q9H2X6	HIPK2	S455	S457G	457	Missense	proximal	2	no	108.088	107.120	EPSD	COSMIC	98.777	Down-regulation
CMGC_DYRK_HIPK_HIPK2_ST	Q9H3D4	TP63	Q9H2X6	HIPK2	S463	S462L	462	Missense	proximal	-1	no	109.982	108.275	EPSD	COSMIC	98.777	Down-regulation
CMGC_DYRK_HIPK_HIPK2_ST	Q9H3D4	TP63	Q9H2X6	HIPK2	S463	S462A	462	Missense	proximal	-1	no	109.982	108.908	EPSD	COSMIC	98.777	Down-regulation
CMGC_DYRK_HIPK_HIPK2_ST	Q9H3D4	TP63	Q9H2X6	HIPK2	S463	N467K	467	Missense	distal	4	no	109.982	113.112	EPSD	COSMIC	98.777	Up-regulation
CMGC_DYRK_HIPK_HIPK2_ST	Q9H3D4	TP63	Q9H2X6	HIPK2	S463	N470S	470	Missense	distal	7	no	109.982	110.209	EPSD	COSMIC;GDSC;CCLE	98.777	Up-regulation
CMGC_DYRK_HIPK_HIPK2_ST	Q9H3D4	TP63	Q9H2X6	HIPK2	S463	S457G	457	Missense	distal	-6	no	109.982	109.854	EPSD	COSMIC	98.777	Down-regulation
CMGC_DYRK_HIPK_HIPK2_ST	Q9H3D4	TP63	Q9H2X6	HIPK2	T491	P492H	492	Missense	proximal	1	no	114.097	2.043	PhosphoSitePlus	COSMIC	98.777	Loss
CMGC_DYRK_HIPK_HIPK2_ST	Q9H3D4	TP63	Q9H2X6	HIPK2	T491	P484H	484	Missense	distal	-7	no	114.097	110.873	PhosphoSitePlus	COSMIC	98.777	Down-regulation
CMGC_DYRK_HIPK_HIPK2_ST	Q9H3D4	TP63	Q9H2X6	HIPK2	T491	T494A	494	Missense	distal	3	no	114.097	114.124	PhosphoSitePlus	COSMIC	98.777	Up-regulation
CMGC_DYRK_HIPK_HIPK2_ST	Q9H3D4	TP63	Q9H2X6	HIPK2	T491	I495M	495	Missense	distal	4	no	114.097	112.938	PhosphoSitePlus	COSMIC	98.777	Down-regulation
CMGC_DYRK_HIPK_HIPK2_ST	Q9H3D4	TP63	Q9H2X6	HIPK2	T491	P492T	492	Missense	proximal	1	no	114.097	-37.238	PhosphoSitePlus	COSMIC	98.777	Loss
CMGC_DYRK_HIPK_HIPK2_ST	Q9H3D4	TP63	Q9H2X6	HIPK2	T491	D497N	497	Missense	distal	6	no	114.097	114.111	PhosphoSitePlus	COSMIC	98.777	Up-regulation
CMGC_DYRK_HIPK_HIPK2_ST	Q9H3D4	TP63	Q9H2X6	HIPK2	T491	L490R	490	Missense	proximal	-1	no	114.097	114.276	PhosphoSitePlus	COSMIC	98.777	Up-regulation
CMGC_DYRK_HIPK_HIPK2_ST	Q9H3D4	TP63	Q9H2X6	HIPK2	T491	P496H	496	Missense	distal	5	no	114.097	114.349	PhosphoSitePlus	COSMIC	98.777	Up-regulation
CMGC_DYRK_HIPK_HIPK2_ST	Q9H3D4	TP63	Q9H2X6	HIPK2	S612	R618W	618	Missense	distal	6	no	99.370	98.732	EPSD	COSMIC;GDSC;CCLE	98.777	Loss
CMGC_DYRK_HIPK_HIPK2_ST	Q9H3D4	TP63	Q9H2X6	HIPK2	S612	R605Q	605	Missense	distal	-7	no	99.370	100.496	EPSD	COSMIC;GDSC	98.777	Up-regulation
CMGC_DYRK_HIPK_HIPK2_ST	Q9H3D4	TP63	Q9H2X6	HIPK2	S612	R618Q	618	Missense	distal	6	no	99.370	99.853	EPSD	COSMIC	98.777	Up-regulation
CMGC_DYRK_HIPK_HIPK2_ST	Q9H3D4	TP63	Q9H2X6	HIPK2	S612	R605W	605	Missense	distal	-7	no	99.370	96.068	EPSD	COSMIC	98.777	Loss
CMGC_DYRK_HIPK_HIPK2_ST	Q9H3D4	TP63	Q9H2X6	HIPK2	S612	S612F	612	Missense	central	0	yes	99.370	0.000	EPSD	COSMIC	98.777	Loss
CMGC_DYRK_HIPK_HIPK2_ST	Q9H3D4	TP63	Q9H2X6	HIPK2	S612	P613L	613	Missense	proximal	1	no	99.370	-20.915	EPSD	COSMIC	98.777	Loss
CMGC_DYRK_HIPK_HIPK2_ST	Q9H3D4	TP63	Q9H2X6	HIPK2	S612	H615D	615	Missense	distal	3	no	99.370	99.482	EPSD	COSMIC	98.777	Up-regulation
CMGC_DYRK_HIPK_HIPK2_ST	Q9H3D4	TP63	Q9H2X6	HIPK2	S612	P613T	613	Missense	proximal	1	no	99.370	-51.965	EPSD	COSMIC	98.777	Loss
CMGC_DYRK_HIPK_HIPK2_ST	Q9H3D4	TP63	Q9H2X6	HIPK2	S612	H608Q	608	Missense	distal	-4	no	99.370	99.753	EPSD	COSMIC	98.777	Up-regulation
CMGC_DYRK_HIPK_HIPK2_ST	Q9H3D4	TP63	Q9H2X6	HIPK2	T619	V626F	626	Missense	distal	7	no	110.853	110.752	EPSD	COSMIC	98.777	Down-regulation
CMGC_DYRK_HIPK_HIPK2_ST	Q9H3D4	TP63	Q9H2X6	HIPK2	T619	R618W	618	Missense	proximal	-1	no	110.853	108.382	EPSD	COSMIC;GDSC;CCLE	98.777	Down-regulation
CMGC_DYRK_HIPK_HIPK2_ST	Q9H3D4	TP63	Q9H2X6	HIPK2	T619	R618Q	618	Missense	proximal	-1	no	110.853	111.891	EPSD	COSMIC	98.777	Up-regulation
CMGC_DYRK_HIPK_HIPK2_ST	Q9H3D4	TP63	Q9H2X6	HIPK2	T619	S622I	622	Missense	distal	3	no	110.853	110.528	EPSD	COSMIC	98.777	Down-regulation
CMGC_DYRK_HIPK_HIPK2_ST	Q9H3D4	TP63	Q9H2X6	HIPK2	T619	S612F	612	Missense	distal	-7	no	110.853	108.911	EPSD	COSMIC	98.777	Down-regulation
CMGC_DYRK_HIPK_HIPK2_ST	Q9H3D4	TP63	Q9H2X6	HIPK2	T619	P613L	613	Missense	distal	-6	no	110.853	110.717	EPSD	COSMIC	98.777	Down-regulation
CMGC_DYRK_HIPK_HIPK2_ST	Q9H3D4	TP63	Q9H2X6	HIPK2	T619	H615D	615	Missense	distal	-4	no	110.853	111.209	EPSD	COSMIC	98.777	Up-regulation
CMGC_DYRK_HIPK_HIPK2_ST	Q9H3D4	TP63	Q9H2X6	HIPK2	T619	P613T	613	Missense	distal	-6	no	110.853	110.586	EPSD	COSMIC	98.777	Down-regulation
CMGC_DYRK_HIPK_HIPK2_ST	P17676	CEBPB	Q9H2X6	HIPK2	S76	H69Q	69	Missense	distal	-7	no	104.351	107.818	EPSD	COSMIC	98.777	Up-regulation
Atypical_PIKK_FRAP_MTOR_ST	Q8N122	RPTOR	P42345	MTOR	S696	E689K	689	Missense	distal	-7	no	11.129	10.920	EPSD	COSMIC	6.822	Down-regulation
Atypical_PIKK_FRAP_MTOR_ST	Q8N122	RPTOR	P42345	MTOR	S696	S696Y	696	Missense	central	0	yes	11.129	0.000	EPSD	COSMIC	6.822	Loss
Atypical_PIKK_FRAP_MTOR_ST	Q8N122	RPTOR	P42345	MTOR	S696	A693T	693	Missense	distal	-3	no	11.129	11.183	EPSD	COSMIC;GDSC;CCLE	6.822	Up-regulation
Atypical_PIKK_FRAP_MTOR_ST	Q8N122	RPTOR	P42345	MTOR	S696	G702E	702	Missense	distal	6	no	11.129	11.367	EPSD	COSMIC	6.822	Up-regulation
Atypical_PIKK_FRAP_MTOR_ST	Q8N122	RPTOR	P42345	MTOR	S696	S696A	696	Missense	central	0	yes	11.129	0.000	EPSD	COSMIC	6.822	Loss
Atypical_PIKK_FRAP_MTOR_ST	Q8N122	RPTOR	P42345	MTOR	S704	D710N	710	Missense	distal	6	no	10.835	9.885	EPSD	COSMIC	6.822	Down-regulation
Atypical_PIKK_FRAP_MTOR_ST	Q8N122	RPTOR	P42345	MTOR	S704	R709G	709	Missense	distal	5	no	10.835	10.505	EPSD	COSMIC	6.822	Down-regulation
Atypical_PIKK_FRAP_MTOR_ST	Q8N122	RPTOR	P42345	MTOR	S704	G702E	702	Missense	proximal	-2	no	10.835	10.195	EPSD	COSMIC	6.822	Down-regulation
Atypical_PIKK_FRAP_MTOR_ST	Q8N122	RPTOR	P42345	MTOR	T706	P712L	712	Missense	distal	6	no	8.436	7.277	EPSD	COSMIC	6.822	Down-regulation
Atypical_PIKK_FRAP_MTOR_ST	Q8N122	RPTOR	P42345	MTOR	T706	D710N	710	Missense	distal	4	no	8.436	8.033	EPSD	COSMIC	6.822	Down-regulation
Atypical_PIKK_FRAP_MTOR_ST	Q8N122	RPTOR	P42345	MTOR	T706	R709G	709	Missense	distal	3	no	8.436	9.784	EPSD	COSMIC	6.822	Up-regulation
Atypical_PIKK_FRAP_MTOR_ST	Q8N122	RPTOR	P42345	MTOR	T706	G702E	702	Missense	distal	-4	no	8.436	8.882	EPSD	COSMIC	6.822	Up-regulation
Atypical_PIKK_FRAP_MTOR_ST	Q8N122	RPTOR	P42345	MTOR	S767	A765T	765	Missense	proximal	-2	no	7.014	6.517	EPSD	COSMIC	6.822	Loss
Atypical_PIKK_FRAP_MTOR_ST	Q8N122	RPTOR	P42345	MTOR	S767	S766T	766	Missense	proximal	-1	no	7.014	6.960	EPSD	COSMIC	6.822	Down-regulation
Atypical_PIKK_FRAP_MTOR_ST	Q8N122	RPTOR	P42345	MTOR	S771	A765T	765	Missense	distal	-6	no	8.513	8.792	EPSD	COSMIC	6.822	Up-regulation
Atypical_PIKK_FRAP_MTOR_ST	Q8N122	RPTOR	P42345	MTOR	S771	E775Q	775	Missense	distal	4	no	8.513	8.303	EPSD	COSMIC	6.822	Down-regulation
Atypical_PIKK_FRAP_MTOR_ST	Q8N122	RPTOR	P42345	MTOR	S771	S766T	766	Missense	distal	-5	no	8.513	8.519	EPSD	COSMIC	6.822	Up-regulation
Atypical_PIKK_FRAP_MTOR_ST	Q8N122	RPTOR	P42345	MTOR	S795	R789H	789	Missense	distal	-6	no	8.024	7.218	EPSD	COSMIC;GDSC;CCLE	6.822	Down-regulation
Atypical_PIKK_FRAP_MTOR_ST	Q8N122	RPTOR	P42345	MTOR	S795	R788C	788	Missense	distal	-7	no	8.024	6.929	EPSD	COSMIC;GDSC;CCLE	6.822	Down-regulation
Atypical_PIKK_FRAP_MTOR_ST	Q8N122	RPTOR	P42345	MTOR	S795	L796I	796	Missense	proximal	1	no	8.024	8.935	EPSD	COSMIC	6.822	Up-regulation
Atypical_PIKK_FRAP_MTOR_ST	Q8N122	RPTOR	P42345	MTOR	S795	R788H	788	Missense	distal	-7	no	8.024	7.675	EPSD	COSMIC	6.822	Down-regulation
Atypical_PIKK_FRAP_MTOR_ST	Q8N122	RPTOR	P42345	MTOR	S795	S798F	798	Missense	distal	3	no	8.024	8.429	EPSD	COSMIC	6.822	Up-regulation
Atypical_PIKK_FRAP_MTOR_ST	Q8N122	RPTOR	P42345	MTOR	S795	S792F	792	Missense	distal	-3	no	8.024	8.095	EPSD	COSMIC	6.822	Up-regulation
Atypical_PIKK_FRAP_MTOR_ST	Q8N122	RPTOR	P42345	MTOR	S795	A790S	790	Missense	distal	-5	no	8.024	7.997	EPSD	COSMIC	6.822	Down-regulation
Atypical_PIKK_FRAP_MTOR_ST	Q8N122	RPTOR	P42345	MTOR	S795	L799H	799	Missense	distal	4	no	8.024	7.832	EPSD	COSMIC	6.822	Down-regulation
Atypical_PIKK_FRAP_MTOR_ST	Q8N122	RPTOR	P42345	MTOR	S863	K867R	867	Missense	distal	4	no	10.953	10.650	EPSD;PhosphoSitePlus	COSMIC	6.822	Down-regulation
Atypical_PIKK_FRAP_MTOR_ST	Q8N122	RPTOR	P42345	MTOR	S863	G868S	868	Missense	distal	5	no	10.953	10.290	EPSD;PhosphoSitePlus	COSMIC	6.822	Down-regulation
Atypical_PIKK_FRAP_MTOR_ST	Q8N122	RPTOR	P42345	MTOR	S863	P861L	861	Missense	proximal	-2	no	10.953	10.462	EPSD;PhosphoSitePlus	COSMIC	6.822	Down-regulation
Atypical_PIKK_FRAP_MTOR_ST	Q8N122	RPTOR	P42345	MTOR	S863	V869M	869	Missense	distal	6	no	10.953	9.528	EPSD;PhosphoSitePlus	COSMIC	6.822	Down-regulation
Atypical_PIKK_FRAP_MTOR_ST	Q8N122	RPTOR	P42345	MTOR	S863	A862T	862	Missense	proximal	-1	no	10.953	10.904	EPSD;PhosphoSitePlus	COSMIC	6.822	Down-regulation
Atypical_PIKK_FRAP_MTOR_ST	Q8N122	RPTOR	P42345	MTOR	S877	A874V	874	Missense	distal	-3	no	10.049	10.679	EPSD	COSMIC;GDSC;CCLE	6.822	Up-regulation
Atypical_PIKK_FRAP_MTOR_ST	Q8N122	RPTOR	P42345	MTOR	S877	P878S	878	Missense	proximal	1	no	10.049	1.525	EPSD	COSMIC	6.822	Loss
Atypical_PIKK_FRAP_MTOR_ST	Q8N122	RPTOR	P42345	MTOR	S877	P879S	879	Missense	proximal	2	no	10.049	9.554	EPSD	COSMIC	6.822	Down-regulation
Atypical_PIKK_FRAP_MTOR_ST	Q8N122	RPTOR	P42345	MTOR	S877	A880S	880	Missense	distal	3	no	10.049	8.994	EPSD	COSMIC	6.822	Down-regulation
Atypical_PIKK_FRAP_MTOR_ST	Q8N122	RPTOR	P42345	MTOR	S877	P878L	878	Missense	proximal	1	no	10.049	4.080	EPSD	COSMIC	6.822	Loss
Atypical_PIKK_FRAP_MTOR_ST	Q8N122	RPTOR	P42345	MTOR	S882	T889A	889	Missense	distal	7	no	7.315	7.836	EPSD	COSMIC	6.822	Up-regulation
Atypical_PIKK_FRAP_MTOR_ST	Q8N122	RPTOR	P42345	MTOR	S882	P878S	878	Missense	distal	-4	no	7.315	7.444	EPSD	COSMIC	6.822	Up-regulation
Atypical_PIKK_FRAP_MTOR_ST	Q8N122	RPTOR	P42345	MTOR	S882	P879S	879	Missense	distal	-3	no	7.315	7.748	EPSD	COSMIC	6.822	Up-regulation
Atypical_PIKK_FRAP_MTOR_ST	Q8N122	RPTOR	P42345	MTOR	S882	A880S	880	Missense	proximal	-2	no	7.315	6.754	EPSD	COSMIC	6.822	Loss
Atypical_PIKK_FRAP_MTOR_ST	Q8N122	RPTOR	P42345	MTOR	S882	P878L	878	Missense	distal	-4	no	7.315	7.129	EPSD	COSMIC	6.822	Down-regulation
Atypical_PIKK_FRAP_MTOR_ST	Q13541	EIF4EBP1	P42345	MTOR	S65	L59Q	59	Missense	distal	-6	no	9.149	9.746	PhosphoSitePlus;EPSD	COSMIC	6.822	Up-regulation
Atypical_PIKK_FRAP_MTOR_ST	Q13541	EIF4EBP1	P42345	MTOR	S65	M60I	60	Missense	distal	-5	no	9.149	9.220	PhosphoSitePlus;EPSD	COSMIC	6.822	Up-regulation
Atypical_PIKK_FRAP_MTOR_ST	Q13541	EIF4EBP1	P42345	MTOR	S65	P72S	72	Missense	distal	7	no	9.149	9.128	PhosphoSitePlus;EPSD	COSMIC	6.822	Down-regulation
Atypical_PIKK_FRAP_MTOR_ST	Q13541	EIF4EBP1	P42345	MTOR	S65	R63W	63	Missense	proximal	-2	no	9.149	8.850	PhosphoSitePlus;EPSD	COSMIC	6.822	Down-regulation
Atypical_PIKK_FRAP_MTOR_ST	Q13541	EIF4EBP1	P42345	MTOR	T70	P72S	72	Missense	proximal	2	no	9.629	9.134	EPSD;PhosphoSitePlus	COSMIC	6.822	Down-regulation
Atypical_PIKK_FRAP_MTOR_ST	Q13541	EIF4EBP1	P42345	MTOR	T70	R63W	63	Missense	distal	-7	no	9.629	10.089	EPSD;PhosphoSitePlus	COSMIC	6.822	Up-regulation
Atypical_PIKK_FRAP_MTOR_ST	Q13541	EIF4EBP1	P42345	MTOR	S83	S85F	85	Missense	proximal	2	no	14.242	12.508	EPSD	COSMIC	6.822	Down-regulation
Atypical_PIKK_FRAP_MTOR_ST	Q13541	EIF4EBP1	P42345	MTOR	S101	N100H	100	Missense	proximal	-1	no	15.851	15.911	EPSD	COSMIC	6.822	Up-regulation
Atypical_PIKK_FRAP_MTOR_ST	Q13541	EIF4EBP1	P42345	MTOR	S101	R106L	106	Missense	distal	5	no	15.851	16.345	EPSD	COSMIC	6.822	Up-regulation
Atypical_PIKK_FRAP_MTOR_ST	P00441	SOD1	P42345	MTOR	S135	G142A	142	Missense	distal	7	no	9.177	8.367	EPSD	COSMIC	6.822	Down-regulation
Atypical_PIKK_FRAP_MTOR_ST	P00441	SOD1	P42345	MTOR	S135	G139E	139	Missense	distal	4	no	9.177	9.468	EPSD	COSMIC	6.822	Up-regulation
Atypical_PIKK_FRAP_MTOR_ST	P00441	SOD1	P42345	MTOR	T138	G139E	139	Missense	proximal	1	no	6.009	9.452	EPSD	COSMIC	6.822	Gain
Atypical_PIKK_FRAP_MTOR_ST	P00441	SOD1	P42345	MTOR	S143	G142A	142	Missense	proximal	-1	no	9.269	9.270	EPSD	COSMIC	6.822	Up-regulation
Atypical_PIKK_FRAP_MTOR_ST	P00441	SOD1	P42345	MTOR	S143	G139E	139	Missense	distal	-4	no	9.269	9.715	EPSD	COSMIC	6.822	Up-regulation
Atypical_PIKK_FRAP_MTOR_ST	P00441	SOD1	P42345	MTOR	S143	G148D	148	Missense	distal	5	no	9.269	8.642	EPSD	COSMIC	6.822	Down-regulation
Atypical_PIKK_FRAP_MTOR_ST	P00441	SOD1	P42345	MTOR	S143	V149A	149	Missense	distal	6	no	9.269	8.577	EPSD	COSMIC	6.822	Down-regulation
Atypical_PIKK_FRAP_MTOR_ST	O75179	ANKRD17	P42345	MTOR	S113	N115S	115	Missense	proximal	2	no	6.776	8.178	EPSD	COSMIC	6.822	Gain
Atypical_PIKK_FRAP_MTOR_ST	O75179	ANKRD17	P42345	MTOR	T735	L734V	734	Missense	proximal	-1	no	9.022	9.145	EPSD	COSMIC	6.822	Up-regulation
Atypical_PIKK_FRAP_MTOR_ST	O75179	ANKRD17	P42345	MTOR	S803	Y798H	798	Missense	distal	-5	no	7.586	7.239	EPSD	COSMIC;GDSC;CCLE	6.822	Down-regulation
Atypical_PIKK_FRAP_MTOR_ST	O75179	ANKRD17	P42345	MTOR	S803	Q802E	802	Missense	proximal	-1	no	7.586	7.697	EPSD	COSMIC	6.822	Up-regulation
Atypical_PIKK_FRAP_MTOR_ST	O75179	ANKRD17	P42345	MTOR	T913	L912P	912	Missense	proximal	-1	no	10.254	10.387	EPSD	COSMIC;GDSC	6.822	Up-regulation
Atypical_PIKK_FRAP_MTOR_ST	O75179	ANKRD17	P42345	MTOR	T913	C906Y	906	Missense	distal	-7	no	10.254	12.019	EPSD	COSMIC	6.822	Up-regulation
Atypical_PIKK_FRAP_MTOR_ST	O75179	ANKRD17	P42345	MTOR	T913	Q920H	920	Missense	distal	7	no	10.254	10.496	EPSD	COSMIC;CCLE	6.822	Up-regulation
Atypical_PIKK_FRAP_MTOR_ST	O75179	ANKRD17	P42345	MTOR	T913	Q920K	920	Missense	distal	7	no	10.254	9.507	EPSD	COSMIC	6.822	Down-regulation
Atypical_PIKK_FRAP_MTOR_ST	O75179	ANKRD17	P42345	MTOR	S1220	M1227V	1227	Missense	distal	7	no	10.849	11.222	EPSD	COSMIC	6.822	Up-regulation
Atypical_PIKK_FRAP_MTOR_ST	O75179	ANKRD17	P42345	MTOR	S1220	G1218C	1218	Missense	proximal	-2	no	10.849	10.269	EPSD	COSMIC	6.822	Down-regulation
Atypical_PIKK_FRAP_MTOR_ST	O75179	ANKRD17	P42345	MTOR	S1220	A1225T	1225	Missense	distal	5	no	10.849	10.024	EPSD	COSMIC	6.822	Down-regulation
Atypical_PIKK_FRAP_MTOR_ST	O75179	ANKRD17	P42345	MTOR	S1319	R1320T	1320	Missense	proximal	1	no	6.584	10.145	EPSD	COSMIC	6.822	Gain
Atypical_PIKK_FRAP_MTOR_ST	O75179	ANKRD17	P42345	MTOR	S1566	R1572S	1572	Missense	distal	6	no	5.046	6.868	EPSD	COSMIC	6.822	Gain
Atypical_PIKK_FRAP_MTOR_ST	O75179	ANKRD17	P42345	MTOR	S1607	S1605C	1605	Missense	proximal	-2	no	7.673	7.823	EPSD	COSMIC	6.822	Up-regulation
Atypical_PIKK_FRAP_MTOR_ST	O75179	ANKRD17	P42345	MTOR	S1607	G1612R	1612	Missense	distal	5	no	7.673	8.003	EPSD	COSMIC	6.822	Up-regulation
Atypical_PIKK_FRAP_MTOR_ST	O75179	ANKRD17	P42345	MTOR	S1654	V1657A	1657	Missense	distal	3	no	6.096	8.107	EPSD	COSMIC	6.822	Gain
Atypical_PIKK_FRAP_MTOR_ST	O75179	ANKRD17	P42345	MTOR	S1672	E1677K	1677	Missense	distal	5	no	7.344	7.398	EPSD	COSMIC	6.822	Up-regulation
Atypical_PIKK_FRAP_MTOR_ST	O75179	ANKRD17	P42345	MTOR	S1672	G1669V	1669	Missense	distal	-3	no	7.344	7.108	EPSD	COSMIC	6.822	Down-regulation
Atypical_PIKK_FRAP_MTOR_ST	O75179	ANKRD17	P42345	MTOR	S1672	S1676P	1676	Missense	distal	4	no	7.344	7.088	EPSD	COSMIC	6.822	Down-regulation
Atypical_PIKK_FRAP_MTOR_ST	O75179	ANKRD17	P42345	MTOR	S1696	S1699C	1699	Missense	distal	3	no	9.119	6.352	EPSD	COSMIC	6.822	Loss
Atypical_PIKK_FRAP_MTOR_ST	O75179	ANKRD17	P42345	MTOR	S1696	P1701L	1701	Missense	distal	5	no	9.119	10.492	EPSD	COSMIC	6.822	Up-regulation
Atypical_PIKK_FRAP_MTOR_ST	O75179	ANKRD17	P42345	MTOR	S1696	P1701S	1701	Missense	distal	5	no	9.119	9.005	EPSD	COSMIC;CCLE	6.822	Down-regulation
Atypical_PIKK_FRAP_MTOR_ST	O75179	ANKRD17	P42345	MTOR	S1700	S1699C	1699	Missense	proximal	-1	no	11.663	11.674	EPSD	COSMIC	6.822	Up-regulation
Atypical_PIKK_FRAP_MTOR_ST	O75179	ANKRD17	P42345	MTOR	S1700	V1707I	1707	Missense	distal	7	no	11.663	11.525	EPSD	COSMIC	6.822	Down-regulation
Atypical_PIKK_FRAP_MTOR_ST	O75179	ANKRD17	P42345	MTOR	S1700	T1706R	1706	Missense	distal	6	no	11.663	10.755	EPSD	COSMIC;GDSC;CCLE	6.822	Down-regulation
Atypical_PIKK_FRAP_MTOR_ST	O75179	ANKRD17	P42345	MTOR	S1700	P1701L	1701	Missense	proximal	1	no	11.663	5.694	EPSD	COSMIC	6.822	Loss
Atypical_PIKK_FRAP_MTOR_ST	O75179	ANKRD17	P42345	MTOR	S1700	P1701S	1701	Missense	proximal	1	no	11.663	3.139	EPSD	COSMIC;CCLE	6.822	Loss
Atypical_PIKK_FRAP_MTOR_ST	O75179	ANKRD17	P42345	MTOR	S1709	R1712L	1712	Missense	distal	3	no	12.485	10.496	EPSD	COSMIC	6.822	Down-regulation
Atypical_PIKK_FRAP_MTOR_ST	O75179	ANKRD17	P42345	MTOR	S1709	V1707I	1707	Missense	proximal	-2	no	12.485	11.963	EPSD	COSMIC	6.822	Down-regulation
Atypical_PIKK_FRAP_MTOR_ST	O75179	ANKRD17	P42345	MTOR	S1709	T1706R	1706	Missense	distal	-3	no	12.485	13.270	EPSD	COSMIC;GDSC;CCLE	6.822	Up-regulation
Atypical_PIKK_FRAP_MTOR_ST	O75179	ANKRD17	P42345	MTOR	S1731	V1732A	1732	Missense	proximal	1	no	6.898	4.736	EPSD	COSMIC	6.822	Loss
Atypical_PIKK_FRAP_MTOR_ST	O75179	ANKRD17	P42345	MTOR	S1731	V1730A	1730	Missense	proximal	-1	no	6.898	6.970	EPSD	COSMIC	6.822	Up-regulation
Atypical_PIKK_FRAP_MTOR_ST	O75179	ANKRD17	P42345	MTOR	S1731	S1738F	1738	Missense	distal	7	no	6.898	7.478	EPSD	COSMIC	6.822	Up-regulation
Atypical_PIKK_FRAP_MTOR_ST	O75179	ANKRD17	P42345	MTOR	S1731	I1737T	1737	Missense	distal	6	no	6.898	6.848	EPSD	COSMIC	6.822	Down-regulation
Atypical_PIKK_FRAP_MTOR_ST	O75179	ANKRD17	P42345	MTOR	S1731	S1727L	1727	Missense	distal	-4	no	6.898	6.583	EPSD	COSMIC	6.822	Loss
Atypical_PIKK_FRAP_MTOR_ST	O75179	ANKRD17	P42345	MTOR	S1734	V1732A	1732	Missense	proximal	-2	no	8.990	9.469	EPSD	COSMIC	6.822	Up-regulation
Atypical_PIKK_FRAP_MTOR_ST	O75179	ANKRD17	P42345	MTOR	S1734	V1730A	1730	Missense	distal	-4	no	8.990	8.710	EPSD	COSMIC	6.822	Down-regulation
Atypical_PIKK_FRAP_MTOR_ST	O75179	ANKRD17	P42345	MTOR	S1734	S1738F	1738	Missense	distal	4	no	8.990	8.746	EPSD	COSMIC	6.822	Down-regulation
Atypical_PIKK_FRAP_MTOR_ST	O75179	ANKRD17	P42345	MTOR	S1734	I1737T	1737	Missense	distal	3	no	8.990	10.795	EPSD	COSMIC	6.822	Up-regulation
Atypical_PIKK_FRAP_MTOR_ST	O75179	ANKRD17	P42345	MTOR	S1734	S1727L	1727	Missense	distal	-7	no	8.990	8.420	EPSD	COSMIC	6.822	Down-regulation
Atypical_PIKK_FRAP_MTOR_ST	O75179	ANKRD17	P42345	MTOR	S2045	Y2038F	2038	Missense	distal	-7	no	13.269	13.133	EPSD;PhosphoSitePlus	COSMIC	6.822	Down-regulation
Atypical_PIKK_FRAP_MTOR_ST	O75179	ANKRD17	P42345	MTOR	S2045	S2041L	2041	Missense	distal	-4	no	13.269	12.954	EPSD;PhosphoSitePlus	COSMIC	6.822	Down-regulation
Atypical_PIKK_FRAP_MTOR_ST	O75179	ANKRD17	P42345	MTOR	S2045	P2049Q	2049	Missense	distal	4	no	13.269	13.084	EPSD;PhosphoSitePlus	COSMIC	6.822	Down-regulation
Atypical_PIKK_FRAP_MTOR_ST	O75179	ANKRD17	P42345	MTOR	S2047	S2041L	2041	Missense	distal	-6	no	12.818	12.064	PhosphoSitePlus;EPSD	COSMIC	6.822	Down-regulation
Atypical_PIKK_FRAP_MTOR_ST	O75179	ANKRD17	P42345	MTOR	S2047	P2049Q	2049	Missense	proximal	2	no	12.818	10.599	PhosphoSitePlus;EPSD	COSMIC	6.822	Down-regulation
Atypical_PIKK_FRAP_MTOR_ST	O75179	ANKRD17	P42345	MTOR	S2059	D2062Y	2062	Missense	distal	3	no	12.200	11.734	EPSD	COSMIC	6.822	Down-regulation
Atypical_PIKK_FRAP_MTOR_ST	O75179	ANKRD17	P42345	MTOR	S2059	S2059I	2059	Missense	central	0	yes	12.200	0.000	EPSD	COSMIC;GDSC;CCLE	6.822	Loss
Atypical_PIKK_FRAP_MTOR_ST	O75179	ANKRD17	P42345	MTOR	S2081	V2084L	2084	Missense	distal	3	no	8.988	7.675	EPSD	COSMIC	6.822	Down-regulation
Atypical_PIKK_FRAP_MTOR_ST	O75179	ANKRD17	P42345	MTOR	S2081	S2075C	2075	Missense	distal	-6	no	8.988	9.222	EPSD	COSMIC	6.822	Up-regulation
Atypical_PIKK_FRAP_MTOR_ST	O75179	ANKRD17	P42345	MTOR	S2081	T2087A	2087	Missense	distal	6	no	8.988	9.251	EPSD	COSMIC	6.822	Up-regulation
Atypical_PIKK_FRAP_MTOR_ST	O75179	ANKRD17	P42345	MTOR	T2279	Q2277H	2277	Missense	proximal	-2	no	12.302	11.732	EPSD	COSMIC	6.822	Down-regulation
Atypical_PIKK_FRAP_MTOR_ST	O75179	ANKRD17	P42345	MTOR	T2279	S2272P	2272	Missense	distal	-7	no	12.302	11.865	EPSD	COSMIC;GDSC;CCLE	6.822	Down-regulation
Atypical_PIKK_FRAP_MTOR_ST	O75179	ANKRD17	P42345	MTOR	T2279	G2286W	2286	Missense	distal	7	no	12.302	12.324	EPSD	COSMIC	6.822	Up-regulation
Atypical_PIKK_FRAP_MTOR_ST	O75179	ANKRD17	P42345	MTOR	S2289	S2294L	2294	Missense	distal	5	no	7.521	9.008	EPSD	COSMIC	6.822	Up-regulation
Atypical_PIKK_FRAP_MTOR_ST	O75179	ANKRD17	P42345	MTOR	S2289	P2296S	2296	Missense	distal	7	no	7.521	7.500	EPSD	COSMIC	6.822	Down-regulation
Atypical_PIKK_FRAP_MTOR_ST	O75179	ANKRD17	P42345	MTOR	S2289	G2286W	2286	Missense	distal	-3	no	7.521	7.280	EPSD	COSMIC	6.822	Down-regulation
Atypical_PIKK_FRAP_MTOR_ST	O75179	ANKRD17	P42345	MTOR	S2373	P2374L	2374	Missense	proximal	1	no	11.026	5.057	EPSD	COSMIC	6.822	Loss
Atypical_PIKK_FRAP_MTOR_ST	O75179	ANKRD17	P42345	MTOR	S2373	P2374Q	2374	Missense	proximal	1	no	11.026	2.412	EPSD	COSMIC	6.822	Loss
Atypical_PIKK_FRAP_MTOR_ST	O75179	ANKRD17	P42345	MTOR	S2373	P2380S	2380	Missense	distal	7	no	11.026	11.005	EPSD	COSMIC	6.822	Down-regulation
Atypical_PIKK_FRAP_MTOR_ST	O75179	ANKRD17	P42345	MTOR	S2401	R2398H	2398	Missense	distal	-3	no	11.495	10.748	EPSD	COSMIC	6.822	Down-regulation
Atypical_PIKK_FRAP_MTOR_ST	O75179	ANKRD17	P42345	MTOR	S2401	P2408Q	2408	Missense	distal	7	no	11.495	11.867	EPSD	COSMIC	6.822	Up-regulation
Atypical_PIKK_FRAP_MTOR_ST	O75179	ANKRD17	P42345	MTOR	S2401	P2402S	2402	Missense	proximal	1	no	11.495	2.971	EPSD	COSMIC	6.822	Loss
Atypical_PIKK_FRAP_MTOR_ST	O75179	ANKRD17	P42345	MTOR	T2438	G2439V	2439	Missense	proximal	1	no	3.964	8.869	EPSD	COSMIC;GDSC;CCLE	6.822	Gain
Atypical_PIKK_FRAP_MTOR_ST	O75179	ANKRD17	P42345	MTOR	S2448	S2444Y	2444	Missense	distal	-4	no	10.470	9.840	EPSD	COSMIC	6.822	Down-regulation
Atypical_PIKK_FRAP_MTOR_ST	O75179	ANKRD17	P42345	MTOR	T2509	S2511F	2511	Missense	proximal	2	no	9.021	7.287	EPSD	COSMIC	6.822	Down-regulation
Atypical_PIKK_FRAP_MTOR_ST	O75179	ANKRD17	P42345	MTOR	T2509	G2512A	2512	Missense	distal	3	no	9.021	9.008	EPSD	COSMIC;GDSC	6.822	Down-regulation
Atypical_PIKK_FRAP_MTOR_ST	O75179	ANKRD17	P42345	MTOR	T2509	P2510L	2510	Missense	proximal	1	no	9.021	3.052	EPSD	COSMIC	6.822	Loss
Atypical_PIKK_FRAP_MTOR_ST	O75179	ANKRD17	P42345	MTOR	T2509	G2506A	2506	Missense	distal	-3	no	9.021	8.156	EPSD	COSMIC;GDSC;CCLE	6.822	Down-regulation
Atypical_PIKK_FRAP_MTOR_ST	Q9HB90	RRAGC	P42345	MTOR	S86	P87H	87	Missense	proximal	1	no	9.375	-17.816	EPSD	COSMIC	6.822	Loss
Atypical_PIKK_FRAP_MTOR_ST	Q9HB90	RRAGC	P42345	MTOR	S86	H83Y	83	Missense	distal	-3	no	9.375	10.015	EPSD	COSMIC	6.822	Up-regulation
Atypical_PIKK_FRAP_MTOR_ST	Q9HB90	RRAGC	P42345	MTOR	S382	S384C	384	Missense	proximal	2	no	7.160	5.614	EPSD	COSMIC	6.822	Loss
Atypical_PIKK_FRAP_MTOR_ST	Q9HB90	RRAGC	P42345	MTOR	T394	T394M	394	Missense	central	0	yes	8.997	0.000	EPSD;PhosphoSitePlus	COSMIC	6.822	Loss
Atypical_PIKK_FRAP_MTOR_ST	Q9HB90	RRAGC	P42345	MTOR	T394	A398T	398	Missense	distal	4	no	8.997	9.539	EPSD;PhosphoSitePlus	COSMIC	6.822	Up-regulation
Atypical_PIKK_FRAP_MTOR_ST	O00418	EEF2K	P42345	MTOR	S18	G22R	22	Missense	distal	4	no	13.463	13.413	EPSD	COSMIC	6.822	Down-regulation
Atypical_PIKK_FRAP_MTOR_ST	O00418	EEF2K	P42345	MTOR	S18	V13I	13	Missense	distal	-5	no	13.463	13.590	EPSD	COSMIC	6.822	Up-regulation
Atypical_PIKK_FRAP_MTOR_ST	O00418	EEF2K	P42345	MTOR	S359	T364N	364	Missense	distal	5	no	6.318	8.196	EPSD	COSMIC	6.822	Gain
Atypical_PIKK_FRAP_MTOR_ST	O00418	EEF2K	P42345	MTOR	T389	V388M	388	Missense	proximal	-1	no	7.817	7.792	EPSD	COSMIC;CCLE	6.822	Down-regulation
Atypical_PIKK_FRAP_MTOR_ST	O00418	EEF2K	P42345	MTOR	T389	E383D	383	Missense	distal	-6	no	7.817	8.006	EPSD	COSMIC	6.822	Up-regulation
Atypical_PIKK_FRAP_MTOR_ST	O00418	EEF2K	P42345	MTOR	T389	T389I	389	Missense	central	0	yes	7.817	0.000	EPSD	COSMIC	6.822	Loss
Atypical_PIKK_FRAP_MTOR_ST	O00418	EEF2K	P42345	MTOR	T389	P394L	394	Missense	distal	5	no	7.817	9.190	EPSD	COSMIC;GDSC;CCLE	6.822	Up-regulation
Atypical_PIKK_FRAP_MTOR_ST	O00418	EEF2K	P42345	MTOR	T389	P394S	394	Missense	distal	5	no	7.817	7.703	EPSD	COSMIC	6.822	Down-regulation
Atypical_PIKK_FRAP_MTOR_ST	O00418	EEF2K	P42345	MTOR	S396	S398C	398	Missense	proximal	2	no	7.533	5.987	EPSD	COSMIC	6.822	Loss
Atypical_PIKK_FRAP_MTOR_ST	O00418	EEF2K	P42345	MTOR	S396	T389I	389	Missense	distal	-7	no	7.533	6.476	EPSD	COSMIC	6.822	Loss
Atypical_PIKK_FRAP_MTOR_ST	O00418	EEF2K	P42345	MTOR	S396	S399L	399	Missense	distal	3	no	7.533	5.265	EPSD	COSMIC	6.822	Loss
Atypical_PIKK_FRAP_MTOR_ST	O00418	EEF2K	P42345	MTOR	S396	P394L	394	Missense	proximal	-2	no	7.533	7.043	EPSD	COSMIC;GDSC;CCLE	6.822	Down-regulation
Atypical_PIKK_FRAP_MTOR_ST	O00418	EEF2K	P42345	MTOR	S396	P394S	394	Missense	proximal	-2	no	7.533	7.177	EPSD	COSMIC	6.822	Down-regulation
Atypical_PIKK_FRAP_MTOR_ST	O00418	EEF2K	P42345	MTOR	S398	S399L	399	Missense	proximal	1	no	5.974	8.529	EPSD	COSMIC	6.822	Gain
Atypical_PIKK_FRAP_MTOR_ST	O00418	EEF2K	P42345	MTOR	S627	S622Y	622	Missense	distal	-5	no	10.759	11.252	EPSD	COSMIC	6.822	Up-regulation
Atypical_PIKK_FRAP_MTOR_ST	O00418	EEF2K	P42345	MTOR	S627	C631R	631	Missense	distal	4	no	10.759	10.972	EPSD	COSMIC	6.822	Up-regulation
Atypical_PIKK_FRAP_MTOR_ST	O00418	EEF2K	P42345	MTOR	S627	Q624L	624	Missense	distal	-3	no	10.759	11.437	EPSD	COSMIC	6.822	Up-regulation
Atypical_PIKK_FRAP_MTOR_ST	Q9UQ35	SRRM2	P42345	MTOR	T111	G113R	113	Missense	proximal	2	no	7.502	5.969	EPSD	COSMIC	6.822	Loss
Atypical_PIKK_FRAP_MTOR_ST	Q9UQ35	SRRM2	P42345	MTOR	S172	R175Q	175	Missense	distal	3	no	8.383	7.117	EPSD	COSMIC	6.822	Down-regulation
Atypical_PIKK_FRAP_MTOR_ST	Q9UQ35	SRRM2	P42345	MTOR	S182	P185Q	185	Missense	distal	3	no	11.510	9.978	EPSD	COSMIC	6.822	Down-regulation
Atypical_PIKK_FRAP_MTOR_ST	Q9UQ35	SRRM2	P42345	MTOR	S182	R175Q	175	Missense	distal	-7	no	11.510	11.432	EPSD	COSMIC	6.822	Down-regulation
Atypical_PIKK_FRAP_MTOR_ST	Q9UQ35	SRRM2	P42345	MTOR	T184	P185Q	185	Missense	proximal	1	no	11.408	2.794	EPSD	COSMIC	6.822	Loss
Atypical_PIKK_FRAP_MTOR_ST	Q9UQ35	SRRM2	P42345	MTOR	S204	R207H	207	Missense	distal	3	no	8.276	8.446	EPSD	COSMIC	6.822	Up-regulation
Atypical_PIKK_FRAP_MTOR_ST	Q9UQ35	SRRM2	P42345	MTOR	S204	S202C	202	Missense	proximal	-2	no	8.276	8.426	EPSD	COSMIC	6.822	Up-regulation
Atypical_PIKK_FRAP_MTOR_ST	Q9UQ35	SRRM2	P42345	MTOR	S204	R198H	198	Missense	distal	-6	no	8.276	7.470	EPSD	COSMIC	6.822	Down-regulation
Atypical_PIKK_FRAP_MTOR_ST	Q9UQ35	SRRM2	P42345	MTOR	S231	H229Y	229	Missense	proximal	-2	no	9.139	8.955	EPSD	COSMIC	6.822	Down-regulation
Atypical_PIKK_FRAP_MTOR_ST	Q9UQ35	SRRM2	P42345	MTOR	S271	S277T	277	Missense	distal	6	no	7.939	7.025	EPSD	COSMIC	6.822	Down-regulation
Atypical_PIKK_FRAP_MTOR_ST	Q9UQ35	SRRM2	P42345	MTOR	S271	R278Q	278	Missense	distal	7	no	7.939	7.540	EPSD	COSMIC	6.822	Down-regulation
Atypical_PIKK_FRAP_MTOR_ST	Q9UQ35	SRRM2	P42345	MTOR	S295	A290S	290	Missense	distal	-5	no	11.978	11.951	EPSD	COSMIC	6.822	Down-regulation
Atypical_PIKK_FRAP_MTOR_ST	Q9UQ35	SRRM2	P42345	MTOR	S297	A290S	290	Missense	distal	-7	no	9.264	10.105	EPSD	COSMIC	6.822	Up-regulation
Atypical_PIKK_FRAP_MTOR_ST	Q9UQ35	SRRM2	P42345	MTOR	S323	K329R	329	Missense	distal	6	no	15.265	14.178	EPSD	COSMIC	6.822	Down-regulation
Atypical_PIKK_FRAP_MTOR_ST	Q9UQ35	SRRM2	P42345	MTOR	S323	T326I	326	Missense	distal	3	no	15.265	13.460	EPSD	COSMIC	6.822	Down-regulation
Atypical_PIKK_FRAP_MTOR_ST	Q9UQ35	SRRM2	P42345	MTOR	S323	R320W	320	Missense	distal	-3	no	15.265	15.049	EPSD	COSMIC	6.822	Down-regulation
Atypical_PIKK_FRAP_MTOR_ST	Q9UQ35	SRRM2	P42345	MTOR	S323	E325Q	325	Missense	proximal	2	no	15.265	12.702	EPSD	COSMIC	6.822	Down-regulation
Atypical_PIKK_FRAP_MTOR_ST	Q9UQ35	SRRM2	P42345	MTOR	S333	K329R	329	Missense	distal	-4	no	6.505	7.039	EPSD	COSMIC	6.822	Gain
Atypical_PIKK_FRAP_MTOR_ST	Q9UQ35	SRRM2	P42345	MTOR	S351	S351N	351	Missense	central	0	yes	12.023	0.000	EPSD	COSMIC	6.822	Loss
Atypical_PIKK_FRAP_MTOR_ST	Q9UQ35	SRRM2	P42345	MTOR	S353	G360D	360	Missense	distal	7	no	10.140	10.317	EPSD	COSMIC	6.822	Up-regulation
Atypical_PIKK_FRAP_MTOR_ST	Q9UQ35	SRRM2	P42345	MTOR	S353	S351N	351	Missense	proximal	-2	no	10.140	9.549	EPSD	COSMIC	6.822	Down-regulation
Atypical_PIKK_FRAP_MTOR_ST	Q9UQ35	SRRM2	P42345	MTOR	T367	G360D	360	Missense	distal	-7	no	9.152	9.959	EPSD	COSMIC	6.822	Up-regulation
Atypical_PIKK_FRAP_MTOR_ST	Q9UQ35	SRRM2	P42345	MTOR	S398	D402G	402	Missense	distal	4	no	8.860	8.408	EPSD	COSMIC	6.822	Down-regulation
Atypical_PIKK_FRAP_MTOR_ST	Q9UQ35	SRRM2	P42345	MTOR	S398	R403C	403	Missense	distal	5	no	8.860	8.644	EPSD	COSMIC;GDSC;CCLE	6.822	Down-regulation
Atypical_PIKK_FRAP_MTOR_ST	Q9UQ35	SRRM2	P42345	MTOR	S398	R403H	403	Missense	distal	5	no	8.860	9.165	EPSD	COSMIC;GDSC;CCLE	6.822	Up-regulation
Atypical_PIKK_FRAP_MTOR_ST	Q9UQ35	SRRM2	P42345	MTOR	S398	P394T	394	Missense	distal	-4	no	8.860	8.487	EPSD	COSMIC	6.822	Down-regulation
Atypical_PIKK_FRAP_MTOR_ST	Q9UQ35	SRRM2	P42345	MTOR	S398	T400I	400	Missense	proximal	2	no	8.860	8.871	EPSD	COSMIC;GDSC;CCLE	6.822	Up-regulation
Atypical_PIKK_FRAP_MTOR_ST	Q9UQ35	SRRM2	P42345	MTOR	S404	D402G	402	Missense	proximal	-2	no	6.389	7.443	EPSD	COSMIC	6.822	Gain
Atypical_PIKK_FRAP_MTOR_ST	Q9UQ35	SRRM2	P42345	MTOR	S420	S421I	421	Missense	proximal	1	no	3.654	7.119	EPSD	COSMIC;GDSC;CCLE	6.822	Gain
Atypical_PIKK_FRAP_MTOR_ST	Q9UQ35	SRRM2	P42345	MTOR	S421	S421I	421	Missense	central	0	yes	7.951	0.000	EPSD	COSMIC;GDSC;CCLE	6.822	Loss
Atypical_PIKK_FRAP_MTOR_ST	Q9UQ35	SRRM2	P42345	MTOR	S421	S417F	417	Missense	distal	-4	no	7.951	7.976	EPSD	COSMIC	6.822	Up-regulation
Atypical_PIKK_FRAP_MTOR_ST	Q9UQ35	SRRM2	P42345	MTOR	S421	S415P	415	Missense	distal	-6	no	7.951	7.972	EPSD	COSMIC	6.822	Up-regulation
Atypical_PIKK_FRAP_MTOR_ST	Q9UQ35	SRRM2	P42345	MTOR	S421	P427T	427	Missense	distal	6	no	7.951	7.067	EPSD	COSMIC	6.822	Down-regulation
Atypical_PIKK_FRAP_MTOR_ST	Q9UQ35	SRRM2	P42345	MTOR	S424	S421I	421	Missense	distal	-3	no	9.024	9.459	EPSD	COSMIC;GDSC;CCLE	6.822	Up-regulation
Atypical_PIKK_FRAP_MTOR_ST	Q9UQ35	SRRM2	P42345	MTOR	S424	S417F	417	Missense	distal	-7	no	9.024	8.799	EPSD	COSMIC	6.822	Down-regulation
Atypical_PIKK_FRAP_MTOR_ST	Q9UQ35	SRRM2	P42345	MTOR	S424	P427T	427	Missense	distal	3	no	9.024	8.631	EPSD	COSMIC	6.822	Down-regulation
Atypical_PIKK_FRAP_MTOR_ST	Q9UQ35	SRRM2	P42345	MTOR	S437	R432W	432	Missense	distal	-5	no	9.383	9.441	EPSD	COSMIC;GDSC	6.822	Up-regulation
Atypical_PIKK_FRAP_MTOR_ST	Q9UQ35	SRRM2	P42345	MTOR	S440	P445L	445	Missense	distal	5	no	6.724	8.097	EPSD	COSMIC	6.822	Gain
Atypical_PIKK_FRAP_MTOR_ST	Q9UQ35	SRRM2	P42345	MTOR	S456	H450Y	450	Missense	distal	-6	no	11.934	11.763	EPSD	COSMIC	6.822	Down-regulation
Atypical_PIKK_FRAP_MTOR_ST	Q9UQ35	SRRM2	P42345	MTOR	S456	S455F	455	Missense	proximal	-1	no	11.934	11.750	EPSD	COSMIC	6.822	Down-regulation
Atypical_PIKK_FRAP_MTOR_ST	Q9UQ35	SRRM2	P42345	MTOR	T476	R479C	479	Missense	distal	3	no	8.522	6.034	EPSD	COSMIC	6.822	Loss
Atypical_PIKK_FRAP_MTOR_ST	Q9UQ35	SRRM2	P42345	MTOR	T476	R479H	479	Missense	distal	3	no	8.522	8.691	EPSD	COSMIC	6.822	Up-regulation
Atypical_PIKK_FRAP_MTOR_ST	Q9UQ35	SRRM2	P42345	MTOR	T476	P477L	477	Missense	proximal	1	no	8.522	2.552	EPSD	COSMIC	6.822	Loss
Atypical_PIKK_FRAP_MTOR_ST	Q9UQ35	SRRM2	P42345	MTOR	S486	A490T	490	Missense	distal	4	no	9.657	10.199	EPSD	COSMIC;GDSC	6.822	Up-regulation
Atypical_PIKK_FRAP_MTOR_ST	Q9UQ35	SRRM2	P42345	MTOR	S486	R479C	479	Missense	distal	-7	no	9.657	8.562	EPSD	COSMIC	6.822	Down-regulation
Atypical_PIKK_FRAP_MTOR_ST	Q9UQ35	SRRM2	P42345	MTOR	S486	R479H	479	Missense	distal	-7	no	9.657	9.308	EPSD	COSMIC	6.822	Down-regulation
Atypical_PIKK_FRAP_MTOR_ST	Q9UQ35	SRRM2	P42345	MTOR	S534	G541C	541	Missense	distal	7	no	7.694	8.533	EPSD	COSMIC	6.822	Up-regulation
Atypical_PIKK_FRAP_MTOR_ST	Q9UQ35	SRRM2	P42345	MTOR	S534	Q538R	538	Missense	distal	4	no	7.694	7.563	EPSD	COSMIC	6.822	Down-regulation
Atypical_PIKK_FRAP_MTOR_ST	Q9UQ35	SRRM2	P42345	MTOR	S536	G541C	541	Missense	distal	5	no	6.767	6.881	EPSD	COSMIC	6.822	Gain
Atypical_PIKK_FRAP_MTOR_ST	Q9UQ35	SRRM2	P42345	MTOR	S543	G541C	541	Missense	proximal	-2	no	6.935	6.355	EPSD	COSMIC	6.822	Loss
Atypical_PIKK_FRAP_MTOR_ST	Q9UQ35	SRRM2	P42345	MTOR	S543	Q538R	538	Missense	distal	-5	no	6.935	7.020	EPSD	COSMIC	6.822	Up-regulation
Atypical_PIKK_FRAP_MTOR_ST	Q9UQ35	SRRM2	P42345	MTOR	S566	R572I	572	Missense	distal	6	no	11.868	12.827	EPSD	COSMIC	6.822	Up-regulation
Atypical_PIKK_FRAP_MTOR_ST	Q9UQ35	SRRM2	P42345	MTOR	S566	S573Y	573	Missense	distal	7	no	11.868	11.470	EPSD	COSMIC	6.822	Down-regulation
Atypical_PIKK_FRAP_MTOR_ST	Q9UQ35	SRRM2	P42345	MTOR	T577	R574C	574	Missense	distal	-3	no	7.518	6.806	EPSD	COSMIC	6.822	Loss
Atypical_PIKK_FRAP_MTOR_ST	Q9UQ35	SRRM2	P42345	MTOR	T577	R572I	572	Missense	distal	-5	no	7.518	7.441	EPSD	COSMIC	6.822	Down-regulation
Atypical_PIKK_FRAP_MTOR_ST	Q9UQ35	SRRM2	P42345	MTOR	T577	R581W	581	Missense	distal	4	no	7.518	7.679	EPSD	COSMIC;GDSC;CCLE	6.822	Up-regulation
Atypical_PIKK_FRAP_MTOR_ST	Q9UQ35	SRRM2	P42345	MTOR	T577	S573Y	573	Missense	distal	-4	no	7.518	6.887	EPSD	COSMIC	6.822	Down-regulation
Atypical_PIKK_FRAP_MTOR_ST	Q9UQ35	SRRM2	P42345	MTOR	T577	R574H	574	Missense	distal	-3	no	7.518	6.771	EPSD	COSMIC	6.822	Loss
Atypical_PIKK_FRAP_MTOR_ST	Q9UQ35	SRRM2	P42345	MTOR	T577	G582S	582	Missense	distal	5	no	7.518	6.855	EPSD	COSMIC	6.822	Down-regulation
Atypical_PIKK_FRAP_MTOR_ST	Q9UQ35	SRRM2	P42345	MTOR	T588	R581W	581	Missense	distal	-7	no	8.675	9.136	EPSD	COSMIC;GDSC;CCLE	6.822	Up-regulation
Atypical_PIKK_FRAP_MTOR_ST	Q9UQ35	SRRM2	P42345	MTOR	T588	G582S	582	Missense	distal	-6	no	8.675	8.553	EPSD	COSMIC	6.822	Down-regulation
Atypical_PIKK_FRAP_MTOR_ST	Q9UQ35	SRRM2	P42345	MTOR	T588	R595L	595	Missense	distal	7	no	8.675	8.860	EPSD	COSMIC	6.822	Up-regulation
Atypical_PIKK_FRAP_MTOR_ST	Q9UQ35	SRRM2	P42345	MTOR	T598	P599S	599	Missense	proximal	1	no	11.114	2.590	EPSD	COSMIC	6.822	Loss
Atypical_PIKK_FRAP_MTOR_ST	Q9UQ35	SRRM2	P42345	MTOR	T598	R602H	602	Missense	distal	4	no	11.114	10.855	EPSD	COSMIC	6.822	Down-regulation
Atypical_PIKK_FRAP_MTOR_ST	Q9UQ35	SRRM2	P42345	MTOR	T598	R605Q	605	Missense	distal	7	no	11.114	10.714	EPSD	COSMIC	6.822	Down-regulation
Atypical_PIKK_FRAP_MTOR_ST	Q9UQ35	SRRM2	P42345	MTOR	T598	R595L	595	Missense	distal	-3	no	11.114	11.183	EPSD	COSMIC	6.822	Up-regulation
Atypical_PIKK_FRAP_MTOR_ST	Q9UQ35	SRRM2	P42345	MTOR	T608	G613S	613	Missense	distal	5	no	9.975	9.313	EPSD	COSMIC	6.822	Down-regulation
Atypical_PIKK_FRAP_MTOR_ST	Q9UQ35	SRRM2	P42345	MTOR	T608	R602H	602	Missense	distal	-6	no	9.975	9.169	EPSD	COSMIC	6.822	Down-regulation
Atypical_PIKK_FRAP_MTOR_ST	Q9UQ35	SRRM2	P42345	MTOR	T608	R605Q	605	Missense	distal	-3	no	9.975	9.367	EPSD	COSMIC	6.822	Down-regulation
Atypical_PIKK_FRAP_MTOR_ST	Q9UQ35	SRRM2	P42345	MTOR	T608	R611L	611	Missense	distal	3	no	9.975	7.986	EPSD	COSMIC	6.822	Down-regulation
Atypical_PIKK_FRAP_MTOR_ST	Q9UQ35	SRRM2	P42345	MTOR	T619	G613S	613	Missense	distal	-6	no	8.869	8.747	EPSD	COSMIC	6.822	Down-regulation
Atypical_PIKK_FRAP_MTOR_ST	Q9UQ35	SRRM2	P42345	MTOR	T619	R622K	622	Missense	distal	3	no	8.869	7.770	EPSD	COSMIC	6.822	Down-regulation
Atypical_PIKK_FRAP_MTOR_ST	Q9UQ35	SRRM2	P42345	MTOR	T619	R616W	616	Missense	distal	-3	no	8.869	8.653	EPSD	COSMIC;CCLE	6.822	Down-regulation
Atypical_PIKK_FRAP_MTOR_ST	Q9UQ35	SRRM2	P42345	MTOR	S629	R636H	636	Missense	distal	7	no	10.965	10.808	EPSD	COSMIC	6.822	Down-regulation
Atypical_PIKK_FRAP_MTOR_ST	Q9UQ35	SRRM2	P42345	MTOR	S629	R622K	622	Missense	distal	-7	no	10.965	11.111	EPSD	COSMIC	6.822	Up-regulation
Atypical_PIKK_FRAP_MTOR_ST	Q9UQ35	SRRM2	P42345	MTOR	S639	R636H	636	Missense	distal	-3	no	15.180	14.433	EPSD	COSMIC	6.822	Down-regulation
Atypical_PIKK_FRAP_MTOR_ST	Q9UQ35	SRRM2	P42345	MTOR	S639	R646S	646	Missense	distal	7	no	15.180	14.387	EPSD	COSMIC	6.822	Down-regulation
Atypical_PIKK_FRAP_MTOR_ST	Q9UQ35	SRRM2	P42345	MTOR	T651	R657L	657	Missense	distal	6	no	6.496	7.129	EPSD	COSMIC	6.822	Gain
Atypical_PIKK_FRAP_MTOR_ST	Q9UQ35	SRRM2	P42345	MTOR	T662	R655C	655	Missense	distal	-7	no	7.283	6.188	EPSD	COSMIC;GDSC;CCLE	6.822	Loss
Atypical_PIKK_FRAP_MTOR_ST	Q9UQ35	SRRM2	P42345	MTOR	T662	R666H	666	Missense	distal	4	no	7.283	7.023	EPSD	COSMIC	6.822	Down-regulation
Atypical_PIKK_FRAP_MTOR_ST	Q9UQ35	SRRM2	P42345	MTOR	T662	A664T	664	Missense	proximal	2	no	7.283	7.987	EPSD	COSMIC	6.822	Up-regulation
Atypical_PIKK_FRAP_MTOR_ST	Q9UQ35	SRRM2	P42345	MTOR	T662	R657H	657	Missense	distal	-5	no	7.283	7.287	EPSD	COSMIC	6.822	Up-regulation
Atypical_PIKK_FRAP_MTOR_ST	Q9UQ35	SRRM2	P42345	MTOR	T662	R655H	655	Missense	distal	-7	no	7.283	6.934	EPSD	COSMIC	6.822	Down-regulation
Atypical_PIKK_FRAP_MTOR_ST	Q9UQ35	SRRM2	P42345	MTOR	T662	R657L	657	Missense	distal	-5	no	7.283	7.118	EPSD	COSMIC	6.822	Down-regulation
Atypical_PIKK_FRAP_MTOR_ST	Q9UQ35	SRRM2	P42345	MTOR	S727	R730Q	730	Missense	distal	3	no	10.594	9.327	EPSD	COSMIC	6.822	Down-regulation
Atypical_PIKK_FRAP_MTOR_ST	Q9UQ35	SRRM2	P42345	MTOR	S727	S726L	726	Missense	proximal	-1	no	10.594	10.392	EPSD	COSMIC	6.822	Down-regulation
Atypical_PIKK_FRAP_MTOR_ST	Q9UQ35	SRRM2	P42345	MTOR	S727	S724F	724	Missense	distal	-3	no	10.594	10.665	EPSD	COSMIC	6.822	Up-regulation
Atypical_PIKK_FRAP_MTOR_ST	Q9UQ35	SRRM2	P42345	MTOR	S746	S741G	741	Missense	distal	-5	no	6.755	6.822	EPSD	COSMIC	6.822	Gain
Atypical_PIKK_FRAP_MTOR_ST	Q9UQ35	SRRM2	P42345	MTOR	S761	S755F	755	Missense	distal	-6	no	9.676	9.201	EPSD	COSMIC	6.822	Down-regulation
Atypical_PIKK_FRAP_MTOR_ST	Q9UQ35	SRRM2	P42345	MTOR	S761	S764L	764	Missense	distal	3	no	9.676	7.408	EPSD	COSMIC	6.822	Down-regulation
Atypical_PIKK_FRAP_MTOR_ST	Q9UQ35	SRRM2	P42345	MTOR	S764	S764L	764	Missense	central	0	yes	10.278	0.000	EPSD	COSMIC	6.822	Loss
Atypical_PIKK_FRAP_MTOR_ST	Q9UQ35	SRRM2	P42345	MTOR	S778	P784L	784	Missense	distal	6	no	7.398	6.238	EPSD	COSMIC	6.822	Loss
Atypical_PIKK_FRAP_MTOR_ST	Q9UQ35	SRRM2	P42345	MTOR	S783	Q788K	788	Missense	distal	5	no	10.880	10.366	EPSD	COSMIC	6.822	Down-regulation
Atypical_PIKK_FRAP_MTOR_ST	Q9UQ35	SRRM2	P42345	MTOR	S783	P784L	784	Missense	proximal	1	no	10.880	4.911	EPSD	COSMIC	6.822	Loss
Atypical_PIKK_FRAP_MTOR_ST	Q9UQ35	SRRM2	P42345	MTOR	T792	Q788K	788	Missense	distal	-4	no	8.079	8.042	EPSD	COSMIC	6.822	Down-regulation
Atypical_PIKK_FRAP_MTOR_ST	Q9UQ35	SRRM2	P42345	MTOR	T792	R796C	796	Missense	distal	4	no	8.079	7.866	EPSD	COSMIC	6.822	Down-regulation
Atypical_PIKK_FRAP_MTOR_ST	Q9UQ35	SRRM2	P42345	MTOR	T810	R816H	816	Missense	distal	6	no	6.549	6.865	EPSD	COSMIC	6.822	Gain
Atypical_PIKK_FRAP_MTOR_ST	Q9UQ35	SRRM2	P42345	MTOR	S820	R814C	814	Missense	distal	-6	no	11.057	11.184	EPSD	COSMIC	6.822	Up-regulation
Atypical_PIKK_FRAP_MTOR_ST	Q9UQ35	SRRM2	P42345	MTOR	S820	R816H	816	Missense	distal	-4	no	11.057	9.863	EPSD	COSMIC	6.822	Down-regulation
Atypical_PIKK_FRAP_MTOR_ST	Q9UQ35	SRRM2	P42345	MTOR	S820	R814H	814	Missense	distal	-6	no	11.057	10.250	EPSD	COSMIC;CCLE	6.822	Down-regulation
Atypical_PIKK_FRAP_MTOR_ST	Q9UQ35	SRRM2	P42345	MTOR	S854	T856R	856	Missense	proximal	2	no	8.160	6.506	EPSD	COSMIC	6.822	Loss
Atypical_PIKK_FRAP_MTOR_ST	Q9UQ35	SRRM2	P42345	MTOR	T866	S864F	864	Missense	proximal	-2	no	7.535	7.714	EPSD	COSMIC	6.822	Up-regulation
Atypical_PIKK_FRAP_MTOR_ST	Q9UQ35	SRRM2	P42345	MTOR	T885	T885I	885	Missense	central	0	yes	11.329	0.000	EPSD	COSMIC	6.822	Loss
Atypical_PIKK_FRAP_MTOR_ST	Q9UQ35	SRRM2	P42345	MTOR	T885	C891Y	891	Missense	distal	6	no	11.329	11.592	EPSD	COSMIC	6.822	Up-regulation
Atypical_PIKK_FRAP_MTOR_ST	Q9UQ35	SRRM2	P42345	MTOR	T885	S892L	892	Missense	distal	7	no	11.329	12.307	EPSD	COSMIC	6.822	Up-regulation
Atypical_PIKK_FRAP_MTOR_ST	Q9UQ35	SRRM2	P42345	MTOR	S895	S901C	901	Missense	distal	6	no	7.644	5.949	EPSD	COSMIC	6.822	Loss
Atypical_PIKK_FRAP_MTOR_ST	Q9UQ35	SRRM2	P42345	MTOR	S895	C891Y	891	Missense	distal	-4	no	7.644	8.839	EPSD	COSMIC	6.822	Up-regulation
Atypical_PIKK_FRAP_MTOR_ST	Q9UQ35	SRRM2	P42345	MTOR	S895	P897S	897	Missense	proximal	2	no	7.644	7.150	EPSD	COSMIC	6.822	Down-regulation
Atypical_PIKK_FRAP_MTOR_ST	Q9UQ35	SRRM2	P42345	MTOR	S895	S892L	892	Missense	distal	-3	no	7.644	8.059	EPSD	COSMIC	6.822	Up-regulation
Atypical_PIKK_FRAP_MTOR_ST	Q9UQ35	SRRM2	P42345	MTOR	T903	S901C	901	Missense	proximal	-2	no	9.614	9.764	EPSD	COSMIC	6.822	Up-regulation
Atypical_PIKK_FRAP_MTOR_ST	Q9UQ35	SRRM2	P42345	MTOR	T903	R906T	906	Missense	distal	3	no	9.614	9.487	EPSD	COSMIC	6.822	Down-regulation
Atypical_PIKK_FRAP_MTOR_ST	Q9UQ35	SRRM2	P42345	MTOR	T903	P897S	897	Missense	distal	-6	no	9.614	9.594	EPSD	COSMIC	6.822	Down-regulation
Atypical_PIKK_FRAP_MTOR_ST	Q9UQ35	SRRM2	P42345	MTOR	S908	S901C	901	Missense	distal	-7	no	8.321	6.467	EPSD	COSMIC	6.822	Loss
Atypical_PIKK_FRAP_MTOR_ST	Q9UQ35	SRRM2	P42345	MTOR	S908	R906T	906	Missense	proximal	-2	no	8.321	8.513	EPSD	COSMIC	6.822	Up-regulation
Atypical_PIKK_FRAP_MTOR_ST	Q9UQ35	SRRM2	P42345	MTOR	S935	S931C	931	Missense	distal	-4	no	11.289	9.464	EPSD	COSMIC	6.822	Down-regulation
Atypical_PIKK_FRAP_MTOR_ST	Q9UQ35	SRRM2	P42345	MTOR	S937	S931C	931	Missense	distal	-6	no	9.099	9.333	EPSD	COSMIC	6.822	Up-regulation
Atypical_PIKK_FRAP_MTOR_ST	Q9UQ35	SRRM2	P42345	MTOR	S954	N958S	958	Missense	distal	4	no	10.223	10.697	EPSD	COSMIC	6.822	Up-regulation
Atypical_PIKK_FRAP_MTOR_ST	Q9UQ35	SRRM2	P42345	MTOR	S974	P981L	981	Missense	distal	7	no	14.879	15.835	EPSD	COSMIC	6.822	Up-regulation
Atypical_PIKK_FRAP_MTOR_ST	Q9UQ35	SRRM2	P42345	MTOR	T983	P981L	981	Missense	proximal	-2	no	7.957	7.467	EPSD	COSMIC	6.822	Down-regulation
Atypical_PIKK_FRAP_MTOR_ST	Q9UQ35	SRRM2	P42345	MTOR	T983	T983A	983	Missense	central	0	yes	7.957	0.000	EPSD	COSMIC	6.822	Loss
Atypical_PIKK_FRAP_MTOR_ST	Q9UQ35	SRRM2	P42345	MTOR	S994	Y996C	996	Missense	proximal	2	no	8.813	9.004	EPSD	COSMIC	6.822	Up-regulation
Atypical_PIKK_FRAP_MTOR_ST	Q9UQ35	SRRM2	P42345	MTOR	T1003	Y996C	996	Missense	distal	-7	no	7.281	5.515	EPSD	COSMIC	6.822	Loss
Atypical_PIKK_FRAP_MTOR_ST	Q9UQ35	SRRM2	P42345	MTOR	T1003	P1004Q	1004	Missense	proximal	1	no	7.281	-1.333	EPSD	COSMIC	6.822	Loss
Atypical_PIKK_FRAP_MTOR_ST	Q9UQ35	SRRM2	P42345	MTOR	S1014	P1017S	1017	Missense	distal	3	no	8.752	8.767	EPSD	COSMIC;CCLE	6.822	Up-regulation
Atypical_PIKK_FRAP_MTOR_ST	Q9UQ35	SRRM2	P42345	MTOR	S1093	R1098Q	1098	Missense	distal	5	no	10.087	9.280	EPSD	COSMIC	6.822	Down-regulation
Atypical_PIKK_FRAP_MTOR_ST	Q9UQ35	SRRM2	P42345	MTOR	S1103	S1101F	1101	Missense	proximal	-2	no	8.453	8.631	EPSD	COSMIC	6.822	Up-regulation
Atypical_PIKK_FRAP_MTOR_ST	Q9UQ35	SRRM2	P42345	MTOR	S1103	S1103Y	1103	Missense	central	0	yes	8.453	0.000	EPSD	COSMIC	6.822	Loss
Atypical_PIKK_FRAP_MTOR_ST	Q9UQ35	SRRM2	P42345	MTOR	S1103	R1098Q	1098	Missense	distal	-5	no	8.453	8.367	EPSD	COSMIC	6.822	Down-regulation
Atypical_PIKK_FRAP_MTOR_ST	Q9UQ35	SRRM2	P42345	MTOR	S1144	S1144L	1144	Missense	central	0	yes	9.835	0.000	EPSD	COSMIC	6.822	Loss
Atypical_PIKK_FRAP_MTOR_ST	Q9UQ35	SRRM2	P42345	MTOR	S1157	S1152F	1152	Missense	distal	-5	no	8.247	8.254	EPSD	COSMIC	6.822	Up-regulation
Atypical_PIKK_FRAP_MTOR_ST	Q9UQ35	SRRM2	P42345	MTOR	S1179	D1185G	1185	Missense	distal	6	no	7.467	7.680	EPSD	COSMIC	6.822	Up-regulation
Atypical_PIKK_FRAP_MTOR_ST	Q9UQ35	SRRM2	P42345	MTOR	S1179	S1179P	1179	Missense	central	0	yes	7.467	0.000	EPSD	COSMIC	6.822	Loss
Atypical_PIKK_FRAP_MTOR_ST	Q9UQ35	SRRM2	P42345	MTOR	S1179	A1176V	1176	Missense	distal	-3	no	7.467	8.097	EPSD	COSMIC	6.822	Up-regulation
Atypical_PIKK_FRAP_MTOR_ST	Q9UQ35	SRRM2	P42345	MTOR	T1208	P1209L	1209	Missense	proximal	1	no	9.552	3.583	EPSD	COSMIC	6.822	Loss
Atypical_PIKK_FRAP_MTOR_ST	Q9UQ35	SRRM2	P42345	MTOR	T1208	P1209S	1209	Missense	proximal	1	no	9.552	1.028	EPSD	COSMIC	6.822	Loss
Atypical_PIKK_FRAP_MTOR_ST	Q9UQ35	SRRM2	P42345	MTOR	S1219	G1217W	1217	Missense	proximal	-2	no	7.728	6.572	EPSD	COSMIC	6.822	Loss
Atypical_PIKK_FRAP_MTOR_ST	Q9UQ35	SRRM2	P42345	MTOR	S1219	E1224Q	1224	Missense	distal	5	no	7.728	8.296	EPSD	COSMIC	6.822	Up-regulation
Atypical_PIKK_FRAP_MTOR_ST	Q9UQ35	SRRM2	P42345	MTOR	S1219	G1217R	1217	Missense	proximal	-2	no	7.728	6.870	EPSD	COSMIC	6.822	Down-regulation
Atypical_PIKK_FRAP_MTOR_ST	Q9UQ35	SRRM2	P42345	MTOR	S1271	N1267D	1267	Missense	distal	-4	no	6.669	8.830	EPSD	COSMIC	6.822	Gain
Atypical_PIKK_FRAP_MTOR_ST	Q9UQ35	SRRM2	P42345	MTOR	S1387	K1393R	1393	Missense	distal	6	no	9.596	8.509	EPSD	COSMIC	6.822	Down-regulation
Atypical_PIKK_FRAP_MTOR_ST	Q9UQ35	SRRM2	P42345	MTOR	T1413	S1415L	1415	Missense	proximal	2	no	7.731	7.536	EPSD	COSMIC	6.822	Down-regulation
Atypical_PIKK_FRAP_MTOR_ST	Q9UQ35	SRRM2	P42345	MTOR	T1413	E1417K	1417	Missense	distal	4	no	7.731	7.692	EPSD	COSMIC	6.822	Down-regulation
Atypical_PIKK_FRAP_MTOR_ST	Q9UQ35	SRRM2	P42345	MTOR	T1413	V1410I	1410	Missense	distal	-3	no	7.731	8.030	EPSD	COSMIC	6.822	Up-regulation
Atypical_PIKK_FRAP_MTOR_ST	Q9UQ35	SRRM2	P42345	MTOR	T1413	S1419R	1419	Missense	distal	6	no	7.731	5.908	EPSD	COSMIC;GDSC;CCLE	6.822	Loss
Atypical_PIKK_FRAP_MTOR_ST	Q9UQ35	SRRM2	P42345	MTOR	S1423	G1430D	1430	Missense	distal	7	no	6.768	6.946	EPSD	COSMIC	6.822	Gain
Atypical_PIKK_FRAP_MTOR_ST	Q9UQ35	SRRM2	P42345	MTOR	S1423	S1419R	1419	Missense	distal	-4	no	6.768	6.883	EPSD	COSMIC;GDSC;CCLE	6.822	Gain
Atypical_PIKK_FRAP_MTOR_ST	Q9UQ35	SRRM2	P42345	MTOR	S1424	G1430D	1430	Missense	distal	6	no	11.400	11.187	EPSD	COSMIC	6.822	Down-regulation
Atypical_PIKK_FRAP_MTOR_ST	Q9UQ35	SRRM2	P42345	MTOR	S1424	E1417K	1417	Missense	distal	-7	no	11.400	11.191	EPSD	COSMIC	6.822	Down-regulation
Atypical_PIKK_FRAP_MTOR_ST	Q9UQ35	SRRM2	P42345	MTOR	S1424	S1419R	1419	Missense	distal	-5	no	11.400	11.542	EPSD	COSMIC;GDSC;CCLE	6.822	Up-regulation
Atypical_PIKK_FRAP_MTOR_ST	Q9UQ35	SRRM2	P42345	MTOR	S1444	S1444F	1444	Missense	central	0	yes	12.094	0.000	EPSD	COSMIC;GDSC;CCLE	6.822	Loss
Atypical_PIKK_FRAP_MTOR_ST	Q9UQ35	SRRM2	P42345	MTOR	S1444	R1437S	1437	Missense	distal	-7	no	12.094	12.853	EPSD	COSMIC	6.822	Up-regulation
Atypical_PIKK_FRAP_MTOR_ST	Q9UQ35	SRRM2	P42345	MTOR	S1444	R1437K	1437	Missense	distal	-7	no	12.094	12.239	EPSD	COSMIC	6.822	Up-regulation
Atypical_PIKK_FRAP_MTOR_ST	Q9UQ35	SRRM2	P42345	MTOR	T1453	P1454L	1454	Missense	proximal	1	no	11.406	5.437	EPSD	COSMIC	6.822	Loss
Atypical_PIKK_FRAP_MTOR_ST	Q9UQ35	SRRM2	P42345	MTOR	T1472	R1475G	1475	Missense	distal	3	no	11.668	13.016	EPSD	COSMIC	6.822	Up-regulation
Atypical_PIKK_FRAP_MTOR_ST	Q9UQ35	SRRM2	P42345	MTOR	T1472	S1474F	1474	Missense	proximal	2	no	11.668	9.934	EPSD	COSMIC	6.822	Down-regulation
Atypical_PIKK_FRAP_MTOR_ST	Q9UQ35	SRRM2	P42345	MTOR	S1483	S1483F	1483	Missense	central	0	yes	7.968	0.000	EPSD	COSMIC	6.822	Loss
Atypical_PIKK_FRAP_MTOR_ST	Q9UQ35	SRRM2	P42345	MTOR	T1492	R1498H	1498	Missense	distal	6	no	7.770	8.086	EPSD	COSMIC;GDSC;CCLE	6.822	Up-regulation
Atypical_PIKK_FRAP_MTOR_ST	Q9UQ35	SRRM2	P42345	MTOR	S1499	R1498H	1498	Missense	proximal	-1	no	12.458	12.499	EPSD	COSMIC;GDSC;CCLE	6.822	Up-regulation
Atypical_PIKK_FRAP_MTOR_ST	Q9UQ35	SRRM2	P42345	MTOR	S1499	S1502F	1502	Missense	distal	3	no	12.458	12.862	EPSD	COSMIC	6.822	Up-regulation
Atypical_PIKK_FRAP_MTOR_ST	Q9UQ35	SRRM2	P42345	MTOR	S1502	R1498H	1498	Missense	distal	-4	no	8.077	6.884	EPSD	COSMIC;GDSC;CCLE	6.822	Down-regulation
Atypical_PIKK_FRAP_MTOR_ST	Q9UQ35	SRRM2	P42345	MTOR	S1502	S1502F	1502	Missense	central	0	yes	8.077	0.000	EPSD	COSMIC	6.822	Loss
Atypical_PIKK_FRAP_MTOR_ST	Q9UQ35	SRRM2	P42345	MTOR	T1531	D1524H	1524	Missense	distal	-7	no	13.389	12.036	EPSD	COSMIC	6.822	Down-regulation
Atypical_PIKK_FRAP_MTOR_ST	Q9UQ35	SRRM2	P42345	MTOR	S1552	D1546G	1546	Missense	distal	-6	no	8.000	8.017	EPSD	COSMIC	6.822	Up-regulation
Atypical_PIKK_FRAP_MTOR_ST	Q9UQ35	SRRM2	P42345	MTOR	T1571	R1574W	1574	Missense	distal	3	no	9.712	7.952	EPSD	COSMIC	6.822	Down-regulation
Atypical_PIKK_FRAP_MTOR_ST	Q9UQ35	SRRM2	P42345	MTOR	T1571	R1578Q	1578	Missense	distal	7	no	9.712	9.313	EPSD	COSMIC;GDSC	6.822	Down-regulation
Atypical_PIKK_FRAP_MTOR_ST	Q9UQ35	SRRM2	P42345	MTOR	S1582	R1578Q	1578	Missense	distal	-4	no	10.483	9.986	EPSD	COSMIC;GDSC	6.822	Down-regulation
Atypical_PIKK_FRAP_MTOR_ST	Q9UQ35	SRRM2	P42345	MTOR	S1592	R1595H	1595	Missense	distal	3	no	8.450	8.620	EPSD	COSMIC	6.822	Up-regulation
Atypical_PIKK_FRAP_MTOR_ST	Q9UQ35	SRRM2	P42345	MTOR	S1600	S1601P	1601	Missense	proximal	1	no	1.931	10.455	EPSD	COSMIC	6.822	Gain
Atypical_PIKK_FRAP_MTOR_ST	Q9UQ35	SRRM2	P42345	MTOR	S1621	P1622L	1622	Missense	proximal	1	no	8.173	2.204	EPSD	COSMIC	6.822	Loss
Atypical_PIKK_FRAP_MTOR_ST	Q9UQ35	SRRM2	P42345	MTOR	S1648	T1655I	1655	Missense	distal	7	no	14.914	16.234	EPSD	COSMIC	6.822	Up-regulation
Atypical_PIKK_FRAP_MTOR_ST	Q9UQ35	SRRM2	P42345	MTOR	S1654	E1656V	1656	Missense	proximal	2	no	9.153	8.299	EPSD	COSMIC	6.822	Down-regulation
Atypical_PIKK_FRAP_MTOR_ST	Q9UQ35	SRRM2	P42345	MTOR	S1654	T1655I	1655	Missense	proximal	1	no	9.153	10.367	EPSD	COSMIC	6.822	Up-regulation
Atypical_PIKK_FRAP_MTOR_ST	Q9UQ35	SRRM2	P42345	MTOR	S1658	E1656V	1656	Missense	proximal	-2	no	11.333	11.325	EPSD	COSMIC	6.822	Down-regulation
Atypical_PIKK_FRAP_MTOR_ST	Q9UQ35	SRRM2	P42345	MTOR	S1658	T1655I	1655	Missense	distal	-3	no	11.333	12.208	EPSD	COSMIC	6.822	Up-regulation
Atypical_PIKK_FRAP_MTOR_ST	Q9UQ35	SRRM2	P42345	MTOR	S1675	S1674P	1674	Missense	proximal	-1	no	7.276	7.208	EPSD	COSMIC;GDSC;CCLE	6.822	Down-regulation
Atypical_PIKK_FRAP_MTOR_ST	Q9UQ35	SRRM2	P42345	MTOR	S1675	P1676Q	1676	Missense	proximal	1	no	7.276	-1.338	EPSD	COSMIC	6.822	Loss
Atypical_PIKK_FRAP_MTOR_ST	Q9UQ35	SRRM2	P42345	MTOR	T1684	R1688H	1688	Missense	distal	4	no	8.317	8.058	EPSD	COSMIC	6.822	Down-regulation
Atypical_PIKK_FRAP_MTOR_ST	Q9UQ35	SRRM2	P42345	MTOR	S1694	E1696K	1696	Missense	proximal	2	no	11.187	10.282	EPSD	COSMIC	6.822	Down-regulation
Atypical_PIKK_FRAP_MTOR_ST	Q9UQ35	SRRM2	P42345	MTOR	S1694	R1688H	1688	Missense	distal	-6	no	11.187	10.380	EPSD	COSMIC	6.822	Down-regulation
Atypical_PIKK_FRAP_MTOR_ST	Q9UQ35	SRRM2	P42345	MTOR	S1694	R1699K	1699	Missense	distal	5	no	11.187	9.866	EPSD	COSMIC	6.822	Down-regulation
Atypical_PIKK_FRAP_MTOR_ST	Q9UQ35	SRRM2	P42345	MTOR	S1713	A1710V	1710	Missense	distal	-3	no	8.910	9.540	EPSD	COSMIC;GDSC;CCLE	6.822	Up-regulation
Atypical_PIKK_FRAP_MTOR_ST	Q9UQ35	SRRM2	P42345	MTOR	S1713	R1706K	1706	Missense	distal	-7	no	8.910	9.056	EPSD	COSMIC	6.822	Up-regulation
Atypical_PIKK_FRAP_MTOR_ST	Q9UQ35	SRRM2	P42345	MTOR	T1720	P1721S	1721	Missense	proximal	1	no	7.016	-1.508	EPSD	COSMIC	6.822	Loss
Atypical_PIKK_FRAP_MTOR_ST	Q9UQ35	SRRM2	P42345	MTOR	S1727	E1734K	1734	Missense	distal	7	no	10.374	10.470	EPSD	COSMIC	6.822	Up-regulation
Atypical_PIKK_FRAP_MTOR_ST	Q9UQ35	SRRM2	P42345	MTOR	S1727	P1721S	1721	Missense	distal	-6	no	10.374	10.353	EPSD	COSMIC	6.822	Down-regulation
Atypical_PIKK_FRAP_MTOR_ST	Q9UQ35	SRRM2	P42345	MTOR	S1732	E1734K	1734	Missense	proximal	2	no	10.028	9.123	EPSD	COSMIC	6.822	Down-regulation
Atypical_PIKK_FRAP_MTOR_ST	Q9UQ35	SRRM2	P42345	MTOR	S1732	E1737K	1737	Missense	distal	5	no	10.028	10.083	EPSD	COSMIC	6.822	Up-regulation
Atypical_PIKK_FRAP_MTOR_ST	Q9UQ35	SRRM2	P42345	MTOR	S1762	K1766T	1766	Missense	distal	4	no	10.436	10.774	EPSD	COSMIC	6.822	Up-regulation
Atypical_PIKK_FRAP_MTOR_ST	Q9UQ35	SRRM2	P42345	MTOR	S1762	R1758W	1758	Missense	distal	-4	no	10.436	10.546	EPSD	COSMIC	6.822	Up-regulation
Atypical_PIKK_FRAP_MTOR_ST	Q9UQ35	SRRM2	P42345	MTOR	S1762	R1761L	1761	Missense	proximal	-1	no	10.436	10.396	EPSD	COSMIC;CCLE	6.822	Down-regulation
Atypical_PIKK_FRAP_MTOR_ST	Q9UQ35	SRRM2	P42345	MTOR	S1762	G1760V	1760	Missense	proximal	-2	no	10.436	9.788	EPSD	COSMIC	6.822	Down-regulation
Atypical_PIKK_FRAP_MTOR_ST	Q9UQ35	SRRM2	P42345	MTOR	S1764	K1766T	1766	Missense	proximal	2	no	10.855	10.863	EPSD	COSMIC	6.822	Up-regulation
Atypical_PIKK_FRAP_MTOR_ST	Q9UQ35	SRRM2	P42345	MTOR	S1764	R1758W	1758	Missense	distal	-6	no	10.855	11.228	EPSD	COSMIC	6.822	Up-regulation
Atypical_PIKK_FRAP_MTOR_ST	Q9UQ35	SRRM2	P42345	MTOR	S1764	R1761L	1761	Missense	distal	-3	no	10.855	10.924	EPSD	COSMIC;CCLE	6.822	Up-regulation
Atypical_PIKK_FRAP_MTOR_ST	Q9UQ35	SRRM2	P42345	MTOR	S1764	G1760V	1760	Missense	distal	-4	no	10.855	10.739	EPSD	COSMIC	6.822	Down-regulation
Atypical_PIKK_FRAP_MTOR_ST	Q9UQ35	SRRM2	P42345	MTOR	S1824	E1829K	1829	Missense	distal	5	no	8.458	8.513	EPSD	COSMIC	6.822	Up-regulation
Atypical_PIKK_FRAP_MTOR_ST	Q9UQ35	SRRM2	P42345	MTOR	T1844	R1839S	1839	Missense	distal	-5	no	10.177	10.036	EPSD	COSMIC	6.822	Down-regulation
Atypical_PIKK_FRAP_MTOR_ST	Q9UQ35	SRRM2	P42345	MTOR	T1844	R1838Q	1838	Missense	distal	-6	no	10.177	9.913	EPSD	COSMIC	6.822	Down-regulation
Atypical_PIKK_FRAP_MTOR_ST	Q9UQ35	SRRM2	P42345	MTOR	S1857	R1855S	1855	Missense	proximal	-2	no	8.858	8.985	EPSD	COSMIC	6.822	Up-regulation
Atypical_PIKK_FRAP_MTOR_ST	Q9UQ35	SRRM2	P42345	MTOR	S1857	R1855C	1855	Missense	proximal	-2	no	8.858	9.135	EPSD	COSMIC;GDSC;CCLE	6.822	Up-regulation
Atypical_PIKK_FRAP_MTOR_ST	Q9UQ35	SRRM2	P42345	MTOR	S1857	R1853H	1853	Missense	distal	-4	no	8.858	7.664	EPSD	COSMIC	6.822	Down-regulation
Atypical_PIKK_FRAP_MTOR_ST	Q9UQ35	SRRM2	P42345	MTOR	S1893	R1899L	1899	Missense	distal	6	no	11.074	11.707	EPSD	COSMIC	6.822	Up-regulation
Atypical_PIKK_FRAP_MTOR_ST	Q9UQ35	SRRM2	P42345	MTOR	S1893	P1894Q	1894	Missense	proximal	1	no	11.074	2.460	EPSD	COSMIC	6.822	Loss
Atypical_PIKK_FRAP_MTOR_ST	Q9UQ35	SRRM2	P42345	MTOR	S1893	V1895A	1895	Missense	proximal	2	no	11.074	10.326	EPSD	COSMIC	6.822	Down-regulation
Atypical_PIKK_FRAP_MTOR_ST	Q9UQ35	SRRM2	P42345	MTOR	S1893	R1886H	1886	Missense	distal	-7	no	11.074	10.725	EPSD	COSMIC	6.822	Down-regulation
Atypical_PIKK_FRAP_MTOR_ST	Q9UQ35	SRRM2	P42345	MTOR	S1893	P1894S	1894	Missense	proximal	1	no	11.074	2.550	EPSD	COSMIC	6.822	Loss
Atypical_PIKK_FRAP_MTOR_ST	Q9UQ35	SRRM2	P42345	MTOR	S1916	R1921G	1921	Missense	distal	5	no	9.550	9.220	EPSD	COSMIC	6.822	Down-regulation
Atypical_PIKK_FRAP_MTOR_ST	Q9UQ35	SRRM2	P42345	MTOR	T1927	R1921G	1921	Missense	distal	-6	no	9.658	9.672	EPSD	COSMIC	6.822	Up-regulation
Atypical_PIKK_FRAP_MTOR_ST	Q9UQ35	SRRM2	P42345	MTOR	T1939	R1938T	1938	Missense	proximal	-1	no	10.018	10.126	EPSD	COSMIC	6.822	Up-regulation
Atypical_PIKK_FRAP_MTOR_ST	Q9UQ35	SRRM2	P42345	MTOR	T1939	R1945H	1945	Missense	distal	6	no	10.018	10.335	EPSD	COSMIC	6.822	Up-regulation
Atypical_PIKK_FRAP_MTOR_ST	Q9UQ35	SRRM2	P42345	MTOR	T1939	R1944H	1944	Missense	distal	5	no	10.018	10.323	EPSD	COSMIC	6.822	Up-regulation
Atypical_PIKK_FRAP_MTOR_ST	Q9UQ35	SRRM2	P42345	MTOR	T1950	R1947L	1947	Missense	distal	-3	no	11.438	11.507	EPSD	COSMIC	6.822	Up-regulation
Atypical_PIKK_FRAP_MTOR_ST	Q9UQ35	SRRM2	P42345	MTOR	T1950	R1945H	1945	Missense	distal	-5	no	11.438	11.442	EPSD	COSMIC	6.822	Up-regulation
Atypical_PIKK_FRAP_MTOR_ST	Q9UQ35	SRRM2	P42345	MTOR	T1950	R1944H	1944	Missense	distal	-6	no	11.438	10.631	EPSD	COSMIC	6.822	Down-regulation
Atypical_PIKK_FRAP_MTOR_ST	Q9UQ35	SRRM2	P42345	MTOR	T1950	R1947H	1947	Missense	distal	-3	no	11.438	10.691	EPSD	COSMIC	6.822	Down-regulation
Atypical_PIKK_FRAP_MTOR_ST	Q9UQ35	SRRM2	P42345	MTOR	T1950	P1951S	1951	Missense	proximal	1	no	11.438	2.914	EPSD	COSMIC	6.822	Loss
Atypical_PIKK_FRAP_MTOR_ST	Q9UQ35	SRRM2	P42345	MTOR	T1962	R1969Q	1969	Missense	distal	7	no	7.123	6.724	EPSD	COSMIC	6.822	Loss
Atypical_PIKK_FRAP_MTOR_ST	Q9UQ35	SRRM2	P42345	MTOR	T1962	S1958F	1958	Missense	distal	-4	no	7.123	7.148	EPSD	COSMIC	6.822	Up-regulation
Atypical_PIKK_FRAP_MTOR_ST	Q9UQ35	SRRM2	P42345	MTOR	T1962	R1967K	1967	Missense	distal	5	no	7.123	5.802	EPSD	COSMIC	6.822	Loss
Atypical_PIKK_FRAP_MTOR_ST	Q9UQ35	SRRM2	P42345	MTOR	S1975	R1969Q	1969	Missense	distal	-6	no	9.092	8.827	EPSD	COSMIC	6.822	Down-regulation
Atypical_PIKK_FRAP_MTOR_ST	Q9UQ35	SRRM2	P42345	MTOR	S1999	S1996F	1996	Missense	distal	-3	no	9.503	9.575	EPSD	COSMIC	6.822	Up-regulation
Atypical_PIKK_FRAP_MTOR_ST	Q9UQ35	SRRM2	P42345	MTOR	S2011	S2018F	2018	Missense	distal	7	no	9.536	10.117	EPSD	COSMIC	6.822	Up-regulation
Atypical_PIKK_FRAP_MTOR_ST	Q9UQ35	SRRM2	P42345	MTOR	S2011	R2007H	2007	Missense	distal	-4	no	9.536	8.343	EPSD	COSMIC	6.822	Down-regulation
Atypical_PIKK_FRAP_MTOR_ST	Q9UQ35	SRRM2	P42345	MTOR	S2011	R2017C	2017	Missense	distal	6	no	9.536	9.663	EPSD	COSMIC	6.822	Up-regulation
Atypical_PIKK_FRAP_MTOR_ST	Q9UQ35	SRRM2	P42345	MTOR	S2011	R2009Q	2009	Missense	proximal	-2	no	9.536	9.876	EPSD	COSMIC	6.822	Up-regulation
Atypical_PIKK_FRAP_MTOR_ST	Q9UQ35	SRRM2	P42345	MTOR	T2022	S2018F	2018	Missense	distal	-4	no	8.270	8.294	EPSD	COSMIC	6.822	Up-regulation
Atypical_PIKK_FRAP_MTOR_ST	Q9UQ35	SRRM2	P42345	MTOR	T2022	R2017C	2017	Missense	distal	-5	no	8.270	8.394	EPSD	COSMIC	6.822	Up-regulation
Atypical_PIKK_FRAP_MTOR_ST	Q9UQ35	SRRM2	P42345	MTOR	T2034	R2033Q	2033	Missense	proximal	-1	no	8.206	8.225	EPSD	COSMIC	6.822	Up-regulation
Atypical_PIKK_FRAP_MTOR_ST	Q9UQ35	SRRM2	P42345	MTOR	T2034	R2039C	2039	Missense	distal	5	no	8.206	7.991	EPSD	COSMIC	6.822	Down-regulation
Atypical_PIKK_FRAP_MTOR_ST	Q9UQ35	SRRM2	P42345	MTOR	S2046	A2049V	2049	Missense	distal	3	no	10.758	8.747	EPSD	COSMIC	6.822	Down-regulation
Atypical_PIKK_FRAP_MTOR_ST	Q9UQ35	SRRM2	P42345	MTOR	S2046	A2049G	2049	Missense	distal	3	no	10.758	10.771	EPSD	COSMIC	6.822	Up-regulation
Atypical_PIKK_FRAP_MTOR_ST	Q9UQ35	SRRM2	P42345	MTOR	S2046	A2049P	2049	Missense	distal	3	no	10.758	9.689	EPSD	COSMIC	6.822	Down-regulation
Atypical_PIKK_FRAP_MTOR_ST	Q9UQ35	SRRM2	P42345	MTOR	S2046	L2048V	2048	Missense	proximal	2	no	10.758	10.937	EPSD	COSMIC;GDSC;CCLE	6.822	Up-regulation
Atypical_PIKK_FRAP_MTOR_ST	Q9UQ35	SRRM2	P42345	MTOR	S2046	R2039C	2039	Missense	distal	-7	no	10.758	9.663	EPSD	COSMIC	6.822	Down-regulation
Atypical_PIKK_FRAP_MTOR_ST	Q9UQ35	SRRM2	P42345	MTOR	T2058	A2062D	2062	Missense	distal	4	no	11.832	12.235	EPSD	COSMIC	6.822	Up-regulation
Atypical_PIKK_FRAP_MTOR_ST	Q9UQ35	SRRM2	P42345	MTOR	T2058	T2058I	2058	Missense	central	0	yes	11.832	0.000	EPSD	COSMIC	6.822	Loss
Atypical_PIKK_FRAP_MTOR_ST	Q9UQ35	SRRM2	P42345	MTOR	S2067	A2074D	2074	Missense	distal	7	no	5.941	6.929	EPSD	COSMIC	6.822	Gain
Atypical_PIKK_FRAP_MTOR_ST	Q9UQ35	SRRM2	P42345	MTOR	S2071	P2073S	2073	Missense	proximal	2	no	11.651	11.157	EPSD	COSMIC	6.822	Down-regulation
Atypical_PIKK_FRAP_MTOR_ST	Q9UQ35	SRRM2	P42345	MTOR	S2071	R2078C	2078	Missense	distal	7	no	11.651	12.082	EPSD	COSMIC	6.822	Up-regulation
Atypical_PIKK_FRAP_MTOR_ST	Q9UQ35	SRRM2	P42345	MTOR	S2071	S2067P	2067	Missense	distal	-4	no	11.651	11.522	EPSD	COSMIC	6.822	Down-regulation
Atypical_PIKK_FRAP_MTOR_ST	Q9UQ35	SRRM2	P42345	MTOR	S2071	A2074D	2074	Missense	distal	3	no	11.651	9.922	EPSD	COSMIC	6.822	Down-regulation
Atypical_PIKK_FRAP_MTOR_ST	Q9UQ35	SRRM2	P42345	MTOR	S2071	R2078H	2078	Missense	distal	7	no	11.651	11.494	EPSD	COSMIC	6.822	Down-regulation
Atypical_PIKK_FRAP_MTOR_ST	Q9UQ35	SRRM2	P42345	MTOR	T2092	R2089Q	2089	Missense	distal	-3	no	10.428	9.820	EPSD	COSMIC	6.822	Down-regulation
Atypical_PIKK_FRAP_MTOR_ST	Q9UQ35	SRRM2	P42345	MTOR	T2144	T2144R	2144	Missense	central	0	yes	6.875	0.000	EPSD	COSMIC	6.822	Loss
Atypical_PIKK_FRAP_MTOR_ST	Q9UQ35	SRRM2	P42345	MTOR	T2144	S2142C	2142	Missense	proximal	-2	no	6.875	7.024	EPSD	COSMIC	6.822	Up-regulation
Atypical_PIKK_FRAP_MTOR_ST	Q9UQ35	SRRM2	P42345	MTOR	S2147	G2153S	2153	Missense	distal	6	no	8.217	8.287	EPSD	COSMIC	6.822	Up-regulation
Atypical_PIKK_FRAP_MTOR_ST	Q9UQ35	SRRM2	P42345	MTOR	S2147	T2144R	2144	Missense	distal	-3	no	8.217	9.003	EPSD	COSMIC	6.822	Up-regulation
Atypical_PIKK_FRAP_MTOR_ST	Q9UQ35	SRRM2	P42345	MTOR	S2147	S2142C	2142	Missense	distal	-5	no	8.217	8.483	EPSD	COSMIC	6.822	Up-regulation
Atypical_PIKK_FRAP_MTOR_ST	Q9UQ35	SRRM2	P42345	MTOR	T2261	A2267V	2267	Missense	distal	6	no	7.929	8.620	EPSD	COSMIC	6.822	Up-regulation
Atypical_PIKK_FRAP_MTOR_ST	Q9UQ35	SRRM2	P42345	MTOR	T2261	A2257S	2257	Missense	distal	-4	no	7.929	8.892	EPSD	COSMIC	6.822	Up-regulation
Atypical_PIKK_FRAP_MTOR_ST	Q9UQ35	SRRM2	P42345	MTOR	T2261	S2259C	2259	Missense	proximal	-2	no	7.929	8.078	EPSD	COSMIC	6.822	Up-regulation
Atypical_PIKK_FRAP_MTOR_ST	Q9UQ35	SRRM2	P42345	MTOR	S2272	A2267V	2267	Missense	distal	-5	no	8.642	8.552	EPSD	COSMIC	6.822	Down-regulation
Atypical_PIKK_FRAP_MTOR_ST	Q9UQ35	SRRM2	P42345	MTOR	S2272	P2279H	2279	Missense	distal	7	no	8.642	9.256	EPSD	COSMIC;GDSC;CCLE	6.822	Up-regulation
Atypical_PIKK_FRAP_MTOR_ST	Q9UQ35	SRRM2	P42345	MTOR	T2289	P2293S	2293	Missense	distal	4	no	8.413	8.669	EPSD	COSMIC	6.822	Up-regulation
Atypical_PIKK_FRAP_MTOR_ST	Q9UQ35	SRRM2	P42345	MTOR	T2289	P2290S	2290	Missense	proximal	1	no	8.413	-0.111	EPSD	COSMIC;GDSC;CCLE	6.822	Loss
Atypical_PIKK_FRAP_MTOR_ST	Q9UQ35	SRRM2	P42345	MTOR	T2289	D2286N	2286	Missense	distal	-3	no	8.413	8.838	EPSD	COSMIC	6.822	Up-regulation
Atypical_PIKK_FRAP_MTOR_ST	Q9UQ35	SRRM2	P42345	MTOR	S2382	P2386L	2386	Missense	distal	4	no	7.948	7.564	EPSD	COSMIC	6.822	Down-regulation
Atypical_PIKK_FRAP_MTOR_ST	Q9UQ35	SRRM2	P42345	MTOR	S2382	N2379K	2379	Missense	distal	-3	no	7.948	7.030	EPSD	COSMIC	6.822	Down-regulation
Atypical_PIKK_FRAP_MTOR_ST	Q9UQ35	SRRM2	P42345	MTOR	S2398	S2398L	2398	Missense	central	0	yes	9.346	0.000	EPSD	COSMIC	6.822	Loss
Atypical_PIKK_FRAP_MTOR_ST	Q9UQ35	SRRM2	P42345	MTOR	S2398	D2403H	2403	Missense	distal	5	no	9.346	10.608	EPSD	COSMIC	6.822	Up-regulation
Atypical_PIKK_FRAP_MTOR_ST	Q9UQ35	SRRM2	P42345	MTOR	S2398	P2400L	2400	Missense	proximal	2	no	9.346	8.657	EPSD	COSMIC	6.822	Down-regulation
Atypical_PIKK_FRAP_MTOR_ST	Q9UQ35	SRRM2	P42345	MTOR	S2426	R2423W	2423	Missense	distal	-3	no	9.327	9.111	EPSD	COSMIC	6.822	Down-regulation
Atypical_PIKK_FRAP_MTOR_ST	Q9UQ35	SRRM2	P42345	MTOR	S2545	S2549L	2549	Missense	distal	4	no	7.702	7.063	EPSD	COSMIC	6.822	Down-regulation
Atypical_PIKK_FRAP_MTOR_ST	Q9UQ35	SRRM2	P42345	MTOR	S2545	S2539F	2539	Missense	distal	-6	no	7.702	7.228	EPSD	COSMIC	6.822	Down-regulation
Atypical_PIKK_FRAP_MTOR_ST	Q9UQ35	SRRM2	P42345	MTOR	S2581	T2583P	2583	Missense	proximal	2	no	10.090	10.643	EPSD	COSMIC	6.822	Up-regulation
Atypical_PIKK_FRAP_MTOR_ST	Q9UQ35	SRRM2	P42345	MTOR	S2581	K2577M	2577	Missense	distal	-4	no	10.090	9.782	EPSD	COSMIC	6.822	Down-regulation
Atypical_PIKK_FRAP_MTOR_ST	Q9UQ35	SRRM2	P42345	MTOR	T2583	T2583P	2583	Missense	central	0	yes	8.259	0.000	EPSD	COSMIC	6.822	Loss
Atypical_PIKK_FRAP_MTOR_ST	Q9UQ35	SRRM2	P42345	MTOR	T2583	K2577M	2577	Missense	distal	-6	no	8.259	8.501	EPSD	COSMIC	6.822	Up-regulation
Atypical_PIKK_FRAP_MTOR_ST	Q9UQ35	SRRM2	P42345	MTOR	S2650	S2644L	2644	Missense	distal	-6	no	10.432	9.678	EPSD	COSMIC	6.822	Down-regulation
Atypical_PIKK_FRAP_MTOR_ST	Q9UQ35	SRRM2	P42345	MTOR	S2690	Y2693C	2693	Missense	distal	3	no	7.804	6.177	EPSD	COSMIC	6.822	Loss
Atypical_PIKK_FRAP_MTOR_ST	Q9UQ35	SRRM2	P42345	MTOR	S2690	S2684F	2684	Missense	distal	-6	no	7.804	7.329	EPSD	COSMIC	6.822	Down-regulation
Atypical_PIKK_FRAP_MTOR_ST	Q9UQ35	SRRM2	P42345	MTOR	S2694	Y2693C	2693	Missense	proximal	-1	no	10.965	11.149	EPSD	COSMIC	6.822	Up-regulation
Atypical_PIKK_FRAP_MTOR_ST	Q9UQ35	SRRM2	P42345	MTOR	S2694	R2699C	2699	Missense	distal	5	no	10.965	10.749	EPSD	COSMIC;GDSC;CCLE	6.822	Down-regulation
Atypical_PIKK_FRAP_MTOR_ST	Q9UQ35	SRRM2	P42345	MTOR	S2702	R2699C	2699	Missense	distal	-3	no	7.488	6.776	EPSD	COSMIC;GDSC;CCLE	6.822	Loss
Atypical_PIKK_FRAP_MTOR_ST	Q9UQ35	SRRM2	P42345	MTOR	S2706	R2699C	2699	Missense	distal	-7	no	7.986	6.891	EPSD	COSMIC;GDSC;CCLE	6.822	Down-regulation
Atypical_PIKK_FRAP_MTOR_ST	Q9UQ35	SRRM2	P42345	MTOR	T2738	P2739S	2739	Missense	proximal	1	no	14.945	6.421	EPSD	COSMIC	6.822	Loss
Atypical_PIKK_FRAP_MTOR_ST	Q9UQ35	SRRM2	P42345	MTOR	S2740	P2739S	2739	Missense	proximal	-1	no	15.970	16.039	EPSD	COSMIC	6.822	Up-regulation
Atypical_PIKK_FRAP_MTOR_ST	Q9UQ35	SRRM2	P42345	MTOR	S2740	R2747C	2747	Missense	distal	7	no	15.970	16.401	EPSD	COSMIC	6.822	Up-regulation
Atypical_PIKK_FRAP_MTOR_ST	Q9UQ35	SRRM2	P42345	MTOR	S2751	R2747C	2747	Missense	distal	-4	no	13.770	11.830	EPSD	COSMIC	6.822	Down-regulation
Atypical_PIKK_FRAP_MTOR_ST	P42345	MTOR	P42345	MTOR	T314	G307R	307	Missense	distal	-7	no	9.077	8.880	EPSD	COSMIC	6.822	Down-regulation
Atypical_PIKK_FRAP_MTOR_ST	P42345	MTOR	P42345	MTOR	T314	T314N	314	Missense	central	0	yes	9.077	0.000	EPSD	COSMIC	6.822	Loss
Atypical_PIKK_FRAP_MTOR_ST	P42345	MTOR	P42345	MTOR	T314	F319L	319	Missense	distal	5	no	9.077	9.977	EPSD	COSMIC	6.822	Up-regulation
Atypical_PIKK_FRAP_MTOR_ST	P42345	MTOR	P42345	MTOR	T314	Q320H	320	Missense	distal	6	no	9.077	9.009	EPSD	COSMIC	6.822	Down-regulation
Atypical_PIKK_FRAP_MTOR_ST	P42345	MTOR	P42345	MTOR	T572	A566T	566	Missense	distal	-6	no	6.580	6.859	EPSD	COSMIC	6.822	Gain
Atypical_PIKK_FRAP_MTOR_ST	P42345	MTOR	P42345	MTOR	S719	S720I	720	Missense	proximal	1	no	3.985	7.450	EPSD	COSMIC	6.822	Gain
Atypical_PIKK_FRAP_MTOR_ST	P42345	MTOR	P42345	MTOR	S720	G716S	716	Missense	distal	-4	no	7.913	8.480	EPSD	COSMIC	6.822	Up-regulation
Atypical_PIKK_FRAP_MTOR_ST	P42345	MTOR	P42345	MTOR	S720	R717L	717	Missense	distal	-3	no	7.913	7.982	EPSD	COSMIC	6.822	Up-regulation
Atypical_PIKK_FRAP_MTOR_ST	P42345	MTOR	P42345	MTOR	S720	V715M	715	Missense	distal	-5	no	7.913	7.969	EPSD	COSMIC	6.822	Up-regulation
Atypical_PIKK_FRAP_MTOR_ST	P42345	MTOR	P42345	MTOR	S720	M727V	727	Missense	distal	7	no	7.913	8.286	EPSD	COSMIC	6.822	Up-regulation
Atypical_PIKK_FRAP_MTOR_ST	P42345	MTOR	P42345	MTOR	S720	G716D	716	Missense	distal	-4	no	7.913	9.509	EPSD	COSMIC	6.822	Up-regulation
Atypical_PIKK_FRAP_MTOR_ST	P42345	MTOR	P42345	MTOR	S720	S720I	720	Missense	central	0	yes	7.913	0.000	EPSD	COSMIC	6.822	Loss
Atypical_PIKK_FRAP_MTOR_ST	P42345	MTOR	P42345	MTOR	S1166	Q1165H	1165	Missense	proximal	-1	no	8.242	8.264	EPSD	COSMIC	6.822	Up-regulation
Atypical_PIKK_FRAP_MTOR_ST	P42345	MTOR	P42345	MTOR	S1166	R1161Q	1161	Missense	distal	-5	no	8.242	8.157	EPSD	COSMIC;CCLE	6.822	Down-regulation
Atypical_PIKK_FRAP_MTOR_ST	P42345	MTOR	P42345	MTOR	S1166	R1170H	1170	Missense	distal	4	no	8.242	7.983	EPSD	COSMIC	6.822	Down-regulation
Atypical_PIKK_FRAP_MTOR_ST	P42345	MTOR	P42345	MTOR	S1166	R1170P	1170	Missense	distal	4	no	8.242	8.559	EPSD	COSMIC	6.822	Up-regulation
Atypical_PIKK_FRAP_MTOR_ST	P42345	MTOR	P42345	MTOR	S1179	K1186N	1186	Missense	distal	7	no	6.669	7.621	EPSD	COSMIC	6.822	Gain
Atypical_PIKK_FRAP_MTOR_ST	P42345	MTOR	P42345	MTOR	S1296	S1297L	1297	Missense	proximal	1	no	5.901	8.456	EPSD	COSMIC	6.822	Gain
Atypical_PIKK_FRAP_MTOR_ST	P42345	MTOR	P42345	MTOR	S1297	S1297L	1297	Missense	central	0	yes	8.086	0.000	EPSD	COSMIC	6.822	Loss
Atypical_PIKK_FRAP_MTOR_ST	P42345	MTOR	P42345	MTOR	S1297	R1301C	1301	Missense	distal	4	no	8.086	7.873	EPSD	COSMIC	6.822	Down-regulation
Atypical_PIKK_FRAP_MTOR_ST	P42345	MTOR	P42345	MTOR	S1297	L1292M	1292	Missense	distal	-5	no	8.086	8.104	EPSD	COSMIC	6.822	Up-regulation
Atypical_PIKK_FRAP_MTOR_ST	P42345	MTOR	P42345	MTOR	S1297	S1295L	1295	Missense	proximal	-2	no	8.086	7.952	EPSD	COSMIC	6.822	Down-regulation
Atypical_PIKK_FRAP_MTOR_ST	P42345	MTOR	P42345	MTOR	S1843	A1836T	1836	Missense	distal	-7	no	7.462	8.353	EPSD	COSMIC	6.822	Up-regulation
Atypical_PIKK_FRAP_MTOR_ST	P42345	MTOR	P42345	MTOR	S1843	T1844I	1844	Missense	proximal	1	no	7.462	8.675	EPSD	COSMIC	6.822	Up-regulation
Atypical_PIKK_FRAP_MTOR_ST	P42345	MTOR	P42345	MTOR	S1843	T1837N	1837	Missense	distal	-6	no	7.462	6.834	EPSD	COSMIC;CCLE	6.822	Down-regulation
Atypical_PIKK_FRAP_MTOR_ST	P42345	MTOR	P42345	MTOR	S1843	E1845V	1845	Missense	proximal	2	no	7.462	6.608	EPSD	COSMIC	6.822	Loss
Atypical_PIKK_FRAP_MTOR_ST	P42345	MTOR	P42345	MTOR	S1843	T1844A	1844	Missense	proximal	1	no	7.462	4.851	EPSD	COSMIC	6.822	Loss
Atypical_PIKK_FRAP_MTOR_ST	P42345	MTOR	P42345	MTOR	S1843	T1844S	1844	Missense	proximal	1	no	7.462	5.210	EPSD	COSMIC	6.822	Loss
Atypical_PIKK_FRAP_MTOR_ST	P42345	MTOR	P42345	MTOR	S1843	E1850D	1850	Missense	distal	7	no	7.462	8.474	EPSD	COSMIC	6.822	Up-regulation
Atypical_PIKK_FRAP_MTOR_ST	P42345	MTOR	P42345	MTOR	T1948	R1950K	1950	Missense	proximal	2	no	10.116	11.762	EPSD	COSMIC	6.822	Up-regulation
Atypical_PIKK_FRAP_MTOR_ST	P42345	MTOR	P42345	MTOR	T1948	I1946T	1946	Missense	proximal	-2	no	10.116	10.620	EPSD	COSMIC	6.822	Up-regulation
Atypical_PIKK_FRAP_MTOR_ST	P42345	MTOR	P42345	MTOR	T1948	D1947H	1947	Missense	proximal	-1	no	10.116	10.057	EPSD	COSMIC	6.822	Down-regulation
Atypical_PIKK_FRAP_MTOR_ST	P42345	MTOR	P42345	MTOR	T1948	R1955C	1955	Missense	distal	7	no	10.116	10.546	EPSD	COSMIC	6.822	Up-regulation
Atypical_PIKK_FRAP_MTOR_ST	P42345	MTOR	P42345	MTOR	T2214	S2215P	2215	Missense	proximal	1	no	-1.336	7.188	EPSD	COSMIC	6.822	Gain
Atypical_PIKK_FRAP_MTOR_ST	P42345	MTOR	P42345	MTOR	S2221	L2216I	2216	Missense	distal	-5	no	8.517	8.606	EPSD	COSMIC	6.822	Up-regulation
Atypical_PIKK_FRAP_MTOR_ST	P42345	MTOR	P42345	MTOR	S2221	S2215P	2215	Missense	distal	-6	no	8.517	8.538	EPSD	COSMIC	6.822	Up-regulation
Atypical_PIKK_FRAP_MTOR_ST	P42345	MTOR	P42345	MTOR	S2221	L2220F	2220	Missense	proximal	-1	no	8.517	8.535	EPSD	COSMIC	6.822	Up-regulation
Atypical_PIKK_FRAP_MTOR_ST	P42345	MTOR	P42345	MTOR	S2221	R2224K	2224	Missense	distal	3	no	8.517	7.419	EPSD	COSMIC	6.822	Down-regulation
Atypical_PIKK_FRAP_MTOR_ST	P42345	MTOR	P42345	MTOR	S2448	D2447N	2447	Missense	proximal	-1	no	6.949	6.829	EPSD	COSMIC	6.822	Down-regulation
Atypical_PIKK_FRAP_MTOR_ST	P42345	MTOR	P42345	MTOR	S2448	T2446M	2446	Missense	proximal	-2	no	6.949	6.361	EPSD	COSMIC	6.822	Loss
Atypical_PIKK_FRAP_MTOR_ST	P42345	MTOR	P42345	MTOR	S2454	D2447N	2447	Missense	distal	-7	no	7.693	7.258	PhosphoSitePlus;EPSD	COSMIC	6.822	Down-regulation
Atypical_PIKK_FRAP_MTOR_ST	P42345	MTOR	P42345	MTOR	S2454	I2457M	2457	Missense	distal	3	no	7.693	7.526	PhosphoSitePlus;EPSD	COSMIC	6.822	Down-regulation
Atypical_PIKK_FRAP_MTOR_ST	P42345	MTOR	P42345	MTOR	T2474	E2477K	2477	Missense	distal	3	no	7.756	6.126	EPSD;PhosphoSitePlus	COSMIC	6.822	Loss
Atypical_PIKK_FRAP_MTOR_ST	P42345	MTOR	P42345	MTOR	T2474	G2472E	2472	Missense	proximal	-2	no	7.756	7.116	EPSD;PhosphoSitePlus	COSMIC	6.822	Down-regulation
Atypical_PIKK_FRAP_MTOR_ST	P42345	MTOR	P42345	MTOR	T2474	P2476L	2476	Missense	proximal	2	no	7.756	7.066	EPSD;PhosphoSitePlus	COSMIC	6.822	Down-regulation
Atypical_PIKK_FRAP_MTOR_ST	P42345	MTOR	P42345	MTOR	T2474	V2475M	2475	Missense	proximal	1	no	7.756	8.546	EPSD;PhosphoSitePlus	COSMIC	6.822	Up-regulation
Atypical_PIKK_FRAP_MTOR_ST	P42345	MTOR	P42345	MTOR	S2478	E2477K	2477	Missense	proximal	-1	no	7.854	7.765	EPSD;PhosphoSitePlus	COSMIC	6.822	Down-regulation
Atypical_PIKK_FRAP_MTOR_ST	P42345	MTOR	P42345	MTOR	S2478	I2483L	2483	Missense	distal	5	no	7.854	8.837	EPSD;PhosphoSitePlus	COSMIC	6.822	Up-regulation
Atypical_PIKK_FRAP_MTOR_ST	P42345	MTOR	P42345	MTOR	S2478	G2472E	2472	Missense	distal	-6	no	7.854	7.647	EPSD;PhosphoSitePlus	COSMIC	6.822	Down-regulation
Atypical_PIKK_FRAP_MTOR_ST	P42345	MTOR	P42345	MTOR	S2478	P2476L	2476	Missense	proximal	-2	no	7.854	7.363	EPSD;PhosphoSitePlus	COSMIC	6.822	Down-regulation
Atypical_PIKK_FRAP_MTOR_ST	P42345	MTOR	P42345	MTOR	S2478	V2475M	2475	Missense	distal	-3	no	7.854	6.865	EPSD;PhosphoSitePlus	COSMIC	6.822	Down-regulation
Atypical_PIKK_FRAP_MTOR_ST	P42345	MTOR	P42345	MTOR	S2481	E2477K	2477	Missense	distal	-4	no	8.388	8.090	EPSD;PhosphoSitePlus	COSMIC	6.822	Down-regulation
Atypical_PIKK_FRAP_MTOR_ST	P42345	MTOR	P42345	MTOR	S2481	I2483L	2483	Missense	proximal	2	no	8.388	8.240	EPSD;PhosphoSitePlus	COSMIC	6.822	Down-regulation
Atypical_PIKK_FRAP_MTOR_ST	P42345	MTOR	P42345	MTOR	S2481	P2476L	2476	Missense	distal	-5	no	8.388	8.316	EPSD;PhosphoSitePlus	COSMIC	6.822	Down-regulation
Atypical_PIKK_FRAP_MTOR_ST	P42345	MTOR	P42345	MTOR	S2481	V2475M	2475	Missense	distal	-6	no	8.388	9.021	EPSD;PhosphoSitePlus	COSMIC	6.822	Up-regulation
Atypical_PIKK_FRAP_MTOR_ST	P55199	ELL	P42345	MTOR	S319	S319W	319	Missense	central	0	yes	7.877	0.000	EPSD	COSMIC	6.822	Loss
Atypical_PIKK_FRAP_MTOR_ST	P55199	ELL	P42345	MTOR	T368	T368M	368	Missense	central	0	yes	10.560	0.000	EPSD	COSMIC	6.822	Loss
Atypical_PIKK_FRAP_MTOR_ST	P55199	ELL	P42345	MTOR	T368	T368P	368	Missense	central	0	yes	10.560	0.000	EPSD	COSMIC	6.822	Loss
Atypical_PIKK_FRAP_MTOR_ST	P55199	ELL	P42345	MTOR	T368	P369L	369	Missense	proximal	1	no	10.560	4.591	EPSD	COSMIC	6.822	Loss
Atypical_PIKK_FRAP_MTOR_ST	P55199	ELL	P42345	MTOR	T368	T368I	368	Missense	central	0	yes	10.560	0.000	EPSD	COSMIC	6.822	Loss
Atypical_PIKK_FRAP_MTOR_ST	P55199	ELL	P42345	MTOR	S442	S444L	444	Missense	proximal	2	no	8.058	7.864	EPSD	COSMIC	6.822	Down-regulation
Atypical_PIKK_FRAP_MTOR_ST	P55199	ELL	P42345	MTOR	S442	G441V	441	Missense	proximal	-1	no	8.058	7.987	EPSD	COSMIC	6.822	Down-regulation
Atypical_PIKK_FRAP_MTOR_ST	P55199	ELL	P42345	MTOR	S442	P436H	436	Missense	distal	-6	no	8.058	7.339	EPSD	COSMIC	6.822	Down-regulation
Atypical_PIKK_FRAP_MTOR_ST	O75385	ULK1	P42345	MTOR	S281	S283L	283	Missense	proximal	2	no	12.562	12.367	EPSD	COSMIC	6.822	Down-regulation
Atypical_PIKK_FRAP_MTOR_ST	O75385	ULK1	P42345	MTOR	S281	P282R	282	Missense	proximal	1	no	12.562	2.728	EPSD	COSMIC	6.822	Loss
Atypical_PIKK_FRAP_MTOR_ST	O75385	ULK1	P42345	MTOR	S287	S283L	283	Missense	distal	-4	no	8.168	7.853	EPSD	COSMIC	6.822	Down-regulation
Atypical_PIKK_FRAP_MTOR_ST	O75385	ULK1	P42345	MTOR	S287	V290M	290	Missense	distal	3	no	8.168	6.745	EPSD	COSMIC	6.822	Loss
Atypical_PIKK_FRAP_MTOR_ST	O75385	ULK1	P42345	MTOR	S287	P282R	282	Missense	distal	-5	no	8.168	8.262	EPSD	COSMIC	6.822	Up-regulation
Atypical_PIKK_FRAP_MTOR_ST	O75385	ULK1	P42345	MTOR	S287	P293S	293	Missense	distal	6	no	8.168	8.198	EPSD	COSMIC	6.822	Up-regulation
Atypical_PIKK_FRAP_MTOR_ST	O75385	ULK1	P42345	MTOR	S314	L318M	318	Missense	distal	4	no	10.170	10.663	EPSD	COSMIC	6.822	Up-regulation
Atypical_PIKK_FRAP_MTOR_ST	O75385	ULK1	P42345	MTOR	S405	R400P	400	Missense	distal	-5	no	7.192	7.099	EPSD	COSMIC	6.822	Down-regulation
Atypical_PIKK_FRAP_MTOR_ST	O75385	ULK1	P42345	MTOR	S450	T452S	452	Missense	proximal	2	no	8.493	8.552	EPSD	COSMIC	6.822	Up-regulation
Atypical_PIKK_FRAP_MTOR_ST	O75385	ULK1	P42345	MTOR	S450	R443L	443	Missense	distal	-7	no	8.493	8.683	EPSD	COSMIC	6.822	Up-regulation
Atypical_PIKK_FRAP_MTOR_ST	O75385	ULK1	P42345	MTOR	S469	R463C	463	Missense	distal	-6	no	8.499	8.626	EPSD	COSMIC	6.822	Up-regulation
Atypical_PIKK_FRAP_MTOR_ST	O75385	ULK1	P42345	MTOR	S469	R463L	463	Missense	distal	-6	no	8.499	7.638	EPSD	COSMIC	6.822	Down-regulation
Atypical_PIKK_FRAP_MTOR_ST	O75385	ULK1	P42345	MTOR	S477	A484P	484	Missense	distal	7	no	12.126	12.573	EPSD	COSMIC	6.822	Up-regulation
Atypical_PIKK_FRAP_MTOR_ST	O75385	ULK1	P42345	MTOR	S477	A484T	484	Missense	distal	7	no	12.126	11.606	EPSD	COSMIC	6.822	Down-regulation
Atypical_PIKK_FRAP_MTOR_ST	O75385	ULK1	P42345	MTOR	S479	A484P	484	Missense	distal	5	no	10.447	10.132	EPSD	COSMIC	6.822	Down-regulation
Atypical_PIKK_FRAP_MTOR_ST	O75385	ULK1	P42345	MTOR	S479	A484T	484	Missense	distal	5	no	10.447	9.621	EPSD	COSMIC	6.822	Down-regulation
Atypical_PIKK_FRAP_MTOR_ST	O75385	ULK1	P42345	MTOR	T510	R514Q	514	Missense	distal	4	no	8.039	8.170	EPSD	COSMIC	6.822	Up-regulation
Atypical_PIKK_FRAP_MTOR_ST	O75385	ULK1	P42345	MTOR	T520	R514Q	514	Missense	distal	-6	no	10.741	10.476	EPSD	COSMIC	6.822	Down-regulation
Atypical_PIKK_FRAP_MTOR_ST	O75385	ULK1	P42345	MTOR	T520	G519R	519	Missense	proximal	-1	no	10.741	10.586	EPSD	COSMIC	6.822	Down-regulation
Atypical_PIKK_FRAP_MTOR_ST	O75385	ULK1	P42345	MTOR	S522	G519R	519	Missense	distal	-3	no	12.786	12.760	EPSD	COSMIC	6.822	Down-regulation
Atypical_PIKK_FRAP_MTOR_ST	O75385	ULK1	P42345	MTOR	S522	R529Q	529	Missense	distal	7	no	12.786	12.386	EPSD	COSMIC;CCLE	6.822	Down-regulation
Atypical_PIKK_FRAP_MTOR_ST	O75385	ULK1	P42345	MTOR	S544	P541H	541	Missense	distal	-3	no	7.935	7.966	EPSD	COSMIC	6.822	Up-regulation
Atypical_PIKK_FRAP_MTOR_ST	O75385	ULK1	P42345	MTOR	S583	P590S	590	Missense	distal	7	no	9.447	9.426	EPSD	COSMIC	6.822	Down-regulation
Atypical_PIKK_FRAP_MTOR_ST	O75385	ULK1	P42345	MTOR	S623	P619L	619	Missense	distal	-4	no	10.840	10.654	EPSD	COSMIC	6.822	Down-regulation
Atypical_PIKK_FRAP_MTOR_ST	O75385	ULK1	P42345	MTOR	S623	T625I	625	Missense	proximal	2	no	10.840	10.851	EPSD	COSMIC	6.822	Up-regulation
Atypical_PIKK_FRAP_MTOR_ST	O75385	ULK1	P42345	MTOR	T636	P634L	634	Missense	proximal	-2	no	14.602	14.112	EPSD	COSMIC;GDSC	6.822	Down-regulation
Atypical_PIKK_FRAP_MTOR_ST	O75385	ULK1	P42345	MTOR	S638	P634L	634	Missense	distal	-4	no	7.101	6.915	EPSD;PhosphoSitePlus	COSMIC;GDSC	6.822	Down-regulation
Atypical_PIKK_FRAP_MTOR_ST	O75385	ULK1	P42345	MTOR	T654	T660M	660	Missense	distal	6	no	9.678	9.208	EPSD	COSMIC	6.822	Down-regulation
Atypical_PIKK_FRAP_MTOR_ST	O75385	ULK1	P42345	MTOR	T654	R659W	659	Missense	distal	5	no	9.678	8.695	EPSD	COSMIC	6.822	Down-regulation
Atypical_PIKK_FRAP_MTOR_ST	O75385	ULK1	P42345	MTOR	T654	V652G	652	Missense	proximal	-2	no	9.678	10.326	EPSD	COSMIC	6.822	Up-regulation
Atypical_PIKK_FRAP_MTOR_ST	O75385	ULK1	P42345	MTOR	T654	T654M	654	Missense	central	0	yes	9.678	0.000	EPSD	COSMIC	6.822	Loss
Atypical_PIKK_FRAP_MTOR_ST	O75385	ULK1	P42345	MTOR	S973	R966Q	966	Missense	distal	-7	no	8.221	8.144	EPSD	COSMIC	6.822	Down-regulation
Atypical_PIKK_FRAP_MTOR_ST	O75385	ULK1	P42345	MTOR	S973	S973G	973	Missense	central	0	yes	8.221	0.000	EPSD	COSMIC	6.822	Loss
Atypical_PIKK_FRAP_MTOR_ST	O75385	ULK1	P42345	MTOR	S1042	R1039W	1039	Missense	distal	-3	no	6.982	6.767	EPSD	COSMIC	6.822	Loss
Atypical_PIKK_FRAP_MTOR_ST	O75385	ULK1	P42345	MTOR	S1042	L1045V	1045	Missense	distal	3	no	6.982	8.295	EPSD	COSMIC	6.822	Up-regulation
Atypical_PIKK_FRAP_MTOR_ST	Q9H8M2	BRD9	P42345	MTOR	T139	P140L	140	Missense	proximal	1	no	15.435	9.466	EPSD	COSMIC	6.822	Down-regulation
Atypical_PIKK_FRAP_MTOR_ST	Q9H8M2	BRD9	P42345	MTOR	T139	E135K	135	Missense	distal	-4	no	15.435	15.137	EPSD	COSMIC	6.822	Down-regulation
Atypical_PIKK_FRAP_MTOR_ST	Q9H8M2	BRD9	P42345	MTOR	T139	L145P	145	Missense	distal	6	no	15.435	16.595	EPSD	COSMIC	6.822	Up-regulation
Atypical_PIKK_FRAP_MTOR_ST	Q9H8M2	BRD9	P42345	MTOR	T139	E137G	137	Missense	proximal	-2	no	15.435	16.075	EPSD	COSMIC	6.822	Up-regulation
Atypical_PIKK_FRAP_MTOR_ST	Q9H8M2	BRD9	P42345	MTOR	S357	S358L	358	Missense	proximal	1	no	5.478	8.032	EPSD	COSMIC	6.822	Gain
Atypical_PIKK_FRAP_MTOR_ST	Q9H8M2	BRD9	P42345	MTOR	S571	L564V	564	Missense	distal	-7	no	6.956	6.798	EPSD	COSMIC	6.822	Loss
Atypical_PIKK_FRAP_MTOR_ST	Q9H8M2	BRD9	P42345	MTOR	S571	R569S	569	Missense	proximal	-2	no	6.956	7.084	EPSD	COSMIC	6.822	Up-regulation
Atypical_PIKK_FRAP_MTOR_ST	Q8TB45	DEPTOR	P42345	MTOR	S235	E233K	233	Missense	proximal	-2	no	13.932	13.970	EPSD	COSMIC	6.822	Up-regulation
Atypical_PIKK_FRAP_MTOR_ST	Q8TB45	DEPTOR	P42345	MTOR	S244	P245A	245	Missense	proximal	1	no	10.341	1.458	EPSD	COSMIC	6.822	Loss
Atypical_PIKK_FRAP_MTOR_ST	Q8TB45	DEPTOR	P42345	MTOR	S244	L248M	248	Missense	distal	4	no	10.341	10.834	EPSD	COSMIC;GDSC;CCLE	6.822	Up-regulation
Atypical_PIKK_FRAP_MTOR_ST	Q8TB45	DEPTOR	P42345	MTOR	S244	Q251R	251	Missense	distal	7	no	10.341	10.741	EPSD	COSMIC	6.822	Up-regulation
Atypical_PIKK_FRAP_MTOR_ST	Q8TB45	DEPTOR	P42345	MTOR	S260	S260I	260	Missense	central	0	yes	7.170	0.000	EPSD	COSMIC	6.822	Loss
Atypical_PIKK_FRAP_MTOR_ST	Q8TB45	DEPTOR	P42345	MTOR	S260	R256W	256	Missense	distal	-4	no	7.170	7.280	EPSD	COSMIC	6.822	Up-regulation
Atypical_PIKK_FRAP_MTOR_ST	Q8TB45	DEPTOR	P42345	MTOR	S265	S260I	260	Missense	distal	-5	no	12.264	12.329	EPSD;PhosphoSitePlus	COSMIC	6.822	Up-regulation
Atypical_PIKK_FRAP_MTOR_ST	Q8TB45	DEPTOR	P42345	MTOR	S280	S282G	282	Missense	proximal	2	no	7.422	7.242	EPSD	COSMIC	6.822	Down-regulation
Atypical_PIKK_FRAP_MTOR_ST	Q8TB45	DEPTOR	P42345	MTOR	S280	C284Y	284	Missense	distal	4	no	7.422	7.529	EPSD	COSMIC	6.822	Up-regulation
Atypical_PIKK_FRAP_MTOR_ST	Q8TB45	DEPTOR	P42345	MTOR	S280	S286I	286	Missense	distal	6	no	7.422	6.558	EPSD	COSMIC	6.822	Loss
Atypical_PIKK_FRAP_MTOR_ST	Q8TB45	DEPTOR	P42345	MTOR	S293	P294L	294	Missense	proximal	1	no	8.165	2.196	EPSD;PhosphoSitePlus	COSMIC	6.822	Loss
Atypical_PIKK_FRAP_MTOR_ST	Q8TB45	DEPTOR	P42345	MTOR	S293	S298N	298	Missense	distal	5	no	8.165	9.647	EPSD;PhosphoSitePlus	COSMIC	6.822	Up-regulation
Atypical_PIKK_FRAP_MTOR_ST	Q8TB45	DEPTOR	P42345	MTOR	S293	S286I	286	Missense	distal	-7	no	8.165	7.159	EPSD;PhosphoSitePlus	COSMIC	6.822	Down-regulation
Atypical_PIKK_FRAP_MTOR_ST	Q8TB45	DEPTOR	P42345	MTOR	T295	P294L	294	Missense	proximal	-1	no	9.860	9.726	PhosphoSitePlus;EPSD	COSMIC	6.822	Down-regulation
Atypical_PIKK_FRAP_MTOR_ST	Q8TB45	DEPTOR	P42345	MTOR	T295	S298N	298	Missense	distal	3	no	9.860	9.316	PhosphoSitePlus;EPSD	COSMIC	6.822	Down-regulation
Atypical_PIKK_FRAP_MTOR_ST	Q8TB45	DEPTOR	P42345	MTOR	S299	P306H	306	Missense	distal	7	no	10.357	10.972	EPSD;PhosphoSitePlus	COSMIC	6.822	Up-regulation
Atypical_PIKK_FRAP_MTOR_ST	Q8TB45	DEPTOR	P42345	MTOR	S299	P294L	294	Missense	distal	-5	no	10.357	10.285	EPSD;PhosphoSitePlus	COSMIC	6.822	Down-regulation
Atypical_PIKK_FRAP_MTOR_ST	Q8TB45	DEPTOR	P42345	MTOR	S299	S298N	298	Missense	proximal	-1	no	10.357	10.176	EPSD;PhosphoSitePlus	COSMIC	6.822	Down-regulation
Atypical_PIKK_FRAP_MTOR_ST	Q8TB45	DEPTOR	P42345	MTOR	S299	P306T	306	Missense	distal	7	no	10.357	9.390	EPSD;PhosphoSitePlus	COSMIC	6.822	Down-regulation
Atypical_PIKK_FRAP_MTOR_ST	Q8TB45	DEPTOR	P42345	MTOR	T321	T321I	321	Missense	central	0	yes	12.533	0.000	EPSD	COSMIC	6.822	Loss
Atypical_PIKK_FRAP_MTOR_ST	Q8TB45	DEPTOR	P42345	MTOR	T321	P322S	322	Missense	proximal	1	no	12.533	4.009	EPSD	COSMIC	6.822	Loss
Atypical_PIKK_FRAP_MTOR_ST	Q8TB45	DEPTOR	P42345	MTOR	T321	E318K	318	Missense	distal	-3	no	12.533	12.538	EPSD	COSMIC	6.822	Up-regulation
Atypical_PIKK_FRAP_MTOR_ST	Q8TB45	DEPTOR	P42345	MTOR	T321	G323E	323	Missense	proximal	2	no	12.533	13.551	EPSD	COSMIC	6.822	Up-regulation
Atypical_PIKK_FRAP_MTOR_ST	Q8TB45	DEPTOR	P42345	MTOR	T321	G323V	323	Missense	proximal	2	no	12.533	12.697	EPSD	COSMIC	6.822	Up-regulation
Atypical_PIKK_FRAP_MTOR_ST	Q8TB45	DEPTOR	P42345	MTOR	T394	V388M	388	Missense	distal	-6	no	7.371	8.004	EPSD	COSMIC;GDSC;CCLE	6.822	Up-regulation
Atypical_PIKK_FRAP_MTOR_ST	Q8TB45	DEPTOR	P42345	MTOR	T394	S389N	389	Missense	distal	-5	no	7.371	7.282	EPSD	COSMIC	6.822	Down-regulation
Atypical_PIKK_FRAP_MTOR_ST	Q8TB45	DEPTOR	P42345	MTOR	T394	P396Q	396	Missense	proximal	2	no	7.371	5.152	EPSD	COSMIC	6.822	Loss
Atypical_PIKK_FRAP_MTOR_ST	Q8TB45	DEPTOR	P42345	MTOR	T394	L391V	391	Missense	distal	-3	no	7.371	7.092	EPSD	COSMIC	6.822	Down-regulation
Atypical_PIKK_FRAP_MTOR_ST	P23443	RPS6KB1	P42345	MTOR	T390	P391S	391	Missense	proximal	1	no	8.855	0.331	EPSD	COSMIC	6.822	Loss
Atypical_PIKK_FRAP_MTOR_ST	P23443	RPS6KB1	P42345	MTOR	T390	R388G	388	Missense	proximal	-2	no	8.855	9.713	EPSD	COSMIC	6.822	Up-regulation
Atypical_PIKK_FRAP_MTOR_ST	P23443	RPS6KB1	P42345	MTOR	S394	P391S	391	Missense	distal	-3	no	7.418	7.851	PhosphoSitePlus;EPSD	COSMIC	6.822	Up-regulation
Atypical_PIKK_FRAP_MTOR_ST	P23443	RPS6KB1	P42345	MTOR	S394	S401N	401	Missense	distal	7	no	7.418	8.017	PhosphoSitePlus;EPSD	COSMIC;CCLE	6.822	Up-regulation
Atypical_PIKK_FRAP_MTOR_ST	P23443	RPS6KB1	P42345	MTOR	S394	S398T	398	Missense	distal	4	no	7.418	7.486	PhosphoSitePlus;EPSD	COSMIC	6.822	Up-regulation
Atypical_PIKK_FRAP_MTOR_ST	P23443	RPS6KB1	P42345	MTOR	S394	R388G	388	Missense	distal	-6	no	7.418	7.433	PhosphoSitePlus;EPSD	COSMIC	6.822	Up-regulation
Atypical_PIKK_FRAP_MTOR_ST	P23443	RPS6KB1	P42345	MTOR	T399	A404V	404	Missense	distal	5	no	6.317	7.011	EPSD	COSMIC	6.822	Gain
Atypical_PIKK_FRAP_MTOR_ST	P23443	RPS6KB1	P42345	MTOR	T412	T412A	412	Missense	central	0	yes	10.409	0.000	EPSD;PhosphoSitePlus	COSMIC	6.822	Loss
Atypical_PIKK_FRAP_MTOR_ST	P23443	RPS6KB1	P42345	MTOR	T412	V414E	414	Missense	proximal	2	no	10.409	11.264	EPSD;PhosphoSitePlus	COSMIC	6.822	Up-regulation
Atypical_PIKK_FRAP_MTOR_ST	P23443	RPS6KB1	P42345	MTOR	S421	V414E	414	Missense	distal	-7	no	8.981	9.304	EPSD	COSMIC	6.822	Up-regulation
Atypical_PIKK_FRAP_MTOR_ST	P23443	RPS6KB1	P42345	MTOR	S427	I432T	432	Missense	distal	5	no	9.371	8.471	EPSD	COSMIC	6.822	Down-regulation
Atypical_PIKK_FRAP_MTOR_ST	P23443	RPS6KB1	P42345	MTOR	S427	E429Q	429	Missense	proximal	2	no	9.371	6.809	EPSD	COSMIC	6.822	Loss
Atypical_PIKK_FRAP_MTOR_ST	P23443	RPS6KB1	P42345	MTOR	S434	I432T	432	Missense	proximal	-2	no	11.217	11.721	EPSD;PhosphoSitePlus	COSMIC	6.822	Up-regulation
Atypical_PIKK_FRAP_MTOR_ST	P23443	RPS6KB1	P42345	MTOR	S434	G440A	440	Missense	distal	6	no	11.217	10.637	EPSD;PhosphoSitePlus	COSMIC	6.822	Down-regulation
Atypical_PIKK_FRAP_MTOR_ST	P23443	RPS6KB1	P42345	MTOR	S434	R436Q	436	Missense	proximal	2	no	11.217	11.205	EPSD;PhosphoSitePlus	COSMIC	6.822	Down-regulation
Atypical_PIKK_FRAP_MTOR_ST	P23443	RPS6KB1	P42345	MTOR	S434	E429Q	429	Missense	distal	-5	no	11.217	11.580	EPSD;PhosphoSitePlus	COSMIC	6.822	Up-regulation
Atypical_PIKK_FRAP_MTOR_ST	P23443	RPS6KB1	P42345	MTOR	S441	G440A	440	Missense	proximal	-1	no	9.365	9.366	EPSD	COSMIC	6.822	Up-regulation
Atypical_PIKK_FRAP_MTOR_ST	P23443	RPS6KB1	P42345	MTOR	S441	P445L	445	Missense	distal	4	no	9.365	8.981	EPSD	COSMIC	6.822	Down-regulation
Atypical_PIKK_FRAP_MTOR_ST	P23443	RPS6KB1	P42345	MTOR	S441	R436Q	436	Missense	distal	-5	no	9.365	9.280	EPSD	COSMIC	6.822	Down-regulation
Atypical_PIKK_FRAP_MTOR_ST	P23443	RPS6KB1	P42345	MTOR	T444	G440A	440	Missense	distal	-4	no	9.326	8.930	EPSD	COSMIC	6.822	Down-regulation
Atypical_PIKK_FRAP_MTOR_ST	P23443	RPS6KB1	P42345	MTOR	T444	P445L	445	Missense	proximal	1	no	9.326	3.357	EPSD	COSMIC	6.822	Loss
Atypical_PIKK_FRAP_MTOR_ST	P23443	RPS6KB1	P42345	MTOR	S447	G440A	440	Missense	distal	-7	no	9.793	9.515	EPSD	COSMIC	6.822	Down-regulation
Atypical_PIKK_FRAP_MTOR_ST	P23443	RPS6KB1	P42345	MTOR	S447	P445L	445	Missense	proximal	-2	no	9.793	9.302	EPSD	COSMIC	6.822	Down-regulation
Atypical_PIKK_FRAP_MTOR_ST	P23443	RPS6KB1	P42345	MTOR	S447	G454W	454	Missense	distal	7	no	9.793	9.815	EPSD	COSMIC	6.822	Up-regulation
Atypical_PIKK_FRAP_MTOR_ST	P23443	RPS6KB1	P42345	MTOR	S452	P445L	445	Missense	distal	-7	no	7.565	7.432	EPSD	COSMIC	6.822	Down-regulation
Atypical_PIKK_FRAP_MTOR_ST	P23443	RPS6KB1	P42345	MTOR	S452	G454W	454	Missense	proximal	2	no	7.565	6.923	EPSD	COSMIC	6.822	Down-regulation
Atypical_PIKK_FRAP_MTOR_ST	P23443	RPS6KB1	P42345	MTOR	S462	S464N	464	Missense	proximal	2	no	7.188	5.787	EPSD	COSMIC	6.822	Loss
Atypical_PIKK_FRAP_MTOR_ST	P23443	RPS6KB1	P42345	MTOR	S462	S462L	462	Missense	central	0	yes	7.188	0.000	EPSD	COSMIC	6.822	Loss
Atypical_PIKK_FRAP_MTOR_ST	P23443	RPS6KB1	P42345	MTOR	S462	P468T	468	Missense	distal	6	no	7.188	6.304	EPSD	COSMIC	6.822	Loss
Atypical_PIKK_FRAP_MTOR_ST	P23443	RPS6KB1	P42345	MTOR	T470	S464N	464	Missense	distal	-6	no	9.941	9.254	EPSD	COSMIC	6.822	Down-regulation
Atypical_PIKK_FRAP_MTOR_ST	P23443	RPS6KB1	P42345	MTOR	T470	P468T	468	Missense	proximal	-2	no	9.941	9.649	EPSD	COSMIC	6.822	Down-regulation
Atypical_PIKK_FRAP_MTOR_ST	P03372	ESR1	P42345	MTOR	S104	F97L	97	Missense	distal	-7	no	9.917	9.573	EPSD;PhosphoSitePlus	COSMIC	6.822	Down-regulation
Atypical_PIKK_FRAP_MTOR_ST	P03372	ESR1	P42345	MTOR	S104	M109T	109	Missense	distal	5	no	9.917	9.653	EPSD;PhosphoSitePlus	COSMIC	6.822	Down-regulation
Atypical_PIKK_FRAP_MTOR_ST	P03372	ESR1	P42345	MTOR	S106	P113L	113	Missense	distal	7	no	8.413	9.369	PhosphoSitePlus;EPSD	COSMIC	6.822	Up-regulation
Atypical_PIKK_FRAP_MTOR_ST	P03372	ESR1	P42345	MTOR	S106	P113Q	113	Missense	distal	7	no	8.413	8.785	PhosphoSitePlus;EPSD	COSMIC	6.822	Up-regulation
Atypical_PIKK_FRAP_MTOR_ST	P03372	ESR1	P42345	MTOR	S106	H112L	112	Missense	distal	6	no	8.413	8.729	PhosphoSitePlus;EPSD	COSMIC	6.822	Up-regulation
Atypical_PIKK_FRAP_MTOR_ST	P03372	ESR1	P42345	MTOR	S106	M109T	109	Missense	distal	3	no	8.413	10.385	PhosphoSitePlus;EPSD	COSMIC	6.822	Up-regulation
Atypical_PIKK_FRAP_MTOR_ST	P03372	ESR1	P42345	MTOR	S341	S338G	338	Missense	distal	-3	no	10.280	10.652	EPSD	COSMIC	6.822	Up-regulation
Atypical_PIKK_FRAP_MTOR_ST	P03372	ESR1	P42345	MTOR	S341	S338R	338	Missense	distal	-3	no	10.280	10.626	EPSD	COSMIC	6.822	Up-regulation
Atypical_PIKK_FRAP_MTOR_ST	P03372	ESR1	P42345	MTOR	S341	T347I	347	Missense	distal	6	no	10.280	10.330	EPSD	COSMIC	6.822	Up-regulation
Atypical_PIKK_FRAP_MTOR_ST	P03372	ESR1	P42345	MTOR	S341	M343L	343	Missense	proximal	2	no	10.280	11.520	EPSD	COSMIC	6.822	Up-regulation
Atypical_PIKK_FRAP_MTOR_ST	P03372	ESR1	P42345	MTOR	S559	G557R	557	Missense	proximal	-2	no	8.025	7.168	EPSD	COSMIC	6.822	Down-regulation
Atypical_PIKK_FRAP_MTOR_ST	P03372	ESR1	P42345	MTOR	S559	D564Y	564	Missense	distal	5	no	8.025	8.855	EPSD	COSMIC	6.822	Up-regulation
Atypical_PIKK_FRAP_MTOR_ST	P03372	ESR1	P42345	MTOR	S559	V560M	560	Missense	proximal	1	no	8.025	8.815	EPSD	COSMIC	6.822	Up-regulation
Atypical_PIKK_FRAP_MTOR_ST	P03372	ESR1	P42345	MTOR	S559	D564N	564	Missense	distal	5	no	8.025	9.472	EPSD	COSMIC	6.822	Up-regulation
Atypical_PIKK_FRAP_MTOR_ST	Q641Q2	WASHC2A	P42345	MTOR	T6	Q9R	9	Missense	distal	3	no	5.784	7.050	EPSD	COSMIC	6.822	Gain
Atypical_PIKK_FRAP_MTOR_ST	Q641Q2	WASHC2A	P42345	MTOR	S441	G444D	444	Missense	distal	3	no	7.224	5.482	EPSD	COSMIC	6.822	Loss
Atypical_PIKK_FRAP_MTOR_ST	Q641Q2	WASHC2A	P42345	MTOR	S464	A465V	465	Missense	proximal	1	no	6.360	8.522	EPSD	COSMIC	6.822	Gain
Atypical_PIKK_FRAP_MTOR_ST	Q641Q2	WASHC2A	P42345	MTOR	S1091	G1088V	1088	Missense	distal	-3	no	6.966	6.730	EPSD	COSMIC	6.822	Loss
Atypical_PIKK_FRAP_MTOR_ST	Q641Q2	WASHC2A	P42345	MTOR	S1091	E1089D	1089	Missense	proximal	-2	no	6.966	6.552	EPSD	COSMIC	6.822	Loss
Atypical_PIKK_FRAP_MTOR_ST	Q641Q2	WASHC2A	P42345	MTOR	S1169	G1176V	1176	Missense	distal	7	no	6.840	6.969	EPSD	COSMIC	6.822	Up-regulation
Atypical_PIKK_FRAP_MTOR_ST	Q641Q2	WASHC2A	P42345	MTOR	S1179	G1176V	1176	Missense	distal	-3	no	8.562	8.326	EPSD	COSMIC	6.822	Down-regulation
Atypical_PIKK_FRAP_MTOR_ST	Q641Q2	WASHC2A	P42345	MTOR	S1179	S1180N	1180	Missense	proximal	1	no	8.562	9.413	EPSD	COSMIC	6.822	Up-regulation
Atypical_PIKK_FRAP_MTOR_ST	Q641Q2	WASHC2A	P42345	MTOR	S1179	E1177D	1177	Missense	proximal	-2	no	8.562	8.148	EPSD	COSMIC	6.822	Down-regulation
Atypical_PIKK_FRAP_MTOR_ST	Q641Q2	WASHC2A	P42345	MTOR	S1328	K1326M	1326	Missense	proximal	-2	no	11.913	11.261	EPSD	COSMIC	6.822	Down-regulation
Atypical_PIKK_FRAP_MTOR_ST	Q641Q2	WASHC2A	P42345	MTOR	S1328	D1333E	1333	Missense	distal	5	no	11.913	11.495	EPSD	COSMIC	6.822	Down-regulation
Atypical_PIKK_FRAP_MTOR_ST	Q641Q2	WASHC2A	P42345	MTOR	S1328	L1335P	1335	Missense	distal	7	no	11.913	10.957	EPSD	COSMIC	6.822	Down-regulation
Atypical_PIKK_FRAP_MTOR_ST	Q641Q2	WASHC2A	P42345	MTOR	S1328	R1322T	1322	Missense	distal	-6	no	11.913	11.747	EPSD	COSMIC	6.822	Down-regulation
Atypical_PIKK_FRAP_MTOR_ST	Q641Q2	WASHC2A	P42345	MTOR	S1328	D1333A	1333	Missense	distal	5	no	11.913	12.307	EPSD	COSMIC	6.822	Up-regulation
Atypical_PIKK_FRAP_MTOR_ST	Q641Q2	WASHC2A	P42345	MTOR	S1328	D1333N	1333	Missense	distal	5	no	11.913	13.360	EPSD	COSMIC	6.822	Up-regulation
Atypical_PIKK_FRAP_MTOR_ST	Q9P2Y5	UVRAG	P42345	MTOR	T108	S109P	109	Missense	proximal	1	no	4.323	12.847	EPSD	COSMIC	6.822	Gain
Atypical_PIKK_FRAP_MTOR_ST	Q9P2Y5	UVRAG	P42345	MTOR	S571	G570E	570	Missense	proximal	-1	no	7.978	7.952	EPSD;PhosphoSitePlus	COSMIC	6.822	Down-regulation
Atypical_PIKK_FRAP_MTOR_ST	Q9P2Y5	UVRAG	P42345	MTOR	S571	E566K	566	Missense	distal	-5	no	7.978	8.270	EPSD;PhosphoSitePlus	COSMIC	6.822	Up-regulation
Atypical_PIKK_FRAP_MTOR_ST	P19484	TFEB	P42345	MTOR	T50	P49L	49	Missense	proximal	-1	no	8.817	8.683	EPSD	COSMIC	6.822	Down-regulation
Atypical_PIKK_FRAP_MTOR_ST	P19484	TFEB	P42345	MTOR	S109	H107N	107	Missense	proximal	-2	no	8.510	8.277	EPSD	COSMIC	6.822	Down-regulation
Atypical_PIKK_FRAP_MTOR_ST	P19484	TFEB	P42345	MTOR	S114	H107N	107	Missense	distal	-7	no	8.733	9.651	EPSD	COSMIC	6.822	Up-regulation
Atypical_PIKK_FRAP_MTOR_ST	P19484	TFEB	P42345	MTOR	S122	A127V	127	Missense	distal	5	no	9.332	10.026	PhosphoSitePlus;EPSD	COSMIC	6.822	Up-regulation
Atypical_PIKK_FRAP_MTOR_ST	P19484	TFEB	P42345	MTOR	S142	M146I	146	Missense	distal	4	no	11.712	11.423	EPSD	COSMIC	6.822	Down-regulation
Atypical_PIKK_FRAP_MTOR_ST	P19484	TFEB	P42345	MTOR	S142	N137H	137	Missense	distal	-5	no	11.712	11.947	EPSD	COSMIC	6.822	Up-regulation
Atypical_PIKK_FRAP_MTOR_ST	P19484	TFEB	P42345	MTOR	S142	A135D	135	Missense	distal	-7	no	11.712	12.797	EPSD	COSMIC	6.822	Up-regulation
Atypical_PIKK_FRAP_MTOR_ST	P19484	TFEB	P42345	MTOR	S195	P198L	198	Missense	distal	3	no	7.056	4.802	EPSD	COSMIC	6.822	Loss
Atypical_PIKK_FRAP_MTOR_ST	P19484	TFEB	P42345	MTOR	S195	L191P	191	Missense	distal	-4	no	7.056	7.242	EPSD	COSMIC	6.822	Up-regulation
Atypical_PIKK_FRAP_MTOR_ST	P19484	TFEB	P42345	MTOR	S211	L204M	204	Missense	distal	-7	no	8.216	8.198	EPSD;PhosphoSitePlus	COSMIC	6.822	Down-regulation
Atypical_PIKK_FRAP_MTOR_ST	P19484	TFEB	P42345	MTOR	S211	S210Y	210	Missense	proximal	-1	no	8.216	8.043	EPSD;PhosphoSitePlus	COSMIC	6.822	Down-regulation
Atypical_PIKK_FRAP_MTOR_ST	P19484	TFEB	P42345	MTOR	S332	N337K	337	Missense	distal	5	no	8.896	7.086	EPSD	COSMIC	6.822	Down-regulation
Atypical_PIKK_FRAP_MTOR_ST	P19484	TFEB	P42345	MTOR	S332	N337D	337	Missense	distal	5	no	8.896	7.449	EPSD	COSMIC	6.822	Down-regulation
Atypical_PIKK_FRAP_MTOR_ST	P19484	TFEB	P42345	MTOR	S332	P333L	333	Missense	proximal	1	no	8.896	2.927	EPSD	COSMIC	6.822	Loss
Atypical_PIKK_FRAP_MTOR_ST	P19484	TFEB	P42345	MTOR	S332	P329S	329	Missense	distal	-3	no	8.896	9.328	EPSD	COSMIC	6.822	Up-regulation
Atypical_PIKK_FRAP_MTOR_ST	P19484	TFEB	P42345	MTOR	S423	A418T	418	Missense	distal	-5	no	8.283	8.262	EPSD	COSMIC	6.822	Down-regulation
Atypical_PIKK_FRAP_MTOR_ST	P19484	TFEB	P42345	MTOR	S423	P419L	419	Missense	distal	-4	no	8.283	8.097	EPSD	COSMIC	6.822	Down-regulation
Atypical_PIKK_FRAP_MTOR_ST	P19484	TFEB	P42345	MTOR	S423	P424L	424	Missense	proximal	1	no	8.283	2.313	EPSD	COSMIC	6.822	Loss
Atypical_PIKK_FRAP_MTOR_ST	P19484	TFEB	P42345	MTOR	S455	A458S	458	Missense	distal	3	no	14.349	13.294	EPSD	COSMIC	6.822	Down-regulation
Atypical_PIKK_FRAP_MTOR_ST	P19484	TFEB	P42345	MTOR	S455	S462N	462	Missense	distal	7	no	14.349	14.948	EPSD	COSMIC	6.822	Up-regulation
Atypical_PIKK_FRAP_MTOR_ST	P19484	TFEB	P42345	MTOR	S455	D448N	448	Missense	distal	-7	no	14.349	13.914	EPSD	COSMIC	6.822	Down-regulation
Atypical_PIKK_FRAP_MTOR_ST	P19484	TFEB	P42345	MTOR	S462	R464C	464	Missense	proximal	2	no	10.081	10.247	EPSD	COSMIC	6.822	Up-regulation
Atypical_PIKK_FRAP_MTOR_ST	P19484	TFEB	P42345	MTOR	S462	A458S	458	Missense	distal	-4	no	10.081	11.044	EPSD	COSMIC	6.822	Up-regulation
Atypical_PIKK_FRAP_MTOR_ST	P19484	TFEB	P42345	MTOR	S462	S462N	462	Missense	central	0	yes	10.081	0.000	EPSD	COSMIC	6.822	Loss
Atypical_PIKK_FRAP_MTOR_ST	P19484	TFEB	P42345	MTOR	S463	R464C	464	Missense	proximal	1	no	5.699	7.138	EPSD	COSMIC	6.822	Gain
Atypical_PIKK_FRAP_MTOR_ST	P19484	TFEB	P42345	MTOR	S467	R464C	464	Missense	distal	-3	no	10.630	9.918	EPSD	COSMIC	6.822	Down-regulation
Atypical_PIKK_FRAP_MTOR_ST	P19484	TFEB	P42345	MTOR	S467	S462N	462	Missense	distal	-5	no	10.630	10.541	EPSD	COSMIC	6.822	Down-regulation
Atypical_PIKK_FRAP_MTOR_ST	P19484	TFEB	P42345	MTOR	S469	R464C	464	Missense	distal	-5	no	17.972	18.096	EPSD	COSMIC	6.822	Up-regulation
Atypical_PIKK_FRAP_MTOR_ST	P19484	TFEB	P42345	MTOR	S469	S462N	462	Missense	distal	-7	no	17.972	17.781	EPSD	COSMIC	6.822	Down-regulation
Atypical_PIKK_FRAP_MTOR_ST	Q9H4L4	SENP3	P42345	MTOR	S26	R29Q	29	Missense	distal	3	no	9.652	8.386	PhosphoSitePlus;EPSD	COSMIC	6.822	Down-regulation
Atypical_PIKK_FRAP_MTOR_ST	Q9H4L4	SENP3	P42345	MTOR	S26	R31C	31	Missense	distal	5	no	9.652	9.436	PhosphoSitePlus;EPSD	COSMIC	6.822	Down-regulation
Atypical_PIKK_FRAP_MTOR_ST	Q9H4L4	SENP3	P42345	MTOR	S188	P192L	192	Missense	distal	4	no	11.827	11.443	EPSD	COSMIC;GDSC	6.822	Down-regulation
Atypical_PIKK_FRAP_MTOR_ST	Q9H4L4	SENP3	P42345	MTOR	S188	R190W	190	Missense	proximal	2	no	11.827	12.719	EPSD	COSMIC	6.822	Up-regulation
Atypical_PIKK_FRAP_MTOR_ST	Q9H4L4	SENP3	P42345	MTOR	S212	V209M	209	Missense	distal	-3	no	7.513	6.524	EPSD	COSMIC;GDSC;CCLE	6.822	Loss
Atypical_PIKK_FRAP_MTOR_ST	Q9H4L4	SENP3	P42345	MTOR	T229	T229I	229	Missense	central	0	yes	9.516	0.000	EPSD	COSMIC	6.822	Loss
Atypical_PIKK_FRAP_MTOR_ST	Q9H4L4	SENP3	P42345	MTOR	T229	R227S	227	Missense	proximal	-2	no	9.516	9.644	EPSD	COSMIC;GDSC;CCLE	6.822	Up-regulation
Atypical_PIKK_FRAP_MTOR_ST	Q9H4L4	SENP3	P42345	MTOR	S232	T229I	229	Missense	distal	-3	no	11.290	12.165	EPSD	COSMIC	6.822	Up-regulation
Atypical_PIKK_FRAP_MTOR_ST	Q9H4L4	SENP3	P42345	MTOR	S232	R227S	227	Missense	distal	-5	no	11.290	11.148	EPSD	COSMIC;GDSC;CCLE	6.822	Down-regulation
Atypical_PIKK_FRAP_MTOR_ST	Q9H4L4	SENP3	P42345	MTOR	S352	P354L	354	Missense	proximal	2	no	8.272	7.582	EPSD	COSMIC	6.822	Down-regulation
Atypical_PIKK_FRAP_MTOR_ST	Q9H4L4	SENP3	P42345	MTOR	T353	P354L	354	Missense	proximal	1	no	10.742	4.773	EPSD	COSMIC	6.822	Loss
Atypical_PIKK_FRAP_MTOR_ST	Q8IYB3	SRRM1	P42345	MTOR	S171	E164Q	164	Missense	distal	-7	no	9.699	9.267	EPSD	COSMIC	6.822	Down-regulation
Atypical_PIKK_FRAP_MTOR_ST	Q8IYB3	SRRM1	P42345	MTOR	S209	R202H	202	Missense	distal	-7	no	10.325	9.976	EPSD	COSMIC	6.822	Down-regulation
Atypical_PIKK_FRAP_MTOR_ST	Q8IYB3	SRRM1	P42345	MTOR	S209	R208Q	208	Missense	proximal	-1	no	10.325	10.343	EPSD	COSMIC;CCLE	6.822	Up-regulation
Atypical_PIKK_FRAP_MTOR_ST	Q8IYB3	SRRM1	P42345	MTOR	S209	P210S	210	Missense	proximal	1	no	10.325	1.801	EPSD	COSMIC	6.822	Loss
Atypical_PIKK_FRAP_MTOR_ST	Q8IYB3	SRRM1	P42345	MTOR	S209	P210L	210	Missense	proximal	1	no	10.325	4.355	EPSD	COSMIC	6.822	Loss
Atypical_PIKK_FRAP_MTOR_ST	Q8IYB3	SRRM1	P42345	MTOR	S292	P293L	293	Missense	proximal	1	no	10.554	4.585	EPSD	COSMIC	6.822	Loss
Atypical_PIKK_FRAP_MTOR_ST	Q8IYB3	SRRM1	P42345	MTOR	S292	R289W	289	Missense	distal	-3	no	10.554	10.338	EPSD	COSMIC;GDSC;CCLE	6.822	Down-regulation
Atypical_PIKK_FRAP_MTOR_ST	Q8IYB3	SRRM1	P42345	MTOR	S292	R291H	291	Missense	proximal	-1	no	10.554	10.595	EPSD	COSMIC	6.822	Up-regulation
Atypical_PIKK_FRAP_MTOR_ST	Q8IYB3	SRRM1	P42345	MTOR	S310	S308L	308	Missense	proximal	-2	no	9.567	9.432	EPSD	COSMIC;GDSC;CCLE	6.822	Down-regulation
Atypical_PIKK_FRAP_MTOR_ST	Q8IYB3	SRRM1	P42345	MTOR	S310	R313W	313	Missense	distal	3	no	9.567	7.807	EPSD	COSMIC	6.822	Down-regulation
Atypical_PIKK_FRAP_MTOR_ST	Q8IYB3	SRRM1	P42345	MTOR	S316	S322T	322	Missense	distal	6	no	15.324	14.410	EPSD	COSMIC	6.822	Down-regulation
Atypical_PIKK_FRAP_MTOR_ST	Q8IYB3	SRRM1	P42345	MTOR	S316	R313W	313	Missense	distal	-3	no	15.324	15.108	EPSD	COSMIC	6.822	Down-regulation
Atypical_PIKK_FRAP_MTOR_ST	Q8IYB3	SRRM1	P42345	MTOR	S316	R319Q	319	Missense	distal	3	no	15.324	14.058	EPSD	COSMIC	6.822	Down-regulation
Atypical_PIKK_FRAP_MTOR_ST	Q8IYB3	SRRM1	P42345	MTOR	S316	P323A	323	Missense	distal	7	no	15.324	14.877	EPSD	COSMIC	6.822	Down-regulation
Atypical_PIKK_FRAP_MTOR_ST	Q8IYB3	SRRM1	P42345	MTOR	S322	R319Q	319	Missense	distal	-3	no	9.409	8.801	EPSD	COSMIC	6.822	Down-regulation
Atypical_PIKK_FRAP_MTOR_ST	Q8IYB3	SRRM1	P42345	MTOR	S322	P323A	323	Missense	proximal	1	no	9.409	0.526	EPSD	COSMIC	6.822	Loss
Atypical_PIKK_FRAP_MTOR_ST	Q8IYB3	SRRM1	P42345	MTOR	T327	S322T	322	Missense	distal	-5	no	6.931	6.937	EPSD	COSMIC	6.822	Up-regulation
Atypical_PIKK_FRAP_MTOR_ST	Q8IYB3	SRRM1	P42345	MTOR	T327	P334S	334	Missense	distal	7	no	6.931	6.910	EPSD	COSMIC	6.822	Down-regulation
Atypical_PIKK_FRAP_MTOR_ST	Q8IYB3	SRRM1	P42345	MTOR	T327	P323A	323	Missense	distal	-4	no	6.931	6.097	EPSD	COSMIC	6.822	Loss
Atypical_PIKK_FRAP_MTOR_ST	Q8IYB3	SRRM1	P42345	MTOR	S354	S359L	359	Missense	distal	5	no	5.360	6.847	EPSD	COSMIC	6.822	Gain
Atypical_PIKK_FRAP_MTOR_ST	Q8IYB3	SRRM1	P42345	MTOR	S359	S360Y	360	Missense	proximal	1	no	3.471	7.164	EPSD	COSMIC	6.822	Gain
Atypical_PIKK_FRAP_MTOR_ST	Q8IYB3	SRRM1	P42345	MTOR	S361	G357W	357	Missense	distal	-4	no	6.033	6.825	EPSD	COSMIC	6.822	Gain
Atypical_PIKK_FRAP_MTOR_ST	Q8IYB3	SRRM1	P42345	MTOR	S363	S364Y	364	Missense	proximal	1	no	5.556	9.250	EPSD	COSMIC	6.822	Gain
Atypical_PIKK_FRAP_MTOR_ST	Q8IYB3	SRRM1	P42345	MTOR	S369	S364Y	364	Missense	distal	-5	no	10.532	11.025	EPSD	COSMIC	6.822	Up-regulation
Atypical_PIKK_FRAP_MTOR_ST	Q8IYB3	SRRM1	P42345	MTOR	S369	P374L	374	Missense	distal	5	no	10.532	11.905	EPSD	COSMIC	6.822	Up-regulation
Atypical_PIKK_FRAP_MTOR_ST	Q8IYB3	SRRM1	P42345	MTOR	S369	P374S	374	Missense	distal	5	no	10.532	10.418	EPSD	COSMIC	6.822	Down-regulation
Atypical_PIKK_FRAP_MTOR_ST	Q8IYB3	SRRM1	P42345	MTOR	S369	P370S	370	Missense	proximal	1	no	10.532	2.008	EPSD	COSMIC	6.822	Loss
Atypical_PIKK_FRAP_MTOR_ST	Q8IYB3	SRRM1	P42345	MTOR	S380	S379N	379	Missense	proximal	-1	no	7.314	7.133	EPSD	COSMIC	6.822	Down-regulation
Atypical_PIKK_FRAP_MTOR_ST	Q8IYB3	SRRM1	P42345	MTOR	S380	P374L	374	Missense	distal	-6	no	7.314	6.539	EPSD	COSMIC	6.822	Loss
Atypical_PIKK_FRAP_MTOR_ST	Q8IYB3	SRRM1	P42345	MTOR	S380	P374S	374	Missense	distal	-6	no	7.314	7.294	EPSD	COSMIC	6.822	Down-regulation
Atypical_PIKK_FRAP_MTOR_ST	Q8IYB3	SRRM1	P42345	MTOR	S402	A405V	405	Missense	distal	3	no	13.734	11.724	EPSD	COSMIC;CCLE	6.822	Down-regulation
Atypical_PIKK_FRAP_MTOR_ST	Q8IYB3	SRRM1	P42345	MTOR	S402	P404H	404	Missense	proximal	2	no	13.734	11.150	EPSD	COSMIC	6.822	Down-regulation
Atypical_PIKK_FRAP_MTOR_ST	Q8IYB3	SRRM1	P42345	MTOR	S402	S402L	402	Missense	central	0	yes	13.734	0.000	EPSD	COSMIC	6.822	Loss
Atypical_PIKK_FRAP_MTOR_ST	Q8IYB3	SRRM1	P42345	MTOR	S402	P408Q	408	Missense	distal	6	no	13.734	12.326	EPSD	COSMIC	6.822	Down-regulation
Atypical_PIKK_FRAP_MTOR_ST	Q8IYB3	SRRM1	P42345	MTOR	S402	P403H	403	Missense	proximal	1	no	13.734	-13.457	EPSD	COSMIC	6.822	Loss
Atypical_PIKK_FRAP_MTOR_ST	Q8IYB3	SRRM1	P42345	MTOR	S402	P407Q	407	Missense	distal	5	no	13.734	13.806	EPSD	COSMIC	6.822	Up-regulation
Atypical_PIKK_FRAP_MTOR_ST	Q8IYB3	SRRM1	P42345	MTOR	S402	P403Q	403	Missense	proximal	1	no	13.734	5.120	EPSD	COSMIC	6.822	Loss
Atypical_PIKK_FRAP_MTOR_ST	Q8IYB3	SRRM1	P42345	MTOR	T406	T411I	411	Missense	distal	5	no	6.403	7.303	EPSD	COSMIC	6.822	Gain
Atypical_PIKK_FRAP_MTOR_ST	Q8IYB3	SRRM1	P42345	MTOR	T406	T411P	411	Missense	distal	5	no	6.403	6.913	EPSD	COSMIC	6.822	Gain
Atypical_PIKK_FRAP_MTOR_ST	Q8IYB3	SRRM1	P42345	MTOR	S414	P415H	415	Missense	proximal	1	no	14.162	-13.029	EPSD	COSMIC	6.822	Loss
Atypical_PIKK_FRAP_MTOR_ST	Q8IYB3	SRRM1	P42345	MTOR	S414	P408Q	408	Missense	distal	-6	no	14.162	13.985	EPSD	COSMIC	6.822	Down-regulation
Atypical_PIKK_FRAP_MTOR_ST	Q8IYB3	SRRM1	P42345	MTOR	S414	T416P	416	Missense	proximal	2	no	14.162	14.716	EPSD	COSMIC	6.822	Up-regulation
Atypical_PIKK_FRAP_MTOR_ST	Q8IYB3	SRRM1	P42345	MTOR	S414	P407Q	407	Missense	distal	-7	no	14.162	13.763	EPSD	COSMIC	6.822	Down-regulation
Atypical_PIKK_FRAP_MTOR_ST	Q8IYB3	SRRM1	P42345	MTOR	S414	T411I	411	Missense	distal	-3	no	14.162	15.037	EPSD	COSMIC	6.822	Up-regulation
Atypical_PIKK_FRAP_MTOR_ST	Q8IYB3	SRRM1	P42345	MTOR	S414	T411P	411	Missense	distal	-3	no	14.162	14.170	EPSD	COSMIC	6.822	Up-regulation
Atypical_PIKK_FRAP_MTOR_ST	Q8IYB3	SRRM1	P42345	MTOR	S431	S436T	436	Missense	distal	5	no	8.122	7.725	EPSD	COSMIC	6.822	Down-regulation
Atypical_PIKK_FRAP_MTOR_ST	Q8IYB3	SRRM1	P42345	MTOR	S431	R424I	424	Missense	distal	-7	no	8.122	7.875	EPSD	COSMIC	6.822	Down-regulation
Atypical_PIKK_FRAP_MTOR_ST	Q8IYB3	SRRM1	P42345	MTOR	S431	G437C	437	Missense	distal	6	no	8.122	6.496	EPSD	COSMIC	6.822	Loss
Atypical_PIKK_FRAP_MTOR_ST	Q8IYB3	SRRM1	P42345	MTOR	S431	G433V	433	Missense	proximal	2	no	8.122	8.285	EPSD	COSMIC	6.822	Up-regulation
Atypical_PIKK_FRAP_MTOR_ST	Q8IYB3	SRRM1	P42345	MTOR	S450	P453T	453	Missense	distal	3	no	8.471	8.078	EPSD	COSMIC	6.822	Down-regulation
Atypical_PIKK_FRAP_MTOR_ST	Q8IYB3	SRRM1	P42345	MTOR	S450	E446Q	446	Missense	distal	-4	no	8.471	8.210	EPSD	COSMIC	6.822	Down-regulation
Atypical_PIKK_FRAP_MTOR_ST	Q8IYB3	SRRM1	P42345	MTOR	S450	A454T	454	Missense	distal	4	no	8.471	9.013	EPSD	COSMIC	6.822	Up-regulation
Atypical_PIKK_FRAP_MTOR_ST	Q8IYB3	SRRM1	P42345	MTOR	S452	P453T	453	Missense	proximal	1	no	8.651	2.379	EPSD	COSMIC	6.822	Loss
Atypical_PIKK_FRAP_MTOR_ST	Q8IYB3	SRRM1	P42345	MTOR	S452	E446Q	446	Missense	distal	-6	no	8.651	8.579	EPSD	COSMIC	6.822	Down-regulation
Atypical_PIKK_FRAP_MTOR_ST	Q8IYB3	SRRM1	P42345	MTOR	S452	A454T	454	Missense	proximal	2	no	8.651	9.355	EPSD	COSMIC	6.822	Up-regulation
Atypical_PIKK_FRAP_MTOR_ST	Q8IYB3	SRRM1	P42345	MTOR	S498	D495Y	495	Missense	distal	-3	no	8.542	8.656	EPSD	COSMIC	6.822	Up-regulation
Atypical_PIKK_FRAP_MTOR_ST	Q8IYB3	SRRM1	P42345	MTOR	S498	E503K	503	Missense	distal	5	no	8.542	8.597	EPSD	COSMIC	6.822	Up-regulation
Atypical_PIKK_FRAP_MTOR_ST	Q8IYB3	SRRM1	P42345	MTOR	S498	S496F	496	Missense	proximal	-2	no	8.542	8.720	EPSD	COSMIC	6.822	Up-regulation
Atypical_PIKK_FRAP_MTOR_ST	Q8IYB3	SRRM1	P42345	MTOR	S498	S500P	500	Missense	proximal	2	no	8.542	9.036	EPSD	COSMIC	6.822	Up-regulation
Atypical_PIKK_FRAP_MTOR_ST	Q8IYB3	SRRM1	P42345	MTOR	S498	S493T	493	Missense	distal	-5	no	8.542	8.548	EPSD	COSMIC	6.822	Up-regulation
Atypical_PIKK_FRAP_MTOR_ST	Q8IYB3	SRRM1	P42345	MTOR	S498	S496P	496	Missense	proximal	-2	no	8.542	8.898	EPSD	COSMIC	6.822	Up-regulation
Atypical_PIKK_FRAP_MTOR_ST	Q8IYB3	SRRM1	P42345	MTOR	S499	S500P	500	Missense	proximal	1	no	4.712	13.236	EPSD	COSMIC	6.822	Gain
Atypical_PIKK_FRAP_MTOR_ST	Q8IYB3	SRRM1	P42345	MTOR	S501	D495Y	495	Missense	distal	-6	no	7.118	6.143	EPSD	COSMIC	6.822	Loss
Atypical_PIKK_FRAP_MTOR_ST	Q8IYB3	SRRM1	P42345	MTOR	S501	S498T	498	Missense	distal	-3	no	7.118	6.679	EPSD	COSMIC	6.822	Loss
Atypical_PIKK_FRAP_MTOR_ST	Q8IYB3	SRRM1	P42345	MTOR	S501	E503K	503	Missense	proximal	2	no	7.118	6.213	EPSD	COSMIC	6.822	Loss
Atypical_PIKK_FRAP_MTOR_ST	Q8IYB3	SRRM1	P42345	MTOR	S501	S496F	496	Missense	distal	-5	no	7.118	7.125	EPSD	COSMIC	6.822	Up-regulation
Atypical_PIKK_FRAP_MTOR_ST	Q8IYB3	SRRM1	P42345	MTOR	S501	S500P	500	Missense	proximal	-1	no	7.118	7.050	EPSD	COSMIC	6.822	Down-regulation
Atypical_PIKK_FRAP_MTOR_ST	Q8IYB3	SRRM1	P42345	MTOR	S501	S496P	496	Missense	distal	-5	no	7.118	7.167	EPSD	COSMIC	6.822	Up-regulation
Atypical_PIKK_FRAP_MTOR_ST	Q8IYB3	SRRM1	P42345	MTOR	S524	R521W	521	Missense	distal	-3	no	11.164	10.948	EPSD	COSMIC;CCLE	6.822	Down-regulation
Atypical_PIKK_FRAP_MTOR_ST	Q8IYB3	SRRM1	P42345	MTOR	S524	R519W	519	Missense	distal	-5	no	11.164	11.221	EPSD	COSMIC	6.822	Up-regulation
Atypical_PIKK_FRAP_MTOR_ST	Q8IYB3	SRRM1	P42345	MTOR	S530	Q537R	537	Missense	distal	7	no	8.980	9.380	EPSD	COSMIC;GDSC;CCLE	6.822	Up-regulation
Atypical_PIKK_FRAP_MTOR_ST	Q8IYB3	SRRM1	P42345	MTOR	S532	Q537R	537	Missense	distal	5	no	8.323	9.131	EPSD	COSMIC;GDSC;CCLE	6.822	Up-regulation
Atypical_PIKK_FRAP_MTOR_ST	Q8IYB3	SRRM1	P42345	MTOR	S541	G544D	544	Missense	distal	3	no	7.464	5.722	EPSD	COSMIC	6.822	Loss
Atypical_PIKK_FRAP_MTOR_ST	Q8IYB3	SRRM1	P42345	MTOR	S541	R547S	547	Missense	distal	6	no	7.464	9.286	EPSD	COSMIC	6.822	Up-regulation
Atypical_PIKK_FRAP_MTOR_ST	Q8IYB3	SRRM1	P42345	MTOR	S541	R546Q	546	Missense	distal	5	no	7.464	6.657	EPSD	COSMIC	6.822	Loss
Atypical_PIKK_FRAP_MTOR_ST	Q8IYB3	SRRM1	P42345	MTOR	S541	Q537R	537	Missense	distal	-4	no	7.464	7.961	EPSD	COSMIC;GDSC;CCLE	6.822	Up-regulation
Atypical_PIKK_FRAP_MTOR_ST	Q8IYB3	SRRM1	P42345	MTOR	S541	R548S	548	Missense	distal	7	no	7.464	6.671	EPSD	COSMIC	6.822	Loss
Atypical_PIKK_FRAP_MTOR_ST	Q8IYB3	SRRM1	P42345	MTOR	S541	R546S	546	Missense	distal	5	no	7.464	6.472	EPSD	COSMIC	6.822	Loss
Atypical_PIKK_FRAP_MTOR_ST	Q8IYB3	SRRM1	P42345	MTOR	S541	R545Q	545	Missense	distal	4	no	7.464	7.596	EPSD	COSMIC	6.822	Up-regulation
Atypical_PIKK_FRAP_MTOR_ST	Q8IYB3	SRRM1	P42345	MTOR	S549	G544D	544	Missense	distal	-5	no	13.097	12.984	EPSD	COSMIC	6.822	Down-regulation
Atypical_PIKK_FRAP_MTOR_ST	Q8IYB3	SRRM1	P42345	MTOR	S549	P554H	554	Missense	distal	5	no	13.097	14.281	EPSD	COSMIC	6.822	Up-regulation
Atypical_PIKK_FRAP_MTOR_ST	Q8IYB3	SRRM1	P42345	MTOR	S549	R547S	547	Missense	proximal	-2	no	13.097	13.225	EPSD	COSMIC	6.822	Up-regulation
Atypical_PIKK_FRAP_MTOR_ST	Q8IYB3	SRRM1	P42345	MTOR	S549	S549N	549	Missense	central	0	yes	13.097	0.000	EPSD	COSMIC	6.822	Loss
Atypical_PIKK_FRAP_MTOR_ST	Q8IYB3	SRRM1	P42345	MTOR	S549	R546Q	546	Missense	distal	-3	no	13.097	12.489	EPSD	COSMIC	6.822	Down-regulation
Atypical_PIKK_FRAP_MTOR_ST	Q8IYB3	SRRM1	P42345	MTOR	S549	R548S	548	Missense	proximal	-1	no	13.097	13.259	EPSD	COSMIC	6.822	Up-regulation
Atypical_PIKK_FRAP_MTOR_ST	Q8IYB3	SRRM1	P42345	MTOR	S549	P553H	553	Missense	distal	4	no	13.097	12.520	EPSD	COSMIC	6.822	Down-regulation
Atypical_PIKK_FRAP_MTOR_ST	Q8IYB3	SRRM1	P42345	MTOR	S549	R546S	546	Missense	distal	-3	no	13.097	12.751	EPSD	COSMIC	6.822	Down-regulation
Atypical_PIKK_FRAP_MTOR_ST	Q8IYB3	SRRM1	P42345	MTOR	S549	R545Q	545	Missense	distal	-4	no	13.097	12.600	EPSD	COSMIC	6.822	Down-regulation
Atypical_PIKK_FRAP_MTOR_ST	Q8IYB3	SRRM1	P42345	MTOR	S551	G544D	544	Missense	distal	-7	no	8.444	9.251	EPSD	COSMIC	6.822	Up-regulation
Atypical_PIKK_FRAP_MTOR_ST	Q8IYB3	SRRM1	P42345	MTOR	S551	P554H	554	Missense	distal	3	no	8.444	8.349	EPSD	COSMIC	6.822	Down-regulation
Atypical_PIKK_FRAP_MTOR_ST	Q8IYB3	SRRM1	P42345	MTOR	S551	R547S	547	Missense	distal	-4	no	8.444	8.330	EPSD	COSMIC	6.822	Down-regulation
Atypical_PIKK_FRAP_MTOR_ST	Q8IYB3	SRRM1	P42345	MTOR	S551	S549N	549	Missense	proximal	-2	no	8.444	7.853	EPSD	COSMIC	6.822	Down-regulation
Atypical_PIKK_FRAP_MTOR_ST	Q8IYB3	SRRM1	P42345	MTOR	S551	R546Q	546	Missense	distal	-5	no	8.444	8.359	EPSD	COSMIC	6.822	Down-regulation
Atypical_PIKK_FRAP_MTOR_ST	Q8IYB3	SRRM1	P42345	MTOR	S551	R548S	548	Missense	distal	-3	no	8.444	8.098	EPSD	COSMIC	6.822	Down-regulation
Atypical_PIKK_FRAP_MTOR_ST	Q8IYB3	SRRM1	P42345	MTOR	S551	P553H	553	Missense	proximal	2	no	8.444	5.859	EPSD	COSMIC	6.822	Loss
Atypical_PIKK_FRAP_MTOR_ST	Q8IYB3	SRRM1	P42345	MTOR	S551	R546S	546	Missense	distal	-5	no	8.444	8.303	EPSD	COSMIC	6.822	Down-regulation
Atypical_PIKK_FRAP_MTOR_ST	Q8IYB3	SRRM1	P42345	MTOR	S551	R558Q	558	Missense	distal	7	no	8.444	8.045	EPSD	COSMIC	6.822	Down-regulation
Atypical_PIKK_FRAP_MTOR_ST	Q8IYB3	SRRM1	P42345	MTOR	S551	R545Q	545	Missense	distal	-6	no	8.444	8.180	EPSD	COSMIC	6.822	Down-regulation
Atypical_PIKK_FRAP_MTOR_ST	Q8IYB3	SRRM1	P42345	MTOR	S551	R558W	558	Missense	distal	7	no	8.444	8.058	EPSD	COSMIC	6.822	Down-regulation
Atypical_PIKK_FRAP_MTOR_ST	Q8IYB3	SRRM1	P42345	MTOR	S551	R557S	557	Missense	distal	6	no	8.444	10.266	EPSD	COSMIC	6.822	Up-regulation
Atypical_PIKK_FRAP_MTOR_ST	Q8IYB3	SRRM1	P42345	MTOR	S560	P566H	566	Missense	distal	6	no	9.545	8.068	EPSD	COSMIC	6.822	Down-regulation
Atypical_PIKK_FRAP_MTOR_ST	Q8IYB3	SRRM1	P42345	MTOR	S560	A564P	564	Missense	distal	4	no	9.545	9.763	EPSD	COSMIC	6.822	Up-regulation
Atypical_PIKK_FRAP_MTOR_ST	Q8IYB3	SRRM1	P42345	MTOR	S560	P554H	554	Missense	distal	-6	no	9.545	8.825	EPSD	COSMIC	6.822	Down-regulation
Atypical_PIKK_FRAP_MTOR_ST	Q8IYB3	SRRM1	P42345	MTOR	S560	R559Q	559	Missense	proximal	-1	no	9.545	9.563	EPSD	COSMIC	6.822	Up-regulation
Atypical_PIKK_FRAP_MTOR_ST	Q8IYB3	SRRM1	P42345	MTOR	S560	P565H	565	Missense	distal	5	no	9.545	10.728	EPSD	COSMIC	6.822	Up-regulation
Atypical_PIKK_FRAP_MTOR_ST	Q8IYB3	SRRM1	P42345	MTOR	S560	P553H	553	Missense	distal	-7	no	9.545	8.873	EPSD	COSMIC	6.822	Down-regulation
Atypical_PIKK_FRAP_MTOR_ST	Q8IYB3	SRRM1	P42345	MTOR	S560	P565S	565	Missense	distal	5	no	9.545	9.431	EPSD	COSMIC	6.822	Down-regulation
Atypical_PIKK_FRAP_MTOR_ST	Q8IYB3	SRRM1	P42345	MTOR	S560	R558Q	558	Missense	proximal	-2	no	9.545	9.884	EPSD	COSMIC	6.822	Up-regulation
Atypical_PIKK_FRAP_MTOR_ST	Q8IYB3	SRRM1	P42345	MTOR	S560	P561Q	561	Missense	proximal	1	no	9.545	0.931	EPSD	COSMIC	6.822	Loss
Atypical_PIKK_FRAP_MTOR_ST	Q8IYB3	SRRM1	P42345	MTOR	S560	R558W	558	Missense	proximal	-2	no	9.545	9.246	EPSD	COSMIC	6.822	Down-regulation
Atypical_PIKK_FRAP_MTOR_ST	Q8IYB3	SRRM1	P42345	MTOR	S560	P563H	563	Missense	distal	3	no	9.545	9.449	EPSD	COSMIC	6.822	Down-regulation
Atypical_PIKK_FRAP_MTOR_ST	Q8IYB3	SRRM1	P42345	MTOR	S560	R557S	557	Missense	distal	-3	no	9.545	9.199	EPSD	COSMIC	6.822	Down-regulation
Atypical_PIKK_FRAP_MTOR_ST	Q8IYB3	SRRM1	P42345	MTOR	S562	P566H	566	Missense	distal	4	no	7.199	6.622	EPSD	COSMIC	6.822	Loss
Atypical_PIKK_FRAP_MTOR_ST	Q8IYB3	SRRM1	P42345	MTOR	S562	A564P	564	Missense	proximal	2	no	7.199	8.457	EPSD	COSMIC	6.822	Up-regulation
Atypical_PIKK_FRAP_MTOR_ST	Q8IYB3	SRRM1	P42345	MTOR	S562	R559Q	559	Missense	distal	-3	no	7.199	6.590	EPSD	COSMIC	6.822	Loss
Atypical_PIKK_FRAP_MTOR_ST	Q8IYB3	SRRM1	P42345	MTOR	S562	R569L	569	Missense	distal	7	no	7.199	7.383	EPSD	COSMIC	6.822	Up-regulation
Atypical_PIKK_FRAP_MTOR_ST	Q8IYB3	SRRM1	P42345	MTOR	S562	P565H	565	Missense	distal	3	no	7.199	7.103	EPSD	COSMIC	6.822	Down-regulation
Atypical_PIKK_FRAP_MTOR_ST	Q8IYB3	SRRM1	P42345	MTOR	S562	P565S	565	Missense	distal	3	no	7.199	7.213	EPSD	COSMIC	6.822	Up-regulation
Atypical_PIKK_FRAP_MTOR_ST	Q8IYB3	SRRM1	P42345	MTOR	S562	R558Q	558	Missense	distal	-4	no	7.199	6.702	EPSD	COSMIC	6.822	Loss
Atypical_PIKK_FRAP_MTOR_ST	Q8IYB3	SRRM1	P42345	MTOR	S562	P561Q	561	Missense	proximal	-1	no	7.199	7.124	EPSD	COSMIC	6.822	Down-regulation
Atypical_PIKK_FRAP_MTOR_ST	Q8IYB3	SRRM1	P42345	MTOR	S562	R558W	558	Missense	distal	-4	no	7.199	7.309	EPSD	COSMIC	6.822	Up-regulation
Atypical_PIKK_FRAP_MTOR_ST	Q8IYB3	SRRM1	P42345	MTOR	S562	P563H	563	Missense	proximal	1	no	7.199	-19.992	EPSD	COSMIC	6.822	Loss
Atypical_PIKK_FRAP_MTOR_ST	Q8IYB3	SRRM1	P42345	MTOR	S562	R557S	557	Missense	distal	-5	no	7.199	7.057	EPSD	COSMIC	6.822	Down-regulation
Atypical_PIKK_FRAP_MTOR_ST	Q8IYB3	SRRM1	P42345	MTOR	S562	R568W	568	Missense	distal	6	no	7.199	7.729	EPSD	COSMIC	6.822	Up-regulation
Atypical_PIKK_FRAP_MTOR_ST	Q8IYB3	SRRM1	P42345	MTOR	T572	R570L	570	Missense	proximal	-2	no	7.638	7.631	EPSD;PhosphoSitePlus	COSMIC	6.822	Down-regulation
Atypical_PIKK_FRAP_MTOR_ST	Q8IYB3	SRRM1	P42345	MTOR	T572	P566H	566	Missense	distal	-6	no	7.638	6.918	EPSD;PhosphoSitePlus	COSMIC	6.822	Down-regulation
Atypical_PIKK_FRAP_MTOR_ST	Q8IYB3	SRRM1	P42345	MTOR	T572	R579G	579	Missense	distal	7	no	7.638	7.230	EPSD;PhosphoSitePlus	COSMIC	6.822	Down-regulation
Atypical_PIKK_FRAP_MTOR_ST	Q8IYB3	SRRM1	P42345	MTOR	T572	R569L	569	Missense	distal	-3	no	7.638	7.707	EPSD;PhosphoSitePlus	COSMIC	6.822	Up-regulation
Atypical_PIKK_FRAP_MTOR_ST	Q8IYB3	SRRM1	P42345	MTOR	T572	P565H	565	Missense	distal	-7	no	7.638	6.967	EPSD;PhosphoSitePlus	COSMIC	6.822	Down-regulation
Atypical_PIKK_FRAP_MTOR_ST	Q8IYB3	SRRM1	P42345	MTOR	T572	P565S	565	Missense	distal	-7	no	7.638	8.075	EPSD;PhosphoSitePlus	COSMIC	6.822	Up-regulation
Atypical_PIKK_FRAP_MTOR_ST	Q8IYB3	SRRM1	P42345	MTOR	T572	R570M	570	Missense	proximal	-2	no	7.638	7.241	EPSD;PhosphoSitePlus	COSMIC	6.822	Down-regulation
Atypical_PIKK_FRAP_MTOR_ST	Q8IYB3	SRRM1	P42345	MTOR	T572	R578G	578	Missense	distal	6	no	7.638	9.390	EPSD;PhosphoSitePlus	COSMIC	6.822	Up-regulation
Atypical_PIKK_FRAP_MTOR_ST	Q8IYB3	SRRM1	P42345	MTOR	T572	R568W	568	Missense	distal	-4	no	7.638	7.748	EPSD;PhosphoSitePlus	COSMIC	6.822	Up-regulation
Atypical_PIKK_FRAP_MTOR_ST	Q8IYB3	SRRM1	P42345	MTOR	T574	R570L	570	Missense	distal	-4	no	9.794	9.364	PhosphoSitePlus;EPSD	COSMIC	6.822	Down-regulation
Atypical_PIKK_FRAP_MTOR_ST	Q8IYB3	SRRM1	P42345	MTOR	T574	R579G	579	Missense	distal	5	no	9.794	9.464	PhosphoSitePlus;EPSD	COSMIC	6.822	Down-regulation
Atypical_PIKK_FRAP_MTOR_ST	Q8IYB3	SRRM1	P42345	MTOR	T574	R569L	569	Missense	distal	-5	no	9.794	9.629	PhosphoSitePlus;EPSD	COSMIC	6.822	Down-regulation
Atypical_PIKK_FRAP_MTOR_ST	Q8IYB3	SRRM1	P42345	MTOR	T574	R570M	570	Missense	distal	-4	no	9.794	8.952	PhosphoSitePlus;EPSD	COSMIC	6.822	Down-regulation
Atypical_PIKK_FRAP_MTOR_ST	Q8IYB3	SRRM1	P42345	MTOR	T574	R578G	578	Missense	distal	4	no	9.794	9.844	PhosphoSitePlus;EPSD	COSMIC	6.822	Up-regulation
Atypical_PIKK_FRAP_MTOR_ST	Q8IYB3	SRRM1	P42345	MTOR	T574	R580M	580	Missense	distal	6	no	9.794	10.232	PhosphoSitePlus;EPSD	COSMIC	6.822	Up-regulation
Atypical_PIKK_FRAP_MTOR_ST	Q8IYB3	SRRM1	P42345	MTOR	T574	R568W	568	Missense	distal	-6	no	9.794	10.167	PhosphoSitePlus;EPSD	COSMIC	6.822	Up-regulation
Atypical_PIKK_FRAP_MTOR_ST	Q8IYB3	SRRM1	P42345	MTOR	T581	P585L	585	Missense	distal	4	no	8.125	7.741	EPSD	COSMIC;CCLE	6.822	Down-regulation
Atypical_PIKK_FRAP_MTOR_ST	Q8IYB3	SRRM1	P42345	MTOR	T581	R587H	587	Missense	distal	6	no	8.125	8.441	EPSD	COSMIC	6.822	Up-regulation
Atypical_PIKK_FRAP_MTOR_ST	Q8IYB3	SRRM1	P42345	MTOR	T581	R579G	579	Missense	proximal	-2	no	8.125	8.982	EPSD	COSMIC	6.822	Up-regulation
Atypical_PIKK_FRAP_MTOR_ST	Q8IYB3	SRRM1	P42345	MTOR	T581	P584L	584	Missense	distal	3	no	8.125	5.870	EPSD	COSMIC	6.822	Loss
Atypical_PIKK_FRAP_MTOR_ST	Q8IYB3	SRRM1	P42345	MTOR	T581	R588H	588	Missense	distal	7	no	8.125	7.968	EPSD	COSMIC	6.822	Down-regulation
Atypical_PIKK_FRAP_MTOR_ST	Q8IYB3	SRRM1	P42345	MTOR	T581	R578G	578	Missense	distal	-3	no	8.125	8.151	EPSD	COSMIC	6.822	Up-regulation
Atypical_PIKK_FRAP_MTOR_ST	Q8IYB3	SRRM1	P42345	MTOR	T581	R588C	588	Missense	distal	7	no	8.125	8.555	EPSD	COSMIC	6.822	Up-regulation
Atypical_PIKK_FRAP_MTOR_ST	Q8IYB3	SRRM1	P42345	MTOR	T581	R580M	580	Missense	proximal	-1	no	8.125	8.184	EPSD	COSMIC	6.822	Up-regulation
Atypical_PIKK_FRAP_MTOR_ST	Q8IYB3	SRRM1	P42345	MTOR	T581	R588G	588	Missense	distal	7	no	8.125	7.717	EPSD	COSMIC	6.822	Down-regulation
Atypical_PIKK_FRAP_MTOR_ST	Q8IYB3	SRRM1	P42345	MTOR	T581	R588Q	588	Missense	distal	7	no	8.125	7.725	EPSD	COSMIC	6.822	Down-regulation
Atypical_PIKK_FRAP_MTOR_ST	Q8IYB3	SRRM1	P42345	MTOR	S583	P585L	585	Missense	proximal	2	no	12.711	12.021	EPSD	COSMIC;CCLE	6.822	Down-regulation
Atypical_PIKK_FRAP_MTOR_ST	Q8IYB3	SRRM1	P42345	MTOR	S583	R587H	587	Missense	distal	4	no	12.711	12.452	EPSD	COSMIC	6.822	Down-regulation
Atypical_PIKK_FRAP_MTOR_ST	Q8IYB3	SRRM1	P42345	MTOR	S583	R579G	579	Missense	distal	-4	no	12.711	12.029	EPSD	COSMIC	6.822	Down-regulation
Atypical_PIKK_FRAP_MTOR_ST	Q8IYB3	SRRM1	P42345	MTOR	S583	R589C	589	Missense	distal	6	no	12.711	12.838	EPSD	COSMIC	6.822	Up-regulation
Atypical_PIKK_FRAP_MTOR_ST	Q8IYB3	SRRM1	P42345	MTOR	S583	P584L	584	Missense	proximal	1	no	12.711	6.742	EPSD	COSMIC	6.822	Loss
Atypical_PIKK_FRAP_MTOR_ST	Q8IYB3	SRRM1	P42345	MTOR	S583	R588H	588	Missense	distal	5	no	12.711	13.016	EPSD	COSMIC	6.822	Up-regulation
Atypical_PIKK_FRAP_MTOR_ST	Q8IYB3	SRRM1	P42345	MTOR	S583	R578G	578	Missense	distal	-5	no	12.711	12.637	EPSD	COSMIC	6.822	Down-regulation
Atypical_PIKK_FRAP_MTOR_ST	Q8IYB3	SRRM1	P42345	MTOR	S583	R588C	588	Missense	distal	5	no	12.711	12.495	EPSD	COSMIC	6.822	Down-regulation
Atypical_PIKK_FRAP_MTOR_ST	Q8IYB3	SRRM1	P42345	MTOR	S583	R580M	580	Missense	distal	-3	no	12.711	11.512	EPSD	COSMIC	6.822	Down-regulation
Atypical_PIKK_FRAP_MTOR_ST	Q8IYB3	SRRM1	P42345	MTOR	S583	R588G	588	Missense	distal	5	no	12.711	12.381	EPSD	COSMIC	6.822	Down-regulation
Atypical_PIKK_FRAP_MTOR_ST	Q8IYB3	SRRM1	P42345	MTOR	S583	R588Q	588	Missense	distal	5	no	12.711	11.904	EPSD	COSMIC	6.822	Down-regulation
Atypical_PIKK_FRAP_MTOR_ST	Q8IYB3	SRRM1	P42345	MTOR	S590	P585L	585	Missense	distal	-5	no	12.644	12.573	EPSD	COSMIC;CCLE	6.822	Down-regulation
Atypical_PIKK_FRAP_MTOR_ST	Q8IYB3	SRRM1	P42345	MTOR	S590	R587H	587	Missense	distal	-3	no	12.644	11.897	EPSD	COSMIC	6.822	Down-regulation
Atypical_PIKK_FRAP_MTOR_ST	Q8IYB3	SRRM1	P42345	MTOR	S590	R589C	589	Missense	proximal	-1	no	12.644	12.817	EPSD	COSMIC	6.822	Up-regulation
Atypical_PIKK_FRAP_MTOR_ST	Q8IYB3	SRRM1	P42345	MTOR	S590	P584L	584	Missense	distal	-6	no	12.644	11.870	EPSD	COSMIC	6.822	Down-regulation
Atypical_PIKK_FRAP_MTOR_ST	Q8IYB3	SRRM1	P42345	MTOR	S590	R588H	588	Missense	proximal	-2	no	12.644	12.414	EPSD	COSMIC	6.822	Down-regulation
Atypical_PIKK_FRAP_MTOR_ST	Q8IYB3	SRRM1	P42345	MTOR	S590	R588C	588	Missense	proximal	-2	no	12.644	12.922	EPSD	COSMIC	6.822	Up-regulation
Atypical_PIKK_FRAP_MTOR_ST	Q8IYB3	SRRM1	P42345	MTOR	S590	R588G	588	Missense	proximal	-2	no	12.644	13.502	EPSD	COSMIC	6.822	Up-regulation
Atypical_PIKK_FRAP_MTOR_ST	Q8IYB3	SRRM1	P42345	MTOR	S590	R588Q	588	Missense	proximal	-2	no	12.644	12.984	EPSD	COSMIC	6.822	Up-regulation
Atypical_PIKK_FRAP_MTOR_ST	Q8IYB3	SRRM1	P42345	MTOR	S592	P585L	585	Missense	distal	-7	no	8.159	8.027	EPSD	COSMIC;CCLE	6.822	Down-regulation
Atypical_PIKK_FRAP_MTOR_ST	Q8IYB3	SRRM1	P42345	MTOR	S592	R587H	587	Missense	distal	-5	no	8.159	8.164	EPSD	COSMIC	6.822	Up-regulation
Atypical_PIKK_FRAP_MTOR_ST	Q8IYB3	SRRM1	P42345	MTOR	S592	P599S	599	Missense	distal	7	no	8.159	8.138	EPSD	COSMIC	6.822	Down-regulation
Atypical_PIKK_FRAP_MTOR_ST	Q8IYB3	SRRM1	P42345	MTOR	S592	R589C	589	Missense	distal	-3	no	8.159	7.448	EPSD	COSMIC	6.822	Down-regulation
Atypical_PIKK_FRAP_MTOR_ST	Q8IYB3	SRRM1	P42345	MTOR	S592	R588H	588	Missense	distal	-4	no	8.159	6.966	EPSD	COSMIC	6.822	Down-regulation
Atypical_PIKK_FRAP_MTOR_ST	Q8IYB3	SRRM1	P42345	MTOR	S592	P598S	598	Missense	distal	6	no	8.159	8.189	EPSD	COSMIC	6.822	Up-regulation
Atypical_PIKK_FRAP_MTOR_ST	Q8IYB3	SRRM1	P42345	MTOR	S592	R588C	588	Missense	distal	-4	no	8.159	6.220	EPSD	COSMIC	6.822	Loss
Atypical_PIKK_FRAP_MTOR_ST	Q8IYB3	SRRM1	P42345	MTOR	S592	R588G	588	Missense	distal	-4	no	8.159	7.478	EPSD	COSMIC	6.822	Down-regulation
Atypical_PIKK_FRAP_MTOR_ST	Q8IYB3	SRRM1	P42345	MTOR	S592	R588Q	588	Missense	distal	-4	no	8.159	7.662	EPSD	COSMIC	6.822	Down-regulation
Atypical_PIKK_FRAP_MTOR_ST	Q8IYB3	SRRM1	P42345	MTOR	S605	R602G	602	Missense	distal	-3	no	12.357	12.383	EPSD	COSMIC	6.822	Up-regulation
Atypical_PIKK_FRAP_MTOR_ST	Q8IYB3	SRRM1	P42345	MTOR	S605	P599S	599	Missense	distal	-6	no	12.357	12.337	EPSD	COSMIC	6.822	Down-regulation
Atypical_PIKK_FRAP_MTOR_ST	Q8IYB3	SRRM1	P42345	MTOR	S605	P598S	598	Missense	distal	-7	no	12.357	12.794	EPSD	COSMIC	6.822	Up-regulation
Atypical_PIKK_FRAP_MTOR_ST	Q8IYB3	SRRM1	P42345	MTOR	S605	P608S	608	Missense	distal	3	no	12.357	12.371	EPSD	COSMIC	6.822	Up-regulation
Atypical_PIKK_FRAP_MTOR_ST	Q8IYB3	SRRM1	P42345	MTOR	S607	R602G	602	Missense	distal	-5	no	8.255	8.181	EPSD	COSMIC	6.822	Down-regulation
Atypical_PIKK_FRAP_MTOR_ST	Q8IYB3	SRRM1	P42345	MTOR	S607	T614M	614	Missense	distal	7	no	8.255	9.341	EPSD	COSMIC	6.822	Up-regulation
Atypical_PIKK_FRAP_MTOR_ST	Q8IYB3	SRRM1	P42345	MTOR	S607	P608S	608	Missense	proximal	1	no	8.255	-0.269	EPSD	COSMIC	6.822	Loss
Atypical_PIKK_FRAP_MTOR_ST	Q8IYB3	SRRM1	P42345	MTOR	S616	T614M	614	Missense	proximal	-2	no	12.806	12.218	EPSD	COSMIC	6.822	Down-regulation
Atypical_PIKK_FRAP_MTOR_ST	Q8IYB3	SRRM1	P42345	MTOR	S616	P619L	619	Missense	distal	3	no	12.806	10.552	EPSD	COSMIC	6.822	Down-regulation
Atypical_PIKK_FRAP_MTOR_ST	Q8IYB3	SRRM1	P42345	MTOR	S616	P618L	618	Missense	proximal	2	no	12.806	12.117	EPSD	COSMIC	6.822	Down-regulation
Atypical_PIKK_FRAP_MTOR_ST	Q8IYB3	SRRM1	P42345	MTOR	S626	P619L	619	Missense	distal	-7	no	7.806	7.674	EPSD	COSMIC	6.822	Down-regulation
Atypical_PIKK_FRAP_MTOR_ST	Q8IYB3	SRRM1	P42345	MTOR	S638	S645F	645	Missense	distal	7	no	11.852	12.432	EPSD	COSMIC	6.822	Up-regulation
Atypical_PIKK_FRAP_MTOR_ST	Q8IYB3	SRRM1	P42345	MTOR	S646	R652H	652	Missense	distal	6	no	9.843	10.159	EPSD	COSMIC	6.822	Up-regulation
Atypical_PIKK_FRAP_MTOR_ST	Q8IYB3	SRRM1	P42345	MTOR	S646	R651H	651	Missense	distal	5	no	9.843	10.148	EPSD	COSMIC	6.822	Up-regulation
Atypical_PIKK_FRAP_MTOR_ST	Q8IYB3	SRRM1	P42345	MTOR	S646	R651C	651	Missense	distal	5	no	9.843	9.627	EPSD	COSMIC	6.822	Down-regulation
Atypical_PIKK_FRAP_MTOR_ST	Q8IYB3	SRRM1	P42345	MTOR	S646	S645F	645	Missense	proximal	-1	no	9.843	9.659	EPSD	COSMIC	6.822	Down-regulation
Atypical_PIKK_FRAP_MTOR_ST	Q8IYB3	SRRM1	P42345	MTOR	S653	L656S	656	Missense	distal	3	no	6.235	8.504	EPSD	COSMIC	6.822	Gain
Atypical_PIKK_FRAP_MTOR_ST	Q8IYB3	SRRM1	P42345	MTOR	S653	K659E	659	Missense	distal	6	no	6.235	7.139	EPSD	COSMIC	6.822	Gain
Atypical_PIKK_FRAP_MTOR_ST	Q8IYB3	SRRM1	P42345	MTOR	S685	P688H	688	Missense	distal	3	no	10.720	10.624	EPSD	COSMIC	6.822	Down-regulation
Atypical_PIKK_FRAP_MTOR_ST	Q8IYB3	SRRM1	P42345	MTOR	S696	P699L	699	Missense	distal	3	no	9.815	7.560	EPSD	COSMIC	6.822	Down-regulation
Atypical_PIKK_FRAP_MTOR_ST	Q8IYB3	SRRM1	P42345	MTOR	S696	P698L	698	Missense	proximal	2	no	9.815	9.125	EPSD	COSMIC	6.822	Down-regulation
Atypical_PIKK_FRAP_MTOR_ST	Q8IYB3	SRRM1	P42345	MTOR	S696	P697H	697	Missense	proximal	1	no	9.815	-17.376	EPSD	COSMIC	6.822	Loss
Atypical_PIKK_FRAP_MTOR_ST	Q8IYB3	SRRM1	P42345	MTOR	S713	P714S	714	Missense	proximal	1	no	9.994	1.470	EPSD	COSMIC	6.822	Loss
Atypical_PIKK_FRAP_MTOR_ST	Q8IYB3	SRRM1	P42345	MTOR	S713	R710Q	710	Missense	distal	-3	no	9.994	9.386	EPSD	COSMIC	6.822	Down-regulation
Atypical_PIKK_FRAP_MTOR_ST	Q8IYB3	SRRM1	P42345	MTOR	S713	P708L	708	Missense	distal	-5	no	9.994	9.922	EPSD	COSMIC	6.822	Down-regulation
Atypical_PIKK_FRAP_MTOR_ST	Q8IYB3	SRRM1	P42345	MTOR	S715	P714S	714	Missense	proximal	-1	no	11.835	11.903	EPSD	COSMIC	6.822	Up-regulation
Atypical_PIKK_FRAP_MTOR_ST	Q8IYB3	SRRM1	P42345	MTOR	S715	R710Q	710	Missense	distal	-5	no	11.835	11.750	EPSD	COSMIC	6.822	Down-regulation
Atypical_PIKK_FRAP_MTOR_ST	Q8IYB3	SRRM1	P42345	MTOR	S715	P708L	708	Missense	distal	-7	no	11.835	11.702	EPSD	COSMIC	6.822	Down-regulation
Atypical_PIKK_FRAP_MTOR_ST	Q8IYB3	SRRM1	P42345	MTOR	T727	P728Q	728	Missense	proximal	1	no	10.270	1.656	EPSD	COSMIC	6.822	Loss
Atypical_PIKK_FRAP_MTOR_ST	Q8IYB3	SRRM1	P42345	MTOR	T727	E729K	729	Missense	proximal	2	no	10.270	9.365	EPSD	COSMIC	6.822	Down-regulation
Atypical_PIKK_FRAP_MTOR_ST	Q8IYB3	SRRM1	P42345	MTOR	T727	P728L	728	Missense	proximal	1	no	10.270	4.301	EPSD	COSMIC	6.822	Loss
Atypical_PIKK_FRAP_MTOR_ST	Q8IYB3	SRRM1	P42345	MTOR	T727	K731T	731	Missense	distal	4	no	10.270	10.608	EPSD	COSMIC	6.822	Up-regulation
Atypical_PIKK_FRAP_MTOR_ST	Q8IYB3	SRRM1	P42345	MTOR	S738	P741L	741	Missense	distal	3	no	9.279	7.024	EPSD	COSMIC	6.822	Down-regulation
Atypical_PIKK_FRAP_MTOR_ST	Q8IYB3	SRRM1	P42345	MTOR	S738	S740N	740	Missense	proximal	2	no	9.279	7.877	EPSD	COSMIC	6.822	Down-regulation
Atypical_PIKK_FRAP_MTOR_ST	Q8IYB3	SRRM1	P42345	MTOR	S738	P739S	739	Missense	proximal	1	no	9.279	0.755	EPSD	COSMIC	6.822	Loss
Atypical_PIKK_FRAP_MTOR_ST	Q8IYB3	SRRM1	P42345	MTOR	S738	R745T	745	Missense	distal	7	no	9.279	7.540	EPSD	COSMIC	6.822	Down-regulation
Atypical_PIKK_FRAP_MTOR_ST	Q8IYB3	SRRM1	P42345	MTOR	S738	K731T	731	Missense	distal	-7	no	9.279	9.943	EPSD	COSMIC	6.822	Up-regulation
Atypical_PIKK_FRAP_MTOR_ST	Q8IYB3	SRRM1	P42345	MTOR	S740	P741L	741	Missense	proximal	1	no	8.098	2.129	EPSD	COSMIC	6.822	Loss
Atypical_PIKK_FRAP_MTOR_ST	Q8IYB3	SRRM1	P42345	MTOR	S740	S740N	740	Missense	central	0	yes	8.098	0.000	EPSD	COSMIC	6.822	Loss
Atypical_PIKK_FRAP_MTOR_ST	Q8IYB3	SRRM1	P42345	MTOR	S740	P739S	739	Missense	proximal	-1	no	8.098	8.166	EPSD	COSMIC	6.822	Up-regulation
Atypical_PIKK_FRAP_MTOR_ST	Q8IYB3	SRRM1	P42345	MTOR	S740	R745T	745	Missense	distal	5	no	8.098	6.708	EPSD	COSMIC	6.822	Loss
Atypical_PIKK_FRAP_MTOR_ST	Q8IYB3	SRRM1	P42345	MTOR	S756	R751Q	751	Missense	distal	-5	no	10.971	10.886	EPSD	COSMIC	6.822	Down-regulation
Atypical_PIKK_FRAP_MTOR_ST	Q8IYB3	SRRM1	P42345	MTOR	S769	P768L	768	Missense	proximal	-1	no	6.891	6.757	EPSD	COSMIC	6.822	Loss
Atypical_PIKK_FRAP_MTOR_ST	Q8IYB3	SRRM1	P42345	MTOR	S769	V771I	771	Missense	proximal	2	no	6.891	6.860	EPSD	COSMIC;GDSC	6.822	Down-regulation
Atypical_PIKK_FRAP_MTOR_ST	Q8IYB3	SRRM1	P42345	MTOR	S769	P770L	770	Missense	proximal	1	no	6.891	0.922	EPSD	COSMIC	6.822	Loss
Atypical_PIKK_FRAP_MTOR_ST	Q8IYB3	SRRM1	P42345	MTOR	S769	P767L	767	Missense	proximal	-2	no	6.891	6.401	EPSD	COSMIC	6.822	Loss
Atypical_PIKK_FRAP_MTOR_ST	Q8IYB3	SRRM1	P42345	MTOR	S769	P767S	767	Missense	proximal	-2	no	6.891	6.535	EPSD	COSMIC	6.822	Loss
Atypical_PIKK_FRAP_MTOR_ST	Q8IYB3	SRRM1	P42345	MTOR	S775	P768L	768	Missense	distal	-7	no	9.889	9.756	EPSD	COSMIC	6.822	Down-regulation
Atypical_PIKK_FRAP_MTOR_ST	Q8IYB3	SRRM1	P42345	MTOR	S775	V771I	771	Missense	distal	-4	no	9.889	9.646	EPSD	COSMIC;GDSC	6.822	Down-regulation
Atypical_PIKK_FRAP_MTOR_ST	Q8IYB3	SRRM1	P42345	MTOR	S775	P770L	770	Missense	distal	-5	no	9.889	9.817	EPSD	COSMIC	6.822	Down-regulation
Atypical_PIKK_FRAP_MTOR_ST	Q8IYB3	SRRM1	P42345	MTOR	S791	K790T	790	Missense	proximal	-1	no	9.063	9.129	EPSD	COSMIC	6.822	Up-regulation
Atypical_PIKK_FRAP_MTOR_ST	Q8IYB3	SRRM1	P42345	MTOR	S795	K790T	790	Missense	distal	-5	no	11.414	11.434	EPSD	COSMIC	6.822	Up-regulation
Atypical_PIKK_FRAP_MTOR_ST	Q8IYB3	SRRM1	P42345	MTOR	S797	K790T	790	Missense	distal	-7	no	16.250	16.914	EPSD	COSMIC	6.822	Up-regulation
Atypical_PIKK_FRAP_MTOR_ST	Q8IYB3	SRRM1	P42345	MTOR	S901	P902L	902	Missense	proximal	1	no	17.196	11.227	EPSD	COSMIC	6.822	Down-regulation
Atypical_PIKK_FRAP_MTOR_ST	P51397	DAP	P42345	MTOR	S91	S85R	85	Missense	distal	-6	no	15.928	16.035	EPSD	COSMIC	6.822	Up-regulation
Atypical_PIKK_FRAP_MTOR_ST	P51397	DAP	P42345	MTOR	S91	D87E	87	Missense	distal	-4	no	15.928	14.778	EPSD	COSMIC	6.822	Down-regulation
Atypical_PIKK_FRAP_MTOR_ST	P51397	DAP	P42345	MTOR	S91	A84V	84	Missense	distal	-7	no	15.928	16.040	EPSD	COSMIC	6.822	Up-regulation
Atypical_PIKK_FRAP_MTOR_ST	P51397	DAP	P42345	MTOR	S91	S85C	85	Missense	distal	-6	no	15.928	16.162	EPSD	COSMIC	6.822	Up-regulation
Atypical_PIKK_FRAP_MTOR_ST	O95817	BAG3	P42345	MTOR	S173	R170L	170	Missense	distal	-3	no	9.376	9.445	EPSD	COSMIC	6.822	Up-regulation
Atypical_PIKK_FRAP_MTOR_ST	O95817	BAG3	P42345	MTOR	S187	R193T	193	Missense	distal	6	no	6.672	7.580	EPSD	COSMIC	6.822	Gain
Atypical_PIKK_FRAP_MTOR_ST	O95817	BAG3	P42345	MTOR	S207	P209L	209	Missense	proximal	2	no	7.046	6.357	EPSD	COSMIC	6.822	Loss
Atypical_PIKK_FRAP_MTOR_ST	O95817	BAG3	P42345	MTOR	S207	I208M	208	Missense	proximal	1	no	7.046	6.173	EPSD	COSMIC	6.822	Loss
Atypical_PIKK_FRAP_MTOR_ST	O95817	BAG3	P42345	MTOR	S207	Y205C	205	Missense	proximal	-2	no	7.046	7.739	EPSD	COSMIC	6.822	Up-regulation
Atypical_PIKK_FRAP_MTOR_ST	O95817	BAG3	P42345	MTOR	S264	R261W	261	Missense	distal	-3	no	10.328	10.112	EPSD	COSMIC;CCLE	6.822	Down-regulation
Atypical_PIKK_FRAP_MTOR_ST	O95817	BAG3	P42345	MTOR	S264	P265L	265	Missense	proximal	1	no	10.328	4.359	EPSD	COSMIC	6.822	Loss
Atypical_PIKK_FRAP_MTOR_ST	O95817	BAG3	P42345	MTOR	S264	S269F	269	Missense	distal	5	no	10.328	10.914	EPSD	COSMIC	6.822	Up-regulation
Atypical_PIKK_FRAP_MTOR_ST	O95817	BAG3	P42345	MTOR	S264	R258W	258	Missense	distal	-6	no	10.328	10.701	EPSD	COSMIC	6.822	Up-regulation
Atypical_PIKK_FRAP_MTOR_ST	O95817	BAG3	P42345	MTOR	S269	S275I	275	Missense	distal	6	no	7.798	6.934	EPSD	COSMIC	6.822	Down-regulation
Atypical_PIKK_FRAP_MTOR_ST	O95817	BAG3	P42345	MTOR	S269	P265L	265	Missense	distal	-4	no	7.798	7.612	EPSD	COSMIC	6.822	Down-regulation
Atypical_PIKK_FRAP_MTOR_ST	O95817	BAG3	P42345	MTOR	S269	S269F	269	Missense	central	0	yes	7.798	0.000	EPSD	COSMIC	6.822	Loss
Atypical_PIKK_FRAP_MTOR_ST	O95817	BAG3	P42345	MTOR	S279	S275I	275	Missense	distal	-4	no	12.887	11.961	EPSD	COSMIC	6.822	Down-regulation
Atypical_PIKK_FRAP_MTOR_ST	O95817	BAG3	P42345	MTOR	S279	R282K	282	Missense	distal	3	no	12.887	11.788	EPSD	COSMIC	6.822	Down-regulation
Atypical_PIKK_FRAP_MTOR_ST	O95817	BAG3	P42345	MTOR	T285	R282K	282	Missense	distal	-3	no	8.855	8.140	PhosphoSitePlus;EPSD	COSMIC	6.822	Down-regulation
Atypical_PIKK_FRAP_MTOR_ST	O95817	BAG3	P42345	MTOR	S289	R282K	282	Missense	distal	-7	no	14.805	14.951	EPSD;PhosphoSitePlus	COSMIC	6.822	Up-regulation
Atypical_PIKK_FRAP_MTOR_ST	O95817	BAG3	P42345	MTOR	S377	P376S	376	Missense	proximal	-1	no	9.016	9.084	EPSD	COSMIC	6.822	Up-regulation
Atypical_PIKK_FRAP_MTOR_ST	O95817	BAG3	P42345	MTOR	S377	P375L	375	Missense	proximal	-2	no	9.016	8.525	EPSD	COSMIC	6.822	Down-regulation
Atypical_PIKK_FRAP_MTOR_ST	O95817	BAG3	P42345	MTOR	T406	A413V	413	Missense	distal	7	no	9.329	10.268	EPSD	COSMIC	6.822	Up-regulation
Atypical_PIKK_FRAP_MTOR_ST	O95817	BAG3	P42345	MTOR	T406	E404K	404	Missense	proximal	-2	no	9.329	9.368	EPSD	COSMIC	6.822	Up-regulation
Atypical_PIKK_FRAP_MTOR_ST	O95817	BAG3	P42345	MTOR	T406	A405T	405	Missense	proximal	-1	no	9.329	9.281	EPSD	COSMIC;GDSC;CCLE	6.822	Down-regulation
Atypical_PIKK_FRAP_MTOR_ST	O95817	BAG3	P42345	MTOR	S560	E553D	553	Missense	distal	-7	no	7.205	7.855	EPSD	COSMIC;GDSC	6.822	Up-regulation
Atypical_PIKK_FRAP_MTOR_ST	O95817	BAG3	P42345	MTOR	S560	S564N	564	Missense	distal	4	no	7.205	6.731	EPSD	COSMIC	6.822	Loss
Atypical_PIKK_FRAP_MTOR_ST	O95817	BAG3	P42345	MTOR	S564	S564N	564	Missense	central	0	yes	12.763	0.000	EPSD	COSMIC	6.822	Loss
Atypical_PIKK_FRAP_MTOR_ST	O95817	BAG3	P42345	MTOR	T568	A574V	574	Missense	distal	6	no	11.720	12.412	EPSD	COSMIC	6.822	Up-regulation
Atypical_PIKK_FRAP_MTOR_ST	O95817	BAG3	P42345	MTOR	T568	S564N	564	Missense	distal	-4	no	11.720	10.589	EPSD	COSMIC	6.822	Down-regulation
Atypical_PIKK_FRAP_MTOR_ST	Q9NQG5	RPRD1B	P42345	MTOR	S164	P162A	162	Missense	proximal	-2	no	8.183	8.388	EPSD	COSMIC	6.822	Up-regulation
Atypical_PIKK_FRAP_MTOR_ST	Q9NQG5	RPRD1B	P42345	MTOR	S164	S166F	166	Missense	proximal	2	no	8.183	6.449	EPSD	COSMIC	6.822	Loss
Atypical_PIKK_FRAP_MTOR_ST	Q9NQG5	RPRD1B	P42345	MTOR	S164	G163S	163	Missense	proximal	-1	no	8.183	8.190	EPSD	COSMIC	6.822	Up-regulation
Atypical_PIKK_FRAP_MTOR_ST	Q9NQG5	RPRD1B	P42345	MTOR	S164	D158N	158	Missense	distal	-6	no	8.183	7.392	EPSD	COSMIC	6.822	Down-regulation
Atypical_PIKK_FRAP_MTOR_ST	Q9NQG5	RPRD1B	P42345	MTOR	S166	P162A	162	Missense	distal	-4	no	12.232	11.397	PhosphoSitePlus	COSMIC	6.822	Down-regulation
Atypical_PIKK_FRAP_MTOR_ST	Q9NQG5	RPRD1B	P42345	MTOR	S166	S166F	166	Missense	central	0	yes	12.232	0.000	PhosphoSitePlus	COSMIC	6.822	Loss
Atypical_PIKK_FRAP_MTOR_ST	Q9NQG5	RPRD1B	P42345	MTOR	S166	G163S	163	Missense	distal	-3	no	12.232	11.860	PhosphoSitePlus	COSMIC	6.822	Down-regulation
Atypical_PIKK_FRAP_MTOR_ST	Q9NQG5	RPRD1B	P42345	MTOR	S166	A172S	172	Missense	distal	6	no	12.232	12.882	PhosphoSitePlus	COSMIC	6.822	Up-regulation
Atypical_PIKK_FRAP_MTOR_ST	Q86TB9	PATL1	P42345	MTOR	S184	R188T	188	Missense	distal	4	no	15.841	16.482	EPSD;PhosphoSitePlus	COSMIC;GDSC;CCLE	6.822	Up-regulation
Atypical_PIKK_FRAP_MTOR_ST	Q86TB9	PATL1	P42345	MTOR	T194	K197I	197	Missense	distal	3	no	11.270	10.436	EPSD	COSMIC	6.822	Down-regulation
Atypical_PIKK_FRAP_MTOR_ST	Q86TB9	PATL1	P42345	MTOR	T194	I192V	192	Missense	proximal	-2	no	11.270	11.791	EPSD	COSMIC	6.822	Up-regulation
Atypical_PIKK_FRAP_MTOR_ST	Q86TB9	PATL1	P42345	MTOR	T194	P195Q	195	Missense	proximal	1	no	11.270	2.656	EPSD	COSMIC	6.822	Loss
Atypical_PIKK_FRAP_MTOR_ST	Q86TB9	PATL1	P42345	MTOR	T194	R188T	188	Missense	distal	-6	no	11.270	11.104	EPSD	COSMIC;GDSC;CCLE	6.822	Down-regulation
Atypical_PIKK_FRAP_MTOR_ST	Q86TB9	PATL1	P42345	MTOR	S233	S233P	233	Missense	central	0	yes	11.026	0.000	EPSD	COSMIC	6.822	Loss
Atypical_PIKK_FRAP_MTOR_ST	Q86TB9	PATL1	P42345	MTOR	S259	A264T	264	Missense	distal	5	no	10.583	9.758	EPSD	COSMIC;GDSC;CCLE	6.822	Down-regulation
Atypical_PIKK_FRAP_MTOR_ST	Q86TB9	PATL1	P42345	MTOR	S259	Q262H	262	Missense	distal	3	no	10.583	12.019	EPSD	COSMIC;GDSC;CCLE	6.822	Up-regulation
Atypical_PIKK_FRAP_MTOR_ST	Q86TB9	PATL1	P42345	MTOR	S278	R284W	284	Missense	distal	6	no	10.419	10.949	EPSD	COSMIC	6.822	Up-regulation
Atypical_PIKK_FRAP_MTOR_ST	Q86TB9	PATL1	P42345	MTOR	S291	R284W	284	Missense	distal	-7	no	10.900	11.360	EPSD	COSMIC	6.822	Up-regulation
Atypical_PIKK_FRAP_MTOR_ST	Q86TB9	PATL1	P42345	MTOR	S546	R551L	551	Missense	distal	5	no	8.237	8.732	EPSD	COSMIC	6.822	Up-regulation
Atypical_PIKK_FRAP_MTOR_ST	Q86TB9	PATL1	P42345	MTOR	S546	S546R	546	Missense	central	0	yes	8.237	0.000	EPSD	COSMIC	6.822	Loss
Atypical_PIKK_FRAP_MTOR_ST	Q86TB9	PATL1	P42345	MTOR	S546	L547V	547	Missense	proximal	1	no	8.237	7.485	EPSD	COSMIC	6.822	Down-regulation
Atypical_PIKK_FRAP_MTOR_ST	Q86TB9	PATL1	P42345	MTOR	S738	A734V	734	Missense	distal	-4	no	11.419	11.699	EPSD	COSMIC	6.822	Up-regulation
Atypical_PIKK_FRAP_MTOR_ST	Q86TB9	PATL1	P42345	MTOR	S738	I739T	739	Missense	proximal	1	no	11.419	10.206	EPSD	COSMIC	6.822	Down-regulation
Atypical_PIKK_FRAP_MTOR_ST	Q13322	GRB10	P42345	MTOR	T23	K19R	19	Missense	distal	-4	no	6.401	6.935	EPSD	COSMIC	6.822	Gain
Atypical_PIKK_FRAP_MTOR_ST	Q13322	GRB10	P42345	MTOR	S68	A69P	69	Missense	proximal	1	no	-1.789	7.094	EPSD	COSMIC	6.822	Gain
Atypical_PIKK_FRAP_MTOR_ST	Q13322	GRB10	P42345	MTOR	S104	R111C	111	Missense	distal	7	no	6.472	6.902	EPSD	COSMIC;CCLE	6.822	Gain
Atypical_PIKK_FRAP_MTOR_ST	Q13322	GRB10	P42345	MTOR	S134	P141S	141	Missense	distal	7	no	10.264	10.243	EPSD	COSMIC	6.822	Down-regulation
Atypical_PIKK_FRAP_MTOR_ST	Q13322	GRB10	P42345	MTOR	S134	S133L	133	Missense	proximal	-1	no	10.264	10.062	EPSD	COSMIC	6.822	Down-regulation
Atypical_PIKK_FRAP_MTOR_ST	Q13322	GRB10	P42345	MTOR	S134	P136L	136	Missense	proximal	2	no	10.264	9.575	EPSD	COSMIC	6.822	Down-regulation
Atypical_PIKK_FRAP_MTOR_ST	Q13322	GRB10	P42345	MTOR	S134	S134F	134	Missense	central	0	yes	10.264	0.000	EPSD	COSMIC	6.822	Loss
Atypical_PIKK_FRAP_MTOR_ST	Q13322	GRB10	P42345	MTOR	S134	P139L	139	Missense	distal	5	no	10.264	11.637	EPSD	COSMIC	6.822	Up-regulation
Atypical_PIKK_FRAP_MTOR_ST	Q13322	GRB10	P42345	MTOR	S150	P156S	156	Missense	distal	6	no	8.664	8.694	EPSD	COSMIC	6.822	Up-regulation
Atypical_PIKK_FRAP_MTOR_ST	Q13322	GRB10	P42345	MTOR	S150	L154F	154	Missense	distal	4	no	8.664	9.060	EPSD	COSMIC	6.822	Up-regulation
Atypical_PIKK_FRAP_MTOR_ST	Q13322	GRB10	P42345	MTOR	S150	P156L	156	Missense	distal	6	no	8.664	7.504	EPSD	COSMIC	6.822	Down-regulation
Atypical_PIKK_FRAP_MTOR_ST	Q13322	GRB10	P42345	MTOR	S150	P151H	151	Missense	proximal	1	no	8.664	-18.527	EPSD	COSMIC	6.822	Loss
Atypical_PIKK_FRAP_MTOR_ST	Q13322	GRB10	P42345	MTOR	S150	P151S	151	Missense	proximal	1	no	8.664	0.140	EPSD	COSMIC	6.822	Loss
Atypical_PIKK_FRAP_MTOR_ST	Q13322	GRB10	P42345	MTOR	T155	P156S	156	Missense	proximal	1	no	10.158	1.634	EPSD;PhosphoSitePlus	COSMIC	6.822	Loss
Atypical_PIKK_FRAP_MTOR_ST	Q13322	GRB10	P42345	MTOR	T155	L154F	154	Missense	proximal	-1	no	10.158	10.176	EPSD;PhosphoSitePlus	COSMIC	6.822	Up-regulation
Atypical_PIKK_FRAP_MTOR_ST	Q13322	GRB10	P42345	MTOR	T155	S158F	158	Missense	distal	3	no	10.158	10.563	EPSD;PhosphoSitePlus	COSMIC	6.822	Up-regulation
Atypical_PIKK_FRAP_MTOR_ST	Q13322	GRB10	P42345	MTOR	T155	P156L	156	Missense	proximal	1	no	10.158	4.189	EPSD;PhosphoSitePlus	COSMIC	6.822	Loss
Atypical_PIKK_FRAP_MTOR_ST	Q13322	GRB10	P42345	MTOR	T155	P151H	151	Missense	distal	-4	no	10.158	9.208	EPSD;PhosphoSitePlus	COSMIC	6.822	Down-regulation
Atypical_PIKK_FRAP_MTOR_ST	Q13322	GRB10	P42345	MTOR	T155	P151S	151	Missense	distal	-4	no	10.158	10.287	EPSD;PhosphoSitePlus	COSMIC	6.822	Up-regulation
Atypical_PIKK_FRAP_MTOR_ST	Q13322	GRB10	P42345	MTOR	S418	L416F	416	Missense	proximal	-2	no	9.602	9.915	EPSD	COSMIC	6.822	Up-regulation
Atypical_PIKK_FRAP_MTOR_ST	Q13322	GRB10	P42345	MTOR	S418	V424L	424	Missense	distal	6	no	9.602	8.372	EPSD	COSMIC	6.822	Down-regulation
Atypical_PIKK_FRAP_MTOR_ST	Q13322	GRB10	P42345	MTOR	S418	A415T	415	Missense	distal	-3	no	9.602	9.656	EPSD	COSMIC	6.822	Up-regulation
Atypical_PIKK_FRAP_MTOR_ST	Q13322	GRB10	P42345	MTOR	S428	V427L	427	Missense	proximal	-1	no	8.085	7.961	PhosphoSitePlus;EPSD	COSMIC	6.822	Down-regulation
Atypical_PIKK_FRAP_MTOR_ST	Q13322	GRB10	P42345	MTOR	S428	V433L	433	Missense	distal	5	no	8.085	8.449	PhosphoSitePlus;EPSD	COSMIC	6.822	Up-regulation
Atypical_PIKK_FRAP_MTOR_ST	Q13322	GRB10	P42345	MTOR	S428	M435I	435	Missense	distal	7	no	8.085	8.319	PhosphoSitePlus;EPSD	COSMIC	6.822	Up-regulation
Atypical_PIKK_FRAP_MTOR_ST	Q13322	GRB10	P42345	MTOR	S428	V424L	424	Missense	distal	-4	no	8.085	8.453	PhosphoSitePlus;EPSD	COSMIC	6.822	Up-regulation
Atypical_PIKK_FRAP_MTOR_ST	Q13322	GRB10	P42345	MTOR	S428	S431F	431	Missense	distal	3	no	8.085	8.489	PhosphoSitePlus;EPSD	COSMIC	6.822	Up-regulation
Atypical_PIKK_FRAP_MTOR_ST	Q13322	GRB10	P42345	MTOR	S428	L432F	432	Missense	distal	4	no	8.085	8.480	PhosphoSitePlus;EPSD	COSMIC	6.822	Up-regulation
Atypical_PIKK_FRAP_MTOR_ST	Q13322	GRB10	P42345	MTOR	S476	L472F	472	Missense	distal	-4	no	11.572	11.911	EPSD;PhosphoSitePlus	COSMIC	6.822	Up-regulation
Atypical_PIKK_FRAP_MTOR_ST	Q13322	GRB10	P42345	MTOR	S476	L478F	478	Missense	proximal	2	no	11.572	10.033	EPSD;PhosphoSitePlus	COSMIC	6.822	Down-regulation
Atypical_PIKK_FRAP_MTOR_ST	Q13322	GRB10	P42345	MTOR	S476	S476N	476	Missense	central	0	yes	11.572	0.000	EPSD;PhosphoSitePlus	COSMIC	6.822	Loss
Atypical_PIKK_FRAP_MTOR_ST	O00141	SGK1	P42345	MTOR	S74	Q81R	81	Missense	distal	7	no	7.397	7.796	EPSD	COSMIC	6.822	Up-regulation
Atypical_PIKK_FRAP_MTOR_ST	O00141	SGK1	P42345	MTOR	S74	N72K	72	Missense	proximal	-2	no	7.397	8.116	EPSD	COSMIC	6.822	Up-regulation
Atypical_PIKK_FRAP_MTOR_ST	O00141	SGK1	P42345	MTOR	S74	S78A	78	Missense	distal	4	no	7.397	6.922	EPSD	COSMIC	6.822	Down-regulation
Atypical_PIKK_FRAP_MTOR_ST	O00141	SGK1	P42345	MTOR	S74	A71T	71	Missense	distal	-3	no	7.397	7.450	EPSD	COSMIC	6.822	Up-regulation
Atypical_PIKK_FRAP_MTOR_ST	O00141	SGK1	P42345	MTOR	S74	P75S	75	Missense	proximal	1	no	7.397	-1.127	EPSD	COSMIC	6.822	Loss
Atypical_PIKK_FRAP_MTOR_ST	O00141	SGK1	P42345	MTOR	S74	N72Y	72	Missense	proximal	-2	no	7.397	7.445	EPSD	COSMIC;CCLE	6.822	Up-regulation
Atypical_PIKK_FRAP_MTOR_ST	O00141	SGK1	P42345	MTOR	S78	Q81R	81	Missense	distal	3	no	9.405	10.671	EPSD	COSMIC	6.822	Up-regulation
Atypical_PIKK_FRAP_MTOR_ST	O00141	SGK1	P42345	MTOR	S78	N72K	72	Missense	distal	-6	no	9.405	9.861	EPSD	COSMIC	6.822	Up-regulation
Atypical_PIKK_FRAP_MTOR_ST	O00141	SGK1	P42345	MTOR	S78	S78A	78	Missense	central	0	yes	9.405	0.000	EPSD	COSMIC	6.822	Loss
Atypical_PIKK_FRAP_MTOR_ST	O00141	SGK1	P42345	MTOR	S78	A71T	71	Missense	distal	-7	no	9.405	10.296	EPSD	COSMIC	6.822	Up-regulation
Atypical_PIKK_FRAP_MTOR_ST	O00141	SGK1	P42345	MTOR	S78	P75S	75	Missense	distal	-3	no	9.405	9.837	EPSD	COSMIC	6.822	Up-regulation
Atypical_PIKK_FRAP_MTOR_ST	O00141	SGK1	P42345	MTOR	S78	N72Y	72	Missense	distal	-6	no	9.405	9.221	EPSD	COSMIC;CCLE	6.822	Down-regulation
Atypical_PIKK_FRAP_MTOR_ST	O00141	SGK1	P42345	MTOR	T260	C258R	258	Missense	proximal	-2	no	8.700	8.423	EPSD	COSMIC	6.822	Down-regulation
Atypical_PIKK_FRAP_MTOR_ST	O00141	SGK1	P42345	MTOR	T260	S255P	255	Missense	distal	-5	no	8.700	8.748	EPSD	COSMIC	6.822	Up-regulation
Atypical_PIKK_FRAP_MTOR_ST	O00141	SGK1	P42345	MTOR	T260	T253N	253	Missense	distal	-7	no	8.700	8.458	EPSD	COSMIC	6.822	Down-regulation
Atypical_PIKK_FRAP_MTOR_ST	O00141	SGK1	P42345	MTOR	S401	V394A	394	Missense	distal	-7	no	11.591	11.479	EPSD	COSMIC	6.822	Down-regulation
Atypical_PIKK_FRAP_MTOR_ST	O00141	SGK1	P42345	MTOR	S422	E416G	416	Missense	distal	-6	no	10.641	10.848	PhosphoSitePlus	COSMIC	6.822	Up-regulation
Atypical_PIKK_FRAP_MTOR_ST	O00141	SGK1	P42345	MTOR	S422	A424S	424	Missense	proximal	2	no	10.641	11.405	PhosphoSitePlus	COSMIC	6.822	Up-regulation
Atypical_PIKK_FRAP_MTOR_ST	O00141	SGK1	P42345	MTOR	S422	T427M	427	Missense	distal	5	no	10.641	10.905	PhosphoSitePlus	COSMIC	6.822	Up-regulation
Atypical_PIKK_FRAP_MTOR_ST	O96018	APBA3	P42345	MTOR	S9	P13L	13	Missense	distal	4	no	9.984	9.600	EPSD	COSMIC	6.822	Down-regulation
Atypical_PIKK_FRAP_MTOR_ST	O96018	APBA3	P42345	MTOR	S9	S7F	7	Missense	proximal	-2	no	9.984	10.163	EPSD	COSMIC	6.822	Up-regulation
Atypical_PIKK_FRAP_MTOR_ST	O96018	APBA3	P42345	MTOR	S372	C376G	376	Missense	distal	4	no	11.258	11.521	EPSD	COSMIC;GDSC	6.822	Up-regulation
Atypical_PIKK_FRAP_MTOR_ST	O96018	APBA3	P42345	MTOR	S372	V367L	367	Missense	distal	-5	no	11.258	11.297	EPSD	COSMIC;GDSC;CCLE	6.822	Up-regulation
Atypical_PIKK_FRAP_MTOR_ST	P31749	AKT1	P42345	MTOR	T92	R86H	86	Missense	distal	-6	no	7.076	6.269	EPSD	COSMIC;GDSC;CCLE	6.822	Loss
Atypical_PIKK_FRAP_MTOR_ST	P31749	AKT1	P42345	MTOR	T92	E97K	97	Missense	distal	5	no	7.076	7.131	EPSD	COSMIC	6.822	Up-regulation
Atypical_PIKK_FRAP_MTOR_ST	P31749	AKT1	P42345	MTOR	T92	E91D	91	Missense	proximal	-1	no	7.076	7.046	EPSD	COSMIC	6.822	Down-regulation
Atypical_PIKK_FRAP_MTOR_ST	P31749	AKT1	P42345	MTOR	T92	E91K	91	Missense	proximal	-1	no	7.076	6.988	EPSD	COSMIC	6.822	Down-regulation
Atypical_PIKK_FRAP_MTOR_ST	P31749	AKT1	P42345	MTOR	T92	W99R	99	Missense	distal	7	no	7.076	7.462	EPSD	COSMIC	6.822	Up-regulation
Atypical_PIKK_FRAP_MTOR_ST	P31749	AKT1	P42345	MTOR	S124	G123D	123	Missense	proximal	-1	no	14.445	14.390	EPSD	COSMIC	6.822	Down-regulation
Atypical_PIKK_FRAP_MTOR_ST	P31749	AKT1	P42345	MTOR	S124	D127N	127	Missense	distal	3	no	14.445	14.576	EPSD	COSMIC	6.822	Up-regulation
Atypical_PIKK_FRAP_MTOR_ST	P31749	AKT1	P42345	MTOR	S124	G130R	130	Missense	distal	6	no	14.445	12.692	EPSD	COSMIC	6.822	Down-regulation
Atypical_PIKK_FRAP_MTOR_ST	P31749	AKT1	P42345	MTOR	T312	M306T	306	Missense	distal	-6	no	10.450	10.379	EPSD	COSMIC	6.822	Down-regulation
Atypical_PIKK_FRAP_MTOR_ST	P31749	AKT1	P42345	MTOR	T312	M306L	306	Missense	distal	-6	no	10.450	9.683	EPSD	COSMIC	6.822	Down-regulation
Atypical_PIKK_FRAP_MTOR_ST	P31749	AKT1	P42345	MTOR	T312	M306I	306	Missense	distal	-6	no	10.450	9.879	EPSD	COSMIC	6.822	Down-regulation
Atypical_PIKK_FRAP_MTOR_ST	P31749	AKT1	P42345	MTOR	T312	T312I	312	Missense	central	0	yes	10.450	0.000	EPSD	COSMIC	6.822	Loss
Atypical_PIKK_FRAP_MTOR_ST	P31749	AKT1	P42345	MTOR	S422	V416M	416	Missense	distal	-6	no	10.195	10.829	EPSD	COSMIC	6.822	Up-regulation
Atypical_PIKK_FRAP_MTOR_ST	P31749	AKT1	P42345	MTOR	S422	S422R	422	Missense	central	0	yes	10.195	0.000	EPSD	COSMIC	6.822	Loss
Atypical_PIKK_FRAP_MTOR_ST	P31749	AKT1	P42345	MTOR	T450	P452L	452	Missense	proximal	2	no	13.470	12.781	EPSD;PhosphoSitePlus	COSMIC	6.822	Down-regulation
Atypical_PIKK_FRAP_MTOR_ST	P31749	AKT1	P42345	MTOR	T450	M446I	446	Missense	distal	-4	no	13.470	13.272	EPSD;PhosphoSitePlus	COSMIC	6.822	Down-regulation
Atypical_PIKK_FRAP_MTOR_ST	P31749	AKT1	P42345	MTOR	T450	I447F	447	Missense	distal	-3	no	13.470	13.107	EPSD;PhosphoSitePlus	COSMIC	6.822	Down-regulation
Atypical_PIKK_FRAP_MTOR_ST	P31749	AKT1	P42345	MTOR	T450	T443M	443	Missense	distal	-7	no	13.470	12.831	EPSD;PhosphoSitePlus	COSMIC	6.822	Down-regulation
Atypical_PIKK_FRAP_MTOR_ST	P31749	AKT1	P42345	MTOR	S473	S477N	477	Missense	distal	4	no	13.336	12.862	PhosphoSitePlus;EPSD	COSMIC	6.822	Down-regulation
Atypical_PIKK_FRAP_MTOR_ST	P31749	AKT1	P42345	MTOR	S473	P470L	470	Missense	distal	-3	no	13.336	14.183	PhosphoSitePlus;EPSD	COSMIC	6.822	Up-regulation
Atypical_PIKK_FRAP_MTOR_ST	P31749	AKT1	P42345	MTOR	S477	S477N	477	Missense	central	0	yes	8.451	0.000	EPSD	COSMIC	6.822	Loss
Atypical_PIKK_FRAP_MTOR_ST	P31749	AKT1	P42345	MTOR	S477	P470L	470	Missense	distal	-7	no	8.451	8.318	EPSD	COSMIC	6.822	Down-regulation
Atypical_PIKK_FRAP_MTOR_ST	Q96F24	NRBF2	P42345	MTOR	S101	H102Y	102	Missense	proximal	1	no	-14.151	8.210	EPSD	COSMIC	6.822	Gain
Atypical_PIKK_FRAP_MTOR_ST	Q96F24	NRBF2	P42345	MTOR	S268	E270G	270	Missense	proximal	2	no	11.864	10.846	EPSD	COSMIC	6.822	Down-regulation
Atypical_PIKK_FRAP_MTOR_ST	Q96F24	NRBF2	P42345	MTOR	S268	E275G	275	Missense	distal	7	no	11.864	12.699	EPSD	COSMIC	6.822	Up-regulation
Atypical_PIKK_FRAP_MTOR_ST	O95163	ELP1	P42345	MTOR	T233	G239E	239	Missense	distal	6	no	8.571	8.810	EPSD	COSMIC;GDSC	6.822	Up-regulation
Atypical_PIKK_FRAP_MTOR_ST	O95163	ELP1	P42345	MTOR	T233	S234N	234	Missense	proximal	1	no	8.571	9.421	EPSD	COSMIC	6.822	Up-regulation
Atypical_PIKK_FRAP_MTOR_ST	O95163	ELP1	P42345	MTOR	T233	T233A	233	Missense	central	0	yes	8.571	0.000	EPSD	COSMIC	6.822	Loss
Atypical_PIKK_FRAP_MTOR_ST	O95163	ELP1	P42345	MTOR	T233	A229V	229	Missense	distal	-4	no	8.571	8.851	EPSD	COSMIC	6.822	Up-regulation
Atypical_PIKK_FRAP_MTOR_ST	O95163	ELP1	P42345	MTOR	S803	S804I	804	Missense	proximal	1	no	5.638	9.104	EPSD	COSMIC	6.822	Gain
Atypical_PIKK_FRAP_MTOR_ST	O95163	ELP1	P42345	MTOR	T935	K938E	938	Missense	distal	3	no	5.528	7.158	EPSD	COSMIC	6.822	Gain
Atypical_PIKK_FRAP_MTOR_ST	O95163	ELP1	P42345	MTOR	S1171	S1176R	1176	Missense	distal	5	no	6.095	7.088	EPSD	COSMIC	6.822	Gain
Atypical_PIKK_FRAP_MTOR_ST	O95163	ELP1	P42345	MTOR	S1211	E1214Q	1214	Missense	distal	3	no	9.826	8.028	EPSD	COSMIC	6.822	Down-regulation
Atypical_PIKK_FRAP_MTOR_ST	O95163	ELP1	P42345	MTOR	S1211	G1210D	1210	Missense	proximal	-1	no	9.826	9.771	EPSD	COSMIC	6.822	Down-regulation
Atypical_PIKK_FRAP_MTOR_ST	Q8NHG8	ZNRF2	P42345	MTOR	S145	P147T	147	Missense	proximal	2	no	9.832	9.278	PhosphoSitePlus	COSMIC	6.822	Down-regulation
Atypical_PIKK_FRAP_MTOR_ST	Q8NHG8	ZNRF2	P42345	MTOR	S151	P147T	147	Missense	distal	-4	no	7.603	7.230	EPSD	COSMIC	6.822	Down-regulation
Atypical_PIKK_FRAP_MTOR_ST	Q96B36	AKT1S1	P42345	MTOR	S88	S92I	92	Missense	distal	4	no	11.772	11.336	EPSD	COSMIC	6.822	Down-regulation
Atypical_PIKK_FRAP_MTOR_ST	Q96B36	AKT1S1	P42345	MTOR	S88	P87S	87	Missense	proximal	-1	no	11.772	11.840	EPSD	COSMIC	6.822	Up-regulation
Atypical_PIKK_FRAP_MTOR_ST	Q96B36	AKT1S1	P42345	MTOR	S88	P82Q	82	Missense	distal	-6	no	11.772	11.595	EPSD	COSMIC	6.822	Down-regulation
Atypical_PIKK_FRAP_MTOR_ST	Q96B36	AKT1S1	P42345	MTOR	S88	P93T	93	Missense	distal	5	no	11.772	11.261	EPSD	COSMIC	6.822	Down-regulation
Atypical_PIKK_FRAP_MTOR_ST	Q96B36	AKT1S1	P42345	MTOR	T90	S92I	92	Missense	proximal	2	no	8.984	8.937	EPSD	COSMIC	6.822	Down-regulation
Atypical_PIKK_FRAP_MTOR_ST	Q96B36	AKT1S1	P42345	MTOR	T90	P87S	87	Missense	distal	-3	no	8.984	9.416	EPSD	COSMIC	6.822	Up-regulation
Atypical_PIKK_FRAP_MTOR_ST	Q96B36	AKT1S1	P42345	MTOR	T90	P93T	93	Missense	distal	3	no	8.984	8.591	EPSD	COSMIC	6.822	Down-regulation
Atypical_PIKK_FRAP_MTOR_ST	Q96B36	AKT1S1	P42345	MTOR	S183	A181T	181	Missense	proximal	-2	no	9.853	9.356	PhosphoSitePlus;EPSD	COSMIC	6.822	Down-regulation
Atypical_PIKK_FRAP_MTOR_ST	Q96B36	AKT1S1	P42345	MTOR	S183	A181V	181	Missense	proximal	-2	no	9.853	9.373	PhosphoSitePlus;EPSD	COSMIC	6.822	Down-regulation
Atypical_PIKK_FRAP_MTOR_ST	Q96B36	AKT1S1	P42345	MTOR	S183	P185H	185	Missense	proximal	2	no	9.853	7.268	PhosphoSitePlus;EPSD	COSMIC	6.822	Down-regulation
Atypical_PIKK_FRAP_MTOR_ST	Q96B36	AKT1S1	P42345	MTOR	S183	V190L	190	Missense	distal	7	no	9.853	10.317	PhosphoSitePlus;EPSD	COSMIC	6.822	Up-regulation
Atypical_PIKK_FRAP_MTOR_ST	Q96B36	AKT1S1	P42345	MTOR	S183	Y180C	180	Missense	distal	-3	no	9.853	9.248	PhosphoSitePlus;EPSD	COSMIC	6.822	Down-regulation
Atypical_PIKK_FRAP_MTOR_ST	Q96B36	AKT1S1	P42345	MTOR	S212	E205K	205	Missense	distal	-7	no	10.377	10.168	EPSD	COSMIC	6.822	Down-regulation
Atypical_PIKK_FRAP_MTOR_ST	Q96B36	AKT1S1	P42345	MTOR	S212	S212L	212	Missense	central	0	yes	10.377	0.000	EPSD	COSMIC	6.822	Loss
Atypical_PIKK_FRAP_MTOR_ST	Q96B36	AKT1S1	P42345	MTOR	S212	A219P	219	Missense	distal	7	no	10.377	10.823	EPSD	COSMIC	6.822	Up-regulation
Atypical_PIKK_FRAP_MTOR_ST	Q96B36	AKT1S1	P42345	MTOR	S212	D214Y	214	Missense	proximal	2	no	10.377	8.783	EPSD	COSMIC	6.822	Down-regulation
Atypical_PIKK_FRAP_MTOR_ST	Q96B36	AKT1S1	P42345	MTOR	S212	P209L	209	Missense	distal	-3	no	10.377	11.224	EPSD	COSMIC	6.822	Up-regulation
Atypical_PIKK_FRAP_MTOR_ST	Q96B36	AKT1S1	P42345	MTOR	S221	R223P	223	Missense	proximal	2	no	6.758	8.965	EPSD;PhosphoSitePlus	COSMIC	6.822	Gain
Atypical_PIKK_FRAP_MTOR_ST	O95747	OXSR1	P42345	MTOR	T185	T178A	178	Missense	distal	-7	no	7.324	6.432	EPSD	COSMIC	6.822	Loss
Atypical_PIKK_FRAP_MTOR_ST	O95747	OXSR1	P42345	MTOR	T185	T189P	189	Missense	distal	4	no	7.324	7.000	EPSD	COSMIC	6.822	Down-regulation
Atypical_PIKK_FRAP_MTOR_ST	O95747	OXSR1	P42345	MTOR	T185	G188V	188	Missense	distal	3	no	7.324	5.300	EPSD	COSMIC	6.822	Loss
Atypical_PIKK_FRAP_MTOR_ST	O95747	OXSR1	P42345	MTOR	S347	A353V	353	Missense	distal	6	no	7.853	8.544	EPSD	COSMIC	6.822	Up-regulation
Atypical_PIKK_FRAP_MTOR_ST	O95747	OXSR1	P42345	MTOR	S359	A353V	353	Missense	distal	-6	no	7.588	7.304	EPSD	COSMIC	6.822	Down-regulation
Atypical_PIKK_FRAP_MTOR_ST	Q9BRS8	LARP6	P42345	MTOR	S228	G222E	222	Missense	distal	-6	no	7.134	6.927	EPSD	COSMIC	6.822	Down-regulation
Atypical_PIKK_FRAP_MTOR_ST	Q9BRS8	LARP6	P42345	MTOR	S348	S348Y	348	Missense	central	0	yes	10.757	0.000	EPSD;PhosphoSitePlus	COSMIC	6.822	Loss
Atypical_PIKK_FRAP_MTOR_ST	Q9BRS8	LARP6	P42345	MTOR	S348	E343K	343	Missense	distal	-5	no	10.757	11.049	EPSD;PhosphoSitePlus	COSMIC	6.822	Up-regulation
Atypical_PIKK_FRAP_MTOR_ST	Q9BRS8	LARP6	P42345	MTOR	S362	Q367L	367	Missense	distal	5	no	12.747	14.049	EPSD	COSMIC	6.822	Up-regulation
Atypical_PIKK_FRAP_MTOR_ST	Q9BRS8	LARP6	P42345	MTOR	S362	A356V	356	Missense	distal	-6	no	12.747	12.463	EPSD	COSMIC;GDSC;CCLE	6.822	Down-regulation
Atypical_PIKK_FRAP_MTOR_ST	Q9BRS8	LARP6	P42345	MTOR	S372	Q367L	367	Missense	distal	-5	no	11.055	10.975	EPSD	COSMIC	6.822	Down-regulation
Atypical_PIKK_FRAP_MTOR_ST	Q9BRS8	LARP6	P42345	MTOR	S372	L371V	371	Missense	proximal	-1	no	11.055	11.178	EPSD	COSMIC	6.822	Up-regulation
Atypical_PIKK_FRAP_MTOR_ST	Q9BRS8	LARP6	P42345	MTOR	S372	T379R	379	Missense	distal	7	no	11.055	12.793	EPSD	COSMIC	6.822	Up-regulation
Atypical_PIKK_FRAP_MTOR_ST	Q9BRS8	LARP6	P42345	MTOR	S376	L371V	371	Missense	distal	-5	no	8.196	8.157	EPSD	COSMIC	6.822	Down-regulation
Atypical_PIKK_FRAP_MTOR_ST	Q9BRS8	LARP6	P42345	MTOR	S376	T379R	379	Missense	distal	3	no	8.196	8.323	EPSD	COSMIC	6.822	Up-regulation
Atypical_PIKK_FRAP_MTOR_ST	Q9BRS8	LARP6	P42345	MTOR	S384	T379R	379	Missense	distal	-5	no	10.186	10.321	EPSD	COSMIC	6.822	Up-regulation
Atypical_PIKK_FRAP_MTOR_ST	Q9BRS8	LARP6	P42345	MTOR	S396	K395M	395	Missense	proximal	-1	no	12.077	12.094	EPSD	COSMIC	6.822	Up-regulation
Atypical_PIKK_FRAP_MTOR_ST	Q9BRS8	LARP6	P42345	MTOR	S396	L398M	398	Missense	proximal	2	no	12.077	10.838	EPSD	COSMIC	6.822	Down-regulation
Atypical_PIKK_FRAP_MTOR_ST	Q9BRS8	LARP6	P42345	MTOR	S409	R414C	414	Missense	distal	5	no	8.698	8.482	PhosphoSitePlus;EPSD	COSMIC;GDSC;CCLE	6.822	Down-regulation
Atypical_PIKK_FRAP_MTOR_ST	Q9BRS8	LARP6	P42345	MTOR	S409	R414H	414	Missense	distal	5	no	8.698	9.003	PhosphoSitePlus;EPSD	COSMIC	6.822	Up-regulation
Atypical_PIKK_FRAP_MTOR_ST	Q9BRS8	LARP6	P42345	MTOR	S409	K415N	415	Missense	distal	6	no	8.698	8.200	PhosphoSitePlus;EPSD	COSMIC	6.822	Down-regulation
Atypical_PIKK_FRAP_MTOR_ST	Q9BRS8	LARP6	P42345	MTOR	S409	L404M	404	Missense	distal	-5	no	8.698	8.715	PhosphoSitePlus;EPSD	COSMIC	6.822	Up-regulation
Atypical_PIKK_FRAP_MTOR_ST	Q9BRS8	LARP6	P42345	MTOR	S409	K415T	415	Missense	distal	6	no	8.698	8.519	PhosphoSitePlus;EPSD	COSMIC	6.822	Down-regulation
Atypical_PIKK_FRAP_MTOR_ST	Q9BRS8	LARP6	P42345	MTOR	S409	E411Q	411	Missense	proximal	2	no	8.698	6.135	PhosphoSitePlus;EPSD	COSMIC	6.822	Loss
Atypical_PIKK_FRAP_MTOR_ST	Q9BRS8	LARP6	P42345	MTOR	S430	R434Q	434	Missense	distal	4	no	7.158	7.290	EPSD	COSMIC	6.822	Up-regulation
Atypical_PIKK_FRAP_MTOR_ST	Q9BRS8	LARP6	P42345	MTOR	S451	G449C	449	Missense	proximal	-2	no	8.920	8.340	EPSD	COSMIC;GDSC;CCLE	6.822	Down-regulation
Atypical_PIKK_FRAP_MTOR_ST	Q9BRS8	LARP6	P42345	MTOR	S451	P448R	448	Missense	distal	-3	no	8.920	9.698	EPSD	COSMIC	6.822	Up-regulation
Atypical_PIKK_FRAP_MTOR_ST	Q9BRS8	LARP6	P42345	MTOR	S451	P448T	448	Missense	distal	-3	no	8.920	8.912	EPSD	COSMIC	6.822	Down-regulation
Atypical_PIKK_FRAP_MTOR_ST	Q9BRS8	LARP6	P42345	MTOR	S451	T450M	450	Missense	proximal	-1	no	8.920	8.871	EPSD	COSMIC	6.822	Down-regulation
Atypical_PIKK_FRAP_MTOR_ST	Q9BRS8	LARP6	P42345	MTOR	S451	R456Q	456	Missense	distal	5	no	8.920	8.113	EPSD	COSMIC	6.822	Down-regulation
Atypical_PIKK_FRAP_MTOR_ST	P26358	DNMT1	P42345	MTOR	S152	S154C	154	Missense	proximal	2	no	8.884	7.338	EPSD	COSMIC	6.822	Down-regulation
Atypical_PIKK_FRAP_MTOR_ST	P26358	DNMT1	P42345	MTOR	S154	S161G	161	Missense	distal	7	no	7.870	8.255	EPSD	COSMIC	6.822	Up-regulation
Atypical_PIKK_FRAP_MTOR_ST	P26358	DNMT1	P42345	MTOR	S154	S154C	154	Missense	central	0	yes	7.870	0.000	EPSD	COSMIC	6.822	Loss
Atypical_PIKK_FRAP_MTOR_ST	P26358	DNMT1	P42345	MTOR	S192	S189L	189	Missense	distal	-3	no	7.769	8.184	EPSD	COSMIC	6.822	Up-regulation
Atypical_PIKK_FRAP_MTOR_ST	P26358	DNMT1	P42345	MTOR	S192	S192F	192	Missense	central	0	yes	7.769	0.000	EPSD	COSMIC	6.822	Loss
Atypical_PIKK_FRAP_MTOR_ST	P26358	DNMT1	P42345	MTOR	T328	R325H	325	Missense	distal	-3	no	7.485	6.738	EPSD	COSMIC	6.822	Loss
Atypical_PIKK_FRAP_MTOR_ST	P26358	DNMT1	P42345	MTOR	T328	R325L	325	Missense	distal	-3	no	7.485	7.554	EPSD	COSMIC	6.822	Up-regulation
Atypical_PIKK_FRAP_MTOR_ST	P26358	DNMT1	P42345	MTOR	T328	P332L	332	Missense	distal	4	no	7.485	7.101	EPSD	COSMIC	6.822	Down-regulation
Atypical_PIKK_FRAP_MTOR_ST	P26358	DNMT1	P42345	MTOR	T328	E321G	321	Missense	distal	-7	no	7.485	7.327	EPSD	COSMIC	6.822	Down-regulation
Atypical_PIKK_FRAP_MTOR_ST	P26358	DNMT1	P42345	MTOR	S387	N383D	383	Missense	distal	-4	no	4.702	6.862	EPSD	COSMIC	6.822	Gain
Atypical_PIKK_FRAP_MTOR_ST	P26358	DNMT1	P42345	MTOR	S714	P710S	710	Missense	distal	-4	no	10.634	10.763	PhosphoSitePlus	COSMIC	6.822	Up-regulation
Atypical_PIKK_FRAP_MTOR_ST	P26358	DNMT1	P42345	MTOR	S714	M712T	712	Missense	proximal	-2	no	10.634	11.222	PhosphoSitePlus	COSMIC;GDSC	6.822	Up-regulation
Atypical_PIKK_FRAP_MTOR_ST	P26358	DNMT1	P42345	MTOR	S714	M712L	712	Missense	proximal	-2	no	10.634	11.024	PhosphoSitePlus	COSMIC	6.822	Up-regulation
Atypical_PIKK_FRAP_MTOR_ST	P26358	DNMT1	P42345	MTOR	S878	P879S	879	Missense	proximal	1	no	15.630	7.106	EPSD	COSMIC;CCLE	6.822	Down-regulation
Atypical_PIKK_FRAP_MTOR_ST	P26358	DNMT1	P42345	MTOR	S878	E877K	877	Missense	proximal	-1	no	15.630	15.542	EPSD	COSMIC	6.822	Down-regulation
Atypical_PIKK_FRAP_MTOR_ST	P26358	DNMT1	P42345	MTOR	S878	T882I	882	Missense	distal	4	no	15.630	15.127	EPSD	COSMIC	6.822	Down-regulation
Atypical_PIKK_FRAP_MTOR_ST	P26358	DNMT1	P42345	MTOR	S919	R920L	920	Missense	proximal	1	no	3.635	7.499	EPSD	COSMIC	6.822	Gain
Atypical_PIKK_FRAP_MTOR_ST	P26358	DNMT1	P42345	MTOR	S954	R958C	958	Missense	distal	4	no	7.059	6.846	EPSD	COSMIC	6.822	Down-regulation
Atypical_PIKK_FRAP_MTOR_ST	P26358	DNMT1	P42345	MTOR	S954	P955L	955	Missense	proximal	1	no	7.059	1.090	EPSD	COSMIC	6.822	Loss
Atypical_PIKK_FRAP_MTOR_ST	P26358	DNMT1	P42345	MTOR	S954	K961N	961	Missense	distal	7	no	7.059	8.011	EPSD	COSMIC	6.822	Up-regulation
Atypical_PIKK_FRAP_MTOR_ST	P26358	DNMT1	P42345	MTOR	S954	R960Q	960	Missense	distal	6	no	7.059	7.443	EPSD	COSMIC	6.822	Up-regulation
Atypical_PIKK_FRAP_MTOR_ST	P26358	DNMT1	P42345	MTOR	S954	K951R	951	Missense	distal	-3	no	7.059	7.773	EPSD	COSMIC	6.822	Up-regulation
Atypical_PIKK_FRAP_MTOR_ST	P26358	DNMT1	P42345	MTOR	S954	R958H	958	Missense	distal	4	no	7.059	6.799	EPSD	COSMIC	6.822	Loss
Atypical_PIKK_FRAP_MTOR_ST	P26358	DNMT1	P42345	MTOR	S954	P959S	959	Missense	distal	5	no	7.059	6.945	EPSD	COSMIC	6.822	Down-regulation
Atypical_PIKK_FRAP_MTOR_ST	P26358	DNMT1	P42345	MTOR	S954	T947M	947	Missense	distal	-7	no	7.059	6.420	EPSD	COSMIC	6.822	Loss
Atypical_PIKK_FRAP_MTOR_ST	P26358	DNMT1	P42345	MTOR	S954	I950M	950	Missense	distal	-4	no	7.059	7.257	EPSD	COSMIC	6.822	Up-regulation
Atypical_PIKK_FRAP_MTOR_ST	P26358	DNMT1	P42345	MTOR	S1105	N1101K	1101	Missense	distal	-4	no	15.842	16.555	EPSD	COSMIC	6.822	Up-regulation
Atypical_PIKK_FRAP_MTOR_ST	P26358	DNMT1	P42345	MTOR	S1105	D1098V	1098	Missense	distal	-7	no	15.842	14.869	EPSD	COSMIC	6.822	Down-regulation
Atypical_PIKK_FRAP_MTOR_ST	P26358	DNMT1	P42345	MTOR	S1105	R1104C	1104	Missense	proximal	-1	no	15.842	16.015	EPSD	COSMIC	6.822	Up-regulation
Atypical_PIKK_FRAP_MTOR_ST	P26358	DNMT1	P42345	MTOR	S1105	P1106L	1106	Missense	proximal	1	no	15.842	9.873	EPSD	COSMIC	6.822	Down-regulation
Atypical_PIKK_FRAP_MTOR_ST	P26358	DNMT1	P42345	MTOR	S1122	Q1123P	1123	Missense	proximal	1	no	-1.528	7.086	EPSD	COSMIC	6.822	Gain
Atypical_PIKK_FRAP_MTOR_ST	P01106	MYC	P42345	MTOR	T58	P63L	63	Missense	distal	5	no	5.619	6.993	EPSD	COSMIC	6.822	Gain
Atypical_PIKK_FRAP_MTOR_ST	P01106	MYC	P42345	MTOR	S62	P57S	57	Missense	distal	-5	no	13.333	13.285	PhosphoSitePlus	COSMIC;CCLE	6.822	Down-regulation
Atypical_PIKK_FRAP_MTOR_ST	P01106	MYC	P42345	MTOR	S62	S62P	62	Missense	central	0	yes	13.333	0.000	PhosphoSitePlus	COSMIC;CCLE	6.822	Loss
Atypical_PIKK_FRAP_MTOR_ST	P01106	MYC	P42345	MTOR	S62	P59L	59	Missense	distal	-3	no	13.333	14.180	PhosphoSitePlus	COSMIC;CCLE	6.822	Up-regulation
Atypical_PIKK_FRAP_MTOR_ST	P01106	MYC	P42345	MTOR	S62	T58N	58	Missense	distal	-4	no	13.333	12.704	PhosphoSitePlus	COSMIC;CCLE	6.822	Down-regulation
Atypical_PIKK_FRAP_MTOR_ST	P01106	MYC	P42345	MTOR	S62	P60H	60	Missense	proximal	-2	no	13.333	12.619	PhosphoSitePlus	COSMIC;CCLE	6.822	Down-regulation
Atypical_PIKK_FRAP_MTOR_ST	P01106	MYC	P42345	MTOR	S62	P63L	63	Missense	proximal	1	no	13.333	7.364	PhosphoSitePlus	COSMIC	6.822	Down-regulation
Atypical_PIKK_FRAP_MTOR_ST	P01106	MYC	P42345	MTOR	S62	P63H	63	Missense	proximal	1	no	13.333	-13.858	PhosphoSitePlus	COSMIC	6.822	Loss
Atypical_PIKK_FRAP_MTOR_ST	P01106	MYC	P42345	MTOR	S62	T58A	58	Missense	distal	-4	no	13.333	12.872	PhosphoSitePlus	COSMIC;CCLE	6.822	Down-regulation
Atypical_PIKK_FRAP_MTOR_ST	P01106	MYC	P42345	MTOR	S62	P59A	59	Missense	distal	-3	no	13.333	13.272	PhosphoSitePlus	COSMIC;CCLE	6.822	Down-regulation
Atypical_PIKK_FRAP_MTOR_ST	P01106	MYC	P42345	MTOR	S62	P59R	59	Missense	distal	-3	no	13.333	14.111	PhosphoSitePlus	COSMIC	6.822	Up-regulation
Atypical_PIKK_FRAP_MTOR_ST	P01106	MYC	P42345	MTOR	S62	P60A	60	Missense	proximal	-2	no	13.333	13.538	PhosphoSitePlus	COSMIC;CCLE	6.822	Up-regulation
Atypical_PIKK_FRAP_MTOR_ST	P01106	MYC	P42345	MTOR	S62	P57T	57	Missense	distal	-5	no	13.333	13.292	PhosphoSitePlus	COSMIC;CCLE	6.822	Down-regulation
Atypical_PIKK_FRAP_MTOR_ST	P01106	MYC	P42345	MTOR	S62	P59S	59	Missense	distal	-3	no	13.333	13.765	PhosphoSitePlus	COSMIC;CCLE	6.822	Up-regulation
Atypical_PIKK_FRAP_MTOR_ST	P01106	MYC	P42345	MTOR	S62	S62F	62	Missense	central	0	yes	13.333	0.000	PhosphoSitePlus	COSMIC	6.822	Loss
Atypical_PIKK_FRAP_MTOR_ST	P01106	MYC	P42345	MTOR	S62	T58I	58	Missense	distal	-4	no	13.333	12.910	PhosphoSitePlus	COSMIC;CCLE	6.822	Down-regulation
Atypical_PIKK_FRAP_MTOR_ST	P01106	MYC	P42345	MTOR	S62	T58P	58	Missense	distal	-4	no	13.333	13.706	PhosphoSitePlus	COSMIC	6.822	Up-regulation
Atypical_PIKK_FRAP_MTOR_ST	P01106	MYC	P42345	MTOR	S62	S64R	64	Missense	proximal	2	no	13.333	11.621	PhosphoSitePlus	COSMIC;CCLE	6.822	Down-regulation
Atypical_PIKK_FRAP_MTOR_ST	P01106	MYC	P42345	MTOR	S62	P57L	57	Missense	distal	-5	no	13.333	13.261	PhosphoSitePlus	COSMIC;CCLE	6.822	Down-regulation
Atypical_PIKK_FRAP_MTOR_ST	P01106	MYC	P42345	MTOR	S62	P63S	63	Missense	proximal	1	no	13.333	4.809	PhosphoSitePlus	COSMIC;CCLE	6.822	Loss
Atypical_PIKK_FRAP_MTOR_ST	P01106	MYC	P42345	MTOR	S62	R66H	66	Missense	distal	4	no	13.333	13.074	PhosphoSitePlus	COSMIC	6.822	Down-regulation
Atypical_PIKK_FRAP_MTOR_ST	P01106	MYC	P42345	MTOR	S62	P57F	57	Missense	distal	-5	no	13.333	13.292	PhosphoSitePlus	COSMIC	6.822	Down-regulation
Atypical_PIKK_FRAP_MTOR_ST	P01106	MYC	P42345	MTOR	S62	P59Q	59	Missense	distal	-3	no	13.333	13.503	PhosphoSitePlus	COSMIC;CCLE	6.822	Up-regulation
Atypical_PIKK_FRAP_MTOR_ST	P01106	MYC	P42345	MTOR	S62	P59T	59	Missense	distal	-3	no	13.333	13.326	PhosphoSitePlus	COSMIC	6.822	Down-regulation
Atypical_PIKK_FRAP_MTOR_ST	P01106	MYC	P42345	MTOR	S62	P60S	60	Missense	proximal	-2	no	13.333	12.977	PhosphoSitePlus	COSMIC	6.822	Down-regulation
Atypical_PIKK_FRAP_MTOR_ST	P01106	MYC	P42345	MTOR	S62	P63A	63	Missense	proximal	1	no	13.333	4.450	PhosphoSitePlus	COSMIC	6.822	Loss
Atypical_PIKK_FRAP_MTOR_ST	P01106	MYC	P42345	MTOR	S62	S64N	64	Missense	proximal	2	no	13.333	11.932	PhosphoSitePlus	COSMIC	6.822	Down-regulation
Atypical_PIKK_FRAP_MTOR_ST	P01106	MYC	P42345	MTOR	S62	P60L	60	Missense	proximal	-2	no	13.333	12.843	PhosphoSitePlus	COSMIC	6.822	Down-regulation
Atypical_PIKK_FRAP_MTOR_ST	P01106	MYC	P42345	MTOR	S62	P57A	57	Missense	distal	-5	no	13.333	13.312	PhosphoSitePlus	COSMIC	6.822	Down-regulation
Atypical_PIKK_FRAP_MTOR_ST	P01106	MYC	P42345	MTOR	S62	L56V	56	Missense	distal	-6	no	13.333	13.466	PhosphoSitePlus	COSMIC	6.822	Up-regulation
Atypical_PIKK_FRAP_MTOR_ST	P01106	MYC	P42345	MTOR	S62	P63R	63	Missense	proximal	1	no	13.333	3.500	PhosphoSitePlus	COSMIC	6.822	Loss
Atypical_PIKK_FRAP_MTOR_ST	P01106	MYC	P42345	MTOR	S62	L56M	56	Missense	distal	-6	no	13.333	14.099	PhosphoSitePlus	COSMIC	6.822	Up-regulation
Atypical_PIKK_FRAP_MTOR_ST	P01106	MYC	P42345	MTOR	S62	L69V	69	Missense	distal	7	no	13.333	12.869	PhosphoSitePlus	COSMIC	6.822	Down-regulation
Atypical_PIKK_FRAP_MTOR_ST	P01106	MYC	P42345	MTOR	S62	P63T	63	Missense	proximal	1	no	13.333	7.061	PhosphoSitePlus	COSMIC	6.822	Down-regulation
Atypical_PIKK_FRAP_MTOR_ST	P01106	MYC	P42345	MTOR	S62	S67F	67	Missense	distal	5	no	13.333	13.920	PhosphoSitePlus	COSMIC	6.822	Up-regulation
Atypical_PIKK_FRAP_MTOR_ST	P01106	MYC	P42345	MTOR	S62	S62A	62	Missense	central	0	yes	13.333	0.000	PhosphoSitePlus	COSMIC	6.822	Loss
Atypical_PIKK_FRAP_MTOR_ST	P01106	MYC	P42345	MTOR	S62	P57R	57	Missense	distal	-5	no	13.333	13.427	PhosphoSitePlus	COSMIC	6.822	Up-regulation
Atypical_PIKK_FRAP_MTOR_ST	P01106	MYC	P42345	MTOR	S62	L69P	69	Missense	distal	7	no	13.333	12.377	PhosphoSitePlus	COSMIC	6.822	Down-regulation
Atypical_PIKK_FRAP_MTOR_ST	P01106	MYC	P42345	MTOR	S62	P60T	60	Missense	proximal	-2	no	13.333	13.041	PhosphoSitePlus	COSMIC;CCLE	6.822	Down-regulation
Atypical_PIKK_FRAP_MTOR_ST	P01106	MYC	P42345	MTOR	S62	L69F	69	Missense	distal	7	no	13.333	12.937	PhosphoSitePlus	COSMIC	6.822	Down-regulation
Atypical_PIKK_FRAP_MTOR_ST	P01106	MYC	P42345	MTOR	S62	S64T	64	Missense	proximal	2	no	13.333	13.274	PhosphoSitePlus	COSMIC	6.822	Down-regulation
Atypical_PIKK_FRAP_MTOR_ST	P01106	MYC	P42345	MTOR	S62	R65C	65	Missense	distal	3	no	13.333	10.846	PhosphoSitePlus	COSMIC	6.822	Down-regulation
Atypical_PIKK_FRAP_MTOR_ST	P01106	MYC	P42345	MTOR	S62	L55P	55	Missense	distal	-7	no	13.333	13.466	PhosphoSitePlus	COSMIC	6.822	Up-regulation
Atypical_PIKK_FRAP_MTOR_ST	P01106	MYC	P42345	MTOR	S62	L55M	55	Missense	distal	-7	no	13.333	13.315	PhosphoSitePlus	COSMIC	6.822	Down-regulation
Atypical_PIKK_FRAP_MTOR_ST	P01106	MYC	P42345	MTOR	S71	A76V	76	Missense	distal	5	no	6.308	7.001	EPSD	COSMIC	6.822	Gain
Atypical_PIKK_FRAP_MTOR_ST	P01106	MYC	P42345	MTOR	S71	Y74N	74	Missense	distal	3	no	6.308	6.905	EPSD	COSMIC;CCLE	6.822	Gain
Atypical_PIKK_FRAP_MTOR_ST	P01106	MYC	P42345	MTOR	S71	Y74H	74	Missense	distal	3	no	6.308	7.338	EPSD	COSMIC	6.822	Gain
Atypical_PIKK_FRAP_MTOR_ST	P01106	MYC	P42345	MTOR	T78	S81F	81	Missense	distal	3	no	7.759	8.163	EPSD	COSMIC;CCLE	6.822	Up-regulation
Atypical_PIKK_FRAP_MTOR_ST	P01106	MYC	P42345	MTOR	T78	R83Q	83	Missense	distal	5	no	7.759	6.951	EPSD	COSMIC	6.822	Down-regulation
Atypical_PIKK_FRAP_MTOR_ST	P01106	MYC	P42345	MTOR	T78	A76V	76	Missense	proximal	-2	no	7.759	7.279	EPSD	COSMIC	6.822	Down-regulation
Atypical_PIKK_FRAP_MTOR_ST	P01106	MYC	P42345	MTOR	T78	V77I	77	Missense	proximal	-1	no	7.759	7.601	EPSD	COSMIC;CCLE	6.822	Down-regulation
Atypical_PIKK_FRAP_MTOR_ST	P01106	MYC	P42345	MTOR	T78	S71L	71	Missense	distal	-7	no	7.759	7.189	EPSD	COSMIC	6.822	Down-regulation
Atypical_PIKK_FRAP_MTOR_ST	P01106	MYC	P42345	MTOR	T78	L82V	82	Missense	distal	4	no	7.759	8.086	EPSD	COSMIC	6.822	Up-regulation
Atypical_PIKK_FRAP_MTOR_ST	P01106	MYC	P42345	MTOR	T78	G84R	84	Missense	distal	6	no	7.759	6.006	EPSD	COSMIC	6.822	Loss
Atypical_PIKK_FRAP_MTOR_ST	P01106	MYC	P42345	MTOR	T78	P79S	79	Missense	proximal	1	no	7.759	-0.765	EPSD	COSMIC	6.822	Loss
Atypical_PIKK_FRAP_MTOR_ST	P01106	MYC	P42345	MTOR	T78	Y74N	74	Missense	distal	-4	no	7.759	7.258	EPSD	COSMIC;CCLE	6.822	Down-regulation
Atypical_PIKK_FRAP_MTOR_ST	P01106	MYC	P42345	MTOR	T78	F80L	80	Missense	proximal	2	no	7.759	9.298	EPSD	COSMIC	6.822	Up-regulation
Atypical_PIKK_FRAP_MTOR_ST	P01106	MYC	P42345	MTOR	T78	D85Y	85	Missense	distal	7	no	7.759	6.798	EPSD	COSMIC	6.822	Loss
Atypical_PIKK_FRAP_MTOR_ST	P01106	MYC	P42345	MTOR	T78	V77G	77	Missense	proximal	-1	no	7.759	7.830	EPSD	COSMIC	6.822	Up-regulation
Atypical_PIKK_FRAP_MTOR_ST	P01106	MYC	P42345	MTOR	T78	S81C	81	Missense	distal	3	no	7.759	4.992	EPSD	COSMIC	6.822	Loss
Atypical_PIKK_FRAP_MTOR_ST	P01106	MYC	P42345	MTOR	T78	Y74H	74	Missense	distal	-4	no	7.759	7.310	EPSD	COSMIC	6.822	Down-regulation
Atypical_PIKK_FRAP_MTOR_ST	P01106	MYC	P42345	MTOR	T78	D85E	85	Missense	distal	7	no	7.759	6.747	EPSD	COSMIC	6.822	Loss
Atypical_PIKK_FRAP_MTOR_ST	P01106	MYC	P42345	MTOR	T78	V75I	75	Missense	distal	-3	no	7.759	8.058	EPSD	COSMIC	6.822	Up-regulation
Atypical_PIKK_FRAP_MTOR_ST	P01106	MYC	P42345	MTOR	T78	S71W	71	Missense	distal	-7	no	7.759	7.460	EPSD	COSMIC	6.822	Down-regulation
Atypical_PIKK_FRAP_MTOR_ST	P01106	MYC	P42345	MTOR	T78	L82H	82	Missense	distal	4	no	7.759	7.566	EPSD	COSMIC	6.822	Down-regulation
Atypical_PIKK_FRAP_MTOR_ST	P01106	MYC	P42345	MTOR	T78	S73P	73	Missense	distal	-5	no	7.759	7.807	EPSD	COSMIC	6.822	Up-regulation
Atypical_PIKK_FRAP_MTOR_ST	P01106	MYC	P42345	MTOR	T78	P72F	72	Missense	distal	-6	no	7.759	7.263	EPSD	COSMIC	6.822	Down-regulation
Atypical_PIKK_FRAP_MTOR_ST	P01106	MYC	P42345	MTOR	T78	P72R	72	Missense	distal	-6	no	7.759	7.846	EPSD	COSMIC	6.822	Up-regulation
Atypical_PIKK_FRAP_MTOR_ST	P01106	MYC	P42345	MTOR	S161	K157T	157	Missense	distal	-4	no	8.230	8.147	EPSD	COSMIC	6.822	Down-regulation
Atypical_PIKK_FRAP_MTOR_ST	P01106	MYC	P42345	MTOR	S161	A155S	155	Missense	distal	-6	no	8.230	8.568	EPSD	COSMIC	6.822	Up-regulation
Atypical_PIKK_FRAP_MTOR_ST	P01106	MYC	P42345	MTOR	S161	K157N	157	Missense	distal	-4	no	8.230	7.518	EPSD	COSMIC	6.822	Down-regulation
Atypical_PIKK_FRAP_MTOR_ST	P01106	MYC	P42345	MTOR	S161	A155T	155	Missense	distal	-6	no	8.230	8.509	EPSD	COSMIC	6.822	Up-regulation
Atypical_PIKK_FRAP_MTOR_ST	P01106	MYC	P42345	MTOR	S161	N163K	163	Missense	proximal	2	no	8.230	9.565	EPSD	COSMIC	6.822	Up-regulation
Atypical_PIKK_FRAP_MTOR_ST	P01106	MYC	P42345	MTOR	S161	P162R	162	Missense	proximal	1	no	8.230	-1.603	EPSD	COSMIC	6.822	Loss
Atypical_PIKK_FRAP_MTOR_ST	P01106	MYC	P42345	MTOR	S161	A154T	154	Missense	distal	-7	no	8.230	9.121	EPSD	COSMIC	6.822	Up-regulation
Atypical_PIKK_FRAP_MTOR_ST	P01106	MYC	P42345	MTOR	S161	G160D	160	Missense	proximal	-1	no	8.230	8.175	EPSD	COSMIC	6.822	Down-regulation
Atypical_PIKK_FRAP_MTOR_ST	P01106	MYC	P42345	MTOR	S161	S159N	159	Missense	proximal	-2	no	8.230	7.639	EPSD	COSMIC	6.822	Down-regulation
Atypical_PIKK_FRAP_MTOR_ST	P01106	MYC	P42345	MTOR	S161	A165S	165	Missense	distal	4	no	8.230	8.704	EPSD	COSMIC	6.822	Up-regulation
Atypical_PIKK_FRAP_MTOR_ST	P01106	MYC	P42345	MTOR	S161	A165T	165	Missense	distal	4	no	8.230	8.772	EPSD	COSMIC	6.822	Up-regulation
Atypical_PIKK_FRAP_MTOR_ST	P01106	MYC	P42345	MTOR	S161	S159T	159	Missense	proximal	-2	no	8.230	8.294	EPSD	COSMIC	6.822	Up-regulation
Atypical_PIKK_FRAP_MTOR_ST	P01106	MYC	P42345	MTOR	S161	D158G	158	Missense	distal	-3	no	8.230	8.477	EPSD	COSMIC	6.822	Up-regulation
Atypical_PIKK_FRAP_MTOR_ST	P01106	MYC	P42345	MTOR	S161	R166H	166	Missense	distal	5	no	8.230	8.535	EPSD	COSMIC	6.822	Up-regulation
Atypical_PIKK_FRAP_MTOR_ST	P01106	MYC	P42345	MTOR	S161	S161N	161	Missense	central	0	yes	8.230	0.000	EPSD	COSMIC	6.822	Loss
Atypical_PIKK_FRAP_MTOR_ST	P01106	MYC	P42345	MTOR	S161	R156G	156	Missense	distal	-5	no	8.230	8.156	EPSD	COSMIC	6.822	Down-regulation
Atypical_PIKK_FRAP_MTOR_ST	P01106	MYC	P42345	MTOR	S161	A154G	154	Missense	distal	-7	no	8.230	8.508	EPSD	COSMIC	6.822	Up-regulation
Atypical_PIKK_FRAP_MTOR_ST	P01106	MYC	P42345	MTOR	S161	S159R	159	Missense	proximal	-2	no	8.230	8.102	EPSD	COSMIC	6.822	Down-regulation
Atypical_PIKK_FRAP_MTOR_ST	P01106	MYC	P42345	MTOR	S161	A165D	165	Missense	distal	4	no	8.230	8.634	EPSD	COSMIC	6.822	Up-regulation
Atypical_PIKK_FRAP_MTOR_ST	P01106	MYC	P42345	MTOR	S169	C171S	171	Missense	proximal	2	no	6.057	7.604	EPSD	COSMIC	6.822	Gain
Atypical_PIKK_FRAP_MTOR_ST	P01106	MYC	P42345	MTOR	S169	A165S	165	Missense	distal	-4	no	6.057	7.020	EPSD	COSMIC	6.822	Gain
Atypical_PIKK_FRAP_MTOR_ST	P01106	MYC	P42345	MTOR	S169	V170I	170	Missense	proximal	1	no	6.057	7.720	EPSD	COSMIC	6.822	Gain
Atypical_PIKK_FRAP_MTOR_ST	P01106	MYC	P42345	MTOR	S169	S174Y	174	Missense	distal	5	no	6.057	6.922	EPSD	COSMIC	6.822	Gain
Atypical_PIKK_FRAP_MTOR_ST	P01106	MYC	P42345	MTOR	S169	A165D	165	Missense	distal	-4	no	6.057	8.049	EPSD	COSMIC	6.822	Gain
Atypical_PIKK_FRAP_MTOR_ST	P01106	MYC	P42345	MTOR	S169	S174N	174	Missense	distal	5	no	6.057	7.539	EPSD	COSMIC	6.822	Gain
Atypical_PIKK_FRAP_MTOR_ST	P01106	MYC	P42345	MTOR	S169	S174R	174	Missense	distal	5	no	6.057	7.049	EPSD	COSMIC	6.822	Gain
Atypical_PIKK_FRAP_MTOR_ST	P01106	MYC	P42345	MTOR	S204	P198S	198	Missense	distal	-6	no	7.797	7.777	EPSD	COSMIC	6.822	Down-regulation
Atypical_PIKK_FRAP_MTOR_ST	P01106	MYC	P42345	MTOR	S204	S203R	203	Missense	proximal	-1	no	7.797	7.635	EPSD	COSMIC	6.822	Down-regulation
Atypical_PIKK_FRAP_MTOR_ST	P01106	MYC	P42345	MTOR	S204	S203N	203	Missense	proximal	-1	no	7.797	7.616	EPSD	COSMIC;CCLE	6.822	Down-regulation
Atypical_PIKK_FRAP_MTOR_ST	P01106	MYC	P42345	MTOR	S204	Y197D	197	Missense	distal	-7	no	7.797	8.130	EPSD	COSMIC	6.822	Up-regulation
Atypical_PIKK_FRAP_MTOR_ST	P01106	MYC	P42345	MTOR	S204	S203T	203	Missense	proximal	-1	no	7.797	7.743	EPSD	COSMIC	6.822	Down-regulation
Atypical_PIKK_FRAP_MTOR_ST	P01106	MYC	P42345	MTOR	S204	S203I	203	Missense	proximal	-1	no	7.797	7.561	EPSD	COSMIC	6.822	Down-regulation
Atypical_PIKK_FRAP_MTOR_ST	P01106	MYC	P42345	MTOR	S204	Q211R	211	Missense	distal	7	no	7.797	8.197	EPSD	COSMIC	6.822	Up-regulation
Atypical_PIKK_FRAP_MTOR_ST	P01106	MYC	P42345	MTOR	S204	P205S	205	Missense	proximal	1	no	7.797	-0.727	EPSD	COSMIC	6.822	Loss
Atypical_PIKK_FRAP_MTOR_ST	P01106	MYC	P42345	MTOR	S204	N200I	200	Missense	distal	-4	no	7.797	8.003	EPSD	COSMIC	6.822	Up-regulation
Atypical_PIKK_FRAP_MTOR_ST	P01106	MYC	P42345	MTOR	S204	S204A	204	Missense	central	0	yes	7.797	0.000	EPSD	COSMIC	6.822	Loss
Atypical_PIKK_FRAP_MTOR_ST	P01106	MYC	P42345	MTOR	S204	S202T	202	Missense	proximal	-2	no	7.797	7.861	EPSD	COSMIC	6.822	Up-regulation
Atypical_PIKK_FRAP_MTOR_ST	P01106	MYC	P42345	MTOR	S204	S207P	207	Missense	distal	3	no	7.797	7.783	EPSD	COSMIC	6.822	Down-regulation
Atypical_PIKK_FRAP_MTOR_ST	P01106	MYC	P42345	MTOR	S281	S283F	283	Missense	proximal	2	no	10.727	8.993	EPSD	COSMIC	6.822	Down-regulation
Atypical_PIKK_FRAP_MTOR_ST	P01106	MYC	P42345	MTOR	S281	S277L	277	Missense	distal	-4	no	10.727	10.412	EPSD	COSMIC	6.822	Down-regulation
Atypical_PIKK_FRAP_MTOR_ST	P01106	MYC	P42345	MTOR	S281	H287Q	287	Missense	distal	6	no	10.727	10.795	EPSD	COSMIC	6.822	Up-regulation
Atypical_PIKK_FRAP_MTOR_ST	P01106	MYC	P42345	MTOR	S281	S279C	279	Missense	proximal	-2	no	10.727	10.877	EPSD	COSMIC	6.822	Up-regulation
Atypical_PIKK_FRAP_MTOR_ST	P01106	MYC	P42345	MTOR	S281	S283Y	283	Missense	proximal	2	no	10.727	8.990	EPSD	COSMIC	6.822	Down-regulation
Atypical_PIKK_FRAP_MTOR_ST	P01106	MYC	P42345	MTOR	S281	P282A	282	Missense	proximal	1	no	10.727	1.844	EPSD	COSMIC	6.822	Loss
Atypical_PIKK_FRAP_MTOR_ST	P01106	MYC	P42345	MTOR	S281	G285E	285	Missense	distal	4	no	10.727	11.018	EPSD	COSMIC	6.822	Up-regulation
Atypical_PIKK_FRAP_MTOR_ST	P01106	MYC	P42345	MTOR	S281	G280R	280	Missense	proximal	-1	no	10.727	10.572	EPSD	COSMIC	6.822	Down-regulation
Atypical_PIKK_FRAP_MTOR_ST	P01106	MYC	P42345	MTOR	S281	G274D	274	Missense	distal	-7	no	10.727	11.534	EPSD	COSMIC	6.822	Up-regulation
Atypical_PIKK_FRAP_MTOR_ST	P01106	MYC	P42345	MTOR	S281	S281F	281	Missense	central	0	yes	10.727	0.000	EPSD	COSMIC	6.822	Loss
Atypical_PIKK_FRAP_MTOR_ST	P01106	MYC	P42345	MTOR	S293	V296F	296	Missense	distal	3	no	6.053	7.414	EPSD	COSMIC	6.822	Gain
Atypical_PIKK_FRAP_MTOR_ST	P01106	MYC	P42345	MTOR	S344	S347F	347	Missense	distal	3	no	11.935	12.339	EPSD	COSMIC	6.822	Up-regulation
Atypical_PIKK_FRAP_MTOR_ST	P01106	MYC	P42345	MTOR	S344	E351K	351	Missense	distal	7	no	11.935	12.031	EPSD	COSMIC	6.822	Up-regulation
Atypical_PIKK_FRAP_MTOR_ST	P01106	MYC	P42345	MTOR	S344	S337T	337	Missense	distal	-7	no	11.935	11.986	EPSD	COSMIC	6.822	Up-regulation
Atypical_PIKK_FRAP_MTOR_ST	Q9BPZ7	MAPKAP1	P42345	MTOR	S84	T86K	86	Missense	proximal	2	no	8.791	8.784	EPSD	COSMIC	6.822	Down-regulation
Atypical_PIKK_FRAP_MTOR_ST	Q9BPZ7	MAPKAP1	P42345	MTOR	S84	E91K	91	Missense	distal	7	no	8.791	8.888	EPSD	COSMIC	6.822	Up-regulation
Atypical_PIKK_FRAP_MTOR_ST	Q9BPZ7	MAPKAP1	P42345	MTOR	S84	R82K	82	Missense	proximal	-2	no	8.791	9.047	EPSD	COSMIC	6.822	Up-regulation
Atypical_PIKK_FRAP_MTOR_ST	Q9BPZ7	MAPKAP1	P42345	MTOR	S140	R145H	145	Missense	distal	5	no	6.641	6.946	EPSD	COSMIC	6.822	Gain
Atypical_PIKK_FRAP_MTOR_ST	Q9BPZ7	MAPKAP1	P42345	MTOR	S270	E277K	277	Missense	distal	7	no	9.225	9.321	EPSD	COSMIC	6.822	Up-regulation
Atypical_PIKK_FRAP_MTOR_ST	Q9Y6W6	DUSP10	P42345	MTOR	S224	R219K	219	Missense	distal	-5	no	9.530	9.375	EPSD;PhosphoSitePlus	COSMIC	6.822	Down-regulation
Atypical_PIKK_FRAP_MTOR_ST	Q8TBX8	PIP4K2C	P42345	MTOR	S324	G323S	323	Missense	proximal	-1	no	10.254	10.261	EPSD;PhosphoSitePlus	COSMIC	6.822	Up-regulation
Atypical_PIKK_FRAP_MTOR_ST	Q8TBX8	PIP4K2C	P42345	MTOR	S328	G323S	323	Missense	distal	-5	no	10.768	10.701	PhosphoSitePlus;EPSD	COSMIC	6.822	Down-regulation
Atypical_PIKK_FRAP_MTOR_ST	Q9C0C7	AMBRA1	P42345	MTOR	S52	R46K	46	Missense	distal	-6	no	12.532	12.194	PhosphoSitePlus	COSMIC	6.822	Down-regulation
Atypical_PIKK_FRAP_MTOR_ST	Q9C0C7	AMBRA1	P42345	MTOR	S52	R54H	54	Missense	proximal	2	no	12.532	12.154	PhosphoSitePlus	COSMIC	6.822	Down-regulation
Atypical_PIKK_FRAP_MTOR_ST	Q9C0C7	AMBRA1	P42345	MTOR	S52	K45N	45	Missense	distal	-7	no	12.532	12.955	PhosphoSitePlus	COSMIC	6.822	Up-regulation
Atypical_PIKK_FRAP_MTOR_ST	Q9C0C7	AMBRA1	P42345	MTOR	S52	R54C	54	Missense	proximal	2	no	12.532	12.698	PhosphoSitePlus	COSMIC	6.822	Up-regulation
Atypical_PIKK_FRAP_MTOR_ST	Q9C0C7	AMBRA1	P42345	MTOR	S52	L58V	58	Missense	distal	6	no	12.532	13.762	PhosphoSitePlus	COSMIC	6.822	Up-regulation
Atypical_PIKK_FRAP_MTOR_ST	Q9C0C7	AMBRA1	P42345	MTOR	S269	P274L	274	Missense	distal	5	no	7.706	9.079	EPSD	COSMIC	6.822	Up-regulation
Atypical_PIKK_FRAP_MTOR_ST	Q9C0C7	AMBRA1	P42345	MTOR	S443	S444L	444	Missense	proximal	1	no	6.326	8.881	EPSD	COSMIC	6.822	Gain
Atypical_PIKK_FRAP_MTOR_ST	Q9C0C7	AMBRA1	P42345	MTOR	S443	S444W	444	Missense	proximal	1	no	6.326	7.299	EPSD	COSMIC	6.822	Gain
Atypical_PIKK_FRAP_MTOR_ST	Q9C0C7	AMBRA1	P42345	MTOR	T626	E623K	623	Missense	distal	-3	no	7.233	7.238	EPSD	COSMIC	6.822	Up-regulation
Atypical_PIKK_FRAP_MTOR_ST	Q9C0C7	AMBRA1	P42345	MTOR	S636	P640S	640	Missense	distal	4	no	6.832	7.087	EPSD	COSMIC	6.822	Up-regulation
Atypical_PIKK_FRAP_MTOR_ST	Q9C0C7	AMBRA1	P42345	MTOR	S636	P640L	640	Missense	distal	4	no	6.832	6.447	EPSD	COSMIC	6.822	Loss
Atypical_PIKK_FRAP_MTOR_ST	Q9C0C7	AMBRA1	P42345	MTOR	S636	E642K	642	Missense	distal	6	no	6.832	5.927	EPSD	COSMIC	6.822	Loss
Atypical_PIKK_FRAP_MTOR_ST	Q9C0C7	AMBRA1	P42345	MTOR	S722	R720S	720	Missense	proximal	-2	no	14.275	14.403	EPSD	COSMIC	6.822	Up-regulation
Atypical_PIKK_FRAP_MTOR_ST	Q9C0C7	AMBRA1	P42345	MTOR	S722	A719V	719	Missense	distal	-3	no	14.275	14.905	EPSD	COSMIC	6.822	Up-regulation
Atypical_PIKK_FRAP_MTOR_ST	Q9C0C7	AMBRA1	P42345	MTOR	S722	A728T	728	Missense	distal	6	no	14.275	14.012	EPSD	COSMIC	6.822	Down-regulation
Atypical_PIKK_FRAP_MTOR_ST	Q9C0C7	AMBRA1	P42345	MTOR	S800	R795Q	795	Missense	distal	-5	no	10.220	10.135	EPSD	COSMIC	6.822	Down-regulation
Atypical_PIKK_FRAP_MTOR_ST	Q9C0C7	AMBRA1	P42345	MTOR	S800	R795W	795	Missense	distal	-5	no	10.220	10.278	EPSD	COSMIC	6.822	Up-regulation
Atypical_PIKK_FRAP_MTOR_ST	Q9C0C7	AMBRA1	P42345	MTOR	S800	R807M	807	Missense	distal	7	no	10.220	9.568	EPSD	COSMIC	6.822	Down-regulation
Atypical_PIKK_FRAP_MTOR_ST	Q9C0C7	AMBRA1	P42345	MTOR	S800	R803H	803	Missense	distal	3	no	10.220	10.390	EPSD	COSMIC	6.822	Up-regulation
Atypical_PIKK_FRAP_MTOR_ST	Q9C0C7	AMBRA1	P42345	MTOR	S1209	R1212W	1212	Missense	distal	3	no	7.017	5.257	EPSD	COSMIC	6.822	Loss
Atypical_PIKK_FRAP_MTOR_ST	Q9C0C7	AMBRA1	P42345	MTOR	S1209	R1212Q	1212	Missense	distal	3	no	7.017	5.751	EPSD	COSMIC	6.822	Loss
Atypical_PIKK_FRAP_MTOR_ST	Q9C0C7	AMBRA1	P42345	MTOR	S1209	T1203N	1203	Missense	distal	-6	no	7.017	6.389	EPSD	COSMIC	6.822	Loss
Atypical_PIKK_FRAP_MTOR_ST	Q9C0C7	AMBRA1	P42345	MTOR	S1209	S1204F	1204	Missense	distal	-5	no	7.017	7.024	EPSD	COSMIC	6.822	Up-regulation
Atypical_PIKK_FRAP_MTOR_ST	Q9C0C7	AMBRA1	P42345	MTOR	S1209	Q1207R	1207	Missense	proximal	-2	no	7.017	6.677	EPSD	COSMIC	6.822	Loss
Atypical_PIKK_FRAP_MTOR_ST	Q9C0C7	AMBRA1	P42345	MTOR	T1238	R1241W	1241	Missense	distal	3	no	9.247	7.488	EPSD	COSMIC	6.822	Down-regulation
Atypical_PIKK_FRAP_MTOR_ST	Q9C0C7	AMBRA1	P42345	MTOR	T1238	W1233C	1233	Missense	distal	-5	no	9.247	9.314	EPSD	COSMIC	6.822	Up-regulation
Atypical_PIKK_FRAP_MTOR_ST	Q9C0C7	AMBRA1	P42345	MTOR	T1238	R1241Q	1241	Missense	distal	3	no	9.247	7.981	EPSD	COSMIC	6.822	Down-regulation
Atypical_PIKK_FRAP_MTOR_ST	Q9C0C7	AMBRA1	P42345	MTOR	T1238	A1231P	1231	Missense	distal	-7	no	9.247	9.651	EPSD	COSMIC	6.822	Up-regulation
Atypical_PIKK_FRAP_MTOR_ST	Q00613	HSF1	P42345	MTOR	S123	D129G	129	Missense	distal	6	no	12.025	12.239	EPSD	COSMIC	6.822	Up-regulation
Atypical_PIKK_FRAP_MTOR_ST	Q00613	HSF1	P42345	MTOR	S123	T120A	120	Missense	distal	-3	no	12.025	11.972	EPSD	COSMIC	6.822	Down-regulation
Atypical_PIKK_FRAP_MTOR_ST	Q00613	HSF1	P42345	MTOR	S136	D129G	129	Missense	distal	-7	no	11.475	10.668	EPSD	COSMIC	6.822	Down-regulation
Atypical_PIKK_FRAP_MTOR_ST	Q00613	HSF1	P42345	MTOR	S136	R133S	133	Missense	distal	-3	no	11.475	11.129	EPSD	COSMIC	6.822	Down-regulation
Atypical_PIKK_FRAP_MTOR_ST	Q00613	HSF1	P42345	MTOR	S136	V137I	137	Missense	proximal	1	no	11.475	13.138	EPSD	COSMIC	6.822	Up-regulation
Atypical_PIKK_FRAP_MTOR_ST	Q00613	HSF1	P42345	MTOR	S136	K139N	139	Missense	distal	3	no	11.475	12.310	EPSD	COSMIC;GDSC;CCLE	6.822	Up-regulation
Atypical_PIKK_FRAP_MTOR_ST	Q00613	HSF1	P42345	MTOR	S244	S237L	237	Missense	distal	-7	no	9.770	9.200	EPSD	COSMIC	6.822	Down-regulation
Atypical_PIKK_FRAP_MTOR_ST	Q00613	HSF1	P42345	MTOR	S244	P239H	239	Missense	distal	-5	no	9.770	9.868	EPSD	COSMIC	6.822	Up-regulation
Atypical_PIKK_FRAP_MTOR_ST	Q00613	HSF1	P42345	MTOR	S244	S244F	244	Missense	central	0	yes	9.770	0.000	EPSD	COSMIC	6.822	Loss
Atypical_PIKK_FRAP_MTOR_ST	Q00613	HSF1	P42345	MTOR	S275	S279F	279	Missense	distal	4	no	8.306	8.062	EPSD	COSMIC	6.822	Down-regulation
Atypical_PIKK_FRAP_MTOR_ST	Q00613	HSF1	P42345	MTOR	S275	P280L	280	Missense	distal	5	no	8.306	9.679	EPSD	COSMIC	6.822	Up-regulation
Atypical_PIKK_FRAP_MTOR_ST	Q00613	HSF1	P42345	MTOR	S275	I268V	268	Missense	distal	-7	no	8.306	8.583	EPSD	COSMIC	6.822	Up-regulation
Atypical_PIKK_FRAP_MTOR_ST	Q00613	HSF1	P42345	MTOR	S275	G281S	281	Missense	distal	6	no	8.306	8.375	EPSD	COSMIC	6.822	Up-regulation
Atypical_PIKK_FRAP_MTOR_ST	Q00613	HSF1	P42345	MTOR	S279	S279F	279	Missense	central	0	yes	10.095	0.000	EPSD	COSMIC	6.822	Loss
Atypical_PIKK_FRAP_MTOR_ST	Q00613	HSF1	P42345	MTOR	S279	P280L	280	Missense	proximal	1	no	10.095	4.126	EPSD	COSMIC	6.822	Loss
Atypical_PIKK_FRAP_MTOR_ST	Q00613	HSF1	P42345	MTOR	S279	G281S	281	Missense	proximal	2	no	10.095	10.275	EPSD	COSMIC	6.822	Up-regulation
Atypical_PIKK_FRAP_MTOR_ST	Q00613	HSF1	P42345	MTOR	S279	S283N	283	Missense	distal	4	no	10.095	9.621	EPSD	COSMIC	6.822	Down-regulation
Atypical_PIKK_FRAP_MTOR_ST	Q00613	HSF1	P42345	MTOR	S292	R287K	287	Missense	distal	-5	no	10.886	10.730	EPSD	COSMIC	6.822	Down-regulation
Atypical_PIKK_FRAP_MTOR_ST	Q00613	HSF1	P42345	MTOR	S307	S303G	303	Missense	distal	-4	no	9.596	9.029	EPSD	COSMIC	6.822	Down-regulation
Atypical_PIKK_FRAP_MTOR_ST	Q00613	HSF1	P42345	MTOR	S307	P304L	304	Missense	distal	-3	no	9.596	10.444	EPSD	COSMIC;GDSC	6.822	Up-regulation
Atypical_PIKK_FRAP_MTOR_ST	Q00613	HSF1	P42345	MTOR	S307	R309G	309	Missense	proximal	2	no	9.596	11.130	EPSD	COSMIC	6.822	Up-regulation
Atypical_PIKK_FRAP_MTOR_ST	Q00613	HSF1	P42345	MTOR	S314	R309G	309	Missense	distal	-5	no	13.184	13.110	EPSD	COSMIC	6.822	Down-regulation
Atypical_PIKK_FRAP_MTOR_ST	Q00613	HSF1	P42345	MTOR	S314	P318T	318	Missense	distal	4	no	13.184	13.508	EPSD	COSMIC	6.822	Up-regulation
Atypical_PIKK_FRAP_MTOR_ST	Q00613	HSF1	P42345	MTOR	S320	P327Q	327	Missense	distal	7	no	6.766	7.138	EPSD	COSMIC	6.822	Gain
Atypical_PIKK_FRAP_MTOR_ST	Q00613	HSF1	P42345	MTOR	S326	L330V	330	Missense	distal	4	no	11.446	11.773	PhosphoSitePlus	COSMIC	6.822	Up-regulation
Atypical_PIKK_FRAP_MTOR_ST	Q00613	HSF1	P42345	MTOR	S326	P327Q	327	Missense	proximal	1	no	11.446	2.832	PhosphoSitePlus	COSMIC	6.822	Loss
Atypical_PIKK_FRAP_MTOR_ST	Q00613	HSF1	P42345	MTOR	S363	S363P	363	Missense	central	0	yes	8.232	0.000	EPSD	COSMIC	6.822	Loss
Atypical_PIKK_FRAP_MTOR_ST	Q00613	HSF1	P42345	MTOR	S363	P365Q	365	Missense	proximal	2	no	8.232	6.013	EPSD	COSMIC	6.822	Loss
Atypical_PIKK_FRAP_MTOR_ST	Q00613	HSF1	P42345	MTOR	S363	D356N	356	Missense	distal	-7	no	8.232	7.796	EPSD	COSMIC	6.822	Down-regulation
Atypical_PIKK_FRAP_MTOR_ST	Q00613	HSF1	P42345	MTOR	S363	P365T	365	Missense	proximal	2	no	8.232	7.678	EPSD	COSMIC	6.822	Down-regulation
Atypical_PIKK_FRAP_MTOR_ST	Q00613	HSF1	P42345	MTOR	S363	E358K	358	Missense	distal	-5	no	8.232	8.524	EPSD	COSMIC	6.822	Up-regulation
Atypical_PIKK_FRAP_MTOR_ST	Q00613	HSF1	P42345	MTOR	S363	P365L	365	Missense	proximal	2	no	8.232	7.542	EPSD	COSMIC	6.822	Down-regulation
Atypical_PIKK_FRAP_MTOR_ST	Q00613	HSF1	P42345	MTOR	T369	S363P	363	Missense	distal	-6	no	14.012	14.032	EPSD	COSMIC	6.822	Up-regulation
Atypical_PIKK_FRAP_MTOR_ST	Q00613	HSF1	P42345	MTOR	T369	P365Q	365	Missense	distal	-4	no	14.012	13.758	EPSD	COSMIC	6.822	Down-regulation
Atypical_PIKK_FRAP_MTOR_ST	Q00613	HSF1	P42345	MTOR	T369	P365T	365	Missense	distal	-4	no	14.012	13.639	EPSD	COSMIC	6.822	Down-regulation
Atypical_PIKK_FRAP_MTOR_ST	Q00613	HSF1	P42345	MTOR	T369	L374F	374	Missense	distal	5	no	14.012	13.112	EPSD	COSMIC	6.822	Down-regulation
Atypical_PIKK_FRAP_MTOR_ST	Q00613	HSF1	P42345	MTOR	T369	P365L	365	Missense	distal	-4	no	14.012	13.826	EPSD	COSMIC	6.822	Down-regulation
Atypical_PIKK_FRAP_MTOR_ST	Q00613	HSF1	P42345	MTOR	S419	L417Q	417	Missense	proximal	-2	no	14.113	14.459	EPSD	COSMIC	6.822	Up-regulation
Atypical_PIKK_FRAP_MTOR_ST	Q00613	HSF1	P42345	MTOR	S419	V422M	422	Missense	distal	3	no	14.113	12.689	EPSD	COSMIC	6.822	Down-regulation
Atypical_PIKK_FRAP_MTOR_ST	Q00613	HSF1	P42345	MTOR	S419	S419N	419	Missense	central	0	yes	14.113	0.000	EPSD	COSMIC	6.822	Loss
Atypical_PIKK_FRAP_MTOR_ST	Q00613	HSF1	P42345	MTOR	S513	E519K	519	Missense	distal	6	no	9.925	9.020	EPSD	COSMIC	6.822	Down-regulation
Atypical_PIKK_FRAP_MTOR_ST	Q00613	HSF1	P42345	MTOR	S518	E519K	519	Missense	proximal	1	no	8.096	5.348	EPSD	COSMIC	6.822	Loss
Atypical_PIKK_FRAP_MTOR_ST	Q5T4S7	UBR4	P42345	MTOR	S178	A177S	177	Missense	proximal	-1	no	11.189	11.195	EPSD	COSMIC	6.822	Up-regulation
Atypical_PIKK_FRAP_MTOR_ST	Q5T4S7	UBR4	P42345	MTOR	S246	L247P	247	Missense	proximal	1	no	2.842	8.811	EPSD	COSMIC	6.822	Gain
Atypical_PIKK_FRAP_MTOR_ST	Q5T4S7	UBR4	P42345	MTOR	S372	K366T	366	Missense	distal	-6	no	10.830	11.001	EPSD	COSMIC	6.822	Up-regulation
Atypical_PIKK_FRAP_MTOR_ST	Q5T4S7	UBR4	P42345	MTOR	S457	V455L	455	Missense	proximal	-2	no	7.396	7.179	EPSD	COSMIC	6.822	Down-regulation
Atypical_PIKK_FRAP_MTOR_ST	Q5T4S7	UBR4	P42345	MTOR	S457	S457F	457	Missense	central	0	yes	7.396	0.000	EPSD	COSMIC	6.822	Loss
Atypical_PIKK_FRAP_MTOR_ST	Q5T4S7	UBR4	P42345	MTOR	S457	R450C	450	Missense	distal	-7	no	7.396	6.301	EPSD	COSMIC	6.822	Loss
Atypical_PIKK_FRAP_MTOR_ST	Q5T4S7	UBR4	P42345	MTOR	S457	G461E	461	Missense	distal	4	no	7.396	7.687	EPSD	COSMIC	6.822	Up-regulation
Atypical_PIKK_FRAP_MTOR_ST	Q5T4S7	UBR4	P42345	MTOR	S555	G554D	554	Missense	proximal	-1	no	8.973	8.918	EPSD	COSMIC	6.822	Down-regulation
Atypical_PIKK_FRAP_MTOR_ST	Q5T4S7	UBR4	P42345	MTOR	S555	S555F	555	Missense	central	0	yes	8.973	0.000	EPSD	COSMIC	6.822	Loss
Atypical_PIKK_FRAP_MTOR_ST	Q5T4S7	UBR4	P42345	MTOR	S620	P616S	616	Missense	distal	-4	no	8.757	8.886	EPSD	COSMIC	6.822	Up-regulation
Atypical_PIKK_FRAP_MTOR_ST	Q5T4S7	UBR4	P42345	MTOR	S620	P615H	615	Missense	distal	-5	no	8.757	8.855	EPSD	COSMIC	6.822	Up-regulation
Atypical_PIKK_FRAP_MTOR_ST	Q5T4S7	UBR4	P42345	MTOR	T905	A903T	903	Missense	proximal	-2	no	8.373	7.876	EPSD	COSMIC	6.822	Down-regulation
Atypical_PIKK_FRAP_MTOR_ST	Q5T4S7	UBR4	P42345	MTOR	T905	L907F	907	Missense	proximal	2	no	8.373	6.834	EPSD	COSMIC	6.822	Down-regulation
Atypical_PIKK_FRAP_MTOR_ST	Q5T4S7	UBR4	P42345	MTOR	S1331	L1334V	1334	Missense	distal	3	no	5.812	7.125	EPSD	COSMIC	6.822	Gain
Atypical_PIKK_FRAP_MTOR_ST	Q5T4S7	UBR4	P42345	MTOR	S1652	S1647F	1647	Missense	distal	-5	no	6.917	6.924	EPSD	COSMIC	6.822	Up-regulation
Atypical_PIKK_FRAP_MTOR_ST	Q5T4S7	UBR4	P42345	MTOR	S1652	Q1648K	1648	Missense	distal	-4	no	6.917	6.880	EPSD	COSMIC	6.822	Down-regulation
Atypical_PIKK_FRAP_MTOR_ST	Q5T4S7	UBR4	P42345	MTOR	T1731	G1735D	1735	Missense	distal	4	no	8.291	8.743	EPSD	COSMIC	6.822	Up-regulation
Atypical_PIKK_FRAP_MTOR_ST	Q5T4S7	UBR4	P42345	MTOR	S1762	S1760G	1760	Missense	proximal	-2	no	7.527	8.256	EPSD	COSMIC	6.822	Up-regulation
Atypical_PIKK_FRAP_MTOR_ST	Q5T4S7	UBR4	P42345	MTOR	T2140	L2144F	2144	Missense	distal	4	no	6.518	6.914	EPSD	COSMIC	6.822	Gain
Atypical_PIKK_FRAP_MTOR_ST	Q5T4S7	UBR4	P42345	MTOR	S2719	R2721Q	2721	Missense	proximal	2	no	8.123	8.111	EPSD	COSMIC	6.822	Down-regulation
Atypical_PIKK_FRAP_MTOR_ST	Q5T4S7	UBR4	P42345	MTOR	S2719	R2712S	2712	Missense	distal	-7	no	8.123	8.882	EPSD	COSMIC	6.822	Up-regulation
Atypical_PIKK_FRAP_MTOR_ST	Q5T4S7	UBR4	P42345	MTOR	S2722	R2721Q	2721	Missense	proximal	-1	no	8.810	8.829	EPSD	COSMIC	6.822	Up-regulation
Atypical_PIKK_FRAP_MTOR_ST	Q5T4S7	UBR4	P42345	MTOR	T2724	R2721Q	2721	Missense	distal	-3	no	9.580	8.971	EPSD	COSMIC	6.822	Down-regulation
Atypical_PIKK_FRAP_MTOR_ST	Q5T4S7	UBR4	P42345	MTOR	S2788	A2795S	2795	Missense	distal	7	no	11.301	11.726	EPSD	COSMIC	6.822	Up-regulation
Atypical_PIKK_FRAP_MTOR_ST	Q5T4S7	UBR4	P42345	MTOR	S2788	P2787L	2787	Missense	proximal	-1	no	11.301	11.167	EPSD	COSMIC	6.822	Down-regulation
Atypical_PIKK_FRAP_MTOR_ST	Q5T4S7	UBR4	P42345	MTOR	S2852	S2849N	2849	Missense	distal	-3	no	6.621	7.170	EPSD	COSMIC	6.822	Gain
Atypical_PIKK_FRAP_MTOR_ST	Q5T4S7	UBR4	P42345	MTOR	S2885	R2883W	2883	Missense	proximal	-2	no	8.612	8.313	EPSD	COSMIC	6.822	Down-regulation
Atypical_PIKK_FRAP_MTOR_ST	Q5T4S7	UBR4	P42345	MTOR	S2885	P2886S	2886	Missense	proximal	1	no	8.612	0.088	EPSD	COSMIC	6.822	Loss
Atypical_PIKK_FRAP_MTOR_ST	Q5T4S7	UBR4	P42345	MTOR	S2885	H2889R	2889	Missense	distal	4	no	8.612	8.871	EPSD	COSMIC	6.822	Up-regulation
Atypical_PIKK_FRAP_MTOR_ST	Q5T4S7	UBR4	P42345	MTOR	S2885	S2880I	2880	Missense	distal	-5	no	8.612	8.677	EPSD	COSMIC	6.822	Up-regulation
Atypical_PIKK_FRAP_MTOR_ST	Q5T4S7	UBR4	P42345	MTOR	S2885	D2878E	2878	Missense	distal	-7	no	8.612	7.963	EPSD	COSMIC	6.822	Down-regulation
Atypical_PIKK_FRAP_MTOR_ST	Q5T4S7	UBR4	P42345	MTOR	S3254	T3257A	3257	Missense	distal	3	no	6.678	8.140	EPSD	COSMIC	6.822	Gain
Atypical_PIKK_FRAP_MTOR_ST	Q5T4S7	UBR4	P42345	MTOR	S3271	M3273I	3273	Missense	proximal	2	no	6.728	8.115	EPSD	COSMIC	6.822	Gain
Atypical_PIKK_FRAP_MTOR_ST	Q5T4S7	UBR4	P42345	MTOR	S3316	E3313D	3313	Missense	distal	-3	no	11.730	12.229	EPSD	COSMIC;GDSC;CCLE	6.822	Up-regulation
Atypical_PIKK_FRAP_MTOR_ST	Q5T4S7	UBR4	P42345	MTOR	T4116	S4117P	4117	Missense	proximal	1	no	6.572	15.096	EPSD	COSMIC	6.822	Gain
Atypical_PIKK_FRAP_MTOR_ST	Q5T4S7	UBR4	P42345	MTOR	S4117	R4115T	4115	Missense	proximal	-2	no	11.895	12.087	EPSD	COSMIC	6.822	Up-regulation
Atypical_PIKK_FRAP_MTOR_ST	Q5T4S7	UBR4	P42345	MTOR	S4117	P4118S	4118	Missense	proximal	1	no	11.895	3.371	EPSD	COSMIC	6.822	Loss
Atypical_PIKK_FRAP_MTOR_ST	Q5T4S7	UBR4	P42345	MTOR	S4117	S4117P	4117	Missense	central	0	yes	11.895	0.000	EPSD	COSMIC	6.822	Loss
Atypical_PIKK_FRAP_MTOR_ST	Q5T4S7	UBR4	P42345	MTOR	S4513	K4517N	4517	Missense	distal	4	no	8.875	8.672	EPSD	COSMIC	6.822	Down-regulation
Atypical_PIKK_FRAP_MTOR_ST	Q5T4S7	UBR4	P42345	MTOR	S4973	G4980W	4980	Missense	distal	7	no	7.913	7.935	EPSD	COSMIC	6.822	Up-regulation
Atypical_PIKK_FRAP_MTOR_ST	Q5T4S7	UBR4	P42345	MTOR	S4973	S4975N	4975	Missense	proximal	2	no	7.913	6.511	EPSD	COSMIC;GDSC;CCLE	6.822	Loss
Atypical_PIKK_FRAP_MTOR_ST	Q5T4S7	UBR4	P42345	MTOR	S5066	Q5067L	5067	Missense	proximal	1	no	4.807	7.452	EPSD	COSMIC	6.822	Gain
Atypical_PIKK_FRAP_MTOR_ST	Q9H5H4	ZNF768	P42345	MTOR	S23	P24T	24	Missense	proximal	1	no	11.283	5.011	EPSD	COSMIC;CCLE	6.822	Loss
Atypical_PIKK_FRAP_MTOR_ST	Q9H5H4	ZNF768	P42345	MTOR	S76	E82K	82	Missense	distal	6	no	7.904	7.000	EPSD	COSMIC	6.822	Down-regulation
Atypical_PIKK_FRAP_MTOR_ST	Q9H5H4	ZNF768	P42345	MTOR	S83	E82K	82	Missense	proximal	-1	no	11.657	11.569	EPSD	COSMIC	6.822	Down-regulation
Atypical_PIKK_FRAP_MTOR_ST	Q9H5H4	ZNF768	P42345	MTOR	S83	R89G	89	Missense	distal	6	no	11.657	13.409	EPSD	COSMIC	6.822	Up-regulation
Atypical_PIKK_FRAP_MTOR_ST	Q9H5H4	ZNF768	P42345	MTOR	S90	R89G	89	Missense	proximal	-1	no	9.700	9.855	EPSD	COSMIC	6.822	Up-regulation
Atypical_PIKK_FRAP_MTOR_ST	Q9H5H4	ZNF768	P42345	MTOR	S90	P96S	96	Missense	distal	6	no	9.700	9.730	EPSD	COSMIC	6.822	Up-regulation
Atypical_PIKK_FRAP_MTOR_ST	Q9H5H4	ZNF768	P42345	MTOR	S90	L93I	93	Missense	distal	3	no	9.700	9.757	EPSD	COSMIC	6.822	Up-regulation
Atypical_PIKK_FRAP_MTOR_ST	Q9H5H4	ZNF768	P42345	MTOR	S97	P96S	96	Missense	proximal	-1	no	11.915	11.983	EPSD	COSMIC	6.822	Up-regulation
Atypical_PIKK_FRAP_MTOR_ST	Q9H5H4	ZNF768	P42345	MTOR	S97	L93I	93	Missense	distal	-4	no	11.915	11.304	EPSD	COSMIC	6.822	Down-regulation
Atypical_PIKK_FRAP_MTOR_ST	Q9H5H4	ZNF768	P42345	MTOR	S125	R120G	120	Missense	distal	-5	no	6.898	6.824	EPSD	COSMIC;GDSC	6.822	Down-regulation
Atypical_PIKK_FRAP_MTOR_ST	Q9H5H4	ZNF768	P42345	MTOR	S132	R138Q	138	Missense	distal	6	no	9.467	9.851	EPSD	COSMIC	6.822	Up-regulation
Atypical_PIKK_FRAP_MTOR_ST	Q9H5H4	ZNF768	P42345	MTOR	S139	R138Q	138	Missense	proximal	-1	no	10.411	10.430	PhosphoSitePlus	COSMIC	6.822	Up-regulation
Atypical_PIKK_FRAP_MTOR_ST	Q9H5H4	ZNF768	P42345	MTOR	S274	Q280L	280	Missense	distal	6	no	9.588	9.837	EPSD	COSMIC	6.822	Up-regulation
Atypical_PIKK_FRAP_MTOR_ST	Q9H5H4	ZNF768	P42345	MTOR	S274	I277L	277	Missense	distal	3	no	9.588	9.531	EPSD	COSMIC	6.822	Down-regulation
Atypical_PIKK_FRAP_MTOR_ST	Q9H5H4	ZNF768	P42345	MTOR	S274	S274P	274	Missense	central	0	yes	9.588	0.000	EPSD	COSMIC	6.822	Loss
Atypical_PIKK_FRAP_MTOR_ST	Q9H5H4	ZNF768	P42345	MTOR	S274	R281C	281	Missense	distal	7	no	9.588	10.018	EPSD	COSMIC	6.822	Up-regulation
Atypical_PIKK_FRAP_MTOR_ST	Q9H5H4	ZNF768	P42345	MTOR	S414	S411F	411	Missense	distal	-3	no	9.072	9.143	EPSD	COSMIC	6.822	Up-regulation
Atypical_PIKK_FRAP_MTOR_ST	Q9H5H4	ZNF768	P42345	MTOR	S414	R413W	413	Missense	proximal	-1	no	9.072	9.144	EPSD	COSMIC	6.822	Up-regulation
Atypical_PIKK_FRAP_MTOR_ST	Q9H5H4	ZNF768	P42345	MTOR	S414	A420V	420	Missense	distal	6	no	9.072	9.764	EPSD	COSMIC	6.822	Up-regulation
Atypical_PIKK_FRAP_MTOR_ST	Q9H5H4	ZNF768	P42345	MTOR	S442	R437S	437	Missense	distal	-5	no	14.328	14.187	EPSD	COSMIC	6.822	Down-regulation
Atypical_PIKK_FRAP_MTOR_ST	Q9H5H4	ZNF768	P42345	MTOR	S442	A448T	448	Missense	distal	6	no	14.328	14.065	EPSD	COSMIC	6.822	Down-regulation
Atypical_PIKK_FRAP_MTOR_ST	Q9H063	MAF1	P42345	MTOR	S60	P61L	61	Missense	proximal	1	no	9.541	3.572	PhosphoSitePlus;EPSD	COSMIC	6.822	Loss
Atypical_PIKK_FRAP_MTOR_ST	Q9H063	MAF1	P42345	MTOR	S60	S65L	65	Missense	distal	5	no	9.541	11.028	PhosphoSitePlus;EPSD	COSMIC;GDSC;CCLE	6.822	Up-regulation
Atypical_PIKK_FRAP_MTOR_ST	Q9H063	MAF1	P42345	MTOR	S60	P53L	53	Missense	distal	-7	no	9.541	9.409	PhosphoSitePlus;EPSD	COSMIC	6.822	Down-regulation
Atypical_PIKK_FRAP_MTOR_ST	Q9H063	MAF1	P42345	MTOR	S68	P61L	61	Missense	distal	-7	no	10.497	10.364	EPSD;PhosphoSitePlus	COSMIC	6.822	Down-regulation
Atypical_PIKK_FRAP_MTOR_ST	Q9H063	MAF1	P42345	MTOR	S68	S65L	65	Missense	distal	-3	no	10.497	10.912	EPSD;PhosphoSitePlus	COSMIC;GDSC;CCLE	6.822	Up-regulation
Atypical_PIKK_FRAP_MTOR_ST	Q9H063	MAF1	P42345	MTOR	S205	V199I	199	Missense	distal	-6	no	11.368	11.430	EPSD	COSMIC	6.822	Up-regulation
Atypical_PIKK_FRAP_MTOR_ST	Q9H063	MAF1	P42345	MTOR	S205	G208D	208	Missense	distal	3	no	11.368	9.626	EPSD	COSMIC	6.822	Down-regulation
Atypical_PIKK_FRAP_MTOR_ST	Q9H063	MAF1	P42345	MTOR	S205	I198M	198	Missense	distal	-7	no	11.368	11.786	EPSD	COSMIC	6.822	Up-regulation
Atypical_PIKK_FRAP_MTOR_ST	Q9H063	MAF1	P42345	MTOR	S209	S214L	214	Missense	distal	5	no	8.135	9.622	EPSD	COSMIC	6.822	Up-regulation
Atypical_PIKK_FRAP_MTOR_ST	Q9H063	MAF1	P42345	MTOR	S209	G208D	208	Missense	proximal	-1	no	8.135	8.080	EPSD	COSMIC	6.822	Down-regulation
Atypical_PIKK_FRAP_MTOR_ST	Q9H063	MAF1	P42345	MTOR	S209	E215D	215	Missense	distal	6	no	8.135	7.683	EPSD	COSMIC	6.822	Down-regulation
Atypical_PIKK_FRAP_MTOR_ST	Q9H063	MAF1	P42345	MTOR	T245	E241D	241	Missense	distal	-4	no	13.162	14.313	EPSD	COSMIC	6.822	Up-regulation
Atypical_PIKK_FRAP_MTOR_ST	Q9H063	MAF1	P42345	MTOR	T245	D249N	249	Missense	distal	4	no	13.162	12.759	EPSD	COSMIC	6.822	Down-regulation
Atypical_PIKK_FRAP_MTOR_ST	Q9Y2J4	AMOTL2	P42345	MTOR	S50	G49W	49	Missense	proximal	-1	no	12.738	12.656	EPSD	COSMIC	6.822	Down-regulation
Atypical_PIKK_FRAP_MTOR_ST	Q9Y2J4	AMOTL2	P42345	MTOR	S50	A43V	43	Missense	distal	-7	no	12.738	12.850	EPSD	COSMIC	6.822	Up-regulation
Atypical_PIKK_FRAP_MTOR_ST	Q9Y2J4	AMOTL2	P42345	MTOR	S236	H238R	238	Missense	proximal	2	no	6.733	7.111	EPSD	COSMIC	6.822	Gain
Atypical_PIKK_FRAP_MTOR_ST	Q9Y2J4	AMOTL2	P42345	MTOR	S236	P229T	229	Missense	distal	-7	no	6.733	7.221	EPSD	COSMIC	6.822	Gain
Atypical_PIKK_FRAP_MTOR_ST	Q9Y2J4	AMOTL2	P42345	MTOR	S540	S540F	540	Missense	central	0	yes	11.791	0.000	EPSD	COSMIC;GDSC;CCLE	6.822	Loss
Atypical_PIKK_FRAP_MTOR_ST	Q9Y2J4	AMOTL2	P42345	MTOR	S602	S602F	602	Missense	central	0	yes	10.857	0.000	EPSD	COSMIC	6.822	Loss
Atypical_PIKK_FRAP_MTOR_ST	Q9Y2J4	AMOTL2	P42345	MTOR	S602	S606L	606	Missense	distal	4	no	10.857	10.217	EPSD	COSMIC	6.822	Down-regulation
Atypical_PIKK_FRAP_MTOR_ST	Q9Y2J4	AMOTL2	P42345	MTOR	S606	S602F	602	Missense	distal	-4	no	8.561	8.585	EPSD	COSMIC	6.822	Up-regulation
Atypical_PIKK_FRAP_MTOR_ST	Q9Y2J4	AMOTL2	P42345	MTOR	S606	S606L	606	Missense	central	0	yes	8.561	0.000	EPSD	COSMIC	6.822	Loss
Atypical_PIKK_FRAP_MTOR_ST	Q9Y2J4	AMOTL2	P42345	MTOR	S609	S602F	602	Missense	distal	-7	no	7.344	7.119	EPSD	COSMIC	6.822	Down-regulation
Atypical_PIKK_FRAP_MTOR_ST	Q9Y2J4	AMOTL2	P42345	MTOR	S609	S606L	606	Missense	distal	-3	no	7.344	7.759	EPSD	COSMIC	6.822	Up-regulation
Atypical_PIKK_FRAP_MTOR_ST	Q9Y2J4	AMOTL2	P42345	MTOR	S759	R756K	756	Missense	distal	-3	no	9.248	8.534	PhosphoSitePlus	COSMIC	6.822	Down-regulation
Atypical_PIKK_FRAP_MTOR_ST	Q9Y2J4	AMOTL2	P42345	MTOR	S759	A758S	758	Missense	proximal	-1	no	9.248	9.254	PhosphoSitePlus	COSMIC	6.822	Up-regulation
Atypical_PIKK_FRAP_MTOR_ST	Q9Y2J4	AMOTL2	P42345	MTOR	S759	R756I	756	Missense	distal	-3	no	9.248	9.337	PhosphoSitePlus	COSMIC	6.822	Up-regulation
Atypical_PIKK_FRAP_MTOR_ST	Q9Y2J4	AMOTL2	P42345	MTOR	S759	A758V	758	Missense	proximal	-1	no	9.248	9.176	PhosphoSitePlus	COSMIC	6.822	Down-regulation
Atypical_PIKK_FRAP_MTOR_ST	Q9Y2J4	AMOTL2	P42345	MTOR	S759	R756W	756	Missense	distal	-3	no	9.248	9.033	PhosphoSitePlus	COSMIC	6.822	Down-regulation
Atypical_PIKK_FRAP_MTOR_ST	Q9Y2J4	AMOTL2	P42345	MTOR	S762	R756K	756	Missense	distal	-6	no	11.749	11.411	EPSD	COSMIC	6.822	Down-regulation
Atypical_PIKK_FRAP_MTOR_ST	Q9Y2J4	AMOTL2	P42345	MTOR	S762	A758S	758	Missense	distal	-4	no	11.749	12.712	EPSD	COSMIC	6.822	Up-regulation
Atypical_PIKK_FRAP_MTOR_ST	Q9Y2J4	AMOTL2	P42345	MTOR	S762	R756I	756	Missense	distal	-6	no	11.749	11.082	EPSD	COSMIC	6.822	Down-regulation
Atypical_PIKK_FRAP_MTOR_ST	Q9Y2J4	AMOTL2	P42345	MTOR	S762	A758V	758	Missense	distal	-4	no	11.749	12.029	EPSD	COSMIC	6.822	Up-regulation
Atypical_PIKK_FRAP_MTOR_ST	Q9Y2J4	AMOTL2	P42345	MTOR	S762	R756W	756	Missense	distal	-6	no	11.749	12.122	EPSD	COSMIC	6.822	Up-regulation
Atypical_PIKK_FRAP_MTOR_ST	Q9Y2J4	AMOTL2	P42345	MTOR	S766	L771F	771	Missense	distal	5	no	9.032	8.132	EPSD	COSMIC	6.822	Down-regulation
Atypical_PIKK_FRAP_MTOR_ST	P04198	MYCN	P42345	MTOR	S62	P57H	57	Missense	distal	-5	no	11.056	11.154	PhosphoSitePlus	COSMIC;GDSC;CCLE	6.822	Up-regulation
Atypical_PIKK_FRAP_MTOR_ST	P04198	MYCN	P42345	MTOR	S62	A68G	68	Missense	distal	6	no	11.056	11.637	PhosphoSitePlus	COSMIC	6.822	Up-regulation
Atypical_PIKK_FRAP_MTOR_ST	P04198	MYCN	P42345	MTOR	S62	S64G	64	Missense	proximal	2	no	11.056	10.876	PhosphoSitePlus	COSMIC	6.822	Down-regulation
Atypical_PIKK_FRAP_MTOR_ST	P04198	MYCN	P42345	MTOR	S62	P60S	60	Missense	proximal	-2	no	11.056	10.700	PhosphoSitePlus	COSMIC	6.822	Down-regulation
Atypical_PIKK_FRAP_MTOR_ST	P04198	MYCN	P42345	MTOR	S62	P63L	63	Missense	proximal	1	no	11.056	5.087	PhosphoSitePlus	COSMIC	6.822	Loss
Atypical_PIKK_FRAP_MTOR_ST	P04198	MYCN	P42345	MTOR	S62	P57S	57	Missense	distal	-5	no	11.056	11.008	PhosphoSitePlus	COSMIC	6.822	Down-regulation
Atypical_PIKK_FRAP_MTOR_ST	P04198	MYCN	P42345	MTOR	S62	P60L	60	Missense	proximal	-2	no	11.056	10.565	PhosphoSitePlus	COSMIC	6.822	Down-regulation
Atypical_PIKK_FRAP_MTOR_ST	P04198	MYCN	P42345	MTOR	S62	P59L	59	Missense	distal	-3	no	11.056	11.903	PhosphoSitePlus	COSMIC	6.822	Up-regulation
Atypical_PIKK_FRAP_MTOR_ST	P04198	MYCN	P42345	MTOR	S62	L55M	55	Missense	distal	-7	no	11.056	11.038	PhosphoSitePlus	COSMIC	6.822	Down-regulation
Atypical_PIKK_FRAP_MTOR_ST	P04198	MYCN	P42345	MTOR	S149	A147T	147	Missense	proximal	-2	no	17.371	16.874	EPSD	COSMIC	6.822	Down-regulation
Atypical_PIKK_FRAP_MTOR_ST	P04198	MYCN	P42345	MTOR	S149	A152D	152	Missense	distal	3	no	17.371	15.642	EPSD	COSMIC	6.822	Down-regulation
Atypical_PIKK_FRAP_MTOR_ST	P04198	MYCN	P42345	MTOR	S149	A143T	143	Missense	distal	-6	no	17.371	17.650	EPSD	COSMIC	6.822	Up-regulation
Atypical_PIKK_FRAP_MTOR_ST	P04198	MYCN	P42345	MTOR	S156	A152D	152	Missense	distal	-4	no	7.979	9.971	EPSD	COSMIC	6.822	Up-regulation
Atypical_PIKK_FRAP_MTOR_ST	P04198	MYCN	P42345	MTOR	S253	D258N	258	Missense	distal	5	no	5.415	6.862	EPSD	COSMIC	6.822	Gain
Atypical_PIKK_FRAP_MTOR_ST	P04198	MYCN	P42345	MTOR	S288	S289P	289	Missense	proximal	1	no	2.820	11.344	EPSD	COSMIC	6.822	Gain
Atypical_PIKK_FRAP_MTOR_ST	P04198	MYCN	P42345	MTOR	S315	L318R	318	Missense	distal	3	no	5.583	7.572	EPSD	COSMIC	6.822	Gain
Atypical_PIKK_FRAP_MTOR_ST	P04198	MYCN	P42345	MTOR	S369	P364S	364	Missense	distal	-5	no	8.029	7.981	EPSD	COSMIC	6.822	Down-regulation
Atypical_PIKK_FRAP_MTOR_ST	P04198	MYCN	P42345	MTOR	S369	P365A	365	Missense	distal	-4	no	8.029	7.195	EPSD	COSMIC;GDSC	6.822	Down-regulation
Atypical_PIKK_FRAP_MTOR_ST	P04198	MYCN	P42345	MTOR	S369	K366T	366	Missense	distal	-3	no	8.029	7.958	EPSD	COSMIC	6.822	Down-regulation
Atypical_PIKK_FRAP_MTOR_ST	P04198	MYCN	P42345	MTOR	S369	P365Q	365	Missense	distal	-4	no	8.029	7.776	EPSD	COSMIC	6.822	Down-regulation
Atypical_PIKK_FRAP_MTOR_ST	P04198	MYCN	P42345	MTOR	S369	L370S	370	Missense	proximal	1	no	8.029	5.474	EPSD	COSMIC	6.822	Loss
Atypical_PIKK_FRAP_MTOR_ST	P04198	MYCN	P42345	MTOR	S369	P365S	365	Missense	distal	-4	no	8.029	8.158	EPSD	COSMIC	6.822	Up-regulation
Atypical_PIKK_FRAP_MTOR_ST	P04198	MYCN	P42345	MTOR	S369	R373L	373	Missense	distal	4	no	8.029	7.962	EPSD	COSMIC	6.822	Down-regulation
Atypical_PIKK_FRAP_MTOR_ST	P04198	MYCN	P42345	MTOR	S371	P364S	364	Missense	distal	-7	no	9.494	9.931	EPSD	COSMIC	6.822	Up-regulation
Atypical_PIKK_FRAP_MTOR_ST	P04198	MYCN	P42345	MTOR	S371	P365A	365	Missense	distal	-6	no	9.494	9.136	EPSD	COSMIC;GDSC	6.822	Down-regulation
Atypical_PIKK_FRAP_MTOR_ST	P04198	MYCN	P42345	MTOR	S371	E378K	378	Missense	distal	7	no	9.494	9.590	EPSD	COSMIC	6.822	Up-regulation
Atypical_PIKK_FRAP_MTOR_ST	P04198	MYCN	P42345	MTOR	S371	K366T	366	Missense	distal	-5	no	9.494	9.514	EPSD	COSMIC	6.822	Up-regulation
Atypical_PIKK_FRAP_MTOR_ST	P04198	MYCN	P42345	MTOR	S371	E378G	378	Missense	distal	7	no	9.494	10.328	EPSD	COSMIC	6.822	Up-regulation
Atypical_PIKK_FRAP_MTOR_ST	P04198	MYCN	P42345	MTOR	S371	P365Q	365	Missense	distal	-6	no	9.494	9.316	EPSD	COSMIC	6.822	Down-regulation
Atypical_PIKK_FRAP_MTOR_ST	P04198	MYCN	P42345	MTOR	S371	L370S	370	Missense	proximal	-1	no	9.494	9.695	EPSD	COSMIC	6.822	Up-regulation
Atypical_PIKK_FRAP_MTOR_ST	P04198	MYCN	P42345	MTOR	S371	P365S	365	Missense	distal	-6	no	9.494	9.473	EPSD	COSMIC	6.822	Down-regulation
Atypical_PIKK_FRAP_MTOR_ST	P04198	MYCN	P42345	MTOR	S371	R373L	373	Missense	proximal	2	no	9.494	11.011	EPSD	COSMIC	6.822	Up-regulation
Atypical_PIKK_FRAP_MTOR_ST	P04198	MYCN	P42345	MTOR	S377	E378K	378	Missense	proximal	1	no	7.775	5.027	EPSD	COSMIC	6.822	Loss
Atypical_PIKK_FRAP_MTOR_ST	P04198	MYCN	P42345	MTOR	S377	E378G	378	Missense	proximal	1	no	7.775	4.331	EPSD	COSMIC	6.822	Loss
Atypical_PIKK_FRAP_MTOR_ST	P04198	MYCN	P42345	MTOR	S377	L370S	370	Missense	distal	-7	no	7.775	8.344	EPSD	COSMIC	6.822	Up-regulation
Atypical_PIKK_FRAP_MTOR_ST	P04198	MYCN	P42345	MTOR	S377	R383H	383	Missense	distal	6	no	7.775	8.091	EPSD	COSMIC	6.822	Up-regulation
Atypical_PIKK_FRAP_MTOR_ST	P04198	MYCN	P42345	MTOR	S377	R373L	373	Missense	distal	-4	no	7.775	7.345	EPSD	COSMIC	6.822	Down-regulation
Atypical_PIKK_FRAP_MTOR_ST	Q9H4A3	WNK1	P42345	MTOR	S11	P13L	13	Missense	proximal	2	no	8.560	7.870	EPSD	COSMIC	6.822	Down-regulation
Atypical_PIKK_FRAP_MTOR_ST	Q9H4A3	WNK1	P42345	MTOR	S19	P13L	13	Missense	distal	-6	no	14.268	13.493	EPSD	COSMIC	6.822	Down-regulation
Atypical_PIKK_FRAP_MTOR_ST	Q9H4A3	WNK1	P42345	MTOR	S167	S167F	167	Missense	central	0	yes	7.875	0.000	EPSD	COSMIC	6.822	Loss
Atypical_PIKK_FRAP_MTOR_ST	Q9H4A3	WNK1	P42345	MTOR	S167	V166L	166	Missense	proximal	-1	no	7.875	7.751	EPSD	COSMIC	6.822	Down-regulation
Atypical_PIKK_FRAP_MTOR_ST	Q9H4A3	WNK1	P42345	MTOR	S1197	Q1204R	1204	Missense	distal	7	no	6.434	6.834	EPSD	COSMIC	6.822	Gain
Atypical_PIKK_FRAP_MTOR_ST	Q9H4A3	WNK1	P42345	MTOR	S1261	P1262L	1262	Missense	proximal	1	no	12.184	6.215	EPSD	COSMIC	6.822	Loss
Atypical_PIKK_FRAP_MTOR_ST	Q9H4A3	WNK1	P42345	MTOR	S1261	R1267Q	1267	Missense	distal	6	no	12.184	12.568	EPSD	COSMIC	6.822	Up-regulation
Atypical_PIKK_FRAP_MTOR_ST	Q9H4A3	WNK1	P42345	MTOR	S1289	A1287S	1287	Missense	proximal	-2	no	15.941	15.379	EPSD	COSMIC	6.822	Down-regulation
Atypical_PIKK_FRAP_MTOR_ST	Q9H4A3	WNK1	P42345	MTOR	S1289	A1284E	1284	Missense	distal	-5	no	15.941	15.607	EPSD	COSMIC	6.822	Down-regulation
Atypical_PIKK_FRAP_MTOR_ST	Q9H4A3	WNK1	P42345	MTOR	S1289	A1283D	1283	Missense	distal	-6	no	15.941	16.383	EPSD	COSMIC	6.822	Up-regulation
Atypical_PIKK_FRAP_MTOR_ST	Q9H4A3	WNK1	P42345	MTOR	S1289	H1296Y	1296	Missense	distal	7	no	15.941	14.906	EPSD	COSMIC;CCLE	6.822	Down-regulation
Atypical_PIKK_FRAP_MTOR_ST	Q9H4A3	WNK1	P42345	MTOR	S1289	A1284T	1284	Missense	distal	-5	no	15.941	15.920	EPSD	COSMIC	6.822	Down-regulation
Atypical_PIKK_FRAP_MTOR_ST	Q9H4A3	WNK1	P42345	MTOR	S1299	S1302A	1302	Missense	distal	3	no	5.808	6.863	EPSD	COSMIC	6.822	Gain
Atypical_PIKK_FRAP_MTOR_ST	Q9H4A3	WNK1	P42345	MTOR	S1299	Q1304L	1304	Missense	distal	5	no	5.808	7.110	EPSD	COSMIC	6.822	Gain
Atypical_PIKK_FRAP_MTOR_ST	Q9H4A3	WNK1	P42345	MTOR	S1805	Q1799E	1799	Missense	distal	-6	no	10.006	10.078	EPSD	COSMIC;GDSC;CCLE	6.822	Up-regulation
Atypical_PIKK_FRAP_MTOR_ST	Q9H4A3	WNK1	P42345	MTOR	S1805	M1808I	1808	Missense	distal	3	no	10.006	10.173	EPSD	COSMIC	6.822	Up-regulation
Atypical_PIKK_FRAP_MTOR_ST	Q9H4A3	WNK1	P42345	MTOR	S1805	L1804F	1804	Missense	proximal	-1	no	10.006	10.024	EPSD	COSMIC	6.822	Up-regulation
Atypical_PIKK_FRAP_MTOR_ST	Q9H4A3	WNK1	P42345	MTOR	S1897	S1898I	1898	Missense	proximal	1	no	5.864	9.329	EPSD	COSMIC	6.822	Gain
Atypical_PIKK_FRAP_MTOR_ST	Q9H4A3	WNK1	P42345	MTOR	S1899	S1897N	1897	Missense	proximal	-2	no	10.216	9.625	EPSD	COSMIC	6.822	Down-regulation
Atypical_PIKK_FRAP_MTOR_ST	Q9H4A3	WNK1	P42345	MTOR	S1899	K1906I	1906	Missense	distal	7	no	10.216	10.945	EPSD	COSMIC	6.822	Up-regulation
Atypical_PIKK_FRAP_MTOR_ST	Q9H4A3	WNK1	P42345	MTOR	S1899	S1892F	1892	Missense	distal	-7	no	10.216	9.991	EPSD	COSMIC	6.822	Down-regulation
Atypical_PIKK_FRAP_MTOR_ST	Q9H4A3	WNK1	P42345	MTOR	S1899	S1898I	1898	Missense	proximal	-1	no	10.216	9.980	EPSD	COSMIC	6.822	Down-regulation
Atypical_PIKK_FRAP_MTOR_ST	Q9H4A3	WNK1	P42345	MTOR	S1978	P1980S	1980	Missense	proximal	2	no	8.996	8.502	EPSD	COSMIC	6.822	Down-regulation
Atypical_PIKK_FRAP_MTOR_ST	Q9H4A3	WNK1	P42345	MTOR	S2029	D2024E	2024	Missense	distal	-5	no	8.544	8.283	EPSD	COSMIC	6.822	Down-regulation
Atypical_PIKK_FRAP_MTOR_ST	Q9H4A3	WNK1	P42345	MTOR	S2029	V2023L	2023	Missense	distal	-6	no	8.544	8.411	EPSD	COSMIC	6.822	Down-regulation
Atypical_PIKK_FRAP_MTOR_ST	Q9H4A3	WNK1	P42345	MTOR	S2029	S2027N	2027	Missense	proximal	-2	no	8.544	7.953	EPSD	COSMIC	6.822	Down-regulation
Atypical_PIKK_FRAP_MTOR_ST	Q9H4A3	WNK1	P42345	MTOR	S2032	S2027N	2027	Missense	distal	-5	no	8.691	8.602	PhosphoSitePlus	COSMIC	6.822	Down-regulation
Atypical_PIKK_FRAP_MTOR_ST	Q9H4A3	WNK1	P42345	MTOR	S2188	S2188N	2188	Missense	central	0	yes	12.014	0.000	EPSD	COSMIC	6.822	Loss
Atypical_PIKK_FRAP_MTOR_ST	Q9H4A3	WNK1	P42345	MTOR	S2188	S2190C	2190	Missense	proximal	2	no	12.014	10.468	EPSD	COSMIC	6.822	Down-regulation
Atypical_PIKK_FRAP_MTOR_ST	Q9H4A3	WNK1	P42345	MTOR	S2188	P2189L	2189	Missense	proximal	1	no	12.014	6.045	EPSD	COSMIC	6.822	Loss
Atypical_PIKK_FRAP_MTOR_ST	Q9H4A3	WNK1	P42345	MTOR	S2188	S2191G	2191	Missense	distal	3	no	12.014	13.082	EPSD	COSMIC;GDSC;CCLE	6.822	Up-regulation
Atypical_PIKK_FRAP_MTOR_ST	Q9H4A3	WNK1	P42345	MTOR	S2294	G2300S	2300	Missense	distal	6	no	8.618	8.688	EPSD	COSMIC	6.822	Up-regulation
Atypical_PIKK_FRAP_MTOR_ST	Q9H4A3	WNK1	P42345	MTOR	S2294	G2289W	2289	Missense	distal	-5	no	8.618	8.750	EPSD	COSMIC	6.822	Up-regulation
Atypical_PIKK_FRAP_MTOR_ST	Q9H4A3	WNK1	P42345	MTOR	S2294	A2287E	2287	Missense	distal	-7	no	8.618	9.053	EPSD	COSMIC	6.822	Up-regulation
Atypical_PIKK_FRAP_MTOR_ST	Q9H4A3	WNK1	P42345	MTOR	S2294	T2296A	2296	Missense	proximal	2	no	8.618	7.913	EPSD	COSMIC	6.822	Down-regulation
Atypical_PIKK_FRAP_MTOR_ST	Q9H4A3	WNK1	P42345	MTOR	S2370	G2376D	2376	Missense	distal	6	no	12.717	12.504	EPSD	COSMIC	6.822	Down-regulation
Atypical_PIKK_FRAP_MTOR_ST	Q9H4A3	WNK1	P42345	MTOR	S2370	S2377T	2377	Missense	distal	7	no	12.717	11.772	EPSD	COSMIC	6.822	Down-regulation
Atypical_PIKK_FRAP_MTOR_ST	Q9H4A3	WNK1	P42345	MTOR	S2372	G2376D	2376	Missense	distal	4	no	6.675	7.127	EPSD	COSMIC	6.822	Gain
Atypical_PIKK_FRAP_MTOR_ST	Q9H4A3	WNK1	P42345	MTOR	T2381	G2376D	2376	Missense	distal	-5	no	7.217	7.105	EPSD	COSMIC	6.822	Down-regulation
Atypical_PIKK_FRAP_MTOR_ST	Q9H4A3	WNK1	P42345	MTOR	T2381	R2380Q	2380	Missense	proximal	-1	no	7.217	7.236	EPSD	COSMIC	6.822	Up-regulation
Atypical_PIKK_FRAP_MTOR_ST	Q9H4A3	WNK1	P42345	MTOR	T2381	S2377T	2377	Missense	distal	-4	no	7.217	6.715	EPSD	COSMIC	6.822	Loss
Other_NEK_NEK6_NEK6_ST	O95235	KIF20A	Q9HC98	NEK6	S47	S44F	44	Missense	distal	-3	no	6.525	95.573	EPSD	COSMIC	73.015	Gain
Other_NEK_NEK6_NEK6_ST	O95235	KIF20A	Q9HC98	NEK6	S240	R243K	243	Missense	distal	3	no	115.933	115.863	EPSD;PhosphoSitePlus	COSMIC	73.015	Down-regulation
Other_NEK_NEK6_NEK6_ST	O95235	KIF20A	Q9HC98	NEK6	S244	R243K	243	Missense	proximal	-1	no	113.449	115.552	EPSD;PhosphoSitePlus	COSMIC	73.015	Up-regulation
Other_NEK_NEK6_NEK6_ST	O95235	KIF20A	Q9HC98	NEK6	T279	D277H	277	Missense	proximal	-2	no	86.783	81.604	EPSD	COSMIC	73.015	Down-regulation
Other_NEK_NEK6_NEK6_ST	O95235	KIF20A	Q9HC98	NEK6	T279	H281N	281	Missense	proximal	2	no	86.783	85.690	EPSD	COSMIC	73.015	Down-regulation
Other_NEK_NEK6_NEK6_ST	O95235	KIF20A	Q9HC98	NEK6	T279	R282P	282	Missense	distal	3	no	86.783	86.842	EPSD	COSMIC	73.015	Up-regulation
Other_NEK_NEK6_NEK6_ST	O95235	KIF20A	Q9HC98	NEK6	T279	A284P	284	Missense	distal	5	no	86.783	84.640	EPSD	COSMIC	73.015	Down-regulation
Other_NEK_NEK6_NEK6_ST	O95235	KIF20A	Q9HC98	NEK6	S412	L406P	406	Missense	distal	-6	no	77.090	77.217	EPSD	COSMIC	73.015	Up-regulation
Other_NEK_NEK6_NEK6_ST	O95235	KIF20A	Q9HC98	NEK6	S412	R414C	414	Missense	proximal	2	no	77.090	77.362	EPSD	COSMIC;GDSC;CCLE	73.015	Up-regulation
Other_NEK_NEK6_NEK6_ST	O95235	KIF20A	Q9HC98	NEK6	S489	A488S	488	Missense	proximal	-1	no	73.271	73.511	EPSD	COSMIC	73.015	Up-regulation
Other_NEK_NEK6_NEK6_ST	O95235	KIF20A	Q9HC98	NEK6	S489	T490A	490	Missense	proximal	1	no	73.271	72.527	EPSD	COSMIC	73.015	Loss
Other_NEK_NEK6_NEK6_ST	O95235	KIF20A	Q9HC98	NEK6	S677	L674P	674	Missense	distal	-3	no	76.103	69.670	EPSD	COSMIC	73.015	Loss
Other_NEK_NEK6_NEK6_ST	O95235	KIF20A	Q9HC98	NEK6	S677	A684V	684	Missense	distal	7	no	76.103	75.024	EPSD	COSMIC	73.015	Down-regulation
Other_NEK_NEK6_NEK6_ST	O95235	KIF20A	Q9HC98	NEK6	S677	R676Q	676	Missense	proximal	-1	no	76.103	74.338	EPSD	COSMIC	73.015	Down-regulation
Other_NEK_NEK6_NEK6_ST	O95235	KIF20A	Q9HC98	NEK6	S683	A684V	684	Missense	proximal	1	no	107.958	108.369	EPSD;PhosphoSitePlus	COSMIC	73.015	Up-regulation
Other_NEK_NEK6_NEK6_ST	O95235	KIF20A	Q9HC98	NEK6	S683	R676Q	676	Missense	distal	-7	no	107.958	108.076	EPSD;PhosphoSitePlus	COSMIC	73.015	Up-regulation
Other_NEK_NEK6_NEK6_ST	O95235	KIF20A	Q9HC98	NEK6	S754	E759D	759	Missense	distal	5	no	116.554	120.377	PhosphoSitePlus;EPSD	COSMIC	73.015	Up-regulation
Other_NEK_NEK6_NEK6_ST	O95235	KIF20A	Q9HC98	NEK6	S754	E747D	747	Missense	distal	-7	no	116.554	116.920	PhosphoSitePlus;EPSD	COSMIC	73.015	Up-regulation
Other_NEK_NEK6_NEK6_ST	O95235	KIF20A	Q9HC98	NEK6	T857	R856C	856	Missense	proximal	-1	no	76.426	72.918	EPSD	COSMIC	73.015	Loss
Other_NEK_NEK6_NEK6_ST	O95235	KIF20A	Q9HC98	NEK6	T857	P855T	855	Missense	proximal	-2	no	76.426	77.260	EPSD	COSMIC;GDSC;CCLE	73.015	Up-regulation
Other_NEK_NEK6_NEK6_ST	O95235	KIF20A	Q9HC98	NEK6	T857	R851Q	851	Missense	distal	-6	no	76.426	76.413	EPSD	COSMIC	73.015	Down-regulation
Other_NEK_NEK6_NEK6_ST	O95235	KIF20A	Q9HC98	NEK6	T857	L853F	853	Missense	distal	-4	no	76.426	75.768	EPSD	COSMIC	73.015	Down-regulation
Other_NEK_NEK6_NEK6_ST	O95235	KIF20A	Q9HC98	NEK6	T857	P855S	855	Missense	proximal	-2	no	76.426	84.919	EPSD	COSMIC	73.015	Up-regulation
Other_NEK_NEK6_NEK6_ST	O95235	KIF20A	Q9HC98	NEK6	T857	T859I	859	Missense	proximal	2	no	76.426	79.690	EPSD	COSMIC	73.015	Up-regulation
Other_NEK_NEK6_NEK6_ST	O95235	KIF20A	Q9HC98	NEK6	T857	R856Q	856	Missense	proximal	-1	no	76.426	74.661	EPSD	COSMIC	73.015	Down-regulation
Other_NEK_NEK6_NEK6_ST	P23443	RPS6KB1	Q9HC98	NEK6	S53	G60A	60	Missense	distal	7	no	115.946	116.613	EPSD;PhosphoSitePlus	COSMIC	73.015	Up-regulation
Other_NEK_NEK6_NEK6_ST	P23443	RPS6KB1	Q9HC98	NEK6	S394	P391S	391	Missense	distal	-3	no	108.869	13.118	EPSD	COSMIC	73.015	Loss
Other_NEK_NEK6_NEK6_ST	P23443	RPS6KB1	Q9HC98	NEK6	S394	S401N	401	Missense	distal	7	no	108.869	108.931	EPSD	COSMIC;CCLE	73.015	Up-regulation
Other_NEK_NEK6_NEK6_ST	P23443	RPS6KB1	Q9HC98	NEK6	S394	S398T	398	Missense	distal	4	no	108.869	108.499	EPSD	COSMIC	73.015	Down-regulation
Other_NEK_NEK6_NEK6_ST	P23443	RPS6KB1	Q9HC98	NEK6	S394	R388G	388	Missense	distal	-6	no	108.869	108.674	EPSD	COSMIC	73.015	Down-regulation
Other_NEK_NEK6_NEK6_ST	P23443	RPS6KB1	Q9HC98	NEK6	S398	P391S	391	Missense	distal	-7	no	111.022	111.225	EPSD	COSMIC	73.015	Up-regulation
Other_NEK_NEK6_NEK6_ST	P23443	RPS6KB1	Q9HC98	NEK6	S398	S401N	401	Missense	distal	3	no	111.022	110.958	EPSD	COSMIC;CCLE	73.015	Down-regulation
Other_NEK_NEK6_NEK6_ST	P23443	RPS6KB1	Q9HC98	NEK6	S398	A404V	404	Missense	distal	6	no	111.022	110.906	EPSD	COSMIC	73.015	Down-regulation
Other_NEK_NEK6_NEK6_ST	P23443	RPS6KB1	Q9HC98	NEK6	S403	S401N	401	Missense	proximal	-2	no	108.845	106.380	PhosphoSitePlus;EPSD	COSMIC;CCLE	73.015	Down-regulation
Other_NEK_NEK6_NEK6_ST	P23443	RPS6KB1	Q9HC98	NEK6	S403	S398T	398	Missense	distal	-5	no	108.845	109.012	PhosphoSitePlus;EPSD	COSMIC	73.015	Up-regulation
Other_NEK_NEK6_NEK6_ST	P23443	RPS6KB1	Q9HC98	NEK6	S403	A404V	404	Missense	proximal	1	no	108.845	109.255	PhosphoSitePlus;EPSD	COSMIC	73.015	Up-regulation
Other_NEK_NEK6_NEK6_ST	P23443	RPS6KB1	Q9HC98	NEK6	T412	T412A	412	Missense	central	0	yes	110.257	0.000	EPSD;PhosphoSitePlus	COSMIC	73.015	Loss
Other_NEK_NEK6_NEK6_ST	P23443	RPS6KB1	Q9HC98	NEK6	T412	V414E	414	Missense	proximal	2	no	110.257	109.073	EPSD;PhosphoSitePlus	COSMIC	73.015	Down-regulation
Other_NEK_NEK6_NEK6_ST	P23443	RPS6KB1	Q9HC98	NEK6	S441	G440A	440	Missense	proximal	-1	no	74.133	77.494	EPSD	COSMIC	73.015	Up-regulation
Other_NEK_NEK6_NEK6_ST	P23443	RPS6KB1	Q9HC98	NEK6	S441	P445L	445	Missense	distal	4	no	74.133	73.699	EPSD	COSMIC	73.015	Down-regulation
Other_NEK_NEK6_NEK6_ST	P23443	RPS6KB1	Q9HC98	NEK6	S441	R436Q	436	Missense	distal	-5	no	74.133	74.042	EPSD	COSMIC	73.015	Down-regulation
Other_NEK_NEK6_NEK6_ST	O00141	SGK1	Q9HC98	NEK6	S61	P63S	63	Missense	proximal	2	no	84.877	83.384	EPSD	COSMIC;CCLE	73.015	Down-regulation
Other_NEK_NEK6_NEK6_ST	O00141	SGK1	Q9HC98	NEK6	S61	Q55H	55	Missense	distal	-6	no	84.877	84.686	EPSD	COSMIC	73.015	Down-regulation
Other_NEK_NEK6_NEK6_ST	O00141	SGK1	Q9HC98	NEK6	S61	Q55E	55	Missense	distal	-6	no	84.877	84.781	EPSD	COSMIC	73.015	Down-regulation
Other_NEK_NEK6_NEK6_ST	O00141	SGK1	Q9HC98	NEK6	S61	K59N	59	Missense	proximal	-2	no	84.877	82.712	EPSD	COSMIC	73.015	Down-regulation
Other_NEK_NEK6_NEK6_ST	O00141	SGK1	Q9HC98	NEK6	S61	S61F	61	Missense	central	0	yes	84.877	0.000	EPSD	COSMIC	73.015	Loss
Other_NEK_NEK6_NEK6_ST	O00141	SGK1	Q9HC98	NEK6	S88	Q81R	81	Missense	distal	-7	no	86.103	85.985	EPSD	COSMIC	73.015	Down-regulation
Other_NEK_NEK6_NEK6_ST	O00141	SGK1	Q9HC98	NEK6	S88	S89F	89	Missense	proximal	1	no	86.103	88.561	EPSD	COSMIC	73.015	Up-regulation
Other_NEK_NEK6_NEK6_ST	O00141	SGK1	Q9HC98	NEK6	S88	H92R	92	Missense	distal	4	no	86.103	85.185	EPSD	COSMIC	73.015	Down-regulation
Other_NEK_NEK6_NEK6_ST	O00141	SGK1	Q9HC98	NEK6	S88	P91L	91	Missense	distal	3	no	86.103	86.084	EPSD	COSMIC	73.015	Down-regulation
Other_NEK_NEK6_NEK6_ST	O00141	SGK1	Q9HC98	NEK6	S88	S88A	88	Missense	central	0	yes	86.103	0.000	EPSD	COSMIC	73.015	Loss
Other_NEK_NEK6_NEK6_ST	O00141	SGK1	Q9HC98	NEK6	S88	A93G	93	Missense	distal	5	no	86.103	84.375	EPSD	COSMIC	73.015	Down-regulation
Other_NEK_NEK6_NEK6_ST	O00141	SGK1	Q9HC98	NEK6	S88	P87S	87	Missense	proximal	-1	no	86.103	89.034	EPSD	COSMIC	73.015	Up-regulation
Other_NEK_NEK6_NEK6_ST	O00141	SGK1	Q9HC98	NEK6	S88	P91S	91	Missense	distal	3	no	86.103	86.146	EPSD	COSMIC	73.015	Up-regulation
Other_NEK_NEK6_NEK6_ST	O00141	SGK1	Q9HC98	NEK6	S377	L382F	382	Missense	distal	5	no	102.912	103.062	PhosphoSitePlus;EPSD	COSMIC	73.015	Up-regulation
Other_NEK_NEK6_NEK6_ST	O00141	SGK1	Q9HC98	NEK6	S377	P371L	371	Missense	distal	-6	no	102.912	102.785	PhosphoSitePlus;EPSD	COSMIC	73.015	Down-regulation
Other_NEK_NEK6_NEK6_ST	O00141	SGK1	Q9HC98	NEK6	S422	E416G	416	Missense	distal	-6	no	110.430	110.345	EPSD;PhosphoSitePlus	COSMIC	73.015	Down-regulation
Other_NEK_NEK6_NEK6_ST	O00141	SGK1	Q9HC98	NEK6	S422	A424S	424	Missense	proximal	2	no	110.430	110.857	EPSD;PhosphoSitePlus	COSMIC	73.015	Up-regulation
Other_NEK_NEK6_NEK6_ST	O00141	SGK1	Q9HC98	NEK6	S422	T427M	427	Missense	distal	5	no	110.430	109.789	EPSD;PhosphoSitePlus	COSMIC	73.015	Down-regulation
Other_NEK_NEK6_NEK6_ST	Q08345	DDR1	Q9HC98	NEK6	T469	G467V	467	Missense	proximal	-2	no	82.075	77.499	EPSD	COSMIC	73.015	Down-regulation
Other_NEK_NEK6_NEK6_ST	Q08345	DDR1	Q9HC98	NEK6	S509	N502S	502	Missense	distal	-7	no	79.836	79.932	EPSD	COSMIC	73.015	Up-regulation
Other_NEK_NEK6_NEK6_ST	Q08345	DDR1	Q9HC98	NEK6	S509	A505V	505	Missense	distal	-4	no	79.836	79.619	EPSD	COSMIC	73.015	Down-regulation
Other_NEK_NEK6_NEK6_ST	Q08345	DDR1	Q9HC98	NEK6	S509	P511L	511	Missense	proximal	2	no	79.836	77.046	EPSD	COSMIC	73.015	Down-regulation
Other_NEK_NEK6_NEK6_ST	Q08345	DDR1	Q9HC98	NEK6	S788	M787I	787	Missense	proximal	-1	no	101.878	96.443	PhosphoSitePlus	COSMIC	73.015	Down-regulation
Other_NEK_NEK6_NEK6_ST	Q08345	DDR1	Q9HC98	NEK6	S788	A783T	783	Missense	distal	-5	no	101.878	101.953	PhosphoSitePlus	COSMIC	73.015	Up-regulation
Other_NEK_NEK6_NEK6_ST	Q08345	DDR1	Q9HC98	NEK6	S788	G794V	794	Missense	distal	6	no	101.878	102.788	PhosphoSitePlus	COSMIC	73.015	Up-regulation
Other_NEK_NEK6_NEK6_ST	Q08345	DDR1	Q9HC98	NEK6	S788	R789C	789	Missense	proximal	1	no	101.878	102.658	PhosphoSitePlus	COSMIC	73.015	Up-regulation
Other_NEK_NEK6_NEK6_ST	Q96AP0	ACD	Q9HC98	NEK6	S420	A419T	419	Missense	proximal	-1	no	72.476	73.759	EPSD	COSMIC;GDSC	73.015	Gain
Other_NEK_NEK6_NEK6_ST	Q96AP0	ACD	Q9HC98	NEK6	S435	R437H	437	Missense	proximal	2	no	80.738	81.662	EPSD	COSMIC	73.015	Up-regulation
Other_NEK_NEK6_NEK6_ST	Q96AP0	ACD	Q9HC98	NEK6	S510	V515G	515	Missense	distal	5	no	76.360	74.753	EPSD	COSMIC	73.015	Down-regulation
Other_NEK_NEK6_NEK6_ST	Q96AP0	ACD	Q9HC98	NEK6	S510	Y504C	504	Missense	distal	-6	no	76.360	76.463	EPSD	COSMIC	73.015	Up-regulation
Other_NEK_NEK6_NEK6_ST	Q08999	RBL2	Q9HC98	NEK6	S40	Q44R	44	Missense	distal	4	no	75.408	71.333	EPSD	COSMIC	73.015	Loss
Other_NEK_NEK6_NEK6_ST	Q08999	RBL2	Q9HC98	NEK6	T421	P414L	414	Missense	distal	-7	no	84.338	84.403	EPSD	COSMIC	73.015	Up-regulation
Other_NEK_NEK6_NEK6_ST	Q08999	RBL2	Q9HC98	NEK6	T421	P414H	414	Missense	distal	-7	no	84.338	84.291	EPSD	COSMIC	73.015	Down-regulation
Other_NEK_NEK6_NEK6_ST	Q08999	RBL2	Q9HC98	NEK6	T421	R428S	428	Missense	distal	7	no	84.338	83.840	EPSD	COSMIC	73.015	Down-regulation
Other_NEK_NEK6_NEK6_ST	Q08999	RBL2	Q9HC98	NEK6	T421	S425G	425	Missense	distal	4	no	84.338	82.723	EPSD	COSMIC	73.015	Down-regulation
Other_NEK_NEK6_NEK6_ST	Q08999	RBL2	Q9HC98	NEK6	T421	R428H	428	Missense	distal	7	no	84.338	84.311	EPSD	COSMIC	73.015	Down-regulation
Other_NEK_NEK6_NEK6_ST	Q08999	RBL2	Q9HC98	NEK6	S1035	S1035Y	1035	Missense	central	0	yes	73.595	0.000	EPSD	COSMIC	73.015	Loss
Other_NEK_NEK6_NEK6_ST	Q08999	RBL2	Q9HC98	NEK6	S1035	P1036L	1036	Missense	proximal	1	no	73.595	69.696	EPSD	COSMIC;CCLE	73.015	Loss
Other_NEK_NEK6_NEK6_ST	Q08999	RBL2	Q9HC98	NEK6	S1080	K1083N	1083	Missense	distal	3	no	78.289	78.396	EPSD	COSMIC	73.015	Up-regulation
Other_NEK_NEK6_NEK6_ST	P52948	NUP98	Q9HC98	NEK6	S231	G229E	229	Missense	proximal	-2	no	73.361	65.009	EPSD	COSMIC	73.015	Loss
Other_NEK_NEK6_NEK6_ST	P52948	NUP98	Q9HC98	NEK6	S511	S507I	507	Missense	distal	-4	no	78.783	77.969	EPSD	COSMIC	73.015	Down-regulation
Other_NEK_NEK6_NEK6_ST	P52948	NUP98	Q9HC98	NEK6	S511	N506Y	506	Missense	distal	-5	no	78.783	79.100	EPSD	COSMIC	73.015	Up-regulation
Other_NEK_NEK6_NEK6_ST	P52948	NUP98	Q9HC98	NEK6	S511	Y510H	510	Missense	proximal	-1	no	78.783	79.374	EPSD	COSMIC	73.015	Up-regulation
Other_NEK_NEK6_NEK6_ST	P52948	NUP98	Q9HC98	NEK6	S511	Y510F	510	Missense	proximal	-1	no	78.783	80.363	EPSD	COSMIC	73.015	Up-regulation
Other_NEK_NEK6_NEK6_ST	P52948	NUP98	Q9HC98	NEK6	T536	P538T	538	Missense	proximal	2	no	75.114	72.620	EPSD	COSMIC	73.015	Loss
Other_NEK_NEK6_NEK6_ST	P52948	NUP98	Q9HC98	NEK6	T536	R532I	532	Missense	distal	-4	no	75.114	75.086	EPSD	COSMIC	73.015	Down-regulation
Other_NEK_NEK6_NEK6_ST	P52948	NUP98	Q9HC98	NEK6	T536	L533F	533	Missense	distal	-3	no	75.114	61.978	EPSD	COSMIC	73.015	Loss
Other_NEK_NEK6_NEK6_ST	P52948	NUP98	Q9HC98	NEK6	T536	R532S	532	Missense	distal	-4	no	75.114	75.901	EPSD	COSMIC	73.015	Up-regulation
Other_NEK_NEK6_NEK6_ST	P52948	NUP98	Q9HC98	NEK6	T536	A539V	539	Missense	distal	3	no	75.114	75.162	EPSD	COSMIC	73.015	Up-regulation
Other_NEK_NEK6_NEK6_ST	P52948	NUP98	Q9HC98	NEK6	T568	R561W	561	Missense	distal	-7	no	78.103	77.549	EPSD	COSMIC	73.015	Down-regulation
Other_NEK_NEK6_NEK6_ST	P52948	NUP98	Q9HC98	NEK6	T568	T570K	570	Missense	proximal	2	no	78.103	77.692	EPSD	COSMIC	73.015	Down-regulation
Other_NEK_NEK6_NEK6_ST	P52948	NUP98	Q9HC98	NEK6	T568	G569D	569	Missense	proximal	1	no	78.103	75.173	EPSD	COSMIC	73.015	Down-regulation
Other_NEK_NEK6_NEK6_ST	P52948	NUP98	Q9HC98	NEK6	T568	R561Q	561	Missense	distal	-7	no	78.103	78.221	EPSD	COSMIC	73.015	Up-regulation
Other_NEK_NEK6_NEK6_ST	P52948	NUP98	Q9HC98	NEK6	T568	K563E	563	Missense	distal	-5	no	78.103	78.404	EPSD	COSMIC	73.015	Up-regulation
Other_NEK_NEK6_NEK6_ST	P52948	NUP98	Q9HC98	NEK6	T568	T567R	567	Missense	proximal	-1	no	78.103	79.730	EPSD	COSMIC	73.015	Up-regulation
Other_NEK_NEK6_NEK6_ST	P52948	NUP98	Q9HC98	NEK6	S596	K594T	594	Missense	proximal	-2	no	84.439	77.080	EPSD	COSMIC	73.015	Down-regulation
Other_NEK_NEK6_NEK6_ST	P52948	NUP98	Q9HC98	NEK6	S596	G589A	589	Missense	distal	-7	no	84.439	84.655	EPSD	COSMIC	73.015	Up-regulation
Other_NEK_NEK6_NEK6_ST	P52948	NUP98	Q9HC98	NEK6	S596	I597V	597	Missense	proximal	1	no	84.439	83.213	EPSD	COSMIC	73.015	Down-regulation
Other_NEK_NEK6_NEK6_ST	P52948	NUP98	Q9HC98	NEK6	S608	N606S	606	Missense	proximal	-2	no	110.035	112.500	EPSD	COSMIC	73.015	Up-regulation
Other_NEK_NEK6_NEK6_ST	P52948	NUP98	Q9HC98	NEK6	S608	L610V	610	Missense	proximal	2	no	110.035	111.209	EPSD	COSMIC	73.015	Up-regulation
Other_NEK_NEK6_NEK6_ST	P52948	NUP98	Q9HC98	NEK6	S608	N606I	606	Missense	proximal	-2	no	110.035	102.022	EPSD	COSMIC	73.015	Down-regulation
Other_NEK_NEK6_NEK6_ST	P52948	NUP98	Q9HC98	NEK6	S704	E702G	702	Missense	proximal	-2	no	79.988	88.339	EPSD	COSMIC	73.015	Up-regulation
Other_NEK_NEK6_NEK6_ST	P52948	NUP98	Q9HC98	NEK6	S704	S704C	704	Missense	central	0	yes	79.988	0.000	EPSD	COSMIC	73.015	Loss
Other_NEK_NEK6_NEK6_ST	P52948	NUP98	Q9HC98	NEK6	S704	R698Q	698	Missense	distal	-6	no	79.988	79.974	EPSD	COSMIC	73.015	Down-regulation
Other_NEK_NEK6_NEK6_ST	P52948	NUP98	Q9HC98	NEK6	S704	H711N	711	Missense	distal	7	no	79.988	79.579	EPSD	COSMIC	73.015	Down-regulation
Other_NEK_NEK6_NEK6_ST	P52948	NUP98	Q9HC98	NEK6	S704	H711Y	711	Missense	distal	7	no	79.988	79.594	EPSD	COSMIC	73.015	Down-regulation
Other_NEK_NEK6_NEK6_ST	P52948	NUP98	Q9HC98	NEK6	S704	S704R	704	Missense	central	0	yes	79.988	0.000	EPSD	COSMIC	73.015	Loss
Other_NEK_NEK6_NEK6_ST	P52948	NUP98	Q9HC98	NEK6	S704	S709F	709	Missense	distal	5	no	79.988	79.444	EPSD	COSMIC	73.015	Down-regulation
Other_NEK_NEK6_NEK6_ST	P52948	NUP98	Q9HC98	NEK6	S839	A844S	844	Missense	distal	5	no	111.564	110.999	EPSD	COSMIC	73.015	Down-regulation
Other_NEK_NEK6_NEK6_ST	P52948	NUP98	Q9HC98	NEK6	S839	R842C	842	Missense	distal	3	no	111.564	111.641	EPSD	COSMIC	73.015	Up-regulation
Other_NEK_NEK6_NEK6_ST	P52948	NUP98	Q9HC98	NEK6	S839	R842H	842	Missense	distal	3	no	111.564	111.663	EPSD	COSMIC	73.015	Up-regulation
Other_NEK_NEK6_NEK6_ST	P52948	NUP98	Q9HC98	NEK6	S839	R834S	834	Missense	distal	-5	no	111.564	111.354	EPSD	COSMIC;GDSC;CCLE	73.015	Down-regulation
Other_NEK_NEK6_NEK6_ST	P52948	NUP98	Q9HC98	NEK6	S878	H879R	879	Missense	proximal	1	no	77.278	77.348	EPSD	COSMIC	73.015	Up-regulation
Other_NEK_NEK6_NEK6_ST	P52948	NUP98	Q9HC98	NEK6	S878	Y883H	883	Missense	distal	5	no	77.278	78.198	EPSD	COSMIC	73.015	Up-regulation
Other_NEK_NEK6_NEK6_ST	P52948	NUP98	Q9HC98	NEK6	S888	E894G	894	Missense	distal	6	no	88.049	87.277	EPSD	COSMIC	73.015	Down-regulation
Other_NEK_NEK6_NEK6_ST	P52948	NUP98	Q9HC98	NEK6	S888	Y883H	883	Missense	distal	-5	no	88.049	88.116	EPSD	COSMIC	73.015	Up-regulation
Other_NEK_NEK6_NEK6_ST	P52948	NUP98	Q9HC98	NEK6	S888	E890K	890	Missense	proximal	2	no	88.049	87.945	EPSD	COSMIC	73.015	Down-regulation
Other_NEK_NEK6_NEK6_ST	P52948	NUP98	Q9HC98	NEK6	S913	T916M	916	Missense	distal	3	no	88.721	88.763	EPSD	COSMIC	73.015	Up-regulation
Other_NEK_NEK6_NEK6_ST	P52948	NUP98	Q9HC98	NEK6	S913	P917L	917	Missense	distal	4	no	88.721	88.287	EPSD	COSMIC	73.015	Down-regulation
Other_NEK_NEK6_NEK6_ST	P52948	NUP98	Q9HC98	NEK6	S913	S913I	913	Missense	central	0	yes	88.721	0.000	EPSD	COSMIC	73.015	Loss
Other_NEK_NEK6_NEK6_ST	P52948	NUP98	Q9HC98	NEK6	S913	A912V	912	Missense	proximal	-1	no	88.721	88.069	EPSD	COSMIC	73.015	Down-regulation
Other_NEK_NEK6_NEK6_ST	P52948	NUP98	Q9HC98	NEK6	S966	E969Q	969	Missense	distal	3	no	86.927	86.947	EPSD	COSMIC	73.015	Up-regulation
Other_NEK_NEK6_NEK6_ST	P52948	NUP98	Q9HC98	NEK6	S966	E969D	969	Missense	distal	3	no	86.927	86.826	EPSD	COSMIC	73.015	Down-regulation
Other_NEK_NEK6_NEK6_ST	P52948	NUP98	Q9HC98	NEK6	S966	L959M	959	Missense	distal	-7	no	86.927	86.848	EPSD	COSMIC	73.015	Down-regulation
Other_NEK_NEK6_NEK6_ST	P52948	NUP98	Q9HC98	NEK6	S966	P973L	973	Missense	distal	7	no	86.927	87.947	EPSD	COSMIC	73.015	Up-regulation
Other_NEK_NEK6_NEK6_ST	P52948	NUP98	Q9HC98	NEK6	S966	D970E	970	Missense	distal	4	no	86.927	84.167	EPSD	COSMIC	73.015	Down-regulation
Other_NEK_NEK6_NEK6_ST	P52948	NUP98	Q9HC98	NEK6	S1051	G1047W	1047	Missense	distal	-4	no	85.490	82.860	EPSD	COSMIC	73.015	Down-regulation
Other_NEK_NEK6_NEK6_ST	P52948	NUP98	Q9HC98	NEK6	S1051	T1054K	1054	Missense	distal	3	no	85.490	85.437	EPSD	COSMIC	73.015	Down-regulation
Other_NEK_NEK6_NEK6_ST	P52948	NUP98	Q9HC98	NEK6	S1051	K1052T	1052	Missense	proximal	1	no	85.490	87.112	EPSD	COSMIC	73.015	Up-regulation
Other_NEK_NEK6_NEK6_ST	P52948	NUP98	Q9HC98	NEK6	S1051	G1046C	1046	Missense	distal	-5	no	85.490	85.940	EPSD	COSMIC	73.015	Up-regulation
Other_NEK_NEK6_NEK6_ST	P52948	NUP98	Q9HC98	NEK6	S1062	V1063F	1063	Missense	proximal	1	no	90.290	91.526	EPSD	COSMIC	73.015	Up-regulation
Other_NEK_NEK6_NEK6_ST	P52948	NUP98	Q9HC98	NEK6	S1062	L1059F	1059	Missense	distal	-3	no	90.290	77.154	EPSD	COSMIC	73.015	Down-regulation
Other_NEK_NEK6_NEK6_ST	P52948	NUP98	Q9HC98	NEK6	S1064	V1063F	1063	Missense	proximal	-1	no	89.758	89.513	EPSD	COSMIC	73.015	Down-regulation
Other_NEK_NEK6_NEK6_ST	P52948	NUP98	Q9HC98	NEK6	S1064	L1059F	1059	Missense	distal	-5	no	89.758	89.838	EPSD	COSMIC	73.015	Up-regulation
Other_NEK_NEK6_NEK6_ST	P52948	NUP98	Q9HC98	NEK6	S1064	P1071L	1071	Missense	distal	7	no	89.758	90.777	EPSD	COSMIC	73.015	Up-regulation
Other_NEK_NEK6_NEK6_ST	P52948	NUP98	Q9HC98	NEK6	S1064	P1071H	1071	Missense	distal	7	no	89.758	90.809	EPSD	COSMIC	73.015	Up-regulation
Other_NEK_NEK6_NEK6_ST	P52948	NUP98	Q9HC98	NEK6	S1083	P1088H	1088	Missense	distal	5	no	86.769	87.326	EPSD	COSMIC	73.015	Up-regulation
Other_NEK_NEK6_NEK6_ST	P52948	NUP98	Q9HC98	NEK6	S1083	P1088S	1088	Missense	distal	5	no	86.769	88.346	EPSD	COSMIC	73.015	Up-regulation
Other_NEK_NEK6_NEK6_ST	P52948	NUP98	Q9HC98	NEK6	S1192	T1190A	1190	Missense	proximal	-2	no	90.650	93.226	EPSD	COSMIC	73.015	Up-regulation
Other_NEK_NEK6_NEK6_ST	P52948	NUP98	Q9HC98	NEK6	S1192	K1195R	1195	Missense	distal	3	no	90.650	90.719	EPSD	COSMIC	73.015	Up-regulation
Other_NEK_NEK6_NEK6_ST	P52948	NUP98	Q9HC98	NEK6	T1313	T1315R	1315	Missense	proximal	2	no	72.138	74.055	EPSD	COSMIC	73.015	Gain
Other_NEK_NEK6_NEK6_ST	P52948	NUP98	Q9HC98	NEK6	T1313	T1315I	1315	Missense	proximal	2	no	72.138	75.403	EPSD	COSMIC	73.015	Gain
Other_NEK_NEK6_NEK6_ST	P52948	NUP98	Q9HC98	NEK6	S1368	R1372Q	1372	Missense	distal	4	no	73.234	77.309	EPSD	COSMIC	73.015	Up-regulation
Other_NEK_NEK6_NEK6_ST	P52948	NUP98	Q9HC98	NEK6	S1368	L1375I	1375	Missense	distal	7	no	73.234	73.772	EPSD	COSMIC	73.015	Up-regulation
Other_NEK_NEK6_NEK6_ST	P52948	NUP98	Q9HC98	NEK6	S1368	S1368I	1368	Missense	central	0	yes	73.234	0.000	EPSD	COSMIC	73.015	Loss
Other_NEK_NEK6_NEK6_ST	P52948	NUP98	Q9HC98	NEK6	S1368	G1367C	1367	Missense	proximal	-1	no	73.234	75.997	EPSD	COSMIC	73.015	Up-regulation
Other_NEK_NEK6_NEK6_ST	P52948	NUP98	Q9HC98	NEK6	S1368	R1372L	1372	Missense	distal	4	no	73.234	75.034	EPSD	COSMIC	73.015	Up-regulation
Other_NEK_NEK6_NEK6_ST	P52948	NUP98	Q9HC98	NEK6	S1368	S1368G	1368	Missense	central	0	yes	73.234	0.000	EPSD	COSMIC	73.015	Loss
Other_NEK_NEK6_NEK6_ST	P52948	NUP98	Q9HC98	NEK6	S1368	Q1369L	1369	Missense	proximal	1	no	73.234	73.870	EPSD	COSMIC	73.015	Up-regulation
Other_NEK_NEK6_NEK6_ST	P52948	NUP98	Q9HC98	NEK6	S1469	L1471M	1471	Missense	proximal	2	no	79.694	82.559	EPSD	COSMIC	73.015	Up-regulation
Other_NEK_NEK6_NEK6_ST	P52948	NUP98	Q9HC98	NEK6	S1469	P1466T	1466	Missense	distal	-3	no	79.694	35.943	EPSD	COSMIC	73.015	Loss
Other_NEK_NEK6_NEK6_ST	P52948	NUP98	Q9HC98	NEK6	S1469	P1468S	1468	Missense	proximal	-1	no	79.694	82.625	EPSD	COSMIC	73.015	Up-regulation
Other_NEK_NEK6_NEK6_ST	P52948	NUP98	Q9HC98	NEK6	S1469	L1467R	1467	Missense	proximal	-2	no	79.694	80.878	EPSD	COSMIC	73.015	Up-regulation
Other_NEK_NEK6_NEK6_ST	P52948	NUP98	Q9HC98	NEK6	S1469	G1475V	1475	Missense	distal	6	no	79.694	80.604	EPSD	COSMIC	73.015	Up-regulation
Other_NEK_NEK6_NEK6_ST	P52948	NUP98	Q9HC98	NEK6	S1474	L1471M	1471	Missense	distal	-3	no	85.584	-3.418	EPSD	COSMIC	73.015	Loss
Other_NEK_NEK6_NEK6_ST	P52948	NUP98	Q9HC98	NEK6	S1474	P1468S	1468	Missense	distal	-6	no	85.584	85.419	EPSD	COSMIC	73.015	Down-regulation
Other_NEK_NEK6_NEK6_ST	P52948	NUP98	Q9HC98	NEK6	S1474	L1467R	1467	Missense	distal	-7	no	85.584	85.700	EPSD	COSMIC	73.015	Up-regulation
Other_NEK_NEK6_NEK6_ST	P52948	NUP98	Q9HC98	NEK6	S1474	E1481A	1481	Missense	distal	7	no	85.584	85.758	EPSD	COSMIC	73.015	Up-regulation
Other_NEK_NEK6_NEK6_ST	P52948	NUP98	Q9HC98	NEK6	S1474	G1475V	1475	Missense	proximal	1	no	85.584	84.899	EPSD	COSMIC	73.015	Down-regulation
Other_NEK_NEK6_NEK6_ST	P52948	NUP98	Q9HC98	NEK6	S1745	R1750H	1750	Missense	distal	5	no	75.489	74.763	EPSD	COSMIC	73.015	Down-regulation
Other_NEK_NEK6_NEK6_ST	P52948	NUP98	Q9HC98	NEK6	S1745	R1750C	1750	Missense	distal	5	no	75.489	74.072	EPSD	COSMIC	73.015	Down-regulation
Other_NEK_NEK6_NEK6_ST	P52948	NUP98	Q9HC98	NEK6	S1745	A1748T	1748	Missense	distal	3	no	75.489	75.471	EPSD	COSMIC	73.015	Down-regulation
Other_NEK_NEK6_NEK6_ST	P52948	NUP98	Q9HC98	NEK6	S1745	L1742P	1742	Missense	distal	-3	no	75.489	69.056	EPSD	COSMIC	73.015	Loss
Other_NEK_NEK6_NEK6_ST	P52948	NUP98	Q9HC98	NEK6	S1807	R1802C	1802	Missense	distal	-5	no	76.012	76.207	EPSD	COSMIC	73.015	Up-regulation
Other_NEK_NEK6_NEK6_ST	P52948	NUP98	Q9HC98	NEK6	S1807	S1807F	1807	Missense	central	0	yes	76.012	0.000	EPSD	COSMIC	73.015	Loss
Other_NEK_NEK6_NEK6_ST	P52948	NUP98	Q9HC98	NEK6	S1807	R1810G	1810	Missense	distal	3	no	76.012	76.143	EPSD	COSMIC	73.015	Up-regulation
Other_NEK_NEK6_NEK6_ST	P52732	KIF11	Q9HC98	NEK6	S75	D80Y	80	Missense	distal	5	no	76.268	70.275	EPSD	COSMIC	73.015	Loss
Other_NEK_NEK6_NEK6_ST	P52732	KIF11	Q9HC98	NEK6	S323	R327H	327	Missense	distal	4	no	81.545	82.463	EPSD	COSMIC	73.015	Up-regulation
Other_NEK_NEK6_NEK6_ST	P52732	KIF11	Q9HC98	NEK6	S965	M960L	960	Missense	distal	-5	no	81.036	81.121	EPSD	COSMIC	73.015	Up-regulation
Other_NEK_NEK6_NEK6_ST	P52732	KIF11	Q9HC98	NEK6	S1033	E1037D	1037	Missense	distal	4	no	119.019	121.779	PhosphoSitePlus	COSMIC	73.015	Up-regulation
Other_NEK_NEK6_NEK6_ST	P50613	CDK7	Q9HC98	NEK6	T110	S106I	106	Missense	distal	-4	no	82.249	81.435	EPSD	COSMIC	73.015	Down-regulation
Other_NEK_NEK6_NEK6_ST	P50613	CDK7	Q9HC98	NEK6	S112	S106I	106	Missense	distal	-6	no	87.819	87.716	EPSD	COSMIC	73.015	Down-regulation
Other_NEK_NEK6_NEK6_ST	P50613	CDK7	Q9HC98	NEK6	S161	S161F	161	Missense	central	0	yes	119.091	0.000	PhosphoSitePlus	COSMIC	73.015	Loss
Other_NEK_NEK6_NEK6_ST	P50613	CDK7	Q9HC98	NEK6	S161	G163W	163	Missense	proximal	2	no	119.091	121.189	PhosphoSitePlus	COSMIC	73.015	Up-regulation
Other_NEK_NEK6_NEK6_ST	P50613	CDK7	Q9HC98	NEK6	S161	A154V	154	Missense	distal	-7	no	119.091	118.918	PhosphoSitePlus	COSMIC	73.015	Down-regulation
Other_NEK_NEK6_NEK6_ST	P50613	CDK7	Q9HC98	NEK6	S161	S161Y	161	Missense	central	0	yes	119.091	0.000	PhosphoSitePlus	COSMIC	73.015	Loss
Other_NEK_NEK6_NEK6_ST	P50613	CDK7	Q9HC98	NEK6	S161	A159D	159	Missense	proximal	-2	no	119.091	122.441	PhosphoSitePlus	COSMIC	73.015	Up-regulation
Other_NEK_NEK6_NEK6_ST	P50613	CDK7	Q9HC98	NEK6	S164	S161F	161	Missense	distal	-3	no	-13.957	75.090	EPSD	COSMIC	73.015	Gain
Other_NEK_NEK6_NEK6_ST	P50613	CDK7	Q9HC98	NEK6	S217	G215E	215	Missense	proximal	-2	no	80.732	72.380	EPSD	COSMIC	73.015	Loss
Other_NEK_NEK6_NEK6_ST	P50613	CDK7	Q9HC98	NEK6	S217	D216N	216	Missense	proximal	-1	no	80.732	79.608	EPSD	COSMIC;GDSC;CCLE	73.015	Down-regulation
Other_NEK_NEK6_NEK6_ST	P50613	CDK7	Q9HC98	NEK6	S217	V210D	210	Missense	distal	-7	no	80.732	81.102	EPSD	COSMIC	73.015	Up-regulation
Other_NEK_NEK6_NEK6_ST	P50613	CDK7	Q9HC98	NEK6	T316	N311S	311	Missense	distal	-5	no	79.516	79.612	EPSD	COSMIC	73.015	Up-regulation
Other_NEK_NEK6_NEK6_ST	P50613	CDK7	Q9HC98	NEK6	T316	K318N	318	Missense	proximal	2	no	79.516	81.675	EPSD	COSMIC	73.015	Up-regulation
Other_NEK_NEK6_NEK6_ST	P50613	CDK7	Q9HC98	NEK6	T316	T316A	316	Missense	central	0	yes	79.516	0.000	EPSD	COSMIC	73.015	Loss
Other_NEK_NEK6_NEK6_ST	P50613	CDK7	Q9HC98	NEK6	T316	C312R	312	Missense	distal	-4	no	79.516	80.456	EPSD	COSMIC	73.015	Up-regulation
Other_NEK_NEK6_NEK6_ST	P50613	CDK7	Q9HC98	NEK6	T316	N322I	322	Missense	distal	6	no	79.516	79.135	EPSD	COSMIC	73.015	Down-regulation
Other_NEK_NEK6_NEK6_ST	P40763	STAT3	Q9HC98	NEK6	T433	S429F	429	Missense	distal	-4	no	79.952	78.662	EPSD	COSMIC	73.015	Down-regulation
Other_NEK_NEK6_NEK6_ST	P40763	STAT3	Q9HC98	NEK6	T433	T433I	433	Missense	central	0	yes	79.952	0.000	EPSD	COSMIC	73.015	Loss
Other_NEK_NEK6_NEK6_ST	P40763	STAT3	Q9HC98	NEK6	T433	L430Q	430	Missense	distal	-3	no	79.952	14.871	EPSD	COSMIC	73.015	Loss
Other_NEK_NEK6_NEK6_ST	P40763	STAT3	Q9HC98	NEK6	S727	D723N	723	Missense	distal	-4	no	112.082	111.614	PhosphoSitePlus	COSMIC	73.015	Down-regulation
Other_NEK_NEK6_NEK6_ST	Q05586	GRIN1	Q9HC98	NEK6	T122	P117L	117	Missense	distal	-5	no	83.571	83.624	EPSD	COSMIC	73.015	Up-regulation
Other_NEK_NEK6_NEK6_ST	Q05586	GRIN1	Q9HC98	NEK6	T122	I116M	116	Missense	distal	-6	no	83.571	83.599	EPSD	COSMIC;GDSC;CCLE	73.015	Up-regulation
Other_NEK_NEK6_NEK6_ST	Q05586	GRIN1	Q9HC98	NEK6	T122	R124S	124	Missense	proximal	2	no	83.571	82.655	EPSD	COSMIC	73.015	Down-regulation
Other_NEK_NEK6_NEK6_ST	Q05586	GRIN1	Q9HC98	NEK6	T122	T122A	122	Missense	central	0	yes	83.571	0.000	EPSD	COSMIC	73.015	Loss
Other_NEK_NEK6_NEK6_ST	Q05586	GRIN1	Q9HC98	NEK6	T442	P444R	444	Missense	proximal	2	no	79.464	78.887	EPSD	COSMIC	73.015	Down-regulation
Other_NEK_NEK6_NEK6_ST	Q05586	GRIN1	Q9HC98	NEK6	S775	V772L	772	Missense	distal	-3	no	38.427	93.664	EPSD	COSMIC	73.015	Gain
Other_NEK_NEK6_NEK6_ST	Q05586	GRIN1	Q9HC98	NEK6	S890	L887M	887	Missense	distal	-3	no	109.486	20.484	PhosphoSitePlus	COSMIC	73.015	Loss
Other_NEK_NEK6_NEK6_ST	Q05586	GRIN1	Q9HC98	NEK6	S890	A888T	888	Missense	proximal	-2	no	109.486	106.910	PhosphoSitePlus	COSMIC	73.015	Down-regulation
Other_NEK_NEK6_NEK6_ST	Q05586	GRIN1	Q9HC98	NEK6	S890	R894H	894	Missense	distal	4	no	109.486	110.404	PhosphoSitePlus	COSMIC;GDSC	73.015	Up-regulation
Other_NEK_NEK6_NEK6_ST	Q05586	GRIN1	Q9HC98	NEK6	S890	R894C	894	Missense	distal	4	no	109.486	110.101	PhosphoSitePlus	COSMIC	73.015	Up-regulation
Other_NEK_NEK6_NEK6_ST	P0DMV8	HSPA1A	Q9HC98	NEK6	S608	G615C	615	Missense	distal	7	no	74.623	75.198	EPSD	COSMIC	73.015	Up-regulation
Other_NEK_NEK6_NEK6_ST	P0DMV8	HSPA1A	Q9HC98	NEK6	S608	Q612K	612	Missense	distal	4	no	74.623	73.252	EPSD	COSMIC	73.015	Down-regulation
CK1_CK1_CK1-A_CSNK1A1_ST	P02730	SLC4A1	P48729	CSNK1A1	S303	S310F	310	Missense	distal	7	no	20.723	20.910	PhosphoSitePlus;EPSD	COSMIC	20.411	Up-regulation
CK1_CK1_CK1-A_CSNK1A1_ST	P02730	SLC4A1	P48729	CSNK1A1	S303	G305E	305	Missense	proximal	2	no	20.723	20.328	PhosphoSitePlus;EPSD	COSMIC	20.411	Loss
CK1_CK1_CK1-A_CSNK1A1_ST	P02730	SLC4A1	P48729	CSNK1A1	S303	G305R	305	Missense	proximal	2	no	20.723	19.771	PhosphoSitePlus;EPSD	COSMIC;CCLE	20.411	Loss
CK1_CK1_CK1-A_CSNK1A1_ST	P02730	SLC4A1	P48729	CSNK1A1	S303	S303R	303	Missense	central	0	yes	20.723	0.000	PhosphoSitePlus;EPSD	COSMIC	20.411	Loss
CK1_CK1_CK1-A_CSNK1A1_ST	P02730	SLC4A1	P48729	CSNK1A1	S402	V409I	409	Missense	distal	7	no	22.377	22.088	EPSD	COSMIC;GDSC;CCLE	20.411	Down-regulation
CK1_CK1_CK1-A_CSNK1A1_ST	P02730	SLC4A1	P48729	CSNK1A1	S402	I397T	397	Missense	distal	-5	no	22.377	21.918	EPSD	COSMIC	20.411	Down-regulation
CK1_CK1_CK1-A_CSNK1A1_ST	P02730	SLC4A1	P48729	CSNK1A1	S402	L406M	406	Missense	distal	4	no	22.377	22.235	EPSD	COSMIC	20.411	Down-regulation
CK1_CK1_CK1-A_CSNK1A1_ST	P55316	FOXG1	P48729	CSNK1A1	S228	L235F	235	Missense	distal	7	no	23.055	23.207	EPSD	COSMIC	20.411	Up-regulation
CK1_CK1_CK1-A_CSNK1A1_ST	P55316	FOXG1	P48729	CSNK1A1	S228	S228C	228	Missense	central	0	yes	23.055	0.000	EPSD	COSMIC	20.411	Loss
CK1_CK1_CK1-A_CSNK1A1_ST	Q13148	TARDBP	P48729	CSNK1A1	S91	D86Y	86	Missense	distal	-5	no	21.307	19.282	EPSD;PhosphoSitePlus	COSMIC	20.411	Loss
CK1_CK1_CK1-A_CSNK1A1_ST	Q13148	TARDBP	P48729	CSNK1A1	S91	M85V	85	Missense	distal	-6	no	21.307	20.279	EPSD;PhosphoSitePlus	COSMIC	20.411	Loss
CK1_CK1_CK1-A_CSNK1A1_ST	Q13148	TARDBP	P48729	CSNK1A1	S183	Q182R	182	Missense	proximal	-1	no	23.255	22.259	EPSD;PhosphoSitePlus	COSMIC	20.411	Down-regulation
CK1_CK1_CK1-A_CSNK1A1_ST	Q13148	TARDBP	P48729	CSNK1A1	S183	E186K	186	Missense	distal	3	no	23.255	19.125	EPSD;PhosphoSitePlus	COSMIC	20.411	Loss
CK1_CK1_CK1-A_CSNK1A1_ST	Q13148	TARDBP	P48729	CSNK1A1	S242	L248S	248	Missense	distal	6	no	26.009	26.148	EPSD;PhosphoSitePlus	COSMIC	20.411	Up-regulation
CK1_CK1_CK1-A_CSNK1A1_ST	Q13148	TARDBP	P48729	CSNK1A1	S258	S258Y	258	Missense	central	0	yes	20.701	0.000	EPSD	COSMIC	20.411	Loss
CK1_CK1_CK1-A_CSNK1A1_ST	Q13148	TARDBP	P48729	CSNK1A1	S342	G338D	338	Missense	distal	-4	no	23.046	23.875	EPSD;PhosphoSitePlus	COSMIC	20.411	Up-regulation
CK1_CK1_CK1-A_CSNK1A1_ST	Q13148	TARDBP	P48729	CSNK1A1	S350	Q356K	356	Missense	distal	6	no	23.470	23.362	EPSD;PhosphoSitePlus	COSMIC	20.411	Down-regulation
CK1_CK1_CK1-A_CSNK1A1_ST	Q13148	TARDBP	P48729	CSNK1A1	S350	N355S	355	Missense	distal	5	no	23.470	23.049	EPSD;PhosphoSitePlus	COSMIC	20.411	Down-regulation
CK1_CK1_CK1-A_CSNK1A1_ST	Q13148	TARDBP	P48729	CSNK1A1	S369	N364K	364	Missense	distal	-5	no	20.804	19.716	EPSD;PhosphoSitePlus	COSMIC	20.411	Loss
CK1_CK1_CK1-A_CSNK1A1_ST	Q13148	TARDBP	P48729	CSNK1A1	S369	G368C	368	Missense	proximal	-1	no	20.804	18.926	EPSD;PhosphoSitePlus	COSMIC	20.411	Loss
CK1_CK1_CK1-A_CSNK1A1_ST	Q13148	TARDBP	P48729	CSNK1A1	S369	E362V	362	Missense	distal	-7	no	20.804	18.546	EPSD;PhosphoSitePlus	COSMIC	20.411	Loss
CK1_CK1_CK1-A_CSNK1A1_ST	Q13148	TARDBP	P48729	CSNK1A1	S375	G368C	368	Missense	distal	-7	no	22.243	20.535	EPSD;PhosphoSitePlus	COSMIC	20.411	Down-regulation
CK1_CK1_CK1-A_CSNK1A1_ST	Q13148	TARDBP	P48729	CSNK1A1	S387	N390D	390	Missense	distal	3	no	21.016	24.215	EPSD;PhosphoSitePlus	COSMIC	20.411	Up-regulation
CK1_CK1_CK1-A_CSNK1A1_ST	Q13148	TARDBP	P48729	CSNK1A1	S389	N390D	390	Missense	proximal	1	no	24.096	24.326	EPSD;PhosphoSitePlus	COSMIC	20.411	Up-regulation
CK1_CK1_CK1-A_CSNK1A1_ST	Q13148	TARDBP	P48729	CSNK1A1	S393	N390D	390	Missense	distal	-3	no	19.988	25.268	EPSD;PhosphoSitePlus	COSMIC	20.411	Gain
CK1_CK1_CK1-A_CSNK1A1_ST	Q13148	TARDBP	P48729	CSNK1A1	S395	N390D	390	Missense	distal	-5	no	20.250	20.500	EPSD;PhosphoSitePlus	COSMIC	20.411	Gain
CK1_CK1_CK1-A_CSNK1A1_ST	P98177	FOXO4	P48729	CSNK1A1	S111	I110V	110	Missense	proximal	-1	no	20.785	19.295	EPSD	COSMIC	20.411	Loss
CK1_CK1_CK1-A_CSNK1A1_ST	P98177	FOXO4	P48729	CSNK1A1	S111	S116N	116	Missense	distal	5	no	20.785	21.206	EPSD	COSMIC	20.411	Up-regulation
CK1_CK1_CK1-A_CSNK1A1_ST	P98177	FOXO4	P48729	CSNK1A1	S111	P118L	118	Missense	distal	7	no	20.785	20.633	EPSD	COSMIC	20.411	Down-regulation
CK1_CK1_CK1-A_CSNK1A1_ST	P98177	FOXO4	P48729	CSNK1A1	S153	N157I	157	Missense	distal	4	no	23.864	23.965	EPSD	COSMIC	20.411	Up-regulation
CK1_CK1_CK1-A_CSNK1A1_ST	P98177	FOXO4	P48729	CSNK1A1	S197	A190G	190	Missense	distal	-7	no	20.505	21.035	EPSD	COSMIC	20.411	Up-regulation
CK1_CK1_CK1-A_CSNK1A1_ST	P98177	FOXO4	P48729	CSNK1A1	S197	R194L	194	Missense	distal	-3	no	20.505	18.137	EPSD	COSMIC	20.411	Loss
CK1_CK1_CK1-A_CSNK1A1_ST	P98177	FOXO4	P48729	CSNK1A1	S197	A196T	196	Missense	proximal	-1	no	20.505	20.239	EPSD	COSMIC	20.411	Loss
CK1_CK1_CK1-A_CSNK1A1_ST	P98177	FOXO4	P48729	CSNK1A1	S197	A196V	196	Missense	proximal	-1	no	20.505	19.903	EPSD	COSMIC	20.411	Loss
CK1_CK1_CK1-A_CSNK1A1_ST	P98177	FOXO4	P48729	CSNK1A1	S197	R193S	193	Missense	distal	-4	no	20.505	22.538	EPSD	COSMIC	20.411	Up-regulation
CK1_CK1_CK1-A_CSNK1A1_ST	P98177	FOXO4	P48729	CSNK1A1	S197	D199N	199	Missense	proximal	2	no	20.505	19.312	EPSD	COSMIC	20.411	Loss
CK1_CK1_CK1-A_CSNK1A1_ST	P98177	FOXO4	P48729	CSNK1A1	S265	P258S	258	Missense	distal	-7	no	24.580	25.246	EPSD;PhosphoSitePlus	COSMIC	20.411	Up-regulation
CK1_CK1_CK1-A_CSNK1A1_ST	P98177	FOXO4	P48729	CSNK1A1	S265	T269N	269	Missense	distal	4	no	24.580	24.536	EPSD;PhosphoSitePlus	COSMIC	20.411	Down-regulation
CK1_CK1_CK1-A_CSNK1A1_ST	P98177	FOXO4	P48729	CSNK1A1	S268	T269N	269	Missense	proximal	1	no	23.171	23.106	PhosphoSitePlus;EPSD	COSMIC	20.411	Down-regulation
CK1_CK1_CK1-A_CSNK1A1_ST	P98177	FOXO4	P48729	CSNK1A1	S317	R321Q	321	Missense	distal	4	no	22.231	22.133	EPSD	COSMIC	20.411	Down-regulation
CK1_CK1_CK1-A_CSNK1A1_ST	P98177	FOXO4	P48729	CSNK1A1	S317	L312P	312	Missense	distal	-5	no	22.231	22.427	EPSD	COSMIC	20.411	Up-regulation
CK1_CK1_CK1-A_CSNK1A1_ST	P98177	FOXO4	P48729	CSNK1A1	S320	R321Q	321	Missense	proximal	1	no	20.175	20.516	EPSD	COSMIC	20.411	Gain
CK1_CK1_CK1-A_CSNK1A1_ST	O15151	MDM4	P48729	CSNK1A1	S289	V296I	296	Missense	distal	7	no	27.589	27.300	PhosphoSitePlus	COSMIC	20.411	Down-regulation
CK1_CK1_CK1-A_CSNK1A1_ST	O15151	MDM4	P48729	CSNK1A1	S289	L284P	284	Missense	distal	-5	no	27.589	27.785	PhosphoSitePlus	COSMIC	20.411	Up-regulation
CK1_CK1_CK1-A_CSNK1A1_ST	O15151	MDM4	P48729	CSNK1A1	S289	D286N	286	Missense	distal	-3	no	27.589	22.309	PhosphoSitePlus	COSMIC	20.411	Down-regulation
CK1_CK1_CK1-A_CSNK1A1_ST	O15151	MDM4	P48729	CSNK1A1	S289	S289F	289	Missense	central	0	yes	27.589	0.000	PhosphoSitePlus	COSMIC	20.411	Loss
CK1_CK1_CK1-A_CSNK1A1_ST	Q9Y2W7	KCNIP3	P48729	CSNK1A1	S14	G20W	20	Missense	distal	6	no	21.452	20.747	EPSD	COSMIC	20.411	Down-regulation
CK1_CK1_CK1-A_CSNK1A1_ST	Q9Y2W7	KCNIP3	P48729	CSNK1A1	S14	K9T	9	Missense	distal	-5	no	21.452	22.080	EPSD	COSMIC	20.411	Up-regulation
CK1_CK1_CK1-A_CSNK1A1_ST	Q9Y2W7	KCNIP3	P48729	CSNK1A1	S14	L19V	19	Missense	distal	5	no	21.452	21.490	EPSD	COSMIC	20.411	Up-regulation
CK1_CK1_CK1-A_CSNK1A1_ST	Q9Y2W7	KCNIP3	P48729	CSNK1A1	S14	G13D	13	Missense	proximal	-1	no	21.452	21.179	EPSD	COSMIC	20.411	Down-regulation
CK1_CK1_CK1-A_CSNK1A1_ST	Q9Y2W7	KCNIP3	P48729	CSNK1A1	S63	A56S	56	Missense	distal	-7	no	21.449	20.926	PhosphoSitePlus	COSMIC	20.411	Down-regulation
CK1_CK1_CK1-A_CSNK1A1_ST	Q9Y2W7	KCNIP3	P48729	CSNK1A1	S63	S70C	70	Missense	distal	7	no	21.449	21.602	PhosphoSitePlus	COSMIC	20.411	Up-regulation
CK1_CK1_CK1-A_CSNK1A1_ST	Q9Y2W7	KCNIP3	P48729	CSNK1A1	S63	E68K	68	Missense	distal	5	no	21.449	21.894	PhosphoSitePlus	COSMIC;GDSC;CCLE	20.411	Up-regulation
CK1_CK1_CK1-A_CSNK1A1_ST	Q9Y2W7	KCNIP3	P48729	CSNK1A1	S63	S60P	60	Missense	distal	-3	no	21.449	15.262	PhosphoSitePlus	COSMIC	20.411	Loss
CK1_CK1_CK1-A_CSNK1A1_ST	Q9Y2W7	KCNIP3	P48729	CSNK1A1	S63	L69P	69	Missense	distal	6	no	21.449	21.363	PhosphoSitePlus	COSMIC	20.411	Down-regulation
CK1_CK1_CK1-A_CSNK1A1_ST	Q9BXL7	CARD11	P48729	CSNK1A1	S466	A465G	465	Missense	proximal	-1	no	19.685	20.514	EPSD	COSMIC	20.411	Gain
CK1_CK1_CK1-A_CSNK1A1_ST	Q9BXL7	CARD11	P48729	CSNK1A1	S541	T545P	545	Missense	distal	4	no	22.394	22.392	EPSD	COSMIC	20.411	Down-regulation
CK1_CK1_CK1-A_CSNK1A1_ST	Q9BXL7	CARD11	P48729	CSNK1A1	S541	S538F	538	Missense	distal	-3	no	22.394	16.742	EPSD	COSMIC	20.411	Loss
CK1_CK1_CK1-A_CSNK1A1_ST	Q9BXL7	CARD11	P48729	CSNK1A1	S541	G540E	540	Missense	proximal	-1	no	22.394	22.751	EPSD	COSMIC	20.411	Up-regulation
CK1_CK1_CK1-A_CSNK1A1_ST	Q9BXL7	CARD11	P48729	CSNK1A1	S541	G540R	540	Missense	proximal	-1	no	22.394	21.231	EPSD	COSMIC;GDSC	20.411	Down-regulation
CK1_CK1_CK1-A_CSNK1A1_ST	Q9BXL7	CARD11	P48729	CSNK1A1	S559	R557S	557	Missense	proximal	-2	no	20.325	21.415	EPSD	COSMIC	20.411	Gain
CK1_CK1_CK1-A_CSNK1A1_ST	Q9BXL7	CARD11	P48729	CSNK1A1	S559	P554S	554	Missense	distal	-5	no	20.325	20.757	EPSD	COSMIC	20.411	Gain
CK1_CK1_CK1-A_CSNK1A1_ST	Q9BXL7	CARD11	P48729	CSNK1A1	S559	E566K	566	Missense	distal	7	no	20.325	20.454	EPSD	COSMIC	20.411	Gain
CK1_CK1_CK1-A_CSNK1A1_ST	Q9BXL7	CARD11	P48729	CSNK1A1	S559	P553T	553	Missense	distal	-6	no	20.325	20.625	EPSD	COSMIC	20.411	Gain
CK1_CK1_CK1-A_CSNK1A1_ST	Q9BXL7	CARD11	P48729	CSNK1A1	S559	A565T	565	Missense	distal	6	no	20.325	20.579	EPSD	COSMIC	20.411	Gain
CK1_CK1_CK1-A_CSNK1A1_ST	Q9BXL7	CARD11	P48729	CSNK1A1	S562	R557S	557	Missense	distal	-5	no	19.878	20.749	EPSD	COSMIC	20.411	Gain
CK1_CK1_CK1-A_CSNK1A1_ST	Q9BXL7	CARD11	P48729	CSNK1A1	S585	P582S	582	Missense	distal	-3	no	14.854	21.041	EPSD	COSMIC	20.411	Gain
CK1_CK1_CK1-A_CSNK1A1_ST	Q9BXL7	CARD11	P48729	CSNK1A1	S593	F596V	596	Missense	distal	3	no	20.489	20.365	EPSD	COSMIC	20.411	Loss
CK1_CK1_CK1-A_CSNK1A1_ST	Q9BXL7	CARD11	P48729	CSNK1A1	S593	D590Y	590	Missense	distal	-3	no	20.489	14.143	EPSD	COSMIC	20.411	Loss
CK1_CK1_CK1-A_CSNK1A1_ST	Q9BXL7	CARD11	P48729	CSNK1A1	S593	G595R	595	Missense	proximal	2	no	20.489	19.537	EPSD	COSMIC	20.411	Loss
CK1_CK1_CK1-A_CSNK1A1_ST	Q9BXL7	CARD11	P48729	CSNK1A1	S593	S593G	593	Missense	central	0	yes	20.489	0.000	EPSD	COSMIC	20.411	Loss
CK1_CK1_CK1-A_CSNK1A1_ST	Q9BXL7	CARD11	P48729	CSNK1A1	S618	S618C	618	Missense	central	0	yes	21.130	0.000	EPSD	COSMIC	20.411	Loss
CK1_CK1_CK1-A_CSNK1A1_ST	Q9BXL7	CARD11	P48729	CSNK1A1	S618	S618F	618	Missense	central	0	yes	21.130	0.000	EPSD	COSMIC	20.411	Loss
CK1_CK1_CK1-A_CSNK1A1_ST	Q9BXL7	CARD11	P48729	CSNK1A1	S618	S615F	615	Missense	distal	-3	no	21.130	15.478	EPSD	COSMIC	20.411	Loss
CK1_CK1_CK1-A_CSNK1A1_ST	Q9BXL7	CARD11	P48729	CSNK1A1	S618	S622H	622	Missense	distal	4	no	21.130	21.028	EPSD	COSMIC	20.411	Down-regulation
CK1_CK1_CK1-A_CSNK1A1_ST	Q9BXL7	CARD11	P48729	CSNK1A1	S618	S622F	622	Missense	distal	4	no	21.130	21.044	EPSD	COSMIC	20.411	Down-regulation
CK1_CK1_CK1-A_CSNK1A1_ST	Q9BXL7	CARD11	P48729	CSNK1A1	S618	P613L	613	Missense	distal	-5	no	21.130	20.934	EPSD	COSMIC	20.411	Down-regulation
CK1_CK1_CK1-A_CSNK1A1_ST	Q9BXL7	CARD11	P48729	CSNK1A1	S618	S622C	622	Missense	distal	4	no	21.130	21.011	EPSD	COSMIC	20.411	Down-regulation
CK1_CK1_CK1-A_CSNK1A1_ST	Q9BXL7	CARD11	P48729	CSNK1A1	S618	S625C	625	Missense	distal	7	no	21.130	21.283	EPSD	COSMIC	20.411	Up-regulation
CK1_CK1_CK1-A_CSNK1A1_ST	Q9BXL7	CARD11	P48729	CSNK1A1	S618	S618A	618	Missense	central	0	yes	21.130	0.000	EPSD	COSMIC;CCLE	20.411	Loss
CK1_CK1_CK1-A_CSNK1A1_ST	Q9BXL7	CARD11	P48729	CSNK1A1	S618	S619F	619	Missense	proximal	1	no	21.130	21.074	EPSD	COSMIC	20.411	Down-regulation
CK1_CK1_CK1-A_CSNK1A1_ST	Q9BXL7	CARD11	P48729	CSNK1A1	S618	H617Y	617	Missense	proximal	-1	no	21.130	21.391	EPSD	COSMIC	20.411	Up-regulation
CK1_CK1_CK1-A_CSNK1A1_ST	Q9BXL7	CARD11	P48729	CSNK1A1	S618	S615P	615	Missense	distal	-3	no	21.130	14.943	EPSD	COSMIC	20.411	Loss
CK1_CK1_CK1-A_CSNK1A1_ST	Q9BXL7	CARD11	P48729	CSNK1A1	S621	S618C	618	Missense	distal	-3	no	20.800	16.467	EPSD	COSMIC	20.411	Loss
CK1_CK1_CK1-A_CSNK1A1_ST	Q9BXL7	CARD11	P48729	CSNK1A1	S621	S618F	618	Missense	distal	-3	no	20.800	15.147	EPSD	COSMIC	20.411	Loss
CK1_CK1_CK1-A_CSNK1A1_ST	Q9BXL7	CARD11	P48729	CSNK1A1	S621	S615F	615	Missense	distal	-6	no	20.800	19.586	EPSD	COSMIC	20.411	Loss
CK1_CK1_CK1-A_CSNK1A1_ST	Q9BXL7	CARD11	P48729	CSNK1A1	S621	S622H	622	Missense	proximal	1	no	20.800	20.660	EPSD	COSMIC	20.411	Down-regulation
CK1_CK1_CK1-A_CSNK1A1_ST	Q9BXL7	CARD11	P48729	CSNK1A1	S621	S622F	622	Missense	proximal	1	no	20.800	20.743	EPSD	COSMIC	20.411	Down-regulation
CK1_CK1_CK1-A_CSNK1A1_ST	Q9BXL7	CARD11	P48729	CSNK1A1	S621	S622C	622	Missense	proximal	1	no	20.800	20.595	EPSD	COSMIC	20.411	Down-regulation
CK1_CK1_CK1-A_CSNK1A1_ST	Q9BXL7	CARD11	P48729	CSNK1A1	S621	S625C	625	Missense	distal	4	no	20.800	20.680	EPSD	COSMIC	20.411	Down-regulation
CK1_CK1_CK1-A_CSNK1A1_ST	Q9BXL7	CARD11	P48729	CSNK1A1	S621	S618A	618	Missense	distal	-3	no	20.800	16.343	EPSD	COSMIC;CCLE	20.411	Loss
CK1_CK1_CK1-A_CSNK1A1_ST	Q9BXL7	CARD11	P48729	CSNK1A1	S621	S619F	619	Missense	proximal	-2	no	20.800	18.933	EPSD	COSMIC	20.411	Loss
CK1_CK1_CK1-A_CSNK1A1_ST	Q9BXL7	CARD11	P48729	CSNK1A1	S621	E626Q	626	Missense	distal	5	no	20.800	20.708	EPSD	COSMIC	20.411	Down-regulation
CK1_CK1_CK1-A_CSNK1A1_ST	Q9BXL7	CARD11	P48729	CSNK1A1	S621	H617Y	617	Missense	distal	-4	no	20.800	22.321	EPSD	COSMIC	20.411	Up-regulation
CK1_CK1_CK1-A_CSNK1A1_ST	Q9BXL7	CARD11	P48729	CSNK1A1	S621	S615P	615	Missense	distal	-6	no	20.800	20.118	EPSD	COSMIC	20.411	Loss
CK1_CK1_CK1-A_CSNK1A1_ST	Q9BXL7	CARD11	P48729	CSNK1A1	S622	S618C	618	Missense	distal	-4	no	22.741	20.041	EPSD	COSMIC	20.411	Loss
CK1_CK1_CK1-A_CSNK1A1_ST	Q9BXL7	CARD11	P48729	CSNK1A1	S622	S618F	618	Missense	distal	-4	no	22.741	21.091	EPSD	COSMIC	20.411	Down-regulation
CK1_CK1_CK1-A_CSNK1A1_ST	Q9BXL7	CARD11	P48729	CSNK1A1	S622	S615F	615	Missense	distal	-7	no	22.741	22.323	EPSD	COSMIC	20.411	Down-regulation
CK1_CK1_CK1-A_CSNK1A1_ST	Q9BXL7	CARD11	P48729	CSNK1A1	S622	S622H	622	Missense	central	0	yes	22.741	0.000	EPSD	COSMIC	20.411	Loss
CK1_CK1_CK1-A_CSNK1A1_ST	Q9BXL7	CARD11	P48729	CSNK1A1	S622	S622F	622	Missense	central	0	yes	22.741	0.000	EPSD	COSMIC	20.411	Loss
CK1_CK1_CK1-A_CSNK1A1_ST	Q9BXL7	CARD11	P48729	CSNK1A1	S622	S622C	622	Missense	central	0	yes	22.741	0.000	EPSD	COSMIC	20.411	Loss
CK1_CK1_CK1-A_CSNK1A1_ST	Q9BXL7	CARD11	P48729	CSNK1A1	S622	S625C	625	Missense	distal	3	no	22.741	18.698	EPSD	COSMIC	20.411	Loss
CK1_CK1_CK1-A_CSNK1A1_ST	Q9BXL7	CARD11	P48729	CSNK1A1	S622	S618A	618	Missense	distal	-4	no	22.741	21.141	EPSD	COSMIC;CCLE	20.411	Down-regulation
CK1_CK1_CK1-A_CSNK1A1_ST	Q9BXL7	CARD11	P48729	CSNK1A1	S622	S619F	619	Missense	distal	-3	no	22.741	17.089	EPSD	COSMIC	20.411	Loss
CK1_CK1_CK1-A_CSNK1A1_ST	Q9BXL7	CARD11	P48729	CSNK1A1	S622	E626Q	626	Missense	distal	4	no	22.741	22.567	EPSD	COSMIC	20.411	Down-regulation
CK1_CK1_CK1-A_CSNK1A1_ST	Q9BXL7	CARD11	P48729	CSNK1A1	S622	H617Y	617	Missense	distal	-5	no	22.741	22.163	EPSD	COSMIC	20.411	Down-regulation
CK1_CK1_CK1-A_CSNK1A1_ST	Q9BXL7	CARD11	P48729	CSNK1A1	S622	S615P	615	Missense	distal	-7	no	22.741	22.075	EPSD	COSMIC	20.411	Down-regulation
CK1_CK1_CK1-A_CSNK1A1_ST	Q9BXL7	CARD11	P48729	CSNK1A1	S625	S618A	618	Missense	distal	-7	no	20.062	20.585	EPSD	COSMIC;CCLE	20.411	Gain
CK1_CK1_CK1-A_CSNK1A1_ST	Q9BXL7	CARD11	P48729	CSNK1A1	S879	S879L	879	Missense	central	0	yes	23.417	0.000	EPSD	COSMIC	20.411	Loss
CK1_CK1_CK1-A_CSNK1A1_ST	Q9BXL7	CARD11	P48729	CSNK1A1	S879	L878F	878	Missense	proximal	-1	no	23.417	22.990	EPSD	COSMIC	20.411	Down-regulation
CK1_CK1_CK1-A_CSNK1A1_ST	Q9BXL7	CARD11	P48729	CSNK1A1	S879	V885I	885	Missense	distal	6	no	23.417	23.875	EPSD	COSMIC	20.411	Up-regulation
CK1_CK1_CK1-A_CSNK1A1_ST	Q9BXL7	CARD11	P48729	CSNK1A1	S879	R884L	884	Missense	distal	5	no	23.417	23.320	EPSD	COSMIC	20.411	Down-regulation
CK1_CK1_CK1-A_CSNK1A1_ST	Q9BXL7	CARD11	P48729	CSNK1A1	S925	A931S	931	Missense	distal	6	no	20.163	20.521	EPSD	COSMIC	20.411	Gain
CK1_CK1_CK1-A_CSNK1A1_ST	Q9BXL7	CARD11	P48729	CSNK1A1	S925	R932W	932	Missense	distal	7	no	20.163	20.539	EPSD	COSMIC	20.411	Gain
CK1_CK1_CK1-A_CSNK1A1_ST	Q9BXL7	CARD11	P48729	CSNK1A1	S929	P926S	926	Missense	distal	-3	no	15.696	21.884	EPSD	COSMIC	20.411	Gain
CK1_CK1_CK1-A_CSNK1A1_ST	Q9BXL7	CARD11	P48729	CSNK1A1	S952	S959G	959	Missense	distal	7	no	21.761	21.782	EPSD	COSMIC	20.411	Up-regulation
CK1_CK1_CK1-A_CSNK1A1_ST	Q9BXL7	CARD11	P48729	CSNK1A1	S952	G955C	955	Missense	distal	3	no	21.761	17.270	EPSD	COSMIC	20.411	Loss
CK1_CK1_CK1-A_CSNK1A1_ST	Q9BXL7	CARD11	P48729	CSNK1A1	S952	P950L	950	Missense	proximal	-2	no	21.761	20.777	EPSD	COSMIC	20.411	Down-regulation
CK1_CK1_CK1-A_CSNK1A1_ST	Q9BXL7	CARD11	P48729	CSNK1A1	S952	G955D	955	Missense	distal	3	no	21.761	22.035	EPSD	COSMIC	20.411	Up-regulation
CK1_CK1_CK1-A_CSNK1A1_ST	Q9BXL7	CARD11	P48729	CSNK1A1	S952	E951K	951	Missense	proximal	-1	no	21.761	20.120	EPSD	COSMIC	20.411	Loss
CK1_CK1_CK1-A_CSNK1A1_ST	P18846	ATF1	P48729	CSNK1A1	S36	E39G	39	Missense	distal	3	no	21.391	21.257	EPSD;PhosphoSitePlus	COSMIC	20.411	Down-regulation
CK1_CK1_CK1-A_CSNK1A1_ST	P18846	ATF1	P48729	CSNK1A1	S36	V32I	32	Missense	distal	-4	no	21.391	21.976	EPSD;PhosphoSitePlus	COSMIC	20.411	Up-regulation
CK1_CK1_CK1-A_CSNK1A1_ST	P18846	ATF1	P48729	CSNK1A1	S36	E39K	39	Missense	distal	3	no	21.391	17.261	EPSD;PhosphoSitePlus	COSMIC	20.411	Loss
CK1_CK1_CK1-A_CSNK1A1_ST	P18846	ATF1	P48729	CSNK1A1	S41	E39G	39	Missense	proximal	-2	no	23.501	23.353	EPSD;PhosphoSitePlus	COSMIC	20.411	Down-regulation
CK1_CK1_CK1-A_CSNK1A1_ST	P18846	ATF1	P48729	CSNK1A1	S41	E39K	39	Missense	proximal	-2	no	23.501	22.188	EPSD;PhosphoSitePlus	COSMIC	20.411	Down-regulation
CK1_CK1_CK1-A_CSNK1A1_ST	P18846	ATF1	P48729	CSNK1A1	S189	R182G	182	Missense	distal	-7	no	19.823	20.474	EPSD	COSMIC;GDSC;CCLE	20.411	Gain
CK1_CK1_CK1-A_CSNK1A1_ST	Q9Y4G8	RAPGEF2	P48729	CSNK1A1	S935	T942K	942	Missense	distal	7	no	21.391	21.336	EPSD	COSMIC	20.411	Down-regulation
CK1_CK1_CK1-A_CSNK1A1_ST	Q9Y4G8	RAPGEF2	P48729	CSNK1A1	S935	R929P	929	Missense	distal	-6	no	21.391	21.238	EPSD	COSMIC	20.411	Down-regulation
CK1_CK1_CK1-A_CSNK1A1_ST	Q9Y4G8	RAPGEF2	P48729	CSNK1A1	S935	G932E	932	Missense	distal	-3	no	21.391	20.978	EPSD	COSMIC;GDSC	20.411	Down-regulation
CK1_CK1_CK1-A_CSNK1A1_ST	Q9Y4G8	RAPGEF2	P48729	CSNK1A1	S1095	H1099D	1099	Missense	distal	4	no	21.168	21.304	EPSD	COSMIC	20.411	Up-regulation
CK1_CK1_CK1-A_CSNK1A1_ST	Q9Y4G8	RAPGEF2	P48729	CSNK1A1	S1095	R1098C	1098	Missense	distal	3	no	21.168	19.568	EPSD	COSMIC	20.411	Loss
CK1_CK1_CK1-A_CSNK1A1_ST	Q9Y4G8	RAPGEF2	P48729	CSNK1A1	S1095	L1096F	1096	Missense	proximal	1	no	21.168	20.848	EPSD	COSMIC	20.411	Down-regulation
CK1_CK1_CK1-A_CSNK1A1_ST	Q9Y4G8	RAPGEF2	P48729	CSNK1A1	S1095	S1095F	1095	Missense	central	0	yes	21.168	0.000	EPSD	COSMIC	20.411	Loss
CK1_CK1_CK1-A_CSNK1A1_ST	Q9Y4G8	RAPGEF2	P48729	CSNK1A1	S1108	S1115Y	1115	Missense	distal	7	no	21.052	21.305	EPSD	COSMIC	20.411	Up-regulation
CK1_CK1_CK1-A_CSNK1A1_ST	Q9Y4G8	RAPGEF2	P48729	CSNK1A1	S1153	R1151L	1151	Missense	proximal	-2	no	22.514	20.751	EPSD	COSMIC	20.411	Down-regulation
CK1_CK1_CK1-A_CSNK1A1_ST	Q9Y4G8	RAPGEF2	P48729	CSNK1A1	S1153	S1159P	1159	Missense	distal	6	no	22.514	22.289	EPSD	COSMIC	20.411	Down-regulation
CK1_CK1_CK1-A_CSNK1A1_ST	Q9Y4G8	RAPGEF2	P48729	CSNK1A1	S1153	S1159Y	1159	Missense	distal	6	no	22.514	21.938	EPSD	COSMIC	20.411	Down-regulation
CK1_CK1_CK1-A_CSNK1A1_ST	Q9Y4G8	RAPGEF2	P48729	CSNK1A1	S1153	S1150C	1150	Missense	distal	-3	no	22.514	18.182	EPSD	COSMIC	20.411	Loss
CK1_CK1_CK1-A_CSNK1A1_ST	Q9Y4G8	RAPGEF2	P48729	CSNK1A1	S1156	R1151L	1151	Missense	distal	-5	no	21.524	21.766	EPSD	COSMIC	20.411	Up-regulation
CK1_CK1_CK1-A_CSNK1A1_ST	Q9Y4G8	RAPGEF2	P48729	CSNK1A1	S1156	S1159P	1159	Missense	distal	3	no	21.524	17.259	EPSD	COSMIC	20.411	Loss
CK1_CK1_CK1-A_CSNK1A1_ST	Q9Y4G8	RAPGEF2	P48729	CSNK1A1	S1156	S1159Y	1159	Missense	distal	3	no	21.524	18.719	EPSD	COSMIC	20.411	Loss
CK1_CK1_CK1-A_CSNK1A1_ST	Q9Y4G8	RAPGEF2	P48729	CSNK1A1	S1156	S1150C	1150	Missense	distal	-6	no	21.524	20.670	EPSD	COSMIC	20.411	Down-regulation
CK1_CK1_CK1-A_CSNK1A1_ST	Q9Y4G8	RAPGEF2	P48729	CSNK1A1	S1225	S1223C	1223	Missense	proximal	-2	no	20.882	19.564	EPSD	COSMIC	20.411	Loss
CK1_CK1_CK1-A_CSNK1A1_ST	Q9Y4G8	RAPGEF2	P48729	CSNK1A1	S1225	S1225R	1225	Missense	central	0	yes	20.882	0.000	EPSD	COSMIC	20.411	Loss
CK1_CK1_CK1-A_CSNK1A1_ST	Q9Y4G8	RAPGEF2	P48729	CSNK1A1	S1225	Q1231H	1231	Missense	distal	6	no	20.882	20.894	EPSD	COSMIC	20.411	Up-regulation
CK1_CK1_CK1-A_CSNK1A1_ST	Q9Y4G8	RAPGEF2	P48729	CSNK1A1	S1230	S1223C	1223	Missense	distal	-7	no	23.223	22.568	EPSD	COSMIC	20.411	Down-regulation
CK1_CK1_CK1-A_CSNK1A1_ST	Q9Y4G8	RAPGEF2	P48729	CSNK1A1	S1230	R1236H	1236	Missense	distal	6	no	23.223	23.152	EPSD	COSMIC	20.411	Down-regulation
CK1_CK1_CK1-A_CSNK1A1_ST	Q9Y4G8	RAPGEF2	P48729	CSNK1A1	S1230	S1225R	1225	Missense	distal	-5	no	23.223	22.352	EPSD	COSMIC	20.411	Down-regulation
CK1_CK1_CK1-A_CSNK1A1_ST	Q9Y4G8	RAPGEF2	P48729	CSNK1A1	S1230	Q1231H	1231	Missense	proximal	1	no	23.223	22.797	EPSD	COSMIC	20.411	Down-regulation
CK1_CK1_CK1-A_CSNK1A1_ST	Q9Y4G8	RAPGEF2	P48729	CSNK1A1	S1238	R1236H	1236	Missense	proximal	-2	no	21.897	20.276	EPSD	COSMIC	20.411	Loss
CK1_CK1_CK1-A_CSNK1A1_ST	Q9Y4G8	RAPGEF2	P48729	CSNK1A1	S1238	Q1231H	1231	Missense	distal	-7	no	21.897	20.726	EPSD	COSMIC	20.411	Down-regulation
CK1_CK1_CK1-A_CSNK1A1_ST	Q9Y4G8	RAPGEF2	P48729	CSNK1A1	S1244	R1246C	1246	Missense	proximal	2	no	24.769	24.391	EPSD;PhosphoSitePlus	COSMIC;GDSC;CCLE	20.411	Down-regulation
CK1_CK1_CK1-A_CSNK1A1_ST	Q9Y4G8	RAPGEF2	P48729	CSNK1A1	S1248	R1246C	1246	Missense	proximal	-2	no	21.193	20.965	PhosphoSitePlus;EPSD	COSMIC;GDSC;CCLE	20.411	Down-regulation
CK1_CK1_CK1-A_CSNK1A1_ST	Q9Y4G8	RAPGEF2	P48729	CSNK1A1	S1251	R1246C	1246	Missense	distal	-5	no	25.680	25.247	EPSD	COSMIC;GDSC;CCLE	20.411	Down-regulation
CK1_CK1_CK1-A_CSNK1A1_ST	Q9Y4G8	RAPGEF2	P48729	CSNK1A1	S1251	D1258N	1258	Missense	distal	7	no	25.680	25.763	EPSD	COSMIC	20.411	Up-regulation
CK1_CK1_CK1-A_CSNK1A1_ST	Q9Y4G8	RAPGEF2	P48729	CSNK1A1	S1254	D1258N	1258	Missense	distal	4	no	22.407	22.294	EPSD	COSMIC	20.411	Down-regulation
CK1_CK1_CK1-A_CSNK1A1_ST	Q9Y4G8	RAPGEF2	P48729	CSNK1A1	S1316	E1318Q	1318	Missense	proximal	2	no	27.746	27.480	EPSD	COSMIC	20.411	Down-regulation
CK1_CK1_CK1-A_CSNK1A1_ST	Q9Y4G8	RAPGEF2	P48729	CSNK1A1	S1322	E1318Q	1318	Missense	distal	-4	no	21.479	21.102	EPSD	COSMIC	20.411	Down-regulation
CK1_CK1_CK1-A_CSNK1A1_ST	Q9Y4G8	RAPGEF2	P48729	CSNK1A1	S1325	E1318Q	1318	Missense	distal	-7	no	23.302	22.845	EPSD	COSMIC	20.411	Down-regulation
CK1_CK1_CK1-A_CSNK1A1_ST	Q9Y4G8	RAPGEF2	P48729	CSNK1A1	S1325	G1331R	1331	Missense	distal	6	no	23.302	23.091	EPSD	COSMIC	20.411	Down-regulation
CK1_CK1_CK1-A_CSNK1A1_ST	Q9Y4G8	RAPGEF2	P48729	CSNK1A1	S1328	G1334R	1334	Missense	distal	6	no	20.464	20.252	EPSD	COSMIC	20.411	Loss
CK1_CK1_CK1-A_CSNK1A1_ST	Q9Y4G8	RAPGEF2	P48729	CSNK1A1	S1328	G1331R	1331	Missense	distal	3	no	20.464	17.573	EPSD	COSMIC	20.411	Loss
CK1_CK1_CK1-A_CSNK1A1_ST	Q9Y4G8	RAPGEF2	P48729	CSNK1A1	S1337	G1342C	1342	Missense	distal	5	no	22.652	22.664	EPSD	COSMIC	20.411	Up-regulation
CK1_CK1_CK1-A_CSNK1A1_ST	Q9Y4G8	RAPGEF2	P48729	CSNK1A1	S1337	G1334R	1334	Missense	distal	-3	no	22.652	20.117	EPSD	COSMIC	20.411	Loss
CK1_CK1_CK1-A_CSNK1A1_ST	Q9Y4G8	RAPGEF2	P48729	CSNK1A1	S1337	G1331R	1331	Missense	distal	-6	no	22.652	21.983	EPSD	COSMIC	20.411	Down-regulation
CK1_CK1_CK1-A_CSNK1A1_ST	Q9Y4G8	RAPGEF2	P48729	CSNK1A1	S1337	D1340Y	1340	Missense	distal	3	no	22.652	19.125	EPSD	COSMIC	20.411	Loss
CK1_CK1_CK1-A_CSNK1A1_ST	P04637	TP53	P48729	CSNK1A1	S6	E11Q	11	Missense	distal	5	no	22.651	22.559	EPSD	COSMIC;GDSC;CCLE	20.411	Down-regulation
CK1_CK1_CK1-A_CSNK1A1_ST	P04637	TP53	P48729	CSNK1A1	S6	P13S	13	Missense	distal	7	no	22.651	22.463	EPSD	COSMIC	20.411	Down-regulation
CK1_CK1_CK1-A_CSNK1A1_ST	P04637	TP53	P48729	CSNK1A1	S6	V10I	10	Missense	distal	4	no	22.651	22.767	EPSD	COSMIC	20.411	Up-regulation
CK1_CK1_CK1-A_CSNK1A1_ST	P04637	TP53	P48729	CSNK1A1	S6	P8L	8	Missense	proximal	2	no	22.651	22.681	EPSD	COSMIC	20.411	Up-regulation
CK1_CK1_CK1-A_CSNK1A1_ST	P04637	TP53	P48729	CSNK1A1	S6	P8S	8	Missense	proximal	2	no	22.651	23.666	EPSD	COSMIC	20.411	Up-regulation
CK1_CK1_CK1-A_CSNK1A1_ST	P04637	TP53	P48729	CSNK1A1	S6	P13L	13	Missense	distal	7	no	22.651	22.499	EPSD	COSMIC	20.411	Down-regulation
CK1_CK1_CK1-A_CSNK1A1_ST	P04637	TP53	P48729	CSNK1A1	S6	Q5H	5	Missense	proximal	-1	no	22.651	20.974	EPSD	COSMIC	20.411	Down-regulation
CK1_CK1_CK1-A_CSNK1A1_ST	P04637	TP53	P48729	CSNK1A1	S6	V10G	10	Missense	distal	4	no	22.651	22.775	EPSD	COSMIC	20.411	Up-regulation
CK1_CK1_CK1-A_CSNK1A1_ST	P04637	TP53	P48729	CSNK1A1	S6	E3G	3	Missense	distal	-3	no	22.651	23.064	EPSD	COSMIC	20.411	Up-regulation
CK1_CK1_CK1-A_CSNK1A1_ST	P04637	TP53	P48729	CSNK1A1	S6	D7H	7	Missense	proximal	1	no	22.651	22.337	EPSD	COSMIC	20.411	Down-regulation
CK1_CK1_CK1-A_CSNK1A1_ST	P04637	TP53	P48729	CSNK1A1	S6	S9G	9	Missense	distal	3	no	22.651	23.099	EPSD	COSMIC	20.411	Up-regulation
CK1_CK1_CK1-A_CSNK1A1_ST	P04637	TP53	P48729	CSNK1A1	S6	D7Y	7	Missense	proximal	1	no	22.651	22.408	EPSD	COSMIC	20.411	Down-regulation
CK1_CK1_CK1-A_CSNK1A1_ST	P04637	TP53	P48729	CSNK1A1	S9	E11Q	11	Missense	proximal	2	no	20.768	20.502	EPSD	COSMIC;GDSC;CCLE	20.411	Down-regulation
CK1_CK1_CK1-A_CSNK1A1_ST	P04637	TP53	P48729	CSNK1A1	S9	Q16L	16	Missense	distal	7	no	20.768	20.797	EPSD	COSMIC;GDSC;CCLE	20.411	Up-regulation
CK1_CK1_CK1-A_CSNK1A1_ST	P04637	TP53	P48729	CSNK1A1	S9	P13S	13	Missense	distal	4	no	20.768	20.805	EPSD	COSMIC	20.411	Up-regulation
CK1_CK1_CK1-A_CSNK1A1_ST	P04637	TP53	P48729	CSNK1A1	S9	V10I	10	Missense	proximal	1	no	20.768	20.955	EPSD	COSMIC	20.411	Up-regulation
CK1_CK1_CK1-A_CSNK1A1_ST	P04637	TP53	P48729	CSNK1A1	S9	P8L	8	Missense	proximal	-1	no	20.768	20.484	EPSD	COSMIC	20.411	Down-regulation
CK1_CK1_CK1-A_CSNK1A1_ST	P04637	TP53	P48729	CSNK1A1	S9	P8S	8	Missense	proximal	-1	no	20.768	20.760	EPSD	COSMIC	20.411	Down-regulation
CK1_CK1_CK1-A_CSNK1A1_ST	P04637	TP53	P48729	CSNK1A1	S9	P13L	13	Missense	distal	4	no	20.768	20.835	EPSD	COSMIC	20.411	Up-regulation
CK1_CK1_CK1-A_CSNK1A1_ST	P04637	TP53	P48729	CSNK1A1	S9	Q5H	5	Missense	distal	-4	no	20.768	16.513	EPSD	COSMIC	20.411	Loss
CK1_CK1_CK1-A_CSNK1A1_ST	P04637	TP53	P48729	CSNK1A1	S9	V10G	10	Missense	proximal	1	no	20.768	21.002	EPSD	COSMIC	20.411	Up-regulation
CK1_CK1_CK1-A_CSNK1A1_ST	P04637	TP53	P48729	CSNK1A1	S9	E3G	3	Missense	distal	-6	no	20.768	21.579	EPSD	COSMIC	20.411	Up-regulation
CK1_CK1_CK1-A_CSNK1A1_ST	P04637	TP53	P48729	CSNK1A1	S9	D7H	7	Missense	proximal	-2	no	20.768	18.174	EPSD	COSMIC	20.411	Loss
CK1_CK1_CK1-A_CSNK1A1_ST	P04637	TP53	P48729	CSNK1A1	S9	S9G	9	Missense	central	0	yes	20.768	0.000	EPSD	COSMIC	20.411	Loss
CK1_CK1_CK1-A_CSNK1A1_ST	P04637	TP53	P48729	CSNK1A1	S9	S15I	15	Missense	distal	6	no	20.768	20.765	EPSD	COSMIC	20.411	Down-regulation
CK1_CK1_CK1-A_CSNK1A1_ST	P04637	TP53	P48729	CSNK1A1	S9	D7Y	7	Missense	proximal	-2	no	20.768	18.843	EPSD	COSMIC	20.411	Loss
CK1_CK1_CK1-A_CSNK1A1_ST	P04637	TP53	P48729	CSNK1A1	S46	M40I	40	Missense	distal	-6	no	20.672	19.804	EPSD	COSMIC	20.411	Loss
CK1_CK1_CK1-A_CSNK1A1_ST	P04637	TP53	P48729	CSNK1A1	S46	W53C	53	Missense	distal	7	no	20.672	20.341	EPSD	COSMIC	20.411	Loss
CK1_CK1_CK1-A_CSNK1A1_ST	P04637	TP53	P48729	CSNK1A1	S46	W53G	53	Missense	distal	7	no	20.672	20.210	EPSD	COSMIC	20.411	Loss
CK1_CK1_CK1-A_CSNK1A1_ST	P04637	TP53	P48729	CSNK1A1	S46	S46F	46	Missense	central	0	yes	20.672	0.000	EPSD	COSMIC	20.411	Loss
CK1_CK1_CK1-A_CSNK1A1_ST	P04637	TP53	P48729	CSNK1A1	S46	D49Y	49	Missense	distal	3	no	20.672	17.145	EPSD	COSMIC	20.411	Loss
CK1_CK1_CK1-A_CSNK1A1_ST	P04637	TP53	P48729	CSNK1A1	S46	P47L	47	Missense	proximal	1	no	20.672	20.782	EPSD	COSMIC	20.411	Up-regulation
CK1_CK1_CK1-A_CSNK1A1_ST	P04637	TP53	P48729	CSNK1A1	S46	D49H	49	Missense	distal	3	no	20.672	16.124	EPSD	COSMIC;GDSC;CCLE	20.411	Loss
CK1_CK1_CK1-A_CSNK1A1_ST	P04637	TP53	P48729	CSNK1A1	S46	P47S	47	Missense	proximal	1	no	20.672	20.519	EPSD	COSMIC	20.411	Down-regulation
CK1_CK1_CK1-A_CSNK1A1_ST	P04637	TP53	P48729	CSNK1A1	S46	D41N	41	Missense	distal	-5	no	20.672	20.422	EPSD	COSMIC	20.411	Down-regulation
CK1_CK1_CK1-A_CSNK1A1_ST	P04637	TP53	P48729	CSNK1A1	S46	D48H	48	Missense	proximal	2	no	20.672	19.198	EPSD	COSMIC	20.411	Loss
CK1_CK1_CK1-A_CSNK1A1_ST	P04637	TP53	P48729	CSNK1A1	S46	D49N	49	Missense	distal	3	no	20.672	17.472	EPSD	COSMIC	20.411	Loss
CK1_CK1_CK1-A_CSNK1A1_ST	P04637	TP53	P48729	CSNK1A1	S46	M44I	44	Missense	proximal	-2	no	20.672	19.763	EPSD	COSMIC	20.411	Loss
CK1_CK1_CK1-A_CSNK1A1_ST	P04637	TP53	P48729	CSNK1A1	S46	Q52H	52	Missense	distal	6	no	20.672	20.684	EPSD	COSMIC	20.411	Up-regulation
CK1_CK1_CK1-A_CSNK1A1_ST	P04637	TP53	P48729	CSNK1A1	S46	D49V	49	Missense	distal	3	no	20.672	17.365	EPSD	COSMIC	20.411	Loss
CK1_CK1_CK1-A_CSNK1A1_ST	P04637	TP53	P48729	CSNK1A1	S46	A39V	39	Missense	distal	-7	no	20.672	18.436	EPSD	COSMIC	20.411	Loss
CK1_CK1_CK1-A_CSNK1A1_ST	P04637	TP53	P48729	CSNK1A1	S46	A39S	39	Missense	distal	-7	no	20.672	20.149	EPSD	COSMIC	20.411	Loss
CK1_CK1_CK1-A_CSNK1A1_ST	P04637	TP53	P48729	CSNK1A1	S46	D42Y	42	Missense	distal	-4	no	20.672	17.125	EPSD	COSMIC	20.411	Loss
CK1_CK1_CK1-A_CSNK1A1_ST	P04637	TP53	P48729	CSNK1A1	S46	M44R	44	Missense	proximal	-2	no	20.672	20.852	EPSD	COSMIC	20.411	Up-regulation
CK1_CK1_CK1-A_CSNK1A1_ST	P04637	TP53	P48729	CSNK1A1	S46	S46P	46	Missense	central	0	yes	20.672	0.000	EPSD	COSMIC	20.411	Loss
CK1_CK1_CK1-A_CSNK1A1_ST	P04637	TP53	P48729	CSNK1A1	S46	M44V	44	Missense	proximal	-2	no	20.672	19.585	EPSD	COSMIC	20.411	Loss
CK1_CK1_CK1-A_CSNK1A1_ST	P04637	TP53	P48729	CSNK1A1	S46	L45P	45	Missense	proximal	-1	no	20.672	20.955	EPSD	COSMIC	20.411	Up-regulation
CK1_CK1_CK1-A_CSNK1A1_ST	P04637	TP53	P48729	CSNK1A1	S46	M44T	44	Missense	proximal	-2	no	20.672	20.809	EPSD	COSMIC	20.411	Up-regulation
CK1_CK1_CK1-A_CSNK1A1_ST	P04637	TP53	P48729	CSNK1A1	S46	A39T	39	Missense	distal	-7	no	20.672	19.700	EPSD	COSMIC	20.411	Loss
CK1_CK1_CK1-A_CSNK1A1_ST	P04637	TP53	P48729	CSNK1A1	S46	L43F	43	Missense	distal	-3	no	20.672	21.613	EPSD	COSMIC	20.411	Up-regulation
CK1_CK1_CK1-A_CSNK1A1_ST	P04637	TP53	P48729	CSNK1A1	S46	D41H	41	Missense	distal	-5	no	20.672	19.224	EPSD	COSMIC	20.411	Loss
CK1_CK1_CK1-A_CSNK1A1_ST	P04637	TP53	P48729	CSNK1A1	S46	D49E	49	Missense	distal	3	no	20.672	20.532	EPSD	COSMIC	20.411	Down-regulation
CK1_CK1_CK1-A_CSNK1A1_ST	P04637	TP53	P48729	CSNK1A1	S46	D49G	49	Missense	distal	3	no	20.672	20.398	EPSD	COSMIC	20.411	Loss
CK1_CK1_CK1-A_CSNK1A1_ST	P04637	TP53	P48729	CSNK1A1	S46	D48A	48	Missense	proximal	2	no	20.672	19.700	EPSD	COSMIC	20.411	Loss
CK1_CK1_CK1-A_CSNK1A1_ST	P04637	TP53	P48729	CSNK1A1	S46	D48Y	48	Missense	proximal	2	no	20.672	19.205	EPSD	COSMIC	20.411	Loss
CK1_CK1_CK1-A_CSNK1A1_ST	P04637	TP53	P48729	CSNK1A1	S46	D48E	48	Missense	proximal	2	no	20.672	20.480	EPSD	COSMIC	20.411	Down-regulation
CK1_CK1_CK1-A_CSNK1A1_ST	P04637	TP53	P48729	CSNK1A1	S46	D49I	49	Missense	distal	3	no	20.672	18.694	EPSD	COSMIC	20.411	Loss
CK1_CK1_CK1-A_CSNK1A1_ST	P04637	TP53	P48729	CSNK1A1	S46	D41E	41	Missense	distal	-5	no	20.672	19.952	EPSD	COSMIC	20.411	Loss
CK1_CK1_CK1-A_CSNK1A1_ST	P17931	LGALS3	P48729	CSNK1A1	S12	P17Q	17	Missense	distal	5	no	22.212	21.839	EPSD;PhosphoSitePlus	COSMIC	20.411	Down-regulation
CK1_CK1_CK1-A_CSNK1A1_ST	P17931	LGALS3	P48729	CSNK1A1	S188	W181R	181	Missense	distal	-7	no	18.932	20.968	EPSD	COSMIC	20.411	Gain
CK1_CK1_CK1-A_CSNK1A1_ST	Q13009	TIAM1	P48729	CSNK1A1	S63	A69T	69	Missense	distal	6	no	23.913	24.167	EPSD	COSMIC	20.411	Up-regulation
CK1_CK1_CK1-A_CSNK1A1_ST	Q13009	TIAM1	P48729	CSNK1A1	S63	S58F	58	Missense	distal	-5	no	23.913	22.013	EPSD	COSMIC	20.411	Down-regulation
CK1_CK1_CK1-A_CSNK1A1_ST	Q13009	TIAM1	P48729	CSNK1A1	S219	M214I	214	Missense	distal	-5	no	20.495	19.737	EPSD	COSMIC	20.411	Loss
CK1_CK1_CK1-A_CSNK1A1_ST	Q13009	TIAM1	P48729	CSNK1A1	S219	R217L	217	Missense	proximal	-2	no	20.495	18.731	EPSD	COSMIC	20.411	Loss
CK1_CK1_CK1-A_CSNK1A1_ST	Q13009	TIAM1	P48729	CSNK1A1	S219	T216M	216	Missense	distal	-3	no	20.495	22.003	EPSD	COSMIC;GDSC	20.411	Up-regulation
CK1_CK1_CK1-A_CSNK1A1_ST	Q13009	TIAM1	P48729	CSNK1A1	S334	S334R	334	Missense	central	0	yes	20.464	0.000	EPSD	COSMIC	20.411	Loss
CK1_CK1_CK1-A_CSNK1A1_ST	Q13009	TIAM1	P48729	CSNK1A1	S334	I336V	336	Missense	proximal	2	no	20.464	19.990	EPSD	COSMIC	20.411	Loss
CK1_CK1_CK1-A_CSNK1A1_ST	Q13009	TIAM1	P48729	CSNK1A1	S334	A339T	339	Missense	distal	5	no	20.464	20.357	EPSD	COSMIC	20.411	Loss
CK1_CK1_CK1-A_CSNK1A1_ST	Q13009	TIAM1	P48729	CSNK1A1	S334	T341I	341	Missense	distal	7	no	20.464	20.314	EPSD	COSMIC	20.411	Loss
CK1_CK1_CK1-A_CSNK1A1_ST	Q13009	TIAM1	P48729	CSNK1A1	S356	P359S	359	Missense	distal	3	no	16.352	20.618	EPSD	COSMIC	20.411	Gain
CK1_CK1_CK1-A_CSNK1A1_ST	Q13009	TIAM1	P48729	CSNK1A1	S372	S374F	374	Missense	proximal	2	no	20.561	19.539	EPSD	COSMIC	20.411	Loss
CK1_CK1_CK1-A_CSNK1A1_ST	Q13009	TIAM1	P48729	CSNK1A1	S372	G376E	376	Missense	distal	4	no	20.561	20.637	EPSD	COSMIC	20.411	Up-regulation
CK1_CK1_CK1-A_CSNK1A1_ST	Q13009	TIAM1	P48729	CSNK1A1	S372	S372I	372	Missense	central	0	yes	20.561	0.000	EPSD	COSMIC	20.411	Loss
CK1_CK1_CK1-A_CSNK1A1_ST	Q13009	TIAM1	P48729	CSNK1A1	S372	A379V	379	Missense	distal	7	no	20.561	20.680	EPSD	COSMIC	20.411	Up-regulation
CK1_CK1_CK1-A_CSNK1A1_ST	Q13009	TIAM1	P48729	CSNK1A1	S373	S374F	374	Missense	proximal	1	no	23.499	23.442	EPSD	COSMIC	20.411	Down-regulation
CK1_CK1_CK1-A_CSNK1A1_ST	Q13009	TIAM1	P48729	CSNK1A1	S373	G376E	376	Missense	distal	3	no	23.499	23.633	EPSD	COSMIC	20.411	Up-regulation
CK1_CK1_CK1-A_CSNK1A1_ST	Q13009	TIAM1	P48729	CSNK1A1	S373	S372I	372	Missense	proximal	-1	no	23.499	24.256	EPSD	COSMIC	20.411	Up-regulation
CK1_CK1_CK1-A_CSNK1A1_ST	Q13009	TIAM1	P48729	CSNK1A1	S373	A379V	379	Missense	distal	6	no	23.499	23.396	EPSD	COSMIC	20.411	Down-regulation
CK1_CK1_CK1-A_CSNK1A1_ST	Q13009	TIAM1	P48729	CSNK1A1	S374	S374F	374	Missense	central	0	yes	23.810	0.000	EPSD	COSMIC	20.411	Loss
CK1_CK1_CK1-A_CSNK1A1_ST	Q13009	TIAM1	P48729	CSNK1A1	S374	G376E	376	Missense	proximal	2	no	23.810	23.415	EPSD	COSMIC	20.411	Down-regulation
CK1_CK1_CK1-A_CSNK1A1_ST	Q13009	TIAM1	P48729	CSNK1A1	S374	Q381H	381	Missense	distal	7	no	23.810	24.037	EPSD	COSMIC;GDSC;CCLE	20.411	Up-regulation
CK1_CK1_CK1-A_CSNK1A1_ST	Q13009	TIAM1	P48729	CSNK1A1	S374	S372I	372	Missense	proximal	-2	no	23.810	21.631	EPSD	COSMIC	20.411	Down-regulation
CK1_CK1_CK1-A_CSNK1A1_ST	Q13009	TIAM1	P48729	CSNK1A1	S374	A379V	379	Missense	distal	5	no	23.810	23.843	EPSD	COSMIC	20.411	Up-regulation
CK1_CK1_CK1-A_CSNK1A1_ST	Q13009	TIAM1	P48729	CSNK1A1	S483	S479R	479	Missense	distal	-4	no	25.529	23.496	EPSD	COSMIC	20.411	Down-regulation
CK1_CK1_CK1-A_CSNK1A1_ST	Q13009	TIAM1	P48729	CSNK1A1	S483	S483A	483	Missense	central	0	yes	25.529	0.000	EPSD	COSMIC;CCLE	20.411	Loss
CK1_CK1_CK1-A_CSNK1A1_ST	Q13009	TIAM1	P48729	CSNK1A1	S483	S483F	483	Missense	central	0	yes	25.529	0.000	EPSD	COSMIC	20.411	Loss
CK1_CK1_CK1-A_CSNK1A1_ST	Q13009	TIAM1	P48729	CSNK1A1	S483	R482K	482	Missense	proximal	-1	no	25.529	25.409	EPSD	COSMIC	20.411	Down-regulation
CK1_CK1_CK1-A_CSNK1A1_ST	Q13009	TIAM1	P48729	CSNK1A1	S483	R482W	482	Missense	proximal	-1	no	25.529	24.491	EPSD	COSMIC	20.411	Down-regulation
CK1_CK1_CK1-A_CSNK1A1_ST	Q13009	TIAM1	P48729	CSNK1A1	S483	R482Q	482	Missense	proximal	-1	no	25.529	26.525	EPSD	COSMIC	20.411	Up-regulation
CK1_CK1_CK1-A_CSNK1A1_ST	Q13009	TIAM1	P48729	CSNK1A1	S489	P491S	491	Missense	proximal	2	no	19.731	20.746	EPSD	COSMIC;GDSC;CCLE	20.411	Gain
CK1_CK1_CK1-A_CSNK1A1_ST	Q13009	TIAM1	P48729	CSNK1A1	S989	E982K	982	Missense	distal	-7	no	20.497	20.735	EPSD	COSMIC;GDSC;CCLE	20.411	Up-regulation
CK1_CK1_CK1-A_CSNK1A1_ST	Q13009	TIAM1	P48729	CSNK1A1	S989	E982G	982	Missense	distal	-7	no	20.497	21.004	EPSD	COSMIC	20.411	Up-regulation
CK1_CK1_CK1-A_CSNK1A1_ST	Q13009	TIAM1	P48729	CSNK1A1	S989	T992A	992	Missense	distal	3	no	20.497	20.701	EPSD	COSMIC	20.411	Up-regulation
CK1_CK1_CK1-A_CSNK1A1_ST	Q13009	TIAM1	P48729	CSNK1A1	S989	S995N	995	Missense	distal	6	no	20.497	20.280	EPSD	COSMIC	20.411	Loss
CK1_CK1_CK1-A_CSNK1A1_ST	Q13009	TIAM1	P48729	CSNK1A1	T992	T992A	992	Missense	central	0	yes	21.646	0.000	EPSD	COSMIC	20.411	Loss
CK1_CK1_CK1-A_CSNK1A1_ST	Q13009	TIAM1	P48729	CSNK1A1	T992	T999R	999	Missense	distal	7	no	21.646	21.693	EPSD	COSMIC	20.411	Up-regulation
CK1_CK1_CK1-A_CSNK1A1_ST	Q13009	TIAM1	P48729	CSNK1A1	T992	S995N	995	Missense	distal	3	no	21.646	19.168	EPSD	COSMIC	20.411	Loss
CK1_CK1_CK1-A_CSNK1A1_ST	Q13009	TIAM1	P48729	CSNK1A1	S1020	P1014H	1014	Missense	distal	-6	no	23.833	23.409	EPSD	COSMIC	20.411	Down-regulation
CK1_CK1_CK1-A_CSNK1A1_ST	Q13009	TIAM1	P48729	CSNK1A1	S1020	Q1022E	1022	Missense	proximal	2	no	23.833	24.099	EPSD	COSMIC	20.411	Up-regulation
CK1_CK1_CK1-A_CSNK1A1_ST	Q13009	TIAM1	P48729	CSNK1A1	S1020	S1024Y	1024	Missense	distal	4	no	23.833	23.691	EPSD	COSMIC	20.411	Down-regulation
CK1_CK1_CK1-A_CSNK1A1_ST	Q13009	TIAM1	P48729	CSNK1A1	S1020	D1023V	1023	Missense	distal	3	no	23.833	20.527	EPSD	COSMIC	20.411	Down-regulation
CK1_CK1_CK1-A_CSNK1A1_ST	Q13009	TIAM1	P48729	CSNK1A1	S1020	G1026W	1026	Missense	distal	6	no	23.833	23.128	EPSD	COSMIC	20.411	Down-regulation
CK1_CK1_CK1-A_CSNK1A1_ST	Q13009	TIAM1	P48729	CSNK1A1	S1020	P1014S	1014	Missense	distal	-6	no	23.833	24.515	EPSD	COSMIC;CCLE	20.411	Up-regulation
CK1_CK1_CK1-A_CSNK1A1_ST	Q13009	TIAM1	P48729	CSNK1A1	S1465	A1464E	1464	Missense	proximal	-1	no	19.881	21.068	EPSD	COSMIC	20.411	Gain
CK1_CK1_CK1-A_CSNK1A1_ST	Q13009	TIAM1	P48729	CSNK1A1	S1466	K1469R	1469	Missense	distal	3	no	19.546	20.650	EPSD	COSMIC	20.411	Gain
CK1_CK1_CK1-A_CSNK1A1_ST	Q13009	TIAM1	P48729	CSNK1A1	S1466	A1464E	1464	Missense	proximal	-2	no	19.546	20.503	EPSD	COSMIC	20.411	Gain
CK1_CK1_CK1-A_CSNK1A1_ST	Q12968	NFATC3	P48729	CSNK1A1	S98	G102D	102	Missense	distal	4	no	21.252	21.256	EPSD	COSMIC	20.411	Up-regulation
CK1_CK1_CK1-A_CSNK1A1_ST	Q12968	NFATC3	P48729	CSNK1A1	S98	E94A	94	Missense	distal	-4	no	21.252	19.093	EPSD	COSMIC	20.411	Loss
CK1_CK1_CK1-A_CSNK1A1_ST	Q12968	NFATC3	P48729	CSNK1A1	S163	P166S	166	Missense	distal	3	no	18.668	22.933	EPSD	COSMIC	20.411	Gain
CK1_CK1_CK1-A_CSNK1A1_ST	Q12968	NFATC3	P48729	CSNK1A1	S168	P166S	166	Missense	proximal	-2	no	22.546	24.416	EPSD	COSMIC	20.411	Up-regulation
CK1_CK1_CK1-A_CSNK1A1_ST	Q12968	NFATC3	P48729	CSNK1A1	S168	S161Y	161	Missense	distal	-7	no	22.546	21.078	EPSD	COSMIC	20.411	Down-regulation
CK1_CK1_CK1-A_CSNK1A1_ST	Q12968	NFATC3	P48729	CSNK1A1	S169	P166S	166	Missense	distal	-3	no	18.602	24.789	EPSD	COSMIC	20.411	Gain
CK1_CK1_CK1-A_CSNK1A1_ST	Q12968	NFATC3	P48729	CSNK1A1	S269	S269Y	269	Missense	central	0	yes	20.697	0.000	EPSD	COSMIC	20.411	Loss
CK1_CK1_CK1-A_CSNK1A1_ST	Q12968	NFATC3	P48729	CSNK1A1	S269	T268I	268	Missense	proximal	-1	no	20.697	21.851	EPSD	COSMIC	20.411	Up-regulation
CK1_CK1_CK1-A_CSNK1A1_ST	Q12968	NFATC3	P48729	CSNK1A1	S300	P297S	297	Missense	distal	-3	no	19.121	25.309	EPSD	COSMIC	20.411	Gain
CK1_CK1_CK1-A_CSNK1A1_ST	Q12968	NFATC3	P48729	CSNK1A1	S731	P729S	729	Missense	proximal	-2	no	18.540	20.411	EPSD	COSMIC	20.411	Gain
CK1_CK1_CK1-A_CSNK1A1_ST	Q12968	NFATC3	P48729	CSNK1A1	S742	D738E	738	Missense	distal	-4	no	21.943	21.507	EPSD	COSMIC	20.411	Down-regulation
CK1_CK1_CK1-A_CSNK1A1_ST	Q12968	NFATC3	P48729	CSNK1A1	S742	S739R	739	Missense	distal	-3	no	21.943	17.717	EPSD	COSMIC;GDSC;CCLE	20.411	Loss
CK1_CK1_CK1-A_CSNK1A1_ST	O60716	CTNND1	P48729	CSNK1A1	T134	R135C	135	Missense	proximal	1	no	21.402	21.252	EPSD	COSMIC	20.411	Down-regulation
CK1_CK1_CK1-A_CSNK1A1_ST	O60716	CTNND1	P48729	CSNK1A1	T134	T134I	134	Missense	central	0	yes	21.402	0.000	EPSD	COSMIC	20.411	Loss
CK1_CK1_CK1-A_CSNK1A1_ST	O60716	CTNND1	P48729	CSNK1A1	T134	R135W	135	Missense	proximal	1	no	21.402	21.063	EPSD	COSMIC	20.411	Down-regulation
CK1_CK1_CK1-A_CSNK1A1_ST	O60716	CTNND1	P48729	CSNK1A1	T134	R135P	135	Missense	proximal	1	no	21.402	21.608	EPSD	COSMIC	20.411	Up-regulation
CK1_CK1_CK1-A_CSNK1A1_ST	O60716	CTNND1	P48729	CSNK1A1	S169	S168G	168	Missense	proximal	-1	no	20.796	21.495	EPSD	COSMIC	20.411	Up-regulation
CK1_CK1_CK1-A_CSNK1A1_ST	O60716	CTNND1	P48729	CSNK1A1	S169	A167V	167	Missense	proximal	-2	no	20.796	19.399	EPSD	COSMIC	20.411	Loss
CK1_CK1_CK1-A_CSNK1A1_ST	O60716	CTNND1	P48729	CSNK1A1	S171	S168G	168	Missense	distal	-3	no	21.622	19.931	EPSD	COSMIC	20.411	Loss
CK1_CK1_CK1-A_CSNK1A1_ST	O60716	CTNND1	P48729	CSNK1A1	S171	A167V	167	Missense	distal	-4	no	21.622	20.438	EPSD	COSMIC	20.411	Down-regulation
CK1_CK1_CK1-A_CSNK1A1_ST	O60716	CTNND1	P48729	CSNK1A1	S232	T235I	235	Missense	distal	3	no	19.733	20.911	EPSD	COSMIC	20.411	Gain
CK1_CK1_CK1-A_CSNK1A1_ST	O60716	CTNND1	P48729	CSNK1A1	S252	P251H	251	Missense	proximal	-1	no	20.799	19.645	EPSD	COSMIC	20.411	Loss
CK1_CK1_CK1-A_CSNK1A1_ST	O60716	CTNND1	P48729	CSNK1A1	S252	G258R	258	Missense	distal	6	no	20.799	20.588	EPSD	COSMIC	20.411	Down-regulation
CK1_CK1_CK1-A_CSNK1A1_ST	O60716	CTNND1	P48729	CSNK1A1	S252	R253I	253	Missense	proximal	1	no	20.799	21.026	EPSD	COSMIC	20.411	Up-regulation
CK1_CK1_CK1-A_CSNK1A1_ST	O60716	CTNND1	P48729	CSNK1A1	S252	M245L	245	Missense	distal	-7	no	20.799	20.220	EPSD	COSMIC	20.411	Loss
CK1_CK1_CK1-A_CSNK1A1_ST	O60716	CTNND1	P48729	CSNK1A1	S288	R287H	287	Missense	proximal	-1	no	22.680	21.999	EPSD	COSMIC	20.411	Down-regulation
CK1_CK1_CK1-A_CSNK1A1_ST	O60716	CTNND1	P48729	CSNK1A1	S288	M289T	289	Missense	proximal	1	no	22.680	22.746	EPSD	COSMIC	20.411	Up-regulation
CK1_CK1_CK1-A_CSNK1A1_ST	O60716	CTNND1	P48729	CSNK1A1	S312	R316W	316	Missense	distal	4	no	22.413	22.137	EPSD	COSMIC	20.411	Down-regulation
CK1_CK1_CK1-A_CSNK1A1_ST	O60716	CTNND1	P48729	CSNK1A1	S312	R306H	306	Missense	distal	-6	no	22.413	21.835	EPSD	COSMIC	20.411	Down-regulation
CK1_CK1_CK1-A_CSNK1A1_ST	O60716	CTNND1	P48729	CSNK1A1	S312	S312Y	312	Missense	central	0	yes	22.413	0.000	EPSD	COSMIC	20.411	Loss
CK1_CK1_CK1-A_CSNK1A1_ST	O60716	CTNND1	P48729	CSNK1A1	S312	R316L	316	Missense	distal	4	no	22.413	22.414	EPSD	COSMIC	20.411	Up-regulation
CK1_CK1_CK1-A_CSNK1A1_ST	O60716	CTNND1	P48729	CSNK1A1	S331	E328D	328	Missense	distal	-3	no	18.911	21.386	EPSD	COSMIC	20.411	Gain
CK1_CK1_CK1-A_CSNK1A1_ST	O60716	CTNND1	P48729	CSNK1A1	S349	S352N	352	Missense	distal	3	no	21.809	19.331	EPSD	COSMIC	20.411	Loss
CK1_CK1_CK1-A_CSNK1A1_ST	O60716	CTNND1	P48729	CSNK1A1	S349	S346N	346	Missense	distal	-3	no	21.809	16.901	EPSD	COSMIC	20.411	Loss
CK1_CK1_CK1-A_CSNK1A1_ST	O60716	CTNND1	P48729	CSNK1A1	S539	N536D	536	Missense	distal	-3	no	15.267	20.547	EPSD	COSMIC	20.411	Gain
CK1_CK1_CK1-A_CSNK1A1_ST	O60716	CTNND1	P48729	CSNK1A1	S847	G843D	843	Missense	distal	-4	no	20.084	20.913	EPSD	COSMIC	20.411	Gain
CK1_CK1_CK1-A_CSNK1A1_ST	O60716	CTNND1	P48729	CSNK1A1	S859	N855S	855	Missense	distal	-4	no	19.541	22.285	EPSD	COSMIC	20.411	Gain
CK1_CK1_CK1-A_CSNK1A1_ST	O60716	CTNND1	P48729	CSNK1A1	S861	H863D	863	Missense	proximal	2	no	19.814	21.288	EPSD	COSMIC	20.411	Gain
CK1_CK1_CK1-A_CSNK1A1_ST	O60716	CTNND1	P48729	CSNK1A1	S861	N855S	855	Missense	distal	-6	no	19.814	20.828	EPSD	COSMIC	20.411	Gain
CK1_CK1_CK1-A_CSNK1A1_ST	O60716	CTNND1	P48729	CSNK1A1	S864	H863D	863	Missense	proximal	-1	no	22.669	24.240	EPSD	COSMIC	20.411	Up-regulation
CK1_CK1_CK1-A_CSNK1A1_ST	O60716	CTNND1	P48729	CSNK1A1	S943	M936L	936	Missense	distal	-7	no	20.801	20.222	EPSD	COSMIC;GDSC	20.411	Loss
CK1_CK1_CK1-A_CSNK1A1_ST	Q6IE81	JADE1	P48729	CSNK1A1	S13	D14G	14	Missense	proximal	1	no	21.288	21.334	EPSD	COSMIC;GDSC	20.411	Up-regulation
CK1_CK1_CK1-A_CSNK1A1_ST	Q6IE81	JADE1	P48729	CSNK1A1	S18	D14G	14	Missense	distal	-4	no	22.261	21.432	PhosphoSitePlus;EPSD	COSMIC;GDSC	20.411	Down-regulation
CK1_CK1_CK1-A_CSNK1A1_ST	Q6IE81	JADE1	P48729	CSNK1A1	S547	S547P	547	Missense	central	0	yes	23.164	0.000	EPSD	COSMIC	20.411	Loss
CK1_CK1_CK1-A_CSNK1A1_ST	Q6IE81	JADE1	P48729	CSNK1A1	S547	S548P	548	Missense	proximal	1	no	23.164	23.316	EPSD	COSMIC;GDSC	20.411	Up-regulation
CK1_CK1_CK1-A_CSNK1A1_ST	Q6IE81	JADE1	P48729	CSNK1A1	S547	C546W	546	Missense	proximal	-1	no	23.164	22.841	EPSD	COSMIC	20.411	Down-regulation
CK1_CK1_CK1-A_CSNK1A1_ST	Q6IE81	JADE1	P48729	CSNK1A1	S547	G541D	541	Missense	distal	-6	no	23.164	23.289	EPSD	COSMIC	20.411	Up-regulation
CK1_CK1_CK1-A_CSNK1A1_ST	Q6IE81	JADE1	P48729	CSNK1A1	S547	V542L	542	Missense	distal	-5	no	23.164	24.294	EPSD	COSMIC	20.411	Up-regulation
CK1_CK1_CK1-A_CSNK1A1_ST	Q6IE81	JADE1	P48729	CSNK1A1	S548	L555P	555	Missense	distal	7	no	22.594	22.747	EPSD	COSMIC	20.411	Up-regulation
CK1_CK1_CK1-A_CSNK1A1_ST	Q6IE81	JADE1	P48729	CSNK1A1	S548	S547P	547	Missense	proximal	-1	no	22.594	22.603	EPSD	COSMIC	20.411	Up-regulation
CK1_CK1_CK1-A_CSNK1A1_ST	Q6IE81	JADE1	P48729	CSNK1A1	S548	S548P	548	Missense	central	0	yes	22.594	0.000	EPSD	COSMIC;GDSC	20.411	Loss
CK1_CK1_CK1-A_CSNK1A1_ST	Q6IE81	JADE1	P48729	CSNK1A1	S548	C546W	546	Missense	proximal	-2	no	22.594	23.369	EPSD	COSMIC	20.411	Up-regulation
CK1_CK1_CK1-A_CSNK1A1_ST	Q6IE81	JADE1	P48729	CSNK1A1	S548	G541D	541	Missense	distal	-7	no	22.594	21.802	EPSD	COSMIC	20.411	Down-regulation
CK1_CK1_CK1-A_CSNK1A1_ST	Q6IE81	JADE1	P48729	CSNK1A1	S548	V542L	542	Missense	distal	-6	no	22.594	22.867	EPSD	COSMIC	20.411	Up-regulation
CK1_CK1_CK1-A_CSNK1A1_ST	Q6IE81	JADE1	P48729	CSNK1A1	S549	L555P	555	Missense	distal	6	no	23.961	23.875	EPSD	COSMIC	20.411	Down-regulation
CK1_CK1_CK1-A_CSNK1A1_ST	Q6IE81	JADE1	P48729	CSNK1A1	S549	S547P	547	Missense	proximal	-2	no	23.961	22.091	EPSD	COSMIC	20.411	Down-regulation
CK1_CK1_CK1-A_CSNK1A1_ST	Q6IE81	JADE1	P48729	CSNK1A1	S549	S548P	548	Missense	proximal	-1	no	23.961	23.970	EPSD	COSMIC;GDSC	20.411	Up-regulation
CK1_CK1_CK1-A_CSNK1A1_ST	Q6IE81	JADE1	P48729	CSNK1A1	S549	C546W	546	Missense	distal	-3	no	23.961	27.337	EPSD	COSMIC	20.411	Up-regulation
CK1_CK1_CK1-A_CSNK1A1_ST	Q6IE81	JADE1	P48729	CSNK1A1	S549	V542L	542	Missense	distal	-7	no	23.961	24.993	EPSD	COSMIC	20.411	Up-regulation
CK1_CK1_CK1-A_CSNK1A1_ST	Q6IE81	JADE1	P48729	CSNK1A1	S550	L555P	555	Missense	distal	5	no	26.552	26.487	EPSD	COSMIC	20.411	Down-regulation
CK1_CK1_CK1-A_CSNK1A1_ST	Q6IE81	JADE1	P48729	CSNK1A1	S550	S547P	547	Missense	distal	-3	no	26.552	20.364	EPSD	COSMIC	20.411	Loss
CK1_CK1_CK1-A_CSNK1A1_ST	Q6IE81	JADE1	P48729	CSNK1A1	S550	S548P	548	Missense	proximal	-2	no	26.552	24.682	EPSD	COSMIC;GDSC	20.411	Down-regulation
CK1_CK1_CK1-A_CSNK1A1_ST	Q6IE81	JADE1	P48729	CSNK1A1	S550	C546W	546	Missense	distal	-4	no	26.552	28.450	EPSD	COSMIC	20.411	Up-regulation
CK1_CK1_CK1-A_CSNK1A1_ST	Q6IE81	JADE1	P48729	CSNK1A1	S812	S814C	814	Missense	proximal	2	no	21.354	20.369	EPSD	COSMIC	20.411	Loss
CK1_CK1_CK1-A_CSNK1A1_ST	Q6IE81	JADE1	P48729	CSNK1A1	S812	A816P	816	Missense	distal	4	no	21.354	21.341	EPSD	COSMIC	20.411	Down-regulation
CK1_CK1_CK1-A_CSNK1A1_ST	Q6IE81	JADE1	P48729	CSNK1A1	S812	P805H	805	Missense	distal	-7	no	21.354	20.936	EPSD	COSMIC	20.411	Down-regulation
CK1_CK1_CK1-A_CSNK1A1_ST	Q6IE81	JADE1	P48729	CSNK1A1	S814	S814C	814	Missense	central	0	yes	20.867	0.000	EPSD	COSMIC	20.411	Loss
CK1_CK1_CK1-A_CSNK1A1_ST	Q6IE81	JADE1	P48729	CSNK1A1	S814	A816P	816	Missense	proximal	2	no	20.867	20.682	EPSD	COSMIC	20.411	Down-regulation
CK1_CK1_CK1-A_CSNK1A1_ST	P56817	BACE1	P48729	CSNK1A1	S59	F60L	60	Missense	proximal	1	no	22.859	23.178	EPSD	COSMIC	20.411	Up-regulation
CK1_CK1_CK1-A_CSNK1A1_ST	P56817	BACE1	P48729	CSNK1A1	S59	R57C	57	Missense	proximal	-2	no	22.859	22.632	EPSD	COSMIC	20.411	Down-regulation
CK1_CK1_CK1-A_CSNK1A1_ST	Q9NRF8	CTPS2	P48729	CSNK1A1	S568	S574R	574	Missense	distal	6	no	20.414	20.221	PhosphoSitePlus	COSMIC	20.411	Loss
CK1_CK1_CK1-A_CSNK1A1_ST	Q9NRF8	CTPS2	P48729	CSNK1A1	S568	S564G	564	Missense	distal	-4	no	20.414	20.580	PhosphoSitePlus	COSMIC	20.411	Up-regulation
CK1_CK1_CK1-A_CSNK1A1_ST	Q9NRF8	CTPS2	P48729	CSNK1A1	S571	S564G	564	Missense	distal	-7	no	19.397	20.449	EPSD	COSMIC	20.411	Gain
CK1_CK1_CK1-A_CSNK1A1_ST	P12830	CDH1	P48729	CSNK1A1	S770	S770R	770	Missense	central	0	yes	20.520	0.000	EPSD	COSMIC	20.411	Loss
CK1_CK1_CK1-A_CSNK1A1_ST	P12830	CDH1	P48729	CSNK1A1	S770	R774G	774	Missense	distal	4	no	20.520	20.521	EPSD	COSMIC	20.411	Up-regulation
CK1_CK1_CK1-A_CSNK1A1_ST	P12830	CDH1	P48729	CSNK1A1	S770	Q765H	765	Missense	distal	-5	no	20.520	19.224	EPSD	COSMIC	20.411	Loss
CK1_CK1_CK1-A_CSNK1A1_ST	P12830	CDH1	P48729	CSNK1A1	S770	D766N	766	Missense	distal	-4	no	20.520	16.782	EPSD	COSMIC	20.411	Loss
CK1_CK1_CK1-A_CSNK1A1_ST	P12830	CDH1	P48729	CSNK1A1	S770	D764G	764	Missense	distal	-6	no	20.520	20.395	EPSD	COSMIC	20.411	Loss
CK1_CK1_CK1-A_CSNK1A1_ST	P12830	CDH1	P48729	CSNK1A1	S770	R774K	774	Missense	distal	4	no	20.520	20.407	EPSD	COSMIC	20.411	Loss
CK1_CK1_CK1-A_CSNK1A1_ST	P12830	CDH1	P48729	CSNK1A1	S770	E763K	763	Missense	distal	-7	no	20.520	20.758	EPSD	COSMIC	20.411	Up-regulation
CK1_CK1_CK1-A_CSNK1A1_ST	P12830	CDH1	P48729	CSNK1A1	S838	G837E	837	Missense	proximal	-1	no	23.165	23.522	EPSD	COSMIC	20.411	Up-regulation
CK1_CK1_CK1-A_CSNK1A1_ST	P12830	CDH1	P48729	CSNK1A1	S838	D834H	834	Missense	distal	-4	no	23.165	18.096	EPSD	COSMIC	20.411	Loss
CK1_CK1_CK1-A_CSNK1A1_ST	P12830	CDH1	P48729	CSNK1A1	S838	S838G	838	Missense	central	0	yes	23.165	0.000	EPSD	COSMIC	20.411	Loss
CK1_CK1_CK1-A_CSNK1A1_ST	P12830	CDH1	P48729	CSNK1A1	S838	F833Y	833	Missense	distal	-5	no	23.165	23.119	EPSD	COSMIC	20.411	Down-regulation
CK1_CK1_CK1-A_CSNK1A1_ST	P12830	CDH1	P48729	CSNK1A1	S838	S838I	838	Missense	central	0	yes	23.165	0.000	EPSD	COSMIC	20.411	Loss
CK1_CK1_CK1-A_CSNK1A1_ST	P12830	CDH1	P48729	CSNK1A1	S838	A842V	842	Missense	distal	4	no	23.165	23.094	EPSD	COSMIC	20.411	Down-regulation
CK1_CK1_CK1-A_CSNK1A1_ST	P12830	CDH1	P48729	CSNK1A1	S838	L845V	845	Missense	distal	7	no	23.165	23.328	EPSD	COSMIC	20.411	Up-regulation
CK1_CK1_CK1-A_CSNK1A1_ST	P12830	CDH1	P48729	CSNK1A1	S838	S840F	840	Missense	proximal	2	no	23.165	22.143	EPSD	COSMIC	20.411	Down-regulation
CK1_CK1_CK1-A_CSNK1A1_ST	P12830	CDH1	P48729	CSNK1A1	S840	G837E	837	Missense	distal	-3	no	23.761	23.348	EPSD	COSMIC	20.411	Down-regulation
CK1_CK1_CK1-A_CSNK1A1_ST	P12830	CDH1	P48729	CSNK1A1	S840	D834H	834	Missense	distal	-6	no	23.761	22.390	EPSD	COSMIC	20.411	Down-regulation
CK1_CK1_CK1-A_CSNK1A1_ST	P12830	CDH1	P48729	CSNK1A1	S840	S838G	838	Missense	proximal	-2	no	23.761	23.613	EPSD	COSMIC	20.411	Down-regulation
CK1_CK1_CK1-A_CSNK1A1_ST	P12830	CDH1	P48729	CSNK1A1	S840	F833Y	833	Missense	distal	-7	no	23.761	22.711	EPSD	COSMIC	20.411	Down-regulation
CK1_CK1_CK1-A_CSNK1A1_ST	P12830	CDH1	P48729	CSNK1A1	S840	S847F	847	Missense	distal	7	no	23.761	23.949	EPSD	COSMIC	20.411	Up-regulation
CK1_CK1_CK1-A_CSNK1A1_ST	P12830	CDH1	P48729	CSNK1A1	S840	S838I	838	Missense	proximal	-2	no	23.761	21.582	EPSD	COSMIC	20.411	Down-regulation
CK1_CK1_CK1-A_CSNK1A1_ST	P12830	CDH1	P48729	CSNK1A1	S840	A842V	842	Missense	proximal	2	no	23.761	23.318	EPSD	COSMIC	20.411	Down-regulation
CK1_CK1_CK1-A_CSNK1A1_ST	P12830	CDH1	P48729	CSNK1A1	S840	S846T	846	Missense	distal	6	no	23.761	23.658	EPSD	COSMIC	20.411	Down-regulation
CK1_CK1_CK1-A_CSNK1A1_ST	P12830	CDH1	P48729	CSNK1A1	S840	L845V	845	Missense	distal	5	no	23.761	23.799	EPSD	COSMIC	20.411	Up-regulation
CK1_CK1_CK1-A_CSNK1A1_ST	P12830	CDH1	P48729	CSNK1A1	S840	S840F	840	Missense	central	0	yes	23.761	0.000	EPSD	COSMIC	20.411	Loss
CK1_CK1_CK1-A_CSNK1A1_ST	P12830	CDH1	P48729	CSNK1A1	S844	G837E	837	Missense	distal	-7	no	24.956	24.449	PhosphoSitePlus	COSMIC	20.411	Down-regulation
CK1_CK1_CK1-A_CSNK1A1_ST	P12830	CDH1	P48729	CSNK1A1	S844	S838G	838	Missense	distal	-6	no	24.956	25.096	PhosphoSitePlus	COSMIC	20.411	Up-regulation
CK1_CK1_CK1-A_CSNK1A1_ST	P12830	CDH1	P48729	CSNK1A1	S844	S847F	847	Missense	distal	3	no	24.956	22.495	PhosphoSitePlus	COSMIC	20.411	Down-regulation
CK1_CK1_CK1-A_CSNK1A1_ST	P12830	CDH1	P48729	CSNK1A1	S844	S838I	838	Missense	distal	-6	no	24.956	23.949	PhosphoSitePlus	COSMIC	20.411	Down-regulation
CK1_CK1_CK1-A_CSNK1A1_ST	P12830	CDH1	P48729	CSNK1A1	S844	A842V	842	Missense	proximal	-2	no	24.956	23.558	PhosphoSitePlus	COSMIC	20.411	Down-regulation
CK1_CK1_CK1-A_CSNK1A1_ST	P12830	CDH1	P48729	CSNK1A1	S844	S846T	846	Missense	proximal	2	no	24.956	24.164	PhosphoSitePlus	COSMIC	20.411	Down-regulation
CK1_CK1_CK1-A_CSNK1A1_ST	P12830	CDH1	P48729	CSNK1A1	S844	L845V	845	Missense	proximal	1	no	24.956	24.679	PhosphoSitePlus	COSMIC	20.411	Down-regulation
CK1_CK1_CK1-A_CSNK1A1_ST	P12830	CDH1	P48729	CSNK1A1	S844	S840F	840	Missense	distal	-4	no	24.956	23.306	PhosphoSitePlus	COSMIC	20.411	Down-regulation
CK1_CK1_CK1-A_CSNK1A1_ST	P12830	CDH1	P48729	CSNK1A1	S844	S851L	851	Missense	distal	7	no	24.956	24.991	PhosphoSitePlus	COSMIC	20.411	Up-regulation
CK1_CK1_CK1-A_CSNK1A1_ST	P12830	CDH1	P48729	CSNK1A1	S850	E852D	852	Missense	proximal	2	no	24.084	24.275	EPSD	COSMIC	20.411	Up-regulation
CK1_CK1_CK1-A_CSNK1A1_ST	P12830	CDH1	P48729	CSNK1A1	S850	S853P	853	Missense	distal	3	no	24.084	19.819	EPSD	COSMIC	20.411	Loss
CK1_CK1_CK1-A_CSNK1A1_ST	P12830	CDH1	P48729	CSNK1A1	S850	D854Y	854	Missense	distal	4	no	24.084	23.907	EPSD	COSMIC	20.411	Down-regulation
CK1_CK1_CK1-A_CSNK1A1_ST	P12830	CDH1	P48729	CSNK1A1	S850	S847F	847	Missense	distal	-3	no	24.084	18.431	EPSD	COSMIC	20.411	Loss
CK1_CK1_CK1-A_CSNK1A1_ST	P12830	CDH1	P48729	CSNK1A1	S850	E852K	852	Missense	proximal	2	no	24.084	23.108	EPSD	COSMIC	20.411	Down-regulation
CK1_CK1_CK1-A_CSNK1A1_ST	P12830	CDH1	P48729	CSNK1A1	S850	S846T	846	Missense	distal	-4	no	24.084	22.449	EPSD	COSMIC	20.411	Down-regulation
CK1_CK1_CK1-A_CSNK1A1_ST	P12830	CDH1	P48729	CSNK1A1	S850	L845V	845	Missense	distal	-5	no	24.084	22.953	EPSD	COSMIC	20.411	Down-regulation
CK1_CK1_CK1-A_CSNK1A1_ST	P12830	CDH1	P48729	CSNK1A1	S850	Q857K	857	Missense	distal	7	no	24.084	24.082	EPSD	COSMIC	20.411	Down-regulation
CK1_CK1_CK1-A_CSNK1A1_ST	P12830	CDH1	P48729	CSNK1A1	S850	S851L	851	Missense	proximal	1	no	24.084	24.346	EPSD	COSMIC	20.411	Up-regulation
CK1_CK1_CK1-A_CSNK1A1_ST	P12830	CDH1	P48729	CSNK1A1	S853	D858E	858	Missense	distal	5	no	25.072	24.864	EPSD	COSMIC	20.411	Down-regulation
CK1_CK1_CK1-A_CSNK1A1_ST	P12830	CDH1	P48729	CSNK1A1	S853	E852D	852	Missense	proximal	-1	no	25.072	24.442	EPSD	COSMIC	20.411	Down-regulation
CK1_CK1_CK1-A_CSNK1A1_ST	P12830	CDH1	P48729	CSNK1A1	S853	S853P	853	Missense	central	0	yes	25.072	0.000	EPSD	COSMIC	20.411	Loss
CK1_CK1_CK1-A_CSNK1A1_ST	P12830	CDH1	P48729	CSNK1A1	S853	D854Y	854	Missense	proximal	1	no	25.072	24.829	EPSD	COSMIC	20.411	Down-regulation
CK1_CK1_CK1-A_CSNK1A1_ST	P12830	CDH1	P48729	CSNK1A1	S853	Y859C	859	Missense	distal	6	no	25.072	25.223	EPSD	COSMIC	20.411	Up-regulation
CK1_CK1_CK1-A_CSNK1A1_ST	P12830	CDH1	P48729	CSNK1A1	S853	S847F	847	Missense	distal	-6	no	25.072	23.859	EPSD	COSMIC	20.411	Down-regulation
CK1_CK1_CK1-A_CSNK1A1_ST	P12830	CDH1	P48729	CSNK1A1	S853	E852K	852	Missense	proximal	-1	no	25.072	23.431	EPSD	COSMIC	20.411	Down-regulation
CK1_CK1_CK1-A_CSNK1A1_ST	P12830	CDH1	P48729	CSNK1A1	S853	S846T	846	Missense	distal	-7	no	25.072	24.623	EPSD	COSMIC	20.411	Down-regulation
CK1_CK1_CK1-A_CSNK1A1_ST	P12830	CDH1	P48729	CSNK1A1	S853	Q857K	857	Missense	distal	4	no	25.072	25.057	EPSD	COSMIC	20.411	Down-regulation
CK1_CK1_CK1-A_CSNK1A1_ST	P12830	CDH1	P48729	CSNK1A1	S853	S851L	851	Missense	proximal	-2	no	25.072	22.218	EPSD	COSMIC	20.411	Down-regulation
CK1_CK1_CK1-A_CSNK1A1_ST	P51532	SMARCA4	P48729	CSNK1A1	S35	P30S	30	Missense	distal	-5	no	20.007	20.439	PhosphoSitePlus;EPSD	COSMIC	20.411	Gain
CK1_CK1_CK1-A_CSNK1A1_ST	P51532	SMARCA4	P48729	CSNK1A1	S38	S35L	35	Missense	distal	-3	no	24.806	18.212	EPSD	COSMIC	20.411	Loss
CK1_CK1_CK1-A_CSNK1A1_ST	P51532	SMARCA4	P48729	CSNK1A1	S38	S35P	35	Missense	distal	-3	no	24.806	18.619	EPSD	COSMIC	20.411	Loss
CK1_CK1_CK1-A_CSNK1A1_ST	P51532	SMARCA4	P48729	CSNK1A1	S38	S38C	38	Missense	central	0	yes	24.806	0.000	EPSD	COSMIC	20.411	Loss
CK1_CK1_CK1-A_CSNK1A1_ST	P51532	SMARCA4	P48729	CSNK1A1	S38	P45L	45	Missense	distal	7	no	24.806	24.654	EPSD	COSMIC	20.411	Down-regulation
CK1_CK1_CK1-A_CSNK1A1_ST	P51532	SMARCA4	P48729	CSNK1A1	S38	G44R	44	Missense	distal	6	no	24.806	24.595	EPSD	COSMIC	20.411	Down-regulation
CK1_CK1_CK1-A_CSNK1A1_ST	P51532	SMARCA4	P48729	CSNK1A1	S111	S117F	117	Missense	distal	6	no	20.572	19.995	EPSD	COSMIC	20.411	Loss
CK1_CK1_CK1-A_CSNK1A1_ST	P51532	SMARCA4	P48729	CSNK1A1	S147	A152V	152	Missense	distal	5	no	21.551	21.583	EPSD	COSMIC	20.411	Up-regulation
CK1_CK1_CK1-A_CSNK1A1_ST	P51532	SMARCA4	P48729	CSNK1A1	S147	S141P	141	Missense	distal	-6	no	21.551	20.870	EPSD	COSMIC	20.411	Down-regulation
CK1_CK1_CK1-A_CSNK1A1_ST	P51532	SMARCA4	P48729	CSNK1A1	S660	E667K	667	Missense	distal	7	no	27.117	27.246	EPSD	COSMIC	20.411	Up-regulation
CK1_CK1_CK1-A_CSNK1A1_ST	P51532	SMARCA4	P48729	CSNK1A1	S660	R654K	654	Missense	distal	-6	no	27.117	26.697	EPSD	COSMIC	20.411	Down-regulation
CK1_CK1_CK1-A_CSNK1A1_ST	P51532	SMARCA4	P48729	CSNK1A1	S662	E667K	667	Missense	distal	5	no	21.031	21.475	EPSD	COSMIC	20.411	Up-regulation
CK1_CK1_CK1-A_CSNK1A1_ST	P51532	SMARCA4	P48729	CSNK1A1	S662	E668K	668	Missense	distal	6	no	21.031	20.943	EPSD	COSMIC	20.411	Down-regulation
CK1_CK1_CK1-A_CSNK1A1_ST	P51532	SMARCA4	P48729	CSNK1A1	S695	D694N	694	Missense	proximal	-1	no	20.891	20.327	EPSD	COSMIC	20.411	Loss
CK1_CK1_CK1-A_CSNK1A1_ST	P51532	SMARCA4	P48729	CSNK1A1	S695	D692Y	692	Missense	distal	-3	no	20.891	14.545	EPSD	COSMIC	20.411	Loss
CK1_CK1_CK1-A_CSNK1A1_ST	P51532	SMARCA4	P48729	CSNK1A1	S695	D697G	697	Missense	proximal	2	no	20.891	21.095	EPSD	COSMIC	20.411	Up-regulation
CK1_CK1_CK1-A_CSNK1A1_ST	P51532	SMARCA4	P48729	CSNK1A1	S699	D694N	694	Missense	distal	-5	no	25.806	25.556	EPSD	COSMIC	20.411	Down-regulation
CK1_CK1_CK1-A_CSNK1A1_ST	P51532	SMARCA4	P48729	CSNK1A1	S699	R704Q	704	Missense	distal	5	no	25.806	25.272	EPSD	COSMIC	20.411	Down-regulation
CK1_CK1_CK1-A_CSNK1A1_ST	P51532	SMARCA4	P48729	CSNK1A1	S699	D692Y	692	Missense	distal	-7	no	25.806	24.076	EPSD	COSMIC	20.411	Down-regulation
CK1_CK1_CK1-A_CSNK1A1_ST	P51532	SMARCA4	P48729	CSNK1A1	S699	A703T	703	Missense	distal	4	no	25.806	25.794	EPSD	COSMIC	20.411	Down-regulation
CK1_CK1_CK1-A_CSNK1A1_ST	P51532	SMARCA4	P48729	CSNK1A1	S699	D697G	697	Missense	proximal	-2	no	25.806	25.773	EPSD	COSMIC	20.411	Down-regulation
CK1_CK1_CK1-A_CSNK1A1_ST	P51532	SMARCA4	P48729	CSNK1A1	S746	A747T	747	Missense	proximal	1	no	21.090	21.134	EPSD	COSMIC	20.411	Up-regulation
CK1_CK1_CK1-A_CSNK1A1_ST	P51532	SMARCA4	P48729	CSNK1A1	S746	K744E	744	Missense	proximal	-2	no	21.090	22.403	EPSD	COSMIC	20.411	Up-regulation
CK1_CK1_CK1-A_CSNK1A1_ST	P51532	SMARCA4	P48729	CSNK1A1	S746	A747V	747	Missense	proximal	1	no	21.090	21.112	EPSD	COSMIC	20.411	Up-regulation
CK1_CK1_CK1-A_CSNK1A1_ST	P51532	SMARCA4	P48729	CSNK1A1	S746	E740D	740	Missense	distal	-6	no	21.090	22.026	EPSD	COSMIC	20.411	Up-regulation
CK1_CK1_CK1-A_CSNK1A1_ST	P51532	SMARCA4	P48729	CSNK1A1	S1238	D1235Y	1235	Missense	distal	-3	no	22.517	16.170	EPSD	COSMIC;GDSC;CCLE	20.411	Loss
CK1_CK1_CK1-A_CSNK1A1_ST	P51532	SMARCA4	P48729	CSNK1A1	S1238	G1232D	1232	Missense	distal	-6	no	22.517	22.642	EPSD	COSMIC;GDSC;CCLE	20.411	Up-regulation
CK1_CK1_CK1-A_CSNK1A1_ST	P51532	SMARCA4	P48729	CSNK1A1	S1238	F1234V	1234	Missense	distal	-4	no	22.517	21.383	EPSD	COSMIC	20.411	Down-regulation
CK1_CK1_CK1-A_CSNK1A1_ST	P51532	SMARCA4	P48729	CSNK1A1	S1238	R1243L	1243	Missense	distal	5	no	22.517	22.420	EPSD	COSMIC	20.411	Down-regulation
CK1_CK1_CK1-A_CSNK1A1_ST	P51532	SMARCA4	P48729	CSNK1A1	S1238	A1245T	1245	Missense	distal	7	no	22.517	22.497	EPSD	COSMIC	20.411	Down-regulation
CK1_CK1_CK1-A_CSNK1A1_ST	P51532	SMARCA4	P48729	CSNK1A1	S1238	R1243G	1243	Missense	distal	5	no	22.517	22.419	EPSD	COSMIC	20.411	Down-regulation
CK1_CK1_CK1-A_CSNK1A1_ST	P51532	SMARCA4	P48729	CSNK1A1	S1238	R1243P	1243	Missense	distal	5	no	22.517	22.355	EPSD	COSMIC	20.411	Down-regulation
CK1_CK1_CK1-A_CSNK1A1_ST	P51532	SMARCA4	P48729	CSNK1A1	S1238	D1235G	1235	Missense	distal	-3	no	22.517	20.454	EPSD	COSMIC	20.411	Down-regulation
CK1_CK1_CK1-A_CSNK1A1_ST	P51532	SMARCA4	P48729	CSNK1A1	S1238	S1238F	1238	Missense	central	0	yes	22.517	0.000	EPSD	COSMIC	20.411	Loss
CK1_CK1_CK1-A_CSNK1A1_ST	P51532	SMARCA4	P48729	CSNK1A1	S1238	F1234I	1234	Missense	distal	-4	no	22.517	21.968	EPSD	COSMIC	20.411	Down-regulation
CK1_CK1_CK1-A_CSNK1A1_ST	P51532	SMARCA4	P48729	CSNK1A1	S1238	G1232C	1232	Missense	distal	-6	no	22.517	21.523	EPSD	COSMIC	20.411	Down-regulation
CK1_CK1_CK1-A_CSNK1A1_ST	P51532	SMARCA4	P48729	CSNK1A1	S1238	D1235E	1235	Missense	distal	-3	no	22.517	20.041	EPSD	COSMIC	20.411	Loss
CK1_CK1_CK1-A_CSNK1A1_ST	P51532	SMARCA4	P48729	CSNK1A1	S1238	M1233I	1233	Missense	distal	-5	no	22.517	21.759	EPSD	COSMIC;GDSC;CCLE	20.411	Down-regulation
CK1_CK1_CK1-A_CSNK1A1_ST	P51532	SMARCA4	P48729	CSNK1A1	S1238	R1244H	1244	Missense	distal	6	no	22.517	22.446	EPSD	COSMIC;CCLE	20.411	Down-regulation
CK1_CK1_CK1-A_CSNK1A1_ST	P51532	SMARCA4	P48729	CSNK1A1	S1238	S1240C	1240	Missense	proximal	2	no	22.517	21.532	EPSD	COSMIC	20.411	Down-regulation
CK1_CK1_CK1-A_CSNK1A1_ST	P51532	SMARCA4	P48729	CSNK1A1	S1239	D1235Y	1235	Missense	distal	-4	no	21.136	17.589	EPSD	COSMIC;GDSC;CCLE	20.411	Loss
CK1_CK1_CK1-A_CSNK1A1_ST	P51532	SMARCA4	P48729	CSNK1A1	S1239	G1232D	1232	Missense	distal	-7	no	21.136	20.344	EPSD	COSMIC;GDSC;CCLE	20.411	Loss
CK1_CK1_CK1-A_CSNK1A1_ST	P51532	SMARCA4	P48729	CSNK1A1	S1239	F1234V	1234	Missense	distal	-5	no	21.136	21.277	EPSD	COSMIC	20.411	Up-regulation
CK1_CK1_CK1-A_CSNK1A1_ST	P51532	SMARCA4	P48729	CSNK1A1	S1239	R1243L	1243	Missense	distal	4	no	21.136	21.137	EPSD	COSMIC	20.411	Up-regulation
CK1_CK1_CK1-A_CSNK1A1_ST	P51532	SMARCA4	P48729	CSNK1A1	S1239	A1245T	1245	Missense	distal	6	no	21.136	21.390	EPSD	COSMIC	20.411	Up-regulation
CK1_CK1_CK1-A_CSNK1A1_ST	P51532	SMARCA4	P48729	CSNK1A1	S1239	R1243G	1243	Missense	distal	4	no	21.136	21.137	EPSD	COSMIC	20.411	Up-regulation
CK1_CK1_CK1-A_CSNK1A1_ST	P51532	SMARCA4	P48729	CSNK1A1	S1239	R1243P	1243	Missense	distal	4	no	21.136	21.070	EPSD	COSMIC	20.411	Down-regulation
CK1_CK1_CK1-A_CSNK1A1_ST	P51532	SMARCA4	P48729	CSNK1A1	S1239	D1235G	1235	Missense	distal	-4	no	21.136	20.307	EPSD	COSMIC	20.411	Loss
CK1_CK1_CK1-A_CSNK1A1_ST	P51532	SMARCA4	P48729	CSNK1A1	S1239	S1238F	1238	Missense	proximal	-1	no	21.136	20.434	EPSD	COSMIC	20.411	Down-regulation
CK1_CK1_CK1-A_CSNK1A1_ST	P51532	SMARCA4	P48729	CSNK1A1	S1239	F1234I	1234	Missense	distal	-5	no	21.136	22.864	EPSD	COSMIC	20.411	Up-regulation
CK1_CK1_CK1-A_CSNK1A1_ST	P51532	SMARCA4	P48729	CSNK1A1	S1239	G1232C	1232	Missense	distal	-7	no	21.136	19.428	EPSD	COSMIC	20.411	Loss
CK1_CK1_CK1-A_CSNK1A1_ST	P51532	SMARCA4	P48729	CSNK1A1	S1239	D1235E	1235	Missense	distal	-4	no	21.136	20.700	EPSD	COSMIC	20.411	Down-regulation
CK1_CK1_CK1-A_CSNK1A1_ST	P51532	SMARCA4	P48729	CSNK1A1	S1239	M1233I	1233	Missense	distal	-6	no	21.136	20.268	EPSD	COSMIC;GDSC;CCLE	20.411	Loss
CK1_CK1_CK1-A_CSNK1A1_ST	P51532	SMARCA4	P48729	CSNK1A1	S1239	R1244H	1244	Missense	distal	5	no	21.136	21.200	EPSD	COSMIC;CCLE	20.411	Up-regulation
CK1_CK1_CK1-A_CSNK1A1_ST	P51532	SMARCA4	P48729	CSNK1A1	S1239	S1240C	1240	Missense	proximal	1	no	21.136	20.932	EPSD	COSMIC	20.411	Down-regulation
CK1_CK1_CK1-A_CSNK1A1_ST	P51532	SMARCA4	P48729	CSNK1A1	S1421	R1415W	1415	Missense	distal	-6	no	20.493	20.353	EPSD	COSMIC	20.411	Loss
CK1_CK1_CK1-A_CSNK1A1_ST	P51532	SMARCA4	P48729	CSNK1A1	S1421	R1415Q	1415	Missense	distal	-6	no	20.493	20.682	EPSD	COSMIC	20.411	Up-regulation
CK1_CK1_CK1-A_CSNK1A1_ST	P51532	SMARCA4	P48729	CSNK1A1	S1421	G1420A	1420	Missense	proximal	-1	no	20.493	19.663	EPSD	COSMIC	20.411	Loss
CK1_CK1_CK1-A_CSNK1A1_ST	P51532	SMARCA4	P48729	CSNK1A1	S1421	P1424L	1424	Missense	distal	3	no	20.493	21.006	EPSD	COSMIC	20.411	Up-regulation
CK1_CK1_CK1-A_CSNK1A1_ST	P51532	SMARCA4	P48729	CSNK1A1	S1421	D1418G	1418	Missense	distal	-3	no	20.493	18.431	EPSD	COSMIC	20.411	Loss
CK1_CK1_CK1-A_CSNK1A1_ST	P51532	SMARCA4	P48729	CSNK1A1	S1421	T1423A	1423	Missense	proximal	2	no	20.493	20.455	EPSD	COSMIC	20.411	Down-regulation
CK1_CK1_CK1-A_CSNK1A1_ST	P51532	SMARCA4	P48729	CSNK1A1	S1421	S1421F	1421	Missense	central	0	yes	20.493	0.000	EPSD	COSMIC	20.411	Loss
CK1_CK1_CK1-A_CSNK1A1_ST	P51532	SMARCA4	P48729	CSNK1A1	S1421	T1425A	1425	Missense	distal	4	no	20.493	20.505	EPSD	COSMIC	20.411	Up-regulation
CK1_CK1_CK1-A_CSNK1A1_ST	P51532	SMARCA4	P48729	CSNK1A1	S1421	R1415C	1415	Missense	distal	-6	no	20.493	20.168	EPSD	COSMIC	20.411	Loss
CK1_CK1_CK1-A_CSNK1A1_ST	P51532	SMARCA4	P48729	CSNK1A1	S1570	K1566N	1566	Missense	distal	-4	no	20.161	20.557	EPSD	COSMIC;CCLE	20.411	Gain
CK1_CK1_CK1-A_CSNK1A1_ST	P51532	SMARCA4	P48729	CSNK1A1	S1575	E1577Q	1577	Missense	proximal	2	no	27.501	27.235	EPSD	COSMIC	20.411	Down-regulation
CK1_CK1_CK1-A_CSNK1A1_ST	P51532	SMARCA4	P48729	CSNK1A1	S1575	G1572S	1572	Missense	distal	-3	no	27.501	29.192	EPSD	COSMIC	20.411	Up-regulation
CK1_CK1_CK1-A_CSNK1A1_ST	P51532	SMARCA4	P48729	CSNK1A1	S1575	E1576V	1576	Missense	proximal	1	no	27.501	27.185	EPSD	COSMIC	20.411	Down-regulation
CK1_CK1_CK1-A_CSNK1A1_ST	P51532	SMARCA4	P48729	CSNK1A1	S1575	E1576Q	1576	Missense	proximal	1	no	27.501	27.485	EPSD	COSMIC	20.411	Down-regulation
CK1_CK1_CK1-A_CSNK1A1_ST	P51532	SMARCA4	P48729	CSNK1A1	S1575	E1579Q	1579	Missense	distal	4	no	27.501	27.327	EPSD	COSMIC	20.411	Down-regulation
CK1_CK1_CK1-A_CSNK1A1_ST	P51532	SMARCA4	P48729	CSNK1A1	S1575	E1578V	1578	Missense	distal	3	no	27.501	24.334	EPSD	COSMIC	20.411	Down-regulation
CK1_CK1_CK1-A_CSNK1A1_ST	P51532	SMARCA4	P48729	CSNK1A1	S1575	G1581S	1581	Missense	distal	6	no	27.501	27.483	EPSD	COSMIC	20.411	Down-regulation
CK1_CK1_CK1-A_CSNK1A1_ST	P51532	SMARCA4	P48729	CSNK1A1	S1586	S1590F	1590	Missense	distal	4	no	24.243	24.156	EPSD	COSMIC	20.411	Down-regulation
CK1_CK1_CK1-A_CSNK1A1_ST	P51532	SMARCA4	P48729	CSNK1A1	S1586	V1593M	1593	Missense	distal	7	no	24.243	24.099	EPSD	COSMIC	20.411	Down-regulation
CK1_CK1_CK1-A_CSNK1A1_ST	P51532	SMARCA4	P48729	CSNK1A1	S1586	S1586F	1586	Missense	central	0	yes	24.243	0.000	EPSD	COSMIC	20.411	Loss
CK1_CK1_CK1-A_CSNK1A1_ST	P51532	SMARCA4	P48729	CSNK1A1	S1586	S1592F	1592	Missense	distal	6	no	24.243	23.666	EPSD	COSMIC	20.411	Down-regulation
CK1_CK1_CK1-A_CSNK1A1_ST	P51532	SMARCA4	P48729	CSNK1A1	S1586	V1593I	1593	Missense	distal	7	no	24.243	23.954	EPSD	COSMIC	20.411	Down-regulation
CK1_CK1_CK1-A_CSNK1A1_ST	P51532	SMARCA4	P48729	CSNK1A1	S1586	E1584K	1584	Missense	proximal	-2	no	24.243	22.929	EPSD	COSMIC	20.411	Down-regulation
CK1_CK1_CK1-A_CSNK1A1_ST	P51532	SMARCA4	P48729	CSNK1A1	S1586	E1579Q	1579	Missense	distal	-7	no	24.243	23.785	EPSD	COSMIC	20.411	Down-regulation
CK1_CK1_CK1-A_CSNK1A1_ST	P51532	SMARCA4	P48729	CSNK1A1	S1586	S1586G	1586	Missense	central	0	yes	24.243	0.000	EPSD	COSMIC	20.411	Loss
CK1_CK1_CK1-A_CSNK1A1_ST	P51532	SMARCA4	P48729	CSNK1A1	S1586	S1586N	1586	Missense	central	0	yes	24.243	0.000	EPSD	COSMIC	20.411	Loss
CK1_CK1_CK1-A_CSNK1A1_ST	P51532	SMARCA4	P48729	CSNK1A1	S1586	G1581S	1581	Missense	distal	-5	no	24.243	23.949	EPSD	COSMIC	20.411	Down-regulation
CK1_CK1_CK1-A_CSNK1A1_ST	P51532	SMARCA4	P48729	CSNK1A1	S1588	S1590F	1590	Missense	proximal	2	no	21.835	20.813	EPSD	COSMIC	20.411	Down-regulation
CK1_CK1_CK1-A_CSNK1A1_ST	P51532	SMARCA4	P48729	CSNK1A1	S1588	V1593M	1593	Missense	distal	5	no	21.835	21.602	EPSD	COSMIC	20.411	Down-regulation
CK1_CK1_CK1-A_CSNK1A1_ST	P51532	SMARCA4	P48729	CSNK1A1	S1588	S1586F	1586	Missense	proximal	-2	no	21.835	19.969	EPSD	COSMIC	20.411	Loss
CK1_CK1_CK1-A_CSNK1A1_ST	P51532	SMARCA4	P48729	CSNK1A1	S1588	S1592F	1592	Missense	distal	4	no	21.835	21.748	EPSD	COSMIC	20.411	Down-regulation
CK1_CK1_CK1-A_CSNK1A1_ST	P51532	SMARCA4	P48729	CSNK1A1	S1588	V1593I	1593	Missense	distal	5	no	21.835	21.529	EPSD	COSMIC	20.411	Down-regulation
CK1_CK1_CK1-A_CSNK1A1_ST	P51532	SMARCA4	P48729	CSNK1A1	S1588	E1584K	1584	Missense	distal	-4	no	21.835	18.138	EPSD	COSMIC	20.411	Loss
CK1_CK1_CK1-A_CSNK1A1_ST	P51532	SMARCA4	P48729	CSNK1A1	S1588	V1595I	1595	Missense	distal	7	no	21.835	21.546	EPSD	COSMIC	20.411	Down-regulation
CK1_CK1_CK1-A_CSNK1A1_ST	P51532	SMARCA4	P48729	CSNK1A1	S1588	S1586G	1586	Missense	proximal	-2	no	21.835	21.686	EPSD	COSMIC	20.411	Down-regulation
CK1_CK1_CK1-A_CSNK1A1_ST	P51532	SMARCA4	P48729	CSNK1A1	S1588	V1595M	1595	Missense	distal	7	no	21.835	21.691	EPSD	COSMIC	20.411	Down-regulation
CK1_CK1_CK1-A_CSNK1A1_ST	P51532	SMARCA4	P48729	CSNK1A1	S1588	S1586N	1586	Missense	proximal	-2	no	21.835	19.593	EPSD	COSMIC	20.411	Loss
CK1_CK1_CK1-A_CSNK1A1_ST	P51532	SMARCA4	P48729	CSNK1A1	S1588	G1581S	1581	Missense	distal	-7	no	21.835	20.783	EPSD	COSMIC	20.411	Down-regulation
CK1_CK1_CK1-A_CSNK1A1_ST	P51532	SMARCA4	P48729	CSNK1A1	S1590	V1593I	1593	Missense	distal	3	no	19.769	21.098	EPSD	COSMIC	20.411	Gain
CK1_CK1_CK1-A_CSNK1A1_ST	P51532	SMARCA4	P48729	CSNK1A1	S1617	R1613Q	1613	Missense	distal	-4	no	19.781	21.996	EPSD	COSMIC	20.411	Gain
CK1_CK1_CK1-A_CSNK1A1_ST	P51532	SMARCA4	P48729	CSNK1A1	S1617	R1614W	1614	Missense	distal	-3	no	19.781	23.051	EPSD	COSMIC	20.411	Gain
CK1_CK1_CK1-A_CSNK1A1_ST	P51532	SMARCA4	P48729	CSNK1A1	S1617	R1613W	1613	Missense	distal	-4	no	19.781	21.013	EPSD	COSMIC	20.411	Gain
CK1_CK1_CK1-A_CSNK1A1_ST	P51532	SMARCA4	P48729	CSNK1A1	S1640	D1638H	1638	Missense	proximal	-2	no	21.137	18.542	EPSD	COSMIC	20.411	Loss
CK1_CK1_CK1-A_CSNK1A1_ST	P51532	SMARCA4	P48729	CSNK1A1	S1640	E1646K	1646	Missense	distal	6	no	21.137	21.050	EPSD	COSMIC	20.411	Down-regulation
CK1_CK1_CK1-A_CSNK1A1_ST	P51532	SMARCA4	P48729	CSNK1A1	S1640	E1633A	1633	Missense	distal	-7	no	21.137	21.114	EPSD	COSMIC	20.411	Down-regulation
CK1_CK1_CK1-A_CSNK1A1_ST	P51532	SMARCA4	P48729	CSNK1A1	S1640	R1639C	1639	Missense	proximal	-1	no	21.137	20.422	EPSD	COSMIC	20.411	Down-regulation
CK1_CK1_CK1-A_CSNK1A1_ST	P51532	SMARCA4	P48729	CSNK1A1	S1640	E1645K	1645	Missense	distal	5	no	21.137	21.581	EPSD	COSMIC	20.411	Up-regulation
CK1_CK1_CK1-A_CSNK1A1_ST	P51532	SMARCA4	P48729	CSNK1A1	S1644	D1638H	1638	Missense	distal	-6	no	20.946	19.575	EPSD	COSMIC	20.411	Loss
CK1_CK1_CK1-A_CSNK1A1_ST	P51532	SMARCA4	P48729	CSNK1A1	S1644	E1646K	1646	Missense	proximal	2	no	20.946	19.970	EPSD	COSMIC	20.411	Loss
CK1_CK1_CK1-A_CSNK1A1_ST	P51532	SMARCA4	P48729	CSNK1A1	S1644	R1639C	1639	Missense	distal	-5	no	20.946	20.513	EPSD	COSMIC	20.411	Down-regulation
CK1_CK1_CK1-A_CSNK1A1_ST	P51532	SMARCA4	P48729	CSNK1A1	S1644	E1645K	1645	Missense	proximal	1	no	20.946	20.486	EPSD	COSMIC	20.411	Down-regulation
CK1_CK1_CK1-A_CSNK1A1_ST	P16220	CREB1	P48729	CSNK1A1	S111	S117N	117	Missense	distal	6	no	24.754	24.537	PhosphoSitePlus;EPSD	COSMIC	20.411	Down-regulation
CK1_CK1_CK1-A_CSNK1A1_ST	P16220	CREB1	P48729	CSNK1A1	S111	V118L	118	Missense	distal	7	no	24.754	24.591	PhosphoSitePlus;EPSD	COSMIC	20.411	Down-regulation
CK1_CK1_CK1-A_CSNK1A1_ST	P16220	CREB1	P48729	CSNK1A1	S111	E109K	109	Missense	proximal	-2	no	24.754	23.440	PhosphoSitePlus;EPSD	COSMIC	20.411	Down-regulation
CK1_CK1_CK1-A_CSNK1A1_ST	P16220	CREB1	P48729	CSNK1A1	S111	V118I	118	Missense	distal	7	no	24.754	24.465	PhosphoSitePlus;EPSD	COSMIC	20.411	Down-regulation
CK1_CK1_CK1-A_CSNK1A1_ST	P16220	CREB1	P48729	CSNK1A1	S114	S117N	117	Missense	distal	3	no	26.239	23.761	EPSD;PhosphoSitePlus	COSMIC	20.411	Down-regulation
CK1_CK1_CK1-A_CSNK1A1_ST	P16220	CREB1	P48729	CSNK1A1	S114	V118L	118	Missense	distal	4	no	26.239	26.363	EPSD;PhosphoSitePlus	COSMIC	20.411	Up-regulation
CK1_CK1_CK1-A_CSNK1A1_ST	P16220	CREB1	P48729	CSNK1A1	S114	E109K	109	Missense	distal	-5	no	26.239	25.621	EPSD;PhosphoSitePlus	COSMIC	20.411	Down-regulation
CK1_CK1_CK1-A_CSNK1A1_ST	P16220	CREB1	P48729	CSNK1A1	S114	V118I	118	Missense	distal	4	no	26.239	26.355	EPSD;PhosphoSitePlus	COSMIC	20.411	Up-regulation
CK1_CK1_CK1-A_CSNK1A1_ST	P16220	CREB1	P48729	CSNK1A1	S117	S117N	117	Missense	central	0	yes	21.395	0.000	EPSD	COSMIC	20.411	Loss
CK1_CK1_CK1-A_CSNK1A1_ST	P16220	CREB1	P48729	CSNK1A1	S117	R124Q	124	Missense	distal	7	no	21.395	21.294	EPSD	COSMIC	20.411	Down-regulation
CK1_CK1_CK1-A_CSNK1A1_ST	P16220	CREB1	P48729	CSNK1A1	S117	V118L	118	Missense	proximal	1	no	21.395	21.671	EPSD	COSMIC	20.411	Up-regulation
CK1_CK1_CK1-A_CSNK1A1_ST	P16220	CREB1	P48729	CSNK1A1	S117	V118I	118	Missense	proximal	1	no	21.395	21.582	EPSD	COSMIC	20.411	Up-regulation
CK1_CK1_CK1-A_CSNK1A1_ST	Q9UKV8	AGO2	P48729	CSNK1A1	S834	A841S	841	Missense	distal	7	no	23.054	22.975	PhosphoSitePlus;EPSD	COSMIC	20.411	Down-regulation
CK1_CK1_CK1-A_CSNK1A1_ST	P11308	ERG	P48729	CSNK1A1	S46	S45F	45	Missense	proximal	-1	no	29.392	28.689	EPSD;PhosphoSitePlus	COSMIC	20.411	Down-regulation
CK1_CK1_CK1-A_CSNK1A1_ST	P11308	ERG	P48729	CSNK1A1	S46	D47N	47	Missense	proximal	1	no	29.392	29.162	EPSD;PhosphoSitePlus	COSMIC	20.411	Down-regulation
CK1_CK1_CK1-A_CSNK1A1_ST	P11308	ERG	P48729	CSNK1A1	S46	E39Q	39	Missense	distal	-7	no	29.392	28.934	EPSD;PhosphoSitePlus	COSMIC	20.411	Down-regulation
CK1_CK1_CK1-A_CSNK1A1_ST	P11308	ERG	P48729	CSNK1A1	S46	A42V	42	Missense	distal	-4	no	29.392	28.207	EPSD;PhosphoSitePlus	COSMIC;GDSC;CCLE	20.411	Down-regulation
CK1_CK1_CK1-A_CSNK1A1_ST	P11308	ERG	P48729	CSNK1A1	S46	S52F	52	Missense	distal	6	no	29.392	28.814	EPSD;PhosphoSitePlus	COSMIC	20.411	Down-regulation
CK1_CK1_CK1-A_CSNK1A1_ST	P11308	ERG	P48729	CSNK1A1	S46	S44F	44	Missense	proximal	-2	no	29.392	27.525	EPSD;PhosphoSitePlus	COSMIC	20.411	Down-regulation
CK1_CK1_CK1-A_CSNK1A1_ST	P11308	ERG	P48729	CSNK1A1	S85	V82M	82	Missense	distal	-3	no	18.197	21.624	EPSD	COSMIC	20.411	Gain
CK1_CK1_CK1-A_CSNK1A1_ST	P11308	ERG	P48729	CSNK1A1	S88	P89S	89	Missense	proximal	1	no	22.835	22.683	EPSD	COSMIC	20.411	Down-regulation
CK1_CK1_CK1-A_CSNK1A1_ST	P11308	ERG	P48729	CSNK1A1	S88	G84D	84	Missense	distal	-4	no	22.835	23.664	EPSD	COSMIC	20.411	Up-regulation
CK1_CK1_CK1-A_CSNK1A1_ST	P11308	ERG	P48729	CSNK1A1	S88	V82M	82	Missense	distal	-6	no	22.835	23.863	EPSD	COSMIC	20.411	Up-regulation
CK1_CK1_CK1-A_CSNK1A1_ST	P11308	ERG	P48729	CSNK1A1	S93	P89S	89	Missense	distal	-4	no	19.194	21.886	EPSD	COSMIC	20.411	Gain
CK1_CK1_CK1-A_CSNK1A1_ST	P11308	ERG	P48729	CSNK1A1	S113	N110S	110	Missense	distal	-3	no	16.217	21.126	EPSD	COSMIC	20.411	Gain
CK1_CK1_CK1-A_CSNK1A1_ST	P25054	APC	P48729	CSNK1A1	S62	A59G	59	Missense	distal	-3	no	19.852	22.617	EPSD	COSMIC	20.411	Gain
CK1_CK1_CK1-A_CSNK1A1_ST	P25054	APC	P48729	CSNK1A1	S92	R88W	88	Missense	distal	-4	no	19.937	21.169	EPSD	COSMIC	20.411	Gain
CK1_CK1_CK1-A_CSNK1A1_ST	P25054	APC	P48729	CSNK1A1	S95	K90N	90	Missense	distal	-5	no	20.190	21.278	EPSD	COSMIC	20.411	Gain
CK1_CK1_CK1-A_CSNK1A1_ST	P25054	APC	P48729	CSNK1A1	S98	S95F	95	Missense	distal	-3	no	23.082	17.430	EPSD	COSMIC	20.411	Loss
CK1_CK1_CK1-A_CSNK1A1_ST	P25054	APC	P48729	CSNK1A1	S98	R94H	94	Missense	distal	-4	no	23.082	21.042	EPSD	COSMIC	20.411	Down-regulation
CK1_CK1_CK1-A_CSNK1A1_ST	P25054	APC	P48729	CSNK1A1	S98	R99W	99	Missense	proximal	1	no	23.082	22.743	EPSD	COSMIC	20.411	Down-regulation
CK1_CK1_CK1-A_CSNK1A1_ST	P25054	APC	P48729	CSNK1A1	S98	R94C	94	Missense	distal	-4	no	23.082	22.416	EPSD	COSMIC;GDSC;CCLE	20.411	Down-regulation
CK1_CK1_CK1-A_CSNK1A1_ST	P25054	APC	P48729	CSNK1A1	S98	S105G	105	Missense	distal	7	no	23.082	23.104	EPSD	COSMIC	20.411	Up-regulation
CK1_CK1_CK1-A_CSNK1A1_ST	P25054	APC	P48729	CSNK1A1	S102	R99W	99	Missense	distal	-3	no	19.718	22.987	EPSD	COSMIC	20.411	Gain
CK1_CK1_CK1-A_CSNK1A1_ST	P25054	APC	P48729	CSNK1A1	S107	C110Y	110	Missense	distal	3	no	22.831	24.070	EPSD	COSMIC	20.411	Up-regulation
CK1_CK1_CK1-A_CSNK1A1_ST	P25054	APC	P48729	CSNK1A1	S107	S105G	105	Missense	proximal	-2	no	22.831	22.682	EPSD	COSMIC	20.411	Down-regulation
CK1_CK1_CK1-A_CSNK1A1_ST	P25054	APC	P48729	CSNK1A1	S130	S130R	130	Missense	central	0	yes	23.805	0.000	EPSD	COSMIC	20.411	Loss
CK1_CK1_CK1-A_CSNK1A1_ST	P25054	APC	P48729	CSNK1A1	S130	S130G	130	Missense	central	0	yes	23.805	0.000	EPSD	COSMIC;GDSC	20.411	Loss
CK1_CK1_CK1-A_CSNK1A1_ST	P25054	APC	P48729	CSNK1A1	S130	G126R	126	Missense	distal	-4	no	23.805	21.606	EPSD	COSMIC	20.411	Down-regulation
CK1_CK1_CK1-A_CSNK1A1_ST	P25054	APC	P48729	CSNK1A1	S130	E129Q	129	Missense	proximal	-1	no	23.805	23.280	EPSD	COSMIC	20.411	Down-regulation
CK1_CK1_CK1-A_CSNK1A1_ST	P25054	APC	P48729	CSNK1A1	S130	R128K	128	Missense	proximal	-2	no	23.805	23.580	EPSD	COSMIC	20.411	Down-regulation
CK1_CK1_CK1-A_CSNK1A1_ST	P25054	APC	P48729	CSNK1A1	S130	N125K	125	Missense	distal	-5	no	23.805	22.717	EPSD	COSMIC;CCLE	20.411	Down-regulation
CK1_CK1_CK1-A_CSNK1A1_ST	P25054	APC	P48729	CSNK1A1	S130	N125I	125	Missense	distal	-5	no	23.805	23.804	EPSD	COSMIC	20.411	Down-regulation
CK1_CK1_CK1-A_CSNK1A1_ST	P25054	APC	P48729	CSNK1A1	S293	V291F	291	Missense	proximal	-2	no	23.718	24.208	EPSD	COSMIC	20.411	Up-regulation
CK1_CK1_CK1-A_CSNK1A1_ST	P25054	APC	P48729	CSNK1A1	S293	L292F	292	Missense	proximal	-1	no	23.718	23.291	EPSD	COSMIC	20.411	Down-regulation
CK1_CK1_CK1-A_CSNK1A1_ST	P25054	APC	P48729	CSNK1A1	S293	T297A	297	Missense	distal	4	no	23.718	23.729	EPSD	COSMIC	20.411	Up-regulation
CK1_CK1_CK1-A_CSNK1A1_ST	P25054	APC	P48729	CSNK1A1	S296	L292F	292	Missense	distal	-4	no	18.686	20.843	EPSD	COSMIC	20.411	Gain
CK1_CK1_CK1-A_CSNK1A1_ST	P25054	APC	P48729	CSNK1A1	S780	N778D	778	Missense	proximal	-2	no	19.051	21.176	EPSD	COSMIC	20.411	Gain
CK1_CK1_CK1-A_CSNK1A1_ST	P25054	APC	P48729	CSNK1A1	S846	L852S	852	Missense	distal	6	no	27.884	28.024	EPSD	COSMIC	20.411	Up-regulation
CK1_CK1_CK1-A_CSNK1A1_ST	P25054	APC	P48729	CSNK1A1	S846	L852M	852	Missense	distal	6	no	27.884	28.102	EPSD	COSMIC	20.411	Up-regulation
CK1_CK1_CK1-A_CSNK1A1_ST	P25054	APC	P48729	CSNK1A1	S846	E853K	853	Missense	distal	7	no	27.884	28.013	EPSD	COSMIC	20.411	Up-regulation
CK1_CK1_CK1-A_CSNK1A1_ST	P25054	APC	P48729	CSNK1A1	S905	T909I	909	Missense	distal	4	no	23.470	23.527	EPSD	COSMIC	20.411	Up-regulation
CK1_CK1_CK1-A_CSNK1A1_ST	P25054	APC	P48729	CSNK1A1	S905	H898Y	898	Missense	distal	-7	no	23.470	23.085	EPSD	COSMIC	20.411	Down-regulation
CK1_CK1_CK1-A_CSNK1A1_ST	P25054	APC	P48729	CSNK1A1	S905	S905G	905	Missense	central	0	yes	23.470	0.000	EPSD	COSMIC	20.411	Loss
CK1_CK1_CK1-A_CSNK1A1_ST	P25054	APC	P48729	CSNK1A1	S905	T909A	909	Missense	distal	4	no	23.470	23.482	EPSD	COSMIC	20.411	Up-regulation
CK1_CK1_CK1-A_CSNK1A1_ST	P25054	APC	P48729	CSNK1A1	S905	S908T	908	Missense	distal	3	no	23.470	21.037	EPSD	COSMIC	20.411	Down-regulation
CK1_CK1_CK1-A_CSNK1A1_ST	P25054	APC	P48729	CSNK1A1	S905	T899I	899	Missense	distal	-6	no	23.470	22.845	EPSD	COSMIC	20.411	Down-regulation
CK1_CK1_CK1-A_CSNK1A1_ST	P25054	APC	P48729	CSNK1A1	S905	S906F	906	Missense	proximal	1	no	23.470	23.414	EPSD	COSMIC	20.411	Down-regulation
CK1_CK1_CK1-A_CSNK1A1_ST	P25054	APC	P48729	CSNK1A1	S905	L912V	912	Missense	distal	7	no	23.470	23.633	EPSD	COSMIC	20.411	Up-regulation
CK1_CK1_CK1-A_CSNK1A1_ST	P25054	APC	P48729	CSNK1A1	S905	Q901R	901	Missense	distal	-4	no	23.470	21.256	EPSD	COSMIC	20.411	Down-regulation
CK1_CK1_CK1-A_CSNK1A1_ST	P25054	APC	P48729	CSNK1A1	S905	T909P	909	Missense	distal	4	no	23.470	23.469	EPSD	COSMIC	20.411	Down-regulation
CK1_CK1_CK1-A_CSNK1A1_ST	P25054	APC	P48729	CSNK1A1	S905	E911G	911	Missense	distal	6	no	23.470	23.785	EPSD	COSMIC	20.411	Up-regulation
CK1_CK1_CK1-A_CSNK1A1_ST	P25054	APC	P48729	CSNK1A1	S905	D903G	903	Missense	proximal	-2	no	23.470	23.438	EPSD	COSMIC	20.411	Down-regulation
CK1_CK1_CK1-A_CSNK1A1_ST	P25054	APC	P48729	CSNK1A1	S906	T909I	909	Missense	distal	3	no	21.922	23.099	EPSD	COSMIC	20.411	Up-regulation
CK1_CK1_CK1-A_CSNK1A1_ST	P25054	APC	P48729	CSNK1A1	S906	S905G	905	Missense	proximal	-1	no	21.922	22.620	EPSD	COSMIC	20.411	Up-regulation
CK1_CK1_CK1-A_CSNK1A1_ST	P25054	APC	P48729	CSNK1A1	S906	T909A	909	Missense	distal	3	no	21.922	22.125	EPSD	COSMIC	20.411	Up-regulation
CK1_CK1_CK1-A_CSNK1A1_ST	P25054	APC	P48729	CSNK1A1	S906	H913D	913	Missense	distal	7	no	21.922	21.650	EPSD	COSMIC	20.411	Down-regulation
CK1_CK1_CK1-A_CSNK1A1_ST	P25054	APC	P48729	CSNK1A1	S906	S908T	908	Missense	proximal	2	no	21.922	21.130	EPSD	COSMIC	20.411	Down-regulation
CK1_CK1_CK1-A_CSNK1A1_ST	P25054	APC	P48729	CSNK1A1	S906	T899I	899	Missense	distal	-7	no	21.922	22.709	EPSD	COSMIC	20.411	Up-regulation
CK1_CK1_CK1-A_CSNK1A1_ST	P25054	APC	P48729	CSNK1A1	S906	S906F	906	Missense	central	0	yes	21.922	0.000	EPSD	COSMIC	20.411	Loss
CK1_CK1_CK1-A_CSNK1A1_ST	P25054	APC	P48729	CSNK1A1	S906	L912V	912	Missense	distal	6	no	21.922	21.601	EPSD	COSMIC	20.411	Down-regulation
CK1_CK1_CK1-A_CSNK1A1_ST	P25054	APC	P48729	CSNK1A1	S906	Q901R	901	Missense	distal	-5	no	21.922	21.124	EPSD	COSMIC	20.411	Down-regulation
CK1_CK1_CK1-A_CSNK1A1_ST	P25054	APC	P48729	CSNK1A1	S906	T909P	909	Missense	distal	3	no	21.922	20.090	EPSD	COSMIC	20.411	Loss
CK1_CK1_CK1-A_CSNK1A1_ST	P25054	APC	P48729	CSNK1A1	S906	E911G	911	Missense	distal	5	no	21.922	22.266	EPSD	COSMIC	20.411	Up-regulation
CK1_CK1_CK1-A_CSNK1A1_ST	P25054	APC	P48729	CSNK1A1	S906	D903G	903	Missense	distal	-3	no	21.922	19.859	EPSD	COSMIC	20.411	Loss
CK1_CK1_CK1-A_CSNK1A1_ST	P25054	APC	P48729	CSNK1A1	S908	T909I	909	Missense	proximal	1	no	21.006	21.171	EPSD	COSMIC	20.411	Up-regulation
CK1_CK1_CK1-A_CSNK1A1_ST	P25054	APC	P48729	CSNK1A1	S908	C914W	914	Missense	distal	6	no	21.006	20.744	EPSD	COSMIC	20.411	Down-regulation
CK1_CK1_CK1-A_CSNK1A1_ST	P25054	APC	P48729	CSNK1A1	S908	C914Y	914	Missense	distal	6	no	21.006	20.855	EPSD	COSMIC	20.411	Down-regulation
CK1_CK1_CK1-A_CSNK1A1_ST	P25054	APC	P48729	CSNK1A1	S908	S905G	905	Missense	distal	-3	no	21.006	19.315	EPSD	COSMIC	20.411	Loss
CK1_CK1_CK1-A_CSNK1A1_ST	P25054	APC	P48729	CSNK1A1	S908	T909A	909	Missense	proximal	1	no	21.006	20.962	EPSD	COSMIC	20.411	Down-regulation
CK1_CK1_CK1-A_CSNK1A1_ST	P25054	APC	P48729	CSNK1A1	S908	H913D	913	Missense	distal	5	no	21.006	20.708	EPSD	COSMIC	20.411	Down-regulation
CK1_CK1_CK1-A_CSNK1A1_ST	P25054	APC	P48729	CSNK1A1	S908	C914G	914	Missense	distal	6	no	21.006	21.450	EPSD	COSMIC	20.411	Up-regulation
CK1_CK1_CK1-A_CSNK1A1_ST	P25054	APC	P48729	CSNK1A1	S908	S906F	906	Missense	proximal	-2	no	21.006	19.140	EPSD	COSMIC	20.411	Loss
CK1_CK1_CK1-A_CSNK1A1_ST	P25054	APC	P48729	CSNK1A1	S908	V915R	915	Missense	distal	7	no	21.006	20.915	EPSD	COSMIC	20.411	Down-regulation
CK1_CK1_CK1-A_CSNK1A1_ST	P25054	APC	P48729	CSNK1A1	S908	L912V	912	Missense	distal	4	no	21.006	20.882	EPSD	COSMIC	20.411	Down-regulation
CK1_CK1_CK1-A_CSNK1A1_ST	P25054	APC	P48729	CSNK1A1	S908	Q901R	901	Missense	distal	-7	no	21.006	21.320	EPSD	COSMIC	20.411	Up-regulation
CK1_CK1_CK1-A_CSNK1A1_ST	P25054	APC	P48729	CSNK1A1	S908	T909P	909	Missense	proximal	1	no	21.006	21.150	EPSD	COSMIC	20.411	Up-regulation
CK1_CK1_CK1-A_CSNK1A1_ST	P25054	APC	P48729	CSNK1A1	S908	E911G	911	Missense	distal	3	no	21.006	20.872	EPSD	COSMIC	20.411	Down-regulation
CK1_CK1_CK1-A_CSNK1A1_ST	P25054	APC	P48729	CSNK1A1	S908	D903G	903	Missense	distal	-5	no	21.006	21.221	EPSD	COSMIC	20.411	Up-regulation
CK1_CK1_CK1-A_CSNK1A1_ST	P25054	APC	P48729	CSNK1A1	S966	S963I	963	Missense	distal	-3	no	21.829	17.848	EPSD	COSMIC	20.411	Loss
CK1_CK1_CK1-A_CSNK1A1_ST	P25054	APC	P48729	CSNK1A1	S966	D971N	971	Missense	distal	5	no	21.829	22.075	EPSD	COSMIC	20.411	Up-regulation
CK1_CK1_CK1-A_CSNK1A1_ST	P25054	APC	P48729	CSNK1A1	S966	Y973C	973	Missense	distal	7	no	21.829	21.728	EPSD	COSMIC	20.411	Down-regulation
CK1_CK1_CK1-A_CSNK1A1_ST	P25054	APC	P48729	CSNK1A1	S966	S966R	966	Missense	central	0	yes	21.829	0.000	EPSD	COSMIC	20.411	Loss
CK1_CK1_CK1-A_CSNK1A1_ST	P25054	APC	P48729	CSNK1A1	S982	E984K	984	Missense	proximal	2	no	22.598	21.622	EPSD	COSMIC	20.411	Down-regulation
CK1_CK1_CK1-A_CSNK1A1_ST	P25054	APC	P48729	CSNK1A1	S982	P981L	981	Missense	proximal	-1	no	22.598	22.314	EPSD	COSMIC	20.411	Down-regulation
CK1_CK1_CK1-A_CSNK1A1_ST	P25054	APC	P48729	CSNK1A1	S982	M979I	979	Missense	distal	-3	no	22.598	20.873	EPSD	COSMIC	20.411	Down-regulation
CK1_CK1_CK1-A_CSNK1A1_ST	P25054	APC	P48729	CSNK1A1	S982	R976T	976	Missense	distal	-6	no	22.598	22.745	EPSD	COSMIC	20.411	Up-regulation
CK1_CK1_CK1-A_CSNK1A1_ST	P25054	APC	P48729	CSNK1A1	S985	E984K	984	Missense	proximal	-1	no	20.558	18.916	EPSD	COSMIC	20.411	Loss
CK1_CK1_CK1-A_CSNK1A1_ST	P25054	APC	P48729	CSNK1A1	S985	P981L	981	Missense	distal	-4	no	20.558	19.443	EPSD	COSMIC	20.411	Loss
CK1_CK1_CK1-A_CSNK1A1_ST	P25054	APC	P48729	CSNK1A1	S985	M979I	979	Missense	distal	-6	no	20.558	19.690	EPSD	COSMIC	20.411	Loss
CK1_CK1_CK1-A_CSNK1A1_ST	P25054	APC	P48729	CSNK1A1	S987	E984K	984	Missense	distal	-3	no	22.463	18.543	EPSD	COSMIC	20.411	Loss
CK1_CK1_CK1-A_CSNK1A1_ST	P25054	APC	P48729	CSNK1A1	S987	P981L	981	Missense	distal	-6	no	22.463	22.250	EPSD	COSMIC	20.411	Down-regulation
CK1_CK1_CK1-A_CSNK1A1_ST	P25054	APC	P48729	CSNK1A1	S987	K993N	993	Missense	distal	6	no	22.463	22.630	EPSD	COSMIC;GDSC;CCLE	20.411	Up-regulation
CK1_CK1_CK1-A_CSNK1A1_ST	P25054	APC	P48729	CSNK1A1	S992	K993N	993	Missense	proximal	1	no	22.129	22.231	EPSD	COSMIC;GDSC;CCLE	20.411	Up-regulation
CK1_CK1_CK1-A_CSNK1A1_ST	P25054	APC	P48729	CSNK1A1	S992	C995W	995	Missense	distal	3	no	22.129	24.517	EPSD	COSMIC	20.411	Up-regulation
CK1_CK1_CK1-A_CSNK1A1_ST	P25054	APC	P48729	CSNK1A1	S1044	E1047D	1047	Missense	distal	3	no	20.281	20.420	EPSD	COSMIC	20.411	Gain
CK1_CK1_CK1-A_CSNK1A1_ST	P25054	APC	P48729	CSNK1A1	S1104	P1101S	1101	Missense	distal	-3	no	15.658	21.846	EPSD	COSMIC	20.411	Gain
CK1_CK1_CK1-A_CSNK1A1_ST	P25054	APC	P48729	CSNK1A1	S1148	E1145K	1145	Missense	distal	-3	no	22.107	18.187	EPSD	COSMIC	20.411	Loss
CK1_CK1_CK1-A_CSNK1A1_ST	P25054	APC	P48729	CSNK1A1	S1148	E1149D	1149	Missense	proximal	1	no	22.107	21.979	EPSD	COSMIC	20.411	Down-regulation
CK1_CK1_CK1-A_CSNK1A1_ST	P25054	APC	P48729	CSNK1A1	S1238	K1245T	1245	Missense	distal	7	no	23.779	23.834	EPSD	COSMIC	20.411	Up-regulation
CK1_CK1_CK1-A_CSNK1A1_ST	P25054	APC	P48729	CSNK1A1	S1238	H1232Y	1232	Missense	distal	-6	no	23.779	23.837	EPSD	COSMIC	20.411	Up-regulation
CK1_CK1_CK1-A_CSNK1A1_ST	P25054	APC	P48729	CSNK1A1	S1238	H1232R	1232	Missense	distal	-6	no	23.779	24.356	EPSD	COSMIC	20.411	Up-regulation
CK1_CK1_CK1-A_CSNK1A1_ST	P25054	APC	P48729	CSNK1A1	S1279	E1286G	1286	Missense	distal	7	no	22.356	22.503	EPSD	COSMIC	20.411	Up-regulation
CK1_CK1_CK1-A_CSNK1A1_ST	P25054	APC	P48729	CSNK1A1	S1279	E1284D	1284	Missense	distal	5	no	22.356	22.564	EPSD	COSMIC	20.411	Up-regulation
CK1_CK1_CK1-A_CSNK1A1_ST	P25054	APC	P48729	CSNK1A1	S1279	S1275N	1275	Missense	distal	-4	no	22.356	19.613	EPSD	COSMIC	20.411	Loss
CK1_CK1_CK1-A_CSNK1A1_ST	P25054	APC	P48729	CSNK1A1	S1279	E1286Q	1286	Missense	distal	7	no	22.356	22.487	EPSD	COSMIC	20.411	Up-regulation
CK1_CK1_CK1-A_CSNK1A1_ST	P25054	APC	P48729	CSNK1A1	S1279	C1274Y	1274	Missense	distal	-5	no	22.356	21.714	EPSD	COSMIC	20.411	Down-regulation
CK1_CK1_CK1-A_CSNK1A1_ST	P25054	APC	P48729	CSNK1A1	S1279	D1285G	1285	Missense	distal	6	no	22.356	22.445	EPSD	COSMIC	20.411	Up-regulation
CK1_CK1_CK1-A_CSNK1A1_ST	P25054	APC	P48729	CSNK1A1	S1279	R1273K	1273	Missense	distal	-6	no	22.356	21.936	EPSD	COSMIC	20.411	Down-regulation
CK1_CK1_CK1-A_CSNK1A1_ST	P25054	APC	P48729	CSNK1A1	S1279	S1278P	1278	Missense	proximal	-1	no	22.356	22.365	EPSD	COSMIC	20.411	Up-regulation
CK1_CK1_CK1-A_CSNK1A1_ST	P25054	APC	P48729	CSNK1A1	S1279	L1277F	1277	Missense	proximal	-2	no	22.356	23.344	EPSD	COSMIC	20.411	Up-regulation
CK1_CK1_CK1-A_CSNK1A1_ST	P25054	APC	P48729	CSNK1A1	S1279	S1276L	1276	Missense	distal	-3	no	22.356	15.763	EPSD	COSMIC	20.411	Loss
CK1_CK1_CK1-A_CSNK1A1_ST	P25054	APC	P48729	CSNK1A1	S1279	S1276T	1276	Missense	distal	-3	no	22.356	18.592	EPSD	COSMIC	20.411	Loss
CK1_CK1_CK1-A_CSNK1A1_ST	P25054	APC	P48729	CSNK1A1	S1279	E1284K	1284	Missense	distal	5	no	22.356	22.801	EPSD	COSMIC	20.411	Up-regulation
CK1_CK1_CK1-A_CSNK1A1_ST	P25054	APC	P48729	CSNK1A1	S1279	S1275T	1275	Missense	distal	-4	no	22.356	20.722	EPSD	COSMIC;CCLE	20.411	Down-regulation
CK1_CK1_CK1-A_CSNK1A1_ST	P25054	APC	P48729	CSNK1A1	S1343	S1341R	1341	Missense	proximal	-2	no	20.865	19.775	EPSD	COSMIC	20.411	Loss
CK1_CK1_CK1-A_CSNK1A1_ST	P25054	APC	P48729	CSNK1A1	S1343	S1344F	1344	Missense	proximal	1	no	20.865	20.809	EPSD	COSMIC	20.411	Down-regulation
CK1_CK1_CK1-A_CSNK1A1_ST	P25054	APC	P48729	CSNK1A1	S1343	G1339A	1339	Missense	distal	-4	no	20.865	19.100	EPSD	COSMIC	20.411	Loss
CK1_CK1_CK1-A_CSNK1A1_ST	P25054	APC	P48729	CSNK1A1	S1343	G1339D	1339	Missense	distal	-4	no	20.865	21.694	EPSD	COSMIC	20.411	Up-regulation
CK1_CK1_CK1-A_CSNK1A1_ST	P25054	APC	P48729	CSNK1A1	S1343	H1349Y	1349	Missense	distal	6	no	20.865	20.553	EPSD	COSMIC	20.411	Down-regulation
CK1_CK1_CK1-A_CSNK1A1_ST	P25054	APC	P48729	CSNK1A1	S1343	R1348G	1348	Missense	distal	5	no	20.865	20.768	EPSD	COSMIC	20.411	Down-regulation
CK1_CK1_CK1-A_CSNK1A1_ST	P25054	APC	P48729	CSNK1A1	S1343	K1350R	1350	Missense	distal	7	no	20.865	20.968	EPSD	COSMIC	20.411	Up-regulation
CK1_CK1_CK1-A_CSNK1A1_ST	P25054	APC	P48729	CSNK1A1	S1343	S1346P	1346	Missense	distal	3	no	20.865	16.600	EPSD	COSMIC	20.411	Loss
CK1_CK1_CK1-A_CSNK1A1_ST	P25054	APC	P48729	CSNK1A1	S1343	K1350T	1350	Missense	distal	7	no	20.865	20.921	EPSD	COSMIC	20.411	Up-regulation
CK1_CK1_CK1-A_CSNK1A1_ST	P25054	APC	P48729	CSNK1A1	S1343	G1339S	1339	Missense	distal	-4	no	20.865	20.700	EPSD	COSMIC	20.411	Down-regulation
CK1_CK1_CK1-A_CSNK1A1_ST	P25054	APC	P48729	CSNK1A1	S1343	R1336S	1336	Missense	distal	-7	no	20.865	20.464	EPSD	COSMIC	20.411	Down-regulation
CK1_CK1_CK1-A_CSNK1A1_ST	P25054	APC	P48729	CSNK1A1	S1343	R1336I	1336	Missense	distal	-7	no	20.865	20.802	EPSD	COSMIC	20.411	Down-regulation
CK1_CK1_CK1-A_CSNK1A1_ST	P25054	APC	P48729	CSNK1A1	S1344	K1350R	1350	Missense	distal	6	no	20.258	20.449	EPSD	COSMIC	20.411	Gain
CK1_CK1_CK1-A_CSNK1A1_ST	P25054	APC	P48729	CSNK1A1	S1344	K1350T	1350	Missense	distal	6	no	20.258	20.538	EPSD	COSMIC	20.411	Gain
CK1_CK1_CK1-A_CSNK1A1_ST	P25054	APC	P48729	CSNK1A1	S1360	K1363E	1363	Missense	distal	3	no	16.874	21.005	EPSD	COSMIC	20.411	Gain
CK1_CK1_CK1-A_CSNK1A1_ST	P25054	APC	P48729	CSNK1A1	S1371	T1368S	1368	Missense	distal	-3	no	17.563	21.328	EPSD	COSMIC	20.411	Gain
CK1_CK1_CK1-A_CSNK1A1_ST	P25054	APC	P48729	CSNK1A1	S1391	C1387S	1387	Missense	distal	-4	no	18.415	21.114	EPSD	COSMIC	20.411	Gain
CK1_CK1_CK1-A_CSNK1A1_ST	P25054	APC	P48729	CSNK1A1	S1392	V1390I	1390	Missense	proximal	-2	no	21.764	21.941	EPSD	COSMIC	20.411	Up-regulation
CK1_CK1_CK1-A_CSNK1A1_ST	P25054	APC	P48729	CSNK1A1	S1392	R1386S	1386	Missense	distal	-6	no	21.764	22.292	EPSD	COSMIC	20.411	Up-regulation
CK1_CK1_CK1-A_CSNK1A1_ST	P25054	APC	P48729	CSNK1A1	S1392	S1389C	1389	Missense	distal	-3	no	21.764	17.431	EPSD	COSMIC	20.411	Loss
CK1_CK1_CK1-A_CSNK1A1_ST	P25054	APC	P48729	CSNK1A1	S1392	S1385R	1385	Missense	distal	-7	no	21.764	22.165	EPSD	COSMIC	20.411	Up-regulation
CK1_CK1_CK1-A_CSNK1A1_ST	P25054	APC	P48729	CSNK1A1	S1392	C1387S	1387	Missense	distal	-5	no	21.764	23.068	EPSD	COSMIC	20.411	Up-regulation
CK1_CK1_CK1-A_CSNK1A1_ST	P25054	APC	P48729	CSNK1A1	S1392	S1398T	1398	Missense	distal	6	no	21.764	21.660	EPSD	COSMIC	20.411	Down-regulation
CK1_CK1_CK1-A_CSNK1A1_ST	P25054	APC	P48729	CSNK1A1	S1392	D1394N	1394	Missense	proximal	2	no	21.764	20.571	EPSD	COSMIC	20.411	Down-regulation
CK1_CK1_CK1-A_CSNK1A1_ST	P25054	APC	P48729	CSNK1A1	S1392	S1395C	1395	Missense	distal	3	no	21.764	17.721	EPSD	COSMIC	20.411	Loss
CK1_CK1_CK1-A_CSNK1A1_ST	P25054	APC	P48729	CSNK1A1	S1392	V1390D	1390	Missense	proximal	-2	no	21.764	24.004	EPSD	COSMIC	20.411	Up-regulation
CK1_CK1_CK1-A_CSNK1A1_ST	P25054	APC	P48729	CSNK1A1	S1392	S1389Y	1389	Missense	distal	-3	no	21.764	15.788	EPSD	COSMIC	20.411	Loss
CK1_CK1_CK1-A_CSNK1A1_ST	P25054	APC	P48729	CSNK1A1	S1392	L1393P	1393	Missense	proximal	1	no	21.764	21.654	EPSD	COSMIC	20.411	Down-regulation
CK1_CK1_CK1-A_CSNK1A1_ST	P25054	APC	P48729	CSNK1A1	S1392	S1398N	1398	Missense	distal	6	no	21.764	21.547	EPSD	COSMIC	20.411	Down-regulation
CK1_CK1_CK1-A_CSNK1A1_ST	P25054	APC	P48729	CSNK1A1	S1395	V1390I	1390	Missense	distal	-5	no	21.416	23.003	EPSD	COSMIC	20.411	Up-regulation
CK1_CK1_CK1-A_CSNK1A1_ST	P25054	APC	P48729	CSNK1A1	S1395	S1389C	1389	Missense	distal	-6	no	21.416	20.563	EPSD	COSMIC	20.411	Down-regulation
CK1_CK1_CK1-A_CSNK1A1_ST	P25054	APC	P48729	CSNK1A1	S1395	S1398T	1398	Missense	distal	3	no	21.416	18.983	EPSD	COSMIC	20.411	Loss
CK1_CK1_CK1-A_CSNK1A1_ST	P25054	APC	P48729	CSNK1A1	S1395	D1394N	1394	Missense	proximal	-1	no	21.416	20.852	EPSD	COSMIC	20.411	Down-regulation
CK1_CK1_CK1-A_CSNK1A1_ST	P25054	APC	P48729	CSNK1A1	S1395	S1395C	1395	Missense	central	0	yes	21.416	0.000	EPSD	COSMIC	20.411	Loss
CK1_CK1_CK1-A_CSNK1A1_ST	P25054	APC	P48729	CSNK1A1	S1395	V1390D	1390	Missense	distal	-5	no	21.416	23.254	EPSD	COSMIC	20.411	Up-regulation
CK1_CK1_CK1-A_CSNK1A1_ST	P25054	APC	P48729	CSNK1A1	S1395	S1389Y	1389	Missense	distal	-6	no	21.416	20.368	EPSD	COSMIC	20.411	Loss
CK1_CK1_CK1-A_CSNK1A1_ST	P25054	APC	P48729	CSNK1A1	S1395	L1393P	1393	Missense	proximal	-2	no	21.416	22.400	EPSD	COSMIC	20.411	Up-regulation
CK1_CK1_CK1-A_CSNK1A1_ST	P25054	APC	P48729	CSNK1A1	S1395	S1398N	1398	Missense	distal	3	no	21.416	18.938	EPSD	COSMIC	20.411	Loss
CK1_CK1_CK1-A_CSNK1A1_ST	P25054	APC	P48729	CSNK1A1	S1398	D1394N	1394	Missense	distal	-4	no	25.131	21.393	EPSD	COSMIC	20.411	Down-regulation
CK1_CK1_CK1-A_CSNK1A1_ST	P25054	APC	P48729	CSNK1A1	S1398	S1395C	1395	Missense	distal	-3	no	25.131	20.799	EPSD	COSMIC	20.411	Down-regulation
CK1_CK1_CK1-A_CSNK1A1_ST	P25054	APC	P48729	CSNK1A1	S1398	S1403N	1403	Missense	distal	5	no	25.131	25.552	EPSD	COSMIC	20.411	Up-regulation
CK1_CK1_CK1-A_CSNK1A1_ST	P25054	APC	P48729	CSNK1A1	S1398	V1405I	1405	Missense	distal	7	no	25.131	24.842	EPSD	COSMIC	20.411	Down-regulation
CK1_CK1_CK1-A_CSNK1A1_ST	P25054	APC	P48729	CSNK1A1	S1398	L1393P	1393	Missense	distal	-5	no	25.131	25.327	EPSD	COSMIC	20.411	Up-regulation
CK1_CK1_CK1-A_CSNK1A1_ST	P25054	APC	P48729	CSNK1A1	S1398	S1398N	1398	Missense	central	0	yes	25.131	0.000	EPSD	COSMIC	20.411	Loss
CK1_CK1_CK1-A_CSNK1A1_ST	P25054	APC	P48729	CSNK1A1	S1501	S1501A	1501	Missense	central	0	yes	26.380	0.000	EPSD	COSMIC	20.411	Loss
CK1_CK1_CK1-A_CSNK1A1_ST	P25054	APC	P48729	CSNK1A1	S1501	P1497S	1497	Missense	distal	-4	no	26.380	29.072	EPSD	COSMIC	20.411	Up-regulation
CK1_CK1_CK1-A_CSNK1A1_ST	P25054	APC	P48729	CSNK1A1	S1501	G1499R	1499	Missense	proximal	-2	no	26.380	25.439	EPSD	COSMIC	20.411	Down-regulation
CK1_CK1_CK1-A_CSNK1A1_ST	P25054	APC	P48729	CSNK1A1	S1501	E1494K	1494	Missense	distal	-7	no	26.380	26.618	EPSD	COSMIC	20.411	Up-regulation
CK1_CK1_CK1-A_CSNK1A1_ST	P25054	APC	P48729	CSNK1A1	S1501	S1495G	1495	Missense	distal	-6	no	26.380	26.521	EPSD	COSMIC	20.411	Up-regulation
CK1_CK1_CK1-A_CSNK1A1_ST	P25054	APC	P48729	CSNK1A1	S1501	D1498N	1498	Missense	distal	-3	no	26.380	21.100	EPSD	COSMIC	20.411	Down-regulation
CK1_CK1_CK1-A_CSNK1A1_ST	P25054	APC	P48729	CSNK1A1	S1501	S1495I	1495	Missense	distal	-6	no	26.380	25.374	EPSD	COSMIC	20.411	Down-regulation
CK1_CK1_CK1-A_CSNK1A1_ST	P25054	APC	P48729	CSNK1A1	S1501	S1504F	1504	Missense	distal	3	no	26.380	23.919	EPSD	COSMIC	20.411	Down-regulation
CK1_CK1_CK1-A_CSNK1A1_ST	P25054	APC	P48729	CSNK1A1	S1501	A1508V	1508	Missense	distal	7	no	26.380	26.499	EPSD	COSMIC	20.411	Up-regulation
CK1_CK1_CK1-A_CSNK1A1_ST	P25054	APC	P48729	CSNK1A1	S1501	P1497L	1497	Missense	distal	-4	no	26.380	25.265	EPSD	COSMIC	20.411	Down-regulation
CK1_CK1_CK1-A_CSNK1A1_ST	P25054	APC	P48729	CSNK1A1	S1501	S1503L	1503	Missense	proximal	2	no	26.380	25.395	EPSD	COSMIC	20.411	Down-regulation
CK1_CK1_CK1-A_CSNK1A1_ST	P25054	APC	P48729	CSNK1A1	S1501	S1501F	1501	Missense	central	0	yes	26.380	0.000	EPSD	COSMIC	20.411	Loss
CK1_CK1_CK1-A_CSNK1A1_ST	P25054	APC	P48729	CSNK1A1	S1504	S1501A	1501	Missense	distal	-3	no	24.414	19.958	EPSD;PhosphoSitePlus	COSMIC	20.411	Loss
CK1_CK1_CK1-A_CSNK1A1_ST	P25054	APC	P48729	CSNK1A1	S1504	P1497S	1497	Missense	distal	-7	no	24.414	25.080	EPSD;PhosphoSitePlus	COSMIC	20.411	Up-regulation
CK1_CK1_CK1-A_CSNK1A1_ST	P25054	APC	P48729	CSNK1A1	S1504	G1499R	1499	Missense	distal	-5	no	24.414	23.250	EPSD;PhosphoSitePlus	COSMIC	20.411	Down-regulation
CK1_CK1_CK1-A_CSNK1A1_ST	P25054	APC	P48729	CSNK1A1	S1504	D1498N	1498	Missense	distal	-6	no	24.414	23.134	EPSD;PhosphoSitePlus	COSMIC	20.411	Down-regulation
CK1_CK1_CK1-A_CSNK1A1_ST	P25054	APC	P48729	CSNK1A1	S1504	S1504F	1504	Missense	central	0	yes	24.414	0.000	EPSD;PhosphoSitePlus	COSMIC	20.411	Loss
CK1_CK1_CK1-A_CSNK1A1_ST	P25054	APC	P48729	CSNK1A1	S1504	A1508V	1508	Missense	distal	4	no	24.414	24.344	EPSD;PhosphoSitePlus	COSMIC	20.411	Down-regulation
CK1_CK1_CK1-A_CSNK1A1_ST	P25054	APC	P48729	CSNK1A1	S1504	P1497L	1497	Missense	distal	-7	no	24.414	24.399	EPSD;PhosphoSitePlus	COSMIC	20.411	Down-regulation
CK1_CK1_CK1-A_CSNK1A1_ST	P25054	APC	P48729	CSNK1A1	S1504	S1503L	1503	Missense	proximal	-1	no	24.414	24.139	EPSD;PhosphoSitePlus	COSMIC	20.411	Down-regulation
CK1_CK1_CK1-A_CSNK1A1_ST	P25054	APC	P48729	CSNK1A1	S1504	S1501F	1501	Missense	distal	-3	no	24.414	18.762	EPSD;PhosphoSitePlus	COSMIC	20.411	Loss
CK1_CK1_CK1-A_CSNK1A1_ST	P25054	APC	P48729	CSNK1A1	S1505	S1501A	1501	Missense	distal	-4	no	20.965	19.365	EPSD;PhosphoSitePlus	COSMIC	20.411	Loss
CK1_CK1_CK1-A_CSNK1A1_ST	P25054	APC	P48729	CSNK1A1	S1505	G1499R	1499	Missense	distal	-6	no	20.965	20.296	EPSD;PhosphoSitePlus	COSMIC	20.411	Loss
CK1_CK1_CK1-A_CSNK1A1_ST	P25054	APC	P48729	CSNK1A1	S1505	D1512N	1512	Missense	distal	7	no	20.965	21.049	EPSD;PhosphoSitePlus	COSMIC	20.411	Up-regulation
CK1_CK1_CK1-A_CSNK1A1_ST	P25054	APC	P48729	CSNK1A1	S1505	D1498N	1498	Missense	distal	-7	no	20.965	20.908	EPSD;PhosphoSitePlus	COSMIC	20.411	Down-regulation
CK1_CK1_CK1-A_CSNK1A1_ST	P25054	APC	P48729	CSNK1A1	S1505	S1504F	1504	Missense	proximal	-1	no	20.965	20.263	EPSD;PhosphoSitePlus	COSMIC	20.411	Loss
CK1_CK1_CK1-A_CSNK1A1_ST	P25054	APC	P48729	CSNK1A1	S1505	A1508V	1508	Missense	distal	3	no	20.965	20.610	EPSD;PhosphoSitePlus	COSMIC	20.411	Down-regulation
CK1_CK1_CK1-A_CSNK1A1_ST	P25054	APC	P48729	CSNK1A1	S1505	S1503L	1503	Missense	proximal	-2	no	20.965	18.111	EPSD;PhosphoSitePlus	COSMIC	20.411	Loss
CK1_CK1_CK1-A_CSNK1A1_ST	P25054	APC	P48729	CSNK1A1	S1505	S1501F	1501	Missense	distal	-4	no	20.965	19.315	EPSD;PhosphoSitePlus	COSMIC	20.411	Loss
CK1_CK1_CK1-A_CSNK1A1_ST	P25054	APC	P48729	CSNK1A1	S1505	D1512V	1512	Missense	distal	7	no	20.965	21.202	EPSD;PhosphoSitePlus	COSMIC	20.411	Up-regulation
CK1_CK1_CK1-A_CSNK1A1_ST	P25054	APC	P48729	CSNK1A1	S1507	S1501A	1501	Missense	distal	-6	no	26.279	25.371	PhosphoSitePlus;EPSD	COSMIC	20.411	Down-regulation
CK1_CK1_CK1-A_CSNK1A1_ST	P25054	APC	P48729	CSNK1A1	S1507	P1514L	1514	Missense	distal	7	no	26.279	26.127	PhosphoSitePlus;EPSD	COSMIC	20.411	Down-regulation
CK1_CK1_CK1-A_CSNK1A1_ST	P25054	APC	P48729	CSNK1A1	S1507	D1512N	1512	Missense	distal	5	no	26.279	26.525	PhosphoSitePlus;EPSD	COSMIC	20.411	Up-regulation
CK1_CK1_CK1-A_CSNK1A1_ST	P25054	APC	P48729	CSNK1A1	S1507	S1504F	1504	Missense	distal	-3	no	26.279	20.627	PhosphoSitePlus;EPSD	COSMIC	20.411	Down-regulation
CK1_CK1_CK1-A_CSNK1A1_ST	P25054	APC	P48729	CSNK1A1	S1507	A1508V	1508	Missense	proximal	1	no	26.279	26.302	PhosphoSitePlus;EPSD	COSMIC	20.411	Up-regulation
CK1_CK1_CK1-A_CSNK1A1_ST	P25054	APC	P48729	CSNK1A1	S1507	P1514S	1514	Missense	distal	7	no	26.279	26.091	PhosphoSitePlus;EPSD	COSMIC	20.411	Down-regulation
CK1_CK1_CK1-A_CSNK1A1_ST	P25054	APC	P48729	CSNK1A1	S1507	S1503L	1503	Missense	distal	-4	no	26.279	22.472	PhosphoSitePlus;EPSD	COSMIC	20.411	Down-regulation
CK1_CK1_CK1-A_CSNK1A1_ST	P25054	APC	P48729	CSNK1A1	S1507	S1501F	1501	Missense	distal	-6	no	26.279	25.065	PhosphoSitePlus;EPSD	COSMIC	20.411	Down-regulation
CK1_CK1_CK1-A_CSNK1A1_ST	P25054	APC	P48729	CSNK1A1	S1507	D1512V	1512	Missense	distal	5	no	26.279	26.455	PhosphoSitePlus;EPSD	COSMIC	20.411	Up-regulation
CK1_CK1_CK1-A_CSNK1A1_ST	P25054	APC	P48729	CSNK1A1	S1510	P1514L	1514	Missense	distal	4	no	23.496	23.563	EPSD;PhosphoSitePlus	COSMIC	20.411	Up-regulation
CK1_CK1_CK1-A_CSNK1A1_ST	P25054	APC	P48729	CSNK1A1	S1510	D1512N	1512	Missense	proximal	2	no	23.496	22.302	EPSD;PhosphoSitePlus	COSMIC	20.411	Down-regulation
CK1_CK1_CK1-A_CSNK1A1_ST	P25054	APC	P48729	CSNK1A1	S1510	S1504F	1504	Missense	distal	-6	no	23.496	22.282	EPSD;PhosphoSitePlus	COSMIC	20.411	Down-regulation
CK1_CK1_CK1-A_CSNK1A1_ST	P25054	APC	P48729	CSNK1A1	S1510	A1508V	1508	Missense	proximal	-2	no	23.496	22.098	EPSD;PhosphoSitePlus	COSMIC	20.411	Down-regulation
CK1_CK1_CK1-A_CSNK1A1_ST	P25054	APC	P48729	CSNK1A1	S1510	P1514S	1514	Missense	distal	4	no	23.496	23.533	EPSD;PhosphoSitePlus	COSMIC	20.411	Up-regulation
CK1_CK1_CK1-A_CSNK1A1_ST	P25054	APC	P48729	CSNK1A1	S1510	I1516V	1516	Missense	distal	6	no	23.496	23.038	EPSD;PhosphoSitePlus	COSMIC	20.411	Down-regulation
CK1_CK1_CK1-A_CSNK1A1_ST	P25054	APC	P48729	CSNK1A1	S1510	S1503L	1503	Missense	distal	-7	no	23.496	22.815	EPSD;PhosphoSitePlus	COSMIC	20.411	Down-regulation
CK1_CK1_CK1-A_CSNK1A1_ST	P25054	APC	P48729	CSNK1A1	S1510	F1515L	1515	Missense	distal	5	no	23.496	23.301	EPSD;PhosphoSitePlus	COSMIC	20.411	Down-regulation
CK1_CK1_CK1-A_CSNK1A1_ST	P25054	APC	P48729	CSNK1A1	S1510	D1512V	1512	Missense	proximal	2	no	23.496	22.081	EPSD;PhosphoSitePlus	COSMIC	20.411	Down-regulation
CK1_CK1_CK1-A_CSNK1A1_ST	P25054	APC	P48729	CSNK1A1	S1656	S1652P	1652	Missense	distal	-4	no	20.731	18.039	EPSD	COSMIC	20.411	Loss
CK1_CK1_CK1-A_CSNK1A1_ST	P25054	APC	P48729	CSNK1A1	S1656	S1656F	1656	Missense	central	0	yes	20.731	0.000	EPSD	COSMIC	20.411	Loss
CK1_CK1_CK1-A_CSNK1A1_ST	P25054	APC	P48729	CSNK1A1	S1656	L1660P	1660	Missense	distal	4	no	20.731	20.664	EPSD	COSMIC	20.411	Down-regulation
CK1_CK1_CK1-A_CSNK1A1_ST	P25054	APC	P48729	CSNK1A1	S1656	E1663K	1663	Missense	distal	7	no	20.731	20.860	EPSD	COSMIC	20.411	Up-regulation
CK1_CK1_CK1-A_CSNK1A1_ST	P25054	APC	P48729	CSNK1A1	S1656	S1656Y	1656	Missense	central	0	yes	20.731	0.000	EPSD	COSMIC;GDSC;CCLE	20.411	Loss
CK1_CK1_CK1-A_CSNK1A1_ST	P25054	APC	P48729	CSNK1A1	S1656	L1657R	1657	Missense	proximal	1	no	20.731	20.414	EPSD	COSMIC	20.411	Down-regulation
CK1_CK1_CK1-A_CSNK1A1_ST	P25054	APC	P48729	CSNK1A1	S1656	S1658R	1658	Missense	proximal	2	no	20.731	20.124	EPSD	COSMIC	20.411	Loss
CK1_CK1_CK1-A_CSNK1A1_ST	P25054	APC	P48729	CSNK1A1	S1863	R1858Q	1858	Missense	distal	-5	no	19.650	20.447	EPSD	COSMIC	20.411	Gain
CK1_CK1_CK1-A_CSNK1A1_ST	P25054	APC	P48729	CSNK1A1	S1864	R1858Q	1858	Missense	distal	-6	no	20.267	20.455	EPSD	COSMIC	20.411	Gain
CK1_CK1_CK1-A_CSNK1A1_ST	P25054	APC	P48729	CSNK1A1	S1864	L1862F	1862	Missense	proximal	-2	no	20.267	21.254	EPSD	COSMIC	20.411	Gain
CK1_CK1_CK1-A_CSNK1A1_ST	P25054	APC	P48729	CSNK1A1	S2034	L2027P	2027	Missense	distal	-7	no	22.264	22.278	EPSD	COSMIC	20.411	Up-regulation
CK1_CK1_CK1-A_CSNK1A1_ST	P25054	APC	P48729	CSNK1A1	S2034	L2030I	2030	Missense	distal	-4	no	22.264	23.872	EPSD	COSMIC	20.411	Up-regulation
CK1_CK1_CK1-A_CSNK1A1_ST	P25054	APC	P48729	CSNK1A1	S2034	D2037H	2037	Missense	distal	3	no	22.264	17.716	EPSD	COSMIC	20.411	Loss
CK1_CK1_CK1-A_CSNK1A1_ST	P25054	APC	P48729	CSNK1A1	S2064	N2060D	2060	Missense	distal	-4	no	16.729	20.467	EPSD	COSMIC	20.411	Gain
CK1_CK1_CK1-A_CSNK1A1_ST	P25054	APC	P48729	CSNK1A1	S2088	I2083M	2083	Missense	distal	-5	no	23.316	24.074	EPSD	COSMIC	20.411	Up-regulation
CK1_CK1_CK1-A_CSNK1A1_ST	P25054	APC	P48729	CSNK1A1	S2088	P2094L	2094	Missense	distal	6	no	23.316	23.402	EPSD	COSMIC	20.411	Up-regulation
CK1_CK1_CK1-A_CSNK1A1_ST	P25054	APC	P48729	CSNK1A1	S2088	I2083T	2083	Missense	distal	-5	no	23.316	22.857	EPSD	COSMIC;CCLE	20.411	Down-regulation
CK1_CK1_CK1-A_CSNK1A1_ST	P25054	APC	P48729	CSNK1A1	S2088	S2093Y	2093	Missense	distal	5	no	23.316	23.743	EPSD	COSMIC	20.411	Up-regulation
CK1_CK1_CK1-A_CSNK1A1_ST	P25054	APC	P48729	CSNK1A1	S2088	D2082G	2082	Missense	distal	-6	no	23.316	23.191	EPSD	COSMIC	20.411	Down-regulation
CK1_CK1_CK1-A_CSNK1A1_ST	P25054	APC	P48729	CSNK1A1	S2088	Q2084H	2084	Missense	distal	-4	no	23.316	19.061	EPSD	COSMIC	20.411	Loss
CK1_CK1_CK1-A_CSNK1A1_ST	P25054	APC	P48729	CSNK1A1	S2088	L2092I	2092	Missense	distal	4	no	23.316	23.307	EPSD	COSMIC	20.411	Down-regulation
CK1_CK1_CK1-A_CSNK1A1_ST	P25054	APC	P48729	CSNK1A1	S2129	R2126G	2126	Missense	distal	-3	no	20.212	22.746	EPSD	COSMIC	20.411	Gain
CK1_CK1_CK1-A_CSNK1A1_ST	P25054	APC	P48729	CSNK1A1	S2129	S2134C	2134	Missense	distal	5	no	20.212	20.535	EPSD	COSMIC;GDSC;CCLE	20.411	Gain
CK1_CK1_CK1-A_CSNK1A1_ST	P25054	APC	P48729	CSNK1A1	S2129	R2126S	2126	Missense	distal	-3	no	20.212	24.437	EPSD	COSMIC	20.411	Gain
CK1_CK1_CK1-A_CSNK1A1_ST	P25054	APC	P48729	CSNK1A1	S2130	S2125F	2125	Missense	distal	-5	no	20.621	18.721	EPSD	COSMIC	20.411	Loss
CK1_CK1_CK1-A_CSNK1A1_ST	P25054	APC	P48729	CSNK1A1	S2130	S2129L	2129	Missense	proximal	-1	no	20.621	20.346	EPSD	COSMIC;GDSC	20.411	Loss
CK1_CK1_CK1-A_CSNK1A1_ST	P25054	APC	P48729	CSNK1A1	S2130	R2126G	2126	Missense	distal	-4	no	20.621	22.820	EPSD	COSMIC	20.411	Up-regulation
CK1_CK1_CK1-A_CSNK1A1_ST	P25054	APC	P48729	CSNK1A1	S2130	D2131Y	2131	Missense	proximal	1	no	20.621	20.378	EPSD	COSMIC	20.411	Loss
CK1_CK1_CK1-A_CSNK1A1_ST	P25054	APC	P48729	CSNK1A1	S2130	S2134C	2134	Missense	distal	4	no	20.621	20.502	EPSD	COSMIC;GDSC;CCLE	20.411	Down-regulation
CK1_CK1_CK1-A_CSNK1A1_ST	P25054	APC	P48729	CSNK1A1	S2130	S2137F	2137	Missense	distal	7	no	20.621	20.809	EPSD	COSMIC	20.411	Up-regulation
CK1_CK1_CK1-A_CSNK1A1_ST	P25054	APC	P48729	CSNK1A1	S2130	L2136F	2136	Missense	distal	6	no	20.621	20.184	EPSD	COSMIC	20.411	Loss
CK1_CK1_CK1-A_CSNK1A1_ST	P25054	APC	P48729	CSNK1A1	S2130	A2128V	2128	Missense	proximal	-2	no	20.621	19.224	EPSD	COSMIC	20.411	Loss
CK1_CK1_CK1-A_CSNK1A1_ST	P25054	APC	P48729	CSNK1A1	S2130	R2126S	2126	Missense	distal	-4	no	20.621	22.655	EPSD	COSMIC	20.411	Up-regulation
CK1_CK1_CK1-A_CSNK1A1_ST	P25054	APC	P48729	CSNK1A1	S2132	S2125F	2125	Missense	distal	-7	no	21.109	20.691	EPSD	COSMIC	20.411	Down-regulation
CK1_CK1_CK1-A_CSNK1A1_ST	P25054	APC	P48729	CSNK1A1	S2132	S2129L	2129	Missense	distal	-3	no	21.109	14.515	EPSD	COSMIC;GDSC	20.411	Loss
CK1_CK1_CK1-A_CSNK1A1_ST	P25054	APC	P48729	CSNK1A1	S2132	R2126G	2126	Missense	distal	-6	no	21.109	21.777	EPSD	COSMIC	20.411	Up-regulation
CK1_CK1_CK1-A_CSNK1A1_ST	P25054	APC	P48729	CSNK1A1	S2132	D2131Y	2131	Missense	proximal	-1	no	21.109	19.798	EPSD	COSMIC	20.411	Loss
CK1_CK1_CK1-A_CSNK1A1_ST	P25054	APC	P48729	CSNK1A1	S2132	S2134C	2134	Missense	proximal	2	no	21.109	20.124	EPSD	COSMIC;GDSC;CCLE	20.411	Loss
CK1_CK1_CK1-A_CSNK1A1_ST	P25054	APC	P48729	CSNK1A1	S2132	S2137F	2137	Missense	distal	5	no	21.109	21.616	EPSD	COSMIC	20.411	Up-regulation
CK1_CK1_CK1-A_CSNK1A1_ST	P25054	APC	P48729	CSNK1A1	S2132	L2136F	2136	Missense	distal	4	no	21.109	20.992	EPSD	COSMIC	20.411	Down-regulation
CK1_CK1_CK1-A_CSNK1A1_ST	P25054	APC	P48729	CSNK1A1	S2132	A2128V	2128	Missense	distal	-4	no	21.109	19.925	EPSD	COSMIC	20.411	Loss
CK1_CK1_CK1-A_CSNK1A1_ST	P25054	APC	P48729	CSNK1A1	S2132	R2126S	2126	Missense	distal	-6	no	21.109	21.637	EPSD	COSMIC	20.411	Up-regulation
CK1_CK1_CK1-A_CSNK1A1_ST	P25054	APC	P48729	CSNK1A1	S2134	S2129L	2129	Missense	distal	-5	no	26.075	25.446	EPSD	COSMIC;GDSC	20.411	Down-regulation
CK1_CK1_CK1-A_CSNK1A1_ST	P25054	APC	P48729	CSNK1A1	S2134	D2131Y	2131	Missense	distal	-3	no	26.075	19.728	EPSD	COSMIC	20.411	Loss
CK1_CK1_CK1-A_CSNK1A1_ST	P25054	APC	P48729	CSNK1A1	S2134	S2134C	2134	Missense	central	0	yes	26.075	0.000	EPSD	COSMIC;GDSC;CCLE	20.411	Loss
CK1_CK1_CK1-A_CSNK1A1_ST	P25054	APC	P48729	CSNK1A1	S2134	S2137F	2137	Missense	distal	3	no	26.075	23.614	EPSD	COSMIC	20.411	Down-regulation
CK1_CK1_CK1-A_CSNK1A1_ST	P25054	APC	P48729	CSNK1A1	S2134	L2136F	2136	Missense	proximal	2	no	26.075	26.038	EPSD	COSMIC	20.411	Down-regulation
CK1_CK1_CK1-A_CSNK1A1_ST	P25054	APC	P48729	CSNK1A1	S2134	A2128V	2128	Missense	distal	-6	no	26.075	25.817	EPSD	COSMIC	20.411	Down-regulation
CK1_CK1_CK1-A_CSNK1A1_ST	P25054	APC	P48729	CSNK1A1	S2134	G2141R	2141	Missense	distal	7	no	26.075	26.160	EPSD	COSMIC	20.411	Up-regulation
CK1_CK1_CK1-A_CSNK1A1_ST	P25054	APC	P48729	CSNK1A1	S2137	D2131Y	2131	Missense	distal	-6	no	22.652	21.339	EPSD	COSMIC	20.411	Down-regulation
CK1_CK1_CK1-A_CSNK1A1_ST	P25054	APC	P48729	CSNK1A1	S2137	S2134C	2134	Missense	distal	-3	no	22.652	18.320	EPSD	COSMIC;GDSC;CCLE	20.411	Loss
CK1_CK1_CK1-A_CSNK1A1_ST	P25054	APC	P48729	CSNK1A1	S2137	S2137F	2137	Missense	central	0	yes	22.652	0.000	EPSD	COSMIC	20.411	Loss
CK1_CK1_CK1-A_CSNK1A1_ST	P25054	APC	P48729	CSNK1A1	S2137	L2136F	2136	Missense	proximal	-1	no	22.652	22.225	EPSD	COSMIC	20.411	Down-regulation
CK1_CK1_CK1-A_CSNK1A1_ST	P25054	APC	P48729	CSNK1A1	S2140	L2136F	2136	Missense	distal	-4	no	19.971	22.129	EPSD	COSMIC	20.411	Gain
CK1_CK1_CK1-A_CSNK1A1_ST	P25054	APC	P48729	CSNK1A1	S2143	H2149N	2149	Missense	distal	6	no	21.084	21.131	EPSD	COSMIC	20.411	Up-regulation
CK1_CK1_CK1-A_CSNK1A1_ST	P25054	APC	P48729	CSNK1A1	S2143	P2147A	2147	Missense	distal	4	no	21.084	21.097	EPSD	COSMIC	20.411	Up-regulation
CK1_CK1_CK1-A_CSNK1A1_ST	P25054	APC	P48729	CSNK1A1	S2143	S2137F	2137	Missense	distal	-6	no	21.084	19.871	EPSD	COSMIC	20.411	Loss
CK1_CK1_CK1-A_CSNK1A1_ST	P25054	APC	P48729	CSNK1A1	S2143	L2136F	2136	Missense	distal	-7	no	21.084	21.347	EPSD	COSMIC	20.411	Up-regulation
CK1_CK1_CK1-A_CSNK1A1_ST	P25054	APC	P48729	CSNK1A1	S2143	G2145E	2145	Missense	proximal	2	no	21.084	20.689	EPSD	COSMIC	20.411	Down-regulation
CK1_CK1_CK1-A_CSNK1A1_ST	P25054	APC	P48729	CSNK1A1	S2143	G2141R	2141	Missense	proximal	-2	no	21.084	20.143	EPSD	COSMIC	20.411	Loss
CK1_CK1_CK1-A_CSNK1A1_ST	P25054	APC	P48729	CSNK1A1	S2247	V2246I	2246	Missense	proximal	-1	no	19.629	21.120	EPSD	COSMIC	20.411	Gain
CK1_CK1_CK1-A_CSNK1A1_ST	P25054	APC	P48729	CSNK1A1	S2300	K2297E	2297	Missense	distal	-3	no	19.632	23.552	EPSD	COSMIC	20.411	Gain
CK1_CK1_CK1-A_CSNK1A1_ST	P25054	APC	P48729	CSNK1A1	S2307	G2303R	2303	Missense	distal	-4	no	23.911	21.712	EPSD	COSMIC	20.411	Down-regulation
CK1_CK1_CK1-A_CSNK1A1_ST	P25054	APC	P48729	CSNK1A1	S2307	S2302L	2302	Missense	distal	-5	no	23.911	23.282	EPSD	COSMIC	20.411	Down-regulation
CK1_CK1_CK1-A_CSNK1A1_ST	P25054	APC	P48729	CSNK1A1	S2307	A2313T	2313	Missense	distal	6	no	23.911	24.165	EPSD	COSMIC	20.411	Up-regulation
CK1_CK1_CK1-A_CSNK1A1_ST	P25054	APC	P48729	CSNK1A1	S2307	P2309L	2309	Missense	proximal	2	no	23.911	23.941	EPSD	COSMIC	20.411	Up-regulation
CK1_CK1_CK1-A_CSNK1A1_ST	P25054	APC	P48729	CSNK1A1	S2307	R2311T	2311	Missense	distal	4	no	23.911	23.847	EPSD	COSMIC	20.411	Down-regulation
CK1_CK1_CK1-A_CSNK1A1_ST	P25054	APC	P48729	CSNK1A1	S2310	S2307T	2307	Missense	distal	-3	no	22.245	18.481	EPSD	COSMIC	20.411	Loss
CK1_CK1_CK1-A_CSNK1A1_ST	P25054	APC	P48729	CSNK1A1	S2310	G2303R	2303	Missense	distal	-7	no	22.245	21.594	EPSD	COSMIC	20.411	Down-regulation
CK1_CK1_CK1-A_CSNK1A1_ST	P25054	APC	P48729	CSNK1A1	S2310	A2313T	2313	Missense	distal	3	no	22.245	22.042	EPSD	COSMIC	20.411	Down-regulation
CK1_CK1_CK1-A_CSNK1A1_ST	P25054	APC	P48729	CSNK1A1	S2310	P2309L	2309	Missense	proximal	-1	no	22.245	21.961	EPSD	COSMIC	20.411	Down-regulation
CK1_CK1_CK1-A_CSNK1A1_ST	P25054	APC	P48729	CSNK1A1	S2310	R2311T	2311	Missense	proximal	1	no	22.245	22.307	EPSD	COSMIC	20.411	Up-regulation
CK1_CK1_CK1-A_CSNK1A1_ST	P25054	APC	P48729	CSNK1A1	S2310	P2316L	2316	Missense	distal	6	no	22.245	22.331	EPSD	COSMIC	20.411	Up-regulation
CK1_CK1_CK1-A_CSNK1A1_ST	P25054	APC	P48729	CSNK1A1	S2424	S2421T	2421	Missense	distal	-3	no	22.868	19.103	EPSD	COSMIC	20.411	Loss
CK1_CK1_CK1-A_CSNK1A1_ST	P25054	APC	P48729	CSNK1A1	S2424	D2430N	2430	Missense	distal	6	no	22.868	22.721	EPSD	COSMIC	20.411	Down-regulation
CK1_CK1_CK1-A_CSNK1A1_ST	P25054	APC	P48729	CSNK1A1	S2424	S2417Y	2417	Missense	distal	-7	no	22.868	21.399	EPSD	COSMIC	20.411	Down-regulation
CK1_CK1_CK1-A_CSNK1A1_ST	P25054	APC	P48729	CSNK1A1	S2424	E2428K	2428	Missense	distal	4	no	22.868	22.678	EPSD	COSMIC	20.411	Down-regulation
CK1_CK1_CK1-A_CSNK1A1_ST	P25054	APC	P48729	CSNK1A1	S2424	T2422S	2422	Missense	proximal	-2	no	22.868	24.000	EPSD	COSMIC	20.411	Up-regulation
CK1_CK1_CK1-A_CSNK1A1_ST	P25054	APC	P48729	CSNK1A1	S2425	S2421T	2421	Missense	distal	-4	no	20.707	19.072	EPSD	COSMIC	20.411	Loss
CK1_CK1_CK1-A_CSNK1A1_ST	P25054	APC	P48729	CSNK1A1	S2425	D2430N	2430	Missense	distal	5	no	20.707	20.953	EPSD	COSMIC	20.411	Up-regulation
CK1_CK1_CK1-A_CSNK1A1_ST	P25054	APC	P48729	CSNK1A1	S2425	E2428K	2428	Missense	distal	3	no	20.707	16.576	EPSD	COSMIC	20.411	Loss
CK1_CK1_CK1-A_CSNK1A1_ST	P25054	APC	P48729	CSNK1A1	S2425	T2422S	2422	Missense	distal	-3	no	20.707	24.471	EPSD	COSMIC	20.411	Up-regulation
CK1_CK1_CK1-A_CSNK1A1_ST	P25054	APC	P48729	CSNK1A1	S2427	S2421T	2421	Missense	distal	-6	no	22.212	21.830	EPSD	COSMIC	20.411	Down-regulation
CK1_CK1_CK1-A_CSNK1A1_ST	P25054	APC	P48729	CSNK1A1	S2427	D2430N	2430	Missense	distal	3	no	22.212	19.012	EPSD	COSMIC	20.411	Loss
CK1_CK1_CK1-A_CSNK1A1_ST	P25054	APC	P48729	CSNK1A1	S2427	E2428K	2428	Missense	proximal	1	no	22.212	21.752	EPSD	COSMIC	20.411	Down-regulation
CK1_CK1_CK1-A_CSNK1A1_ST	P25054	APC	P48729	CSNK1A1	S2427	T2422S	2422	Missense	distal	-5	no	22.212	22.843	EPSD	COSMIC	20.411	Up-regulation
CK1_CK1_CK1-A_CSNK1A1_ST	P25054	APC	P48729	CSNK1A1	S2427	R2434I	2434	Missense	distal	7	no	22.212	22.014	EPSD	COSMIC	20.411	Down-regulation
CK1_CK1_CK1-A_CSNK1A1_ST	P25054	APC	P48729	CSNK1A1	S2429	D2430N	2430	Missense	proximal	1	no	21.026	20.796	EPSD	COSMIC	20.411	Down-regulation
CK1_CK1_CK1-A_CSNK1A1_ST	P25054	APC	P48729	CSNK1A1	S2429	E2428K	2428	Missense	proximal	-1	no	21.026	19.385	EPSD	COSMIC	20.411	Loss
CK1_CK1_CK1-A_CSNK1A1_ST	P25054	APC	P48729	CSNK1A1	S2429	T2422S	2422	Missense	distal	-7	no	21.026	21.475	EPSD	COSMIC	20.411	Up-regulation
CK1_CK1_CK1-A_CSNK1A1_ST	P25054	APC	P48729	CSNK1A1	S2429	R2434I	2434	Missense	distal	5	no	21.026	20.661	EPSD	COSMIC	20.411	Down-regulation
CK1_CK1_CK1-A_CSNK1A1_ST	P25054	APC	P48729	CSNK1A1	S2461	S2466F	2466	Missense	distal	5	no	20.924	21.431	EPSD	COSMIC	20.411	Up-regulation
CK1_CK1_CK1-A_CSNK1A1_ST	P25054	APC	P48729	CSNK1A1	S2461	P2467S	2467	Missense	distal	6	no	20.924	21.150	EPSD	COSMIC;GDSC;CCLE	20.411	Up-regulation
CK1_CK1_CK1-A_CSNK1A1_ST	P25054	APC	P48729	CSNK1A1	S2461	P2467T	2467	Missense	distal	6	no	20.924	21.046	EPSD	COSMIC	20.411	Up-regulation
CK1_CK1_CK1-A_CSNK1A1_ST	P25054	APC	P48729	CSNK1A1	S2461	E2457G	2457	Missense	distal	-4	no	20.924	20.531	EPSD	COSMIC	20.411	Down-regulation
CK1_CK1_CK1-A_CSNK1A1_ST	P25054	APC	P48729	CSNK1A1	S2461	E2457D	2457	Missense	distal	-4	no	20.924	21.360	EPSD	COSMIC	20.411	Up-regulation
CK1_CK1_CK1-A_CSNK1A1_ST	P25054	APC	P48729	CSNK1A1	S2461	E2458V	2458	Missense	distal	-3	no	20.924	17.346	EPSD	COSMIC	20.411	Loss
CK1_CK1_CK1-A_CSNK1A1_ST	P25054	APC	P48729	CSNK1A1	S2461	S2466Y	2466	Missense	distal	5	no	20.924	21.351	EPSD	COSMIC	20.411	Up-regulation
CK1_CK1_CK1-A_CSNK1A1_ST	P25054	APC	P48729	CSNK1A1	S2461	E2463D	2463	Missense	proximal	2	no	20.924	21.115	EPSD	COSMIC	20.411	Up-regulation
CK1_CK1_CK1-A_CSNK1A1_ST	P25054	APC	P48729	CSNK1A1	S2464	P2467S	2467	Missense	distal	3	no	18.080	22.345	EPSD	COSMIC;GDSC;CCLE	20.411	Gain
CK1_CK1_CK1-A_CSNK1A1_ST	P25054	APC	P48729	CSNK1A1	S2466	S2466F	2466	Missense	central	0	yes	21.188	0.000	EPSD	COSMIC	20.411	Loss
CK1_CK1_CK1-A_CSNK1A1_ST	P25054	APC	P48729	CSNK1A1	S2466	P2467S	2467	Missense	proximal	1	no	21.188	21.035	EPSD	COSMIC;GDSC;CCLE	20.411	Down-regulation
CK1_CK1_CK1-A_CSNK1A1_ST	P25054	APC	P48729	CSNK1A1	S2466	P2467T	2467	Missense	proximal	1	no	21.188	21.044	EPSD	COSMIC	20.411	Down-regulation
CK1_CK1_CK1-A_CSNK1A1_ST	P25054	APC	P48729	CSNK1A1	S2466	R2470G	2470	Missense	distal	4	no	21.188	21.189	EPSD	COSMIC	20.411	Up-regulation
CK1_CK1_CK1-A_CSNK1A1_ST	P25054	APC	P48729	CSNK1A1	S2466	R2470T	2470	Missense	distal	4	no	21.188	21.123	EPSD	COSMIC	20.411	Down-regulation
CK1_CK1_CK1-A_CSNK1A1_ST	P25054	APC	P48729	CSNK1A1	S2466	R2470K	2470	Missense	distal	4	no	21.188	21.075	EPSD	COSMIC	20.411	Down-regulation
CK1_CK1_CK1-A_CSNK1A1_ST	P25054	APC	P48729	CSNK1A1	S2466	S2466Y	2466	Missense	central	0	yes	21.188	0.000	EPSD	COSMIC	20.411	Loss
CK1_CK1_CK1-A_CSNK1A1_ST	P25054	APC	P48729	CSNK1A1	S2466	S2473Y	2473	Missense	distal	7	no	21.188	21.441	EPSD	COSMIC	20.411	Up-regulation
CK1_CK1_CK1-A_CSNK1A1_ST	P25054	APC	P48729	CSNK1A1	S2466	E2463D	2463	Missense	distal	-3	no	21.188	23.663	EPSD	COSMIC	20.411	Up-regulation
CK1_CK1_CK1-A_CSNK1A1_ST	P25054	APC	P48729	CSNK1A1	S2531	R2530W	2530	Missense	proximal	-1	no	22.353	21.315	EPSD	COSMIC	20.411	Down-regulation
CK1_CK1_CK1-A_CSNK1A1_ST	P25054	APC	P48729	CSNK1A1	S2531	S2533F	2533	Missense	proximal	2	no	22.353	21.330	EPSD	COSMIC	20.411	Down-regulation
CK1_CK1_CK1-A_CSNK1A1_ST	P25054	APC	P48729	CSNK1A1	S2531	I2528V	2528	Missense	distal	-3	no	22.353	20.652	EPSD	COSMIC	20.411	Down-regulation
CK1_CK1_CK1-A_CSNK1A1_ST	P25054	APC	P48729	CSNK1A1	S2531	P2536S	2536	Missense	distal	5	no	22.353	22.105	EPSD	COSMIC	20.411	Down-regulation
CK1_CK1_CK1-A_CSNK1A1_ST	P25054	APC	P48729	CSNK1A1	S2531	D2527N	2527	Missense	distal	-4	no	22.353	18.615	EPSD	COSMIC	20.411	Loss
CK1_CK1_CK1-A_CSNK1A1_ST	P25054	APC	P48729	CSNK1A1	S2531	P2536T	2536	Missense	distal	5	no	22.353	22.316	EPSD	COSMIC	20.411	Down-regulation
CK1_CK1_CK1-A_CSNK1A1_ST	P25054	APC	P48729	CSNK1A1	S2533	R2530W	2530	Missense	distal	-3	no	17.688	20.958	EPSD	COSMIC	20.411	Gain
CK1_CK1_CK1-A_CSNK1A1_ST	P25054	APC	P48729	CSNK1A1	S2533	P2536S	2536	Missense	distal	3	no	17.688	21.953	EPSD	COSMIC	20.411	Gain
CK1_CK1_CK1-A_CSNK1A1_ST	P25054	APC	P48729	CSNK1A1	S2572	S2577L	2577	Missense	distal	5	no	22.288	22.600	EPSD	COSMIC	20.411	Up-regulation
CK1_CK1_CK1-A_CSNK1A1_ST	P25054	APC	P48729	CSNK1A1	S2572	R2565I	2565	Missense	distal	-7	no	22.288	22.225	EPSD	COSMIC	20.411	Down-regulation
CK1_CK1_CK1-A_CSNK1A1_ST	P25054	APC	P48729	CSNK1A1	S2572	R2565K	2565	Missense	distal	-7	no	22.288	22.669	EPSD	COSMIC	20.411	Up-regulation
CK1_CK1_CK1-A_CSNK1A1_ST	P25054	APC	P48729	CSNK1A1	S2572	R2566I	2566	Missense	distal	-6	no	22.288	21.810	EPSD	COSMIC	20.411	Down-regulation
CK1_CK1_CK1-A_CSNK1A1_ST	P25054	APC	P48729	CSNK1A1	S2572	S2570L	2570	Missense	proximal	-2	no	22.288	19.434	EPSD	COSMIC	20.411	Loss
CK1_CK1_CK1-A_CSNK1A1_ST	P25054	APC	P48729	CSNK1A1	S2572	I2573V	2573	Missense	proximal	1	no	22.288	22.101	EPSD	COSMIC	20.411	Down-regulation
CK1_CK1_CK1-A_CSNK1A1_ST	P25054	APC	P48729	CSNK1A1	S2572	S2569R	2569	Missense	distal	-3	no	22.288	18.062	EPSD	COSMIC;GDSC;CCLE	20.411	Loss
CK1_CK1_CK1-A_CSNK1A1_ST	P25054	APC	P48729	CSNK1A1	S2575	S2577L	2577	Missense	proximal	2	no	24.897	23.912	EPSD	COSMIC	20.411	Down-regulation
CK1_CK1_CK1-A_CSNK1A1_ST	P25054	APC	P48729	CSNK1A1	S2575	S2581N	2581	Missense	distal	6	no	24.897	24.680	EPSD	COSMIC	20.411	Down-regulation
CK1_CK1_CK1-A_CSNK1A1_ST	P25054	APC	P48729	CSNK1A1	S2575	S2570L	2570	Missense	distal	-5	no	24.897	24.268	EPSD	COSMIC	20.411	Down-regulation
CK1_CK1_CK1-A_CSNK1A1_ST	P25054	APC	P48729	CSNK1A1	S2575	I2573V	2573	Missense	proximal	-2	no	24.897	24.719	EPSD	COSMIC	20.411	Down-regulation
CK1_CK1_CK1-A_CSNK1A1_ST	P25054	APC	P48729	CSNK1A1	S2575	S2569R	2569	Missense	distal	-6	no	24.897	24.369	EPSD	COSMIC;GDSC;CCLE	20.411	Down-regulation
CK1_CK1_CK1-A_CSNK1A1_ST	P25054	APC	P48729	CSNK1A1	S2580	S2577L	2577	Missense	distal	-3	no	21.313	14.719	EPSD	COSMIC	20.411	Loss
CK1_CK1_CK1-A_CSNK1A1_ST	P25054	APC	P48729	CSNK1A1	S2580	S2581N	2581	Missense	proximal	1	no	21.313	21.257	EPSD	COSMIC	20.411	Down-regulation
CK1_CK1_CK1-A_CSNK1A1_ST	P25054	APC	P48729	CSNK1A1	S2580	I2573V	2573	Missense	distal	-7	no	21.313	19.262	EPSD	COSMIC	20.411	Loss
CK1_CK1_CK1-A_CSNK1A1_ST	P25054	APC	P48729	CSNK1A1	S2580	E2587K	2587	Missense	distal	7	no	21.313	21.442	EPSD	COSMIC	20.411	Up-regulation
CK1_CK1_CK1-A_CSNK1A1_ST	P25054	APC	P48729	CSNK1A1	T2635	A2638S	2638	Missense	distal	3	no	19.071	21.301	EPSD	COSMIC;GDSC;CCLE	20.411	Gain
CK1_CK1_CK1-A_CSNK1A1_ST	P25054	APC	P48729	CSNK1A1	S2674	R2670T	2670	Missense	distal	-4	no	20.899	21.297	EPSD	COSMIC	20.411	Up-regulation
CK1_CK1_CK1-A_CSNK1A1_ST	P25054	APC	P48729	CSNK1A1	S2674	N2667D	2667	Missense	distal	-7	no	20.899	20.955	EPSD	COSMIC	20.411	Up-regulation
CK1_CK1_CK1-A_CSNK1A1_ST	P25054	APC	P48729	CSNK1A1	S2674	S2674F	2674	Missense	central	0	yes	20.899	0.000	EPSD	COSMIC	20.411	Loss
CK1_CK1_CK1-A_CSNK1A1_ST	P25054	APC	P48729	CSNK1A1	S2674	R2670I	2670	Missense	distal	-4	no	20.899	20.733	EPSD	COSMIC	20.411	Down-regulation
CK1_CK1_CK1-A_CSNK1A1_ST	P25054	APC	P48729	CSNK1A1	S2685	V2682M	2682	Missense	distal	-3	no	19.772	23.199	EPSD	COSMIC	20.411	Gain
CK1_CK1_CK1-A_CSNK1A1_ST	P25054	APC	P48729	CSNK1A1	S2687	V2682M	2682	Missense	distal	-5	no	19.051	21.396	EPSD	COSMIC	20.411	Gain
CK1_CK1_CK1-A_CSNK1A1_ST	P25054	APC	P48729	CSNK1A1	S2768	S2766N	2766	Missense	proximal	-2	no	20.854	18.612	EPSD	COSMIC	20.411	Loss
CK1_CK1_CK1-A_CSNK1A1_ST	P25054	APC	P48729	CSNK1A1	S2768	S2772P	2772	Missense	distal	4	no	20.854	20.817	EPSD	COSMIC	20.411	Down-regulation
CK1_CK1_CK1-A_CSNK1A1_ST	P25054	APC	P48729	CSNK1A1	S2768	S2763N	2763	Missense	distal	-5	no	20.854	20.682	EPSD	COSMIC	20.411	Down-regulation
CK1_CK1_CK1-A_CSNK1A1_ST	P25054	APC	P48729	CSNK1A1	S2768	S2764Y	2764	Missense	distal	-4	no	20.854	18.301	EPSD	COSMIC	20.411	Loss
CK1_CK1_CK1-A_CSNK1A1_ST	P25054	APC	P48729	CSNK1A1	S2771	S2766N	2766	Missense	distal	-5	no	22.693	22.522	EPSD	COSMIC	20.411	Down-regulation
CK1_CK1_CK1-A_CSNK1A1_ST	P25054	APC	P48729	CSNK1A1	S2771	S2772P	2772	Missense	proximal	1	no	22.693	22.846	EPSD	COSMIC	20.411	Up-regulation
CK1_CK1_CK1-A_CSNK1A1_ST	P25054	APC	P48729	CSNK1A1	S2771	S2764Y	2764	Missense	distal	-7	no	22.693	21.225	EPSD	COSMIC	20.411	Down-regulation
CK1_CK1_CK1-A_CSNK1A1_ST	O60260	PRKN	P48729	CSNK1A1	T83	P88R	88	Missense	distal	5	no	20.260	20.421	EPSD	COSMIC	20.411	Gain
CK1_CK1_CK1-A_CSNK1A1_ST	O60260	PRKN	P48729	CSNK1A1	T83	A82E	82	Missense	proximal	-1	no	20.260	21.447	EPSD	COSMIC	20.411	Gain
CK1_CK1_CK1-A_CSNK1A1_ST	O60260	PRKN	P48729	CSNK1A1	T83	R89G	89	Missense	distal	6	no	20.260	20.471	EPSD	COSMIC	20.411	Gain
CK1_CK1_CK1-A_CSNK1A1_ST	O60260	PRKN	P48729	CSNK1A1	S136	P132Q	132	Missense	distal	-4	no	19.045	21.918	EPSD	COSMIC	20.411	Gain
CK1_CK1_CK1-A_CSNK1A1_ST	O60260	PRKN	P48729	CSNK1A1	S136	P132S	132	Missense	distal	-4	no	19.045	21.737	EPSD	COSMIC	20.411	Gain
CK1_CK1_CK1-A_CSNK1A1_ST	O60260	PRKN	P48729	CSNK1A1	S378	V380L	380	Missense	proximal	2	no	22.299	22.587	PhosphoSitePlus;EPSD	COSMIC	20.411	Up-regulation
CK1_CK1_CK1-A_CSNK1A1_ST	O60260	PRKN	P48729	CSNK1A1	S378	A371T	371	Missense	distal	-7	no	22.299	21.327	PhosphoSitePlus;EPSD	COSMIC	20.411	Down-regulation
CK1_CK1_CK1-A_CSNK1A1_ST	O60260	PRKN	P48729	CSNK1A1	S378	A379V	379	Missense	proximal	1	no	22.299	22.322	PhosphoSitePlus;EPSD	COSMIC	20.411	Up-regulation
CK1_CK1_CK1-A_CSNK1A1_ST	O60260	PRKN	P48729	CSNK1A1	S378	S378G	378	Missense	central	0	yes	22.299	0.000	PhosphoSitePlus;EPSD	COSMIC	20.411	Loss
CK1_CK1_CK1-A_CSNK1A1_ST	O60260	PRKN	P48729	CSNK1A1	S378	G375W	375	Missense	distal	-3	no	22.299	23.034	PhosphoSitePlus;EPSD	COSMIC	20.411	Up-regulation
CK1_CK1_CK1-A_CSNK1A1_ST	O60260	PRKN	P48729	CSNK1A1	S378	H373R	373	Missense	distal	-5	no	22.299	22.797	PhosphoSitePlus;EPSD	COSMIC	20.411	Up-regulation
CK1_CK1_CK1-A_CSNK1A1_ST	O60260	PRKN	P48729	CSNK1A1	S378	E382D	382	Missense	distal	4	no	22.299	22.228	PhosphoSitePlus;EPSD	COSMIC	20.411	Down-regulation
CK1_CK1_CK1-A_CSNK1A1_ST	O60260	PRKN	P48729	CSNK1A1	S378	G385E	385	Missense	distal	7	no	22.299	22.153	PhosphoSitePlus;EPSD	COSMIC	20.411	Down-regulation
CK1_CK1_CK1-A_CSNK1A1_ST	O60260	PRKN	P48729	CSNK1A1	S378	H373D	373	Missense	distal	-5	no	22.299	23.747	PhosphoSitePlus;EPSD	COSMIC	20.411	Up-regulation
CK1_CK1_CK1-A_CSNK1A1_ST	O60260	PRKN	P48729	CSNK1A1	S378	E376K	376	Missense	proximal	-2	no	22.299	20.986	PhosphoSitePlus;EPSD	COSMIC	20.411	Down-regulation
CK1_CK1_CK1-A_CSNK1A1_ST	P08238	HSP90AB1	P48729	CSNK1A1	T166	R168H	168	Missense	proximal	2	no	20.706	19.981	EPSD	COSMIC	20.411	Loss
CK1_CK1_CK1-A_CSNK1A1_ST	P08238	HSP90AB1	P48729	CSNK1A1	T166	R168G	168	Missense	proximal	2	no	20.706	21.658	EPSD	COSMIC	20.411	Up-regulation
CK1_CK1_CK1-A_CSNK1A1_ST	P08238	HSP90AB1	P48729	CSNK1A1	S226	E232K	232	Missense	distal	6	no	20.638	20.550	EPSD	COSMIC	20.411	Down-regulation
CK1_CK1_CK1-A_CSNK1A1_ST	P08238	HSP90AB1	P48729	CSNK1A1	S226	E231D	231	Missense	distal	5	no	20.638	20.845	EPSD	COSMIC	20.411	Up-regulation
CK1_CK1_CK1-A_CSNK1A1_ST	P08238	HSP90AB1	P48729	CSNK1A1	S255	E258D	258	Missense	distal	3	no	23.176	23.316	EPSD	COSMIC	20.411	Up-regulation
CK1_CK1_CK1-A_CSNK1A1_ST	P08238	HSP90AB1	P48729	CSNK1A1	S255	E258G	258	Missense	distal	3	no	23.176	23.042	EPSD	COSMIC	20.411	Down-regulation
CK1_CK1_CK1-A_CSNK1A1_ST	P08238	HSP90AB1	P48729	CSNK1A1	S261	E258D	258	Missense	distal	-3	no	22.901	25.377	EPSD	COSMIC	20.411	Up-regulation
CK1_CK1_CK1-A_CSNK1A1_ST	P08238	HSP90AB1	P48729	CSNK1A1	S261	E258G	258	Missense	distal	-3	no	22.901	23.314	EPSD	COSMIC	20.411	Up-regulation
CK1_CK1_CK1-A_CSNK1A1_ST	P08238	HSP90AB1	P48729	CSNK1A1	T297	T297A	297	Missense	central	0	yes	20.976	0.000	EPSD	COSMIC	20.411	Loss
CK1_CK1_CK1-A_CSNK1A1_ST	P08238	HSP90AB1	P48729	CSNK1A1	S468	T467I	467	Missense	proximal	-1	no	24.642	25.797	EPSD	COSMIC	20.411	Up-regulation
CK1_CK1_CK1-A_CSNK1A1_ST	P08238	HSP90AB1	P48729	CSNK1A1	S468	E471Q	471	Missense	distal	3	no	24.642	22.071	EPSD	COSMIC	20.411	Down-regulation
CK1_CK1_CK1-A_CSNK1A1_ST	P08238	HSP90AB1	P48729	CSNK1A1	S468	Y472C	472	Missense	distal	4	no	24.642	24.665	EPSD	COSMIC	20.411	Up-regulation
CK1_CK1_CK1-A_CSNK1A1_ST	P08238	HSP90AB1	P48729	CSNK1A1	S468	Y472H	472	Missense	distal	4	no	24.642	24.682	EPSD	COSMIC;GDSC;CCLE	20.411	Up-regulation
CK1_CK1_CK1-A_CSNK1A1_ST	P08238	HSP90AB1	P48729	CSNK1A1	S468	V473A	473	Missense	distal	5	no	24.642	24.610	EPSD	COSMIC;GDSC;CCLE	20.411	Down-regulation
CK1_CK1_CK1-A_CSNK1A1_ST	P08238	HSP90AB1	P48729	CSNK1A1	S669	G667D	667	Missense	proximal	-2	no	25.613	25.645	EPSD	COSMIC	20.411	Up-regulation
CK1_CK1_CK1-A_CSNK1A1_ST	P08238	HSP90AB1	P48729	CSNK1A1	S669	D672G	672	Missense	distal	3	no	25.613	25.339	EPSD	COSMIC	20.411	Down-regulation
CK1_CK1_CK1-A_CSNK1A1_ST	O75581	LRP6	P48729	CSNK1A1	S171	R173H	173	Missense	proximal	2	no	21.268	20.542	EPSD	COSMIC	20.411	Down-regulation
CK1_CK1_CK1-A_CSNK1A1_ST	O75581	LRP6	P48729	CSNK1A1	S172	R173H	173	Missense	proximal	1	no	25.826	25.739	EPSD	COSMIC	20.411	Down-regulation
CK1_CK1_CK1-A_CSNK1A1_ST	O75581	LRP6	P48729	CSNK1A1	S1025	S1020G	1020	Missense	distal	-5	no	20.899	21.192	EPSD	COSMIC	20.411	Up-regulation
CK1_CK1_CK1-A_CSNK1A1_ST	O75581	LRP6	P48729	CSNK1A1	S1025	S1020I	1020	Missense	distal	-5	no	20.899	20.726	EPSD	COSMIC	20.411	Down-regulation
CK1_CK1_CK1-A_CSNK1A1_ST	O75581	LRP6	P48729	CSNK1A1	T1408	G1406W	1406	Missense	proximal	-2	no	23.662	23.268	EPSD	COSMIC	20.411	Down-regulation
CK1_CK1_CK1-A_CSNK1A1_ST	O75581	LRP6	P48729	CSNK1A1	T1408	N1411T	1411	Missense	distal	3	no	23.662	23.707	EPSD	COSMIC	20.411	Up-regulation
CK1_CK1_CK1-A_CSNK1A1_ST	O75581	LRP6	P48729	CSNK1A1	S1444	S1447N	1447	Missense	distal	3	no	22.395	19.917	EPSD	COSMIC	20.411	Loss
CK1_CK1_CK1-A_CSNK1A1_ST	O75581	LRP6	P48729	CSNK1A1	S1472	S1469A	1469	Missense	distal	-3	no	20.721	16.265	EPSD	COSMIC	20.411	Loss
CK1_CK1_CK1-A_CSNK1A1_ST	O75581	LRP6	P48729	CSNK1A1	S1475	S1469A	1469	Missense	distal	-6	no	25.945	25.037	EPSD	COSMIC	20.411	Down-regulation
CK1_CK1_CK1-A_CSNK1A1_ST	Q12778	FOXO1	P48729	CSNK1A1	S164	R157C	157	Missense	distal	-7	no	21.680	20.622	EPSD	COSMIC	20.411	Down-regulation
CK1_CK1_CK1-A_CSNK1A1_ST	Q12778	FOXO1	P48729	CSNK1A1	S164	W160C	160	Missense	distal	-4	no	21.680	19.782	EPSD	COSMIC	20.411	Loss
CK1_CK1_CK1-A_CSNK1A1_ST	Q12778	FOXO1	P48729	CSNK1A1	S164	D167N	167	Missense	distal	3	no	21.680	18.480	EPSD	COSMIC;GDSC;CCLE	20.411	Loss
CK1_CK1_CK1-A_CSNK1A1_ST	Q12778	FOXO1	P48729	CSNK1A1	S164	Y165H	165	Missense	proximal	1	no	21.680	21.609	EPSD	COSMIC	20.411	Down-regulation
CK1_CK1_CK1-A_CSNK1A1_ST	Q12778	FOXO1	P48729	CSNK1A1	S164	G161D	161	Missense	distal	-3	no	21.680	23.742	EPSD	COSMIC	20.411	Up-regulation
CK1_CK1_CK1-A_CSNK1A1_ST	Q12778	FOXO1	P48729	CSNK1A1	S205	S203N	203	Missense	proximal	-2	no	30.590	28.348	EPSD	COSMIC	20.411	Down-regulation
CK1_CK1_CK1-A_CSNK1A1_ST	Q12778	FOXO1	P48729	CSNK1A1	S205	N204K	204	Missense	proximal	-1	no	30.590	30.143	EPSD	COSMIC	20.411	Down-regulation
CK1_CK1_CK1-A_CSNK1A1_ST	Q12778	FOXO1	P48729	CSNK1A1	S205	S203R	203	Missense	proximal	-2	no	30.590	29.500	EPSD	COSMIC	20.411	Down-regulation
CK1_CK1_CK1-A_CSNK1A1_ST	Q12778	FOXO1	P48729	CSNK1A1	S205	D199H	199	Missense	distal	-6	no	30.590	29.219	EPSD	COSMIC	20.411	Down-regulation
CK1_CK1_CK1-A_CSNK1A1_ST	Q12778	FOXO1	P48729	CSNK1A1	S205	S205N	205	Missense	central	0	yes	30.590	0.000	EPSD	COSMIC	20.411	Loss
CK1_CK1_CK1-A_CSNK1A1_ST	Q12778	FOXO1	P48729	CSNK1A1	S205	K210R	210	Missense	distal	5	no	30.590	30.588	EPSD	COSMIC	20.411	Down-regulation
CK1_CK1_CK1-A_CSNK1A1_ST	Q12778	FOXO1	P48729	CSNK1A1	S206	S203N	203	Missense	distal	-3	no	20.936	16.027	EPSD	COSMIC	20.411	Loss
CK1_CK1_CK1-A_CSNK1A1_ST	Q12778	FOXO1	P48729	CSNK1A1	S206	N204K	204	Missense	proximal	-2	no	20.936	21.863	EPSD	COSMIC	20.411	Up-regulation
CK1_CK1_CK1-A_CSNK1A1_ST	Q12778	FOXO1	P48729	CSNK1A1	S206	S205T	205	Missense	proximal	-1	no	20.936	20.538	EPSD	COSMIC;CCLE	20.411	Down-regulation
CK1_CK1_CK1-A_CSNK1A1_ST	Q12778	FOXO1	P48729	CSNK1A1	S206	S203R	203	Missense	distal	-3	no	20.936	16.710	EPSD	COSMIC	20.411	Loss
CK1_CK1_CK1-A_CSNK1A1_ST	Q12778	FOXO1	P48729	CSNK1A1	S206	D199H	199	Missense	distal	-7	no	20.936	19.592	EPSD	COSMIC	20.411	Loss
CK1_CK1_CK1-A_CSNK1A1_ST	Q12778	FOXO1	P48729	CSNK1A1	S206	S205N	205	Missense	proximal	-1	no	20.936	20.797	EPSD	COSMIC	20.411	Down-regulation
CK1_CK1_CK1-A_CSNK1A1_ST	Q12778	FOXO1	P48729	CSNK1A1	S206	K210R	210	Missense	distal	4	no	20.936	21.049	EPSD	COSMIC	20.411	Up-regulation
CK1_CK1_CK1-A_CSNK1A1_ST	Q12778	FOXO1	P48729	CSNK1A1	S212	S218F	218	Missense	distal	6	no	24.169	23.592	EPSD	COSMIC	20.411	Down-regulation
CK1_CK1_CK1-A_CSNK1A1_ST	Q12778	FOXO1	P48729	CSNK1A1	S212	N216K	216	Missense	distal	4	no	24.169	24.164	EPSD	COSMIC	20.411	Down-regulation
CK1_CK1_CK1-A_CSNK1A1_ST	Q12778	FOXO1	P48729	CSNK1A1	S212	S205T	205	Missense	distal	-7	no	24.169	23.720	EPSD	COSMIC;CCLE	20.411	Down-regulation
CK1_CK1_CK1-A_CSNK1A1_ST	Q12778	FOXO1	P48729	CSNK1A1	S212	S205N	205	Missense	distal	-7	no	24.169	24.373	EPSD	COSMIC	20.411	Up-regulation
CK1_CK1_CK1-A_CSNK1A1_ST	Q12778	FOXO1	P48729	CSNK1A1	S212	K210R	210	Missense	proximal	-2	no	24.169	24.394	EPSD	COSMIC	20.411	Up-regulation
CK1_CK1_CK1-A_CSNK1A1_ST	Q12778	FOXO1	P48729	CSNK1A1	S279	L277F	277	Missense	proximal	-2	no	20.194	21.181	EPSD	COSMIC	20.411	Gain
CK1_CK1_CK1-A_CSNK1A1_ST	Q12778	FOXO1	P48729	CSNK1A1	S287	S287N	287	Missense	central	0	yes	21.575	0.000	EPSD	COSMIC	20.411	Loss
CK1_CK1_CK1-A_CSNK1A1_ST	Q12778	FOXO1	P48729	CSNK1A1	S303	N309D	309	Missense	distal	6	no	21.233	21.380	EPSD	COSMIC;GDSC;CCLE	20.411	Up-regulation
CK1_CK1_CK1-A_CSNK1A1_ST	Q12778	FOXO1	P48729	CSNK1A1	S303	H302Y	302	Missense	proximal	-1	no	21.233	21.494	EPSD	COSMIC	20.411	Up-regulation
CK1_CK1_CK1-A_CSNK1A1_ST	Q12778	FOXO1	P48729	CSNK1A1	S303	W310C	310	Missense	distal	7	no	21.233	20.903	EPSD	COSMIC	20.411	Down-regulation
CK1_CK1_CK1-A_CSNK1A1_ST	Q12778	FOXO1	P48729	CSNK1A1	S311	N309D	309	Missense	proximal	-2	no	19.506	21.631	EPSD	COSMIC;GDSC;CCLE	20.411	Gain
CK1_CK1_CK1-A_CSNK1A1_ST	Q12778	FOXO1	P48729	CSNK1A1	S322	P315F	315	Missense	distal	-7	no	25.541	25.788	EPSD;PhosphoSitePlus	COSMIC	20.411	Up-regulation
CK1_CK1_CK1-A_CSNK1A1_ST	Q12778	FOXO1	P48729	CSNK1A1	S432	P438H	438	Missense	distal	6	no	20.532	20.494	EPSD	COSMIC	20.411	Down-regulation
CK1_CK1_CK1-A_CSNK1A1_ST	Q12778	FOXO1	P48729	CSNK1A1	S432	S432N	432	Missense	central	0	yes	20.532	0.000	EPSD	COSMIC	20.411	Loss
CK1_CK1_CK1-A_CSNK1A1_ST	Q12778	FOXO1	P48729	CSNK1A1	S432	I439V	439	Missense	distal	7	no	20.532	20.821	EPSD	COSMIC	20.411	Up-regulation
CK1_CK1_CK1-A_CSNK1A1_ST	Q12778	FOXO1	P48729	CSNK1A1	S432	G427V	427	Missense	distal	-5	no	20.532	18.479	EPSD	COSMIC	20.411	Loss
CK1_CK1_CK1-A_CSNK1A1_ST	Q12778	FOXO1	P48729	CSNK1A1	S509	S512F	512	Missense	distal	3	no	20.770	18.309	EPSD	COSMIC	20.411	Loss
CK1_CK1_CK1-A_CSNK1A1_ST	Q12778	FOXO1	P48729	CSNK1A1	S509	G508D	508	Missense	proximal	-1	no	20.770	20.497	EPSD	COSMIC	20.411	Down-regulation
CK1_CK1_CK1-A_CSNK1A1_ST	P40337	VHL	P48729	CSNK1A1	S33	S38F	38	Missense	distal	5	no	25.228	25.735	EPSD	COSMIC	20.411	Up-regulation
CK1_CK1_CK1-A_CSNK1A1_ST	P40337	VHL	P48729	CSNK1A1	S33	G39D	39	Missense	distal	6	no	25.228	25.139	EPSD	COSMIC	20.411	Down-regulation
CK1_CK1_CK1-A_CSNK1A1_ST	P40337	VHL	P48729	CSNK1A1	S33	P40L	40	Missense	distal	7	no	25.228	25.076	EPSD	COSMIC	20.411	Down-regulation
CK1_CK1_CK1-A_CSNK1A1_ST	P40337	VHL	P48729	CSNK1A1	S33	E26K	26	Missense	distal	-7	no	25.228	25.466	EPSD	COSMIC	20.411	Up-regulation
CK1_CK1_CK1-A_CSNK1A1_ST	P40337	VHL	P48729	CSNK1A1	S33	D28G	28	Missense	distal	-5	no	25.228	25.443	EPSD	COSMIC	20.411	Up-regulation
CK1_CK1_CK1-A_CSNK1A1_ST	P40337	VHL	P48729	CSNK1A1	S33	G39S	39	Missense	distal	6	no	25.228	25.210	EPSD	COSMIC	20.411	Down-regulation
CK1_CK1_CK1-A_CSNK1A1_ST	P40337	VHL	P48729	CSNK1A1	S33	S33A	33	Missense	central	0	yes	25.228	0.000	EPSD	COSMIC	20.411	Loss
CK1_CK1_CK1-A_CSNK1A1_ST	P40337	VHL	P48729	CSNK1A1	S33	G29D	29	Missense	distal	-4	no	25.228	26.057	EPSD	COSMIC	20.411	Up-regulation
CK1_CK1_CK1-A_CSNK1A1_ST	P40337	VHL	P48729	CSNK1A1	S33	D28V	28	Missense	distal	-5	no	25.228	23.390	EPSD	COSMIC	20.411	Down-regulation
CK1_CK1_CK1-A_CSNK1A1_ST	P40337	VHL	P48729	CSNK1A1	S33	P40S	40	Missense	distal	7	no	25.228	25.040	EPSD	COSMIC	20.411	Down-regulation
CK1_CK1_CK1-A_CSNK1A1_ST	P40337	VHL	P48729	CSNK1A1	S33	D28N	28	Missense	distal	-5	no	25.228	24.978	EPSD	COSMIC	20.411	Down-regulation
CK1_CK1_CK1-A_CSNK1A1_ST	P40337	VHL	P48729	CSNK1A1	S33	A35S	35	Missense	proximal	2	no	25.228	26.058	EPSD	COSMIC	20.411	Up-regulation
CK1_CK1_CK1-A_CSNK1A1_ST	P40337	VHL	P48729	CSNK1A1	S33	E37K	37	Missense	distal	4	no	25.228	25.039	EPSD	COSMIC	20.411	Down-regulation
CK1_CK1_CK1-A_CSNK1A1_ST	P40337	VHL	P48729	CSNK1A1	S33	G34C	34	Missense	proximal	1	no	25.228	24.804	EPSD	COSMIC	20.411	Down-regulation
CK1_CK1_CK1-A_CSNK1A1_ST	P40337	VHL	P48729	CSNK1A1	S33	E31G	31	Missense	proximal	-2	no	25.228	25.080	EPSD	COSMIC	20.411	Down-regulation
CK1_CK1_CK1-A_CSNK1A1_ST	P40337	VHL	P48729	CSNK1A1	S38	E42V	42	Missense	distal	4	no	24.264	24.065	EPSD	COSMIC	20.411	Down-regulation
CK1_CK1_CK1-A_CSNK1A1_ST	P40337	VHL	P48729	CSNK1A1	S38	S38F	38	Missense	central	0	yes	24.264	0.000	EPSD	COSMIC	20.411	Loss
CK1_CK1_CK1-A_CSNK1A1_ST	P40337	VHL	P48729	CSNK1A1	S38	G39D	39	Missense	proximal	1	no	24.264	24.218	EPSD	COSMIC	20.411	Down-regulation
CK1_CK1_CK1-A_CSNK1A1_ST	P40337	VHL	P48729	CSNK1A1	S38	P40L	40	Missense	proximal	2	no	24.264	24.294	EPSD	COSMIC	20.411	Up-regulation
CK1_CK1_CK1-A_CSNK1A1_ST	P40337	VHL	P48729	CSNK1A1	S38	P45R	45	Missense	distal	7	no	24.264	24.184	EPSD	COSMIC;CCLE	20.411	Down-regulation
CK1_CK1_CK1-A_CSNK1A1_ST	P40337	VHL	P48729	CSNK1A1	S38	G39S	39	Missense	proximal	1	no	24.264	24.044	EPSD	COSMIC	20.411	Down-regulation
CK1_CK1_CK1-A_CSNK1A1_ST	P40337	VHL	P48729	CSNK1A1	S38	S33A	33	Missense	distal	-5	no	24.264	22.953	EPSD	COSMIC	20.411	Down-regulation
CK1_CK1_CK1-A_CSNK1A1_ST	P40337	VHL	P48729	CSNK1A1	S38	P45L	45	Missense	distal	7	no	24.264	24.112	EPSD	COSMIC	20.411	Down-regulation
CK1_CK1_CK1-A_CSNK1A1_ST	P40337	VHL	P48729	CSNK1A1	S38	S43F	43	Missense	distal	5	no	24.264	24.772	EPSD	COSMIC	20.411	Up-regulation
CK1_CK1_CK1-A_CSNK1A1_ST	P40337	VHL	P48729	CSNK1A1	S38	P40S	40	Missense	proximal	2	no	24.264	25.280	EPSD	COSMIC	20.411	Up-regulation
CK1_CK1_CK1-A_CSNK1A1_ST	P40337	VHL	P48729	CSNK1A1	S38	E41V	41	Missense	distal	3	no	24.264	21.097	EPSD	COSMIC	20.411	Down-regulation
CK1_CK1_CK1-A_CSNK1A1_ST	P40337	VHL	P48729	CSNK1A1	S38	G44D	44	Missense	distal	6	no	24.264	24.175	EPSD	COSMIC	20.411	Down-regulation
CK1_CK1_CK1-A_CSNK1A1_ST	P40337	VHL	P48729	CSNK1A1	S38	E41G	41	Missense	distal	3	no	24.264	24.130	EPSD	COSMIC	20.411	Down-regulation
CK1_CK1_CK1-A_CSNK1A1_ST	P40337	VHL	P48729	CSNK1A1	S38	A35S	35	Missense	distal	-3	no	24.264	28.721	EPSD	COSMIC	20.411	Up-regulation
CK1_CK1_CK1-A_CSNK1A1_ST	P40337	VHL	P48729	CSNK1A1	S38	E37K	37	Missense	proximal	-1	no	24.264	22.623	EPSD	COSMIC	20.411	Down-regulation
CK1_CK1_CK1-A_CSNK1A1_ST	P40337	VHL	P48729	CSNK1A1	S38	G34C	34	Missense	distal	-4	no	24.264	21.400	EPSD	COSMIC	20.411	Down-regulation
CK1_CK1_CK1-A_CSNK1A1_ST	P40337	VHL	P48729	CSNK1A1	S38	E42K	42	Missense	distal	4	no	24.264	24.075	EPSD	COSMIC	20.411	Down-regulation
CK1_CK1_CK1-A_CSNK1A1_ST	P40337	VHL	P48729	CSNK1A1	S38	P45S	45	Missense	distal	7	no	24.264	24.077	EPSD	COSMIC	20.411	Down-regulation
CK1_CK1_CK1-A_CSNK1A1_ST	P40337	VHL	P48729	CSNK1A1	S38	E31G	31	Missense	distal	-7	no	24.264	24.771	EPSD	COSMIC	20.411	Up-regulation
CK1_CK1_CK1-A_CSNK1A1_ST	P40337	VHL	P48729	CSNK1A1	S43	G39D	39	Missense	distal	-4	no	19.615	20.444	EPSD	COSMIC	20.411	Gain
CK1_CK1_CK1-A_CSNK1A1_ST	P40337	VHL	P48729	CSNK1A1	S43	P40S	40	Missense	distal	-3	no	19.615	25.803	EPSD	COSMIC	20.411	Gain
CK1_CK1_CK1-A_CSNK1A1_ST	P40337	VHL	P48729	CSNK1A1	S43	P45S	45	Missense	proximal	2	no	19.615	20.630	EPSD	COSMIC	20.411	Gain
CK1_CK1_CK1-A_CSNK1A1_ST	P40337	VHL	P48729	CSNK1A1	S72	N78T	78	Missense	distal	6	no	21.150	21.263	PhosphoSitePlus	COSMIC;CCLE	20.411	Up-regulation
CK1_CK1_CK1-A_CSNK1A1_ST	P40337	VHL	P48729	CSNK1A1	S72	S65T	65	Missense	distal	-7	no	21.150	20.701	PhosphoSitePlus	COSMIC	20.411	Down-regulation
CK1_CK1_CK1-A_CSNK1A1_ST	P40337	VHL	P48729	CSNK1A1	S72	S68T	68	Missense	distal	-4	no	21.150	19.516	PhosphoSitePlus	COSMIC	20.411	Loss
CK1_CK1_CK1-A_CSNK1A1_ST	P40337	VHL	P48729	CSNK1A1	S72	F76Y	76	Missense	distal	4	no	21.150	21.094	PhosphoSitePlus	COSMIC	20.411	Down-regulation
CK1_CK1_CK1-A_CSNK1A1_ST	P40337	VHL	P48729	CSNK1A1	S72	Q73H	73	Missense	proximal	1	no	21.150	20.724	PhosphoSitePlus	COSMIC	20.411	Down-regulation
CK1_CK1_CK1-A_CSNK1A1_ST	P40337	VHL	P48729	CSNK1A1	S72	P71T	71	Missense	proximal	-1	no	21.150	20.744	PhosphoSitePlus	COSMIC	20.411	Down-regulation
CK1_CK1_CK1-A_CSNK1A1_ST	P40337	VHL	P48729	CSNK1A1	S72	F76S	76	Missense	distal	4	no	21.150	21.237	PhosphoSitePlus	COSMIC	20.411	Up-regulation
CK1_CK1_CK1-A_CSNK1A1_ST	P40337	VHL	P48729	CSNK1A1	S72	F76L	76	Missense	distal	4	no	21.150	21.267	PhosphoSitePlus	COSMIC	20.411	Up-regulation
CK1_CK1_CK1-A_CSNK1A1_ST	P40337	VHL	P48729	CSNK1A1	S72	S65Q	65	Missense	distal	-7	no	21.150	21.238	PhosphoSitePlus	COSMIC	20.411	Up-regulation
CK1_CK1_CK1-A_CSNK1A1_ST	P40337	VHL	P48729	CSNK1A1	S72	S65A	65	Missense	distal	-7	no	21.150	21.673	PhosphoSitePlus	COSMIC	20.411	Up-regulation
CK1_CK1_CK1-A_CSNK1A1_ST	P40337	VHL	P48729	CSNK1A1	S72	C77S	77	Missense	distal	5	no	21.150	20.827	PhosphoSitePlus	COSMIC	20.411	Down-regulation
CK1_CK1_CK1-A_CSNK1A1_ST	P40337	VHL	P48729	CSNK1A1	S72	S72P	72	Missense	central	0	yes	21.150	0.000	PhosphoSitePlus	COSMIC	20.411	Loss
CK1_CK1_CK1-A_CSNK1A1_ST	P40337	VHL	P48729	CSNK1A1	S72	S68P	68	Missense	distal	-4	no	21.150	18.458	PhosphoSitePlus	COSMIC	20.411	Loss
CK1_CK1_CK1-A_CSNK1A1_ST	P40337	VHL	P48729	CSNK1A1	S72	Q73K	73	Missense	proximal	1	no	21.150	20.706	PhosphoSitePlus	COSMIC	20.411	Down-regulation
CK1_CK1_CK1-A_CSNK1A1_ST	P40337	VHL	P48729	CSNK1A1	S72	N67S	67	Missense	distal	-5	no	21.150	21.322	PhosphoSitePlus	COSMIC	20.411	Up-regulation
CK1_CK1_CK1-A_CSNK1A1_ST	P40337	VHL	P48729	CSNK1A1	S72	I75V	75	Missense	distal	3	no	21.150	19.822	PhosphoSitePlus	COSMIC	20.411	Loss
CK1_CK1_CK1-A_CSNK1A1_ST	P40337	VHL	P48729	CSNK1A1	S72	N78H	78	Missense	distal	6	no	21.150	21.104	PhosphoSitePlus	COSMIC	20.411	Down-regulation
CK1_CK1_CK1-A_CSNK1A1_ST	P40337	VHL	P48729	CSNK1A1	S72	S68L	68	Missense	distal	-4	no	21.150	17.343	PhosphoSitePlus	COSMIC	20.411	Loss
CK1_CK1_CK1-A_CSNK1A1_ST	P40337	VHL	P48729	CSNK1A1	S72	R69C	69	Missense	distal	-3	no	21.150	21.044	PhosphoSitePlus	COSMIC	20.411	Down-regulation
CK1_CK1_CK1-A_CSNK1A1_ST	P40337	VHL	P48729	CSNK1A1	S111	I109S	109	Missense	proximal	-2	no	18.398	20.577	EPSD	COSMIC	20.411	Gain
CK1_CK1_CK1-A_CSNK1A1_ST	P40337	VHL	P48729	CSNK1A1	S111	R107G	107	Missense	distal	-4	no	18.398	20.597	EPSD	COSMIC	20.411	Gain
CK1_CK1_CK1-A_CSNK1A1_ST	Q13501	SQSTM1	P48729	CSNK1A1	S152	D149N	149	Missense	distal	-3	no	20.756	15.476	EPSD	COSMIC	20.411	Loss
CK1_CK1_CK1-A_CSNK1A1_ST	Q13501	SQSTM1	P48729	CSNK1A1	S152	G158D	158	Missense	distal	6	no	20.756	20.667	EPSD	COSMIC	20.411	Down-regulation
CK1_CK1_CK1-A_CSNK1A1_ST	Q13501	SQSTM1	P48729	CSNK1A1	S176	R183C	183	Missense	distal	7	no	20.545	20.591	EPSD	COSMIC	20.411	Up-regulation
CK1_CK1_CK1-A_CSNK1A1_ST	Q13501	SQSTM1	P48729	CSNK1A1	S180	R183C	183	Missense	distal	3	no	26.136	24.536	EPSD	COSMIC	20.411	Down-regulation
CK1_CK1_CK1-A_CSNK1A1_ST	Q13501	SQSTM1	P48729	CSNK1A1	S182	R183C	183	Missense	proximal	1	no	21.169	21.019	EPSD	COSMIC	20.411	Down-regulation
CK1_CK1_CK1-A_CSNK1A1_ST	Q13501	SQSTM1	P48729	CSNK1A1	S224	S226F	226	Missense	proximal	2	no	23.092	22.069	EPSD	COSMIC	20.411	Down-regulation
CK1_CK1_CK1-A_CSNK1A1_ST	Q13501	SQSTM1	P48729	CSNK1A1	S224	T221M	221	Missense	distal	-3	no	23.092	24.600	EPSD	COSMIC	20.411	Up-regulation
CK1_CK1_CK1-A_CSNK1A1_ST	Q13501	SQSTM1	P48729	CSNK1A1	S226	S226F	226	Missense	central	0	yes	26.569	0.000	EPSD	COSMIC	20.411	Loss
CK1_CK1_CK1-A_CSNK1A1_ST	Q13501	SQSTM1	P48729	CSNK1A1	S226	T221M	221	Missense	distal	-5	no	26.569	27.786	EPSD	COSMIC	20.411	Up-regulation
CK1_CK1_CK1-A_CSNK1A1_ST	Q13501	SQSTM1	P48729	CSNK1A1	S229	S226F	226	Missense	distal	-3	no	20.534	14.882	EPSD	COSMIC	20.411	Loss
CK1_CK1_CK1-A_CSNK1A1_ST	Q13501	SQSTM1	P48729	CSNK1A1	S233	S226F	226	Missense	distal	-7	no	24.084	23.666	EPSD	COSMIC	20.411	Down-regulation
CK1_CK1_CK1-A_CSNK1A1_ST	Q13501	SQSTM1	P48729	CSNK1A1	S233	K238E	238	Missense	distal	5	no	24.084	23.639	EPSD	COSMIC	20.411	Down-regulation
CK1_CK1_CK1-A_CSNK1A1_ST	Q13501	SQSTM1	P48729	CSNK1A1	S277	E274D	274	Missense	distal	-3	no	19.086	21.561	EPSD	COSMIC	20.411	Gain
CK1_CK1_CK1-A_CSNK1A1_ST	Q13501	SQSTM1	P48729	CSNK1A1	S282	C289Y	289	Missense	distal	7	no	21.022	21.123	EPSD	COSMIC;GDSC;CCLE	20.411	Up-regulation
CK1_CK1_CK1-A_CSNK1A1_ST	Q13501	SQSTM1	P48729	CSNK1A1	S291	C289Y	289	Missense	proximal	-2	no	22.276	21.551	EPSD	COSMIC;GDSC;CCLE	20.411	Down-regulation
CK1_CK1_CK1-A_CSNK1A1_ST	Q13501	SQSTM1	P48729	CSNK1A1	S332	Q325E	325	Missense	distal	-7	no	20.729	21.187	EPSD	COSMIC	20.411	Up-regulation
CK1_CK1_CK1-A_CSNK1A1_ST	Q13501	SQSTM1	P48729	CSNK1A1	S349	T350I	350	Missense	proximal	1	no	22.063	22.227	PhosphoSitePlus	COSMIC	20.411	Up-regulation
CK1_CK1_CK1-A_CSNK1A1_ST	Q13501	SQSTM1	P48729	CSNK1A1	S361	P359S	359	Missense	proximal	-2	no	23.967	25.837	EPSD	COSMIC	20.411	Up-regulation
CK1_CK1_CK1-A_CSNK1A1_ST	Q13501	SQSTM1	P48729	CSNK1A1	S361	E362D	362	Missense	proximal	1	no	23.967	23.838	EPSD	COSMIC	20.411	Down-regulation
CK1_CK1_CK1-A_CSNK1A1_ST	Q13501	SQSTM1	P48729	CSNK1A1	S361	S365N	365	Missense	distal	4	no	23.967	23.887	EPSD	COSMIC	20.411	Down-regulation
CK1_CK1_CK1-A_CSNK1A1_ST	Q13501	SQSTM1	P48729	CSNK1A1	S361	E360K	360	Missense	proximal	-1	no	23.967	22.325	EPSD	COSMIC	20.411	Down-regulation
CK1_CK1_CK1-A_CSNK1A1_ST	Q13501	SQSTM1	P48729	CSNK1A1	S361	P364S	364	Missense	distal	3	no	23.967	28.232	EPSD	COSMIC	20.411	Up-regulation
CK1_CK1_CK1-A_CSNK1A1_ST	Q13501	SQSTM1	P48729	CSNK1A1	S365	P359S	359	Missense	distal	-6	no	20.464	21.145	EPSD	COSMIC	20.411	Up-regulation
CK1_CK1_CK1-A_CSNK1A1_ST	Q13501	SQSTM1	P48729	CSNK1A1	S365	E362D	362	Missense	distal	-3	no	20.464	22.940	EPSD	COSMIC	20.411	Up-regulation
CK1_CK1_CK1-A_CSNK1A1_ST	Q13501	SQSTM1	P48729	CSNK1A1	S365	S365N	365	Missense	central	0	yes	20.464	0.000	EPSD	COSMIC	20.411	Loss
CK1_CK1_CK1-A_CSNK1A1_ST	Q13501	SQSTM1	P48729	CSNK1A1	S365	E360K	360	Missense	distal	-5	no	20.464	19.846	EPSD	COSMIC	20.411	Loss
CK1_CK1_CK1-A_CSNK1A1_ST	Q13501	SQSTM1	P48729	CSNK1A1	S365	P364S	364	Missense	proximal	-1	no	20.464	20.456	EPSD	COSMIC	20.411	Down-regulation
CK1_CK1_CK1-A_CSNK1A1_ST	Q13501	SQSTM1	P48729	CSNK1A1	S370	P364S	364	Missense	distal	-6	no	19.953	20.634	EPSD	COSMIC	20.411	Gain
CK1_CK1_CK1-A_CSNK1A1_ST	P07910	HNRNPC	P48729	CSNK1A1	S107	Y105C	105	Missense	proximal	-2	no	23.470	24.195	EPSD	COSMIC;GDSC;CCLE	20.411	Up-regulation
CK1_CK1_CK1-A_CSNK1A1_ST	P07910	HNRNPC	P48729	CSNK1A1	S107	T109P	109	Missense	proximal	2	no	23.470	23.247	EPSD	COSMIC;GDSC;CCLE	20.411	Down-regulation
CK1_CK1_CK1-A_CSNK1A1_ST	P07910	HNRNPC	P48729	CSNK1A1	S107	P114S	114	Missense	distal	7	no	23.470	23.283	EPSD	COSMIC	20.411	Down-regulation
CK1_CK1_CK1-A_CSNK1A1_ST	P07910	HNRNPC	P48729	CSNK1A1	S113	P116S	116	Missense	distal	3	no	17.344	21.609	EPSD	COSMIC	20.411	Gain
CK1_CK1_CK1-A_CSNK1A1_ST	P07910	HNRNPC	P48729	CSNK1A1	S119	P116S	116	Missense	distal	-3	no	15.604	21.791	EPSD	COSMIC	20.411	Gain
CK1_CK1_CK1-A_CSNK1A1_ST	P07910	HNRNPC	P48729	CSNK1A1	S182	S177P	177	Missense	distal	-5	no	21.299	20.867	EPSD	COSMIC	20.411	Down-regulation
CK1_CK1_CK1-A_CSNK1A1_ST	P07910	HNRNPC	P48729	CSNK1A1	S182	S185F	185	Missense	distal	3	no	21.299	18.838	EPSD	COSMIC	20.411	Loss
CK1_CK1_CK1-A_CSNK1A1_ST	P07910	HNRNPC	P48729	CSNK1A1	S182	S177T	177	Missense	distal	-5	no	21.299	20.668	EPSD	COSMIC	20.411	Down-regulation
CK1_CK1_CK1-A_CSNK1A1_ST	P07910	HNRNPC	P48729	CSNK1A1	S182	Q179K	179	Missense	distal	-3	no	21.299	18.546	EPSD	COSMIC	20.411	Loss
CK1_CK1_CK1-A_CSNK1A1_ST	P07910	HNRNPC	P48729	CSNK1A1	S183	S177P	177	Missense	distal	-6	no	23.577	22.895	EPSD	COSMIC	20.411	Down-regulation
CK1_CK1_CK1-A_CSNK1A1_ST	P07910	HNRNPC	P48729	CSNK1A1	S183	S185F	185	Missense	proximal	2	no	23.577	22.555	EPSD	COSMIC	20.411	Down-regulation
CK1_CK1_CK1-A_CSNK1A1_ST	P07910	HNRNPC	P48729	CSNK1A1	S183	S177T	177	Missense	distal	-6	no	23.577	23.195	EPSD	COSMIC	20.411	Down-regulation
CK1_CK1_CK1-A_CSNK1A1_ST	P07910	HNRNPC	P48729	CSNK1A1	S183	Q179K	179	Missense	distal	-4	no	23.577	20.257	EPSD	COSMIC	20.411	Loss
CK1_CK1_CK1-A_CSNK1A1_ST	P07910	HNRNPC	P48729	CSNK1A1	S238	E235D	235	Missense	distal	-3	no	23.809	26.285	EPSD	COSMIC	20.411	Up-regulation
CK1_CK1_CK1-A_CSNK1A1_ST	P07910	HNRNPC	P48729	CSNK1A1	S238	D231G	231	Missense	distal	-7	no	23.809	24.601	EPSD	COSMIC	20.411	Up-regulation
CK1_CK1_CK1-A_CSNK1A1_ST	P07910	HNRNPC	P48729	CSNK1A1	S238	S233P	233	Missense	distal	-5	no	23.809	23.377	EPSD	COSMIC	20.411	Down-regulation
CK1_CK1_CK1-A_CSNK1A1_ST	P07910	HNRNPC	P48729	CSNK1A1	S238	D245N	245	Missense	distal	7	no	23.809	23.893	EPSD	COSMIC	20.411	Up-regulation
CK1_CK1_CK1-A_CSNK1A1_ST	P07910	HNRNPC	P48729	CSNK1A1	S238	S241F	241	Missense	distal	3	no	23.809	21.348	EPSD	COSMIC	20.411	Down-regulation
CK1_CK1_CK1-A_CSNK1A1_ST	P07910	HNRNPC	P48729	CSNK1A1	S238	V242L	242	Missense	distal	4	no	23.809	23.934	EPSD	COSMIC	20.411	Up-regulation
CK1_CK1_CK1-A_CSNK1A1_ST	P07910	HNRNPC	P48729	CSNK1A1	S238	Q237H	237	Missense	proximal	-1	no	23.809	22.132	EPSD	COSMIC	20.411	Down-regulation
CK1_CK1_CK1-A_CSNK1A1_ST	P07910	HNRNPC	P48729	CSNK1A1	S238	S240F	240	Missense	proximal	2	no	23.809	22.787	EPSD	COSMIC	20.411	Down-regulation
CK1_CK1_CK1-A_CSNK1A1_ST	P07910	HNRNPC	P48729	CSNK1A1	S238	D231N	231	Missense	distal	-7	no	23.809	23.752	EPSD	COSMIC	20.411	Down-regulation
CK1_CK1_CK1-A_CSNK1A1_ST	P07910	HNRNPC	P48729	CSNK1A1	S239	E235D	235	Missense	distal	-4	no	22.141	22.577	EPSD	COSMIC	20.411	Up-regulation
CK1_CK1_CK1-A_CSNK1A1_ST	P07910	HNRNPC	P48729	CSNK1A1	S239	S233P	233	Missense	distal	-6	no	22.141	21.460	EPSD	COSMIC	20.411	Down-regulation
CK1_CK1_CK1-A_CSNK1A1_ST	P07910	HNRNPC	P48729	CSNK1A1	S239	D245N	245	Missense	distal	6	no	22.141	21.995	EPSD	COSMIC	20.411	Down-regulation
CK1_CK1_CK1-A_CSNK1A1_ST	P07910	HNRNPC	P48729	CSNK1A1	S239	E246K	246	Missense	distal	7	no	22.141	22.270	EPSD	COSMIC	20.411	Up-regulation
CK1_CK1_CK1-A_CSNK1A1_ST	P07910	HNRNPC	P48729	CSNK1A1	S239	S241F	241	Missense	proximal	2	no	22.141	21.119	EPSD	COSMIC	20.411	Down-regulation
CK1_CK1_CK1-A_CSNK1A1_ST	P07910	HNRNPC	P48729	CSNK1A1	S239	V242L	242	Missense	distal	3	no	22.141	20.974	EPSD	COSMIC	20.411	Down-regulation
CK1_CK1_CK1-A_CSNK1A1_ST	P07910	HNRNPC	P48729	CSNK1A1	S239	Q237H	237	Missense	proximal	-2	no	22.141	20.013	EPSD	COSMIC	20.411	Loss
CK1_CK1_CK1-A_CSNK1A1_ST	P07910	HNRNPC	P48729	CSNK1A1	S239	S240F	240	Missense	proximal	1	no	22.141	22.085	EPSD	COSMIC	20.411	Down-regulation
CK1_CK1_CK1-A_CSNK1A1_ST	P07910	HNRNPC	P48729	CSNK1A1	S241	E235D	235	Missense	distal	-6	no	22.842	23.778	EPSD	COSMIC	20.411	Up-regulation
CK1_CK1_CK1-A_CSNK1A1_ST	P07910	HNRNPC	P48729	CSNK1A1	S241	D245N	245	Missense	distal	4	no	22.842	22.728	EPSD	COSMIC	20.411	Down-regulation
CK1_CK1_CK1-A_CSNK1A1_ST	P07910	HNRNPC	P48729	CSNK1A1	S241	E246K	246	Missense	distal	5	no	22.842	23.286	EPSD	COSMIC	20.411	Up-regulation
CK1_CK1_CK1-A_CSNK1A1_ST	P07910	HNRNPC	P48729	CSNK1A1	S241	S241F	241	Missense	central	0	yes	22.842	0.000	EPSD	COSMIC	20.411	Loss
CK1_CK1_CK1-A_CSNK1A1_ST	P07910	HNRNPC	P48729	CSNK1A1	S241	V242L	242	Missense	proximal	1	no	22.842	23.118	EPSD	COSMIC	20.411	Up-regulation
CK1_CK1_CK1-A_CSNK1A1_ST	P07910	HNRNPC	P48729	CSNK1A1	S241	Q237H	237	Missense	distal	-4	no	22.842	18.587	EPSD	COSMIC	20.411	Loss
CK1_CK1_CK1-A_CSNK1A1_ST	P07910	HNRNPC	P48729	CSNK1A1	S241	S240F	240	Missense	proximal	-1	no	22.842	22.139	EPSD	COSMIC	20.411	Down-regulation
CK1_CK1_CK1-A_CSNK1A1_ST	P07910	HNRNPC	P48729	CSNK1A1	S253	G255R	255	Missense	proximal	2	no	20.946	19.994	PhosphoSitePlus;EPSD	COSMIC	20.411	Loss
CK1_CK1_CK1-A_CSNK1A1_ST	P07910	HNRNPC	P48729	CSNK1A1	S253	E246K	246	Missense	distal	-7	no	20.946	21.184	PhosphoSitePlus;EPSD	COSMIC	20.411	Up-regulation
CK1_CK1_CK1-A_CSNK1A1_ST	P07910	HNRNPC	P48729	CSNK1A1	S253	E252Q	252	Missense	proximal	-1	no	20.946	20.421	PhosphoSitePlus;EPSD	COSMIC	20.411	Down-regulation
CK1_CK1_CK1-A_CSNK1A1_ST	P07910	HNRNPC	P48729	CSNK1A1	S253	E254Q	254	Missense	proximal	1	no	20.946	20.930	PhosphoSitePlus;EPSD	COSMIC	20.411	Down-regulation
CK1_CK1_CK1-A_CSNK1A1_ST	P07910	HNRNPC	P48729	CSNK1A1	S260	G255R	255	Missense	distal	-5	no	21.130	19.966	EPSD;PhosphoSitePlus	COSMIC	20.411	Loss
CK1_CK1_CK1-A_CSNK1A1_ST	P07910	HNRNPC	P48729	CSNK1A1	S260	A261V	261	Missense	proximal	1	no	21.130	21.153	EPSD;PhosphoSitePlus	COSMIC	20.411	Up-regulation
CK1_CK1_CK1-A_CSNK1A1_ST	P07910	HNRNPC	P48729	CSNK1A1	S260	E254Q	254	Missense	distal	-6	no	21.130	21.461	EPSD;PhosphoSitePlus	COSMIC	20.411	Up-regulation
CK1_CK1_CK1-A_CSNK1A1_ST	P07910	HNRNPC	P48729	CSNK1A1	S299	E303Q	303	Missense	distal	4	no	23.605	23.431	EPSD;PhosphoSitePlus	COSMIC;GDSC	20.411	Down-regulation
CK1_CK1_CK1-A_CSNK1A1_ST	P07910	HNRNPC	P48729	CSNK1A1	S299	S299R	299	Missense	central	0	yes	23.605	0.000	EPSD;PhosphoSitePlus	COSMIC;GDSC	20.411	Loss
CK1_CK1_CK1-A_CSNK1A1_ST	P07910	HNRNPC	P48729	CSNK1A1	S299	D295N	295	Missense	distal	-4	no	23.605	19.867	EPSD;PhosphoSitePlus	COSMIC	20.411	Loss
CK1_CK1_CK1-A_CSNK1A1_ST	Q8TB45	DEPTOR	P48729	CSNK1A1	S6	G4S	4	Missense	proximal	-2	no	22.103	22.252	EPSD	COSMIC;CCLE	20.411	Up-regulation
CK1_CK1_CK1-A_CSNK1A1_ST	Q8TB45	DEPTOR	P48729	CSNK1A1	S9	G4S	4	Missense	distal	-5	no	26.033	25.739	EPSD	COSMIC;CCLE	20.411	Down-regulation
CK1_CK1_CK1-A_CSNK1A1_ST	Q8TB45	DEPTOR	P48729	CSNK1A1	S282	S282G	282	Missense	central	0	yes	21.463	0.000	EPSD	COSMIC	20.411	Loss
CK1_CK1_CK1-A_CSNK1A1_ST	Q8TB45	DEPTOR	P48729	CSNK1A1	S282	C284Y	284	Missense	proximal	2	no	21.463	21.123	EPSD	COSMIC	20.411	Down-regulation
CK1_CK1_CK1-A_CSNK1A1_ST	Q8TB45	DEPTOR	P48729	CSNK1A1	S282	S286I	286	Missense	distal	4	no	21.463	21.484	EPSD	COSMIC	20.411	Up-regulation
CK1_CK1_CK1-A_CSNK1A1_ST	Q8TB45	DEPTOR	P48729	CSNK1A1	S286	S282G	282	Missense	distal	-4	no	23.573	23.738	EPSD;PhosphoSitePlus	COSMIC	20.411	Up-regulation
CK1_CK1_CK1-A_CSNK1A1_ST	Q8TB45	DEPTOR	P48729	CSNK1A1	S286	C284Y	284	Missense	proximal	-2	no	23.573	22.848	EPSD;PhosphoSitePlus	COSMIC	20.411	Down-regulation
CK1_CK1_CK1-A_CSNK1A1_ST	Q8TB45	DEPTOR	P48729	CSNK1A1	S286	S286I	286	Missense	central	0	yes	23.573	0.000	EPSD;PhosphoSitePlus	COSMIC	20.411	Loss
CK1_CK1_CK1-A_CSNK1A1_ST	Q04206	RELA	P48729	CSNK1A1	S45	E39Q	39	Missense	distal	-6	no	22.650	22.980	EPSD	COSMIC	20.411	Up-regulation
CK1_CK1_CK1-A_CSNK1A1_ST	Q04206	RELA	P48729	CSNK1A1	S131	R124W	124	Missense	distal	-7	no	21.220	19.184	EPSD	COSMIC	20.411	Loss
CK1_CK1_CK1-A_CSNK1A1_ST	Q04206	RELA	P48729	CSNK1A1	S316	M313I	313	Missense	distal	-3	no	21.058	19.332	PhosphoSitePlus	COSMIC	20.411	Loss
CK1_CK1_CK1-A_CSNK1A1_ST	Q04206	RELA	P48729	CSNK1A1	S316	K314N	314	Missense	proximal	-2	no	21.058	20.131	PhosphoSitePlus	COSMIC	20.411	Loss
CK1_CK1_CK1-A_CSNK1A1_ST	O60346	PHLPP1	P48729	CSNK1A1	S142	S149W	149	Missense	distal	7	no	23.204	23.688	EPSD	COSMIC	20.411	Up-regulation
CK1_CK1_CK1-A_CSNK1A1_ST	O60346	PHLPP1	P48729	CSNK1A1	S143	S149W	149	Missense	distal	6	no	21.270	20.583	EPSD	COSMIC	20.411	Down-regulation
CK1_CK1_CK1-A_CSNK1A1_ST	O60346	PHLPP1	P48729	CSNK1A1	S144	S149W	149	Missense	distal	5	no	21.796	22.479	EPSD	COSMIC	20.411	Up-regulation
CK1_CK1_CK1-A_CSNK1A1_ST	O60346	PHLPP1	P48729	CSNK1A1	S450	S450F	450	Missense	central	0	yes	22.514	0.000	EPSD	COSMIC	20.411	Loss
CK1_CK1_CK1-A_CSNK1A1_ST	O60346	PHLPP1	P48729	CSNK1A1	S1381	G1375E	1375	Missense	distal	-6	no	25.473	24.663	EPSD;PhosphoSitePlus	COSMIC	20.411	Down-regulation
CK1_CK1_CK1-A_CSNK1A1_ST	P07900	HSP90AA1	P48729	CSNK1A1	S164	Y160C	160	Missense	distal	-4	no	22.439	22.292	EPSD	COSMIC	20.411	Down-regulation
CK1_CK1_CK1-A_CSNK1A1_ST	P07900	HSP90AA1	P48729	CSNK1A1	S165	Y160C	160	Missense	distal	-5	no	26.788	27.430	EPSD	COSMIC	20.411	Up-regulation
CK1_CK1_CK1-A_CSNK1A1_ST	P07900	HSP90AA1	P48729	CSNK1A1	S263	V261G	261	Missense	proximal	-2	no	22.114	24.322	EPSD	COSMIC	20.411	Up-regulation
CK1_CK1_CK1-A_CSNK1A1_ST	P07900	HSP90AA1	P48729	CSNK1A1	S263	P256R	256	Missense	distal	-7	no	22.114	23.182	EPSD	COSMIC	20.411	Up-regulation
CK1_CK1_CK1-A_CSNK1A1_ST	P07900	HSP90AA1	P48729	CSNK1A1	T305	N300S	300	Missense	distal	-5	no	21.151	21.322	EPSD	COSMIC	20.411	Up-regulation
CK1_CK1_CK1-A_CSNK1A1_ST	P07900	HSP90AA1	P48729	CSNK1A1	S476	S470C	470	Missense	distal	-6	no	24.531	23.677	EPSD	COSMIC;CCLE	20.411	Down-regulation
CK1_CK1_CK1-A_CSNK1A1_ST	P07900	HSP90AA1	P48729	CSNK1A1	S476	C481G	481	Missense	distal	5	no	24.531	24.519	EPSD	COSMIC	20.411	Down-regulation
CK1_CK1_CK1-A_CSNK1A1_ST	P07900	HSP90AA1	P48729	CSNK1A1	S476	G471V	471	Missense	distal	-5	no	24.531	22.478	EPSD	COSMIC	20.411	Down-regulation
CK1_CK1_CK1-A_CSNK1A1_ST	P07900	HSP90AA1	P48729	CSNK1A1	S476	D472N	472	Missense	distal	-4	no	24.531	20.793	EPSD	COSMIC	20.411	Down-regulation
CK1_CK1_CK1-A_CSNK1A1_ST	P07900	HSP90AA1	P48729	CSNK1A1	S677	A670V	670	Missense	distal	-7	no	26.288	24.053	EPSD	COSMIC	20.411	Down-regulation
CK1_CK1_CK1-A_CSNK1A1_ST	P07900	HSP90AA1	P48729	CSNK1A1	S726	D724N	724	Missense	proximal	-2	no	21.702	19.577	PhosphoSitePlus;EPSD	COSMIC	20.411	Loss
CK1_CK1_CK1-A_CSNK1A1_ST	P07900	HSP90AA1	P48729	CSNK1A1	S726	E729K	729	Missense	distal	3	no	21.702	17.572	PhosphoSitePlus;EPSD	COSMIC	20.411	Loss
CK1_CK1_CK1-A_CSNK1A1_ST	P17181	IFNAR1	P48729	CSNK1A1	S532	S528T	528	Missense	distal	-4	no	21.791	20.156	EPSD	COSMIC	20.411	Loss
CK1_CK1_CK1-A_CSNK1A1_ST	P17181	IFNAR1	P48729	CSNK1A1	S532	S539Y	539	Missense	distal	7	no	21.791	22.044	EPSD	COSMIC	20.411	Up-regulation
CK1_CK1_CK1-A_CSNK1A1_ST	P01106	MYC	P48729	CSNK1A1	S67	P63S	63	Missense	distal	-4	no	17.928	20.620	EPSD;PhosphoSitePlus	COSMIC;CCLE	20.411	Gain
CK1_CK1_CK1-A_CSNK1A1_ST	P01106	MYC	P48729	CSNK1A1	S172	C171S	171	Missense	proximal	-1	no	19.884	21.064	EPSD	COSMIC	20.411	Gain
CK1_CK1_CK1-A_CSNK1A1_ST	P01106	MYC	P48729	CSNK1A1	S204	Y197D	197	Missense	distal	-7	no	19.291	21.020	EPSD	COSMIC	20.411	Gain
CK1_CK1_CK1-A_CSNK1A1_ST	P01106	MYC	P48729	CSNK1A1	S249	P246S	246	Missense	distal	-3	no	15.611	21.798	EPSD	COSMIC	20.411	Gain
CK1_CK1_CK1-A_CSNK1A1_ST	P01106	MYC	P48729	CSNK1A1	S250	P246S	246	Missense	distal	-4	no	19.593	22.285	EPSD	COSMIC	20.411	Gain
CK1_CK1_CK1-A_CSNK1A1_ST	P01106	MYC	P48729	CSNK1A1	S252	P245S	245	Missense	distal	-7	no	22.474	23.140	PhosphoSitePlus;EPSD	COSMIC	20.411	Up-regulation
CK1_CK1_CK1-A_CSNK1A1_ST	P01106	MYC	P48729	CSNK1A1	S252	E257G	257	Missense	distal	5	no	22.474	22.819	PhosphoSitePlus;EPSD	COSMIC	20.411	Up-regulation
CK1_CK1_CK1-A_CSNK1A1_ST	P01106	MYC	P48729	CSNK1A1	S252	D258N	258	Missense	distal	6	no	22.474	22.328	PhosphoSitePlus;EPSD	COSMIC	20.411	Down-regulation
CK1_CK1_CK1-A_CSNK1A1_ST	P01106	MYC	P48729	CSNK1A1	S252	E253K	253	Missense	proximal	1	no	22.474	22.014	PhosphoSitePlus;EPSD	COSMIC	20.411	Down-regulation
CK1_CK1_CK1-A_CSNK1A1_ST	P01106	MYC	P48729	CSNK1A1	S252	S249I	249	Missense	distal	-3	no	22.474	18.492	PhosphoSitePlus;EPSD	COSMIC	20.411	Loss
CK1_CK1_CK1-A_CSNK1A1_ST	P01106	MYC	P48729	CSNK1A1	S252	D251N	251	Missense	proximal	-1	no	22.474	21.910	PhosphoSitePlus;EPSD	COSMIC;CCLE	20.411	Down-regulation
CK1_CK1_CK1-A_CSNK1A1_ST	P01106	MYC	P48729	CSNK1A1	S252	E259K	259	Missense	distal	7	no	22.474	22.603	PhosphoSitePlus;EPSD	COSMIC	20.411	Up-regulation
CK1_CK1_CK1-A_CSNK1A1_ST	P01106	MYC	P48729	CSNK1A1	S252	P245A	245	Missense	distal	-7	no	22.474	23.662	PhosphoSitePlus;EPSD	COSMIC	20.411	Up-regulation
CK1_CK1_CK1-A_CSNK1A1_ST	P01106	MYC	P48729	CSNK1A1	S252	S252F	252	Missense	central	0	yes	22.474	0.000	PhosphoSitePlus;EPSD	COSMIC	20.411	Loss
CK1_CK1_CK1-A_CSNK1A1_ST	P01106	MYC	P48729	CSNK1A1	S252	S249N	249	Missense	distal	-3	no	22.474	17.565	PhosphoSitePlus;EPSD	COSMIC;CCLE	20.411	Loss
CK1_CK1_CK1-A_CSNK1A1_ST	P01106	MYC	P48729	CSNK1A1	S252	S249T	249	Missense	distal	-3	no	22.474	18.709	PhosphoSitePlus;EPSD	COSMIC	20.411	Loss
CK1_CK1_CK1-A_CSNK1A1_ST	P01106	MYC	P48729	CSNK1A1	S252	P245Q	245	Missense	distal	-7	no	22.474	23.227	PhosphoSitePlus;EPSD	COSMIC	20.411	Up-regulation
CK1_CK1_CK1-A_CSNK1A1_ST	P01106	MYC	P48729	CSNK1A1	S252	P246S	246	Missense	distal	-6	no	22.474	23.155	PhosphoSitePlus;EPSD	COSMIC	20.411	Up-regulation
CK1_CK1_CK1-A_CSNK1A1_ST	P01106	MYC	P48729	CSNK1A1	S252	S250I	250	Missense	proximal	-2	no	22.474	20.295	PhosphoSitePlus;EPSD	COSMIC	20.411	Loss
CK1_CK1_CK1-A_CSNK1A1_ST	P01106	MYC	P48729	CSNK1A1	S252	S250C	250	Missense	proximal	-2	no	22.474	21.157	PhosphoSitePlus;EPSD	COSMIC	20.411	Down-regulation
CK1_CK1_CK1-A_CSNK1A1_ST	P01106	MYC	P48729	CSNK1A1	S252	P246R	246	Missense	distal	-6	no	22.474	22.627	PhosphoSitePlus;EPSD	COSMIC	20.411	Up-regulation
CK1_CK1_CK1-A_CSNK1A1_ST	P01106	MYC	P48729	CSNK1A1	S252	D251E	251	Missense	proximal	-1	no	22.474	23.104	PhosphoSitePlus;EPSD	COSMIC	20.411	Up-regulation
CK1_CK1_CK1-A_CSNK1A1_ST	P01106	MYC	P48729	CSNK1A1	S252	P245L	245	Missense	distal	-7	no	22.474	22.459	PhosphoSitePlus;EPSD	COSMIC	20.411	Down-regulation
CK1_CK1_CK1-A_CSNK1A1_ST	P01106	MYC	P48729	CSNK1A1	S252	S250R	250	Missense	proximal	-2	no	22.474	21.384	PhosphoSitePlus;EPSD	COSMIC	20.411	Down-regulation
CK1_CK1_CK1-A_CSNK1A1_ST	P01106	MYC	P48729	CSNK1A1	S252	S252Y	252	Missense	central	0	yes	22.474	0.000	PhosphoSitePlus;EPSD	COSMIC	20.411	Loss
CK1_CK1_CK1-A_CSNK1A1_ST	P01106	MYC	P48729	CSNK1A1	S252	E257Q	257	Missense	distal	5	no	22.474	22.382	PhosphoSitePlus;EPSD	COSMIC	20.411	Down-regulation
CK1_CK1_CK1-A_CSNK1A1_ST	P01106	MYC	P48729	CSNK1A1	S252	E259G	259	Missense	distal	7	no	22.474	22.620	PhosphoSitePlus;EPSD	COSMIC	20.411	Up-regulation
CK1_CK1_CK1-A_CSNK1A1_ST	P01106	MYC	P48729	CSNK1A1	S252	T247I	247	Missense	distal	-5	no	22.474	22.933	PhosphoSitePlus;EPSD	COSMIC	20.411	Up-regulation
CK1_CK1_CK1-A_CSNK1A1_ST	P01106	MYC	P48729	CSNK1A1	S252	S249R	249	Missense	distal	-3	no	22.474	18.248	PhosphoSitePlus;EPSD	COSMIC;CCLE	20.411	Loss
CK1_CK1_CK1-A_CSNK1A1_ST	P01106	MYC	P48729	CSNK1A1	S281	S283F	283	Missense	proximal	2	no	24.160	23.138	EPSD	COSMIC	20.411	Down-regulation
CK1_CK1_CK1-A_CSNK1A1_ST	P01106	MYC	P48729	CSNK1A1	S281	S277L	277	Missense	distal	-4	no	24.160	20.353	EPSD	COSMIC	20.411	Loss
CK1_CK1_CK1-A_CSNK1A1_ST	P01106	MYC	P48729	CSNK1A1	S281	H287Q	287	Missense	distal	6	no	24.160	24.148	EPSD	COSMIC	20.411	Down-regulation
CK1_CK1_CK1-A_CSNK1A1_ST	P01106	MYC	P48729	CSNK1A1	S281	S279C	279	Missense	proximal	-2	no	24.160	22.843	EPSD	COSMIC	20.411	Down-regulation
CK1_CK1_CK1-A_CSNK1A1_ST	P01106	MYC	P48729	CSNK1A1	S281	S283Y	283	Missense	proximal	2	no	24.160	22.836	EPSD	COSMIC	20.411	Down-regulation
CK1_CK1_CK1-A_CSNK1A1_ST	P01106	MYC	P48729	CSNK1A1	S281	P282A	282	Missense	proximal	1	no	24.160	23.972	EPSD	COSMIC	20.411	Down-regulation
CK1_CK1_CK1-A_CSNK1A1_ST	P01106	MYC	P48729	CSNK1A1	S281	G285E	285	Missense	distal	4	no	24.160	24.236	EPSD	COSMIC	20.411	Up-regulation
CK1_CK1_CK1-A_CSNK1A1_ST	P01106	MYC	P48729	CSNK1A1	S281	G280R	280	Missense	proximal	-1	no	24.160	22.997	EPSD	COSMIC	20.411	Down-regulation
CK1_CK1_CK1-A_CSNK1A1_ST	P01106	MYC	P48729	CSNK1A1	S281	G274D	274	Missense	distal	-7	no	24.160	23.369	EPSD	COSMIC	20.411	Down-regulation
CK1_CK1_CK1-A_CSNK1A1_ST	P01106	MYC	P48729	CSNK1A1	S281	S281F	281	Missense	central	0	yes	24.160	0.000	EPSD	COSMIC	20.411	Loss
CK1_CK1_CK1-A_CSNK1A1_ST	P01106	MYC	P48729	CSNK1A1	S283	S283F	283	Missense	central	0	yes	25.043	0.000	EPSD	COSMIC	20.411	Loss
CK1_CK1_CK1-A_CSNK1A1_ST	P01106	MYC	P48729	CSNK1A1	S283	S277L	277	Missense	distal	-6	no	25.043	24.149	EPSD	COSMIC	20.411	Down-regulation
CK1_CK1_CK1-A_CSNK1A1_ST	P01106	MYC	P48729	CSNK1A1	S283	P290T	290	Missense	distal	7	no	25.043	24.915	EPSD	COSMIC	20.411	Down-regulation
CK1_CK1_CK1-A_CSNK1A1_ST	P01106	MYC	P48729	CSNK1A1	S283	H287Q	287	Missense	distal	4	no	25.043	25.077	EPSD	COSMIC	20.411	Up-regulation
CK1_CK1_CK1-A_CSNK1A1_ST	P01106	MYC	P48729	CSNK1A1	S283	S279C	279	Missense	distal	-4	no	25.043	22.344	EPSD	COSMIC	20.411	Down-regulation
CK1_CK1_CK1-A_CSNK1A1_ST	P01106	MYC	P48729	CSNK1A1	S283	S283Y	283	Missense	central	0	yes	25.043	0.000	EPSD	COSMIC	20.411	Loss
CK1_CK1_CK1-A_CSNK1A1_ST	P01106	MYC	P48729	CSNK1A1	S283	P282A	282	Missense	proximal	-1	no	25.043	24.903	EPSD	COSMIC	20.411	Down-regulation
CK1_CK1_CK1-A_CSNK1A1_ST	P01106	MYC	P48729	CSNK1A1	S283	G285E	285	Missense	proximal	2	no	25.043	24.648	EPSD	COSMIC	20.411	Down-regulation
CK1_CK1_CK1-A_CSNK1A1_ST	P01106	MYC	P48729	CSNK1A1	S283	P290H	290	Missense	distal	7	no	25.043	25.088	EPSD	COSMIC	20.411	Up-regulation
CK1_CK1_CK1-A_CSNK1A1_ST	P01106	MYC	P48729	CSNK1A1	S283	P290S	290	Missense	distal	7	no	25.043	24.855	EPSD	COSMIC	20.411	Down-regulation
CK1_CK1_CK1-A_CSNK1A1_ST	P01106	MYC	P48729	CSNK1A1	S283	G280R	280	Missense	distal	-3	no	25.043	22.508	EPSD	COSMIC	20.411	Down-regulation
CK1_CK1_CK1-A_CSNK1A1_ST	P01106	MYC	P48729	CSNK1A1	S283	S281F	281	Missense	proximal	-2	no	25.043	23.176	EPSD	COSMIC	20.411	Down-regulation
CK1_CK1_CK1-A_CSNK1A1_ST	P35222	CTNNB1	P48729	CSNK1A1	S29	V22I	22	Missense	distal	-7	no	18.542	20.594	EPSD	COSMIC	20.411	Gain
CK1_CK1_CK1-A_CSNK1A1_ST	P35222	CTNNB1	P48729	CSNK1A1	S29	V22A	22	Missense	distal	-7	no	18.542	20.778	EPSD	COSMIC	20.411	Gain
CK1_CK1_CK1-A_CSNK1A1_ST	P35222	CTNNB1	P48729	CSNK1A1	S29	V22G	22	Missense	distal	-7	no	18.542	21.307	EPSD	COSMIC	20.411	Gain
CK1_CK1_CK1-A_CSNK1A1_ST	P35222	CTNNB1	P48729	CSNK1A1	T41	P44S	44	Missense	distal	3	no	18.836	23.101	EPSD	COSMIC	20.411	Gain
CK1_CK1_CK1-A_CSNK1A1_ST	P35222	CTNNB1	P48729	CSNK1A1	T41	P44A	44	Missense	distal	3	no	18.836	20.871	EPSD	COSMIC	20.411	Gain
CK1_CK1_CK1-A_CSNK1A1_ST	P35222	CTNNB1	P48729	CSNK1A1	T41	G38D	38	Missense	distal	-3	no	18.836	20.898	EPSD	COSMIC	20.411	Gain
CK1_CK1_CK1-A_CSNK1A1_ST	P35222	CTNNB1	P48729	CSNK1A1	T41	G38S	38	Missense	distal	-3	no	18.836	20.527	EPSD	COSMIC	20.411	Gain
CK1_CK1_CK1-A_CSNK1A1_ST	P35222	CTNNB1	P48729	CSNK1A1	T41	P44I	44	Missense	distal	3	no	18.836	21.845	EPSD	COSMIC	20.411	Gain
CK1_CK1_CK1-A_CSNK1A1_ST	P35222	CTNNB1	P48729	CSNK1A1	S45	P44S	44	Missense	proximal	-1	no	22.310	22.302	PhosphoSitePlus	COSMIC	20.411	Down-regulation
CK1_CK1_CK1-A_CSNK1A1_ST	P35222	CTNNB1	P48729	CSNK1A1	S45	A43V	43	Missense	proximal	-2	no	22.310	20.913	PhosphoSitePlus	COSMIC	20.411	Down-regulation
CK1_CK1_CK1-A_CSNK1A1_ST	P35222	CTNNB1	P48729	CSNK1A1	S45	G48D	48	Missense	distal	3	no	22.310	22.584	PhosphoSitePlus	COSMIC	20.411	Up-regulation
CK1_CK1_CK1-A_CSNK1A1_ST	P35222	CTNNB1	P48729	CSNK1A1	S45	A39G	39	Missense	distal	-6	no	22.310	23.359	PhosphoSitePlus	COSMIC	20.411	Up-regulation
CK1_CK1_CK1-A_CSNK1A1_ST	P35222	CTNNB1	P48729	CSNK1A1	S45	N51T	51	Missense	distal	6	no	22.310	22.423	PhosphoSitePlus	COSMIC	20.411	Up-regulation
CK1_CK1_CK1-A_CSNK1A1_ST	P35222	CTNNB1	P48729	CSNK1A1	S45	P52L	52	Missense	distal	7	no	22.310	22.158	PhosphoSitePlus	COSMIC	20.411	Down-regulation
CK1_CK1_CK1-A_CSNK1A1_ST	P35222	CTNNB1	P48729	CSNK1A1	S45	N51S	51	Missense	distal	6	no	22.310	22.527	PhosphoSitePlus	COSMIC	20.411	Up-regulation
CK1_CK1_CK1-A_CSNK1A1_ST	P35222	CTNNB1	P48729	CSNK1A1	S45	G38A	38	Missense	distal	-7	no	22.310	21.781	PhosphoSitePlus	COSMIC	20.411	Down-regulation
CK1_CK1_CK1-A_CSNK1A1_ST	P35222	CTNNB1	P48729	CSNK1A1	S45	T40I	40	Missense	distal	-5	no	22.310	22.770	PhosphoSitePlus	COSMIC	20.411	Up-regulation
CK1_CK1_CK1-A_CSNK1A1_ST	P35222	CTNNB1	P48729	CSNK1A1	S45	P44A	44	Missense	proximal	-1	no	22.310	22.170	PhosphoSitePlus	COSMIC	20.411	Down-regulation
CK1_CK1_CK1-A_CSNK1A1_ST	P35222	CTNNB1	P48729	CSNK1A1	S45	T41P	41	Missense	distal	-4	no	22.310	21.253	PhosphoSitePlus	COSMIC	20.411	Down-regulation
CK1_CK1_CK1-A_CSNK1A1_ST	P35222	CTNNB1	P48729	CSNK1A1	S45	K49R	49	Missense	distal	4	no	22.310	22.423	PhosphoSitePlus	COSMIC	20.411	Up-regulation
CK1_CK1_CK1-A_CSNK1A1_ST	P35222	CTNNB1	P48729	CSNK1A1	S45	T42R	42	Missense	distal	-3	no	22.310	21.849	PhosphoSitePlus	COSMIC	20.411	Down-regulation
CK1_CK1_CK1-A_CSNK1A1_ST	P35222	CTNNB1	P48729	CSNK1A1	S45	S45A	45	Missense	central	0	yes	22.310	0.000	PhosphoSitePlus	COSMIC	20.411	Loss
CK1_CK1_CK1-A_CSNK1A1_ST	P35222	CTNNB1	P48729	CSNK1A1	S45	G48S	48	Missense	distal	3	no	22.310	21.862	PhosphoSitePlus	COSMIC	20.411	Down-regulation
CK1_CK1_CK1-A_CSNK1A1_ST	P35222	CTNNB1	P48729	CSNK1A1	S45	T40A	40	Missense	distal	-5	no	22.310	21.630	PhosphoSitePlus	COSMIC	20.411	Down-regulation
CK1_CK1_CK1-A_CSNK1A1_ST	P35222	CTNNB1	P48729	CSNK1A1	S45	A43T	43	Missense	proximal	-2	no	22.310	22.137	PhosphoSitePlus	COSMIC	20.411	Down-regulation
CK1_CK1_CK1-A_CSNK1A1_ST	P35222	CTNNB1	P48729	CSNK1A1	S45	P44L	44	Missense	proximal	-1	no	22.310	22.026	PhosphoSitePlus	COSMIC	20.411	Down-regulation
CK1_CK1_CK1-A_CSNK1A1_ST	P35222	CTNNB1	P48729	CSNK1A1	S45	T42I	42	Missense	distal	-3	no	22.310	22.093	PhosphoSitePlus	COSMIC	20.411	Down-regulation
CK1_CK1_CK1-A_CSNK1A1_ST	P35222	CTNNB1	P48729	CSNK1A1	S45	T42S	42	Missense	distal	-3	no	22.310	26.075	PhosphoSitePlus	COSMIC	20.411	Up-regulation
CK1_CK1_CK1-A_CSNK1A1_ST	P35222	CTNNB1	P48729	CSNK1A1	S45	T42K	42	Missense	distal	-3	no	22.310	20.050	PhosphoSitePlus	COSMIC	20.411	Loss
CK1_CK1_CK1-A_CSNK1A1_ST	P35222	CTNNB1	P48729	CSNK1A1	S45	S47G	47	Missense	proximal	2	no	22.310	22.656	PhosphoSitePlus	COSMIC	20.411	Up-regulation
CK1_CK1_CK1-A_CSNK1A1_ST	P35222	CTNNB1	P48729	CSNK1A1	S45	G48V	48	Missense	distal	3	no	22.310	19.277	PhosphoSitePlus	COSMIC	20.411	Loss
CK1_CK1_CK1-A_CSNK1A1_ST	P35222	CTNNB1	P48729	CSNK1A1	S45	S47N	47	Missense	proximal	2	no	22.310	21.259	PhosphoSitePlus	COSMIC	20.411	Down-regulation
CK1_CK1_CK1-A_CSNK1A1_ST	P35222	CTNNB1	P48729	CSNK1A1	S45	A39T	39	Missense	distal	-6	no	22.310	22.837	PhosphoSitePlus	COSMIC	20.411	Up-regulation
CK1_CK1_CK1-A_CSNK1A1_ST	P35222	CTNNB1	P48729	CSNK1A1	S45	K49T	49	Missense	distal	4	no	22.310	22.359	PhosphoSitePlus	COSMIC	20.411	Up-regulation
CK1_CK1_CK1-A_CSNK1A1_ST	P35222	CTNNB1	P48729	CSNK1A1	S45	G50D	50	Missense	distal	5	no	22.310	22.173	PhosphoSitePlus	COSMIC	20.411	Down-regulation
CK1_CK1_CK1-A_CSNK1A1_ST	P35222	CTNNB1	P48729	CSNK1A1	S45	A43P	43	Missense	proximal	-2	no	22.310	21.399	PhosphoSitePlus	COSMIC	20.411	Down-regulation
CK1_CK1_CK1-A_CSNK1A1_ST	P35222	CTNNB1	P48729	CSNK1A1	S45	L46P	46	Missense	proximal	1	no	22.310	22.200	PhosphoSitePlus	COSMIC	20.411	Down-regulation
CK1_CK1_CK1-A_CSNK1A1_ST	P35222	CTNNB1	P48729	CSNK1A1	S45	G38P	38	Missense	distal	-7	no	22.310	20.592	PhosphoSitePlus	COSMIC	20.411	Down-regulation
CK1_CK1_CK1-A_CSNK1A1_ST	P35222	CTNNB1	P48729	CSNK1A1	S45	G38D	38	Missense	distal	-7	no	22.310	21.518	PhosphoSitePlus	COSMIC	20.411	Down-regulation
CK1_CK1_CK1-A_CSNK1A1_ST	P35222	CTNNB1	P48729	CSNK1A1	S45	T42A	42	Missense	distal	-3	no	22.310	21.619	PhosphoSitePlus	COSMIC	20.411	Down-regulation
CK1_CK1_CK1-A_CSNK1A1_ST	P35222	CTNNB1	P48729	CSNK1A1	S45	L46V	46	Missense	proximal	1	no	22.310	22.034	PhosphoSitePlus	COSMIC	20.411	Down-regulation
CK1_CK1_CK1-A_CSNK1A1_ST	P35222	CTNNB1	P48729	CSNK1A1	S45	S47L	47	Missense	proximal	2	no	22.310	21.325	PhosphoSitePlus	COSMIC	20.411	Down-regulation
CK1_CK1_CK1-A_CSNK1A1_ST	P35222	CTNNB1	P48729	CSNK1A1	S45	T40S	40	Missense	distal	-5	no	22.310	22.942	PhosphoSitePlus	COSMIC	20.411	Up-regulation
CK1_CK1_CK1-A_CSNK1A1_ST	P35222	CTNNB1	P48729	CSNK1A1	S45	K49L	49	Missense	distal	4	no	22.310	22.424	PhosphoSitePlus	COSMIC	20.411	Up-regulation
CK1_CK1_CK1-A_CSNK1A1_ST	P35222	CTNNB1	P48729	CSNK1A1	S45	L46M	46	Missense	proximal	1	no	22.310	21.990	PhosphoSitePlus	COSMIC	20.411	Down-regulation
CK1_CK1_CK1-A_CSNK1A1_ST	P35222	CTNNB1	P48729	CSNK1A1	S45	S47T	47	Missense	proximal	2	no	22.310	21.518	PhosphoSitePlus	COSMIC	20.411	Down-regulation
CK1_CK1_CK1-A_CSNK1A1_ST	P35222	CTNNB1	P48729	CSNK1A1	S45	T41S	41	Missense	distal	-4	no	22.310	23.945	PhosphoSitePlus	COSMIC	20.411	Up-regulation
CK1_CK1_CK1-A_CSNK1A1_ST	P35222	CTNNB1	P48729	CSNK1A1	S45	T42Q	42	Missense	distal	-3	no	22.310	22.804	PhosphoSitePlus	COSMIC	20.411	Up-regulation
CK1_CK1_CK1-A_CSNK1A1_ST	P35222	CTNNB1	P48729	CSNK1A1	S45	S47C	47	Missense	proximal	2	no	22.310	21.325	PhosphoSitePlus	COSMIC	20.411	Down-regulation
CK1_CK1_CK1-A_CSNK1A1_ST	P35222	CTNNB1	P48729	CSNK1A1	S45	K49E	49	Missense	distal	4	no	22.310	22.500	PhosphoSitePlus	COSMIC	20.411	Up-regulation
CK1_CK1_CK1-A_CSNK1A1_ST	P35222	CTNNB1	P48729	CSNK1A1	S45	S47R	47	Missense	proximal	2	no	22.310	21.704	PhosphoSitePlus	COSMIC	20.411	Down-regulation
CK1_CK1_CK1-A_CSNK1A1_ST	P35222	CTNNB1	P48729	CSNK1A1	S45	A39V	39	Missense	distal	-6	no	22.310	22.052	PhosphoSitePlus	COSMIC	20.411	Down-regulation
CK1_CK1_CK1-A_CSNK1A1_ST	P35222	CTNNB1	P48729	CSNK1A1	S45	S45E	45	Missense	central	0	yes	22.310	0.000	PhosphoSitePlus	COSMIC	20.411	Loss
CK1_CK1_CK1-A_CSNK1A1_ST	P35222	CTNNB1	P48729	CSNK1A1	S45	G50S	50	Missense	distal	5	no	22.310	21.999	PhosphoSitePlus	COSMIC	20.411	Down-regulation
CK1_CK1_CK1-A_CSNK1A1_ST	P35222	CTNNB1	P48729	CSNK1A1	S45	S45N	45	Missense	central	0	yes	22.310	0.000	PhosphoSitePlus	COSMIC	20.411	Loss
CK1_CK1_CK1-A_CSNK1A1_ST	P35222	CTNNB1	P48729	CSNK1A1	S45	G38X	38	Missense	distal	-7	no	22.310	20.897	PhosphoSitePlus	COSMIC	20.411	Down-regulation
CK1_CK1_CK1-A_CSNK1A1_ST	P35222	CTNNB1	P48729	CSNK1A1	S45	L46Q	46	Missense	proximal	1	no	22.310	22.334	PhosphoSitePlus	COSMIC	20.411	Up-regulation
CK1_CK1_CK1-A_CSNK1A1_ST	P35222	CTNNB1	P48729	CSNK1A1	S45	S45X	45	Missense	central	0	yes	22.310	0.000	PhosphoSitePlus	COSMIC	20.411	Loss
CK1_CK1_CK1-A_CSNK1A1_ST	P35222	CTNNB1	P48729	CSNK1A1	S45	G38S	38	Missense	distal	-7	no	22.310	21.258	PhosphoSitePlus	COSMIC	20.411	Down-regulation
CK1_CK1_CK1-A_CSNK1A1_ST	P35222	CTNNB1	P48729	CSNK1A1	S45	P44I	44	Missense	proximal	-1	no	22.310	23.059	PhosphoSitePlus	COSMIC	20.411	Up-regulation
CK1_CK1_CK1-A_CSNK1A1_ST	P35222	CTNNB1	P48729	CSNK1A1	S45	S47I	47	Missense	proximal	2	no	22.310	21.512	PhosphoSitePlus	COSMIC	20.411	Down-regulation
CK1_CK1_CK1-A_CSNK1A1_ST	P35222	CTNNB1	P48729	CSNK1A1	S45	S47Y	47	Missense	proximal	2	no	22.310	20.985	PhosphoSitePlus	COSMIC	20.411	Down-regulation
CK1_CK1_CK1-A_CSNK1A1_ST	P35222	CTNNB1	P48729	CSNK1A1	S45	T40P	40	Missense	distal	-5	no	22.310	22.509	PhosphoSitePlus	COSMIC	20.411	Up-regulation
CK1_CK1_CK1-A_CSNK1A1_ST	P35222	CTNNB1	P48729	CSNK1A1	S47	P44S	44	Missense	distal	-3	no	18.636	24.824	EPSD	COSMIC	20.411	Gain
CK1_CK1_CK1-A_CSNK1A1_ST	P35222	CTNNB1	P48729	CSNK1A1	S47	P44I	44	Missense	distal	-3	no	18.636	20.842	EPSD	COSMIC	20.411	Gain
CK1_CK1_CK1-A_CSNK1A1_ST	P35222	CTNNB1	P48729	CSNK1A1	T393	K394N	394	Missense	proximal	1	no	20.357	20.459	EPSD	COSMIC	20.411	Gain
CK1_CK1_CK1-A_CSNK1A1_ST	P35222	CTNNB1	P48729	CSNK1A1	S552	T551K	551	Missense	proximal	-1	no	20.527	20.339	EPSD	COSMIC	20.411	Loss
CK1_CK1_CK1-A_CSNK1A1_ST	P35222	CTNNB1	P48729	CSNK1A1	S552	R549C	549	Missense	distal	-3	no	20.527	20.421	EPSD	COSMIC	20.411	Down-regulation
CK1_CK1_CK1-A_CSNK1A1_ST	P35222	CTNNB1	P48729	CSNK1A1	S552	Q545K	545	Missense	distal	-7	no	20.527	21.223	EPSD	COSMIC	20.411	Up-regulation
CK1_CK1_CK1-A_CSNK1A1_ST	P35222	CTNNB1	P48729	CSNK1A1	S552	Q558H	558	Missense	distal	6	no	20.527	20.540	EPSD	COSMIC	20.411	Up-regulation
CK1_CK1_CK1-A_CSNK1A1_ST	P35222	CTNNB1	P48729	CSNK1A1	S552	G555A	555	Missense	distal	3	no	20.527	17.849	EPSD	COSMIC	20.411	Loss
CK1_CK1_CK1-A_CSNK1A1_ST	P35222	CTNNB1	P48729	CSNK1A1	S552	R550H	550	Missense	proximal	-2	no	20.527	18.906	EPSD	COSMIC	20.411	Loss
CK1_CK1_CK1-A_CSNK1A1_ST	P35222	CTNNB1	P48729	CSNK1A1	S552	R550L	550	Missense	proximal	-2	no	20.527	18.764	EPSD	COSMIC	20.411	Loss
CK1_CK1_CK1-A_CSNK1A1_ST	P35222	CTNNB1	P48729	CSNK1A1	S552	D546E	546	Missense	distal	-6	no	20.527	19.591	EPSD	COSMIC	20.411	Loss
CK1_CK1_CK1-A_CSNK1A1_ST	P35222	CTNNB1	P48729	CSNK1A1	S552	S552F	552	Missense	central	0	yes	20.527	0.000	EPSD	COSMIC	20.411	Loss
CK1_CK1_CK1-A_CSNK1A1_ST	P35222	CTNNB1	P48729	CSNK1A1	S552	T547S	547	Missense	distal	-5	no	20.527	21.159	EPSD	COSMIC	20.411	Up-regulation
CK1_CK1_CK1-A_CSNK1A1_ST	P35222	CTNNB1	P48729	CSNK1A1	S552	G554D	554	Missense	proximal	2	no	20.527	20.323	EPSD	COSMIC	20.411	Loss
CK1_CK1_CK1-A_CSNK1A1_ST	P35222	CTNNB1	P48729	CSNK1A1	S552	R550Q	550	Missense	proximal	-2	no	20.527	21.034	EPSD	COSMIC	20.411	Up-regulation
CK1_CK1_CK1-A_CSNK1A1_ST	P35222	CTNNB1	P48729	CSNK1A1	S552	T551I	551	Missense	proximal	-1	no	20.527	21.682	EPSD	COSMIC	20.411	Up-regulation
CK1_CK1_CK1-A_CSNK1A1_ST	P35222	CTNNB1	P48729	CSNK1A1	S680	E677D	677	Missense	distal	-3	no	18.304	20.779	EPSD	COSMIC	20.411	Gain
CK1_CK1_CK1-A_CSNK1A1_ST	P35222	CTNNB1	P48729	CSNK1A1	S715	Y716C	716	Missense	proximal	1	no	24.180	24.044	EPSD	COSMIC	20.411	Down-regulation
CK1_CK1_CK1-A_CSNK1A1_ST	P35222	CTNNB1	P48729	CSNK1A1	S715	H720P	720	Missense	distal	5	no	24.180	23.954	EPSD	COSMIC	20.411	Down-regulation
CK1_CK1_CK1-A_CSNK1A1_ST	P35222	CTNNB1	P48729	CSNK1A1	S715	R717C	717	Missense	proximal	2	no	24.180	23.801	EPSD	COSMIC	20.411	Down-regulation
CK1_CK1_CK1-A_CSNK1A1_ST	P35222	CTNNB1	P48729	CSNK1A1	S715	S715R	715	Missense	central	0	yes	24.180	0.000	EPSD	COSMIC	20.411	Loss
CK1_CK1_CK1-A_CSNK1A1_ST	P35222	CTNNB1	P48729	CSNK1A1	S715	D712N	712	Missense	distal	-3	no	24.180	18.900	EPSD	COSMIC	20.411	Loss
CK1_CK1_CK1-A_CSNK1A1_ST	P35222	CTNNB1	P48729	CSNK1A1	S715	P714S	714	Missense	proximal	-1	no	24.180	24.171	EPSD	COSMIC	20.411	Down-regulation
CK1_CK1_CK1-A_CSNK1A1_ST	P35222	CTNNB1	P48729	CSNK1A1	S715	Y709C	709	Missense	distal	-6	no	24.180	24.374	EPSD	COSMIC	20.411	Up-regulation
CK1_CK1_CK1-A_CSNK1A1_ST	P35222	CTNNB1	P48729	CSNK1A1	S715	R710C	710	Missense	distal	-5	no	24.180	23.746	EPSD	COSMIC	20.411	Down-regulation
CK1_CK1_CK1-A_CSNK1A1_ST	P35222	CTNNB1	P48729	CSNK1A1	S718	Y716C	716	Missense	proximal	-2	no	24.815	25.540	EPSD	COSMIC	20.411	Up-regulation
CK1_CK1_CK1-A_CSNK1A1_ST	P35222	CTNNB1	P48729	CSNK1A1	S718	H720P	720	Missense	proximal	2	no	24.815	25.132	EPSD	COSMIC	20.411	Up-regulation
CK1_CK1_CK1-A_CSNK1A1_ST	P35222	CTNNB1	P48729	CSNK1A1	S718	R717C	717	Missense	proximal	-1	no	24.815	24.100	EPSD	COSMIC	20.411	Down-regulation
CK1_CK1_CK1-A_CSNK1A1_ST	P35222	CTNNB1	P48729	CSNK1A1	S718	S715R	715	Missense	distal	-3	no	24.815	20.589	EPSD	COSMIC	20.411	Down-regulation
CK1_CK1_CK1-A_CSNK1A1_ST	P35222	CTNNB1	P48729	CSNK1A1	S718	D712N	712	Missense	distal	-6	no	24.815	23.535	EPSD	COSMIC	20.411	Down-regulation
CK1_CK1_CK1-A_CSNK1A1_ST	P35222	CTNNB1	P48729	CSNK1A1	S718	P714S	714	Missense	distal	-4	no	24.815	27.507	EPSD	COSMIC	20.411	Up-regulation
CK1_CK1_CK1-A_CSNK1A1_ST	P35222	CTNNB1	P48729	CSNK1A1	S718	Y724S	724	Missense	distal	6	no	24.815	25.391	EPSD	COSMIC	20.411	Up-regulation
CK1_CK1_CK1-A_CSNK1A1_ST	P35222	CTNNB1	P48729	CSNK1A1	S718	G723S	723	Missense	distal	5	no	24.815	24.504	EPSD	COSMIC	20.411	Down-regulation
CK1_CK1_CK1-A_CSNK1A1_ST	P35222	CTNNB1	P48729	CSNK1A1	S718	Y724C	724	Missense	distal	6	no	24.815	24.966	EPSD	COSMIC	20.411	Up-regulation
CK1_CK1_CK1-A_CSNK1A1_ST	P35222	CTNNB1	P48729	CSNK1A1	S718	G725D	725	Missense	distal	7	no	24.815	24.755	EPSD	COSMIC	20.411	Down-regulation
CK1_CK1_CK1-A_CSNK1A1_ST	Q9H6E5	TUT1	P48729	CSNK1A1	S115	R120H	120	Missense	distal	5	no	22.193	22.257	EPSD	COSMIC	20.411	Up-regulation
CK1_CK1_CK1-A_CSNK1A1_ST	Q9H6E5	TUT1	P48729	CSNK1A1	S136	P134R	134	Missense	proximal	-2	no	20.040	20.820	EPSD	COSMIC	20.411	Gain
CK1_CK1_CK1-A_CSNK1A1_ST	Q9H6E5	TUT1	P48729	CSNK1A1	S383	R387Q	387	Missense	distal	4	no	22.086	21.988	EPSD	COSMIC	20.411	Down-regulation
CK1_CK1_CK1-A_CSNK1A1_ST	Q9H6E5	TUT1	P48729	CSNK1A1	S383	L378F	378	Missense	distal	-5	no	22.086	20.815	EPSD	COSMIC	20.411	Down-regulation
CK1_CK1_CK1-A_CSNK1A1_ST	Q9H6E5	TUT1	P48729	CSNK1A1	S383	G377C	377	Missense	distal	-6	no	22.086	21.093	EPSD	COSMIC	20.411	Down-regulation
CK1_CK1_CK1-A_CSNK1A1_ST	Q9H6E5	TUT1	P48729	CSNK1A1	S513	L507F	507	Missense	distal	-6	no	23.746	23.427	EPSD	COSMIC	20.411	Down-regulation
CK1_CK1_CK1-A_CSNK1A1_ST	Q9H6E5	TUT1	P48729	CSNK1A1	S658	D664A	664	Missense	distal	6	no	21.021	20.733	EPSD	COSMIC	20.411	Down-regulation
CK1_CK1_CK1-A_CSNK1A1_ST	Q9H6E5	TUT1	P48729	CSNK1A1	S731	R738G	738	Missense	distal	7	no	21.360	21.274	EPSD	COSMIC	20.411	Down-regulation
CK1_CK1_CK1-A_CSNK1A1_ST	Q9H6E5	TUT1	P48729	CSNK1A1	S731	H732D	732	Missense	proximal	1	no	21.360	21.674	EPSD	COSMIC	20.411	Up-regulation
CK1_CK1_CK1-A_CSNK1A1_ST	Q9H6E5	TUT1	P48729	CSNK1A1	S750	E744Q	744	Missense	distal	-6	no	27.025	27.355	EPSD	COSMIC	20.411	Up-regulation
CK1_CK1_CK1-A_CSNK1A1_ST	Q9H6E5	TUT1	P48729	CSNK1A1	S750	A754E	754	Missense	distal	4	no	27.025	27.154	EPSD	COSMIC	20.411	Up-regulation
CK1_CK1_CK1-A_CSNK1A1_ST	P63104	YWHAZ	P48729	CSNK1A1	S37	Q32H	32	Missense	distal	-5	no	23.184	21.888	EPSD	COSMIC	20.411	Down-regulation
CK1_CK1_CK1-A_CSNK1A1_ST	P63104	YWHAZ	P48729	CSNK1A1	S37	N38S	38	Missense	proximal	1	no	23.184	23.240	EPSD	COSMIC	20.411	Up-regulation
CK1_CK1_CK1-A_CSNK1A1_ST	P63104	YWHAZ	P48729	CSNK1A1	S37	N38K	38	Missense	proximal	1	no	23.184	23.082	EPSD	COSMIC	20.411	Down-regulation
CK1_CK1_CK1-A_CSNK1A1_ST	P63104	YWHAZ	P48729	CSNK1A1	S37	E31Q	31	Missense	distal	-6	no	23.184	23.514	EPSD	COSMIC	20.411	Up-regulation
CK1_CK1_CK1-A_CSNK1A1_ST	P56537	EIF6	P48729	CSNK1A1	S174	P180L	180	Missense	distal	6	no	25.943	26.029	EPSD;PhosphoSitePlus	COSMIC	20.411	Up-regulation
CK1_CK1_CK1-A_CSNK1A1_ST	P56537	EIF6	P48729	CSNK1A1	S174	S175F	175	Missense	proximal	1	no	25.943	25.886	EPSD;PhosphoSitePlus	COSMIC	20.411	Down-regulation
CK1_CK1_CK1-A_CSNK1A1_ST	P56537	EIF6	P48729	CSNK1A1	S175	P180L	180	Missense	distal	5	no	25.296	25.361	PhosphoSitePlus;EPSD	COSMIC	20.411	Up-regulation
CK1_CK1_CK1-A_CSNK1A1_ST	P56537	EIF6	P48729	CSNK1A1	S175	S175F	175	Missense	central	0	yes	25.296	0.000	PhosphoSitePlus;EPSD	COSMIC	20.411	Loss
CK1_CK1_CK1-A_CSNK1A1_ST	P67809	YBX1	P48729	CSNK1A1	S176	P178S	178	Missense	proximal	2	no	22.471	23.486	PhosphoSitePlus	COSMIC	20.411	Up-regulation
CK1_CK1_CK1-A_CSNK1A1_ST	P67809	YBX1	P48729	CSNK1A1	S176	E172K	172	Missense	distal	-4	no	22.471	18.774	PhosphoSitePlus	COSMIC	20.411	Loss
CK1_CK1_CK1-A_CSNK1A1_ST	P67809	YBX1	P48729	CSNK1A1	S176	S174L	174	Missense	proximal	-2	no	22.471	19.617	PhosphoSitePlus	COSMIC	20.411	Loss
CK1_CK1_CK1-A_CSNK1A1_ST	P67809	YBX1	P48729	CSNK1A1	S176	E179K	179	Missense	distal	3	no	22.471	18.341	PhosphoSitePlus	COSMIC	20.411	Loss
CK1_CK1_CK1-A_CSNK1A1_ST	P42892	ECE1	P48729	CSNK1A1	S34	D27V	27	Missense	distal	-7	no	22.472	20.499	EPSD;PhosphoSitePlus	COSMIC	20.411	Down-regulation
CK1_CK1_CK1-A_CSNK1A1_ST	P42892	ECE1	P48729	CSNK1A1	S34	A40V	40	Missense	distal	6	no	22.472	22.370	EPSD;PhosphoSitePlus	COSMIC	20.411	Down-regulation
CK1_CK1_CK1-A_CSNK1A1_ST	P42892	ECE1	P48729	CSNK1A1	S34	D39N	39	Missense	distal	5	no	22.472	22.718	EPSD;PhosphoSitePlus	COSMIC	20.411	Up-regulation
CK1_CK1_CK1-A_CSNK1A1_ST	P42892	ECE1	P48729	CSNK1A1	S34	V32M	32	Missense	proximal	-2	no	22.472	23.559	EPSD;PhosphoSitePlus	COSMIC	20.411	Up-regulation
CK1_CK1_CK1-A_CSNK1A1_ST	P42892	ECE1	P48729	CSNK1A1	S34	E28D	28	Missense	distal	-6	no	22.472	23.408	EPSD;PhosphoSitePlus	COSMIC	20.411	Up-regulation
CK1_CK1_CK1-A_CSNK1A1_ST	P42892	ECE1	P48729	CSNK1A1	S36	N43K	43	Missense	distal	7	no	23.841	23.799	PhosphoSitePlus;EPSD	COSMIC	20.411	Down-regulation
CK1_CK1_CK1-A_CSNK1A1_ST	P42892	ECE1	P48729	CSNK1A1	S36	A40V	40	Missense	distal	4	no	23.841	23.770	PhosphoSitePlus;EPSD	COSMIC	20.411	Down-regulation
CK1_CK1_CK1-A_CSNK1A1_ST	P42892	ECE1	P48729	CSNK1A1	S36	D39N	39	Missense	distal	3	no	23.841	20.641	PhosphoSitePlus;EPSD	COSMIC	20.411	Down-regulation
CK1_CK1_CK1-A_CSNK1A1_ST	P42892	ECE1	P48729	CSNK1A1	S36	V32M	32	Missense	distal	-4	no	23.841	24.156	PhosphoSitePlus;EPSD	COSMIC	20.411	Up-regulation
CK1_CK1_CK1-A_CSNK1A1_ST	P42892	ECE1	P48729	CSNK1A1	S633	R640H	640	Missense	distal	7	no	24.459	24.585	EPSD	COSMIC	20.411	Up-regulation
CK1_CK1_CK1-A_CSNK1A1_ST	P42892	ECE1	P48729	CSNK1A1	S633	R627L	627	Missense	distal	-6	no	24.459	24.093	EPSD	COSMIC	20.411	Down-regulation
CK1_CK1_CK1-A_CSNK1A1_ST	P42892	ECE1	P48729	CSNK1A1	S633	P628T	628	Missense	distal	-5	no	24.459	24.260	EPSD	COSMIC;CCLE	20.411	Down-regulation
CK1_CK1_CK1-A_CSNK1A1_ST	O60341	KDM1A	P48729	CSNK1A1	S31	S35F	35	Missense	distal	4	no	22.193	22.106	EPSD	COSMIC	20.411	Down-regulation
CK1_CK1_CK1-A_CSNK1A1_ST	O60341	KDM1A	P48729	CSNK1A1	S299	R295Q	295	Missense	distal	-4	no	19.393	21.607	EPSD	COSMIC	20.411	Gain
CK1_CK1_CK1-A_CSNK1A1_ST	O60341	KDM1A	P48729	CSNK1A1	S687	T684M	684	Missense	distal	-3	no	19.659	21.168	PhosphoSitePlus	COSMIC	20.411	Gain
CK1_CK1_CK1-A_CSNK1A1_ST	P78362	SRPK2	P48729	CSNK1A1	S472	L471I	471	Missense	proximal	-1	no	21.028	22.060	EPSD	COSMIC	20.411	Up-regulation
CK1_CK1_CK1-A_CSNK1A1_ST	P78362	SRPK2	P48729	CSNK1A1	S497	T498A	498	Missense	proximal	1	no	22.959	22.914	PhosphoSitePlus	COSMIC	20.411	Down-regulation
CK1_CK1_CK1-A_CSNK1A1_ST	P78362	SRPK2	P48729	CSNK1A1	S497	S497R	497	Missense	central	0	yes	22.959	0.000	PhosphoSitePlus	COSMIC	20.411	Loss
CK1_CK1_CK1-A_CSNK1A1_ST	O94916	NFAT5	P48729	CSNK1A1	S158	E162V	162	Missense	distal	4	no	25.501	25.302	PhosphoSitePlus	COSMIC	20.411	Down-regulation
CK1_CK1_CK1-A_CSNK1A1_ST	O94916	NFAT5	P48729	CSNK1A1	S158	R156Q	156	Missense	proximal	-2	no	25.501	26.008	PhosphoSitePlus	COSMIC	20.411	Up-regulation
CK1_CK1_CK1-A_CSNK1A1_ST	O94916	NFAT5	P48729	CSNK1A1	S220	R214Q	214	Missense	distal	-6	no	22.918	23.106	EPSD	COSMIC	20.411	Up-regulation
CK1_CK1_CK1-A_CSNK1A1_ST	O94916	NFAT5	P48729	CSNK1A1	S220	S220C	220	Missense	central	0	yes	22.918	0.000	EPSD	COSMIC	20.411	Loss
CK1_CK1_CK1-A_CSNK1A1_ST	O94916	NFAT5	P48729	CSNK1A1	S220	A227T	227	Missense	distal	7	no	22.918	22.898	EPSD	COSMIC	20.411	Down-regulation
CK1_CK1_CK1-A_CSNK1A1_ST	O94916	NFAT5	P48729	CSNK1A1	S301	R302H	302	Missense	proximal	1	no	22.571	22.485	EPSD	COSMIC	20.411	Down-regulation
CK1_CK1_CK1-A_CSNK1A1_ST	O94916	NFAT5	P48729	CSNK1A1	S301	R308K	308	Missense	distal	7	no	22.571	22.468	EPSD	COSMIC	20.411	Down-regulation
CK1_CK1_CK1-A_CSNK1A1_ST	O94916	NFAT5	P48729	CSNK1A1	S301	R295W	295	Missense	distal	-6	no	22.571	22.431	EPSD	COSMIC	20.411	Down-regulation
CK1_CK1_CK1-A_CSNK1A1_ST	O94916	NFAT5	P48729	CSNK1A1	S301	A294T	294	Missense	distal	-7	no	22.571	21.599	EPSD	COSMIC	20.411	Down-regulation
CK1_CK1_CK1-A_CSNK1A1_ST	O94916	NFAT5	P48729	CSNK1A1	S301	S304A	304	Missense	distal	3	no	22.571	20.341	EPSD	COSMIC	20.411	Loss
CK1_CK1_CK1-A_CSNK1A1_ST	O94916	NFAT5	P48729	CSNK1A1	S301	S304L	304	Missense	distal	3	no	22.571	18.819	EPSD	COSMIC	20.411	Loss
CK1_CK1_CK1-A_CSNK1A1_ST	O94916	NFAT5	P48729	CSNK1A1	S301	R308I	308	Missense	distal	7	no	22.571	22.374	EPSD	COSMIC	20.411	Down-regulation
CK1_CK1_CK1-A_CSNK1A1_ST	O94916	NFAT5	P48729	CSNK1A1	S301	V305L	305	Missense	distal	4	no	22.571	22.696	EPSD	COSMIC	20.411	Up-regulation
CK1_CK1_CK1-A_CSNK1A1_ST	O94916	NFAT5	P48729	CSNK1A1	S618	A614E	614	Missense	distal	-4	no	18.328	20.487	EPSD	COSMIC	20.411	Gain
CK1_CK1_CK1-A_CSNK1A1_ST	O94916	NFAT5	P48729	CSNK1A1	S1247	N1244D	1244	Missense	distal	-3	no	17.303	22.583	EPSD	COSMIC	20.411	Gain
CK1_CK1_CK1-A_CSNK1A1_ST	O14503	BHLHE40	P48729	CSNK1A1	S235	A228G	228	Missense	distal	-7	no	23.462	23.992	EPSD	COSMIC	20.411	Up-regulation
CK1_CK1_CK1-A_CSNK1A1_ST	O14503	BHLHE40	P48729	CSNK1A1	S235	S230P	230	Missense	distal	-5	no	23.462	23.030	EPSD	COSMIC	20.411	Down-regulation
CK1_CK1_CK1-A_CSNK1A1_ST	O14503	BHLHE40	P48729	CSNK1A1	S235	G232E	232	Missense	distal	-3	no	23.462	23.049	EPSD	COSMIC	20.411	Down-regulation
CK1_CK1_CK1-A_CSNK1A1_ST	O14503	BHLHE40	P48729	CSNK1A1	S237	S230P	230	Missense	distal	-7	no	24.300	23.634	EPSD	COSMIC	20.411	Down-regulation
CK1_CK1_CK1-A_CSNK1A1_ST	O14503	BHLHE40	P48729	CSNK1A1	S237	G232E	232	Missense	distal	-5	no	24.300	23.365	EPSD	COSMIC	20.411	Down-regulation
CK1_CK1_CK1-A_CSNK1A1_ST	O14503	BHLHE40	P48729	CSNK1A1	T239	G232E	232	Missense	distal	-7	no	20.851	20.344	EPSD	COSMIC	20.411	Loss
CK1_CK1_CK1-A_CSNK1A1_ST	O14503	BHLHE40	P48729	CSNK1A1	S249	D253N	253	Missense	distal	4	no	22.703	22.590	EPSD	COSMIC	20.411	Down-regulation
CK1_CK1_CK1-A_CSNK1A1_ST	P37840	SNCA	P48729	CSNK1A1	S87	V82G	82	Missense	distal	-5	no	21.035	23.088	PhosphoSitePlus;EPSD	COSMIC	20.411	Up-regulation
TKL_RIPK_RIPK1_ST	Q13546	RIPK1	Q13546	RIPK1	S14	S14A	14	Missense	central	0	yes	5.452	0.000	EPSD;PhosphoSitePlus	COSMIC	2.812	Loss
TKL_RIPK_RIPK1_ST	Q13546	RIPK1	Q13546	RIPK1	S15	S14A	14	Missense	proximal	-1	no	5.478	5.416	PhosphoSitePlus;EPSD	COSMIC	2.812	Down-regulation
TKL_RIPK_RIPK1_ST	Q13546	RIPK1	Q13546	RIPK1	S20	S14A	14	Missense	distal	-6	no	5.886	5.566	EPSD;PhosphoSitePlus	COSMIC	2.812	Down-regulation
TKL_RIPK_RIPK1_ST	Q13546	RIPK1	Q13546	RIPK1	S161	D156H	156	Missense	distal	-5	no	6.228	6.262	EPSD;PhosphoSitePlus	COSMIC	2.812	Up-regulation
TKL_RIPK_RIPK1_ST	Q13546	RIPK1	Q13546	RIPK1	S333	V326L	326	Missense	distal	-7	no	2.990	2.988	EPSD	COSMIC;GDSC;CCLE	2.812	Down-regulation
TKL_RIPK_RIPK1_ST	Q5VWQ8	DAB2IP	Q13546	RIPK1	S295	L291M	291	Missense	distal	-4	no	4.371	4.322	EPSD	COSMIC	2.812	Down-regulation
TKL_RIPK_RIPK1_ST	Q5VWQ8	DAB2IP	Q13546	RIPK1	S722	R725G	725	Missense	distal	3	no	3.863	3.786	EPSD	COSMIC	2.812	Down-regulation
TKL_RIPK_RIPK1_ST	Q5VWQ8	DAB2IP	Q13546	RIPK1	S722	R725S	725	Missense	distal	3	no	3.863	3.884	EPSD	COSMIC	2.812	Up-regulation
TKL_RIPK_RIPK1_ST	Q5VWQ8	DAB2IP	Q13546	RIPK1	S722	G718W	718	Missense	distal	-4	no	3.863	3.812	EPSD	COSMIC	2.812	Down-regulation
TKL_RIPK_RIPK1_ST	Q5VWQ8	DAB2IP	Q13546	RIPK1	S722	Y729H	729	Missense	distal	7	no	3.863	3.769	EPSD	COSMIC	2.812	Down-regulation
TKL_RIPK_RIPK1_ST	Q5VWQ8	DAB2IP	Q13546	RIPK1	S722	A724V	724	Missense	proximal	2	no	3.863	3.778	EPSD	COSMIC	2.812	Down-regulation
TKL_RIPK_RIPK1_ST	Q5VWQ8	DAB2IP	Q13546	RIPK1	S722	Q720H	720	Missense	proximal	-2	no	3.863	3.675	EPSD	COSMIC	2.812	Down-regulation
TKL_RIPK_RIPK1_ST	Q5VWQ8	DAB2IP	Q13546	RIPK1	S722	S716F	716	Missense	distal	-6	no	3.863	2.832	EPSD	COSMIC	2.812	Down-regulation
TKL_RIPK_RIPK1_ST	Q5VWQ8	DAB2IP	Q13546	RIPK1	S728	R725G	725	Missense	distal	-3	no	5.915	5.950	PhosphoSitePlus	COSMIC	2.812	Up-regulation
TKL_RIPK_RIPK1_ST	Q5VWQ8	DAB2IP	Q13546	RIPK1	S728	R725S	725	Missense	distal	-3	no	5.915	5.948	PhosphoSitePlus	COSMIC	2.812	Up-regulation
TKL_RIPK_RIPK1_ST	Q5VWQ8	DAB2IP	Q13546	RIPK1	S728	Y729H	729	Missense	proximal	1	no	5.915	5.816	PhosphoSitePlus	COSMIC	2.812	Down-regulation
TKL_RIPK_RIPK1_ST	Q5VWQ8	DAB2IP	Q13546	RIPK1	S728	E734K	734	Missense	distal	6	no	5.915	5.867	PhosphoSitePlus	COSMIC	2.812	Down-regulation
TKL_RIPK_RIPK1_ST	Q5VWQ8	DAB2IP	Q13546	RIPK1	S728	A724V	724	Missense	distal	-4	no	5.915	5.894	PhosphoSitePlus	COSMIC	2.812	Down-regulation
TKL_RIPK_RIPK1_ST	Q5VWQ8	DAB2IP	Q13546	RIPK1	S728	E731K	731	Missense	distal	3	no	5.915	5.928	PhosphoSitePlus	COSMIC	2.812	Up-regulation
TKL_RIPK_RIPK1_ST	Q5VWQ8	DAB2IP	Q13546	RIPK1	S730	R725S	725	Missense	distal	-5	no	2.701	3.031	EPSD	COSMIC	2.812	Gain
TKL_RIPK_RIPK1_ST	Q5VWQ8	DAB2IP	Q13546	RIPK1	S856	H860Y	860	Missense	distal	4	no	3.263	3.376	EPSD	COSMIC	2.812	Up-regulation
TKL_RIPK_RIPK1_ST	Q5VWQ8	DAB2IP	Q13546	RIPK1	S858	E864K	864	Missense	distal	6	no	3.467	3.419	EPSD	COSMIC	2.812	Down-regulation
TKL_RIPK_RIPK1_ST	Q5VWQ8	DAB2IP	Q13546	RIPK1	S858	H860Y	860	Missense	proximal	2	no	3.467	3.547	EPSD	COSMIC	2.812	Up-regulation
TKL_RIPK_RIPK1_ST	Q5VWQ8	DAB2IP	Q13546	RIPK1	S876	A879V	879	Missense	distal	3	no	2.973	2.957	EPSD	COSMIC	2.812	Down-regulation
TKL_RIPK_RIPK1_ST	Q5VWQ8	DAB2IP	Q13546	RIPK1	S876	A879T	879	Missense	distal	3	no	2.973	3.019	EPSD	COSMIC;CCLE	2.812	Up-regulation
TKL_RIPK_RIPK1_ST	Q5VWQ8	DAB2IP	Q13546	RIPK1	S876	S876R	876	Missense	central	0	yes	2.973	0.000	EPSD	COSMIC	2.812	Loss
TKL_RIPK_RIPK1_ST	Q5VWQ8	DAB2IP	Q13546	RIPK1	S876	S874N	874	Missense	proximal	-2	no	2.973	2.924	EPSD	COSMIC	2.812	Down-regulation
TKL_RIPK_RIPK1_ST	Q5VWQ8	DAB2IP	Q13546	RIPK1	S973	R966C	966	Missense	distal	-7	no	2.778	2.835	EPSD	COSMIC	2.812	Gain
TKL_RIPK_RIPK1_ST	Q5VWQ8	DAB2IP	Q13546	RIPK1	S973	R966H	966	Missense	distal	-7	no	2.778	2.856	EPSD	COSMIC	2.812	Gain
TKL_RIPK_RIPK1_ST	Q5VWQ8	DAB2IP	Q13546	RIPK1	S973	R968S	968	Missense	distal	-5	no	2.778	3.108	EPSD	COSMIC	2.812	Gain
TKL_RIPK_RIPK1_ST	Q5VWQ8	DAB2IP	Q13546	RIPK1	S973	G976V	976	Missense	distal	3	no	2.778	2.816	EPSD	COSMIC	2.812	Gain
TKL_RIPK_RIPK1_ST	Q5VWQ8	DAB2IP	Q13546	RIPK1	S973	S974F	974	Missense	proximal	1	no	2.778	2.914	EPSD	COSMIC	2.812	Gain
TKL_RIPK_RIPK1_ST	Q5VWQ8	DAB2IP	Q13546	RIPK1	S1031	Q1037H	1037	Missense	distal	6	no	3.671	3.674	EPSD	COSMIC	2.812	Up-regulation
TKL_RIPK_RIPK1_ST	Q5VWQ8	DAB2IP	Q13546	RIPK1	S1031	E1034K	1034	Missense	distal	3	no	3.671	3.684	EPSD	COSMIC	2.812	Up-regulation
TKL_RIPK_RIPK1_ST	Q5VWQ8	DAB2IP	Q13546	RIPK1	S1031	R1028K	1028	Missense	distal	-3	no	3.671	3.681	EPSD	COSMIC	2.812	Up-regulation
TKL_RIPK_RIPK1_ST	Q5VWQ8	DAB2IP	Q13546	RIPK1	S1031	R1028M	1028	Missense	distal	-3	no	3.671	3.683	EPSD	COSMIC	2.812	Up-regulation
TKL_RIPK_RIPK1_ST	Q5VWQ8	DAB2IP	Q13546	RIPK1	S1031	P1024S	1024	Missense	distal	-7	no	3.671	3.584	EPSD	COSMIC	2.812	Down-regulation
TKL_RIPK_RIPK1_ST	Q5VWQ8	DAB2IP	Q13546	RIPK1	S1031	D1027N	1027	Missense	distal	-4	no	3.671	3.629	EPSD	COSMIC	2.812	Down-regulation
TKL_RIPK_RIPK1_ST	Q5VWQ8	DAB2IP	Q13546	RIPK1	S1031	R1026W	1026	Missense	distal	-5	no	3.671	3.730	EPSD	COSMIC	2.812	Up-regulation
TKL_RIPK_RIPK1_ST	Q5VWQ8	DAB2IP	Q13546	RIPK1	S1031	R1030M	1030	Missense	proximal	-1	no	3.671	3.654	EPSD	COSMIC	2.812	Down-regulation
TKL_RIPK_RIPK1_ST	Q5VWQ8	DAB2IP	Q13546	RIPK1	S1150	E1157D	1157	Missense	distal	7	no	3.410	3.597	EPSD	COSMIC	2.812	Up-regulation
TKL_RIPK_RIPK1_ST	Q5VWQ8	DAB2IP	Q13546	RIPK1	S1150	A1144T	1144	Missense	distal	-6	no	3.410	2.824	EPSD	COSMIC;CCLE	2.812	Down-regulation
TKL_RIPK_RIPK1_ST	Q5VWQ8	DAB2IP	Q13546	RIPK1	S1150	R1147C	1147	Missense	distal	-3	no	3.410	3.430	EPSD	COSMIC	2.812	Up-regulation
TKL_RIPK_RIPK1_ST	Q5VWQ8	DAB2IP	Q13546	RIPK1	S1150	T1153I	1153	Missense	distal	3	no	3.410	3.379	EPSD	COSMIC	2.812	Down-regulation
TKL_RIPK_RIPK1_ST	Q5VWQ8	DAB2IP	Q13546	RIPK1	S1150	R1147H	1147	Missense	distal	-3	no	3.410	3.431	EPSD	COSMIC	2.812	Up-regulation
TKL_RIPK_RIPK1_ST	Q5VWQ8	DAB2IP	Q13546	RIPK1	S1150	L1148F	1148	Missense	proximal	-2	no	3.410	3.125	EPSD	COSMIC	2.812	Down-regulation
CMGC_RCK_MAK_ICK_ST	P46379	BAG6	Q9UPZ9	ICK	T92	S96F	96	Missense	distal	4	no	2.939	2.832	EPSD	COSMIC	2.314	Down-regulation
CMGC_RCK_MAK_ICK_ST	P46379	BAG6	Q9UPZ9	ICK	S106	G103R	103	Missense	distal	-3	no	-0.883	3.193	EPSD	COSMIC	2.314	Gain
CMGC_RCK_MAK_ICK_ST	P46379	BAG6	Q9UPZ9	ICK	T185	R182Q	182	Missense	distal	-3	no	3.936	0.288	EPSD	COSMIC	2.314	Loss
CMGC_RCK_MAK_ICK_ST	P46379	BAG6	Q9UPZ9	ICK	S722	S725I	725	Missense	distal	3	no	4.079	4.076	EPSD	COSMIC	2.314	Down-regulation
CMGC_RCK_MAK_ICK_ST	P46379	BAG6	Q9UPZ9	ICK	S722	G717R	717	Missense	distal	-5	no	4.079	4.115	EPSD	COSMIC	2.314	Up-regulation
CMGC_RCK_MAK_ICK_ST	P46379	BAG6	Q9UPZ9	ICK	T978	P976H	976	Missense	proximal	-2	no	4.746	2.393	EPSD	COSMIC	2.314	Down-regulation
CMGC_RCK_MAK_ICK_ST	P46379	BAG6	Q9UPZ9	ICK	T1053	E1057K	1057	Missense	distal	4	no	4.550	4.531	EPSD	COSMIC	2.314	Down-regulation
CMGC_RCK_MAK_ICK_ST	P46379	BAG6	Q9UPZ9	ICK	T1053	A1048V	1048	Missense	distal	-5	no	4.550	4.529	EPSD	COSMIC	2.314	Down-regulation
CMGC_RCK_MAK_ICK_ST	P46379	BAG6	Q9UPZ9	ICK	T1053	R1051C	1051	Missense	proximal	-2	no	4.550	4.233	EPSD	COSMIC;GDSC;CCLE	2.314	Down-regulation
CMGC_RCK_MAK_ICK_ST	P46379	BAG6	Q9UPZ9	ICK	T1080	R1077Q	1077	Missense	distal	-3	no	11.305	7.657	PhosphoSitePlus	COSMIC	2.314	Down-regulation
CMGC_RCK_MAK_ICK_ST	P46379	BAG6	Q9UPZ9	ICK	S1084	D1088N	1088	Missense	distal	4	no	3.903	3.904	EPSD	COSMIC	2.314	Up-regulation
CMGC_RCK_MAK_ICK_ST	P46379	BAG6	Q9UPZ9	ICK	S1084	R1077Q	1077	Missense	distal	-7	no	3.903	3.956	EPSD	COSMIC	2.314	Up-regulation
CMGC_RCK_MAK_ICK_ST	Q8N122	RPTOR	Q9UPZ9	ICK	T699	S696Y	696	Missense	distal	-3	no	4.331	4.781	EPSD	COSMIC	2.314	Up-regulation
CMGC_RCK_MAK_ICK_ST	Q8N122	RPTOR	Q9UPZ9	ICK	T699	A693T	693	Missense	distal	-6	no	4.331	4.316	EPSD	COSMIC;GDSC;CCLE	2.314	Down-regulation
CMGC_RCK_MAK_ICK_ST	Q8N122	RPTOR	Q9UPZ9	ICK	T699	G702E	702	Missense	distal	3	no	4.331	4.341	EPSD	COSMIC	2.314	Up-regulation
CMGC_RCK_MAK_ICK_ST	Q8N122	RPTOR	Q9UPZ9	ICK	T699	S696A	696	Missense	distal	-3	no	4.331	4.482	EPSD	COSMIC	2.314	Up-regulation
CMGC_RCK_MAK_ICK_ST	Q8N122	RPTOR	Q9UPZ9	ICK	T714	R718C	718	Missense	distal	4	no	3.343	3.374	EPSD	COSMIC;CCLE	2.314	Up-regulation
CMGC_RCK_MAK_ICK_ST	Q8N122	RPTOR	Q9UPZ9	ICK	T714	P712L	712	Missense	proximal	-2	no	3.343	0.651	EPSD	COSMIC	2.314	Loss
CMGC_RCK_MAK_ICK_ST	Q8N122	RPTOR	Q9UPZ9	ICK	T714	P715S	715	Missense	proximal	1	no	3.343	4.122	EPSD	COSMIC	2.314	Up-regulation
CMGC_RCK_MAK_ICK_ST	Q8N122	RPTOR	Q9UPZ9	ICK	T714	D710N	710	Missense	distal	-4	no	3.343	3.339	EPSD	COSMIC	2.314	Down-regulation
CMGC_RCK_MAK_ICK_ST	Q8N122	RPTOR	Q9UPZ9	ICK	T714	S719Y	719	Missense	distal	5	no	3.343	3.293	EPSD	COSMIC	2.314	Down-regulation
CMGC_RCK_MAK_ICK_ST	Q8N122	RPTOR	Q9UPZ9	ICK	T714	S721N	721	Missense	distal	7	no	3.343	3.431	EPSD	COSMIC	2.314	Up-regulation
CMGC_RCK_MAK_ICK_ST	Q8N122	RPTOR	Q9UPZ9	ICK	T714	V720L	720	Missense	distal	6	no	3.343	3.299	EPSD	COSMIC	2.314	Down-regulation
CMGC_RCK_MAK_ICK_ST	Q8N122	RPTOR	Q9UPZ9	ICK	T714	R709G	709	Missense	distal	-5	no	3.343	3.307	EPSD	COSMIC	2.314	Down-regulation
CMGC_RCK_MAK_ICK_ST	Q8N122	RPTOR	Q9UPZ9	ICK	S719	R718C	718	Missense	proximal	-1	no	4.089	4.354	EPSD	COSMIC;CCLE	2.314	Up-regulation
CMGC_RCK_MAK_ICK_ST	Q8N122	RPTOR	Q9UPZ9	ICK	S719	P712L	712	Missense	distal	-7	no	4.089	4.164	EPSD	COSMIC	2.314	Up-regulation
CMGC_RCK_MAK_ICK_ST	Q8N122	RPTOR	Q9UPZ9	ICK	S719	P715S	715	Missense	distal	-4	no	4.089	4.117	EPSD	COSMIC	2.314	Up-regulation
CMGC_RCK_MAK_ICK_ST	Q8N122	RPTOR	Q9UPZ9	ICK	S719	S719Y	719	Missense	central	0	yes	4.089	0.000	EPSD	COSMIC	2.314	Loss
CMGC_RCK_MAK_ICK_ST	Q8N122	RPTOR	Q9UPZ9	ICK	S719	S721N	721	Missense	proximal	2	no	4.089	4.079	EPSD	COSMIC	2.314	Down-regulation
CMGC_RCK_MAK_ICK_ST	Q8N122	RPTOR	Q9UPZ9	ICK	S719	V720L	720	Missense	proximal	1	no	4.089	4.179	EPSD	COSMIC	2.314	Up-regulation
CMGC_RCK_MAK_ICK_ST	Q8N122	RPTOR	Q9UPZ9	ICK	S721	R718C	718	Missense	distal	-3	no	3.395	-0.110	EPSD	COSMIC;CCLE	2.314	Loss
CMGC_RCK_MAK_ICK_ST	Q8N122	RPTOR	Q9UPZ9	ICK	S721	P715S	715	Missense	distal	-6	no	3.395	3.516	EPSD	COSMIC	2.314	Up-regulation
CMGC_RCK_MAK_ICK_ST	Q8N122	RPTOR	Q9UPZ9	ICK	S721	S719Y	719	Missense	proximal	-2	no	3.395	3.946	EPSD	COSMIC	2.314	Up-regulation
CMGC_RCK_MAK_ICK_ST	Q8N122	RPTOR	Q9UPZ9	ICK	S721	S721N	721	Missense	central	0	yes	3.395	0.000	EPSD	COSMIC	2.314	Loss
CMGC_RCK_MAK_ICK_ST	Q8N122	RPTOR	Q9UPZ9	ICK	S721	V720L	720	Missense	proximal	-1	no	3.395	3.606	EPSD	COSMIC	2.314	Up-regulation
CMGC_RCK_MAK_ICK_ST	Q8N122	RPTOR	Q9UPZ9	ICK	S791	R789H	789	Missense	proximal	-2	no	4.211	3.849	EPSD	COSMIC;GDSC;CCLE	2.314	Down-regulation
CMGC_RCK_MAK_ICK_ST	Q8N122	RPTOR	Q9UPZ9	ICK	S791	R788C	788	Missense	distal	-3	no	4.211	0.706	EPSD	COSMIC;GDSC;CCLE	2.314	Loss
CMGC_RCK_MAK_ICK_ST	Q8N122	RPTOR	Q9UPZ9	ICK	S791	L796I	796	Missense	distal	5	no	4.211	4.019	EPSD	COSMIC	2.314	Down-regulation
CMGC_RCK_MAK_ICK_ST	Q8N122	RPTOR	Q9UPZ9	ICK	S791	R788H	788	Missense	distal	-3	no	4.211	0.549	EPSD	COSMIC	2.314	Loss
CMGC_RCK_MAK_ICK_ST	Q8N122	RPTOR	Q9UPZ9	ICK	S791	S798F	798	Missense	distal	7	no	4.211	4.287	EPSD	COSMIC	2.314	Up-regulation
CMGC_RCK_MAK_ICK_ST	Q8N122	RPTOR	Q9UPZ9	ICK	S791	I784V	784	Missense	distal	-7	no	4.211	4.212	EPSD	COSMIC	2.314	Up-regulation
CMGC_RCK_MAK_ICK_ST	Q8N122	RPTOR	Q9UPZ9	ICK	S791	S792F	792	Missense	proximal	1	no	4.211	3.690	EPSD	COSMIC	2.314	Down-regulation
CMGC_RCK_MAK_ICK_ST	Q8N122	RPTOR	Q9UPZ9	ICK	S791	A790S	790	Missense	proximal	-1	no	4.211	4.252	EPSD	COSMIC	2.314	Up-regulation
CMGC_RCK_MAK_ICK_ST	Q8N122	RPTOR	Q9UPZ9	ICK	S792	R789H	789	Missense	distal	-3	no	2.566	-1.096	EPSD	COSMIC;GDSC;CCLE	2.314	Loss
CMGC_RCK_MAK_ICK_ST	Q8N122	RPTOR	Q9UPZ9	ICK	S792	R788C	788	Missense	distal	-4	no	2.566	2.571	EPSD	COSMIC;GDSC;CCLE	2.314	Up-regulation
CMGC_RCK_MAK_ICK_ST	Q8N122	RPTOR	Q9UPZ9	ICK	S792	L796I	796	Missense	distal	4	no	2.566	2.621	EPSD	COSMIC	2.314	Up-regulation
CMGC_RCK_MAK_ICK_ST	Q8N122	RPTOR	Q9UPZ9	ICK	S792	R788H	788	Missense	distal	-4	no	2.566	2.574	EPSD	COSMIC	2.314	Up-regulation
CMGC_RCK_MAK_ICK_ST	Q8N122	RPTOR	Q9UPZ9	ICK	S792	S798F	798	Missense	distal	6	no	2.566	2.523	EPSD	COSMIC	2.314	Down-regulation
CMGC_RCK_MAK_ICK_ST	Q8N122	RPTOR	Q9UPZ9	ICK	S792	S792F	792	Missense	central	0	yes	2.566	0.000	EPSD	COSMIC	2.314	Loss
CMGC_RCK_MAK_ICK_ST	Q8N122	RPTOR	Q9UPZ9	ICK	S792	A790S	790	Missense	proximal	-2	no	2.566	2.231	EPSD	COSMIC	2.314	Loss
CMGC_RCK_MAK_ICK_ST	Q8N122	RPTOR	Q9UPZ9	ICK	S792	L799H	799	Missense	distal	7	no	2.566	2.613	EPSD	COSMIC	2.314	Up-regulation
CMGC_RCK_MAK_ICK_ST	Q8N122	RPTOR	Q9UPZ9	ICK	S863	K867R	867	Missense	distal	4	no	2.727	2.674	EPSD	COSMIC	2.314	Down-regulation
CMGC_RCK_MAK_ICK_ST	Q8N122	RPTOR	Q9UPZ9	ICK	S863	G868S	868	Missense	distal	5	no	2.727	2.670	EPSD	COSMIC	2.314	Down-regulation
CMGC_RCK_MAK_ICK_ST	Q8N122	RPTOR	Q9UPZ9	ICK	S863	P861L	861	Missense	proximal	-2	no	2.727	0.034	EPSD	COSMIC	2.314	Loss
CMGC_RCK_MAK_ICK_ST	Q8N122	RPTOR	Q9UPZ9	ICK	S863	V869M	869	Missense	distal	6	no	2.727	2.747	EPSD	COSMIC	2.314	Up-regulation
CMGC_RCK_MAK_ICK_ST	Q8N122	RPTOR	Q9UPZ9	ICK	S863	A862T	862	Missense	proximal	-1	no	2.727	2.536	EPSD	COSMIC	2.314	Down-regulation
CMGC_RCK_MAK_ICK_ST	Q8N122	RPTOR	Q9UPZ9	ICK	S881	A874V	874	Missense	distal	-7	no	3.920	3.956	EPSD	COSMIC;GDSC;CCLE	2.314	Up-regulation
CMGC_RCK_MAK_ICK_ST	Q8N122	RPTOR	Q9UPZ9	ICK	S881	P878S	878	Missense	distal	-3	no	3.920	3.024	EPSD	COSMIC	2.314	Down-regulation
CMGC_RCK_MAK_ICK_ST	Q8N122	RPTOR	Q9UPZ9	ICK	S881	P879S	879	Missense	proximal	-2	no	3.920	0.932	EPSD	COSMIC	2.314	Loss
CMGC_RCK_MAK_ICK_ST	Q8N122	RPTOR	Q9UPZ9	ICK	S881	A880S	880	Missense	proximal	-1	no	3.920	3.961	EPSD	COSMIC	2.314	Up-regulation
CMGC_RCK_MAK_ICK_ST	Q8N122	RPTOR	Q9UPZ9	ICK	S881	P878L	878	Missense	distal	-3	no	3.920	2.766	EPSD	COSMIC	2.314	Down-regulation
CMGC_RCK_MAK_ICK_ST	Q8N122	RPTOR	Q9UPZ9	ICK	T908	R905L	905	Missense	distal	-3	no	10.816	6.601	PhosphoSitePlus	COSMIC	2.314	Down-regulation
CMGC_RCK_MAK_ICK_ST	Q8N122	RPTOR	Q9UPZ9	ICK	T908	P911L	911	Missense	distal	3	no	10.816	10.948	PhosphoSitePlus	COSMIC	2.314	Up-regulation
CMGC_RCK_MAK_ICK_ST	Q8N122	RPTOR	Q9UPZ9	ICK	T908	P906Q	906	Missense	proximal	-2	no	10.816	8.467	PhosphoSitePlus	COSMIC	2.314	Down-regulation
CMGC_RCK_MAK_ICK_ST	Q8N122	RPTOR	Q9UPZ9	ICK	T908	R905W	905	Missense	distal	-3	no	10.816	7.325	PhosphoSitePlus	COSMIC	2.314	Down-regulation
CMGC_RCK_MAK_ICK_ST	Q8N122	RPTOR	Q9UPZ9	ICK	T908	G910D	910	Missense	proximal	2	no	10.816	10.840	PhosphoSitePlus	COSMIC	2.314	Up-regulation
CMGC_RCK_MAK_ICK_ST	Q8N122	RPTOR	Q9UPZ9	ICK	S920	P924T	924	Missense	distal	4	no	2.681	2.750	EPSD	COSMIC	2.314	Up-regulation
CMGC_RCK_MAK_ICK_ST	Q8N122	RPTOR	Q9UPZ9	ICK	S920	R925W	925	Missense	distal	5	no	2.681	2.498	EPSD	COSMIC	2.314	Down-regulation
CMGC_RCK_MAK_ICK_ST	Q8N122	RPTOR	Q9UPZ9	ICK	S920	Y916C	916	Missense	distal	-4	no	2.681	2.678	EPSD	COSMIC;GDSC;CCLE	2.314	Down-regulation
CMGC_RCK_MAK_ICK_ST	Q8N122	RPTOR	Q9UPZ9	ICK	S920	R925Q	925	Missense	distal	5	no	2.681	2.527	EPSD	COSMIC;CCLE	2.314	Down-regulation
CMGC_RCK_MAK_ICK_ST	Q8N122	RPTOR	Q9UPZ9	ICK	S920	R927Q	927	Missense	distal	7	no	2.681	2.530	EPSD	COSMIC	2.314	Down-regulation
CMGC_RCK_MAK_ICK_ST	Q8N122	RPTOR	Q9UPZ9	ICK	S920	R927W	927	Missense	distal	7	no	2.681	2.500	EPSD	COSMIC;CCLE	2.314	Down-regulation
CMGC_RCK_MAK_ICK_ST	Q8N122	RPTOR	Q9UPZ9	ICK	S920	Q922R	922	Missense	proximal	2	no	2.681	2.682	EPSD	COSMIC	2.314	Up-regulation
CMGC_RCK_MAK_ICK_ST	Q8N122	RPTOR	Q9UPZ9	ICK	T1122	L1119Q	1119	Missense	distal	-3	no	1.939	2.506	EPSD	COSMIC	2.314	Gain
STE_STE20_YSK_STK24_ST	Q9Y6E0	STK24	Q9Y6E0	STK24	T190	D183N	183	Missense	distal	-7	no	7.434	7.377	PhosphoSitePlus	COSMIC	2.432	Down-regulation
STE_STE20_YSK_STK24_ST	Q9Y6E0	STK24	Q9Y6E0	STK24	S373	P368L	368	Missense	distal	-5	no	3.411	3.519	EPSD	COSMIC	2.432	Up-regulation
STE_STE20_YSK_STK24_ST	Q9Y6E0	STK24	Q9Y6E0	STK24	S373	F372L	372	Missense	proximal	-1	no	3.411	3.407	EPSD	COSMIC	2.432	Down-regulation
STE_STE20_YSK_STK24_ST	Q8TAE6	PPP1R14C	Q9Y6E0	STK24	T73	R78H	78	Missense	distal	5	no	7.475	7.229	PhosphoSitePlus	COSMIC	2.432	Down-regulation
STE_STE20_YSK_STK24_ST	Q8TAE6	PPP1R14C	Q9Y6E0	STK24	T73	H67Y	67	Missense	distal	-6	no	7.475	7.463	PhosphoSitePlus	COSMIC	2.432	Down-regulation
STE_STE20_YSK_STK24_ST	Q8TAE6	PPP1R14C	Q9Y6E0	STK24	T73	Q69R	69	Missense	distal	-4	no	7.475	7.470	PhosphoSitePlus	COSMIC;GDSC;CCLE	2.432	Down-regulation
STE_STE20_YSK_STK24_ST	Q9Y2H1	STK38L	Q9Y6E0	STK24	T8	A2P	2	Missense	distal	-6	no	3.132	3.127	EPSD	COSMIC	2.432	Down-regulation
STE_STE20_YSK_STK24_ST	Q9Y2H1	STK38L	Q9Y6E0	STK24	T442	N440K	440	Missense	proximal	-2	no	8.532	8.489	PhosphoSitePlus	COSMIC	2.432	Down-regulation
STE_STE20_YSK_STK24_ST	Q9Y2H1	STK38L	Q9Y6E0	STK24	T442	F438S	438	Missense	distal	-4	no	8.532	8.503	PhosphoSitePlus	COSMIC	2.432	Down-regulation
STE_STE20_YSK_STK24_ST	Q7L7X3	TAOK1	Q9Y6E0	STK24	S60	K57N	57	Missense	distal	-3	no	3.171	3.124	EPSD	COSMIC	2.432	Down-regulation
STE_STE20_YSK_STK24_ST	Q7L7X3	TAOK1	Q9Y6E0	STK24	S60	I56M	56	Missense	distal	-4	no	3.171	3.131	EPSD	COSMIC	2.432	Down-regulation
STE_STE20_YSK_STK24_ST	Q7L7X3	TAOK1	Q9Y6E0	STK24	S575	E580K	580	Missense	distal	5	no	3.421	3.537	EPSD	COSMIC	2.432	Up-regulation
STE_STE20_YSK_STK24_ST	Q7L7X3	TAOK1	Q9Y6E0	STK24	S575	E572K	572	Missense	distal	-3	no	3.421	3.404	EPSD	COSMIC	2.432	Down-regulation
CMGC_DYRK_DYRK2_DYRK2_ST	Q13541	EIF4EBP1	Q92630	DYRK2	S65	L59Q	59	Missense	distal	-6	no	82.988	82.504	PhosphoSitePlus;EPSD	COSMIC	45.963	Down-regulation
CMGC_DYRK_DYRK2_DYRK2_ST	Q13541	EIF4EBP1	Q92630	DYRK2	S65	M60I	60	Missense	distal	-5	no	82.988	83.488	PhosphoSitePlus;EPSD	COSMIC	45.963	Up-regulation
CMGC_DYRK_DYRK2_DYRK2_ST	Q13541	EIF4EBP1	Q92630	DYRK2	S65	P72S	72	Missense	distal	7	no	82.988	79.932	PhosphoSitePlus;EPSD	COSMIC	45.963	Down-regulation
CMGC_DYRK_DYRK2_DYRK2_ST	Q13541	EIF4EBP1	Q92630	DYRK2	S65	R63W	63	Missense	proximal	-2	no	82.988	73.218	PhosphoSitePlus;EPSD	COSMIC	45.963	Down-regulation
CMGC_DYRK_DYRK2_DYRK2_ST	Q13541	EIF4EBP1	Q92630	DYRK2	T68	P72S	72	Missense	distal	4	no	47.168	47.036	EPSD	COSMIC	45.963	Down-regulation
CMGC_DYRK_DYRK2_DYRK2_ST	Q13541	EIF4EBP1	Q92630	DYRK2	T68	R63W	63	Missense	distal	-5	no	47.168	47.568	EPSD	COSMIC	45.963	Up-regulation
CMGC_DYRK_DYRK2_DYRK2_ST	Q13541	EIF4EBP1	Q92630	DYRK2	T70	P72S	72	Missense	proximal	2	no	56.720	56.206	EPSD	COSMIC	45.963	Down-regulation
CMGC_DYRK_DYRK2_DYRK2_ST	Q13541	EIF4EBP1	Q92630	DYRK2	T70	R63W	63	Missense	distal	-7	no	56.720	57.373	EPSD	COSMIC	45.963	Up-regulation
CMGC_DYRK_DYRK2_DYRK2_ST	Q13541	EIF4EBP1	Q92630	DYRK2	S83	S85F	85	Missense	proximal	2	no	57.978	57.242	EPSD	COSMIC	45.963	Down-regulation
CMGC_DYRK_DYRK2_DYRK2_ST	Q13541	EIF4EBP1	Q92630	DYRK2	S101	N100H	100	Missense	proximal	-1	no	90.431	92.398	EPSD;PhosphoSitePlus	COSMIC	45.963	Up-regulation
CMGC_DYRK_DYRK2_DYRK2_ST	Q13541	EIF4EBP1	Q92630	DYRK2	S101	R106L	106	Missense	distal	5	no	90.431	87.459	EPSD;PhosphoSitePlus	COSMIC	45.963	Down-regulation
CMGC_DYRK_DYRK2_DYRK2_ST	O43255	SIAH2	Q92630	DYRK2	S5	S2R	2	Missense	distal	-3	no	43.600	59.509	EPSD	COSMIC	45.963	Gain
CMGC_DYRK_DYRK2_DYRK2_ST	O43255	SIAH2	Q92630	DYRK2	S6	S2R	2	Missense	distal	-4	no	71.709	76.429	EPSD	COSMIC	45.963	Up-regulation
CMGC_DYRK_DYRK2_DYRK2_ST	O43255	SIAH2	Q92630	DYRK2	T7	S2R	2	Missense	distal	-5	no	63.591	62.958	EPSD	COSMIC	45.963	Down-regulation
CMGC_DYRK_DYRK2_DYRK2_ST	O43255	SIAH2	Q92630	DYRK2	T26	S28F	28	Missense	proximal	2	no	73.200	72.465	EPSD;PhosphoSitePlus	COSMIC	45.963	Down-regulation
CMGC_DYRK_DYRK2_DYRK2_ST	O43255	SIAH2	Q92630	DYRK2	T26	P27R	27	Missense	proximal	1	no	73.200	16.811	EPSD;PhosphoSitePlus	COSMIC	45.963	Loss
CMGC_DYRK_DYRK2_DYRK2_ST	O43255	SIAH2	Q92630	DYRK2	S28	S28F	28	Missense	central	0	yes	70.104	0.000	EPSD;PhosphoSitePlus	COSMIC	45.963	Loss
CMGC_DYRK_DYRK2_DYRK2_ST	O43255	SIAH2	Q92630	DYRK2	S28	P27R	27	Missense	proximal	-1	no	70.104	70.547	EPSD;PhosphoSitePlus	COSMIC	45.963	Up-regulation
CMGC_DYRK_DYRK2_DYRK2_ST	Q9Y2V2	CARHSP1	Q92630	DYRK2	S2	S3P	3	Missense	proximal	1	no	61.343	90.744	EPSD	COSMIC	45.963	Up-regulation
CMGC_DYRK_DYRK2_DYRK2_ST	Q9Y2V2	CARHSP1	Q92630	DYRK2	S17	G19R	19	Missense	proximal	2	no	47.111	47.955	EPSD	COSMIC	45.963	Up-regulation
CMGC_DYRK_DYRK2_DYRK2_ST	Q9Y2V2	CARHSP1	Q92630	DYRK2	T23	R29C	29	Missense	distal	6	no	48.159	48.534	EPSD	COSMIC	45.963	Up-regulation
CMGC_DYRK_DYRK2_DYRK2_ST	Q9Y2V2	CARHSP1	Q92630	DYRK2	T23	G19R	19	Missense	distal	-4	no	48.159	59.345	EPSD	COSMIC	45.963	Up-regulation
CMGC_DYRK_DYRK2_DYRK2_ST	Q9Y2V2	CARHSP1	Q92630	DYRK2	S30	R35W	35	Missense	distal	5	no	76.431	73.943	EPSD;PhosphoSitePlus	COSMIC	45.963	Down-regulation
CMGC_DYRK_DYRK2_DYRK2_ST	Q9Y2V2	CARHSP1	Q92630	DYRK2	S30	R29C	29	Missense	proximal	-1	no	76.431	75.438	EPSD;PhosphoSitePlus	COSMIC	45.963	Down-regulation
CMGC_DYRK_DYRK2_DYRK2_ST	Q9Y2V2	CARHSP1	Q92630	DYRK2	S30	P33S	33	Missense	distal	3	no	76.431	75.052	EPSD;PhosphoSitePlus	COSMIC	45.963	Down-regulation
CMGC_DYRK_DYRK2_DYRK2_ST	Q9Y2V2	CARHSP1	Q92630	DYRK2	S32	V39A	39	Missense	distal	7	no	78.676	75.799	EPSD;PhosphoSitePlus	COSMIC	45.963	Down-regulation
CMGC_DYRK_DYRK2_DYRK2_ST	Q9Y2V2	CARHSP1	Q92630	DYRK2	S32	R35W	35	Missense	distal	3	no	78.676	77.683	EPSD;PhosphoSitePlus	COSMIC	45.963	Down-regulation
CMGC_DYRK_DYRK2_DYRK2_ST	Q9Y2V2	CARHSP1	Q92630	DYRK2	S32	R29C	29	Missense	distal	-3	no	78.676	69.334	EPSD;PhosphoSitePlus	COSMIC	45.963	Down-regulation
CMGC_DYRK_DYRK2_DYRK2_ST	Q9Y2V2	CARHSP1	Q92630	DYRK2	S32	P33S	33	Missense	proximal	1	no	78.676	49.275	EPSD;PhosphoSitePlus	COSMIC	45.963	Down-regulation
CMGC_DYRK_DYRK2_DYRK2_ST	Q9Y2V2	CARHSP1	Q92630	DYRK2	S41	V39A	39	Missense	proximal	-2	no	79.293	75.581	PhosphoSitePlus;EPSD	COSMIC	45.963	Down-regulation
CMGC_DYRK_DYRK2_DYRK2_ST	Q9Y2V2	CARHSP1	Q92630	DYRK2	S41	R35W	35	Missense	distal	-6	no	79.293	79.386	PhosphoSitePlus;EPSD	COSMIC	45.963	Up-regulation
CMGC_DYRK_DYRK2_DYRK2_ST	Q9Y2V2	CARHSP1	Q92630	DYRK2	S41	R46H	46	Missense	distal	5	no	79.293	75.896	PhosphoSitePlus;EPSD	COSMIC	45.963	Down-regulation
CMGC_DYRK_DYRK2_DYRK2_ST	Q9Y2V2	CARHSP1	Q92630	DYRK2	T80	D87Y	87	Missense	distal	7	no	52.728	49.162	EPSD	COSMIC	45.963	Down-regulation
CMGC_DYRK_DYRK2_DYRK2_ST	Q9Y2V2	CARHSP1	Q92630	DYRK2	T80	D87N	87	Missense	distal	7	no	52.728	53.272	EPSD	COSMIC	45.963	Up-regulation
CMGC_DYRK_DYRK2_DYRK2_ST	Q9Y2V2	CARHSP1	Q92630	DYRK2	S141	I145M	145	Missense	distal	4	no	54.435	54.483	EPSD	COSMIC	45.963	Up-regulation
CMGC_DYRK_DYRK2_DYRK2_ST	O43602	DCX	Q92630	DYRK2	S147	S147F	147	Missense	central	0	yes	54.837	0.000	EPSD	COSMIC	45.963	Loss
CMGC_DYRK_DYRK2_DYRK2_ST	O43602	DCX	Q92630	DYRK2	S147	V142I	142	Missense	distal	-5	no	54.837	55.115	EPSD	COSMIC	45.963	Up-regulation
CMGC_DYRK_DYRK2_DYRK2_ST	O43602	DCX	Q92630	DYRK2	S147	S153Y	153	Missense	distal	6	no	54.837	54.676	EPSD	COSMIC	45.963	Down-regulation
CMGC_DYRK_DYRK2_DYRK2_ST	O43602	DCX	Q92630	DYRK2	S147	N145K	145	Missense	proximal	-2	no	54.837	53.905	EPSD	COSMIC	45.963	Down-regulation
CMGC_DYRK_DYRK2_DYRK2_ST	O43602	DCX	Q92630	DYRK2	S147	V142A	142	Missense	distal	-5	no	54.837	54.784	EPSD	COSMIC	45.963	Down-regulation
CMGC_DYRK_DYRK2_DYRK2_ST	O43602	DCX	Q92630	DYRK2	S287	S287F	287	Missense	central	0	yes	57.697	0.000	EPSD	COSMIC	45.963	Loss
CMGC_DYRK_DYRK2_DYRK2_ST	O43602	DCX	Q92630	DYRK2	S287	P288L	288	Missense	proximal	1	no	57.697	9.483	EPSD	COSMIC	45.963	Loss
CMGC_DYRK_DYRK2_DYRK2_ST	O43602	DCX	Q92630	DYRK2	S287	P290L	290	Missense	distal	3	no	57.697	55.925	EPSD	COSMIC	45.963	Down-regulation
CMGC_DYRK_DYRK2_DYRK2_ST	O43602	DCX	Q92630	DYRK2	S287	P288A	288	Missense	proximal	1	no	57.697	-14.796	EPSD	COSMIC	45.963	Loss
CMGC_DYRK_DYRK2_DYRK2_ST	O43602	DCX	Q92630	DYRK2	S287	P290H	290	Missense	distal	3	no	57.697	54.483	EPSD	COSMIC	45.963	Down-regulation
CMGC_DYRK_DYRK2_DYRK2_ST	O43602	DCX	Q92630	DYRK2	T289	S287F	287	Missense	proximal	-2	no	59.635	48.538	EPSD	COSMIC	45.963	Down-regulation
CMGC_DYRK_DYRK2_DYRK2_ST	O43602	DCX	Q92630	DYRK2	T289	P288L	288	Missense	proximal	-1	no	59.635	61.375	EPSD	COSMIC	45.963	Up-regulation
CMGC_DYRK_DYRK2_DYRK2_ST	O43602	DCX	Q92630	DYRK2	T289	P290L	290	Missense	proximal	1	no	59.635	11.421	EPSD	COSMIC	45.963	Loss
CMGC_DYRK_DYRK2_DYRK2_ST	O43602	DCX	Q92630	DYRK2	T289	P288A	288	Missense	proximal	-1	no	59.635	60.627	EPSD	COSMIC	45.963	Up-regulation
CMGC_DYRK_DYRK2_DYRK2_ST	O43602	DCX	Q92630	DYRK2	T289	P290H	290	Missense	proximal	1	no	59.635	-49.594	EPSD	COSMIC	45.963	Loss
CMGC_DYRK_DYRK2_DYRK2_ST	O43602	DCX	Q92630	DYRK2	S297	S297N	297	Missense	central	0	yes	58.990	0.000	EPSD	COSMIC	45.963	Loss
CMGC_DYRK_DYRK2_DYRK2_ST	O43602	DCX	Q92630	DYRK2	S297	S297I	297	Missense	central	0	yes	58.990	0.000	EPSD	COSMIC	45.963	Loss
CMGC_DYRK_DYRK2_DYRK2_ST	O43602	DCX	Q92630	DYRK2	S297	P290L	290	Missense	distal	-7	no	58.990	57.269	EPSD	COSMIC	45.963	Down-regulation
CMGC_DYRK_DYRK2_DYRK2_ST	O43602	DCX	Q92630	DYRK2	S297	P300S	300	Missense	distal	3	no	58.990	57.610	EPSD	COSMIC	45.963	Down-regulation
CMGC_DYRK_DYRK2_DYRK2_ST	O43602	DCX	Q92630	DYRK2	S297	G299V	299	Missense	proximal	2	no	58.990	59.442	EPSD	COSMIC	45.963	Up-regulation
CMGC_DYRK_DYRK2_DYRK2_ST	O43602	DCX	Q92630	DYRK2	S297	R302H	302	Missense	distal	5	no	58.990	55.593	EPSD	COSMIC	45.963	Down-regulation
CMGC_DYRK_DYRK2_DYRK2_ST	O43602	DCX	Q92630	DYRK2	S297	R303Q	303	Missense	distal	6	no	58.990	59.359	EPSD	COSMIC	45.963	Up-regulation
CMGC_DYRK_DYRK2_DYRK2_ST	O43602	DCX	Q92630	DYRK2	S297	P290H	290	Missense	distal	-7	no	58.990	55.792	EPSD	COSMIC	45.963	Down-regulation
CMGC_DYRK_DYRK2_DYRK2_ST	O43602	DCX	Q92630	DYRK2	S304	S297N	297	Missense	distal	-7	no	52.862	53.966	EPSD	COSMIC	45.963	Up-regulation
CMGC_DYRK_DYRK2_DYRK2_ST	O43602	DCX	Q92630	DYRK2	S304	S306F	306	Missense	proximal	2	no	52.862	52.127	EPSD	COSMIC	45.963	Down-regulation
CMGC_DYRK_DYRK2_DYRK2_ST	O43602	DCX	Q92630	DYRK2	S304	S297I	297	Missense	distal	-7	no	52.862	53.073	EPSD	COSMIC	45.963	Up-regulation
CMGC_DYRK_DYRK2_DYRK2_ST	O43602	DCX	Q92630	DYRK2	S304	G311D	311	Missense	distal	7	no	52.862	54.304	EPSD	COSMIC	45.963	Up-regulation
CMGC_DYRK_DYRK2_DYRK2_ST	O43602	DCX	Q92630	DYRK2	S304	P300S	300	Missense	distal	-4	no	52.862	54.130	EPSD	COSMIC	45.963	Up-regulation
CMGC_DYRK_DYRK2_DYRK2_ST	O43602	DCX	Q92630	DYRK2	S304	G299V	299	Missense	distal	-5	no	52.862	52.453	EPSD	COSMIC	45.963	Down-regulation
CMGC_DYRK_DYRK2_DYRK2_ST	O43602	DCX	Q92630	DYRK2	S304	R302H	302	Missense	proximal	-2	no	52.862	34.056	EPSD	COSMIC	45.963	Loss
CMGC_DYRK_DYRK2_DYRK2_ST	O43602	DCX	Q92630	DYRK2	S304	G311S	311	Missense	distal	7	no	52.862	52.670	EPSD	COSMIC	45.963	Down-regulation
CMGC_DYRK_DYRK2_DYRK2_ST	O43602	DCX	Q92630	DYRK2	S304	G311V	311	Missense	distal	7	no	52.862	54.878	EPSD	COSMIC	45.963	Up-regulation
CMGC_DYRK_DYRK2_DYRK2_ST	O43602	DCX	Q92630	DYRK2	S304	G311C	311	Missense	distal	7	no	52.862	54.306	EPSD	COSMIC	45.963	Up-regulation
CMGC_DYRK_DYRK2_DYRK2_ST	O43602	DCX	Q92630	DYRK2	S304	R303Q	303	Missense	proximal	-1	no	52.862	52.423	EPSD	COSMIC	45.963	Down-regulation
CMGC_DYRK_DYRK2_DYRK2_ST	O43602	DCX	Q92630	DYRK2	S306	S306F	306	Missense	central	0	yes	91.991	0.000	PhosphoSitePlus	COSMIC	45.963	Loss
CMGC_DYRK_DYRK2_DYRK2_ST	O43602	DCX	Q92630	DYRK2	S306	G311D	311	Missense	distal	5	no	91.991	94.410	PhosphoSitePlus	COSMIC	45.963	Up-regulation
CMGC_DYRK_DYRK2_DYRK2_ST	O43602	DCX	Q92630	DYRK2	S306	D313N	313	Missense	distal	7	no	91.991	92.535	PhosphoSitePlus	COSMIC	45.963	Up-regulation
CMGC_DYRK_DYRK2_DYRK2_ST	O43602	DCX	Q92630	DYRK2	S306	P300S	300	Missense	distal	-6	no	91.991	92.143	PhosphoSitePlus	COSMIC	45.963	Up-regulation
CMGC_DYRK_DYRK2_DYRK2_ST	O43602	DCX	Q92630	DYRK2	S306	G299V	299	Missense	distal	-7	no	91.991	92.923	PhosphoSitePlus	COSMIC	45.963	Up-regulation
CMGC_DYRK_DYRK2_DYRK2_ST	O43602	DCX	Q92630	DYRK2	S306	N312D	312	Missense	distal	6	no	91.991	91.695	PhosphoSitePlus	COSMIC	45.963	Down-regulation
CMGC_DYRK_DYRK2_DYRK2_ST	O43602	DCX	Q92630	DYRK2	S306	R302H	302	Missense	distal	-4	no	91.991	84.557	PhosphoSitePlus	COSMIC	45.963	Down-regulation
CMGC_DYRK_DYRK2_DYRK2_ST	O43602	DCX	Q92630	DYRK2	S306	G311S	311	Missense	distal	5	no	91.991	92.798	PhosphoSitePlus	COSMIC	45.963	Up-regulation
CMGC_DYRK_DYRK2_DYRK2_ST	O43602	DCX	Q92630	DYRK2	S306	N312K	312	Missense	distal	6	no	91.991	91.976	PhosphoSitePlus	COSMIC	45.963	Down-regulation
CMGC_DYRK_DYRK2_DYRK2_ST	O43602	DCX	Q92630	DYRK2	S306	G311V	311	Missense	distal	5	no	91.991	92.573	PhosphoSitePlus	COSMIC	45.963	Up-regulation
CMGC_DYRK_DYRK2_DYRK2_ST	O43602	DCX	Q92630	DYRK2	S306	G311C	311	Missense	distal	5	no	91.991	94.574	PhosphoSitePlus	COSMIC	45.963	Up-regulation
CMGC_DYRK_DYRK2_DYRK2_ST	O43602	DCX	Q92630	DYRK2	S306	D313G	313	Missense	distal	7	no	91.991	90.549	PhosphoSitePlus	COSMIC;CCLE	45.963	Down-regulation
CMGC_DYRK_DYRK2_DYRK2_ST	O43602	DCX	Q92630	DYRK2	S306	R303Q	303	Missense	distal	-3	no	91.991	76.574	PhosphoSitePlus	COSMIC	45.963	Down-regulation
CMGC_DYRK_DYRK2_DYRK2_ST	O43602	DCX	Q92630	DYRK2	S310	S306F	306	Missense	distal	-4	no	47.527	40.258	EPSD	COSMIC	45.963	Loss
CMGC_DYRK_DYRK2_DYRK2_ST	O43602	DCX	Q92630	DYRK2	S310	N317D	317	Missense	distal	7	no	47.527	46.983	EPSD	COSMIC	45.963	Down-regulation
CMGC_DYRK_DYRK2_DYRK2_ST	O43602	DCX	Q92630	DYRK2	S310	G311D	311	Missense	proximal	1	no	47.527	36.041	EPSD	COSMIC	45.963	Loss
CMGC_DYRK_DYRK2_DYRK2_ST	O43602	DCX	Q92630	DYRK2	S310	D313N	313	Missense	distal	3	no	47.527	47.245	EPSD	COSMIC	45.963	Down-regulation
CMGC_DYRK_DYRK2_DYRK2_ST	O43602	DCX	Q92630	DYRK2	S310	N312D	312	Missense	proximal	2	no	47.527	47.061	EPSD	COSMIC	45.963	Down-regulation
CMGC_DYRK_DYRK2_DYRK2_ST	O43602	DCX	Q92630	DYRK2	S310	G311S	311	Missense	proximal	1	no	47.527	39.311	EPSD	COSMIC	45.963	Loss
CMGC_DYRK_DYRK2_DYRK2_ST	O43602	DCX	Q92630	DYRK2	S310	N312K	312	Missense	proximal	2	no	47.527	47.297	EPSD	COSMIC	45.963	Down-regulation
CMGC_DYRK_DYRK2_DYRK2_ST	O43602	DCX	Q92630	DYRK2	S310	G311V	311	Missense	proximal	1	no	47.527	60.680	EPSD	COSMIC	45.963	Up-regulation
CMGC_DYRK_DYRK2_DYRK2_ST	O43602	DCX	Q92630	DYRK2	S310	G311C	311	Missense	proximal	1	no	47.527	5.594	EPSD	COSMIC	45.963	Loss
CMGC_DYRK_DYRK2_DYRK2_ST	O43602	DCX	Q92630	DYRK2	S310	D313G	313	Missense	distal	3	no	47.527	46.868	EPSD	COSMIC;CCLE	45.963	Down-regulation
CMGC_DYRK_DYRK2_DYRK2_ST	O43602	DCX	Q92630	DYRK2	S310	R303Q	303	Missense	distal	-7	no	47.527	49.046	EPSD	COSMIC	45.963	Up-regulation
CMGC_DYRK_DYRK2_DYRK2_ST	O43602	DCX	Q92630	DYRK2	T326	P327S	327	Missense	proximal	1	no	56.324	26.924	EPSD	COSMIC	45.963	Loss
CMGC_DYRK_DYRK2_DYRK2_ST	O43602	DCX	Q92630	DYRK2	T326	S320Y	320	Missense	distal	-6	no	56.324	56.333	EPSD	COSMIC	45.963	Up-regulation
CMGC_DYRK_DYRK2_DYRK2_ST	O43602	DCX	Q92630	DYRK2	T326	S329F	329	Missense	distal	3	no	56.324	54.907	EPSD	COSMIC	45.963	Down-regulation
CMGC_DYRK_DYRK2_DYRK2_ST	O43602	DCX	Q92630	DYRK2	T326	S320A	320	Missense	distal	-6	no	56.324	56.338	EPSD	COSMIC	45.963	Up-regulation
CMGC_DYRK_DYRK2_DYRK2_ST	O43602	DCX	Q92630	DYRK2	T326	Q331H	331	Missense	distal	5	no	56.324	53.713	EPSD	COSMIC	45.963	Down-regulation
CMGC_DYRK_DYRK2_DYRK2_ST	O43602	DCX	Q92630	DYRK2	T326	S320F	320	Missense	distal	-6	no	56.324	56.542	EPSD	COSMIC	45.963	Up-regulation
CMGC_DYRK_DYRK2_DYRK2_ST	O43602	DCX	Q92630	DYRK2	T326	P327R	327	Missense	proximal	1	no	56.324	-0.065	EPSD	COSMIC	45.963	Loss
CMGC_DYRK_DYRK2_DYRK2_ST	O43602	DCX	Q92630	DYRK2	S329	P327S	327	Missense	proximal	-2	no	48.207	45.519	EPSD	COSMIC	45.963	Loss
CMGC_DYRK_DYRK2_DYRK2_ST	O43602	DCX	Q92630	DYRK2	S329	S329F	329	Missense	central	0	yes	48.207	0.000	EPSD	COSMIC	45.963	Loss
CMGC_DYRK_DYRK2_DYRK2_ST	O43602	DCX	Q92630	DYRK2	S329	T336M	336	Missense	distal	7	no	48.207	47.094	EPSD	COSMIC	45.963	Down-regulation
CMGC_DYRK_DYRK2_DYRK2_ST	O43602	DCX	Q92630	DYRK2	S329	Q331H	331	Missense	proximal	2	no	48.207	46.840	EPSD	COSMIC	45.963	Down-regulation
CMGC_DYRK_DYRK2_DYRK2_ST	O43602	DCX	Q92630	DYRK2	S329	P327R	327	Missense	proximal	-2	no	48.207	53.660	EPSD	COSMIC	45.963	Up-regulation
CMGC_DYRK_DYRK2_DYRK2_ST	O43602	DCX	Q92630	DYRK2	S332	P327S	327	Missense	distal	-5	no	52.727	53.871	EPSD	COSMIC	45.963	Up-regulation
CMGC_DYRK_DYRK2_DYRK2_ST	O43602	DCX	Q92630	DYRK2	S332	S329F	329	Missense	distal	-3	no	52.727	44.971	EPSD	COSMIC	45.963	Loss
CMGC_DYRK_DYRK2_DYRK2_ST	O43602	DCX	Q92630	DYRK2	S332	T336M	336	Missense	distal	4	no	52.727	52.706	EPSD	COSMIC	45.963	Down-regulation
CMGC_DYRK_DYRK2_DYRK2_ST	O43602	DCX	Q92630	DYRK2	S332	T338N	338	Missense	distal	6	no	52.727	52.772	EPSD	COSMIC	45.963	Up-regulation
CMGC_DYRK_DYRK2_DYRK2_ST	O43602	DCX	Q92630	DYRK2	S332	Q331H	331	Missense	proximal	-1	no	52.727	55.690	EPSD	COSMIC	45.963	Up-regulation
CMGC_DYRK_DYRK2_DYRK2_ST	O43602	DCX	Q92630	DYRK2	S332	P327R	327	Missense	distal	-5	no	52.727	53.238	EPSD	COSMIC	45.963	Up-regulation
CMGC_DYRK_DYRK2_DYRK2_ST	O43602	DCX	Q92630	DYRK2	T336	P340S	340	Missense	distal	4	no	56.708	56.576	EPSD	COSMIC	45.963	Down-regulation
CMGC_DYRK_DYRK2_DYRK2_ST	O43602	DCX	Q92630	DYRK2	T336	G341D	341	Missense	distal	5	no	56.708	59.126	EPSD	COSMIC	45.963	Up-regulation
CMGC_DYRK_DYRK2_DYRK2_ST	O43602	DCX	Q92630	DYRK2	T336	S329F	329	Missense	distal	-7	no	56.708	55.705	EPSD	COSMIC	45.963	Down-regulation
CMGC_DYRK_DYRK2_DYRK2_ST	O43602	DCX	Q92630	DYRK2	T336	P340T	340	Missense	distal	4	no	56.708	56.642	EPSD	COSMIC	45.963	Down-regulation
CMGC_DYRK_DYRK2_DYRK2_ST	O43602	DCX	Q92630	DYRK2	T336	T336M	336	Missense	central	0	yes	56.708	0.000	EPSD	COSMIC	45.963	Loss
CMGC_DYRK_DYRK2_DYRK2_ST	O43602	DCX	Q92630	DYRK2	T336	T338N	338	Missense	proximal	2	no	56.708	57.339	EPSD	COSMIC	45.963	Up-regulation
CMGC_DYRK_DYRK2_DYRK2_ST	O43602	DCX	Q92630	DYRK2	T336	Q331H	331	Missense	distal	-5	no	56.708	58.268	EPSD	COSMIC	45.963	Up-regulation
CMGC_DYRK_DYRK2_DYRK2_ST	O43602	DCX	Q92630	DYRK2	S339	P340S	340	Missense	proximal	1	no	59.208	29.808	EPSD	COSMIC	45.963	Loss
CMGC_DYRK_DYRK2_DYRK2_ST	O43602	DCX	Q92630	DYRK2	S339	G341D	341	Missense	proximal	2	no	59.208	59.674	EPSD	COSMIC	45.963	Up-regulation
CMGC_DYRK_DYRK2_DYRK2_ST	O43602	DCX	Q92630	DYRK2	S339	P340T	340	Missense	proximal	1	no	59.208	37.133	EPSD	COSMIC	45.963	Loss
CMGC_DYRK_DYRK2_DYRK2_ST	O43602	DCX	Q92630	DYRK2	S339	T336M	336	Missense	distal	-3	no	59.208	61.915	EPSD	COSMIC	45.963	Up-regulation
CMGC_DYRK_DYRK2_DYRK2_ST	O43602	DCX	Q92630	DYRK2	S339	T338N	338	Missense	proximal	-1	no	59.208	60.065	EPSD	COSMIC	45.963	Up-regulation
CMGC_DYRK_DYRK2_DYRK2_ST	O43602	DCX	Q92630	DYRK2	S339	R344W	344	Missense	distal	5	no	59.208	56.721	EPSD	COSMIC	45.963	Down-regulation
CMGC_DYRK_DYRK2_DYRK2_ST	O43602	DCX	Q92630	DYRK2	S339	H346N	346	Missense	distal	7	no	59.208	65.725	EPSD	COSMIC	45.963	Up-regulation
CMGC_DYRK_DYRK2_DYRK2_ST	O75449	KATNA1	Q92630	DYRK2	S109	R115H	115	Missense	distal	6	no	90.013	89.588	EPSD;PhosphoSitePlus	COSMIC;CCLE	45.963	Down-regulation
CMGC_DYRK_DYRK2_DYRK2_ST	O75449	KATNA1	Q92630	DYRK2	T441	N447Y	447	Missense	distal	6	no	47.492	47.049	EPSD	COSMIC;GDSC;CCLE	45.963	Down-regulation
CMGC_DYRK_DYRK2_DYRK2_ST	P04637	TP53	Q92630	DYRK2	S9	E11Q	11	Missense	proximal	2	no	56.920	57.776	EPSD	COSMIC;GDSC;CCLE	45.963	Up-regulation
CMGC_DYRK_DYRK2_DYRK2_ST	P04637	TP53	Q92630	DYRK2	S9	Q16L	16	Missense	distal	7	no	56.920	54.428	EPSD	COSMIC;GDSC;CCLE	45.963	Down-regulation
CMGC_DYRK_DYRK2_DYRK2_ST	P04637	TP53	Q92630	DYRK2	S9	P13S	13	Missense	distal	4	no	56.920	56.789	EPSD	COSMIC	45.963	Down-regulation
CMGC_DYRK_DYRK2_DYRK2_ST	P04637	TP53	Q92630	DYRK2	S9	V10I	10	Missense	proximal	1	no	56.920	20.637	EPSD	COSMIC	45.963	Loss
CMGC_DYRK_DYRK2_DYRK2_ST	P04637	TP53	Q92630	DYRK2	S9	P8L	8	Missense	proximal	-1	no	56.920	58.660	EPSD	COSMIC	45.963	Up-regulation
CMGC_DYRK_DYRK2_DYRK2_ST	P04637	TP53	Q92630	DYRK2	S9	P8S	8	Missense	proximal	-1	no	56.920	58.404	EPSD	COSMIC	45.963	Up-regulation
CMGC_DYRK_DYRK2_DYRK2_ST	P04637	TP53	Q92630	DYRK2	S9	P13L	13	Missense	distal	4	no	56.920	56.706	EPSD	COSMIC	45.963	Down-regulation
CMGC_DYRK_DYRK2_DYRK2_ST	P04637	TP53	Q92630	DYRK2	S9	Q5H	5	Missense	distal	-4	no	56.920	50.233	EPSD	COSMIC	45.963	Down-regulation
CMGC_DYRK_DYRK2_DYRK2_ST	P04637	TP53	Q92630	DYRK2	S9	V10G	10	Missense	proximal	1	no	56.920	43.768	EPSD	COSMIC	45.963	Loss
CMGC_DYRK_DYRK2_DYRK2_ST	P04637	TP53	Q92630	DYRK2	S9	E3G	3	Missense	distal	-6	no	56.920	56.853	EPSD	COSMIC	45.963	Down-regulation
CMGC_DYRK_DYRK2_DYRK2_ST	P04637	TP53	Q92630	DYRK2	S9	D7H	7	Missense	proximal	-2	no	56.920	45.333	EPSD	COSMIC	45.963	Loss
CMGC_DYRK_DYRK2_DYRK2_ST	P04637	TP53	Q92630	DYRK2	S9	S9G	9	Missense	central	0	yes	56.920	0.000	EPSD	COSMIC	45.963	Loss
CMGC_DYRK_DYRK2_DYRK2_ST	P04637	TP53	Q92630	DYRK2	S9	S15I	15	Missense	distal	6	no	56.920	56.806	EPSD	COSMIC	45.963	Down-regulation
CMGC_DYRK_DYRK2_DYRK2_ST	P04637	TP53	Q92630	DYRK2	S9	D7Y	7	Missense	proximal	-2	no	56.920	52.078	EPSD	COSMIC	45.963	Down-regulation
CMGC_DYRK_DYRK2_DYRK2_ST	P04637	TP53	Q92630	DYRK2	S33	M40I	40	Missense	distal	7	no	50.772	49.826	EPSD	COSMIC	45.963	Down-regulation
CMGC_DYRK_DYRK2_DYRK2_ST	P04637	TP53	Q92630	DYRK2	S33	V31I	31	Missense	proximal	-2	no	50.772	44.767	EPSD	COSMIC;GDSC;CCLE	45.963	Loss
CMGC_DYRK_DYRK2_DYRK2_ST	P04637	TP53	Q92630	DYRK2	S33	P36L	36	Missense	distal	3	no	50.772	48.999	EPSD	COSMIC;GDSC;CCLE	45.963	Down-regulation
CMGC_DYRK_DYRK2_DYRK2_ST	P04637	TP53	Q92630	DYRK2	S33	L35F	35	Missense	proximal	2	no	50.772	50.485	EPSD	COSMIC	45.963	Down-regulation
CMGC_DYRK_DYRK2_DYRK2_ST	P04637	TP53	Q92630	DYRK2	S33	Q38L	38	Missense	distal	5	no	50.772	48.586	EPSD	COSMIC	45.963	Down-regulation
CMGC_DYRK_DYRK2_DYRK2_ST	P04637	TP53	Q92630	DYRK2	S33	S37T	37	Missense	distal	4	no	50.772	50.838	EPSD	COSMIC	45.963	Up-regulation
CMGC_DYRK_DYRK2_DYRK2_ST	P04637	TP53	Q92630	DYRK2	S33	L26P	26	Missense	distal	-7	no	50.772	52.492	EPSD	COSMIC	45.963	Up-regulation
CMGC_DYRK_DYRK2_DYRK2_ST	P04637	TP53	Q92630	DYRK2	S33	P36S	36	Missense	distal	3	no	50.772	49.392	EPSD	COSMIC;GDSC;CCLE	45.963	Down-regulation
CMGC_DYRK_DYRK2_DYRK2_ST	P04637	TP53	Q92630	DYRK2	S33	A39V	39	Missense	distal	6	no	50.772	51.166	EPSD	COSMIC	45.963	Up-regulation
CMGC_DYRK_DYRK2_DYRK2_ST	P04637	TP53	Q92630	DYRK2	S33	A39S	39	Missense	distal	6	no	50.772	50.741	EPSD	COSMIC	45.963	Down-regulation
CMGC_DYRK_DYRK2_DYRK2_ST	P04637	TP53	Q92630	DYRK2	S33	N30K	30	Missense	distal	-3	no	50.772	49.313	EPSD	COSMIC	45.963	Down-regulation
CMGC_DYRK_DYRK2_DYRK2_ST	P04637	TP53	Q92630	DYRK2	S33	A39T	39	Missense	distal	6	no	50.772	50.978	EPSD	COSMIC	45.963	Up-regulation
CMGC_DYRK_DYRK2_DYRK2_ST	P04637	TP53	Q92630	DYRK2	S33	P27T	27	Missense	distal	-6	no	50.772	50.753	EPSD	COSMIC	45.963	Down-regulation
CMGC_DYRK_DYRK2_DYRK2_ST	P04637	TP53	Q92630	DYRK2	S33	P36R	36	Missense	distal	3	no	50.772	50.564	EPSD	COSMIC	45.963	Down-regulation
CMGC_DYRK_DYRK2_DYRK2_ST	P04637	TP53	Q92630	DYRK2	S33	L35R	35	Missense	proximal	2	no	50.772	51.859	EPSD	COSMIC	45.963	Up-regulation
CMGC_DYRK_DYRK2_DYRK2_ST	P04637	TP53	Q92630	DYRK2	S33	L35H	35	Missense	proximal	2	no	50.772	50.946	EPSD	COSMIC	45.963	Up-regulation
CMGC_DYRK_DYRK2_DYRK2_ST	P04637	TP53	Q92630	DYRK2	S33	L35P	35	Missense	proximal	2	no	50.772	51.734	EPSD	COSMIC	45.963	Up-regulation
CMGC_DYRK_DYRK2_DYRK2_ST	P04637	TP53	Q92630	DYRK2	S33	L35I	35	Missense	proximal	2	no	50.772	51.274	EPSD	COSMIC	45.963	Up-regulation
CMGC_DYRK_DYRK2_DYRK2_ST	P04637	TP53	Q92630	DYRK2	S33	L35V	35	Missense	proximal	2	no	50.772	51.467	EPSD	COSMIC	45.963	Up-regulation
CMGC_DYRK_DYRK2_DYRK2_ST	P04637	TP53	Q92630	DYRK2	S46	M40I	40	Missense	distal	-6	no	78.736	78.885	PhosphoSitePlus	COSMIC	45.963	Up-regulation
CMGC_DYRK_DYRK2_DYRK2_ST	P04637	TP53	Q92630	DYRK2	S46	W53C	53	Missense	distal	7	no	78.736	79.735	PhosphoSitePlus	COSMIC	45.963	Up-regulation
CMGC_DYRK_DYRK2_DYRK2_ST	P04637	TP53	Q92630	DYRK2	S46	W53G	53	Missense	distal	7	no	78.736	78.291	PhosphoSitePlus	COSMIC	45.963	Down-regulation
CMGC_DYRK_DYRK2_DYRK2_ST	P04637	TP53	Q92630	DYRK2	S46	S46F	46	Missense	central	0	yes	78.736	0.000	PhosphoSitePlus	COSMIC	45.963	Loss
CMGC_DYRK_DYRK2_DYRK2_ST	P04637	TP53	Q92630	DYRK2	S46	D49Y	49	Missense	distal	3	no	78.736	77.446	PhosphoSitePlus	COSMIC	45.963	Down-regulation
CMGC_DYRK_DYRK2_DYRK2_ST	P04637	TP53	Q92630	DYRK2	S46	P47L	47	Missense	proximal	1	no	78.736	30.522	PhosphoSitePlus	COSMIC	45.963	Loss
CMGC_DYRK_DYRK2_DYRK2_ST	P04637	TP53	Q92630	DYRK2	S46	D49H	49	Missense	distal	3	no	78.736	76.028	PhosphoSitePlus	COSMIC;GDSC;CCLE	45.963	Down-regulation
CMGC_DYRK_DYRK2_DYRK2_ST	P04637	TP53	Q92630	DYRK2	S46	P47S	47	Missense	proximal	1	no	78.736	49.336	PhosphoSitePlus	COSMIC	45.963	Down-regulation
CMGC_DYRK_DYRK2_DYRK2_ST	P04637	TP53	Q92630	DYRK2	S46	D41N	41	Missense	distal	-5	no	78.736	79.533	PhosphoSitePlus	COSMIC	45.963	Up-regulation
CMGC_DYRK_DYRK2_DYRK2_ST	P04637	TP53	Q92630	DYRK2	S46	D48H	48	Missense	proximal	2	no	78.736	78.201	PhosphoSitePlus	COSMIC	45.963	Down-regulation
CMGC_DYRK_DYRK2_DYRK2_ST	P04637	TP53	Q92630	DYRK2	S46	D49N	49	Missense	distal	3	no	78.736	78.454	PhosphoSitePlus	COSMIC	45.963	Down-regulation
CMGC_DYRK_DYRK2_DYRK2_ST	P04637	TP53	Q92630	DYRK2	S46	M44I	44	Missense	proximal	-2	no	78.736	71.663	PhosphoSitePlus	COSMIC	45.963	Down-regulation
CMGC_DYRK_DYRK2_DYRK2_ST	P04637	TP53	Q92630	DYRK2	S46	Q52H	52	Missense	distal	6	no	78.736	77.941	PhosphoSitePlus	COSMIC	45.963	Down-regulation
CMGC_DYRK_DYRK2_DYRK2_ST	P04637	TP53	Q92630	DYRK2	S46	D49V	49	Missense	distal	3	no	78.736	78.090	PhosphoSitePlus	COSMIC	45.963	Down-regulation
CMGC_DYRK_DYRK2_DYRK2_ST	P04637	TP53	Q92630	DYRK2	S46	A39V	39	Missense	distal	-7	no	78.736	80.000	PhosphoSitePlus	COSMIC	45.963	Up-regulation
CMGC_DYRK_DYRK2_DYRK2_ST	P04637	TP53	Q92630	DYRK2	S46	A39S	39	Missense	distal	-7	no	78.736	78.852	PhosphoSitePlus	COSMIC	45.963	Up-regulation
CMGC_DYRK_DYRK2_DYRK2_ST	P04637	TP53	Q92630	DYRK2	S46	D42Y	42	Missense	distal	-4	no	78.736	75.588	PhosphoSitePlus	COSMIC	45.963	Down-regulation
CMGC_DYRK_DYRK2_DYRK2_ST	P04637	TP53	Q92630	DYRK2	S46	M44R	44	Missense	proximal	-2	no	78.736	84.254	PhosphoSitePlus	COSMIC	45.963	Up-regulation
CMGC_DYRK_DYRK2_DYRK2_ST	P04637	TP53	Q92630	DYRK2	S46	S46P	46	Missense	central	0	yes	78.736	0.000	PhosphoSitePlus	COSMIC	45.963	Loss
CMGC_DYRK_DYRK2_DYRK2_ST	P04637	TP53	Q92630	DYRK2	S46	M44V	44	Missense	proximal	-2	no	78.736	77.668	PhosphoSitePlus	COSMIC	45.963	Down-regulation
CMGC_DYRK_DYRK2_DYRK2_ST	P04637	TP53	Q92630	DYRK2	S46	L45P	45	Missense	proximal	-1	no	78.736	76.996	PhosphoSitePlus	COSMIC	45.963	Down-regulation
CMGC_DYRK_DYRK2_DYRK2_ST	P04637	TP53	Q92630	DYRK2	S46	M44T	44	Missense	proximal	-2	no	78.736	73.647	PhosphoSitePlus	COSMIC	45.963	Down-regulation
CMGC_DYRK_DYRK2_DYRK2_ST	P04637	TP53	Q92630	DYRK2	S46	A39T	39	Missense	distal	-7	no	78.736	79.952	PhosphoSitePlus	COSMIC	45.963	Up-regulation
CMGC_DYRK_DYRK2_DYRK2_ST	P04637	TP53	Q92630	DYRK2	S46	L43F	43	Missense	distal	-3	no	78.736	69.558	PhosphoSitePlus	COSMIC	45.963	Down-regulation
CMGC_DYRK_DYRK2_DYRK2_ST	P04637	TP53	Q92630	DYRK2	S46	D41H	41	Missense	distal	-5	no	78.736	80.133	PhosphoSitePlus	COSMIC	45.963	Up-regulation
CMGC_DYRK_DYRK2_DYRK2_ST	P04637	TP53	Q92630	DYRK2	S46	D49E	49	Missense	distal	3	no	78.736	76.690	PhosphoSitePlus	COSMIC	45.963	Down-regulation
CMGC_DYRK_DYRK2_DYRK2_ST	P04637	TP53	Q92630	DYRK2	S46	D49G	49	Missense	distal	3	no	78.736	78.076	PhosphoSitePlus	COSMIC	45.963	Down-regulation
CMGC_DYRK_DYRK2_DYRK2_ST	P04637	TP53	Q92630	DYRK2	S46	D48A	48	Missense	proximal	2	no	78.736	78.840	PhosphoSitePlus	COSMIC	45.963	Up-regulation
CMGC_DYRK_DYRK2_DYRK2_ST	P04637	TP53	Q92630	DYRK2	S46	D48Y	48	Missense	proximal	2	no	78.736	78.817	PhosphoSitePlus	COSMIC	45.963	Up-regulation
CMGC_DYRK_DYRK2_DYRK2_ST	P04637	TP53	Q92630	DYRK2	S46	D48E	48	Missense	proximal	2	no	78.736	78.713	PhosphoSitePlus	COSMIC	45.963	Down-regulation
CMGC_DYRK_DYRK2_DYRK2_ST	P04637	TP53	Q92630	DYRK2	S46	D49I	49	Missense	distal	3	no	78.736	77.710	PhosphoSitePlus	COSMIC	45.963	Down-regulation
CMGC_DYRK_DYRK2_DYRK2_ST	P04637	TP53	Q92630	DYRK2	S46	D41E	41	Missense	distal	-5	no	78.736	79.340	PhosphoSitePlus	COSMIC	45.963	Up-regulation
CMGC_DYRK_DYRK2_DYRK2_ST	P04637	TP53	Q92630	DYRK2	T55	E56K	56	Missense	proximal	1	no	-42.794	52.987	EPSD	COSMIC	45.963	Gain
CMGC_DYRK_DYRK2_DYRK2_ST	P04637	TP53	Q92630	DYRK2	T55	E56V	56	Missense	proximal	1	no	-42.794	61.152	EPSD	COSMIC	45.963	Gain
CMGC_DYRK_DYRK2_DYRK2_ST	P04637	TP53	Q92630	DYRK2	T81	P77A	77	Missense	distal	-4	no	57.238	56.678	EPSD	COSMIC	45.963	Down-regulation
CMGC_DYRK_DYRK2_DYRK2_ST	P04637	TP53	Q92630	DYRK2	T81	A76T	76	Missense	distal	-5	no	57.238	56.525	EPSD	COSMIC	45.963	Down-regulation
CMGC_DYRK_DYRK2_DYRK2_ST	P04637	TP53	Q92630	DYRK2	T81	A83T	83	Missense	proximal	2	no	57.238	56.968	EPSD	COSMIC	45.963	Down-regulation
CMGC_DYRK_DYRK2_DYRK2_ST	P04637	TP53	Q92630	DYRK2	T81	T81I	81	Missense	central	0	yes	57.238	0.000	EPSD	COSMIC	45.963	Loss
CMGC_DYRK_DYRK2_DYRK2_ST	P04637	TP53	Q92630	DYRK2	T81	A84V	84	Missense	distal	3	no	57.238	58.968	EPSD	COSMIC	45.963	Up-regulation
CMGC_DYRK_DYRK2_DYRK2_ST	P04637	TP53	Q92630	DYRK2	T81	P80L	80	Missense	proximal	-1	no	57.238	58.977	EPSD	COSMIC	45.963	Up-regulation
CMGC_DYRK_DYRK2_DYRK2_ST	P04637	TP53	Q92630	DYRK2	T81	A86V	86	Missense	distal	5	no	57.238	56.624	EPSD	COSMIC	45.963	Down-regulation
CMGC_DYRK_DYRK2_DYRK2_ST	P04637	TP53	Q92630	DYRK2	T81	P85S	85	Missense	distal	4	no	57.238	57.106	EPSD	COSMIC	45.963	Down-regulation
CMGC_DYRK_DYRK2_DYRK2_ST	P04637	TP53	Q92630	DYRK2	T81	A79T	79	Missense	proximal	-2	no	57.238	56.928	EPSD	COSMIC	45.963	Down-regulation
CMGC_DYRK_DYRK2_DYRK2_ST	P04637	TP53	Q92630	DYRK2	T81	A84G	84	Missense	distal	3	no	57.238	58.955	EPSD	COSMIC	45.963	Up-regulation
CMGC_DYRK_DYRK2_DYRK2_ST	P04637	TP53	Q92630	DYRK2	T81	A78V	78	Missense	distal	-3	no	57.238	52.028	EPSD	COSMIC	45.963	Down-regulation
CMGC_DYRK_DYRK2_DYRK2_ST	P04637	TP53	Q92630	DYRK2	T81	A78S	78	Missense	distal	-3	no	57.238	54.435	EPSD	COSMIC	45.963	Down-regulation
CMGC_DYRK_DYRK2_DYRK2_ST	P04637	TP53	Q92630	DYRK2	T81	P87L	87	Missense	distal	6	no	57.238	56.753	EPSD	COSMIC	45.963	Down-regulation
CMGC_DYRK_DYRK2_DYRK2_ST	P04637	TP53	Q92630	DYRK2	T81	P85L	85	Missense	distal	4	no	57.238	57.023	EPSD	COSMIC	45.963	Down-regulation
CMGC_DYRK_DYRK2_DYRK2_ST	P04637	TP53	Q92630	DYRK2	T81	P82S	82	Missense	proximal	1	no	57.238	27.837	EPSD	COSMIC	45.963	Loss
CMGC_DYRK_DYRK2_DYRK2_ST	P04637	TP53	Q92630	DYRK2	T81	P77S	77	Missense	distal	-4	no	57.238	58.506	EPSD	COSMIC	45.963	Up-regulation
CMGC_DYRK_DYRK2_DYRK2_ST	P04637	TP53	Q92630	DYRK2	T81	P80S	80	Missense	proximal	-1	no	57.238	58.721	EPSD	COSMIC	45.963	Up-regulation
CMGC_DYRK_DYRK2_DYRK2_ST	P04637	TP53	Q92630	DYRK2	T81	A84T	84	Missense	distal	3	no	57.238	59.547	EPSD	COSMIC	45.963	Up-regulation
CMGC_DYRK_DYRK2_DYRK2_ST	P04637	TP53	Q92630	DYRK2	T81	A83E	83	Missense	proximal	2	no	57.238	57.110	EPSD	COSMIC	45.963	Down-regulation
CMGC_DYRK_DYRK2_DYRK2_ST	P04637	TP53	Q92630	DYRK2	T81	P85T	85	Missense	distal	4	no	57.238	57.172	EPSD	COSMIC	45.963	Down-regulation
CMGC_DYRK_DYRK2_DYRK2_ST	P04637	TP53	Q92630	DYRK2	T81	A74V	74	Missense	distal	-7	no	57.238	58.501	EPSD	COSMIC	45.963	Up-regulation
CMGC_DYRK_DYRK2_DYRK2_ST	P04637	TP53	Q92630	DYRK2	T81	P75S	75	Missense	distal	-6	no	57.238	57.390	EPSD	COSMIC	45.963	Up-regulation
CMGC_DYRK_DYRK2_DYRK2_ST	P04637	TP53	Q92630	DYRK2	T81	A76V	76	Missense	distal	-5	no	57.238	57.290	EPSD	COSMIC	45.963	Up-regulation
CMGC_DYRK_DYRK2_DYRK2_ST	P04637	TP53	Q92630	DYRK2	T81	P75R	75	Missense	distal	-6	no	57.238	57.235	EPSD	COSMIC	45.963	Down-regulation
CMGC_DYRK_DYRK2_DYRK2_ST	P04637	TP53	Q92630	DYRK2	T81	P87H	87	Missense	distal	6	no	57.238	56.592	EPSD	COSMIC	45.963	Down-regulation
CMGC_DYRK_DYRK2_DYRK2_ST	P04637	TP53	Q92630	DYRK2	T81	P87T	87	Missense	distal	6	no	57.238	57.204	EPSD	COSMIC	45.963	Down-regulation
CMGC_DYRK_DYRK2_DYRK2_ST	P04637	TP53	Q92630	DYRK2	T81	P87S	87	Missense	distal	6	no	57.238	56.966	EPSD	COSMIC	45.963	Down-regulation
CMGC_DYRK_DYRK2_DYRK2_ST	P04637	TP53	Q92630	DYRK2	T81	P87R	87	Missense	distal	6	no	57.238	57.017	EPSD	COSMIC	45.963	Down-regulation
CMGC_DYRK_DYRK2_DYRK2_ST	P04637	TP53	Q92630	DYRK2	T81	P87C	87	Missense	distal	6	no	57.238	57.393	EPSD	COSMIC	45.963	Up-regulation
CMGC_DYRK_DYRK2_DYRK2_ST	P04637	TP53	Q92630	DYRK2	T81	A86E	86	Missense	distal	5	no	57.238	57.450	EPSD	COSMIC	45.963	Up-regulation
CMGC_DYRK_DYRK2_DYRK2_ST	P04637	TP53	Q92630	DYRK2	T81	A86S	86	Missense	distal	5	no	57.238	56.850	EPSD	COSMIC	45.963	Down-regulation
CMGC_DYRK_DYRK2_DYRK2_ST	P04637	TP53	Q92630	DYRK2	T81	A83V	83	Missense	proximal	2	no	57.238	57.120	EPSD	COSMIC	45.963	Down-regulation
CMGC_DYRK_DYRK2_DYRK2_ST	P04637	TP53	Q92630	DYRK2	S149	W146R	146	Missense	distal	-3	no	41.068	55.614	EPSD	COSMIC	45.963	Gain
CMGC_DYRK_DYRK2_DYRK2_ST	P04637	TP53	Q92630	DYRK2	S149	T150K	150	Missense	proximal	1	no	41.068	46.947	EPSD	COSMIC	45.963	Gain
CMGC_DYRK_DYRK2_DYRK2_ST	P04637	TP53	Q92630	DYRK2	S149	W146C	146	Missense	distal	-3	no	41.068	46.272	EPSD	COSMIC	45.963	Gain
CMGC_DYRK_DYRK2_DYRK2_ST	P04637	TP53	Q92630	DYRK2	T150	P151N	151	Missense	proximal	1	no	53.573	23.990	EPSD	COSMIC	45.963	Loss
CMGC_DYRK_DYRK2_DYRK2_ST	P04637	TP53	Q92630	DYRK2	T150	P152A	152	Missense	proximal	2	no	53.573	53.424	EPSD	COSMIC	45.963	Down-regulation
CMGC_DYRK_DYRK2_DYRK2_ST	P04637	TP53	Q92630	DYRK2	T150	P152T	152	Missense	proximal	2	no	53.573	53.155	EPSD	COSMIC	45.963	Down-regulation
CMGC_DYRK_DYRK2_DYRK2_ST	P04637	TP53	Q92630	DYRK2	T150	P152H	152	Missense	proximal	2	no	53.573	52.785	EPSD	COSMIC	45.963	Down-regulation
CMGC_DYRK_DYRK2_DYRK2_ST	P04637	TP53	Q92630	DYRK2	T150	P153T	153	Missense	distal	3	no	53.573	53.001	EPSD	COSMIC	45.963	Down-regulation
CMGC_DYRK_DYRK2_DYRK2_ST	P04637	TP53	Q92630	DYRK2	T150	V147I	147	Missense	distal	-3	no	53.573	53.718	EPSD	COSMIC	45.963	Up-regulation
CMGC_DYRK_DYRK2_DYRK2_ST	P04637	TP53	Q92630	DYRK2	T150	P153L	153	Missense	distal	3	no	53.573	51.801	EPSD	COSMIC	45.963	Down-regulation
CMGC_DYRK_DYRK2_DYRK2_ST	P04637	TP53	Q92630	DYRK2	T150	V147D	147	Missense	distal	-3	no	53.573	60.412	EPSD	COSMIC;GDSC;CCLE	45.963	Up-regulation
CMGC_DYRK_DYRK2_DYRK2_ST	P04637	TP53	Q92630	DYRK2	T150	S149P	149	Missense	proximal	-1	no	53.573	52.090	EPSD	COSMIC	45.963	Down-regulation
CMGC_DYRK_DYRK2_DYRK2_ST	P04637	TP53	Q92630	DYRK2	T150	P152K	152	Missense	proximal	2	no	53.573	53.556	EPSD	COSMIC	45.963	Down-regulation
CMGC_DYRK_DYRK2_DYRK2_ST	P04637	TP53	Q92630	DYRK2	T150	P153S	153	Missense	distal	3	no	53.573	52.194	EPSD	COSMIC	45.963	Down-regulation
CMGC_DYRK_DYRK2_DYRK2_ST	P04637	TP53	Q92630	DYRK2	T150	G154C	154	Missense	distal	4	no	53.573	53.847	EPSD	COSMIC	45.963	Up-regulation
CMGC_DYRK_DYRK2_DYRK2_ST	P04637	TP53	Q92630	DYRK2	T150	S149F	149	Missense	proximal	-1	no	53.573	54.782	EPSD	COSMIC	45.963	Up-regulation
CMGC_DYRK_DYRK2_DYRK2_ST	P04637	TP53	Q92630	DYRK2	T150	G154D	154	Missense	distal	4	no	53.573	53.739	EPSD	COSMIC	45.963	Up-regulation
CMGC_DYRK_DYRK2_DYRK2_ST	P04637	TP53	Q92630	DYRK2	T150	V157I	157	Missense	distal	7	no	53.573	51.111	EPSD	COSMIC	45.963	Down-regulation
CMGC_DYRK_DYRK2_DYRK2_ST	P04637	TP53	Q92630	DYRK2	T150	W146R	146	Missense	distal	-4	no	53.573	60.448	EPSD	COSMIC	45.963	Up-regulation
CMGC_DYRK_DYRK2_DYRK2_ST	P04637	TP53	Q92630	DYRK2	T150	Q144R	144	Missense	distal	-6	no	53.573	53.734	EPSD	COSMIC	45.963	Up-regulation
CMGC_DYRK_DYRK2_DYRK2_ST	P04637	TP53	Q92630	DYRK2	T150	D148V	148	Missense	proximal	-2	no	53.573	54.208	EPSD	COSMIC	45.963	Up-regulation
CMGC_DYRK_DYRK2_DYRK2_ST	P04637	TP53	Q92630	DYRK2	T150	S149Y	149	Missense	proximal	-1	no	53.573	53.710	EPSD	COSMIC	45.963	Up-regulation
CMGC_DYRK_DYRK2_DYRK2_ST	P04637	TP53	Q92630	DYRK2	T150	T150I	150	Missense	central	0	yes	53.573	0.000	EPSD	COSMIC	45.963	Loss
CMGC_DYRK_DYRK2_DYRK2_ST	P04637	TP53	Q92630	DYRK2	T150	S149T	149	Missense	proximal	-1	no	53.573	52.233	EPSD	COSMIC	45.963	Down-regulation
CMGC_DYRK_DYRK2_DYRK2_ST	P04637	TP53	Q92630	DYRK2	T150	W146G	146	Missense	distal	-4	no	53.573	49.263	EPSD	COSMIC	45.963	Down-regulation
CMGC_DYRK_DYRK2_DYRK2_ST	P04637	TP53	Q92630	DYRK2	T150	L145M	145	Missense	distal	-5	no	53.573	53.245	EPSD	COSMIC	45.963	Down-regulation
CMGC_DYRK_DYRK2_DYRK2_ST	P04637	TP53	Q92630	DYRK2	T150	V143L	143	Missense	distal	-7	no	53.573	51.929	EPSD	COSMIC	45.963	Down-regulation
CMGC_DYRK_DYRK2_DYRK2_ST	P04637	TP53	Q92630	DYRK2	T150	R156S	156	Missense	distal	6	no	53.573	53.522	EPSD	COSMIC	45.963	Down-regulation
CMGC_DYRK_DYRK2_DYRK2_ST	P04637	TP53	Q92630	DYRK2	T150	D148E	148	Missense	proximal	-2	no	53.573	46.068	EPSD	COSMIC	45.963	Down-regulation
CMGC_DYRK_DYRK2_DYRK2_ST	P04637	TP53	Q92630	DYRK2	T150	V147F	147	Missense	distal	-3	no	53.573	48.223	EPSD	COSMIC	45.963	Down-regulation
CMGC_DYRK_DYRK2_DYRK2_ST	P04637	TP53	Q92630	DYRK2	T150	T155A	155	Missense	distal	5	no	53.573	53.487	EPSD	COSMIC	45.963	Down-regulation
CMGC_DYRK_DYRK2_DYRK2_ST	P04637	TP53	Q92630	DYRK2	T150	V147E	147	Missense	distal	-3	no	53.573	56.334	EPSD	COSMIC	45.963	Up-regulation
CMGC_DYRK_DYRK2_DYRK2_ST	P04637	TP53	Q92630	DYRK2	T150	G154I	154	Missense	distal	4	no	53.573	53.600	EPSD	COSMIC	45.963	Up-regulation
CMGC_DYRK_DYRK2_DYRK2_ST	P04637	TP53	Q92630	DYRK2	T150	D148G	148	Missense	proximal	-2	no	53.573	49.276	EPSD	COSMIC	45.963	Down-regulation
CMGC_DYRK_DYRK2_DYRK2_ST	P04637	TP53	Q92630	DYRK2	T150	Q144K	144	Missense	distal	-6	no	53.573	53.690	EPSD	COSMIC	45.963	Up-regulation
CMGC_DYRK_DYRK2_DYRK2_ST	P04637	TP53	Q92630	DYRK2	T150	V147A	147	Missense	distal	-3	no	53.573	58.783	EPSD	COSMIC	45.963	Up-regulation
CMGC_DYRK_DYRK2_DYRK2_ST	P04637	TP53	Q92630	DYRK2	T150	L145V	145	Missense	distal	-5	no	53.573	53.466	EPSD	COSMIC	45.963	Down-regulation
CMGC_DYRK_DYRK2_DYRK2_ST	P04637	TP53	Q92630	DYRK2	T150	T150K	150	Missense	central	0	yes	53.573	0.000	EPSD	COSMIC	45.963	Loss
CMGC_DYRK_DYRK2_DYRK2_ST	P04637	TP53	Q92630	DYRK2	T150	P153H	153	Missense	distal	3	no	53.573	50.360	EPSD	COSMIC	45.963	Down-regulation
CMGC_DYRK_DYRK2_DYRK2_ST	P04637	TP53	Q92630	DYRK2	T150	V157E	157	Missense	distal	7	no	53.573	48.746	EPSD	COSMIC	45.963	Down-regulation
CMGC_DYRK_DYRK2_DYRK2_ST	P04637	TP53	Q92630	DYRK2	T150	T155S	155	Missense	distal	5	no	53.573	53.099	EPSD	COSMIC;CCLE	45.963	Down-regulation
CMGC_DYRK_DYRK2_DYRK2_ST	P04637	TP53	Q92630	DYRK2	T150	D148H	148	Missense	proximal	-2	no	53.573	41.987	EPSD	COSMIC	45.963	Loss
CMGC_DYRK_DYRK2_DYRK2_ST	P04637	TP53	Q92630	DYRK2	T150	P153A	153	Missense	distal	3	no	53.573	50.691	EPSD	COSMIC	45.963	Down-regulation
CMGC_DYRK_DYRK2_DYRK2_ST	P04637	TP53	Q92630	DYRK2	T150	T150R	150	Missense	central	0	yes	53.573	0.000	EPSD	COSMIC	45.963	Loss
CMGC_DYRK_DYRK2_DYRK2_ST	P04637	TP53	Q92630	DYRK2	T150	T155L	155	Missense	distal	5	no	53.573	52.611	EPSD	COSMIC	45.963	Down-regulation
CMGC_DYRK_DYRK2_DYRK2_ST	P04637	TP53	Q92630	DYRK2	T150	G154A	154	Missense	distal	4	no	53.573	53.495	EPSD	COSMIC	45.963	Down-regulation
CMGC_DYRK_DYRK2_DYRK2_ST	P04637	TP53	Q92630	DYRK2	T150	T150A	150	Missense	central	0	yes	53.573	0.000	EPSD	COSMIC	45.963	Loss
CMGC_DYRK_DYRK2_DYRK2_ST	P04637	TP53	Q92630	DYRK2	T150	W146C	146	Missense	distal	-4	no	53.573	60.425	EPSD	COSMIC	45.963	Up-regulation
CMGC_DYRK_DYRK2_DYRK2_ST	P04637	TP53	Q92630	DYRK2	T150	P153F	153	Missense	distal	3	no	53.573	50.777	EPSD	COSMIC	45.963	Down-regulation
CMGC_DYRK_DYRK2_DYRK2_ST	P04637	TP53	Q92630	DYRK2	T150	D148Y	148	Missense	proximal	-2	no	53.573	48.731	EPSD	COSMIC	45.963	Down-regulation
CMGC_DYRK_DYRK2_DYRK2_ST	P04637	TP53	Q92630	DYRK2	T150	G154R	154	Missense	distal	4	no	53.573	53.709	EPSD	COSMIC	45.963	Up-regulation
CMGC_DYRK_DYRK2_DYRK2_ST	P04637	TP53	Q92630	DYRK2	S215	R209Q	209	Missense	distal	-6	no	56.176	56.015	EPSD	COSMIC	45.963	Down-regulation
CMGC_DYRK_DYRK2_DYRK2_ST	P04637	TP53	Q92630	DYRK2	S215	R209W	209	Missense	distal	-6	no	56.176	56.269	EPSD	COSMIC	45.963	Up-regulation
CMGC_DYRK_DYRK2_DYRK2_ST	P04637	TP53	Q92630	DYRK2	S215	R209P	209	Missense	distal	-6	no	56.176	56.178	EPSD	COSMIC	45.963	Up-regulation
CMGC_DYRK_DYRK2_DYRK2_ST	P04637	TP53	Q92630	DYRK2	S215	R209L	209	Missense	distal	-6	no	56.176	56.499	EPSD	COSMIC	45.963	Up-regulation
CMGC_DYRK_DYRK2_DYRK2_ST	P04637	TP53	Q92630	DYRK2	S215	R209G	209	Missense	distal	-6	no	56.176	56.338	EPSD	COSMIC	45.963	Up-regulation
CMGC_DYRK_DYRK2_DYRK2_ST	P04637	TP53	Q92630	DYRK2	S215	R209C	209	Missense	distal	-6	no	56.176	55.942	EPSD	COSMIC	45.963	Down-regulation
CMGC_DYRK_DYRK2_DYRK2_ST	P04637	TP53	Q92630	DYRK2	S215	V216A	216	Missense	proximal	1	no	56.176	-8.286	EPSD	COSMIC	45.963	Loss
CMGC_DYRK_DYRK2_DYRK2_ST	P04637	TP53	Q92630	DYRK2	S215	V217A	217	Missense	proximal	2	no	56.176	56.294	EPSD	COSMIC	45.963	Up-regulation
CMGC_DYRK_DYRK2_DYRK2_ST	P04637	TP53	Q92630	DYRK2	S215	P222S	222	Missense	distal	7	no	56.176	53.120	EPSD	COSMIC	45.963	Down-regulation
CMGC_DYRK_DYRK2_DYRK2_ST	P04637	TP53	Q92630	DYRK2	S215	P219L	219	Missense	distal	4	no	56.176	55.962	EPSD	COSMIC	45.963	Down-regulation
CMGC_DYRK_DYRK2_DYRK2_ST	P04637	TP53	Q92630	DYRK2	S215	V218M	218	Missense	distal	3	no	56.176	55.821	EPSD	COSMIC	45.963	Down-regulation
CMGC_DYRK_DYRK2_DYRK2_ST	P04637	TP53	Q92630	DYRK2	S215	D208E	208	Missense	distal	-7	no	56.176	54.283	EPSD	COSMIC	45.963	Down-regulation
CMGC_DYRK_DYRK2_DYRK2_ST	P04637	TP53	Q92630	DYRK2	S215	F212L	212	Missense	distal	-3	no	56.176	65.354	EPSD	COSMIC	45.963	Up-regulation
CMGC_DYRK_DYRK2_DYRK2_ST	P04637	TP53	Q92630	DYRK2	S215	H214Q	214	Missense	proximal	-1	no	56.176	53.213	EPSD	COSMIC	45.963	Down-regulation
CMGC_DYRK_DYRK2_DYRK2_ST	P04637	TP53	Q92630	DYRK2	S215	P219H	219	Missense	distal	4	no	56.176	55.812	EPSD	COSMIC	45.963	Down-regulation
CMGC_DYRK_DYRK2_DYRK2_ST	P04637	TP53	Q92630	DYRK2	S215	R213W	213	Missense	proximal	-2	no	56.176	46.406	EPSD	COSMIC	45.963	Down-regulation
CMGC_DYRK_DYRK2_DYRK2_ST	P04637	TP53	Q92630	DYRK2	S215	N210D	210	Missense	distal	-5	no	56.176	55.378	EPSD	COSMIC	45.963	Down-regulation
CMGC_DYRK_DYRK2_DYRK2_ST	P04637	TP53	Q92630	DYRK2	S215	V218A	218	Missense	distal	3	no	56.176	54.445	EPSD	COSMIC	45.963	Down-regulation
CMGC_DYRK_DYRK2_DYRK2_ST	P04637	TP53	Q92630	DYRK2	S215	S215C	215	Missense	central	0	yes	56.176	0.000	EPSD	COSMIC;GDSC;CCLE	45.963	Loss
CMGC_DYRK_DYRK2_DYRK2_ST	P04637	TP53	Q92630	DYRK2	S215	V218L	218	Missense	distal	3	no	56.176	55.555	EPSD	COSMIC;GDSC;CCLE	45.963	Down-regulation
CMGC_DYRK_DYRK2_DYRK2_ST	P04637	TP53	Q92630	DYRK2	S215	T211N	211	Missense	distal	-4	no	56.176	64.238	EPSD	COSMIC	45.963	Up-regulation
CMGC_DYRK_DYRK2_DYRK2_ST	P04637	TP53	Q92630	DYRK2	S215	N210S	210	Missense	distal	-5	no	56.176	55.988	EPSD	COSMIC	45.963	Down-regulation
CMGC_DYRK_DYRK2_DYRK2_ST	P04637	TP53	Q92630	DYRK2	S215	P222T	222	Missense	distal	7	no	56.176	54.924	EPSD	COSMIC	45.963	Down-regulation
CMGC_DYRK_DYRK2_DYRK2_ST	P04637	TP53	Q92630	DYRK2	S215	F212I	212	Missense	distal	-3	no	56.176	61.671	EPSD	COSMIC	45.963	Up-regulation
CMGC_DYRK_DYRK2_DYRK2_ST	P04637	TP53	Q92630	DYRK2	S215	N210H	210	Missense	distal	-5	no	56.176	56.776	EPSD	COSMIC	45.963	Up-regulation
CMGC_DYRK_DYRK2_DYRK2_ST	P04637	TP53	Q92630	DYRK2	S215	E221G	221	Missense	distal	6	no	56.176	56.147	EPSD	COSMIC	45.963	Down-regulation
CMGC_DYRK_DYRK2_DYRK2_ST	P04637	TP53	Q92630	DYRK2	S215	E221D	221	Missense	distal	6	no	56.176	56.265	EPSD	COSMIC	45.963	Up-regulation
CMGC_DYRK_DYRK2_DYRK2_ST	P04637	TP53	Q92630	DYRK2	S215	V217E	217	Missense	proximal	2	no	56.176	56.166	EPSD	COSMIC	45.963	Down-regulation
CMGC_DYRK_DYRK2_DYRK2_ST	P04637	TP53	Q92630	DYRK2	S215	R209T	209	Missense	distal	-6	no	56.176	56.160	EPSD	COSMIC	45.963	Down-regulation
CMGC_DYRK_DYRK2_DYRK2_ST	P04637	TP53	Q92630	DYRK2	S215	P222L	222	Missense	distal	7	no	56.176	52.353	EPSD	COSMIC	45.963	Down-regulation
CMGC_DYRK_DYRK2_DYRK2_ST	P04637	TP53	Q92630	DYRK2	S215	P219R	219	Missense	distal	4	no	56.176	56.151	EPSD	COSMIC	45.963	Down-regulation
CMGC_DYRK_DYRK2_DYRK2_ST	P04637	TP53	Q92630	DYRK2	S215	P219S	219	Missense	distal	4	no	56.176	56.044	EPSD	COSMIC	45.963	Down-regulation
CMGC_DYRK_DYRK2_DYRK2_ST	P04637	TP53	Q92630	DYRK2	S215	D208Y	208	Missense	distal	-7	no	56.176	54.419	EPSD	COSMIC	45.963	Down-regulation
CMGC_DYRK_DYRK2_DYRK2_ST	P04637	TP53	Q92630	DYRK2	S215	P222Q	222	Missense	distal	7	no	56.176	54.845	EPSD	COSMIC	45.963	Down-regulation
CMGC_DYRK_DYRK2_DYRK2_ST	P04637	TP53	Q92630	DYRK2	S215	P222A	222	Missense	distal	7	no	56.176	52.451	EPSD	COSMIC	45.963	Down-regulation
CMGC_DYRK_DYRK2_DYRK2_ST	P04637	TP53	Q92630	DYRK2	S215	V217L	217	Missense	proximal	2	no	56.176	55.480	EPSD	COSMIC	45.963	Down-regulation
CMGC_DYRK_DYRK2_DYRK2_ST	P04637	TP53	Q92630	DYRK2	S215	T211S	211	Missense	distal	-4	no	56.176	60.714	EPSD	COSMIC	45.963	Up-regulation
CMGC_DYRK_DYRK2_DYRK2_ST	P04637	TP53	Q92630	DYRK2	S215	D208H	208	Missense	distal	-7	no	56.176	53.475	EPSD	COSMIC	45.963	Down-regulation
CMGC_DYRK_DYRK2_DYRK2_ST	P04637	TP53	Q92630	DYRK2	S215	V217M	217	Missense	proximal	2	no	56.176	56.415	EPSD	COSMIC	45.963	Up-regulation
CMGC_DYRK_DYRK2_DYRK2_ST	P04637	TP53	Q92630	DYRK2	S215	N210T	210	Missense	distal	-5	no	56.176	55.211	EPSD	COSMIC	45.963	Down-regulation
CMGC_DYRK_DYRK2_DYRK2_ST	P04637	TP53	Q92630	DYRK2	S215	N210K	210	Missense	distal	-5	no	56.176	55.161	EPSD	COSMIC	45.963	Down-regulation
CMGC_DYRK_DYRK2_DYRK2_ST	P04637	TP53	Q92630	DYRK2	S215	F212S	212	Missense	distal	-3	no	56.176	63.933	EPSD	COSMIC	45.963	Up-regulation
CMGC_DYRK_DYRK2_DYRK2_ST	P04637	TP53	Q92630	DYRK2	S215	H214P	214	Missense	proximal	-1	no	56.176	53.209	EPSD	COSMIC	45.963	Down-regulation
CMGC_DYRK_DYRK2_DYRK2_ST	P04637	TP53	Q92630	DYRK2	S215	D208I	208	Missense	distal	-7	no	56.176	55.659	EPSD	COSMIC	45.963	Down-regulation
CMGC_DYRK_DYRK2_DYRK2_ST	P04637	TP53	Q92630	DYRK2	S215	P219C	219	Missense	distal	4	no	56.176	56.289	EPSD	COSMIC	45.963	Up-regulation
CMGC_DYRK_DYRK2_DYRK2_ST	P04637	TP53	Q92630	DYRK2	S215	F212Y	212	Missense	distal	-3	no	56.176	67.551	EPSD	COSMIC	45.963	Up-regulation
CMGC_DYRK_DYRK2_DYRK2_ST	P04637	TP53	Q92630	DYRK2	S215	Y220L	220	Missense	distal	5	no	56.176	55.066	EPSD	COSMIC	45.963	Down-regulation
CMGC_DYRK_DYRK2_DYRK2_ST	P04637	TP53	Q92630	DYRK2	S215	Y220X	220	Missense	distal	5	no	56.176	55.632	EPSD	COSMIC	45.963	Down-regulation
CMGC_DYRK_DYRK2_DYRK2_ST	P04637	TP53	Q92630	DYRK2	S215	H214A	214	Missense	proximal	-1	no	56.176	54.201	EPSD	COSMIC	45.963	Down-regulation
CMGC_DYRK_DYRK2_DYRK2_ST	P04637	TP53	Q92630	DYRK2	T284	E285G	285	Missense	proximal	1	no	-29.043	61.751	EPSD	COSMIC	45.963	Gain
CMGC_DYRK_DYRK2_DYRK2_ST	P04637	TP53	Q92630	DYRK2	S313	N310T	310	Missense	distal	-3	no	47.453	43.344	EPSD	COSMIC	45.963	Loss
CMGC_DYRK_DYRK2_DYRK2_ST	P04637	TP53	Q92630	DYRK2	S313	Q317R	317	Missense	distal	4	no	47.453	47.485	EPSD	COSMIC	45.963	Up-regulation
CMGC_DYRK_DYRK2_DYRK2_ST	P04637	TP53	Q92630	DYRK2	S313	P309S	309	Missense	distal	-4	no	47.453	48.721	EPSD	COSMIC;GDSC;CCLE	45.963	Up-regulation
CMGC_DYRK_DYRK2_DYRK2_ST	P04637	TP53	Q92630	DYRK2	S313	K319E	319	Missense	distal	6	no	47.453	47.083	EPSD	COSMIC	45.963	Down-regulation
CMGC_DYRK_DYRK2_DYRK2_ST	P04637	TP53	Q92630	DYRK2	S313	K320N	320	Missense	distal	7	no	47.453	47.953	EPSD	COSMIC;GDSC;CCLE	45.963	Up-regulation
CMGC_DYRK_DYRK2_DYRK2_ST	P04637	TP53	Q92630	DYRK2	S313	N310L	310	Missense	distal	-3	no	47.453	44.711	EPSD	COSMIC	45.963	Loss
CMGC_DYRK_DYRK2_DYRK2_ST	P04637	TP53	Q92630	DYRK2	S313	T312S	312	Missense	proximal	-1	no	47.453	48.793	EPSD	COSMIC	45.963	Up-regulation
CMGC_DYRK_DYRK2_DYRK2_ST	P04637	TP53	Q92630	DYRK2	S313	N311Y	311	Missense	proximal	-2	no	47.453	40.494	EPSD	COSMIC	45.963	Loss
CMGC_DYRK_DYRK2_DYRK2_ST	P04637	TP53	Q92630	DYRK2	S313	R306P	306	Missense	distal	-7	no	47.453	48.887	EPSD	COSMIC	45.963	Up-regulation
CMGC_DYRK_DYRK2_DYRK2_ST	P04637	TP53	Q92630	DYRK2	S313	A307T	307	Missense	distal	-6	no	47.453	47.269	EPSD	COSMIC	45.963	Down-regulation
CMGC_DYRK_DYRK2_DYRK2_ST	P04637	TP53	Q92630	DYRK2	S313	N311K	311	Missense	proximal	-2	no	47.453	46.521	EPSD	COSMIC	45.963	Down-regulation
CMGC_DYRK_DYRK2_DYRK2_ST	P04637	TP53	Q92630	DYRK2	S313	S315P	315	Missense	proximal	2	no	47.453	47.967	EPSD	COSMIC	45.963	Up-regulation
CMGC_DYRK_DYRK2_DYRK2_ST	P04637	TP53	Q92630	DYRK2	S313	N310H	310	Missense	distal	-3	no	47.453	39.422	EPSD	COSMIC	45.963	Loss
CMGC_DYRK_DYRK2_DYRK2_ST	P04637	TP53	Q92630	DYRK2	S313	R306Q	306	Missense	distal	-7	no	47.453	48.972	EPSD	COSMIC	45.963	Up-regulation
CMGC_DYRK_DYRK2_DYRK2_ST	P04637	TP53	Q92630	DYRK2	S313	S314C	314	Missense	proximal	1	no	47.453	13.736	EPSD	COSMIC	45.963	Loss
CMGC_DYRK_DYRK2_DYRK2_ST	P04637	TP53	Q92630	DYRK2	S313	P318A	318	Missense	distal	5	no	47.453	47.387	EPSD	COSMIC	45.963	Down-regulation
CMGC_DYRK_DYRK2_DYRK2_ST	P04637	TP53	Q92630	DYRK2	S313	P316L	316	Missense	distal	3	no	47.453	45.681	EPSD	COSMIC	45.963	Loss
CMGC_DYRK_DYRK2_DYRK2_ST	P04637	TP53	Q92630	DYRK2	S313	L308M	308	Missense	distal	-5	no	47.453	47.124	EPSD	COSMIC	45.963	Down-regulation
CMGC_DYRK_DYRK2_DYRK2_ST	P04637	TP53	Q92630	DYRK2	S313	S313C	313	Missense	central	0	yes	47.453	0.000	EPSD	COSMIC	45.963	Loss
CMGC_DYRK_DYRK2_DYRK2_ST	P04637	TP53	Q92630	DYRK2	S313	N311H	311	Missense	proximal	-2	no	47.453	33.749	EPSD	COSMIC	45.963	Loss
CMGC_DYRK_DYRK2_DYRK2_ST	P04637	TP53	Q92630	DYRK2	S313	L308V	308	Missense	distal	-5	no	47.453	47.346	EPSD	COSMIC	45.963	Down-regulation
CMGC_DYRK_DYRK2_DYRK2_ST	P04637	TP53	Q92630	DYRK2	S313	S314F	314	Missense	proximal	1	no	47.453	15.156	EPSD	COSMIC	45.963	Loss
CMGC_DYRK_DYRK2_DYRK2_ST	P04637	TP53	Q92630	DYRK2	S313	K319R	319	Missense	distal	6	no	47.453	47.237	EPSD	COSMIC	45.963	Down-regulation
CMGC_DYRK_DYRK2_DYRK2_ST	P04637	TP53	Q92630	DYRK2	S313	T312A	312	Missense	proximal	-1	no	47.453	48.302	EPSD	COSMIC	45.963	Up-regulation
CMGC_DYRK_DYRK2_DYRK2_ST	P04637	TP53	Q92630	DYRK2	S313	N310D	310	Missense	distal	-3	no	47.453	47.721	EPSD	COSMIC	45.963	Up-regulation
CMGC_DYRK_DYRK2_DYRK2_ST	P04637	TP53	Q92630	DYRK2	S313	N311D	311	Missense	proximal	-2	no	47.453	45.336	EPSD	COSMIC	45.963	Loss
CMGC_DYRK_DYRK2_DYRK2_ST	P04637	TP53	Q92630	DYRK2	S313	P309R	309	Missense	distal	-4	no	47.453	53.441	EPSD	COSMIC	45.963	Up-regulation
CMGC_DYRK_DYRK2_DYRK2_ST	P04637	TP53	Q92630	DYRK2	S313	S313N	313	Missense	central	0	yes	47.453	0.000	EPSD	COSMIC	45.963	Loss
CMGC_DYRK_DYRK2_DYRK2_ST	P04637	TP53	Q92630	DYRK2	S313	Q317P	317	Missense	distal	4	no	47.453	47.510	EPSD	COSMIC	45.963	Up-regulation
CMGC_DYRK_DYRK2_DYRK2_ST	P04637	TP53	Q92630	DYRK2	S313	A307S	307	Missense	distal	-6	no	47.453	47.440	EPSD	COSMIC	45.963	Down-regulation
CMGC_DYRK_DYRK2_DYRK2_ST	P04637	TP53	Q92630	DYRK2	S313	P316S	316	Missense	distal	3	no	47.453	46.074	EPSD	COSMIC	45.963	Down-regulation
CMGC_DYRK_DYRK2_DYRK2_ST	P04637	TP53	Q92630	DYRK2	S314	S315P	315	Missense	proximal	1	no	30.031	59.432	EPSD	COSMIC	45.963	Gain
CMGC_DYRK_DYRK2_DYRK2_ST	P04637	TP53	Q92630	DYRK2	S315	N310T	310	Missense	distal	-5	no	59.350	58.384	EPSD	COSMIC	45.963	Down-regulation
CMGC_DYRK_DYRK2_DYRK2_ST	P04637	TP53	Q92630	DYRK2	S315	Q317R	317	Missense	proximal	2	no	59.350	58.895	EPSD	COSMIC	45.963	Down-regulation
CMGC_DYRK_DYRK2_DYRK2_ST	P04637	TP53	Q92630	DYRK2	S315	P309S	309	Missense	distal	-6	no	59.350	59.502	EPSD	COSMIC;GDSC;CCLE	45.963	Up-regulation
CMGC_DYRK_DYRK2_DYRK2_ST	P04637	TP53	Q92630	DYRK2	S315	K319E	319	Missense	distal	4	no	59.350	59.138	EPSD	COSMIC	45.963	Down-regulation
CMGC_DYRK_DYRK2_DYRK2_ST	P04637	TP53	Q92630	DYRK2	S315	P322L	322	Missense	distal	7	no	59.350	55.527	EPSD	COSMIC	45.963	Down-regulation
CMGC_DYRK_DYRK2_DYRK2_ST	P04637	TP53	Q92630	DYRK2	S315	K320N	320	Missense	distal	5	no	59.350	61.241	EPSD	COSMIC;GDSC;CCLE	45.963	Up-regulation
CMGC_DYRK_DYRK2_DYRK2_ST	P04637	TP53	Q92630	DYRK2	S315	N310L	310	Missense	distal	-5	no	59.350	59.256	EPSD	COSMIC	45.963	Down-regulation
CMGC_DYRK_DYRK2_DYRK2_ST	P04637	TP53	Q92630	DYRK2	S315	T312S	312	Missense	distal	-3	no	59.350	59.295	EPSD	COSMIC	45.963	Down-regulation
CMGC_DYRK_DYRK2_DYRK2_ST	P04637	TP53	Q92630	DYRK2	S315	N311Y	311	Missense	distal	-4	no	59.350	56.316	EPSD	COSMIC	45.963	Down-regulation
CMGC_DYRK_DYRK2_DYRK2_ST	P04637	TP53	Q92630	DYRK2	S315	P322R	322	Missense	distal	7	no	59.350	57.075	EPSD	COSMIC	45.963	Down-regulation
CMGC_DYRK_DYRK2_DYRK2_ST	P04637	TP53	Q92630	DYRK2	S315	N311K	311	Missense	distal	-4	no	59.350	56.687	EPSD	COSMIC	45.963	Down-regulation
CMGC_DYRK_DYRK2_DYRK2_ST	P04637	TP53	Q92630	DYRK2	S315	Q317K	317	Missense	proximal	2	no	59.350	58.753	EPSD	COSMIC	45.963	Down-regulation
CMGC_DYRK_DYRK2_DYRK2_ST	P04637	TP53	Q92630	DYRK2	S315	S315P	315	Missense	central	0	yes	59.350	0.000	EPSD	COSMIC	45.963	Loss
CMGC_DYRK_DYRK2_DYRK2_ST	P04637	TP53	Q92630	DYRK2	S315	N310H	310	Missense	distal	-5	no	59.350	59.949	EPSD	COSMIC	45.963	Up-regulation
CMGC_DYRK_DYRK2_DYRK2_ST	P04637	TP53	Q92630	DYRK2	S315	S314C	314	Missense	proximal	-1	no	59.350	57.316	EPSD	COSMIC	45.963	Down-regulation
CMGC_DYRK_DYRK2_DYRK2_ST	P04637	TP53	Q92630	DYRK2	S315	P318A	318	Missense	distal	3	no	59.350	56.468	EPSD	COSMIC	45.963	Down-regulation
CMGC_DYRK_DYRK2_DYRK2_ST	P04637	TP53	Q92630	DYRK2	S315	P316L	316	Missense	proximal	1	no	59.350	11.136	EPSD	COSMIC	45.963	Loss
CMGC_DYRK_DYRK2_DYRK2_ST	P04637	TP53	Q92630	DYRK2	S315	L308M	308	Missense	distal	-7	no	59.350	60.372	EPSD	COSMIC	45.963	Up-regulation
CMGC_DYRK_DYRK2_DYRK2_ST	P04637	TP53	Q92630	DYRK2	S315	S313C	313	Missense	proximal	-2	no	59.350	64.226	EPSD	COSMIC	45.963	Up-regulation
CMGC_DYRK_DYRK2_DYRK2_ST	P04637	TP53	Q92630	DYRK2	S315	N311H	311	Missense	distal	-4	no	59.350	53.112	EPSD	COSMIC	45.963	Down-regulation
CMGC_DYRK_DYRK2_DYRK2_ST	P04637	TP53	Q92630	DYRK2	S315	L308V	308	Missense	distal	-7	no	59.350	60.994	EPSD	COSMIC	45.963	Up-regulation
CMGC_DYRK_DYRK2_DYRK2_ST	P04637	TP53	Q92630	DYRK2	S315	S314F	314	Missense	proximal	-1	no	59.350	60.559	EPSD	COSMIC	45.963	Up-regulation
CMGC_DYRK_DYRK2_DYRK2_ST	P04637	TP53	Q92630	DYRK2	S315	K319R	319	Missense	distal	4	no	59.350	59.382	EPSD	COSMIC	45.963	Up-regulation
CMGC_DYRK_DYRK2_DYRK2_ST	P04637	TP53	Q92630	DYRK2	S315	T312A	312	Missense	distal	-3	no	59.350	62.098	EPSD	COSMIC	45.963	Up-regulation
CMGC_DYRK_DYRK2_DYRK2_ST	P04637	TP53	Q92630	DYRK2	S315	N310D	310	Missense	distal	-5	no	59.350	58.552	EPSD	COSMIC	45.963	Down-regulation
CMGC_DYRK_DYRK2_DYRK2_ST	P04637	TP53	Q92630	DYRK2	S315	N311D	311	Missense	distal	-4	no	59.350	59.464	EPSD	COSMIC	45.963	Up-regulation
CMGC_DYRK_DYRK2_DYRK2_ST	P04637	TP53	Q92630	DYRK2	S315	P309R	309	Missense	distal	-6	no	59.350	59.347	EPSD	COSMIC	45.963	Down-regulation
CMGC_DYRK_DYRK2_DYRK2_ST	P04637	TP53	Q92630	DYRK2	S315	S313N	313	Missense	proximal	-2	no	59.350	62.388	EPSD	COSMIC	45.963	Up-regulation
CMGC_DYRK_DYRK2_DYRK2_ST	P04637	TP53	Q92630	DYRK2	S315	Q317P	317	Missense	proximal	2	no	59.350	58.770	EPSD	COSMIC	45.963	Down-regulation
CMGC_DYRK_DYRK2_DYRK2_ST	P04637	TP53	Q92630	DYRK2	S315	P316S	316	Missense	proximal	1	no	59.350	29.949	EPSD	COSMIC	45.963	Loss
CMGC_DYRK_DYRK2_DYRK2_ST	P04637	TP53	Q92630	DYRK2	S366	S367F	367	Missense	proximal	1	no	53.248	20.951	EPSD	COSMIC	45.963	Loss
CMGC_DYRK_DYRK2_DYRK2_ST	P04637	TP53	Q92630	DYRK2	S366	K370N	370	Missense	distal	4	no	53.248	53.308	EPSD	COSMIC	45.963	Up-regulation
CMGC_DYRK_DYRK2_DYRK2_ST	P04637	TP53	Q92630	DYRK2	S366	G361E	361	Missense	distal	-5	no	53.248	52.846	EPSD	COSMIC	45.963	Down-regulation
CMGC_DYRK_DYRK2_DYRK2_ST	P04637	TP53	Q92630	DYRK2	S366	P359S	359	Missense	distal	-7	no	53.248	52.025	EPSD	COSMIC	45.963	Down-regulation
CMGC_DYRK_DYRK2_DYRK2_ST	P04637	TP53	Q92630	DYRK2	S366	A364D	364	Missense	proximal	-2	no	53.248	56.326	EPSD	COSMIC	45.963	Up-regulation
CMGC_DYRK_DYRK2_DYRK2_ST	P04637	TP53	Q92630	DYRK2	S366	H365Y	365	Missense	proximal	-1	no	53.248	51.902	EPSD	COSMIC	45.963	Down-regulation
CMGC_DYRK_DYRK2_DYRK2_ST	P04637	TP53	Q92630	DYRK2	S366	G360A	360	Missense	distal	-6	no	53.248	53.254	EPSD	COSMIC	45.963	Up-regulation
CMGC_DYRK_DYRK2_DYRK2_ST	P04637	TP53	Q92630	DYRK2	S366	A364T	364	Missense	proximal	-2	no	53.248	52.938	EPSD	COSMIC	45.963	Down-regulation
CMGC_DYRK_DYRK2_DYRK2_ST	P04637	TP53	Q92630	DYRK2	S366	S366A	366	Missense	central	0	yes	53.248	0.000	EPSD	COSMIC	45.963	Loss
CMGC_DYRK_DYRK2_DYRK2_ST	P04637	TP53	Q92630	DYRK2	S366	G361R	361	Missense	distal	-5	no	53.248	52.218	EPSD	COSMIC	45.963	Down-regulation
CMGC_DYRK_DYRK2_DYRK2_ST	P04637	TP53	Q92630	DYRK2	S366	K370Q	370	Missense	distal	4	no	53.248	53.249	EPSD	COSMIC	45.963	Up-regulation
CMGC_DYRK_DYRK2_DYRK2_ST	P04637	TP53	Q92630	DYRK2	S366	K373R	373	Missense	distal	7	no	53.248	52.352	EPSD	COSMIC	45.963	Down-regulation
CMGC_DYRK_DYRK2_DYRK2_ST	P04637	TP53	Q92630	DYRK2	S366	S371P	371	Missense	distal	5	no	53.248	53.703	EPSD	COSMIC	45.963	Up-regulation
CMGC_DYRK_DYRK2_DYRK2_ST	P04637	TP53	Q92630	DYRK2	S376	K373R	373	Missense	distal	-3	no	35.344	48.549	EPSD	COSMIC	45.963	Gain
CMGC_DYRK_DYRK2_DYRK2_ST	P04637	TP53	Q92630	DYRK2	S378	R379P	379	Missense	proximal	1	no	-2.262	54.128	EPSD	COSMIC	45.963	Gain
CMGC_DYRK_DYRK2_DYRK2_ST	Q14195	DPYSL3	Q92630	DYRK2	S257	L250F	250	Missense	distal	-7	no	46.949	46.443	EPSD	COSMIC	45.963	Down-regulation
CMGC_DYRK_DYRK2_DYRK2_ST	Q14195	DPYSL3	Q92630	DYRK2	S363	E360D	360	Missense	distal	-3	no	61.818	65.895	EPSD	COSMIC	45.963	Up-regulation
CMGC_DYRK_DYRK2_DYRK2_ST	Q14195	DPYSL3	Q92630	DYRK2	S363	V364A	364	Missense	proximal	1	no	61.818	-2.644	EPSD	COSMIC	45.963	Loss
CMGC_DYRK_DYRK2_DYRK2_ST	Q14195	DPYSL3	Q92630	DYRK2	S363	A369V	369	Missense	distal	6	no	61.818	62.212	EPSD	COSMIC	45.963	Up-regulation
CMGC_DYRK_DYRK2_DYRK2_ST	Q14195	DPYSL3	Q92630	DYRK2	S363	S363F	363	Missense	central	0	yes	61.818	0.000	EPSD	COSMIC	45.963	Loss
CMGC_DYRK_DYRK2_DYRK2_ST	Q14195	DPYSL3	Q92630	DYRK2	T509	A516T	516	Missense	distal	7	no	56.305	58.777	EPSD	COSMIC;GDSC;CCLE	45.963	Up-regulation
CMGC_DYRK_DYRK2_DYRK2_ST	Q14195	DPYSL3	Q92630	DYRK2	T514	R520Q	520	Missense	distal	6	no	52.124	52.493	EPSD	COSMIC	45.963	Up-regulation
CMGC_DYRK_DYRK2_DYRK2_ST	Q14195	DPYSL3	Q92630	DYRK2	T514	A516T	516	Missense	proximal	2	no	52.124	51.854	EPSD	COSMIC;GDSC;CCLE	45.963	Down-regulation
CMGC_DYRK_DYRK2_DYRK2_ST	Q14195	DPYSL3	Q92630	DYRK2	S522	R525Q	525	Missense	distal	3	no	87.074	86.061	PhosphoSitePlus	COSMIC;GDSC;CCLE	45.963	Down-regulation
CMGC_DYRK_DYRK2_DYRK2_ST	Q14195	DPYSL3	Q92630	DYRK2	S522	R520Q	520	Missense	proximal	-2	no	87.074	79.368	PhosphoSitePlus	COSMIC	45.963	Down-regulation
CMGC_DYRK_DYRK2_DYRK2_ST	Q14195	DPYSL3	Q92630	DYRK2	S522	A516T	516	Missense	distal	-6	no	87.074	86.889	PhosphoSitePlus	COSMIC;GDSC;CCLE	45.963	Down-regulation
CMGC_DYRK_DYRK2_DYRK2_ST	Q14195	DPYSL3	Q92630	DYRK2	S522	P529H	529	Missense	distal	7	no	87.074	79.679	PhosphoSitePlus	COSMIC	45.963	Down-regulation
CMGC_DYRK_DYRK2_DYRK2_ST	Q14195	DPYSL3	Q92630	DYRK2	S553	G548W	548	Missense	distal	-5	no	62.987	62.357	EPSD	COSMIC	45.963	Down-regulation
CMGC_DYRK_DYRK2_DYRK2_ST	Q16555	DPYSL2	Q92630	DYRK2	S304	A298T	298	Missense	distal	-6	no	55.536	55.352	EPSD	COSMIC	45.963	Down-regulation
CMGC_DYRK_DYRK2_DYRK2_ST	Q16555	DPYSL2	Q92630	DYRK2	S304	P305L	305	Missense	proximal	1	no	55.536	7.322	EPSD	COSMIC	45.963	Loss
CMGC_DYRK_DYRK2_DYRK2_ST	Q16555	DPYSL2	Q92630	DYRK2	S304	P305T	305	Missense	proximal	1	no	55.536	33.461	EPSD	COSMIC	45.963	Loss
CMGC_DYRK_DYRK2_DYRK2_ST	Q16555	DPYSL2	Q92630	DYRK2	S304	V302F	302	Missense	proximal	-2	no	55.536	42.883	EPSD	COSMIC	45.963	Loss
CMGC_DYRK_DYRK2_DYRK2_ST	Q16555	DPYSL2	Q92630	DYRK2	S304	L307S	307	Missense	distal	3	no	55.536	55.929	EPSD	COSMIC	45.963	Up-regulation
CMGC_DYRK_DYRK2_DYRK2_ST	Q16555	DPYSL2	Q92630	DYRK2	S308	P305L	305	Missense	distal	-3	no	47.734	46.467	EPSD	COSMIC	45.963	Down-regulation
CMGC_DYRK_DYRK2_DYRK2_ST	Q16555	DPYSL2	Q92630	DYRK2	S308	P305T	305	Missense	distal	-3	no	47.734	45.100	EPSD	COSMIC	45.963	Loss
CMGC_DYRK_DYRK2_DYRK2_ST	Q16555	DPYSL2	Q92630	DYRK2	S308	V302F	302	Missense	distal	-6	no	47.734	48.176	EPSD	COSMIC	45.963	Up-regulation
CMGC_DYRK_DYRK2_DYRK2_ST	Q16555	DPYSL2	Q92630	DYRK2	S308	L307S	307	Missense	proximal	-1	no	47.734	47.478	EPSD	COSMIC	45.963	Down-regulation
CMGC_DYRK_DYRK2_DYRK2_ST	Q16555	DPYSL2	Q92630	DYRK2	S363	R361Q	361	Missense	proximal	-2	no	52.089	44.383	EPSD	COSMIC	45.963	Loss
CMGC_DYRK_DYRK2_DYRK2_ST	Q16555	DPYSL2	Q92630	DYRK2	S363	D367N	367	Missense	distal	4	no	52.089	52.087	EPSD	COSMIC	45.963	Down-regulation
CMGC_DYRK_DYRK2_DYRK2_ST	Q16555	DPYSL2	Q92630	DYRK2	S416	V410I	410	Missense	distal	-6	no	49.689	49.941	EPSD	COSMIC	45.963	Up-regulation
CMGC_DYRK_DYRK2_DYRK2_ST	Q16555	DPYSL2	Q92630	DYRK2	S416	V417I	417	Missense	proximal	1	no	49.689	13.406	EPSD	COSMIC	45.963	Loss
CMGC_DYRK_DYRK2_DYRK2_ST	Q16555	DPYSL2	Q92630	DYRK2	S416	D415N	415	Missense	proximal	-1	no	49.689	49.932	EPSD	COSMIC;CCLE	45.963	Up-regulation
CMGC_DYRK_DYRK2_DYRK2_ST	Q16555	DPYSL2	Q92630	DYRK2	S442	G436C	436	Missense	distal	-6	no	47.760	47.364	EPSD	COSMIC;GDSC;CCLE	45.963	Down-regulation
CMGC_DYRK_DYRK2_DYRK2_ST	Q16555	DPYSL2	Q92630	DYRK2	S442	V446I	446	Missense	distal	4	no	47.760	47.659	EPSD	COSMIC	45.963	Down-regulation
CMGC_DYRK_DYRK2_DYRK2_ST	Q16555	DPYSL2	Q92630	DYRK2	S442	S448N	448	Missense	distal	6	no	47.760	48.042	EPSD	COSMIC;GDSC;CCLE	45.963	Up-regulation
CMGC_DYRK_DYRK2_DYRK2_ST	Q16555	DPYSL2	Q92630	DYRK2	T509	V506A	506	Missense	distal	-3	no	56.167	61.376	EPSD	COSMIC	45.963	Up-regulation
CMGC_DYRK_DYRK2_DYRK2_ST	Q16555	DPYSL2	Q92630	DYRK2	T512	V506A	506	Missense	distal	-6	no	58.024	58.262	EPSD	COSMIC	45.963	Up-regulation
CMGC_DYRK_DYRK2_DYRK2_ST	Q16555	DPYSL2	Q92630	DYRK2	S537	L534F	534	Missense	distal	-3	no	47.827	38.649	EPSD	COSMIC	45.963	Loss
CMGC_DYRK_DYRK2_DYRK2_ST	Q16555	DPYSL2	Q92630	DYRK2	S537	R532Q	532	Missense	distal	-5	no	47.827	47.688	EPSD	COSMIC;GDSC;CCLE	45.963	Down-regulation
CMGC_DYRK_DYRK2_DYRK2_ST	Q16555	DPYSL2	Q92630	DYRK2	S537	G538E	538	Missense	proximal	1	no	47.827	-42.967	EPSD	COSMIC	45.963	Loss
CMGC_DYRK_DYRK2_DYRK2_ST	Q16555	DPYSL2	Q92630	DYRK2	S537	G543D	543	Missense	distal	6	no	47.827	47.944	EPSD	COSMIC;GDSC	45.963	Up-regulation
CMGC_DYRK_DYRK2_DYRK2_ST	Q16555	DPYSL2	Q92630	DYRK2	T555	N549S	549	Missense	distal	-6	no	49.385	49.623	EPSD	COSMIC	45.963	Up-regulation
CMGC_DYRK_DYRK2_DYRK2_ST	Q16555	DPYSL2	Q92630	DYRK2	T555	P561L	561	Missense	distal	6	no	49.385	48.901	EPSD	COSMIC	45.963	Down-regulation
CMGC_DYRK_DYRK2_DYRK2_ST	Q16555	DPYSL2	Q92630	DYRK2	T555	R557C	557	Missense	proximal	2	no	49.385	50.240	EPSD	COSMIC	45.963	Up-regulation
CMGC_DYRK_DYRK2_DYRK2_ST	Q16555	DPYSL2	Q92630	DYRK2	T555	P561F	561	Missense	distal	6	no	49.385	48.794	EPSD	COSMIC	45.963	Down-regulation
CMGC_DYRK_DYRK2_DYRK2_ST	Q16555	DPYSL2	Q92630	DYRK2	T555	R557H	557	Missense	proximal	2	no	49.385	48.472	EPSD	COSMIC	45.963	Down-regulation
CMGC_DYRK_DYRK2_DYRK2_ST	P10636	MAPT	Q92630	DYRK2	S61	E62K	62	Missense	proximal	1	no	-47.686	48.096	EPSD	COSMIC	45.963	Gain
CMGC_DYRK_DYRK2_DYRK2_ST	P10636	MAPT	Q92630	DYRK2	S68	E62K	62	Missense	distal	-6	no	50.190	49.916	EPSD	COSMIC	45.963	Down-regulation
CMGC_DYRK_DYRK2_DYRK2_ST	P10636	MAPT	Q92630	DYRK2	T69	E62K	62	Missense	distal	-7	no	53.844	55.773	EPSD	COSMIC	45.963	Up-regulation
CMGC_DYRK_DYRK2_DYRK2_ST	P10636	MAPT	Q92630	DYRK2	T111	G107R	107	Missense	distal	-4	no	37.489	48.674	EPSD	COSMIC	45.963	Gain
CMGC_DYRK_DYRK2_DYRK2_ST	P10636	MAPT	Q92630	DYRK2	S171	G172V	172	Missense	proximal	1	no	44.056	57.208	EPSD	COSMIC	45.963	Gain
CMGC_DYRK_DYRK2_DYRK2_ST	P10636	MAPT	Q92630	DYRK2	S214	E210Q	210	Missense	distal	-4	no	65.937	70.019	EPSD	COSMIC	45.963	Up-regulation
CMGC_DYRK_DYRK2_DYRK2_ST	P10636	MAPT	Q92630	DYRK2	S214	G207E	207	Missense	distal	-7	no	65.937	64.555	EPSD	COSMIC	45.963	Down-regulation
CMGC_DYRK_DYRK2_DYRK2_ST	P10636	MAPT	Q92630	DYRK2	S228	E226K	226	Missense	proximal	-2	no	37.761	46.452	EPSD	COSMIC	45.963	Gain
CMGC_DYRK_DYRK2_DYRK2_ST	P10636	MAPT	Q92630	DYRK2	S232	Q230R	230	Missense	proximal	-2	no	43.040	50.746	EPSD	COSMIC	45.963	Gain
CMGC_DYRK_DYRK2_DYRK2_ST	P10636	MAPT	Q92630	DYRK2	S235	A237T	237	Missense	proximal	2	no	48.540	48.271	EPSD	COSMIC	45.963	Down-regulation
CMGC_DYRK_DYRK2_DYRK2_ST	P10636	MAPT	Q92630	DYRK2	S235	A240S	240	Missense	distal	5	no	48.540	48.152	EPSD	COSMIC	45.963	Down-regulation
CMGC_DYRK_DYRK2_DYRK2_ST	P10636	MAPT	Q92630	DYRK2	S235	D242N	242	Missense	distal	7	no	48.540	49.084	EPSD	COSMIC	45.963	Up-regulation
CMGC_DYRK_DYRK2_DYRK2_ST	P10636	MAPT	Q92630	DYRK2	S235	Q230R	230	Missense	distal	-5	no	48.540	48.679	EPSD	COSMIC	45.963	Up-regulation
CMGC_DYRK_DYRK2_DYRK2_ST	P10636	MAPT	Q92630	DYRK2	S235	S238P	238	Missense	distal	3	no	48.540	49.920	EPSD	COSMIC	45.963	Up-regulation
CMGC_DYRK_DYRK2_DYRK2_ST	P10636	MAPT	Q92630	DYRK2	S235	P233S	233	Missense	proximal	-2	no	48.540	45.852	EPSD	COSMIC	45.963	Loss
CMGC_DYRK_DYRK2_DYRK2_ST	P10636	MAPT	Q92630	DYRK2	S235	S238F	238	Missense	distal	3	no	48.540	47.124	EPSD	COSMIC	45.963	Down-regulation
CMGC_DYRK_DYRK2_DYRK2_ST	P10636	MAPT	Q92630	DYRK2	S235	S235L	235	Missense	central	0	yes	48.540	0.000	EPSD	COSMIC	45.963	Loss
CMGC_DYRK_DYRK2_DYRK2_ST	P10636	MAPT	Q92630	DYRK2	S238	A237T	237	Missense	proximal	-1	no	53.612	52.763	EPSD	COSMIC	45.963	Down-regulation
CMGC_DYRK_DYRK2_DYRK2_ST	P10636	MAPT	Q92630	DYRK2	S238	A240S	240	Missense	proximal	2	no	53.612	53.247	EPSD	COSMIC	45.963	Down-regulation
CMGC_DYRK_DYRK2_DYRK2_ST	P10636	MAPT	Q92630	DYRK2	S238	D242N	242	Missense	distal	4	no	53.612	53.610	EPSD	COSMIC	45.963	Down-regulation
CMGC_DYRK_DYRK2_DYRK2_ST	P10636	MAPT	Q92630	DYRK2	S238	R244W	244	Missense	distal	6	no	53.612	53.638	EPSD	COSMIC	45.963	Up-regulation
CMGC_DYRK_DYRK2_DYRK2_ST	P10636	MAPT	Q92630	DYRK2	S238	S238P	238	Missense	central	0	yes	53.612	0.000	EPSD	COSMIC	45.963	Loss
CMGC_DYRK_DYRK2_DYRK2_ST	P10636	MAPT	Q92630	DYRK2	S238	P233S	233	Missense	distal	-5	no	53.612	54.756	EPSD	COSMIC	45.963	Up-regulation
CMGC_DYRK_DYRK2_DYRK2_ST	P10636	MAPT	Q92630	DYRK2	S238	S238F	238	Missense	central	0	yes	53.612	0.000	EPSD	COSMIC	45.963	Loss
CMGC_DYRK_DYRK2_DYRK2_ST	P10636	MAPT	Q92630	DYRK2	S238	G243D	243	Missense	distal	5	no	53.612	56.031	EPSD	COSMIC	45.963	Up-regulation
CMGC_DYRK_DYRK2_DYRK2_ST	P10636	MAPT	Q92630	DYRK2	S238	S235L	235	Missense	distal	-3	no	53.612	55.033	EPSD	COSMIC	45.963	Up-regulation
CMGC_DYRK_DYRK2_DYRK2_ST	P10636	MAPT	Q92630	DYRK2	S411	L410F	410	Missense	proximal	-1	no	70.167	71.120	EPSD	COSMIC	45.963	Up-regulation
CMGC_DYRK_DYRK2_DYRK2_ST	P10636	MAPT	Q92630	DYRK2	S411	P412S	412	Missense	proximal	1	no	70.167	40.767	EPSD	COSMIC	45.963	Loss
CMGC_DYRK_DYRK2_DYRK2_ST	P10636	MAPT	Q92630	DYRK2	T416	L410F	410	Missense	distal	-6	no	50.510	50.560	EPSD	COSMIC	45.963	Up-regulation
CMGC_DYRK_DYRK2_DYRK2_ST	P10636	MAPT	Q92630	DYRK2	T416	P412S	412	Missense	distal	-4	no	50.510	51.778	EPSD	COSMIC	45.963	Up-regulation
CMGC_DYRK_DYRK2_DYRK2_ST	P10636	MAPT	Q92630	DYRK2	S438	S443Y	443	Missense	distal	5	no	65.359	65.981	EPSD	COSMIC	45.963	Up-regulation
CMGC_DYRK_DYRK2_DYRK2_ST	P10636	MAPT	Q92630	DYRK2	T470	T466M	466	Missense	distal	-4	no	54.038	58.057	EPSD	COSMIC;GDSC;CCLE	45.963	Up-regulation
CMGC_DYRK_DYRK2_DYRK2_ST	P10636	MAPT	Q92630	DYRK2	T470	K467T	467	Missense	distal	-3	no	54.038	51.388	EPSD	COSMIC	45.963	Down-regulation
CMGC_DYRK_DYRK2_DYRK2_ST	P10636	MAPT	Q92630	DYRK2	T470	P477L	477	Missense	distal	7	no	54.038	50.215	EPSD	COSMIC	45.963	Down-regulation
CMGC_DYRK_DYRK2_DYRK2_ST	P10636	MAPT	Q92630	DYRK2	T470	P477S	477	Missense	distal	7	no	54.038	50.982	EPSD	COSMIC	45.963	Down-regulation
CMGC_DYRK_DYRK2_DYRK2_ST	P10636	MAPT	Q92630	DYRK2	T486	R487K	487	Missense	proximal	1	no	8.703	48.897	EPSD	COSMIC	45.963	Gain
CMGC_DYRK_DYRK2_DYRK2_ST	P10636	MAPT	Q92630	DYRK2	T492	R487K	487	Missense	distal	-5	no	58.390	58.198	EPSD	COSMIC	45.963	Down-regulation
CMGC_DYRK_DYRK2_DYRK2_ST	P10636	MAPT	Q92630	DYRK2	T492	K491R	491	Missense	proximal	-1	no	58.390	58.086	EPSD	COSMIC	45.963	Down-regulation
CMGC_DYRK_DYRK2_DYRK2_ST	P10636	MAPT	Q92630	DYRK2	T492	R487G	487	Missense	distal	-5	no	58.390	59.421	EPSD	COSMIC	45.963	Up-regulation
CMGC_DYRK_DYRK2_DYRK2_ST	P10636	MAPT	Q92630	DYRK2	T492	A495T	495	Missense	distal	3	no	58.390	60.700	EPSD	COSMIC	45.963	Up-regulation
CMGC_DYRK_DYRK2_DYRK2_ST	P10636	MAPT	Q92630	DYRK2	T492	P493L	493	Missense	proximal	1	no	58.390	10.176	EPSD	COSMIC	45.963	Loss
CMGC_DYRK_DYRK2_DYRK2_ST	P10636	MAPT	Q92630	DYRK2	T498	K491R	491	Missense	distal	-7	no	56.812	55.839	EPSD	COSMIC	45.963	Down-regulation
CMGC_DYRK_DYRK2_DYRK2_ST	P10636	MAPT	Q92630	DYRK2	T498	A495T	495	Missense	distal	-3	no	56.812	54.063	EPSD	COSMIC	45.963	Down-regulation
CMGC_DYRK_DYRK2_DYRK2_ST	P10636	MAPT	Q92630	DYRK2	T498	P493L	493	Missense	distal	-5	no	56.812	58.051	EPSD	COSMIC	45.963	Up-regulation
CMGC_DYRK_DYRK2_DYRK2_ST	P10636	MAPT	Q92630	DYRK2	S508	P506S	506	Missense	proximal	-2	no	55.358	52.670	EPSD	COSMIC	45.963	Down-regulation
CMGC_DYRK_DYRK2_DYRK2_ST	P10636	MAPT	Q92630	DYRK2	S508	R511C	511	Missense	distal	3	no	55.358	54.701	EPSD	COSMIC;CCLE	45.963	Down-regulation
CMGC_DYRK_DYRK2_DYRK2_ST	P10636	MAPT	Q92630	DYRK2	S508	G509V	509	Missense	proximal	1	no	55.358	68.510	EPSD	COSMIC	45.963	Up-regulation
CMGC_DYRK_DYRK2_DYRK2_ST	P10636	MAPT	Q92630	DYRK2	S508	P506L	506	Missense	proximal	-2	no	55.358	48.296	EPSD	COSMIC	45.963	Down-regulation
CMGC_DYRK_DYRK2_DYRK2_ST	P10636	MAPT	Q92630	DYRK2	S519	G521V	521	Missense	proximal	2	no	57.632	58.084	EPSD	COSMIC	45.963	Up-regulation
CMGC_DYRK_DYRK2_DYRK2_ST	P10636	MAPT	Q92630	DYRK2	S519	R526H	526	Missense	distal	7	no	57.632	52.511	EPSD	COSMIC	45.963	Down-regulation
CMGC_DYRK_DYRK2_DYRK2_ST	P10636	MAPT	Q92630	DYRK2	S519	G518V	518	Missense	proximal	-1	no	57.632	57.271	EPSD	COSMIC	45.963	Down-regulation
CMGC_DYRK_DYRK2_DYRK2_ST	P10636	MAPT	Q92630	DYRK2	T522	G521V	521	Missense	proximal	-1	no	60.523	60.163	EPSD	COSMIC	45.963	Down-regulation
CMGC_DYRK_DYRK2_DYRK2_ST	P10636	MAPT	Q92630	DYRK2	T522	R526H	526	Missense	distal	4	no	60.523	60.185	EPSD	COSMIC	45.963	Down-regulation
CMGC_DYRK_DYRK2_DYRK2_ST	P10636	MAPT	Q92630	DYRK2	T522	G518V	518	Missense	distal	-4	no	60.523	65.078	EPSD	COSMIC	45.963	Up-regulation
CMGC_DYRK_DYRK2_DYRK2_ST	P10636	MAPT	Q92630	DYRK2	T522	R528S	528	Missense	distal	6	no	60.523	60.472	EPSD	COSMIC	45.963	Down-regulation
CMGC_DYRK_DYRK2_DYRK2_ST	P10636	MAPT	Q92630	DYRK2	T529	R526H	526	Missense	distal	-3	no	87.937	68.160	EPSD	COSMIC	45.963	Down-regulation
CMGC_DYRK_DYRK2_DYRK2_ST	P10636	MAPT	Q92630	DYRK2	T529	R528S	528	Missense	proximal	-1	no	87.937	88.978	EPSD	COSMIC	45.963	Up-regulation
CMGC_DYRK_DYRK2_DYRK2_ST	P10636	MAPT	Q92630	DYRK2	T529	P530S	530	Missense	proximal	1	no	87.937	58.537	EPSD	COSMIC	45.963	Down-regulation
CMGC_DYRK_DYRK2_DYRK2_ST	P10636	MAPT	Q92630	DYRK2	T529	P536H	536	Missense	distal	7	no	87.937	80.542	EPSD	COSMIC	45.963	Down-regulation
CMGC_DYRK_DYRK2_DYRK2_ST	P10636	MAPT	Q92630	DYRK2	T529	P535Q	535	Missense	distal	6	no	87.937	88.086	EPSD	COSMIC	45.963	Up-regulation
CMGC_DYRK_DYRK2_DYRK2_ST	P10636	MAPT	Q92630	DYRK2	T534	R528S	528	Missense	distal	-6	no	51.057	51.212	EPSD	COSMIC	45.963	Up-regulation
CMGC_DYRK_DYRK2_DYRK2_ST	P10636	MAPT	Q92630	DYRK2	T534	P530S	530	Missense	distal	-4	no	51.057	52.325	EPSD	COSMIC	45.963	Up-regulation
CMGC_DYRK_DYRK2_DYRK2_ST	P10636	MAPT	Q92630	DYRK2	T534	P536H	536	Missense	proximal	2	no	51.057	50.269	EPSD	COSMIC	45.963	Down-regulation
CMGC_DYRK_DYRK2_DYRK2_ST	P10636	MAPT	Q92630	DYRK2	T534	P535Q	535	Missense	proximal	1	no	51.057	6.183	EPSD	COSMIC	45.963	Loss
CMGC_DYRK_DYRK2_DYRK2_ST	P10636	MAPT	Q92630	DYRK2	T534	E539Q	539	Missense	distal	5	no	51.057	52.155	EPSD	COSMIC	45.963	Up-regulation
CMGC_DYRK_DYRK2_DYRK2_ST	P10636	MAPT	Q92630	DYRK2	T548	P550S	550	Missense	proximal	2	no	57.713	57.200	EPSD	COSMIC	45.963	Down-regulation
CMGC_DYRK_DYRK2_DYRK2_ST	P10636	MAPT	Q92630	DYRK2	T548	P553R	553	Missense	distal	5	no	57.713	59.743	EPSD	COSMIC	45.963	Up-regulation
CMGC_DYRK_DYRK2_DYRK2_ST	P10636	MAPT	Q92630	DYRK2	T548	P553L	553	Missense	distal	5	no	57.713	56.771	EPSD	COSMIC	45.963	Down-regulation
CMGC_DYRK_DYRK2_DYRK2_ST	P10636	MAPT	Q92630	DYRK2	T548	P549L	549	Missense	proximal	1	no	57.713	9.499	EPSD	COSMIC	45.963	Loss
CMGC_DYRK_DYRK2_DYRK2_ST	P10636	MAPT	Q92630	DYRK2	T548	S555F	555	Missense	distal	7	no	57.713	55.174	EPSD	COSMIC	45.963	Down-regulation
CMGC_DYRK_DYRK2_DYRK2_ST	P10636	MAPT	Q92630	DYRK2	T548	P553Q	553	Missense	distal	5	no	57.713	58.957	EPSD	COSMIC	45.963	Up-regulation
CMGC_DYRK_DYRK2_DYRK2_ST	P10636	MAPT	Q92630	DYRK2	S552	P550S	550	Missense	proximal	-2	no	62.365	59.677	EPSD	COSMIC	45.963	Down-regulation
CMGC_DYRK_DYRK2_DYRK2_ST	P10636	MAPT	Q92630	DYRK2	S552	R559C	559	Missense	distal	7	no	62.365	63.219	EPSD	COSMIC	45.963	Up-regulation
CMGC_DYRK_DYRK2_DYRK2_ST	P10636	MAPT	Q92630	DYRK2	S552	P553R	553	Missense	proximal	1	no	62.365	5.976	EPSD	COSMIC	45.963	Loss
CMGC_DYRK_DYRK2_DYRK2_ST	P10636	MAPT	Q92630	DYRK2	S552	P553L	553	Missense	proximal	1	no	62.365	14.151	EPSD	COSMIC	45.963	Loss
CMGC_DYRK_DYRK2_DYRK2_ST	P10636	MAPT	Q92630	DYRK2	S552	P549L	549	Missense	distal	-3	no	62.365	61.099	EPSD	COSMIC	45.963	Down-regulation
CMGC_DYRK_DYRK2_DYRK2_ST	P10636	MAPT	Q92630	DYRK2	S552	S555F	555	Missense	distal	3	no	62.365	60.948	EPSD	COSMIC	45.963	Down-regulation
CMGC_DYRK_DYRK2_DYRK2_ST	P10636	MAPT	Q92630	DYRK2	S552	P553Q	553	Missense	proximal	1	no	62.365	17.491	EPSD	COSMIC	45.963	Loss
CMGC_DYRK_DYRK2_DYRK2_ST	P10636	MAPT	Q92630	DYRK2	S575	T580N	580	Missense	distal	5	no	46.233	47.271	EPSD	COSMIC	45.963	Up-regulation
CMGC_DYRK_DYRK2_DYRK2_ST	P10636	MAPT	Q92630	DYRK2	S575	G578S	578	Missense	distal	3	no	46.233	46.019	EPSD	COSMIC	45.963	Down-regulation
CMGC_DYRK_DYRK2_DYRK2_ST	P10636	MAPT	Q92630	DYRK2	S575	K571E	571	Missense	distal	-4	no	46.233	45.264	EPSD	COSMIC	45.963	Loss
CMGC_DYRK_DYRK2_DYRK2_ST	P10636	MAPT	Q92630	DYRK2	S575	P568S	568	Missense	distal	-7	no	46.233	45.009	EPSD	COSMIC	45.963	Loss
CMGC_DYRK_DYRK2_DYRK2_ST	P10636	MAPT	Q92630	DYRK2	S606	N613D	613	Missense	distal	7	no	51.966	51.423	EPSD	COSMIC	45.963	Down-regulation
CMGC_DYRK_DYRK2_DYRK2_ST	P10636	MAPT	Q92630	DYRK2	S606	S602G	602	Missense	distal	-4	no	51.966	45.501	EPSD	COSMIC	45.963	Loss
CMGC_DYRK_DYRK2_DYRK2_ST	P10636	MAPT	Q92630	DYRK2	S606	C608W	608	Missense	proximal	2	no	51.966	50.636	EPSD	COSMIC	45.963	Down-regulation
CMGC_DYRK_DYRK2_DYRK2_ST	P10636	MAPT	Q92630	DYRK2	S606	S610L	610	Missense	distal	4	no	51.966	51.884	EPSD	COSMIC	45.963	Down-regulation
CMGC_DYRK_DYRK2_DYRK2_ST	P10636	MAPT	Q92630	DYRK2	S606	D600E	600	Missense	distal	-6	no	51.966	52.039	EPSD	COSMIC	45.963	Up-regulation
CMGC_DYRK_DYRK2_DYRK2_ST	P10636	MAPT	Q92630	DYRK2	S610	N613D	613	Missense	distal	3	no	58.066	58.348	EPSD	COSMIC	45.963	Up-regulation
CMGC_DYRK_DYRK2_DYRK2_ST	P10636	MAPT	Q92630	DYRK2	S610	C608W	608	Missense	proximal	-2	no	58.066	51.561	EPSD	COSMIC	45.963	Down-regulation
CMGC_DYRK_DYRK2_DYRK2_ST	P10636	MAPT	Q92630	DYRK2	S610	S610L	610	Missense	central	0	yes	58.066	0.000	EPSD	COSMIC	45.963	Loss
CMGC_DYRK_DYRK2_DYRK2_ST	P10636	MAPT	Q92630	DYRK2	S637	S633N	633	Missense	distal	-4	no	55.913	59.436	EPSD	COSMIC	45.963	Up-regulation
CMGC_DYRK_DYRK2_DYRK2_ST	P10636	MAPT	Q92630	DYRK2	S637	S633I	633	Missense	distal	-4	no	55.913	52.282	EPSD	COSMIC	45.963	Down-regulation
CMGC_DYRK_DYRK2_DYRK2_ST	P10636	MAPT	Q92630	DYRK2	S669	S669L	669	Missense	central	0	yes	57.738	0.000	EPSD	COSMIC	45.963	Loss
CMGC_DYRK_DYRK2_DYRK2_ST	P10636	MAPT	Q92630	DYRK2	S669	R666K	666	Missense	distal	-3	no	57.738	44.533	EPSD	COSMIC	45.963	Loss
CMGC_DYRK_DYRK2_DYRK2_ST	P10636	MAPT	Q92630	DYRK2	S669	D662G	662	Missense	distal	-7	no	57.738	57.226	EPSD	COSMIC	45.963	Down-regulation
CMGC_DYRK_DYRK2_DYRK2_ST	P10636	MAPT	Q92630	DYRK2	S669	S673F	673	Missense	distal	4	no	57.738	57.515	EPSD	COSMIC	45.963	Down-regulation
CMGC_DYRK_DYRK2_DYRK2_ST	P10636	MAPT	Q92630	DYRK2	S669	K670N	670	Missense	proximal	1	no	57.738	44.351	EPSD	COSMIC	45.963	Loss
CMGC_DYRK_DYRK2_DYRK2_ST	P10636	MAPT	Q92630	DYRK2	S669	K664N	664	Missense	distal	-5	no	57.738	58.752	EPSD	COSMIC	45.963	Up-regulation
CMGC_DYRK_DYRK2_DYRK2_ST	P10636	MAPT	Q92630	DYRK2	S669	L674Q	674	Missense	distal	5	no	57.738	59.923	EPSD	COSMIC	45.963	Up-regulation
CMGC_DYRK_DYRK2_DYRK2_ST	P10636	MAPT	Q92630	DYRK2	S721	R723W	723	Missense	proximal	2	no	53.193	52.718	EPSD	COSMIC	45.963	Down-regulation
CMGC_DYRK_DYRK2_DYRK2_ST	P10636	MAPT	Q92630	DYRK2	S721	V728M	728	Missense	distal	7	no	53.193	51.677	EPSD	COSMIC	45.963	Down-regulation
CMGC_DYRK_DYRK2_DYRK2_ST	P10636	MAPT	Q92630	DYRK2	S721	V728A	728	Missense	distal	7	no	53.193	50.317	EPSD	COSMIC	45.963	Down-regulation
CMGC_DYRK_DYRK2_DYRK2_ST	P10636	MAPT	Q92630	DYRK2	S739	G732S	732	Missense	distal	-7	no	67.423	67.208	EPSD	COSMIC	45.963	Down-regulation
CMGC_DYRK_DYRK2_DYRK2_ST	P10636	MAPT	Q92630	DYRK2	S739	D735N	735	Missense	distal	-4	no	67.423	67.309	EPSD	COSMIC	45.963	Down-regulation
CMGC_DYRK_DYRK2_DYRK2_ST	P10636	MAPT	Q92630	DYRK2	S739	G732C	732	Missense	distal	-7	no	67.423	68.317	EPSD	COSMIC	45.963	Up-regulation
CMGC_DYRK_DYRK2_DYRK2_ST	P10636	MAPT	Q92630	DYRK2	S739	T744M	744	Missense	distal	5	no	67.423	66.934	EPSD	COSMIC	45.963	Down-regulation
CMGC_DYRK_DYRK2_DYRK2_ST	P10636	MAPT	Q92630	DYRK2	S739	A743T	743	Missense	distal	4	no	67.423	67.597	EPSD	COSMIC	45.963	Up-regulation
CMGC_DYRK_DYRK2_DYRK2_ST	P43686	PSMC4	Q92630	DYRK2	T25	L27V	27	Missense	proximal	2	no	64.572	65.268	PhosphoSitePlus	COSMIC	45.963	Up-regulation
CMGC_DYRK_DYRK2_DYRK2_ST	Q9UHD2	TBK1	Q92630	DYRK2	T278	R271P	271	Missense	distal	-7	no	46.639	48.072	EPSD	COSMIC	45.963	Up-regulation
CMGC_DYRK_DYRK2_DYRK2_ST	Q9UHD2	TBK1	Q92630	DYRK2	T278	Q274H	274	Missense	distal	-4	no	46.639	39.951	EPSD	COSMIC	45.963	Loss
CMGC_DYRK_DYRK2_DYRK2_ST	Q9UHD2	TBK1	Q92630	DYRK2	S527	D534N	534	Missense	distal	7	no	80.649	81.193	PhosphoSitePlus	COSMIC	45.963	Up-regulation
CMGC_DYRK_DYRK2_DYRK2_ST	Q9UHD2	TBK1	Q92630	DYRK2	T674	G668E	668	Missense	distal	-6	no	59.959	60.027	EPSD	COSMIC	45.963	Up-regulation
CMGC_DYRK_DYRK2_DYRK2_ST	Q9UHD2	TBK1	Q92630	DYRK2	T674	P675L	675	Missense	proximal	1	no	59.959	11.745	EPSD	COSMIC	45.963	Loss
CMGC_DYRK_DYRK2_DYRK2_ST	Q9UHD2	TBK1	Q92630	DYRK2	T674	N681S	681	Missense	distal	7	no	59.959	57.782	EPSD	COSMIC	45.963	Down-regulation
CMGC_DYRK_DYRK2_DYRK2_ST	Q14194	CRMP1	Q92630	DYRK2	S304	A298V	298	Missense	distal	-6	no	57.122	56.884	EPSD	COSMIC	45.963	Down-regulation
CMGC_DYRK_DYRK2_DYRK2_ST	Q14194	CRMP1	Q92630	DYRK2	S304	A298T	298	Missense	distal	-6	no	57.122	56.938	EPSD	COSMIC	45.963	Down-regulation
CMGC_DYRK_DYRK2_DYRK2_ST	Q14194	CRMP1	Q92630	DYRK2	S304	A300T	300	Missense	distal	-4	no	57.122	54.412	EPSD	COSMIC;CCLE	45.963	Down-regulation
CMGC_DYRK_DYRK2_DYRK2_ST	Q14194	CRMP1	Q92630	DYRK2	S308	P314T	314	Missense	distal	6	no	48.268	48.234	EPSD	COSMIC;CCLE	45.963	Down-regulation
CMGC_DYRK_DYRK2_DYRK2_ST	Q14194	CRMP1	Q92630	DYRK2	T509	A508G	508	Missense	proximal	-1	no	59.847	60.483	EPSD	COSMIC	45.963	Up-regulation
CMGC_DYRK_DYRK2_DYRK2_ST	Q14194	CRMP1	Q92630	DYRK2	T509	P515L	515	Missense	distal	6	no	59.847	59.363	EPSD	COSMIC	45.963	Down-regulation
CMGC_DYRK_DYRK2_DYRK2_ST	Q14194	CRMP1	Q92630	DYRK2	T509	P510H	510	Missense	proximal	1	no	59.847	-49.382	EPSD	COSMIC	45.963	Loss
CMGC_DYRK_DYRK2_DYRK2_ST	Q14194	CRMP1	Q92630	DYRK2	T509	E505K	505	Missense	distal	-4	no	59.847	60.816	EPSD	COSMIC	45.963	Up-regulation
CMGC_DYRK_DYRK2_DYRK2_ST	Q14194	CRMP1	Q92630	DYRK2	T509	E505D	505	Missense	distal	-4	no	59.847	63.593	EPSD	COSMIC	45.963	Up-regulation
CMGC_DYRK_DYRK2_DYRK2_ST	Q14194	CRMP1	Q92630	DYRK2	T509	A516V	516	Missense	distal	7	no	59.847	62.723	EPSD	COSMIC	45.963	Up-regulation
CMGC_DYRK_DYRK2_DYRK2_ST	Q14194	CRMP1	Q92630	DYRK2	T514	A508G	508	Missense	distal	-6	no	47.527	47.521	EPSD	COSMIC	45.963	Down-regulation
CMGC_DYRK_DYRK2_DYRK2_ST	Q14194	CRMP1	Q92630	DYRK2	T514	S521Y	521	Missense	distal	7	no	47.527	45.594	EPSD	COSMIC	45.963	Loss
CMGC_DYRK_DYRK2_DYRK2_ST	Q14194	CRMP1	Q92630	DYRK2	T514	P515L	515	Missense	proximal	1	no	47.527	-0.687	EPSD	COSMIC	45.963	Loss
CMGC_DYRK_DYRK2_DYRK2_ST	Q14194	CRMP1	Q92630	DYRK2	T514	P510H	510	Missense	distal	-4	no	47.527	46.080	EPSD	COSMIC	45.963	Down-regulation
CMGC_DYRK_DYRK2_DYRK2_ST	Q14194	CRMP1	Q92630	DYRK2	T514	A516V	516	Missense	proximal	2	no	47.527	47.409	EPSD	COSMIC	45.963	Down-regulation
CMGC_DYRK_DYRK2_DYRK2_ST	Q14194	CRMP1	Q92630	DYRK2	S522	S522L	522	Missense	central	0	yes	82.280	0.000	PhosphoSitePlus	COSMIC	45.963	Loss
CMGC_DYRK_DYRK2_DYRK2_ST	Q14194	CRMP1	Q92630	DYRK2	S522	S521Y	521	Missense	proximal	-1	no	82.280	82.417	PhosphoSitePlus	COSMIC	45.963	Up-regulation
CMGC_DYRK_DYRK2_DYRK2_ST	Q14194	CRMP1	Q92630	DYRK2	S522	P515L	515	Missense	distal	-7	no	82.280	80.560	PhosphoSitePlus	COSMIC	45.963	Down-regulation
CMGC_DYRK_DYRK2_DYRK2_ST	Q14194	CRMP1	Q92630	DYRK2	S522	Q527H	527	Missense	distal	5	no	82.280	79.669	PhosphoSitePlus	COSMIC;CCLE	45.963	Down-regulation
CMGC_DYRK_DYRK2_DYRK2_ST	Q14194	CRMP1	Q92630	DYRK2	S522	P528T	528	Missense	distal	6	no	82.280	82.246	PhosphoSitePlus	COSMIC	45.963	Down-regulation
CMGC_DYRK_DYRK2_DYRK2_ST	Q14194	CRMP1	Q92630	DYRK2	S522	P528L	528	Missense	distal	6	no	82.280	81.796	PhosphoSitePlus	COSMIC	45.963	Down-regulation
CMGC_DYRK_DYRK2_DYRK2_ST	Q14194	CRMP1	Q92630	DYRK2	S522	A516V	516	Missense	distal	-6	no	82.280	82.042	PhosphoSitePlus	COSMIC	45.963	Down-regulation
CMGC_DYRK_DYRK2_DYRK2_ST	Q14194	CRMP1	Q92630	DYRK2	S542	F539L	539	Missense	distal	-3	no	41.450	50.628	EPSD	COSMIC	45.963	Gain
CMGC_DYRK_DYRK2_DYRK2_ST	Q14194	CRMP1	Q92630	DYRK2	S542	F539V	539	Missense	distal	-3	no	41.450	46.800	EPSD	COSMIC	45.963	Gain
CMGC_DYRK_DYRK2_DYRK2_ST	Q14194	CRMP1	Q92630	DYRK2	T554	V559L	559	Missense	distal	5	no	48.580	48.318	EPSD	COSMIC	45.963	Down-regulation
CMGC_DYRK_DYRK2_DYRK2_ST	Q14194	CRMP1	Q92630	DYRK2	T554	R553C	553	Missense	proximal	-1	no	48.580	47.587	EPSD	COSMIC	45.963	Down-regulation
CMGC_DYRK_DYRK2_DYRK2_ST	Q14194	CRMP1	Q92630	DYRK2	T554	H556R	556	Missense	proximal	2	no	48.580	49.493	EPSD	COSMIC	45.963	Up-regulation
CMGC_DYRK_DYRK2_DYRK2_ST	Q14194	CRMP1	Q92630	DYRK2	T554	R557H	557	Missense	distal	3	no	48.580	45.574	EPSD	COSMIC	45.963	Loss
CMGC_DYRK_DYRK2_DYRK2_ST	Q14194	CRMP1	Q92630	DYRK2	T554	G555S	555	Missense	proximal	1	no	48.580	40.363	EPSD	COSMIC;CCLE	45.963	Loss
CMGC_DYRK_DYRK2_DYRK2_ST	Q14194	CRMP1	Q92630	DYRK2	T554	G555V	555	Missense	proximal	1	no	48.580	61.733	EPSD	COSMIC	45.963	Up-regulation
CMGC_DYRK_DYRK2_DYRK2_ST	Q14194	CRMP1	Q92630	DYRK2	T554	V559M	559	Missense	distal	5	no	48.580	48.791	EPSD	COSMIC	45.963	Up-regulation
CMGC_DYRK_DYRK2_DYRK2_ST	Q14194	CRMP1	Q92630	DYRK2	T569	S566A	566	Missense	distal	-3	no	55.373	58.176	EPSD	COSMIC	45.963	Up-regulation
Other_BUB_BUB1_ST	Q12834	CDC20	O43683	BUB1	S104	S104N	104	Missense	central	0	yes	0.000	0.000	EPSD	COSMIC	0.000	Loss
Other_BUB_BUB1_ST	Q12834	CDC20	O43683	BUB1	T106	T106A	106	Missense	central	0	yes	0.000	0.000	EPSD	COSMIC;GDSC;CCLE	0.000	Loss
Other_BUB_BUB1_ST	Q12834	CDC20	O43683	BUB1	T304	T304I	304	Missense	central	0	yes	0.000	0.000	EPSD	COSMIC	0.000	Loss
Other_BUB_BUB1_ST	O43683	BUB1	O43683	BUB1	S198	S198F	198	Missense	central	0	yes	0.000	0.000	EPSD;PhosphoSitePlus	COSMIC	0.000	Loss
Other_BUB_BUB1_ST	O43683	BUB1	O43683	BUB1	S314	S314F	314	Missense	central	0	yes	0.000	0.000	EPSD	COSMIC	0.000	Loss
Other_BUB_BUB1_ST	O43683	BUB1	O43683	BUB1	S381	S381N	381	Missense	central	0	yes	0.000	0.000	EPSD	COSMIC	0.000	Loss
Other_BUB_BUB1_ST	O43683	BUB1	O43683	BUB1	T392	T392A	392	Missense	central	0	yes	0.000	0.000	EPSD	COSMIC	0.000	Loss
Other_BUB_BUB1_ST	O43683	BUB1	O43683	BUB1	T392	T392K	392	Missense	central	0	yes	0.000	0.000	EPSD	COSMIC	0.000	Loss
Other_BUB_BUB1_ST	O43683	BUB1	O43683	BUB1	S419	S419N	419	Missense	central	0	yes	0.000	0.000	EPSD;PhosphoSitePlus	COSMIC	0.000	Loss
Other_BUB_BUB1_ST	O43683	BUB1	O43683	BUB1	T441	T441A	441	Missense	central	0	yes	0.000	0.000	EPSD	COSMIC	0.000	Loss
Other_BUB_BUB1_ST	O43683	BUB1	O43683	BUB1	T441	T441P	441	Missense	central	0	yes	0.000	0.000	EPSD	COSMIC;GDSC;CCLE	0.000	Loss
Other_BUB_BUB1_ST	O43683	BUB1	O43683	BUB1	T461	T461A	461	Missense	central	0	yes	0.000	0.000	EPSD	COSMIC	0.000	Loss
AGC_PKC_PKCh_PRKCE_ST	Q16625	OCLN	Q02156	PRKCE	S302	V308M	308	Missense	distal	6	no	14.168	13.885	EPSD	COSMIC;GDSC	13.948	Loss
AGC_PKC_PKCh_PRKCE_ST	Q16625	OCLN	Q02156	PRKCE	S302	K299N	299	Missense	distal	-3	no	14.168	6.794	EPSD	COSMIC	13.948	Loss
AGC_PKC_PKCh_PRKCE_ST	Q16625	OCLN	Q02156	PRKCE	S302	W297C	297	Missense	distal	-5	no	14.168	14.121	EPSD	COSMIC	13.948	Down-regulation
AGC_PKC_PKCh_PRKCE_ST	Q16625	OCLN	Q02156	PRKCE	S302	V308A	308	Missense	distal	6	no	14.168	13.855	EPSD	COSMIC	13.948	Loss
AGC_PKC_PKCh_PRKCE_ST	Q16625	OCLN	Q02156	PRKCE	S302	W297L	297	Missense	distal	-5	no	14.168	14.112	EPSD	COSMIC;GDSC	13.948	Down-regulation
AGC_PKC_PKCh_PRKCE_ST	O14649	KCNK3	Q02156	PRKCE	T383	R385H	385	Missense	proximal	2	no	20.307	13.335	PhosphoSitePlus	COSMIC	13.948	Loss
AGC_PKC_PKCh_PRKCE_ST	O14649	KCNK3	Q02156	PRKCE	S392	R385H	385	Missense	distal	-7	no	22.025	21.560	EPSD	COSMIC	13.948	Down-regulation
AGC_PKC_PKCh_PRKCE_ST	P11362	FGFR1	Q02156	PRKCE	T403	S406N	406	Missense	distal	3	no	18.942	19.105	EPSD	COSMIC	13.948	Up-regulation
AGC_PKC_PKCh_PRKCE_ST	P11362	FGFR1	Q02156	PRKCE	T403	K398N	398	Missense	distal	-5	no	18.942	18.946	EPSD	COSMIC	13.948	Up-regulation
AGC_PKC_PKCh_PRKCE_ST	P11362	FGFR1	Q02156	PRKCE	T403	T403I	403	Missense	central	0	yes	18.942	0.000	EPSD	COSMIC	13.948	Loss
AGC_PKC_PKCh_PRKCE_ST	P11362	FGFR1	Q02156	PRKCE	S779	R784Q	784	Missense	distal	5	no	13.943	14.192	PhosphoSitePlus	COSMIC	13.948	Gain
AGC_PKC_PKCh_PRKCE_ST	P11362	FGFR1	Q02156	PRKCE	S779	R784W	784	Missense	distal	5	no	13.943	14.712	PhosphoSitePlus	COSMIC	13.948	Gain
AGC_PKC_PKCh_PRKCE_ST	P11362	FGFR1	Q02156	PRKCE	S779	P772S	772	Missense	distal	-7	no	13.943	14.069	PhosphoSitePlus	COSMIC;GDSC	13.948	Gain
AGC_PKC_PKCh_PRKCE_ST	P11362	FGFR1	Q02156	PRKCE	S797	H798Y	798	Missense	proximal	1	no	11.643	15.794	EPSD	COSMIC	13.948	Gain
AGC_PKC_PKCh_PRKCE_ST	P10636	MAPT	Q02156	PRKCE	S64	E62K	62	Missense	proximal	-2	no	13.304	15.229	EPSD	COSMIC	13.948	Gain
AGC_PKC_PKCh_PRKCE_ST	P10636	MAPT	Q02156	PRKCE	T167	P160Q	160	Missense	distal	-7	no	14.232	14.349	EPSD	COSMIC	13.948	Up-regulation
AGC_PKC_PKCh_PRKCE_ST	P10636	MAPT	Q02156	PRKCE	T167	A166V	166	Missense	proximal	-1	no	14.232	14.036	EPSD	COSMIC;CCLE	13.948	Down-regulation
AGC_PKC_PKCh_PRKCE_ST	P10636	MAPT	Q02156	PRKCE	T167	E165K	165	Missense	proximal	-2	no	14.232	16.158	EPSD	COSMIC	13.948	Up-regulation
AGC_PKC_PKCh_PRKCE_ST	P10636	MAPT	Q02156	PRKCE	T167	P160S	160	Missense	distal	-7	no	14.232	14.358	EPSD	COSMIC	13.948	Up-regulation
AGC_PKC_PKCh_PRKCE_ST	P10636	MAPT	Q02156	PRKCE	T167	G172V	172	Missense	distal	5	no	14.232	14.321	EPSD	COSMIC	13.948	Up-regulation
AGC_PKC_PKCh_PRKCE_ST	P10636	MAPT	Q02156	PRKCE	S214	E210Q	210	Missense	distal	-4	no	15.548	15.574	EPSD	COSMIC	13.948	Up-regulation
AGC_PKC_PKCh_PRKCE_ST	P10636	MAPT	Q02156	PRKCE	S214	G207E	207	Missense	distal	-7	no	15.548	15.649	EPSD	COSMIC	13.948	Up-regulation
AGC_PKC_PKCh_PRKCE_ST	P10636	MAPT	Q02156	PRKCE	S341	A337T	337	Missense	distal	-4	no	20.741	20.642	EPSD	COSMIC	13.948	Down-regulation
AGC_PKC_PKCh_PRKCE_ST	P10636	MAPT	Q02156	PRKCE	S341	G343R	343	Missense	proximal	2	no	20.741	25.653	EPSD	COSMIC	13.948	Up-regulation
AGC_PKC_PKCh_PRKCE_ST	P10636	MAPT	Q02156	PRKCE	S341	D345G	345	Missense	distal	4	no	20.741	22.153	EPSD	COSMIC	13.948	Up-regulation
AGC_PKC_PKCh_PRKCE_ST	P10636	MAPT	Q02156	PRKCE	S341	K347N	347	Missense	distal	6	no	20.741	20.695	EPSD	COSMIC	13.948	Down-regulation
AGC_PKC_PKCh_PRKCE_ST	P10636	MAPT	Q02156	PRKCE	S355	A361S	361	Missense	distal	6	no	15.706	15.897	EPSD	COSMIC;GDSC;CCLE	13.948	Up-regulation
AGC_PKC_PKCh_PRKCE_ST	P10636	MAPT	Q02156	PRKCE	S355	P354L	354	Missense	proximal	-1	no	15.706	15.771	EPSD	COSMIC	13.948	Up-regulation
AGC_PKC_PKCh_PRKCE_ST	P10636	MAPT	Q02156	PRKCE	S369	V368I	368	Missense	proximal	-1	no	15.708	15.464	EPSD	COSMIC	13.948	Down-regulation
AGC_PKC_PKCh_PRKCE_ST	P10636	MAPT	Q02156	PRKCE	S369	R370W	370	Missense	proximal	1	no	15.708	13.998	EPSD	COSMIC	13.948	Down-regulation
AGC_PKC_PKCh_PRKCE_ST	P10636	MAPT	Q02156	PRKCE	S396	R398C	398	Missense	proximal	2	no	20.731	14.308	EPSD	COSMIC	13.948	Down-regulation
AGC_PKC_PKCh_PRKCE_ST	P10636	MAPT	Q02156	PRKCE	S396	S396F	396	Missense	central	0	yes	20.731	0.000	EPSD	COSMIC	13.948	Loss
AGC_PKC_PKCh_PRKCE_ST	P10636	MAPT	Q02156	PRKCE	S396	D389N	389	Missense	distal	-7	no	20.731	20.632	EPSD	COSMIC;GDSC;CCLE	13.948	Down-regulation
AGC_PKC_PKCh_PRKCE_ST	P10636	MAPT	Q02156	PRKCE	S400	R398C	398	Missense	proximal	-2	no	18.204	16.701	EPSD	COSMIC	13.948	Down-regulation
AGC_PKC_PKCh_PRKCE_ST	P10636	MAPT	Q02156	PRKCE	S400	S396F	396	Missense	distal	-4	no	18.204	18.057	EPSD	COSMIC	13.948	Down-regulation
AGC_PKC_PKCh_PRKCE_ST	P10636	MAPT	Q02156	PRKCE	S438	S443Y	443	Missense	distal	5	no	14.553	14.570	EPSD	COSMIC	13.948	Up-regulation
AGC_PKC_PKCh_PRKCE_ST	P10636	MAPT	Q02156	PRKCE	S451	S447P	447	Missense	distal	-4	no	19.978	19.888	EPSD	COSMIC	13.948	Down-regulation
AGC_PKC_PKCh_PRKCE_ST	P10636	MAPT	Q02156	PRKCE	S451	R448Q	448	Missense	distal	-3	no	19.978	14.411	EPSD	COSMIC	13.948	Down-regulation
AGC_PKC_PKCh_PRKCE_ST	P10636	MAPT	Q02156	PRKCE	S554	P550S	550	Missense	distal	-4	no	15.711	15.801	EPSD	COSMIC	13.948	Up-regulation
AGC_PKC_PKCh_PRKCE_ST	P10636	MAPT	Q02156	PRKCE	S554	R559C	559	Missense	distal	5	no	15.711	16.001	EPSD	COSMIC	13.948	Up-regulation
AGC_PKC_PKCh_PRKCE_ST	P10636	MAPT	Q02156	PRKCE	S554	P553R	553	Missense	proximal	-1	no	15.711	16.519	EPSD	COSMIC	13.948	Up-regulation
AGC_PKC_PKCh_PRKCE_ST	P10636	MAPT	Q02156	PRKCE	S554	P553L	553	Missense	proximal	-1	no	15.711	15.776	EPSD	COSMIC	13.948	Up-regulation
AGC_PKC_PKCh_PRKCE_ST	P10636	MAPT	Q02156	PRKCE	S554	P549L	549	Missense	distal	-5	no	15.711	15.706	EPSD	COSMIC	13.948	Down-regulation
AGC_PKC_PKCh_PRKCE_ST	P10636	MAPT	Q02156	PRKCE	S554	S555F	555	Missense	proximal	1	no	15.711	17.047	EPSD	COSMIC	13.948	Up-regulation
AGC_PKC_PKCh_PRKCE_ST	P10636	MAPT	Q02156	PRKCE	S554	P553Q	553	Missense	proximal	-1	no	15.711	16.220	EPSD	COSMIC	13.948	Up-regulation
AGC_PKC_PKCh_PRKCE_ST	P10636	MAPT	Q02156	PRKCE	S555	P550S	550	Missense	distal	-5	no	15.616	15.635	EPSD	COSMIC	13.948	Up-regulation
AGC_PKC_PKCh_PRKCE_ST	P10636	MAPT	Q02156	PRKCE	S555	R559C	559	Missense	distal	4	no	15.616	12.954	EPSD	COSMIC	13.948	Loss
AGC_PKC_PKCh_PRKCE_ST	P10636	MAPT	Q02156	PRKCE	S555	P553R	553	Missense	proximal	-2	no	15.616	16.287	EPSD	COSMIC	13.948	Up-regulation
AGC_PKC_PKCh_PRKCE_ST	P10636	MAPT	Q02156	PRKCE	S555	P553L	553	Missense	proximal	-2	no	15.616	13.183	EPSD	COSMIC	13.948	Loss
AGC_PKC_PKCh_PRKCE_ST	P10636	MAPT	Q02156	PRKCE	S555	P549L	549	Missense	distal	-6	no	15.616	15.596	EPSD	COSMIC	13.948	Down-regulation
AGC_PKC_PKCh_PRKCE_ST	P10636	MAPT	Q02156	PRKCE	S555	S555F	555	Missense	central	0	yes	15.616	0.000	EPSD	COSMIC	13.948	Loss
AGC_PKC_PKCh_PRKCE_ST	P10636	MAPT	Q02156	PRKCE	S555	P553Q	553	Missense	proximal	-2	no	15.616	15.316	EPSD	COSMIC	13.948	Down-regulation
AGC_PKC_PKCh_PRKCE_ST	P10636	MAPT	Q02156	PRKCE	T562	V565M	565	Missense	distal	3	no	15.090	14.890	EPSD	COSMIC	13.948	Down-regulation
AGC_PKC_PKCh_PRKCE_ST	P10636	MAPT	Q02156	PRKCE	T562	P566S	566	Missense	distal	4	no	15.090	15.216	EPSD	COSMIC	13.948	Up-regulation
AGC_PKC_PKCh_PRKCE_ST	P10636	MAPT	Q02156	PRKCE	T562	R559C	559	Missense	distal	-3	no	15.090	7.000	EPSD	COSMIC	13.948	Loss
AGC_PKC_PKCh_PRKCE_ST	P10636	MAPT	Q02156	PRKCE	T562	S555F	555	Missense	distal	-7	no	15.090	14.812	EPSD	COSMIC	13.948	Down-regulation
AGC_PKC_PKCh_PRKCE_ST	P10636	MAPT	Q02156	PRKCE	T562	P568S	568	Missense	distal	6	no	15.090	14.985	EPSD	COSMIC	13.948	Down-regulation
AGC_PKC_PKCh_PRKCE_ST	P10636	MAPT	Q02156	PRKCE	S575	T580N	580	Missense	distal	5	no	15.947	15.732	EPSD	COSMIC	13.948	Down-regulation
AGC_PKC_PKCh_PRKCE_ST	P10636	MAPT	Q02156	PRKCE	S575	G578S	578	Missense	distal	3	no	15.947	15.665	EPSD	COSMIC	13.948	Down-regulation
AGC_PKC_PKCh_PRKCE_ST	P10636	MAPT	Q02156	PRKCE	S575	K571E	571	Missense	distal	-4	no	15.947	15.794	EPSD	COSMIC	13.948	Down-regulation
AGC_PKC_PKCh_PRKCE_ST	P10636	MAPT	Q02156	PRKCE	S575	P568S	568	Missense	distal	-7	no	15.947	16.073	EPSD	COSMIC	13.948	Up-regulation
AGC_PKC_PKCh_PRKCE_ST	P10636	MAPT	Q02156	PRKCE	S610	N613D	613	Missense	distal	3	no	14.001	14.089	EPSD	COSMIC	13.948	Up-regulation
AGC_PKC_PKCh_PRKCE_ST	P10636	MAPT	Q02156	PRKCE	S610	C608W	608	Missense	proximal	-2	no	14.001	12.286	EPSD	COSMIC	13.948	Loss
AGC_PKC_PKCh_PRKCE_ST	P10636	MAPT	Q02156	PRKCE	S610	S610L	610	Missense	central	0	yes	14.001	0.000	EPSD	COSMIC	13.948	Loss
AGC_PKC_PKCh_PRKCE_ST	P10636	MAPT	Q02156	PRKCE	S637	S633N	633	Missense	distal	-4	no	14.905	14.901	EPSD	COSMIC	13.948	Down-regulation
AGC_PKC_PKCh_PRKCE_ST	P10636	MAPT	Q02156	PRKCE	S637	S633I	633	Missense	distal	-4	no	14.905	14.953	EPSD	COSMIC	13.948	Up-regulation
AGC_PKC_PKCh_PRKCE_ST	P10636	MAPT	Q02156	PRKCE	S641	H647Y	647	Missense	distal	6	no	16.858	16.345	EPSD	COSMIC	13.948	Down-regulation
AGC_PKC_PKCh_PRKCE_ST	P10636	MAPT	Q02156	PRKCE	S658	D662G	662	Missense	distal	4	no	19.950	21.362	EPSD	COSMIC	13.948	Up-regulation
AGC_PKC_PKCh_PRKCE_ST	P10636	MAPT	Q02156	PRKCE	S658	K664N	664	Missense	distal	6	no	19.950	19.904	EPSD	COSMIC	13.948	Down-regulation
AGC_PKC_PKCh_PRKCE_ST	P10636	MAPT	Q02156	PRKCE	S669	S669L	669	Missense	central	0	yes	17.810	0.000	EPSD	COSMIC	13.948	Loss
AGC_PKC_PKCh_PRKCE_ST	P10636	MAPT	Q02156	PRKCE	S669	R666K	666	Missense	distal	-3	no	17.810	17.828	EPSD	COSMIC	13.948	Up-regulation
AGC_PKC_PKCh_PRKCE_ST	P10636	MAPT	Q02156	PRKCE	S669	D662G	662	Missense	distal	-7	no	17.810	17.739	EPSD	COSMIC	13.948	Down-regulation
AGC_PKC_PKCh_PRKCE_ST	P10636	MAPT	Q02156	PRKCE	S669	S673F	673	Missense	distal	4	no	17.810	18.193	EPSD	COSMIC	13.948	Up-regulation
AGC_PKC_PKCh_PRKCE_ST	P10636	MAPT	Q02156	PRKCE	S669	K670N	670	Missense	proximal	1	no	17.810	15.191	EPSD	COSMIC	13.948	Down-regulation
AGC_PKC_PKCh_PRKCE_ST	P10636	MAPT	Q02156	PRKCE	S669	K664N	664	Missense	distal	-5	no	17.810	17.814	EPSD	COSMIC	13.948	Up-regulation
AGC_PKC_PKCh_PRKCE_ST	P10636	MAPT	Q02156	PRKCE	S669	L674Q	674	Missense	distal	5	no	17.810	17.874	EPSD	COSMIC	13.948	Up-regulation
AGC_PKC_PKCh_PRKCE_ST	P10636	MAPT	Q02156	PRKCE	S673	V680I	680	Missense	distal	7	no	15.361	15.855	EPSD	COSMIC	13.948	Up-regulation
AGC_PKC_PKCh_PRKCE_ST	P10636	MAPT	Q02156	PRKCE	S673	S669L	669	Missense	distal	-4	no	15.361	15.275	EPSD	COSMIC	13.948	Down-regulation
AGC_PKC_PKCh_PRKCE_ST	P10636	MAPT	Q02156	PRKCE	S673	R666K	666	Missense	distal	-7	no	15.361	15.141	EPSD	COSMIC	13.948	Down-regulation
AGC_PKC_PKCh_PRKCE_ST	P10636	MAPT	Q02156	PRKCE	S673	S673F	673	Missense	central	0	yes	15.361	0.000	EPSD	COSMIC	13.948	Loss
AGC_PKC_PKCh_PRKCE_ST	P10636	MAPT	Q02156	PRKCE	S673	K670N	670	Missense	distal	-3	no	15.361	7.987	EPSD	COSMIC	13.948	Loss
AGC_PKC_PKCh_PRKCE_ST	P10636	MAPT	Q02156	PRKCE	S673	L674Q	674	Missense	proximal	1	no	15.361	14.310	EPSD	COSMIC	13.948	Down-regulation
AGC_PKC_PKCh_PRKCE_ST	P10636	MAPT	Q02156	PRKCE	S726	G732S	732	Missense	distal	6	no	15.001	15.080	EPSD	COSMIC	13.948	Up-regulation
AGC_PKC_PKCh_PRKCE_ST	P10636	MAPT	Q02156	PRKCE	S726	G732C	732	Missense	distal	6	no	15.001	15.044	EPSD	COSMIC	13.948	Up-regulation
AGC_PKC_PKCh_PRKCE_ST	P10636	MAPT	Q02156	PRKCE	S726	R723W	723	Missense	distal	-3	no	15.001	4.004	EPSD	COSMIC	13.948	Loss
AGC_PKC_PKCh_PRKCE_ST	P10636	MAPT	Q02156	PRKCE	S726	V728M	728	Missense	proximal	2	no	15.001	6.203	EPSD	COSMIC	13.948	Loss
AGC_PKC_PKCh_PRKCE_ST	P10636	MAPT	Q02156	PRKCE	S726	V728A	728	Missense	proximal	2	no	15.001	12.583	EPSD	COSMIC	13.948	Loss
AGC_PKC_PKCh_PRKCE_ST	P10636	MAPT	Q02156	PRKCE	S733	G732S	732	Missense	proximal	-1	no	15.481	15.277	EPSD	COSMIC	13.948	Down-regulation
AGC_PKC_PKCh_PRKCE_ST	P10636	MAPT	Q02156	PRKCE	S733	D735N	735	Missense	proximal	2	no	15.481	15.077	EPSD	COSMIC	13.948	Down-regulation
AGC_PKC_PKCh_PRKCE_ST	P10636	MAPT	Q02156	PRKCE	S733	G732C	732	Missense	proximal	-1	no	15.481	15.290	EPSD	COSMIC	13.948	Down-regulation
AGC_PKC_PKCh_PRKCE_ST	P10636	MAPT	Q02156	PRKCE	S733	V728M	728	Missense	distal	-5	no	15.481	15.510	EPSD	COSMIC	13.948	Up-regulation
AGC_PKC_PKCh_PRKCE_ST	P10636	MAPT	Q02156	PRKCE	S733	V728A	728	Missense	distal	-5	no	15.481	15.508	EPSD	COSMIC	13.948	Up-regulation
AGC_PKC_PKCh_PRKCE_ST	P10636	MAPT	Q02156	PRKCE	S750	E748K	748	Missense	proximal	-2	no	12.325	14.250	EPSD	COSMIC	13.948	Gain
AGC_PKC_PKCh_PRKCE_ST	P10636	MAPT	Q02156	PRKCE	S752	E748K	748	Missense	distal	-4	no	14.787	14.940	EPSD	COSMIC	13.948	Up-regulation
AGC_PKC_PKCh_PRKCE_ST	O75689	ADAP1	Q02156	PRKCE	S87	A81E	81	Missense	distal	-6	no	16.708	16.731	EPSD;PhosphoSitePlus	COSMIC;CCLE	13.948	Up-regulation
AGC_PKC_PKCh_PRKCE_ST	O75689	ADAP1	Q02156	PRKCE	S87	Y94H	94	Missense	distal	7	no	16.708	15.518	EPSD;PhosphoSitePlus	COSMIC	13.948	Down-regulation
AGC_PKC_PKCh_PRKCE_ST	O75689	ADAP1	Q02156	PRKCE	S204	R206C	206	Missense	proximal	2	no	18.789	12.365	EPSD	COSMIC	13.948	Loss
AGC_PKC_PKCh_PRKCE_ST	O75689	ADAP1	Q02156	PRKCE	S204	S204N	204	Missense	central	0	yes	18.789	0.000	EPSD	COSMIC	13.948	Loss
AGC_PKC_PKCh_PRKCE_ST	O75689	ADAP1	Q02156	PRKCE	S204	R206S	206	Missense	proximal	2	no	18.789	12.351	EPSD	COSMIC	13.948	Loss
AGC_PKC_PKCh_PRKCE_ST	O75689	ADAP1	Q02156	PRKCE	S204	V197A	197	Missense	distal	-7	no	18.789	18.939	EPSD	COSMIC	13.948	Up-regulation
AGC_PKC_PKCh_PRKCE_ST	O75689	ADAP1	Q02156	PRKCE	S204	L200P	200	Missense	distal	-4	no	18.789	18.785	EPSD	COSMIC	13.948	Down-regulation
AGC_PKC_PKCh_PRKCE_ST	O75689	ADAP1	Q02156	PRKCE	T276	K272N	272	Missense	distal	-4	no	15.841	15.881	PhosphoSitePlus;EPSD	COSMIC	13.948	Up-regulation
AGC_PKC_PKCh_PRKCE_ST	O75689	ADAP1	Q02156	PRKCE	T276	D279Y	279	Missense	distal	3	no	15.841	15.602	PhosphoSitePlus;EPSD	COSMIC	13.948	Down-regulation
AGC_PKC_PKCh_PRKCE_ST	Q86XR7	TICAM2	Q02156	PRKCE	S16	S14F	14	Missense	proximal	-2	no	14.368	12.503	PhosphoSitePlus	COSMIC	13.948	Loss
AGC_PKC_PKCh_PRKCE_ST	Q9H9S0	NANOG	Q02156	PRKCE	S71	S69P	69	Missense	proximal	-2	no	16.922	17.062	EPSD	COSMIC	13.948	Up-regulation
AGC_PKC_PKCh_PRKCE_ST	Q9H9S0	NANOG	Q02156	PRKCE	S71	S65N	65	Missense	distal	-6	no	16.922	16.876	EPSD	COSMIC	13.948	Down-regulation
AGC_PKC_PKCh_PRKCE_ST	Q9H9S0	NANOG	Q02156	PRKCE	T200	N202S	202	Missense	proximal	2	no	15.548	14.884	EPSD;PhosphoSitePlus	COSMIC	13.948	Down-regulation
AGC_PKC_PKCh_PRKCE_ST	Q14145	KEAP1	Q02156	PRKCE	S599	S592R	592	Missense	distal	-7	no	31.933	32.104	EPSD;PhosphoSitePlus	COSMIC	13.948	Up-regulation
AGC_PKC_PKCh_PRKCE_ST	Q14145	KEAP1	Q02156	PRKCE	S599	V606M	606	Missense	distal	7	no	31.933	32.998	EPSD;PhosphoSitePlus	COSMIC	13.948	Up-regulation
AGC_PKC_PKCh_PRKCE_ST	Q14145	KEAP1	Q02156	PRKCE	S599	E593K	593	Missense	distal	-6	no	31.933	32.009	EPSD;PhosphoSitePlus	COSMIC	13.948	Up-regulation
AGC_PKC_PKCh_PRKCE_ST	Q14145	KEAP1	Q02156	PRKCE	S599	R601W	601	Missense	proximal	2	no	31.933	19.259	EPSD;PhosphoSitePlus	COSMIC	13.948	Down-regulation
AGC_PKC_PKCh_PRKCE_ST	Q14145	KEAP1	Q02156	PRKCE	S599	R596Q	596	Missense	distal	-3	no	31.933	26.366	EPSD;PhosphoSitePlus	COSMIC	13.948	Down-regulation
AGC_PKC_PKCh_PRKCE_ST	Q14145	KEAP1	Q02156	PRKCE	S599	G603V	603	Missense	distal	4	no	31.933	31.414	EPSD;PhosphoSitePlus	COSMIC;CCLE	13.948	Down-regulation
AGC_PKC_PKCh_PRKCE_ST	Q14145	KEAP1	Q02156	PRKCE	S599	G605R	605	Missense	distal	6	no	31.933	31.590	EPSD;PhosphoSitePlus	COSMIC	13.948	Down-regulation
AGC_PKC_PKCh_PRKCE_ST	Q14145	KEAP1	Q02156	PRKCE	S602	V606M	606	Missense	distal	4	no	19.003	17.377	PhosphoSitePlus;EPSD	COSMIC	13.948	Down-regulation
AGC_PKC_PKCh_PRKCE_ST	Q14145	KEAP1	Q02156	PRKCE	S602	R601W	601	Missense	proximal	-1	no	19.003	17.650	PhosphoSitePlus;EPSD	COSMIC	13.948	Down-regulation
AGC_PKC_PKCh_PRKCE_ST	Q14145	KEAP1	Q02156	PRKCE	S602	R596Q	596	Missense	distal	-6	no	19.003	18.898	PhosphoSitePlus;EPSD	COSMIC	13.948	Down-regulation
AGC_PKC_PKCh_PRKCE_ST	Q14145	KEAP1	Q02156	PRKCE	S602	G603V	603	Missense	proximal	1	no	19.003	18.106	PhosphoSitePlus;EPSD	COSMIC;CCLE	13.948	Down-regulation
AGC_PKC_PKCh_PRKCE_ST	Q14145	KEAP1	Q02156	PRKCE	S602	G605R	605	Missense	distal	3	no	19.003	18.968	PhosphoSitePlus;EPSD	COSMIC	13.948	Down-regulation
AGC_PKC_PKCh_PRKCE_ST	Q14145	KEAP1	Q02156	PRKCE	T609	E611K	611	Missense	proximal	2	no	9.681	16.348	EPSD	COSMIC	13.948	Gain
AGC_PKC_PKCh_PRKCE_ST	Q92934	BAD	Q02156	PRKCE	S75	A78E	78	Missense	distal	3	no	18.907	18.796	PhosphoSitePlus;EPSD	COSMIC	13.948	Down-regulation
AGC_PKC_PKCh_PRKCE_ST	Q92934	BAD	Q02156	PRKCE	S97	P102L	102	Missense	distal	5	no	17.410	17.287	EPSD	COSMIC	13.948	Down-regulation
AGC_PKC_PKCh_PRKCE_ST	Q92934	BAD	Q02156	PRKCE	S97	S97P	97	Missense	central	0	yes	17.410	0.000	EPSD	COSMIC	13.948	Loss
AGC_PKC_PKCh_PRKCE_ST	Q92934	BAD	Q02156	PRKCE	S97	R98H	98	Missense	proximal	1	no	17.410	14.858	EPSD	COSMIC	13.948	Down-regulation
AGC_PKC_PKCh_PRKCE_ST	Q92934	BAD	Q02156	PRKCE	S97	P101S	101	Missense	distal	4	no	17.410	17.536	EPSD	COSMIC	13.948	Up-regulation
AGC_PKC_PKCh_PRKCE_ST	Q92934	BAD	Q02156	PRKCE	S99	P102L	102	Missense	distal	3	no	15.361	15.163	EPSD;PhosphoSitePlus	COSMIC	13.948	Down-regulation
AGC_PKC_PKCh_PRKCE_ST	Q92934	BAD	Q02156	PRKCE	S99	S97P	97	Missense	proximal	-2	no	15.361	15.501	EPSD;PhosphoSitePlus	COSMIC	13.948	Up-regulation
AGC_PKC_PKCh_PRKCE_ST	Q92934	BAD	Q02156	PRKCE	S99	R98H	98	Missense	proximal	-1	no	15.361	14.024	EPSD;PhosphoSitePlus	COSMIC	13.948	Down-regulation
AGC_PKC_PKCh_PRKCE_ST	Q92934	BAD	Q02156	PRKCE	S99	P101S	101	Missense	proximal	2	no	15.361	14.707	EPSD;PhosphoSitePlus	COSMIC	13.948	Down-regulation
AGC_PKC_PKCh_PRKCE_ST	Q92934	BAD	Q02156	PRKCE	S118	S124F	124	Missense	distal	6	no	16.614	16.647	EPSD;PhosphoSitePlus	COSMIC	13.948	Up-regulation
AGC_PKC_PKCh_PRKCE_ST	Q92934	BAD	Q02156	PRKCE	S124	S124F	124	Missense	central	0	yes	21.399	0.000	EPSD	COSMIC	13.948	Loss
AGC_PKC_PKCh_PRKCE_ST	Q92934	BAD	Q02156	PRKCE	S124	K127N	127	Missense	distal	3	no	21.399	21.106	EPSD	COSMIC	13.948	Down-regulation
AGC_PKC_PKCh_PRKCE_ST	Q92934	BAD	Q02156	PRKCE	S145	W147R	147	Missense	proximal	2	no	6.570	19.243	EPSD	COSMIC	13.948	Gain
AGC_PKC_PKCh_PRKCE_ST	Q92934	BAD	Q02156	PRKCE	S163	R161S	161	Missense	proximal	-2	no	17.205	16.394	EPSD	COSMIC;GDSC	13.948	Down-regulation
AGC_PKC_PKCh_PRKCE_ST	Q92934	BAD	Q02156	PRKCE	S163	P166S	166	Missense	distal	3	no	17.205	17.145	EPSD	COSMIC	13.948	Down-regulation
AGC_PKC_PKCh_PRKCE_ST	Q92934	BAD	Q02156	PRKCE	S163	R161G	161	Missense	proximal	-2	no	17.205	16.615	EPSD	COSMIC	13.948	Down-regulation
AGC_PKC_PKCh_PRKCE_ST	Q92934	BAD	Q02156	PRKCE	S164	R161S	161	Missense	distal	-3	no	24.444	19.675	EPSD	COSMIC;GDSC	13.948	Down-regulation
AGC_PKC_PKCh_PRKCE_ST	Q92934	BAD	Q02156	PRKCE	S164	P166S	166	Missense	proximal	2	no	24.444	23.790	EPSD	COSMIC	13.948	Down-regulation
AGC_PKC_PKCh_PRKCE_ST	Q92934	BAD	Q02156	PRKCE	S164	R161G	161	Missense	distal	-3	no	24.444	17.185	EPSD	COSMIC	13.948	Down-regulation
AGC_PKC_PKCh_PRKCE_ST	P78536	ADAM17	Q02156	PRKCE	T761	R758I	758	Missense	distal	-3	no	14.126	9.929	EPSD	COSMIC	13.948	Loss
AGC_PKC_PKCh_PRKCE_ST	P78536	ADAM17	Q02156	PRKCE	T761	H756Q	756	Missense	distal	-5	no	14.126	14.101	EPSD	COSMIC	13.948	Down-regulation
AGC_PKC_PKCh_PRKCE_ST	P78536	ADAM17	Q02156	PRKCE	T761	D765N	765	Missense	distal	4	no	14.126	13.519	EPSD	COSMIC	13.948	Loss
AGC_PKC_PKCh_PRKCE_ST	P78536	ADAM17	Q02156	PRKCE	S819	E823A	823	Missense	distal	4	no	20.230	20.095	EPSD	COSMIC	13.948	Down-regulation
AGC_PKC_PKCh_PRKCE_ST	P04899	GNAI2	Q02156	PRKCE	S44	S47Y	47	Missense	distal	3	no	21.352	21.365	EPSD;PhosphoSitePlus	COSMIC	13.948	Up-regulation
AGC_PKC_PKCh_PRKCE_ST	P04899	GNAI2	Q02156	PRKCE	S44	T48S	48	Missense	distal	4	no	21.352	22.176	EPSD;PhosphoSitePlus	COSMIC	13.948	Up-regulation
AGC_PKC_PKCh_PRKCE_ST	P04899	GNAI2	Q02156	PRKCE	S44	G45W	45	Missense	proximal	1	no	21.352	19.443	EPSD;PhosphoSitePlus	COSMIC	13.948	Down-regulation
AGC_PKC_PKCh_PRKCE_ST	P04899	GNAI2	Q02156	PRKCE	S44	S47N	47	Missense	distal	3	no	21.352	21.515	EPSD;PhosphoSitePlus	COSMIC;GDSC;CCLE	13.948	Up-regulation
AGC_PKC_PKCh_PRKCE_ST	P04899	GNAI2	Q02156	PRKCE	S44	G45E	45	Missense	proximal	1	no	21.352	19.457	EPSD;PhosphoSitePlus	COSMIC	13.948	Down-regulation
AGC_PKC_PKCh_PRKCE_ST	P04899	GNAI2	Q02156	PRKCE	S44	K46E	46	Missense	proximal	2	no	21.352	14.686	EPSD;PhosphoSitePlus	COSMIC	13.948	Down-regulation
AGC_PKC_PKCh_PRKCE_ST	P04899	GNAI2	Q02156	PRKCE	S44	L39W	39	Missense	distal	-5	no	21.352	21.408	EPSD;PhosphoSitePlus	COSMIC	13.948	Up-regulation
AGC_PKC_PKCh_PRKCE_ST	P04899	GNAI2	Q02156	PRKCE	S44	L39F	39	Missense	distal	-5	no	21.352	21.346	EPSD;PhosphoSitePlus	COSMIC	13.948	Down-regulation
AGC_PKC_PKCh_PRKCE_ST	P04899	GNAI2	Q02156	PRKCE	S144	R143H	143	Missense	proximal	-1	no	16.773	15.435	PhosphoSitePlus;EPSD	COSMIC	13.948	Down-regulation
AGC_PKC_PKCh_PRKCE_ST	P04899	GNAI2	Q02156	PRKCE	S302	A301P	301	Missense	proximal	-1	no	16.150	15.915	EPSD;PhosphoSitePlus	COSMIC	13.948	Down-regulation
AGC_PKC_PKCh_PRKCE_ST	P16220	CREB1	Q02156	PRKCE	S121	V118I	118	Missense	distal	-3	no	12.415	14.528	EPSD	COSMIC	13.948	Gain
AGC_PKC_PKCh_PRKCE_ST	P16220	CREB1	Q02156	PRKCE	S129	R125T	125	Missense	distal	-4	no	13.881	14.076	EPSD	COSMIC	13.948	Gain
AGC_PKC_PKCh_PRKCE_ST	P16220	CREB1	Q02156	PRKCE	S129	L128R	128	Missense	proximal	-1	no	13.881	14.624	EPSD	COSMIC	13.948	Gain
AGC_PKC_PKCh_PRKCE_ST	P16220	CREB1	Q02156	PRKCE	S133	L128R	128	Missense	distal	-5	no	22.554	22.541	PhosphoSitePlus	COSMIC	13.948	Down-regulation
AGC_PKC_PKCh_PRKCE_ST	P43629	KIR3DL1	Q02156	PRKCE	T118	H121R	121	Missense	distal	3	no	15.832	16.746	EPSD	COSMIC	13.948	Up-regulation
AGC_PKC_PKCh_PRKCE_ST	P43629	KIR3DL1	Q02156	PRKCE	S225	E222K	222	Missense	distal	-3	no	8.292	15.419	EPSD	COSMIC	13.948	Gain
AGC_PKC_PKCh_PRKCE_ST	P43629	KIR3DL1	Q02156	PRKCE	S415	R413P	413	Missense	proximal	-2	no	17.613	16.942	PhosphoSitePlus	COSMIC	13.948	Down-regulation
AGC_PKC_PKCh_PRKCE_ST	P43629	KIR3DL1	Q02156	PRKCE	S415	R409T	409	Missense	distal	-6	no	17.613	17.399	PhosphoSitePlus	COSMIC	13.948	Down-regulation
AGC_PKC_PKCh_PRKCE_ST	P43629	KIR3DL1	Q02156	PRKCE	S415	K419E	419	Missense	distal	4	no	17.613	16.034	PhosphoSitePlus	COSMIC	13.948	Down-regulation
AGC_PKC_PKCh_PRKCE_ST	P43629	KIR3DL1	Q02156	PRKCE	S415	I411S	411	Missense	distal	-4	no	17.613	17.565	PhosphoSitePlus	COSMIC	13.948	Down-regulation
AGC_PKC_PKCh_PRKCE_ST	P43629	KIR3DL1	Q02156	PRKCE	T420	L427M	427	Missense	distal	7	no	14.228	15.148	EPSD	COSMIC	13.948	Up-regulation
AGC_PKC_PKCh_PRKCE_ST	P43629	KIR3DL1	Q02156	PRKCE	T420	R413P	413	Missense	distal	-7	no	14.228	13.930	EPSD	COSMIC	13.948	Loss
AGC_PKC_PKCh_PRKCE_ST	P43629	KIR3DL1	Q02156	PRKCE	T420	I426T	426	Missense	distal	6	no	14.228	14.216	EPSD	COSMIC	13.948	Down-regulation
AGC_PKC_PKCh_PRKCE_ST	P43629	KIR3DL1	Q02156	PRKCE	T420	L427V	427	Missense	distal	7	no	14.228	14.082	EPSD	COSMIC	13.948	Down-regulation
AGC_PKC_PKCh_PRKCE_ST	P43629	KIR3DL1	Q02156	PRKCE	T420	K419E	419	Missense	proximal	-1	no	14.228	14.331	EPSD	COSMIC	13.948	Up-regulation
AGC_PKC_PKCh_PRKCE_ST	P43629	KIR3DL1	Q02156	PRKCE	T420	I426V	426	Missense	distal	6	no	14.228	14.282	EPSD	COSMIC	13.948	Up-regulation
AGC_PKC_PKCh_PRKCE_ST	P43629	KIR3DL1	Q02156	PRKCE	S442	V440I	440	Missense	proximal	-2	no	15.499	14.610	EPSD	COSMIC	13.948	Down-regulation
AGC_PKC_PKCh_PRKCE_ST	Q9UBS0	RPS6KB2	Q02156	PRKCE	S15	E16K	16	Missense	proximal	1	no	11.812	14.499	EPSD	COSMIC	13.948	Gain
AGC_PKC_PKCh_PRKCE_ST	Q9UBS0	RPS6KB2	Q02156	PRKCE	S410	R413C	413	Missense	distal	3	no	17.760	17.352	EPSD	COSMIC	13.948	Down-regulation
AGC_PKC_PKCh_PRKCE_ST	Q9UBS0	RPS6KB2	Q02156	PRKCE	S410	R413H	413	Missense	distal	3	no	17.760	16.846	EPSD	COSMIC	13.948	Down-regulation
AGC_PKC_PKCh_PRKCE_ST	Q9UBS0	RPS6KB2	Q02156	PRKCE	S416	P421S	421	Missense	distal	5	no	15.168	15.060	EPSD	COSMIC	13.948	Down-regulation
AGC_PKC_PKCh_PRKCE_ST	Q9UBS0	RPS6KB2	Q02156	PRKCE	S416	R413C	413	Missense	distal	-3	no	15.168	7.078	EPSD	COSMIC	13.948	Loss
AGC_PKC_PKCh_PRKCE_ST	Q9UBS0	RPS6KB2	Q02156	PRKCE	S416	R413H	413	Missense	distal	-3	no	15.168	9.949	EPSD	COSMIC	13.948	Loss
AGC_PKC_PKCh_PRKCE_ST	Q9UBS0	RPS6KB2	Q02156	PRKCE	S416	P421L	421	Missense	distal	5	no	15.168	15.045	EPSD	COSMIC	13.948	Down-regulation
AGC_PKC_PKCh_PRKCE_ST	Q9UBS0	RPS6KB2	Q02156	PRKCE	S468	S468P	468	Missense	central	0	yes	18.613	0.000	EPSD	COSMIC	13.948	Loss
AGC_PKC_PKCh_PRKCE_ST	Q9UBS0	RPS6KB2	Q02156	PRKCE	S468	P463S	463	Missense	distal	-5	no	18.613	18.633	EPSD	COSMIC	13.948	Up-regulation
AGC_PKC_PKCh_PRKCE_ST	Q9UBS0	RPS6KB2	Q02156	PRKCE	S468	R475G	475	Missense	distal	7	no	18.613	17.931	EPSD	COSMIC	13.948	Down-regulation
AGC_PKC_PKCh_PRKCE_ST	Q9UBS0	RPS6KB2	Q02156	PRKCE	S468	P467H	467	Missense	proximal	-1	no	18.613	18.084	EPSD	COSMIC	13.948	Down-regulation
AGC_PKC_PKCh_PRKCE_ST	Q9UBS0	RPS6KB2	Q02156	PRKCE	S468	R465H	465	Missense	distal	-3	no	18.613	13.394	EPSD	COSMIC	13.948	Loss
AGC_PKC_PKCh_PRKCE_ST	Q9UBS0	RPS6KB2	Q02156	PRKCE	T470	S468P	468	Missense	proximal	-2	no	20.520	20.659	EPSD	COSMIC	13.948	Up-regulation
AGC_PKC_PKCh_PRKCE_ST	Q9UBS0	RPS6KB2	Q02156	PRKCE	T470	P463S	463	Missense	distal	-7	no	20.520	20.646	EPSD	COSMIC	13.948	Up-regulation
AGC_PKC_PKCh_PRKCE_ST	Q9UBS0	RPS6KB2	Q02156	PRKCE	T470	R477H	477	Missense	distal	7	no	20.520	19.690	EPSD	COSMIC	13.948	Down-regulation
AGC_PKC_PKCh_PRKCE_ST	Q9UBS0	RPS6KB2	Q02156	PRKCE	T470	R475G	475	Missense	distal	5	no	20.520	20.668	EPSD	COSMIC	13.948	Up-regulation
AGC_PKC_PKCh_PRKCE_ST	Q9UBS0	RPS6KB2	Q02156	PRKCE	T470	P467H	467	Missense	distal	-3	no	20.520	23.387	EPSD	COSMIC	13.948	Up-regulation
AGC_PKC_PKCh_PRKCE_ST	Q9UBS0	RPS6KB2	Q02156	PRKCE	T470	R465H	465	Missense	distal	-5	no	20.520	20.556	EPSD	COSMIC	13.948	Up-regulation
AGC_PKC_PKCh_PRKCE_ST	Q9UBS0	RPS6KB2	Q02156	PRKCE	S473	R479H	479	Missense	distal	6	no	25.194	25.882	PhosphoSitePlus	COSMIC;CCLE	13.948	Up-regulation
AGC_PKC_PKCh_PRKCE_ST	Q9UBS0	RPS6KB2	Q02156	PRKCE	S473	S468P	468	Missense	distal	-5	no	25.194	25.175	PhosphoSitePlus	COSMIC	13.948	Down-regulation
AGC_PKC_PKCh_PRKCE_ST	Q9UBS0	RPS6KB2	Q02156	PRKCE	S473	P480Q	480	Missense	distal	7	no	25.194	26.088	PhosphoSitePlus	COSMIC	13.948	Up-regulation
AGC_PKC_PKCh_PRKCE_ST	Q9UBS0	RPS6KB2	Q02156	PRKCE	S473	R477H	477	Missense	distal	4	no	25.194	22.375	PhosphoSitePlus	COSMIC	13.948	Down-regulation
AGC_PKC_PKCh_PRKCE_ST	Q9UBS0	RPS6KB2	Q02156	PRKCE	S473	R475G	475	Missense	proximal	2	no	25.194	20.282	PhosphoSitePlus	COSMIC	13.948	Down-regulation
AGC_PKC_PKCh_PRKCE_ST	Q9UBS0	RPS6KB2	Q02156	PRKCE	S473	P467H	467	Missense	distal	-6	no	25.194	25.145	PhosphoSitePlus	COSMIC	13.948	Down-regulation
AGC_PKC_PKCh_PRKCE_ST	P05783	KRT18	Q02156	PRKCE	S53	G59R	59	Missense	distal	6	no	23.709	23.366	PhosphoSitePlus	COSMIC	13.948	Down-regulation
AGC_PKC_PKCh_PRKCE_ST	P05783	KRT18	Q02156	PRKCE	S53	G59E	59	Missense	distal	6	no	23.709	23.494	PhosphoSitePlus	COSMIC	13.948	Down-regulation
AGC_PKC_PKCh_PRKCE_ST	P05783	KRT18	Q02156	PRKCE	S93	S100R	100	Missense	distal	7	no	13.707	14.057	EPSD	COSMIC	13.948	Gain
AGC_PKC_PKCh_PRKCE_ST	P05783	KRT18	Q02156	PRKCE	S100	S100R	100	Missense	central	0	yes	16.090	0.000	EPSD	COSMIC	13.948	Loss
AGC_PKC_PKCh_PRKCE_ST	Q02156	PRKCE	Q02156	PRKCE	T228	V232G	232	Missense	distal	4	no	13.654	14.172	EPSD	COSMIC	13.948	Gain
AGC_PKC_PKCh_PRKCE_ST	Q02156	PRKCE	Q02156	PRKCE	S234	V232G	232	Missense	proximal	-2	no	18.167	19.140	EPSD;PhosphoSitePlus	COSMIC	13.948	Up-regulation
AGC_PKC_PKCh_PRKCE_ST	Q02156	PRKCE	Q02156	PRKCE	S234	Q231H	231	Missense	distal	-3	no	18.167	18.514	EPSD;PhosphoSitePlus	COSMIC	13.948	Up-regulation
AGC_PKC_PKCh_PRKCE_ST	Q02156	PRKCE	Q02156	PRKCE	S234	R236Q	236	Missense	proximal	2	no	18.167	12.935	EPSD;PhosphoSitePlus	COSMIC	13.948	Loss
AGC_PKC_PKCh_PRKCE_ST	Q02156	PRKCE	Q02156	PRKCE	S234	G233C	233	Missense	proximal	-1	no	18.167	17.975	EPSD;PhosphoSitePlus	COSMIC	13.948	Down-regulation
AGC_PKC_PKCh_PRKCE_ST	Q02156	PRKCE	Q02156	PRKCE	S316	N315D	315	Missense	proximal	-1	no	14.918	14.834	PhosphoSitePlus;EPSD	COSMIC	13.948	Down-regulation
AGC_PKC_PKCh_PRKCE_ST	Q02156	PRKCE	Q02156	PRKCE	S368	N361T	361	Missense	distal	-7	no	18.283	18.120	EPSD;PhosphoSitePlus	COSMIC	13.948	Down-regulation
AGC_PKC_PKCh_PRKCE_ST	Q02156	PRKCE	Q02156	PRKCE	S368	R372Q	372	Missense	distal	4	no	18.283	17.753	EPSD;PhosphoSitePlus	COSMIC	13.948	Down-regulation
AGC_PKC_PKCh_PRKCE_ST	Q02156	PRKCE	Q02156	PRKCE	S380	A378T	378	Missense	proximal	-2	no	14.241	13.648	EPSD	COSMIC	13.948	Loss
AGC_PKC_PKCh_PRKCE_ST	Q96A00	PPP1R14A	Q02156	PRKCE	T38	V39I	39	Missense	proximal	1	no	20.543	21.577	PhosphoSitePlus	COSMIC;CCLE	13.948	Up-regulation
AGC_PKC_PKCh_PRKCE_ST	Q96A00	PPP1R14A	Q02156	PRKCE	T38	D42N	42	Missense	distal	4	no	20.543	19.935	PhosphoSitePlus	COSMIC	13.948	Down-regulation
AGC_PKC_PKCh_PRKCE_ST	Q96A00	PPP1R14A	Q02156	PRKCE	S128	P122L	122	Missense	distal	-6	no	13.985	13.965	EPSD	COSMIC	13.948	Down-regulation
AGC_PKC_PKCh_PRKCE_ST	Q96A00	PPP1R14A	Q02156	PRKCE	S134	S136N	136	Missense	proximal	2	no	15.057	15.721	EPSD	COSMIC	13.948	Up-regulation
AGC_PKC_PKCh_PRKCE_ST	Q96A00	PPP1R14A	Q02156	PRKCE	S134	L138F	138	Missense	distal	4	no	15.057	16.070	EPSD	COSMIC	13.948	Up-regulation
AGC_PKC_PKCh_PRKCE_ST	Q96A00	PPP1R14A	Q02156	PRKCE	S134	R141W	141	Missense	distal	7	no	15.057	12.562	EPSD	COSMIC;GDSC	13.948	Loss
AGC_PKC_PKCh_PRKCE_ST	Q96A00	PPP1R14A	Q02156	PRKCE	S136	S136N	136	Missense	central	0	yes	17.416	0.000	EPSD	COSMIC	13.948	Loss
AGC_PKC_PKCh_PRKCE_ST	Q96A00	PPP1R14A	Q02156	PRKCE	S136	L138F	138	Missense	proximal	2	no	17.416	15.893	EPSD	COSMIC	13.948	Down-regulation
AGC_PKC_PKCh_PRKCE_ST	Q96A00	PPP1R14A	Q02156	PRKCE	S136	R141W	141	Missense	distal	5	no	17.416	18.185	EPSD	COSMIC;GDSC	13.948	Up-regulation
AGC_PKC_PKCh_PRKCE_ST	O94925	GLS	Q02156	PRKCE	S118	N117S	117	Missense	proximal	-1	no	16.628	16.753	EPSD	COSMIC	13.948	Up-regulation
AGC_PKC_PKCh_PRKCE_ST	O94925	GLS	Q02156	PRKCE	S314	P313T	313	Missense	proximal	-1	no	16.352	16.395	PhosphoSitePlus	COSMIC	13.948	Up-regulation
AGC_PKC_PKCh_PRKCE_ST	P46940	IQGAP1	Q02156	PRKCE	S91	K88T	88	Missense	distal	-3	no	18.534	13.941	EPSD	COSMIC	13.948	Loss
AGC_PKC_PKCh_PRKCE_ST	P46940	IQGAP1	Q02156	PRKCE	S91	V90M	90	Missense	proximal	-1	no	18.534	19.857	EPSD	COSMIC	13.948	Up-regulation
AGC_PKC_PKCh_PRKCE_ST	P46940	IQGAP1	Q02156	PRKCE	S91	L92P	92	Missense	proximal	1	no	18.534	17.170	EPSD	COSMIC	13.948	Down-regulation
AGC_PKC_PKCh_PRKCE_ST	P46940	IQGAP1	Q02156	PRKCE	S280	A273S	273	Missense	distal	-7	no	17.797	17.858	EPSD	COSMIC	13.948	Up-regulation
AGC_PKC_PKCh_PRKCE_ST	P46940	IQGAP1	Q02156	PRKCE	S644	A645V	645	Missense	proximal	1	no	13.925	14.346	EPSD	COSMIC	13.948	Gain
AGC_PKC_PKCh_PRKCE_ST	P46940	IQGAP1	Q02156	PRKCE	S934	S932F	932	Missense	proximal	-2	no	15.531	13.666	EPSD	COSMIC	13.948	Loss
AGC_PKC_PKCh_PRKCE_ST	P46940	IQGAP1	Q02156	PRKCE	S1237	A1235T	1235	Missense	proximal	-2	no	14.075	13.483	EPSD	COSMIC	13.948	Loss
AGC_PKC_PKCh_PRKCE_ST	P46940	IQGAP1	Q02156	PRKCE	S1443	V1444I	1444	Missense	proximal	1	no	23.160	24.194	PhosphoSitePlus	COSMIC	13.948	Up-regulation
AGC_PKC_PKCh_PRKCE_ST	P46940	IQGAP1	Q02156	PRKCE	S1443	N1449K	1449	Missense	distal	6	no	23.160	23.206	PhosphoSitePlus	COSMIC	13.948	Up-regulation
AGC_PKC_PKCh_PRKCE_ST	P46940	IQGAP1	Q02156	PRKCE	S1448	V1444I	1444	Missense	distal	-4	no	13.792	13.960	EPSD	COSMIC	13.948	Gain
AGC_PKC_PKCh_PRKCE_ST	P46940	IQGAP1	Q02156	PRKCE	S1448	N1449K	1449	Missense	proximal	1	no	13.792	16.411	EPSD	COSMIC	13.948	Gain
AGC_PKC_PKCh_PRKCE_ST	P05091	ALDH2	Q02156	PRKCE	T202	A199P	199	Missense	distal	-3	no	14.339	10.416	PhosphoSitePlus;EPSD	COSMIC	13.948	Loss
AGC_PKC_PKCh_PRKCE_ST	P05091	ALDH2	Q02156	PRKCE	T202	N204D	204	Missense	proximal	2	no	14.339	14.743	PhosphoSitePlus;EPSD	COSMIC	13.948	Up-regulation
AGC_PKC_PKCh_PRKCE_ST	P05091	ALDH2	Q02156	PRKCE	T202	L200F	200	Missense	proximal	-2	no	14.339	14.767	PhosphoSitePlus;EPSD	COSMIC	13.948	Up-regulation
AGC_PKC_PKCh_PRKCE_ST	P05091	ALDH2	Q02156	PRKCE	T202	G203E	203	Missense	proximal	1	no	14.339	12.444	PhosphoSitePlus;EPSD	COSMIC	13.948	Loss
AGC_PKC_PKCh_PRKCE_ST	P05091	ALDH2	Q02156	PRKCE	S276	V269I	269	Missense	distal	-7	no	15.744	15.775	EPSD	COSMIC	13.948	Up-regulation
AGC_PKC_PKCh_PRKCE_ST	P05091	ALDH2	Q02156	PRKCE	T283	G288E	288	Missense	distal	5	no	14.529	14.612	EPSD	COSMIC;CCLE	13.948	Up-regulation
AGC_PKC_PKCh_PRKCE_ST	P05091	ALDH2	Q02156	PRKCE	T283	G287V	287	Missense	distal	4	no	14.529	14.010	EPSD	COSMIC;GDSC;CCLE	13.948	Down-regulation
AGC_PKC_PKCh_PRKCE_ST	P05091	ALDH2	Q02156	PRKCE	S296	M295I	295	Missense	proximal	-1	no	14.408	12.840	EPSD;PhosphoSitePlus	COSMIC	13.948	Loss
AGC_PKC_PKCh_PRKCE_ST	P05091	ALDH2	Q02156	PRKCE	S296	W302L	302	Missense	distal	6	no	14.408	13.811	EPSD;PhosphoSitePlus	COSMIC	13.948	Loss
AGC_PKC_PKCh_PRKCE_ST	P05091	ALDH2	Q02156	PRKCE	S296	I294V	294	Missense	proximal	-2	no	14.408	15.297	EPSD;PhosphoSitePlus	COSMIC	13.948	Up-regulation
AGC_PKC_PKCh_PRKCE_ST	P05091	ALDH2	Q02156	PRKCE	S296	P291L	291	Missense	distal	-5	no	14.408	14.403	EPSD;PhosphoSitePlus	COSMIC	13.948	Down-regulation
AGC_PKC_PKCh_PRKCE_ST	P05091	ALDH2	Q02156	PRKCE	T376	E380K	380	Missense	distal	4	no	13.244	14.823	EPSD	COSMIC	13.948	Gain
AGC_PKC_PKCh_PRKCE_ST	P05091	ALDH2	Q02156	PRKCE	T429	F427S	427	Missense	proximal	-2	no	12.813	14.678	EPSD;PhosphoSitePlus	COSMIC	13.948	Gain
AGC_PKC_PKCh_PRKCE_ST	Q15139	PRKD1	Q02156	PRKCE	S237	S239L	239	Missense	proximal	2	no	16.139	14.941	EPSD	COSMIC	13.948	Down-regulation
AGC_PKC_PKCh_PRKCE_ST	Q15139	PRKD1	Q02156	PRKCE	S401	R394K	394	Missense	distal	-7	no	13.976	13.756	EPSD	COSMIC	13.948	Loss
AGC_PKC_PKCh_PRKCE_ST	Q15139	PRKD1	Q02156	PRKCE	S401	S397N	397	Missense	distal	-4	no	13.976	13.973	EPSD	COSMIC	13.948	Down-regulation
AGC_PKC_PKCh_PRKCE_ST	Q15139	PRKD1	Q02156	PRKCE	S401	N402T	402	Missense	proximal	1	no	13.976	14.641	EPSD	COSMIC	13.948	Up-regulation
AGC_PKC_PKCh_PRKCE_ST	Q15139	PRKD1	Q02156	PRKCE	S412	S412F	412	Missense	central	0	yes	14.595	0.000	EPSD	COSMIC	13.948	Loss
AGC_PKC_PKCh_PRKCE_ST	Q15139	PRKD1	Q02156	PRKCE	S412	Q411H	411	Missense	proximal	-1	no	14.595	13.558	EPSD	COSMIC	13.948	Loss
AGC_PKC_PKCh_PRKCE_ST	Q15139	PRKD1	Q02156	PRKCE	S412	V413D	413	Missense	proximal	1	no	14.595	14.981	EPSD	COSMIC	13.948	Up-regulation
AGC_PKC_PKCh_PRKCE_ST	Q15139	PRKD1	Q02156	PRKCE	S412	Q411L	411	Missense	proximal	-1	no	14.595	14.152	EPSD	COSMIC	13.948	Down-regulation
AGC_PKC_PKCh_PRKCE_ST	Q15139	PRKD1	Q02156	PRKCE	S738	G735V	735	Missense	distal	-3	no	20.516	21.464	PhosphoSitePlus;EPSD	COSMIC	13.948	Up-regulation
AGC_PKC_PKCh_PRKCE_ST	Q15139	PRKD1	Q02156	PRKCE	S738	V743L	743	Missense	distal	5	no	20.516	20.466	PhosphoSitePlus;EPSD	COSMIC	13.948	Down-regulation
AGC_PKC_PKCh_PRKCE_ST	Q15139	PRKD1	Q02156	PRKCE	S738	A731D	731	Missense	distal	-7	no	20.516	20.603	PhosphoSitePlus;EPSD	COSMIC	13.948	Up-regulation
AGC_PKC_PKCh_PRKCE_ST	Q15139	PRKD1	Q02156	PRKCE	S742	A748T	748	Missense	distal	6	no	17.260	17.507	EPSD;PhosphoSitePlus	COSMIC	13.948	Up-regulation
AGC_PKC_PKCh_PRKCE_ST	Q15139	PRKD1	Q02156	PRKCE	S742	G735V	735	Missense	distal	-7	no	17.260	17.095	EPSD;PhosphoSitePlus	COSMIC	13.948	Down-regulation
AGC_PKC_PKCh_PRKCE_ST	Q15139	PRKD1	Q02156	PRKCE	S742	V743L	743	Missense	proximal	1	no	17.260	17.773	EPSD;PhosphoSitePlus	COSMIC	13.948	Up-regulation
AGC_PKC_PKCh_PRKCE_ST	Q15139	PRKD1	Q02156	PRKCE	S742	T746I	746	Missense	distal	4	no	17.260	16.957	EPSD;PhosphoSitePlus	COSMIC	13.948	Down-regulation
AGC_PKC_PKCh_PRKCE_ST	Q15139	PRKD1	Q02156	PRKCE	S829	Y828H	828	Missense	proximal	-1	no	18.738	17.255	EPSD	COSMIC	13.948	Down-regulation
AGC_PKC_PKCh_PRKCE_ST	Q15139	PRKD1	Q02156	PRKCE	S910	V909D	909	Missense	proximal	-1	no	14.354	14.547	EPSD	COSMIC	13.948	Up-regulation
AGC_PKC_PKCh_PRKCE_ST	P00533	EGFR	Q02156	PRKCE	S227	G221V	221	Missense	distal	-6	no	14.792	14.794	EPSD	COSMIC	13.948	Up-regulation
AGC_PKC_PKCh_PRKCE_ST	P00533	EGFR	Q02156	PRKCE	S227	R222H	222	Missense	distal	-5	no	14.792	14.829	EPSD	COSMIC	13.948	Up-regulation
AGC_PKC_PKCh_PRKCE_ST	P00533	EGFR	Q02156	PRKCE	S227	G221W	221	Missense	distal	-6	no	14.792	14.601	EPSD	COSMIC	13.948	Down-regulation
AGC_PKC_PKCh_PRKCE_ST	P00533	EGFR	Q02156	PRKCE	S227	S227Y	227	Missense	central	0	yes	14.792	0.000	EPSD	COSMIC	13.948	Loss
AGC_PKC_PKCh_PRKCE_ST	P00533	EGFR	Q02156	PRKCE	S227	G225C	225	Missense	proximal	-2	no	14.792	13.879	EPSD	COSMIC	13.948	Loss
AGC_PKC_PKCh_PRKCE_ST	P00533	EGFR	Q02156	PRKCE	S227	S220F	220	Missense	distal	-7	no	14.792	14.515	EPSD	COSMIC	13.948	Down-regulation
AGC_PKC_PKCh_PRKCE_ST	P00533	EGFR	Q02156	PRKCE	S227	C231S	231	Missense	distal	4	no	14.792	17.074	EPSD	COSMIC	13.948	Up-regulation
AGC_PKC_PKCh_PRKCE_ST	P00533	EGFR	Q02156	PRKCE	S246	P243S	243	Missense	distal	-3	no	11.189	14.506	EPSD	COSMIC	13.948	Gain
AGC_PKC_PKCh_PRKCE_ST	P00533	EGFR	Q02156	PRKCE	S246	P243A	243	Missense	distal	-3	no	11.189	15.111	EPSD	COSMIC	13.948	Gain
AGC_PKC_PKCh_PRKCE_ST	P00533	EGFR	Q02156	PRKCE	S457	I462M	462	Missense	distal	5	no	15.828	15.667	EPSD	COSMIC	13.948	Down-regulation
AGC_PKC_PKCh_PRKCE_ST	P00533	EGFR	Q02156	PRKCE	S457	G459S	459	Missense	proximal	2	no	15.828	14.303	EPSD	COSMIC	13.948	Down-regulation
AGC_PKC_PKCh_PRKCE_ST	P00533	EGFR	Q02156	PRKCE	S457	V461M	461	Missense	distal	4	no	15.828	14.203	EPSD	COSMIC	13.948	Down-regulation
AGC_PKC_PKCh_PRKCE_ST	P00533	EGFR	Q02156	PRKCE	S457	R451H	451	Missense	distal	-6	no	15.828	15.651	EPSD	COSMIC	13.948	Down-regulation
AGC_PKC_PKCh_PRKCE_ST	P00533	EGFR	Q02156	PRKCE	S457	G459D	459	Missense	proximal	2	no	15.828	15.371	EPSD	COSMIC	13.948	Down-regulation
AGC_PKC_PKCh_PRKCE_ST	P00533	EGFR	Q02156	PRKCE	S457	R451C	451	Missense	distal	-6	no	15.828	15.720	EPSD	COSMIC	13.948	Down-regulation
AGC_PKC_PKCh_PRKCE_ST	P00533	EGFR	Q02156	PRKCE	S457	R451F	451	Missense	distal	-6	no	15.828	15.671	EPSD	COSMIC	13.948	Down-regulation
AGC_PKC_PKCh_PRKCE_ST	P00533	EGFR	Q02156	PRKCE	S457	L453F	453	Missense	distal	-4	no	15.828	15.766	EPSD	COSMIC	13.948	Down-regulation
AGC_PKC_PKCh_PRKCE_ST	P00533	EGFR	Q02156	PRKCE	S457	K454N	454	Missense	distal	-3	no	15.828	8.455	EPSD	COSMIC	13.948	Loss
AGC_PKC_PKCh_PRKCE_ST	P00533	EGFR	Q02156	PRKCE	S457	G459A	459	Missense	proximal	2	no	15.828	13.572	EPSD	COSMIC	13.948	Loss
AGC_PKC_PKCh_PRKCE_ST	P00533	EGFR	Q02156	PRKCE	S645	I643V	643	Missense	proximal	-2	no	13.320	14.209	EPSD	COSMIC	13.948	Gain
AGC_PKC_PKCh_PRKCE_ST	P00533	EGFR	Q02156	PRKCE	S645	G652R	652	Missense	distal	7	no	13.320	14.002	EPSD	COSMIC	13.948	Gain
AGC_PKC_PKCh_PRKCE_ST	P00533	EGFR	Q02156	PRKCE	T678	R680Q	680	Missense	proximal	2	no	15.967	10.734	PhosphoSitePlus	COSMIC	13.948	Loss
AGC_PKC_PKCh_PRKCE_ST	P00533	EGFR	Q02156	PRKCE	T678	V674F	674	Missense	distal	-4	no	15.967	15.940	PhosphoSitePlus	COSMIC	13.948	Down-regulation
AGC_PKC_PKCh_PRKCE_ST	P00533	EGFR	Q02156	PRKCE	T678	R675Q	675	Missense	distal	-3	no	15.967	10.400	PhosphoSitePlus	COSMIC;GDSC	13.948	Loss
AGC_PKC_PKCh_PRKCE_ST	P00533	EGFR	Q02156	PRKCE	T678	R680W	680	Missense	proximal	2	no	15.967	3.294	PhosphoSitePlus	COSMIC	13.948	Loss
AGC_PKC_PKCh_PRKCE_ST	P00533	EGFR	Q02156	PRKCE	T678	H672Y	672	Missense	distal	-6	no	15.967	16.080	PhosphoSitePlus	COSMIC	13.948	Up-regulation
AGC_PKC_PKCh_PRKCE_ST	P00533	EGFR	Q02156	PRKCE	T678	R680G	680	Missense	proximal	2	no	15.967	11.054	PhosphoSitePlus	COSMIC	13.948	Loss
AGC_PKC_PKCh_PRKCE_ST	P00533	EGFR	Q02156	PRKCE	T678	K676R	676	Missense	proximal	-2	no	15.967	15.532	PhosphoSitePlus	COSMIC	13.948	Down-regulation
AGC_PKC_PKCh_PRKCE_ST	P00533	EGFR	Q02156	PRKCE	T678	R671C	671	Missense	distal	-7	no	15.967	15.862	PhosphoSitePlus	COSMIC	13.948	Down-regulation
AGC_PKC_PKCh_PRKCE_ST	P00533	EGFR	Q02156	PRKCE	T678	R677C	677	Missense	proximal	-1	no	15.967	15.610	PhosphoSitePlus	COSMIC;GDSC;CCLE	13.948	Down-regulation
AGC_PKC_PKCh_PRKCE_ST	P00533	EGFR	Q02156	PRKCE	T678	R671H	671	Missense	distal	-7	no	15.967	15.502	PhosphoSitePlus	COSMIC	13.948	Down-regulation
AGC_PKC_PKCh_PRKCE_ST	P00533	EGFR	Q02156	PRKCE	S752	L747P	747	Missense	distal	-5	no	14.001	14.006	EPSD	COSMIC	13.948	Up-regulation
AGC_PKC_PKCh_PRKCE_ST	P00533	EGFR	Q02156	PRKCE	S752	L747F	747	Missense	distal	-5	no	14.001	13.995	EPSD	COSMIC	13.948	Down-regulation
AGC_PKC_PKCh_PRKCE_ST	P00533	EGFR	Q02156	PRKCE	S752	L747H	747	Missense	distal	-5	no	14.001	14.025	EPSD	COSMIC	13.948	Up-regulation
AGC_PKC_PKCh_PRKCE_ST	P00533	EGFR	Q02156	PRKCE	S752	L747S	747	Missense	distal	-5	no	14.001	14.026	EPSD	COSMIC	13.948	Up-regulation
AGC_PKC_PKCh_PRKCE_ST	P00533	EGFR	Q02156	PRKCE	S752	A750P	750	Missense	proximal	-2	no	14.001	15.057	EPSD	COSMIC	13.948	Up-regulation
AGC_PKC_PKCh_PRKCE_ST	P00533	EGFR	Q02156	PRKCE	S752	R748K	748	Missense	distal	-4	no	14.001	14.272	EPSD	COSMIC	13.948	Up-regulation
AGC_PKC_PKCh_PRKCE_ST	P00533	EGFR	Q02156	PRKCE	S752	I759V	759	Missense	distal	7	no	14.001	13.507	EPSD	COSMIC	13.948	Loss
AGC_PKC_PKCh_PRKCE_ST	P00533	EGFR	Q02156	PRKCE	S752	K754Q	754	Missense	proximal	2	no	14.001	8.087	EPSD	COSMIC	13.948	Loss
AGC_PKC_PKCh_PRKCE_ST	P00533	EGFR	Q02156	PRKCE	S752	T751A	751	Missense	proximal	-1	no	14.001	14.193	EPSD	COSMIC	13.948	Up-regulation
AGC_PKC_PKCh_PRKCE_ST	P00533	EGFR	Q02156	PRKCE	S752	E758G	758	Missense	distal	6	no	14.001	14.216	EPSD	COSMIC	13.948	Up-regulation
AGC_PKC_PKCh_PRKCE_ST	P00533	EGFR	Q02156	PRKCE	S752	K757N	757	Missense	distal	5	no	14.001	14.053	EPSD	COSMIC	13.948	Up-regulation
AGC_PKC_PKCh_PRKCE_ST	P00533	EGFR	Q02156	PRKCE	S752	S752Y	752	Missense	central	0	yes	14.001	0.000	EPSD	COSMIC	13.948	Loss
AGC_PKC_PKCh_PRKCE_ST	P00533	EGFR	Q02156	PRKCE	S752	T751I	751	Missense	proximal	-1	no	14.001	13.752	EPSD	COSMIC;GDSC;CCLE	13.948	Loss
AGC_PKC_PKCh_PRKCE_ST	P00533	EGFR	Q02156	PRKCE	S752	E746V	746	Missense	distal	-6	no	14.001	14.020	EPSD	COSMIC	13.948	Up-regulation
AGC_PKC_PKCh_PRKCE_ST	P00533	EGFR	Q02156	PRKCE	S752	A750T	750	Missense	proximal	-2	no	14.001	13.409	EPSD	COSMIC	13.948	Loss
AGC_PKC_PKCh_PRKCE_ST	P00533	EGFR	Q02156	PRKCE	S752	S752F	752	Missense	central	0	yes	14.001	0.000	EPSD	COSMIC	13.948	Loss
AGC_PKC_PKCh_PRKCE_ST	P00533	EGFR	Q02156	PRKCE	S752	E746A	746	Missense	distal	-6	no	14.001	13.978	EPSD	COSMIC;GDSC	13.948	Down-regulation
AGC_PKC_PKCh_PRKCE_ST	P00533	EGFR	Q02156	PRKCE	S752	A755D	755	Missense	distal	3	no	14.001	14.312	EPSD	COSMIC;CCLE	13.948	Up-regulation
AGC_PKC_PKCh_PRKCE_ST	P00533	EGFR	Q02156	PRKCE	S752	K754R	754	Missense	proximal	2	no	14.001	13.319	EPSD	COSMIC	13.948	Loss
AGC_PKC_PKCh_PRKCE_ST	P00533	EGFR	Q02156	PRKCE	S752	E749K	749	Missense	distal	-3	no	14.001	21.127	EPSD	COSMIC	13.948	Up-regulation
AGC_PKC_PKCh_PRKCE_ST	P00533	EGFR	Q02156	PRKCE	S752	T751L	751	Missense	proximal	-1	no	14.001	14.023	EPSD	COSMIC	13.948	Up-regulation
AGC_PKC_PKCh_PRKCE_ST	P00533	EGFR	Q02156	PRKCE	S752	E758K	758	Missense	distal	6	no	14.001	14.296	EPSD	COSMIC	13.948	Up-regulation
AGC_PKC_PKCh_PRKCE_ST	P00533	EGFR	Q02156	PRKCE	S752	K745R	745	Missense	distal	-7	no	14.001	14.221	EPSD	COSMIC	13.948	Up-regulation
AGC_PKC_PKCh_PRKCE_ST	P00533	EGFR	Q02156	PRKCE	S752	A755T	755	Missense	distal	3	no	14.001	13.598	EPSD	COSMIC	13.948	Loss
AGC_PKC_PKCh_PRKCE_ST	P00533	EGFR	Q02156	PRKCE	S752	K754A	754	Missense	proximal	2	no	14.001	6.150	EPSD	COSMIC	13.948	Loss
AGC_PKC_PKCh_PRKCE_ST	P00533	EGFR	Q02156	PRKCE	S752	N756S	756	Missense	distal	4	no	14.001	14.910	EPSD	COSMIC	13.948	Up-regulation
AGC_PKC_PKCh_PRKCE_ST	P00533	EGFR	Q02156	PRKCE	S752	N756Y	756	Missense	distal	4	no	14.001	13.584	EPSD	COSMIC	13.948	Loss
AGC_PKC_PKCh_PRKCE_ST	P00533	EGFR	Q02156	PRKCE	S752	K757R	757	Missense	distal	5	no	14.001	13.750	EPSD	COSMIC	13.948	Loss
AGC_PKC_PKCh_PRKCE_ST	P00533	EGFR	Q02156	PRKCE	S752	A755G	755	Missense	distal	3	no	14.001	14.343	EPSD	COSMIC	13.948	Up-regulation
AGC_PKC_PKCh_PRKCE_ST	P00533	EGFR	Q02156	PRKCE	S752	E746G	746	Missense	distal	-6	no	14.001	14.018	EPSD	COSMIC	13.948	Up-regulation
AGC_PKC_PKCh_PRKCE_ST	P00533	EGFR	Q02156	PRKCE	S752	E749V	749	Missense	distal	-3	no	14.001	14.799	EPSD	COSMIC	13.948	Up-regulation
AGC_PKC_PKCh_PRKCE_ST	P00533	EGFR	Q02156	PRKCE	S752	E749G	749	Missense	distal	-3	no	14.001	13.851	EPSD	COSMIC	13.948	Loss
AGC_PKC_PKCh_PRKCE_ST	P00533	EGFR	Q02156	PRKCE	S752	S752P	752	Missense	central	0	yes	14.001	0.000	EPSD	COSMIC	13.948	Loss
AGC_PKC_PKCh_PRKCE_ST	P00533	EGFR	Q02156	PRKCE	S752	E758D	758	Missense	distal	6	no	14.001	13.961	EPSD	COSMIC	13.948	Down-regulation
AGC_PKC_PKCh_PRKCE_ST	P00533	EGFR	Q02156	PRKCE	S752	K745T	745	Missense	distal	-7	no	14.001	13.812	EPSD	COSMIC	13.948	Loss
AGC_PKC_PKCh_PRKCE_ST	P00533	EGFR	Q02156	PRKCE	S752	E746K	746	Missense	distal	-6	no	14.001	14.078	EPSD	COSMIC;GDSC	13.948	Up-regulation
AGC_PKC_PKCh_PRKCE_ST	P00533	EGFR	Q02156	PRKCE	S752	A755V	755	Missense	distal	3	no	14.001	14.477	EPSD	COSMIC	13.948	Up-regulation
AGC_PKC_PKCh_PRKCE_ST	P00533	EGFR	Q02156	PRKCE	S752	L747V	747	Missense	distal	-5	no	14.001	13.994	EPSD	COSMIC	13.948	Down-regulation
AGC_PKC_PKCh_PRKCE_ST	P00533	EGFR	Q02156	PRKCE	S752	T751P	751	Missense	proximal	-1	no	14.001	13.959	EPSD	COSMIC	13.948	Down-regulation
AGC_PKC_PKCh_PRKCE_ST	P00533	EGFR	Q02156	PRKCE	S752	R748I	748	Missense	distal	-4	no	14.001	14.365	EPSD	COSMIC	13.948	Up-regulation
AGC_PKC_PKCh_PRKCE_ST	P00533	EGFR	Q02156	PRKCE	S752	K757M	757	Missense	distal	5	no	14.001	13.982	EPSD	COSMIC	13.948	Down-regulation
AGC_PKC_PKCh_PRKCE_ST	P00533	EGFR	Q02156	PRKCE	S752	P753F	753	Missense	proximal	1	no	14.001	16.466	EPSD	COSMIC	13.948	Up-regulation
AGC_PKC_PKCh_PRKCE_ST	P00533	EGFR	Q02156	PRKCE	S768	C775Y	775	Missense	distal	7	no	13.252	14.032	EPSD	COSMIC	13.948	Gain
AGC_PKC_PKCh_PRKCE_ST	P00533	EGFR	Q02156	PRKCE	S1064	F1065L	1065	Missense	proximal	1	no	14.638	13.536	EPSD	COSMIC	13.948	Loss
AGC_PKC_PKCh_PRKCE_ST	P00533	EGFR	Q02156	PRKCE	S1064	C1058Y	1058	Missense	distal	-6	no	14.638	14.683	EPSD	COSMIC	13.948	Up-regulation
AGC_PKC_PKCh_PRKCE_ST	P00533	EGFR	Q02156	PRKCE	S1064	P1059L	1059	Missense	distal	-5	no	14.638	14.633	EPSD	COSMIC	13.948	Down-regulation
AGC_PKC_PKCh_PRKCE_ST	P00533	EGFR	Q02156	PRKCE	S1064	Q1067L	1067	Missense	distal	3	no	14.638	14.418	EPSD	COSMIC	13.948	Down-regulation
AGC_PKC_PKCh_PRKCE_ST	P00533	EGFR	Q02156	PRKCE	S1064	Y1069C	1069	Missense	distal	5	no	14.638	14.709	EPSD	COSMIC;GDSC;CCLE	13.948	Up-regulation
AGC_PKC_PKCh_PRKCE_ST	P00533	EGFR	Q02156	PRKCE	S1064	S1064G	1064	Missense	central	0	yes	14.638	0.000	EPSD	COSMIC	13.948	Loss
AGC_PKC_PKCh_PRKCE_ST	P00533	EGFR	Q02156	PRKCE	S1064	S1071L	1071	Missense	distal	7	no	14.638	14.180	EPSD	COSMIC	13.948	Down-regulation
AGC_PKC_PKCh_PRKCE_ST	P00533	EGFR	Q02156	PRKCE	S1064	S1064R	1064	Missense	central	0	yes	14.638	0.000	EPSD	COSMIC	13.948	Loss
AGC_PKC_PKCh_PRKCE_ST	P00533	EGFR	Q02156	PRKCE	S1064	S1070T	1070	Missense	distal	6	no	14.638	14.694	EPSD	COSMIC	13.948	Up-regulation
AGC_PKC_PKCh_PRKCE_ST	P00533	EGFR	Q02156	PRKCE	S1064	S1064N	1064	Missense	central	0	yes	14.638	0.000	EPSD	COSMIC	13.948	Loss
AGC_PKC_PKCh_PRKCE_ST	P00533	EGFR	Q02156	PRKCE	S1190	G1189D	1189	Missense	proximal	-1	no	15.423	15.010	EPSD	COSMIC	13.948	Down-regulation
AGC_PKC_PKCh_PRKCE_ST	P00533	EGFR	Q02156	PRKCE	S1190	K1188T	1188	Missense	proximal	-2	no	15.423	12.667	EPSD	COSMIC	13.948	Loss
AGC_PKC_PKCh_PRKCE_ST	P00533	EGFR	Q02156	PRKCE	S1190	K1188E	1188	Missense	proximal	-2	no	15.423	13.497	EPSD	COSMIC	13.948	Loss
AGC_PKC_PKCh_PRKCE_ST	P00533	EGFR	Q02156	PRKCE	S1190	N1184D	1184	Missense	distal	-6	no	15.423	15.503	EPSD	COSMIC	13.948	Up-regulation
AGC_PKC_PKCh_PRKCE_ST	P00533	EGFR	Q02156	PRKCE	S1190	G1185S	1185	Missense	distal	-5	no	15.423	15.444	EPSD	COSMIC	13.948	Up-regulation
AGC_PKC_PKCh_PRKCE_ST	P00533	EGFR	Q02156	PRKCE	T1191	G1189D	1189	Missense	proximal	-2	no	16.207	14.806	EPSD	COSMIC	13.948	Down-regulation
AGC_PKC_PKCh_PRKCE_ST	P00533	EGFR	Q02156	PRKCE	T1191	K1188T	1188	Missense	distal	-3	no	16.207	11.614	EPSD	COSMIC	13.948	Loss
AGC_PKC_PKCh_PRKCE_ST	P00533	EGFR	Q02156	PRKCE	T1191	K1188E	1188	Missense	distal	-3	no	16.207	9.080	EPSD	COSMIC	13.948	Loss
AGC_PKC_PKCh_PRKCE_ST	P00533	EGFR	Q02156	PRKCE	T1191	N1184D	1184	Missense	distal	-7	no	16.207	16.306	EPSD	COSMIC	13.948	Up-regulation
AGC_PKC_PKCh_PRKCE_ST	P00533	EGFR	Q02156	PRKCE	T1191	G1185S	1185	Missense	distal	-6	no	16.207	16.189	EPSD	COSMIC	13.948	Down-regulation
AGC_PKC_PKCh_PRKCE_ST	P00533	EGFR	Q02156	PRKCE	S1204	R1199M	1199	Missense	distal	-5	no	19.460	19.494	EPSD	COSMIC	13.948	Up-regulation
AGC_PKC_PKCh_PRKCE_ST	P00533	EGFR	Q02156	PRKCE	S1204	S1204R	1204	Missense	central	0	yes	19.460	0.000	EPSD	COSMIC	13.948	Loss
AGC_PKC_PKCh_PRKCE_ST	P00533	EGFR	Q02156	PRKCE	S1204	A1201T	1201	Missense	distal	-3	no	19.460	19.049	EPSD	COSMIC	13.948	Down-regulation
AGC_PKC_PKCh_PRKCE_ST	P00533	EGFR	Q02156	PRKCE	S1204	F1207C	1207	Missense	distal	3	no	19.460	19.334	EPSD	COSMIC	13.948	Down-regulation
AGC_PKC_PKCh_PRKCE_ST	P00533	EGFR	Q02156	PRKCE	S1204	R1199T	1199	Missense	distal	-5	no	19.460	19.473	EPSD	COSMIC	13.948	Up-regulation
AGC_PKC_PKCh_PRKCE_ST	P00533	EGFR	Q02156	PRKCE	S1204	V1200I	1200	Missense	distal	-4	no	19.460	19.628	EPSD	COSMIC	13.948	Up-regulation
AGC_PKC_PKCh_PRKCE_ST	Q9BR76	CORO1B	Q02156	PRKCE	S2	R8W	8	Missense	distal	6	no	19.654	20.689	PhosphoSitePlus	COSMIC	13.948	Up-regulation
AGC_PKC_PKCh_PRKCE_ST	Q9BR76	CORO1B	Q02156	PRKCE	S2	Q9H	9	Missense	distal	7	no	19.654	18.902	PhosphoSitePlus	COSMIC	13.948	Down-regulation
AGC_PKC_PKCh_PRKCE_ST	Q9BR76	CORO1B	Q02156	PRKCE	S2	R4H	4	Missense	proximal	2	no	19.654	12.682	PhosphoSitePlus	COSMIC;GDSC;CCLE	13.948	Loss
AGC_PKC_PKCh_PRKCE_ST	Q9BR76	CORO1B	Q02156	PRKCE	S199	V200M	200	Missense	proximal	1	no	15.204	15.672	EPSD	COSMIC;GDSC;CCLE	13.948	Up-regulation
AGC_PKC_PKCh_PRKCE_ST	Q9BR76	CORO1B	Q02156	PRKCE	S407	R402W	402	Missense	distal	-5	no	15.496	15.565	EPSD	COSMIC;GDSC;CCLE	13.948	Up-regulation
AGC_PKC_PKCh_PRKCE_ST	Q9BR76	CORO1B	Q02156	PRKCE	S407	R409H	409	Missense	proximal	2	no	15.496	8.524	EPSD	COSMIC;CCLE	13.948	Loss
AGC_PKC_PKCh_PRKCE_ST	Q9BR76	CORO1B	Q02156	PRKCE	S407	V411M	411	Missense	distal	4	no	15.496	13.871	EPSD	COSMIC	13.948	Loss
AGC_PKC_PKCh_PRKCE_ST	Q9BR76	CORO1B	Q02156	PRKCE	S407	S407N	407	Missense	central	0	yes	15.496	0.000	EPSD	COSMIC;CCLE	13.948	Loss
AGC_PKC_PKCh_PRKCE_ST	Q9BR76	CORO1B	Q02156	PRKCE	S423	A428P	428	Missense	distal	5	no	14.321	14.169	EPSD	COSMIC	13.948	Down-regulation
AGC_PKC_PKCh_PRKCE_ST	Q9BR76	CORO1B	Q02156	PRKCE	S423	S424P	424	Missense	proximal	1	no	14.321	13.192	EPSD	COSMIC	13.948	Loss
AGC_PKC_PKCh_PRKCE_ST	Q9BR76	CORO1B	Q02156	PRKCE	S423	S424Y	424	Missense	proximal	1	no	14.321	16.339	EPSD	COSMIC	13.948	Up-regulation
AGC_PKC_PKCh_PRKCE_ST	P23975	SLC6A2	Q02156	PRKCE	S259	G260E	260	Missense	proximal	1	no	17.719	15.824	PhosphoSitePlus	COSMIC	13.948	Down-regulation
AGC_PKC_PKCh_PRKCE_ST	P23975	SLC6A2	Q02156	PRKCE	S259	G255R	255	Missense	distal	-4	no	17.719	17.405	PhosphoSitePlus	COSMIC;CCLE	13.948	Down-regulation
AGC_PKC_PKCh_PRKCE_ST	P23975	SLC6A2	Q02156	PRKCE	S259	S259L	259	Missense	central	0	yes	17.719	0.000	PhosphoSitePlus	COSMIC	13.948	Loss
AGC_PKC_PKCh_PRKCE_ST	P23975	SLC6A2	Q02156	PRKCE	S259	G260R	260	Missense	proximal	1	no	17.719	17.521	PhosphoSitePlus	COSMIC	13.948	Down-regulation
AGC_PKC_PKCh_PRKCE_ST	P23975	SLC6A2	Q02156	PRKCE	S259	G255W	255	Missense	distal	-4	no	17.719	17.958	PhosphoSitePlus	COSMIC;GDSC;CCLE	13.948	Up-regulation
AGC_PKC_PKCh_PRKCE_ST	P23975	SLC6A2	Q02156	PRKCE	S259	W253C	253	Missense	distal	-6	no	17.719	17.901	PhosphoSitePlus	COSMIC	13.948	Up-regulation
AGC_PKC_PKCh_PRKCE_ST	Q5JXC2	MIIP	Q02156	PRKCE	S303	S307C	307	Missense	distal	4	no	18.987	16.706	PhosphoSitePlus	COSMIC	13.948	Down-regulation
AGC_PKC_PKCh_PRKCE_ST	P62491	RAB11A	Q02156	PRKCE	T203	V200A	200	Missense	distal	-3	no	13.295	15.442	EPSD	COSMIC	13.948	Gain
AGC_PKC_PKCh_PRKCE_ST	P20339	RAB5A	Q02156	PRKCE	T7	P12A	12	Missense	distal	5	no	17.367	17.519	PhosphoSitePlus	COSMIC	13.948	Up-regulation
AGC_PKC_PKCh_PRKCE_ST	P20339	RAB5A	Q02156	PRKCE	T7	R4P	4	Missense	distal	-3	no	17.367	9.281	PhosphoSitePlus	COSMIC	13.948	Loss
AGC_PKC_PKCh_PRKCE_ST	P20339	RAB5A	Q02156	PRKCE	S123	P124L	124	Missense	proximal	1	no	16.300	17.663	EPSD	COSMIC	13.948	Up-regulation
AGC_PKC_PKCh_PRKCE_ST	P20339	RAB5A	Q02156	PRKCE	S193	G190E	190	Missense	distal	-3	no	14.772	14.922	EPSD	COSMIC	13.948	Up-regulation
AGC_PKC_PKCh_PRKCE_ST	P20339	RAB5A	Q02156	PRKCE	S193	D200G	200	Missense	distal	7	no	14.772	13.666	EPSD	COSMIC	13.948	Loss
AGC_PKC_PKCh_PRKCE_ST	P20339	RAB5A	Q02156	PRKCE	T205	D200G	200	Missense	distal	-5	no	15.821	15.803	EPSD	COSMIC	13.948	Down-regulation
AGC_PKC_PKCh_PRKCE_ST	P05556	ITGB1	Q02156	PRKCE	S61	T60A	60	Missense	proximal	-1	no	16.146	16.338	EPSD	COSMIC	13.948	Up-regulation
AGC_PKC_PKCh_PRKCE_ST	P05556	ITGB1	Q02156	PRKCE	S209	Q211K	211	Missense	proximal	2	no	10.287	16.201	EPSD	COSMIC	13.948	Gain
AGC_PKC_PKCh_PRKCE_ST	P05556	ITGB1	Q02156	PRKCE	S327	I331F	331	Missense	distal	4	no	14.061	15.570	EPSD	COSMIC	13.948	Up-regulation
AGC_PKC_PKCh_PRKCE_ST	P05556	ITGB1	Q02156	PRKCE	S327	I334F	334	Missense	distal	7	no	14.061	14.510	EPSD	COSMIC;CCLE	13.948	Up-regulation
AGC_PKC_PKCh_PRKCE_ST	Q96GD4	AURKB	Q02156	PRKCE	S7	G13V	13	Missense	distal	6	no	18.330	18.532	EPSD	COSMIC	13.948	Up-regulation
AGC_PKC_PKCh_PRKCE_ST	Q96GD4	AURKB	Q02156	PRKCE	S227	M233V	233	Missense	distal	6	no	15.734	16.017	PhosphoSitePlus	COSMIC	13.948	Up-regulation
AGC_PKC_PKCh_PRKCE_ST	Q96GD4	AURKB	Q02156	PRKCE	S313	E314K	314	Missense	proximal	1	no	13.109	15.796	EPSD	COSMIC	13.948	Gain
AGC_PKC_PKCh_PRKCE_ST	Q96GD4	AURKB	Q02156	PRKCE	S331	R333W	333	Missense	proximal	2	no	27.336	14.662	EPSD	COSMIC	13.948	Down-regulation
AGC_PKC_PKCh_PRKCE_ST	Q96GD4	AURKB	Q02156	PRKCE	S331	P337L	337	Missense	distal	6	no	27.336	27.247	EPSD	COSMIC	13.948	Down-regulation
AGC_PKC_PKCh_PRKCE_ST	Q96GD4	AURKB	Q02156	PRKCE	S331	R333Q	333	Missense	proximal	2	no	27.336	22.103	EPSD	COSMIC	13.948	Down-regulation
AGC_PKC_PKCh_PRKCE_ST	Q96GD4	AURKB	Q02156	PRKCE	S331	W326R	326	Missense	distal	-5	no	27.336	27.267	EPSD	COSMIC	13.948	Down-regulation
AGC_PKC_PKCh_PRKCE_ST	Q96GD4	AURKB	Q02156	PRKCE	S331	R328Q	328	Missense	distal	-3	no	27.336	21.769	EPSD	COSMIC	13.948	Down-regulation
AGC_PKC_PKCh_PRKCE_ST	Q96GD4	AURKB	Q02156	PRKCE	S331	P337S	337	Missense	distal	6	no	27.336	27.231	EPSD	COSMIC	13.948	Down-regulation
AGC_PKC_PKCh_PRKCE_ST	Q96GD4	AURKB	Q02156	PRKCE	S331	A329V	329	Missense	proximal	-2	no	27.336	27.500	EPSD	COSMIC	13.948	Up-regulation
AGC_PKC_PKCh_PRKCE_ST	Q96GD4	AURKB	Q02156	PRKCE	S331	R333M	333	Missense	proximal	2	no	27.336	13.787	EPSD	COSMIC	13.948	Loss
AGC_PKC_PKCh_PRKCE_ST	Q96GD4	AURKB	Q02156	PRKCE	S331	R328W	328	Missense	distal	-3	no	27.336	16.338	EPSD	COSMIC	13.948	Down-regulation
AGC_PKC_PKCh_PRKCE_ST	Q96GD4	AURKB	Q02156	PRKCE	S331	R332W	332	Missense	proximal	1	no	27.336	25.625	EPSD	COSMIC	13.948	Down-regulation
AGC_PKC_PKCh_PRKCE_ST	Q96GD4	AURKB	Q02156	PRKCE	S331	W326L	326	Missense	distal	-5	no	27.336	27.279	EPSD	COSMIC	13.948	Down-regulation
AGC_PKC_PKCh_PRKCE_ST	P28329	CHAT	Q02156	PRKCE	S244	L248V	248	Missense	distal	4	no	16.939	18.161	EPSD	COSMIC	13.948	Up-regulation
AGC_PKC_PKCh_PRKCE_ST	P28329	CHAT	Q02156	PRKCE	S244	L248P	248	Missense	distal	4	no	16.939	17.442	EPSD	COSMIC	13.948	Up-regulation
AGC_PKC_PKCh_PRKCE_ST	P28329	CHAT	Q02156	PRKCE	S244	S240F	240	Missense	distal	-4	no	16.939	16.792	EPSD	COSMIC	13.948	Down-regulation
AGC_PKC_PKCh_PRKCE_ST	P28329	CHAT	Q02156	PRKCE	S244	L243F	243	Missense	proximal	-1	no	16.939	17.310	EPSD	COSMIC	13.948	Up-regulation
AGC_PKC_PKCh_PRKCE_ST	P28329	CHAT	Q02156	PRKCE	S244	D250N	250	Missense	distal	6	no	16.939	17.229	EPSD	COSMIC	13.948	Up-regulation
AGC_PKC_PKCh_PRKCE_ST	P28329	CHAT	Q02156	PRKCE	S244	S237N	237	Missense	distal	-7	no	16.939	16.865	EPSD	COSMIC	13.948	Down-regulation
AGC_PKC_PKCh_PRKCE_ST	P28329	CHAT	Q02156	PRKCE	T373	R375Q	375	Missense	proximal	2	no	16.395	11.162	EPSD	COSMIC	13.948	Loss
AGC_PKC_PKCh_PRKCE_ST	P28329	CHAT	Q02156	PRKCE	T373	K370R	370	Missense	distal	-3	no	16.395	16.377	EPSD	COSMIC	13.948	Down-regulation
AGC_PKC_PKCh_PRKCE_ST	P28329	CHAT	Q02156	PRKCE	T373	T366M	366	Missense	distal	-7	no	16.395	16.943	EPSD	COSMIC	13.948	Up-regulation
AGC_PKC_PKCh_PRKCE_ST	P28329	CHAT	Q02156	PRKCE	T373	V369M	369	Missense	distal	-4	no	16.395	16.439	EPSD	COSMIC	13.948	Up-regulation
AGC_PKC_PKCh_PRKCE_ST	P28329	CHAT	Q02156	PRKCE	T373	D376G	376	Missense	distal	3	no	16.395	16.425	EPSD	COSMIC	13.948	Up-regulation
AGC_PKC_PKCh_PRKCE_ST	P28329	CHAT	Q02156	PRKCE	S473	A479T	479	Missense	distal	6	no	15.176	15.423	EPSD	COSMIC	13.948	Up-regulation
AGC_PKC_PKCh_PRKCE_ST	P28329	CHAT	Q02156	PRKCE	S473	R466Q	466	Missense	distal	-7	no	15.176	14.995	EPSD	COSMIC	13.948	Down-regulation
AGC_PKC_PKCh_PRKCE_ST	P28329	CHAT	Q02156	PRKCE	S473	R466L	466	Missense	distal	-7	no	15.176	14.854	EPSD	COSMIC	13.948	Down-regulation
AGC_PKC_PKCh_PRKCE_ST	P28329	CHAT	Q02156	PRKCE	S473	P478S	478	Missense	distal	5	no	15.176	15.068	EPSD	COSMIC	13.948	Down-regulation
AGC_PKC_PKCh_PRKCE_ST	P28329	CHAT	Q02156	PRKCE	S473	S475G	475	Missense	proximal	2	no	15.176	16.701	EPSD	COSMIC	13.948	Up-regulation
AGC_PKC_PKCh_PRKCE_ST	P28329	CHAT	Q02156	PRKCE	S558	E555K	555	Missense	distal	-3	no	17.756	24.883	EPSD	COSMIC	13.948	Up-regulation
AGC_PKC_PKCh_PRKCE_ST	P28329	CHAT	Q02156	PRKCE	S558	A557T	557	Missense	proximal	-1	no	17.756	17.564	EPSD	COSMIC;GDSC	13.948	Down-regulation
AGC_PKC_PKCh_PRKCE_ST	P28329	CHAT	Q02156	PRKCE	S558	R560C	560	Missense	proximal	2	no	17.756	11.332	EPSD	COSMIC	13.948	Loss
AGC_PKC_PKCh_PRKCE_ST	P28329	CHAT	Q02156	PRKCE	S558	V551A	551	Missense	distal	-7	no	17.756	17.906	EPSD	COSMIC	13.948	Up-regulation
AGC_PKC_PKCh_PRKCE_ST	P28329	CHAT	Q02156	PRKCE	T574	A577T	577	Missense	distal	3	no	17.341	16.938	EPSD	COSMIC	13.948	Down-regulation
AGC_PKC_PKCh_PRKCE_ST	P28329	CHAT	Q02156	PRKCE	T574	V567M	567	Missense	distal	-7	no	17.341	17.862	EPSD	COSMIC;GDSC;CCLE	13.948	Up-regulation
AGC_PKC_PKCh_PRKCE_ST	P28329	CHAT	Q02156	PRKCE	T574	T574I	574	Missense	central	0	yes	17.341	0.000	EPSD	COSMIC	13.948	Loss
AGC_PKC_PKCh_PRKCE_ST	P28329	CHAT	Q02156	PRKCE	T574	V567A	567	Missense	distal	-7	no	17.341	17.490	EPSD	COSMIC	13.948	Up-regulation
AGC_PKC_PKCh_PRKCE_ST	P28329	CHAT	Q02156	PRKCE	T574	P575S	575	Missense	proximal	1	no	17.341	18.470	EPSD	COSMIC	13.948	Up-regulation
AGC_PKC_PKCh_PRKCE_ST	P28329	CHAT	Q02156	PRKCE	T574	R571K	571	Missense	distal	-3	no	17.341	17.358	EPSD	COSMIC	13.948	Up-regulation
AGC_PKC_PKCh_PRKCE_ST	P28329	CHAT	Q02156	PRKCE	S594	K588M	588	Missense	distal	-6	no	16.427	16.333	EPSD	COSMIC	13.948	Down-regulation
AGC_PKC_PKCh_PRKCE_ST	P28329	CHAT	Q02156	PRKCE	S594	L599F	599	Missense	distal	5	no	16.427	16.533	EPSD	COSMIC	13.948	Up-regulation
AGC_PKC_PKCh_PRKCE_ST	P28329	CHAT	Q02156	PRKCE	S594	E595K	595	Missense	proximal	1	no	16.427	19.114	EPSD	COSMIC	13.948	Up-regulation
AGC_PKC_PKCh_PRKCE_ST	P17302	GJA1	Q02156	PRKCE	S244	K243N	243	Missense	proximal	-1	no	15.603	15.369	EPSD	COSMIC	13.948	Down-regulation
AGC_PKC_PKCh_PRKCE_ST	P17302	GJA1	Q02156	PRKCE	S244	D245Y	245	Missense	proximal	1	no	15.603	17.514	EPSD	COSMIC	13.948	Up-regulation
AGC_PKC_PKCh_PRKCE_ST	P17302	GJA1	Q02156	PRKCE	S262	D259Y	259	Missense	distal	-3	no	13.473	14.046	EPSD	COSMIC	13.948	Gain
AGC_PKC_PKCh_PRKCE_ST	P17302	GJA1	Q02156	PRKCE	S296	R299L	299	Missense	distal	3	no	17.123	16.737	EPSD	COSMIC;GDSC;CCLE	13.948	Down-regulation
AGC_PKC_PKCh_PRKCE_ST	P17302	GJA1	Q02156	PRKCE	S296	N302S	302	Missense	distal	6	no	17.123	17.167	EPSD	COSMIC	13.948	Up-regulation
AGC_PKC_PKCh_PRKCE_ST	P17302	GJA1	Q02156	PRKCE	S364	P363L	363	Missense	proximal	-1	no	23.628	23.692	EPSD	COSMIC	13.948	Up-regulation
AGC_PKC_PKCh_PRKCE_ST	P17302	GJA1	Q02156	PRKCE	S364	R370S	370	Missense	distal	6	no	23.628	24.049	EPSD	COSMIC	13.948	Up-regulation
AGC_PKC_PKCh_PRKCE_ST	P17302	GJA1	Q02156	PRKCE	S365	P363L	363	Missense	proximal	-2	no	18.789	16.356	EPSD	COSMIC	13.948	Down-regulation
AGC_PKC_PKCh_PRKCE_ST	P17302	GJA1	Q02156	PRKCE	S365	R370S	370	Missense	distal	5	no	18.789	18.990	EPSD	COSMIC	13.948	Up-regulation
AGC_PKC_PKCh_PRKCE_ST	P17302	GJA1	Q02156	PRKCE	S368	P363L	363	Missense	distal	-5	no	25.616	25.611	PhosphoSitePlus	COSMIC	13.948	Down-regulation
AGC_PKC_PKCh_PRKCE_ST	P17302	GJA1	Q02156	PRKCE	S368	R370S	370	Missense	proximal	2	no	25.616	19.178	PhosphoSitePlus	COSMIC	13.948	Down-regulation
AGC_PKC_PKCh_PRKCE_ST	P17302	GJA1	Q02156	PRKCE	S369	P363L	363	Missense	distal	-6	no	20.672	20.652	EPSD	COSMIC	13.948	Down-regulation
AGC_PKC_PKCh_PRKCE_ST	P17302	GJA1	Q02156	PRKCE	S369	R370S	370	Missense	proximal	1	no	20.672	20.252	EPSD	COSMIC	13.948	Down-regulation
AGC_PKC_PKCh_PRKCE_ST	P17302	GJA1	Q02156	PRKCE	S372	R370S	370	Missense	proximal	-2	no	28.412	27.601	EPSD	COSMIC	13.948	Down-regulation
AGC_PKC_PKCh_PRKCE_ST	P17302	GJA1	Q02156	PRKCE	S373	R370S	370	Missense	distal	-3	no	21.819	17.050	EPSD	COSMIC	13.948	Down-regulation
AGC_PKC_PKCh_PRKCE_ST	Q9BZL6	PRKD2	Q02156	PRKCE	S206	S203I	203	Missense	distal	-3	no	13.572	14.144	EPSD	COSMIC	13.948	Gain
AGC_PKC_PKCh_PRKCE_ST	Q9BZL6	PRKD2	Q02156	PRKCE	S236	S237F	237	Missense	proximal	1	no	15.037	16.373	EPSD	COSMIC	13.948	Up-regulation
AGC_PKC_PKCh_PRKCE_ST	Q9BZL6	PRKD2	Q02156	PRKCE	S236	R232H	232	Missense	distal	-4	no	15.037	15.502	EPSD	COSMIC	13.948	Up-regulation
AGC_PKC_PKCh_PRKCE_ST	Q9BZL6	PRKD2	Q02156	PRKCE	S236	S239F	239	Missense	distal	3	no	15.037	15.002	EPSD	COSMIC	13.948	Down-regulation
AGC_PKC_PKCh_PRKCE_ST	Q9BZL6	PRKD2	Q02156	PRKCE	S236	S241Y	241	Missense	distal	5	no	15.037	15.054	EPSD	COSMIC	13.948	Up-regulation
AGC_PKC_PKCh_PRKCE_ST	Q9BZL6	PRKD2	Q02156	PRKCE	S236	R232L	232	Missense	distal	-4	no	15.037	15.268	EPSD	COSMIC	13.948	Up-regulation
AGC_PKC_PKCh_PRKCE_ST	Q9BZL6	PRKD2	Q02156	PRKCE	S239	S237F	237	Missense	proximal	-2	no	14.126	12.261	EPSD	COSMIC	13.948	Loss
AGC_PKC_PKCh_PRKCE_ST	Q9BZL6	PRKD2	Q02156	PRKCE	S239	R232H	232	Missense	distal	-7	no	14.126	13.662	EPSD	COSMIC	13.948	Loss
AGC_PKC_PKCh_PRKCE_ST	Q9BZL6	PRKD2	Q02156	PRKCE	S239	S239F	239	Missense	central	0	yes	14.126	0.000	EPSD	COSMIC	13.948	Loss
AGC_PKC_PKCh_PRKCE_ST	Q9BZL6	PRKD2	Q02156	PRKCE	S239	S241Y	241	Missense	proximal	2	no	14.126	13.881	EPSD	COSMIC	13.948	Loss
AGC_PKC_PKCh_PRKCE_ST	Q9BZL6	PRKD2	Q02156	PRKCE	S239	R232L	232	Missense	distal	-7	no	14.126	13.805	EPSD	COSMIC	13.948	Loss
AGC_PKC_PKCh_PRKCE_ST	Q9BZL6	PRKD2	Q02156	PRKCE	T392	T391M	391	Missense	proximal	-1	no	13.404	14.723	EPSD	COSMIC	13.948	Gain
AGC_PKC_PKCh_PRKCE_ST	Q9BZL6	PRKD2	Q02156	PRKCE	S529	A523T	523	Missense	distal	-6	no	14.764	14.689	EPSD	COSMIC;GDSC	13.948	Down-regulation
AGC_PKC_PKCh_PRKCE_ST	Q9BZL6	PRKD2	Q02156	PRKCE	S706	F707L	707	Missense	proximal	1	no	20.395	19.293	EPSD;PhosphoSitePlus	COSMIC	13.948	Down-regulation
AGC_PKC_PKCh_PRKCE_ST	Q9BZL6	PRKD2	Q02156	PRKCE	S706	A699V	699	Missense	distal	-7	no	20.395	20.245	EPSD;PhosphoSitePlus	COSMIC	13.948	Down-regulation
AGC_PKC_PKCh_PRKCE_ST	Q9BZL6	PRKD2	Q02156	PRKCE	S706	G703D	703	Missense	distal	-3	no	20.395	21.264	EPSD;PhosphoSitePlus	COSMIC	13.948	Up-regulation
AGC_PKC_PKCh_PRKCE_ST	Q9BZL6	PRKD2	Q02156	PRKCE	S706	R700H	700	Missense	distal	-6	no	20.395	20.218	EPSD;PhosphoSitePlus	COSMIC;CCLE	13.948	Down-regulation
AGC_PKC_PKCh_PRKCE_ST	Q9BZL6	PRKD2	Q02156	PRKCE	S706	G713R	713	Missense	distal	7	no	20.395	21.077	EPSD;PhosphoSitePlus	COSMIC	13.948	Up-regulation
AGC_PKC_PKCh_PRKCE_ST	Q9BZL6	PRKD2	Q02156	PRKCE	S706	G713E	713	Missense	distal	7	no	20.395	20.852	EPSD;PhosphoSitePlus	COSMIC	13.948	Up-regulation
AGC_PKC_PKCh_PRKCE_ST	Q9BZL6	PRKD2	Q02156	PRKCE	S710	F707L	707	Missense	distal	-3	no	17.665	15.806	EPSD;PhosphoSitePlus	COSMIC	13.948	Down-regulation
AGC_PKC_PKCh_PRKCE_ST	Q9BZL6	PRKD2	Q02156	PRKCE	S710	G703D	703	Missense	distal	-7	no	17.665	17.737	EPSD;PhosphoSitePlus	COSMIC	13.948	Up-regulation
AGC_PKC_PKCh_PRKCE_ST	Q9BZL6	PRKD2	Q02156	PRKCE	S710	G713R	713	Missense	distal	3	no	17.665	17.631	EPSD;PhosphoSitePlus	COSMIC	13.948	Down-regulation
AGC_PKC_PKCh_PRKCE_ST	Q9BZL6	PRKD2	Q02156	PRKCE	S710	G713E	713	Missense	distal	3	no	17.665	17.212	EPSD;PhosphoSitePlus	COSMIC	13.948	Down-regulation
AGC_PKC_PKCh_PRKCE_ST	Q9BZL6	PRKD2	Q02156	PRKCE	S876	G870E	870	Missense	distal	-6	no	15.012	14.995	PhosphoSitePlus;EPSD	COSMIC	13.948	Down-regulation
AGC_PKC_PKCh_PRKCE_ST	Q9BZL6	PRKD2	Q02156	PRKCE	S876	S876G	876	Missense	central	0	yes	15.012	0.000	PhosphoSitePlus;EPSD	COSMIC	13.948	Loss
AGC_PKC_PKCh_PRKCE_ST	Q9BZL6	PRKD2	Q02156	PRKCE	S876	G870R	870	Missense	distal	-6	no	15.012	15.111	PhosphoSitePlus;EPSD	COSMIC	13.948	Up-regulation
AGC_PKC_PKCh_PRKCE_ST	Q9BZL6	PRKD2	Q02156	PRKCE	S876	A872V	872	Missense	distal	-4	no	15.012	14.913	PhosphoSitePlus;EPSD	COSMIC	13.948	Down-regulation
AGC_PKC_PKCh_PRKCE_ST	P40763	STAT3	Q02156	PRKCE	S25	M28I	28	Missense	distal	3	no	14.117	13.797	EPSD	COSMIC	13.948	Loss
AGC_PKC_PKCh_PRKCE_ST	P40763	STAT3	Q02156	PRKCE	S25	L18V	18	Missense	distal	-7	no	14.117	14.055	EPSD	COSMIC	13.948	Down-regulation
AGC_PKC_PKCh_PRKCE_ST	P40763	STAT3	Q02156	PRKCE	S25	P27S	27	Missense	proximal	2	no	14.117	13.463	EPSD	COSMIC	13.948	Loss
AGC_PKC_PKCh_PRKCE_ST	P40763	STAT3	Q02156	PRKCE	S25	L18H	18	Missense	distal	-7	no	14.117	13.974	EPSD	COSMIC	13.948	Down-regulation
AGC_PKC_PKCh_PRKCE_ST	P40763	STAT3	Q02156	PRKCE	S25	L18P	18	Missense	distal	-7	no	14.117	14.141	EPSD	COSMIC	13.948	Up-regulation
AGC_PKC_PKCh_PRKCE_ST	P40763	STAT3	Q02156	PRKCE	T412	H410Q	410	Missense	proximal	-2	no	16.928	18.507	EPSD	COSMIC	13.948	Up-regulation
AGC_PKC_PKCh_PRKCE_ST	P40763	STAT3	Q02156	PRKCE	T412	L413M	413	Missense	proximal	1	no	16.928	16.884	EPSD	COSMIC	13.948	Down-regulation
AGC_PKC_PKCh_PRKCE_ST	P40763	STAT3	Q02156	PRKCE	T412	G419W	419	Missense	distal	7	no	16.928	15.115	EPSD	COSMIC	13.948	Down-regulation
AGC_PKC_PKCh_PRKCE_ST	P40763	STAT3	Q02156	PRKCE	T412	L413R	413	Missense	proximal	1	no	16.928	17.113	EPSD	COSMIC	13.948	Up-regulation
AGC_PKC_PKCh_PRKCE_ST	P40763	STAT3	Q02156	PRKCE	T412	L413P	413	Missense	proximal	1	no	16.928	15.565	EPSD	COSMIC	13.948	Down-regulation
AGC_PKC_PKCh_PRKCE_ST	P40763	STAT3	Q02156	PRKCE	T412	F408L	408	Missense	distal	-4	no	16.928	16.991	EPSD	COSMIC	13.948	Up-regulation
AGC_PKC_PKCh_PRKCE_ST	P40763	STAT3	Q02156	PRKCE	S691	D698N	698	Missense	distal	7	no	14.277	13.596	EPSD	COSMIC	13.948	Loss
AGC_PKC_PKCh_PRKCE_ST	P40763	STAT3	Q02156	PRKCE	S691	G684R	684	Missense	distal	-7	no	14.277	14.495	EPSD	COSMIC	13.948	Up-regulation
AGC_PKC_PKCh_PRKCE_ST	P40763	STAT3	Q02156	PRKCE	S727	D723N	723	Missense	distal	-4	no	18.269	18.441	PhosphoSitePlus	COSMIC	13.948	Up-regulation
AGC_PKC_PKCh_PRKCE_ST	O14920	IKBKB	Q02156	PRKCE	S177	E172G	172	Missense	distal	-5	no	16.356	16.361	PhosphoSitePlus	COSMIC	13.948	Up-regulation
AGC_PKC_PKCh_PRKCE_ST	O14920	IKBKB	Q02156	PRKCE	S177	K171E	171	Missense	distal	-6	no	16.356	16.279	PhosphoSitePlus	COSMIC;CCLE	13.948	Down-regulation
AGC_PKC_PKCh_PRKCE_ST	O14920	IKBKB	Q02156	PRKCE	S177	A170T	170	Missense	distal	-7	no	16.356	16.180	PhosphoSitePlus	COSMIC	13.948	Down-regulation
AGC_PKC_PKCh_PRKCE_ST	O14920	IKBKB	Q02156	PRKCE	S177	K171T	171	Missense	distal	-6	no	16.356	16.181	PhosphoSitePlus	COSMIC	13.948	Down-regulation
AGC_PKC_PKCh_PRKCE_ST	O14920	IKBKB	Q02156	PRKCE	S177	K171M	171	Missense	distal	-6	no	16.356	16.262	PhosphoSitePlus	COSMIC	13.948	Down-regulation
AGC_PKC_PKCh_PRKCE_ST	O14920	IKBKB	Q02156	PRKCE	S177	K171Q	171	Missense	distal	-6	no	16.356	16.291	PhosphoSitePlus	COSMIC	13.948	Down-regulation
AGC_PKC_PKCh_PRKCE_ST	O14920	IKBKB	Q02156	PRKCE	S257	G251E	251	Missense	distal	-6	no	14.353	14.336	EPSD	COSMIC	13.948	Down-regulation
AGC_PKC_PKCh_PRKCE_ST	O14920	IKBKB	Q02156	PRKCE	S257	F255V	255	Missense	proximal	-2	no	14.353	15.466	EPSD	COSMIC	13.948	Up-regulation
AGC_PKC_PKCh_PRKCE_ST	O14920	IKBKB	Q02156	PRKCE	S257	S258Y	258	Missense	proximal	1	no	14.353	16.372	EPSD	COSMIC	13.948	Up-regulation
AGC_PKC_PKCh_PRKCE_ST	O14920	IKBKB	Q02156	PRKCE	S257	N264K	264	Missense	distal	7	no	14.353	15.201	EPSD	COSMIC	13.948	Up-regulation
AGC_PKC_PKCh_PRKCE_ST	O14920	IKBKB	Q02156	PRKCE	S257	N264H	264	Missense	distal	7	no	14.353	13.779	EPSD	COSMIC	13.948	Loss
AGC_PKC_PKCh_PRKCE_ST	O14920	IKBKB	Q02156	PRKCE	S257	S256Y	256	Missense	proximal	-1	no	14.353	14.869	EPSD	COSMIC	13.948	Up-regulation
AGC_PKC_PKCh_PRKCE_ST	O14920	IKBKB	Q02156	PRKCE	T368	G374R	374	Missense	distal	6	no	15.594	15.251	EPSD	COSMIC	13.948	Down-regulation
AGC_PKC_PKCh_PRKCE_ST	O14920	IKBKB	Q02156	PRKCE	T368	P363H	363	Missense	distal	-5	no	15.594	15.613	EPSD	COSMIC	13.948	Up-regulation
AGC_PKC_PKCh_PRKCE_ST	O14920	IKBKB	Q02156	PRKCE	T368	G374S	374	Missense	distal	6	no	15.594	15.672	EPSD	COSMIC;GDSC;CCLE	13.948	Up-regulation
AGC_PKC_PKCh_PRKCE_ST	O14920	IKBKB	Q02156	PRKCE	T368	K375T	375	Missense	distal	7	no	15.594	14.791	EPSD	COSMIC	13.948	Down-regulation
AGC_PKC_PKCh_PRKCE_ST	O14920	IKBKB	Q02156	PRKCE	S402	R404Q	404	Missense	proximal	2	no	14.109	8.877	EPSD	COSMIC;CCLE	13.948	Loss
AGC_PKC_PKCh_PRKCE_ST	O14920	IKBKB	Q02156	PRKCE	S402	S402F	402	Missense	central	0	yes	14.109	0.000	EPSD	COSMIC	13.948	Loss
AGC_PKC_PKCh_PRKCE_ST	O14920	IKBKB	Q02156	PRKCE	S402	R404L	404	Missense	proximal	2	no	14.109	6.474	EPSD	COSMIC	13.948	Loss
AGC_PKC_PKCh_PRKCE_ST	O14920	IKBKB	Q02156	PRKCE	S507	T501P	501	Missense	distal	-6	no	14.810	14.896	EPSD	COSMIC	13.948	Up-regulation
AGC_PKC_PKCh_PRKCE_ST	O14920	IKBKB	Q02156	PRKCE	S507	F503C	503	Missense	distal	-4	no	14.810	14.957	EPSD	COSMIC	13.948	Up-regulation
AGC_PKC_PKCh_PRKCE_ST	O14920	IKBKB	Q02156	PRKCE	S507	A513G	513	Missense	distal	6	no	14.810	14.922	EPSD	COSMIC	13.948	Up-regulation
AGC_PKC_PKCh_PRKCE_ST	O14920	IKBKB	Q02156	PRKCE	S587	E589D	589	Missense	proximal	2	no	13.588	14.203	EPSD	COSMIC	13.948	Gain
AGC_PKC_PKCh_PRKCE_ST	O14920	IKBKB	Q02156	PRKCE	S587	R592W	592	Missense	distal	5	no	13.588	14.357	EPSD	COSMIC	13.948	Gain
AGC_PKC_PKCh_PRKCE_ST	O14920	IKBKB	Q02156	PRKCE	S600	I598S	598	Missense	proximal	-2	no	12.366	14.007	EPSD	COSMIC	13.948	Gain
AGC_PKC_PKCh_PRKCE_ST	O14920	IKBKB	Q02156	PRKCE	S756	H749N	749	Missense	distal	-7	no	14.378	14.597	EPSD	COSMIC	13.948	Up-regulation
AGC_PKC_PKCh_PRKCE_ST	P19429	TNNI3	Q02156	PRKCE	S23	R27H	27	Missense	distal	4	no	20.306	17.487	EPSD	COSMIC	13.948	Down-regulation
AGC_PKC_PKCh_PRKCE_ST	P19429	TNNI3	Q02156	PRKCE	S23	S23P	23	Missense	central	0	yes	20.306	0.000	EPSD	COSMIC	13.948	Loss
AGC_PKC_PKCh_PRKCE_ST	P19429	TNNI3	Q02156	PRKCE	S24	R27H	27	Missense	distal	3	no	17.186	16.273	EPSD	COSMIC	13.948	Down-regulation
AGC_PKC_PKCh_PRKCE_ST	P19429	TNNI3	Q02156	PRKCE	S24	S23P	23	Missense	proximal	-1	no	17.186	16.747	EPSD	COSMIC	13.948	Down-regulation
AGC_PKC_PKCh_PRKCE_ST	P19429	TNNI3	Q02156	PRKCE	S44	K37T	37	Missense	distal	-7	no	16.546	16.357	PhosphoSitePlus	COSMIC	13.948	Down-regulation
AGC_PKC_PKCh_PRKCE_ST	P19429	TNNI3	Q02156	PRKCE	S77	Q81H	81	Missense	distal	4	no	23.315	21.027	EPSD	COSMIC	13.948	Down-regulation
AGC_PKC_PKCh_PRKCE_ST	P19429	TNNI3	Q02156	PRKCE	S77	A75S	75	Missense	proximal	-2	no	23.315	24.232	EPSD	COSMIC	13.948	Up-regulation
AGC_PKC_PKCh_PRKCE_ST	P19429	TNNI3	Q02156	PRKCE	S77	G73W	73	Missense	distal	-4	no	23.315	23.554	EPSD	COSMIC	13.948	Up-regulation
AGC_PKC_PKCh_PRKCE_ST	P19429	TNNI3	Q02156	PRKCE	S77	P82S	82	Missense	distal	5	no	23.315	23.207	EPSD	COSMIC	13.948	Down-regulation
AGC_PKC_PKCh_PRKCE_ST	P19429	TNNI3	Q02156	PRKCE	T143	R141Q	141	Missense	proximal	-2	no	19.722	18.751	EPSD	COSMIC	13.948	Down-regulation
AGC_PKC_PKCh_PRKCE_ST	P19429	TNNI3	Q02156	PRKCE	T143	R146I	146	Missense	distal	3	no	19.722	19.370	EPSD	COSMIC	13.948	Down-regulation
AGC_PKC_PKCh_PRKCE_ST	P19429	TNNI3	Q02156	PRKCE	T181	E187G	187	Missense	distal	6	no	19.745	19.959	EPSD	COSMIC	13.948	Up-regulation
AGC_PKC_PKCh_PRKCE_ST	P19429	TNNI3	Q02156	PRKCE	T181	V176G	176	Missense	distal	-5	no	19.745	19.755	EPSD	COSMIC	13.948	Up-regulation
AGC_PKC_PKCh_PRKCE_ST	P15336	ATF2	Q02156	PRKCE	T52	K48R	48	Missense	distal	-4	no	15.936	15.664	PhosphoSitePlus	COSMIC	13.948	Down-regulation
AGC_PKC_PKCh_PRKCE_ST	P15336	ATF2	Q02156	PRKCE	T52	M51I	51	Missense	proximal	-1	no	15.936	14.367	PhosphoSitePlus	COSMIC	13.948	Down-regulation
AGC_PKC_PKCh_PRKCE_ST	P15336	ATF2	Q02156	PRKCE	T52	H45N	45	Missense	distal	-7	no	15.936	16.155	PhosphoSitePlus	COSMIC	13.948	Up-regulation
AGC_PKC_PKCh_PRKCE_ST	P15336	ATF2	Q02156	PRKCE	T52	R59C	59	Missense	distal	7	no	15.936	15.516	PhosphoSitePlus	COSMIC	13.948	Down-regulation
AGC_PKC_PKCh_PRKCE_ST	P15336	ATF2	Q02156	PRKCE	T52	G56V	56	Missense	distal	4	no	15.936	15.417	PhosphoSitePlus	COSMIC	13.948	Down-regulation
AGC_PKC_PKCh_PRKCE_ST	P15336	ATF2	Q02156	PRKCE	S100	M107I	107	Missense	distal	7	no	23.109	22.538	EPSD	COSMIC;GDSC;CCLE	13.948	Down-regulation
AGC_PKC_PKCh_PRKCE_ST	P15336	ATF2	Q02156	PRKCE	S100	K105T	105	Missense	distal	5	no	23.109	23.376	EPSD	COSMIC;GDSC;CCLE	13.948	Up-regulation
AGC_PKC_PKCh_PRKCE_ST	P15336	ATF2	Q02156	PRKCE	S100	K106R	106	Missense	distal	6	no	23.109	22.686	EPSD	COSMIC	13.948	Down-regulation
AGC_PKC_PKCh_PRKCE_ST	P15336	ATF2	Q02156	PRKCE	S121	E125K	125	Missense	distal	4	no	13.402	14.981	EPSD	COSMIC	13.948	Gain
AGC_PKC_PKCh_PRKCE_ST	P15336	ATF2	Q02156	PRKCE	T253	V258I	258	Missense	distal	5	no	15.685	15.842	EPSD	COSMIC;GDSC;CCLE	13.948	Up-regulation
AGC_PKC_PKCh_PRKCE_ST	P15336	ATF2	Q02156	PRKCE	T253	V258F	258	Missense	distal	5	no	15.685	15.739	EPSD	COSMIC	13.948	Up-regulation
AGC_PKC_PKCh_PRKCE_ST	P15336	ATF2	Q02156	PRKCE	T253	S257R	257	Missense	distal	4	no	15.685	16.065	EPSD	COSMIC	13.948	Up-regulation
AGC_PKC_PKCh_PRKCE_ST	P15336	ATF2	Q02156	PRKCE	T253	P251Q	251	Missense	proximal	-2	no	15.685	15.385	EPSD	COSMIC	13.948	Down-regulation
AGC_PKC_PKCh_PRKCE_ST	P15336	ATF2	Q02156	PRKCE	S340	Q337K	337	Missense	distal	-3	no	17.489	23.072	EPSD	COSMIC	13.948	Up-regulation
AGC_PKC_PKCh_PRKCE_ST	P15336	ATF2	Q02156	PRKCE	S340	Q335H	335	Missense	distal	-5	no	17.489	17.514	EPSD	COSMIC	13.948	Up-regulation
AGC_PKC_PKCh_PRKCE_ST	P15336	ATF2	Q02156	PRKCE	S340	R343L	343	Missense	distal	3	no	17.489	17.103	EPSD	COSMIC	13.948	Down-regulation
AGC_PKC_PKCh_PRKCE_ST	P15336	ATF2	Q02156	PRKCE	S340	P334S	334	Missense	distal	-6	no	17.489	17.499	EPSD	COSMIC	13.948	Up-regulation
AGC_PKC_PKCh_PRKCE_ST	P15336	ATF2	Q02156	PRKCE	S340	R345T	345	Missense	distal	5	no	17.489	18.007	EPSD	COSMIC	13.948	Up-regulation
AGC_PKC_PKCh_PRKCE_ST	P15336	ATF2	Q02156	PRKCE	S340	R343Q	343	Missense	distal	3	no	17.489	17.323	EPSD	COSMIC	13.948	Down-regulation
AGC_PKC_PKCh_PRKCE_ST	P15336	ATF2	Q02156	PRKCE	S340	A347T	347	Missense	distal	7	no	17.489	16.651	EPSD	COSMIC	13.948	Down-regulation
AGC_PKC_PKCh_PRKCE_ST	P15336	ATF2	Q02156	PRKCE	S340	R345K	345	Missense	distal	5	no	17.489	17.740	EPSD	COSMIC	13.948	Up-regulation
AGC_PKC_PKCh_PRKCE_ST	P15336	ATF2	Q02156	PRKCE	S484	Q479P	479	Missense	distal	-5	no	14.382	14.388	EPSD	COSMIC	13.948	Up-regulation
AGC_PKC_PKCh_PRKCE_ST	P15336	ATF2	Q02156	PRKCE	S484	Q483K	483	Missense	proximal	-1	no	14.382	14.423	EPSD	COSMIC	13.948	Up-regulation
AGC_PKC_PKCh_PRKCE_ST	P15336	ATF2	Q02156	PRKCE	S490	V493I	493	Missense	distal	3	no	14.467	13.947	EPSD	COSMIC	13.948	Loss
AGC_PKC_PKCh_PRKCE_ST	P15336	ATF2	Q02156	PRKCE	S490	Q483K	483	Missense	distal	-7	no	14.467	14.428	EPSD	COSMIC	13.948	Down-regulation
AGC_PKC_PKCh_PRKCE_ST	P15336	ATF2	Q02156	PRKCE	S498	V493I	493	Missense	distal	-5	no	18.193	18.226	EPSD	COSMIC	13.948	Up-regulation
AGC_PKC_PKCh_PRKCE_ST	P15336	ATF2	Q02156	PRKCE	S498	Q501K	501	Missense	distal	3	no	18.193	18.567	EPSD	COSMIC	13.948	Up-regulation
AGC_PKC_PKCh_PRKCE_ST	P15336	ATF2	Q02156	PRKCE	S500	V493I	493	Missense	distal	-7	no	18.357	18.388	EPSD	COSMIC	13.948	Up-regulation
AGC_PKC_PKCh_PRKCE_ST	P15336	ATF2	Q02156	PRKCE	S500	Q501K	501	Missense	proximal	1	no	18.357	20.582	EPSD	COSMIC	13.948	Up-regulation
AGC_PKC_PKCh_PRKCE_ST	Q16612	NREP	Q02156	PRKCE	S59	S59F	59	Missense	central	0	yes	17.731	0.000	PhosphoSitePlus	COSMIC	13.948	Loss
AGC_PKC_PKCh_PRKCE_ST	Q16612	NREP	Q02156	PRKCE	S59	H66Y	66	Missense	distal	7	no	17.731	18.920	PhosphoSitePlus	COSMIC	13.948	Up-regulation
AGC_PKC_PKCh_PRKCE_ST	Q16612	NREP	Q02156	PRKCE	S59	P60T	60	Missense	proximal	1	no	17.731	18.313	PhosphoSitePlus	COSMIC	13.948	Up-regulation
AGC_PKC_PKCh_PRKCE_ST	Q16612	NREP	Q02156	PRKCE	S59	L65R	65	Missense	distal	6	no	17.731	17.293	PhosphoSitePlus	COSMIC	13.948	Down-regulation
AGC_PKC_PKCh_PRKCE_ST	O60716	CTNND1	Q02156	PRKCE	T61	G58D	58	Missense	distal	-3	no	13.143	14.012	EPSD	COSMIC	13.948	Gain
AGC_PKC_PKCh_PRKCE_ST	O60716	CTNND1	Q02156	PRKCE	T149	T152P	152	Missense	distal	3	no	14.978	15.501	EPSD	COSMIC	13.948	Up-regulation
AGC_PKC_PKCh_PRKCE_ST	O60716	CTNND1	Q02156	PRKCE	T149	T152S	152	Missense	distal	3	no	14.978	15.441	EPSD	COSMIC	13.948	Up-regulation
AGC_PKC_PKCh_PRKCE_ST	O60716	CTNND1	Q02156	PRKCE	T149	T147I	147	Missense	proximal	-2	no	14.978	14.846	EPSD	COSMIC	13.948	Down-regulation
AGC_PKC_PKCh_PRKCE_ST	O60716	CTNND1	Q02156	PRKCE	S225	P222S	222	Missense	distal	-3	no	11.927	15.244	EPSD	COSMIC	13.948	Gain
AGC_PKC_PKCh_PRKCE_ST	O60716	CTNND1	Q02156	PRKCE	S252	P251H	251	Missense	proximal	-1	no	15.323	14.794	EPSD	COSMIC	13.948	Down-regulation
AGC_PKC_PKCh_PRKCE_ST	O60716	CTNND1	Q02156	PRKCE	S252	G258R	258	Missense	distal	6	no	15.323	14.980	EPSD	COSMIC	13.948	Down-regulation
AGC_PKC_PKCh_PRKCE_ST	O60716	CTNND1	Q02156	PRKCE	S252	R253I	253	Missense	proximal	1	no	15.323	15.660	EPSD	COSMIC	13.948	Up-regulation
AGC_PKC_PKCh_PRKCE_ST	O60716	CTNND1	Q02156	PRKCE	S252	M245L	245	Missense	distal	-7	no	15.323	14.863	EPSD	COSMIC	13.948	Down-regulation
AGC_PKC_PKCh_PRKCE_ST	O60716	CTNND1	Q02156	PRKCE	S268	H273Y	273	Missense	distal	5	no	15.243	15.097	PhosphoSitePlus	COSMIC	13.948	Down-regulation
AGC_PKC_PKCh_PRKCE_ST	O60716	CTNND1	Q02156	PRKCE	S268	V270M	270	Missense	proximal	2	no	15.243	6.445	PhosphoSitePlus	COSMIC	13.948	Loss
AGC_PKC_PKCh_PRKCE_ST	O60716	CTNND1	Q02156	PRKCE	S268	S269G	269	Missense	proximal	1	no	15.243	15.861	PhosphoSitePlus	COSMIC	13.948	Up-regulation
AGC_PKC_PKCh_PRKCE_ST	O60716	CTNND1	Q02156	PRKCE	S268	S268N	268	Missense	central	0	yes	15.243	0.000	PhosphoSitePlus	COSMIC	13.948	Loss
AGC_PKC_PKCh_PRKCE_ST	O60716	CTNND1	Q02156	PRKCE	S320	R316W	316	Missense	distal	-4	no	15.343	15.895	EPSD	COSMIC	13.948	Up-regulation
AGC_PKC_PKCh_PRKCE_ST	O60716	CTNND1	Q02156	PRKCE	S320	R316L	316	Missense	distal	-4	no	15.343	15.573	EPSD	COSMIC	13.948	Up-regulation
AGC_PKC_PKCh_PRKCE_ST	O60716	CTNND1	Q02156	PRKCE	S320	I325M	325	Missense	distal	5	no	15.343	15.181	EPSD	COSMIC	13.948	Down-regulation
AGC_PKC_PKCh_PRKCE_ST	O60716	CTNND1	Q02156	PRKCE	S320	G326C	326	Missense	distal	6	no	15.343	15.386	EPSD	COSMIC	13.948	Up-regulation
AGC_PKC_PKCh_PRKCE_ST	O60716	CTNND1	Q02156	PRKCE	S484	M487V	487	Missense	distal	3	no	18.581	18.781	EPSD	COSMIC	13.948	Up-regulation
AGC_PKC_PKCh_PRKCE_ST	O60716	CTNND1	Q02156	PRKCE	S484	D483N	483	Missense	proximal	-1	no	18.581	18.665	EPSD	COSMIC	13.948	Up-regulation
AGC_PKC_PKCh_PRKCE_ST	O60716	CTNND1	Q02156	PRKCE	S484	S484L	484	Missense	central	0	yes	18.581	0.000	EPSD	COSMIC	13.948	Loss
AGC_PKC_PKCh_PRKCE_ST	O60716	CTNND1	Q02156	PRKCE	S484	V490A	490	Missense	distal	6	no	18.581	18.267	EPSD	COSMIC	13.948	Down-regulation
AGC_PKC_PKCh_PRKCE_ST	O60716	CTNND1	Q02156	PRKCE	S587	H591Y	591	Missense	distal	4	no	13.384	14.498	EPSD	COSMIC	13.948	Gain
AGC_PKC_PKCh_PRKCE_ST	O60716	CTNND1	Q02156	PRKCE	S731	R725W	725	Missense	distal	-6	no	16.625	16.334	EPSD	COSMIC	13.948	Down-regulation
AGC_PKC_PKCh_PRKCE_ST	O60716	CTNND1	Q02156	PRKCE	S731	R725Q	725	Missense	distal	-6	no	16.625	16.520	EPSD	COSMIC	13.948	Down-regulation
AGC_PKC_PKCh_PRKCE_ST	O60716	CTNND1	Q02156	PRKCE	S731	A733T	733	Missense	proximal	2	no	16.625	13.824	EPSD	COSMIC	13.948	Loss
AGC_PKC_PKCh_PRKCE_ST	O60716	CTNND1	Q02156	PRKCE	S731	A733V	733	Missense	proximal	2	no	16.625	19.043	EPSD	COSMIC	13.948	Up-regulation
AGC_PKC_PKCh_PRKCE_ST	O60716	CTNND1	Q02156	PRKCE	S811	R814C	814	Missense	distal	3	no	17.985	17.578	EPSD	COSMIC	13.948	Down-regulation
AGC_PKC_PKCh_PRKCE_ST	O60716	CTNND1	Q02156	PRKCE	S811	R814L	814	Missense	distal	3	no	17.985	17.600	EPSD	COSMIC	13.948	Down-regulation
AGC_PKC_PKCh_PRKCE_ST	P08581	MET	Q02156	PRKCE	S283	S290F	290	Missense	distal	7	no	16.406	16.746	EPSD	COSMIC	13.948	Up-regulation
AGC_PKC_PKCh_PRKCE_ST	P08581	MET	Q02156	PRKCE	S283	R277T	277	Missense	distal	-6	no	16.406	16.192	EPSD	COSMIC	13.948	Down-regulation
AGC_PKC_PKCh_PRKCE_ST	P08581	MET	Q02156	PRKCE	S283	I284M	284	Missense	proximal	1	no	16.406	15.840	EPSD	COSMIC	13.948	Down-regulation
AGC_PKC_PKCh_PRKCE_ST	P08581	MET	Q02156	PRKCE	S283	N285S	285	Missense	proximal	2	no	16.406	15.742	EPSD	COSMIC	13.948	Down-regulation
AGC_PKC_PKCh_PRKCE_ST	P08581	MET	Q02156	PRKCE	S283	F281L	281	Missense	proximal	-2	no	16.406	15.978	EPSD	COSMIC	13.948	Down-regulation
AGC_PKC_PKCh_PRKCE_ST	P08581	MET	Q02156	PRKCE	S985	T992I	992	Missense	distal	7	no	20.739	20.491	PhosphoSitePlus	COSMIC	13.948	Down-regulation
AGC_PKC_PKCh_PRKCE_ST	P08581	MET	Q02156	PRKCE	S985	V984A	984	Missense	proximal	-1	no	20.739	20.936	PhosphoSitePlus	COSMIC	13.948	Up-regulation
AGC_PKC_PKCh_PRKCE_ST	P08581	MET	Q02156	PRKCE	S985	A986D	986	Missense	proximal	1	no	20.739	21.546	PhosphoSitePlus	COSMIC	13.948	Up-regulation
AGC_PKC_PKCh_PRKCE_ST	P08581	MET	Q02156	PRKCE	S985	R987Q	987	Missense	proximal	2	no	20.739	15.507	PhosphoSitePlus	COSMIC	13.948	Down-regulation
AGC_PKC_PKCh_PRKCE_ST	P08581	MET	Q02156	PRKCE	S985	L980V	980	Missense	distal	-5	no	20.739	20.731	PhosphoSitePlus	COSMIC	13.948	Down-regulation
AGC_PKC_PKCh_PRKCE_ST	P08581	MET	Q02156	PRKCE	S985	P991S	991	Missense	distal	6	no	20.739	20.634	PhosphoSitePlus	COSMIC	13.948	Down-regulation
AGC_PKC_PKCh_PRKCE_ST	P08581	MET	Q02156	PRKCE	S985	P978S	978	Missense	distal	-7	no	20.739	20.865	PhosphoSitePlus	COSMIC	13.948	Up-regulation
AGC_PKC_PKCh_PRKCE_ST	P08581	MET	Q02156	PRKCE	T1241	H1238R	1238	Missense	distal	-3	no	11.968	17.187	EPSD	COSMIC	13.948	Gain
AGC_PKC_PKCh_PRKCE_ST	P08581	MET	Q02156	PRKCE	T1257	L1255M	1255	Missense	proximal	-2	no	12.165	15.032	EPSD	COSMIC	13.948	Gain
AGC_PKC_PKCh_PRKCE_ST	P08581	MET	Q02156	PRKCE	T1261	T1261I	1261	Missense	central	0	yes	15.563	0.000	EPSD	COSMIC	13.948	Loss
AGC_PKC_PKCh_PRKCE_ST	P08581	MET	Q02156	PRKCE	T1261	L1255M	1255	Missense	distal	-6	no	15.563	15.577	EPSD	COSMIC	13.948	Up-regulation
AGC_PKC_PKCh_PRKCE_ST	P08581	MET	Q02156	PRKCE	T1261	V1266M	1266	Missense	distal	5	no	15.563	15.559	EPSD	COSMIC	13.948	Down-regulation
AGC_PKC_PKCh_PRKCE_ST	P08581	MET	Q02156	PRKCE	T1261	V1266A	1266	Missense	distal	5	no	15.563	15.787	EPSD	COSMIC	13.948	Up-regulation
AGC_PKC_PKCh_PRKCE_ST	P08581	MET	Q02156	PRKCE	T1262	L1255M	1255	Missense	distal	-7	no	13.501	13.961	EPSD	COSMIC	13.948	Gain
STE_STE20_MST_STK3_ST	P17252	PRKCA	Q13188	STK3	T108	G110E	110	Missense	proximal	2	no	59.282	58.651	EPSD	COSMIC	55.172	Down-regulation
STE_STE20_MST_STK3_ST	P17252	PRKCA	Q13188	STK3	T176	H174Y	174	Missense	proximal	-2	no	60.683	60.764	EPSD	COSMIC	55.172	Up-regulation
STE_STE20_MST_STK3_ST	P17252	PRKCA	Q13188	STK3	S226	K232T	232	Missense	distal	6	no	93.402	85.846	PhosphoSitePlus;EPSD	COSMIC	55.172	Down-regulation
STE_STE20_MST_STK3_ST	P17252	PRKCA	Q13188	STK3	T228	K232T	232	Missense	distal	4	no	111.878	111.550	EPSD;PhosphoSitePlus	COSMIC	55.172	Down-regulation
STE_STE20_MST_STK3_ST	P17252	PRKCA	Q13188	STK3	T497	T494M	494	Missense	distal	-3	no	70.838	69.621	EPSD	COSMIC	55.172	Down-regulation
STE_STE20_MST_STK3_ST	P17252	PRKCA	Q13188	STK3	T497	R496W	496	Missense	proximal	-1	no	70.838	72.218	EPSD	COSMIC	55.172	Up-regulation
STE_STE20_MST_STK3_ST	P00519	ABL1	Q13188	STK3	S157	P158L	158	Missense	proximal	1	no	40.778	59.212	EPSD	COSMIC	55.172	Gain
STE_STE20_MST_STK3_ST	P00519	ABL1	Q13188	STK3	T243	G250E	250	Missense	distal	7	no	65.816	65.639	EPSD	COSMIC	55.172	Down-regulation
STE_STE20_MST_STK3_ST	P00519	ABL1	Q13188	STK3	T243	M244V	244	Missense	proximal	1	no	65.816	64.698	EPSD	COSMIC	55.172	Down-regulation
STE_STE20_MST_STK3_ST	P00519	ABL1	Q13188	STK3	T243	L248V	248	Missense	distal	5	no	65.816	65.364	EPSD	COSMIC	55.172	Down-regulation
STE_STE20_MST_STK3_ST	P00519	ABL1	Q13188	STK3	T243	K247E	247	Missense	distal	4	no	65.816	64.439	EPSD	COSMIC	55.172	Down-regulation
STE_STE20_MST_STK3_ST	P00519	ABL1	Q13188	STK3	T243	T243I	243	Missense	central	0	yes	65.816	0.000	EPSD	COSMIC;GDSC	55.172	Loss
STE_STE20_MST_STK3_ST	P00519	ABL1	Q13188	STK3	T243	K247R	247	Missense	distal	4	no	65.816	65.624	EPSD	COSMIC	55.172	Down-regulation
STE_STE20_MST_STK3_ST	P00519	ABL1	Q13188	STK3	T243	I242M	242	Missense	proximal	-1	no	65.816	64.186	EPSD	COSMIC	55.172	Down-regulation
STE_STE20_MST_STK3_ST	P00519	ABL1	Q13188	STK3	T243	M237I	237	Missense	distal	-6	no	65.816	63.583	EPSD	COSMIC	55.172	Down-regulation
STE_STE20_MST_STK3_ST	P00519	ABL1	Q13188	STK3	T243	H246D	246	Missense	distal	3	no	65.816	63.245	EPSD	COSMIC	55.172	Down-regulation
STE_STE20_MST_STK3_ST	P00519	ABL1	Q13188	STK3	T243	E238K	238	Missense	distal	-5	no	65.816	62.462	EPSD	COSMIC	55.172	Down-regulation
STE_STE20_MST_STK3_ST	P00519	ABL1	Q13188	STK3	T243	H246R	246	Missense	distal	3	no	65.816	64.443	EPSD	COSMIC	55.172	Down-regulation
STE_STE20_MST_STK3_ST	P00519	ABL1	Q13188	STK3	T243	L248R	248	Missense	distal	5	no	65.816	65.743	EPSD	COSMIC	55.172	Down-regulation
STE_STE20_MST_STK3_ST	P00519	ABL1	Q13188	STK3	T532	A539V	539	Missense	distal	7	no	58.019	57.305	EPSD	COSMIC	55.172	Down-regulation
STE_STE20_MST_STK3_ST	P00519	ABL1	Q13188	STK3	T532	T530N	530	Missense	proximal	-2	no	58.019	57.688	EPSD	COSMIC	55.172	Down-regulation
STE_STE20_MST_STK3_ST	P00519	ABL1	Q13188	STK3	T532	P526S	526	Missense	distal	-6	no	58.019	60.590	EPSD	COSMIC	55.172	Up-regulation
STE_STE20_MST_STK3_ST	P00519	ABL1	Q13188	STK3	S535	T530N	530	Missense	distal	-5	no	53.423	58.129	EPSD	COSMIC	55.172	Gain
STE_STE20_MST_STK3_ST	P00519	ABL1	Q13188	STK3	S709	G706V	706	Missense	distal	-3	no	54.389	57.805	EPSD	COSMIC	55.172	Gain
STE_STE20_MST_STK3_ST	P00519	ABL1	Q13188	STK3	T735	T729M	729	Missense	distal	-6	no	96.619	95.305	PhosphoSitePlus	COSMIC	55.172	Down-regulation
STE_STE20_MST_STK3_ST	P00519	ABL1	Q13188	STK3	T735	R732G	732	Missense	distal	-3	no	96.619	91.471	PhosphoSitePlus	COSMIC	55.172	Down-regulation
STE_STE20_MST_STK3_ST	P00519	ABL1	Q13188	STK3	T735	R732S	732	Missense	distal	-3	no	96.619	98.457	PhosphoSitePlus	COSMIC	55.172	Up-regulation
STE_STE20_MST_STK3_ST	P00519	ABL1	Q13188	STK3	T735	R738Q	738	Missense	distal	3	no	96.619	95.481	PhosphoSitePlus	COSMIC	55.172	Down-regulation
STE_STE20_MST_STK3_ST	P00519	ABL1	Q13188	STK3	T735	R738W	738	Missense	distal	3	no	96.619	98.453	PhosphoSitePlus	COSMIC	55.172	Up-regulation
STE_STE20_MST_STK3_ST	P00519	ABL1	Q13188	STK3	T751	F747I	747	Missense	distal	-4	no	57.618	56.138	EPSD	COSMIC;CCLE	55.172	Down-regulation
STE_STE20_MST_STK3_ST	P00519	ABL1	Q13188	STK3	T751	D748N	748	Missense	distal	-3	no	57.618	59.296	EPSD	COSMIC	55.172	Up-regulation
STE_STE20_MST_STK3_ST	P00519	ABL1	Q13188	STK3	T814	R820W	820	Missense	distal	6	no	55.272	49.676	EPSD	COSMIC;CCLE	55.172	Loss
STE_STE20_MST_STK3_ST	P00519	ABL1	Q13188	STK3	T814	P817L	817	Missense	distal	3	no	55.272	54.634	EPSD	COSMIC	55.172	Loss
STE_STE20_MST_STK3_ST	P00519	ABL1	Q13188	STK3	T814	G807S	807	Missense	distal	-7	no	55.272	54.375	EPSD	COSMIC	55.172	Loss
STE_STE20_MST_STK3_ST	P00519	ABL1	Q13188	STK3	T814	N812T	812	Missense	proximal	-2	no	55.272	55.604	EPSD	COSMIC	55.172	Up-regulation
STE_STE20_MST_STK3_ST	P00519	ABL1	Q13188	STK3	T844	P850S	850	Missense	distal	6	no	49.719	57.001	EPSD	COSMIC	55.172	Gain
STE_STE20_MST_STK3_ST	P00519	ABL1	Q13188	STK3	S884	G890E	890	Missense	distal	6	no	53.039	56.758	EPSD	COSMIC	55.172	Gain
STE_STE20_MST_STK3_ST	P00519	ABL1	Q13188	STK3	S936	S943T	943	Missense	distal	7	no	71.838	74.593	EPSD	COSMIC	55.172	Up-regulation
STE_STE20_MST_STK3_ST	P00519	ABL1	Q13188	STK3	S949	D944N	944	Missense	distal	-5	no	49.398	56.520	EPSD	COSMIC	55.172	Gain
STE_STE20_MST_STK3_ST	P00519	ABL1	Q13188	STK3	S989	S990L	990	Missense	proximal	1	no	52.017	65.195	EPSD	COSMIC	55.172	Gain
STE_STE20_MST_STK3_ST	P00519	ABL1	Q13188	STK3	S1119	F1114L	1114	Missense	distal	-5	no	50.505	59.917	EPSD	COSMIC	55.172	Gain
STE_STE20_MST_STK3_ST	Q7L9L4	MOB1B	Q13188	STK3	T12	R8H	8	Missense	distal	-4	no	96.089	95.834	EPSD;PhosphoSitePlus	COSMIC;CCLE	55.172	Down-regulation
STE_STE20_MST_STK3_ST	Q7L9L4	MOB1B	Q13188	STK3	T12	K11T	11	Missense	proximal	-1	no	96.089	96.585	EPSD;PhosphoSitePlus	COSMIC	55.172	Up-regulation
STE_STE20_MST_STK3_ST	Q7L9L4	MOB1B	Q13188	STK3	T35	R42W	42	Missense	distal	7	no	100.261	101.372	EPSD;PhosphoSitePlus	COSMIC	55.172	Up-regulation
STE_STE20_MST_STK3_ST	Q7L9L4	MOB1B	Q13188	STK3	T35	R42Q	42	Missense	distal	7	no	100.261	99.456	EPSD;PhosphoSitePlus	COSMIC	55.172	Down-regulation
STE_STE20_MST_STK3_ST	Q7L9L4	MOB1B	Q13188	STK3	T35	A32T	32	Missense	distal	-3	no	100.261	100.957	EPSD;PhosphoSitePlus	COSMIC;GDSC;CCLE	55.172	Up-regulation
STE_STE20_MST_STK3_ST	Q7L9L4	MOB1B	Q13188	STK3	T35	A34T	34	Missense	proximal	-1	no	100.261	101.083	EPSD;PhosphoSitePlus	COSMIC	55.172	Up-regulation
STE_STE20_MST_STK3_ST	Q7L9L4	MOB1B	Q13188	STK3	T74	L71H	71	Missense	distal	-3	no	100.146	98.156	PhosphoSitePlus;EPSD	COSMIC	55.172	Down-regulation
STE_STE20_MST_STK3_ST	Q9H4B6	SAV1	Q13188	STK3	T26	V22E	22	Missense	distal	-4	no	96.976	95.327	EPSD;PhosphoSitePlus	COSMIC	55.172	Down-regulation
STE_STE20_MST_STK3_ST	Q9H4B6	SAV1	Q13188	STK3	T26	Y21H	21	Missense	distal	-5	no	96.976	102.126	EPSD;PhosphoSitePlus	COSMIC	55.172	Up-regulation
STE_STE20_MST_STK3_ST	Q9H4B6	SAV1	Q13188	STK3	S27	V22E	22	Missense	distal	-5	no	81.901	87.842	EPSD;PhosphoSitePlus	COSMIC	55.172	Up-regulation
STE_STE20_MST_STK3_ST	Q9H4B6	SAV1	Q13188	STK3	S27	Y21H	21	Missense	distal	-6	no	81.901	81.470	EPSD;PhosphoSitePlus	COSMIC	55.172	Down-regulation
STE_STE20_MST_STK3_ST	Q9H4B6	SAV1	Q13188	STK3	S36	T43R	43	Missense	distal	7	no	94.363	93.538	PhosphoSitePlus;EPSD	COSMIC	55.172	Down-regulation
STE_STE20_MST_STK3_ST	Q9H4B6	SAV1	Q13188	STK3	T81	P82L	82	Missense	proximal	1	no	42.819	61.253	EPSD	COSMIC	55.172	Gain
STE_STE20_MST_STK3_ST	Q9H4B6	SAV1	Q13188	STK3	T186	A185D	185	Missense	proximal	-1	no	53.815	55.450	EPSD	COSMIC;GDSC;CCLE	55.172	Gain
STE_STE20_MST_STK3_ST	Q9H8S9	MOB1A	Q13188	STK3	T12	K17R	17	Missense	distal	5	no	101.150	101.737	EPSD;PhosphoSitePlus	COSMIC	55.172	Up-regulation
STE_STE20_MST_STK3_ST	Q9H8S9	MOB1A	Q13188	STK3	T12	R8H	8	Missense	distal	-4	no	101.150	100.895	EPSD;PhosphoSitePlus	COSMIC;GDSC;CCLE	55.172	Down-regulation
STE_STE20_MST_STK3_ST	P51955	NEK2	Q13188	STK3	T175	F176C	176	Missense	proximal	1	no	62.472	4.148	EPSD	COSMIC	55.172	Loss
STE_STE20_MST_STK3_ST	P51955	NEK2	Q13188	STK3	S356	R361W	361	Missense	distal	5	no	91.920	92.551	EPSD;PhosphoSitePlus	COSMIC;GDSC;CCLE	55.172	Up-regulation
STE_STE20_MST_STK3_ST	P51955	NEK2	Q13188	STK3	S356	K353M	353	Missense	distal	-3	no	91.920	86.152	EPSD;PhosphoSitePlus	COSMIC;CCLE	55.172	Down-regulation
STE_STE20_MST_STK3_ST	P51955	NEK2	Q13188	STK3	S365	A367T	367	Missense	proximal	2	no	107.348	107.671	EPSD;PhosphoSitePlus	COSMIC	55.172	Up-regulation
STE_STE20_MST_STK3_ST	P51955	NEK2	Q13188	STK3	S365	R361W	361	Missense	distal	-4	no	107.348	108.062	EPSD;PhosphoSitePlus	COSMIC;GDSC;CCLE	55.172	Up-regulation
STE_STE20_MST_STK3_ST	P51955	NEK2	Q13188	STK3	S365	P370S	370	Missense	distal	5	no	107.348	105.631	EPSD;PhosphoSitePlus	COSMIC	55.172	Down-regulation
STE_STE20_MST_STK3_ST	P51955	NEK2	Q13188	STK3	T405	T405I	405	Missense	central	0	yes	57.833	0.000	EPSD	COSMIC	55.172	Loss
STE_STE20_MST_STK3_ST	P51955	NEK2	Q13188	STK3	T405	K411M	411	Missense	distal	6	no	57.833	48.387	EPSD	COSMIC	55.172	Loss
STE_STE20_MST_STK3_ST	P51955	NEK2	Q13188	STK3	S406	T405I	405	Missense	proximal	-1	no	92.917	94.834	PhosphoSitePlus;EPSD	COSMIC	55.172	Up-regulation
STE_STE20_MST_STK3_ST	P51955	NEK2	Q13188	STK3	S406	L413M	413	Missense	distal	7	no	92.917	91.785	PhosphoSitePlus;EPSD	COSMIC	55.172	Down-regulation
STE_STE20_MST_STK3_ST	P51955	NEK2	Q13188	STK3	S406	K411M	411	Missense	distal	5	no	92.917	92.715	PhosphoSitePlus;EPSD	COSMIC	55.172	Down-regulation
STE_STE20_MST_STK3_ST	P51955	NEK2	Q13188	STK3	S438	Q435K	435	Missense	distal	-3	no	73.331	75.201	EPSD;PhosphoSitePlus	COSMIC	55.172	Up-regulation
STE_STE20_MST_STK3_ST	P51955	NEK2	Q13188	STK3	S438	L436P	436	Missense	proximal	-2	no	73.331	72.503	EPSD;PhosphoSitePlus	COSMIC;GDSC	55.172	Down-regulation
STE_STE20_MST_STK3_ST	O95835	LATS1	Q13188	STK3	S27	I34M	34	Missense	distal	7	no	56.802	55.670	EPSD	COSMIC	55.172	Down-regulation
STE_STE20_MST_STK3_ST	O95835	LATS1	Q13188	STK3	S404	G403E	403	Missense	proximal	-1	no	61.600	57.220	EPSD	COSMIC	55.172	Down-regulation
STE_STE20_MST_STK3_ST	O95835	LATS1	Q13188	STK3	S404	P397L	397	Missense	distal	-7	no	61.600	61.205	EPSD	COSMIC	55.172	Down-regulation
STE_STE20_MST_STK3_ST	O95835	LATS1	Q13188	STK3	S575	P572S	572	Missense	distal	-3	no	54.722	57.476	EPSD	COSMIC	55.172	Gain
STE_STE20_MST_STK3_ST	O95835	LATS1	Q13188	STK3	S872	E878D	878	Missense	distal	6	no	89.781	86.079	EPSD;PhosphoSitePlus	COSMIC	55.172	Down-regulation
STE_STE20_MST_STK3_ST	O95835	LATS1	Q13188	STK3	S872	S876R	876	Missense	distal	4	no	89.781	90.262	EPSD;PhosphoSitePlus	COSMIC	55.172	Up-regulation
STE_STE20_MST_STK3_ST	O95835	LATS1	Q13188	STK3	S883	D889H	889	Missense	distal	6	no	55.923	56.559	EPSD	COSMIC	55.172	Up-regulation
STE_STE20_MST_STK3_ST	O95835	LATS1	Q13188	STK3	S883	E878D	878	Missense	distal	-5	no	55.923	44.424	EPSD	COSMIC	55.172	Loss
STE_STE20_MST_STK3_ST	O95835	LATS1	Q13188	STK3	S883	S876R	876	Missense	distal	-7	no	55.923	56.278	EPSD	COSMIC	55.172	Up-regulation
STE_STE20_MST_STK3_ST	O95835	LATS1	Q13188	STK3	S909	G912R	912	Missense	distal	3	no	108.035	106.229	PhosphoSitePlus;EPSD	COSMIC	55.172	Down-regulation
STE_STE20_MST_STK3_ST	O95835	LATS1	Q13188	STK3	S909	P914S	914	Missense	distal	5	no	108.035	106.318	PhosphoSitePlus;EPSD	COSMIC	55.172	Down-regulation
STE_STE20_MST_STK3_ST	O95835	LATS1	Q13188	STK3	S909	R904Q	904	Missense	distal	-5	no	108.035	103.053	PhosphoSitePlus;EPSD	COSMIC;CCLE	55.172	Down-regulation
STE_STE20_MST_STK3_ST	O95835	LATS1	Q13188	STK3	S909	S909Y	909	Missense	central	0	yes	108.035	0.000	PhosphoSitePlus;EPSD	COSMIC	55.172	Loss
STE_STE20_MST_STK3_ST	O95835	LATS1	Q13188	STK3	T967	M960I	960	Missense	distal	-7	no	92.439	92.659	EPSD;PhosphoSitePlus	COSMIC	55.172	Up-regulation
STE_STE20_MST_STK3_ST	O95835	LATS1	Q13188	STK3	T967	P973T	973	Missense	distal	6	no	92.439	93.024	EPSD;PhosphoSitePlus	COSMIC	55.172	Up-regulation
STE_STE20_MST_STK3_ST	O95835	LATS1	Q13188	STK3	T967	Q966R	966	Missense	proximal	-1	no	92.439	94.059	EPSD;PhosphoSitePlus	COSMIC	55.172	Up-regulation
STE_STE20_MST_STK3_ST	O95835	LATS1	Q13188	STK3	T1012	K1005N	1005	Missense	distal	-7	no	96.824	97.441	EPSD;PhosphoSitePlus	COSMIC;GDSC;CCLE	55.172	Up-regulation
STE_STE20_MST_STK3_ST	O95835	LATS1	Q13188	STK3	T1060	D1059G	1059	Missense	proximal	-1	no	92.256	93.160	EPSD;PhosphoSitePlus	COSMIC	55.172	Up-regulation
STE_STE20_MST_STK3_ST	O95835	LATS1	Q13188	STK3	T1060	N1067H	1067	Missense	distal	7	no	92.256	93.872	EPSD;PhosphoSitePlus	COSMIC	55.172	Up-regulation
STE_STE20_MST_STK3_ST	O95835	LATS1	Q13188	STK3	T1060	G1063V	1063	Missense	distal	3	no	92.256	90.426	EPSD;PhosphoSitePlus	COSMIC	55.172	Down-regulation
STE_STE20_MST_STK3_ST	O95835	LATS1	Q13188	STK3	T1060	K1066R	1066	Missense	distal	6	no	92.256	86.645	EPSD;PhosphoSitePlus	COSMIC	55.172	Down-regulation
STE_STE20_MST_STK3_ST	O95835	LATS1	Q13188	STK3	T1079	A1074V	1074	Missense	distal	-5	no	94.072	96.982	EPSD;PhosphoSitePlus	COSMIC	55.172	Up-regulation
STE_STE20_MST_STK3_ST	O95835	LATS1	Q13188	STK3	T1079	F1075L	1075	Missense	distal	-4	no	94.072	91.076	EPSD;PhosphoSitePlus	COSMIC	55.172	Down-regulation
STE_STE20_MST_STK3_ST	Q13188	STK3	Q13188	STK3	S18	P23L	23	Missense	distal	5	no	63.339	63.923	EPSD	COSMIC	55.172	Up-regulation
STE_STE20_MST_STK3_ST	Q13188	STK3	Q13188	STK3	S18	S18C	18	Missense	central	0	yes	63.339	0.000	EPSD	COSMIC	55.172	Loss
STE_STE20_MST_STK3_ST	Q13188	STK3	Q13188	STK3	S18	E16D	16	Missense	proximal	-2	no	63.339	63.711	EPSD	COSMIC	55.172	Up-regulation
STE_STE20_MST_STK3_ST	Q13188	STK3	Q13188	STK3	S72	S79I	79	Missense	distal	7	no	54.521	57.118	EPSD	COSMIC	55.172	Gain
STE_STE20_MST_STK3_ST	Q13188	STK3	Q13188	STK3	S72	I73L	73	Missense	proximal	1	no	54.521	61.722	EPSD	COSMIC	55.172	Gain
STE_STE20_MST_STK3_ST	Q13188	STK3	Q13188	STK3	S72	S79G	79	Missense	distal	7	no	54.521	57.174	EPSD	COSMIC	55.172	Gain
STE_STE20_MST_STK3_ST	Q13188	STK3	Q13188	STK3	S72	I67V	67	Missense	distal	-5	no	54.521	61.217	EPSD	COSMIC	55.172	Gain
STE_STE20_MST_STK3_ST	Q13188	STK3	Q13188	STK3	T180	N179S	179	Missense	proximal	-1	no	98.008	96.522	PhosphoSitePlus;EPSD	COSMIC;CCLE	55.172	Down-regulation
STE_STE20_MST_STK3_ST	Q13188	STK3	Q13188	STK3	T180	D173Y	173	Missense	distal	-7	no	98.008	97.228	PhosphoSitePlus;EPSD	COSMIC	55.172	Down-regulation
STE_STE20_MST_STK3_ST	Q13188	STK3	Q13188	STK3	T180	R178H	178	Missense	proximal	-2	no	98.008	97.075	PhosphoSitePlus;EPSD	COSMIC;GDSC;CCLE	55.172	Down-regulation
STE_STE20_MST_STK3_ST	Q13188	STK3	Q13188	STK3	T180	R178C	178	Missense	proximal	-2	no	98.008	94.621	PhosphoSitePlus;EPSD	COSMIC	55.172	Down-regulation
STE_STE20_MST_STK3_ST	Q13188	STK3	Q13188	STK3	T180	D173V	173	Missense	distal	-7	no	98.008	96.759	PhosphoSitePlus;EPSD	COSMIC	55.172	Down-regulation
STE_STE20_MST_STK3_ST	Q13188	STK3	Q13188	STK3	T180	A176S	176	Missense	distal	-4	no	98.008	96.563	PhosphoSitePlus;EPSD	COSMIC	55.172	Down-regulation
STE_STE20_MST_STK3_ST	Q13188	STK3	Q13188	STK3	T180	V181L	181	Missense	proximal	1	no	98.008	112.383	PhosphoSitePlus;EPSD	COSMIC	55.172	Up-regulation
STE_STE20_MST_STK3_ST	Q13188	STK3	Q13188	STK3	T180	F186L	186	Missense	distal	6	no	98.008	101.337	PhosphoSitePlus;EPSD	COSMIC	55.172	Up-regulation
STE_STE20_MST_STK3_ST	Q13188	STK3	Q13188	STK3	S333	K328N	328	Missense	distal	-5	no	58.060	57.038	EPSD	COSMIC	55.172	Down-regulation
STE_STE20_MST_STK3_ST	Q13188	STK3	Q13188	STK3	T364	G363D	363	Missense	proximal	-1	no	63.595	62.691	EPSD	COSMIC	55.172	Down-regulation
STE_STE20_MST_STK3_ST	Q13188	STK3	Q13188	STK3	T364	D371G	371	Missense	distal	7	no	63.595	63.102	EPSD	COSMIC	55.172	Down-regulation
STE_STE20_MST_STK3_ST	Q13188	STK3	Q13188	STK3	T364	L358F	358	Missense	distal	-6	no	63.595	61.261	EPSD	COSMIC	55.172	Down-regulation
STE_STE20_MST_STK3_ST	Q13188	STK3	Q13188	STK3	T364	D371N	371	Missense	distal	7	no	63.595	60.565	EPSD	COSMIC	55.172	Down-regulation
STE_STE20_MST_STK3_ST	Q13188	STK3	Q13188	STK3	T378	E373K	373	Missense	distal	-5	no	104.081	100.726	EPSD;PhosphoSitePlus	COSMIC	55.172	Down-regulation
STE_STE20_MST_STK3_ST	Q13188	STK3	Q13188	STK3	T378	D371G	371	Missense	distal	-7	no	104.081	103.709	EPSD;PhosphoSitePlus	COSMIC	55.172	Down-regulation
STE_STE20_MST_STK3_ST	Q13188	STK3	Q13188	STK3	T378	T378A	378	Missense	central	0	yes	104.081	0.000	EPSD;PhosphoSitePlus	COSMIC	55.172	Loss
STE_STE20_MST_STK3_ST	Q13188	STK3	Q13188	STK3	T378	D371N	371	Missense	distal	-7	no	104.081	102.778	EPSD;PhosphoSitePlus	COSMIC	55.172	Down-regulation
STE_STE20_MST_STK3_ST	P46937	YAP1	Q13188	STK3	S127	L132R	132	Missense	distal	5	no	88.207	88.134	PhosphoSitePlus	COSMIC	55.172	Down-regulation
STE_STE20_MST_STK3_ST	P46937	YAP1	Q13188	STK3	S127	Q133H	133	Missense	distal	6	no	88.207	80.014	PhosphoSitePlus	COSMIC	55.172	Down-regulation
STE_STE20_MST_STK3_ST	P46937	YAP1	Q13188	STK3	S127	S127F	127	Missense	central	0	yes	88.207	0.000	PhosphoSitePlus	COSMIC	55.172	Loss
STE_STE20_MST_STK3_ST	P46937	YAP1	Q13188	STK3	S127	A125G	125	Missense	proximal	-2	no	88.207	86.479	PhosphoSitePlus	COSMIC	55.172	Down-regulation
STE_STE20_MST_STK3_ST	P46937	YAP1	Q13188	STK3	S131	L132R	132	Missense	proximal	1	no	59.720	31.804	EPSD	COSMIC	55.172	Loss
STE_STE20_MST_STK3_ST	P46937	YAP1	Q13188	STK3	S131	Q133H	133	Missense	proximal	2	no	59.720	61.030	EPSD	COSMIC	55.172	Up-regulation
STE_STE20_MST_STK3_ST	P46937	YAP1	Q13188	STK3	S131	S127F	127	Missense	distal	-4	no	59.720	62.946	EPSD	COSMIC	55.172	Up-regulation
STE_STE20_MST_STK3_ST	P46937	YAP1	Q13188	STK3	S131	A125G	125	Missense	distal	-6	no	59.720	56.429	EPSD	COSMIC	55.172	Down-regulation
STE_STE20_MST_STK3_ST	P46937	YAP1	Q13188	STK3	S274	V279L	279	Missense	distal	5	no	56.361	56.813	EPSD	COSMIC	55.172	Up-regulation
STE_STE20_MST_STK3_ST	P46937	YAP1	Q13188	STK3	S274	S274G	274	Missense	central	0	yes	56.361	0.000	EPSD	COSMIC	55.172	Loss
STE_STE20_MST_STK3_ST	P46937	YAP1	Q13188	STK3	S274	P278S	278	Missense	distal	4	no	56.361	55.569	EPSD	COSMIC	55.172	Down-regulation
STE_STE20_MST_STK3_ST	P46937	YAP1	Q13188	STK3	S274	S276R	276	Missense	proximal	2	no	56.361	57.496	EPSD	COSMIC	55.172	Up-regulation
STE_STE20_MST_STK3_ST	P46937	YAP1	Q13188	STK3	S274	A268V	268	Missense	distal	-6	no	56.361	55.913	EPSD	COSMIC	55.172	Down-regulation
STE_STE20_MST_STK3_ST	P46937	YAP1	Q13188	STK3	S274	Q281H	281	Missense	distal	7	no	56.361	56.967	EPSD	COSMIC	55.172	Up-regulation
STE_STE20_MST_STK3_ST	P46937	YAP1	Q13188	STK3	T361	S367F	367	Missense	distal	6	no	59.163	48.000	EPSD	COSMIC	55.172	Loss
STE_STE20_MST_STK3_ST	P46937	YAP1	Q13188	STK3	S405	R411Q	411	Missense	distal	6	no	53.006	57.493	EPSD	COSMIC	55.172	Gain
Atypical_PIKK_ATR_ATR_ST	P25205	MCM3	Q13535	ATR	T384	T384A	384	Missense	central	0	yes	12.591	0.000	EPSD	COSMIC	10.658	Loss
Atypical_PIKK_ATR_ATR_ST	P25205	MCM3	Q13535	ATR	T384	R391H	391	Missense	distal	7	no	12.591	12.620	EPSD	COSMIC	10.658	Up-regulation
Atypical_PIKK_ATR_ATR_ST	P25205	MCM3	Q13535	ATR	T384	T379R	379	Missense	distal	-5	no	12.591	12.761	EPSD	COSMIC	10.658	Up-regulation
Atypical_PIKK_ATR_ATR_ST	P25205	MCM3	Q13535	ATR	S477	R478Q	478	Missense	proximal	1	no	5.250	12.245	EPSD	COSMIC	10.658	Gain
Atypical_PIKK_ATR_ATR_ST	P25205	MCM3	Q13535	ATR	S535	D530H	530	Missense	distal	-5	no	16.849	16.801	PhosphoSitePlus	COSMIC	10.658	Down-regulation
Atypical_PIKK_ATR_ATR_ST	P25205	MCM3	Q13535	ATR	S535	Q536H	536	Missense	proximal	1	no	16.849	-0.669	PhosphoSitePlus	COSMIC	10.658	Loss
Atypical_PIKK_ATR_ATR_ST	P25205	MCM3	Q13535	ATR	S535	T529K	529	Missense	distal	-6	no	16.849	16.772	PhosphoSitePlus	COSMIC	10.658	Down-regulation
Atypical_PIKK_ATR_ATR_ST	P25205	MCM3	Q13535	ATR	T542	Y545S	545	Missense	distal	3	no	11.598	12.516	EPSD	COSMIC	10.658	Up-regulation
Atypical_PIKK_ATR_ATR_ST	P25205	MCM3	Q13535	ATR	T542	Q536H	536	Missense	distal	-6	no	11.598	11.613	EPSD	COSMIC	10.658	Up-regulation
Atypical_PIKK_ATR_ATR_ST	P25205	MCM3	Q13535	ATR	S599	R596H	596	Missense	distal	-3	no	14.494	14.125	EPSD	COSMIC	10.658	Down-regulation
Atypical_PIKK_ATR_ATR_ST	P25205	MCM3	Q13535	ATR	S599	M603L	603	Missense	distal	4	no	14.494	15.175	EPSD	COSMIC	10.658	Up-regulation
Atypical_PIKK_ATR_ATR_ST	P25205	MCM3	Q13535	ATR	S602	R596H	596	Missense	distal	-6	no	11.453	11.459	EPSD	COSMIC	10.658	Up-regulation
Atypical_PIKK_ATR_ATR_ST	P25205	MCM3	Q13535	ATR	S602	A608T	608	Missense	distal	6	no	11.453	11.732	EPSD	COSMIC	10.658	Up-regulation
Atypical_PIKK_ATR_ATR_ST	P25205	MCM3	Q13535	ATR	S602	M603L	603	Missense	proximal	1	no	11.453	10.105	EPSD	COSMIC	10.658	Loss
Atypical_PIKK_ATR_ATR_ST	P25205	MCM3	Q13535	ATR	S681	K688N	688	Missense	distal	7	no	14.401	14.672	EPSD	COSMIC	10.658	Up-regulation
Atypical_PIKK_ATR_ATR_ST	P25205	MCM3	Q13535	ATR	S681	D676N	676	Missense	distal	-5	no	14.401	14.375	EPSD	COSMIC	10.658	Down-regulation
Atypical_PIKK_ATR_ATR_ST	P25205	MCM3	Q13535	ATR	S681	Q685H	685	Missense	distal	4	no	14.401	14.113	EPSD	COSMIC	10.658	Down-regulation
Atypical_PIKK_ATR_ATR_ST	P25205	MCM3	Q13535	ATR	S681	E683K	683	Missense	proximal	2	no	14.401	13.452	EPSD	COSMIC	10.658	Down-regulation
Atypical_PIKK_ATR_ATR_ST	P25205	MCM3	Q13535	ATR	T713	D706N	706	Missense	distal	-7	no	12.026	11.908	EPSD	COSMIC	10.658	Down-regulation
Atypical_PIKK_ATR_ATR_ST	P25205	MCM3	Q13535	ATR	T713	P707S	707	Missense	distal	-6	no	12.026	11.981	EPSD	COSMIC	10.658	Down-regulation
Atypical_PIKK_ATR_ATR_ST	P25205	MCM3	Q13535	ATR	T713	P718L	718	Missense	distal	5	no	12.026	12.021	EPSD	COSMIC	10.658	Down-regulation
Atypical_PIKK_ATR_ATR_ST	P25205	MCM3	Q13535	ATR	T713	E714K	714	Missense	proximal	1	no	12.026	6.980	EPSD	COSMIC	10.658	Loss
Atypical_PIKK_ATR_ATR_ST	P25205	MCM3	Q13535	ATR	S728	E730K	730	Missense	proximal	2	no	21.461	20.512	EPSD	COSMIC	10.658	Down-regulation
Atypical_PIKK_ATR_ATR_ST	P25205	MCM3	Q13535	ATR	S728	A726T	726	Missense	proximal	-2	no	21.461	20.988	EPSD	COSMIC	10.658	Down-regulation
Atypical_PIKK_ATR_ATR_ST	P25205	MCM3	Q13535	ATR	S728	D727E	727	Missense	proximal	-1	no	21.461	21.416	EPSD	COSMIC	10.658	Down-regulation
Atypical_PIKK_ATR_ATR_ST	P25205	MCM3	Q13535	ATR	S734	E730K	730	Missense	distal	-4	no	13.388	12.978	EPSD	COSMIC	10.658	Down-regulation
Atypical_PIKK_ATR_ATR_ST	P25205	MCM3	Q13535	ATR	S734	D727E	727	Missense	distal	-7	no	13.388	13.434	EPSD	COSMIC	10.658	Up-regulation
Atypical_PIKK_ATR_ATR_ST	P25205	MCM3	Q13535	ATR	S734	E741D	741	Missense	distal	7	no	13.388	13.583	EPSD	COSMIC	10.658	Up-regulation
Atypical_PIKK_ATR_ATR_ST	P25205	MCM3	Q13535	ATR	S734	V737A	737	Missense	distal	3	no	13.388	12.628	EPSD	COSMIC	10.658	Down-regulation
Atypical_PIKK_ATR_ATR_ST	P25205	MCM3	Q13535	ATR	S742	R743M	743	Missense	proximal	1	no	8.392	11.302	EPSD	COSMIC	10.658	Gain
Atypical_PIKK_ATR_ATR_ST	O60934	NBN	Q13535	ATR	S58	V65I	65	Missense	distal	7	no	11.537	11.646	EPSD	COSMIC	10.658	Up-regulation
Atypical_PIKK_ATR_ATR_ST	O60934	NBN	Q13535	ATR	S58	V65A	65	Missense	distal	7	no	11.537	11.397	EPSD	COSMIC	10.658	Down-regulation
Atypical_PIKK_ATR_ATR_ST	O60934	NBN	Q13535	ATR	S58	L57Q	57	Missense	proximal	-1	no	11.537	11.358	EPSD	COSMIC	10.658	Down-regulation
Atypical_PIKK_ATR_ATR_ST	O60934	NBN	Q13535	ATR	T60	V65I	65	Missense	distal	5	no	11.017	11.027	EPSD	COSMIC	10.658	Up-regulation
Atypical_PIKK_ATR_ATR_ST	O60934	NBN	Q13535	ATR	T60	V65A	65	Missense	distal	5	no	11.017	11.026	EPSD	COSMIC	10.658	Up-regulation
Atypical_PIKK_ATR_ATR_ST	O60934	NBN	Q13535	ATR	T60	L57Q	57	Missense	distal	-3	no	11.017	10.798	EPSD	COSMIC	10.658	Down-regulation
Atypical_PIKK_ATR_ATR_ST	O60934	NBN	Q13535	ATR	T67	V65I	65	Missense	proximal	-2	no	10.575	10.816	EPSD	COSMIC	10.658	Gain
Atypical_PIKK_ATR_ATR_ST	O60934	NBN	Q13535	ATR	T67	V65A	65	Missense	proximal	-2	no	10.575	11.094	EPSD	COSMIC	10.658	Gain
Atypical_PIKK_ATR_ATR_ST	O60934	NBN	Q13535	ATR	S278	D284H	284	Missense	distal	6	no	15.706	15.574	EPSD	COSMIC	10.658	Down-regulation
Atypical_PIKK_ATR_ATR_ST	O60934	NBN	Q13535	ATR	S278	D272N	272	Missense	distal	-6	no	15.706	15.709	EPSD	COSMIC	10.658	Up-regulation
Atypical_PIKK_ATR_ATR_ST	O60934	NBN	Q13535	ATR	S278	N277S	277	Missense	proximal	-1	no	15.706	15.229	EPSD	COSMIC	10.658	Down-regulation
Atypical_PIKK_ATR_ATR_ST	O60934	NBN	Q13535	ATR	T337	L342H	342	Missense	distal	5	no	11.429	11.427	EPSD	COSMIC	10.658	Down-regulation
Atypical_PIKK_ATR_ATR_ST	O60934	NBN	Q13535	ATR	T337	P338S	338	Missense	proximal	1	no	11.429	10.320	EPSD	COSMIC	10.658	Loss
Atypical_PIKK_ATR_ATR_ST	O60934	NBN	Q13535	ATR	S343	L342H	342	Missense	proximal	-1	no	16.611	16.397	PhosphoSitePlus;EPSD	COSMIC	10.658	Down-regulation
Atypical_PIKK_ATR_ATR_ST	O60934	NBN	Q13535	ATR	S343	V346M	346	Missense	distal	3	no	16.611	15.821	PhosphoSitePlus;EPSD	COSMIC	10.658	Down-regulation
Atypical_PIKK_ATR_ATR_ST	O60934	NBN	Q13535	ATR	S343	P338S	338	Missense	distal	-5	no	16.611	16.582	PhosphoSitePlus;EPSD	COSMIC	10.658	Down-regulation
Atypical_PIKK_ATR_ATR_ST	O60934	NBN	Q13535	ATR	S369	Y363H	363	Missense	distal	-6	no	11.923	11.838	EPSD	COSMIC	10.658	Down-regulation
Atypical_PIKK_ATR_ATR_ST	O60934	NBN	Q13535	ATR	S369	A372V	372	Missense	distal	3	no	11.923	12.683	EPSD	COSMIC	10.658	Up-regulation
Atypical_PIKK_ATR_ATR_ST	O60934	NBN	Q13535	ATR	S369	D373H	373	Missense	distal	4	no	11.923	11.573	EPSD	COSMIC	10.658	Down-regulation
Atypical_PIKK_ATR_ATR_ST	O60934	NBN	Q13535	ATR	S369	W375C	375	Missense	distal	6	no	11.923	12.037	EPSD	COSMIC	10.658	Up-regulation
Atypical_PIKK_ATR_ATR_ST	O60934	NBN	Q13535	ATR	S369	A365P	365	Missense	distal	-4	no	11.923	11.727	EPSD	COSMIC	10.658	Down-regulation
Atypical_PIKK_ATR_ATR_ST	O60934	NBN	Q13535	ATR	S397	R394I	394	Missense	distal	-3	no	13.700	13.187	EPSD	COSMIC	10.658	Down-regulation
Atypical_PIKK_ATR_ATR_ST	O60934	NBN	Q13535	ATR	S397	R394G	394	Missense	distal	-3	no	13.700	13.204	EPSD	COSMIC	10.658	Down-regulation
Atypical_PIKK_ATR_ATR_ST	O60934	NBN	Q13535	ATR	S415	V417G	417	Missense	proximal	2	no	13.308	13.610	EPSD	COSMIC	10.658	Up-regulation
Atypical_PIKK_ATR_ATR_ST	O60934	NBN	Q13535	ATR	S415	S411C	411	Missense	distal	-4	no	13.308	12.019	EPSD	COSMIC	10.658	Down-regulation
Atypical_PIKK_ATR_ATR_ST	O60934	NBN	Q13535	ATR	T493	P498L	498	Missense	distal	5	no	13.766	13.761	EPSD	COSMIC	10.658	Down-regulation
Atypical_PIKK_ATR_ATR_ST	O60934	NBN	Q13535	ATR	T493	S486F	486	Missense	distal	-7	no	13.766	13.658	EPSD	COSMIC	10.658	Down-regulation
Atypical_PIKK_ATR_ATR_ST	O60934	NBN	Q13535	ATR	S615	S615F	615	Missense	central	0	yes	17.909	0.000	EPSD;PhosphoSitePlus	COSMIC	10.658	Loss
Atypical_PIKK_ATR_ATR_ST	O60934	NBN	Q13535	ATR	S615	Q616K	616	Missense	proximal	1	no	17.909	6.943	EPSD;PhosphoSitePlus	COSMIC	10.658	Loss
Atypical_PIKK_ATR_ATR_ST	O60934	NBN	Q13535	ATR	S615	V608I	608	Missense	distal	-7	no	17.909	17.848	EPSD;PhosphoSitePlus	COSMIC	10.658	Down-regulation
Atypical_PIKK_ATR_ATR_ST	O60934	NBN	Q13535	ATR	S661	S667P	667	Missense	distal	6	no	11.592	11.295	EPSD	COSMIC;GDSC;CCLE	10.658	Down-regulation
Atypical_PIKK_ATR_ATR_ST	O60934	NBN	Q13535	ATR	S661	I664M	664	Missense	distal	3	no	11.592	10.892	EPSD	COSMIC	10.658	Down-regulation
Atypical_PIKK_ATR_ATR_ST	O60934	NBN	Q13535	ATR	S661	R660I	660	Missense	proximal	-1	no	11.592	11.737	EPSD	COSMIC	10.658	Up-regulation
Atypical_PIKK_ATR_ATR_ST	O60934	NBN	Q13535	ATR	S661	E658K	658	Missense	distal	-3	no	11.592	11.317	EPSD	COSMIC	10.658	Down-regulation
Atypical_PIKK_ATR_ATR_ST	O60934	NBN	Q13535	ATR	S661	L656M	656	Missense	distal	-5	no	11.592	11.307	EPSD	COSMIC	10.658	Down-regulation
Atypical_PIKK_ATR_ATR_ST	O60934	NBN	Q13535	ATR	S661	T657A	657	Missense	distal	-4	no	11.592	12.200	EPSD	COSMIC	10.658	Up-regulation
Atypical_PIKK_ATR_ATR_ST	O60934	NBN	Q13535	ATR	S661	S667C	667	Missense	distal	6	no	11.592	11.409	EPSD	COSMIC	10.658	Down-regulation
Atypical_PIKK_ATR_ATR_ST	O60934	NBN	Q13535	ATR	S738	L739P	739	Missense	proximal	1	no	10.457	11.023	EPSD	COSMIC	10.658	Gain
Atypical_PIKK_ATR_ATR_ST	P78527	PRKDC	Q13535	ATR	S237	T235S	235	Missense	proximal	-2	no	13.188	12.886	EPSD	COSMIC	10.658	Down-regulation
Atypical_PIKK_ATR_ATR_ST	P78527	PRKDC	Q13535	ATR	S318	S324F	324	Missense	distal	6	no	12.371	12.213	EPSD	COSMIC	10.658	Down-regulation
Atypical_PIKK_ATR_ATR_ST	P78527	PRKDC	Q13535	ATR	S922	L919F	919	Missense	distal	-3	no	11.243	11.531	EPSD	COSMIC;GDSC;CCLE	10.658	Up-regulation
Atypical_PIKK_ATR_ATR_ST	P78527	PRKDC	Q13535	ATR	S922	A929T	929	Missense	distal	7	no	11.243	11.344	EPSD	COSMIC	10.658	Up-regulation
Atypical_PIKK_ATR_ATR_ST	P78527	PRKDC	Q13535	ATR	S922	A929E	929	Missense	distal	7	no	11.243	11.135	EPSD	COSMIC	10.658	Down-regulation
Atypical_PIKK_ATR_ATR_ST	P78527	PRKDC	Q13535	ATR	S936	S936C	936	Missense	central	0	yes	11.550	0.000	EPSD	COSMIC	10.658	Loss
Atypical_PIKK_ATR_ATR_ST	P78527	PRKDC	Q13535	ATR	S936	A929T	929	Missense	distal	-7	no	11.550	11.527	EPSD	COSMIC	10.658	Down-regulation
Atypical_PIKK_ATR_ATR_ST	P78527	PRKDC	Q13535	ATR	S936	A929E	929	Missense	distal	-7	no	11.550	11.615	EPSD	COSMIC	10.658	Up-regulation
Atypical_PIKK_ATR_ATR_ST	P78527	PRKDC	Q13535	ATR	T946	T946M	946	Missense	central	0	yes	13.230	0.000	EPSD	COSMIC	10.658	Loss
Atypical_PIKK_ATR_ATR_ST	P78527	PRKDC	Q13535	ATR	S1352	S1352P	1352	Missense	central	0	yes	11.678	0.000	EPSD	COSMIC	10.658	Loss
Atypical_PIKK_ATR_ATR_ST	P78527	PRKDC	Q13535	ATR	S1352	P1353L	1353	Missense	proximal	1	no	11.678	11.112	EPSD	COSMIC	10.658	Down-regulation
Atypical_PIKK_ATR_ATR_ST	P78527	PRKDC	Q13535	ATR	S1352	G1355E	1355	Missense	distal	3	no	11.678	11.858	EPSD	COSMIC	10.658	Up-regulation
Atypical_PIKK_ATR_ATR_ST	P78527	PRKDC	Q13535	ATR	S1352	P1353S	1353	Missense	proximal	1	no	11.678	10.569	EPSD	COSMIC	10.658	Loss
Atypical_PIKK_ATR_ATR_ST	P78527	PRKDC	Q13535	ATR	S1546	Q1547H	1547	Missense	proximal	1	no	14.724	-2.794	EPSD	COSMIC	10.658	Loss
Atypical_PIKK_ATR_ATR_ST	P78527	PRKDC	Q13535	ATR	S1546	G1544D	1544	Missense	proximal	-2	no	14.724	14.803	EPSD	COSMIC	10.658	Up-regulation
Atypical_PIKK_ATR_ATR_ST	P78527	PRKDC	Q13535	ATR	S1546	V1550I	1550	Missense	distal	4	no	14.724	15.244	EPSD	COSMIC	10.658	Up-regulation
Atypical_PIKK_ATR_ATR_ST	P78527	PRKDC	Q13535	ATR	S1546	G1548D	1548	Missense	proximal	2	no	14.724	13.178	EPSD	COSMIC	10.658	Down-regulation
Atypical_PIKK_ATR_ATR_ST	P78527	PRKDC	Q13535	ATR	T1793	R1788K	1788	Missense	distal	-5	no	13.596	13.411	EPSD	COSMIC	10.658	Down-regulation
Atypical_PIKK_ATR_ATR_ST	P78527	PRKDC	Q13535	ATR	T1793	R1788S	1788	Missense	distal	-5	no	13.596	13.414	EPSD	COSMIC	10.658	Down-regulation
Atypical_PIKK_ATR_ATR_ST	P78527	PRKDC	Q13535	ATR	T1793	L1797F	1797	Missense	distal	4	no	13.596	13.377	EPSD	COSMIC	10.658	Down-regulation
Atypical_PIKK_ATR_ATR_ST	P78527	PRKDC	Q13535	ATR	T1793	G1796S	1796	Missense	distal	3	no	13.596	14.089	EPSD	COSMIC	10.658	Up-regulation
Atypical_PIKK_ATR_ATR_ST	P78527	PRKDC	Q13535	ATR	T1793	E1799G	1799	Missense	distal	6	no	13.596	13.268	EPSD	COSMIC	10.658	Down-regulation
Atypical_PIKK_ATR_ATR_ST	P78527	PRKDC	Q13535	ATR	T1865	T1868I	1868	Missense	distal	3	no	10.466	10.824	EPSD	COSMIC	10.658	Gain
Atypical_PIKK_ATR_ATR_ST	P78527	PRKDC	Q13535	ATR	S2041	G2048E	2048	Missense	distal	7	no	12.885	12.880	EPSD	COSMIC	10.658	Down-regulation
Atypical_PIKK_ATR_ATR_ST	P78527	PRKDC	Q13535	ATR	S2041	M2040I	2040	Missense	proximal	-1	no	12.885	12.987	EPSD	COSMIC	10.658	Up-regulation
Atypical_PIKK_ATR_ATR_ST	P78527	PRKDC	Q13535	ATR	S2041	S2046L	2046	Missense	distal	5	no	12.885	12.892	EPSD	COSMIC	10.658	Up-regulation
Atypical_PIKK_ATR_ATR_ST	P78527	PRKDC	Q13535	ATR	S2041	S2037I	2037	Missense	distal	-4	no	12.885	11.543	EPSD	COSMIC	10.658	Down-regulation
Atypical_PIKK_ATR_ATR_ST	P78527	PRKDC	Q13535	ATR	S2041	G2048A	2048	Missense	distal	7	no	12.885	12.989	EPSD	COSMIC	10.658	Up-regulation
Atypical_PIKK_ATR_ATR_ST	P78527	PRKDC	Q13535	ATR	S2041	F2045I	2045	Missense	distal	4	no	12.885	13.549	EPSD	COSMIC	10.658	Up-regulation
Atypical_PIKK_ATR_ATR_ST	P78527	PRKDC	Q13535	ATR	S2041	G2048R	2048	Missense	distal	7	no	12.885	13.142	EPSD	COSMIC	10.658	Up-regulation
Atypical_PIKK_ATR_ATR_ST	P78527	PRKDC	Q13535	ATR	S2041	Q2042K	2042	Missense	proximal	1	no	12.885	1.919	EPSD	COSMIC	10.658	Loss
Atypical_PIKK_ATR_ATR_ST	P78527	PRKDC	Q13535	ATR	S2056	A2062T	2062	Missense	distal	6	no	11.207	11.485	EPSD	COSMIC	10.658	Up-regulation
Atypical_PIKK_ATR_ATR_ST	P78527	PRKDC	Q13535	ATR	S2056	P2059A	2059	Missense	distal	3	no	11.207	10.609	EPSD	COSMIC	10.658	Loss
Atypical_PIKK_ATR_ATR_ST	P78527	PRKDC	Q13535	ATR	S2056	D2058N	2058	Missense	proximal	2	no	11.207	12.127	EPSD	COSMIC	10.658	Up-regulation
Atypical_PIKK_ATR_ATR_ST	P78527	PRKDC	Q13535	ATR	S2056	S2055R	2055	Missense	proximal	-1	no	11.207	11.334	EPSD	COSMIC	10.658	Up-regulation
Atypical_PIKK_ATR_ATR_ST	P78527	PRKDC	Q13535	ATR	T2609	L2616V	2616	Missense	distal	7	no	15.839	15.888	PhosphoSitePlus;EPSD	COSMIC	10.658	Up-regulation
Atypical_PIKK_ATR_ATR_ST	P78527	PRKDC	Q13535	ATR	T2609	M2605I	2605	Missense	distal	-4	no	15.839	14.716	PhosphoSitePlus;EPSD	COSMIC	10.658	Down-regulation
Atypical_PIKK_ATR_ATR_ST	P78527	PRKDC	Q13535	ATR	T2609	L2602F	2602	Missense	distal	-7	no	15.839	15.897	PhosphoSitePlus;EPSD	COSMIC	10.658	Up-regulation
Atypical_PIKK_ATR_ATR_ST	P78527	PRKDC	Q13535	ATR	S2612	L2616V	2616	Missense	distal	4	no	18.955	18.881	EPSD;PhosphoSitePlus	COSMIC	10.658	Down-regulation
Atypical_PIKK_ATR_ATR_ST	P78527	PRKDC	Q13535	ATR	S2612	M2605I	2605	Missense	distal	-7	no	18.955	18.850	EPSD;PhosphoSitePlus	COSMIC	10.658	Down-regulation
Atypical_PIKK_ATR_ATR_ST	P78527	PRKDC	Q13535	ATR	S2612	T2618I	2618	Missense	distal	6	no	18.955	18.729	EPSD;PhosphoSitePlus	COSMIC	10.658	Down-regulation
Atypical_PIKK_ATR_ATR_ST	P78527	PRKDC	Q13535	ATR	S2612	R2619H	2619	Missense	distal	7	no	18.955	18.984	EPSD;PhosphoSitePlus	COSMIC	10.658	Up-regulation
Atypical_PIKK_ATR_ATR_ST	P78527	PRKDC	Q13535	ATR	T2620	T2620N	2620	Missense	central	0	yes	14.439	0.000	EPSD	COSMIC	10.658	Loss
Atypical_PIKK_ATR_ATR_ST	P78527	PRKDC	Q13535	ATR	T2620	L2616V	2616	Missense	distal	-4	no	14.439	14.846	EPSD	COSMIC	10.658	Up-regulation
Atypical_PIKK_ATR_ATR_ST	P78527	PRKDC	Q13535	ATR	T2620	T2618I	2618	Missense	proximal	-2	no	14.439	14.634	EPSD	COSMIC	10.658	Up-regulation
Atypical_PIKK_ATR_ATR_ST	P78527	PRKDC	Q13535	ATR	T2620	R2619H	2619	Missense	proximal	-1	no	14.439	14.333	EPSD	COSMIC	10.658	Down-regulation
Atypical_PIKK_ATR_ATR_ST	P78527	PRKDC	Q13535	ATR	T2620	S2626L	2626	Missense	distal	6	no	14.439	14.215	EPSD	COSMIC	10.658	Down-regulation
Atypical_PIKK_ATR_ATR_ST	P78527	PRKDC	Q13535	ATR	T2638	R2636M	2636	Missense	proximal	-2	no	13.856	13.816	EPSD	COSMIC	10.658	Down-regulation
Atypical_PIKK_ATR_ATR_ST	P78527	PRKDC	Q13535	ATR	T2647	R2653T	2653	Missense	distal	6	no	14.045	14.395	EPSD;PhosphoSitePlus	COSMIC	10.658	Up-regulation
Atypical_PIKK_ATR_ATR_ST	P78527	PRKDC	Q13535	ATR	S2672	S2675F	2675	Missense	distal	3	no	11.048	10.017	EPSD	COSMIC	10.658	Loss
Atypical_PIKK_ATR_ATR_ST	P78527	PRKDC	Q13535	ATR	S2672	V2668G	2668	Missense	distal	-4	no	11.048	10.999	EPSD	COSMIC	10.658	Down-regulation
Atypical_PIKK_ATR_ATR_ST	P78527	PRKDC	Q13535	ATR	S2672	P2673L	2673	Missense	proximal	1	no	11.048	10.482	EPSD	COSMIC	10.658	Loss
Atypical_PIKK_ATR_ATR_ST	P78527	PRKDC	Q13535	ATR	S2695	V2696M	2696	Missense	proximal	1	no	-2.042	13.568	EPSD	COSMIC	10.658	Gain
Atypical_PIKK_ATR_ATR_ST	P78527	PRKDC	Q13535	ATR	T2953	Q2954E	2954	Missense	proximal	1	no	12.113	6.192	EPSD	COSMIC	10.658	Loss
Atypical_PIKK_ATR_ATR_ST	P78527	PRKDC	Q13535	ATR	T2953	E2960K	2960	Missense	distal	7	no	12.113	12.262	EPSD	COSMIC	10.658	Up-regulation
Atypical_PIKK_ATR_ATR_ST	P78527	PRKDC	Q13535	ATR	S2998	L3005I	3005	Missense	distal	7	no	11.068	11.226	EPSD	COSMIC	10.658	Up-regulation
Atypical_PIKK_ATR_ATR_ST	P78527	PRKDC	Q13535	ATR	S2998	N3003K	3003	Missense	distal	5	no	11.068	11.067	EPSD	COSMIC	10.658	Down-regulation
Atypical_PIKK_ATR_ATR_ST	P78527	PRKDC	Q13535	ATR	S3205	D3203N	3203	Missense	proximal	-2	no	10.587	11.043	EPSD	COSMIC	10.658	Gain
Atypical_PIKK_ATR_ATR_ST	P78527	PRKDC	Q13535	ATR	S3228	D3226N	3226	Missense	proximal	-2	no	10.297	10.754	EPSD	COSMIC	10.658	Gain
Atypical_PIKK_ATR_ATR_ST	P78527	PRKDC	Q13535	ATR	S3290	E3295Q	3295	Missense	distal	5	no	11.894	11.901	EPSD	COSMIC	10.658	Up-regulation
Atypical_PIKK_ATR_ATR_ST	P78527	PRKDC	Q13535	ATR	S3290	R3287Q	3287	Missense	distal	-3	no	11.894	11.710	EPSD	COSMIC	10.658	Down-regulation
Atypical_PIKK_ATR_ATR_ST	P78527	PRKDC	Q13535	ATR	S3290	Q3296H	3296	Missense	distal	6	no	11.894	11.701	EPSD	COSMIC	10.658	Down-regulation
Atypical_PIKK_ATR_ATR_ST	P78527	PRKDC	Q13535	ATR	S3290	C3293Y	3293	Missense	distal	3	no	11.894	11.279	EPSD	COSMIC	10.658	Down-regulation
Atypical_PIKK_ATR_ATR_ST	P78527	PRKDC	Q13535	ATR	S3290	R3289W	3289	Missense	proximal	-1	no	11.894	11.992	EPSD	COSMIC	10.658	Up-regulation
Atypical_PIKK_ATR_ATR_ST	P78527	PRKDC	Q13535	ATR	S3290	H3285Y	3285	Missense	distal	-5	no	11.894	12.101	EPSD	COSMIC	10.658	Up-regulation
Atypical_PIKK_ATR_ATR_ST	P78527	PRKDC	Q13535	ATR	S3290	S3294F	3294	Missense	distal	4	no	11.894	11.913	EPSD	COSMIC	10.658	Up-regulation
Atypical_PIKK_ATR_ATR_ST	P78527	PRKDC	Q13535	ATR	S3294	E3295Q	3295	Missense	proximal	1	no	7.431	13.351	EPSD	COSMIC	10.658	Gain
Atypical_PIKK_ATR_ATR_ST	P78527	PRKDC	Q13535	ATR	S3313	N3311S	3311	Missense	proximal	-2	no	11.310	10.461	EPSD	COSMIC	10.658	Loss
Atypical_PIKK_ATR_ATR_ST	P78527	PRKDC	Q13535	ATR	S3313	L3316S	3316	Missense	distal	3	no	11.310	11.977	EPSD	COSMIC	10.658	Up-regulation
Atypical_PIKK_ATR_ATR_ST	P78527	PRKDC	Q13535	ATR	S3313	V3312M	3312	Missense	proximal	-1	no	11.310	11.460	EPSD	COSMIC	10.658	Up-regulation
Atypical_PIKK_ATR_ATR_ST	P78527	PRKDC	Q13535	ATR	T3599	N3602H	3602	Missense	distal	3	no	10.878	11.106	EPSD	COSMIC	10.658	Up-regulation
Atypical_PIKK_ATR_ATR_ST	P78527	PRKDC	Q13535	ATR	T3599	T3599I	3599	Missense	central	0	yes	10.878	0.000	EPSD	COSMIC	10.658	Loss
Atypical_PIKK_ATR_ATR_ST	P78527	PRKDC	Q13535	ATR	T3599	P3600T	3600	Missense	proximal	1	no	10.878	6.227	EPSD	COSMIC	10.658	Loss
Atypical_PIKK_ATR_ATR_ST	P78527	PRKDC	Q13535	ATR	T3599	V3601L	3601	Missense	proximal	2	no	10.878	9.276	EPSD	COSMIC	10.658	Loss
Atypical_PIKK_ATR_ATR_ST	P78527	PRKDC	Q13535	ATR	T3811	L3815R	3815	Missense	distal	4	no	10.851	10.666	EPSD	COSMIC	10.658	Down-regulation
Atypical_PIKK_ATR_ATR_ST	P78527	PRKDC	Q13535	ATR	T3811	L3816P	3816	Missense	distal	5	no	10.851	10.856	EPSD	COSMIC	10.658	Up-regulation
Atypical_PIKK_ATR_ATR_ST	P78527	PRKDC	Q13535	ATR	T3811	E3804K	3804	Missense	distal	-7	no	10.851	10.834	EPSD	COSMIC	10.658	Down-regulation
Atypical_PIKK_ATR_ATR_ST	P78527	PRKDC	Q13535	ATR	S3821	A3826V	3826	Missense	distal	5	no	14.825	14.815	EPSD	COSMIC	10.658	Down-regulation
Atypical_PIKK_ATR_ATR_ST	P78527	PRKDC	Q13535	ATR	S3821	L3815R	3815	Missense	distal	-6	no	14.825	14.797	EPSD	COSMIC	10.658	Down-regulation
Atypical_PIKK_ATR_ATR_ST	P78527	PRKDC	Q13535	ATR	S3821	A3826T	3826	Missense	distal	5	no	14.825	14.822	EPSD	COSMIC	10.658	Down-regulation
Atypical_PIKK_ATR_ATR_ST	P78527	PRKDC	Q13535	ATR	S3821	L3816P	3816	Missense	distal	-5	no	14.825	14.672	EPSD	COSMIC	10.658	Down-regulation
Atypical_PIKK_ATR_ATR_ST	P78527	PRKDC	Q13535	ATR	S3821	S3821P	3821	Missense	central	0	yes	14.825	0.000	EPSD	COSMIC	10.658	Loss
Atypical_PIKK_ATR_ATR_ST	P78527	PRKDC	Q13535	ATR	T4102	V4104L	4104	Missense	proximal	2	no	12.871	11.269	EPSD	COSMIC	10.658	Down-regulation
Atypical_PIKK_ATR_ATR_ST	Q99708	RBBP8	Q13535	ATR	S10	S7R	7	Missense	distal	-3	no	11.057	11.594	EPSD	COSMIC	10.658	Up-regulation
Atypical_PIKK_ATR_ATR_ST	Q99708	RBBP8	Q13535	ATR	S10	S4L	4	Missense	distal	-6	no	11.057	11.167	EPSD	COSMIC;GDSC;CCLE	10.658	Up-regulation
Atypical_PIKK_ATR_ATR_ST	Q99708	RBBP8	Q13535	ATR	T16	L23I	23	Missense	distal	7	no	10.727	10.885	EPSD	COSMIC	10.658	Up-regulation
Atypical_PIKK_ATR_ATR_ST	Q99708	RBBP8	Q13535	ATR	T16	K21N	21	Missense	distal	5	no	10.727	10.728	EPSD	COSMIC	10.658	Up-regulation
Atypical_PIKK_ATR_ATR_ST	Q99708	RBBP8	Q13535	ATR	T271	S276N	276	Missense	distal	5	no	13.320	13.325	EPSD	COSMIC	10.658	Up-regulation
Atypical_PIKK_ATR_ATR_ST	Q99708	RBBP8	Q13535	ATR	S439	P436S	436	Missense	distal	-3	no	13.000	12.724	EPSD	COSMIC;GDSC;CCLE	10.658	Down-regulation
Atypical_PIKK_ATR_ATR_ST	Q99708	RBBP8	Q13535	ATR	S439	G441E	441	Missense	proximal	2	no	13.000	13.130	EPSD	COSMIC;GDSC;CCLE	10.658	Up-regulation
Atypical_PIKK_ATR_ATR_ST	Q99708	RBBP8	Q13535	ATR	S555	E552Q	552	Missense	distal	-3	no	15.106	15.258	EPSD	COSMIC	10.658	Up-regulation
Atypical_PIKK_ATR_ATR_ST	Q99708	RBBP8	Q13535	ATR	S555	E552D	552	Missense	distal	-3	no	15.106	15.699	EPSD	COSMIC	10.658	Up-regulation
Atypical_PIKK_ATR_ATR_ST	Q99708	RBBP8	Q13535	ATR	S593	R589H	589	Missense	distal	-4	no	11.000	11.001	EPSD	COSMIC	10.658	Up-regulation
Atypical_PIKK_ATR_ATR_ST	Q99708	RBBP8	Q13535	ATR	S593	R591H	591	Missense	proximal	-2	no	11.000	10.554	EPSD	COSMIC	10.658	Loss
Atypical_PIKK_ATR_ATR_ST	Q99708	RBBP8	Q13535	ATR	T596	R589H	589	Missense	distal	-7	no	11.187	11.238	EPSD	COSMIC	10.658	Up-regulation
Atypical_PIKK_ATR_ATR_ST	Q99708	RBBP8	Q13535	ATR	T596	R591H	591	Missense	distal	-5	no	11.187	11.125	EPSD	COSMIC	10.658	Down-regulation
Atypical_PIKK_ATR_ATR_ST	Q99708	RBBP8	Q13535	ATR	S664	D662H	662	Missense	proximal	-2	no	11.369	10.941	EPSD	COSMIC	10.658	Down-regulation
Atypical_PIKK_ATR_ATR_ST	Q99708	RBBP8	Q13535	ATR	S745	D742N	742	Missense	distal	-3	no	12.813	13.105	EPSD	COSMIC	10.658	Up-regulation
Atypical_PIKK_ATR_ATR_ST	Q99708	RBBP8	Q13535	ATR	S745	S745C	745	Missense	central	0	yes	12.813	0.000	EPSD	COSMIC	10.658	Loss
Atypical_PIKK_ATR_ATR_ST	Q99708	RBBP8	Q13535	ATR	S789	S789C	789	Missense	central	0	yes	12.054	0.000	EPSD	COSMIC	10.658	Loss
Atypical_PIKK_ATR_ATR_ST	Q99708	RBBP8	Q13535	ATR	S789	P794S	794	Missense	distal	5	no	12.054	12.042	EPSD	COSMIC	10.658	Down-regulation
Atypical_PIKK_ATR_ATR_ST	Q9UPV0	CEP164	Q13535	ATR	S186	M183I	183	Missense	distal	-3	no	16.460	16.468	PhosphoSitePlus	COSMIC	10.658	Up-regulation
Atypical_PIKK_ATR_ATR_ST	Q9UPV0	CEP164	Q13535	ATR	S234	H232Q	232	Missense	proximal	-2	no	11.289	11.656	EPSD	COSMIC;GDSC;CCLE	10.658	Up-regulation
Atypical_PIKK_ATR_ATR_ST	Q9UPV0	CEP164	Q13535	ATR	S273	T280S	280	Missense	distal	7	no	12.782	12.611	EPSD	COSMIC	10.658	Down-regulation
Atypical_PIKK_ATR_ATR_ST	Q9UPV0	CEP164	Q13535	ATR	S286	K283N	283	Missense	distal	-3	no	9.585	10.745	EPSD	COSMIC;GDSC;CCLE	10.658	Gain
Atypical_PIKK_ATR_ATR_ST	Q9UPV0	CEP164	Q13535	ATR	S319	C324F	324	Missense	distal	5	no	10.968	10.954	EPSD	COSMIC	10.658	Down-regulation
Atypical_PIKK_ATR_ATR_ST	Q9UPV0	CEP164	Q13535	ATR	S472	G466D	466	Missense	distal	-6	no	13.499	13.532	EPSD	COSMIC	10.658	Up-regulation
Atypical_PIKK_ATR_ATR_ST	Q9UPV0	CEP164	Q13535	ATR	S472	H477Y	477	Missense	distal	5	no	13.499	13.515	EPSD	COSMIC	10.658	Up-regulation
Atypical_PIKK_ATR_ATR_ST	Q9UPV0	CEP164	Q13535	ATR	S472	P476S	476	Missense	distal	4	no	13.499	13.412	EPSD	COSMIC	10.658	Down-regulation
Atypical_PIKK_ATR_ATR_ST	Q9UPV0	CEP164	Q13535	ATR	S531	A529S	529	Missense	proximal	-2	no	11.636	10.860	EPSD	COSMIC	10.658	Down-regulation
Atypical_PIKK_ATR_ATR_ST	Q9UPV0	CEP164	Q13535	ATR	S531	S531R	531	Missense	central	0	yes	11.636	0.000	EPSD	COSMIC	10.658	Loss
Atypical_PIKK_ATR_ATR_ST	Q9UPV0	CEP164	Q13535	ATR	S531	P530S	530	Missense	proximal	-1	no	11.636	11.421	EPSD	COSMIC	10.658	Down-regulation
Atypical_PIKK_ATR_ATR_ST	Q9UPV0	CEP164	Q13535	ATR	S531	P532S	532	Missense	proximal	1	no	11.636	10.526	EPSD	COSMIC	10.658	Loss
Atypical_PIKK_ATR_ATR_ST	Q9UPV0	CEP164	Q13535	ATR	S531	A534V	534	Missense	distal	3	no	11.636	12.396	EPSD	COSMIC	10.658	Up-regulation
Atypical_PIKK_ATR_ATR_ST	Q9UPV0	CEP164	Q13535	ATR	S531	Q528R	528	Missense	distal	-3	no	11.636	11.820	EPSD	COSMIC	10.658	Up-regulation
Atypical_PIKK_ATR_ATR_ST	Q9UPV0	CEP164	Q13535	ATR	S566	T568P	568	Missense	proximal	2	no	10.902	11.609	EPSD	COSMIC	10.658	Up-regulation
Atypical_PIKK_ATR_ATR_ST	Q9UPV0	CEP164	Q13535	ATR	S566	A564E	564	Missense	proximal	-2	no	10.902	10.422	EPSD	COSMIC	10.658	Loss
Atypical_PIKK_ATR_ATR_ST	Q9UPV0	CEP164	Q13535	ATR	S572	T568P	568	Missense	distal	-4	no	10.740	11.152	EPSD	COSMIC	10.658	Up-regulation
Atypical_PIKK_ATR_ATR_ST	Q9UPV0	CEP164	Q13535	ATR	S572	S566T	566	Missense	distal	-6	no	10.740	10.826	EPSD	COSMIC;GDSC	10.658	Up-regulation
Atypical_PIKK_ATR_ATR_ST	Q9UPV0	CEP164	Q13535	ATR	S645	L647V	647	Missense	proximal	2	no	10.035	11.637	EPSD	COSMIC	10.658	Gain
Atypical_PIKK_ATR_ATR_ST	Q9UPV0	CEP164	Q13535	ATR	S646	L647V	647	Missense	proximal	1	no	11.262	-2.999	EPSD	COSMIC	10.658	Loss
Atypical_PIKK_ATR_ATR_ST	Q9UPV0	CEP164	Q13535	ATR	S1013	R1007C	1007	Missense	distal	-6	no	11.284	11.271	EPSD	COSMIC	10.658	Down-regulation
Atypical_PIKK_ATR_ATR_ST	Q9UPV0	CEP164	Q13535	ATR	S1273	I1271T	1271	Missense	proximal	-2	no	12.654	12.459	EPSD	COSMIC	10.658	Down-regulation
Atypical_PIKK_ATR_ATR_ST	Q9UPV0	CEP164	Q13535	ATR	S1273	R1269Q	1269	Missense	distal	-4	no	12.654	12.836	EPSD	COSMIC	10.658	Up-regulation
Atypical_PIKK_ATR_ATR_ST	Q9UPV0	CEP164	Q13535	ATR	S1273	R1269W	1269	Missense	distal	-4	no	12.654	13.112	EPSD	COSMIC	10.658	Up-regulation
Atypical_PIKK_ATR_ATR_ST	Q9UPV0	CEP164	Q13535	ATR	S1273	S1280R	1280	Missense	distal	7	no	12.654	12.878	EPSD	COSMIC	10.658	Up-regulation
Atypical_PIKK_ATR_ATR_ST	Q9UPV0	CEP164	Q13535	ATR	S1273	S1273N	1273	Missense	central	0	yes	12.654	0.000	EPSD	COSMIC	10.658	Loss
Atypical_PIKK_ATR_ATR_ST	Q9UPV0	CEP164	Q13535	ATR	T1441	L1445M	1445	Missense	distal	4	no	11.043	10.362	EPSD	COSMIC	10.658	Loss
Atypical_PIKK_ATR_ATR_ST	Q9UPV0	CEP164	Q13535	ATR	S1443	L1445M	1445	Missense	proximal	2	no	11.513	12.885	EPSD	COSMIC	10.658	Up-regulation
Atypical_PIKK_ATR_ATR_ST	Q8WXE1	ATRIP	Q13535	ATR	S13	R19L	19	Missense	distal	6	no	10.540	10.712	EPSD	COSMIC	10.658	Gain
Atypical_PIKK_ATR_ATR_ST	Q8WXE1	ATRIP	Q13535	ATR	S13	R19Q	19	Missense	distal	6	no	10.540	10.808	EPSD	COSMIC	10.658	Gain
Atypical_PIKK_ATR_ATR_ST	Q8WXE1	ATRIP	Q13535	ATR	S68	D64Y	64	Missense	distal	-4	no	16.399	13.171	PhosphoSitePlus;EPSD	COSMIC	10.658	Down-regulation
Atypical_PIKK_ATR_ATR_ST	Q8WXE1	ATRIP	Q13535	ATR	S68	A70V	70	Missense	proximal	2	no	16.399	16.888	PhosphoSitePlus;EPSD	COSMIC	10.658	Up-regulation
Atypical_PIKK_ATR_ATR_ST	Q8WXE1	ATRIP	Q13535	ATR	S72	R79W	79	Missense	distal	7	no	15.127	15.186	EPSD;PhosphoSitePlus	COSMIC	10.658	Up-regulation
Atypical_PIKK_ATR_ATR_ST	Q8WXE1	ATRIP	Q13535	ATR	S72	A70V	70	Missense	proximal	-2	no	15.127	14.607	EPSD;PhosphoSitePlus	COSMIC	10.658	Down-regulation
Atypical_PIKK_ATR_ATR_ST	P42771	CDKN2A	Q13535	ATR	S7	D14E	14	Missense	distal	7	no	13.128	12.933	EPSD;PhosphoSitePlus	COSMIC	10.658	Down-regulation
Atypical_PIKK_ATR_ATR_ST	P42771	CDKN2A	Q13535	ATR	S7	A13D	13	Missense	distal	6	no	13.128	13.264	EPSD;PhosphoSitePlus	COSMIC	10.658	Up-regulation
Atypical_PIKK_ATR_ATR_ST	P42771	CDKN2A	Q13535	ATR	S7	G6W	6	Missense	proximal	-1	no	13.128	13.259	EPSD;PhosphoSitePlus	COSMIC	10.658	Up-regulation
Atypical_PIKK_ATR_ATR_ST	P42771	CDKN2A	Q13535	ATR	S7	D14N	14	Missense	distal	7	no	13.128	13.352	EPSD;PhosphoSitePlus	COSMIC	10.658	Up-regulation
Atypical_PIKK_ATR_ATR_ST	P42771	CDKN2A	Q13535	ATR	S7	A5T	5	Missense	proximal	-2	no	13.128	12.654	EPSD;PhosphoSitePlus	COSMIC	10.658	Down-regulation
Atypical_PIKK_ATR_ATR_ST	P42771	CDKN2A	Q13535	ATR	S7	S7R	7	Missense	central	0	yes	13.128	0.000	EPSD;PhosphoSitePlus	COSMIC	10.658	Loss
Atypical_PIKK_ATR_ATR_ST	P42771	CDKN2A	Q13535	ATR	S7	E2K	2	Missense	distal	-5	no	13.128	13.209	EPSD;PhosphoSitePlus	COSMIC	10.658	Up-regulation
Atypical_PIKK_ATR_ATR_ST	P42771	CDKN2A	Q13535	ATR	S7	M9I	9	Missense	proximal	2	no	13.128	12.048	EPSD;PhosphoSitePlus	COSMIC	10.658	Down-regulation
Atypical_PIKK_ATR_ATR_ST	P42771	CDKN2A	Q13535	ATR	S7	E10V	10	Missense	distal	3	no	13.128	13.542	EPSD;PhosphoSitePlus	COSMIC	10.658	Up-regulation
Atypical_PIKK_ATR_ATR_ST	P42771	CDKN2A	Q13535	ATR	S7	P11S	11	Missense	distal	4	no	13.128	13.041	EPSD;PhosphoSitePlus	COSMIC	10.658	Down-regulation
Atypical_PIKK_ATR_ATR_ST	P42771	CDKN2A	Q13535	ATR	S7	D14V	14	Missense	distal	7	no	13.128	13.181	EPSD;PhosphoSitePlus	COSMIC	10.658	Up-regulation
Atypical_PIKK_ATR_ATR_ST	P42771	CDKN2A	Q13535	ATR	S7	A4T	4	Missense	distal	-3	no	13.128	12.566	EPSD;PhosphoSitePlus	COSMIC	10.658	Down-regulation
Atypical_PIKK_ATR_ATR_ST	P42771	CDKN2A	Q13535	ATR	S7	A4S	4	Missense	distal	-3	no	13.128	12.288	EPSD;PhosphoSitePlus	COSMIC	10.658	Down-regulation
Atypical_PIKK_ATR_ATR_ST	P42771	CDKN2A	Q13535	ATR	S7	S7C	7	Missense	central	0	yes	13.128	0.000	EPSD;PhosphoSitePlus	COSMIC	10.658	Loss
Atypical_PIKK_ATR_ATR_ST	P42771	CDKN2A	Q13535	ATR	S7	E10G	10	Missense	distal	3	no	13.128	12.948	EPSD;PhosphoSitePlus	COSMIC	10.658	Down-regulation
Atypical_PIKK_ATR_ATR_ST	P42771	CDKN2A	Q13535	ATR	S7	G6E	6	Missense	proximal	-1	no	13.128	13.176	EPSD;PhosphoSitePlus	COSMIC	10.658	Up-regulation
Atypical_PIKK_ATR_ATR_ST	P42771	CDKN2A	Q13535	ATR	S8	D14E	14	Missense	distal	6	no	14.293	14.568	EPSD;PhosphoSitePlus	COSMIC	10.658	Up-regulation
Atypical_PIKK_ATR_ATR_ST	P42771	CDKN2A	Q13535	ATR	S8	A13D	13	Missense	distal	5	no	14.293	14.292	EPSD;PhosphoSitePlus	COSMIC	10.658	Down-regulation
Atypical_PIKK_ATR_ATR_ST	P42771	CDKN2A	Q13535	ATR	S8	G6W	6	Missense	proximal	-2	no	14.293	14.496	EPSD;PhosphoSitePlus	COSMIC	10.658	Up-regulation
Atypical_PIKK_ATR_ATR_ST	P42771	CDKN2A	Q13535	ATR	S8	D14N	14	Missense	distal	6	no	14.293	14.597	EPSD;PhosphoSitePlus	COSMIC	10.658	Up-regulation
Atypical_PIKK_ATR_ATR_ST	P42771	CDKN2A	Q13535	ATR	S8	A5T	5	Missense	distal	-3	no	14.293	13.732	EPSD;PhosphoSitePlus	COSMIC	10.658	Down-regulation
Atypical_PIKK_ATR_ATR_ST	P42771	CDKN2A	Q13535	ATR	S8	W15L	15	Missense	distal	7	no	14.293	14.172	EPSD;PhosphoSitePlus	COSMIC	10.658	Down-regulation
Atypical_PIKK_ATR_ATR_ST	P42771	CDKN2A	Q13535	ATR	S8	S7R	7	Missense	proximal	-1	no	14.293	14.421	EPSD;PhosphoSitePlus	COSMIC	10.658	Up-regulation
Atypical_PIKK_ATR_ATR_ST	P42771	CDKN2A	Q13535	ATR	S8	E2K	2	Missense	distal	-6	no	14.293	14.246	EPSD;PhosphoSitePlus	COSMIC	10.658	Down-regulation
Atypical_PIKK_ATR_ATR_ST	P42771	CDKN2A	Q13535	ATR	S8	M9I	9	Missense	proximal	1	no	14.293	10.889	EPSD;PhosphoSitePlus	COSMIC	10.658	Down-regulation
Atypical_PIKK_ATR_ATR_ST	P42771	CDKN2A	Q13535	ATR	S8	E10V	10	Missense	proximal	2	no	14.293	13.862	EPSD;PhosphoSitePlus	COSMIC	10.658	Down-regulation
Atypical_PIKK_ATR_ATR_ST	P42771	CDKN2A	Q13535	ATR	S8	P11S	11	Missense	distal	3	no	14.293	14.357	EPSD;PhosphoSitePlus	COSMIC	10.658	Up-regulation
Atypical_PIKK_ATR_ATR_ST	P42771	CDKN2A	Q13535	ATR	S8	D14V	14	Missense	distal	6	no	14.293	14.370	EPSD;PhosphoSitePlus	COSMIC	10.658	Up-regulation
Atypical_PIKK_ATR_ATR_ST	P42771	CDKN2A	Q13535	ATR	S8	A4T	4	Missense	distal	-4	no	14.293	13.686	EPSD;PhosphoSitePlus	COSMIC	10.658	Down-regulation
Atypical_PIKK_ATR_ATR_ST	P42771	CDKN2A	Q13535	ATR	S8	A4S	4	Missense	distal	-4	no	14.293	13.773	EPSD;PhosphoSitePlus	COSMIC	10.658	Down-regulation
Atypical_PIKK_ATR_ATR_ST	P42771	CDKN2A	Q13535	ATR	S8	S7C	7	Missense	proximal	-1	no	14.293	14.845	EPSD;PhosphoSitePlus	COSMIC	10.658	Up-regulation
Atypical_PIKK_ATR_ATR_ST	P42771	CDKN2A	Q13535	ATR	S8	E10G	10	Missense	proximal	2	no	14.293	14.164	EPSD;PhosphoSitePlus	COSMIC	10.658	Down-regulation
Atypical_PIKK_ATR_ATR_ST	P42771	CDKN2A	Q13535	ATR	S8	G6E	6	Missense	proximal	-2	no	14.293	14.277	EPSD;PhosphoSitePlus	COSMIC	10.658	Down-regulation
Atypical_PIKK_ATR_ATR_ST	P23508	MCC	Q13535	ATR	S120	S118N	118	Missense	proximal	-2	no	15.800	16.649	PhosphoSitePlus;EPSD	COSMIC	10.658	Up-regulation
Atypical_PIKK_ATR_ATR_ST	P23508	MCC	Q13535	ATR	S179	V173F	173	Missense	distal	-6	no	12.201	12.203	EPSD	COSMIC	10.658	Up-regulation
Atypical_PIKK_ATR_ATR_ST	P23508	MCC	Q13535	ATR	S179	S182T	182	Missense	distal	3	no	12.201	11.852	EPSD	COSMIC	10.658	Down-regulation
Atypical_PIKK_ATR_ATR_ST	P23508	MCC	Q13535	ATR	S179	G175S	175	Missense	distal	-4	no	12.201	12.718	EPSD	COSMIC	10.658	Up-regulation
Atypical_PIKK_ATR_ATR_ST	P23508	MCC	Q13535	ATR	S294	P292L	292	Missense	proximal	-2	no	10.011	10.662	EPSD	COSMIC	10.658	Gain
Atypical_PIKK_ATR_ATR_ST	P23508	MCC	Q13535	ATR	S315	P322S	322	Missense	distal	7	no	11.613	11.449	EPSD	COSMIC	10.658	Down-regulation
Atypical_PIKK_ATR_ATR_ST	P23508	MCC	Q13535	ATR	S315	G310V	310	Missense	distal	-5	no	11.613	11.695	EPSD	COSMIC	10.658	Up-regulation
Atypical_PIKK_ATR_ATR_ST	P23508	MCC	Q13535	ATR	S315	L312P	312	Missense	distal	-3	no	11.613	11.318	EPSD	COSMIC	10.658	Down-regulation
Atypical_PIKK_ATR_ATR_ST	P23508	MCC	Q13535	ATR	S315	S315I	315	Missense	central	0	yes	11.613	0.000	EPSD	COSMIC	10.658	Loss
Atypical_PIKK_ATR_ATR_ST	P23508	MCC	Q13535	ATR	S315	S308N	308	Missense	distal	-7	no	11.613	11.479	EPSD	COSMIC	10.658	Down-regulation
Atypical_PIKK_ATR_ATR_ST	P23508	MCC	Q13535	ATR	S412	R406W	406	Missense	distal	-6	no	15.876	15.888	EPSD	COSMIC	10.658	Up-regulation
Atypical_PIKK_ATR_ATR_ST	P23508	MCC	Q13535	ATR	S426	A428V	428	Missense	proximal	2	no	11.528	12.018	EPSD	COSMIC	10.658	Up-regulation
Atypical_PIKK_ATR_ATR_ST	P23508	MCC	Q13535	ATR	S426	E422D	422	Missense	distal	-4	no	11.528	11.346	EPSD	COSMIC	10.658	Down-regulation
Atypical_PIKK_ATR_ATR_ST	P23508	MCC	Q13535	ATR	S432	E439K	439	Missense	distal	7	no	10.528	10.677	EPSD	COSMIC	10.658	Gain
Atypical_PIKK_ATR_ATR_ST	P23508	MCC	Q13535	ATR	S432	Y438C	438	Missense	distal	6	no	10.528	10.840	EPSD	COSMIC	10.658	Gain
Atypical_PIKK_ATR_ATR_ST	P23508	MCC	Q13535	ATR	T496	K500N	500	Missense	distal	4	no	14.736	15.505	EPSD	COSMIC	10.658	Up-regulation
Atypical_PIKK_ATR_ATR_ST	P23508	MCC	Q13535	ATR	T496	T496N	496	Missense	central	0	yes	14.736	0.000	EPSD	COSMIC	10.658	Loss
Atypical_PIKK_ATR_ATR_ST	P23508	MCC	Q13535	ATR	T496	S490F	490	Missense	distal	-6	no	14.736	14.816	EPSD	COSMIC;CCLE	10.658	Up-regulation
Atypical_PIKK_ATR_ATR_ST	P23508	MCC	Q13535	ATR	S702	S706C	706	Missense	distal	4	no	14.939	15.628	EPSD	COSMIC	10.658	Up-regulation
Atypical_PIKK_ATR_ATR_ST	P23508	MCC	Q13535	ATR	S702	E696K	696	Missense	distal	-6	no	14.939	14.892	EPSD	COSMIC	10.658	Down-regulation
Atypical_PIKK_ATR_ATR_ST	P23508	MCC	Q13535	ATR	S702	D699H	699	Missense	distal	-3	no	14.939	14.315	EPSD	COSMIC	10.658	Down-regulation
Atypical_PIKK_ATR_ATR_ST	P23508	MCC	Q13535	ATR	S770	R767Q	767	Missense	distal	-3	no	10.964	10.780	EPSD	COSMIC	10.658	Down-regulation
Atypical_PIKK_ATR_ATR_ST	P23508	MCC	Q13535	ATR	S792	S792L	792	Missense	central	0	yes	12.484	0.000	EPSD	COSMIC	10.658	Loss
Atypical_PIKK_ATR_ATR_ST	P23508	MCC	Q13535	ATR	S792	A796V	796	Missense	distal	4	no	12.484	12.345	EPSD	COSMIC	10.658	Down-regulation
Atypical_PIKK_ATR_ATR_ST	P23508	MCC	Q13535	ATR	S792	M795I	795	Missense	distal	3	no	12.484	13.184	EPSD	COSMIC	10.658	Up-regulation
Atypical_PIKK_ATR_ATR_ST	P23508	MCC	Q13535	ATR	T803	L808P	808	Missense	distal	5	no	15.892	15.896	EPSD	COSMIC	10.658	Up-regulation
Atypical_PIKK_ATR_ATR_ST	P23508	MCC	Q13535	ATR	T803	Q810K	810	Missense	distal	7	no	15.892	15.981	EPSD	COSMIC	10.658	Up-regulation
Atypical_PIKK_ATR_ATR_ST	P23508	MCC	Q13535	ATR	T803	E802D	802	Missense	proximal	-1	no	15.892	15.937	EPSD	COSMIC	10.658	Up-regulation
Atypical_PIKK_ATR_ATR_ST	P23508	MCC	Q13535	ATR	T803	A796V	796	Missense	distal	-7	no	15.892	15.871	EPSD	COSMIC	10.658	Down-regulation
Atypical_PIKK_ATR_ATR_ST	O14757	CHEK1	Q13535	ATR	S296	F300L	300	Missense	distal	4	no	15.413	15.631	PhosphoSitePlus;EPSD	COSMIC	10.658	Up-regulation
Atypical_PIKK_ATR_ATR_ST	O14757	CHEK1	Q13535	ATR	S296	P302A	302	Missense	distal	6	no	15.413	15.384	PhosphoSitePlus;EPSD	COSMIC	10.658	Down-regulation
Atypical_PIKK_ATR_ATR_ST	O14757	CHEK1	Q13535	ATR	S317	P321L	321	Missense	distal	4	no	17.676	17.826	EPSD;PhosphoSitePlus	COSMIC	10.658	Up-regulation
Atypical_PIKK_ATR_ATR_ST	O14757	CHEK1	Q13535	ATR	S317	P321T	321	Missense	distal	4	no	17.676	17.641	EPSD;PhosphoSitePlus	COSMIC	10.658	Down-regulation
Atypical_PIKK_ATR_ATR_ST	O14757	CHEK1	Q13535	ATR	S317	R322C	322	Missense	distal	5	no	17.676	17.691	EPSD;PhosphoSitePlus	COSMIC	10.658	Up-regulation
Atypical_PIKK_ATR_ATR_ST	O14757	CHEK1	Q13535	ATR	S317	V312M	312	Missense	distal	-5	no	17.676	17.475	EPSD;PhosphoSitePlus	COSMIC;CCLE	10.658	Down-regulation
Atypical_PIKK_ATR_ATR_ST	O14757	CHEK1	Q13535	ATR	S317	E320K	320	Missense	distal	3	no	17.676	17.833	EPSD;PhosphoSitePlus	COSMIC	10.658	Up-regulation
Atypical_PIKK_ATR_ATR_ST	O14757	CHEK1	Q13535	ATR	S345	G341R	341	Missense	distal	-4	no	17.127	17.346	EPSD;PhosphoSitePlus	COSMIC	10.658	Up-regulation
Atypical_PIKK_ATR_ATR_ST	O14757	CHEK1	Q13535	ATR	S345	F344L	344	Missense	proximal	-1	no	17.127	17.361	EPSD;PhosphoSitePlus	COSMIC	10.658	Up-regulation
Atypical_PIKK_ATR_ATR_ST	O14757	CHEK1	Q13535	ATR	S345	H352Y	352	Missense	distal	7	no	17.127	17.059	EPSD;PhosphoSitePlus	COSMIC	10.658	Down-regulation
Atypical_PIKK_ATR_ATR_ST	O14757	CHEK1	Q13535	ATR	S357	L360F	360	Missense	distal	3	no	14.888	14.524	EPSD	COSMIC	10.658	Down-regulation
Atypical_PIKK_ATR_ATR_ST	O14757	CHEK1	Q13535	ATR	S357	H352Y	352	Missense	distal	-5	no	14.888	15.096	EPSD	COSMIC	10.658	Up-regulation
Atypical_PIKK_ATR_ATR_ST	O14757	CHEK1	Q13535	ATR	S357	G361D	361	Missense	distal	4	no	14.888	14.067	EPSD	COSMIC;GDSC;CCLE	10.658	Down-regulation
Atypical_PIKK_ATR_ATR_ST	O14757	CHEK1	Q13535	ATR	S357	L354S	354	Missense	distal	-3	no	14.888	14.317	EPSD	COSMIC	10.658	Down-regulation
Atypical_PIKK_ATR_ATR_ST	O14757	CHEK1	Q13535	ATR	S366	L360F	360	Missense	distal	-6	no	15.551	15.521	EPSD	COSMIC	10.658	Down-regulation
Atypical_PIKK_ATR_ATR_ST	O14757	CHEK1	Q13535	ATR	S366	R372W	372	Missense	distal	6	no	15.551	15.650	EPSD	COSMIC	10.658	Up-regulation
Atypical_PIKK_ATR_ATR_ST	O14757	CHEK1	Q13535	ATR	S366	G361D	361	Missense	distal	-5	no	15.551	15.703	EPSD	COSMIC;GDSC;CCLE	10.658	Up-regulation
Atypical_PIKK_ATR_ATR_ST	O14757	CHEK1	Q13535	ATR	S468	D464N	464	Missense	distal	-4	no	10.983	10.373	EPSD	COSMIC	10.658	Loss
Atypical_PIKK_ATR_ATR_ST	O14757	CHEK1	Q13535	ATR	S468	K461N	461	Missense	distal	-7	no	10.983	10.836	EPSD	COSMIC	10.658	Down-regulation
Atypical_PIKK_ATR_ATR_ST	Q12888	TP53BP1	Q13535	ATR	S105	V107A	107	Missense	proximal	2	no	12.551	12.062	EPSD	COSMIC	10.658	Down-regulation
Atypical_PIKK_ATR_ATR_ST	Q12888	TP53BP1	Q13535	ATR	S166	A160V	160	Missense	distal	-6	no	13.009	12.978	EPSD;PhosphoSitePlus	COSMIC	10.658	Down-regulation
Atypical_PIKK_ATR_ATR_ST	Q12888	TP53BP1	Q13535	ATR	T302	F307V	307	Missense	distal	5	no	16.265	16.255	PhosphoSitePlus;EPSD	COSMIC	10.658	Down-regulation
Atypical_PIKK_ATR_ATR_ST	Q12888	TP53BP1	Q13535	ATR	T302	F307L	307	Missense	distal	5	no	16.265	16.260	PhosphoSitePlus;EPSD	COSMIC	10.658	Down-regulation
Atypical_PIKK_ATR_ATR_ST	Q12888	TP53BP1	Q13535	ATR	S398	E400K	400	Missense	proximal	2	no	11.585	10.636	EPSD	COSMIC	10.658	Loss
Atypical_PIKK_ATR_ATR_ST	Q12888	TP53BP1	Q13535	ATR	S398	M392I	392	Missense	distal	-6	no	11.585	11.604	EPSD	COSMIC	10.658	Up-regulation
Atypical_PIKK_ATR_ATR_ST	Q12888	TP53BP1	Q13535	ATR	S523	T519A	519	Missense	distal	-4	no	14.431	15.038	EPSD	COSMIC	10.658	Up-regulation
Atypical_PIKK_ATR_ATR_ST	Q12888	TP53BP1	Q13535	ATR	S525	T519A	519	Missense	distal	-6	no	10.956	10.978	EPSD	COSMIC	10.658	Up-regulation
Atypical_PIKK_ATR_ATR_ST	Q12888	TP53BP1	Q13535	ATR	T543	T548A	548	Missense	distal	5	no	14.275	14.278	EPSD	COSMIC	10.658	Up-regulation
Atypical_PIKK_ATR_ATR_ST	Q12888	TP53BP1	Q13535	ATR	S625	D622N	622	Missense	distal	-3	no	13.226	13.518	EPSD	COSMIC	10.658	Up-regulation
Atypical_PIKK_ATR_ATR_ST	Q12888	TP53BP1	Q13535	ATR	S625	S623L	623	Missense	proximal	-2	no	13.226	13.928	EPSD	COSMIC	10.658	Up-regulation
Atypical_PIKK_ATR_ATR_ST	Q12888	TP53BP1	Q13535	ATR	S784	D783N	783	Missense	proximal	-1	no	12.434	12.725	EPSD	COSMIC	10.658	Up-regulation
Atypical_PIKK_ATR_ATR_ST	Q12888	TP53BP1	Q13535	ATR	S784	D789N	789	Missense	distal	5	no	12.434	12.430	EPSD	COSMIC	10.658	Down-regulation
Atypical_PIKK_ATR_ATR_ST	Q12888	TP53BP1	Q13535	ATR	S831	D829E	829	Missense	proximal	-2	no	14.534	14.438	EPSD;PhosphoSitePlus	COSMIC	10.658	Down-regulation
Atypical_PIKK_ATR_ATR_ST	Q12888	TP53BP1	Q13535	ATR	S831	S830F	830	Missense	proximal	-1	no	14.534	14.536	EPSD;PhosphoSitePlus	COSMIC	10.658	Up-regulation
Atypical_PIKK_ATR_ATR_ST	Q12888	TP53BP1	Q13535	ATR	S892	S899R	899	Missense	distal	7	no	13.351	13.575	EPSD	COSMIC	10.658	Up-regulation
Atypical_PIKK_ATR_ATR_ST	Q12888	TP53BP1	Q13535	ATR	S892	S888A	888	Missense	distal	-4	no	13.351	13.872	EPSD	COSMIC	10.658	Up-regulation
Atypical_PIKK_ATR_ATR_ST	Q12888	TP53BP1	Q13535	ATR	S892	S894R	894	Missense	proximal	2	no	13.351	13.077	EPSD	COSMIC	10.658	Down-regulation
Atypical_PIKK_ATR_ATR_ST	Q12888	TP53BP1	Q13535	ATR	T1032	S1028I	1028	Missense	distal	-4	no	13.199	11.857	EPSD	COSMIC	10.658	Down-regulation
Atypical_PIKK_ATR_ATR_ST	Q12888	TP53BP1	Q13535	ATR	T1032	V1026A	1026	Missense	distal	-6	no	13.199	13.230	EPSD	COSMIC	10.658	Up-regulation
Atypical_PIKK_ATR_ATR_ST	Q12888	TP53BP1	Q13535	ATR	T1032	A1027G	1027	Missense	distal	-5	no	13.199	13.119	EPSD	COSMIC	10.658	Down-regulation
Atypical_PIKK_ATR_ATR_ST	Q12888	TP53BP1	Q13535	ATR	S1068	S1068F	1068	Missense	central	0	yes	15.675	0.000	EPSD	COSMIC	10.658	Loss
Atypical_PIKK_ATR_ATR_ST	Q12888	TP53BP1	Q13535	ATR	S1068	F1065I	1065	Missense	distal	-3	no	15.675	14.839	EPSD	COSMIC	10.658	Down-regulation
Atypical_PIKK_ATR_ATR_ST	Q12888	TP53BP1	Q13535	ATR	S1086	P1089L	1089	Missense	distal	3	no	11.939	11.335	EPSD	COSMIC	10.658	Down-regulation
Atypical_PIKK_ATR_ATR_ST	Q12888	TP53BP1	Q13535	ATR	S1104	S1101F	1101	Missense	distal	-3	no	15.441	16.300	EPSD	COSMIC	10.658	Up-regulation
Atypical_PIKK_ATR_ATR_ST	Q12888	TP53BP1	Q13535	ATR	S1148	K1141Q	1141	Missense	distal	-7	no	14.705	14.677	EPSD	COSMIC	10.658	Down-regulation
Atypical_PIKK_ATR_ATR_ST	Q12888	TP53BP1	Q13535	ATR	T1171	T1173S	1173	Missense	proximal	2	no	14.432	14.823	EPSD	COSMIC	10.658	Up-regulation
Atypical_PIKK_ATR_ATR_ST	Q12888	TP53BP1	Q13535	ATR	T1270	E1271Q	1271	Missense	proximal	1	no	4.951	10.872	EPSD	COSMIC	10.658	Gain
Atypical_PIKK_ATR_ATR_ST	Q12888	TP53BP1	Q13535	ATR	S1290	T1285S	1285	Missense	distal	-5	no	13.072	13.060	EPSD	COSMIC	10.658	Down-regulation
Atypical_PIKK_ATR_ATR_ST	Q12888	TP53BP1	Q13535	ATR	S1290	Q1291E	1291	Missense	proximal	1	no	13.072	7.151	EPSD	COSMIC	10.658	Loss
Atypical_PIKK_ATR_ATR_ST	Q12888	TP53BP1	Q13535	ATR	S1304	S1307F	1307	Missense	distal	3	no	12.642	11.611	EPSD	COSMIC	10.658	Down-regulation
Atypical_PIKK_ATR_ATR_ST	Q12888	TP53BP1	Q13535	ATR	S1304	D1298N	1298	Missense	distal	-6	no	12.642	12.645	EPSD	COSMIC	10.658	Up-regulation
Atypical_PIKK_ATR_ATR_ST	Q12888	TP53BP1	Q13535	ATR	S1368	G1371R	1371	Missense	distal	3	no	16.115	16.173	EPSD	COSMIC	10.658	Up-regulation
Atypical_PIKK_ATR_ATR_ST	Q12888	TP53BP1	Q13535	ATR	S1460	R1458H	1458	Missense	proximal	-2	no	12.206	11.761	EPSD	COSMIC	10.658	Down-regulation
Atypical_PIKK_ATR_ATR_ST	Q12888	TP53BP1	Q13535	ATR	S1462	R1458H	1458	Missense	distal	-4	no	12.642	12.644	EPSD	COSMIC	10.658	Up-regulation
Atypical_PIKK_ATR_ATR_ST	Q12888	TP53BP1	Q13535	ATR	S1474	S1480F	1480	Missense	distal	6	no	11.193	11.035	EPSD	COSMIC	10.658	Down-regulation
Atypical_PIKK_ATR_ATR_ST	Q12888	TP53BP1	Q13535	ATR	S1660	P1657S	1657	Missense	distal	-3	no	13.393	13.116	EPSD	COSMIC	10.658	Down-regulation
Atypical_PIKK_ATR_ATR_ST	Q12888	TP53BP1	Q13535	ATR	S1660	A1659V	1659	Missense	proximal	-1	no	13.393	13.137	EPSD	COSMIC	10.658	Down-regulation
Atypical_PIKK_ATR_ATR_ST	Q12888	TP53BP1	Q13535	ATR	S1660	M1661T	1661	Missense	proximal	1	no	13.393	7.960	EPSD	COSMIC	10.658	Loss
Atypical_PIKK_ATR_ATR_ST	Q12888	TP53BP1	Q13535	ATR	S1673	P1679S	1679	Missense	distal	6	no	10.630	10.927	EPSD	COSMIC	10.658	Gain
Atypical_PIKK_ATR_ATR_ST	Q12888	TP53BP1	Q13535	ATR	S1678	E1676Q	1676	Missense	proximal	-2	no	10.995	11.030	EPSD	COSMIC	10.658	Up-regulation
Atypical_PIKK_ATR_ATR_ST	Q12888	TP53BP1	Q13535	ATR	S1678	P1679S	1679	Missense	proximal	1	no	10.995	9.886	EPSD	COSMIC	10.658	Loss
Atypical_PIKK_ATR_ATR_ST	Q12888	TP53BP1	Q13535	ATR	S1778	T1776A	1776	Missense	proximal	-2	no	13.247	13.720	EPSD	COSMIC	10.658	Up-regulation
Atypical_PIKK_ATR_ATR_ST	Q96RL1	UIMC1	Q13535	ATR	S101	A96T	96	Missense	distal	-5	no	13.164	13.080	EPSD	COSMIC	10.658	Down-regulation
Atypical_PIKK_ATR_ATR_ST	Q96RL1	UIMC1	Q13535	ATR	S140	P138S	138	Missense	proximal	-2	no	13.466	13.415	EPSD	COSMIC	10.658	Down-regulation
Atypical_PIKK_ATR_ATR_ST	Q96RL1	UIMC1	Q13535	ATR	S140	P138L	138	Missense	proximal	-2	no	13.466	14.117	EPSD	COSMIC;GDSC;CCLE	10.658	Up-regulation
Atypical_PIKK_ATR_ATR_ST	Q96RL1	UIMC1	Q13535	ATR	S197	D202V	202	Missense	distal	5	no	13.499	13.491	EPSD	COSMIC	10.658	Down-regulation
Atypical_PIKK_ATR_ATR_ST	Q96RL1	UIMC1	Q13535	ATR	S197	S198T	198	Missense	proximal	1	no	13.499	9.957	EPSD	COSMIC	10.658	Loss
Atypical_PIKK_ATR_ATR_ST	Q96RL1	UIMC1	Q13535	ATR	S197	S204L	204	Missense	distal	7	no	13.499	13.660	EPSD	COSMIC	10.658	Up-regulation
Atypical_PIKK_ATR_ATR_ST	Q96RL1	UIMC1	Q13535	ATR	S197	P193L	193	Missense	distal	-4	no	13.499	12.299	EPSD	COSMIC	10.658	Down-regulation
Atypical_PIKK_ATR_ATR_ST	Q96RL1	UIMC1	Q13535	ATR	S197	E191D	191	Missense	distal	-6	no	13.499	13.506	EPSD	COSMIC	10.658	Up-regulation
Atypical_PIKK_ATR_ATR_ST	Q96RL1	UIMC1	Q13535	ATR	S205	F209S	209	Missense	distal	4	no	16.798	16.779	PhosphoSitePlus	COSMIC	10.658	Down-regulation
Atypical_PIKK_ATR_ATR_ST	Q96RL1	UIMC1	Q13535	ATR	S205	D202V	202	Missense	distal	-3	no	16.798	16.446	PhosphoSitePlus	COSMIC	10.658	Down-regulation
Atypical_PIKK_ATR_ATR_ST	Q96RL1	UIMC1	Q13535	ATR	S205	V212A	212	Missense	distal	7	no	16.798	16.658	PhosphoSitePlus	COSMIC	10.658	Down-regulation
Atypical_PIKK_ATR_ATR_ST	Q96RL1	UIMC1	Q13535	ATR	S205	S198T	198	Missense	distal	-7	no	16.798	16.740	PhosphoSitePlus	COSMIC	10.658	Down-regulation
Atypical_PIKK_ATR_ATR_ST	Q96RL1	UIMC1	Q13535	ATR	S205	S204L	204	Missense	proximal	-1	no	16.798	17.034	PhosphoSitePlus	COSMIC	10.658	Up-regulation
Atypical_PIKK_ATR_ATR_ST	Q96RL1	UIMC1	Q13535	ATR	S379	L384S	384	Missense	distal	5	no	10.760	10.753	EPSD	COSMIC	10.658	Down-regulation
Atypical_PIKK_ATR_ATR_ST	Q96RL1	UIMC1	Q13535	ATR	S397	H398Q	398	Missense	proximal	1	no	-1.084	16.434	EPSD	COSMIC	10.658	Gain
Atypical_PIKK_ATR_ATR_ST	Q96RL1	UIMC1	Q13535	ATR	S402	T409P	409	Missense	distal	7	no	13.743	13.734	EPSD	COSMIC	10.658	Down-regulation
Atypical_PIKK_ATR_ATR_ST	Q96RL1	UIMC1	Q13535	ATR	S402	H398Q	398	Missense	distal	-4	no	13.743	13.923	EPSD	COSMIC	10.658	Up-regulation
Atypical_PIKK_ATR_ATR_ST	Q96RL1	UIMC1	Q13535	ATR	T448	T455I	455	Missense	distal	7	no	12.626	12.774	EPSD	COSMIC	10.658	Up-regulation
Atypical_PIKK_ATR_ATR_ST	Q96RL1	UIMC1	Q13535	ATR	T448	E454D	454	Missense	distal	6	no	12.626	12.351	EPSD	COSMIC	10.658	Down-regulation
Atypical_PIKK_ATR_ATR_ST	Q96RL1	UIMC1	Q13535	ATR	T448	C445F	445	Missense	distal	-3	no	12.626	13.074	EPSD	COSMIC	10.658	Up-regulation
Atypical_PIKK_ATR_ATR_ST	Q96RL1	UIMC1	Q13535	ATR	S451	T455I	455	Missense	distal	4	no	10.503	11.135	EPSD	COSMIC	10.658	Gain
Atypical_PIKK_ATR_ATR_ST	Q96RL1	UIMC1	Q13535	ATR	S643	K642N	642	Missense	proximal	-1	no	10.768	11.353	EPSD	COSMIC	10.658	Up-regulation
Atypical_PIKK_ATR_ATR_ST	Q96RL1	UIMC1	Q13535	ATR	S644	K642N	642	Missense	proximal	-2	no	10.887	11.341	EPSD	COSMIC	10.658	Up-regulation
Atypical_PIKK_ATR_ATR_ST	Q96RL1	UIMC1	Q13535	ATR	S662	A659T	659	Missense	distal	-3	no	10.850	10.288	EPSD	COSMIC	10.658	Loss
Atypical_PIKK_ATR_ATR_ST	Q96RL1	UIMC1	Q13535	ATR	S662	S668F	668	Missense	distal	6	no	10.850	10.691	EPSD	COSMIC	10.658	Down-regulation
Atypical_PIKK_ATR_ATR_ST	Q96RL1	UIMC1	Q13535	ATR	S677	D673N	673	Missense	distal	-4	no	12.139	11.530	EPSD	COSMIC	10.658	Down-regulation
Atypical_PIKK_ATR_ATR_ST	Q96RL1	UIMC1	Q13535	ATR	S677	P678L	678	Missense	proximal	1	no	12.139	11.573	EPSD	COSMIC	10.658	Down-regulation
Atypical_PIKK_ATR_ATR_ST	Q96RL1	UIMC1	Q13535	ATR	S677	V679I	679	Missense	proximal	2	no	12.139	10.829	EPSD	COSMIC	10.658	Down-regulation
Atypical_PIKK_ATR_ATR_ST	P39880	CUX1	Q13535	ATR	S59	A54V	54	Missense	distal	-5	no	10.657	10.659	EPSD	COSMIC	10.658	Gain
Atypical_PIKK_ATR_ATR_ST	P39880	CUX1	Q13535	ATR	S322	S320L	320	Missense	proximal	-2	no	14.706	15.408	EPSD	COSMIC	10.658	Up-regulation
Atypical_PIKK_ATR_ATR_ST	P39880	CUX1	Q13535	ATR	S322	A321V	321	Missense	proximal	-1	no	14.706	14.450	EPSD	COSMIC	10.658	Down-regulation
Atypical_PIKK_ATR_ATR_ST	P39880	CUX1	Q13535	ATR	S322	R317W	317	Missense	distal	-5	no	14.706	14.736	EPSD	COSMIC	10.658	Up-regulation
Atypical_PIKK_ATR_ATR_ST	P39880	CUX1	Q13535	ATR	S322	K315N	315	Missense	distal	-7	no	14.706	14.559	EPSD	COSMIC	10.658	Down-regulation
Atypical_PIKK_ATR_ATR_ST	P39880	CUX1	Q13535	ATR	S322	S322R	322	Missense	central	0	yes	14.706	0.000	EPSD	COSMIC	10.658	Loss
Atypical_PIKK_ATR_ATR_ST	P39880	CUX1	Q13535	ATR	S369	A372V	372	Missense	distal	3	no	10.632	11.392	EPSD	COSMIC	10.658	Gain
Atypical_PIKK_ATR_ATR_ST	P39880	CUX1	Q13535	ATR	S369	S363L	363	Missense	distal	-6	no	10.632	10.741	EPSD	COSMIC	10.658	Gain
Atypical_PIKK_ATR_ATR_ST	P39880	CUX1	Q13535	ATR	S369	M364V	364	Missense	distal	-5	no	10.632	10.833	EPSD	COSMIC	10.658	Gain
Atypical_PIKK_ATR_ATR_ST	P39880	CUX1	Q13535	ATR	S369	A372T	372	Missense	distal	3	no	10.632	10.944	EPSD	COSMIC	10.658	Gain
Atypical_PIKK_ATR_ATR_ST	P39880	CUX1	Q13535	ATR	S369	E370D	370	Missense	proximal	1	no	10.632	11.138	EPSD	COSMIC	10.658	Gain
Atypical_PIKK_ATR_ATR_ST	P39880	CUX1	Q13535	ATR	T374	A367T	367	Missense	distal	-7	no	15.839	15.816	EPSD	COSMIC	10.658	Down-regulation
Atypical_PIKK_ATR_ATR_ST	P39880	CUX1	Q13535	ATR	T374	A367V	367	Missense	distal	-7	no	15.839	15.818	EPSD	COSMIC	10.658	Down-regulation
Atypical_PIKK_ATR_ATR_ST	P39880	CUX1	Q13535	ATR	T374	A372V	372	Missense	proximal	-2	no	15.839	15.319	EPSD	COSMIC	10.658	Down-regulation
Atypical_PIKK_ATR_ATR_ST	P39880	CUX1	Q13535	ATR	T374	A372T	372	Missense	proximal	-2	no	15.839	15.366	EPSD	COSMIC	10.658	Down-regulation
Atypical_PIKK_ATR_ATR_ST	P39880	CUX1	Q13535	ATR	T374	A378S	378	Missense	distal	4	no	15.839	15.537	EPSD	COSMIC	10.658	Down-regulation
Atypical_PIKK_ATR_ATR_ST	P39880	CUX1	Q13535	ATR	T374	S369P	369	Missense	distal	-5	no	15.839	15.868	EPSD	COSMIC	10.658	Up-regulation
Atypical_PIKK_ATR_ATR_ST	P39880	CUX1	Q13535	ATR	T374	G373E	373	Missense	proximal	-1	no	15.839	15.887	EPSD	COSMIC	10.658	Up-regulation
Atypical_PIKK_ATR_ATR_ST	P39880	CUX1	Q13535	ATR	T374	E370K	370	Missense	distal	-4	no	15.839	15.428	EPSD	COSMIC	10.658	Down-regulation
Atypical_PIKK_ATR_ATR_ST	P39880	CUX1	Q13535	ATR	T374	E370D	370	Missense	distal	-4	no	15.839	15.657	EPSD	COSMIC	10.658	Down-regulation
Atypical_PIKK_ATR_ATR_ST	P39880	CUX1	Q13535	ATR	T374	A378V	378	Missense	distal	4	no	15.839	15.700	EPSD	COSMIC	10.658	Down-regulation
Atypical_PIKK_ATR_ATR_ST	P39880	CUX1	Q13535	ATR	T374	G373R	373	Missense	proximal	-1	no	15.839	15.872	EPSD	COSMIC	10.658	Up-regulation
Atypical_PIKK_ATR_ATR_ST	P39880	CUX1	Q13535	ATR	T374	G373V	373	Missense	proximal	-1	no	15.839	15.766	EPSD	COSMIC	10.658	Down-regulation
Atypical_PIKK_ATR_ATR_ST	P39880	CUX1	Q13535	ATR	S404	D405N	405	Missense	proximal	1	no	10.157	11.295	EPSD	COSMIC	10.658	Gain
Atypical_PIKK_ATR_ATR_ST	P39880	CUX1	Q13535	ATR	S404	S402L	402	Missense	proximal	-2	no	10.157	10.859	EPSD	COSMIC	10.658	Gain
Atypical_PIKK_ATR_ATR_ST	P39880	CUX1	Q13535	ATR	S432	G439V	439	Missense	distal	7	no	12.920	13.164	EPSD	COSMIC	10.658	Up-regulation
Atypical_PIKK_ATR_ATR_ST	P39880	CUX1	Q13535	ATR	S432	P430S	430	Missense	proximal	-2	no	12.920	12.868	EPSD	COSMIC	10.658	Down-regulation
Atypical_PIKK_ATR_ATR_ST	P39880	CUX1	Q13535	ATR	S432	Q433R	433	Missense	proximal	1	no	12.920	5.924	EPSD	COSMIC	10.658	Loss
Atypical_PIKK_ATR_ATR_ST	P39880	CUX1	Q13535	ATR	S667	A670V	670	Missense	distal	3	no	10.202	10.963	EPSD	COSMIC	10.658	Gain
Atypical_PIKK_ATR_ATR_ST	P39880	CUX1	Q13535	ATR	S673	I674M	674	Missense	proximal	1	no	10.218	13.622	EPSD	COSMIC	10.658	Gain
Atypical_PIKK_ATR_ATR_ST	P39880	CUX1	Q13535	ATR	S734	Q735H	735	Missense	proximal	1	no	14.868	-2.650	EPSD	COSMIC	10.658	Loss
Atypical_PIKK_ATR_ATR_ST	P39880	CUX1	Q13535	ATR	S734	D737N	737	Missense	distal	3	no	14.868	15.037	EPSD	COSMIC	10.658	Up-regulation
Atypical_PIKK_ATR_ATR_ST	P39880	CUX1	Q13535	ATR	S734	T739A	739	Missense	distal	5	no	14.868	14.871	EPSD	COSMIC	10.658	Up-regulation
Atypical_PIKK_ATR_ATR_ST	P39880	CUX1	Q13535	ATR	S734	A727V	727	Missense	distal	-7	no	14.868	14.847	EPSD	COSMIC	10.658	Down-regulation
Atypical_PIKK_ATR_ATR_ST	P39880	CUX1	Q13535	ATR	S734	S734R	734	Missense	central	0	yes	14.868	0.000	EPSD	COSMIC	10.658	Loss
Atypical_PIKK_ATR_ATR_ST	P39880	CUX1	Q13535	ATR	S749	T753A	753	Missense	distal	4	no	10.475	10.726	EPSD	COSMIC	10.658	Gain
Atypical_PIKK_ATR_ATR_ST	P39880	CUX1	Q13535	ATR	S756	T753A	753	Missense	distal	-3	no	10.192	10.754	EPSD	COSMIC	10.658	Gain
Atypical_PIKK_ATR_ATR_ST	P39880	CUX1	Q13535	ATR	S756	S755C	755	Missense	proximal	-1	no	10.192	10.743	EPSD	COSMIC	10.658	Gain
Atypical_PIKK_ATR_ATR_ST	P39880	CUX1	Q13535	ATR	S868	S875L	875	Missense	distal	7	no	11.489	11.651	EPSD	COSMIC;GDSC;CCLE	10.658	Up-regulation
Atypical_PIKK_ATR_ATR_ST	P39880	CUX1	Q13535	ATR	S868	E866K	866	Missense	proximal	-2	no	11.489	11.589	EPSD	COSMIC	10.658	Up-regulation
Atypical_PIKK_ATR_ATR_ST	P39880	CUX1	Q13535	ATR	S868	S875C	875	Missense	distal	7	no	11.489	11.851	EPSD	COSMIC	10.658	Up-regulation
Atypical_PIKK_ATR_ATR_ST	P39880	CUX1	Q13535	ATR	S868	P873L	873	Missense	distal	5	no	11.489	11.485	EPSD	COSMIC	10.658	Down-regulation
Atypical_PIKK_ATR_ATR_ST	P39880	CUX1	Q13535	ATR	S890	S887F	887	Missense	distal	-3	no	13.458	14.318	EPSD	COSMIC	10.658	Up-regulation
Atypical_PIKK_ATR_ATR_ST	P39880	CUX1	Q13535	ATR	S890	P888S	888	Missense	proximal	-2	no	13.458	13.407	EPSD	COSMIC	10.658	Down-regulation
Atypical_PIKK_ATR_ATR_ST	P39880	CUX1	Q13535	ATR	S890	P888A	888	Missense	proximal	-2	no	13.458	14.183	EPSD	COSMIC	10.658	Up-regulation
Atypical_PIKK_ATR_ATR_ST	P39880	CUX1	Q13535	ATR	S890	S892R	892	Missense	proximal	2	no	13.458	13.185	EPSD	COSMIC	10.658	Down-regulation
Atypical_PIKK_ATR_ATR_ST	P39880	CUX1	Q13535	ATR	S890	Q891K	891	Missense	proximal	1	no	13.458	2.492	EPSD	COSMIC	10.658	Loss
Atypical_PIKK_ATR_ATR_ST	P39880	CUX1	Q13535	ATR	S890	E894D	894	Missense	distal	4	no	13.458	13.648	EPSD	COSMIC	10.658	Up-regulation
Atypical_PIKK_ATR_ATR_ST	P39880	CUX1	Q13535	ATR	S890	P888L	888	Missense	proximal	-2	no	13.458	14.110	EPSD	COSMIC	10.658	Up-regulation
Atypical_PIKK_ATR_ATR_ST	P39880	CUX1	Q13535	ATR	S890	E886D	886	Missense	distal	-4	no	13.458	13.276	EPSD	COSMIC	10.658	Down-regulation
Atypical_PIKK_ATR_ATR_ST	P39880	CUX1	Q13535	ATR	S903	G899E	899	Missense	distal	-4	no	9.638	11.170	EPSD	COSMIC	10.658	Gain
Atypical_PIKK_ATR_ATR_ST	P39880	CUX1	Q13535	ATR	T923	K924N	924	Missense	proximal	1	no	7.515	14.205	EPSD	COSMIC	10.658	Gain
Atypical_PIKK_ATR_ATR_ST	P39880	CUX1	Q13535	ATR	T923	K924E	924	Missense	proximal	1	no	7.515	12.561	EPSD	COSMIC	10.658	Gain
Atypical_PIKK_ATR_ATR_ST	P39880	CUX1	Q13535	ATR	S974	S977N	977	Missense	distal	3	no	15.343	15.088	EPSD	COSMIC	10.658	Down-regulation
Atypical_PIKK_ATR_ATR_ST	P39880	CUX1	Q13535	ATR	S974	M981V	981	Missense	distal	7	no	15.343	15.559	EPSD	COSMIC	10.658	Up-regulation
Atypical_PIKK_ATR_ATR_ST	P39880	CUX1	Q13535	ATR	S974	K969E	969	Missense	distal	-5	no	15.343	15.262	EPSD	COSMIC	10.658	Down-regulation
Atypical_PIKK_ATR_ATR_ST	P39880	CUX1	Q13535	ATR	S974	K969N	969	Missense	distal	-5	no	15.343	15.488	EPSD	COSMIC	10.658	Up-regulation
Atypical_PIKK_ATR_ATR_ST	P39880	CUX1	Q13535	ATR	S974	V978I	978	Missense	distal	4	no	15.343	15.863	EPSD	COSMIC;GDSC	10.658	Up-regulation
Atypical_PIKK_ATR_ATR_ST	P39880	CUX1	Q13535	ATR	S974	G967R	967	Missense	distal	-7	no	15.343	15.344	EPSD	COSMIC;CCLE	10.658	Up-regulation
Atypical_PIKK_ATR_ATR_ST	P39880	CUX1	Q13535	ATR	S974	M981K	981	Missense	distal	7	no	15.343	15.460	EPSD	COSMIC	10.658	Up-regulation
Atypical_PIKK_ATR_ATR_ST	P39880	CUX1	Q13535	ATR	S974	G972C	972	Missense	proximal	-2	no	15.343	15.669	EPSD	COSMIC	10.658	Up-regulation
Atypical_PIKK_ATR_ATR_ST	P39880	CUX1	Q13535	ATR	S974	G972S	972	Missense	proximal	-2	no	15.343	15.030	EPSD	COSMIC	10.658	Down-regulation
Atypical_PIKK_ATR_ATR_ST	P39880	CUX1	Q13535	ATR	S1059	P1060L	1060	Missense	proximal	1	no	11.727	11.161	EPSD	COSMIC	10.658	Down-regulation
Atypical_PIKK_ATR_ATR_ST	P39880	CUX1	Q13535	ATR	S1059	P1055T	1055	Missense	distal	-4	no	11.727	11.315	EPSD	COSMIC	10.658	Down-regulation
Atypical_PIKK_ATR_ATR_ST	P39880	CUX1	Q13535	ATR	S1059	S1064R	1064	Missense	distal	5	no	11.727	11.738	EPSD	COSMIC	10.658	Up-regulation
Atypical_PIKK_ATR_ATR_ST	P39880	CUX1	Q13535	ATR	S1059	E1065G	1065	Missense	distal	6	no	11.727	11.399	EPSD	COSMIC	10.658	Down-regulation
Atypical_PIKK_ATR_ATR_ST	P39880	CUX1	Q13535	ATR	S1059	P1057H	1057	Missense	proximal	-2	no	11.727	11.639	EPSD	COSMIC	10.658	Down-regulation
Atypical_PIKK_ATR_ATR_ST	P39880	CUX1	Q13535	ATR	S1063	P1060L	1060	Missense	distal	-3	no	11.867	12.162	EPSD	COSMIC	10.658	Up-regulation
Atypical_PIKK_ATR_ATR_ST	P39880	CUX1	Q13535	ATR	S1063	K1068N	1068	Missense	distal	5	no	11.867	11.868	EPSD	COSMIC	10.658	Up-regulation
Atypical_PIKK_ATR_ATR_ST	P39880	CUX1	Q13535	ATR	S1063	S1064R	1064	Missense	proximal	1	no	11.867	10.849	EPSD	COSMIC	10.658	Down-regulation
Atypical_PIKK_ATR_ATR_ST	P39880	CUX1	Q13535	ATR	S1063	E1065G	1065	Missense	proximal	2	no	11.867	11.737	EPSD	COSMIC	10.658	Down-regulation
Atypical_PIKK_ATR_ATR_ST	P39880	CUX1	Q13535	ATR	S1063	P1057H	1057	Missense	distal	-6	no	11.867	11.910	EPSD	COSMIC	10.658	Up-regulation
Atypical_PIKK_ATR_ATR_ST	P39880	CUX1	Q13535	ATR	S1063	S1069F	1069	Missense	distal	6	no	11.867	11.709	EPSD	COSMIC	10.658	Down-regulation
Atypical_PIKK_ATR_ATR_ST	P39880	CUX1	Q13535	ATR	S1100	P1102H	1102	Missense	proximal	2	no	13.302	12.481	EPSD	COSMIC	10.658	Down-regulation
Atypical_PIKK_ATR_ATR_ST	P39880	CUX1	Q13535	ATR	S1100	P1105L	1105	Missense	distal	5	no	13.302	13.298	EPSD	COSMIC	10.658	Down-regulation
Atypical_PIKK_ATR_ATR_ST	P39880	CUX1	Q13535	ATR	S1100	P1095L	1095	Missense	distal	-5	no	13.302	13.455	EPSD	COSMIC	10.658	Up-regulation
Atypical_PIKK_ATR_ATR_ST	P39880	CUX1	Q13535	ATR	T1157	S1162F	1162	Missense	distal	5	no	11.672	11.684	EPSD	COSMIC;GDSC;CCLE	10.658	Up-regulation
Atypical_PIKK_ATR_ATR_ST	P39880	CUX1	Q13535	ATR	T1157	L1164I	1164	Missense	distal	7	no	11.672	11.830	EPSD	COSMIC	10.658	Up-regulation
Atypical_PIKK_ATR_ATR_ST	P39880	CUX1	Q13535	ATR	T1157	D1163Y	1163	Missense	distal	6	no	11.672	11.366	EPSD	COSMIC	10.658	Down-regulation
Atypical_PIKK_ATR_ATR_ST	P39880	CUX1	Q13535	ATR	T1157	G1159S	1159	Missense	proximal	2	no	11.672	10.734	EPSD	COSMIC	10.658	Down-regulation
Atypical_PIKK_ATR_ATR_ST	P39880	CUX1	Q13535	ATR	T1157	V1161I	1161	Missense	distal	4	no	11.672	12.192	EPSD	COSMIC	10.658	Up-regulation
Atypical_PIKK_ATR_ATR_ST	P39880	CUX1	Q13535	ATR	S1215	R1212W	1212	Missense	distal	-3	no	10.430	10.794	EPSD	COSMIC	10.658	Gain
Atypical_PIKK_ATR_ATR_ST	P39880	CUX1	Q13535	ATR	S1220	R1213Q	1213	Missense	distal	-7	no	12.448	12.480	EPSD	COSMIC	10.658	Up-regulation
Atypical_PIKK_ATR_ATR_ST	P39880	CUX1	Q13535	ATR	S1220	E1224K	1224	Missense	distal	4	no	12.448	12.559	EPSD	COSMIC	10.658	Up-regulation
Atypical_PIKK_ATR_ATR_ST	P39880	CUX1	Q13535	ATR	S1220	S1227F	1227	Missense	distal	7	no	12.448	12.510	EPSD	COSMIC	10.658	Up-regulation
Atypical_PIKK_ATR_ATR_ST	P39880	CUX1	Q13535	ATR	S1220	P1222S	1222	Missense	proximal	2	no	12.448	12.133	EPSD	COSMIC	10.658	Down-regulation
Atypical_PIKK_ATR_ATR_ST	P39880	CUX1	Q13535	ATR	S1220	P1226T	1226	Missense	distal	6	no	12.448	12.699	EPSD	COSMIC	10.658	Up-regulation
Atypical_PIKK_ATR_ATR_ST	P39880	CUX1	Q13535	ATR	S1233	V1228L	1228	Missense	distal	-5	no	14.612	14.696	EPSD	COSMIC	10.658	Up-regulation
Atypical_PIKK_ATR_ATR_ST	P39880	CUX1	Q13535	ATR	S1233	A1236G	1236	Missense	distal	3	no	14.612	14.779	EPSD	COSMIC	10.658	Up-regulation
Atypical_PIKK_ATR_ATR_ST	P39880	CUX1	Q13535	ATR	S1233	P1240H	1240	Missense	distal	7	no	14.612	14.701	EPSD	COSMIC	10.658	Up-regulation
Atypical_PIKK_ATR_ATR_ST	P39880	CUX1	Q13535	ATR	S1233	S1227F	1227	Missense	distal	-6	no	14.612	14.692	EPSD	COSMIC	10.658	Up-regulation
Atypical_PIKK_ATR_ATR_ST	P39880	CUX1	Q13535	ATR	S1233	A1236T	1236	Missense	distal	3	no	14.612	14.924	EPSD	COSMIC	10.658	Up-regulation
Atypical_PIKK_ATR_ATR_ST	P39880	CUX1	Q13535	ATR	S1233	E1231A	1231	Missense	proximal	-2	no	14.612	15.091	EPSD	COSMIC	10.658	Up-regulation
Atypical_PIKK_ATR_ATR_ST	P39880	CUX1	Q13535	ATR	S1233	P1226T	1226	Missense	distal	-7	no	14.612	14.526	EPSD	COSMIC	10.658	Down-regulation
Atypical_PIKK_ATR_ATR_ST	P39880	CUX1	Q13535	ATR	S1312	S1312G	1312	Missense	central	0	yes	12.391	0.000	EPSD	COSMIC	10.658	Loss
Atypical_PIKK_ATR_ATR_ST	P39880	CUX1	Q13535	ATR	S1312	A1310V	1310	Missense	proximal	-2	no	12.391	11.871	EPSD	COSMIC	10.658	Down-regulation
Atypical_PIKK_ATR_ATR_ST	P39880	CUX1	Q13535	ATR	S1312	G1311W	1311	Missense	proximal	-1	no	12.391	12.522	EPSD	COSMIC	10.658	Up-regulation
Atypical_PIKK_ATR_ATR_ST	P39880	CUX1	Q13535	ATR	S1312	I1305V	1305	Missense	distal	-7	no	12.391	12.452	EPSD	COSMIC	10.658	Up-regulation
Atypical_PIKK_ATR_ATR_ST	P39880	CUX1	Q13535	ATR	S1312	G1314D	1314	Missense	proximal	2	no	12.391	10.845	EPSD	COSMIC	10.658	Down-regulation
Atypical_PIKK_ATR_ATR_ST	P39880	CUX1	Q13535	ATR	S1312	Q1313L	1313	Missense	proximal	1	no	12.391	6.957	EPSD	COSMIC	10.658	Loss
Atypical_PIKK_ATR_ATR_ST	P39880	CUX1	Q13535	ATR	S1312	E1306K	1306	Missense	distal	-6	no	12.391	12.344	EPSD	COSMIC	10.658	Down-regulation
Atypical_PIKK_ATR_ATR_ST	P39880	CUX1	Q13535	ATR	S1321	R1325H	1325	Missense	distal	4	no	11.118	10.664	EPSD	COSMIC;CCLE	10.658	Down-regulation
Atypical_PIKK_ATR_ATR_ST	P39880	CUX1	Q13535	ATR	S1321	G1327C	1327	Missense	distal	6	no	11.118	11.177	EPSD	COSMIC	10.658	Up-regulation
Atypical_PIKK_ATR_ATR_ST	P39880	CUX1	Q13535	ATR	S1321	R1328Q	1328	Missense	distal	7	no	11.118	10.916	EPSD	COSMIC	10.658	Down-regulation
Atypical_PIKK_ATR_ATR_ST	P39880	CUX1	Q13535	ATR	S1321	S1326C	1326	Missense	distal	5	no	11.118	11.144	EPSD	COSMIC	10.658	Up-regulation
Atypical_PIKK_ATR_ATR_ST	P39880	CUX1	Q13535	ATR	S1321	R1325L	1325	Missense	distal	4	no	11.118	11.302	EPSD	COSMIC	10.658	Up-regulation
Atypical_PIKK_ATR_ATR_ST	P39880	CUX1	Q13535	ATR	S1321	R1325C	1325	Missense	distal	4	no	11.118	11.755	EPSD	COSMIC	10.658	Up-regulation
Atypical_PIKK_ATR_ATR_ST	P39880	CUX1	Q13535	ATR	S1321	G1314D	1314	Missense	distal	-7	no	11.118	11.149	EPSD	COSMIC	10.658	Up-regulation
Atypical_PIKK_ATR_ATR_ST	P39880	CUX1	Q13535	ATR	S1321	A1324T	1324	Missense	distal	3	no	11.118	11.430	EPSD	COSMIC	10.658	Up-regulation
Atypical_PIKK_ATR_ATR_ST	P39880	CUX1	Q13535	ATR	S1321	A1324V	1324	Missense	distal	3	no	11.118	11.878	EPSD	COSMIC	10.658	Up-regulation
Atypical_PIKK_ATR_ATR_ST	P39880	CUX1	Q13535	ATR	S1332	R1325H	1325	Missense	distal	-7	no	12.934	12.986	EPSD	COSMIC;CCLE	10.658	Up-regulation
Atypical_PIKK_ATR_ATR_ST	P39880	CUX1	Q13535	ATR	S1332	C1338F	1338	Missense	distal	6	no	12.934	12.959	EPSD	COSMIC	10.658	Up-regulation
Atypical_PIKK_ATR_ATR_ST	P39880	CUX1	Q13535	ATR	S1332	A1330V	1330	Missense	proximal	-2	no	12.934	12.414	EPSD	COSMIC	10.658	Down-regulation
Atypical_PIKK_ATR_ATR_ST	P39880	CUX1	Q13535	ATR	S1332	G1327C	1327	Missense	distal	-5	no	12.934	13.107	EPSD	COSMIC	10.658	Up-regulation
Atypical_PIKK_ATR_ATR_ST	P39880	CUX1	Q13535	ATR	S1332	R1328Q	1328	Missense	distal	-4	no	12.934	13.116	EPSD	COSMIC	10.658	Up-regulation
Atypical_PIKK_ATR_ATR_ST	P39880	CUX1	Q13535	ATR	S1332	S1326C	1326	Missense	distal	-6	no	12.934	13.003	EPSD	COSMIC	10.658	Up-regulation
Atypical_PIKK_ATR_ATR_ST	P39880	CUX1	Q13535	ATR	S1332	R1325L	1325	Missense	distal	-7	no	12.934	12.816	EPSD	COSMIC	10.658	Down-regulation
Atypical_PIKK_ATR_ATR_ST	P39880	CUX1	Q13535	ATR	S1332	S1337C	1337	Missense	distal	5	no	12.934	12.960	EPSD	COSMIC	10.658	Up-regulation
Atypical_PIKK_ATR_ATR_ST	P39880	CUX1	Q13535	ATR	S1332	E1334K	1334	Missense	proximal	2	no	12.934	11.985	EPSD	COSMIC	10.658	Down-regulation
Atypical_PIKK_ATR_ATR_ST	P39880	CUX1	Q13535	ATR	S1332	D1339V	1339	Missense	distal	7	no	12.934	12.987	EPSD	COSMIC	10.658	Up-regulation
Atypical_PIKK_ATR_ATR_ST	P39880	CUX1	Q13535	ATR	S1332	R1325C	1325	Missense	distal	-7	no	12.934	12.756	EPSD	COSMIC	10.658	Down-regulation
Atypical_PIKK_ATR_ATR_ST	P39880	CUX1	Q13535	ATR	S1332	A1330T	1330	Missense	proximal	-2	no	12.934	12.461	EPSD	COSMIC	10.658	Down-regulation
Atypical_PIKK_ATR_ATR_ST	P39880	CUX1	Q13535	ATR	T1352	E1353D	1353	Missense	proximal	1	no	10.321	10.827	EPSD	COSMIC	10.658	Gain
Atypical_PIKK_ATR_ATR_ST	P39880	CUX1	Q13535	ATR	S1357	Q1358L	1358	Missense	proximal	1	no	16.940	11.506	PhosphoSitePlus	COSMIC	10.658	Down-regulation
Atypical_PIKK_ATR_ATR_ST	P39880	CUX1	Q13535	ATR	S1357	A1350T	1350	Missense	distal	-7	no	16.940	16.917	PhosphoSitePlus	COSMIC	10.658	Down-regulation
Atypical_PIKK_ATR_ATR_ST	P39880	CUX1	Q13535	ATR	S1357	E1353D	1353	Missense	distal	-4	no	16.940	16.758	PhosphoSitePlus	COSMIC	10.658	Down-regulation
Atypical_PIKK_ATR_ATR_ST	P39880	CUX1	Q13535	ATR	S1357	A1361T	1361	Missense	distal	4	no	16.940	16.689	PhosphoSitePlus	COSMIC	10.658	Down-regulation
Atypical_PIKK_ATR_ATR_ST	P39880	CUX1	Q13535	ATR	T1373	R1368W	1368	Missense	distal	-5	no	11.054	11.084	EPSD	COSMIC	10.658	Up-regulation
Atypical_PIKK_ATR_ATR_ST	P39880	CUX1	Q13535	ATR	T1373	P1375L	1375	Missense	proximal	2	no	11.054	9.772	EPSD	COSMIC	10.658	Loss
Atypical_PIKK_ATR_ATR_ST	P39880	CUX1	Q13535	ATR	T1373	T1380I	1380	Missense	distal	7	no	11.054	11.202	EPSD	COSMIC	10.658	Up-regulation
Atypical_PIKK_ATR_ATR_ST	P39880	CUX1	Q13535	ATR	T1373	R1368Q	1368	Missense	distal	-5	no	11.054	10.961	EPSD	COSMIC	10.658	Down-regulation
Atypical_PIKK_ATR_ATR_ST	P39880	CUX1	Q13535	ATR	T1373	A1370V	1370	Missense	distal	-3	no	11.054	10.655	EPSD	COSMIC	10.658	Loss
Atypical_PIKK_ATR_ATR_ST	P39880	CUX1	Q13535	ATR	S1455	R1452M	1452	Missense	distal	-3	no	11.344	10.822	EPSD	COSMIC	10.658	Down-regulation
Atypical_PIKK_ATR_ATR_ST	P39880	CUX1	Q13535	ATR	S1455	G1461D	1461	Missense	distal	6	no	11.344	11.397	EPSD	COSMIC;CCLE	10.658	Up-regulation
Atypical_PIKK_ATR_ATR_ST	P39880	CUX1	Q13535	ATR	S1455	R1452Q	1452	Missense	distal	-3	no	11.344	11.160	EPSD	COSMIC	10.658	Down-regulation
Atypical_PIKK_ATR_ATR_ST	P39880	CUX1	Q13535	ATR	S1455	A1449T	1449	Missense	distal	-6	no	11.344	11.322	EPSD	COSMIC	10.658	Down-regulation
Atypical_PIKK_ATR_ATR_ST	P39880	CUX1	Q13535	ATR	S1496	R1497Q	1497	Missense	proximal	1	no	7.381	14.376	EPSD	COSMIC	10.658	Gain
Atypical_PIKK_ATR_ATR_ST	Q01094	E2F1	Q13535	ATR	S313	S318F	318	Missense	distal	5	no	14.237	14.250	EPSD	COSMIC	10.658	Up-regulation
Atypical_PIKK_ATR_ATR_ST	Q01094	E2F1	Q13535	ATR	S313	P312L	312	Missense	proximal	-1	no	14.237	14.258	EPSD	COSMIC	10.658	Up-regulation
Atypical_PIKK_ATR_ATR_ST	Q01094	E2F1	Q13535	ATR	S347	S341F	341	Missense	distal	-6	no	12.827	12.907	EPSD	COSMIC	10.658	Up-regulation
Atypical_PIKK_ATR_ATR_ST	Q01094	E2F1	Q13535	ATR	S347	P346S	346	Missense	proximal	-1	no	12.827	12.612	EPSD	COSMIC;GDSC	10.658	Down-regulation
Atypical_PIKK_ATR_ATR_ST	Q01094	E2F1	Q13535	ATR	S347	L350V	350	Missense	distal	3	no	12.827	13.594	EPSD	COSMIC	10.658	Up-regulation
Atypical_PIKK_ATR_ATR_ST	Q01094	E2F1	Q13535	ATR	S349	P346S	346	Missense	distal	-3	no	10.790	10.514	EPSD	COSMIC;GDSC	10.658	Loss
Atypical_PIKK_ATR_ATR_ST	Q01094	E2F1	Q13535	ATR	S349	L350V	350	Missense	proximal	1	no	10.790	-3.471	EPSD	COSMIC	10.658	Loss
Atypical_PIKK_ATR_ATR_ST	Q01094	E2F1	Q13535	ATR	S352	P346S	346	Missense	distal	-6	no	10.785	10.739	EPSD	COSMIC;GDSC	10.658	Down-regulation
Atypical_PIKK_ATR_ATR_ST	Q01094	E2F1	Q13535	ATR	S352	L350V	350	Missense	proximal	-2	no	10.785	10.338	EPSD	COSMIC	10.658	Loss
Atypical_PIKK_ATR_ATR_ST	Q01094	E2F1	Q13535	ATR	S364	R366Q	366	Missense	proximal	2	no	10.805	10.894	EPSD	COSMIC	10.658	Up-regulation
Atypical_PIKK_ATR_ATR_ST	P04637	TP53	Q13535	ATR	S6	E11Q	11	Missense	distal	5	no	10.901	10.908	EPSD	COSMIC;GDSC;CCLE	10.658	Up-regulation
Atypical_PIKK_ATR_ATR_ST	P04637	TP53	Q13535	ATR	S6	P13S	13	Missense	distal	7	no	10.901	10.738	EPSD	COSMIC	10.658	Down-regulation
Atypical_PIKK_ATR_ATR_ST	P04637	TP53	Q13535	ATR	S6	V10I	10	Missense	distal	4	no	10.901	11.421	EPSD	COSMIC	10.658	Up-regulation
Atypical_PIKK_ATR_ATR_ST	P04637	TP53	Q13535	ATR	S6	P8L	8	Missense	proximal	2	no	10.901	9.620	EPSD	COSMIC	10.658	Loss
Atypical_PIKK_ATR_ATR_ST	P04637	TP53	Q13535	ATR	S6	P8S	8	Missense	proximal	2	no	10.901	10.585	EPSD	COSMIC	10.658	Loss
Atypical_PIKK_ATR_ATR_ST	P04637	TP53	Q13535	ATR	S6	P13L	13	Missense	distal	7	no	10.901	10.899	EPSD	COSMIC	10.658	Down-regulation
Atypical_PIKK_ATR_ATR_ST	P04637	TP53	Q13535	ATR	S6	Q5H	5	Missense	proximal	-1	no	10.901	10.865	EPSD	COSMIC	10.658	Down-regulation
Atypical_PIKK_ATR_ATR_ST	P04637	TP53	Q13535	ATR	S6	V10G	10	Missense	distal	4	no	10.901	11.507	EPSD	COSMIC	10.658	Up-regulation
Atypical_PIKK_ATR_ATR_ST	P04637	TP53	Q13535	ATR	S6	E3G	3	Missense	distal	-3	no	10.901	10.742	EPSD	COSMIC	10.658	Down-regulation
Atypical_PIKK_ATR_ATR_ST	P04637	TP53	Q13535	ATR	S6	D7H	7	Missense	proximal	1	no	10.901	-1.203	EPSD	COSMIC	10.658	Loss
Atypical_PIKK_ATR_ATR_ST	P04637	TP53	Q13535	ATR	S6	S9G	9	Missense	distal	3	no	10.901	10.407	EPSD	COSMIC	10.658	Loss
Atypical_PIKK_ATR_ATR_ST	P04637	TP53	Q13535	ATR	S6	D7Y	7	Missense	proximal	1	no	10.901	10.001	EPSD	COSMIC	10.658	Loss
Atypical_PIKK_ATR_ATR_ST	P04637	TP53	Q13535	ATR	S15	E11Q	11	Missense	distal	-4	no	19.335	18.205	EPSD;PhosphoSitePlus	COSMIC;GDSC;CCLE	10.658	Down-regulation
Atypical_PIKK_ATR_ATR_ST	P04637	TP53	Q13535	ATR	S15	S20L	20	Missense	distal	5	no	19.335	19.342	EPSD;PhosphoSitePlus	COSMIC	10.658	Up-regulation
Atypical_PIKK_ATR_ATR_ST	P04637	TP53	Q13535	ATR	S15	Q16L	16	Missense	proximal	1	no	19.335	13.902	EPSD;PhosphoSitePlus	COSMIC;GDSC;CCLE	10.658	Down-regulation
Atypical_PIKK_ATR_ATR_ST	P04637	TP53	Q13535	ATR	S15	P13S	13	Missense	proximal	-2	no	19.335	19.284	EPSD;PhosphoSitePlus	COSMIC	10.658	Down-regulation
Atypical_PIKK_ATR_ATR_ST	P04637	TP53	Q13535	ATR	S15	E17K	17	Missense	proximal	2	no	19.335	18.386	EPSD;PhosphoSitePlus	COSMIC	10.658	Down-regulation
Atypical_PIKK_ATR_ATR_ST	P04637	TP53	Q13535	ATR	S15	V10I	10	Missense	distal	-5	no	19.335	19.440	EPSD;PhosphoSitePlus	COSMIC	10.658	Up-regulation
Atypical_PIKK_ATR_ATR_ST	P04637	TP53	Q13535	ATR	S15	P8L	8	Missense	distal	-7	no	19.335	19.143	EPSD;PhosphoSitePlus	COSMIC	10.658	Down-regulation
Atypical_PIKK_ATR_ATR_ST	P04637	TP53	Q13535	ATR	S15	P8S	8	Missense	distal	-7	no	19.335	19.308	EPSD;PhosphoSitePlus	COSMIC	10.658	Down-regulation
Atypical_PIKK_ATR_ATR_ST	P04637	TP53	Q13535	ATR	S15	P13L	13	Missense	proximal	-2	no	19.335	19.987	EPSD;PhosphoSitePlus	COSMIC	10.658	Up-regulation
Atypical_PIKK_ATR_ATR_ST	P04637	TP53	Q13535	ATR	S15	V10G	10	Missense	distal	-5	no	19.335	19.253	EPSD;PhosphoSitePlus	COSMIC	10.658	Down-regulation
Atypical_PIKK_ATR_ATR_ST	P04637	TP53	Q13535	ATR	S15	T18A	18	Missense	distal	3	no	19.335	19.024	EPSD;PhosphoSitePlus	COSMIC	10.658	Down-regulation
Atypical_PIKK_ATR_ATR_ST	P04637	TP53	Q13535	ATR	S15	F19S	19	Missense	distal	4	no	19.335	19.317	EPSD;PhosphoSitePlus	COSMIC	10.658	Down-regulation
Atypical_PIKK_ATR_ATR_ST	P04637	TP53	Q13535	ATR	S15	E17V	17	Missense	proximal	2	no	19.335	18.904	EPSD;PhosphoSitePlus	COSMIC	10.658	Down-regulation
Atypical_PIKK_ATR_ATR_ST	P04637	TP53	Q13535	ATR	S15	S9G	9	Missense	distal	-6	no	19.335	19.365	EPSD;PhosphoSitePlus	COSMIC	10.658	Up-regulation
Atypical_PIKK_ATR_ATR_ST	P04637	TP53	Q13535	ATR	S15	T18I	18	Missense	distal	3	no	19.335	19.693	EPSD;PhosphoSitePlus	COSMIC	10.658	Up-regulation
Atypical_PIKK_ATR_ATR_ST	P04637	TP53	Q13535	ATR	S15	T18K	18	Missense	distal	3	no	19.335	19.527	EPSD;PhosphoSitePlus	COSMIC	10.658	Up-regulation
Atypical_PIKK_ATR_ATR_ST	P04637	TP53	Q13535	ATR	S15	T18R	18	Missense	distal	3	no	19.335	19.249	EPSD;PhosphoSitePlus	COSMIC	10.658	Down-regulation
Atypical_PIKK_ATR_ATR_ST	P04637	TP53	Q13535	ATR	S15	S15I	15	Missense	central	0	yes	19.335	0.000	EPSD;PhosphoSitePlus	COSMIC	10.658	Loss
Atypical_PIKK_ATR_ATR_ST	P04637	TP53	Q13535	ATR	S37	M40I	40	Missense	distal	3	no	17.659	18.359	PhosphoSitePlus;EPSD	COSMIC	10.658	Up-regulation
Atypical_PIKK_ATR_ATR_ST	P04637	TP53	Q13535	ATR	S37	V31I	31	Missense	distal	-6	no	17.659	17.666	PhosphoSitePlus;EPSD	COSMIC;GDSC;CCLE	10.658	Up-regulation
Atypical_PIKK_ATR_ATR_ST	P04637	TP53	Q13535	ATR	S37	P36L	36	Missense	proximal	-1	no	17.659	17.680	PhosphoSitePlus;EPSD	COSMIC;GDSC;CCLE	10.658	Up-regulation
Atypical_PIKK_ATR_ATR_ST	P04637	TP53	Q13535	ATR	S37	S33T	33	Missense	distal	-4	no	17.659	17.573	PhosphoSitePlus;EPSD	COSMIC	10.658	Down-regulation
Atypical_PIKK_ATR_ATR_ST	P04637	TP53	Q13535	ATR	S37	D41N	41	Missense	distal	4	no	17.659	18.349	PhosphoSitePlus;EPSD	COSMIC	10.658	Up-regulation
Atypical_PIKK_ATR_ATR_ST	P04637	TP53	Q13535	ATR	S37	L35F	35	Missense	proximal	-2	no	17.659	17.555	PhosphoSitePlus;EPSD	COSMIC	10.658	Down-regulation
Atypical_PIKK_ATR_ATR_ST	P04637	TP53	Q13535	ATR	S37	Q38L	38	Missense	proximal	1	no	17.659	12.226	PhosphoSitePlus;EPSD	COSMIC	10.658	Down-regulation
Atypical_PIKK_ATR_ATR_ST	P04637	TP53	Q13535	ATR	S37	M44I	44	Missense	distal	7	no	17.659	17.985	PhosphoSitePlus;EPSD	COSMIC	10.658	Up-regulation
Atypical_PIKK_ATR_ATR_ST	P04637	TP53	Q13535	ATR	S37	P36S	36	Missense	proximal	-1	no	17.659	17.444	PhosphoSitePlus;EPSD	COSMIC;GDSC;CCLE	10.658	Down-regulation
Atypical_PIKK_ATR_ATR_ST	P04637	TP53	Q13535	ATR	S37	A39V	39	Missense	proximal	2	no	17.659	18.149	PhosphoSitePlus;EPSD	COSMIC	10.658	Up-regulation
Atypical_PIKK_ATR_ATR_ST	P04637	TP53	Q13535	ATR	S37	A39S	39	Missense	proximal	2	no	17.659	17.512	PhosphoSitePlus;EPSD	COSMIC	10.658	Down-regulation
Atypical_PIKK_ATR_ATR_ST	P04637	TP53	Q13535	ATR	S37	D42Y	42	Missense	distal	5	no	17.659	17.671	PhosphoSitePlus;EPSD	COSMIC	10.658	Up-regulation
Atypical_PIKK_ATR_ATR_ST	P04637	TP53	Q13535	ATR	S37	M44R	44	Missense	distal	7	no	17.659	17.888	PhosphoSitePlus;EPSD	COSMIC	10.658	Up-regulation
Atypical_PIKK_ATR_ATR_ST	P04637	TP53	Q13535	ATR	S37	M44V	44	Missense	distal	7	no	17.659	17.875	PhosphoSitePlus;EPSD	COSMIC	10.658	Up-regulation
Atypical_PIKK_ATR_ATR_ST	P04637	TP53	Q13535	ATR	S37	N30K	30	Missense	distal	-7	no	17.659	17.806	PhosphoSitePlus;EPSD	COSMIC	10.658	Up-regulation
Atypical_PIKK_ATR_ATR_ST	P04637	TP53	Q13535	ATR	S37	M44T	44	Missense	distal	7	no	17.659	17.836	PhosphoSitePlus;EPSD	COSMIC	10.658	Up-regulation
Atypical_PIKK_ATR_ATR_ST	P04637	TP53	Q13535	ATR	S37	A39T	39	Missense	proximal	2	no	17.659	17.121	PhosphoSitePlus;EPSD	COSMIC	10.658	Down-regulation
Atypical_PIKK_ATR_ATR_ST	P04637	TP53	Q13535	ATR	S37	L43F	43	Missense	distal	6	no	17.659	17.726	PhosphoSitePlus;EPSD	COSMIC	10.658	Up-regulation
Atypical_PIKK_ATR_ATR_ST	P04637	TP53	Q13535	ATR	S37	D41H	41	Missense	distal	4	no	17.659	17.310	PhosphoSitePlus;EPSD	COSMIC	10.658	Down-regulation
Atypical_PIKK_ATR_ATR_ST	P04637	TP53	Q13535	ATR	S37	P36R	36	Missense	proximal	-1	no	17.659	17.571	PhosphoSitePlus;EPSD	COSMIC	10.658	Down-regulation
Atypical_PIKK_ATR_ATR_ST	P04637	TP53	Q13535	ATR	S37	L35R	35	Missense	proximal	-2	no	17.659	17.366	PhosphoSitePlus;EPSD	COSMIC	10.658	Down-regulation
Atypical_PIKK_ATR_ATR_ST	P04637	TP53	Q13535	ATR	S37	L35H	35	Missense	proximal	-2	no	17.659	16.921	PhosphoSitePlus;EPSD	COSMIC	10.658	Down-regulation
Atypical_PIKK_ATR_ATR_ST	P04637	TP53	Q13535	ATR	S37	L35P	35	Missense	proximal	-2	no	17.659	17.008	PhosphoSitePlus;EPSD	COSMIC	10.658	Down-regulation
Atypical_PIKK_ATR_ATR_ST	P04637	TP53	Q13535	ATR	S37	L35I	35	Missense	proximal	-2	no	17.659	17.454	PhosphoSitePlus;EPSD	COSMIC	10.658	Down-regulation
Atypical_PIKK_ATR_ATR_ST	P04637	TP53	Q13535	ATR	S37	L35V	35	Missense	proximal	-2	no	17.659	17.213	PhosphoSitePlus;EPSD	COSMIC	10.658	Down-regulation
Atypical_PIKK_ATR_ATR_ST	P04637	TP53	Q13535	ATR	S37	D41E	41	Missense	distal	4	no	17.659	17.470	PhosphoSitePlus;EPSD	COSMIC	10.658	Down-regulation
Atypical_PIKK_ATR_ATR_ST	P04637	TP53	Q13535	ATR	S46	D48E	48	Missense	proximal	2	no	9.320	10.995	EPSD	COSMIC	10.658	Gain
Atypical_PIKK_ATR_ATR_ST	P04637	TP53	Q13535	ATR	S99	S99F	99	Missense	central	0	yes	13.266	0.000	EPSD	COSMIC	10.658	Loss
Atypical_PIKK_ATR_ATR_ST	P04637	TP53	Q13535	ATR	S99	S96F	96	Missense	distal	-3	no	13.266	14.125	EPSD	COSMIC	10.658	Up-regulation
Atypical_PIKK_ATR_ATR_ST	P04637	TP53	Q13535	ATR	S99	P98S	98	Missense	proximal	-1	no	13.266	13.051	EPSD	COSMIC;CCLE	10.658	Down-regulation
Atypical_PIKK_ATR_ATR_ST	P04637	TP53	Q13535	ATR	S99	T102I	102	Missense	distal	3	no	13.266	13.624	EPSD	COSMIC	10.658	Up-regulation
Atypical_PIKK_ATR_ATR_ST	P04637	TP53	Q13535	ATR	S99	S94P	94	Missense	distal	-5	no	13.266	13.295	EPSD	COSMIC	10.658	Up-regulation
Atypical_PIKK_ATR_ATR_ST	P04637	TP53	Q13535	ATR	S99	K101R	101	Missense	proximal	2	no	13.266	12.873	EPSD	COSMIC	10.658	Down-regulation
Atypical_PIKK_ATR_ATR_ST	P04637	TP53	Q13535	ATR	S99	S94T	94	Missense	distal	-5	no	13.266	13.278	EPSD	COSMIC	10.658	Up-regulation
Atypical_PIKK_ATR_ATR_ST	P04637	TP53	Q13535	ATR	S99	P98L	98	Missense	proximal	-1	no	13.266	13.287	EPSD	COSMIC;GDSC;CCLE	10.658	Up-regulation
Atypical_PIKK_ATR_ATR_ST	P04637	TP53	Q13535	ATR	S99	S95F	95	Missense	distal	-4	no	13.266	12.983	EPSD	COSMIC;CCLE	10.658	Down-regulation
Atypical_PIKK_ATR_ATR_ST	P04637	TP53	Q13535	ATR	S99	S96C	96	Missense	distal	-3	no	13.266	13.677	EPSD	COSMIC	10.658	Up-regulation
Atypical_PIKK_ATR_ATR_ST	P04637	TP53	Q13535	ATR	S99	S106I	106	Missense	distal	7	no	13.266	13.586	EPSD	COSMIC	10.658	Up-regulation
Atypical_PIKK_ATR_ATR_ST	P04637	TP53	Q13535	ATR	S99	P98F	98	Missense	proximal	-1	no	13.266	13.053	EPSD	COSMIC	10.658	Down-regulation
Atypical_PIKK_ATR_ATR_ST	P04637	TP53	Q13535	ATR	S99	T102P	102	Missense	distal	3	no	13.266	13.551	EPSD	COSMIC	10.658	Up-regulation
Atypical_PIKK_ATR_ATR_ST	P04637	TP53	Q13535	ATR	S99	S94L	94	Missense	distal	-5	no	13.266	13.448	EPSD	COSMIC	10.658	Up-regulation
Atypical_PIKK_ATR_ATR_ST	P04637	TP53	Q13535	ATR	S99	S96P	96	Missense	distal	-3	no	13.266	13.543	EPSD	COSMIC	10.658	Up-regulation
Atypical_PIKK_ATR_ATR_ST	P04637	TP53	Q13535	ATR	S99	P98T	98	Missense	proximal	-1	no	13.266	13.098	EPSD	COSMIC	10.658	Down-regulation
Atypical_PIKK_ATR_ATR_ST	P04637	TP53	Q13535	ATR	S99	S96Y	96	Missense	distal	-3	no	13.266	14.102	EPSD	COSMIC	10.658	Up-regulation
Atypical_PIKK_ATR_ATR_ST	P04637	TP53	Q13535	ATR	S99	S99P	99	Missense	central	0	yes	13.266	0.000	EPSD	COSMIC	10.658	Loss
Atypical_PIKK_ATR_ATR_ST	P04637	TP53	Q13535	ATR	S99	V97I	97	Missense	proximal	-2	no	13.266	13.507	EPSD	COSMIC	10.658	Up-regulation
Atypical_PIKK_ATR_ATR_ST	P04637	TP53	Q13535	ATR	S99	Q104H	104	Missense	distal	5	no	13.266	13.270	EPSD	COSMIC	10.658	Up-regulation
Atypical_PIKK_ATR_ATR_ST	P04637	TP53	Q13535	ATR	S99	L93M	93	Missense	distal	-6	no	13.266	13.221	EPSD	COSMIC	10.658	Down-regulation
Atypical_PIKK_ATR_ATR_ST	P04637	TP53	Q13535	ATR	S99	K101N	101	Missense	proximal	2	no	13.266	13.460	EPSD	COSMIC	10.658	Up-regulation
Atypical_PIKK_ATR_ATR_ST	P04637	TP53	Q13535	ATR	S99	V97A	97	Missense	proximal	-2	no	13.266	13.786	EPSD	COSMIC	10.658	Up-regulation
Atypical_PIKK_ATR_ATR_ST	P04637	TP53	Q13535	ATR	S99	P92A	92	Missense	distal	-7	no	13.266	13.204	EPSD	COSMIC	10.658	Down-regulation
Atypical_PIKK_ATR_ATR_ST	P04637	TP53	Q13535	ATR	S99	Q104L	104	Missense	distal	5	no	13.266	13.271	EPSD	COSMIC	10.658	Up-regulation
Atypical_PIKK_ATR_ATR_ST	P04637	TP53	Q13535	ATR	S99	P92L	92	Missense	distal	-7	no	13.266	13.073	EPSD	COSMIC	10.658	Down-regulation
Atypical_PIKK_ATR_ATR_ST	P04637	TP53	Q13535	ATR	S99	L93P	93	Missense	distal	-6	no	13.266	13.202	EPSD	COSMIC	10.658	Down-regulation
Atypical_PIKK_ATR_ATR_ST	P04637	TP53	Q13535	ATR	S99	L93F	93	Missense	distal	-6	no	13.266	13.236	EPSD	COSMIC	10.658	Down-regulation
Atypical_PIKK_ATR_ATR_ST	P04637	TP53	Q13535	ATR	S99	L93H	93	Missense	distal	-6	no	13.266	13.245	EPSD	COSMIC	10.658	Down-regulation
Atypical_PIKK_ATR_ATR_ST	P04637	TP53	Q13535	ATR	S99	S95Y	95	Missense	distal	-4	no	13.266	10.871	EPSD	COSMIC	10.658	Down-regulation
Atypical_PIKK_ATR_ATR_ST	P04637	TP53	Q13535	ATR	S106	G108C	108	Missense	proximal	2	no	11.409	8.787	EPSD	COSMIC	10.658	Loss
Atypical_PIKK_ATR_ATR_ST	P04637	TP53	Q13535	ATR	S106	S99F	99	Missense	distal	-7	no	11.409	11.301	EPSD	COSMIC	10.658	Down-regulation
Atypical_PIKK_ATR_ATR_ST	P04637	TP53	Q13535	ATR	S106	R110H	110	Missense	distal	4	no	11.409	10.955	EPSD	COSMIC	10.658	Down-regulation
Atypical_PIKK_ATR_ATR_ST	P04637	TP53	Q13535	ATR	S106	Y107Q	107	Missense	proximal	1	no	11.409	17.723	EPSD	COSMIC	10.658	Up-regulation
Atypical_PIKK_ATR_ATR_ST	P04637	TP53	Q13535	ATR	S106	T102I	102	Missense	distal	-4	no	11.409	10.154	EPSD	COSMIC	10.658	Loss
Atypical_PIKK_ATR_ATR_ST	P04637	TP53	Q13535	ATR	S106	K101R	101	Missense	distal	-5	no	11.409	11.594	EPSD	COSMIC	10.658	Up-regulation
Atypical_PIKK_ATR_ATR_ST	P04637	TP53	Q13535	ATR	S106	Y107C	107	Missense	proximal	1	no	11.409	5.044	EPSD	COSMIC	10.658	Loss
Atypical_PIKK_ATR_ATR_ST	P04637	TP53	Q13535	ATR	S106	S106I	106	Missense	central	0	yes	11.409	0.000	EPSD	COSMIC	10.658	Loss
Atypical_PIKK_ATR_ATR_ST	P04637	TP53	Q13535	ATR	S106	Y107H	107	Missense	proximal	1	no	11.409	0.205	EPSD	COSMIC	10.658	Loss
Atypical_PIKK_ATR_ATR_ST	P04637	TP53	Q13535	ATR	S106	T102P	102	Missense	distal	-4	no	11.409	11.821	EPSD	COSMIC	10.658	Up-regulation
Atypical_PIKK_ATR_ATR_ST	P04637	TP53	Q13535	ATR	S106	L111M	111	Missense	distal	5	no	11.409	11.411	EPSD	COSMIC	10.658	Up-regulation
Atypical_PIKK_ATR_ATR_ST	P04637	TP53	Q13535	ATR	S106	F109I	109	Missense	distal	3	no	11.409	12.449	EPSD	COSMIC	10.658	Up-regulation
Atypical_PIKK_ATR_ATR_ST	P04637	TP53	Q13535	ATR	S106	G108D	108	Missense	proximal	2	no	11.409	9.863	EPSD	COSMIC	10.658	Loss
Atypical_PIKK_ATR_ATR_ST	P04637	TP53	Q13535	ATR	S106	S99P	99	Missense	distal	-7	no	11.409	11.437	EPSD	COSMIC	10.658	Up-regulation
Atypical_PIKK_ATR_ATR_ST	P04637	TP53	Q13535	ATR	S106	Q104H	104	Missense	proximal	-2	no	11.409	11.042	EPSD	COSMIC	10.658	Down-regulation
Atypical_PIKK_ATR_ATR_ST	P04637	TP53	Q13535	ATR	S106	K101N	101	Missense	distal	-5	no	11.409	11.554	EPSD	COSMIC	10.658	Up-regulation
Atypical_PIKK_ATR_ATR_ST	P04637	TP53	Q13535	ATR	S106	Q104L	104	Missense	proximal	-2	no	11.409	11.781	EPSD	COSMIC	10.658	Up-regulation
Atypical_PIKK_ATR_ATR_ST	P04637	TP53	Q13535	ATR	S106	R110S	110	Missense	distal	4	no	11.409	11.357	EPSD	COSMIC	10.658	Down-regulation
Atypical_PIKK_ATR_ATR_ST	P04637	TP53	Q13535	ATR	S106	G112E	112	Missense	distal	6	no	11.409	11.737	EPSD	COSMIC	10.658	Up-regulation
Atypical_PIKK_ATR_ATR_ST	P04637	TP53	Q13535	ATR	S106	G112C	112	Missense	distal	6	no	11.409	11.468	EPSD	COSMIC	10.658	Up-regulation
Atypical_PIKK_ATR_ATR_ST	P04637	TP53	Q13535	ATR	S106	G112S	112	Missense	distal	6	no	11.409	11.651	EPSD	COSMIC	10.658	Up-regulation
Atypical_PIKK_ATR_ATR_ST	P04637	TP53	Q13535	ATR	S106	G112V	112	Missense	distal	6	no	11.409	11.538	EPSD	COSMIC	10.658	Up-regulation
Atypical_PIKK_ATR_ATR_ST	P04637	TP53	Q13535	ATR	S106	G112D	112	Missense	distal	6	no	11.409	11.462	EPSD	COSMIC	10.658	Up-regulation
Atypical_PIKK_ATR_ATR_ST	P04637	TP53	Q13535	ATR	S106	G112R	112	Missense	distal	6	no	11.409	11.255	EPSD	COSMIC	10.658	Down-regulation
Atypical_PIKK_ATR_ATR_ST	P04637	TP53	Q13535	ATR	S106	G112A	112	Missense	distal	6	no	11.409	11.326	EPSD	COSMIC	10.658	Down-regulation
Atypical_PIKK_ATR_ATR_ST	P04637	TP53	Q13535	ATR	S106	G112F	112	Missense	distal	6	no	11.409	11.493	EPSD	COSMIC	10.658	Up-regulation
Atypical_PIKK_ATR_ATR_ST	P04637	TP53	Q13535	ATR	S106	F113S	113	Missense	distal	7	no	11.409	11.347	EPSD	COSMIC;CCLE	10.658	Down-regulation
Atypical_PIKK_ATR_ATR_ST	P04637	TP53	Q13535	ATR	S106	F113P	113	Missense	distal	7	no	11.409	11.510	EPSD	COSMIC	10.658	Up-regulation
Atypical_PIKK_ATR_ATR_ST	P04637	TP53	Q13535	ATR	T211	R209Q	209	Missense	proximal	-2	no	10.866	10.787	EPSD	COSMIC	10.658	Down-regulation
Atypical_PIKK_ATR_ATR_ST	P04637	TP53	Q13535	ATR	T211	R209W	209	Missense	proximal	-2	no	10.866	10.972	EPSD	COSMIC	10.658	Up-regulation
Atypical_PIKK_ATR_ATR_ST	P04637	TP53	Q13535	ATR	T211	R209P	209	Missense	proximal	-2	no	10.866	10.508	EPSD	COSMIC	10.658	Loss
Atypical_PIKK_ATR_ATR_ST	P04637	TP53	Q13535	ATR	T211	R209L	209	Missense	proximal	-2	no	10.866	11.159	EPSD	COSMIC	10.658	Up-regulation
Atypical_PIKK_ATR_ATR_ST	P04637	TP53	Q13535	ATR	T211	R209G	209	Missense	proximal	-2	no	10.866	10.769	EPSD	COSMIC	10.658	Down-regulation
Atypical_PIKK_ATR_ATR_ST	P04637	TP53	Q13535	ATR	T211	R209C	209	Missense	proximal	-2	no	10.866	11.096	EPSD	COSMIC	10.658	Up-regulation
Atypical_PIKK_ATR_ATR_ST	P04637	TP53	Q13535	ATR	T211	E204K	204	Missense	distal	-7	no	10.866	10.848	EPSD	COSMIC	10.658	Down-regulation
Atypical_PIKK_ATR_ATR_ST	P04637	TP53	Q13535	ATR	T211	V216A	216	Missense	distal	5	no	10.866	10.875	EPSD	COSMIC	10.658	Up-regulation
Atypical_PIKK_ATR_ATR_ST	P04637	TP53	Q13535	ATR	T211	V217A	217	Missense	distal	6	no	10.866	10.653	EPSD	COSMIC	10.658	Loss
Atypical_PIKK_ATR_ATR_ST	P04637	TP53	Q13535	ATR	T211	E204G	204	Missense	distal	-7	no	10.866	10.788	EPSD	COSMIC	10.658	Down-regulation
Atypical_PIKK_ATR_ATR_ST	P04637	TP53	Q13535	ATR	T211	V218M	218	Missense	distal	7	no	10.866	10.650	EPSD	COSMIC	10.658	Loss
Atypical_PIKK_ATR_ATR_ST	P04637	TP53	Q13535	ATR	T211	D208E	208	Missense	distal	-3	no	10.866	10.273	EPSD	COSMIC	10.658	Loss
Atypical_PIKK_ATR_ATR_ST	P04637	TP53	Q13535	ATR	T211	F212L	212	Missense	proximal	1	no	10.866	12.116	EPSD	COSMIC	10.658	Up-regulation
Atypical_PIKK_ATR_ATR_ST	P04637	TP53	Q13535	ATR	T211	H214Q	214	Missense	distal	3	no	10.866	10.463	EPSD	COSMIC	10.658	Loss
Atypical_PIKK_ATR_ATR_ST	P04637	TP53	Q13535	ATR	T211	R213W	213	Missense	proximal	2	no	10.866	10.513	EPSD	COSMIC	10.658	Loss
Atypical_PIKK_ATR_ATR_ST	P04637	TP53	Q13535	ATR	T211	N210D	210	Missense	proximal	-1	no	10.866	10.575	EPSD	COSMIC	10.658	Loss
Atypical_PIKK_ATR_ATR_ST	P04637	TP53	Q13535	ATR	T211	V218A	218	Missense	distal	7	no	10.866	10.726	EPSD	COSMIC	10.658	Down-regulation
Atypical_PIKK_ATR_ATR_ST	P04637	TP53	Q13535	ATR	T211	S215C	215	Missense	distal	4	no	10.866	11.555	EPSD	COSMIC;GDSC;CCLE	10.658	Up-regulation
Atypical_PIKK_ATR_ATR_ST	P04637	TP53	Q13535	ATR	T211	V218L	218	Missense	distal	7	no	10.866	10.817	EPSD	COSMIC;GDSC;CCLE	10.658	Down-regulation
Atypical_PIKK_ATR_ATR_ST	P04637	TP53	Q13535	ATR	T211	E204V	204	Missense	distal	-7	no	10.866	10.780	EPSD	COSMIC	10.658	Down-regulation
Atypical_PIKK_ATR_ATR_ST	P04637	TP53	Q13535	ATR	T211	T211N	211	Missense	central	0	yes	10.866	0.000	EPSD	COSMIC	10.658	Loss
Atypical_PIKK_ATR_ATR_ST	P04637	TP53	Q13535	ATR	T211	N210S	210	Missense	proximal	-1	no	10.866	10.388	EPSD	COSMIC	10.658	Loss
Atypical_PIKK_ATR_ATR_ST	P04637	TP53	Q13535	ATR	T211	D207G	207	Missense	distal	-4	no	10.866	9.516	EPSD	COSMIC	10.658	Loss
Atypical_PIKK_ATR_ATR_ST	P04637	TP53	Q13535	ATR	T211	F212I	212	Missense	proximal	1	no	10.866	10.060	EPSD	COSMIC	10.658	Loss
Atypical_PIKK_ATR_ATR_ST	P04637	TP53	Q13535	ATR	T211	D207A	207	Missense	distal	-4	no	10.866	10.554	EPSD	COSMIC	10.658	Loss
Atypical_PIKK_ATR_ATR_ST	P04637	TP53	Q13535	ATR	T211	N210H	210	Missense	proximal	-1	no	10.866	10.409	EPSD	COSMIC	10.658	Loss
Atypical_PIKK_ATR_ATR_ST	P04637	TP53	Q13535	ATR	T211	V217E	217	Missense	distal	6	no	10.866	11.064	EPSD	COSMIC	10.658	Up-regulation
Atypical_PIKK_ATR_ATR_ST	P04637	TP53	Q13535	ATR	T211	R209T	209	Missense	proximal	-2	no	10.866	10.759	EPSD	COSMIC	10.658	Down-regulation
Atypical_PIKK_ATR_ATR_ST	P04637	TP53	Q13535	ATR	T211	D207Y	207	Missense	distal	-4	no	10.866	7.638	EPSD	COSMIC	10.658	Loss
Atypical_PIKK_ATR_ATR_ST	P04637	TP53	Q13535	ATR	T211	D208Y	208	Missense	distal	-3	no	10.866	10.909	EPSD	COSMIC	10.658	Up-regulation
Atypical_PIKK_ATR_ATR_ST	P04637	TP53	Q13535	ATR	T211	V217L	217	Missense	distal	6	no	10.866	10.754	EPSD	COSMIC	10.658	Down-regulation
Atypical_PIKK_ATR_ATR_ST	P04637	TP53	Q13535	ATR	T211	L206F	206	Missense	distal	-5	no	10.866	10.910	EPSD	COSMIC	10.658	Up-regulation
Atypical_PIKK_ATR_ATR_ST	P04637	TP53	Q13535	ATR	T211	E204A	204	Missense	distal	-7	no	10.866	10.801	EPSD	COSMIC	10.658	Down-regulation
Atypical_PIKK_ATR_ATR_ST	P04637	TP53	Q13535	ATR	T211	D208H	208	Missense	distal	-3	no	10.866	10.241	EPSD	COSMIC	10.658	Loss
Atypical_PIKK_ATR_ATR_ST	P04637	TP53	Q13535	ATR	T211	V217M	217	Missense	distal	6	no	10.866	10.639	EPSD	COSMIC	10.658	Loss
Atypical_PIKK_ATR_ATR_ST	P04637	TP53	Q13535	ATR	T211	D207E	207	Missense	distal	-4	no	10.866	11.048	EPSD	COSMIC	10.658	Up-regulation
Atypical_PIKK_ATR_ATR_ST	P04637	TP53	Q13535	ATR	T211	N210T	210	Missense	proximal	-1	no	10.866	10.435	EPSD	COSMIC	10.658	Loss
Atypical_PIKK_ATR_ATR_ST	P04637	TP53	Q13535	ATR	T211	N210K	210	Missense	proximal	-1	no	10.866	10.281	EPSD	COSMIC	10.658	Loss
Atypical_PIKK_ATR_ATR_ST	P04637	TP53	Q13535	ATR	T211	F212S	212	Missense	proximal	1	no	10.866	11.573	EPSD	COSMIC	10.658	Up-regulation
Atypical_PIKK_ATR_ATR_ST	P04637	TP53	Q13535	ATR	T211	H214P	214	Missense	distal	3	no	10.866	10.830	EPSD	COSMIC	10.658	Down-regulation
Atypical_PIKK_ATR_ATR_ST	P04637	TP53	Q13535	ATR	T211	D208I	208	Missense	distal	-3	no	10.866	10.097	EPSD	COSMIC	10.658	Loss
Atypical_PIKK_ATR_ATR_ST	P04637	TP53	Q13535	ATR	T211	F212Y	212	Missense	proximal	1	no	10.866	11.236	EPSD	COSMIC	10.658	Up-regulation
Atypical_PIKK_ATR_ATR_ST	P04637	TP53	Q13535	ATR	T211	H214A	214	Missense	distal	3	no	10.866	10.233	EPSD	COSMIC	10.658	Loss
Atypical_PIKK_ATR_ATR_ST	P04637	TP53	Q13535	ATR	T312	S313N	313	Missense	proximal	1	no	9.393	11.094	EPSD	COSMIC	10.658	Gain
Atypical_PIKK_ATR_ATR_ST	Q00987	MDM2	Q13535	ATR	S17	E23K	23	Missense	distal	6	no	14.492	14.293	EPSD	COSMIC	10.658	Down-regulation
Atypical_PIKK_ATR_ATR_ST	Q00987	MDM2	Q13535	ATR	S17	T10I	10	Missense	distal	-7	no	14.492	14.433	EPSD	COSMIC	10.658	Down-regulation
Atypical_PIKK_ATR_ATR_ST	Q00987	MDM2	Q13535	ATR	S17	D11N	11	Missense	distal	-6	no	14.492	14.495	EPSD	COSMIC	10.658	Up-regulation
Atypical_PIKK_ATR_ATR_ST	Q00987	MDM2	Q13535	ATR	S17	T16I	16	Missense	proximal	-1	no	14.492	14.718	EPSD	COSMIC	10.658	Up-regulation
Atypical_PIKK_ATR_ATR_ST	Q00987	MDM2	Q13535	ATR	S166	E167Q	167	Missense	proximal	1	no	9.643	15.564	EPSD	COSMIC	10.658	Gain
Atypical_PIKK_ATR_ATR_ST	Q00987	MDM2	Q13535	ATR	S176	G177D	177	Missense	proximal	1	no	7.425	10.955	EPSD	COSMIC	10.658	Gain
Atypical_PIKK_ATR_ATR_ST	Q00987	MDM2	Q13535	ATR	S229	E230Q	230	Missense	proximal	1	no	9.289	15.209	EPSD	COSMIC	10.658	Gain
Atypical_PIKK_ATR_ATR_ST	Q00987	MDM2	Q13535	ATR	S260	L261R	261	Missense	proximal	1	no	11.590	10.028	EPSD	COSMIC	10.658	Loss
Atypical_PIKK_ATR_ATR_ST	Q00987	MDM2	Q13535	ATR	S260	E257K	257	Missense	distal	-3	no	11.590	11.315	EPSD	COSMIC	10.658	Down-regulation
Atypical_PIKK_ATR_ATR_ST	Q00987	MDM2	Q13535	ATR	S260	S253Y	253	Missense	distal	-7	no	11.590	11.417	EPSD	COSMIC	10.658	Down-regulation
Atypical_PIKK_ATR_ATR_ST	Q00987	MDM2	Q13535	ATR	S260	S262N	262	Missense	proximal	2	no	11.590	11.903	EPSD	COSMIC	10.658	Up-regulation
Atypical_PIKK_ATR_ATR_ST	Q00987	MDM2	Q13535	ATR	S260	D255N	255	Missense	distal	-5	no	11.590	11.564	EPSD	COSMIC	10.658	Down-regulation
Atypical_PIKK_ATR_ATR_ST	Q00987	MDM2	Q13535	ATR	S260	L254V	254	Missense	distal	-6	no	11.590	11.558	EPSD	COSMIC	10.658	Down-regulation
Atypical_PIKK_ATR_ATR_ST	Q00987	MDM2	Q13535	ATR	S260	G265E	265	Missense	distal	5	no	11.590	11.579	EPSD	COSMIC	10.658	Down-regulation
Atypical_PIKK_ATR_ATR_ST	Q00987	MDM2	Q13535	ATR	S260	E263K	263	Missense	distal	3	no	11.590	11.747	EPSD	COSMIC	10.658	Up-regulation
Atypical_PIKK_ATR_ATR_ST	Q00987	MDM2	Q13535	ATR	S342	E340D	340	Missense	proximal	-2	no	10.821	10.917	EPSD	COSMIC	10.658	Up-regulation
Atypical_PIKK_ATR_ATR_ST	Q00987	MDM2	Q13535	ATR	S342	D337N	337	Missense	distal	-5	no	10.821	10.795	EPSD	COSMIC	10.658	Down-regulation
Atypical_PIKK_ATR_ATR_ST	Q00987	MDM2	Q13535	ATR	T351	G356S	356	Missense	distal	5	no	13.370	13.365	EPSD	COSMIC	10.658	Down-regulation
Atypical_PIKK_ATR_ATR_ST	Q00987	MDM2	Q13535	ATR	T351	E355Q	355	Missense	distal	4	no	13.370	13.499	EPSD	COSMIC	10.658	Up-regulation
Atypical_PIKK_ATR_ATR_ST	Q00987	MDM2	Q13535	ATR	T351	E354K	354	Missense	distal	3	no	13.370	13.527	EPSD	COSMIC	10.658	Up-regulation
Atypical_PIKK_ATR_ATR_ST	Q00987	MDM2	Q13535	ATR	T351	E355K	355	Missense	distal	4	no	13.370	13.481	EPSD	COSMIC	10.658	Up-regulation
Atypical_PIKK_ATR_ATR_ST	Q00987	MDM2	Q13535	ATR	S386	Q384R	384	Missense	proximal	-2	no	15.080	15.159	EPSD	COSMIC	10.658	Up-regulation
Atypical_PIKK_ATR_ATR_ST	Q00987	MDM2	Q13535	ATR	S386	D393E	393	Missense	distal	7	no	15.080	14.885	EPSD	COSMIC	10.658	Down-regulation
Atypical_PIKK_ATR_ATR_ST	Q00987	MDM2	Q13535	ATR	S386	D393H	393	Missense	distal	7	no	15.080	15.176	EPSD	COSMIC	10.658	Up-regulation
Atypical_PIKK_ATR_ATR_ST	Q00987	MDM2	Q13535	ATR	S386	A385V	385	Missense	proximal	-1	no	15.080	14.824	EPSD	COSMIC	10.658	Down-regulation
Atypical_PIKK_ATR_ATR_ST	Q00987	MDM2	Q13535	ATR	S386	D379G	379	Missense	distal	-7	no	15.080	15.049	EPSD	COSMIC	10.658	Down-regulation
Atypical_PIKK_ATR_ATR_ST	Q00987	MDM2	Q13535	ATR	S388	Q384R	384	Missense	distal	-4	no	15.320	15.138	EPSD	COSMIC	10.658	Down-regulation
Atypical_PIKK_ATR_ATR_ST	Q00987	MDM2	Q13535	ATR	S388	D393E	393	Missense	distal	5	no	15.320	15.305	EPSD	COSMIC	10.658	Down-regulation
Atypical_PIKK_ATR_ATR_ST	Q00987	MDM2	Q13535	ATR	S388	D393H	393	Missense	distal	5	no	15.320	15.316	EPSD	COSMIC	10.658	Down-regulation
Atypical_PIKK_ATR_ATR_ST	Q00987	MDM2	Q13535	ATR	S388	A385V	385	Missense	distal	-3	no	15.320	14.921	EPSD	COSMIC	10.658	Down-regulation
Atypical_PIKK_ATR_ATR_ST	Q00987	MDM2	Q13535	ATR	S395	D393E	393	Missense	proximal	-2	no	15.232	15.135	EPSD	COSMIC	10.658	Down-regulation
Atypical_PIKK_ATR_ATR_ST	Q00987	MDM2	Q13535	ATR	S395	D393H	393	Missense	proximal	-2	no	15.232	14.803	EPSD	COSMIC	10.658	Down-regulation
Atypical_PIKK_ATR_ATR_ST	Q00987	MDM2	Q13535	ATR	S407	S407R	407	Missense	central	0	yes	15.477	0.000	PhosphoSitePlus	COSMIC	10.658	Loss
Atypical_PIKK_ATR_ATR_ST	Q00987	MDM2	Q13535	ATR	S407	E413K	413	Missense	distal	6	no	15.477	15.277	PhosphoSitePlus	COSMIC	10.658	Down-regulation
Atypical_PIKK_ATR_ATR_ST	Q00987	MDM2	Q13535	ATR	S407	S407G	407	Missense	central	0	yes	15.477	0.000	PhosphoSitePlus	COSMIC	10.658	Loss
Atypical_PIKK_ATR_ATR_ST	Q00987	MDM2	Q13535	ATR	S407	E413G	413	Missense	distal	6	no	15.477	15.150	PhosphoSitePlus	COSMIC	10.658	Down-regulation
Atypical_PIKK_ATR_ATR_ST	Q00987	MDM2	Q13535	ATR	S407	I403V	403	Missense	distal	-4	no	15.477	16.351	PhosphoSitePlus	COSMIC	10.658	Up-regulation
Atypical_PIKK_ATR_ATR_ST	Q00987	MDM2	Q13535	ATR	S407	Y405C	405	Missense	proximal	-2	no	15.477	15.277	PhosphoSitePlus	COSMIC	10.658	Down-regulation
Atypical_PIKK_ATR_ATR_ST	Q00987	MDM2	Q13535	ATR	S407	F414I	414	Missense	distal	7	no	15.477	15.735	PhosphoSitePlus	COSMIC	10.658	Up-regulation
Atypical_PIKK_ATR_ATR_ST	Q00987	MDM2	Q13535	ATR	S407	S407N	407	Missense	central	0	yes	15.477	0.000	PhosphoSitePlus	COSMIC	10.658	Loss
Atypical_PIKK_ATR_ATR_ST	Q00987	MDM2	Q13535	ATR	T419	E413K	413	Missense	distal	-6	no	13.417	13.370	EPSD	COSMIC	10.658	Down-regulation
Atypical_PIKK_ATR_ATR_ST	Q00987	MDM2	Q13535	ATR	T419	E413G	413	Missense	distal	-6	no	13.417	13.391	EPSD	COSMIC	10.658	Down-regulation
Atypical_PIKK_ATR_ATR_ST	Q00987	MDM2	Q13535	ATR	T419	E415Q	415	Missense	distal	-4	no	13.417	12.286	EPSD	COSMIC	10.658	Down-regulation
Atypical_PIKK_ATR_ATR_ST	Q00987	MDM2	Q13535	ATR	T419	T419I	419	Missense	central	0	yes	13.417	0.000	EPSD	COSMIC	10.658	Loss
Atypical_PIKK_ATR_ATR_ST	Q00987	MDM2	Q13535	ATR	T419	S425C	425	Missense	distal	6	no	13.417	13.233	EPSD	COSMIC	10.658	Down-regulation
Atypical_PIKK_ATR_ATR_ST	Q00987	MDM2	Q13535	ATR	T419	F414I	414	Missense	distal	-5	no	13.417	13.393	EPSD	COSMIC	10.658	Down-regulation
Atypical_PIKK_ATR_ATR_ST	Q00987	MDM2	Q13535	ATR	T419	V426A	426	Missense	distal	7	no	13.417	13.276	EPSD	COSMIC	10.658	Down-regulation
Atypical_PIKK_ATR_ATR_ST	Q96SD1	DCLRE1C	Q13535	ATR	T251	H254Y	254	Missense	distal	3	no	13.155	12.265	EPSD	COSMIC	10.658	Down-regulation
Atypical_PIKK_ATR_ATR_ST	Q96SD1	DCLRE1C	Q13535	ATR	T500	E498D	498	Missense	proximal	-2	no	12.716	12.812	EPSD	COSMIC;GDSC;CCLE	10.658	Up-regulation
Atypical_PIKK_ATR_ATR_ST	Q96SD1	DCLRE1C	Q13535	ATR	T500	N506D	506	Missense	distal	6	no	12.716	12.413	EPSD	COSMIC	10.658	Down-regulation
Atypical_PIKK_ATR_ATR_ST	Q96SD1	DCLRE1C	Q13535	ATR	T500	F507V	507	Missense	distal	7	no	12.716	12.864	EPSD	COSMIC;CCLE	10.658	Up-regulation
Atypical_PIKK_ATR_ATR_ST	Q96SD1	DCLRE1C	Q13535	ATR	T500	R495T	495	Missense	distal	-5	no	12.716	12.546	EPSD	COSMIC	10.658	Down-regulation
Atypical_PIKK_ATR_ATR_ST	Q96SD1	DCLRE1C	Q13535	ATR	S516	S510R	510	Missense	distal	-6	no	15.874	15.956	PhosphoSitePlus;EPSD	COSMIC	10.658	Up-regulation
Atypical_PIKK_ATR_ATR_ST	Q96SD1	DCLRE1C	Q13535	ATR	S516	S518L	518	Missense	proximal	2	no	15.874	14.909	PhosphoSitePlus;EPSD	COSMIC	10.658	Down-regulation
Atypical_PIKK_ATR_ATR_ST	Q96SD1	DCLRE1C	Q13535	ATR	S534	S534F	534	Missense	central	0	yes	14.932	0.000	EPSD	COSMIC	10.658	Loss
Atypical_PIKK_ATR_ATR_ST	Q96SD1	DCLRE1C	Q13535	ATR	S538	E545D	545	Missense	distal	7	no	11.890	12.085	EPSD	COSMIC	10.658	Up-regulation
Atypical_PIKK_ATR_ATR_ST	Q96SD1	DCLRE1C	Q13535	ATR	S538	S534F	534	Missense	distal	-4	no	11.890	11.606	EPSD	COSMIC	10.658	Down-regulation
Atypical_PIKK_ATR_ATR_ST	Q96SD1	DCLRE1C	Q13535	ATR	S548	E545D	545	Missense	distal	-3	no	14.606	15.199	EPSD	COSMIC	10.658	Up-regulation
Atypical_PIKK_ATR_ATR_ST	Q96SD1	DCLRE1C	Q13535	ATR	S553	D556H	556	Missense	distal	3	no	14.312	14.709	EPSD	COSMIC	10.658	Up-regulation
Atypical_PIKK_ATR_ATR_ST	Q96SD1	DCLRE1C	Q13535	ATR	S562	D569N	569	Missense	distal	7	no	15.032	15.256	EPSD	COSMIC	10.658	Up-regulation
Atypical_PIKK_ATR_ATR_ST	Q96SD1	DCLRE1C	Q13535	ATR	S562	N566H	566	Missense	distal	4	no	15.032	13.993	EPSD	COSMIC	10.658	Down-regulation
Atypical_PIKK_ATR_ATR_ST	Q96SD1	DCLRE1C	Q13535	ATR	S562	D556H	556	Missense	distal	-6	no	15.032	15.057	EPSD	COSMIC	10.658	Up-regulation
Atypical_PIKK_ATR_ATR_ST	Q96SD1	DCLRE1C	Q13535	ATR	S562	Q563H	563	Missense	proximal	1	no	15.032	-2.486	EPSD	COSMIC	10.658	Loss
Atypical_PIKK_ATR_ATR_ST	Q96SD1	DCLRE1C	Q13535	ATR	S645	D650E	650	Missense	distal	5	no	16.135	16.120	EPSD;PhosphoSitePlus	COSMIC	10.658	Down-regulation
Atypical_PIKK_ATR_ATR_ST	Q96SD1	DCLRE1C	Q13535	ATR	S645	S647N	647	Missense	proximal	2	no	16.135	16.448	EPSD;PhosphoSitePlus	COSMIC	10.658	Up-regulation
Atypical_PIKK_ATR_ATR_ST	Q96SD1	DCLRE1C	Q13535	ATR	S645	L639F	639	Missense	distal	-6	no	16.135	16.105	EPSD;PhosphoSitePlus	COSMIC	10.658	Down-regulation
Atypical_PIKK_ATR_ATR_ST	Q96SD1	DCLRE1C	Q13535	ATR	S645	S645F	645	Missense	central	0	yes	16.135	0.000	EPSD;PhosphoSitePlus	COSMIC	10.658	Loss
Atypical_PIKK_ATR_ATR_ST	Q8WVB6	CHTF18	Q13535	ATR	S74	A69T	69	Missense	distal	-5	no	17.341	17.257	PhosphoSitePlus	COSMIC	10.658	Down-regulation
Atypical_PIKK_ATR_ATR_ST	Q8WVB6	CHTF18	Q13535	ATR	S126	T128M	128	Missense	proximal	2	no	10.410	11.208	EPSD	COSMIC	10.658	Gain
Atypical_PIKK_ATR_ATR_ST	Q8WVB6	CHTF18	Q13535	ATR	S135	E141D	141	Missense	distal	6	no	11.554	11.279	EPSD	COSMIC	10.658	Down-regulation
Atypical_PIKK_ATR_ATR_ST	Q8WVB6	CHTF18	Q13535	ATR	S135	P134L	134	Missense	proximal	-1	no	11.554	11.575	EPSD	COSMIC	10.658	Up-regulation
Atypical_PIKK_ATR_ATR_ST	Q8WVB6	CHTF18	Q13535	ATR	S135	T128M	128	Missense	distal	-7	no	11.554	11.600	EPSD	COSMIC	10.658	Up-regulation
Atypical_PIKK_ATR_ATR_ST	Q8WVB6	CHTF18	Q13535	ATR	S405	P406S	406	Missense	proximal	1	no	11.745	10.635	EPSD	COSMIC;GDSC;CCLE	10.658	Loss
Atypical_PIKK_ATR_ATR_ST	Q8WVB6	CHTF18	Q13535	ATR	S405	R404C	404	Missense	proximal	-1	no	11.745	12.169	EPSD	COSMIC;GDSC	10.658	Up-regulation
Atypical_PIKK_ATR_ATR_ST	Q8WVB6	CHTF18	Q13535	ATR	T778	S782I	782	Missense	distal	4	no	11.475	12.158	EPSD	COSMIC	10.658	Up-regulation
Atypical_PIKK_ATR_ATR_ST	P23025	XPA	Q13535	ATR	S196	A199V	199	Missense	distal	3	no	16.492	17.253	PhosphoSitePlus;EPSD	COSMIC	10.658	Up-regulation
Atypical_PIKK_ATR_ATR_ST	P23025	XPA	Q13535	ATR	S196	E202K	202	Missense	distal	6	no	16.492	16.292	PhosphoSitePlus;EPSD	COSMIC	10.658	Down-regulation
Atypical_PIKK_ATR_ATR_ST	P23025	XPA	Q13535	ATR	S196	Q197R	197	Missense	proximal	1	no	16.492	9.497	PhosphoSitePlus;EPSD	COSMIC	10.658	Loss
Atypical_PIKK_ATR_ATR_ST	P08047	SP1	Q13535	ATR	S56	S59Y	59	Missense	distal	3	no	15.878	14.961	EPSD	COSMIC	10.658	Down-regulation
Atypical_PIKK_ATR_ATR_ST	P08047	SP1	Q13535	ATR	S73	E72K	72	Missense	proximal	-1	no	12.796	12.547	EPSD	COSMIC	10.658	Down-regulation
Atypical_PIKK_ATR_ATR_ST	P08047	SP1	Q13535	ATR	S73	N79K	79	Missense	distal	6	no	12.796	12.568	EPSD	COSMIC	10.658	Down-regulation
Atypical_PIKK_ATR_ATR_ST	P08047	SP1	Q13535	ATR	S81	Q86R	86	Missense	distal	5	no	12.168	12.177	EPSD	COSMIC	10.658	Up-regulation
Atypical_PIKK_ATR_ATR_ST	P08047	SP1	Q13535	ATR	S81	N79K	79	Missense	proximal	-2	no	12.168	11.715	EPSD	COSMIC	10.658	Down-regulation
Atypical_PIKK_ATR_ATR_ST	P08047	SP1	Q13535	ATR	S81	P84L	84	Missense	distal	3	no	12.168	11.565	EPSD	COSMIC	10.658	Down-regulation
Atypical_PIKK_ATR_ATR_ST	P08047	SP1	Q13535	ATR	S85	Q86R	86	Missense	proximal	1	no	13.390	6.394	EPSD	COSMIC	10.658	Loss
Atypical_PIKK_ATR_ATR_ST	P08047	SP1	Q13535	ATR	S85	T90A	90	Missense	distal	5	no	13.390	13.393	EPSD	COSMIC	10.658	Up-regulation
Atypical_PIKK_ATR_ATR_ST	P08047	SP1	Q13535	ATR	S85	N79K	79	Missense	distal	-6	no	13.390	13.332	EPSD	COSMIC	10.658	Down-regulation
Atypical_PIKK_ATR_ATR_ST	P08047	SP1	Q13535	ATR	S85	P84L	84	Missense	proximal	-1	no	13.390	13.410	EPSD	COSMIC	10.658	Up-regulation
Atypical_PIKK_ATR_ATR_ST	P08047	SP1	Q13535	ATR	T98	A97V	97	Missense	proximal	-1	no	11.907	11.651	EPSD	COSMIC	10.658	Down-regulation
Atypical_PIKK_ATR_ATR_ST	P08047	SP1	Q13535	ATR	T98	A104V	104	Missense	distal	6	no	11.907	12.120	EPSD	COSMIC	10.658	Up-regulation
Atypical_PIKK_ATR_ATR_ST	P08047	SP1	Q13535	ATR	T98	T98A	98	Missense	central	0	yes	11.907	0.000	EPSD	COSMIC;GDSC;CCLE	10.658	Loss
Atypical_PIKK_ATR_ATR_ST	P08047	SP1	Q13535	ATR	S101	A97V	97	Missense	distal	-4	no	16.948	15.959	PhosphoSitePlus	COSMIC	10.658	Down-regulation
Atypical_PIKK_ATR_ATR_ST	P08047	SP1	Q13535	ATR	S101	A104V	104	Missense	distal	3	no	16.948	17.708	PhosphoSitePlus	COSMIC	10.658	Up-regulation
Atypical_PIKK_ATR_ATR_ST	P08047	SP1	Q13535	ATR	S101	T98A	98	Missense	distal	-3	no	16.948	17.509	PhosphoSitePlus	COSMIC;GDSC;CCLE	10.658	Up-regulation
Atypical_PIKK_ATR_ATR_ST	P08047	SP1	Q13535	ATR	S732	T739P	739	Missense	distal	7	no	11.680	11.672	EPSD	COSMIC	10.658	Down-regulation
Atypical_PIKK_ATR_ATR_ST	P08047	SP1	Q13535	ATR	S732	G729S	729	Missense	distal	-3	no	11.680	11.639	EPSD	COSMIC	10.658	Down-regulation
Atypical_PIKK_ATR_ATR_ST	P08047	SP1	Q13535	ATR	S732	S728N	728	Missense	distal	-4	no	11.680	11.903	EPSD	COSMIC	10.658	Up-regulation
Atypical_PIKK_ATR_ATR_ST	P08047	SP1	Q13535	ATR	S732	A730E	730	Missense	proximal	-2	no	11.680	11.200	EPSD	COSMIC	10.658	Down-regulation
Atypical_PIKK_ATR_ATR_ST	P08047	SP1	Q13535	ATR	S732	S732L	732	Missense	central	0	yes	11.680	0.000	EPSD	COSMIC	10.658	Loss
Atypical_PIKK_ATR_ATR_ST	P08047	SP1	Q13535	ATR	T739	T739P	739	Missense	central	0	yes	10.850	0.000	EPSD	COSMIC	10.658	Loss
Atypical_PIKK_ATR_ATR_ST	P08047	SP1	Q13535	ATR	T739	T746P	746	Missense	distal	7	no	10.850	10.841	EPSD	COSMIC	10.658	Down-regulation
Atypical_PIKK_ATR_ATR_ST	P08047	SP1	Q13535	ATR	T739	S732L	732	Missense	distal	-7	no	10.850	10.684	EPSD	COSMIC	10.658	Down-regulation
Atypical_PIKK_ATR_ATR_ST	P38398	BRCA1	Q13535	ATR	S114	D120A	120	Missense	distal	6	no	16.320	16.183	EPSD	COSMIC	10.658	Down-regulation
Atypical_PIKK_ATR_ATR_ST	P38398	BRCA1	Q13535	ATR	S114	P115L	115	Missense	proximal	1	no	16.320	15.754	EPSD	COSMIC	10.658	Down-regulation
Atypical_PIKK_ATR_ATR_ST	P38398	BRCA1	Q13535	ATR	S114	F107Y	107	Missense	distal	-7	no	16.320	16.254	EPSD	COSMIC	10.658	Down-regulation
Atypical_PIKK_ATR_ATR_ST	P38398	BRCA1	Q13535	ATR	S114	N113S	113	Missense	proximal	-1	no	16.320	15.843	EPSD	COSMIC	10.658	Down-regulation
Atypical_PIKK_ATR_ATR_ST	P38398	BRCA1	Q13535	ATR	S114	E111K	111	Missense	distal	-3	no	16.320	16.045	EPSD	COSMIC	10.658	Down-regulation
Atypical_PIKK_ATR_ATR_ST	P38398	BRCA1	Q13535	ATR	S114	A108V	108	Missense	distal	-6	no	16.320	16.289	EPSD	COSMIC	10.658	Down-regulation
Atypical_PIKK_ATR_ATR_ST	P38398	BRCA1	Q13535	ATR	S114	E116K	116	Missense	proximal	2	no	16.320	15.371	EPSD	COSMIC	10.658	Down-regulation
Atypical_PIKK_ATR_ATR_ST	P38398	BRCA1	Q13535	ATR	S114	P115R	115	Missense	proximal	1	no	16.320	14.192	EPSD	COSMIC	10.658	Down-regulation
Atypical_PIKK_ATR_ATR_ST	P38398	BRCA1	Q13535	ATR	S127	R133C	133	Missense	distal	6	no	10.588	10.801	EPSD	COSMIC	10.658	Gain
Atypical_PIKK_ATR_ATR_ST	P38398	BRCA1	Q13535	ATR	S127	I124T	124	Missense	distal	-3	no	10.588	10.842	EPSD	COSMIC	10.658	Gain
Atypical_PIKK_ATR_ATR_ST	P38398	BRCA1	Q13535	ATR	T231	T236I	236	Missense	distal	5	no	11.059	11.063	EPSD	COSMIC	10.658	Up-regulation
Atypical_PIKK_ATR_ATR_ST	P38398	BRCA1	Q13535	ATR	T231	T231N	231	Missense	central	0	yes	11.059	0.000	EPSD	COSMIC	10.658	Loss
Atypical_PIKK_ATR_ATR_ST	P38398	BRCA1	Q13535	ATR	S281	L283V	283	Missense	proximal	2	no	9.606	11.208	EPSD	COSMIC	10.658	Gain
Atypical_PIKK_ATR_ATR_ST	P38398	BRCA1	Q13535	ATR	S308	K309Q	309	Missense	proximal	1	no	2.846	13.812	EPSD	COSMIC	10.658	Gain
Atypical_PIKK_ATR_ATR_ST	P38398	BRCA1	Q13535	ATR	S316	W321L	321	Missense	distal	5	no	13.275	13.271	EPSD	COSMIC	10.658	Down-regulation
Atypical_PIKK_ATR_ATR_ST	P38398	BRCA1	Q13535	ATR	S316	P311A	311	Missense	distal	-5	no	13.275	13.341	EPSD	COSMIC	10.658	Up-regulation
Atypical_PIKK_ATR_ATR_ST	P38398	BRCA1	Q13535	ATR	S316	K309Q	309	Missense	distal	-7	no	13.275	13.247	EPSD	COSMIC	10.658	Down-regulation
Atypical_PIKK_ATR_ATR_ST	P38398	BRCA1	Q13535	ATR	S316	Q310H	310	Missense	distal	-6	no	13.275	13.289	EPSD	COSMIC	10.658	Up-regulation
Atypical_PIKK_ATR_ATR_ST	P38398	BRCA1	Q13535	ATR	S316	S316G	316	Missense	central	0	yes	13.275	0.000	EPSD	COSMIC	10.658	Loss
Atypical_PIKK_ATR_ATR_ST	P38398	BRCA1	Q13535	ATR	S316	A314S	314	Missense	proximal	-2	no	13.275	12.500	EPSD	COSMIC	10.658	Down-regulation
Atypical_PIKK_ATR_ATR_ST	P38398	BRCA1	Q13535	ATR	T374	Q380E	380	Missense	distal	6	no	10.642	10.856	EPSD	COSMIC	10.658	Gain
Atypical_PIKK_ATR_ATR_ST	P38398	BRCA1	Q13535	ATR	S389	S387N	387	Missense	proximal	-2	no	10.011	10.860	EPSD	COSMIC	10.658	Gain
Atypical_PIKK_ATR_ATR_ST	P38398	BRCA1	Q13535	ATR	S395	G401E	401	Missense	distal	6	no	10.385	10.713	EPSD	COSMIC;GDSC;CCLE	10.658	Gain
Atypical_PIKK_ATR_ATR_ST	P38398	BRCA1	Q13535	ATR	S395	H399R	399	Missense	distal	4	no	10.385	10.839	EPSD	COSMIC	10.658	Gain
Atypical_PIKK_ATR_ATR_ST	P38398	BRCA1	Q13535	ATR	S405	G401E	401	Missense	distal	-4	no	9.602	11.133	EPSD	COSMIC;GDSC;CCLE	10.658	Gain
Atypical_PIKK_ATR_ATR_ST	P38398	BRCA1	Q13535	ATR	S425	D430N	430	Missense	distal	5	no	13.755	13.750	EPSD	COSMIC	10.658	Down-regulation
Atypical_PIKK_ATR_ATR_ST	P38398	BRCA1	Q13535	ATR	S425	S426L	426	Missense	proximal	1	no	13.755	14.299	EPSD	COSMIC	10.658	Up-regulation
Atypical_PIKK_ATR_ATR_ST	P38398	BRCA1	Q13535	ATR	S425	L432V	432	Missense	distal	7	no	13.755	13.804	EPSD	COSMIC	10.658	Up-regulation
Atypical_PIKK_ATR_ATR_ST	P38398	BRCA1	Q13535	ATR	S425	V419E	419	Missense	distal	-6	no	13.755	13.734	EPSD	COSMIC	10.658	Down-regulation
Atypical_PIKK_ATR_ATR_ST	P38398	BRCA1	Q13535	ATR	T528	G535R	535	Missense	distal	7	no	11.844	12.101	EPSD	COSMIC	10.658	Up-regulation
Atypical_PIKK_ATR_ATR_ST	P38398	BRCA1	Q13535	ATR	T528	I532F	532	Missense	distal	4	no	11.844	11.180	EPSD	COSMIC	10.658	Down-regulation
Atypical_PIKK_ATR_ATR_ST	P38398	BRCA1	Q13535	ATR	S646	E648Q	648	Missense	proximal	2	no	10.895	9.641	EPSD	COSMIC	10.658	Loss
Atypical_PIKK_ATR_ATR_ST	P38398	BRCA1	Q13535	ATR	S646	E649D	649	Missense	distal	3	no	10.895	10.784	EPSD	COSMIC	10.658	Down-regulation
Atypical_PIKK_ATR_ATR_ST	P38398	BRCA1	Q13535	ATR	S646	E649Q	649	Missense	distal	3	no	10.895	10.778	EPSD	COSMIC	10.658	Down-regulation
Atypical_PIKK_ATR_ATR_ST	P38398	BRCA1	Q13535	ATR	S646	E648K	648	Missense	proximal	2	no	10.895	9.946	EPSD	COSMIC	10.658	Loss
Atypical_PIKK_ATR_ATR_ST	P38398	BRCA1	Q13535	ATR	S646	D642H	642	Missense	distal	-4	no	10.895	9.766	EPSD	COSMIC	10.658	Loss
Atypical_PIKK_ATR_ATR_ST	P38398	BRCA1	Q13535	ATR	S646	K651N	651	Missense	distal	5	no	10.895	10.896	EPSD	COSMIC	10.658	Up-regulation
Atypical_PIKK_ATR_ATR_ST	P38398	BRCA1	Q13535	ATR	S646	S647N	647	Missense	proximal	1	no	10.895	12.596	EPSD	COSMIC	10.658	Up-regulation
Atypical_PIKK_ATR_ATR_ST	P38398	BRCA1	Q13535	ATR	S647	E648Q	648	Missense	proximal	1	no	7.444	13.365	EPSD	COSMIC	10.658	Gain
Atypical_PIKK_ATR_ATR_ST	P38398	BRCA1	Q13535	ATR	T715	N714D	714	Missense	proximal	-1	no	11.580	11.290	EPSD	COSMIC	10.658	Down-regulation
Atypical_PIKK_ATR_ATR_ST	P38398	BRCA1	Q13535	ATR	T715	S708F	708	Missense	distal	-7	no	11.580	11.472	EPSD	COSMIC	10.658	Down-regulation
Atypical_PIKK_ATR_ATR_ST	P38398	BRCA1	Q13535	ATR	T715	T710I	710	Missense	distal	-5	no	11.580	11.771	EPSD	COSMIC	10.658	Up-regulation
Atypical_PIKK_ATR_ATR_ST	P38398	BRCA1	Q13535	ATR	T715	S708C	708	Missense	distal	-7	no	11.580	11.355	EPSD	COSMIC	10.658	Down-regulation
Atypical_PIKK_ATR_ATR_ST	P38398	BRCA1	Q13535	ATR	T715	S716F	716	Missense	proximal	1	no	11.580	10.873	EPSD	COSMIC	10.658	Down-regulation
Atypical_PIKK_ATR_ATR_ST	P38398	BRCA1	Q13535	ATR	S803	N810T	810	Missense	distal	7	no	12.969	12.759	EPSD	COSMIC;GDSC;CCLE	10.658	Down-regulation
Atypical_PIKK_ATR_ATR_ST	P38398	BRCA1	Q13535	ATR	S803	N810Y	810	Missense	distal	7	no	12.969	12.773	EPSD	COSMIC	10.658	Down-regulation
Atypical_PIKK_ATR_ATR_ST	P38398	BRCA1	Q13535	ATR	S803	E809G	809	Missense	distal	6	no	12.969	12.642	EPSD	COSMIC	10.658	Down-regulation
Atypical_PIKK_ATR_ATR_ST	P38398	BRCA1	Q13535	ATR	S803	P798S	798	Missense	distal	-5	no	12.969	12.940	EPSD	COSMIC	10.658	Down-regulation
Atypical_PIKK_ATR_ATR_ST	P38398	BRCA1	Q13535	ATR	S803	A807T	807	Missense	distal	4	no	12.969	12.718	EPSD	COSMIC	10.658	Down-regulation
Atypical_PIKK_ATR_ATR_ST	P38398	BRCA1	Q13535	ATR	S803	T796A	796	Missense	distal	-7	no	12.969	12.992	EPSD	COSMIC	10.658	Up-regulation
Atypical_PIKK_ATR_ATR_ST	P38398	BRCA1	Q13535	ATR	S956	R951M	951	Missense	distal	-5	no	12.178	11.893	EPSD	COSMIC	10.658	Down-regulation
Atypical_PIKK_ATR_ATR_ST	P38398	BRCA1	Q13535	ATR	S956	E962K	962	Missense	distal	6	no	12.178	11.978	EPSD	COSMIC;GDSC;CCLE	10.658	Down-regulation
Atypical_PIKK_ATR_ATR_ST	P38398	BRCA1	Q13535	ATR	S956	R951K	951	Missense	distal	-5	no	12.178	11.993	EPSD	COSMIC	10.658	Down-regulation
Atypical_PIKK_ATR_ATR_ST	P38398	BRCA1	Q13535	ATR	S956	C953Y	953	Missense	distal	-3	no	12.178	12.603	EPSD	COSMIC	10.658	Up-regulation
Atypical_PIKK_ATR_ATR_ST	P38398	BRCA1	Q13535	ATR	S1101	P1099S	1099	Missense	proximal	-2	no	11.797	11.746	EPSD	COSMIC	10.658	Down-regulation
Atypical_PIKK_ATR_ATR_ST	P38398	BRCA1	Q13535	ATR	S1101	L1098I	1098	Missense	distal	-3	no	11.797	11.250	EPSD	COSMIC	10.658	Down-regulation
Atypical_PIKK_ATR_ATR_ST	P38398	BRCA1	Q13535	ATR	S1101	K1104E	1104	Missense	distal	3	no	11.797	11.640	EPSD	COSMIC	10.658	Down-regulation
Atypical_PIKK_ATR_ATR_ST	P38398	BRCA1	Q13535	ATR	S1101	H1105N	1105	Missense	distal	4	no	11.797	12.836	EPSD	COSMIC	10.658	Up-regulation
Atypical_PIKK_ATR_ATR_ST	P38398	BRCA1	Q13535	ATR	S1143	S1140G	1140	Missense	distal	-3	no	16.363	16.404	EPSD;PhosphoSitePlus	COSMIC;GDSC	10.658	Up-regulation
Atypical_PIKK_ATR_ATR_ST	P38398	BRCA1	Q13535	ATR	S1143	G1138E	1138	Missense	distal	-5	no	16.363	16.263	EPSD;PhosphoSitePlus	COSMIC	10.658	Down-regulation
Atypical_PIKK_ATR_ATR_ST	P38398	BRCA1	Q13535	ATR	S1143	P1150S	1150	Missense	distal	7	no	16.363	16.200	EPSD;PhosphoSitePlus	COSMIC	10.658	Down-regulation
Atypical_PIKK_ATR_ATR_ST	P38398	BRCA1	Q13535	ATR	S1173	S1180I	1180	Missense	distal	7	no	10.919	11.239	EPSD	COSMIC	10.658	Up-regulation
Atypical_PIKK_ATR_ATR_ST	P38398	BRCA1	Q13535	ATR	S1173	E1167K	1167	Missense	distal	-6	no	10.919	10.872	EPSD	COSMIC	10.658	Down-regulation
Atypical_PIKK_ATR_ATR_ST	P38398	BRCA1	Q13535	ATR	S1239	Q1240E	1240	Missense	proximal	1	no	14.724	8.803	EPSD	COSMIC	10.658	Loss
Atypical_PIKK_ATR_ATR_ST	P38398	BRCA1	Q13535	ATR	S1239	S1245N	1245	Missense	distal	6	no	14.724	14.838	EPSD	COSMIC	10.658	Up-regulation
Atypical_PIKK_ATR_ATR_ST	P38398	BRCA1	Q13535	ATR	S1239	H1244Y	1244	Missense	distal	5	no	14.724	14.740	EPSD	COSMIC	10.658	Up-regulation
Atypical_PIKK_ATR_ATR_ST	P38398	BRCA1	Q13535	ATR	S1239	Q1240L	1240	Missense	proximal	1	no	14.724	9.291	EPSD	COSMIC	10.658	Loss
Atypical_PIKK_ATR_ATR_ST	P38398	BRCA1	Q13535	ATR	S1239	S1241F	1241	Missense	proximal	2	no	14.724	12.036	EPSD	COSMIC	10.658	Down-regulation
Atypical_PIKK_ATR_ATR_ST	P38398	BRCA1	Q13535	ATR	S1239	P1238H	1238	Missense	proximal	-1	no	14.724	14.530	EPSD	COSMIC	10.658	Down-regulation
Atypical_PIKK_ATR_ATR_ST	P38398	BRCA1	Q13535	ATR	S1239	T1246A	1246	Missense	distal	7	no	14.724	14.623	EPSD	COSMIC	10.658	Down-regulation
Atypical_PIKK_ATR_ATR_ST	P38398	BRCA1	Q13535	ATR	S1239	I1237L	1237	Missense	proximal	-2	no	14.724	14.930	EPSD	COSMIC	10.658	Up-regulation
Atypical_PIKK_ATR_ATR_ST	P38398	BRCA1	Q13535	ATR	S1239	S1245Y	1245	Missense	distal	6	no	14.724	14.228	EPSD	COSMIC	10.658	Down-regulation
Atypical_PIKK_ATR_ATR_ST	P38398	BRCA1	Q13535	ATR	S1239	S1245A	1245	Missense	distal	6	no	14.724	14.398	EPSD	COSMIC	10.658	Down-regulation
Atypical_PIKK_ATR_ATR_ST	P38398	BRCA1	Q13535	ATR	S1239	S1245F	1245	Missense	distal	6	no	14.724	14.566	EPSD	COSMIC	10.658	Down-regulation
Atypical_PIKK_ATR_ATR_ST	P38398	BRCA1	Q13535	ATR	S1262	N1255K	1255	Missense	distal	-7	no	10.595	10.742	EPSD	COSMIC	10.658	Gain
Atypical_PIKK_ATR_ATR_ST	P38398	BRCA1	Q13535	ATR	S1262	E1257K	1257	Missense	distal	-5	no	10.595	10.676	EPSD	COSMIC	10.658	Gain
Atypical_PIKK_ATR_ATR_ST	P38398	BRCA1	Q13535	ATR	S1262	K1264N	1264	Missense	proximal	2	no	10.595	10.789	EPSD	COSMIC	10.658	Gain
Atypical_PIKK_ATR_ATR_ST	P38398	BRCA1	Q13535	ATR	S1266	L1260V	1260	Missense	distal	-6	no	13.724	13.691	EPSD	COSMIC	10.658	Down-regulation
Atypical_PIKK_ATR_ATR_ST	P38398	BRCA1	Q13535	ATR	S1266	L1263F	1263	Missense	distal	-3	no	13.724	14.011	EPSD	COSMIC	10.658	Up-regulation
Atypical_PIKK_ATR_ATR_ST	P38398	BRCA1	Q13535	ATR	S1266	K1264N	1264	Missense	proximal	-2	no	13.724	14.177	EPSD	COSMIC	10.658	Up-regulation
Atypical_PIKK_ATR_ATR_ST	P38398	BRCA1	Q13535	ATR	S1280	K1278Q	1278	Missense	proximal	-2	no	18.710	18.645	PhosphoSitePlus;EPSD	COSMIC	10.658	Down-regulation
Atypical_PIKK_ATR_ATR_ST	P38398	BRCA1	Q13535	ATR	S1280	S1286T	1286	Missense	distal	6	no	18.710	18.663	PhosphoSitePlus;EPSD	COSMIC	10.658	Down-regulation
Atypical_PIKK_ATR_ATR_ST	P38398	BRCA1	Q13535	ATR	S1280	I1275V	1275	Missense	distal	-5	no	18.710	18.605	PhosphoSitePlus;EPSD	COSMIC	10.658	Down-regulation
Atypical_PIKK_ATR_ATR_ST	P38398	BRCA1	Q13535	ATR	S1280	H1284Y	1284	Missense	distal	4	no	18.710	19.566	PhosphoSitePlus;EPSD	COSMIC	10.658	Up-regulation
Atypical_PIKK_ATR_ATR_ST	P38398	BRCA1	Q13535	ATR	T1312	P1315S	1315	Missense	distal	3	no	12.498	12.562	EPSD	COSMIC	10.658	Up-regulation
Atypical_PIKK_ATR_ATR_ST	P38398	BRCA1	Q13535	ATR	T1312	A1308S	1308	Missense	distal	-4	no	12.498	11.977	EPSD	COSMIC	10.658	Down-regulation
Atypical_PIKK_ATR_ATR_ST	P38398	BRCA1	Q13535	ATR	T1312	N1309L	1309	Missense	distal	-3	no	12.498	11.985	EPSD	COSMIC	10.658	Down-regulation
Atypical_PIKK_ATR_ATR_ST	P38398	BRCA1	Q13535	ATR	T1312	T1310S	1310	Missense	proximal	-2	no	12.498	12.196	EPSD	COSMIC	10.658	Down-regulation
Atypical_PIKK_ATR_ATR_ST	P38398	BRCA1	Q13535	ATR	S1330	G1332R	1332	Missense	proximal	2	no	14.052	12.840	EPSD	COSMIC	10.658	Down-regulation
Atypical_PIKK_ATR_ATR_ST	P38398	BRCA1	Q13535	ATR	S1387	S1387F	1387	Missense	central	0	yes	15.877	0.000	EPSD	COSMIC	10.658	Loss
Atypical_PIKK_ATR_ATR_ST	P38398	BRCA1	Q13535	ATR	S1387	G1384W	1384	Missense	distal	-3	no	15.877	16.737	EPSD	COSMIC	10.658	Up-regulation
Atypical_PIKK_ATR_ATR_ST	P38398	BRCA1	Q13535	ATR	S1387	T1393N	1393	Missense	distal	6	no	15.877	16.038	EPSD	COSMIC	10.658	Up-regulation
Atypical_PIKK_ATR_ATR_ST	P38398	BRCA1	Q13535	ATR	S1387	Q1388E	1388	Missense	proximal	1	no	15.877	9.957	EPSD	COSMIC	10.658	Loss
Atypical_PIKK_ATR_ATR_ST	P38398	BRCA1	Q13535	ATR	S1387	Q1388H	1388	Missense	proximal	1	no	15.877	-1.641	EPSD	COSMIC	10.658	Loss
Atypical_PIKK_ATR_ATR_ST	P38398	BRCA1	Q13535	ATR	S1387	T1394I	1394	Missense	distal	7	no	15.877	16.025	EPSD	COSMIC;CCLE	10.658	Up-regulation
Atypical_PIKK_ATR_ATR_ST	P38398	BRCA1	Q13535	ATR	S1387	L1392F	1392	Missense	distal	5	no	15.877	15.883	EPSD	COSMIC	10.658	Up-regulation
Atypical_PIKK_ATR_ATR_ST	P38398	BRCA1	Q13535	ATR	S1387	S1387N	1387	Missense	central	0	yes	15.877	0.000	EPSD	COSMIC	10.658	Loss
Atypical_PIKK_ATR_ATR_ST	P38398	BRCA1	Q13535	ATR	T1394	S1387F	1387	Missense	distal	-7	no	13.794	13.686	EPSD	COSMIC	10.658	Down-regulation
Atypical_PIKK_ATR_ATR_ST	P38398	BRCA1	Q13535	ATR	T1394	Q1396H	1396	Missense	proximal	2	no	13.794	13.473	EPSD	COSMIC	10.658	Down-regulation
Atypical_PIKK_ATR_ATR_ST	P38398	BRCA1	Q13535	ATR	T1394	T1393N	1393	Missense	proximal	-1	no	13.794	14.225	EPSD	COSMIC	10.658	Up-regulation
Atypical_PIKK_ATR_ATR_ST	P38398	BRCA1	Q13535	ATR	T1394	Q1388E	1388	Missense	distal	-6	no	13.794	13.775	EPSD	COSMIC	10.658	Down-regulation
Atypical_PIKK_ATR_ATR_ST	P38398	BRCA1	Q13535	ATR	T1394	Q1395E	1395	Missense	proximal	1	no	13.794	7.873	EPSD	COSMIC	10.658	Loss
Atypical_PIKK_ATR_ATR_ST	P38398	BRCA1	Q13535	ATR	T1394	Q1388H	1388	Missense	distal	-6	no	13.794	13.808	EPSD	COSMIC	10.658	Up-regulation
Atypical_PIKK_ATR_ATR_ST	P38398	BRCA1	Q13535	ATR	T1394	T1394I	1394	Missense	central	0	yes	13.794	0.000	EPSD	COSMIC;CCLE	10.658	Loss
Atypical_PIKK_ATR_ATR_ST	P38398	BRCA1	Q13535	ATR	T1394	L1392F	1392	Missense	proximal	-2	no	13.794	13.690	EPSD	COSMIC	10.658	Down-regulation
Atypical_PIKK_ATR_ATR_ST	P38398	BRCA1	Q13535	ATR	T1394	S1387N	1387	Missense	distal	-7	no	13.794	13.660	EPSD	COSMIC	10.658	Down-regulation
Atypical_PIKK_ATR_ATR_ST	P38398	BRCA1	Q13535	ATR	S1423	E1419G	1419	Missense	distal	-4	no	15.492	13.961	EPSD;PhosphoSitePlus	COSMIC	10.658	Down-regulation
Atypical_PIKK_ATR_ATR_ST	P38398	BRCA1	Q13535	ATR	S1423	S1423R	1423	Missense	central	0	yes	15.492	0.000	EPSD;PhosphoSitePlus	COSMIC	10.658	Loss
Atypical_PIKK_ATR_ATR_ST	P38398	BRCA1	Q13535	ATR	S1423	S1426C	1426	Missense	distal	3	no	15.492	15.190	EPSD;PhosphoSitePlus	COSMIC	10.658	Down-regulation
Atypical_PIKK_ATR_ATR_ST	P38398	BRCA1	Q13535	ATR	S1423	S1426F	1426	Missense	distal	3	no	15.492	14.461	EPSD;PhosphoSitePlus	COSMIC	10.658	Down-regulation
Atypical_PIKK_ATR_ATR_ST	P38398	BRCA1	Q13535	ATR	S1423	S1426Y	1426	Missense	distal	3	no	15.492	14.575	EPSD;PhosphoSitePlus	COSMIC	10.658	Down-regulation
Atypical_PIKK_ATR_ATR_ST	P38398	BRCA1	Q13535	ATR	S1457	S1450P	1450	Missense	distal	-7	no	19.606	19.634	EPSD;PhosphoSitePlus	COSMIC	10.658	Up-regulation
Atypical_PIKK_ATR_ATR_ST	P38398	BRCA1	Q13535	ATR	S1466	G1471R	1471	Missense	distal	5	no	13.336	13.341	EPSD	COSMIC	10.658	Up-regulation
Atypical_PIKK_ATR_ATR_ST	P38398	BRCA1	Q13535	ATR	S1466	S1466C	1466	Missense	central	0	yes	13.336	0.000	EPSD	COSMIC	10.658	Loss
Atypical_PIKK_ATR_ATR_ST	P38398	BRCA1	Q13535	ATR	S1466	S1473Y	1473	Missense	distal	7	no	13.336	13.521	EPSD	COSMIC	10.658	Up-regulation
Atypical_PIKK_ATR_ATR_ST	P38398	BRCA1	Q13535	ATR	S1466	S1473F	1473	Missense	distal	7	no	13.336	13.397	EPSD	COSMIC	10.658	Up-regulation
Atypical_PIKK_ATR_ATR_ST	P38398	BRCA1	Q13535	ATR	S1466	S1466I	1466	Missense	central	0	yes	13.336	0.000	EPSD	COSMIC	10.658	Loss
Atypical_PIKK_ATR_ATR_ST	P38398	BRCA1	Q13535	ATR	S1524	Q1525H	1525	Missense	proximal	1	no	16.882	-0.636	EPSD;PhosphoSitePlus	COSMIC	10.658	Loss
Atypical_PIKK_ATR_ATR_ST	P38398	BRCA1	Q13535	ATR	S1524	K1530R	1530	Missense	distal	6	no	16.882	16.600	EPSD;PhosphoSitePlus	COSMIC	10.658	Down-regulation
Atypical_PIKK_ATR_ATR_ST	P38398	BRCA1	Q13535	ATR	S1524	N1519S	1519	Missense	distal	-5	no	16.882	16.740	EPSD;PhosphoSitePlus	COSMIC	10.658	Down-regulation
Atypical_PIKK_ATR_ATR_ST	P38398	BRCA1	Q13535	ATR	S1524	E1527D	1527	Missense	distal	3	no	16.882	16.772	EPSD;PhosphoSitePlus	COSMIC	10.658	Down-regulation
Atypical_PIKK_ATR_ATR_ST	P38398	BRCA1	Q13535	ATR	S1524	L1517V	1517	Missense	distal	-7	no	16.882	16.992	EPSD;PhosphoSitePlus	COSMIC	10.658	Up-regulation
Atypical_PIKK_ATR_ATR_ST	P38398	BRCA1	Q13535	ATR	S1524	L1517P	1517	Missense	distal	-7	no	16.882	17.075	EPSD;PhosphoSitePlus	COSMIC	10.658	Up-regulation
Atypical_PIKK_ATR_ATR_ST	P38398	BRCA1	Q13535	ATR	S1524	P1523L	1523	Missense	proximal	-1	no	16.882	16.903	EPSD;PhosphoSitePlus	COSMIC	10.658	Up-regulation
Atypical_PIKK_ATR_ATR_ST	P38398	BRCA1	Q13535	ATR	S1595	R1589C	1589	Missense	distal	-6	no	12.461	12.448	EPSD	COSMIC;CCLE	10.658	Down-regulation
Atypical_PIKK_ATR_ATR_ST	P38398	BRCA1	Q13535	ATR	S1595	S1595F	1595	Missense	central	0	yes	12.461	0.000	EPSD	COSMIC	10.658	Loss
Atypical_PIKK_ATR_ATR_ST	P38398	BRCA1	Q13535	ATR	S1595	R1589H	1589	Missense	distal	-6	no	12.461	12.467	EPSD	COSMIC	10.658	Up-regulation
Atypical_PIKK_ATR_ATR_ST	P38398	BRCA1	Q13535	ATR	S1595	S1598P	1598	Missense	distal	3	no	12.461	12.397	EPSD	COSMIC	10.658	Down-regulation
Atypical_PIKK_ATR_ATR_ST	P38398	BRCA1	Q13535	ATR	S1651	M1652I	1652	Missense	proximal	1	no	11.246	7.841	EPSD	COSMIC	10.658	Loss
Atypical_PIKK_ATR_ATR_ST	P38398	BRCA1	Q13535	ATR	S1651	R1645T	1645	Missense	distal	-6	no	11.246	11.249	EPSD	COSMIC	10.658	Up-regulation
Atypical_PIKK_ATR_ATR_ST	P38398	BRCA1	Q13535	ATR	S1651	R1645M	1645	Missense	distal	-6	no	11.246	11.228	EPSD	COSMIC	10.658	Down-regulation
Atypical_PIKK_ATR_ATR_ST	P38398	BRCA1	Q13535	ATR	S1651	S1651F	1651	Missense	central	0	yes	11.246	0.000	EPSD	COSMIC	10.658	Loss
Atypical_PIKK_ATR_ATR_ST	P38398	BRCA1	Q13535	ATR	S1651	R1645S	1645	Missense	distal	-6	no	11.246	11.163	EPSD	COSMIC	10.658	Down-regulation
Atypical_PIKK_ATR_ATR_ST	P38398	BRCA1	Q13535	ATR	S1651	R1649T	1649	Missense	proximal	-2	no	11.246	11.138	EPSD	COSMIC	10.658	Down-regulation
Atypical_PIKK_ATR_ATR_ST	P38398	BRCA1	Q13535	ATR	S1651	V1654E	1654	Missense	distal	3	no	11.246	10.832	EPSD	COSMIC	10.658	Down-regulation
Atypical_PIKK_ATR_ATR_ST	P38398	BRCA1	Q13535	ATR	S1651	R1649I	1649	Missense	proximal	-2	no	11.246	11.333	EPSD	COSMIC	10.658	Up-regulation
Atypical_PIKK_ATR_ATR_ST	P38398	BRCA1	Q13535	ATR	S1651	V1653A	1653	Missense	proximal	2	no	11.246	10.756	EPSD	COSMIC	10.658	Down-regulation
Atypical_PIKK_ATR_ATR_ST	P38398	BRCA1	Q13535	ATR	S1651	R1649K	1649	Missense	proximal	-2	no	11.246	11.232	EPSD	COSMIC	10.658	Down-regulation
Atypical_PIKK_ATR_ATR_ST	P38398	BRCA1	Q13535	ATR	S1651	V1654M	1654	Missense	distal	3	no	11.246	10.455	EPSD	COSMIC	10.658	Loss
Atypical_PIKK_ATR_ATR_ST	P38398	BRCA1	Q13535	ATR	T1658	P1659Q	1659	Missense	proximal	1	no	9.305	14.173	EPSD	COSMIC	10.658	Gain
Atypical_PIKK_ATR_ATR_ST	P38398	BRCA1	Q13535	ATR	T1658	V1654E	1654	Missense	distal	-4	no	9.305	10.787	EPSD	COSMIC	10.658	Gain
Atypical_PIKK_ATR_ATR_ST	P38398	BRCA1	Q13535	ATR	T1720	Q1721R	1721	Missense	proximal	1	no	11.917	4.922	EPSD	COSMIC	10.658	Loss
Atypical_PIKK_ATR_ATR_ST	P38398	BRCA1	Q13535	ATR	T1720	T1720I	1720	Missense	central	0	yes	11.917	0.000	EPSD	COSMIC	10.658	Loss
Atypical_PIKK_ATR_ATR_ST	P38398	BRCA1	Q13535	ATR	T1720	S1722F	1722	Missense	proximal	2	no	11.917	9.229	EPSD	COSMIC	10.658	Loss
Atypical_PIKK_ATR_ATR_ST	P38398	BRCA1	Q13535	ATR	T1720	R1726T	1726	Missense	distal	6	no	11.917	12.266	EPSD	COSMIC	10.658	Up-regulation
Atypical_PIKK_ATR_ATR_ST	P38398	BRCA1	Q13535	ATR	T1720	W1718L	1718	Missense	proximal	-2	no	11.917	12.104	EPSD	COSMIC	10.658	Up-regulation
Atypical_PIKK_ATR_ATR_ST	P38398	BRCA1	Q13535	ATR	T1720	I1723V	1723	Missense	distal	3	no	11.917	12.008	EPSD	COSMIC	10.658	Up-regulation
Atypical_PIKK_ATR_ATR_ST	P38398	BRCA1	Q13535	ATR	T1720	V1713A	1713	Missense	distal	-7	no	11.917	11.938	EPSD	COSMIC	10.658	Up-regulation
Atypical_PIKK_ATR_ATR_ST	P38398	BRCA1	Q13535	ATR	T1720	T1720A	1720	Missense	central	0	yes	11.917	0.000	EPSD	COSMIC	10.658	Loss
Atypical_PIKK_ATR_ATR_ST	P38398	BRCA1	Q13535	ATR	T1720	V1719M	1719	Missense	proximal	-1	no	11.917	12.067	EPSD	COSMIC	10.658	Up-regulation
Atypical_PIKK_ATR_ATR_ST	P38398	BRCA1	Q13535	ATR	T1720	E1725K	1725	Missense	distal	5	no	11.917	11.926	EPSD	COSMIC	10.658	Up-regulation
Atypical_PIKK_ATR_ATR_ST	Q9Y248	GINS2	Q13535	ATR	S182	S182C	182	Missense	central	0	yes	11.861	0.000	PhosphoSitePlus	COSMIC	10.658	Loss
Atypical_PIKK_ATR_ATR_ST	Q9Y248	GINS2	Q13535	ATR	S182	Q181E	181	Missense	proximal	-1	no	11.861	11.946	PhosphoSitePlus	COSMIC	10.658	Up-regulation
Atypical_PIKK_ATR_ATR_ST	O43543	XRCC2	Q13535	ATR	T12	E13Q	13	Missense	proximal	1	no	7.851	13.771	EPSD	COSMIC	10.658	Gain
Atypical_PIKK_ATR_ATR_ST	O43543	XRCC2	Q13535	ATR	S247	S242F	242	Missense	distal	-5	no	14.696	14.922	PhosphoSitePlus	COSMIC	10.658	Up-regulation
Atypical_PIKK_ATR_ATR_ST	O43543	XRCC2	Q13535	ATR	S262	C259Y	259	Missense	distal	-3	no	11.284	11.709	EPSD	COSMIC	10.658	Up-regulation
Atypical_PIKK_ATR_ATR_ST	O43543	XRCC2	Q13535	ATR	S262	V256G	256	Missense	distal	-6	no	11.284	11.237	EPSD	COSMIC	10.658	Down-regulation
Atypical_PIKK_ATR_ATR_ST	Q9UBU7	DBF4	Q13535	ATR	S381	H379N	379	Missense	proximal	-2	no	12.738	13.623	EPSD	COSMIC	10.658	Up-regulation
Atypical_PIKK_ATR_ATR_ST	Q9UBU7	DBF4	Q13535	ATR	T449	L453E	453	Missense	distal	4	no	15.505	15.026	EPSD;PhosphoSitePlus	COSMIC	10.658	Down-regulation
Atypical_PIKK_ATR_ATR_ST	Q9UBU7	DBF4	Q13535	ATR	S502	P504S	504	Missense	proximal	2	no	18.004	17.688	PhosphoSitePlus;EPSD	COSMIC	10.658	Down-regulation
Atypical_PIKK_ATR_ATR_ST	Q9UBU7	DBF4	Q13535	ATR	S539	S538R	538	Missense	proximal	-1	no	16.416	16.543	EPSD;PhosphoSitePlus	COSMIC	10.658	Up-regulation
Atypical_PIKK_ATR_ATR_ST	Q9UBU7	DBF4	Q13535	ATR	S613	D620N	620	Missense	distal	7	no	10.557	10.781	EPSD	COSMIC	10.658	Gain
Atypical_PIKK_ATR_ATR_ST	Q9UBU7	DBF4	Q13535	ATR	T638	C644W	644	Missense	distal	6	no	10.923	10.809	EPSD	COSMIC	10.658	Down-regulation
Atypical_PIKK_ATR_ATR_ST	Q9UBU7	DBF4	Q13535	ATR	T638	S636G	636	Missense	proximal	-2	no	10.923	11.236	EPSD	COSMIC;GDSC;CCLE	10.658	Up-regulation
Atypical_PIKK_ATR_ATR_ST	Q9Y285	FARSA	Q13535	ATR	S109	F104C	104	Missense	distal	-5	no	12.493	12.456	EPSD	COSMIC	10.658	Down-regulation
Atypical_PIKK_ATR_ATR_ST	Q9Y285	FARSA	Q13535	ATR	S109	R114W	114	Missense	distal	5	no	12.493	12.494	EPSD	COSMIC	10.658	Up-regulation
Atypical_PIKK_ATR_ATR_ST	Q9Y285	FARSA	Q13535	ATR	S109	R114Q	114	Missense	distal	5	no	12.493	12.484	EPSD	COSMIC	10.658	Down-regulation
Atypical_PIKK_ATR_ATR_ST	Q9Y285	FARSA	Q13535	ATR	S193	Q188P	188	Missense	distal	-5	no	11.853	11.794	EPSD	COSMIC	10.658	Down-regulation
Atypical_PIKK_ATR_ATR_ST	Q9Y285	FARSA	Q13535	ATR	S301	G306D	306	Missense	distal	5	no	16.862	16.866	PhosphoSitePlus	COSMIC	10.658	Up-regulation
Atypical_PIKK_ATR_ATR_ST	Q9Y285	FARSA	Q13535	ATR	S301	R295L	295	Missense	distal	-6	no	16.862	16.890	PhosphoSitePlus	COSMIC	10.658	Up-regulation
Atypical_PIKK_ATR_ATR_ST	Q9Y285	FARSA	Q13535	ATR	S301	R298W	298	Missense	distal	-3	no	16.862	17.226	PhosphoSitePlus	COSMIC	10.658	Up-regulation
Atypical_PIKK_ATR_ATR_ST	Q9Y285	FARSA	Q13535	ATR	S307	G306D	306	Missense	proximal	-1	no	14.382	14.476	EPSD	COSMIC	10.658	Up-regulation
Atypical_PIKK_ATR_ATR_ST	Q9Y285	FARSA	Q13535	ATR	T504	A507T	507	Missense	distal	3	no	10.949	11.261	EPSD	COSMIC	10.658	Up-regulation
Atypical_PIKK_ATR_ATR_ST	Q8IYD8	FANCM	Q13535	ATR	T247	A254V	254	Missense	distal	7	no	11.031	11.171	EPSD	COSMIC	10.658	Up-regulation
Atypical_PIKK_ATR_ATR_ST	Q8IYD8	FANCM	Q13535	ATR	T477	R478Q	478	Missense	proximal	1	no	8.753	15.749	EPSD	COSMIC	10.658	Gain
Atypical_PIKK_ATR_ATR_ST	Q8IYD8	FANCM	Q13535	ATR	S832	S827Y	827	Missense	distal	-5	no	11.894	12.222	EPSD	COSMIC	10.658	Up-regulation
Atypical_PIKK_ATR_ATR_ST	Q8IYD8	FANCM	Q13535	ATR	S832	S827F	827	Missense	distal	-5	no	11.894	12.121	EPSD	COSMIC	10.658	Up-regulation
Atypical_PIKK_ATR_ATR_ST	Q8IYD8	FANCM	Q13535	ATR	S995	P999L	999	Missense	distal	4	no	10.567	10.717	EPSD	COSMIC	10.658	Gain
Atypical_PIKK_ATR_ATR_ST	Q8IYD8	FANCM	Q13535	ATR	S1045	S1039L	1039	Missense	distal	-6	no	11.722	11.831	PhosphoSitePlus	COSMIC	10.658	Up-regulation
Atypical_PIKK_ATR_ATR_ST	Q8IYD8	FANCM	Q13535	ATR	S1045	L1049F	1049	Missense	distal	4	no	11.722	11.503	PhosphoSitePlus	COSMIC	10.658	Down-regulation
Atypical_PIKK_ATR_ATR_ST	Q8IYD8	FANCM	Q13535	ATR	S1045	S1045Y	1045	Missense	central	0	yes	11.722	0.000	PhosphoSitePlus	COSMIC	10.658	Loss
Atypical_PIKK_ATR_ATR_ST	Q8IYD8	FANCM	Q13535	ATR	S1045	Q1047H	1047	Missense	proximal	2	no	11.722	11.401	PhosphoSitePlus	COSMIC	10.658	Down-regulation
Atypical_PIKK_ATR_ATR_ST	Q8IYD8	FANCM	Q13535	ATR	S1045	S1045F	1045	Missense	central	0	yes	11.722	0.000	PhosphoSitePlus	COSMIC	10.658	Loss
Atypical_PIKK_ATR_ATR_ST	Q8IYD8	FANCM	Q13535	ATR	S1045	L1051V	1051	Missense	distal	6	no	11.722	11.833	PhosphoSitePlus	COSMIC	10.658	Up-regulation
Atypical_PIKK_ATR_ATR_ST	Q8IYD8	FANCM	Q13535	ATR	S1437	S1437Y	1437	Missense	central	0	yes	11.242	0.000	EPSD	COSMIC	10.658	Loss
Atypical_PIKK_ATR_ATR_ST	Q8IYD8	FANCM	Q13535	ATR	S1836	H1841R	1841	Missense	distal	5	no	11.868	11.874	EPSD	COSMIC	10.658	Up-regulation
Atypical_PIKK_ATR_ATR_ST	Q8IYD8	FANCM	Q13535	ATR	S1836	S1829C	1829	Missense	distal	-7	no	11.868	11.643	EPSD	COSMIC	10.658	Down-regulation
Atypical_PIKK_ATR_ATR_ST	Q8IYD8	FANCM	Q13535	ATR	S2004	A2001T	2001	Missense	distal	-3	no	10.663	10.102	EPSD	COSMIC	10.658	Loss
Atypical_PIKK_ATR_ATR_ST	Q8IYD8	FANCM	Q13535	ATR	S2004	R1999G	1999	Missense	distal	-5	no	10.663	10.497	EPSD	COSMIC;GDSC;CCLE	10.658	Loss
Atypical_PIKK_ATR_ATR_ST	Q8IYD8	FANCM	Q13535	ATR	S2004	S2009Y	2009	Missense	distal	5	no	10.663	10.685	EPSD	COSMIC	10.658	Up-regulation
Atypical_PIKK_ATR_ATR_ST	P27707	DCK	Q13535	ATR	S15	A14V	14	Missense	proximal	-1	no	11.612	11.355	EPSD	COSMIC;CCLE	10.658	Down-regulation
Atypical_PIKK_ATR_ATR_ST	Q9BXW9	FANCD2	Q13535	ATR	S15	E14D	14	Missense	proximal	-1	no	13.481	13.526	EPSD	COSMIC	10.658	Up-regulation
Atypical_PIKK_ATR_ATR_ST	Q9BXW9	FANCD2	Q13535	ATR	S319	R315Q	315	Missense	distal	-4	no	15.682	15.864	EPSD	COSMIC;GDSC;CCLE	10.658	Up-regulation
Atypical_PIKK_ATR_ATR_ST	Q9BXW9	FANCD2	Q13535	ATR	S319	Q320K	320	Missense	proximal	1	no	15.682	4.716	EPSD	COSMIC	10.658	Loss
Atypical_PIKK_ATR_ATR_ST	Q9BXW9	FANCD2	Q13535	ATR	S319	R315W	315	Missense	distal	-4	no	15.682	16.140	EPSD	COSMIC	10.658	Up-regulation
Atypical_PIKK_ATR_ATR_ST	Q9BXW9	FANCD2	Q13535	ATR	T596	R599T	599	Missense	distal	3	no	14.160	14.246	EPSD;PhosphoSitePlus	COSMIC	10.658	Up-regulation
Atypical_PIKK_ATR_ATR_ST	Q9BXW9	FANCD2	Q13535	ATR	T596	S603C	603	Missense	distal	7	no	14.160	14.522	EPSD;PhosphoSitePlus	COSMIC	10.658	Up-regulation
Atypical_PIKK_ATR_ATR_ST	Q9BXW9	FANCD2	Q13535	ATR	T608	C607F	607	Missense	proximal	-1	no	17.179	16.630	EPSD;PhosphoSitePlus	COSMIC	10.658	Down-regulation
Atypical_PIKK_ATR_ATR_ST	Q9BXW9	FANCD2	Q13535	ATR	T608	S603C	603	Missense	distal	-5	no	17.179	17.368	EPSD;PhosphoSitePlus	COSMIC	10.658	Up-regulation
Atypical_PIKK_ATR_ATR_ST	Q9BXW9	FANCD2	Q13535	ATR	T691	G685E	685	Missense	distal	-6	no	15.569	15.595	EPSD;PhosphoSitePlus	COSMIC	10.658	Up-regulation
Atypical_PIKK_ATR_ATR_ST	Q9BXW9	FANCD2	Q13535	ATR	T691	D690N	690	Missense	proximal	-1	no	15.569	15.859	EPSD;PhosphoSitePlus	COSMIC;GDSC	10.658	Up-regulation
Atypical_PIKK_ATR_ATR_ST	Q9BXW9	FANCD2	Q13535	ATR	S717	P714L	714	Missense	distal	-3	no	17.875	18.170	PhosphoSitePlus;EPSD	COSMIC	10.658	Up-regulation
Atypical_PIKK_ATR_ATR_ST	Q9BXW9	FANCD2	Q13535	ATR	S717	G713D	713	Missense	distal	-4	no	17.875	19.225	PhosphoSitePlus;EPSD	COSMIC	10.658	Up-regulation
Atypical_PIKK_ATR_ATR_ST	Q9BXW9	FANCD2	Q13535	ATR	S886	S881F	881	Missense	distal	-5	no	10.866	11.092	EPSD	COSMIC	10.658	Up-regulation
Atypical_PIKK_ATR_ATR_ST	Q9BXW9	FANCD2	Q13535	ATR	S1096	R1097Q	1097	Missense	proximal	1	no	5.660	12.656	EPSD	COSMIC;GDSC;CCLE	10.658	Gain
Atypical_PIKK_ATR_ATR_ST	Q9BXW9	FANCD2	Q13535	ATR	S1257	A1254S	1254	Missense	distal	-3	no	14.367	13.527	EPSD	COSMIC	10.658	Down-regulation
Atypical_PIKK_ATR_ATR_ST	Q9BXW9	FANCD2	Q13535	ATR	S1418	S1417P	1417	Missense	proximal	-1	no	14.007	14.222	EPSD	COSMIC	10.658	Up-regulation
Atypical_PIKK_ATR_ATR_ST	Q9BXW9	FANCD2	Q13535	ATR	S1418	S1412G	1412	Missense	distal	-6	no	14.007	14.037	EPSD	COSMIC	10.658	Up-regulation
Atypical_PIKK_ATR_ATR_ST	Q9BXW9	FANCD2	Q13535	ATR	S1418	S1412N	1412	Missense	distal	-6	no	14.007	14.073	EPSD	COSMIC	10.658	Up-regulation
Atypical_PIKK_ATR_ATR_ST	Q9BXW9	FANCD2	Q13535	ATR	S1443	D1449V	1449	Missense	distal	6	no	10.977	11.053	EPSD	COSMIC	10.658	Up-regulation
Atypical_PIKK_ATR_ATR_ST	Q9BXW9	FANCD2	Q13535	ATR	S1443	G1437A	1437	Missense	distal	-6	no	10.977	11.054	EPSD	COSMIC	10.658	Up-regulation
Atypical_PIKK_ATR_ATR_ST	P06748	NPM1	Q13535	ATR	S10	R13S	13	Missense	distal	3	no	10.443	10.878	EPSD	COSMIC	10.658	Gain
Atypical_PIKK_ATR_ATR_ST	P06748	NPM1	Q13535	ATR	S43	S48T	48	Missense	distal	5	no	12.372	12.380	EPSD	COSMIC	10.658	Up-regulation
Atypical_PIKK_ATR_ATR_ST	P06748	NPM1	Q13535	ATR	S125	S125L	125	Missense	central	0	yes	14.864	0.000	PhosphoSitePlus	COSMIC	10.658	Loss
Atypical_PIKK_ATR_ATR_ST	P06748	NPM1	Q13535	ATR	S125	E129Q	129	Missense	distal	4	no	14.864	14.992	PhosphoSitePlus	COSMIC	10.658	Up-regulation
Atypical_PIKK_ATR_ATR_ST	P06748	NPM1	Q13535	ATR	S125	D127N	127	Missense	proximal	2	no	14.864	15.785	PhosphoSitePlus	COSMIC	10.658	Up-regulation
Atypical_PIKK_ATR_ATR_ST	P06748	NPM1	Q13535	ATR	T199	P200S	200	Missense	proximal	1	no	10.691	9.581	EPSD	COSMIC	10.658	Loss
Atypical_PIKK_ATR_ATR_ST	P06748	NPM1	Q13535	ATR	T199	S195F	195	Missense	distal	-4	no	10.691	10.407	EPSD	COSMIC	10.658	Loss
Atypical_PIKK_ATR_ATR_ST	P15927	RPA2	Q13535	ATR	S12	Y14N	14	Missense	proximal	2	no	9.256	11.849	EPSD	COSMIC	10.658	Gain
Atypical_PIKK_ATR_ATR_ST	P15927	RPA2	Q13535	ATR	T21	Y14N	14	Missense	distal	-7	no	16.057	16.096	EPSD;PhosphoSitePlus	COSMIC	10.658	Up-regulation
Atypical_PIKK_ATR_ATR_ST	P15927	RPA2	Q13535	ATR	S33	Q34K	34	Missense	proximal	1	no	17.862	6.895	PhosphoSitePlus;EPSD	COSMIC	10.658	Loss
Atypical_PIKK_ATR_ATR_ST	P15927	RPA2	Q13535	ATR	S33	K37N	37	Missense	distal	4	no	17.862	18.630	PhosphoSitePlus;EPSD	COSMIC	10.658	Up-regulation
Atypical_PIKK_ATR_ATR_ST	P15927	RPA2	Q13535	ATR	S52	S56F	56	Missense	distal	4	no	14.938	14.957	EPSD;PhosphoSitePlus	COSMIC	10.658	Up-regulation
Atypical_PIKK_ATR_ATR_ST	P15927	RPA2	Q13535	ATR	S52	S52F	52	Missense	central	0	yes	14.938	0.000	EPSD;PhosphoSitePlus	COSMIC	10.658	Loss
Atypical_PIKK_ATR_ATR_ST	P15927	RPA2	Q13535	ATR	S52	L59F	59	Missense	distal	7	no	14.938	14.838	EPSD;PhosphoSitePlus	COSMIC	10.658	Down-regulation
Atypical_PIKK_ATR_ATR_ST	P15927	RPA2	Q13535	ATR	S72	Q73H	73	Missense	proximal	1	no	15.886	-1.632	EPSD;PhosphoSitePlus	COSMIC	10.658	Loss
Atypical_PIKK_ATR_ATR_ST	P15927	RPA2	Q13535	ATR	S114	W107L	107	Missense	distal	-7	no	12.522	12.463	EPSD	COSMIC	10.658	Down-regulation
Atypical_PIKK_ATR_ATR_ST	P15927	RPA2	Q13535	ATR	S114	W107C	107	Missense	distal	-7	no	12.522	12.403	EPSD	COSMIC	10.658	Down-regulation
Atypical_PIKK_ATR_ATR_ST	P15927	RPA2	Q13535	ATR	S174	P176S	176	Missense	proximal	2	no	14.923	14.607	EPSD;PhosphoSitePlus	COSMIC	10.658	Down-regulation
Atypical_PIKK_ATR_ATR_ST	Q9NZC9	SMARCAL1	Q13535	ATR	S2	L5R	5	Missense	distal	3	no	10.616	10.847	EPSD	COSMIC	10.658	Gain
Atypical_PIKK_ATR_ATR_ST	Q9NZC9	SMARCAL1	Q13535	ATR	S115	I122F	122	Missense	distal	7	no	11.322	11.064	EPSD	COSMIC	10.658	Down-regulation
Atypical_PIKK_ATR_ATR_ST	Q9NZC9	SMARCAL1	Q13535	ATR	S129	I122F	122	Missense	distal	-7	no	11.361	11.370	EPSD	COSMIC	10.658	Up-regulation
Atypical_PIKK_ATR_ATR_ST	Q9NZC9	SMARCAL1	Q13535	ATR	S173	P166L	166	Missense	distal	-7	no	13.969	13.776	EPSD	COSMIC	10.658	Down-regulation
Atypical_PIKK_ATR_ATR_ST	Q9NZC9	SMARCAL1	Q13535	ATR	S627	L633M	633	Missense	distal	6	no	11.757	11.641	EPSD	COSMIC;GDSC;CCLE	10.658	Down-regulation
Atypical_PIKK_ATR_ATR_ST	Q9NZC9	SMARCAL1	Q13535	ATR	S652	R645H	645	Missense	distal	-7	no	14.972	15.024	PhosphoSitePlus	COSMIC	10.658	Up-regulation
Atypical_PIKK_ATR_ATR_ST	Q9NZC9	SMARCAL1	Q13535	ATR	T914	S912T	912	Missense	proximal	-2	no	10.505	10.807	EPSD	COSMIC	10.658	Gain
Atypical_PIKK_ATR_ATR_ST	Q9NZC9	SMARCAL1	Q13535	ATR	S919	S912T	912	Missense	distal	-7	no	11.858	11.801	EPSD	COSMIC	10.658	Down-regulation
Atypical_PIKK_ATR_ATR_ST	Q14683	SMC1A	Q13535	ATR	S85	R92G	92	Missense	distal	7	no	11.105	10.848	EPSD	COSMIC	10.658	Down-regulation
Atypical_PIKK_ATR_ATR_ST	Q14683	SMC1A	Q13535	ATR	S85	A78T	78	Missense	distal	-7	no	11.105	11.082	EPSD	COSMIC	10.658	Down-regulation
Atypical_PIKK_ATR_ATR_ST	Q14683	SMC1A	Q13535	ATR	S358	R363T	363	Missense	distal	5	no	15.528	15.526	EPSD	COSMIC	10.658	Down-regulation
Atypical_PIKK_ATR_ATR_ST	Q14683	SMC1A	Q13535	ATR	S360	T366A	366	Missense	distal	6	no	13.881	13.603	EPSD	COSMIC	10.658	Down-regulation
Atypical_PIKK_ATR_ATR_ST	Q14683	SMC1A	Q13535	ATR	S360	R363T	363	Missense	distal	3	no	13.881	13.968	EPSD	COSMIC	10.658	Up-regulation
Atypical_PIKK_ATR_ATR_ST	Q14683	SMC1A	Q13535	ATR	S448	K453M	453	Missense	distal	5	no	12.018	12.023	EPSD	COSMIC	10.658	Up-regulation
Atypical_PIKK_ATR_ATR_ST	Q14683	SMC1A	Q13535	ATR	S448	L455P	455	Missense	distal	7	no	12.018	12.019	EPSD	COSMIC	10.658	Up-regulation
Atypical_PIKK_ATR_ATR_ST	Q14683	SMC1A	Q13535	ATR	S448	S448F	448	Missense	central	0	yes	12.018	0.000	EPSD	COSMIC	10.658	Loss
Atypical_PIKK_ATR_ATR_ST	Q14683	SMC1A	Q13535	ATR	S703	S703F	703	Missense	central	0	yes	14.499	0.000	EPSD	COSMIC	10.658	Loss
Atypical_PIKK_ATR_ATR_ST	Q14683	SMC1A	Q13535	ATR	S703	G707V	707	Missense	distal	4	no	14.499	13.893	EPSD	COSMIC	10.658	Down-regulation
Atypical_PIKK_ATR_ATR_ST	Q14683	SMC1A	Q13535	ATR	S703	A705V	705	Missense	proximal	2	no	14.499	14.989	EPSD	COSMIC;GDSC;CCLE	10.658	Up-regulation
Atypical_PIKK_ATR_ATR_ST	Q14683	SMC1A	Q13535	ATR	S703	R699H	699	Missense	distal	-4	no	14.499	14.501	EPSD	COSMIC	10.658	Up-regulation
Atypical_PIKK_ATR_ATR_ST	Q14683	SMC1A	Q13535	ATR	S715	E720K	720	Missense	distal	5	no	12.596	12.605	EPSD	COSMIC	10.658	Up-regulation
Atypical_PIKK_ATR_ATR_ST	Q14683	SMC1A	Q13535	ATR	S951	S957F	957	Missense	distal	6	no	15.340	15.182	EPSD	COSMIC	10.658	Down-regulation
Atypical_PIKK_ATR_ATR_ST	Q14683	SMC1A	Q13535	ATR	S951	D949Y	949	Missense	proximal	-2	no	15.340	15.787	EPSD	COSMIC	10.658	Up-regulation
Atypical_PIKK_ATR_ATR_ST	Q14683	SMC1A	Q13535	ATR	S957	S957F	957	Missense	central	0	yes	17.580	0.000	PhosphoSitePlus;EPSD	COSMIC	10.658	Loss
Atypical_PIKK_ATR_ATR_ST	Q14683	SMC1A	Q13535	ATR	S966	S971G	971	Missense	distal	5	no	16.361	16.366	EPSD;PhosphoSitePlus	COSMIC	10.658	Up-regulation
Atypical_PIKK_ATR_ATR_ST	Q14683	SMC1A	Q13535	ATR	S1188	V1186L	1186	Missense	proximal	-2	no	11.903	12.350	EPSD	COSMIC	10.658	Up-regulation
Atypical_PIKK_ATR_ATR_ST	P54132	BLM	Q13535	ATR	T20	L27F	27	Missense	distal	7	no	10.871	10.771	EPSD	COSMIC	10.658	Down-regulation
Atypical_PIKK_ATR_ATR_ST	P54132	BLM	Q13535	ATR	S43	T41A	41	Missense	proximal	-2	no	10.361	10.835	EPSD	COSMIC	10.658	Gain
Atypical_PIKK_ATR_ATR_ST	P54132	BLM	Q13535	ATR	S43	S42Y	42	Missense	proximal	-1	no	10.361	10.693	EPSD	COSMIC	10.658	Gain
Atypical_PIKK_ATR_ATR_ST	P54132	BLM	Q13535	ATR	T50	V54I	54	Missense	distal	4	no	10.239	10.759	EPSD	COSMIC	10.658	Gain
Atypical_PIKK_ATR_ATR_ST	P54132	BLM	Q13535	ATR	T99	G102D	102	Missense	distal	3	no	15.027	15.097	EPSD;PhosphoSitePlus	COSMIC	10.658	Up-regulation
Atypical_PIKK_ATR_ATR_ST	P54132	BLM	Q13535	ATR	T99	G96V	96	Missense	distal	-3	no	15.027	15.427	EPSD;PhosphoSitePlus	COSMIC	10.658	Up-regulation
Atypical_PIKK_ATR_ATR_ST	P54132	BLM	Q13535	ATR	T99	R101T	101	Missense	proximal	2	no	15.027	14.910	EPSD;PhosphoSitePlus	COSMIC	10.658	Down-regulation
Atypical_PIKK_ATR_ATR_ST	P54132	BLM	Q13535	ATR	T99	S104L	104	Missense	distal	5	no	15.027	15.034	EPSD;PhosphoSitePlus	COSMIC	10.658	Up-regulation
Atypical_PIKK_ATR_ATR_ST	P54132	BLM	Q13535	ATR	T99	N92D	92	Missense	distal	-7	no	15.027	15.145	EPSD;PhosphoSitePlus	COSMIC;GDSC	10.658	Up-regulation
Atypical_PIKK_ATR_ATR_ST	P54132	BLM	Q13535	ATR	T114	F111V	111	Missense	distal	-3	no	12.221	11.802	EPSD	COSMIC	10.658	Down-regulation
Atypical_PIKK_ATR_ATR_ST	P54132	BLM	Q13535	ATR	T114	P109L	109	Missense	distal	-5	no	12.221	12.374	EPSD	COSMIC	10.658	Up-regulation
Atypical_PIKK_ATR_ATR_ST	P54132	BLM	Q13535	ATR	T114	P109S	109	Missense	distal	-5	no	12.221	12.192	EPSD	COSMIC	10.658	Down-regulation
Atypical_PIKK_ATR_ATR_ST	P54132	BLM	Q13535	ATR	T114	V118I	118	Missense	distal	4	no	12.221	12.741	EPSD	COSMIC	10.658	Up-regulation
Atypical_PIKK_ATR_ATR_ST	P54132	BLM	Q13535	ATR	T114	D110Y	110	Missense	distal	-4	no	12.221	8.994	EPSD	COSMIC	10.658	Loss
Atypical_PIKK_ATR_ATR_ST	P54132	BLM	Q13535	ATR	T114	P115L	115	Missense	proximal	1	no	12.221	11.655	EPSD	COSMIC	10.658	Down-regulation
Atypical_PIKK_ATR_ATR_ST	P54132	BLM	Q13535	ATR	T114	E117K	117	Missense	distal	3	no	12.221	12.378	EPSD	COSMIC	10.658	Up-regulation
Atypical_PIKK_ATR_ATR_ST	P54132	BLM	Q13535	ATR	T114	L107S	107	Missense	distal	-7	no	12.221	12.386	EPSD	COSMIC	10.658	Up-regulation
Atypical_PIKK_ATR_ATR_ST	P54132	BLM	Q13535	ATR	T122	V118I	118	Missense	distal	-4	no	14.365	13.491	PhosphoSitePlus;EPSD	COSMIC	10.658	Down-regulation
Atypical_PIKK_ATR_ATR_ST	P54132	BLM	Q13535	ATR	T122	P126S	126	Missense	distal	4	no	14.365	14.278	PhosphoSitePlus;EPSD	COSMIC	10.658	Down-regulation
Atypical_PIKK_ATR_ATR_ST	P54132	BLM	Q13535	ATR	T122	P115L	115	Missense	distal	-7	no	14.365	14.172	PhosphoSitePlus;EPSD	COSMIC	10.658	Down-regulation
Atypical_PIKK_ATR_ATR_ST	P54132	BLM	Q13535	ATR	T122	E117K	117	Missense	distal	-5	no	14.365	14.446	PhosphoSitePlus;EPSD	COSMIC	10.658	Up-regulation
Atypical_PIKK_ATR_ATR_ST	P54132	BLM	Q13535	ATR	S314	S315Y	315	Missense	proximal	1	no	11.794	11.458	EPSD	COSMIC	10.658	Down-regulation
Atypical_PIKK_ATR_ATR_ST	P54132	BLM	Q13535	ATR	S314	C318S	318	Missense	distal	4	no	11.794	11.105	EPSD	COSMIC;GDSC;CCLE	10.658	Down-regulation
Atypical_PIKK_ATR_ATR_ST	P54132	BLM	Q13535	ATR	S449	T446I	446	Missense	distal	-3	no	11.788	11.534	EPSD	COSMIC	10.658	Down-regulation
Atypical_PIKK_ATR_ATR_ST	P54132	BLM	Q13535	ATR	S706	S706F	706	Missense	central	0	yes	13.852	0.000	EPSD	COSMIC	10.658	Loss
Atypical_PIKK_ATR_ATR_ST	P54132	BLM	Q13535	ATR	T907	M904K	904	Missense	distal	-3	no	12.034	11.944	EPSD	COSMIC	10.658	Down-regulation
Atypical_PIKK_ATR_ATR_ST	P54132	BLM	Q13535	ATR	T907	C901Y	901	Missense	distal	-6	no	12.034	12.138	EPSD	COSMIC	10.658	Up-regulation
Atypical_PIKK_ATR_ATR_ST	P54132	BLM	Q13535	ATR	S1138	R1139Q	1139	Missense	proximal	1	no	4.982	11.978	EPSD	COSMIC;CCLE	10.658	Gain
Atypical_PIKK_ATR_ATR_ST	P54132	BLM	Q13535	ATR	S1197	V1198M	1198	Missense	proximal	1	no	-4.219	11.391	EPSD	COSMIC;GDSC	10.658	Gain
Atypical_PIKK_ATR_ATR_ST	P54132	BLM	Q13535	ATR	S1304	S1302F	1302	Missense	proximal	-2	no	13.149	13.747	EPSD	COSMIC	10.658	Up-regulation
Atypical_PIKK_ATR_ATR_ST	Q8IX01	SUGP2	Q13535	ATR	S59	D60N	60	Missense	proximal	1	no	10.859	11.997	EPSD	COSMIC	10.658	Up-regulation
Atypical_PIKK_ATR_ATR_ST	Q8IX01	SUGP2	Q13535	ATR	S59	L65F	65	Missense	distal	6	no	10.859	10.925	EPSD	COSMIC	10.658	Up-regulation
Atypical_PIKK_ATR_ATR_ST	Q8IX01	SUGP2	Q13535	ATR	S93	P95S	95	Missense	proximal	2	no	12.289	11.973	EPSD	COSMIC	10.658	Down-regulation
Atypical_PIKK_ATR_ATR_ST	Q8IX01	SUGP2	Q13535	ATR	S93	S93R	93	Missense	central	0	yes	12.289	0.000	EPSD	COSMIC	10.658	Loss
Atypical_PIKK_ATR_ATR_ST	Q8IX01	SUGP2	Q13535	ATR	S93	P88H	88	Missense	distal	-5	no	12.289	12.379	EPSD	COSMIC	10.658	Up-regulation
Atypical_PIKK_ATR_ATR_ST	Q8IX01	SUGP2	Q13535	ATR	S93	R91K	91	Missense	proximal	-2	no	12.289	12.275	EPSD	COSMIC	10.658	Down-regulation
Atypical_PIKK_ATR_ATR_ST	Q8IX01	SUGP2	Q13535	ATR	S98	P95S	95	Missense	distal	-3	no	10.961	10.685	EPSD	COSMIC	10.658	Down-regulation
Atypical_PIKK_ATR_ATR_ST	Q8IX01	SUGP2	Q13535	ATR	S98	S93R	93	Missense	distal	-5	no	10.961	11.143	EPSD	COSMIC	10.658	Up-regulation
Atypical_PIKK_ATR_ATR_ST	Q8IX01	SUGP2	Q13535	ATR	S98	R91K	91	Missense	distal	-7	no	10.961	11.021	EPSD	COSMIC	10.658	Up-regulation
Atypical_PIKK_ATR_ATR_ST	Q8IX01	SUGP2	Q13535	ATR	S133	A139V	139	Missense	distal	6	no	12.685	12.898	EPSD	COSMIC	10.658	Up-regulation
Atypical_PIKK_ATR_ATR_ST	Q8IX01	SUGP2	Q13535	ATR	S133	H130Y	130	Missense	distal	-3	no	12.685	13.353	EPSD	COSMIC	10.658	Up-regulation
Atypical_PIKK_ATR_ATR_ST	Q8IX01	SUGP2	Q13535	ATR	S153	S153Y	153	Missense	central	0	yes	14.834	0.000	EPSD	COSMIC	10.658	Loss
Atypical_PIKK_ATR_ATR_ST	Q8IX01	SUGP2	Q13535	ATR	S153	S157F	157	Missense	distal	4	no	14.834	14.853	EPSD	COSMIC	10.658	Up-regulation
Atypical_PIKK_ATR_ATR_ST	Q8IX01	SUGP2	Q13535	ATR	S159	S163T	163	Missense	distal	4	no	13.745	13.796	EPSD	COSMIC	10.658	Up-regulation
Atypical_PIKK_ATR_ATR_ST	Q8IX01	SUGP2	Q13535	ATR	S159	S153Y	153	Missense	distal	-6	no	13.745	13.918	EPSD	COSMIC	10.658	Up-regulation
Atypical_PIKK_ATR_ATR_ST	Q8IX01	SUGP2	Q13535	ATR	S159	S157F	157	Missense	proximal	-2	no	13.745	14.343	EPSD	COSMIC	10.658	Up-regulation
Atypical_PIKK_ATR_ATR_ST	Q8IX01	SUGP2	Q13535	ATR	S224	S224F	224	Missense	central	0	yes	10.853	0.000	EPSD	COSMIC;GDSC;CCLE	10.658	Loss
Atypical_PIKK_ATR_ATR_ST	Q8IX01	SUGP2	Q13535	ATR	S224	D220N	220	Missense	distal	-4	no	10.853	10.244	EPSD	COSMIC	10.658	Loss
Atypical_PIKK_ATR_ATR_ST	Q8IX01	SUGP2	Q13535	ATR	S251	V258M	258	Missense	distal	7	no	10.692	10.476	EPSD	COSMIC	10.658	Loss
Atypical_PIKK_ATR_ATR_ST	Q8IX01	SUGP2	Q13535	ATR	S251	P256L	256	Missense	distal	5	no	10.692	10.687	EPSD	COSMIC	10.658	Down-regulation
Atypical_PIKK_ATR_ATR_ST	Q8IX01	SUGP2	Q13535	ATR	S251	S251G	251	Missense	central	0	yes	10.692	0.000	EPSD	COSMIC	10.658	Loss
Atypical_PIKK_ATR_ATR_ST	Q8IX01	SUGP2	Q13535	ATR	S251	P256S	256	Missense	distal	5	no	10.692	10.680	EPSD	COSMIC	10.658	Down-regulation
Atypical_PIKK_ATR_ATR_ST	Q8IX01	SUGP2	Q13535	ATR	T265	V258M	258	Missense	distal	-7	no	11.723	11.767	EPSD	COSMIC	10.658	Up-regulation
Atypical_PIKK_ATR_ATR_ST	Q8IX01	SUGP2	Q13535	ATR	T265	T262A	262	Missense	distal	-3	no	11.723	12.284	EPSD	COSMIC;GDSC;CCLE	10.658	Up-regulation
Atypical_PIKK_ATR_ATR_ST	Q8IX01	SUGP2	Q13535	ATR	T265	G267C	267	Missense	proximal	2	no	11.723	9.100	EPSD	COSMIC	10.658	Loss
Atypical_PIKK_ATR_ATR_ST	Q8IX01	SUGP2	Q13535	ATR	T284	G283E	283	Missense	proximal	-1	no	10.718	10.766	EPSD	COSMIC	10.658	Up-regulation
Atypical_PIKK_ATR_ATR_ST	Q8IX01	SUGP2	Q13535	ATR	S641	E642D	642	Missense	proximal	1	no	10.875	11.381	EPSD	COSMIC	10.658	Up-regulation
Atypical_PIKK_ATR_ATR_ST	Q8IX01	SUGP2	Q13535	ATR	S641	R645Q	645	Missense	distal	4	no	10.875	10.709	EPSD	COSMIC	10.658	Down-regulation
Atypical_PIKK_ATR_ATR_ST	Q8IX01	SUGP2	Q13535	ATR	S641	A647V	647	Missense	distal	6	no	10.875	11.088	EPSD	COSMIC	10.658	Up-regulation
Atypical_PIKK_ATR_ATR_ST	Q8IX01	SUGP2	Q13535	ATR	S641	E642K	642	Missense	proximal	1	no	10.875	5.829	EPSD	COSMIC	10.658	Loss
Atypical_PIKK_ATR_ATR_ST	Q8IX01	SUGP2	Q13535	ATR	S664	R665Q	665	Missense	proximal	1	no	9.389	16.384	EPSD	COSMIC	10.658	Gain
Atypical_PIKK_ATR_ATR_ST	Q8IX01	SUGP2	Q13535	ATR	S664	R665L	665	Missense	proximal	1	no	9.389	10.950	EPSD	COSMIC	10.658	Gain
Atypical_PIKK_ATR_ATR_ST	Q8IX01	SUGP2	Q13535	ATR	S721	L727M	727	Missense	distal	6	no	16.167	16.052	EPSD	COSMIC	10.658	Down-regulation
Atypical_PIKK_ATR_ATR_ST	Q8IX01	SUGP2	Q13535	ATR	S721	R715W	715	Missense	distal	-6	no	16.167	16.179	EPSD	COSMIC;GDSC;CCLE	10.658	Up-regulation
Atypical_PIKK_ATR_ATR_ST	Q8IX01	SUGP2	Q13535	ATR	S757	P758S	758	Missense	proximal	1	no	12.725	11.615	EPSD	COSMIC	10.658	Down-regulation
Atypical_PIKK_ATR_ATR_ST	Q8IX01	SUGP2	Q13535	ATR	S757	D764N	764	Missense	distal	7	no	12.725	12.949	EPSD	COSMIC	10.658	Up-regulation
Atypical_PIKK_ATR_ATR_ST	Q8IX01	SUGP2	Q13535	ATR	S860	P864L	864	Missense	distal	4	no	11.580	11.730	EPSD	COSMIC	10.658	Up-regulation
Atypical_PIKK_ATR_ATR_ST	Q8IX01	SUGP2	Q13535	ATR	S860	T858M	858	Missense	proximal	-2	no	11.580	11.647	EPSD	COSMIC	10.658	Up-regulation
Atypical_PIKK_ATR_ATR_ST	Q8IX01	SUGP2	Q13535	ATR	S860	T858A	858	Missense	proximal	-2	no	11.580	12.053	EPSD	COSMIC	10.658	Up-regulation
Atypical_PIKK_ATR_ATR_ST	Q8IX01	SUGP2	Q13535	ATR	S863	P864L	864	Missense	proximal	1	no	10.755	10.189	EPSD	COSMIC	10.658	Loss
Atypical_PIKK_ATR_ATR_ST	Q8IX01	SUGP2	Q13535	ATR	S863	T858M	858	Missense	distal	-5	no	10.755	10.640	EPSD	COSMIC	10.658	Loss
Atypical_PIKK_ATR_ATR_ST	Q8IX01	SUGP2	Q13535	ATR	S863	T858A	858	Missense	distal	-5	no	10.755	10.838	EPSD	COSMIC	10.658	Up-regulation
Atypical_PIKK_ATR_ATR_ST	Q8IX01	SUGP2	Q13535	ATR	S887	E889K	889	Missense	proximal	2	no	13.117	12.168	EPSD	COSMIC	10.658	Down-regulation
Atypical_PIKK_ATR_ATR_ST	Q8IX01	SUGP2	Q13535	ATR	S940	S944L	944	Missense	distal	4	no	14.359	14.596	EPSD	COSMIC	10.658	Up-regulation
Atypical_PIKK_ATR_ATR_ST	Q8IX01	SUGP2	Q13535	ATR	S940	S943P	943	Missense	distal	3	no	14.359	14.295	EPSD	COSMIC	10.658	Down-regulation
Atypical_PIKK_ATR_ATR_ST	Q8IX01	SUGP2	Q13535	ATR	S1047	G1053C	1053	Missense	distal	6	no	11.321	11.379	EPSD	COSMIC	10.658	Up-regulation
Atypical_PIKK_ATR_ATR_ST	Q8IX01	SUGP2	Q13535	ATR	S1047	P1040L	1040	Missense	distal	-7	no	11.321	11.128	EPSD	COSMIC	10.658	Down-regulation
Atypical_PIKK_ATR_ATR_ST	Q8IX01	SUGP2	Q13535	ATR	S1047	G1053D	1053	Missense	distal	6	no	11.321	11.374	EPSD	COSMIC	10.658	Up-regulation
Atypical_PIKK_ATR_ATR_ST	Q9NS23	RASSF1	Q13535	ATR	S135	A137S	137	Missense	proximal	2	no	17.570	17.422	EPSD	COSMIC	10.658	Down-regulation
Atypical_PIKK_ATR_ATR_ST	Q9NS23	RASSF1	Q13535	ATR	S135	I139L	139	Missense	distal	4	no	17.570	17.124	EPSD	COSMIC	10.658	Down-regulation
Atypical_PIKK_ATR_ATR_ST	Q9NS23	RASSF1	Q13535	ATR	S135	I139T	139	Missense	distal	4	no	17.570	16.938	EPSD	COSMIC;GDSC;CCLE	10.658	Down-regulation
Atypical_PIKK_ATR_ATR_ST	Q9NS23	RASSF1	Q13535	ATR	S135	W129C	129	Missense	distal	-6	no	17.570	17.546	EPSD	COSMIC	10.658	Down-regulation
Atypical_PIKK_ATR_ATR_ST	Q9NS23	RASSF1	Q13535	ATR	S188	L189Q	189	Missense	proximal	1	no	8.127	13.560	EPSD	COSMIC	10.658	Gain
Atypical_PIKK_ATR_ATR_ST	Q9H6E5	TUT1	Q13535	ATR	S10	A3V	3	Missense	distal	-7	no	11.244	11.223	EPSD	COSMIC	10.658	Down-regulation
Atypical_PIKK_ATR_ATR_ST	Q9H6E5	TUT1	Q13535	ATR	S238	V232A	232	Missense	distal	-6	no	13.187	13.217	EPSD	COSMIC	10.658	Up-regulation
Atypical_PIKK_ATR_ATR_ST	Q9H6E5	TUT1	Q13535	ATR	S707	D702A	702	Missense	distal	-5	no	12.483	12.411	EPSD	COSMIC	10.658	Down-regulation
Atypical_PIKK_ATR_ATR_ST	Q9H6E5	TUT1	Q13535	ATR	S707	D702H	702	Missense	distal	-5	no	12.483	12.435	EPSD	COSMIC	10.658	Down-regulation
Atypical_PIKK_ATR_ATR_ST	Q9H6E5	TUT1	Q13535	ATR	S707	P708S	708	Missense	proximal	1	no	12.483	11.374	EPSD	COSMIC	10.658	Down-regulation
Atypical_PIKK_ATR_ATR_ST	Q9H6E5	TUT1	Q13535	ATR	S731	H732D	732	Missense	proximal	1	no	0.329	12.433	EPSD	COSMIC	10.658	Gain
Atypical_PIKK_ATR_ATR_ST	Q9H6E5	TUT1	Q13535	ATR	S750	E744Q	744	Missense	distal	-6	no	15.883	15.901	PhosphoSitePlus	COSMIC	10.658	Up-regulation
Atypical_PIKK_ATR_ATR_ST	Q9H6E5	TUT1	Q13535	ATR	S750	A754E	754	Missense	distal	4	no	15.883	15.339	PhosphoSitePlus	COSMIC	10.658	Down-regulation
Atypical_PIKK_ATR_ATR_ST	Q13315	ATM	Q13535	ATR	T86	A88V	88	Missense	proximal	2	no	15.019	15.508	EPSD	COSMIC	10.658	Up-regulation
Atypical_PIKK_ATR_ATR_ST	Q13315	ATM	Q13535	ATR	T86	S83L	83	Missense	distal	-3	no	15.019	15.590	EPSD	COSMIC	10.658	Up-regulation
Atypical_PIKK_ATR_ATR_ST	Q13315	ATM	Q13535	ATR	T86	A84V	84	Missense	proximal	-2	no	15.019	14.499	EPSD	COSMIC	10.658	Down-regulation
Atypical_PIKK_ATR_ATR_ST	Q13315	ATM	Q13535	ATR	S99	M94I	94	Missense	distal	-5	no	11.150	11.455	EPSD	COSMIC	10.658	Up-regulation
Atypical_PIKK_ATR_ATR_ST	Q13315	ATM	Q13535	ATR	S99	Q95K	95	Missense	distal	-4	no	11.150	11.870	EPSD	COSMIC	10.658	Up-regulation
Atypical_PIKK_ATR_ATR_ST	Q13315	ATM	Q13535	ATR	S99	K106T	106	Missense	distal	7	no	11.150	11.210	EPSD	COSMIC	10.658	Up-regulation
Atypical_PIKK_ATR_ATR_ST	Q13315	ATM	Q13535	ATR	S99	M94V	94	Missense	distal	-5	no	11.150	11.351	EPSD	COSMIC	10.658	Up-regulation
Atypical_PIKK_ATR_ATR_ST	Q13315	ATM	Q13535	ATR	S200	D203N	203	Missense	distal	3	no	13.414	13.583	EPSD	COSMIC	10.658	Up-regulation
Atypical_PIKK_ATR_ATR_ST	Q13315	ATM	Q13535	ATR	S200	S207F	207	Missense	distal	7	no	13.414	13.475	EPSD	COSMIC	10.658	Up-regulation
Atypical_PIKK_ATR_ATR_ST	Q13315	ATM	Q13535	ATR	T297	P292R	292	Missense	distal	-5	no	13.489	13.641	EPSD	COSMIC	10.658	Up-regulation
Atypical_PIKK_ATR_ATR_ST	Q13315	ATM	Q13535	ATR	T297	G294E	294	Missense	distal	-3	no	13.489	13.648	EPSD	COSMIC	10.658	Up-regulation
Atypical_PIKK_ATR_ATR_ST	Q13315	ATM	Q13535	ATR	T297	H290L	290	Missense	distal	-7	no	13.489	13.319	EPSD	COSMIC	10.658	Down-regulation
Atypical_PIKK_ATR_ATR_ST	Q13315	ATM	Q13535	ATR	T297	H291R	291	Missense	distal	-6	no	13.489	13.483	EPSD	COSMIC;GDSC;CCLE	10.658	Down-regulation
Atypical_PIKK_ATR_ATR_ST	Q13315	ATM	Q13535	ATR	T297	G301C	301	Missense	distal	4	no	13.489	13.409	EPSD	COSMIC	10.658	Down-regulation
Atypical_PIKK_ATR_ATR_ST	Q13315	ATM	Q13535	ATR	T297	E304G	304	Missense	distal	7	no	13.489	13.493	EPSD	COSMIC	10.658	Up-regulation
Atypical_PIKK_ATR_ATR_ST	Q13315	ATM	Q13535	ATR	S333	G330V	330	Missense	distal	-3	no	11.120	11.520	EPSD	COSMIC	10.658	Up-regulation
Atypical_PIKK_ATR_ATR_ST	Q13315	ATM	Q13535	ATR	S333	K331N	331	Missense	proximal	-2	no	11.120	11.574	EPSD	COSMIC	10.658	Up-regulation
Atypical_PIKK_ATR_ATR_ST	Q13315	ATM	Q13535	ATR	S333	Y332C	332	Missense	proximal	-1	no	11.120	11.340	EPSD	COSMIC	10.658	Up-regulation
Atypical_PIKK_ATR_ATR_ST	Q13315	ATM	Q13535	ATR	S333	R337S	337	Missense	distal	4	no	11.120	11.068	EPSD	COSMIC	10.658	Down-regulation
Atypical_PIKK_ATR_ATR_ST	Q13315	ATM	Q13535	ATR	S333	S334L	334	Missense	proximal	1	no	11.120	11.664	EPSD	COSMIC	10.658	Up-regulation
Atypical_PIKK_ATR_ATR_ST	Q13315	ATM	Q13535	ATR	S333	R337P	337	Missense	distal	4	no	11.120	11.155	EPSD	COSMIC	10.658	Up-regulation
Atypical_PIKK_ATR_ATR_ST	Q13315	ATM	Q13535	ATR	S367	T372A	372	Missense	distal	5	no	10.982	10.985	EPSD	COSMIC	10.658	Up-regulation
Atypical_PIKK_ATR_ATR_ST	Q13315	ATM	Q13535	ATR	T373	Y380N	380	Missense	distal	7	no	14.349	14.545	EPSD	COSMIC	10.658	Up-regulation
Atypical_PIKK_ATR_ATR_ST	Q13315	ATM	Q13535	ATR	T373	T372A	372	Missense	proximal	-1	no	14.349	14.579	EPSD	COSMIC	10.658	Up-regulation
Atypical_PIKK_ATR_ATR_ST	Q13315	ATM	Q13535	ATR	S440	P434L	434	Missense	distal	-6	no	13.847	13.911	EPSD	COSMIC	10.658	Up-regulation
Atypical_PIKK_ATR_ATR_ST	Q13315	ATM	Q13535	ATR	S646	E647Q	647	Missense	proximal	1	no	11.541	17.462	EPSD	COSMIC	10.658	Up-regulation
Atypical_PIKK_ATR_ATR_ST	Q13315	ATM	Q13535	ATR	S646	E641K	641	Missense	distal	-5	no	11.541	11.622	EPSD	COSMIC	10.658	Up-regulation
Atypical_PIKK_ATR_ATR_ST	Q13315	ATM	Q13535	ATR	S646	E649Q	649	Missense	distal	3	no	11.541	11.425	EPSD	COSMIC	10.658	Down-regulation
Atypical_PIKK_ATR_ATR_ST	Q13315	ATM	Q13535	ATR	S646	L653I	653	Missense	distal	7	no	11.541	11.700	EPSD	COSMIC	10.658	Up-regulation
Atypical_PIKK_ATR_ATR_ST	Q13315	ATM	Q13535	ATR	S646	S646L	646	Missense	central	0	yes	11.541	0.000	EPSD	COSMIC	10.658	Loss
Atypical_PIKK_ATR_ATR_ST	Q13315	ATM	Q13535	ATR	S1878	F1877L	1877	Missense	proximal	-1	no	13.195	13.429	EPSD	COSMIC	10.658	Up-regulation
Atypical_PIKK_ATR_ATR_ST	Q13315	ATM	Q13535	ATR	S1878	F1877Y	1877	Missense	proximal	-1	no	13.195	13.524	EPSD	COSMIC	10.658	Up-regulation
Atypical_PIKK_ATR_ATR_ST	Q13315	ATM	Q13535	ATR	S1878	T1880R	1880	Missense	proximal	2	no	13.195	13.312	EPSD	COSMIC	10.658	Up-regulation
Atypical_PIKK_ATR_ATR_ST	Q13315	ATM	Q13535	ATR	S1878	C1873Y	1873	Missense	distal	-5	no	13.195	13.333	EPSD	COSMIC	10.658	Up-regulation
Atypical_PIKK_ATR_ATR_ST	Q13315	ATM	Q13535	ATR	S1981	I1986M	1986	Missense	distal	5	no	15.195	15.191	PhosphoSitePlus	COSMIC	10.658	Down-regulation
Atypical_PIKK_ATR_ATR_ST	Q13315	ATM	Q13535	ATR	S1981	A1976S	1976	Missense	distal	-5	no	15.195	15.099	PhosphoSitePlus	COSMIC	10.658	Down-regulation
Atypical_PIKK_ATR_ATR_ST	Q13315	ATM	Q13535	ATR	S1981	Q1982K	1982	Missense	proximal	1	no	15.195	4.228	PhosphoSitePlus	COSMIC	10.658	Loss
Atypical_PIKK_ATR_ATR_ST	Q13315	ATM	Q13535	ATR	S1981	G1980R	1980	Missense	proximal	-1	no	15.195	15.228	PhosphoSitePlus	COSMIC	10.658	Up-regulation
Atypical_PIKK_ATR_ATR_ST	Q13315	ATM	Q13535	ATR	S1981	E1978V	1978	Missense	distal	-3	no	15.195	15.435	PhosphoSitePlus	COSMIC	10.658	Up-regulation
Atypical_PIKK_ATR_ATR_ST	Q13315	ATM	Q13535	ATR	S1981	S1983C	1983	Missense	proximal	2	no	15.195	13.511	PhosphoSitePlus	COSMIC	10.658	Down-regulation
Atypical_PIKK_ATR_ATR_ST	Q13315	ATM	Q13535	ATR	S2162	S2165F	2165	Missense	distal	3	no	12.542	11.511	EPSD	COSMIC;GDSC;CCLE	10.658	Down-regulation
Atypical_PIKK_ATR_ATR_ST	Q13315	ATM	Q13535	ATR	S2162	E2157Q	2157	Missense	distal	-5	no	12.542	12.715	EPSD	COSMIC	10.658	Up-regulation
Atypical_PIKK_ATR_ATR_ST	Q13315	ATM	Q13535	ATR	S2162	V2166A	2166	Missense	distal	4	no	12.542	12.681	EPSD	COSMIC;GDSC;CCLE	10.658	Up-regulation
Atypical_PIKK_ATR_ATR_ST	Q13315	ATM	Q13535	ATR	S2162	R2161H	2161	Missense	proximal	-1	no	12.542	12.436	EPSD	COSMIC;CCLE	10.658	Down-regulation
Atypical_PIKK_ATR_ATR_ST	Q13315	ATM	Q13535	ATR	S2242	E2238V	2238	Missense	distal	-4	no	14.196	12.713	EPSD	COSMIC	10.658	Down-regulation
Atypical_PIKK_ATR_ATR_ST	Q13315	ATM	Q13535	ATR	S2242	D2240A	2240	Missense	proximal	-2	no	14.196	14.579	EPSD	COSMIC	10.658	Up-regulation
Atypical_PIKK_ATR_ATR_ST	Q13315	ATM	Q13535	ATR	S2242	E2245K	2245	Missense	distal	3	no	14.196	14.352	EPSD	COSMIC	10.658	Up-regulation
Atypical_PIKK_ATR_ATR_ST	Q13315	ATM	Q13535	ATR	S2242	E2238K	2238	Missense	distal	-4	no	14.196	13.785	EPSD	COSMIC	10.658	Down-regulation
Atypical_PIKK_ATR_ATR_ST	Q13315	ATM	Q13535	ATR	S2592	L2594F	2594	Missense	proximal	2	no	13.565	11.843	EPSD	COSMIC	10.658	Down-regulation
Atypical_PIKK_ATR_ATR_ST	Q13315	ATM	Q13535	ATR	S2592	D2597H	2597	Missense	distal	5	no	13.565	13.561	EPSD	COSMIC	10.658	Down-regulation
Atypical_PIKK_ATR_ATR_ST	Q13315	ATM	Q13535	ATR	S2592	Q2593R	2593	Missense	proximal	1	no	13.565	6.570	EPSD	COSMIC	10.658	Loss
Atypical_PIKK_ATR_ATR_ST	P16220	CREB1	Q13535	ATR	T100	S103N	103	Missense	distal	3	no	11.730	11.475	EPSD	COSMIC	10.658	Down-regulation
Atypical_PIKK_ATR_ATR_ST	P16220	CREB1	Q13535	ATR	T100	R95I	95	Missense	distal	-5	no	11.730	11.751	EPSD	COSMIC	10.658	Up-regulation
Atypical_PIKK_ATR_ATR_ST	P16220	CREB1	Q13535	ATR	T100	I102M	102	Missense	proximal	2	no	11.730	12.809	EPSD	COSMIC	10.658	Up-regulation
Atypical_PIKK_ATR_ATR_ST	P16220	CREB1	Q13535	ATR	S111	S117N	117	Missense	distal	6	no	13.253	13.367	EPSD	COSMIC	10.658	Up-regulation
Atypical_PIKK_ATR_ATR_ST	P16220	CREB1	Q13535	ATR	S111	V118L	118	Missense	distal	7	no	13.253	13.204	EPSD	COSMIC	10.658	Down-regulation
Atypical_PIKK_ATR_ATR_ST	P16220	CREB1	Q13535	ATR	S111	E109K	109	Missense	proximal	-2	no	13.253	13.352	EPSD	COSMIC	10.658	Up-regulation
Atypical_PIKK_ATR_ATR_ST	P16220	CREB1	Q13535	ATR	S111	V118I	118	Missense	distal	7	no	13.253	13.362	EPSD	COSMIC	10.658	Up-regulation
Atypical_PIKK_ATR_ATR_ST	P16220	CREB1	Q13535	ATR	S121	S117N	117	Missense	distal	-4	no	16.403	16.626	PhosphoSitePlus	COSMIC	10.658	Up-regulation
Atypical_PIKK_ATR_ATR_ST	P16220	CREB1	Q13535	ATR	S121	R124Q	124	Missense	distal	3	no	16.403	16.408	PhosphoSitePlus	COSMIC	10.658	Up-regulation
Atypical_PIKK_ATR_ATR_ST	P16220	CREB1	Q13535	ATR	S121	V118L	118	Missense	distal	-3	no	16.403	16.534	PhosphoSitePlus	COSMIC	10.658	Up-regulation
Atypical_PIKK_ATR_ATR_ST	P16220	CREB1	Q13535	ATR	S121	R125T	125	Missense	distal	4	no	16.403	16.402	PhosphoSitePlus	COSMIC	10.658	Down-regulation
Atypical_PIKK_ATR_ATR_ST	P16220	CREB1	Q13535	ATR	S121	L128R	128	Missense	distal	7	no	16.403	16.465	PhosphoSitePlus	COSMIC	10.658	Up-regulation
Atypical_PIKK_ATR_ATR_ST	P16220	CREB1	Q13535	ATR	S121	V118I	118	Missense	distal	-3	no	16.403	15.986	PhosphoSitePlus	COSMIC	10.658	Down-regulation
Atypical_PIKK_ATR_ATR_ST	P16220	CREB1	Q13535	ATR	T276	A269T	269	Missense	distal	-7	no	11.054	11.031	EPSD	COSMIC	10.658	Down-regulation
Atypical_PIKK_ATR_ATR_ST	O96017	CHEK2	Q13535	ATR	S12	H13N	13	Missense	proximal	1	no	-1.000	12.242	EPSD	COSMIC	10.658	Gain
Atypical_PIKK_ATR_ATR_ST	O96017	CHEK2	Q13535	ATR	S19	H13Y	13	Missense	distal	-6	no	15.174	15.259	EPSD	COSMIC	10.658	Up-regulation
Atypical_PIKK_ATR_ATR_ST	O96017	CHEK2	Q13535	ATR	S19	V25I	25	Missense	distal	6	no	15.174	15.014	EPSD	COSMIC	10.658	Down-regulation
Atypical_PIKK_ATR_ATR_ST	O96017	CHEK2	Q13535	ATR	S19	H13N	13	Missense	distal	-6	no	15.174	15.152	EPSD	COSMIC	10.658	Down-regulation
Atypical_PIKK_ATR_ATR_ST	O96017	CHEK2	Q13535	ATR	S19	S19L	19	Missense	central	0	yes	15.174	0.000	EPSD	COSMIC	10.658	Loss
Atypical_PIKK_ATR_ATR_ST	O96017	CHEK2	Q13535	ATR	S28	V25I	25	Missense	distal	-3	no	13.836	13.420	EPSD	COSMIC	10.658	Down-regulation
Atypical_PIKK_ATR_ATR_ST	O96017	CHEK2	Q13535	ATR	S50	M46T	46	Missense	distal	-4	no	15.918	16.050	EPSD	COSMIC	10.658	Up-regulation
Atypical_PIKK_ATR_ATR_ST	O96017	CHEK2	Q13535	ATR	S50	S52P	52	Missense	proximal	2	no	15.918	16.233	EPSD	COSMIC;GDSC;CCLE	10.658	Up-regulation
Atypical_PIKK_ATR_ATR_ST	O96017	CHEK2	Q13535	ATR	S50	S49C	49	Missense	proximal	-1	no	15.918	16.469	EPSD	COSMIC	10.658	Up-regulation
Atypical_PIKK_ATR_ATR_ST	O96017	CHEK2	Q13535	ATR	S50	S50N	50	Missense	central	0	yes	15.918	0.000	EPSD	COSMIC	10.658	Loss
Atypical_PIKK_ATR_ATR_ST	O96017	CHEK2	Q13535	ATR	T68	Q69R	69	Missense	proximal	1	no	14.803	7.808	PhosphoSitePlus	COSMIC	10.658	Loss
Atypical_PIKK_ATR_ATR_ST	O96017	CHEK2	Q13535	ATR	S357	D361Y	361	Missense	distal	4	no	12.798	13.305	EPSD	COSMIC	10.658	Up-regulation
Atypical_PIKK_ATR_ATR_ST	O96017	CHEK2	Q13535	ATR	S357	E360Q	360	Missense	distal	3	no	12.798	12.682	EPSD	COSMIC	10.658	Down-regulation
Atypical_PIKK_ATR_ATR_ST	O96017	CHEK2	Q13535	ATR	S357	D361E	361	Missense	distal	4	no	12.798	12.609	EPSD	COSMIC	10.658	Down-regulation
Atypical_PIKK_ATR_ATR_ST	O96017	CHEK2	Q13535	ATR	S357	S356L	356	Missense	proximal	-1	no	12.798	13.034	EPSD	COSMIC	10.658	Up-regulation
Atypical_PIKK_ATR_ATR_ST	O96017	CHEK2	Q13535	ATR	S357	L355P	355	Missense	proximal	-2	no	12.798	12.147	EPSD	COSMIC;CCLE	10.658	Down-regulation
Atypical_PIKK_ATR_ATR_ST	O96017	CHEK2	Q13535	ATR	T432	P426L	426	Missense	distal	-6	no	11.577	11.641	EPSD	COSMIC	10.658	Up-regulation
Atypical_PIKK_ATR_ATR_ST	O96017	CHEK2	Q13535	ATR	T432	K437Q	437	Missense	distal	5	no	11.577	11.575	EPSD	COSMIC	10.658	Down-regulation
Atypical_PIKK_ATR_ATR_ST	O96017	CHEK2	Q13535	ATR	S500	K494M	494	Missense	distal	-6	no	11.225	11.281	EPSD	COSMIC	10.658	Up-regulation
Atypical_PIKK_ATR_ATR_ST	O96017	CHEK2	Q13535	ATR	S518	R519Q	519	Missense	proximal	1	no	7.577	14.573	EPSD	COSMIC	10.658	Gain
Atypical_PIKK_ATR_ATR_ST	Q13535	ATR	Q13535	ATR	S61	V66E	66	Missense	distal	5	no	13.209	13.201	EPSD	COSMIC	10.658	Down-regulation
Atypical_PIKK_ATR_ATR_ST	Q13535	ATR	Q13535	ATR	S61	L55I	55	Missense	distal	-6	no	13.209	13.183	EPSD	COSMIC	10.658	Down-regulation
Atypical_PIKK_ATR_ATR_ST	Q13535	ATR	Q13535	ATR	S61	S65F	65	Missense	distal	4	no	13.209	13.228	EPSD	COSMIC	10.658	Up-regulation
Atypical_PIKK_ATR_ATR_ST	Q13535	ATR	Q13535	ATR	S61	D60G	60	Missense	proximal	-1	no	13.209	13.115	EPSD	COSMIC	10.658	Down-regulation
Atypical_PIKK_ATR_ATR_ST	Q13535	ATR	Q13535	ATR	S61	S61F	61	Missense	central	0	yes	13.209	0.000	EPSD	COSMIC	10.658	Loss
Atypical_PIKK_ATR_ATR_ST	Q13535	ATR	Q13535	ATR	T415	E410D	410	Missense	distal	-5	no	10.424	10.677	EPSD	COSMIC	10.658	Gain
Atypical_PIKK_ATR_ATR_ST	Q13535	ATR	Q13535	ATR	S428	R433S	433	Missense	distal	5	no	12.064	12.053	EPSD	COSMIC	10.658	Down-regulation
Atypical_PIKK_ATR_ATR_ST	Q13535	ATR	Q13535	ATR	S436	L438V	438	Missense	proximal	2	no	9.813	11.415	EPSD	COSMIC	10.658	Gain
Atypical_PIKK_ATR_ATR_ST	Q13535	ATR	Q13535	ATR	S634	R635Q	635	Missense	proximal	1	no	7.089	14.084	EPSD	COSMIC	10.658	Gain
Atypical_PIKK_ATR_ATR_ST	Q13535	ATR	Q13535	ATR	S776	L780I	780	Missense	distal	4	no	10.772	11.217	EPSD	COSMIC	10.658	Up-regulation
Atypical_PIKK_ATR_ATR_ST	Q13535	ATR	Q13535	ATR	S776	L769I	769	Missense	distal	-7	no	10.772	10.820	EPSD	COSMIC	10.658	Up-regulation
Atypical_PIKK_ATR_ATR_ST	Q13535	ATR	Q13535	ATR	S1154	A1151V	1151	Missense	distal	-3	no	12.269	11.869	EPSD	COSMIC	10.658	Down-regulation
Atypical_PIKK_ATR_ATR_ST	Q13535	ATR	Q13535	ATR	S1154	M1159I	1159	Missense	distal	5	no	12.269	12.272	EPSD	COSMIC	10.658	Up-regulation
Atypical_PIKK_ATR_ATR_ST	Q13535	ATR	Q13535	ATR	S1154	K1160E	1160	Missense	distal	6	no	12.269	12.468	EPSD	COSMIC	10.658	Up-regulation
Atypical_PIKK_ATR_ATR_ST	Q13535	ATR	Q13535	ATR	S1333	Q1334E	1334	Missense	proximal	1	no	14.151	8.231	EPSD	COSMIC	10.658	Loss
Atypical_PIKK_ATR_ATR_ST	Q13535	ATR	Q13535	ATR	S1333	V1338L	1338	Missense	distal	5	no	14.151	14.156	EPSD	COSMIC;GDSC;CCLE	10.658	Up-regulation
Atypical_PIKK_ATR_ATR_ST	Q13535	ATR	Q13535	ATR	S1333	Q1334H	1334	Missense	proximal	1	no	14.151	-3.367	EPSD	COSMIC	10.658	Loss
Atypical_PIKK_ATR_ATR_ST	Q13535	ATR	Q13535	ATR	S1333	L1340F	1340	Missense	distal	7	no	14.151	14.052	EPSD	COSMIC	10.658	Down-regulation
Atypical_PIKK_ATR_ATR_ST	Q13535	ATR	Q13535	ATR	T1566	T1563A	1563	Missense	distal	-3	no	12.550	13.112	EPSD	COSMIC	10.658	Up-regulation
Atypical_PIKK_ATR_ATR_ST	Q13535	ATR	Q13535	ATR	T1566	S1571F	1571	Missense	distal	5	no	12.550	12.562	EPSD	COSMIC	10.658	Up-regulation
Atypical_PIKK_ATR_ATR_ST	Q13535	ATR	Q13535	ATR	T1566	D1560Y	1560	Missense	distal	-6	no	12.550	12.660	EPSD	COSMIC	10.658	Up-regulation
Atypical_PIKK_ATR_ATR_ST	Q13535	ATR	Q13535	ATR	T1566	D1568E	1568	Missense	proximal	2	no	12.550	14.226	EPSD	COSMIC	10.658	Up-regulation
Atypical_PIKK_ATR_ATR_ST	Q13535	ATR	Q13535	ATR	T1566	T1566N	1566	Missense	central	0	yes	12.550	0.000	EPSD	COSMIC	10.658	Loss
Atypical_PIKK_ATR_ATR_ST	Q13535	ATR	Q13535	ATR	T1578	V1581L	1581	Missense	distal	3	no	12.280	11.513	EPSD	COSMIC	10.658	Down-regulation
Atypical_PIKK_ATR_ATR_ST	Q13535	ATR	Q13535	ATR	T1578	S1571F	1571	Missense	distal	-7	no	12.280	12.172	EPSD	COSMIC	10.658	Down-regulation
Atypical_PIKK_ATR_ATR_ST	Q13535	ATR	Q13535	ATR	T1589	K1595I	1595	Missense	distal	6	no	14.249	14.091	EPSD	COSMIC	10.658	Down-regulation
Atypical_PIKK_ATR_ATR_ST	Q13535	ATR	Q13535	ATR	T1652	R1653Q	1653	Missense	proximal	1	no	5.434	12.430	EPSD	COSMIC	10.658	Gain
Atypical_PIKK_ATR_ATR_ST	Q13535	ATR	Q13535	ATR	S1876	S1875R	1875	Missense	proximal	-1	no	11.526	11.654	EPSD	COSMIC	10.658	Up-regulation
Atypical_PIKK_ATR_ATR_ST	Q13535	ATR	Q13535	ATR	S1876	P1872T	1872	Missense	distal	-4	no	11.526	11.115	EPSD	COSMIC	10.658	Down-regulation
Atypical_PIKK_ATR_ATR_ST	Q13535	ATR	Q13535	ATR	S1876	Q1877E	1877	Missense	proximal	1	no	11.526	5.606	EPSD	COSMIC	10.658	Loss
Atypical_PIKK_ATR_ATR_ST	Q13535	ATR	Q13535	ATR	S1876	Q1869R	1869	Missense	distal	-7	no	11.526	11.495	EPSD	COSMIC	10.658	Down-regulation
Atypical_PIKK_ATR_ATR_ST	Q13535	ATR	Q13535	ATR	S1876	S1875N	1875	Missense	proximal	-1	no	11.526	12.004	EPSD	COSMIC	10.658	Up-regulation
Atypical_PIKK_ATR_ATR_ST	Q13535	ATR	Q13535	ATR	S1876	S1880F	1880	Missense	distal	4	no	11.526	11.545	EPSD	COSMIC	10.658	Up-regulation
Atypical_PIKK_ATR_ATR_ST	Q13535	ATR	Q13535	ATR	T1890	E1888K	1888	Missense	proximal	-2	no	13.617	13.717	EPSD	COSMIC	10.658	Up-regulation
Atypical_PIKK_ATR_ATR_ST	Q13535	ATR	Q13535	ATR	T1890	R1895T	1895	Missense	distal	5	no	13.617	13.615	EPSD	COSMIC;CCLE	10.658	Down-regulation
Atypical_PIKK_ATR_ATR_ST	Q13535	ATR	Q13535	ATR	T1890	R1886Q	1886	Missense	distal	-4	no	13.617	13.799	EPSD	COSMIC	10.658	Up-regulation
Atypical_PIKK_ATR_ATR_ST	Q13535	ATR	Q13535	ATR	T1989	M1996T	1996	Missense	distal	7	no	11.074	11.251	PhosphoSitePlus	COSMIC;GDSC	10.658	Up-regulation
Atypical_PIKK_ATR_ATR_ST	Q13535	ATR	Q13535	ATR	T1989	P1991S	1991	Missense	proximal	2	no	11.074	10.758	PhosphoSitePlus	COSMIC;GDSC;CCLE	10.658	Down-regulation
Atypical_PIKK_ATR_ATR_ST	Q13535	ATR	Q13535	ATR	T1989	E1988K	1988	Missense	proximal	-1	no	11.074	10.825	PhosphoSitePlus	COSMIC	10.658	Down-regulation
Atypical_PIKK_ATR_ATR_ST	Q13535	ATR	Q13535	ATR	T1989	T1989P	1989	Missense	central	0	yes	11.074	0.000	PhosphoSitePlus	COSMIC	10.658	Loss
Atypical_PIKK_ATR_ATR_ST	Q13535	ATR	Q13535	ATR	T1989	P1985L	1985	Missense	distal	-4	no	11.074	9.874	PhosphoSitePlus	COSMIC	10.658	Loss
Atypical_PIKK_ATR_ATR_ST	Q13535	ATR	Q13535	ATR	T1989	L1982I	1982	Missense	distal	-7	no	11.074	11.122	PhosphoSitePlus	COSMIC	10.658	Up-regulation
Atypical_PIKK_ATR_ATR_ST	Q13535	ATR	Q13535	ATR	T1989	E1986K	1986	Missense	distal	-3	no	11.074	10.798	PhosphoSitePlus	COSMIC	10.658	Down-regulation
Atypical_PIKK_ATR_ATR_ST	P35568	IRS1	Q13535	ATR	S11	S11L	11	Missense	central	0	yes	11.427	0.000	EPSD	COSMIC	10.658	Loss
Atypical_PIKK_ATR_ATR_ST	P35568	IRS1	Q13535	ATR	S11	G9D	9	Missense	proximal	-2	no	11.427	11.506	EPSD	COSMIC	10.658	Up-regulation
Atypical_PIKK_ATR_ATR_ST	P35568	IRS1	Q13535	ATR	S11	G17C	17	Missense	distal	6	no	11.427	11.486	EPSD	COSMIC	10.658	Up-regulation
Atypical_PIKK_ATR_ATR_ST	P35568	IRS1	Q13535	ATR	S24	K27R	27	Missense	distal	3	no	11.040	10.762	EPSD	COSMIC	10.658	Down-regulation
Atypical_PIKK_ATR_ATR_ST	P35568	IRS1	Q13535	ATR	S24	V31I	31	Missense	distal	7	no	11.040	11.149	EPSD	COSMIC	10.658	Up-regulation
Atypical_PIKK_ATR_ATR_ST	P35568	IRS1	Q13535	ATR	S24	G17C	17	Missense	distal	-7	no	11.040	10.863	EPSD	COSMIC	10.658	Down-regulation
Atypical_PIKK_ATR_ATR_ST	P35568	IRS1	Q13535	ATR	S99	E100K	100	Missense	proximal	1	no	10.841	5.796	EPSD	COSMIC	10.658	Loss
Atypical_PIKK_ATR_ATR_ST	P35568	IRS1	Q13535	ATR	S99	E100Q	100	Missense	proximal	1	no	10.841	16.762	EPSD	COSMIC	10.658	Up-regulation
Atypical_PIKK_ATR_ATR_ST	P35568	IRS1	Q13535	ATR	S270	R265C	265	Missense	distal	-5	no	14.440	14.447	PhosphoSitePlus	COSMIC	10.658	Up-regulation
Atypical_PIKK_ATR_ATR_ST	P35568	IRS1	Q13535	ATR	S270	S274P	274	Missense	distal	4	no	14.440	14.526	PhosphoSitePlus	COSMIC	10.658	Up-regulation
Atypical_PIKK_ATR_ATR_ST	P35568	IRS1	Q13535	ATR	S277	V282I	282	Missense	distal	5	no	14.052	14.063	EPSD	COSMIC	10.658	Up-regulation
Atypical_PIKK_ATR_ATR_ST	P35568	IRS1	Q13535	ATR	S277	S274P	274	Missense	distal	-3	no	14.052	14.329	EPSD	COSMIC	10.658	Up-regulation
Atypical_PIKK_ATR_ATR_ST	P35568	IRS1	Q13535	ATR	S295	R301C	301	Missense	distal	6	no	15.361	15.574	EPSD	COSMIC	10.658	Up-regulation
Atypical_PIKK_ATR_ATR_ST	P35568	IRS1	Q13535	ATR	S295	Q296R	296	Missense	proximal	1	no	15.361	8.366	EPSD	COSMIC;GDSC	10.658	Loss
Atypical_PIKK_ATR_ATR_ST	P35568	IRS1	Q13535	ATR	S295	R302L	302	Missense	distal	7	no	15.361	15.299	EPSD	COSMIC	10.658	Down-regulation
Atypical_PIKK_ATR_ATR_ST	P35568	IRS1	Q13535	ATR	S295	L289F	289	Missense	distal	-6	no	15.361	15.331	EPSD	COSMIC	10.658	Down-regulation
Atypical_PIKK_ATR_ATR_ST	P35568	IRS1	Q13535	ATR	S295	P292S	292	Missense	distal	-3	no	15.361	15.085	EPSD	COSMIC	10.658	Down-regulation
Atypical_PIKK_ATR_ATR_ST	P35568	IRS1	Q13535	ATR	S295	P294T	294	Missense	proximal	-1	no	15.361	15.193	EPSD	COSMIC	10.658	Down-regulation
Atypical_PIKK_ATR_ATR_ST	P35568	IRS1	Q13535	ATR	S315	A310T	310	Missense	distal	-5	no	10.769	10.686	EPSD	COSMIC	10.658	Down-regulation
Atypical_PIKK_ATR_ATR_ST	P35568	IRS1	Q13535	ATR	S315	P313L	313	Missense	proximal	-2	no	10.769	11.420	EPSD	COSMIC;GDSC;CCLE	10.658	Up-regulation
Atypical_PIKK_ATR_ATR_ST	P35568	IRS1	Q13535	ATR	S315	M316V	316	Missense	proximal	1	no	10.769	-4.840	EPSD	COSMIC	10.658	Loss
Atypical_PIKK_ATR_ATR_ST	P35568	IRS1	Q13535	ATR	S315	M316I	316	Missense	proximal	1	no	10.769	7.365	EPSD	COSMIC	10.658	Loss
Atypical_PIKK_ATR_ATR_ST	P35568	IRS1	Q13535	ATR	S315	I308M	308	Missense	distal	-7	no	10.769	10.874	EPSD	COSMIC	10.658	Up-regulation
Atypical_PIKK_ATR_ATR_ST	P35568	IRS1	Q13535	ATR	S315	A310V	310	Missense	distal	-5	no	10.769	10.772	EPSD	COSMIC	10.658	Up-regulation
Atypical_PIKK_ATR_ATR_ST	P35568	IRS1	Q13535	ATR	S330	E333K	333	Missense	distal	3	no	10.610	10.767	EPSD	COSMIC	10.658	Gain
Atypical_PIKK_ATR_ATR_ST	P35568	IRS1	Q13535	ATR	S345	S341L	341	Missense	distal	-4	no	11.532	10.658	EPSD	COSMIC	10.658	Down-regulation
Atypical_PIKK_ATR_ATR_ST	P35568	IRS1	Q13535	ATR	S345	N352D	352	Missense	distal	7	no	11.532	11.308	EPSD	COSMIC	10.658	Down-regulation
Atypical_PIKK_ATR_ATR_ST	P35568	IRS1	Q13535	ATR	S345	P349L	349	Missense	distal	4	no	11.532	11.683	EPSD	COSMIC	10.658	Up-regulation
Atypical_PIKK_ATR_ATR_ST	P35568	IRS1	Q13535	ATR	S345	P346S	346	Missense	proximal	1	no	11.532	10.423	EPSD	COSMIC	10.658	Loss
Atypical_PIKK_ATR_ATR_ST	P35568	IRS1	Q13535	ATR	T397	S398G	398	Missense	proximal	1	no	10.745	7.777	EPSD	COSMIC	10.658	Loss
Atypical_PIKK_ATR_ATR_ST	P35568	IRS1	Q13535	ATR	T397	G401D	401	Missense	distal	4	no	10.745	9.923	EPSD	COSMIC	10.658	Loss
Atypical_PIKK_ATR_ATR_ST	P35568	IRS1	Q13535	ATR	T397	T403S	403	Missense	distal	6	no	10.745	10.791	EPSD	COSMIC	10.658	Up-regulation
Atypical_PIKK_ATR_ATR_ST	P35568	IRS1	Q13535	ATR	T397	H400Q	400	Missense	distal	3	no	10.745	10.342	EPSD	COSMIC	10.658	Loss
Atypical_PIKK_ATR_ATR_ST	P35568	IRS1	Q13535	ATR	T397	S395I	395	Missense	proximal	-2	no	10.745	11.242	EPSD	COSMIC;GDSC;CCLE	10.658	Up-regulation
Atypical_PIKK_ATR_ATR_ST	P35568	IRS1	Q13535	ATR	T446	D448E	448	Missense	proximal	2	no	9.621	11.297	EPSD	COSMIC	10.658	Gain
Atypical_PIKK_ATR_ATR_ST	P35568	IRS1	Q13535	ATR	S449	G451C	451	Missense	proximal	2	no	13.391	10.769	EPSD	COSMIC	10.658	Down-regulation
Atypical_PIKK_ATR_ATR_ST	P35568	IRS1	Q13535	ATR	S449	D448E	448	Missense	proximal	-1	no	13.391	13.346	EPSD	COSMIC	10.658	Down-regulation
Atypical_PIKK_ATR_ATR_ST	P35568	IRS1	Q13535	ATR	S449	T453I	453	Missense	distal	4	no	13.391	14.023	EPSD	COSMIC	10.658	Up-regulation
Atypical_PIKK_ATR_ATR_ST	P35568	IRS1	Q13535	ATR	S449	R443C	443	Missense	distal	-6	no	13.391	13.378	EPSD	COSMIC	10.658	Down-regulation
Atypical_PIKK_ATR_ATR_ST	P35568	IRS1	Q13535	ATR	S449	P447L	447	Missense	proximal	-2	no	13.391	14.042	EPSD	COSMIC	10.658	Up-regulation
Atypical_PIKK_ATR_ATR_ST	P35568	IRS1	Q13535	ATR	S449	R443L	443	Missense	distal	-6	no	13.391	13.418	EPSD	COSMIC	10.658	Up-regulation
Atypical_PIKK_ATR_ATR_ST	P35568	IRS1	Q13535	ATR	S449	S444I	444	Missense	distal	-5	no	13.391	13.594	EPSD	COSMIC	10.658	Up-regulation
Atypical_PIKK_ATR_ATR_ST	P35568	IRS1	Q13535	ATR	S449	S449P	449	Missense	central	0	yes	13.391	0.000	EPSD	COSMIC	10.658	Loss
Atypical_PIKK_ATR_ATR_ST	P35568	IRS1	Q13535	ATR	S463	E460K	460	Missense	distal	-3	no	13.218	12.943	EPSD	COSMIC	10.658	Down-regulation
Atypical_PIKK_ATR_ATR_ST	P35568	IRS1	Q13535	ATR	S463	G458A	458	Missense	distal	-5	no	13.218	13.298	EPSD	COSMIC	10.658	Up-regulation
Atypical_PIKK_ATR_ATR_ST	P35568	IRS1	Q13535	ATR	S463	M468I	468	Missense	distal	5	no	13.218	13.222	EPSD	COSMIC;GDSC;CCLE	10.658	Up-regulation
Atypical_PIKK_ATR_ATR_ST	P35568	IRS1	Q13535	ATR	S463	G470V	470	Missense	distal	7	no	13.218	13.462	EPSD	COSMIC;GDSC;CCLE	10.658	Up-regulation
Atypical_PIKK_ATR_ATR_ST	P35568	IRS1	Q13535	ATR	S547	M554T	554	Missense	distal	7	no	11.112	11.289	EPSD	COSMIC	10.658	Up-regulation
Atypical_PIKK_ATR_ATR_ST	P35568	IRS1	Q13535	ATR	S547	Y551C	551	Missense	distal	4	no	11.112	11.347	EPSD	COSMIC	10.658	Up-regulation
Atypical_PIKK_ATR_ATR_ST	P35568	IRS1	Q13535	ATR	S694	G696A	696	Missense	proximal	2	no	10.973	10.182	EPSD	COSMIC;GDSC;CCLE	10.658	Loss
Atypical_PIKK_ATR_ATR_ST	P35568	IRS1	Q13535	ATR	S694	A688T	688	Missense	distal	-6	no	10.973	10.951	EPSD	COSMIC	10.658	Down-regulation
Atypical_PIKK_ATR_ATR_ST	P35568	IRS1	Q13535	ATR	S694	Y695F	695	Missense	proximal	1	no	10.973	10.602	EPSD	COSMIC;GDSC	10.658	Loss
Atypical_PIKK_ATR_ATR_ST	P35568	IRS1	Q13535	ATR	S741	V738G	738	Missense	distal	-3	no	10.880	10.480	EPSD	COSMIC	10.658	Loss
Atypical_PIKK_ATR_ATR_ST	P35568	IRS1	Q13535	ATR	S741	G739E	739	Missense	proximal	-2	no	10.880	10.863	EPSD	COSMIC	10.658	Down-regulation
Atypical_PIKK_ATR_ATR_ST	P35568	IRS1	Q13535	ATR	S741	N734I	734	Missense	distal	-7	no	10.880	10.897	EPSD	COSMIC	10.658	Up-regulation
Atypical_PIKK_ATR_ATR_ST	P35568	IRS1	Q13535	ATR	S741	N734K	734	Missense	distal	-7	no	10.880	11.026	EPSD	COSMIC	10.658	Up-regulation
Atypical_PIKK_ATR_ATR_ST	P35568	IRS1	Q13535	ATR	T743	G739E	739	Missense	distal	-4	no	9.498	11.029	EPSD	COSMIC	10.658	Gain
Atypical_PIKK_ATR_ATR_ST	P35568	IRS1	Q13535	ATR	S892	L885Q	885	Missense	distal	-7	no	11.774	11.924	EPSD	COSMIC	10.658	Up-regulation
Atypical_PIKK_ATR_ATR_ST	P35568	IRS1	Q13535	ATR	T1004	S1011I	1011	Missense	distal	7	no	11.315	11.635	EPSD	COSMIC	10.658	Up-regulation
Atypical_PIKK_ATR_ATR_ST	P35568	IRS1	Q13535	ATR	T1004	R998C	998	Missense	distal	-6	no	11.315	11.302	EPSD	COSMIC;GDSC;CCLE	10.658	Down-regulation
Atypical_PIKK_ATR_ATR_ST	P35568	IRS1	Q13535	ATR	T1004	D1003H	1003	Missense	proximal	-1	no	11.315	11.149	EPSD	COSMIC	10.658	Down-regulation
Atypical_PIKK_ATR_ATR_ST	P35568	IRS1	Q13535	ATR	T1004	P1009S	1009	Missense	distal	5	no	11.315	11.303	EPSD	COSMIC	10.658	Down-regulation
Atypical_PIKK_ATR_ATR_ST	P35568	IRS1	Q13535	ATR	T1004	P997S	997	Missense	distal	-7	no	11.315	11.287	EPSD	COSMIC	10.658	Down-regulation
Atypical_PIKK_ATR_ATR_ST	P35568	IRS1	Q13535	ATR	S1043	A1050V	1050	Missense	distal	7	no	10.644	10.784	EPSD	COSMIC	10.658	Gain
Atypical_PIKK_ATR_ATR_ST	P35568	IRS1	Q13535	ATR	S1134	G1130S	1130	Missense	distal	-4	no	10.245	10.762	EPSD	COSMIC	10.658	Gain
Atypical_PIKK_ATR_ATR_ST	P35568	IRS1	Q13535	ATR	T1196	P1202L	1202	Missense	distal	6	no	12.834	12.907	EPSD	COSMIC	10.658	Up-regulation
Atypical_PIKK_ATR_ATR_ST	P35568	IRS1	Q13535	ATR	S1223	E1224Q	1224	Missense	proximal	1	no	9.939	15.859	EPSD	COSMIC	10.658	Gain
Atypical_PIKK_ATR_ATR_ST	P35568	IRS1	Q13535	ATR	S1223	L1226V	1226	Missense	distal	3	no	9.939	10.705	EPSD	COSMIC	10.658	Gain
Atypical_PIKK_ATR_ATR_ST	O75943	RAD17	Q13535	ATR	T304	N300D	300	Missense	distal	-4	no	11.033	11.643	EPSD	COSMIC	10.658	Up-regulation
Atypical_PIKK_ATR_ATR_ST	O75943	RAD17	Q13535	ATR	T304	N310K	310	Missense	distal	6	no	11.033	10.805	EPSD	COSMIC	10.658	Down-regulation
Atypical_PIKK_ATR_ATR_ST	O75943	RAD17	Q13535	ATR	T633	S628Y	628	Missense	distal	-5	no	12.307	12.635	EPSD	COSMIC	10.658	Up-regulation
Atypical_PIKK_ATR_ATR_ST	O75943	RAD17	Q13535	ATR	S646	P644L	644	Missense	proximal	-2	no	17.814	18.465	EPSD;PhosphoSitePlus	COSMIC	10.658	Up-regulation
Atypical_PIKK_ATR_ATR_ST	Q14191	WRN	Q13535	ATR	S176	H183R	183	Missense	distal	7	no	10.842	10.813	EPSD	COSMIC	10.658	Down-regulation
Atypical_PIKK_ATR_ATR_ST	Q14191	WRN	Q13535	ATR	S409	I404N	404	Missense	distal	-5	no	13.933	13.872	EPSD	COSMIC	10.658	Down-regulation
Atypical_PIKK_ATR_ATR_ST	Q14191	WRN	Q13535	ATR	S409	E406K	406	Missense	distal	-3	no	13.933	13.658	EPSD	COSMIC	10.658	Down-regulation
Atypical_PIKK_ATR_ATR_ST	Q14191	WRN	Q13535	ATR	S478	M473I	473	Missense	distal	-5	no	12.861	13.166	EPSD	COSMIC;GDSC;CCLE	10.658	Up-regulation
Atypical_PIKK_ATR_ATR_ST	Q14191	WRN	Q13535	ATR	S478	S484N	484	Missense	distal	6	no	12.861	12.975	EPSD	COSMIC	10.658	Up-regulation
Atypical_PIKK_ATR_ATR_ST	Q14191	WRN	Q13535	ATR	S478	E480V	480	Missense	proximal	2	no	12.861	12.429	EPSD	COSMIC;GDSC;CCLE	10.658	Down-regulation
Atypical_PIKK_ATR_ATR_ST	Q14191	WRN	Q13535	ATR	S612	L619I	619	Missense	distal	7	no	10.833	10.992	EPSD	COSMIC	10.658	Up-regulation
Atypical_PIKK_ATR_ATR_ST	Q14191	WRN	Q13535	ATR	S1058	Q1059E	1059	Missense	proximal	1	no	14.323	8.403	EPSD	COSMIC;GDSC;CCLE	10.658	Loss
Atypical_PIKK_ATR_ATR_ST	Q14191	WRN	Q13535	ATR	S1141	S1146L	1146	Missense	distal	5	no	16.282	16.289	PhosphoSitePlus	COSMIC	10.658	Up-regulation
Atypical_PIKK_ATR_ATR_ST	Q14191	WRN	Q13535	ATR	S1141	A1137G	1137	Missense	distal	-4	no	16.282	15.244	PhosphoSitePlus	COSMIC	10.658	Down-regulation
Atypical_PIKK_ATR_ATR_ST	Q14191	WRN	Q13535	ATR	S1141	A1147T	1147	Missense	distal	6	no	16.282	16.561	PhosphoSitePlus	COSMIC	10.658	Up-regulation
Atypical_PIKK_ATR_ATR_ST	Q14191	WRN	Q13535	ATR	S1378	P1376S	1376	Missense	proximal	-2	no	11.754	11.703	EPSD	COSMIC	10.658	Down-regulation
Atypical_PIKK_ATR_ATR_ST	Q14191	WRN	Q13535	ATR	S1378	G1377C	1377	Missense	proximal	-1	no	11.754	12.212	EPSD	COSMIC	10.658	Up-regulation
Atypical_PIKK_ATR_ATR_ST	Q14191	WRN	Q13535	ATR	S1378	S1385Y	1385	Missense	distal	7	no	11.754	11.939	EPSD	COSMIC	10.658	Up-regulation
Atypical_PIKK_ATR_ATR_ST	Q14191	WRN	Q13535	ATR	S1378	S1383L	1383	Missense	distal	5	no	11.754	11.761	EPSD	COSMIC	10.658	Up-regulation
Atypical_PIKK_ATR_ATR_ST	Q14191	WRN	Q13535	ATR	S1378	I1381M	1381	Missense	distal	3	no	11.754	11.054	EPSD	COSMIC	10.658	Down-regulation
Atypical_PIKK_ATR_ATR_ST	P49736	MCM2	Q13535	ATR	T39	R33W	33	Missense	distal	-6	no	11.507	11.518	EPSD	COSMIC	10.658	Up-regulation
Atypical_PIKK_ATR_ATR_ST	P49736	MCM2	Q13535	ATR	T39	T39I	39	Missense	central	0	yes	11.507	0.000	EPSD	COSMIC;GDSC	10.658	Loss
Atypical_PIKK_ATR_ATR_ST	P49736	MCM2	Q13535	ATR	T39	R34H	34	Missense	distal	-5	no	11.507	11.445	EPSD	COSMIC	10.658	Down-regulation
Atypical_PIKK_ATR_ATR_ST	P49736	MCM2	Q13535	ATR	S41	T39I	39	Missense	proximal	-2	no	13.128	13.322	EPSD	COSMIC;GDSC	10.658	Up-regulation
Atypical_PIKK_ATR_ATR_ST	P49736	MCM2	Q13535	ATR	S41	R34H	34	Missense	distal	-7	no	13.128	13.179	EPSD	COSMIC	10.658	Up-regulation
Atypical_PIKK_ATR_ATR_ST	P49736	MCM2	Q13535	ATR	S108	E104K	104	Missense	distal	-4	no	15.987	15.577	PhosphoSitePlus	COSMIC	10.658	Down-regulation
Atypical_PIKK_ATR_ATR_ST	P49736	MCM2	Q13535	ATR	S108	R115W	115	Missense	distal	7	no	15.987	16.047	PhosphoSitePlus	COSMIC	10.658	Up-regulation
Atypical_PIKK_ATR_ATR_ST	P49736	MCM2	Q13535	ATR	S108	S108R	108	Missense	central	0	yes	15.987	0.000	PhosphoSitePlus	COSMIC	10.658	Loss
Atypical_PIKK_ATR_ATR_ST	P49736	MCM2	Q13535	ATR	S108	V102I	102	Missense	distal	-6	no	15.987	15.994	PhosphoSitePlus	COSMIC	10.658	Up-regulation
Atypical_PIKK_ATR_ATR_ST	P49736	MCM2	Q13535	ATR	S108	A112T	112	Missense	distal	4	no	15.987	15.737	PhosphoSitePlus	COSMIC;GDSC;CCLE	10.658	Down-regulation
Atypical_PIKK_ATR_ATR_ST	P49736	MCM2	Q13535	ATR	S170	M167V	167	Missense	distal	-3	no	11.079	11.504	EPSD	COSMIC	10.658	Up-regulation
Atypical_PIKK_ATR_ATR_ST	P49736	MCM2	Q13535	ATR	S170	E166D	166	Missense	distal	-4	no	11.079	10.897	EPSD	COSMIC	10.658	Down-regulation
Atypical_PIKK_ATR_ATR_ST	P49736	MCM2	Q13535	ATR	S229	R227H	227	Missense	proximal	-2	no	13.304	12.858	EPSD	COSMIC;GDSC;CCLE	10.658	Down-regulation
Atypical_PIKK_ATR_ATR_ST	P49736	MCM2	Q13535	ATR	S229	E235K	235	Missense	distal	6	no	13.304	13.104	EPSD	COSMIC	10.658	Down-regulation
Atypical_PIKK_ATR_ATR_ST	P49736	MCM2	Q13535	ATR	S541	R542Q	542	Missense	proximal	1	no	8.664	15.659	EPSD	COSMIC	10.658	Gain
Atypical_PIKK_ATR_ATR_ST	P49736	MCM2	Q13535	ATR	S566	R567M	567	Missense	proximal	1	no	8.468	11.378	EPSD	COSMIC;GDSC;CCLE	10.658	Gain
Atypical_PIKK_ATR_ATR_ST	P49736	MCM2	Q13535	ATR	S754	A756V	756	Missense	proximal	2	no	10.365	10.855	EPSD	COSMIC;GDSC	10.658	Gain
Atypical_PIKK_ATR_ATR_ST	P49736	MCM2	Q13535	ATR	S769	T763M	763	Missense	distal	-6	no	10.684	10.663	EPSD	COSMIC	10.658	Down-regulation
Atypical_PIKK_ATR_ATR_ST	P49736	MCM2	Q13535	ATR	S769	I771S	771	Missense	proximal	2	no	10.684	11.357	EPSD	COSMIC	10.658	Up-regulation
Atypical_PIKK_ATR_ATR_ST	P49736	MCM2	Q13535	ATR	S769	H766N	766	Missense	distal	-3	no	10.684	11.600	EPSD	COSMIC	10.658	Up-regulation
Atypical_PIKK_ATR_ATR_ST	P49736	MCM2	Q13535	ATR	T805	V810I	810	Missense	distal	5	no	13.074	13.084	EPSD	COSMIC;GDSC	10.658	Up-regulation
Atypical_PIKK_ATR_ATR_ST	P49736	MCM2	Q13535	ATR	T805	M811T	811	Missense	distal	6	no	13.074	13.366	EPSD	COSMIC	10.658	Up-regulation
Atypical_PIKK_ATR_ATR_ST	O15360	FANCA	Q13535	ATR	T381	T381M	381	Missense	central	0	yes	13.731	0.000	EPSD	COSMIC	10.658	Loss
Atypical_PIKK_ATR_ATR_ST	O15360	FANCA	Q13535	ATR	T381	Q382R	382	Missense	proximal	1	no	13.731	6.736	EPSD	COSMIC	10.658	Loss
Atypical_PIKK_ATR_ATR_ST	O15360	FANCA	Q13535	ATR	T589	L588F	588	Missense	proximal	-1	no	10.940	10.706	EPSD	COSMIC	10.658	Down-regulation
Atypical_PIKK_ATR_ATR_ST	O15360	FANCA	Q13535	ATR	T589	V592A	592	Missense	distal	3	no	10.940	10.179	EPSD	COSMIC	10.658	Loss
Atypical_PIKK_ATR_ATR_ST	O15360	FANCA	Q13535	ATR	T589	L593F	593	Missense	distal	4	no	10.940	10.722	EPSD	COSMIC;GDSC	10.658	Down-regulation
Atypical_PIKK_ATR_ATR_ST	O15360	FANCA	Q13535	ATR	T589	P590T	590	Missense	proximal	1	no	10.940	6.289	EPSD	COSMIC	10.658	Loss
Atypical_PIKK_ATR_ATR_ST	O15360	FANCA	Q13535	ATR	S850	R853Q	853	Missense	distal	3	no	12.143	12.148	EPSD	COSMIC;CCLE	10.658	Up-regulation
Atypical_PIKK_ATR_ATR_ST	O15360	FANCA	Q13535	ATR	S850	K847N	847	Missense	distal	-3	no	12.143	13.303	EPSD	COSMIC	10.658	Up-regulation
Atypical_PIKK_ATR_ATR_ST	O15360	FANCA	Q13535	ATR	S850	K847Q	847	Missense	distal	-3	no	12.143	12.571	EPSD	COSMIC	10.658	Up-regulation
Atypical_PIKK_ATR_ATR_ST	Q9UER7	DAXX	Q13535	ATR	S33	A31V	31	Missense	proximal	-2	no	11.686	11.167	EPSD	COSMIC	10.658	Down-regulation
Atypical_PIKK_ATR_ATR_ST	Q9UER7	DAXX	Q13535	ATR	S41	R48K	48	Missense	distal	7	no	11.270	11.157	EPSD	COSMIC	10.658	Down-regulation
Atypical_PIKK_ATR_ATR_ST	Q9UER7	DAXX	Q13535	ATR	S41	R48T	48	Missense	distal	7	no	11.270	11.218	EPSD	COSMIC	10.658	Down-regulation
Atypical_PIKK_ATR_ATR_ST	Q9UER7	DAXX	Q13535	ATR	S50	S53L	53	Missense	distal	3	no	10.734	10.067	EPSD	COSMIC;GDSC;CCLE	10.658	Loss
Atypical_PIKK_ATR_ATR_ST	Q9UER7	DAXX	Q13535	ATR	S50	R48K	48	Missense	proximal	-2	no	10.734	10.720	EPSD	COSMIC	10.658	Down-regulation
Atypical_PIKK_ATR_ATR_ST	Q9UER7	DAXX	Q13535	ATR	S50	S50N	50	Missense	central	0	yes	10.734	0.000	EPSD	COSMIC	10.658	Loss
Atypical_PIKK_ATR_ATR_ST	Q9UER7	DAXX	Q13535	ATR	S50	R48T	48	Missense	proximal	-2	no	10.734	10.626	EPSD	COSMIC	10.658	Loss
Atypical_PIKK_ATR_ATR_ST	Q9UER7	DAXX	Q13535	ATR	S50	G49R	49	Missense	proximal	-1	no	10.734	10.767	EPSD	COSMIC	10.658	Up-regulation
Atypical_PIKK_ATR_ATR_ST	Q9UER7	DAXX	Q13535	ATR	S50	G54C	54	Missense	distal	4	no	10.734	10.654	EPSD	COSMIC	10.658	Loss
Atypical_PIKK_ATR_ATR_ST	Q9UER7	DAXX	Q13535	ATR	S50	G55D	55	Missense	distal	5	no	10.734	10.738	EPSD	COSMIC	10.658	Up-regulation
Atypical_PIKK_ATR_ATR_ST	Q9UER7	DAXX	Q13535	ATR	S51	S53L	53	Missense	proximal	2	no	11.875	10.909	EPSD	COSMIC;GDSC;CCLE	10.658	Down-regulation
Atypical_PIKK_ATR_ATR_ST	Q9UER7	DAXX	Q13535	ATR	S51	R48K	48	Missense	distal	-3	no	11.875	11.263	EPSD	COSMIC	10.658	Down-regulation
Atypical_PIKK_ATR_ATR_ST	Q9UER7	DAXX	Q13535	ATR	S51	S50N	50	Missense	proximal	-1	no	11.875	12.352	EPSD	COSMIC	10.658	Up-regulation
Atypical_PIKK_ATR_ATR_ST	Q9UER7	DAXX	Q13535	ATR	S51	R48T	48	Missense	distal	-3	no	11.875	11.616	EPSD	COSMIC	10.658	Down-regulation
Atypical_PIKK_ATR_ATR_ST	Q9UER7	DAXX	Q13535	ATR	S51	G49R	49	Missense	proximal	-2	no	11.875	11.971	EPSD	COSMIC	10.658	Up-regulation
Atypical_PIKK_ATR_ATR_ST	Q9UER7	DAXX	Q13535	ATR	S51	G54C	54	Missense	distal	3	no	11.875	12.066	EPSD	COSMIC	10.658	Up-regulation
Atypical_PIKK_ATR_ATR_ST	Q9UER7	DAXX	Q13535	ATR	S51	G55D	55	Missense	distal	4	no	11.875	11.054	EPSD	COSMIC	10.658	Down-regulation
Atypical_PIKK_ATR_ATR_ST	Q9UER7	DAXX	Q13535	ATR	S102	A103S	103	Missense	proximal	1	no	6.613	11.363	EPSD	COSMIC	10.658	Gain
Atypical_PIKK_ATR_ATR_ST	Q9UER7	DAXX	Q13535	ATR	S118	R119Q	119	Missense	proximal	1	no	4.648	11.644	EPSD	COSMIC	10.658	Gain
Atypical_PIKK_ATR_ATR_ST	Q9UER7	DAXX	Q13535	ATR	T151	A146T	146	Missense	distal	-5	no	11.622	11.539	EPSD	COSMIC	10.658	Down-regulation
Atypical_PIKK_ATR_ATR_ST	Q9UER7	DAXX	Q13535	ATR	T151	T150S	150	Missense	proximal	-1	no	11.622	11.575	EPSD	COSMIC	10.658	Down-regulation
Atypical_PIKK_ATR_ATR_ST	Q9UER7	DAXX	Q13535	ATR	S152	A146T	146	Missense	distal	-6	no	10.953	10.931	EPSD	COSMIC	10.658	Down-regulation
Atypical_PIKK_ATR_ATR_ST	Q9UER7	DAXX	Q13535	ATR	S152	T150S	150	Missense	proximal	-2	no	10.953	10.651	EPSD	COSMIC	10.658	Loss
Atypical_PIKK_ATR_ATR_ST	Q9UER7	DAXX	Q13535	ATR	T162	H163Q	163	Missense	proximal	1	no	-1.478	16.040	EPSD	COSMIC	10.658	Gain
Atypical_PIKK_ATR_ATR_ST	Q9UER7	DAXX	Q13535	ATR	S176	Q177E	177	Missense	proximal	1	no	13.958	8.037	EPSD	COSMIC	10.658	Loss
Atypical_PIKK_ATR_ATR_ST	Q9UER7	DAXX	Q13535	ATR	S424	A423T	423	Missense	proximal	-1	no	17.001	16.771	PhosphoSitePlus	COSMIC	10.658	Down-regulation
Atypical_PIKK_ATR_ATR_ST	Q9UER7	DAXX	Q13535	ATR	S424	S429F	429	Missense	distal	5	no	17.001	17.013	PhosphoSitePlus	COSMIC	10.658	Up-regulation
Atypical_PIKK_ATR_ATR_ST	Q9UER7	DAXX	Q13535	ATR	S503	P496T	496	Missense	distal	-7	no	12.280	12.194	EPSD	COSMIC	10.658	Down-regulation
Atypical_PIKK_ATR_ATR_ST	Q9UER7	DAXX	Q13535	ATR	S503	S498P	498	Missense	distal	-5	no	12.280	12.309	EPSD	COSMIC	10.658	Up-regulation
Atypical_PIKK_ATR_ATR_ST	Q9UER7	DAXX	Q13535	ATR	S503	P496L	496	Missense	distal	-7	no	12.280	12.087	EPSD	COSMIC	10.658	Down-regulation
Atypical_PIKK_ATR_ATR_ST	Q9UER7	DAXX	Q13535	ATR	S564	E560Q	560	Missense	distal	-4	no	11.829	10.699	EPSD	COSMIC	10.658	Down-regulation
Atypical_PIKK_ATR_ATR_ST	Q9UER7	DAXX	Q13535	ATR	S564	E568Q	568	Missense	distal	4	no	11.829	11.957	EPSD	COSMIC	10.658	Up-regulation
Atypical_PIKK_ATR_ATR_ST	Q9UER7	DAXX	Q13535	ATR	S564	F567S	567	Missense	distal	3	no	11.829	12.860	EPSD	COSMIC	10.658	Up-regulation
Atypical_PIKK_ATR_ATR_ST	Q9UER7	DAXX	Q13535	ATR	S564	E570D	570	Missense	distal	6	no	11.829	11.555	EPSD	COSMIC	10.658	Down-regulation
Atypical_PIKK_ATR_ATR_ST	Q9UER7	DAXX	Q13535	ATR	S564	L569V	569	Missense	distal	5	no	11.829	11.824	EPSD	COSMIC	10.658	Down-regulation
Atypical_PIKK_ATR_ATR_ST	Q9UER7	DAXX	Q13535	ATR	S564	E559K	559	Missense	distal	-5	no	11.829	11.910	EPSD	COSMIC	10.658	Up-regulation
Atypical_PIKK_ATR_ATR_ST	Q9UER7	DAXX	Q13535	ATR	S588	S593C	593	Missense	distal	5	no	10.670	10.696	EPSD	COSMIC	10.658	Up-regulation
Atypical_PIKK_ATR_ATR_ST	Q9UER7	DAXX	Q13535	ATR	S588	S593N	593	Missense	distal	5	no	10.670	10.675	EPSD	COSMIC	10.658	Up-regulation
Atypical_PIKK_ATR_ATR_ST	Q9UER7	DAXX	Q13535	ATR	S588	S589F	589	Missense	proximal	1	no	10.670	9.963	EPSD	COSMIC	10.658	Loss
Atypical_PIKK_ATR_ATR_ST	Q9UER7	DAXX	Q13535	ATR	S588	S581F	581	Missense	distal	-7	no	10.670	10.562	EPSD	COSMIC	10.658	Loss
Atypical_PIKK_ATR_ATR_ST	Q9UER7	DAXX	Q13535	ATR	S588	T584M	584	Missense	distal	-4	no	10.670	10.537	EPSD	COSMIC	10.658	Loss
Atypical_PIKK_ATR_ATR_ST	Q9UER7	DAXX	Q13535	ATR	S588	S581C	581	Missense	distal	-7	no	10.670	10.445	EPSD	COSMIC	10.658	Loss
Atypical_PIKK_ATR_ATR_ST	Q9UER7	DAXX	Q13535	ATR	S618	H620Q	620	Missense	proximal	2	no	11.540	11.861	EPSD	COSMIC	10.658	Up-regulation
Atypical_PIKK_ATR_ATR_ST	Q9UER7	DAXX	Q13535	ATR	S618	P619S	619	Missense	proximal	1	no	11.540	10.431	EPSD	COSMIC	10.658	Loss
Atypical_PIKK_ATR_ATR_ST	Q9UER7	DAXX	Q13535	ATR	S618	W622C	622	Missense	distal	4	no	11.540	11.847	EPSD	COSMIC	10.658	Up-regulation
Atypical_PIKK_ATR_ATR_ST	Q9UER7	DAXX	Q13535	ATR	S618	S612F	612	Missense	distal	-6	no	11.540	11.620	EPSD	COSMIC	10.658	Up-regulation
Atypical_PIKK_ATR_ATR_ST	Q9UER7	DAXX	Q13535	ATR	S618	D624G	624	Missense	distal	6	no	11.540	11.487	EPSD	COSMIC	10.658	Down-regulation
Atypical_PIKK_ATR_ATR_ST	Q9UER7	DAXX	Q13535	ATR	S618	G623R	623	Missense	distal	5	no	11.540	11.546	EPSD	COSMIC	10.658	Up-regulation
Atypical_PIKK_ATR_ATR_ST	Q9UER7	DAXX	Q13535	ATR	T665	C664R	664	Missense	proximal	-1	no	10.695	10.270	EPSD	COSMIC	10.658	Loss
Atypical_PIKK_ATR_ATR_ST	Q9UER7	DAXX	Q13535	ATR	T665	S668C	668	Missense	distal	3	no	10.695	10.392	EPSD	COSMIC	10.658	Loss
Atypical_PIKK_ATR_ATR_ST	Q9UER7	DAXX	Q13535	ATR	T665	S668N	668	Missense	distal	3	no	10.695	10.440	EPSD	COSMIC	10.658	Loss
Atypical_PIKK_ATR_ATR_ST	Q9UER7	DAXX	Q13535	ATR	T665	T665I	665	Missense	central	0	yes	10.695	0.000	EPSD	COSMIC	10.658	Loss
Atypical_PIKK_ATR_ATR_ST	Q9UER7	DAXX	Q13535	ATR	S688	S688C	688	Missense	central	0	yes	11.222	0.000	EPSD	COSMIC	10.658	Loss
Atypical_PIKK_ATR_ATR_ST	Q9UER7	DAXX	Q13535	ATR	S688	S682F	682	Missense	distal	-6	no	11.222	11.302	EPSD	COSMIC	10.658	Up-regulation
Atypical_PIKK_ATR_ATR_ST	Q9UER7	DAXX	Q13535	ATR	S707	R705W	705	Missense	proximal	-2	no	10.780	10.886	EPSD	COSMIC;GDSC;CCLE	10.658	Up-regulation
Atypical_PIKK_ATR_ATR_ST	Q9UER7	DAXX	Q13535	ATR	S707	H711Y	711	Missense	distal	4	no	10.780	11.636	EPSD	COSMIC	10.658	Up-regulation
Atypical_PIKK_ATR_ATR_ST	Q9UER7	DAXX	Q13535	ATR	S707	R705L	705	Missense	proximal	-2	no	10.780	11.074	EPSD	COSMIC	10.658	Up-regulation
Atypical_PIKK_ATR_ATR_ST	Q9UER7	DAXX	Q13535	ATR	S707	P703S	703	Missense	distal	-4	no	10.780	10.455	EPSD	COSMIC	10.658	Loss
Atypical_PIKK_ATR_ATR_ST	Q9UER7	DAXX	Q13535	ATR	S712	R705W	705	Missense	distal	-7	no	15.607	15.549	EPSD	COSMIC;GDSC;CCLE	10.658	Down-regulation
Atypical_PIKK_ATR_ATR_ST	Q9UER7	DAXX	Q13535	ATR	S712	H711Y	711	Missense	proximal	-1	no	15.607	15.918	EPSD	COSMIC	10.658	Up-regulation
Atypical_PIKK_ATR_ATR_ST	Q9UER7	DAXX	Q13535	ATR	S712	R705L	705	Missense	distal	-7	no	15.607	15.489	EPSD	COSMIC	10.658	Down-regulation
Atypical_PIKK_ATR_ATR_ST	Q03164	KMT2A	Q13535	ATR	S153	G152D	152	Missense	proximal	-1	no	10.699	10.792	EPSD	COSMIC	10.658	Up-regulation
Atypical_PIKK_ATR_ATR_ST	Q03164	KMT2A	Q13535	ATR	S153	F151Y	151	Missense	proximal	-2	no	10.699	10.940	EPSD	COSMIC	10.658	Up-regulation
Atypical_PIKK_ATR_ATR_ST	Q03164	KMT2A	Q13535	ATR	S153	R158T	158	Missense	distal	5	no	10.699	10.696	EPSD	COSMIC	10.658	Down-regulation
Atypical_PIKK_ATR_ATR_ST	Q03164	KMT2A	Q13535	ATR	S153	G150R	150	Missense	distal	-3	no	10.699	11.195	EPSD	COSMIC	10.658	Up-regulation
Atypical_PIKK_ATR_ATR_ST	Q03164	KMT2A	Q13535	ATR	S153	F148V	148	Missense	distal	-5	no	10.699	10.571	EPSD	COSMIC	10.658	Loss
Atypical_PIKK_ATR_ATR_ST	Q03164	KMT2A	Q13535	ATR	S202	S197F	197	Missense	distal	-5	no	11.115	11.342	EPSD	COSMIC	10.658	Up-regulation
Atypical_PIKK_ATR_ATR_ST	Q03164	KMT2A	Q13535	ATR	S202	K209Q	209	Missense	distal	7	no	11.115	11.027	EPSD	COSMIC	10.658	Down-regulation
Atypical_PIKK_ATR_ATR_ST	Q03164	KMT2A	Q13535	ATR	S202	K201I	201	Missense	proximal	-1	no	11.115	11.495	EPSD	COSMIC	10.658	Up-regulation
Atypical_PIKK_ATR_ATR_ST	Q03164	KMT2A	Q13535	ATR	S202	D208H	208	Missense	distal	6	no	11.115	10.983	EPSD	COSMIC	10.658	Down-regulation
Atypical_PIKK_ATR_ATR_ST	Q03164	KMT2A	Q13535	ATR	S252	K257R	257	Missense	distal	5	no	12.089	12.096	EPSD	COSMIC	10.658	Up-regulation
Atypical_PIKK_ATR_ATR_ST	Q03164	KMT2A	Q13535	ATR	S252	K249N	249	Missense	distal	-3	no	12.089	13.249	EPSD	COSMIC	10.658	Up-regulation
Atypical_PIKK_ATR_ATR_ST	Q03164	KMT2A	Q13535	ATR	S252	I256V	256	Missense	distal	4	no	12.089	11.569	EPSD	COSMIC	10.658	Down-regulation
Atypical_PIKK_ATR_ATR_ST	Q03164	KMT2A	Q13535	ATR	S279	L281F	281	Missense	proximal	2	no	12.300	10.577	EPSD	COSMIC	10.658	Loss
Atypical_PIKK_ATR_ATR_ST	Q03164	KMT2A	Q13535	ATR	S279	K284Q	284	Missense	distal	5	no	12.300	12.297	EPSD	COSMIC	10.658	Down-regulation
Atypical_PIKK_ATR_ATR_ST	Q03164	KMT2A	Q13535	ATR	S279	L273I	273	Missense	distal	-6	no	12.300	12.274	EPSD	COSMIC	10.658	Down-regulation
Atypical_PIKK_ATR_ATR_ST	Q03164	KMT2A	Q13535	ATR	S322	E323Q	323	Missense	proximal	1	no	9.728	15.648	EPSD	COSMIC	10.658	Gain
Atypical_PIKK_ATR_ATR_ST	Q03164	KMT2A	Q13535	ATR	S470	Q471E	471	Missense	proximal	1	no	14.231	8.310	EPSD	COSMIC	10.658	Loss
Atypical_PIKK_ATR_ATR_ST	Q03164	KMT2A	Q13535	ATR	S470	H468N	468	Missense	proximal	-2	no	14.231	15.115	EPSD	COSMIC	10.658	Up-regulation
Atypical_PIKK_ATR_ATR_ST	Q03164	KMT2A	Q13535	ATR	S470	Q467L	467	Missense	distal	-3	no	14.231	14.449	EPSD	COSMIC	10.658	Up-regulation
Atypical_PIKK_ATR_ATR_ST	Q03164	KMT2A	Q13535	ATR	S470	S466C	466	Missense	distal	-4	no	14.231	12.941	EPSD	COSMIC	10.658	Down-regulation
Atypical_PIKK_ATR_ATR_ST	Q03164	KMT2A	Q13535	ATR	S470	S477C	477	Missense	distal	7	no	14.231	14.593	EPSD	COSMIC	10.658	Up-regulation
Atypical_PIKK_ATR_ATR_ST	Q03164	KMT2A	Q13535	ATR	S470	S474L	474	Missense	distal	4	no	14.231	14.468	EPSD	COSMIC	10.658	Up-regulation
Atypical_PIKK_ATR_ATR_ST	Q03164	KMT2A	Q13535	ATR	S481	S477C	477	Missense	distal	-4	no	12.718	11.428	EPSD	COSMIC	10.658	Down-regulation
Atypical_PIKK_ATR_ATR_ST	Q03164	KMT2A	Q13535	ATR	S481	S474L	474	Missense	distal	-7	no	12.718	12.552	EPSD	COSMIC	10.658	Down-regulation
Atypical_PIKK_ATR_ATR_ST	Q03164	KMT2A	Q13535	ATR	T506	L499F	499	Missense	distal	-7	no	11.364	11.422	EPSD	COSMIC	10.658	Up-regulation
Atypical_PIKK_ATR_ATR_ST	Q03164	KMT2A	Q13535	ATR	T506	P500T	500	Missense	distal	-6	no	11.364	11.405	EPSD	COSMIC	10.658	Up-regulation
Atypical_PIKK_ATR_ATR_ST	Q03164	KMT2A	Q13535	ATR	T506	P500S	500	Missense	distal	-6	no	11.364	11.319	EPSD	COSMIC	10.658	Down-regulation
Atypical_PIKK_ATR_ATR_ST	Q03164	KMT2A	Q13535	ATR	T506	P507S	507	Missense	proximal	1	no	11.364	10.255	EPSD	COSMIC	10.658	Loss
Atypical_PIKK_ATR_ATR_ST	Q03164	KMT2A	Q13535	ATR	T506	T506I	506	Missense	central	0	yes	11.364	0.000	EPSD	COSMIC	10.658	Loss
Atypical_PIKK_ATR_ATR_ST	Q03164	KMT2A	Q13535	ATR	S534	E535Q	535	Missense	proximal	1	no	8.360	14.281	EPSD	COSMIC	10.658	Gain
Atypical_PIKK_ATR_ATR_ST	Q03164	KMT2A	Q13535	ATR	S627	P629S	629	Missense	proximal	2	no	11.319	11.003	EPSD	COSMIC	10.658	Down-regulation
Atypical_PIKK_ATR_ATR_ST	Q03164	KMT2A	Q13535	ATR	T703	P704L	704	Missense	proximal	1	no	10.803	10.238	EPSD	COSMIC	10.658	Loss
Atypical_PIKK_ATR_ATR_ST	Q03164	KMT2A	Q13535	ATR	T703	H708P	708	Missense	distal	5	no	10.803	10.810	EPSD	COSMIC	10.658	Up-regulation
Atypical_PIKK_ATR_ATR_ST	Q03164	KMT2A	Q13535	ATR	T703	A699T	699	Missense	distal	-4	no	10.803	10.196	EPSD	COSMIC	10.658	Loss
Atypical_PIKK_ATR_ATR_ST	Q03164	KMT2A	Q13535	ATR	S843	Q844H	844	Missense	proximal	1	no	15.502	-2.016	EPSD	COSMIC	10.658	Loss
Atypical_PIKK_ATR_ATR_ST	Q03164	KMT2A	Q13535	ATR	S867	V868M	868	Missense	proximal	1	no	-3.831	11.779	EPSD	COSMIC;GDSC;CCLE	10.658	Gain
Atypical_PIKK_ATR_ATR_ST	Q03164	KMT2A	Q13535	ATR	S982	L983M	983	Missense	proximal	1	no	10.441	11.789	EPSD	COSMIC	10.658	Gain
Atypical_PIKK_ATR_ATR_ST	Q03164	KMT2A	Q13535	ATR	S1059	Q1054E	1054	Missense	distal	-5	no	10.822	10.649	EPSD	COSMIC	10.658	Loss
Atypical_PIKK_ATR_ATR_ST	Q03164	KMT2A	Q13535	ATR	S1059	S1062Y	1062	Missense	distal	3	no	10.822	9.905	EPSD	COSMIC;GDSC;CCLE	10.658	Loss
Atypical_PIKK_ATR_ATR_ST	Q03164	KMT2A	Q13535	ATR	S1059	S1062F	1062	Missense	distal	3	no	10.822	9.791	EPSD	COSMIC	10.658	Loss
Atypical_PIKK_ATR_ATR_ST	Q03164	KMT2A	Q13535	ATR	S1059	T1061S	1061	Missense	proximal	2	no	10.822	11.213	EPSD	COSMIC	10.658	Up-regulation
Atypical_PIKK_ATR_ATR_ST	Q03164	KMT2A	Q13535	ATR	S1059	P1066S	1066	Missense	distal	7	no	10.822	10.659	EPSD	COSMIC	10.658	Down-regulation
Atypical_PIKK_ATR_ATR_ST	Q03164	KMT2A	Q13535	ATR	S1107	D1111V	1111	Missense	distal	4	no	14.530	14.745	EPSD	COSMIC	10.658	Up-regulation
Atypical_PIKK_ATR_ATR_ST	Q03164	KMT2A	Q13535	ATR	S1107	R1101Q	1101	Missense	distal	-6	no	14.530	14.522	EPSD	COSMIC	10.658	Down-regulation
Atypical_PIKK_ATR_ATR_ST	Q03164	KMT2A	Q13535	ATR	S1241	T1245P	1245	Missense	distal	4	no	13.064	13.100	EPSD	COSMIC	10.658	Up-regulation
Atypical_PIKK_ATR_ATR_ST	Q03164	KMT2A	Q13535	ATR	S1241	V1237M	1237	Missense	distal	-4	no	13.064	13.313	EPSD	COSMIC	10.658	Up-regulation
Atypical_PIKK_ATR_ATR_ST	Q03164	KMT2A	Q13535	ATR	S1241	K1235T	1235	Missense	distal	-6	no	13.064	13.141	EPSD	COSMIC	10.658	Up-regulation
Atypical_PIKK_ATR_ATR_ST	Q03164	KMT2A	Q13535	ATR	S1241	A1248S	1248	Missense	distal	7	no	13.064	12.994	EPSD	COSMIC	10.658	Down-regulation
Atypical_PIKK_ATR_ATR_ST	Q03164	KMT2A	Q13535	ATR	S1299	K1293T	1293	Missense	distal	-6	no	15.557	15.634	EPSD	COSMIC	10.658	Up-regulation
Atypical_PIKK_ATR_ATR_ST	Q03164	KMT2A	Q13535	ATR	S1299	L1303V	1303	Missense	distal	4	no	15.557	15.483	EPSD	COSMIC	10.658	Down-regulation
Atypical_PIKK_ATR_ATR_ST	Q03164	KMT2A	Q13535	ATR	S1299	L1303P	1303	Missense	distal	4	no	15.557	15.407	EPSD	COSMIC	10.658	Down-regulation
Atypical_PIKK_ATR_ATR_ST	Q03164	KMT2A	Q13535	ATR	T1382	S1388T	1388	Missense	distal	6	no	11.561	11.514	EPSD	COSMIC	10.658	Down-regulation
Atypical_PIKK_ATR_ATR_ST	Q03164	KMT2A	Q13535	ATR	T1382	T1376S	1376	Missense	distal	-6	no	11.561	11.475	EPSD	COSMIC	10.658	Down-regulation
Atypical_PIKK_ATR_ATR_ST	Q03164	KMT2A	Q13535	ATR	T1382	S1389F	1389	Missense	distal	7	no	11.561	11.623	EPSD	COSMIC	10.658	Up-regulation
Atypical_PIKK_ATR_ATR_ST	Q03164	KMT2A	Q13535	ATR	T1382	S1384P	1384	Missense	proximal	2	no	11.561	11.877	EPSD	COSMIC;CCLE	10.658	Up-regulation
Atypical_PIKK_ATR_ATR_ST	Q03164	KMT2A	Q13535	ATR	T1382	S1388G	1388	Missense	distal	6	no	11.561	11.319	EPSD	COSMIC	10.658	Down-regulation
Atypical_PIKK_ATR_ATR_ST	Q03164	KMT2A	Q13535	ATR	T1695	P1692A	1692	Missense	distal	-3	no	11.783	12.346	EPSD	COSMIC	10.658	Up-regulation
Atypical_PIKK_ATR_ATR_ST	Q03164	KMT2A	Q13535	ATR	T1695	S1698I	1698	Missense	distal	3	no	11.783	11.793	EPSD	COSMIC	10.658	Up-regulation
Atypical_PIKK_ATR_ATR_ST	Q03164	KMT2A	Q13535	ATR	T1695	L1694F	1694	Missense	proximal	-1	no	11.783	11.550	EPSD	COSMIC	10.658	Down-regulation
Atypical_PIKK_ATR_ATR_ST	Q03164	KMT2A	Q13535	ATR	T1695	E1696Q	1696	Missense	proximal	1	no	11.783	17.704	EPSD	COSMIC	10.658	Up-regulation
Atypical_PIKK_ATR_ATR_ST	Q03164	KMT2A	Q13535	ATR	T1695	D1690H	1690	Missense	distal	-5	no	11.783	11.736	EPSD	COSMIC	10.658	Down-regulation
Atypical_PIKK_ATR_ATR_ST	Q03164	KMT2A	Q13535	ATR	T1851	P1847S	1847	Missense	distal	-4	no	12.036	11.711	EPSD	COSMIC	10.658	Down-regulation
Atypical_PIKK_ATR_ATR_ST	Q03164	KMT2A	Q13535	ATR	T1851	P1846S	1846	Missense	distal	-5	no	12.036	12.007	EPSD	COSMIC	10.658	Down-regulation
Atypical_PIKK_ATR_ATR_ST	Q03164	KMT2A	Q13535	ATR	T1851	I1848V	1848	Missense	distal	-3	no	12.036	12.453	EPSD	COSMIC	10.658	Up-regulation
Atypical_PIKK_ATR_ATR_ST	Q03164	KMT2A	Q13535	ATR	T1851	R1855Q	1855	Missense	distal	4	no	12.036	11.870	EPSD	COSMIC	10.658	Down-regulation
Atypical_PIKK_ATR_ATR_ST	Q03164	KMT2A	Q13535	ATR	T1851	T1845I	1845	Missense	distal	-6	no	12.036	12.034	EPSD	COSMIC	10.658	Down-regulation
Atypical_PIKK_ATR_ATR_ST	Q03164	KMT2A	Q13535	ATR	T1851	D1852H	1852	Missense	proximal	1	no	12.036	-0.068	EPSD	COSMIC	10.658	Loss
Atypical_PIKK_ATR_ATR_ST	Q03164	KMT2A	Q13535	ATR	T1851	P1844S	1844	Missense	distal	-7	no	12.036	12.009	EPSD	COSMIC	10.658	Down-regulation
Atypical_PIKK_ATR_ATR_ST	Q03164	KMT2A	Q13535	ATR	S1854	R1855Q	1855	Missense	proximal	1	no	8.528	15.524	EPSD	COSMIC	10.658	Gain
Atypical_PIKK_ATR_ATR_ST	Q03164	KMT2A	Q13535	ATR	S1858	R1855Q	1855	Missense	distal	-3	no	11.851	11.667	EPSD	COSMIC	10.658	Down-regulation
Atypical_PIKK_ATR_ATR_ST	Q03164	KMT2A	Q13535	ATR	S1858	E1860D	1860	Missense	proximal	2	no	11.851	10.175	EPSD	COSMIC	10.658	Loss
Atypical_PIKK_ATR_ATR_ST	Q03164	KMT2A	Q13535	ATR	S1858	N1862K	1862	Missense	distal	4	no	11.851	11.082	EPSD	COSMIC	10.658	Down-regulation
Atypical_PIKK_ATR_ATR_ST	Q03164	KMT2A	Q13535	ATR	S1858	D1852H	1852	Missense	distal	-6	no	11.851	11.876	EPSD	COSMIC	10.658	Up-regulation
Atypical_PIKK_ATR_ATR_ST	Q03164	KMT2A	Q13535	ATR	S1858	P1864S	1864	Missense	distal	6	no	11.851	12.148	EPSD	COSMIC	10.658	Up-regulation
Atypical_PIKK_ATR_ATR_ST	Q03164	KMT2A	Q13535	ATR	S2118	P2125S	2125	Missense	distal	7	no	11.870	11.707	EPSD	COSMIC	10.658	Down-regulation
Atypical_PIKK_ATR_ATR_ST	Q03164	KMT2A	Q13535	ATR	S2118	P2122S	2122	Missense	distal	4	no	11.870	11.784	EPSD	COSMIC	10.658	Down-regulation
Atypical_PIKK_ATR_ATR_ST	Q03164	KMT2A	Q13535	ATR	S2118	R2124Q	2124	Missense	distal	6	no	11.870	12.139	EPSD	COSMIC	10.658	Up-regulation
Atypical_PIKK_ATR_ATR_ST	Q03164	KMT2A	Q13535	ATR	S2128	P2125S	2125	Missense	distal	-3	no	15.525	15.248	EPSD	COSMIC	10.658	Down-regulation
Atypical_PIKK_ATR_ATR_ST	Q03164	KMT2A	Q13535	ATR	S2128	P2122S	2122	Missense	distal	-6	no	15.525	15.479	EPSD	COSMIC	10.658	Down-regulation
Atypical_PIKK_ATR_ATR_ST	Q03164	KMT2A	Q13535	ATR	S2128	R2124Q	2124	Missense	distal	-4	no	15.525	15.706	EPSD	COSMIC	10.658	Up-regulation
Atypical_PIKK_ATR_ATR_ST	Q03164	KMT2A	Q13535	ATR	S2128	S2133F	2133	Missense	distal	5	no	15.525	15.537	EPSD	COSMIC	10.658	Up-regulation
Atypical_PIKK_ATR_ATR_ST	Q03164	KMT2A	Q13535	ATR	S2128	S2131F	2131	Missense	distal	3	no	15.525	14.493	EPSD	COSMIC	10.658	Down-regulation
Atypical_PIKK_ATR_ATR_ST	Q03164	KMT2A	Q13535	ATR	S2149	I2145T	2145	Missense	distal	-4	no	9.480	10.736	EPSD	COSMIC	10.658	Gain
Atypical_PIKK_ATR_ATR_ST	Q03164	KMT2A	Q13535	ATR	T2153	P2148L	2148	Missense	distal	-5	no	11.254	11.407	EPSD	COSMIC	10.658	Up-regulation
Atypical_PIKK_ATR_ATR_ST	Q03164	KMT2A	Q13535	ATR	T2153	G2158D	2158	Missense	distal	5	no	11.254	11.258	EPSD	COSMIC	10.658	Up-regulation
Atypical_PIKK_ATR_ATR_ST	Q03164	KMT2A	Q13535	ATR	T2153	S2156F	2156	Missense	distal	3	no	11.254	10.223	EPSD	COSMIC	10.658	Loss
Atypical_PIKK_ATR_ATR_ST	Q03164	KMT2A	Q13535	ATR	T2153	P2148S	2148	Missense	distal	-5	no	11.254	11.224	EPSD	COSMIC	10.658	Down-regulation
Atypical_PIKK_ATR_ATR_ST	Q03164	KMT2A	Q13535	ATR	T2153	R2146Q	2146	Missense	distal	-7	no	11.254	11.285	EPSD	COSMIC	10.658	Up-regulation
Atypical_PIKK_ATR_ATR_ST	Q03164	KMT2A	Q13535	ATR	T2153	S2149R	2149	Missense	distal	-4	no	11.254	10.956	EPSD	COSMIC	10.658	Down-regulation
Atypical_PIKK_ATR_ATR_ST	Q03164	KMT2A	Q13535	ATR	T2153	S2149G	2149	Missense	distal	-4	no	11.254	10.736	EPSD	COSMIC	10.658	Down-regulation
Atypical_PIKK_ATR_ATR_ST	Q03164	KMT2A	Q13535	ATR	S2184	T2177I	2177	Missense	distal	-7	no	11.859	11.800	EPSD	COSMIC	10.658	Down-regulation
Atypical_PIKK_ATR_ATR_ST	Q03164	KMT2A	Q13535	ATR	S2184	G2179C	2179	Missense	distal	-5	no	11.859	12.032	EPSD	COSMIC	10.658	Up-regulation
Atypical_PIKK_ATR_ATR_ST	Q03164	KMT2A	Q13535	ATR	S2184	V2178A	2178	Missense	distal	-6	no	11.859	11.890	EPSD	COSMIC;GDSC;CCLE	10.658	Up-regulation
Atypical_PIKK_ATR_ATR_ST	Q03164	KMT2A	Q13535	ATR	S2255	T2260I	2260	Missense	distal	5	no	11.494	11.498	EPSD	COSMIC	10.658	Up-regulation
Atypical_PIKK_ATR_ATR_ST	Q03164	KMT2A	Q13535	ATR	S2255	P2249S	2249	Missense	distal	-6	no	11.494	11.449	EPSD	COSMIC	10.658	Down-regulation
Atypical_PIKK_ATR_ATR_ST	Q03164	KMT2A	Q13535	ATR	S2255	Q2258K	2258	Missense	distal	3	no	11.494	11.767	EPSD	COSMIC	10.658	Up-regulation
Atypical_PIKK_ATR_ATR_ST	Q03164	KMT2A	Q13535	ATR	S2255	S2261F	2261	Missense	distal	6	no	11.494	11.336	EPSD	COSMIC	10.658	Down-regulation
Atypical_PIKK_ATR_ATR_ST	Q03164	KMT2A	Q13535	ATR	S2391	E2398K	2398	Missense	distal	7	no	10.968	11.117	EPSD	COSMIC	10.658	Up-regulation
Atypical_PIKK_ATR_ATR_ST	Q03164	KMT2A	Q13535	ATR	S2391	E2395K	2395	Missense	distal	4	no	10.968	11.079	EPSD	COSMIC	10.658	Up-regulation
Atypical_PIKK_ATR_ATR_ST	Q03164	KMT2A	Q13535	ATR	S2391	S2392P	2392	Missense	proximal	1	no	10.968	12.078	EPSD	COSMIC;GDSC	10.658	Up-regulation
Atypical_PIKK_ATR_ATR_ST	Q03164	KMT2A	Q13535	ATR	S2391	S2391P	2391	Missense	central	0	yes	10.968	0.000	EPSD	COSMIC	10.658	Loss
Atypical_PIKK_ATR_ATR_ST	Q03164	KMT2A	Q13535	ATR	S2391	D2384E	2384	Missense	distal	-7	no	10.968	11.014	EPSD	COSMIC	10.658	Up-regulation
Atypical_PIKK_ATR_ATR_ST	Q03164	KMT2A	Q13535	ATR	S2392	E2398K	2398	Missense	distal	6	no	11.195	10.996	EPSD	COSMIC	10.658	Down-regulation
Atypical_PIKK_ATR_ATR_ST	Q03164	KMT2A	Q13535	ATR	S2392	E2395K	2395	Missense	distal	3	no	11.195	11.352	EPSD	COSMIC	10.658	Up-regulation
Atypical_PIKK_ATR_ATR_ST	Q03164	KMT2A	Q13535	ATR	S2392	S2392P	2392	Missense	central	0	yes	11.195	0.000	EPSD	COSMIC;GDSC	10.658	Loss
Atypical_PIKK_ATR_ATR_ST	Q03164	KMT2A	Q13535	ATR	S2392	S2391P	2391	Missense	proximal	-1	no	11.195	11.410	EPSD	COSMIC	10.658	Up-regulation
Atypical_PIKK_ATR_ATR_ST	Q03164	KMT2A	Q13535	ATR	S2493	P2498H	2498	Missense	distal	5	no	12.863	12.856	EPSD	COSMIC	10.658	Down-regulation
Atypical_PIKK_ATR_ATR_ST	Q03164	KMT2A	Q13535	ATR	S2493	L2492F	2492	Missense	proximal	-1	no	12.863	12.629	EPSD	COSMIC	10.658	Down-regulation
Atypical_PIKK_ATR_ATR_ST	Q03164	KMT2A	Q13535	ATR	S2493	K2486T	2486	Missense	distal	-7	no	12.863	12.792	EPSD	COSMIC	10.658	Down-regulation
Atypical_PIKK_ATR_ATR_ST	Q03164	KMT2A	Q13535	ATR	S2533	E2532D	2532	Missense	proximal	-1	no	12.191	12.236	EPSD	COSMIC	10.658	Up-regulation
Atypical_PIKK_ATR_ATR_ST	Q03164	KMT2A	Q13535	ATR	S2533	A2538S	2538	Missense	distal	5	no	12.191	12.179	EPSD	COSMIC	10.658	Down-regulation
Atypical_PIKK_ATR_ATR_ST	Q03164	KMT2A	Q13535	ATR	S2533	E2530K	2530	Missense	distal	-3	no	12.191	11.915	EPSD	COSMIC	10.658	Down-regulation
Atypical_PIKK_ATR_ATR_ST	Q03164	KMT2A	Q13535	ATR	S2625	T2632I	2632	Missense	distal	7	no	10.566	10.714	EPSD	COSMIC	10.658	Gain
Atypical_PIKK_ATR_ATR_ST	Q03164	KMT2A	Q13535	ATR	T2632	P2633Q	2633	Missense	proximal	1	no	8.051	12.919	EPSD	COSMIC	10.658	Gain
Atypical_PIKK_ATR_ATR_ST	Q03164	KMT2A	Q13535	ATR	S2650	T2652A	2652	Missense	proximal	2	no	10.714	11.252	EPSD	COSMIC	10.658	Up-regulation
Atypical_PIKK_ATR_ATR_ST	Q03164	KMT2A	Q13535	ATR	S2650	P2646L	2646	Missense	distal	-4	no	10.714	9.514	EPSD	COSMIC	10.658	Loss
Atypical_PIKK_ATR_ATR_ST	Q03164	KMT2A	Q13535	ATR	S2650	R2656Q	2656	Missense	distal	6	no	10.714	10.982	EPSD	COSMIC	10.658	Up-regulation
Atypical_PIKK_ATR_ATR_ST	Q03164	KMT2A	Q13535	ATR	S2650	T2652I	2652	Missense	proximal	2	no	10.714	10.431	EPSD	COSMIC	10.658	Loss
Atypical_PIKK_ATR_ATR_ST	Q03164	KMT2A	Q13535	ATR	S2650	T2652S	2652	Missense	proximal	2	no	10.714	11.105	EPSD	COSMIC	10.658	Up-regulation
Atypical_PIKK_ATR_ATR_ST	Q03164	KMT2A	Q13535	ATR	S2650	I2645L	2645	Missense	distal	-5	no	10.714	10.693	EPSD	COSMIC	10.658	Down-regulation
Atypical_PIKK_ATR_ATR_ST	Q03164	KMT2A	Q13535	ATR	S2650	P2646Q	2646	Missense	distal	-4	no	10.714	10.273	EPSD	COSMIC	10.658	Loss
Atypical_PIKK_ATR_ATR_ST	Q03164	KMT2A	Q13535	ATR	S2650	R2656P	2656	Missense	distal	6	no	10.714	10.813	EPSD	COSMIC	10.658	Up-regulation
Atypical_PIKK_ATR_ATR_ST	Q03164	KMT2A	Q13535	ATR	T2791	S2796F	2796	Missense	distal	5	no	14.316	14.328	EPSD	COSMIC	10.658	Up-regulation
Atypical_PIKK_ATR_ATR_ST	Q03164	KMT2A	Q13535	ATR	T2791	S2785C	2785	Missense	distal	-6	no	14.316	14.385	EPSD	COSMIC	10.658	Up-regulation
Atypical_PIKK_ATR_ATR_ST	Q03164	KMT2A	Q13535	ATR	T2791	Q2794H	2794	Missense	distal	3	no	14.316	14.719	EPSD	COSMIC	10.658	Up-regulation
Atypical_PIKK_ATR_ATR_ST	Q03164	KMT2A	Q13535	ATR	T2791	S2785Y	2785	Missense	distal	-6	no	14.316	14.489	EPSD	COSMIC	10.658	Up-regulation
Atypical_PIKK_ATR_ATR_ST	Q03164	KMT2A	Q13535	ATR	S2859	G2864D	2864	Missense	distal	5	no	10.897	10.902	EPSD	COSMIC	10.658	Up-regulation
Atypical_PIKK_ATR_ATR_ST	Q03164	KMT2A	Q13535	ATR	S2859	S2866R	2866	Missense	distal	7	no	10.897	11.121	EPSD	COSMIC	10.658	Up-regulation
Atypical_PIKK_ATR_ATR_ST	Q03164	KMT2A	Q13535	ATR	S2859	K2855N	2855	Missense	distal	-4	no	10.897	10.517	EPSD	COSMIC	10.658	Loss
Atypical_PIKK_ATR_ATR_ST	Q03164	KMT2A	Q13535	ATR	S2859	T2857I	2857	Missense	proximal	-2	no	10.897	11.092	EPSD	COSMIC	10.658	Up-regulation
Atypical_PIKK_ATR_ATR_ST	Q03164	KMT2A	Q13535	ATR	S2859	A2862V	2862	Missense	distal	3	no	10.897	11.658	EPSD	COSMIC	10.658	Up-regulation
Atypical_PIKK_ATR_ATR_ST	Q03164	KMT2A	Q13535	ATR	S2866	S2869R	2869	Missense	distal	3	no	13.147	12.711	EPSD	COSMIC	10.658	Down-regulation
Atypical_PIKK_ATR_ATR_ST	Q03164	KMT2A	Q13535	ATR	S2866	S2872L	2872	Missense	distal	6	no	13.147	12.922	EPSD	COSMIC	10.658	Down-regulation
Atypical_PIKK_ATR_ATR_ST	Q03164	KMT2A	Q13535	ATR	S2866	G2864D	2864	Missense	proximal	-2	no	13.147	13.226	EPSD	COSMIC	10.658	Up-regulation
Atypical_PIKK_ATR_ATR_ST	Q03164	KMT2A	Q13535	ATR	S2866	E2868K	2868	Missense	proximal	2	no	13.147	12.198	EPSD	COSMIC	10.658	Down-regulation
Atypical_PIKK_ATR_ATR_ST	Q03164	KMT2A	Q13535	ATR	S2866	S2866R	2866	Missense	central	0	yes	13.147	0.000	EPSD	COSMIC	10.658	Loss
Atypical_PIKK_ATR_ATR_ST	Q03164	KMT2A	Q13535	ATR	S2866	A2862V	2862	Missense	distal	-4	no	13.147	12.158	EPSD	COSMIC	10.658	Down-regulation
Atypical_PIKK_ATR_ATR_ST	Q03164	KMT2A	Q13535	ATR	S2866	E2873Q	2873	Missense	distal	7	no	13.147	13.207	EPSD	COSMIC	10.658	Up-regulation
Atypical_PIKK_ATR_ATR_ST	Q03164	KMT2A	Q13535	ATR	S2872	E2873Q	2873	Missense	proximal	1	no	7.673	13.593	EPSD	COSMIC	10.658	Gain
Atypical_PIKK_ATR_ATR_ST	Q03164	KMT2A	Q13535	ATR	T2936	R2937Q	2937	Missense	proximal	1	no	7.315	14.311	EPSD	COSMIC	10.658	Gain
Atypical_PIKK_ATR_ATR_ST	Q03164	KMT2A	Q13535	ATR	S2943	T2940I	2940	Missense	distal	-3	no	15.749	15.494	EPSD	COSMIC	10.658	Down-regulation
Atypical_PIKK_ATR_ATR_ST	Q03164	KMT2A	Q13535	ATR	S2943	T2940A	2940	Missense	distal	-3	no	15.749	16.310	EPSD	COSMIC	10.658	Up-regulation
Atypical_PIKK_ATR_ATR_ST	Q03164	KMT2A	Q13535	ATR	S2943	P2946S	2946	Missense	distal	3	no	15.749	15.812	EPSD	COSMIC	10.658	Up-regulation
Atypical_PIKK_ATR_ATR_ST	Q03164	KMT2A	Q13535	ATR	S2943	R2937Q	2937	Missense	distal	-6	no	15.749	15.741	EPSD	COSMIC	10.658	Down-regulation
Atypical_PIKK_ATR_ATR_ST	Q03164	KMT2A	Q13535	ATR	S2978	T2984A	2984	Missense	distal	6	no	10.706	10.427	EPSD	COSMIC	10.658	Loss
Atypical_PIKK_ATR_ATR_ST	Q03164	KMT2A	Q13535	ATR	S2978	P2983Q	2983	Missense	distal	5	no	10.706	10.696	EPSD	COSMIC	10.658	Down-regulation
Atypical_PIKK_ATR_ATR_ST	Q03164	KMT2A	Q13535	ATR	S2978	P2983L	2983	Missense	distal	5	no	10.706	10.702	EPSD	COSMIC	10.658	Down-regulation
Atypical_PIKK_ATR_ATR_ST	Q03164	KMT2A	Q13535	ATR	S2978	P2983S	2983	Missense	distal	5	no	10.706	10.695	EPSD	COSMIC	10.658	Down-regulation
Atypical_PIKK_ATR_ATR_ST	Q03164	KMT2A	Q13535	ATR	T3028	S3027G	3027	Missense	proximal	-1	no	11.136	11.230	EPSD	COSMIC	10.658	Up-regulation
Atypical_PIKK_ATR_ATR_ST	Q03164	KMT2A	Q13535	ATR	S3036	P3037Q	3037	Missense	proximal	1	no	10.459	15.326	EPSD	COSMIC	10.658	Gain
Atypical_PIKK_ATR_ATR_ST	Q03164	KMT2A	Q13535	ATR	S3036	P3040A	3040	Missense	distal	4	no	10.459	10.674	EPSD	COSMIC	10.658	Gain
Atypical_PIKK_ATR_ATR_ST	Q03164	KMT2A	Q13535	ATR	S3053	P3048S	3048	Missense	distal	-5	no	11.166	11.136	EPSD	COSMIC	10.658	Down-regulation
Atypical_PIKK_ATR_ATR_ST	Q03164	KMT2A	Q13535	ATR	S3053	P3056L	3056	Missense	distal	3	no	11.166	10.562	EPSD	COSMIC	10.658	Loss
Atypical_PIKK_ATR_ATR_ST	Q03164	KMT2A	Q13535	ATR	S3053	D3052N	3052	Missense	proximal	-1	no	11.166	11.456	EPSD	COSMIC	10.658	Up-regulation
Atypical_PIKK_ATR_ATR_ST	Q03164	KMT2A	Q13535	ATR	S3053	D3052H	3052	Missense	proximal	-1	no	11.166	10.999	EPSD	COSMIC	10.658	Down-regulation
Atypical_PIKK_ATR_ATR_ST	Q03164	KMT2A	Q13535	ATR	S3053	P3056Q	3056	Missense	distal	3	no	11.166	10.799	EPSD	COSMIC	10.658	Down-regulation
Atypical_PIKK_ATR_ATR_ST	Q03164	KMT2A	Q13535	ATR	S3053	V3047M	3047	Missense	distal	-6	no	11.166	11.153	EPSD	COSMIC	10.658	Down-regulation
Atypical_PIKK_ATR_ATR_ST	Q03164	KMT2A	Q13535	ATR	S3057	P3056L	3056	Missense	proximal	-1	no	14.538	14.559	EPSD	COSMIC	10.658	Up-regulation
Atypical_PIKK_ATR_ATR_ST	Q03164	KMT2A	Q13535	ATR	S3057	N3061S	3061	Missense	distal	4	no	14.538	13.900	EPSD	COSMIC	10.658	Down-regulation
Atypical_PIKK_ATR_ATR_ST	Q03164	KMT2A	Q13535	ATR	S3057	D3052N	3052	Missense	distal	-5	no	14.538	14.512	EPSD	COSMIC	10.658	Down-regulation
Atypical_PIKK_ATR_ATR_ST	Q03164	KMT2A	Q13535	ATR	S3057	D3052H	3052	Missense	distal	-5	no	14.538	14.490	EPSD	COSMIC	10.658	Down-regulation
Atypical_PIKK_ATR_ATR_ST	Q03164	KMT2A	Q13535	ATR	S3057	P3056Q	3056	Missense	proximal	-1	no	14.538	14.380	EPSD	COSMIC	10.658	Down-regulation
Atypical_PIKK_ATR_ATR_ST	Q03164	KMT2A	Q13535	ATR	T3213	P3214Q	3214	Missense	proximal	1	no	8.811	13.678	EPSD	COSMIC	10.658	Gain
Atypical_PIKK_ATR_ATR_ST	Q03164	KMT2A	Q13535	ATR	S3503	A3504D	3504	Missense	proximal	1	no	5.983	11.296	EPSD	COSMIC	10.658	Gain
Atypical_PIKK_ATR_ATR_ST	Q03164	KMT2A	Q13535	ATR	S3508	A3507D	3507	Missense	proximal	-1	no	12.226	12.136	EPSD	COSMIC	10.658	Down-regulation
Atypical_PIKK_ATR_ATR_ST	Q03164	KMT2A	Q13535	ATR	S3508	A3504D	3504	Missense	distal	-4	no	12.226	12.537	EPSD	COSMIC	10.658	Up-regulation
Atypical_PIKK_ATR_ATR_ST	Q03164	KMT2A	Q13535	ATR	S3508	P3512L	3512	Missense	distal	4	no	12.226	12.376	EPSD	COSMIC	10.658	Up-regulation
Atypical_PIKK_ATR_ATR_ST	Q03164	KMT2A	Q13535	ATR	S3508	T3510A	3510	Missense	proximal	2	no	12.226	12.764	EPSD	COSMIC;GDSC	10.658	Up-regulation
Atypical_PIKK_ATR_ATR_ST	Q03164	KMT2A	Q13535	ATR	S3508	V3505M	3505	Missense	distal	-3	no	12.226	11.800	EPSD	COSMIC	10.658	Down-regulation
Atypical_PIKK_ATR_ATR_ST	Q03164	KMT2A	Q13535	ATR	S3508	L3501S	3501	Missense	distal	-7	no	12.226	12.391	EPSD	COSMIC	10.658	Up-regulation
Atypical_PIKK_ATR_ATR_ST	Q03164	KMT2A	Q13535	ATR	S3508	S3515F	3515	Missense	distal	7	no	12.226	12.287	EPSD	COSMIC	10.658	Up-regulation
Atypical_PIKK_ATR_ATR_ST	Q03164	KMT2A	Q13535	ATR	S3515	P3512L	3512	Missense	distal	-3	no	11.331	11.626	EPSD	COSMIC	10.658	Up-regulation
Atypical_PIKK_ATR_ATR_ST	Q03164	KMT2A	Q13535	ATR	S3515	P3519S	3519	Missense	distal	4	no	11.331	11.244	EPSD	COSMIC	10.658	Down-regulation
Atypical_PIKK_ATR_ATR_ST	Q03164	KMT2A	Q13535	ATR	S3515	T3510A	3510	Missense	distal	-5	no	11.331	11.414	EPSD	COSMIC;GDSC	10.658	Up-regulation
Atypical_PIKK_ATR_ATR_ST	Q03164	KMT2A	Q13535	ATR	S3515	S3515F	3515	Missense	central	0	yes	11.331	0.000	EPSD	COSMIC	10.658	Loss
Atypical_PIKK_ATR_ATR_ST	Q03164	KMT2A	Q13535	ATR	S3576	S3579L	3579	Missense	distal	3	no	10.872	10.205	EPSD	COSMIC	10.658	Loss
Atypical_PIKK_ATR_ATR_ST	Q03164	KMT2A	Q13535	ATR	S3576	P3570L	3570	Missense	distal	-6	no	10.872	10.936	EPSD	COSMIC	10.658	Up-regulation
Atypical_PIKK_ATR_ATR_ST	Q03164	KMT2A	Q13535	ATR	S3576	L3577P	3577	Missense	proximal	1	no	10.872	11.438	EPSD	COSMIC	10.658	Up-regulation
Atypical_PIKK_ATR_ATR_ST	Q03164	KMT2A	Q13535	ATR	S3576	T3574M	3574	Missense	proximal	-2	no	10.872	10.939	EPSD	COSMIC	10.658	Up-regulation
Atypical_PIKK_ATR_ATR_ST	Q03164	KMT2A	Q13535	ATR	S3576	I3569S	3569	Missense	distal	-7	no	10.872	10.989	EPSD	COSMIC	10.658	Up-regulation
Atypical_PIKK_ATR_ATR_ST	Q03164	KMT2A	Q13535	ATR	S3576	T3581S	3581	Missense	distal	5	no	10.872	10.864	EPSD	COSMIC	10.658	Down-regulation
Atypical_PIKK_ATR_ATR_ST	Q03164	KMT2A	Q13535	ATR	S3576	S3576F	3576	Missense	central	0	yes	10.872	0.000	EPSD	COSMIC	10.658	Loss
Atypical_PIKK_ATR_ATR_ST	Q03164	KMT2A	Q13535	ATR	S3576	I3569V	3569	Missense	distal	-7	no	10.872	10.934	EPSD	COSMIC	10.658	Up-regulation
Atypical_PIKK_ATR_ATR_ST	Q03164	KMT2A	Q13535	ATR	S3576	T3574K	3574	Missense	proximal	-2	no	10.872	10.966	EPSD	COSMIC;GDSC	10.658	Up-regulation
Atypical_PIKK_ATR_ATR_ST	Q03164	KMT2A	Q13535	ATR	S3692	E3687Q	3687	Missense	distal	-5	no	11.579	11.752	EPSD	COSMIC	10.658	Up-regulation
Atypical_PIKK_ATR_ATR_ST	Q03164	KMT2A	Q13535	ATR	S3692	W3690L	3690	Missense	proximal	-2	no	11.579	11.766	EPSD	COSMIC	10.658	Up-regulation
Atypical_PIKK_ATR_ATR_ST	Q03164	KMT2A	Q13535	ATR	S3692	I3686F	3686	Missense	distal	-6	no	11.579	11.575	EPSD	COSMIC	10.658	Down-regulation
Atypical_PIKK_ATR_ATR_ST	Q03164	KMT2A	Q13535	ATR	S3692	D3695E	3695	Missense	distal	3	no	11.579	11.689	EPSD	COSMIC	10.658	Up-regulation
Atypical_PIKK_ATR_ATR_ST	Q03164	KMT2A	Q13535	ATR	S3692	E3687K	3687	Missense	distal	-5	no	11.579	11.660	EPSD	COSMIC	10.658	Up-regulation
Atypical_PIKK_ATR_ATR_ST	Q03164	KMT2A	Q13535	ATR	S3692	E3699Q	3699	Missense	distal	7	no	11.579	11.639	EPSD	COSMIC	10.658	Up-regulation
Atypical_PIKK_ATR_ATR_ST	Q03164	KMT2A	Q13535	ATR	S3702	R3701Q	3701	Missense	proximal	-1	no	12.692	12.622	EPSD	COSMIC	10.658	Down-regulation
Atypical_PIKK_ATR_ATR_ST	Q03164	KMT2A	Q13535	ATR	S3702	N3703I	3703	Missense	proximal	1	no	12.692	9.478	EPSD	COSMIC	10.658	Loss
Atypical_PIKK_ATR_ATR_ST	Q03164	KMT2A	Q13535	ATR	S3702	R3705S	3705	Missense	distal	3	no	12.692	13.128	EPSD	COSMIC	10.658	Up-regulation
Atypical_PIKK_ATR_ATR_ST	Q03164	KMT2A	Q13535	ATR	S3702	D3695E	3695	Missense	distal	-7	no	12.692	12.738	EPSD	COSMIC	10.658	Up-regulation
Atypical_PIKK_ATR_ATR_ST	Q03164	KMT2A	Q13535	ATR	S3702	R3705C	3705	Missense	distal	3	no	12.692	12.825	EPSD	COSMIC	10.658	Up-regulation
Atypical_PIKK_ATR_ATR_ST	Q03164	KMT2A	Q13535	ATR	S3702	E3699Q	3699	Missense	distal	-3	no	12.692	12.845	EPSD	COSMIC	10.658	Up-regulation
Atypical_PIKK_ATR_ATR_ST	Q03164	KMT2A	Q13535	ATR	T3810	R3807W	3807	Missense	distal	-3	no	10.578	10.942	EPSD	COSMIC	10.658	Gain
Atypical_PIKK_ATR_ATR_ST	Q03164	KMT2A	Q13535	ATR	T3810	S3811N	3811	Missense	proximal	1	no	10.578	12.279	EPSD	COSMIC	10.658	Gain
Atypical_PIKK_ATR_ATR_ST	Q02952	AKAP12	Q13535	ATR	S96	A93T	93	Missense	distal	-3	no	14.602	14.041	EPSD	COSMIC	10.658	Down-regulation
Atypical_PIKK_ATR_ATR_ST	Q02952	AKAP12	Q13535	ATR	S96	A93V	93	Missense	distal	-3	no	14.602	14.203	EPSD	COSMIC	10.658	Down-regulation
Atypical_PIKK_ATR_ATR_ST	Q02952	AKAP12	Q13535	ATR	S96	E99K	99	Missense	distal	3	no	14.602	14.759	EPSD	COSMIC	10.658	Up-regulation
Atypical_PIKK_ATR_ATR_ST	Q02952	AKAP12	Q13535	ATR	S96	G90S	90	Missense	distal	-6	no	14.602	14.572	EPSD	COSMIC	10.658	Down-regulation
Atypical_PIKK_ATR_ATR_ST	Q02952	AKAP12	Q13535	ATR	S151	P150S	150	Missense	proximal	-1	no	12.423	12.208	EPSD	COSMIC	10.658	Down-regulation
Atypical_PIKK_ATR_ATR_ST	Q02952	AKAP12	Q13535	ATR	S151	E144K	144	Missense	distal	-7	no	12.423	12.406	EPSD	COSMIC	10.658	Down-regulation
Atypical_PIKK_ATR_ATR_ST	Q02952	AKAP12	Q13535	ATR	S151	P150H	150	Missense	proximal	-1	no	12.423	12.229	EPSD	COSMIC	10.658	Down-regulation
Atypical_PIKK_ATR_ATR_ST	Q02952	AKAP12	Q13535	ATR	S283	P284Q	284	Missense	proximal	1	no	7.465	12.332	EPSD	COSMIC	10.658	Gain
Atypical_PIKK_ATR_ATR_ST	Q02952	AKAP12	Q13535	ATR	T289	P284L	284	Missense	distal	-5	no	11.455	11.608	EPSD	COSMIC	10.658	Up-regulation
Atypical_PIKK_ATR_ATR_ST	Q02952	AKAP12	Q13535	ATR	T289	S283F	283	Missense	distal	-6	no	11.455	11.535	EPSD	COSMIC	10.658	Up-regulation
Atypical_PIKK_ATR_ATR_ST	Q02952	AKAP12	Q13535	ATR	T289	P284Q	284	Missense	distal	-5	no	11.455	11.514	EPSD	COSMIC	10.658	Up-regulation
Atypical_PIKK_ATR_ATR_ST	Q02952	AKAP12	Q13535	ATR	T337	E338Q	338	Missense	proximal	1	no	8.634	14.555	EPSD	COSMIC	10.658	Gain
Atypical_PIKK_ATR_ATR_ST	Q02952	AKAP12	Q13535	ATR	S381	V377A	377	Missense	distal	-4	no	10.236	11.225	EPSD	COSMIC	10.658	Gain
Atypical_PIKK_ATR_ATR_ST	Q02952	AKAP12	Q13535	ATR	S388	G387S	387	Missense	proximal	-1	no	13.618	13.524	EPSD	COSMIC	10.658	Down-regulation
Atypical_PIKK_ATR_ATR_ST	Q02952	AKAP12	Q13535	ATR	S388	G387D	387	Missense	proximal	-1	no	13.618	13.711	EPSD	COSMIC	10.658	Up-regulation
Atypical_PIKK_ATR_ATR_ST	Q02952	AKAP12	Q13535	ATR	S388	K395E	395	Missense	distal	7	no	13.618	13.469	EPSD	COSMIC;GDSC;CCLE	10.658	Down-regulation
Atypical_PIKK_ATR_ATR_ST	Q02952	AKAP12	Q13535	ATR	T401	D405G	405	Missense	distal	4	no	9.913	10.734	EPSD	COSMIC	10.658	Gain
Atypical_PIKK_ATR_ATR_ST	Q02952	AKAP12	Q13535	ATR	S505	R508I	508	Missense	distal	3	no	15.459	15.904	EPSD	COSMIC	10.658	Up-regulation
Atypical_PIKK_ATR_ATR_ST	Q02952	AKAP12	Q13535	ATR	T521	K518T	518	Missense	distal	-3	no	11.065	11.419	EPSD	COSMIC	10.658	Up-regulation
Atypical_PIKK_ATR_ATR_ST	Q02952	AKAP12	Q13535	ATR	T548	P555Q	555	Missense	distal	7	no	12.896	12.754	EPSD	COSMIC	10.658	Down-regulation
Atypical_PIKK_ATR_ATR_ST	Q02952	AKAP12	Q13535	ATR	T548	T548A	548	Missense	central	0	yes	12.896	0.000	EPSD	COSMIC	10.658	Loss
Atypical_PIKK_ATR_ATR_ST	Q02952	AKAP12	Q13535	ATR	T548	D553N	553	Missense	distal	5	no	12.896	12.891	EPSD	COSMIC	10.658	Down-regulation
Atypical_PIKK_ATR_ATR_ST	Q02952	AKAP12	Q13535	ATR	T548	P551Q	551	Missense	distal	3	no	12.896	12.529	EPSD	COSMIC	10.658	Down-regulation
Atypical_PIKK_ATR_ATR_ST	Q02952	AKAP12	Q13535	ATR	T548	E542K	542	Missense	distal	-6	no	12.896	12.848	EPSD	COSMIC	10.658	Down-regulation
Atypical_PIKK_ATR_ATR_ST	Q02952	AKAP12	Q13535	ATR	T548	D541Y	541	Missense	distal	-7	no	12.896	12.738	EPSD	COSMIC	10.658	Down-regulation
Atypical_PIKK_ATR_ATR_ST	Q02952	AKAP12	Q13535	ATR	T548	A552D	552	Missense	distal	4	no	12.896	12.541	EPSD	COSMIC	10.658	Down-regulation
Atypical_PIKK_ATR_ATR_ST	Q02952	AKAP12	Q13535	ATR	S554	P555Q	555	Missense	proximal	1	no	12.675	17.542	EPSD	COSMIC	10.658	Up-regulation
Atypical_PIKK_ATR_ATR_ST	Q02952	AKAP12	Q13535	ATR	S554	T548A	548	Missense	distal	-6	no	12.675	12.697	EPSD	COSMIC	10.658	Up-regulation
Atypical_PIKK_ATR_ATR_ST	Q02952	AKAP12	Q13535	ATR	S554	D553N	553	Missense	proximal	-1	no	12.675	12.965	EPSD	COSMIC	10.658	Up-regulation
Atypical_PIKK_ATR_ATR_ST	Q02952	AKAP12	Q13535	ATR	S554	P551Q	551	Missense	distal	-3	no	12.675	12.751	EPSD	COSMIC	10.658	Up-regulation
Atypical_PIKK_ATR_ATR_ST	Q02952	AKAP12	Q13535	ATR	S554	A552D	552	Missense	proximal	-2	no	12.675	12.292	EPSD	COSMIC	10.658	Down-regulation
Atypical_PIKK_ATR_ATR_ST	Q02952	AKAP12	Q13535	ATR	S557	P555Q	555	Missense	proximal	-2	no	14.036	14.316	EPSD	COSMIC	10.658	Up-regulation
Atypical_PIKK_ATR_ATR_ST	Q02952	AKAP12	Q13535	ATR	S557	D553N	553	Missense	distal	-4	no	14.036	13.427	EPSD	COSMIC	10.658	Down-regulation
Atypical_PIKK_ATR_ATR_ST	Q02952	AKAP12	Q13535	ATR	S557	P551Q	551	Missense	distal	-6	no	14.036	14.065	EPSD	COSMIC	10.658	Up-regulation
Atypical_PIKK_ATR_ATR_ST	Q02952	AKAP12	Q13535	ATR	S557	K562R	562	Missense	distal	5	no	14.036	14.043	EPSD	COSMIC	10.658	Up-regulation
Atypical_PIKK_ATR_ATR_ST	Q02952	AKAP12	Q13535	ATR	S557	A552D	552	Missense	distal	-5	no	14.036	14.108	EPSD	COSMIC	10.658	Up-regulation
Atypical_PIKK_ATR_ATR_ST	Q02952	AKAP12	Q13535	ATR	S688	K689N	689	Missense	proximal	1	no	4.910	11.601	EPSD	COSMIC	10.658	Gain
Atypical_PIKK_ATR_ATR_ST	Q02952	AKAP12	Q13535	ATR	S698	G695R	695	Missense	distal	-3	no	10.781	11.277	EPSD	COSMIC	10.658	Up-regulation
Atypical_PIKK_ATR_ATR_ST	Q02952	AKAP12	Q13535	ATR	S698	D699N	699	Missense	proximal	1	no	10.781	11.920	EPSD	COSMIC	10.658	Up-regulation
Atypical_PIKK_ATR_ATR_ST	Q02952	AKAP12	Q13535	ATR	S698	S698Y	698	Missense	central	0	yes	10.781	0.000	EPSD	COSMIC	10.658	Loss
Atypical_PIKK_ATR_ATR_ST	Q02952	AKAP12	Q13535	ATR	S732	Q733K	733	Missense	proximal	1	no	17.200	6.234	PhosphoSitePlus	COSMIC	10.658	Loss
Atypical_PIKK_ATR_ATR_ST	Q02952	AKAP12	Q13535	ATR	S732	G727A	727	Missense	distal	-5	no	17.200	17.280	PhosphoSitePlus	COSMIC	10.658	Up-regulation
Atypical_PIKK_ATR_ATR_ST	Q02952	AKAP12	Q13535	ATR	S732	G727R	727	Missense	distal	-5	no	17.200	17.366	PhosphoSitePlus	COSMIC	10.658	Up-regulation
Atypical_PIKK_ATR_ATR_ST	Q02952	AKAP12	Q13535	ATR	S741	A747V	747	Missense	distal	6	no	11.220	11.433	EPSD	COSMIC	10.658	Up-regulation
Atypical_PIKK_ATR_ATR_ST	Q02952	AKAP12	Q13535	ATR	T751	G753E	753	Missense	proximal	2	no	10.611	10.741	EPSD	COSMIC	10.658	Gain
Atypical_PIKK_ATR_ATR_ST	Q02952	AKAP12	Q13535	ATR	S887	V889A	889	Missense	proximal	2	no	14.016	13.526	EPSD	COSMIC	10.658	Down-regulation
Atypical_PIKK_ATR_ATR_ST	Q02952	AKAP12	Q13535	ATR	S887	S887C	887	Missense	central	0	yes	14.016	0.000	EPSD	COSMIC	10.658	Loss
Atypical_PIKK_ATR_ATR_ST	Q02952	AKAP12	Q13535	ATR	S887	M891I	891	Missense	distal	4	no	14.016	15.143	EPSD	COSMIC	10.658	Up-regulation
Atypical_PIKK_ATR_ATR_ST	Q02952	AKAP12	Q13535	ATR	T1039	R1038L	1038	Missense	proximal	-1	no	14.575	14.683	EPSD	COSMIC	10.658	Up-regulation
Atypical_PIKK_ATR_ATR_ST	Q02952	AKAP12	Q13535	ATR	T1039	R1038Q	1038	Missense	proximal	-1	no	14.575	14.504	EPSD	COSMIC	10.658	Down-regulation
Atypical_PIKK_ATR_ATR_ST	Q02952	AKAP12	Q13535	ATR	T1039	Q1035E	1035	Missense	distal	-4	no	14.575	15.705	EPSD	COSMIC	10.658	Up-regulation
Atypical_PIKK_ATR_ATR_ST	Q02952	AKAP12	Q13535	ATR	T1039	Q1044K	1044	Missense	distal	5	no	14.575	14.577	EPSD	COSMIC	10.658	Up-regulation
Atypical_PIKK_ATR_ATR_ST	Q02952	AKAP12	Q13535	ATR	T1039	T1039I	1039	Missense	central	0	yes	14.575	0.000	EPSD	COSMIC;GDSC;CCLE	10.658	Loss
Atypical_PIKK_ATR_ATR_ST	Q02952	AKAP12	Q13535	ATR	T1103	E1104Q	1104	Missense	proximal	1	no	5.842	11.762	EPSD	COSMIC	10.658	Gain
Atypical_PIKK_ATR_ATR_ST	Q02952	AKAP12	Q13535	ATR	T1107	E1104Q	1104	Missense	distal	-3	no	14.075	14.228	EPSD	COSMIC	10.658	Up-regulation
Atypical_PIKK_ATR_ATR_ST	Q02952	AKAP12	Q13535	ATR	T1107	G1109W	1109	Missense	proximal	2	no	14.075	12.510	EPSD	COSMIC	10.658	Down-regulation
Atypical_PIKK_ATR_ATR_ST	Q02952	AKAP12	Q13535	ATR	S1149	Q1150H	1150	Missense	proximal	1	no	14.427	-3.091	EPSD	COSMIC	10.658	Loss
Atypical_PIKK_ATR_ATR_ST	Q02952	AKAP12	Q13535	ATR	S1149	V1147M	1147	Missense	proximal	-2	no	14.427	14.540	EPSD	COSMIC	10.658	Up-regulation
Atypical_PIKK_ATR_ATR_ST	Q02952	AKAP12	Q13535	ATR	T1264	L1258M	1258	Missense	distal	-6	no	13.941	13.896	EPSD	COSMIC	10.658	Down-regulation
Atypical_PIKK_ATR_ATR_ST	Q02952	AKAP12	Q13535	ATR	T1264	Y1270H	1270	Missense	distal	6	no	13.941	14.115	EPSD	COSMIC	10.658	Up-regulation
Atypical_PIKK_ATR_ATR_ST	Q02952	AKAP12	Q13535	ATR	T1420	E1416K	1416	Missense	distal	-4	no	10.791	10.380	EPSD	COSMIC	10.658	Loss
Atypical_PIKK_ATR_ATR_ST	Q02952	AKAP12	Q13535	ATR	S1574	M1571L	1571	Missense	distal	-3	no	10.772	11.328	EPSD	COSMIC	10.658	Up-regulation
Atypical_PIKK_ATR_ATR_ST	Q02952	AKAP12	Q13535	ATR	S1574	A1568T	1568	Missense	distal	-6	no	10.772	10.750	EPSD	COSMIC;GDSC;CCLE	10.658	Down-regulation
Atypical_PIKK_ATR_ATR_ST	Q02952	AKAP12	Q13535	ATR	T1578	V1582M	1582	Missense	distal	4	no	12.209	11.602	EPSD	COSMIC	10.658	Down-regulation
Atypical_PIKK_ATR_ATR_ST	Q02952	AKAP12	Q13535	ATR	T1578	M1571L	1571	Missense	distal	-7	no	12.209	12.056	EPSD	COSMIC	10.658	Down-regulation
Atypical_PIKK_ATR_ATR_ST	Q02952	AKAP12	Q13535	ATR	T1578	A1585D	1585	Missense	distal	7	no	12.209	12.296	EPSD	COSMIC	10.658	Up-regulation
Atypical_PIKK_ATR_ATR_ST	Q02952	AKAP12	Q13535	ATR	S1587	V1582M	1582	Missense	distal	-5	no	15.239	15.037	EPSD	COSMIC	10.658	Down-regulation
Atypical_PIKK_ATR_ATR_ST	Q02952	AKAP12	Q13535	ATR	S1587	A1590T	1590	Missense	distal	3	no	15.239	15.551	EPSD	COSMIC	10.658	Up-regulation
Atypical_PIKK_ATR_ATR_ST	Q02952	AKAP12	Q13535	ATR	S1587	T1594M	1594	Missense	distal	7	no	15.239	15.062	EPSD	COSMIC	10.658	Down-regulation
Atypical_PIKK_ATR_ATR_ST	Q02952	AKAP12	Q13535	ATR	S1587	A1585D	1585	Missense	proximal	-2	no	15.239	14.855	EPSD	COSMIC	10.658	Down-regulation
Atypical_PIKK_ATR_ATR_ST	Q02952	AKAP12	Q13535	ATR	S1587	Q1588E	1588	Missense	proximal	1	no	15.239	9.318	EPSD	COSMIC	10.658	Loss
Atypical_PIKK_ATR_ATR_ST	Q02952	AKAP12	Q13535	ATR	S1587	D1586N	1586	Missense	proximal	-1	no	15.239	15.529	EPSD	COSMIC;GDSC;CCLE	10.658	Up-regulation
Atypical_PIKK_ATR_ATR_ST	Q02952	AKAP12	Q13535	ATR	S1587	E1593V	1593	Missense	distal	6	no	15.239	15.041	EPSD	COSMIC	10.658	Down-regulation
Atypical_PIKK_ATR_ATR_ST	Q02952	AKAP12	Q13535	ATR	T1730	Q1735E	1735	Missense	distal	5	no	11.563	11.556	EPSD	COSMIC	10.658	Down-regulation
Atypical_PIKK_ATR_ATR_ST	Q02952	AKAP12	Q13535	ATR	T1730	K1734E	1734	Missense	distal	4	no	11.563	11.452	EPSD	COSMIC	10.658	Down-regulation
Atypical_PIKK_ATR_ATR_ST	Q02952	AKAP12	Q13535	ATR	T1730	P1728L	1728	Missense	proximal	-2	no	11.563	12.214	EPSD	COSMIC	10.658	Up-regulation
Atypical_PIKK_ATR_ATR_ST	Q02952	AKAP12	Q13535	ATR	T1730	P1728R	1728	Missense	proximal	-2	no	11.563	11.921	EPSD	COSMIC	10.658	Up-regulation
Atypical_PIKK_ATR_ATR_ST	Q9Y253	POLH	Q13535	ATR	T408	T401S	401	Missense	distal	-7	no	11.581	11.638	EPSD	COSMIC	10.658	Up-regulation
Atypical_PIKK_ATR_ATR_ST	Q9Y253	POLH	Q13535	ATR	S523	P530L	530	Missense	distal	7	no	14.796	14.795	EPSD	COSMIC	10.658	Down-regulation
Atypical_PIKK_ATR_ATR_ST	Q9Y253	POLH	Q13535	ATR	S523	T522A	522	Missense	proximal	-1	no	14.796	15.026	EPSD	COSMIC;GDSC;CCLE	10.658	Up-regulation
Atypical_PIKK_ATR_ATR_ST	Q9Y253	POLH	Q13535	ATR	S601	H599N	599	Missense	proximal	-2	no	13.889	14.774	PhosphoSitePlus	COSMIC	10.658	Up-regulation
Atypical_PIKK_ATR_ATR_ST	Q9Y253	POLH	Q13535	ATR	T617	P624Q	624	Missense	distal	7	no	13.983	13.842	EPSD	COSMIC	10.658	Down-regulation
Atypical_PIKK_ATR_ATR_ST	Q7Z6Z7	HUWE1	Q13535	ATR	T340	T340A	340	Missense	central	0	yes	11.337	0.000	EPSD	COSMIC	10.658	Loss
Atypical_PIKK_ATR_ATR_ST	Q7Z6Z7	HUWE1	Q13535	ATR	T340	L337F	337	Missense	distal	-3	no	11.337	11.625	EPSD	COSMIC	10.658	Up-regulation
Atypical_PIKK_ATR_ATR_ST	Q7Z6Z7	HUWE1	Q13535	ATR	S525	D521Y	521	Missense	distal	-4	no	11.995	8.768	EPSD	COSMIC	10.658	Loss
Atypical_PIKK_ATR_ATR_ST	Q7Z6Z7	HUWE1	Q13535	ATR	S525	R529Q	529	Missense	distal	4	no	11.995	11.829	EPSD	COSMIC	10.658	Down-regulation
Atypical_PIKK_ATR_ATR_ST	Q7Z6Z7	HUWE1	Q13535	ATR	S636	L634F	634	Missense	proximal	-2	no	11.656	11.552	EPSD	COSMIC	10.658	Down-regulation
Atypical_PIKK_ATR_ATR_ST	Q7Z6Z7	HUWE1	Q13535	ATR	S636	P637L	637	Missense	proximal	1	no	11.656	11.090	EPSD	COSMIC	10.658	Down-regulation
Atypical_PIKK_ATR_ATR_ST	Q7Z6Z7	HUWE1	Q13535	ATR	S718	P716S	716	Missense	proximal	-2	no	11.153	11.102	EPSD	COSMIC	10.658	Down-regulation
Atypical_PIKK_ATR_ATR_ST	Q7Z6Z7	HUWE1	Q13535	ATR	S718	R717M	717	Missense	proximal	-1	no	11.153	11.197	EPSD	COSMIC	10.658	Up-regulation
Atypical_PIKK_ATR_ATR_ST	Q7Z6Z7	HUWE1	Q13535	ATR	S718	A722S	722	Missense	distal	4	no	11.153	10.851	EPSD	COSMIC	10.658	Down-regulation
Atypical_PIKK_ATR_ATR_ST	Q7Z6Z7	HUWE1	Q13535	ATR	S726	S726C	726	Missense	central	0	yes	11.298	0.000	EPSD	COSMIC	10.658	Loss
Atypical_PIKK_ATR_ATR_ST	Q7Z6Z7	HUWE1	Q13535	ATR	S726	A722S	722	Missense	distal	-4	no	11.298	10.777	EPSD	COSMIC	10.658	Down-regulation
Atypical_PIKK_ATR_ATR_ST	Q7Z6Z7	HUWE1	Q13535	ATR	S864	R860H	860	Missense	distal	-4	no	11.829	11.830	EPSD	COSMIC;GDSC;CCLE	10.658	Up-regulation
Atypical_PIKK_ATR_ATR_ST	Q7Z6Z7	HUWE1	Q13535	ATR	S864	H859N	859	Missense	distal	-5	no	11.829	11.851	EPSD	COSMIC	10.658	Up-regulation
Atypical_PIKK_ATR_ATR_ST	Q7Z6Z7	HUWE1	Q13535	ATR	S927	I920V	920	Missense	distal	-7	no	14.559	14.620	EPSD	COSMIC	10.658	Up-regulation
Atypical_PIKK_ATR_ATR_ST	Q7Z6Z7	HUWE1	Q13535	ATR	S1175	M1176V	1176	Missense	proximal	1	no	12.465	-3.144	EPSD	COSMIC;GDSC;CCLE	10.658	Loss
Atypical_PIKK_ATR_ATR_ST	Q7Z6Z7	HUWE1	Q13535	ATR	S1218	S1221T	1221	Missense	distal	3	no	11.806	11.457	EPSD	COSMIC	10.658	Down-regulation
Atypical_PIKK_ATR_ATR_ST	Q7Z6Z7	HUWE1	Q13535	ATR	S1736	L1737M	1737	Missense	proximal	1	no	11.131	12.479	EPSD	COSMIC	10.658	Up-regulation
Atypical_PIKK_ATR_ATR_ST	Q7Z6Z7	HUWE1	Q13535	ATR	T2003	D2002V	2002	Missense	proximal	-1	no	13.917	13.751	EPSD	COSMIC;GDSC;CCLE	10.658	Down-regulation
Atypical_PIKK_ATR_ATR_ST	Q7Z6Z7	HUWE1	Q13535	ATR	S2011	A2016T	2016	Missense	distal	5	no	13.088	13.085	EPSD	COSMIC	10.658	Down-regulation
Atypical_PIKK_ATR_ATR_ST	Q7Z6Z7	HUWE1	Q13535	ATR	S2011	G2018V	2018	Missense	distal	7	no	13.088	13.332	EPSD	COSMIC	10.658	Up-regulation
Atypical_PIKK_ATR_ATR_ST	Q7Z6Z7	HUWE1	Q13535	ATR	S2011	G2018W	2018	Missense	distal	7	no	13.088	13.404	EPSD	COSMIC	10.658	Up-regulation
Atypical_PIKK_ATR_ATR_ST	Q7Z6Z7	HUWE1	Q13535	ATR	S2339	E2341K	2341	Missense	proximal	2	no	15.536	14.587	EPSD	COSMIC	10.658	Down-regulation
Atypical_PIKK_ATR_ATR_ST	Q7Z6Z7	HUWE1	Q13535	ATR	S2377	E2376K	2376	Missense	proximal	-1	no	14.088	13.839	EPSD	COSMIC	10.658	Down-regulation
Atypical_PIKK_ATR_ATR_ST	Q7Z6Z7	HUWE1	Q13535	ATR	S2391	A2398T	2398	Missense	distal	7	no	16.807	16.908	PhosphoSitePlus	COSMIC	10.658	Up-regulation
Atypical_PIKK_ATR_ATR_ST	Q7Z6Z7	HUWE1	Q13535	ATR	S2391	Q2392K	2392	Missense	proximal	1	no	16.807	5.840	PhosphoSitePlus	COSMIC	10.658	Loss
Atypical_PIKK_ATR_ATR_ST	Q7Z6Z7	HUWE1	Q13535	ATR	S2508	P2506S	2506	Missense	proximal	-2	no	11.458	11.406	EPSD	COSMIC	10.658	Down-regulation
Atypical_PIKK_ATR_ATR_ST	Q7Z6Z7	HUWE1	Q13535	ATR	T2540	R2538L	2538	Missense	proximal	-2	no	14.630	14.924	EPSD	COSMIC	10.658	Up-regulation
Atypical_PIKK_ATR_ATR_ST	Q7Z6Z7	HUWE1	Q13535	ATR	T2540	G2544R	2544	Missense	distal	4	no	14.630	13.914	EPSD	COSMIC;GDSC;CCLE	10.658	Down-regulation
Atypical_PIKK_ATR_ATR_ST	Q7Z6Z7	HUWE1	Q13535	ATR	T2540	L2539H	2539	Missense	proximal	-1	no	14.630	14.416	EPSD	COSMIC	10.658	Down-regulation
Atypical_PIKK_ATR_ATR_ST	Q7Z6Z7	HUWE1	Q13535	ATR	T2540	T2540P	2540	Missense	central	0	yes	14.630	0.000	EPSD	COSMIC	10.658	Loss
Atypical_PIKK_ATR_ATR_ST	Q7Z6Z7	HUWE1	Q13535	ATR	S2546	G2544R	2544	Missense	proximal	-2	no	12.203	12.299	EPSD	COSMIC;GDSC;CCLE	10.658	Up-regulation
Atypical_PIKK_ATR_ATR_ST	Q7Z6Z7	HUWE1	Q13535	ATR	S2546	L2539H	2539	Missense	distal	-7	no	12.203	12.373	EPSD	COSMIC	10.658	Up-regulation
Atypical_PIKK_ATR_ATR_ST	Q7Z6Z7	HUWE1	Q13535	ATR	S2546	T2540P	2540	Missense	distal	-6	no	12.203	12.163	EPSD	COSMIC	10.658	Down-regulation
Atypical_PIKK_ATR_ATR_ST	Q7Z6Z7	HUWE1	Q13535	ATR	T2821	L2825R	2825	Missense	distal	4	no	15.256	15.071	EPSD	COSMIC	10.658	Down-regulation
Atypical_PIKK_ATR_ATR_ST	Q7Z6Z7	HUWE1	Q13535	ATR	T2821	P2827Q	2827	Missense	distal	6	no	15.256	15.425	EPSD	COSMIC	10.658	Up-regulation
Atypical_PIKK_ATR_ATR_ST	Q7Z6Z7	HUWE1	Q13535	ATR	T2821	S2826F	2826	Missense	distal	5	no	15.256	15.268	EPSD	COSMIC	10.658	Up-regulation
Atypical_PIKK_ATR_ATR_ST	Q7Z6Z7	HUWE1	Q13535	ATR	T2821	S2815N	2815	Missense	distal	-6	no	15.256	15.322	EPSD	COSMIC	10.658	Up-regulation
Atypical_PIKK_ATR_ATR_ST	Q7Z6Z7	HUWE1	Q13535	ATR	S2826	P2827Q	2827	Missense	proximal	1	no	10.030	14.898	EPSD	COSMIC	10.658	Gain
Atypical_PIKK_ATR_ATR_ST	Q7Z6Z7	HUWE1	Q13535	ATR	S2835	P2836Q	2836	Missense	proximal	1	no	8.501	13.368	EPSD	COSMIC	10.658	Gain
Atypical_PIKK_ATR_ATR_ST	Q7Z6Z7	HUWE1	Q13535	ATR	S2850	A2844S	2844	Missense	distal	-6	no	13.939	13.832	EPSD	COSMIC	10.658	Down-regulation
Atypical_PIKK_ATR_ATR_ST	Q7Z6Z7	HUWE1	Q13535	ATR	S2850	V2848A	2848	Missense	proximal	-2	no	13.939	14.459	EPSD	COSMIC	10.658	Up-regulation
Atypical_PIKK_ATR_ATR_ST	Q7Z6Z7	HUWE1	Q13535	ATR	S2904	V2900M	2900	Missense	distal	-4	no	10.709	10.957	EPSD	COSMIC	10.658	Up-regulation
Atypical_PIKK_ATR_ATR_ST	Q7Z6Z7	HUWE1	Q13535	ATR	S2922	S2918F	2918	Missense	distal	-4	no	10.847	10.563	EPSD	COSMIC	10.658	Loss
Atypical_PIKK_ATR_ATR_ST	Q7Z6Z7	HUWE1	Q13535	ATR	S2922	R2929T	2929	Missense	distal	7	no	10.847	10.795	EPSD	COSMIC	10.658	Down-regulation
Atypical_PIKK_ATR_ATR_ST	Q7Z6Z7	HUWE1	Q13535	ATR	S2940	V2933L	2933	Missense	distal	-7	no	11.278	11.168	EPSD	COSMIC	10.658	Down-regulation
Atypical_PIKK_ATR_ATR_ST	Q7Z6Z7	HUWE1	Q13535	ATR	S2953	P2949L	2949	Missense	distal	-4	no	12.169	10.969	EPSD	COSMIC	10.658	Down-regulation
Atypical_PIKK_ATR_ATR_ST	Q7Z6Z7	HUWE1	Q13535	ATR	S3560	S3565F	3565	Missense	distal	5	no	10.937	10.949	EPSD	COSMIC	10.658	Up-regulation
Atypical_PIKK_ATR_ATR_ST	Q7Z6Z7	HUWE1	Q13535	ATR	S3695	V3691A	3691	Missense	distal	-4	no	13.817	14.806	EPSD	COSMIC	10.658	Up-regulation
Atypical_PIKK_ATR_ATR_ST	Q7Z6Z7	HUWE1	Q13535	ATR	S3797	A3792V	3792	Missense	distal	-5	no	13.897	13.899	EPSD	COSMIC	10.658	Up-regulation
Atypical_PIKK_ATR_ATR_ST	Q7Z6Z7	HUWE1	Q13535	ATR	S3797	E3795K	3795	Missense	proximal	-2	no	13.897	13.996	EPSD	COSMIC	10.658	Up-regulation
Atypical_PIKK_ATR_ATR_ST	Q7Z6Z7	HUWE1	Q13535	ATR	S3797	R3804W	3804	Missense	distal	7	no	13.897	13.956	EPSD	COSMIC	10.658	Up-regulation
Atypical_PIKK_ATR_ATR_ST	Q7Z6Z7	HUWE1	Q13535	ATR	T3822	Q3823H	3823	Missense	proximal	1	no	13.748	-3.770	EPSD	COSMIC	10.658	Loss
Atypical_PIKK_ATR_ATR_ST	Q7Z6Z7	HUWE1	Q13535	ATR	S3906	E3905K	3905	Missense	proximal	-1	no	11.695	11.446	EPSD	COSMIC	10.658	Down-regulation
Atypical_PIKK_ATR_ATR_ST	Q7Z6Z7	HUWE1	Q13535	ATR	S3906	V3900A	3900	Missense	distal	-6	no	11.695	11.725	EPSD	COSMIC	10.658	Up-regulation
Atypical_PIKK_ATR_ATR_ST	Q7Z6Z7	HUWE1	Q13535	ATR	S3906	K3912R	3912	Missense	distal	6	no	11.695	11.413	EPSD	COSMIC	10.658	Down-regulation
Atypical_PIKK_ATR_ATR_ST	Q7Z6Z7	HUWE1	Q13535	ATR	T4083	T4083A	4083	Missense	central	0	yes	11.409	0.000	EPSD	COSMIC	10.658	Loss
Atypical_PIKK_ATR_ATR_ST	Q7Z6Z7	HUWE1	Q13535	ATR	T4083	D4087N	4087	Missense	distal	4	no	11.409	12.099	EPSD	COSMIC	10.658	Up-regulation
Atypical_PIKK_ATR_ATR_ST	Q9NZN8	CNOT2	Q13535	ATR	S143	Q144H	144	Missense	proximal	1	no	12.536	-4.982	EPSD	COSMIC;GDSC;CCLE	10.658	Loss
Atypical_PIKK_ATR_ATR_ST	Q9NZN8	CNOT2	Q13535	ATR	S165	G162E	162	Missense	distal	-3	no	10.527	10.686	EPSD	COSMIC	10.658	Gain
Atypical_PIKK_ATR_ATR_ST	Q9NZN8	CNOT2	Q13535	ATR	S190	M196I	196	Missense	distal	6	no	12.653	12.720	EPSD	COSMIC	10.658	Up-regulation
Atypical_PIKK_ATR_ATR_ST	Q9NZN8	CNOT2	Q13535	ATR	S190	N189S	189	Missense	proximal	-1	no	12.653	12.176	EPSD	COSMIC;GDSC;CCLE	10.658	Down-regulation
Atypical_PIKK_ATR_ATR_ST	Q9NZN8	CNOT2	Q13535	ATR	S270	Q269R	269	Missense	proximal	-1	no	13.291	13.361	EPSD	COSMIC	10.658	Up-regulation
Atypical_PIKK_ATR_ATR_ST	Q9NZN8	CNOT2	Q13535	ATR	S305	S298T	298	Missense	distal	-7	no	10.856	10.798	EPSD	COSMIC;GDSC;CCLE	10.658	Down-regulation
Atypical_PIKK_ATR_ATR_ST	Q9NZN8	CNOT2	Q13535	ATR	S391	L395F	395	Missense	distal	4	no	12.436	12.217	EPSD	COSMIC	10.658	Down-regulation
Atypical_PIKK_ATR_ATR_ST	Q9NZN8	CNOT2	Q13535	ATR	S391	S391F	391	Missense	central	0	yes	12.436	0.000	EPSD	COSMIC	10.658	Loss
Atypical_PIKK_ATR_ATR_ST	Q9NZN8	CNOT2	Q13535	ATR	S391	T384A	384	Missense	distal	-7	no	12.436	12.459	EPSD	COSMIC	10.658	Up-regulation
Atypical_PIKK_ATR_ATR_ST	Q9UH99	SUN2	Q13535	ATR	S5	S12F	12	Missense	distal	7	no	14.154	14.216	EPSD	COSMIC	10.658	Up-regulation
Atypical_PIKK_ATR_ATR_ST	Q9UH99	SUN2	Q13535	ATR	S12	S12F	12	Missense	central	0	yes	14.831	0.000	PhosphoSitePlus	COSMIC	10.658	Loss
Atypical_PIKK_ATR_ATR_ST	Q9UH99	SUN2	Q13535	ATR	S12	D15Y	15	Missense	distal	3	no	14.831	14.338	PhosphoSitePlus	COSMIC	10.658	Down-regulation
Atypical_PIKK_ATR_ATR_ST	Q9UH99	SUN2	Q13535	ATR	S19	S12F	12	Missense	distal	-7	no	11.333	11.225	EPSD	COSMIC	10.658	Down-regulation
Atypical_PIKK_ATR_ATR_ST	Q9UH99	SUN2	Q13535	ATR	S19	D15Y	15	Missense	distal	-4	no	11.333	8.106	EPSD	COSMIC	10.658	Loss
Atypical_PIKK_ATR_ATR_ST	Q9UH99	SUN2	Q13535	ATR	S85	D92N	92	Missense	distal	7	no	10.863	11.087	EPSD	COSMIC	10.658	Up-regulation
Atypical_PIKK_ATR_ATR_ST	Q9UH99	SUN2	Q13535	ATR	S160	G163D	163	Missense	distal	3	no	11.790	11.859	EPSD	COSMIC	10.658	Up-regulation
Atypical_PIKK_ATR_ATR_ST	Q9UH99	SUN2	Q13535	ATR	S160	R161Q	161	Missense	proximal	1	no	11.790	18.786	EPSD	COSMIC;GDSC;CCLE	10.658	Up-regulation
Atypical_PIKK_ATR_ATR_ST	Q9UH99	SUN2	Q13535	ATR	S282	E284K	284	Missense	proximal	2	no	10.712	9.763	EPSD	COSMIC	10.658	Loss
Atypical_PIKK_ATR_ATR_ST	Q9UH99	SUN2	Q13535	ATR	S282	S278F	278	Missense	distal	-4	no	10.712	10.429	EPSD	COSMIC	10.658	Loss
Atypical_PIKK_ATR_ATR_ST	Q9UH99	SUN2	Q13535	ATR	S282	R275H	275	Missense	distal	-7	no	10.712	10.764	EPSD	COSMIC	10.658	Up-regulation
Atypical_PIKK_ATR_ATR_ST	Q9UH99	SUN2	Q13535	ATR	S381	R387S	387	Missense	distal	6	no	13.945	14.342	EPSD	COSMIC	10.658	Up-regulation
Atypical_PIKK_ATR_ATR_ST	Q9BUG6	ZSCAN5A	Q13535	ATR	T236	R229M	229	Missense	distal	-7	no	12.241	12.276	EPSD	COSMIC	10.658	Up-regulation
Atypical_PIKK_ATR_ATR_ST	Q9BUG6	ZSCAN5A	Q13535	ATR	T236	P233S	233	Missense	distal	-3	no	12.241	11.964	EPSD	COSMIC	10.658	Down-regulation
Atypical_PIKK_ATR_ATR_ST	Q9BUG6	ZSCAN5A	Q13535	ATR	T236	G234C	234	Missense	proximal	-2	no	12.241	12.567	EPSD	COSMIC	10.658	Up-regulation
Atypical_PIKK_ATR_ATR_ST	Q9BUG6	ZSCAN5A	Q13535	ATR	T236	L242I	242	Missense	distal	6	no	12.241	12.192	EPSD	COSMIC	10.658	Down-regulation
Atypical_PIKK_ATR_ATR_ST	Q9BUG6	ZSCAN5A	Q13535	ATR	S285	G286W	286	Missense	proximal	1	no	8.865	10.887	EPSD	COSMIC	10.658	Gain
Atypical_PIKK_ATR_ATR_ST	Q9BUG6	ZSCAN5A	Q13535	ATR	S296	G289A	289	Missense	distal	-7	no	11.659	11.672	EPSD	COSMIC	10.658	Up-regulation
Atypical_PIKK_ATR_ATR_ST	Q9BUG6	ZSCAN5A	Q13535	ATR	S296	S296G	296	Missense	central	0	yes	11.659	0.000	EPSD	COSMIC	10.658	Loss
Atypical_PIKK_ATR_ATR_ST	Q9BUG6	ZSCAN5A	Q13535	ATR	S296	S295R	295	Missense	proximal	-1	no	11.659	11.786	EPSD	COSMIC	10.658	Up-regulation
Atypical_PIKK_ATR_ATR_ST	Q9BUG6	ZSCAN5A	Q13535	ATR	S296	S295G	295	Missense	proximal	-1	no	11.659	11.752	EPSD	COSMIC	10.658	Up-regulation
Atypical_PIKK_ATR_ATR_ST	Q9BUG6	ZSCAN5A	Q13535	ATR	S308	S306F	306	Missense	proximal	-2	no	12.844	13.442	EPSD	COSMIC	10.658	Up-regulation
Atypical_PIKK_ATR_ATR_ST	Q9BUG6	ZSCAN5A	Q13535	ATR	S308	E311K	311	Missense	distal	3	no	12.844	13.001	EPSD	COSMIC	10.658	Up-regulation
Atypical_PIKK_ATR_ATR_ST	Q9BUG6	ZSCAN5A	Q13535	ATR	S308	E311D	311	Missense	distal	3	no	12.844	12.734	EPSD	COSMIC	10.658	Down-regulation
Atypical_PIKK_ATR_ATR_ST	Q9BUG6	ZSCAN5A	Q13535	ATR	S308	E310K	310	Missense	proximal	2	no	12.844	11.895	EPSD	COSMIC	10.658	Down-regulation
Atypical_PIKK_ATR_ATR_ST	Q9BUG6	ZSCAN5A	Q13535	ATR	S308	E310D	310	Missense	proximal	2	no	12.844	11.168	EPSD	COSMIC	10.658	Down-regulation
Atypical_PIKK_ATR_ATR_ST	Q9BUG6	ZSCAN5A	Q13535	ATR	S308	E310G	310	Missense	proximal	2	no	12.844	12.714	EPSD	COSMIC	10.658	Down-regulation
Atypical_PIKK_ATR_ATR_ST	Q9BUG6	ZSCAN5A	Q13535	ATR	S324	Q327H	327	Missense	distal	3	no	10.310	10.713	EPSD	COSMIC	10.658	Gain
Atypical_PIKK_ATR_ATR_ST	Q9BUG6	ZSCAN5A	Q13535	ATR	S335	S332R	332	Missense	distal	-3	no	10.254	10.791	EPSD	COSMIC	10.658	Gain
Atypical_PIKK_ATR_ATR_ST	Q9BUG6	ZSCAN5A	Q13535	ATR	T422	Q420R	420	Missense	proximal	-2	no	16.118	16.196	PhosphoSitePlus	COSMIC	10.658	Up-regulation
Atypical_PIKK_ATR_ATR_ST	Q9BUG6	ZSCAN5A	Q13535	ATR	T422	C429R	429	Missense	distal	7	no	16.118	15.979	PhosphoSitePlus	COSMIC	10.658	Down-regulation
Atypical_PIKK_ATR_ATR_ST	Q8IZL8	PELP1	Q13535	ATR	S251	A248T	248	Missense	distal	-3	no	12.188	11.626	EPSD	COSMIC	10.658	Down-regulation
Atypical_PIKK_ATR_ATR_ST	Q8IZL8	PELP1	Q13535	ATR	S477	P478Q	478	Missense	proximal	1	no	8.702	13.569	EPSD	COSMIC	10.658	Gain
Atypical_PIKK_ATR_ATR_ST	Q8IZL8	PELP1	Q13535	ATR	S658	F660S	660	Missense	proximal	2	no	8.457	11.145	EPSD	COSMIC	10.658	Gain
Atypical_PIKK_ATR_ATR_ST	Q8IZL8	PELP1	Q13535	ATR	S734	P727S	727	Missense	distal	-7	no	11.506	11.478	EPSD	COSMIC	10.658	Down-regulation
Atypical_PIKK_ATR_ATR_ST	Q8IZL8	PELP1	Q13535	ATR	S734	L740F	740	Missense	distal	6	no	11.506	11.572	EPSD	COSMIC	10.658	Up-regulation
Atypical_PIKK_ATR_ATR_ST	Q8IZL8	PELP1	Q13535	ATR	S734	I739T	739	Missense	distal	5	no	11.506	11.502	EPSD	COSMIC	10.658	Down-regulation
Atypical_PIKK_ATR_ATR_ST	Q8IZL8	PELP1	Q13535	ATR	T807	P808Q	808	Missense	proximal	1	no	8.398	13.265	EPSD	COSMIC	10.658	Gain
Atypical_PIKK_ATR_ATR_ST	Q8IZL8	PELP1	Q13535	ATR	S991	A985P	985	Missense	distal	-6	no	11.673	11.610	EPSD	COSMIC	10.658	Down-regulation
Atypical_PIKK_ATR_ATR_ST	Q8IZL8	PELP1	Q13535	ATR	S991	A985T	985	Missense	distal	-6	no	11.673	11.651	EPSD	COSMIC	10.658	Down-regulation
Atypical_PIKK_ATR_ATR_ST	Q8IZL8	PELP1	Q13535	ATR	S991	E998Q	998	Missense	distal	7	no	11.673	11.733	EPSD	COSMIC	10.658	Up-regulation
Atypical_PIKK_ATR_ATR_ST	Q8IZL8	PELP1	Q13535	ATR	S1033	S1033C	1033	Missense	central	0	yes	16.039	0.000	PhosphoSitePlus	COSMIC	10.658	Loss
Atypical_PIKK_ATR_ATR_ST	Q8IZL8	PELP1	Q13535	ATR	S1033	S1033F	1033	Missense	central	0	yes	16.039	0.000	PhosphoSitePlus	COSMIC	10.658	Loss
Atypical_PIKK_ATR_ATR_ST	Q8IZL8	PELP1	Q13535	ATR	S1033	P1028L	1028	Missense	distal	-5	no	16.039	16.192	PhosphoSitePlus	COSMIC	10.658	Up-regulation
Atypical_PIKK_ATR_ATR_ST	Q8IZL8	PELP1	Q13535	ATR	S1033	E1036K	1036	Missense	distal	3	no	16.039	16.196	PhosphoSitePlus	COSMIC	10.658	Up-regulation
Atypical_PIKK_ATR_ATR_ST	Q8IZL8	PELP1	Q13535	ATR	S1033	E1040V	1040	Missense	distal	7	no	16.039	16.287	PhosphoSitePlus	COSMIC	10.658	Up-regulation
Atypical_PIKK_ATR_ATR_ST	Q8IZL8	PELP1	Q13535	ATR	S1073	P1078L	1078	Missense	distal	5	no	11.590	11.585	EPSD	COSMIC	10.658	Down-regulation
Atypical_PIKK_ATR_ATR_ST	O94880	PHF14	Q13535	ATR	S26	D24A	24	Missense	proximal	-2	no	11.539	11.922	EPSD	COSMIC	10.658	Up-regulation
Atypical_PIKK_ATR_ATR_ST	O94880	PHF14	Q13535	ATR	S26	S25T	25	Missense	proximal	-1	no	11.539	11.585	EPSD	COSMIC	10.658	Up-regulation
Atypical_PIKK_ATR_ATR_ST	O94880	PHF14	Q13535	ATR	S26	D28N	28	Missense	proximal	2	no	11.539	12.459	EPSD	COSMIC	10.658	Up-regulation
Atypical_PIKK_ATR_ATR_ST	O94880	PHF14	Q13535	ATR	S39	D38H	38	Missense	proximal	-1	no	10.900	10.733	EPSD	COSMIC	10.658	Down-regulation
Atypical_PIKK_ATR_ATR_ST	O94880	PHF14	Q13535	ATR	S39	G43V	43	Missense	distal	4	no	10.900	10.293	EPSD	COSMIC	10.658	Loss
Atypical_PIKK_ATR_ATR_ST	O94880	PHF14	Q13535	ATR	T162	T155P	155	Missense	distal	-7	no	11.150	11.235	EPSD	COSMIC	10.658	Up-regulation
Atypical_PIKK_ATR_ATR_ST	O94880	PHF14	Q13535	ATR	T162	T168S	168	Missense	distal	6	no	11.150	11.197	EPSD	COSMIC	10.658	Up-regulation
Atypical_PIKK_ATR_ATR_ST	O94880	PHF14	Q13535	ATR	S163	T168S	168	Missense	distal	5	no	11.998	11.990	EPSD	COSMIC	10.658	Down-regulation
Atypical_PIKK_ATR_ATR_ST	O94880	PHF14	Q13535	ATR	T287	A281T	281	Missense	distal	-6	no	11.825	11.804	EPSD	COSMIC	10.658	Down-regulation
Atypical_PIKK_ATR_ATR_ST	O94880	PHF14	Q13535	ATR	S530	I537M	537	Missense	distal	7	no	12.401	12.075	EPSD	COSMIC	10.658	Down-regulation
Atypical_PIKK_ATR_ATR_ST	O94880	PHF14	Q13535	ATR	S530	A535G	535	Missense	distal	5	no	12.401	12.395	EPSD	COSMIC	10.658	Down-regulation
Atypical_PIKK_ATR_ATR_ST	O94880	PHF14	Q13535	ATR	S601	D599V	599	Missense	proximal	-2	no	12.380	12.244	EPSD	COSMIC	10.658	Down-regulation
Atypical_PIKK_ATR_ATR_ST	O94880	PHF14	Q13535	ATR	S601	G606E	606	Missense	distal	5	no	12.380	12.370	EPSD	COSMIC	10.658	Down-regulation
Atypical_PIKK_ATR_ATR_ST	O94880	PHF14	Q13535	ATR	S664	L665S	665	Missense	proximal	1	no	14.442	13.899	EPSD	COSMIC	10.658	Down-regulation
Atypical_PIKK_ATR_ATR_ST	O94880	PHF14	Q13535	ATR	T715	G713R	713	Missense	proximal	-2	no	12.952	13.048	EPSD	COSMIC;GDSC;CCLE	10.658	Up-regulation
Atypical_PIKK_ATR_ATR_ST	Q8N4S0	CCDC82	Q13535	ATR	S131	D136Y	136	Missense	distal	5	no	13.651	13.663	EPSD	COSMIC	10.658	Up-regulation
Atypical_PIKK_ATR_ATR_ST	Q8N4S0	CCDC82	Q13535	ATR	S131	N135T	135	Missense	distal	4	no	13.651	13.064	EPSD	COSMIC	10.658	Down-regulation
Atypical_PIKK_ATR_ATR_ST	Q8N4S0	CCDC82	Q13535	ATR	S131	S131R	131	Missense	central	0	yes	13.651	0.000	EPSD	COSMIC	10.658	Loss
Atypical_PIKK_ATR_ATR_ST	Q8N4S0	CCDC82	Q13535	ATR	S131	D136A	136	Missense	distal	5	no	13.651	13.652	EPSD	COSMIC	10.658	Up-regulation
Atypical_PIKK_ATR_ATR_ST	Q8N4S0	CCDC82	Q13535	ATR	S154	S154R	154	Missense	central	0	yes	16.298	0.000	PhosphoSitePlus	COSMIC	10.658	Loss
Atypical_PIKK_ATR_ATR_ST	Q8N4S0	CCDC82	Q13535	ATR	S320	E315K	315	Missense	distal	-5	no	13.838	13.919	EPSD	COSMIC	10.658	Up-regulation
Atypical_PIKK_ATR_ATR_ST	Q8N4S0	CCDC82	Q13535	ATR	S320	L324V	324	Missense	distal	4	no	13.838	13.764	EPSD	COSMIC	10.658	Down-regulation
Atypical_PIKK_ATR_ATR_ST	Q8N4S0	CCDC82	Q13535	ATR	S391	R395I	395	Missense	distal	4	no	10.192	10.822	EPSD	COSMIC;GDSC;CCLE	10.658	Gain
Atypical_PIKK_ATR_ATR_ST	Q01844	EWSR1	Q13535	ATR	S274	F267I	267	Missense	distal	-7	no	13.008	12.999	EPSD	COSMIC	10.658	Down-regulation
Atypical_PIKK_ATR_ATR_ST	Q01844	EWSR1	Q13535	ATR	S274	R268L	268	Missense	distal	-6	no	13.008	13.036	EPSD	COSMIC	10.658	Up-regulation
Atypical_PIKK_ATR_ATR_ST	Q01844	EWSR1	Q13535	ATR	S274	Q269H	269	Missense	distal	-5	no	13.008	13.040	EPSD	COSMIC	10.658	Up-regulation
Atypical_PIKK_ATR_ATR_ST	Q01844	EWSR1	Q13535	ATR	S274	G279R	279	Missense	distal	5	no	13.008	13.014	EPSD	COSMIC	10.658	Up-regulation
Atypical_PIKK_ATR_ATR_ST	Q01844	EWSR1	Q13535	ATR	S274	M275I	275	Missense	proximal	1	no	13.008	9.604	EPSD	COSMIC	10.658	Loss
Atypical_PIKK_ATR_ATR_ST	Q01844	EWSR1	Q13535	ATR	S358	D355Y	355	Missense	distal	-3	no	11.651	11.694	EPSD	COSMIC	10.658	Up-regulation
Atypical_PIKK_ATR_ATR_ST	Q01844	EWSR1	Q13535	ATR	S358	P351S	351	Missense	distal	-7	no	11.651	11.623	EPSD	COSMIC	10.658	Down-regulation
Atypical_PIKK_ATR_ATR_ST	Q01844	EWSR1	Q13535	ATR	S358	D359N	359	Missense	proximal	1	no	11.651	12.789	EPSD	COSMIC	10.658	Up-regulation
Atypical_PIKK_ATR_ATR_ST	Q14676	MDC1	Q13535	ATR	T17	E18Q	18	Missense	proximal	1	no	8.106	14.027	EPSD	COSMIC	10.658	Gain
Atypical_PIKK_ATR_ATR_ST	Q14676	MDC1	Q13535	ATR	S20	E18Q	18	Missense	proximal	-2	no	10.976	11.011	EPSD	COSMIC	10.658	Up-regulation
Atypical_PIKK_ATR_ATR_ST	Q14676	MDC1	Q13535	ATR	S23	E18Q	18	Missense	distal	-5	no	11.770	11.943	EPSD	COSMIC	10.658	Up-regulation
Atypical_PIKK_ATR_ATR_ST	Q14676	MDC1	Q13535	ATR	S108	P103L	103	Missense	distal	-5	no	10.591	10.744	EPSD	COSMIC	10.658	Gain
Atypical_PIKK_ATR_ATR_ST	Q14676	MDC1	Q13535	ATR	S202	G200E	200	Missense	proximal	-2	no	11.539	11.522	EPSD	COSMIC	10.658	Down-regulation
Atypical_PIKK_ATR_ATR_ST	Q14676	MDC1	Q13535	ATR	S218	L216F	216	Missense	proximal	-2	no	13.752	13.647	EPSD	COSMIC	10.658	Down-regulation
Atypical_PIKK_ATR_ATR_ST	Q14676	MDC1	Q13535	ATR	S218	D221N	221	Missense	distal	3	no	13.752	13.921	EPSD	COSMIC	10.658	Up-regulation
Atypical_PIKK_ATR_ATR_ST	Q14676	MDC1	Q13535	ATR	S218	E224K	224	Missense	distal	6	no	13.752	13.552	EPSD	COSMIC	10.658	Down-regulation
Atypical_PIKK_ATR_ATR_ST	Q14676	MDC1	Q13535	ATR	S292	L289V	289	Missense	distal	-3	no	14.708	14.577	EPSD	COSMIC	10.658	Down-regulation
Atypical_PIKK_ATR_ATR_ST	Q14676	MDC1	Q13535	ATR	S292	P295S	295	Missense	distal	3	no	14.708	14.772	EPSD	COSMIC	10.658	Up-regulation
Atypical_PIKK_ATR_ATR_ST	Q14676	MDC1	Q13535	ATR	S292	P295L	295	Missense	distal	3	no	14.708	14.105	EPSD	COSMIC	10.658	Down-regulation
Atypical_PIKK_ATR_ATR_ST	Q14676	MDC1	Q13535	ATR	T301	R308M	308	Missense	distal	7	no	13.462	13.233	EPSD	COSMIC;GDSC;CCLE	10.658	Down-regulation
Atypical_PIKK_ATR_ATR_ST	Q14676	MDC1	Q13535	ATR	T301	P295S	295	Missense	distal	-6	no	13.462	13.416	EPSD	COSMIC	10.658	Down-regulation
Atypical_PIKK_ATR_ATR_ST	Q14676	MDC1	Q13535	ATR	T301	V303L	303	Missense	proximal	2	no	13.462	11.859	EPSD	COSMIC	10.658	Down-regulation
Atypical_PIKK_ATR_ATR_ST	Q14676	MDC1	Q13535	ATR	T301	P295L	295	Missense	distal	-6	no	13.462	13.526	EPSD	COSMIC	10.658	Up-regulation
Atypical_PIKK_ATR_ATR_ST	Q14676	MDC1	Q13535	ATR	S307	R308M	308	Missense	proximal	1	no	7.966	10.876	EPSD	COSMIC;GDSC;CCLE	10.658	Gain
Atypical_PIKK_ATR_ATR_ST	Q14676	MDC1	Q13535	ATR	S329	Q322E	322	Missense	distal	-7	no	11.485	11.530	EPSD	COSMIC	10.658	Up-regulation
Atypical_PIKK_ATR_ATR_ST	Q14676	MDC1	Q13535	ATR	S329	A333V	333	Missense	distal	4	no	11.485	11.346	EPSD	COSMIC	10.658	Down-regulation
Atypical_PIKK_ATR_ATR_ST	Q14676	MDC1	Q13535	ATR	S329	G325A	325	Missense	distal	-4	no	11.485	12.523	EPSD	COSMIC	10.658	Up-regulation
Atypical_PIKK_ATR_ATR_ST	Q14676	MDC1	Q13535	ATR	S329	D330G	330	Missense	proximal	1	no	11.485	7.955	EPSD	COSMIC	10.658	Loss
Atypical_PIKK_ATR_ATR_ST	Q14676	MDC1	Q13535	ATR	S329	S329C	329	Missense	central	0	yes	11.485	0.000	EPSD	COSMIC	10.658	Loss
Atypical_PIKK_ATR_ATR_ST	Q14676	MDC1	Q13535	ATR	S329	D330N	330	Missense	proximal	1	no	11.485	12.623	EPSD	COSMIC	10.658	Up-regulation
Atypical_PIKK_ATR_ATR_ST	Q14676	MDC1	Q13535	ATR	T341	V343I	343	Missense	proximal	2	no	10.689	9.379	EPSD	COSMIC	10.658	Loss
Atypical_PIKK_ATR_ATR_ST	Q14676	MDC1	Q13535	ATR	T341	P342S	342	Missense	proximal	1	no	10.689	9.580	EPSD	COSMIC	10.658	Loss
Atypical_PIKK_ATR_ATR_ST	Q14676	MDC1	Q13535	ATR	S372	Q370R	370	Missense	proximal	-2	no	13.331	13.409	EPSD	COSMIC	10.658	Up-regulation
Atypical_PIKK_ATR_ATR_ST	Q14676	MDC1	Q13535	ATR	S372	Q373L	373	Missense	proximal	1	no	13.331	7.898	EPSD	COSMIC	10.658	Loss
Atypical_PIKK_ATR_ATR_ST	Q14676	MDC1	Q13535	ATR	S394	A388V	388	Missense	distal	-6	no	16.729	16.698	EPSD	COSMIC	10.658	Down-regulation
Atypical_PIKK_ATR_ATR_ST	Q14676	MDC1	Q13535	ATR	S394	E392K	392	Missense	proximal	-2	no	16.729	16.828	EPSD	COSMIC	10.658	Up-regulation
Atypical_PIKK_ATR_ATR_ST	Q14676	MDC1	Q13535	ATR	S422	H418Q	418	Missense	distal	-4	no	14.280	14.461	EPSD	COSMIC	10.658	Up-regulation
Atypical_PIKK_ATR_ATR_ST	Q14676	MDC1	Q13535	ATR	S422	L419Q	419	Missense	distal	-3	no	14.280	14.062	EPSD	COSMIC	10.658	Down-regulation
Atypical_PIKK_ATR_ATR_ST	Q14676	MDC1	Q13535	ATR	S422	I426T	426	Missense	distal	4	no	14.280	13.649	EPSD	COSMIC	10.658	Down-regulation
Atypical_PIKK_ATR_ATR_ST	Q14676	MDC1	Q13535	ATR	S445	R444Q	444	Missense	proximal	-1	no	12.072	12.002	EPSD	COSMIC	10.658	Down-regulation
Atypical_PIKK_ATR_ATR_ST	Q14676	MDC1	Q13535	ATR	S445	T448I	448	Missense	distal	3	no	12.072	12.430	EPSD	COSMIC	10.658	Up-regulation
Atypical_PIKK_ATR_ATR_ST	Q14676	MDC1	Q13535	ATR	S505	H509P	509	Missense	distal	4	no	13.182	13.670	EPSD	COSMIC	10.658	Up-regulation
Atypical_PIKK_ATR_ATR_ST	Q14676	MDC1	Q13535	ATR	S505	D502Y	502	Missense	distal	-3	no	13.182	13.225	EPSD	COSMIC	10.658	Up-regulation
Atypical_PIKK_ATR_ATR_ST	Q14676	MDC1	Q13535	ATR	S513	H509P	509	Missense	distal	-4	no	15.062	15.684	PhosphoSitePlus	COSMIC	10.658	Up-regulation
Atypical_PIKK_ATR_ATR_ST	Q14676	MDC1	Q13535	ATR	T659	Q662H	662	Missense	distal	3	no	11.187	11.590	EPSD	COSMIC	10.658	Up-regulation
Atypical_PIKK_ATR_ATR_ST	Q14676	MDC1	Q13535	ATR	T659	G665R	665	Missense	distal	6	no	11.187	11.033	EPSD	COSMIC	10.658	Down-regulation
Atypical_PIKK_ATR_ATR_ST	Q14676	MDC1	Q13535	ATR	T719	P726A	726	Missense	distal	7	no	13.525	13.432	EPSD	COSMIC	10.658	Down-regulation
Atypical_PIKK_ATR_ATR_ST	Q14676	MDC1	Q13535	ATR	T725	L730P	730	Missense	distal	5	no	10.959	10.964	EPSD	COSMIC	10.658	Up-regulation
Atypical_PIKK_ATR_ATR_ST	Q14676	MDC1	Q13535	ATR	T725	P726A	726	Missense	proximal	1	no	10.959	5.099	EPSD	COSMIC	10.658	Loss
Atypical_PIKK_ATR_ATR_ST	Q14676	MDC1	Q13535	ATR	T765	S763F	763	Missense	proximal	-2	no	10.296	10.895	EPSD	COSMIC;GDSC;CCLE	10.658	Gain
Atypical_PIKK_ATR_ATR_ST	Q14676	MDC1	Q13535	ATR	S874	S874C	874	Missense	central	0	yes	11.030	0.000	EPSD	COSMIC	10.658	Loss
Atypical_PIKK_ATR_ATR_ST	Q14676	MDC1	Q13535	ATR	S874	R871K	871	Missense	distal	-3	no	11.030	10.418	EPSD	COSMIC	10.658	Loss
Atypical_PIKK_ATR_ATR_ST	Q14676	MDC1	Q13535	ATR	S874	G878V	878	Missense	distal	4	no	11.030	10.423	EPSD	COSMIC	10.658	Loss
Atypical_PIKK_ATR_ATR_ST	Q14676	MDC1	Q13535	ATR	T946	V940A	940	Missense	distal	-6	no	13.763	13.794	EPSD	COSMIC	10.658	Up-regulation
Atypical_PIKK_ATR_ATR_ST	Q14676	MDC1	Q13535	ATR	T946	T946I	946	Missense	central	0	yes	13.763	0.000	EPSD	COSMIC	10.658	Loss
Atypical_PIKK_ATR_ATR_ST	Q14676	MDC1	Q13535	ATR	T946	R948S	948	Missense	proximal	2	no	13.763	14.037	EPSD	COSMIC	10.658	Up-regulation
Atypical_PIKK_ATR_ATR_ST	Q14676	MDC1	Q13535	ATR	T946	Q947H	947	Missense	proximal	1	no	13.763	-3.755	EPSD	COSMIC	10.658	Loss
Atypical_PIKK_ATR_ATR_ST	Q14676	MDC1	Q13535	ATR	T946	D945Y	945	Missense	proximal	-1	no	13.763	13.907	EPSD	COSMIC	10.658	Up-regulation
Atypical_PIKK_ATR_ATR_ST	Q14676	MDC1	Q13535	ATR	S955	R948S	948	Missense	distal	-7	no	16.060	16.106	EPSD	COSMIC	10.658	Up-regulation
Atypical_PIKK_ATR_ATR_ST	Q14676	MDC1	Q13535	ATR	S988	P983S	983	Missense	distal	-5	no	12.254	12.225	EPSD	COSMIC	10.658	Down-regulation
Atypical_PIKK_ATR_ATR_ST	Q14676	MDC1	Q13535	ATR	S988	S986F	986	Missense	proximal	-2	no	12.254	12.852	EPSD	COSMIC	10.658	Up-regulation
Atypical_PIKK_ATR_ATR_ST	Q14676	MDC1	Q13535	ATR	S988	P985L	985	Missense	distal	-3	no	12.254	12.549	EPSD	COSMIC	10.658	Up-regulation
Atypical_PIKK_ATR_ATR_ST	Q14676	MDC1	Q13535	ATR	S988	S995F	995	Missense	distal	7	no	12.254	12.316	EPSD	COSMIC	10.658	Up-regulation
Atypical_PIKK_ATR_ATR_ST	Q14676	MDC1	Q13535	ATR	S988	S981A	981	Missense	distal	-7	no	12.254	12.219	EPSD	COSMIC	10.658	Down-regulation
Atypical_PIKK_ATR_ATR_ST	Q14676	MDC1	Q13535	ATR	S1055	S1055A	1055	Missense	central	0	yes	13.939	0.000	EPSD	COSMIC	10.658	Loss
Atypical_PIKK_ATR_ATR_ST	Q14676	MDC1	Q13535	ATR	S1055	L1053F	1053	Missense	proximal	-2	no	13.939	13.835	EPSD	COSMIC	10.658	Down-regulation
Atypical_PIKK_ATR_ATR_ST	Q14676	MDC1	Q13535	ATR	S1055	P1052L	1052	Missense	distal	-3	no	13.939	14.234	EPSD	COSMIC	10.658	Up-regulation
Atypical_PIKK_ATR_ATR_ST	Q14676	MDC1	Q13535	ATR	S1055	S1055F	1055	Missense	central	0	yes	13.939	0.000	EPSD	COSMIC	10.658	Loss
Atypical_PIKK_ATR_ATR_ST	Q14676	MDC1	Q13535	ATR	S1057	S1055A	1055	Missense	proximal	-2	no	12.221	12.996	EPSD	COSMIC	10.658	Up-regulation
Atypical_PIKK_ATR_ATR_ST	Q14676	MDC1	Q13535	ATR	S1057	L1053F	1053	Missense	distal	-4	no	12.221	12.812	EPSD	COSMIC	10.658	Up-regulation
Atypical_PIKK_ATR_ATR_ST	Q14676	MDC1	Q13535	ATR	S1057	P1052L	1052	Missense	distal	-5	no	12.221	12.374	EPSD	COSMIC	10.658	Up-regulation
Atypical_PIKK_ATR_ATR_ST	Q14676	MDC1	Q13535	ATR	S1057	P1064L	1064	Missense	distal	7	no	12.221	12.219	EPSD	COSMIC	10.658	Down-regulation
Atypical_PIKK_ATR_ATR_ST	Q14676	MDC1	Q13535	ATR	S1057	S1055F	1055	Missense	proximal	-2	no	12.221	12.819	EPSD	COSMIC	10.658	Up-regulation
Atypical_PIKK_ATR_ATR_ST	Q14676	MDC1	Q13535	ATR	S1057	P1063H	1063	Missense	distal	6	no	12.221	12.197	EPSD	COSMIC	10.658	Down-regulation
Atypical_PIKK_ATR_ATR_ST	Q14676	MDC1	Q13535	ATR	S1086	R1079C	1079	Missense	distal	-7	no	15.640	15.462	EPSD	COSMIC	10.658	Down-regulation
Atypical_PIKK_ATR_ATR_ST	Q14676	MDC1	Q13535	ATR	S1086	R1079H	1079	Missense	distal	-7	no	15.640	15.692	EPSD	COSMIC	10.658	Up-regulation
Atypical_PIKK_ATR_ATR_ST	Q14676	MDC1	Q13535	ATR	S1086	P1090L	1090	Missense	distal	4	no	15.640	15.790	EPSD	COSMIC	10.658	Up-regulation
Atypical_PIKK_ATR_ATR_ST	Q14676	MDC1	Q13535	ATR	S1086	E1088V	1088	Missense	proximal	2	no	15.640	15.209	EPSD	COSMIC	10.658	Down-regulation
Atypical_PIKK_ATR_ATR_ST	Q14676	MDC1	Q13535	ATR	S1143	T1138S	1138	Missense	distal	-5	no	14.595	14.583	EPSD	COSMIC	10.658	Down-regulation
Atypical_PIKK_ATR_ATR_ST	Q14676	MDC1	Q13535	ATR	S1143	T1142A	1142	Missense	proximal	-1	no	14.595	14.825	EPSD	COSMIC	10.658	Up-regulation
Atypical_PIKK_ATR_ATR_ST	Q14676	MDC1	Q13535	ATR	S1143	A1145T	1145	Missense	proximal	2	no	14.595	14.057	EPSD	COSMIC	10.658	Down-regulation
Atypical_PIKK_ATR_ATR_ST	Q14676	MDC1	Q13535	ATR	S1153	V1155L	1155	Missense	proximal	2	no	10.884	9.281	EPSD	COSMIC	10.658	Loss
Atypical_PIKK_ATR_ATR_ST	Q14676	MDC1	Q13535	ATR	S1153	P1160L	1160	Missense	distal	7	no	10.884	10.882	EPSD	COSMIC	10.658	Down-regulation
Atypical_PIKK_ATR_ATR_ST	Q14676	MDC1	Q13535	ATR	S1184	T1187S	1187	Missense	distal	3	no	13.414	13.763	EPSD	COSMIC	10.658	Up-regulation
Atypical_PIKK_ATR_ATR_ST	Q14676	MDC1	Q13535	ATR	S1184	T1179I	1179	Missense	distal	-5	no	13.414	13.605	EPSD	COSMIC	10.658	Up-regulation
Atypical_PIKK_ATR_ATR_ST	Q14676	MDC1	Q13535	ATR	S1184	V1186A	1186	Missense	proximal	2	no	13.414	12.924	EPSD	COSMIC	10.658	Down-regulation
Atypical_PIKK_ATR_ATR_ST	Q14676	MDC1	Q13535	ATR	S1184	S1184Y	1184	Missense	central	0	yes	13.414	0.000	EPSD	COSMIC	10.658	Loss
Atypical_PIKK_ATR_ATR_ST	Q14676	MDC1	Q13535	ATR	S1184	P1177S	1177	Missense	distal	-7	no	13.414	13.386	EPSD	COSMIC;GDSC	10.658	Down-regulation
Atypical_PIKK_ATR_ATR_ST	Q14676	MDC1	Q13535	ATR	S1184	S1180P	1180	Missense	distal	-4	no	13.414	13.739	EPSD	COSMIC	10.658	Up-regulation
Atypical_PIKK_ATR_ATR_ST	Q14676	MDC1	Q13535	ATR	S1184	Q1185H	1185	Missense	proximal	1	no	13.414	-4.104	EPSD	COSMIC;GDSC;CCLE	10.658	Loss
Atypical_PIKK_ATR_ATR_ST	Q14676	MDC1	Q13535	ATR	T1187	S1194F	1194	Missense	distal	7	no	10.621	10.682	EPSD	COSMIC	10.658	Gain
Atypical_PIKK_ATR_ATR_ST	Q14676	MDC1	Q13535	ATR	T1187	V1186A	1186	Missense	proximal	-1	no	10.621	10.877	EPSD	COSMIC	10.658	Gain
Atypical_PIKK_ATR_ATR_ST	Q14676	MDC1	Q13535	ATR	T1187	S1184Y	1184	Missense	distal	-3	no	10.621	11.457	EPSD	COSMIC	10.658	Gain
Atypical_PIKK_ATR_ATR_ST	Q14676	MDC1	Q13535	ATR	S1194	T1187S	1187	Missense	distal	-7	no	10.954	11.012	EPSD	COSMIC	10.658	Up-regulation
Atypical_PIKK_ATR_ATR_ST	Q14676	MDC1	Q13535	ATR	S1194	S1194F	1194	Missense	central	0	yes	10.954	0.000	EPSD	COSMIC	10.658	Loss
Atypical_PIKK_ATR_ATR_ST	Q14676	MDC1	Q13535	ATR	S1194	S1192N	1192	Missense	proximal	-2	no	10.954	11.803	EPSD	COSMIC	10.658	Up-regulation
Atypical_PIKK_ATR_ATR_ST	Q14676	MDC1	Q13535	ATR	S1194	T1198I	1198	Missense	distal	4	no	10.954	11.585	EPSD	COSMIC	10.658	Up-regulation
Atypical_PIKK_ATR_ATR_ST	Q14676	MDC1	Q13535	ATR	S1194	V1196I	1196	Missense	proximal	2	no	10.954	9.644	EPSD	COSMIC	10.658	Loss
Atypical_PIKK_ATR_ATR_ST	Q14676	MDC1	Q13535	ATR	S1225	R1229M	1229	Missense	distal	4	no	13.057	12.560	EPSD	COSMIC	10.658	Down-regulation
Atypical_PIKK_ATR_ATR_ST	Q14676	MDC1	Q13535	ATR	T1228	R1229M	1229	Missense	proximal	1	no	10.285	13.195	EPSD	COSMIC	10.658	Gain
Atypical_PIKK_ATR_ATR_ST	Q14676	MDC1	Q13535	ATR	T1269	Y1266S	1266	Missense	distal	-3	no	11.956	11.119	EPSD	COSMIC	10.658	Down-regulation
Atypical_PIKK_ATR_ATR_ST	Q14676	MDC1	Q13535	ATR	T1269	N1274S	1274	Missense	distal	5	no	11.956	11.951	EPSD	COSMIC	10.658	Down-regulation
Atypical_PIKK_ATR_ATR_ST	Q14676	MDC1	Q13535	ATR	T1269	A1268V	1268	Missense	proximal	-1	no	11.956	11.699	EPSD	COSMIC	10.658	Down-regulation
Atypical_PIKK_ATR_ATR_ST	Q14676	MDC1	Q13535	ATR	T1269	Y1266F	1266	Missense	distal	-3	no	11.956	11.979	EPSD	COSMIC	10.658	Up-regulation
Atypical_PIKK_ATR_ATR_ST	Q14676	MDC1	Q13535	ATR	T1269	R1272T	1272	Missense	distal	3	no	11.956	12.042	EPSD	COSMIC	10.658	Up-regulation
Atypical_PIKK_ATR_ATR_ST	Q14676	MDC1	Q13535	ATR	T1269	G1271R	1271	Missense	proximal	2	no	11.956	10.743	EPSD	COSMIC	10.658	Down-regulation
Atypical_PIKK_ATR_ATR_ST	Q14676	MDC1	Q13535	ATR	S1276	P1283T	1283	Missense	distal	7	no	11.168	11.177	EPSD	COSMIC	10.658	Up-regulation
Atypical_PIKK_ATR_ATR_ST	Q14676	MDC1	Q13535	ATR	S1276	N1274S	1274	Missense	proximal	-2	no	11.168	10.320	EPSD	COSMIC	10.658	Loss
Atypical_PIKK_ATR_ATR_ST	Q14676	MDC1	Q13535	ATR	S1276	R1272T	1272	Missense	distal	-4	no	11.168	11.380	EPSD	COSMIC	10.658	Up-regulation
Atypical_PIKK_ATR_ATR_ST	Q14676	MDC1	Q13535	ATR	S1276	S1277F	1277	Missense	proximal	1	no	11.168	10.461	EPSD	COSMIC	10.658	Loss
Atypical_PIKK_ATR_ATR_ST	Q14676	MDC1	Q13535	ATR	S1276	G1271R	1271	Missense	distal	-5	no	11.168	11.334	EPSD	COSMIC	10.658	Up-regulation
Atypical_PIKK_ATR_ATR_ST	Q14676	MDC1	Q13535	ATR	T1310	R1311M	1311	Missense	proximal	1	no	9.770	12.680	EPSD	COSMIC	10.658	Gain
Atypical_PIKK_ATR_ATR_ST	Q14676	MDC1	Q13535	ATR	S1317	S1318F	1318	Missense	proximal	1	no	11.318	10.611	EPSD	COSMIC	10.658	Loss
Atypical_PIKK_ATR_ATR_ST	Q14676	MDC1	Q13535	ATR	S1317	R1311M	1311	Missense	distal	-6	no	11.318	11.300	EPSD	COSMIC	10.658	Down-regulation
Atypical_PIKK_ATR_ATR_ST	Q14676	MDC1	Q13535	ATR	S1317	T1324P	1324	Missense	distal	7	no	11.318	11.309	EPSD	COSMIC	10.658	Down-regulation
Atypical_PIKK_ATR_ATR_ST	Q14676	MDC1	Q13535	ATR	S1317	M1316V	1316	Missense	proximal	-1	no	11.318	11.168	EPSD	COSMIC	10.658	Down-regulation
Atypical_PIKK_ATR_ATR_ST	Q14676	MDC1	Q13535	ATR	S1317	S1318A	1318	Missense	proximal	1	no	11.318	6.567	EPSD	COSMIC	10.658	Loss
Atypical_PIKK_ATR_ATR_ST	Q14676	MDC1	Q13535	ATR	S1317	M1316T	1316	Missense	proximal	-1	no	11.318	11.194	EPSD	COSMIC	10.658	Down-regulation
Atypical_PIKK_ATR_ATR_ST	Q14676	MDC1	Q13535	ATR	S1348	R1349Q	1349	Missense	proximal	1	no	4.618	11.613	EPSD	COSMIC	10.658	Gain
Atypical_PIKK_ATR_ATR_ST	Q14676	MDC1	Q13535	ATR	T1351	R1349L	1349	Missense	proximal	-2	no	10.461	10.754	EPSD	COSMIC	10.658	Gain
Atypical_PIKK_ATR_ATR_ST	Q14676	MDC1	Q13535	ATR	S1430	T1433P	1433	Missense	distal	3	no	13.048	13.333	EPSD	COSMIC	10.658	Up-regulation
Atypical_PIKK_ATR_ATR_ST	Q14676	MDC1	Q13535	ATR	S1430	P1428S	1428	Missense	proximal	-2	no	13.048	12.997	EPSD	COSMIC	10.658	Down-regulation
Atypical_PIKK_ATR_ATR_ST	Q14676	MDC1	Q13535	ATR	S1430	R1434S	1434	Missense	distal	4	no	13.048	12.996	EPSD	COSMIC	10.658	Down-regulation
Atypical_PIKK_ATR_ATR_ST	Q14676	MDC1	Q13535	ATR	S1430	Q1431E	1431	Missense	proximal	1	no	13.048	7.127	EPSD	COSMIC	10.658	Loss
Atypical_PIKK_ATR_ATR_ST	Q14676	MDC1	Q13535	ATR	S1430	R1436T	1436	Missense	distal	6	no	13.048	13.397	EPSD	COSMIC	10.658	Up-regulation
Atypical_PIKK_ATR_ATR_ST	Q14676	MDC1	Q13535	ATR	S1430	P1428H	1428	Missense	proximal	-2	no	13.048	12.961	EPSD	COSMIC	10.658	Down-regulation
Atypical_PIKK_ATR_ATR_ST	Q14676	MDC1	Q13535	ATR	T1433	T1433P	1433	Missense	central	0	yes	10.879	0.000	EPSD	COSMIC	10.658	Loss
Atypical_PIKK_ATR_ATR_ST	Q14676	MDC1	Q13535	ATR	T1433	P1428S	1428	Missense	distal	-5	no	10.879	10.850	EPSD	COSMIC	10.658	Down-regulation
Atypical_PIKK_ATR_ATR_ST	Q14676	MDC1	Q13535	ATR	T1433	R1439K	1439	Missense	distal	6	no	10.879	11.161	EPSD	COSMIC	10.658	Up-regulation
Atypical_PIKK_ATR_ATR_ST	Q14676	MDC1	Q13535	ATR	T1433	R1434S	1434	Missense	proximal	1	no	10.879	11.897	EPSD	COSMIC	10.658	Up-regulation
Atypical_PIKK_ATR_ATR_ST	Q14676	MDC1	Q13535	ATR	T1433	Q1431E	1431	Missense	proximal	-2	no	10.879	10.844	EPSD	COSMIC	10.658	Down-regulation
Atypical_PIKK_ATR_ATR_ST	Q14676	MDC1	Q13535	ATR	T1433	R1436T	1436	Missense	distal	3	no	10.879	10.966	EPSD	COSMIC	10.658	Up-regulation
Atypical_PIKK_ATR_ATR_ST	Q14676	MDC1	Q13535	ATR	T1433	P1428H	1428	Missense	distal	-5	no	10.879	10.970	EPSD	COSMIC	10.658	Up-regulation
Atypical_PIKK_ATR_ATR_ST	Q14676	MDC1	Q13535	ATR	S1440	T1433P	1433	Missense	distal	-7	no	11.334	11.420	EPSD	COSMIC	10.658	Up-regulation
Atypical_PIKK_ATR_ATR_ST	Q14676	MDC1	Q13535	ATR	S1440	R1439K	1439	Missense	proximal	-1	no	11.334	11.100	EPSD	COSMIC	10.658	Down-regulation
Atypical_PIKK_ATR_ATR_ST	Q14676	MDC1	Q13535	ATR	S1440	R1434S	1434	Missense	distal	-6	no	11.334	11.252	EPSD	COSMIC	10.658	Down-regulation
Atypical_PIKK_ATR_ATR_ST	Q14676	MDC1	Q13535	ATR	S1440	R1436T	1436	Missense	distal	-4	no	11.334	11.546	EPSD	COSMIC	10.658	Up-regulation
Atypical_PIKK_ATR_ATR_ST	Q14676	MDC1	Q13535	ATR	S1458	T1459P	1459	Missense	proximal	1	no	7.635	12.286	EPSD	COSMIC	10.658	Gain
Atypical_PIKK_ATR_ATR_ST	Q14676	MDC1	Q13535	ATR	S1471	T1470A	1470	Missense	proximal	-1	no	13.703	13.933	EPSD	COSMIC	10.658	Up-regulation
Atypical_PIKK_ATR_ATR_ST	Q14676	MDC1	Q13535	ATR	S1471	Q1472K	1472	Missense	proximal	1	no	13.703	2.737	EPSD	COSMIC	10.658	Loss
Atypical_PIKK_ATR_ATR_ST	Q14676	MDC1	Q13535	ATR	S1471	S1471F	1471	Missense	central	0	yes	13.703	0.000	EPSD	COSMIC	10.658	Loss
Atypical_PIKK_ATR_ATR_ST	Q14676	MDC1	Q13535	ATR	S1471	P1469S	1469	Missense	proximal	-2	no	13.703	13.652	EPSD	COSMIC	10.658	Down-regulation
Atypical_PIKK_ATR_ATR_ST	Q14676	MDC1	Q13535	ATR	S1471	V1465L	1465	Missense	distal	-6	no	13.703	13.735	EPSD	COSMIC	10.658	Up-regulation
Atypical_PIKK_ATR_ATR_ST	Q14676	MDC1	Q13535	ATR	T1474	T1470A	1470	Missense	distal	-4	no	10.756	11.363	EPSD	COSMIC	10.658	Up-regulation
Atypical_PIKK_ATR_ATR_ST	Q14676	MDC1	Q13535	ATR	T1474	Q1472K	1472	Missense	proximal	-2	no	10.756	10.820	EPSD	COSMIC	10.658	Up-regulation
Atypical_PIKK_ATR_ATR_ST	Q14676	MDC1	Q13535	ATR	T1474	S1471F	1471	Missense	distal	-3	no	10.756	11.615	EPSD	COSMIC	10.658	Up-regulation
Atypical_PIKK_ATR_ATR_ST	Q14676	MDC1	Q13535	ATR	T1474	P1469S	1469	Missense	distal	-5	no	10.756	10.727	EPSD	COSMIC	10.658	Down-regulation
Atypical_PIKK_ATR_ATR_ST	Q14676	MDC1	Q13535	ATR	T1474	D1479H	1479	Missense	distal	5	no	10.756	10.752	EPSD	COSMIC	10.658	Down-regulation
Atypical_PIKK_ATR_ATR_ST	Q14676	MDC1	Q13535	ATR	T1474	S1481T	1481	Missense	distal	7	no	10.756	10.928	EPSD	COSMIC	10.658	Up-regulation
Atypical_PIKK_ATR_ATR_ST	Q14676	MDC1	Q13535	ATR	S1522	R1521W	1521	Missense	proximal	-1	no	10.588	10.686	EPSD	COSMIC	10.658	Gain
Atypical_PIKK_ATR_ATR_ST	Q14676	MDC1	Q13535	ATR	S1553	R1554Q	1554	Missense	proximal	1	no	6.373	13.369	EPSD	COSMIC	10.658	Gain
Atypical_PIKK_ATR_ATR_ST	Q14676	MDC1	Q13535	ATR	S1563	G1558C	1558	Missense	distal	-5	no	10.615	10.788	EPSD	COSMIC	10.658	Gain
Atypical_PIKK_ATR_ATR_ST	Q14676	MDC1	Q13535	ATR	S1563	R1562M	1562	Missense	proximal	-1	no	10.615	10.659	EPSD	COSMIC	10.658	Gain
Atypical_PIKK_ATR_ATR_ST	Q14676	MDC1	Q13535	ATR	S1604	T1601I	1601	Missense	distal	-3	no	10.741	10.486	EPSD	COSMIC	10.658	Loss
Atypical_PIKK_ATR_ATR_ST	Q14676	MDC1	Q13535	ATR	S1604	C1599G	1599	Missense	distal	-5	no	10.741	10.567	EPSD	COSMIC	10.658	Loss
Atypical_PIKK_ATR_ATR_ST	Q14676	MDC1	Q13535	ATR	S1604	S1604F	1604	Missense	central	0	yes	10.741	0.000	EPSD	COSMIC	10.658	Loss
Atypical_PIKK_ATR_ATR_ST	Q14676	MDC1	Q13535	ATR	S1604	P1609A	1609	Missense	distal	5	no	10.741	10.740	EPSD	COSMIC	10.658	Down-regulation
Atypical_PIKK_ATR_ATR_ST	Q14676	MDC1	Q13535	ATR	S1702	P1698L	1698	Missense	distal	-4	no	12.752	11.552	EPSD	COSMIC	10.658	Down-regulation
Atypical_PIKK_ATR_ATR_ST	Q14676	MDC1	Q13535	ATR	S1702	T1705I	1705	Missense	distal	3	no	12.752	13.110	EPSD	COSMIC	10.658	Up-regulation
Atypical_PIKK_ATR_ATR_ST	Q14676	MDC1	Q13535	ATR	S1702	T1706I	1706	Missense	distal	4	no	12.752	13.384	EPSD	COSMIC	10.658	Up-regulation
Atypical_PIKK_ATR_ATR_ST	Q14676	MDC1	Q13535	ATR	S1711	I1710M	1710	Missense	proximal	-1	no	12.191	12.089	EPSD	COSMIC	10.658	Down-regulation
Atypical_PIKK_ATR_ATR_ST	Q14676	MDC1	Q13535	ATR	S1711	T1705I	1705	Missense	distal	-6	no	12.191	12.189	EPSD	COSMIC	10.658	Down-regulation
Atypical_PIKK_ATR_ATR_ST	Q14676	MDC1	Q13535	ATR	S1711	P1718L	1718	Missense	distal	7	no	12.191	12.190	EPSD	COSMIC	10.658	Down-regulation
Atypical_PIKK_ATR_ATR_ST	Q14676	MDC1	Q13535	ATR	S1711	T1706I	1706	Missense	distal	-5	no	12.191	12.382	EPSD	COSMIC	10.658	Up-regulation
Atypical_PIKK_ATR_ATR_ST	Q14676	MDC1	Q13535	ATR	T1716	I1710M	1710	Missense	distal	-6	no	12.022	12.003	EPSD	COSMIC	10.658	Down-regulation
Atypical_PIKK_ATR_ATR_ST	Q14676	MDC1	Q13535	ATR	T1716	P1718L	1718	Missense	proximal	2	no	12.022	10.741	EPSD	COSMIC	10.658	Down-regulation
Atypical_PIKK_ATR_ATR_ST	Q14676	MDC1	Q13535	ATR	S1786	K1790R	1790	Missense	distal	4	no	11.649	11.832	EPSD	COSMIC	10.658	Up-regulation
Atypical_PIKK_ATR_ATR_ST	Q14676	MDC1	Q13535	ATR	S1786	K1790M	1790	Missense	distal	4	no	11.649	11.335	EPSD	COSMIC	10.658	Down-regulation
Atypical_PIKK_ATR_ATR_ST	Q14676	MDC1	Q13535	ATR	T1800	P1801Q	1801	Missense	proximal	1	no	8.258	13.125	EPSD	COSMIC	10.658	Gain
Atypical_PIKK_ATR_ATR_ST	Q14676	MDC1	Q13535	ATR	S1833	V1837M	1837	Missense	distal	4	no	13.250	12.643	EPSD	COSMIC	10.658	Down-regulation
Atypical_PIKK_ATR_ATR_ST	Q14676	MDC1	Q13535	ATR	S1833	S1833F	1833	Missense	central	0	yes	13.250	0.000	EPSD	COSMIC	10.658	Loss
Atypical_PIKK_ATR_ATR_ST	Q14676	MDC1	Q13535	ATR	T1858	R1864T	1864	Missense	distal	6	no	11.139	11.488	EPSD	COSMIC	10.658	Up-regulation
Atypical_PIKK_ATR_ATR_ST	Q14676	MDC1	Q13535	ATR	T1858	V1857L	1857	Missense	proximal	-1	no	11.139	11.354	EPSD	COSMIC	10.658	Up-regulation
Atypical_PIKK_ATR_ATR_ST	Q14676	MDC1	Q13535	ATR	T1858	D1855N	1855	Missense	distal	-3	no	11.139	11.431	EPSD	COSMIC	10.658	Up-regulation
Atypical_PIKK_ATR_ATR_ST	Q14676	MDC1	Q13535	ATR	T1858	K1863N	1863	Missense	distal	5	no	11.139	11.140	EPSD	COSMIC	10.658	Up-regulation
Atypical_PIKK_ATR_ATR_ST	Q6PGQ7	BORA	Q13535	ATR	S278	T276A	276	Missense	proximal	-2	no	12.398	12.871	EPSD	COSMIC	10.658	Up-regulation
Atypical_PIKK_ATR_ATR_ST	Q13098	GPS1	Q13535	ATR	S240	T242S	242	Missense	proximal	2	no	14.957	15.348	EPSD	COSMIC	10.658	Up-regulation
Atypical_PIKK_ATR_ATR_ST	Q13098	GPS1	Q13535	ATR	S240	T247S	247	Missense	distal	7	no	14.957	14.785	EPSD	COSMIC	10.658	Down-regulation
Atypical_PIKK_ATR_ATR_ST	Q13098	GPS1	Q13535	ATR	S240	D239G	239	Missense	proximal	-1	no	14.957	14.863	EPSD	COSMIC	10.658	Down-regulation
Atypical_PIKK_ATR_ATR_ST	Q13098	GPS1	Q13535	ATR	T367	R370H	370	Missense	distal	3	no	10.622	11.030	EPSD	COSMIC	10.658	Gain
Atypical_PIKK_ATR_ATR_ST	Q13098	GPS1	Q13535	ATR	T367	R370C	370	Missense	distal	3	no	10.622	10.755	EPSD	COSMIC	10.658	Gain
Atypical_PIKK_ATR_ATR_ST	Q13098	GPS1	Q13535	ATR	S474	E472Q	472	Missense	proximal	-2	no	15.933	15.968	PhosphoSitePlus	COSMIC	10.658	Up-regulation
Atypical_PIKK_ATR_ATR_ST	Q13098	GPS1	Q13535	ATR	S474	S468T	468	Missense	distal	-6	no	15.933	16.019	PhosphoSitePlus	COSMIC	10.658	Up-regulation
Atypical_PIKK_ATR_ATR_ST	Q13098	GPS1	Q13535	ATR	S474	L478P	478	Missense	distal	4	no	15.933	15.782	PhosphoSitePlus	COSMIC	10.658	Down-regulation
Atypical_PIKK_ATR_ATR_ST	Q13098	GPS1	Q13535	ATR	S483	L478P	478	Missense	distal	-5	no	10.659	10.506	EPSD	COSMIC	10.658	Loss
Atypical_PIKK_ATR_ATR_ST	Q13098	GPS1	Q13535	ATR	S483	S483I	483	Missense	central	0	yes	10.659	0.000	EPSD	COSMIC	10.658	Loss
Atypical_PIKK_ATR_ATR_ST	O43542	XRCC3	Q13535	ATR	T241	L242Q	242	Missense	proximal	1	no	5.357	10.791	EPSD	COSMIC	10.658	Gain
Atypical_PIKK_ATR_ATR_ST	O00213	APBB1	Q13535	ATR	S287	P283L	283	Missense	distal	-4	no	11.262	10.062	EPSD	COSMIC	10.658	Loss
Atypical_PIKK_ATR_ATR_ST	O00213	APBB1	Q13535	ATR	S287	P288T	288	Missense	proximal	1	no	11.262	6.610	EPSD	COSMIC	10.658	Loss
Atypical_PIKK_ATR_ATR_ST	O00213	APBB1	Q13535	ATR	S287	S293I	293	Missense	distal	6	no	11.262	10.989	EPSD	COSMIC	10.658	Down-regulation
Atypical_PIKK_ATR_ATR_ST	O00213	APBB1	Q13535	ATR	S287	R285P	285	Missense	proximal	-2	no	11.262	10.904	EPSD	COSMIC	10.658	Down-regulation
Atypical_PIKK_ATR_ATR_ST	O00213	APBB1	Q13535	ATR	S289	E296V	296	Missense	distal	7	no	16.933	17.182	EPSD	COSMIC	10.658	Up-regulation
Atypical_PIKK_ATR_ATR_ST	O00213	APBB1	Q13535	ATR	S289	P283L	283	Missense	distal	-6	no	16.933	16.997	EPSD	COSMIC	10.658	Up-regulation
Atypical_PIKK_ATR_ATR_ST	O00213	APBB1	Q13535	ATR	S289	P288T	288	Missense	proximal	-1	no	16.933	16.765	EPSD	COSMIC	10.658	Down-regulation
Atypical_PIKK_ATR_ATR_ST	O00213	APBB1	Q13535	ATR	S289	S293I	293	Missense	distal	4	no	16.933	17.616	EPSD	COSMIC	10.658	Up-regulation
Atypical_PIKK_ATR_ATR_ST	O00213	APBB1	Q13535	ATR	S289	R285P	285	Missense	distal	-4	no	16.933	17.557	EPSD	COSMIC	10.658	Up-regulation
Atypical_PIKK_ATR_ATR_ST	O00213	APBB1	Q13535	ATR	S322	E328K	328	Missense	distal	6	no	13.484	13.285	EPSD	COSMIC	10.658	Down-regulation
Atypical_PIKK_ATR_ATR_ST	P55072	VCP	Q13535	ATR	T347	I353T	353	Missense	distal	6	no	12.211	12.437	EPSD	COSMIC	10.658	Up-regulation
Atypical_PIKK_ATR_ATR_ST	P55072	VCP	Q13535	ATR	T347	I353N	353	Missense	distal	6	no	12.211	12.598	EPSD	COSMIC	10.658	Up-regulation
Atypical_PIKK_ATR_ATR_ST	P55072	VCP	Q13535	ATR	S457	R453W	453	Missense	distal	-4	no	15.584	16.042	EPSD	COSMIC	10.658	Up-regulation
Atypical_PIKK_ATR_ATR_ST	P55072	VCP	Q13535	ATR	S457	L456V	456	Missense	proximal	-1	no	15.584	15.369	EPSD	COSMIC	10.658	Down-regulation
Atypical_PIKK_ATR_ATR_ST	P55072	VCP	Q13535	ATR	S664	A667V	667	Missense	distal	3	no	10.184	10.944	EPSD	COSMIC	10.658	Gain
Atypical_PIKK_ATR_ATR_ST	P55072	VCP	Q13535	ATR	S765	R766W	766	Missense	proximal	1	no	10.946	11.019	EPSD	COSMIC	10.658	Up-regulation
Atypical_PIKK_ATR_ATR_ST	P55072	VCP	Q13535	ATR	S765	R766Q	766	Missense	proximal	1	no	10.946	17.942	EPSD	COSMIC;CCLE	10.658	Up-regulation
Atypical_PIKK_ATR_ATR_ST	P55072	VCP	Q13535	ATR	S765	G769A	769	Missense	distal	4	no	10.946	10.479	EPSD	COSMIC	10.658	Loss
Atypical_PIKK_ATR_ATR_ST	P55072	VCP	Q13535	ATR	S784	T791P	791	Missense	distal	7	no	15.380	15.371	PhosphoSitePlus	COSMIC	10.658	Down-regulation
Atypical_PIKK_ATR_ATR_ST	Q8TAQ2	SMARCC2	Q13535	ATR	S302	P305S	305	Missense	distal	3	no	11.057	11.121	EPSD	COSMIC	10.658	Up-regulation
Atypical_PIKK_ATR_ATR_ST	Q8TAQ2	SMARCC2	Q13535	ATR	S302	P307L	307	Missense	distal	5	no	11.057	11.052	EPSD	COSMIC	10.658	Down-regulation
Atypical_PIKK_ATR_ATR_ST	Q8TAQ2	SMARCC2	Q13535	ATR	S347	P348S	348	Missense	proximal	1	no	12.264	11.155	EPSD	COSMIC	10.658	Down-regulation
Atypical_PIKK_ATR_ATR_ST	Q8TAQ2	SMARCC2	Q13535	ATR	S387	G392D	392	Missense	distal	5	no	12.345	12.349	EPSD	COSMIC	10.658	Up-regulation
Atypical_PIKK_ATR_ATR_ST	Q8TAQ2	SMARCC2	Q13535	ATR	T400	N402S	402	Missense	proximal	2	no	10.814	10.501	EPSD	COSMIC;GDSC;CCLE	10.658	Loss
Atypical_PIKK_ATR_ATR_ST	Q8TAQ2	SMARCC2	Q13535	ATR	T400	E395K	395	Missense	distal	-5	no	10.814	10.895	EPSD	COSMIC	10.658	Up-regulation
Atypical_PIKK_ATR_ATR_ST	Q8TAQ2	SMARCC2	Q13535	ATR	T400	N398T	398	Missense	proximal	-2	no	10.814	10.267	EPSD	COSMIC	10.658	Loss
Atypical_PIKK_ATR_ATR_ST	Q8TAQ2	SMARCC2	Q13535	ATR	S555	M558T	558	Missense	distal	3	no	15.275	15.618	EPSD	COSMIC	10.658	Up-regulation
Atypical_PIKK_ATR_ATR_ST	Q8TAQ2	SMARCC2	Q13535	ATR	S745	R750W	750	Missense	distal	5	no	11.802	11.803	EPSD	COSMIC	10.658	Up-regulation
Atypical_PIKK_ATR_ATR_ST	Q8TAQ2	SMARCC2	Q13535	ATR	S969	G968C	968	Missense	proximal	-1	no	16.789	17.247	PhosphoSitePlus	COSMIC	10.658	Up-regulation
Atypical_PIKK_ATR_ATR_ST	Q8TAQ2	SMARCC2	Q13535	ATR	S969	G968V	968	Missense	proximal	-1	no	16.789	16.716	PhosphoSitePlus	COSMIC	10.658	Down-regulation
Atypical_PIKK_ATR_ATR_ST	Q8TAQ2	SMARCC2	Q13535	ATR	S969	Q970K	970	Missense	proximal	1	no	16.789	5.823	PhosphoSitePlus	COSMIC	10.658	Loss
Atypical_PIKK_ATR_ATR_ST	Q8TAQ2	SMARCC2	Q13535	ATR	S969	S969F	969	Missense	central	0	yes	16.789	0.000	PhosphoSitePlus	COSMIC	10.658	Loss
Atypical_PIKK_ATR_ATR_ST	Q8N163	CCAR2	Q13535	ATR	S43	N45T	45	Missense	proximal	2	no	12.854	12.150	EPSD	COSMIC	10.658	Down-regulation
Atypical_PIKK_ATR_ATR_ST	Q8N163	CCAR2	Q13535	ATR	S43	E41V	41	Missense	proximal	-2	no	12.854	12.814	EPSD	COSMIC	10.658	Down-regulation
Atypical_PIKK_ATR_ATR_ST	Q8N163	CCAR2	Q13535	ATR	S43	A46V	46	Missense	distal	3	no	12.854	13.615	EPSD	COSMIC	10.658	Up-regulation
Atypical_PIKK_ATR_ATR_ST	Q8N163	CCAR2	Q13535	ATR	S302	E296K	296	Missense	distal	-6	no	10.933	10.886	EPSD	COSMIC	10.658	Down-regulation
Atypical_PIKK_ATR_ATR_ST	Q8N163	CCAR2	Q13535	ATR	S302	I298V	298	Missense	distal	-4	no	10.933	11.807	EPSD	COSMIC	10.658	Up-regulation
Atypical_PIKK_ATR_ATR_ST	Q8N163	CCAR2	Q13535	ATR	T454	P453T	453	Missense	proximal	-1	no	16.955	16.787	PhosphoSitePlus	COSMIC	10.658	Down-regulation
Atypical_PIKK_ATR_ATR_ST	Q8N163	CCAR2	Q13535	ATR	T454	E449A	449	Missense	distal	-5	no	16.955	17.135	PhosphoSitePlus	COSMIC	10.658	Up-regulation
Atypical_PIKK_ATR_ATR_ST	Q8N163	CCAR2	Q13535	ATR	T484	A487V	487	Missense	distal	3	no	10.039	10.800	EPSD	COSMIC	10.658	Gain
Atypical_PIKK_ATR_ATR_ST	Q8N163	CCAR2	Q13535	ATR	T484	P485Q	485	Missense	proximal	1	no	10.039	14.907	EPSD	COSMIC	10.658	Gain
Atypical_PIKK_ATR_ATR_ST	Q8N163	CCAR2	Q13535	ATR	T489	P485A	485	Missense	distal	-4	no	12.293	12.488	EPSD	COSMIC	10.658	Up-regulation
Atypical_PIKK_ATR_ATR_ST	Q8N163	CCAR2	Q13535	ATR	T489	A487V	487	Missense	proximal	-2	no	12.293	11.773	EPSD	COSMIC	10.658	Down-regulation
Atypical_PIKK_ATR_ATR_ST	Q8N163	CCAR2	Q13535	ATR	T489	P485Q	485	Missense	distal	-4	no	12.293	11.851	EPSD	COSMIC	10.658	Down-regulation
Atypical_PIKK_ATR_ATR_ST	Q8N163	CCAR2	Q13535	ATR	S626	K623Q	623	Missense	distal	-3	no	10.531	10.959	EPSD	COSMIC;GDSC;CCLE	10.658	Gain
Atypical_PIKK_ATR_ATR_ST	O75717	WDHD1	Q13535	ATR	S126	S127N	127	Missense	proximal	1	no	9.736	11.437	EPSD	COSMIC	10.658	Gain
Atypical_PIKK_ATR_ATR_ST	O75717	WDHD1	Q13535	ATR	S127	S127N	127	Missense	central	0	yes	12.344	0.000	EPSD	COSMIC	10.658	Loss
Atypical_PIKK_ATR_ATR_ST	O75717	WDHD1	Q13535	ATR	S127	Q128L	128	Missense	proximal	1	no	12.344	6.910	EPSD	COSMIC	10.658	Loss
Atypical_PIKK_ATR_ATR_ST	O75717	WDHD1	Q13535	ATR	S127	F132L	132	Missense	distal	5	no	12.344	12.339	EPSD	COSMIC	10.658	Down-regulation
Atypical_PIKK_ATR_ATR_ST	O75717	WDHD1	Q13535	ATR	S387	S383A	383	Missense	distal	-4	no	11.514	12.035	EPSD	COSMIC	10.658	Up-regulation
Atypical_PIKK_ATR_ATR_ST	O75717	WDHD1	Q13535	ATR	S416	T415A	415	Missense	proximal	-1	no	16.623	16.854	EPSD	COSMIC	10.658	Up-regulation
Atypical_PIKK_ATR_ATR_ST	O75717	WDHD1	Q13535	ATR	T826	A825T	825	Missense	proximal	-1	no	13.519	13.289	PhosphoSitePlus	COSMIC	10.658	Down-regulation
Atypical_PIKK_ATR_ATR_ST	O75717	WDHD1	Q13535	ATR	S853	N847H	847	Missense	distal	-6	no	10.850	10.873	EPSD	COSMIC	10.658	Up-regulation
Atypical_PIKK_ATR_ATR_ST	O75717	WDHD1	Q13535	ATR	S907	A902E	902	Missense	distal	-5	no	16.617	16.437	EPSD	COSMIC	10.658	Down-regulation
Atypical_PIKK_ATR_ATR_ST	O75717	WDHD1	Q13535	ATR	S907	R910L	910	Missense	distal	3	no	16.617	16.385	EPSD	COSMIC	10.658	Down-regulation
Atypical_PIKK_ATR_ATR_ST	O75717	WDHD1	Q13535	ATR	S907	P913F	913	Missense	distal	6	no	16.617	16.756	EPSD	COSMIC	10.658	Up-regulation
Atypical_PIKK_ATR_ATR_ST	O75717	WDHD1	Q13535	ATR	S907	Q908K	908	Missense	proximal	1	no	16.617	5.651	EPSD	COSMIC	10.658	Loss
Atypical_PIKK_ATR_ATR_ST	O75717	WDHD1	Q13535	ATR	S907	R910Q	910	Missense	distal	3	no	16.617	16.622	EPSD	COSMIC	10.658	Up-regulation
Atypical_PIKK_ATR_ATR_ST	O75717	WDHD1	Q13535	ATR	S1090	V1087F	1087	Missense	distal	-3	no	10.801	11.220	EPSD	COSMIC	10.658	Up-regulation
Atypical_PIKK_ATR_ATR_ST	O75717	WDHD1	Q13535	ATR	S1090	E1089G	1089	Missense	proximal	-1	no	10.801	10.753	EPSD	COSMIC	10.658	Down-regulation
Atypical_PIKK_ATR_ATR_ST	P49006	MARCKSL1	Q13535	ATR	S48	G44D	44	Missense	distal	-4	no	9.974	11.323	EPSD	COSMIC	10.658	Gain
Atypical_PIKK_ATR_ATR_ST	P49006	MARCKSL1	Q13535	ATR	S71	I65V	65	Missense	distal	-6	no	16.420	16.413	PhosphoSitePlus	COSMIC	10.658	Down-regulation
Atypical_PIKK_ATR_ATR_ST	P49006	MARCKSL1	Q13535	ATR	S116	G114D	114	Missense	proximal	-2	no	10.725	10.804	EPSD	COSMIC	10.658	Up-regulation
Atypical_PIKK_ATR_ATR_ST	P49006	MARCKSL1	Q13535	ATR	S151	A156T	156	Missense	distal	5	no	16.276	16.273	EPSD	COSMIC	10.658	Down-regulation
STE_STE20_SLK_STK10_ST	P35241	RDX	O94804	STK10	T66	E73K	73	Missense	distal	7	no	2.772	2.834	EPSD	COSMIC	2.434	Up-regulation
STE_STE20_SLK_STK10_ST	P35241	RDX	O94804	STK10	T564	G571C	571	Missense	distal	7	no	8.215	8.199	PhosphoSitePlus	COSMIC	2.434	Down-regulation
STE_STE20_SLK_STK10_ST	P35241	RDX	O94804	STK10	T564	R559C	559	Missense	distal	-5	no	8.215	8.192	PhosphoSitePlus	COSMIC	2.434	Down-regulation
STE_STE20_SLK_STK10_ST	P15311	EZR	O94804	STK10	T235	P236L	236	Missense	proximal	1	no	3.447	4.128	EPSD	COSMIC	2.434	Up-regulation
STE_STE20_SLK_STK10_ST	P15311	EZR	O94804	STK10	T497	A494P	494	Missense	distal	-3	no	3.307	3.368	EPSD	COSMIC	2.434	Up-regulation
STE_STE20_SLK_STK10_ST	P15311	EZR	O94804	STK10	T497	T497M	497	Missense	central	0	yes	3.307	0.000	EPSD	COSMIC;GDSC	2.434	Loss
STE_STE20_SLK_STK10_ST	P15311	EZR	O94804	STK10	T497	E492D	492	Missense	distal	-5	no	3.307	3.287	EPSD	COSMIC	2.434	Down-regulation
STE_STE20_SLK_STK10_ST	P53350	PLK1	O94804	STK10	T210	G205V	205	Missense	distal	-5	no	7.551	7.522	PhosphoSitePlus	COSMIC	2.434	Down-regulation
STE_STE20_SLK_STK10_ST	P53350	PLK1	O94804	STK10	T341	L347F	347	Missense	distal	6	no	2.783	2.777	EPSD	COSMIC	2.434	Down-regulation
STE_STE20_SLK_STK10_ST	P53350	PLK1	O94804	STK10	T341	R337Q	337	Missense	distal	-4	no	2.783	2.885	EPSD	COSMIC	2.434	Up-regulation
STE_STE20_SLK_STK10_ST	P53350	PLK1	O94804	STK10	T341	S335R	335	Missense	distal	-6	no	2.783	2.746	EPSD	COSMIC;GDSC;CCLE	2.434	Down-regulation
STE_STE20_SLK_STK10_ST	P26038	MSN	O94804	STK10	T66	R71W	71	Missense	distal	5	no	2.677	2.664	EPSD	COSMIC	2.434	Down-regulation
STE_STE20_SLK_STK10_ST	P26038	MSN	O94804	STK10	T66	T66A	66	Missense	central	0	yes	2.677	0.000	EPSD	COSMIC	2.434	Loss
STE_STE20_SLK_STK10_ST	P26038	MSN	O94804	STK10	S74	F80L	80	Missense	distal	6	no	3.891	3.898	EPSD	COSMIC	2.434	Up-regulation
STE_STE20_SLK_STK10_ST	P26038	MSN	O94804	STK10	S74	R71W	71	Missense	distal	-3	no	3.891	3.303	EPSD	COSMIC	2.434	Down-regulation
STE_STE20_SLK_STK10_ST	P26038	MSN	O94804	STK10	T558	R560H	560	Missense	proximal	2	no	8.375	8.347	PhosphoSitePlus	COSMIC;GDSC;CCLE	2.434	Down-regulation
STE_STE20_SLK_STK10_ST	P26038	MSN	O94804	STK10	T558	K555R	555	Missense	distal	-3	no	8.375	7.637	PhosphoSitePlus	COSMIC	2.434	Down-regulation
TK_Abl_ABL2_Y	P42684	ABL2	P42684	ABL2	Y261	T257K	257	Missense	distal	-4	no	37.183	37.239	PhosphoSitePlus;EPSD	COSMIC	19.113	Up-regulation
TK_Abl_ABL2_Y	P42684	ABL2	P42684	ABL2	Y261	A263P	263	Missense	proximal	2	no	37.183	37.255	PhosphoSitePlus;EPSD	COSMIC	19.113	Up-regulation
TK_Abl_ABL2_Y	P42684	ABL2	P42684	ABL2	Y261	P264L	264	Missense	distal	3	no	37.183	28.874	PhosphoSitePlus;EPSD	COSMIC	19.113	Down-regulation
TK_Abl_ABL2_Y	P42684	ABL2	P42684	ABL2	Y272	S275P	275	Missense	distal	3	no	32.100	43.190	EPSD	COSMIC	19.113	Up-regulation
TK_Abl_ABL2_Y	P42684	ABL2	P42684	ABL2	Y272	P276H	276	Missense	distal	4	no	32.100	32.313	EPSD	COSMIC	19.113	Up-regulation
TK_Abl_ABL2_Y	P42684	ABL2	P42684	ABL2	Y272	H278Y	278	Missense	distal	6	no	32.100	31.586	EPSD	COSMIC	19.113	Down-regulation
TK_Abl_ABL2_Y	P42684	ABL2	P42684	ABL2	Y272	D279N	279	Missense	distal	7	no	32.100	31.411	EPSD	COSMIC	19.113	Down-regulation
TK_Abl_ABL2_Y	P42684	ABL2	P42684	ABL2	Y439	H442Y	442	Missense	distal	3	no	33.502	30.974	EPSD;PhosphoSitePlus	COSMIC	19.113	Down-regulation
TK_Abl_ABL2_Y	P42684	ABL2	P42684	ABL2	Y568	P573R	573	Missense	distal	5	no	34.896	35.943	EPSD	COSMIC	19.113	Up-regulation
TK_Abl_ABL2_Y	P42684	ABL2	P42684	ABL2	Y568	R571Q	571	Missense	distal	3	no	34.896	34.274	EPSD	COSMIC;CCLE	19.113	Down-regulation
TK_Abl_ABL2_Y	P42684	ABL2	P42684	ABL2	Y568	S564F	564	Missense	distal	-4	no	34.896	29.647	EPSD	COSMIC	19.113	Down-regulation
TK_Abl_ABL2_Y	P42684	ABL2	P42684	ABL2	Y568	L572I	572	Missense	distal	4	no	34.896	35.360	EPSD	COSMIC	19.113	Up-regulation
TK_Abl_ABL2_Y	P42684	ABL2	P42684	ABL2	Y568	I574M	574	Missense	distal	6	no	34.896	34.720	EPSD	COSMIC	19.113	Down-regulation
TK_Abl_ABL2_Y	P42684	ABL2	P42684	ABL2	Y568	S563L	563	Missense	distal	-5	no	34.896	31.282	EPSD	COSMIC	19.113	Down-regulation
TK_Abl_ABL2_Y	P42684	ABL2	P42684	ABL2	Y683	T686M	686	Missense	distal	3	no	36.266	31.747	EPSD	COSMIC	19.113	Down-regulation
TK_Abl_ABL2_Y	P42684	ABL2	P42684	ABL2	Y683	N688D	688	Missense	distal	5	no	36.266	35.008	EPSD	COSMIC	19.113	Down-regulation
TK_Abl_ABL2_Y	P17676	CEBPB	P42684	ABL2	Y137	G143V	143	Missense	distal	6	no	21.513	21.182	EPSD	COSMIC;CCLE	19.113	Down-regulation
TK_Abl_ABL2_Y	P01112	HRAS	P42684	ABL2	Y137	A134S	134	Missense	distal	-3	no	31.133	31.107	PhosphoSitePlus	COSMIC;GDSC;CCLE	19.113	Down-regulation
TK_Abl_ABL2_Y	P01112	HRAS	P42684	ABL2	Y137	Q131E	131	Missense	distal	-6	no	31.133	30.471	PhosphoSitePlus	COSMIC	19.113	Down-regulation
TK_Abl_ABL2_Y	P01112	HRAS	P42684	ABL2	Y137	L133R	133	Missense	distal	-4	no	31.133	33.303	PhosphoSitePlus	COSMIC;GDSC;CCLE	19.113	Up-regulation
TK_Abl_ABL2_Y	P01112	HRAS	P42684	ABL2	Y137	D132V	132	Missense	distal	-5	no	31.133	28.442	PhosphoSitePlus	COSMIC	19.113	Down-regulation
TK_Abl_ABL2_Y	P01112	HRAS	P42684	ABL2	Y137	Y137D	137	Missense	central	0	yes	31.133	0.000	PhosphoSitePlus	COSMIC	19.113	Loss
TK_Abl_ABL2_Y	P01112	HRAS	P42684	ABL2	Y137	T144I	144	Missense	distal	7	no	31.133	31.406	PhosphoSitePlus	COSMIC	19.113	Up-regulation
TK_Abl_ABL2_Y	P46108	CRK	P42684	ABL2	Y221	P216S	216	Missense	distal	-5	no	38.776	40.154	PhosphoSitePlus	COSMIC	19.113	Up-regulation
TK_Abl_ABL2_Y	P46108	CRK	P42684	ABL2	Y239	N235D	235	Missense	distal	-4	no	22.449	22.395	EPSD	COSMIC	19.113	Down-regulation
TK_Abl_ABL2_Y	P10636	MAPT	P42684	ABL2	Y514	G521V	521	Missense	distal	7	no	39.019	39.135	EPSD	COSMIC	19.113	Up-regulation
TK_Abl_ABL2_Y	P10636	MAPT	P42684	ABL2	Y514	G518V	518	Missense	distal	4	no	39.019	38.486	EPSD	COSMIC	19.113	Down-regulation
TK_Abl_ABL2_Y	P10636	MAPT	P42684	ABL2	Y514	R511C	511	Missense	distal	-3	no	39.019	39.155	EPSD	COSMIC;CCLE	19.113	Up-regulation
TK_Abl_ABL2_Y	P10636	MAPT	P42684	ABL2	Y514	G509V	509	Missense	distal	-5	no	39.019	35.048	EPSD	COSMIC	19.113	Down-regulation
TK_Abl_ABL2_Y	P10636	MAPT	P42684	ABL2	Y627	S633N	633	Missense	distal	6	no	31.212	30.893	EPSD	COSMIC	19.113	Down-regulation
TK_Abl_ABL2_Y	P10636	MAPT	P42684	ABL2	Y627	S633I	633	Missense	distal	6	no	31.212	30.803	EPSD	COSMIC	19.113	Down-regulation
TK_Abl_ABL2_Y	P10636	MAPT	P42684	ABL2	Y711	G706R	706	Missense	distal	-5	no	32.075	30.326	EPSD	COSMIC	19.113	Down-regulation
TK_Abl_ABL2_Y	P10636	MAPT	P42684	ABL2	Y711	V710M	710	Missense	proximal	-1	no	32.075	24.419	EPSD	COSMIC	19.113	Down-regulation
TK_Abl_ABL2_Y	P10636	MAPT	P42684	ABL2	Y711	E708K	708	Missense	distal	-3	no	32.075	32.031	EPSD	COSMIC	19.113	Down-regulation
TK_Abl_ABL2_Y	P10636	MAPT	P42684	ABL2	Y711	V710A	710	Missense	proximal	-1	no	32.075	28.423	EPSD	COSMIC	19.113	Down-regulation
TK_Abl_ABL2_Y	O14818	PSMA7	P42684	ABL2	Y153	A158T	158	Missense	distal	5	no	35.748	35.873	PhosphoSitePlus	COSMIC	19.113	Up-regulation
TK_Abl_ABL2_Y	O14818	PSMA7	P42684	ABL2	Y153	A155V	155	Missense	proximal	2	no	35.748	35.709	PhosphoSitePlus	COSMIC	19.113	Down-regulation
TK_Abl_ABL2_Y	O14818	PSMA7	P42684	ABL2	Y153	T147S	147	Missense	distal	-6	no	35.748	35.993	PhosphoSitePlus	COSMIC	19.113	Up-regulation
TK_Abl_ABL2_Y	O14818	PSMA7	P42684	ABL2	Y153	Q146H	146	Missense	distal	-7	no	35.748	35.520	PhosphoSitePlus	COSMIC	19.113	Down-regulation
TK_Abl_ABL2_Y	O14818	PSMA7	P42684	ABL2	Y153	K157N	157	Missense	distal	4	no	35.748	35.844	PhosphoSitePlus	COSMIC	19.113	Up-regulation
TK_Abl_ABL2_Y	P09619	PDGFRB	P42684	ABL2	Y581	P584S	584	Missense	distal	3	no	19.741	8.651	EPSD	COSMIC	19.113	Loss
TK_Abl_ABL2_Y	P09619	PDGFRB	P42684	ABL2	Y581	S574F	574	Missense	distal	-7	no	19.741	11.417	EPSD	COSMIC	19.113	Loss
TK_Abl_ABL2_Y	P09619	PDGFRB	P42684	ABL2	Y581	D583E	583	Missense	proximal	2	no	19.741	19.806	EPSD	COSMIC	19.113	Up-regulation
TK_Abl_ABL2_Y	P09619	PDGFRB	P42684	ABL2	Y686	G687K	687	Missense	proximal	1	no	32.293	30.804	PhosphoSitePlus	COSMIC	19.113	Down-regulation
TK_Abl_ABL2_Y	P09619	PDGFRB	P42684	ABL2	Y771	N770S	770	Missense	proximal	-1	no	20.077	17.412	EPSD	COSMIC	19.113	Loss
TK_Abl_ABL2_Y	P09619	PDGFRB	P42684	ABL2	Y771	E767D	767	Missense	distal	-4	no	20.077	19.590	EPSD	COSMIC	19.113	Down-regulation
TK_Abl_ABL2_Y	P09619	PDGFRB	P42684	ABL2	Y771	M772I	772	Missense	proximal	1	no	20.077	21.340	EPSD	COSMIC;GDSC;CCLE	19.113	Up-regulation
TK_Abl_ABL2_Y	P09619	PDGFRB	P42684	ABL2	Y771	M772V	772	Missense	proximal	1	no	20.077	19.678	EPSD	COSMIC	19.113	Down-regulation
TK_Abl_ABL2_Y	P09619	PDGFRB	P42684	ABL2	Y934	E932K	932	Missense	proximal	-2	no	26.698	26.825	EPSD	COSMIC	19.113	Up-regulation
TK_Abl_ABL2_Y	P09619	PDGFRB	P42684	ABL2	Y934	A929T	929	Missense	distal	-5	no	26.698	26.482	EPSD	COSMIC	19.113	Down-regulation
TK_Abl_ABL2_Y	P09619	PDGFRB	P42684	ABL2	Y970	E964K	964	Missense	distal	-6	no	28.921	29.198	EPSD	COSMIC;GDSC	19.113	Up-regulation
TK_Abl_ABL2_Y	P09619	PDGFRB	P42684	ABL2	Y970	G963D	963	Missense	distal	-7	no	28.921	29.265	EPSD	COSMIC	19.113	Up-regulation
TK_Abl_ABL2_Y	P09619	PDGFRB	P42684	ABL2	Y970	K967Q	967	Missense	distal	-3	no	28.921	28.945	EPSD	COSMIC	19.113	Up-regulation
TK_Abl_ABL2_Y	P09619	PDGFRB	P42684	ABL2	Y970	V973G	973	Missense	distal	3	no	28.921	23.277	EPSD	COSMIC	19.113	Down-regulation
TK_Abl_ABL2_Y	P09619	PDGFRB	P42684	ABL2	Y1009	L1002R	1002	Missense	distal	-7	no	13.443	21.130	EPSD	COSMIC	19.113	Gain
TK_Abl_ABL2_Y	O15304	SIVA1	P42684	ABL2	Y34	E40K	40	Missense	distal	6	no	32.693	32.523	PhosphoSitePlus	COSMIC	19.113	Down-regulation
TKL_LISK_LIMK_LIMK1_ST	P60981	DSTN	P53667	LIMK1	S3	E10Q	10	Missense	distal	7	no	3.818	3.816	PhosphoSitePlus	COSMIC	-0.776	Down-regulation
TK_Src_SrcB_HCK_Y	P00519	ABL1	P08631	HCK	Y70	G76E	76	Missense	distal	6	no	11.596	11.408	EPSD;PhosphoSitePlus	COSMIC	7.597	Down-regulation
TK_Src_SrcB_HCK_Y	P00519	ABL1	P08631	HCK	Y70	D77E	77	Missense	distal	7	no	11.596	11.660	EPSD;PhosphoSitePlus	COSMIC	7.597	Up-regulation
TK_Src_SrcB_HCK_Y	P00519	ABL1	P08631	HCK	Y70	S75G	75	Missense	distal	5	no	11.596	11.374	EPSD;PhosphoSitePlus	COSMIC	7.597	Down-regulation
TK_Src_SrcB_HCK_Y	P00519	ABL1	P08631	HCK	Y70	V67I	67	Missense	distal	-3	no	11.596	10.222	EPSD;PhosphoSitePlus	COSMIC	7.597	Down-regulation
TK_Src_SrcB_HCK_Y	P00519	ABL1	P08631	HCK	Y115	G109V	109	Missense	distal	-6	no	11.227	11.634	EPSD;PhosphoSitePlus	COSMIC	7.597	Up-regulation
TK_Src_SrcB_HCK_Y	P00519	ABL1	P08631	HCK	Y128	K124N	124	Missense	distal	-4	no	11.768	11.771	EPSD;PhosphoSitePlus	COSMIC	7.597	Up-regulation
TK_Src_SrcB_HCK_Y	P00519	ABL1	P08631	HCK	Y128	P131L	131	Missense	distal	3	no	11.768	11.409	EPSD;PhosphoSitePlus	COSMIC	7.597	Down-regulation
TK_Src_SrcB_HCK_Y	P00519	ABL1	P08631	HCK	Y128	R134H	134	Missense	distal	6	no	11.768	11.196	EPSD;PhosphoSitePlus	COSMIC	7.597	Down-regulation
TK_Src_SrcB_HCK_Y	P00519	ABL1	P08631	HCK	Y139	G144E	144	Missense	distal	5	no	11.438	11.455	EPSD;PhosphoSitePlus	COSMIC	7.597	Up-regulation
TK_Src_SrcB_HCK_Y	P00519	ABL1	P08631	HCK	Y139	A137S	137	Missense	proximal	-2	no	11.438	11.513	EPSD;PhosphoSitePlus	COSMIC	7.597	Up-regulation
TK_Src_SrcB_HCK_Y	P00519	ABL1	P08631	HCK	Y139	R134H	134	Missense	distal	-5	no	11.438	11.429	EPSD;PhosphoSitePlus	COSMIC	7.597	Down-regulation
TK_Src_SrcB_HCK_Y	P00519	ABL1	P08631	HCK	Y172	R166K	166	Missense	distal	-6	no	10.715	10.656	EPSD;PhosphoSitePlus	COSMIC;CCLE	7.597	Down-regulation
TK_Src_SrcB_HCK_Y	P00519	ABL1	P08631	HCK	Y172	Y167H	167	Missense	distal	-5	no	10.715	10.668	EPSD;PhosphoSitePlus	COSMIC	7.597	Down-regulation
TK_Src_SrcB_HCK_Y	P00519	ABL1	P08631	HCK	Y185	R191C	191	Missense	distal	6	no	10.695	11.727	EPSD;PhosphoSitePlus	COSMIC	7.597	Up-regulation
TK_Src_SrcB_HCK_Y	P00519	ABL1	P08631	HCK	Y185	S187F	187	Missense	proximal	2	no	10.695	10.186	EPSD;PhosphoSitePlus	COSMIC	7.597	Down-regulation
TK_Src_SrcB_HCK_Y	P00519	ABL1	P08631	HCK	Y185	L184R	184	Missense	proximal	-1	no	10.695	10.733	EPSD;PhosphoSitePlus	COSMIC	7.597	Up-regulation
TK_Src_SrcB_HCK_Y	P00519	ABL1	P08631	HCK	Y215	R220H	220	Missense	distal	5	no	9.755	10.270	EPSD;PhosphoSitePlus	COSMIC	7.597	Up-regulation
TK_Src_SrcB_HCK_Y	P00519	ABL1	P08631	HCK	Y215	P218S	218	Missense	distal	3	no	9.755	10.738	EPSD;PhosphoSitePlus	COSMIC	7.597	Up-regulation
TK_Src_SrcB_HCK_Y	P00519	ABL1	P08631	HCK	Y215	T212R	212	Missense	distal	-3	no	9.755	7.740	EPSD;PhosphoSitePlus	COSMIC	7.597	Down-regulation
TK_Src_SrcB_HCK_Y	P00519	ABL1	P08631	HCK	Y226	R220H	220	Missense	distal	-6	no	8.852	8.401	EPSD;PhosphoSitePlus	COSMIC	7.597	Down-regulation
TK_Src_SrcB_HCK_Y	P00519	ABL1	P08631	HCK	Y226	N231S	231	Missense	distal	5	no	8.852	8.966	EPSD;PhosphoSitePlus	COSMIC	7.597	Up-regulation
TK_Src_SrcB_HCK_Y	P00519	ABL1	P08631	HCK	Y226	G227S	227	Missense	proximal	1	no	8.852	8.894	EPSD;PhosphoSitePlus	COSMIC	7.597	Up-regulation
TK_Src_SrcB_HCK_Y	P00519	ABL1	P08631	HCK	Y226	N231K	231	Missense	distal	5	no	8.852	8.774	EPSD;PhosphoSitePlus	COSMIC	7.597	Down-regulation
TK_Src_SrcB_HCK_Y	P00519	ABL1	P08631	HCK	Y393	R386Q	386	Missense	distal	-7	no	12.301	12.028	PhosphoSitePlus;EPSD	COSMIC	7.597	Down-regulation
TK_Src_SrcB_HCK_Y	P00519	ABL1	P08631	HCK	Y393	A397P	397	Missense	distal	4	no	12.301	10.798	PhosphoSitePlus;EPSD	COSMIC	7.597	Down-regulation
TK_Src_SrcB_HCK_Y	P00519	ABL1	P08631	HCK	Y393	H396R	396	Missense	distal	3	no	12.301	12.420	PhosphoSitePlus;EPSD	COSMIC	7.597	Up-regulation
TK_Src_SrcB_HCK_Y	P00519	ABL1	P08631	HCK	Y393	L387M	387	Missense	distal	-6	no	12.301	11.778	PhosphoSitePlus;EPSD	COSMIC	7.597	Down-regulation
TK_Src_SrcB_HCK_Y	P00519	ABL1	P08631	HCK	Y393	M388L	388	Missense	distal	-5	no	12.301	12.247	PhosphoSitePlus;EPSD	COSMIC	7.597	Down-regulation
TK_Src_SrcB_HCK_Y	P00519	ABL1	P08631	HCK	Y393	G398R	398	Missense	distal	5	no	12.301	11.830	PhosphoSitePlus;EPSD	COSMIC	7.597	Down-regulation
TK_Src_SrcB_HCK_Y	P00519	ABL1	P08631	HCK	Y393	A399T	399	Missense	distal	6	no	12.301	12.465	PhosphoSitePlus;EPSD	COSMIC	7.597	Up-regulation
TK_Src_SrcB_HCK_Y	P00519	ABL1	P08631	HCK	Y393	T389A	389	Missense	distal	-4	no	12.301	12.370	PhosphoSitePlus;EPSD	COSMIC	7.597	Up-regulation
TK_Src_SrcB_HCK_Y	P00519	ABL1	P08631	HCK	Y393	K400E	400	Missense	distal	7	no	12.301	12.440	PhosphoSitePlus;EPSD	COSMIC	7.597	Up-regulation
TK_Src_SrcB_HCK_Y	P00519	ABL1	P08631	HCK	Y393	T394A	394	Missense	proximal	1	no	12.301	12.360	PhosphoSitePlus;EPSD	COSMIC	7.597	Up-regulation
TK_Src_SrcB_HCK_Y	P00519	ABL1	P08631	HCK	Y393	H396P	396	Missense	distal	3	no	12.301	12.455	PhosphoSitePlus;EPSD	COSMIC	7.597	Up-regulation
TK_Src_SrcB_HCK_Y	P00519	ABL1	P08631	HCK	Y393	D391N	391	Missense	proximal	-2	no	12.301	12.094	PhosphoSitePlus;EPSD	COSMIC	7.597	Down-regulation
TK_Src_SrcB_HCK_Y	P00519	ABL1	P08631	HCK	Y393	L387F	387	Missense	distal	-6	no	12.301	11.452	PhosphoSitePlus;EPSD	COSMIC	7.597	Down-regulation
TK_Src_SrcB_HCK_Y	P00519	ABL1	P08631	HCK	Y393	H396Y	396	Missense	distal	3	no	12.301	10.918	PhosphoSitePlus;EPSD	COSMIC	7.597	Down-regulation
TK_Src_SrcB_HCK_Y	P00519	ABL1	P08631	HCK	Y393	G390W	390	Missense	distal	-3	no	12.301	9.167	PhosphoSitePlus;EPSD	COSMIC	7.597	Down-regulation
TK_Src_SrcB_HCK_Y	P11274	BCR	P08631	HCK	Y177	E181D	181	Missense	distal	4	no	11.230	10.596	PhosphoSitePlus	COSMIC	7.597	Down-regulation
TK_Src_SrcB_HCK_Y	Q92556	ELMO1	P08631	HCK	Y18	P19L	19	Missense	proximal	1	no	10.836	10.877	EPSD;PhosphoSitePlus	COSMIC	7.597	Up-regulation
TK_Src_SrcB_HCK_Y	Q92556	ELMO1	P08631	HCK	Y216	V209M	209	Missense	distal	-7	no	10.924	9.968	EPSD;PhosphoSitePlus	COSMIC	7.597	Down-regulation
TK_Src_SrcB_HCK_Y	Q92556	ELMO1	P08631	HCK	Y216	A220G	220	Missense	distal	4	no	10.924	9.171	EPSD;PhosphoSitePlus	COSMIC;CCLE	7.597	Down-regulation
TK_Src_SrcB_HCK_Y	Q92556	ELMO1	P08631	HCK	Y395	Y395F	395	Missense	central	0	yes	11.625	0.000	EPSD;PhosphoSitePlus	COSMIC	7.597	Loss
TK_Src_SrcB_HCK_Y	Q92556	ELMO1	P08631	HCK	Y395	Y395N	395	Missense	central	0	yes	11.625	0.000	EPSD;PhosphoSitePlus	COSMIC	7.597	Loss
TK_Src_SrcB_HCK_Y	P08631	HCK	P08631	HCK	Y51	T56K	56	Missense	distal	5	no	11.142	11.001	EPSD	COSMIC	7.597	Down-regulation
TK_Src_SrcB_HCK_Y	P08631	HCK	P08631	HCK	Y209	P212L	212	Missense	distal	3	no	10.258	9.899	EPSD	COSMIC	7.597	Down-regulation
TK_Src_SrcB_HCK_Y	P08631	HCK	P08631	HCK	Y209	N205H	205	Missense	distal	-4	no	10.258	10.282	EPSD	COSMIC	7.597	Up-regulation
TK_Src_SrcB_HCK_Y	P08631	HCK	P08631	HCK	Y209	D204H	204	Missense	distal	-5	no	10.258	10.232	EPSD	COSMIC	7.597	Down-regulation
TK_Src_SrcB_HCK_Y	P08631	HCK	P08631	HCK	Y209	R213G	213	Missense	distal	4	no	10.258	9.564	EPSD	COSMIC	7.597	Down-regulation
TK_Src_SrcB_HCK_Y	P08631	HCK	P08631	HCK	Y209	D204Y	204	Missense	distal	-5	no	10.258	10.279	EPSD	COSMIC	7.597	Up-regulation
TK_Src_SrcB_HCK_Y	P08631	HCK	P08631	HCK	Y209	G207R	207	Missense	proximal	-2	no	10.258	9.813	EPSD	COSMIC	7.597	Down-regulation
TK_Src_SrcB_HCK_Y	P08631	HCK	P08631	HCK	Y411	V405A	405	Missense	distal	-6	no	11.136	12.038	PhosphoSitePlus;EPSD	COSMIC	7.597	Up-regulation
TK_Src_SrcB_HCK_Y	P08631	HCK	P08631	HCK	Y411	E410K	410	Missense	proximal	-1	no	11.136	11.133	PhosphoSitePlus;EPSD	COSMIC	7.597	Down-regulation
TK_Src_SrcB_HCK_Y	P08631	HCK	P08631	HCK	Y411	D408G	408	Missense	distal	-3	no	11.136	11.957	PhosphoSitePlus;EPSD	COSMIC	7.597	Up-regulation
TK_Src_SrcB_HCK_Y	P08631	HCK	P08631	HCK	Y411	T412K	412	Missense	proximal	1	no	11.136	11.154	PhosphoSitePlus;EPSD	COSMIC	7.597	Up-regulation
TK_Src_SrcB_HCK_Y	P08631	HCK	P08631	HCK	Y411	G416R	416	Missense	distal	5	no	11.136	10.664	PhosphoSitePlus;EPSD	COSMIC	7.597	Down-regulation
TK_Src_SrcB_HCK_Y	P08631	HCK	P08631	HCK	Y411	E415K	415	Missense	distal	4	no	11.136	11.661	PhosphoSitePlus;EPSD	COSMIC	7.597	Up-regulation
TK_Src_SrcB_HCK_Y	P08631	HCK	P08631	HCK	Y411	N409K	409	Missense	proximal	-2	no	11.136	11.301	PhosphoSitePlus;EPSD	COSMIC	7.597	Up-regulation
TK_Src_SrcB_HCK_Y	P42229	STAT5A	P08631	HCK	Y694	A688D	688	Missense	distal	-6	no	11.334	10.252	PhosphoSitePlus	COSMIC	7.597	Down-regulation
TK_Src_SrcB_HCK_Y	Q13444	ADAM15	P08631	HCK	Y715	A713V	713	Missense	proximal	-2	no	11.829	11.007	PhosphoSitePlus	COSMIC;GDSC;CCLE	7.597	Down-regulation
TK_Src_SrcB_HCK_Y	Q13444	ADAM15	P08631	HCK	Y715	S714I	714	Missense	proximal	-1	no	11.829	11.835	PhosphoSitePlus	COSMIC	7.597	Up-regulation
TK_Src_SrcB_HCK_Y	Q13444	ADAM15	P08631	HCK	Y715	G712S	712	Missense	distal	-3	no	11.829	9.959	PhosphoSitePlus	COSMIC	7.597	Down-regulation
TK_Src_SrcB_HCK_Y	Q13444	ADAM15	P08631	HCK	Y715	Y717F	717	Missense	proximal	2	no	11.829	11.742	PhosphoSitePlus	COSMIC	7.597	Down-regulation
TK_Src_SrcB_HCK_Y	Q13444	ADAM15	P08631	HCK	Y735	T732N	732	Missense	distal	-3	no	10.220	10.260	EPSD	COSMIC	7.597	Up-regulation
TK_Src_SrcB_HCK_Y	Q13444	ADAM15	P08631	HCK	Y735	T732P	732	Missense	distal	-3	no	10.220	9.483	EPSD	COSMIC;GDSC	7.597	Down-regulation
TK_Src_SrcB_HCK_Y	Q13444	ADAM15	P08631	HCK	Y735	G741C	741	Missense	distal	6	no	10.220	11.023	EPSD	COSMIC	7.597	Up-regulation
TK_Src_SrcB_HCK_Y	P51692	STAT5B	P08631	HCK	Y699	I704L	704	Missense	distal	5	no	11.353	11.588	PhosphoSitePlus	COSMIC	7.597	Up-regulation
TK_Src_SrcB_HCK_Y	P51692	STAT5B	P08631	HCK	Y699	Q706L	706	Missense	distal	7	no	11.353	11.261	PhosphoSitePlus	COSMIC	7.597	Down-regulation
TK_Src_SrcB_HCK_Y	P51692	STAT5B	P08631	HCK	Y699	V700M	700	Missense	proximal	1	no	11.353	11.343	PhosphoSitePlus	COSMIC	7.597	Down-regulation
TK_Src_SrcB_HCK_Y	P51692	STAT5B	P08631	HCK	Y699	K705N	705	Missense	distal	6	no	11.353	12.172	PhosphoSitePlus	COSMIC	7.597	Up-regulation
TK_Src_SrcB_HCK_Y	P51692	STAT5B	P08631	HCK	Y699	G698E	698	Missense	proximal	-1	no	11.353	11.334	PhosphoSitePlus	COSMIC	7.597	Down-regulation
TK_Src_SrcB_HCK_Y	P51692	STAT5B	P08631	HCK	Y699	V696L	696	Missense	distal	-3	no	11.353	9.848	PhosphoSitePlus	COSMIC	7.597	Down-regulation
TK_Src_SrcB_HCK_Y	Q13905	RAPGEF1	P08631	HCK	Y504	A505G	505	Missense	proximal	1	no	10.996	10.937	PhosphoSitePlus	COSMIC	7.597	Down-regulation
TK_Src_SrcB_HCK_Y	Q13905	RAPGEF1	P08631	HCK	Y504	A509V	509	Missense	distal	5	no	10.996	10.405	PhosphoSitePlus	COSMIC	7.597	Down-regulation
TK_Src_SrcB_HCK_Y	Q13905	RAPGEF1	P08631	HCK	Y504	P498T	498	Missense	distal	-6	no	10.996	11.961	PhosphoSitePlus	COSMIC	7.597	Up-regulation
TK_Src_SrcB_HCK_Y	Q13905	RAPGEF1	P08631	HCK	Y504	A505T	505	Missense	proximal	1	no	10.996	10.936	PhosphoSitePlus	COSMIC	7.597	Down-regulation
TK_Src_SrcB_HCK_Y	Q13905	RAPGEF1	P08631	HCK	Y504	V502I	502	Missense	proximal	-2	no	10.996	11.076	PhosphoSitePlus	COSMIC	7.597	Up-regulation
TK_Src_SrcB_HCK_Y	Q13905	RAPGEF1	P08631	HCK	Y504	A505V	505	Missense	proximal	1	no	10.996	10.912	PhosphoSitePlus	COSMIC	7.597	Down-regulation
TK_Src_SrcB_HCK_Y	Q13905	RAPGEF1	P08631	HCK	Y504	L511P	511	Missense	distal	7	no	10.996	11.010	PhosphoSitePlus	COSMIC	7.597	Up-regulation
TK_Src_SrcB_HCK_Y	O15350	TP73	P08631	HCK	Y28	D30A	30	Missense	proximal	2	no	10.670	11.363	PhosphoSitePlus	COSMIC	7.597	Up-regulation
TK_Src_SrcB_HCK_Y	O15350	TP73	P08631	HCK	Y28	S26L	26	Missense	proximal	-2	no	10.670	9.717	PhosphoSitePlus	COSMIC	7.597	Down-regulation
TK_Src_SrcB_HCK_Y	Q9UHD2	TBK1	P08631	HCK	Y354	S347Y	347	Missense	distal	-7	no	10.303	7.189	PhosphoSitePlus;EPSD	COSMIC	7.597	Loss
TK_Src_SrcB_HCK_Y	Q9UHD2	TBK1	P08631	HCK	Y354	R357Q	357	Missense	distal	3	no	10.303	10.325	PhosphoSitePlus;EPSD	COSMIC	7.597	Up-regulation
TK_Src_SrcB_HCK_Y	Q9UHD2	TBK1	P08631	HCK	Y394	S398F	398	Missense	distal	4	no	12.008	9.935	EPSD;PhosphoSitePlus	COSMIC	7.597	Down-regulation
TKL_MLK_MLK_MAP3K11_ST	Q16584	MAP3K11	Q16584	MAP3K11	S21	S19N	19	Missense	proximal	-2	no	2.731	2.912	EPSD	COSMIC	1.264	Up-regulation
TKL_MLK_MLK_MAP3K11_ST	Q16584	MAP3K11	Q16584	MAP3K11	T277	A283T	283	Missense	distal	6	no	4.223	4.116	EPSD;PhosphoSitePlus	COSMIC	1.264	Down-regulation
TKL_MLK_MLK_MAP3K11_ST	Q16584	MAP3K11	Q16584	MAP3K11	T277	R272P	272	Missense	distal	-5	no	4.223	4.222	EPSD;PhosphoSitePlus	COSMIC	1.264	Down-regulation
TKL_MLK_MLK_MAP3K11_ST	Q16584	MAP3K11	Q16584	MAP3K11	T277	R272Q	272	Missense	distal	-5	no	4.223	4.222	EPSD;PhosphoSitePlus	COSMIC	1.264	Down-regulation
TKL_MLK_MLK_MAP3K11_ST	Q16584	MAP3K11	Q16584	MAP3K11	S281	A283T	283	Missense	proximal	2	no	4.392	4.356	PhosphoSitePlus;EPSD	COSMIC	1.264	Down-regulation
TKL_MLK_MLK_MAP3K11_ST	Q16584	MAP3K11	Q16584	MAP3K11	S770	R773H	773	Missense	distal	3	no	1.179	1.401	EPSD	COSMIC	1.264	Gain
TKL_MLK_MLK_MAP3K11_ST	P46734	MAP2K3	Q16584	MAP3K11	S31	N37S	37	Missense	distal	6	no	1.101	1.313	EPSD	COSMIC	1.264	Gain
TKL_MLK_MLK_MAP3K11_ST	P46734	MAP2K3	Q16584	MAP3K11	S218	L215W	215	Missense	distal	-3	no	4.316	4.268	PhosphoSitePlus;EPSD	COSMIC	1.264	Down-regulation
TKL_MLK_MLK_MAP3K11_ST	P46734	MAP2K3	Q16584	MAP3K11	S218	T222M	222	Missense	distal	4	no	4.316	4.080	PhosphoSitePlus;EPSD	COSMIC	1.264	Down-regulation
TKL_MLK_MLK_MAP3K11_ST	P46734	MAP2K3	Q16584	MAP3K11	S218	L215V	215	Missense	distal	-3	no	4.316	4.374	PhosphoSitePlus;EPSD	COSMIC;GDSC;CCLE	1.264	Up-regulation
TKL_MLK_MLK_MAP3K11_ST	P46734	MAP2K3	Q16584	MAP3K11	T222	L215W	215	Missense	distal	-7	no	4.657	4.670	EPSD;PhosphoSitePlus	COSMIC	1.264	Up-regulation
TKL_MLK_MLK_MAP3K11_ST	P46734	MAP2K3	Q16584	MAP3K11	T222	T222M	222	Missense	central	0	yes	4.657	0.000	EPSD;PhosphoSitePlus	COSMIC	1.264	Loss
TKL_MLK_MLK_MAP3K11_ST	P46734	MAP2K3	Q16584	MAP3K11	T222	K228Q	228	Missense	distal	6	no	4.657	4.658	EPSD;PhosphoSitePlus	COSMIC	1.264	Up-regulation
TKL_MLK_MLK_MAP3K11_ST	P46734	MAP2K3	Q16584	MAP3K11	T222	G226D	226	Missense	distal	4	no	4.657	4.713	EPSD;PhosphoSitePlus	COSMIC;GDSC;CCLE	1.264	Up-regulation
TKL_MLK_MLK_MAP3K11_ST	P46734	MAP2K3	Q16584	MAP3K11	T222	P229H	229	Missense	distal	7	no	4.657	4.929	EPSD;PhosphoSitePlus	COSMIC;GDSC;CCLE	1.264	Up-regulation
TKL_MLK_MLK_MAP3K11_ST	P46734	MAP2K3	Q16584	MAP3K11	T222	G226S	226	Missense	distal	4	no	4.657	4.794	EPSD;PhosphoSitePlus	COSMIC;GDSC	1.264	Up-regulation
TKL_MLK_MLK_MAP3K11_ST	P46734	MAP2K3	Q16584	MAP3K11	T222	L215V	215	Missense	distal	-7	no	4.657	4.673	EPSD;PhosphoSitePlus	COSMIC;GDSC;CCLE	1.264	Up-regulation
TKL_MLK_MLK_MAP3K11_ST	Q13526	PIN1	Q16584	MAP3K11	S38	Q33K	33	Missense	distal	-5	no	1.363	1.362	EPSD	COSMIC	1.264	Down-regulation
TKL_MLK_MLK_MAP3K11_ST	Q13526	PIN1	Q16584	MAP3K11	S38	S42I	42	Missense	distal	4	no	1.363	1.005	EPSD	COSMIC	1.264	Loss
TKL_MLK_MLK_MAP3K11_ST	Q13526	PIN1	Q16584	MAP3K11	S138	P133L	133	Missense	distal	-5	no	3.911	3.914	PhosphoSitePlus	COSMIC	1.264	Up-regulation
TKL_MLK_MLK_MAP3K11_ST	Q13526	PIN1	Q16584	MAP3K11	S147	P149S	149	Missense	proximal	2	no	1.655	1.689	EPSD	COSMIC	1.264	Up-regulation
TKL_MLK_MLK_MAP3K11_ST	Q13526	PIN1	Q16584	MAP3K11	S147	T152M	152	Missense	distal	5	no	1.655	1.652	EPSD	COSMIC	1.264	Down-regulation
TKL_MLK_MLK_MAP3K11_ST	Q13526	PIN1	Q16584	MAP3K11	T152	P149S	149	Missense	distal	-3	no	1.711	1.609	EPSD	COSMIC	1.264	Down-regulation
TKL_MLK_MLK_MAP3K11_ST	Q13526	PIN1	Q16584	MAP3K11	T152	T152M	152	Missense	central	0	yes	1.711	0.000	EPSD	COSMIC	1.264	Loss
TKL_MLK_MLK_MAP3K11_ST	Q13131	PRKAA1	Q16584	MAP3K11	S65	G70A	70	Missense	distal	5	no	1.690	1.670	EPSD	COSMIC	1.264	Down-regulation
TKL_MLK_MLK_MAP3K11_ST	Q13131	PRKAA1	Q16584	MAP3K11	S65	R64W	64	Missense	proximal	-1	no	1.690	1.531	EPSD	COSMIC	1.264	Down-regulation
TKL_MLK_MLK_MAP3K11_ST	Q13131	PRKAA1	Q16584	MAP3K11	S65	R64C	64	Missense	proximal	-1	no	1.690	1.606	EPSD	COSMIC	1.264	Down-regulation
TKL_MLK_MLK_MAP3K11_ST	Q13131	PRKAA1	Q16584	MAP3K11	S498	V497A	497	Missense	proximal	-1	no	1.517	1.914	EPSD	COSMIC	1.264	Up-regulation
TKL_MLK_MLK_MAP3K11_ST	Q13131	PRKAA1	Q16584	MAP3K11	S498	R501G	501	Missense	distal	3	no	1.517	1.736	EPSD	COSMIC	1.264	Up-regulation
TKL_MLK_MLK_MAP3K11_ST	Q13131	PRKAA1	Q16584	MAP3K11	S498	R505K	505	Missense	distal	7	no	1.517	1.393	EPSD	COSMIC	1.264	Down-regulation
TKL_MLK_MLK_MAP3K11_ST	Q13131	PRKAA1	Q16584	MAP3K11	S498	R505G	505	Missense	distal	7	no	1.517	1.742	EPSD	COSMIC	1.264	Up-regulation
TKL_MLK_MLK_MAP3K11_ST	P45985	MAP2K4	Q16584	MAP3K11	S12	S16R	16	Missense	distal	4	no	1.331	1.064	EPSD	COSMIC	1.264	Loss
TKL_MLK_MLK_MAP3K11_ST	P45985	MAP2K4	Q16584	MAP3K11	S12	G9S	9	Missense	distal	-3	no	1.331	1.358	EPSD	COSMIC;CCLE	1.264	Up-regulation
TKL_MLK_MLK_MAP3K11_ST	P45985	MAP2K4	Q16584	MAP3K11	S12	S18R	18	Missense	distal	6	no	1.331	1.191	EPSD	COSMIC	1.264	Loss
TKL_MLK_MLK_MAP3K11_ST	P45985	MAP2K4	Q16584	MAP3K11	S12	S18G	18	Missense	distal	6	no	1.331	1.035	EPSD	COSMIC	1.264	Loss
TKL_MLK_MLK_MAP3K11_ST	P45985	MAP2K4	Q16584	MAP3K11	S26	P29L	29	Missense	distal	3	no	0.949	1.270	EPSD	COSMIC	1.264	Gain
TKL_MLK_MLK_MAP3K11_ST	P45985	MAP2K4	Q16584	MAP3K11	S80	E74K	74	Missense	distal	-6	no	1.301	1.396	EPSD	COSMIC	1.264	Up-regulation
TKL_MLK_MLK_MAP3K11_ST	P45985	MAP2K4	Q16584	MAP3K11	S80	R77G	77	Missense	distal	-3	no	1.301	1.286	EPSD	COSMIC	1.264	Down-regulation
TKL_MLK_MLK_MAP3K11_ST	P45985	MAP2K4	Q16584	MAP3K11	S80	G85R	85	Missense	distal	5	no	1.301	1.287	EPSD	COSMIC	1.264	Down-regulation
TKL_MLK_MLK_MAP3K11_ST	P45985	MAP2K4	Q16584	MAP3K11	S90	P91L	91	Missense	proximal	1	no	1.321	1.322	EPSD	COSMIC	1.264	Up-regulation
TKL_MLK_MLK_MAP3K11_ST	P45985	MAP2K4	Q16584	MAP3K11	S90	E92K	92	Missense	proximal	2	no	1.321	1.330	EPSD	COSMIC	1.264	Up-regulation
TKL_MLK_MLK_MAP3K11_ST	P45985	MAP2K4	Q16584	MAP3K11	S90	P91T	91	Missense	proximal	1	no	1.321	1.357	EPSD	COSMIC	1.264	Up-regulation
TKL_MLK_MLK_MAP3K11_ST	P45985	MAP2K4	Q16584	MAP3K11	S90	F97V	97	Missense	distal	7	no	1.321	0.963	EPSD	COSMIC	1.264	Loss
TKL_MLK_MLK_MAP3K11_ST	P45985	MAP2K4	Q16584	MAP3K11	S90	P91H	91	Missense	proximal	1	no	1.321	1.333	EPSD	COSMIC	1.264	Up-regulation
TKL_MLK_MLK_MAP3K11_ST	P45985	MAP2K4	Q16584	MAP3K11	S90	D96V	96	Missense	distal	6	no	1.321	1.002	EPSD	COSMIC	1.264	Loss
TKL_MLK_MLK_MAP3K11_ST	P45985	MAP2K4	Q16584	MAP3K11	S90	W95C	95	Missense	distal	5	no	1.321	1.311	EPSD	COSMIC	1.264	Down-regulation
TKL_MLK_MLK_MAP3K11_ST	P45985	MAP2K4	Q16584	MAP3K11	S90	E92A	92	Missense	proximal	2	no	1.321	1.365	EPSD	COSMIC	1.264	Up-regulation
TKL_MLK_MLK_MAP3K11_ST	P45985	MAP2K4	Q16584	MAP3K11	S90	G85R	85	Missense	distal	-5	no	1.321	1.320	EPSD	COSMIC	1.264	Down-regulation
TKL_MLK_MLK_MAP3K11_ST	P45985	MAP2K4	Q16584	MAP3K11	S257	S251R	251	Missense	distal	-6	no	4.462	4.513	PhosphoSitePlus;EPSD	COSMIC	1.264	Up-regulation
TKL_MLK_MLK_MAP3K11_ST	P45985	MAP2K4	Q16584	MAP3K11	S257	T261R	261	Missense	distal	4	no	4.462	4.224	PhosphoSitePlus;EPSD	COSMIC	1.264	Down-regulation
TKL_MLK_MLK_MAP3K11_ST	P45985	MAP2K4	Q16584	MAP3K11	S257	S251N	251	Missense	distal	-6	no	4.462	4.421	PhosphoSitePlus;EPSD	COSMIC;GDSC;CCLE	1.264	Down-regulation
TKL_MLK_MLK_MAP3K11_ST	P45985	MAP2K4	Q16584	MAP3K11	S257	S257C	257	Missense	central	0	yes	4.462	0.000	PhosphoSitePlus;EPSD	COSMIC	1.264	Loss
TKL_MLK_MLK_MAP3K11_ST	P45985	MAP2K4	Q16584	MAP3K11	S257	D263Y	263	Missense	distal	6	no	4.462	4.322	PhosphoSitePlus;EPSD	COSMIC	1.264	Down-regulation
TKL_MLK_MLK_MAP3K11_ST	P45985	MAP2K4	Q16584	MAP3K11	S257	S257Y	257	Missense	central	0	yes	4.462	0.000	PhosphoSitePlus;EPSD	COSMIC	1.264	Loss
TKL_MLK_MLK_MAP3K11_ST	P45985	MAP2K4	Q16584	MAP3K11	S257	G252R	252	Missense	distal	-5	no	4.462	4.461	PhosphoSitePlus;EPSD	COSMIC	1.264	Down-regulation
TKL_MLK_MLK_MAP3K11_ST	P45985	MAP2K4	Q16584	MAP3K11	S257	S251T	251	Missense	distal	-6	no	4.462	4.379	PhosphoSitePlus;EPSD	COSMIC	1.264	Down-regulation
TKL_MLK_MLK_MAP3K11_ST	P45985	MAP2K4	Q16584	MAP3K11	S257	L254R	254	Missense	distal	-3	no	4.462	4.380	PhosphoSitePlus;EPSD	COSMIC;GDSC;CCLE	1.264	Down-regulation
TKL_MLK_MLK_MAP3K11_ST	P45985	MAP2K4	Q16584	MAP3K11	S257	A259T	259	Missense	proximal	2	no	4.462	4.425	PhosphoSitePlus;EPSD	COSMIC	1.264	Down-regulation
TKL_MLK_MLK_MAP3K11_ST	P45985	MAP2K4	Q16584	MAP3K11	T261	T261R	261	Missense	central	0	yes	4.420	0.000	EPSD;PhosphoSitePlus	COSMIC	1.264	Loss
TKL_MLK_MLK_MAP3K11_ST	P45985	MAP2K4	Q16584	MAP3K11	T261	P268S	268	Missense	distal	7	no	4.420	4.450	EPSD;PhosphoSitePlus	COSMIC	1.264	Up-regulation
TKL_MLK_MLK_MAP3K11_ST	P45985	MAP2K4	Q16584	MAP3K11	T261	S257C	257	Missense	distal	-4	no	4.420	4.408	EPSD;PhosphoSitePlus	COSMIC	1.264	Down-regulation
TKL_MLK_MLK_MAP3K11_ST	P45985	MAP2K4	Q16584	MAP3K11	T261	D263Y	263	Missense	proximal	2	no	4.420	4.385	EPSD;PhosphoSitePlus	COSMIC	1.264	Down-regulation
TKL_MLK_MLK_MAP3K11_ST	P45985	MAP2K4	Q16584	MAP3K11	T261	S257T	257	Missense	distal	-4	no	4.420	4.393	EPSD;PhosphoSitePlus	COSMIC	1.264	Down-regulation
TKL_MLK_MLK_MAP3K11_ST	P45985	MAP2K4	Q16584	MAP3K11	T261	S257Y	257	Missense	distal	-4	no	4.420	4.436	EPSD;PhosphoSitePlus	COSMIC	1.264	Up-regulation
TKL_MLK_MLK_MAP3K11_ST	P45985	MAP2K4	Q16584	MAP3K11	T261	G265D	265	Missense	distal	4	no	4.420	4.476	EPSD;PhosphoSitePlus	COSMIC;GDSC;CCLE	1.264	Up-regulation
TKL_MLK_MLK_MAP3K11_ST	P45985	MAP2K4	Q16584	MAP3K11	T261	L254R	254	Missense	distal	-7	no	4.420	4.431	EPSD;PhosphoSitePlus	COSMIC;GDSC;CCLE	1.264	Up-regulation
TKL_MLK_MLK_MAP3K11_ST	P45985	MAP2K4	Q16584	MAP3K11	T261	R267M	267	Missense	distal	6	no	4.420	4.350	EPSD;PhosphoSitePlus	COSMIC	1.264	Down-regulation
TKL_MLK_MLK_MAP3K11_ST	P45985	MAP2K4	Q16584	MAP3K11	T261	A259T	259	Missense	proximal	-2	no	4.420	4.375	EPSD;PhosphoSitePlus	COSMIC	1.264	Down-regulation
Atypical_PDHK_PDHK_PDK3_ST	P08559	PDHA1	Q15120	PDK3	S130	E133K	133	Missense	distal	3	no	1.889	2.006	EPSD	COSMIC	1.746	Up-regulation
Atypical_PDHK_PDHK_PDK3_ST	P08559	PDHA1	Q15120	PDK3	S130	R127W	127	Missense	distal	-3	no	1.889	1.634	EPSD	COSMIC	1.746	Loss
Atypical_PDHK_PDHK_PDK3_ST	P08559	PDHA1	Q15120	PDK3	S130	R132Q	132	Missense	proximal	2	no	1.889	1.061	EPSD	COSMIC	1.746	Loss
Atypical_PDHK_PDHK_PDK3_ST	P08559	PDHA1	Q15120	PDK3	S130	A136T	136	Missense	distal	6	no	1.889	1.893	EPSD	COSMIC	1.746	Up-regulation
Atypical_PDHK_PDHK_PDK3_ST	P08559	PDHA1	Q15120	PDK3	S130	L135I	135	Missense	distal	5	no	1.889	2.156	EPSD	COSMIC	1.746	Up-regulation
Atypical_PDHK_PDHK_PDK3_ST	P08559	PDHA1	Q15120	PDK3	T286	Y287H	287	Missense	proximal	1	no	1.908	1.136	EPSD	COSMIC	1.746	Loss
Atypical_PDHK_PDHK_PDK3_ST	P08559	PDHA1	Q15120	PDK3	T286	I280N	280	Missense	distal	-6	no	1.908	1.831	EPSD	COSMIC	1.746	Down-regulation
Atypical_PDHK_PDHK_PDK3_ST	P08559	PDHA1	Q15120	PDK3	T286	M282L	282	Missense	distal	-4	no	1.908	1.812	EPSD	COSMIC	1.746	Down-regulation
Atypical_PDHK_PDHK_PDK3_ST	P08559	PDHA1	Q15120	PDK3	T286	R288C	288	Missense	proximal	2	no	1.908	0.887	EPSD	COSMIC	1.746	Loss
Atypical_PDHK_PDHK_PDK3_ST	P08559	PDHA1	Q15120	PDK3	S293	Y287H	287	Missense	distal	-6	no	10.219	9.912	PhosphoSitePlus;EPSD	COSMIC	1.746	Down-regulation
Atypical_PDHK_PDHK_PDK3_ST	P08559	PDHA1	Q15120	PDK3	S293	R288C	288	Missense	distal	-5	no	10.219	9.538	PhosphoSitePlus;EPSD	COSMIC	1.746	Down-regulation
Atypical_PDHK_PDHK_PDK3_ST	P08559	PDHA1	Q15120	PDK3	S295	R302S	302	Missense	distal	7	no	2.543	2.727	EPSD	COSMIC	1.746	Up-regulation
Atypical_PDHK_PDHK_PDK3_ST	P08559	PDHA1	Q15120	PDK3	S295	R288C	288	Missense	distal	-7	no	2.543	2.389	EPSD	COSMIC	1.746	Down-regulation
Atypical_PDHK_PDHK_PDK3_ST	P08559	PDHA1	Q15120	PDK3	S295	R302C	302	Missense	distal	7	no	2.543	2.527	EPSD	COSMIC	1.746	Down-regulation
Atypical_PDHK_PDHK_PDK3_ST	P08559	PDHA1	Q15120	PDK3	S295	R302L	302	Missense	distal	7	no	2.543	2.403	EPSD	COSMIC	1.746	Down-regulation
Atypical_PDHK_PDHK_PDK3_ST	P08559	PDHA1	Q15120	PDK3	S300	R302S	302	Missense	proximal	2	no	9.409	9.038	EPSD;PhosphoSitePlus	COSMIC	1.746	Down-regulation
Atypical_PDHK_PDHK_PDK3_ST	P08559	PDHA1	Q15120	PDK3	S300	R304Q	304	Missense	distal	4	no	9.409	9.417	EPSD;PhosphoSitePlus	COSMIC;GDSC;CCLE	1.746	Up-regulation
Atypical_PDHK_PDHK_PDK3_ST	P08559	PDHA1	Q15120	PDK3	S300	R302C	302	Missense	proximal	2	no	9.409	8.388	EPSD;PhosphoSitePlus	COSMIC	1.746	Down-regulation
Atypical_PDHK_PDHK_PDK3_ST	P08559	PDHA1	Q15120	PDK3	S300	R302L	302	Missense	proximal	2	no	9.409	8.354	EPSD;PhosphoSitePlus	COSMIC	1.746	Down-regulation
Atypical_PDHK_PDHK_PDK3_ST	P29803	PDHA2	Q15120	PDK3	S128	G126R	126	Missense	proximal	-2	no	1.673	2.018	EPSD	COSMIC	1.746	Gain
Atypical_PDHK_PDHK_PDK3_ST	P29803	PDHA2	Q15120	PDK3	S128	L133I	133	Missense	distal	5	no	1.673	1.940	EPSD	COSMIC	1.746	Gain
Atypical_PDHK_PDHK_PDK3_ST	P29803	PDHA2	Q15120	PDK3	T231	A236V	236	Missense	distal	5	no	2.638	2.768	EPSD	COSMIC	1.746	Up-regulation
Atypical_PDHK_PDHK_PDK3_ST	P29803	PDHA2	Q15120	PDK3	S273	C271R	271	Missense	proximal	-2	no	0.729	1.876	EPSD	COSMIC	1.746	Gain
Atypical_PDHK_PDHK_PDK3_ST	P29803	PDHA2	Q15120	PDK3	T284	R286H	286	Missense	proximal	2	no	1.777	0.841	EPSD	COSMIC	1.746	Loss
Atypical_PDHK_PDHK_PDK3_ST	P29803	PDHA2	Q15120	PDK3	T284	M280T	280	Missense	distal	-4	no	1.777	1.741	EPSD	COSMIC	1.746	Loss
Atypical_PDHK_PDHK_PDK3_ST	P29803	PDHA2	Q15120	PDK3	T284	T284I	284	Missense	central	0	yes	1.777	0.000	EPSD	COSMIC	1.746	Loss
Atypical_PDHK_PDHK_PDK3_ST	P29803	PDHA2	Q15120	PDK3	T284	L282R	282	Missense	proximal	-2	no	1.777	3.180	EPSD	COSMIC	1.746	Up-regulation
Atypical_PDHK_PDHK_PDK3_ST	P29803	PDHA2	Q15120	PDK3	T284	T284P	284	Missense	central	0	yes	1.777	0.000	EPSD	COSMIC	1.746	Loss
Atypical_PDHK_PDHK_PDK3_ST	P29803	PDHA2	Q15120	PDK3	T284	P277L	277	Missense	distal	-7	no	1.777	1.713	EPSD	COSMIC	1.746	Loss
Atypical_PDHK_PDHK_PDK3_ST	P29803	PDHA2	Q15120	PDK3	S291	R286H	286	Missense	distal	-5	no	10.124	9.468	EPSD;PhosphoSitePlus	COSMIC	1.746	Down-regulation
Atypical_PDHK_PDHK_PDK3_ST	P29803	PDHA2	Q15120	PDK3	S291	T284I	284	Missense	distal	-7	no	10.124	10.021	EPSD;PhosphoSitePlus	COSMIC	1.746	Down-regulation
Atypical_PDHK_PDHK_PDK3_ST	P29803	PDHA2	Q15120	PDK3	S291	T284P	284	Missense	distal	-7	no	10.124	10.015	EPSD;PhosphoSitePlus	COSMIC	1.746	Down-regulation
Atypical_PDHK_PDHK_PDK3_ST	P29803	PDHA2	Q15120	PDK3	S291	D294Y	294	Missense	distal	3	no	10.124	10.082	EPSD;PhosphoSitePlus	COSMIC;GDSC;CCLE	1.746	Down-regulation
Atypical_PDHK_PDHK_PDK3_ST	P29803	PDHA2	Q15120	PDK3	S293	R286H	286	Missense	distal	-7	no	2.409	2.260	EPSD	COSMIC	1.746	Down-regulation
Atypical_PDHK_PDHK_PDK3_ST	P29803	PDHA2	Q15120	PDK3	S293	D294Y	294	Missense	proximal	1	no	2.409	3.546	EPSD	COSMIC;GDSC;CCLE	1.746	Up-regulation
Atypical_PDHK_PDHK_PDK3_ST	P29803	PDHA2	Q15120	PDK3	S298	E304K	304	Missense	distal	6	no	9.541	9.537	PhosphoSitePlus;EPSD	COSMIC	1.746	Down-regulation
Atypical_PDHK_PDHK_PDK3_ST	P29803	PDHA2	Q15120	PDK3	S298	D294Y	294	Missense	distal	-4	no	9.541	9.537	PhosphoSitePlus;EPSD	COSMIC;GDSC;CCLE	1.746	Down-regulation
Atypical_PDHK_PDHK_PDK3_ST	P29803	PDHA2	Q15120	PDK3	S310	E307K	307	Missense	distal	-3	no	1.993	1.883	EPSD	COSMIC	1.746	Down-regulation
Atypical_PDHK_PDHK_PDK3_ST	P29803	PDHA2	Q15120	PDK3	S310	I316K	316	Missense	distal	6	no	1.993	1.992	EPSD	COSMIC	1.746	Down-regulation
Atypical_PDHK_PDHK_PDK3_ST	P29803	PDHA2	Q15120	PDK3	S310	E304K	304	Missense	distal	-6	no	1.993	1.951	EPSD	COSMIC	1.746	Down-regulation
AGC_DMPK_ROCK_ROCK2_ST	P19634	SLC9A1	O75116	ROCK2	S18	A24V	24	Missense	distal	6	no	23.187	23.567	EPSD	COSMIC	20.789	Up-regulation
AGC_DMPK_ROCK_ROCK2_ST	P19634	SLC9A1	O75116	ROCK2	T653	D657Y	657	Missense	distal	4	no	28.935	28.792	PhosphoSitePlus	COSMIC	20.789	Down-regulation
AGC_DMPK_ROCK_ROCK2_ST	P19634	SLC9A1	O75116	ROCK2	S703	R700H	700	Missense	distal	-3	no	20.803	9.477	EPSD	COSMIC;GDSC;CCLE	20.789	Loss
AGC_DMPK_ROCK_ROCK2_ST	P19634	SLC9A1	O75116	ROCK2	S766	P772L	772	Missense	distal	6	no	25.432	25.607	EPSD	COSMIC	20.789	Up-regulation
AGC_DMPK_ROCK_ROCK2_ST	P19634	SLC9A1	O75116	ROCK2	S766	P772S	772	Missense	distal	6	no	25.432	24.959	EPSD	COSMIC	20.789	Down-regulation
AGC_DMPK_ROCK_ROCK2_ST	P19634	SLC9A1	O75116	ROCK2	S766	G760E	760	Missense	distal	-6	no	25.432	19.242	EPSD	COSMIC	20.789	Loss
AGC_DMPK_ROCK_ROCK2_ST	P19634	SLC9A1	O75116	ROCK2	S766	D759N	759	Missense	distal	-7	no	25.432	24.894	EPSD	COSMIC	20.789	Down-regulation
AGC_DMPK_ROCK_ROCK2_ST	P56817	BACE1	O75116	ROCK2	T47	E46A	46	Missense	proximal	-1	no	22.784	23.511	EPSD	COSMIC;CCLE	20.789	Up-regulation
AGC_DMPK_ROCK_ROCK2_ST	P56817	BACE1	O75116	ROCK2	S59	F60L	60	Missense	proximal	1	no	23.679	23.735	EPSD	COSMIC	20.789	Up-regulation
AGC_DMPK_ROCK_ROCK2_ST	P56817	BACE1	O75116	ROCK2	S59	R57C	57	Missense	proximal	-2	no	23.679	0.274	EPSD	COSMIC	20.789	Loss
AGC_DMPK_ROCK_ROCK2_ST	P56817	BACE1	O75116	ROCK2	S498	D491H	491	Missense	distal	-7	no	27.416	26.716	PhosphoSitePlus	COSMIC	20.789	Down-regulation
AGC_DMPK_ROCK_ROCK2_ST	Q92673	SORL1	O75116	ROCK2	S732	R726I	726	Missense	distal	-6	no	33.466	29.391	EPSD	COSMIC;GDSC;CCLE	20.789	Down-regulation
AGC_DMPK_ROCK_ROCK2_ST	Q92673	SORL1	O75116	ROCK2	S732	R729Q	729	Missense	distal	-3	no	33.466	22.747	EPSD	COSMIC	20.789	Down-regulation
AGC_DMPK_ROCK_ROCK2_ST	Q92673	SORL1	O75116	ROCK2	S732	K730N	730	Missense	proximal	-2	no	33.466	28.277	EPSD	COSMIC	20.789	Down-regulation
AGC_DMPK_ROCK_ROCK2_ST	Q92673	SORL1	O75116	ROCK2	S732	G738R	738	Missense	distal	6	no	33.466	33.183	EPSD	COSMIC	20.789	Down-regulation
AGC_DMPK_ROCK_ROCK2_ST	Q92673	SORL1	O75116	ROCK2	S1174	G1168S	1168	Missense	distal	-6	no	26.470	24.231	EPSD	COSMIC	20.789	Down-regulation
AGC_DMPK_ROCK_ROCK2_ST	Q92673	SORL1	O75116	ROCK2	S1174	C1177Y	1177	Missense	distal	3	no	26.470	26.850	EPSD	COSMIC	20.789	Up-regulation
AGC_DMPK_ROCK_ROCK2_ST	Q92673	SORL1	O75116	ROCK2	S1174	G1179E	1179	Missense	distal	5	no	26.470	26.515	EPSD	COSMIC	20.789	Up-regulation
AGC_DMPK_ROCK_ROCK2_ST	Q92673	SORL1	O75116	ROCK2	S1174	R1172H	1172	Missense	proximal	-2	no	26.470	17.697	EPSD	COSMIC;GDSC;CCLE	20.789	Loss
AGC_DMPK_ROCK_ROCK2_ST	Q92673	SORL1	O75116	ROCK2	S1174	S1174F	1174	Missense	central	0	yes	26.470	0.000	EPSD	COSMIC	20.789	Loss
AGC_DMPK_ROCK_ROCK2_ST	Q92673	SORL1	O75116	ROCK2	S1174	D1178G	1178	Missense	distal	4	no	26.470	25.699	EPSD	COSMIC	20.789	Down-regulation
AGC_DMPK_ROCK_ROCK2_ST	Q92673	SORL1	O75116	ROCK2	T1612	P1619T	1619	Missense	distal	7	no	20.651	20.925	EPSD	COSMIC	20.789	Gain
AGC_DMPK_ROCK_ROCK2_ST	Q92673	SORL1	O75116	ROCK2	S1987	E1990K	1990	Missense	distal	3	no	24.100	25.360	EPSD	COSMIC	20.789	Up-regulation
AGC_DMPK_ROCK_ROCK2_ST	Q92673	SORL1	O75116	ROCK2	S2179	L2181P	2181	Missense	proximal	2	no	21.926	21.701	EPSD	COSMIC	20.789	Down-regulation
AGC_DMPK_ROCK_ROCK2_ST	Q92673	SORL1	O75116	ROCK2	S2179	A2184T	2184	Missense	distal	5	no	21.926	22.392	EPSD	COSMIC	20.789	Up-regulation
AGC_DMPK_ROCK_ROCK2_ST	Q92673	SORL1	O75116	ROCK2	S2183	L2181P	2181	Missense	proximal	-2	no	18.493	21.812	EPSD	COSMIC	20.789	Gain
AGC_DMPK_ROCK_ROCK2_ST	Q92673	SORL1	O75116	ROCK2	S2206	P2210S	2210	Missense	distal	4	no	31.665	30.847	PhosphoSitePlus	COSMIC	20.789	Down-regulation
AGC_DMPK_ROCK_ROCK2_ST	Q92673	SORL1	O75116	ROCK2	S2206	V2212L	2212	Missense	distal	6	no	31.665	31.405	PhosphoSitePlus	COSMIC	20.789	Down-regulation
AGC_DMPK_ROCK_ROCK2_ST	Q92673	SORL1	O75116	ROCK2	S2206	V2212M	2212	Missense	distal	6	no	31.665	31.283	PhosphoSitePlus	COSMIC	20.789	Down-regulation
AGC_DMPK_ROCK_ROCK2_ST	Q92673	SORL1	O75116	ROCK2	S2206	V2209I	2209	Missense	distal	3	no	31.665	31.391	PhosphoSitePlus	COSMIC	20.789	Down-regulation
AGC_DMPK_ROCK_ROCK2_ST	Q16555	DPYSL2	O75116	ROCK2	T13	D15Y	15	Missense	proximal	2	no	50.561	50.683	EPSD	COSMIC	20.789	Up-regulation
AGC_DMPK_ROCK_ROCK2_ST	Q16555	DPYSL2	O75116	ROCK2	S14	D15Y	15	Missense	proximal	1	no	37.529	37.557	EPSD	COSMIC	20.789	Up-regulation
AGC_DMPK_ROCK_ROCK2_ST	Q16555	DPYSL2	O75116	ROCK2	S85	T84M	84	Missense	proximal	-1	no	27.245	27.196	EPSD	COSMIC	20.789	Down-regulation
AGC_DMPK_ROCK_ROCK2_ST	Q16555	DPYSL2	O75116	ROCK2	T554	R557C	557	Missense	distal	3	no	20.455	21.185	EPSD	COSMIC	20.789	Gain
AGC_DMPK_ROCK_ROCK2_ST	Q16555	DPYSL2	O75116	ROCK2	T554	P561F	561	Missense	distal	7	no	20.455	21.582	EPSD	COSMIC	20.789	Gain
AGC_DMPK_ROCK_ROCK2_ST	Q16555	DPYSL2	O75116	ROCK2	T554	R557H	557	Missense	distal	3	no	20.455	22.239	EPSD	COSMIC	20.789	Gain
AGC_DMPK_ROCK_ROCK2_ST	Q16555	DPYSL2	O75116	ROCK2	T555	N549S	549	Missense	distal	-6	no	39.349	39.713	PhosphoSitePlus	COSMIC	20.789	Up-regulation
AGC_DMPK_ROCK_ROCK2_ST	Q16555	DPYSL2	O75116	ROCK2	T555	P561L	561	Missense	distal	6	no	39.349	39.523	PhosphoSitePlus	COSMIC	20.789	Up-regulation
AGC_DMPK_ROCK_ROCK2_ST	Q16555	DPYSL2	O75116	ROCK2	T555	R557C	557	Missense	proximal	2	no	39.349	39.079	PhosphoSitePlus	COSMIC	20.789	Down-regulation
AGC_DMPK_ROCK_ROCK2_ST	Q16555	DPYSL2	O75116	ROCK2	T555	P561F	561	Missense	distal	6	no	39.349	39.618	PhosphoSitePlus	COSMIC	20.789	Up-regulation
AGC_DMPK_ROCK_ROCK2_ST	Q16555	DPYSL2	O75116	ROCK2	T555	R557H	557	Missense	proximal	2	no	39.349	39.617	PhosphoSitePlus	COSMIC	20.789	Up-regulation
AGC_DMPK_ROCK_ROCK2_ST	P10916	MYL2	O75116	ROCK2	S15	N16Y	16	Missense	proximal	1	no	37.571	37.507	PhosphoSitePlus	COSMIC	20.789	Down-regulation
AGC_DMPK_ROCK_ROCK2_ST	P10916	MYL2	O75116	ROCK2	S15	K8R	8	Missense	distal	-7	no	37.571	37.157	PhosphoSitePlus	COSMIC	20.789	Down-regulation
AGC_DMPK_ROCK_ROCK2_ST	P10916	MYL2	O75116	ROCK2	T98	E96K	96	Missense	proximal	-2	no	17.611	22.182	EPSD	COSMIC	20.789	Gain
AGC_DMPK_ROCK_ROCK2_ST	P10916	MYL2	O75116	ROCK2	T124	A127E	127	Missense	distal	3	no	23.427	21.905	EPSD	COSMIC	20.789	Down-regulation
AGC_DMPK_ROCK_ROCK2_ST	P10916	MYL2	O75116	ROCK2	T124	T124I	124	Missense	central	0	yes	23.427	0.000	EPSD	COSMIC	20.789	Loss
AGC_DMPK_ROCK_ROCK2_ST	P10916	MYL2	O75116	ROCK2	T124	D117N	117	Missense	distal	-7	no	23.427	22.889	EPSD	COSMIC	20.789	Down-regulation
AGC_DMPK_ROCK_ROCK2_ST	P10916	MYL2	O75116	ROCK2	T124	R120W	120	Missense	distal	-4	no	23.427	22.471	EPSD	COSMIC	20.789	Down-regulation
AGC_DMPK_ROCK_ROCK2_ST	P10916	MYL2	O75116	ROCK2	T124	R120L	120	Missense	distal	-4	no	23.427	23.229	EPSD	COSMIC	20.789	Down-regulation
AGC_DMPK_ROCK_ROCK2_ST	O95644	NFATC1	O75116	ROCK2	S241	S237P	237	Missense	distal	-4	no	29.014	29.451	PhosphoSitePlus	COSMIC	20.789	Up-regulation
AGC_DMPK_ROCK_ROCK2_ST	O95644	NFATC1	O75116	ROCK2	S241	R235W	235	Missense	distal	-6	no	29.014	26.859	PhosphoSitePlus	COSMIC	20.789	Down-regulation
AGC_DMPK_ROCK_ROCK2_ST	O95644	NFATC1	O75116	ROCK2	S257	S257F	257	Missense	central	0	yes	20.848	0.000	EPSD	COSMIC	20.789	Loss
AGC_DMPK_ROCK_ROCK2_ST	O95644	NFATC1	O75116	ROCK2	S257	A260T	260	Missense	distal	3	no	20.848	19.476	EPSD	COSMIC	20.789	Loss
AGC_DMPK_ROCK_ROCK2_ST	O95644	NFATC1	O75116	ROCK2	S257	R258I	258	Missense	proximal	1	no	20.848	20.899	EPSD	COSMIC	20.789	Up-regulation
AGC_DMPK_ROCK_ROCK2_ST	O95644	NFATC1	O75116	ROCK2	S257	R255K	255	Missense	proximal	-2	no	20.848	11.895	EPSD	COSMIC	20.789	Loss
AGC_DMPK_ROCK_ROCK2_ST	O95644	NFATC1	O75116	ROCK2	S406	P410L	410	Missense	distal	4	no	22.810	22.329	EPSD	COSMIC	20.789	Down-regulation
AGC_DMPK_ROCK_ROCK2_ST	O95644	NFATC1	O75116	ROCK2	S406	S406F	406	Missense	central	0	yes	22.810	0.000	EPSD	COSMIC;CCLE	20.789	Loss
AGC_DMPK_ROCK_ROCK2_ST	O95644	NFATC1	O75116	ROCK2	S406	P413H	413	Missense	distal	7	no	22.810	22.386	EPSD	COSMIC;CCLE	20.789	Down-regulation
AGC_DMPK_ROCK_ROCK2_ST	O95644	NFATC1	O75116	ROCK2	S503	T505P	505	Missense	proximal	2	no	21.429	21.376	EPSD	COSMIC	20.789	Down-regulation
AGC_DMPK_ROCK_ROCK2_ST	O95644	NFATC1	O75116	ROCK2	S772	A775S	775	Missense	distal	3	no	24.405	23.308	EPSD	COSMIC	20.789	Down-regulation
AGC_DMPK_ROCK_ROCK2_ST	O95644	NFATC1	O75116	ROCK2	S772	D770N	770	Missense	proximal	-2	no	24.405	23.332	EPSD	COSMIC	20.789	Down-regulation
AGC_DMPK_ROCK_ROCK2_ST	O95644	NFATC1	O75116	ROCK2	S772	D770Y	770	Missense	proximal	-2	no	24.405	29.668	EPSD	COSMIC	20.789	Up-regulation
AGC_DMPK_ROCK_ROCK2_ST	Q96A00	PPP1R14A	O75116	ROCK2	S18	A20T	20	Missense	proximal	2	no	29.775	29.594	EPSD	COSMIC	20.789	Down-regulation
AGC_DMPK_ROCK_ROCK2_ST	Q96A00	PPP1R14A	O75116	ROCK2	S18	P23A	23	Missense	distal	5	no	29.775	29.211	EPSD	COSMIC	20.789	Down-regulation
AGC_DMPK_ROCK_ROCK2_ST	Q96A00	PPP1R14A	O75116	ROCK2	T38	V39I	39	Missense	proximal	1	no	34.400	34.359	PhosphoSitePlus	COSMIC;CCLE	20.789	Down-regulation
AGC_DMPK_ROCK_ROCK2_ST	Q96A00	PPP1R14A	O75116	ROCK2	T38	D42N	42	Missense	distal	4	no	34.400	32.935	PhosphoSitePlus	COSMIC	20.789	Down-regulation
AGC_DMPK_ROCK_ROCK2_ST	Q96A00	PPP1R14A	O75116	ROCK2	S128	P122L	122	Missense	distal	-6	no	30.294	29.605	EPSD	COSMIC	20.789	Down-regulation
AGC_DMPK_ROCK_ROCK2_ST	Q96A00	PPP1R14A	O75116	ROCK2	S130	S136N	136	Missense	distal	6	no	26.835	27.273	EPSD	COSMIC	20.789	Up-regulation
AGC_DMPK_ROCK_ROCK2_ST	Q96A00	PPP1R14A	O75116	ROCK2	S136	S136N	136	Missense	central	0	yes	32.346	0.000	EPSD	COSMIC	20.789	Loss
AGC_DMPK_ROCK_ROCK2_ST	Q96A00	PPP1R14A	O75116	ROCK2	S136	L138F	138	Missense	proximal	2	no	32.346	32.075	EPSD	COSMIC	20.789	Down-regulation
AGC_DMPK_ROCK_ROCK2_ST	Q96A00	PPP1R14A	O75116	ROCK2	S136	R141W	141	Missense	distal	5	no	32.346	32.122	EPSD	COSMIC;GDSC	20.789	Down-regulation
AGC_DMPK_ROCK_ROCK2_ST	O75116	ROCK2	O75116	ROCK2	T7	A13V	13	Missense	distal	6	no	31.941	32.321	EPSD	COSMIC	20.789	Up-regulation
AGC_DMPK_ROCK_ROCK2_ST	O75116	ROCK2	O75116	ROCK2	T7	K9N	9	Missense	proximal	2	no	31.941	31.620	EPSD	COSMIC	20.789	Down-regulation
AGC_DMPK_ROCK_ROCK2_ST	O75116	ROCK2	O75116	ROCK2	T7	P11L	11	Missense	distal	4	no	31.941	31.460	EPSD	COSMIC	20.789	Down-regulation
AGC_DMPK_ROCK_ROCK2_ST	O75116	ROCK2	O75116	ROCK2	T16	A13V	13	Missense	distal	-3	no	23.398	9.006	EPSD	COSMIC	20.789	Loss
AGC_DMPK_ROCK_ROCK2_ST	O75116	ROCK2	O75116	ROCK2	T16	K9N	9	Missense	distal	-7	no	23.398	23.482	EPSD	COSMIC	20.789	Up-regulation
AGC_DMPK_ROCK_ROCK2_ST	O75116	ROCK2	O75116	ROCK2	T16	P11L	11	Missense	distal	-5	no	23.398	21.222	EPSD	COSMIC	20.789	Down-regulation
AGC_DMPK_ROCK_ROCK2_ST	O75116	ROCK2	O75116	ROCK2	S1379	A1383T	1383	Missense	distal	4	no	39.468	39.767	EPSD;PhosphoSitePlus	COSMIC	20.789	Up-regulation
AGC_DMPK_ROCK_ROCK2_ST	O75116	ROCK2	O75116	ROCK2	S1379	R1380Q	1380	Missense	proximal	1	no	39.468	39.499	EPSD;PhosphoSitePlus	COSMIC	20.789	Up-regulation
AGC_DMPK_ROCK_ROCK2_ST	O75116	ROCK2	O75116	ROCK2	S1379	R1377Q	1377	Missense	proximal	-2	no	39.468	30.626	EPSD;PhosphoSitePlus	COSMIC;GDSC;CCLE	20.789	Down-regulation
AGC_DMPK_ROCK_ROCK2_ST	P98082	DAB2	O75116	ROCK2	S24	K26M	26	Missense	proximal	2	no	22.148	21.682	EPSD	COSMIC	20.789	Down-regulation
AGC_DMPK_ROCK_ROCK2_ST	P98082	DAB2	O75116	ROCK2	S24	P23L	23	Missense	proximal	-1	no	22.148	22.319	EPSD	COSMIC	20.789	Up-regulation
AGC_DMPK_ROCK_ROCK2_ST	P98082	DAB2	O75116	ROCK2	S24	G31V	31	Missense	distal	7	no	22.148	21.173	EPSD	COSMIC	20.789	Down-regulation
AGC_DMPK_ROCK_ROCK2_ST	P98082	DAB2	O75116	ROCK2	S24	A18S	18	Missense	distal	-6	no	22.148	22.657	EPSD	COSMIC	20.789	Up-regulation
AGC_DMPK_ROCK_ROCK2_ST	P98082	DAB2	O75116	ROCK2	T329	S326G	326	Missense	distal	-3	no	20.030	25.750	EPSD	COSMIC	20.789	Gain
AGC_DMPK_ROCK_ROCK2_ST	P98082	DAB2	O75116	ROCK2	S680	T674A	674	Missense	distal	-6	no	22.187	20.759	EPSD	COSMIC	20.789	Loss
AGC_DMPK_ROCK_ROCK2_ST	P98082	DAB2	O75116	ROCK2	S680	A681V	681	Missense	proximal	1	no	22.187	22.125	EPSD	COSMIC	20.789	Down-regulation
AGC_DMPK_ROCK_ROCK2_ST	P98082	DAB2	O75116	ROCK2	S723	V722I	722	Missense	proximal	-1	no	30.116	30.451	PhosphoSitePlus	COSMIC	20.789	Up-regulation
AGC_DMPK_ROCK_ROCK2_ST	P98082	DAB2	O75116	ROCK2	S723	Q721K	721	Missense	proximal	-2	no	30.116	30.005	PhosphoSitePlus	COSMIC	20.789	Down-regulation
AGC_DMPK_ROCK_ROCK2_ST	P98082	DAB2	O75116	ROCK2	S723	L724M	724	Missense	proximal	1	no	30.116	30.006	PhosphoSitePlus	COSMIC	20.789	Down-regulation
AGC_DMPK_ROCK_ROCK2_ST	P98082	DAB2	O75116	ROCK2	S723	K716N	716	Missense	distal	-7	no	30.116	30.201	PhosphoSitePlus	COSMIC	20.789	Up-regulation
AGC_DMPK_ROCK_ROCK2_ST	P98082	DAB2	O75116	ROCK2	S723	Q721H	721	Missense	proximal	-2	no	30.116	30.185	PhosphoSitePlus	COSMIC	20.789	Up-regulation
AGC_DMPK_ROCK_ROCK2_ST	P98082	DAB2	O75116	ROCK2	S723	P725S	725	Missense	proximal	2	no	30.116	30.238	PhosphoSitePlus	COSMIC	20.789	Up-regulation
AGC_DMPK_ROCK_ROCK2_ST	P98082	DAB2	O75116	ROCK2	S723	A718D	718	Missense	distal	-5	no	30.116	28.231	PhosphoSitePlus	COSMIC	20.789	Down-regulation
AGC_DMPK_ROCK_ROCK2_ST	P98082	DAB2	O75116	ROCK2	S723	A718S	718	Missense	distal	-5	no	30.116	29.872	PhosphoSitePlus	COSMIC	20.789	Down-regulation
AGC_DMPK_ROCK_ROCK2_ST	Q99962	SH3GL2	O75116	ROCK2	T14	V17G	17	Missense	distal	3	no	41.153	41.055	PhosphoSitePlus	COSMIC	20.789	Down-regulation
AGC_DMPK_ROCK_ROCK2_ST	Q99962	SH3GL2	O75116	ROCK2	S262	P257L	257	Missense	distal	-5	no	23.343	21.167	EPSD	COSMIC	20.789	Down-regulation
AGC_DMPK_ROCK_ROCK2_ST	Q99962	SH3GL2	O75116	ROCK2	S262	T267N	267	Missense	distal	5	no	23.343	22.748	EPSD	COSMIC	20.789	Down-regulation
AGC_DMPK_ROCK_ROCK2_ST	Q99962	SH3GL2	O75116	ROCK2	S262	G268E	268	Missense	distal	6	no	23.343	23.135	EPSD	COSMIC	20.789	Down-regulation
AGC_DMPK_ROCK_ROCK2_ST	P05067	APP	O75116	ROCK2	S271	T269A	269	Missense	proximal	-2	no	27.612	27.059	EPSD	COSMIC	20.789	Down-regulation
AGC_DMPK_ROCK_ROCK2_ST	P05067	APP	O75116	ROCK2	S271	T269I	269	Missense	proximal	-2	no	27.612	24.026	EPSD	COSMIC	20.789	Down-regulation
AGC_DMPK_ROCK_ROCK2_ST	P05067	APP	O75116	ROCK2	T276	T269A	269	Missense	distal	-7	no	22.158	21.860	EPSD	COSMIC	20.789	Down-regulation
AGC_DMPK_ROCK_ROCK2_ST	P05067	APP	O75116	ROCK2	T276	T269I	269	Missense	distal	-7	no	22.158	22.505	EPSD	COSMIC	20.789	Up-regulation
AGC_DMPK_ROCK_ROCK2_ST	P05067	APP	O75116	ROCK2	T276	E281K	281	Missense	distal	5	no	22.158	20.731	EPSD	COSMIC	20.789	Loss
AGC_DMPK_ROCK_ROCK2_ST	P05067	APP	O75116	ROCK2	S348	Q354K	354	Missense	distal	6	no	21.197	20.628	EPSD	COSMIC	20.789	Loss
AGC_DMPK_ROCK_ROCK2_ST	P05067	APP	O75116	ROCK2	S348	L350R	350	Missense	proximal	2	no	21.197	20.887	EPSD	COSMIC	20.789	Down-regulation
AGC_DMPK_ROCK_ROCK2_ST	P05067	APP	O75116	ROCK2	S587	P584Q	584	Missense	distal	-3	no	20.128	21.659	EPSD	COSMIC	20.789	Gain
AGC_DMPK_ROCK_ROCK2_ST	P05067	APP	O75116	ROCK2	S679	G680R	680	Missense	proximal	1	no	23.926	23.848	EPSD	COSMIC	20.789	Down-regulation
AGC_DMPK_ROCK_ROCK2_ST	P05067	APP	O75116	ROCK2	S679	H684Q	684	Missense	distal	5	no	23.926	24.528	EPSD	COSMIC	20.789	Up-regulation
AGC_DMPK_ROCK_ROCK2_ST	P05067	APP	O75116	ROCK2	S679	Q686H	686	Missense	distal	7	no	23.926	23.421	EPSD	COSMIC	20.789	Down-regulation
AGC_DMPK_ROCK_ROCK2_ST	P05067	APP	O75116	ROCK2	S679	Q686P	686	Missense	distal	7	no	23.926	23.845	EPSD	COSMIC	20.789	Down-regulation
AGC_DMPK_ROCK_ROCK2_ST	P05067	APP	O75116	ROCK2	S679	S679L	679	Missense	central	0	yes	23.926	0.000	EPSD	COSMIC	20.789	Loss
AGC_DMPK_ROCK_ROCK2_ST	P05067	APP	O75116	ROCK2	S679	Q686K	686	Missense	distal	7	no	23.926	23.134	EPSD	COSMIC	20.789	Down-regulation
AGC_DMPK_ROCK_ROCK2_ST	P05067	APP	O75116	ROCK2	S679	V683I	683	Missense	distal	4	no	23.926	24.510	EPSD	COSMIC	20.789	Up-regulation
AGC_DMPK_ROCK_ROCK2_ST	P05067	APP	O75116	ROCK2	S679	A673S	673	Missense	distal	-6	no	23.926	24.435	EPSD	COSMIC	20.789	Up-regulation
AGC_DMPK_ROCK_ROCK2_ST	P05067	APP	O75116	ROCK2	T729	S730Y	730	Missense	proximal	1	no	32.174	32.115	EPSD	COSMIC	20.789	Down-regulation
AGC_DMPK_ROCK_ROCK2_ST	P05067	APP	O75116	ROCK2	S730	S730Y	730	Missense	central	0	yes	28.131	0.000	EPSD	COSMIC	20.789	Loss
AGC_DMPK_ROCK_ROCK2_ST	P05067	APP	O75116	ROCK2	T761	E758K	758	Missense	distal	-3	no	17.874	26.253	EPSD	COSMIC	20.789	Gain
AGC_DMPK_ROCK_ROCK2_ST	P53671	LIMK2	O75116	ROCK2	S283	R286C	286	Missense	distal	3	no	24.646	25.377	EPSD	COSMIC	20.789	Up-regulation
AGC_DMPK_ROCK_ROCK2_ST	P53671	LIMK2	O75116	ROCK2	S283	R282C	282	Missense	proximal	-1	no	24.646	23.374	EPSD	COSMIC	20.789	Down-regulation
AGC_DMPK_ROCK_ROCK2_ST	P53671	LIMK2	O75116	ROCK2	S283	R286H	286	Missense	distal	3	no	24.646	26.430	EPSD	COSMIC;CCLE	20.789	Up-regulation
AGC_DMPK_ROCK_ROCK2_ST	P53671	LIMK2	O75116	ROCK2	S283	T278R	278	Missense	distal	-5	no	24.646	25.673	EPSD	COSMIC	20.789	Up-regulation
AGC_DMPK_ROCK_ROCK2_ST	P53671	LIMK2	O75116	ROCK2	S283	R280M	280	Missense	distal	-3	no	24.646	18.222	EPSD	COSMIC	20.789	Loss
AGC_DMPK_ROCK_ROCK2_ST	P53671	LIMK2	O75116	ROCK2	S283	S283F	283	Missense	central	0	yes	24.646	0.000	EPSD	COSMIC	20.789	Loss
AGC_DMPK_ROCK_ROCK2_ST	P53671	LIMK2	O75116	ROCK2	S283	S289R	289	Missense	distal	6	no	24.646	24.610	EPSD	COSMIC	20.789	Down-regulation
AGC_DMPK_ROCK_ROCK2_ST	P53671	LIMK2	O75116	ROCK2	S283	R286Q	286	Missense	distal	3	no	24.646	25.510	EPSD	COSMIC	20.789	Up-regulation
AGC_DMPK_ROCK_ROCK2_ST	P53671	LIMK2	O75116	ROCK2	T505	P510H	510	Missense	distal	5	no	34.788	34.240	PhosphoSitePlus	COSMIC	20.789	Down-regulation
AGC_DMPK_ROCK_ROCK2_ST	P53671	LIMK2	O75116	ROCK2	T505	R503C	503	Missense	proximal	-2	no	34.788	11.384	PhosphoSitePlus	COSMIC	20.789	Loss
AGC_DMPK_ROCK_ROCK2_ST	Q15417	CNN3	O75116	ROCK2	S9	G7S	7	Missense	proximal	-2	no	32.433	29.113	EPSD	COSMIC	20.789	Down-regulation
AGC_DMPK_ROCK_ROCK2_ST	Q15417	CNN3	O75116	ROCK2	S13	G7S	7	Missense	distal	-6	no	22.017	19.778	EPSD	COSMIC	20.789	Loss
AGC_DMPK_ROCK_ROCK2_ST	Q15417	CNN3	O75116	ROCK2	T170	M168T	168	Missense	proximal	-2	no	27.004	17.329	EPSD	COSMIC;GDSC	20.789	Loss
AGC_DMPK_ROCK_ROCK2_ST	Q15417	CNN3	O75116	ROCK2	T170	V163I	163	Missense	distal	-7	no	27.004	27.329	EPSD	COSMIC	20.789	Up-regulation
AGC_DMPK_ROCK_ROCK2_ST	Q15417	CNN3	O75116	ROCK2	T170	C173Y	173	Missense	distal	3	no	27.004	27.383	EPSD	COSMIC	20.789	Up-regulation
AGC_DMPK_ROCK_ROCK2_ST	Q15417	CNN3	O75116	ROCK2	T170	G165C	165	Missense	distal	-5	no	27.004	22.697	EPSD	COSMIC	20.789	Down-regulation
AGC_DMPK_ROCK_ROCK2_ST	Q15417	CNN3	O75116	ROCK2	S175	C173Y	173	Missense	proximal	-2	no	13.886	29.483	EPSD	COSMIC	20.789	Gain
AGC_DMPK_ROCK_ROCK2_ST	Q15417	CNN3	O75116	ROCK2	T180	R185K	185	Missense	distal	5	no	25.595	24.548	EPSD	COSMIC	20.789	Down-regulation
AGC_DMPK_ROCK_ROCK2_ST	Q15417	CNN3	O75116	ROCK2	T180	A181V	181	Missense	proximal	1	no	25.595	25.534	EPSD	COSMIC	20.789	Down-regulation
AGC_DMPK_ROCK_ROCK2_ST	Q15417	CNN3	O75116	ROCK2	T180	C173Y	173	Missense	distal	-7	no	25.595	26.057	EPSD	COSMIC	20.789	Up-regulation
AGC_DMPK_ROCK_ROCK2_ST	Q15417	CNN3	O75116	ROCK2	T180	M179I	179	Missense	proximal	-1	no	25.595	25.903	EPSD	COSMIC	20.789	Up-regulation
AGC_DMPK_ROCK_ROCK2_ST	Q15417	CNN3	O75116	ROCK2	T184	R185K	185	Missense	proximal	1	no	29.220	29.357	EPSD	COSMIC	20.789	Up-regulation
AGC_DMPK_ROCK_ROCK2_ST	Q15417	CNN3	O75116	ROCK2	T184	A181V	181	Missense	distal	-3	no	29.220	14.829	EPSD	COSMIC	20.789	Loss
AGC_DMPK_ROCK_ROCK2_ST	Q15417	CNN3	O75116	ROCK2	T184	M179I	179	Missense	distal	-5	no	29.220	25.811	EPSD	COSMIC	20.789	Down-regulation
AGC_DMPK_ROCK_ROCK2_ST	Q15417	CNN3	O75116	ROCK2	T210	S215I	215	Missense	distal	5	no	25.163	25.455	EPSD	COSMIC	20.789	Up-regulation
AGC_DMPK_ROCK_ROCK2_ST	Q15417	CNN3	O75116	ROCK2	T210	T203K	203	Missense	distal	-7	no	25.163	25.151	EPSD	COSMIC	20.789	Down-regulation
AGC_DMPK_ROCK_ROCK2_ST	Q15417	CNN3	O75116	ROCK2	S215	S215I	215	Missense	central	0	yes	29.866	0.000	EPSD	COSMIC	20.789	Loss
AGC_DMPK_ROCK_ROCK2_ST	Q15417	CNN3	O75116	ROCK2	T234	P237L	237	Missense	distal	3	no	22.720	24.184	EPSD	COSMIC;GDSC;CCLE	20.789	Up-regulation
AGC_DMPK_ROCK_ROCK2_ST	Q15417	CNN3	O75116	ROCK2	T249	T242K	242	Missense	distal	-7	no	26.503	26.492	EPSD	COSMIC	20.789	Down-regulation
AGC_DMPK_ROCK_ROCK2_ST	Q15417	CNN3	O75116	ROCK2	S293	S298N	298	Missense	distal	5	no	38.489	37.888	PhosphoSitePlus	COSMIC	20.789	Down-regulation
AGC_DMPK_ROCK_ROCK2_ST	Q15417	CNN3	O75116	ROCK2	S296	S298N	298	Missense	proximal	2	no	24.676	24.723	EPSD	COSMIC	20.789	Up-regulation
AGC_DMPK_ROCK_ROCK2_ST	Q15417	CNN3	O75116	ROCK2	S323	Y316H	316	Missense	distal	-7	no	23.116	22.166	EPSD	COSMIC;GDSC;CCLE	20.789	Down-regulation
AGC_DMPK_ROCK_ROCK2_ST	Q96C90	PPP1R14B	O75116	ROCK2	S21	A14T	14	Missense	distal	-7	no	23.972	24.269	EPSD	COSMIC	20.789	Up-regulation
AGC_DMPK_ROCK_ROCK2_ST	Q96C90	PPP1R14B	O75116	ROCK2	S21	G18R	18	Missense	distal	-3	no	23.972	32.156	EPSD	COSMIC	20.789	Up-regulation
AGC_DMPK_ROCK_ROCK2_ST	Q96C90	PPP1R14B	O75116	ROCK2	S142	T143I	143	Missense	proximal	1	no	30.324	30.279	EPSD	COSMIC	20.789	Down-regulation
AGC_DMPK_ROCK_ROCK2_ST	Q96C90	PPP1R14B	O75116	ROCK2	S142	R136W	136	Missense	distal	-6	no	30.324	28.168	EPSD	COSMIC	20.789	Down-regulation
AGC_DMPK_ROCK_ROCK2_ST	Q96C90	PPP1R14B	O75116	ROCK2	T143	T143I	143	Missense	central	0	yes	24.071	0.000	EPSD	COSMIC	20.789	Loss
AGC_DMPK_ROCK_ROCK2_ST	Q96C90	PPP1R14B	O75116	ROCK2	T143	R136W	136	Missense	distal	-7	no	24.071	24.353	EPSD	COSMIC	20.789	Up-regulation
AGC_DMPK_ROCK_ROCK2_ST	P68104	EEF1A1	O75116	ROCK2	S21	G25C	25	Missense	distal	4	no	24.313	25.028	EPSD	COSMIC	20.789	Up-regulation
AGC_DMPK_ROCK_ROCK2_ST	P68104	EEF1A1	O75116	ROCK2	S21	H26R	26	Missense	distal	5	no	24.313	24.748	EPSD	COSMIC	20.789	Up-regulation
AGC_DMPK_ROCK_ROCK2_ST	P68104	EEF1A1	O75116	ROCK2	T22	G25C	25	Missense	distal	3	no	20.963	20.460	EPSD	COSMIC	20.789	Loss
AGC_DMPK_ROCK_ROCK2_ST	P68104	EEF1A1	O75116	ROCK2	T22	H26R	26	Missense	distal	4	no	20.963	21.351	EPSD	COSMIC	20.789	Up-regulation
AGC_DMPK_ROCK_ROCK2_ST	P68104	EEF1A1	O75116	ROCK2	T24	G25C	25	Missense	proximal	1	no	22.142	22.138	EPSD	COSMIC	20.789	Down-regulation
AGC_DMPK_ROCK_ROCK2_ST	P68104	EEF1A1	O75116	ROCK2	T24	H26R	26	Missense	proximal	2	no	22.142	21.874	EPSD	COSMIC	20.789	Down-regulation
AGC_DMPK_ROCK_ROCK2_ST	P68104	EEF1A1	O75116	ROCK2	S163	Q164R	164	Missense	proximal	1	no	26.427	26.396	EPSD	COSMIC	20.789	Down-regulation
AGC_DMPK_ROCK_ROCK2_ST	P68104	EEF1A1	O75116	ROCK2	S383	R381C	381	Missense	proximal	-2	no	27.210	3.806	EPSD	COSMIC	20.789	Loss
AGC_DMPK_ROCK_ROCK2_ST	P68104	EEF1A1	O75116	ROCK2	S383	K376T	376	Missense	distal	-7	no	27.210	27.222	EPSD	COSMIC	20.789	Up-regulation
AGC_DMPK_ROCK_ROCK2_ST	P68104	EEF1A1	O75116	ROCK2	T432	R430K	430	Missense	proximal	-2	no	35.861	26.908	PhosphoSitePlus	COSMIC	20.789	Down-regulation
AGC_DMPK_ROCK_ROCK2_ST	P68104	EEF1A1	O75116	ROCK2	T432	V433L	433	Missense	proximal	1	no	35.861	35.901	PhosphoSitePlus	COSMIC	20.789	Up-regulation
AGC_DMPK_ROCK_ROCK2_ST	O14974	PPP1R12A	O75116	ROCK2	S477	S478C	478	Missense	proximal	1	no	22.795	22.756	EPSD	COSMIC	20.789	Down-regulation
AGC_DMPK_ROCK_ROCK2_ST	O14974	PPP1R12A	O75116	ROCK2	S478	S478C	478	Missense	central	0	yes	24.684	0.000	EPSD	COSMIC	20.789	Loss
AGC_DMPK_ROCK_ROCK2_ST	O14974	PPP1R12A	O75116	ROCK2	S668	R663I	663	Missense	distal	-5	no	21.836	17.461	EPSD	COSMIC	20.789	Loss
AGC_DMPK_ROCK_ROCK2_ST	O14974	PPP1R12A	O75116	ROCK2	T696	R694I	694	Missense	proximal	-2	no	40.321	24.305	PhosphoSitePlus	COSMIC	20.789	Down-regulation
AGC_DMPK_ROCK_ROCK2_ST	O14974	PPP1R12A	O75116	ROCK2	S852	R851H	851	Missense	proximal	-1	no	31.029	30.841	EPSD	COSMIC	20.789	Down-regulation
AGC_DMPK_ROCK_ROCK2_ST	O14974	PPP1R12A	O75116	ROCK2	S852	R851C	851	Missense	proximal	-1	no	31.029	29.756	EPSD	COSMIC	20.789	Down-regulation
AGC_DMPK_ROCK_ROCK2_ST	O14974	PPP1R12A	O75116	ROCK2	T853	R851H	851	Missense	proximal	-2	no	31.689	22.916	EPSD	COSMIC	20.789	Down-regulation
AGC_DMPK_ROCK_ROCK2_ST	O14974	PPP1R12A	O75116	ROCK2	T853	R851C	851	Missense	proximal	-2	no	31.689	8.285	EPSD	COSMIC	20.789	Loss
AGC_DMPK_ROCK_ROCK2_ST	O14974	PPP1R12A	O75116	ROCK2	S856	R851H	851	Missense	distal	-5	no	21.083	20.005	EPSD	COSMIC	20.789	Loss
AGC_DMPK_ROCK_ROCK2_ST	O14974	PPP1R12A	O75116	ROCK2	S856	R851C	851	Missense	distal	-5	no	21.083	14.998	EPSD	COSMIC	20.789	Loss
AGC_DMPK_ROCK_ROCK2_ST	O14974	PPP1R12A	O75116	ROCK2	T892	G898D	898	Missense	distal	6	no	31.348	32.089	EPSD	COSMIC	20.789	Up-regulation
AGC_DMPK_ROCK_ROCK2_ST	O14974	PPP1R12A	O75116	ROCK2	T892	R889G	889	Missense	distal	-3	no	31.348	23.164	EPSD	COSMIC	20.789	Down-regulation
AGC_DMPK_ROCK_ROCK2_ST	O14974	PPP1R12A	O75116	ROCK2	T892	S888F	888	Missense	distal	-4	no	31.348	32.784	EPSD	COSMIC	20.789	Up-regulation
STE_STE-Unique_MAP3K14_ST	P61160	ACTR2	Q99558	MAP3K14	T110	I107M	107	Missense	distal	-3	no	220.276	220.447	EPSD	COSMIC	201.043	Up-regulation
STE_STE-Unique_MAP3K14_ST	P25963	NFKBIA	Q99558	MAP3K14	S32	M37K	37	Missense	distal	5	no	360.434	360.902	EPSD;PhosphoSitePlus	COSMIC	201.043	Up-regulation
STE_STE-Unique_MAP3K14_ST	P25963	NFKBIA	Q99558	MAP3K14	S32	S36P	36	Missense	distal	4	no	360.434	333.795	EPSD;PhosphoSitePlus	COSMIC	201.043	Down-regulation
STE_STE-Unique_MAP3K14_ST	P25963	NFKBIA	Q99558	MAP3K14	S32	S32N	32	Missense	central	0	yes	360.434	0.000	EPSD;PhosphoSitePlus	COSMIC	201.043	Loss
STE_STE-Unique_MAP3K14_ST	P25963	NFKBIA	Q99558	MAP3K14	S36	M37K	37	Missense	proximal	1	no	397.236	400.386	PhosphoSitePlus;EPSD	COSMIC	201.043	Up-regulation
STE_STE-Unique_MAP3K14_ST	P25963	NFKBIA	Q99558	MAP3K14	S36	E40D	40	Missense	distal	4	no	397.236	392.994	PhosphoSitePlus;EPSD	COSMIC	201.043	Down-regulation
STE_STE-Unique_MAP3K14_ST	P25963	NFKBIA	Q99558	MAP3K14	S36	E43K	43	Missense	distal	7	no	397.236	389.960	PhosphoSitePlus;EPSD	COSMIC	201.043	Down-regulation
STE_STE-Unique_MAP3K14_ST	P25963	NFKBIA	Q99558	MAP3K14	S36	S36P	36	Missense	central	0	yes	397.236	0.000	PhosphoSitePlus;EPSD	COSMIC	201.043	Loss
STE_STE-Unique_MAP3K14_ST	P25963	NFKBIA	Q99558	MAP3K14	S36	E43Q	43	Missense	distal	7	no	397.236	396.168	PhosphoSitePlus;EPSD	COSMIC	201.043	Down-regulation
STE_STE-Unique_MAP3K14_ST	P25963	NFKBIA	Q99558	MAP3K14	S36	S32N	32	Missense	distal	-4	no	397.236	382.571	PhosphoSitePlus;EPSD	COSMIC	201.043	Down-regulation
STE_STE-Unique_MAP3K14_ST	P25963	NFKBIA	Q99558	MAP3K14	T291	T291K	291	Missense	central	0	yes	221.515	0.000	EPSD	COSMIC	201.043	Loss
STE_STE-Unique_MAP3K14_ST	P25963	NFKBIA	Q99558	MAP3K14	T291	E284D	284	Missense	distal	-7	no	221.515	222.469	EPSD	COSMIC	201.043	Up-regulation
STE_STE-Unique_MAP3K14_ST	P25963	NFKBIA	Q99558	MAP3K14	T291	T291P	291	Missense	central	0	yes	221.515	0.000	EPSD	COSMIC	201.043	Loss
STE_STE-Unique_MAP3K14_ST	P25963	NFKBIA	Q99558	MAP3K14	T291	E287V	287	Missense	distal	-4	no	221.515	226.898	EPSD	COSMIC	201.043	Up-regulation
STE_STE-Unique_MAP3K14_ST	P25963	NFKBIA	Q99558	MAP3K14	T291	Y289C	289	Missense	proximal	-2	no	221.515	217.472	EPSD	COSMIC	201.043	Down-regulation
STE_STE-Unique_MAP3K14_ST	P25963	NFKBIA	Q99558	MAP3K14	S293	T291K	291	Missense	proximal	-2	no	244.510	253.994	EPSD	COSMIC	201.043	Up-regulation
STE_STE-Unique_MAP3K14_ST	P25963	NFKBIA	Q99558	MAP3K14	S293	T291P	291	Missense	proximal	-2	no	244.510	236.954	EPSD	COSMIC	201.043	Down-regulation
STE_STE-Unique_MAP3K14_ST	P25963	NFKBIA	Q99558	MAP3K14	S293	E287V	287	Missense	distal	-6	no	244.510	206.481	EPSD	COSMIC	201.043	Down-regulation
STE_STE-Unique_MAP3K14_ST	P25963	NFKBIA	Q99558	MAP3K14	S293	Y289C	289	Missense	distal	-4	no	244.510	244.398	EPSD	COSMIC	201.043	Down-regulation
STE_STE-Unique_MAP3K14_ST	O15111	CHUK	Q99558	MAP3K14	S176	S180F	180	Missense	distal	4	no	389.213	359.296	PhosphoSitePlus;EPSD	COSMIC	201.043	Down-regulation
STE_STE-Unique_MAP3K14_ST	O15111	CHUK	Q99558	MAP3K14	S180	S180F	180	Missense	central	0	yes	352.976	0.000	EPSD;PhosphoSitePlus	COSMIC	201.043	Loss
STE_STE-Unique_MAP3K14_ST	O15111	CHUK	Q99558	MAP3K14	S473	K479E	479	Missense	distal	6	no	196.135	206.319	EPSD	COSMIC	201.043	Gain
STE_STE-Unique_MAP3K14_ST	O15111	CHUK	Q99558	MAP3K14	S581	S579F	579	Missense	proximal	-2	no	225.742	223.897	EPSD	COSMIC	201.043	Down-regulation
STE_STE-Unique_MAP3K14_ST	O14920	IKBKB	Q99558	MAP3K14	S177	E172G	172	Missense	distal	-5	no	371.956	354.018	PhosphoSitePlus;EPSD	COSMIC	201.043	Down-regulation
STE_STE-Unique_MAP3K14_ST	O14920	IKBKB	Q99558	MAP3K14	S177	K171E	171	Missense	distal	-6	no	371.956	378.579	PhosphoSitePlus;EPSD	COSMIC;CCLE	201.043	Up-regulation
STE_STE-Unique_MAP3K14_ST	O14920	IKBKB	Q99558	MAP3K14	S177	A170T	170	Missense	distal	-7	no	371.956	379.621	PhosphoSitePlus;EPSD	COSMIC	201.043	Up-regulation
STE_STE-Unique_MAP3K14_ST	O14920	IKBKB	Q99558	MAP3K14	S177	K171T	171	Missense	distal	-6	no	371.956	355.114	PhosphoSitePlus;EPSD	COSMIC	201.043	Down-regulation
STE_STE-Unique_MAP3K14_ST	O14920	IKBKB	Q99558	MAP3K14	S177	K171M	171	Missense	distal	-6	no	371.956	349.601	PhosphoSitePlus;EPSD	COSMIC	201.043	Down-regulation
STE_STE-Unique_MAP3K14_ST	O14920	IKBKB	Q99558	MAP3K14	S177	K171Q	171	Missense	distal	-6	no	371.956	374.655	PhosphoSitePlus;EPSD	COSMIC	201.043	Up-regulation
STE_STE-Unique_MAP3K14_ST	O14920	IKBKB	Q99558	MAP3K14	S239	R236W	236	Missense	distal	-3	no	204.532	204.658	EPSD	COSMIC	201.043	Up-regulation
STE_STE-Unique_MAP3K14_ST	O14920	IKBKB	Q99558	MAP3K14	S239	V241E	241	Missense	proximal	2	no	204.532	204.771	EPSD	COSMIC	201.043	Up-regulation
STE_STE-Unique_MAP3K14_ST	O14920	IKBKB	Q99558	MAP3K14	S256	G251E	251	Missense	distal	-5	no	226.542	244.480	EPSD	COSMIC	201.043	Up-regulation
STE_STE-Unique_MAP3K14_ST	O14920	IKBKB	Q99558	MAP3K14	S256	F255V	255	Missense	proximal	-1	no	226.542	230.444	EPSD	COSMIC	201.043	Up-regulation
STE_STE-Unique_MAP3K14_ST	O14920	IKBKB	Q99558	MAP3K14	S256	L249F	249	Missense	distal	-7	no	226.542	223.464	EPSD	COSMIC	201.043	Down-regulation
STE_STE-Unique_MAP3K14_ST	O14920	IKBKB	Q99558	MAP3K14	S256	S258Y	258	Missense	proximal	2	no	226.542	227.797	EPSD	COSMIC	201.043	Up-regulation
STE_STE-Unique_MAP3K14_ST	O14920	IKBKB	Q99558	MAP3K14	S256	S256Y	256	Missense	central	0	yes	226.542	0.000	EPSD	COSMIC	201.043	Loss
STE_STE-Unique_MAP3K14_ST	O14920	IKBKB	Q99558	MAP3K14	T368	G374R	374	Missense	distal	6	no	205.138	190.447	EPSD	COSMIC	201.043	Loss
STE_STE-Unique_MAP3K14_ST	O14920	IKBKB	Q99558	MAP3K14	T368	P363H	363	Missense	distal	-5	no	205.138	206.546	EPSD	COSMIC	201.043	Up-regulation
STE_STE-Unique_MAP3K14_ST	O14920	IKBKB	Q99558	MAP3K14	T368	G374S	374	Missense	distal	6	no	205.138	206.119	EPSD	COSMIC;GDSC;CCLE	201.043	Up-regulation
STE_STE-Unique_MAP3K14_ST	O14920	IKBKB	Q99558	MAP3K14	T368	K375T	375	Missense	distal	7	no	205.138	206.412	EPSD	COSMIC	201.043	Up-regulation
STE_STE-Unique_MAP3K14_ST	O14920	IKBKB	Q99558	MAP3K14	S476	N470K	470	Missense	distal	-6	no	216.553	236.198	EPSD	COSMIC	201.043	Up-regulation
STE_STE-Unique_MAP3K14_ST	O14920	IKBKB	Q99558	MAP3K14	S476	K480T	480	Missense	distal	4	no	216.553	215.256	EPSD	COSMIC	201.043	Down-regulation
STE_STE-Unique_MAP3K14_ST	O14920	IKBKB	Q99558	MAP3K14	S489	D493N	493	Missense	distal	4	no	229.597	218.623	EPSD	COSMIC	201.043	Down-regulation
STE_STE-Unique_MAP3K14_ST	O14920	IKBKB	Q99558	MAP3K14	S489	Q491H	491	Missense	proximal	2	no	229.597	231.341	EPSD	COSMIC	201.043	Up-regulation
STE_STE-Unique_MAP3K14_ST	O14920	IKBKB	Q99558	MAP3K14	S489	D484Y	484	Missense	distal	-5	no	229.597	209.080	EPSD	COSMIC	201.043	Down-regulation
STE_STE-Unique_MAP3K14_ST	O14920	IKBKB	Q99558	MAP3K14	T501	T501P	501	Missense	central	0	yes	236.677	0.000	EPSD	COSMIC	201.043	Loss
STE_STE-Unique_MAP3K14_ST	O14920	IKBKB	Q99558	MAP3K14	T501	F503C	503	Missense	proximal	2	no	236.677	236.762	EPSD	COSMIC	201.043	Up-regulation
STE_STE-Unique_MAP3K14_ST	O14920	IKBKB	Q99558	MAP3K14	T501	E499K	499	Missense	proximal	-2	no	236.677	240.134	EPSD	COSMIC	201.043	Up-regulation
STE_STE-Unique_MAP3K14_ST	O14920	IKBKB	Q99558	MAP3K14	S550	D543N	543	Missense	distal	-7	no	251.826	244.965	EPSD	COSMIC	201.043	Down-regulation
STE_STE-Unique_MAP3K14_ST	O14920	IKBKB	Q99558	MAP3K14	T583	E589D	589	Missense	distal	6	no	216.886	210.715	EPSD	COSMIC	201.043	Down-regulation
STE_STE-Unique_MAP3K14_ST	O14920	IKBKB	Q99558	MAP3K14	T583	D580N	580	Missense	distal	-3	no	216.886	217.076	EPSD	COSMIC	201.043	Up-regulation
STE_STE-Unique_MAP3K14_ST	O14920	IKBKB	Q99558	MAP3K14	T583	E576K	576	Missense	distal	-7	no	216.886	223.153	EPSD	COSMIC	201.043	Up-regulation
STE_STE-Unique_MAP3K14_ST	O14920	IKBKB	Q99558	MAP3K14	T583	R579Q	579	Missense	distal	-4	no	216.886	219.095	EPSD	COSMIC;CCLE	201.043	Up-regulation
STE_STE-Unique_MAP3K14_ST	O14920	IKBKB	Q99558	MAP3K14	S587	E589D	589	Missense	proximal	2	no	249.693	246.378	EPSD	COSMIC	201.043	Down-regulation
STE_STE-Unique_MAP3K14_ST	O14920	IKBKB	Q99558	MAP3K14	S587	D580N	580	Missense	distal	-7	no	249.693	242.832	EPSD	COSMIC	201.043	Down-regulation
STE_STE-Unique_MAP3K14_ST	O14920	IKBKB	Q99558	MAP3K14	S587	R592W	592	Missense	distal	5	no	249.693	249.464	EPSD	COSMIC	201.043	Down-regulation
STE_STE-Unique_MAP3K14_ST	O14920	IKBKB	Q99558	MAP3K14	S692	T693M	693	Missense	proximal	1	no	222.696	215.042	EPSD	COSMIC;CCLE	201.043	Down-regulation
STE_STE-Unique_MAP3K14_ST	O14920	IKBKB	Q99558	MAP3K14	S692	A694V	694	Missense	proximal	2	no	222.696	221.406	EPSD	COSMIC	201.043	Down-regulation
STE_STE-Unique_MAP3K14_ST	O14920	IKBKB	Q99558	MAP3K14	S692	T693A	693	Missense	proximal	1	no	222.696	212.773	EPSD	COSMIC	201.043	Down-regulation
STE_STE-Unique_MAP3K14_ST	O14920	IKBKB	Q99558	MAP3K14	S692	S689F	689	Missense	distal	-3	no	222.696	222.635	EPSD	COSMIC	201.043	Down-regulation
STE_STE-Unique_MAP3K14_ST	O14920	IKBKB	Q99558	MAP3K14	S705	E706D	706	Missense	proximal	1	no	192.225	201.079	EPSD	COSMIC	201.043	Gain
STE_STE-Unique_MAP3K14_ST	O14920	IKBKB	Q99558	MAP3K14	S733	D738Y	738	Missense	distal	5	no	228.964	228.625	EPSD	COSMIC	201.043	Down-regulation
STE_STE-Unique_MAP3K14_ST	Q00653	NFKB2	Q99558	MAP3K14	S108	P102R	102	Missense	distal	-6	no	181.217	206.357	EPSD	COSMIC	201.043	Gain
STE_STE-Unique_MAP3K14_ST	Q00653	NFKB2	Q99558	MAP3K14	T811	P813L	813	Missense	proximal	2	no	226.871	225.011	EPSD	COSMIC	201.043	Down-regulation
STE_STE-Unique_MAP3K14_ST	Q00653	NFKB2	Q99558	MAP3K14	T859	P857H	857	Missense	proximal	-2	no	203.269	209.513	EPSD	COSMIC	201.043	Up-regulation
STE_STE-Unique_MAP3K14_ST	Q00653	NFKB2	Q99558	MAP3K14	S866	S872T	872	Missense	distal	6	no	356.089	343.187	EPSD;PhosphoSitePlus	COSMIC	201.043	Down-regulation
STE_STE-Unique_MAP3K14_ST	Q00653	NFKB2	Q99558	MAP3K14	S870	S872T	872	Missense	proximal	2	no	372.680	371.688	PhosphoSitePlus;EPSD	COSMIC	201.043	Down-regulation
AGC_RSK_RSKp70_RPS6KB1_ST	Q9BYV9	BACH2	P23443	RPS6KB1	T406	V402L	402	Missense	distal	-4	no	23.964	25.322	EPSD	COSMIC;GDSC;CCLE	24.279	Gain
AGC_RSK_RSKp70_RPS6KB1_ST	Q9BYV9	BACH2	P23443	RPS6KB1	S409	V402L	402	Missense	distal	-7	no	24.580	24.390	EPSD	COSMIC;GDSC;CCLE	24.279	Down-regulation
AGC_RSK_RSKp70_RPS6KB1_ST	Q9BYV9	BACH2	P23443	RPS6KB1	S409	S409L	409	Missense	central	0	yes	24.580	0.000	EPSD	COSMIC	24.279	Loss
AGC_RSK_RSKp70_RPS6KB1_ST	Q9BYV9	BACH2	P23443	RPS6KB1	S409	S403P	403	Missense	distal	-6	no	24.580	24.631	EPSD	COSMIC	24.279	Up-regulation
AGC_RSK_RSKp70_RPS6KB1_ST	Q9BYV9	BACH2	P23443	RPS6KB1	S521	S525F	525	Missense	distal	4	no	40.367	38.205	PhosphoSitePlus	COSMIC	24.279	Down-regulation
AGC_RSK_RSKp70_RPS6KB1_ST	Q9BYV9	BACH2	P23443	RPS6KB1	S521	T519I	519	Missense	proximal	-2	no	40.367	40.379	PhosphoSitePlus	COSMIC	24.279	Up-regulation
AGC_RSK_RSKp70_RPS6KB1_ST	Q9BYV9	BACH2	P23443	RPS6KB1	S521	E514K	514	Missense	distal	-7	no	40.367	40.468	PhosphoSitePlus	COSMIC	24.279	Up-regulation
AGC_RSK_RSKp70_RPS6KB1_ST	Q9BYV9	BACH2	P23443	RPS6KB1	S521	T515N	515	Missense	distal	-6	no	40.367	40.375	PhosphoSitePlus	COSMIC	24.279	Up-regulation
AGC_RSK_RSKp70_RPS6KB1_ST	Q9BYV9	BACH2	P23443	RPS6KB1	S521	C523Y	523	Missense	proximal	2	no	40.367	38.883	PhosphoSitePlus	COSMIC	24.279	Down-regulation
AGC_RSK_RSKp70_RPS6KB1_ST	Q9BYV9	BACH2	P23443	RPS6KB1	S521	E514D	514	Missense	distal	-7	no	40.367	40.631	PhosphoSitePlus	COSMIC;GDSC;CCLE	24.279	Up-regulation
AGC_RSK_RSKp70_RPS6KB1_ST	Q9BYV9	BACH2	P23443	RPS6KB1	S525	S525F	525	Missense	central	0	yes	30.986	0.000	EPSD	COSMIC	24.279	Loss
AGC_RSK_RSKp70_RPS6KB1_ST	Q9BYV9	BACH2	P23443	RPS6KB1	S525	T519I	519	Missense	distal	-6	no	30.986	31.028	EPSD	COSMIC	24.279	Up-regulation
AGC_RSK_RSKp70_RPS6KB1_ST	Q9BYV9	BACH2	P23443	RPS6KB1	S525	C523Y	523	Missense	proximal	-2	no	30.986	29.689	EPSD	COSMIC	24.279	Down-regulation
AGC_RSK_RSKp70_RPS6KB1_ST	Q9BYV9	BACH2	P23443	RPS6KB1	S527	G534V	534	Missense	distal	7	no	26.399	25.859	EPSD	COSMIC;GDSC;CCLE	24.279	Down-regulation
AGC_RSK_RSKp70_RPS6KB1_ST	Q9BYV9	BACH2	P23443	RPS6KB1	S527	S525F	525	Missense	proximal	-2	no	26.399	28.265	EPSD	COSMIC	24.279	Up-regulation
AGC_RSK_RSKp70_RPS6KB1_ST	Q9BYV9	BACH2	P23443	RPS6KB1	S527	C523Y	523	Missense	distal	-4	no	26.399	27.826	EPSD	COSMIC	24.279	Up-regulation
AGC_RSK_RSKp70_RPS6KB1_ST	P35568	IRS1	P23443	RPS6KB1	S3	G9D	9	Missense	distal	6	no	26.508	25.026	EPSD	COSMIC	24.279	Down-regulation
AGC_RSK_RSKp70_RPS6KB1_ST	P35568	IRS1	P23443	RPS6KB1	S270	R265C	265	Missense	distal	-5	no	44.958	35.725	EPSD;PhosphoSitePlus	COSMIC	24.279	Down-regulation
AGC_RSK_RSKp70_RPS6KB1_ST	P35568	IRS1	P23443	RPS6KB1	S270	S274P	274	Missense	distal	4	no	44.958	44.024	EPSD;PhosphoSitePlus	COSMIC	24.279	Down-regulation
AGC_RSK_RSKp70_RPS6KB1_ST	P35568	IRS1	P23443	RPS6KB1	S272	R265C	265	Missense	distal	-7	no	27.405	27.527	EPSD	COSMIC	24.279	Up-regulation
AGC_RSK_RSKp70_RPS6KB1_ST	P35568	IRS1	P23443	RPS6KB1	S272	S274P	274	Missense	proximal	2	no	27.405	25.052	EPSD	COSMIC	24.279	Down-regulation
AGC_RSK_RSKp70_RPS6KB1_ST	P35568	IRS1	P23443	RPS6KB1	T305	R301C	301	Missense	distal	-4	no	28.306	26.913	EPSD	COSMIC	24.279	Down-regulation
AGC_RSK_RSKp70_RPS6KB1_ST	P35568	IRS1	P23443	RPS6KB1	T305	E306K	306	Missense	proximal	1	no	28.306	26.724	EPSD	COSMIC	24.279	Down-regulation
AGC_RSK_RSKp70_RPS6KB1_ST	P35568	IRS1	P23443	RPS6KB1	T305	A310T	310	Missense	distal	5	no	28.306	29.149	EPSD	COSMIC	24.279	Up-regulation
AGC_RSK_RSKp70_RPS6KB1_ST	P35568	IRS1	P23443	RPS6KB1	T305	R302L	302	Missense	distal	-3	no	28.306	18.639	EPSD	COSMIC	24.279	Loss
AGC_RSK_RSKp70_RPS6KB1_ST	P35568	IRS1	P23443	RPS6KB1	T305	I308M	308	Missense	distal	3	no	28.306	29.343	EPSD	COSMIC	24.279	Up-regulation
AGC_RSK_RSKp70_RPS6KB1_ST	P35568	IRS1	P23443	RPS6KB1	T305	A310V	310	Missense	distal	5	no	28.306	27.642	EPSD	COSMIC	24.279	Down-regulation
AGC_RSK_RSKp70_RPS6KB1_ST	P35568	IRS1	P23443	RPS6KB1	S307	R301C	301	Missense	distal	-6	no	46.236	46.276	EPSD;PhosphoSitePlus	COSMIC	24.279	Up-regulation
AGC_RSK_RSKp70_RPS6KB1_ST	P35568	IRS1	P23443	RPS6KB1	S307	E306K	306	Missense	proximal	-1	no	46.236	46.299	EPSD;PhosphoSitePlus	COSMIC	24.279	Up-regulation
AGC_RSK_RSKp70_RPS6KB1_ST	P35568	IRS1	P23443	RPS6KB1	S307	A310T	310	Missense	distal	3	no	46.236	46.839	EPSD;PhosphoSitePlus	COSMIC	24.279	Up-regulation
AGC_RSK_RSKp70_RPS6KB1_ST	P35568	IRS1	P23443	RPS6KB1	S307	P313L	313	Missense	distal	6	no	46.236	47.055	EPSD;PhosphoSitePlus	COSMIC;GDSC;CCLE	24.279	Up-regulation
AGC_RSK_RSKp70_RPS6KB1_ST	P35568	IRS1	P23443	RPS6KB1	S307	R302L	302	Missense	distal	-5	no	46.236	37.611	EPSD;PhosphoSitePlus	COSMIC	24.279	Down-regulation
AGC_RSK_RSKp70_RPS6KB1_ST	P35568	IRS1	P23443	RPS6KB1	S307	I308M	308	Missense	proximal	1	no	46.236	45.731	EPSD;PhosphoSitePlus	COSMIC	24.279	Down-regulation
AGC_RSK_RSKp70_RPS6KB1_ST	P35568	IRS1	P23443	RPS6KB1	S307	A310V	310	Missense	distal	3	no	46.236	46.617	EPSD;PhosphoSitePlus	COSMIC	24.279	Up-regulation
AGC_RSK_RSKp70_RPS6KB1_ST	P35568	IRS1	P23443	RPS6KB1	T309	E306K	306	Missense	distal	-3	no	25.015	27.742	EPSD	COSMIC	24.279	Up-regulation
AGC_RSK_RSKp70_RPS6KB1_ST	P35568	IRS1	P23443	RPS6KB1	T309	A310T	310	Missense	proximal	1	no	25.015	26.133	EPSD	COSMIC	24.279	Up-regulation
AGC_RSK_RSKp70_RPS6KB1_ST	P35568	IRS1	P23443	RPS6KB1	T309	P313L	313	Missense	distal	4	no	25.015	25.501	EPSD	COSMIC;GDSC;CCLE	24.279	Up-regulation
AGC_RSK_RSKp70_RPS6KB1_ST	P35568	IRS1	P23443	RPS6KB1	T309	M316V	316	Missense	distal	7	no	25.015	24.544	EPSD	COSMIC	24.279	Down-regulation
AGC_RSK_RSKp70_RPS6KB1_ST	P35568	IRS1	P23443	RPS6KB1	T309	R302L	302	Missense	distal	-7	no	25.015	25.120	EPSD	COSMIC	24.279	Up-regulation
AGC_RSK_RSKp70_RPS6KB1_ST	P35568	IRS1	P23443	RPS6KB1	T309	M316I	316	Missense	distal	7	no	25.015	24.680	EPSD	COSMIC	24.279	Down-regulation
AGC_RSK_RSKp70_RPS6KB1_ST	P35568	IRS1	P23443	RPS6KB1	T309	A310V	310	Missense	proximal	1	no	25.015	26.068	EPSD	COSMIC	24.279	Up-regulation
AGC_RSK_RSKp70_RPS6KB1_ST	P35568	IRS1	P23443	RPS6KB1	S312	E306K	306	Missense	distal	-6	no	35.163	35.155	EPSD	COSMIC	24.279	Down-regulation
AGC_RSK_RSKp70_RPS6KB1_ST	P35568	IRS1	P23443	RPS6KB1	S312	A310T	310	Missense	proximal	-2	no	35.163	35.137	EPSD	COSMIC	24.279	Down-regulation
AGC_RSK_RSKp70_RPS6KB1_ST	P35568	IRS1	P23443	RPS6KB1	S312	P313L	313	Missense	proximal	1	no	35.163	35.249	EPSD	COSMIC;GDSC;CCLE	24.279	Up-regulation
AGC_RSK_RSKp70_RPS6KB1_ST	P35568	IRS1	P23443	RPS6KB1	S312	M316V	316	Missense	distal	4	no	35.163	34.645	EPSD	COSMIC	24.279	Down-regulation
AGC_RSK_RSKp70_RPS6KB1_ST	P35568	IRS1	P23443	RPS6KB1	S312	M316I	316	Missense	distal	4	no	35.163	34.670	EPSD	COSMIC	24.279	Down-regulation
AGC_RSK_RSKp70_RPS6KB1_ST	P35568	IRS1	P23443	RPS6KB1	S312	I308M	308	Missense	distal	-4	no	35.163	35.933	EPSD	COSMIC	24.279	Up-regulation
AGC_RSK_RSKp70_RPS6KB1_ST	P35568	IRS1	P23443	RPS6KB1	S312	A310V	310	Missense	proximal	-2	no	35.163	35.739	EPSD	COSMIC	24.279	Up-regulation
AGC_RSK_RSKp70_RPS6KB1_ST	P35568	IRS1	P23443	RPS6KB1	S330	R327L	327	Missense	distal	-3	no	34.184	24.517	EPSD	COSMIC	24.279	Down-regulation
AGC_RSK_RSKp70_RPS6KB1_ST	P35568	IRS1	P23443	RPS6KB1	S330	R325H	325	Missense	distal	-5	no	34.184	31.330	EPSD	COSMIC;CCLE	24.279	Down-regulation
AGC_RSK_RSKp70_RPS6KB1_ST	P35568	IRS1	P23443	RPS6KB1	S330	R327C	327	Missense	distal	-3	no	34.184	24.635	EPSD	COSMIC;CCLE	24.279	Down-regulation
AGC_RSK_RSKp70_RPS6KB1_ST	P35568	IRS1	P23443	RPS6KB1	S330	E333K	333	Missense	distal	3	no	34.184	33.410	EPSD	COSMIC	24.279	Down-regulation
AGC_RSK_RSKp70_RPS6KB1_ST	P35568	IRS1	P23443	RPS6KB1	S330	G332R	332	Missense	proximal	2	no	34.184	33.890	EPSD	COSMIC	24.279	Down-regulation
AGC_RSK_RSKp70_RPS6KB1_ST	P35568	IRS1	P23443	RPS6KB1	S330	R325C	325	Missense	distal	-5	no	34.184	24.952	EPSD	COSMIC	24.279	Down-regulation
AGC_RSK_RSKp70_RPS6KB1_ST	P35568	IRS1	P23443	RPS6KB1	S330	F324L	324	Missense	distal	-6	no	34.184	34.129	EPSD	COSMIC	24.279	Down-regulation
AGC_RSK_RSKp70_RPS6KB1_ST	P35568	IRS1	P23443	RPS6KB1	S337	G332R	332	Missense	distal	-5	no	19.841	27.085	EPSD	COSMIC	24.279	Gain
AGC_RSK_RSKp70_RPS6KB1_ST	P35568	IRS1	P23443	RPS6KB1	S341	S341L	341	Missense	central	0	yes	28.623	0.000	EPSD	COSMIC	24.279	Loss
AGC_RSK_RSKp70_RPS6KB1_ST	P35568	IRS1	P23443	RPS6KB1	S341	P346S	346	Missense	distal	5	no	28.623	30.557	EPSD	COSMIC	24.279	Up-regulation
AGC_RSK_RSKp70_RPS6KB1_ST	P35568	IRS1	P23443	RPS6KB1	S362	L369F	369	Missense	distal	7	no	27.313	25.949	EPSD	COSMIC	24.279	Down-regulation
AGC_RSK_RSKp70_RPS6KB1_ST	P35568	IRS1	P23443	RPS6KB1	S362	A356P	356	Missense	distal	-6	no	27.313	27.327	EPSD	COSMIC	24.279	Up-regulation
AGC_RSK_RSKp70_RPS6KB1_ST	P35568	IRS1	P23443	RPS6KB1	S362	R364Q	364	Missense	proximal	2	no	27.313	25.506	EPSD	COSMIC	24.279	Down-regulation
AGC_RSK_RSKp70_RPS6KB1_ST	P35568	IRS1	P23443	RPS6KB1	S362	R358Q	358	Missense	distal	-4	no	27.313	25.293	EPSD	COSMIC	24.279	Down-regulation
AGC_RSK_RSKp70_RPS6KB1_ST	P35568	IRS1	P23443	RPS6KB1	S362	G361S	361	Missense	proximal	-1	no	27.313	27.228	EPSD	COSMIC	24.279	Down-regulation
AGC_RSK_RSKp70_RPS6KB1_ST	P35568	IRS1	P23443	RPS6KB1	S372	L369F	369	Missense	distal	-3	no	31.118	27.631	EPSD	COSMIC	24.279	Down-regulation
AGC_RSK_RSKp70_RPS6KB1_ST	P35568	IRS1	P23443	RPS6KB1	S372	A379P	379	Missense	distal	7	no	31.118	30.957	EPSD	COSMIC	24.279	Down-regulation
AGC_RSK_RSKp70_RPS6KB1_ST	P35568	IRS1	P23443	RPS6KB1	S385	S383W	383	Missense	proximal	-2	no	22.883	24.446	EPSD	COSMIC	24.279	Gain
AGC_RSK_RSKp70_RPS6KB1_ST	P35568	IRS1	P23443	RPS6KB1	S391	S398G	398	Missense	distal	7	no	27.826	27.447	EPSD	COSMIC	24.279	Down-regulation
AGC_RSK_RSKp70_RPS6KB1_ST	P35568	IRS1	P23443	RPS6KB1	S391	S395I	395	Missense	distal	4	no	27.826	26.637	EPSD	COSMIC;GDSC;CCLE	24.279	Down-regulation
AGC_RSK_RSKp70_RPS6KB1_ST	P35568	IRS1	P23443	RPS6KB1	S391	P384S	384	Missense	distal	-7	no	27.826	27.615	EPSD	COSMIC	24.279	Down-regulation
AGC_RSK_RSKp70_RPS6KB1_ST	P35568	IRS1	P23443	RPS6KB1	S391	S385L	385	Missense	distal	-6	no	27.826	27.869	EPSD	COSMIC	24.279	Up-regulation
AGC_RSK_RSKp70_RPS6KB1_ST	P35568	IRS1	P23443	RPS6KB1	S396	S398G	398	Missense	proximal	2	no	26.269	24.460	EPSD	COSMIC	24.279	Down-regulation
AGC_RSK_RSKp70_RPS6KB1_ST	P35568	IRS1	P23443	RPS6KB1	S396	G401D	401	Missense	distal	5	no	26.269	24.846	EPSD	COSMIC	24.279	Down-regulation
AGC_RSK_RSKp70_RPS6KB1_ST	P35568	IRS1	P23443	RPS6KB1	S396	T403S	403	Missense	distal	7	no	26.269	26.934	EPSD	COSMIC	24.279	Up-regulation
AGC_RSK_RSKp70_RPS6KB1_ST	P35568	IRS1	P23443	RPS6KB1	S396	H400Q	400	Missense	distal	4	no	26.269	26.292	EPSD	COSMIC	24.279	Up-regulation
AGC_RSK_RSKp70_RPS6KB1_ST	P35568	IRS1	P23443	RPS6KB1	S396	S395I	395	Missense	proximal	-1	no	26.269	26.324	EPSD	COSMIC;GDSC;CCLE	24.279	Up-regulation
AGC_RSK_RSKp70_RPS6KB1_ST	P35568	IRS1	P23443	RPS6KB1	S398	S398G	398	Missense	central	0	yes	27.473	0.000	EPSD	COSMIC	24.279	Loss
AGC_RSK_RSKp70_RPS6KB1_ST	P35568	IRS1	P23443	RPS6KB1	S398	G401D	401	Missense	distal	3	no	27.473	30.110	EPSD	COSMIC	24.279	Up-regulation
AGC_RSK_RSKp70_RPS6KB1_ST	P35568	IRS1	P23443	RPS6KB1	S398	T403S	403	Missense	distal	5	no	27.473	28.357	EPSD	COSMIC	24.279	Up-regulation
AGC_RSK_RSKp70_RPS6KB1_ST	P35568	IRS1	P23443	RPS6KB1	S398	H400Q	400	Missense	proximal	2	no	27.473	25.145	EPSD	COSMIC	24.279	Down-regulation
AGC_RSK_RSKp70_RPS6KB1_ST	P35568	IRS1	P23443	RPS6KB1	S398	S395I	395	Missense	distal	-3	no	27.473	22.043	EPSD	COSMIC;GDSC;CCLE	24.279	Loss
AGC_RSK_RSKp70_RPS6KB1_ST	P35568	IRS1	P23443	RPS6KB1	S402	S398G	398	Missense	distal	-4	no	26.489	23.442	EPSD	COSMIC	24.279	Loss
AGC_RSK_RSKp70_RPS6KB1_ST	P35568	IRS1	P23443	RPS6KB1	S402	G401D	401	Missense	proximal	-1	no	26.489	26.509	EPSD	COSMIC	24.279	Up-regulation
AGC_RSK_RSKp70_RPS6KB1_ST	P35568	IRS1	P23443	RPS6KB1	S402	T403S	403	Missense	proximal	1	no	26.489	25.752	EPSD	COSMIC	24.279	Down-regulation
AGC_RSK_RSKp70_RPS6KB1_ST	P35568	IRS1	P23443	RPS6KB1	S402	H400Q	400	Missense	proximal	-2	no	26.489	27.362	EPSD	COSMIC	24.279	Up-regulation
AGC_RSK_RSKp70_RPS6KB1_ST	P35568	IRS1	P23443	RPS6KB1	S402	S395I	395	Missense	distal	-7	no	26.489	26.669	EPSD	COSMIC;GDSC;CCLE	24.279	Up-regulation
AGC_RSK_RSKp70_RPS6KB1_ST	P35568	IRS1	P23443	RPS6KB1	S415	S415L	415	Missense	central	0	yes	39.075	0.000	EPSD	COSMIC	24.279	Loss
AGC_RSK_RSKp70_RPS6KB1_ST	P35568	IRS1	P23443	RPS6KB1	S415	G418V	418	Missense	distal	3	no	39.075	41.002	EPSD	COSMIC;GDSC;CCLE	24.279	Up-regulation
AGC_RSK_RSKp70_RPS6KB1_ST	P35568	IRS1	P23443	RPS6KB1	S415	D422N	422	Missense	distal	7	no	39.075	39.394	EPSD	COSMIC	24.279	Up-regulation
AGC_RSK_RSKp70_RPS6KB1_ST	P35568	IRS1	P23443	RPS6KB1	S440	P435L	435	Missense	distal	-5	no	26.414	26.268	EPSD	COSMIC	24.279	Down-regulation
AGC_RSK_RSKp70_RPS6KB1_ST	P35568	IRS1	P23443	RPS6KB1	S440	R439Q	439	Missense	proximal	-1	no	26.414	26.443	EPSD	COSMIC	24.279	Up-regulation
AGC_RSK_RSKp70_RPS6KB1_ST	P35568	IRS1	P23443	RPS6KB1	S440	S441Y	441	Missense	proximal	1	no	26.414	27.778	EPSD	COSMIC	24.279	Up-regulation
AGC_RSK_RSKp70_RPS6KB1_ST	P35568	IRS1	P23443	RPS6KB1	S440	S434G	434	Missense	distal	-6	no	26.414	26.450	EPSD	COSMIC	24.279	Up-regulation
AGC_RSK_RSKp70_RPS6KB1_ST	P35568	IRS1	P23443	RPS6KB1	S440	S441F	441	Missense	proximal	1	no	26.414	27.963	EPSD	COSMIC	24.279	Up-regulation
AGC_RSK_RSKp70_RPS6KB1_ST	P35568	IRS1	P23443	RPS6KB1	S440	R443C	443	Missense	distal	3	no	26.414	24.744	EPSD	COSMIC	24.279	Down-regulation
AGC_RSK_RSKp70_RPS6KB1_ST	P35568	IRS1	P23443	RPS6KB1	S440	P435F	435	Missense	distal	-5	no	26.414	23.582	EPSD	COSMIC	24.279	Loss
AGC_RSK_RSKp70_RPS6KB1_ST	P35568	IRS1	P23443	RPS6KB1	S440	P447L	447	Missense	distal	7	no	26.414	26.372	EPSD	COSMIC	24.279	Down-regulation
AGC_RSK_RSKp70_RPS6KB1_ST	P35568	IRS1	P23443	RPS6KB1	S440	R443L	443	Missense	distal	3	no	26.414	26.282	EPSD	COSMIC	24.279	Down-regulation
AGC_RSK_RSKp70_RPS6KB1_ST	P35568	IRS1	P23443	RPS6KB1	S440	S444I	444	Missense	distal	4	no	26.414	25.226	EPSD	COSMIC	24.279	Down-regulation
AGC_RSK_RSKp70_RPS6KB1_ST	P35568	IRS1	P23443	RPS6KB1	S444	G451C	451	Missense	distal	7	no	29.880	28.724	EPSD	COSMIC	24.279	Down-regulation
AGC_RSK_RSKp70_RPS6KB1_ST	P35568	IRS1	P23443	RPS6KB1	S444	R439Q	439	Missense	distal	-5	no	29.880	17.905	EPSD	COSMIC	24.279	Loss
AGC_RSK_RSKp70_RPS6KB1_ST	P35568	IRS1	P23443	RPS6KB1	S444	D448E	448	Missense	distal	4	no	29.880	29.787	EPSD	COSMIC	24.279	Down-regulation
AGC_RSK_RSKp70_RPS6KB1_ST	P35568	IRS1	P23443	RPS6KB1	S444	S441Y	441	Missense	distal	-3	no	29.880	22.525	EPSD	COSMIC	24.279	Loss
AGC_RSK_RSKp70_RPS6KB1_ST	P35568	IRS1	P23443	RPS6KB1	S444	S441F	441	Missense	distal	-3	no	29.880	26.210	EPSD	COSMIC	24.279	Down-regulation
AGC_RSK_RSKp70_RPS6KB1_ST	P35568	IRS1	P23443	RPS6KB1	S444	R443C	443	Missense	proximal	-1	no	29.880	29.953	EPSD	COSMIC	24.279	Up-regulation
AGC_RSK_RSKp70_RPS6KB1_ST	P35568	IRS1	P23443	RPS6KB1	S444	P447L	447	Missense	distal	3	no	29.880	30.720	EPSD	COSMIC	24.279	Up-regulation
AGC_RSK_RSKp70_RPS6KB1_ST	P35568	IRS1	P23443	RPS6KB1	S444	R443L	443	Missense	proximal	-1	no	29.880	29.900	EPSD	COSMIC	24.279	Up-regulation
AGC_RSK_RSKp70_RPS6KB1_ST	P35568	IRS1	P23443	RPS6KB1	S444	S444I	444	Missense	central	0	yes	29.880	0.000	EPSD	COSMIC	24.279	Loss
AGC_RSK_RSKp70_RPS6KB1_ST	P35568	IRS1	P23443	RPS6KB1	S444	S449P	449	Missense	distal	5	no	29.880	27.945	EPSD	COSMIC	24.279	Down-regulation
AGC_RSK_RSKp70_RPS6KB1_ST	P35568	IRS1	P23443	RPS6KB1	T446	G451C	451	Missense	distal	5	no	26.985	24.725	EPSD	COSMIC	24.279	Down-regulation
AGC_RSK_RSKp70_RPS6KB1_ST	P35568	IRS1	P23443	RPS6KB1	T446	R439Q	439	Missense	distal	-7	no	26.985	27.055	EPSD	COSMIC	24.279	Up-regulation
AGC_RSK_RSKp70_RPS6KB1_ST	P35568	IRS1	P23443	RPS6KB1	T446	D448E	448	Missense	proximal	2	no	26.985	27.671	EPSD	COSMIC	24.279	Up-regulation
AGC_RSK_RSKp70_RPS6KB1_ST	P35568	IRS1	P23443	RPS6KB1	T446	S441Y	441	Missense	distal	-5	no	26.985	22.281	EPSD	COSMIC	24.279	Loss
AGC_RSK_RSKp70_RPS6KB1_ST	P35568	IRS1	P23443	RPS6KB1	T446	T453I	453	Missense	distal	7	no	26.985	26.869	EPSD	COSMIC	24.279	Down-regulation
AGC_RSK_RSKp70_RPS6KB1_ST	P35568	IRS1	P23443	RPS6KB1	T446	S441F	441	Missense	distal	-5	no	26.985	21.214	EPSD	COSMIC	24.279	Loss
AGC_RSK_RSKp70_RPS6KB1_ST	P35568	IRS1	P23443	RPS6KB1	T446	R443C	443	Missense	distal	-3	no	26.985	17.436	EPSD	COSMIC	24.279	Loss
AGC_RSK_RSKp70_RPS6KB1_ST	P35568	IRS1	P23443	RPS6KB1	T446	P447L	447	Missense	proximal	1	no	26.985	27.072	EPSD	COSMIC	24.279	Up-regulation
AGC_RSK_RSKp70_RPS6KB1_ST	P35568	IRS1	P23443	RPS6KB1	T446	R443L	443	Missense	distal	-3	no	26.985	17.318	EPSD	COSMIC	24.279	Loss
AGC_RSK_RSKp70_RPS6KB1_ST	P35568	IRS1	P23443	RPS6KB1	T446	S444I	444	Missense	proximal	-2	no	26.985	28.048	EPSD	COSMIC	24.279	Up-regulation
AGC_RSK_RSKp70_RPS6KB1_ST	P35568	IRS1	P23443	RPS6KB1	T446	S449P	449	Missense	distal	3	no	26.985	24.446	EPSD	COSMIC	24.279	Down-regulation
AGC_RSK_RSKp70_RPS6KB1_ST	P35568	IRS1	P23443	RPS6KB1	T498	T495A	495	Missense	distal	-3	no	28.427	28.458	EPSD	COSMIC	24.279	Up-regulation
AGC_RSK_RSKp70_RPS6KB1_ST	P35568	IRS1	P23443	RPS6KB1	T498	G497E	497	Missense	proximal	-1	no	28.427	28.348	EPSD	COSMIC	24.279	Down-regulation
AGC_RSK_RSKp70_RPS6KB1_ST	P35568	IRS1	P23443	RPS6KB1	T498	H492Y	492	Missense	distal	-6	no	28.427	28.488	EPSD	COSMIC	24.279	Up-regulation
AGC_RSK_RSKp70_RPS6KB1_ST	P35568	IRS1	P23443	RPS6KB1	T525	T530A	530	Missense	distal	5	no	28.631	27.788	EPSD	COSMIC	24.279	Down-regulation
AGC_RSK_RSKp70_RPS6KB1_ST	P35568	IRS1	P23443	RPS6KB1	T525	R520L	520	Missense	distal	-5	no	28.631	20.007	EPSD	COSMIC	24.279	Loss
AGC_RSK_RSKp70_RPS6KB1_ST	P35568	IRS1	P23443	RPS6KB1	T525	F521I	521	Missense	distal	-4	no	28.631	30.397	EPSD	COSMIC	24.279	Up-regulation
AGC_RSK_RSKp70_RPS6KB1_ST	P35568	IRS1	P23443	RPS6KB1	T525	H526Y	526	Missense	proximal	1	no	28.631	29.612	EPSD	COSMIC	24.279	Up-regulation
AGC_RSK_RSKp70_RPS6KB1_ST	P35568	IRS1	P23443	RPS6KB1	T525	G529D	529	Missense	distal	4	no	28.631	29.140	EPSD	COSMIC	24.279	Up-regulation
AGC_RSK_RSKp70_RPS6KB1_ST	P35568	IRS1	P23443	RPS6KB1	S527	T530A	530	Missense	distal	3	no	36.607	36.004	EPSD;PhosphoSitePlus	COSMIC	24.279	Down-regulation
AGC_RSK_RSKp70_RPS6KB1_ST	P35568	IRS1	P23443	RPS6KB1	S527	R520L	520	Missense	distal	-7	no	36.607	36.712	EPSD;PhosphoSitePlus	COSMIC	24.279	Up-regulation
AGC_RSK_RSKp70_RPS6KB1_ST	P35568	IRS1	P23443	RPS6KB1	S527	T533I	533	Missense	distal	6	no	36.607	35.415	EPSD;PhosphoSitePlus	COSMIC	24.279	Down-regulation
AGC_RSK_RSKp70_RPS6KB1_ST	P35568	IRS1	P23443	RPS6KB1	S527	F521I	521	Missense	distal	-6	no	36.607	36.570	EPSD;PhosphoSitePlus	COSMIC	24.279	Down-regulation
AGC_RSK_RSKp70_RPS6KB1_ST	P35568	IRS1	P23443	RPS6KB1	S527	H526Y	526	Missense	proximal	-1	no	36.607	36.587	EPSD;PhosphoSitePlus	COSMIC	24.279	Down-regulation
AGC_RSK_RSKp70_RPS6KB1_ST	P35568	IRS1	P23443	RPS6KB1	S527	G529D	529	Missense	proximal	2	no	36.607	34.919	EPSD;PhosphoSitePlus	COSMIC	24.279	Down-regulation
AGC_RSK_RSKp70_RPS6KB1_ST	P35568	IRS1	P23443	RPS6KB1	S574	F576L	576	Missense	proximal	2	no	22.115	26.139	EPSD	COSMIC	24.279	Gain
AGC_RSK_RSKp70_RPS6KB1_ST	P35568	IRS1	P23443	RPS6KB1	S603	H598R	598	Missense	distal	-5	no	29.002	31.857	EPSD	COSMIC	24.279	Up-regulation
AGC_RSK_RSKp70_RPS6KB1_ST	P35568	IRS1	P23443	RPS6KB1	S603	G596E	596	Missense	distal	-7	no	29.002	28.777	EPSD	COSMIC	24.279	Down-regulation
AGC_RSK_RSKp70_RPS6KB1_ST	P35568	IRS1	P23443	RPS6KB1	S603	H599Y	599	Missense	distal	-4	no	29.002	29.492	EPSD	COSMIC	24.279	Up-regulation
AGC_RSK_RSKp70_RPS6KB1_ST	P35568	IRS1	P23443	RPS6KB1	S603	H599Q	599	Missense	distal	-4	no	29.002	27.437	EPSD	COSMIC	24.279	Down-regulation
AGC_RSK_RSKp70_RPS6KB1_ST	P35568	IRS1	P23443	RPS6KB1	S604	H598R	598	Missense	distal	-6	no	24.894	24.880	EPSD	COSMIC	24.279	Down-regulation
AGC_RSK_RSKp70_RPS6KB1_ST	P35568	IRS1	P23443	RPS6KB1	S604	H599Y	599	Missense	distal	-5	no	24.894	17.505	EPSD	COSMIC	24.279	Loss
AGC_RSK_RSKp70_RPS6KB1_ST	P35568	IRS1	P23443	RPS6KB1	S604	H599Q	599	Missense	distal	-5	no	24.894	15.774	EPSD	COSMIC	24.279	Loss
AGC_RSK_RSKp70_RPS6KB1_ST	P35568	IRS1	P23443	RPS6KB1	T605	H598R	598	Missense	distal	-7	no	27.836	27.781	EPSD	COSMIC	24.279	Down-regulation
AGC_RSK_RSKp70_RPS6KB1_ST	P35568	IRS1	P23443	RPS6KB1	T605	H599Y	599	Missense	distal	-6	no	27.836	27.897	EPSD	COSMIC	24.279	Up-regulation
AGC_RSK_RSKp70_RPS6KB1_ST	P35568	IRS1	P23443	RPS6KB1	T605	H599Q	599	Missense	distal	-6	no	27.836	27.856	EPSD	COSMIC	24.279	Up-regulation
AGC_RSK_RSKp70_RPS6KB1_ST	P35568	IRS1	P23443	RPS6KB1	S616	V622M	622	Missense	distal	6	no	35.731	36.006	EPSD	COSMIC	24.279	Up-regulation
AGC_RSK_RSKp70_RPS6KB1_ST	P35568	IRS1	P23443	RPS6KB1	S616	P614A	614	Missense	proximal	-2	no	35.731	34.901	EPSD	COSMIC;CCLE	24.279	Down-regulation
AGC_RSK_RSKp70_RPS6KB1_ST	P35568	IRS1	P23443	RPS6KB1	S636	V640I	640	Missense	distal	4	no	36.942	36.967	PhosphoSitePlus;EPSD	COSMIC;GDSC;CCLE	24.279	Up-regulation
AGC_RSK_RSKp70_RPS6KB1_ST	P35568	IRS1	P23443	RPS6KB1	S636	A642T	642	Missense	distal	6	no	36.942	38.130	PhosphoSitePlus;EPSD	COSMIC	24.279	Up-regulation
AGC_RSK_RSKp70_RPS6KB1_ST	P35568	IRS1	P23443	RPS6KB1	S636	G630E	630	Missense	distal	-6	no	36.942	36.924	PhosphoSitePlus;EPSD	COSMIC	24.279	Down-regulation
AGC_RSK_RSKp70_RPS6KB1_ST	P35568	IRS1	P23443	RPS6KB1	S639	V640I	640	Missense	proximal	1	no	35.291	35.327	EPSD	COSMIC;GDSC;CCLE	24.279	Up-regulation
AGC_RSK_RSKp70_RPS6KB1_ST	P35568	IRS1	P23443	RPS6KB1	S639	A642T	642	Missense	distal	3	no	35.291	35.894	EPSD	COSMIC	24.279	Up-regulation
AGC_RSK_RSKp70_RPS6KB1_ST	P35568	IRS1	P23443	RPS6KB1	S666	G669S	669	Missense	distal	3	no	23.172	27.166	EPSD	COSMIC	24.279	Gain
AGC_RSK_RSKp70_RPS6KB1_ST	P35568	IRS1	P23443	RPS6KB1	S668	G661D	661	Missense	distal	-7	no	24.578	24.618	EPSD	COSMIC	24.279	Up-regulation
AGC_RSK_RSKp70_RPS6KB1_ST	P35568	IRS1	P23443	RPS6KB1	S668	G669S	669	Missense	proximal	1	no	24.578	23.476	EPSD	COSMIC	24.279	Loss
AGC_RSK_RSKp70_RPS6KB1_ST	P35568	IRS1	P23443	RPS6KB1	S668	M664I	664	Missense	distal	-4	no	24.578	23.807	EPSD	COSMIC	24.279	Loss
AGC_RSK_RSKp70_RPS6KB1_ST	P35568	IRS1	P23443	RPS6KB1	S736	G739E	739	Missense	distal	3	no	22.317	26.545	EPSD	COSMIC	24.279	Gain
AGC_RSK_RSKp70_RPS6KB1_ST	P35568	IRS1	P23443	RPS6KB1	S763	S763A	763	Missense	central	0	yes	29.109	0.000	EPSD	COSMIC	24.279	Loss
AGC_RSK_RSKp70_RPS6KB1_ST	P35568	IRS1	P23443	RPS6KB1	S763	Q757K	757	Missense	distal	-6	no	29.109	29.079	EPSD	COSMIC	24.279	Down-regulation
AGC_RSK_RSKp70_RPS6KB1_ST	P35568	IRS1	P23443	RPS6KB1	S763	S766T	766	Missense	distal	3	no	29.109	27.263	EPSD	COSMIC	24.279	Down-regulation
AGC_RSK_RSKp70_RPS6KB1_ST	P35568	IRS1	P23443	RPS6KB1	S792	Q787R	787	Missense	distal	-5	no	17.087	29.062	EPSD	COSMIC	24.279	Gain
AGC_RSK_RSKp70_RPS6KB1_ST	P35568	IRS1	P23443	RPS6KB1	T793	S792F	792	Missense	proximal	-1	no	26.941	27.060	EPSD	COSMIC	24.279	Up-regulation
AGC_RSK_RSKp70_RPS6KB1_ST	P35568	IRS1	P23443	RPS6KB1	T793	R790C	790	Missense	distal	-3	no	26.941	17.392	EPSD	COSMIC	24.279	Loss
AGC_RSK_RSKp70_RPS6KB1_ST	P35568	IRS1	P23443	RPS6KB1	T793	Q787R	787	Missense	distal	-6	no	26.941	26.907	EPSD	COSMIC	24.279	Down-regulation
AGC_RSK_RSKp70_RPS6KB1_ST	P35568	IRS1	P23443	RPS6KB1	S862	T859M	859	Missense	distal	-3	no	22.015	26.467	EPSD	COSMIC	24.279	Gain
AGC_RSK_RSKp70_RPS6KB1_ST	P35568	IRS1	P23443	RPS6KB1	S995	P997S	997	Missense	proximal	2	no	23.429	25.782	EPSD	COSMIC	24.279	Gain
AGC_RSK_RSKp70_RPS6KB1_ST	P35568	IRS1	P23443	RPS6KB1	S1101	R1097W	1097	Missense	distal	-4	no	49.169	47.489	EPSD;PhosphoSitePlus	COSMIC	24.279	Down-regulation
AGC_RSK_RSKp70_RPS6KB1_ST	P35568	IRS1	P23443	RPS6KB1	S1101	E1102K	1102	Missense	proximal	1	no	49.169	47.587	EPSD;PhosphoSitePlus	COSMIC	24.279	Down-regulation
AGC_RSK_RSKp70_RPS6KB1_ST	P35568	IRS1	P23443	RPS6KB1	T1103	R1097W	1097	Missense	distal	-6	no	30.220	30.283	EPSD	COSMIC	24.279	Up-regulation
AGC_RSK_RSKp70_RPS6KB1_ST	P35568	IRS1	P23443	RPS6KB1	T1103	E1102K	1102	Missense	proximal	-1	no	30.220	30.284	EPSD	COSMIC	24.279	Up-regulation
AGC_RSK_RSKp70_RPS6KB1_ST	P35568	IRS1	P23443	RPS6KB1	S1105	E1102K	1102	Missense	distal	-3	no	32.740	35.467	EPSD	COSMIC	24.279	Up-regulation
AGC_RSK_RSKp70_RPS6KB1_ST	P35568	IRS1	P23443	RPS6KB1	S1106	E1102K	1102	Missense	distal	-4	no	27.271	28.663	EPSD	COSMIC	24.279	Up-regulation
AGC_RSK_RSKp70_RPS6KB1_ST	P35568	IRS1	P23443	RPS6KB1	S1133	G1128S	1128	Missense	distal	-5	no	22.890	24.595	EPSD	COSMIC	24.279	Gain
AGC_RSK_RSKp70_RPS6KB1_ST	P35568	IRS1	P23443	RPS6KB1	S1143	R1140C	1140	Missense	distal	-3	no	34.193	24.644	EPSD	COSMIC;CCLE	24.279	Down-regulation
AGC_RSK_RSKp70_RPS6KB1_ST	P35568	IRS1	P23443	RPS6KB1	S1216	G1212V	1212	Missense	distal	-4	no	23.886	24.823	EPSD	COSMIC	24.279	Gain
AGC_RSK_RSKp70_RPS6KB1_ST	Q15633	TARBP2	P23443	RPS6KB1	S112	P113L	113	Missense	proximal	1	no	27.759	27.846	EPSD	COSMIC	24.279	Up-regulation
AGC_RSK_RSKp70_RPS6KB1_ST	Q15633	TARBP2	P23443	RPS6KB1	T179	Q182R	182	Missense	distal	3	no	27.098	28.424	EPSD	COSMIC	24.279	Up-regulation
AGC_RSK_RSKp70_RPS6KB1_ST	Q15633	TARBP2	P23443	RPS6KB1	T179	T179I	179	Missense	central	0	yes	27.098	0.000	EPSD	COSMIC;GDSC	24.279	Loss
AGC_RSK_RSKp70_RPS6KB1_ST	Q15633	TARBP2	P23443	RPS6KB1	S246	R252H	252	Missense	distal	6	no	24.770	25.165	EPSD	COSMIC	24.279	Up-regulation
AGC_RSK_RSKp70_RPS6KB1_ST	Q15633	TARBP2	P23443	RPS6KB1	S246	F245I	245	Missense	proximal	-1	no	24.770	24.705	EPSD	COSMIC	24.279	Down-regulation
AGC_RSK_RSKp70_RPS6KB1_ST	Q15633	TARBP2	P23443	RPS6KB1	S281	I276T	276	Missense	distal	-5	no	21.324	24.888	EPSD	COSMIC	24.279	Gain
AGC_RSK_RSKp70_RPS6KB1_ST	Q15633	TARBP2	P23443	RPS6KB1	S283	I276T	276	Missense	distal	-7	no	39.175	39.049	PhosphoSitePlus	COSMIC	24.279	Down-regulation
AGC_RSK_RSKp70_RPS6KB1_ST	Q15633	TARBP2	P23443	RPS6KB1	S283	S278Y	278	Missense	distal	-5	no	39.175	34.470	PhosphoSitePlus	COSMIC	24.279	Down-regulation
AGC_RSK_RSKp70_RPS6KB1_ST	Q15633	TARBP2	P23443	RPS6KB1	S283	L279I	279	Missense	distal	-4	no	39.175	39.067	PhosphoSitePlus	COSMIC	24.279	Down-regulation
AGC_RSK_RSKp70_RPS6KB1_ST	P42345	MTOR	P23443	RPS6KB1	T15	A12T	12	Missense	distal	-3	no	26.287	26.256	EPSD	COSMIC	24.279	Down-regulation
AGC_RSK_RSKp70_RPS6KB1_ST	P42345	MTOR	P23443	RPS6KB1	T15	T10A	10	Missense	distal	-5	no	26.287	26.151	EPSD	COSMIC	24.279	Down-regulation
AGC_RSK_RSKp70_RPS6KB1_ST	P42345	MTOR	P23443	RPS6KB1	T714	G716S	716	Missense	proximal	2	no	25.169	26.978	EPSD	COSMIC	24.279	Up-regulation
AGC_RSK_RSKp70_RPS6KB1_ST	P42345	MTOR	P23443	RPS6KB1	T714	R717L	717	Missense	distal	3	no	25.169	25.037	EPSD	COSMIC	24.279	Down-regulation
AGC_RSK_RSKp70_RPS6KB1_ST	P42345	MTOR	P23443	RPS6KB1	T714	V715M	715	Missense	proximal	1	no	25.169	24.700	EPSD	COSMIC	24.279	Down-regulation
AGC_RSK_RSKp70_RPS6KB1_ST	P42345	MTOR	P23443	RPS6KB1	T714	A711T	711	Missense	distal	-3	no	25.169	25.138	EPSD	COSMIC	24.279	Down-regulation
AGC_RSK_RSKp70_RPS6KB1_ST	P42345	MTOR	P23443	RPS6KB1	T714	I712L	712	Missense	proximal	-2	no	25.169	24.248	EPSD	COSMIC	24.279	Loss
AGC_RSK_RSKp70_RPS6KB1_ST	P42345	MTOR	P23443	RPS6KB1	T714	R708Q	708	Missense	distal	-6	no	25.169	25.203	EPSD	COSMIC	24.279	Up-regulation
AGC_RSK_RSKp70_RPS6KB1_ST	P42345	MTOR	P23443	RPS6KB1	T714	G716D	716	Missense	proximal	2	no	25.169	23.480	EPSD	COSMIC	24.279	Loss
AGC_RSK_RSKp70_RPS6KB1_ST	P42345	MTOR	P23443	RPS6KB1	T714	S720I	720	Missense	distal	6	no	25.169	24.045	EPSD	COSMIC	24.279	Loss
AGC_RSK_RSKp70_RPS6KB1_ST	P42345	MTOR	P23443	RPS6KB1	S720	V715M	715	Missense	distal	-5	no	19.044	24.460	EPSD	COSMIC	24.279	Gain
AGC_RSK_RSKp70_RPS6KB1_ST	P42345	MTOR	P23443	RPS6KB1	S831	A835T	835	Missense	distal	4	no	25.316	25.070	EPSD	COSMIC	24.279	Down-regulation
AGC_RSK_RSKp70_RPS6KB1_ST	P42345	MTOR	P23443	RPS6KB1	S831	D826Y	826	Missense	distal	-5	no	25.316	23.562	EPSD	COSMIC	24.279	Loss
AGC_RSK_RSKp70_RPS6KB1_ST	P42345	MTOR	P23443	RPS6KB1	S831	D830G	830	Missense	proximal	-1	no	25.316	25.296	EPSD	COSMIC	24.279	Down-regulation
AGC_RSK_RSKp70_RPS6KB1_ST	P42345	MTOR	P23443	RPS6KB1	S831	D830H	830	Missense	proximal	-1	no	25.316	25.257	EPSD	COSMIC	24.279	Down-regulation
AGC_RSK_RSKp70_RPS6KB1_ST	P42345	MTOR	P23443	RPS6KB1	S831	L828F	828	Missense	distal	-3	no	25.316	21.830	EPSD	COSMIC	24.279	Loss
AGC_RSK_RSKp70_RPS6KB1_ST	P42345	MTOR	P23443	RPS6KB1	T880	T874S	874	Missense	distal	-6	no	25.228	25.208	EPSD	COSMIC	24.279	Down-regulation
AGC_RSK_RSKp70_RPS6KB1_ST	P42345	MTOR	P23443	RPS6KB1	T880	Q878E	878	Missense	proximal	-2	no	25.228	25.068	EPSD	COSMIC	24.279	Down-regulation
AGC_RSK_RSKp70_RPS6KB1_ST	P42345	MTOR	P23443	RPS6KB1	T880	R886C	886	Missense	distal	6	no	25.228	24.801	EPSD	COSMIC	24.279	Down-regulation
AGC_RSK_RSKp70_RPS6KB1_ST	P42345	MTOR	P23443	RPS6KB1	T880	K873N	873	Missense	distal	-7	no	25.228	25.247	EPSD	COSMIC	24.279	Up-regulation
AGC_RSK_RSKp70_RPS6KB1_ST	P42345	MTOR	P23443	RPS6KB1	T880	T880A	880	Missense	central	0	yes	25.228	0.000	EPSD	COSMIC	24.279	Loss
AGC_RSK_RSKp70_RPS6KB1_ST	P42345	MTOR	P23443	RPS6KB1	T880	E875K	875	Missense	distal	-5	no	25.228	24.035	EPSD	COSMIC	24.279	Loss
AGC_RSK_RSKp70_RPS6KB1_ST	P42345	MTOR	P23443	RPS6KB1	S913	D911Y	911	Missense	proximal	-2	no	25.034	24.307	EPSD	COSMIC	24.279	Down-regulation
AGC_RSK_RSKp70_RPS6KB1_ST	P42345	MTOR	P23443	RPS6KB1	S913	D907N	907	Missense	distal	-6	no	25.034	24.997	EPSD	COSMIC	24.279	Down-regulation
AGC_RSK_RSKp70_RPS6KB1_ST	P42345	MTOR	P23443	RPS6KB1	S1178	S1179L	1179	Missense	proximal	1	no	23.561	24.665	EPSD	COSMIC	24.279	Gain
AGC_RSK_RSKp70_RPS6KB1_ST	P42345	MTOR	P23443	RPS6KB1	S1178	F1182S	1182	Missense	distal	4	no	23.561	25.722	EPSD	COSMIC	24.279	Gain
AGC_RSK_RSKp70_RPS6KB1_ST	P42345	MTOR	P23443	RPS6KB1	S1179	F1182S	1182	Missense	distal	3	no	21.621	25.010	EPSD	COSMIC	24.279	Gain
AGC_RSK_RSKp70_RPS6KB1_ST	P42345	MTOR	P23443	RPS6KB1	S1288	L1292M	1292	Missense	distal	4	no	27.055	26.807	EPSD	COSMIC	24.279	Down-regulation
AGC_RSK_RSKp70_RPS6KB1_ST	P42345	MTOR	P23443	RPS6KB1	S1288	R1286Q	1286	Missense	proximal	-2	no	27.055	27.858	EPSD	COSMIC	24.279	Up-regulation
AGC_RSK_RSKp70_RPS6KB1_ST	P42345	MTOR	P23443	RPS6KB1	S1288	S1295L	1295	Missense	distal	7	no	27.055	26.539	EPSD	COSMIC	24.279	Down-regulation
AGC_RSK_RSKp70_RPS6KB1_ST	P42345	MTOR	P23443	RPS6KB1	S1296	S1297L	1297	Missense	proximal	1	no	27.084	28.188	EPSD	COSMIC	24.279	Up-regulation
AGC_RSK_RSKp70_RPS6KB1_ST	P42345	MTOR	P23443	RPS6KB1	S1296	R1301C	1301	Missense	distal	5	no	27.084	25.584	EPSD	COSMIC	24.279	Down-regulation
AGC_RSK_RSKp70_RPS6KB1_ST	P42345	MTOR	P23443	RPS6KB1	S1296	L1292M	1292	Missense	distal	-4	no	27.084	27.746	EPSD	COSMIC	24.279	Up-regulation
AGC_RSK_RSKp70_RPS6KB1_ST	P42345	MTOR	P23443	RPS6KB1	S1296	S1295L	1295	Missense	proximal	-1	no	27.084	27.133	EPSD	COSMIC	24.279	Up-regulation
AGC_RSK_RSKp70_RPS6KB1_ST	P42345	MTOR	P23443	RPS6KB1	S1418	E1414K	1414	Missense	distal	-4	no	23.040	24.432	EPSD	COSMIC	24.279	Gain
AGC_RSK_RSKp70_RPS6KB1_ST	P42345	MTOR	P23443	RPS6KB1	S1849	T1844S	1844	Missense	distal	-5	no	24.227	26.293	EPSD	COSMIC	24.279	Gain
AGC_RSK_RSKp70_RPS6KB1_ST	P42345	MTOR	P23443	RPS6KB1	S1855	E1850D	1850	Missense	distal	-5	no	30.105	26.215	EPSD	COSMIC	24.279	Down-regulation
AGC_RSK_RSKp70_RPS6KB1_ST	P42345	MTOR	P23443	RPS6KB1	T1861	P1864L	1864	Missense	distal	3	no	23.472	24.312	EPSD	COSMIC	24.279	Gain
AGC_RSK_RSKp70_RPS6KB1_ST	P42345	MTOR	P23443	RPS6KB1	S1893	F1888I	1888	Missense	distal	-5	no	24.886	25.028	EPSD	COSMIC	24.279	Up-regulation
AGC_RSK_RSKp70_RPS6KB1_ST	P42345	MTOR	P23443	RPS6KB1	S1893	L1894F	1894	Missense	proximal	1	no	24.886	25.331	EPSD	COSMIC	24.279	Up-regulation
AGC_RSK_RSKp70_RPS6KB1_ST	P42345	MTOR	P23443	RPS6KB1	S1893	F1889V	1889	Missense	distal	-4	no	24.886	25.402	EPSD	COSMIC	24.279	Up-regulation
AGC_RSK_RSKp70_RPS6KB1_ST	P42345	MTOR	P23443	RPS6KB1	S1893	N1899D	1899	Missense	distal	6	no	24.886	25.026	EPSD	COSMIC	24.279	Up-regulation
AGC_RSK_RSKp70_RPS6KB1_ST	P42345	MTOR	P23443	RPS6KB1	S1893	F1889Y	1889	Missense	distal	-4	no	24.886	26.490	EPSD	COSMIC	24.279	Up-regulation
AGC_RSK_RSKp70_RPS6KB1_ST	P42345	MTOR	P23443	RPS6KB1	S2069	R2076L	2076	Missense	distal	7	no	29.073	29.090	EPSD	COSMIC	24.279	Up-regulation
AGC_RSK_RSKp70_RPS6KB1_ST	P42345	MTOR	P23443	RPS6KB1	S2069	P2062L	2062	Missense	distal	-7	no	29.073	29.009	EPSD	COSMIC	24.279	Down-regulation
AGC_RSK_RSKp70_RPS6KB1_ST	P42345	MTOR	P23443	RPS6KB1	S2069	A2073V	2073	Missense	distal	4	no	29.073	28.363	EPSD	COSMIC	24.279	Down-regulation
AGC_RSK_RSKp70_RPS6KB1_ST	P42345	MTOR	P23443	RPS6KB1	S2069	Q2072H	2072	Missense	distal	3	no	29.073	30.007	EPSD	COSMIC	24.279	Up-regulation
AGC_RSK_RSKp70_RPS6KB1_ST	P42345	MTOR	P23443	RPS6KB1	S2069	Q2072R	2072	Missense	distal	3	no	29.073	30.400	EPSD	COSMIC;GDSC	24.279	Up-regulation
AGC_RSK_RSKp70_RPS6KB1_ST	P42345	MTOR	P23443	RPS6KB1	T2446	D2447N	2447	Missense	proximal	1	no	37.773	36.779	PhosphoSitePlus;EPSD	COSMIC	24.279	Down-regulation
AGC_RSK_RSKp70_RPS6KB1_ST	P42345	MTOR	P23443	RPS6KB1	T2446	T2446M	2446	Missense	central	0	yes	37.773	0.000	PhosphoSitePlus;EPSD	COSMIC	24.279	Loss
AGC_RSK_RSKp70_RPS6KB1_ST	P42345	MTOR	P23443	RPS6KB1	S2448	D2447N	2447	Missense	proximal	-1	no	38.831	38.799	EPSD;PhosphoSitePlus	COSMIC	24.279	Down-regulation
AGC_RSK_RSKp70_RPS6KB1_ST	P42345	MTOR	P23443	RPS6KB1	S2448	T2446M	2446	Missense	proximal	-2	no	38.831	38.463	EPSD;PhosphoSitePlus	COSMIC	24.279	Down-regulation
AGC_RSK_RSKp70_RPS6KB1_ST	P42345	MTOR	P23443	RPS6KB1	S2450	D2447N	2447	Missense	distal	-3	no	23.040	25.540	EPSD	COSMIC	24.279	Gain
AGC_RSK_RSKp70_RPS6KB1_ST	P42345	MTOR	P23443	RPS6KB1	S2514	D2516N	2516	Missense	proximal	2	no	25.147	25.141	EPSD	COSMIC	24.279	Down-regulation
AGC_RSK_RSKp70_RPS6KB1_ST	P42345	MTOR	P23443	RPS6KB1	S2514	D2512H	2512	Missense	proximal	-2	no	25.147	24.051	EPSD	COSMIC	24.279	Loss
AGC_RSK_RSKp70_RPS6KB1_ST	P42345	MTOR	P23443	RPS6KB1	S2514	R2511W	2511	Missense	distal	-3	no	25.147	10.131	EPSD	COSMIC	24.279	Loss
AGC_RSK_RSKp70_RPS6KB1_ST	P42345	MTOR	P23443	RPS6KB1	S2514	D2517G	2517	Missense	distal	3	no	25.147	22.510	EPSD	COSMIC	24.279	Loss
AGC_RSK_RSKp70_RPS6KB1_ST	P42345	MTOR	P23443	RPS6KB1	S2514	K2507R	2507	Missense	distal	-7	no	25.147	25.135	EPSD	COSMIC	24.279	Down-regulation
AGC_RSK_RSKp70_RPS6KB1_ST	Q06787	FMR1	P23443	RPS6KB1	S191	S197Y	197	Missense	distal	6	no	30.707	29.229	EPSD	COSMIC;GDSC;CCLE	24.279	Down-regulation
AGC_RSK_RSKp70_RPS6KB1_ST	Q06787	FMR1	P23443	RPS6KB1	S191	K195N	195	Missense	distal	4	no	30.707	29.922	EPSD	COSMIC	24.279	Down-regulation
AGC_RSK_RSKp70_RPS6KB1_ST	Q06787	FMR1	P23443	RPS6KB1	S191	R190W	190	Missense	proximal	-1	no	30.707	30.760	EPSD	COSMIC	24.279	Up-regulation
AGC_RSK_RSKp70_RPS6KB1_ST	Q06787	FMR1	P23443	RPS6KB1	S191	D186G	186	Missense	distal	-5	no	30.707	31.953	EPSD	COSMIC	24.279	Up-regulation
AGC_RSK_RSKp70_RPS6KB1_ST	Q06787	FMR1	P23443	RPS6KB1	S460	R454S	454	Missense	distal	-6	no	28.019	28.012	EPSD	COSMIC	24.279	Down-regulation
AGC_RSK_RSKp70_RPS6KB1_ST	Q06787	FMR1	P23443	RPS6KB1	S500	R507T	507	Missense	distal	7	no	34.017	33.885	PhosphoSitePlus	COSMIC	24.279	Down-regulation
AGC_RSK_RSKp70_RPS6KB1_ST	Q06787	FMR1	P23443	RPS6KB1	S500	H506N	506	Missense	distal	6	no	34.017	32.742	PhosphoSitePlus	COSMIC	24.279	Down-regulation
AGC_RSK_RSKp70_RPS6KB1_ST	Q06787	FMR1	P23443	RPS6KB1	S500	E495G	495	Missense	distal	-5	no	34.017	31.372	PhosphoSitePlus	COSMIC	24.279	Down-regulation
AGC_RSK_RSKp70_RPS6KB1_ST	Q06787	FMR1	P23443	RPS6KB1	T598	S599Y	599	Missense	proximal	1	no	26.450	27.814	EPSD	COSMIC	24.279	Up-regulation
AGC_RSK_RSKp70_RPS6KB1_ST	Q06787	FMR1	P23443	RPS6KB1	T598	H591N	591	Missense	distal	-7	no	26.450	26.427	EPSD	COSMIC	24.279	Down-regulation
AGC_RSK_RSKp70_RPS6KB1_ST	Q9UN36	NDRG2	P23443	RPS6KB1	S326	A331S	331	Missense	distal	5	no	22.558	24.286	EPSD	COSMIC	24.279	Gain
AGC_RSK_RSKp70_RPS6KB1_ST	Q9UN36	NDRG2	P23443	RPS6KB1	T330	S328F	328	Missense	proximal	-2	no	23.763	25.630	EPSD	COSMIC	24.279	Gain
AGC_RSK_RSKp70_RPS6KB1_ST	Q9UN36	NDRG2	P23443	RPS6KB1	T330	L325M	325	Missense	distal	-5	no	23.763	29.020	EPSD	COSMIC	24.279	Gain
AGC_RSK_RSKp70_RPS6KB1_ST	Q9UN36	NDRG2	P23443	RPS6KB1	S332	S328F	328	Missense	distal	-4	no	41.835	39.208	EPSD;PhosphoSitePlus	COSMIC	24.279	Down-regulation
AGC_RSK_RSKp70_RPS6KB1_ST	Q9UN36	NDRG2	P23443	RPS6KB1	S332	S338G	338	Missense	distal	6	no	41.835	42.001	EPSD;PhosphoSitePlus	COSMIC	24.279	Up-regulation
AGC_RSK_RSKp70_RPS6KB1_ST	Q9UN36	NDRG2	P23443	RPS6KB1	S332	S332F	332	Missense	central	0	yes	41.835	0.000	EPSD;PhosphoSitePlus	COSMIC	24.279	Loss
AGC_RSK_RSKp70_RPS6KB1_ST	Q9UN36	NDRG2	P23443	RPS6KB1	S332	A331S	331	Missense	proximal	-1	no	41.835	41.730	EPSD;PhosphoSitePlus	COSMIC	24.279	Down-regulation
AGC_RSK_RSKp70_RPS6KB1_ST	Q9UN36	NDRG2	P23443	RPS6KB1	S332	L325M	325	Missense	distal	-7	no	41.835	41.718	EPSD;PhosphoSitePlus	COSMIC	24.279	Down-regulation
AGC_RSK_RSKp70_RPS6KB1_ST	Q9UN36	NDRG2	P23443	RPS6KB1	S332	A337E	337	Missense	distal	5	no	41.835	42.173	EPSD;PhosphoSitePlus	COSMIC	24.279	Up-regulation
AGC_RSK_RSKp70_RPS6KB1_ST	Q9UN36	NDRG2	P23443	RPS6KB1	S344	S338G	338	Missense	distal	-6	no	27.128	27.164	EPSD	COSMIC	24.279	Up-regulation
AGC_RSK_RSKp70_RPS6KB1_ST	Q9UN36	NDRG2	P23443	RPS6KB1	S344	L349M	349	Missense	distal	5	no	27.128	25.464	EPSD	COSMIC	24.279	Down-regulation
AGC_RSK_RSKp70_RPS6KB1_ST	Q9UN36	NDRG2	P23443	RPS6KB1	S344	A337E	337	Missense	distal	-7	no	27.128	26.932	EPSD	COSMIC	24.279	Down-regulation
AGC_RSK_RSKp70_RPS6KB1_ST	Q9UN36	NDRG2	P23443	RPS6KB1	S344	R345L	345	Missense	proximal	1	no	27.128	27.442	EPSD	COSMIC	24.279	Up-regulation
AGC_RSK_RSKp70_RPS6KB1_ST	Q9UN36	NDRG2	P23443	RPS6KB1	S346	L349M	349	Missense	distal	3	no	30.746	31.673	EPSD	COSMIC	24.279	Up-regulation
AGC_RSK_RSKp70_RPS6KB1_ST	Q9UN36	NDRG2	P23443	RPS6KB1	S346	S353G	353	Missense	distal	7	no	30.746	30.368	EPSD	COSMIC	24.279	Down-regulation
AGC_RSK_RSKp70_RPS6KB1_ST	Q9UN36	NDRG2	P23443	RPS6KB1	S346	R345L	345	Missense	proximal	-1	no	30.746	30.766	EPSD	COSMIC	24.279	Up-regulation
AGC_RSK_RSKp70_RPS6KB1_ST	Q9UN36	NDRG2	P23443	RPS6KB1	T348	S355F	355	Missense	distal	7	no	34.565	32.685	EPSD	COSMIC	24.279	Down-regulation
AGC_RSK_RSKp70_RPS6KB1_ST	Q9UN36	NDRG2	P23443	RPS6KB1	T348	L349M	349	Missense	proximal	1	no	34.565	33.666	EPSD	COSMIC	24.279	Down-regulation
AGC_RSK_RSKp70_RPS6KB1_ST	Q9UN36	NDRG2	P23443	RPS6KB1	T348	S353G	353	Missense	distal	5	no	34.565	33.429	EPSD	COSMIC	24.279	Down-regulation
AGC_RSK_RSKp70_RPS6KB1_ST	Q9UN36	NDRG2	P23443	RPS6KB1	T348	R345L	345	Missense	distal	-3	no	34.565	24.898	EPSD	COSMIC	24.279	Down-regulation
AGC_RSK_RSKp70_RPS6KB1_ST	Q9UN36	NDRG2	P23443	RPS6KB1	S350	S355F	355	Missense	distal	5	no	38.747	33.385	PhosphoSitePlus;EPSD	COSMIC	24.279	Down-regulation
AGC_RSK_RSKp70_RPS6KB1_ST	Q9UN36	NDRG2	P23443	RPS6KB1	S350	L349M	349	Missense	proximal	-1	no	38.747	38.753	PhosphoSitePlus;EPSD	COSMIC	24.279	Up-regulation
AGC_RSK_RSKp70_RPS6KB1_ST	Q9UN36	NDRG2	P23443	RPS6KB1	S350	S353G	353	Missense	distal	3	no	38.747	34.753	PhosphoSitePlus;EPSD	COSMIC	24.279	Down-regulation
AGC_RSK_RSKp70_RPS6KB1_ST	Q9UN36	NDRG2	P23443	RPS6KB1	S350	R345L	345	Missense	distal	-5	no	38.747	30.123	PhosphoSitePlus;EPSD	COSMIC	24.279	Down-regulation
AGC_RSK_RSKp70_RPS6KB1_ST	Q9UN36	NDRG2	P23443	RPS6KB1	S355	S359F	359	Missense	distal	4	no	27.881	25.720	EPSD	COSMIC	24.279	Down-regulation
AGC_RSK_RSKp70_RPS6KB1_ST	Q9UN36	NDRG2	P23443	RPS6KB1	S355	S355F	355	Missense	central	0	yes	27.881	0.000	EPSD	COSMIC	24.279	Loss
AGC_RSK_RSKp70_RPS6KB1_ST	Q9UN36	NDRG2	P23443	RPS6KB1	S355	S360L	360	Missense	distal	5	no	27.881	27.171	EPSD	COSMIC	24.279	Down-regulation
AGC_RSK_RSKp70_RPS6KB1_ST	Q9UN36	NDRG2	P23443	RPS6KB1	S355	L349M	349	Missense	distal	-6	no	27.881	27.869	EPSD	COSMIC	24.279	Down-regulation
AGC_RSK_RSKp70_RPS6KB1_ST	Q9UN36	NDRG2	P23443	RPS6KB1	S355	S353G	353	Missense	proximal	-2	no	27.881	27.661	EPSD	COSMIC	24.279	Down-regulation
AGC_RSK_RSKp70_RPS6KB1_ST	Q9UN36	NDRG2	P23443	RPS6KB1	S359	S359F	359	Missense	central	0	yes	29.144	0.000	EPSD	COSMIC	24.279	Loss
AGC_RSK_RSKp70_RPS6KB1_ST	Q9UN36	NDRG2	P23443	RPS6KB1	S359	S355F	355	Missense	distal	-4	no	29.144	26.517	EPSD	COSMIC	24.279	Down-regulation
AGC_RSK_RSKp70_RPS6KB1_ST	Q9UN36	NDRG2	P23443	RPS6KB1	S359	S360L	360	Missense	proximal	1	no	29.144	30.248	EPSD	COSMIC	24.279	Up-regulation
AGC_RSK_RSKp70_RPS6KB1_ST	Q9UN36	NDRG2	P23443	RPS6KB1	S359	P363S	363	Missense	distal	4	no	29.144	30.078	EPSD	COSMIC	24.279	Up-regulation
AGC_RSK_RSKp70_RPS6KB1_ST	Q9UN36	NDRG2	P23443	RPS6KB1	S359	S353G	353	Missense	distal	-6	no	29.144	29.180	EPSD	COSMIC	24.279	Up-regulation
AGC_RSK_RSKp70_RPS6KB1_ST	Q9UN36	NDRG2	P23443	RPS6KB1	S359	P363L	363	Missense	distal	4	no	29.144	29.630	EPSD	COSMIC	24.279	Up-regulation
AGC_RSK_RSKp70_RPS6KB1_ST	P62753	RPS6	P23443	RPS6KB1	S6	P8L	8	Missense	proximal	2	no	24.103	25.281	EPSD	COSMIC	24.279	Gain
AGC_RSK_RSKp70_RPS6KB1_ST	P62753	RPS6	P23443	RPS6KB1	T34	M32L	32	Missense	proximal	-2	no	35.593	35.053	EPSD	COSMIC	24.279	Down-regulation
AGC_RSK_RSKp70_RPS6KB1_ST	P62753	RPS6	P23443	RPS6KB1	T34	F27L	27	Missense	distal	-7	no	35.593	35.379	EPSD	COSMIC	24.279	Down-regulation
AGC_RSK_RSKp70_RPS6KB1_ST	P49841	GSK3B	P23443	RPS6KB1	T7	S9F	9	Missense	proximal	2	no	27.025	21.827	EPSD	COSMIC	24.279	Loss
AGC_RSK_RSKp70_RPS6KB1_ST	P49841	GSK3B	P23443	RPS6KB1	T7	S2P	2	Missense	distal	-5	no	27.025	24.086	EPSD	COSMIC	24.279	Loss
AGC_RSK_RSKp70_RPS6KB1_ST	P49841	GSK3B	P23443	RPS6KB1	S9	S9F	9	Missense	central	0	yes	43.554	0.000	PhosphoSitePlus	COSMIC	24.279	Loss
AGC_RSK_RSKp70_RPS6KB1_ST	P49841	GSK3B	P23443	RPS6KB1	S9	P16A	16	Missense	distal	7	no	43.554	43.714	PhosphoSitePlus	COSMIC	24.279	Up-regulation
AGC_RSK_RSKp70_RPS6KB1_ST	P49841	GSK3B	P23443	RPS6KB1	S9	S2P	2	Missense	distal	-7	no	43.554	43.765	PhosphoSitePlus	COSMIC	24.279	Up-regulation
AGC_RSK_RSKp70_RPS6KB1_ST	P49841	GSK3B	P23443	RPS6KB1	S13	S9F	9	Missense	distal	-4	no	27.467	24.840	EPSD	COSMIC	24.279	Down-regulation
AGC_RSK_RSKp70_RPS6KB1_ST	P49841	GSK3B	P23443	RPS6KB1	S13	P16A	16	Missense	distal	3	no	27.467	27.558	EPSD	COSMIC	24.279	Up-regulation
AGC_RSK_RSKp70_RPS6KB1_ST	P49841	GSK3B	P23443	RPS6KB1	S29	D31Y	31	Missense	proximal	2	no	25.021	24.249	EPSD	COSMIC	24.279	Loss
AGC_RSK_RSKp70_RPS6KB1_ST	P49841	GSK3B	P23443	RPS6KB1	S29	S25C	25	Missense	distal	-4	no	25.021	22.570	EPSD	COSMIC	24.279	Loss
AGC_RSK_RSKp70_RPS6KB1_ST	P49841	GSK3B	P23443	RPS6KB1	S29	D33N	33	Missense	distal	4	no	25.021	25.035	EPSD	COSMIC	24.279	Up-regulation
AGC_RSK_RSKp70_RPS6KB1_ST	P49841	GSK3B	P23443	RPS6KB1	S29	S35R	35	Missense	distal	6	no	25.021	24.444	EPSD	COSMIC	24.279	Down-regulation
AGC_RSK_RSKp70_RPS6KB1_ST	P49841	GSK3B	P23443	RPS6KB1	S29	D33G	33	Missense	distal	4	no	25.021	24.512	EPSD	COSMIC;GDSC;CCLE	24.279	Down-regulation
AGC_RSK_RSKp70_RPS6KB1_ST	P49841	GSK3B	P23443	RPS6KB1	S29	D33H	33	Missense	distal	4	no	25.021	24.966	EPSD	COSMIC	24.279	Down-regulation
AGC_RSK_RSKp70_RPS6KB1_ST	P49841	GSK3B	P23443	RPS6KB1	S29	A22T	22	Missense	distal	-7	no	25.021	24.928	EPSD	COSMIC	24.279	Down-regulation
AGC_RSK_RSKp70_RPS6KB1_ST	P49841	GSK3B	P23443	RPS6KB1	S35	D31Y	31	Missense	distal	-4	no	26.546	26.686	EPSD	COSMIC	24.279	Up-regulation
AGC_RSK_RSKp70_RPS6KB1_ST	P49841	GSK3B	P23443	RPS6KB1	S35	D33N	33	Missense	proximal	-2	no	26.546	26.531	EPSD	COSMIC	24.279	Down-regulation
AGC_RSK_RSKp70_RPS6KB1_ST	P49841	GSK3B	P23443	RPS6KB1	S35	S35R	35	Missense	central	0	yes	26.546	0.000	EPSD	COSMIC	24.279	Loss
AGC_RSK_RSKp70_RPS6KB1_ST	P49841	GSK3B	P23443	RPS6KB1	S35	V41G	41	Missense	distal	6	no	26.546	27.935	EPSD	COSMIC	24.279	Up-regulation
AGC_RSK_RSKp70_RPS6KB1_ST	P49841	GSK3B	P23443	RPS6KB1	S35	V37G	37	Missense	proximal	2	no	26.546	28.435	EPSD	COSMIC	24.279	Up-regulation
AGC_RSK_RSKp70_RPS6KB1_ST	P49841	GSK3B	P23443	RPS6KB1	S35	D33G	33	Missense	proximal	-2	no	26.546	24.655	EPSD	COSMIC;GDSC;CCLE	24.279	Down-regulation
AGC_RSK_RSKp70_RPS6KB1_ST	P49841	GSK3B	P23443	RPS6KB1	S35	D33H	33	Missense	proximal	-2	no	26.546	25.450	EPSD	COSMIC	24.279	Down-regulation
AGC_RSK_RSKp70_RPS6KB1_ST	P49841	GSK3B	P23443	RPS6KB1	S66	G63A	63	Missense	distal	-3	no	29.544	27.447	EPSD	COSMIC	24.279	Down-regulation
AGC_RSK_RSKp70_RPS6KB1_ST	P49841	GSK3B	P23443	RPS6KB1	S66	Y71H	71	Missense	distal	5	no	29.544	31.912	EPSD	COSMIC	24.279	Up-regulation
AGC_RSK_RSKp70_RPS6KB1_ST	P49841	GSK3B	P23443	RPS6KB1	S66	G65E	65	Missense	proximal	-1	no	29.544	29.465	EPSD	COSMIC;GDSC;CCLE	24.279	Down-regulation
AGC_RSK_RSKp70_RPS6KB1_ST	P49841	GSK3B	P23443	RPS6KB1	S66	A73T	73	Missense	distal	7	no	29.544	29.192	EPSD	COSMIC	24.279	Down-regulation
AGC_RSK_RSKp70_RPS6KB1_ST	P49841	GSK3B	P23443	RPS6KB1	S66	A73G	73	Missense	distal	7	no	29.544	29.479	EPSD	COSMIC	24.279	Down-regulation
AGC_RSK_RSKp70_RPS6KB1_ST	P49841	GSK3B	P23443	RPS6KB1	T408	R405S	405	Missense	distal	-3	no	24.977	15.494	EPSD	COSMIC	24.279	Loss
AGC_RSK_RSKp70_RPS6KB1_ST	P49841	GSK3B	P23443	RPS6KB1	T408	T402I	402	Missense	distal	-6	no	24.977	25.019	EPSD	COSMIC	24.279	Up-regulation
AGC_RSK_RSKp70_RPS6KB1_ST	P49841	GSK3B	P23443	RPS6KB1	T408	R405H	405	Missense	distal	-3	no	24.977	21.489	EPSD	COSMIC;CCLE	24.279	Loss
AGC_RSK_RSKp70_RPS6KB1_ST	Q53EL6	PDCD4	P23443	RPS6KB1	S76	G81E	81	Missense	distal	5	no	35.747	35.493	EPSD	COSMIC	24.279	Down-regulation
AGC_RSK_RSKp70_RPS6KB1_ST	Q53EL6	PDCD4	P23443	RPS6KB1	S78	G81E	81	Missense	distal	3	no	20.929	25.158	EPSD	COSMIC	24.279	Gain
AGC_RSK_RSKp70_RPS6KB1_ST	Q53EL6	PDCD4	P23443	RPS6KB1	T234	G228W	228	Missense	distal	-6	no	25.863	25.897	EPSD	COSMIC	24.279	Up-regulation
AGC_RSK_RSKp70_RPS6KB1_ST	Q53EL6	PDCD4	P23443	RPS6KB1	T234	D235Y	235	Missense	proximal	1	no	25.863	26.699	EPSD	COSMIC	24.279	Up-regulation
AGC_RSK_RSKp70_RPS6KB1_ST	Q53EL6	PDCD4	P23443	RPS6KB1	S313	G307V	307	Missense	distal	-6	no	25.958	25.998	EPSD	COSMIC	24.279	Up-regulation
AGC_RSK_RSKp70_RPS6KB1_ST	Q53EL6	PDCD4	P23443	RPS6KB1	S345	I344T	344	Missense	proximal	-1	no	30.675	30.648	EPSD	COSMIC;GDSC;CCLE	24.279	Down-regulation
AGC_RSK_RSKp70_RPS6KB1_ST	Q53EL6	PDCD4	P23443	RPS6KB1	S345	S345F	345	Missense	central	0	yes	30.675	0.000	EPSD	COSMIC	24.279	Loss
AGC_RSK_RSKp70_RPS6KB1_ST	Q53EL6	PDCD4	P23443	RPS6KB1	S345	H349N	349	Missense	distal	4	no	30.675	30.744	EPSD	COSMIC	24.279	Up-regulation
AGC_RSK_RSKp70_RPS6KB1_ST	Q53EL6	PDCD4	P23443	RPS6KB1	S457	G451D	451	Missense	distal	-6	no	26.949	26.977	EPSD;PhosphoSitePlus	COSMIC	24.279	Up-regulation
AGC_RSK_RSKp70_RPS6KB1_ST	Q9H3D4	TP63	P23443	RPS6KB1	S43	S41F	41	Missense	proximal	-2	no	22.484	24.351	EPSD	COSMIC	24.279	Gain
AGC_RSK_RSKp70_RPS6KB1_ST	Q9H3D4	TP63	P23443	RPS6KB1	S51	E48K	48	Missense	distal	-3	no	22.357	25.084	EPSD	COSMIC	24.279	Gain
AGC_RSK_RSKp70_RPS6KB1_ST	Q9H3D4	TP63	P23443	RPS6KB1	S365	Q362H	362	Missense	distal	-3	no	20.951	36.518	EPSD	COSMIC	24.279	Gain
AGC_RSK_RSKp70_RPS6KB1_ST	Q9H3D4	TP63	P23443	RPS6KB1	S551	A554E	554	Missense	distal	3	no	22.802	25.485	EPSD	COSMIC	24.279	Gain
AGC_RSK_RSKp70_RPS6KB1_ST	Q9H3D4	TP63	P23443	RPS6KB1	S560	T566M	566	Missense	distal	6	no	37.439	36.422	PhosphoSitePlus	COSMIC	24.279	Down-regulation
AGC_RSK_RSKp70_RPS6KB1_ST	Q9H3D4	TP63	P23443	RPS6KB1	S560	S560A	560	Missense	central	0	yes	37.439	0.000	PhosphoSitePlus	COSMIC;GDSC;CCLE	24.279	Loss
AGC_RSK_RSKp70_RPS6KB1_ST	Q9H3D4	TP63	P23443	RPS6KB1	S560	S560L	560	Missense	central	0	yes	37.439	0.000	PhosphoSitePlus	COSMIC	24.279	Loss
AGC_RSK_RSKp70_RPS6KB1_ST	Q9H3D4	TP63	P23443	RPS6KB1	S560	A554E	554	Missense	distal	-6	no	37.439	37.421	PhosphoSitePlus	COSMIC	24.279	Down-regulation
AGC_RSK_RSKp70_RPS6KB1_ST	Q9H3D4	TP63	P23443	RPS6KB1	S560	R555S	555	Missense	distal	-5	no	37.439	31.899	PhosphoSitePlus	COSMIC	24.279	Down-regulation
AGC_RSK_RSKp70_RPS6KB1_ST	Q9H3D4	TP63	P23443	RPS6KB1	S622	V628E	628	Missense	distal	6	no	24.035	24.559	EPSD	COSMIC	24.279	Gain
AGC_RSK_RSKp70_RPS6KB1_ST	Q9H3D4	TP63	P23443	RPS6KB1	S622	V628M	628	Missense	distal	6	no	24.035	24.310	EPSD	COSMIC	24.279	Gain
AGC_RSK_RSKp70_RPS6KB1_ST	P10636	MAPT	P23443	RPS6KB1	T17	R23K	23	Missense	distal	6	no	26.536	26.383	EPSD	COSMIC	24.279	Down-regulation
AGC_RSK_RSKp70_RPS6KB1_ST	P10636	MAPT	P23443	RPS6KB1	S56	E62K	62	Missense	distal	6	no	25.475	25.445	EPSD	COSMIC	24.279	Down-regulation
AGC_RSK_RSKp70_RPS6KB1_ST	P10636	MAPT	P23443	RPS6KB1	T69	E62K	62	Missense	distal	-7	no	25.024	25.125	EPSD	COSMIC	24.279	Up-regulation
AGC_RSK_RSKp70_RPS6KB1_ST	P10636	MAPT	P23443	RPS6KB1	S171	P175S	175	Missense	distal	4	no	32.927	33.861	EPSD	COSMIC	24.279	Up-regulation
AGC_RSK_RSKp70_RPS6KB1_ST	P10636	MAPT	P23443	RPS6KB1	S171	A166V	166	Missense	distal	-5	no	32.927	31.885	EPSD	COSMIC;CCLE	24.279	Down-regulation
AGC_RSK_RSKp70_RPS6KB1_ST	P10636	MAPT	P23443	RPS6KB1	S171	E176G	176	Missense	distal	5	no	32.927	33.181	EPSD	COSMIC	24.279	Up-regulation
AGC_RSK_RSKp70_RPS6KB1_ST	P10636	MAPT	P23443	RPS6KB1	S171	D177G	177	Missense	distal	6	no	32.927	34.410	EPSD	COSMIC	24.279	Up-regulation
AGC_RSK_RSKp70_RPS6KB1_ST	P10636	MAPT	P23443	RPS6KB1	S171	E165K	165	Missense	distal	-6	no	32.927	32.919	EPSD	COSMIC	24.279	Down-regulation
AGC_RSK_RSKp70_RPS6KB1_ST	P10636	MAPT	P23443	RPS6KB1	S171	G172V	172	Missense	proximal	1	no	32.927	32.498	EPSD	COSMIC	24.279	Down-regulation
AGC_RSK_RSKp70_RPS6KB1_ST	P10636	MAPT	P23443	RPS6KB1	S214	E210Q	210	Missense	distal	-4	no	27.785	26.210	PhosphoSitePlus;EPSD	COSMIC	24.279	Down-regulation
AGC_RSK_RSKp70_RPS6KB1_ST	P10636	MAPT	P23443	RPS6KB1	S214	G207E	207	Missense	distal	-7	no	27.785	27.560	PhosphoSitePlus;EPSD	COSMIC	24.279	Down-regulation
AGC_RSK_RSKp70_RPS6KB1_ST	P10636	MAPT	P23443	RPS6KB1	S227	Q230R	230	Missense	distal	3	no	23.592	24.919	EPSD	COSMIC	24.279	Gain
AGC_RSK_RSKp70_RPS6KB1_ST	P10636	MAPT	P23443	RPS6KB1	S227	P233S	233	Missense	distal	6	no	23.592	24.567	EPSD	COSMIC	24.279	Gain
AGC_RSK_RSKp70_RPS6KB1_ST	P10636	MAPT	P23443	RPS6KB1	S232	A237T	237	Missense	distal	5	no	23.673	24.516	EPSD	COSMIC	24.279	Gain
AGC_RSK_RSKp70_RPS6KB1_ST	P10636	MAPT	P23443	RPS6KB1	S238	A240S	240	Missense	proximal	2	no	22.027	24.889	EPSD	COSMIC	24.279	Gain
AGC_RSK_RSKp70_RPS6KB1_ST	P10636	MAPT	P23443	RPS6KB1	S238	P233S	233	Missense	distal	-5	no	22.027	24.965	EPSD	COSMIC	24.279	Gain
AGC_RSK_RSKp70_RPS6KB1_ST	P10636	MAPT	P23443	RPS6KB1	S341	A337T	337	Missense	distal	-4	no	38.788	39.019	EPSD	COSMIC	24.279	Up-regulation
AGC_RSK_RSKp70_RPS6KB1_ST	P10636	MAPT	P23443	RPS6KB1	S341	G343R	343	Missense	proximal	2	no	38.788	38.494	EPSD	COSMIC	24.279	Down-regulation
AGC_RSK_RSKp70_RPS6KB1_ST	P10636	MAPT	P23443	RPS6KB1	S341	D345G	345	Missense	distal	4	no	38.788	38.280	EPSD	COSMIC	24.279	Down-regulation
AGC_RSK_RSKp70_RPS6KB1_ST	P10636	MAPT	P23443	RPS6KB1	S341	K347N	347	Missense	distal	6	no	38.788	38.061	EPSD	COSMIC	24.279	Down-regulation
AGC_RSK_RSKp70_RPS6KB1_ST	P10636	MAPT	P23443	RPS6KB1	S369	V368I	368	Missense	proximal	-1	no	30.152	30.141	EPSD	COSMIC	24.279	Down-regulation
AGC_RSK_RSKp70_RPS6KB1_ST	P10636	MAPT	P23443	RPS6KB1	S369	R370W	370	Missense	proximal	1	no	30.152	30.627	EPSD	COSMIC	24.279	Up-regulation
AGC_RSK_RSKp70_RPS6KB1_ST	P10636	MAPT	P23443	RPS6KB1	T403	S396F	396	Missense	distal	-7	no	23.934	24.295	EPSD	COSMIC	24.279	Gain
AGC_RSK_RSKp70_RPS6KB1_ST	P10636	MAPT	P23443	RPS6KB1	S419	P412S	412	Missense	distal	-7	no	25.020	24.809	EPSD	COSMIC	24.279	Down-regulation
AGC_RSK_RSKp70_RPS6KB1_ST	P10636	MAPT	P23443	RPS6KB1	S447	S443Y	443	Missense	distal	-4	no	29.223	28.199	EPSD	COSMIC	24.279	Down-regulation
AGC_RSK_RSKp70_RPS6KB1_ST	P10636	MAPT	P23443	RPS6KB1	S447	S447P	447	Missense	central	0	yes	29.223	0.000	EPSD	COSMIC	24.279	Loss
AGC_RSK_RSKp70_RPS6KB1_ST	P10636	MAPT	P23443	RPS6KB1	S447	R448Q	448	Missense	proximal	1	no	29.223	28.977	EPSD	COSMIC	24.279	Down-regulation
AGC_RSK_RSKp70_RPS6KB1_ST	P10636	MAPT	P23443	RPS6KB1	S451	S447P	447	Missense	distal	-4	no	31.589	29.924	EPSD	COSMIC	24.279	Down-regulation
AGC_RSK_RSKp70_RPS6KB1_ST	P10636	MAPT	P23443	RPS6KB1	S451	R448Q	448	Missense	distal	-3	no	31.589	12.534	EPSD	COSMIC	24.279	Loss
AGC_RSK_RSKp70_RPS6KB1_ST	P10636	MAPT	P23443	RPS6KB1	S512	P506S	506	Missense	distal	-6	no	24.496	24.445	EPSD	COSMIC	24.279	Down-regulation
AGC_RSK_RSKp70_RPS6KB1_ST	P10636	MAPT	P23443	RPS6KB1	S512	G518V	518	Missense	distal	6	no	24.496	23.106	EPSD	COSMIC	24.279	Loss
AGC_RSK_RSKp70_RPS6KB1_ST	P10636	MAPT	P23443	RPS6KB1	S512	R511C	511	Missense	proximal	-1	no	24.496	24.569	EPSD	COSMIC;CCLE	24.279	Up-regulation
AGC_RSK_RSKp70_RPS6KB1_ST	P10636	MAPT	P23443	RPS6KB1	S512	G509V	509	Missense	distal	-3	no	24.496	17.567	EPSD	COSMIC	24.279	Loss
AGC_RSK_RSKp70_RPS6KB1_ST	P10636	MAPT	P23443	RPS6KB1	S512	P506L	506	Missense	distal	-6	no	24.496	24.489	EPSD	COSMIC	24.279	Down-regulation
AGC_RSK_RSKp70_RPS6KB1_ST	P10636	MAPT	P23443	RPS6KB1	S516	G521V	521	Missense	distal	5	no	24.626	23.371	EPSD	COSMIC	24.279	Loss
AGC_RSK_RSKp70_RPS6KB1_ST	P10636	MAPT	P23443	RPS6KB1	S516	G518V	518	Missense	proximal	2	no	24.626	22.737	EPSD	COSMIC	24.279	Loss
AGC_RSK_RSKp70_RPS6KB1_ST	P10636	MAPT	P23443	RPS6KB1	S516	R511C	511	Missense	distal	-5	no	24.626	15.393	EPSD	COSMIC;CCLE	24.279	Loss
AGC_RSK_RSKp70_RPS6KB1_ST	P10636	MAPT	P23443	RPS6KB1	S516	G509V	509	Missense	distal	-7	no	24.626	24.786	EPSD	COSMIC	24.279	Up-regulation
AGC_RSK_RSKp70_RPS6KB1_ST	P10636	MAPT	P23443	RPS6KB1	S519	G521V	521	Missense	proximal	2	no	30.096	28.207	EPSD	COSMIC	24.279	Down-regulation
AGC_RSK_RSKp70_RPS6KB1_ST	P10636	MAPT	P23443	RPS6KB1	S519	R526H	526	Missense	distal	7	no	30.096	29.983	EPSD	COSMIC	24.279	Down-regulation
AGC_RSK_RSKp70_RPS6KB1_ST	P10636	MAPT	P23443	RPS6KB1	S519	G518V	518	Missense	proximal	-1	no	30.096	30.076	EPSD	COSMIC	24.279	Down-regulation
AGC_RSK_RSKp70_RPS6KB1_ST	P10636	MAPT	P23443	RPS6KB1	T522	G521V	521	Missense	proximal	-1	no	25.064	25.043	EPSD	COSMIC	24.279	Down-regulation
AGC_RSK_RSKp70_RPS6KB1_ST	P10636	MAPT	P23443	RPS6KB1	T522	R526H	526	Missense	distal	4	no	25.064	25.126	EPSD	COSMIC	24.279	Up-regulation
AGC_RSK_RSKp70_RPS6KB1_ST	P10636	MAPT	P23443	RPS6KB1	T522	G518V	518	Missense	distal	-4	no	25.064	26.000	EPSD	COSMIC	24.279	Up-regulation
AGC_RSK_RSKp70_RPS6KB1_ST	P10636	MAPT	P23443	RPS6KB1	T522	R528S	528	Missense	distal	6	no	25.064	25.641	EPSD	COSMIC	24.279	Up-regulation
AGC_RSK_RSKp70_RPS6KB1_ST	P10636	MAPT	P23443	RPS6KB1	S525	G521V	521	Missense	distal	-4	no	28.457	29.393	EPSD	COSMIC	24.279	Up-regulation
AGC_RSK_RSKp70_RPS6KB1_ST	P10636	MAPT	P23443	RPS6KB1	S525	R526H	526	Missense	proximal	1	no	28.457	28.050	EPSD	COSMIC	24.279	Down-regulation
AGC_RSK_RSKp70_RPS6KB1_ST	P10636	MAPT	P23443	RPS6KB1	S525	G518V	518	Missense	distal	-7	no	28.457	28.618	EPSD	COSMIC	24.279	Up-regulation
AGC_RSK_RSKp70_RPS6KB1_ST	P10636	MAPT	P23443	RPS6KB1	S525	R528S	528	Missense	distal	3	no	28.457	30.024	EPSD	COSMIC	24.279	Up-regulation
AGC_RSK_RSKp70_RPS6KB1_ST	P10636	MAPT	P23443	RPS6KB1	S525	P530S	530	Missense	distal	5	no	28.457	30.391	EPSD	COSMIC	24.279	Up-regulation
AGC_RSK_RSKp70_RPS6KB1_ST	P10636	MAPT	P23443	RPS6KB1	T529	R526H	526	Missense	distal	-3	no	35.856	32.368	EPSD	COSMIC	24.279	Down-regulation
AGC_RSK_RSKp70_RPS6KB1_ST	P10636	MAPT	P23443	RPS6KB1	T529	R528S	528	Missense	proximal	-1	no	35.856	35.827	EPSD	COSMIC	24.279	Down-regulation
AGC_RSK_RSKp70_RPS6KB1_ST	P10636	MAPT	P23443	RPS6KB1	T529	P530S	530	Missense	proximal	1	no	35.856	34.839	EPSD	COSMIC	24.279	Down-regulation
AGC_RSK_RSKp70_RPS6KB1_ST	P10636	MAPT	P23443	RPS6KB1	T529	P536H	536	Missense	distal	7	no	35.856	35.684	EPSD	COSMIC	24.279	Down-regulation
AGC_RSK_RSKp70_RPS6KB1_ST	P10636	MAPT	P23443	RPS6KB1	T529	P535Q	535	Missense	distal	6	no	35.856	36.069	EPSD	COSMIC	24.279	Up-regulation
AGC_RSK_RSKp70_RPS6KB1_ST	P10636	MAPT	P23443	RPS6KB1	S531	R526H	526	Missense	distal	-5	no	44.735	41.880	EPSD	COSMIC	24.279	Down-regulation
AGC_RSK_RSKp70_RPS6KB1_ST	P10636	MAPT	P23443	RPS6KB1	S531	R528S	528	Missense	distal	-3	no	44.735	35.251	EPSD	COSMIC	24.279	Down-regulation
AGC_RSK_RSKp70_RPS6KB1_ST	P10636	MAPT	P23443	RPS6KB1	S531	P530S	530	Missense	proximal	-1	no	44.735	44.638	EPSD	COSMIC	24.279	Down-regulation
AGC_RSK_RSKp70_RPS6KB1_ST	P10636	MAPT	P23443	RPS6KB1	S531	P536H	536	Missense	distal	5	no	44.735	45.073	EPSD	COSMIC	24.279	Up-regulation
AGC_RSK_RSKp70_RPS6KB1_ST	P10636	MAPT	P23443	RPS6KB1	S531	P535Q	535	Missense	distal	4	no	44.735	44.552	EPSD	COSMIC	24.279	Down-regulation
AGC_RSK_RSKp70_RPS6KB1_ST	P10636	MAPT	P23443	RPS6KB1	S552	P550S	550	Missense	proximal	-2	no	28.992	27.085	EPSD	COSMIC	24.279	Down-regulation
AGC_RSK_RSKp70_RPS6KB1_ST	P10636	MAPT	P23443	RPS6KB1	S552	R559C	559	Missense	distal	7	no	28.992	27.990	EPSD	COSMIC	24.279	Down-regulation
AGC_RSK_RSKp70_RPS6KB1_ST	P10636	MAPT	P23443	RPS6KB1	S552	P553R	553	Missense	proximal	1	no	28.992	28.764	EPSD	COSMIC	24.279	Down-regulation
AGC_RSK_RSKp70_RPS6KB1_ST	P10636	MAPT	P23443	RPS6KB1	S552	P553L	553	Missense	proximal	1	no	28.992	29.078	EPSD	COSMIC	24.279	Up-regulation
AGC_RSK_RSKp70_RPS6KB1_ST	P10636	MAPT	P23443	RPS6KB1	S552	P549L	549	Missense	distal	-3	no	28.992	31.945	EPSD	COSMIC	24.279	Up-regulation
AGC_RSK_RSKp70_RPS6KB1_ST	P10636	MAPT	P23443	RPS6KB1	S552	S555F	555	Missense	distal	3	no	28.992	25.602	EPSD	COSMIC	24.279	Down-regulation
AGC_RSK_RSKp70_RPS6KB1_ST	P10636	MAPT	P23443	RPS6KB1	S552	P553Q	553	Missense	proximal	1	no	28.992	28.518	EPSD	COSMIC	24.279	Down-regulation
AGC_RSK_RSKp70_RPS6KB1_ST	P10636	MAPT	P23443	RPS6KB1	S554	P550S	550	Missense	distal	-4	no	25.150	26.816	EPSD	COSMIC	24.279	Up-regulation
AGC_RSK_RSKp70_RPS6KB1_ST	P10636	MAPT	P23443	RPS6KB1	S554	R559C	559	Missense	distal	5	no	25.150	23.650	EPSD	COSMIC	24.279	Loss
AGC_RSK_RSKp70_RPS6KB1_ST	P10636	MAPT	P23443	RPS6KB1	S554	P553R	553	Missense	proximal	-1	no	25.150	25.083	EPSD	COSMIC	24.279	Down-regulation
AGC_RSK_RSKp70_RPS6KB1_ST	P10636	MAPT	P23443	RPS6KB1	S554	P553L	553	Missense	proximal	-1	no	25.150	25.103	EPSD	COSMIC	24.279	Down-regulation
AGC_RSK_RSKp70_RPS6KB1_ST	P10636	MAPT	P23443	RPS6KB1	S554	P549L	549	Missense	distal	-5	no	25.150	25.004	EPSD	COSMIC	24.279	Down-regulation
AGC_RSK_RSKp70_RPS6KB1_ST	P10636	MAPT	P23443	RPS6KB1	S554	S555F	555	Missense	proximal	1	no	25.150	26.699	EPSD	COSMIC	24.279	Up-regulation
AGC_RSK_RSKp70_RPS6KB1_ST	P10636	MAPT	P23443	RPS6KB1	S554	P553Q	553	Missense	proximal	-1	no	25.150	25.111	EPSD	COSMIC	24.279	Down-regulation
AGC_RSK_RSKp70_RPS6KB1_ST	P10636	MAPT	P23443	RPS6KB1	S555	P550S	550	Missense	distal	-5	no	25.056	27.995	EPSD	COSMIC	24.279	Up-regulation
AGC_RSK_RSKp70_RPS6KB1_ST	P10636	MAPT	P23443	RPS6KB1	S555	R559C	559	Missense	distal	4	no	25.056	24.408	EPSD	COSMIC	24.279	Down-regulation
AGC_RSK_RSKp70_RPS6KB1_ST	P10636	MAPT	P23443	RPS6KB1	S555	P553R	553	Missense	proximal	-2	no	25.056	23.795	EPSD	COSMIC	24.279	Loss
AGC_RSK_RSKp70_RPS6KB1_ST	P10636	MAPT	P23443	RPS6KB1	S555	P553L	553	Missense	proximal	-2	no	25.056	23.292	EPSD	COSMIC	24.279	Loss
AGC_RSK_RSKp70_RPS6KB1_ST	P10636	MAPT	P23443	RPS6KB1	S555	P549L	549	Missense	distal	-6	no	25.056	25.049	EPSD	COSMIC	24.279	Down-regulation
AGC_RSK_RSKp70_RPS6KB1_ST	P10636	MAPT	P23443	RPS6KB1	S555	S555F	555	Missense	central	0	yes	25.056	0.000	EPSD	COSMIC	24.279	Loss
AGC_RSK_RSKp70_RPS6KB1_ST	P10636	MAPT	P23443	RPS6KB1	S555	P553Q	553	Missense	proximal	-2	no	25.056	24.597	EPSD	COSMIC	24.279	Down-regulation
AGC_RSK_RSKp70_RPS6KB1_ST	P10636	MAPT	P23443	RPS6KB1	S558	P553R	553	Missense	distal	-5	no	19.743	28.222	EPSD	COSMIC	24.279	Gain
AGC_RSK_RSKp70_RPS6KB1_ST	P10636	MAPT	P23443	RPS6KB1	S579	T580N	580	Missense	proximal	1	no	35.263	34.059	EPSD	COSMIC	24.279	Down-regulation
AGC_RSK_RSKp70_RPS6KB1_ST	P10636	MAPT	P23443	RPS6KB1	S579	G578S	578	Missense	proximal	-1	no	35.263	35.178	EPSD	COSMIC	24.279	Down-regulation
AGC_RSK_RSKp70_RPS6KB1_ST	P10636	MAPT	P23443	RPS6KB1	S641	H647Y	647	Missense	distal	6	no	26.786	25.489	EPSD	COSMIC	24.279	Down-regulation
AGC_RSK_RSKp70_RPS6KB1_ST	P10636	MAPT	P23443	RPS6KB1	S669	S669L	669	Missense	central	0	yes	31.266	0.000	EPSD	COSMIC	24.279	Loss
AGC_RSK_RSKp70_RPS6KB1_ST	P10636	MAPT	P23443	RPS6KB1	S669	R666K	666	Missense	distal	-3	no	31.266	23.647	EPSD	COSMIC	24.279	Loss
AGC_RSK_RSKp70_RPS6KB1_ST	P10636	MAPT	P23443	RPS6KB1	S669	D662G	662	Missense	distal	-7	no	31.266	31.226	EPSD	COSMIC	24.279	Down-regulation
AGC_RSK_RSKp70_RPS6KB1_ST	P10636	MAPT	P23443	RPS6KB1	S669	S673F	673	Missense	distal	4	no	31.266	29.105	EPSD	COSMIC	24.279	Down-regulation
AGC_RSK_RSKp70_RPS6KB1_ST	P10636	MAPT	P23443	RPS6KB1	S669	K670N	670	Missense	proximal	1	no	31.266	31.209	EPSD	COSMIC	24.279	Down-regulation
AGC_RSK_RSKp70_RPS6KB1_ST	P10636	MAPT	P23443	RPS6KB1	S669	K664N	664	Missense	distal	-5	no	31.266	30.409	EPSD	COSMIC	24.279	Down-regulation
AGC_RSK_RSKp70_RPS6KB1_ST	P10636	MAPT	P23443	RPS6KB1	S669	L674Q	674	Missense	distal	5	no	31.266	30.740	EPSD	COSMIC	24.279	Down-regulation
AGC_RSK_RSKp70_RPS6KB1_ST	P10636	MAPT	P23443	RPS6KB1	T694	R696H	696	Missense	proximal	2	no	25.236	25.756	EPSD	COSMIC	24.279	Up-regulation
AGC_RSK_RSKp70_RPS6KB1_ST	P10636	MAPT	P23443	RPS6KB1	T694	R696C	696	Missense	proximal	2	no	25.236	24.554	EPSD	COSMIC	24.279	Down-regulation
AGC_RSK_RSKp70_RPS6KB1_ST	P10636	MAPT	P23443	RPS6KB1	S713	V710M	710	Missense	distal	-3	no	19.518	28.773	EPSD	COSMIC	24.279	Gain
AGC_RSK_RSKp70_RPS6KB1_ST	P10636	MAPT	P23443	RPS6KB1	S713	V710A	710	Missense	distal	-3	no	19.518	24.351	EPSD	COSMIC	24.279	Gain
AGC_RSK_RSKp70_RPS6KB1_ST	P10636	MAPT	P23443	RPS6KB1	S721	V728M	728	Missense	distal	7	no	24.157	24.628	EPSD	COSMIC	24.279	Gain
AGC_RSK_RSKp70_RPS6KB1_ST	P10636	MAPT	P23443	RPS6KB1	S721	V728A	728	Missense	distal	7	no	24.157	24.761	EPSD	COSMIC	24.279	Gain
AGC_RSK_RSKp70_RPS6KB1_ST	P10636	MAPT	P23443	RPS6KB1	S729	G732S	732	Missense	distal	3	no	26.207	30.201	EPSD	COSMIC	24.279	Up-regulation
AGC_RSK_RSKp70_RPS6KB1_ST	P10636	MAPT	P23443	RPS6KB1	S729	D735N	735	Missense	distal	6	no	26.207	26.067	EPSD	COSMIC	24.279	Down-regulation
AGC_RSK_RSKp70_RPS6KB1_ST	P10636	MAPT	P23443	RPS6KB1	S729	G732C	732	Missense	distal	3	no	26.207	26.962	EPSD	COSMIC	24.279	Up-regulation
AGC_RSK_RSKp70_RPS6KB1_ST	P10636	MAPT	P23443	RPS6KB1	S729	R723W	723	Missense	distal	-6	no	26.207	26.270	EPSD	COSMIC	24.279	Up-regulation
AGC_RSK_RSKp70_RPS6KB1_ST	P10636	MAPT	P23443	RPS6KB1	S729	V728M	728	Missense	proximal	-1	no	26.207	26.196	EPSD	COSMIC	24.279	Down-regulation
AGC_RSK_RSKp70_RPS6KB1_ST	P10636	MAPT	P23443	RPS6KB1	S729	V728A	728	Missense	proximal	-1	no	26.207	26.246	EPSD	COSMIC	24.279	Up-regulation
AGC_RSK_RSKp70_RPS6KB1_ST	P10636	MAPT	P23443	RPS6KB1	S733	V728M	728	Missense	distal	-5	no	22.817	28.234	EPSD	COSMIC	24.279	Gain
AGC_RSK_RSKp70_RPS6KB1_ST	Q92519	TRIB2	P23443	RPS6KB1	S83	A78V	78	Missense	distal	-5	no	35.522	34.480	PhosphoSitePlus	COSMIC	24.279	Down-regulation
AGC_RSK_RSKp70_RPS6KB1_ST	Q8TB45	DEPTOR	P23443	RPS6KB1	T59	R54C	54	Missense	distal	-5	no	33.863	24.630	EPSD	COSMIC	24.279	Down-regulation
AGC_RSK_RSKp70_RPS6KB1_ST	Q8TB45	DEPTOR	P23443	RPS6KB1	S237	E233K	233	Missense	distal	-4	no	22.918	24.310	EPSD	COSMIC	24.279	Gain
AGC_RSK_RSKp70_RPS6KB1_ST	Q8TB45	DEPTOR	P23443	RPS6KB1	S238	P245A	245	Missense	distal	7	no	28.362	28.523	EPSD	COSMIC	24.279	Up-regulation
AGC_RSK_RSKp70_RPS6KB1_ST	Q8TB45	DEPTOR	P23443	RPS6KB1	S238	E233K	233	Missense	distal	-5	no	28.362	27.169	EPSD	COSMIC	24.279	Down-regulation
AGC_RSK_RSKp70_RPS6KB1_ST	Q8TB45	DEPTOR	P23443	RPS6KB1	S258	Q251R	251	Missense	distal	-7	no	25.719	25.649	EPSD	COSMIC	24.279	Down-regulation
AGC_RSK_RSKp70_RPS6KB1_ST	Q8TB45	DEPTOR	P23443	RPS6KB1	S258	S260I	260	Missense	proximal	2	no	25.719	22.479	EPSD	COSMIC	24.279	Loss
AGC_RSK_RSKp70_RPS6KB1_ST	Q8TB45	DEPTOR	P23443	RPS6KB1	S258	R256W	256	Missense	proximal	-2	no	25.719	26.636	EPSD	COSMIC	24.279	Up-regulation
AGC_RSK_RSKp70_RPS6KB1_ST	Q8TB45	DEPTOR	P23443	RPS6KB1	S263	S260I	260	Missense	distal	-3	no	28.945	23.516	EPSD	COSMIC	24.279	Loss
AGC_RSK_RSKp70_RPS6KB1_ST	Q8TB45	DEPTOR	P23443	RPS6KB1	S263	R256W	256	Missense	distal	-7	no	28.945	29.150	EPSD	COSMIC	24.279	Up-regulation
AGC_RSK_RSKp70_RPS6KB1_ST	Q8TB45	DEPTOR	P23443	RPS6KB1	S280	S282G	282	Missense	proximal	2	no	35.260	33.451	EPSD	COSMIC	24.279	Down-regulation
AGC_RSK_RSKp70_RPS6KB1_ST	Q8TB45	DEPTOR	P23443	RPS6KB1	S280	C284Y	284	Missense	distal	4	no	35.260	35.720	EPSD	COSMIC	24.279	Up-regulation
AGC_RSK_RSKp70_RPS6KB1_ST	Q8TB45	DEPTOR	P23443	RPS6KB1	S280	S286I	286	Missense	distal	6	no	35.260	34.136	EPSD	COSMIC	24.279	Down-regulation
AGC_RSK_RSKp70_RPS6KB1_ST	Q8TB45	DEPTOR	P23443	RPS6KB1	S283	S282G	282	Missense	proximal	-1	no	27.189	27.274	EPSD	COSMIC	24.279	Up-regulation
AGC_RSK_RSKp70_RPS6KB1_ST	Q8TB45	DEPTOR	P23443	RPS6KB1	S283	C284Y	284	Missense	proximal	1	no	27.189	26.816	EPSD	COSMIC	24.279	Down-regulation
AGC_RSK_RSKp70_RPS6KB1_ST	Q8TB45	DEPTOR	P23443	RPS6KB1	S283	S286I	286	Missense	distal	3	no	27.189	25.378	EPSD	COSMIC	24.279	Down-regulation
AGC_RSK_RSKp70_RPS6KB1_ST	Q8TB45	DEPTOR	P23443	RPS6KB1	S286	S282G	282	Missense	distal	-4	no	40.358	37.310	EPSD;PhosphoSitePlus	COSMIC	24.279	Down-regulation
AGC_RSK_RSKp70_RPS6KB1_ST	Q8TB45	DEPTOR	P23443	RPS6KB1	S286	C284Y	284	Missense	proximal	-2	no	40.358	39.060	EPSD;PhosphoSitePlus	COSMIC	24.279	Down-regulation
AGC_RSK_RSKp70_RPS6KB1_ST	Q8TB45	DEPTOR	P23443	RPS6KB1	S286	S286I	286	Missense	central	0	yes	40.358	0.000	EPSD;PhosphoSitePlus	COSMIC	24.279	Loss
AGC_RSK_RSKp70_RPS6KB1_ST	Q8TB45	DEPTOR	P23443	RPS6KB1	S287	S282G	282	Missense	distal	-5	no	36.376	34.671	PhosphoSitePlus;EPSD	COSMIC	24.279	Down-regulation
AGC_RSK_RSKp70_RPS6KB1_ST	Q8TB45	DEPTOR	P23443	RPS6KB1	S287	P294L	294	Missense	distal	7	no	36.376	36.333	PhosphoSitePlus;EPSD	COSMIC	24.279	Down-regulation
AGC_RSK_RSKp70_RPS6KB1_ST	Q8TB45	DEPTOR	P23443	RPS6KB1	S287	C284Y	284	Missense	distal	-3	no	36.376	29.086	PhosphoSitePlus;EPSD	COSMIC	24.279	Down-regulation
AGC_RSK_RSKp70_RPS6KB1_ST	Q8TB45	DEPTOR	P23443	RPS6KB1	S287	S286I	286	Missense	proximal	-1	no	36.376	36.430	PhosphoSitePlus;EPSD	COSMIC	24.279	Up-regulation
AGC_RSK_RSKp70_RPS6KB1_ST	Q8TB45	DEPTOR	P23443	RPS6KB1	S291	P294L	294	Missense	distal	3	no	38.136	38.976	EPSD;PhosphoSitePlus	COSMIC	24.279	Up-regulation
AGC_RSK_RSKp70_RPS6KB1_ST	Q8TB45	DEPTOR	P23443	RPS6KB1	S291	C284Y	284	Missense	distal	-7	no	38.136	38.241	EPSD;PhosphoSitePlus	COSMIC	24.279	Up-regulation
AGC_RSK_RSKp70_RPS6KB1_ST	Q8TB45	DEPTOR	P23443	RPS6KB1	S291	S298N	298	Missense	distal	7	no	38.136	37.357	EPSD;PhosphoSitePlus	COSMIC	24.279	Down-regulation
AGC_RSK_RSKp70_RPS6KB1_ST	Q8TB45	DEPTOR	P23443	RPS6KB1	S291	S286I	286	Missense	distal	-5	no	38.136	32.506	EPSD;PhosphoSitePlus	COSMIC	24.279	Down-regulation
AGC_RSK_RSKp70_RPS6KB1_ST	Q8TB45	DEPTOR	P23443	RPS6KB1	S389	V388M	388	Missense	proximal	-1	no	29.369	29.359	EPSD	COSMIC;GDSC;CCLE	24.279	Down-regulation
AGC_RSK_RSKp70_RPS6KB1_ST	Q8TB45	DEPTOR	P23443	RPS6KB1	S389	S389N	389	Missense	central	0	yes	29.369	0.000	EPSD	COSMIC	24.279	Loss
AGC_RSK_RSKp70_RPS6KB1_ST	Q8TB45	DEPTOR	P23443	RPS6KB1	S389	P396Q	396	Missense	distal	7	no	29.369	29.893	EPSD	COSMIC	24.279	Up-regulation
AGC_RSK_RSKp70_RPS6KB1_ST	Q8TB45	DEPTOR	P23443	RPS6KB1	S389	L391V	391	Missense	proximal	2	no	29.369	26.846	EPSD	COSMIC	24.279	Down-regulation
AGC_RSK_RSKp70_RPS6KB1_ST	P23443	RPS6KB1	P23443	RPS6KB1	S243	H245Y	245	Missense	proximal	2	no	25.912	23.226	EPSD	COSMIC	24.279	Loss
AGC_RSK_RSKp70_RPS6KB1_ST	P23443	RPS6KB1	P23443	RPS6KB1	S243	C240R	240	Missense	distal	-3	no	25.912	35.461	EPSD	COSMIC	24.279	Up-regulation
AGC_RSK_RSKp70_RPS6KB1_ST	P23443	RPS6KB1	P23443	RPS6KB1	T412	T412A	412	Missense	central	0	yes	34.773	0.000	PhosphoSitePlus	COSMIC	24.279	Loss
AGC_RSK_RSKp70_RPS6KB1_ST	P23443	RPS6KB1	P23443	RPS6KB1	T412	V414E	414	Missense	proximal	2	no	34.773	35.660	PhosphoSitePlus	COSMIC	24.279	Up-regulation
AGC_RSK_RSKp70_RPS6KB1_ST	P23443	RPS6KB1	P23443	RPS6KB1	S441	G440A	440	Missense	proximal	-1	no	31.447	31.467	EPSD	COSMIC	24.279	Up-regulation
AGC_RSK_RSKp70_RPS6KB1_ST	P23443	RPS6KB1	P23443	RPS6KB1	S441	P445L	445	Missense	distal	4	no	31.447	31.934	EPSD	COSMIC	24.279	Up-regulation
AGC_RSK_RSKp70_RPS6KB1_ST	P23443	RPS6KB1	P23443	RPS6KB1	S441	R436Q	436	Missense	distal	-5	no	31.447	19.472	EPSD	COSMIC	24.279	Loss
AGC_RSK_RSKp70_RPS6KB1_ST	O00418	EEF2K	P23443	RPS6KB1	S366	T364N	364	Missense	proximal	-2	no	37.526	38.130	PhosphoSitePlus	COSMIC	24.279	Up-regulation
AGC_RSK_RSKp70_RPS6KB1_ST	O00418	EEF2K	P23443	RPS6KB1	S396	S398C	398	Missense	proximal	2	no	24.361	21.576	EPSD	COSMIC	24.279	Loss
AGC_RSK_RSKp70_RPS6KB1_ST	O00418	EEF2K	P23443	RPS6KB1	S396	T389I	389	Missense	distal	-7	no	24.361	24.487	EPSD	COSMIC	24.279	Up-regulation
AGC_RSK_RSKp70_RPS6KB1_ST	O00418	EEF2K	P23443	RPS6KB1	S396	S399L	399	Missense	distal	3	no	24.361	22.661	EPSD	COSMIC	24.279	Loss
AGC_RSK_RSKp70_RPS6KB1_ST	O00418	EEF2K	P23443	RPS6KB1	S396	P394L	394	Missense	proximal	-2	no	24.361	22.596	EPSD	COSMIC;GDSC;CCLE	24.279	Loss
AGC_RSK_RSKp70_RPS6KB1_ST	O00418	EEF2K	P23443	RPS6KB1	S396	P394S	394	Missense	proximal	-2	no	24.361	22.455	EPSD	COSMIC	24.279	Loss
AGC_RSK_RSKp70_RPS6KB1_ST	O00418	EEF2K	P23443	RPS6KB1	S404	S398C	398	Missense	distal	-6	no	28.363	28.410	EPSD	COSMIC	24.279	Up-regulation
AGC_RSK_RSKp70_RPS6KB1_ST	O00418	EEF2K	P23443	RPS6KB1	S404	S399L	399	Missense	distal	-5	no	28.363	25.279	EPSD	COSMIC	24.279	Down-regulation
AGC_RSK_RSKp70_RPS6KB1_ST	O00418	EEF2K	P23443	RPS6KB1	S416	D417G	417	Missense	proximal	1	no	25.562	26.136	EPSD	COSMIC	24.279	Up-regulation
AGC_RSK_RSKp70_RPS6KB1_ST	O00418	EEF2K	P23443	RPS6KB1	S416	S416G	416	Missense	central	0	yes	25.562	0.000	EPSD	COSMIC;CCLE	24.279	Loss
AGC_RSK_RSKp70_RPS6KB1_ST	O00418	EEF2K	P23443	RPS6KB1	S435	R433Q	433	Missense	proximal	-2	no	26.043	26.846	EPSD	COSMIC	24.279	Up-regulation
AGC_RSK_RSKp70_RPS6KB1_ST	O00418	EEF2K	P23443	RPS6KB1	S438	R433Q	433	Missense	distal	-5	no	28.507	16.532	EPSD	COSMIC	24.279	Loss
AGC_RSK_RSKp70_RPS6KB1_ST	O00418	EEF2K	P23443	RPS6KB1	S445	E446D	446	Missense	proximal	1	no	28.174	27.529	EPSD	COSMIC	24.279	Down-regulation
AGC_RSK_RSKp70_RPS6KB1_ST	O00418	EEF2K	P23443	RPS6KB1	S462	E455D	455	Missense	distal	-7	no	31.229	31.494	EPSD	COSMIC	24.279	Up-regulation
AGC_RSK_RSKp70_RPS6KB1_ST	O00418	EEF2K	P23443	RPS6KB1	S470	G476C	476	Missense	distal	6	no	27.506	26.337	EPSD	COSMIC	24.279	Down-regulation
AGC_RSK_RSKp70_RPS6KB1_ST	O00418	EEF2K	P23443	RPS6KB1	S492	R493C	493	Missense	proximal	1	no	28.251	29.197	EPSD	COSMIC	24.279	Up-regulation
AGC_RSK_RSKp70_RPS6KB1_ST	P03372	ESR1	P23443	RPS6KB1	S118	P113L	113	Missense	distal	-5	no	25.450	25.304	EPSD	COSMIC	24.279	Down-regulation
AGC_RSK_RSKp70_RPS6KB1_ST	P03372	ESR1	P23443	RPS6KB1	S118	P113Q	113	Missense	distal	-5	no	25.450	21.953	EPSD	COSMIC	24.279	Loss
AGC_RSK_RSKp70_RPS6KB1_ST	P03372	ESR1	P23443	RPS6KB1	S118	L117Q	117	Missense	proximal	-1	no	25.450	25.458	EPSD	COSMIC	24.279	Up-regulation
AGC_RSK_RSKp70_RPS6KB1_ST	P03372	ESR1	P23443	RPS6KB1	S118	H112L	112	Missense	distal	-6	no	25.450	25.472	EPSD	COSMIC	24.279	Up-regulation
AGC_RSK_RSKp70_RPS6KB1_ST	P03372	ESR1	P23443	RPS6KB1	S118	S118P	118	Missense	central	0	yes	25.450	0.000	EPSD	COSMIC	24.279	Loss
AGC_RSK_RSKp70_RPS6KB1_ST	P03372	ESR1	P23443	RPS6KB1	S154	A148E	148	Missense	distal	-6	no	24.680	24.662	EPSD	COSMIC	24.279	Down-regulation
AGC_RSK_RSKp70_RPS6KB1_ST	P03372	ESR1	P23443	RPS6KB1	S154	R151K	151	Missense	distal	-3	no	24.680	17.061	EPSD	COSMIC	24.279	Loss
AGC_RSK_RSKp70_RPS6KB1_ST	P03372	ESR1	P23443	RPS6KB1	S154	P147Q	147	Missense	distal	-7	no	24.680	24.581	EPSD	COSMIC	24.279	Down-regulation
AGC_RSK_RSKp70_RPS6KB1_ST	P03372	ESR1	P23443	RPS6KB1	S154	R158C	158	Missense	distal	4	no	24.680	24.032	EPSD	COSMIC	24.279	Loss
AGC_RSK_RSKp70_RPS6KB1_ST	P03372	ESR1	P23443	RPS6KB1	S154	Q159L	159	Missense	distal	5	no	24.680	25.206	EPSD	COSMIC	24.279	Up-regulation
AGC_RSK_RSKp70_RPS6KB1_ST	P03372	ESR1	P23443	RPS6KB1	S154	R157Q	157	Missense	distal	3	no	24.680	23.354	EPSD	COSMIC	24.279	Loss
AGC_RSK_RSKp70_RPS6KB1_ST	P03372	ESR1	P23443	RPS6KB1	S154	N156T	156	Missense	proximal	2	no	24.680	27.285	EPSD	COSMIC	24.279	Up-regulation
AGC_RSK_RSKp70_RPS6KB1_ST	P03372	ESR1	P23443	RPS6KB1	S154	G160D	160	Missense	distal	6	no	24.680	23.197	EPSD	COSMIC	24.279	Loss
AGC_RSK_RSKp70_RPS6KB1_ST	P03372	ESR1	P23443	RPS6KB1	S154	P152S	152	Missense	proximal	-2	no	24.680	22.774	EPSD	COSMIC	24.279	Loss
AGC_RSK_RSKp70_RPS6KB1_ST	P03372	ESR1	P23443	RPS6KB1	S154	P152L	152	Missense	proximal	-2	no	24.680	22.916	EPSD	COSMIC	24.279	Loss
AGC_RSK_RSKp70_RPS6KB1_ST	P03372	ESR1	P23443	RPS6KB1	S167	G172R	172	Missense	distal	5	no	39.842	39.081	PhosphoSitePlus	COSMIC	24.279	Down-regulation
AGC_RSK_RSKp70_RPS6KB1_ST	P03372	ESR1	P23443	RPS6KB1	S167	M174I	174	Missense	distal	7	no	39.842	39.506	PhosphoSitePlus	COSMIC	24.279	Down-regulation
AGC_RSK_RSKp70_RPS6KB1_ST	P03372	ESR1	P23443	RPS6KB1	S167	D170Y	170	Missense	distal	3	no	39.842	39.522	PhosphoSitePlus	COSMIC	24.279	Down-regulation
AGC_RSK_RSKp70_RPS6KB1_ST	P03372	ESR1	P23443	RPS6KB1	S167	G160D	160	Missense	distal	-7	no	39.842	39.882	PhosphoSitePlus	COSMIC	24.279	Up-regulation
AGC_RSK_RSKp70_RPS6KB1_ST	P03372	ESR1	P23443	RPS6KB1	S236	R241G	241	Missense	distal	5	no	28.484	29.245	EPSD	COSMIC	24.279	Up-regulation
AGC_RSK_RSKp70_RPS6KB1_ST	P03372	ESR1	P23443	RPS6KB1	S236	R241W	241	Missense	distal	5	no	28.484	26.618	EPSD	COSMIC	24.279	Down-regulation
AGC_RSK_RSKp70_RPS6KB1_ST	P03372	ESR1	P23443	RPS6KB1	S236	R233G	233	Missense	distal	-3	no	28.484	20.660	EPSD	COSMIC	24.279	Loss
AGC_RSK_RSKp70_RPS6KB1_ST	P03372	ESR1	P23443	RPS6KB1	S236	C237Y	237	Missense	proximal	1	no	28.484	28.111	EPSD	COSMIC	24.279	Down-regulation
AGC_RSK_RSKp70_RPS6KB1_ST	P03372	ESR1	P23443	RPS6KB1	S236	Q238H	238	Missense	proximal	2	no	28.484	30.812	EPSD	COSMIC;CCLE	24.279	Up-regulation
AGC_RSK_RSKp70_RPS6KB1_ST	P03372	ESR1	P23443	RPS6KB1	S236	R243L	243	Missense	distal	7	no	28.484	28.501	EPSD	COSMIC	24.279	Up-regulation
AGC_RSK_RSKp70_RPS6KB1_ST	P03372	ESR1	P23443	RPS6KB1	S282	G276S	276	Missense	distal	-6	no	25.502	25.466	EPSD	COSMIC	24.279	Down-regulation
AGC_RSK_RSKp70_RPS6KB1_ST	P03372	ESR1	P23443	RPS6KB1	S282	G284E	284	Missense	proximal	2	no	25.502	24.500	EPSD	COSMIC	24.279	Down-regulation
AGC_RSK_RSKp70_RPS6KB1_ST	P03372	ESR1	P23443	RPS6KB1	S282	E279V	279	Missense	distal	-3	no	25.502	21.096	EPSD	COSMIC	24.279	Loss
AGC_RSK_RSKp70_RPS6KB1_ST	P03372	ESR1	P23443	RPS6KB1	S282	E275V	275	Missense	distal	-7	no	25.502	25.888	EPSD	COSMIC	24.279	Up-regulation
AGC_RSK_RSKp70_RPS6KB1_ST	P03372	ESR1	P23443	RPS6KB1	S282	G276D	276	Missense	distal	-6	no	25.502	25.530	EPSD	COSMIC;GDSC;CCLE	24.279	Up-regulation
AGC_RSK_RSKp70_RPS6KB1_ST	P03372	ESR1	P23443	RPS6KB1	S282	R277S	277	Missense	distal	-5	no	25.502	19.963	EPSD	COSMIC	24.279	Loss
AGC_RSK_RSKp70_RPS6KB1_ST	P03372	ESR1	P23443	RPS6KB1	S282	S282C	282	Missense	central	0	yes	25.502	0.000	EPSD	COSMIC	24.279	Loss
AGC_RSK_RSKp70_RPS6KB1_ST	P03372	ESR1	P23443	RPS6KB1	S282	A288T	288	Missense	distal	6	no	25.502	26.691	EPSD	COSMIC	24.279	Up-regulation
AGC_RSK_RSKp70_RPS6KB1_ST	P03372	ESR1	P23443	RPS6KB1	S282	R287H	287	Missense	distal	5	no	25.502	25.803	EPSD	COSMIC	24.279	Up-regulation
AGC_RSK_RSKp70_RPS6KB1_ST	P03372	ESR1	P23443	RPS6KB1	S282	R287C	287	Missense	distal	5	no	25.502	24.002	EPSD	COSMIC	24.279	Loss
AGC_RSK_RSKp70_RPS6KB1_ST	P03372	ESR1	P23443	RPS6KB1	S282	G284C	284	Missense	proximal	2	no	25.502	24.526	EPSD	COSMIC	24.279	Down-regulation
AGC_RSK_RSKp70_RPS6KB1_ST	P03372	ESR1	P23443	RPS6KB1	S341	S338G	338	Missense	distal	-3	no	27.403	29.063	EPSD	COSMIC	24.279	Up-regulation
AGC_RSK_RSKp70_RPS6KB1_ST	P03372	ESR1	P23443	RPS6KB1	S341	S338R	338	Missense	distal	-3	no	27.403	36.887	EPSD	COSMIC	24.279	Up-regulation
AGC_RSK_RSKp70_RPS6KB1_ST	P03372	ESR1	P23443	RPS6KB1	S341	T347I	347	Missense	distal	6	no	27.403	26.211	EPSD	COSMIC	24.279	Down-regulation
AGC_RSK_RSKp70_RPS6KB1_ST	P03372	ESR1	P23443	RPS6KB1	S341	M343L	343	Missense	proximal	2	no	27.403	27.974	EPSD	COSMIC	24.279	Up-regulation
AGC_RSK_RSKp70_RPS6KB1_ST	P03372	ESR1	P23443	RPS6KB1	S559	G557R	557	Missense	proximal	-2	no	25.754	26.620	EPSD	COSMIC	24.279	Up-regulation
AGC_RSK_RSKp70_RPS6KB1_ST	P03372	ESR1	P23443	RPS6KB1	S559	D564Y	564	Missense	distal	5	no	25.754	24.349	EPSD	COSMIC	24.279	Down-regulation
AGC_RSK_RSKp70_RPS6KB1_ST	P03372	ESR1	P23443	RPS6KB1	S559	V560M	560	Missense	proximal	1	no	25.754	25.285	EPSD	COSMIC	24.279	Down-regulation
AGC_RSK_RSKp70_RPS6KB1_ST	P03372	ESR1	P23443	RPS6KB1	S559	D564N	564	Missense	distal	5	no	25.754	25.276	EPSD	COSMIC	24.279	Down-regulation
AGC_RSK_RSKp70_RPS6KB1_ST	Q16873	LTC4S	P23443	RPS6KB1	S36	A29V	29	Missense	distal	-7	no	36.794	36.984	PhosphoSitePlus	COSMIC	24.279	Up-regulation
AGC_RSK_RSKp70_RPS6KB1_ST	Q05195	MXD1	P23443	RPS6KB1	S32	N38K	38	Missense	distal	6	no	24.498	25.225	EPSD	COSMIC	24.279	Up-regulation
AGC_RSK_RSKp70_RPS6KB1_ST	Q05195	MXD1	P23443	RPS6KB1	S89	R91Q	91	Missense	proximal	2	no	25.487	23.680	EPSD	COSMIC	24.279	Loss
AGC_RSK_RSKp70_RPS6KB1_ST	Q05195	MXD1	P23443	RPS6KB1	S89	S90I	90	Missense	proximal	1	no	25.487	26.196	EPSD	COSMIC	24.279	Up-regulation
AGC_RSK_RSKp70_RPS6KB1_ST	Q05195	MXD1	P23443	RPS6KB1	S89	E88K	88	Missense	proximal	-1	no	25.487	25.551	EPSD	COSMIC	24.279	Up-regulation
AGC_RSK_RSKp70_RPS6KB1_ST	Q05195	MXD1	P23443	RPS6KB1	S89	R91G	91	Missense	proximal	2	no	25.487	25.782	EPSD	COSMIC;GDSC;CCLE	24.279	Up-regulation
AGC_RSK_RSKp70_RPS6KB1_ST	Q05195	MXD1	P23443	RPS6KB1	T93	L97V	97	Missense	distal	4	no	25.303	24.537	EPSD	COSMIC	24.279	Down-regulation
AGC_RSK_RSKp70_RPS6KB1_ST	Q05195	MXD1	P23443	RPS6KB1	T93	R91Q	91	Missense	proximal	-2	no	25.303	26.105	EPSD	COSMIC	24.279	Up-regulation
AGC_RSK_RSKp70_RPS6KB1_ST	Q05195	MXD1	P23443	RPS6KB1	T93	S90I	90	Missense	distal	-3	no	25.303	19.874	EPSD	COSMIC	24.279	Loss
AGC_RSK_RSKp70_RPS6KB1_ST	Q05195	MXD1	P23443	RPS6KB1	T93	E88K	88	Missense	distal	-5	no	25.303	24.111	EPSD	COSMIC	24.279	Loss
AGC_RSK_RSKp70_RPS6KB1_ST	Q05195	MXD1	P23443	RPS6KB1	T93	R91G	91	Missense	proximal	-2	no	25.303	24.437	EPSD	COSMIC;GDSC;CCLE	24.279	Down-regulation
AGC_RSK_RSKp70_RPS6KB1_ST	Q05195	MXD1	P23443	RPS6KB1	T94	L97V	97	Missense	distal	3	no	29.109	28.741	EPSD	COSMIC	24.279	Down-regulation
AGC_RSK_RSKp70_RPS6KB1_ST	Q05195	MXD1	P23443	RPS6KB1	T94	R91Q	91	Missense	distal	-3	no	29.109	10.053	EPSD	COSMIC	24.279	Loss
AGC_RSK_RSKp70_RPS6KB1_ST	Q05195	MXD1	P23443	RPS6KB1	T94	S90I	90	Missense	distal	-4	no	29.109	28.247	EPSD	COSMIC	24.279	Down-regulation
AGC_RSK_RSKp70_RPS6KB1_ST	Q05195	MXD1	P23443	RPS6KB1	T94	E88K	88	Missense	distal	-6	no	29.109	29.101	EPSD	COSMIC	24.279	Down-regulation
AGC_RSK_RSKp70_RPS6KB1_ST	Q05195	MXD1	P23443	RPS6KB1	T94	R91G	91	Missense	distal	-3	no	29.109	21.285	EPSD	COSMIC;GDSC;CCLE	24.279	Loss
AGC_RSK_RSKp70_RPS6KB1_ST	Q05195	MXD1	P23443	RPS6KB1	S96	L97V	97	Missense	proximal	1	no	24.803	24.372	EPSD	COSMIC	24.279	Down-regulation
AGC_RSK_RSKp70_RPS6KB1_ST	Q05195	MXD1	P23443	RPS6KB1	S96	R91Q	91	Missense	distal	-5	no	24.803	12.828	EPSD	COSMIC	24.279	Loss
AGC_RSK_RSKp70_RPS6KB1_ST	Q05195	MXD1	P23443	RPS6KB1	S96	S90I	90	Missense	distal	-6	no	24.803	24.864	EPSD	COSMIC	24.279	Up-regulation
AGC_RSK_RSKp70_RPS6KB1_ST	Q05195	MXD1	P23443	RPS6KB1	S96	R91G	91	Missense	distal	-5	no	24.803	17.559	EPSD	COSMIC;GDSC;CCLE	24.279	Loss
AGC_RSK_RSKp70_RPS6KB1_ST	Q05195	MXD1	P23443	RPS6KB1	S145	E139Q	139	Missense	distal	-6	no	38.496	38.519	PhosphoSitePlus	COSMIC	24.279	Up-regulation
AGC_RSK_RSKp70_RPS6KB1_ST	Q05195	MXD1	P23443	RPS6KB1	S145	S151F	151	Missense	distal	6	no	38.496	36.482	PhosphoSitePlus	COSMIC	24.279	Down-regulation
AGC_RSK_RSKp70_RPS6KB1_ST	Q05195	MXD1	P23443	RPS6KB1	S145	R142Q	142	Missense	distal	-3	no	38.496	19.441	PhosphoSitePlus	COSMIC	24.279	Loss
AGC_RSK_RSKp70_RPS6KB1_ST	Q05195	MXD1	P23443	RPS6KB1	S145	S145F	145	Missense	central	0	yes	38.496	0.000	PhosphoSitePlus	COSMIC	24.279	Loss
AGC_RSK_RSKp70_RPS6KB1_ST	Q05195	MXD1	P23443	RPS6KB1	S145	T149I	149	Missense	distal	4	no	38.496	38.058	PhosphoSitePlus	COSMIC	24.279	Down-regulation
AGC_RSK_RSKp70_RPS6KB1_ST	Q05195	MXD1	P23443	RPS6KB1	S194	M192I	192	Missense	proximal	-2	no	27.511	27.892	EPSD	COSMIC	24.279	Up-regulation
AGC_RSK_RSKp70_RPS6KB1_ST	Q05195	MXD1	P23443	RPS6KB1	S194	S191R	191	Missense	distal	-3	no	27.511	36.994	EPSD	COSMIC	24.279	Up-regulation
AGC_RSK_RSKp70_RPS6KB1_ST	Q05195	MXD1	P23443	RPS6KB1	S194	R189W	189	Missense	distal	-5	no	27.511	15.547	EPSD	COSMIC	24.279	Loss
AGC_RSK_RSKp70_RPS6KB1_ST	O94763	URI1	P23443	RPS6KB1	S13	P9L	9	Missense	distal	-4	no	30.026	30.938	EPSD	COSMIC	24.279	Up-regulation
AGC_RSK_RSKp70_RPS6KB1_ST	O94763	URI1	P23443	RPS6KB1	S13	E7K	7	Missense	distal	-6	no	30.026	30.019	EPSD	COSMIC	24.279	Down-regulation
AGC_RSK_RSKp70_RPS6KB1_ST	O94763	URI1	P23443	RPS6KB1	T241	D240N	240	Missense	proximal	-1	no	25.106	25.073	EPSD	COSMIC	24.279	Down-regulation
AGC_RSK_RSKp70_RPS6KB1_ST	O94763	URI1	P23443	RPS6KB1	T350	P343H	343	Missense	distal	-7	no	37.604	37.489	EPSD	COSMIC	24.279	Down-regulation
AGC_RSK_RSKp70_RPS6KB1_ST	O94763	URI1	P23443	RPS6KB1	S359	A365T	365	Missense	distal	6	no	25.048	26.237	EPSD	COSMIC	24.279	Up-regulation
AGC_RSK_RSKp70_RPS6KB1_ST	O94763	URI1	P23443	RPS6KB1	S372	A365T	365	Missense	distal	-7	no	47.363	47.270	PhosphoSitePlus	COSMIC	24.279	Down-regulation
AGC_RSK_RSKp70_RPS6KB1_ST	O94763	URI1	P23443	RPS6KB1	S372	R367H	367	Missense	distal	-5	no	47.363	44.508	PhosphoSitePlus	COSMIC	24.279	Down-regulation
AGC_RSK_RSKp70_RPS6KB1_ST	O94763	URI1	P23443	RPS6KB1	S372	S372C	372	Missense	central	0	yes	47.363	0.000	PhosphoSitePlus	COSMIC	24.279	Loss
AGC_RSK_RSKp70_RPS6KB1_ST	O94763	URI1	P23443	RPS6KB1	T373	R367H	367	Missense	distal	-6	no	24.961	24.975	EPSD	COSMIC	24.279	Up-regulation
AGC_RSK_RSKp70_RPS6KB1_ST	O94763	URI1	P23443	RPS6KB1	T373	S372C	372	Missense	proximal	-1	no	24.961	25.063	EPSD	COSMIC	24.279	Up-regulation
AGC_RSK_RSKp70_RPS6KB1_ST	P49959	MRE11	P23443	RPS6KB1	S264	Q259R	259	Missense	distal	-5	no	12.307	24.282	EPSD	COSMIC	24.279	Gain
AGC_RSK_RSKp70_RPS6KB1_ST	P49959	MRE11	P23443	RPS6KB1	S355	Q357K	357	Missense	proximal	2	no	27.539	30.296	EPSD	COSMIC	24.279	Up-regulation
AGC_RSK_RSKp70_RPS6KB1_ST	P49959	MRE11	P23443	RPS6KB1	S355	R351H	351	Missense	distal	-4	no	27.539	27.083	EPSD	COSMIC;GDSC	24.279	Down-regulation
AGC_RSK_RSKp70_RPS6KB1_ST	P49959	MRE11	P23443	RPS6KB1	S355	R349W	349	Missense	distal	-6	no	27.539	27.602	EPSD	COSMIC	24.279	Up-regulation
AGC_RSK_RSKp70_RPS6KB1_ST	P49959	MRE11	P23443	RPS6KB1	S355	E359D	359	Missense	distal	4	no	27.539	27.631	EPSD	COSMIC	24.279	Up-regulation
AGC_RSK_RSKp70_RPS6KB1_ST	P49959	MRE11	P23443	RPS6KB1	S355	R349L	349	Missense	distal	-6	no	27.539	27.575	EPSD	COSMIC	24.279	Up-regulation
AGC_RSK_RSKp70_RPS6KB1_ST	P49959	MRE11	P23443	RPS6KB1	S355	S355F	355	Missense	central	0	yes	27.539	0.000	EPSD	COSMIC	24.279	Loss
AGC_RSK_RSKp70_RPS6KB1_ST	P49959	MRE11	P23443	RPS6KB1	S355	N354I	354	Missense	proximal	-1	no	27.539	27.520	EPSD	COSMIC	24.279	Down-regulation
AGC_RSK_RSKp70_RPS6KB1_ST	P49959	MRE11	P23443	RPS6KB1	S355	E348V	348	Missense	distal	-7	no	27.539	27.924	EPSD	COSMIC	24.279	Up-regulation
AGC_RSK_RSKp70_RPS6KB1_ST	P49959	MRE11	P23443	RPS6KB1	S533	Q532E	532	Missense	proximal	-1	no	33.717	33.666	EPSD	COSMIC	24.279	Down-regulation
AGC_RSK_RSKp70_RPS6KB1_ST	P49959	MRE11	P23443	RPS6KB1	S533	A528T	528	Missense	distal	-5	no	33.717	33.853	EPSD	COSMIC	24.279	Up-regulation
AGC_RSK_RSKp70_RPS6KB1_ST	P49959	MRE11	P23443	RPS6KB1	S533	S531Y	531	Missense	proximal	-2	no	33.717	34.660	EPSD	COSMIC	24.279	Up-regulation
AGC_RSK_RSKp70_RPS6KB1_ST	P49959	MRE11	P23443	RPS6KB1	S533	A526V	526	Missense	distal	-7	no	33.717	33.907	EPSD	COSMIC	24.279	Up-regulation
AGC_RSK_RSKp70_RPS6KB1_ST	P49959	MRE11	P23443	RPS6KB1	S590	S586L	586	Missense	distal	-4	no	25.226	24.473	EPSD	COSMIC	24.279	Down-regulation
AGC_RSK_RSKp70_RPS6KB1_ST	P49959	MRE11	P23443	RPS6KB1	S590	A595S	595	Missense	distal	5	no	25.226	26.954	EPSD	COSMIC	24.279	Up-regulation
AGC_RSK_RSKp70_RPS6KB1_ST	P49959	MRE11	P23443	RPS6KB1	S590	S584L	584	Missense	distal	-6	no	25.226	25.270	EPSD	COSMIC	24.279	Up-regulation
AGC_RSK_RSKp70_RPS6KB1_ST	P49959	MRE11	P23443	RPS6KB1	S590	G588R	588	Missense	proximal	-2	no	25.226	26.092	EPSD	COSMIC	24.279	Up-regulation
AGC_RSK_RSKp70_RPS6KB1_ST	P49959	MRE11	P23443	RPS6KB1	S590	Q591E	591	Missense	proximal	1	no	25.226	25.855	EPSD	COSMIC	24.279	Up-regulation
AGC_RSK_RSKp70_RPS6KB1_ST	P49959	MRE11	P23443	RPS6KB1	S590	G593K	593	Missense	distal	3	no	25.226	28.681	EPSD	COSMIC	24.279	Up-regulation
AGC_RSK_RSKp70_RPS6KB1_ST	P49959	MRE11	P23443	RPS6KB1	S590	G593R	593	Missense	distal	3	no	25.226	27.653	EPSD	COSMIC;GDSC	24.279	Up-regulation
AGC_RSK_RSKp70_RPS6KB1_ST	P49959	MRE11	P23443	RPS6KB1	S590	G593E	593	Missense	distal	3	no	25.226	29.455	EPSD	COSMIC;GDSC	24.279	Up-regulation
AGC_RSK_RSKp70_RPS6KB1_ST	P49959	MRE11	P23443	RPS6KB1	S590	A595V	595	Missense	distal	5	no	25.226	24.562	EPSD	COSMIC	24.279	Down-regulation
AGC_RSK_RSKp70_RPS6KB1_ST	P49959	MRE11	P23443	RPS6KB1	T597	R604C	604	Missense	distal	7	no	38.224	37.222	PhosphoSitePlus	COSMIC	24.279	Down-regulation
AGC_RSK_RSKp70_RPS6KB1_ST	P49959	MRE11	P23443	RPS6KB1	T597	A595S	595	Missense	proximal	-2	no	38.224	37.148	PhosphoSitePlus	COSMIC	24.279	Down-regulation
AGC_RSK_RSKp70_RPS6KB1_ST	P49959	MRE11	P23443	RPS6KB1	T597	R604S	604	Missense	distal	7	no	38.224	38.757	PhosphoSitePlus	COSMIC	24.279	Up-regulation
AGC_RSK_RSKp70_RPS6KB1_ST	P49959	MRE11	P23443	RPS6KB1	T597	Q591E	591	Missense	distal	-6	no	38.224	38.201	PhosphoSitePlus	COSMIC	24.279	Down-regulation
AGC_RSK_RSKp70_RPS6KB1_ST	P49959	MRE11	P23443	RPS6KB1	T597	T603I	603	Missense	distal	6	no	38.224	37.031	PhosphoSitePlus	COSMIC	24.279	Down-regulation
AGC_RSK_RSKp70_RPS6KB1_ST	P49959	MRE11	P23443	RPS6KB1	T597	G593K	593	Missense	distal	-4	no	38.224	41.158	PhosphoSitePlus	COSMIC	24.279	Up-regulation
AGC_RSK_RSKp70_RPS6KB1_ST	P49959	MRE11	P23443	RPS6KB1	T597	G593R	593	Missense	distal	-4	no	38.224	40.213	PhosphoSitePlus	COSMIC;GDSC	24.279	Up-regulation
AGC_RSK_RSKp70_RPS6KB1_ST	P49959	MRE11	P23443	RPS6KB1	T597	G593E	593	Missense	distal	-4	no	38.224	39.767	PhosphoSitePlus	COSMIC;GDSC	24.279	Up-regulation
AGC_RSK_RSKp70_RPS6KB1_ST	P49959	MRE11	P23443	RPS6KB1	T597	A595V	595	Missense	proximal	-2	no	38.224	38.800	PhosphoSitePlus	COSMIC	24.279	Up-regulation
AGC_RSK_RSKp70_RPS6KB1_ST	P49959	MRE11	P23443	RPS6KB1	S641	N634S	634	Missense	distal	-7	no	26.707	26.634	EPSD	COSMIC	24.279	Down-regulation
AGC_RSK_RSKp70_RPS6KB1_ST	P49959	MRE11	P23443	RPS6KB1	S668	I674N	674	Missense	distal	6	no	27.686	27.352	EPSD	COSMIC	24.279	Down-regulation
AGC_RSK_RSKp70_RPS6KB1_ST	P49959	MRE11	P23443	RPS6KB1	S670	I674N	674	Missense	distal	4	no	32.024	32.142	EPSD	COSMIC	24.279	Up-regulation
AGC_RSK_RSKp70_RPS6KB1_ST	P49959	MRE11	P23443	RPS6KB1	S672	Q679K	679	Missense	distal	7	no	28.601	28.334	EPSD	COSMIC	24.279	Down-regulation
AGC_RSK_RSKp70_RPS6KB1_ST	P49959	MRE11	P23443	RPS6KB1	S672	I674N	674	Missense	proximal	2	no	28.601	28.338	EPSD	COSMIC	24.279	Down-regulation
AGC_RSK_RSKp70_RPS6KB1_ST	P49959	MRE11	P23443	RPS6KB1	S672	Q679E	679	Missense	distal	7	no	28.601	28.307	EPSD	COSMIC	24.279	Down-regulation
AGC_RSK_RSKp70_RPS6KB1_ST	P49959	MRE11	P23443	RPS6KB1	S676	Q679K	679	Missense	distal	3	no	27.419	29.773	EPSD	COSMIC	24.279	Up-regulation
AGC_RSK_RSKp70_RPS6KB1_ST	P49959	MRE11	P23443	RPS6KB1	S676	G683R	683	Missense	distal	7	no	27.419	27.264	EPSD	COSMIC	24.279	Down-regulation
AGC_RSK_RSKp70_RPS6KB1_ST	P49959	MRE11	P23443	RPS6KB1	S676	I674N	674	Missense	proximal	-2	no	27.419	28.011	EPSD	COSMIC	24.279	Up-regulation
AGC_RSK_RSKp70_RPS6KB1_ST	P49959	MRE11	P23443	RPS6KB1	S676	Q679E	679	Missense	distal	3	no	27.419	30.547	EPSD	COSMIC	24.279	Up-regulation
AGC_RSK_RSKp70_RPS6KB1_ST	P49959	MRE11	P23443	RPS6KB1	S676	G683V	683	Missense	distal	7	no	27.419	26.880	EPSD	COSMIC	24.279	Down-regulation
AGC_RSK_RSKp70_RPS6KB1_ST	P49959	MRE11	P23443	RPS6KB1	S676	V680I	680	Missense	distal	4	no	27.419	27.444	EPSD	COSMIC	24.279	Up-regulation
AGC_RSK_RSKp70_RPS6KB1_ST	P49959	MRE11	P23443	RPS6KB1	S701	N699K	699	Missense	proximal	-2	no	26.562	25.875	EPSD	COSMIC	24.279	Down-regulation
AGC_RSK_RSKp70_RPS6KB1_ST	P49959	MRE11	P23443	RPS6KB1	S701	R705I	705	Missense	distal	4	no	26.562	26.576	EPSD	COSMIC	24.279	Up-regulation
AGC_RSK_RSKp70_RPS6KB1_ST	P49959	MRE11	P23443	RPS6KB1	S701	P696S	696	Missense	distal	-5	no	26.562	29.501	EPSD	COSMIC	24.279	Up-regulation
AGC_RSK_RSKp70_RPS6KB1_ST	P49959	MRE11	P23443	RPS6KB1	S701	D695Y	695	Missense	distal	-6	no	26.562	26.580	EPSD	COSMIC	24.279	Up-regulation
AGC_RSK_RSKp70_RPS6KB1_ST	P49959	MRE11	P23443	RPS6KB1	S701	M698V	698	Missense	distal	-3	no	26.562	17.308	EPSD	COSMIC	24.279	Loss
AGC_RSK_RSKp70_RPS6KB1_ST	P49959	MRE11	P23443	RPS6KB1	S701	D694G	694	Missense	distal	-7	no	26.562	26.522	EPSD	COSMIC	24.279	Down-regulation
AGC_RSK_RSKp70_RPS6KB1_ST	P49959	MRE11	P23443	RPS6KB1	S701	R707I	707	Missense	distal	6	no	26.562	26.016	EPSD	COSMIC	24.279	Down-regulation
AGC_RSK_RSKp70_RPS6KB1_ST	P49959	MRE11	P23443	RPS6KB1	S701	R704I	704	Missense	distal	3	no	26.562	26.320	EPSD	COSMIC	24.279	Down-regulation
AGC_RSK_RSKp70_RPS6KB1_ST	P49959	MRE11	P23443	RPS6KB1	S701	D694Y	694	Missense	distal	-7	no	26.562	26.615	EPSD	COSMIC	24.279	Up-regulation
AGC_RSK_RSKp70_RPS6KB1_ST	P27708	CAD	P23443	RPS6KB1	S1069	P1063H	1063	Missense	distal	-6	no	25.150	25.120	EPSD	COSMIC	24.279	Down-regulation
AGC_RSK_RSKp70_RPS6KB1_ST	P27708	CAD	P23443	RPS6KB1	S1069	R1075C	1075	Missense	distal	6	no	25.150	24.724	EPSD	COSMIC	24.279	Down-regulation
AGC_RSK_RSKp70_RPS6KB1_ST	P27708	CAD	P23443	RPS6KB1	S1069	E1067D	1067	Missense	proximal	-2	no	25.150	25.532	EPSD	COSMIC	24.279	Up-regulation
AGC_RSK_RSKp70_RPS6KB1_ST	P27708	CAD	P23443	RPS6KB1	S1118	S1112C	1112	Missense	distal	-6	no	25.410	25.457	EPSD	COSMIC	24.279	Up-regulation
AGC_RSK_RSKp70_RPS6KB1_ST	P27708	CAD	P23443	RPS6KB1	S1227	P1224H	1224	Missense	distal	-3	no	19.003	28.136	EPSD	COSMIC	24.279	Gain
AGC_RSK_RSKp70_RPS6KB1_ST	P27708	CAD	P23443	RPS6KB1	S1267	V1263L	1263	Missense	distal	-4	no	24.091	25.448	EPSD	COSMIC	24.279	Gain
AGC_RSK_RSKp70_RPS6KB1_ST	P27708	CAD	P23443	RPS6KB1	S1267	A1272T	1272	Missense	distal	5	no	24.091	24.934	EPSD	COSMIC	24.279	Gain
AGC_RSK_RSKp70_RPS6KB1_ST	P27708	CAD	P23443	RPS6KB1	S1337	P1330L	1330	Missense	distal	-7	no	26.498	26.434	EPSD	COSMIC	24.279	Down-regulation
AGC_RSK_RSKp70_RPS6KB1_ST	P27708	CAD	P23443	RPS6KB1	S1337	A1344V	1344	Missense	distal	7	no	26.498	25.893	EPSD	COSMIC	24.279	Down-regulation
AGC_RSK_RSKp70_RPS6KB1_ST	P27708	CAD	P23443	RPS6KB1	S1337	S1341G	1341	Missense	distal	4	no	26.498	24.905	EPSD	COSMIC	24.279	Down-regulation
AGC_RSK_RSKp70_RPS6KB1_ST	P27708	CAD	P23443	RPS6KB1	S1406	R1403Q	1403	Missense	distal	-3	no	27.501	8.445	EPSD	COSMIC	24.279	Loss
AGC_RSK_RSKp70_RPS6KB1_ST	P27708	CAD	P23443	RPS6KB1	S1406	R1404H	1404	Missense	proximal	-2	no	27.501	27.430	EPSD	COSMIC	24.279	Down-regulation
AGC_RSK_RSKp70_RPS6KB1_ST	P27708	CAD	P23443	RPS6KB1	S1406	G1399E	1399	Missense	distal	-7	no	27.501	27.276	EPSD	COSMIC	24.279	Down-regulation
AGC_RSK_RSKp70_RPS6KB1_ST	P27708	CAD	P23443	RPS6KB1	S1406	A1400P	1400	Missense	distal	-6	no	27.501	27.515	EPSD	COSMIC	24.279	Up-regulation
AGC_RSK_RSKp70_RPS6KB1_ST	P27708	CAD	P23443	RPS6KB1	S1406	R1403W	1403	Missense	distal	-3	no	27.501	12.485	EPSD	COSMIC	24.279	Loss
AGC_RSK_RSKp70_RPS6KB1_ST	P27708	CAD	P23443	RPS6KB1	S1423	V1424M	1424	Missense	proximal	1	no	27.176	26.707	EPSD	COSMIC	24.279	Down-regulation
AGC_RSK_RSKp70_RPS6KB1_ST	P27708	CAD	P23443	RPS6KB1	S1458	P1465S	1465	Missense	distal	7	no	30.296	30.770	EPSD	COSMIC	24.279	Up-regulation
AGC_RSK_RSKp70_RPS6KB1_ST	P27708	CAD	P23443	RPS6KB1	S1458	C1455F	1455	Missense	distal	-3	no	30.296	26.691	EPSD	COSMIC	24.279	Down-regulation
AGC_RSK_RSKp70_RPS6KB1_ST	P27708	CAD	P23443	RPS6KB1	S1859	H1856Y	1856	Missense	distal	-3	no	36.039	22.689	PhosphoSitePlus	COSMIC	24.279	Loss
AGC_RSK_RSKp70_RPS6KB1_ST	P27708	CAD	P23443	RPS6KB1	S1859	D1860N	1860	Missense	proximal	1	no	36.039	35.044	PhosphoSitePlus	COSMIC	24.279	Down-regulation
AGC_RSK_RSKp70_RPS6KB1_ST	P27708	CAD	P23443	RPS6KB1	S1859	R1857Q	1857	Missense	proximal	-2	no	36.039	36.841	PhosphoSitePlus	COSMIC	24.279	Up-regulation
AGC_RSK_RSKp70_RPS6KB1_ST	P27708	CAD	P23443	RPS6KB1	S1859	R1854Q	1854	Missense	distal	-5	no	36.039	24.064	PhosphoSitePlus	COSMIC	24.279	Loss
AGC_RSK_RSKp70_RPS6KB1_ST	P27708	CAD	P23443	RPS6KB1	S1977	R1975L	1975	Missense	proximal	-2	no	30.294	29.791	EPSD	COSMIC	24.279	Down-regulation
AGC_RSK_RSKp70_RPS6KB1_ST	P27708	CAD	P23443	RPS6KB1	S1978	R1975L	1975	Missense	distal	-3	no	26.434	16.767	EPSD	COSMIC	24.279	Loss
AGC_RSK_RSKp70_RPS6KB1_ST	P27708	CAD	P23443	RPS6KB1	S2089	G2084R	2084	Missense	distal	-5	no	23.794	31.038	EPSD	COSMIC	24.279	Gain
AGC_RSK_RSKp70_RPS6KB1_ST	P27708	CAD	P23443	RPS6KB1	S2154	R2151L	2151	Missense	distal	-3	no	32.412	22.745	EPSD	COSMIC	24.279	Loss
AGC_RSK_RSKp70_RPS6KB1_ST	P27708	CAD	P23443	RPS6KB1	S2154	A2160T	2160	Missense	distal	6	no	32.412	33.600	EPSD	COSMIC	24.279	Up-regulation
AGC_RSK_RSKp70_RPS6KB1_ST	Q09161	NCBP1	P23443	RPS6KB1	S7	D11G	11	Missense	distal	4	no	36.147	35.638	EPSD;PhosphoSitePlus	COSMIC;CCLE	24.279	Down-regulation
AGC_RSK_RSKp70_RPS6KB1_ST	Q09161	NCBP1	P23443	RPS6KB1	S434	P441H	441	Missense	distal	7	no	28.061	27.889	EPSD	COSMIC	24.279	Down-regulation
AGC_RSK_RSKp70_RPS6KB1_ST	Q9GZT9	EGLN1	P23443	RPS6KB1	T185	G183W	183	Missense	proximal	-2	no	32.445	34.228	EPSD	COSMIC	24.279	Up-regulation
AGC_RSK_RSKp70_RPS6KB1_ST	Q9GZT9	EGLN1	P23443	RPS6KB1	T296	K291R	291	Missense	distal	-5	no	18.941	24.733	EPSD	COSMIC	24.279	Gain
AGC_RSK_RSKp70_RPS6KB1_ST	P78371	CCT2	P23443	RPS6KB1	T99	G96R	96	Missense	distal	-3	no	23.973	31.797	EPSD	COSMIC	24.279	Gain
AGC_RSK_RSKp70_RPS6KB1_ST	P78371	CCT2	P23443	RPS6KB1	S101	G96R	96	Missense	distal	-5	no	23.052	30.297	EPSD	COSMIC	24.279	Gain
AGC_RSK_RSKp70_RPS6KB1_ST	P78371	CCT2	P23443	RPS6KB1	S143	G149D	149	Missense	distal	6	no	31.119	29.637	EPSD	COSMIC	24.279	Down-regulation
AGC_RSK_RSKp70_RPS6KB1_ST	P78371	CCT2	P23443	RPS6KB1	S143	S150C	150	Missense	distal	7	no	31.119	29.585	EPSD	COSMIC;GDSC;CCLE	24.279	Down-regulation
AGC_RSK_RSKp70_RPS6KB1_ST	P78371	CCT2	P23443	RPS6KB1	S143	A136T	136	Missense	distal	-7	no	31.119	31.026	EPSD	COSMIC	24.279	Down-regulation
AGC_RSK_RSKp70_RPS6KB1_ST	O60331	PIP5K1C	P23443	RPS6KB1	T69	E68K	68	Missense	proximal	-1	no	26.322	26.386	EPSD	COSMIC	24.279	Up-regulation
AGC_RSK_RSKp70_RPS6KB1_ST	O60331	PIP5K1C	P23443	RPS6KB1	T69	A65T	65	Missense	distal	-4	no	26.322	26.552	EPSD	COSMIC	24.279	Up-regulation
AGC_RSK_RSKp70_RPS6KB1_ST	O60331	PIP5K1C	P23443	RPS6KB1	T69	S66F	66	Missense	distal	-3	no	26.322	22.652	EPSD	COSMIC	24.279	Loss
AGC_RSK_RSKp70_RPS6KB1_ST	O60331	PIP5K1C	P23443	RPS6KB1	S228	L223M	223	Missense	distal	-5	no	20.030	25.287	EPSD	COSMIC;GDSC;CCLE	24.279	Gain
AGC_RSK_RSKp70_RPS6KB1_ST	O60331	PIP5K1C	P23443	RPS6KB1	S448	T442M	442	Missense	distal	-6	no	33.501	33.512	EPSD	COSMIC;CCLE	24.279	Up-regulation
AGC_RSK_RSKp70_RPS6KB1_ST	O60331	PIP5K1C	P23443	RPS6KB1	S448	S448F	448	Missense	central	0	yes	33.501	0.000	EPSD	COSMIC	24.279	Loss
AGC_RSK_RSKp70_RPS6KB1_ST	O60331	PIP5K1C	P23443	RPS6KB1	S449	T442M	442	Missense	distal	-7	no	25.884	25.860	EPSD	COSMIC;CCLE	24.279	Down-regulation
AGC_RSK_RSKp70_RPS6KB1_ST	O60331	PIP5K1C	P23443	RPS6KB1	S449	S448F	448	Missense	proximal	-1	no	25.884	26.003	EPSD	COSMIC	24.279	Up-regulation
AGC_RSK_RSKp70_RPS6KB1_ST	O60331	PIP5K1C	P23443	RPS6KB1	S453	G460S	460	Missense	distal	7	no	36.855	37.233	EPSD	COSMIC	24.279	Up-regulation
AGC_RSK_RSKp70_RPS6KB1_ST	O60331	PIP5K1C	P23443	RPS6KB1	S453	G460C	460	Missense	distal	7	no	36.855	35.698	EPSD	COSMIC	24.279	Down-regulation
AGC_RSK_RSKp70_RPS6KB1_ST	O60331	PIP5K1C	P23443	RPS6KB1	S453	S448F	448	Missense	distal	-5	no	36.855	31.084	EPSD	COSMIC	24.279	Down-regulation
AGC_RSK_RSKp70_RPS6KB1_ST	O60331	PIP5K1C	P23443	RPS6KB1	S476	P481S	481	Missense	distal	5	no	22.823	24.758	EPSD	COSMIC	24.279	Gain
AGC_RSK_RSKp70_RPS6KB1_ST	O60331	PIP5K1C	P23443	RPS6KB1	S496	R495H	495	Missense	proximal	-1	no	27.598	27.615	EPSD	COSMIC	24.279	Up-regulation
AGC_RSK_RSKp70_RPS6KB1_ST	O60331	PIP5K1C	P23443	RPS6KB1	S496	E501Q	501	Missense	distal	5	no	27.598	27.752	EPSD	COSMIC	24.279	Up-regulation
AGC_RSK_RSKp70_RPS6KB1_ST	O60331	PIP5K1C	P23443	RPS6KB1	S496	D490N	490	Missense	distal	-6	no	27.598	27.561	EPSD	COSMIC	24.279	Down-regulation
AGC_RSK_RSKp70_RPS6KB1_ST	O60331	PIP5K1C	P23443	RPS6KB1	S496	L500V	500	Missense	distal	4	no	27.598	26.832	EPSD	COSMIC;GDSC;CCLE	24.279	Down-regulation
AGC_RSK_RSKp70_RPS6KB1_ST	O60331	PIP5K1C	P23443	RPS6KB1	S523	E517K	517	Missense	distal	-6	no	26.853	26.845	EPSD	COSMIC	24.279	Down-regulation
AGC_RSK_RSKp70_RPS6KB1_ST	O60331	PIP5K1C	P23443	RPS6KB1	S541	R538L	538	Missense	distal	-3	no	24.868	15.201	EPSD	COSMIC	24.279	Loss
AGC_RSK_RSKp70_RPS6KB1_ST	O60331	PIP5K1C	P23443	RPS6KB1	T553	R552G	552	Missense	proximal	-1	no	35.564	35.620	EPSD;PhosphoSitePlus	COSMIC	24.279	Up-regulation
AGC_RSK_RSKp70_RPS6KB1_ST	O60331	PIP5K1C	P23443	RPS6KB1	T553	R552C	552	Missense	proximal	-1	no	35.564	35.637	EPSD;PhosphoSitePlus	COSMIC;GDSC;CCLE	24.279	Up-regulation
AGC_RSK_RSKp70_RPS6KB1_ST	O60331	PIP5K1C	P23443	RPS6KB1	T553	R552L	552	Missense	proximal	-1	no	35.564	35.584	EPSD;PhosphoSitePlus	COSMIC	24.279	Up-regulation
AGC_RSK_RSKp70_RPS6KB1_ST	O60331	PIP5K1C	P23443	RPS6KB1	S555	R552G	552	Missense	distal	-3	no	37.679	29.855	PhosphoSitePlus;EPSD	COSMIC	24.279	Down-regulation
AGC_RSK_RSKp70_RPS6KB1_ST	O60331	PIP5K1C	P23443	RPS6KB1	S555	R552C	552	Missense	distal	-3	no	37.679	28.130	PhosphoSitePlus;EPSD	COSMIC;GDSC;CCLE	24.279	Down-regulation
AGC_RSK_RSKp70_RPS6KB1_ST	O60331	PIP5K1C	P23443	RPS6KB1	S555	R552L	552	Missense	distal	-3	no	37.679	28.012	PhosphoSitePlus;EPSD	COSMIC	24.279	Down-regulation
AGC_RSK_RSKp70_RPS6KB1_ST	P08151	GLI1	P23443	RPS6KB1	S69	P66R	66	Missense	distal	-3	no	16.613	29.234	EPSD	COSMIC	24.279	Gain
AGC_RSK_RSKp70_RPS6KB1_ST	P08151	GLI1	P23443	RPS6KB1	S84	S84F	84	Missense	central	0	yes	37.289	0.000	PhosphoSitePlus	COSMIC	24.279	Loss
AGC_RSK_RSKp70_RPS6KB1_ST	P08151	GLI1	P23443	RPS6KB1	S84	L88M	88	Missense	distal	4	no	37.289	37.040	PhosphoSitePlus	COSMIC	24.279	Down-regulation
AGC_RSK_RSKp70_RPS6KB1_ST	P08151	GLI1	P23443	RPS6KB1	S86	S84F	84	Missense	proximal	-2	no	27.111	28.978	EPSD	COSMIC	24.279	Up-regulation
AGC_RSK_RSKp70_RPS6KB1_ST	P08151	GLI1	P23443	RPS6KB1	S86	S92N	92	Missense	distal	6	no	27.111	25.655	EPSD	COSMIC	24.279	Down-regulation
AGC_RSK_RSKp70_RPS6KB1_ST	P08151	GLI1	P23443	RPS6KB1	S86	L88M	88	Missense	proximal	2	no	27.111	26.540	EPSD	COSMIC	24.279	Down-regulation
AGC_RSK_RSKp70_RPS6KB1_ST	P08151	GLI1	P23443	RPS6KB1	S243	D240G	240	Missense	distal	-3	no	21.197	24.826	EPSD	COSMIC	24.279	Gain
AGC_RSK_RSKp70_RPS6KB1_ST	P08151	GLI1	P23443	RPS6KB1	T296	R293H	293	Missense	distal	-3	no	25.630	22.142	EPSD	COSMIC	24.279	Loss
AGC_RSK_RSKp70_RPS6KB1_ST	P08151	GLI1	P23443	RPS6KB1	T296	E298V	298	Missense	proximal	2	no	25.630	24.743	EPSD	COSMIC	24.279	Down-regulation
AGC_RSK_RSKp70_RPS6KB1_ST	P08151	GLI1	P23443	RPS6KB1	T296	R293C	293	Missense	distal	-3	no	25.630	16.081	EPSD	COSMIC	24.279	Loss
AGC_RSK_RSKp70_RPS6KB1_ST	P08151	GLI1	P23443	RPS6KB1	T304	G307W	307	Missense	distal	3	no	26.205	27.005	EPSD	COSMIC	24.279	Up-regulation
AGC_RSK_RSKp70_RPS6KB1_ST	P08151	GLI1	P23443	RPS6KB1	T304	E306K	306	Missense	proximal	2	no	26.205	27.863	EPSD	COSMIC	24.279	Up-regulation
AGC_RSK_RSKp70_RPS6KB1_ST	P08151	GLI1	P23443	RPS6KB1	T304	E298V	298	Missense	distal	-6	no	26.205	26.262	EPSD	COSMIC	24.279	Up-regulation
AGC_RSK_RSKp70_RPS6KB1_ST	P08151	GLI1	P23443	RPS6KB1	T304	G307E	307	Missense	distal	3	no	26.205	30.433	EPSD	COSMIC	24.279	Up-regulation
AGC_RSK_RSKp70_RPS6KB1_ST	P08151	GLI1	P23443	RPS6KB1	S408	S410C	410	Missense	proximal	2	no	30.573	27.788	EPSD	COSMIC	24.279	Down-regulation
AGC_RSK_RSKp70_RPS6KB1_ST	P08151	GLI1	P23443	RPS6KB1	S408	P407S	407	Missense	proximal	-1	no	30.573	30.477	EPSD	COSMIC	24.279	Down-regulation
AGC_RSK_RSKp70_RPS6KB1_ST	P08151	GLI1	P23443	RPS6KB1	S408	S408P	408	Missense	central	0	yes	30.573	0.000	EPSD	COSMIC	24.279	Loss
AGC_RSK_RSKp70_RPS6KB1_ST	P08151	GLI1	P23443	RPS6KB1	S408	P414S	414	Missense	distal	6	no	30.573	31.548	EPSD	COSMIC	24.279	Up-regulation
AGC_RSK_RSKp70_RPS6KB1_ST	P08151	GLI1	P23443	RPS6KB1	S408	R405Q	405	Missense	distal	-3	no	30.573	11.518	EPSD	COSMIC	24.279	Loss
AGC_RSK_RSKp70_RPS6KB1_ST	P08151	GLI1	P23443	RPS6KB1	S408	P414L	414	Missense	distal	6	no	30.573	31.393	EPSD	COSMIC	24.279	Up-regulation
AGC_RSK_RSKp70_RPS6KB1_ST	P08151	GLI1	P23443	RPS6KB1	S408	K415Q	415	Missense	distal	7	no	30.573	30.840	EPSD	COSMIC	24.279	Up-regulation
AGC_RSK_RSKp70_RPS6KB1_ST	P08151	GLI1	P23443	RPS6KB1	S521	T514I	514	Missense	distal	-7	no	28.561	28.687	EPSD	COSMIC	24.279	Up-regulation
AGC_RSK_RSKp70_RPS6KB1_ST	P08151	GLI1	P23443	RPS6KB1	S521	G516S	516	Missense	distal	-5	no	28.561	30.266	EPSD	COSMIC	24.279	Up-regulation
AGC_RSK_RSKp70_RPS6KB1_ST	P08151	GLI1	P23443	RPS6KB1	S521	T525N	525	Missense	distal	4	no	28.561	28.241	EPSD	COSMIC	24.279	Down-regulation
AGC_RSK_RSKp70_RPS6KB1_ST	P08151	GLI1	P23443	RPS6KB1	S521	T525I	525	Missense	distal	4	no	28.561	28.122	EPSD	COSMIC	24.279	Down-regulation
AGC_RSK_RSKp70_RPS6KB1_ST	P08151	GLI1	P23443	RPS6KB1	S544	S538C	538	Missense	distal	-6	no	26.742	26.788	EPSD	COSMIC	24.279	Up-regulation
AGC_RSK_RSKp70_RPS6KB1_ST	P08151	GLI1	P23443	RPS6KB1	S544	R541C	541	Missense	distal	-3	no	26.742	17.193	EPSD	COSMIC;GDSC;CCLE	24.279	Loss
AGC_RSK_RSKp70_RPS6KB1_ST	P08151	GLI1	P23443	RPS6KB1	S544	S550G	550	Missense	distal	6	no	26.742	26.907	EPSD	COSMIC	24.279	Up-regulation
AGC_RSK_RSKp70_RPS6KB1_ST	P08151	GLI1	P23443	RPS6KB1	S544	S548N	548	Missense	distal	4	no	26.742	25.672	EPSD	COSMIC	24.279	Down-regulation
AGC_RSK_RSKp70_RPS6KB1_ST	P08151	GLI1	P23443	RPS6KB1	S545	S538C	538	Missense	distal	-7	no	26.328	26.492	EPSD	COSMIC	24.279	Up-regulation
AGC_RSK_RSKp70_RPS6KB1_ST	P08151	GLI1	P23443	RPS6KB1	S545	R541C	541	Missense	distal	-4	no	26.328	24.935	EPSD	COSMIC;GDSC;CCLE	24.279	Down-regulation
AGC_RSK_RSKp70_RPS6KB1_ST	P08151	GLI1	P23443	RPS6KB1	S545	S550G	550	Missense	distal	5	no	26.328	25.192	EPSD	COSMIC	24.279	Down-regulation
AGC_RSK_RSKp70_RPS6KB1_ST	P08151	GLI1	P23443	RPS6KB1	S545	S548N	548	Missense	distal	3	no	26.328	25.490	EPSD	COSMIC	24.279	Down-regulation
AGC_RSK_RSKp70_RPS6KB1_ST	P08151	GLI1	P23443	RPS6KB1	S602	A605S	605	Missense	distal	3	no	24.229	26.678	EPSD	COSMIC	24.279	Gain
AGC_RSK_RSKp70_RPS6KB1_ST	P08151	GLI1	P23443	RPS6KB1	S602	G598E	598	Missense	distal	-4	no	24.229	25.772	EPSD	COSMIC	24.279	Gain
AGC_RSK_RSKp70_RPS6KB1_ST	P08151	GLI1	P23443	RPS6KB1	S602	G599R	599	Missense	distal	-3	no	24.229	32.053	EPSD	COSMIC	24.279	Gain
AGC_RSK_RSKp70_RPS6KB1_ST	P08151	GLI1	P23443	RPS6KB1	S934	R940Q	940	Missense	distal	6	no	26.629	26.443	EPSD	COSMIC	24.279	Down-regulation
AGC_RSK_RSKp70_RPS6KB1_ST	P08151	GLI1	P23443	RPS6KB1	S934	R940W	940	Missense	distal	6	no	26.629	25.987	EPSD	COSMIC	24.279	Down-regulation
AGC_RSK_RSKp70_RPS6KB1_ST	P08151	GLI1	P23443	RPS6KB1	S934	L931R	931	Missense	distal	-3	no	26.629	36.296	EPSD	COSMIC	24.279	Up-regulation
AGC_RSK_RSKp70_RPS6KB1_ST	P08151	GLI1	P23443	RPS6KB1	S934	G933D	933	Missense	proximal	-1	no	26.629	26.649	EPSD	COSMIC	24.279	Up-regulation
AGC_RSK_RSKp70_RPS6KB1_ST	P08151	GLI1	P23443	RPS6KB1	S934	G932E	932	Missense	proximal	-2	no	26.629	28.137	EPSD	COSMIC;CCLE	24.279	Up-regulation
AGC_RSK_RSKp70_RPS6KB1_ST	P08151	GLI1	P23443	RPS6KB1	S934	R940C	940	Missense	distal	6	no	26.629	26.202	EPSD	COSMIC	24.279	Down-regulation
AGC_RSK_RSKp70_RPS6KB1_ST	P08151	GLI1	P23443	RPS6KB1	S934	K929T	929	Missense	distal	-5	no	26.629	24.815	EPSD	COSMIC	24.279	Down-regulation
AGC_RSK_RSKp70_RPS6KB1_ST	P08151	GLI1	P23443	RPS6KB1	S934	P928L	928	Missense	distal	-6	no	26.629	26.621	EPSD	COSMIC	24.279	Down-regulation
AGC_RSK_RSKp70_RPS6KB1_ST	P08151	GLI1	P23443	RPS6KB1	S934	S934F	934	Missense	central	0	yes	26.629	0.000	EPSD	COSMIC	24.279	Loss
AGC_RSK_RSKp70_RPS6KB1_ST	P08151	GLI1	P23443	RPS6KB1	S934	A941T	941	Missense	distal	7	no	26.629	26.277	EPSD	COSMIC	24.279	Down-regulation
AGC_RSK_RSKp70_RPS6KB1_ST	Q6R327	RICTOR	P23443	RPS6KB1	S21	E23D	23	Missense	proximal	2	no	34.352	33.666	EPSD	COSMIC;GDSC;CCLE	24.279	Down-regulation
AGC_RSK_RSKp70_RPS6KB1_ST	Q6R327	RICTOR	P23443	RPS6KB1	S21	P27S	27	Missense	distal	6	no	34.352	35.327	EPSD	COSMIC	24.279	Up-regulation
AGC_RSK_RSKp70_RPS6KB1_ST	Q6R327	RICTOR	P23443	RPS6KB1	S21	R14Q	14	Missense	distal	-7	no	34.352	34.422	EPSD	COSMIC	24.279	Up-regulation
AGC_RSK_RSKp70_RPS6KB1_ST	Q6R327	RICTOR	P23443	RPS6KB1	S21	G17E	17	Missense	distal	-4	no	34.352	35.895	EPSD	COSMIC	24.279	Up-regulation
AGC_RSK_RSKp70_RPS6KB1_ST	Q6R327	RICTOR	P23443	RPS6KB1	S35	E40D	40	Missense	distal	5	no	31.100	29.931	EPSD	COSMIC	24.279	Down-regulation
AGC_RSK_RSKp70_RPS6KB1_ST	Q6R327	RICTOR	P23443	RPS6KB1	S35	D29E	29	Missense	distal	-6	no	31.100	31.055	EPSD	COSMIC	24.279	Down-regulation
AGC_RSK_RSKp70_RPS6KB1_ST	Q6R327	RICTOR	P23443	RPS6KB1	S383	P378L	378	Missense	distal	-5	no	27.362	27.216	EPSD	COSMIC	24.279	Down-regulation
AGC_RSK_RSKp70_RPS6KB1_ST	Q6R327	RICTOR	P23443	RPS6KB1	S383	R384G	384	Missense	proximal	1	no	27.362	27.674	EPSD	COSMIC	24.279	Up-regulation
AGC_RSK_RSKp70_RPS6KB1_ST	Q6R327	RICTOR	P23443	RPS6KB1	S383	R380L	380	Missense	distal	-3	no	27.362	17.695	EPSD	COSMIC	24.279	Loss
AGC_RSK_RSKp70_RPS6KB1_ST	Q6R327	RICTOR	P23443	RPS6KB1	S383	L377I	377	Missense	distal	-6	no	27.362	27.380	EPSD	COSMIC	24.279	Up-regulation
AGC_RSK_RSKp70_RPS6KB1_ST	Q6R327	RICTOR	P23443	RPS6KB1	S383	H379Y	379	Missense	distal	-4	no	27.362	27.852	EPSD	COSMIC	24.279	Up-regulation
AGC_RSK_RSKp70_RPS6KB1_ST	Q6R327	RICTOR	P23443	RPS6KB1	T701	L698V	698	Missense	distal	-3	no	27.589	22.503	EPSD	COSMIC	24.279	Loss
AGC_RSK_RSKp70_RPS6KB1_ST	Q6R327	RICTOR	P23443	RPS6KB1	T701	S703F	703	Missense	proximal	2	no	27.589	22.391	EPSD	COSMIC	24.279	Loss
AGC_RSK_RSKp70_RPS6KB1_ST	Q6R327	RICTOR	P23443	RPS6KB1	T701	S704G	704	Missense	distal	3	no	27.589	23.595	EPSD	COSMIC	24.279	Loss
AGC_RSK_RSKp70_RPS6KB1_ST	Q6R327	RICTOR	P23443	RPS6KB1	S704	L698V	698	Missense	distal	-6	no	30.862	30.895	EPSD	COSMIC	24.279	Up-regulation
AGC_RSK_RSKp70_RPS6KB1_ST	Q6R327	RICTOR	P23443	RPS6KB1	S704	G711E	711	Missense	distal	7	no	30.862	30.996	EPSD	COSMIC	24.279	Up-regulation
AGC_RSK_RSKp70_RPS6KB1_ST	Q6R327	RICTOR	P23443	RPS6KB1	S704	S703F	703	Missense	proximal	-1	no	30.862	30.982	EPSD	COSMIC	24.279	Up-regulation
AGC_RSK_RSKp70_RPS6KB1_ST	Q6R327	RICTOR	P23443	RPS6KB1	S704	S704G	704	Missense	central	0	yes	30.862	0.000	EPSD	COSMIC	24.279	Loss
AGC_RSK_RSKp70_RPS6KB1_ST	Q6R327	RICTOR	P23443	RPS6KB1	S810	S816F	816	Missense	distal	6	no	25.425	23.411	EPSD	COSMIC	24.279	Loss
AGC_RSK_RSKp70_RPS6KB1_ST	Q6R327	RICTOR	P23443	RPS6KB1	S810	L804V	804	Missense	distal	-6	no	25.425	25.458	EPSD	COSMIC	24.279	Up-regulation
AGC_RSK_RSKp70_RPS6KB1_ST	Q6R327	RICTOR	P23443	RPS6KB1	S1026	T1029A	1029	Missense	distal	3	no	29.112	28.509	EPSD	COSMIC	24.279	Down-regulation
AGC_RSK_RSKp70_RPS6KB1_ST	Q6R327	RICTOR	P23443	RPS6KB1	S1028	T1029A	1029	Missense	proximal	1	no	25.996	24.879	EPSD	COSMIC	24.279	Down-regulation
AGC_RSK_RSKp70_RPS6KB1_ST	Q6R327	RICTOR	P23443	RPS6KB1	S1035	P1041S	1041	Missense	distal	6	no	29.070	30.045	EPSD	COSMIC;GDSC;CCLE	24.279	Up-regulation
AGC_RSK_RSKp70_RPS6KB1_ST	Q6R327	RICTOR	P23443	RPS6KB1	S1035	T1029A	1029	Missense	distal	-6	no	29.070	29.087	EPSD	COSMIC	24.279	Up-regulation
AGC_RSK_RSKp70_RPS6KB1_ST	Q6R327	RICTOR	P23443	RPS6KB1	S1037	P1041S	1041	Missense	distal	4	no	31.384	32.318	EPSD	COSMIC;GDSC;CCLE	24.279	Up-regulation
AGC_RSK_RSKp70_RPS6KB1_ST	Q6R327	RICTOR	P23443	RPS6KB1	S1122	P1115A	1115	Missense	distal	-7	no	26.492	26.428	EPSD	COSMIC	24.279	Down-regulation
AGC_RSK_RSKp70_RPS6KB1_ST	Q6R327	RICTOR	P23443	RPS6KB1	T1133	D1140E	1140	Missense	distal	7	no	38.698	39.552	EPSD	COSMIC	24.279	Up-regulation
AGC_RSK_RSKp70_RPS6KB1_ST	Q6R327	RICTOR	P23443	RPS6KB1	T1133	T1135A	1135	Missense	proximal	2	no	38.698	36.734	EPSD	COSMIC	24.279	Down-regulation
AGC_RSK_RSKp70_RPS6KB1_ST	Q6R327	RICTOR	P23443	RPS6KB1	T1133	D1140Y	1140	Missense	distal	7	no	38.698	39.098	EPSD	COSMIC	24.279	Up-regulation
AGC_RSK_RSKp70_RPS6KB1_ST	Q6R327	RICTOR	P23443	RPS6KB1	T1135	D1140E	1140	Missense	distal	5	no	40.784	41.954	PhosphoSitePlus	COSMIC	24.279	Up-regulation
AGC_RSK_RSKp70_RPS6KB1_ST	Q6R327	RICTOR	P23443	RPS6KB1	T1135	T1135A	1135	Missense	central	0	yes	40.784	0.000	PhosphoSitePlus	COSMIC	24.279	Loss
AGC_RSK_RSKp70_RPS6KB1_ST	Q6R327	RICTOR	P23443	RPS6KB1	T1135	D1140Y	1140	Missense	distal	5	no	40.784	39.379	PhosphoSitePlus	COSMIC	24.279	Down-regulation
AGC_RSK_RSKp70_RPS6KB1_ST	Q6R327	RICTOR	P23443	RPS6KB1	S1211	K1214Q	1214	Missense	distal	3	no	30.296	27.942	EPSD	COSMIC	24.279	Down-regulation
AGC_RSK_RSKp70_RPS6KB1_ST	Q6R327	RICTOR	P23443	RPS6KB1	S1211	M1213L	1213	Missense	proximal	2	no	30.296	30.867	EPSD	COSMIC	24.279	Up-regulation
AGC_RSK_RSKp70_RPS6KB1_ST	Q6R327	RICTOR	P23443	RPS6KB1	S1211	Q1218P	1218	Missense	distal	7	no	30.296	29.773	EPSD	COSMIC	24.279	Down-regulation
AGC_RSK_RSKp70_RPS6KB1_ST	Q6R327	RICTOR	P23443	RPS6KB1	S1211	S1211L	1211	Missense	central	0	yes	30.296	0.000	EPSD	COSMIC	24.279	Loss
AGC_RSK_RSKp70_RPS6KB1_ST	Q6R327	RICTOR	P23443	RPS6KB1	S1219	K1214Q	1214	Missense	distal	-5	no	36.673	30.490	EPSD	COSMIC	24.279	Down-regulation
AGC_RSK_RSKp70_RPS6KB1_ST	Q6R327	RICTOR	P23443	RPS6KB1	S1219	M1213L	1213	Missense	distal	-6	no	36.673	36.685	EPSD	COSMIC	24.279	Up-regulation
AGC_RSK_RSKp70_RPS6KB1_ST	Q6R327	RICTOR	P23443	RPS6KB1	S1219	Q1218P	1218	Missense	proximal	-1	no	36.673	36.712	EPSD	COSMIC	24.279	Up-regulation
AGC_RSK_RSKp70_RPS6KB1_ST	Q6R327	RICTOR	P23443	RPS6KB1	S1231	P1236A	1236	Missense	distal	5	no	24.578	24.785	EPSD	COSMIC	24.279	Up-regulation
AGC_RSK_RSKp70_RPS6KB1_ST	Q6R327	RICTOR	P23443	RPS6KB1	S1235	P1236A	1236	Missense	proximal	1	no	29.045	27.647	EPSD	COSMIC	24.279	Down-regulation
AGC_RSK_RSKp70_RPS6KB1_ST	Q6R327	RICTOR	P23443	RPS6KB1	S1235	E1239D	1239	Missense	distal	4	no	29.045	29.138	EPSD	COSMIC	24.279	Up-regulation
AGC_RSK_RSKp70_RPS6KB1_ST	Q6R327	RICTOR	P23443	RPS6KB1	S1237	P1236A	1236	Missense	proximal	-1	no	26.803	26.811	EPSD	COSMIC	24.279	Up-regulation
AGC_RSK_RSKp70_RPS6KB1_ST	Q6R327	RICTOR	P23443	RPS6KB1	S1237	E1239D	1239	Missense	proximal	2	no	26.803	26.117	EPSD	COSMIC	24.279	Down-regulation
AGC_RSK_RSKp70_RPS6KB1_ST	Q6R327	RICTOR	P23443	RPS6KB1	S1274	L1279P	1279	Missense	distal	5	no	24.836	23.611	EPSD	COSMIC;CCLE	24.279	Loss
AGC_RSK_RSKp70_RPS6KB1_ST	Q6R327	RICTOR	P23443	RPS6KB1	S1274	S1278F	1278	Missense	distal	4	no	24.836	22.675	EPSD	COSMIC	24.279	Loss
AGC_RSK_RSKp70_RPS6KB1_ST	Q6R327	RICTOR	P23443	RPS6KB1	S1278	N1283S	1283	Missense	distal	5	no	23.543	26.581	EPSD	COSMIC	24.279	Gain
AGC_RSK_RSKp70_RPS6KB1_ST	Q6R327	RICTOR	P23443	RPS6KB1	S1302	A1309V	1309	Missense	distal	7	no	29.044	28.440	EPSD	COSMIC	24.279	Down-regulation
AGC_RSK_RSKp70_RPS6KB1_ST	Q6R327	RICTOR	P23443	RPS6KB1	S1302	P1297S	1297	Missense	distal	-5	no	29.044	31.983	EPSD	COSMIC	24.279	Up-regulation
AGC_RSK_RSKp70_RPS6KB1_ST	Q6R327	RICTOR	P23443	RPS6KB1	S1302	R1299K	1299	Missense	distal	-3	no	29.044	21.425	EPSD	COSMIC	24.279	Loss
AGC_RSK_RSKp70_RPS6KB1_ST	Q6R327	RICTOR	P23443	RPS6KB1	S1307	A1309V	1309	Missense	proximal	2	no	24.384	23.548	EPSD	COSMIC	24.279	Loss
AGC_RSK_RSKp70_RPS6KB1_ST	Q6R327	RICTOR	P23443	RPS6KB1	S1344	R1340I	1340	Missense	distal	-4	no	33.629	33.825	EPSD	COSMIC	24.279	Up-regulation
AGC_RSK_RSKp70_RPS6KB1_ST	Q6R327	RICTOR	P23443	RPS6KB1	S1344	M1341L	1341	Missense	distal	-3	no	33.629	29.461	EPSD	COSMIC	24.279	Down-regulation
AGC_RSK_RSKp70_RPS6KB1_ST	Q6R327	RICTOR	P23443	RPS6KB1	S1346	R1340I	1340	Missense	distal	-6	no	26.466	26.521	EPSD	COSMIC	24.279	Up-regulation
AGC_RSK_RSKp70_RPS6KB1_ST	Q6R327	RICTOR	P23443	RPS6KB1	S1346	M1341L	1341	Missense	distal	-5	no	26.466	21.209	EPSD	COSMIC	24.279	Loss
AGC_RSK_RSKp70_RPS6KB1_ST	Q6R327	RICTOR	P23443	RPS6KB1	S1348	M1341L	1341	Missense	distal	-7	no	28.252	28.369	EPSD	COSMIC	24.279	Up-regulation
AGC_RSK_RSKp70_RPS6KB1_ST	Q6R327	RICTOR	P23443	RPS6KB1	S1348	P1354L	1354	Missense	distal	6	no	28.252	29.071	EPSD	COSMIC	24.279	Up-regulation
AGC_RSK_RSKp70_RPS6KB1_ST	Q6R327	RICTOR	P23443	RPS6KB1	S1385	R1379K	1379	Missense	distal	-6	no	26.309	26.313	EPSD	COSMIC	24.279	Up-regulation
AGC_RSK_RSKp70_RPS6KB1_ST	Q6R327	RICTOR	P23443	RPS6KB1	S1385	R1379S	1379	Missense	distal	-6	no	26.309	26.303	EPSD	COSMIC	24.279	Down-regulation
AGC_RSK_RSKp70_RPS6KB1_ST	Q6R327	RICTOR	P23443	RPS6KB1	S1385	L1384S	1384	Missense	proximal	-1	no	26.309	26.260	EPSD	COSMIC;GDSC;CCLE	24.279	Down-regulation
AGC_RSK_RSKp70_RPS6KB1_ST	Q6R327	RICTOR	P23443	RPS6KB1	S1385	F1380L	1380	Missense	distal	-5	no	26.309	28.996	EPSD	COSMIC	24.279	Up-regulation
AGC_RSK_RSKp70_RPS6KB1_ST	Q6R327	RICTOR	P23443	RPS6KB1	S1415	R1410W	1410	Missense	distal	-5	no	34.047	22.083	EPSD	COSMIC	24.279	Loss
AGC_RSK_RSKp70_RPS6KB1_ST	Q6R327	RICTOR	P23443	RPS6KB1	S1415	G1420S	1420	Missense	distal	5	no	34.047	35.184	EPSD	COSMIC	24.279	Up-regulation
AGC_RSK_RSKp70_RPS6KB1_ST	Q6R327	RICTOR	P23443	RPS6KB1	S1415	S1421L	1421	Missense	distal	6	no	34.047	33.892	EPSD	COSMIC	24.279	Down-regulation
AGC_RSK_RSKp70_RPS6KB1_ST	Q6R327	RICTOR	P23443	RPS6KB1	S1415	R1410Q	1410	Missense	distal	-5	no	34.047	22.072	EPSD	COSMIC	24.279	Loss
AGC_RSK_RSKp70_RPS6KB1_ST	Q6R327	RICTOR	P23443	RPS6KB1	S1588	S1581F	1581	Missense	distal	-7	no	28.571	28.932	EPSD	COSMIC	24.279	Up-regulation
AGC_RSK_RSKp70_RPS6KB1_ST	Q6R327	RICTOR	P23443	RPS6KB1	S1588	S1591N	1591	Missense	distal	3	no	28.571	27.732	EPSD	COSMIC	24.279	Down-regulation
AGC_RSK_RSKp70_RPS6KB1_ST	P78362	SRPK2	P23443	RPS6KB1	S380	P375R	375	Missense	distal	-5	no	20.087	28.566	EPSD	COSMIC	24.279	Gain
AGC_RSK_RSKp70_RPS6KB1_ST	P78362	SRPK2	P23443	RPS6KB1	S469	E463Q	463	Missense	distal	-6	no	24.274	24.297	EPSD	COSMIC	24.279	Gain
AGC_RSK_RSKp70_RPS6KB1_ST	P78362	SRPK2	P23443	RPS6KB1	S475	L471I	471	Missense	distal	-4	no	28.695	28.587	EPSD	COSMIC	24.279	Down-regulation
AGC_RSK_RSKp70_RPS6KB1_ST	P78362	SRPK2	P23443	RPS6KB1	S490	S497R	497	Missense	distal	7	no	30.252	29.718	EPSD	COSMIC	24.279	Down-regulation
AGC_RSK_RSKp70_RPS6KB1_ST	P78362	SRPK2	P23443	RPS6KB1	T492	T498A	498	Missense	distal	6	no	25.320	24.132	EPSD	COSMIC	24.279	Loss
AGC_RSK_RSKp70_RPS6KB1_ST	P78362	SRPK2	P23443	RPS6KB1	T492	S497R	497	Missense	distal	5	no	25.320	23.423	EPSD	COSMIC	24.279	Loss
AGC_RSK_RSKp70_RPS6KB1_ST	P78362	SRPK2	P23443	RPS6KB1	S494	T498A	498	Missense	distal	4	no	31.477	31.723	PhosphoSitePlus	COSMIC	24.279	Up-regulation
AGC_RSK_RSKp70_RPS6KB1_ST	P78362	SRPK2	P23443	RPS6KB1	S494	S497R	497	Missense	distal	3	no	31.477	29.909	PhosphoSitePlus	COSMIC	24.279	Down-regulation
AGC_RSK_RSKp70_RPS6KB1_ST	P78362	SRPK2	P23443	RPS6KB1	S496	T498A	498	Missense	proximal	2	no	29.049	27.085	EPSD	COSMIC	24.279	Down-regulation
AGC_RSK_RSKp70_RPS6KB1_ST	P78362	SRPK2	P23443	RPS6KB1	S496	S497R	497	Missense	proximal	1	no	29.049	29.839	EPSD	COSMIC	24.279	Up-regulation
AGC_RSK_RSKp70_RPS6KB1_ST	P23588	EIF4B	P23443	RPS6KB1	T14	F20L	20	Missense	distal	6	no	24.119	25.979	EPSD	COSMIC	24.279	Gain
AGC_RSK_RSKp70_RPS6KB1_ST	P23588	EIF4B	P23443	RPS6KB1	T14	K11R	11	Missense	distal	-3	no	24.119	31.739	EPSD	COSMIC	24.279	Gain
AGC_RSK_RSKp70_RPS6KB1_ST	P23588	EIF4B	P23443	RPS6KB1	S16	F20L	20	Missense	distal	4	no	25.102	26.816	EPSD	COSMIC	24.279	Up-regulation
AGC_RSK_RSKp70_RPS6KB1_ST	P23588	EIF4B	P23443	RPS6KB1	S16	D19Y	19	Missense	distal	3	no	25.102	24.783	EPSD	COSMIC	24.279	Down-regulation
AGC_RSK_RSKp70_RPS6KB1_ST	P23588	EIF4B	P23443	RPS6KB1	S16	K11R	11	Missense	distal	-5	no	25.102	30.895	EPSD	COSMIC	24.279	Up-regulation
AGC_RSK_RSKp70_RPS6KB1_ST	P23588	EIF4B	P23443	RPS6KB1	S35	V38I	38	Missense	distal	3	no	30.297	30.553	EPSD	COSMIC	24.279	Up-regulation
AGC_RSK_RSKp70_RPS6KB1_ST	P23588	EIF4B	P23443	RPS6KB1	S93	R87Q	87	Missense	distal	-6	no	28.236	28.271	EPSD	COSMIC;GDSC;CCLE	24.279	Up-regulation
AGC_RSK_RSKp70_RPS6KB1_ST	P23588	EIF4B	P23443	RPS6KB1	T205	P212Q	212	Missense	distal	7	no	33.776	34.299	EPSD	COSMIC	24.279	Up-regulation
AGC_RSK_RSKp70_RPS6KB1_ST	P23588	EIF4B	P23443	RPS6KB1	T205	P203R	203	Missense	proximal	-2	no	33.776	32.515	EPSD	COSMIC	24.279	Down-regulation
AGC_RSK_RSKp70_RPS6KB1_ST	P23588	EIF4B	P23443	RPS6KB1	T205	R202S	202	Missense	distal	-3	no	33.776	24.292	EPSD	COSMIC	24.279	Down-regulation
AGC_RSK_RSKp70_RPS6KB1_ST	P23588	EIF4B	P23443	RPS6KB1	T205	W199R	199	Missense	distal	-6	no	33.776	33.713	EPSD	COSMIC;GDSC;CCLE	24.279	Down-regulation
AGC_RSK_RSKp70_RPS6KB1_ST	P23588	EIF4B	P23443	RPS6KB1	S207	P212Q	212	Missense	distal	5	no	25.808	26.507	EPSD	COSMIC	24.279	Up-regulation
AGC_RSK_RSKp70_RPS6KB1_ST	P23588	EIF4B	P23443	RPS6KB1	S207	P203R	203	Missense	distal	-4	no	25.808	26.416	EPSD	COSMIC	24.279	Up-regulation
AGC_RSK_RSKp70_RPS6KB1_ST	P23588	EIF4B	P23443	RPS6KB1	S207	R202S	202	Missense	distal	-5	no	25.808	20.269	EPSD	COSMIC	24.279	Loss
AGC_RSK_RSKp70_RPS6KB1_ST	P23588	EIF4B	P23443	RPS6KB1	S219	P212Q	212	Missense	distal	-7	no	25.633	25.534	EPSD	COSMIC	24.279	Down-regulation
AGC_RSK_RSKp70_RPS6KB1_ST	P23588	EIF4B	P23443	RPS6KB1	S230	Y237H	237	Missense	distal	7	no	30.025	30.077	EPSD	COSMIC	24.279	Up-regulation
AGC_RSK_RSKp70_RPS6KB1_ST	P23588	EIF4B	P23443	RPS6KB1	S230	R232Q	232	Missense	proximal	2	no	30.025	28.218	EPSD	COSMIC	24.279	Down-regulation
AGC_RSK_RSKp70_RPS6KB1_ST	P23588	EIF4B	P23443	RPS6KB1	S230	R232W	232	Missense	proximal	2	no	30.025	27.333	EPSD	COSMIC	24.279	Down-regulation
AGC_RSK_RSKp70_RPS6KB1_ST	P23588	EIF4B	P23443	RPS6KB1	S276	R273W	273	Missense	distal	-3	no	26.212	11.197	EPSD	COSMIC	24.279	Loss
AGC_RSK_RSKp70_RPS6KB1_ST	P23588	EIF4B	P23443	RPS6KB1	S276	I274T	274	Missense	proximal	-2	no	26.212	26.200	EPSD	COSMIC;GDSC;CCLE	24.279	Down-regulation
AGC_RSK_RSKp70_RPS6KB1_ST	P23588	EIF4B	P23443	RPS6KB1	S283	R287M	287	Missense	distal	4	no	24.121	24.626	EPSD	COSMIC	24.279	Gain
AGC_RSK_RSKp70_RPS6KB1_ST	P23588	EIF4B	P23443	RPS6KB1	S309	S309L	309	Missense	central	0	yes	24.979	0.000	EPSD	COSMIC	24.279	Loss
AGC_RSK_RSKp70_RPS6KB1_ST	P23588	EIF4B	P23443	RPS6KB1	S309	R308W	308	Missense	proximal	-1	no	24.979	25.032	EPSD	COSMIC	24.279	Up-regulation
AGC_RSK_RSKp70_RPS6KB1_ST	P23588	EIF4B	P23443	RPS6KB1	S309	Y316C	316	Missense	distal	7	no	24.979	24.143	EPSD	COSMIC	24.279	Loss
AGC_RSK_RSKp70_RPS6KB1_ST	P23588	EIF4B	P23443	RPS6KB1	S309	R305W	305	Missense	distal	-4	no	24.979	23.299	EPSD	COSMIC	24.279	Loss
AGC_RSK_RSKp70_RPS6KB1_ST	P23588	EIF4B	P23443	RPS6KB1	S309	R304K	304	Missense	distal	-5	no	24.979	19.187	EPSD	COSMIC	24.279	Loss
AGC_RSK_RSKp70_RPS6KB1_ST	P23588	EIF4B	P23443	RPS6KB1	S311	S309L	309	Missense	proximal	-2	no	28.465	28.606	EPSD	COSMIC	24.279	Up-regulation
AGC_RSK_RSKp70_RPS6KB1_ST	P23588	EIF4B	P23443	RPS6KB1	S311	R308W	308	Missense	distal	-3	no	28.465	13.449	EPSD	COSMIC	24.279	Loss
AGC_RSK_RSKp70_RPS6KB1_ST	P23588	EIF4B	P23443	RPS6KB1	S311	Y316C	316	Missense	distal	5	no	28.465	29.032	EPSD	COSMIC	24.279	Up-regulation
AGC_RSK_RSKp70_RPS6KB1_ST	P23588	EIF4B	P23443	RPS6KB1	S311	R305W	305	Missense	distal	-6	no	28.465	28.528	EPSD	COSMIC	24.279	Up-regulation
AGC_RSK_RSKp70_RPS6KB1_ST	P23588	EIF4B	P23443	RPS6KB1	S311	R304K	304	Missense	distal	-7	no	28.465	28.476	EPSD	COSMIC	24.279	Up-regulation
AGC_RSK_RSKp70_RPS6KB1_ST	P23588	EIF4B	P23443	RPS6KB1	S352	S347P	347	Missense	distal	-5	no	28.095	25.156	EPSD	COSMIC	24.279	Down-regulation
AGC_RSK_RSKp70_RPS6KB1_ST	P23588	EIF4B	P23443	RPS6KB1	S352	R356L	356	Missense	distal	4	no	28.095	28.849	EPSD	COSMIC	24.279	Up-regulation
AGC_RSK_RSKp70_RPS6KB1_ST	P23588	EIF4B	P23443	RPS6KB1	S406	E402K	402	Missense	distal	-4	no	26.685	28.077	EPSD	COSMIC	24.279	Up-regulation
AGC_RSK_RSKp70_RPS6KB1_ST	P23588	EIF4B	P23443	RPS6KB1	T420	R419K	419	Missense	proximal	-1	no	30.157	30.197	EPSD	COSMIC	24.279	Up-regulation
AGC_RSK_RSKp70_RPS6KB1_ST	P23588	EIF4B	P23443	RPS6KB1	T420	S418T	418	Missense	proximal	-2	no	30.157	31.207	EPSD	COSMIC	24.279	Up-regulation
AGC_RSK_RSKp70_RPS6KB1_ST	P23588	EIF4B	P23443	RPS6KB1	T420	R417Q	417	Missense	distal	-3	no	30.157	11.101	EPSD	COSMIC	24.279	Loss
AGC_RSK_RSKp70_RPS6KB1_ST	P23588	EIF4B	P23443	RPS6KB1	S422	R419K	419	Missense	distal	-3	no	44.185	36.566	PhosphoSitePlus	COSMIC	24.279	Down-regulation
AGC_RSK_RSKp70_RPS6KB1_ST	P23588	EIF4B	P23443	RPS6KB1	S422	S418T	418	Missense	distal	-4	no	44.185	43.293	PhosphoSitePlus	COSMIC	24.279	Down-regulation
AGC_RSK_RSKp70_RPS6KB1_ST	P23588	EIF4B	P23443	RPS6KB1	S422	R417Q	417	Missense	distal	-5	no	44.185	32.210	PhosphoSitePlus	COSMIC	24.279	Down-regulation
AGC_RSK_RSKp70_RPS6KB1_ST	P23588	EIF4B	P23443	RPS6KB1	S422	G428E	428	Missense	distal	6	no	44.185	43.320	PhosphoSitePlus	COSMIC;GDSC;CCLE	24.279	Down-regulation
AGC_RSK_RSKp70_RPS6KB1_ST	P23588	EIF4B	P23443	RPS6KB1	S430	G428E	428	Missense	proximal	-2	no	27.290	28.798	EPSD	COSMIC;GDSC;CCLE	24.279	Up-regulation
AGC_RSK_RSKp70_RPS6KB1_ST	P23588	EIF4B	P23443	RPS6KB1	S433	G428E	428	Missense	distal	-5	no	23.695	26.340	EPSD	COSMIC;GDSC;CCLE	24.279	Gain
AGC_RSK_RSKp70_RPS6KB1_ST	P23588	EIF4B	P23443	RPS6KB1	S434	E441K	441	Missense	distal	7	no	27.843	27.871	EPSD	COSMIC	24.279	Up-regulation
AGC_RSK_RSKp70_RPS6KB1_ST	P23588	EIF4B	P23443	RPS6KB1	S434	G428E	428	Missense	distal	-6	no	27.843	27.826	EPSD	COSMIC;GDSC;CCLE	24.279	Down-regulation
AGC_RSK_RSKp70_RPS6KB1_ST	P23588	EIF4B	P23443	RPS6KB1	S442	E441K	441	Missense	proximal	-1	no	27.234	27.298	EPSD	COSMIC	24.279	Up-regulation
AGC_RSK_RSKp70_RPS6KB1_ST	P23588	EIF4B	P23443	RPS6KB1	S445	E441K	441	Missense	distal	-4	no	25.144	26.535	EPSD	COSMIC	24.279	Up-regulation
AGC_RSK_RSKp70_RPS6KB1_ST	P23588	EIF4B	P23443	RPS6KB1	S459	P464T	464	Missense	distal	5	no	26.806	27.856	EPSD	COSMIC	24.279	Up-regulation
AGC_RSK_RSKp70_RPS6KB1_ST	P23588	EIF4B	P23443	RPS6KB1	S459	P465A	465	Missense	distal	6	no	26.806	26.661	EPSD	COSMIC	24.279	Down-regulation
AGC_RSK_RSKp70_RPS6KB1_ST	P23588	EIF4B	P23443	RPS6KB1	T461	P464T	464	Missense	distal	3	no	28.065	28.759	EPSD	COSMIC	24.279	Up-regulation
AGC_RSK_RSKp70_RPS6KB1_ST	P23588	EIF4B	P23443	RPS6KB1	T461	P465A	465	Missense	distal	4	no	28.065	28.495	EPSD	COSMIC	24.279	Up-regulation
AGC_RSK_RSKp70_RPS6KB1_ST	P23588	EIF4B	P23443	RPS6KB1	S498	S504I	504	Missense	distal	6	no	26.499	25.375	EPSD	COSMIC	24.279	Down-regulation
AGC_RSK_RSKp70_RPS6KB1_ST	P23588	EIF4B	P23443	RPS6KB1	S504	S504I	504	Missense	central	0	yes	26.035	0.000	EPSD	COSMIC	24.279	Loss
AGC_RSK_RSKp70_RPS6KB1_ST	P23588	EIF4B	P23443	RPS6KB1	S504	S507I	507	Missense	distal	3	no	26.035	24.225	EPSD	COSMIC	24.279	Loss
AGC_RSK_RSKp70_RPS6KB1_ST	Q9BY77	POLDIP3	P23443	RPS6KB1	S215	S216N	216	Missense	proximal	1	no	30.893	30.426	EPSD	COSMIC	24.279	Down-regulation
AGC_RSK_RSKp70_RPS6KB1_ST	Q9BY77	POLDIP3	P23443	RPS6KB1	S215	M211T	211	Missense	distal	-4	no	30.893	30.092	EPSD	COSMIC	24.279	Down-regulation
AGC_RSK_RSKp70_RPS6KB1_ST	Q9BY77	POLDIP3	P23443	RPS6KB1	S215	A212V	212	Missense	distal	-3	no	30.893	26.061	EPSD	COSMIC	24.279	Down-regulation
AGC_RSK_RSKp70_RPS6KB1_ST	Q9BY77	POLDIP3	P23443	RPS6KB1	S216	S216N	216	Missense	central	0	yes	25.437	0.000	EPSD	COSMIC	24.279	Loss
AGC_RSK_RSKp70_RPS6KB1_ST	Q9BY77	POLDIP3	P23443	RPS6KB1	S216	M211T	211	Missense	distal	-5	no	25.437	21.198	EPSD	COSMIC	24.279	Loss
AGC_RSK_RSKp70_RPS6KB1_ST	Q9BY77	POLDIP3	P23443	RPS6KB1	S216	A212V	212	Missense	distal	-4	no	25.437	24.449	EPSD	COSMIC	24.279	Down-regulation
AGC_RSK_RSKp70_RPS6KB1_ST	Q9BY77	POLDIP3	P23443	RPS6KB1	S254	R255W	255	Missense	proximal	1	no	29.605	30.081	EPSD	COSMIC	24.279	Up-regulation
AGC_RSK_RSKp70_RPS6KB1_ST	Q9BY77	POLDIP3	P23443	RPS6KB1	S254	M253V	253	Missense	proximal	-1	no	29.605	29.616	EPSD	COSMIC	24.279	Up-regulation
AGC_RSK_RSKp70_RPS6KB1_ST	Q9BY77	POLDIP3	P23443	RPS6KB1	S254	T256A	256	Missense	proximal	2	no	29.605	27.640	EPSD	COSMIC;GDSC;CCLE	24.279	Down-regulation
AGC_RSK_RSKp70_RPS6KB1_ST	Q9BY77	POLDIP3	P23443	RPS6KB1	S383	P390H	390	Missense	distal	7	no	35.954	35.781	PhosphoSitePlus;EPSD	COSMIC	24.279	Down-regulation
AGC_RSK_RSKp70_RPS6KB1_ST	Q9BY77	POLDIP3	P23443	RPS6KB1	S383	R379H	379	Missense	distal	-4	no	35.954	35.498	PhosphoSitePlus;EPSD	COSMIC	24.279	Down-regulation
AGC_RSK_RSKp70_RPS6KB1_ST	Q9BY77	POLDIP3	P23443	RPS6KB1	S383	S383Y	383	Missense	central	0	yes	35.954	0.000	PhosphoSitePlus;EPSD	COSMIC	24.279	Loss
AGC_RSK_RSKp70_RPS6KB1_ST	Q9BY77	POLDIP3	P23443	RPS6KB1	S383	A384S	384	Missense	proximal	1	no	35.954	36.334	PhosphoSitePlus;EPSD	COSMIC;GDSC;CCLE	24.279	Up-regulation
AGC_RSK_RSKp70_RPS6KB1_ST	Q9BY77	POLDIP3	P23443	RPS6KB1	S385	P390H	390	Missense	distal	5	no	35.699	36.038	EPSD;PhosphoSitePlus	COSMIC	24.279	Up-regulation
AGC_RSK_RSKp70_RPS6KB1_ST	Q9BY77	POLDIP3	P23443	RPS6KB1	S385	R379H	379	Missense	distal	-6	no	35.699	35.713	EPSD;PhosphoSitePlus	COSMIC	24.279	Up-regulation
AGC_RSK_RSKp70_RPS6KB1_ST	Q9BY77	POLDIP3	P23443	RPS6KB1	S385	S383Y	383	Missense	proximal	-2	no	35.699	36.642	EPSD;PhosphoSitePlus	COSMIC	24.279	Up-regulation
AGC_RSK_RSKp70_RPS6KB1_ST	Q9BY77	POLDIP3	P23443	RPS6KB1	S385	A384S	384	Missense	proximal	-1	no	35.699	35.595	EPSD;PhosphoSitePlus	COSMIC;GDSC;CCLE	24.279	Down-regulation
AGC_RSK_RSKp70_RPS6KB1_ST	Q9BY77	POLDIP3	P23443	RPS6KB1	S409	P414L	414	Missense	distal	5	no	23.124	24.349	EPSD	COSMIC;GDSC;CCLE	24.279	Gain
Atypical_Alpha_ChaK_TRPM7_ST	Q96QT4	TRPM7	Q96QT4	TRPM7	T89	K82M	82	Missense	distal	-7	no	3.909	3.838	EPSD	COSMIC	3.661	Down-regulation
Atypical_Alpha_ChaK_TRPM7_ST	Q96QT4	TRPM7	Q96QT4	TRPM7	T1163	L1170F	1170	Missense	distal	7	no	3.565	3.744	EPSD;PhosphoSitePlus	COSMIC	3.661	Gain
Atypical_Alpha_ChaK_TRPM7_ST	Q96QT4	TRPM7	Q96QT4	TRPM7	T1163	P1158S	1158	Missense	distal	-5	no	3.565	3.966	EPSD;PhosphoSitePlus	COSMIC	3.661	Gain
Atypical_Alpha_ChaK_TRPM7_ST	Q96QT4	TRPM7	Q96QT4	TRPM7	S1191	F1189S	1189	Missense	proximal	-2	no	4.075	3.520	EPSD;PhosphoSitePlus	COSMIC	3.661	Loss
Atypical_Alpha_ChaK_TRPM7_ST	Q96QT4	TRPM7	Q96QT4	TRPM7	S1193	F1189S	1189	Missense	distal	-4	no	3.735	3.353	PhosphoSitePlus;EPSD	COSMIC	3.661	Loss
Atypical_Alpha_ChaK_TRPM7_ST	Q96QT4	TRPM7	Q96QT4	TRPM7	S1258	E1263Q	1263	Missense	distal	5	no	4.222	4.231	EPSD;PhosphoSitePlus	COSMIC	3.661	Up-regulation
Atypical_Alpha_ChaK_TRPM7_ST	Q96QT4	TRPM7	Q96QT4	TRPM7	S1287	G1293D	1293	Missense	distal	6	no	3.847	3.964	EPSD;PhosphoSitePlus	COSMIC	3.661	Up-regulation
Atypical_Alpha_ChaK_TRPM7_ST	Q96QT4	TRPM7	Q96QT4	TRPM7	S1358	P1362S	1362	Missense	distal	4	no	5.135	5.258	EPSD;PhosphoSitePlus	COSMIC;GDSC	3.661	Up-regulation
Atypical_Alpha_ChaK_TRPM7_ST	Q96QT4	TRPM7	Q96QT4	TRPM7	S1387	G1385C	1385	Missense	proximal	-2	no	4.463	4.410	EPSD;PhosphoSitePlus	COSMIC	3.661	Down-regulation
Atypical_Alpha_ChaK_TRPM7_ST	Q96QT4	TRPM7	Q96QT4	TRPM7	S1390	G1385C	1385	Missense	distal	-5	no	4.119	4.151	EPSD;PhosphoSitePlus	COSMIC	3.661	Up-regulation
Atypical_Alpha_ChaK_TRPM7_ST	Q96QT4	TRPM7	Q96QT4	TRPM7	T1405	P1406S	1406	Missense	proximal	1	no	3.832	4.057	EPSD;PhosphoSitePlus	COSMIC	3.661	Up-regulation
Atypical_Alpha_ChaK_TRPM7_ST	Q96QT4	TRPM7	Q96QT4	TRPM7	T1405	F1401C	1401	Missense	distal	-4	no	3.832	3.855	EPSD;PhosphoSitePlus	COSMIC;CCLE	3.661	Up-regulation
Atypical_Alpha_ChaK_TRPM7_ST	Q96QT4	TRPM7	Q96QT4	TRPM7	T1435	A1429G	1429	Missense	distal	-6	no	4.560	4.707	EPSD;PhosphoSitePlus	COSMIC	3.661	Up-regulation
Atypical_Alpha_ChaK_TRPM7_ST	Q96QT4	TRPM7	Q96QT4	TRPM7	S1446	S1446I	1446	Missense	central	0	yes	4.149	0.000	EPSD;PhosphoSitePlus	COSMIC	3.661	Loss
Atypical_Alpha_ChaK_TRPM7_ST	Q96QT4	TRPM7	Q96QT4	TRPM7	S1446	D1445N	1445	Missense	proximal	-1	no	4.149	3.908	EPSD;PhosphoSitePlus	COSMIC	3.661	Down-regulation
Atypical_Alpha_ChaK_TRPM7_ST	Q96QT4	TRPM7	Q96QT4	TRPM7	S1476	A1479S	1479	Missense	distal	3	no	3.667	3.708	EPSD;PhosphoSitePlus	COSMIC	3.661	Up-regulation
Atypical_Alpha_ChaK_TRPM7_ST	Q96QT4	TRPM7	Q96QT4	TRPM7	S1493	A1496P	1496	Missense	distal	3	no	4.135	4.005	EPSD;PhosphoSitePlus	COSMIC	3.661	Down-regulation
Atypical_Alpha_ChaK_TRPM7_ST	Q96QT4	TRPM7	Q96QT4	TRPM7	T1505	E1506K	1506	Missense	proximal	1	no	4.082	4.023	EPSD;PhosphoSitePlus	COSMIC	3.661	Down-regulation
Atypical_Alpha_ChaK_TRPM7_ST	Q96QT4	TRPM7	Q96QT4	TRPM7	T1505	P1503S	1503	Missense	proximal	-2	no	4.082	3.675	EPSD;PhosphoSitePlus	COSMIC	3.661	Down-regulation
Atypical_Alpha_ChaK_TRPM7_ST	Q96QT4	TRPM7	Q96QT4	TRPM7	T1508	E1506K	1506	Missense	proximal	-2	no	3.934	4.074	EPSD;PhosphoSitePlus	COSMIC	3.661	Up-regulation
Atypical_Alpha_ChaK_TRPM7_ST	Q96QT4	TRPM7	Q96QT4	TRPM7	T1508	P1503S	1503	Missense	distal	-5	no	3.934	4.334	EPSD;PhosphoSitePlus	COSMIC	3.661	Up-regulation
Atypical_Alpha_ChaK_TRPM7_ST	Q96QT4	TRPM7	Q96QT4	TRPM7	S1513	P1519L	1519	Missense	distal	6	no	4.711	4.674	EPSD;PhosphoSitePlus	COSMIC	3.661	Down-regulation
Atypical_Alpha_ChaK_TRPM7_ST	Q96QT4	TRPM7	Q96QT4	TRPM7	S1513	E1506K	1506	Missense	distal	-7	no	4.711	4.632	EPSD;PhosphoSitePlus	COSMIC	3.661	Down-regulation
Atypical_Alpha_ChaK_TRPM7_ST	Q96QT4	TRPM7	Q96QT4	TRPM7	S1533	E1530G	1530	Missense	distal	-3	no	3.637	3.760	EPSD;PhosphoSitePlus	COSMIC	3.661	Gain
Atypical_Alpha_ChaK_TRPM7_ST	Q96QT4	TRPM7	Q96QT4	TRPM7	T1551	V1558A	1558	Missense	distal	7	no	4.951	4.802	EPSD;PhosphoSitePlus	COSMIC	3.661	Down-regulation
Atypical_Alpha_ChaK_TRPM7_ST	Q96QT4	TRPM7	Q96QT4	TRPM7	T1551	V1558M	1558	Missense	distal	7	no	4.951	4.860	EPSD;PhosphoSitePlus	COSMIC	3.661	Down-regulation
Atypical_Alpha_ChaK_TRPM7_ST	Q96QT4	TRPM7	Q96QT4	TRPM7	T1551	M1549V	1549	Missense	proximal	-2	no	4.951	4.862	EPSD;PhosphoSitePlus	COSMIC	3.661	Down-regulation
Atypical_Alpha_ChaK_TRPM7_ST	Q96QT4	TRPM7	Q96QT4	TRPM7	T1551	D1550N	1550	Missense	proximal	-1	no	4.951	4.710	EPSD;PhosphoSitePlus	COSMIC	3.661	Down-regulation
Atypical_Alpha_ChaK_TRPM7_ST	Q96QT4	TRPM7	Q96QT4	TRPM7	S1569	L1566S	1566	Missense	distal	-3	no	4.881	4.778	EPSD;PhosphoSitePlus	COSMIC	3.661	Down-regulation
Atypical_Alpha_ChaK_TRPM7_ST	Q96QT4	TRPM7	Q96QT4	TRPM7	T1583	S1590L	1590	Missense	distal	7	no	2.979	3.708	EPSD;PhosphoSitePlus	COSMIC	3.661	Gain
Atypical_Alpha_ChaK_TRPM7_ST	Q96QT4	TRPM7	Q96QT4	TRPM7	S1598	S1591L	1591	Missense	distal	-7	no	4.441	4.267	EPSD;PhosphoSitePlus	COSMIC	3.661	Down-regulation
Atypical_Alpha_ChaK_TRPM7_ST	Q96QT4	TRPM7	Q96QT4	TRPM7	S1598	S1600F	1600	Missense	proximal	2	no	4.441	4.637	EPSD;PhosphoSitePlus	COSMIC	3.661	Up-regulation
Atypical_Alpha_ChaK_TRPM7_ST	Q96QT4	TRPM7	Q96QT4	TRPM7	S1660	S1659N	1659	Missense	proximal	-1	no	3.883	4.158	EPSD;PhosphoSitePlus	COSMIC	3.661	Up-regulation
Atypical_Alpha_ChaK_TRPM7_ST	Q96QT4	TRPM7	Q96QT4	TRPM7	S1660	S1660N	1660	Missense	central	0	yes	3.883	0.000	EPSD;PhosphoSitePlus	COSMIC	3.661	Loss
Atypical_Alpha_ChaK_TRPM7_ST	Q96QT4	TRPM7	Q96QT4	TRPM7	T1830	P1837H	1837	Missense	distal	7	no	4.250	3.660	EPSD;PhosphoSitePlus	COSMIC	3.661	Loss
Atypical_Alpha_ChaK_TRPM7_ST	Q96QT4	TRPM7	Q96QT4	TRPM7	T1830	D1832N	1832	Missense	proximal	2	no	4.250	4.279	EPSD;PhosphoSitePlus	COSMIC	3.661	Up-regulation
Atypical_Alpha_ChaK_TRPM7_ST	O00418	EEF2K	Q96QT4	TRPM7	T43	S47R	47	Missense	distal	4	no	3.765	3.727	EPSD	COSMIC	3.661	Down-regulation
Atypical_Alpha_ChaK_TRPM7_ST	O00418	EEF2K	Q96QT4	TRPM7	S47	S47R	47	Missense	central	0	yes	4.086	0.000	EPSD	COSMIC	3.661	Loss
Atypical_Alpha_ChaK_TRPM7_ST	O00418	EEF2K	Q96QT4	TRPM7	S345	L343P	343	Missense	proximal	-2	no	3.923	3.994	EPSD	COSMIC	3.661	Up-regulation
Atypical_Alpha_ChaK_TRPM7_ST	O00418	EEF2K	Q96QT4	TRPM7	S345	I349V	349	Missense	distal	4	no	3.923	3.886	EPSD	COSMIC	3.661	Down-regulation
Atypical_Alpha_ChaK_TRPM7_ST	O00418	EEF2K	Q96QT4	TRPM7	S366	T364N	364	Missense	proximal	-2	no	4.399	4.360	EPSD	COSMIC	3.661	Down-regulation
Atypical_Alpha_ChaK_TRPM7_ST	O00418	EEF2K	Q96QT4	TRPM7	S478	R480W	480	Missense	proximal	2	no	3.572	3.720	EPSD	COSMIC	3.661	Gain
Atypical_Alpha_ChaK_TRPM7_ST	O00418	EEF2K	Q96QT4	TRPM7	S622	S622Y	622	Missense	central	0	yes	3.713	0.000	EPSD	COSMIC	3.661	Loss
Atypical_Alpha_ChaK_TRPM7_ST	O00418	EEF2K	Q96QT4	TRPM7	S622	Q624L	624	Missense	proximal	2	no	3.713	3.814	EPSD	COSMIC	3.661	Up-regulation
Atypical_Alpha_ChaK_TRPM7_ST	O00418	EEF2K	Q96QT4	TRPM7	S622	A617T	617	Missense	distal	-5	no	3.713	3.801	EPSD	COSMIC	3.661	Up-regulation
Atypical_Alpha_ChaK_TRPM7_ST	P28289	TMOD1	Q96QT4	TRPM7	T54	P61R	61	Missense	distal	7	no	3.731	2.395	EPSD;PhosphoSitePlus	COSMIC	3.661	Loss
Atypical_Alpha_ChaK_TRPM7_ST	P28289	TMOD1	Q96QT4	TRPM7	T54	K56E	56	Missense	proximal	2	no	3.731	3.665	EPSD;PhosphoSitePlus	COSMIC	3.661	Down-regulation
Atypical_Alpha_ChaK_TRPM7_ST	P28289	TMOD1	Q96QT4	TRPM7	S281	A275V	275	Missense	distal	-6	no	4.083	4.091	EPSD	COSMIC	3.661	Up-regulation
Atypical_Alpha_ChaK_TRPM7_ST	P28289	TMOD1	Q96QT4	TRPM7	S281	N279S	279	Missense	proximal	-2	no	4.083	3.903	EPSD	COSMIC	3.661	Down-regulation
TK_Axl_MERTK_Y	Q12866	MERTK	Q12866	MERTK	Y749	K747R	747	Missense	proximal	-2	no	5.292	5.193	PhosphoSitePlus;EPSD	COSMIC	1.889	Down-regulation
TK_Axl_MERTK_Y	Q12866	MERTK	Q12866	MERTK	Y749	G751C	751	Missense	proximal	2	no	5.292	5.174	PhosphoSitePlus;EPSD	COSMIC	1.889	Down-regulation
TK_Axl_MERTK_Y	Q12866	MERTK	Q12866	MERTK	Y749	D752E	752	Missense	distal	3	no	5.292	5.278	PhosphoSitePlus;EPSD	COSMIC	1.889	Down-regulation
TK_Axl_MERTK_Y	Q12866	MERTK	Q12866	MERTK	Y753	K747R	747	Missense	distal	-6	no	6.115	6.035	EPSD;PhosphoSitePlus	COSMIC	1.889	Down-regulation
TK_Axl_MERTK_Y	Q12866	MERTK	Q12866	MERTK	Y753	G751C	751	Missense	proximal	-2	no	6.115	6.123	EPSD;PhosphoSitePlus	COSMIC	1.889	Up-regulation
TK_Axl_MERTK_Y	Q12866	MERTK	Q12866	MERTK	Y753	D752E	752	Missense	proximal	-1	no	6.115	5.764	EPSD;PhosphoSitePlus	COSMIC	1.889	Down-regulation
TK_Axl_MERTK_Y	Q12866	MERTK	Q12866	MERTK	Y754	K747R	747	Missense	distal	-7	no	5.341	5.181	EPSD;PhosphoSitePlus	COSMIC	1.889	Down-regulation
TK_Axl_MERTK_Y	Q12866	MERTK	Q12866	MERTK	Y754	G751C	751	Missense	distal	-3	no	5.341	5.268	EPSD;PhosphoSitePlus	COSMIC	1.889	Down-regulation
TK_Axl_MERTK_Y	Q12866	MERTK	Q12866	MERTK	Y754	D752E	752	Missense	proximal	-2	no	5.341	5.340	EPSD;PhosphoSitePlus	COSMIC	1.889	Down-regulation
TK_Axl_MERTK_Y	P42229	STAT5A	Q12866	MERTK	Y171	Q177K	177	Missense	distal	6	no	1.910	1.905	EPSD	COSMIC	1.889	Down-regulation
TK_Axl_MERTK_Y	P42229	STAT5A	Q12866	MERTK	Y171	Y171S	171	Missense	central	0	yes	1.910	0.000	EPSD	COSMIC	1.889	Loss
TK_Axl_MERTK_Y	P42229	STAT5A	Q12866	MERTK	Y694	A688D	688	Missense	distal	-6	no	6.349	6.570	PhosphoSitePlus	COSMIC	1.889	Up-regulation
TK_Axl_MERTK_Y	P51692	STAT5B	Q12866	MERTK	Y171	Q167H	167	Missense	distal	-4	no	2.073	2.082	EPSD	COSMIC	1.889	Up-regulation
TK_Axl_MERTK_Y	P51692	STAT5B	Q12866	MERTK	Y171	E178D	178	Missense	distal	7	no	2.073	1.779	EPSD	COSMIC	1.889	Loss
TK_Axl_MERTK_Y	P51692	STAT5B	Q12866	MERTK	Y171	Q175H	175	Missense	distal	4	no	2.073	1.979	EPSD	COSMIC	1.889	Down-regulation
TK_Axl_MERTK_Y	P51692	STAT5B	Q12866	MERTK	Y699	I704L	704	Missense	distal	5	no	5.619	5.667	PhosphoSitePlus	COSMIC	1.889	Up-regulation
TK_Axl_MERTK_Y	P51692	STAT5B	Q12866	MERTK	Y699	Q706L	706	Missense	distal	7	no	5.619	5.314	PhosphoSitePlus	COSMIC	1.889	Down-regulation
TK_Axl_MERTK_Y	P51692	STAT5B	Q12866	MERTK	Y699	K705N	705	Missense	distal	6	no	5.619	5.642	PhosphoSitePlus	COSMIC	1.889	Up-regulation
TK_Axl_MERTK_Y	P51692	STAT5B	Q12866	MERTK	Y699	G698E	698	Missense	proximal	-1	no	5.619	5.160	PhosphoSitePlus	COSMIC	1.889	Down-regulation
TK_Axl_MERTK_Y	P51692	STAT5B	Q12866	MERTK	Y699	V696L	696	Missense	distal	-3	no	5.619	5.560	PhosphoSitePlus	COSMIC	1.889	Down-regulation
TK_Axl_MERTK_Y	P40763	STAT3	Q12866	MERTK	Y686	G684R	684	Missense	proximal	-2	no	2.832	2.740	EPSD	COSMIC	1.889	Down-regulation
TK_Axl_MERTK_Y	P40763	STAT3	Q12866	MERTK	Y686	F683L	683	Missense	distal	-3	no	2.832	2.886	EPSD	COSMIC	1.889	Up-regulation
TK_Axl_MERTK_Y	P40763	STAT3	Q12866	MERTK	Y705	D698N	698	Missense	distal	-7	no	5.687	5.554	PhosphoSitePlus	COSMIC	1.889	Down-regulation
TK_Axl_MERTK_Y	P40763	STAT3	Q12866	MERTK	Y705	G700R	700	Missense	distal	-5	no	5.687	5.643	PhosphoSitePlus	COSMIC	1.889	Down-regulation
TK_Axl_MERTK_Y	P40763	STAT3	Q12866	MERTK	Y705	I711L	711	Missense	distal	6	no	5.687	5.720	PhosphoSitePlus	COSMIC	1.889	Up-regulation
STE_STE20_PAKB_PAK6_ST	Q00987	MDM2	Q9NQU5	PAK6	T158	P156R	156	Missense	proximal	-2	no	4.276	4.268	PhosphoSitePlus;EPSD	COSMIC	1.514	Down-regulation
STE_STE20_PAKB_PAK6_ST	Q00987	MDM2	Q9NQU5	PAK6	T158	R155T	155	Missense	distal	-3	no	4.276	4.298	PhosphoSitePlus;EPSD	COSMIC	1.514	Up-regulation
STE_STE20_PAKB_PAK6_ST	Q00987	MDM2	Q9NQU5	PAK6	T158	S160F	160	Missense	proximal	2	no	4.276	4.010	PhosphoSitePlus;EPSD	COSMIC	1.514	Down-regulation
STE_STE20_PAKB_PAK6_ST	Q00987	MDM2	Q9NQU5	PAK6	T158	H151Y	151	Missense	distal	-7	no	4.276	4.335	PhosphoSitePlus;EPSD	COSMIC	1.514	Up-regulation
STE_STE20_PAKB_PAK6_ST	Q00987	MDM2	Q9NQU5	PAK6	T158	P156S	156	Missense	proximal	-2	no	4.276	4.262	PhosphoSitePlus;EPSD	COSMIC	1.514	Down-regulation
STE_STE20_PAKB_PAK6_ST	Q00987	MDM2	Q9NQU5	PAK6	T158	S159R	159	Missense	proximal	1	no	4.276	4.367	PhosphoSitePlus;EPSD	COSMIC	1.514	Up-regulation
STE_STE20_PAKB_PAK6_ST	Q00987	MDM2	Q9NQU5	PAK6	T158	S159G	159	Missense	proximal	1	no	4.276	4.351	PhosphoSitePlus;EPSD	COSMIC	1.514	Up-regulation
STE_STE20_PAKB_PAK6_ST	Q00987	MDM2	Q9NQU5	PAK6	T158	S159N	159	Missense	proximal	1	no	4.276	4.319	PhosphoSitePlus;EPSD	COSMIC	1.514	Up-regulation
STE_STE20_PAKB_PAK6_ST	Q00987	MDM2	Q9NQU5	PAK6	T158	R161T	161	Missense	distal	3	no	4.276	4.157	PhosphoSitePlus;EPSD	COSMIC	1.514	Down-regulation
STE_STE20_PAKB_PAK6_ST	Q00987	MDM2	Q9NQU5	PAK6	S160	P156R	156	Missense	distal	-4	no	2.445	2.447	EPSD	COSMIC	1.514	Up-regulation
STE_STE20_PAKB_PAK6_ST	Q00987	MDM2	Q9NQU5	PAK6	S160	R155T	155	Missense	distal	-5	no	2.445	2.301	EPSD	COSMIC	1.514	Down-regulation
STE_STE20_PAKB_PAK6_ST	Q00987	MDM2	Q9NQU5	PAK6	S160	S160F	160	Missense	central	0	yes	2.445	0.000	EPSD	COSMIC	1.514	Loss
STE_STE20_PAKB_PAK6_ST	Q00987	MDM2	Q9NQU5	PAK6	S160	P156S	156	Missense	distal	-4	no	2.445	2.461	EPSD	COSMIC	1.514	Up-regulation
STE_STE20_PAKB_PAK6_ST	Q00987	MDM2	Q9NQU5	PAK6	S160	S159R	159	Missense	proximal	-1	no	2.445	2.463	EPSD	COSMIC	1.514	Up-regulation
STE_STE20_PAKB_PAK6_ST	Q00987	MDM2	Q9NQU5	PAK6	S160	S159G	159	Missense	proximal	-1	no	2.445	2.458	EPSD	COSMIC	1.514	Up-regulation
STE_STE20_PAKB_PAK6_ST	Q00987	MDM2	Q9NQU5	PAK6	S160	S166C	166	Missense	distal	6	no	2.445	2.467	EPSD	COSMIC	1.514	Up-regulation
STE_STE20_PAKB_PAK6_ST	Q00987	MDM2	Q9NQU5	PAK6	S160	E167Q	167	Missense	distal	7	no	2.445	2.484	EPSD	COSMIC	1.514	Up-regulation
STE_STE20_PAKB_PAK6_ST	Q00987	MDM2	Q9NQU5	PAK6	S160	S159N	159	Missense	proximal	-1	no	2.445	2.437	EPSD	COSMIC	1.514	Down-regulation
STE_STE20_PAKB_PAK6_ST	Q00987	MDM2	Q9NQU5	PAK6	S160	R161T	161	Missense	proximal	1	no	2.445	2.421	EPSD	COSMIC	1.514	Down-regulation
STE_STE20_PAKB_PAK6_ST	Q00987	MDM2	Q9NQU5	PAK6	S160	S166F	166	Missense	distal	6	no	2.445	2.459	EPSD	COSMIC	1.514	Up-regulation
STE_STE20_PAKB_PAK6_ST	Q00987	MDM2	Q9NQU5	PAK6	T168	E170D	170	Missense	proximal	2	no	1.769	1.914	EPSD	COSMIC	1.514	Up-regulation
STE_STE20_PAKB_PAK6_ST	Q00987	MDM2	Q9NQU5	PAK6	T168	D173Y	173	Missense	distal	5	no	1.769	1.488	EPSD	COSMIC	1.514	Loss
STE_STE20_PAKB_PAK6_ST	Q00987	MDM2	Q9NQU5	PAK6	T168	S166C	166	Missense	proximal	-2	no	1.769	1.798	EPSD	COSMIC	1.514	Up-regulation
STE_STE20_PAKB_PAK6_ST	Q00987	MDM2	Q9NQU5	PAK6	T168	E167Q	167	Missense	proximal	-1	no	1.769	1.807	EPSD	COSMIC	1.514	Up-regulation
STE_STE20_PAKB_PAK6_ST	Q00987	MDM2	Q9NQU5	PAK6	T168	R161T	161	Missense	distal	-7	no	1.769	1.749	EPSD	COSMIC	1.514	Down-regulation
STE_STE20_PAKB_PAK6_ST	Q00987	MDM2	Q9NQU5	PAK6	T168	S166F	166	Missense	proximal	-2	no	1.769	1.813	EPSD	COSMIC	1.514	Up-regulation
STE_STE20_PAKB_PAK6_ST	Q00987	MDM2	Q9NQU5	PAK6	S176	E170D	170	Missense	distal	-6	no	1.813	1.913	EPSD	COSMIC	1.514	Up-regulation
STE_STE20_PAKB_PAK6_ST	Q00987	MDM2	Q9NQU5	PAK6	S176	R183H	183	Missense	distal	7	no	1.813	1.713	EPSD	COSMIC	1.514	Down-regulation
STE_STE20_PAKB_PAK6_ST	Q00987	MDM2	Q9NQU5	PAK6	S176	E178K	178	Missense	proximal	2	no	1.813	1.922	EPSD	COSMIC	1.514	Up-regulation
STE_STE20_PAKB_PAK6_ST	Q00987	MDM2	Q9NQU5	PAK6	S176	S176F	176	Missense	central	0	yes	1.813	0.000	EPSD	COSMIC	1.514	Loss
STE_STE20_PAKB_PAK6_ST	Q00987	MDM2	Q9NQU5	PAK6	S176	G177D	177	Missense	proximal	1	no	1.813	1.765	EPSD	COSMIC	1.514	Down-regulation
STE_STE20_PAKB_PAK6_ST	Q00987	MDM2	Q9NQU5	PAK6	S176	R183C	183	Missense	distal	7	no	1.813	1.734	EPSD	COSMIC	1.514	Down-regulation
STE_STE20_PAKB_PAK6_ST	Q00987	MDM2	Q9NQU5	PAK6	S176	R179P	179	Missense	distal	3	no	1.813	1.620	EPSD	COSMIC	1.514	Down-regulation
STE_STE20_PAKB_PAK6_ST	Q00987	MDM2	Q9NQU5	PAK6	S176	D173Y	173	Missense	distal	-3	no	1.813	1.826	EPSD	COSMIC	1.514	Up-regulation
STE_STE20_PAKB_PAK6_ST	Q00987	MDM2	Q9NQU5	PAK6	S186	R183H	183	Missense	distal	-3	no	4.446	4.336	EPSD;PhosphoSitePlus	COSMIC	1.514	Down-regulation
STE_STE20_PAKB_PAK6_ST	Q00987	MDM2	Q9NQU5	PAK6	S186	I189V	189	Missense	distal	3	no	4.446	4.372	EPSD;PhosphoSitePlus	COSMIC	1.514	Down-regulation
STE_STE20_PAKB_PAK6_ST	Q00987	MDM2	Q9NQU5	PAK6	S186	K185R	185	Missense	proximal	-1	no	4.446	4.470	EPSD;PhosphoSitePlus	COSMIC	1.514	Up-regulation
STE_STE20_PAKB_PAK6_ST	Q00987	MDM2	Q9NQU5	PAK6	S186	S190F	190	Missense	distal	4	no	4.446	4.453	EPSD;PhosphoSitePlus	COSMIC	1.514	Up-regulation
STE_STE20_PAKB_PAK6_ST	Q00987	MDM2	Q9NQU5	PAK6	S186	R183C	183	Missense	distal	-3	no	4.446	4.169	EPSD;PhosphoSitePlus	COSMIC	1.514	Down-regulation
STE_STE20_PAKB_PAK6_ST	Q00987	MDM2	Q9NQU5	PAK6	S186	R179P	179	Missense	distal	-7	no	4.446	4.415	EPSD;PhosphoSitePlus	COSMIC	1.514	Down-regulation
STE_STE20_PAKB_PAK6_ST	Q00987	MDM2	Q9NQU5	PAK6	S220	N221I	221	Missense	proximal	1	no	2.175	2.185	EPSD	COSMIC	1.514	Up-regulation
STE_STE20_PAKB_PAK6_ST	Q00987	MDM2	Q9NQU5	PAK6	S220	D223H	223	Missense	distal	3	no	2.175	2.153	EPSD	COSMIC	1.514	Down-regulation
STE_STE20_PAKB_PAK6_ST	Q00987	MDM2	Q9NQU5	PAK6	S220	D223E	223	Missense	distal	3	no	2.175	2.210	EPSD	COSMIC	1.514	Up-regulation
STE_STE20_PAKB_PAK6_ST	Q00987	MDM2	Q9NQU5	PAK6	S220	T218M	218	Missense	proximal	-2	no	2.175	2.194	EPSD	COSMIC	1.514	Up-regulation
STE_STE20_PAKB_PAK6_ST	Q00987	MDM2	Q9NQU5	PAK6	S220	S220L	220	Missense	central	0	yes	2.175	0.000	EPSD	COSMIC	1.514	Loss
STE_STE20_PAKB_PAK6_ST	Q00987	MDM2	Q9NQU5	PAK6	S220	D223N	223	Missense	distal	3	no	2.175	2.165	EPSD	COSMIC	1.514	Down-regulation
STE_STE20_PAKB_PAK6_ST	Q00987	MDM2	Q9NQU5	PAK6	S220	D225N	225	Missense	distal	5	no	2.175	1.887	EPSD	COSMIC	1.514	Down-regulation
STE_STE20_PAKB_PAK6_ST	Q00987	MDM2	Q9NQU5	PAK6	S220	T216S	216	Missense	distal	-4	no	2.175	2.189	EPSD	COSMIC	1.514	Up-regulation
STE_STE20_PAKB_PAK6_ST	Q00987	MDM2	Q9NQU5	PAK6	S220	S220W	220	Missense	central	0	yes	2.175	0.000	EPSD	COSMIC	1.514	Loss
STE_STE20_PAKB_PAK6_ST	Q00987	MDM2	Q9NQU5	PAK6	S220	S215C	215	Missense	distal	-5	no	2.175	2.184	EPSD	COSMIC	1.514	Up-regulation
STE_STE20_PAKB_PAK6_ST	Q00987	MDM2	Q9NQU5	PAK6	S220	S213N	213	Missense	distal	-7	no	2.175	2.211	EPSD	COSMIC	1.514	Up-regulation
STE_STE20_PAKB_PAK6_ST	Q00987	MDM2	Q9NQU5	PAK6	S220	E214K	214	Missense	distal	-6	no	2.175	2.240	EPSD	COSMIC	1.514	Up-regulation
STE_STE20_PAKB_PAK6_ST	Q00987	MDM2	Q9NQU5	PAK6	S260	E257K	257	Missense	distal	-3	no	1.426	1.539	EPSD	COSMIC	1.514	Gain
STE_STE20_PAKB_PAK6_ST	Q00987	MDM2	Q9NQU5	PAK6	S260	D255N	255	Missense	distal	-5	no	1.426	1.561	EPSD	COSMIC	1.514	Gain
STE_STE20_PAKB_PAK6_ST	Q00987	MDM2	Q9NQU5	PAK6	T288	G284W	284	Missense	distal	-4	no	1.665	1.666	EPSD	COSMIC	1.514	Up-regulation
STE_STE20_PAKB_PAK6_ST	Q00987	MDM2	Q9NQU5	PAK6	T288	A283T	283	Missense	distal	-5	no	1.665	1.496	EPSD	COSMIC	1.514	Loss
STE_STE20_PAKB_PAK6_ST	Q00987	MDM2	Q9NQU5	PAK6	T288	Y281H	281	Missense	distal	-7	no	1.665	1.605	EPSD	COSMIC	1.514	Down-regulation
STE_STE20_PAKB_PAK6_ST	Q00987	MDM2	Q9NQU5	PAK6	T288	E285K	285	Missense	distal	-3	no	1.665	1.778	EPSD	COSMIC	1.514	Up-regulation
STE_STE20_PAKB_PAK6_ST	Q00987	MDM2	Q9NQU5	PAK6	T288	D294Y	294	Missense	distal	6	no	1.665	1.674	EPSD	COSMIC	1.514	Up-regulation
STE_STE20_PAKB_PAK6_ST	Q00987	MDM2	Q9NQU5	PAK6	T288	D287N	287	Missense	proximal	-1	no	1.665	1.669	EPSD	COSMIC	1.514	Up-regulation
STE_STE20_PAKB_PAK6_ST	Q00987	MDM2	Q9NQU5	PAK6	T288	F291S	291	Missense	distal	3	no	1.665	1.593	EPSD	COSMIC	1.514	Down-regulation
STE_STE20_PAKB_PAK6_ST	Q00987	MDM2	Q9NQU5	PAK6	T288	E292K	292	Missense	distal	4	no	1.665	1.642	EPSD	COSMIC	1.514	Down-regulation
STE_STE20_PAKB_PAK6_ST	Q00987	MDM2	Q9NQU5	PAK6	S395	D393E	393	Missense	proximal	-2	no	1.569	1.559	EPSD	COSMIC	1.514	Down-regulation
STE_STE20_PAKB_PAK6_ST	Q00987	MDM2	Q9NQU5	PAK6	S395	D393H	393	Missense	proximal	-2	no	1.569	1.556	EPSD	COSMIC	1.514	Down-regulation
STE_STE20_PAKB_PAK6_ST	Q00987	MDM2	Q9NQU5	PAK6	S425	T419I	419	Missense	distal	-6	no	1.528	1.721	EPSD	COSMIC	1.514	Up-regulation
STE_STE20_PAKB_PAK6_ST	Q00987	MDM2	Q9NQU5	PAK6	S425	S425C	425	Missense	central	0	yes	1.528	0.000	EPSD	COSMIC	1.514	Loss
STE_STE20_PAKB_PAK6_ST	Q00987	MDM2	Q9NQU5	PAK6	S425	S429R	429	Missense	distal	4	no	1.528	1.535	EPSD	COSMIC	1.514	Up-regulation
STE_STE20_PAKB_PAK6_ST	Q00987	MDM2	Q9NQU5	PAK6	S425	V426A	426	Missense	proximal	1	no	1.528	1.515	EPSD	COSMIC	1.514	Down-regulation
STE_STE20_PAKB_PAK6_ST	Q9BY11	PACSIN1	Q9NQU5	PAK6	T16	A11V	11	Missense	distal	-5	no	1.516	1.359	EPSD	COSMIC	1.514	Loss
STE_STE20_PAKB_PAK6_ST	Q9BY11	PACSIN1	Q9NQU5	PAK6	T16	D17N	17	Missense	proximal	1	no	1.516	1.533	EPSD	COSMIC	1.514	Up-regulation
STE_STE20_PAKB_PAK6_ST	Q9BY11	PACSIN1	Q9NQU5	PAK6	T28	I32V	32	Missense	distal	4	no	2.423	2.415	EPSD	COSMIC	1.514	Down-regulation
STE_STE20_PAKB_PAK6_ST	Q9BY11	PACSIN1	Q9NQU5	PAK6	S339	G345R	345	Missense	distal	6	no	1.782	1.734	EPSD	COSMIC	1.514	Down-regulation
STE_STE20_PAKB_PAK6_ST	Q9BY11	PACSIN1	Q9NQU5	PAK6	S339	T332N	332	Missense	distal	-7	no	1.782	1.756	EPSD	COSMIC	1.514	Down-regulation
STE_STE20_PAKB_PAK6_ST	Q9BY11	PACSIN1	Q9NQU5	PAK6	S339	R344C	344	Missense	distal	5	no	1.782	1.797	EPSD	COSMIC	1.514	Up-regulation
STE_STE20_PAKB_PAK6_ST	Q9BY11	PACSIN1	Q9NQU5	PAK6	S339	G333A	333	Missense	distal	-6	no	1.782	1.729	EPSD	COSMIC;GDSC;CCLE	1.514	Down-regulation
STE_STE20_PAKB_PAK6_ST	Q9BY11	PACSIN1	Q9NQU5	PAK6	S339	S339F	339	Missense	central	0	yes	1.782	0.000	EPSD	COSMIC;CCLE	1.514	Loss
STE_STE20_PAKB_PAK6_ST	Q9BY11	PACSIN1	Q9NQU5	PAK6	S339	V335L	335	Missense	distal	-4	no	1.782	1.785	EPSD	COSMIC;GDSC;CCLE	1.514	Up-regulation
STE_STE20_PAKB_PAK6_ST	Q9BY11	PACSIN1	Q9NQU5	PAK6	S339	A341S	341	Missense	proximal	2	no	1.782	2.121	EPSD	COSMIC	1.514	Up-regulation
STE_STE20_PAKB_PAK6_ST	Q9BY11	PACSIN1	Q9NQU5	PAK6	S339	G342E	342	Missense	distal	3	no	1.782	1.511	EPSD	COSMIC	1.514	Loss
STE_STE20_PAKB_PAK6_ST	Q9BY11	PACSIN1	Q9NQU5	PAK6	S346	G345R	345	Missense	proximal	-1	no	4.590	4.595	PhosphoSitePlus	COSMIC	1.514	Up-regulation
STE_STE20_PAKB_PAK6_ST	Q9BY11	PACSIN1	Q9NQU5	PAK6	S346	R344C	344	Missense	proximal	-2	no	4.590	4.614	PhosphoSitePlus	COSMIC	1.514	Up-regulation
STE_STE20_PAKB_PAK6_ST	Q9BY11	PACSIN1	Q9NQU5	PAK6	S346	D351V	351	Missense	distal	5	no	4.590	4.145	PhosphoSitePlus	COSMIC	1.514	Down-regulation
STE_STE20_PAKB_PAK6_ST	Q9BY11	PACSIN1	Q9NQU5	PAK6	S346	S339F	339	Missense	distal	-7	no	4.590	4.665	PhosphoSitePlus	COSMIC;CCLE	1.514	Up-regulation
STE_STE20_PAKB_PAK6_ST	Q9BY11	PACSIN1	Q9NQU5	PAK6	S346	A341S	341	Missense	distal	-5	no	4.590	4.336	PhosphoSitePlus	COSMIC	1.514	Down-regulation
STE_STE20_PAKB_PAK6_ST	Q9BY11	PACSIN1	Q9NQU5	PAK6	S346	G342E	342	Missense	distal	-4	no	4.590	4.598	PhosphoSitePlus	COSMIC	1.514	Up-regulation
STE_STE20_PAKB_PAK6_ST	P56545	CTBP2	Q9NQU5	PAK6	T88	T88I	88	Missense	central	0	yes	1.747	0.000	EPSD	COSMIC	1.514	Loss
STE_STE20_PAKB_PAK6_ST	P56545	CTBP2	Q9NQU5	PAK6	T88	E93Q	93	Missense	distal	5	no	1.747	1.711	EPSD	COSMIC	1.514	Down-regulation
STE_STE20_PAKB_PAK6_ST	P56545	CTBP2	Q9NQU5	PAK6	T88	K94N	94	Missense	distal	6	no	1.747	1.756	EPSD	COSMIC	1.514	Up-regulation
STE_STE20_PAKB_PAK6_ST	P56545	CTBP2	Q9NQU5	PAK6	T88	Y82N	82	Missense	distal	-6	no	1.747	1.678	EPSD	COSMIC;CCLE	1.514	Down-regulation
STE_STE20_PAKB_PAK6_ST	P56545	CTBP2	Q9NQU5	PAK6	T88	T84N	84	Missense	distal	-4	no	1.747	1.749	EPSD	COSMIC	1.514	Up-regulation
STE_STE20_PAKB_PAK6_ST	P56545	CTBP2	Q9NQU5	PAK6	T88	I85F	85	Missense	distal	-3	no	1.747	1.659	EPSD	COSMIC	1.514	Down-regulation
STE_STE20_PAKB_PAK6_ST	P56545	CTBP2	Q9NQU5	PAK6	T433	D437N	437	Missense	distal	4	no	1.605	1.595	EPSD	COSMIC	1.514	Down-regulation
STE_STE20_PAKB_PAK6_ST	P56545	CTBP2	Q9NQU5	PAK6	T433	E440K	440	Missense	distal	7	no	1.605	1.572	EPSD	COSMIC	1.514	Down-regulation
STE_STE20_PAKB_PAK6_ST	P10275	AR	Q9NQU5	PAK6	S310	D305N	305	Missense	distal	-5	no	1.567	1.702	EPSD	COSMIC	1.514	Up-regulation
STE_STE20_PAKB_PAK6_ST	P10275	AR	Q9NQU5	PAK6	S310	S310F	310	Missense	central	0	yes	1.567	0.000	EPSD	COSMIC	1.514	Loss
STE_STE20_PAKB_PAK6_ST	P10275	AR	Q9NQU5	PAK6	S310	E304K	304	Missense	distal	-6	no	1.567	1.632	EPSD	COSMIC	1.514	Up-regulation
STE_STE20_PAKB_PAK6_ST	P10275	AR	Q9NQU5	PAK6	S310	T306I	306	Missense	distal	-4	no	1.567	1.561	EPSD	COSMIC;GDSC;CCLE	1.514	Down-regulation
STE_STE20_PAKB_PAK6_ST	P10275	AR	Q9NQU5	PAK6	S310	F312L	312	Missense	proximal	2	no	1.567	1.430	EPSD	COSMIC	1.514	Loss
STE_STE20_PAKB_PAK6_ST	P10275	AR	Q9NQU5	PAK6	S579	T576A	576	Missense	distal	-3	no	4.575	4.556	PhosphoSitePlus	COSMIC	1.514	Down-regulation
STE_STE20_PAKB_PAK6_ST	P10275	AR	Q9NQU5	PAK6	S579	C580R	580	Missense	proximal	1	no	4.575	4.603	PhosphoSitePlus	COSMIC	1.514	Up-regulation
STE_STE20_PAKB_PAK6_ST	P10275	AR	Q9NQU5	PAK6	S579	L575I	575	Missense	distal	-4	no	4.575	4.570	PhosphoSitePlus	COSMIC	1.514	Down-regulation
STE_STE20_PAKB_PAK6_ST	P10275	AR	Q9NQU5	PAK6	S579	K581R	581	Missense	proximal	2	no	4.575	4.337	PhosphoSitePlus	COSMIC	1.514	Down-regulation
STE_STE20_PAKB_PAK6_ST	P10275	AR	Q9NQU5	PAK6	S579	F584L	584	Missense	distal	5	no	4.575	4.536	PhosphoSitePlus	COSMIC	1.514	Down-regulation
STE_STE20_PAKB_PAK6_ST	P10275	AR	Q9NQU5	PAK6	T653	S648R	648	Missense	distal	-5	no	1.346	1.576	EPSD	COSMIC	1.514	Gain
STE_STE20_PAKB_PAK6_ST	P10275	AR	Q9NQU5	PAK6	T656	K659N	659	Missense	distal	3	no	1.491	1.589	EPSD	COSMIC	1.514	Gain
STE_STE20_PAKB_PAK6_ST	Q13363	CTBP1	Q9NQU5	PAK6	T80	A73V	73	Missense	distal	-7	no	1.494	1.560	EPSD	COSMIC	1.514	Gain
STE_STE20_PAKB_PAK6_ST	Q13363	CTBP1	Q9NQU5	PAK6	S298	P296T	296	Missense	proximal	-2	no	2.054	1.992	EPSD	COSMIC	1.514	Down-regulation
STE_STE20_PAKB_PAK6_ST	P53667	LIMK1	Q9NQU5	PAK6	T261	G265R	265	Missense	distal	4	no	1.574	1.561	EPSD	COSMIC	1.514	Down-regulation
STE_STE20_PAKB_PAK6_ST	P53667	LIMK1	Q9NQU5	PAK6	T261	D260N	260	Missense	proximal	-1	no	1.574	1.579	EPSD	COSMIC	1.514	Up-regulation
STE_STE20_PAKB_PAK6_ST	P53667	LIMK1	Q9NQU5	PAK6	T261	P268T	268	Missense	distal	7	no	1.574	1.529	EPSD	COSMIC	1.514	Down-regulation
STE_STE20_PAKB_PAK6_ST	P53667	LIMK1	Q9NQU5	PAK6	T261	G265V	265	Missense	distal	4	no	1.574	1.558	EPSD	COSMIC	1.514	Down-regulation
STE_STE20_PAKB_PAK6_ST	P53667	LIMK1	Q9NQU5	PAK6	T270	G265R	265	Missense	distal	-5	no	2.045	2.272	EPSD	COSMIC	1.514	Up-regulation
STE_STE20_PAKB_PAK6_ST	P53667	LIMK1	Q9NQU5	PAK6	T270	A277T	277	Missense	distal	7	no	2.045	2.087	EPSD	COSMIC	1.514	Up-regulation
STE_STE20_PAKB_PAK6_ST	P53667	LIMK1	Q9NQU5	PAK6	T270	P276Q	276	Missense	distal	6	no	2.045	2.049	EPSD	COSMIC	1.514	Up-regulation
STE_STE20_PAKB_PAK6_ST	P53667	LIMK1	Q9NQU5	PAK6	T270	P268T	268	Missense	proximal	-2	no	2.045	1.983	EPSD	COSMIC	1.514	Down-regulation
STE_STE20_PAKB_PAK6_ST	P53667	LIMK1	Q9NQU5	PAK6	T270	G265V	265	Missense	distal	-5	no	2.045	2.139	EPSD	COSMIC	1.514	Up-regulation
STE_STE20_PAKB_PAK6_ST	P53667	LIMK1	Q9NQU5	PAK6	S296	R295W	295	Missense	proximal	-1	no	1.769	1.760	EPSD	COSMIC	1.514	Down-regulation
STE_STE20_PAKB_PAK6_ST	P53667	LIMK1	Q9NQU5	PAK6	S427	T420S	420	Missense	distal	-7	no	1.865	1.803	EPSD	COSMIC;GDSC;CCLE	1.514	Down-regulation
STE_STE20_PAKB_PAK6_ST	P53667	LIMK1	Q9NQU5	PAK6	S427	T420M	420	Missense	distal	-7	no	1.865	1.829	EPSD	COSMIC	1.514	Down-regulation
STE_STE20_PAKB_PAK6_ST	P53667	LIMK1	Q9NQU5	PAK6	S427	R422Q	422	Missense	distal	-5	no	1.865	1.756	EPSD	COSMIC	1.514	Down-regulation
STE_STE20_PAKA_PAK1_ST	P36871	PGM1	Q13153	PAK1	S134	G136E	136	Missense	proximal	2	no	20.564	19.444	EPSD	COSMIC	19.028	Down-regulation
STE_STE20_PAKA_PAK1_ST	P36871	PGM1	Q13153	PAK1	S134	P138L	138	Missense	distal	4	no	20.564	19.007	EPSD	COSMIC	19.028	Loss
STE_STE20_PAKA_PAK1_ST	P36871	PGM1	Q13153	PAK1	S334	A332P	332	Missense	proximal	-2	no	16.305	20.600	EPSD	COSMIC	19.028	Gain
STE_STE20_PAKA_PAK1_ST	P36871	PGM1	Q13153	PAK1	S334	A332T	332	Missense	proximal	-2	no	16.305	19.262	EPSD	COSMIC	19.028	Gain
STE_STE20_PAKA_PAK1_ST	P36871	PGM1	Q13153	PAK1	S408	Q407H	407	Missense	proximal	-1	no	22.089	21.000	EPSD	COSMIC	19.028	Down-regulation
STE_STE20_PAKA_PAK1_ST	P36871	PGM1	Q13153	PAK1	S408	R405H	405	Missense	distal	-3	no	22.089	16.017	EPSD	COSMIC	19.028	Loss
STE_STE20_PAKA_PAK1_ST	P36871	PGM1	Q13153	PAK1	S408	D411H	411	Missense	distal	3	no	22.089	21.058	EPSD	COSMIC	19.028	Down-regulation
STE_STE20_PAKA_PAK1_ST	P36871	PGM1	Q13153	PAK1	S408	E410K	410	Missense	proximal	2	no	22.089	22.392	EPSD	COSMIC	19.028	Up-regulation
STE_STE20_PAKA_PAK1_ST	P36871	PGM1	Q13153	PAK1	T467	D472N	472	Missense	distal	5	no	22.191	22.203	PhosphoSitePlus	COSMIC	19.028	Up-regulation
STE_STE20_PAKA_PAK1_ST	P36871	PGM1	Q13153	PAK1	T467	N473K	473	Missense	distal	6	no	22.191	22.217	PhosphoSitePlus	COSMIC	19.028	Up-regulation
STE_STE20_PAKA_PAK1_ST	P36871	PGM1	Q13153	PAK1	T467	N462T	462	Missense	distal	-5	no	22.191	21.983	PhosphoSitePlus	COSMIC	19.028	Down-regulation
STE_STE20_PAKA_PAK1_ST	P36871	PGM1	Q13153	PAK1	T467	S460L	460	Missense	distal	-7	no	22.191	21.488	PhosphoSitePlus	COSMIC	19.028	Down-regulation
STE_STE20_PAKA_PAK1_ST	P36871	PGM1	Q13153	PAK1	S505	A512T	512	Missense	distal	7	no	28.522	28.227	EPSD	COSMIC	19.028	Down-regulation
STE_STE20_PAKA_PAK1_ST	P36871	PGM1	Q13153	PAK1	S505	G511R	511	Missense	distal	6	no	28.522	27.894	EPSD	COSMIC;GDSC;CCLE	19.028	Down-regulation
STE_STE20_PAKA_PAK1_ST	P36871	PGM1	Q13153	PAK1	S505	R499Q	499	Missense	distal	-6	no	28.522	27.260	EPSD	COSMIC	19.028	Down-regulation
STE_STE20_PAKA_PAK1_ST	P36871	PGM1	Q13153	PAK1	S505	G508R	508	Missense	distal	3	no	28.522	25.936	EPSD	COSMIC	19.028	Down-regulation
STE_STE20_PAKA_PAK1_ST	P36871	PGM1	Q13153	PAK1	T513	G511R	511	Missense	proximal	-2	no	9.752	19.315	EPSD	COSMIC;GDSC;CCLE	19.028	Gain
STE_STE20_PAKA_PAK1_ST	P51114	FXR1	Q13153	PAK1	S11	V8A	8	Missense	distal	-3	no	14.435	21.697	EPSD	COSMIC	19.028	Gain
STE_STE20_PAKA_PAK1_ST	P51114	FXR1	Q13153	PAK1	S60	G62R	62	Missense	proximal	2	no	22.108	20.574	EPSD	COSMIC	19.028	Down-regulation
STE_STE20_PAKA_PAK1_ST	P51114	FXR1	Q13153	PAK1	T396	T396I	396	Missense	central	0	yes	21.243	0.000	EPSD	COSMIC	19.028	Loss
STE_STE20_PAKA_PAK1_ST	P51114	FXR1	Q13153	PAK1	T396	T396P	396	Missense	central	0	yes	21.243	0.000	EPSD	COSMIC;GDSC	19.028	Loss
STE_STE20_PAKA_PAK1_ST	P51114	FXR1	Q13153	PAK1	T396	R391W	391	Missense	distal	-5	no	21.243	22.371	EPSD	COSMIC	19.028	Up-regulation
STE_STE20_PAKA_PAK1_ST	P51114	FXR1	Q13153	PAK1	T396	R391I	391	Missense	distal	-5	no	21.243	21.695	EPSD	COSMIC	19.028	Up-regulation
STE_STE20_PAKA_PAK1_ST	P51114	FXR1	Q13153	PAK1	T396	P393S	393	Missense	distal	-3	no	21.243	18.254	EPSD	COSMIC	19.028	Loss
STE_STE20_PAKA_PAK1_ST	P51114	FXR1	Q13153	PAK1	S438	P442S	442	Missense	distal	4	no	20.036	17.686	EPSD	COSMIC	19.028	Loss
STE_STE20_PAKA_PAK1_ST	P51114	FXR1	Q13153	PAK1	S438	R440Q	440	Missense	proximal	2	no	20.036	20.372	EPSD	COSMIC	19.028	Up-regulation
STE_STE20_PAKA_PAK1_ST	P51114	FXR1	Q13153	PAK1	S448	G446V	446	Missense	proximal	-2	no	23.559	27.564	EPSD	COSMIC	19.028	Up-regulation
STE_STE20_PAKA_PAK1_ST	P51114	FXR1	Q13153	PAK1	S448	P442S	442	Missense	distal	-6	no	23.559	23.617	EPSD	COSMIC	19.028	Up-regulation
STE_STE20_PAKA_PAK1_ST	P51114	FXR1	Q13153	PAK1	S448	R447I	447	Missense	proximal	-1	no	23.559	22.103	EPSD	COSMIC	19.028	Down-regulation
STE_STE20_PAKA_PAK1_ST	P51114	FXR1	Q13153	PAK1	S448	R453H	453	Missense	distal	5	no	23.559	23.572	EPSD	COSMIC	19.028	Up-regulation
STE_STE20_PAKA_PAK1_ST	P51114	FXR1	Q13153	PAK1	S450	G446V	446	Missense	distal	-4	no	20.541	20.869	EPSD	COSMIC	19.028	Up-regulation
STE_STE20_PAKA_PAK1_ST	P51114	FXR1	Q13153	PAK1	S450	R447I	447	Missense	distal	-3	no	20.541	5.074	EPSD	COSMIC	19.028	Loss
STE_STE20_PAKA_PAK1_ST	P51114	FXR1	Q13153	PAK1	S450	R453H	453	Missense	distal	3	no	20.541	20.795	EPSD	COSMIC	19.028	Up-regulation
STE_STE20_PAKA_PAK1_ST	P51114	FXR1	Q13153	PAK1	S474	P476R	476	Missense	proximal	2	no	21.783	20.751	EPSD	COSMIC	19.028	Down-regulation
STE_STE20_PAKA_PAK1_ST	P51114	FXR1	Q13153	PAK1	S474	D471Y	471	Missense	distal	-3	no	21.783	22.971	EPSD	COSMIC;GDSC;CCLE	19.028	Up-regulation
STE_STE20_PAKA_PAK1_ST	P51114	FXR1	Q13153	PAK1	S506	R508I	508	Missense	proximal	2	no	24.627	25.163	EPSD	COSMIC	19.028	Up-regulation
STE_STE20_PAKA_PAK1_ST	P51114	FXR1	Q13153	PAK1	S506	D512E	512	Missense	distal	6	no	24.627	24.483	EPSD	COSMIC	19.028	Down-regulation
STE_STE20_PAKA_PAK1_ST	P51114	FXR1	Q13153	PAK1	T511	A515V	515	Missense	distal	4	no	30.028	30.671	EPSD	COSMIC	19.028	Up-regulation
STE_STE20_PAKA_PAK1_ST	P51114	FXR1	Q13153	PAK1	T511	R508I	508	Missense	distal	-3	no	30.028	14.561	EPSD	COSMIC	19.028	Loss
STE_STE20_PAKA_PAK1_ST	P51114	FXR1	Q13153	PAK1	T511	V516A	516	Missense	distal	5	no	30.028	30.027	EPSD	COSMIC	19.028	Down-regulation
STE_STE20_PAKA_PAK1_ST	P51114	FXR1	Q13153	PAK1	T511	D512E	512	Missense	proximal	1	no	30.028	30.102	EPSD	COSMIC	19.028	Up-regulation
STE_STE20_PAKA_PAK1_ST	P51114	FXR1	Q13153	PAK1	T557	R555M	555	Missense	proximal	-2	no	21.363	17.125	EPSD	COSMIC	19.028	Loss
STE_STE20_PAKA_PAK1_ST	P51114	FXR1	Q13153	PAK1	T557	N561K	561	Missense	distal	4	no	21.363	21.391	EPSD	COSMIC	19.028	Up-regulation
STE_STE20_PAKA_PAK1_ST	P51114	FXR1	Q13153	PAK1	T557	E564K	564	Missense	distal	7	no	21.363	21.418	EPSD	COSMIC	19.028	Up-regulation
STE_STE20_PAKA_PAK1_ST	P51114	FXR1	Q13153	PAK1	T557	E564V	564	Missense	distal	7	no	21.363	21.414	EPSD	COSMIC;GDSC;CCLE	19.028	Up-regulation
STE_STE20_PAKA_PAK1_ST	P51114	FXR1	Q13153	PAK1	T557	N552H	552	Missense	distal	-5	no	21.363	21.144	EPSD	COSMIC;GDSC;CCLE	19.028	Down-regulation
STE_STE20_PAKA_PAK1_ST	Q13153	PAK1	Q13153	PAK1	S21	T20I	20	Missense	proximal	-1	no	26.453	25.598	EPSD	COSMIC	19.028	Down-regulation
STE_STE20_PAKA_PAK1_ST	Q13153	PAK1	Q13153	PAK1	S21	M17I	17	Missense	distal	-4	no	26.453	26.884	EPSD	COSMIC	19.028	Up-regulation
STE_STE20_PAKA_PAK1_ST	Q13153	PAK1	Q13153	PAK1	S57	D52N	52	Missense	distal	-5	no	24.285	24.438	EPSD	COSMIC	19.028	Up-regulation
STE_STE20_PAKA_PAK1_ST	Q13153	PAK1	Q13153	PAK1	S57	I58T	58	Missense	proximal	1	no	24.285	24.447	EPSD	COSMIC	19.028	Up-regulation
STE_STE20_PAKA_PAK1_ST	Q13153	PAK1	Q13153	PAK1	S57	D52V	52	Missense	distal	-5	no	24.285	24.304	EPSD	COSMIC	19.028	Up-regulation
STE_STE20_PAKA_PAK1_ST	Q13153	PAK1	Q13153	PAK1	S57	S57Y	57	Missense	central	0	yes	24.285	0.000	EPSD	COSMIC	19.028	Loss
STE_STE20_PAKA_PAK1_ST	Q13153	PAK1	Q13153	PAK1	S137	S133L	133	Missense	distal	-4	no	18.967	19.121	EPSD	COSMIC	19.028	Gain
STE_STE20_PAKA_PAK1_ST	Q13153	PAK1	Q13153	PAK1	S144	K141E	141	Missense	distal	-3	no	22.030	8.238	EPSD;PhosphoSitePlus	COSMIC	19.028	Loss
STE_STE20_PAKA_PAK1_ST	Q13153	PAK1	Q13153	PAK1	S144	Y142C	142	Missense	proximal	-2	no	22.030	13.649	EPSD;PhosphoSitePlus	COSMIC	19.028	Loss
STE_STE20_PAKA_PAK1_ST	Q13153	PAK1	Q13153	PAK1	S144	E151K	151	Missense	distal	7	no	22.030	22.085	EPSD;PhosphoSitePlus	COSMIC	19.028	Up-regulation
STE_STE20_PAKA_PAK1_ST	Q13153	PAK1	Q13153	PAK1	S165	E166Q	166	Missense	proximal	1	no	20.746	20.637	EPSD	COSMIC	19.028	Down-regulation
STE_STE20_PAKA_PAK1_ST	Q13153	PAK1	Q13153	PAK1	S165	A169V	169	Missense	distal	4	no	20.746	21.389	EPSD	COSMIC	19.028	Up-regulation
STE_STE20_PAKA_PAK1_ST	Q13153	PAK1	Q13153	PAK1	S199	R203W	203	Missense	distal	4	no	21.601	23.719	PhosphoSitePlus;EPSD	COSMIC	19.028	Up-regulation
STE_STE20_PAKA_PAK1_ST	Q13153	PAK1	Q13153	PAK1	S199	K198Q	198	Missense	proximal	-1	no	21.601	20.415	PhosphoSitePlus;EPSD	COSMIC	19.028	Down-regulation
STE_STE20_PAKA_PAK1_ST	Q13153	PAK1	Q13153	PAK1	S199	Y201C	201	Missense	proximal	2	no	21.601	19.981	PhosphoSitePlus;EPSD	COSMIC	19.028	Down-regulation
STE_STE20_PAKA_PAK1_ST	Q13153	PAK1	Q13153	PAK1	S204	R203W	203	Missense	proximal	-1	no	20.824	17.203	EPSD;PhosphoSitePlus	COSMIC	19.028	Loss
STE_STE20_PAKA_PAK1_ST	Q13153	PAK1	Q13153	PAK1	S204	K198Q	198	Missense	distal	-6	no	20.824	21.620	EPSD;PhosphoSitePlus	COSMIC	19.028	Up-regulation
STE_STE20_PAKA_PAK1_ST	Q13153	PAK1	Q13153	PAK1	S204	P208L	208	Missense	distal	4	no	20.824	19.266	EPSD;PhosphoSitePlus	COSMIC	19.028	Down-regulation
STE_STE20_PAKA_PAK1_ST	Q13153	PAK1	Q13153	PAK1	S204	Y201C	201	Missense	distal	-3	no	20.824	6.636	EPSD;PhosphoSitePlus	COSMIC	19.028	Loss
STE_STE20_PAKA_PAK1_ST	Q13153	PAK1	Q13153	PAK1	T271	R272W	272	Missense	proximal	1	no	19.302	18.707	EPSD	COSMIC	19.028	Loss
STE_STE20_PAKA_PAK1_ST	Q13153	PAK1	Q13153	PAK1	T271	E274K	274	Missense	distal	3	no	19.302	19.403	EPSD	COSMIC	19.028	Up-regulation
STE_STE20_PAKA_PAK1_ST	Q13153	PAK1	Q13153	PAK1	T423	R421W	421	Missense	proximal	-2	no	30.000	17.061	EPSD;PhosphoSitePlus	COSMIC	19.028	Loss
STE_STE20_PAKA_PAK1_ST	Q13153	PAK1	Q13153	PAK1	T423	P428L	428	Missense	distal	5	no	30.000	29.985	EPSD;PhosphoSitePlus	COSMIC	19.028	Down-regulation
STE_STE20_PAKA_PAK1_ST	Q13153	PAK1	Q13153	PAK1	T423	R421Q	421	Missense	proximal	-2	no	30.000	20.793	EPSD;PhosphoSitePlus	COSMIC	19.028	Down-regulation
STE_STE20_PAKA_PAK1_ST	Q13153	PAK1	Q13153	PAK1	T423	M424I	424	Missense	proximal	1	no	30.000	30.238	EPSD;PhosphoSitePlus	COSMIC	19.028	Up-regulation
STE_STE20_PAKA_PAK1_ST	Q13153	PAK1	Q13153	PAK1	T423	E417V	417	Missense	distal	-6	no	30.000	29.162	EPSD;PhosphoSitePlus	COSMIC	19.028	Down-regulation
STE_STE20_PAKA_PAK1_ST	Q13153	PAK1	Q13153	PAK1	T423	R421K	421	Missense	proximal	-2	no	30.000	25.962	EPSD;PhosphoSitePlus	COSMIC	19.028	Down-regulation
STE_STE20_PAKA_PAK1_ST	Q13153	PAK1	Q13153	PAK1	S528	S528F	528	Missense	central	0	yes	22.482	0.000	EPSD	COSMIC	19.028	Loss
STE_STE20_PAKA_PAK1_ST	Q13153	PAK1	Q13153	PAK1	S528	L533M	533	Missense	distal	5	no	22.482	22.500	EPSD	COSMIC	19.028	Up-regulation
STE_STE20_PAKA_PAK1_ST	O15143	ARPC1B	Q13153	PAK1	T21	I25M	25	Missense	distal	4	no	21.594	21.798	PhosphoSitePlus	COSMIC	19.028	Up-regulation
STE_STE20_PAKA_PAK1_ST	P19086	GNAZ	Q13153	PAK1	S16	R21C	21	Missense	distal	5	no	28.087	28.110	PhosphoSitePlus	COSMIC	19.028	Up-regulation
STE_STE20_PAKA_PAK1_ST	P19086	GNAZ	Q13153	PAK1	S16	R17Q	17	Missense	proximal	1	no	28.087	27.752	PhosphoSitePlus	COSMIC	19.028	Down-regulation
STE_STE20_PAKA_PAK1_ST	P19086	GNAZ	Q13153	PAK1	S27	R21C	21	Missense	distal	-6	no	20.135	16.430	EPSD	COSMIC	19.028	Loss
STE_STE20_PAKA_PAK1_ST	P19086	GNAZ	Q13153	PAK1	S27	R24H	24	Missense	distal	-3	no	20.135	14.064	EPSD	COSMIC;GDSC;CCLE	19.028	Loss
STE_STE20_PAKA_PAK1_ST	P19086	GNAZ	Q13153	PAK1	T182	K189T	189	Missense	distal	7	no	22.092	21.789	EPSD	COSMIC	19.028	Down-regulation
STE_STE20_PAKA_PAK1_ST	P19086	GNAZ	Q13153	PAK1	T182	T183M	183	Missense	proximal	1	no	22.092	21.691	EPSD	COSMIC	19.028	Down-regulation
STE_STE20_PAKA_PAK1_ST	P04049	RAF1	Q13153	PAK1	S12	S12C	12	Missense	central	0	yes	23.349	0.000	EPSD	COSMIC	19.028	Loss
STE_STE20_PAKA_PAK1_ST	P04049	RAF1	Q13153	PAK1	S12	G14S	14	Missense	proximal	2	no	23.349	22.201	EPSD	COSMIC	19.028	Down-regulation
STE_STE20_PAKA_PAK1_ST	P04049	RAF1	Q13153	PAK1	S12	Q5H	5	Missense	distal	-7	no	23.349	22.522	EPSD	COSMIC	19.028	Down-regulation
STE_STE20_PAKA_PAK1_ST	P04049	RAF1	Q13153	PAK1	S43	G46D	46	Missense	distal	3	no	27.696	26.395	EPSD	COSMIC	19.028	Down-regulation
STE_STE20_PAKA_PAK1_ST	P04049	RAF1	Q13153	PAK1	S43	R41P	41	Missense	proximal	-2	no	27.696	24.171	EPSD	COSMIC	19.028	Down-regulation
STE_STE20_PAKA_PAK1_ST	P04049	RAF1	Q13153	PAK1	S43	L48F	48	Missense	distal	5	no	27.696	27.689	EPSD	COSMIC	19.028	Down-regulation
STE_STE20_PAKA_PAK1_ST	P04049	RAF1	Q13153	PAK1	S43	A42E	42	Missense	proximal	-1	no	27.696	28.312	EPSD	COSMIC	19.028	Up-regulation
STE_STE20_PAKA_PAK1_ST	P04049	RAF1	Q13153	PAK1	S199	N198D	198	Missense	proximal	-1	no	19.449	21.626	EPSD	COSMIC	19.028	Up-regulation
STE_STE20_PAKA_PAK1_ST	P04049	RAF1	Q13153	PAK1	S199	S199F	199	Missense	central	0	yes	19.449	0.000	EPSD	COSMIC	19.028	Loss
STE_STE20_PAKA_PAK1_ST	P04049	RAF1	Q13153	PAK1	S199	S204T	204	Missense	distal	5	no	19.449	19.450	EPSD	COSMIC	19.028	Up-regulation
STE_STE20_PAKA_PAK1_ST	P04049	RAF1	Q13153	PAK1	S199	T200A	200	Missense	proximal	1	no	19.449	18.954	EPSD	COSMIC	19.028	Loss
STE_STE20_PAKA_PAK1_ST	P04049	RAF1	Q13153	PAK1	S199	L194V	194	Missense	distal	-5	no	19.449	19.191	EPSD	COSMIC	19.028	Down-regulation
STE_STE20_PAKA_PAK1_ST	P04049	RAF1	Q13153	PAK1	S199	G205R	205	Missense	distal	6	no	19.449	18.821	EPSD	COSMIC	19.028	Loss
STE_STE20_PAKA_PAK1_ST	P04049	RAF1	Q13153	PAK1	S220	M217I	217	Missense	distal	-3	no	19.644	11.746	EPSD	COSMIC	19.028	Loss
STE_STE20_PAKA_PAK1_ST	P04049	RAF1	Q13153	PAK1	S233	A237T	237	Missense	distal	4	no	19.309	17.967	EPSD	COSMIC;CCLE	19.028	Loss
STE_STE20_PAKA_PAK1_ST	P04049	RAF1	Q13153	PAK1	T234	A237T	237	Missense	distal	3	no	19.290	18.044	EPSD	COSMIC;CCLE	19.028	Loss
STE_STE20_PAKA_PAK1_ST	P04049	RAF1	Q13153	PAK1	S243	S244R	244	Missense	proximal	1	no	18.914	19.316	EPSD	COSMIC	19.028	Gain
STE_STE20_PAKA_PAK1_ST	P04049	RAF1	Q13153	PAK1	S247	S244R	244	Missense	distal	-3	no	16.614	25.286	EPSD	COSMIC	19.028	Gain
STE_STE20_PAKA_PAK1_ST	P04049	RAF1	Q13153	PAK1	S257	T260I	260	Missense	distal	3	no	18.114	19.185	EPSD	COSMIC	19.028	Gain
STE_STE20_PAKA_PAK1_ST	P04049	RAF1	Q13153	PAK1	T258	T260K	260	Missense	proximal	2	no	18.882	19.951	EPSD	COSMIC	19.028	Gain
STE_STE20_PAKA_PAK1_ST	P04049	RAF1	Q13153	PAK1	T258	T260I	260	Missense	proximal	2	no	18.882	19.770	EPSD	COSMIC	19.028	Gain
STE_STE20_PAKA_PAK1_ST	P04049	RAF1	Q13153	PAK1	S259	S259A	259	Missense	central	0	yes	24.769	0.000	EPSD	COSMIC	19.028	Loss
STE_STE20_PAKA_PAK1_ST	P04049	RAF1	Q13153	PAK1	S259	P261L	261	Missense	proximal	2	no	24.769	24.937	EPSD	COSMIC	19.028	Up-regulation
STE_STE20_PAKA_PAK1_ST	P04049	RAF1	Q13153	PAK1	S259	S259C	259	Missense	central	0	yes	24.769	0.000	EPSD	COSMIC	19.028	Loss
STE_STE20_PAKA_PAK1_ST	P04049	RAF1	Q13153	PAK1	S259	S259P	259	Missense	central	0	yes	24.769	0.000	EPSD	COSMIC	19.028	Loss
STE_STE20_PAKA_PAK1_ST	P04049	RAF1	Q13153	PAK1	S259	T260K	260	Missense	proximal	1	no	24.769	24.405	EPSD	COSMIC	19.028	Down-regulation
STE_STE20_PAKA_PAK1_ST	P04049	RAF1	Q13153	PAK1	S259	P261T	261	Missense	proximal	2	no	24.769	23.384	EPSD	COSMIC	19.028	Down-regulation
STE_STE20_PAKA_PAK1_ST	P04049	RAF1	Q13153	PAK1	S259	N262K	262	Missense	distal	3	no	24.769	23.381	EPSD	COSMIC	19.028	Down-regulation
STE_STE20_PAKA_PAK1_ST	P04049	RAF1	Q13153	PAK1	S259	T260I	260	Missense	proximal	1	no	24.769	24.606	EPSD	COSMIC	19.028	Down-regulation
STE_STE20_PAKA_PAK1_ST	P04049	RAF1	Q13153	PAK1	S259	P261S	261	Missense	proximal	2	no	24.769	24.123	EPSD	COSMIC	19.028	Down-regulation
STE_STE20_PAKA_PAK1_ST	P04049	RAF1	Q13153	PAK1	S259	V263A	263	Missense	distal	4	no	24.769	24.125	EPSD	COSMIC	19.028	Down-regulation
STE_STE20_PAKA_PAK1_ST	P04049	RAF1	Q13153	PAK1	S259	V263D	263	Missense	distal	4	no	24.769	23.899	EPSD	COSMIC	19.028	Down-regulation
STE_STE20_PAKA_PAK1_ST	P04049	RAF1	Q13153	PAK1	T310	V312E	312	Missense	proximal	2	no	19.080	18.133	EPSD	COSMIC	19.028	Loss
STE_STE20_PAKA_PAK1_ST	P04049	RAF1	Q13153	PAK1	S338	R333C	333	Missense	distal	-5	no	27.636	28.392	EPSD;PhosphoSitePlus	COSMIC	19.028	Up-regulation
STE_STE20_PAKA_PAK1_ST	P04049	RAF1	Q13153	PAK1	S338	Q335H	335	Missense	distal	-3	no	27.636	30.289	EPSD;PhosphoSitePlus	COSMIC;GDSC;CCLE	19.028	Up-regulation
STE_STE20_PAKA_PAK1_ST	P04049	RAF1	Q13153	PAK1	S339	R333C	333	Missense	distal	-6	no	26.983	23.278	PhosphoSitePlus;EPSD	COSMIC	19.028	Down-regulation
STE_STE20_PAKA_PAK1_ST	P04049	RAF1	Q13153	PAK1	S339	Q335H	335	Missense	distal	-4	no	26.983	27.017	PhosphoSitePlus;EPSD	COSMIC;GDSC;CCLE	19.028	Up-regulation
STE_STE20_PAKA_PAK1_ST	P04049	RAF1	Q13153	PAK1	S357	S359C	359	Missense	proximal	2	no	18.996	19.628	EPSD	COSMIC	19.028	Gain
STE_STE20_PAKA_PAK1_ST	P04049	RAF1	Q13153	PAK1	T362	G361R	361	Missense	proximal	-1	no	15.564	19.632	EPSD	COSMIC	19.028	Gain
STE_STE20_PAKA_PAK1_ST	P04049	RAF1	Q13153	PAK1	S604	Q601R	601	Missense	distal	-3	no	13.984	22.708	EPSD	COSMIC	19.028	Gain
STE_STE20_PAKA_PAK1_ST	Q13418	ILK	Q13153	PAK1	T167	K170N	170	Missense	distal	3	no	20.162	21.550	EPSD	COSMIC	19.028	Up-regulation
STE_STE20_PAKA_PAK1_ST	Q13418	ILK	Q13153	PAK1	T173	R176L	176	Missense	distal	3	no	19.002	20.637	EPSD;PhosphoSitePlus	COSMIC	19.028	Gain
STE_STE20_PAKA_PAK1_ST	Q13418	ILK	Q13153	PAK1	T173	R176W	176	Missense	distal	3	no	19.002	21.405	EPSD;PhosphoSitePlus	COSMIC	19.028	Gain
STE_STE20_PAKA_PAK1_ST	Q13418	ILK	Q13153	PAK1	S246	P252S	252	Missense	distal	6	no	22.329	22.081	PhosphoSitePlus;EPSD	COSMIC	19.028	Down-regulation
STE_STE20_PAKA_PAK1_ST	Q13418	ILK	Q13153	PAK1	S336	F342L	342	Missense	distal	6	no	21.384	21.280	EPSD	COSMIC	19.028	Down-regulation
STE_STE20_PAKA_PAK1_ST	Q13418	ILK	Q13153	PAK1	S336	K341Q	341	Missense	distal	5	no	21.384	21.373	EPSD	COSMIC	19.028	Down-regulation
STE_STE20_PAKA_PAK1_ST	Q92934	BAD	Q13153	PAK1	S74	A78E	78	Missense	distal	4	no	20.464	19.738	EPSD;PhosphoSitePlus	COSMIC	19.028	Down-regulation
STE_STE20_PAKA_PAK1_ST	Q92934	BAD	Q13153	PAK1	S75	A78E	78	Missense	distal	3	no	25.891	24.410	PhosphoSitePlus;EPSD	COSMIC	19.028	Down-regulation
STE_STE20_PAKA_PAK1_ST	Q92934	BAD	Q13153	PAK1	S97	P102L	102	Missense	distal	5	no	20.391	20.376	EPSD	COSMIC	19.028	Down-regulation
STE_STE20_PAKA_PAK1_ST	Q92934	BAD	Q13153	PAK1	S97	S97P	97	Missense	central	0	yes	20.391	0.000	EPSD	COSMIC	19.028	Loss
STE_STE20_PAKA_PAK1_ST	Q92934	BAD	Q13153	PAK1	S97	R98H	98	Missense	proximal	1	no	20.391	20.129	EPSD	COSMIC	19.028	Down-regulation
STE_STE20_PAKA_PAK1_ST	Q92934	BAD	Q13153	PAK1	S97	P101S	101	Missense	distal	4	no	20.391	18.041	EPSD	COSMIC	19.028	Loss
STE_STE20_PAKA_PAK1_ST	Q92934	BAD	Q13153	PAK1	S99	P102L	102	Missense	distal	3	no	26.257	25.671	EPSD;PhosphoSitePlus	COSMIC	19.028	Down-regulation
STE_STE20_PAKA_PAK1_ST	Q92934	BAD	Q13153	PAK1	S99	S97P	97	Missense	proximal	-2	no	26.257	30.885	EPSD;PhosphoSitePlus	COSMIC	19.028	Up-regulation
STE_STE20_PAKA_PAK1_ST	Q92934	BAD	Q13153	PAK1	S99	R98H	98	Missense	proximal	-1	no	26.257	23.450	EPSD;PhosphoSitePlus	COSMIC	19.028	Down-regulation
STE_STE20_PAKA_PAK1_ST	Q92934	BAD	Q13153	PAK1	S99	P101S	101	Missense	proximal	2	no	26.257	25.612	EPSD;PhosphoSitePlus	COSMIC	19.028	Down-regulation
STE_STE20_PAKA_PAK1_ST	Q92934	BAD	Q13153	PAK1	S118	S124F	124	Missense	distal	6	no	30.333	30.709	EPSD;PhosphoSitePlus	COSMIC	19.028	Up-regulation
STE_STE20_PAKA_PAK1_ST	Q92934	BAD	Q13153	PAK1	S134	K127N	127	Missense	distal	-7	no	25.807	25.190	EPSD;PhosphoSitePlus	COSMIC	19.028	Down-regulation
STE_STE20_PAKA_PAK1_ST	Q92934	BAD	Q13153	PAK1	S134	K133N	133	Missense	proximal	-1	no	25.807	22.454	EPSD;PhosphoSitePlus	COSMIC	19.028	Down-regulation
STE_STE20_PAKA_PAK1_ST	Q92934	BAD	Q13153	PAK1	S144	W147R	147	Missense	distal	3	no	20.524	18.120	EPSD	COSMIC	19.028	Loss
STE_STE20_PAKA_PAK1_ST	Q92974	ARHGEF2	Q13153	PAK1	T103	A104T	104	Missense	proximal	1	no	19.427	19.922	EPSD	COSMIC;CCLE	19.028	Up-regulation
STE_STE20_PAKA_PAK1_ST	Q92974	ARHGEF2	Q13153	PAK1	T103	K100M	100	Missense	distal	-3	no	19.427	13.045	EPSD	COSMIC	19.028	Loss
STE_STE20_PAKA_PAK1_ST	Q92974	ARHGEF2	Q13153	PAK1	T103	A96V	96	Missense	distal	-7	no	19.427	17.997	EPSD	COSMIC	19.028	Loss
STE_STE20_PAKA_PAK1_ST	Q92974	ARHGEF2	Q13153	PAK1	S122	Y125S	125	Missense	distal	3	no	25.387	21.608	EPSD	COSMIC	19.028	Down-regulation
STE_STE20_PAKA_PAK1_ST	Q92974	ARHGEF2	Q13153	PAK1	S122	D128Y	128	Missense	distal	6	no	25.387	25.991	EPSD	COSMIC	19.028	Up-regulation
STE_STE20_PAKA_PAK1_ST	Q92974	ARHGEF2	Q13153	PAK1	S122	D128E	128	Missense	distal	6	no	25.387	25.243	EPSD	COSMIC	19.028	Down-regulation
STE_STE20_PAKA_PAK1_ST	Q92974	ARHGEF2	Q13153	PAK1	S122	S122L	122	Missense	central	0	yes	25.387	0.000	EPSD	COSMIC	19.028	Loss
STE_STE20_PAKA_PAK1_ST	Q92974	ARHGEF2	Q13153	PAK1	S133	S137F	137	Missense	distal	4	no	23.146	24.610	EPSD	COSMIC	19.028	Up-regulation
STE_STE20_PAKA_PAK1_ST	Q92974	ARHGEF2	Q13153	PAK1	S133	R131W	131	Missense	proximal	-2	no	23.146	10.207	EPSD	COSMIC;CCLE	19.028	Loss
STE_STE20_PAKA_PAK1_ST	Q92974	ARHGEF2	Q13153	PAK1	S133	D128Y	128	Missense	distal	-5	no	23.146	23.321	EPSD	COSMIC	19.028	Up-regulation
STE_STE20_PAKA_PAK1_ST	Q92974	ARHGEF2	Q13153	PAK1	S133	D128E	128	Missense	distal	-5	no	23.146	22.720	EPSD	COSMIC	19.028	Down-regulation
STE_STE20_PAKA_PAK1_ST	Q92974	ARHGEF2	Q13153	PAK1	S172	S174P	174	Missense	proximal	2	no	24.476	25.121	EPSD	COSMIC	19.028	Up-regulation
STE_STE20_PAKA_PAK1_ST	Q92974	ARHGEF2	Q13153	PAK1	S172	R168L	168	Missense	distal	-4	no	24.476	24.163	EPSD	COSMIC	19.028	Down-regulation
STE_STE20_PAKA_PAK1_ST	Q92974	ARHGEF2	Q13153	PAK1	S172	T175K	175	Missense	distal	3	no	24.476	24.342	EPSD	COSMIC	19.028	Down-regulation
STE_STE20_PAKA_PAK1_ST	Q92974	ARHGEF2	Q13153	PAK1	T184	R183S	183	Missense	proximal	-1	no	20.791	19.710	EPSD	COSMIC	19.028	Down-regulation
STE_STE20_PAKA_PAK1_ST	Q92974	ARHGEF2	Q13153	PAK1	T184	S186F	186	Missense	proximal	2	no	20.791	20.875	EPSD	COSMIC	19.028	Up-regulation
STE_STE20_PAKA_PAK1_ST	Q92974	ARHGEF2	Q13153	PAK1	S186	R183S	183	Missense	distal	-3	no	21.191	12.519	EPSD	COSMIC	19.028	Loss
STE_STE20_PAKA_PAK1_ST	Q92974	ARHGEF2	Q13153	PAK1	S186	S186F	186	Missense	central	0	yes	21.191	0.000	EPSD	COSMIC	19.028	Loss
STE_STE20_PAKA_PAK1_ST	Q92974	ARHGEF2	Q13153	PAK1	S295	Q296H	296	Missense	proximal	1	no	24.588	24.662	EPSD	COSMIC;CCLE	19.028	Up-regulation
STE_STE20_PAKA_PAK1_ST	Q92974	ARHGEF2	Q13153	PAK1	S295	R300C	300	Missense	distal	5	no	24.588	24.611	EPSD	COSMIC	19.028	Up-regulation
STE_STE20_PAKA_PAK1_ST	Q92974	ARHGEF2	Q13153	PAK1	S295	R292C	292	Missense	distal	-3	no	24.588	4.632	EPSD	COSMIC	19.028	Loss
STE_STE20_PAKA_PAK1_ST	Q92974	ARHGEF2	Q13153	PAK1	S295	Q296E	296	Missense	proximal	1	no	24.588	24.696	EPSD	COSMIC;CCLE	19.028	Up-regulation
STE_STE20_PAKA_PAK1_ST	Q92974	ARHGEF2	Q13153	PAK1	T392	L385P	385	Missense	distal	-7	no	19.749	20.194	EPSD	COSMIC	19.028	Up-regulation
STE_STE20_PAKA_PAK1_ST	Q92974	ARHGEF2	Q13153	PAK1	T455	T455K	455	Missense	central	0	yes	20.573	0.000	EPSD	COSMIC	19.028	Loss
STE_STE20_PAKA_PAK1_ST	Q92974	ARHGEF2	Q13153	PAK1	T455	M449I	449	Missense	distal	-6	no	20.573	19.898	EPSD	COSMIC	19.028	Down-regulation
STE_STE20_PAKA_PAK1_ST	Q92974	ARHGEF2	Q13153	PAK1	S645	R642C	642	Missense	distal	-3	no	19.400	-0.555	EPSD	COSMIC	19.028	Loss
STE_STE20_PAKA_PAK1_ST	Q92974	ARHGEF2	Q13153	PAK1	S645	S645F	645	Missense	central	0	yes	19.400	0.000	EPSD	COSMIC	19.028	Loss
STE_STE20_PAKA_PAK1_ST	Q92974	ARHGEF2	Q13153	PAK1	S691	E688K	688	Missense	distal	-3	no	11.055	24.847	EPSD	COSMIC	19.028	Gain
STE_STE20_PAKA_PAK1_ST	Q92974	ARHGEF2	Q13153	PAK1	S886	R885W	885	Missense	proximal	-1	no	31.453	27.833	PhosphoSitePlus;EPSD	COSMIC	19.028	Down-regulation
STE_STE20_PAKA_PAK1_ST	Q92974	ARHGEF2	Q13153	PAK1	S886	R883Q	883	Missense	distal	-3	no	31.453	22.729	PhosphoSitePlus;EPSD	COSMIC	19.028	Down-regulation
STE_STE20_PAKA_PAK1_ST	Q92974	ARHGEF2	Q13153	PAK1	S886	R884C	884	Missense	proximal	-2	no	31.453	18.733	PhosphoSitePlus;EPSD	COSMIC	19.028	Loss
STE_STE20_PAKA_PAK1_ST	Q92974	ARHGEF2	Q13153	PAK1	S886	R884H	884	Missense	proximal	-2	no	31.453	26.040	PhosphoSitePlus;EPSD	COSMIC	19.028	Down-regulation
STE_STE20_PAKA_PAK1_ST	Q92974	ARHGEF2	Q13153	PAK1	S886	R885C	885	Missense	proximal	-1	no	31.453	27.234	PhosphoSitePlus;EPSD	COSMIC;CCLE	19.028	Down-regulation
STE_STE20_PAKA_PAK1_ST	Q92974	ARHGEF2	Q13153	PAK1	S886	L887F	887	Missense	proximal	1	no	31.453	31.543	PhosphoSitePlus;EPSD	COSMIC	19.028	Up-regulation
STE_STE20_PAKA_PAK1_ST	Q92974	ARHGEF2	Q13153	PAK1	S886	P882L	882	Missense	distal	-4	no	31.453	31.659	PhosphoSitePlus;EPSD	COSMIC	19.028	Up-regulation
STE_STE20_PAKA_PAK1_ST	Q92974	ARHGEF2	Q13153	PAK1	S886	P888S	888	Missense	proximal	2	no	31.453	30.808	PhosphoSitePlus;EPSD	COSMIC	19.028	Down-regulation
STE_STE20_PAKA_PAK1_ST	Q92974	ARHGEF2	Q13153	PAK1	S886	P888L	888	Missense	proximal	2	no	31.453	31.621	PhosphoSitePlus;EPSD	COSMIC	19.028	Up-regulation
STE_STE20_PAKA_PAK1_ST	Q92974	ARHGEF2	Q13153	PAK1	S956	S952R	952	Missense	distal	-4	no	22.322	22.789	EPSD	COSMIC	19.028	Up-regulation
STE_STE20_PAKA_PAK1_ST	Q92974	ARHGEF2	Q13153	PAK1	S956	G951E	951	Missense	distal	-5	no	22.322	21.464	EPSD	COSMIC	19.028	Down-regulation
STE_STE20_PAKA_PAK1_ST	Q92974	ARHGEF2	Q13153	PAK1	S956	S952T	952	Missense	distal	-4	no	22.322	22.835	EPSD	COSMIC	19.028	Up-regulation
STE_STE20_PAKA_PAK1_ST	Q92974	ARHGEF2	Q13153	PAK1	S956	L955V	955	Missense	proximal	-1	no	22.322	19.454	EPSD	COSMIC	19.028	Down-regulation
STE_STE20_PAKA_PAK1_ST	Q92974	ARHGEF2	Q13153	PAK1	S960	L955V	955	Missense	distal	-5	no	19.160	18.902	EPSD	COSMIC	19.028	Loss
STE_STE20_PAKA_PAK1_ST	Q13233	MAP3K1	Q13153	PAK1	S11	S10L	10	Missense	proximal	-1	no	21.994	22.942	EPSD	COSMIC	19.028	Up-regulation
STE_STE20_PAKA_PAK1_ST	Q13233	MAP3K1	Q13153	PAK1	S11	A17V	17	Missense	distal	6	no	21.994	22.315	EPSD	COSMIC	19.028	Up-regulation
STE_STE20_PAKA_PAK1_ST	Q13233	MAP3K1	Q13153	PAK1	S21	G25D	25	Missense	distal	4	no	23.571	23.114	EPSD	COSMIC	19.028	Down-regulation
STE_STE20_PAKA_PAK1_ST	Q13233	MAP3K1	Q13153	PAK1	S21	A17V	17	Missense	distal	-4	no	23.571	23.383	EPSD	COSMIC	19.028	Down-regulation
STE_STE20_PAKA_PAK1_ST	Q13233	MAP3K1	Q13153	PAK1	S21	G28V	28	Missense	distal	7	no	23.571	23.522	EPSD	COSMIC	19.028	Down-regulation
STE_STE20_PAKA_PAK1_ST	Q13233	MAP3K1	Q13153	PAK1	S67	R60Q	60	Missense	distal	-7	no	23.986	23.463	PhosphoSitePlus	COSMIC	19.028	Down-regulation
STE_STE20_PAKA_PAK1_ST	Q13233	MAP3K1	Q13153	PAK1	S67	Q72L	72	Missense	distal	5	no	23.986	24.002	PhosphoSitePlus	COSMIC	19.028	Up-regulation
STE_STE20_PAKA_PAK1_ST	Q13233	MAP3K1	Q13153	PAK1	S67	K64E	64	Missense	distal	-3	no	23.986	10.195	PhosphoSitePlus	COSMIC	19.028	Loss
STE_STE20_PAKA_PAK1_ST	Q13233	MAP3K1	Q13153	PAK1	S67	R66W	66	Missense	proximal	-1	no	23.986	20.366	PhosphoSitePlus	COSMIC	19.028	Down-regulation
STE_STE20_PAKA_PAK1_ST	Q13233	MAP3K1	Q13153	PAK1	S133	S133G	133	Missense	central	0	yes	19.655	0.000	EPSD	COSMIC	19.028	Loss
STE_STE20_PAKA_PAK1_ST	Q13233	MAP3K1	Q13153	PAK1	S250	N255S	255	Missense	distal	5	no	22.907	22.887	EPSD	COSMIC	19.028	Down-regulation
STE_STE20_PAKA_PAK1_ST	Q13233	MAP3K1	Q13153	PAK1	S250	G254D	254	Missense	distal	4	no	22.907	22.450	EPSD	COSMIC	19.028	Down-regulation
STE_STE20_PAKA_PAK1_ST	Q13233	MAP3K1	Q13153	PAK1	S250	P251T	251	Missense	proximal	1	no	22.907	23.434	EPSD	COSMIC	19.028	Up-regulation
STE_STE20_PAKA_PAK1_ST	Q13233	MAP3K1	Q13153	PAK1	S250	G247D	247	Missense	distal	-3	no	22.907	23.828	EPSD	COSMIC	19.028	Up-regulation
STE_STE20_PAKA_PAK1_ST	Q13233	MAP3K1	Q13153	PAK1	S250	G247V	247	Missense	distal	-3	no	22.907	16.899	EPSD	COSMIC	19.028	Loss
STE_STE20_PAKA_PAK1_ST	Q13233	MAP3K1	Q13153	PAK1	S250	R249G	249	Missense	proximal	-1	no	22.907	18.839	EPSD	COSMIC	19.028	Loss
STE_STE20_PAKA_PAK1_ST	Q13233	MAP3K1	Q13153	PAK1	S252	P251T	251	Missense	proximal	-1	no	16.917	20.640	EPSD	COSMIC	19.028	Gain
STE_STE20_PAKA_PAK1_ST	Q13233	MAP3K1	Q13153	PAK1	S264	P267L	267	Missense	distal	3	no	20.930	20.343	EPSD	COSMIC	19.028	Down-regulation
STE_STE20_PAKA_PAK1_ST	Q13233	MAP3K1	Q13153	PAK1	S264	S266F	266	Missense	proximal	2	no	20.930	21.013	EPSD	COSMIC	19.028	Up-regulation
STE_STE20_PAKA_PAK1_ST	Q13233	MAP3K1	Q13153	PAK1	S266	P267L	267	Missense	proximal	1	no	19.092	19.379	EPSD	COSMIC	19.028	Up-regulation
STE_STE20_PAKA_PAK1_ST	Q13233	MAP3K1	Q13153	PAK1	S266	S266F	266	Missense	central	0	yes	19.092	0.000	EPSD	COSMIC	19.028	Loss
STE_STE20_PAKA_PAK1_ST	Q13233	MAP3K1	Q13153	PAK1	S275	G282D	282	Missense	distal	7	no	28.994	28.910	EPSD	COSMIC	19.028	Down-regulation
STE_STE20_PAKA_PAK1_ST	Q13233	MAP3K1	Q13153	PAK1	S275	Q280H	280	Missense	distal	5	no	28.994	29.009	EPSD	COSMIC	19.028	Up-regulation
STE_STE20_PAKA_PAK1_ST	Q13233	MAP3K1	Q13153	PAK1	S292	S292L	292	Missense	central	0	yes	19.861	0.000	EPSD	COSMIC	19.028	Loss
STE_STE20_PAKA_PAK1_ST	Q13233	MAP3K1	Q13153	PAK1	S292	D294H	294	Missense	proximal	2	no	19.861	19.458	EPSD	COSMIC	19.028	Down-regulation
STE_STE20_PAKA_PAK1_ST	Q13233	MAP3K1	Q13153	PAK1	S292	P291S	291	Missense	proximal	-1	no	19.861	23.104	EPSD	COSMIC	19.028	Up-regulation
STE_STE20_PAKA_PAK1_ST	Q13233	MAP3K1	Q13153	PAK1	S397	R396C	396	Missense	proximal	-1	no	23.250	19.031	EPSD	COSMIC	19.028	Down-regulation
STE_STE20_PAKA_PAK1_ST	Q13233	MAP3K1	Q13153	PAK1	S397	H393Q	393	Missense	distal	-4	no	23.250	23.216	EPSD	COSMIC	19.028	Down-regulation
STE_STE20_PAKA_PAK1_ST	Q13233	MAP3K1	Q13153	PAK1	S398	R405C	405	Missense	distal	7	no	24.830	25.068	EPSD	COSMIC	19.028	Up-regulation
STE_STE20_PAKA_PAK1_ST	Q13233	MAP3K1	Q13153	PAK1	S398	R396C	396	Missense	proximal	-2	no	24.830	12.110	EPSD	COSMIC	19.028	Loss
STE_STE20_PAKA_PAK1_ST	Q13233	MAP3K1	Q13153	PAK1	S398	H393Q	393	Missense	distal	-5	no	24.830	24.482	EPSD	COSMIC	19.028	Down-regulation
STE_STE20_PAKA_PAK1_ST	Q13233	MAP3K1	Q13153	PAK1	S796	L802F	802	Missense	distal	6	no	20.444	20.548	EPSD	COSMIC	19.028	Up-regulation
STE_STE20_PAKA_PAK1_ST	Q13233	MAP3K1	Q13153	PAK1	S796	R790K	790	Missense	distal	-6	no	20.444	18.386	EPSD	COSMIC	19.028	Loss
STE_STE20_PAKA_PAK1_ST	Q13233	MAP3K1	Q13153	PAK1	S796	Y791C	791	Missense	distal	-5	no	20.444	20.512	EPSD	COSMIC	19.028	Up-regulation
STE_STE20_PAKA_PAK1_ST	Q13233	MAP3K1	Q13153	PAK1	S1026	S1026Y	1026	Missense	central	0	yes	26.418	0.000	EPSD	COSMIC	19.028	Loss
STE_STE20_PAKA_PAK1_ST	Q13233	MAP3K1	Q13153	PAK1	S1026	R1023H	1023	Missense	distal	-3	no	26.418	20.347	EPSD	COSMIC	19.028	Down-regulation
STE_STE20_PAKA_PAK1_ST	Q13233	MAP3K1	Q13153	PAK1	S1026	F1025I	1025	Missense	proximal	-1	no	26.418	25.245	EPSD	COSMIC	19.028	Down-regulation
STE_STE20_PAKA_PAK1_ST	Q13233	MAP3K1	Q13153	PAK1	S1026	K1024R	1024	Missense	proximal	-2	no	26.418	30.456	EPSD	COSMIC	19.028	Up-regulation
STE_STE20_PAKA_PAK1_ST	Q13233	MAP3K1	Q13153	PAK1	S1026	P1019L	1019	Missense	distal	-7	no	26.418	25.973	EPSD	COSMIC	19.028	Down-regulation
STE_STE20_PAKA_PAK1_ST	Q13233	MAP3K1	Q13153	PAK1	S1397	R1394S	1394	Missense	distal	-3	no	19.572	10.901	EPSD	COSMIC	19.028	Loss
STE_STE20_PAKA_PAK1_ST	Q99426	TBCB	Q13153	PAK1	S110	Y107F	107	Missense	distal	-3	no	19.508	20.116	EPSD	COSMIC	19.028	Up-regulation
STE_STE20_PAKA_PAK1_ST	Q99426	TBCB	Q13153	PAK1	S110	V104L	104	Missense	distal	-6	no	19.508	19.027	EPSD	COSMIC	19.028	Loss
STE_STE20_PAKA_PAK1_ST	Q99426	TBCB	Q13153	PAK1	S110	R117W	117	Missense	distal	7	no	19.508	19.689	EPSD	COSMIC	19.028	Up-regulation
STE_STE20_PAKA_PAK1_ST	Q99426	TBCB	Q13153	PAK1	S110	R117L	117	Missense	distal	7	no	19.508	19.656	EPSD	COSMIC	19.028	Up-regulation
STE_STE20_PAKA_PAK1_ST	Q99426	TBCB	Q13153	PAK1	S128	R122C	122	Missense	distal	-6	no	20.192	16.487	PhosphoSitePlus;EPSD	COSMIC	19.028	Loss
STE_STE20_PAKA_PAK1_ST	Q99661	KIF2C	Q13153	PAK1	S95	R93W	93	Missense	proximal	-2	no	23.691	10.753	EPSD	COSMIC	19.028	Loss
STE_STE20_PAKA_PAK1_ST	Q99661	KIF2C	Q13153	PAK1	S95	K92Q	92	Missense	distal	-3	no	23.691	16.154	EPSD	COSMIC	19.028	Loss
STE_STE20_PAKA_PAK1_ST	Q99661	KIF2C	Q13153	PAK1	S95	S98F	98	Missense	distal	3	no	23.691	24.272	EPSD	COSMIC	19.028	Up-regulation
STE_STE20_PAKA_PAK1_ST	Q99661	KIF2C	Q13153	PAK1	S95	A102V	102	Missense	distal	7	no	23.691	23.695	EPSD	COSMIC	19.028	Up-regulation
STE_STE20_PAKA_PAK1_ST	Q99661	KIF2C	Q13153	PAK1	S144	P147S	147	Missense	distal	3	no	22.791	20.411	EPSD	COSMIC	19.028	Down-regulation
STE_STE20_PAKA_PAK1_ST	Q99661	KIF2C	Q13153	PAK1	S144	A137T	137	Missense	distal	-7	no	22.791	22.934	EPSD	COSMIC	19.028	Up-regulation
STE_STE20_PAKA_PAK1_ST	Q99661	KIF2C	Q13153	PAK1	S144	S139F	139	Missense	distal	-5	no	22.791	23.221	EPSD	COSMIC	19.028	Up-regulation
STE_STE20_PAKA_PAK1_ST	Q99661	KIF2C	Q13153	PAK1	S166	E170Q	170	Missense	distal	4	no	22.559	21.994	EPSD	COSMIC	19.028	Down-regulation
STE_STE20_PAKA_PAK1_ST	Q99661	KIF2C	Q13153	PAK1	S166	L162F	162	Missense	distal	-4	no	22.559	22.687	EPSD	COSMIC	19.028	Up-regulation
STE_STE20_PAKA_PAK1_ST	Q99661	KIF2C	Q13153	PAK1	S166	E167K	167	Missense	proximal	1	no	22.559	22.429	EPSD	COSMIC	19.028	Down-regulation
STE_STE20_PAKA_PAK1_ST	Q99661	KIF2C	Q13153	PAK1	S180	A182S	182	Missense	proximal	2	no	23.427	22.522	EPSD	COSMIC	19.028	Down-regulation
STE_STE20_PAKA_PAK1_ST	Q99661	KIF2C	Q13153	PAK1	S180	N186D	186	Missense	distal	6	no	23.427	23.282	EPSD	COSMIC	19.028	Down-regulation
STE_STE20_PAKA_PAK1_ST	Q99661	KIF2C	Q13153	PAK1	S180	S179R	179	Missense	proximal	-1	no	23.427	24.507	EPSD	COSMIC	19.028	Up-regulation
STE_STE20_PAKA_PAK1_ST	Q99661	KIF2C	Q13153	PAK1	S181	S179R	179	Missense	proximal	-2	no	15.098	23.250	EPSD	COSMIC	19.028	Gain
STE_STE20_PAKA_PAK1_ST	Q99661	KIF2C	Q13153	PAK1	S192	N186D	186	Missense	distal	-6	no	28.284	28.122	PhosphoSitePlus;EPSD	COSMIC	19.028	Down-regulation
STE_STE20_PAKA_PAK1_ST	Q99661	KIF2C	Q13153	PAK1	S192	E199K	199	Missense	distal	7	no	28.284	28.339	PhosphoSitePlus;EPSD	COSMIC	19.028	Up-regulation
STE_STE20_PAKA_PAK1_ST	Q99661	KIF2C	Q13153	PAK1	S192	V188F	188	Missense	distal	-4	no	28.284	28.657	PhosphoSitePlus;EPSD	COSMIC	19.028	Up-regulation
STE_STE20_PAKA_PAK1_ST	Q99661	KIF2C	Q13153	PAK1	S192	R189L	189	Missense	distal	-3	no	28.284	21.793	PhosphoSitePlus;EPSD	COSMIC	19.028	Down-regulation
STE_STE20_PAKA_PAK1_ST	Q99661	KIF2C	Q13153	PAK1	T328	V324I	324	Missense	distal	-4	no	24.542	24.871	EPSD	COSMIC	19.028	Up-regulation
STE_STE20_PAKA_PAK1_ST	Q99661	KIF2C	Q13153	PAK1	S489	S489F	489	Missense	central	0	yes	20.871	0.000	EPSD	COSMIC	19.028	Loss
STE_STE20_PAKA_PAK1_ST	Q99661	KIF2C	Q13153	PAK1	S489	G495W	495	Missense	distal	6	no	20.871	21.135	EPSD	COSMIC	19.028	Up-regulation
STE_STE20_PAKA_PAK1_ST	Q99661	KIF2C	Q13153	PAK1	S489	F488L	488	Missense	proximal	-1	no	20.871	21.022	EPSD	COSMIC	19.028	Up-regulation
STE_STE20_PAKA_PAK1_ST	Q99661	KIF2C	Q13153	PAK1	S551	F552S	552	Missense	proximal	1	no	24.513	24.253	EPSD	COSMIC;CCLE	19.028	Down-regulation
STE_STE20_PAKA_PAK1_ST	P18669	PGAM1	Q13153	PAK1	S118	V112M	112	Missense	distal	-6	no	23.471	22.811	EPSD;PhosphoSitePlus	COSMIC;GDSC;CCLE	19.028	Down-regulation
STE_STE20_PAKA_PAK1_ST	P78545	ELF3	Q13153	PAK1	S207	S206G	206	Missense	proximal	-1	no	22.411	19.423	PhosphoSitePlus	COSMIC	19.028	Down-regulation
STE_STE20_PAKA_PAK1_ST	P78545	ELF3	Q13153	PAK1	S207	S207F	207	Missense	central	0	yes	22.411	0.000	PhosphoSitePlus	COSMIC	19.028	Loss
STE_STE20_PAKA_PAK1_ST	P78545	ELF3	Q13153	PAK1	S207	S212F	212	Missense	distal	5	no	22.411	22.418	PhosphoSitePlus	COSMIC	19.028	Up-regulation
STE_STE20_PAKA_PAK1_ST	P78545	ELF3	Q13153	PAK1	S207	G213S	213	Missense	distal	6	no	22.411	22.048	PhosphoSitePlus	COSMIC	19.028	Down-regulation
STE_STE20_PAKA_PAK1_ST	P78545	ELF3	Q13153	PAK1	S254	S254G	254	Missense	central	0	yes	24.714	0.000	EPSD	COSMIC	19.028	Loss
STE_STE20_PAKA_PAK1_ST	P78545	ELF3	Q13153	PAK1	S254	R251Q	251	Missense	distal	-3	no	24.714	15.990	EPSD	COSMIC	19.028	Loss
STE_STE20_PAKA_PAK1_ST	P46108	CRK	Q13153	PAK1	S41	D39N	39	Missense	proximal	-2	no	23.881	24.622	PhosphoSitePlus	COSMIC	19.028	Up-regulation
STE_STE20_PAKA_PAK1_ST	P46108	CRK	Q13153	PAK1	S194	A195T	195	Missense	proximal	1	no	20.158	20.653	EPSD	COSMIC	19.028	Up-regulation
STE_STE20_PAKA_PAK1_ST	P46108	CRK	Q13153	PAK1	S194	S194F	194	Missense	central	0	yes	20.158	0.000	EPSD	COSMIC	19.028	Loss
STE_STE20_PAKA_PAK1_ST	P35222	CTNNB1	Q13153	PAK1	S45	T42R	42	Missense	distal	-3	no	13.491	19.749	EPSD	COSMIC	19.028	Gain
STE_STE20_PAKA_PAK1_ST	P35222	CTNNB1	Q13153	PAK1	S47	S45T	45	Missense	proximal	-2	no	18.676	21.965	EPSD	COSMIC	19.028	Gain
STE_STE20_PAKA_PAK1_ST	P35222	CTNNB1	Q13153	PAK1	S47	A43T	43	Missense	distal	-4	no	18.676	19.092	EPSD	COSMIC	19.028	Gain
STE_STE20_PAKA_PAK1_ST	P35222	CTNNB1	Q13153	PAK1	S47	K49L	49	Missense	proximal	2	no	18.676	19.159	EPSD	COSMIC	19.028	Gain
STE_STE20_PAKA_PAK1_ST	P35222	CTNNB1	Q13153	PAK1	S47	S45E	45	Missense	proximal	-2	no	18.676	20.308	EPSD	COSMIC	19.028	Gain
STE_STE20_PAKA_PAK1_ST	P35222	CTNNB1	Q13153	PAK1	S47	S45N	45	Missense	proximal	-2	no	18.676	21.234	EPSD	COSMIC	19.028	Gain
STE_STE20_PAKA_PAK1_ST	P35222	CTNNB1	Q13153	PAK1	S179	H176R	176	Missense	distal	-3	no	13.771	19.843	EPSD	COSMIC	19.028	Gain
STE_STE20_PAKA_PAK1_ST	P35222	CTNNB1	Q13153	PAK1	S179	Q177P	177	Missense	proximal	-2	no	13.771	19.454	EPSD	COSMIC	19.028	Gain
STE_STE20_PAKA_PAK1_ST	P35222	CTNNB1	Q13153	PAK1	S184	A187T	187	Missense	distal	3	no	20.045	18.799	EPSD	COSMIC	19.028	Loss
STE_STE20_PAKA_PAK1_ST	P35222	CTNNB1	Q13153	PAK1	S184	R190C	190	Missense	distal	6	no	20.045	20.681	EPSD	COSMIC	19.028	Up-regulation
STE_STE20_PAKA_PAK1_ST	P35222	CTNNB1	Q13153	PAK1	S184	A187D	187	Missense	distal	3	no	20.045	19.776	EPSD	COSMIC	19.028	Down-regulation
STE_STE20_PAKA_PAK1_ST	P35222	CTNNB1	Q13153	PAK1	S184	A183S	183	Missense	proximal	-1	no	20.045	22.596	EPSD	COSMIC	19.028	Up-regulation
STE_STE20_PAKA_PAK1_ST	P35222	CTNNB1	Q13153	PAK1	S184	Q177P	177	Missense	distal	-7	no	20.045	19.742	EPSD	COSMIC	19.028	Down-regulation
STE_STE20_PAKA_PAK1_ST	P35222	CTNNB1	Q13153	PAK1	S184	A183T	183	Missense	proximal	-1	no	20.045	23.075	EPSD	COSMIC	19.028	Up-regulation
STE_STE20_PAKA_PAK1_ST	P35222	CTNNB1	Q13153	PAK1	S184	I188M	188	Missense	distal	4	no	20.045	20.250	EPSD	COSMIC	19.028	Up-regulation
STE_STE20_PAKA_PAK1_ST	P35222	CTNNB1	Q13153	PAK1	S184	R190H	190	Missense	distal	6	no	20.045	20.489	EPSD	COSMIC	19.028	Up-regulation
STE_STE20_PAKA_PAK1_ST	P35222	CTNNB1	Q13153	PAK1	S184	A187V	187	Missense	distal	3	no	20.045	19.790	EPSD	COSMIC	19.028	Down-regulation
STE_STE20_PAKA_PAK1_ST	P35222	CTNNB1	Q13153	PAK1	S184	E182D	182	Missense	proximal	-2	no	20.045	20.230	EPSD	COSMIC	19.028	Up-regulation
STE_STE20_PAKA_PAK1_ST	P35222	CTNNB1	Q13153	PAK1	S184	R185K	185	Missense	proximal	1	no	20.045	19.688	EPSD	COSMIC	19.028	Down-regulation
STE_STE20_PAKA_PAK1_ST	P35222	CTNNB1	Q13153	PAK1	S191	I188M	188	Missense	distal	-3	no	11.410	19.307	EPSD	COSMIC	19.028	Gain
STE_STE20_PAKA_PAK1_ST	P35222	CTNNB1	Q13153	PAK1	T332	V325I	325	Missense	distal	-7	no	20.339	21.116	EPSD	COSMIC	19.028	Up-regulation
STE_STE20_PAKA_PAK1_ST	P35222	CTNNB1	Q13153	PAK1	T332	L336V	336	Missense	distal	4	no	20.339	21.165	EPSD	COSMIC	19.028	Up-regulation
STE_STE20_PAKA_PAK1_ST	P35222	CTNNB1	Q13153	PAK1	T332	I327T	327	Missense	distal	-5	no	20.339	20.344	EPSD	COSMIC	19.028	Up-regulation
STE_STE20_PAKA_PAK1_ST	P35222	CTNNB1	Q13153	PAK1	T332	I327V	327	Missense	distal	-5	no	20.339	20.419	EPSD	COSMIC	19.028	Up-regulation
STE_STE20_PAKA_PAK1_ST	P35222	CTNNB1	Q13153	PAK1	T332	K335R	335	Missense	distal	3	no	20.339	20.165	EPSD	COSMIC	19.028	Down-regulation
STE_STE20_PAKA_PAK1_ST	P35222	CTNNB1	Q13153	PAK1	T332	K335Q	335	Missense	distal	3	no	20.339	20.664	EPSD	COSMIC	19.028	Up-regulation
STE_STE20_PAKA_PAK1_ST	P35222	CTNNB1	Q13153	PAK1	T332	L337P	337	Missense	distal	5	no	20.339	20.354	EPSD	COSMIC	19.028	Up-regulation
STE_STE20_PAKA_PAK1_ST	P35222	CTNNB1	Q13153	PAK1	T551	Q558H	558	Missense	distal	7	no	19.015	19.066	EPSD	COSMIC	19.028	Gain
STE_STE20_PAKA_PAK1_ST	P35222	CTNNB1	Q13153	PAK1	T551	S552F	552	Missense	proximal	1	no	19.015	19.275	EPSD	COSMIC	19.028	Gain
STE_STE20_PAKA_PAK1_ST	P35222	CTNNB1	Q13153	PAK1	S552	T551K	551	Missense	proximal	-1	no	29.381	29.449	EPSD	COSMIC	19.028	Up-regulation
STE_STE20_PAKA_PAK1_ST	P35222	CTNNB1	Q13153	PAK1	S552	R549C	549	Missense	distal	-3	no	29.381	9.425	EPSD	COSMIC	19.028	Loss
STE_STE20_PAKA_PAK1_ST	P35222	CTNNB1	Q13153	PAK1	S552	Q545K	545	Missense	distal	-7	no	29.381	29.285	EPSD	COSMIC	19.028	Down-regulation
STE_STE20_PAKA_PAK1_ST	P35222	CTNNB1	Q13153	PAK1	S552	Q558H	558	Missense	distal	6	no	29.381	29.674	EPSD	COSMIC	19.028	Up-regulation
STE_STE20_PAKA_PAK1_ST	P35222	CTNNB1	Q13153	PAK1	S552	G555A	555	Missense	distal	3	no	29.381	28.350	EPSD	COSMIC	19.028	Down-regulation
STE_STE20_PAKA_PAK1_ST	P35222	CTNNB1	Q13153	PAK1	S552	R550H	550	Missense	proximal	-2	no	29.381	23.967	EPSD	COSMIC	19.028	Down-regulation
STE_STE20_PAKA_PAK1_ST	P35222	CTNNB1	Q13153	PAK1	S552	R550L	550	Missense	proximal	-2	no	29.381	20.817	EPSD	COSMIC	19.028	Down-regulation
STE_STE20_PAKA_PAK1_ST	P35222	CTNNB1	Q13153	PAK1	S552	D546E	546	Missense	distal	-6	no	29.381	30.278	EPSD	COSMIC	19.028	Up-regulation
STE_STE20_PAKA_PAK1_ST	P35222	CTNNB1	Q13153	PAK1	S552	S552F	552	Missense	central	0	yes	29.381	0.000	EPSD	COSMIC	19.028	Loss
STE_STE20_PAKA_PAK1_ST	P35222	CTNNB1	Q13153	PAK1	S552	T547S	547	Missense	distal	-5	no	29.381	28.953	EPSD	COSMIC	19.028	Down-regulation
STE_STE20_PAKA_PAK1_ST	P35222	CTNNB1	Q13153	PAK1	S552	G554D	554	Missense	proximal	2	no	29.381	28.570	EPSD	COSMIC	19.028	Down-regulation
STE_STE20_PAKA_PAK1_ST	P35222	CTNNB1	Q13153	PAK1	S552	R550Q	550	Missense	proximal	-2	no	29.381	20.174	EPSD	COSMIC	19.028	Down-regulation
STE_STE20_PAKA_PAK1_ST	P35222	CTNNB1	Q13153	PAK1	S552	T551I	551	Missense	proximal	-1	no	29.381	28.526	EPSD	COSMIC	19.028	Down-regulation
STE_STE20_PAKA_PAK1_ST	P35222	CTNNB1	Q13153	PAK1	S675	R673W	673	Missense	proximal	-2	no	27.663	14.725	PhosphoSitePlus	COSMIC	19.028	Loss
STE_STE20_PAKA_PAK1_ST	P35222	CTNNB1	Q13153	PAK1	S675	S680I	680	Missense	distal	5	no	27.663	27.670	PhosphoSitePlus	COSMIC	19.028	Up-regulation
STE_STE20_PAKA_PAK1_ST	P35222	CTNNB1	Q13153	PAK1	S675	E677D	677	Missense	proximal	2	no	27.663	27.973	PhosphoSitePlus	COSMIC	19.028	Up-regulation
STE_STE20_PAKA_PAK1_ST	P35222	CTNNB1	Q13153	PAK1	S675	R673H	673	Missense	proximal	-2	no	27.663	22.249	PhosphoSitePlus	COSMIC	19.028	Down-regulation
STE_STE20_PAKA_PAK1_ST	P35222	CTNNB1	Q13153	PAK1	S675	L678F	678	Missense	distal	3	no	27.663	26.450	PhosphoSitePlus	COSMIC	19.028	Down-regulation
STE_STE20_PAKA_PAK1_ST	P35222	CTNNB1	Q13153	PAK1	S675	R673C	673	Missense	proximal	-2	no	27.663	14.943	PhosphoSitePlus	COSMIC	19.028	Loss
STE_STE20_PAKA_PAK1_ST	P35222	CTNNB1	Q13153	PAK1	S718	S715R	715	Missense	distal	-3	no	15.260	23.931	EPSD	COSMIC	19.028	Gain
STE_STE20_PAKA_PAK1_ST	Q9Y6X9	MORC2	Q13153	PAK1	S268	R275K	275	Missense	distal	7	no	30.125	30.247	EPSD	COSMIC	19.028	Up-regulation
STE_STE20_PAKA_PAK1_ST	Q9Y6X9	MORC2	Q13153	PAK1	S281	R275K	275	Missense	distal	-6	no	19.770	17.713	EPSD	COSMIC	19.028	Loss
STE_STE20_PAKA_PAK1_ST	Q9Y6X9	MORC2	Q13153	PAK1	S281	Y277C	277	Missense	distal	-4	no	19.770	19.801	EPSD	COSMIC	19.028	Up-regulation
STE_STE20_PAKA_PAK1_ST	Q9Y6X9	MORC2	Q13153	PAK1	S281	R287H	287	Missense	distal	6	no	19.770	20.215	EPSD	COSMIC	19.028	Up-regulation
STE_STE20_PAKA_PAK1_ST	Q9Y6X9	MORC2	Q13153	PAK1	S281	R283H	283	Missense	proximal	2	no	19.770	20.090	EPSD	COSMIC	19.028	Up-regulation
STE_STE20_PAKA_PAK1_ST	Q9Y6X9	MORC2	Q13153	PAK1	S281	M276I	276	Missense	distal	-5	no	19.770	19.330	EPSD	COSMIC	19.028	Down-regulation
STE_STE20_PAKA_PAK1_ST	Q9Y6X9	MORC2	Q13153	PAK1	S281	R283S	283	Missense	proximal	2	no	19.770	20.156	EPSD	COSMIC	19.028	Up-regulation
STE_STE20_PAKA_PAK1_ST	Q9Y6X9	MORC2	Q13153	PAK1	S281	Y279C	279	Missense	proximal	-2	no	19.770	11.390	EPSD	COSMIC	19.028	Loss
STE_STE20_PAKA_PAK1_ST	Q9Y6X9	MORC2	Q13153	PAK1	T603	R608H	608	Missense	distal	5	no	25.375	25.387	EPSD	COSMIC	19.028	Up-regulation
STE_STE20_PAKA_PAK1_ST	Q9Y6X9	MORC2	Q13153	PAK1	T603	S602F	602	Missense	proximal	-1	no	25.375	26.172	EPSD	COSMIC	19.028	Up-regulation
STE_STE20_PAKA_PAK1_ST	Q9Y6X9	MORC2	Q13153	PAK1	S615	R608H	608	Missense	distal	-7	no	33.597	32.246	EPSD	COSMIC	19.028	Down-regulation
STE_STE20_PAKA_PAK1_ST	Q9Y6X9	MORC2	Q13153	PAK1	S615	P613S	613	Missense	proximal	-2	no	33.597	28.969	EPSD	COSMIC	19.028	Down-regulation
STE_STE20_PAKA_PAK1_ST	Q9Y6X9	MORC2	Q13153	PAK1	S615	P613H	613	Missense	proximal	-2	no	33.597	31.708	EPSD	COSMIC	19.028	Down-regulation
STE_STE20_PAKA_PAK1_ST	Q9Y6X9	MORC2	Q13153	PAK1	S615	I622T	622	Missense	distal	7	no	33.597	33.296	EPSD	COSMIC	19.028	Down-regulation
STE_STE20_PAKA_PAK1_ST	Q9Y6X9	MORC2	Q13153	PAK1	S615	P616T	616	Missense	proximal	1	no	33.597	34.123	EPSD	COSMIC	19.028	Up-regulation
STE_STE20_PAKA_PAK1_ST	Q9Y6X9	MORC2	Q13153	PAK1	S615	R612H	612	Missense	distal	-3	no	33.597	27.526	EPSD	COSMIC	19.028	Down-regulation
STE_STE20_PAKA_PAK1_ST	Q9Y6X9	MORC2	Q13153	PAK1	S631	L632M	632	Missense	proximal	1	no	24.224	24.062	EPSD	COSMIC	19.028	Down-regulation
STE_STE20_PAKA_PAK1_ST	Q9Y6X9	MORC2	Q13153	PAK1	S631	P635R	635	Missense	distal	4	no	24.224	21.270	EPSD	COSMIC	19.028	Down-regulation
STE_STE20_PAKA_PAK1_ST	Q9Y6X9	MORC2	Q13153	PAK1	S631	P635S	635	Missense	distal	4	no	24.224	21.874	EPSD	COSMIC	19.028	Down-regulation
STE_STE20_PAKA_PAK1_ST	Q9Y6X9	MORC2	Q13153	PAK1	S631	A625T	625	Missense	distal	-6	no	24.224	24.151	EPSD	COSMIC;CCLE	19.028	Down-regulation
STE_STE20_PAKA_PAK1_ST	Q9Y6X9	MORC2	Q13153	PAK1	S631	P635L	635	Missense	distal	4	no	24.224	22.667	EPSD	COSMIC	19.028	Down-regulation
STE_STE20_PAKA_PAK1_ST	Q9Y6X9	MORC2	Q13153	PAK1	S631	P637S	637	Missense	distal	6	no	24.224	23.976	EPSD	COSMIC	19.028	Down-regulation
STE_STE20_PAKA_PAK1_ST	Q9Y6X9	MORC2	Q13153	PAK1	S639	P645S	645	Missense	distal	6	no	19.336	19.088	EPSD	COSMIC	19.028	Down-regulation
STE_STE20_PAKA_PAK1_ST	Q9Y6X9	MORC2	Q13153	PAK1	S639	L632M	632	Missense	distal	-7	no	19.336	18.406	EPSD	COSMIC	19.028	Loss
STE_STE20_PAKA_PAK1_ST	Q9Y6X9	MORC2	Q13153	PAK1	S639	P635R	635	Missense	distal	-4	no	19.336	19.855	EPSD	COSMIC	19.028	Up-regulation
STE_STE20_PAKA_PAK1_ST	Q9Y6X9	MORC2	Q13153	PAK1	S639	P635S	635	Missense	distal	-4	no	19.336	19.388	EPSD	COSMIC	19.028	Up-regulation
STE_STE20_PAKA_PAK1_ST	Q9Y6X9	MORC2	Q13153	PAK1	S639	P635L	635	Missense	distal	-4	no	19.336	19.542	EPSD	COSMIC	19.028	Up-regulation
STE_STE20_PAKA_PAK1_ST	Q9Y6X9	MORC2	Q13153	PAK1	S639	P637S	637	Missense	proximal	-2	no	19.336	14.708	EPSD	COSMIC	19.028	Loss
STE_STE20_PAKA_PAK1_ST	Q9Y6X9	MORC2	Q13153	PAK1	S639	P641L	641	Missense	proximal	2	no	19.336	19.504	EPSD	COSMIC	19.028	Up-regulation
STE_STE20_PAKA_PAK1_ST	Q9Y6X9	MORC2	Q13153	PAK1	S648	P645S	645	Missense	distal	-3	no	21.222	18.233	EPSD	COSMIC	19.028	Loss
STE_STE20_PAKA_PAK1_ST	Q9Y6X9	MORC2	Q13153	PAK1	S648	P641L	641	Missense	distal	-7	no	21.222	20.776	EPSD	COSMIC	19.028	Down-regulation
STE_STE20_PAKA_PAK1_ST	Q9Y6X9	MORC2	Q13153	PAK1	T684	K683R	683	Missense	proximal	-1	no	19.910	20.444	EPSD	COSMIC	19.028	Up-regulation
STE_STE20_PAKA_PAK1_ST	Q9Y6X9	MORC2	Q13153	PAK1	S686	K683R	683	Missense	distal	-3	no	22.720	23.907	EPSD	COSMIC	19.028	Up-regulation
STE_STE20_PAKA_PAK1_ST	Q9Y6X9	MORC2	Q13153	PAK1	S725	P731L	731	Missense	distal	6	no	22.319	22.343	EPSD	COSMIC	19.028	Up-regulation
STE_STE20_PAKA_PAK1_ST	Q9Y6X9	MORC2	Q13153	PAK1	S725	I727F	727	Missense	proximal	2	no	22.319	22.254	EPSD	COSMIC	19.028	Down-regulation
STE_STE20_PAKA_PAK1_ST	Q9Y6X9	MORC2	Q13153	PAK1	S725	P718L	718	Missense	distal	-7	no	22.319	21.873	EPSD	COSMIC	19.028	Down-regulation
STE_STE20_PAKA_PAK1_ST	Q9Y6X9	MORC2	Q13153	PAK1	S730	I727F	727	Missense	distal	-3	no	10.927	21.234	EPSD	COSMIC	19.028	Gain
STE_STE20_PAKA_PAK1_ST	Q9Y6X9	MORC2	Q13153	PAK1	S739	R736W	736	Missense	distal	-3	no	28.363	20.802	PhosphoSitePlus	COSMIC	19.028	Down-regulation
STE_STE20_PAKA_PAK1_ST	Q9Y6X9	MORC2	Q13153	PAK1	S739	S743F	743	Missense	distal	4	no	28.363	29.827	PhosphoSitePlus	COSMIC	19.028	Up-regulation
STE_STE20_PAKA_PAK1_ST	Q9Y6X9	MORC2	Q13153	PAK1	S739	P734T	734	Missense	distal	-5	no	28.363	27.929	PhosphoSitePlus	COSMIC	19.028	Down-regulation
STE_STE20_PAKA_PAK1_ST	Q9Y6X9	MORC2	Q13153	PAK1	S856	D863H	863	Missense	distal	7	no	21.359	21.325	EPSD	COSMIC	19.028	Down-regulation
STE_STE20_PAKA_PAK1_ST	Q9Y6X9	MORC2	Q13153	PAK1	S856	D863N	863	Missense	distal	7	no	21.359	21.355	EPSD	COSMIC	19.028	Down-regulation
STE_STE20_PAKA_PAK1_ST	Q9Y6X9	MORC2	Q13153	PAK1	S856	L862V	862	Missense	distal	6	no	21.359	21.424	EPSD	COSMIC	19.028	Up-regulation
STE_STE20_PAKA_PAK1_ST	Q9Y6X9	MORC2	Q13153	PAK1	S856	P857Q	857	Missense	proximal	1	no	21.359	21.542	EPSD	COSMIC	19.028	Up-regulation
STE_STE20_PAKA_PAK1_ST	Q9Y6X9	MORC2	Q13153	PAK1	S856	P855H	855	Missense	proximal	-1	no	21.359	22.876	EPSD	COSMIC	19.028	Up-regulation
STE_STE20_PAKA_PAK1_ST	Q9Y6X9	MORC2	Q13153	PAK1	S930	P925Q	925	Missense	distal	-5	no	19.858	19.065	EPSD	COSMIC	19.028	Down-regulation
STE_STE20_PAKA_PAK1_ST	Q9Y6X9	MORC2	Q13153	PAK1	S930	S930F	930	Missense	central	0	yes	19.858	0.000	EPSD	COSMIC	19.028	Loss
STE_STE20_PAKA_PAK1_ST	Q9Y6X9	MORC2	Q13153	PAK1	S983	K986E	986	Missense	distal	3	no	19.890	19.789	EPSD	COSMIC	19.028	Down-regulation
STE_STE20_PAKA_PAK1_ST	Q9Y6X9	MORC2	Q13153	PAK1	S983	E989K	989	Missense	distal	6	no	19.890	20.204	EPSD	COSMIC	19.028	Up-regulation
STE_STE20_PAKA_PAK1_ST	Q9Y6X9	MORC2	Q13153	PAK1	S983	R981C	981	Missense	proximal	-2	no	19.890	7.169	EPSD	COSMIC	19.028	Loss
STE_STE20_PAKA_PAK1_ST	Q9Y6X9	MORC2	Q13153	PAK1	S983	E984D	984	Missense	proximal	1	no	19.890	19.815	EPSD	COSMIC	19.028	Down-regulation
STE_STE20_PAKA_PAK1_ST	Q9Y6X9	MORC2	Q13153	PAK1	S983	E978K	978	Missense	distal	-5	no	19.890	19.950	EPSD	COSMIC	19.028	Up-regulation
STE_STE20_PAKA_PAK1_ST	Q9Y6X9	MORC2	Q13153	PAK1	S983	E984G	984	Missense	proximal	1	no	19.890	19.635	EPSD	COSMIC	19.028	Down-regulation
STE_STE20_PAKA_PAK1_ST	Q9Y6X9	MORC2	Q13153	PAK1	S983	R981H	981	Missense	proximal	-2	no	19.890	14.476	EPSD	COSMIC	19.028	Loss
STE_STE20_PAKA_PAK1_ST	Q14247	CTTN	Q13153	PAK1	S155	Y154C	154	Missense	proximal	-1	no	21.265	19.006	EPSD	COSMIC;CCLE	19.028	Loss
STE_STE20_PAKA_PAK1_ST	Q14247	CTTN	Q13153	PAK1	S156	Y154C	154	Missense	proximal	-2	no	20.434	12.054	EPSD	COSMIC;CCLE	19.028	Loss
STE_STE20_PAKA_PAK1_ST	Q14247	CTTN	Q13153	PAK1	S187	D190N	190	Missense	distal	3	no	20.831	21.109	EPSD	COSMIC	19.028	Up-regulation
STE_STE20_PAKA_PAK1_ST	Q14247	CTTN	Q13153	PAK1	S192	D190N	190	Missense	proximal	-2	no	22.007	22.748	EPSD	COSMIC	19.028	Up-regulation
STE_STE20_PAKA_PAK1_ST	Q14247	CTTN	Q13153	PAK1	S224	S224F	224	Missense	central	0	yes	20.281	0.000	EPSD	COSMIC	19.028	Loss
STE_STE20_PAKA_PAK1_ST	Q14247	CTTN	Q13153	PAK1	T267	G274E	274	Missense	distal	7	no	20.260	20.160	EPSD	COSMIC	19.028	Down-regulation
STE_STE20_PAKA_PAK1_ST	Q14247	CTTN	Q13153	PAK1	T267	S261F	261	Missense	distal	-6	no	20.260	19.493	EPSD	COSMIC	19.028	Down-regulation
STE_STE20_PAKA_PAK1_ST	Q14247	CTTN	Q13153	PAK1	T267	G274W	274	Missense	distal	7	no	20.260	20.274	EPSD	COSMIC	19.028	Up-regulation
STE_STE20_PAKA_PAK1_ST	Q14247	CTTN	Q13153	PAK1	T267	G274A	274	Missense	distal	7	no	20.260	20.206	EPSD	COSMIC	19.028	Down-regulation
STE_STE20_PAKA_PAK1_ST	Q14247	CTTN	Q13153	PAK1	T267	G270E	270	Missense	distal	3	no	20.260	17.747	EPSD	COSMIC;CCLE	19.028	Loss
STE_STE20_PAKA_PAK1_ST	Q14247	CTTN	Q13153	PAK1	S332	E325D	325	Missense	distal	-7	no	21.033	20.093	EPSD	COSMIC	19.028	Down-regulation
STE_STE20_PAKA_PAK1_ST	Q14247	CTTN	Q13153	PAK1	S332	V330E	330	Missense	proximal	-2	no	21.033	20.072	EPSD	COSMIC	19.028	Down-regulation
STE_STE20_PAKA_PAK1_ST	Q14247	CTTN	Q13153	PAK1	S332	T328A	328	Missense	distal	-4	no	21.033	20.616	EPSD	COSMIC	19.028	Down-regulation
STE_STE20_PAKA_PAK1_ST	Q14247	CTTN	Q13153	PAK1	T399	Q394K	394	Missense	distal	-5	no	20.621	20.669	EPSD	COSMIC	19.028	Up-regulation
STE_STE20_PAKA_PAK1_ST	Q14247	CTTN	Q13153	PAK1	T399	R396T	396	Missense	distal	-3	no	20.621	14.364	EPSD	COSMIC	19.028	Loss
STE_STE20_PAKA_PAK1_ST	Q14247	CTTN	Q13153	PAK1	T401	Q394K	394	Missense	distal	-7	no	19.925	19.829	EPSD	COSMIC	19.028	Down-regulation
STE_STE20_PAKA_PAK1_ST	Q14247	CTTN	Q13153	PAK1	T401	R396T	396	Missense	distal	-5	no	19.925	20.383	EPSD	COSMIC	19.028	Up-regulation
STE_STE20_PAKA_PAK1_ST	Q14247	CTTN	Q13153	PAK1	S405	T411I	411	Missense	distal	6	no	19.139	19.629	EPSD;PhosphoSitePlus	COSMIC	19.028	Up-regulation
STE_STE20_PAKA_PAK1_ST	Q14247	CTTN	Q13153	PAK1	S417	T411I	411	Missense	distal	-6	no	21.187	19.139	EPSD	COSMIC	19.028	Down-regulation
STE_STE20_PAKA_PAK1_ST	Q14247	CTTN	Q13153	PAK1	S417	V420I	420	Missense	distal	3	no	21.187	21.268	EPSD	COSMIC	19.028	Up-regulation
STE_STE20_PAKA_PAK1_ST	Q14247	CTTN	Q13153	PAK1	S418	T411I	411	Missense	distal	-7	no	22.486	21.689	EPSD;PhosphoSitePlus	COSMIC	19.028	Down-regulation
STE_STE20_PAKA_PAK1_ST	Q14247	CTTN	Q13153	PAK1	S418	V420I	420	Missense	proximal	2	no	22.486	21.661	EPSD;PhosphoSitePlus	COSMIC	19.028	Down-regulation
STE_STE20_PAKA_PAK1_ST	P49023	PXN	Q13153	PAK1	S119	F120S	120	Missense	proximal	1	no	19.848	19.587	EPSD	COSMIC	19.028	Down-regulation
STE_STE20_PAKA_PAK1_ST	P49023	PXN	Q13153	PAK1	S119	S126P	126	Missense	distal	7	no	19.848	19.923	EPSD	COSMIC	19.028	Up-regulation
STE_STE20_PAKA_PAK1_ST	P49023	PXN	Q13153	PAK1	S170	D165Y	165	Missense	distal	-5	no	20.254	20.428	EPSD	COSMIC	19.028	Up-regulation
STE_STE20_PAKA_PAK1_ST	P49023	PXN	Q13153	PAK1	S170	G175W	175	Missense	distal	5	no	20.254	20.253	EPSD	COSMIC	19.028	Down-regulation
STE_STE20_PAKA_PAK1_ST	P49023	PXN	Q13153	PAK1	S170	P163L	163	Missense	distal	-7	no	20.254	19.808	EPSD	COSMIC	19.028	Down-regulation
STE_STE20_PAKA_PAK1_ST	P49023	PXN	Q13153	PAK1	S170	P172L	172	Missense	proximal	2	no	20.254	20.422	EPSD	COSMIC	19.028	Up-regulation
STE_STE20_PAKA_PAK1_ST	P49023	PXN	Q13153	PAK1	S170	P171S	171	Missense	proximal	1	no	20.254	20.370	EPSD	COSMIC	19.028	Up-regulation
STE_STE20_PAKA_PAK1_ST	P49023	PXN	Q13153	PAK1	S170	N168I	168	Missense	proximal	-2	no	20.254	19.564	EPSD	COSMIC;GDSC	19.028	Down-regulation
STE_STE20_PAKA_PAK1_ST	P49023	PXN	Q13153	PAK1	S230	P229L	229	Missense	proximal	-1	no	15.065	19.257	EPSD	COSMIC	19.028	Gain
STE_STE20_PAKA_PAK1_ST	P49023	PXN	Q13153	PAK1	S250	R256H	256	Missense	distal	6	no	21.313	21.757	EPSD	COSMIC	19.028	Up-regulation
STE_STE20_PAKA_PAK1_ST	P49023	PXN	Q13153	PAK1	S258	R256H	256	Missense	proximal	-2	no	22.799	17.385	PhosphoSitePlus;EPSD	COSMIC	19.028	Loss
STE_STE20_PAKA_PAK1_ST	P49023	PXN	Q13153	PAK1	S302	G300R	300	Missense	proximal	-2	no	13.534	23.098	EPSD	COSMIC	19.028	Gain
STE_STE20_PAKA_PAK1_ST	P49023	PXN	Q13153	PAK1	S303	P304L	304	Missense	proximal	1	no	23.384	23.671	EPSD	COSMIC	19.028	Up-regulation
STE_STE20_PAKA_PAK1_ST	P49023	PXN	Q13153	PAK1	S303	P304R	304	Missense	proximal	1	no	23.384	23.903	EPSD	COSMIC	19.028	Up-regulation
STE_STE20_PAKA_PAK1_ST	P49023	PXN	Q13153	PAK1	S303	G300R	300	Missense	distal	-3	no	23.384	31.261	EPSD	COSMIC	19.028	Up-regulation
STE_STE20_PAKA_PAK1_ST	P49023	PXN	Q13153	PAK1	S303	E309K	309	Missense	distal	6	no	23.384	23.699	EPSD	COSMIC	19.028	Up-regulation
STE_STE20_PAKA_PAK1_ST	P49023	PXN	Q13153	PAK1	S303	D298Y	298	Missense	distal	-5	no	23.384	23.559	EPSD	COSMIC	19.028	Up-regulation
STE_STE20_PAKA_PAK1_ST	P49023	PXN	Q13153	PAK1	S303	S303R	303	Missense	central	0	yes	23.384	0.000	EPSD	COSMIC	19.028	Loss
STE_STE20_PAKA_PAK1_ST	P49023	PXN	Q13153	PAK1	S303	G306R	306	Missense	distal	3	no	23.384	20.798	EPSD	COSMIC	19.028	Down-regulation
STE_STE20_PAKA_PAK1_ST	P49023	PXN	Q13153	PAK1	S303	R301Q	301	Missense	proximal	-2	no	23.384	14.177	EPSD	COSMIC	19.028	Loss
STE_STE20_PAKA_PAK1_ST	P49023	PXN	Q13153	PAK1	S303	G299S	299	Missense	distal	-4	no	23.384	23.804	EPSD	COSMIC	19.028	Up-regulation
STE_STE20_PAKA_PAK1_ST	P49023	PXN	Q13153	PAK1	S320	S322A	322	Missense	proximal	2	no	18.941	19.845	EPSD	COSMIC	19.028	Gain
STE_STE20_PAKA_PAK1_ST	P49023	PXN	Q13153	PAK1	S533	S536Y	536	Missense	distal	3	no	22.668	26.447	EPSD	COSMIC	19.028	Up-regulation
STE_STE20_PAKA_PAK1_ST	P49023	PXN	Q13153	PAK1	S533	H526Y	526	Missense	distal	-7	no	22.668	21.939	EPSD	COSMIC	19.028	Down-regulation
STE_STE20_PAKA_PAK1_ST	P49023	PXN	Q13153	PAK1	S533	C538R	538	Missense	distal	5	no	22.668	22.645	EPSD	COSMIC	19.028	Down-regulation
STE_STE20_PAKA_PAK1_ST	P49023	PXN	Q13153	PAK1	S533	E529K	529	Missense	distal	-4	no	22.668	22.747	EPSD	COSMIC	19.028	Up-regulation
STE_STE20_PAKA_PAK1_ST	P49023	PXN	Q13153	PAK1	S533	S533L	533	Missense	central	0	yes	22.668	0.000	EPSD	COSMIC	19.028	Loss
STE_STE20_PAKA_PAK1_ST	P49023	PXN	Q13153	PAK1	T543	S536Y	536	Missense	distal	-7	no	21.655	20.145	EPSD	COSMIC	19.028	Down-regulation
STE_STE20_PAKA_PAK1_ST	P49023	PXN	Q13153	PAK1	T543	C538R	538	Missense	distal	-5	no	21.655	20.900	EPSD	COSMIC	19.028	Down-regulation
STE_STE20_PAKA_PAK1_ST	P49023	PXN	Q13153	PAK1	T543	A549V	549	Missense	distal	6	no	21.655	21.976	EPSD	COSMIC	19.028	Up-regulation
STE_STE20_PAKA_PAK1_ST	P49023	PXN	Q13153	PAK1	T543	R545L	545	Missense	proximal	2	no	21.655	22.854	EPSD	COSMIC	19.028	Up-regulation
STE_STE20_PAKA_PAK1_ST	Q9Y2X7	GIT1	Q13153	PAK1	S134	A130T	130	Missense	distal	-4	no	19.817	20.233	EPSD	COSMIC	19.028	Up-regulation
STE_STE20_PAKA_PAK1_ST	Q9Y2X7	GIT1	Q13153	PAK1	S134	T129I	129	Missense	distal	-5	no	19.817	19.811	EPSD	COSMIC	19.028	Down-regulation
STE_STE20_PAKA_PAK1_ST	Q9Y2X7	GIT1	Q13153	PAK1	S134	K135R	135	Missense	proximal	1	no	19.817	20.173	EPSD	COSMIC	19.028	Up-regulation
STE_STE20_PAKA_PAK1_ST	Q9Y2X7	GIT1	Q13153	PAK1	S361	D365V	365	Missense	distal	4	no	23.656	24.525	EPSD	COSMIC	19.028	Up-regulation
STE_STE20_PAKA_PAK1_ST	Q9Y2X7	GIT1	Q13153	PAK1	S375	Q374H	374	Missense	proximal	-1	no	20.414	19.325	EPSD	COSMIC	19.028	Down-regulation
STE_STE20_PAKA_PAK1_ST	Q9Y2X7	GIT1	Q13153	PAK1	S410	R409Q	409	Missense	proximal	-1	no	20.629	18.910	EPSD	COSMIC	19.028	Loss
STE_STE20_PAKA_PAK1_ST	Q9Y2X7	GIT1	Q13153	PAK1	S410	R407Q	407	Missense	distal	-3	no	20.629	11.904	EPSD	COSMIC	19.028	Loss
STE_STE20_PAKA_PAK1_ST	Q9Y2X7	GIT1	Q13153	PAK1	S508	P512L	512	Missense	distal	4	no	21.055	19.498	PhosphoSitePlus;EPSD	COSMIC	19.028	Down-regulation
STE_STE20_PAKA_PAK1_ST	Q9Y2X7	GIT1	Q13153	PAK1	S546	V547L	547	Missense	proximal	1	no	18.924	19.171	EPSD	COSMIC	19.028	Gain
STE_STE20_PAKA_PAK1_ST	Q9Y2X7	GIT1	Q13153	PAK1	S571	F567L	567	Missense	distal	-4	no	19.364	19.236	EPSD	COSMIC	19.028	Down-regulation
STE_STE20_PAKA_PAK1_ST	Q9Y2X7	GIT1	Q13153	PAK1	S585	R582H	582	Missense	distal	-3	no	22.971	16.900	EPSD	COSMIC	19.028	Loss
STE_STE20_PAKA_PAK1_ST	Q9Y2X7	GIT1	Q13153	PAK1	S588	D595N	595	Missense	distal	7	no	20.441	20.437	EPSD	COSMIC	19.028	Down-regulation
STE_STE20_PAKA_PAK1_ST	Q9Y2X7	GIT1	Q13153	PAK1	S588	R582H	582	Missense	distal	-6	no	20.441	19.582	EPSD	COSMIC	19.028	Down-regulation
STE_STE20_PAKA_PAK1_ST	Q9Y2X7	GIT1	Q13153	PAK1	S592	D595N	595	Missense	distal	3	no	21.563	21.841	EPSD	COSMIC	19.028	Up-regulation
STE_STE20_PAKA_PAK1_ST	Q9Y2X7	GIT1	Q13153	PAK1	S592	Y598H	598	Missense	distal	6	no	21.563	21.099	EPSD	COSMIC	19.028	Down-regulation
STE_STE20_PAKA_PAK1_ST	Q9Y2X7	GIT1	Q13153	PAK1	S700	R703Q	703	Missense	distal	3	no	21.820	22.319	EPSD;PhosphoSitePlus	COSMIC	19.028	Up-regulation
STE_STE20_PAKA_PAK1_ST	P53350	PLK1	Q13153	PAK1	S49	S49N	49	Missense	central	0	yes	21.077	0.000	PhosphoSitePlus	COSMIC	19.028	Loss
STE_STE20_PAKA_PAK1_ST	P53350	PLK1	Q13153	PAK1	T210	G205V	205	Missense	distal	-5	no	21.693	21.281	EPSD	COSMIC	19.028	Down-regulation
STE_STE20_PAKA_PAK1_ST	P53350	PLK1	Q13153	PAK1	S326	A328T	328	Missense	proximal	2	no	24.459	22.816	EPSD	COSMIC	19.028	Down-regulation
STE_STE20_PAKA_PAK1_ST	P53350	PLK1	Q13153	PAK1	T341	L347F	347	Missense	distal	6	no	23.847	23.951	EPSD	COSMIC	19.028	Up-regulation
STE_STE20_PAKA_PAK1_ST	P53350	PLK1	Q13153	PAK1	T341	R337Q	337	Missense	distal	-4	no	23.847	23.378	EPSD	COSMIC	19.028	Down-regulation
STE_STE20_PAKA_PAK1_ST	P53350	PLK1	Q13153	PAK1	T341	S335R	335	Missense	distal	-6	no	23.847	25.857	EPSD	COSMIC;GDSC;CCLE	19.028	Up-regulation
STE_STE20_PAKA_PAK1_ST	P53350	PLK1	Q13153	PAK1	T459	S461Y	461	Missense	proximal	2	no	20.475	22.726	EPSD	COSMIC	19.028	Up-regulation
STE_STE20_PAKA_PAK1_ST	P53350	PLK1	Q13153	PAK1	T459	G458S	458	Missense	proximal	-1	no	20.475	23.462	EPSD	COSMIC	19.028	Up-regulation
STE_STE20_PAKA_PAK1_ST	P53350	PLK1	Q13153	PAK1	T459	S461F	461	Missense	proximal	2	no	20.475	20.558	EPSD	COSMIC	19.028	Up-regulation
STE_STE20_PAKA_PAK1_ST	P53350	PLK1	Q13153	PAK1	S565	E569G	569	Missense	distal	4	no	24.734	25.691	EPSD	COSMIC	19.028	Up-regulation
STE_STE20_PAKA_PAK1_ST	Q13352	ITGB3BP	Q13153	PAK1	S21	P20S	20	Missense	proximal	-1	no	16.726	19.969	EPSD	COSMIC	19.028	Gain
STE_STE20_PAKA_PAK1_ST	Q13352	ITGB3BP	Q13153	PAK1	S28	S28N	28	Missense	central	0	yes	23.887	0.000	PhosphoSitePlus	COSMIC	19.028	Loss
STE_STE20_PAKA_PAK1_ST	Q13352	ITGB3BP	Q13153	PAK1	S28	P34Q	34	Missense	distal	6	no	23.887	23.525	PhosphoSitePlus	COSMIC	19.028	Down-regulation
STE_STE20_PAKA_PAK1_ST	Q13352	ITGB3BP	Q13153	PAK1	S28	K22N	22	Missense	distal	-6	no	23.887	24.308	PhosphoSitePlus	COSMIC	19.028	Up-regulation
STE_STE20_PAKA_PAK1_ST	Q13352	ITGB3BP	Q13153	PAK1	S28	S33T	33	Missense	distal	5	no	23.887	23.888	PhosphoSitePlus	COSMIC	19.028	Up-regulation
STE_STE20_PAKA_PAK1_ST	Q13352	ITGB3BP	Q13153	PAK1	S50	P47R	47	Missense	distal	-3	no	19.063	24.746	EPSD	COSMIC	19.028	Up-regulation
STE_STE20_PAKA_PAK1_ST	Q13352	ITGB3BP	Q13153	PAK1	S50	A45V	45	Missense	distal	-5	no	19.063	18.939	EPSD	COSMIC	19.028	Loss
STE_STE20_PAKA_PAK1_ST	P24844	MYL9	Q13153	PAK1	S20	N21T	21	Missense	proximal	1	no	23.883	24.200	PhosphoSitePlus	COSMIC	19.028	Up-regulation
STE_STE20_PAKA_PAK1_ST	P24844	MYL9	Q13153	PAK1	S20	P15S	15	Missense	distal	-5	no	23.883	23.021	PhosphoSitePlus	COSMIC	19.028	Down-regulation
STE_STE20_PAKA_PAK1_ST	P24844	MYL9	Q13153	PAK1	S20	R14Q	14	Missense	distal	-6	no	23.883	22.621	PhosphoSitePlus	COSMIC	19.028	Down-regulation
STE_STE20_PAKA_PAK1_ST	P24844	MYL9	Q13153	PAK1	T135	M130I	130	Missense	distal	-5	no	20.439	19.998	EPSD	COSMIC	19.028	Down-regulation
STE_STE20_PAKA_PAK1_ST	P21333	FLNA	Q13153	PAK1	S204	C210R	210	Missense	distal	6	no	19.434	18.799	EPSD	COSMIC	19.028	Loss
STE_STE20_PAKA_PAK1_ST	P21333	FLNA	Q13153	PAK1	T341	D337N	337	Missense	distal	-4	no	19.929	19.418	EPSD	COSMIC	19.028	Down-regulation
STE_STE20_PAKA_PAK1_ST	P21333	FLNA	Q13153	PAK1	T341	N339H	339	Missense	proximal	-2	no	19.929	20.109	EPSD	COSMIC	19.028	Up-regulation
STE_STE20_PAKA_PAK1_ST	P21333	FLNA	Q13153	PAK1	T341	A334T	334	Missense	distal	-7	no	19.929	20.072	EPSD	COSMIC	19.028	Up-regulation
STE_STE20_PAKA_PAK1_ST	P21333	FLNA	Q13153	PAK1	S343	D337N	337	Missense	distal	-6	no	28.456	28.619	EPSD	COSMIC	19.028	Up-regulation
STE_STE20_PAKA_PAK1_ST	P21333	FLNA	Q13153	PAK1	S343	N339H	339	Missense	distal	-4	no	28.456	28.939	EPSD	COSMIC	19.028	Up-regulation
STE_STE20_PAKA_PAK1_ST	P21333	FLNA	Q13153	PAK1	S343	V350L	350	Missense	distal	7	no	28.456	28.487	EPSD	COSMIC	19.028	Up-regulation
STE_STE20_PAKA_PAK1_ST	P21333	FLNA	Q13153	PAK1	T572	E567G	567	Missense	distal	-5	no	19.568	20.427	EPSD	COSMIC	19.028	Up-regulation
STE_STE20_PAKA_PAK1_ST	P21333	FLNA	Q13153	PAK1	T572	V579M	579	Missense	distal	7	no	19.568	19.699	EPSD	COSMIC	19.028	Up-regulation
STE_STE20_PAKA_PAK1_ST	P21333	FLNA	Q13153	PAK1	S962	S959R	959	Missense	distal	-3	no	13.802	22.474	EPSD	COSMIC	19.028	Gain
STE_STE20_PAKA_PAK1_ST	P21333	FLNA	Q13153	PAK1	T1305	D1311G	1311	Missense	distal	6	no	19.455	19.778	EPSD	COSMIC;GDSC;CCLE	19.028	Up-regulation
STE_STE20_PAKA_PAK1_ST	P21333	FLNA	Q13153	PAK1	T1305	P1300H	1300	Missense	distal	-5	no	19.455	19.010	EPSD	COSMIC;GDSC;CCLE	19.028	Loss
STE_STE20_PAKA_PAK1_ST	P21333	FLNA	Q13153	PAK1	T1305	P1300L	1300	Missense	distal	-5	no	19.455	19.353	EPSD	COSMIC	19.028	Down-regulation
STE_STE20_PAKA_PAK1_ST	P21333	FLNA	Q13153	PAK1	S1812	G1806V	1806	Missense	distal	-6	no	22.366	22.923	EPSD	COSMIC	19.028	Up-regulation
STE_STE20_PAKA_PAK1_ST	P21333	FLNA	Q13153	PAK1	S1812	T1805I	1805	Missense	distal	-7	no	22.366	21.570	EPSD	COSMIC	19.028	Down-regulation
STE_STE20_PAKA_PAK1_ST	P21333	FLNA	Q13153	PAK1	S1961	A1968P	1968	Missense	distal	7	no	19.051	19.105	EPSD	COSMIC	19.028	Up-regulation
STE_STE20_PAKA_PAK1_ST	P21333	FLNA	Q13153	PAK1	S1961	S1961F	1961	Missense	central	0	yes	19.051	0.000	EPSD	COSMIC	19.028	Loss
STE_STE20_PAKA_PAK1_ST	P21333	FLNA	Q13153	PAK1	S1961	V1965I	1965	Missense	distal	4	no	19.051	18.949	EPSD	COSMIC	19.028	Loss
STE_STE20_PAKA_PAK1_ST	P21333	FLNA	Q13153	PAK1	S1967	A1968P	1968	Missense	proximal	1	no	21.788	21.757	EPSD	COSMIC	19.028	Down-regulation
STE_STE20_PAKA_PAK1_ST	P21333	FLNA	Q13153	PAK1	S1967	S1961F	1961	Missense	distal	-6	no	21.788	21.022	EPSD	COSMIC	19.028	Down-regulation
STE_STE20_PAKA_PAK1_ST	P21333	FLNA	Q13153	PAK1	S1967	V1965I	1965	Missense	proximal	-2	no	21.788	21.063	EPSD	COSMIC	19.028	Down-regulation
STE_STE20_PAKA_PAK1_ST	P21333	FLNA	Q13153	PAK1	S2152	R2149Q	2149	Missense	distal	-3	no	22.847	14.123	PhosphoSitePlus;EPSD	COSMIC	19.028	Loss
STE_STE20_PAKA_PAK1_ST	P21333	FLNA	Q13153	PAK1	S2152	P2151S	2151	Missense	proximal	-1	no	22.847	26.091	PhosphoSitePlus;EPSD	COSMIC	19.028	Up-regulation
STE_STE20_PAKA_PAK1_ST	P21333	FLNA	Q13153	PAK1	S2152	V2156I	2156	Missense	distal	4	no	22.847	22.745	PhosphoSitePlus;EPSD	COSMIC	19.028	Down-regulation
STE_STE20_PAKA_PAK1_ST	P21333	FLNA	Q13153	PAK1	S2152	R2149W	2149	Missense	distal	-3	no	22.847	15.287	PhosphoSitePlus;EPSD	COSMIC	19.028	Loss
STE_STE20_PAKA_PAK1_ST	P21333	FLNA	Q13153	PAK1	S2152	V2153A	2153	Missense	proximal	1	no	22.847	22.839	PhosphoSitePlus;EPSD	COSMIC	19.028	Down-regulation
STE_STE20_PAKA_PAK1_ST	P21333	FLNA	Q13153	PAK1	S2260	R2264L	2264	Missense	distal	4	no	19.181	20.578	EPSD	COSMIC	19.028	Up-regulation
STE_STE20_PAKA_PAK1_ST	P21333	FLNA	Q13153	PAK1	S2260	P2256S	2256	Missense	distal	-4	no	19.181	19.234	EPSD	COSMIC	19.028	Up-regulation
STE_STE20_PAKA_PAK1_ST	P21333	FLNA	Q13153	PAK1	S2260	F2259L	2259	Missense	proximal	-1	no	19.181	19.332	EPSD	COSMIC	19.028	Up-regulation
STE_STE20_PAKA_PAK1_ST	P21333	FLNA	Q13153	PAK1	S2260	E2265G	2265	Missense	distal	5	no	19.181	19.210	EPSD	COSMIC	19.028	Up-regulation
STE_STE20_PAKA_PAK1_ST	P21333	FLNA	Q13153	PAK1	S2292	R2288S	2288	Missense	distal	-4	no	23.298	22.832	EPSD;PhosphoSitePlus	COSMIC	19.028	Down-regulation
STE_STE20_PAKA_PAK1_ST	P21333	FLNA	Q13153	PAK1	S2292	R2288C	2288	Missense	distal	-4	no	23.298	22.339	EPSD;PhosphoSitePlus	COSMIC	19.028	Down-regulation
STE_STE20_PAKA_PAK1_ST	P21333	FLNA	Q13153	PAK1	S2292	V2298D	2298	Missense	distal	6	no	23.298	23.001	EPSD;PhosphoSitePlus	COSMIC	19.028	Down-regulation
STE_STE20_PAKA_PAK1_ST	P21333	FLNA	Q13153	PAK1	S2292	V2295M	2295	Missense	distal	3	no	23.298	23.731	EPSD;PhosphoSitePlus	COSMIC	19.028	Up-regulation
STE_STE20_PAKA_PAK1_ST	P21333	FLNA	Q13153	PAK1	T2336	V2337F	2337	Missense	proximal	1	no	27.160	27.497	EPSD	COSMIC	19.028	Up-regulation
STE_STE20_PAKA_PAK1_ST	P21333	FLNA	Q13153	PAK1	T2336	V2337I	2337	Missense	proximal	1	no	27.160	27.483	EPSD	COSMIC	19.028	Up-regulation
STE_STE20_PAKA_PAK1_ST	P21333	FLNA	Q13153	PAK1	T2336	S2343N	2343	Missense	distal	7	no	27.160	27.145	EPSD	COSMIC	19.028	Down-regulation
STE_STE20_PAKA_PAK1_ST	P21333	FLNA	Q13153	PAK1	S2338	V2337F	2337	Missense	proximal	-1	no	16.344	19.062	EPSD	COSMIC	19.028	Gain
STE_STE20_PAKA_PAK1_ST	P21333	FLNA	Q13153	PAK1	S2370	D2365N	2365	Missense	distal	-5	no	24.033	24.186	EPSD;PhosphoSitePlus	COSMIC	19.028	Up-regulation
STE_STE20_PAKA_PAK1_ST	P21333	FLNA	Q13153	PAK1	S2370	S2370N	2370	Missense	central	0	yes	24.033	0.000	EPSD;PhosphoSitePlus	COSMIC	19.028	Loss
STE_STE20_PAKA_PAK1_ST	P21333	FLNA	Q13153	PAK1	S2523	V2522I	2522	Missense	proximal	-1	no	17.919	19.464	EPSD	COSMIC	19.028	Gain
STE_STE20_PAKA_PAK1_ST	P21333	FLNA	Q13153	PAK1	S2615	Y2618C	2618	Missense	distal	3	no	20.003	17.378	EPSD	COSMIC	19.028	Loss
STE_STE20_PAKA_PAK1_ST	O43623	SNAI2	Q13153	PAK1	S87	P88L	88	Missense	proximal	1	no	21.018	21.305	EPSD	COSMIC	19.028	Up-regulation
STE_STE20_PAKA_PAK1_ST	O43623	SNAI2	Q13153	PAK1	S100	H99Q	99	Missense	proximal	-1	no	20.384	21.472	EPSD	COSMIC	19.028	Up-regulation
STE_STE20_PAKA_PAK1_ST	O43623	SNAI2	Q13153	PAK1	S100	D98N	98	Missense	proximal	-2	no	20.384	21.124	EPSD	COSMIC;GDSC;CCLE	19.028	Up-regulation
STE_STE20_PAKA_PAK1_ST	O43623	SNAI2	Q13153	PAK1	S100	G101D	101	Missense	proximal	1	no	20.384	20.563	EPSD	COSMIC	19.028	Up-regulation
STE_STE20_PAKA_PAK1_ST	O43623	SNAI2	Q13153	PAK1	S251	N245D	245	Missense	distal	-6	no	20.662	20.500	PhosphoSitePlus	COSMIC	19.028	Down-regulation
STE_STE20_PAKA_PAK1_ST	O43623	SNAI2	Q13153	PAK1	S251	K258N	258	Missense	distal	7	no	20.662	20.618	PhosphoSitePlus	COSMIC;GDSC;CCLE	19.028	Down-regulation
STE_STE20_PAKA_PAK1_ST	O43623	SNAI2	Q13153	PAK1	S251	L255P	255	Missense	distal	4	no	20.662	22.219	PhosphoSitePlus	COSMIC	19.028	Up-regulation
STE_STE20_PAKA_PAK1_ST	O43623	SNAI2	Q13153	PAK1	S251	S251C	251	Missense	central	0	yes	20.662	0.000	PhosphoSitePlus	COSMIC	19.028	Loss
STE_STE20_PAKA_PAK1_ST	O95863	SNAI1	Q13153	PAK1	S11	F5L	5	Missense	distal	-6	no	20.424	20.980	EPSD	COSMIC	19.028	Up-regulation
STE_STE20_PAKA_PAK1_ST	O95863	SNAI1	Q13153	PAK1	S96	P102S	102	Missense	distal	6	no	19.159	18.911	EPSD	COSMIC	19.028	Loss
STE_STE20_PAKA_PAK1_ST	O95863	SNAI1	Q13153	PAK1	S165	E162K	162	Missense	distal	-3	no	6.188	19.980	EPSD	COSMIC	19.028	Gain
STE_STE20_PAKA_PAK1_ST	O95863	SNAI1	Q13153	PAK1	S175	T177M	177	Missense	proximal	2	no	17.992	19.756	EPSD	COSMIC	19.028	Gain
STE_STE20_PAKA_PAK1_ST	O95863	SNAI1	Q13153	PAK1	S246	H252Y	252	Missense	distal	6	no	20.834	21.299	PhosphoSitePlus	COSMIC	19.028	Up-regulation
STE_STE20_PAKA_PAK1_ST	O95863	SNAI1	Q13153	PAK1	S246	S246F	246	Missense	central	0	yes	20.834	0.000	PhosphoSitePlus	COSMIC	19.028	Loss
STE_STE20_PAKA_PAK1_ST	P52565	ARHGDIA	Q13153	PAK1	S174	S179A	179	Missense	distal	5	no	22.183	22.197	PhosphoSitePlus;EPSD	COSMIC	19.028	Up-regulation
STE_STE20_PAKA_PAK1_ST	P52565	ARHGDIA	Q13153	PAK1	S174	R172W	172	Missense	proximal	-2	no	22.183	9.244	PhosphoSitePlus;EPSD	COSMIC	19.028	Loss
STE_STE20_PAKA_PAK1_ST	P52565	ARHGDIA	Q13153	PAK1	S174	M169L	169	Missense	distal	-5	no	22.183	22.080	PhosphoSitePlus;EPSD	COSMIC	19.028	Down-regulation
STE_STE20_PAKA_PAK1_ST	Q15365	PCBP1	Q13153	PAK1	S43	I39T	39	Missense	distal	-4	no	18.976	19.252	EPSD	COSMIC	19.028	Gain
STE_STE20_PAKA_PAK1_ST	Q15365	PCBP1	Q13153	PAK1	T127	G128W	128	Missense	proximal	1	no	19.625	19.512	EPSD;PhosphoSitePlus	COSMIC	19.028	Down-regulation
STE_STE20_PAKA_PAK1_ST	Q15365	PCBP1	Q13153	PAK1	T127	E122G	122	Missense	distal	-5	no	19.625	20.483	EPSD;PhosphoSitePlus	COSMIC	19.028	Up-regulation
STE_STE20_PAKA_PAK1_ST	Q15365	PCBP1	Q13153	PAK1	S231	A236T	236	Missense	distal	5	no	20.073	20.060	EPSD	COSMIC	19.028	Down-regulation
STE_STE20_PAKA_PAK1_ST	P15056	BRAF	Q13153	PAK1	T167	V168L	168	Missense	proximal	1	no	19.628	19.875	EPSD	COSMIC	19.028	Up-regulation
STE_STE20_PAKA_PAK1_ST	P15056	BRAF	Q13153	PAK1	T167	P162S	162	Missense	distal	-5	no	19.628	18.766	EPSD	COSMIC	19.028	Loss
STE_STE20_PAKA_PAK1_ST	P15056	BRAF	Q13153	PAK1	S314	L312P	312	Missense	proximal	-2	no	14.490	19.529	EPSD	COSMIC	19.028	Gain
STE_STE20_PAKA_PAK1_ST	P15056	BRAF	Q13153	PAK1	S323	A322V	322	Missense	proximal	-1	no	20.800	21.430	EPSD	COSMIC	19.028	Up-regulation
STE_STE20_PAKA_PAK1_ST	P15056	BRAF	Q13153	PAK1	S323	G327W	327	Missense	distal	4	no	20.800	21.106	EPSD	COSMIC	19.028	Up-regulation
STE_STE20_PAKA_PAK1_ST	P15056	BRAF	Q13153	PAK1	S323	S323L	323	Missense	central	0	yes	20.800	0.000	EPSD	COSMIC	19.028	Loss
STE_STE20_PAKA_PAK1_ST	P15056	BRAF	Q13153	PAK1	S323	A322T	322	Missense	proximal	-1	no	20.800	23.830	EPSD	COSMIC	19.028	Up-regulation
STE_STE20_PAKA_PAK1_ST	P15056	BRAF	Q13153	PAK1	S323	I326T	326	Missense	distal	3	no	20.800	19.729	EPSD	COSMIC;GDSC;CCLE	19.028	Down-regulation
STE_STE20_PAKA_PAK1_ST	P15056	BRAF	Q13153	PAK1	S323	P321L	321	Missense	proximal	-2	no	20.800	15.761	EPSD	COSMIC	19.028	Loss
STE_STE20_PAKA_PAK1_ST	P15056	BRAF	Q13153	PAK1	S339	S337P	337	Missense	proximal	-2	no	16.832	21.460	EPSD	COSMIC	19.028	Gain
STE_STE20_PAKA_PAK1_ST	P15056	BRAF	Q13153	PAK1	S363	R360Q	360	Missense	distal	-3	no	19.461	10.737	EPSD	COSMIC	19.028	Loss
STE_STE20_PAKA_PAK1_ST	P15056	BRAF	Q13153	PAK1	S363	S365L	365	Missense	proximal	2	no	19.461	20.274	EPSD	COSMIC	19.028	Up-regulation
STE_STE20_PAKA_PAK1_ST	P15056	BRAF	Q13153	PAK1	S363	R362L	362	Missense	proximal	-1	no	19.461	19.328	EPSD	COSMIC	19.028	Down-regulation
STE_STE20_PAKA_PAK1_ST	P15056	BRAF	Q13153	PAK1	S363	Q356K	356	Missense	distal	-7	no	19.461	19.365	EPSD	COSMIC	19.028	Down-regulation
STE_STE20_PAKA_PAK1_ST	P15056	BRAF	Q13153	PAK1	S363	F357S	357	Missense	distal	-6	no	19.461	20.227	EPSD	COSMIC	19.028	Up-regulation
STE_STE20_PAKA_PAK1_ST	P15056	BRAF	Q13153	PAK1	S364	R360Q	360	Missense	distal	-4	no	22.223	21.754	EPSD	COSMIC	19.028	Down-regulation
STE_STE20_PAKA_PAK1_ST	P15056	BRAF	Q13153	PAK1	S364	S365L	365	Missense	proximal	1	no	22.223	22.394	EPSD	COSMIC	19.028	Up-regulation
STE_STE20_PAKA_PAK1_ST	P15056	BRAF	Q13153	PAK1	S364	R362L	362	Missense	proximal	-2	no	22.223	13.659	EPSD	COSMIC	19.028	Loss
STE_STE20_PAKA_PAK1_ST	P15056	BRAF	Q13153	PAK1	S364	F357S	357	Missense	distal	-7	no	22.223	23.221	EPSD	COSMIC	19.028	Up-regulation
STE_STE20_PAKA_PAK1_ST	P15056	BRAF	Q13153	PAK1	S365	R360Q	360	Missense	distal	-5	no	20.673	20.771	EPSD	COSMIC	19.028	Up-regulation
STE_STE20_PAKA_PAK1_ST	P15056	BRAF	Q13153	PAK1	S365	S365L	365	Missense	central	0	yes	20.673	0.000	EPSD	COSMIC	19.028	Loss
STE_STE20_PAKA_PAK1_ST	P15056	BRAF	Q13153	PAK1	S365	R362L	362	Missense	distal	-3	no	20.673	14.182	EPSD	COSMIC	19.028	Loss
STE_STE20_PAKA_PAK1_ST	P15056	BRAF	Q13153	PAK1	S429	P422A	422	Missense	distal	-7	no	21.489	21.571	EPSD	COSMIC	19.028	Up-regulation
STE_STE20_PAKA_PAK1_ST	P15056	BRAF	Q13153	PAK1	S429	S428L	428	Missense	proximal	-1	no	21.489	22.437	EPSD	COSMIC	19.028	Up-regulation
STE_STE20_PAKA_PAK1_ST	P15056	BRAF	Q13153	PAK1	S429	R424L	424	Missense	distal	-5	no	21.489	22.279	EPSD	COSMIC	19.028	Up-regulation
STE_STE20_PAKA_PAK1_ST	P15056	BRAF	Q13153	PAK1	S430	S428L	428	Missense	proximal	-2	no	19.943	19.531	EPSD	COSMIC	19.028	Down-regulation
STE_STE20_PAKA_PAK1_ST	P15056	BRAF	Q13153	PAK1	S430	R424L	424	Missense	distal	-6	no	19.943	17.722	EPSD	COSMIC	19.028	Loss
STE_STE20_PAKA_PAK1_ST	P15056	BRAF	Q13153	PAK1	T440	S447N	447	Missense	distal	7	no	19.506	19.491	EPSD	COSMIC	19.028	Down-regulation
STE_STE20_PAKA_PAK1_ST	P15056	BRAF	Q13153	PAK1	T440	R443I	443	Missense	distal	3	no	19.506	20.885	EPSD	COSMIC	19.028	Up-regulation
STE_STE20_PAKA_PAK1_ST	P15056	BRAF	Q13153	PAK1	T440	R443T	443	Missense	distal	3	no	19.506	19.814	EPSD	COSMIC	19.028	Up-regulation
STE_STE20_PAKA_PAK1_ST	P15056	BRAF	Q13153	PAK1	T440	K439T	439	Missense	proximal	-1	no	19.506	19.438	EPSD	COSMIC	19.028	Down-regulation
STE_STE20_PAKA_PAK1_ST	P15056	BRAF	Q13153	PAK1	T440	G442S	442	Missense	proximal	2	no	19.506	18.358	EPSD	COSMIC	19.028	Loss
STE_STE20_PAKA_PAK1_ST	P15056	BRAF	Q13153	PAK1	T440	T440P	440	Missense	central	0	yes	19.506	0.000	EPSD	COSMIC	19.028	Loss
STE_STE20_PAKA_PAK1_ST	P15056	BRAF	Q13153	PAK1	T440	L441V	441	Missense	proximal	1	no	19.506	19.259	EPSD	COSMIC	19.028	Down-regulation
STE_STE20_PAKA_PAK1_ST	P15056	BRAF	Q13153	PAK1	T440	K439Q	439	Missense	proximal	-1	no	19.506	18.320	EPSD	COSMIC	19.028	Loss
STE_STE20_PAKA_PAK1_ST	P15056	BRAF	Q13153	PAK1	T440	S447C	447	Missense	distal	7	no	19.506	19.651	EPSD	COSMIC	19.028	Up-regulation
STE_STE20_PAKA_PAK1_ST	P15056	BRAF	Q13153	PAK1	T440	G442D	442	Missense	proximal	2	no	19.506	18.694	EPSD	COSMIC	19.028	Loss
STE_STE20_PAKA_PAK1_ST	P15056	BRAF	Q13153	PAK1	T440	T440I	440	Missense	central	0	yes	19.506	0.000	EPSD	COSMIC	19.028	Loss
STE_STE20_PAKA_PAK1_ST	P15056	BRAF	Q13153	PAK1	S446	S447N	447	Missense	proximal	1	no	31.164	31.256	PhosphoSitePlus	COSMIC	19.028	Up-regulation
STE_STE20_PAKA_PAK1_ST	P15056	BRAF	Q13153	PAK1	S446	P453H	453	Missense	distal	7	no	31.164	31.044	PhosphoSitePlus	COSMIC	19.028	Down-regulation
STE_STE20_PAKA_PAK1_ST	P15056	BRAF	Q13153	PAK1	S446	P453T	453	Missense	distal	7	no	31.164	30.816	PhosphoSitePlus	COSMIC	19.028	Down-regulation
STE_STE20_PAKA_PAK1_ST	P15056	BRAF	Q13153	PAK1	S446	R443I	443	Missense	distal	-3	no	31.164	15.697	PhosphoSitePlus	COSMIC	19.028	Loss
STE_STE20_PAKA_PAK1_ST	P15056	BRAF	Q13153	PAK1	S446	W450L	450	Missense	distal	4	no	31.164	30.444	PhosphoSitePlus	COSMIC	19.028	Down-regulation
STE_STE20_PAKA_PAK1_ST	P15056	BRAF	Q13153	PAK1	S446	R443T	443	Missense	distal	-3	no	31.164	24.907	PhosphoSitePlus	COSMIC	19.028	Down-regulation
STE_STE20_PAKA_PAK1_ST	P15056	BRAF	Q13153	PAK1	S446	K439T	439	Missense	distal	-7	no	31.164	31.182	PhosphoSitePlus	COSMIC	19.028	Up-regulation
STE_STE20_PAKA_PAK1_ST	P15056	BRAF	Q13153	PAK1	S446	G442S	442	Missense	distal	-4	no	31.164	31.584	PhosphoSitePlus	COSMIC	19.028	Up-regulation
STE_STE20_PAKA_PAK1_ST	P15056	BRAF	Q13153	PAK1	S446	T440P	440	Missense	distal	-6	no	31.164	30.123	PhosphoSitePlus	COSMIC	19.028	Down-regulation
STE_STE20_PAKA_PAK1_ST	P15056	BRAF	Q13153	PAK1	S446	L441V	441	Missense	distal	-5	no	31.164	30.906	PhosphoSitePlus	COSMIC	19.028	Down-regulation
STE_STE20_PAKA_PAK1_ST	P15056	BRAF	Q13153	PAK1	S446	K439Q	439	Missense	distal	-7	no	31.164	31.260	PhosphoSitePlus	COSMIC	19.028	Up-regulation
STE_STE20_PAKA_PAK1_ST	P15056	BRAF	Q13153	PAK1	S446	S447C	447	Missense	proximal	1	no	31.164	31.123	PhosphoSitePlus	COSMIC	19.028	Down-regulation
STE_STE20_PAKA_PAK1_ST	P15056	BRAF	Q13153	PAK1	S446	D449E	449	Missense	distal	3	no	31.164	29.953	PhosphoSitePlus	COSMIC	19.028	Down-regulation
STE_STE20_PAKA_PAK1_ST	P15056	BRAF	Q13153	PAK1	S446	G442D	442	Missense	distal	-4	no	31.164	31.644	PhosphoSitePlus	COSMIC	19.028	Up-regulation
STE_STE20_PAKA_PAK1_ST	P15056	BRAF	Q13153	PAK1	S446	T440I	440	Missense	distal	-6	no	31.164	29.116	PhosphoSitePlus	COSMIC	19.028	Down-regulation
STE_STE20_PAKA_PAK1_ST	P15056	BRAF	Q13153	PAK1	S446	W450R	450	Missense	distal	4	no	31.164	29.047	PhosphoSitePlus	COSMIC	19.028	Down-regulation
STE_STE20_PAKA_PAK1_ST	P15056	BRAF	Q13153	PAK1	S446	D449Y	449	Missense	distal	3	no	31.164	33.500	PhosphoSitePlus	COSMIC	19.028	Up-regulation
STE_STE20_PAKA_PAK1_ST	P15056	BRAF	Q13153	PAK1	S447	S447N	447	Missense	central	0	yes	23.244	0.000	EPSD	COSMIC	19.028	Loss
STE_STE20_PAKA_PAK1_ST	P15056	BRAF	Q13153	PAK1	S447	P453H	453	Missense	distal	6	no	23.244	23.175	EPSD	COSMIC	19.028	Down-regulation
STE_STE20_PAKA_PAK1_ST	P15056	BRAF	Q13153	PAK1	S447	P453T	453	Missense	distal	6	no	23.244	22.721	EPSD	COSMIC	19.028	Down-regulation
STE_STE20_PAKA_PAK1_ST	P15056	BRAF	Q13153	PAK1	S447	R443I	443	Missense	distal	-4	no	23.244	23.014	EPSD	COSMIC	19.028	Down-regulation
STE_STE20_PAKA_PAK1_ST	P15056	BRAF	Q13153	PAK1	S447	W450L	450	Missense	distal	3	no	23.244	22.476	EPSD	COSMIC	19.028	Down-regulation
STE_STE20_PAKA_PAK1_ST	P15056	BRAF	Q13153	PAK1	S447	R443T	443	Missense	distal	-4	no	23.244	23.290	EPSD	COSMIC	19.028	Up-regulation
STE_STE20_PAKA_PAK1_ST	P15056	BRAF	Q13153	PAK1	S447	G442S	442	Missense	distal	-5	no	23.244	22.329	EPSD	COSMIC	19.028	Down-regulation
STE_STE20_PAKA_PAK1_ST	P15056	BRAF	Q13153	PAK1	S447	T440P	440	Missense	distal	-7	no	23.244	23.018	EPSD	COSMIC	19.028	Down-regulation
STE_STE20_PAKA_PAK1_ST	P15056	BRAF	Q13153	PAK1	S447	D454N	454	Missense	distal	7	no	23.244	23.239	EPSD	COSMIC	19.028	Down-regulation
STE_STE20_PAKA_PAK1_ST	P15056	BRAF	Q13153	PAK1	S447	L441V	441	Missense	distal	-6	no	23.244	23.725	EPSD	COSMIC	19.028	Up-regulation
STE_STE20_PAKA_PAK1_ST	P15056	BRAF	Q13153	PAK1	S447	S447C	447	Missense	central	0	yes	23.244	0.000	EPSD	COSMIC	19.028	Loss
STE_STE20_PAKA_PAK1_ST	P15056	BRAF	Q13153	PAK1	S447	D449E	449	Missense	proximal	2	no	23.244	22.934	EPSD	COSMIC	19.028	Down-regulation
STE_STE20_PAKA_PAK1_ST	P15056	BRAF	Q13153	PAK1	S447	G442D	442	Missense	distal	-5	no	23.244	22.812	EPSD	COSMIC	19.028	Down-regulation
STE_STE20_PAKA_PAK1_ST	P15056	BRAF	Q13153	PAK1	S447	T440I	440	Missense	distal	-7	no	23.244	22.447	EPSD	COSMIC	19.028	Down-regulation
STE_STE20_PAKA_PAK1_ST	P15056	BRAF	Q13153	PAK1	S447	W450R	450	Missense	distal	3	no	23.244	20.840	EPSD	COSMIC	19.028	Down-regulation
STE_STE20_PAKA_PAK1_ST	P15056	BRAF	Q13153	PAK1	S447	D449Y	449	Missense	proximal	2	no	23.244	25.159	EPSD	COSMIC	19.028	Up-regulation
STE_STE20_PAKA_PAK1_ST	P15056	BRAF	Q13153	PAK1	S465	G469X	469	Missense	distal	4	no	21.053	20.892	EPSD	COSMIC	19.028	Down-regulation
STE_STE20_PAKA_PAK1_ST	P15056	BRAF	Q13153	PAK1	S465	G469S	469	Missense	distal	4	no	21.053	19.845	EPSD	COSMIC	19.028	Down-regulation
STE_STE20_PAKA_PAK1_ST	P15056	BRAF	Q13153	PAK1	S465	Y472S	472	Missense	distal	7	no	21.053	20.809	EPSD	COSMIC	19.028	Down-regulation
STE_STE20_PAKA_PAK1_ST	P15056	BRAF	Q13153	PAK1	S465	Y472C	472	Missense	distal	7	no	21.053	20.954	EPSD	COSMIC	19.028	Down-regulation
STE_STE20_PAKA_PAK1_ST	P15056	BRAF	Q13153	PAK1	S465	S467F	467	Missense	proximal	2	no	21.053	21.136	EPSD	COSMIC	19.028	Up-regulation
STE_STE20_PAKA_PAK1_ST	P15056	BRAF	Q13153	PAK1	S465	V459L	459	Missense	distal	-6	no	21.053	20.571	EPSD	COSMIC	19.028	Down-regulation
STE_STE20_PAKA_PAK1_ST	P15056	BRAF	Q13153	PAK1	S465	G464R	464	Missense	proximal	-1	no	21.053	25.121	EPSD	COSMIC	19.028	Up-regulation
STE_STE20_PAKA_PAK1_ST	P15056	BRAF	Q13153	PAK1	S465	G469L	469	Missense	distal	4	no	21.053	20.638	EPSD	COSMIC	19.028	Down-regulation
STE_STE20_PAKA_PAK1_ST	P15056	BRAF	Q13153	PAK1	S465	F468S	468	Missense	distal	3	no	21.053	20.472	EPSD	COSMIC	19.028	Down-regulation
STE_STE20_PAKA_PAK1_ST	P15056	BRAF	Q13153	PAK1	S465	S465F	465	Missense	central	0	yes	21.053	0.000	EPSD	COSMIC	19.028	Loss
STE_STE20_PAKA_PAK1_ST	P15056	BRAF	Q13153	PAK1	S465	V471A	471	Missense	distal	6	no	21.053	20.731	EPSD	COSMIC	19.028	Down-regulation
STE_STE20_PAKA_PAK1_ST	P15056	BRAF	Q13153	PAK1	S465	R462I	462	Missense	distal	-3	no	21.053	5.586	EPSD	COSMIC	19.028	Loss
STE_STE20_PAKA_PAK1_ST	P15056	BRAF	Q13153	PAK1	S465	T470I	470	Missense	distal	5	no	21.053	21.058	EPSD	COSMIC	19.028	Up-regulation
STE_STE20_PAKA_PAK1_ST	P15056	BRAF	Q13153	PAK1	S465	I463N	463	Missense	proximal	-2	no	21.053	21.742	EPSD	COSMIC	19.028	Up-regulation
STE_STE20_PAKA_PAK1_ST	P15056	BRAF	Q13153	PAK1	S465	G460R	460	Missense	distal	-5	no	21.053	20.108	EPSD	COSMIC	19.028	Down-regulation
STE_STE20_PAKA_PAK1_ST	P15056	BRAF	Q13153	PAK1	S465	F468L	468	Missense	distal	3	no	21.053	22.266	EPSD	COSMIC	19.028	Up-regulation
STE_STE20_PAKA_PAK1_ST	P15056	BRAF	Q13153	PAK1	S465	I463S	463	Missense	proximal	-2	no	21.053	19.184	EPSD	COSMIC	19.028	Down-regulation
STE_STE20_PAKA_PAK1_ST	P15056	BRAF	Q13153	PAK1	S602	T599R	599	Missense	distal	-3	no	16.111	22.369	EPSD	COSMIC	19.028	Gain
STE_STE20_PAKA_PAK1_ST	Q96T58	SPEN	Q13153	PAK1	S43	A48T	48	Missense	distal	5	no	28.417	28.404	EPSD	COSMIC	19.028	Down-regulation
STE_STE20_PAKA_PAK1_ST	Q96T58	SPEN	Q13153	PAK1	S43	G45V	45	Missense	proximal	2	no	28.417	28.243	EPSD	COSMIC	19.028	Down-regulation
STE_STE20_PAKA_PAK1_ST	Q96T58	SPEN	Q13153	PAK1	S43	R41S	41	Missense	proximal	-2	no	28.417	20.265	EPSD	COSMIC	19.028	Down-regulation
STE_STE20_PAKA_PAK1_ST	Q96T58	SPEN	Q13153	PAK1	S43	P39L	39	Missense	distal	-4	no	28.417	28.623	EPSD	COSMIC	19.028	Up-regulation
STE_STE20_PAKA_PAK1_ST	Q96T58	SPEN	Q13153	PAK1	S147	R142H	142	Missense	distal	-5	no	22.087	22.534	EPSD	COSMIC	19.028	Up-regulation
STE_STE20_PAKA_PAK1_ST	Q96T58	SPEN	Q13153	PAK1	T177	L182I	182	Missense	distal	5	no	20.661	20.654	EPSD	COSMIC	19.028	Down-regulation
STE_STE20_PAKA_PAK1_ST	Q96T58	SPEN	Q13153	PAK1	T177	R176Q	176	Missense	proximal	-1	no	20.661	18.942	EPSD	COSMIC	19.028	Loss
STE_STE20_PAKA_PAK1_ST	Q96T58	SPEN	Q13153	PAK1	S244	S248P	248	Missense	distal	4	no	17.594	19.944	EPSD	COSMIC	19.028	Gain
STE_STE20_PAKA_PAK1_ST	Q96T58	SPEN	Q13153	PAK1	T266	P265T	265	Missense	proximal	-1	no	15.385	19.108	EPSD	COSMIC	19.028	Gain
STE_STE20_PAKA_PAK1_ST	Q96T58	SPEN	Q13153	PAK1	S270	G271S	271	Missense	proximal	1	no	22.190	22.268	EPSD	COSMIC	19.028	Up-regulation
STE_STE20_PAKA_PAK1_ST	Q96T58	SPEN	Q13153	PAK1	S270	P265T	265	Missense	distal	-5	no	22.190	21.756	EPSD	COSMIC	19.028	Down-regulation
STE_STE20_PAKA_PAK1_ST	Q96T58	SPEN	Q13153	PAK1	S270	S268F	268	Missense	proximal	-2	no	22.190	24.724	EPSD	COSMIC;GDSC;CCLE	19.028	Up-regulation
STE_STE20_PAKA_PAK1_ST	Q96T58	SPEN	Q13153	PAK1	S270	P269S	269	Missense	proximal	-1	no	22.190	25.433	EPSD	COSMIC	19.028	Up-regulation
STE_STE20_PAKA_PAK1_ST	Q96T58	SPEN	Q13153	PAK1	S278	G271S	271	Missense	distal	-7	no	20.454	21.391	EPSD	COSMIC	19.028	Up-regulation
STE_STE20_PAKA_PAK1_ST	Q96T58	SPEN	Q13153	PAK1	S305	S302R	302	Missense	distal	-3	no	11.560	20.232	EPSD	COSMIC	19.028	Gain
STE_STE20_PAKA_PAK1_ST	Q96T58	SPEN	Q13153	PAK1	S334	V339I	339	Missense	distal	5	no	27.419	27.410	EPSD	COSMIC	19.028	Down-regulation
STE_STE20_PAKA_PAK1_ST	Q96T58	SPEN	Q13153	PAK1	S334	F335L	335	Missense	proximal	1	no	27.419	27.329	EPSD	COSMIC	19.028	Down-regulation
STE_STE20_PAKA_PAK1_ST	Q96T58	SPEN	Q13153	PAK1	S334	F335I	335	Missense	proximal	1	no	27.419	27.405	EPSD	COSMIC	19.028	Down-regulation
STE_STE20_PAKA_PAK1_ST	Q96T58	SPEN	Q13153	PAK1	S623	D625N	625	Missense	proximal	2	no	30.999	31.010	EPSD	COSMIC	19.028	Up-regulation
STE_STE20_PAKA_PAK1_ST	Q96T58	SPEN	Q13153	PAK1	S623	Y624C	624	Missense	proximal	1	no	30.999	31.046	EPSD	COSMIC	19.028	Up-regulation
STE_STE20_PAKA_PAK1_ST	Q96T58	SPEN	Q13153	PAK1	S623	E619K	619	Missense	distal	-4	no	30.999	31.077	EPSD	COSMIC	19.028	Up-regulation
STE_STE20_PAKA_PAK1_ST	Q96T58	SPEN	Q13153	PAK1	T638	T641A	641	Missense	distal	3	no	18.221	19.467	EPSD	COSMIC	19.028	Gain
STE_STE20_PAKA_PAK1_ST	Q96T58	SPEN	Q13153	PAK1	T638	S635R	635	Missense	distal	-3	no	18.221	26.892	EPSD	COSMIC	19.028	Gain
STE_STE20_PAKA_PAK1_ST	Q96T58	SPEN	Q13153	PAK1	S696	R700K	700	Missense	distal	4	no	21.448	22.451	EPSD	COSMIC	19.028	Up-regulation
STE_STE20_PAKA_PAK1_ST	Q96T58	SPEN	Q13153	PAK1	S696	R693K	693	Missense	distal	-3	no	21.448	20.261	EPSD	COSMIC	19.028	Down-regulation
STE_STE20_PAKA_PAK1_ST	Q96T58	SPEN	Q13153	PAK1	S696	Y695C	695	Missense	proximal	-1	no	21.448	19.189	EPSD	COSMIC	19.028	Down-regulation
STE_STE20_PAKA_PAK1_ST	Q96T58	SPEN	Q13153	PAK1	S696	R693M	693	Missense	distal	-3	no	21.448	13.879	EPSD	COSMIC	19.028	Loss
STE_STE20_PAKA_PAK1_ST	Q96T58	SPEN	Q13153	PAK1	S727	S727N	727	Missense	central	0	yes	19.497	0.000	EPSD	COSMIC	19.028	Loss
STE_STE20_PAKA_PAK1_ST	Q96T58	SPEN	Q13153	PAK1	S727	S725R	725	Missense	proximal	-2	no	19.497	27.649	EPSD	COSMIC	19.028	Up-regulation
STE_STE20_PAKA_PAK1_ST	Q96T58	SPEN	Q13153	PAK1	S727	P728L	728	Missense	proximal	1	no	19.497	19.784	EPSD	COSMIC	19.028	Up-regulation
STE_STE20_PAKA_PAK1_ST	Q96T58	SPEN	Q13153	PAK1	S736	S742F	742	Missense	distal	6	no	25.750	26.126	EPSD	COSMIC	19.028	Up-regulation
STE_STE20_PAKA_PAK1_ST	Q96T58	SPEN	Q13153	PAK1	S736	G738E	738	Missense	proximal	2	no	25.750	24.629	EPSD	COSMIC	19.028	Down-regulation
STE_STE20_PAKA_PAK1_ST	Q96T58	SPEN	Q13153	PAK1	S736	P737S	737	Missense	proximal	1	no	25.750	25.867	EPSD	COSMIC	19.028	Up-regulation
STE_STE20_PAKA_PAK1_ST	Q96T58	SPEN	Q13153	PAK1	S736	Q743E	743	Missense	distal	7	no	25.750	25.822	EPSD	COSMIC	19.028	Up-regulation
STE_STE20_PAKA_PAK1_ST	Q96T58	SPEN	Q13153	PAK1	S830	S832G	832	Missense	proximal	2	no	18.433	19.581	EPSD	COSMIC	19.028	Gain
STE_STE20_PAKA_PAK1_ST	Q96T58	SPEN	Q13153	PAK1	S847	R844Q	844	Missense	distal	-3	no	22.026	13.302	EPSD	COSMIC	19.028	Loss
STE_STE20_PAKA_PAK1_ST	Q96T58	SPEN	Q13153	PAK1	S847	P851L	851	Missense	distal	4	no	22.026	20.469	EPSD	COSMIC	19.028	Down-regulation
STE_STE20_PAKA_PAK1_ST	Q96T58	SPEN	Q13153	PAK1	S847	S853N	853	Missense	distal	6	no	22.026	22.211	EPSD	COSMIC	19.028	Up-regulation
STE_STE20_PAKA_PAK1_ST	Q96T58	SPEN	Q13153	PAK1	S946	S946L	946	Missense	central	0	yes	20.456	0.000	EPSD	COSMIC	19.028	Loss
STE_STE20_PAKA_PAK1_ST	Q96T58	SPEN	Q13153	PAK1	S946	K943R	943	Missense	distal	-3	no	20.456	21.643	EPSD	COSMIC	19.028	Up-regulation
STE_STE20_PAKA_PAK1_ST	Q96T58	SPEN	Q13153	PAK1	S946	V951M	951	Missense	distal	5	no	20.456	20.472	EPSD	COSMIC	19.028	Up-regulation
STE_STE20_PAKA_PAK1_ST	Q96T58	SPEN	Q13153	PAK1	S1006	D1011G	1011	Missense	distal	5	no	20.962	20.985	EPSD	COSMIC	19.028	Up-regulation
STE_STE20_PAKA_PAK1_ST	Q96T58	SPEN	Q13153	PAK1	S1006	R1013C	1013	Missense	distal	7	no	20.962	21.200	EPSD	COSMIC	19.028	Up-regulation
STE_STE20_PAKA_PAK1_ST	Q96T58	SPEN	Q13153	PAK1	S1006	S1006C	1006	Missense	central	0	yes	20.962	0.000	EPSD	COSMIC	19.028	Loss
STE_STE20_PAKA_PAK1_ST	Q96T58	SPEN	Q13153	PAK1	S1006	P1007L	1007	Missense	proximal	1	no	20.962	21.249	EPSD	COSMIC	19.028	Up-regulation
STE_STE20_PAKA_PAK1_ST	Q96T58	SPEN	Q13153	PAK1	S1006	P1000L	1000	Missense	distal	-6	no	20.962	20.809	EPSD	COSMIC	19.028	Down-regulation
STE_STE20_PAKA_PAK1_ST	Q96T58	SPEN	Q13153	PAK1	S1082	S1082L	1082	Missense	central	0	yes	20.210	0.000	EPSD	COSMIC;GDSC;CCLE	19.028	Loss
STE_STE20_PAKA_PAK1_ST	Q96T58	SPEN	Q13153	PAK1	S1222	P1224L	1224	Missense	proximal	2	no	18.988	19.156	EPSD	COSMIC	19.028	Gain
STE_STE20_PAKA_PAK1_ST	Q96T58	SPEN	Q13153	PAK1	S1222	P1223H	1223	Missense	proximal	1	no	18.988	19.245	EPSD	COSMIC	19.028	Gain
STE_STE20_PAKA_PAK1_ST	Q96T58	SPEN	Q13153	PAK1	S1222	S1225N	1225	Missense	distal	3	no	18.988	20.708	EPSD	COSMIC	19.028	Gain
STE_STE20_PAKA_PAK1_ST	Q96T58	SPEN	Q13153	PAK1	S1222	P1215S	1215	Missense	distal	-7	no	18.988	19.245	EPSD	COSMIC	19.028	Gain
STE_STE20_PAKA_PAK1_ST	Q96T58	SPEN	Q13153	PAK1	S1222	D1220N	1220	Missense	proximal	-2	no	18.988	19.728	EPSD	COSMIC	19.028	Gain
STE_STE20_PAKA_PAK1_ST	Q96T58	SPEN	Q13153	PAK1	S1225	P1224L	1224	Missense	proximal	-1	no	15.948	20.140	EPSD	COSMIC	19.028	Gain
STE_STE20_PAKA_PAK1_ST	Q96T58	SPEN	Q13153	PAK1	S1268	D1274Y	1274	Missense	distal	6	no	18.755	19.358	EPSD	COSMIC	19.028	Gain
STE_STE20_PAKA_PAK1_ST	Q96T58	SPEN	Q13153	PAK1	S1268	E1271A	1271	Missense	distal	3	no	18.755	20.236	EPSD	COSMIC;GDSC	19.028	Gain
STE_STE20_PAKA_PAK1_ST	Q96T58	SPEN	Q13153	PAK1	S1268	E1271G	1271	Missense	distal	3	no	18.755	21.267	EPSD	COSMIC	19.028	Gain
STE_STE20_PAKA_PAK1_ST	Q96T58	SPEN	Q13153	PAK1	S1268	H1270Y	1270	Missense	proximal	2	no	18.755	21.073	EPSD	COSMIC	19.028	Gain
STE_STE20_PAKA_PAK1_ST	Q96T58	SPEN	Q13153	PAK1	S1369	G1376D	1376	Missense	distal	7	no	22.353	22.268	EPSD	COSMIC	19.028	Down-regulation
STE_STE20_PAKA_PAK1_ST	Q96T58	SPEN	Q13153	PAK1	S1396	E1400K	1400	Missense	distal	4	no	23.744	23.892	EPSD	COSMIC	19.028	Up-regulation
STE_STE20_PAKA_PAK1_ST	Q96T58	SPEN	Q13153	PAK1	S1396	E1400A	1400	Missense	distal	4	no	23.744	24.469	EPSD	COSMIC	19.028	Up-regulation
STE_STE20_PAKA_PAK1_ST	Q96T58	SPEN	Q13153	PAK1	S1402	E1400K	1400	Missense	proximal	-2	no	20.231	22.714	EPSD	COSMIC	19.028	Up-regulation
STE_STE20_PAKA_PAK1_ST	Q96T58	SPEN	Q13153	PAK1	S1402	E1400A	1400	Missense	proximal	-2	no	20.231	18.932	EPSD	COSMIC	19.028	Loss
STE_STE20_PAKA_PAK1_ST	Q96T58	SPEN	Q13153	PAK1	S1402	S1405C	1405	Missense	distal	3	no	20.231	21.386	EPSD	COSMIC	19.028	Up-regulation
STE_STE20_PAKA_PAK1_ST	Q96T58	SPEN	Q13153	PAK1	S1405	E1400A	1400	Missense	distal	-5	no	18.952	19.522	EPSD	COSMIC	19.028	Gain
STE_STE20_PAKA_PAK1_ST	Q96T58	SPEN	Q13153	PAK1	S1424	L1426V	1426	Missense	proximal	2	no	19.984	20.145	EPSD	COSMIC	19.028	Up-regulation
STE_STE20_PAKA_PAK1_ST	Q96T58	SPEN	Q13153	PAK1	S1433	L1426V	1426	Missense	distal	-7	no	21.348	20.446	EPSD	COSMIC	19.028	Down-regulation
STE_STE20_PAKA_PAK1_ST	Q96T58	SPEN	Q13153	PAK1	S1433	S1433Y	1433	Missense	central	0	yes	21.348	0.000	EPSD	COSMIC;GDSC;CCLE	19.028	Loss
STE_STE20_PAKA_PAK1_ST	Q96T58	SPEN	Q13153	PAK1	T1441	T1444S	1444	Missense	distal	3	no	19.825	19.358	EPSD	COSMIC	19.028	Down-regulation
STE_STE20_PAKA_PAK1_ST	Q96T58	SPEN	Q13153	PAK1	S1453	S1455P	1455	Missense	proximal	2	no	19.527	20.172	EPSD	COSMIC	19.028	Up-regulation
STE_STE20_PAKA_PAK1_ST	Q96T58	SPEN	Q13153	PAK1	S1453	S1455F	1455	Missense	proximal	2	no	19.527	19.611	EPSD	COSMIC	19.028	Up-regulation
STE_STE20_PAKA_PAK1_ST	Q96T58	SPEN	Q13153	PAK1	S1453	S1455A	1455	Missense	proximal	2	no	19.527	20.431	EPSD	COSMIC	19.028	Up-regulation
STE_STE20_PAKA_PAK1_ST	Q96T58	SPEN	Q13153	PAK1	S1453	R1458L	1458	Missense	distal	5	no	19.527	19.541	EPSD	COSMIC	19.028	Up-regulation
STE_STE20_PAKA_PAK1_ST	Q96T58	SPEN	Q13153	PAK1	S1455	S1455P	1455	Missense	central	0	yes	19.989	0.000	EPSD	COSMIC	19.028	Loss
STE_STE20_PAKA_PAK1_ST	Q96T58	SPEN	Q13153	PAK1	S1455	S1455F	1455	Missense	central	0	yes	19.989	0.000	EPSD	COSMIC	19.028	Loss
STE_STE20_PAKA_PAK1_ST	Q96T58	SPEN	Q13153	PAK1	S1455	S1455A	1455	Missense	central	0	yes	19.989	0.000	EPSD	COSMIC	19.028	Loss
STE_STE20_PAKA_PAK1_ST	Q96T58	SPEN	Q13153	PAK1	S1455	R1458L	1458	Missense	distal	3	no	19.989	21.624	EPSD	COSMIC	19.028	Up-regulation
STE_STE20_PAKA_PAK1_ST	Q96T58	SPEN	Q13153	PAK1	S1455	N1461H	1461	Missense	distal	6	no	19.989	19.984	EPSD	COSMIC	19.028	Down-regulation
STE_STE20_PAKA_PAK1_ST	Q96T58	SPEN	Q13153	PAK1	S1485	D1484V	1484	Missense	proximal	-1	no	23.714	22.424	EPSD	COSMIC	19.028	Down-regulation
STE_STE20_PAKA_PAK1_ST	Q96T58	SPEN	Q13153	PAK1	S1485	E1481K	1481	Missense	distal	-4	no	23.714	23.793	EPSD	COSMIC	19.028	Up-regulation
STE_STE20_PAKA_PAK1_ST	Q96T58	SPEN	Q13153	PAK1	S1485	V1483I	1483	Missense	proximal	-2	no	23.714	22.989	EPSD	COSMIC	19.028	Down-regulation
STE_STE20_PAKA_PAK1_ST	Q96T58	SPEN	Q13153	PAK1	S1504	G1506W	1506	Missense	proximal	2	no	24.271	24.575	EPSD	COSMIC	19.028	Up-regulation
STE_STE20_PAKA_PAK1_ST	Q96T58	SPEN	Q13153	PAK1	S1557	D1554N	1554	Missense	distal	-3	no	21.149	19.074	EPSD	COSMIC	19.028	Down-regulation
STE_STE20_PAKA_PAK1_ST	Q96T58	SPEN	Q13153	PAK1	S1557	R1559S	1559	Missense	proximal	2	no	21.149	21.535	EPSD	COSMIC	19.028	Up-regulation
STE_STE20_PAKA_PAK1_ST	Q96T58	SPEN	Q13153	PAK1	S1557	D1552N	1552	Missense	distal	-5	no	21.149	21.302	EPSD	COSMIC	19.028	Up-regulation
STE_STE20_PAKA_PAK1_ST	Q96T58	SPEN	Q13153	PAK1	S1557	E1551D	1551	Missense	distal	-6	no	21.149	20.252	EPSD	COSMIC	19.028	Down-regulation
STE_STE20_PAKA_PAK1_ST	Q96T58	SPEN	Q13153	PAK1	S1575	T1573I	1573	Missense	proximal	-2	no	21.755	20.333	EPSD	COSMIC	19.028	Down-regulation
STE_STE20_PAKA_PAK1_ST	Q96T58	SPEN	Q13153	PAK1	S1622	E1621K	1621	Missense	proximal	-1	no	18.010	20.491	EPSD	COSMIC	19.028	Gain
STE_STE20_PAKA_PAK1_ST	Q96T58	SPEN	Q13153	PAK1	S1797	S1802P	1802	Missense	distal	5	no	19.532	19.560	EPSD	COSMIC	19.028	Up-regulation
STE_STE20_PAKA_PAK1_ST	Q96T58	SPEN	Q13153	PAK1	S1802	S1802P	1802	Missense	central	0	yes	19.738	0.000	EPSD	COSMIC	19.028	Loss
STE_STE20_PAKA_PAK1_ST	Q96T58	SPEN	Q13153	PAK1	S1802	P1809L	1809	Missense	distal	7	no	19.738	19.719	EPSD	COSMIC	19.028	Down-regulation
STE_STE20_PAKA_PAK1_ST	Q96T58	SPEN	Q13153	PAK1	S1855	R1859W	1859	Missense	distal	4	no	18.792	20.909	EPSD	COSMIC;GDSC;CCLE	19.028	Gain
STE_STE20_PAKA_PAK1_ST	Q96T58	SPEN	Q13153	PAK1	S1855	N1856T	1856	Missense	proximal	1	no	18.792	19.109	EPSD	COSMIC	19.028	Gain
STE_STE20_PAKA_PAK1_ST	Q96T58	SPEN	Q13153	PAK1	S1897	R1898Q	1898	Missense	proximal	1	no	19.043	18.708	EPSD	COSMIC	19.028	Loss
STE_STE20_PAKA_PAK1_ST	Q96T58	SPEN	Q13153	PAK1	S1897	P1892S	1892	Missense	distal	-5	no	19.043	18.182	EPSD	COSMIC	19.028	Loss
STE_STE20_PAKA_PAK1_ST	Q96T58	SPEN	Q13153	PAK1	S1897	R1902Q	1902	Missense	distal	5	no	19.043	19.041	EPSD	COSMIC	19.028	Down-regulation
STE_STE20_PAKA_PAK1_ST	Q96T58	SPEN	Q13153	PAK1	T1974	A1972E	1972	Missense	proximal	-2	no	18.454	19.753	EPSD	COSMIC	19.028	Gain
STE_STE20_PAKA_PAK1_ST	Q96T58	SPEN	Q13153	PAK1	S1986	S1983L	1983	Missense	distal	-3	no	19.175	21.356	EPSD	COSMIC;GDSC;CCLE	19.028	Up-regulation
STE_STE20_PAKA_PAK1_ST	Q96T58	SPEN	Q13153	PAK1	S1986	E1979Q	1979	Missense	distal	-7	no	19.175	18.542	EPSD	COSMIC	19.028	Loss
STE_STE20_PAKA_PAK1_ST	Q96T58	SPEN	Q13153	PAK1	S1986	G1980E	1980	Missense	distal	-6	no	19.175	20.570	EPSD	COSMIC	19.028	Up-regulation
STE_STE20_PAKA_PAK1_ST	Q96T58	SPEN	Q13153	PAK1	S1986	S1986F	1986	Missense	central	0	yes	19.175	0.000	EPSD	COSMIC	19.028	Loss
STE_STE20_PAKA_PAK1_ST	Q96T58	SPEN	Q13153	PAK1	S2392	S2392F	2392	Missense	central	0	yes	28.081	0.000	EPSD	COSMIC	19.028	Loss
STE_STE20_PAKA_PAK1_ST	Q96T58	SPEN	Q13153	PAK1	S2392	Q2396R	2396	Missense	distal	4	no	28.081	27.792	EPSD	COSMIC;CCLE	19.028	Down-regulation
STE_STE20_PAKA_PAK1_ST	Q96T58	SPEN	Q13153	PAK1	S2392	Q2396E	2396	Missense	distal	4	no	28.081	28.646	EPSD	COSMIC	19.028	Up-regulation
STE_STE20_PAKA_PAK1_ST	Q96T58	SPEN	Q13153	PAK1	S2397	S2392F	2392	Missense	distal	-5	no	19.084	19.514	EPSD	COSMIC	19.028	Up-regulation
STE_STE20_PAKA_PAK1_ST	Q96T58	SPEN	Q13153	PAK1	S2397	L2402P	2402	Missense	distal	5	no	19.084	19.099	EPSD	COSMIC	19.028	Up-regulation
STE_STE20_PAKA_PAK1_ST	Q96T58	SPEN	Q13153	PAK1	S2397	Q2396R	2396	Missense	proximal	-1	no	19.084	20.803	EPSD	COSMIC;CCLE	19.028	Up-regulation
STE_STE20_PAKA_PAK1_ST	Q96T58	SPEN	Q13153	PAK1	S2397	Q2396E	2396	Missense	proximal	-1	no	19.084	17.788	EPSD	COSMIC	19.028	Loss
STE_STE20_PAKA_PAK1_ST	Q96T58	SPEN	Q13153	PAK1	S2407	L2402P	2402	Missense	distal	-5	no	19.744	19.845	EPSD	COSMIC	19.028	Up-regulation
STE_STE20_PAKA_PAK1_ST	Q96T58	SPEN	Q13153	PAK1	S2407	S2411P	2411	Missense	distal	4	no	19.744	22.094	EPSD	COSMIC	19.028	Up-regulation
STE_STE20_PAKA_PAK1_ST	Q96T58	SPEN	Q13153	PAK1	S2407	E2409D	2409	Missense	proximal	2	no	19.744	20.053	EPSD	COSMIC	19.028	Up-regulation
STE_STE20_PAKA_PAK1_ST	Q96T58	SPEN	Q13153	PAK1	S2407	N2410S	2410	Missense	distal	3	no	19.744	18.023	EPSD	COSMIC	19.028	Loss
STE_STE20_PAKA_PAK1_ST	Q96T58	SPEN	Q13153	PAK1	S2452	S2452F	2452	Missense	central	0	yes	23.633	0.000	EPSD	COSMIC;GDSC;CCLE	19.028	Loss
STE_STE20_PAKA_PAK1_ST	Q96T58	SPEN	Q13153	PAK1	S2481	A2485T	2485	Missense	distal	4	no	20.164	18.821	EPSD	COSMIC	19.028	Loss
STE_STE20_PAKA_PAK1_ST	Q96T58	SPEN	Q13153	PAK1	S2481	G2488W	2488	Missense	distal	7	no	20.164	20.179	EPSD	COSMIC	19.028	Up-regulation
STE_STE20_PAKA_PAK1_ST	Q96T58	SPEN	Q13153	PAK1	S2481	G2488E	2488	Missense	distal	7	no	20.164	20.064	EPSD	COSMIC	19.028	Down-regulation
STE_STE20_PAKA_PAK1_ST	Q96T58	SPEN	Q13153	PAK1	S2512	R2509Q	2509	Missense	distal	-3	no	21.026	12.301	EPSD	COSMIC	19.028	Loss
STE_STE20_PAKA_PAK1_ST	Q96T58	SPEN	Q13153	PAK1	S2512	P2508S	2508	Missense	distal	-4	no	21.026	21.078	EPSD	COSMIC	19.028	Up-regulation
STE_STE20_PAKA_PAK1_ST	Q96T58	SPEN	Q13153	PAK1	S2512	A2510V	2510	Missense	proximal	-2	no	21.026	23.286	EPSD	COSMIC;GDSC	19.028	Up-regulation
STE_STE20_PAKA_PAK1_ST	Q96T58	SPEN	Q13153	PAK1	T2685	V2690M	2690	Missense	distal	5	no	19.856	19.871	EPSD	COSMIC	19.028	Up-regulation
STE_STE20_PAKA_PAK1_ST	Q96T58	SPEN	Q13153	PAK1	T2685	A2687D	2687	Missense	proximal	2	no	19.856	19.288	EPSD	COSMIC	19.028	Down-regulation
STE_STE20_PAKA_PAK1_ST	Q96T58	SPEN	Q13153	PAK1	T2685	V2690L	2690	Missense	distal	5	no	19.856	19.854	EPSD	COSMIC	19.028	Down-regulation
STE_STE20_PAKA_PAK1_ST	Q96T58	SPEN	Q13153	PAK1	S2860	A2863S	2863	Missense	distal	3	no	19.348	17.635	EPSD	COSMIC	19.028	Loss
STE_STE20_PAKA_PAK1_ST	Q96T58	SPEN	Q13153	PAK1	S2860	S2860F	2860	Missense	central	0	yes	19.348	0.000	EPSD	COSMIC	19.028	Loss
STE_STE20_PAKA_PAK1_ST	Q96T58	SPEN	Q13153	PAK1	S3014	A3019T	3019	Missense	distal	5	no	22.994	22.980	EPSD	COSMIC	19.028	Down-regulation
STE_STE20_PAKA_PAK1_ST	Q96T58	SPEN	Q13153	PAK1	S3014	H3015Y	3015	Missense	proximal	1	no	22.994	22.764	EPSD	COSMIC	19.028	Down-regulation
STE_STE20_PAKA_PAK1_ST	Q96T58	SPEN	Q13153	PAK1	S3014	P3008Q	3008	Missense	distal	-6	no	22.994	23.800	EPSD	COSMIC;GDSC;CCLE	19.028	Up-regulation
STE_STE20_PAKA_PAK1_ST	Q96T58	SPEN	Q13153	PAK1	S3029	G3032R	3032	Missense	distal	3	no	22.126	19.541	EPSD	COSMIC	19.028	Down-regulation
STE_STE20_PAKA_PAK1_ST	Q96T58	SPEN	Q13153	PAK1	S3029	A3023V	3023	Missense	distal	-6	no	22.126	21.340	EPSD	COSMIC	19.028	Down-regulation
STE_STE20_PAKA_PAK1_ST	Q96T58	SPEN	Q13153	PAK1	S3029	S3035L	3035	Missense	distal	6	no	22.126	22.398	EPSD	COSMIC	19.028	Up-regulation
STE_STE20_PAKA_PAK1_ST	Q96T58	SPEN	Q13153	PAK1	S3035	G3032R	3032	Missense	distal	-3	no	18.975	26.852	EPSD	COSMIC	19.028	Gain
STE_STE20_PAKA_PAK1_ST	Q96T58	SPEN	Q13153	PAK1	S3035	P3037A	3037	Missense	proximal	2	no	18.975	19.234	EPSD	COSMIC	19.028	Gain
STE_STE20_PAKA_PAK1_ST	Q96T58	SPEN	Q13153	PAK1	T3139	R3136C	3136	Missense	distal	-3	no	20.528	0.572	EPSD	COSMIC	19.028	Loss
STE_STE20_PAKA_PAK1_ST	Q96T58	SPEN	Q13153	PAK1	T3139	P3140S	3140	Missense	proximal	1	no	20.528	20.644	EPSD	COSMIC	19.028	Up-regulation
STE_STE20_PAKA_PAK1_ST	Q96T58	SPEN	Q13153	PAK1	S3430	V3437F	3437	Missense	distal	7	no	21.419	21.518	EPSD	COSMIC	19.028	Up-regulation
STE_STE20_PAKA_PAK1_ST	Q96T58	SPEN	Q13153	PAK1	S3430	P3428S	3428	Missense	proximal	-2	no	21.419	16.791	EPSD	COSMIC	19.028	Loss
STE_STE20_PAKA_PAK1_ST	Q96T58	SPEN	Q13153	PAK1	S3486	S3492P	3492	Missense	distal	6	no	21.864	22.112	EPSD;PhosphoSitePlus	COSMIC	19.028	Up-regulation
STE_STE20_PAKA_PAK1_ST	Q96T58	SPEN	Q13153	PAK1	S3486	S3492F	3492	Missense	distal	6	no	21.864	22.240	EPSD;PhosphoSitePlus	COSMIC	19.028	Up-regulation
STE_STE20_PAKA_PAK1_ST	Q96T58	SPEN	Q13153	PAK1	T3568	A3564G	3564	Missense	distal	-4	no	24.389	23.872	PhosphoSitePlus;EPSD	COSMIC	19.028	Down-regulation
STE_STE20_PAKA_PAK1_ST	Q96T58	SPEN	Q13153	PAK1	T3568	R3565Q	3565	Missense	distal	-3	no	24.389	15.664	PhosphoSitePlus;EPSD	COSMIC	19.028	Loss
STE_STE20_PAKA_PAK1_ST	Q96T58	SPEN	Q13153	PAK1	T3568	G3562R	3562	Missense	distal	-6	no	24.389	26.685	PhosphoSitePlus;EPSD	COSMIC	19.028	Up-regulation
STE_STE20_PAKA_PAK1_ST	O14965	AURKA	Q13153	PAK1	S53	S54F	54	Missense	proximal	1	no	18.999	19.260	EPSD	COSMIC	19.028	Gain
STE_STE20_PAKA_PAK1_ST	O14965	AURKA	Q13153	PAK1	S53	Q55L	55	Missense	proximal	2	no	18.999	19.862	EPSD	COSMIC	19.028	Gain
STE_STE20_PAKA_PAK1_ST	O14965	AURKA	Q13153	PAK1	S67	K63N	63	Missense	distal	-4	no	19.585	18.875	EPSD	COSMIC	19.028	Loss
STE_STE20_PAKA_PAK1_ST	O14965	AURKA	Q13153	PAK1	S67	H68D	68	Missense	proximal	1	no	19.585	19.545	EPSD	COSMIC	19.028	Down-regulation
STE_STE20_PAKA_PAK1_ST	O14965	AURKA	Q13153	PAK1	T287	R285M	285	Missense	proximal	-2	no	19.536	15.297	EPSD	COSMIC	19.028	Loss
STE_STE20_PAKA_PAK1_ST	O14965	AURKA	Q13153	PAK1	T287	G291D	291	Missense	distal	4	no	19.536	19.078	EPSD	COSMIC	19.028	Down-regulation
STE_STE20_PAKA_PAK1_ST	O14965	AURKA	Q13153	PAK1	T287	T287I	287	Missense	central	0	yes	19.536	0.000	EPSD	COSMIC	19.028	Loss
STE_STE20_PAKA_PAK1_ST	O14965	AURKA	Q13153	PAK1	T287	T287A	287	Missense	central	0	yes	19.536	0.000	EPSD	COSMIC	19.028	Loss
STE_STE20_PAKA_PAK1_ST	O14965	AURKA	Q13153	PAK1	T287	C290F	290	Missense	distal	3	no	19.536	18.962	EPSD	COSMIC	19.028	Loss
STE_STE20_PAKA_PAK1_ST	O14965	AURKA	Q13153	PAK1	T288	R285M	285	Missense	distal	-3	no	27.239	19.669	EPSD;PhosphoSitePlus	COSMIC	19.028	Down-regulation
STE_STE20_PAKA_PAK1_ST	O14965	AURKA	Q13153	PAK1	T288	G291D	291	Missense	distal	3	no	27.239	25.938	EPSD;PhosphoSitePlus	COSMIC	19.028	Down-regulation
STE_STE20_PAKA_PAK1_ST	O14965	AURKA	Q13153	PAK1	T288	T287I	287	Missense	proximal	-1	no	27.239	26.383	EPSD;PhosphoSitePlus	COSMIC	19.028	Down-regulation
STE_STE20_PAKA_PAK1_ST	O14965	AURKA	Q13153	PAK1	T288	T287A	287	Missense	proximal	-1	no	27.239	24.209	EPSD;PhosphoSitePlus	COSMIC	19.028	Down-regulation
STE_STE20_PAKA_PAK1_ST	O14965	AURKA	Q13153	PAK1	T288	C290F	290	Missense	proximal	2	no	27.239	26.690	EPSD;PhosphoSitePlus	COSMIC	19.028	Down-regulation
STE_STE20_PAKA_PAK1_ST	P16949	STMN1	Q13153	PAK1	S16	R14C	14	Missense	proximal	-2	no	26.353	13.632	EPSD;PhosphoSitePlus	COSMIC	19.028	Loss
STE_STE20_PAKA_PAK1_ST	P16949	STMN1	Q13153	PAK1	S16	Q18E	18	Missense	proximal	2	no	26.353	26.430	EPSD;PhosphoSitePlus	COSMIC	19.028	Up-regulation
STE_STE20_PAKA_PAK1_ST	P16949	STMN1	Q13153	PAK1	S38	D44N	44	Missense	distal	6	no	19.215	19.360	PhosphoSitePlus;EPSD	COSMIC	19.028	Up-regulation
STE_STE20_PAKA_PAK1_ST	P16949	STMN1	Q13153	PAK1	S38	P36L	36	Missense	proximal	-2	no	19.215	14.176	PhosphoSitePlus;EPSD	COSMIC	19.028	Loss
STE_STE20_PAKA_PAK1_ST	P16949	STMN1	Q13153	PAK1	S46	D44N	44	Missense	proximal	-2	no	22.410	23.151	EPSD	COSMIC	19.028	Up-regulation
STE_STE20_PAKA_PAK1_ST	P16949	STMN1	Q13153	PAK1	S63	R61S	61	Missense	proximal	-2	no	30.985	22.832	EPSD	COSMIC	19.028	Down-regulation
STE_STE20_PAKA_PAK1_ST	P35240	NF2	Q13153	PAK1	T189	E186D	186	Missense	distal	-3	no	11.247	19.269	EPSD	COSMIC	19.028	Gain
STE_STE20_PAKA_PAK1_ST	P35240	NF2	Q13153	PAK1	S255	R262Q	262	Missense	distal	7	no	21.639	21.635	EPSD	COSMIC	19.028	Down-regulation
STE_STE20_PAKA_PAK1_ST	P35240	NF2	Q13153	PAK1	S255	K253N	253	Missense	proximal	-2	no	21.639	20.082	EPSD	COSMIC	19.028	Down-regulation
STE_STE20_PAKA_PAK1_ST	P35240	NF2	Q13153	PAK1	S255	P257L	257	Missense	proximal	2	no	21.639	21.807	EPSD	COSMIC	19.028	Up-regulation
STE_STE20_PAKA_PAK1_ST	P35240	NF2	Q13153	PAK1	S255	P257Q	257	Missense	proximal	2	no	21.639	20.944	EPSD	COSMIC	19.028	Down-regulation
STE_STE20_PAKA_PAK1_ST	P35240	NF2	Q13153	PAK1	S255	R249C	249	Missense	distal	-6	no	21.639	17.934	EPSD	COSMIC	19.028	Loss
STE_STE20_PAKA_PAK1_ST	P35240	NF2	Q13153	PAK1	S255	R249H	249	Missense	distal	-6	no	21.639	20.781	EPSD	COSMIC	19.028	Down-regulation
STE_STE20_PAKA_PAK1_ST	P35240	NF2	Q13153	PAK1	S255	R249P	249	Missense	distal	-6	no	21.639	19.571	EPSD	COSMIC	19.028	Down-regulation
STE_STE20_PAKA_PAK1_ST	P35240	NF2	Q13153	PAK1	S265	R262Q	262	Missense	distal	-3	no	19.418	10.694	EPSD	COSMIC	19.028	Loss
STE_STE20_PAKA_PAK1_ST	P35240	NF2	Q13153	PAK1	S265	E270D	270	Missense	distal	5	no	19.418	19.425	EPSD	COSMIC	19.028	Up-regulation
STE_STE20_PAKA_PAK1_ST	P35240	NF2	Q13153	PAK1	S315	S315Y	315	Missense	central	0	yes	19.055	0.000	EPSD	COSMIC	19.028	Loss
STE_STE20_PAKA_PAK1_ST	P35240	NF2	Q13153	PAK1	S315	D314N	314	Missense	proximal	-1	no	19.055	16.878	EPSD	COSMIC	19.028	Loss
STE_STE20_PAKA_PAK1_ST	P35240	NF2	Q13153	PAK1	S315	Q319H	319	Missense	distal	4	no	19.055	19.630	EPSD	COSMIC	19.028	Up-regulation
STE_STE20_PAKA_PAK1_ST	P35240	NF2	Q13153	PAK1	S315	Q320R	320	Missense	distal	5	no	19.055	19.058	EPSD	COSMIC	19.028	Up-regulation
STE_STE20_PAKA_PAK1_ST	P35240	NF2	Q13153	PAK1	S315	K322I	322	Missense	distal	7	no	19.055	19.053	EPSD	COSMIC	19.028	Down-regulation
STE_STE20_PAKA_PAK1_ST	P35240	NF2	Q13153	PAK1	S315	R309C	309	Missense	distal	-6	no	19.055	15.350	EPSD	COSMIC	19.028	Loss
STE_STE20_PAKA_PAK1_ST	P35240	NF2	Q13153	PAK1	S315	R309H	309	Missense	distal	-6	no	19.055	18.197	EPSD	COSMIC	19.028	Loss
STE_STE20_PAKA_PAK1_ST	P35240	NF2	Q13153	PAK1	S315	R310C	310	Missense	distal	-5	no	19.055	19.811	EPSD	COSMIC	19.028	Up-regulation
STE_STE20_PAKA_PAK1_ST	P35240	NF2	Q13153	PAK1	S315	R310H	310	Missense	distal	-5	no	19.055	19.502	EPSD	COSMIC	19.028	Up-regulation
STE_STE20_PAKA_PAK1_ST	P35240	NF2	Q13153	PAK1	S518	T512S	512	Missense	distal	-6	no	27.300	26.317	PhosphoSitePlus	COSMIC	19.028	Down-regulation
STE_STE20_PAKA_PAK1_ST	P35240	NF2	Q13153	PAK1	S518	M514V	514	Missense	distal	-4	no	27.300	27.403	PhosphoSitePlus	COSMIC	19.028	Up-regulation
STE_STE20_PAKA_PAK1_ST	P35240	NF2	Q13153	PAK1	S518	S518F	518	Missense	central	0	yes	27.300	0.000	PhosphoSitePlus	COSMIC	19.028	Loss
STE_STE20_PAKA_PAK1_ST	P35240	NF2	Q13153	PAK1	S518	D511H	511	Missense	distal	-7	no	27.300	26.780	PhosphoSitePlus	COSMIC	19.028	Down-regulation
STE_STE20_PAKA_PAK1_ST	P35240	NF2	Q13153	PAK1	S518	E520D	520	Missense	proximal	2	no	27.300	27.610	PhosphoSitePlus	COSMIC	19.028	Up-regulation
STE_STE20_PAKA_PAK1_ST	P35240	NF2	Q13153	PAK1	S518	E522K	522	Missense	distal	4	no	27.300	27.448	PhosphoSitePlus	COSMIC	19.028	Up-regulation
STE_STE20_PAKA_PAK1_ST	P35240	NF2	Q13153	PAK1	S518	E522Q	522	Missense	distal	4	no	27.300	26.735	PhosphoSitePlus	COSMIC	19.028	Down-regulation
STE_STE20_PAKA_PAK1_ST	P35240	NF2	Q13153	PAK1	S518	L517V	517	Missense	proximal	-1	no	27.300	24.432	PhosphoSitePlus	COSMIC	19.028	Down-regulation
STE_STE20_PAKA_PAK1_ST	Q9UQ80	PA2G4	Q13153	PAK1	T261	T261A	261	Missense	central	0	yes	23.041	0.000	PhosphoSitePlus	COSMIC	19.028	Loss
STE_STE20_PAKA_PAK1_ST	Q9UQ80	PA2G4	Q13153	PAK1	T261	G256R	256	Missense	distal	-5	no	23.041	22.097	PhosphoSitePlus	COSMIC	19.028	Down-regulation
STE_STE20_PAKA_PAK1_ST	Q9UQ80	PA2G4	Q13153	PAK1	S262	G256R	256	Missense	distal	-6	no	16.774	19.071	EPSD	COSMIC	19.028	Gain
STE_STE20_PAKA_PAK1_ST	Q9UQ80	PA2G4	Q13153	PAK1	T334	G329C	329	Missense	distal	-5	no	22.274	22.085	EPSD	COSMIC	19.028	Down-regulation
STE_STE20_PAKA_PAK1_ST	Q9UQ80	PA2G4	Q13153	PAK1	T334	R332Q	332	Missense	proximal	-2	no	22.274	13.067	EPSD	COSMIC	19.028	Loss
STE_STE20_PAKA_PAK1_ST	Q9UQ80	PA2G4	Q13153	PAK1	S335	G329C	329	Missense	distal	-6	no	20.462	19.054	EPSD	COSMIC	19.028	Down-regulation
STE_STE20_PAKA_PAK1_ST	Q9UQ80	PA2G4	Q13153	PAK1	S335	R332Q	332	Missense	distal	-3	no	20.462	11.738	EPSD	COSMIC	19.028	Loss
STE_STE20_PAKA_PAK1_ST	Q13761	RUNX3	Q13153	PAK1	T14	S17F	17	Missense	distal	3	no	27.809	28.390	EPSD	COSMIC	19.028	Up-regulation
STE_STE20_PAKA_PAK1_ST	Q13761	RUNX3	Q13153	PAK1	S54	E51Q	51	Missense	distal	-3	no	14.365	20.619	EPSD	COSMIC	19.028	Gain
STE_STE20_PAKA_PAK1_ST	Q13761	RUNX3	Q13153	PAK1	S71	D70N	70	Missense	proximal	-1	no	22.360	20.183	EPSD	COSMIC	19.028	Down-regulation
STE_STE20_PAKA_PAK1_ST	Q13761	RUNX3	Q13153	PAK1	S71	R68C	68	Missense	distal	-3	no	22.360	2.404	EPSD	COSMIC	19.028	Loss
STE_STE20_PAKA_PAK1_ST	Q13761	RUNX3	Q13153	PAK1	S71	R68H	68	Missense	distal	-3	no	22.360	16.289	EPSD	COSMIC	19.028	Loss
STE_STE20_PAKA_PAK1_ST	Q13761	RUNX3	Q13153	PAK1	S71	C76F	76	Missense	distal	5	no	22.360	22.344	EPSD	COSMIC	19.028	Down-regulation
STE_STE20_PAKA_PAK1_ST	Q13761	RUNX3	Q13153	PAK1	S71	N73Y	73	Missense	proximal	2	no	22.360	24.264	EPSD	COSMIC	19.028	Up-regulation
STE_STE20_PAKA_PAK1_ST	Q13761	RUNX3	Q13153	PAK1	S71	E65G	65	Missense	distal	-6	no	22.360	20.965	EPSD	COSMIC	19.028	Down-regulation
STE_STE20_PAKA_PAK1_ST	Q13761	RUNX3	Q13153	PAK1	T153	K148N	148	Missense	distal	-5	no	20.839	21.358	EPSD	COSMIC	19.028	Up-regulation
STE_STE20_PAKA_PAK1_ST	Q13761	RUNX3	Q13153	PAK1	T153	R146P	146	Missense	distal	-7	no	20.839	20.012	EPSD	COSMIC	19.028	Down-regulation
STE_STE20_PAKA_PAK1_ST	Q13761	RUNX3	Q13153	PAK1	T153	L152M	152	Missense	proximal	-1	no	20.839	18.049	EPSD	COSMIC	19.028	Loss
STE_STE20_PAKA_PAK1_ST	Q13761	RUNX3	Q13153	PAK1	T153	P160T	160	Missense	distal	7	no	20.839	20.490	EPSD	COSMIC	19.028	Down-regulation
STE_STE20_PAKA_PAK1_ST	Q13761	RUNX3	Q13153	PAK1	T153	F157L	157	Missense	distal	4	no	20.839	20.168	EPSD	COSMIC	19.028	Down-regulation
STE_STE20_PAKA_PAK1_ST	Q13761	RUNX3	Q13153	PAK1	T209	R205C	205	Missense	distal	-4	no	22.291	21.331	PhosphoSitePlus	COSMIC	19.028	Down-regulation
STE_STE20_PAKA_PAK1_ST	Q13761	RUNX3	Q13153	PAK1	T209	P210L	210	Missense	proximal	1	no	22.291	22.578	PhosphoSitePlus	COSMIC	19.028	Up-regulation
STE_STE20_PAKA_PAK1_ST	Q13761	RUNX3	Q13153	PAK1	T209	V208G	208	Missense	proximal	-1	no	22.291	21.223	PhosphoSitePlus	COSMIC	19.028	Down-regulation
STE_STE20_PAKA_PAK1_ST	Q13761	RUNX3	Q13153	PAK1	T209	R216Q	216	Missense	distal	7	no	22.291	22.286	PhosphoSitePlus	COSMIC	19.028	Down-regulation
STE_STE20_PAKA_PAK1_ST	Q13761	RUNX3	Q13153	PAK1	T209	R203L	203	Missense	distal	-6	no	22.291	20.069	PhosphoSitePlus	COSMIC	19.028	Down-regulation
STE_STE20_PAKA_PAK1_ST	Q13761	RUNX3	Q13153	PAK1	T209	S214G	214	Missense	distal	5	no	22.291	22.322	PhosphoSitePlus	COSMIC	19.028	Up-regulation
STE_STE20_PAKA_PAK1_ST	Q13761	RUNX3	Q13153	PAK1	T209	P215L	215	Missense	distal	6	no	22.291	22.315	PhosphoSitePlus	COSMIC	19.028	Up-regulation
STE_STE20_PAKA_PAK1_ST	Q13761	RUNX3	Q13153	PAK1	T209	R205H	205	Missense	distal	-4	no	22.291	21.856	PhosphoSitePlus	COSMIC	19.028	Down-regulation
STE_STE20_PAKA_PAK1_ST	Q13761	RUNX3	Q13153	PAK1	S226	S223R	223	Missense	distal	-3	no	13.736	22.407	EPSD	COSMIC	19.028	Gain
STE_STE20_PAKA_PAK1_ST	Q13761	RUNX3	Q13153	PAK1	S301	A299T	299	Missense	proximal	-2	no	16.180	19.137	EPSD	COSMIC	19.028	Gain
STE_STE20_PAKA_PAK1_ST	P53667	LIMK1	Q13153	PAK1	S298	R295W	295	Missense	distal	-3	no	19.466	11.906	EPSD	COSMIC	19.028	Loss
STE_STE20_PAKA_PAK1_ST	P53667	LIMK1	Q13153	PAK1	S323	V326I	326	Missense	distal	3	no	19.027	19.108	EPSD	COSMIC	19.028	Gain
STE_STE20_PAKA_PAK1_ST	P53667	LIMK1	Q13153	PAK1	S323	E322D	322	Missense	proximal	-1	no	19.027	20.332	EPSD	COSMIC	19.028	Gain
STE_STE20_PAKA_PAK1_ST	P53667	LIMK1	Q13153	PAK1	S337	P336T	336	Missense	proximal	-1	no	17.797	21.520	EPSD	COSMIC	19.028	Gain
STE_STE20_PAKA_PAK1_ST	P53667	LIMK1	Q13153	PAK1	S430	S435I	435	Missense	distal	5	no	22.952	22.959	EPSD	COSMIC	19.028	Up-regulation
STE_STE20_PAKA_PAK1_ST	P53667	LIMK1	Q13153	PAK1	S534	D531Y	531	Missense	distal	-3	no	20.848	22.037	EPSD	COSMIC;GDSC;CCLE	19.028	Up-regulation
STE_STE20_PAKA_PAK1_ST	P53667	LIMK1	Q13153	PAK1	S534	E528K	528	Missense	distal	-6	no	20.848	19.692	EPSD	COSMIC;GDSC;CCLE	19.028	Down-regulation
STE_STE20_PAKA_PAK1_ST	P53667	LIMK1	Q13153	PAK1	S534	S534F	534	Missense	central	0	yes	20.848	0.000	EPSD	COSMIC;GDSC;CCLE	19.028	Loss
STE_STE20_PAKA_PAK1_ST	Q70Z35	PREX2	Q13153	PAK1	S901	K905N	905	Missense	distal	4	no	19.357	19.330	EPSD	COSMIC	19.028	Down-regulation
STE_STE20_PAKA_PAK1_ST	Q70Z35	PREX2	Q13153	PAK1	S901	S907Y	907	Missense	distal	6	no	19.357	20.001	EPSD	COSMIC	19.028	Up-regulation
STE_STE20_PAKA_PAK1_ST	Q70Z35	PREX2	Q13153	PAK1	S901	L896R	896	Missense	distal	-5	no	19.357	18.567	EPSD	COSMIC	19.028	Loss
STE_STE20_PAKA_PAK1_ST	Q70Z35	PREX2	Q13153	PAK1	S907	K905N	905	Missense	proximal	-2	no	23.618	22.061	EPSD	COSMIC	19.028	Down-regulation
STE_STE20_PAKA_PAK1_ST	Q70Z35	PREX2	Q13153	PAK1	S907	S907Y	907	Missense	central	0	yes	23.618	0.000	EPSD	COSMIC	19.028	Loss
STE_STE20_PAKA_PAK1_ST	Q70Z35	PREX2	Q13153	PAK1	T952	P948L	948	Missense	distal	-4	no	19.141	19.347	EPSD	COSMIC	19.028	Up-regulation
STE_STE20_PAKA_PAK1_ST	Q70Z35	PREX2	Q13153	PAK1	T952	S953T	953	Missense	proximal	1	no	19.141	19.551	EPSD	COSMIC	19.028	Up-regulation
STE_STE20_PAKA_PAK1_ST	Q70Z35	PREX2	Q13153	PAK1	T952	F958V	958	Missense	distal	6	no	19.141	19.102	EPSD	COSMIC	19.028	Down-regulation
STE_STE20_PAKA_PAK1_ST	Q70Z35	PREX2	Q13153	PAK1	T952	P948S	948	Missense	distal	-4	no	19.141	19.193	EPSD	COSMIC	19.028	Up-regulation
STE_STE20_PAKA_PAK1_ST	Q70Z35	PREX2	Q13153	PAK1	T952	S956C	956	Missense	distal	4	no	19.141	20.530	EPSD	COSMIC	19.028	Up-regulation
STE_STE20_PAKA_PAK1_ST	Q70Z35	PREX2	Q13153	PAK1	S1065	I1069M	1069	Missense	distal	4	no	31.089	31.293	EPSD	COSMIC	19.028	Up-regulation
STE_STE20_PAKA_PAK1_ST	Q70Z35	PREX2	Q13153	PAK1	S1065	D1072N	1072	Missense	distal	7	no	31.089	31.084	EPSD	COSMIC	19.028	Down-regulation
STE_STE20_PAKA_PAK1_ST	Q70Z35	PREX2	Q13153	PAK1	S1065	P1070T	1070	Missense	distal	5	no	31.089	31.062	EPSD	COSMIC	19.028	Down-regulation
STE_STE20_PAKA_PAK1_ST	Q70Z35	PREX2	Q13153	PAK1	S1107	S1113R	1113	Missense	distal	6	no	22.274	22.009	PhosphoSitePlus	COSMIC	19.028	Down-regulation
STE_STE20_PAKA_PAK1_ST	Q02750	MAP2K1	Q13153	PAK1	T55	K57E	57	Missense	proximal	2	no	19.774	19.471	EPSD	COSMIC	19.028	Down-regulation
STE_STE20_PAKA_PAK1_ST	Q02750	MAP2K1	Q13153	PAK1	T55	R49L	49	Missense	distal	-6	no	19.774	17.553	EPSD	COSMIC	19.028	Loss
STE_STE20_PAKA_PAK1_ST	Q02750	MAP2K1	Q13153	PAK1	T55	F53Y	53	Missense	proximal	-2	no	19.774	21.052	EPSD	COSMIC	19.028	Up-regulation
STE_STE20_PAKA_PAK1_ST	Q02750	MAP2K1	Q13153	PAK1	T55	R49C	49	Missense	distal	-6	no	19.774	16.069	EPSD	COSMIC;GDSC;CCLE	19.028	Loss
STE_STE20_PAKA_PAK1_ST	Q02750	MAP2K1	Q13153	PAK1	T55	L54P	54	Missense	proximal	-1	no	19.774	15.583	EPSD	COSMIC	19.028	Loss
STE_STE20_PAKA_PAK1_ST	Q02750	MAP2K1	Q13153	PAK1	T55	Q58H	58	Missense	distal	3	no	19.774	19.529	EPSD	COSMIC	19.028	Down-regulation
STE_STE20_PAKA_PAK1_ST	Q02750	MAP2K1	Q13153	PAK1	T55	T55P	55	Missense	central	0	yes	19.774	0.000	EPSD	COSMIC	19.028	Loss
STE_STE20_PAKA_PAK1_ST	Q02750	MAP2K1	Q13153	PAK1	T55	E51G	51	Missense	distal	-4	no	19.774	19.173	EPSD	COSMIC	19.028	Down-regulation
STE_STE20_PAKA_PAK1_ST	Q02750	MAP2K1	Q13153	PAK1	T55	V60E	60	Missense	distal	5	no	19.774	19.761	EPSD	COSMIC;GDSC;CCLE	19.028	Down-regulation
STE_STE20_PAKA_PAK1_ST	Q02750	MAP2K1	Q13153	PAK1	T55	V60M	60	Missense	distal	5	no	19.774	19.790	EPSD	COSMIC	19.028	Up-regulation
STE_STE20_PAKA_PAK1_ST	Q02750	MAP2K1	Q13153	PAK1	T292	P293S	293	Missense	proximal	1	no	27.677	27.794	EPSD	COSMIC	19.028	Up-regulation
STE_STE20_PAKA_PAK1_ST	Q02750	MAP2K1	Q13153	PAK1	T292	R291K	291	Missense	proximal	-1	no	27.677	27.144	EPSD	COSMIC	19.028	Down-regulation
STE_STE20_PAKA_PAK1_ST	Q02750	MAP2K1	Q13153	PAK1	S298	G301E	301	Missense	distal	3	no	33.212	30.699	PhosphoSitePlus	COSMIC	19.028	Down-regulation
STE_STE20_PAKA_PAK1_ST	Q02750	MAP2K1	Q13153	PAK1	S298	P293S	293	Missense	distal	-5	no	33.212	32.350	PhosphoSitePlus	COSMIC	19.028	Down-regulation
STE_STE20_PAKA_PAK1_ST	Q02750	MAP2K1	Q13153	PAK1	S298	R291K	291	Missense	distal	-7	no	33.212	32.593	PhosphoSitePlus	COSMIC	19.028	Down-regulation
STE_STE20_PAKA_PAK1_ST	Q02750	MAP2K1	Q13153	PAK1	S299	P293S	293	Missense	distal	-6	no	18.971	19.029	EPSD	COSMIC	19.028	Gain
STE_STE20_PAKA_PAK1_ST	Q13363	CTBP1	Q13153	PAK1	S100	D106E	106	Missense	distal	6	no	19.378	19.234	EPSD	COSMIC	19.028	Down-regulation
STE_STE20_PAKA_PAK1_ST	Q13363	CTBP1	Q13153	PAK1	S100	D103V	103	Missense	distal	3	no	19.378	19.392	EPSD	COSMIC	19.028	Up-regulation
STE_STE20_PAKA_PAK1_ST	Q13363	CTBP1	Q13153	PAK1	T144	A149V	149	Missense	distal	5	no	19.905	19.906	EPSD	COSMIC	19.028	Up-regulation
STE_STE20_PAKA_PAK1_ST	Q13363	CTBP1	Q13153	PAK1	T144	R141W	141	Missense	distal	-3	no	19.905	12.345	EPSD	COSMIC	19.028	Loss
STE_STE20_PAKA_PAK1_ST	Q13363	CTBP1	Q13153	PAK1	S158	E160K	160	Missense	proximal	2	no	24.346	24.649	PhosphoSitePlus	COSMIC	19.028	Up-regulation
STE_STE20_PAKA_PAK1_ST	Q13363	CTBP1	Q13153	PAK1	S158	E152G	152	Missense	distal	-6	no	24.346	22.951	PhosphoSitePlus	COSMIC	19.028	Down-regulation
STE_STE20_PAKA_PAK1_ST	Q13363	CTBP1	Q13153	PAK1	S158	E164K	164	Missense	distal	6	no	24.346	24.661	PhosphoSitePlus	COSMIC;CCLE	19.028	Up-regulation
STE_STE20_PAKA_PAK1_ST	Q13363	CTBP1	Q13153	PAK1	S300	P296T	296	Missense	distal	-4	no	18.800	19.365	EPSD	COSMIC	19.028	Gain
STE_STE20_PAKA_PAK1_ST	Q8IYU2	HACE1	Q13153	PAK1	S385	M379T	379	Missense	distal	-6	no	27.095	28.468	PhosphoSitePlus	COSMIC	19.028	Up-regulation
STE_STE20_PAKA_PAK1_ST	Q8IYU2	HACE1	Q13153	PAK1	S385	D384N	384	Missense	proximal	-1	no	27.095	24.918	PhosphoSitePlus	COSMIC	19.028	Down-regulation
STE_STE20_PAKA_PAK1_ST	Q8IYU2	HACE1	Q13153	PAK1	T386	M379T	379	Missense	distal	-7	no	19.413	21.014	EPSD	COSMIC	19.028	Up-regulation
STE_STE20_PAKA_PAK1_ST	Q8IYU2	HACE1	Q13153	PAK1	T386	D384N	384	Missense	proximal	-2	no	19.413	20.154	EPSD	COSMIC	19.028	Up-regulation
STE_STE20_PAKA_PAK1_ST	P03372	ESR1	Q13153	PAK1	S47	D45N	45	Missense	proximal	-2	no	18.480	19.221	EPSD	COSMIC	19.028	Gain
STE_STE20_PAKA_PAK1_ST	P03372	ESR1	Q13153	PAK1	S154	A148E	148	Missense	distal	-6	no	26.206	26.257	EPSD	COSMIC	19.028	Up-regulation
STE_STE20_PAKA_PAK1_ST	P03372	ESR1	Q13153	PAK1	S154	R151K	151	Missense	distal	-3	no	26.206	25.019	EPSD	COSMIC	19.028	Down-regulation
STE_STE20_PAKA_PAK1_ST	P03372	ESR1	Q13153	PAK1	S154	P147Q	147	Missense	distal	-7	no	26.206	26.509	EPSD	COSMIC	19.028	Up-regulation
STE_STE20_PAKA_PAK1_ST	P03372	ESR1	Q13153	PAK1	S154	R158C	158	Missense	distal	4	no	26.206	28.199	EPSD	COSMIC	19.028	Up-regulation
STE_STE20_PAKA_PAK1_ST	P03372	ESR1	Q13153	PAK1	S154	Q159L	159	Missense	distal	5	no	26.206	26.222	EPSD	COSMIC	19.028	Up-regulation
STE_STE20_PAKA_PAK1_ST	P03372	ESR1	Q13153	PAK1	S154	R157Q	157	Missense	distal	3	no	26.206	26.705	EPSD	COSMIC	19.028	Up-regulation
STE_STE20_PAKA_PAK1_ST	P03372	ESR1	Q13153	PAK1	S154	N156T	156	Missense	proximal	2	no	26.206	25.119	EPSD	COSMIC	19.028	Down-regulation
STE_STE20_PAKA_PAK1_ST	P03372	ESR1	Q13153	PAK1	S154	G160D	160	Missense	distal	6	no	26.206	25.883	EPSD	COSMIC	19.028	Down-regulation
STE_STE20_PAKA_PAK1_ST	P03372	ESR1	Q13153	PAK1	S154	P152S	152	Missense	proximal	-2	no	26.206	21.578	EPSD	COSMIC	19.028	Down-regulation
STE_STE20_PAKA_PAK1_ST	P03372	ESR1	Q13153	PAK1	S154	P152L	152	Missense	proximal	-2	no	26.206	21.166	EPSD	COSMIC	19.028	Down-regulation
STE_STE20_PAKA_PAK1_ST	P03372	ESR1	Q13153	PAK1	S167	D170Y	170	Missense	distal	3	no	18.361	20.697	EPSD	COSMIC	19.028	Gain
STE_STE20_PAKA_PAK1_ST	P03372	ESR1	Q13153	PAK1	S167	G160D	160	Missense	distal	-7	no	18.361	19.037	EPSD	COSMIC	19.028	Gain
STE_STE20_PAKA_PAK1_ST	P03372	ESR1	Q13153	PAK1	S212	K206T	206	Missense	distal	-6	no	20.050	21.081	EPSD	COSMIC	19.028	Up-regulation
STE_STE20_PAKA_PAK1_ST	P03372	ESR1	Q13153	PAK1	S212	R211I	211	Missense	proximal	-1	no	20.050	18.594	EPSD	COSMIC	19.028	Loss
STE_STE20_PAKA_PAK1_ST	P03372	ESR1	Q13153	PAK1	S212	Q214E	214	Missense	proximal	2	no	20.050	20.128	EPSD	COSMIC	19.028	Up-regulation
STE_STE20_PAKA_PAK1_ST	P03372	ESR1	Q13153	PAK1	S212	R211S	211	Missense	proximal	-1	no	20.050	18.970	EPSD	COSMIC	19.028	Loss
STE_STE20_PAKA_PAK1_ST	P03372	ESR1	Q13153	PAK1	S212	I213N	213	Missense	proximal	1	no	20.050	19.896	EPSD	COSMIC	19.028	Down-regulation
STE_STE20_PAKA_PAK1_ST	P03372	ESR1	Q13153	PAK1	S236	R241G	241	Missense	distal	5	no	25.537	25.568	EPSD	COSMIC	19.028	Up-regulation
STE_STE20_PAKA_PAK1_ST	P03372	ESR1	Q13153	PAK1	S236	R241W	241	Missense	distal	5	no	25.537	25.568	EPSD	COSMIC	19.028	Up-regulation
STE_STE20_PAKA_PAK1_ST	P03372	ESR1	Q13153	PAK1	S236	R233G	233	Missense	distal	-3	no	25.537	17.660	EPSD	COSMIC	19.028	Loss
STE_STE20_PAKA_PAK1_ST	P03372	ESR1	Q13153	PAK1	S236	C237Y	237	Missense	proximal	1	no	25.537	25.489	EPSD	COSMIC	19.028	Down-regulation
STE_STE20_PAKA_PAK1_ST	P03372	ESR1	Q13153	PAK1	S236	Q238H	238	Missense	proximal	2	no	25.537	25.520	EPSD	COSMIC;CCLE	19.028	Down-regulation
STE_STE20_PAKA_PAK1_ST	P03372	ESR1	Q13153	PAK1	S236	R243L	243	Missense	distal	7	no	25.537	25.685	EPSD	COSMIC	19.028	Up-regulation
STE_STE20_PAKA_PAK1_ST	P03372	ESR1	Q13153	PAK1	S305	K303R	303	Missense	proximal	-2	no	23.459	27.496	PhosphoSitePlus	COSMIC	19.028	Up-regulation
STE_STE20_PAKA_PAK1_ST	P03372	ESR1	Q13153	PAK1	S305	K299R	299	Missense	distal	-6	no	23.459	25.516	PhosphoSitePlus	COSMIC	19.028	Up-regulation
STE_STE20_PAKA_PAK1_ST	P03372	ESR1	Q13153	PAK1	S305	N304S	304	Missense	proximal	-1	no	23.459	26.265	PhosphoSitePlus	COSMIC	19.028	Up-regulation
STE_STE20_PAKA_PAK1_ST	P03372	ESR1	Q13153	PAK1	S305	R300C	300	Missense	distal	-5	no	23.459	24.214	PhosphoSitePlus	COSMIC;CCLE	19.028	Up-regulation
STE_STE20_PAKA_PAK1_ST	P03372	ESR1	Q13153	PAK1	S305	A307P	307	Missense	proximal	2	no	23.459	23.200	PhosphoSitePlus	COSMIC	19.028	Down-regulation
STE_STE20_PAKA_PAK1_ST	P03372	ESR1	Q13153	PAK1	S305	N304H	304	Missense	proximal	-1	no	23.459	24.538	PhosphoSitePlus	COSMIC	19.028	Up-regulation
STE_STE20_PAKA_PAK1_ST	P03372	ESR1	Q13153	PAK1	S554	G557R	557	Missense	distal	3	no	22.051	19.465	EPSD	COSMIC	19.028	Down-regulation
STE_STE20_PAKA_PAK1_ST	P03372	ESR1	Q13153	PAK1	S554	H550Y	550	Missense	distal	-4	no	22.051	21.495	EPSD	COSMIC	19.028	Down-regulation
STE_STE20_PAKA_PAK1_ST	P03372	ESR1	Q13153	PAK1	S554	L549P	549	Missense	distal	-5	no	22.051	22.152	EPSD	COSMIC	19.028	Up-regulation
STE_STE20_PAKA_PAK1_ST	P03372	ESR1	Q13153	PAK1	S554	V560M	560	Missense	distal	6	no	22.051	22.296	EPSD	COSMIC	19.028	Up-regulation
STE_STE20_PAKA_PAK1_ST	Q15746	MYLK	Q13153	PAK1	S16	S13F	13	Missense	distal	-3	no	16.218	19.730	EPSD	COSMIC;CCLE	19.028	Gain
STE_STE20_PAKA_PAK1_ST	Q15746	MYLK	Q13153	PAK1	S145	E150D	150	Missense	distal	5	no	22.803	22.810	EPSD	COSMIC	19.028	Up-regulation
STE_STE20_PAKA_PAK1_ST	Q15746	MYLK	Q13153	PAK1	S320	D327N	327	Missense	distal	7	no	19.864	19.860	EPSD	COSMIC	19.028	Down-regulation
STE_STE20_PAKA_PAK1_ST	Q15746	MYLK	Q13153	PAK1	S320	E323K	323	Missense	distal	3	no	19.864	19.965	EPSD	COSMIC	19.028	Up-regulation
STE_STE20_PAKA_PAK1_ST	Q15746	MYLK	Q13153	PAK1	S343	Q348K	348	Missense	distal	5	no	20.279	20.290	EPSD	COSMIC	19.028	Up-regulation
STE_STE20_PAKA_PAK1_ST	Q15746	MYLK	Q13153	PAK1	S343	S344F	344	Missense	proximal	1	no	20.279	20.539	EPSD	COSMIC	19.028	Up-regulation
STE_STE20_PAKA_PAK1_ST	Q15746	MYLK	Q13153	PAK1	S365	P359L	359	Missense	distal	-6	no	19.213	19.060	EPSD	COSMIC	19.028	Down-regulation
STE_STE20_PAKA_PAK1_ST	Q15746	MYLK	Q13153	PAK1	S609	Y611C	611	Missense	proximal	2	no	25.023	23.403	EPSD	COSMIC	19.028	Down-regulation
STE_STE20_PAKA_PAK1_ST	Q15746	MYLK	Q13153	PAK1	S609	K608T	608	Missense	proximal	-1	no	25.023	24.955	EPSD	COSMIC	19.028	Down-regulation
STE_STE20_PAKA_PAK1_ST	Q15746	MYLK	Q13153	PAK1	S827	E824K	824	Missense	distal	-3	no	8.666	22.458	EPSD	COSMIC	19.028	Gain
STE_STE20_PAKA_PAK1_ST	Q15746	MYLK	Q13153	PAK1	S848	G847W	847	Missense	proximal	-1	no	23.409	23.856	EPSD	COSMIC	19.028	Up-regulation
STE_STE20_PAKA_PAK1_ST	Q15746	MYLK	Q13153	PAK1	S947	Q949R	949	Missense	proximal	2	no	19.631	19.295	EPSD	COSMIC	19.028	Down-regulation
STE_STE20_PAKA_PAK1_ST	Q15746	MYLK	Q13153	PAK1	S947	E940K	940	Missense	distal	-7	no	19.631	18.903	EPSD	COSMIC	19.028	Loss
STE_STE20_PAKA_PAK1_ST	Q15746	MYLK	Q13153	PAK1	S947	P948S	948	Missense	proximal	1	no	19.631	19.748	EPSD	COSMIC;GDSC;CCLE	19.028	Up-regulation
STE_STE20_PAKA_PAK1_ST	Q15746	MYLK	Q13153	PAK1	S947	S947N	947	Missense	central	0	yes	19.631	0.000	EPSD	COSMIC	19.028	Loss
STE_STE20_PAKA_PAK1_ST	Q15746	MYLK	Q13153	PAK1	S1063	E1066K	1066	Missense	distal	3	no	19.809	19.910	EPSD	COSMIC	19.028	Up-regulation
STE_STE20_PAKA_PAK1_ST	Q15746	MYLK	Q13153	PAK1	S1063	K1068T	1068	Missense	distal	5	no	19.809	19.801	EPSD	COSMIC	19.028	Down-regulation
STE_STE20_PAKA_PAK1_ST	Q15746	MYLK	Q13153	PAK1	S1063	S1061P	1061	Missense	proximal	-2	no	19.809	24.437	EPSD	COSMIC	19.028	Up-regulation
STE_STE20_PAKA_PAK1_ST	Q15746	MYLK	Q13153	PAK1	S1208	R1205G	1205	Missense	distal	-3	no	28.909	21.033	EPSD	COSMIC	19.028	Down-regulation
STE_STE20_PAKA_PAK1_ST	Q15746	MYLK	Q13153	PAK1	S1209	R1205G	1205	Missense	distal	-4	no	20.433	19.546	EPSD	COSMIC	19.028	Down-regulation
STE_STE20_PAKA_PAK1_ST	Q15746	MYLK	Q13153	PAK1	S1570	I1563M	1563	Missense	distal	-7	no	21.141	20.336	EPSD	COSMIC	19.028	Down-regulation
STE_STE20_PAKA_PAK1_ST	Q15746	MYLK	Q13153	PAK1	S1570	G1572R	1572	Missense	proximal	2	no	21.141	19.607	EPSD	COSMIC	19.028	Down-regulation
STE_STE20_PAKA_PAK1_ST	Q15746	MYLK	Q13153	PAK1	S1759	A1762V	1762	Missense	distal	3	no	24.753	24.498	EPSD	COSMIC;GDSC;CCLE	19.028	Down-regulation
STE_STE20_PAKA_PAK1_ST	Q15746	MYLK	Q13153	PAK1	S1759	S1760Y	1760	Missense	proximal	1	no	24.753	24.664	EPSD	COSMIC	19.028	Down-regulation
STE_STE20_PAKA_PAK1_ST	Q15746	MYLK	Q13153	PAK1	S1760	A1762V	1762	Missense	proximal	2	no	25.701	25.771	EPSD	COSMIC;GDSC;CCLE	19.028	Up-regulation
STE_STE20_PAKA_PAK1_ST	Q15746	MYLK	Q13153	PAK1	S1760	S1760Y	1760	Missense	central	0	yes	25.701	0.000	EPSD	COSMIC	19.028	Loss
STE_STE20_PAKA_PAK1_ST	Q15746	MYLK	Q13153	PAK1	S1772	P1777S	1777	Missense	distal	5	no	20.841	20.813	PhosphoSitePlus	COSMIC	19.028	Down-regulation
STE_STE20_PAKA_PAK1_ST	Q15746	MYLK	Q13153	PAK1	S1773	P1777S	1777	Missense	distal	4	no	22.812	20.462	EPSD	COSMIC	19.028	Down-regulation
STE_STE20_PAKA_PAK1_ST	Q15746	MYLK	Q13153	PAK1	T1774	P1777S	1777	Missense	distal	3	no	21.034	18.653	EPSD	COSMIC	19.028	Loss
STE_STE20_PAKA_PAK1_ST	Q15746	MYLK	Q13153	PAK1	T1774	L1781F	1781	Missense	distal	7	no	21.034	21.102	EPSD	COSMIC	19.028	Up-regulation
STE_STE20_PAKA_PAK1_ST	Q15746	MYLK	Q13153	PAK1	S1788	D1791N	1791	Missense	distal	3	no	19.496	19.773	EPSD	COSMIC	19.028	Up-regulation
STE_STE20_PAKA_PAK1_ST	Q15746	MYLK	Q13153	PAK1	S1788	E1790K	1790	Missense	proximal	2	no	19.496	19.799	EPSD	COSMIC	19.028	Up-regulation
STE_STE20_PAKA_PAK1_ST	Q15746	MYLK	Q13153	PAK1	S1788	L1781F	1781	Missense	distal	-7	no	19.496	19.202	EPSD	COSMIC	19.028	Down-regulation
STE_STE20_PAKA_PAK1_ST	Q15746	MYLK	Q13153	PAK1	S1793	E1790K	1790	Missense	distal	-3	no	6.333	20.125	EPSD	COSMIC	19.028	Gain
STE_STE20_PAKA_PAK1_ST	P08670	VIM	Q13153	PAK1	S26	S27R	27	Missense	proximal	1	no	24.597	25.000	EPSD	COSMIC	19.028	Up-regulation
STE_STE20_PAKA_PAK1_ST	P08670	VIM	Q13153	PAK1	S27	S34P	34	Missense	distal	7	no	18.957	19.032	EPSD	COSMIC	19.028	Gain
STE_STE20_PAKA_PAK1_ST	P08670	VIM	Q13153	PAK1	S29	S27R	27	Missense	proximal	-2	no	13.692	21.845	EPSD	COSMIC	19.028	Gain
STE_STE20_PAKA_PAK1_ST	P08670	VIM	Q13153	PAK1	T35	R36H	36	Missense	proximal	1	no	19.576	19.314	EPSD	COSMIC	19.028	Down-regulation
STE_STE20_PAKA_PAK1_ST	P08670	VIM	Q13153	PAK1	T35	S34P	34	Missense	proximal	-1	no	19.576	16.332	EPSD	COSMIC	19.028	Loss
STE_STE20_PAKA_PAK1_ST	P08670	VIM	Q13153	PAK1	T37	S34P	34	Missense	distal	-3	no	16.288	19.277	EPSD	COSMIC	19.028	Gain
STE_STE20_PAKA_PAK1_ST	P08670	VIM	Q13153	PAK1	S39	R36H	36	Missense	distal	-3	no	23.474	17.402	EPSD	COSMIC	19.028	Loss
STE_STE20_PAKA_PAK1_ST	P08670	VIM	Q13153	PAK1	S39	S34P	34	Missense	distal	-5	no	23.474	24.335	EPSD	COSMIC	19.028	Up-regulation
STE_STE20_PAKA_PAK1_ST	P08670	VIM	Q13153	PAK1	S51	S55A	55	Missense	distal	4	no	20.183	21.158	EPSD	COSMIC	19.028	Up-regulation
STE_STE20_PAKA_PAK1_ST	P08670	VIM	Q13153	PAK1	S51	S51N	51	Missense	central	0	yes	20.183	0.000	EPSD	COSMIC	19.028	Loss
STE_STE20_PAKA_PAK1_ST	P08670	VIM	Q13153	PAK1	S51	S56Y	56	Missense	distal	5	no	20.183	20.215	EPSD	COSMIC	19.028	Up-regulation
STE_STE20_PAKA_PAK1_ST	P08670	VIM	Q13153	PAK1	S56	G59N	59	Missense	distal	3	no	22.375	21.351	PhosphoSitePlus	COSMIC	19.028	Down-regulation
STE_STE20_PAKA_PAK1_ST	P08670	VIM	Q13153	PAK1	S56	S55A	55	Missense	proximal	-1	no	22.375	19.824	PhosphoSitePlus	COSMIC	19.028	Down-regulation
STE_STE20_PAKA_PAK1_ST	P08670	VIM	Q13153	PAK1	S56	G59V	59	Missense	distal	3	no	22.375	21.088	PhosphoSitePlus	COSMIC	19.028	Down-regulation
STE_STE20_PAKA_PAK1_ST	P08670	VIM	Q13153	PAK1	S56	S51N	51	Missense	distal	-5	no	22.375	23.011	PhosphoSitePlus	COSMIC	19.028	Up-regulation
STE_STE20_PAKA_PAK1_ST	P08670	VIM	Q13153	PAK1	S56	S56Y	56	Missense	central	0	yes	22.375	0.000	PhosphoSitePlus	COSMIC	19.028	Loss
STE_STE20_PAKA_PAK1_ST	P08670	VIM	Q13153	PAK1	S66	R64H	64	Missense	proximal	-2	no	25.465	20.051	EPSD	COSMIC	19.028	Down-regulation
STE_STE20_PAKA_PAK1_ST	P08670	VIM	Q13153	PAK1	S66	G59N	59	Missense	distal	-7	no	25.465	25.736	EPSD	COSMIC	19.028	Up-regulation
STE_STE20_PAKA_PAK1_ST	P08670	VIM	Q13153	PAK1	S66	G59V	59	Missense	distal	-7	no	25.465	24.797	EPSD	COSMIC	19.028	Down-regulation
STE_STE20_PAKA_PAK1_ST	P08670	VIM	Q13153	PAK1	S66	R71Q	71	Missense	distal	5	no	25.465	25.462	EPSD	COSMIC	19.028	Down-regulation
STE_STE20_PAKA_PAK1_ST	P08670	VIM	Q13153	PAK1	S66	S65F	65	Missense	proximal	-1	no	25.465	26.262	EPSD	COSMIC	19.028	Up-regulation
STE_STE20_PAKA_PAK1_ST	P08670	VIM	Q13153	PAK1	S66	R69C	69	Missense	distal	3	no	25.465	26.461	EPSD	COSMIC	19.028	Up-regulation
STE_STE20_PAKA_PAK1_ST	P08670	VIM	Q13153	PAK1	S72	R71Q	71	Missense	proximal	-1	no	22.107	20.388	EPSD	COSMIC	19.028	Down-regulation
STE_STE20_PAKA_PAK1_ST	P08670	VIM	Q13153	PAK1	S72	S65F	65	Missense	distal	-7	no	22.107	21.109	EPSD	COSMIC	19.028	Down-regulation
STE_STE20_PAKA_PAK1_ST	P08670	VIM	Q13153	PAK1	S72	V77L	77	Missense	distal	5	no	22.107	22.105	EPSD	COSMIC	19.028	Down-regulation
STE_STE20_PAKA_PAK1_ST	P08670	VIM	Q13153	PAK1	S72	R69C	69	Missense	distal	-3	no	22.107	2.151	EPSD	COSMIC	19.028	Loss
STE_STE20_PAKA_PAK1_ST	P08670	VIM	Q13153	PAK1	S73	R71Q	71	Missense	proximal	-2	no	30.109	20.902	EPSD	COSMIC	19.028	Down-regulation
STE_STE20_PAKA_PAK1_ST	P08670	VIM	Q13153	PAK1	S73	V77L	77	Missense	distal	4	no	30.109	29.283	EPSD	COSMIC	19.028	Down-regulation
STE_STE20_PAKA_PAK1_ST	P08670	VIM	Q13153	PAK1	S73	R69C	69	Missense	distal	-4	no	30.109	29.149	EPSD	COSMIC	19.028	Down-regulation
STE_STE20_PAKA_PAK1_ST	P08670	VIM	Q13153	PAK1	T426	E425K	425	Missense	proximal	-1	no	18.484	20.965	EPSD	COSMIC	19.028	Gain
Atypical_Alpha_ChaK_TRPM6_ST	Q9BX84	TRPM6	Q9BX84	TRPM6	T696	W702C	702	Missense	distal	6	no	1.751	1.793	EPSD	COSMIC	1.085	Up-regulation
Atypical_Alpha_ChaK_TRPM6_ST	Q9BX84	TRPM6	Q9BX84	TRPM6	S1560	N1558I	1558	Missense	proximal	-2	no	1.569	1.678	EPSD	COSMIC	1.085	Up-regulation
Atypical_Alpha_ChaK_TRPM6_ST	Q9BX84	TRPM6	Q9BX84	TRPM6	S1560	G1561D	1561	Missense	proximal	1	no	1.569	1.519	EPSD	COSMIC	1.085	Down-regulation
Atypical_Alpha_ChaK_TRPM6_ST	Q9BX84	TRPM6	Q9BX84	TRPM6	S1560	L1559F	1559	Missense	proximal	-1	no	1.569	1.643	EPSD	COSMIC	1.085	Up-regulation
Atypical_Alpha_ChaK_TRPM6_ST	Q9BX84	TRPM6	Q9BX84	TRPM6	S1699	S1702I	1702	Missense	distal	3	no	0.999	1.174	EPSD	COSMIC	1.085	Gain
Atypical_Alpha_ChaK_TRPM6_ST	Q9BX84	TRPM6	Q9BX84	TRPM6	T1851	V1847E	1847	Missense	distal	-4	no	5.933	5.875	PhosphoSitePlus	COSMIC	1.085	Down-regulation
Atypical_Alpha_ChaK_TRPM6_ST	Q9BX84	TRPM6	Q9BX84	TRPM6	T1851	T1851N	1851	Missense	central	0	yes	5.933	0.000	PhosphoSitePlus	COSMIC	1.085	Loss
Atypical_Alpha_ChaK_TRPM6_ST	Q9BX84	TRPM6	Q9BX84	TRPM6	T1851	R1857M	1857	Missense	distal	6	no	5.933	5.902	PhosphoSitePlus	COSMIC	1.085	Down-regulation
Other_WNK_WNK1_ST	O94913	PCF11	Q9H4A3	WNK1	T327	T327I	327	Missense	central	0	yes	0.000	0.000	EPSD	COSMIC	0.000	Loss
Other_WNK_WNK1_ST	O94913	PCF11	Q9H4A3	WNK1	T561	T561I	561	Missense	central	0	yes	0.000	0.000	EPSD	COSMIC;GDSC;CCLE	0.000	Loss
Other_WNK_WNK1_ST	O94913	PCF11	Q9H4A3	WNK1	S963	E957Q	957	Missense	distal	-6	no	0.000	-0.001	EPSD	COSMIC	0.000	Loss
Other_WNK_WNK1_ST	O94913	PCF11	Q9H4A3	WNK1	T1114	T1114K	1114	Missense	central	0	yes	0.000	0.000	EPSD	COSMIC	0.000	Loss
Other_WNK_WNK1_ST	O94913	PCF11	Q9H4A3	WNK1	S1274	S1274L	1274	Missense	central	0	yes	0.000	0.000	EPSD	COSMIC	0.000	Loss
Other_WNK_WNK1_ST	O94913	PCF11	Q9H4A3	WNK1	S1495	S1495G	1495	Missense	central	0	yes	0.000	0.000	EPSD	COSMIC	0.000	Loss
Other_WNK_WNK1_ST	O94913	PCF11	Q9H4A3	WNK1	S1520	S1520G	1520	Missense	central	0	yes	0.000	0.000	EPSD	COSMIC	0.000	Loss
Other_WNK_WNK1_ST	O95747	OXSR1	Q9H4A3	WNK1	T178	T178A	178	Missense	central	0	yes	0.000	0.000	EPSD	COSMIC	0.000	Loss
Other_WNK_WNK1_ST	O95747	OXSR1	Q9H4A3	WNK1	T185	T189P	189	Missense	distal	4	no	0.002	0.001	EPSD;PhosphoSitePlus	COSMIC	0.000	Down-regulation
Other_WNK_WNK1_ST	O95747	OXSR1	Q9H4A3	WNK1	T189	T189P	189	Missense	central	0	yes	0.000	0.000	EPSD	COSMIC	0.000	Loss
Other_WNK_WNK1_ST	Q9H4A3	WNK1	Q9H4A3	WNK1	T51	R58Q	58	Missense	distal	7	no	0.001	0.000	EPSD	COSMIC	0.000	Down-regulation
Other_WNK_WNK1_ST	Q9H4A3	WNK1	Q9H4A3	WNK1	S167	S167F	167	Missense	central	0	yes	0.000	0.000	EPSD	COSMIC	0.000	Loss
Other_WNK_WNK1_ST	Q9H4A3	WNK1	Q9H4A3	WNK1	S378	A372P	372	Missense	distal	-6	no	0.001	0.000	EPSD	COSMIC	0.000	Down-regulation
Other_WNK_WNK1_ST	Q9H4A3	WNK1	Q9H4A3	WNK1	S378	S378P	378	Missense	central	0	yes	0.001	0.000	EPSD	COSMIC	0.000	Loss
Other_WNK_WNK1_ST	Q9H4A3	WNK1	Q9H4A3	WNK1	S437	S437R	437	Missense	central	0	yes	0.000	0.000	EPSD	COSMIC	0.000	Loss
Other_WNK_WNK1_ST	Q9H4A3	WNK1	Q9H4A3	WNK1	S443	S437R	437	Missense	distal	-6	no	0.000	0.001	EPSD	COSMIC	0.000	Up-regulation
Other_WNK_WNK1_ST	Q9H4A3	WNK1	Q9H4A3	WNK1	S676	T674A	674	Missense	proximal	-2	no	-0.001	0.000	EPSD	COSMIC	0.000	Gain
Other_WNK_WNK1_ST	Q9H4A3	WNK1	Q9H4A3	WNK1	T1098	T1098I	1098	Missense	central	0	yes	0.001	0.000	EPSD	COSMIC	0.000	Loss
Other_WNK_WNK1_ST	Q9H4A3	WNK1	Q9H4A3	WNK1	S1110	S1110C	1110	Missense	central	0	yes	0.001	0.000	EPSD	COSMIC	0.000	Loss
Other_WNK_WNK1_ST	Q9H4A3	WNK1	Q9H4A3	WNK1	S1193	S1193N	1193	Missense	central	0	yes	0.000	0.000	EPSD	COSMIC	0.000	Loss
Other_WNK_WNK1_ST	Q9H4A3	WNK1	Q9H4A3	WNK1	S1197	S1197N	1197	Missense	central	0	yes	0.000	0.000	EPSD	COSMIC	0.000	Loss
Other_WNK_WNK1_ST	Q9H4A3	WNK1	Q9H4A3	WNK1	S1208	S1208P	1208	Missense	central	0	yes	0.000	0.000	EPSD	COSMIC	0.000	Loss
Other_WNK_WNK1_ST	Q9H4A3	WNK1	Q9H4A3	WNK1	S1246	S1246C	1246	Missense	central	0	yes	0.000	0.000	EPSD	COSMIC	0.000	Loss
Other_WNK_WNK1_ST	Q9H4A3	WNK1	Q9H4A3	WNK1	S1297	S1297C	1297	Missense	central	0	yes	0.000	0.000	EPSD	COSMIC	0.000	Loss
Other_WNK_WNK1_ST	Q9H4A3	WNK1	Q9H4A3	WNK1	S1302	S1302A	1302	Missense	central	0	yes	0.000	0.000	EPSD	COSMIC	0.000	Loss
Other_WNK_WNK1_ST	Q9H4A3	WNK1	Q9H4A3	WNK1	S1302	S1302F	1302	Missense	central	0	yes	0.000	0.000	EPSD	COSMIC	0.000	Loss
Other_WNK_WNK1_ST	Q9H4A3	WNK1	Q9H4A3	WNK1	S1528	S1535N	1535	Missense	distal	7	no	-0.001	0.000	EPSD	COSMIC;GDSC;CCLE	0.000	Gain
Other_WNK_WNK1_ST	Q9H4A3	WNK1	Q9H4A3	WNK1	S1528	V1522M	1522	Missense	distal	-6	no	-0.001	0.000	EPSD	COSMIC	0.000	Gain
Other_WNK_WNK1_ST	Q9H4A3	WNK1	Q9H4A3	WNK1	S1819	S1819L	1819	Missense	central	0	yes	0.000	0.000	EPSD	COSMIC	0.000	Loss
Other_WNK_WNK1_ST	Q9H4A3	WNK1	Q9H4A3	WNK1	S1849	S1849N	1849	Missense	central	0	yes	0.000	0.000	EPSD	COSMIC	0.000	Loss
Other_WNK_WNK1_ST	Q9H4A3	WNK1	Q9H4A3	WNK1	S1887	S1887C	1887	Missense	central	0	yes	0.000	0.000	EPSD	COSMIC	0.000	Loss
Other_WNK_WNK1_ST	Q9H4A3	WNK1	Q9H4A3	WNK1	S1892	S1892F	1892	Missense	central	0	yes	0.000	0.000	EPSD	COSMIC	0.000	Loss
Other_WNK_WNK1_ST	Q9H4A3	WNK1	Q9H4A3	WNK1	S1897	S1897N	1897	Missense	central	0	yes	0.000	0.000	EPSD	COSMIC	0.000	Loss
Other_WNK_WNK1_ST	Q9H4A3	WNK1	Q9H4A3	WNK1	S1898	S1898I	1898	Missense	central	0	yes	0.000	0.000	EPSD	COSMIC	0.000	Loss
Other_WNK_WNK1_ST	Q9H4A3	WNK1	Q9H4A3	WNK1	S2005	P2004R	2004	Missense	proximal	-1	no	-0.001	0.000	EPSD	COSMIC	0.000	Gain
Other_WNK_WNK1_ST	Q9H4A3	WNK1	Q9H4A3	WNK1	S2020	P2014S	2014	Missense	distal	-6	no	-0.001	0.000	EPSD	COSMIC	0.000	Gain
Other_WNK_WNK1_ST	Q9H4A3	WNK1	Q9H4A3	WNK1	S2027	S2027N	2027	Missense	central	0	yes	0.000	0.000	EPSD	COSMIC	0.000	Loss
Other_WNK_WNK1_ST	Q9H4A3	WNK1	Q9H4A3	WNK1	S2121	P2119R	2119	Missense	proximal	-2	no	-0.001	0.000	EPSD	COSMIC	0.000	Gain
Other_WNK_WNK1_ST	Q9H4A3	WNK1	Q9H4A3	WNK1	S2191	S2191G	2191	Missense	central	0	yes	0.000	0.000	EPSD	COSMIC;GDSC;CCLE	0.000	Loss
Other_WNK_WNK1_ST	Q9H4A3	WNK1	Q9H4A3	WNK1	T2296	T2296A	2296	Missense	central	0	yes	0.000	0.000	EPSD	COSMIC	0.000	Loss
Other_WNK_WNK1_ST	Q9H4A3	WNK1	Q9H4A3	WNK1	S2306	S2306F	2306	Missense	central	0	yes	0.000	0.000	EPSD	COSMIC	0.000	Loss
Other_WNK_WNK1_ST	Q9UHW9	SLC12A6	Q9H4A3	WNK1	S29	S29P	29	Missense	central	0	yes	0.000	0.000	EPSD	COSMIC;CCLE	0.000	Loss
Other_WNK_WNK1_ST	Q9UHW9	SLC12A6	Q9H4A3	WNK1	S32	S32C	32	Missense	central	0	yes	0.000	0.000	EPSD	COSMIC	0.000	Loss
Other_WNK_WNK1_ST	Q9UHW9	SLC12A6	Q9H4A3	WNK1	S41	S41C	41	Missense	central	0	yes	0.000	0.000	EPSD	COSMIC	0.000	Loss
Other_WNK_WNK1_ST	Q9UHW9	SLC12A6	Q9H4A3	WNK1	S64	S64F	64	Missense	central	0	yes	0.000	0.000	EPSD	COSMIC	0.000	Loss
Other_WNK_WNK1_ST	Q9UHW9	SLC12A6	Q9H4A3	WNK1	S64	S64Y	64	Missense	central	0	yes	0.000	0.000	EPSD	COSMIC	0.000	Loss
Other_WNK_WNK1_ST	Q9UHW9	SLC12A6	Q9H4A3	WNK1	S79	P78H	78	Missense	proximal	-1	no	-0.001	0.000	EPSD	COSMIC	0.000	Gain
Other_WNK_WNK1_ST	Q9UHW9	SLC12A6	Q9H4A3	WNK1	S120	N119K	119	Missense	proximal	-1	no	0.000	0.001	EPSD	COSMIC	0.000	Up-regulation
Other_WNK_WNK1_ST	Q9UHW9	SLC12A6	Q9H4A3	WNK1	S781	S781L	781	Missense	central	0	yes	0.000	0.000	EPSD	COSMIC	0.000	Loss
Other_WNK_WNK1_ST	Q9UHW9	SLC12A6	Q9H4A3	WNK1	S1007	R1011P	1011	Missense	distal	4	no	0.001	0.000	EPSD	COSMIC	0.000	Down-regulation
Other_WNK_WNK1_ST	Q9UHW9	SLC12A6	Q9H4A3	WNK1	S1007	R1005Q	1005	Missense	proximal	-2	no	0.001	0.000	EPSD	COSMIC	0.000	Down-regulation
Other_WNK_WNK1_ST	Q9UHW9	SLC12A6	Q9H4A3	WNK1	S1032	R1026Q	1026	Missense	distal	-6	no	0.001	0.000	EPSD	COSMIC	0.000	Down-regulation
Other_WNK_WNK1_ST	Q9UHW9	SLC12A6	Q9H4A3	WNK1	S1032	R1026L	1026	Missense	distal	-6	no	0.001	0.000	EPSD	COSMIC	0.000	Down-regulation
Other_WNK_WNK1_ST	Q9UHW9	SLC12A6	Q9H4A3	WNK1	S1064	S1064F	1064	Missense	central	0	yes	0.001	0.000	EPSD	COSMIC	0.000	Loss
Other_WNK_WNK1_ST	Q9UHW9	SLC12A6	Q9H4A3	WNK1	S1064	R1058W	1058	Missense	distal	-6	no	0.001	0.000	EPSD	COSMIC	0.000	Down-regulation
Other_WNK_WNK1_ST	Q9UEW8	STK39	Q9H4A3	WNK1	T32	A26V	26	Missense	distal	-6	no	0.000	-0.001	EPSD	COSMIC	0.000	Loss
Other_WNK_WNK1_ST	Q9UEW8	STK39	Q9H4A3	WNK1	T219	A218V	218	Missense	proximal	-1	no	0.000	-0.001	EPSD	COSMIC	0.000	Loss
Other_WNK_WNK1_ST	Q9UEW8	STK39	Q9H4A3	WNK1	T224	T224A	224	Missense	central	0	yes	0.000	0.000	EPSD	COSMIC	0.000	Loss
Other_WNK_WNK1_ST	Q9UEW8	STK39	Q9H4A3	WNK1	S315	S315P	315	Missense	central	0	yes	0.000	0.000	EPSD	COSMIC	0.000	Loss
TK_InsR_INSR_Y	P35568	IRS1	P06213	INSR	Y431	P435L	435	Missense	distal	4	no	13.127	12.856	EPSD	COSMIC	10.312	Down-regulation
TK_InsR_INSR_Y	P35568	IRS1	P06213	INSR	Y431	S434G	434	Missense	distal	3	no	13.127	12.712	EPSD	COSMIC	10.312	Down-regulation
TK_InsR_INSR_Y	P35568	IRS1	P06213	INSR	Y431	G424C	424	Missense	distal	-7	no	13.127	12.736	EPSD	COSMIC	10.312	Down-regulation
TK_InsR_INSR_Y	P35568	IRS1	P06213	INSR	Y431	P435F	435	Missense	distal	4	no	13.127	12.634	EPSD	COSMIC	10.312	Down-regulation
TK_InsR_INSR_Y	P35568	IRS1	P06213	INSR	Y465	E460K	460	Missense	distal	-5	no	11.422	10.668	EPSD	COSMIC	10.312	Down-regulation
TK_InsR_INSR_Y	P35568	IRS1	P06213	INSR	Y465	G458A	458	Missense	distal	-7	no	11.422	11.121	EPSD	COSMIC	10.312	Down-regulation
TK_InsR_INSR_Y	P35568	IRS1	P06213	INSR	Y465	M468I	468	Missense	distal	3	no	11.422	11.165	EPSD	COSMIC;GDSC;CCLE	10.312	Down-regulation
TK_InsR_INSR_Y	P35568	IRS1	P06213	INSR	Y465	K471N	471	Missense	distal	6	no	11.422	11.568	EPSD	COSMIC	10.312	Up-regulation
TK_InsR_INSR_Y	P35568	IRS1	P06213	INSR	Y465	G472W	472	Missense	distal	7	no	11.422	11.410	EPSD	COSMIC	10.312	Down-regulation
TK_InsR_INSR_Y	P35568	IRS1	P06213	INSR	Y465	G472E	472	Missense	distal	7	no	11.422	11.428	EPSD	COSMIC	10.312	Up-regulation
TK_InsR_INSR_Y	P35568	IRS1	P06213	INSR	Y465	G470V	470	Missense	distal	5	no	11.422	11.578	EPSD	COSMIC;GDSC;CCLE	10.312	Up-regulation
TK_InsR_INSR_Y	P35568	IRS1	P06213	INSR	Y551	M554T	554	Missense	distal	3	no	10.566	10.592	EPSD	COSMIC	10.312	Up-regulation
TK_InsR_INSR_Y	P35568	IRS1	P06213	INSR	Y551	Y558C	558	Missense	distal	7	no	10.566	10.567	EPSD	COSMIC	10.312	Up-regulation
TK_InsR_INSR_Y	P35568	IRS1	P06213	INSR	Y551	Y551C	551	Missense	central	0	yes	10.566	0.000	EPSD	COSMIC	10.312	Loss
TK_InsR_INSR_Y	P35568	IRS1	P06213	INSR	Y582	P578S	578	Missense	distal	-4	no	9.979	12.113	EPSD	COSMIC	10.312	Gain
TK_InsR_INSR_Y	P35568	IRS1	P06213	INSR	Y612	P614A	614	Missense	proximal	2	no	17.286	17.011	EPSD	COSMIC;CCLE	10.312	Down-regulation
TK_InsR_INSR_Y	P35568	IRS1	P06213	INSR	Y632	G628D	628	Missense	distal	-4	no	13.734	15.232	EPSD	COSMIC	10.312	Up-regulation
TK_InsR_INSR_Y	P35568	IRS1	P06213	INSR	Y632	R626Q	626	Missense	distal	-6	no	13.734	13.728	EPSD	COSMIC	10.312	Down-regulation
TK_InsR_INSR_Y	P35568	IRS1	P06213	INSR	Y632	G630E	630	Missense	proximal	-2	no	13.734	16.015	EPSD	COSMIC	10.312	Up-regulation
TK_InsR_INSR_Y	P35568	IRS1	P06213	INSR	Y662	G661D	661	Missense	proximal	-1	no	9.340	12.344	EPSD	COSMIC	10.312	Gain
TK_InsR_INSR_Y	P35568	IRS1	P06213	INSR	Y750	Q757K	757	Missense	distal	7	no	10.498	10.499	EPSD	COSMIC	10.312	Up-regulation
TK_InsR_INSR_Y	P35568	IRS1	P06213	INSR	Y750	P753L	753	Missense	distal	3	no	10.498	10.544	EPSD	COSMIC	10.312	Up-regulation
TK_InsR_INSR_Y	P35568	IRS1	P06213	INSR	Y941	K943Q	943	Missense	proximal	2	no	20.361	20.235	EPSD	COSMIC	10.312	Down-regulation
TK_InsR_INSR_Y	P35568	IRS1	P06213	INSR	Y941	T936I	936	Missense	distal	-5	no	20.361	19.371	EPSD	COSMIC	10.312	Down-regulation
TK_InsR_INSR_Y	P35568	IRS1	P06213	INSR	Y941	L946P	946	Missense	distal	5	no	20.361	20.139	EPSD	COSMIC	10.312	Down-regulation
TK_InsR_INSR_Y	P35568	IRS1	P06213	INSR	Y989	P983S	983	Missense	distal	-6	no	17.668	17.643	PhosphoSitePlus;EPSD	COSMIC	10.312	Down-regulation
TK_InsR_INSR_Y	P35568	IRS1	P06213	INSR	Y989	S985N	985	Missense	distal	-4	no	17.668	16.355	PhosphoSitePlus;EPSD	COSMIC	10.312	Down-regulation
TK_InsR_INSR_Y	P35568	IRS1	P06213	INSR	Y989	M992K	992	Missense	distal	3	no	17.668	17.367	PhosphoSitePlus;EPSD	COSMIC	10.312	Down-regulation
TK_InsR_INSR_Y	P35568	IRS1	P06213	INSR	Y1001	R998C	998	Missense	distal	-3	no	13.473	12.396	EPSD	COSMIC;GDSC;CCLE	10.312	Down-regulation
TK_InsR_INSR_Y	P35568	IRS1	P06213	INSR	Y1001	D1003H	1003	Missense	proximal	2	no	13.473	11.555	EPSD	COSMIC	10.312	Down-regulation
TK_InsR_INSR_Y	P35568	IRS1	P06213	INSR	Y1001	P997S	997	Missense	distal	-4	no	13.473	15.607	EPSD	COSMIC	10.312	Up-regulation
TK_InsR_INSR_Y	P35568	IRS1	P06213	INSR	Y1179	G1172D	1172	Missense	distal	-7	no	15.829	16.549	EPSD;PhosphoSitePlus	COSMIC	10.312	Up-regulation
TK_InsR_INSR_Y	P35568	IRS1	P06213	INSR	Y1179	D1181E	1181	Missense	proximal	2	no	15.829	15.485	EPSD;PhosphoSitePlus	COSMIC	10.312	Down-regulation
TK_InsR_INSR_Y	P35568	IRS1	P06213	INSR	Y1179	D1181H	1181	Missense	proximal	2	no	15.829	13.912	EPSD;PhosphoSitePlus	COSMIC;GDSC;CCLE	10.312	Down-regulation
TK_InsR_INSR_Y	P35568	IRS1	P06213	INSR	Y1229	D1225Y	1225	Missense	distal	-4	no	10.599	8.581	EPSD	COSMIC	10.312	Loss
TK_InsR_INSR_Y	P35568	IRS1	P06213	INSR	Y1229	Q1235P	1235	Missense	distal	6	no	10.599	10.422	EPSD	COSMIC	10.312	Down-regulation
TK_InsR_INSR_Y	P35568	IRS1	P06213	INSR	Y1229	A1228V	1228	Missense	proximal	-1	no	10.599	11.933	EPSD	COSMIC	10.312	Up-regulation
TK_InsR_INSR_Y	P35568	IRS1	P06213	INSR	Y1229	E1224Q	1224	Missense	distal	-5	no	10.599	10.106	EPSD	COSMIC	10.312	Loss
TK_InsR_INSR_Y	P35568	IRS1	P06213	INSR	Y1229	L1226V	1226	Missense	distal	-3	no	10.599	12.416	EPSD	COSMIC	10.312	Up-regulation
TK_InsR_INSR_Y	P53004	BLVRA	P06213	INSR	Y83	H80Y	80	Missense	distal	-3	no	16.524	16.929	EPSD	COSMIC;GDSC;CCLE	10.312	Up-regulation
TK_InsR_INSR_Y	P53004	BLVRA	P06213	INSR	Y83	H80R	80	Missense	distal	-3	no	16.524	17.490	EPSD	COSMIC;GDSC;CCLE	10.312	Up-regulation
TK_InsR_INSR_Y	P53004	BLVRA	P06213	INSR	Y198	R193Q	193	Missense	distal	-5	no	12.819	13.262	EPSD;PhosphoSitePlus	COSMIC;GDSC;CCLE	10.312	Up-regulation
TK_InsR_INSR_Y	P53004	BLVRA	P06213	INSR	Y228	R225Q	225	Missense	distal	-3	no	11.369	12.485	PhosphoSitePlus;EPSD	COSMIC	10.312	Up-regulation
TK_InsR_INSR_Y	P53004	BLVRA	P06213	INSR	Y228	S235Y	235	Missense	distal	7	no	11.369	11.358	PhosphoSitePlus;EPSD	COSMIC	10.312	Down-regulation
TK_InsR_INSR_Y	P53004	BLVRA	P06213	INSR	Y228	R227K	227	Missense	proximal	-1	no	11.369	11.900	PhosphoSitePlus;EPSD	COSMIC	10.312	Up-regulation
TK_InsR_INSR_Y	P06213	INSR	P06213	INSR	Y401	A402S	402	Missense	proximal	1	no	8.628	10.508	EPSD	COSMIC	10.312	Gain
TK_InsR_INSR_Y	P06213	INSR	P06213	INSR	Y999	A993T	993	Missense	distal	-6	no	12.712	12.701	EPSD;PhosphoSitePlus	COSMIC	10.312	Down-regulation
TK_InsR_INSR_Y	P06213	INSR	P06213	INSR	Y999	S1001I	1001	Missense	proximal	2	no	12.712	10.125	EPSD;PhosphoSitePlus	COSMIC	10.312	Loss
TK_InsR_INSR_Y	P06213	INSR	P06213	INSR	Y999	P997L	997	Missense	proximal	-2	no	12.712	10.729	EPSD;PhosphoSitePlus	COSMIC	10.312	Down-regulation
TK_InsR_INSR_Y	P06213	INSR	P06213	INSR	Y999	S995A	995	Missense	distal	-4	no	12.712	10.567	EPSD;PhosphoSitePlus	COSMIC	10.312	Down-regulation
TK_InsR_INSR_Y	P06213	INSR	P06213	INSR	Y999	D1004G	1004	Missense	distal	5	no	12.712	13.115	EPSD;PhosphoSitePlus	COSMIC	10.312	Up-regulation
TK_InsR_INSR_Y	P06213	INSR	P06213	INSR	Y1011	V1012L	1012	Missense	proximal	1	no	10.498	8.525	EPSD;PhosphoSitePlus	COSMIC;GDSC	10.312	Loss
TK_InsR_INSR_Y	P06213	INSR	P06213	INSR	Y1011	E1017K	1017	Missense	distal	6	no	10.498	10.301	EPSD;PhosphoSitePlus	COSMIC	10.312	Loss
TK_InsR_INSR_Y	P06213	INSR	P06213	INSR	Y1011	D1004G	1004	Missense	distal	-7	no	10.498	9.778	EPSD;PhosphoSitePlus	COSMIC	10.312	Loss
TK_InsR_INSR_Y	P06213	INSR	P06213	INSR	Y1185	Y1190C	1190	Missense	distal	5	no	13.813	13.803	EPSD;PhosphoSitePlus	COSMIC	10.312	Down-regulation
TK_InsR_INSR_Y	P06213	INSR	P06213	INSR	Y1185	R1191W	1191	Missense	distal	6	no	13.813	13.381	EPSD;PhosphoSitePlus	COSMIC	10.312	Down-regulation
TK_InsR_INSR_Y	P06213	INSR	P06213	INSR	Y1185	G1179R	1179	Missense	distal	-6	no	13.813	13.814	EPSD;PhosphoSitePlus	COSMIC	10.312	Up-regulation
TK_InsR_INSR_Y	P06213	INSR	P06213	INSR	Y1189	Y1190C	1190	Missense	proximal	1	no	14.032	14.004	EPSD;PhosphoSitePlus	COSMIC	10.312	Down-regulation
TK_InsR_INSR_Y	P06213	INSR	P06213	INSR	Y1189	R1191W	1191	Missense	proximal	2	no	14.032	12.047	EPSD;PhosphoSitePlus	COSMIC	10.312	Down-regulation
TK_InsR_INSR_Y	P06213	INSR	P06213	INSR	Y1190	Y1190C	1190	Missense	central	0	yes	14.970	0.000	EPSD;PhosphoSitePlus	COSMIC	10.312	Loss
TK_InsR_INSR_Y	P06213	INSR	P06213	INSR	Y1190	R1191W	1191	Missense	proximal	1	no	14.970	12.581	EPSD;PhosphoSitePlus	COSMIC	10.312	Down-regulation
TK_InsR_INSR_Y	P06213	INSR	P06213	INSR	Y1355	R1353W	1353	Missense	proximal	-2	no	11.720	7.113	EPSD;PhosphoSitePlus	COSMIC	10.312	Loss
TK_InsR_INSR_Y	P06213	INSR	P06213	INSR	Y1355	P1360S	1360	Missense	distal	5	no	11.720	10.790	EPSD;PhosphoSitePlus	COSMIC	10.312	Down-regulation
TK_InsR_INSR_Y	P06213	INSR	P06213	INSR	Y1361	P1360S	1360	Missense	proximal	-1	no	9.985	12.784	EPSD;PhosphoSitePlus	COSMIC	10.312	Gain
TK_InsR_INSR_Y	P27986	PIK3R1	P06213	INSR	Y504	R503W	503	Missense	proximal	-1	no	14.060	10.481	EPSD	COSMIC	10.312	Down-regulation
TK_InsR_INSR_Y	P27986	PIK3R1	P06213	INSR	Y504	E507G	507	Missense	distal	3	no	14.060	13.970	EPSD	COSMIC	10.312	Down-regulation
TK_InsR_INSR_Y	P27986	PIK3R1	P06213	INSR	Y504	E510K	510	Missense	distal	6	no	14.060	13.863	EPSD	COSMIC	10.312	Down-regulation
TK_InsR_INSR_Y	P27986	PIK3R1	P06213	INSR	Y504	R503Q	503	Missense	proximal	-1	no	14.060	15.651	EPSD	COSMIC	10.312	Up-regulation
TK_InsR_INSR_Y	P27986	PIK3R1	P06213	INSR	Y607	Q606H	606	Missense	proximal	-1	no	17.471	14.873	PhosphoSitePlus;EPSD	COSMIC	10.312	Down-regulation
TK_InsR_INSR_Y	P27986	PIK3R1	P06213	INSR	Y607	E614K	614	Missense	distal	7	no	17.471	17.468	PhosphoSitePlus;EPSD	COSMIC	10.312	Down-regulation
TK_InsR_INSR_Y	P27986	PIK3R1	P06213	INSR	Y607	E611K	611	Missense	distal	4	no	17.471	16.971	PhosphoSitePlus;EPSD	COSMIC	10.312	Down-regulation
TK_InsR_INSR_Y	P27986	PIK3R1	P06213	INSR	Y607	E601K	601	Missense	distal	-6	no	17.471	17.477	PhosphoSitePlus;EPSD	COSMIC	10.312	Up-regulation
TK_InsR_INSR_Y	Q13480	GAB1	P06213	INSR	Y285	T289I	289	Missense	distal	4	no	13.084	12.469	EPSD;PhosphoSitePlus	COSMIC	10.312	Down-regulation
TK_InsR_INSR_Y	Q13480	GAB1	P06213	INSR	Y373	A378S	378	Missense	distal	5	no	11.973	11.306	EPSD;PhosphoSitePlus	COSMIC	10.312	Down-regulation
TK_InsR_INSR_Y	Q13480	GAB1	P06213	INSR	Y373	A366V	366	Missense	distal	-7	no	11.973	12.138	EPSD;PhosphoSitePlus	COSMIC	10.312	Up-regulation
TK_InsR_INSR_Y	Q13480	GAB1	P06213	INSR	Y406	P413L	413	Missense	distal	7	no	10.487	10.485	EPSD	COSMIC	10.312	Down-regulation
TK_InsR_INSR_Y	Q13480	GAB1	P06213	INSR	Y447	P449H	449	Missense	proximal	2	no	17.503	17.106	EPSD;PhosphoSitePlus	COSMIC	10.312	Down-regulation
TK_InsR_INSR_Y	Q13480	GAB1	P06213	INSR	Y447	E441Q	441	Missense	distal	-6	no	17.503	17.505	EPSD;PhosphoSitePlus	COSMIC	10.312	Up-regulation
TK_InsR_INSR_Y	Q13480	GAB1	P06213	INSR	Y589	L596M	596	Missense	distal	7	no	18.236	18.241	EPSD;PhosphoSitePlus	COSMIC	10.312	Up-regulation
TK_InsR_INSR_Y	Q13480	GAB1	P06213	INSR	Y589	N595D	595	Missense	distal	6	no	18.236	18.292	EPSD;PhosphoSitePlus	COSMIC	10.312	Up-regulation
TK_InsR_INSR_Y	Q13480	GAB1	P06213	INSR	Y589	P591H	591	Missense	proximal	2	no	18.236	17.839	EPSD;PhosphoSitePlus	COSMIC	10.312	Down-regulation
TK_InsR_INSR_Y	Q13480	GAB1	P06213	INSR	Y589	N593S	593	Missense	distal	4	no	18.236	18.571	EPSD;PhosphoSitePlus	COSMIC	10.312	Up-regulation
TK_InsR_INSR_Y	Q13480	GAB1	P06213	INSR	Y589	S585R	585	Missense	distal	-4	no	18.236	16.613	EPSD;PhosphoSitePlus	COSMIC	10.312	Down-regulation
TK_InsR_INSR_Y	Q13480	GAB1	P06213	INSR	Y589	N588K	588	Missense	proximal	-1	no	18.236	16.424	EPSD;PhosphoSitePlus	COSMIC	10.312	Down-regulation
TK_InsR_INSR_Y	Q13480	GAB1	P06213	INSR	Y627	D631F	631	Missense	distal	4	no	13.168	11.605	EPSD;PhosphoSitePlus	COSMIC	10.312	Down-regulation
TK_InsR_INSR_Y	Q13480	GAB1	P06213	INSR	Y627	D631Y	631	Missense	distal	4	no	13.168	12.178	EPSD;PhosphoSitePlus	COSMIC	10.312	Down-regulation
TK_InsR_INSR_Y	Q13480	GAB1	P06213	INSR	Y627	D631V	631	Missense	distal	4	no	13.168	12.289	EPSD;PhosphoSitePlus	COSMIC	10.312	Down-regulation
TK_InsR_INSR_Y	Q13480	GAB1	P06213	INSR	Y627	Q624L	624	Missense	distal	-3	no	13.168	9.783	EPSD;PhosphoSitePlus	COSMIC	10.312	Loss
TK_InsR_INSR_Y	Q13480	GAB1	P06213	INSR	Y627	L632I	632	Missense	distal	5	no	13.168	13.131	EPSD;PhosphoSitePlus	COSMIC	10.312	Down-regulation
TK_InsR_INSR_Y	Q13480	GAB1	P06213	INSR	Y627	D631N	631	Missense	distal	4	no	13.168	12.642	EPSD;PhosphoSitePlus	COSMIC	10.312	Down-regulation
TK_InsR_INSR_Y	Q13017	ARHGAP5	P06213	INSR	Y306	H300R	300	Missense	distal	-6	no	13.779	13.772	PhosphoSitePlus	COSMIC	10.312	Down-regulation
TK_InsR_INSR_Y	Q13017	ARHGAP5	P06213	INSR	Y306	P301L	301	Missense	distal	-5	no	13.779	13.162	PhosphoSitePlus	COSMIC;GDSC;CCLE	10.312	Down-regulation
TK_InsR_INSR_Y	Q13017	ARHGAP5	P06213	INSR	Y306	G311R	311	Missense	distal	5	no	13.779	13.582	PhosphoSitePlus	COSMIC	10.312	Down-regulation
TK_InsR_INSR_Y	Q13017	ARHGAP5	P06213	INSR	Y978	P974S	974	Missense	distal	-4	no	9.192	11.326	EPSD	COSMIC	10.312	Gain
TK_InsR_INSR_Y	Q13017	ARHGAP5	P06213	INSR	Y1091	D1084Y	1084	Missense	distal	-7	no	17.232	16.195	EPSD	COSMIC	10.312	Down-regulation
TK_InsR_INSR_Y	Q99704	DOK1	P06213	INSR	Y146	E142Q	142	Missense	distal	-4	no	10.363	9.690	EPSD	COSMIC	10.312	Loss
TK_InsR_INSR_Y	Q99704	DOK1	P06213	INSR	Y315	D320N	320	Missense	distal	5	no	14.208	14.224	EPSD	COSMIC	10.312	Up-regulation
TK_InsR_INSR_Y	Q99704	DOK1	P06213	INSR	Y362	G367C	367	Missense	distal	5	no	14.400	14.514	EPSD;PhosphoSitePlus	COSMIC	10.312	Up-regulation
TK_InsR_INSR_Y	Q99704	DOK1	P06213	INSR	Y398	V393L	393	Missense	distal	-5	no	11.865	11.108	PhosphoSitePlus;EPSD	COSMIC	10.312	Down-regulation
TK_InsR_INSR_Y	P60484	PTEN	P06213	INSR	Y27	L23V	23	Missense	distal	-4	no	9.201	10.350	EPSD;PhosphoSitePlus	COSMIC	10.312	Gain
TK_InsR_INSR_Y	P60484	PTEN	P06213	INSR	Y27	L25S	25	Missense	proximal	-2	no	9.201	14.507	EPSD;PhosphoSitePlus	COSMIC	10.312	Gain
TK_InsR_INSR_Y	P60484	PTEN	P06213	INSR	Y27	I28M	28	Missense	proximal	1	no	9.201	10.336	EPSD;PhosphoSitePlus	COSMIC	10.312	Gain
TK_InsR_INSR_Y	P60484	PTEN	P06213	INSR	Y27	L23S	23	Missense	distal	-4	no	9.201	12.150	EPSD;PhosphoSitePlus	COSMIC	10.312	Gain
TK_InsR_INSR_Y	P60484	PTEN	P06213	INSR	Y155	F154S	154	Missense	proximal	-1	no	5.946	10.776	EPSD	COSMIC	10.312	Gain
TK_InsR_INSR_Y	P60484	PTEN	P06213	INSR	Y174	P169S	169	Missense	distal	-5	no	9.762	11.002	PhosphoSitePlus;EPSD	COSMIC	10.312	Gain
TK_InsR_INSR_Y	P60484	PTEN	P06213	INSR	Y174	S179I	179	Missense	distal	5	no	9.762	10.877	PhosphoSitePlus;EPSD	COSMIC	10.312	Gain
TK_InsR_INSR_Y	P60484	PTEN	P06213	INSR	Y174	Y178D	178	Missense	distal	4	no	9.762	10.751	PhosphoSitePlus;EPSD	COSMIC	10.312	Gain
TK_InsR_INSR_Y	P60484	PTEN	P06213	INSR	Y174	R173S	173	Missense	proximal	-1	no	9.762	12.101	PhosphoSitePlus;EPSD	COSMIC	10.312	Gain
TK_InsR_INSR_Y	P60484	PTEN	P06213	INSR	Y315	L318F	318	Missense	distal	3	no	12.360	12.130	EPSD	COSMIC	10.312	Down-regulation
TK_InsR_INSR_Y	P60484	PTEN	P06213	INSR	Y315	L320V	320	Missense	distal	5	no	12.360	12.035	EPSD	COSMIC	10.312	Down-regulation
TK_InsR_INSR_Y	P60484	PTEN	P06213	INSR	Y315	Y315H	315	Missense	central	0	yes	12.360	0.000	EPSD	COSMIC	10.312	Loss
TK_InsR_INSR_Y	P60484	PTEN	P06213	INSR	Y315	L318P	318	Missense	distal	3	no	12.360	12.314	EPSD	COSMIC	10.312	Down-regulation
TK_InsR_INSR_Y	P60484	PTEN	P06213	INSR	Y315	R308H	308	Missense	distal	-7	no	12.360	12.033	EPSD	COSMIC	10.312	Down-regulation
TK_InsR_INSR_Y	P60484	PTEN	P06213	INSR	Y315	V317G	317	Missense	proximal	2	no	12.360	12.732	EPSD	COSMIC	10.312	Up-regulation
TK_InsR_INSR_Y	P60484	PTEN	P06213	INSR	Y315	E314K	314	Missense	proximal	-1	no	12.360	10.118	EPSD	COSMIC	10.312	Loss
TK_InsR_INSR_Y	P60484	PTEN	P06213	INSR	Y315	T321I	321	Missense	distal	6	no	12.360	12.164	EPSD	COSMIC	10.312	Down-regulation
TK_InsR_INSR_Y	P60484	PTEN	P06213	INSR	Y377	D375N	375	Missense	proximal	-2	no	12.774	10.635	EPSD	COSMIC	10.312	Down-regulation
TK_InsR_INSR_Y	P60484	PTEN	P06213	INSR	Y377	T383I	383	Missense	distal	6	no	12.774	12.578	EPSD	COSMIC	10.312	Down-regulation
TK_InsR_INSR_Y	P60484	PTEN	P06213	INSR	Y377	D384N	384	Missense	distal	7	no	12.774	12.775	EPSD	COSMIC	10.312	Up-regulation
TK_InsR_INSR_Y	P60484	PTEN	P06213	INSR	Y377	T382S	382	Missense	distal	5	no	12.774	12.396	EPSD	COSMIC	10.312	Down-regulation
TK_InsR_INSR_Y	P60484	PTEN	P06213	INSR	Y377	D384G	384	Missense	distal	7	no	12.774	12.772	EPSD	COSMIC	10.312	Down-regulation
TK_InsR_INSR_Y	P60484	PTEN	P06213	INSR	Y379	D375N	375	Missense	distal	-4	no	12.398	11.218	EPSD	COSMIC	10.312	Down-regulation
TK_InsR_INSR_Y	P60484	PTEN	P06213	INSR	Y379	T383I	383	Missense	distal	4	no	12.398	11.783	EPSD	COSMIC	10.312	Down-regulation
TK_InsR_INSR_Y	P60484	PTEN	P06213	INSR	Y379	D384N	384	Missense	distal	5	no	12.398	12.414	EPSD	COSMIC	10.312	Up-regulation
TK_InsR_INSR_Y	P60484	PTEN	P06213	INSR	Y379	T382S	382	Missense	distal	3	no	12.398	12.578	EPSD	COSMIC	10.312	Up-regulation
TK_InsR_INSR_Y	P60484	PTEN	P06213	INSR	Y379	D384G	384	Missense	distal	5	no	12.398	12.800	EPSD	COSMIC	10.312	Up-regulation
TK_InsR_INSR_Y	Q92569	PIK3R3	P06213	INSR	Y341	Y341F	341	Missense	central	0	yes	15.740	0.000	PhosphoSitePlus	COSMIC	10.312	Loss
TK_InsR_INSR_Y	Q92569	PIK3R3	P06213	INSR	Y341	E345K	345	Missense	distal	4	no	15.740	15.240	PhosphoSitePlus	COSMIC	10.312	Down-regulation
TK_InsR_INSR_Y	Q92569	PIK3R3	P06213	INSR	Y341	E348K	348	Missense	distal	7	no	15.740	15.737	PhosphoSitePlus	COSMIC	10.312	Down-regulation
TK_InsR_INSR_Y	Q92569	PIK3R3	P06213	INSR	Y341	I343F	343	Missense	proximal	2	no	15.740	15.234	PhosphoSitePlus	COSMIC	10.312	Down-regulation
TK_InsR_INSR_Y	Q92569	PIK3R3	P06213	INSR	Y422	Y419S	419	Missense	distal	-3	no	8.638	11.173	EPSD	COSMIC	10.312	Gain
TK_InsR_INSR_Y	P29350	PTPN6	P06213	INSR	Y176	T183S	183	Missense	distal	7	no	10.367	10.371	EPSD	COSMIC	10.312	Up-regulation
TK_InsR_INSR_Y	P29350	PTPN6	P06213	INSR	Y176	V178A	178	Missense	proximal	2	no	10.367	10.088	EPSD	COSMIC	10.312	Loss
TK_InsR_INSR_Y	P29350	PTPN6	P06213	INSR	Y176	R175H	175	Missense	proximal	-1	no	10.367	9.361	EPSD	COSMIC	10.312	Loss
TK_InsR_INSR_Y	P29350	PTPN6	P06213	INSR	Y176	Y176N	176	Missense	central	0	yes	10.367	0.000	EPSD	COSMIC	10.312	Loss
TK_InsR_INSR_Y	P29350	PTPN6	P06213	INSR	Y301	I302N	302	Missense	proximal	1	no	10.582	10.904	EPSD	COSMIC	10.312	Up-regulation
TK_InsR_INSR_Y	P29350	PTPN6	P06213	INSR	Y301	P297H	297	Missense	distal	-4	no	10.582	10.212	EPSD	COSMIC	10.312	Loss
TK_InsR_INSR_Y	P29350	PTPN6	P06213	INSR	Y301	G298V	298	Missense	distal	-3	no	10.582	9.565	EPSD	COSMIC	10.312	Loss
TK_InsR_INSR_Y	P29350	PTPN6	P06213	INSR	Y536	E535G	535	Missense	proximal	-1	no	17.447	16.085	PhosphoSitePlus	COSMIC	10.312	Down-regulation
TK_InsR_INSR_Y	P29350	PTPN6	P06213	INSR	Y536	G537R	537	Missense	proximal	1	no	17.447	16.962	PhosphoSitePlus	COSMIC	10.312	Down-regulation
TK_InsR_INSR_Y	P29350	PTPN6	P06213	INSR	Y564	N571Y	571	Missense	distal	7	no	12.156	12.152	EPSD	COSMIC	10.312	Down-regulation
TK_InsR_INSR_Y	P35232	PHB	P06213	INSR	Y114	E112D	112	Missense	proximal	-2	no	16.235	17.526	PhosphoSitePlus	COSMIC	10.312	Up-regulation
TK_InsR_INSR_Y	P35232	PHB	P06213	INSR	Y114	F107L	107	Missense	distal	-7	no	16.235	16.389	PhosphoSitePlus	COSMIC	10.312	Up-regulation
TK_InsR_INSR_Y	P35232	PHB	P06213	INSR	Y114	D115N	115	Missense	proximal	1	no	16.235	14.910	PhosphoSitePlus	COSMIC;GDSC;CCLE	10.312	Down-regulation
TK_InsR_INSR_Y	Q9P219	CCDC88C	P06213	INSR	Y1699	R1692W	1692	Missense	distal	-7	no	11.100	9.851	EPSD	COSMIC	10.312	Loss
TK_InsR_INSR_Y	P25963	NFKBIA	P06213	INSR	Y42	M37K	37	Missense	distal	-5	no	14.355	14.611	PhosphoSitePlus	COSMIC	10.312	Up-regulation
TK_InsR_INSR_Y	P25963	NFKBIA	P06213	INSR	Y42	E40D	40	Missense	proximal	-2	no	14.355	15.646	PhosphoSitePlus	COSMIC	10.312	Up-regulation
TK_InsR_INSR_Y	P25963	NFKBIA	P06213	INSR	Y42	M45L	45	Missense	distal	3	no	14.355	13.845	PhosphoSitePlus	COSMIC	10.312	Down-regulation
TK_InsR_INSR_Y	P25963	NFKBIA	P06213	INSR	Y42	E43K	43	Missense	proximal	1	no	14.355	12.687	PhosphoSitePlus	COSMIC	10.312	Down-regulation
TK_InsR_INSR_Y	P25963	NFKBIA	P06213	INSR	Y42	S36P	36	Missense	distal	-6	no	14.355	14.380	PhosphoSitePlus	COSMIC	10.312	Up-regulation
TK_InsR_INSR_Y	P25963	NFKBIA	P06213	INSR	Y42	E43Q	43	Missense	proximal	1	no	14.355	13.243	PhosphoSitePlus	COSMIC	10.312	Down-regulation
TK_InsR_INSR_Y	P25963	NFKBIA	P06213	INSR	Y305	E302K	302	Missense	distal	-3	no	12.150	10.520	EPSD	COSMIC	10.312	Down-regulation
TK_InsR_INSR_Y	P25963	NFKBIA	P06213	INSR	Y305	D307E	307	Missense	proximal	2	no	12.150	11.806	EPSD	COSMIC;GDSC;CCLE	10.312	Down-regulation
TK_InsR_INSR_Y	P25963	NFKBIA	P06213	INSR	Y305	C308S	308	Missense	distal	3	no	12.150	12.731	EPSD	COSMIC	10.312	Up-regulation
TK_InsR_INSR_Y	P67775	PPP2CA	P06213	INSR	Y307	F308S	308	Missense	proximal	1	no	7.587	10.581	PhosphoSitePlus	COSMIC	10.312	Gain
STE_STE-Unique_MAP3K8_ST	P35241	RDX	P41279	MAP3K8	S249	I245V	245	Missense	distal	-4	no	22.416	22.276	EPSD	COSMIC	13.250	Down-regulation
STE_STE-Unique_MAP3K8_ST	P35241	RDX	P41279	MAP3K8	T518	R514C	514	Missense	distal	-4	no	19.290	19.670	EPSD	COSMIC;GDSC;CCLE	13.250	Up-regulation
STE_STE-Unique_MAP3K8_ST	P35241	RDX	P41279	MAP3K8	T518	T516I	516	Missense	proximal	-2	no	19.290	19.538	EPSD	COSMIC	13.250	Up-regulation
STE_STE-Unique_MAP3K8_ST	P35241	RDX	P41279	MAP3K8	T518	E522K	522	Missense	distal	4	no	19.290	17.867	EPSD	COSMIC	13.250	Down-regulation
STE_STE-Unique_MAP3K8_ST	P35241	RDX	P41279	MAP3K8	T518	E511K	511	Missense	distal	-7	no	19.290	19.451	EPSD	COSMIC	13.250	Up-regulation
STE_STE-Unique_MAP3K8_ST	P35241	RDX	P41279	MAP3K8	T518	E517K	517	Missense	proximal	-1	no	19.290	21.496	EPSD	COSMIC;GDSC;CCLE	13.250	Up-regulation
STE_STE-Unique_MAP3K8_ST	P35241	RDX	P41279	MAP3K8	T564	G571C	571	Missense	distal	7	no	27.578	27.345	PhosphoSitePlus	COSMIC	13.250	Down-regulation
STE_STE-Unique_MAP3K8_ST	P35241	RDX	P41279	MAP3K8	T564	R559C	559	Missense	distal	-5	no	27.578	27.350	PhosphoSitePlus	COSMIC	13.250	Down-regulation
STE_STE-Unique_MAP3K8_ST	P46734	MAP2K3	P41279	MAP3K8	T39	P36L	36	Missense	distal	-3	no	11.042	14.293	EPSD	COSMIC;CCLE	13.250	Gain
STE_STE-Unique_MAP3K8_ST	P46734	MAP2K3	P41279	MAP3K8	S218	L215W	215	Missense	distal	-3	no	35.996	31.368	PhosphoSitePlus	COSMIC	13.250	Down-regulation
STE_STE-Unique_MAP3K8_ST	P46734	MAP2K3	P41279	MAP3K8	S218	T222M	222	Missense	distal	4	no	35.996	33.851	PhosphoSitePlus	COSMIC	13.250	Down-regulation
STE_STE-Unique_MAP3K8_ST	P46734	MAP2K3	P41279	MAP3K8	S218	L215V	215	Missense	distal	-3	no	35.996	35.340	PhosphoSitePlus	COSMIC;GDSC;CCLE	13.250	Down-regulation
STE_STE-Unique_MAP3K8_ST	P46734	MAP2K3	P41279	MAP3K8	T222	L215W	215	Missense	distal	-7	no	14.272	14.040	EPSD	COSMIC	13.250	Down-regulation
STE_STE-Unique_MAP3K8_ST	P46734	MAP2K3	P41279	MAP3K8	T222	T222M	222	Missense	central	0	yes	14.272	0.000	EPSD	COSMIC	13.250	Loss
STE_STE-Unique_MAP3K8_ST	P46734	MAP2K3	P41279	MAP3K8	T222	K228Q	228	Missense	distal	6	no	14.272	14.903	EPSD	COSMIC	13.250	Up-regulation
STE_STE-Unique_MAP3K8_ST	P46734	MAP2K3	P41279	MAP3K8	T222	G226D	226	Missense	distal	4	no	14.272	16.003	EPSD	COSMIC;GDSC;CCLE	13.250	Up-regulation
STE_STE-Unique_MAP3K8_ST	P46734	MAP2K3	P41279	MAP3K8	T222	P229H	229	Missense	distal	7	no	14.272	14.703	EPSD	COSMIC;GDSC;CCLE	13.250	Up-regulation
STE_STE-Unique_MAP3K8_ST	P46734	MAP2K3	P41279	MAP3K8	T222	G226S	226	Missense	distal	4	no	14.272	16.270	EPSD	COSMIC;GDSC	13.250	Up-regulation
STE_STE-Unique_MAP3K8_ST	P46734	MAP2K3	P41279	MAP3K8	T222	L215V	215	Missense	distal	-7	no	14.272	14.170	EPSD	COSMIC;GDSC;CCLE	13.250	Down-regulation
STE_STE-Unique_MAP3K8_ST	Q14653	IRF3	P41279	MAP3K8	T32	I36V	36	Missense	distal	4	no	13.813	12.719	EPSD	COSMIC	13.250	Loss
STE_STE-Unique_MAP3K8_ST	Q14653	IRF3	P41279	MAP3K8	T32	K29N	29	Missense	distal	-3	no	13.813	10.120	EPSD	COSMIC;GDSC;CCLE	13.250	Loss
STE_STE-Unique_MAP3K8_ST	Q14653	IRF3	P41279	MAP3K8	S97	E94K	94	Missense	distal	-3	no	13.211	20.945	EPSD	COSMIC	13.250	Gain
STE_STE-Unique_MAP3K8_ST	Q14653	IRF3	P41279	MAP3K8	S123	P124L	124	Missense	proximal	1	no	10.753	13.762	EPSD;PhosphoSitePlus	COSMIC	13.250	Gain
STE_STE-Unique_MAP3K8_ST	Q14653	IRF3	P41279	MAP3K8	T135	D141N	141	Missense	distal	6	no	14.075	13.530	EPSD	COSMIC	13.250	Down-regulation
STE_STE-Unique_MAP3K8_ST	Q14653	IRF3	P41279	MAP3K8	T135	E137K	137	Missense	proximal	2	no	14.075	14.271	EPSD	COSMIC	13.250	Up-regulation
STE_STE-Unique_MAP3K8_ST	Q14653	IRF3	P41279	MAP3K8	T135	T132A	132	Missense	distal	-3	no	14.075	14.834	EPSD	COSMIC	13.250	Up-regulation
STE_STE-Unique_MAP3K8_ST	Q14653	IRF3	P41279	MAP3K8	S175	Q169R	169	Missense	distal	-6	no	15.760	16.080	EPSD;PhosphoSitePlus	COSMIC;CCLE	13.250	Up-regulation
STE_STE-Unique_MAP3K8_ST	Q14653	IRF3	P41279	MAP3K8	S259	R262G	262	Missense	distal	3	no	14.053	10.967	EPSD	COSMIC;GDSC;CCLE	13.250	Loss
STE_STE-Unique_MAP3K8_ST	Q14653	IRF3	P41279	MAP3K8	S259	V261E	261	Missense	proximal	2	no	14.053	13.997	EPSD	COSMIC	13.250	Down-regulation
STE_STE-Unique_MAP3K8_ST	P15311	EZR	P41279	MAP3K8	S249	R246K	246	Missense	distal	-3	no	22.102	16.231	EPSD	COSMIC	13.250	Down-regulation
STE_STE-Unique_MAP3K8_ST	P15311	EZR	P41279	MAP3K8	S249	K253R	253	Missense	distal	4	no	22.102	23.724	EPSD	COSMIC;CCLE	13.250	Up-regulation
STE_STE-Unique_MAP3K8_ST	P15311	EZR	P41279	MAP3K8	T332	V333L	333	Missense	proximal	1	no	10.689	13.583	EPSD	COSMIC	13.250	Gain
STE_STE-Unique_MAP3K8_ST	P15311	EZR	P41279	MAP3K8	T533	E537K	537	Missense	distal	4	no	20.836	19.413	EPSD	COSMIC;CCLE	13.250	Down-regulation
STE_STE-Unique_MAP3K8_ST	P15311	EZR	P41279	MAP3K8	S536	E537K	537	Missense	proximal	1	no	16.296	19.394	EPSD	COSMIC;CCLE	13.250	Up-regulation
STE_STE-Unique_MAP3K8_ST	P15311	EZR	P41279	MAP3K8	S539	E537K	537	Missense	proximal	-2	no	16.550	16.875	EPSD	COSMIC;CCLE	13.250	Up-regulation
STE_STE-Unique_MAP3K8_ST	P00519	ABL1	P41279	MAP3K8	S50	R47G	47	Missense	distal	-3	no	20.484	7.589	EPSD	COSMIC	13.250	Loss
STE_STE-Unique_MAP3K8_ST	P00519	ABL1	P41279	MAP3K8	S50	G57E	57	Missense	distal	7	no	20.484	20.314	EPSD	COSMIC	13.250	Down-regulation
STE_STE-Unique_MAP3K8_ST	P00519	ABL1	P41279	MAP3K8	S50	A56V	56	Missense	distal	6	no	20.484	20.759	EPSD	COSMIC	13.250	Up-regulation
STE_STE-Unique_MAP3K8_ST	P00519	ABL1	P41279	MAP3K8	T117	K124N	124	Missense	distal	7	no	13.586	13.800	EPSD	COSMIC	13.250	Up-regulation
STE_STE-Unique_MAP3K8_ST	P00519	ABL1	P41279	MAP3K8	S164	R166K	166	Missense	proximal	2	no	15.932	15.526	EPSD	COSMIC;CCLE	13.250	Down-regulation
STE_STE-Unique_MAP3K8_ST	P00519	ABL1	P41279	MAP3K8	S164	E168K	168	Missense	distal	4	no	15.932	14.509	EPSD	COSMIC	13.250	Down-regulation
STE_STE-Unique_MAP3K8_ST	P00519	ABL1	P41279	MAP3K8	S164	P158L	158	Missense	distal	-6	no	15.932	15.616	EPSD	COSMIC	13.250	Down-regulation
STE_STE-Unique_MAP3K8_ST	P00519	ABL1	P41279	MAP3K8	S164	S162F	162	Missense	proximal	-2	no	15.932	15.539	EPSD	COSMIC	13.250	Down-regulation
STE_STE-Unique_MAP3K8_ST	P00519	ABL1	P41279	MAP3K8	S164	Y167H	167	Missense	distal	3	no	15.932	16.062	EPSD	COSMIC	13.250	Up-regulation
STE_STE-Unique_MAP3K8_ST	P00519	ABL1	P41279	MAP3K8	T178	L184R	184	Missense	distal	6	no	24.923	25.848	EPSD	COSMIC	13.250	Up-regulation
STE_STE-Unique_MAP3K8_ST	P00519	ABL1	P41279	MAP3K8	S187	L184R	184	Missense	distal	-3	no	9.005	16.133	EPSD	COSMIC	13.250	Gain
STE_STE-Unique_MAP3K8_ST	P00519	ABL1	P41279	MAP3K8	T532	P526S	526	Missense	distal	-6	no	12.028	13.414	EPSD	COSMIC	13.250	Gain
STE_STE-Unique_MAP3K8_ST	P00519	ABL1	P41279	MAP3K8	T597	N598D	598	Missense	proximal	1	no	12.985	15.016	EPSD	COSMIC;CCLE	13.250	Gain
STE_STE-Unique_MAP3K8_ST	P00519	ABL1	P41279	MAP3K8	T597	K596R	596	Missense	proximal	-1	no	12.985	14.654	EPSD	COSMIC	13.250	Gain
STE_STE-Unique_MAP3K8_ST	P00519	ABL1	P41279	MAP3K8	S620	G626D	626	Missense	distal	6	no	13.284	14.999	EPSD	COSMIC	13.250	Up-regulation
STE_STE-Unique_MAP3K8_ST	P00519	ABL1	P41279	MAP3K8	S620	G626S	626	Missense	distal	6	no	13.284	14.039	EPSD	COSMIC	13.250	Up-regulation
STE_STE-Unique_MAP3K8_ST	P00519	ABL1	P41279	MAP3K8	S620	K616R	616	Missense	distal	-4	no	13.284	12.925	EPSD	COSMIC	13.250	Loss
STE_STE-Unique_MAP3K8_ST	P00519	ABL1	P41279	MAP3K8	T649	G644V	644	Missense	distal	-5	no	18.109	18.184	EPSD	COSMIC	13.250	Up-regulation
STE_STE-Unique_MAP3K8_ST	P00519	ABL1	P41279	MAP3K8	T649	L651W	651	Missense	proximal	2	no	18.109	17.975	EPSD	COSMIC	13.250	Down-regulation
STE_STE-Unique_MAP3K8_ST	P00519	ABL1	P41279	MAP3K8	T653	L651W	651	Missense	proximal	-2	no	15.652	15.614	EPSD	COSMIC	13.250	Down-regulation
STE_STE-Unique_MAP3K8_ST	P00519	ABL1	P41279	MAP3K8	T653	K658N	658	Missense	distal	5	no	15.652	15.801	EPSD	COSMIC	13.250	Up-regulation
STE_STE-Unique_MAP3K8_ST	P00519	ABL1	P41279	MAP3K8	S659	K658N	658	Missense	proximal	-1	no	12.753	13.476	EPSD	COSMIC	13.250	Gain
STE_STE-Unique_MAP3K8_ST	P00519	ABL1	P41279	MAP3K8	T700	G701C	701	Missense	proximal	1	no	9.526	13.513	EPSD	COSMIC	13.250	Gain
STE_STE-Unique_MAP3K8_ST	P00519	ABL1	P41279	MAP3K8	S718	G725S	725	Missense	distal	7	no	20.494	20.862	EPSD	COSMIC	13.250	Up-regulation
STE_STE-Unique_MAP3K8_ST	P00519	ABL1	P41279	MAP3K8	S718	G725V	725	Missense	distal	7	no	20.494	19.931	EPSD	COSMIC	13.250	Down-regulation
STE_STE-Unique_MAP3K8_ST	P00519	ABL1	P41279	MAP3K8	S718	H724R	724	Missense	distal	6	no	20.494	21.799	EPSD	COSMIC	13.250	Up-regulation
STE_STE-Unique_MAP3K8_ST	P00519	ABL1	P41279	MAP3K8	S718	C717F	717	Missense	proximal	-1	no	20.494	21.185	EPSD	COSMIC	13.250	Up-regulation
STE_STE-Unique_MAP3K8_ST	P00519	ABL1	P41279	MAP3K8	S718	A719T	719	Missense	proximal	1	no	20.494	19.025	EPSD	COSMIC	13.250	Down-regulation
STE_STE-Unique_MAP3K8_ST	P00519	ABL1	P41279	MAP3K8	S718	S720F	720	Missense	proximal	2	no	20.494	20.246	EPSD	COSMIC	13.250	Down-regulation
STE_STE-Unique_MAP3K8_ST	P00519	ABL1	P41279	MAP3K8	S718	V722I	722	Missense	distal	4	no	20.494	21.589	EPSD	COSMIC	13.250	Up-regulation
STE_STE-Unique_MAP3K8_ST	P00519	ABL1	P41279	MAP3K8	S720	C717F	717	Missense	distal	-3	no	12.104	13.987	EPSD	COSMIC	13.250	Gain
STE_STE-Unique_MAP3K8_ST	P00519	ABL1	P41279	MAP3K8	T735	T729M	729	Missense	distal	-6	no	34.614	33.846	PhosphoSitePlus	COSMIC	13.250	Down-regulation
STE_STE-Unique_MAP3K8_ST	P00519	ABL1	P41279	MAP3K8	T735	R732G	732	Missense	distal	-3	no	34.614	21.720	PhosphoSitePlus	COSMIC	13.250	Down-regulation
STE_STE-Unique_MAP3K8_ST	P00519	ABL1	P41279	MAP3K8	T735	R732S	732	Missense	distal	-3	no	34.614	23.508	PhosphoSitePlus	COSMIC	13.250	Down-regulation
STE_STE-Unique_MAP3K8_ST	P00519	ABL1	P41279	MAP3K8	T735	R738Q	738	Missense	distal	3	no	34.614	31.971	PhosphoSitePlus	COSMIC	13.250	Down-regulation
STE_STE-Unique_MAP3K8_ST	P00519	ABL1	P41279	MAP3K8	T735	R738W	738	Missense	distal	3	no	34.614	29.492	PhosphoSitePlus	COSMIC	13.250	Down-regulation
STE_STE-Unique_MAP3K8_ST	P00519	ABL1	P41279	MAP3K8	T751	F747I	747	Missense	distal	-4	no	15.410	15.219	EPSD	COSMIC;CCLE	13.250	Down-regulation
STE_STE-Unique_MAP3K8_ST	P00519	ABL1	P41279	MAP3K8	T751	D748N	748	Missense	distal	-3	no	15.410	16.384	EPSD	COSMIC	13.250	Up-regulation
STE_STE-Unique_MAP3K8_ST	P00519	ABL1	P41279	MAP3K8	T823	V824M	824	Missense	proximal	1	no	22.219	23.277	EPSD	COSMIC	13.250	Up-regulation
STE_STE-Unique_MAP3K8_ST	P00519	ABL1	P41279	MAP3K8	T823	R820W	820	Missense	distal	-3	no	22.219	10.462	EPSD	COSMIC;CCLE	13.250	Loss
STE_STE-Unique_MAP3K8_ST	P00519	ABL1	P41279	MAP3K8	T823	P817L	817	Missense	distal	-6	no	22.219	21.903	EPSD	COSMIC	13.250	Down-regulation
STE_STE-Unique_MAP3K8_ST	P16220	CREB1	P41279	MAP3K8	S98	S103N	103	Missense	distal	5	no	18.463	18.452	EPSD	COSMIC	13.250	Down-regulation
STE_STE-Unique_MAP3K8_ST	P16220	CREB1	P41279	MAP3K8	S98	R95I	95	Missense	distal	-3	no	18.463	10.174	EPSD	COSMIC	13.250	Loss
STE_STE-Unique_MAP3K8_ST	P16220	CREB1	P41279	MAP3K8	S98	I102M	102	Missense	distal	4	no	18.463	16.704	EPSD	COSMIC	13.250	Down-regulation
STE_STE-Unique_MAP3K8_ST	P16220	CREB1	P41279	MAP3K8	T104	S103N	103	Missense	proximal	-1	no	19.334	20.726	EPSD	COSMIC	13.250	Up-regulation
STE_STE-Unique_MAP3K8_ST	P16220	CREB1	P41279	MAP3K8	T104	E109K	109	Missense	distal	5	no	19.334	18.893	EPSD	COSMIC	13.250	Down-regulation
STE_STE-Unique_MAP3K8_ST	P16220	CREB1	P41279	MAP3K8	T104	I102M	102	Missense	proximal	-2	no	19.334	19.224	EPSD	COSMIC	13.250	Down-regulation
STE_STE-Unique_MAP3K8_ST	P16220	CREB1	P41279	MAP3K8	S111	S117N	117	Missense	distal	6	no	13.478	13.891	EPSD	COSMIC	13.250	Up-regulation
STE_STE-Unique_MAP3K8_ST	P16220	CREB1	P41279	MAP3K8	S111	V118L	118	Missense	distal	7	no	13.478	13.143	EPSD	COSMIC	13.250	Loss
STE_STE-Unique_MAP3K8_ST	P16220	CREB1	P41279	MAP3K8	S111	E109K	109	Missense	proximal	-2	no	13.478	13.803	EPSD	COSMIC	13.250	Up-regulation
STE_STE-Unique_MAP3K8_ST	P16220	CREB1	P41279	MAP3K8	S111	V118I	118	Missense	distal	7	no	13.478	13.795	EPSD	COSMIC	13.250	Up-regulation
STE_STE-Unique_MAP3K8_ST	P16220	CREB1	P41279	MAP3K8	S114	V118I	118	Missense	distal	4	no	12.820	13.915	EPSD	COSMIC	13.250	Gain
STE_STE-Unique_MAP3K8_ST	P16220	CREB1	P41279	MAP3K8	S117	V118L	118	Missense	proximal	1	no	12.483	15.378	EPSD	COSMIC	13.250	Gain
STE_STE-Unique_MAP3K8_ST	P16220	CREB1	P41279	MAP3K8	S121	S117N	117	Missense	distal	-4	no	17.077	16.912	EPSD	COSMIC	13.250	Down-regulation
STE_STE-Unique_MAP3K8_ST	P16220	CREB1	P41279	MAP3K8	S121	R124Q	124	Missense	distal	3	no	17.077	14.433	EPSD	COSMIC	13.250	Down-regulation
STE_STE-Unique_MAP3K8_ST	P16220	CREB1	P41279	MAP3K8	S121	V118L	118	Missense	distal	-3	no	17.077	17.733	EPSD	COSMIC	13.250	Up-regulation
STE_STE-Unique_MAP3K8_ST	P16220	CREB1	P41279	MAP3K8	S121	R125T	125	Missense	distal	4	no	17.077	18.402	EPSD	COSMIC	13.250	Up-regulation
STE_STE-Unique_MAP3K8_ST	P16220	CREB1	P41279	MAP3K8	S121	L128R	128	Missense	distal	7	no	17.077	17.898	EPSD	COSMIC	13.250	Up-regulation
STE_STE-Unique_MAP3K8_ST	P16220	CREB1	P41279	MAP3K8	S121	V118I	118	Missense	distal	-3	no	17.077	16.572	EPSD	COSMIC	13.250	Down-regulation
STE_STE-Unique_MAP3K8_ST	P16220	CREB1	P41279	MAP3K8	S133	L128R	128	Missense	distal	-5	no	36.386	36.659	PhosphoSitePlus	COSMIC	13.250	Up-regulation
STE_STE-Unique_MAP3K8_ST	P16220	CREB1	P41279	MAP3K8	T261	I262V	262	Missense	proximal	1	no	12.730	13.945	EPSD	COSMIC	13.250	Gain
STE_STE-Unique_MAP3K8_ST	P16220	CREB1	P41279	MAP3K8	T261	P264T	264	Missense	distal	3	no	12.730	13.288	EPSD	COSMIC;GDSC;CCLE	13.250	Gain
STE_STE-Unique_MAP3K8_ST	Q04637	EIF4G1	P41279	MAP3K8	T207	P208L	208	Missense	proximal	1	no	21.065	24.074	EPSD	COSMIC	13.250	Up-regulation
STE_STE-Unique_MAP3K8_ST	Q04637	EIF4G1	P41279	MAP3K8	T207	S204T	204	Missense	distal	-3	no	21.065	18.362	EPSD	COSMIC	13.250	Down-regulation
STE_STE-Unique_MAP3K8_ST	Q04637	EIF4G1	P41279	MAP3K8	T207	G214S	214	Missense	distal	7	no	21.065	21.432	EPSD	COSMIC	13.250	Up-regulation
STE_STE-Unique_MAP3K8_ST	Q04637	EIF4G1	P41279	MAP3K8	T207	R201C	201	Missense	distal	-6	no	21.065	20.697	EPSD	COSMIC	13.250	Down-regulation
STE_STE-Unique_MAP3K8_ST	Q04637	EIF4G1	P41279	MAP3K8	T207	R201H	201	Missense	distal	-6	no	21.065	20.600	EPSD	COSMIC	13.250	Down-regulation
STE_STE-Unique_MAP3K8_ST	Q04637	EIF4G1	P41279	MAP3K8	T207	T211M	211	Missense	distal	4	no	21.065	18.919	EPSD	COSMIC	13.250	Down-regulation
STE_STE-Unique_MAP3K8_ST	Q04637	EIF4G1	P41279	MAP3K8	S257	E256K	256	Missense	proximal	-1	no	13.151	15.357	EPSD	COSMIC	13.250	Gain
STE_STE-Unique_MAP3K8_ST	Q04637	EIF4G1	P41279	MAP3K8	S257	P250S	250	Missense	distal	-7	no	13.151	13.351	EPSD	COSMIC	13.250	Gain
STE_STE-Unique_MAP3K8_ST	Q04637	EIF4G1	P41279	MAP3K8	S257	P264S	264	Missense	distal	7	no	13.151	14.146	EPSD	COSMIC	13.250	Gain
STE_STE-Unique_MAP3K8_ST	Q04637	EIF4G1	P41279	MAP3K8	S766	L768M	768	Missense	proximal	2	no	18.261	18.388	EPSD	COSMIC	13.250	Up-regulation
STE_STE-Unique_MAP3K8_ST	Q04637	EIF4G1	P41279	MAP3K8	S766	S766F	766	Missense	central	0	yes	18.261	0.000	EPSD	COSMIC	13.250	Loss
STE_STE-Unique_MAP3K8_ST	Q04637	EIF4G1	P41279	MAP3K8	S766	R762H	762	Missense	distal	-4	no	18.261	18.441	EPSD	COSMIC;CCLE	13.250	Up-regulation
STE_STE-Unique_MAP3K8_ST	Q04637	EIF4G1	P41279	MAP3K8	S766	L771P	771	Missense	distal	5	no	18.261	18.602	EPSD	COSMIC	13.250	Up-regulation
STE_STE-Unique_MAP3K8_ST	Q04637	EIF4G1	P41279	MAP3K8	S766	D759Y	759	Missense	distal	-7	no	18.261	18.024	EPSD	COSMIC	13.250	Down-regulation
STE_STE-Unique_MAP3K8_ST	Q04637	EIF4G1	P41279	MAP3K8	S766	R763H	763	Missense	distal	-3	no	18.261	7.351	EPSD	COSMIC	13.250	Loss
STE_STE-Unique_MAP3K8_ST	Q04637	EIF4G1	P41279	MAP3K8	S895	G897E	897	Missense	proximal	2	no	22.386	22.473	EPSD	COSMIC	13.250	Up-regulation
STE_STE-Unique_MAP3K8_ST	Q04637	EIF4G1	P41279	MAP3K8	S895	G897R	897	Missense	proximal	2	no	22.386	23.076	EPSD	COSMIC;GDSC	13.250	Up-regulation
STE_STE-Unique_MAP3K8_ST	Q04637	EIF4G1	P41279	MAP3K8	S895	R888Q	888	Missense	distal	-7	no	22.386	22.056	EPSD	COSMIC	13.250	Down-regulation
STE_STE-Unique_MAP3K8_ST	Q04637	EIF4G1	P41279	MAP3K8	S895	R894C	894	Missense	proximal	-1	no	22.386	19.608	EPSD	COSMIC	13.250	Down-regulation
STE_STE-Unique_MAP3K8_ST	Q04637	EIF4G1	P41279	MAP3K8	S895	R893W	893	Missense	proximal	-2	no	22.386	21.444	EPSD	COSMIC	13.250	Down-regulation
STE_STE-Unique_MAP3K8_ST	Q04637	EIF4G1	P41279	MAP3K8	S895	I890V	890	Missense	distal	-5	no	22.386	22.432	EPSD	COSMIC	13.250	Up-regulation
STE_STE-Unique_MAP3K8_ST	Q04637	EIF4G1	P41279	MAP3K8	S895	R894H	894	Missense	proximal	-1	no	22.386	18.900	EPSD	COSMIC;GDSC;CCLE	13.250	Down-regulation
STE_STE-Unique_MAP3K8_ST	Q04637	EIF4G1	P41279	MAP3K8	S895	I902V	902	Missense	distal	7	no	22.386	22.069	EPSD	COSMIC	13.250	Down-regulation
STE_STE-Unique_MAP3K8_ST	Q04637	EIF4G1	P41279	MAP3K8	S895	R888H	888	Missense	distal	-7	no	22.386	21.851	EPSD	COSMIC	13.250	Down-regulation
STE_STE-Unique_MAP3K8_ST	Q04637	EIF4G1	P41279	MAP3K8	S895	R894W	894	Missense	proximal	-1	no	22.386	19.476	EPSD	COSMIC	13.250	Down-regulation
STE_STE-Unique_MAP3K8_ST	Q04637	EIF4G1	P41279	MAP3K8	S895	L896P	896	Missense	proximal	1	no	22.386	19.377	EPSD	COSMIC	13.250	Down-regulation
STE_STE-Unique_MAP3K8_ST	Q04637	EIF4G1	P41279	MAP3K8	S1077	T1073P	1073	Missense	distal	-4	no	18.640	18.968	EPSD	COSMIC	13.250	Up-regulation
STE_STE-Unique_MAP3K8_ST	Q04637	EIF4G1	P41279	MAP3K8	S1077	L1084R	1084	Missense	distal	7	no	18.640	19.462	EPSD	COSMIC	13.250	Up-regulation
STE_STE-Unique_MAP3K8_ST	Q04637	EIF4G1	P41279	MAP3K8	S1077	S1077F	1077	Missense	central	0	yes	18.640	0.000	EPSD	COSMIC	13.250	Loss
STE_STE-Unique_MAP3K8_ST	Q04637	EIF4G1	P41279	MAP3K8	S1077	S1077P	1077	Missense	central	0	yes	18.640	0.000	EPSD	COSMIC	13.250	Loss
STE_STE-Unique_MAP3K8_ST	Q04637	EIF4G1	P41279	MAP3K8	T1117	S1118R	1118	Missense	proximal	1	no	9.727	15.708	EPSD	COSMIC	13.250	Gain
STE_STE-Unique_MAP3K8_ST	Q04637	EIF4G1	P41279	MAP3K8	S1124	T1117A	1117	Missense	distal	-7	no	13.419	13.324	EPSD	COSMIC	13.250	Down-regulation
STE_STE-Unique_MAP3K8_ST	Q04637	EIF4G1	P41279	MAP3K8	S1124	S1118R	1118	Missense	distal	-6	no	13.419	13.030	EPSD	COSMIC	13.250	Loss
STE_STE-Unique_MAP3K8_ST	Q04637	EIF4G1	P41279	MAP3K8	S1124	A1125S	1125	Missense	proximal	1	no	13.419	13.476	EPSD	COSMIC	13.250	Up-regulation
STE_STE-Unique_MAP3K8_ST	Q04637	EIF4G1	P41279	MAP3K8	S1124	R1122H	1122	Missense	proximal	-2	no	13.419	12.619	EPSD	COSMIC	13.250	Loss
STE_STE-Unique_MAP3K8_ST	Q04637	EIF4G1	P41279	MAP3K8	S1124	A1129V	1129	Missense	distal	5	no	13.419	12.927	EPSD	COSMIC	13.250	Loss
STE_STE-Unique_MAP3K8_ST	Q04637	EIF4G1	P41279	MAP3K8	S1144	R1150M	1150	Missense	distal	6	no	17.636	16.379	EPSD	COSMIC	13.250	Down-regulation
STE_STE-Unique_MAP3K8_ST	Q04637	EIF4G1	P41279	MAP3K8	S1144	R1139H	1139	Missense	distal	-5	no	17.636	17.436	EPSD	COSMIC	13.250	Down-regulation
STE_STE-Unique_MAP3K8_ST	Q04637	EIF4G1	P41279	MAP3K8	S1144	E1149Q	1149	Missense	distal	5	no	17.636	17.284	EPSD	COSMIC	13.250	Down-regulation
STE_STE-Unique_MAP3K8_ST	Q04637	EIF4G1	P41279	MAP3K8	S1144	R1143M	1143	Missense	proximal	-1	no	17.636	14.948	EPSD	COSMIC	13.250	Down-regulation
STE_STE-Unique_MAP3K8_ST	Q04637	EIF4G1	P41279	MAP3K8	S1144	G1151D	1151	Missense	distal	7	no	17.636	17.515	EPSD	COSMIC	13.250	Down-regulation
STE_STE-Unique_MAP3K8_ST	Q04637	EIF4G1	P41279	MAP3K8	S1144	R1148Q	1148	Missense	distal	4	no	17.636	17.170	EPSD	COSMIC	13.250	Down-regulation
STE_STE-Unique_MAP3K8_ST	Q04637	EIF4G1	P41279	MAP3K8	S1145	R1150M	1150	Missense	distal	5	no	19.747	20.081	EPSD	COSMIC	13.250	Up-regulation
STE_STE-Unique_MAP3K8_ST	Q04637	EIF4G1	P41279	MAP3K8	S1145	R1139H	1139	Missense	distal	-6	no	19.747	19.282	EPSD	COSMIC	13.250	Down-regulation
STE_STE-Unique_MAP3K8_ST	Q04637	EIF4G1	P41279	MAP3K8	S1145	E1152K	1152	Missense	distal	7	no	19.747	19.614	EPSD	COSMIC	13.250	Down-regulation
STE_STE-Unique_MAP3K8_ST	Q04637	EIF4G1	P41279	MAP3K8	S1145	E1149Q	1149	Missense	distal	4	no	19.747	19.479	EPSD	COSMIC	13.250	Down-regulation
STE_STE-Unique_MAP3K8_ST	Q04637	EIF4G1	P41279	MAP3K8	S1145	R1143M	1143	Missense	proximal	-2	no	19.747	19.127	EPSD	COSMIC	13.250	Down-regulation
STE_STE-Unique_MAP3K8_ST	Q04637	EIF4G1	P41279	MAP3K8	S1145	G1151D	1151	Missense	distal	6	no	19.747	21.461	EPSD	COSMIC	13.250	Up-regulation
STE_STE-Unique_MAP3K8_ST	Q04637	EIF4G1	P41279	MAP3K8	S1145	R1148Q	1148	Missense	distal	3	no	19.747	17.103	EPSD	COSMIC	13.250	Down-regulation
STE_STE-Unique_MAP3K8_ST	Q04637	EIF4G1	P41279	MAP3K8	S1147	R1150M	1150	Missense	distal	3	no	25.856	21.099	PhosphoSitePlus	COSMIC	13.250	Down-regulation
STE_STE-Unique_MAP3K8_ST	Q04637	EIF4G1	P41279	MAP3K8	S1147	A1154D	1154	Missense	distal	7	no	25.856	25.977	PhosphoSitePlus	COSMIC	13.250	Up-regulation
STE_STE-Unique_MAP3K8_ST	Q04637	EIF4G1	P41279	MAP3K8	S1147	E1152K	1152	Missense	distal	5	no	25.856	25.415	PhosphoSitePlus	COSMIC	13.250	Down-regulation
STE_STE-Unique_MAP3K8_ST	Q04637	EIF4G1	P41279	MAP3K8	S1147	E1149Q	1149	Missense	proximal	2	no	25.856	26.011	PhosphoSitePlus	COSMIC	13.250	Up-regulation
STE_STE-Unique_MAP3K8_ST	Q04637	EIF4G1	P41279	MAP3K8	S1147	R1143M	1143	Missense	distal	-4	no	25.856	26.320	PhosphoSitePlus	COSMIC	13.250	Up-regulation
STE_STE-Unique_MAP3K8_ST	Q04637	EIF4G1	P41279	MAP3K8	S1147	G1151D	1151	Missense	distal	4	no	25.856	27.587	PhosphoSitePlus	COSMIC	13.250	Up-regulation
STE_STE-Unique_MAP3K8_ST	Q04637	EIF4G1	P41279	MAP3K8	S1147	R1148Q	1148	Missense	proximal	1	no	25.856	23.148	PhosphoSitePlus	COSMIC	13.250	Down-regulation
STE_STE-Unique_MAP3K8_ST	Q04637	EIF4G1	P41279	MAP3K8	S1147	A1154S	1154	Missense	distal	7	no	25.856	26.466	PhosphoSitePlus	COSMIC	13.250	Up-regulation
STE_STE-Unique_MAP3K8_ST	Q04637	EIF4G1	P41279	MAP3K8	S1147	A1154V	1154	Missense	distal	7	no	25.856	25.535	PhosphoSitePlus	COSMIC	13.250	Down-regulation
STE_STE-Unique_MAP3K8_ST	Q04637	EIF4G1	P41279	MAP3K8	S1164	E1162K	1162	Missense	proximal	-2	no	15.969	16.295	EPSD	COSMIC	13.250	Up-regulation
STE_STE-Unique_MAP3K8_ST	Q04637	EIF4G1	P41279	MAP3K8	S1164	R1160S	1160	Missense	distal	-4	no	15.969	15.632	EPSD	COSMIC	13.250	Down-regulation
STE_STE-Unique_MAP3K8_ST	Q04637	EIF4G1	P41279	MAP3K8	S1164	R1170H	1170	Missense	distal	6	no	15.969	14.664	EPSD	COSMIC;GDSC	13.250	Down-regulation
STE_STE-Unique_MAP3K8_ST	Q04637	EIF4G1	P41279	MAP3K8	S1164	R1166W	1166	Missense	proximal	2	no	15.969	15.289	EPSD	COSMIC	13.250	Down-regulation
STE_STE-Unique_MAP3K8_ST	Q04637	EIF4G1	P41279	MAP3K8	S1164	R1160P	1160	Missense	distal	-4	no	15.969	16.327	EPSD	COSMIC	13.250	Up-regulation
STE_STE-Unique_MAP3K8_ST	Q04637	EIF4G1	P41279	MAP3K8	S1164	R1170C	1170	Missense	distal	6	no	15.969	14.698	EPSD	COSMIC	13.250	Down-regulation
STE_STE-Unique_MAP3K8_ST	Q04637	EIF4G1	P41279	MAP3K8	S1164	R1157W	1157	Missense	distal	-7	no	15.969	15.412	EPSD	COSMIC	13.250	Down-regulation
STE_STE-Unique_MAP3K8_ST	Q04637	EIF4G1	P41279	MAP3K8	S1164	E1165D	1165	Missense	proximal	1	no	15.969	19.860	EPSD	COSMIC	13.250	Up-regulation
STE_STE-Unique_MAP3K8_ST	Q04637	EIF4G1	P41279	MAP3K8	S1164	E1165Q	1165	Missense	proximal	1	no	15.969	20.738	EPSD	COSMIC	13.250	Up-regulation
STE_STE-Unique_MAP3K8_ST	Q04637	EIF4G1	P41279	MAP3K8	S1164	R1166C	1166	Missense	proximal	2	no	15.969	15.441	EPSD	COSMIC	13.250	Down-regulation
STE_STE-Unique_MAP3K8_ST	Q04637	EIF4G1	P41279	MAP3K8	T1179	R1173W	1173	Missense	distal	-6	no	26.900	26.203	EPSD	COSMIC	13.250	Down-regulation
STE_STE-Unique_MAP3K8_ST	Q04637	EIF4G1	P41279	MAP3K8	T1179	T1182I	1182	Missense	distal	3	no	26.900	26.562	EPSD	COSMIC	13.250	Down-regulation
STE_STE-Unique_MAP3K8_ST	Q04637	EIF4G1	P41279	MAP3K8	T1179	A1177G	1177	Missense	proximal	-2	no	26.900	27.276	EPSD	COSMIC	13.250	Up-regulation
STE_STE-Unique_MAP3K8_ST	Q04637	EIF4G1	P41279	MAP3K8	T1179	D1175Y	1175	Missense	distal	-4	no	26.900	27.682	EPSD	COSMIC	13.250	Up-regulation
STE_STE-Unique_MAP3K8_ST	Q04637	EIF4G1	P41279	MAP3K8	T1179	A1177V	1177	Missense	proximal	-2	no	26.900	27.006	EPSD	COSMIC	13.250	Up-regulation
STE_STE-Unique_MAP3K8_ST	Q04637	EIF4G1	P41279	MAP3K8	T1179	R1176C	1176	Missense	distal	-3	no	26.900	16.445	EPSD	COSMIC	13.250	Down-regulation
STE_STE-Unique_MAP3K8_ST	Q04637	EIF4G1	P41279	MAP3K8	T1179	R1178W	1178	Missense	proximal	-1	no	26.900	23.990	EPSD	COSMIC	13.250	Down-regulation
STE_STE-Unique_MAP3K8_ST	Q04637	EIF4G1	P41279	MAP3K8	T1179	L1174F	1174	Missense	distal	-5	no	26.900	26.954	EPSD	COSMIC	13.250	Up-regulation
STE_STE-Unique_MAP3K8_ST	Q04637	EIF4G1	P41279	MAP3K8	T1182	T1182I	1182	Missense	central	0	yes	16.543	0.000	EPSD	COSMIC	13.250	Loss
STE_STE-Unique_MAP3K8_ST	Q04637	EIF4G1	P41279	MAP3K8	T1182	A1177G	1177	Missense	distal	-5	no	16.543	16.534	EPSD	COSMIC	13.250	Down-regulation
STE_STE-Unique_MAP3K8_ST	Q04637	EIF4G1	P41279	MAP3K8	T1182	D1175Y	1175	Missense	distal	-7	no	16.543	16.307	EPSD	COSMIC	13.250	Down-regulation
STE_STE-Unique_MAP3K8_ST	Q04637	EIF4G1	P41279	MAP3K8	T1182	A1177V	1177	Missense	distal	-5	no	16.543	16.609	EPSD	COSMIC	13.250	Up-regulation
STE_STE-Unique_MAP3K8_ST	Q04637	EIF4G1	P41279	MAP3K8	T1182	R1176C	1176	Missense	distal	-6	no	16.543	16.176	EPSD	COSMIC	13.250	Down-regulation
STE_STE-Unique_MAP3K8_ST	Q04637	EIF4G1	P41279	MAP3K8	T1182	R1178W	1178	Missense	distal	-4	no	16.543	16.945	EPSD	COSMIC	13.250	Up-regulation
STE_STE-Unique_MAP3K8_ST	Q04637	EIF4G1	P41279	MAP3K8	T1182	S1187F	1187	Missense	distal	5	no	16.543	16.584	EPSD	COSMIC	13.250	Up-regulation
STE_STE-Unique_MAP3K8_ST	Q04637	EIF4G1	P41279	MAP3K8	T1182	S1187P	1187	Missense	distal	5	no	16.543	16.695	EPSD	COSMIC	13.250	Up-regulation
STE_STE-Unique_MAP3K8_ST	Q04637	EIF4G1	P41279	MAP3K8	S1185	T1182I	1182	Missense	distal	-3	no	13.858	19.378	EPSD	COSMIC	13.250	Up-regulation
STE_STE-Unique_MAP3K8_ST	Q04637	EIF4G1	P41279	MAP3K8	S1185	E1191D	1191	Missense	distal	6	no	13.858	15.423	EPSD	COSMIC	13.250	Up-regulation
STE_STE-Unique_MAP3K8_ST	Q04637	EIF4G1	P41279	MAP3K8	S1185	R1178W	1178	Missense	distal	-7	no	13.858	13.301	EPSD	COSMIC	13.250	Down-regulation
STE_STE-Unique_MAP3K8_ST	Q04637	EIF4G1	P41279	MAP3K8	S1185	S1187F	1187	Missense	proximal	2	no	13.858	13.610	EPSD	COSMIC	13.250	Down-regulation
STE_STE-Unique_MAP3K8_ST	Q04637	EIF4G1	P41279	MAP3K8	S1185	S1187P	1187	Missense	proximal	2	no	13.858	13.598	EPSD	COSMIC	13.250	Down-regulation
STE_STE-Unique_MAP3K8_ST	Q04637	EIF4G1	P41279	MAP3K8	S1185	E1192D	1192	Missense	distal	7	no	13.858	13.906	EPSD	COSMIC	13.250	Up-regulation
STE_STE-Unique_MAP3K8_ST	Q04637	EIF4G1	P41279	MAP3K8	S1187	T1182I	1182	Missense	distal	-5	no	25.950	25.968	EPSD	COSMIC	13.250	Up-regulation
STE_STE-Unique_MAP3K8_ST	Q04637	EIF4G1	P41279	MAP3K8	S1187	R1193Q	1193	Missense	distal	6	no	25.950	25.270	EPSD	COSMIC	13.250	Down-regulation
STE_STE-Unique_MAP3K8_ST	Q04637	EIF4G1	P41279	MAP3K8	S1187	R1193W	1193	Missense	distal	6	no	25.950	24.787	EPSD	COSMIC	13.250	Down-regulation
STE_STE-Unique_MAP3K8_ST	Q04637	EIF4G1	P41279	MAP3K8	S1187	E1191D	1191	Missense	distal	4	no	25.950	28.160	EPSD	COSMIC	13.250	Up-regulation
STE_STE-Unique_MAP3K8_ST	Q04637	EIF4G1	P41279	MAP3K8	S1187	S1187F	1187	Missense	central	0	yes	25.950	0.000	EPSD	COSMIC	13.250	Loss
STE_STE-Unique_MAP3K8_ST	Q04637	EIF4G1	P41279	MAP3K8	S1187	S1187P	1187	Missense	central	0	yes	25.950	0.000	EPSD	COSMIC	13.250	Loss
STE_STE-Unique_MAP3K8_ST	Q04637	EIF4G1	P41279	MAP3K8	S1187	E1192D	1192	Missense	distal	5	no	25.950	25.666	EPSD	COSMIC	13.250	Down-regulation
STE_STE-Unique_MAP3K8_ST	Q04637	EIF4G1	P41279	MAP3K8	S1194	R1193Q	1193	Missense	proximal	-1	no	14.389	12.034	EPSD	COSMIC	13.250	Loss
STE_STE-Unique_MAP3K8_ST	Q04637	EIF4G1	P41279	MAP3K8	S1194	R1193W	1193	Missense	proximal	-1	no	14.389	11.480	EPSD	COSMIC	13.250	Loss
STE_STE-Unique_MAP3K8_ST	Q04637	EIF4G1	P41279	MAP3K8	S1194	E1191D	1191	Missense	distal	-3	no	14.389	17.456	EPSD	COSMIC	13.250	Up-regulation
STE_STE-Unique_MAP3K8_ST	Q04637	EIF4G1	P41279	MAP3K8	S1194	R1197W	1197	Missense	distal	3	no	14.389	9.268	EPSD	COSMIC	13.250	Loss
STE_STE-Unique_MAP3K8_ST	Q04637	EIF4G1	P41279	MAP3K8	S1194	P1198L	1198	Missense	distal	4	no	14.389	14.227	EPSD	COSMIC	13.250	Down-regulation
STE_STE-Unique_MAP3K8_ST	Q04637	EIF4G1	P41279	MAP3K8	S1194	S1187F	1187	Missense	distal	-7	no	14.389	14.371	EPSD	COSMIC	13.250	Down-regulation
STE_STE-Unique_MAP3K8_ST	Q04637	EIF4G1	P41279	MAP3K8	S1194	S1187P	1187	Missense	distal	-7	no	14.389	14.190	EPSD	COSMIC	13.250	Down-regulation
STE_STE-Unique_MAP3K8_ST	Q04637	EIF4G1	P41279	MAP3K8	S1194	E1192D	1192	Missense	proximal	-2	no	14.389	14.746	EPSD	COSMIC	13.250	Up-regulation
STE_STE-Unique_MAP3K8_ST	Q04637	EIF4G1	P41279	MAP3K8	S1209	R1214W	1214	Missense	distal	5	no	12.449	13.302	EPSD	COSMIC	13.250	Gain
STE_STE-Unique_MAP3K8_ST	Q04637	EIF4G1	P41279	MAP3K8	S1209	E1212K	1212	Missense	distal	3	no	12.449	13.415	EPSD	COSMIC	13.250	Gain
STE_STE-Unique_MAP3K8_ST	Q04637	EIF4G1	P41279	MAP3K8	T1495	I1491V	1491	Missense	distal	-4	no	14.057	13.918	EPSD	COSMIC	13.250	Down-regulation
STE_STE-Unique_MAP3K8_ST	Q04637	EIF4G1	P41279	MAP3K8	T1495	P1496L	1496	Missense	proximal	1	no	14.057	17.066	EPSD	COSMIC	13.250	Up-regulation
STE_STE-Unique_MAP3K8_ST	Q04637	EIF4G1	P41279	MAP3K8	T1495	I1491T	1491	Missense	distal	-4	no	14.057	13.640	EPSD	COSMIC	13.250	Down-regulation
STE_STE-Unique_MAP3K8_ST	Q04637	EIF4G1	P41279	MAP3K8	T1495	I1491N	1491	Missense	distal	-4	no	14.057	13.108	EPSD	COSMIC	13.250	Loss
STE_STE-Unique_MAP3K8_ST	Q04637	EIF4G1	P41279	MAP3K8	T1495	D1500G	1500	Missense	distal	5	no	14.057	14.380	EPSD	COSMIC	13.250	Up-regulation
STE_STE-Unique_MAP3K8_ST	Q04637	EIF4G1	P41279	MAP3K8	T1495	I1492N	1492	Missense	distal	-3	no	14.057	12.782	EPSD	COSMIC	13.250	Loss
STE_STE-Unique_MAP3K8_ST	Q04637	EIF4G1	P41279	MAP3K8	T1495	I1492T	1492	Missense	distal	-3	no	14.057	8.538	EPSD	COSMIC	13.250	Loss
STE_STE-Unique_MAP3K8_ST	Q04637	EIF4G1	P41279	MAP3K8	T1495	I1492V	1492	Missense	distal	-3	no	14.057	14.562	EPSD	COSMIC	13.250	Up-regulation
STE_STE-Unique_MAP3K8_ST	Q04637	EIF4G1	P41279	MAP3K8	T1495	T1495N	1495	Missense	central	0	yes	14.057	0.000	EPSD	COSMIC	13.250	Loss
STE_STE-Unique_MAP3K8_ST	P52564	MAP2K6	P41279	MAP3K8	S207	D213Y	213	Missense	distal	6	no	36.275	34.647	PhosphoSitePlus	COSMIC	13.250	Down-regulation
STE_STE-Unique_MAP3K8_ST	Q13541	EIF4EBP1	P41279	MAP3K8	T70	P72S	72	Missense	proximal	2	no	22.215	22.475	PhosphoSitePlus	COSMIC	13.250	Up-regulation
STE_STE-Unique_MAP3K8_ST	Q13541	EIF4EBP1	P41279	MAP3K8	T70	R63W	63	Missense	distal	-7	no	22.215	21.658	PhosphoSitePlus	COSMIC	13.250	Down-regulation
STE_STE-Unique_MAP3K8_ST	P53350	PLK1	P41279	MAP3K8	T210	G205V	205	Missense	distal	-5	no	36.192	36.267	PhosphoSitePlus;EPSD	COSMIC	13.250	Up-regulation
STE_STE-Unique_MAP3K8_ST	Q02750	MAP2K1	P41279	MAP3K8	S218	S212N	212	Missense	distal	-6	no	35.306	34.909	EPSD;PhosphoSitePlus	COSMIC	13.250	Down-regulation
STE_STE-Unique_MAP3K8_ST	Q02750	MAP2K1	P41279	MAP3K8	S218	L215F	215	Missense	distal	-3	no	35.306	33.862	EPSD;PhosphoSitePlus	COSMIC	13.250	Down-regulation
STE_STE-Unique_MAP3K8_ST	Q02750	MAP2K1	P41279	MAP3K8	S218	G213V	213	Missense	distal	-5	no	35.306	35.381	EPSD;PhosphoSitePlus	COSMIC	13.250	Up-regulation
STE_STE-Unique_MAP3K8_ST	Q02750	MAP2K1	P41279	MAP3K8	S218	S218F	218	Missense	central	0	yes	35.306	0.000	EPSD;PhosphoSitePlus	COSMIC	13.250	Loss
STE_STE-Unique_MAP3K8_ST	Q02750	MAP2K1	P41279	MAP3K8	S222	L215F	215	Missense	distal	-7	no	29.794	29.834	PhosphoSitePlus;EPSD	COSMIC	13.250	Up-regulation
STE_STE-Unique_MAP3K8_ST	Q02750	MAP2K1	P41279	MAP3K8	S222	Y229H	229	Missense	distal	7	no	29.794	29.735	PhosphoSitePlus;EPSD	COSMIC	13.250	Down-regulation
STE_STE-Unique_MAP3K8_ST	Q02750	MAP2K1	P41279	MAP3K8	S222	S218F	218	Missense	distal	-4	no	29.794	30.769	PhosphoSitePlus;EPSD	COSMIC	13.250	Up-regulation
STE_STE-Unique_MAP3K8_ST	Q02750	MAP2K1	P41279	MAP3K8	S231	Y229H	229	Missense	proximal	-2	no	15.435	15.458	EPSD	COSMIC	13.250	Up-regulation
STE_STE-Unique_MAP3K8_ST	Q15418	RPS6KA1	P41279	MAP3K8	T83	R84Q	84	Missense	proximal	1	no	22.852	20.144	EPSD	COSMIC	13.250	Down-regulation
STE_STE-Unique_MAP3K8_ST	Q15418	RPS6KA1	P41279	MAP3K8	T83	R80Q	80	Missense	distal	-3	no	22.852	14.077	EPSD	COSMIC	13.250	Down-regulation
STE_STE-Unique_MAP3K8_ST	Q15418	RPS6KA1	P41279	MAP3K8	S221	E216K	216	Missense	distal	-5	no	19.660	19.733	EPSD	COSMIC	13.250	Up-regulation
STE_STE-Unique_MAP3K8_ST	Q15418	RPS6KA1	P41279	MAP3K8	S221	H215R	215	Missense	distal	-6	no	19.660	20.125	EPSD	COSMIC	13.250	Up-regulation
STE_STE-Unique_MAP3K8_ST	Q15418	RPS6KA1	P41279	MAP3K8	S221	G224R	224	Missense	distal	3	no	19.660	22.746	EPSD	COSMIC	13.250	Up-regulation
STE_STE-Unique_MAP3K8_ST	Q15418	RPS6KA1	P41279	MAP3K8	S221	H215P	215	Missense	distal	-6	no	19.660	19.128	EPSD	COSMIC	13.250	Down-regulation
STE_STE-Unique_MAP3K8_ST	Q15418	RPS6KA1	P41279	MAP3K8	S221	S221A	221	Missense	central	0	yes	19.660	0.000	EPSD	COSMIC	13.250	Loss
STE_STE-Unique_MAP3K8_ST	Q15418	RPS6KA1	P41279	MAP3K8	S380	G385S	385	Missense	distal	5	no	28.230	27.909	PhosphoSitePlus	COSMIC	13.250	Down-regulation
STE_STE-Unique_MAP3K8_ST	Q15418	RPS6KA1	P41279	MAP3K8	S513	H517N	517	Missense	distal	4	no	12.012	13.297	EPSD	COSMIC	13.250	Gain
STE_STE-Unique_MAP3K8_ST	Q15418	RPS6KA1	P41279	MAP3K8	T522	H517N	517	Missense	distal	-5	no	13.574	13.647	EPSD	COSMIC	13.250	Up-regulation
STE_STE-Unique_MAP3K8_ST	Q15418	RPS6KA1	P41279	MAP3K8	T522	V515F	515	Missense	distal	-7	no	13.574	13.715	EPSD	COSMIC	13.250	Up-regulation
STE_STE-Unique_MAP3K8_ST	Q15418	RPS6KA1	P41279	MAP3K8	T522	S528C	528	Missense	distal	6	no	13.574	12.944	EPSD	COSMIC	13.250	Loss
STE_STE-Unique_MAP3K8_ST	Q15418	RPS6KA1	P41279	MAP3K8	T522	E524Q	524	Missense	proximal	2	no	13.574	13.728	EPSD	COSMIC	13.250	Up-regulation
STE_STE-Unique_MAP3K8_ST	Q15418	RPS6KA1	P41279	MAP3K8	T522	E524G	524	Missense	proximal	2	no	13.574	13.486	EPSD	COSMIC	13.250	Down-regulation
STE_STE-Unique_MAP3K8_ST	Q15418	RPS6KA1	P41279	MAP3K8	T522	G520D	520	Missense	proximal	-2	no	13.574	13.648	EPSD	COSMIC	13.250	Up-regulation
STE_STE-Unique_MAP3K8_ST	Q15418	RPS6KA1	P41279	MAP3K8	T522	V515D	515	Missense	distal	-7	no	13.574	13.724	EPSD	COSMIC	13.250	Up-regulation
STE_STE-Unique_MAP3K8_ST	Q15418	RPS6KA1	P41279	MAP3K8	T573	A566V	566	Missense	distal	-7	no	25.722	25.981	EPSD	COSMIC	13.250	Up-regulation
STE_STE-Unique_MAP3K8_ST	Q15418	RPS6KA1	P41279	MAP3K8	T573	G569E	569	Missense	distal	-4	no	25.722	25.881	EPSD	COSMIC	13.250	Up-regulation
STE_STE-Unique_MAP3K8_ST	Q15418	RPS6KA1	P41279	MAP3K8	T573	T577A	577	Missense	distal	4	no	25.722	23.993	EPSD	COSMIC	13.250	Down-regulation
STE_STE-Unique_MAP3K8_ST	Q15418	RPS6KA1	P41279	MAP3K8	T643	G639V	639	Missense	distal	-4	no	18.329	18.678	EPSD	COSMIC	13.250	Up-regulation
STE_STE-Unique_MAP3K8_ST	Q15418	RPS6KA1	P41279	MAP3K8	T643	L636P	636	Missense	distal	-7	no	18.329	18.188	EPSD	COSMIC	13.250	Down-regulation
STE_STE-Unique_MAP3K8_ST	Q15418	RPS6KA1	P41279	MAP3K8	T643	W641C	641	Missense	proximal	-2	no	18.329	18.589	EPSD	COSMIC	13.250	Up-regulation
STE_STE-Unique_MAP3K8_ST	P26038	MSN	P41279	MAP3K8	S249	S249C	249	Missense	central	0	yes	23.574	0.000	EPSD	COSMIC	13.250	Loss
STE_STE-Unique_MAP3K8_ST	P26038	MSN	P41279	MAP3K8	S249	F255C	255	Missense	distal	6	no	23.574	23.224	EPSD	COSMIC	13.250	Down-regulation
STE_STE-Unique_MAP3K8_ST	P26038	MSN	P41279	MAP3K8	S249	K254N	254	Missense	distal	5	no	23.574	23.722	EPSD	COSMIC	13.250	Up-regulation
STE_STE-Unique_MAP3K8_ST	P26038	MSN	P41279	MAP3K8	S504	A498V	498	Missense	distal	-6	no	21.992	21.650	EPSD	COSMIC	13.250	Down-regulation
STE_STE-Unique_MAP3K8_ST	P26038	MSN	P41279	MAP3K8	S504	R508H	508	Missense	distal	4	no	21.992	21.694	EPSD	COSMIC	13.250	Down-regulation
STE_STE-Unique_MAP3K8_ST	P26038	MSN	P41279	MAP3K8	T509	K514M	514	Missense	distal	5	no	15.995	15.881	EPSD	COSMIC	13.250	Down-regulation
STE_STE-Unique_MAP3K8_ST	P26038	MSN	P41279	MAP3K8	T509	R508H	508	Missense	proximal	-1	no	15.995	12.509	EPSD	COSMIC	13.250	Loss
STE_STE-Unique_MAP3K8_ST	P26038	MSN	P41279	MAP3K8	T509	N515K	515	Missense	distal	6	no	15.995	14.912	EPSD	COSMIC	13.250	Down-regulation
STE_STE-Unique_MAP3K8_ST	P26038	MSN	P41279	MAP3K8	T526	L529Q	529	Missense	distal	3	no	9.511	14.762	EPSD	COSMIC	13.250	Gain
STE_STE-Unique_MAP3K8_ST	P26038	MSN	P41279	MAP3K8	S536	L529Q	529	Missense	distal	-7	no	13.986	13.981	EPSD	COSMIC	13.250	Down-regulation
STE_STE-Unique_MAP3K8_ST	P26038	MSN	P41279	MAP3K8	T558	R560H	560	Missense	proximal	2	no	29.457	28.798	PhosphoSitePlus	COSMIC;GDSC;CCLE	13.250	Down-regulation
STE_STE-Unique_MAP3K8_ST	P26038	MSN	P41279	MAP3K8	T558	K555R	555	Missense	distal	-3	no	29.457	35.328	PhosphoSitePlus	COSMIC	13.250	Up-regulation
STE_STE-Unique_MAP3K8_ST	P06493	CDK1	P41279	MAP3K8	S53	S53C	53	Missense	central	0	yes	16.506	0.000	EPSD	COSMIC	13.250	Loss
STE_STE-Unique_MAP3K8_ST	P06493	CDK1	P41279	MAP3K8	S248	A250V	250	Missense	proximal	2	no	14.692	14.995	EPSD	COSMIC;GDSC;CCLE	13.250	Up-regulation
STE_STE-Unique_MAP3K8_ST	P36507	MAP2K2	P41279	MAP3K8	S222	G217C	217	Missense	distal	-5	no	34.924	34.971	EPSD;PhosphoSitePlus	COSMIC	13.250	Up-regulation
STE_STE-Unique_MAP3K8_ST	P36507	MAP2K2	P41279	MAP3K8	S222	S222Y	222	Missense	central	0	yes	34.924	0.000	EPSD;PhosphoSitePlus	COSMIC	13.250	Loss
STE_STE-Unique_MAP3K8_ST	P36507	MAP2K2	P41279	MAP3K8	S222	M223V	223	Missense	proximal	1	no	34.924	33.866	EPSD;PhosphoSitePlus	COSMIC	13.250	Down-regulation
STE_STE-Unique_MAP3K8_ST	P36507	MAP2K2	P41279	MAP3K8	S222	V215E	215	Missense	distal	-7	no	34.924	34.501	EPSD;PhosphoSitePlus	COSMIC	13.250	Down-regulation
STE_STE-Unique_MAP3K8_ST	P36507	MAP2K2	P41279	MAP3K8	S226	R231H	231	Missense	distal	5	no	29.977	30.608	PhosphoSitePlus;EPSD	COSMIC	13.250	Up-regulation
STE_STE-Unique_MAP3K8_ST	P36507	MAP2K2	P41279	MAP3K8	S226	S222Y	222	Missense	distal	-4	no	29.977	30.729	PhosphoSitePlus;EPSD	COSMIC	13.250	Up-regulation
STE_STE-Unique_MAP3K8_ST	P36507	MAP2K2	P41279	MAP3K8	S226	M223V	223	Missense	distal	-3	no	29.977	28.303	PhosphoSitePlus;EPSD	COSMIC	13.250	Down-regulation
STE_STE-Unique_MAP3K8_ST	P36507	MAP2K2	P41279	MAP3K8	S312	G309R	309	Missense	distal	-3	no	1.048	13.942	EPSD	COSMIC	13.250	Gain
STE_STE-Unique_MAP3K8_ST	O14757	CHEK1	P41279	MAP3K8	T153	N159I	159	Missense	distal	6	no	14.179	12.980	EPSD	COSMIC	13.250	Loss
STE_STE-Unique_MAP3K8_ST	O14757	CHEK1	P41279	MAP3K8	S301	F300L	300	Missense	proximal	-1	no	14.872	14.148	EPSD	COSMIC	13.250	Down-regulation
STE_STE-Unique_MAP3K8_ST	O14757	CHEK1	P41279	MAP3K8	S301	P302A	302	Missense	proximal	1	no	14.872	12.085	EPSD	COSMIC	13.250	Loss
STE_STE-Unique_MAP3K8_ST	O14757	CHEK1	P41279	MAP3K8	S301	S308I	308	Missense	distal	7	no	14.872	14.259	EPSD	COSMIC	13.250	Down-regulation
STE_STE-Unique_MAP3K8_ST	O14757	CHEK1	P41279	MAP3K8	S301	S307F	307	Missense	distal	6	no	14.872	14.592	EPSD	COSMIC	13.250	Down-regulation
STE_STE-Unique_MAP3K8_ST	O14757	CHEK1	P41279	MAP3K8	S307	F300L	300	Missense	distal	-7	no	18.590	18.550	EPSD	COSMIC	13.250	Down-regulation
STE_STE-Unique_MAP3K8_ST	O14757	CHEK1	P41279	MAP3K8	S307	P302A	302	Missense	distal	-5	no	18.590	18.547	EPSD	COSMIC	13.250	Down-regulation
STE_STE-Unique_MAP3K8_ST	O14757	CHEK1	P41279	MAP3K8	S307	V312M	312	Missense	distal	5	no	18.590	18.441	EPSD	COSMIC;CCLE	13.250	Down-regulation
STE_STE-Unique_MAP3K8_ST	O14757	CHEK1	P41279	MAP3K8	S307	S308I	308	Missense	proximal	1	no	18.590	20.220	EPSD	COSMIC	13.250	Up-regulation
STE_STE-Unique_MAP3K8_ST	O14757	CHEK1	P41279	MAP3K8	S307	S307F	307	Missense	central	0	yes	18.590	0.000	EPSD	COSMIC	13.250	Loss
STE_STE-Unique_MAP3K8_ST	O14757	CHEK1	P41279	MAP3K8	T330	S326F	326	Missense	distal	-4	no	14.654	15.629	EPSD	COSMIC	13.250	Up-regulation
STE_STE-Unique_MAP3K8_ST	O14757	CHEK1	P41279	MAP3K8	T330	P332L	332	Missense	proximal	2	no	14.654	14.754	EPSD	COSMIC	13.250	Up-regulation
STE_STE-Unique_MAP3K8_ST	O14757	CHEK1	P41279	MAP3K8	S331	P332L	332	Missense	proximal	1	no	11.321	14.330	EPSD	COSMIC	13.250	Gain
STE_STE-Unique_MAP3K8_ST	O14757	CHEK1	P41279	MAP3K8	S345	G341R	341	Missense	distal	-4	no	22.388	22.428	PhosphoSitePlus	COSMIC	13.250	Up-regulation
STE_STE-Unique_MAP3K8_ST	O14757	CHEK1	P41279	MAP3K8	S345	F344L	344	Missense	proximal	-1	no	22.388	21.664	PhosphoSitePlus	COSMIC	13.250	Down-regulation
STE_STE-Unique_MAP3K8_ST	O14757	CHEK1	P41279	MAP3K8	S345	H352Y	352	Missense	distal	7	no	22.388	22.447	PhosphoSitePlus	COSMIC	13.250	Up-regulation
STE_STE-Unique_MAP3K8_ST	O14757	CHEK1	P41279	MAP3K8	T362	G361D	361	Missense	proximal	-1	no	10.724	13.436	EPSD	COSMIC;GDSC;CCLE	13.250	Gain
STE_STE-Unique_MAP3K8_ST	O14757	CHEK1	P41279	MAP3K8	T417	L424P	424	Missense	distal	7	no	13.786	14.057	EPSD	COSMIC	13.250	Up-regulation
STE_STE-Unique_MAP3K8_ST	O14757	CHEK1	P41279	MAP3K8	T417	V412A	412	Missense	distal	-5	no	13.786	13.721	EPSD	COSMIC	13.250	Down-regulation
STE_STE-Unique_MAP3K8_ST	P06748	NPM1	P41279	MAP3K8	S195	P200S	200	Missense	distal	5	no	31.018	30.866	EPSD	COSMIC	13.250	Down-regulation
STE_STE-Unique_MAP3K8_ST	P06748	NPM1	P41279	MAP3K8	S195	S195F	195	Missense	central	0	yes	31.018	0.000	EPSD	COSMIC	13.250	Loss
STE_STE-Unique_MAP3K8_ST	P06748	NPM1	P41279	MAP3K8	T199	P200S	200	Missense	proximal	1	no	36.589	33.857	PhosphoSitePlus	COSMIC	13.250	Down-regulation
STE_STE-Unique_MAP3K8_ST	P06748	NPM1	P41279	MAP3K8	T199	S195F	195	Missense	distal	-4	no	36.589	37.564	PhosphoSitePlus	COSMIC	13.250	Up-regulation
STE_STE-Unique_MAP3K8_ST	P06748	NPM1	P41279	MAP3K8	S207	P200S	200	Missense	distal	-7	no	13.108	13.308	EPSD	COSMIC	13.250	Gain
STE_STE-Unique_MAP3K8_ST	P06748	NPM1	P41279	MAP3K8	S218	G224R	224	Missense	distal	6	no	12.826	14.222	EPSD	COSMIC	13.250	Gain
STE_STE-Unique_MAP3K8_ST	P06748	NPM1	P41279	MAP3K8	S227	G224R	224	Missense	distal	-3	no	7.292	20.186	EPSD	COSMIC	13.250	Gain
STE_STE-Unique_MAP3K8_ST	P06748	NPM1	P41279	MAP3K8	S293	W290L	290	Missense	distal	-3	no	10.821	15.449	EPSD	COSMIC	13.250	Gain
CMGC_MAPK_JNK_MAPK9_ST	P46937	YAP1	P45984	MAPK9	S61	E62D	62	Missense	proximal	1	no	137.525	143.011	EPSD	COSMIC	140.458	Gain
CMGC_MAPK_JNK_MAPK9_ST	P46937	YAP1	P45984	MAPK9	T77	V72G	72	Missense	distal	-5	no	142.599	142.594	EPSD	COSMIC	140.458	Down-regulation
CMGC_MAPK_JNK_MAPK9_ST	P46937	YAP1	P45984	MAPK9	T77	M73I	73	Missense	distal	-4	no	142.599	140.862	EPSD	COSMIC	140.458	Down-regulation
CMGC_MAPK_JNK_MAPK9_ST	P46937	YAP1	P45984	MAPK9	T110	R106G	106	Missense	distal	-4	no	143.596	142.361	EPSD	COSMIC	140.458	Down-regulation
CMGC_MAPK_JNK_MAPK9_ST	P46937	YAP1	P45984	MAPK9	T110	S105P	105	Missense	distal	-5	no	143.596	143.615	EPSD	COSMIC	140.458	Up-regulation
CMGC_MAPK_JNK_MAPK9_ST	P46937	YAP1	P45984	MAPK9	T119	A125G	125	Missense	distal	6	no	163.538	163.226	EPSD;PhosphoSitePlus	COSMIC	140.458	Down-regulation
CMGC_MAPK_JNK_MAPK9_ST	P46937	YAP1	P45984	MAPK9	S128	L132R	132	Missense	distal	4	no	154.316	153.929	EPSD	COSMIC	140.458	Down-regulation
CMGC_MAPK_JNK_MAPK9_ST	P46937	YAP1	P45984	MAPK9	S128	Q133H	133	Missense	distal	5	no	154.316	154.857	EPSD	COSMIC	140.458	Up-regulation
CMGC_MAPK_JNK_MAPK9_ST	P46937	YAP1	P45984	MAPK9	S128	S127F	127	Missense	proximal	-1	no	154.316	153.941	EPSD	COSMIC	140.458	Down-regulation
CMGC_MAPK_JNK_MAPK9_ST	P46937	YAP1	P45984	MAPK9	S128	A125G	125	Missense	distal	-3	no	154.316	152.637	EPSD	COSMIC	140.458	Down-regulation
CMGC_MAPK_JNK_MAPK9_ST	P46937	YAP1	P45984	MAPK9	S138	L132R	132	Missense	distal	-6	no	156.939	157.492	EPSD;PhosphoSitePlus	COSMIC	140.458	Up-regulation
CMGC_MAPK_JNK_MAPK9_ST	P46937	YAP1	P45984	MAPK9	S138	G140W	140	Missense	proximal	2	no	156.939	157.088	EPSD;PhosphoSitePlus	COSMIC	140.458	Up-regulation
CMGC_MAPK_JNK_MAPK9_ST	P46937	YAP1	P45984	MAPK9	S138	T145S	145	Missense	distal	7	no	156.939	156.645	EPSD;PhosphoSitePlus	COSMIC	140.458	Down-regulation
CMGC_MAPK_JNK_MAPK9_ST	P46937	YAP1	P45984	MAPK9	S138	P139F	139	Missense	proximal	1	no	156.939	-115.066	EPSD;PhosphoSitePlus	COSMIC	140.458	Loss
CMGC_MAPK_JNK_MAPK9_ST	P46937	YAP1	P45984	MAPK9	S138	Q133H	133	Missense	distal	-5	no	156.939	157.011	EPSD;PhosphoSitePlus	COSMIC	140.458	Up-regulation
CMGC_MAPK_JNK_MAPK9_ST	P46937	YAP1	P45984	MAPK9	T143	G140W	140	Missense	distal	-3	no	158.240	156.356	EPSD	COSMIC	140.458	Down-regulation
CMGC_MAPK_JNK_MAPK9_ST	P46937	YAP1	P45984	MAPK9	T143	T145S	145	Missense	proximal	2	no	158.240	158.159	EPSD	COSMIC	140.458	Down-regulation
CMGC_MAPK_JNK_MAPK9_ST	P46937	YAP1	P45984	MAPK9	T143	P139F	139	Missense	distal	-4	no	158.240	155.136	EPSD	COSMIC	140.458	Down-regulation
CMGC_MAPK_JNK_MAPK9_ST	P46937	YAP1	P45984	MAPK9	T154	A152T	152	Missense	proximal	-2	no	159.726	157.360	PhosphoSitePlus;EPSD	COSMIC	140.458	Down-regulation
CMGC_MAPK_JNK_MAPK9_ST	P46937	YAP1	P45984	MAPK9	T154	P151A	151	Missense	distal	-3	no	159.726	159.101	PhosphoSitePlus;EPSD	COSMIC	140.458	Down-regulation
CMGC_MAPK_JNK_MAPK9_ST	P46937	YAP1	P45984	MAPK9	T154	L160H	160	Missense	distal	6	no	159.726	159.731	PhosphoSitePlus;EPSD	COSMIC	140.458	Up-regulation
CMGC_MAPK_JNK_MAPK9_ST	P46937	YAP1	P45984	MAPK9	S217	V212I	212	Missense	distal	-5	no	152.671	152.694	EPSD	COSMIC	140.458	Up-regulation
CMGC_MAPK_JNK_MAPK9_ST	P46937	YAP1	P45984	MAPK9	S217	M210I	210	Missense	distal	-7	no	152.671	151.443	EPSD	COSMIC	140.458	Down-regulation
CMGC_MAPK_JNK_MAPK9_ST	P46937	YAP1	P45984	MAPK9	S227	S227L	227	Missense	central	0	yes	147.497	0.000	EPSD	COSMIC;GDSC	140.458	Loss
CMGC_MAPK_JNK_MAPK9_ST	P46937	YAP1	P45984	MAPK9	S227	M225I	225	Missense	proximal	-2	no	147.497	146.229	EPSD	COSMIC	140.458	Down-regulation
CMGC_MAPK_JNK_MAPK9_ST	P46937	YAP1	P45984	MAPK9	S227	P233S	233	Missense	distal	6	no	147.497	147.524	EPSD	COSMIC	140.458	Up-regulation
CMGC_MAPK_JNK_MAPK9_ST	P46937	YAP1	P45984	MAPK9	S227	L232F	232	Missense	distal	5	no	147.497	147.975	EPSD	COSMIC;GDSC;CCLE	140.458	Up-regulation
CMGC_MAPK_JNK_MAPK9_ST	P46937	YAP1	P45984	MAPK9	S227	D234H	234	Missense	distal	7	no	147.497	147.130	EPSD	COSMIC	140.458	Down-regulation
CMGC_MAPK_JNK_MAPK9_ST	P46937	YAP1	P45984	MAPK9	S227	P231S	231	Missense	distal	4	no	147.497	147.599	EPSD	COSMIC	140.458	Up-regulation
CMGC_MAPK_JNK_MAPK9_ST	P46937	YAP1	P45984	MAPK9	S289	P284L	284	Missense	distal	-5	no	160.914	161.013	EPSD	COSMIC	140.458	Up-regulation
CMGC_MAPK_JNK_MAPK9_ST	P46937	YAP1	P45984	MAPK9	S336	A338T	338	Missense	proximal	2	no	143.713	143.879	EPSD	COSMIC	140.458	Up-regulation
CMGC_MAPK_JNK_MAPK9_ST	P46937	YAP1	P45984	MAPK9	S336	M330I	330	Missense	distal	-6	no	143.713	143.285	EPSD	COSMIC;GDSC	140.458	Down-regulation
CMGC_MAPK_JNK_MAPK9_ST	P46937	YAP1	P45984	MAPK9	S336	S340A	340	Missense	distal	4	no	143.713	143.639	EPSD	COSMIC;GDSC	140.458	Down-regulation
CMGC_MAPK_JNK_MAPK9_ST	P46937	YAP1	P45984	MAPK9	S340	A338T	338	Missense	proximal	-2	no	159.000	156.634	EPSD	COSMIC	140.458	Down-regulation
CMGC_MAPK_JNK_MAPK9_ST	P46937	YAP1	P45984	MAPK9	S340	S340A	340	Missense	central	0	yes	159.000	0.000	EPSD	COSMIC;GDSC	140.458	Loss
CMGC_MAPK_JNK_MAPK9_ST	P46937	YAP1	P45984	MAPK9	S367	S371F	371	Missense	distal	4	no	157.971	158.477	EPSD	COSMIC	140.458	Up-regulation
CMGC_MAPK_JNK_MAPK9_ST	P46937	YAP1	P45984	MAPK9	S367	S367F	367	Missense	central	0	yes	157.971	0.000	EPSD	COSMIC	140.458	Loss
CMGC_MAPK_JNK_MAPK9_ST	P46937	YAP1	P45984	MAPK9	T378	T376P	376	Missense	proximal	-2	no	138.015	141.651	EPSD	COSMIC	140.458	Gain
CMGC_MAPK_JNK_MAPK9_ST	P46937	YAP1	P45984	MAPK9	T379	N380T	380	Missense	proximal	1	no	-36.816	144.357	EPSD	COSMIC	140.458	Gain
CMGC_MAPK_JNK_MAPK9_ST	P46937	YAP1	P45984	MAPK9	S382	N380T	380	Missense	proximal	-2	no	141.944	140.956	EPSD	COSMIC	140.458	Down-regulation
CMGC_MAPK_JNK_MAPK9_ST	P46937	YAP1	P45984	MAPK9	S382	S382C	382	Missense	central	0	yes	141.944	0.000	EPSD	COSMIC	140.458	Loss
CMGC_MAPK_JNK_MAPK9_ST	P46937	YAP1	P45984	MAPK9	S382	L386P	386	Missense	distal	4	no	141.944	141.568	EPSD	COSMIC	140.458	Down-regulation
CMGC_MAPK_JNK_MAPK9_ST	P46937	YAP1	P45984	MAPK9	S382	D383H	383	Missense	proximal	1	no	141.944	-2.756	EPSD	COSMIC	140.458	Loss
CMGC_MAPK_JNK_MAPK9_ST	P46937	YAP1	P45984	MAPK9	S382	T378I	378	Missense	distal	-4	no	141.944	142.154	EPSD	COSMIC	140.458	Up-regulation
CMGC_MAPK_JNK_MAPK9_ST	P46937	YAP1	P45984	MAPK9	S382	D383G	383	Missense	proximal	1	no	141.944	-18.539	EPSD	COSMIC	140.458	Loss
CMGC_MAPK_JNK_MAPK9_ST	P46937	YAP1	P45984	MAPK9	S382	F385L	385	Missense	distal	3	no	141.944	142.036	EPSD	COSMIC	140.458	Up-regulation
CMGC_MAPK_JNK_MAPK9_ST	P46937	YAP1	P45984	MAPK9	S382	T376A	376	Missense	distal	-6	no	141.944	142.299	EPSD	COSMIC	140.458	Up-regulation
CMGC_MAPK_JNK_MAPK9_ST	P46937	YAP1	P45984	MAPK9	S382	T376P	376	Missense	distal	-6	no	141.944	142.304	EPSD	COSMIC	140.458	Up-regulation
CMGC_MAPK_JNK_MAPK9_ST	P46937	YAP1	P45984	MAPK9	S382	T378M	378	Missense	distal	-4	no	141.944	143.891	EPSD	COSMIC	140.458	Up-regulation
CMGC_MAPK_JNK_MAPK9_ST	P46937	YAP1	P45984	MAPK9	S382	M377V	377	Missense	distal	-5	no	141.944	142.031	EPSD	COSMIC	140.458	Up-regulation
CMGC_MAPK_JNK_MAPK9_ST	P46937	YAP1	P45984	MAPK9	S382	M377I	377	Missense	distal	-5	no	141.944	142.054	EPSD	COSMIC;GDSC;CCLE	140.458	Up-regulation
CMGC_MAPK_JNK_MAPK9_ST	P46937	YAP1	P45984	MAPK9	T412	N418T	418	Missense	distal	6	no	159.478	158.899	EPSD	COSMIC	140.458	Down-regulation
CMGC_MAPK_JNK_MAPK9_ST	P46937	YAP1	P45984	MAPK9	T412	F416L	416	Missense	distal	4	no	159.478	159.247	EPSD	COSMIC	140.458	Down-regulation
CMGC_MAPK_JNK_MAPK9_ST	P46937	YAP1	P45984	MAPK9	T412	R411Q	411	Missense	proximal	-1	no	159.478	159.429	EPSD	COSMIC	140.458	Down-regulation
CMGC_MAPK_JNK_MAPK9_ST	O43602	DCX	P45984	MAPK9	S28	R22W	22	Missense	distal	-6	no	157.902	157.097	EPSD	COSMIC	140.458	Down-regulation
CMGC_MAPK_JNK_MAPK9_ST	O43602	DCX	P45984	MAPK9	S28	P27T	27	Missense	proximal	-1	no	157.902	157.612	EPSD	COSMIC	140.458	Down-regulation
CMGC_MAPK_JNK_MAPK9_ST	O43602	DCX	P45984	MAPK9	S28	S28I	28	Missense	central	0	yes	157.902	0.000	EPSD	COSMIC	140.458	Loss
CMGC_MAPK_JNK_MAPK9_ST	O43602	DCX	P45984	MAPK9	S28	R22Q	22	Missense	distal	-6	no	157.902	157.831	EPSD	COSMIC	140.458	Down-regulation
CMGC_MAPK_JNK_MAPK9_ST	O43602	DCX	P45984	MAPK9	S28	A33T	33	Missense	distal	5	no	157.902	158.281	EPSD	COSMIC	140.458	Up-regulation
CMGC_MAPK_JNK_MAPK9_ST	O43602	DCX	P45984	MAPK9	S28	M23I	23	Missense	distal	-5	no	157.902	158.012	EPSD	COSMIC	140.458	Up-regulation
CMGC_MAPK_JNK_MAPK9_ST	O43602	DCX	P45984	MAPK9	S28	R22L	22	Missense	distal	-6	no	157.902	157.348	EPSD	COSMIC	140.458	Down-regulation
CMGC_MAPK_JNK_MAPK9_ST	O43602	DCX	P45984	MAPK9	S28	T30N	30	Missense	proximal	2	no	157.902	157.732	EPSD	COSMIC	140.458	Down-regulation
CMGC_MAPK_JNK_MAPK9_ST	O43602	DCX	P45984	MAPK9	S28	H34Q	34	Missense	distal	6	no	157.902	158.361	EPSD	COSMIC	140.458	Up-regulation
CMGC_MAPK_JNK_MAPK9_ST	O43602	DCX	P45984	MAPK9	S28	S32C	32	Missense	distal	4	no	157.902	158.046	EPSD	COSMIC	140.458	Up-regulation
CMGC_MAPK_JNK_MAPK9_ST	O43602	DCX	P45984	MAPK9	S32	R39Q	39	Missense	distal	7	no	141.959	142.202	EPSD	COSMIC	140.458	Up-regulation
CMGC_MAPK_JNK_MAPK9_ST	O43602	DCX	P45984	MAPK9	S32	P27T	27	Missense	distal	-5	no	141.959	141.985	EPSD	COSMIC	140.458	Up-regulation
CMGC_MAPK_JNK_MAPK9_ST	O43602	DCX	P45984	MAPK9	S32	S28I	28	Missense	distal	-4	no	141.959	140.098	EPSD	COSMIC	140.458	Loss
CMGC_MAPK_JNK_MAPK9_ST	O43602	DCX	P45984	MAPK9	S32	R39G	39	Missense	distal	7	no	141.959	142.708	EPSD	COSMIC	140.458	Up-regulation
CMGC_MAPK_JNK_MAPK9_ST	O43602	DCX	P45984	MAPK9	S32	A33T	33	Missense	proximal	1	no	141.959	141.407	EPSD	COSMIC	140.458	Down-regulation
CMGC_MAPK_JNK_MAPK9_ST	O43602	DCX	P45984	MAPK9	S32	T30N	30	Missense	proximal	-2	no	141.959	142.947	EPSD	COSMIC	140.458	Up-regulation
CMGC_MAPK_JNK_MAPK9_ST	O43602	DCX	P45984	MAPK9	S32	H34Q	34	Missense	proximal	2	no	141.959	141.821	EPSD	COSMIC	140.458	Down-regulation
CMGC_MAPK_JNK_MAPK9_ST	O43602	DCX	P45984	MAPK9	S32	S32C	32	Missense	central	0	yes	141.959	0.000	EPSD	COSMIC	140.458	Loss
CMGC_MAPK_JNK_MAPK9_ST	O43602	DCX	P45984	MAPK9	T203	R196H	196	Missense	distal	-7	no	142.330	140.585	EPSD	COSMIC	140.458	Down-regulation
CMGC_MAPK_JNK_MAPK9_ST	O43602	DCX	P45984	MAPK9	T203	S206T	206	Missense	distal	3	no	142.330	142.216	EPSD	COSMIC;CCLE	140.458	Down-regulation
CMGC_MAPK_JNK_MAPK9_ST	O43602	DCX	P45984	MAPK9	T203	H205N	205	Missense	proximal	2	no	142.330	142.179	EPSD	COSMIC	140.458	Down-regulation
CMGC_MAPK_JNK_MAPK9_ST	O43602	DCX	P45984	MAPK9	T203	F207C	207	Missense	distal	4	no	142.330	141.969	EPSD	COSMIC	140.458	Down-regulation
CMGC_MAPK_JNK_MAPK9_ST	O43602	DCX	P45984	MAPK9	T203	E208Q	208	Missense	distal	5	no	142.330	142.283	EPSD	COSMIC	140.458	Down-regulation
CMGC_MAPK_JNK_MAPK9_ST	O43602	DCX	P45984	MAPK9	S287	S287F	287	Missense	central	0	yes	155.605	0.000	EPSD	COSMIC	140.458	Loss
CMGC_MAPK_JNK_MAPK9_ST	O43602	DCX	P45984	MAPK9	S287	P288L	288	Missense	proximal	1	no	155.605	110.702	EPSD	COSMIC	140.458	Loss
CMGC_MAPK_JNK_MAPK9_ST	O43602	DCX	P45984	MAPK9	S287	P290L	290	Missense	distal	3	no	155.605	155.296	EPSD	COSMIC	140.458	Down-regulation
CMGC_MAPK_JNK_MAPK9_ST	O43602	DCX	P45984	MAPK9	S287	P288A	288	Missense	proximal	1	no	155.605	136.961	EPSD	COSMIC	140.458	Loss
CMGC_MAPK_JNK_MAPK9_ST	O43602	DCX	P45984	MAPK9	S287	P290H	290	Missense	distal	3	no	155.605	155.443	EPSD	COSMIC	140.458	Down-regulation
CMGC_MAPK_JNK_MAPK9_ST	O43602	DCX	P45984	MAPK9	T289	S287F	287	Missense	proximal	-2	no	157.792	155.522	EPSD	COSMIC	140.458	Down-regulation
CMGC_MAPK_JNK_MAPK9_ST	O43602	DCX	P45984	MAPK9	T289	P288L	288	Missense	proximal	-1	no	157.792	157.636	EPSD	COSMIC	140.458	Down-regulation
CMGC_MAPK_JNK_MAPK9_ST	O43602	DCX	P45984	MAPK9	T289	P290L	290	Missense	proximal	1	no	157.792	112.889	EPSD	COSMIC	140.458	Loss
CMGC_MAPK_JNK_MAPK9_ST	O43602	DCX	P45984	MAPK9	T289	P288A	288	Missense	proximal	-1	no	157.792	157.762	EPSD	COSMIC	140.458	Down-regulation
CMGC_MAPK_JNK_MAPK9_ST	O43602	DCX	P45984	MAPK9	T289	P290H	290	Missense	proximal	1	no	157.792	-2.314	EPSD	COSMIC	140.458	Loss
CMGC_MAPK_JNK_MAPK9_ST	O43602	DCX	P45984	MAPK9	S297	S297N	297	Missense	central	0	yes	161.160	0.000	EPSD	COSMIC	140.458	Loss
CMGC_MAPK_JNK_MAPK9_ST	O43602	DCX	P45984	MAPK9	S297	S297I	297	Missense	central	0	yes	161.160	0.000	EPSD	COSMIC	140.458	Loss
CMGC_MAPK_JNK_MAPK9_ST	O43602	DCX	P45984	MAPK9	S297	P290L	290	Missense	distal	-7	no	161.160	160.033	EPSD	COSMIC	140.458	Down-regulation
CMGC_MAPK_JNK_MAPK9_ST	O43602	DCX	P45984	MAPK9	S297	P300S	300	Missense	distal	3	no	161.160	161.113	EPSD	COSMIC	140.458	Down-regulation
CMGC_MAPK_JNK_MAPK9_ST	O43602	DCX	P45984	MAPK9	S297	R302H	302	Missense	distal	5	no	161.160	161.910	EPSD	COSMIC	140.458	Up-regulation
CMGC_MAPK_JNK_MAPK9_ST	O43602	DCX	P45984	MAPK9	S297	R303Q	303	Missense	distal	6	no	161.160	161.328	EPSD	COSMIC	140.458	Up-regulation
CMGC_MAPK_JNK_MAPK9_ST	O43602	DCX	P45984	MAPK9	S297	P290H	290	Missense	distal	-7	no	161.160	161.026	EPSD	COSMIC	140.458	Down-regulation
CMGC_MAPK_JNK_MAPK9_ST	O43602	DCX	P45984	MAPK9	S306	S306F	306	Missense	central	0	yes	156.799	0.000	EPSD	COSMIC	140.458	Loss
CMGC_MAPK_JNK_MAPK9_ST	O43602	DCX	P45984	MAPK9	S306	G311D	311	Missense	distal	5	no	156.799	156.787	EPSD	COSMIC	140.458	Down-regulation
CMGC_MAPK_JNK_MAPK9_ST	O43602	DCX	P45984	MAPK9	S306	D313N	313	Missense	distal	7	no	156.799	156.080	EPSD	COSMIC	140.458	Down-regulation
CMGC_MAPK_JNK_MAPK9_ST	O43602	DCX	P45984	MAPK9	S306	P300S	300	Missense	distal	-6	no	156.799	156.707	EPSD	COSMIC	140.458	Down-regulation
CMGC_MAPK_JNK_MAPK9_ST	O43602	DCX	P45984	MAPK9	S306	G299V	299	Missense	distal	-7	no	156.799	156.204	EPSD	COSMIC	140.458	Down-regulation
CMGC_MAPK_JNK_MAPK9_ST	O43602	DCX	P45984	MAPK9	S306	N312D	312	Missense	distal	6	no	156.799	156.333	EPSD	COSMIC	140.458	Down-regulation
CMGC_MAPK_JNK_MAPK9_ST	O43602	DCX	P45984	MAPK9	S306	R302H	302	Missense	distal	-4	no	156.799	155.159	EPSD	COSMIC	140.458	Down-regulation
CMGC_MAPK_JNK_MAPK9_ST	O43602	DCX	P45984	MAPK9	S306	G311S	311	Missense	distal	5	no	156.799	156.222	EPSD	COSMIC	140.458	Down-regulation
CMGC_MAPK_JNK_MAPK9_ST	O43602	DCX	P45984	MAPK9	S306	N312K	312	Missense	distal	6	no	156.799	156.455	EPSD	COSMIC	140.458	Down-regulation
CMGC_MAPK_JNK_MAPK9_ST	O43602	DCX	P45984	MAPK9	S306	G311V	311	Missense	distal	5	no	156.799	156.651	EPSD	COSMIC	140.458	Down-regulation
CMGC_MAPK_JNK_MAPK9_ST	O43602	DCX	P45984	MAPK9	S306	G311C	311	Missense	distal	5	no	156.799	156.610	EPSD	COSMIC	140.458	Down-regulation
CMGC_MAPK_JNK_MAPK9_ST	O43602	DCX	P45984	MAPK9	S306	D313G	313	Missense	distal	7	no	156.799	156.583	EPSD	COSMIC;CCLE	140.458	Down-regulation
CMGC_MAPK_JNK_MAPK9_ST	O43602	DCX	P45984	MAPK9	S306	R303Q	303	Missense	distal	-3	no	156.799	156.576	EPSD	COSMIC	140.458	Down-regulation
CMGC_MAPK_JNK_MAPK9_ST	O43602	DCX	P45984	MAPK9	S310	G311D	311	Missense	proximal	1	no	-14.949	145.535	EPSD	COSMIC	140.458	Gain
CMGC_MAPK_JNK_MAPK9_ST	O43602	DCX	P45984	MAPK9	T319	S320A	320	Missense	proximal	1	no	-117.623	144.528	EPSD	COSMIC	140.458	Gain
CMGC_MAPK_JNK_MAPK9_ST	O43602	DCX	P45984	MAPK9	S325	P327S	327	Missense	proximal	2	no	141.034	141.129	EPSD	COSMIC	140.458	Up-regulation
CMGC_MAPK_JNK_MAPK9_ST	O43602	DCX	P45984	MAPK9	S325	S320Y	320	Missense	distal	-5	no	141.034	141.183	EPSD	COSMIC	140.458	Up-regulation
CMGC_MAPK_JNK_MAPK9_ST	O43602	DCX	P45984	MAPK9	S325	S329F	329	Missense	distal	4	no	141.034	141.539	EPSD	COSMIC	140.458	Up-regulation
CMGC_MAPK_JNK_MAPK9_ST	O43602	DCX	P45984	MAPK9	S325	S320A	320	Missense	distal	-5	no	141.034	141.042	EPSD	COSMIC	140.458	Up-regulation
CMGC_MAPK_JNK_MAPK9_ST	O43602	DCX	P45984	MAPK9	S325	Q331H	331	Missense	distal	6	no	141.034	140.575	EPSD	COSMIC	140.458	Down-regulation
CMGC_MAPK_JNK_MAPK9_ST	O43602	DCX	P45984	MAPK9	S325	S320F	320	Missense	distal	-5	no	141.034	141.177	EPSD	COSMIC	140.458	Up-regulation
CMGC_MAPK_JNK_MAPK9_ST	O43602	DCX	P45984	MAPK9	S325	P327R	327	Missense	proximal	2	no	141.034	141.008	EPSD	COSMIC	140.458	Down-regulation
CMGC_MAPK_JNK_MAPK9_ST	O43602	DCX	P45984	MAPK9	T326	P327S	327	Missense	proximal	1	no	162.619	-118.175	EPSD	COSMIC	140.458	Loss
CMGC_MAPK_JNK_MAPK9_ST	O43602	DCX	P45984	MAPK9	T326	S320Y	320	Missense	distal	-6	no	162.619	161.940	EPSD	COSMIC	140.458	Down-regulation
CMGC_MAPK_JNK_MAPK9_ST	O43602	DCX	P45984	MAPK9	T326	S329F	329	Missense	distal	3	no	162.619	162.267	EPSD	COSMIC	140.458	Down-regulation
CMGC_MAPK_JNK_MAPK9_ST	O43602	DCX	P45984	MAPK9	T326	S320A	320	Missense	distal	-6	no	162.619	162.705	EPSD	COSMIC	140.458	Up-regulation
CMGC_MAPK_JNK_MAPK9_ST	O43602	DCX	P45984	MAPK9	T326	Q331H	331	Missense	distal	5	no	162.619	163.160	EPSD	COSMIC	140.458	Up-regulation
CMGC_MAPK_JNK_MAPK9_ST	O43602	DCX	P45984	MAPK9	T326	S320F	320	Missense	distal	-6	no	162.619	161.920	EPSD	COSMIC	140.458	Down-regulation
CMGC_MAPK_JNK_MAPK9_ST	O43602	DCX	P45984	MAPK9	T326	P327R	327	Missense	proximal	1	no	162.619	125.031	EPSD	COSMIC	140.458	Loss
CMGC_MAPK_JNK_MAPK9_ST	O43602	DCX	P45984	MAPK9	S332	P327S	327	Missense	distal	-5	no	155.717	155.698	EPSD	COSMIC	140.458	Down-regulation
CMGC_MAPK_JNK_MAPK9_ST	O43602	DCX	P45984	MAPK9	S332	S329F	329	Missense	distal	-3	no	155.717	152.432	EPSD	COSMIC	140.458	Down-regulation
CMGC_MAPK_JNK_MAPK9_ST	O43602	DCX	P45984	MAPK9	S332	T336M	336	Missense	distal	4	no	155.717	155.482	EPSD	COSMIC	140.458	Down-regulation
CMGC_MAPK_JNK_MAPK9_ST	O43602	DCX	P45984	MAPK9	S332	T338N	338	Missense	distal	6	no	155.717	156.297	EPSD	COSMIC	140.458	Up-regulation
CMGC_MAPK_JNK_MAPK9_ST	O43602	DCX	P45984	MAPK9	S332	Q331H	331	Missense	proximal	-1	no	155.717	155.498	EPSD	COSMIC	140.458	Down-regulation
CMGC_MAPK_JNK_MAPK9_ST	O43602	DCX	P45984	MAPK9	S332	P327R	327	Missense	distal	-5	no	155.717	155.710	EPSD	COSMIC	140.458	Down-regulation
CMGC_MAPK_JNK_MAPK9_ST	O43602	DCX	P45984	MAPK9	S335	P340S	340	Missense	distal	5	no	141.922	141.981	EPSD	COSMIC	140.458	Up-regulation
CMGC_MAPK_JNK_MAPK9_ST	O43602	DCX	P45984	MAPK9	S335	G341D	341	Missense	distal	6	no	141.922	141.936	EPSD	COSMIC	140.458	Up-regulation
CMGC_MAPK_JNK_MAPK9_ST	O43602	DCX	P45984	MAPK9	S335	S329F	329	Missense	distal	-6	no	141.922	141.224	EPSD	COSMIC	140.458	Down-regulation
CMGC_MAPK_JNK_MAPK9_ST	O43602	DCX	P45984	MAPK9	S335	P340T	340	Missense	distal	5	no	141.922	142.371	EPSD	COSMIC	140.458	Up-regulation
CMGC_MAPK_JNK_MAPK9_ST	O43602	DCX	P45984	MAPK9	S335	T336M	336	Missense	proximal	1	no	141.922	96.899	EPSD	COSMIC	140.458	Loss
CMGC_MAPK_JNK_MAPK9_ST	O43602	DCX	P45984	MAPK9	S335	T338N	338	Missense	distal	3	no	141.922	142.165	EPSD	COSMIC	140.458	Up-regulation
CMGC_MAPK_JNK_MAPK9_ST	O43602	DCX	P45984	MAPK9	S335	Q331H	331	Missense	distal	-4	no	141.922	138.852	EPSD	COSMIC	140.458	Loss
CMGC_MAPK_JNK_MAPK9_ST	O43602	DCX	P45984	MAPK9	T336	P340S	340	Missense	distal	4	no	165.407	165.509	EPSD	COSMIC	140.458	Up-regulation
CMGC_MAPK_JNK_MAPK9_ST	O43602	DCX	P45984	MAPK9	T336	G341D	341	Missense	distal	5	no	165.407	165.395	EPSD	COSMIC	140.458	Down-regulation
CMGC_MAPK_JNK_MAPK9_ST	O43602	DCX	P45984	MAPK9	T336	S329F	329	Missense	distal	-7	no	165.407	162.468	EPSD	COSMIC	140.458	Down-regulation
CMGC_MAPK_JNK_MAPK9_ST	O43602	DCX	P45984	MAPK9	T336	P340T	340	Missense	distal	4	no	165.407	165.607	EPSD	COSMIC	140.458	Up-regulation
CMGC_MAPK_JNK_MAPK9_ST	O43602	DCX	P45984	MAPK9	T336	T336M	336	Missense	central	0	yes	165.407	0.000	EPSD	COSMIC	140.458	Loss
CMGC_MAPK_JNK_MAPK9_ST	O43602	DCX	P45984	MAPK9	T336	T338N	338	Missense	proximal	2	no	165.407	165.237	EPSD	COSMIC	140.458	Down-regulation
CMGC_MAPK_JNK_MAPK9_ST	O43602	DCX	P45984	MAPK9	T336	Q331H	331	Missense	distal	-5	no	165.407	165.480	EPSD	COSMIC	140.458	Up-regulation
CMGC_MAPK_JNK_MAPK9_ST	O43602	DCX	P45984	MAPK9	S339	P340S	340	Missense	proximal	1	no	163.744	-117.050	EPSD	COSMIC	140.458	Loss
CMGC_MAPK_JNK_MAPK9_ST	O43602	DCX	P45984	MAPK9	S339	G341D	341	Missense	proximal	2	no	163.744	163.737	EPSD	COSMIC	140.458	Down-regulation
CMGC_MAPK_JNK_MAPK9_ST	O43602	DCX	P45984	MAPK9	S339	P340T	340	Missense	proximal	1	no	163.744	144.549	EPSD	COSMIC	140.458	Down-regulation
CMGC_MAPK_JNK_MAPK9_ST	O43602	DCX	P45984	MAPK9	S339	T336M	336	Missense	distal	-3	no	163.744	164.794	EPSD	COSMIC	140.458	Up-regulation
CMGC_MAPK_JNK_MAPK9_ST	O43602	DCX	P45984	MAPK9	S339	T338N	338	Missense	proximal	-1	no	163.744	164.092	EPSD	COSMIC	140.458	Up-regulation
CMGC_MAPK_JNK_MAPK9_ST	O43602	DCX	P45984	MAPK9	S339	R344W	344	Missense	distal	5	no	163.744	165.095	EPSD	COSMIC	140.458	Up-regulation
CMGC_MAPK_JNK_MAPK9_ST	O43602	DCX	P45984	MAPK9	S339	H346N	346	Missense	distal	7	no	163.744	163.393	EPSD	COSMIC	140.458	Down-regulation
CMGC_MAPK_JNK_MAPK9_ST	P10636	MAPT	P45984	MAPK9	S64	E62K	62	Missense	proximal	-2	no	144.805	142.737	EPSD	COSMIC	140.458	Down-regulation
CMGC_MAPK_JNK_MAPK9_ST	P10636	MAPT	P45984	MAPK9	S68	E62K	62	Missense	distal	-6	no	141.235	141.095	EPSD	COSMIC	140.458	Down-regulation
CMGC_MAPK_JNK_MAPK9_ST	P10636	MAPT	P45984	MAPK9	T69	E62K	62	Missense	distal	-7	no	157.136	156.685	EPSD	COSMIC	140.458	Down-regulation
CMGC_MAPK_JNK_MAPK9_ST	P10636	MAPT	P45984	MAPK9	T95	A89V	89	Missense	distal	-6	no	144.342	144.022	EPSD	COSMIC	140.458	Down-regulation
CMGC_MAPK_JNK_MAPK9_ST	P10636	MAPT	P45984	MAPK9	T102	I108V	108	Missense	distal	6	no	140.567	140.679	EPSD	COSMIC	140.458	Up-regulation
CMGC_MAPK_JNK_MAPK9_ST	P10636	MAPT	P45984	MAPK9	T102	G107R	107	Missense	distal	5	no	140.567	139.759	EPSD	COSMIC	140.458	Loss
CMGC_MAPK_JNK_MAPK9_ST	P10636	MAPT	P45984	MAPK9	T111	I108V	108	Missense	distal	-3	no	150.649	150.987	EPSD	COSMIC	140.458	Up-regulation
CMGC_MAPK_JNK_MAPK9_ST	P10636	MAPT	P45984	MAPK9	T111	G107R	107	Missense	distal	-4	no	150.649	151.884	EPSD	COSMIC	140.458	Up-regulation
CMGC_MAPK_JNK_MAPK9_ST	P10636	MAPT	P45984	MAPK9	S228	S227N	227	Missense	proximal	-1	no	156.450	156.620	EPSD	COSMIC	140.458	Up-regulation
CMGC_MAPK_JNK_MAPK9_ST	P10636	MAPT	P45984	MAPK9	S228	S227I	227	Missense	proximal	-1	no	156.450	156.325	EPSD	COSMIC	140.458	Down-regulation
CMGC_MAPK_JNK_MAPK9_ST	P10636	MAPT	P45984	MAPK9	S228	E226K	226	Missense	proximal	-2	no	156.450	154.381	EPSD	COSMIC	140.458	Down-regulation
CMGC_MAPK_JNK_MAPK9_ST	P10636	MAPT	P45984	MAPK9	S228	Q230R	230	Missense	proximal	2	no	156.450	156.405	EPSD	COSMIC	140.458	Down-regulation
CMGC_MAPK_JNK_MAPK9_ST	P10636	MAPT	P45984	MAPK9	S228	P233S	233	Missense	distal	5	no	156.450	156.508	EPSD	COSMIC	140.458	Up-regulation
CMGC_MAPK_JNK_MAPK9_ST	P10636	MAPT	P45984	MAPK9	S228	D225E	225	Missense	distal	-3	no	156.450	157.240	EPSD	COSMIC	140.458	Up-regulation
CMGC_MAPK_JNK_MAPK9_ST	P10636	MAPT	P45984	MAPK9	S228	S227G	227	Missense	proximal	-1	no	156.450	156.388	EPSD	COSMIC	140.458	Down-regulation
CMGC_MAPK_JNK_MAPK9_ST	P10636	MAPT	P45984	MAPK9	S228	S235L	235	Missense	distal	7	no	156.450	156.860	EPSD	COSMIC	140.458	Up-regulation
CMGC_MAPK_JNK_MAPK9_ST	P10636	MAPT	P45984	MAPK9	S232	S227N	227	Missense	distal	-5	no	154.055	154.031	EPSD	COSMIC	140.458	Down-regulation
CMGC_MAPK_JNK_MAPK9_ST	P10636	MAPT	P45984	MAPK9	S232	S227I	227	Missense	distal	-5	no	154.055	154.150	EPSD	COSMIC	140.458	Up-regulation
CMGC_MAPK_JNK_MAPK9_ST	P10636	MAPT	P45984	MAPK9	S232	A237T	237	Missense	distal	5	no	154.055	154.434	EPSD	COSMIC	140.458	Up-regulation
CMGC_MAPK_JNK_MAPK9_ST	P10636	MAPT	P45984	MAPK9	S232	E226K	226	Missense	distal	-6	no	154.055	153.914	EPSD	COSMIC	140.458	Down-regulation
CMGC_MAPK_JNK_MAPK9_ST	P10636	MAPT	P45984	MAPK9	S232	Q230R	230	Missense	proximal	-2	no	154.055	154.053	EPSD	COSMIC	140.458	Down-regulation
CMGC_MAPK_JNK_MAPK9_ST	P10636	MAPT	P45984	MAPK9	S232	S238P	238	Missense	distal	6	no	154.055	154.029	EPSD	COSMIC	140.458	Down-regulation
CMGC_MAPK_JNK_MAPK9_ST	P10636	MAPT	P45984	MAPK9	S232	P233S	233	Missense	proximal	1	no	154.055	-126.739	EPSD	COSMIC	140.458	Loss
CMGC_MAPK_JNK_MAPK9_ST	P10636	MAPT	P45984	MAPK9	S232	S238F	238	Missense	distal	6	no	154.055	153.505	EPSD	COSMIC	140.458	Down-regulation
CMGC_MAPK_JNK_MAPK9_ST	P10636	MAPT	P45984	MAPK9	S232	D225E	225	Missense	distal	-7	no	154.055	155.489	EPSD	COSMIC	140.458	Up-regulation
CMGC_MAPK_JNK_MAPK9_ST	P10636	MAPT	P45984	MAPK9	S232	S227G	227	Missense	distal	-5	no	154.055	154.123	EPSD	COSMIC	140.458	Up-regulation
CMGC_MAPK_JNK_MAPK9_ST	P10636	MAPT	P45984	MAPK9	S232	S235L	235	Missense	distal	3	no	154.055	153.795	EPSD	COSMIC	140.458	Down-regulation
CMGC_MAPK_JNK_MAPK9_ST	P10636	MAPT	P45984	MAPK9	S238	A237T	237	Missense	proximal	-1	no	155.330	155.070	EPSD	COSMIC	140.458	Down-regulation
CMGC_MAPK_JNK_MAPK9_ST	P10636	MAPT	P45984	MAPK9	S238	A240S	240	Missense	proximal	2	no	155.330	155.415	EPSD	COSMIC	140.458	Up-regulation
CMGC_MAPK_JNK_MAPK9_ST	P10636	MAPT	P45984	MAPK9	S238	D242N	242	Missense	distal	4	no	155.330	155.012	EPSD	COSMIC	140.458	Down-regulation
CMGC_MAPK_JNK_MAPK9_ST	P10636	MAPT	P45984	MAPK9	S238	R244W	244	Missense	distal	6	no	155.330	154.732	EPSD	COSMIC	140.458	Down-regulation
CMGC_MAPK_JNK_MAPK9_ST	P10636	MAPT	P45984	MAPK9	S238	S238P	238	Missense	central	0	yes	155.330	0.000	EPSD	COSMIC	140.458	Loss
CMGC_MAPK_JNK_MAPK9_ST	P10636	MAPT	P45984	MAPK9	S238	P233S	233	Missense	distal	-5	no	155.330	155.310	EPSD	COSMIC	140.458	Down-regulation
CMGC_MAPK_JNK_MAPK9_ST	P10636	MAPT	P45984	MAPK9	S238	S238F	238	Missense	central	0	yes	155.330	0.000	EPSD	COSMIC	140.458	Loss
CMGC_MAPK_JNK_MAPK9_ST	P10636	MAPT	P45984	MAPK9	S238	G243D	243	Missense	distal	5	no	155.330	155.318	EPSD	COSMIC	140.458	Down-regulation
CMGC_MAPK_JNK_MAPK9_ST	P10636	MAPT	P45984	MAPK9	S238	S235L	235	Missense	distal	-3	no	155.330	154.796	EPSD	COSMIC	140.458	Down-regulation
CMGC_MAPK_JNK_MAPK9_ST	P10636	MAPT	P45984	MAPK9	T248	A250T	250	Missense	proximal	2	no	146.145	146.311	EPSD	COSMIC	140.458	Up-regulation
CMGC_MAPK_JNK_MAPK9_ST	P10636	MAPT	P45984	MAPK9	T248	A250G	250	Missense	proximal	2	no	146.145	146.286	EPSD	COSMIC	140.458	Up-regulation
CMGC_MAPK_JNK_MAPK9_ST	P10636	MAPT	P45984	MAPK9	T248	D242N	242	Missense	distal	-6	no	146.145	146.658	EPSD	COSMIC	140.458	Up-regulation
CMGC_MAPK_JNK_MAPK9_ST	P10636	MAPT	P45984	MAPK9	T248	R244W	244	Missense	distal	-4	no	146.145	142.815	EPSD	COSMIC	140.458	Down-regulation
CMGC_MAPK_JNK_MAPK9_ST	P10636	MAPT	P45984	MAPK9	T248	G243D	243	Missense	distal	-5	no	146.145	146.171	EPSD	COSMIC	140.458	Up-regulation
CMGC_MAPK_JNK_MAPK9_ST	P10636	MAPT	P45984	MAPK9	S388	T386I	386	Missense	proximal	-2	no	140.062	140.562	EPSD	COSMIC	140.458	Gain
CMGC_MAPK_JNK_MAPK9_ST	P10636	MAPT	P45984	MAPK9	S411	L410F	410	Missense	proximal	-1	no	157.243	156.911	EPSD	COSMIC	140.458	Down-regulation
CMGC_MAPK_JNK_MAPK9_ST	P10636	MAPT	P45984	MAPK9	S411	P412S	412	Missense	proximal	1	no	157.243	-123.551	EPSD	COSMIC	140.458	Loss
CMGC_MAPK_JNK_MAPK9_ST	P10636	MAPT	P45984	MAPK9	T416	L410F	410	Missense	distal	-6	no	153.449	153.101	EPSD	COSMIC	140.458	Down-regulation
CMGC_MAPK_JNK_MAPK9_ST	P10636	MAPT	P45984	MAPK9	T416	P412S	412	Missense	distal	-4	no	153.449	153.628	EPSD	COSMIC	140.458	Up-regulation
CMGC_MAPK_JNK_MAPK9_ST	P10636	MAPT	P45984	MAPK9	S438	S443Y	443	Missense	distal	5	no	167.104	168.225	EPSD	COSMIC	140.458	Up-regulation
CMGC_MAPK_JNK_MAPK9_ST	P10636	MAPT	P45984	MAPK9	S447	R448Q	448	Missense	proximal	1	no	125.471	142.947	EPSD	COSMIC	140.458	Gain
CMGC_MAPK_JNK_MAPK9_ST	P10636	MAPT	P45984	MAPK9	T470	T466M	466	Missense	distal	-4	no	149.411	151.357	EPSD	COSMIC;GDSC;CCLE	140.458	Up-regulation
CMGC_MAPK_JNK_MAPK9_ST	P10636	MAPT	P45984	MAPK9	T470	K467T	467	Missense	distal	-3	no	149.411	149.659	EPSD	COSMIC	140.458	Up-regulation
CMGC_MAPK_JNK_MAPK9_ST	P10636	MAPT	P45984	MAPK9	T470	P477L	477	Missense	distal	7	no	149.411	150.050	EPSD	COSMIC	140.458	Up-regulation
CMGC_MAPK_JNK_MAPK9_ST	P10636	MAPT	P45984	MAPK9	T470	P477S	477	Missense	distal	7	no	149.411	149.639	EPSD	COSMIC	140.458	Up-regulation
CMGC_MAPK_JNK_MAPK9_ST	P10636	MAPT	P45984	MAPK9	T492	R487K	487	Missense	distal	-5	no	157.759	157.769	EPSD	COSMIC	140.458	Up-regulation
CMGC_MAPK_JNK_MAPK9_ST	P10636	MAPT	P45984	MAPK9	T492	K491R	491	Missense	proximal	-1	no	157.759	157.902	EPSD	COSMIC	140.458	Up-regulation
CMGC_MAPK_JNK_MAPK9_ST	P10636	MAPT	P45984	MAPK9	T492	R487G	487	Missense	distal	-5	no	157.759	157.815	EPSD	COSMIC	140.458	Up-regulation
CMGC_MAPK_JNK_MAPK9_ST	P10636	MAPT	P45984	MAPK9	T492	A495T	495	Missense	distal	3	no	157.759	157.548	EPSD	COSMIC	140.458	Down-regulation
CMGC_MAPK_JNK_MAPK9_ST	P10636	MAPT	P45984	MAPK9	T492	P493L	493	Missense	proximal	1	no	157.759	112.856	EPSD	COSMIC	140.458	Loss
CMGC_MAPK_JNK_MAPK9_ST	P10636	MAPT	P45984	MAPK9	T498	K491R	491	Missense	distal	-7	no	166.420	166.550	EPSD	COSMIC	140.458	Up-regulation
CMGC_MAPK_JNK_MAPK9_ST	P10636	MAPT	P45984	MAPK9	T498	A495T	495	Missense	distal	-3	no	166.420	165.172	EPSD	COSMIC	140.458	Down-regulation
CMGC_MAPK_JNK_MAPK9_ST	P10636	MAPT	P45984	MAPK9	T498	P493L	493	Missense	distal	-5	no	166.420	166.520	EPSD	COSMIC	140.458	Up-regulation
CMGC_MAPK_JNK_MAPK9_ST	P10636	MAPT	P45984	MAPK9	S516	G521V	521	Missense	distal	5	no	152.372	152.223	EPSD	COSMIC	140.458	Down-regulation
CMGC_MAPK_JNK_MAPK9_ST	P10636	MAPT	P45984	MAPK9	S516	G518V	518	Missense	proximal	2	no	152.372	152.371	EPSD	COSMIC	140.458	Down-regulation
CMGC_MAPK_JNK_MAPK9_ST	P10636	MAPT	P45984	MAPK9	S516	R511C	511	Missense	distal	-5	no	152.372	152.415	EPSD	COSMIC;CCLE	140.458	Up-regulation
CMGC_MAPK_JNK_MAPK9_ST	P10636	MAPT	P45984	MAPK9	S516	G509V	509	Missense	distal	-7	no	152.372	151.777	EPSD	COSMIC	140.458	Down-regulation
CMGC_MAPK_JNK_MAPK9_ST	P10636	MAPT	P45984	MAPK9	S519	G521V	521	Missense	proximal	2	no	159.830	159.829	EPSD	COSMIC	140.458	Down-regulation
CMGC_MAPK_JNK_MAPK9_ST	P10636	MAPT	P45984	MAPK9	S519	R526H	526	Missense	distal	7	no	159.830	160.427	EPSD	COSMIC	140.458	Up-regulation
CMGC_MAPK_JNK_MAPK9_ST	P10636	MAPT	P45984	MAPK9	S519	G518V	518	Missense	proximal	-1	no	159.830	159.746	EPSD	COSMIC	140.458	Down-regulation
CMGC_MAPK_JNK_MAPK9_ST	P10636	MAPT	P45984	MAPK9	T522	G521V	521	Missense	proximal	-1	no	159.360	159.277	EPSD	COSMIC	140.458	Down-regulation
CMGC_MAPK_JNK_MAPK9_ST	P10636	MAPT	P45984	MAPK9	T522	R526H	526	Missense	distal	4	no	159.360	159.641	EPSD	COSMIC	140.458	Up-regulation
CMGC_MAPK_JNK_MAPK9_ST	P10636	MAPT	P45984	MAPK9	T522	G518V	518	Missense	distal	-4	no	159.360	159.793	EPSD	COSMIC	140.458	Up-regulation
CMGC_MAPK_JNK_MAPK9_ST	P10636	MAPT	P45984	MAPK9	T522	R528S	528	Missense	distal	6	no	159.360	159.323	EPSD	COSMIC	140.458	Down-regulation
CMGC_MAPK_JNK_MAPK9_ST	P10636	MAPT	P45984	MAPK9	T529	R526H	526	Missense	distal	-3	no	158.082	155.696	EPSD	COSMIC	140.458	Down-regulation
CMGC_MAPK_JNK_MAPK9_ST	P10636	MAPT	P45984	MAPK9	T529	R528S	528	Missense	proximal	-1	no	158.082	157.946	EPSD	COSMIC	140.458	Down-regulation
CMGC_MAPK_JNK_MAPK9_ST	P10636	MAPT	P45984	MAPK9	T529	P530S	530	Missense	proximal	1	no	158.082	-122.712	EPSD	COSMIC	140.458	Loss
CMGC_MAPK_JNK_MAPK9_ST	P10636	MAPT	P45984	MAPK9	T529	P536H	536	Missense	distal	7	no	158.082	158.485	EPSD	COSMIC	140.458	Up-regulation
CMGC_MAPK_JNK_MAPK9_ST	P10636	MAPT	P45984	MAPK9	T529	P535Q	535	Missense	distal	6	no	158.082	158.314	EPSD	COSMIC	140.458	Up-regulation
CMGC_MAPK_JNK_MAPK9_ST	P10636	MAPT	P45984	MAPK9	T534	R528S	528	Missense	distal	-6	no	159.574	159.371	EPSD	COSMIC	140.458	Down-regulation
CMGC_MAPK_JNK_MAPK9_ST	P10636	MAPT	P45984	MAPK9	T534	P530S	530	Missense	distal	-4	no	159.574	159.753	EPSD	COSMIC	140.458	Up-regulation
CMGC_MAPK_JNK_MAPK9_ST	P10636	MAPT	P45984	MAPK9	T534	P536H	536	Missense	proximal	2	no	159.574	159.731	EPSD	COSMIC	140.458	Up-regulation
CMGC_MAPK_JNK_MAPK9_ST	P10636	MAPT	P45984	MAPK9	T534	P535Q	535	Missense	proximal	1	no	159.574	139.462	EPSD	COSMIC	140.458	Loss
CMGC_MAPK_JNK_MAPK9_ST	P10636	MAPT	P45984	MAPK9	T534	E539Q	539	Missense	distal	5	no	159.574	159.527	EPSD	COSMIC	140.458	Down-regulation
CMGC_MAPK_JNK_MAPK9_ST	P10636	MAPT	P45984	MAPK9	T548	P550S	550	Missense	proximal	2	no	157.366	157.462	EPSD	COSMIC	140.458	Up-regulation
CMGC_MAPK_JNK_MAPK9_ST	P10636	MAPT	P45984	MAPK9	T548	P553R	553	Missense	distal	5	no	157.366	157.193	EPSD	COSMIC	140.458	Down-regulation
CMGC_MAPK_JNK_MAPK9_ST	P10636	MAPT	P45984	MAPK9	T548	P553L	553	Missense	distal	5	no	157.366	158.135	EPSD	COSMIC	140.458	Up-regulation
CMGC_MAPK_JNK_MAPK9_ST	P10636	MAPT	P45984	MAPK9	T548	P549L	549	Missense	proximal	1	no	157.366	112.464	EPSD	COSMIC	140.458	Loss
CMGC_MAPK_JNK_MAPK9_ST	P10636	MAPT	P45984	MAPK9	T548	S555F	555	Missense	distal	7	no	157.366	158.162	EPSD	COSMIC	140.458	Up-regulation
CMGC_MAPK_JNK_MAPK9_ST	P10636	MAPT	P45984	MAPK9	T548	P553Q	553	Missense	distal	5	no	157.366	157.402	EPSD	COSMIC	140.458	Up-regulation
CMGC_MAPK_JNK_MAPK9_ST	P10636	MAPT	P45984	MAPK9	S552	P550S	550	Missense	proximal	-2	no	154.476	150.715	EPSD	COSMIC	140.458	Down-regulation
CMGC_MAPK_JNK_MAPK9_ST	P10636	MAPT	P45984	MAPK9	S552	R559C	559	Missense	distal	7	no	154.476	155.149	EPSD	COSMIC	140.458	Up-regulation
CMGC_MAPK_JNK_MAPK9_ST	P10636	MAPT	P45984	MAPK9	S552	P553R	553	Missense	proximal	1	no	154.476	116.888	EPSD	COSMIC	140.458	Loss
CMGC_MAPK_JNK_MAPK9_ST	P10636	MAPT	P45984	MAPK9	S552	P553L	553	Missense	proximal	1	no	154.476	109.573	EPSD	COSMIC	140.458	Loss
CMGC_MAPK_JNK_MAPK9_ST	P10636	MAPT	P45984	MAPK9	S552	P549L	549	Missense	distal	-3	no	154.476	152.903	EPSD	COSMIC	140.458	Down-regulation
CMGC_MAPK_JNK_MAPK9_ST	P10636	MAPT	P45984	MAPK9	S552	S555F	555	Missense	distal	3	no	154.476	154.124	EPSD	COSMIC	140.458	Down-regulation
CMGC_MAPK_JNK_MAPK9_ST	P10636	MAPT	P45984	MAPK9	S552	P553Q	553	Missense	proximal	1	no	154.476	134.364	EPSD	COSMIC	140.458	Loss
CMGC_MAPK_JNK_MAPK9_ST	P10636	MAPT	P45984	MAPK9	S555	P550S	550	Missense	distal	-5	no	142.317	142.297	EPSD	COSMIC	140.458	Down-regulation
CMGC_MAPK_JNK_MAPK9_ST	P10636	MAPT	P45984	MAPK9	S555	R559C	559	Missense	distal	4	no	142.317	142.574	EPSD	COSMIC	140.458	Up-regulation
CMGC_MAPK_JNK_MAPK9_ST	P10636	MAPT	P45984	MAPK9	S555	P553R	553	Missense	proximal	-2	no	142.317	141.114	EPSD	COSMIC	140.458	Down-regulation
CMGC_MAPK_JNK_MAPK9_ST	P10636	MAPT	P45984	MAPK9	S555	P553L	553	Missense	proximal	-2	no	142.317	141.242	EPSD	COSMIC	140.458	Down-regulation
CMGC_MAPK_JNK_MAPK9_ST	P10636	MAPT	P45984	MAPK9	S555	P549L	549	Missense	distal	-6	no	142.317	141.875	EPSD	COSMIC	140.458	Down-regulation
CMGC_MAPK_JNK_MAPK9_ST	P10636	MAPT	P45984	MAPK9	S555	S555F	555	Missense	central	0	yes	142.317	0.000	EPSD	COSMIC	140.458	Loss
CMGC_MAPK_JNK_MAPK9_ST	P10636	MAPT	P45984	MAPK9	S555	P553Q	553	Missense	proximal	-2	no	142.317	141.116	EPSD	COSMIC	140.458	Down-regulation
CMGC_MAPK_JNK_MAPK9_ST	P10636	MAPT	P45984	MAPK9	T562	V565M	565	Missense	distal	3	no	144.903	145.041	EPSD	COSMIC	140.458	Up-regulation
CMGC_MAPK_JNK_MAPK9_ST	P10636	MAPT	P45984	MAPK9	T562	P566S	566	Missense	distal	4	no	144.903	145.006	EPSD	COSMIC	140.458	Up-regulation
CMGC_MAPK_JNK_MAPK9_ST	P10636	MAPT	P45984	MAPK9	T562	R559C	559	Missense	distal	-3	no	144.903	143.345	EPSD	COSMIC	140.458	Down-regulation
CMGC_MAPK_JNK_MAPK9_ST	P10636	MAPT	P45984	MAPK9	T562	S555F	555	Missense	distal	-7	no	144.903	141.965	EPSD	COSMIC	140.458	Down-regulation
CMGC_MAPK_JNK_MAPK9_ST	P10636	MAPT	P45984	MAPK9	T562	P568S	568	Missense	distal	6	no	144.903	144.930	EPSD	COSMIC	140.458	Up-regulation
CMGC_MAPK_JNK_MAPK9_ST	P10636	MAPT	P45984	MAPK9	S579	T580N	580	Missense	proximal	1	no	141.032	-40.141	EPSD	COSMIC	140.458	Loss
CMGC_MAPK_JNK_MAPK9_ST	P10636	MAPT	P45984	MAPK9	S579	G578S	578	Missense	proximal	-1	no	141.032	141.094	EPSD	COSMIC	140.458	Up-regulation
CMGC_MAPK_JNK_MAPK9_ST	P10636	MAPT	P45984	MAPK9	T703	R696H	696	Missense	distal	-7	no	143.500	141.756	EPSD	COSMIC	140.458	Down-regulation
CMGC_MAPK_JNK_MAPK9_ST	P10636	MAPT	P45984	MAPK9	T703	E708D	708	Missense	distal	5	no	143.500	144.041	EPSD	COSMIC	140.458	Up-regulation
CMGC_MAPK_JNK_MAPK9_ST	P10636	MAPT	P45984	MAPK9	T703	G706R	706	Missense	distal	3	no	143.500	143.816	EPSD	COSMIC	140.458	Up-regulation
CMGC_MAPK_JNK_MAPK9_ST	P10636	MAPT	P45984	MAPK9	T703	V710M	710	Missense	distal	7	no	143.500	143.071	EPSD	COSMIC	140.458	Down-regulation
CMGC_MAPK_JNK_MAPK9_ST	P10636	MAPT	P45984	MAPK9	T703	E708K	708	Missense	distal	5	no	143.500	143.645	EPSD	COSMIC	140.458	Up-regulation
CMGC_MAPK_JNK_MAPK9_ST	P10636	MAPT	P45984	MAPK9	T703	R696C	696	Missense	distal	-7	no	143.500	141.647	EPSD	COSMIC	140.458	Down-regulation
CMGC_MAPK_JNK_MAPK9_ST	P10636	MAPT	P45984	MAPK9	T703	V710A	710	Missense	distal	7	no	143.500	142.826	EPSD	COSMIC	140.458	Down-regulation
CMGC_MAPK_JNK_MAPK9_ST	P10636	MAPT	P45984	MAPK9	T703	T703I	703	Missense	central	0	yes	143.500	0.000	EPSD	COSMIC	140.458	Loss
CMGC_MAPK_JNK_MAPK9_ST	P10636	MAPT	P45984	MAPK9	S713	E708D	708	Missense	distal	-5	no	148.590	148.695	EPSD	COSMIC	140.458	Up-regulation
CMGC_MAPK_JNK_MAPK9_ST	P10636	MAPT	P45984	MAPK9	S713	G706R	706	Missense	distal	-7	no	148.590	149.537	EPSD	COSMIC	140.458	Up-regulation
CMGC_MAPK_JNK_MAPK9_ST	P10636	MAPT	P45984	MAPK9	S713	V710M	710	Missense	distal	-3	no	148.590	149.857	EPSD	COSMIC	140.458	Up-regulation
CMGC_MAPK_JNK_MAPK9_ST	P10636	MAPT	P45984	MAPK9	S713	E708K	708	Missense	distal	-5	no	148.590	148.623	EPSD	COSMIC	140.458	Up-regulation
CMGC_MAPK_JNK_MAPK9_ST	P10636	MAPT	P45984	MAPK9	S713	V710A	710	Missense	distal	-3	no	148.590	150.055	EPSD	COSMIC	140.458	Up-regulation
CMGC_MAPK_JNK_MAPK9_ST	P10636	MAPT	P45984	MAPK9	S721	R723W	723	Missense	proximal	2	no	151.648	151.975	EPSD	COSMIC	140.458	Up-regulation
CMGC_MAPK_JNK_MAPK9_ST	P10636	MAPT	P45984	MAPK9	S721	V728M	728	Missense	distal	7	no	151.648	151.219	EPSD	COSMIC	140.458	Down-regulation
CMGC_MAPK_JNK_MAPK9_ST	P10636	MAPT	P45984	MAPK9	S721	V728A	728	Missense	distal	7	no	151.648	150.974	EPSD	COSMIC	140.458	Down-regulation
CMGC_MAPK_JNK_MAPK9_ST	P10636	MAPT	P45984	MAPK9	S739	G732S	732	Missense	distal	-7	no	150.893	151.260	EPSD	COSMIC	140.458	Up-regulation
CMGC_MAPK_JNK_MAPK9_ST	P10636	MAPT	P45984	MAPK9	S739	D735N	735	Missense	distal	-4	no	150.893	152.914	EPSD	COSMIC	140.458	Up-regulation
CMGC_MAPK_JNK_MAPK9_ST	P10636	MAPT	P45984	MAPK9	S739	G732C	732	Missense	distal	-7	no	150.893	149.986	EPSD	COSMIC	140.458	Down-regulation
CMGC_MAPK_JNK_MAPK9_ST	P10636	MAPT	P45984	MAPK9	S739	T744M	744	Missense	distal	5	no	150.893	150.421	EPSD	COSMIC	140.458	Down-regulation
CMGC_MAPK_JNK_MAPK9_ST	P10636	MAPT	P45984	MAPK9	S739	A743T	743	Missense	distal	4	no	150.893	151.064	EPSD	COSMIC	140.458	Up-regulation
CMGC_MAPK_JNK_MAPK9_ST	P10636	MAPT	P45984	MAPK9	S750	E748K	748	Missense	proximal	-2	no	141.536	139.468	EPSD	COSMIC	140.458	Loss
CMGC_MAPK_JNK_MAPK9_ST	P10636	MAPT	P45984	MAPK9	S750	T744M	744	Missense	distal	-6	no	141.536	141.996	EPSD	COSMIC	140.458	Up-regulation
CMGC_MAPK_JNK_MAPK9_ST	P10636	MAPT	P45984	MAPK9	S750	A743T	743	Missense	distal	-7	no	141.536	138.993	EPSD	COSMIC	140.458	Loss
CMGC_MAPK_JNK_MAPK9_ST	P15336	ATF2	P45984	MAPK9	T69	T73A	73	Missense	distal	4	no	157.619	157.448	PhosphoSitePlus;EPSD	COSMIC	140.458	Down-regulation
CMGC_MAPK_JNK_MAPK9_ST	P15336	ATF2	P45984	MAPK9	T69	F75L	75	Missense	distal	6	no	157.619	157.910	PhosphoSitePlus;EPSD	COSMIC	140.458	Up-regulation
CMGC_MAPK_JNK_MAPK9_ST	P15336	ATF2	P45984	MAPK9	T69	R74T	74	Missense	distal	5	no	157.619	158.241	PhosphoSitePlus;EPSD	COSMIC	140.458	Up-regulation
CMGC_MAPK_JNK_MAPK9_ST	P15336	ATF2	P45984	MAPK9	T69	I64V	64	Missense	distal	-5	no	157.619	157.597	PhosphoSitePlus;EPSD	COSMIC	140.458	Down-regulation
CMGC_MAPK_JNK_MAPK9_ST	P15336	ATF2	P45984	MAPK9	T69	D67E	67	Missense	proximal	-2	no	157.619	159.608	PhosphoSitePlus;EPSD	COSMIC	140.458	Up-regulation
CMGC_MAPK_JNK_MAPK9_ST	P15336	ATF2	P45984	MAPK9	T71	T73A	73	Missense	proximal	2	no	157.277	157.111	EPSD;PhosphoSitePlus	COSMIC	140.458	Down-regulation
CMGC_MAPK_JNK_MAPK9_ST	P15336	ATF2	P45984	MAPK9	T71	F75L	75	Missense	distal	4	no	157.277	157.046	EPSD;PhosphoSitePlus	COSMIC	140.458	Down-regulation
CMGC_MAPK_JNK_MAPK9_ST	P15336	ATF2	P45984	MAPK9	T71	R74T	74	Missense	distal	3	no	157.277	157.006	EPSD;PhosphoSitePlus	COSMIC	140.458	Down-regulation
CMGC_MAPK_JNK_MAPK9_ST	P15336	ATF2	P45984	MAPK9	T71	I64V	64	Missense	distal	-7	no	157.277	157.189	EPSD;PhosphoSitePlus	COSMIC	140.458	Down-regulation
CMGC_MAPK_JNK_MAPK9_ST	P15336	ATF2	P45984	MAPK9	T71	D67E	67	Missense	distal	-4	no	157.277	158.196	EPSD;PhosphoSitePlus	COSMIC	140.458	Up-regulation
CMGC_MAPK_JNK_MAPK9_ST	P15336	ATF2	P45984	MAPK9	S90	P91S	91	Missense	proximal	1	no	161.846	-118.948	EPSD;PhosphoSitePlus	COSMIC	140.458	Loss
CMGC_MAPK_JNK_MAPK9_ST	P15336	ATF2	P45984	MAPK9	S90	A89V	89	Missense	proximal	-1	no	161.846	161.618	EPSD;PhosphoSitePlus	COSMIC	140.458	Down-regulation
CMGC_MAPK_JNK_MAPK9_ST	P15336	ATF2	P45984	MAPK9	S90	P91L	91	Missense	proximal	1	no	161.846	116.944	EPSD;PhosphoSitePlus	COSMIC	140.458	Loss
CMGC_MAPK_JNK_MAPK9_ST	P15336	ATF2	P45984	MAPK9	S90	G83C	83	Missense	distal	-7	no	161.846	160.939	EPSD;PhosphoSitePlus	COSMIC	140.458	Down-regulation
CMGC_MAPK_JNK_MAPK9_ST	P15336	ATF2	P45984	MAPK9	S112	M107I	107	Missense	distal	-5	no	155.989	156.098	EPSD	COSMIC;GDSC;CCLE	140.458	Up-regulation
CMGC_MAPK_JNK_MAPK9_ST	P15336	ATF2	P45984	MAPK9	S112	K105T	105	Missense	distal	-7	no	155.989	154.116	EPSD	COSMIC;GDSC;CCLE	140.458	Down-regulation
CMGC_MAPK_JNK_MAPK9_ST	P15336	ATF2	P45984	MAPK9	S112	K106R	106	Missense	distal	-6	no	155.989	156.176	EPSD	COSMIC	140.458	Up-regulation
CMGC_MAPK_JNK_MAPK9_ST	P15336	ATF2	P45984	MAPK9	S112	D110E	110	Missense	proximal	-2	no	155.989	157.978	EPSD	COSMIC	140.458	Up-regulation
CMGC_MAPK_JNK_MAPK9_ST	P15336	ATF2	P45984	MAPK9	T116	D110E	110	Missense	distal	-6	no	159.246	159.809	EPSD	COSMIC	140.458	Up-regulation
CMGC_MAPK_JNK_MAPK9_ST	P15336	ATF2	P45984	MAPK9	T131	E125K	125	Missense	distal	-6	no	141.821	141.680	EPSD	COSMIC	140.458	Down-regulation
CMGC_MAPK_JNK_MAPK9_ST	P15336	ATF2	P45984	MAPK9	T131	P137S	137	Missense	distal	6	no	141.821	141.847	EPSD	COSMIC	140.458	Up-regulation
CMGC_MAPK_JNK_MAPK9_ST	P15336	ATF2	P45984	MAPK9	T131	S127F	127	Missense	distal	-4	no	141.821	138.538	EPSD	COSMIC	140.458	Loss
CMGC_MAPK_JNK_MAPK9_ST	P15336	ATF2	P45984	MAPK9	S136	P141T	141	Missense	distal	5	no	153.807	154.256	EPSD	COSMIC	140.458	Up-regulation
CMGC_MAPK_JNK_MAPK9_ST	P15336	ATF2	P45984	MAPK9	S136	P141L	141	Missense	distal	5	no	153.807	154.576	EPSD	COSMIC	140.458	Up-regulation
CMGC_MAPK_JNK_MAPK9_ST	P15336	ATF2	P45984	MAPK9	S136	P137S	137	Missense	proximal	1	no	153.807	-126.987	EPSD	COSMIC	140.458	Loss
CMGC_MAPK_JNK_MAPK9_ST	P15336	ATF2	P45984	MAPK9	S265	S266P	266	Missense	proximal	1	no	-130.061	150.733	EPSD	COSMIC	140.458	Gain
CMGC_MAPK_JNK_MAPK9_ST	P15336	ATF2	P45984	MAPK9	S266	S266P	266	Missense	central	0	yes	157.676	0.000	EPSD	COSMIC	140.458	Loss
CMGC_MAPK_JNK_MAPK9_ST	P15336	ATF2	P45984	MAPK9	S266	P269Q	269	Missense	distal	3	no	157.676	157.761	EPSD	COSMIC	140.458	Up-regulation
CMGC_MAPK_JNK_MAPK9_ST	P15336	ATF2	P45984	MAPK9	S266	S265F	265	Missense	proximal	-1	no	157.676	157.300	EPSD	COSMIC;GDSC;CCLE	140.458	Down-regulation
CMGC_MAPK_JNK_MAPK9_ST	P15336	ATF2	P45984	MAPK9	S266	P269S	269	Missense	distal	3	no	157.676	157.628	EPSD	COSMIC	140.458	Down-regulation
CMGC_MAPK_JNK_MAPK9_ST	P15336	ATF2	P45984	MAPK9	T283	P287S	287	Missense	distal	4	no	144.509	144.611	EPSD	COSMIC	140.458	Up-regulation
CMGC_MAPK_JNK_MAPK9_ST	P15336	ATF2	P45984	MAPK9	T325	P326L	326	Missense	proximal	1	no	157.279	112.376	EPSD	COSMIC;GDSC	140.458	Loss
CMGC_MAPK_JNK_MAPK9_ST	P15336	ATF2	P45984	MAPK9	T325	P326T	326	Missense	proximal	1	no	157.279	138.083	EPSD	COSMIC	140.458	Loss
CMGC_MAPK_JNK_MAPK9_ST	P15336	ATF2	P45984	MAPK9	T325	H331Y	331	Missense	distal	6	no	157.279	157.052	EPSD	COSMIC	140.458	Down-regulation
CMGC_MAPK_JNK_MAPK9_ST	P15336	ATF2	P45984	MAPK9	S328	P326L	326	Missense	proximal	-2	no	160.859	159.785	EPSD	COSMIC;GDSC	140.458	Down-regulation
CMGC_MAPK_JNK_MAPK9_ST	P15336	ATF2	P45984	MAPK9	S328	P326T	326	Missense	proximal	-2	no	160.859	157.223	EPSD	COSMIC	140.458	Down-regulation
CMGC_MAPK_JNK_MAPK9_ST	P15336	ATF2	P45984	MAPK9	S328	Q335H	335	Missense	distal	7	no	160.859	161.213	EPSD	COSMIC	140.458	Up-regulation
CMGC_MAPK_JNK_MAPK9_ST	P15336	ATF2	P45984	MAPK9	S328	P334S	334	Missense	distal	6	no	160.859	160.886	EPSD	COSMIC	140.458	Up-regulation
CMGC_MAPK_JNK_MAPK9_ST	P15336	ATF2	P45984	MAPK9	S328	H331Y	331	Missense	distal	3	no	160.859	160.574	EPSD	COSMIC	140.458	Down-regulation
CMGC_MAPK_JNK_MAPK9_ST	P15336	ATF2	P45984	MAPK9	T333	Q337K	337	Missense	distal	4	no	152.446	152.565	EPSD	COSMIC	140.458	Up-regulation
CMGC_MAPK_JNK_MAPK9_ST	P15336	ATF2	P45984	MAPK9	T333	P326L	326	Missense	distal	-7	no	152.446	151.319	EPSD	COSMIC;GDSC	140.458	Down-regulation
CMGC_MAPK_JNK_MAPK9_ST	P15336	ATF2	P45984	MAPK9	T333	P326T	326	Missense	distal	-7	no	152.446	152.054	EPSD	COSMIC	140.458	Down-regulation
CMGC_MAPK_JNK_MAPK9_ST	P15336	ATF2	P45984	MAPK9	T333	Q335H	335	Missense	proximal	2	no	152.446	152.584	EPSD	COSMIC	140.458	Up-regulation
CMGC_MAPK_JNK_MAPK9_ST	P15336	ATF2	P45984	MAPK9	T333	P334S	334	Missense	proximal	1	no	152.446	-128.348	EPSD	COSMIC	140.458	Loss
CMGC_MAPK_JNK_MAPK9_ST	P15336	ATF2	P45984	MAPK9	T333	H331Y	331	Missense	proximal	-2	no	152.446	150.954	EPSD	COSMIC	140.458	Down-regulation
CMGC_MAPK_JNK_MAPK9_ST	P15336	ATF2	P45984	MAPK9	S338	Q337K	337	Missense	proximal	-1	no	141.803	141.708	EPSD	COSMIC	140.458	Down-regulation
CMGC_MAPK_JNK_MAPK9_ST	P15336	ATF2	P45984	MAPK9	S338	Q335H	335	Missense	distal	-3	no	141.803	139.639	EPSD	COSMIC	140.458	Loss
CMGC_MAPK_JNK_MAPK9_ST	P15336	ATF2	P45984	MAPK9	S338	R343L	343	Missense	distal	5	no	141.803	142.745	EPSD	COSMIC	140.458	Up-regulation
CMGC_MAPK_JNK_MAPK9_ST	P15336	ATF2	P45984	MAPK9	S338	P334S	334	Missense	distal	-4	no	141.803	141.982	EPSD	COSMIC	140.458	Up-regulation
CMGC_MAPK_JNK_MAPK9_ST	P15336	ATF2	P45984	MAPK9	S338	H331Y	331	Missense	distal	-7	no	141.803	139.756	EPSD	COSMIC	140.458	Loss
CMGC_MAPK_JNK_MAPK9_ST	P15336	ATF2	P45984	MAPK9	S338	R345T	345	Missense	distal	7	no	141.803	142.519	EPSD	COSMIC	140.458	Up-regulation
CMGC_MAPK_JNK_MAPK9_ST	P15336	ATF2	P45984	MAPK9	S338	R343Q	343	Missense	distal	5	no	141.803	142.012	EPSD	COSMIC	140.458	Up-regulation
CMGC_MAPK_JNK_MAPK9_ST	P15336	ATF2	P45984	MAPK9	S338	R345K	345	Missense	distal	7	no	141.803	142.338	EPSD	COSMIC	140.458	Up-regulation
CMGC_MAPK_JNK_MAPK9_ST	P15336	ATF2	P45984	MAPK9	S446	S442L	442	Missense	distal	-4	no	154.824	152.632	EPSD	COSMIC	140.458	Down-regulation
CMGC_MAPK_JNK_MAPK9_ST	P15336	ATF2	P45984	MAPK9	S446	P444L	444	Missense	proximal	-2	no	154.824	153.749	EPSD	COSMIC	140.458	Down-regulation
CMGC_MAPK_JNK_MAPK9_ST	P15336	ATF2	P45984	MAPK9	S446	P444T	444	Missense	proximal	-2	no	154.824	151.187	EPSD	COSMIC	140.458	Down-regulation
CMGC_MAPK_JNK_MAPK9_ST	P15336	ATF2	P45984	MAPK9	S446	S442P	442	Missense	distal	-4	no	154.824	154.645	EPSD	COSMIC	140.458	Down-regulation
CMGC_MAPK_JNK_MAPK9_ST	P15336	ATF2	P45984	MAPK9	S446	P444Q	444	Missense	proximal	-2	no	154.824	153.623	EPSD	COSMIC	140.458	Down-regulation
CMGC_MAPK_JNK_MAPK9_ST	P01106	MYC	P45984	MAPK9	T58	P57S	57	Missense	proximal	-1	no	162.904	162.791	EPSD	COSMIC;CCLE	140.458	Down-regulation
CMGC_MAPK_JNK_MAPK9_ST	P01106	MYC	P45984	MAPK9	T58	S62P	62	Missense	distal	4	no	162.904	162.802	EPSD	COSMIC;CCLE	140.458	Down-regulation
CMGC_MAPK_JNK_MAPK9_ST	P01106	MYC	P45984	MAPK9	T58	P59L	59	Missense	proximal	1	no	162.904	118.001	EPSD	COSMIC;CCLE	140.458	Loss
CMGC_MAPK_JNK_MAPK9_ST	P01106	MYC	P45984	MAPK9	T58	T58N	58	Missense	central	0	yes	162.904	0.000	EPSD	COSMIC;CCLE	140.458	Loss
CMGC_MAPK_JNK_MAPK9_ST	P01106	MYC	P45984	MAPK9	T58	P60H	60	Missense	proximal	2	no	162.904	163.061	EPSD	COSMIC;CCLE	140.458	Up-regulation
CMGC_MAPK_JNK_MAPK9_ST	P01106	MYC	P45984	MAPK9	T58	P63L	63	Missense	distal	5	no	162.904	163.673	EPSD	COSMIC	140.458	Up-regulation
CMGC_MAPK_JNK_MAPK9_ST	P01106	MYC	P45984	MAPK9	T58	P63H	63	Missense	distal	5	no	162.904	163.481	EPSD	COSMIC	140.458	Up-regulation
CMGC_MAPK_JNK_MAPK9_ST	P01106	MYC	P45984	MAPK9	T58	T58A	58	Missense	central	0	yes	162.904	0.000	EPSD	COSMIC;CCLE	140.458	Loss
CMGC_MAPK_JNK_MAPK9_ST	P01106	MYC	P45984	MAPK9	T58	P59A	59	Missense	proximal	1	no	162.904	144.260	EPSD	COSMIC;CCLE	140.458	Down-regulation
CMGC_MAPK_JNK_MAPK9_ST	P01106	MYC	P45984	MAPK9	T58	P59R	59	Missense	proximal	1	no	162.904	125.316	EPSD	COSMIC	140.458	Loss
CMGC_MAPK_JNK_MAPK9_ST	P01106	MYC	P45984	MAPK9	T58	P60A	60	Missense	proximal	2	no	162.904	162.914	EPSD	COSMIC;CCLE	140.458	Up-regulation
CMGC_MAPK_JNK_MAPK9_ST	P01106	MYC	P45984	MAPK9	T58	P57T	57	Missense	proximal	-1	no	162.904	162.614	EPSD	COSMIC;CCLE	140.458	Down-regulation
CMGC_MAPK_JNK_MAPK9_ST	P01106	MYC	P45984	MAPK9	T58	P59S	59	Missense	proximal	1	no	162.904	-117.890	EPSD	COSMIC;CCLE	140.458	Loss
CMGC_MAPK_JNK_MAPK9_ST	P01106	MYC	P45984	MAPK9	T58	S62F	62	Missense	distal	4	no	162.904	163.409	EPSD	COSMIC	140.458	Up-regulation
CMGC_MAPK_JNK_MAPK9_ST	P01106	MYC	P45984	MAPK9	T58	T58I	58	Missense	central	0	yes	162.904	0.000	EPSD	COSMIC;CCLE	140.458	Loss
CMGC_MAPK_JNK_MAPK9_ST	P01106	MYC	P45984	MAPK9	T58	K51N	51	Missense	distal	-7	no	162.904	164.340	EPSD	COSMIC	140.458	Up-regulation
CMGC_MAPK_JNK_MAPK9_ST	P01106	MYC	P45984	MAPK9	T58	T58P	58	Missense	central	0	yes	162.904	0.000	EPSD	COSMIC	140.458	Loss
CMGC_MAPK_JNK_MAPK9_ST	P01106	MYC	P45984	MAPK9	T58	S64R	64	Missense	distal	6	no	162.904	162.941	EPSD	COSMIC;CCLE	140.458	Up-regulation
CMGC_MAPK_JNK_MAPK9_ST	P01106	MYC	P45984	MAPK9	T58	P57L	57	Missense	proximal	-1	no	162.904	162.748	EPSD	COSMIC;CCLE	140.458	Down-regulation
CMGC_MAPK_JNK_MAPK9_ST	P01106	MYC	P45984	MAPK9	T58	P63S	63	Missense	distal	5	no	162.904	162.962	EPSD	COSMIC;CCLE	140.458	Up-regulation
CMGC_MAPK_JNK_MAPK9_ST	P01106	MYC	P45984	MAPK9	T58	P57F	57	Missense	proximal	-1	no	162.904	162.416	EPSD	COSMIC	140.458	Down-regulation
CMGC_MAPK_JNK_MAPK9_ST	P01106	MYC	P45984	MAPK9	T58	P59Q	59	Missense	proximal	1	no	162.904	142.792	EPSD	COSMIC;CCLE	140.458	Down-regulation
CMGC_MAPK_JNK_MAPK9_ST	P01106	MYC	P45984	MAPK9	T58	P59T	59	Missense	proximal	1	no	162.904	143.708	EPSD	COSMIC	140.458	Down-regulation
CMGC_MAPK_JNK_MAPK9_ST	P01106	MYC	P45984	MAPK9	T58	P60S	60	Missense	proximal	2	no	162.904	162.999	EPSD	COSMIC	140.458	Up-regulation
CMGC_MAPK_JNK_MAPK9_ST	P01106	MYC	P45984	MAPK9	T58	P63A	63	Missense	distal	5	no	162.904	162.974	EPSD	COSMIC	140.458	Up-regulation
CMGC_MAPK_JNK_MAPK9_ST	P01106	MYC	P45984	MAPK9	T58	S64N	64	Missense	distal	6	no	162.904	163.207	EPSD	COSMIC	140.458	Up-regulation
CMGC_MAPK_JNK_MAPK9_ST	P01106	MYC	P45984	MAPK9	T58	P60L	60	Missense	proximal	2	no	162.904	163.059	EPSD	COSMIC	140.458	Up-regulation
CMGC_MAPK_JNK_MAPK9_ST	P01106	MYC	P45984	MAPK9	T58	P57A	57	Missense	proximal	-1	no	162.904	162.874	EPSD	COSMIC	140.458	Down-regulation
CMGC_MAPK_JNK_MAPK9_ST	P01106	MYC	P45984	MAPK9	T58	L56V	56	Missense	proximal	-2	no	162.904	159.703	EPSD	COSMIC	140.458	Down-regulation
CMGC_MAPK_JNK_MAPK9_ST	P01106	MYC	P45984	MAPK9	T58	P63R	63	Missense	distal	5	no	162.904	162.730	EPSD	COSMIC	140.458	Down-regulation
CMGC_MAPK_JNK_MAPK9_ST	P01106	MYC	P45984	MAPK9	T58	L56M	56	Missense	proximal	-2	no	162.904	162.110	EPSD	COSMIC	140.458	Down-regulation
CMGC_MAPK_JNK_MAPK9_ST	P01106	MYC	P45984	MAPK9	T58	P63T	63	Missense	distal	5	no	162.904	163.353	EPSD	COSMIC	140.458	Up-regulation
CMGC_MAPK_JNK_MAPK9_ST	P01106	MYC	P45984	MAPK9	T58	S62A	62	Missense	distal	4	no	162.904	162.830	EPSD	COSMIC	140.458	Down-regulation
CMGC_MAPK_JNK_MAPK9_ST	P01106	MYC	P45984	MAPK9	T58	P57R	57	Missense	proximal	-1	no	162.904	162.927	EPSD	COSMIC	140.458	Up-regulation
CMGC_MAPK_JNK_MAPK9_ST	P01106	MYC	P45984	MAPK9	T58	P60T	60	Missense	proximal	2	no	162.904	163.080	EPSD	COSMIC;CCLE	140.458	Up-regulation
CMGC_MAPK_JNK_MAPK9_ST	P01106	MYC	P45984	MAPK9	T58	E54V	54	Missense	distal	-4	no	162.904	161.586	EPSD	COSMIC	140.458	Down-regulation
CMGC_MAPK_JNK_MAPK9_ST	P01106	MYC	P45984	MAPK9	T58	S64T	64	Missense	distal	6	no	162.904	162.628	EPSD	COSMIC	140.458	Down-regulation
CMGC_MAPK_JNK_MAPK9_ST	P01106	MYC	P45984	MAPK9	T58	R65C	65	Missense	distal	7	no	162.904	163.577	EPSD	COSMIC	140.458	Up-regulation
CMGC_MAPK_JNK_MAPK9_ST	P01106	MYC	P45984	MAPK9	T58	L55P	55	Missense	distal	-3	no	162.904	164.477	EPSD	COSMIC	140.458	Up-regulation
CMGC_MAPK_JNK_MAPK9_ST	P01106	MYC	P45984	MAPK9	T58	L55M	55	Missense	distal	-3	no	162.904	163.654	EPSD	COSMIC	140.458	Up-regulation
CMGC_MAPK_JNK_MAPK9_ST	P01106	MYC	P45984	MAPK9	T58	E54A	54	Missense	distal	-4	no	162.904	163.242	EPSD	COSMIC	140.458	Up-regulation
CMGC_MAPK_JNK_MAPK9_ST	P01106	MYC	P45984	MAPK9	S62	P57S	57	Missense	distal	-5	no	156.539	156.520	EPSD;PhosphoSitePlus	COSMIC;CCLE	140.458	Down-regulation
CMGC_MAPK_JNK_MAPK9_ST	P01106	MYC	P45984	MAPK9	S62	S62P	62	Missense	central	0	yes	156.539	0.000	EPSD;PhosphoSitePlus	COSMIC;CCLE	140.458	Loss
CMGC_MAPK_JNK_MAPK9_ST	P01106	MYC	P45984	MAPK9	S62	P59L	59	Missense	distal	-3	no	156.539	154.966	EPSD;PhosphoSitePlus	COSMIC;CCLE	140.458	Down-regulation
CMGC_MAPK_JNK_MAPK9_ST	P01106	MYC	P45984	MAPK9	S62	T58N	58	Missense	distal	-4	no	156.539	159.928	EPSD;PhosphoSitePlus	COSMIC;CCLE	140.458	Up-regulation
CMGC_MAPK_JNK_MAPK9_ST	P01106	MYC	P45984	MAPK9	S62	P60H	60	Missense	proximal	-2	no	156.539	152.509	EPSD;PhosphoSitePlus	COSMIC;CCLE	140.458	Down-regulation
CMGC_MAPK_JNK_MAPK9_ST	P01106	MYC	P45984	MAPK9	S62	P63L	63	Missense	proximal	1	no	156.539	111.637	EPSD;PhosphoSitePlus	COSMIC	140.458	Loss
CMGC_MAPK_JNK_MAPK9_ST	P01106	MYC	P45984	MAPK9	S62	P63H	63	Missense	proximal	1	no	156.539	-3.567	EPSD;PhosphoSitePlus	COSMIC	140.458	Loss
CMGC_MAPK_JNK_MAPK9_ST	P01106	MYC	P45984	MAPK9	S62	T58A	58	Missense	distal	-4	no	156.539	159.165	EPSD;PhosphoSitePlus	COSMIC;CCLE	140.458	Up-regulation
CMGC_MAPK_JNK_MAPK9_ST	P01106	MYC	P45984	MAPK9	S62	P59A	59	Missense	distal	-3	no	156.539	155.914	EPSD;PhosphoSitePlus	COSMIC;CCLE	140.458	Down-regulation
CMGC_MAPK_JNK_MAPK9_ST	P01106	MYC	P45984	MAPK9	S62	P59R	59	Missense	distal	-3	no	156.539	156.219	EPSD;PhosphoSitePlus	COSMIC	140.458	Down-regulation
CMGC_MAPK_JNK_MAPK9_ST	P01106	MYC	P45984	MAPK9	S62	P60A	60	Missense	proximal	-2	no	156.539	155.269	EPSD;PhosphoSitePlus	COSMIC;CCLE	140.458	Down-regulation
CMGC_MAPK_JNK_MAPK9_ST	P01106	MYC	P45984	MAPK9	S62	P57T	57	Missense	distal	-5	no	156.539	156.566	EPSD;PhosphoSitePlus	COSMIC;CCLE	140.458	Up-regulation
CMGC_MAPK_JNK_MAPK9_ST	P01106	MYC	P45984	MAPK9	S62	P59S	59	Missense	distal	-3	no	156.539	155.500	EPSD;PhosphoSitePlus	COSMIC;CCLE	140.458	Down-regulation
CMGC_MAPK_JNK_MAPK9_ST	P01106	MYC	P45984	MAPK9	S62	S62F	62	Missense	central	0	yes	156.539	0.000	EPSD;PhosphoSitePlus	COSMIC	140.458	Loss
CMGC_MAPK_JNK_MAPK9_ST	P01106	MYC	P45984	MAPK9	S62	T58I	58	Missense	distal	-4	no	156.539	156.749	EPSD;PhosphoSitePlus	COSMIC;CCLE	140.458	Up-regulation
CMGC_MAPK_JNK_MAPK9_ST	P01106	MYC	P45984	MAPK9	S62	T58P	58	Missense	distal	-4	no	156.539	158.431	EPSD;PhosphoSitePlus	COSMIC	140.458	Up-regulation
CMGC_MAPK_JNK_MAPK9_ST	P01106	MYC	P45984	MAPK9	S62	S64R	64	Missense	proximal	2	no	156.539	156.418	EPSD;PhosphoSitePlus	COSMIC;CCLE	140.458	Down-regulation
CMGC_MAPK_JNK_MAPK9_ST	P01106	MYC	P45984	MAPK9	S62	P57L	57	Missense	distal	-5	no	156.539	156.639	EPSD;PhosphoSitePlus	COSMIC;CCLE	140.458	Up-regulation
CMGC_MAPK_JNK_MAPK9_ST	P01106	MYC	P45984	MAPK9	S62	P63S	63	Missense	proximal	1	no	156.539	-124.255	EPSD;PhosphoSitePlus	COSMIC;CCLE	140.458	Loss
CMGC_MAPK_JNK_MAPK9_ST	P01106	MYC	P45984	MAPK9	S62	R66H	66	Missense	distal	4	no	156.539	156.820	EPSD;PhosphoSitePlus	COSMIC	140.458	Up-regulation
CMGC_MAPK_JNK_MAPK9_ST	P01106	MYC	P45984	MAPK9	S62	P57F	57	Missense	distal	-5	no	156.539	156.663	EPSD;PhosphoSitePlus	COSMIC	140.458	Up-regulation
CMGC_MAPK_JNK_MAPK9_ST	P01106	MYC	P45984	MAPK9	S62	P59Q	59	Missense	distal	-3	no	156.539	155.996	EPSD;PhosphoSitePlus	COSMIC;CCLE	140.458	Down-regulation
CMGC_MAPK_JNK_MAPK9_ST	P01106	MYC	P45984	MAPK9	S62	P59T	59	Missense	distal	-3	no	156.539	154.666	EPSD;PhosphoSitePlus	COSMIC	140.458	Down-regulation
CMGC_MAPK_JNK_MAPK9_ST	P01106	MYC	P45984	MAPK9	S62	P60S	60	Missense	proximal	-2	no	156.539	152.778	EPSD;PhosphoSitePlus	COSMIC	140.458	Down-regulation
CMGC_MAPK_JNK_MAPK9_ST	P01106	MYC	P45984	MAPK9	S62	P63A	63	Missense	proximal	1	no	156.539	137.896	EPSD;PhosphoSitePlus	COSMIC	140.458	Loss
CMGC_MAPK_JNK_MAPK9_ST	P01106	MYC	P45984	MAPK9	S62	S64N	64	Missense	proximal	2	no	156.539	156.450	EPSD;PhosphoSitePlus	COSMIC	140.458	Down-regulation
CMGC_MAPK_JNK_MAPK9_ST	P01106	MYC	P45984	MAPK9	S62	P60L	60	Missense	proximal	-2	no	156.539	155.465	EPSD;PhosphoSitePlus	COSMIC	140.458	Down-regulation
CMGC_MAPK_JNK_MAPK9_ST	P01106	MYC	P45984	MAPK9	S62	P57A	57	Missense	distal	-5	no	156.539	156.528	EPSD;PhosphoSitePlus	COSMIC	140.458	Down-regulation
CMGC_MAPK_JNK_MAPK9_ST	P01106	MYC	P45984	MAPK9	S62	L56V	56	Missense	distal	-6	no	156.539	156.656	EPSD;PhosphoSitePlus	COSMIC	140.458	Up-regulation
CMGC_MAPK_JNK_MAPK9_ST	P01106	MYC	P45984	MAPK9	S62	P63R	63	Missense	proximal	1	no	156.539	118.951	EPSD;PhosphoSitePlus	COSMIC	140.458	Loss
CMGC_MAPK_JNK_MAPK9_ST	P01106	MYC	P45984	MAPK9	S62	L56M	56	Missense	distal	-6	no	156.539	157.082	EPSD;PhosphoSitePlus	COSMIC	140.458	Up-regulation
CMGC_MAPK_JNK_MAPK9_ST	P01106	MYC	P45984	MAPK9	S62	L69V	69	Missense	distal	7	no	156.539	156.498	EPSD;PhosphoSitePlus	COSMIC	140.458	Down-regulation
CMGC_MAPK_JNK_MAPK9_ST	P01106	MYC	P45984	MAPK9	S62	P63T	63	Missense	proximal	1	no	156.539	137.344	EPSD;PhosphoSitePlus	COSMIC	140.458	Loss
CMGC_MAPK_JNK_MAPK9_ST	P01106	MYC	P45984	MAPK9	S62	S67F	67	Missense	distal	5	no	156.539	157.727	EPSD;PhosphoSitePlus	COSMIC	140.458	Up-regulation
CMGC_MAPK_JNK_MAPK9_ST	P01106	MYC	P45984	MAPK9	S62	S62A	62	Missense	central	0	yes	156.539	0.000	EPSD;PhosphoSitePlus	COSMIC	140.458	Loss
CMGC_MAPK_JNK_MAPK9_ST	P01106	MYC	P45984	MAPK9	S62	P57R	57	Missense	distal	-5	no	156.539	156.531	EPSD;PhosphoSitePlus	COSMIC	140.458	Down-regulation
CMGC_MAPK_JNK_MAPK9_ST	P01106	MYC	P45984	MAPK9	S62	L69P	69	Missense	distal	7	no	156.539	155.900	EPSD;PhosphoSitePlus	COSMIC	140.458	Down-regulation
CMGC_MAPK_JNK_MAPK9_ST	P01106	MYC	P45984	MAPK9	S62	P60T	60	Missense	proximal	-2	no	156.539	152.903	EPSD;PhosphoSitePlus	COSMIC;CCLE	140.458	Down-regulation
CMGC_MAPK_JNK_MAPK9_ST	P01106	MYC	P45984	MAPK9	S62	L69F	69	Missense	distal	7	no	156.539	156.924	EPSD;PhosphoSitePlus	COSMIC	140.458	Up-regulation
CMGC_MAPK_JNK_MAPK9_ST	P01106	MYC	P45984	MAPK9	S62	S64T	64	Missense	proximal	2	no	156.539	156.620	EPSD;PhosphoSitePlus	COSMIC	140.458	Up-regulation
CMGC_MAPK_JNK_MAPK9_ST	P01106	MYC	P45984	MAPK9	S62	R65C	65	Missense	distal	3	no	156.539	156.247	EPSD;PhosphoSitePlus	COSMIC	140.458	Down-regulation
CMGC_MAPK_JNK_MAPK9_ST	P01106	MYC	P45984	MAPK9	S62	L55P	55	Missense	distal	-7	no	156.539	157.667	EPSD;PhosphoSitePlus	COSMIC	140.458	Up-regulation
CMGC_MAPK_JNK_MAPK9_ST	P01106	MYC	P45984	MAPK9	S62	L55M	55	Missense	distal	-7	no	156.539	159.053	EPSD;PhosphoSitePlus	COSMIC	140.458	Up-regulation
CMGC_MAPK_JNK_MAPK9_ST	P01106	MYC	P45984	MAPK9	S71	C70R	70	Missense	proximal	-1	no	158.457	158.638	PhosphoSitePlus;EPSD	COSMIC	140.458	Up-regulation
CMGC_MAPK_JNK_MAPK9_ST	P01106	MYC	P45984	MAPK9	S71	S64R	64	Missense	distal	-7	no	158.457	159.036	PhosphoSitePlus;EPSD	COSMIC;CCLE	140.458	Up-regulation
CMGC_MAPK_JNK_MAPK9_ST	P01106	MYC	P45984	MAPK9	S71	R66H	66	Missense	distal	-5	no	158.457	158.513	PhosphoSitePlus;EPSD	COSMIC	140.458	Up-regulation
CMGC_MAPK_JNK_MAPK9_ST	P01106	MYC	P45984	MAPK9	S71	A76V	76	Missense	distal	5	no	158.457	158.874	PhosphoSitePlus;EPSD	COSMIC	140.458	Up-regulation
CMGC_MAPK_JNK_MAPK9_ST	P01106	MYC	P45984	MAPK9	S71	V77I	77	Missense	distal	6	no	158.457	158.344	PhosphoSitePlus;EPSD	COSMIC;CCLE	140.458	Down-regulation
CMGC_MAPK_JNK_MAPK9_ST	P01106	MYC	P45984	MAPK9	S71	S71L	71	Missense	central	0	yes	158.457	0.000	PhosphoSitePlus;EPSD	COSMIC	140.458	Loss
CMGC_MAPK_JNK_MAPK9_ST	P01106	MYC	P45984	MAPK9	S71	S64N	64	Missense	distal	-7	no	158.457	160.343	PhosphoSitePlus;EPSD	COSMIC	140.458	Up-regulation
CMGC_MAPK_JNK_MAPK9_ST	P01106	MYC	P45984	MAPK9	S71	Y74N	74	Missense	distal	3	no	158.457	158.984	PhosphoSitePlus;EPSD	COSMIC;CCLE	140.458	Up-regulation
CMGC_MAPK_JNK_MAPK9_ST	P01106	MYC	P45984	MAPK9	S71	L69V	69	Missense	proximal	-2	no	158.457	155.256	PhosphoSitePlus;EPSD	COSMIC	140.458	Down-regulation
CMGC_MAPK_JNK_MAPK9_ST	P01106	MYC	P45984	MAPK9	S71	V77G	77	Missense	distal	6	no	158.457	158.427	PhosphoSitePlus;EPSD	COSMIC	140.458	Down-regulation
CMGC_MAPK_JNK_MAPK9_ST	P01106	MYC	P45984	MAPK9	S71	Y74H	74	Missense	distal	3	no	158.457	158.742	PhosphoSitePlus;EPSD	COSMIC	140.458	Up-regulation
CMGC_MAPK_JNK_MAPK9_ST	P01106	MYC	P45984	MAPK9	S71	S67F	67	Missense	distal	-4	no	158.457	155.174	PhosphoSitePlus;EPSD	COSMIC	140.458	Down-regulation
CMGC_MAPK_JNK_MAPK9_ST	P01106	MYC	P45984	MAPK9	S71	V75I	75	Missense	distal	4	no	158.457	158.497	PhosphoSitePlus;EPSD	COSMIC	140.458	Up-regulation
CMGC_MAPK_JNK_MAPK9_ST	P01106	MYC	P45984	MAPK9	S71	L69P	69	Missense	proximal	-2	no	158.457	159.531	PhosphoSitePlus;EPSD	COSMIC	140.458	Up-regulation
CMGC_MAPK_JNK_MAPK9_ST	P01106	MYC	P45984	MAPK9	S71	C70W	70	Missense	proximal	-1	no	158.457	158.161	PhosphoSitePlus;EPSD	COSMIC	140.458	Down-regulation
CMGC_MAPK_JNK_MAPK9_ST	P01106	MYC	P45984	MAPK9	S71	S71W	71	Missense	central	0	yes	158.457	0.000	PhosphoSitePlus;EPSD	COSMIC	140.458	Loss
CMGC_MAPK_JNK_MAPK9_ST	P01106	MYC	P45984	MAPK9	S71	L69F	69	Missense	proximal	-2	no	158.457	153.500	PhosphoSitePlus;EPSD	COSMIC	140.458	Down-regulation
CMGC_MAPK_JNK_MAPK9_ST	P01106	MYC	P45984	MAPK9	S71	S73P	73	Missense	proximal	2	no	158.457	158.361	PhosphoSitePlus;EPSD	COSMIC	140.458	Down-regulation
CMGC_MAPK_JNK_MAPK9_ST	P01106	MYC	P45984	MAPK9	S71	S64T	64	Missense	distal	-7	no	158.457	157.034	PhosphoSitePlus;EPSD	COSMIC	140.458	Down-regulation
CMGC_MAPK_JNK_MAPK9_ST	P01106	MYC	P45984	MAPK9	S71	R65C	65	Missense	distal	-6	no	158.457	158.090	PhosphoSitePlus;EPSD	COSMIC	140.458	Down-regulation
CMGC_MAPK_JNK_MAPK9_ST	P01106	MYC	P45984	MAPK9	S71	P72F	72	Missense	proximal	1	no	158.457	-113.548	PhosphoSitePlus;EPSD	COSMIC	140.458	Loss
CMGC_MAPK_JNK_MAPK9_ST	P01106	MYC	P45984	MAPK9	S71	P72R	72	Missense	proximal	1	no	158.457	120.869	PhosphoSitePlus;EPSD	COSMIC	140.458	Loss
CMGC_MAPK_JNK_MAPK9_ST	P01106	MYC	P45984	MAPK9	T78	S81F	81	Missense	distal	3	no	156.598	156.246	EPSD	COSMIC;CCLE	140.458	Down-regulation
CMGC_MAPK_JNK_MAPK9_ST	P01106	MYC	P45984	MAPK9	T78	R83Q	83	Missense	distal	5	no	156.598	156.807	EPSD	COSMIC	140.458	Up-regulation
CMGC_MAPK_JNK_MAPK9_ST	P01106	MYC	P45984	MAPK9	T78	A76V	76	Missense	proximal	-2	no	156.598	153.594	EPSD	COSMIC	140.458	Down-regulation
CMGC_MAPK_JNK_MAPK9_ST	P01106	MYC	P45984	MAPK9	T78	V77I	77	Missense	proximal	-1	no	156.598	156.620	EPSD	COSMIC;CCLE	140.458	Up-regulation
CMGC_MAPK_JNK_MAPK9_ST	P01106	MYC	P45984	MAPK9	T78	S71L	71	Missense	distal	-7	no	156.598	154.440	EPSD	COSMIC	140.458	Down-regulation
CMGC_MAPK_JNK_MAPK9_ST	P01106	MYC	P45984	MAPK9	T78	L82V	82	Missense	distal	4	no	156.598	156.475	EPSD	COSMIC	140.458	Down-regulation
CMGC_MAPK_JNK_MAPK9_ST	P01106	MYC	P45984	MAPK9	T78	G84R	84	Missense	distal	6	no	156.598	156.811	EPSD	COSMIC	140.458	Up-regulation
CMGC_MAPK_JNK_MAPK9_ST	P01106	MYC	P45984	MAPK9	T78	P79S	79	Missense	proximal	1	no	156.598	-124.196	EPSD	COSMIC	140.458	Loss
CMGC_MAPK_JNK_MAPK9_ST	P01106	MYC	P45984	MAPK9	T78	Y74N	74	Missense	distal	-4	no	156.598	160.924	EPSD	COSMIC;CCLE	140.458	Up-regulation
CMGC_MAPK_JNK_MAPK9_ST	P01106	MYC	P45984	MAPK9	T78	F80L	80	Missense	proximal	2	no	156.598	156.421	EPSD	COSMIC	140.458	Down-regulation
CMGC_MAPK_JNK_MAPK9_ST	P01106	MYC	P45984	MAPK9	T78	D85Y	85	Missense	distal	7	no	156.598	156.816	EPSD	COSMIC	140.458	Up-regulation
CMGC_MAPK_JNK_MAPK9_ST	P01106	MYC	P45984	MAPK9	T78	V77G	77	Missense	proximal	-1	no	156.598	156.682	EPSD	COSMIC	140.458	Up-regulation
CMGC_MAPK_JNK_MAPK9_ST	P01106	MYC	P45984	MAPK9	T78	S81C	81	Missense	distal	3	no	156.598	156.462	EPSD	COSMIC	140.458	Down-regulation
CMGC_MAPK_JNK_MAPK9_ST	P01106	MYC	P45984	MAPK9	T78	Y74H	74	Missense	distal	-4	no	156.598	157.667	EPSD	COSMIC	140.458	Up-regulation
CMGC_MAPK_JNK_MAPK9_ST	P01106	MYC	P45984	MAPK9	T78	D85E	85	Missense	distal	7	no	156.598	155.918	EPSD	COSMIC	140.458	Down-regulation
CMGC_MAPK_JNK_MAPK9_ST	P01106	MYC	P45984	MAPK9	T78	V75I	75	Missense	distal	-3	no	156.598	156.260	EPSD	COSMIC	140.458	Down-regulation
CMGC_MAPK_JNK_MAPK9_ST	P01106	MYC	P45984	MAPK9	T78	S71W	71	Missense	distal	-7	no	156.598	153.553	EPSD	COSMIC	140.458	Down-regulation
CMGC_MAPK_JNK_MAPK9_ST	P01106	MYC	P45984	MAPK9	T78	L82H	82	Missense	distal	4	no	156.598	156.492	EPSD	COSMIC	140.458	Down-regulation
CMGC_MAPK_JNK_MAPK9_ST	P01106	MYC	P45984	MAPK9	T78	S73P	73	Missense	distal	-5	no	156.598	156.618	EPSD	COSMIC	140.458	Up-regulation
CMGC_MAPK_JNK_MAPK9_ST	P01106	MYC	P45984	MAPK9	T78	P72F	72	Missense	distal	-6	no	156.598	155.808	EPSD	COSMIC	140.458	Down-regulation
CMGC_MAPK_JNK_MAPK9_ST	P01106	MYC	P45984	MAPK9	T78	P72R	72	Missense	distal	-6	no	156.598	156.710	EPSD	COSMIC	140.458	Up-regulation
CMGC_MAPK_JNK_MAPK9_ST	P01106	MYC	P45984	MAPK9	S161	K157T	157	Missense	distal	-4	no	150.506	149.337	EPSD	COSMIC	140.458	Down-regulation
CMGC_MAPK_JNK_MAPK9_ST	P01106	MYC	P45984	MAPK9	S161	A155S	155	Missense	distal	-6	no	150.506	150.419	EPSD	COSMIC	140.458	Down-regulation
CMGC_MAPK_JNK_MAPK9_ST	P01106	MYC	P45984	MAPK9	S161	K157N	157	Missense	distal	-4	no	150.506	152.726	EPSD	COSMIC	140.458	Up-regulation
CMGC_MAPK_JNK_MAPK9_ST	P01106	MYC	P45984	MAPK9	S161	A155T	155	Missense	distal	-6	no	150.506	150.152	EPSD	COSMIC	140.458	Down-regulation
CMGC_MAPK_JNK_MAPK9_ST	P01106	MYC	P45984	MAPK9	S161	N163K	163	Missense	proximal	2	no	150.506	150.550	EPSD	COSMIC	140.458	Up-regulation
CMGC_MAPK_JNK_MAPK9_ST	P01106	MYC	P45984	MAPK9	S161	P162R	162	Missense	proximal	1	no	150.506	112.918	EPSD	COSMIC	140.458	Loss
CMGC_MAPK_JNK_MAPK9_ST	P01106	MYC	P45984	MAPK9	S161	A154T	154	Missense	distal	-7	no	150.506	147.963	EPSD	COSMIC	140.458	Down-regulation
CMGC_MAPK_JNK_MAPK9_ST	P01106	MYC	P45984	MAPK9	S161	G160D	160	Missense	proximal	-1	no	150.506	150.427	EPSD	COSMIC	140.458	Down-regulation
CMGC_MAPK_JNK_MAPK9_ST	P01106	MYC	P45984	MAPK9	S161	S159N	159	Missense	proximal	-2	no	150.506	151.619	EPSD	COSMIC	140.458	Up-regulation
CMGC_MAPK_JNK_MAPK9_ST	P01106	MYC	P45984	MAPK9	S161	A165S	165	Missense	distal	4	no	150.506	150.580	EPSD	COSMIC	140.458	Up-regulation
CMGC_MAPK_JNK_MAPK9_ST	P01106	MYC	P45984	MAPK9	S161	A165T	165	Missense	distal	4	no	150.506	150.677	EPSD	COSMIC	140.458	Up-regulation
CMGC_MAPK_JNK_MAPK9_ST	P01106	MYC	P45984	MAPK9	S161	S159T	159	Missense	proximal	-2	no	150.506	150.631	EPSD	COSMIC	140.458	Up-regulation
CMGC_MAPK_JNK_MAPK9_ST	P01106	MYC	P45984	MAPK9	S161	D158G	158	Missense	distal	-3	no	150.506	149.838	EPSD	COSMIC	140.458	Down-regulation
CMGC_MAPK_JNK_MAPK9_ST	P01106	MYC	P45984	MAPK9	S161	R166H	166	Missense	distal	5	no	150.506	151.256	EPSD	COSMIC	140.458	Up-regulation
CMGC_MAPK_JNK_MAPK9_ST	P01106	MYC	P45984	MAPK9	S161	S161N	161	Missense	central	0	yes	150.506	0.000	EPSD	COSMIC	140.458	Loss
CMGC_MAPK_JNK_MAPK9_ST	P01106	MYC	P45984	MAPK9	S161	R156G	156	Missense	distal	-5	no	150.506	150.562	EPSD	COSMIC	140.458	Up-regulation
CMGC_MAPK_JNK_MAPK9_ST	P01106	MYC	P45984	MAPK9	S161	A154G	154	Missense	distal	-7	no	150.506	149.020	EPSD	COSMIC	140.458	Down-regulation
CMGC_MAPK_JNK_MAPK9_ST	P01106	MYC	P45984	MAPK9	S161	S159R	159	Missense	proximal	-2	no	150.506	153.064	EPSD	COSMIC	140.458	Up-regulation
CMGC_MAPK_JNK_MAPK9_ST	P01106	MYC	P45984	MAPK9	S161	A165D	165	Missense	distal	4	no	150.506	150.865	EPSD	COSMIC	140.458	Up-regulation
CMGC_MAPK_JNK_MAPK9_ST	P01106	MYC	P45984	MAPK9	T173	S174T	174	Missense	proximal	1	no	-118.291	143.307	EPSD	COSMIC;CCLE	140.458	Gain
CMGC_MAPK_JNK_MAPK9_ST	P01106	MYC	P45984	MAPK9	S204	P198S	198	Missense	distal	-6	no	148.093	148.001	EPSD	COSMIC	140.458	Down-regulation
CMGC_MAPK_JNK_MAPK9_ST	P01106	MYC	P45984	MAPK9	S204	S203R	203	Missense	proximal	-1	no	148.093	148.229	EPSD	COSMIC	140.458	Up-regulation
CMGC_MAPK_JNK_MAPK9_ST	P01106	MYC	P45984	MAPK9	S204	S203N	203	Missense	proximal	-1	no	148.093	148.264	EPSD	COSMIC;CCLE	140.458	Up-regulation
CMGC_MAPK_JNK_MAPK9_ST	P01106	MYC	P45984	MAPK9	S204	Y197D	197	Missense	distal	-7	no	148.093	150.772	EPSD	COSMIC	140.458	Up-regulation
CMGC_MAPK_JNK_MAPK9_ST	P01106	MYC	P45984	MAPK9	S204	S203T	203	Missense	proximal	-1	no	148.093	147.916	EPSD	COSMIC	140.458	Down-regulation
CMGC_MAPK_JNK_MAPK9_ST	P01106	MYC	P45984	MAPK9	S204	S203I	203	Missense	proximal	-1	no	148.093	147.968	EPSD	COSMIC	140.458	Down-regulation
CMGC_MAPK_JNK_MAPK9_ST	P01106	MYC	P45984	MAPK9	S204	Q211R	211	Missense	distal	7	no	148.093	147.850	EPSD	COSMIC	140.458	Down-regulation
CMGC_MAPK_JNK_MAPK9_ST	P01106	MYC	P45984	MAPK9	S204	P205S	205	Missense	proximal	1	no	148.093	-132.701	EPSD	COSMIC	140.458	Loss
CMGC_MAPK_JNK_MAPK9_ST	P01106	MYC	P45984	MAPK9	S204	N200I	200	Missense	distal	-4	no	148.093	144.914	EPSD	COSMIC	140.458	Down-regulation
CMGC_MAPK_JNK_MAPK9_ST	P01106	MYC	P45984	MAPK9	S204	S204A	204	Missense	central	0	yes	148.093	0.000	EPSD	COSMIC	140.458	Loss
CMGC_MAPK_JNK_MAPK9_ST	P01106	MYC	P45984	MAPK9	S204	S202T	202	Missense	proximal	-2	no	148.093	148.217	EPSD	COSMIC	140.458	Up-regulation
CMGC_MAPK_JNK_MAPK9_ST	P01106	MYC	P45984	MAPK9	S204	S207P	207	Missense	distal	3	no	148.093	148.141	EPSD	COSMIC	140.458	Up-regulation
CMGC_MAPK_JNK_MAPK9_ST	P01106	MYC	P45984	MAPK9	S281	S283F	283	Missense	proximal	2	no	159.066	159.303	EPSD	COSMIC	140.458	Up-regulation
CMGC_MAPK_JNK_MAPK9_ST	P01106	MYC	P45984	MAPK9	S281	S277L	277	Missense	distal	-4	no	159.066	156.875	EPSD	COSMIC	140.458	Down-regulation
CMGC_MAPK_JNK_MAPK9_ST	P01106	MYC	P45984	MAPK9	S281	H287Q	287	Missense	distal	6	no	159.066	159.525	EPSD	COSMIC	140.458	Up-regulation
CMGC_MAPK_JNK_MAPK9_ST	P01106	MYC	P45984	MAPK9	S281	S279C	279	Missense	proximal	-2	no	159.066	159.856	EPSD	COSMIC	140.458	Up-regulation
CMGC_MAPK_JNK_MAPK9_ST	P01106	MYC	P45984	MAPK9	S281	S283Y	283	Missense	proximal	2	no	159.066	159.297	EPSD	COSMIC	140.458	Up-regulation
CMGC_MAPK_JNK_MAPK9_ST	P01106	MYC	P45984	MAPK9	S281	P282A	282	Missense	proximal	1	no	159.066	140.423	EPSD	COSMIC	140.458	Loss
CMGC_MAPK_JNK_MAPK9_ST	P01106	MYC	P45984	MAPK9	S281	G285E	285	Missense	distal	4	no	159.066	158.777	EPSD	COSMIC	140.458	Down-regulation
CMGC_MAPK_JNK_MAPK9_ST	P01106	MYC	P45984	MAPK9	S281	G280R	280	Missense	proximal	-1	no	159.066	159.265	EPSD	COSMIC	140.458	Up-regulation
CMGC_MAPK_JNK_MAPK9_ST	P01106	MYC	P45984	MAPK9	S281	G274D	274	Missense	distal	-7	no	159.066	158.900	EPSD	COSMIC	140.458	Down-regulation
CMGC_MAPK_JNK_MAPK9_ST	P01106	MYC	P45984	MAPK9	S281	S281F	281	Missense	central	0	yes	159.066	0.000	EPSD	COSMIC	140.458	Loss
CMGC_MAPK_JNK_MAPK9_ST	P01106	MYC	P45984	MAPK9	S293	S293C	293	Missense	central	0	yes	161.145	0.000	EPSD	COSMIC	140.458	Loss
CMGC_MAPK_JNK_MAPK9_ST	P01106	MYC	P45984	MAPK9	S293	C300Y	300	Missense	distal	7	no	161.145	161.655	EPSD	COSMIC	140.458	Up-regulation
CMGC_MAPK_JNK_MAPK9_ST	P01106	MYC	P45984	MAPK9	S293	P290T	290	Missense	distal	-3	no	161.145	159.272	EPSD	COSMIC	140.458	Down-regulation
CMGC_MAPK_JNK_MAPK9_ST	P01106	MYC	P45984	MAPK9	S293	H287Q	287	Missense	distal	-6	no	161.145	161.514	EPSD	COSMIC	140.458	Up-regulation
CMGC_MAPK_JNK_MAPK9_ST	P01106	MYC	P45984	MAPK9	S293	C300S	300	Missense	distal	7	no	161.145	160.895	EPSD	COSMIC	140.458	Down-regulation
CMGC_MAPK_JNK_MAPK9_ST	P01106	MYC	P45984	MAPK9	S293	L295V	295	Missense	proximal	2	no	161.145	161.141	EPSD	COSMIC	140.458	Down-regulation
CMGC_MAPK_JNK_MAPK9_ST	P01106	MYC	P45984	MAPK9	S293	P290H	290	Missense	distal	-3	no	161.145	158.439	EPSD	COSMIC	140.458	Down-regulation
CMGC_MAPK_JNK_MAPK9_ST	P01106	MYC	P45984	MAPK9	S293	L297F	297	Missense	distal	4	no	161.145	161.376	EPSD	COSMIC	140.458	Up-regulation
CMGC_MAPK_JNK_MAPK9_ST	P01106	MYC	P45984	MAPK9	S293	P290S	290	Missense	distal	-3	no	161.145	160.106	EPSD	COSMIC	140.458	Down-regulation
CMGC_MAPK_JNK_MAPK9_ST	P01106	MYC	P45984	MAPK9	S293	S293R	293	Missense	central	0	yes	161.145	0.000	EPSD	COSMIC	140.458	Loss
CMGC_MAPK_JNK_MAPK9_ST	P01106	MYC	P45984	MAPK9	S293	V296F	296	Missense	distal	3	no	161.145	160.870	EPSD	COSMIC	140.458	Down-regulation
CMGC_MAPK_JNK_MAPK9_ST	P01106	MYC	P45984	MAPK9	S344	S347F	347	Missense	distal	3	no	151.903	151.551	EPSD	COSMIC	140.458	Down-regulation
CMGC_MAPK_JNK_MAPK9_ST	P01106	MYC	P45984	MAPK9	S344	E351K	351	Missense	distal	7	no	151.903	152.154	EPSD	COSMIC	140.458	Up-regulation
CMGC_MAPK_JNK_MAPK9_ST	P01106	MYC	P45984	MAPK9	S344	S337T	337	Missense	distal	-7	no	151.903	150.480	EPSD	COSMIC	140.458	Down-regulation
CMGC_MAPK_JNK_MAPK9_ST	P01106	MYC	P45984	MAPK9	S348	S347F	347	Missense	proximal	-1	no	148.262	147.886	EPSD	COSMIC	140.458	Down-regulation
CMGC_MAPK_JNK_MAPK9_ST	P01106	MYC	P45984	MAPK9	S348	V354D	354	Missense	distal	6	no	148.262	148.246	EPSD	COSMIC	140.458	Down-regulation
CMGC_MAPK_JNK_MAPK9_ST	P01106	MYC	P45984	MAPK9	S348	E351K	351	Missense	distal	3	no	148.262	148.216	EPSD	COSMIC	140.458	Down-regulation
CMGC_MAPK_JNK_MAPK9_ST	P01106	MYC	P45984	MAPK9	S348	E352G	352	Missense	distal	4	no	148.262	148.551	EPSD	COSMIC	140.458	Up-regulation
CMGC_MAPK_JNK_MAPK9_ST	P01106	MYC	P45984	MAPK9	T400	S405T	405	Missense	distal	5	no	140.118	140.508	EPSD	COSMIC	140.458	Gain
CMGC_MAPK_JNK_MAPK9_ST	P05067	APP	P45984	MAPK9	T274	T269A	269	Missense	distal	-5	no	141.263	141.225	EPSD	COSMIC	140.458	Down-regulation
CMGC_MAPK_JNK_MAPK9_ST	P05067	APP	P45984	MAPK9	T274	T269I	269	Missense	distal	-5	no	141.263	141.312	EPSD	COSMIC	140.458	Up-regulation
CMGC_MAPK_JNK_MAPK9_ST	P05067	APP	P45984	MAPK9	T274	E281K	281	Missense	distal	7	no	141.263	141.514	EPSD	COSMIC	140.458	Up-regulation
CMGC_MAPK_JNK_MAPK9_ST	P05067	APP	P45984	MAPK9	T275	T269A	269	Missense	distal	-6	no	140.615	140.969	EPSD	COSMIC	140.458	Up-regulation
CMGC_MAPK_JNK_MAPK9_ST	P05067	APP	P45984	MAPK9	T275	T269I	269	Missense	distal	-6	no	140.615	140.647	EPSD	COSMIC	140.458	Up-regulation
CMGC_MAPK_JNK_MAPK9_ST	P05067	APP	P45984	MAPK9	T275	E281K	281	Missense	distal	6	no	140.615	140.461	EPSD	COSMIC	140.458	Down-regulation
CMGC_MAPK_JNK_MAPK9_ST	P05067	APP	P45984	MAPK9	T277	E284G	284	Missense	distal	7	no	140.603	141.067	EPSD	COSMIC	140.458	Up-regulation
CMGC_MAPK_JNK_MAPK9_ST	P05067	APP	P45984	MAPK9	T277	E281K	281	Missense	distal	4	no	140.603	140.700	EPSD	COSMIC	140.458	Up-regulation
CMGC_MAPK_JNK_MAPK9_ST	P05067	APP	P45984	MAPK9	T381	E380Q	380	Missense	proximal	-1	no	152.510	152.486	EPSD	COSMIC	140.458	Down-regulation
CMGC_MAPK_JNK_MAPK9_ST	P05067	APP	P45984	MAPK9	T381	K377R	377	Missense	distal	-4	no	152.510	153.113	EPSD	COSMIC	140.458	Up-regulation
CMGC_MAPK_JNK_MAPK9_ST	P05067	APP	P45984	MAPK9	T381	D376G	376	Missense	distal	-5	no	152.510	152.485	EPSD	COSMIC	140.458	Down-regulation
CMGC_MAPK_JNK_MAPK9_ST	P05067	APP	P45984	MAPK9	T381	G383W	383	Missense	proximal	2	no	152.510	152.660	EPSD	COSMIC	140.458	Up-regulation
CMGC_MAPK_JNK_MAPK9_ST	P05067	APP	P45984	MAPK9	T381	V375I	375	Missense	distal	-6	no	152.510	152.508	EPSD	COSMIC	140.458	Down-regulation
CMGC_MAPK_JNK_MAPK9_ST	P05067	APP	P45984	MAPK9	T381	N386S	386	Missense	distal	5	no	152.510	152.740	EPSD	COSMIC	140.458	Up-regulation
CMGC_MAPK_JNK_MAPK9_ST	P05067	APP	P45984	MAPK9	S573	N571K	571	Missense	proximal	-2	no	143.502	142.279	EPSD	COSMIC	140.458	Down-regulation
CMGC_MAPK_JNK_MAPK9_ST	P05067	APP	P45984	MAPK9	S573	D574Y	574	Missense	proximal	1	no	143.502	-159.674	EPSD	COSMIC	140.458	Loss
CMGC_MAPK_JNK_MAPK9_ST	P05067	APP	P45984	MAPK9	T598	E599D	599	Missense	proximal	1	no	140.137	145.624	EPSD	COSMIC	140.458	Gain
CMGC_MAPK_JNK_MAPK9_ST	P05067	APP	P45984	MAPK9	T743	V742L	742	Missense	proximal	-1	no	158.371	158.474	EPSD	COSMIC	140.458	Up-regulation
CMGC_MAPK_JNK_MAPK9_ST	P05067	APP	P45984	MAPK9	T743	E745K	745	Missense	proximal	2	no	158.371	158.402	EPSD	COSMIC	140.458	Up-regulation
CMGC_MAPK_JNK_MAPK9_ST	P49768	PSEN1	P45984	MAPK9	S319	E318G	318	Missense	proximal	-1	no	148.450	148.277	EPSD;PhosphoSitePlus	COSMIC	140.458	Down-regulation
CMGC_MAPK_JNK_MAPK9_ST	P49768	PSEN1	P45984	MAPK9	S319	Q325R	325	Missense	distal	6	no	148.450	148.282	EPSD;PhosphoSitePlus	COSMIC	140.458	Down-regulation
CMGC_MAPK_JNK_MAPK9_ST	P49768	PSEN1	P45984	MAPK9	S319	Y315C	315	Missense	distal	-4	no	148.450	150.188	EPSD;PhosphoSitePlus	COSMIC	140.458	Up-regulation
CMGC_MAPK_JNK_MAPK9_ST	P49768	PSEN1	P45984	MAPK9	S319	E323Q	323	Missense	distal	4	no	148.450	148.429	EPSD;PhosphoSitePlus	COSMIC	140.458	Down-regulation
CMGC_MAPK_JNK_MAPK9_ST	P49768	PSEN1	P45984	MAPK9	T320	E318G	318	Missense	proximal	-2	no	150.247	148.182	PhosphoSitePlus;EPSD	COSMIC	140.458	Down-regulation
CMGC_MAPK_JNK_MAPK9_ST	P49768	PSEN1	P45984	MAPK9	T320	Q325R	325	Missense	distal	5	no	150.247	150.038	PhosphoSitePlus;EPSD	COSMIC	140.458	Down-regulation
CMGC_MAPK_JNK_MAPK9_ST	P49768	PSEN1	P45984	MAPK9	T320	Y315C	315	Missense	distal	-5	no	150.247	150.153	PhosphoSitePlus;EPSD	COSMIC	140.458	Down-regulation
CMGC_MAPK_JNK_MAPK9_ST	P49768	PSEN1	P45984	MAPK9	T320	E323Q	323	Missense	distal	3	no	150.247	150.342	PhosphoSitePlus;EPSD	COSMIC	140.458	Up-regulation
CMGC_MAPK_JNK_MAPK9_ST	P49768	PSEN1	P45984	MAPK9	T354	R352H	352	Missense	proximal	-2	no	149.829	147.003	EPSD	COSMIC;CCLE	140.458	Down-regulation
CMGC_MAPK_JNK_MAPK9_ST	P49768	PSEN1	P45984	MAPK9	S366	S367T	367	Missense	proximal	1	no	-111.436	150.162	EPSD	COSMIC	140.458	Gain
CMGC_MAPK_JNK_MAPK9_ST	P38936	CDKN1A	P45984	MAPK9	T57	D62Y	62	Missense	distal	5	no	162.997	163.553	EPSD;PhosphoSitePlus	COSMIC	140.458	Up-regulation
CMGC_MAPK_JNK_MAPK9_ST	P38936	CDKN1A	P45984	MAPK9	T57	D62H	62	Missense	distal	5	no	162.997	162.951	EPSD;PhosphoSitePlus	COSMIC	140.458	Down-regulation
CMGC_MAPK_JNK_MAPK9_ST	P38936	CDKN1A	P45984	MAPK9	T57	D52V	52	Missense	distal	-5	no	162.997	162.975	EPSD;PhosphoSitePlus	COSMIC	140.458	Down-regulation
CMGC_MAPK_JNK_MAPK9_ST	P38936	CDKN1A	P45984	MAPK9	T57	T57R	57	Missense	central	0	yes	162.997	0.000	EPSD;PhosphoSitePlus	COSMIC	140.458	Loss
CMGC_MAPK_JNK_MAPK9_ST	P38936	CDKN1A	P45984	MAPK9	S98	T97I	97	Missense	proximal	-1	no	156.917	156.969	EPSD;PhosphoSitePlus	COSMIC	140.458	Up-regulation
CMGC_MAPK_JNK_MAPK9_ST	P38936	CDKN1A	P45984	MAPK9	S130	E125Q	125	Missense	distal	-5	no	156.548	156.554	PhosphoSitePlus;EPSD	COSMIC	140.458	Up-regulation
CMGC_MAPK_JNK_MAPK9_ST	P38936	CDKN1A	P45984	MAPK9	S130	S137T	137	Missense	distal	7	no	156.548	156.842	PhosphoSitePlus;EPSD	COSMIC	140.458	Up-regulation
CMGC_MAPK_JNK_MAPK9_ST	P19793	RXRA	P45984	MAPK9	S49	P50S	50	Missense	proximal	1	no	158.363	-122.431	EPSD	COSMIC;GDSC;CCLE	140.458	Loss
CMGC_MAPK_JNK_MAPK9_ST	P19793	RXRA	P45984	MAPK9	T82	G86C	86	Missense	distal	4	no	155.980	155.916	EPSD	COSMIC	140.458	Down-regulation
CMGC_MAPK_JNK_MAPK9_ST	P19793	RXRA	P45984	MAPK9	S222	D229G	229	Missense	distal	7	no	142.947	142.731	EPSD	COSMIC	140.458	Down-regulation
CMGC_MAPK_JNK_MAPK9_ST	P19793	RXRA	P45984	MAPK9	S222	S222L	222	Missense	central	0	yes	142.947	0.000	EPSD	COSMIC	140.458	Loss
CMGC_MAPK_JNK_MAPK9_ST	P19793	RXRA	P45984	MAPK9	S225	D229G	229	Missense	distal	4	no	141.453	141.376	EPSD	COSMIC	140.458	Down-regulation
CMGC_MAPK_JNK_MAPK9_ST	P19793	RXRA	P45984	MAPK9	S225	S222L	222	Missense	distal	-3	no	141.453	140.919	EPSD	COSMIC	140.458	Down-regulation
CMGC_MAPK_JNK_MAPK9_ST	P19793	RXRA	P45984	MAPK9	T246	V250L	250	Missense	distal	4	no	141.683	141.806	EPSD	COSMIC	140.458	Up-regulation
CMGC_MAPK_JNK_MAPK9_ST	P19793	RXRA	P45984	MAPK9	T246	A241V	241	Missense	distal	-5	no	141.683	141.747	EPSD	COSMIC	140.458	Up-regulation
CMGC_MAPK_JNK_MAPK9_ST	P19793	RXRA	P45984	MAPK9	S260	M254I	254	Missense	distal	-6	no	163.067	162.639	PhosphoSitePlus	COSMIC	140.458	Down-regulation
CMGC_MAPK_JNK_MAPK9_ST	Q8WYK2	JDP2	P45984	MAPK9	T143	R136H	136	Missense	distal	-7	no	141.208	139.463	EPSD	COSMIC	140.458	Loss
CMGC_MAPK_JNK_MAPK9_ST	Q8WYK2	JDP2	P45984	MAPK9	T143	C139Y	139	Missense	distal	-4	no	141.208	139.470	EPSD	COSMIC	140.458	Loss
CMGC_MAPK_JNK_MAPK9_ST	Q8WYK2	JDP2	P45984	MAPK9	T143	D144N	144	Missense	proximal	1	no	141.208	-43.755	EPSD	COSMIC	140.458	Loss
CMGC_MAPK_JNK_MAPK9_ST	Q8WYK2	JDP2	P45984	MAPK9	T143	R136C	136	Missense	distal	-7	no	141.208	139.354	EPSD	COSMIC	140.458	Loss
CMGC_MAPK_JNK_MAPK9_ST	Q8WYK2	JDP2	P45984	MAPK9	T143	T138I	138	Missense	distal	-5	no	141.208	141.256	EPSD	COSMIC	140.458	Up-regulation
CMGC_MAPK_JNK_MAPK9_ST	Q8WYK2	JDP2	P45984	MAPK9	T148	D144N	144	Missense	distal	-4	no	154.686	156.707	PhosphoSitePlus	COSMIC	140.458	Up-regulation
CMGC_MAPK_JNK_MAPK9_ST	P50616	TOB1	P45984	MAPK9	S164	T166I	166	Missense	proximal	2	no	161.971	161.942	EPSD;PhosphoSitePlus	COSMIC	140.458	Down-regulation
CMGC_MAPK_JNK_MAPK9_ST	P50616	TOB1	P45984	MAPK9	S164	R170W	170	Missense	distal	6	no	161.971	161.374	EPSD;PhosphoSitePlus	COSMIC	140.458	Down-regulation
CMGC_MAPK_JNK_MAPK9_ST	P50616	TOB1	P45984	MAPK9	S205	L211F	211	Missense	distal	6	no	155.937	155.646	EPSD	COSMIC	140.458	Down-regulation
CMGC_MAPK_JNK_MAPK9_ST	P50616	TOB1	P45984	MAPK9	S268	P269A	269	Missense	proximal	1	no	168.357	149.713	EPSD	COSMIC	140.458	Down-regulation
CMGC_MAPK_JNK_MAPK9_ST	P50616	TOB1	P45984	MAPK9	S268	L267F	267	Missense	proximal	-1	no	168.357	168.024	EPSD	COSMIC	140.458	Down-regulation
CMGC_MAPK_JNK_MAPK9_ST	Q07817	BCL2L1	P45984	MAPK9	S62	A64T	64	Missense	proximal	2	no	156.992	157.158	EPSD;PhosphoSitePlus	COSMIC;GDSC;CCLE	140.458	Up-regulation
CMGC_MAPK_JNK_MAPK9_ST	Q07817	BCL2L1	P45984	MAPK9	S62	A60V	60	Missense	proximal	-2	no	156.992	153.988	EPSD;PhosphoSitePlus	COSMIC;GDSC;CCLE	140.458	Down-regulation
CMGC_MAPK_JNK_MAPK9_ST	Q07817	BCL2L1	P45984	MAPK9	T115	L112V	112	Missense	distal	-3	no	161.408	160.891	EPSD;PhosphoSitePlus	COSMIC	140.458	Down-regulation
CMGC_MAPK_JNK_MAPK9_ST	Q07817	BCL2L1	P45984	MAPK9	T115	G117E	117	Missense	proximal	2	no	161.408	161.276	EPSD;PhosphoSitePlus	COSMIC	140.458	Down-regulation
CMGC_MAPK_JNK_MAPK9_ST	Q07817	BCL2L1	P45984	MAPK9	T115	H113Y	113	Missense	proximal	-2	no	161.408	159.916	EPSD;PhosphoSitePlus	COSMIC	140.458	Down-regulation
CMGC_MAPK_JNK_MAPK9_ST	Q07817	BCL2L1	P45984	MAPK9	T115	A119V	119	Missense	distal	4	no	161.408	161.633	EPSD;PhosphoSitePlus	COSMIC	140.458	Up-regulation
CMGC_MAPK_JNK_MAPK9_ST	Q14934	NFATC4	P45984	MAPK9	S73	P75H	75	Missense	proximal	2	no	152.080	152.237	EPSD	COSMIC	140.458	Up-regulation
CMGC_MAPK_JNK_MAPK9_ST	Q14934	NFATC4	P45984	MAPK9	S73	P66H	66	Missense	distal	-7	no	152.080	151.946	EPSD	COSMIC	140.458	Down-regulation
CMGC_MAPK_JNK_MAPK9_ST	Q14934	NFATC4	P45984	MAPK9	S73	P66A	66	Missense	distal	-7	no	152.080	154.231	EPSD	COSMIC	140.458	Up-regulation
CMGC_MAPK_JNK_MAPK9_ST	Q14934	NFATC4	P45984	MAPK9	S73	P69L	69	Missense	distal	-4	no	152.080	150.068	EPSD	COSMIC	140.458	Down-regulation
CMGC_MAPK_JNK_MAPK9_ST	Q14934	NFATC4	P45984	MAPK9	S73	R77Q	77	Missense	distal	4	no	152.080	152.090	EPSD	COSMIC	140.458	Up-regulation
CMGC_MAPK_JNK_MAPK9_ST	Q14934	NFATC4	P45984	MAPK9	S73	P78A	78	Missense	distal	5	no	152.080	152.150	EPSD	COSMIC	140.458	Up-regulation
CMGC_MAPK_JNK_MAPK9_ST	Q14934	NFATC4	P45984	MAPK9	S73	S73L	73	Missense	central	0	yes	152.080	0.000	EPSD	COSMIC	140.458	Loss
CMGC_MAPK_JNK_MAPK9_ST	Q14934	NFATC4	P45984	MAPK9	S122	P125H	125	Missense	distal	3	no	150.164	150.002	EPSD	COSMIC	140.458	Down-regulation
CMGC_MAPK_JNK_MAPK9_ST	Q14934	NFATC4	P45984	MAPK9	S122	P128S	128	Missense	distal	6	no	150.164	150.190	EPSD	COSMIC	140.458	Up-regulation
CMGC_MAPK_JNK_MAPK9_ST	Q14934	NFATC4	P45984	MAPK9	S122	S122C	122	Missense	central	0	yes	150.164	0.000	EPSD	COSMIC	140.458	Loss
CMGC_MAPK_JNK_MAPK9_ST	Q14934	NFATC4	P45984	MAPK9	S122	S120Y	120	Missense	proximal	-2	no	150.164	148.403	EPSD	COSMIC	140.458	Down-regulation
CMGC_MAPK_JNK_MAPK9_ST	Q14934	NFATC4	P45984	MAPK9	S122	P123S	123	Missense	proximal	1	no	150.164	-130.630	EPSD	COSMIC	140.458	Loss
CMGC_MAPK_JNK_MAPK9_ST	Q14934	NFATC4	P45984	MAPK9	S122	P125Q	125	Missense	distal	3	no	150.164	150.249	EPSD	COSMIC	140.458	Up-regulation
CMGC_MAPK_JNK_MAPK9_ST	Q14934	NFATC4	P45984	MAPK9	S122	P127L	127	Missense	distal	5	no	150.164	150.932	EPSD	COSMIC	140.458	Up-regulation
CMGC_MAPK_JNK_MAPK9_ST	Q14934	NFATC4	P45984	MAPK9	S122	T124M	124	Missense	proximal	2	no	150.164	149.976	EPSD	COSMIC	140.458	Down-regulation
CMGC_MAPK_JNK_MAPK9_ST	Q14934	NFATC4	P45984	MAPK9	T124	P125H	125	Missense	proximal	1	no	155.914	-4.192	EPSD	COSMIC	140.458	Loss
CMGC_MAPK_JNK_MAPK9_ST	Q14934	NFATC4	P45984	MAPK9	T124	P128S	128	Missense	distal	4	no	155.914	156.016	EPSD	COSMIC	140.458	Up-regulation
CMGC_MAPK_JNK_MAPK9_ST	Q14934	NFATC4	P45984	MAPK9	T124	S122C	122	Missense	proximal	-2	no	155.914	156.703	EPSD	COSMIC	140.458	Up-regulation
CMGC_MAPK_JNK_MAPK9_ST	Q14934	NFATC4	P45984	MAPK9	T124	S120Y	120	Missense	distal	-4	no	155.914	152.906	EPSD	COSMIC	140.458	Down-regulation
CMGC_MAPK_JNK_MAPK9_ST	Q14934	NFATC4	P45984	MAPK9	T124	P123S	123	Missense	proximal	-1	no	155.914	155.801	EPSD	COSMIC	140.458	Down-regulation
CMGC_MAPK_JNK_MAPK9_ST	Q14934	NFATC4	P45984	MAPK9	T124	P125Q	125	Missense	proximal	1	no	155.914	135.801	EPSD	COSMIC	140.458	Loss
CMGC_MAPK_JNK_MAPK9_ST	Q14934	NFATC4	P45984	MAPK9	T124	P127L	127	Missense	distal	3	no	155.914	155.605	EPSD	COSMIC	140.458	Down-regulation
CMGC_MAPK_JNK_MAPK9_ST	Q14934	NFATC4	P45984	MAPK9	T124	A130V	130	Missense	distal	6	no	155.914	155.631	EPSD	COSMIC	140.458	Down-regulation
CMGC_MAPK_JNK_MAPK9_ST	Q14934	NFATC4	P45984	MAPK9	T124	T124M	124	Missense	central	0	yes	155.914	0.000	EPSD	COSMIC	140.458	Loss
CMGC_MAPK_JNK_MAPK9_ST	Q14934	NFATC4	P45984	MAPK9	S142	P148S	148	Missense	distal	6	no	151.322	151.349	EPSD	COSMIC	140.458	Up-regulation
CMGC_MAPK_JNK_MAPK9_ST	Q14934	NFATC4	P45984	MAPK9	S142	G141W	141	Missense	proximal	-1	no	151.322	151.043	EPSD	COSMIC	140.458	Down-regulation
CMGC_MAPK_JNK_MAPK9_ST	Q14934	NFATC4	P45984	MAPK9	S142	R144I	144	Missense	proximal	2	no	151.322	151.496	EPSD	COSMIC	140.458	Up-regulation
CMGC_MAPK_JNK_MAPK9_ST	Q14934	NFATC4	P45984	MAPK9	S142	P149Q	149	Missense	distal	7	no	151.322	151.371	EPSD	COSMIC	140.458	Up-regulation
CMGC_MAPK_JNK_MAPK9_ST	Q14934	NFATC4	P45984	MAPK9	S142	R144K	144	Missense	proximal	2	no	151.322	151.398	EPSD	COSMIC	140.458	Up-regulation
CMGC_MAPK_JNK_MAPK9_ST	Q14934	NFATC4	P45984	MAPK9	S142	W138L	138	Missense	distal	-4	no	151.322	152.760	EPSD	COSMIC	140.458	Up-regulation
CMGC_MAPK_JNK_MAPK9_ST	Q14934	NFATC4	P45984	MAPK9	S168	G163W	163	Missense	distal	-5	no	152.516	152.593	EPSD	COSMIC;GDSC;CCLE	140.458	Up-regulation
CMGC_MAPK_JNK_MAPK9_ST	Q14934	NFATC4	P45984	MAPK9	S168	S168N	168	Missense	central	0	yes	152.516	0.000	EPSD	COSMIC	140.458	Loss
CMGC_MAPK_JNK_MAPK9_ST	Q14934	NFATC4	P45984	MAPK9	S168	G163R	163	Missense	distal	-5	no	152.516	152.460	EPSD	COSMIC	140.458	Down-regulation
CMGC_MAPK_JNK_MAPK9_ST	Q14934	NFATC4	P45984	MAPK9	S168	G162V	162	Missense	distal	-6	no	152.516	152.471	EPSD	COSMIC	140.458	Down-regulation
CMGC_MAPK_JNK_MAPK9_ST	Q14934	NFATC4	P45984	MAPK9	S170	G163W	163	Missense	distal	-7	no	149.415	146.736	EPSD	COSMIC;GDSC;CCLE	140.458	Down-regulation
CMGC_MAPK_JNK_MAPK9_ST	Q14934	NFATC4	P45984	MAPK9	S170	S168N	168	Missense	proximal	-2	no	149.415	150.528	EPSD	COSMIC	140.458	Up-regulation
CMGC_MAPK_JNK_MAPK9_ST	Q14934	NFATC4	P45984	MAPK9	S170	G163R	163	Missense	distal	-7	no	149.415	150.361	EPSD	COSMIC	140.458	Up-regulation
CMGC_MAPK_JNK_MAPK9_ST	Q14934	NFATC4	P45984	MAPK9	S213	R219I	219	Missense	distal	6	no	157.977	157.682	EPSD;PhosphoSitePlus	COSMIC	140.458	Down-regulation
CMGC_MAPK_JNK_MAPK9_ST	Q14934	NFATC4	P45984	MAPK9	S213	R208C	208	Missense	distal	-5	no	157.977	158.021	EPSD;PhosphoSitePlus	COSMIC	140.458	Up-regulation
CMGC_MAPK_JNK_MAPK9_ST	Q14934	NFATC4	P45984	MAPK9	S213	S217L	217	Missense	distal	4	no	157.977	158.251	EPSD;PhosphoSitePlus	COSMIC;CCLE	140.458	Up-regulation
CMGC_MAPK_JNK_MAPK9_ST	Q14934	NFATC4	P45984	MAPK9	S213	R219Q	219	Missense	distal	6	no	157.977	158.145	EPSD;PhosphoSitePlus	COSMIC	140.458	Up-regulation
CMGC_MAPK_JNK_MAPK9_ST	Q14934	NFATC4	P45984	MAPK9	S213	S207F	207	Missense	distal	-6	no	157.977	157.279	EPSD;PhosphoSitePlus	COSMIC	140.458	Down-regulation
CMGC_MAPK_JNK_MAPK9_ST	Q14934	NFATC4	P45984	MAPK9	S213	P216L	216	Missense	distal	3	no	157.977	157.669	EPSD;PhosphoSitePlus	COSMIC	140.458	Down-regulation
CMGC_MAPK_JNK_MAPK9_ST	Q14934	NFATC4	P45984	MAPK9	S213	P214Q	214	Missense	proximal	1	no	157.977	137.865	EPSD;PhosphoSitePlus	COSMIC	140.458	Loss
CMGC_MAPK_JNK_MAPK9_ST	Q14934	NFATC4	P45984	MAPK9	S213	A206T	206	Missense	distal	-7	no	157.977	155.434	EPSD;PhosphoSitePlus	COSMIC	140.458	Down-regulation
CMGC_MAPK_JNK_MAPK9_ST	Q14934	NFATC4	P45984	MAPK9	S217	R219I	219	Missense	proximal	2	no	169.743	169.916	PhosphoSitePlus;EPSD	COSMIC	140.458	Up-regulation
CMGC_MAPK_JNK_MAPK9_ST	Q14934	NFATC4	P45984	MAPK9	S217	S217L	217	Missense	central	0	yes	169.743	0.000	PhosphoSitePlus;EPSD	COSMIC;CCLE	140.458	Loss
CMGC_MAPK_JNK_MAPK9_ST	Q14934	NFATC4	P45984	MAPK9	S217	R219Q	219	Missense	proximal	2	no	169.743	169.788	PhosphoSitePlus;EPSD	COSMIC	140.458	Up-regulation
CMGC_MAPK_JNK_MAPK9_ST	Q14934	NFATC4	P45984	MAPK9	S217	P216L	216	Missense	proximal	-1	no	169.743	169.587	PhosphoSitePlus;EPSD	COSMIC	140.458	Down-regulation
CMGC_MAPK_JNK_MAPK9_ST	Q14934	NFATC4	P45984	MAPK9	S217	P214Q	214	Missense	distal	-3	no	169.743	169.200	PhosphoSitePlus;EPSD	COSMIC	140.458	Down-regulation
CMGC_MAPK_JNK_MAPK9_ST	Q14934	NFATC4	P45984	MAPK9	S217	P224T	224	Missense	distal	7	no	169.743	170.265	PhosphoSitePlus;EPSD	COSMIC	140.458	Up-regulation
CMGC_MAPK_JNK_MAPK9_ST	Q14934	NFATC4	P45984	MAPK9	S217	R223W	223	Missense	distal	6	no	169.743	169.145	PhosphoSitePlus;EPSD	COSMIC	140.458	Down-regulation
CMGC_MAPK_JNK_MAPK9_ST	Q14934	NFATC4	P45984	MAPK9	S221	R219I	219	Missense	proximal	-2	no	153.960	152.026	EPSD	COSMIC	140.458	Down-regulation
CMGC_MAPK_JNK_MAPK9_ST	Q14934	NFATC4	P45984	MAPK9	S221	P227Q	227	Missense	distal	6	no	153.960	154.192	EPSD	COSMIC	140.458	Up-regulation
CMGC_MAPK_JNK_MAPK9_ST	Q14934	NFATC4	P45984	MAPK9	S221	P227H	227	Missense	distal	6	no	153.960	153.733	EPSD	COSMIC	140.458	Down-regulation
CMGC_MAPK_JNK_MAPK9_ST	Q14934	NFATC4	P45984	MAPK9	S221	E228K	228	Missense	distal	7	no	153.960	154.211	EPSD	COSMIC	140.458	Up-regulation
CMGC_MAPK_JNK_MAPK9_ST	Q14934	NFATC4	P45984	MAPK9	S221	S217L	217	Missense	distal	-4	no	153.960	151.769	EPSD	COSMIC;CCLE	140.458	Down-regulation
CMGC_MAPK_JNK_MAPK9_ST	Q14934	NFATC4	P45984	MAPK9	S221	R219Q	219	Missense	proximal	-2	no	153.960	153.962	EPSD	COSMIC	140.458	Up-regulation
CMGC_MAPK_JNK_MAPK9_ST	Q14934	NFATC4	P45984	MAPK9	S221	P216L	216	Missense	distal	-5	no	153.960	154.060	EPSD	COSMIC	140.458	Up-regulation
CMGC_MAPK_JNK_MAPK9_ST	Q14934	NFATC4	P45984	MAPK9	S221	P214Q	214	Missense	distal	-7	no	153.960	155.499	EPSD	COSMIC	140.458	Up-regulation
CMGC_MAPK_JNK_MAPK9_ST	Q14934	NFATC4	P45984	MAPK9	S221	P224T	224	Missense	distal	3	no	153.960	153.798	EPSD	COSMIC	140.458	Down-regulation
CMGC_MAPK_JNK_MAPK9_ST	Q14934	NFATC4	P45984	MAPK9	S221	R223W	223	Missense	proximal	2	no	153.960	154.287	EPSD	COSMIC	140.458	Up-regulation
CMGC_MAPK_JNK_MAPK9_ST	Q14934	NFATC4	P45984	MAPK9	S221	T226S	226	Missense	distal	5	no	153.960	153.570	EPSD	COSMIC	140.458	Down-regulation
CMGC_MAPK_JNK_MAPK9_ST	Q14934	NFATC4	P45984	MAPK9	T226	R219I	219	Missense	distal	-7	no	161.694	160.240	EPSD	COSMIC	140.458	Down-regulation
CMGC_MAPK_JNK_MAPK9_ST	Q14934	NFATC4	P45984	MAPK9	T226	P227Q	227	Missense	proximal	1	no	161.694	141.581	EPSD	COSMIC	140.458	Down-regulation
CMGC_MAPK_JNK_MAPK9_ST	Q14934	NFATC4	P45984	MAPK9	T226	P227H	227	Missense	proximal	1	no	161.694	1.588	EPSD	COSMIC	140.458	Loss
CMGC_MAPK_JNK_MAPK9_ST	Q14934	NFATC4	P45984	MAPK9	T226	E228K	228	Missense	proximal	2	no	161.694	161.724	EPSD	COSMIC	140.458	Up-regulation
CMGC_MAPK_JNK_MAPK9_ST	Q14934	NFATC4	P45984	MAPK9	T226	R219Q	219	Missense	distal	-7	no	161.694	161.621	EPSD	COSMIC	140.458	Down-regulation
CMGC_MAPK_JNK_MAPK9_ST	Q14934	NFATC4	P45984	MAPK9	T226	P224T	224	Missense	proximal	-2	no	161.694	158.057	EPSD	COSMIC	140.458	Down-regulation
CMGC_MAPK_JNK_MAPK9_ST	Q14934	NFATC4	P45984	MAPK9	T226	R223W	223	Missense	distal	-3	no	161.694	157.826	EPSD	COSMIC	140.458	Down-regulation
CMGC_MAPK_JNK_MAPK9_ST	Q14934	NFATC4	P45984	MAPK9	T226	W231S	231	Missense	distal	5	no	161.694	160.574	EPSD	COSMIC	140.458	Down-regulation
CMGC_MAPK_JNK_MAPK9_ST	Q14934	NFATC4	P45984	MAPK9	S237	G235S	235	Missense	proximal	-2	no	153.704	153.810	EPSD	COSMIC	140.458	Up-regulation
CMGC_MAPK_JNK_MAPK9_ST	Q14934	NFATC4	P45984	MAPK9	S237	R241L	241	Missense	distal	4	no	153.704	154.090	EPSD	COSMIC	140.458	Up-regulation
CMGC_MAPK_JNK_MAPK9_ST	Q14934	NFATC4	P45984	MAPK9	S237	R241Q	241	Missense	distal	4	no	153.704	153.713	EPSD	COSMIC	140.458	Up-regulation
CMGC_MAPK_JNK_MAPK9_ST	Q14934	NFATC4	P45984	MAPK9	S237	W231S	231	Missense	distal	-6	no	153.704	154.306	EPSD	COSMIC	140.458	Up-regulation
CMGC_MAPK_JNK_MAPK9_ST	Q14934	NFATC4	P45984	MAPK9	T256	P257S	257	Missense	proximal	1	no	149.655	-131.139	EPSD	COSMIC	140.458	Loss
CMGC_MAPK_JNK_MAPK9_ST	Q14934	NFATC4	P45984	MAPK9	T256	R261W	261	Missense	distal	5	no	149.655	151.006	EPSD	COSMIC	140.458	Up-regulation
CMGC_MAPK_JNK_MAPK9_ST	Q14934	NFATC4	P45984	MAPK9	T256	P253L	253	Missense	distal	-3	no	149.655	148.082	EPSD	COSMIC	140.458	Down-regulation
CMGC_MAPK_JNK_MAPK9_ST	Q14934	NFATC4	P45984	MAPK9	T256	R261Q	261	Missense	distal	5	no	149.655	149.864	EPSD	COSMIC	140.458	Up-regulation
CMGC_MAPK_JNK_MAPK9_ST	Q14934	NFATC4	P45984	MAPK9	T256	S259F	259	Missense	distal	3	no	149.655	149.303	EPSD	COSMIC	140.458	Down-regulation
CMGC_MAPK_JNK_MAPK9_ST	Q14934	NFATC4	P45984	MAPK9	S259	P257S	257	Missense	proximal	-2	no	155.524	151.763	EPSD	COSMIC	140.458	Down-regulation
CMGC_MAPK_JNK_MAPK9_ST	Q14934	NFATC4	P45984	MAPK9	S259	R261W	261	Missense	proximal	2	no	155.524	155.851	EPSD	COSMIC	140.458	Up-regulation
CMGC_MAPK_JNK_MAPK9_ST	Q14934	NFATC4	P45984	MAPK9	S259	P253L	253	Missense	distal	-6	no	155.524	155.082	EPSD	COSMIC	140.458	Down-regulation
CMGC_MAPK_JNK_MAPK9_ST	Q14934	NFATC4	P45984	MAPK9	S259	P260Q	260	Missense	proximal	1	no	155.524	135.412	EPSD	COSMIC	140.458	Loss
CMGC_MAPK_JNK_MAPK9_ST	Q14934	NFATC4	P45984	MAPK9	S259	R261Q	261	Missense	proximal	2	no	155.524	155.569	EPSD	COSMIC	140.458	Up-regulation
CMGC_MAPK_JNK_MAPK9_ST	Q14934	NFATC4	P45984	MAPK9	S259	P265L	265	Missense	distal	6	no	155.524	155.291	EPSD	COSMIC	140.458	Down-regulation
CMGC_MAPK_JNK_MAPK9_ST	Q14934	NFATC4	P45984	MAPK9	S259	S259F	259	Missense	central	0	yes	155.524	0.000	EPSD	COSMIC	140.458	Loss
CMGC_MAPK_JNK_MAPK9_ST	Q14934	NFATC4	P45984	MAPK9	S264	P257S	257	Missense	distal	-7	no	156.327	157.358	EPSD	COSMIC	140.458	Up-regulation
CMGC_MAPK_JNK_MAPK9_ST	Q14934	NFATC4	P45984	MAPK9	S264	R261W	261	Missense	distal	-3	no	156.327	152.459	EPSD	COSMIC	140.458	Down-regulation
CMGC_MAPK_JNK_MAPK9_ST	Q14934	NFATC4	P45984	MAPK9	S264	P260Q	260	Missense	distal	-4	no	156.327	157.638	EPSD	COSMIC	140.458	Up-regulation
CMGC_MAPK_JNK_MAPK9_ST	Q14934	NFATC4	P45984	MAPK9	S264	R261Q	261	Missense	distal	-3	no	156.327	156.104	EPSD	COSMIC	140.458	Down-regulation
CMGC_MAPK_JNK_MAPK9_ST	Q14934	NFATC4	P45984	MAPK9	S264	P265L	265	Missense	proximal	1	no	156.327	111.424	EPSD	COSMIC	140.458	Loss
CMGC_MAPK_JNK_MAPK9_ST	Q14934	NFATC4	P45984	MAPK9	S264	Y271H	271	Missense	distal	7	no	156.327	155.741	EPSD	COSMIC	140.458	Down-regulation
CMGC_MAPK_JNK_MAPK9_ST	Q14934	NFATC4	P45984	MAPK9	S264	R269Q	269	Missense	distal	5	no	156.327	156.536	EPSD	COSMIC	140.458	Up-regulation
CMGC_MAPK_JNK_MAPK9_ST	Q14934	NFATC4	P45984	MAPK9	S264	R269W	269	Missense	distal	5	no	156.327	157.678	EPSD	COSMIC	140.458	Up-regulation
CMGC_MAPK_JNK_MAPK9_ST	Q14934	NFATC4	P45984	MAPK9	S264	R270H	270	Missense	distal	6	no	156.327	156.036	EPSD	COSMIC	140.458	Down-regulation
CMGC_MAPK_JNK_MAPK9_ST	Q14934	NFATC4	P45984	MAPK9	S264	R270C	270	Missense	distal	6	no	156.327	156.153	EPSD	COSMIC	140.458	Down-regulation
CMGC_MAPK_JNK_MAPK9_ST	Q14934	NFATC4	P45984	MAPK9	S264	S259F	259	Missense	distal	-5	no	156.327	156.470	EPSD	COSMIC	140.458	Up-regulation
CMGC_MAPK_JNK_MAPK9_ST	Q14934	NFATC4	P45984	MAPK9	T276	P277Q	277	Missense	proximal	1	no	157.707	137.595	EPSD	COSMIC	140.458	Loss
CMGC_MAPK_JNK_MAPK9_ST	Q14934	NFATC4	P45984	MAPK9	T276	S272F	272	Missense	distal	-4	no	157.707	154.425	EPSD	COSMIC	140.458	Down-regulation
CMGC_MAPK_JNK_MAPK9_ST	Q14934	NFATC4	P45984	MAPK9	T276	G275S	275	Missense	proximal	-1	no	157.707	157.769	EPSD	COSMIC	140.458	Up-regulation
CMGC_MAPK_JNK_MAPK9_ST	Q14934	NFATC4	P45984	MAPK9	T276	S273L	273	Missense	distal	-3	no	157.707	157.173	EPSD	COSMIC	140.458	Down-regulation
CMGC_MAPK_JNK_MAPK9_ST	Q14934	NFATC4	P45984	MAPK9	T276	P282A	282	Missense	distal	6	no	157.707	157.870	EPSD	COSMIC	140.458	Up-regulation
CMGC_MAPK_JNK_MAPK9_ST	Q14934	NFATC4	P45984	MAPK9	T276	Y271H	271	Missense	distal	-5	no	157.707	157.626	EPSD	COSMIC	140.458	Down-regulation
CMGC_MAPK_JNK_MAPK9_ST	Q14934	NFATC4	P45984	MAPK9	T276	R269Q	269	Missense	distal	-7	no	157.707	157.635	EPSD	COSMIC	140.458	Down-regulation
CMGC_MAPK_JNK_MAPK9_ST	Q14934	NFATC4	P45984	MAPK9	T276	S272P	272	Missense	distal	-4	no	157.707	157.528	EPSD	COSMIC	140.458	Down-regulation
CMGC_MAPK_JNK_MAPK9_ST	Q14934	NFATC4	P45984	MAPK9	T276	R269W	269	Missense	distal	-7	no	157.707	154.082	EPSD	COSMIC	140.458	Down-regulation
CMGC_MAPK_JNK_MAPK9_ST	Q14934	NFATC4	P45984	MAPK9	T276	S281F	281	Missense	distal	5	no	157.707	158.895	EPSD	COSMIC	140.458	Up-regulation
CMGC_MAPK_JNK_MAPK9_ST	Q14934	NFATC4	P45984	MAPK9	T276	R270H	270	Missense	distal	-6	no	157.707	157.266	EPSD	COSMIC	140.458	Down-regulation
CMGC_MAPK_JNK_MAPK9_ST	Q14934	NFATC4	P45984	MAPK9	T276	R270C	270	Missense	distal	-6	no	157.707	157.341	EPSD	COSMIC	140.458	Down-regulation
CMGC_MAPK_JNK_MAPK9_ST	Q14934	NFATC4	P45984	MAPK9	T276	S274L	274	Missense	proximal	-2	no	157.707	160.394	EPSD	COSMIC	140.458	Up-regulation
CMGC_MAPK_JNK_MAPK9_ST	Q14934	NFATC4	P45984	MAPK9	S279	R286W	286	Missense	distal	7	no	141.744	142.859	EPSD	COSMIC	140.458	Up-regulation
CMGC_MAPK_JNK_MAPK9_ST	Q14934	NFATC4	P45984	MAPK9	S279	P277Q	277	Missense	proximal	-2	no	141.744	140.544	EPSD	COSMIC	140.458	Down-regulation
CMGC_MAPK_JNK_MAPK9_ST	Q14934	NFATC4	P45984	MAPK9	S279	S272F	272	Missense	distal	-7	no	141.744	138.806	EPSD	COSMIC	140.458	Loss
CMGC_MAPK_JNK_MAPK9_ST	Q14934	NFATC4	P45984	MAPK9	S279	S285P	285	Missense	distal	6	no	141.744	141.718	EPSD	COSMIC	140.458	Down-regulation
CMGC_MAPK_JNK_MAPK9_ST	Q14934	NFATC4	P45984	MAPK9	S279	G275S	275	Missense	distal	-4	no	141.744	143.278	EPSD	COSMIC	140.458	Up-regulation
CMGC_MAPK_JNK_MAPK9_ST	Q14934	NFATC4	P45984	MAPK9	S279	S273L	273	Missense	distal	-6	no	141.744	141.394	EPSD	COSMIC	140.458	Down-regulation
CMGC_MAPK_JNK_MAPK9_ST	Q14934	NFATC4	P45984	MAPK9	S279	P282A	282	Missense	distal	3	no	141.744	141.794	EPSD	COSMIC	140.458	Up-regulation
CMGC_MAPK_JNK_MAPK9_ST	Q14934	NFATC4	P45984	MAPK9	S279	R286H	286	Missense	distal	7	no	141.744	142.342	EPSD	COSMIC	140.458	Up-regulation
CMGC_MAPK_JNK_MAPK9_ST	Q14934	NFATC4	P45984	MAPK9	S279	S272P	272	Missense	distal	-7	no	141.744	140.713	EPSD	COSMIC	140.458	Down-regulation
CMGC_MAPK_JNK_MAPK9_ST	Q14934	NFATC4	P45984	MAPK9	S279	S281F	281	Missense	proximal	2	no	141.744	141.981	EPSD	COSMIC	140.458	Up-regulation
CMGC_MAPK_JNK_MAPK9_ST	Q14934	NFATC4	P45984	MAPK9	S279	S274L	274	Missense	distal	-5	no	141.744	141.864	EPSD	COSMIC	140.458	Up-regulation
CMGC_MAPK_JNK_MAPK9_ST	Q14934	NFATC4	P45984	MAPK9	S281	R286W	286	Missense	distal	5	no	155.428	156.779	EPSD	COSMIC	140.458	Up-regulation
CMGC_MAPK_JNK_MAPK9_ST	Q14934	NFATC4	P45984	MAPK9	S281	P277Q	277	Missense	distal	-4	no	155.428	156.739	EPSD	COSMIC	140.458	Up-regulation
CMGC_MAPK_JNK_MAPK9_ST	Q14934	NFATC4	P45984	MAPK9	S281	S285P	285	Missense	distal	4	no	155.428	155.326	EPSD	COSMIC	140.458	Down-regulation
CMGC_MAPK_JNK_MAPK9_ST	Q14934	NFATC4	P45984	MAPK9	S281	G275S	275	Missense	distal	-6	no	155.428	155.616	EPSD	COSMIC	140.458	Up-regulation
CMGC_MAPK_JNK_MAPK9_ST	Q14934	NFATC4	P45984	MAPK9	S281	G288W	288	Missense	distal	7	no	155.428	155.793	EPSD	COSMIC	140.458	Up-regulation
CMGC_MAPK_JNK_MAPK9_ST	Q14934	NFATC4	P45984	MAPK9	S281	P282A	282	Missense	proximal	1	no	155.428	136.784	EPSD	COSMIC	140.458	Loss
CMGC_MAPK_JNK_MAPK9_ST	Q14934	NFATC4	P45984	MAPK9	S281	R286H	286	Missense	distal	5	no	155.428	156.178	EPSD	COSMIC	140.458	Up-regulation
CMGC_MAPK_JNK_MAPK9_ST	Q14934	NFATC4	P45984	MAPK9	S281	R287H	287	Missense	distal	6	no	155.428	155.137	EPSD	COSMIC	140.458	Down-regulation
CMGC_MAPK_JNK_MAPK9_ST	Q14934	NFATC4	P45984	MAPK9	S281	R287S	287	Missense	distal	6	no	155.428	155.391	EPSD	COSMIC	140.458	Down-regulation
CMGC_MAPK_JNK_MAPK9_ST	Q14934	NFATC4	P45984	MAPK9	S281	S281F	281	Missense	central	0	yes	155.428	0.000	EPSD	COSMIC	140.458	Loss
CMGC_MAPK_JNK_MAPK9_ST	Q14934	NFATC4	P45984	MAPK9	S281	S274L	274	Missense	distal	-7	no	155.428	153.269	EPSD	COSMIC	140.458	Down-regulation
CMGC_MAPK_JNK_MAPK9_ST	Q14934	NFATC4	P45984	MAPK9	S311	P314S	314	Missense	distal	3	no	163.567	163.520	EPSD	COSMIC	140.458	Down-regulation
CMGC_MAPK_JNK_MAPK9_ST	Q14934	NFATC4	P45984	MAPK9	S311	P312S	312	Missense	proximal	1	no	163.567	-117.227	EPSD	COSMIC	140.458	Loss
CMGC_MAPK_JNK_MAPK9_ST	Q14934	NFATC4	P45984	MAPK9	S311	P304L	304	Missense	distal	-7	no	163.567	162.440	EPSD	COSMIC	140.458	Down-regulation
CMGC_MAPK_JNK_MAPK9_ST	Q14934	NFATC4	P45984	MAPK9	S311	D316Y	316	Missense	distal	5	no	163.567	164.124	EPSD	COSMIC	140.458	Up-regulation
CMGC_MAPK_JNK_MAPK9_ST	Q14934	NFATC4	P45984	MAPK9	S311	F315L	315	Missense	distal	4	no	163.567	163.336	EPSD	COSMIC;CCLE	140.458	Down-regulation
CMGC_MAPK_JNK_MAPK9_ST	Q14934	NFATC4	P45984	MAPK9	S334	S335P	335	Missense	proximal	1	no	-127.443	153.351	EPSD	COSMIC	140.458	Gain
CMGC_MAPK_JNK_MAPK9_ST	Q14934	NFATC4	P45984	MAPK9	S344	S344F	344	Missense	central	0	yes	142.061	0.000	EPSD	COSMIC	140.458	Loss
CMGC_MAPK_JNK_MAPK9_ST	Q14934	NFATC4	P45984	MAPK9	S344	P342A	342	Missense	proximal	-2	no	142.061	140.791	EPSD	COSMIC	140.458	Down-regulation
CMGC_MAPK_JNK_MAPK9_ST	Q14934	NFATC4	P45984	MAPK9	S344	R343Q	343	Missense	proximal	-1	no	142.061	142.013	EPSD	COSMIC	140.458	Down-regulation
CMGC_MAPK_JNK_MAPK9_ST	Q14934	NFATC4	P45984	MAPK9	S382	D376N	376	Missense	distal	-6	no	157.845	158.358	EPSD	COSMIC	140.458	Up-regulation
CMGC_MAPK_JNK_MAPK9_ST	Q14934	NFATC4	P45984	MAPK9	S382	V380A	380	Missense	proximal	-2	no	157.845	160.849	EPSD	COSMIC	140.458	Up-regulation
CMGC_MAPK_JNK_MAPK9_ST	Q14934	NFATC4	P45984	MAPK9	S382	P383T	383	Missense	proximal	1	no	157.845	138.649	EPSD	COSMIC	140.458	Loss
CMGC_MAPK_JNK_MAPK9_ST	Q14934	NFATC4	P45984	MAPK9	S382	S387F	387	Missense	distal	5	no	157.845	159.033	EPSD	COSMIC	140.458	Up-regulation
CMGC_MAPK_JNK_MAPK9_ST	Q14934	NFATC4	P45984	MAPK9	S382	D376Y	376	Missense	distal	-6	no	157.845	157.573	EPSD	COSMIC	140.458	Down-regulation
CMGC_MAPK_JNK_MAPK9_ST	Q14934	NFATC4	P45984	MAPK9	S395	P396T	396	Missense	proximal	1	no	145.228	126.033	EPSD	COSMIC	140.458	Loss
CMGC_MAPK_JNK_MAPK9_ST	Q14934	NFATC4	P45984	MAPK9	S395	A402V	402	Missense	distal	7	no	145.228	145.902	EPSD	COSMIC	140.458	Up-regulation
CMGC_MAPK_JNK_MAPK9_ST	Q14934	NFATC4	P45984	MAPK9	S395	R399K	399	Missense	distal	4	no	145.228	145.357	EPSD	COSMIC	140.458	Up-regulation
CMGC_MAPK_JNK_MAPK9_ST	Q14934	NFATC4	P45984	MAPK9	S395	G392V	392	Missense	distal	-3	no	145.228	145.443	EPSD	COSMIC	140.458	Up-regulation
CMGC_MAPK_JNK_MAPK9_ST	Q14934	NFATC4	P45984	MAPK9	S395	F398S	398	Missense	distal	3	no	145.228	145.581	EPSD	COSMIC	140.458	Up-regulation
CMGC_MAPK_JNK_MAPK9_ST	Q14934	NFATC4	P45984	MAPK9	S395	I391T	391	Missense	distal	-4	no	145.228	145.018	EPSD	COSMIC	140.458	Down-regulation
CMGC_MAPK_JNK_MAPK9_ST	Q14934	NFATC4	P45984	MAPK9	S395	S395I	395	Missense	central	0	yes	145.228	0.000	EPSD	COSMIC	140.458	Loss
CMGC_MAPK_JNK_MAPK9_ST	Q14934	NFATC4	P45984	MAPK9	S532	L527I	527	Missense	distal	-5	no	145.970	145.945	EPSD	COSMIC	140.458	Down-regulation
CMGC_MAPK_JNK_MAPK9_ST	Q14934	NFATC4	P45984	MAPK9	S532	R537M	537	Missense	distal	5	no	145.970	146.120	EPSD	COSMIC	140.458	Up-regulation
CMGC_MAPK_JNK_MAPK9_ST	Q14934	NFATC4	P45984	MAPK9	S532	R530Q	530	Missense	proximal	-2	no	145.970	145.972	EPSD	COSMIC	140.458	Up-regulation
CMGC_MAPK_JNK_MAPK9_ST	Q14934	NFATC4	P45984	MAPK9	S532	G525R	525	Missense	distal	-7	no	145.970	146.917	EPSD	COSMIC	140.458	Up-regulation
CMGC_MAPK_JNK_MAPK9_ST	Q14934	NFATC4	P45984	MAPK9	S532	R530W	530	Missense	proximal	-2	no	145.970	141.911	EPSD	COSMIC	140.458	Down-regulation
CMGC_MAPK_JNK_MAPK9_ST	Q14934	NFATC4	P45984	MAPK9	S532	E535K	535	Missense	distal	3	no	145.970	145.924	EPSD	COSMIC	140.458	Down-regulation
CMGC_MAPK_JNK_MAPK9_ST	Q14934	NFATC4	P45984	MAPK9	S532	R537Q	537	Missense	distal	5	no	145.970	146.179	EPSD	COSMIC	140.458	Up-regulation
CMGC_MAPK_JNK_MAPK9_ST	Q14934	NFATC4	P45984	MAPK9	S592	E589K	589	Missense	distal	-3	no	161.627	160.352	EPSD	COSMIC	140.458	Down-regulation
CMGC_MAPK_JNK_MAPK9_ST	Q14934	NFATC4	P45984	MAPK9	S592	S594L	594	Missense	proximal	2	no	161.627	161.686	EPSD	COSMIC	140.458	Up-regulation
CMGC_MAPK_JNK_MAPK9_ST	Q14934	NFATC4	P45984	MAPK9	S592	P586H	586	Missense	distal	-6	no	161.627	161.297	EPSD	COSMIC	140.458	Down-regulation
CMGC_MAPK_JNK_MAPK9_ST	Q14934	NFATC4	P45984	MAPK9	S592	P593S	593	Missense	proximal	1	no	161.627	-119.167	EPSD	COSMIC	140.458	Loss
CMGC_MAPK_JNK_MAPK9_ST	Q14934	NFATC4	P45984	MAPK9	S592	R599I	599	Missense	distal	7	no	161.627	162.279	EPSD	COSMIC	140.458	Up-regulation
CMGC_MAPK_JNK_MAPK9_ST	Q14934	NFATC4	P45984	MAPK9	S592	S594R	594	Missense	proximal	2	no	161.627	161.505	EPSD	COSMIC	140.458	Down-regulation
CMGC_MAPK_JNK_MAPK9_ST	Q14934	NFATC4	P45984	MAPK9	S676	P677A	677	Missense	proximal	1	no	148.132	129.488	EPSD	COSMIC	140.458	Loss
CMGC_MAPK_JNK_MAPK9_ST	Q14934	NFATC4	P45984	MAPK9	S676	S676N	676	Missense	central	0	yes	148.132	0.000	EPSD	COSMIC	140.458	Loss
CMGC_MAPK_JNK_MAPK9_ST	Q14934	NFATC4	P45984	MAPK9	S676	G671W	671	Missense	distal	-5	no	148.132	148.209	EPSD	COSMIC	140.458	Up-regulation
CMGC_MAPK_JNK_MAPK9_ST	Q14934	NFATC4	P45984	MAPK9	S676	R675H	675	Missense	proximal	-1	no	148.132	147.864	EPSD	COSMIC;CCLE	140.458	Down-regulation
CMGC_MAPK_JNK_MAPK9_ST	Q14934	NFATC4	P45984	MAPK9	S676	R672W	672	Missense	distal	-4	no	148.132	144.802	EPSD	COSMIC	140.458	Down-regulation
CMGC_MAPK_JNK_MAPK9_ST	Q14934	NFATC4	P45984	MAPK9	S676	S669A	669	Missense	distal	-7	no	148.132	149.252	EPSD	COSMIC	140.458	Up-regulation
CMGC_MAPK_JNK_MAPK9_ST	Q14934	NFATC4	P45984	MAPK9	S676	G671R	671	Missense	distal	-5	no	148.132	148.076	EPSD	COSMIC	140.458	Down-regulation
CMGC_MAPK_JNK_MAPK9_ST	Q14934	NFATC4	P45984	MAPK9	S676	F683C	683	Missense	distal	7	no	148.132	147.587	EPSD	COSMIC	140.458	Down-regulation
CMGC_MAPK_JNK_MAPK9_ST	Q14934	NFATC4	P45984	MAPK9	S676	R675C	675	Missense	proximal	-1	no	148.132	147.950	EPSD	COSMIC	140.458	Down-regulation
CMGC_MAPK_JNK_MAPK9_ST	Q14934	NFATC4	P45984	MAPK9	S716	P723L	723	Missense	distal	7	no	152.457	153.096	EPSD	COSMIC	140.458	Up-regulation
CMGC_MAPK_JNK_MAPK9_ST	Q14934	NFATC4	P45984	MAPK9	S716	P721H	721	Missense	distal	5	no	152.457	153.033	EPSD	COSMIC	140.458	Up-regulation
CMGC_MAPK_JNK_MAPK9_ST	Q14934	NFATC4	P45984	MAPK9	S716	F709C	709	Missense	distal	-7	no	152.457	154.121	EPSD	COSMIC	140.458	Up-regulation
CMGC_MAPK_JNK_MAPK9_ST	Q14934	NFATC4	P45984	MAPK9	S716	R719K	719	Missense	distal	3	no	152.457	152.291	EPSD	COSMIC	140.458	Down-regulation
CMGC_MAPK_JNK_MAPK9_ST	Q14934	NFATC4	P45984	MAPK9	S716	P723S	723	Missense	distal	7	no	152.457	152.685	EPSD	COSMIC	140.458	Up-regulation
CMGC_MAPK_JNK_MAPK9_ST	Q14934	NFATC4	P45984	MAPK9	S819	G824C	824	Missense	distal	5	no	163.760	163.571	EPSD	COSMIC;CCLE	140.458	Down-regulation
CMGC_MAPK_JNK_MAPK9_ST	Q14934	NFATC4	P45984	MAPK9	S819	P817S	817	Missense	proximal	-2	no	163.760	159.999	EPSD	COSMIC	140.458	Down-regulation
CMGC_MAPK_JNK_MAPK9_ST	Q14934	NFATC4	P45984	MAPK9	S819	P820A	820	Missense	proximal	1	no	163.760	145.116	EPSD	COSMIC	140.458	Down-regulation
CMGC_MAPK_JNK_MAPK9_ST	Q14934	NFATC4	P45984	MAPK9	S819	S819F	819	Missense	central	0	yes	163.760	0.000	EPSD	COSMIC	140.458	Loss
CMGC_MAPK_JNK_MAPK9_ST	Q14934	NFATC4	P45984	MAPK9	S819	A818V	818	Missense	proximal	-1	no	163.760	163.531	EPSD	COSMIC	140.458	Down-regulation
CMGC_MAPK_JNK_MAPK9_ST	Q14934	NFATC4	P45984	MAPK9	S819	A818S	818	Missense	proximal	-1	no	163.760	163.677	EPSD	COSMIC	140.458	Down-regulation
CMGC_MAPK_JNK_MAPK9_ST	Q14934	NFATC4	P45984	MAPK9	S819	P825S	825	Missense	distal	6	no	163.760	163.786	EPSD	COSMIC	140.458	Up-regulation
CMGC_MAPK_JNK_MAPK9_ST	Q14934	NFATC4	P45984	MAPK9	S819	P815H	815	Missense	distal	-4	no	163.760	162.000	EPSD	COSMIC	140.458	Down-regulation
CMGC_MAPK_JNK_MAPK9_ST	Q14934	NFATC4	P45984	MAPK9	S819	P813S	813	Missense	distal	-6	no	163.760	163.668	EPSD	COSMIC	140.458	Down-regulation
CMGC_MAPK_JNK_MAPK9_ST	Q14934	NFATC4	P45984	MAPK9	S819	E823A	823	Missense	distal	4	no	163.760	163.768	EPSD	COSMIC	140.458	Up-regulation
CMGC_MAPK_JNK_MAPK9_ST	Q14934	NFATC4	P45984	MAPK9	S819	R812W	812	Missense	distal	-7	no	163.760	160.134	EPSD	COSMIC	140.458	Down-regulation
CMGC_MAPK_JNK_MAPK9_ST	Q14934	NFATC4	P45984	MAPK9	S819	F826Y	826	Missense	distal	7	no	163.760	163.724	EPSD	COSMIC	140.458	Down-regulation
CMGC_MAPK_JNK_MAPK9_ST	Q14934	NFATC4	P45984	MAPK9	S819	P815S	815	Missense	distal	-4	no	163.760	163.939	EPSD	COSMIC	140.458	Up-regulation
CMGC_MAPK_JNK_MAPK9_ST	P52945	PDX1	P45984	MAPK9	S31	P33L	33	Missense	proximal	2	no	144.434	144.589	EPSD	COSMIC;CCLE	140.458	Up-regulation
CMGC_MAPK_JNK_MAPK9_ST	P52945	PDX1	P45984	MAPK9	S31	P33T	33	Missense	proximal	2	no	144.434	144.611	EPSD	COSMIC	140.458	Up-regulation
CMGC_MAPK_JNK_MAPK9_ST	P52945	PDX1	P45984	MAPK9	S31	P33H	33	Missense	proximal	2	no	144.434	144.591	EPSD	COSMIC	140.458	Up-regulation
CMGC_MAPK_JNK_MAPK9_ST	P52945	PDX1	P45984	MAPK9	S266	S266R	266	Missense	central	0	yes	141.867	0.000	EPSD	COSMIC;CCLE	140.458	Loss
CMGC_MAPK_JNK_MAPK9_ST	P52945	PDX1	P45984	MAPK9	S268	S266R	266	Missense	proximal	-2	no	154.251	156.809	EPSD	COSMIC;CCLE	140.458	Up-regulation
CMGC_MAPK_JNK_MAPK9_ST	Q9UGP4	LIMD1	P45984	MAPK9	S187	W190R	190	Missense	distal	3	no	148.491	148.992	EPSD	COSMIC	140.458	Up-regulation
CMGC_MAPK_JNK_MAPK9_ST	Q9UGP4	LIMD1	P45984	MAPK9	S197	S197F	197	Missense	central	0	yes	146.722	0.000	EPSD	COSMIC	140.458	Loss
CMGC_MAPK_JNK_MAPK9_ST	Q9UGP4	LIMD1	P45984	MAPK9	S197	W190R	190	Missense	distal	-7	no	146.722	150.348	EPSD	COSMIC	140.458	Up-regulation
CMGC_MAPK_JNK_MAPK9_ST	Q9UGP4	LIMD1	P45984	MAPK9	S197	S199R	199	Missense	proximal	2	no	146.722	146.601	EPSD	COSMIC	140.458	Down-regulation
CMGC_MAPK_JNK_MAPK9_ST	Q9UGP4	LIMD1	P45984	MAPK9	S211	P209L	209	Missense	proximal	-2	no	151.619	150.544	EPSD	COSMIC	140.458	Down-regulation
CMGC_MAPK_JNK_MAPK9_ST	Q9UGP4	LIMD1	P45984	MAPK9	S240	S236F	236	Missense	distal	-4	no	141.668	138.386	EPSD	COSMIC	140.458	Loss
CMGC_MAPK_JNK_MAPK9_ST	Q9UGP4	LIMD1	P45984	MAPK9	T294	V287L	287	Missense	distal	-7	no	159.787	158.590	EPSD	COSMIC	140.458	Down-regulation
CMGC_MAPK_JNK_MAPK9_ST	Q9UGP4	LIMD1	P45984	MAPK9	S298	A302T	302	Missense	distal	4	no	142.141	142.312	EPSD	COSMIC	140.458	Up-regulation
CMGC_MAPK_JNK_MAPK9_ST	Q9UGP4	LIMD1	P45984	MAPK9	S353	G359S	359	Missense	distal	6	no	153.938	154.114	EPSD	COSMIC;GDSC;CCLE	140.458	Up-regulation
CMGC_MAPK_JNK_MAPK9_ST	Q9UGP4	LIMD1	P45984	MAPK9	S353	G356D	356	Missense	distal	3	no	153.938	153.987	EPSD	COSMIC;GDSC;CCLE	140.458	Up-regulation
CMGC_MAPK_JNK_MAPK9_ST	Q9UGP4	LIMD1	P45984	MAPK9	T375	G378D	378	Missense	distal	3	no	140.658	140.707	EPSD	COSMIC;GDSC;CCLE	140.458	Up-regulation
CMGC_MAPK_JNK_MAPK9_ST	Q9UGP4	LIMD1	P45984	MAPK9	S384	G378D	378	Missense	distal	-6	no	154.677	154.458	EPSD	COSMIC;GDSC;CCLE	140.458	Down-regulation
CMGC_MAPK_JNK_MAPK9_ST	Q9UGP4	LIMD1	P45984	MAPK9	S421	S424F	424	Missense	distal	3	no	148.618	148.266	EPSD;PhosphoSitePlus	COSMIC	140.458	Down-regulation
CMGC_MAPK_JNK_MAPK9_ST	Q9UGP4	LIMD1	P45984	MAPK9	S421	G415R	415	Missense	distal	-6	no	148.618	149.010	EPSD;PhosphoSitePlus	COSMIC;GDSC	140.458	Up-regulation
CMGC_MAPK_JNK_MAPK9_ST	Q9UGP4	LIMD1	P45984	MAPK9	S424	S424F	424	Missense	central	0	yes	154.717	0.000	EPSD;PhosphoSitePlus	COSMIC	140.458	Loss
CMGC_MAPK_JNK_MAPK9_ST	Q12968	NFATC3	P45984	MAPK9	S98	G102D	102	Missense	distal	4	no	154.151	154.229	EPSD	COSMIC	140.458	Up-regulation
CMGC_MAPK_JNK_MAPK9_ST	Q12968	NFATC3	P45984	MAPK9	S98	E94A	94	Missense	distal	-4	no	154.151	154.490	EPSD	COSMIC	140.458	Up-regulation
CMGC_MAPK_JNK_MAPK9_ST	Q12968	NFATC3	P45984	MAPK9	S117	I116L	116	Missense	proximal	-1	no	151.515	151.596	EPSD	COSMIC;GDSC;CCLE	140.458	Up-regulation
CMGC_MAPK_JNK_MAPK9_ST	Q12968	NFATC3	P45984	MAPK9	S117	S117Y	117	Missense	central	0	yes	151.515	0.000	EPSD	COSMIC	140.458	Loss
CMGC_MAPK_JNK_MAPK9_ST	Q12968	NFATC3	P45984	MAPK9	S163	P166S	166	Missense	distal	3	no	158.558	158.510	EPSD;PhosphoSitePlus	COSMIC	140.458	Down-regulation
CMGC_MAPK_JNK_MAPK9_ST	Q12968	NFATC3	P45984	MAPK9	S163	S161Y	161	Missense	proximal	-2	no	158.558	156.797	EPSD;PhosphoSitePlus	COSMIC	140.458	Down-regulation
CMGC_MAPK_JNK_MAPK9_ST	Q12968	NFATC3	P45984	MAPK9	S165	P166S	166	Missense	proximal	1	no	161.917	-118.877	PhosphoSitePlus;EPSD	COSMIC	140.458	Loss
CMGC_MAPK_JNK_MAPK9_ST	Q12968	NFATC3	P45984	MAPK9	S165	S161Y	161	Missense	distal	-4	no	161.917	158.909	PhosphoSitePlus;EPSD	COSMIC	140.458	Down-regulation
CMGC_MAPK_JNK_MAPK9_ST	Q12968	NFATC3	P45984	MAPK9	S236	S240F	240	Missense	distal	4	no	143.131	143.636	EPSD	COSMIC;GDSC;CCLE	140.458	Up-regulation
CMGC_MAPK_JNK_MAPK9_ST	Q12968	NFATC3	P45984	MAPK9	S240	R246S	246	Missense	distal	6	no	154.988	154.951	EPSD	COSMIC;GDSC;CCLE	140.458	Down-regulation
CMGC_MAPK_JNK_MAPK9_ST	Q12968	NFATC3	P45984	MAPK9	S240	S240F	240	Missense	central	0	yes	154.988	0.000	EPSD	COSMIC;GDSC;CCLE	140.458	Loss
CMGC_MAPK_JNK_MAPK9_ST	Q12968	NFATC3	P45984	MAPK9	S244	R246S	246	Missense	proximal	2	no	144.008	144.129	EPSD	COSMIC;GDSC;CCLE	140.458	Up-regulation
CMGC_MAPK_JNK_MAPK9_ST	Q12968	NFATC3	P45984	MAPK9	S244	S240F	240	Missense	distal	-4	no	144.008	140.725	EPSD	COSMIC;GDSC;CCLE	140.458	Down-regulation
CMGC_MAPK_JNK_MAPK9_ST	Q12968	NFATC3	P45984	MAPK9	S269	S269Y	269	Missense	central	0	yes	162.521	0.000	EPSD	COSMIC	140.458	Loss
CMGC_MAPK_JNK_MAPK9_ST	Q12968	NFATC3	P45984	MAPK9	S269	T268I	268	Missense	proximal	-1	no	162.521	162.573	EPSD	COSMIC	140.458	Up-regulation
CMGC_MAPK_JNK_MAPK9_ST	Q12968	NFATC3	P45984	MAPK9	S288	L287V	287	Missense	proximal	-1	no	160.939	160.836	EPSD	COSMIC	140.458	Down-regulation
CMGC_MAPK_JNK_MAPK9_ST	Q12968	NFATC3	P45984	MAPK9	S288	P295S	295	Missense	distal	7	no	160.939	161.167	EPSD	COSMIC	140.458	Up-regulation
CMGC_MAPK_JNK_MAPK9_ST	Q12968	NFATC3	P45984	MAPK9	S288	Y283N	283	Missense	distal	-5	no	160.939	160.765	EPSD	COSMIC	140.458	Down-regulation
CMGC_MAPK_JNK_MAPK9_ST	Q12968	NFATC3	P45984	MAPK9	S292	P297S	297	Missense	distal	5	no	152.425	152.483	EPSD	COSMIC	140.458	Up-regulation
CMGC_MAPK_JNK_MAPK9_ST	Q12968	NFATC3	P45984	MAPK9	S292	L287V	287	Missense	distal	-5	no	152.425	152.377	EPSD	COSMIC	140.458	Down-regulation
CMGC_MAPK_JNK_MAPK9_ST	Q12968	NFATC3	P45984	MAPK9	S292	P295S	295	Missense	distal	3	no	152.425	152.377	EPSD	COSMIC	140.458	Down-regulation
CMGC_MAPK_JNK_MAPK9_ST	Q12968	NFATC3	P45984	MAPK9	S296	P297S	297	Missense	proximal	1	no	155.850	-124.944	EPSD	COSMIC	140.458	Loss
CMGC_MAPK_JNK_MAPK9_ST	Q12968	NFATC3	P45984	MAPK9	S296	P295S	295	Missense	proximal	-1	no	155.850	155.737	EPSD	COSMIC	140.458	Down-regulation
CMGC_MAPK_JNK_MAPK9_ST	Q12968	NFATC3	P45984	MAPK9	S300	P297S	297	Missense	distal	-3	no	147.967	146.928	EPSD	COSMIC	140.458	Down-regulation
CMGC_MAPK_JNK_MAPK9_ST	Q12968	NFATC3	P45984	MAPK9	S300	P295S	295	Missense	distal	-5	no	147.967	147.947	EPSD	COSMIC	140.458	Down-regulation
CMGC_MAPK_JNK_MAPK9_ST	Q12968	NFATC3	P45984	MAPK9	S366	S359L	359	Missense	distal	-7	no	154.406	152.248	EPSD	COSMIC	140.458	Down-regulation
CMGC_MAPK_JNK_MAPK9_ST	Q12968	NFATC3	P45984	MAPK9	S366	R369L	369	Missense	distal	3	no	154.406	153.989	EPSD	COSMIC	140.458	Down-regulation
CMGC_MAPK_JNK_MAPK9_ST	Q12968	NFATC3	P45984	MAPK9	S397	P396S	396	Missense	proximal	-1	no	150.482	150.369	EPSD	COSMIC	140.458	Down-regulation
CMGC_MAPK_JNK_MAPK9_ST	Q12968	NFATC3	P45984	MAPK9	S397	D390N	390	Missense	distal	-7	no	150.482	152.900	EPSD	COSMIC	140.458	Up-regulation
CMGC_MAPK_JNK_MAPK9_ST	Q12968	NFATC3	P45984	MAPK9	T409	S415P	415	Missense	distal	6	no	155.812	155.785	EPSD	COSMIC	140.458	Down-regulation
CMGC_MAPK_JNK_MAPK9_ST	Q12968	NFATC3	P45984	MAPK9	T409	K405R	405	Missense	distal	-4	no	155.812	156.414	EPSD	COSMIC	140.458	Up-regulation
CMGC_MAPK_JNK_MAPK9_ST	Q12968	NFATC3	P45984	MAPK9	T409	S415F	415	Missense	distal	6	no	155.812	155.262	EPSD	COSMIC	140.458	Down-regulation
CMGC_MAPK_JNK_MAPK9_ST	Q12968	NFATC3	P45984	MAPK9	T409	R413H	413	Missense	distal	4	no	155.812	156.092	EPSD	COSMIC	140.458	Up-regulation
CMGC_MAPK_JNK_MAPK9_ST	Q12968	NFATC3	P45984	MAPK9	T414	S415P	415	Missense	proximal	1	no	-131.543	149.251	EPSD	COSMIC	140.458	Gain
CMGC_MAPK_JNK_MAPK9_ST	Q12968	NFATC3	P45984	MAPK9	S546	D547N	547	Missense	proximal	1	no	144.036	-40.927	EPSD	COSMIC	140.458	Loss
CMGC_MAPK_JNK_MAPK9_ST	Q12968	NFATC3	P45984	MAPK9	S546	L543R	543	Missense	distal	-3	no	144.036	145.288	EPSD	COSMIC	140.458	Up-regulation
CMGC_MAPK_JNK_MAPK9_ST	Q12968	NFATC3	P45984	MAPK9	S546	K552N	552	Missense	distal	6	no	144.036	144.380	EPSD	COSMIC	140.458	Up-regulation
CMGC_MAPK_JNK_MAPK9_ST	Q12968	NFATC3	P45984	MAPK9	T698	R694C	694	Missense	distal	-4	no	147.737	146.765	EPSD	COSMIC	140.458	Down-regulation
CMGC_MAPK_JNK_MAPK9_ST	Q12968	NFATC3	P45984	MAPK9	T698	Q704R	704	Missense	distal	6	no	147.737	147.569	EPSD	COSMIC	140.458	Down-regulation
CMGC_MAPK_JNK_MAPK9_ST	Q12968	NFATC3	P45984	MAPK9	S1072	D1073Y	1073	Missense	proximal	1	no	141.347	-161.829	EPSD	COSMIC	140.458	Loss
CMGC_MAPK_JNK_MAPK9_ST	Q12968	NFATC3	P45984	MAPK9	S1072	D1073N	1073	Missense	proximal	1	no	141.347	-43.616	EPSD	COSMIC	140.458	Loss
CMGC_MAPK_JNK_MAPK9_ST	P05412	JUN	P45984	MAPK9	S63	K56N	56	Missense	distal	-7	no	156.619	158.055	EPSD;PhosphoSitePlus	COSMIC	140.458	Up-regulation
CMGC_MAPK_JNK_MAPK9_ST	P05412	JUN	P45984	MAPK9	S63	L61F	61	Missense	proximal	-2	no	156.619	151.662	EPSD;PhosphoSitePlus	COSMIC	140.458	Down-regulation
CMGC_MAPK_JNK_MAPK9_ST	P05412	JUN	P45984	MAPK9	S73	R78H	78	Missense	distal	5	no	158.505	159.255	PhosphoSitePlus;EPSD	COSMIC	140.458	Up-regulation
CMGC_MAPK_JNK_MAPK9_ST	P05412	JUN	P45984	MAPK9	T91	P92Q	92	Missense	proximal	1	no	158.955	138.843	EPSD	COSMIC	140.458	Loss
CMGC_MAPK_JNK_MAPK9_ST	P05412	JUN	P45984	MAPK9	T91	L98M	98	Missense	distal	7	no	158.955	158.485	EPSD	COSMIC	140.458	Down-regulation
CMGC_MAPK_JNK_MAPK9_ST	P05412	JUN	P45984	MAPK9	T91	P94S	94	Missense	distal	3	no	158.955	158.908	EPSD	COSMIC	140.458	Down-regulation
CMGC_MAPK_JNK_MAPK9_ST	P05412	JUN	P45984	MAPK9	T93	P100L	100	Missense	distal	7	no	155.827	156.467	EPSD	COSMIC	140.458	Up-regulation
CMGC_MAPK_JNK_MAPK9_ST	P05412	JUN	P45984	MAPK9	T93	P92Q	92	Missense	proximal	-1	no	155.827	155.802	EPSD	COSMIC	140.458	Down-regulation
CMGC_MAPK_JNK_MAPK9_ST	P05412	JUN	P45984	MAPK9	T93	L98M	98	Missense	distal	5	no	155.827	155.035	EPSD	COSMIC	140.458	Down-regulation
CMGC_MAPK_JNK_MAPK9_ST	P05412	JUN	P45984	MAPK9	T93	P94S	94	Missense	proximal	1	no	155.827	-124.967	EPSD	COSMIC	140.458	Loss
CMGC_MAPK_JNK_MAPK9_ST	P05412	JUN	P45984	MAPK9	T239	P240Q	240	Missense	proximal	1	no	156.287	136.175	EPSD	COSMIC	140.458	Loss
CMGC_MAPK_JNK_MAPK9_ST	P05412	JUN	P45984	MAPK9	T239	T239I	239	Missense	central	0	yes	156.287	0.000	EPSD	COSMIC	140.458	Loss
CMGC_MAPK_JNK_MAPK9_ST	P05412	JUN	P45984	MAPK9	S243	P240Q	240	Missense	distal	-3	no	157.732	157.189	EPSD	COSMIC	140.458	Down-regulation
CMGC_MAPK_JNK_MAPK9_ST	P05412	JUN	P45984	MAPK9	S243	T239I	239	Missense	distal	-4	no	157.732	157.942	EPSD	COSMIC	140.458	Up-regulation
CMGC_MAPK_JNK_MAPK9_ST	P05412	JUN	P45984	MAPK9	S296	E293K	293	Missense	distal	-3	no	141.410	140.135	EPSD	COSMIC	140.458	Loss
CMGC_MAPK_JNK_MAPK9_ST	P05412	JUN	P45984	MAPK9	S296	E293Q	293	Missense	distal	-3	no	141.410	141.713	EPSD	COSMIC	140.458	Up-regulation
CMGC_MAPK_JNK_MAPK9_ST	P05412	JUN	P45984	MAPK9	S296	T297M	297	Missense	proximal	1	no	141.410	96.386	EPSD	COSMIC	140.458	Loss
CMGC_MAPK_JNK_MAPK9_ST	P05412	JUN	P45984	MAPK9	S296	M300I	300	Missense	distal	4	no	141.410	141.739	EPSD	COSMIC	140.458	Up-regulation
CMGC_MAPK_JNK_MAPK9_ST	P04637	TP53	P45984	MAPK9	S15	E11Q	11	Missense	distal	-4	no	140.584	141.500	EPSD	COSMIC;GDSC;CCLE	140.458	Up-regulation
CMGC_MAPK_JNK_MAPK9_ST	P04637	TP53	P45984	MAPK9	S15	S20L	20	Missense	distal	5	no	140.584	141.295	EPSD	COSMIC	140.458	Up-regulation
CMGC_MAPK_JNK_MAPK9_ST	P04637	TP53	P45984	MAPK9	S15	Q16L	16	Missense	proximal	1	no	140.584	115.794	EPSD	COSMIC;GDSC;CCLE	140.458	Loss
CMGC_MAPK_JNK_MAPK9_ST	P04637	TP53	P45984	MAPK9	S15	P13S	13	Missense	proximal	-2	no	140.584	136.823	EPSD	COSMIC	140.458	Loss
CMGC_MAPK_JNK_MAPK9_ST	P04637	TP53	P45984	MAPK9	S15	E17K	17	Missense	proximal	2	no	140.584	140.615	EPSD	COSMIC	140.458	Up-regulation
CMGC_MAPK_JNK_MAPK9_ST	P04637	TP53	P45984	MAPK9	S15	V10I	10	Missense	distal	-5	no	140.584	140.607	EPSD	COSMIC	140.458	Up-regulation
CMGC_MAPK_JNK_MAPK9_ST	P04637	TP53	P45984	MAPK9	S15	P8L	8	Missense	distal	-7	no	140.584	139.457	EPSD	COSMIC	140.458	Loss
CMGC_MAPK_JNK_MAPK9_ST	P04637	TP53	P45984	MAPK9	S15	P8S	8	Missense	distal	-7	no	140.584	141.615	EPSD	COSMIC	140.458	Up-regulation
CMGC_MAPK_JNK_MAPK9_ST	P04637	TP53	P45984	MAPK9	S15	P13L	13	Missense	proximal	-2	no	140.584	139.510	EPSD	COSMIC	140.458	Loss
CMGC_MAPK_JNK_MAPK9_ST	P04637	TP53	P45984	MAPK9	S15	V10G	10	Missense	distal	-5	no	140.584	140.580	EPSD	COSMIC	140.458	Down-regulation
CMGC_MAPK_JNK_MAPK9_ST	P04637	TP53	P45984	MAPK9	S15	T18A	18	Missense	distal	3	no	140.584	140.795	EPSD	COSMIC	140.458	Up-regulation
CMGC_MAPK_JNK_MAPK9_ST	P04637	TP53	P45984	MAPK9	S15	F19S	19	Missense	distal	4	no	140.584	140.079	EPSD	COSMIC	140.458	Loss
CMGC_MAPK_JNK_MAPK9_ST	P04637	TP53	P45984	MAPK9	S15	E17V	17	Missense	proximal	2	no	140.584	140.716	EPSD	COSMIC	140.458	Up-regulation
CMGC_MAPK_JNK_MAPK9_ST	P04637	TP53	P45984	MAPK9	S15	S9G	9	Missense	distal	-6	no	140.584	140.396	EPSD	COSMIC	140.458	Loss
CMGC_MAPK_JNK_MAPK9_ST	P04637	TP53	P45984	MAPK9	S15	T18I	18	Missense	distal	3	no	140.584	140.583	EPSD	COSMIC	140.458	Down-regulation
CMGC_MAPK_JNK_MAPK9_ST	P04637	TP53	P45984	MAPK9	S15	T18K	18	Missense	distal	3	no	140.584	140.689	EPSD	COSMIC	140.458	Up-regulation
CMGC_MAPK_JNK_MAPK9_ST	P04637	TP53	P45984	MAPK9	S15	T18R	18	Missense	distal	3	no	140.584	140.855	EPSD	COSMIC	140.458	Up-regulation
CMGC_MAPK_JNK_MAPK9_ST	P04637	TP53	P45984	MAPK9	S15	S15I	15	Missense	central	0	yes	140.584	0.000	EPSD	COSMIC	140.458	Loss
CMGC_MAPK_JNK_MAPK9_ST	P04637	TP53	P45984	MAPK9	S20	S20L	20	Missense	central	0	yes	147.780	0.000	EPSD;PhosphoSitePlus	COSMIC	140.458	Loss
CMGC_MAPK_JNK_MAPK9_ST	P04637	TP53	P45984	MAPK9	S20	Q16L	16	Missense	distal	-4	no	147.780	144.457	EPSD;PhosphoSitePlus	COSMIC;GDSC;CCLE	140.458	Down-regulation
CMGC_MAPK_JNK_MAPK9_ST	P04637	TP53	P45984	MAPK9	S20	P13S	13	Missense	distal	-7	no	147.780	148.811	EPSD;PhosphoSitePlus	COSMIC	140.458	Up-regulation
CMGC_MAPK_JNK_MAPK9_ST	P04637	TP53	P45984	MAPK9	S20	E17K	17	Missense	distal	-3	no	147.780	146.505	EPSD;PhosphoSitePlus	COSMIC	140.458	Down-regulation
CMGC_MAPK_JNK_MAPK9_ST	P04637	TP53	P45984	MAPK9	S20	P13L	13	Missense	distal	-7	no	147.780	146.652	EPSD;PhosphoSitePlus	COSMIC	140.458	Down-regulation
CMGC_MAPK_JNK_MAPK9_ST	P04637	TP53	P45984	MAPK9	S20	L26P	26	Missense	distal	6	no	147.780	148.012	EPSD;PhosphoSitePlus	COSMIC	140.458	Up-regulation
CMGC_MAPK_JNK_MAPK9_ST	P04637	TP53	P45984	MAPK9	S20	T18A	18	Missense	proximal	-2	no	147.780	150.146	EPSD;PhosphoSitePlus	COSMIC	140.458	Up-regulation
CMGC_MAPK_JNK_MAPK9_ST	P04637	TP53	P45984	MAPK9	S20	F19S	19	Missense	proximal	-1	no	147.780	148.155	EPSD;PhosphoSitePlus	COSMIC	140.458	Up-regulation
CMGC_MAPK_JNK_MAPK9_ST	P04637	TP53	P45984	MAPK9	S20	E17V	17	Missense	distal	-3	no	147.780	146.536	EPSD;PhosphoSitePlus	COSMIC	140.458	Down-regulation
CMGC_MAPK_JNK_MAPK9_ST	P04637	TP53	P45984	MAPK9	S20	P27T	27	Missense	distal	7	no	147.780	148.302	EPSD;PhosphoSitePlus	COSMIC	140.458	Up-regulation
CMGC_MAPK_JNK_MAPK9_ST	P04637	TP53	P45984	MAPK9	S20	T18I	18	Missense	proximal	-2	no	147.780	148.279	EPSD;PhosphoSitePlus	COSMIC	140.458	Up-regulation
CMGC_MAPK_JNK_MAPK9_ST	P04637	TP53	P45984	MAPK9	S20	T18K	18	Missense	proximal	-2	no	147.780	147.545	EPSD;PhosphoSitePlus	COSMIC	140.458	Down-regulation
CMGC_MAPK_JNK_MAPK9_ST	P04637	TP53	P45984	MAPK9	S20	T18R	18	Missense	proximal	-2	no	147.780	150.213	EPSD;PhosphoSitePlus	COSMIC	140.458	Up-regulation
CMGC_MAPK_JNK_MAPK9_ST	P04637	TP53	P45984	MAPK9	S20	S15I	15	Missense	distal	-5	no	147.780	147.874	EPSD;PhosphoSitePlus	COSMIC	140.458	Up-regulation
CMGC_MAPK_JNK_MAPK9_ST	P04637	TP53	P45984	MAPK9	S33	M40I	40	Missense	distal	7	no	154.719	155.008	EPSD	COSMIC	140.458	Up-regulation
CMGC_MAPK_JNK_MAPK9_ST	P04637	TP53	P45984	MAPK9	S33	V31I	31	Missense	proximal	-2	no	154.719	155.857	EPSD	COSMIC;GDSC;CCLE	140.458	Up-regulation
CMGC_MAPK_JNK_MAPK9_ST	P04637	TP53	P45984	MAPK9	S33	P36L	36	Missense	distal	3	no	154.719	154.410	EPSD	COSMIC;GDSC;CCLE	140.458	Down-regulation
CMGC_MAPK_JNK_MAPK9_ST	P04637	TP53	P45984	MAPK9	S33	L35F	35	Missense	proximal	2	no	154.719	154.896	EPSD	COSMIC	140.458	Up-regulation
CMGC_MAPK_JNK_MAPK9_ST	P04637	TP53	P45984	MAPK9	S33	Q38L	38	Missense	distal	5	no	154.719	155.452	EPSD	COSMIC	140.458	Up-regulation
CMGC_MAPK_JNK_MAPK9_ST	P04637	TP53	P45984	MAPK9	S33	S37T	37	Missense	distal	4	no	154.719	154.816	EPSD	COSMIC	140.458	Up-regulation
CMGC_MAPK_JNK_MAPK9_ST	P04637	TP53	P45984	MAPK9	S33	L26P	26	Missense	distal	-7	no	154.719	155.846	EPSD	COSMIC	140.458	Up-regulation
CMGC_MAPK_JNK_MAPK9_ST	P04637	TP53	P45984	MAPK9	S33	P36S	36	Missense	distal	3	no	154.719	154.671	EPSD	COSMIC;GDSC;CCLE	140.458	Down-regulation
CMGC_MAPK_JNK_MAPK9_ST	P04637	TP53	P45984	MAPK9	S33	A39V	39	Missense	distal	6	no	154.719	154.436	EPSD	COSMIC	140.458	Down-regulation
CMGC_MAPK_JNK_MAPK9_ST	P04637	TP53	P45984	MAPK9	S33	A39S	39	Missense	distal	6	no	154.719	154.582	EPSD	COSMIC	140.458	Down-regulation
CMGC_MAPK_JNK_MAPK9_ST	P04637	TP53	P45984	MAPK9	S33	N30K	30	Missense	distal	-3	no	154.719	152.982	EPSD	COSMIC	140.458	Down-regulation
CMGC_MAPK_JNK_MAPK9_ST	P04637	TP53	P45984	MAPK9	S33	A39T	39	Missense	distal	6	no	154.719	154.306	EPSD	COSMIC	140.458	Down-regulation
CMGC_MAPK_JNK_MAPK9_ST	P04637	TP53	P45984	MAPK9	S33	P27T	27	Missense	distal	-6	no	154.719	154.359	EPSD	COSMIC	140.458	Down-regulation
CMGC_MAPK_JNK_MAPK9_ST	P04637	TP53	P45984	MAPK9	S33	P36R	36	Missense	distal	3	no	154.719	154.827	EPSD	COSMIC	140.458	Up-regulation
CMGC_MAPK_JNK_MAPK9_ST	P04637	TP53	P45984	MAPK9	S33	L35R	35	Missense	proximal	2	no	154.719	154.538	EPSD	COSMIC	140.458	Down-regulation
CMGC_MAPK_JNK_MAPK9_ST	P04637	TP53	P45984	MAPK9	S33	L35H	35	Missense	proximal	2	no	154.719	154.721	EPSD	COSMIC	140.458	Up-regulation
CMGC_MAPK_JNK_MAPK9_ST	P04637	TP53	P45984	MAPK9	S33	L35P	35	Missense	proximal	2	no	154.719	154.564	EPSD	COSMIC	140.458	Down-regulation
CMGC_MAPK_JNK_MAPK9_ST	P04637	TP53	P45984	MAPK9	S33	L35I	35	Missense	proximal	2	no	154.719	154.711	EPSD	COSMIC	140.458	Down-regulation
CMGC_MAPK_JNK_MAPK9_ST	P04637	TP53	P45984	MAPK9	S33	L35V	35	Missense	proximal	2	no	154.719	154.715	EPSD	COSMIC	140.458	Down-regulation
CMGC_MAPK_JNK_MAPK9_ST	P04637	TP53	P45984	MAPK9	S37	M40I	40	Missense	distal	3	no	140.751	140.575	EPSD	COSMIC	140.458	Down-regulation
CMGC_MAPK_JNK_MAPK9_ST	P04637	TP53	P45984	MAPK9	S37	V31I	31	Missense	distal	-6	no	140.751	140.749	EPSD	COSMIC;GDSC;CCLE	140.458	Down-regulation
CMGC_MAPK_JNK_MAPK9_ST	P04637	TP53	P45984	MAPK9	S37	P36L	36	Missense	proximal	-1	no	140.751	140.596	EPSD	COSMIC;GDSC;CCLE	140.458	Down-regulation
CMGC_MAPK_JNK_MAPK9_ST	P04637	TP53	P45984	MAPK9	S37	S33T	33	Missense	distal	-4	no	140.751	138.681	EPSD	COSMIC	140.458	Loss
CMGC_MAPK_JNK_MAPK9_ST	P04637	TP53	P45984	MAPK9	S37	D41N	41	Missense	distal	4	no	140.751	140.433	EPSD	COSMIC	140.458	Loss
CMGC_MAPK_JNK_MAPK9_ST	P04637	TP53	P45984	MAPK9	S37	L35F	35	Missense	proximal	-2	no	140.751	135.795	EPSD	COSMIC	140.458	Loss
CMGC_MAPK_JNK_MAPK9_ST	P04637	TP53	P45984	MAPK9	S37	Q38L	38	Missense	proximal	1	no	140.751	115.961	EPSD	COSMIC	140.458	Loss
CMGC_MAPK_JNK_MAPK9_ST	P04637	TP53	P45984	MAPK9	S37	M44I	44	Missense	distal	7	no	140.751	141.040	EPSD	COSMIC	140.458	Up-regulation
CMGC_MAPK_JNK_MAPK9_ST	P04637	TP53	P45984	MAPK9	S37	P36S	36	Missense	proximal	-1	no	140.751	140.639	EPSD	COSMIC;GDSC;CCLE	140.458	Down-regulation
CMGC_MAPK_JNK_MAPK9_ST	P04637	TP53	P45984	MAPK9	S37	A39V	39	Missense	proximal	2	no	140.751	140.892	EPSD	COSMIC	140.458	Up-regulation
CMGC_MAPK_JNK_MAPK9_ST	P04637	TP53	P45984	MAPK9	S37	A39S	39	Missense	proximal	2	no	140.751	140.836	EPSD	COSMIC	140.458	Up-regulation
CMGC_MAPK_JNK_MAPK9_ST	P04637	TP53	P45984	MAPK9	S37	D42Y	42	Missense	distal	5	no	140.751	141.308	EPSD	COSMIC	140.458	Up-regulation
CMGC_MAPK_JNK_MAPK9_ST	P04637	TP53	P45984	MAPK9	S37	M44R	44	Missense	distal	7	no	140.751	140.388	EPSD	COSMIC	140.458	Loss
CMGC_MAPK_JNK_MAPK9_ST	P04637	TP53	P45984	MAPK9	S37	M44V	44	Missense	distal	7	no	140.751	141.180	EPSD	COSMIC	140.458	Up-regulation
CMGC_MAPK_JNK_MAPK9_ST	P04637	TP53	P45984	MAPK9	S37	N30K	30	Missense	distal	-7	no	140.751	139.315	EPSD	COSMIC	140.458	Loss
CMGC_MAPK_JNK_MAPK9_ST	P04637	TP53	P45984	MAPK9	S37	M44T	44	Missense	distal	7	no	140.751	141.105	EPSD	COSMIC	140.458	Up-regulation
CMGC_MAPK_JNK_MAPK9_ST	P04637	TP53	P45984	MAPK9	S37	A39T	39	Missense	proximal	2	no	140.751	140.917	EPSD	COSMIC	140.458	Up-regulation
CMGC_MAPK_JNK_MAPK9_ST	P04637	TP53	P45984	MAPK9	S37	L43F	43	Missense	distal	6	no	140.751	140.460	EPSD	COSMIC	140.458	Down-regulation
CMGC_MAPK_JNK_MAPK9_ST	P04637	TP53	P45984	MAPK9	S37	D41H	41	Missense	distal	4	no	140.751	140.635	EPSD	COSMIC	140.458	Down-regulation
CMGC_MAPK_JNK_MAPK9_ST	P04637	TP53	P45984	MAPK9	S37	P36R	36	Missense	proximal	-1	no	140.751	140.775	EPSD	COSMIC	140.458	Up-regulation
CMGC_MAPK_JNK_MAPK9_ST	P04637	TP53	P45984	MAPK9	S37	L35R	35	Missense	proximal	-2	no	140.751	140.623	EPSD	COSMIC	140.458	Down-regulation
CMGC_MAPK_JNK_MAPK9_ST	P04637	TP53	P45984	MAPK9	S37	L35H	35	Missense	proximal	-2	no	140.751	137.796	EPSD	COSMIC	140.458	Loss
CMGC_MAPK_JNK_MAPK9_ST	P04637	TP53	P45984	MAPK9	S37	L35P	35	Missense	proximal	-2	no	140.751	141.826	EPSD	COSMIC	140.458	Up-regulation
CMGC_MAPK_JNK_MAPK9_ST	P04637	TP53	P45984	MAPK9	S37	L35I	35	Missense	proximal	-2	no	140.751	138.689	EPSD	COSMIC	140.458	Loss
CMGC_MAPK_JNK_MAPK9_ST	P04637	TP53	P45984	MAPK9	S37	L35V	35	Missense	proximal	-2	no	140.751	137.551	EPSD	COSMIC	140.458	Loss
CMGC_MAPK_JNK_MAPK9_ST	P04637	TP53	P45984	MAPK9	S37	D41E	41	Missense	distal	4	no	140.751	140.385	EPSD	COSMIC	140.458	Loss
CMGC_MAPK_JNK_MAPK9_ST	P04637	TP53	P45984	MAPK9	S46	M40I	40	Missense	distal	-6	no	158.258	157.830	PhosphoSitePlus;EPSD	COSMIC	140.458	Down-regulation
CMGC_MAPK_JNK_MAPK9_ST	P04637	TP53	P45984	MAPK9	S46	W53C	53	Missense	distal	7	no	158.258	157.816	PhosphoSitePlus;EPSD	COSMIC	140.458	Down-regulation
CMGC_MAPK_JNK_MAPK9_ST	P04637	TP53	P45984	MAPK9	S46	W53G	53	Missense	distal	7	no	158.258	157.893	PhosphoSitePlus;EPSD	COSMIC	140.458	Down-regulation
CMGC_MAPK_JNK_MAPK9_ST	P04637	TP53	P45984	MAPK9	S46	S46F	46	Missense	central	0	yes	158.258	0.000	PhosphoSitePlus;EPSD	COSMIC	140.458	Loss
CMGC_MAPK_JNK_MAPK9_ST	P04637	TP53	P45984	MAPK9	S46	D49Y	49	Missense	distal	3	no	158.258	157.970	PhosphoSitePlus;EPSD	COSMIC	140.458	Down-regulation
CMGC_MAPK_JNK_MAPK9_ST	P04637	TP53	P45984	MAPK9	S46	P47L	47	Missense	proximal	1	no	158.258	113.355	PhosphoSitePlus;EPSD	COSMIC	140.458	Loss
CMGC_MAPK_JNK_MAPK9_ST	P04637	TP53	P45984	MAPK9	S46	D49H	49	Missense	distal	3	no	158.258	158.255	PhosphoSitePlus;EPSD	COSMIC;GDSC;CCLE	140.458	Down-regulation
CMGC_MAPK_JNK_MAPK9_ST	P04637	TP53	P45984	MAPK9	S46	P47S	47	Missense	proximal	1	no	158.258	-122.536	PhosphoSitePlus;EPSD	COSMIC	140.458	Loss
CMGC_MAPK_JNK_MAPK9_ST	P04637	TP53	P45984	MAPK9	S46	D41N	41	Missense	distal	-5	no	158.258	158.140	PhosphoSitePlus;EPSD	COSMIC	140.458	Down-regulation
CMGC_MAPK_JNK_MAPK9_ST	P04637	TP53	P45984	MAPK9	S46	D48H	48	Missense	proximal	2	no	158.258	158.271	PhosphoSitePlus;EPSD	COSMIC	140.458	Up-regulation
CMGC_MAPK_JNK_MAPK9_ST	P04637	TP53	P45984	MAPK9	S46	D49N	49	Missense	distal	3	no	158.258	158.497	PhosphoSitePlus;EPSD	COSMIC	140.458	Up-regulation
CMGC_MAPK_JNK_MAPK9_ST	P04637	TP53	P45984	MAPK9	S46	M44I	44	Missense	proximal	-2	no	158.258	156.990	PhosphoSitePlus;EPSD	COSMIC	140.458	Down-regulation
CMGC_MAPK_JNK_MAPK9_ST	P04637	TP53	P45984	MAPK9	S46	Q52H	52	Missense	distal	6	no	158.258	157.799	PhosphoSitePlus;EPSD	COSMIC	140.458	Down-regulation
CMGC_MAPK_JNK_MAPK9_ST	P04637	TP53	P45984	MAPK9	S46	D49V	49	Missense	distal	3	no	158.258	158.293	PhosphoSitePlus;EPSD	COSMIC	140.458	Up-regulation
CMGC_MAPK_JNK_MAPK9_ST	P04637	TP53	P45984	MAPK9	S46	A39V	39	Missense	distal	-7	no	158.258	156.177	PhosphoSitePlus;EPSD	COSMIC	140.458	Down-regulation
CMGC_MAPK_JNK_MAPK9_ST	P04637	TP53	P45984	MAPK9	S46	A39S	39	Missense	distal	-7	no	158.258	157.138	PhosphoSitePlus;EPSD	COSMIC	140.458	Down-regulation
CMGC_MAPK_JNK_MAPK9_ST	P04637	TP53	P45984	MAPK9	S46	D42Y	42	Missense	distal	-4	no	158.258	155.953	PhosphoSitePlus;EPSD	COSMIC	140.458	Down-regulation
CMGC_MAPK_JNK_MAPK9_ST	P04637	TP53	P45984	MAPK9	S46	M44R	44	Missense	proximal	-2	no	158.258	158.923	PhosphoSitePlus;EPSD	COSMIC	140.458	Up-regulation
CMGC_MAPK_JNK_MAPK9_ST	P04637	TP53	P45984	MAPK9	S46	S46P	46	Missense	central	0	yes	158.258	0.000	PhosphoSitePlus;EPSD	COSMIC	140.458	Loss
CMGC_MAPK_JNK_MAPK9_ST	P04637	TP53	P45984	MAPK9	S46	M44V	44	Missense	proximal	-2	no	158.258	155.852	PhosphoSitePlus;EPSD	COSMIC	140.458	Down-regulation
CMGC_MAPK_JNK_MAPK9_ST	P04637	TP53	P45984	MAPK9	S46	L45P	45	Missense	proximal	-1	no	158.258	158.414	PhosphoSitePlus;EPSD	COSMIC	140.458	Up-regulation
CMGC_MAPK_JNK_MAPK9_ST	P04637	TP53	P45984	MAPK9	S46	M44T	44	Missense	proximal	-2	no	158.258	156.490	PhosphoSitePlus;EPSD	COSMIC	140.458	Down-regulation
CMGC_MAPK_JNK_MAPK9_ST	P04637	TP53	P45984	MAPK9	S46	A39T	39	Missense	distal	-7	no	158.258	155.715	PhosphoSitePlus;EPSD	COSMIC	140.458	Down-regulation
CMGC_MAPK_JNK_MAPK9_ST	P04637	TP53	P45984	MAPK9	S46	L43F	43	Missense	distal	-3	no	158.258	155.507	PhosphoSitePlus;EPSD	COSMIC	140.458	Down-regulation
CMGC_MAPK_JNK_MAPK9_ST	P04637	TP53	P45984	MAPK9	S46	D41H	41	Missense	distal	-5	no	158.258	158.233	PhosphoSitePlus;EPSD	COSMIC	140.458	Down-regulation
CMGC_MAPK_JNK_MAPK9_ST	P04637	TP53	P45984	MAPK9	S46	D49E	49	Missense	distal	3	no	158.258	158.406	PhosphoSitePlus;EPSD	COSMIC	140.458	Up-regulation
CMGC_MAPK_JNK_MAPK9_ST	P04637	TP53	P45984	MAPK9	S46	D49G	49	Missense	distal	3	no	158.258	158.209	PhosphoSitePlus;EPSD	COSMIC	140.458	Down-regulation
CMGC_MAPK_JNK_MAPK9_ST	P04637	TP53	P45984	MAPK9	S46	D48A	48	Missense	proximal	2	no	158.258	158.124	PhosphoSitePlus;EPSD	COSMIC	140.458	Down-regulation
CMGC_MAPK_JNK_MAPK9_ST	P04637	TP53	P45984	MAPK9	S46	D48Y	48	Missense	proximal	2	no	158.258	158.440	PhosphoSitePlus;EPSD	COSMIC	140.458	Up-regulation
CMGC_MAPK_JNK_MAPK9_ST	P04637	TP53	P45984	MAPK9	S46	D48E	48	Missense	proximal	2	no	158.258	158.133	PhosphoSitePlus;EPSD	COSMIC	140.458	Down-regulation
CMGC_MAPK_JNK_MAPK9_ST	P04637	TP53	P45984	MAPK9	S46	D49I	49	Missense	distal	3	no	158.258	158.254	PhosphoSitePlus;EPSD	COSMIC	140.458	Down-regulation
CMGC_MAPK_JNK_MAPK9_ST	P04637	TP53	P45984	MAPK9	S46	D41E	41	Missense	distal	-5	no	158.258	158.154	PhosphoSitePlus;EPSD	COSMIC	140.458	Down-regulation
CMGC_MAPK_JNK_MAPK9_ST	P04637	TP53	P45984	MAPK9	T81	P77A	77	Missense	distal	-4	no	166.507	167.241	EPSD	COSMIC	140.458	Up-regulation
CMGC_MAPK_JNK_MAPK9_ST	P04637	TP53	P45984	MAPK9	T81	A76T	76	Missense	distal	-5	no	166.507	166.545	EPSD	COSMIC	140.458	Up-regulation
CMGC_MAPK_JNK_MAPK9_ST	P04637	TP53	P45984	MAPK9	T81	A83T	83	Missense	proximal	2	no	166.507	166.673	EPSD	COSMIC	140.458	Up-regulation
CMGC_MAPK_JNK_MAPK9_ST	P04637	TP53	P45984	MAPK9	T81	T81I	81	Missense	central	0	yes	166.507	0.000	EPSD	COSMIC	140.458	Loss
CMGC_MAPK_JNK_MAPK9_ST	P04637	TP53	P45984	MAPK9	T81	A84V	84	Missense	distal	3	no	166.507	166.334	EPSD	COSMIC	140.458	Down-regulation
CMGC_MAPK_JNK_MAPK9_ST	P04637	TP53	P45984	MAPK9	T81	P80L	80	Missense	proximal	-1	no	166.507	166.351	EPSD	COSMIC	140.458	Down-regulation
CMGC_MAPK_JNK_MAPK9_ST	P04637	TP53	P45984	MAPK9	T81	A86V	86	Missense	distal	5	no	166.507	166.924	EPSD	COSMIC	140.458	Up-regulation
CMGC_MAPK_JNK_MAPK9_ST	P04637	TP53	P45984	MAPK9	T81	P85S	85	Missense	distal	4	no	166.507	166.609	EPSD	COSMIC	140.458	Up-regulation
CMGC_MAPK_JNK_MAPK9_ST	P04637	TP53	P45984	MAPK9	T81	A79T	79	Missense	proximal	-2	no	166.507	164.141	EPSD	COSMIC	140.458	Down-regulation
CMGC_MAPK_JNK_MAPK9_ST	P04637	TP53	P45984	MAPK9	T81	A84G	84	Missense	distal	3	no	166.507	166.251	EPSD	COSMIC	140.458	Down-regulation
CMGC_MAPK_JNK_MAPK9_ST	P04637	TP53	P45984	MAPK9	T81	A78V	78	Missense	distal	-3	no	166.507	165.043	EPSD	COSMIC	140.458	Down-regulation
CMGC_MAPK_JNK_MAPK9_ST	P04637	TP53	P45984	MAPK9	T81	A78S	78	Missense	distal	-3	no	166.507	166.094	EPSD	COSMIC	140.458	Down-regulation
CMGC_MAPK_JNK_MAPK9_ST	P04637	TP53	P45984	MAPK9	T81	P87L	87	Missense	distal	6	no	166.507	166.275	EPSD	COSMIC	140.458	Down-regulation
CMGC_MAPK_JNK_MAPK9_ST	P04637	TP53	P45984	MAPK9	T81	P85L	85	Missense	distal	4	no	166.507	166.883	EPSD	COSMIC	140.458	Up-regulation
CMGC_MAPK_JNK_MAPK9_ST	P04637	TP53	P45984	MAPK9	T81	P82S	82	Missense	proximal	1	no	166.507	-114.287	EPSD	COSMIC	140.458	Loss
CMGC_MAPK_JNK_MAPK9_ST	P04637	TP53	P45984	MAPK9	T81	P77S	77	Missense	distal	-4	no	166.507	166.686	EPSD	COSMIC	140.458	Up-regulation
CMGC_MAPK_JNK_MAPK9_ST	P04637	TP53	P45984	MAPK9	T81	P80S	80	Missense	proximal	-1	no	166.507	166.395	EPSD	COSMIC	140.458	Down-regulation
CMGC_MAPK_JNK_MAPK9_ST	P04637	TP53	P45984	MAPK9	T81	A84T	84	Missense	distal	3	no	166.507	166.296	EPSD	COSMIC	140.458	Down-regulation
CMGC_MAPK_JNK_MAPK9_ST	P04637	TP53	P45984	MAPK9	T81	A83E	83	Missense	proximal	2	no	166.507	166.516	EPSD	COSMIC	140.458	Up-regulation
CMGC_MAPK_JNK_MAPK9_ST	P04637	TP53	P45984	MAPK9	T81	P85T	85	Missense	distal	4	no	166.507	166.707	EPSD	COSMIC	140.458	Up-regulation
CMGC_MAPK_JNK_MAPK9_ST	P04637	TP53	P45984	MAPK9	T81	A74V	74	Missense	distal	-7	no	166.507	164.426	EPSD	COSMIC	140.458	Down-regulation
CMGC_MAPK_JNK_MAPK9_ST	P04637	TP53	P45984	MAPK9	T81	P75S	75	Missense	distal	-6	no	166.507	166.416	EPSD	COSMIC	140.458	Down-regulation
CMGC_MAPK_JNK_MAPK9_ST	P04637	TP53	P45984	MAPK9	T81	A76V	76	Missense	distal	-5	no	166.507	166.571	EPSD	COSMIC	140.458	Up-regulation
CMGC_MAPK_JNK_MAPK9_ST	P04637	TP53	P45984	MAPK9	T81	P75R	75	Missense	distal	-6	no	166.507	166.619	EPSD	COSMIC	140.458	Up-regulation
CMGC_MAPK_JNK_MAPK9_ST	P04637	TP53	P45984	MAPK9	T81	P87H	87	Missense	distal	6	no	166.507	166.280	EPSD	COSMIC	140.458	Down-regulation
CMGC_MAPK_JNK_MAPK9_ST	P04637	TP53	P45984	MAPK9	T81	P87T	87	Missense	distal	6	no	166.507	166.258	EPSD	COSMIC	140.458	Down-regulation
CMGC_MAPK_JNK_MAPK9_ST	P04637	TP53	P45984	MAPK9	T81	P87S	87	Missense	distal	6	no	166.507	166.534	EPSD	COSMIC	140.458	Up-regulation
CMGC_MAPK_JNK_MAPK9_ST	P04637	TP53	P45984	MAPK9	T81	P87R	87	Missense	distal	6	no	166.507	166.571	EPSD	COSMIC	140.458	Up-regulation
CMGC_MAPK_JNK_MAPK9_ST	P04637	TP53	P45984	MAPK9	T81	P87C	87	Missense	distal	6	no	166.507	166.397	EPSD	COSMIC	140.458	Down-regulation
CMGC_MAPK_JNK_MAPK9_ST	P04637	TP53	P45984	MAPK9	T81	A86E	86	Missense	distal	5	no	166.507	166.520	EPSD	COSMIC	140.458	Up-regulation
CMGC_MAPK_JNK_MAPK9_ST	P04637	TP53	P45984	MAPK9	T81	A86S	86	Missense	distal	5	no	166.507	166.496	EPSD	COSMIC	140.458	Down-regulation
CMGC_MAPK_JNK_MAPK9_ST	P04637	TP53	P45984	MAPK9	T81	A83V	83	Missense	proximal	2	no	166.507	166.648	EPSD	COSMIC	140.458	Up-regulation
CMGC_MAPK_JNK_MAPK9_ST	P04637	TP53	P45984	MAPK9	S99	S99F	99	Missense	central	0	yes	140.696	0.000	EPSD	COSMIC	140.458	Loss
CMGC_MAPK_JNK_MAPK9_ST	P04637	TP53	P45984	MAPK9	S99	S96F	96	Missense	distal	-3	no	140.696	137.411	EPSD	COSMIC	140.458	Loss
CMGC_MAPK_JNK_MAPK9_ST	P04637	TP53	P45984	MAPK9	S99	P98S	98	Missense	proximal	-1	no	140.696	140.583	EPSD	COSMIC;CCLE	140.458	Down-regulation
CMGC_MAPK_JNK_MAPK9_ST	P04637	TP53	P45984	MAPK9	S99	T102I	102	Missense	distal	3	no	140.696	140.695	EPSD	COSMIC	140.458	Down-regulation
CMGC_MAPK_JNK_MAPK9_ST	P04637	TP53	P45984	MAPK9	S99	S94P	94	Missense	distal	-5	no	140.696	140.716	EPSD	COSMIC	140.458	Up-regulation
CMGC_MAPK_JNK_MAPK9_ST	P04637	TP53	P45984	MAPK9	S99	K101R	101	Missense	proximal	2	no	140.696	140.619	EPSD	COSMIC	140.458	Down-regulation
CMGC_MAPK_JNK_MAPK9_ST	P04637	TP53	P45984	MAPK9	S99	S94T	94	Missense	distal	-5	no	140.696	140.742	EPSD	COSMIC	140.458	Up-regulation
CMGC_MAPK_JNK_MAPK9_ST	P04637	TP53	P45984	MAPK9	S99	P98L	98	Missense	proximal	-1	no	140.696	140.540	EPSD	COSMIC;GDSC;CCLE	140.458	Down-regulation
CMGC_MAPK_JNK_MAPK9_ST	P04637	TP53	P45984	MAPK9	S99	S95F	95	Missense	distal	-4	no	140.696	137.413	EPSD	COSMIC;CCLE	140.458	Loss
CMGC_MAPK_JNK_MAPK9_ST	P04637	TP53	P45984	MAPK9	S99	S96C	96	Missense	distal	-3	no	140.696	139.856	EPSD	COSMIC	140.458	Loss
CMGC_MAPK_JNK_MAPK9_ST	P04637	TP53	P45984	MAPK9	S99	S106I	106	Missense	distal	7	no	140.696	140.925	EPSD	COSMIC	140.458	Up-regulation
CMGC_MAPK_JNK_MAPK9_ST	P04637	TP53	P45984	MAPK9	S99	P98F	98	Missense	proximal	-1	no	140.696	140.208	EPSD	COSMIC	140.458	Loss
CMGC_MAPK_JNK_MAPK9_ST	P04637	TP53	P45984	MAPK9	S99	T102P	102	Missense	distal	3	no	140.696	140.858	EPSD	COSMIC	140.458	Up-regulation
CMGC_MAPK_JNK_MAPK9_ST	P04637	TP53	P45984	MAPK9	S99	S94L	94	Missense	distal	-5	no	140.696	140.815	EPSD	COSMIC	140.458	Up-regulation
CMGC_MAPK_JNK_MAPK9_ST	P04637	TP53	P45984	MAPK9	S99	S96P	96	Missense	distal	-3	no	140.696	141.735	EPSD	COSMIC	140.458	Up-regulation
CMGC_MAPK_JNK_MAPK9_ST	P04637	TP53	P45984	MAPK9	S99	P98T	98	Missense	proximal	-1	no	140.696	140.406	EPSD	COSMIC	140.458	Loss
CMGC_MAPK_JNK_MAPK9_ST	P04637	TP53	P45984	MAPK9	S99	S96Y	96	Missense	distal	-3	no	140.696	137.390	EPSD	COSMIC	140.458	Loss
CMGC_MAPK_JNK_MAPK9_ST	P04637	TP53	P45984	MAPK9	S99	S99P	99	Missense	central	0	yes	140.696	0.000	EPSD	COSMIC	140.458	Loss
CMGC_MAPK_JNK_MAPK9_ST	P04637	TP53	P45984	MAPK9	S99	V97I	97	Missense	proximal	-2	no	140.696	141.834	EPSD	COSMIC	140.458	Up-regulation
CMGC_MAPK_JNK_MAPK9_ST	P04637	TP53	P45984	MAPK9	S99	Q104H	104	Missense	distal	5	no	140.696	141.237	EPSD	COSMIC	140.458	Up-regulation
CMGC_MAPK_JNK_MAPK9_ST	P04637	TP53	P45984	MAPK9	S99	L93M	93	Missense	distal	-6	no	140.696	141.239	EPSD	COSMIC	140.458	Up-regulation
CMGC_MAPK_JNK_MAPK9_ST	P04637	TP53	P45984	MAPK9	S99	K101N	101	Missense	proximal	2	no	140.696	140.652	EPSD	COSMIC	140.458	Down-regulation
CMGC_MAPK_JNK_MAPK9_ST	P04637	TP53	P45984	MAPK9	S99	V97A	97	Missense	proximal	-2	no	140.696	143.700	EPSD	COSMIC	140.458	Up-regulation
CMGC_MAPK_JNK_MAPK9_ST	P04637	TP53	P45984	MAPK9	S99	P92A	92	Missense	distal	-7	no	140.696	142.847	EPSD	COSMIC	140.458	Up-regulation
CMGC_MAPK_JNK_MAPK9_ST	P04637	TP53	P45984	MAPK9	S99	Q104L	104	Missense	distal	5	no	140.696	141.429	EPSD	COSMIC	140.458	Up-regulation
CMGC_MAPK_JNK_MAPK9_ST	P04637	TP53	P45984	MAPK9	S99	P92L	92	Missense	distal	-7	no	140.696	139.568	EPSD	COSMIC	140.458	Loss
CMGC_MAPK_JNK_MAPK9_ST	P04637	TP53	P45984	MAPK9	S99	L93P	93	Missense	distal	-6	no	140.696	141.138	EPSD	COSMIC	140.458	Up-regulation
CMGC_MAPK_JNK_MAPK9_ST	P04637	TP53	P45984	MAPK9	S99	L93F	93	Missense	distal	-6	no	140.696	140.348	EPSD	COSMIC	140.458	Loss
CMGC_MAPK_JNK_MAPK9_ST	P04637	TP53	P45984	MAPK9	S99	L93H	93	Missense	distal	-6	no	140.696	140.809	EPSD	COSMIC	140.458	Up-regulation
CMGC_MAPK_JNK_MAPK9_ST	P04637	TP53	P45984	MAPK9	S99	S95Y	95	Missense	distal	-4	no	140.696	137.688	EPSD	COSMIC	140.458	Loss
CMGC_MAPK_JNK_MAPK9_ST	P04637	TP53	P45984	MAPK9	S127	C124W	124	Missense	distal	-3	no	145.026	142.716	EPSD	COSMIC	140.458	Down-regulation
CMGC_MAPK_JNK_MAPK9_ST	P04637	TP53	P45984	MAPK9	S127	C124F	124	Missense	distal	-3	no	145.026	142.580	EPSD	COSMIC	140.458	Down-regulation
CMGC_MAPK_JNK_MAPK9_ST	P04637	TP53	P45984	MAPK9	S127	C124S	124	Missense	distal	-3	no	145.026	145.865	EPSD	COSMIC	140.458	Up-regulation
CMGC_MAPK_JNK_MAPK9_ST	P04637	TP53	P45984	MAPK9	S127	S127A	127	Missense	central	0	yes	145.026	0.000	EPSD	COSMIC	140.458	Loss
CMGC_MAPK_JNK_MAPK9_ST	P04637	TP53	P45984	MAPK9	S127	S127L	127	Missense	central	0	yes	145.026	0.000	EPSD	COSMIC	140.458	Loss
CMGC_MAPK_JNK_MAPK9_ST	P04637	TP53	P45984	MAPK9	S127	C124T	124	Missense	distal	-3	no	145.026	145.031	EPSD	COSMIC	140.458	Up-regulation
CMGC_MAPK_JNK_MAPK9_ST	P04637	TP53	P45984	MAPK9	S127	S127I	127	Missense	central	0	yes	145.026	0.000	EPSD	COSMIC	140.458	Loss
CMGC_MAPK_JNK_MAPK9_ST	P04637	TP53	P45984	MAPK9	S127	S127G	127	Missense	central	0	yes	145.026	0.000	EPSD	COSMIC	140.458	Loss
CMGC_MAPK_JNK_MAPK9_ST	P04637	TP53	P45984	MAPK9	S127	N131H	131	Missense	distal	4	no	145.026	145.227	EPSD	COSMIC	140.458	Up-regulation
CMGC_MAPK_JNK_MAPK9_ST	P04637	TP53	P45984	MAPK9	S127	N131D	131	Missense	distal	4	no	145.026	145.344	EPSD	COSMIC	140.458	Up-regulation
CMGC_MAPK_JNK_MAPK9_ST	P04637	TP53	P45984	MAPK9	S127	T125I	125	Missense	proximal	-2	no	145.026	145.525	EPSD	COSMIC	140.458	Up-regulation
CMGC_MAPK_JNK_MAPK9_ST	P04637	TP53	P45984	MAPK9	S127	F134I	134	Missense	distal	7	no	145.026	144.460	EPSD	COSMIC	140.458	Down-regulation
CMGC_MAPK_JNK_MAPK9_ST	P04637	TP53	P45984	MAPK9	S127	K120T	120	Missense	distal	-7	no	145.026	143.153	EPSD	COSMIC	140.458	Down-regulation
CMGC_MAPK_JNK_MAPK9_ST	P04637	TP53	P45984	MAPK9	S127	F134S	134	Missense	distal	7	no	145.026	144.230	EPSD	COSMIC	140.458	Down-regulation
CMGC_MAPK_JNK_MAPK9_ST	P04637	TP53	P45984	MAPK9	S127	T125K	125	Missense	proximal	-2	no	145.026	144.791	EPSD	COSMIC	140.458	Down-regulation
CMGC_MAPK_JNK_MAPK9_ST	P04637	TP53	P45984	MAPK9	S127	M133I	133	Missense	distal	6	no	145.026	144.708	EPSD	COSMIC	140.458	Down-regulation
CMGC_MAPK_JNK_MAPK9_ST	P04637	TP53	P45984	MAPK9	S127	N131K	131	Missense	distal	4	no	145.026	145.074	EPSD	COSMIC;CCLE	140.458	Up-regulation
CMGC_MAPK_JNK_MAPK9_ST	P04637	TP53	P45984	MAPK9	S127	P128S	128	Missense	proximal	1	no	145.026	-135.768	EPSD	COSMIC	140.458	Loss
CMGC_MAPK_JNK_MAPK9_ST	P04637	TP53	P45984	MAPK9	S127	M133L	133	Missense	distal	6	no	145.026	144.707	EPSD	COSMIC	140.458	Down-regulation
CMGC_MAPK_JNK_MAPK9_ST	P04637	TP53	P45984	MAPK9	S127	A129T	129	Missense	proximal	2	no	145.026	145.192	EPSD	COSMIC	140.458	Up-regulation
CMGC_MAPK_JNK_MAPK9_ST	P04637	TP53	P45984	MAPK9	S127	T123I	123	Missense	distal	-4	no	145.026	145.236	EPSD	COSMIC	140.458	Up-regulation
CMGC_MAPK_JNK_MAPK9_ST	P04637	TP53	P45984	MAPK9	S127	A129G	129	Missense	proximal	2	no	145.026	145.167	EPSD	COSMIC	140.458	Up-regulation
CMGC_MAPK_JNK_MAPK9_ST	P04637	TP53	P45984	MAPK9	S127	K132W	132	Missense	distal	5	no	145.026	145.977	EPSD	COSMIC	140.458	Up-regulation
CMGC_MAPK_JNK_MAPK9_ST	P04637	TP53	P45984	MAPK9	S127	A129V	129	Missense	proximal	2	no	145.026	145.166	EPSD	COSMIC	140.458	Up-regulation
CMGC_MAPK_JNK_MAPK9_ST	P04637	TP53	P45984	MAPK9	S127	P128A	128	Missense	proximal	1	no	145.026	126.382	EPSD	COSMIC	140.458	Loss
CMGC_MAPK_JNK_MAPK9_ST	P04637	TP53	P45984	MAPK9	S127	L130I	130	Missense	distal	3	no	145.026	145.171	EPSD	COSMIC	140.458	Up-regulation
CMGC_MAPK_JNK_MAPK9_ST	P04637	TP53	P45984	MAPK9	S127	S121F	121	Missense	distal	-6	no	145.026	144.327	EPSD	COSMIC	140.458	Down-regulation
CMGC_MAPK_JNK_MAPK9_ST	P04637	TP53	P45984	MAPK9	S127	A129D	129	Missense	proximal	2	no	145.026	145.159	EPSD	COSMIC	140.458	Up-regulation
CMGC_MAPK_JNK_MAPK9_ST	P04637	TP53	P45984	MAPK9	S127	K120Q	120	Missense	distal	-7	no	145.026	145.084	EPSD	COSMIC	140.458	Up-regulation
CMGC_MAPK_JNK_MAPK9_ST	P04637	TP53	P45984	MAPK9	S127	T125S	125	Missense	proximal	-2	no	145.026	144.901	EPSD	COSMIC	140.458	Down-regulation
CMGC_MAPK_JNK_MAPK9_ST	P04637	TP53	P45984	MAPK9	S127	P128L	128	Missense	proximal	1	no	145.026	100.123	EPSD	COSMIC	140.458	Loss
CMGC_MAPK_JNK_MAPK9_ST	P04637	TP53	P45984	MAPK9	S127	V122L	122	Missense	distal	-5	no	145.026	145.073	EPSD	COSMIC	140.458	Up-regulation
CMGC_MAPK_JNK_MAPK9_ST	P04637	TP53	P45984	MAPK9	S127	C124L	124	Missense	distal	-3	no	145.026	145.331	EPSD	COSMIC	140.458	Up-regulation
CMGC_MAPK_JNK_MAPK9_ST	P04637	TP53	P45984	MAPK9	S127	N131T	131	Missense	distal	4	no	145.026	145.156	EPSD	COSMIC	140.458	Up-regulation
CMGC_MAPK_JNK_MAPK9_ST	P04637	TP53	P45984	MAPK9	S127	M133V	133	Missense	distal	6	no	145.026	144.820	EPSD	COSMIC	140.458	Down-regulation
CMGC_MAPK_JNK_MAPK9_ST	P04637	TP53	P45984	MAPK9	T150	P151N	151	Missense	proximal	1	no	153.234	-47.135	EPSD	COSMIC	140.458	Loss
CMGC_MAPK_JNK_MAPK9_ST	P04637	TP53	P45984	MAPK9	T150	P152A	152	Missense	proximal	2	no	153.234	153.244	EPSD	COSMIC	140.458	Up-regulation
CMGC_MAPK_JNK_MAPK9_ST	P04637	TP53	P45984	MAPK9	T150	P152T	152	Missense	proximal	2	no	153.234	153.410	EPSD	COSMIC	140.458	Up-regulation
CMGC_MAPK_JNK_MAPK9_ST	P04637	TP53	P45984	MAPK9	T150	P152H	152	Missense	proximal	2	no	153.234	153.391	EPSD	COSMIC	140.458	Up-regulation
CMGC_MAPK_JNK_MAPK9_ST	P04637	TP53	P45984	MAPK9	T150	P153T	153	Missense	distal	3	no	153.234	153.072	EPSD	COSMIC	140.458	Down-regulation
CMGC_MAPK_JNK_MAPK9_ST	P04637	TP53	P45984	MAPK9	T150	V147I	147	Missense	distal	-3	no	153.234	152.896	EPSD	COSMIC	140.458	Down-regulation
CMGC_MAPK_JNK_MAPK9_ST	P04637	TP53	P45984	MAPK9	T150	P153L	153	Missense	distal	3	no	153.234	152.926	EPSD	COSMIC	140.458	Down-regulation
CMGC_MAPK_JNK_MAPK9_ST	P04637	TP53	P45984	MAPK9	T150	V147D	147	Missense	distal	-3	no	153.234	153.688	EPSD	COSMIC;GDSC;CCLE	140.458	Up-regulation
CMGC_MAPK_JNK_MAPK9_ST	P04637	TP53	P45984	MAPK9	T150	S149P	149	Missense	proximal	-1	no	153.234	153.346	EPSD	COSMIC	140.458	Up-regulation
CMGC_MAPK_JNK_MAPK9_ST	P04637	TP53	P45984	MAPK9	T150	P152K	152	Missense	proximal	2	no	153.234	153.284	EPSD	COSMIC	140.458	Up-regulation
CMGC_MAPK_JNK_MAPK9_ST	P04637	TP53	P45984	MAPK9	T150	P153S	153	Missense	distal	3	no	153.234	153.186	EPSD	COSMIC	140.458	Down-regulation
CMGC_MAPK_JNK_MAPK9_ST	P04637	TP53	P45984	MAPK9	T150	G154C	154	Missense	distal	4	no	153.234	153.170	EPSD	COSMIC	140.458	Down-regulation
CMGC_MAPK_JNK_MAPK9_ST	P04637	TP53	P45984	MAPK9	T150	S149F	149	Missense	proximal	-1	no	153.234	152.858	EPSD	COSMIC	140.458	Down-regulation
CMGC_MAPK_JNK_MAPK9_ST	P04637	TP53	P45984	MAPK9	T150	G154D	154	Missense	distal	4	no	153.234	153.311	EPSD	COSMIC	140.458	Up-regulation
CMGC_MAPK_JNK_MAPK9_ST	P04637	TP53	P45984	MAPK9	T150	V157I	157	Missense	distal	7	no	153.234	153.094	EPSD	COSMIC	140.458	Down-regulation
CMGC_MAPK_JNK_MAPK9_ST	P04637	TP53	P45984	MAPK9	T150	W146R	146	Missense	distal	-4	no	153.234	156.564	EPSD	COSMIC	140.458	Up-regulation
CMGC_MAPK_JNK_MAPK9_ST	P04637	TP53	P45984	MAPK9	T150	Q144R	144	Missense	distal	-6	no	153.234	153.306	EPSD	COSMIC	140.458	Up-regulation
CMGC_MAPK_JNK_MAPK9_ST	P04637	TP53	P45984	MAPK9	T150	D148V	148	Missense	proximal	-2	no	153.234	152.751	EPSD	COSMIC	140.458	Down-regulation
CMGC_MAPK_JNK_MAPK9_ST	P04637	TP53	P45984	MAPK9	T150	S149Y	149	Missense	proximal	-1	no	153.234	152.910	EPSD	COSMIC	140.458	Down-regulation
CMGC_MAPK_JNK_MAPK9_ST	P04637	TP53	P45984	MAPK9	T150	T150I	150	Missense	central	0	yes	153.234	0.000	EPSD	COSMIC	140.458	Loss
CMGC_MAPK_JNK_MAPK9_ST	P04637	TP53	P45984	MAPK9	T150	S149T	149	Missense	proximal	-1	no	153.234	153.057	EPSD	COSMIC	140.458	Down-regulation
CMGC_MAPK_JNK_MAPK9_ST	P04637	TP53	P45984	MAPK9	T150	W146G	146	Missense	distal	-4	no	153.234	155.329	EPSD	COSMIC	140.458	Up-regulation
CMGC_MAPK_JNK_MAPK9_ST	P04637	TP53	P45984	MAPK9	T150	L145M	145	Missense	distal	-5	no	153.234	153.100	EPSD	COSMIC	140.458	Down-regulation
CMGC_MAPK_JNK_MAPK9_ST	P04637	TP53	P45984	MAPK9	T150	V143L	143	Missense	distal	-7	no	153.234	152.037	EPSD	COSMIC	140.458	Down-regulation
CMGC_MAPK_JNK_MAPK9_ST	P04637	TP53	P45984	MAPK9	T150	R156S	156	Missense	distal	6	no	153.234	153.197	EPSD	COSMIC	140.458	Down-regulation
CMGC_MAPK_JNK_MAPK9_ST	P04637	TP53	P45984	MAPK9	T150	D148E	148	Missense	proximal	-2	no	153.234	155.223	EPSD	COSMIC	140.458	Up-regulation
CMGC_MAPK_JNK_MAPK9_ST	P04637	TP53	P45984	MAPK9	T150	V147F	147	Missense	distal	-3	no	153.234	151.000	EPSD	COSMIC	140.458	Down-regulation
CMGC_MAPK_JNK_MAPK9_ST	P04637	TP53	P45984	MAPK9	T150	T155A	155	Missense	distal	5	no	153.234	152.855	EPSD	COSMIC	140.458	Down-regulation
CMGC_MAPK_JNK_MAPK9_ST	P04637	TP53	P45984	MAPK9	T150	V147E	147	Missense	distal	-3	no	153.234	154.478	EPSD	COSMIC	140.458	Up-regulation
CMGC_MAPK_JNK_MAPK9_ST	P04637	TP53	P45984	MAPK9	T150	G154I	154	Missense	distal	4	no	153.234	153.218	EPSD	COSMIC	140.458	Down-regulation
CMGC_MAPK_JNK_MAPK9_ST	P04637	TP53	P45984	MAPK9	T150	D148G	148	Missense	proximal	-2	no	153.234	153.158	EPSD	COSMIC	140.458	Down-regulation
CMGC_MAPK_JNK_MAPK9_ST	P04637	TP53	P45984	MAPK9	T150	Q144K	144	Missense	distal	-6	no	153.234	153.118	EPSD	COSMIC	140.458	Down-regulation
CMGC_MAPK_JNK_MAPK9_ST	P04637	TP53	P45984	MAPK9	T150	V147A	147	Missense	distal	-3	no	153.234	154.699	EPSD	COSMIC	140.458	Up-regulation
CMGC_MAPK_JNK_MAPK9_ST	P04637	TP53	P45984	MAPK9	T150	L145V	145	Missense	distal	-5	no	153.234	153.187	EPSD	COSMIC	140.458	Down-regulation
CMGC_MAPK_JNK_MAPK9_ST	P04637	TP53	P45984	MAPK9	T150	T150K	150	Missense	central	0	yes	153.234	0.000	EPSD	COSMIC	140.458	Loss
CMGC_MAPK_JNK_MAPK9_ST	P04637	TP53	P45984	MAPK9	T150	P153H	153	Missense	distal	3	no	153.234	153.072	EPSD	COSMIC	140.458	Down-regulation
CMGC_MAPK_JNK_MAPK9_ST	P04637	TP53	P45984	MAPK9	T150	V157E	157	Missense	distal	7	no	153.234	152.726	EPSD	COSMIC	140.458	Down-regulation
CMGC_MAPK_JNK_MAPK9_ST	P04637	TP53	P45984	MAPK9	T150	T155S	155	Missense	distal	5	no	153.234	152.844	EPSD	COSMIC;CCLE	140.458	Down-regulation
CMGC_MAPK_JNK_MAPK9_ST	P04637	TP53	P45984	MAPK9	T150	D148H	148	Missense	proximal	-2	no	153.234	152.996	EPSD	COSMIC	140.458	Down-regulation
CMGC_MAPK_JNK_MAPK9_ST	P04637	TP53	P45984	MAPK9	T150	P153A	153	Missense	distal	3	no	153.234	153.283	EPSD	COSMIC	140.458	Up-regulation
CMGC_MAPK_JNK_MAPK9_ST	P04637	TP53	P45984	MAPK9	T150	T150R	150	Missense	central	0	yes	153.234	0.000	EPSD	COSMIC	140.458	Loss
CMGC_MAPK_JNK_MAPK9_ST	P04637	TP53	P45984	MAPK9	T150	T155L	155	Missense	distal	5	no	153.234	153.554	EPSD	COSMIC	140.458	Up-regulation
CMGC_MAPK_JNK_MAPK9_ST	P04637	TP53	P45984	MAPK9	T150	G154A	154	Missense	distal	4	no	153.234	152.953	EPSD	COSMIC	140.458	Down-regulation
CMGC_MAPK_JNK_MAPK9_ST	P04637	TP53	P45984	MAPK9	T150	T150A	150	Missense	central	0	yes	153.234	0.000	EPSD	COSMIC	140.458	Loss
CMGC_MAPK_JNK_MAPK9_ST	P04637	TP53	P45984	MAPK9	T150	W146C	146	Missense	distal	-4	no	153.234	155.592	EPSD	COSMIC	140.458	Up-regulation
CMGC_MAPK_JNK_MAPK9_ST	P04637	TP53	P45984	MAPK9	T150	P153F	153	Missense	distal	3	no	153.234	152.834	EPSD	COSMIC	140.458	Down-regulation
CMGC_MAPK_JNK_MAPK9_ST	P04637	TP53	P45984	MAPK9	T150	D148Y	148	Missense	proximal	-2	no	153.234	151.504	EPSD	COSMIC	140.458	Down-regulation
CMGC_MAPK_JNK_MAPK9_ST	P04637	TP53	P45984	MAPK9	T150	G154R	154	Missense	distal	4	no	153.234	152.914	EPSD	COSMIC	140.458	Down-regulation
CMGC_MAPK_JNK_MAPK9_ST	P04637	TP53	P45984	MAPK9	S183	G187V	187	Missense	distal	4	no	144.606	144.550	EPSD	COSMIC	140.458	Down-regulation
CMGC_MAPK_JNK_MAPK9_ST	P04637	TP53	P45984	MAPK9	S183	G187D	187	Missense	distal	4	no	144.606	144.684	EPSD	COSMIC	140.458	Up-regulation
CMGC_MAPK_JNK_MAPK9_ST	P04637	TP53	P45984	MAPK9	S183	G187A	187	Missense	distal	4	no	144.606	144.325	EPSD	COSMIC	140.458	Down-regulation
CMGC_MAPK_JNK_MAPK9_ST	P04637	TP53	P45984	MAPK9	S183	S183C	183	Missense	central	0	yes	144.606	0.000	EPSD	COSMIC	140.458	Loss
CMGC_MAPK_JNK_MAPK9_ST	P04637	TP53	P45984	MAPK9	S183	S183P	183	Missense	central	0	yes	144.606	0.000	EPSD	COSMIC	140.458	Loss
CMGC_MAPK_JNK_MAPK9_ST	P04637	TP53	P45984	MAPK9	S183	S185G	185	Missense	proximal	2	no	144.606	144.662	EPSD	COSMIC	140.458	Up-regulation
CMGC_MAPK_JNK_MAPK9_ST	P04637	TP53	P45984	MAPK9	S183	P190N	190	Missense	distal	7	no	144.606	144.659	EPSD	COSMIC	140.458	Up-regulation
CMGC_MAPK_JNK_MAPK9_ST	P04637	TP53	P45984	MAPK9	S183	D184N	184	Missense	proximal	1	no	144.606	-40.357	EPSD	COSMIC	140.458	Loss
CMGC_MAPK_JNK_MAPK9_ST	P04637	TP53	P45984	MAPK9	S183	S185R	185	Missense	proximal	2	no	144.606	144.485	EPSD	COSMIC	140.458	Down-regulation
CMGC_MAPK_JNK_MAPK9_ST	P04637	TP53	P45984	MAPK9	S183	S183L	183	Missense	central	0	yes	144.606	0.000	EPSD	COSMIC	140.458	Loss
CMGC_MAPK_JNK_MAPK9_ST	P04637	TP53	P45984	MAPK9	S183	R181L	181	Missense	proximal	-2	no	144.606	144.735	EPSD	COSMIC	140.458	Up-regulation
CMGC_MAPK_JNK_MAPK9_ST	P04637	TP53	P45984	MAPK9	S183	H178P	178	Missense	distal	-5	no	144.606	144.558	EPSD	COSMIC	140.458	Down-regulation
CMGC_MAPK_JNK_MAPK9_ST	P04637	TP53	P45984	MAPK9	S183	D186N	186	Missense	distal	3	no	144.606	144.846	EPSD	COSMIC	140.458	Up-regulation
CMGC_MAPK_JNK_MAPK9_ST	P04637	TP53	P45984	MAPK9	S183	A189S	189	Missense	distal	6	no	144.606	144.470	EPSD	COSMIC	140.458	Down-regulation
CMGC_MAPK_JNK_MAPK9_ST	P04637	TP53	P45984	MAPK9	S183	H178L	178	Missense	distal	-5	no	144.606	144.658	EPSD	COSMIC	140.458	Up-regulation
CMGC_MAPK_JNK_MAPK9_ST	P04637	TP53	P45984	MAPK9	S183	D184Y	184	Missense	proximal	1	no	144.606	-158.569	EPSD	COSMIC	140.458	Loss
CMGC_MAPK_JNK_MAPK9_ST	P04637	TP53	P45984	MAPK9	S183	L188V	188	Missense	distal	5	no	144.606	144.324	EPSD	COSMIC	140.458	Down-regulation
CMGC_MAPK_JNK_MAPK9_ST	P04637	TP53	P45984	MAPK9	S183	A189V	189	Missense	distal	6	no	144.606	144.324	EPSD	COSMIC	140.458	Down-regulation
CMGC_MAPK_JNK_MAPK9_ST	P04637	TP53	P45984	MAPK9	S183	H178Y	178	Missense	distal	-5	no	144.606	144.687	EPSD	COSMIC	140.458	Up-regulation
CMGC_MAPK_JNK_MAPK9_ST	P04637	TP53	P45984	MAPK9	S183	D186E	186	Missense	distal	3	no	144.606	144.755	EPSD	COSMIC	140.458	Up-regulation
CMGC_MAPK_JNK_MAPK9_ST	P04637	TP53	P45984	MAPK9	S183	C182Y	182	Missense	proximal	-1	no	144.606	144.328	EPSD	COSMIC	140.458	Down-regulation
CMGC_MAPK_JNK_MAPK9_ST	P04637	TP53	P45984	MAPK9	S183	D186H	186	Missense	distal	3	no	144.606	144.603	EPSD	COSMIC	140.458	Down-regulation
CMGC_MAPK_JNK_MAPK9_ST	P04637	TP53	P45984	MAPK9	S183	L188Q	188	Missense	distal	5	no	144.606	143.873	EPSD	COSMIC	140.458	Down-regulation
CMGC_MAPK_JNK_MAPK9_ST	P04637	TP53	P45984	MAPK9	S183	H178N	178	Missense	distal	-5	no	144.606	144.514	EPSD	COSMIC	140.458	Down-regulation
CMGC_MAPK_JNK_MAPK9_ST	P04637	TP53	P45984	MAPK9	S183	G187R	187	Missense	distal	4	no	144.606	144.286	EPSD	COSMIC;GDSC	140.458	Down-regulation
CMGC_MAPK_JNK_MAPK9_ST	P04637	TP53	P45984	MAPK9	S183	C182S	182	Missense	proximal	-1	no	144.606	144.652	EPSD	COSMIC	140.458	Up-regulation
CMGC_MAPK_JNK_MAPK9_ST	P04637	TP53	P45984	MAPK9	S183	P190F	190	Missense	distal	7	no	144.606	145.631	EPSD	COSMIC	140.458	Up-regulation
CMGC_MAPK_JNK_MAPK9_ST	P04637	TP53	P45984	MAPK9	S183	G187C	187	Missense	distal	4	no	144.606	144.543	EPSD	COSMIC	140.458	Down-regulation
CMGC_MAPK_JNK_MAPK9_ST	P04637	TP53	P45984	MAPK9	S183	S185T	185	Missense	proximal	2	no	144.606	144.687	EPSD	COSMIC	140.458	Up-regulation
CMGC_MAPK_JNK_MAPK9_ST	P04637	TP53	P45984	MAPK9	S183	P190H	190	Missense	distal	7	no	144.606	145.010	EPSD	COSMIC	140.458	Up-regulation
CMGC_MAPK_JNK_MAPK9_ST	P04637	TP53	P45984	MAPK9	S183	S185N	185	Missense	proximal	2	no	144.606	144.517	EPSD	COSMIC	140.458	Down-regulation
CMGC_MAPK_JNK_MAPK9_ST	P04637	TP53	P45984	MAPK9	S183	D186G	186	Missense	distal	3	no	144.606	144.558	EPSD	COSMIC	140.458	Down-regulation
CMGC_MAPK_JNK_MAPK9_ST	P04637	TP53	P45984	MAPK9	S183	D186V	186	Missense	distal	3	no	144.606	144.641	EPSD	COSMIC	140.458	Up-regulation
CMGC_MAPK_JNK_MAPK9_ST	P04637	TP53	P45984	MAPK9	S183	P177I	177	Missense	distal	-6	no	144.606	144.279	EPSD	COSMIC	140.458	Down-regulation
CMGC_MAPK_JNK_MAPK9_ST	P04637	TP53	P45984	MAPK9	S183	P190A	190	Missense	distal	7	no	144.606	144.530	EPSD	COSMIC	140.458	Down-regulation
CMGC_MAPK_JNK_MAPK9_ST	P04637	TP53	P45984	MAPK9	S183	S185C	185	Missense	proximal	2	no	144.606	144.638	EPSD	COSMIC	140.458	Up-regulation
CMGC_MAPK_JNK_MAPK9_ST	P04637	TP53	P45984	MAPK9	S183	S185I	185	Missense	proximal	2	no	144.606	144.659	EPSD	COSMIC	140.458	Up-regulation
CMGC_MAPK_JNK_MAPK9_ST	P04637	TP53	P45984	MAPK9	S183	A189P	189	Missense	distal	6	no	144.606	144.444	EPSD	COSMIC	140.458	Down-regulation
CMGC_MAPK_JNK_MAPK9_ST	P04637	TP53	P45984	MAPK9	S183	E180Q	180	Missense	distal	-3	no	144.606	144.910	EPSD	COSMIC	140.458	Up-regulation
CMGC_MAPK_JNK_MAPK9_ST	P04637	TP53	P45984	MAPK9	S183	R181S	181	Missense	proximal	-2	no	144.606	142.048	EPSD	COSMIC	140.458	Down-regulation
CMGC_MAPK_JNK_MAPK9_ST	P04637	TP53	P45984	MAPK9	S183	C182R	182	Missense	proximal	-1	no	144.606	144.788	EPSD	COSMIC	140.458	Up-regulation
CMGC_MAPK_JNK_MAPK9_ST	P04637	TP53	P45984	MAPK9	S183	E180G	180	Missense	distal	-3	no	144.606	143.148	EPSD	COSMIC	140.458	Down-regulation
CMGC_MAPK_JNK_MAPK9_ST	P04637	TP53	P45984	MAPK9	S183	L188M	188	Missense	distal	5	no	144.606	143.814	EPSD	COSMIC	140.458	Down-regulation
CMGC_MAPK_JNK_MAPK9_ST	P04637	TP53	P45984	MAPK9	S183	P177F	177	Missense	distal	-6	no	144.606	143.816	EPSD	COSMIC	140.458	Down-regulation
CMGC_MAPK_JNK_MAPK9_ST	P04637	TP53	P45984	MAPK9	S183	D184E	184	Missense	proximal	1	no	144.606	139.120	EPSD	COSMIC	140.458	Loss
CMGC_MAPK_JNK_MAPK9_ST	P04637	TP53	P45984	MAPK9	S183	A189G	189	Missense	distal	6	no	144.606	144.294	EPSD	COSMIC	140.458	Down-regulation
CMGC_MAPK_JNK_MAPK9_ST	P04637	TP53	P45984	MAPK9	S183	R181G	181	Missense	proximal	-2	no	144.606	141.942	EPSD	COSMIC	140.458	Down-regulation
CMGC_MAPK_JNK_MAPK9_ST	P04637	TP53	P45984	MAPK9	S183	D186X	186	Missense	distal	3	no	144.606	144.585	EPSD	COSMIC	140.458	Down-regulation
CMGC_MAPK_JNK_MAPK9_ST	P04637	TP53	P45984	MAPK9	S183	R181Y	181	Missense	proximal	-2	no	144.606	140.287	EPSD	COSMIC	140.458	Loss
CMGC_MAPK_JNK_MAPK9_ST	P04637	TP53	P45984	MAPK9	S183	D184G	184	Missense	proximal	1	no	144.606	-15.878	EPSD	COSMIC	140.458	Loss
CMGC_MAPK_JNK_MAPK9_ST	P04637	TP53	P45984	MAPK9	T304	K305T	305	Missense	proximal	1	no	-7.079	142.641	EPSD	COSMIC	140.458	Gain
CMGC_MAPK_JNK_MAPK9_ST	P04637	TP53	P45984	MAPK9	T304	K305E	305	Missense	proximal	1	no	-7.079	140.945	EPSD	COSMIC	140.458	Gain
CMGC_MAPK_JNK_MAPK9_ST	P04637	TP53	P45984	MAPK9	S314	S315P	315	Missense	proximal	1	no	-118.510	162.284	EPSD	COSMIC	140.458	Gain
CMGC_MAPK_JNK_MAPK9_ST	P04637	TP53	P45984	MAPK9	S315	N310T	310	Missense	distal	-5	no	155.450	155.520	EPSD	COSMIC	140.458	Up-regulation
CMGC_MAPK_JNK_MAPK9_ST	P04637	TP53	P45984	MAPK9	S315	Q317R	317	Missense	proximal	2	no	155.450	155.405	EPSD	COSMIC	140.458	Down-regulation
CMGC_MAPK_JNK_MAPK9_ST	P04637	TP53	P45984	MAPK9	S315	P309S	309	Missense	distal	-6	no	155.450	155.358	EPSD	COSMIC;GDSC;CCLE	140.458	Down-regulation
CMGC_MAPK_JNK_MAPK9_ST	P04637	TP53	P45984	MAPK9	S315	K319E	319	Missense	distal	4	no	155.450	155.353	EPSD	COSMIC	140.458	Down-regulation
CMGC_MAPK_JNK_MAPK9_ST	P04637	TP53	P45984	MAPK9	S315	P322L	322	Missense	distal	7	no	155.450	156.089	EPSD	COSMIC	140.458	Up-regulation
CMGC_MAPK_JNK_MAPK9_ST	P04637	TP53	P45984	MAPK9	S315	K320N	320	Missense	distal	5	no	155.450	155.053	EPSD	COSMIC;GDSC;CCLE	140.458	Down-regulation
CMGC_MAPK_JNK_MAPK9_ST	P04637	TP53	P45984	MAPK9	S315	N310L	310	Missense	distal	-5	no	155.450	155.594	EPSD	COSMIC	140.458	Up-regulation
CMGC_MAPK_JNK_MAPK9_ST	P04637	TP53	P45984	MAPK9	S315	T312S	312	Missense	distal	-3	no	155.450	156.284	EPSD	COSMIC	140.458	Up-regulation
CMGC_MAPK_JNK_MAPK9_ST	P04637	TP53	P45984	MAPK9	S315	N311Y	311	Missense	distal	-4	no	155.450	151.124	EPSD	COSMIC	140.458	Down-regulation
CMGC_MAPK_JNK_MAPK9_ST	P04637	TP53	P45984	MAPK9	S315	P322R	322	Missense	distal	7	no	155.450	155.256	EPSD	COSMIC	140.458	Down-regulation
CMGC_MAPK_JNK_MAPK9_ST	P04637	TP53	P45984	MAPK9	S315	N311K	311	Missense	distal	-4	no	155.450	153.230	EPSD	COSMIC	140.458	Down-regulation
CMGC_MAPK_JNK_MAPK9_ST	P04637	TP53	P45984	MAPK9	S315	Q317K	317	Missense	proximal	2	no	155.450	155.481	EPSD	COSMIC	140.458	Up-regulation
CMGC_MAPK_JNK_MAPK9_ST	P04637	TP53	P45984	MAPK9	S315	S315P	315	Missense	central	0	yes	155.450	0.000	EPSD	COSMIC	140.458	Loss
CMGC_MAPK_JNK_MAPK9_ST	P04637	TP53	P45984	MAPK9	S315	N310H	310	Missense	distal	-5	no	155.450	155.542	EPSD	COSMIC	140.458	Up-regulation
CMGC_MAPK_JNK_MAPK9_ST	P04637	TP53	P45984	MAPK9	S315	S314C	314	Missense	proximal	-1	no	155.450	155.404	EPSD	COSMIC	140.458	Down-regulation
CMGC_MAPK_JNK_MAPK9_ST	P04637	TP53	P45984	MAPK9	S315	P318A	318	Missense	distal	3	no	155.450	155.499	EPSD	COSMIC	140.458	Up-regulation
CMGC_MAPK_JNK_MAPK9_ST	P04637	TP53	P45984	MAPK9	S315	P316L	316	Missense	proximal	1	no	155.450	110.547	EPSD	COSMIC	140.458	Loss
CMGC_MAPK_JNK_MAPK9_ST	P04637	TP53	P45984	MAPK9	S315	L308M	308	Missense	distal	-7	no	155.450	157.964	EPSD	COSMIC	140.458	Up-regulation
CMGC_MAPK_JNK_MAPK9_ST	P04637	TP53	P45984	MAPK9	S315	S313C	313	Missense	proximal	-2	no	155.450	156.240	EPSD	COSMIC	140.458	Up-regulation
CMGC_MAPK_JNK_MAPK9_ST	P04637	TP53	P45984	MAPK9	S315	N311H	311	Missense	distal	-4	no	155.450	152.193	EPSD	COSMIC	140.458	Down-regulation
CMGC_MAPK_JNK_MAPK9_ST	P04637	TP53	P45984	MAPK9	S315	L308V	308	Missense	distal	-7	no	155.450	156.647	EPSD	COSMIC	140.458	Up-regulation
CMGC_MAPK_JNK_MAPK9_ST	P04637	TP53	P45984	MAPK9	S315	S314F	314	Missense	proximal	-1	no	155.450	155.074	EPSD	COSMIC	140.458	Down-regulation
CMGC_MAPK_JNK_MAPK9_ST	P04637	TP53	P45984	MAPK9	S315	K319R	319	Missense	distal	4	no	155.450	155.322	EPSD	COSMIC	140.458	Down-regulation
CMGC_MAPK_JNK_MAPK9_ST	P04637	TP53	P45984	MAPK9	S315	T312A	312	Missense	distal	-3	no	155.450	156.698	EPSD	COSMIC	140.458	Up-regulation
CMGC_MAPK_JNK_MAPK9_ST	P04637	TP53	P45984	MAPK9	S315	N310D	310	Missense	distal	-5	no	155.450	155.568	EPSD	COSMIC	140.458	Up-regulation
CMGC_MAPK_JNK_MAPK9_ST	P04637	TP53	P45984	MAPK9	S315	N311D	311	Missense	distal	-4	no	155.450	153.428	EPSD	COSMIC	140.458	Down-regulation
CMGC_MAPK_JNK_MAPK9_ST	P04637	TP53	P45984	MAPK9	S315	P309R	309	Missense	distal	-6	no	155.450	155.561	EPSD	COSMIC	140.458	Up-regulation
CMGC_MAPK_JNK_MAPK9_ST	P04637	TP53	P45984	MAPK9	S315	S313N	313	Missense	proximal	-2	no	155.450	156.563	EPSD	COSMIC	140.458	Up-regulation
CMGC_MAPK_JNK_MAPK9_ST	P04637	TP53	P45984	MAPK9	S315	Q317P	317	Missense	proximal	2	no	155.450	155.431	EPSD	COSMIC	140.458	Down-regulation
CMGC_MAPK_JNK_MAPK9_ST	P04637	TP53	P45984	MAPK9	S315	P316S	316	Missense	proximal	1	no	155.450	-125.344	EPSD	COSMIC	140.458	Loss
CMGC_MAPK_JNK_MAPK9_ST	P04637	TP53	P45984	MAPK9	S378	R379P	379	Missense	proximal	1	no	118.653	156.241	EPSD	COSMIC	140.458	Gain
CMGC_MAPK_JNK_MAPK9_ST	Q9UIG0	BAZ1B	P45984	MAPK9	S46	S46R	46	Missense	central	0	yes	142.052	0.000	EPSD	COSMIC	140.458	Loss
CMGC_MAPK_JNK_MAPK9_ST	Q9UIG0	BAZ1B	P45984	MAPK9	S46	T51M	51	Missense	distal	5	no	142.052	141.580	EPSD	COSMIC	140.458	Down-regulation
CMGC_MAPK_JNK_MAPK9_ST	Q9UIG0	BAZ1B	P45984	MAPK9	S197	T203S	203	Missense	distal	6	no	161.590	161.866	EPSD	COSMIC	140.458	Up-regulation
CMGC_MAPK_JNK_MAPK9_ST	Q9UIG0	BAZ1B	P45984	MAPK9	S349	S347G	347	Missense	proximal	-2	no	148.899	148.793	EPSD	COSMIC	140.458	Down-regulation
CMGC_MAPK_JNK_MAPK9_ST	Q9UIG0	BAZ1B	P45984	MAPK9	S361	P362L	362	Missense	proximal	1	no	152.171	107.268	EPSD	COSMIC	140.458	Loss
CMGC_MAPK_JNK_MAPK9_ST	Q9UIG0	BAZ1B	P45984	MAPK9	S423	L428M	428	Missense	distal	5	no	150.878	150.086	EPSD	COSMIC	140.458	Down-regulation
CMGC_MAPK_JNK_MAPK9_ST	Q9UIG0	BAZ1B	P45984	MAPK9	T430	K432Q	432	Missense	proximal	2	no	156.033	156.002	EPSD	COSMIC	140.458	Down-regulation
CMGC_MAPK_JNK_MAPK9_ST	Q9UIG0	BAZ1B	P45984	MAPK9	T430	L428M	428	Missense	proximal	-2	no	156.033	155.239	EPSD	COSMIC	140.458	Down-regulation
CMGC_MAPK_JNK_MAPK9_ST	Q9UIG0	BAZ1B	P45984	MAPK9	T430	K432I	432	Missense	proximal	2	no	156.033	156.130	EPSD	COSMIC;GDSC;CCLE	140.458	Up-regulation
CMGC_MAPK_JNK_MAPK9_ST	Q9UIG0	BAZ1B	P45984	MAPK9	T460	P461S	461	Missense	proximal	1	no	154.003	-126.791	EPSD	COSMIC	140.458	Loss
CMGC_MAPK_JNK_MAPK9_ST	Q9UIG0	BAZ1B	P45984	MAPK9	T460	R455W	455	Missense	distal	-5	no	154.003	154.136	EPSD	COSMIC	140.458	Up-regulation
CMGC_MAPK_JNK_MAPK9_ST	Q9UIG0	BAZ1B	P45984	MAPK9	S699	E706K	706	Missense	distal	7	no	146.550	146.801	EPSD	COSMIC	140.458	Up-regulation
CMGC_MAPK_JNK_MAPK9_ST	Q9UIG0	BAZ1B	P45984	MAPK9	S699	D700E	700	Missense	proximal	1	no	146.550	141.064	EPSD	COSMIC	140.458	Down-regulation
CMGC_MAPK_JNK_MAPK9_ST	Q9UIG0	BAZ1B	P45984	MAPK9	S699	R698S	698	Missense	proximal	-1	no	146.550	146.414	EPSD	COSMIC	140.458	Down-regulation
CMGC_MAPK_JNK_MAPK9_ST	Q9UIG0	BAZ1B	P45984	MAPK9	S708	E706K	706	Missense	proximal	-2	no	145.957	143.888	EPSD	COSMIC	140.458	Down-regulation
CMGC_MAPK_JNK_MAPK9_ST	Q9UIG0	BAZ1B	P45984	MAPK9	S708	D712H	712	Missense	distal	4	no	145.957	145.840	EPSD	COSMIC	140.458	Down-regulation
CMGC_MAPK_JNK_MAPK9_ST	Q9UIG0	BAZ1B	P45984	MAPK9	S708	D712Y	712	Missense	distal	4	no	145.957	146.178	EPSD	COSMIC	140.458	Up-regulation
CMGC_MAPK_JNK_MAPK9_ST	Q9UIG0	BAZ1B	P45984	MAPK9	S716	D712H	712	Missense	distal	-4	no	141.426	140.190	EPSD	COSMIC	140.458	Loss
CMGC_MAPK_JNK_MAPK9_ST	Q9UIG0	BAZ1B	P45984	MAPK9	S716	A717T	717	Missense	proximal	1	no	141.426	140.874	EPSD	COSMIC;GDSC;CCLE	140.458	Down-regulation
CMGC_MAPK_JNK_MAPK9_ST	Q9UIG0	BAZ1B	P45984	MAPK9	S716	D712Y	712	Missense	distal	-4	no	141.426	139.121	EPSD	COSMIC	140.458	Loss
CMGC_MAPK_JNK_MAPK9_ST	Q9UIG0	BAZ1B	P45984	MAPK9	S1249	E1255D	1255	Missense	distal	6	no	141.448	141.173	EPSD	COSMIC	140.458	Down-regulation
CMGC_MAPK_JNK_MAPK9_ST	Q9UIG0	BAZ1B	P45984	MAPK9	S1251	E1255D	1255	Missense	distal	4	no	140.733	141.100	EPSD	COSMIC	140.458	Up-regulation
CMGC_MAPK_JNK_MAPK9_ST	Q9UIG0	BAZ1B	P45984	MAPK9	S1254	E1255D	1255	Missense	proximal	1	no	139.596	145.082	EPSD	COSMIC	140.458	Gain
CMGC_MAPK_JNK_MAPK9_ST	Q9UIG0	BAZ1B	P45984	MAPK9	S1259	E1255D	1255	Missense	distal	-4	no	141.753	140.834	EPSD	COSMIC	140.458	Down-regulation
CMGC_MAPK_JNK_MAPK9_ST	Q9UIG0	BAZ1B	P45984	MAPK9	S1315	A1319V	1319	Missense	distal	4	no	143.880	144.105	EPSD	COSMIC	140.458	Up-regulation
CMGC_MAPK_JNK_MAPK9_ST	P30307	CDC25C	P45984	MAPK9	T48	L54V	54	Missense	distal	6	no	149.860	149.973	EPSD	COSMIC	140.458	Up-regulation
CMGC_MAPK_JNK_MAPK9_ST	P30307	CDC25C	P45984	MAPK9	T48	V50A	50	Missense	proximal	2	no	149.860	149.720	EPSD	COSMIC	140.458	Down-regulation
CMGC_MAPK_JNK_MAPK9_ST	P30307	CDC25C	P45984	MAPK9	T48	P49Q	49	Missense	proximal	1	no	149.860	129.748	EPSD	COSMIC	140.458	Loss
CMGC_MAPK_JNK_MAPK9_ST	P30307	CDC25C	P45984	MAPK9	T48	F53L	53	Missense	distal	5	no	149.860	149.382	EPSD	COSMIC	140.458	Down-regulation
CMGC_MAPK_JNK_MAPK9_ST	P30307	CDC25C	P45984	MAPK9	T67	R70L	70	Missense	distal	3	no	149.859	149.442	EPSD	COSMIC	140.458	Down-regulation
CMGC_MAPK_JNK_MAPK9_ST	P30307	CDC25C	P45984	MAPK9	S122	S122N	122	Missense	central	0	yes	153.441	0.000	EPSD	COSMIC	140.458	Loss
CMGC_MAPK_JNK_MAPK9_ST	P30307	CDC25C	P45984	MAPK9	S129	P131S	131	Missense	proximal	2	no	142.814	142.909	EPSD	COSMIC	140.458	Up-regulation
CMGC_MAPK_JNK_MAPK9_ST	P30307	CDC25C	P45984	MAPK9	S129	S122N	122	Missense	distal	-7	no	142.814	144.700	EPSD	COSMIC	140.458	Up-regulation
CMGC_MAPK_JNK_MAPK9_ST	P30307	CDC25C	P45984	MAPK9	S129	P131L	131	Missense	proximal	2	no	142.814	142.969	EPSD	COSMIC;GDSC;CCLE	140.458	Up-regulation
CMGC_MAPK_JNK_MAPK9_ST	P30307	CDC25C	P45984	MAPK9	T130	P131S	131	Missense	proximal	1	no	150.521	-130.273	EPSD	COSMIC	140.458	Loss
CMGC_MAPK_JNK_MAPK9_ST	P30307	CDC25C	P45984	MAPK9	T130	P131L	131	Missense	proximal	1	no	150.521	105.619	EPSD	COSMIC;GDSC;CCLE	140.458	Loss
CMGC_MAPK_JNK_MAPK9_ST	P30307	CDC25C	P45984	MAPK9	T130	G137R	137	Missense	distal	7	no	150.521	149.773	EPSD	COSMIC	140.458	Down-regulation
CMGC_MAPK_JNK_MAPK9_ST	P30307	CDC25C	P45984	MAPK9	S168	S168F	168	Missense	central	0	yes	156.872	0.000	PhosphoSitePlus	COSMIC	140.458	Loss
CMGC_MAPK_JNK_MAPK9_ST	P30307	CDC25C	P45984	MAPK9	S168	S161L	161	Missense	distal	-7	no	156.872	154.713	PhosphoSitePlus	COSMIC	140.458	Down-regulation
CMGC_MAPK_JNK_MAPK9_ST	P30307	CDC25C	P45984	MAPK9	T171	S168F	168	Missense	distal	-3	no	143.899	140.614	EPSD	COSMIC	140.458	Down-regulation
CMGC_MAPK_JNK_MAPK9_ST	P30307	CDC25C	P45984	MAPK9	S191	A187E	187	Missense	distal	-4	no	140.501	140.162	EPSD	COSMIC	140.458	Loss
CMGC_MAPK_JNK_MAPK9_ST	P30307	CDC25C	P45984	MAPK9	S191	S198F	198	Missense	distal	7	no	140.501	141.296	EPSD	COSMIC	140.458	Up-regulation
CMGC_MAPK_JNK_MAPK9_ST	P30307	CDC25C	P45984	MAPK9	S191	E189K	189	Missense	proximal	-2	no	140.501	138.432	EPSD	COSMIC	140.458	Loss
CMGC_MAPK_JNK_MAPK9_ST	P30307	CDC25C	P45984	MAPK9	S191	S191L	191	Missense	central	0	yes	140.501	0.000	EPSD	COSMIC	140.458	Loss
CMGC_MAPK_JNK_MAPK9_ST	P30307	CDC25C	P45984	MAPK9	S191	E189D	189	Missense	proximal	-2	no	140.501	138.512	EPSD	COSMIC	140.458	Loss
CMGC_MAPK_JNK_MAPK9_ST	P30307	CDC25C	P45984	MAPK9	S214	S216L	216	Missense	proximal	2	no	155.121	155.181	EPSD	COSMIC	140.458	Up-regulation
CMGC_MAPK_JNK_MAPK9_ST	P30307	CDC25C	P45984	MAPK9	S214	G210R	210	Missense	distal	-4	no	155.121	156.357	EPSD	COSMIC	140.458	Up-regulation
CMGC_MAPK_JNK_MAPK9_ST	P31645	SLC6A4	P45984	MAPK9	S52	Y47C	47	Missense	distal	-5	no	155.179	155.085	EPSD	COSMIC	140.458	Down-regulation
CMGC_MAPK_JNK_MAPK9_ST	P31645	SLC6A4	P45984	MAPK9	S52	G56E	56	Missense	distal	4	no	155.179	154.890	EPSD	COSMIC	140.458	Down-regulation
CMGC_MAPK_JNK_MAPK9_ST	P31645	SLC6A4	P45984	MAPK9	T616	G623R	623	Missense	distal	7	no	150.792	150.043	PhosphoSitePlus	COSMIC	140.458	Down-regulation
CMGC_MAPK_JNK_MAPK9_ST	P55957	BID	P45984	MAPK9	T59	S64T	64	Missense	distal	5	no	149.467	149.857	PhosphoSitePlus	COSMIC	140.458	Up-regulation
CMGC_MAPK_JNK_MAPK9_ST	P55957	BID	P45984	MAPK9	T59	H66L	66	Missense	distal	7	no	149.467	149.703	PhosphoSitePlus	COSMIC	140.458	Up-regulation
CMGC_MAPK_JNK_MAPK9_ST	Q8IW41	MAPKAPK5	P45984	MAPK9	T182	Q184E	184	Missense	proximal	2	no	153.789	153.790	PhosphoSitePlus	COSMIC	140.458	Up-regulation
CMGC_MAPK_JNK_MAPK9_ST	Q8IW41	MAPKAPK5	P45984	MAPK9	T182	T186I	186	Missense	distal	4	no	153.789	153.883	PhosphoSitePlus	COSMIC	140.458	Up-regulation
CMGC_MAPK_JNK_MAPK9_ST	Q8IW41	MAPKAPK5	P45984	MAPK9	T186	Q184E	184	Missense	proximal	-2	no	151.094	150.493	EPSD	COSMIC	140.458	Down-regulation
CMGC_MAPK_JNK_MAPK9_ST	Q8IW41	MAPKAPK5	P45984	MAPK9	T186	T186I	186	Missense	central	0	yes	151.094	0.000	EPSD	COSMIC	140.458	Loss
CMGC_MAPK_JNK_MAPK9_ST	P29966	MARCKS	P45984	MAPK9	S118	A122T	122	Missense	distal	4	no	162.494	162.665	EPSD	COSMIC	140.458	Up-regulation
CMGC_MAPK_JNK_MAPK9_ST	P29966	MARCKS	P45984	MAPK9	S118	T120M	120	Missense	proximal	2	no	162.494	162.306	EPSD	COSMIC	140.458	Down-regulation
CMGC_MAPK_JNK_MAPK9_ST	P29966	MARCKS	P45984	MAPK9	T120	A122T	122	Missense	proximal	2	no	140.766	140.932	EPSD	COSMIC	140.458	Up-regulation
CMGC_MAPK_JNK_MAPK9_ST	P29966	MARCKS	P45984	MAPK9	T120	T120M	120	Missense	central	0	yes	140.766	0.000	EPSD	COSMIC	140.458	Loss
CMGC_MAPK_JNK_MAPK9_ST	P29966	MARCKS	P45984	MAPK9	S128	A122T	122	Missense	distal	-6	no	145.975	145.621	EPSD	COSMIC	140.458	Down-regulation
CMGC_MAPK_JNK_MAPK9_ST	P29966	MARCKS	P45984	MAPK9	S128	S131A	131	Missense	distal	3	no	145.975	146.072	EPSD	COSMIC	140.458	Up-regulation
CMGC_MAPK_JNK_MAPK9_ST	P29966	MARCKS	P45984	MAPK9	S132	S131A	131	Missense	proximal	-1	no	145.868	145.950	EPSD	COSMIC	140.458	Up-regulation
CMGC_MAPK_JNK_MAPK9_ST	P29966	MARCKS	P45984	MAPK9	S135	S131A	131	Missense	distal	-4	no	160.014	160.569	EPSD	COSMIC	140.458	Up-regulation
CMGC_MAPK_JNK_MAPK9_ST	P29966	MARCKS	P45984	MAPK9	S135	A142P	142	Missense	distal	7	no	160.014	160.090	EPSD	COSMIC	140.458	Up-regulation
CMGC_MAPK_JNK_MAPK9_ST	P29966	MARCKS	P45984	MAPK9	T143	A142P	142	Missense	proximal	-1	no	160.528	160.557	EPSD	COSMIC	140.458	Up-regulation
CMGC_MAPK_JNK_MAPK9_ST	P29966	MARCKS	P45984	MAPK9	S145	A142P	142	Missense	distal	-3	no	164.178	164.803	EPSD	COSMIC	140.458	Up-regulation
CMGC_MAPK_JNK_MAPK9_ST	P29966	MARCKS	P45984	MAPK9	S252	A251D	251	Missense	proximal	-1	no	148.517	148.293	EPSD	COSMIC	140.458	Down-regulation
CMGC_MAPK_JNK_MAPK9_ST	P29966	MARCKS	P45984	MAPK9	S308	A302V	302	Missense	distal	-6	no	145.391	145.071	EPSD	COSMIC;GDSC;CCLE	140.458	Down-regulation
CMGC_MAPK_JNK_MAPK9_ST	P11802	CDK4	P45984	MAPK9	T172	V174M	174	Missense	proximal	2	no	155.631	155.468	PhosphoSitePlus	COSMIC	140.458	Down-regulation
CMGC_MAPK_JNK_MAPK9_ST	P11802	CDK4	P45984	MAPK9	T172	Q168E	168	Missense	distal	-4	no	155.631	154.715	PhosphoSitePlus	COSMIC	140.458	Down-regulation
CMGC_MAPK_JNK_MAPK9_ST	P11802	CDK4	P45984	MAPK9	T172	T172R	172	Missense	central	0	yes	155.631	0.000	PhosphoSitePlus	COSMIC	140.458	Loss
CMGC_MAPK_JNK_MAPK9_ST	P11802	CDK4	P45984	MAPK9	T172	V175F	175	Missense	distal	3	no	155.631	155.355	PhosphoSitePlus	COSMIC	140.458	Down-regulation
CMGC_MAPK_JNK_MAPK9_ST	Q15750	TAB1	P45984	MAPK9	S339	A343T	343	Missense	distal	4	no	144.136	144.307	EPSD	COSMIC	140.458	Up-regulation
CMGC_MAPK_JNK_MAPK9_ST	Q15750	TAB1	P45984	MAPK9	T376	M372I	372	Missense	distal	-4	no	144.197	142.461	EPSD	COSMIC	140.458	Down-regulation
CMGC_MAPK_JNK_MAPK9_ST	Q15750	TAB1	P45984	MAPK9	T376	S373G	373	Missense	distal	-3	no	144.197	142.931	EPSD	COSMIC	140.458	Down-regulation
CMGC_MAPK_JNK_MAPK9_ST	Q15750	TAB1	P45984	MAPK9	T376	E371K	371	Missense	distal	-5	no	144.197	144.229	EPSD	COSMIC	140.458	Up-regulation
CMGC_MAPK_JNK_MAPK9_ST	Q15750	TAB1	P45984	MAPK9	S378	M372I	372	Missense	distal	-6	no	146.804	146.376	EPSD	COSMIC	140.458	Down-regulation
CMGC_MAPK_JNK_MAPK9_ST	Q15750	TAB1	P45984	MAPK9	S378	S373G	373	Missense	distal	-5	no	146.804	146.871	EPSD	COSMIC	140.458	Up-regulation
CMGC_MAPK_JNK_MAPK9_ST	Q15750	TAB1	P45984	MAPK9	S378	E371K	371	Missense	distal	-7	no	146.804	146.352	EPSD	COSMIC	140.458	Down-regulation
CMGC_MAPK_JNK_MAPK9_ST	Q15750	TAB1	P45984	MAPK9	T431	T435I	435	Missense	distal	4	no	154.477	154.571	EPSD	COSMIC	140.458	Up-regulation
CMGC_MAPK_JNK_MAPK9_ST	Q15750	TAB1	P45984	MAPK9	T431	Q437K	437	Missense	distal	6	no	154.477	154.231	EPSD	COSMIC	140.458	Down-regulation
CMGC_MAPK_JNK_MAPK9_ST	Q15750	TAB1	P45984	MAPK9	S438	P439L	439	Missense	proximal	1	no	155.886	110.983	PhosphoSitePlus	COSMIC	140.458	Loss
CMGC_MAPK_JNK_MAPK9_ST	Q15750	TAB1	P45984	MAPK9	S438	T435I	435	Missense	distal	-3	no	155.886	155.331	PhosphoSitePlus	COSMIC	140.458	Down-regulation
CMGC_MAPK_JNK_MAPK9_ST	Q15750	TAB1	P45984	MAPK9	S438	Q437K	437	Missense	proximal	-1	no	155.886	155.791	PhosphoSitePlus	COSMIC	140.458	Down-regulation
CMGC_MAPK_JNK_MAPK9_ST	Q9UQF2	MAPK8IP1	P45984	MAPK9	S15	F22L	22	Missense	distal	7	no	155.179	154.794	EPSD	COSMIC	140.458	Down-regulation
CMGC_MAPK_JNK_MAPK9_ST	Q9UQF2	MAPK8IP1	P45984	MAPK9	S15	G10A	10	Missense	distal	-5	no	155.179	155.119	EPSD	COSMIC	140.458	Down-regulation
CMGC_MAPK_JNK_MAPK9_ST	Q9UQF2	MAPK8IP1	P45984	MAPK9	S20	F22L	22	Missense	proximal	2	no	161.699	161.522	EPSD	COSMIC	140.458	Down-regulation
CMGC_MAPK_JNK_MAPK9_ST	Q9UQF2	MAPK8IP1	P45984	MAPK9	S29	F22L	22	Missense	distal	-7	no	152.576	153.356	EPSD	COSMIC	140.458	Up-regulation
CMGC_MAPK_JNK_MAPK9_ST	Q9UQF2	MAPK8IP1	P45984	MAPK9	S29	S29L	29	Missense	central	0	yes	152.576	0.000	EPSD	COSMIC;CCLE	140.458	Loss
CMGC_MAPK_JNK_MAPK9_ST	Q9UQF2	MAPK8IP1	P45984	MAPK9	T103	D102Y	102	Missense	proximal	-1	no	156.598	156.415	PhosphoSitePlus	COSMIC	140.458	Down-regulation
CMGC_MAPK_JNK_MAPK9_ST	Q9UQF2	MAPK8IP1	P45984	MAPK9	T103	A99V	99	Missense	distal	-4	no	156.598	154.941	PhosphoSitePlus	COSMIC	140.458	Down-regulation
CMGC_MAPK_JNK_MAPK9_ST	Q9UQF2	MAPK8IP1	P45984	MAPK9	S197	K200Q	200	Missense	distal	3	no	155.359	155.501	EPSD	COSMIC	140.458	Up-regulation
CMGC_MAPK_JNK_MAPK9_ST	Q9UQF2	MAPK8IP1	P45984	MAPK9	S197	R194G	194	Missense	distal	-3	no	155.359	153.375	EPSD	COSMIC	140.458	Down-regulation
CMGC_MAPK_JNK_MAPK9_ST	Q9UQF2	MAPK8IP1	P45984	MAPK9	S197	R191Q	191	Missense	distal	-6	no	155.359	155.287	EPSD	COSMIC	140.458	Down-regulation
CMGC_MAPK_JNK_MAPK9_ST	Q9UQF2	MAPK8IP1	P45984	MAPK9	T205	K200Q	200	Missense	distal	-5	no	153.729	153.703	EPSD	COSMIC	140.458	Down-regulation
CMGC_MAPK_JNK_MAPK9_ST	Q9UQF2	MAPK8IP1	P45984	MAPK9	S235	R239H	239	Missense	distal	4	no	153.307	153.588	EPSD	COSMIC	140.458	Up-regulation
CMGC_MAPK_JNK_MAPK9_ST	Q9UQF2	MAPK8IP1	P45984	MAPK9	S235	S232Y	232	Missense	distal	-3	no	153.307	150.001	EPSD	COSMIC	140.458	Down-regulation
CMGC_MAPK_JNK_MAPK9_ST	Q9UQF2	MAPK8IP1	P45984	MAPK9	S235	R238C	238	Missense	distal	3	no	153.307	153.014	EPSD	COSMIC	140.458	Down-regulation
CMGC_MAPK_JNK_MAPK9_ST	Q9UQF2	MAPK8IP1	P45984	MAPK9	S235	D234H	234	Missense	proximal	-1	no	153.307	153.316	EPSD	COSMIC	140.458	Up-regulation
CMGC_MAPK_JNK_MAPK9_ST	Q9UQF2	MAPK8IP1	P45984	MAPK9	S235	D228Y	228	Missense	distal	-7	no	153.307	150.627	EPSD	COSMIC	140.458	Down-regulation
CMGC_MAPK_JNK_MAPK9_ST	Q9UQF2	MAPK8IP1	P45984	MAPK9	S235	D228H	228	Missense	distal	-7	no	153.307	152.674	EPSD	COSMIC	140.458	Down-regulation
CMGC_MAPK_JNK_MAPK9_ST	Q9UQF2	MAPK8IP1	P45984	MAPK9	S235	R229H	229	Missense	distal	-6	no	153.307	152.866	EPSD	COSMIC	140.458	Down-regulation
CMGC_MAPK_JNK_MAPK9_ST	Q9UQF2	MAPK8IP1	P45984	MAPK9	T284	P285T	285	Missense	proximal	1	no	151.662	132.467	EPSD	COSMIC	140.458	Loss
CMGC_MAPK_JNK_MAPK9_ST	Q9UQF2	MAPK8IP1	P45984	MAPK9	T284	E280D	280	Missense	distal	-4	no	151.662	150.742	EPSD	COSMIC	140.458	Down-regulation
CMGC_MAPK_JNK_MAPK9_ST	Q9UQF2	MAPK8IP1	P45984	MAPK9	T284	Q287H	287	Missense	distal	3	no	151.662	151.415	EPSD	COSMIC	140.458	Down-regulation
CMGC_MAPK_JNK_MAPK9_ST	Q9UQF2	MAPK8IP1	P45984	MAPK9	S311	A317T	317	Missense	distal	6	no	141.853	141.441	EPSD	COSMIC	140.458	Down-regulation
CMGC_MAPK_JNK_MAPK9_ST	Q9UQF2	MAPK8IP1	P45984	MAPK9	S311	M307I	307	Missense	distal	-4	no	141.853	140.116	EPSD	COSMIC	140.458	Loss
CMGC_MAPK_JNK_MAPK9_ST	Q9UQF2	MAPK8IP1	P45984	MAPK9	S311	E304K	304	Missense	distal	-7	no	141.853	141.401	EPSD	COSMIC;GDSC;CCLE	140.458	Down-regulation
CMGC_MAPK_JNK_MAPK9_ST	Q9UQF2	MAPK8IP1	P45984	MAPK9	S311	A316V	316	Missense	distal	5	no	141.853	142.270	EPSD	COSMIC	140.458	Up-regulation
CMGC_MAPK_JNK_MAPK9_ST	Q9UQF2	MAPK8IP1	P45984	MAPK9	S369	Y376C	376	Missense	distal	7	no	143.394	142.884	EPSD	COSMIC	140.458	Down-regulation
CMGC_MAPK_JNK_MAPK9_ST	Q9UQF2	MAPK8IP1	P45984	MAPK9	S421	G428R	428	Missense	distal	7	no	145.512	144.763	EPSD	COSMIC;GDSC;CCLE	140.458	Down-regulation
CMGC_MAPK_JNK_MAPK9_ST	Q9UQF2	MAPK8IP1	P45984	MAPK9	S421	P422T	422	Missense	proximal	1	no	145.512	126.316	EPSD	COSMIC	140.458	Loss
CMGC_MAPK_JNK_MAPK9_ST	Q9UQF2	MAPK8IP1	P45984	MAPK9	S421	S420F	420	Missense	proximal	-1	no	145.512	145.136	EPSD	COSMIC	140.458	Down-regulation
CMGC_MAPK_JNK_MAPK9_ST	Q9UQF2	MAPK8IP1	P45984	MAPK9	S421	S421L	421	Missense	central	0	yes	145.512	0.000	EPSD	COSMIC;GDSC	140.458	Loss
CMGC_MAPK_JNK_MAPK9_ST	Q9UQF2	MAPK8IP1	P45984	MAPK9	S447	E445K	445	Missense	proximal	-2	no	143.353	141.285	EPSD	COSMIC	140.458	Down-regulation
CMGC_MAPK_JNK_MAPK9_ST	Q9UQF2	MAPK8IP1	P45984	MAPK9	S447	V454D	454	Missense	distal	7	no	143.353	143.526	EPSD	COSMIC	140.458	Up-regulation
CMGC_MAPK_JNK_MAPK9_ST	Q9UQF2	MAPK8IP1	P45984	MAPK9	S447	P440H	440	Missense	distal	-7	no	143.353	143.219	EPSD	COSMIC	140.458	Down-regulation
CMGC_MAPK_JNK_MAPK9_ST	Q9UQF2	MAPK8IP1	P45984	MAPK9	S447	P449H	449	Missense	proximal	2	no	143.353	143.510	EPSD	COSMIC	140.458	Up-regulation
CMGC_MAPK_JNK_MAPK9_ST	Q9UQF2	MAPK8IP1	P45984	MAPK9	S447	V454I	454	Missense	distal	7	no	143.353	143.213	EPSD	COSMIC;GDSC	140.458	Down-regulation
CMGC_MAPK_JNK_MAPK9_ST	Q9UQF2	MAPK8IP1	P45984	MAPK9	S447	T448M	448	Missense	proximal	1	no	143.353	98.330	EPSD	COSMIC	140.458	Loss
CMGC_MAPK_JNK_MAPK9_ST	Q9UQF2	MAPK8IP1	P45984	MAPK9	S447	D446Y	446	Missense	proximal	-1	no	143.353	143.170	EPSD	COSMIC;GDSC;CCLE	140.458	Down-regulation
CMGC_MAPK_JNK_MAPK9_ST	Q9UQF2	MAPK8IP1	P45984	MAPK9	S447	D450G	450	Missense	distal	3	no	143.353	143.305	EPSD	COSMIC	140.458	Down-regulation
CMGC_MAPK_JNK_MAPK9_ST	Q9UQF2	MAPK8IP1	P45984	MAPK9	T448	E445K	445	Missense	distal	-3	no	164.131	162.857	EPSD	COSMIC	140.458	Down-regulation
CMGC_MAPK_JNK_MAPK9_ST	Q9UQF2	MAPK8IP1	P45984	MAPK9	T448	V454D	454	Missense	distal	6	no	164.131	164.116	EPSD	COSMIC	140.458	Down-regulation
CMGC_MAPK_JNK_MAPK9_ST	Q9UQF2	MAPK8IP1	P45984	MAPK9	T448	P449H	449	Missense	proximal	1	no	164.131	4.026	EPSD	COSMIC	140.458	Loss
CMGC_MAPK_JNK_MAPK9_ST	Q9UQF2	MAPK8IP1	P45984	MAPK9	T448	V454I	454	Missense	distal	6	no	164.131	164.019	EPSD	COSMIC;GDSC	140.458	Down-regulation
CMGC_MAPK_JNK_MAPK9_ST	Q9UQF2	MAPK8IP1	P45984	MAPK9	T448	T448M	448	Missense	central	0	yes	164.131	0.000	EPSD	COSMIC	140.458	Loss
CMGC_MAPK_JNK_MAPK9_ST	Q9UQF2	MAPK8IP1	P45984	MAPK9	T448	D446Y	446	Missense	proximal	-2	no	164.131	162.401	EPSD	COSMIC;GDSC;CCLE	140.458	Down-regulation
CMGC_MAPK_JNK_MAPK9_ST	Q9UQF2	MAPK8IP1	P45984	MAPK9	T448	D450G	450	Missense	proximal	2	no	164.131	164.139	EPSD	COSMIC	140.458	Up-regulation
CMGC_MAPK_JNK_MAPK9_ST	P98177	FOXO4	P45984	MAPK9	S111	I110V	110	Missense	proximal	-1	no	141.839	141.818	EPSD	COSMIC	140.458	Down-regulation
CMGC_MAPK_JNK_MAPK9_ST	P98177	FOXO4	P45984	MAPK9	S111	S116N	116	Missense	distal	5	no	141.839	141.610	EPSD	COSMIC	140.458	Down-regulation
CMGC_MAPK_JNK_MAPK9_ST	P98177	FOXO4	P45984	MAPK9	S111	P118L	118	Missense	distal	7	no	141.839	142.479	EPSD	COSMIC	140.458	Up-regulation
CMGC_MAPK_JNK_MAPK9_ST	P98177	FOXO4	P45984	MAPK9	T227	P222Q	222	Missense	distal	-5	no	158.510	158.486	EPSD	COSMIC	140.458	Down-regulation
CMGC_MAPK_JNK_MAPK9_ST	P98177	FOXO4	P45984	MAPK9	T227	G225D	225	Missense	proximal	-2	no	158.510	158.585	EPSD	COSMIC	140.458	Up-regulation
CMGC_MAPK_JNK_MAPK9_ST	P98177	FOXO4	P45984	MAPK9	T227	A226S	226	Missense	proximal	-1	no	158.510	158.427	EPSD	COSMIC	140.458	Down-regulation
CMGC_MAPK_JNK_MAPK9_ST	P98177	FOXO4	P45984	MAPK9	T227	G225S	225	Missense	proximal	-2	no	158.510	158.616	EPSD	COSMIC	140.458	Up-regulation
CMGC_MAPK_JNK_MAPK9_ST	P98177	FOXO4	P45984	MAPK9	T227	P228T	228	Missense	proximal	1	no	158.510	139.314	EPSD	COSMIC	140.458	Loss
CMGC_MAPK_JNK_MAPK9_ST	P98177	FOXO4	P45984	MAPK9	T227	P231H	231	Missense	distal	4	no	158.510	158.780	EPSD	COSMIC	140.458	Up-regulation
CMGC_MAPK_JNK_MAPK9_ST	P98177	FOXO4	P45984	MAPK9	S230	G225D	225	Missense	distal	-5	no	161.553	161.579	EPSD	COSMIC	140.458	Up-regulation
CMGC_MAPK_JNK_MAPK9_ST	P98177	FOXO4	P45984	MAPK9	S230	A226S	226	Missense	distal	-4	no	161.553	160.998	EPSD	COSMIC	140.458	Down-regulation
CMGC_MAPK_JNK_MAPK9_ST	P98177	FOXO4	P45984	MAPK9	S230	G225S	225	Missense	distal	-5	no	161.553	161.485	EPSD	COSMIC	140.458	Down-regulation
CMGC_MAPK_JNK_MAPK9_ST	P98177	FOXO4	P45984	MAPK9	S230	P228T	228	Missense	proximal	-2	no	161.553	157.917	EPSD	COSMIC	140.458	Down-regulation
CMGC_MAPK_JNK_MAPK9_ST	P98177	FOXO4	P45984	MAPK9	S230	P231H	231	Missense	proximal	1	no	161.553	1.447	EPSD	COSMIC	140.458	Loss
CMGC_MAPK_JNK_MAPK9_ST	P98177	FOXO4	P45984	MAPK9	S272	T269N	269	Missense	distal	-3	no	158.925	160.414	EPSD	COSMIC	140.458	Up-regulation
CMGC_MAPK_JNK_MAPK9_ST	P98177	FOXO4	P45984	MAPK9	T455	A460S	460	Missense	distal	5	no	161.686	161.674	PhosphoSitePlus;EPSD	COSMIC	140.458	Down-regulation
CMGC_MAPK_JNK_MAPK9_ST	Q9NYV6	RRN3	P45984	MAPK9	S170	D171E	171	Missense	proximal	1	no	144.726	139.240	EPSD	COSMIC	140.458	Loss
CMGC_MAPK_JNK_MAPK9_ST	Q9NYV6	RRN3	P45984	MAPK9	T623	P624L	624	Missense	proximal	1	no	155.505	110.603	EPSD	COSMIC	140.458	Loss
CMGC_MAPK_JNK_MAPK9_ST	Q9NYV6	RRN3	P45984	MAPK9	T623	N616S	616	Missense	distal	-7	no	155.505	153.619	EPSD	COSMIC	140.458	Down-regulation
CMGC_MAPK_JNK_MAPK9_ST	Q9NYV6	RRN3	P45984	MAPK9	T623	T629M	629	Missense	distal	6	no	155.505	155.841	EPSD	COSMIC	140.458	Up-regulation
CMGC_MAPK_JNK_MAPK9_ST	Q9NYV6	RRN3	P45984	MAPK9	T623	T618I	618	Missense	distal	-5	no	155.505	155.554	EPSD	COSMIC;CCLE	140.458	Up-regulation
CMGC_MAPK_JNK_MAPK9_ST	Q9NYV6	RRN3	P45984	MAPK9	S633	T629M	629	Missense	distal	-4	no	147.592	149.539	EPSD	COSMIC	140.458	Up-regulation
CMGC_MAPK_JNK_MAPK9_ST	Q9NYV6	RRN3	P45984	MAPK9	S649	P650S	650	Missense	proximal	1	no	149.789	-131.005	EPSD	COSMIC	140.458	Loss
CMGC_MAPK_JNK_MAPK9_ST	Q9NYV6	RRN3	P45984	MAPK9	S649	P650L	650	Missense	proximal	1	no	149.789	104.887	EPSD	COSMIC	140.458	Loss
CMGC_MAPK_JNK_MAPK9_ST	Q9NYV6	RRN3	P45984	MAPK9	S649	P648H	648	Missense	proximal	-1	no	149.789	149.545	EPSD	COSMIC	140.458	Down-regulation
CMGC_MAPK_JNK_MAPK9_ST	Q9BQQ3	GORASP1	P45984	MAPK9	T216	P214L	214	Missense	proximal	-2	no	149.327	148.253	EPSD	COSMIC	140.458	Down-regulation
CMGC_MAPK_JNK_MAPK9_ST	Q9BQQ3	GORASP1	P45984	MAPK9	T216	P217T	217	Missense	proximal	1	no	149.327	130.132	EPSD	COSMIC	140.458	Loss
CMGC_MAPK_JNK_MAPK9_ST	Q9BQQ3	GORASP1	P45984	MAPK9	T216	K211N	211	Missense	distal	-5	no	149.327	149.281	EPSD	COSMIC;GDSC;CCLE	140.458	Down-regulation
CMGC_MAPK_JNK_MAPK9_ST	Q9BQQ3	GORASP1	P45984	MAPK9	S241	S248P	248	Missense	distal	7	no	153.698	153.469	EPSD	COSMIC	140.458	Down-regulation
CMGC_MAPK_JNK_MAPK9_ST	Q9BQQ3	GORASP1	P45984	MAPK9	S274	P275L	275	Missense	proximal	1	no	160.623	115.720	PhosphoSitePlus	COSMIC	140.458	Loss
CMGC_MAPK_JNK_MAPK9_ST	Q9BQQ3	GORASP1	P45984	MAPK9	S274	P280A	280	Missense	distal	6	no	160.623	160.786	PhosphoSitePlus	COSMIC	140.458	Up-regulation
CMGC_MAPK_JNK_MAPK9_ST	Q06481	APLP2	P45984	MAPK9	T736	E739D	739	Missense	distal	3	no	161.299	161.151	PhosphoSitePlus	COSMIC	140.458	Down-regulation
CMGC_MAPK_JNK_MAPK9_ST	Q06481	APLP2	P45984	MAPK9	T736	R740C	740	Missense	distal	4	no	161.299	161.556	PhosphoSitePlus	COSMIC	140.458	Up-regulation
CMGC_MAPK_JNK_MAPK9_ST	Q06481	APLP2	P45984	MAPK9	T736	P733S	733	Missense	distal	-3	no	161.299	160.260	PhosphoSitePlus	COSMIC	140.458	Down-regulation
AGC_NDR_LATS_LATS2_ST	Q9NQS7	INCENP	Q9NRM7	LATS2	S50	S50N	50	Missense	central	0	yes	0.053	0.000	EPSD	COSMIC	0.004	Loss
AGC_NDR_LATS_LATS2_ST	Q9NQS7	INCENP	Q9NRM7	LATS2	S300	R297H	297	Missense	distal	-3	no	0.049	0.000	EPSD	COSMIC	0.004	Loss
AGC_NDR_LATS_LATS2_ST	Q9NQS7	INCENP	Q9NRM7	LATS2	S302	R297H	297	Missense	distal	-5	no	-0.004	0.008	EPSD	COSMIC	0.004	Gain
AGC_NDR_LATS_LATS2_ST	Q9NQS7	INCENP	Q9NRM7	LATS2	S314	S311F	311	Missense	distal	-3	no	0.001	0.005	EPSD	COSMIC	0.004	Gain
AGC_NDR_LATS_LATS2_ST	Q9NQS7	INCENP	Q9NRM7	LATS2	S336	R333C	333	Missense	distal	-3	no	0.047	-0.001	EPSD	COSMIC	0.004	Loss
AGC_NDR_LATS_LATS2_ST	Q9NQS7	INCENP	Q9NRM7	LATS2	S373	E366V	366	Missense	distal	-7	no	0.003	0.004	EPSD	COSMIC	0.004	Gain
AGC_NDR_LATS_LATS2_ST	Q9NQS7	INCENP	Q9NRM7	LATS2	S452	S458R	458	Missense	distal	6	no	0.048	0.047	EPSD	COSMIC;CCLE	0.004	Down-regulation
AGC_NDR_LATS_LATS2_ST	Q9NQS7	INCENP	Q9NRM7	LATS2	S909	S910R	910	Missense	proximal	1	no	0.046	0.047	EPSD	COSMIC	0.004	Up-regulation
AGC_NDR_LATS_LATS2_ST	Q9NQS7	INCENP	Q9NRM7	LATS2	S909	S910I	910	Missense	proximal	1	no	0.046	0.047	EPSD	COSMIC	0.004	Up-regulation
AGC_NDR_LATS_LATS2_ST	P38936	CDKN1A	Q9NRM7	LATS2	T97	G90R	90	Missense	distal	-7	no	0.047	0.046	EPSD	COSMIC	0.004	Down-regulation
AGC_NDR_LATS_LATS2_ST	P38936	CDKN1A	Q9NRM7	LATS2	T97	T97I	97	Missense	central	0	yes	0.047	0.000	EPSD	COSMIC	0.004	Loss
AGC_NDR_LATS_LATS2_ST	P38936	CDKN1A	Q9NRM7	LATS2	S114	S114L	114	Missense	central	0	yes	0.006	0.000	EPSD	COSMIC	0.004	Loss
AGC_NDR_LATS_LATS2_ST	P38936	CDKN1A	Q9NRM7	LATS2	S114	D109H	109	Missense	distal	-5	no	0.006	0.016	EPSD	COSMIC	0.004	Up-regulation
AGC_NDR_LATS_LATS2_ST	P38936	CDKN1A	Q9NRM7	LATS2	T145	D149N	149	Missense	distal	4	no	0.041	0.040	EPSD	COSMIC	0.004	Down-regulation
AGC_NDR_LATS_LATS2_ST	P38936	CDKN1A	Q9NRM7	LATS2	S146	R143W	143	Missense	distal	-3	no	0.054	0.007	PhosphoSitePlus	COSMIC;GDSC;CCLE	0.004	Down-regulation
AGC_NDR_LATS_LATS2_ST	P38936	CDKN1A	Q9NRM7	LATS2	S146	G139C	139	Missense	distal	-7	no	0.054	0.053	PhosphoSitePlus	COSMIC	0.004	Down-regulation
AGC_NDR_LATS_LATS2_ST	P00519	ABL1	Q9NRM7	LATS2	S50	R47G	47	Missense	distal	-3	no	0.050	-0.001	EPSD	COSMIC	0.004	Loss
AGC_NDR_LATS_LATS2_ST	P00519	ABL1	Q9NRM7	LATS2	S81	G76E	76	Missense	distal	-5	no	0.004	0.003	EPSD	COSMIC	0.004	Loss
AGC_NDR_LATS_LATS2_ST	P00519	ABL1	Q9NRM7	LATS2	S162	R166K	166	Missense	distal	4	no	0.004	0.003	EPSD	COSMIC;CCLE	0.004	Loss
AGC_NDR_LATS_LATS2_ST	P00519	ABL1	Q9NRM7	LATS2	S162	S162F	162	Missense	central	0	yes	0.004	0.000	EPSD	COSMIC	0.004	Loss
AGC_NDR_LATS_LATS2_ST	P00519	ABL1	Q9NRM7	LATS2	S164	R166K	166	Missense	proximal	2	no	0.042	0.043	EPSD	COSMIC;CCLE	0.004	Up-regulation
AGC_NDR_LATS_LATS2_ST	P00519	ABL1	Q9NRM7	LATS2	T178	L184R	184	Missense	distal	6	no	0.067	0.066	EPSD	COSMIC	0.004	Down-regulation
AGC_NDR_LATS_LATS2_ST	P00519	ABL1	Q9NRM7	LATS2	S187	L184R	184	Missense	distal	-3	no	0.003	0.053	EPSD	COSMIC	0.004	Gain
AGC_NDR_LATS_LATS2_ST	P00519	ABL1	Q9NRM7	LATS2	T224	R220H	220	Missense	distal	-4	no	0.004	0.003	EPSD	COSMIC	0.004	Loss
AGC_NDR_LATS_LATS2_ST	P00519	ABL1	Q9NRM7	LATS2	T389	R386Q	386	Missense	distal	-3	no	0.047	-0.002	EPSD	COSMIC	0.004	Loss
AGC_NDR_LATS_LATS2_ST	P00519	ABL1	Q9NRM7	LATS2	T389	L384M	384	Missense	distal	-5	no	0.047	0.046	EPSD	COSMIC	0.004	Down-regulation
AGC_NDR_LATS_LATS2_ST	P00519	ABL1	Q9NRM7	LATS2	T389	S385R	385	Missense	distal	-4	no	0.047	0.048	EPSD	COSMIC	0.004	Up-regulation
AGC_NDR_LATS_LATS2_ST	P00519	ABL1	Q9NRM7	LATS2	T389	T389A	389	Missense	central	0	yes	0.047	0.000	EPSD	COSMIC	0.004	Loss
AGC_NDR_LATS_LATS2_ST	P00519	ABL1	Q9NRM7	LATS2	T389	D391N	391	Missense	proximal	2	no	0.047	0.046	EPSD	COSMIC	0.004	Down-regulation
AGC_NDR_LATS_LATS2_ST	P00519	ABL1	Q9NRM7	LATS2	T389	G390W	390	Missense	proximal	1	no	0.047	0.046	EPSD	COSMIC	0.004	Down-regulation
AGC_NDR_LATS_LATS2_ST	P00519	ABL1	Q9NRM7	LATS2	S569	R574Q	574	Missense	distal	5	no	0.007	0.008	EPSD	COSMIC	0.004	Up-regulation
AGC_NDR_LATS_LATS2_ST	P00519	ABL1	Q9NRM7	LATS2	S569	H564Y	564	Missense	distal	-5	no	0.007	-0.004	EPSD	COSMIC	0.004	Loss
AGC_NDR_LATS_LATS2_ST	P00519	ABL1	Q9NRM7	LATS2	S601	A602T	602	Missense	proximal	1	no	0.004	0.005	EPSD	COSMIC	0.004	Up-regulation
AGC_NDR_LATS_LATS2_ST	P00519	ABL1	Q9NRM7	LATS2	S601	K596R	596	Missense	distal	-5	no	0.004	0.001	EPSD	COSMIC	0.004	Loss
AGC_NDR_LATS_LATS2_ST	P00519	ABL1	Q9NRM7	LATS2	S619	K616R	616	Missense	distal	-3	no	-0.001	0.048	EPSD	COSMIC	0.004	Gain
AGC_NDR_LATS_LATS2_ST	P00519	ABL1	Q9NRM7	LATS2	S620	G626S	626	Missense	distal	6	no	0.046	0.047	EPSD	COSMIC	0.004	Up-regulation
AGC_NDR_LATS_LATS2_ST	P00519	ABL1	Q9NRM7	LATS2	S620	K616R	616	Missense	distal	-4	no	0.046	0.047	EPSD	COSMIC	0.004	Up-regulation
AGC_NDR_LATS_LATS2_ST	P00519	ABL1	Q9NRM7	LATS2	T700	G706V	706	Missense	distal	6	no	0.050	0.051	EPSD	COSMIC	0.004	Up-regulation
AGC_NDR_LATS_LATS2_ST	P00519	ABL1	Q9NRM7	LATS2	S718	H724R	724	Missense	distal	6	no	0.049	0.048	EPSD	COSMIC	0.004	Down-regulation
AGC_NDR_LATS_LATS2_ST	P00519	ABL1	Q9NRM7	LATS2	T729	G725S	725	Missense	distal	-4	no	0.010	0.011	EPSD	COSMIC	0.004	Up-regulation
AGC_NDR_LATS_LATS2_ST	P00519	ABL1	Q9NRM7	LATS2	T729	G725V	725	Missense	distal	-4	no	0.010	0.011	EPSD	COSMIC	0.004	Up-regulation
AGC_NDR_LATS_LATS2_ST	P00519	ABL1	Q9NRM7	LATS2	T729	T729M	729	Missense	central	0	yes	0.010	0.000	EPSD	COSMIC	0.004	Loss
AGC_NDR_LATS_LATS2_ST	P00519	ABL1	Q9NRM7	LATS2	T729	H724R	724	Missense	distal	-5	no	0.010	-0.002	EPSD	COSMIC	0.004	Loss
AGC_NDR_LATS_LATS2_ST	P00519	ABL1	Q9NRM7	LATS2	T729	V722I	722	Missense	distal	-7	no	0.010	0.011	EPSD	COSMIC	0.004	Up-regulation
AGC_NDR_LATS_LATS2_ST	P00519	ABL1	Q9NRM7	LATS2	T735	R732G	732	Missense	distal	-3	no	0.047	-0.004	EPSD	COSMIC	0.004	Loss
AGC_NDR_LATS_LATS2_ST	P00519	ABL1	Q9NRM7	LATS2	T735	R732S	732	Missense	distal	-3	no	0.047	-0.005	EPSD	COSMIC	0.004	Loss
AGC_NDR_LATS_LATS2_ST	P00519	ABL1	Q9NRM7	LATS2	T823	R820W	820	Missense	distal	-3	no	0.049	0.002	EPSD	COSMIC;CCLE	0.004	Loss
AGC_NDR_LATS_LATS2_ST	P00519	ABL1	Q9NRM7	LATS2	S840	G837R	837	Missense	distal	-3	no	-0.003	0.048	EPSD	COSMIC	0.004	Gain
AGC_NDR_LATS_LATS2_ST	P00519	ABL1	Q9NRM7	LATS2	T844	G837R	837	Missense	distal	-7	no	0.005	0.004	EPSD	COSMIC	0.004	Down-regulation
AGC_NDR_LATS_LATS2_ST	P00519	ABL1	Q9NRM7	LATS2	T844	G839S	839	Missense	distal	-5	no	0.005	0.004	EPSD	COSMIC	0.004	Down-regulation
AGC_NDR_LATS_LATS2_ST	P00519	ABL1	Q9NRM7	LATS2	S919	G924E	924	Missense	distal	5	no	0.003	0.004	EPSD	COSMIC	0.004	Gain
AGC_NDR_LATS_LATS2_ST	Q8NHZ8	CDC26	Q9NRM7	LATS2	T7	R4Q	4	Missense	distal	-3	no	0.050	0.001	PhosphoSitePlus	COSMIC	0.004	Loss
AGC_NDR_LATS_LATS2_ST	P46937	YAP1	Q9NRM7	LATS2	S105	K102R	102	Missense	distal	-3	no	-0.002	0.048	EPSD	COSMIC	0.004	Gain
AGC_NDR_LATS_LATS2_ST	P46937	YAP1	Q9NRM7	LATS2	S109	R106G	106	Missense	distal	-3	no	0.061	0.009	EPSD;PhosphoSitePlus	COSMIC	0.004	Down-regulation
AGC_NDR_LATS_LATS2_ST	P46937	YAP1	Q9NRM7	LATS2	S127	L132R	132	Missense	distal	5	no	0.064	0.063	EPSD;PhosphoSitePlus	COSMIC	0.004	Down-regulation
AGC_NDR_LATS_LATS2_ST	P46937	YAP1	Q9NRM7	LATS2	S127	S127F	127	Missense	central	0	yes	0.064	0.000	EPSD;PhosphoSitePlus	COSMIC	0.004	Loss
AGC_NDR_LATS_LATS2_ST	P46937	YAP1	Q9NRM7	LATS2	S131	L132R	132	Missense	proximal	1	no	0.011	0.012	EPSD	COSMIC	0.004	Up-regulation
AGC_NDR_LATS_LATS2_ST	P46937	YAP1	Q9NRM7	LATS2	S131	Q133H	133	Missense	proximal	2	no	0.011	0.012	EPSD	COSMIC	0.004	Up-regulation
AGC_NDR_LATS_LATS2_ST	P46937	YAP1	Q9NRM7	LATS2	S138	Q133H	133	Missense	distal	-5	no	0.001	0.012	EPSD	COSMIC	0.004	Gain
AGC_NDR_LATS_LATS2_ST	P46937	YAP1	Q9NRM7	LATS2	S164	E166G	166	Missense	proximal	2	no	0.064	0.065	EPSD;PhosphoSitePlus	COSMIC	0.004	Up-regulation
AGC_NDR_LATS_LATS2_ST	P46937	YAP1	Q9NRM7	LATS2	T378	T378I	378	Missense	central	0	yes	0.047	0.000	EPSD	COSMIC	0.004	Loss
AGC_NDR_LATS_LATS2_ST	P46937	YAP1	Q9NRM7	LATS2	T378	D383G	383	Missense	distal	5	no	0.047	0.046	EPSD	COSMIC	0.004	Down-regulation
AGC_NDR_LATS_LATS2_ST	P46937	YAP1	Q9NRM7	LATS2	T378	T378M	378	Missense	central	0	yes	0.047	0.000	EPSD	COSMIC	0.004	Loss
AGC_NDR_LATS_LATS2_ST	P46937	YAP1	Q9NRM7	LATS2	S388	D383H	383	Missense	distal	-5	no	0.000	0.011	EPSD	COSMIC	0.004	Gain
AGC_NDR_LATS_LATS2_ST	P46937	YAP1	Q9NRM7	LATS2	S397	D399G	399	Missense	proximal	2	no	0.061	0.062	EPSD	COSMIC	0.004	Up-regulation
AGC_NDR_LATS_LATS2_ST	P46937	YAP1	Q9NRM7	LATS2	S397	T390I	390	Missense	distal	-7	no	0.061	0.062	EPSD	COSMIC	0.004	Up-regulation
AGC_NDR_LATS_LATS2_ST	P46937	YAP1	Q9NRM7	LATS2	S419	F416L	416	Missense	distal	-3	no	0.005	0.003	EPSD	COSMIC	0.004	Loss
AGC_NDR_LATS_LATS2_ST	P46937	YAP1	Q9NRM7	LATS2	S432	D427H	427	Missense	distal	-5	no	0.003	0.013	EPSD	COSMIC	0.004	Gain
AGC_NDR_LATS_LATS2_ST	Q9Y2J4	AMOTL2	Q9NRM7	LATS2	S157	H154Y	154	Missense	distal	-3	no	0.014	0.015	EPSD	COSMIC	0.004	Up-regulation
AGC_NDR_LATS_LATS2_ST	Q9Y2J4	AMOTL2	Q9NRM7	LATS2	S159	R156P	156	Missense	distal	-3	no	0.062	0.009	PhosphoSitePlus	COSMIC	0.004	Down-regulation
AGC_NDR_LATS_LATS2_ST	Q9Y2J4	AMOTL2	Q9NRM7	LATS2	S159	H154Y	154	Missense	distal	-5	no	0.062	0.051	PhosphoSitePlus	COSMIC	0.004	Down-regulation
AGC_NDR_LATS_LATS2_ST	Q9Y2J4	AMOTL2	Q9NRM7	LATS2	S159	R156C	156	Missense	distal	-3	no	0.062	0.014	PhosphoSitePlus	COSMIC	0.004	Down-regulation
AGC_NDR_LATS_LATS2_ST	Q9Y2J4	AMOTL2	Q9NRM7	LATS2	S159	R156H	156	Missense	distal	-3	no	0.062	0.012	PhosphoSitePlus	COSMIC	0.004	Down-regulation
AGC_NDR_LATS_LATS2_ST	Q9Y2J4	AMOTL2	Q9NRM7	LATS2	S176	R173Q	173	Missense	distal	-3	no	0.051	0.002	EPSD	COSMIC	0.004	Loss
AGC_NDR_LATS_LATS2_ST	Q9Y2J4	AMOTL2	Q9NRM7	LATS2	T512	E507K	507	Missense	distal	-5	no	0.050	0.052	EPSD	COSMIC	0.004	Up-regulation
AGC_NDR_LATS_LATS2_ST	Q9Y2J4	AMOTL2	Q9NRM7	LATS2	T597	S602F	602	Missense	distal	5	no	0.049	0.048	EPSD	COSMIC	0.004	Down-regulation
AGC_NDR_LATS_LATS2_ST	Q9Y2J4	AMOTL2	Q9NRM7	LATS2	S606	S606L	606	Missense	central	0	yes	0.009	0.000	EPSD	COSMIC	0.004	Loss
AGC_NDR_LATS_LATS2_ST	Q9Y2J4	AMOTL2	Q9NRM7	LATS2	S661	R663Q	663	Missense	proximal	2	no	0.004	0.005	EPSD	COSMIC	0.004	Up-regulation
AGC_NDR_LATS_LATS2_ST	Q9Y2J4	AMOTL2	Q9NRM7	LATS2	S723	D725G	725	Missense	proximal	2	no	0.010	0.011	EPSD	COSMIC	0.004	Up-regulation
AGC_NDR_LATS_LATS2_ST	Q9Y2J4	AMOTL2	Q9NRM7	LATS2	S759	R756K	756	Missense	distal	-3	no	0.051	0.002	EPSD	COSMIC	0.004	Loss
AGC_NDR_LATS_LATS2_ST	Q9Y2J4	AMOTL2	Q9NRM7	LATS2	S759	R756I	756	Missense	distal	-3	no	0.051	0.002	EPSD	COSMIC	0.004	Loss
AGC_NDR_LATS_LATS2_ST	Q9Y2J4	AMOTL2	Q9NRM7	LATS2	S759	R756W	756	Missense	distal	-3	no	0.051	0.004	EPSD	COSMIC	0.004	Down-regulation
AGC_NDR_LATS_LATS2_ST	P61981	YWHAG	Q9NRM7	LATS2	S64	Q68L	68	Missense	distal	4	no	0.049	0.050	EPSD	COSMIC	0.004	Up-regulation
AGC_NDR_LATS_LATS2_ST	P61981	YWHAG	Q9NRM7	LATS2	S71	K77R	77	Missense	distal	6	no	0.006	0.005	EPSD	COSMIC	0.004	Down-regulation
AGC_NDR_LATS_LATS2_ST	P61981	YWHAG	Q9NRM7	LATS2	S71	I66T	66	Missense	distal	-5	no	0.006	0.005	EPSD	COSMIC	0.004	Down-regulation
AGC_NDR_LATS_LATS2_ST	P61981	YWHAG	Q9NRM7	LATS2	S71	Q68L	68	Missense	distal	-3	no	0.006	0.005	EPSD	COSMIC	0.004	Down-regulation
AGC_NDR_LATS_LATS2_ST	P61981	YWHAG	Q9NRM7	LATS2	T139	A144V	144	Missense	distal	5	no	0.004	0.003	EPSD	COSMIC;CCLE	0.004	Loss
AGC_NDR_LATS_LATS2_ST	P61981	YWHAG	Q9NRM7	LATS2	T139	R132L	132	Missense	distal	-7	no	0.004	0.003	EPSD	COSMIC	0.004	Loss
AGC_NDR_LATS_LATS2_ST	P61981	YWHAG	Q9NRM7	LATS2	T139	A144T	144	Missense	distal	5	no	0.004	0.003	EPSD	COSMIC	0.004	Loss
AGC_NDR_LATS_LATS2_ST	P61981	YWHAG	Q9NRM7	LATS2	T139	T145M	145	Missense	distal	6	no	0.004	0.003	EPSD	COSMIC	0.004	Loss
AGC_NDR_LATS_LATS2_ST	P61981	YWHAG	Q9NRM7	LATS2	S150	R143G	143	Missense	distal	-7	no	0.003	0.004	EPSD	COSMIC	0.004	Gain
AGC_NDR_LATS_LATS2_ST	Q02241	KIF23	Q9NRM7	LATS2	S298	N291D	291	Missense	distal	-7	no	0.010	0.011	EPSD	COSMIC	0.004	Up-regulation
AGC_NDR_LATS_LATS2_ST	Q02241	KIF23	Q9NRM7	LATS2	S605	R602Q	602	Missense	distal	-3	no	0.049	0.000	EPSD	COSMIC	0.004	Loss
AGC_NDR_LATS_LATS2_ST	Q02241	KIF23	Q9NRM7	LATS2	S692	P687H	687	Missense	distal	-5	no	-0.005	0.005	EPSD	COSMIC	0.004	Gain
AGC_NDR_LATS_LATS2_ST	Q02241	KIF23	Q9NRM7	LATS2	S814	H809Q	809	Missense	distal	-5	no	0.066	0.055	PhosphoSitePlus;EPSD	COSMIC	0.004	Down-regulation
AGC_NDR_LATS_LATS2_ST	Q02241	KIF23	Q9NRM7	LATS2	S867	G869W	869	Missense	proximal	2	no	0.011	0.010	EPSD	COSMIC	0.004	Down-regulation
AGC_NDR_LATS_LATS2_ST	Q02241	KIF23	Q9NRM7	LATS2	S902	R907Q	907	Missense	distal	5	no	0.003	0.004	EPSD	COSMIC	0.004	Gain
AGC_NDR_LATS_LATS2_ST	Q02241	KIF23	Q9NRM7	LATS2	S912	A917D	917	Missense	distal	5	no	0.049	0.048	EPSD	COSMIC	0.004	Down-regulation
AGC_NDR_LATS_LATS2_ST	Q4VCS5	AMOT	Q9NRM7	LATS2	S175	S175G	175	Missense	central	0	yes	0.060	0.000	PhosphoSitePlus	COSMIC	0.004	Loss
AGC_NDR_LATS_LATS2_ST	Q4VCS5	AMOT	Q9NRM7	LATS2	S175	Q168H	168	Missense	distal	-7	no	0.060	0.059	PhosphoSitePlus	COSMIC	0.004	Down-regulation
AGC_NDR_LATS_LATS2_ST	Q4VCS5	AMOT	Q9NRM7	LATS2	S196	V194G	194	Missense	proximal	-2	no	0.007	0.008	EPSD	COSMIC	0.004	Up-regulation
AGC_NDR_LATS_LATS2_ST	Q4VCS5	AMOT	Q9NRM7	LATS2	T806	H801N	801	Missense	distal	-5	no	0.010	0.000	EPSD	COSMIC	0.004	Loss
AGC_NDR_LATS_LATS2_ST	Q4VCS5	AMOT	Q9NRM7	LATS2	S863	S863I	863	Missense	central	0	yes	0.046	0.000	EPSD	COSMIC	0.004	Loss
AGC_NDR_LATS_LATS2_ST	Q4VCS5	AMOT	Q9NRM7	LATS2	S863	R868L	868	Missense	distal	5	no	0.046	0.047	EPSD	COSMIC	0.004	Up-regulation
AGC_NDR_LATS_LATS2_ST	Q4VCS5	AMOT	Q9NRM7	LATS2	S1044	R1039H	1039	Missense	distal	-5	no	-0.003	0.009	EPSD	COSMIC	0.004	Gain
AGC_NDR_LATS_LATS2_ST	Q9GZV5	WWTR1	Q9NRM7	LATS2	S51	L48R	48	Missense	distal	-3	no	0.003	0.053	EPSD	COSMIC	0.004	Gain
AGC_NDR_LATS_LATS2_ST	Q9GZV5	WWTR1	Q9NRM7	LATS2	S66	R63C	63	Missense	distal	-3	no	0.057	0.009	EPSD	COSMIC	0.004	Down-regulation
AGC_NDR_LATS_LATS2_ST	Q9GZV5	WWTR1	Q9NRM7	LATS2	T67	S62L	62	Missense	distal	-5	no	0.003	0.004	EPSD	COSMIC	0.004	Gain
AGC_NDR_LATS_LATS2_ST	Q9GZV5	WWTR1	Q9NRM7	LATS2	S89	S89A	89	Missense	central	0	yes	0.071	0.000	PhosphoSitePlus	COSMIC	0.004	Loss
AGC_NDR_LATS_LATS2_ST	Q9GZV5	WWTR1	Q9NRM7	LATS2	S117	R114C	114	Missense	distal	-3	no	0.059	0.012	EPSD	COSMIC	0.004	Down-regulation
AGC_NDR_LATS_LATS2_ST	Q9GZV5	WWTR1	Q9NRM7	LATS2	S117	D119G	119	Missense	proximal	2	no	0.059	0.060	EPSD	COSMIC	0.004	Up-regulation
AGC_NDR_LATS_LATS2_ST	Q9GZV5	WWTR1	Q9NRM7	LATS2	S117	R114H	114	Missense	distal	-3	no	0.059	0.010	EPSD	COSMIC;CCLE	0.004	Down-regulation
AGC_NDR_LATS_LATS2_ST	Q9GZV5	WWTR1	Q9NRM7	LATS2	S174	A171V	171	Missense	distal	-3	no	0.009	0.010	EPSD	COSMIC	0.004	Up-regulation
AGC_NDR_LATS_LATS2_ST	O95863	SNAI1	Q9NRM7	LATS2	T177	T177M	177	Missense	central	0	yes	0.059	0.000	EPSD	COSMIC	0.004	Loss
AGC_NDR_LATS_LATS2_ST	O95863	SNAI1	Q9NRM7	LATS2	S231	H226Y	226	Missense	distal	-5	no	0.010	-0.001	EPSD	COSMIC	0.004	Loss
AGC_NDR_LATS_LATS2_ST	O95863	SNAI1	Q9NRM7	LATS2	S246	H252Y	252	Missense	distal	6	no	0.049	0.048	EPSD	COSMIC	0.004	Down-regulation
AGC_NDR_LATS_LATS2_ST	O95863	SNAI1	Q9NRM7	LATS2	S246	S246F	246	Missense	central	0	yes	0.049	0.000	EPSD	COSMIC	0.004	Loss
Other_CAMKK_CAMKK-Meta_CAMKK2_ST	Q96EB6	SIRT1	Q96RR4	CAMKK2	S169	E165D	165	Missense	distal	-4	no	16.224	16.235	EPSD	COSMIC	15.642	Up-regulation
Other_CAMKK_CAMKK-Meta_CAMKK2_ST	Q96EB6	SIRT1	Q96RR4	CAMKK2	T530	E536V	536	Missense	distal	6	no	16.458	16.475	EPSD	COSMIC	15.642	Up-regulation
Other_CAMKK_CAMKK-Meta_CAMKK2_ST	Q96EB6	SIRT1	Q96RR4	CAMKK2	S535	E542Q	542	Missense	distal	7	no	16.570	16.544	EPSD	COSMIC	15.642	Down-regulation
Other_CAMKK_CAMKK-Meta_CAMKK2_ST	Q96EB6	SIRT1	Q96RR4	CAMKK2	S535	E536V	536	Missense	proximal	1	no	16.570	12.335	EPSD	COSMIC	15.642	Loss
Other_CAMKK_CAMKK-Meta_CAMKK2_ST	Q96EB6	SIRT1	Q96RR4	CAMKK2	T544	E542Q	542	Missense	proximal	-2	no	24.552	24.444	EPSD	COSMIC	15.642	Down-regulation
Other_CAMKK_CAMKK-Meta_CAMKK2_ST	Q96EB6	SIRT1	Q96RR4	CAMKK2	T544	S549C	549	Missense	distal	5	no	24.552	19.907	EPSD	COSMIC	15.642	Down-regulation
Other_CAMKK_CAMKK-Meta_CAMKK2_ST	Q96EB6	SIRT1	Q96RR4	CAMKK2	S545	E542Q	542	Missense	distal	-3	no	22.282	22.307	EPSD	COSMIC	15.642	Up-regulation
Other_CAMKK_CAMKK-Meta_CAMKK2_ST	Q96EB6	SIRT1	Q96RR4	CAMKK2	S545	S549C	549	Missense	distal	4	no	22.282	19.269	EPSD	COSMIC	15.642	Down-regulation
Other_CAMKK_CAMKK-Meta_CAMKK2_ST	Q96RR4	CAMKK2	Q96RR4	CAMKK2	T85	V81A	81	Missense	distal	-4	no	34.513	34.500	PhosphoSitePlus	COSMIC	15.642	Down-regulation
Other_CAMKK_CAMKK-Meta_CAMKK2_ST	Q96RR4	CAMKK2	Q96RR4	CAMKK2	T85	R91W	91	Missense	distal	6	no	34.513	34.516	PhosphoSitePlus	COSMIC;CCLE	15.642	Up-regulation
Other_CAMKK_CAMKK-Meta_CAMKK2_ST	Q96RR4	CAMKK2	Q96RR4	CAMKK2	T85	G87R	87	Missense	proximal	2	no	34.513	32.596	PhosphoSitePlus	COSMIC	15.642	Down-regulation
Other_CAMKK_CAMKK-Meta_CAMKK2_ST	Q96RR4	CAMKK2	Q96RR4	CAMKK2	S129	P127L	127	Missense	proximal	-2	no	18.509	18.980	EPSD	COSMIC;CCLE	15.642	Up-regulation
Other_CAMKK_CAMKK-Meta_CAMKK2_ST	Q96RR4	CAMKK2	Q96RR4	CAMKK2	S132	P138L	138	Missense	distal	6	no	20.166	20.165	EPSD	COSMIC	15.642	Down-regulation
Other_CAMKK_CAMKK-Meta_CAMKK2_ST	Q96RR4	CAMKK2	Q96RR4	CAMKK2	S132	P127L	127	Missense	distal	-5	no	20.166	18.626	EPSD	COSMIC;CCLE	15.642	Down-regulation
Other_CAMKK_CAMKK-Meta_CAMKK2_ST	Q96RR4	CAMKK2	Q96RR4	CAMKK2	T350	L344F	344	Missense	distal	-6	no	18.401	18.499	EPSD	COSMIC	15.642	Up-regulation
Other_CAMKK_CAMKK-Meta_CAMKK2_ST	Q96RR4	CAMKK2	Q96RR4	CAMKK2	S511	R505C	505	Missense	distal	-6	no	15.890	15.845	EPSD	COSMIC	15.642	Down-regulation
Other_CAMKK_CAMKK-Meta_CAMKK2_ST	Q13131	PRKAA1	Q96RR4	CAMKK2	T355	F351L	351	Missense	distal	-4	no	15.719	15.748	EPSD	COSMIC	15.642	Up-regulation
Other_CAMKK_CAMKK-Meta_CAMKK2_ST	Q13131	PRKAA1	Q96RR4	CAMKK2	T355	A354T	354	Missense	proximal	-1	no	15.719	15.573	EPSD	COSMIC	15.642	Loss
Other_CAMKK_CAMKK-Meta_CAMKK2_ST	Q13131	PRKAA1	Q96RR4	CAMKK2	T355	D350N	350	Missense	distal	-5	no	15.719	14.095	EPSD	COSMIC	15.642	Loss
Other_CAMKK_CAMKK-Meta_CAMKK2_ST	Q13131	PRKAA1	Q96RR4	CAMKK2	S486	A484D	484	Missense	proximal	-2	no	17.751	17.169	EPSD	COSMIC	15.642	Down-regulation
Other_CAMKK_CAMKK-Meta_CAMKK2_ST	Q13131	PRKAA1	Q96RR4	CAMKK2	S502	R505G	505	Missense	distal	3	no	14.189	18.178	EPSD	COSMIC	15.642	Gain
Other_CAMKK_CAMKK-Meta_CAMKK2_ST	Q13131	PRKAA1	Q96RR4	CAMKK2	T522	S524F	524	Missense	proximal	2	no	16.398	15.928	EPSD	COSMIC	15.642	Down-regulation
Other_CAMKK_CAMKK-Meta_CAMKK2_ST	Q13131	PRKAA1	Q96RR4	CAMKK2	S527	S524F	524	Missense	distal	-3	no	22.652	22.657	EPSD	COSMIC	15.642	Up-regulation
Other_CAMKK_CAMKK-Meta_CAMKK2_ST	Q13131	PRKAA1	Q96RR4	CAMKK2	S527	S531F	531	Missense	distal	4	no	22.652	20.059	EPSD	COSMIC	15.642	Down-regulation
Other_CAMKK_CAMKK-Meta_CAMKK2_ST	Q13131	PRKAA1	Q96RR4	CAMKK2	T536	P539S	539	Missense	distal	3	no	19.204	21.259	EPSD	COSMIC	15.642	Up-regulation
Other_CAMKK_CAMKK-Meta_CAMKK2_ST	Q13131	PRKAA1	Q96RR4	CAMKK2	T536	P539T	539	Missense	distal	3	no	19.204	19.368	EPSD	COSMIC	15.642	Up-regulation
Other_CAMKK_CAMKK-Meta_CAMKK2_ST	Q13131	PRKAA1	Q96RR4	CAMKK2	T536	S531F	531	Missense	distal	-5	no	19.204	16.590	EPSD	COSMIC	15.642	Down-regulation
Other_CAMKK_CAMKK-Meta_CAMKK2_ST	P54646	PRKAA2	Q96RR4	CAMKK2	T172	R171K	171	Missense	proximal	-1	no	44.267	44.285	PhosphoSitePlus	COSMIC	15.642	Up-regulation
Other_CAMKK_CAMKK-Meta_CAMKK2_ST	P54646	PRKAA2	Q96RR4	CAMKK2	T172	C174Y	174	Missense	proximal	2	no	44.267	43.107	PhosphoSitePlus	COSMIC	15.642	Down-regulation
Other_CAMKK_CAMKK-Meta_CAMKK2_ST	P54646	PRKAA2	Q96RR4	CAMKK2	T172	G167C	167	Missense	distal	-5	no	44.267	42.010	PhosphoSitePlus	COSMIC	15.642	Down-regulation
Other_CAMKK_CAMKK-Meta_CAMKK2_ST	P54646	PRKAA2	Q96RR4	CAMKK2	S173	R171K	171	Missense	proximal	-2	no	16.125	14.997	EPSD	COSMIC	15.642	Loss
Other_CAMKK_CAMKK-Meta_CAMKK2_ST	P54646	PRKAA2	Q96RR4	CAMKK2	S173	C174Y	174	Missense	proximal	1	no	16.125	16.572	EPSD	COSMIC	15.642	Up-regulation
Other_CAMKK_CAMKK-Meta_CAMKK2_ST	P54646	PRKAA2	Q96RR4	CAMKK2	S173	G167C	167	Missense	distal	-6	no	16.125	16.080	EPSD	COSMIC	15.642	Down-regulation
Other_CAMKK_CAMKK-Meta_CAMKK2_ST	P54646	PRKAA2	Q96RR4	CAMKK2	S344	Y341S	341	Missense	distal	-3	no	22.143	22.138	EPSD	COSMIC	15.642	Down-regulation
Other_CAMKK_CAMKK-Meta_CAMKK2_ST	P54646	PRKAA2	Q96RR4	CAMKK2	S344	A343S	343	Missense	proximal	-1	no	22.143	22.156	EPSD	COSMIC;GDSC;CCLE	15.642	Up-regulation
Other_CAMKK_CAMKK-Meta_CAMKK2_ST	P54646	PRKAA2	Q96RR4	CAMKK2	S345	Y341S	341	Missense	distal	-4	no	20.432	20.412	EPSD	COSMIC	15.642	Down-regulation
Other_CAMKK_CAMKK-Meta_CAMKK2_ST	P54646	PRKAA2	Q96RR4	CAMKK2	S345	A343S	343	Missense	proximal	-2	no	20.432	18.670	EPSD	COSMIC;GDSC;CCLE	15.642	Down-regulation
Other_CAMKK_CAMKK-Meta_CAMKK2_ST	P54646	PRKAA2	Q96RR4	CAMKK2	S350	A343S	343	Missense	distal	-7	no	17.660	18.229	EPSD	COSMIC;GDSC;CCLE	15.642	Up-regulation
Other_CAMKK_CAMKK-Meta_CAMKK2_ST	P54646	PRKAA2	Q96RR4	CAMKK2	S350	D353N	353	Missense	distal	3	no	17.660	16.175	EPSD	COSMIC	15.642	Down-regulation
Other_CAMKK_CAMKK-Meta_CAMKK2_ST	P54646	PRKAA2	Q96RR4	CAMKK2	S350	S355G	355	Missense	distal	5	no	17.660	11.280	EPSD	COSMIC	15.642	Loss
Other_CAMKK_CAMKK-Meta_CAMKK2_ST	P54646	PRKAA2	Q96RR4	CAMKK2	S350	S355T	355	Missense	distal	5	no	17.660	14.718	EPSD	COSMIC	15.642	Loss
Other_CAMKK_CAMKK-Meta_CAMKK2_ST	P54646	PRKAA2	Q96RR4	CAMKK2	S481	E475K	475	Missense	distal	-6	no	21.659	21.691	EPSD	COSMIC	15.642	Up-regulation
Other_CAMKK_CAMKK-Meta_CAMKK2_ST	P54646	PRKAA2	Q96RR4	CAMKK2	S481	Q479H	479	Missense	proximal	-2	no	21.659	21.978	EPSD	COSMIC	15.642	Up-regulation
Other_CAMKK_CAMKK-Meta_CAMKK2_ST	P54646	PRKAA2	Q96RR4	CAMKK2	S481	E478K	478	Missense	distal	-3	no	21.659	21.718	EPSD	COSMIC	15.642	Up-regulation
Other_CAMKK_CAMKK-Meta_CAMKK2_ST	P54646	PRKAA2	Q96RR4	CAMKK2	S501	S501N	501	Missense	central	0	yes	16.024	0.000	EPSD	COSMIC	15.642	Loss
Other_CAMKK_CAMKK-Meta_CAMKK2_ST	P31749	AKT1	Q96RR4	CAMKK2	S122	E115K	115	Missense	distal	-7	no	17.841	16.914	EPSD	COSMIC	15.642	Down-regulation
Other_CAMKK_CAMKK-Meta_CAMKK2_ST	P31749	AKT1	Q96RR4	CAMKK2	S122	G123D	123	Missense	proximal	1	no	17.841	17.187	EPSD	COSMIC	15.642	Down-regulation
Other_CAMKK_CAMKK-Meta_CAMKK2_ST	P31749	AKT1	Q96RR4	CAMKK2	S122	D127N	127	Missense	distal	5	no	17.841	10.740	EPSD	COSMIC	15.642	Loss
Other_CAMKK_CAMKK-Meta_CAMKK2_ST	P31749	AKT1	Q96RR4	CAMKK2	S122	E116D	116	Missense	distal	-6	no	17.841	17.900	EPSD	COSMIC	15.642	Up-regulation
Other_CAMKK_CAMKK-Meta_CAMKK2_ST	P31749	AKT1	Q96RR4	CAMKK2	S129	G123D	123	Missense	distal	-6	no	18.956	19.020	EPSD	COSMIC	15.642	Up-regulation
Other_CAMKK_CAMKK-Meta_CAMKK2_ST	P31749	AKT1	Q96RR4	CAMKK2	S129	D127N	127	Missense	proximal	-2	no	18.956	18.532	EPSD	COSMIC	15.642	Down-regulation
Other_CAMKK_CAMKK-Meta_CAMKK2_ST	P31749	AKT1	Q96RR4	CAMKK2	S129	E133Q	133	Missense	distal	4	no	18.956	19.411	EPSD	COSMIC	15.642	Up-regulation
Other_CAMKK_CAMKK-Meta_CAMKK2_ST	P31749	AKT1	Q96RR4	CAMKK2	S129	G130R	130	Missense	proximal	1	no	18.956	16.297	EPSD	COSMIC	15.642	Down-regulation
Other_CAMKK_CAMKK-Meta_CAMKK2_ST	P31749	AKT1	Q96RR4	CAMKK2	S129	E135Q	135	Missense	distal	6	no	18.956	18.948	EPSD	COSMIC	15.642	Down-regulation
Other_CAMKK_CAMKK-Meta_CAMKK2_ST	P31749	AKT1	Q96RR4	CAMKK2	T308	M306T	306	Missense	proximal	-2	no	41.175	39.706	PhosphoSitePlus	COSMIC	15.642	Down-regulation
Other_CAMKK_CAMKK-Meta_CAMKK2_ST	P31749	AKT1	Q96RR4	CAMKK2	T308	M306L	306	Missense	proximal	-2	no	41.175	40.718	PhosphoSitePlus	COSMIC	15.642	Down-regulation
Other_CAMKK_CAMKK-Meta_CAMKK2_ST	P31749	AKT1	Q96RR4	CAMKK2	T308	M306I	306	Missense	proximal	-2	no	41.175	40.623	PhosphoSitePlus	COSMIC	15.642	Down-regulation
Other_CAMKK_CAMKK-Meta_CAMKK2_ST	P31749	AKT1	Q96RR4	CAMKK2	T308	T312I	312	Missense	distal	4	no	41.175	38.978	PhosphoSitePlus	COSMIC	15.642	Down-regulation
Other_CAMKK_CAMKK-Meta_CAMKK2_ST	P31749	AKT1	Q96RR4	CAMKK2	T308	G303S	303	Missense	distal	-5	no	41.175	39.612	PhosphoSitePlus	COSMIC	15.642	Down-regulation
Other_CAMKK_CAMKK-Meta_CAMKK2_ST	P31749	AKT1	Q96RR4	CAMKK2	T450	P452L	452	Missense	proximal	2	no	15.693	13.660	EPSD	COSMIC	15.642	Loss
Other_CAMKK_CAMKK-Meta_CAMKK2_ST	P31749	AKT1	Q96RR4	CAMKK2	T450	M446I	446	Missense	distal	-4	no	15.693	15.684	EPSD	COSMIC	15.642	Down-regulation
Other_CAMKK_CAMKK-Meta_CAMKK2_ST	P31749	AKT1	Q96RR4	CAMKK2	T450	I447F	447	Missense	distal	-3	no	15.693	15.704	EPSD	COSMIC	15.642	Up-regulation
Other_CAMKK_CAMKK-Meta_CAMKK2_ST	P31749	AKT1	Q96RR4	CAMKK2	T450	T443M	443	Missense	distal	-7	no	15.693	15.089	EPSD	COSMIC	15.642	Loss
Other_CAMKK_CAMKK-Meta_CAMKK2_ST	P31749	AKT1	Q96RR4	CAMKK2	S457	E464K	464	Missense	distal	7	no	15.842	15.819	EPSD	COSMIC	15.642	Down-regulation
Other_CAMKK_CAMKK-Meta_CAMKK2_ST	P31749	AKT1	Q96RR4	CAMKK2	S457	P452L	452	Missense	distal	-5	no	15.842	14.302	EPSD	COSMIC	15.642	Loss
Other_CAMKK_CAMKK-Meta_CAMKK2_ST	P31749	AKT1	Q96RR4	CAMKK2	S457	C460S	460	Missense	distal	3	no	15.842	16.976	EPSD	COSMIC	15.642	Up-regulation
Other_CAMKK_CAMKK-Meta_CAMKK2_ST	P31749	AKT1	Q96RR4	CAMKK2	S457	M458I	458	Missense	proximal	1	no	15.842	16.401	EPSD	COSMIC	15.642	Up-regulation
TK_FGFR_FGFR1_Y	P11362	FGFR1	P11362	FGFR1	Y154	R148C	148	Missense	distal	-6	no	7.873	7.874	EPSD;PhosphoSitePlus	COSMIC	5.471	Up-regulation
TK_FGFR_FGFR1_Y	P11362	FGFR1	P11362	FGFR1	Y154	R148H	148	Missense	distal	-6	no	7.873	7.817	EPSD;PhosphoSitePlus	COSMIC	5.471	Down-regulation
TK_FGFR_FGFR1_Y	P11362	FGFR1	P11362	FGFR1	Y154	E159G	159	Missense	distal	5	no	7.873	8.026	EPSD;PhosphoSitePlus	COSMIC	5.471	Up-regulation
TK_FGFR_FGFR1_Y	P11362	FGFR1	P11362	FGFR1	Y154	V151I	151	Missense	distal	-3	no	7.873	9.446	EPSD;PhosphoSitePlus	COSMIC	5.471	Up-regulation
TK_FGFR_FGFR1_Y	P11362	FGFR1	P11362	FGFR1	Y154	P150L	150	Missense	distal	-4	no	7.873	8.218	EPSD;PhosphoSitePlus	COSMIC;GDSC	5.471	Up-regulation
TK_FGFR_FGFR1_Y	P11362	FGFR1	P11362	FGFR1	Y280	P283S	283	Missense	distal	3	no	8.681	9.978	EPSD	COSMIC	5.471	Up-regulation
TK_FGFR_FGFR1_Y	P11362	FGFR1	P11362	FGFR1	Y280	C277Y	277	Missense	distal	-3	no	8.681	8.884	EPSD	COSMIC	5.471	Up-regulation
TK_FGFR_FGFR1_Y	P11362	FGFR1	P11362	FGFR1	Y280	P283L	283	Missense	distal	3	no	8.681	8.355	EPSD	COSMIC	5.471	Down-regulation
TK_FGFR_FGFR1_Y	P11362	FGFR1	P11362	FGFR1	Y280	D282E	282	Missense	proximal	2	no	8.681	8.535	EPSD	COSMIC	5.471	Down-regulation
TK_FGFR_FGFR1_Y	P11362	FGFR1	P11362	FGFR1	Y280	E274K	274	Missense	distal	-6	no	8.681	8.644	EPSD	COSMIC	5.471	Down-regulation
TK_FGFR_FGFR1_Y	P11362	FGFR1	P11362	FGFR1	Y280	P283T	283	Missense	distal	3	no	8.681	8.927	EPSD	COSMIC	5.471	Up-regulation
TK_FGFR_FGFR1_Y	P11362	FGFR1	P11362	FGFR1	Y280	V279M	279	Missense	proximal	-1	no	8.681	9.055	EPSD	COSMIC	5.471	Up-regulation
TK_FGFR_FGFR1_Y	P11362	FGFR1	P11362	FGFR1	Y307	Q309K	309	Missense	proximal	2	no	8.158	8.022	EPSD	COSMIC	5.471	Down-regulation
TK_FGFR_FGFR1_Y	P11362	FGFR1	P11362	FGFR1	Y307	T313I	313	Missense	distal	6	no	8.158	8.151	EPSD	COSMIC	5.471	Down-regulation
TK_FGFR_FGFR1_Y	P11362	FGFR1	P11362	FGFR1	Y307	Y307H	307	Missense	central	0	yes	8.158	0.000	EPSD	COSMIC	5.471	Loss
TK_FGFR_FGFR1_Y	P11362	FGFR1	P11362	FGFR1	Y307	I310V	310	Missense	distal	3	no	8.158	7.716	EPSD	COSMIC	5.471	Down-regulation
TK_FGFR_FGFR1_Y	P11362	FGFR1	P11362	FGFR1	Y307	G301C	301	Missense	distal	-6	no	8.158	8.193	EPSD	COSMIC	5.471	Up-regulation
TK_FGFR_FGFR1_Y	P11362	FGFR1	P11362	FGFR1	Y463	R470P	470	Missense	distal	7	no	8.511	8.231	EPSD;PhosphoSitePlus	COSMIC	5.471	Down-regulation
TK_FGFR_FGFR1_Y	P11362	FGFR1	P11362	FGFR1	Y463	E462Q	462	Missense	proximal	-1	no	8.511	8.276	EPSD;PhosphoSitePlus	COSMIC	5.471	Down-regulation
TK_FGFR_FGFR1_Y	P11362	FGFR1	P11362	FGFR1	Y463	G459R	459	Missense	distal	-4	no	8.511	8.751	EPSD;PhosphoSitePlus	COSMIC	5.471	Up-regulation
TK_FGFR_FGFR1_Y	P11362	FGFR1	P11362	FGFR1	Y463	E467K	467	Missense	distal	4	no	8.511	8.124	EPSD;PhosphoSitePlus	COSMIC	5.471	Down-regulation
TK_FGFR_FGFR1_Y	P11362	FGFR1	P11362	FGFR1	Y463	R470L	470	Missense	distal	7	no	8.511	8.677	EPSD;PhosphoSitePlus	COSMIC	5.471	Up-regulation
TK_FGFR_FGFR1_Y	P11362	FGFR1	P11362	FGFR1	Y463	M456I	456	Missense	distal	-7	no	8.511	8.559	EPSD;PhosphoSitePlus	COSMIC;GDSC	5.471	Up-regulation
TK_FGFR_FGFR1_Y	P11362	FGFR1	P11362	FGFR1	Y463	P466L	466	Missense	distal	3	no	8.511	8.184	EPSD;PhosphoSitePlus	COSMIC	5.471	Down-regulation
TK_FGFR_FGFR1_Y	P11362	FGFR1	P11362	FGFR1	Y463	R470C	470	Missense	distal	7	no	8.511	8.345	EPSD;PhosphoSitePlus	COSMIC	5.471	Down-regulation
TK_FGFR_FGFR1_Y	P11362	FGFR1	P11362	FGFR1	Y463	L457R	457	Missense	distal	-6	no	8.511	8.505	EPSD;PhosphoSitePlus	COSMIC	5.471	Down-regulation
TK_FGFR_FGFR1_Y	P11362	FGFR1	P11362	FGFR1	Y583	E582G	582	Missense	proximal	-1	no	7.952	6.463	EPSD;PhosphoSitePlus	COSMIC	5.471	Down-regulation
TK_FGFR_FGFR1_Y	P11362	FGFR1	P11362	FGFR1	Y583	E582K	582	Missense	proximal	-1	no	7.952	7.556	EPSD;PhosphoSitePlus	COSMIC	5.471	Down-regulation
TK_FGFR_FGFR1_Y	P11362	FGFR1	P11362	FGFR1	Y583	R577W	577	Missense	distal	-6	no	7.952	7.906	EPSD;PhosphoSitePlus	COSMIC	5.471	Down-regulation
TK_FGFR_FGFR1_Y	P11362	FGFR1	P11362	FGFR1	Y583	R576W	576	Missense	distal	-7	no	7.952	7.990	EPSD;PhosphoSitePlus	COSMIC	5.471	Up-regulation
TK_FGFR_FGFR1_Y	P11362	FGFR1	P11362	FGFR1	Y583	S588T	588	Missense	distal	5	no	7.952	7.356	EPSD;PhosphoSitePlus	COSMIC	5.471	Down-regulation
TK_FGFR_FGFR1_Y	P11362	FGFR1	P11362	FGFR1	Y583	R576Q	576	Missense	distal	-7	no	7.952	7.951	EPSD;PhosphoSitePlus	COSMIC	5.471	Down-regulation
TK_FGFR_FGFR1_Y	P11362	FGFR1	P11362	FGFR1	Y583	P587H	587	Missense	distal	4	no	7.952	7.408	EPSD;PhosphoSitePlus	COSMIC	5.471	Down-regulation
TK_FGFR_FGFR1_Y	P11362	FGFR1	P11362	FGFR1	Y585	E582G	582	Missense	distal	-3	no	8.995	10.324	EPSD;PhosphoSitePlus	COSMIC	5.471	Up-regulation
TK_FGFR_FGFR1_Y	P11362	FGFR1	P11362	FGFR1	Y585	E582K	582	Missense	distal	-3	no	8.995	9.807	EPSD;PhosphoSitePlus	COSMIC	5.471	Up-regulation
TK_FGFR_FGFR1_Y	P11362	FGFR1	P11362	FGFR1	Y585	E592G	592	Missense	distal	7	no	8.995	7.536	EPSD;PhosphoSitePlus	COSMIC;GDSC;CCLE	5.471	Down-regulation
TK_FGFR_FGFR1_Y	P11362	FGFR1	P11362	FGFR1	Y585	P591Q	591	Missense	distal	6	no	8.995	8.999	EPSD;PhosphoSitePlus	COSMIC	5.471	Up-regulation
TK_FGFR_FGFR1_Y	P11362	FGFR1	P11362	FGFR1	Y585	S588T	588	Missense	distal	3	no	8.995	7.943	EPSD;PhosphoSitePlus	COSMIC	5.471	Down-regulation
TK_FGFR_FGFR1_Y	P11362	FGFR1	P11362	FGFR1	Y585	E592K	592	Missense	distal	7	no	8.995	8.794	EPSD;PhosphoSitePlus	COSMIC	5.471	Down-regulation
TK_FGFR_FGFR1_Y	P11362	FGFR1	P11362	FGFR1	Y585	P587H	587	Missense	proximal	2	no	8.995	8.824	EPSD;PhosphoSitePlus	COSMIC	5.471	Down-regulation
TK_FGFR_FGFR1_Y	P11362	FGFR1	P11362	FGFR1	Y605	G610D	610	Missense	distal	5	no	11.441	11.370	EPSD	COSMIC	5.471	Down-regulation
TK_FGFR_FGFR1_Y	P11362	FGFR1	P11362	FGFR1	Y605	S602F	602	Missense	distal	-3	no	11.441	12.130	EPSD	COSMIC	5.471	Up-regulation
TK_FGFR_FGFR1_Y	P11362	FGFR1	P11362	FGFR1	Y605	A604T	604	Missense	proximal	-1	no	11.441	12.471	EPSD	COSMIC	5.471	Up-regulation
TK_FGFR_FGFR1_Y	P11362	FGFR1	P11362	FGFR1	Y605	E612G	612	Missense	distal	7	no	11.441	9.983	EPSD	COSMIC	5.471	Down-regulation
TK_FGFR_FGFR1_Y	P11362	FGFR1	P11362	FGFR1	Y605	R609Q	609	Missense	distal	4	no	11.441	11.906	EPSD	COSMIC	5.471	Up-regulation
TK_FGFR_FGFR1_Y	P11362	FGFR1	P11362	FGFR1	Y605	E612Q	612	Missense	distal	7	no	11.441	10.882	EPSD	COSMIC	5.471	Down-regulation
TK_FGFR_FGFR1_Y	P11362	FGFR1	P11362	FGFR1	Y605	A608D	608	Missense	distal	3	no	11.441	10.808	EPSD	COSMIC	5.471	Down-regulation
TK_FGFR_FGFR1_Y	P11362	FGFR1	P11362	FGFR1	Y605	D599N	599	Missense	distal	-6	no	11.441	11.433	EPSD	COSMIC	5.471	Down-regulation
TK_FGFR_FGFR1_Y	P11362	FGFR1	P11362	FGFR1	Y605	K598N	598	Missense	distal	-7	no	11.441	11.444	EPSD	COSMIC	5.471	Up-regulation
TK_FGFR_FGFR1_Y	P11362	FGFR1	P11362	FGFR1	Y653	K655R	655	Missense	proximal	2	no	7.741	7.847	EPSD;PhosphoSitePlus	COSMIC	5.471	Up-regulation
TK_FGFR_FGFR1_Y	P11362	FGFR1	P11362	FGFR1	Y653	K655E	655	Missense	proximal	2	no	7.741	7.846	EPSD;PhosphoSitePlus	COSMIC	5.471	Up-regulation
TK_FGFR_FGFR1_Y	P11362	FGFR1	P11362	FGFR1	Y653	K656E	656	Missense	distal	3	no	7.741	9.325	EPSD;PhosphoSitePlus	COSMIC	5.471	Up-regulation
TK_FGFR_FGFR1_Y	P11362	FGFR1	P11362	FGFR1	Y653	K656M	656	Missense	distal	3	no	7.741	9.312	EPSD;PhosphoSitePlus	COSMIC	5.471	Up-regulation
TK_FGFR_FGFR1_Y	P11362	FGFR1	P11362	FGFR1	Y653	K656N	656	Missense	distal	3	no	7.741	8.881	EPSD;PhosphoSitePlus	COSMIC	5.471	Up-regulation
TK_FGFR_FGFR1_Y	P11362	FGFR1	P11362	FGFR1	Y653	R646W	646	Missense	distal	-7	no	7.741	7.780	EPSD;PhosphoSitePlus	COSMIC	5.471	Up-regulation
TK_FGFR_FGFR1_Y	P11362	FGFR1	P11362	FGFR1	Y653	D647N	647	Missense	distal	-6	no	7.741	7.733	EPSD;PhosphoSitePlus	COSMIC	5.471	Down-regulation
TK_FGFR_FGFR1_Y	P11362	FGFR1	P11362	FGFR1	Y653	D652G	652	Missense	proximal	-1	no	7.741	7.066	EPSD;PhosphoSitePlus	COSMIC	5.471	Down-regulation
TK_FGFR_FGFR1_Y	P11362	FGFR1	P11362	FGFR1	Y653	G660S	660	Missense	distal	7	no	7.741	8.615	EPSD;PhosphoSitePlus	COSMIC	5.471	Up-regulation
TK_FGFR_FGFR1_Y	P11362	FGFR1	P11362	FGFR1	Y653	R646Q	646	Missense	distal	-7	no	7.741	7.740	EPSD;PhosphoSitePlus	COSMIC	5.471	Down-regulation
TK_FGFR_FGFR1_Y	P11362	FGFR1	P11362	FGFR1	Y653	I651T	651	Missense	proximal	-2	no	7.741	7.307	EPSD;PhosphoSitePlus	COSMIC	5.471	Down-regulation
TK_FGFR_FGFR1_Y	P11362	FGFR1	P11362	FGFR1	Y653	K655I	655	Missense	proximal	2	no	7.741	7.660	EPSD;PhosphoSitePlus	COSMIC	5.471	Down-regulation
TK_FGFR_FGFR1_Y	P11362	FGFR1	P11362	FGFR1	Y653	D652N	652	Missense	proximal	-1	no	7.741	8.095	EPSD;PhosphoSitePlus	COSMIC	5.471	Up-regulation
TK_FGFR_FGFR1_Y	P11362	FGFR1	P11362	FGFR1	Y653	H649Y	649	Missense	distal	-4	no	7.741	7.859	EPSD;PhosphoSitePlus	COSMIC	5.471	Up-regulation
TK_FGFR_FGFR1_Y	P11362	FGFR1	P11362	FGFR1	Y654	K655R	655	Missense	proximal	1	no	6.749	6.750	PhosphoSitePlus;EPSD	COSMIC	5.471	Up-regulation
TK_FGFR_FGFR1_Y	P11362	FGFR1	P11362	FGFR1	Y654	K655E	655	Missense	proximal	1	no	6.749	6.750	PhosphoSitePlus;EPSD	COSMIC	5.471	Up-regulation
TK_FGFR_FGFR1_Y	P11362	FGFR1	P11362	FGFR1	Y654	K656E	656	Missense	proximal	2	no	6.749	6.853	PhosphoSitePlus;EPSD	COSMIC	5.471	Up-regulation
TK_FGFR_FGFR1_Y	P11362	FGFR1	P11362	FGFR1	Y654	K656M	656	Missense	proximal	2	no	6.749	6.842	PhosphoSitePlus;EPSD	COSMIC	5.471	Up-regulation
TK_FGFR_FGFR1_Y	P11362	FGFR1	P11362	FGFR1	Y654	K656N	656	Missense	proximal	2	no	6.749	6.802	PhosphoSitePlus;EPSD	COSMIC	5.471	Up-regulation
TK_FGFR_FGFR1_Y	P11362	FGFR1	P11362	FGFR1	Y654	D647N	647	Missense	distal	-7	no	6.749	6.732	PhosphoSitePlus;EPSD	COSMIC	5.471	Down-regulation
TK_FGFR_FGFR1_Y	P11362	FGFR1	P11362	FGFR1	Y654	D652G	652	Missense	proximal	-2	no	6.749	6.637	PhosphoSitePlus;EPSD	COSMIC	5.471	Down-regulation
TK_FGFR_FGFR1_Y	P11362	FGFR1	P11362	FGFR1	Y654	G660S	660	Missense	distal	6	no	6.749	6.754	PhosphoSitePlus;EPSD	COSMIC	5.471	Up-regulation
TK_FGFR_FGFR1_Y	P11362	FGFR1	P11362	FGFR1	Y654	I651T	651	Missense	distal	-3	no	6.749	4.842	PhosphoSitePlus;EPSD	COSMIC	5.471	Loss
TK_FGFR_FGFR1_Y	P11362	FGFR1	P11362	FGFR1	Y654	R661Q	661	Missense	distal	7	no	6.749	6.822	PhosphoSitePlus;EPSD	COSMIC	5.471	Up-regulation
TK_FGFR_FGFR1_Y	P11362	FGFR1	P11362	FGFR1	Y654	K655I	655	Missense	proximal	1	no	6.749	6.748	PhosphoSitePlus;EPSD	COSMIC	5.471	Down-regulation
TK_FGFR_FGFR1_Y	P11362	FGFR1	P11362	FGFR1	Y654	D652N	652	Missense	proximal	-2	no	6.749	6.725	PhosphoSitePlus;EPSD	COSMIC	5.471	Down-regulation
TK_FGFR_FGFR1_Y	P11362	FGFR1	P11362	FGFR1	Y654	H649Y	649	Missense	distal	-5	no	6.749	5.524	PhosphoSitePlus;EPSD	COSMIC	5.471	Down-regulation
TK_FGFR_FGFR1_Y	P11362	FGFR1	P11362	FGFR1	Y677	T678S	678	Missense	proximal	1	no	7.247	7.245	EPSD	COSMIC	5.471	Down-regulation
TK_FGFR_FGFR1_Y	P11362	FGFR1	P11362	FGFR1	Y677	W684G	684	Missense	distal	7	no	7.247	7.054	EPSD	COSMIC	5.471	Down-regulation
TK_FGFR_FGFR1_Y	P11362	FGFR1	P11362	FGFR1	Y677	R675Q	675	Missense	proximal	-2	no	7.247	7.154	EPSD	COSMIC	5.471	Down-regulation
TK_FGFR_FGFR1_Y	P11362	FGFR1	P11362	FGFR1	Y677	E670G	670	Missense	distal	-7	no	7.247	7.265	EPSD	COSMIC	5.471	Up-regulation
TK_FGFR_FGFR1_Y	P11362	FGFR1	P11362	FGFR1	Y701	P700T	700	Missense	proximal	-1	no	7.463	8.410	EPSD	COSMIC	5.471	Up-regulation
TK_FGFR_FGFR1_Y	P11362	FGFR1	P11362	FGFR1	Y701	G703S	703	Missense	proximal	2	no	7.463	7.582	EPSD	COSMIC	5.471	Up-regulation
TK_FGFR_FGFR1_Y	P11362	FGFR1	P11362	FGFR1	Y701	E707Q	707	Missense	distal	6	no	7.463	7.467	EPSD	COSMIC	5.471	Up-regulation
TK_FGFR_FGFR1_Y	P11362	FGFR1	P11362	FGFR1	Y701	E708K	708	Missense	distal	7	no	7.463	7.262	EPSD	COSMIC	5.471	Down-regulation
TK_FGFR_FGFR1_Y	P11362	FGFR1	P11362	FGFR1	Y701	V706A	706	Missense	distal	5	no	7.463	7.531	EPSD	COSMIC	5.471	Up-regulation
TK_FGFR_FGFR1_Y	P11362	FGFR1	P11362	FGFR1	Y701	E708D	708	Missense	distal	7	no	7.463	6.519	EPSD	COSMIC	5.471	Down-regulation
TK_FGFR_FGFR1_Y	P11362	FGFR1	P11362	FGFR1	Y701	G698S	698	Missense	distal	-3	no	7.463	6.703	EPSD	COSMIC	5.471	Down-regulation
TK_FGFR_FGFR1_Y	P11362	FGFR1	P11362	FGFR1	Y701	V704I	704	Missense	distal	3	no	7.463	7.904	EPSD	COSMIC	5.471	Up-regulation
TK_FGFR_FGFR1_Y	P11362	FGFR1	P11362	FGFR1	Y701	S699P	699	Missense	proximal	-2	no	7.463	7.451	EPSD	COSMIC	5.471	Down-regulation
TK_FGFR_FGFR1_Y	P11362	FGFR1	P11362	FGFR1	Y701	V706I	706	Missense	distal	5	no	7.463	6.952	EPSD	COSMIC	5.471	Down-regulation
TK_FGFR_FGFR1_Y	P11362	FGFR1	P11362	FGFR1	Y730	R734L	734	Missense	distal	4	no	7.496	7.569	EPSD;PhosphoSitePlus	COSMIC	5.471	Up-regulation
TK_FGFR_FGFR1_Y	P11362	FGFR1	P11362	FGFR1	Y730	E728K	728	Missense	proximal	-2	no	7.496	7.467	EPSD;PhosphoSitePlus	COSMIC	5.471	Down-regulation
TK_FGFR_FGFR1_Y	P11362	FGFR1	P11362	FGFR1	Y730	R734Q	734	Missense	distal	4	no	7.496	7.961	EPSD;PhosphoSitePlus	COSMIC	5.471	Up-regulation
TK_FGFR_FGFR1_Y	P11362	FGFR1	P11362	FGFR1	Y730	R734W	734	Missense	distal	4	no	7.496	6.914	EPSD;PhosphoSitePlus	COSMIC	5.471	Down-regulation
TK_FGFR_FGFR1_Y	P11362	FGFR1	P11362	FGFR1	Y730	D735N	735	Missense	distal	5	no	7.496	7.843	EPSD;PhosphoSitePlus	COSMIC;GDSC;CCLE	5.471	Up-regulation
TK_FGFR_FGFR1_Y	P11362	FGFR1	P11362	FGFR1	Y730	E728D	728	Missense	proximal	-2	no	7.496	7.594	EPSD;PhosphoSitePlus	COSMIC	5.471	Up-regulation
TK_FGFR_FGFR1_Y	P11362	FGFR1	P11362	FGFR1	Y730	D735H	735	Missense	distal	5	no	7.496	7.137	EPSD;PhosphoSitePlus	COSMIC	5.471	Down-regulation
TK_FGFR_FGFR1_Y	P11362	FGFR1	P11362	FGFR1	Y766	L760V	760	Missense	distal	-6	no	7.865	7.868	EPSD;PhosphoSitePlus	COSMIC	5.471	Up-regulation
TK_FGFR_FGFR1_Y	P11362	FGFR1	P11362	FGFR1	Y766	P772S	772	Missense	distal	6	no	7.865	7.869	EPSD;PhosphoSitePlus	COSMIC;GDSC	5.471	Up-regulation
TK_FGFR_FGFR1_Y	P11362	FGFR1	P11362	FGFR1	Y766	P772H	772	Missense	distal	6	no	7.865	7.864	EPSD;PhosphoSitePlus	COSMIC	5.471	Down-regulation
TK_FGFR_FGFR1_Y	P11362	FGFR1	P11362	FGFR1	Y776	S779C	779	Missense	distal	3	no	7.620	4.846	EPSD	COSMIC	5.471	Loss
TK_FGFR_FGFR1_Y	P11362	FGFR1	P11362	FGFR1	Y776	P772S	772	Missense	distal	-4	no	7.620	6.933	EPSD	COSMIC;GDSC	5.471	Down-regulation
TK_FGFR_FGFR1_Y	P11362	FGFR1	P11362	FGFR1	Y776	D782N	782	Missense	distal	6	no	7.620	7.624	EPSD	COSMIC	5.471	Up-regulation
TK_FGFR_FGFR1_Y	P11362	FGFR1	P11362	FGFR1	Y776	P772H	772	Missense	distal	-4	no	7.620	7.793	EPSD	COSMIC	5.471	Up-regulation
TK_FGFR_FGFR1_Y	P16144	ITGB4	P11362	FGFR1	Y1564	Y1564H	1564	Missense	central	0	yes	8.682	0.000	PhosphoSitePlus	COSMIC;GDSC	5.471	Loss
TK_FGFR_FGFR1_Y	P16144	ITGB4	P11362	FGFR1	Y1564	E1571G	1571	Missense	distal	7	no	8.682	7.223	PhosphoSitePlus	COSMIC	5.471	Down-regulation
TK_FGFR_FGFR1_Y	P16144	ITGB4	P11362	FGFR1	Y1564	G1569S	1569	Missense	distal	5	no	8.682	9.351	PhosphoSitePlus	COSMIC	5.471	Up-regulation
TK_FGFR_FGFR1_Y	Q9UBW7	ZMYM2	P11362	FGFR1	Y502	C495F	495	Missense	distal	-7	no	7.710	7.721	EPSD;PhosphoSitePlus	COSMIC	5.471	Up-regulation
TK_FGFR_FGFR1_Y	Q9UBW7	ZMYM2	P11362	FGFR1	Y502	V505L	505	Missense	distal	3	no	7.710	7.877	EPSD;PhosphoSitePlus	COSMIC	5.471	Up-regulation
TK_FGFR_FGFR1_Y	Q9UBW7	ZMYM2	P11362	FGFR1	Y557	M558V	558	Missense	proximal	1	no	7.516	7.517	EPSD;PhosphoSitePlus	COSMIC;CCLE	5.471	Up-regulation
TK_FGFR_FGFR1_Y	Q9UBW7	ZMYM2	P11362	FGFR1	Y595	G602V	602	Missense	distal	7	no	7.727	8.101	PhosphoSitePlus;EPSD	COSMIC	5.471	Up-regulation
TK_FGFR_FGFR1_Y	Q9UBW7	ZMYM2	P11362	FGFR1	Y605	G602V	602	Missense	distal	-3	no	10.063	9.199	EPSD;PhosphoSitePlus	COSMIC	5.471	Down-regulation
TK_FGFR_FGFR1_Y	Q9UBW7	ZMYM2	P11362	FGFR1	Y680	Y683C	683	Missense	distal	3	no	8.296	8.223	EPSD;PhosphoSitePlus	COSMIC	5.471	Down-regulation
TK_FGFR_FGFR1_Y	Q9UBW7	ZMYM2	P11362	FGFR1	Y680	E686Q	686	Missense	distal	6	no	8.296	8.300	EPSD;PhosphoSitePlus	COSMIC	5.471	Up-regulation
TK_FGFR_FGFR1_Y	Q9UBW7	ZMYM2	P11362	FGFR1	Y683	Y683C	683	Missense	central	0	yes	8.602	0.000	EPSD;PhosphoSitePlus	COSMIC	5.471	Loss
TK_FGFR_FGFR1_Y	Q9UBW7	ZMYM2	P11362	FGFR1	Y683	E686Q	686	Missense	distal	3	no	8.602	7.917	EPSD;PhosphoSitePlus	COSMIC	5.471	Down-regulation
TK_FGFR_FGFR1_Y	Q9UBW7	ZMYM2	P11362	FGFR1	Y729	Q732H	732	Missense	distal	3	no	8.607	6.895	EPSD;PhosphoSitePlus	COSMIC	5.471	Down-regulation
TK_FGFR_FGFR1_Y	Q9UBW7	ZMYM2	P11362	FGFR1	Y862	M857I	857	Missense	distal	-5	no	5.212	6.416	EPSD	COSMIC	5.471	Gain
TK_FGFR_FGFR1_Y	Q9Y2J4	AMOTL2	P11362	FGFR1	Y107	P105A	105	Missense	proximal	-2	no	7.154	7.134	PhosphoSitePlus	COSMIC	5.471	Down-regulation
TK_FGFR_FGFR1_Y	Q9P0J1	PDP1	P11362	FGFR1	Y381	N377S	377	Missense	distal	-4	no	7.437	6.775	PhosphoSitePlus	COSMIC;GDSC;CCLE	5.471	Down-regulation
TK_FGFR_FGFR1_Y	Q15118	PDK1	P11362	FGFR1	Y136	A134T	134	Missense	proximal	-2	no	7.571	7.458	PhosphoSitePlus;EPSD	COSMIC	5.471	Down-regulation
TK_FGFR_FGFR1_Y	Q15118	PDK1	P11362	FGFR1	Y243	R238H	238	Missense	distal	-5	no	8.210	9.933	EPSD;PhosphoSitePlus	COSMIC	5.471	Up-regulation
TK_FGFR_FGFR1_Y	Q15118	PDK1	P11362	FGFR1	Y243	A236D	236	Missense	distal	-7	no	8.210	8.240	EPSD;PhosphoSitePlus	COSMIC	5.471	Up-regulation
TK_FGFR_FGFR1_Y	Q15118	PDK1	P11362	FGFR1	Y244	R238H	238	Missense	distal	-6	no	8.792	8.736	EPSD;PhosphoSitePlus	COSMIC	5.471	Down-regulation
TK_FGFR_FGFR1_Y	P00338	LDHA	P11362	FGFR1	Y10	T3I	3	Missense	distal	-7	no	5.782	5.838	PhosphoSitePlus;EPSD	COSMIC	5.471	Up-regulation
TK_FGFR_FGFR1_Y	P00338	LDHA	P11362	FGFR1	Y83	T86A	86	Missense	distal	3	no	7.657	7.200	EPSD;PhosphoSitePlus	COSMIC	5.471	Down-regulation
AGC_GRK_BARK_GRK3_ST	P07550	ADRB2	P35626	GRK3	S355	S355F	355	Missense	central	0	yes	22.034	0.000	PhosphoSitePlus;EPSD	COSMIC	9.327	Loss
AGC_GRK_BARK_GRK3_ST	P07550	ADRB2	P35626	GRK3	S356	S355F	355	Missense	proximal	-1	no	20.543	18.313	EPSD;PhosphoSitePlus	COSMIC	9.327	Down-regulation
AGC_GRK_BARK_GRK3_ST	P07550	ADRB2	P35626	GRK3	S364	E369V	369	Missense	distal	5	no	17.055	15.281	EPSD	COSMIC	9.327	Down-regulation
AGC_GRK_BARK_GRK3_ST	P41146	OPRL1	P35626	GRK3	S164	R162C	162	Missense	proximal	-2	no	12.344	10.142	EPSD	COSMIC	9.327	Down-regulation
AGC_GRK_BARK_GRK3_ST	P41146	OPRL1	P35626	GRK3	S164	R157H	157	Missense	distal	-7	no	12.344	9.902	EPSD	COSMIC	9.327	Down-regulation
AGC_GRK_BARK_GRK3_ST	P41146	OPRL1	P35626	GRK3	S164	R157S	157	Missense	distal	-7	no	12.344	12.197	EPSD	COSMIC	9.327	Down-regulation
AGC_GRK_BARK_GRK3_ST	P41146	OPRL1	P35626	GRK3	S164	Q168H	168	Missense	distal	4	no	12.344	11.844	EPSD	COSMIC	9.327	Down-regulation
AGC_GRK_BARK_GRK3_ST	P41146	OPRL1	P35626	GRK3	S164	V161F	161	Missense	distal	-3	no	12.344	12.050	EPSD	COSMIC	9.327	Down-regulation
AGC_GRK_BARK_GRK3_ST	P41146	OPRL1	P35626	GRK3	S164	T163M	163	Missense	proximal	-1	no	12.344	12.664	EPSD	COSMIC	9.327	Up-regulation
AGC_GRK_BARK_GRK3_ST	P41146	OPRL1	P35626	GRK3	S165	R162C	162	Missense	distal	-3	no	11.421	10.653	EPSD	COSMIC	9.327	Down-regulation
AGC_GRK_BARK_GRK3_ST	P41146	OPRL1	P35626	GRK3	S165	Q168H	168	Missense	distal	3	no	11.421	10.708	EPSD	COSMIC	9.327	Down-regulation
AGC_GRK_BARK_GRK3_ST	P41146	OPRL1	P35626	GRK3	S165	V161F	161	Missense	distal	-4	no	11.421	11.096	EPSD	COSMIC	9.327	Down-regulation
AGC_GRK_BARK_GRK3_ST	P41146	OPRL1	P35626	GRK3	S165	T163M	163	Missense	proximal	-2	no	11.421	11.607	EPSD	COSMIC	9.327	Up-regulation
AGC_SGK_SGK3_ST	Q96J02	ITCH	Q96BR1	SGK3	T214	S210F	210	Missense	distal	-4	no	2.257	2.231	EPSD	COSMIC	2.112	Down-regulation
AGC_SGK_SGK3_ST	Q96J02	ITCH	Q96BR1	SGK3	T214	N219K	219	Missense	distal	5	no	2.257	2.197	EPSD	COSMIC	2.112	Down-regulation
AGC_SGK_SGK3_ST	Q96J02	ITCH	Q96BR1	SGK3	T214	R215Q	215	Missense	proximal	1	no	2.257	2.221	EPSD	COSMIC	2.112	Down-regulation
AGC_SGK_SGK3_ST	Q96J02	ITCH	Q96BR1	SGK3	T214	R215G	215	Missense	proximal	1	no	2.257	2.250	EPSD	COSMIC	2.112	Down-regulation
AGC_SGK_SGK3_ST	Q96J02	ITCH	Q96BR1	SGK3	T218	N219K	219	Missense	proximal	1	no	4.879	4.906	EPSD	COSMIC	2.112	Up-regulation
AGC_SGK_SGK3_ST	Q96J02	ITCH	Q96BR1	SGK3	T218	R215Q	215	Missense	distal	-3	no	4.879	0.535	EPSD	COSMIC	2.112	Loss
AGC_SGK_SGK3_ST	Q96J02	ITCH	Q96BR1	SGK3	T218	R215G	215	Missense	distal	-3	no	4.879	0.258	EPSD	COSMIC	2.112	Loss
AGC_SGK_SGK3_ST	Q96J02	ITCH	Q96BR1	SGK3	T218	D222N	222	Missense	distal	4	no	4.879	4.846	EPSD	COSMIC	2.112	Down-regulation
AGC_SGK_SGK3_ST	Q96J02	ITCH	Q96BR1	SGK3	S236	S242P	242	Missense	distal	6	no	4.554	4.636	EPSD	COSMIC	2.112	Up-regulation
AGC_SGK_SGK3_ST	Q96J02	ITCH	Q96BR1	SGK3	S236	S242F	242	Missense	distal	6	no	4.554	4.708	EPSD	COSMIC	2.112	Up-regulation
AGC_SGK_SGK3_ST	Q96J02	ITCH	Q96BR1	SGK3	T263	P267L	267	Missense	distal	4	no	2.814	2.787	EPSD	COSMIC	2.112	Down-regulation
AGC_SGK_SGK3_ST	Q96J02	ITCH	Q96BR1	SGK3	T263	S257Y	257	Missense	distal	-6	no	2.814	2.834	EPSD	COSMIC	2.112	Up-regulation
AGC_SGK_SGK3_ST	Q96J02	ITCH	Q96BR1	SGK3	T263	P262S	262	Missense	proximal	-1	no	2.814	3.114	EPSD	COSMIC	2.112	Up-regulation
AGC_SGK_SGK3_ST	Q96J02	ITCH	Q96BR1	SGK3	T263	R265H	265	Missense	proximal	2	no	2.814	2.964	EPSD	COSMIC	2.112	Up-regulation
AGC_SGK_SGK3_ST	Q96J02	ITCH	Q96BR1	SGK3	T263	S269C	269	Missense	distal	6	no	2.814	2.890	EPSD	COSMIC	2.112	Up-regulation
AGC_SGK_SGK3_ST	Q96J02	ITCH	Q96BR1	SGK3	T385	W386L	386	Missense	proximal	1	no	8.899	8.863	EPSD;PhosphoSitePlus	COSMIC	2.112	Down-regulation
AGC_SGK_SGK3_ST	Q96J02	ITCH	Q96BR1	SGK3	T385	H379R	379	Missense	distal	-6	no	8.899	8.936	EPSD;PhosphoSitePlus	COSMIC;CCLE	2.112	Up-regulation
AGC_SGK_SGK3_ST	Q96J02	ITCH	Q96BR1	SGK3	T385	H379D	379	Missense	distal	-6	no	8.899	8.906	EPSD;PhosphoSitePlus	COSMIC	2.112	Up-regulation
AGC_SGK_SGK3_ST	Q96J02	ITCH	Q96BR1	SGK3	T504	R501I	501	Missense	distal	-3	no	4.318	0.089	EPSD	COSMIC	2.112	Loss
AGC_SGK_SGK3_ST	Q96J02	ITCH	Q96BR1	SGK3	T505	R501I	501	Missense	distal	-4	no	6.089	5.826	EPSD	COSMIC	2.112	Down-regulation
AGC_SGK_SGK3_ST	Q13045	FLII	Q96BR1	SGK3	S62	S64N	64	Missense	proximal	2	no	2.302	2.001	EPSD	COSMIC	2.112	Loss
AGC_SGK_SGK3_ST	Q13045	FLII	Q96BR1	SGK3	S90	P97S	97	Missense	distal	7	no	3.839	3.843	EPSD	COSMIC	2.112	Up-regulation
AGC_SGK_SGK3_ST	Q13045	FLII	Q96BR1	SGK3	S90	K92R	92	Missense	proximal	2	no	3.839	3.520	EPSD	COSMIC	2.112	Down-regulation
AGC_SGK_SGK3_ST	Q13045	FLII	Q96BR1	SGK3	S90	V85M	85	Missense	distal	-5	no	3.839	3.876	EPSD	COSMIC	2.112	Up-regulation
AGC_SGK_SGK3_ST	Q13045	FLII	Q96BR1	SGK3	S406	A403P	403	Missense	distal	-3	no	2.410	2.094	EPSD	COSMIC	2.112	Loss
AGC_SGK_SGK3_ST	Q13045	FLII	Q96BR1	SGK3	S406	A403G	403	Missense	distal	-3	no	2.410	2.071	EPSD	COSMIC	2.112	Loss
AGC_SGK_SGK3_ST	Q13045	FLII	Q96BR1	SGK3	S406	A411T	411	Missense	distal	5	no	2.410	2.455	EPSD	COSMIC	2.112	Up-regulation
AGC_SGK_SGK3_ST	Q13045	FLII	Q96BR1	SGK3	S406	A412T	412	Missense	distal	6	no	2.410	2.329	EPSD	COSMIC	2.112	Down-regulation
AGC_SGK_SGK3_ST	Q13045	FLII	Q96BR1	SGK3	S436	R433C	433	Missense	distal	-3	no	8.948	4.683	PhosphoSitePlus;EPSD	COSMIC	2.112	Down-regulation
AGC_SGK_SGK3_ST	Q13045	FLII	Q96BR1	SGK3	S436	R429L	429	Missense	distal	-7	no	8.948	9.350	PhosphoSitePlus;EPSD	COSMIC	2.112	Up-regulation
AGC_SGK_SGK3_ST	Q13045	FLII	Q96BR1	SGK3	S436	D440E	440	Missense	distal	4	no	8.948	8.905	PhosphoSitePlus;EPSD	COSMIC	2.112	Down-regulation
AGC_SGK_SGK3_ST	Q13045	FLII	Q96BR1	SGK3	S436	R432C	432	Missense	distal	-4	no	8.948	8.684	PhosphoSitePlus;EPSD	COSMIC	2.112	Down-regulation
AGC_SGK_SGK3_ST	Q13045	FLII	Q96BR1	SGK3	S436	D439E	439	Missense	distal	3	no	8.948	9.064	PhosphoSitePlus;EPSD	COSMIC	2.112	Up-regulation
AGC_SGK_SGK3_ST	Q13045	FLII	Q96BR1	SGK3	T665	K671T	671	Missense	distal	6	no	2.275	2.189	EPSD	COSMIC	2.112	Down-regulation
AGC_SGK_SGK3_ST	Q13045	FLII	Q96BR1	SGK3	T665	R660L	660	Missense	distal	-5	no	2.275	0.390	EPSD	COSMIC	2.112	Loss
AGC_SGK_SGK3_ST	Q13045	FLII	Q96BR1	SGK3	T665	A662G	662	Missense	distal	-3	no	2.275	1.936	EPSD	COSMIC	2.112	Loss
AGC_SGK_SGK3_ST	Q13045	FLII	Q96BR1	SGK3	T665	Q663P	663	Missense	proximal	-2	no	2.275	2.264	EPSD	COSMIC	2.112	Down-regulation
AGC_SGK_SGK3_ST	Q13045	FLII	Q96BR1	SGK3	T665	A672T	672	Missense	distal	7	no	2.275	2.286	EPSD	COSMIC	2.112	Up-regulation
AGC_SGK_SGK3_ST	Q13045	FLII	Q96BR1	SGK3	T670	R673W	673	Missense	distal	3	no	2.475	0.795	EPSD	COSMIC	2.112	Loss
AGC_SGK_SGK3_ST	Q13045	FLII	Q96BR1	SGK3	T670	K671T	671	Missense	proximal	1	no	2.475	2.436	EPSD	COSMIC	2.112	Down-regulation
AGC_SGK_SGK3_ST	Q13045	FLII	Q96BR1	SGK3	T670	E677D	677	Missense	distal	7	no	2.475	2.478	EPSD	COSMIC	2.112	Up-regulation
AGC_SGK_SGK3_ST	Q13045	FLII	Q96BR1	SGK3	T670	Q663P	663	Missense	distal	-7	no	2.475	2.651	EPSD	COSMIC	2.112	Up-regulation
AGC_SGK_SGK3_ST	Q13045	FLII	Q96BR1	SGK3	T670	R673S	673	Missense	distal	3	no	2.475	0.697	EPSD	COSMIC	2.112	Loss
AGC_SGK_SGK3_ST	Q13045	FLII	Q96BR1	SGK3	T670	A672T	672	Missense	proximal	2	no	2.475	2.257	EPSD	COSMIC	2.112	Down-regulation
AGC_SGK_SGK3_ST	Q13045	FLII	Q96BR1	SGK3	T818	R813W	813	Missense	distal	-5	no	9.197	7.542	EPSD;PhosphoSitePlus	COSMIC	2.112	Down-regulation
AGC_SGK_SGK3_ST	Q13045	FLII	Q96BR1	SGK3	T818	R815H	815	Missense	distal	-3	no	9.197	4.895	EPSD;PhosphoSitePlus	COSMIC	2.112	Down-regulation
AGC_SGK_SGK3_ST	Q13045	FLII	Q96BR1	SGK3	T818	R815C	815	Missense	distal	-3	no	9.197	4.933	EPSD;PhosphoSitePlus	COSMIC;CCLE	2.112	Down-regulation
AGC_SGK_SGK3_ST	P49841	GSK3B	Q96BR1	SGK3	T7	S9F	9	Missense	proximal	2	no	4.624	4.121	EPSD	COSMIC	2.112	Down-regulation
AGC_SGK_SGK3_ST	P49841	GSK3B	Q96BR1	SGK3	T7	S2P	2	Missense	distal	-5	no	4.624	4.528	EPSD	COSMIC	2.112	Down-regulation
AGC_SGK_SGK3_ST	P49841	GSK3B	Q96BR1	SGK3	S9	S9F	9	Missense	central	0	yes	8.615	0.000	PhosphoSitePlus	COSMIC	2.112	Loss
AGC_SGK_SGK3_ST	P49841	GSK3B	Q96BR1	SGK3	S9	P16A	16	Missense	distal	7	no	8.615	8.612	PhosphoSitePlus	COSMIC	2.112	Down-regulation
AGC_SGK_SGK3_ST	P49841	GSK3B	Q96BR1	SGK3	S9	S2P	2	Missense	distal	-7	no	8.615	8.709	PhosphoSitePlus	COSMIC	2.112	Up-regulation
AGC_SGK_SGK3_ST	P49841	GSK3B	Q96BR1	SGK3	S35	D31Y	31	Missense	distal	-4	no	2.319	2.242	EPSD	COSMIC	2.112	Down-regulation
AGC_SGK_SGK3_ST	P49841	GSK3B	Q96BR1	SGK3	S35	D33N	33	Missense	proximal	-2	no	2.319	2.012	EPSD	COSMIC	2.112	Loss
AGC_SGK_SGK3_ST	P49841	GSK3B	Q96BR1	SGK3	S35	S35R	35	Missense	central	0	yes	2.319	0.000	EPSD	COSMIC	2.112	Loss
AGC_SGK_SGK3_ST	P49841	GSK3B	Q96BR1	SGK3	S35	V41G	41	Missense	distal	6	no	2.319	2.347	EPSD	COSMIC	2.112	Up-regulation
AGC_SGK_SGK3_ST	P49841	GSK3B	Q96BR1	SGK3	S35	V37G	37	Missense	proximal	2	no	2.319	2.608	EPSD	COSMIC	2.112	Up-regulation
AGC_SGK_SGK3_ST	P49841	GSK3B	Q96BR1	SGK3	S35	D33G	33	Missense	proximal	-2	no	2.319	1.944	EPSD	COSMIC;GDSC;CCLE	2.112	Loss
AGC_SGK_SGK3_ST	P49841	GSK3B	Q96BR1	SGK3	S35	D33H	33	Missense	proximal	-2	no	2.319	2.154	EPSD	COSMIC	2.112	Down-regulation
AGC_SGK_SGK3_ST	P49841	GSK3B	Q96BR1	SGK3	S147	P154S	154	Missense	distal	7	no	4.301	4.304	EPSD	COSMIC	2.112	Up-regulation
AGC_SGK_SGK3_ST	P49841	GSK3B	Q96BR1	SGK3	S147	Y146C	146	Missense	proximal	-1	no	4.301	4.395	EPSD	COSMIC	2.112	Up-regulation
AGC_SGK_SGK3_ST	P49841	GSK3B	Q96BR1	SGK3	S147	R148Q	148	Missense	proximal	1	no	4.301	4.265	EPSD	COSMIC	2.112	Down-regulation
AGC_SGK_SGK3_ST	P49841	GSK3B	Q96BR1	SGK3	S147	S147N	147	Missense	central	0	yes	4.301	0.000	EPSD	COSMIC	2.112	Loss
AGC_SGK_SGK3_ST	P49841	GSK3B	Q96BR1	SGK3	S147	Y140C	140	Missense	distal	-7	no	4.301	4.253	EPSD	COSMIC	2.112	Down-regulation
AGC_SGK_SGK3_ST	P49841	GSK3B	Q96BR1	SGK3	S147	A143G	143	Missense	distal	-4	no	4.301	4.272	EPSD	COSMIC	2.112	Down-regulation
AGC_SGK_SGK3_ST	P49841	GSK3B	Q96BR1	SGK3	S147	R141S	141	Missense	distal	-6	no	4.301	4.247	EPSD	COSMIC	2.112	Down-regulation
AGC_SGK_SGK3_ST	P49841	GSK3B	Q96BR1	SGK3	T402	R405S	405	Missense	distal	3	no	2.478	0.700	EPSD	COSMIC	2.112	Loss
AGC_SGK_SGK3_ST	P49841	GSK3B	Q96BR1	SGK3	T402	A397V	397	Missense	distal	-5	no	2.478	2.486	EPSD	COSMIC;CCLE	2.112	Up-regulation
AGC_SGK_SGK3_ST	P49841	GSK3B	Q96BR1	SGK3	T402	T402I	402	Missense	central	0	yes	2.478	0.000	EPSD	COSMIC	2.112	Loss
AGC_SGK_SGK3_ST	P49841	GSK3B	Q96BR1	SGK3	T402	R405H	405	Missense	distal	3	no	2.478	0.740	EPSD	COSMIC;CCLE	2.112	Loss
AGC_SGK_SGK3_ST	P49841	GSK3B	Q96BR1	SGK3	T408	R405S	405	Missense	distal	-3	no	4.316	-0.013	EPSD	COSMIC	2.112	Loss
AGC_SGK_SGK3_ST	P49841	GSK3B	Q96BR1	SGK3	T408	T402I	402	Missense	distal	-6	no	4.316	4.321	EPSD	COSMIC	2.112	Up-regulation
AGC_SGK_SGK3_ST	P49841	GSK3B	Q96BR1	SGK3	T408	R405H	405	Missense	distal	-3	no	4.316	0.013	EPSD	COSMIC;CCLE	2.112	Loss
Atypical_PIKK_ATM_ATM_ST	P25205	MCM3	Q13315	ATM	S112	V111I	111	Missense	proximal	-1	no	9.512	9.714	EPSD	COSMIC	9.540	Gain
Atypical_PIKK_ATM_ATM_ST	P25205	MCM3	Q13315	ATM	S112	R114Q	114	Missense	proximal	2	no	9.512	10.207	EPSD	COSMIC	9.540	Gain
Atypical_PIKK_ATM_ATM_ST	P25205	MCM3	Q13315	ATM	S160	T163I	163	Missense	distal	3	no	9.879	10.300	EPSD	COSMIC	9.540	Up-regulation
Atypical_PIKK_ATM_ATM_ST	P25205	MCM3	Q13315	ATM	S292	S292F	292	Missense	central	0	yes	10.324	0.000	EPSD	COSMIC	9.540	Loss
Atypical_PIKK_ATM_ATM_ST	P25205	MCM3	Q13315	ATM	S292	T290N	290	Missense	proximal	-2	no	10.324	10.232	EPSD	COSMIC	9.540	Down-regulation
Atypical_PIKK_ATM_ATM_ST	P25205	MCM3	Q13315	ATM	S292	L299P	299	Missense	distal	7	no	10.324	10.323	EPSD	COSMIC	9.540	Down-regulation
Atypical_PIKK_ATM_ATM_ST	P25205	MCM3	Q13315	ATM	S292	T290S	290	Missense	proximal	-2	no	10.324	10.412	EPSD	COSMIC	9.540	Up-regulation
Atypical_PIKK_ATM_ATM_ST	P25205	MCM3	Q13315	ATM	S477	R478Q	478	Missense	proximal	1	no	4.892	11.543	EPSD	COSMIC	9.540	Gain
Atypical_PIKK_ATM_ATM_ST	P25205	MCM3	Q13315	ATM	S535	D530H	530	Missense	distal	-5	no	14.733	14.992	PhosphoSitePlus	COSMIC	9.540	Up-regulation
Atypical_PIKK_ATM_ATM_ST	P25205	MCM3	Q13315	ATM	S535	Q536H	536	Missense	proximal	1	no	14.733	-0.176	PhosphoSitePlus	COSMIC	9.540	Loss
Atypical_PIKK_ATM_ATM_ST	P25205	MCM3	Q13315	ATM	S535	T529K	529	Missense	distal	-6	no	14.733	14.689	PhosphoSitePlus	COSMIC	9.540	Down-regulation
Atypical_PIKK_ATM_ATM_ST	P25205	MCM3	Q13315	ATM	T542	Y545S	545	Missense	distal	3	no	10.063	9.821	EPSD	COSMIC	9.540	Down-regulation
Atypical_PIKK_ATM_ATM_ST	P25205	MCM3	Q13315	ATM	T542	Q536H	536	Missense	distal	-6	no	10.063	9.920	EPSD	COSMIC	9.540	Down-regulation
Atypical_PIKK_ATM_ATM_ST	P25205	MCM3	Q13315	ATM	S599	R596H	596	Missense	distal	-3	no	14.961	14.315	EPSD	COSMIC	9.540	Down-regulation
Atypical_PIKK_ATM_ATM_ST	P25205	MCM3	Q13315	ATM	S599	M603L	603	Missense	distal	4	no	14.961	15.042	EPSD	COSMIC	9.540	Up-regulation
Atypical_PIKK_ATM_ATM_ST	P25205	MCM3	Q13315	ATM	S681	K688N	688	Missense	distal	7	no	17.752	17.744	EPSD	COSMIC	9.540	Down-regulation
Atypical_PIKK_ATM_ATM_ST	P25205	MCM3	Q13315	ATM	S681	D676N	676	Missense	distal	-5	no	17.752	17.935	EPSD	COSMIC	9.540	Up-regulation
Atypical_PIKK_ATM_ATM_ST	P25205	MCM3	Q13315	ATM	S681	Q685H	685	Missense	distal	4	no	17.752	17.836	EPSD	COSMIC	9.540	Up-regulation
Atypical_PIKK_ATM_ATM_ST	P25205	MCM3	Q13315	ATM	S681	E683K	683	Missense	proximal	2	no	17.752	16.421	EPSD	COSMIC	9.540	Down-regulation
Atypical_PIKK_ATM_ATM_ST	P25205	MCM3	Q13315	ATM	S704	D706N	706	Missense	proximal	2	no	10.159	9.138	EPSD	COSMIC	9.540	Loss
Atypical_PIKK_ATM_ATM_ST	P25205	MCM3	Q13315	ATM	S704	P707S	707	Missense	distal	3	no	10.159	10.008	EPSD	COSMIC	9.540	Down-regulation
Atypical_PIKK_ATM_ATM_ST	P25205	MCM3	Q13315	ATM	S704	D701N	701	Missense	distal	-3	no	10.159	9.887	EPSD	COSMIC	9.540	Down-regulation
Atypical_PIKK_ATM_ATM_ST	P25205	MCM3	Q13315	ATM	S704	S704L	704	Missense	central	0	yes	10.159	0.000	EPSD	COSMIC	9.540	Loss
Atypical_PIKK_ATM_ATM_ST	P25205	MCM3	Q13315	ATM	S704	D698N	698	Missense	distal	-6	no	10.159	10.071	EPSD	COSMIC	9.540	Down-regulation
Atypical_PIKK_ATM_ATM_ST	P25205	MCM3	Q13315	ATM	S728	E730K	730	Missense	proximal	2	no	16.571	15.241	EPSD	COSMIC	9.540	Down-regulation
Atypical_PIKK_ATM_ATM_ST	P25205	MCM3	Q13315	ATM	S728	A726T	726	Missense	proximal	-2	no	16.571	16.671	EPSD	COSMIC	9.540	Up-regulation
Atypical_PIKK_ATM_ATM_ST	P25205	MCM3	Q13315	ATM	S728	D727E	727	Missense	proximal	-1	no	16.571	16.836	EPSD	COSMIC	9.540	Up-regulation
Atypical_PIKK_ATM_ATM_ST	P25205	MCM3	Q13315	ATM	S734	E730K	730	Missense	distal	-4	no	13.918	12.946	EPSD	COSMIC	9.540	Down-regulation
Atypical_PIKK_ATM_ATM_ST	P25205	MCM3	Q13315	ATM	S734	D727E	727	Missense	distal	-7	no	13.918	14.496	EPSD	COSMIC	9.540	Up-regulation
Atypical_PIKK_ATM_ATM_ST	P25205	MCM3	Q13315	ATM	S734	E741D	741	Missense	distal	7	no	13.918	13.930	EPSD	COSMIC	9.540	Up-regulation
Atypical_PIKK_ATM_ATM_ST	P25205	MCM3	Q13315	ATM	S734	V737A	737	Missense	distal	3	no	13.918	13.630	EPSD	COSMIC	9.540	Down-regulation
Atypical_PIKK_ATM_ATM_ST	P25205	MCM3	Q13315	ATM	S740	R743M	743	Missense	distal	3	no	10.988	11.059	EPSD	COSMIC	9.540	Up-regulation
Atypical_PIKK_ATM_ATM_ST	P25205	MCM3	Q13315	ATM	S740	E741D	741	Missense	proximal	1	no	10.988	10.854	EPSD	COSMIC	9.540	Down-regulation
Atypical_PIKK_ATM_ATM_ST	P25205	MCM3	Q13315	ATM	S740	V737A	737	Missense	distal	-3	no	10.988	10.124	EPSD	COSMIC	9.540	Down-regulation
Atypical_PIKK_ATM_ATM_ST	P25205	MCM3	Q13315	ATM	S776	R774L	774	Missense	proximal	-2	no	10.570	10.624	EPSD	COSMIC	9.540	Up-regulation
Atypical_PIKK_ATM_ATM_ST	P25205	MCM3	Q13315	ATM	S776	R774W	774	Missense	proximal	-2	no	10.570	10.519	EPSD	COSMIC	9.540	Down-regulation
Atypical_PIKK_ATM_ATM_ST	P25205	MCM3	Q13315	ATM	S776	S781F	781	Missense	distal	5	no	10.570	10.877	EPSD	COSMIC	9.540	Up-regulation
Atypical_PIKK_ATM_ATM_ST	P25205	MCM3	Q13315	ATM	S776	E777K	777	Missense	proximal	1	no	10.570	9.619	EPSD	COSMIC	9.540	Down-regulation
Atypical_PIKK_ATM_ATM_ST	Q9NVI1	FANCI	Q13315	ATM	S407	E405D	405	Missense	proximal	-2	no	11.361	10.882	EPSD	COSMIC	9.540	Down-regulation
Atypical_PIKK_ATM_ATM_ST	Q9NVI1	FANCI	Q13315	ATM	S556	C558F	558	Missense	proximal	2	no	15.465	15.240	EPSD;PhosphoSitePlus	COSMIC	9.540	Down-regulation
Atypical_PIKK_ATM_ATM_ST	Q9NVI1	FANCI	Q13315	ATM	S559	C558F	558	Missense	proximal	-1	no	14.867	14.640	EPSD;PhosphoSitePlus	COSMIC	9.540	Down-regulation
Atypical_PIKK_ATM_ATM_ST	Q9NVI1	FANCI	Q13315	ATM	S565	C558F	558	Missense	distal	-7	no	13.688	13.532	EPSD	COSMIC	9.540	Down-regulation
Atypical_PIKK_ATM_ATM_ST	Q9NVI1	FANCI	Q13315	ATM	S565	H568R	568	Missense	distal	3	no	13.688	13.650	EPSD	COSMIC	9.540	Down-regulation
Atypical_PIKK_ATM_ATM_ST	Q9NVI1	FANCI	Q13315	ATM	S629	L627V	627	Missense	proximal	-2	no	14.137	13.862	EPSD	COSMIC	9.540	Down-regulation
Atypical_PIKK_ATM_ATM_ST	Q9NVI1	FANCI	Q13315	ATM	T653	L647F	647	Missense	distal	-6	no	10.521	10.278	EPSD	COSMIC	9.540	Down-regulation
Atypical_PIKK_ATM_ATM_ST	Q9NVI1	FANCI	Q13315	ATM	T653	C650S	650	Missense	distal	-3	no	10.521	10.353	EPSD	COSMIC	9.540	Down-regulation
Atypical_PIKK_ATM_ATM_ST	Q9NVI1	FANCI	Q13315	ATM	S726	S730F	730	Missense	distal	4	no	11.387	12.214	EPSD	COSMIC	9.540	Up-regulation
Atypical_PIKK_ATM_ATM_ST	Q9NVI1	FANCI	Q13315	ATM	S726	E722Q	722	Missense	distal	-4	no	11.387	10.663	EPSD	COSMIC	9.540	Down-regulation
Atypical_PIKK_ATM_ATM_ST	Q9NVI1	FANCI	Q13315	ATM	S730	S730F	730	Missense	central	0	yes	16.945	0.000	EPSD;PhosphoSitePlus	COSMIC	9.540	Loss
Atypical_PIKK_ATM_ATM_ST	Q9NVI1	FANCI	Q13315	ATM	S730	I735V	735	Missense	distal	5	no	16.945	16.948	EPSD;PhosphoSitePlus	COSMIC	9.540	Up-regulation
Atypical_PIKK_ATM_ATM_ST	Q9NVI1	FANCI	Q13315	ATM	T952	D948N	948	Missense	distal	-4	no	10.846	9.922	EPSD	COSMIC	9.540	Down-regulation
Atypical_PIKK_ATM_ATM_ST	Q9NVI1	FANCI	Q13315	ATM	S972	L966V	966	Missense	distal	-6	no	15.432	15.464	PhosphoSitePlus;EPSD	COSMIC	9.540	Up-regulation
Atypical_PIKK_ATM_ATM_ST	Q9NVI1	FANCI	Q13315	ATM	S972	L967V	967	Missense	distal	-5	no	15.432	15.523	PhosphoSitePlus;EPSD	COSMIC	9.540	Up-regulation
Atypical_PIKK_ATM_ATM_ST	Q9NVI1	FANCI	Q13315	ATM	S1050	D1048Y	1048	Missense	proximal	-2	no	14.190	14.319	EPSD	COSMIC;GDSC;CCLE	9.540	Up-regulation
Atypical_PIKK_ATM_ATM_ST	Q9NVI1	FANCI	Q13315	ATM	S1050	R1047H	1047	Missense	distal	-3	no	14.190	13.545	EPSD	COSMIC	9.540	Down-regulation
Atypical_PIKK_ATM_ATM_ST	Q9NVI1	FANCI	Q13315	ATM	S1121	Q1128H	1128	Missense	distal	7	no	15.858	15.877	EPSD;PhosphoSitePlus	COSMIC;CCLE	9.540	Up-regulation
Atypical_PIKK_ATM_ATM_ST	Q9NVI1	FANCI	Q13315	ATM	S1312	E1308K	1308	Missense	distal	-4	no	10.278	9.306	EPSD	COSMIC	9.540	Loss
Atypical_PIKK_ATM_ATM_ST	O60934	NBN	Q13315	ATM	S58	V65I	65	Missense	distal	7	no	16.155	16.137	EPSD	COSMIC	9.540	Down-regulation
Atypical_PIKK_ATM_ATM_ST	O60934	NBN	Q13315	ATM	S58	V65A	65	Missense	distal	7	no	16.155	16.137	EPSD	COSMIC	9.540	Down-regulation
Atypical_PIKK_ATM_ATM_ST	O60934	NBN	Q13315	ATM	S58	L57Q	57	Missense	proximal	-1	no	16.155	16.223	EPSD	COSMIC	9.540	Up-regulation
Atypical_PIKK_ATM_ATM_ST	O60934	NBN	Q13315	ATM	S278	D284H	284	Missense	distal	6	no	16.657	16.645	EPSD;PhosphoSitePlus	COSMIC	9.540	Down-regulation
Atypical_PIKK_ATM_ATM_ST	O60934	NBN	Q13315	ATM	S278	D272N	272	Missense	distal	-6	no	16.657	16.568	EPSD;PhosphoSitePlus	COSMIC	9.540	Down-regulation
Atypical_PIKK_ATM_ATM_ST	O60934	NBN	Q13315	ATM	S278	N277S	277	Missense	proximal	-1	no	16.657	16.712	EPSD;PhosphoSitePlus	COSMIC	9.540	Up-regulation
Atypical_PIKK_ATM_ATM_ST	O60934	NBN	Q13315	ATM	T337	L342H	342	Missense	distal	5	no	9.859	9.834	EPSD	COSMIC	9.540	Down-regulation
Atypical_PIKK_ATM_ATM_ST	O60934	NBN	Q13315	ATM	T337	P338S	338	Missense	proximal	1	no	9.859	2.884	EPSD	COSMIC	9.540	Loss
Atypical_PIKK_ATM_ATM_ST	O60934	NBN	Q13315	ATM	S343	L342H	342	Missense	proximal	-1	no	15.318	15.249	PhosphoSitePlus;EPSD	COSMIC	9.540	Down-regulation
Atypical_PIKK_ATM_ATM_ST	O60934	NBN	Q13315	ATM	S343	V346M	346	Missense	distal	3	no	15.318	15.230	PhosphoSitePlus;EPSD	COSMIC	9.540	Down-regulation
Atypical_PIKK_ATM_ATM_ST	O60934	NBN	Q13315	ATM	S343	P338S	338	Missense	distal	-5	no	15.318	15.314	PhosphoSitePlus;EPSD	COSMIC	9.540	Down-regulation
Atypical_PIKK_ATM_ATM_ST	O60934	NBN	Q13315	ATM	S397	R394I	394	Missense	distal	-3	no	13.676	13.606	EPSD;PhosphoSitePlus	COSMIC	9.540	Down-regulation
Atypical_PIKK_ATM_ATM_ST	O60934	NBN	Q13315	ATM	S397	R394G	394	Missense	distal	-3	no	13.676	13.214	EPSD;PhosphoSitePlus	COSMIC	9.540	Down-regulation
Atypical_PIKK_ATM_ATM_ST	O60934	NBN	Q13315	ATM	T493	P498L	498	Missense	distal	5	no	12.695	12.678	EPSD	COSMIC	9.540	Down-regulation
Atypical_PIKK_ATM_ATM_ST	O60934	NBN	Q13315	ATM	T493	S486F	486	Missense	distal	-7	no	12.695	11.865	EPSD	COSMIC	9.540	Down-regulation
Atypical_PIKK_ATM_ATM_ST	O60934	NBN	Q13315	ATM	S612	S615F	615	Missense	distal	3	no	9.079	9.661	EPSD	COSMIC	9.540	Gain
Atypical_PIKK_ATM_ATM_ST	O60934	NBN	Q13315	ATM	S615	S615F	615	Missense	central	0	yes	14.474	0.000	EPSD;PhosphoSitePlus	COSMIC	9.540	Loss
Atypical_PIKK_ATM_ATM_ST	O60934	NBN	Q13315	ATM	S615	Q616K	616	Missense	proximal	1	no	14.474	7.626	EPSD;PhosphoSitePlus	COSMIC	9.540	Loss
Atypical_PIKK_ATM_ATM_ST	O60934	NBN	Q13315	ATM	S615	V608I	608	Missense	distal	-7	no	14.474	14.290	EPSD;PhosphoSitePlus	COSMIC	9.540	Down-regulation
Atypical_PIKK_ATM_ATM_ST	O60934	NBN	Q13315	ATM	S673	Y679H	679	Missense	distal	6	no	9.535	9.542	EPSD	COSMIC	9.540	Gain
Atypical_PIKK_ATM_ATM_ST	O60934	NBN	Q13315	ATM	S738	L739P	739	Missense	proximal	1	no	8.955	10.510	EPSD	COSMIC	9.540	Gain
Atypical_PIKK_ATM_ATM_ST	P78527	PRKDC	Q13315	ATM	S141	R139T	139	Missense	proximal	-2	no	9.840	10.194	EPSD	COSMIC	9.540	Up-regulation
Atypical_PIKK_ATM_ATM_ST	P78527	PRKDC	Q13315	ATM	S503	R509H	509	Missense	distal	6	no	9.867	9.851	EPSD	COSMIC	9.540	Down-regulation
Atypical_PIKK_ATM_ATM_ST	P78527	PRKDC	Q13315	ATM	S503	G500C	500	Missense	distal	-3	no	9.867	9.756	EPSD	COSMIC	9.540	Down-regulation
Atypical_PIKK_ATM_ATM_ST	P78527	PRKDC	Q13315	ATM	S503	G500S	500	Missense	distal	-3	no	9.867	9.588	EPSD	COSMIC;GDSC	9.540	Down-regulation
Atypical_PIKK_ATM_ATM_ST	P78527	PRKDC	Q13315	ATM	S503	S503F	503	Missense	central	0	yes	9.867	0.000	EPSD	COSMIC	9.540	Loss
Atypical_PIKK_ATM_ATM_ST	P78527	PRKDC	Q13315	ATM	S505	R509H	509	Missense	distal	4	no	10.220	10.156	EPSD	COSMIC	9.540	Down-regulation
Atypical_PIKK_ATM_ATM_ST	P78527	PRKDC	Q13315	ATM	S505	G500C	500	Missense	distal	-5	no	10.220	10.258	EPSD	COSMIC	9.540	Up-regulation
Atypical_PIKK_ATM_ATM_ST	P78527	PRKDC	Q13315	ATM	S505	G500S	500	Missense	distal	-5	no	10.220	10.165	EPSD	COSMIC;GDSC	9.540	Down-regulation
Atypical_PIKK_ATM_ATM_ST	P78527	PRKDC	Q13315	ATM	S505	S503F	503	Missense	proximal	-2	no	10.220	9.320	EPSD	COSMIC	9.540	Loss
Atypical_PIKK_ATM_ATM_ST	P78527	PRKDC	Q13315	ATM	S511	R509H	509	Missense	proximal	-2	no	9.941	9.956	EPSD	COSMIC	9.540	Up-regulation
Atypical_PIKK_ATM_ATM_ST	P78527	PRKDC	Q13315	ATM	S511	R515T	515	Missense	distal	4	no	9.941	9.847	EPSD	COSMIC	9.540	Down-regulation
Atypical_PIKK_ATM_ATM_ST	P78527	PRKDC	Q13315	ATM	S511	V514A	514	Missense	distal	3	no	9.941	9.653	EPSD	COSMIC	9.540	Down-regulation
Atypical_PIKK_ATM_ATM_ST	P78527	PRKDC	Q13315	ATM	S694	L691P	691	Missense	distal	-3	no	10.694	10.681	EPSD	COSMIC	9.540	Down-regulation
Atypical_PIKK_ATM_ATM_ST	P78527	PRKDC	Q13315	ATM	S876	M879T	879	Missense	distal	3	no	10.781	10.606	EPSD	COSMIC	9.540	Down-regulation
Atypical_PIKK_ATM_ATM_ST	P78527	PRKDC	Q13315	ATM	S876	S876L	876	Missense	central	0	yes	10.781	0.000	EPSD	COSMIC	9.540	Loss
Atypical_PIKK_ATM_ATM_ST	P78527	PRKDC	Q13315	ATM	S882	M879T	879	Missense	distal	-3	no	9.878	9.455	EPSD	COSMIC	9.540	Loss
Atypical_PIKK_ATM_ATM_ST	P78527	PRKDC	Q13315	ATM	S882	S876L	876	Missense	distal	-6	no	9.878	9.590	EPSD	COSMIC	9.540	Down-regulation
Atypical_PIKK_ATM_ATM_ST	P78527	PRKDC	Q13315	ATM	T946	T946M	946	Missense	central	0	yes	10.518	0.000	EPSD	COSMIC	9.540	Loss
Atypical_PIKK_ATM_ATM_ST	P78527	PRKDC	Q13315	ATM	S1162	D1167Y	1167	Missense	distal	5	no	9.795	9.774	EPSD	COSMIC	9.540	Down-regulation
Atypical_PIKK_ATM_ATM_ST	P78527	PRKDC	Q13315	ATM	S1162	V1169F	1169	Missense	distal	7	no	9.795	9.807	EPSD	COSMIC	9.540	Up-regulation
Atypical_PIKK_ATM_ATM_ST	P78527	PRKDC	Q13315	ATM	S1546	Q1547H	1547	Missense	proximal	1	no	13.916	-0.993	EPSD	COSMIC	9.540	Loss
Atypical_PIKK_ATM_ATM_ST	P78527	PRKDC	Q13315	ATM	S1546	G1544D	1544	Missense	proximal	-2	no	13.916	14.060	EPSD	COSMIC	9.540	Up-regulation
Atypical_PIKK_ATM_ATM_ST	P78527	PRKDC	Q13315	ATM	S1546	V1550I	1550	Missense	distal	4	no	13.916	14.273	EPSD	COSMIC	9.540	Up-regulation
Atypical_PIKK_ATM_ATM_ST	P78527	PRKDC	Q13315	ATM	S1546	G1548D	1548	Missense	proximal	2	no	13.916	15.154	EPSD	COSMIC	9.540	Up-regulation
Atypical_PIKK_ATM_ATM_ST	P78527	PRKDC	Q13315	ATM	T1733	P1734Q	1734	Missense	proximal	1	no	6.918	11.720	EPSD	COSMIC	9.540	Gain
Atypical_PIKK_ATM_ATM_ST	P78527	PRKDC	Q13315	ATM	T1793	R1788K	1788	Missense	distal	-5	no	12.837	12.678	EPSD	COSMIC	9.540	Down-regulation
Atypical_PIKK_ATM_ATM_ST	P78527	PRKDC	Q13315	ATM	T1793	R1788S	1788	Missense	distal	-5	no	12.837	12.761	EPSD	COSMIC	9.540	Down-regulation
Atypical_PIKK_ATM_ATM_ST	P78527	PRKDC	Q13315	ATM	T1793	L1797F	1797	Missense	distal	4	no	12.837	13.323	EPSD	COSMIC	9.540	Up-regulation
Atypical_PIKK_ATM_ATM_ST	P78527	PRKDC	Q13315	ATM	T1793	G1796S	1796	Missense	distal	3	no	12.837	12.707	EPSD	COSMIC	9.540	Down-regulation
Atypical_PIKK_ATM_ATM_ST	P78527	PRKDC	Q13315	ATM	T1793	E1799G	1799	Missense	distal	6	no	12.837	12.794	EPSD	COSMIC	9.540	Down-regulation
Atypical_PIKK_ATM_ATM_ST	P78527	PRKDC	Q13315	ATM	T1865	L1858V	1858	Missense	distal	-7	no	13.198	13.306	EPSD	COSMIC	9.540	Up-regulation
Atypical_PIKK_ATM_ATM_ST	P78527	PRKDC	Q13315	ATM	T1865	N1859S	1859	Missense	distal	-6	no	13.198	13.314	EPSD	COSMIC	9.540	Up-regulation
Atypical_PIKK_ATM_ATM_ST	P78527	PRKDC	Q13315	ATM	T1865	L1858Q	1858	Missense	distal	-7	no	13.198	13.587	EPSD	COSMIC	9.540	Up-regulation
Atypical_PIKK_ATM_ATM_ST	P78527	PRKDC	Q13315	ATM	T1865	D1864Y	1864	Missense	proximal	-1	no	13.198	13.204	EPSD	COSMIC	9.540	Up-regulation
Atypical_PIKK_ATM_ATM_ST	P78527	PRKDC	Q13315	ATM	T1865	T1868I	1868	Missense	distal	3	no	13.198	13.619	EPSD	COSMIC	9.540	Up-regulation
Atypical_PIKK_ATM_ATM_ST	P78527	PRKDC	Q13315	ATM	T1865	L1858I	1858	Missense	distal	-7	no	13.198	13.122	EPSD	COSMIC	9.540	Down-regulation
Atypical_PIKK_ATM_ATM_ST	P78527	PRKDC	Q13315	ATM	S2041	G2048E	2048	Missense	distal	7	no	14.918	14.873	EPSD	COSMIC	9.540	Down-regulation
Atypical_PIKK_ATM_ATM_ST	P78527	PRKDC	Q13315	ATM	S2041	M2040I	2040	Missense	proximal	-1	no	14.918	14.988	EPSD	COSMIC	9.540	Up-regulation
Atypical_PIKK_ATM_ATM_ST	P78527	PRKDC	Q13315	ATM	S2041	S2046L	2046	Missense	distal	5	no	14.918	15.082	EPSD	COSMIC	9.540	Up-regulation
Atypical_PIKK_ATM_ATM_ST	P78527	PRKDC	Q13315	ATM	S2041	S2037I	2037	Missense	distal	-4	no	14.918	14.206	EPSD	COSMIC	9.540	Down-regulation
Atypical_PIKK_ATM_ATM_ST	P78527	PRKDC	Q13315	ATM	S2041	G2048A	2048	Missense	distal	7	no	14.918	14.907	EPSD	COSMIC	9.540	Down-regulation
Atypical_PIKK_ATM_ATM_ST	P78527	PRKDC	Q13315	ATM	S2041	F2045I	2045	Missense	distal	4	no	14.918	14.753	EPSD	COSMIC	9.540	Down-regulation
Atypical_PIKK_ATM_ATM_ST	P78527	PRKDC	Q13315	ATM	S2041	G2048R	2048	Missense	distal	7	no	14.918	14.911	EPSD	COSMIC	9.540	Down-regulation
Atypical_PIKK_ATM_ATM_ST	P78527	PRKDC	Q13315	ATM	S2041	Q2042K	2042	Missense	proximal	1	no	14.918	8.070	EPSD	COSMIC	9.540	Loss
Atypical_PIKK_ATM_ATM_ST	P78527	PRKDC	Q13315	ATM	S2051	F2045I	2045	Missense	distal	-6	no	9.462	9.592	EPSD	COSMIC	9.540	Gain
Atypical_PIKK_ATM_ATM_ST	P78527	PRKDC	Q13315	ATM	S2051	S2055R	2055	Missense	distal	4	no	9.462	9.644	EPSD	COSMIC	9.540	Gain
Atypical_PIKK_ATM_ATM_ST	P78527	PRKDC	Q13315	ATM	S2051	G2048R	2048	Missense	distal	-3	no	9.462	9.924	EPSD	COSMIC	9.540	Gain
Atypical_PIKK_ATM_ATM_ST	P78527	PRKDC	Q13315	ATM	S2056	A2062T	2062	Missense	distal	6	no	13.918	13.902	EPSD	COSMIC	9.540	Down-regulation
Atypical_PIKK_ATM_ATM_ST	P78527	PRKDC	Q13315	ATM	S2056	P2059A	2059	Missense	distal	3	no	13.918	13.822	EPSD	COSMIC	9.540	Down-regulation
Atypical_PIKK_ATM_ATM_ST	P78527	PRKDC	Q13315	ATM	S2056	D2058N	2058	Missense	proximal	2	no	13.918	12.896	EPSD	COSMIC	9.540	Down-regulation
Atypical_PIKK_ATM_ATM_ST	P78527	PRKDC	Q13315	ATM	S2056	S2055R	2055	Missense	proximal	-1	no	13.918	13.543	EPSD	COSMIC	9.540	Down-regulation
Atypical_PIKK_ATM_ATM_ST	P78527	PRKDC	Q13315	ATM	S2489	E2490K	2490	Missense	proximal	1	no	10.075	9.123	EPSD	COSMIC	9.540	Loss
Atypical_PIKK_ATM_ATM_ST	P78527	PRKDC	Q13315	ATM	T2609	L2616V	2616	Missense	distal	7	no	14.264	14.294	PhosphoSitePlus;EPSD	COSMIC	9.540	Up-regulation
Atypical_PIKK_ATM_ATM_ST	P78527	PRKDC	Q13315	ATM	T2609	M2605I	2605	Missense	distal	-4	no	14.264	14.560	PhosphoSitePlus;EPSD	COSMIC	9.540	Up-regulation
Atypical_PIKK_ATM_ATM_ST	P78527	PRKDC	Q13315	ATM	T2609	L2602F	2602	Missense	distal	-7	no	14.264	14.023	PhosphoSitePlus;EPSD	COSMIC	9.540	Down-regulation
Atypical_PIKK_ATM_ATM_ST	P78527	PRKDC	Q13315	ATM	S2612	L2616V	2616	Missense	distal	4	no	13.458	13.422	EPSD;PhosphoSitePlus	COSMIC	9.540	Down-regulation
Atypical_PIKK_ATM_ATM_ST	P78527	PRKDC	Q13315	ATM	S2612	M2605I	2605	Missense	distal	-7	no	13.458	13.269	EPSD;PhosphoSitePlus	COSMIC	9.540	Down-regulation
Atypical_PIKK_ATM_ATM_ST	P78527	PRKDC	Q13315	ATM	S2612	T2618I	2618	Missense	distal	6	no	13.458	13.428	EPSD;PhosphoSitePlus	COSMIC	9.540	Down-regulation
Atypical_PIKK_ATM_ATM_ST	P78527	PRKDC	Q13315	ATM	S2612	R2619H	2619	Missense	distal	7	no	13.458	13.452	EPSD;PhosphoSitePlus	COSMIC	9.540	Down-regulation
Atypical_PIKK_ATM_ATM_ST	P78527	PRKDC	Q13315	ATM	T2620	T2620N	2620	Missense	central	0	yes	14.495	0.000	EPSD	COSMIC	9.540	Loss
Atypical_PIKK_ATM_ATM_ST	P78527	PRKDC	Q13315	ATM	T2620	L2616V	2616	Missense	distal	-4	no	14.495	14.445	EPSD	COSMIC	9.540	Down-regulation
Atypical_PIKK_ATM_ATM_ST	P78527	PRKDC	Q13315	ATM	T2620	T2618I	2618	Missense	proximal	-2	no	14.495	13.894	EPSD	COSMIC	9.540	Down-regulation
Atypical_PIKK_ATM_ATM_ST	P78527	PRKDC	Q13315	ATM	T2620	R2619H	2619	Missense	proximal	-1	no	14.495	14.665	EPSD	COSMIC	9.540	Up-regulation
Atypical_PIKK_ATM_ATM_ST	P78527	PRKDC	Q13315	ATM	T2620	S2626L	2626	Missense	distal	6	no	14.495	14.439	EPSD	COSMIC	9.540	Down-regulation
Atypical_PIKK_ATM_ATM_ST	P78527	PRKDC	Q13315	ATM	S2624	T2620N	2620	Missense	distal	-4	no	11.108	10.563	EPSD	COSMIC	9.540	Down-regulation
Atypical_PIKK_ATM_ATM_ST	P78527	PRKDC	Q13315	ATM	S2624	T2618I	2618	Missense	distal	-6	no	11.108	10.777	EPSD	COSMIC	9.540	Down-regulation
Atypical_PIKK_ATM_ATM_ST	P78527	PRKDC	Q13315	ATM	S2624	R2619H	2619	Missense	distal	-5	no	11.108	11.081	EPSD	COSMIC	9.540	Down-regulation
Atypical_PIKK_ATM_ATM_ST	P78527	PRKDC	Q13315	ATM	S2624	S2626L	2626	Missense	proximal	2	no	11.108	9.864	EPSD	COSMIC	9.540	Down-regulation
Atypical_PIKK_ATM_ATM_ST	P78527	PRKDC	Q13315	ATM	S2624	R2628C	2628	Missense	distal	4	no	11.108	11.436	EPSD	COSMIC	9.540	Up-regulation
Atypical_PIKK_ATM_ATM_ST	P78527	PRKDC	Q13315	ATM	T2638	R2636M	2636	Missense	proximal	-2	no	14.401	14.406	EPSD;PhosphoSitePlus	COSMIC	9.540	Up-regulation
Atypical_PIKK_ATM_ATM_ST	P78527	PRKDC	Q13315	ATM	T2647	R2653T	2653	Missense	distal	6	no	13.852	13.860	EPSD;PhosphoSitePlus	COSMIC	9.540	Up-regulation
Atypical_PIKK_ATM_ATM_ST	P78527	PRKDC	Q13315	ATM	T2953	Q2954E	2954	Missense	proximal	1	no	15.684	9.787	EPSD	COSMIC	9.540	Down-regulation
Atypical_PIKK_ATM_ATM_ST	P78527	PRKDC	Q13315	ATM	T2953	E2960K	2960	Missense	distal	7	no	15.684	15.710	EPSD	COSMIC	9.540	Up-regulation
Atypical_PIKK_ATM_ATM_ST	P78527	PRKDC	Q13315	ATM	S3215	P3214H	3214	Missense	proximal	-1	no	9.523	9.611	EPSD	COSMIC	9.540	Gain
Atypical_PIKK_ATM_ATM_ST	P78527	PRKDC	Q13315	ATM	S3290	E3295Q	3295	Missense	distal	5	no	11.582	11.807	EPSD	COSMIC	9.540	Up-regulation
Atypical_PIKK_ATM_ATM_ST	P78527	PRKDC	Q13315	ATM	S3290	R3287Q	3287	Missense	distal	-3	no	11.582	10.807	EPSD	COSMIC	9.540	Down-regulation
Atypical_PIKK_ATM_ATM_ST	P78527	PRKDC	Q13315	ATM	S3290	Q3296H	3296	Missense	distal	6	no	11.582	11.571	EPSD	COSMIC	9.540	Down-regulation
Atypical_PIKK_ATM_ATM_ST	P78527	PRKDC	Q13315	ATM	S3290	C3293Y	3293	Missense	distal	3	no	11.582	11.403	EPSD	COSMIC	9.540	Down-regulation
Atypical_PIKK_ATM_ATM_ST	P78527	PRKDC	Q13315	ATM	S3290	R3289W	3289	Missense	proximal	-1	no	11.582	11.579	EPSD	COSMIC	9.540	Down-regulation
Atypical_PIKK_ATM_ATM_ST	P78527	PRKDC	Q13315	ATM	S3290	H3285Y	3285	Missense	distal	-5	no	11.582	11.558	EPSD	COSMIC	9.540	Down-regulation
Atypical_PIKK_ATM_ATM_ST	P78527	PRKDC	Q13315	ATM	S3290	S3294F	3294	Missense	distal	4	no	11.582	12.410	EPSD	COSMIC	9.540	Up-regulation
Atypical_PIKK_ATM_ATM_ST	P78527	PRKDC	Q13315	ATM	S3294	E3295Q	3295	Missense	proximal	1	no	6.440	12.337	EPSD	COSMIC	9.540	Gain
Atypical_PIKK_ATM_ATM_ST	P78527	PRKDC	Q13315	ATM	S3366	S3367P	3367	Missense	proximal	1	no	2.650	9.626	EPSD	COSMIC	9.540	Gain
Atypical_PIKK_ATM_ATM_ST	P78527	PRKDC	Q13315	ATM	S3367	G3364V	3364	Missense	distal	-3	no	11.328	11.468	EPSD	COSMIC	9.540	Up-regulation
Atypical_PIKK_ATM_ATM_ST	P78527	PRKDC	Q13315	ATM	S3367	S3367P	3367	Missense	central	0	yes	11.328	0.000	EPSD	COSMIC	9.540	Loss
Atypical_PIKK_ATM_ATM_ST	P78527	PRKDC	Q13315	ATM	S3367	S3366T	3366	Missense	proximal	-1	no	11.328	11.338	EPSD	COSMIC	9.540	Up-regulation
Atypical_PIKK_ATM_ATM_ST	P78527	PRKDC	Q13315	ATM	S3367	L3362V	3362	Missense	distal	-5	no	11.328	11.418	EPSD	COSMIC	9.540	Up-regulation
Atypical_PIKK_ATM_ATM_ST	P78527	PRKDC	Q13315	ATM	S3370	G3364V	3364	Missense	distal	-6	no	10.079	10.024	EPSD	COSMIC	9.540	Down-regulation
Atypical_PIKK_ATM_ATM_ST	P78527	PRKDC	Q13315	ATM	S3370	S3367P	3367	Missense	distal	-3	no	10.079	10.275	EPSD	COSMIC	9.540	Up-regulation
Atypical_PIKK_ATM_ATM_ST	P78527	PRKDC	Q13315	ATM	S3370	S3366T	3366	Missense	distal	-4	no	10.079	9.696	EPSD	COSMIC	9.540	Down-regulation
Atypical_PIKK_ATM_ATM_ST	P78527	PRKDC	Q13315	ATM	S3370	S3367T	3367	Missense	distal	-3	no	10.079	10.011	EPSD	COSMIC	9.540	Down-regulation
Atypical_PIKK_ATM_ATM_ST	P78527	PRKDC	Q13315	ATM	S3370	A3375T	3375	Missense	distal	5	no	10.079	10.014	EPSD	COSMIC	9.540	Down-regulation
Atypical_PIKK_ATM_ATM_ST	P78527	PRKDC	Q13315	ATM	S3436	Q3440L	3440	Missense	distal	4	no	9.919	10.227	EPSD	COSMIC	9.540	Up-regulation
Atypical_PIKK_ATM_ATM_ST	P78527	PRKDC	Q13315	ATM	S3436	V3433G	3433	Missense	distal	-3	no	9.919	9.778	EPSD	COSMIC	9.540	Down-regulation
Atypical_PIKK_ATM_ATM_ST	P78527	PRKDC	Q13315	ATM	S3436	I3434T	3434	Missense	proximal	-2	no	9.919	10.520	EPSD	COSMIC	9.540	Up-regulation
Atypical_PIKK_ATM_ATM_ST	P78527	PRKDC	Q13315	ATM	S3436	A3437S	3437	Missense	proximal	1	no	9.919	5.015	EPSD	COSMIC	9.540	Loss
Atypical_PIKK_ATM_ATM_ST	P78527	PRKDC	Q13315	ATM	S3436	A3441E	3441	Missense	distal	5	no	9.919	9.700	EPSD	COSMIC	9.540	Down-regulation
Atypical_PIKK_ATM_ATM_ST	P78527	PRKDC	Q13315	ATM	S3436	A3441V	3441	Missense	distal	5	no	9.919	10.083	EPSD	COSMIC	9.540	Up-regulation
Atypical_PIKK_ATM_ATM_ST	P78527	PRKDC	Q13315	ATM	S3821	A3826V	3826	Missense	distal	5	no	14.735	14.899	EPSD	COSMIC	9.540	Up-regulation
Atypical_PIKK_ATM_ATM_ST	P78527	PRKDC	Q13315	ATM	S3821	L3815R	3815	Missense	distal	-6	no	14.735	14.843	EPSD	COSMIC	9.540	Up-regulation
Atypical_PIKK_ATM_ATM_ST	P78527	PRKDC	Q13315	ATM	S3821	A3826T	3826	Missense	distal	5	no	14.735	14.670	EPSD	COSMIC	9.540	Down-regulation
Atypical_PIKK_ATM_ATM_ST	P78527	PRKDC	Q13315	ATM	S3821	L3816P	3816	Missense	distal	-5	no	14.735	14.716	EPSD	COSMIC	9.540	Down-regulation
Atypical_PIKK_ATM_ATM_ST	P78527	PRKDC	Q13315	ATM	S3821	S3821P	3821	Missense	central	0	yes	14.735	0.000	EPSD	COSMIC	9.540	Loss
Atypical_PIKK_ATM_ATM_ST	P78527	PRKDC	Q13315	ATM	S3893	E3895K	3895	Missense	proximal	2	no	12.367	11.037	EPSD	COSMIC	9.540	Down-regulation
Atypical_PIKK_ATM_ATM_ST	P78527	PRKDC	Q13315	ATM	S3893	F3897C	3897	Missense	distal	4	no	12.367	12.049	EPSD	COSMIC	9.540	Down-regulation
Atypical_PIKK_ATM_ATM_ST	P78527	PRKDC	Q13315	ATM	S3893	A3899V	3899	Missense	distal	6	no	12.367	12.337	EPSD	COSMIC	9.540	Down-regulation
Atypical_PIKK_ATM_ATM_ST	P78527	PRKDC	Q13315	ATM	S3893	P3894L	3894	Missense	proximal	1	no	12.367	10.813	EPSD	COSMIC	9.540	Down-regulation
Atypical_PIKK_ATM_ATM_ST	P78527	PRKDC	Q13315	ATM	S3893	S3891C	3891	Missense	proximal	-2	no	12.367	11.906	EPSD	COSMIC	9.540	Down-regulation
Atypical_PIKK_ATM_ATM_ST	P78527	PRKDC	Q13315	ATM	T3950	G3947D	3947	Missense	distal	-3	no	10.459	10.427	EPSD	COSMIC	9.540	Down-regulation
Atypical_PIKK_ATM_ATM_ST	P78527	PRKDC	Q13315	ATM	T3950	G3947V	3947	Missense	distal	-3	no	10.459	10.599	EPSD	COSMIC	9.540	Up-regulation
Atypical_PIKK_ATM_ATM_ST	P78527	PRKDC	Q13315	ATM	T3950	S3948F	3948	Missense	proximal	-2	no	10.459	9.559	EPSD	COSMIC	9.540	Down-regulation
Atypical_PIKK_ATM_ATM_ST	P78527	PRKDC	Q13315	ATM	T3950	H3944N	3944	Missense	distal	-6	no	10.459	10.522	EPSD	COSMIC	9.540	Up-regulation
Atypical_PIKK_ATM_ATM_ST	P78527	PRKDC	Q13315	ATM	T4102	V4104L	4104	Missense	proximal	2	no	14.192	13.840	EPSD	COSMIC	9.540	Down-regulation
Atypical_PIKK_ATM_ATM_ST	Q99801	NKX3-1	Q13315	ATM	S48	Q49H	49	Missense	proximal	1	no	12.696	-2.213	EPSD	COSMIC	9.540	Loss
Atypical_PIKK_ATM_ATM_ST	Q99801	NKX3-1	Q13315	ATM	S48	R45S	45	Missense	distal	-3	no	12.696	11.956	EPSD	COSMIC	9.540	Down-regulation
Atypical_PIKK_ATM_ATM_ST	Q99801	NKX3-1	Q13315	ATM	S48	R52S	52	Missense	distal	4	no	12.696	12.514	EPSD	COSMIC	9.540	Down-regulation
Atypical_PIKK_ATM_ATM_ST	Q99801	NKX3-1	Q13315	ATM	T134	V136I	136	Missense	proximal	2	no	13.822	14.030	EPSD;PhosphoSitePlus	COSMIC	9.540	Up-regulation
Atypical_PIKK_ATM_ATM_ST	Q99801	NKX3-1	Q13315	ATM	T134	A129G	129	Missense	distal	-5	no	13.822	13.885	EPSD;PhosphoSitePlus	COSMIC	9.540	Up-regulation
Atypical_PIKK_ATM_ATM_ST	Q99801	NKX3-1	Q13315	ATM	T134	H133D	133	Missense	proximal	-1	no	13.822	13.972	EPSD;PhosphoSitePlus	COSMIC	9.540	Up-regulation
Atypical_PIKK_ATM_ATM_ST	Q99801	NKX3-1	Q13315	ATM	T134	A129P	129	Missense	distal	-5	no	13.822	13.834	EPSD;PhosphoSitePlus	COSMIC	9.540	Up-regulation
Atypical_PIKK_ATM_ATM_ST	Q99801	NKX3-1	Q13315	ATM	T134	V136M	136	Missense	proximal	2	no	13.822	13.657	EPSD;PhosphoSitePlus	COSMIC	9.540	Down-regulation
Atypical_PIKK_ATM_ATM_ST	Q99801	NKX3-1	Q13315	ATM	T166	I170T	170	Missense	distal	4	no	14.014	13.439	PhosphoSitePlus;EPSD	COSMIC	9.540	Down-regulation
Atypical_PIKK_ATM_ATM_ST	Q99801	NKX3-1	Q13315	ATM	T166	E165K	165	Missense	proximal	-1	no	14.014	13.612	PhosphoSitePlus;EPSD	COSMIC	9.540	Down-regulation
Atypical_PIKK_ATM_ATM_ST	Q99801	NKX3-1	Q13315	ATM	T166	F172L	172	Missense	distal	6	no	14.014	14.034	PhosphoSitePlus;EPSD	COSMIC	9.540	Up-regulation
Atypical_PIKK_ATM_ATM_ST	Q12888	TP53BP1	Q13315	ATM	S105	V107A	107	Missense	proximal	2	no	12.866	13.175	EPSD	COSMIC	9.540	Up-regulation
Atypical_PIKK_ATM_ATM_ST	Q12888	TP53BP1	Q13315	ATM	S166	A160V	160	Missense	distal	-6	no	14.193	13.957	EPSD	COSMIC	9.540	Down-regulation
Atypical_PIKK_ATM_ATM_ST	Q12888	TP53BP1	Q13315	ATM	S233	S232F	232	Missense	proximal	-1	no	10.013	9.587	EPSD	COSMIC	9.540	Down-regulation
Atypical_PIKK_ATM_ATM_ST	Q12888	TP53BP1	Q13315	ATM	S233	A229S	229	Missense	distal	-4	no	10.013	10.523	EPSD	COSMIC	9.540	Up-regulation
Atypical_PIKK_ATM_ATM_ST	Q12888	TP53BP1	Q13315	ATM	S233	P227L	227	Missense	distal	-6	no	10.013	9.784	EPSD	COSMIC	9.540	Down-regulation
Atypical_PIKK_ATM_ATM_ST	Q12888	TP53BP1	Q13315	ATM	S243	K244E	244	Missense	proximal	1	no	9.157	10.109	EPSD	COSMIC	9.540	Gain
Atypical_PIKK_ATM_ATM_ST	Q12888	TP53BP1	Q13315	ATM	S259	P254S	254	Missense	distal	-5	no	9.579	9.576	EPSD	COSMIC	9.540	Down-regulation
Atypical_PIKK_ATM_ATM_ST	Q12888	TP53BP1	Q13315	ATM	S294	L289V	289	Missense	distal	-5	no	11.772	11.863	EPSD	COSMIC	9.540	Up-regulation
Atypical_PIKK_ATM_ATM_ST	Q12888	TP53BP1	Q13315	ATM	S294	Q292H	292	Missense	proximal	-2	no	11.772	11.469	EPSD	COSMIC	9.540	Down-regulation
Atypical_PIKK_ATM_ATM_ST	Q12888	TP53BP1	Q13315	ATM	T302	F307V	307	Missense	distal	5	no	15.386	15.292	EPSD	COSMIC	9.540	Down-regulation
Atypical_PIKK_ATM_ATM_ST	Q12888	TP53BP1	Q13315	ATM	T302	F307L	307	Missense	distal	5	no	15.386	15.245	EPSD	COSMIC	9.540	Down-regulation
Atypical_PIKK_ATM_ATM_ST	Q12888	TP53BP1	Q13315	ATM	S366	S359F	359	Missense	distal	-7	no	11.215	10.385	EPSD	COSMIC	9.540	Down-regulation
Atypical_PIKK_ATM_ATM_ST	Q12888	TP53BP1	Q13315	ATM	S366	V363F	363	Missense	distal	-3	no	11.215	11.868	EPSD	COSMIC	9.540	Up-regulation
Atypical_PIKK_ATM_ATM_ST	Q12888	TP53BP1	Q13315	ATM	S366	D368N	368	Missense	proximal	2	no	11.215	10.193	EPSD	COSMIC	9.540	Down-regulation
Atypical_PIKK_ATM_ATM_ST	Q12888	TP53BP1	Q13315	ATM	S380	P381L	381	Missense	proximal	1	no	9.831	8.277	EPSD	COSMIC	9.540	Loss
Atypical_PIKK_ATM_ATM_ST	Q12888	TP53BP1	Q13315	ATM	S380	R387K	387	Missense	distal	7	no	9.831	9.819	EPSD	COSMIC	9.540	Down-regulation
Atypical_PIKK_ATM_ATM_ST	Q12888	TP53BP1	Q13315	ATM	S380	P374S	374	Missense	distal	-6	no	9.831	9.890	EPSD	COSMIC	9.540	Up-regulation
Atypical_PIKK_ATM_ATM_ST	Q12888	TP53BP1	Q13315	ATM	S523	T519A	519	Missense	distal	-4	no	14.307	14.180	EPSD	COSMIC	9.540	Down-regulation
Atypical_PIKK_ATM_ATM_ST	Q12888	TP53BP1	Q13315	ATM	S525	T519A	519	Missense	distal	-6	no	10.644	10.693	EPSD	COSMIC	9.540	Up-regulation
Atypical_PIKK_ATM_ATM_ST	Q12888	TP53BP1	Q13315	ATM	T543	T548A	548	Missense	distal	5	no	13.539	13.603	EPSD	COSMIC	9.540	Up-regulation
Atypical_PIKK_ATM_ATM_ST	Q12888	TP53BP1	Q13315	ATM	T548	T548A	548	Missense	central	0	yes	10.427	0.000	EPSD	COSMIC	9.540	Loss
Atypical_PIKK_ATM_ATM_ST	Q12888	TP53BP1	Q13315	ATM	S625	D622N	622	Missense	distal	-3	no	13.767	13.494	EPSD	COSMIC	9.540	Down-regulation
Atypical_PIKK_ATM_ATM_ST	Q12888	TP53BP1	Q13315	ATM	S625	S623L	623	Missense	proximal	-2	no	13.767	13.377	EPSD	COSMIC	9.540	Down-regulation
Atypical_PIKK_ATM_ATM_ST	Q12888	TP53BP1	Q13315	ATM	S630	S623L	623	Missense	distal	-7	no	10.478	9.891	EPSD	COSMIC	9.540	Down-regulation
Atypical_PIKK_ATM_ATM_ST	Q12888	TP53BP1	Q13315	ATM	S727	D726Y	726	Missense	proximal	-1	no	12.288	12.294	EPSD	COSMIC	9.540	Up-regulation
Atypical_PIKK_ATM_ATM_ST	Q12888	TP53BP1	Q13315	ATM	S727	K730T	730	Missense	distal	3	no	12.288	12.256	EPSD	COSMIC	9.540	Down-regulation
Atypical_PIKK_ATM_ATM_ST	Q12888	TP53BP1	Q13315	ATM	S784	D783N	783	Missense	proximal	-1	no	14.047	14.046	EPSD	COSMIC	9.540	Down-regulation
Atypical_PIKK_ATM_ATM_ST	Q12888	TP53BP1	Q13315	ATM	S784	D789N	789	Missense	distal	5	no	14.047	13.935	EPSD	COSMIC	9.540	Down-regulation
Atypical_PIKK_ATM_ATM_ST	Q12888	TP53BP1	Q13315	ATM	S831	D829E	829	Missense	proximal	-2	no	15.548	16.027	EPSD	COSMIC	9.540	Up-regulation
Atypical_PIKK_ATM_ATM_ST	Q12888	TP53BP1	Q13315	ATM	S831	S830F	830	Missense	proximal	-1	no	15.548	15.121	EPSD	COSMIC	9.540	Down-regulation
Atypical_PIKK_ATM_ATM_ST	Q12888	TP53BP1	Q13315	ATM	S892	S899R	899	Missense	distal	7	no	13.741	13.775	EPSD	COSMIC	9.540	Up-regulation
Atypical_PIKK_ATM_ATM_ST	Q12888	TP53BP1	Q13315	ATM	S892	S888A	888	Missense	distal	-4	no	13.741	13.231	EPSD	COSMIC	9.540	Down-regulation
Atypical_PIKK_ATM_ATM_ST	Q12888	TP53BP1	Q13315	ATM	S892	S894R	894	Missense	proximal	2	no	13.741	12.743	EPSD	COSMIC	9.540	Down-regulation
Atypical_PIKK_ATM_ATM_ST	Q12888	TP53BP1	Q13315	ATM	S970	H964Y	964	Missense	distal	-6	no	11.215	11.145	EPSD	COSMIC	9.540	Down-regulation
Atypical_PIKK_ATM_ATM_ST	Q12888	TP53BP1	Q13315	ATM	S970	K972E	972	Missense	proximal	2	no	11.215	12.546	EPSD	COSMIC	9.540	Up-regulation
Atypical_PIKK_ATM_ATM_ST	Q12888	TP53BP1	Q13315	ATM	S970	S975F	975	Missense	distal	5	no	11.215	11.522	EPSD	COSMIC	9.540	Up-regulation
Atypical_PIKK_ATM_ATM_ST	Q12888	TP53BP1	Q13315	ATM	S1028	S1028I	1028	Missense	central	0	yes	10.733	0.000	EPSD	COSMIC	9.540	Loss
Atypical_PIKK_ATM_ATM_ST	Q12888	TP53BP1	Q13315	ATM	S1028	V1026A	1026	Missense	proximal	-2	no	10.733	11.210	EPSD	COSMIC	9.540	Up-regulation
Atypical_PIKK_ATM_ATM_ST	Q12888	TP53BP1	Q13315	ATM	S1028	A1027G	1027	Missense	proximal	-1	no	10.733	10.702	EPSD	COSMIC	9.540	Down-regulation
Atypical_PIKK_ATM_ATM_ST	Q12888	TP53BP1	Q13315	ATM	S1068	S1068F	1068	Missense	central	0	yes	13.473	0.000	EPSD	COSMIC	9.540	Loss
Atypical_PIKK_ATM_ATM_ST	Q12888	TP53BP1	Q13315	ATM	S1068	F1065I	1065	Missense	distal	-3	no	13.473	13.071	EPSD	COSMIC	9.540	Down-regulation
Atypical_PIKK_ATM_ATM_ST	Q12888	TP53BP1	Q13315	ATM	S1086	P1089L	1089	Missense	distal	3	no	14.251	14.381	EPSD	COSMIC	9.540	Up-regulation
Atypical_PIKK_ATM_ATM_ST	Q12888	TP53BP1	Q13315	ATM	S1104	S1101F	1101	Missense	distal	-3	no	13.840	14.911	EPSD	COSMIC	9.540	Up-regulation
Atypical_PIKK_ATM_ATM_ST	Q12888	TP53BP1	Q13315	ATM	S1148	K1141Q	1141	Missense	distal	-7	no	16.532	16.646	EPSD	COSMIC	9.540	Up-regulation
Atypical_PIKK_ATM_ATM_ST	Q12888	TP53BP1	Q13315	ATM	T1171	T1173S	1173	Missense	proximal	2	no	13.352	13.614	EPSD	COSMIC	9.540	Up-regulation
Atypical_PIKK_ATM_ATM_ST	Q12888	TP53BP1	Q13315	ATM	T1270	E1271Q	1271	Missense	proximal	1	no	6.505	12.401	EPSD	COSMIC	9.540	Gain
Atypical_PIKK_ATM_ATM_ST	Q12888	TP53BP1	Q13315	ATM	T1273	E1271Q	1271	Missense	proximal	-2	no	9.816	9.512	EPSD	COSMIC	9.540	Loss
Atypical_PIKK_ATM_ATM_ST	Q12888	TP53BP1	Q13315	ATM	T1273	P1276L	1276	Missense	distal	3	no	9.816	9.947	EPSD	COSMIC	9.540	Up-regulation
Atypical_PIKK_ATM_ATM_ST	Q12888	TP53BP1	Q13315	ATM	T1273	E1266Q	1266	Missense	distal	-7	no	9.816	9.262	EPSD	COSMIC	9.540	Loss
Atypical_PIKK_ATM_ATM_ST	Q12888	TP53BP1	Q13315	ATM	T1273	E1272K	1272	Missense	proximal	-1	no	9.816	9.413	EPSD	COSMIC	9.540	Loss
Atypical_PIKK_ATM_ATM_ST	Q12888	TP53BP1	Q13315	ATM	S1288	T1285S	1285	Missense	distal	-3	no	11.610	11.678	EPSD	COSMIC	9.540	Up-regulation
Atypical_PIKK_ATM_ATM_ST	Q12888	TP53BP1	Q13315	ATM	S1288	Q1291E	1291	Missense	distal	3	no	11.610	11.351	EPSD	COSMIC	9.540	Down-regulation
Atypical_PIKK_ATM_ATM_ST	Q12888	TP53BP1	Q13315	ATM	S1290	T1285S	1285	Missense	distal	-5	no	17.431	17.520	EPSD	COSMIC	9.540	Up-regulation
Atypical_PIKK_ATM_ATM_ST	Q12888	TP53BP1	Q13315	ATM	S1290	Q1291E	1291	Missense	proximal	1	no	17.431	11.534	EPSD	COSMIC	9.540	Down-regulation
Atypical_PIKK_ATM_ATM_ST	Q12888	TP53BP1	Q13315	ATM	S1317	R1314H	1314	Missense	distal	-3	no	10.076	9.431	EPSD	COSMIC	9.540	Loss
Atypical_PIKK_ATM_ATM_ST	Q12888	TP53BP1	Q13315	ATM	S1320	R1314H	1314	Missense	distal	-6	no	10.039	10.040	EPSD	COSMIC	9.540	Up-regulation
Atypical_PIKK_ATM_ATM_ST	Q12888	TP53BP1	Q13315	ATM	S1368	G1371R	1371	Missense	distal	3	no	14.035	14.090	EPSD	COSMIC	9.540	Up-regulation
Atypical_PIKK_ATM_ATM_ST	Q12888	TP53BP1	Q13315	ATM	S1430	S1435F	1435	Missense	distal	5	no	10.427	10.733	EPSD	COSMIC	9.540	Up-regulation
Atypical_PIKK_ATM_ATM_ST	Q12888	TP53BP1	Q13315	ATM	S1462	R1458H	1458	Missense	distal	-4	no	11.998	12.129	EPSD	COSMIC	9.540	Up-regulation
Atypical_PIKK_ATM_ATM_ST	Q12888	TP53BP1	Q13315	ATM	S1481	S1485F	1485	Missense	distal	4	no	10.215	11.043	EPSD	COSMIC	9.540	Up-regulation
Atypical_PIKK_ATM_ATM_ST	Q12888	TP53BP1	Q13315	ATM	S1481	S1480F	1480	Missense	proximal	-1	no	10.215	9.789	EPSD	COSMIC	9.540	Down-regulation
Atypical_PIKK_ATM_ATM_ST	Q12888	TP53BP1	Q13315	ATM	S1554	G1556E	1556	Missense	proximal	2	no	8.650	10.019	EPSD	COSMIC	9.540	Gain
Atypical_PIKK_ATM_ATM_ST	Q12888	TP53BP1	Q13315	ATM	S1634	S1635P	1635	Missense	proximal	1	no	3.012	9.987	EPSD	COSMIC	9.540	Gain
Atypical_PIKK_ATM_ATM_ST	Q12888	TP53BP1	Q13315	ATM	S1635	S1635P	1635	Missense	central	0	yes	9.886	0.000	EPSD	COSMIC	9.540	Loss
Atypical_PIKK_ATM_ATM_ST	Q12888	TP53BP1	Q13315	ATM	S1635	S1635F	1635	Missense	central	0	yes	9.886	0.000	EPSD	COSMIC	9.540	Loss
Atypical_PIKK_ATM_ATM_ST	Q12888	TP53BP1	Q13315	ATM	S1642	S1643G	1643	Missense	proximal	1	no	4.488	9.791	EPSD	COSMIC	9.540	Gain
Atypical_PIKK_ATM_ATM_ST	Q12888	TP53BP1	Q13315	ATM	T1648	S1643G	1643	Missense	distal	-5	no	9.890	9.944	EPSD	COSMIC	9.540	Up-regulation
Atypical_PIKK_ATM_ATM_ST	Q12888	TP53BP1	Q13315	ATM	T1648	R1651Q	1651	Missense	distal	3	no	9.890	9.787	EPSD	COSMIC	9.540	Down-regulation
Atypical_PIKK_ATM_ATM_ST	Q12888	TP53BP1	Q13315	ATM	T1650	R1651Q	1651	Missense	proximal	1	no	7.568	14.219	EPSD	COSMIC	9.540	Gain
Atypical_PIKK_ATM_ATM_ST	Q12888	TP53BP1	Q13315	ATM	S1656	P1657S	1657	Missense	proximal	1	no	10.215	3.239	EPSD	COSMIC	9.540	Loss
Atypical_PIKK_ATM_ATM_ST	Q12888	TP53BP1	Q13315	ATM	S1656	A1659V	1659	Missense	distal	3	no	10.215	10.503	EPSD	COSMIC	9.540	Up-regulation
Atypical_PIKK_ATM_ATM_ST	Q12888	TP53BP1	Q13315	ATM	S1656	R1651Q	1651	Missense	distal	-5	no	10.215	10.005	EPSD	COSMIC	9.540	Down-regulation
Atypical_PIKK_ATM_ATM_ST	Q12888	TP53BP1	Q13315	ATM	S1656	M1661T	1661	Missense	distal	5	no	10.215	10.013	EPSD	COSMIC	9.540	Down-regulation
Atypical_PIKK_ATM_ATM_ST	Q12888	TP53BP1	Q13315	ATM	S1673	E1676Q	1676	Missense	distal	3	no	10.010	10.269	EPSD	COSMIC	9.540	Up-regulation
Atypical_PIKK_ATM_ATM_ST	Q12888	TP53BP1	Q13315	ATM	S1673	P1679S	1679	Missense	distal	6	no	10.010	10.021	EPSD	COSMIC	9.540	Up-regulation
Atypical_PIKK_ATM_ATM_ST	Q12888	TP53BP1	Q13315	ATM	S1678	E1676Q	1676	Missense	proximal	-2	no	11.099	10.794	EPSD	COSMIC	9.540	Down-regulation
Atypical_PIKK_ATM_ATM_ST	Q12888	TP53BP1	Q13315	ATM	S1678	P1679S	1679	Missense	proximal	1	no	11.099	4.124	EPSD	COSMIC	9.540	Loss
Atypical_PIKK_ATM_ATM_ST	Q12888	TP53BP1	Q13315	ATM	S1778	T1776A	1776	Missense	proximal	-2	no	12.854	12.754	EPSD;PhosphoSitePlus	COSMIC	9.540	Down-regulation
Atypical_PIKK_ATM_ATM_ST	P08047	SP1	Q13315	ATM	S56	S59Y	59	Missense	distal	3	no	15.449	15.690	PhosphoSitePlus;EPSD	COSMIC	9.540	Up-regulation
Atypical_PIKK_ATM_ATM_ST	P08047	SP1	Q13315	ATM	S73	E72K	72	Missense	proximal	-1	no	11.367	10.964	EPSD	COSMIC	9.540	Down-regulation
Atypical_PIKK_ATM_ATM_ST	P08047	SP1	Q13315	ATM	S73	N79K	79	Missense	distal	6	no	11.367	11.356	EPSD	COSMIC	9.540	Down-regulation
Atypical_PIKK_ATM_ATM_ST	P08047	SP1	Q13315	ATM	S81	Q86R	86	Missense	distal	5	no	11.491	11.603	EPSD	COSMIC	9.540	Up-regulation
Atypical_PIKK_ATM_ATM_ST	P08047	SP1	Q13315	ATM	S81	N79K	79	Missense	proximal	-2	no	11.491	11.275	EPSD	COSMIC	9.540	Down-regulation
Atypical_PIKK_ATM_ATM_ST	P08047	SP1	Q13315	ATM	S81	P84L	84	Missense	distal	3	no	11.491	11.621	EPSD	COSMIC	9.540	Up-regulation
Atypical_PIKK_ATM_ATM_ST	P08047	SP1	Q13315	ATM	S85	Q86R	86	Missense	proximal	1	no	13.102	6.451	EPSD	COSMIC	9.540	Loss
Atypical_PIKK_ATM_ATM_ST	P08047	SP1	Q13315	ATM	S85	T90A	90	Missense	distal	5	no	13.102	13.167	EPSD	COSMIC	9.540	Up-regulation
Atypical_PIKK_ATM_ATM_ST	P08047	SP1	Q13315	ATM	S85	N79K	79	Missense	distal	-6	no	13.102	13.105	EPSD	COSMIC	9.540	Up-regulation
Atypical_PIKK_ATM_ATM_ST	P08047	SP1	Q13315	ATM	S85	P84L	84	Missense	proximal	-1	no	13.102	13.259	EPSD	COSMIC	9.540	Up-regulation
Atypical_PIKK_ATM_ATM_ST	P08047	SP1	Q13315	ATM	T98	A97V	97	Missense	proximal	-1	no	13.316	13.053	EPSD	COSMIC	9.540	Down-regulation
Atypical_PIKK_ATM_ATM_ST	P08047	SP1	Q13315	ATM	T98	A104V	104	Missense	distal	6	no	13.316	13.285	EPSD	COSMIC	9.540	Down-regulation
Atypical_PIKK_ATM_ATM_ST	P08047	SP1	Q13315	ATM	T98	T98A	98	Missense	central	0	yes	13.316	0.000	EPSD	COSMIC;GDSC;CCLE	9.540	Loss
Atypical_PIKK_ATM_ATM_ST	P08047	SP1	Q13315	ATM	S101	A97V	97	Missense	distal	-4	no	12.851	12.371	EPSD;PhosphoSitePlus	COSMIC	9.540	Down-regulation
Atypical_PIKK_ATM_ATM_ST	P08047	SP1	Q13315	ATM	S101	A104V	104	Missense	distal	3	no	12.851	13.139	EPSD;PhosphoSitePlus	COSMIC	9.540	Up-regulation
Atypical_PIKK_ATM_ATM_ST	P08047	SP1	Q13315	ATM	S101	T98A	98	Missense	distal	-3	no	12.851	12.473	EPSD;PhosphoSitePlus	COSMIC;GDSC;CCLE	9.540	Down-regulation
Atypical_PIKK_ATM_ATM_ST	P08047	SP1	Q13315	ATM	S698	H700Y	700	Missense	proximal	2	no	9.855	9.676	EPSD	COSMIC	9.540	Down-regulation
Atypical_PIKK_ATM_ATM_ST	P08047	SP1	Q13315	ATM	T739	T739P	739	Missense	central	0	yes	9.655	0.000	EPSD	COSMIC	9.540	Loss
Atypical_PIKK_ATM_ATM_ST	P08047	SP1	Q13315	ATM	T739	T746P	746	Missense	distal	7	no	9.655	9.657	EPSD	COSMIC	9.540	Up-regulation
Atypical_PIKK_ATM_ATM_ST	P08047	SP1	Q13315	ATM	T739	S732L	732	Missense	distal	-7	no	9.655	9.067	EPSD	COSMIC	9.540	Loss
Atypical_PIKK_ATM_ATM_ST	O95071	UBR5	Q13315	ATM	S117	R122M	122	Missense	distal	5	no	9.782	9.801	EPSD	COSMIC	9.540	Up-regulation
Atypical_PIKK_ATM_ATM_ST	O95071	UBR5	Q13315	ATM	S117	W112S	112	Missense	distal	-5	no	9.782	9.540	EPSD	COSMIC;GDSC;CCLE	9.540	Down-regulation
Atypical_PIKK_ATM_ATM_ST	O95071	UBR5	Q13315	ATM	S174	R167Q	167	Missense	distal	-7	no	14.833	15.033	EPSD;PhosphoSitePlus	COSMIC	9.540	Up-regulation
Atypical_PIKK_ATM_ATM_ST	O95071	UBR5	Q13315	ATM	S174	Q175P	175	Missense	proximal	1	no	14.833	10.031	EPSD;PhosphoSitePlus	COSMIC	9.540	Down-regulation
Atypical_PIKK_ATM_ATM_ST	O95071	UBR5	Q13315	ATM	S191	I190V	190	Missense	proximal	-1	no	14.811	14.608	PhosphoSitePlus;EPSD	COSMIC	9.540	Down-regulation
Atypical_PIKK_ATM_ATM_ST	O95071	UBR5	Q13315	ATM	T348	N342S	342	Missense	distal	-6	no	9.869	9.985	EPSD	COSMIC	9.540	Up-regulation
Atypical_PIKK_ATM_ATM_ST	O95071	UBR5	Q13315	ATM	T348	S355C	355	Missense	distal	7	no	9.869	9.921	EPSD	COSMIC	9.540	Up-regulation
Atypical_PIKK_ATM_ATM_ST	O95071	UBR5	Q13315	ATM	T348	V350A	350	Missense	proximal	2	no	9.869	10.178	EPSD	COSMIC	9.540	Up-regulation
Atypical_PIKK_ATM_ATM_ST	O95071	UBR5	Q13315	ATM	T348	K346R	346	Missense	proximal	-2	no	9.869	9.821	EPSD	COSMIC	9.540	Down-regulation
Atypical_PIKK_ATM_ATM_ST	O95071	UBR5	Q13315	ATM	T348	V354I	354	Missense	distal	6	no	9.869	9.852	EPSD	COSMIC	9.540	Down-regulation
Atypical_PIKK_ATM_ATM_ST	O95071	UBR5	Q13315	ATM	T348	P353S	353	Missense	distal	5	no	9.869	9.687	EPSD	COSMIC	9.540	Down-regulation
Atypical_PIKK_ATM_ATM_ST	O95071	UBR5	Q13315	ATM	S352	S355C	355	Missense	distal	3	no	10.872	11.293	EPSD	COSMIC	9.540	Up-regulation
Atypical_PIKK_ATM_ATM_ST	O95071	UBR5	Q13315	ATM	S352	V350A	350	Missense	proximal	-2	no	10.872	11.349	EPSD	COSMIC	9.540	Up-regulation
Atypical_PIKK_ATM_ATM_ST	O95071	UBR5	Q13315	ATM	S352	K346R	346	Missense	distal	-6	no	10.872	10.805	EPSD	COSMIC	9.540	Down-regulation
Atypical_PIKK_ATM_ATM_ST	O95071	UBR5	Q13315	ATM	S352	V354I	354	Missense	proximal	2	no	10.872	11.079	EPSD	COSMIC	9.540	Up-regulation
Atypical_PIKK_ATM_ATM_ST	O95071	UBR5	Q13315	ATM	S352	P353S	353	Missense	proximal	1	no	10.872	3.896	EPSD	COSMIC	9.540	Loss
Atypical_PIKK_ATM_ATM_ST	O95071	UBR5	Q13315	ATM	S598	K599Q	599	Missense	proximal	1	no	6.806	13.655	EPSD	COSMIC	9.540	Gain
Atypical_PIKK_ATM_ATM_ST	O95071	UBR5	Q13315	ATM	S612	C617R	617	Missense	distal	5	no	10.640	10.579	EPSD	COSMIC	9.540	Down-regulation
Atypical_PIKK_ATM_ATM_ST	O95071	UBR5	Q13315	ATM	S612	T616M	616	Missense	distal	4	no	10.640	10.813	EPSD	COSMIC	9.540	Up-regulation
Atypical_PIKK_ATM_ATM_ST	O95071	UBR5	Q13315	ATM	S612	P610L	610	Missense	proximal	-2	no	10.640	10.487	EPSD	COSMIC	9.540	Down-regulation
Atypical_PIKK_ATM_ATM_ST	O95071	UBR5	Q13315	ATM	S612	D619Y	619	Missense	distal	7	no	10.640	10.665	EPSD	COSMIC	9.540	Up-regulation
Atypical_PIKK_ATM_ATM_ST	O95071	UBR5	Q13315	ATM	S612	P613T	613	Missense	proximal	1	no	10.640	5.633	EPSD	COSMIC	9.540	Loss
Atypical_PIKK_ATM_ATM_ST	O95071	UBR5	Q13315	ATM	S612	P611Q	611	Missense	proximal	-1	no	10.640	10.865	EPSD	COSMIC	9.540	Up-regulation
Atypical_PIKK_ATM_ATM_ST	O95071	UBR5	Q13315	ATM	S1018	A1022T	1022	Missense	distal	4	no	9.895	10.330	EPSD	COSMIC	9.540	Up-regulation
Atypical_PIKK_ATM_ATM_ST	O95071	UBR5	Q13315	ATM	S1018	P1019S	1019	Missense	proximal	1	no	9.895	2.920	EPSD	COSMIC	9.540	Loss
Atypical_PIKK_ATM_ATM_ST	O95071	UBR5	Q13315	ATM	S1018	P1019T	1019	Missense	proximal	1	no	9.895	4.888	EPSD	COSMIC	9.540	Loss
Atypical_PIKK_ATM_ATM_ST	O95071	UBR5	Q13315	ATM	S1018	P1024S	1024	Missense	distal	6	no	9.895	9.906	EPSD	COSMIC;GDSC;CCLE	9.540	Up-regulation
Atypical_PIKK_ATM_ATM_ST	O95071	UBR5	Q13315	ATM	S1018	A1022G	1022	Missense	distal	4	no	9.895	10.371	EPSD	COSMIC	9.540	Up-regulation
Atypical_PIKK_ATM_ATM_ST	O95071	UBR5	Q13315	ATM	S1018	H1013P	1013	Missense	distal	-5	no	9.895	9.850	EPSD	COSMIC	9.540	Down-regulation
Atypical_PIKK_ATM_ATM_ST	O95071	UBR5	Q13315	ATM	S1308	P1309L	1309	Missense	proximal	1	no	11.601	10.047	EPSD	COSMIC	9.540	Down-regulation
Atypical_PIKK_ATM_ATM_ST	O95071	UBR5	Q13315	ATM	S1308	R1302H	1302	Missense	distal	-6	no	11.601	11.602	EPSD	COSMIC	9.540	Up-regulation
Atypical_PIKK_ATM_ATM_ST	O95071	UBR5	Q13315	ATM	S1308	R1304Q	1304	Missense	distal	-4	no	11.601	11.967	EPSD	COSMIC	9.540	Up-regulation
Atypical_PIKK_ATM_ATM_ST	O95071	UBR5	Q13315	ATM	S1308	P1315T	1315	Missense	distal	7	no	11.601	11.599	EPSD	COSMIC	9.540	Down-regulation
Atypical_PIKK_ATM_ATM_ST	O95071	UBR5	Q13315	ATM	S1347	S1341L	1341	Missense	distal	-6	no	13.700	13.411	EPSD	COSMIC	9.540	Down-regulation
Atypical_PIKK_ATM_ATM_ST	O95071	UBR5	Q13315	ATM	S1549	R1547L	1547	Missense	proximal	-2	no	16.098	16.151	EPSD	COSMIC	9.540	Up-regulation
Atypical_PIKK_ATM_ATM_ST	O95071	UBR5	Q13315	ATM	S1549	Q1550K	1550	Missense	proximal	1	no	16.098	9.250	EPSD	COSMIC	9.540	Loss
Atypical_PIKK_ATM_ATM_ST	O95071	UBR5	Q13315	ATM	S1549	R1555Q	1555	Missense	distal	6	no	16.098	16.094	EPSD	COSMIC	9.540	Down-regulation
Atypical_PIKK_ATM_ATM_ST	O95071	UBR5	Q13315	ATM	S1551	R1547L	1547	Missense	distal	-4	no	14.645	14.516	EPSD	COSMIC	9.540	Down-regulation
Atypical_PIKK_ATM_ATM_ST	O95071	UBR5	Q13315	ATM	S1551	Q1550K	1550	Missense	proximal	-1	no	14.645	14.520	EPSD	COSMIC	9.540	Down-regulation
Atypical_PIKK_ATM_ATM_ST	O95071	UBR5	Q13315	ATM	S1551	R1555Q	1555	Missense	distal	4	no	14.645	14.497	EPSD	COSMIC	9.540	Down-regulation
Atypical_PIKK_ATM_ATM_ST	O95071	UBR5	Q13315	ATM	S1610	M1612T	1612	Missense	proximal	2	no	9.419	10.213	EPSD	COSMIC	9.540	Gain
Atypical_PIKK_ATM_ATM_ST	O95071	UBR5	Q13315	ATM	S1679	S1681C	1681	Missense	proximal	2	no	16.287	15.034	EPSD;PhosphoSitePlus	COSMIC	9.540	Down-regulation
Atypical_PIKK_ATM_ATM_ST	O95071	UBR5	Q13315	ATM	S1875	A1879V	1879	Missense	distal	4	no	12.796	13.449	EPSD	COSMIC	9.540	Up-regulation
Atypical_PIKK_ATM_ATM_ST	O95071	UBR5	Q13315	ATM	S1875	A1879T	1879	Missense	distal	4	no	12.796	13.231	EPSD	COSMIC	9.540	Up-regulation
Atypical_PIKK_ATM_ATM_ST	O95071	UBR5	Q13315	ATM	S1875	Q1876H	1876	Missense	proximal	1	no	12.796	-2.112	EPSD	COSMIC	9.540	Loss
Atypical_PIKK_ATM_ATM_ST	O95071	UBR5	Q13315	ATM	S1875	N1869Y	1869	Missense	distal	-6	no	12.796	12.663	EPSD	COSMIC	9.540	Down-regulation
Atypical_PIKK_ATM_ATM_ST	O95071	UBR5	Q13315	ATM	S1875	N1877Y	1877	Missense	proximal	2	no	12.796	12.577	EPSD	COSMIC	9.540	Down-regulation
Atypical_PIKK_ATM_ATM_ST	O95071	UBR5	Q13315	ATM	T1977	R1978Q	1978	Missense	proximal	1	no	9.080	15.731	EPSD	COSMIC	9.540	Gain
Atypical_PIKK_ATM_ATM_ST	O95071	UBR5	Q13315	ATM	S2071	L2066I	2066	Missense	distal	-5	no	13.083	13.175	EPSD	COSMIC;GDSC;CCLE	9.540	Up-regulation
Atypical_PIKK_ATM_ATM_ST	O95071	UBR5	Q13315	ATM	S2071	L2074H	2074	Missense	distal	3	no	13.083	13.024	EPSD	COSMIC	9.540	Down-regulation
Atypical_PIKK_ATM_ATM_ST	O95071	UBR5	Q13315	ATM	S2071	E2064K	2064	Missense	distal	-7	no	13.083	12.415	EPSD	COSMIC	9.540	Down-regulation
Atypical_PIKK_ATM_ATM_ST	O95071	UBR5	Q13315	ATM	S2071	S2071I	2071	Missense	central	0	yes	13.083	0.000	EPSD	COSMIC	9.540	Loss
Atypical_PIKK_ATM_ATM_ST	O95071	UBR5	Q13315	ATM	S2241	V2244A	2244	Missense	distal	3	no	11.674	11.386	EPSD	COSMIC	9.540	Down-regulation
Atypical_PIKK_ATM_ATM_ST	O95071	UBR5	Q13315	ATM	S2241	R2248Q	2248	Missense	distal	7	no	11.674	11.649	EPSD	COSMIC	9.540	Down-regulation
Atypical_PIKK_ATM_ATM_ST	O95071	UBR5	Q13315	ATM	S2241	R2246Q	2246	Missense	distal	5	no	11.674	11.562	EPSD	COSMIC	9.540	Down-regulation
Atypical_PIKK_ATM_ATM_ST	O95071	UBR5	Q13315	ATM	S2384	P2387A	2387	Missense	distal	3	no	11.328	11.232	EPSD	COSMIC	9.540	Down-regulation
Atypical_PIKK_ATM_ATM_ST	O95071	UBR5	Q13315	ATM	S2586	R2580W	2580	Missense	distal	-6	no	14.138	13.970	EPSD;PhosphoSitePlus	COSMIC	9.540	Down-regulation
Atypical_PIKK_ATM_ATM_ST	O95071	UBR5	Q13315	ATM	S2586	A2585V	2585	Missense	proximal	-1	no	14.138	13.875	EPSD;PhosphoSitePlus	COSMIC	9.540	Down-regulation
Atypical_PIKK_ATM_ATM_ST	O95071	UBR5	Q13315	ATM	S2586	S2588A	2588	Missense	proximal	2	no	14.138	13.555	EPSD;PhosphoSitePlus	COSMIC	9.540	Down-regulation
Atypical_PIKK_ATM_ATM_ST	Q92945	KHSRP	Q13315	ATM	S181	D183V	183	Missense	proximal	2	no	10.909	9.637	EPSD	COSMIC	9.540	Down-regulation
Atypical_PIKK_ATM_ATM_ST	Q92945	KHSRP	Q13315	ATM	S181	G185A	185	Missense	distal	4	no	10.909	10.432	EPSD	COSMIC	9.540	Down-regulation
Atypical_PIKK_ATM_ATM_ST	Q92945	KHSRP	Q13315	ATM	S274	I268M	268	Missense	distal	-6	no	14.251	14.407	EPSD;PhosphoSitePlus	COSMIC;GDSC;CCLE	9.540	Up-regulation
Atypical_PIKK_ATM_ATM_ST	Q92945	KHSRP	Q13315	ATM	S670	G663D	663	Missense	distal	-7	no	15.038	15.328	PhosphoSitePlus;EPSD	COSMIC	9.540	Up-regulation
Atypical_PIKK_ATM_ATM_ST	Q96S59	RANBP9	Q13315	ATM	S181	I178V	178	Missense	distal	-3	no	13.194	12.942	EPSD;PhosphoSitePlus	COSMIC	9.540	Down-regulation
Atypical_PIKK_ATM_ATM_ST	Q96S59	RANBP9	Q13315	ATM	S613	R619K	619	Missense	distal	6	no	12.326	12.323	EPSD	COSMIC	9.540	Down-regulation
Atypical_PIKK_ATM_ATM_ST	Q92547	TOPBP1	Q13315	ATM	S747	S747N	747	Missense	central	0	yes	11.372	0.000	EPSD	COSMIC	9.540	Loss
Atypical_PIKK_ATM_ATM_ST	Q92547	TOPBP1	Q13315	ATM	S747	E744I	744	Missense	distal	-3	no	11.372	12.201	EPSD	COSMIC	9.540	Up-regulation
Atypical_PIKK_ATM_ATM_ST	Q92547	TOPBP1	Q13315	ATM	S805	R800T	800	Missense	distal	-5	no	11.277	11.113	EPSD	COSMIC	9.540	Down-regulation
Atypical_PIKK_ATM_ATM_ST	Q92547	TOPBP1	Q13315	ATM	S817	Q813E	813	Missense	distal	-4	no	9.377	10.100	EPSD	COSMIC	9.540	Gain
Atypical_PIKK_ATM_ATM_ST	Q92547	TOPBP1	Q13315	ATM	S853	R857M	857	Missense	distal	4	no	14.550	14.628	EPSD;PhosphoSitePlus	COSMIC	9.540	Up-regulation
Atypical_PIKK_ATM_ATM_ST	Q92547	TOPBP1	Q13315	ATM	S853	S853N	853	Missense	central	0	yes	14.550	0.000	EPSD;PhosphoSitePlus	COSMIC	9.540	Loss
Atypical_PIKK_ATM_ATM_ST	Q92547	TOPBP1	Q13315	ATM	S864	R857M	857	Missense	distal	-7	no	9.733	9.657	EPSD	COSMIC	9.540	Down-regulation
Atypical_PIKK_ATM_ATM_ST	Q92547	TOPBP1	Q13315	ATM	S864	V866G	866	Missense	proximal	2	no	9.733	9.767	EPSD	COSMIC	9.540	Up-regulation
Atypical_PIKK_ATM_ATM_ST	Q92547	TOPBP1	Q13315	ATM	S1002	R1008G	1008	Missense	distal	6	no	9.626	9.625	EPSD	COSMIC	9.540	Down-regulation
Atypical_PIKK_ATM_ATM_ST	Q92547	TOPBP1	Q13315	ATM	T1135	E1136Q	1136	Missense	proximal	1	no	5.959	11.856	EPSD	COSMIC	9.540	Gain
Atypical_PIKK_ATM_ATM_ST	Q92547	TOPBP1	Q13315	ATM	S1138	E1141A	1141	Missense	distal	3	no	13.698	13.929	EPSD;PhosphoSitePlus	COSMIC	9.540	Up-regulation
Atypical_PIKK_ATM_ATM_ST	Q92547	TOPBP1	Q13315	ATM	S1138	W1145L	1145	Missense	distal	7	no	13.698	13.656	EPSD;PhosphoSitePlus	COSMIC	9.540	Down-regulation
Atypical_PIKK_ATM_ATM_ST	Q92547	TOPBP1	Q13315	ATM	S1138	E1136Q	1136	Missense	proximal	-2	no	13.698	13.393	EPSD;PhosphoSitePlus	COSMIC	9.540	Down-regulation
Atypical_PIKK_ATM_ATM_ST	Q92547	TOPBP1	Q13315	ATM	S1138	E1136A	1136	Missense	proximal	-2	no	13.698	13.329	EPSD;PhosphoSitePlus	COSMIC	9.540	Down-regulation
Atypical_PIKK_ATM_ATM_ST	Q92547	TOPBP1	Q13315	ATM	S1504	P1510S	1510	Missense	distal	6	no	14.251	14.262	EPSD	COSMIC	9.540	Up-regulation
Atypical_PIKK_ATM_ATM_ST	O94916	NFAT5	Q13315	ATM	S155	R156Q	156	Missense	proximal	1	no	7.262	13.913	EPSD	COSMIC	9.540	Gain
Atypical_PIKK_ATM_ATM_ST	O94916	NFAT5	Q13315	ATM	S238	S238C	238	Missense	central	0	yes	12.123	0.000	EPSD	COSMIC	9.540	Loss
Atypical_PIKK_ATM_ATM_ST	O94916	NFAT5	Q13315	ATM	S238	H234R	234	Missense	distal	-4	no	12.123	11.992	EPSD	COSMIC	9.540	Down-regulation
Atypical_PIKK_ATM_ATM_ST	O94916	NFAT5	Q13315	ATM	S238	Q239E	239	Missense	proximal	1	no	12.123	6.226	EPSD	COSMIC	9.540	Loss
Atypical_PIKK_ATM_ATM_ST	O94916	NFAT5	Q13315	ATM	S238	H234P	234	Missense	distal	-4	no	12.123	12.133	EPSD	COSMIC	9.540	Up-regulation
Atypical_PIKK_ATM_ATM_ST	O94916	NFAT5	Q13315	ATM	S238	K245I	245	Missense	distal	7	no	12.123	12.131	EPSD	COSMIC	9.540	Up-regulation
Atypical_PIKK_ATM_ATM_ST	O94916	NFAT5	Q13315	ATM	T439	V444G	444	Missense	distal	5	no	13.708	13.674	EPSD	COSMIC	9.540	Down-regulation
Atypical_PIKK_ATM_ATM_ST	O94916	NFAT5	Q13315	ATM	T439	E446D	446	Missense	distal	7	no	13.708	13.720	EPSD	COSMIC	9.540	Up-regulation
Atypical_PIKK_ATM_ATM_ST	O94916	NFAT5	Q13315	ATM	T631	E636Q	636	Missense	distal	5	no	14.850	15.074	EPSD	COSMIC	9.540	Up-regulation
Atypical_PIKK_ATM_ATM_ST	O94916	NFAT5	Q13315	ATM	T631	V628I	628	Missense	distal	-3	no	14.850	15.101	EPSD	COSMIC	9.540	Up-regulation
Atypical_PIKK_ATM_ATM_ST	O94916	NFAT5	Q13315	ATM	T631	S630T	630	Missense	proximal	-1	no	14.850	14.860	EPSD	COSMIC	9.540	Up-regulation
Atypical_PIKK_ATM_ATM_ST	O94916	NFAT5	Q13315	ATM	T680	Q681H	681	Missense	proximal	1	no	14.558	-0.351	EPSD	COSMIC	9.540	Loss
Atypical_PIKK_ATM_ATM_ST	O94916	NFAT5	Q13315	ATM	T680	I678V	678	Missense	proximal	-2	no	14.558	14.583	EPSD	COSMIC	9.540	Up-regulation
Atypical_PIKK_ATM_ATM_ST	O94916	NFAT5	Q13315	ATM	T680	G687V	687	Missense	distal	7	no	14.558	14.565	EPSD	COSMIC	9.540	Up-regulation
Atypical_PIKK_ATM_ATM_ST	O94916	NFAT5	Q13315	ATM	T680	S684L	684	Missense	distal	4	no	14.558	14.899	EPSD	COSMIC	9.540	Up-regulation
Atypical_PIKK_ATM_ATM_ST	O94916	NFAT5	Q13315	ATM	S684	Q681H	681	Missense	distal	-3	no	13.837	13.967	EPSD	COSMIC	9.540	Up-regulation
Atypical_PIKK_ATM_ATM_ST	O94916	NFAT5	Q13315	ATM	S684	P690L	690	Missense	distal	6	no	13.837	13.792	EPSD	COSMIC	9.540	Down-regulation
Atypical_PIKK_ATM_ATM_ST	O94916	NFAT5	Q13315	ATM	S684	I678V	678	Missense	distal	-6	no	13.837	13.981	EPSD	COSMIC	9.540	Up-regulation
Atypical_PIKK_ATM_ATM_ST	O94916	NFAT5	Q13315	ATM	S684	G687V	687	Missense	distal	3	no	13.837	14.050	EPSD	COSMIC	9.540	Up-regulation
Atypical_PIKK_ATM_ATM_ST	O94916	NFAT5	Q13315	ATM	S684	S684L	684	Missense	central	0	yes	13.837	0.000	EPSD	COSMIC	9.540	Loss
Atypical_PIKK_ATM_ATM_ST	O94916	NFAT5	Q13315	ATM	S1197	P1194A	1194	Missense	distal	-3	no	14.968	14.326	PhosphoSitePlus;EPSD	COSMIC	9.540	Down-regulation
Atypical_PIKK_ATM_ATM_ST	O94916	NFAT5	Q13315	ATM	S1197	P1204S	1204	Missense	distal	7	no	14.968	14.949	PhosphoSitePlus;EPSD	COSMIC	9.540	Down-regulation
Atypical_PIKK_ATM_ATM_ST	O94916	NFAT5	Q13315	ATM	S1247	Q1252E	1252	Missense	distal	5	no	14.424	14.200	EPSD;PhosphoSitePlus	COSMIC	9.540	Down-regulation
Atypical_PIKK_ATM_ATM_ST	O94916	NFAT5	Q13315	ATM	S1247	Q1242E	1242	Missense	distal	-5	no	14.424	14.392	EPSD;PhosphoSitePlus	COSMIC	9.540	Down-regulation
Atypical_PIKK_ATM_ATM_ST	O94916	NFAT5	Q13315	ATM	S1247	N1244D	1244	Missense	distal	-3	no	14.424	14.697	EPSD;PhosphoSitePlus	COSMIC	9.540	Up-regulation
Atypical_PIKK_ATM_ATM_ST	O94916	NFAT5	Q13315	ATM	S1247	P1246L	1246	Missense	proximal	-1	no	14.424	14.581	EPSD;PhosphoSitePlus	COSMIC	9.540	Up-regulation
Atypical_PIKK_ATM_ATM_ST	O94916	NFAT5	Q13315	ATM	S1247	P1246Q	1246	Missense	proximal	-1	no	14.424	14.649	EPSD;PhosphoSitePlus	COSMIC	9.540	Up-regulation
Atypical_PIKK_ATM_ATM_ST	O94916	NFAT5	Q13315	ATM	S1247	N1244Y	1244	Missense	distal	-3	no	14.424	14.583	EPSD;PhosphoSitePlus	COSMIC	9.540	Up-regulation
Atypical_PIKK_ATM_ATM_ST	O94916	NFAT5	Q13315	ATM	S1247	S1247Y	1247	Missense	central	0	yes	14.424	0.000	EPSD;PhosphoSitePlus	COSMIC	9.540	Loss
Atypical_PIKK_ATM_ATM_ST	O94916	NFAT5	Q13315	ATM	S1367	S1366R	1366	Missense	proximal	-1	no	14.420	14.046	EPSD;PhosphoSitePlus	COSMIC	9.540	Down-regulation
Atypical_PIKK_ATM_ATM_ST	O94916	NFAT5	Q13315	ATM	S1367	G1363W	1363	Missense	distal	-4	no	14.420	13.923	EPSD;PhosphoSitePlus	COSMIC;CCLE	9.540	Down-regulation
Atypical_PIKK_ATM_ATM_ST	O94916	NFAT5	Q13315	ATM	S1367	V1372I	1372	Missense	distal	5	no	14.420	14.418	EPSD;PhosphoSitePlus	COSMIC	9.540	Down-regulation
Atypical_PIKK_ATM_ATM_ST	P12956	XRCC6	Q13315	ATM	S27	D29N	29	Missense	proximal	2	no	12.375	11.354	PhosphoSitePlus;EPSD	COSMIC	9.540	Down-regulation
Atypical_PIKK_ATM_ATM_ST	P12956	XRCC6	Q13315	ATM	S27	G28E	28	Missense	proximal	1	no	12.375	12.953	PhosphoSitePlus;EPSD	COSMIC;GDSC	9.540	Up-regulation
Atypical_PIKK_ATM_ATM_ST	P12956	XRCC6	Q13315	ATM	S33	D29N	29	Missense	distal	-4	no	12.467	11.543	EPSD;PhosphoSitePlus	COSMIC	9.540	Down-regulation
Atypical_PIKK_ATM_ATM_ST	P12956	XRCC6	Q13315	ATM	S33	G28E	28	Missense	distal	-5	no	12.467	12.248	EPSD;PhosphoSitePlus	COSMIC;GDSC	9.540	Down-regulation
Atypical_PIKK_ATM_ATM_ST	P12956	XRCC6	Q13315	ATM	S51	M48V	48	Missense	distal	-3	no	15.886	15.950	EPSD	COSMIC	9.540	Up-regulation
Atypical_PIKK_ATM_ATM_ST	P12956	XRCC6	Q13315	ATM	S319	R325C	325	Missense	distal	6	no	12.037	11.982	EPSD	COSMIC;GDSC;CCLE	9.540	Down-regulation
Atypical_PIKK_ATM_ATM_ST	P12956	XRCC6	Q13315	ATM	S319	L312M	312	Missense	distal	-7	no	12.037	12.149	EPSD	COSMIC	9.540	Up-regulation
Atypical_PIKK_ATM_ATM_ST	P12956	XRCC6	Q13315	ATM	T334	I328V	328	Missense	distal	-6	no	9.965	10.110	EPSD	COSMIC	9.540	Up-regulation
Atypical_PIKK_ATM_ATM_ST	P12956	XRCC6	Q13315	ATM	T334	F340L	340	Missense	distal	6	no	9.965	9.985	EPSD	COSMIC	9.540	Up-regulation
Atypical_PIKK_ATM_ATM_ST	P12956	XRCC6	Q13315	ATM	T334	E330K	330	Missense	distal	-4	no	9.965	8.994	EPSD	COSMIC	9.540	Loss
Atypical_PIKK_ATM_ATM_ST	P12956	XRCC6	Q13315	ATM	T334	R339Q	339	Missense	distal	5	no	9.965	9.854	EPSD	COSMIC;CCLE	9.540	Down-regulation
Atypical_PIKK_ATM_ATM_ST	P12956	XRCC6	Q13315	ATM	T507	P500L	500	Missense	distal	-7	no	10.243	9.891	EPSD	COSMIC	9.540	Down-regulation
Atypical_PIKK_ATM_ATM_ST	P12956	XRCC6	Q13315	ATM	T507	V511A	511	Missense	distal	4	no	10.243	9.590	EPSD	COSMIC	9.540	Down-regulation
Atypical_PIKK_ATM_ATM_ST	P12956	XRCC6	Q13315	ATM	T507	P509S	509	Missense	proximal	2	no	10.243	10.697	EPSD	COSMIC	9.540	Up-regulation
Atypical_PIKK_ATM_ATM_ST	P12956	XRCC6	Q13315	ATM	T507	D505N	505	Missense	proximal	-2	no	10.243	10.361	EPSD	COSMIC	9.540	Up-regulation
Atypical_PIKK_ATM_ATM_ST	P12956	XRCC6	Q13315	ATM	S550	R554W	554	Missense	distal	4	no	9.837	9.982	EPSD	COSMIC	9.540	Up-regulation
Atypical_PIKK_ATM_ATM_ST	P12956	XRCC6	Q13315	ATM	S550	D546N	546	Missense	distal	-4	no	9.837	8.913	EPSD	COSMIC	9.540	Loss
Atypical_PIKK_ATM_ATM_ST	P12956	XRCC6	Q13315	ATM	S550	R543K	543	Missense	distal	-7	no	9.837	9.923	EPSD	COSMIC	9.540	Up-regulation
Atypical_PIKK_ATM_ATM_ST	P12956	XRCC6	Q13315	ATM	S560	R554W	554	Missense	distal	-6	no	11.355	11.187	EPSD	COSMIC	9.540	Down-regulation
Atypical_PIKK_ATM_ATM_ST	Q96SD1	DCLRE1C	Q13315	ATM	S72	R76I	76	Missense	distal	4	no	9.184	9.665	EPSD	COSMIC	9.540	Gain
Atypical_PIKK_ATM_ATM_ST	Q96SD1	DCLRE1C	Q13315	ATM	T251	H254Y	254	Missense	distal	3	no	11.244	11.263	EPSD	COSMIC	9.540	Up-regulation
Atypical_PIKK_ATM_ATM_ST	Q96SD1	DCLRE1C	Q13315	ATM	S503	S510R	510	Missense	distal	7	no	12.034	12.069	PhosphoSitePlus;EPSD	COSMIC	9.540	Up-regulation
Atypical_PIKK_ATM_ATM_ST	Q96SD1	DCLRE1C	Q13315	ATM	S503	E498D	498	Missense	distal	-5	no	12.034	11.988	PhosphoSitePlus;EPSD	COSMIC;GDSC;CCLE	9.540	Down-regulation
Atypical_PIKK_ATM_ATM_ST	Q96SD1	DCLRE1C	Q13315	ATM	S503	N506D	506	Missense	distal	3	no	12.034	12.017	PhosphoSitePlus;EPSD	COSMIC	9.540	Down-regulation
Atypical_PIKK_ATM_ATM_ST	Q96SD1	DCLRE1C	Q13315	ATM	S503	F507V	507	Missense	distal	4	no	12.034	11.512	PhosphoSitePlus;EPSD	COSMIC;CCLE	9.540	Down-regulation
Atypical_PIKK_ATM_ATM_ST	Q96SD1	DCLRE1C	Q13315	ATM	S516	S510R	510	Missense	distal	-6	no	18.674	18.494	EPSD;PhosphoSitePlus	COSMIC	9.540	Down-regulation
Atypical_PIKK_ATM_ATM_ST	Q96SD1	DCLRE1C	Q13315	ATM	S516	S518L	518	Missense	proximal	2	no	18.674	17.430	EPSD;PhosphoSitePlus	COSMIC	9.540	Down-regulation
Atypical_PIKK_ATM_ATM_ST	Q96SD1	DCLRE1C	Q13315	ATM	S518	S518L	518	Missense	central	0	yes	12.901	0.000	EPSD	COSMIC	9.540	Loss
Atypical_PIKK_ATM_ATM_ST	Q96SD1	DCLRE1C	Q13315	ATM	S518	S525F	525	Missense	distal	7	no	12.901	12.961	EPSD	COSMIC	9.540	Up-regulation
Atypical_PIKK_ATM_ATM_ST	Q96SD1	DCLRE1C	Q13315	ATM	S534	S534F	534	Missense	central	0	yes	15.088	0.000	EPSD	COSMIC	9.540	Loss
Atypical_PIKK_ATM_ATM_ST	Q96SD1	DCLRE1C	Q13315	ATM	S538	E545D	545	Missense	distal	7	no	13.667	13.679	EPSD	COSMIC	9.540	Up-regulation
Atypical_PIKK_ATM_ATM_ST	Q96SD1	DCLRE1C	Q13315	ATM	S538	S534F	534	Missense	distal	-4	no	13.667	12.268	EPSD	COSMIC	9.540	Down-regulation
Atypical_PIKK_ATM_ATM_ST	Q96SD1	DCLRE1C	Q13315	ATM	S548	E545D	545	Missense	distal	-3	no	12.812	13.218	EPSD	COSMIC	9.540	Up-regulation
Atypical_PIKK_ATM_ATM_ST	Q96SD1	DCLRE1C	Q13315	ATM	S553	D556H	556	Missense	distal	3	no	16.420	16.460	EPSD	COSMIC	9.540	Up-regulation
Atypical_PIKK_ATM_ATM_ST	Q96SD1	DCLRE1C	Q13315	ATM	S562	D569N	569	Missense	distal	7	no	15.649	15.656	EPSD	COSMIC	9.540	Up-regulation
Atypical_PIKK_ATM_ATM_ST	Q96SD1	DCLRE1C	Q13315	ATM	S562	N566H	566	Missense	distal	4	no	15.649	15.639	EPSD	COSMIC	9.540	Down-regulation
Atypical_PIKK_ATM_ATM_ST	Q96SD1	DCLRE1C	Q13315	ATM	S562	D556H	556	Missense	distal	-6	no	15.649	15.497	EPSD	COSMIC	9.540	Down-regulation
Atypical_PIKK_ATM_ATM_ST	Q96SD1	DCLRE1C	Q13315	ATM	S562	Q563H	563	Missense	proximal	1	no	15.649	0.740	EPSD	COSMIC	9.540	Loss
Atypical_PIKK_ATM_ATM_ST	Q96SD1	DCLRE1C	Q13315	ATM	S645	D650E	650	Missense	distal	5	no	13.341	13.083	EPSD;PhosphoSitePlus	COSMIC	9.540	Down-regulation
Atypical_PIKK_ATM_ATM_ST	Q96SD1	DCLRE1C	Q13315	ATM	S645	S647N	647	Missense	proximal	2	no	13.341	12.699	EPSD;PhosphoSitePlus	COSMIC	9.540	Down-regulation
Atypical_PIKK_ATM_ATM_ST	Q96SD1	DCLRE1C	Q13315	ATM	S645	L639F	639	Missense	distal	-6	no	13.341	13.098	EPSD;PhosphoSitePlus	COSMIC	9.540	Down-regulation
Atypical_PIKK_ATM_ATM_ST	Q96SD1	DCLRE1C	Q13315	ATM	S645	S645F	645	Missense	central	0	yes	13.341	0.000	EPSD;PhosphoSitePlus	COSMIC	9.540	Loss
Atypical_PIKK_ATM_ATM_ST	Q96SD1	DCLRE1C	Q13315	ATM	T656	D650E	650	Missense	distal	-6	no	9.967	10.181	EPSD;PhosphoSitePlus	COSMIC	9.540	Up-regulation
Atypical_PIKK_ATM_ATM_ST	Q7LG56	RRM2B	Q13315	ATM	S20	S25G	25	Missense	distal	5	no	9.872	10.050	EPSD	COSMIC	9.540	Up-regulation
Atypical_PIKK_ATM_ATM_ST	Q7LG56	RRM2B	Q13315	ATM	S25	K28N	28	Missense	distal	3	no	10.055	10.142	EPSD	COSMIC	9.540	Up-regulation
Atypical_PIKK_ATM_ATM_ST	Q7LG56	RRM2B	Q13315	ATM	S25	K28R	28	Missense	distal	3	no	10.055	10.127	EPSD	COSMIC	9.540	Up-regulation
Atypical_PIKK_ATM_ATM_ST	Q7LG56	RRM2B	Q13315	ATM	S25	S25G	25	Missense	central	0	yes	10.055	0.000	EPSD	COSMIC	9.540	Loss
Atypical_PIKK_ATM_ATM_ST	Q7LG56	RRM2B	Q13315	ATM	S72	A66S	66	Missense	distal	-6	no	12.087	12.108	PhosphoSitePlus	COSMIC	9.540	Up-regulation
Atypical_PIKK_ATM_ATM_ST	Q7LG56	RRM2B	Q13315	ATM	S72	A66T	66	Missense	distal	-6	no	12.087	12.038	PhosphoSitePlus	COSMIC	9.540	Down-regulation
Atypical_PIKK_ATM_ATM_ST	Q7LG56	RRM2B	Q13315	ATM	S72	W78F	78	Missense	distal	6	no	12.087	12.060	PhosphoSitePlus	COSMIC	9.540	Down-regulation
Atypical_PIKK_ATM_ATM_ST	Q7LG56	RRM2B	Q13315	ATM	S72	N79D	79	Missense	distal	7	no	12.087	12.080	PhosphoSitePlus	COSMIC	9.540	Down-regulation
Atypical_PIKK_ATM_ATM_ST	Q7LG56	RRM2B	Q13315	ATM	S329	E330K	330	Missense	proximal	1	no	11.121	10.169	EPSD	COSMIC	9.540	Down-regulation
Atypical_PIKK_ATM_ATM_ST	Q7LG56	RRM2B	Q13315	ATM	S329	R327P	327	Missense	proximal	-2	no	11.121	11.327	EPSD	COSMIC;GDSC;CCLE	9.540	Up-regulation
Atypical_PIKK_ATM_ATM_ST	Q7LG56	RRM2B	Q13315	ATM	S329	F323L	323	Missense	distal	-6	no	11.121	11.364	EPSD	COSMIC;GDSC;CCLE	9.540	Up-regulation
Atypical_PIKK_ATM_ATM_ST	Q7LG56	RRM2B	Q13315	ATM	S329	R333C	333	Missense	distal	4	no	11.121	11.448	EPSD	COSMIC	9.540	Up-regulation
Atypical_PIKK_ATM_ATM_ST	Q9H2K8	TAOK3	Q13315	ATM	S173	A175T	175	Missense	proximal	2	no	10.257	10.578	EPSD	COSMIC	9.540	Up-regulation
Atypical_PIKK_ATM_ATM_ST	Q9H2K8	TAOK3	Q13315	ATM	S173	G180D	180	Missense	distal	7	no	10.257	10.224	EPSD	COSMIC	9.540	Down-regulation
Atypical_PIKK_ATM_ATM_ST	Q9H2K8	TAOK3	Q13315	ATM	T419	P416S	416	Missense	distal	-3	no	14.813	14.617	EPSD	COSMIC	9.540	Down-regulation
Atypical_PIKK_ATM_ATM_ST	Q9H2K8	TAOK3	Q13315	ATM	T419	P416L	416	Missense	distal	-3	no	14.813	14.826	EPSD	COSMIC	9.540	Up-regulation
Atypical_PIKK_ATM_ATM_ST	Q9H2K8	TAOK3	Q13315	ATM	T419	P412H	412	Missense	distal	-7	no	14.813	14.736	EPSD	COSMIC	9.540	Down-regulation
Atypical_PIKK_ATM_ATM_ST	Q9H2K8	TAOK3	Q13315	ATM	T419	S424R	424	Missense	distal	5	no	14.813	14.978	EPSD	COSMIC	9.540	Up-regulation
Atypical_PIKK_ATM_ATM_ST	Q9H2K8	TAOK3	Q13315	ATM	S424	S424R	424	Missense	central	0	yes	13.670	0.000	EPSD	COSMIC	9.540	Loss
Atypical_PIKK_ATM_ATM_ST	Q9H2K8	TAOK3	Q13315	ATM	S551	E550K	550	Missense	proximal	-1	no	14.004	13.601	EPSD;PhosphoSitePlus	COSMIC	9.540	Down-regulation
Atypical_PIKK_ATM_ATM_ST	Q9H2K8	TAOK3	Q13315	ATM	S551	K557N	557	Missense	distal	6	no	14.004	14.014	EPSD;PhosphoSitePlus	COSMIC	9.540	Up-regulation
Atypical_PIKK_ATM_ATM_ST	Q9H2K8	TAOK3	Q13315	ATM	T573	E577K	577	Missense	distal	4	no	9.195	9.572	EPSD	COSMIC	9.540	Gain
Atypical_PIKK_ATM_ATM_ST	Q9H2K8	TAOK3	Q13315	ATM	S782	D788H	788	Missense	distal	6	no	14.981	14.969	EPSD	COSMIC	9.540	Down-regulation
Atypical_PIKK_ATM_ATM_ST	Q9H2K8	TAOK3	Q13315	ATM	S782	D788N	788	Missense	distal	6	no	14.981	14.992	EPSD	COSMIC	9.540	Up-regulation
Atypical_PIKK_ATM_ATM_ST	Q96RU2	USP28	Q13315	ATM	S67	R62H	62	Missense	distal	-5	no	13.532	13.504	EPSD;PhosphoSitePlus	COSMIC	9.540	Down-regulation
Atypical_PIKK_ATM_ATM_ST	Q96RU2	USP28	Q13315	ATM	S375	R369T	369	Missense	distal	-6	no	11.657	11.768	EPSD	COSMIC	9.540	Up-regulation
Atypical_PIKK_ATM_ATM_ST	Q96RU2	USP28	Q13315	ATM	S375	K381Q	381	Missense	distal	6	no	11.657	11.656	EPSD	COSMIC	9.540	Down-regulation
Atypical_PIKK_ATM_ATM_ST	Q96RU2	USP28	Q13315	ATM	S375	E371Q	371	Missense	distal	-4	no	11.657	10.934	EPSD	COSMIC	9.540	Down-regulation
Atypical_PIKK_ATM_ATM_ST	Q96RU2	USP28	Q13315	ATM	S375	R369K	369	Missense	distal	-6	no	11.657	11.724	EPSD	COSMIC	9.540	Up-regulation
Atypical_PIKK_ATM_ATM_ST	Q96RU2	USP28	Q13315	ATM	S375	E371K	371	Missense	distal	-4	no	11.657	10.685	EPSD	COSMIC	9.540	Down-regulation
Atypical_PIKK_ATM_ATM_ST	Q96RU2	USP28	Q13315	ATM	T491	Q496R	496	Missense	distal	5	no	9.882	9.994	EPSD	COSMIC	9.540	Up-regulation
Atypical_PIKK_ATM_ATM_ST	Q96RU2	USP28	Q13315	ATM	S495	S500F	500	Missense	distal	5	no	15.523	15.829	PhosphoSitePlus;EPSD	COSMIC	9.540	Up-regulation
Atypical_PIKK_ATM_ATM_ST	Q96RU2	USP28	Q13315	ATM	S495	Q496R	496	Missense	proximal	1	no	15.523	8.872	PhosphoSitePlus;EPSD	COSMIC	9.540	Loss
Atypical_PIKK_ATM_ATM_ST	Q96RU2	USP28	Q13315	ATM	S504	S500F	500	Missense	distal	-4	no	10.400	9.001	EPSD	COSMIC	9.540	Loss
Atypical_PIKK_ATM_ATM_ST	Q96RU2	USP28	Q13315	ATM	S714	D716G	716	Missense	proximal	2	no	16.349	15.111	EPSD;PhosphoSitePlus	COSMIC	9.540	Down-regulation
Atypical_PIKK_ATM_ATM_ST	Q96RU2	USP28	Q13315	ATM	S720	D716G	716	Missense	distal	-4	no	16.886	16.103	EPSD;PhosphoSitePlus	COSMIC	9.540	Down-regulation
Atypical_PIKK_ATM_ATM_ST	Q96RU2	USP28	Q13315	ATM	S720	S724L	724	Missense	distal	4	no	16.886	17.228	EPSD;PhosphoSitePlus	COSMIC	9.540	Up-regulation
Atypical_PIKK_ATM_ATM_ST	Q96RU2	USP28	Q13315	ATM	S720	S724P	724	Missense	distal	4	no	16.886	17.009	EPSD;PhosphoSitePlus	COSMIC	9.540	Up-regulation
Atypical_PIKK_ATM_ATM_ST	Q96RU2	USP28	Q13315	ATM	S794	D792N	792	Missense	proximal	-2	no	10.360	10.479	EPSD	COSMIC	9.540	Up-regulation
Atypical_PIKK_ATM_ATM_ST	Q96RU2	USP28	Q13315	ATM	S856	A851T	851	Missense	distal	-5	no	11.522	11.441	EPSD	COSMIC;GDSC	9.540	Down-regulation
Atypical_PIKK_ATM_ATM_ST	Q96RU2	USP28	Q13315	ATM	S856	I862V	862	Missense	distal	6	no	11.522	11.538	EPSD	COSMIC	9.540	Up-regulation
Atypical_PIKK_ATM_ATM_ST	Q96RU2	USP28	Q13315	ATM	S1037	P1036L	1036	Missense	proximal	-1	no	9.409	9.566	EPSD	COSMIC	9.540	Gain
Atypical_PIKK_ATM_ATM_ST	Q96RU2	USP28	Q13315	ATM	S1053	P1046S	1046	Missense	distal	-7	no	9.924	10.160	EPSD	COSMIC	9.540	Up-regulation
Atypical_PIKK_ATM_ATM_ST	Q96RU2	USP28	Q13315	ATM	S1053	L1057P	1057	Missense	distal	4	no	9.924	9.705	EPSD	COSMIC	9.540	Down-regulation
Atypical_PIKK_ATM_ATM_ST	Q96RU2	USP28	Q13315	ATM	S1053	N1052D	1052	Missense	proximal	-1	no	9.924	9.925	EPSD	COSMIC	9.540	Up-regulation
Atypical_PIKK_ATM_ATM_ST	Q96RU2	USP28	Q13315	ATM	S1053	N1052S	1052	Missense	proximal	-1	no	9.924	9.979	EPSD	COSMIC	9.540	Up-regulation
Atypical_PIKK_ATM_ATM_ST	Q5TZA2	CROCC	Q13315	ATM	S471	G472S	472	Missense	proximal	1	no	9.820	4.517	EPSD	COSMIC;CCLE	9.540	Loss
Atypical_PIKK_ATM_ATM_ST	Q5TZA2	CROCC	Q13315	ATM	S471	V468I	468	Missense	distal	-3	no	9.820	10.072	EPSD	COSMIC;GDSC;CCLE	9.540	Up-regulation
Atypical_PIKK_ATM_ATM_ST	Q5TZA2	CROCC	Q13315	ATM	S494	P493L	493	Missense	proximal	-1	no	10.426	10.583	EPSD	COSMIC	9.540	Up-regulation
Atypical_PIKK_ATM_ATM_ST	Q5TZA2	CROCC	Q13315	ATM	S494	R491Q	491	Missense	distal	-3	no	10.426	9.651	EPSD	COSMIC	9.540	Down-regulation
Atypical_PIKK_ATM_ATM_ST	Q5TZA2	CROCC	Q13315	ATM	S494	P493S	493	Missense	proximal	-1	no	10.426	10.718	EPSD	COSMIC	9.540	Up-regulation
Atypical_PIKK_ATM_ATM_ST	Q5TZA2	CROCC	Q13315	ATM	S506	P513L	513	Missense	distal	7	no	10.429	10.430	EPSD	COSMIC	9.540	Up-regulation
Atypical_PIKK_ATM_ATM_ST	Q5TZA2	CROCC	Q13315	ATM	S512	P513L	513	Missense	proximal	1	no	10.006	8.451	EPSD	COSMIC	9.540	Loss
Atypical_PIKK_ATM_ATM_ST	Q5TZA2	CROCC	Q13315	ATM	S512	A514V	514	Missense	proximal	2	no	10.006	9.697	EPSD	COSMIC	9.540	Down-regulation
Atypical_PIKK_ATM_ATM_ST	Q5TZA2	CROCC	Q13315	ATM	S737	D736N	736	Missense	proximal	-1	no	11.065	11.064	EPSD	COSMIC	9.540	Down-regulation
Atypical_PIKK_ATM_ATM_ST	Q5TZA2	CROCC	Q13315	ATM	S737	Q735K	735	Missense	proximal	-2	no	11.065	10.794	EPSD	COSMIC	9.540	Down-regulation
Atypical_PIKK_ATM_ATM_ST	Q5TZA2	CROCC	Q13315	ATM	S737	S733F	733	Missense	distal	-4	no	11.065	9.666	EPSD	COSMIC	9.540	Down-regulation
Atypical_PIKK_ATM_ATM_ST	Q5TZA2	CROCC	Q13315	ATM	S830	T824M	824	Missense	distal	-6	no	13.449	13.273	EPSD	COSMIC	9.540	Down-regulation
Atypical_PIKK_ATM_ATM_ST	Q5TZA2	CROCC	Q13315	ATM	T958	D965H	965	Missense	distal	7	no	13.100	13.120	EPSD	COSMIC	9.540	Up-regulation
Atypical_PIKK_ATM_ATM_ST	Q5TZA2	CROCC	Q13315	ATM	S1460	D1464E	1464	Missense	distal	4	no	9.587	9.082	EPSD	COSMIC	9.540	Loss
Atypical_PIKK_ATM_ATM_ST	Q5TZA2	CROCC	Q13315	ATM	S1476	S1476N	1476	Missense	central	0	yes	10.834	0.000	EPSD	COSMIC	9.540	Loss
Atypical_PIKK_ATM_ATM_ST	Q5TZA2	CROCC	Q13315	ATM	S1476	P1477S	1477	Missense	proximal	1	no	10.834	3.859	EPSD	COSMIC	9.540	Loss
Atypical_PIKK_ATM_ATM_ST	Q5TZA2	CROCC	Q13315	ATM	S1476	T1479I	1479	Missense	distal	3	no	10.834	11.255	EPSD	COSMIC	9.540	Up-regulation
Atypical_PIKK_ATM_ATM_ST	Q5TZA2	CROCC	Q13315	ATM	S1476	G1473R	1473	Missense	distal	-3	no	10.834	11.296	EPSD	COSMIC	9.540	Up-regulation
Atypical_PIKK_ATM_ATM_ST	Q5TZA2	CROCC	Q13315	ATM	S1483	S1476N	1476	Missense	distal	-7	no	9.755	9.568	EPSD	COSMIC	9.540	Down-regulation
Atypical_PIKK_ATM_ATM_ST	Q5TZA2	CROCC	Q13315	ATM	S1483	P1477S	1477	Missense	distal	-6	no	9.755	9.814	EPSD	COSMIC	9.540	Up-regulation
Atypical_PIKK_ATM_ATM_ST	Q5TZA2	CROCC	Q13315	ATM	S1483	T1479I	1479	Missense	distal	-4	no	9.755	9.426	EPSD	COSMIC	9.540	Loss
Atypical_PIKK_ATM_ATM_ST	Q5TZA2	CROCC	Q13315	ATM	S1486	T1479I	1479	Missense	distal	-7	no	13.105	12.522	EPSD	COSMIC	9.540	Down-regulation
Atypical_PIKK_ATM_ATM_ST	Q5TZA2	CROCC	Q13315	ATM	S1499	A1498T	1498	Missense	proximal	-1	no	10.289	10.460	EPSD	COSMIC	9.540	Up-regulation
Atypical_PIKK_ATM_ATM_ST	Q5TZA2	CROCC	Q13315	ATM	S2009	S2009C	2009	Missense	central	0	yes	9.589	0.000	EPSD	COSMIC;GDSC;CCLE	9.540	Loss
Atypical_PIKK_ATM_ATM_ST	Q5TZA2	CROCC	Q13315	ATM	S2009	P2010T	2010	Missense	proximal	1	no	9.589	4.582	EPSD	COSMIC	9.540	Loss
Atypical_PIKK_ATM_ATM_ST	Q96J02	ITCH	Q13315	ATM	S6	M11L	11	Missense	distal	5	no	12.929	12.909	EPSD	COSMIC	9.540	Down-regulation
Atypical_PIKK_ATM_ATM_ST	Q96J02	ITCH	Q13315	ATM	S6	S2F	2	Missense	distal	-4	no	12.929	11.531	EPSD	COSMIC	9.540	Down-regulation
Atypical_PIKK_ATM_ATM_ST	Q96J02	ITCH	Q13315	ATM	S18	M11L	11	Missense	distal	-7	no	14.695	14.582	EPSD	COSMIC	9.540	Down-regulation
Atypical_PIKK_ATM_ATM_ST	Q96J02	ITCH	Q13315	ATM	S18	M16I	16	Missense	proximal	-2	no	14.695	14.444	EPSD	COSMIC	9.540	Down-regulation
Atypical_PIKK_ATM_ATM_ST	Q96J02	ITCH	Q13315	ATM	S62	P63S	63	Missense	proximal	1	no	11.024	4.048	EPSD	COSMIC	9.540	Loss
Atypical_PIKK_ATM_ATM_ST	Q96J02	ITCH	Q13315	ATM	T214	R215Q	215	Missense	proximal	1	no	6.271	12.923	EPSD	COSMIC	9.540	Gain
Atypical_PIKK_ATM_ATM_ST	Q96J02	ITCH	Q13315	ATM	S221	N219K	219	Missense	proximal	-2	no	11.165	10.949	EPSD	COSMIC	9.540	Down-regulation
Atypical_PIKK_ATM_ATM_ST	Q96J02	ITCH	Q13315	ATM	S221	R215Q	215	Missense	distal	-6	no	11.165	11.308	EPSD	COSMIC	9.540	Up-regulation
Atypical_PIKK_ATM_ATM_ST	Q96J02	ITCH	Q13315	ATM	S221	R215G	215	Missense	distal	-6	no	11.165	11.143	EPSD	COSMIC	9.540	Down-regulation
Atypical_PIKK_ATM_ATM_ST	Q96J02	ITCH	Q13315	ATM	S221	D222N	222	Missense	proximal	1	no	11.165	7.334	EPSD	COSMIC	9.540	Loss
Atypical_PIKK_ATM_ATM_ST	Q96J02	ITCH	Q13315	ATM	S240	S242P	242	Missense	proximal	2	no	9.932	9.477	EPSD	COSMIC	9.540	Loss
Atypical_PIKK_ATM_ATM_ST	Q96J02	ITCH	Q13315	ATM	S240	S242F	242	Missense	proximal	2	no	9.932	8.453	EPSD	COSMIC	9.540	Loss
Atypical_PIKK_ATM_ATM_ST	Q96J02	ITCH	Q13315	ATM	S687	V691F	691	Missense	distal	4	no	10.240	10.762	EPSD	COSMIC	9.540	Up-regulation
Atypical_PIKK_ATM_ATM_ST	Q9BXW9	FANCD2	Q13315	ATM	S222	A225T	225	Missense	distal	3	no	13.575	13.600	PhosphoSitePlus;EPSD	COSMIC	9.540	Up-regulation
Atypical_PIKK_ATM_ATM_ST	Q9BXW9	FANCD2	Q13315	ATM	S319	R315Q	315	Missense	distal	-4	no	12.400	12.766	EPSD	COSMIC;GDSC;CCLE	9.540	Up-regulation
Atypical_PIKK_ATM_ATM_ST	Q9BXW9	FANCD2	Q13315	ATM	S319	Q320K	320	Missense	proximal	1	no	12.400	5.551	EPSD	COSMIC	9.540	Loss
Atypical_PIKK_ATM_ATM_ST	Q9BXW9	FANCD2	Q13315	ATM	S319	R315W	315	Missense	distal	-4	no	12.400	11.924	EPSD	COSMIC	9.540	Down-regulation
Atypical_PIKK_ATM_ATM_ST	Q9BXW9	FANCD2	Q13315	ATM	S338	G339S	339	Missense	proximal	1	no	9.603	4.299	EPSD	COSMIC	9.540	Loss
Atypical_PIKK_ATM_ATM_ST	Q9BXW9	FANCD2	Q13315	ATM	S592	R599T	599	Missense	distal	7	no	10.502	10.484	EPSD	COSMIC	9.540	Down-regulation
Atypical_PIKK_ATM_ATM_ST	Q9BXW9	FANCD2	Q13315	ATM	S592	A586V	586	Missense	distal	-6	no	10.502	10.266	EPSD	COSMIC;GDSC	9.540	Down-regulation
Atypical_PIKK_ATM_ATM_ST	Q9BXW9	FANCD2	Q13315	ATM	T596	R599T	599	Missense	distal	3	no	13.484	13.379	EPSD	COSMIC	9.540	Down-regulation
Atypical_PIKK_ATM_ATM_ST	Q9BXW9	FANCD2	Q13315	ATM	T596	S603C	603	Missense	distal	7	no	13.484	13.536	EPSD	COSMIC	9.540	Up-regulation
Atypical_PIKK_ATM_ATM_ST	Q9BXW9	FANCD2	Q13315	ATM	T608	C607F	607	Missense	proximal	-1	no	12.982	12.755	EPSD	COSMIC	9.540	Down-regulation
Atypical_PIKK_ATM_ATM_ST	Q9BXW9	FANCD2	Q13315	ATM	T608	S603C	603	Missense	distal	-5	no	12.982	13.075	EPSD	COSMIC	9.540	Up-regulation
Atypical_PIKK_ATM_ATM_ST	Q9BXW9	FANCD2	Q13315	ATM	T691	G685E	685	Missense	distal	-6	no	14.390	14.779	EPSD;PhosphoSitePlus	COSMIC	9.540	Up-regulation
Atypical_PIKK_ATM_ATM_ST	Q9BXW9	FANCD2	Q13315	ATM	T691	D690N	690	Missense	proximal	-1	no	14.390	14.389	EPSD;PhosphoSitePlus	COSMIC;GDSC	9.540	Down-regulation
Atypical_PIKK_ATM_ATM_ST	Q9BXW9	FANCD2	Q13315	ATM	S717	P714L	714	Missense	distal	-3	no	14.837	14.850	EPSD;PhosphoSitePlus	COSMIC	9.540	Up-regulation
Atypical_PIKK_ATM_ATM_ST	Q9BXW9	FANCD2	Q13315	ATM	S717	G713D	713	Missense	distal	-4	no	14.837	15.621	EPSD;PhosphoSitePlus	COSMIC	9.540	Up-regulation
Atypical_PIKK_ATM_ATM_ST	Q9BXW9	FANCD2	Q13315	ATM	S784	N791S	791	Missense	distal	7	no	10.251	10.236	EPSD	COSMIC	9.540	Down-regulation
Atypical_PIKK_ATM_ATM_ST	Q9BXW9	FANCD2	Q13315	ATM	S784	L788F	788	Missense	distal	4	no	10.251	10.737	EPSD	COSMIC	9.540	Up-regulation
Atypical_PIKK_ATM_ATM_ST	Q9BXW9	FANCD2	Q13315	ATM	S882	S881F	881	Missense	proximal	-1	no	10.665	10.239	EPSD	COSMIC	9.540	Down-regulation
Atypical_PIKK_ATM_ATM_ST	Q9BXW9	FANCD2	Q13315	ATM	S882	D875N	875	Missense	distal	-7	no	10.665	10.701	EPSD	COSMIC	9.540	Up-regulation
Atypical_PIKK_ATM_ATM_ST	Q9BXW9	FANCD2	Q13315	ATM	S886	S881F	881	Missense	distal	-5	no	10.619	10.943	EPSD	COSMIC	9.540	Up-regulation
Atypical_PIKK_ATM_ATM_ST	Q9BXW9	FANCD2	Q13315	ATM	T896	G901V	901	Missense	distal	5	no	9.883	9.917	EPSD	COSMIC	9.540	Up-regulation
Atypical_PIKK_ATM_ATM_ST	Q9BXW9	FANCD2	Q13315	ATM	T896	R900K	900	Missense	distal	4	no	9.883	9.781	EPSD	COSMIC	9.540	Down-regulation
Atypical_PIKK_ATM_ATM_ST	Q9BXW9	FANCD2	Q13315	ATM	T981	T981I	981	Missense	central	0	yes	9.631	0.000	EPSD	COSMIC	9.540	Loss
Atypical_PIKK_ATM_ATM_ST	Q9BXW9	FANCD2	Q13315	ATM	S1096	R1097Q	1097	Missense	proximal	1	no	8.309	14.961	EPSD	COSMIC;GDSC;CCLE	9.540	Gain
Atypical_PIKK_ATM_ATM_ST	Q9BXW9	FANCD2	Q13315	ATM	S1257	A1254S	1254	Missense	distal	-3	no	16.719	17.164	EPSD	COSMIC	9.540	Up-regulation
Atypical_PIKK_ATM_ATM_ST	Q9BXW9	FANCD2	Q13315	ATM	S1412	S1417P	1417	Missense	distal	5	no	10.826	11.008	EPSD	COSMIC	9.540	Up-regulation
Atypical_PIKK_ATM_ATM_ST	Q9BXW9	FANCD2	Q13315	ATM	S1412	S1412G	1412	Missense	central	0	yes	10.826	0.000	EPSD	COSMIC	9.540	Loss
Atypical_PIKK_ATM_ATM_ST	Q9BXW9	FANCD2	Q13315	ATM	S1412	S1412N	1412	Missense	central	0	yes	10.826	0.000	EPSD	COSMIC	9.540	Loss
Atypical_PIKK_ATM_ATM_ST	Q9BXW9	FANCD2	Q13315	ATM	S1418	S1417P	1417	Missense	proximal	-1	no	15.697	15.404	EPSD	COSMIC	9.540	Down-regulation
Atypical_PIKK_ATM_ATM_ST	Q9BXW9	FANCD2	Q13315	ATM	S1418	S1412G	1412	Missense	distal	-6	no	15.697	15.495	EPSD	COSMIC	9.540	Down-regulation
Atypical_PIKK_ATM_ATM_ST	Q9BXW9	FANCD2	Q13315	ATM	S1418	S1412N	1412	Missense	distal	-6	no	15.697	15.581	EPSD	COSMIC	9.540	Down-regulation
Atypical_PIKK_ATM_ATM_ST	Q9BXW9	FANCD2	Q13315	ATM	S1443	D1449V	1449	Missense	distal	6	no	10.763	10.761	EPSD	COSMIC	9.540	Down-regulation
Atypical_PIKK_ATM_ATM_ST	Q9BXW9	FANCD2	Q13315	ATM	S1443	G1437A	1437	Missense	distal	-6	no	10.763	10.944	EPSD	COSMIC	9.540	Up-regulation
Atypical_PIKK_ATM_ATM_ST	Q9BXW9	FANCD2	Q13315	ATM	S1446	D1449V	1449	Missense	distal	3	no	12.229	12.389	EPSD	COSMIC	9.540	Up-regulation
Atypical_PIKK_ATM_ATM_ST	Q9BXW9	FANCD2	Q13315	ATM	S1450	D1449V	1449	Missense	proximal	-1	no	9.570	9.201	EPSD	COSMIC	9.540	Loss
Atypical_PIKK_ATM_ATM_ST	Q6PCD5	RFWD3	Q13315	ATM	S46	S51Y	51	Missense	distal	5	no	14.627	14.691	EPSD;PhosphoSitePlus	COSMIC	9.540	Up-regulation
Atypical_PIKK_ATM_ATM_ST	Q6PCD5	RFWD3	Q13315	ATM	S46	V49L	49	Missense	distal	3	no	14.627	14.565	EPSD;PhosphoSitePlus	COSMIC;CCLE	9.540	Down-regulation
Atypical_PIKK_ATM_ATM_ST	Q6PCD5	RFWD3	Q13315	ATM	S46	V44I	44	Missense	proximal	-2	no	14.627	14.602	EPSD;PhosphoSitePlus	COSMIC	9.540	Down-regulation
Atypical_PIKK_ATM_ATM_ST	Q6PCD5	RFWD3	Q13315	ATM	S46	V39A	39	Missense	distal	-7	no	14.627	15.010	EPSD;PhosphoSitePlus	COSMIC	9.540	Up-regulation
Atypical_PIKK_ATM_ATM_ST	Q6PCD5	RFWD3	Q13315	ATM	S46	D42E	42	Missense	distal	-4	no	14.627	14.909	EPSD;PhosphoSitePlus	COSMIC	9.540	Up-regulation
Atypical_PIKK_ATM_ATM_ST	Q6PCD5	RFWD3	Q13315	ATM	S63	P68L	68	Missense	distal	5	no	15.780	15.763	PhosphoSitePlus;EPSD	COSMIC	9.540	Down-regulation
Atypical_PIKK_ATM_ATM_ST	Q6PCD5	RFWD3	Q13315	ATM	S63	P57T	57	Missense	distal	-6	no	15.780	15.769	PhosphoSitePlus;EPSD	COSMIC	9.540	Down-regulation
Atypical_PIKK_ATM_ATM_ST	Q6PCD5	RFWD3	Q13315	ATM	S63	A58V	58	Missense	distal	-5	no	15.780	15.900	PhosphoSitePlus;EPSD	COSMIC	9.540	Up-regulation
Atypical_PIKK_ATM_ATM_ST	Q6PCD5	RFWD3	Q13315	ATM	S408	S408R	408	Missense	central	0	yes	12.778	0.000	EPSD	COSMIC	9.540	Loss
Atypical_PIKK_ATM_ATM_ST	Q6PCD5	RFWD3	Q13315	ATM	S428	K433E	433	Missense	distal	5	no	10.097	9.922	EPSD	COSMIC	9.540	Down-regulation
Atypical_PIKK_ATM_ATM_ST	Q6PCD5	RFWD3	Q13315	ATM	S490	T484I	484	Missense	distal	-6	no	15.096	14.764	EPSD	COSMIC	9.540	Down-regulation
Atypical_PIKK_ATM_ATM_ST	Q6PCD5	RFWD3	Q13315	ATM	S490	Y492C	492	Missense	proximal	2	no	15.096	14.703	EPSD	COSMIC	9.540	Down-regulation
Atypical_PIKK_ATM_ATM_ST	Q9UQR1	ZNF148	Q13315	ATM	S23	I17T	17	Missense	distal	-6	no	10.657	10.988	EPSD	COSMIC	9.540	Up-regulation
Atypical_PIKK_ATM_ATM_ST	Q9UQR1	ZNF148	Q13315	ATM	S202	Q203H	203	Missense	proximal	1	no	12.906	-2.003	PhosphoSitePlus	COSMIC	9.540	Loss
Atypical_PIKK_ATM_ATM_ST	Q9UQR1	ZNF148	Q13315	ATM	S202	G195V	195	Missense	distal	-7	no	12.906	12.938	PhosphoSitePlus	COSMIC	9.540	Up-regulation
Atypical_PIKK_ATM_ATM_ST	Q9UQR1	ZNF148	Q13315	ATM	S250	H249Y	249	Missense	proximal	-1	no	9.873	10.028	EPSD	COSMIC	9.540	Up-regulation
Atypical_PIKK_ATM_ATM_ST	Q9UQR1	ZNF148	Q13315	ATM	S250	G251R	251	Missense	proximal	1	no	9.873	9.695	EPSD	COSMIC	9.540	Down-regulation
Atypical_PIKK_ATM_ATM_ST	Q9UQR1	ZNF148	Q13315	ATM	S306	N310S	310	Missense	distal	4	no	9.859	9.732	EPSD	COSMIC	9.540	Down-regulation
Atypical_PIKK_ATM_ATM_ST	Q9UQR1	ZNF148	Q13315	ATM	S625	N629K	629	Missense	distal	4	no	9.773	9.726	EPSD	COSMIC	9.540	Down-regulation
Atypical_PIKK_ATM_ATM_ST	Q9UQR1	ZNF148	Q13315	ATM	S625	N619S	619	Missense	distal	-6	no	9.773	9.889	EPSD	COSMIC	9.540	Up-regulation
Atypical_PIKK_ATM_ATM_ST	Q9UQR1	ZNF148	Q13315	ATM	S625	N619I	619	Missense	distal	-6	no	9.773	9.488	EPSD	COSMIC	9.540	Loss
Atypical_PIKK_ATM_ATM_ST	Q9UQR1	ZNF148	Q13315	ATM	S625	T632A	632	Missense	distal	7	no	9.773	9.788	EPSD	COSMIC	9.540	Up-regulation
Atypical_PIKK_ATM_ATM_ST	Q9UQR1	ZNF148	Q13315	ATM	S665	R660Q	660	Missense	distal	-5	no	9.667	9.457	EPSD	COSMIC;GDSC;CCLE	9.540	Loss
Atypical_PIKK_ATM_ATM_ST	Q9UQR1	ZNF148	Q13315	ATM	S665	G662L	662	Missense	distal	-3	no	9.667	9.597	EPSD	COSMIC	9.540	Down-regulation
Atypical_PIKK_ATM_ATM_ST	Q9UQR1	ZNF148	Q13315	ATM	T670	S674F	674	Missense	distal	4	no	8.866	9.694	EPSD	COSMIC	9.540	Gain
Atypical_PIKK_ATM_ATM_ST	Q9UQR1	ZNF148	Q13315	ATM	S683	H685R	685	Missense	proximal	2	no	12.936	12.620	EPSD	COSMIC	9.540	Down-regulation
Atypical_PIKK_ATM_ATM_ST	Q9UQR1	ZNF148	Q13315	ATM	S683	Q684R	684	Missense	proximal	1	no	12.936	6.285	EPSD	COSMIC	9.540	Loss
Atypical_PIKK_ATM_ATM_ST	Q9UQR1	ZNF148	Q13315	ATM	S683	P688S	688	Missense	distal	5	no	12.936	12.755	EPSD	COSMIC	9.540	Down-regulation
Atypical_PIKK_ATM_ATM_ST	Q9UQR1	ZNF148	Q13315	ATM	T702	Q708E	708	Missense	distal	6	no	14.876	14.922	EPSD	COSMIC	9.540	Up-regulation
Atypical_PIKK_ATM_ATM_ST	Q9UQR1	ZNF148	Q13315	ATM	S784	G790A	790	Missense	distal	6	no	13.254	13.279	EPSD	COSMIC	9.540	Up-regulation
Atypical_PIKK_ATM_ATM_ST	Q9UQR1	ZNF148	Q13315	ATM	S784	T789I	789	Missense	distal	5	no	13.254	13.480	EPSD	COSMIC	9.540	Up-regulation
Atypical_PIKK_ATM_ATM_ST	Q9UQR1	ZNF148	Q13315	ATM	S784	G780W	780	Missense	distal	-4	no	13.254	12.756	EPSD	COSMIC	9.540	Down-regulation
Atypical_PIKK_ATM_ATM_ST	Q96RL1	UIMC1	Q13315	ATM	S101	A96T	96	Missense	distal	-5	no	14.002	13.921	EPSD	COSMIC	9.540	Down-regulation
Atypical_PIKK_ATM_ATM_ST	Q96RL1	UIMC1	Q13315	ATM	S140	P138S	138	Missense	proximal	-2	no	16.313	16.550	EPSD	COSMIC	9.540	Up-regulation
Atypical_PIKK_ATM_ATM_ST	Q96RL1	UIMC1	Q13315	ATM	S140	P138L	138	Missense	proximal	-2	no	16.313	16.160	EPSD	COSMIC;GDSC;CCLE	9.540	Down-regulation
Atypical_PIKK_ATM_ATM_ST	Q96RL1	UIMC1	Q13315	ATM	S198	D202V	202	Missense	distal	4	no	11.879	11.977	EPSD	COSMIC	9.540	Up-regulation
Atypical_PIKK_ATM_ATM_ST	Q96RL1	UIMC1	Q13315	ATM	S198	S204L	204	Missense	distal	6	no	11.879	11.823	EPSD	COSMIC	9.540	Down-regulation
Atypical_PIKK_ATM_ATM_ST	Q96RL1	UIMC1	Q13315	ATM	S198	P193L	193	Missense	distal	-5	no	11.879	11.898	EPSD	COSMIC	9.540	Up-regulation
Atypical_PIKK_ATM_ATM_ST	Q96RL1	UIMC1	Q13315	ATM	S198	E191D	191	Missense	distal	-7	no	11.879	11.301	EPSD	COSMIC	9.540	Down-regulation
Atypical_PIKK_ATM_ATM_ST	Q96RL1	UIMC1	Q13315	ATM	S205	F209S	209	Missense	distal	4	no	14.539	13.711	PhosphoSitePlus	COSMIC	9.540	Down-regulation
Atypical_PIKK_ATM_ATM_ST	Q96RL1	UIMC1	Q13315	ATM	S205	D202V	202	Missense	distal	-3	no	14.539	14.712	PhosphoSitePlus	COSMIC	9.540	Up-regulation
Atypical_PIKK_ATM_ATM_ST	Q96RL1	UIMC1	Q13315	ATM	S205	V212A	212	Missense	distal	7	no	14.539	14.521	PhosphoSitePlus	COSMIC	9.540	Down-regulation
Atypical_PIKK_ATM_ATM_ST	Q96RL1	UIMC1	Q13315	ATM	S205	S198T	198	Missense	distal	-7	no	14.539	14.458	PhosphoSitePlus	COSMIC	9.540	Down-regulation
Atypical_PIKK_ATM_ATM_ST	Q96RL1	UIMC1	Q13315	ATM	S205	S204L	204	Missense	proximal	-1	no	14.539	14.404	PhosphoSitePlus	COSMIC	9.540	Down-regulation
Atypical_PIKK_ATM_ATM_ST	Q96RL1	UIMC1	Q13315	ATM	T228	E235Q	235	Missense	distal	7	no	15.549	15.563	EPSD	COSMIC	9.540	Up-regulation
Atypical_PIKK_ATM_ATM_ST	Q96RL1	UIMC1	Q13315	ATM	S397	H398Q	398	Missense	proximal	1	no	-1.596	13.313	EPSD	COSMIC	9.540	Gain
Atypical_PIKK_ATM_ATM_ST	Q96RL1	UIMC1	Q13315	ATM	S402	T409P	409	Missense	distal	7	no	15.510	15.512	EPSD	COSMIC	9.540	Up-regulation
Atypical_PIKK_ATM_ATM_ST	Q96RL1	UIMC1	Q13315	ATM	S402	H398Q	398	Missense	distal	-4	no	15.510	15.745	EPSD	COSMIC	9.540	Up-regulation
Atypical_PIKK_ATM_ATM_ST	Q96RL1	UIMC1	Q13315	ATM	S419	T426I	426	Missense	distal	7	no	16.206	16.220	EPSD	COSMIC	9.540	Up-regulation
Atypical_PIKK_ATM_ATM_ST	Q96RL1	UIMC1	Q13315	ATM	T448	T455I	455	Missense	distal	7	no	11.381	11.396	EPSD	COSMIC	9.540	Up-regulation
Atypical_PIKK_ATM_ATM_ST	Q96RL1	UIMC1	Q13315	ATM	T448	E454D	454	Missense	distal	6	no	11.381	11.335	EPSD	COSMIC	9.540	Down-regulation
Atypical_PIKK_ATM_ATM_ST	Q96RL1	UIMC1	Q13315	ATM	T448	C445F	445	Missense	distal	-3	no	11.381	12.286	EPSD	COSMIC	9.540	Up-regulation
Atypical_PIKK_ATM_ATM_ST	Q96RL1	UIMC1	Q13315	ATM	S453	T455I	455	Missense	proximal	2	no	10.311	9.888	EPSD	COSMIC	9.540	Down-regulation
Atypical_PIKK_ATM_ATM_ST	Q96RL1	UIMC1	Q13315	ATM	S453	E454D	454	Missense	proximal	1	no	10.311	10.176	EPSD	COSMIC	9.540	Down-regulation
Atypical_PIKK_ATM_ATM_ST	Q96RL1	UIMC1	Q13315	ATM	S463	I469M	469	Missense	distal	6	no	10.005	10.016	EPSD	COSMIC	9.540	Up-regulation
Atypical_PIKK_ATM_ATM_ST	Q96RL1	UIMC1	Q13315	ATM	S597	G596R	596	Missense	proximal	-1	no	9.817	9.634	EPSD	COSMIC	9.540	Down-regulation
Atypical_PIKK_ATM_ATM_ST	Q96RL1	UIMC1	Q13315	ATM	S637	H634Y	634	Missense	distal	-3	no	9.535	9.573	EPSD	COSMIC	9.540	Gain
Atypical_PIKK_ATM_ATM_ST	Q96RL1	UIMC1	Q13315	ATM	S644	K642N	642	Missense	proximal	-2	no	10.025	10.240	EPSD	COSMIC	9.540	Up-regulation
Atypical_PIKK_ATM_ATM_ST	Q96T60	PNKP	Q13315	ATM	S114	T118N	118	Missense	distal	4	no	15.948	15.987	EPSD;PhosphoSitePlus	COSMIC	9.540	Up-regulation
Atypical_PIKK_ATM_ATM_ST	Q96T60	PNKP	Q13315	ATM	S114	S114P	114	Missense	central	0	yes	15.948	0.000	EPSD;PhosphoSitePlus	COSMIC	9.540	Loss
Atypical_PIKK_ATM_ATM_ST	Q96T60	PNKP	Q13315	ATM	S126	R131I	131	Missense	distal	5	no	14.074	14.119	PhosphoSitePlus;EPSD	COSMIC	9.540	Up-regulation
Atypical_PIKK_ATM_ATM_ST	Q96T60	PNKP	Q13315	ATM	S126	E129K	129	Missense	distal	3	no	14.074	14.363	PhosphoSitePlus;EPSD	COSMIC	9.540	Up-regulation
Atypical_PIKK_ATM_ATM_ST	Q96T60	PNKP	Q13315	ATM	S126	V125M	125	Missense	proximal	-1	no	14.074	14.207	PhosphoSitePlus;EPSD	COSMIC	9.540	Up-regulation
Atypical_PIKK_ATM_ATM_ST	Q96T60	PNKP	Q13315	ATM	S126	P123S	123	Missense	distal	-3	no	14.074	13.878	PhosphoSitePlus;EPSD	COSMIC	9.540	Down-regulation
Atypical_PIKK_ATM_ATM_ST	O75943	RAD17	Q13315	ATM	S81	Q74P	74	Missense	distal	-7	no	11.061	11.024	EPSD	COSMIC	9.540	Down-regulation
Atypical_PIKK_ATM_ATM_ST	O75943	RAD17	Q13315	ATM	T633	S628Y	628	Missense	distal	-5	no	12.732	12.756	PhosphoSitePlus;EPSD	COSMIC	9.540	Up-regulation
Atypical_PIKK_ATM_ATM_ST	O75943	RAD17	Q13315	ATM	S646	P644L	644	Missense	proximal	-2	no	15.374	15.221	EPSD;PhosphoSitePlus	COSMIC	9.540	Down-regulation
Atypical_PIKK_ATM_ATM_ST	Q9NS23	RASSF1	Q13315	ATM	S135	A137S	137	Missense	proximal	2	no	14.799	15.382	PhosphoSitePlus;EPSD	COSMIC	9.540	Up-regulation
Atypical_PIKK_ATM_ATM_ST	Q9NS23	RASSF1	Q13315	ATM	S135	I139L	139	Missense	distal	4	no	14.799	14.478	PhosphoSitePlus;EPSD	COSMIC	9.540	Down-regulation
Atypical_PIKK_ATM_ATM_ST	Q9NS23	RASSF1	Q13315	ATM	S135	I139T	139	Missense	distal	4	no	14.799	14.224	PhosphoSitePlus;EPSD	COSMIC;GDSC;CCLE	9.540	Down-regulation
Atypical_PIKK_ATM_ATM_ST	Q9NS23	RASSF1	Q13315	ATM	S135	W129C	129	Missense	distal	-6	no	14.799	14.768	PhosphoSitePlus;EPSD	COSMIC	9.540	Down-regulation
Atypical_PIKK_ATM_ATM_ST	Q9NS23	RASSF1	Q13315	ATM	S188	L189Q	189	Missense	proximal	1	no	7.457	13.813	EPSD	COSMIC	9.540	Gain
Atypical_PIKK_ATM_ATM_ST	Q01094	E2F1	Q13315	ATM	S131	R127L	127	Missense	distal	-4	no	9.642	9.513	EPSD	COSMIC	9.540	Loss
Atypical_PIKK_ATM_ATM_ST	Q01094	E2F1	Q13315	ATM	S307	P312L	312	Missense	distal	5	no	9.855	9.838	EPSD	COSMIC	9.540	Down-regulation
Atypical_PIKK_ATM_ATM_ST	Q01094	E2F1	Q13315	ATM	S313	S318F	318	Missense	distal	5	no	13.870	14.176	EPSD	COSMIC	9.540	Up-regulation
Atypical_PIKK_ATM_ATM_ST	Q01094	E2F1	Q13315	ATM	S313	P312L	312	Missense	proximal	-1	no	13.870	14.027	EPSD	COSMIC	9.540	Up-regulation
Atypical_PIKK_ATM_ATM_ST	Q01094	E2F1	Q13315	ATM	S318	S318F	318	Missense	central	0	yes	9.741	0.000	EPSD	COSMIC	9.540	Loss
Atypical_PIKK_ATM_ATM_ST	Q01094	E2F1	Q13315	ATM	S318	P312L	312	Missense	distal	-6	no	9.741	9.511	EPSD	COSMIC	9.540	Loss
Atypical_PIKK_ATM_ATM_ST	Q01094	E2F1	Q13315	ATM	S347	S341F	341	Missense	distal	-6	no	14.776	14.245	EPSD	COSMIC	9.540	Down-regulation
Atypical_PIKK_ATM_ATM_ST	Q01094	E2F1	Q13315	ATM	S347	P346S	346	Missense	proximal	-1	no	14.776	15.068	EPSD	COSMIC;GDSC	9.540	Up-regulation
Atypical_PIKK_ATM_ATM_ST	Q01094	E2F1	Q13315	ATM	S347	L350V	350	Missense	distal	3	no	14.776	14.838	EPSD	COSMIC	9.540	Up-regulation
Atypical_PIKK_ATM_ATM_ST	Q01094	E2F1	Q13315	ATM	S375	S382L	382	Missense	distal	7	no	9.644	9.663	EPSD	COSMIC	9.540	Up-regulation
Atypical_PIKK_ATM_ATM_ST	Q00987	MDM2	Q13315	ATM	S17	E23K	23	Missense	distal	6	no	15.241	15.195	EPSD	COSMIC	9.540	Down-regulation
Atypical_PIKK_ATM_ATM_ST	Q00987	MDM2	Q13315	ATM	S17	T10I	10	Missense	distal	-7	no	15.241	14.658	EPSD	COSMIC	9.540	Down-regulation
Atypical_PIKK_ATM_ATM_ST	Q00987	MDM2	Q13315	ATM	S17	D11N	11	Missense	distal	-6	no	15.241	15.152	EPSD	COSMIC	9.540	Down-regulation
Atypical_PIKK_ATM_ATM_ST	Q00987	MDM2	Q13315	ATM	S17	T16I	16	Missense	proximal	-1	no	15.241	15.010	EPSD	COSMIC	9.540	Down-regulation
Atypical_PIKK_ATM_ATM_ST	Q00987	MDM2	Q13315	ATM	S118	E114D	114	Missense	distal	-4	no	10.656	10.373	EPSD	COSMIC	9.540	Down-regulation
Atypical_PIKK_ATM_ATM_ST	Q00987	MDM2	Q13315	ATM	S118	D117N	117	Missense	proximal	-1	no	10.656	10.655	EPSD	COSMIC	9.540	Down-regulation
Atypical_PIKK_ATM_ATM_ST	Q00987	MDM2	Q13315	ATM	S118	E124K	124	Missense	distal	6	no	10.656	10.611	EPSD	COSMIC	9.540	Down-regulation
Atypical_PIKK_ATM_ATM_ST	Q00987	MDM2	Q13315	ATM	S118	S121F	121	Missense	distal	3	no	10.656	11.238	EPSD	COSMIC	9.540	Up-regulation
Atypical_PIKK_ATM_ATM_ST	Q00987	MDM2	Q13315	ATM	S148	S149Y	149	Missense	proximal	1	no	4.441	10.502	EPSD	COSMIC	9.540	Gain
Atypical_PIKK_ATM_ATM_ST	Q00987	MDM2	Q13315	ATM	S166	E170D	170	Missense	distal	4	no	10.142	10.647	EPSD	COSMIC	9.540	Up-regulation
Atypical_PIKK_ATM_ATM_ST	Q00987	MDM2	Q13315	ATM	S166	S160F	160	Missense	distal	-6	no	10.142	9.610	EPSD	COSMIC	9.540	Down-regulation
Atypical_PIKK_ATM_ATM_ST	Q00987	MDM2	Q13315	ATM	S166	S159R	159	Missense	distal	-7	no	10.142	9.743	EPSD	COSMIC	9.540	Down-regulation
Atypical_PIKK_ATM_ATM_ST	Q00987	MDM2	Q13315	ATM	S166	S159G	159	Missense	distal	-7	no	10.142	9.629	EPSD	COSMIC	9.540	Down-regulation
Atypical_PIKK_ATM_ATM_ST	Q00987	MDM2	Q13315	ATM	S166	D173Y	173	Missense	distal	7	no	10.142	10.167	EPSD	COSMIC	9.540	Up-regulation
Atypical_PIKK_ATM_ATM_ST	Q00987	MDM2	Q13315	ATM	S166	S166C	166	Missense	central	0	yes	10.142	0.000	EPSD	COSMIC	9.540	Loss
Atypical_PIKK_ATM_ATM_ST	Q00987	MDM2	Q13315	ATM	S166	E167Q	167	Missense	proximal	1	no	10.142	16.038	EPSD	COSMIC	9.540	Up-regulation
Atypical_PIKK_ATM_ATM_ST	Q00987	MDM2	Q13315	ATM	S166	S159N	159	Missense	distal	-7	no	10.142	9.955	EPSD	COSMIC	9.540	Down-regulation
Atypical_PIKK_ATM_ATM_ST	Q00987	MDM2	Q13315	ATM	S166	R161T	161	Missense	distal	-5	no	10.142	9.977	EPSD	COSMIC	9.540	Down-regulation
Atypical_PIKK_ATM_ATM_ST	Q00987	MDM2	Q13315	ATM	S166	S166F	166	Missense	central	0	yes	10.142	0.000	EPSD	COSMIC	9.540	Loss
Atypical_PIKK_ATM_ATM_ST	Q00987	MDM2	Q13315	ATM	S172	E170D	170	Missense	proximal	-2	no	9.908	9.429	EPSD	COSMIC	9.540	Loss
Atypical_PIKK_ATM_ATM_ST	Q00987	MDM2	Q13315	ATM	S172	E178K	178	Missense	distal	6	no	9.908	9.862	EPSD	COSMIC	9.540	Down-regulation
Atypical_PIKK_ATM_ATM_ST	Q00987	MDM2	Q13315	ATM	S172	S176F	176	Missense	distal	4	no	9.908	10.736	EPSD	COSMIC	9.540	Up-regulation
Atypical_PIKK_ATM_ATM_ST	Q00987	MDM2	Q13315	ATM	S172	G177D	177	Missense	distal	5	no	9.908	9.816	EPSD	COSMIC	9.540	Down-regulation
Atypical_PIKK_ATM_ATM_ST	Q00987	MDM2	Q13315	ATM	S172	R179P	179	Missense	distal	7	no	9.908	9.892	EPSD	COSMIC	9.540	Down-regulation
Atypical_PIKK_ATM_ATM_ST	Q00987	MDM2	Q13315	ATM	S172	D173Y	173	Missense	proximal	1	no	9.908	10.223	EPSD	COSMIC	9.540	Up-regulation
Atypical_PIKK_ATM_ATM_ST	Q00987	MDM2	Q13315	ATM	S172	S166C	166	Missense	distal	-6	no	9.908	9.528	EPSD	COSMIC	9.540	Loss
Atypical_PIKK_ATM_ATM_ST	Q00987	MDM2	Q13315	ATM	S172	E167Q	167	Missense	distal	-5	no	9.908	9.939	EPSD	COSMIC	9.540	Up-regulation
Atypical_PIKK_ATM_ATM_ST	Q00987	MDM2	Q13315	ATM	S172	S166F	166	Missense	distal	-6	no	9.908	9.376	EPSD	COSMIC	9.540	Loss
Atypical_PIKK_ATM_ATM_ST	Q00987	MDM2	Q13315	ATM	S176	E170D	170	Missense	distal	-6	no	10.733	10.518	EPSD	COSMIC	9.540	Down-regulation
Atypical_PIKK_ATM_ATM_ST	Q00987	MDM2	Q13315	ATM	S176	R183H	183	Missense	distal	7	no	10.733	10.727	EPSD	COSMIC	9.540	Down-regulation
Atypical_PIKK_ATM_ATM_ST	Q00987	MDM2	Q13315	ATM	S176	E178K	178	Missense	proximal	2	no	10.733	9.402	EPSD	COSMIC	9.540	Loss
Atypical_PIKK_ATM_ATM_ST	Q00987	MDM2	Q13315	ATM	S176	S176F	176	Missense	central	0	yes	10.733	0.000	EPSD	COSMIC	9.540	Loss
Atypical_PIKK_ATM_ATM_ST	Q00987	MDM2	Q13315	ATM	S176	G177D	177	Missense	proximal	1	no	10.733	11.175	EPSD	COSMIC	9.540	Up-regulation
Atypical_PIKK_ATM_ATM_ST	Q00987	MDM2	Q13315	ATM	S176	R183C	183	Missense	distal	7	no	10.733	10.750	EPSD	COSMIC	9.540	Up-regulation
Atypical_PIKK_ATM_ATM_ST	Q00987	MDM2	Q13315	ATM	S176	R179P	179	Missense	distal	3	no	10.733	10.699	EPSD	COSMIC	9.540	Down-regulation
Atypical_PIKK_ATM_ATM_ST	Q00987	MDM2	Q13315	ATM	S176	D173Y	173	Missense	distal	-3	no	10.733	10.619	EPSD	COSMIC	9.540	Down-regulation
Atypical_PIKK_ATM_ATM_ST	Q00987	MDM2	Q13315	ATM	S186	R183H	183	Missense	distal	-3	no	11.244	10.598	EPSD	COSMIC	9.540	Down-regulation
Atypical_PIKK_ATM_ATM_ST	Q00987	MDM2	Q13315	ATM	S186	I189V	189	Missense	distal	3	no	11.244	11.086	EPSD	COSMIC	9.540	Down-regulation
Atypical_PIKK_ATM_ATM_ST	Q00987	MDM2	Q13315	ATM	S186	K185R	185	Missense	proximal	-1	no	11.244	11.062	EPSD	COSMIC	9.540	Down-regulation
Atypical_PIKK_ATM_ATM_ST	Q00987	MDM2	Q13315	ATM	S186	S190F	190	Missense	distal	4	no	11.244	12.071	EPSD	COSMIC	9.540	Up-regulation
Atypical_PIKK_ATM_ATM_ST	Q00987	MDM2	Q13315	ATM	S186	R183C	183	Missense	distal	-3	no	11.244	10.671	EPSD	COSMIC	9.540	Down-regulation
Atypical_PIKK_ATM_ATM_ST	Q00987	MDM2	Q13315	ATM	S186	R179P	179	Missense	distal	-7	no	11.244	11.406	EPSD	COSMIC	9.540	Up-regulation
Atypical_PIKK_ATM_ATM_ST	Q00987	MDM2	Q13315	ATM	S190	R183H	183	Missense	distal	-7	no	11.378	11.463	EPSD	COSMIC	9.540	Up-regulation
Atypical_PIKK_ATM_ATM_ST	Q00987	MDM2	Q13315	ATM	S190	I189V	189	Missense	proximal	-1	no	11.378	11.175	EPSD	COSMIC	9.540	Down-regulation
Atypical_PIKK_ATM_ATM_ST	Q00987	MDM2	Q13315	ATM	S190	K185R	185	Missense	distal	-5	no	11.378	11.537	EPSD	COSMIC	9.540	Up-regulation
Atypical_PIKK_ATM_ATM_ST	Q00987	MDM2	Q13315	ATM	S190	S190F	190	Missense	central	0	yes	11.378	0.000	EPSD	COSMIC	9.540	Loss
Atypical_PIKK_ATM_ATM_ST	Q00987	MDM2	Q13315	ATM	S190	R183C	183	Missense	distal	-7	no	11.378	11.103	EPSD	COSMIC	9.540	Down-regulation
Atypical_PIKK_ATM_ATM_ST	Q00987	MDM2	Q13315	ATM	S190	S196F	196	Missense	distal	6	no	11.378	11.302	EPSD	COSMIC	9.540	Down-regulation
Atypical_PIKK_ATM_ATM_ST	Q00987	MDM2	Q13315	ATM	S196	I189V	189	Missense	distal	-7	no	10.268	10.452	EPSD	COSMIC	9.540	Up-regulation
Atypical_PIKK_ATM_ATM_ST	Q00987	MDM2	Q13315	ATM	S196	L199Q	199	Missense	distal	3	no	10.268	10.069	EPSD	COSMIC	9.540	Down-regulation
Atypical_PIKK_ATM_ATM_ST	Q00987	MDM2	Q13315	ATM	S196	L199P	199	Missense	distal	3	no	10.268	10.137	EPSD	COSMIC	9.540	Down-regulation
Atypical_PIKK_ATM_ATM_ST	Q00987	MDM2	Q13315	ATM	S196	V201E	201	Missense	distal	5	no	10.268	9.885	EPSD	COSMIC	9.540	Down-regulation
Atypical_PIKK_ATM_ATM_ST	Q00987	MDM2	Q13315	ATM	S196	S190F	190	Missense	distal	-6	no	10.268	9.736	EPSD	COSMIC	9.540	Down-regulation
Atypical_PIKK_ATM_ATM_ST	Q00987	MDM2	Q13315	ATM	S196	S196F	196	Missense	central	0	yes	10.268	0.000	EPSD	COSMIC	9.540	Loss
Atypical_PIKK_ATM_ATM_ST	Q00987	MDM2	Q13315	ATM	S229	E230Q	230	Missense	proximal	1	no	8.913	14.810	EPSD	COSMIC	9.540	Gain
Atypical_PIKK_ATM_ATM_ST	Q00987	MDM2	Q13315	ATM	S256	L261R	261	Missense	distal	5	no	11.148	11.149	EPSD	COSMIC	9.540	Up-regulation
Atypical_PIKK_ATM_ATM_ST	Q00987	MDM2	Q13315	ATM	S256	E257K	257	Missense	proximal	1	no	11.148	10.196	EPSD	COSMIC	9.540	Down-regulation
Atypical_PIKK_ATM_ATM_ST	Q00987	MDM2	Q13315	ATM	S256	S253Y	253	Missense	distal	-3	no	11.148	11.280	EPSD	COSMIC	9.540	Up-regulation
Atypical_PIKK_ATM_ATM_ST	Q00987	MDM2	Q13315	ATM	S256	E252Q	252	Missense	distal	-4	no	11.148	10.424	EPSD	COSMIC	9.540	Down-regulation
Atypical_PIKK_ATM_ATM_ST	Q00987	MDM2	Q13315	ATM	S256	S262N	262	Missense	distal	6	no	11.148	11.137	EPSD	COSMIC	9.540	Down-regulation
Atypical_PIKK_ATM_ATM_ST	Q00987	MDM2	Q13315	ATM	S256	D255N	255	Missense	proximal	-1	no	11.148	11.147	EPSD	COSMIC	9.540	Down-regulation
Atypical_PIKK_ATM_ATM_ST	Q00987	MDM2	Q13315	ATM	S256	L254V	254	Missense	proximal	-2	no	11.148	10.873	EPSD	COSMIC	9.540	Down-regulation
Atypical_PIKK_ATM_ATM_ST	Q00987	MDM2	Q13315	ATM	S256	E263K	263	Missense	distal	7	no	11.148	11.174	EPSD	COSMIC	9.540	Up-regulation
Atypical_PIKK_ATM_ATM_ST	Q00987	MDM2	Q13315	ATM	S260	L261R	261	Missense	proximal	1	no	10.571	10.276	EPSD	COSMIC	9.540	Down-regulation
Atypical_PIKK_ATM_ATM_ST	Q00987	MDM2	Q13315	ATM	S260	E257K	257	Missense	distal	-3	no	10.571	10.638	EPSD	COSMIC	9.540	Up-regulation
Atypical_PIKK_ATM_ATM_ST	Q00987	MDM2	Q13315	ATM	S260	S253Y	253	Missense	distal	-7	no	10.571	10.276	EPSD	COSMIC	9.540	Down-regulation
Atypical_PIKK_ATM_ATM_ST	Q00987	MDM2	Q13315	ATM	S260	S262N	262	Missense	proximal	2	no	10.571	9.930	EPSD	COSMIC	9.540	Down-regulation
Atypical_PIKK_ATM_ATM_ST	Q00987	MDM2	Q13315	ATM	S260	D255N	255	Missense	distal	-5	no	10.571	10.754	EPSD	COSMIC	9.540	Up-regulation
Atypical_PIKK_ATM_ATM_ST	Q00987	MDM2	Q13315	ATM	S260	L254V	254	Missense	distal	-6	no	10.571	10.603	EPSD	COSMIC	9.540	Up-regulation
Atypical_PIKK_ATM_ATM_ST	Q00987	MDM2	Q13315	ATM	S260	G265E	265	Missense	distal	5	no	10.571	10.222	EPSD	COSMIC	9.540	Down-regulation
Atypical_PIKK_ATM_ATM_ST	Q00987	MDM2	Q13315	ATM	S260	E263K	263	Missense	distal	3	no	10.571	10.860	EPSD	COSMIC	9.540	Up-regulation
Atypical_PIKK_ATM_ATM_ST	Q00987	MDM2	Q13315	ATM	S262	L261R	261	Missense	proximal	-1	no	11.792	11.552	EPSD	COSMIC	9.540	Down-regulation
Atypical_PIKK_ATM_ATM_ST	Q00987	MDM2	Q13315	ATM	S262	E257K	257	Missense	distal	-5	no	11.792	11.873	EPSD	COSMIC	9.540	Up-regulation
Atypical_PIKK_ATM_ATM_ST	Q00987	MDM2	Q13315	ATM	S262	S262N	262	Missense	central	0	yes	11.792	0.000	EPSD	COSMIC	9.540	Loss
Atypical_PIKK_ATM_ATM_ST	Q00987	MDM2	Q13315	ATM	S262	D255N	255	Missense	distal	-7	no	11.792	11.828	EPSD	COSMIC	9.540	Up-regulation
Atypical_PIKK_ATM_ATM_ST	Q00987	MDM2	Q13315	ATM	S262	G265E	265	Missense	distal	3	no	11.792	11.485	EPSD	COSMIC	9.540	Down-regulation
Atypical_PIKK_ATM_ATM_ST	Q00987	MDM2	Q13315	ATM	S262	E263K	263	Missense	proximal	1	no	11.792	10.840	EPSD	COSMIC	9.540	Down-regulation
Atypical_PIKK_ATM_ATM_ST	Q00987	MDM2	Q13315	ATM	S269	D272N	272	Missense	distal	3	no	10.657	10.674	EPSD	COSMIC	9.540	Up-regulation
Atypical_PIKK_ATM_ATM_ST	Q00987	MDM2	Q13315	ATM	S269	Y276C	276	Missense	distal	7	no	10.657	10.675	EPSD	COSMIC	9.540	Up-regulation
Atypical_PIKK_ATM_ATM_ST	Q00987	MDM2	Q13315	ATM	S269	Y276H	276	Missense	distal	7	no	10.657	10.652	EPSD	COSMIC	9.540	Down-regulation
Atypical_PIKK_ATM_ATM_ST	Q00987	MDM2	Q13315	ATM	S269	S262N	262	Missense	distal	-7	no	10.657	10.471	EPSD	COSMIC	9.540	Down-regulation
Atypical_PIKK_ATM_ATM_ST	Q00987	MDM2	Q13315	ATM	S269	G265E	265	Missense	distal	-4	no	10.657	11.724	EPSD	COSMIC	9.540	Up-regulation
Atypical_PIKK_ATM_ATM_ST	Q00987	MDM2	Q13315	ATM	S269	E271D	271	Missense	proximal	2	no	10.657	10.526	EPSD	COSMIC	9.540	Down-regulation
Atypical_PIKK_ATM_ATM_ST	Q00987	MDM2	Q13315	ATM	S269	E263K	263	Missense	distal	-6	no	10.657	10.356	EPSD	COSMIC	9.540	Down-regulation
Atypical_PIKK_ATM_ATM_ST	Q00987	MDM2	Q13315	ATM	S286	G284W	284	Missense	proximal	-2	no	9.990	9.939	EPSD	COSMIC	9.540	Down-regulation
Atypical_PIKK_ATM_ATM_ST	Q00987	MDM2	Q13315	ATM	S286	A283T	283	Missense	distal	-3	no	9.990	10.368	EPSD	COSMIC	9.540	Up-regulation
Atypical_PIKK_ATM_ATM_ST	Q00987	MDM2	Q13315	ATM	S286	Y281H	281	Missense	distal	-5	no	9.990	10.015	EPSD	COSMIC	9.540	Up-regulation
Atypical_PIKK_ATM_ATM_ST	Q00987	MDM2	Q13315	ATM	S286	T279P	279	Missense	distal	-7	no	9.990	9.835	EPSD	COSMIC	9.540	Down-regulation
Atypical_PIKK_ATM_ATM_ST	Q00987	MDM2	Q13315	ATM	S286	E285K	285	Missense	proximal	-1	no	9.990	9.588	EPSD	COSMIC	9.540	Down-regulation
Atypical_PIKK_ATM_ATM_ST	Q00987	MDM2	Q13315	ATM	S286	D287N	287	Missense	proximal	1	no	9.990	6.160	EPSD	COSMIC	9.540	Loss
Atypical_PIKK_ATM_ATM_ST	Q00987	MDM2	Q13315	ATM	S286	F291S	291	Missense	distal	5	no	9.990	9.684	EPSD	COSMIC	9.540	Down-regulation
Atypical_PIKK_ATM_ATM_ST	Q00987	MDM2	Q13315	ATM	S286	E292K	292	Missense	distal	6	no	9.990	9.945	EPSD	COSMIC	9.540	Down-regulation
Atypical_PIKK_ATM_ATM_ST	Q00987	MDM2	Q13315	ATM	T351	G356S	356	Missense	distal	5	no	12.076	11.898	EPSD	COSMIC	9.540	Down-regulation
Atypical_PIKK_ATM_ATM_ST	Q00987	MDM2	Q13315	ATM	T351	E355Q	355	Missense	distal	4	no	12.076	12.408	EPSD	COSMIC	9.540	Up-regulation
Atypical_PIKK_ATM_ATM_ST	Q00987	MDM2	Q13315	ATM	T351	E354K	354	Missense	distal	3	no	12.076	12.365	EPSD	COSMIC	9.540	Up-regulation
Atypical_PIKK_ATM_ATM_ST	Q00987	MDM2	Q13315	ATM	T351	E355K	355	Missense	distal	4	no	12.076	12.454	EPSD	COSMIC	9.540	Up-regulation
Atypical_PIKK_ATM_ATM_ST	Q00987	MDM2	Q13315	ATM	S386	Q384R	384	Missense	proximal	-2	no	14.863	14.544	EPSD;PhosphoSitePlus	COSMIC	9.540	Down-regulation
Atypical_PIKK_ATM_ATM_ST	Q00987	MDM2	Q13315	ATM	S386	D393E	393	Missense	distal	7	no	14.863	14.850	EPSD;PhosphoSitePlus	COSMIC	9.540	Down-regulation
Atypical_PIKK_ATM_ATM_ST	Q00987	MDM2	Q13315	ATM	S386	D393H	393	Missense	distal	7	no	14.863	14.883	EPSD;PhosphoSitePlus	COSMIC	9.540	Up-regulation
Atypical_PIKK_ATM_ATM_ST	Q00987	MDM2	Q13315	ATM	S386	A385V	385	Missense	proximal	-1	no	14.863	14.600	EPSD;PhosphoSitePlus	COSMIC	9.540	Down-regulation
Atypical_PIKK_ATM_ATM_ST	Q00987	MDM2	Q13315	ATM	S386	D379G	379	Missense	distal	-7	no	14.863	14.573	EPSD;PhosphoSitePlus	COSMIC	9.540	Down-regulation
Atypical_PIKK_ATM_ATM_ST	Q00987	MDM2	Q13315	ATM	S388	Q384R	384	Missense	distal	-4	no	15.194	14.828	EPSD	COSMIC	9.540	Down-regulation
Atypical_PIKK_ATM_ATM_ST	Q00987	MDM2	Q13315	ATM	S388	D393E	393	Missense	distal	5	no	15.194	14.937	EPSD	COSMIC	9.540	Down-regulation
Atypical_PIKK_ATM_ATM_ST	Q00987	MDM2	Q13315	ATM	S388	D393H	393	Missense	distal	5	no	15.194	15.247	EPSD	COSMIC	9.540	Up-regulation
Atypical_PIKK_ATM_ATM_ST	Q00987	MDM2	Q13315	ATM	S388	A385V	385	Missense	distal	-3	no	15.194	16.058	EPSD	COSMIC	9.540	Up-regulation
Atypical_PIKK_ATM_ATM_ST	Q00987	MDM2	Q13315	ATM	S395	D393E	393	Missense	proximal	-2	no	14.526	15.005	EPSD;PhosphoSitePlus	COSMIC	9.540	Up-regulation
Atypical_PIKK_ATM_ATM_ST	Q00987	MDM2	Q13315	ATM	S395	D393H	393	Missense	proximal	-2	no	14.526	14.397	EPSD;PhosphoSitePlus	COSMIC	9.540	Down-regulation
Atypical_PIKK_ATM_ATM_ST	Q00987	MDM2	Q13315	ATM	S406	S407R	407	Missense	proximal	1	no	4.526	9.652	EPSD	COSMIC	9.540	Gain
Atypical_PIKK_ATM_ATM_ST	Q00987	MDM2	Q13315	ATM	S406	S407G	407	Missense	proximal	1	no	4.526	9.829	EPSD	COSMIC	9.540	Gain
Atypical_PIKK_ATM_ATM_ST	Q00987	MDM2	Q13315	ATM	S407	S407R	407	Missense	central	0	yes	16.962	0.000	PhosphoSitePlus;EPSD	COSMIC	9.540	Loss
Atypical_PIKK_ATM_ATM_ST	Q00987	MDM2	Q13315	ATM	S407	E413K	413	Missense	distal	6	no	16.962	16.917	PhosphoSitePlus;EPSD	COSMIC	9.540	Down-regulation
Atypical_PIKK_ATM_ATM_ST	Q00987	MDM2	Q13315	ATM	S407	S407G	407	Missense	central	0	yes	16.962	0.000	PhosphoSitePlus;EPSD	COSMIC	9.540	Loss
Atypical_PIKK_ATM_ATM_ST	Q00987	MDM2	Q13315	ATM	S407	E413G	413	Missense	distal	6	no	16.962	16.919	PhosphoSitePlus;EPSD	COSMIC	9.540	Down-regulation
Atypical_PIKK_ATM_ATM_ST	Q00987	MDM2	Q13315	ATM	S407	I403V	403	Missense	distal	-4	no	16.962	16.685	PhosphoSitePlus;EPSD	COSMIC	9.540	Down-regulation
Atypical_PIKK_ATM_ATM_ST	Q00987	MDM2	Q13315	ATM	S407	Y405C	405	Missense	proximal	-2	no	16.962	16.670	PhosphoSitePlus;EPSD	COSMIC	9.540	Down-regulation
Atypical_PIKK_ATM_ATM_ST	Q00987	MDM2	Q13315	ATM	S407	F414I	414	Missense	distal	7	no	16.962	16.934	PhosphoSitePlus;EPSD	COSMIC	9.540	Down-regulation
Atypical_PIKK_ATM_ATM_ST	Q00987	MDM2	Q13315	ATM	S407	S407N	407	Missense	central	0	yes	16.962	0.000	PhosphoSitePlus;EPSD	COSMIC	9.540	Loss
Atypical_PIKK_ATM_ATM_ST	Q00987	MDM2	Q13315	ATM	T419	E413K	413	Missense	distal	-6	no	17.081	16.780	EPSD;PhosphoSitePlus	COSMIC	9.540	Down-regulation
Atypical_PIKK_ATM_ATM_ST	Q00987	MDM2	Q13315	ATM	T419	E413G	413	Missense	distal	-6	no	17.081	16.692	EPSD;PhosphoSitePlus	COSMIC	9.540	Down-regulation
Atypical_PIKK_ATM_ATM_ST	Q00987	MDM2	Q13315	ATM	T419	E415Q	415	Missense	distal	-4	no	17.081	16.358	EPSD;PhosphoSitePlus	COSMIC	9.540	Down-regulation
Atypical_PIKK_ATM_ATM_ST	Q00987	MDM2	Q13315	ATM	T419	T419I	419	Missense	central	0	yes	17.081	0.000	EPSD;PhosphoSitePlus	COSMIC	9.540	Loss
Atypical_PIKK_ATM_ATM_ST	Q00987	MDM2	Q13315	ATM	T419	S425C	425	Missense	distal	6	no	17.081	17.009	EPSD;PhosphoSitePlus	COSMIC	9.540	Down-regulation
Atypical_PIKK_ATM_ATM_ST	Q00987	MDM2	Q13315	ATM	T419	F414I	414	Missense	distal	-5	no	17.081	16.872	EPSD;PhosphoSitePlus	COSMIC	9.540	Down-regulation
Atypical_PIKK_ATM_ATM_ST	Q00987	MDM2	Q13315	ATM	T419	V426A	426	Missense	distal	7	no	17.081	17.063	EPSD;PhosphoSitePlus	COSMIC	9.540	Down-regulation
Atypical_PIKK_ATM_ATM_ST	Q00987	MDM2	Q13315	ATM	S425	V426A	426	Missense	proximal	1	no	4.584	10.705	EPSD;PhosphoSitePlus	COSMIC	9.540	Gain
Atypical_PIKK_ATM_ATM_ST	Q00987	MDM2	Q13315	ATM	S429	A434V	434	Missense	distal	5	no	12.182	12.347	EPSD;PhosphoSitePlus	COSMIC	9.540	Up-regulation
Atypical_PIKK_ATM_ATM_ST	Q00987	MDM2	Q13315	ATM	S429	S425C	425	Missense	distal	-4	no	12.182	10.609	EPSD;PhosphoSitePlus	COSMIC	9.540	Down-regulation
Atypical_PIKK_ATM_ATM_ST	Q00987	MDM2	Q13315	ATM	S429	E436G	436	Missense	distal	7	no	12.182	12.228	EPSD;PhosphoSitePlus	COSMIC	9.540	Up-regulation
Atypical_PIKK_ATM_ATM_ST	Q00987	MDM2	Q13315	ATM	S429	S429R	429	Missense	central	0	yes	12.182	0.000	EPSD;PhosphoSitePlus	COSMIC	9.540	Loss
Atypical_PIKK_ATM_ATM_ST	Q00987	MDM2	Q13315	ATM	S429	V426A	426	Missense	distal	-3	no	12.182	11.319	EPSD;PhosphoSitePlus	COSMIC	9.540	Down-regulation
Atypical_PIKK_ATM_ATM_ST	O96017	CHEK2	Q13315	ATM	S19	H13Y	13	Missense	distal	-6	no	16.504	16.434	EPSD	COSMIC	9.540	Down-regulation
Atypical_PIKK_ATM_ATM_ST	O96017	CHEK2	Q13315	ATM	S19	V25I	25	Missense	distal	6	no	16.504	16.488	EPSD	COSMIC	9.540	Down-regulation
Atypical_PIKK_ATM_ATM_ST	O96017	CHEK2	Q13315	ATM	S19	H13N	13	Missense	distal	-6	no	16.504	16.568	EPSD	COSMIC	9.540	Up-regulation
Atypical_PIKK_ATM_ATM_ST	O96017	CHEK2	Q13315	ATM	S19	S19L	19	Missense	central	0	yes	16.504	0.000	EPSD	COSMIC	9.540	Loss
Atypical_PIKK_ATM_ATM_ST	O96017	CHEK2	Q13315	ATM	T26	V25I	25	Missense	proximal	-1	no	14.091	14.294	EPSD;PhosphoSitePlus	COSMIC	9.540	Up-regulation
Atypical_PIKK_ATM_ATM_ST	O96017	CHEK2	Q13315	ATM	T26	S19L	19	Missense	distal	-7	no	14.091	13.504	EPSD;PhosphoSitePlus	COSMIC	9.540	Down-regulation
Atypical_PIKK_ATM_ATM_ST	O96017	CHEK2	Q13315	ATM	S28	V25I	25	Missense	distal	-3	no	14.052	14.303	EPSD;PhosphoSitePlus	COSMIC	9.540	Up-regulation
Atypical_PIKK_ATM_ATM_ST	O96017	CHEK2	Q13315	ATM	S50	M46T	46	Missense	distal	-4	no	15.257	15.881	EPSD	COSMIC	9.540	Up-regulation
Atypical_PIKK_ATM_ATM_ST	O96017	CHEK2	Q13315	ATM	S50	S52P	52	Missense	proximal	2	no	15.257	14.802	EPSD	COSMIC;GDSC;CCLE	9.540	Down-regulation
Atypical_PIKK_ATM_ATM_ST	O96017	CHEK2	Q13315	ATM	S50	S49C	49	Missense	proximal	-1	no	15.257	15.057	EPSD	COSMIC	9.540	Down-regulation
Atypical_PIKK_ATM_ATM_ST	O96017	CHEK2	Q13315	ATM	S50	S50N	50	Missense	central	0	yes	15.257	0.000	EPSD	COSMIC	9.540	Loss
Atypical_PIKK_ATM_ATM_ST	O96017	CHEK2	Q13315	ATM	T68	Q69R	69	Missense	proximal	1	no	14.453	7.801	EPSD;PhosphoSitePlus	COSMIC	9.540	Loss
Atypical_PIKK_ATM_ATM_ST	O96017	CHEK2	Q13315	ATM	S140	T133K	133	Missense	distal	-7	no	10.517	10.285	EPSD	COSMIC	9.540	Down-regulation
Atypical_PIKK_ATM_ATM_ST	O96017	CHEK2	Q13315	ATM	S140	R137Q	137	Missense	distal	-3	no	10.517	9.742	EPSD	COSMIC	9.540	Down-regulation
Atypical_PIKK_ATM_ATM_ST	O96017	CHEK2	Q13315	ATM	S140	R145L	145	Missense	distal	5	no	10.517	10.516	EPSD	COSMIC	9.540	Down-regulation
Atypical_PIKK_ATM_ATM_ST	O96017	CHEK2	Q13315	ATM	S140	F144L	144	Missense	distal	4	no	10.517	10.031	EPSD	COSMIC	9.540	Down-regulation
Atypical_PIKK_ATM_ATM_ST	O96017	CHEK2	Q13315	ATM	S192	V198L	198	Missense	distal	6	no	10.945	10.913	EPSD	COSMIC	9.540	Down-regulation
Atypical_PIKK_ATM_ATM_ST	O96017	CHEK2	Q13315	ATM	S192	N186H	186	Missense	distal	-6	no	10.945	10.882	EPSD	COSMIC	9.540	Down-regulation
Atypical_PIKK_ATM_ATM_ST	O96017	CHEK2	Q13315	ATM	S192	A190S	190	Missense	proximal	-2	no	10.945	11.133	EPSD	COSMIC	9.540	Up-regulation
Atypical_PIKK_ATM_ATM_ST	O96017	CHEK2	Q13315	ATM	S192	A190V	190	Missense	proximal	-2	no	10.945	10.468	EPSD	COSMIC	9.540	Down-regulation
Atypical_PIKK_ATM_ATM_ST	O96017	CHEK2	Q13315	ATM	S192	S187C	187	Missense	distal	-5	no	10.945	11.038	EPSD	COSMIC	9.540	Up-regulation
Atypical_PIKK_ATM_ATM_ST	O96017	CHEK2	Q13315	ATM	S192	N185Y	185	Missense	distal	-7	no	10.945	10.837	EPSD	COSMIC	9.540	Down-regulation
Atypical_PIKK_ATM_ATM_ST	O96017	CHEK2	Q13315	ATM	S192	E188K	188	Missense	distal	-4	no	10.945	9.973	EPSD	COSMIC	9.540	Down-regulation
Atypical_PIKK_ATM_ATM_ST	O96017	CHEK2	Q13315	ATM	S192	E188D	188	Missense	distal	-4	no	10.945	10.662	EPSD	COSMIC	9.540	Down-regulation
Atypical_PIKK_ATM_ATM_ST	O96017	CHEK2	Q13315	ATM	S192	N196I	196	Missense	distal	4	no	10.945	11.481	EPSD	COSMIC	9.540	Up-regulation
Atypical_PIKK_ATM_ATM_ST	O96017	CHEK2	Q13315	ATM	S357	D361Y	361	Missense	distal	4	no	14.674	14.770	EPSD	COSMIC	9.540	Up-regulation
Atypical_PIKK_ATM_ATM_ST	O96017	CHEK2	Q13315	ATM	S357	E360Q	360	Missense	distal	3	no	14.674	14.933	EPSD	COSMIC	9.540	Up-regulation
Atypical_PIKK_ATM_ATM_ST	O96017	CHEK2	Q13315	ATM	S357	D361E	361	Missense	distal	4	no	14.674	14.169	EPSD	COSMIC	9.540	Down-regulation
Atypical_PIKK_ATM_ATM_ST	O96017	CHEK2	Q13315	ATM	S357	S356L	356	Missense	proximal	-1	no	14.674	14.539	EPSD	COSMIC	9.540	Down-regulation
Atypical_PIKK_ATM_ATM_ST	O96017	CHEK2	Q13315	ATM	S357	L355P	355	Missense	proximal	-2	no	14.674	14.827	EPSD	COSMIC;CCLE	9.540	Up-regulation
Atypical_PIKK_ATM_ATM_ST	O96017	CHEK2	Q13315	ATM	T432	P426L	426	Missense	distal	-6	no	10.889	10.660	EPSD	COSMIC	9.540	Down-regulation
Atypical_PIKK_ATM_ATM_ST	O96017	CHEK2	Q13315	ATM	T432	K437Q	437	Missense	distal	5	no	10.889	10.939	EPSD	COSMIC	9.540	Up-regulation
Atypical_PIKK_ATM_ATM_ST	O96017	CHEK2	Q13315	ATM	S500	K494M	494	Missense	distal	-6	no	11.027	10.895	EPSD	COSMIC	9.540	Down-regulation
Atypical_PIKK_ATM_ATM_ST	O96017	CHEK2	Q13315	ATM	S518	R519Q	519	Missense	proximal	1	no	8.760	15.411	EPSD	COSMIC	9.540	Gain
Atypical_PIKK_ATM_ATM_ST	Q8IY92	SLX4	Q13315	ATM	S115	K121N	121	Missense	distal	6	no	13.628	13.639	EPSD	COSMIC	9.540	Up-regulation
Atypical_PIKK_ATM_ATM_ST	Q8IY92	SLX4	Q13315	ATM	S169	S173F	173	Missense	distal	4	no	9.233	10.061	EPSD	COSMIC	9.540	Gain
Atypical_PIKK_ATM_ATM_ST	Q8IY92	SLX4	Q13315	ATM	S173	R178I	178	Missense	distal	5	no	9.696	9.740	EPSD	COSMIC;GDSC;CCLE	9.540	Up-regulation
Atypical_PIKK_ATM_ATM_ST	Q8IY92	SLX4	Q13315	ATM	S173	P168Q	168	Missense	distal	-5	no	9.696	9.559	EPSD	COSMIC	9.540	Down-regulation
Atypical_PIKK_ATM_ATM_ST	Q8IY92	SLX4	Q13315	ATM	S173	S173F	173	Missense	central	0	yes	9.696	0.000	EPSD	COSMIC	9.540	Loss
Atypical_PIKK_ATM_ATM_ST	Q8IY92	SLX4	Q13315	ATM	S186	Q187H	187	Missense	proximal	1	no	14.902	-0.007	EPSD	COSMIC	9.540	Loss
Atypical_PIKK_ATM_ATM_ST	Q8IY92	SLX4	Q13315	ATM	S186	P190L	190	Missense	distal	4	no	14.902	15.121	EPSD	COSMIC	9.540	Up-regulation
Atypical_PIKK_ATM_ATM_ST	Q8IY92	SLX4	Q13315	ATM	S228	S228L	228	Missense	central	0	yes	9.626	0.000	EPSD	COSMIC;GDSC;CCLE	9.540	Loss
Atypical_PIKK_ATM_ATM_ST	Q8IY92	SLX4	Q13315	ATM	S383	P385T	385	Missense	proximal	2	no	12.279	12.471	EPSD	COSMIC	9.540	Up-regulation
Atypical_PIKK_ATM_ATM_ST	Q8IY92	SLX4	Q13315	ATM	S383	P385S	385	Missense	proximal	2	no	12.279	12.733	EPSD	COSMIC	9.540	Up-regulation
Atypical_PIKK_ATM_ATM_ST	Q8IY92	SLX4	Q13315	ATM	S467	L472S	472	Missense	distal	5	no	11.693	11.529	EPSD	COSMIC;GDSC;CCLE	9.540	Down-regulation
Atypical_PIKK_ATM_ATM_ST	Q8IY92	SLX4	Q13315	ATM	S467	P468L	468	Missense	proximal	1	no	11.693	10.139	EPSD	COSMIC	9.540	Down-regulation
Atypical_PIKK_ATM_ATM_ST	Q8IY92	SLX4	Q13315	ATM	S467	R460H	460	Missense	distal	-7	no	11.693	11.779	EPSD	COSMIC	9.540	Up-regulation
Atypical_PIKK_ATM_ATM_ST	Q8IY92	SLX4	Q13315	ATM	S476	L472S	472	Missense	distal	-4	no	10.448	11.388	EPSD	COSMIC;GDSC;CCLE	9.540	Up-regulation
Atypical_PIKK_ATM_ATM_ST	Q8IY92	SLX4	Q13315	ATM	S492	L491F	491	Missense	proximal	-1	no	10.635	10.344	EPSD	COSMIC	9.540	Down-regulation
Atypical_PIKK_ATM_ATM_ST	Q8IY92	SLX4	Q13315	ATM	T500	T500M	500	Missense	central	0	yes	11.655	0.000	EPSD	COSMIC;GDSC	9.540	Loss
Atypical_PIKK_ATM_ATM_ST	Q8IY92	SLX4	Q13315	ATM	T500	P504H	504	Missense	distal	4	no	11.655	11.650	EPSD	COSMIC;GDSC;CCLE	9.540	Down-regulation
Atypical_PIKK_ATM_ATM_ST	Q8IY92	SLX4	Q13315	ATM	S584	L587F	587	Missense	distal	3	no	9.829	10.128	EPSD	COSMIC	9.540	Up-regulation
Atypical_PIKK_ATM_ATM_ST	Q8IY92	SLX4	Q13315	ATM	S659	G654R	654	Missense	distal	-5	no	14.326	14.348	EPSD	COSMIC	9.540	Up-regulation
Atypical_PIKK_ATM_ATM_ST	Q8IY92	SLX4	Q13315	ATM	S1044	Q1041R	1041	Missense	distal	-3	no	8.902	9.677	EPSD	COSMIC	9.540	Gain
Atypical_PIKK_ATM_ATM_ST	Q8IY92	SLX4	Q13315	ATM	S1066	R1060Q	1060	Missense	distal	-6	no	12.570	12.713	EPSD	COSMIC	9.540	Up-regulation
Atypical_PIKK_ATM_ATM_ST	Q8IY92	SLX4	Q13315	ATM	S1070	G1064R	1064	Missense	distal	-6	no	9.715	9.736	EPSD	COSMIC	9.540	Up-regulation
Atypical_PIKK_ATM_ATM_ST	Q8IY92	SLX4	Q13315	ATM	S1121	Q1128K	1128	Missense	distal	7	no	9.742	9.755	EPSD	COSMIC	9.540	Up-regulation
Atypical_PIKK_ATM_ATM_ST	Q8IY92	SLX4	Q13315	ATM	S1121	Q1128P	1128	Missense	distal	7	no	9.742	9.751	EPSD	COSMIC	9.540	Up-regulation
Atypical_PIKK_ATM_ATM_ST	Q8IY92	SLX4	Q13315	ATM	S1121	S1123P	1123	Missense	proximal	2	no	9.742	9.287	EPSD	COSMIC;GDSC	9.540	Loss
Atypical_PIKK_ATM_ATM_ST	Q8IY92	SLX4	Q13315	ATM	T1127	S1129L	1129	Missense	proximal	2	no	13.533	12.289	EPSD	COSMIC	9.540	Down-regulation
Atypical_PIKK_ATM_ATM_ST	Q8IY92	SLX4	Q13315	ATM	T1127	P1131L	1131	Missense	distal	4	no	13.533	13.752	EPSD	COSMIC;GDSC;CCLE	9.540	Up-regulation
Atypical_PIKK_ATM_ATM_ST	Q8IY92	SLX4	Q13315	ATM	T1127	Q1128K	1128	Missense	proximal	1	no	13.533	6.685	EPSD	COSMIC	9.540	Loss
Atypical_PIKK_ATM_ATM_ST	Q8IY92	SLX4	Q13315	ATM	T1127	Q1128P	1128	Missense	proximal	1	no	13.533	8.731	EPSD	COSMIC	9.540	Loss
Atypical_PIKK_ATM_ATM_ST	Q8IY92	SLX4	Q13315	ATM	T1127	S1123P	1123	Missense	distal	-4	no	13.533	12.864	EPSD	COSMIC;GDSC	9.540	Down-regulation
Atypical_PIKK_ATM_ATM_ST	Q8IY92	SLX4	Q13315	ATM	S1136	S1129L	1129	Missense	distal	-7	no	11.058	10.471	EPSD	COSMIC	9.540	Down-regulation
Atypical_PIKK_ATM_ATM_ST	Q8IY92	SLX4	Q13315	ATM	S1136	P1131L	1131	Missense	distal	-5	no	11.058	11.077	EPSD	COSMIC;GDSC;CCLE	9.540	Up-regulation
Atypical_PIKK_ATM_ATM_ST	Q8IY92	SLX4	Q13315	ATM	S1138	P1131L	1131	Missense	distal	-7	no	14.212	13.861	EPSD;PhosphoSitePlus	COSMIC;GDSC;CCLE	9.540	Down-regulation
Atypical_PIKK_ATM_ATM_ST	Q8IY92	SLX4	Q13315	ATM	S1244	S1249I	1249	Missense	distal	5	no	9.560	9.769	EPSD	COSMIC	9.540	Up-regulation
Atypical_PIKK_ATM_ATM_ST	Q8IY92	SLX4	Q13315	ATM	S1271	L1278F	1278	Missense	distal	7	no	14.329	14.370	EPSD;PhosphoSitePlus	COSMIC	9.540	Up-regulation
Atypical_PIKK_ATM_ATM_ST	Q8IY92	SLX4	Q13315	ATM	S1271	S1277R	1277	Missense	distal	6	no	14.329	14.311	EPSD;PhosphoSitePlus	COSMIC	9.540	Down-regulation
Atypical_PIKK_ATM_ATM_ST	Q8IY92	SLX4	Q13315	ATM	T1273	L1278F	1278	Missense	distal	5	no	10.277	10.418	EPSD	COSMIC	9.540	Up-regulation
Atypical_PIKK_ATM_ATM_ST	Q8IY92	SLX4	Q13315	ATM	T1273	S1277R	1277	Missense	distal	4	no	10.277	10.459	EPSD	COSMIC	9.540	Up-regulation
Atypical_PIKK_ATM_ATM_ST	Q8IY92	SLX4	Q13315	ATM	T1288	G1281R	1281	Missense	distal	-7	no	12.351	12.465	EPSD	COSMIC	9.540	Up-regulation
Atypical_PIKK_ATM_ATM_ST	Q8IY92	SLX4	Q13315	ATM	T1288	A1283V	1283	Missense	distal	-5	no	12.351	12.472	EPSD	COSMIC	9.540	Up-regulation
Atypical_PIKK_ATM_ATM_ST	Q8IY92	SLX4	Q13315	ATM	S1355	A1358G	1358	Missense	distal	3	no	9.791	9.866	EPSD	COSMIC	9.540	Up-regulation
Atypical_PIKK_ATM_ATM_ST	Q8IY92	SLX4	Q13315	ATM	S1355	P1348L	1348	Missense	distal	-7	no	9.791	9.439	EPSD	COSMIC	9.540	Loss
Atypical_PIKK_ATM_ATM_ST	Q8IY92	SLX4	Q13315	ATM	S1453	G1447S	1447	Missense	distal	-6	no	11.360	11.561	EPSD	COSMIC	9.540	Up-regulation
Atypical_PIKK_ATM_ATM_ST	Q8IY92	SLX4	Q13315	ATM	S1453	T1451I	1451	Missense	proximal	-2	no	11.360	10.758	EPSD	COSMIC	9.540	Down-regulation
Atypical_PIKK_ATM_ATM_ST	Q8IY92	SLX4	Q13315	ATM	S1453	S1455N	1455	Missense	proximal	2	no	11.360	10.718	EPSD	COSMIC	9.540	Down-regulation
Atypical_PIKK_ATM_ATM_ST	Q8IY92	SLX4	Q13315	ATM	S1455	T1451I	1451	Missense	distal	-4	no	9.774	9.446	EPSD	COSMIC	9.540	Loss
Atypical_PIKK_ATM_ATM_ST	Q8IY92	SLX4	Q13315	ATM	S1455	S1455N	1455	Missense	central	0	yes	9.774	0.000	EPSD	COSMIC	9.540	Loss
Atypical_PIKK_ATM_ATM_ST	Q8IY92	SLX4	Q13315	ATM	S1608	D1612N	1612	Missense	distal	4	no	9.763	9.682	EPSD	COSMIC	9.540	Down-regulation
Atypical_PIKK_ATM_ATM_ST	Q8IY92	SLX4	Q13315	ATM	S1608	T1605I	1605	Missense	distal	-3	no	9.763	10.500	EPSD	COSMIC	9.540	Up-regulation
Atypical_PIKK_ATM_ATM_ST	Q8IY92	SLX4	Q13315	ATM	S1610	D1612N	1612	Missense	proximal	2	no	9.762	8.740	EPSD	COSMIC	9.540	Loss
Atypical_PIKK_ATM_ATM_ST	Q8IY92	SLX4	Q13315	ATM	S1610	T1605I	1605	Missense	distal	-5	no	9.762	9.965	EPSD	COSMIC	9.540	Up-regulation
Atypical_PIKK_ATM_ATM_ST	Q8IY92	SLX4	Q13315	ATM	S1614	D1612N	1612	Missense	proximal	-2	no	14.582	14.701	EPSD	COSMIC	9.540	Up-regulation
Atypical_PIKK_ATM_ATM_ST	Q8IY92	SLX4	Q13315	ATM	S1617	D1612N	1612	Missense	distal	-5	no	14.115	14.299	EPSD	COSMIC	9.540	Up-regulation
Atypical_PIKK_ATM_ATM_ST	Q8IY92	SLX4	Q13315	ATM	S1631	P1636A	1636	Missense	distal	5	no	13.652	13.518	PhosphoSitePlus;EPSD	COSMIC	9.540	Down-regulation
Atypical_PIKK_ATM_ATM_ST	Q8IY92	SLX4	Q13315	ATM	S1681	P1677L	1677	Missense	distal	-4	no	10.439	10.169	EPSD	COSMIC	9.540	Down-regulation
Atypical_PIKK_ATM_ATM_ST	Q8IY92	SLX4	Q13315	ATM	S1681	P1678S	1678	Missense	distal	-3	no	10.439	10.243	EPSD	COSMIC	9.540	Down-regulation
Atypical_PIKK_ATM_ATM_ST	Q8IY92	SLX4	Q13315	ATM	S1716	S1720F	1720	Missense	distal	4	no	14.699	15.527	EPSD;PhosphoSitePlus	COSMIC	9.540	Up-regulation
Atypical_PIKK_ATM_ATM_ST	Q6UWZ7	ABRAXAS1	Q13315	ATM	T46	G39S	39	Missense	distal	-7	no	9.217	9.729	EPSD	COSMIC	9.540	Gain
Atypical_PIKK_ATM_ATM_ST	Q6UWZ7	ABRAXAS1	Q13315	ATM	S48	K42N	42	Missense	distal	-6	no	15.246	15.243	EPSD	COSMIC	9.540	Down-regulation
Atypical_PIKK_ATM_ATM_ST	Q6UWZ7	ABRAXAS1	Q13315	ATM	S48	S48F	48	Missense	central	0	yes	15.246	0.000	EPSD	COSMIC	9.540	Loss
Atypical_PIKK_ATM_ATM_ST	Q6UWZ7	ABRAXAS1	Q13315	ATM	S48	E54K	54	Missense	distal	6	no	15.246	15.200	EPSD	COSMIC	9.540	Down-regulation
Atypical_PIKK_ATM_ATM_ST	Q6UWZ7	ABRAXAS1	Q13315	ATM	S48	T46A	46	Missense	proximal	-2	no	15.246	15.146	EPSD	COSMIC	9.540	Down-regulation
Atypical_PIKK_ATM_ATM_ST	Q6UWZ7	ABRAXAS1	Q13315	ATM	S48	D52N	52	Missense	distal	4	no	15.246	15.165	EPSD	COSMIC	9.540	Down-regulation
Atypical_PIKK_ATM_ATM_ST	Q6UWZ7	ABRAXAS1	Q13315	ATM	S336	D331G	331	Missense	distal	-5	no	10.832	11.098	EPSD	COSMIC	9.540	Up-regulation
Atypical_PIKK_ATM_ATM_ST	Q6UWZ7	ABRAXAS1	Q13315	ATM	S336	I343S	343	Missense	distal	7	no	10.832	10.801	EPSD	COSMIC	9.540	Down-regulation
Atypical_PIKK_ATM_ATM_ST	Q6UWZ7	ABRAXAS1	Q13315	ATM	S336	E334K	334	Missense	proximal	-2	no	10.832	10.256	EPSD	COSMIC	9.540	Down-regulation
Atypical_PIKK_ATM_ATM_ST	Q6UWZ7	ABRAXAS1	Q13315	ATM	S336	H329N	329	Missense	distal	-7	no	10.832	10.959	EPSD	COSMIC	9.540	Up-regulation
Atypical_PIKK_ATM_ATM_ST	Q6UWZ7	ABRAXAS1	Q13315	ATM	T340	K347N	347	Missense	distal	7	no	11.814	11.806	EPSD	COSMIC	9.540	Down-regulation
Atypical_PIKK_ATM_ATM_ST	Q6UWZ7	ABRAXAS1	Q13315	ATM	T340	I343S	343	Missense	distal	3	no	11.814	11.313	EPSD	COSMIC	9.540	Down-regulation
Atypical_PIKK_ATM_ATM_ST	Q6UWZ7	ABRAXAS1	Q13315	ATM	T340	E334K	334	Missense	distal	-6	no	11.814	11.513	EPSD	COSMIC	9.540	Down-regulation
Atypical_PIKK_ATM_ATM_ST	Q6UWZ7	ABRAXAS1	Q13315	ATM	T365	S370C	370	Missense	distal	5	no	10.332	10.558	EPSD	COSMIC	9.540	Up-regulation
Atypical_PIKK_ATM_ATM_ST	Q6UWZ7	ABRAXAS1	Q13315	ATM	T365	R361W	361	Missense	distal	-4	no	10.332	9.856	EPSD	COSMIC	9.540	Down-regulation
Atypical_PIKK_ATM_ATM_ST	Q6UWZ7	ABRAXAS1	Q13315	ATM	T365	D367N	367	Missense	proximal	2	no	10.332	9.310	EPSD	COSMIC	9.540	Loss
Atypical_PIKK_ATM_ATM_ST	Q6UWZ7	ABRAXAS1	Q13315	ATM	T365	R361Q	361	Missense	distal	-4	no	10.332	10.698	EPSD	COSMIC	9.540	Up-regulation
Atypical_PIKK_ATM_ATM_ST	Q6UWZ7	ABRAXAS1	Q13315	ATM	T365	R369Q	369	Missense	distal	4	no	10.332	10.183	EPSD	COSMIC	9.540	Down-regulation
Atypical_PIKK_ATM_ATM_ST	Q6UWZ7	ABRAXAS1	Q13315	ATM	T365	S360F	360	Missense	distal	-5	no	10.332	10.655	EPSD	COSMIC	9.540	Up-regulation
Atypical_PIKK_ATM_ATM_ST	Q6UWZ7	ABRAXAS1	Q13315	ATM	T365	D364G	364	Missense	proximal	-1	no	10.332	10.195	EPSD	COSMIC	9.540	Down-regulation
Atypical_PIKK_ATM_ATM_ST	Q6UWZ7	ABRAXAS1	Q13315	ATM	S387	E393K	393	Missense	distal	6	no	9.831	9.785	EPSD	COSMIC	9.540	Down-regulation
Atypical_PIKK_ATM_ATM_ST	Q6UWZ7	ABRAXAS1	Q13315	ATM	S387	D380G	380	Missense	distal	-7	no	9.831	9.541	EPSD	COSMIC	9.540	Down-regulation
Atypical_PIKK_ATM_ATM_ST	Q6UWZ7	ABRAXAS1	Q13315	ATM	S387	P388S	388	Missense	proximal	1	no	9.831	2.855	EPSD	COSMIC	9.540	Loss
Atypical_PIKK_ATM_ATM_ST	Q6UWZ7	ABRAXAS1	Q13315	ATM	S387	M385I	385	Missense	proximal	-2	no	9.831	9.579	EPSD	COSMIC	9.540	Down-regulation
Atypical_PIKK_ATM_ATM_ST	Q6UWZ7	ABRAXAS1	Q13315	ATM	S404	R405Q	405	Missense	proximal	1	no	9.908	16.560	EPSD;PhosphoSitePlus	COSMIC	9.540	Up-regulation
Atypical_PIKK_ATM_ATM_ST	Q6UWZ7	ABRAXAS1	Q13315	ATM	S406	R405Q	405	Missense	proximal	-1	no	11.811	12.119	PhosphoSitePlus;EPSD	COSMIC	9.540	Up-regulation
Atypical_PIKK_ATM_ATM_ST	Q9UGP5	POLL	Q13315	ATM	S167	T173A	173	Missense	distal	6	no	10.198	10.214	EPSD	COSMIC	9.540	Up-regulation
Atypical_PIKK_ATM_ATM_ST	Q9UGP5	POLL	Q13315	ATM	S167	T173P	173	Missense	distal	6	no	10.198	10.197	EPSD	COSMIC	9.540	Down-regulation
Atypical_PIKK_ATM_ATM_ST	Q9UGP5	POLL	Q13315	ATM	S167	L162M	162	Missense	distal	-5	no	10.198	10.260	EPSD	COSMIC	9.540	Up-regulation
Atypical_PIKK_ATM_ATM_ST	Q9UGP5	POLL	Q13315	ATM	S177	T173A	173	Missense	distal	-4	no	10.282	10.155	EPSD	COSMIC	9.540	Down-regulation
Atypical_PIKK_ATM_ATM_ST	Q9UGP5	POLL	Q13315	ATM	S177	T173P	173	Missense	distal	-4	no	10.282	9.995	EPSD	COSMIC	9.540	Down-regulation
Atypical_PIKK_ATM_ATM_ST	Q9UGP5	POLL	Q13315	ATM	S177	P175S	175	Missense	proximal	-2	no	10.282	10.518	EPSD	COSMIC	9.540	Up-regulation
Atypical_PIKK_ATM_ATM_ST	Q9UGP5	POLL	Q13315	ATM	T204	A198T	198	Missense	distal	-6	no	12.953	12.904	PhosphoSitePlus	COSMIC	9.540	Down-regulation
Atypical_PIKK_ATM_ATM_ST	Q9UGP5	POLL	Q13315	ATM	T204	S207L	207	Missense	distal	3	no	12.953	13.235	PhosphoSitePlus	COSMIC	9.540	Up-regulation
Atypical_PIKK_ATM_ATM_ST	Q9UGP5	POLL	Q13315	ATM	T204	S199N	199	Missense	distal	-5	no	12.953	12.925	PhosphoSitePlus	COSMIC	9.540	Down-regulation
Atypical_PIKK_ATM_ATM_ST	Q9UGP5	POLL	Q13315	ATM	S246	H252D	252	Missense	distal	6	no	14.815	14.826	EPSD	COSMIC	9.540	Up-regulation
Atypical_PIKK_ATM_ATM_ST	Q9UGP5	POLL	Q13315	ATM	S246	A249V	249	Missense	distal	3	no	14.815	15.103	EPSD	COSMIC;CCLE	9.540	Up-regulation
Atypical_PIKK_ATM_ATM_ST	Q9UGP5	POLL	Q13315	ATM	S246	N251S	251	Missense	distal	5	no	14.815	14.840	EPSD	COSMIC	9.540	Up-regulation
Atypical_PIKK_ATM_ATM_ST	Q9UGP5	POLL	Q13315	ATM	S526	A520S	520	Missense	distal	-6	no	9.797	9.817	EPSD	COSMIC	9.540	Up-regulation
Atypical_PIKK_ATM_ATM_ST	P60484	PTEN	Q13315	ATM	S113	L108R	108	Missense	distal	-5	no	12.108	12.161	EPSD;PhosphoSitePlus	COSMIC;GDSC;CCLE	9.540	Up-regulation
Atypical_PIKK_ATM_ATM_ST	P60484	PTEN	Q13315	ATM	S113	L108H	108	Missense	distal	-5	no	12.108	12.133	EPSD;PhosphoSitePlus	COSMIC	9.540	Up-regulation
Atypical_PIKK_ATM_ATM_ST	P60484	PTEN	Q13315	ATM	S113	Q110R	110	Missense	distal	-3	no	12.108	12.882	EPSD;PhosphoSitePlus	COSMIC	9.540	Up-regulation
Atypical_PIKK_ATM_ATM_ST	P60484	PTEN	Q13315	ATM	S113	L112Q	112	Missense	proximal	-1	no	12.108	12.176	EPSD;PhosphoSitePlus	COSMIC;GDSC;CCLE	9.540	Up-regulation
Atypical_PIKK_ATM_ATM_ST	P60484	PTEN	Q13315	ATM	S113	A120T	120	Missense	distal	7	no	12.108	12.093	EPSD;PhosphoSitePlus	COSMIC	9.540	Down-regulation
Atypical_PIKK_ATM_ATM_ST	P60484	PTEN	Q13315	ATM	S113	E106G	106	Missense	distal	-7	no	12.108	11.239	EPSD;PhosphoSitePlus	COSMIC;GDSC;CCLE	9.540	Down-regulation
Atypical_PIKK_ATM_ATM_ST	P60484	PTEN	Q13315	ATM	S113	D116G	116	Missense	distal	3	no	12.108	12.055	EPSD;PhosphoSitePlus	COSMIC	9.540	Down-regulation
Atypical_PIKK_ATM_ATM_ST	P60484	PTEN	Q13315	ATM	S113	H118L	118	Missense	distal	5	no	12.108	12.132	EPSD;PhosphoSitePlus	COSMIC	9.540	Up-regulation
Atypical_PIKK_ATM_ATM_ST	P60484	PTEN	Q13315	ATM	S113	D107V	107	Missense	distal	-6	no	12.108	11.878	EPSD;PhosphoSitePlus	COSMIC	9.540	Down-regulation
Atypical_PIKK_ATM_ATM_ST	P60484	PTEN	Q13315	ATM	S113	N117S	117	Missense	distal	4	no	12.108	11.980	EPSD;PhosphoSitePlus	COSMIC	9.540	Down-regulation
Atypical_PIKK_ATM_ATM_ST	P60484	PTEN	Q13315	ATM	S113	W111G	111	Missense	proximal	-2	no	12.108	12.159	EPSD;PhosphoSitePlus	COSMIC	9.540	Up-regulation
Atypical_PIKK_ATM_ATM_ST	P60484	PTEN	Q13315	ATM	S113	D107A	107	Missense	distal	-6	no	12.108	12.114	EPSD;PhosphoSitePlus	COSMIC	9.540	Up-regulation
Atypical_PIKK_ATM_ATM_ST	P60484	PTEN	Q13315	ATM	S113	D115N	115	Missense	proximal	2	no	12.108	11.086	EPSD;PhosphoSitePlus	COSMIC	9.540	Down-regulation
Atypical_PIKK_ATM_ATM_ST	P60484	PTEN	Q13315	ATM	S113	V119D	119	Missense	distal	6	no	12.108	12.109	EPSD;PhosphoSitePlus	COSMIC	9.540	Up-regulation
Atypical_PIKK_ATM_ATM_ST	P60484	PTEN	Q13315	ATM	S113	V119A	119	Missense	distal	6	no	12.108	12.138	EPSD;PhosphoSitePlus	COSMIC	9.540	Up-regulation
Atypical_PIKK_ATM_ATM_ST	P60484	PTEN	Q13315	ATM	S113	D107E	107	Missense	distal	-6	no	12.108	12.322	EPSD;PhosphoSitePlus	COSMIC	9.540	Up-regulation
Atypical_PIKK_ATM_ATM_ST	P60484	PTEN	Q13315	ATM	S113	W111S	111	Missense	proximal	-2	no	12.108	12.601	EPSD;PhosphoSitePlus	COSMIC	9.540	Up-regulation
Atypical_PIKK_ATM_ATM_ST	P60484	PTEN	Q13315	ATM	S113	D109Y	109	Missense	distal	-4	no	12.108	11.011	EPSD;PhosphoSitePlus	COSMIC	9.540	Down-regulation
Atypical_PIKK_ATM_ATM_ST	P60484	PTEN	Q13315	ATM	S113	S113R	113	Missense	central	0	yes	12.108	0.000	EPSD;PhosphoSitePlus	COSMIC	9.540	Loss
Atypical_PIKK_ATM_ATM_ST	P60484	PTEN	Q13315	ATM	S170	Y176F	176	Missense	distal	6	no	12.740	12.705	EPSD	COSMIC	9.540	Down-regulation
Atypical_PIKK_ATM_ATM_ST	P60484	PTEN	Q13315	ATM	S170	G165V	165	Missense	distal	-5	no	12.740	12.799	EPSD	COSMIC	9.540	Up-regulation
Atypical_PIKK_ATM_ATM_ST	P60484	PTEN	Q13315	ATM	S170	Y174D	174	Missense	distal	4	no	12.740	12.645	EPSD	COSMIC	9.540	Down-regulation
Atypical_PIKK_ATM_ATM_ST	P60484	PTEN	Q13315	ATM	S170	V166E	166	Missense	distal	-4	no	12.740	14.008	EPSD	COSMIC	9.540	Up-regulation
Atypical_PIKK_ATM_ATM_ST	P60484	PTEN	Q13315	ATM	S170	Y174N	174	Missense	distal	4	no	12.740	12.564	EPSD	COSMIC	9.540	Down-regulation
Atypical_PIKK_ATM_ATM_ST	P60484	PTEN	Q13315	ATM	S170	V166I	166	Missense	distal	-4	no	12.740	13.018	EPSD	COSMIC	9.540	Up-regulation
Atypical_PIKK_ATM_ATM_ST	P60484	PTEN	Q13315	ATM	S170	K164R	164	Missense	distal	-6	no	12.740	12.673	EPSD	COSMIC	9.540	Down-regulation
Atypical_PIKK_ATM_ATM_ST	P60484	PTEN	Q13315	ATM	S170	R172W	172	Missense	proximal	2	no	12.740	12.420	EPSD	COSMIC	9.540	Down-regulation
Atypical_PIKK_ATM_ATM_ST	P60484	PTEN	Q13315	ATM	S170	R173P	173	Missense	distal	3	no	12.740	12.706	EPSD	COSMIC;GDSC;CCLE	9.540	Down-regulation
Atypical_PIKK_ATM_ATM_ST	P60484	PTEN	Q13315	ATM	S170	P169S	169	Missense	proximal	-1	no	12.740	13.032	EPSD	COSMIC	9.540	Up-regulation
Atypical_PIKK_ATM_ATM_ST	P60484	PTEN	Q13315	ATM	S170	V175M	175	Missense	distal	5	no	12.740	12.713	EPSD	COSMIC	9.540	Down-regulation
Atypical_PIKK_ATM_ATM_ST	P60484	PTEN	Q13315	ATM	S170	T167I	167	Missense	distal	-3	no	12.740	13.477	EPSD	COSMIC	9.540	Up-regulation
Atypical_PIKK_ATM_ATM_ST	P60484	PTEN	Q13315	ATM	S170	Y177H	177	Missense	distal	7	no	12.740	12.735	EPSD	COSMIC	9.540	Down-regulation
Atypical_PIKK_ATM_ATM_ST	P60484	PTEN	Q13315	ATM	S170	Q171P	171	Missense	proximal	1	no	12.740	7.938	EPSD	COSMIC	9.540	Loss
Atypical_PIKK_ATM_ATM_ST	P60484	PTEN	Q13315	ATM	S170	P169H	169	Missense	proximal	-1	no	12.740	12.828	EPSD	COSMIC	9.540	Up-regulation
Atypical_PIKK_ATM_ATM_ST	P60484	PTEN	Q13315	ATM	S170	I168F	168	Missense	proximal	-2	no	12.740	12.529	EPSD	COSMIC	9.540	Down-regulation
Atypical_PIKK_ATM_ATM_ST	P60484	PTEN	Q13315	ATM	S170	V166G	166	Missense	distal	-4	no	12.740	12.941	EPSD	COSMIC	9.540	Up-regulation
Atypical_PIKK_ATM_ATM_ST	P60484	PTEN	Q13315	ATM	S170	P169L	169	Missense	proximal	-1	no	12.740	12.897	EPSD	COSMIC	9.540	Up-regulation
Atypical_PIKK_ATM_ATM_ST	P60484	PTEN	Q13315	ATM	S170	V166A	166	Missense	distal	-4	no	12.740	13.219	EPSD	COSMIC	9.540	Up-regulation
Atypical_PIKK_ATM_ATM_ST	P60484	PTEN	Q13315	ATM	S170	Y176C	176	Missense	distal	6	no	12.740	12.709	EPSD	COSMIC	9.540	Down-regulation
Atypical_PIKK_ATM_ATM_ST	P60484	PTEN	Q13315	ATM	S170	T167P	167	Missense	distal	-3	no	12.740	13.004	EPSD	COSMIC	9.540	Up-regulation
Atypical_PIKK_ATM_ATM_ST	P60484	PTEN	Q13315	ATM	S170	V175A	175	Missense	distal	5	no	12.740	12.576	EPSD	COSMIC	9.540	Down-regulation
Atypical_PIKK_ATM_ATM_ST	P60484	PTEN	Q13315	ATM	S170	Y174C	174	Missense	distal	4	no	12.740	12.946	EPSD	COSMIC	9.540	Up-regulation
Atypical_PIKK_ATM_ATM_ST	P60484	PTEN	Q13315	ATM	S170	Q171H	171	Missense	proximal	1	no	12.740	-2.169	EPSD	COSMIC	9.540	Loss
Atypical_PIKK_ATM_ATM_ST	P60484	PTEN	Q13315	ATM	S170	R173S	173	Missense	distal	3	no	12.740	12.554	EPSD	COSMIC	9.540	Down-regulation
Atypical_PIKK_ATM_ATM_ST	P60484	PTEN	Q13315	ATM	S170	Y174H	174	Missense	distal	4	no	12.740	12.554	EPSD	COSMIC	9.540	Down-regulation
Atypical_PIKK_ATM_ATM_ST	P60484	PTEN	Q13315	ATM	S170	V166L	166	Missense	distal	-4	no	12.740	12.790	EPSD	COSMIC	9.540	Up-regulation
Atypical_PIKK_ATM_ATM_ST	P60484	PTEN	Q13315	ATM	S338	N334D	334	Missense	distal	-4	no	9.307	10.231	EPSD	COSMIC	9.540	Gain
Atypical_PIKK_ATM_ATM_ST	P60484	PTEN	Q13315	ATM	S338	F337L	337	Missense	proximal	-1	no	9.307	9.598	EPSD	COSMIC	9.540	Gain
Atypical_PIKK_ATM_ATM_ST	P60484	PTEN	Q13315	ATM	S338	N334S	334	Missense	distal	-4	no	9.307	10.235	EPSD	COSMIC	9.540	Gain
Atypical_PIKK_ATM_ATM_ST	P60484	PTEN	Q13315	ATM	T366	V369G	369	Missense	distal	3	no	12.659	12.446	EPSD	COSMIC	9.540	Down-regulation
Atypical_PIKK_ATM_ATM_ST	P60484	PTEN	Q13315	ATM	T366	V365I	365	Missense	proximal	-1	no	12.659	12.862	EPSD	COSMIC	9.540	Up-regulation
Atypical_PIKK_ATM_ATM_ST	P60484	PTEN	Q13315	ATM	T366	S364C	364	Missense	proximal	-2	no	12.659	12.197	EPSD	COSMIC	9.540	Down-regulation
Atypical_PIKK_ATM_ATM_ST	P60484	PTEN	Q13315	ATM	T366	S361N	361	Missense	distal	-5	no	12.659	12.632	EPSD	COSMIC	9.540	Down-regulation
Atypical_PIKK_ATM_ATM_ST	P60484	PTEN	Q13315	ATM	S370	V369G	369	Missense	proximal	-1	no	10.559	10.791	EPSD	COSMIC	9.540	Up-regulation
Atypical_PIKK_ATM_ATM_ST	P60484	PTEN	Q13315	ATM	S370	D375N	375	Missense	distal	5	no	10.559	10.447	EPSD	COSMIC	9.540	Down-regulation
Atypical_PIKK_ATM_ATM_ST	P60484	PTEN	Q13315	ATM	S370	V365I	365	Missense	distal	-5	no	10.559	10.560	EPSD	COSMIC	9.540	Up-regulation
Atypical_PIKK_ATM_ATM_ST	P60484	PTEN	Q13315	ATM	S370	S364C	364	Missense	distal	-6	no	10.559	10.179	EPSD	COSMIC	9.540	Down-regulation
Atypical_PIKK_ATM_ATM_ST	P60484	PTEN	Q13315	ATM	T398	H397Y	397	Missense	proximal	-1	no	15.262	15.417	PhosphoSitePlus;EPSD	COSMIC	9.540	Up-regulation
Atypical_PIKK_ATM_ATM_ST	P60484	PTEN	Q13315	ATM	T398	Q399H	399	Missense	proximal	1	no	15.262	0.353	PhosphoSitePlus;EPSD	COSMIC	9.540	Loss
Atypical_PIKK_ATM_ATM_ST	P60484	PTEN	Q13315	ATM	T398	T401I	401	Missense	distal	3	no	15.262	15.683	PhosphoSitePlus;EPSD	COSMIC	9.540	Up-regulation
Atypical_PIKK_ATM_ATM_ST	P23025	XPA	Q13315	ATM	S196	A199V	199	Missense	distal	3	no	15.823	16.111	PhosphoSitePlus;EPSD	COSMIC	9.540	Up-regulation
Atypical_PIKK_ATM_ATM_ST	P23025	XPA	Q13315	ATM	S196	E202K	202	Missense	distal	6	no	15.823	15.777	PhosphoSitePlus;EPSD	COSMIC	9.540	Down-regulation
Atypical_PIKK_ATM_ATM_ST	P23025	XPA	Q13315	ATM	S196	Q197R	197	Missense	proximal	1	no	15.823	9.171	PhosphoSitePlus;EPSD	COSMIC	9.540	Loss
Atypical_PIKK_ATM_ATM_ST	P16220	CREB1	Q13315	ATM	T100	S103N	103	Missense	distal	3	no	12.790	12.990	EPSD;PhosphoSitePlus	COSMIC	9.540	Up-regulation
Atypical_PIKK_ATM_ATM_ST	P16220	CREB1	Q13315	ATM	T100	R95I	95	Missense	distal	-5	no	12.790	12.828	EPSD;PhosphoSitePlus	COSMIC	9.540	Up-regulation
Atypical_PIKK_ATM_ATM_ST	P16220	CREB1	Q13315	ATM	T100	I102M	102	Missense	proximal	2	no	12.790	12.417	EPSD;PhosphoSitePlus	COSMIC	9.540	Down-regulation
Atypical_PIKK_ATM_ATM_ST	P16220	CREB1	Q13315	ATM	S111	S117N	117	Missense	distal	6	no	15.623	15.613	EPSD;PhosphoSitePlus	COSMIC	9.540	Down-regulation
Atypical_PIKK_ATM_ATM_ST	P16220	CREB1	Q13315	ATM	S111	V118L	118	Missense	distal	7	no	15.623	15.594	EPSD;PhosphoSitePlus	COSMIC	9.540	Down-regulation
Atypical_PIKK_ATM_ATM_ST	P16220	CREB1	Q13315	ATM	S111	E109K	109	Missense	proximal	-2	no	15.623	15.048	EPSD;PhosphoSitePlus	COSMIC	9.540	Down-regulation
Atypical_PIKK_ATM_ATM_ST	P16220	CREB1	Q13315	ATM	S111	V118I	118	Missense	distal	7	no	15.623	15.606	EPSD;PhosphoSitePlus	COSMIC	9.540	Down-regulation
Atypical_PIKK_ATM_ATM_ST	P16220	CREB1	Q13315	ATM	S117	V118L	118	Missense	proximal	1	no	3.415	10.053	EPSD	COSMIC	9.540	Gain
Atypical_PIKK_ATM_ATM_ST	P16220	CREB1	Q13315	ATM	S121	S117N	117	Missense	distal	-4	no	14.409	13.481	EPSD;PhosphoSitePlus	COSMIC	9.540	Down-regulation
Atypical_PIKK_ATM_ATM_ST	P16220	CREB1	Q13315	ATM	S121	R124Q	124	Missense	distal	3	no	14.409	14.307	EPSD;PhosphoSitePlus	COSMIC	9.540	Down-regulation
Atypical_PIKK_ATM_ATM_ST	P16220	CREB1	Q13315	ATM	S121	V118L	118	Missense	distal	-3	no	14.409	14.200	EPSD;PhosphoSitePlus	COSMIC	9.540	Down-regulation
Atypical_PIKK_ATM_ATM_ST	P16220	CREB1	Q13315	ATM	S121	R125T	125	Missense	distal	4	no	14.409	14.315	EPSD;PhosphoSitePlus	COSMIC	9.540	Down-regulation
Atypical_PIKK_ATM_ATM_ST	P16220	CREB1	Q13315	ATM	S121	L128R	128	Missense	distal	7	no	14.409	14.425	EPSD;PhosphoSitePlus	COSMIC	9.540	Up-regulation
Atypical_PIKK_ATM_ATM_ST	P16220	CREB1	Q13315	ATM	S121	V118I	118	Missense	distal	-3	no	14.409	14.660	EPSD;PhosphoSitePlus	COSMIC	9.540	Up-regulation
Atypical_PIKK_ATM_ATM_ST	P16220	CREB1	Q13315	ATM	S133	L128R	128	Missense	distal	-5	no	11.625	11.678	PhosphoSitePlus;EPSD	COSMIC	9.540	Up-regulation
Atypical_PIKK_ATM_ATM_ST	P16220	CREB1	Q13315	ATM	T276	A269T	269	Missense	distal	-7	no	10.968	10.984	EPSD	COSMIC	9.540	Up-regulation
Atypical_PIKK_ATM_ATM_ST	P35637	FUS	Q13315	ATM	T11	G15R	15	Missense	distal	4	no	11.965	12.018	EPSD	COSMIC	9.540	Up-regulation
Atypical_PIKK_ATM_ATM_ST	P35637	FUS	Q13315	ATM	T19	G15R	15	Missense	distal	-4	no	13.209	13.187	EPSD	COSMIC	9.540	Down-regulation
Atypical_PIKK_ATM_ATM_ST	P35637	FUS	Q13315	ATM	S61	G67E	67	Missense	distal	6	no	15.640	15.683	EPSD	COSMIC	9.540	Up-regulation
Atypical_PIKK_ATM_ATM_ST	P35637	FUS	Q13315	ATM	T68	G67E	67	Missense	proximal	-1	no	13.396	13.798	EPSD	COSMIC	9.540	Up-regulation
Atypical_PIKK_ATM_ATM_ST	P35637	FUS	Q13315	ATM	T68	Q69E	69	Missense	proximal	1	no	13.396	7.499	EPSD	COSMIC	9.540	Loss
Atypical_PIKK_ATM_ATM_ST	P35637	FUS	Q13315	ATM	S84	Q85H	85	Missense	proximal	1	no	16.268	1.359	EPSD	COSMIC	9.540	Loss
Atypical_PIKK_ATM_ATM_ST	P35637	FUS	Q13315	ATM	S84	S87T	87	Missense	distal	3	no	16.268	16.349	EPSD	COSMIC	9.540	Up-regulation
Atypical_PIKK_ATM_ATM_ST	P35637	FUS	Q13315	ATM	S87	G92R	92	Missense	distal	5	no	13.480	13.468	EPSD	COSMIC	9.540	Down-regulation
Atypical_PIKK_ATM_ATM_ST	P35637	FUS	Q13315	ATM	S87	Q85H	85	Missense	proximal	-2	no	13.480	13.177	EPSD	COSMIC	9.540	Down-regulation
Atypical_PIKK_ATM_ATM_ST	P35637	FUS	Q13315	ATM	S117	S119R	119	Missense	proximal	2	no	15.378	14.380	EPSD	COSMIC	9.540	Down-regulation
Atypical_PIKK_ATM_ATM_ST	P35637	FUS	Q13315	ATM	S131	G137A	137	Missense	distal	6	no	14.789	14.814	EPSD	COSMIC	9.540	Up-regulation
Atypical_PIKK_ATM_ATM_ST	P35637	FUS	Q13315	ATM	S131	G128E	128	Missense	distal	-3	no	14.789	14.352	EPSD	COSMIC	9.540	Down-regulation
Atypical_PIKK_ATM_ATM_ST	P35637	FUS	Q13315	ATM	S131	G138A	138	Missense	distal	7	no	14.789	14.779	EPSD	COSMIC	9.540	Down-regulation
Atypical_PIKK_ATM_ATM_ST	P35637	FUS	Q13315	ATM	S277	D270V	270	Missense	distal	-7	no	10.345	10.087	EPSD	COSMIC	9.540	Down-regulation
Atypical_PIKK_ATM_ATM_ST	P35637	FUS	Q13315	ATM	S277	R274C	274	Missense	distal	-3	no	10.345	9.773	EPSD	COSMIC	9.540	Down-regulation
Atypical_PIKK_ATM_ATM_ST	P35637	FUS	Q13315	ATM	S277	D280E	280	Missense	distal	3	no	10.345	9.986	EPSD	COSMIC	9.540	Down-regulation
Atypical_PIKK_ATM_ATM_ST	P35637	FUS	Q13315	ATM	S282	D280E	280	Missense	proximal	-2	no	10.165	10.644	EPSD	COSMIC	9.540	Up-regulation
Atypical_PIKK_ATM_ATM_ST	Q7Z6Z7	HUWE1	Q13315	ATM	T485	R481K	481	Missense	distal	-4	no	14.849	14.966	EPSD	COSMIC;GDSC;CCLE	9.540	Up-regulation
Atypical_PIKK_ATM_ATM_ST	Q7Z6Z7	HUWE1	Q13315	ATM	S636	L634F	634	Missense	proximal	-2	no	13.376	12.866	EPSD	COSMIC	9.540	Down-regulation
Atypical_PIKK_ATM_ATM_ST	Q7Z6Z7	HUWE1	Q13315	ATM	S636	P637L	637	Missense	proximal	1	no	13.376	11.822	EPSD	COSMIC	9.540	Down-regulation
Atypical_PIKK_ATM_ATM_ST	Q7Z6Z7	HUWE1	Q13315	ATM	S854	R860H	860	Missense	distal	6	no	10.174	10.159	EPSD	COSMIC;GDSC;CCLE	9.540	Down-regulation
Atypical_PIKK_ATM_ATM_ST	Q7Z6Z7	HUWE1	Q13315	ATM	S854	L852I	852	Missense	proximal	-2	no	10.174	9.874	EPSD	COSMIC;GDSC;CCLE	9.540	Down-regulation
Atypical_PIKK_ATM_ATM_ST	Q7Z6Z7	HUWE1	Q13315	ATM	S854	H859N	859	Missense	distal	5	no	10.174	10.009	EPSD	COSMIC	9.540	Down-regulation
Atypical_PIKK_ATM_ATM_ST	Q7Z6Z7	HUWE1	Q13315	ATM	S927	I920V	920	Missense	distal	-7	no	14.403	14.587	EPSD;PhosphoSitePlus	COSMIC	9.540	Up-regulation
Atypical_PIKK_ATM_ATM_ST	Q7Z6Z7	HUWE1	Q13315	ATM	S1218	S1221T	1221	Missense	distal	3	no	10.342	10.423	EPSD	COSMIC	9.540	Up-regulation
Atypical_PIKK_ATM_ATM_ST	Q7Z6Z7	HUWE1	Q13315	ATM	S1370	R1365W	1365	Missense	distal	-5	no	10.535	10.701	EPSD	COSMIC	9.540	Up-regulation
Atypical_PIKK_ATM_ATM_ST	Q7Z6Z7	HUWE1	Q13315	ATM	S1707	R1714C	1714	Missense	distal	7	no	9.888	9.906	EPSD	COSMIC	9.540	Up-regulation
Atypical_PIKK_ATM_ATM_ST	Q7Z6Z7	HUWE1	Q13315	ATM	S1736	L1737M	1737	Missense	proximal	1	no	9.702	6.245	EPSD	COSMIC	9.540	Loss
Atypical_PIKK_ATM_ATM_ST	Q7Z6Z7	HUWE1	Q13315	ATM	T2003	D2002V	2002	Missense	proximal	-1	no	15.824	15.454	EPSD	COSMIC;GDSC;CCLE	9.540	Down-regulation
Atypical_PIKK_ATM_ATM_ST	Q7Z6Z7	HUWE1	Q13315	ATM	S2011	A2016T	2016	Missense	distal	5	no	13.768	13.703	EPSD	COSMIC	9.540	Down-regulation
Atypical_PIKK_ATM_ATM_ST	Q7Z6Z7	HUWE1	Q13315	ATM	S2011	G2018V	2018	Missense	distal	7	no	13.768	13.775	EPSD	COSMIC	9.540	Up-regulation
Atypical_PIKK_ATM_ATM_ST	Q7Z6Z7	HUWE1	Q13315	ATM	S2011	G2018W	2018	Missense	distal	7	no	13.768	13.787	EPSD	COSMIC	9.540	Up-regulation
Atypical_PIKK_ATM_ATM_ST	Q7Z6Z7	HUWE1	Q13315	ATM	S2052	E2047K	2047	Missense	distal	-5	no	9.649	9.731	EPSD	COSMIC	9.540	Up-regulation
Atypical_PIKK_ATM_ATM_ST	Q7Z6Z7	HUWE1	Q13315	ATM	S2052	K2046E	2046	Missense	distal	-6	no	9.649	9.950	EPSD	COSMIC	9.540	Up-regulation
Atypical_PIKK_ATM_ATM_ST	Q7Z6Z7	HUWE1	Q13315	ATM	S2052	R2050W	2050	Missense	proximal	-2	no	9.649	9.598	EPSD	COSMIC	9.540	Down-regulation
Atypical_PIKK_ATM_ATM_ST	Q7Z6Z7	HUWE1	Q13315	ATM	S2339	E2341K	2341	Missense	proximal	2	no	16.456	15.125	EPSD;PhosphoSitePlus	COSMIC	9.540	Down-regulation
Atypical_PIKK_ATM_ATM_ST	Q7Z6Z7	HUWE1	Q13315	ATM	S2377	E2376K	2376	Missense	proximal	-1	no	15.651	15.248	EPSD	COSMIC	9.540	Down-regulation
Atypical_PIKK_ATM_ATM_ST	Q7Z6Z7	HUWE1	Q13315	ATM	S2391	A2398T	2398	Missense	distal	7	no	13.767	13.752	EPSD	COSMIC	9.540	Down-regulation
Atypical_PIKK_ATM_ATM_ST	Q7Z6Z7	HUWE1	Q13315	ATM	S2391	Q2392K	2392	Missense	proximal	1	no	13.767	6.918	EPSD	COSMIC	9.540	Loss
Atypical_PIKK_ATM_ATM_ST	Q7Z6Z7	HUWE1	Q13315	ATM	S2477	R2481Q	2481	Missense	distal	4	no	12.054	11.905	EPSD	COSMIC	9.540	Down-regulation
Atypical_PIKK_ATM_ATM_ST	Q7Z6Z7	HUWE1	Q13315	ATM	S2508	P2506S	2506	Missense	proximal	-2	no	11.610	11.847	EPSD	COSMIC	9.540	Up-regulation
Atypical_PIKK_ATM_ATM_ST	Q7Z6Z7	HUWE1	Q13315	ATM	T2540	R2538L	2538	Missense	proximal	-2	no	12.010	12.063	EPSD	COSMIC	9.540	Up-regulation
Atypical_PIKK_ATM_ATM_ST	Q7Z6Z7	HUWE1	Q13315	ATM	T2540	G2544R	2544	Missense	distal	4	no	12.010	12.063	EPSD	COSMIC;GDSC;CCLE	9.540	Up-regulation
Atypical_PIKK_ATM_ATM_ST	Q7Z6Z7	HUWE1	Q13315	ATM	T2540	L2539H	2539	Missense	proximal	-1	no	12.010	11.941	EPSD	COSMIC	9.540	Down-regulation
Atypical_PIKK_ATM_ATM_ST	Q7Z6Z7	HUWE1	Q13315	ATM	T2540	T2540P	2540	Missense	central	0	yes	12.010	0.000	EPSD	COSMIC	9.540	Loss
Atypical_PIKK_ATM_ATM_ST	Q7Z6Z7	HUWE1	Q13315	ATM	S2546	G2544R	2544	Missense	proximal	-2	no	12.023	12.022	EPSD	COSMIC;GDSC;CCLE	9.540	Down-regulation
Atypical_PIKK_ATM_ATM_ST	Q7Z6Z7	HUWE1	Q13315	ATM	S2546	L2539H	2539	Missense	distal	-7	no	12.023	12.297	EPSD	COSMIC	9.540	Up-regulation
Atypical_PIKK_ATM_ATM_ST	Q7Z6Z7	HUWE1	Q13315	ATM	S2546	T2540P	2540	Missense	distal	-6	no	12.023	12.033	EPSD	COSMIC	9.540	Up-regulation
Atypical_PIKK_ATM_ATM_ST	Q7Z6Z7	HUWE1	Q13315	ATM	T2821	L2825R	2825	Missense	distal	4	no	13.010	12.851	EPSD	COSMIC	9.540	Down-regulation
Atypical_PIKK_ATM_ATM_ST	Q7Z6Z7	HUWE1	Q13315	ATM	T2821	P2827Q	2827	Missense	distal	6	no	13.010	12.999	EPSD	COSMIC	9.540	Down-regulation
Atypical_PIKK_ATM_ATM_ST	Q7Z6Z7	HUWE1	Q13315	ATM	T2821	S2826F	2826	Missense	distal	5	no	13.010	13.316	EPSD	COSMIC	9.540	Up-regulation
Atypical_PIKK_ATM_ATM_ST	Q7Z6Z7	HUWE1	Q13315	ATM	T2821	S2815N	2815	Missense	distal	-6	no	13.010	12.894	EPSD	COSMIC	9.540	Down-regulation
Atypical_PIKK_ATM_ATM_ST	Q7Z6Z7	HUWE1	Q13315	ATM	S2826	S2833Y	2833	Missense	distal	7	no	9.681	9.715	EPSD	COSMIC	9.540	Up-regulation
Atypical_PIKK_ATM_ATM_ST	Q7Z6Z7	HUWE1	Q13315	ATM	S2826	L2825R	2825	Missense	proximal	-1	no	9.681	9.442	EPSD	COSMIC	9.540	Loss
Atypical_PIKK_ATM_ATM_ST	Q7Z6Z7	HUWE1	Q13315	ATM	S2826	P2827Q	2827	Missense	proximal	1	no	9.681	14.483	EPSD	COSMIC	9.540	Up-regulation
Atypical_PIKK_ATM_ATM_ST	Q7Z6Z7	HUWE1	Q13315	ATM	S2826	P2829S	2829	Missense	distal	3	no	9.681	9.529	EPSD	COSMIC	9.540	Loss
Atypical_PIKK_ATM_ATM_ST	Q7Z6Z7	HUWE1	Q13315	ATM	S2826	S2826F	2826	Missense	central	0	yes	9.681	0.000	EPSD	COSMIC	9.540	Loss
Atypical_PIKK_ATM_ATM_ST	Q7Z6Z7	HUWE1	Q13315	ATM	S2826	P2829A	2829	Missense	distal	3	no	9.681	9.585	EPSD	COSMIC	9.540	Down-regulation
Atypical_PIKK_ATM_ATM_ST	Q7Z6Z7	HUWE1	Q13315	ATM	S2835	P2836Q	2836	Missense	proximal	1	no	9.475	14.276	EPSD	COSMIC	9.540	Gain
Atypical_PIKK_ATM_ATM_ST	Q7Z6Z7	HUWE1	Q13315	ATM	S2850	A2844S	2844	Missense	distal	-6	no	12.588	12.609	EPSD	COSMIC	9.540	Up-regulation
Atypical_PIKK_ATM_ATM_ST	Q7Z6Z7	HUWE1	Q13315	ATM	S2850	V2848A	2848	Missense	proximal	-2	no	12.588	13.065	EPSD	COSMIC	9.540	Up-regulation
Atypical_PIKK_ATM_ATM_ST	Q7Z6Z7	HUWE1	Q13315	ATM	S2923	D2930H	2930	Missense	distal	7	no	10.474	10.494	EPSD	COSMIC	9.540	Up-regulation
Atypical_PIKK_ATM_ATM_ST	Q7Z6Z7	HUWE1	Q13315	ATM	S2923	S2918F	2918	Missense	distal	-5	no	10.474	10.797	EPSD	COSMIC	9.540	Up-regulation
Atypical_PIKK_ATM_ATM_ST	Q7Z6Z7	HUWE1	Q13315	ATM	S2923	R2929T	2929	Missense	distal	6	no	10.474	10.482	EPSD	COSMIC	9.540	Up-regulation
Atypical_PIKK_ATM_ATM_ST	Q7Z6Z7	HUWE1	Q13315	ATM	S2953	P2949L	2949	Missense	distal	-4	no	12.804	12.534	EPSD	COSMIC	9.540	Down-regulation
Atypical_PIKK_ATM_ATM_ST	Q7Z6Z7	HUWE1	Q13315	ATM	S3052	Q3048H	3048	Missense	distal	-4	no	9.943	9.708	EPSD	COSMIC	9.540	Down-regulation
Atypical_PIKK_ATM_ATM_ST	Q7Z6Z7	HUWE1	Q13315	ATM	S3127	P3128L	3128	Missense	proximal	1	no	9.827	8.272	EPSD	COSMIC;CCLE	9.540	Loss
Atypical_PIKK_ATM_ATM_ST	Q7Z6Z7	HUWE1	Q13315	ATM	S3248	E3249K	3249	Missense	proximal	1	no	13.231	12.280	EPSD	COSMIC	9.540	Down-regulation
Atypical_PIKK_ATM_ATM_ST	Q7Z6Z7	HUWE1	Q13315	ATM	S3248	S3255L	3255	Missense	distal	7	no	13.231	13.250	EPSD	COSMIC	9.540	Up-regulation
Atypical_PIKK_ATM_ATM_ST	Q7Z6Z7	HUWE1	Q13315	ATM	S3248	K3254N	3254	Missense	distal	6	no	13.231	13.242	EPSD	COSMIC	9.540	Up-regulation
Atypical_PIKK_ATM_ATM_ST	Q7Z6Z7	HUWE1	Q13315	ATM	S3248	E3249D	3249	Missense	proximal	1	no	13.231	13.097	EPSD	COSMIC	9.540	Down-regulation
Atypical_PIKK_ATM_ATM_ST	Q7Z6Z7	HUWE1	Q13315	ATM	S3263	H3264Y	3264	Missense	proximal	1	no	0.485	9.678	EPSD	COSMIC	9.540	Gain
Atypical_PIKK_ATM_ATM_ST	Q7Z6Z7	HUWE1	Q13315	ATM	S3373	G3368C	3368	Missense	distal	-5	no	10.639	10.677	EPSD	COSMIC	9.540	Up-regulation
Atypical_PIKK_ATM_ATM_ST	Q7Z6Z7	HUWE1	Q13315	ATM	S3422	A3415T	3415	Missense	distal	-7	no	10.803	10.818	EPSD	COSMIC	9.540	Up-regulation
Atypical_PIKK_ATM_ATM_ST	Q7Z6Z7	HUWE1	Q13315	ATM	S3422	L3426P	3426	Missense	distal	4	no	10.803	10.584	EPSD	COSMIC	9.540	Down-regulation
Atypical_PIKK_ATM_ATM_ST	Q7Z6Z7	HUWE1	Q13315	ATM	S3422	Y3424C	3424	Missense	proximal	2	no	10.803	10.410	EPSD	COSMIC	9.540	Down-regulation
Atypical_PIKK_ATM_ATM_ST	Q7Z6Z7	HUWE1	Q13315	ATM	S3662	E3659K	3659	Missense	distal	-3	no	9.935	10.002	EPSD	COSMIC	9.540	Up-regulation
Atypical_PIKK_ATM_ATM_ST	Q7Z6Z7	HUWE1	Q13315	ATM	S3662	E3659G	3659	Missense	distal	-3	no	9.935	10.373	EPSD	COSMIC	9.540	Up-regulation
Atypical_PIKK_ATM_ATM_ST	Q7Z6Z7	HUWE1	Q13315	ATM	S3695	V3691A	3691	Missense	distal	-4	no	13.868	14.348	EPSD;PhosphoSitePlus	COSMIC	9.540	Up-regulation
Atypical_PIKK_ATM_ATM_ST	Q7Z6Z7	HUWE1	Q13315	ATM	S3797	A3792V	3792	Missense	distal	-5	no	14.874	14.995	PhosphoSitePlus;EPSD	COSMIC	9.540	Up-regulation
Atypical_PIKK_ATM_ATM_ST	Q7Z6Z7	HUWE1	Q13315	ATM	S3797	E3795K	3795	Missense	proximal	-2	no	14.874	14.298	PhosphoSitePlus;EPSD	COSMIC	9.540	Down-regulation
Atypical_PIKK_ATM_ATM_ST	Q7Z6Z7	HUWE1	Q13315	ATM	S3797	R3804W	3804	Missense	distal	7	no	14.874	14.900	PhosphoSitePlus;EPSD	COSMIC	9.540	Up-regulation
Atypical_PIKK_ATM_ATM_ST	Q7Z6Z7	HUWE1	Q13315	ATM	S3799	A3792V	3792	Missense	distal	-7	no	10.218	9.834	EPSD	COSMIC	9.540	Down-regulation
Atypical_PIKK_ATM_ATM_ST	Q7Z6Z7	HUWE1	Q13315	ATM	S3799	E3806K	3806	Missense	distal	7	no	10.218	10.245	EPSD	COSMIC	9.540	Up-regulation
Atypical_PIKK_ATM_ATM_ST	Q7Z6Z7	HUWE1	Q13315	ATM	S3799	E3795K	3795	Missense	distal	-4	no	10.218	9.246	EPSD	COSMIC	9.540	Loss
Atypical_PIKK_ATM_ATM_ST	Q7Z6Z7	HUWE1	Q13315	ATM	S3799	R3804W	3804	Missense	distal	5	no	10.218	10.242	EPSD	COSMIC	9.540	Up-regulation
Atypical_PIKK_ATM_ATM_ST	Q7Z6Z7	HUWE1	Q13315	ATM	S3808	E3806K	3806	Missense	proximal	-2	no	11.029	10.453	EPSD	COSMIC	9.540	Down-regulation
Atypical_PIKK_ATM_ATM_ST	Q7Z6Z7	HUWE1	Q13315	ATM	S3808	R3804W	3804	Missense	distal	-4	no	11.029	10.553	EPSD	COSMIC	9.540	Down-regulation
Atypical_PIKK_ATM_ATM_ST	Q7Z6Z7	HUWE1	Q13315	ATM	T3822	Q3823H	3823	Missense	proximal	1	no	14.516	-0.393	EPSD	COSMIC	9.540	Loss
Atypical_PIKK_ATM_ATM_ST	Q7Z6Z7	HUWE1	Q13315	ATM	S3906	E3905K	3905	Missense	proximal	-1	no	14.815	14.412	EPSD	COSMIC	9.540	Down-regulation
Atypical_PIKK_ATM_ATM_ST	Q7Z6Z7	HUWE1	Q13315	ATM	S3906	V3900A	3900	Missense	distal	-6	no	14.815	15.051	EPSD	COSMIC	9.540	Up-regulation
Atypical_PIKK_ATM_ATM_ST	Q7Z6Z7	HUWE1	Q13315	ATM	S3906	K3912R	3912	Missense	distal	6	no	14.815	14.819	EPSD	COSMIC	9.540	Up-regulation
Atypical_PIKK_ATM_ATM_ST	Q7Z6Z7	HUWE1	Q13315	ATM	S3919	K3912R	3912	Missense	distal	-7	no	9.662	9.576	EPSD	COSMIC	9.540	Down-regulation
Atypical_PIKK_ATM_ATM_ST	Q7Z6Z7	HUWE1	Q13315	ATM	S3947	P3949L	3949	Missense	proximal	2	no	10.646	9.857	EPSD	COSMIC	9.540	Down-regulation
Atypical_PIKK_ATM_ATM_ST	Q7Z6Z7	HUWE1	Q13315	ATM	S4070	R4063W	4063	Missense	distal	-7	no	10.787	10.598	EPSD	COSMIC	9.540	Down-regulation
Atypical_PIKK_ATM_ATM_ST	Q7Z6Z7	HUWE1	Q13315	ATM	S4070	E4072D	4072	Missense	proximal	2	no	10.787	10.656	EPSD	COSMIC	9.540	Down-regulation
Atypical_PIKK_ATM_ATM_ST	Q7Z6Z7	HUWE1	Q13315	ATM	S4070	R4063Q	4063	Missense	distal	-7	no	10.787	10.987	EPSD	COSMIC	9.540	Up-regulation
Atypical_PIKK_ATM_ATM_ST	Q15648	MED1	Q13315	ATM	S434	G436V	436	Missense	proximal	2	no	11.174	11.140	EPSD	COSMIC	9.540	Down-regulation
Atypical_PIKK_ATM_ATM_ST	Q15648	MED1	Q13315	ATM	S621	T623P	623	Missense	proximal	2	no	11.383	11.190	EPSD	COSMIC	9.540	Down-regulation
Atypical_PIKK_ATM_ATM_ST	Q15648	MED1	Q13315	ATM	S621	G614E	614	Missense	distal	-7	no	11.383	12.251	EPSD	COSMIC	9.540	Up-regulation
Atypical_PIKK_ATM_ATM_ST	Q15648	MED1	Q13315	ATM	S719	P722T	722	Missense	distal	3	no	14.366	14.295	EPSD	COSMIC	9.540	Down-regulation
Atypical_PIKK_ATM_ATM_ST	Q15648	MED1	Q13315	ATM	S743	H737Y	737	Missense	distal	-6	no	13.731	13.661	EPSD	COSMIC	9.540	Down-regulation
Atypical_PIKK_ATM_ATM_ST	Q15648	MED1	Q13315	ATM	S791	K792Q	792	Missense	proximal	1	no	5.052	11.900	EPSD	COSMIC	9.540	Gain
Atypical_PIKK_ATM_ATM_ST	Q15648	MED1	Q13315	ATM	S816	S810C	810	Missense	distal	-6	no	14.078	13.698	EPSD;PhosphoSitePlus	COSMIC	9.540	Down-regulation
Atypical_PIKK_ATM_ATM_ST	Q15648	MED1	Q13315	ATM	S816	H815R	815	Missense	proximal	-1	no	14.078	13.907	EPSD;PhosphoSitePlus	COSMIC	9.540	Down-regulation
Atypical_PIKK_ATM_ATM_ST	Q15648	MED1	Q13315	ATM	S848	L841V	841	Missense	distal	-7	no	11.270	11.377	EPSD	COSMIC	9.540	Up-regulation
Atypical_PIKK_ATM_ATM_ST	Q15648	MED1	Q13315	ATM	S848	L841F	841	Missense	distal	-7	no	11.270	11.028	EPSD	COSMIC;GDSC;CCLE	9.540	Down-regulation
Atypical_PIKK_ATM_ATM_ST	Q15648	MED1	Q13315	ATM	S872	P867L	867	Missense	distal	-5	no	15.569	15.589	PhosphoSitePlus;EPSD	COSMIC	9.540	Up-regulation
Atypical_PIKK_ATM_ATM_ST	Q15648	MED1	Q13315	ATM	S874	P867L	867	Missense	distal	-7	no	15.554	15.202	EPSD;PhosphoSitePlus	COSMIC	9.540	Down-regulation
Atypical_PIKK_ATM_ATM_ST	Q15648	MED1	Q13315	ATM	S900	L906F	906	Missense	distal	6	no	12.661	12.641	EPSD	COSMIC	9.540	Down-regulation
Atypical_PIKK_ATM_ATM_ST	Q15648	MED1	Q13315	ATM	S953	G955S	955	Missense	proximal	2	no	13.399	14.257	EPSD;PhosphoSitePlus	COSMIC	9.540	Up-regulation
Atypical_PIKK_ATM_ATM_ST	Q15648	MED1	Q13315	ATM	S953	H950Y	950	Missense	distal	-3	no	13.399	13.437	EPSD;PhosphoSitePlus	COSMIC	9.540	Up-regulation
Atypical_PIKK_ATM_ATM_ST	Q15648	MED1	Q13315	ATM	S1021	P1022Q	1022	Missense	proximal	1	no	8.044	12.846	EPSD	COSMIC	9.540	Gain
Atypical_PIKK_ATM_ATM_ST	Q15648	MED1	Q13315	ATM	S1049	G1044C	1044	Missense	distal	-5	no	15.150	15.188	EPSD	COSMIC	9.540	Up-regulation
Atypical_PIKK_ATM_ATM_ST	Q15648	MED1	Q13315	ATM	S1049	P1052F	1052	Missense	distal	3	no	15.150	15.580	EPSD	COSMIC	9.540	Up-regulation
Atypical_PIKK_ATM_ATM_ST	Q15648	MED1	Q13315	ATM	S1049	P1052S	1052	Missense	distal	3	no	15.150	14.998	EPSD	COSMIC	9.540	Down-regulation
Atypical_PIKK_ATM_ATM_ST	Q15648	MED1	Q13315	ATM	S1049	S1042L	1042	Missense	distal	-7	no	15.150	14.562	EPSD	COSMIC	9.540	Down-regulation
Atypical_PIKK_ATM_ATM_ST	Q15648	MED1	Q13315	ATM	T1051	G1044C	1044	Missense	distal	-7	no	9.640	9.479	EPSD	COSMIC	9.540	Loss
Atypical_PIKK_ATM_ATM_ST	Q15648	MED1	Q13315	ATM	T1051	P1052F	1052	Missense	proximal	1	no	9.640	4.205	EPSD	COSMIC	9.540	Loss
Atypical_PIKK_ATM_ATM_ST	Q15648	MED1	Q13315	ATM	T1051	P1052S	1052	Missense	proximal	1	no	9.640	2.665	EPSD	COSMIC	9.540	Loss
Atypical_PIKK_ATM_ATM_ST	Q15648	MED1	Q13315	ATM	S1092	K1095E	1095	Missense	distal	3	no	10.245	9.956	EPSD	COSMIC;GDSC;CCLE	9.540	Down-regulation
Atypical_PIKK_ATM_ATM_ST	Q15648	MED1	Q13315	ATM	S1094	K1095E	1095	Missense	proximal	1	no	8.913	9.864	EPSD	COSMIC;GDSC;CCLE	9.540	Gain
Atypical_PIKK_ATM_ATM_ST	Q15648	MED1	Q13315	ATM	S1134	S1137F	1137	Missense	distal	3	no	14.814	15.396	EPSD;PhosphoSitePlus	COSMIC	9.540	Up-regulation
Atypical_PIKK_ATM_ATM_ST	Q15648	MED1	Q13315	ATM	S1141	S1137F	1137	Missense	distal	-4	no	16.267	14.868	EPSD;PhosphoSitePlus	COSMIC	9.540	Down-regulation
Atypical_PIKK_ATM_ATM_ST	Q15648	MED1	Q13315	ATM	S1156	P1157A	1157	Missense	proximal	1	no	10.439	8.368	EPSD	COSMIC	9.540	Loss
Atypical_PIKK_ATM_ATM_ST	Q15648	MED1	Q13315	ATM	S1223	P1217L	1217	Missense	distal	-6	no	9.627	9.398	EPSD	COSMIC	9.540	Loss
Atypical_PIKK_ATM_ATM_ST	Q15648	MED1	Q13315	ATM	S1223	G1228D	1228	Missense	distal	5	no	9.627	9.536	EPSD	COSMIC	9.540	Loss
Atypical_PIKK_ATM_ATM_ST	Q15648	MED1	Q13315	ATM	S1256	P1260S	1260	Missense	distal	4	no	13.636	13.514	EPSD	COSMIC	9.540	Down-regulation
Atypical_PIKK_ATM_ATM_ST	Q15648	MED1	Q13315	ATM	S1276	S1283F	1283	Missense	distal	7	no	10.082	10.142	EPSD	COSMIC	9.540	Up-regulation
Atypical_PIKK_ATM_ATM_ST	Q15648	MED1	Q13315	ATM	S1276	S1272F	1272	Missense	distal	-4	no	10.082	8.683	EPSD	COSMIC	9.540	Loss
Atypical_PIKK_ATM_ATM_ST	Q15648	MED1	Q13315	ATM	S1276	S1278A	1278	Missense	proximal	2	no	10.082	9.499	EPSD	COSMIC	9.540	Loss
Atypical_PIKK_ATM_ATM_ST	Q15648	MED1	Q13315	ATM	S1283	S1283F	1283	Missense	central	0	yes	13.483	0.000	EPSD	COSMIC	9.540	Loss
Atypical_PIKK_ATM_ATM_ST	Q15648	MED1	Q13315	ATM	S1283	S1290Y	1290	Missense	distal	7	no	13.483	13.517	EPSD	COSMIC	9.540	Up-regulation
Atypical_PIKK_ATM_ATM_ST	Q15648	MED1	Q13315	ATM	S1283	S1278A	1278	Missense	distal	-5	no	13.483	13.475	EPSD	COSMIC	9.540	Down-regulation
Atypical_PIKK_ATM_ATM_ST	Q15648	MED1	Q13315	ATM	S1465	S1467L	1467	Missense	proximal	2	no	11.512	10.268	EPSD	COSMIC	9.540	Down-regulation
Atypical_PIKK_ATM_ATM_ST	Q15648	MED1	Q13315	ATM	S1465	P1458S	1458	Missense	distal	-7	no	11.512	11.748	EPSD	COSMIC	9.540	Up-regulation
Atypical_PIKK_ATM_ATM_ST	Q15648	MED1	Q13315	ATM	S1467	E1473D	1473	Missense	distal	6	no	9.794	9.748	EPSD	COSMIC	9.540	Down-regulation
Atypical_PIKK_ATM_ATM_ST	Q15648	MED1	Q13315	ATM	S1467	S1467L	1467	Missense	central	0	yes	9.794	0.000	EPSD	COSMIC	9.540	Loss
Atypical_PIKK_ATM_ATM_ST	Q15648	MED1	Q13315	ATM	S1479	E1473D	1473	Missense	distal	-6	no	9.676	9.461	EPSD	COSMIC	9.540	Loss
Atypical_PIKK_ATM_ATM_ST	Q15648	MED1	Q13315	ATM	S1479	S1479N	1479	Missense	central	0	yes	9.676	0.000	EPSD	COSMIC	9.540	Loss
Atypical_PIKK_ATM_ATM_ST	Q15648	MED1	Q13315	ATM	S1525	H1526Y	1526	Missense	proximal	1	no	0.488	9.681	EPSD	COSMIC	9.540	Gain
Atypical_PIKK_ATM_ATM_ST	Q15648	MED1	Q13315	ATM	S1561	P1562S	1562	Missense	proximal	1	no	11.373	4.398	EPSD	COSMIC	9.540	Loss
Atypical_PIKK_ATM_ATM_ST	P07900	HSP90AA1	Q13315	ATM	T5	E4G	4	Missense	proximal	-1	no	12.174	11.772	EPSD;PhosphoSitePlus	COSMIC	9.540	Down-regulation
Atypical_PIKK_ATM_ATM_ST	P07900	HSP90AA1	Q13315	ATM	T7	E4G	4	Missense	distal	-3	no	12.073	12.511	PhosphoSitePlus;EPSD	COSMIC	9.540	Up-regulation
Atypical_PIKK_ATM_ATM_ST	P07900	HSP90AA1	Q13315	ATM	S53	K58T	58	Missense	distal	5	no	9.606	9.585	EPSD	COSMIC	9.540	Down-regulation
Atypical_PIKK_ATM_ATM_ST	P07900	HSP90AA1	Q13315	ATM	S63	K58T	58	Missense	distal	-5	no	10.340	10.335	EPSD	COSMIC	9.540	Down-regulation
Atypical_PIKK_ATM_ATM_ST	P07900	HSP90AA1	Q13315	ATM	S165	Y160C	160	Missense	distal	-5	no	9.812	9.881	EPSD	COSMIC	9.540	Up-regulation
Atypical_PIKK_ATM_ATM_ST	P07900	HSP90AA1	Q13315	ATM	S252	E248Q	248	Missense	distal	-4	no	9.817	9.094	EPSD	COSMIC;CCLE	9.540	Loss
Atypical_PIKK_ATM_ATM_ST	P07900	HSP90AA1	Q13315	ATM	S252	P256R	256	Missense	distal	4	no	9.817	9.877	EPSD	COSMIC	9.540	Up-regulation
Atypical_PIKK_ATM_ATM_ST	P07900	HSP90AA1	Q13315	ATM	S315	D319G	319	Missense	distal	4	no	11.255	11.176	EPSD	COSMIC	9.540	Down-regulation
Atypical_PIKK_ATM_ATM_ST	P07900	HSP90AA1	Q13315	ATM	S315	E321D	321	Missense	distal	6	no	11.255	11.208	EPSD	COSMIC	9.540	Down-regulation
Atypical_PIKK_ATM_ATM_ST	P07900	HSP90AA1	Q13315	ATM	S453	H450L	450	Missense	distal	-3	no	13.946	14.061	EPSD	COSMIC	9.540	Up-regulation
Atypical_PIKK_ATM_ATM_ST	P07900	HSP90AA1	Q13315	ATM	S453	D452V	452	Missense	proximal	-1	no	13.946	13.577	EPSD	COSMIC	9.540	Down-regulation
Atypical_PIKK_ATM_ATM_ST	P07900	HSP90AA1	Q13315	ATM	S453	S453C	453	Missense	central	0	yes	13.946	0.000	EPSD	COSMIC	9.540	Loss
Atypical_PIKK_ATM_ATM_ST	P07900	HSP90AA1	Q13315	ATM	S595	P596S	596	Missense	proximal	1	no	11.393	4.418	EPSD	COSMIC;CCLE	9.540	Loss
Atypical_PIKK_ATM_ATM_ST	P07900	HSP90AA1	Q13315	ATM	S726	E729K	729	Missense	distal	3	no	9.405	9.693	EPSD	COSMIC	9.540	Gain
Atypical_PIKK_ATM_ATM_ST	Q9BQ15	NABP2	Q13315	ATM	T117	P113S	113	Missense	distal	-4	no	12.515	13.184	PhosphoSitePlus	COSMIC	9.540	Up-regulation
Atypical_PIKK_ATM_ATM_ST	Q9BQ15	NABP2	Q13315	ATM	T117	A120T	120	Missense	distal	3	no	12.515	12.540	PhosphoSitePlus	COSMIC	9.540	Up-regulation
Atypical_PIKK_ATM_ATM_ST	Q9BQ15	NABP2	Q13315	ATM	S134	P131S	131	Missense	distal	-3	no	14.314	14.117	EPSD	COSMIC	9.540	Down-regulation
Atypical_PIKK_ATM_ATM_ST	Q9BQ15	NABP2	Q13315	ATM	S134	D128E	128	Missense	distal	-6	no	14.314	14.528	EPSD	COSMIC	9.540	Up-regulation
Atypical_PIKK_ATM_ATM_ST	Q9BQ15	NABP2	Q13315	ATM	S182	P175H	175	Missense	distal	-7	no	12.866	12.789	EPSD	COSMIC	9.540	Down-regulation
Atypical_PIKK_ATM_ATM_ST	P46527	CDKN1B	Q13315	ATM	S106	Q107R	107	Missense	proximal	1	no	13.844	7.193	EPSD	COSMIC	9.540	Loss
Atypical_PIKK_ATM_ATM_ST	P46527	CDKN1B	Q13315	ATM	S106	D108N	108	Missense	proximal	2	no	13.844	12.823	EPSD	COSMIC	9.540	Down-regulation
Atypical_PIKK_ATM_ATM_ST	P46527	CDKN1B	Q13315	ATM	S140	P133T	133	Missense	distal	-7	no	16.385	16.540	PhosphoSitePlus	COSMIC	9.540	Up-regulation
Atypical_PIKK_ATM_ATM_ST	P46527	CDKN1B	Q13315	ATM	S140	P137S	137	Missense	distal	-3	no	16.385	16.188	PhosphoSitePlus	COSMIC	9.540	Down-regulation
Atypical_PIKK_ATM_ATM_ST	P46527	CDKN1B	Q13315	ATM	S140	S140R	140	Missense	central	0	yes	16.385	0.000	PhosphoSitePlus	COSMIC	9.540	Loss
Atypical_PIKK_ATM_ATM_ST	P46527	CDKN1B	Q13315	ATM	S140	D136G	136	Missense	distal	-4	no	16.385	15.601	PhosphoSitePlus	COSMIC;GDSC	9.540	Down-regulation
Atypical_PIKK_ATM_ATM_ST	P46527	CDKN1B	Q13315	ATM	S140	E146V	146	Missense	distal	6	no	16.385	16.336	PhosphoSitePlus	COSMIC	9.540	Down-regulation
Atypical_PIKK_ATM_ATM_ST	P46527	CDKN1B	Q13315	ATM	S183	V184L	184	Missense	proximal	1	no	2.945	9.583	EPSD	COSMIC	9.540	Gain
Atypical_PIKK_ATM_ATM_ST	P38398	BRCA1	Q13315	ATM	S114	D120A	120	Missense	distal	6	no	11.197	11.225	EPSD	COSMIC	9.540	Up-regulation
Atypical_PIKK_ATM_ATM_ST	P38398	BRCA1	Q13315	ATM	S114	P115L	115	Missense	proximal	1	no	11.197	9.642	EPSD	COSMIC	9.540	Down-regulation
Atypical_PIKK_ATM_ATM_ST	P38398	BRCA1	Q13315	ATM	S114	F107Y	107	Missense	distal	-7	no	11.197	11.731	EPSD	COSMIC	9.540	Up-regulation
Atypical_PIKK_ATM_ATM_ST	P38398	BRCA1	Q13315	ATM	S114	N113S	113	Missense	proximal	-1	no	11.197	11.252	EPSD	COSMIC	9.540	Up-regulation
Atypical_PIKK_ATM_ATM_ST	P38398	BRCA1	Q13315	ATM	S114	E111K	111	Missense	distal	-3	no	11.197	11.264	EPSD	COSMIC	9.540	Up-regulation
Atypical_PIKK_ATM_ATM_ST	P38398	BRCA1	Q13315	ATM	S114	A108V	108	Missense	distal	-6	no	11.197	10.960	EPSD	COSMIC	9.540	Down-regulation
Atypical_PIKK_ATM_ATM_ST	P38398	BRCA1	Q13315	ATM	S114	E116K	116	Missense	proximal	2	no	11.197	9.866	EPSD	COSMIC	9.540	Down-regulation
Atypical_PIKK_ATM_ATM_ST	P38398	BRCA1	Q13315	ATM	S114	P115R	115	Missense	proximal	1	no	11.197	9.347	EPSD	COSMIC	9.540	Loss
Atypical_PIKK_ATM_ATM_ST	P38398	BRCA1	Q13315	ATM	S308	K309Q	309	Missense	proximal	1	no	6.987	13.835	EPSD	COSMIC	9.540	Gain
Atypical_PIKK_ATM_ATM_ST	P38398	BRCA1	Q13315	ATM	S316	W321L	321	Missense	distal	5	no	14.757	14.732	EPSD	COSMIC	9.540	Down-regulation
Atypical_PIKK_ATM_ATM_ST	P38398	BRCA1	Q13315	ATM	S316	P311A	311	Missense	distal	-5	no	14.757	14.746	EPSD	COSMIC	9.540	Down-regulation
Atypical_PIKK_ATM_ATM_ST	P38398	BRCA1	Q13315	ATM	S316	K309Q	309	Missense	distal	-7	no	14.757	14.871	EPSD	COSMIC	9.540	Up-regulation
Atypical_PIKK_ATM_ATM_ST	P38398	BRCA1	Q13315	ATM	S316	Q310H	310	Missense	distal	-6	no	14.757	14.615	EPSD	COSMIC	9.540	Down-regulation
Atypical_PIKK_ATM_ATM_ST	P38398	BRCA1	Q13315	ATM	S316	S316G	316	Missense	central	0	yes	14.757	0.000	EPSD	COSMIC	9.540	Loss
Atypical_PIKK_ATM_ATM_ST	P38398	BRCA1	Q13315	ATM	S316	A314S	314	Missense	proximal	-2	no	14.757	14.945	EPSD	COSMIC	9.540	Up-regulation
Atypical_PIKK_ATM_ATM_ST	P38398	BRCA1	Q13315	ATM	S324	W321L	321	Missense	distal	-3	no	10.337	10.236	EPSD	COSMIC	9.540	Down-regulation
Atypical_PIKK_ATM_ATM_ST	P38398	BRCA1	Q13315	ATM	S324	C328Y	328	Missense	distal	4	no	10.337	10.131	EPSD	COSMIC;GDSC;CCLE	9.540	Down-regulation
Atypical_PIKK_ATM_ATM_ST	P38398	BRCA1	Q13315	ATM	S324	D330N	330	Missense	distal	6	no	10.337	10.349	EPSD	COSMIC	9.540	Up-regulation
Atypical_PIKK_ATM_ATM_ST	P38398	BRCA1	Q13315	ATM	S324	R331G	331	Missense	distal	7	no	10.337	10.344	EPSD	COSMIC	9.540	Up-regulation
Atypical_PIKK_ATM_ATM_ST	P38398	BRCA1	Q13315	ATM	S324	S324I	324	Missense	central	0	yes	10.337	0.000	EPSD	COSMIC	9.540	Loss
Atypical_PIKK_ATM_ATM_ST	P38398	BRCA1	Q13315	ATM	S324	T327A	327	Missense	distal	3	no	10.337	10.313	EPSD	COSMIC	9.540	Down-regulation
Atypical_PIKK_ATM_ATM_ST	P38398	BRCA1	Q13315	ATM	S395	G401E	401	Missense	distal	6	no	11.215	11.258	EPSD	COSMIC;GDSC;CCLE	9.540	Up-regulation
Atypical_PIKK_ATM_ATM_ST	P38398	BRCA1	Q13315	ATM	S395	H399R	399	Missense	distal	4	no	11.215	11.279	EPSD	COSMIC	9.540	Up-regulation
Atypical_PIKK_ATM_ATM_ST	P38398	BRCA1	Q13315	ATM	S395	S395F	395	Missense	central	0	yes	11.215	0.000	EPSD	COSMIC	9.540	Loss
Atypical_PIKK_ATM_ATM_ST	P38398	BRCA1	Q13315	ATM	S395	G401V	401	Missense	distal	6	no	11.215	11.210	EPSD	COSMIC	9.540	Down-regulation
Atypical_PIKK_ATM_ATM_ST	P38398	BRCA1	Q13315	ATM	S425	S426L	426	Missense	proximal	1	no	4.558	9.979	EPSD	COSMIC	9.540	Gain
Atypical_PIKK_ATM_ATM_ST	P38398	BRCA1	Q13315	ATM	S426	V419E	419	Missense	distal	-7	no	8.712	9.548	EPSD	COSMIC	9.540	Gain
Atypical_PIKK_ATM_ATM_ST	P38398	BRCA1	Q13315	ATM	S434	D430N	430	Missense	distal	-4	no	9.615	8.691	EPSD	COSMIC	9.540	Loss
Atypical_PIKK_ATM_ATM_ST	P38398	BRCA1	Q13315	ATM	S434	H437D	437	Missense	distal	3	no	9.615	9.575	EPSD	COSMIC	9.540	Down-regulation
Atypical_PIKK_ATM_ATM_ST	P38398	BRCA1	Q13315	ATM	S434	S434N	434	Missense	central	0	yes	9.615	0.000	EPSD	COSMIC	9.540	Loss
Atypical_PIKK_ATM_ATM_ST	P38398	BRCA1	Q13315	ATM	S434	L432V	432	Missense	proximal	-2	no	9.615	9.340	EPSD	COSMIC	9.540	Loss
Atypical_PIKK_ATM_ATM_ST	P38398	BRCA1	Q13315	ATM	S434	D435Y	435	Missense	proximal	1	no	9.615	9.931	EPSD	COSMIC;GDSC;CCLE	9.540	Up-regulation
Atypical_PIKK_ATM_ATM_ST	P38398	BRCA1	Q13315	ATM	S449	H448R	448	Missense	proximal	-1	no	10.561	10.391	EPSD	COSMIC	9.540	Down-regulation
Atypical_PIKK_ATM_ATM_ST	P38398	BRCA1	Q13315	ATM	S449	K443E	443	Missense	distal	-6	no	10.561	10.862	EPSD	COSMIC	9.540	Up-regulation
Atypical_PIKK_ATM_ATM_ST	P38398	BRCA1	Q13315	ATM	S449	N455T	455	Missense	distal	6	no	10.561	10.562	EPSD	COSMIC	9.540	Up-regulation
Atypical_PIKK_ATM_ATM_ST	P38398	BRCA1	Q13315	ATM	S449	I456T	456	Missense	distal	7	no	10.561	10.546	EPSD	COSMIC;GDSC;CCLE	9.540	Down-regulation
Atypical_PIKK_ATM_ATM_ST	P38398	BRCA1	Q13315	ATM	T528	G535R	535	Missense	distal	7	no	10.192	10.186	EPSD	COSMIC	9.540	Down-regulation
Atypical_PIKK_ATM_ATM_ST	P38398	BRCA1	Q13315	ATM	T528	I532F	532	Missense	distal	4	no	10.192	10.357	EPSD	COSMIC	9.540	Up-regulation
Atypical_PIKK_ATM_ATM_ST	P38398	BRCA1	Q13315	ATM	S603	K604E	604	Missense	proximal	1	no	8.678	9.630	EPSD	COSMIC;GDSC;CCLE	9.540	Gain
Atypical_PIKK_ATM_ATM_ST	P38398	BRCA1	Q13315	ATM	S632	N630H	630	Missense	proximal	-2	no	11.021	10.773	EPSD	COSMIC	9.540	Down-regulation
Atypical_PIKK_ATM_ATM_ST	P38398	BRCA1	Q13315	ATM	S632	P633S	633	Missense	proximal	1	no	11.021	4.046	EPSD	COSMIC	9.540	Loss
Atypical_PIKK_ATM_ATM_ST	P38398	BRCA1	Q13315	ATM	S632	P634S	634	Missense	proximal	2	no	11.021	11.476	EPSD	COSMIC	9.540	Up-regulation
Atypical_PIKK_ATM_ATM_ST	P38398	BRCA1	Q13315	ATM	S632	S628N	628	Missense	distal	-4	no	11.021	10.093	EPSD	COSMIC	9.540	Down-regulation
Atypical_PIKK_ATM_ATM_ST	P38398	BRCA1	Q13315	ATM	S632	T637N	637	Missense	distal	5	no	11.021	11.012	EPSD	COSMIC	9.540	Down-regulation
Atypical_PIKK_ATM_ATM_ST	P38398	BRCA1	Q13315	ATM	S632	E638D	638	Missense	distal	6	no	11.021	10.974	EPSD	COSMIC	9.540	Down-regulation
Atypical_PIKK_ATM_ATM_ST	P38398	BRCA1	Q13315	ATM	S632	C636F	636	Missense	distal	4	no	11.021	11.339	EPSD	COSMIC	9.540	Up-regulation
Atypical_PIKK_ATM_ATM_ST	P38398	BRCA1	Q13315	ATM	S632	P634R	634	Missense	proximal	2	no	11.021	10.478	EPSD	COSMIC	9.540	Down-regulation
Atypical_PIKK_ATM_ATM_ST	P38398	BRCA1	Q13315	ATM	S647	E648Q	648	Missense	proximal	1	no	8.818	14.715	EPSD	COSMIC	9.540	Gain
Atypical_PIKK_ATM_ATM_ST	P38398	BRCA1	Q13315	ATM	S694	Q687P	687	Missense	distal	-7	no	10.201	10.164	EPSD	COSMIC;GDSC;CCLE	9.540	Down-regulation
Atypical_PIKK_ATM_ATM_ST	P38398	BRCA1	Q13315	ATM	S694	D693N	693	Missense	proximal	-1	no	10.201	10.200	EPSD	COSMIC	9.540	Down-regulation
Atypical_PIKK_ATM_ATM_ST	P38398	BRCA1	Q13315	ATM	S694	S694N	694	Missense	central	0	yes	10.201	0.000	EPSD	COSMIC	9.540	Loss
Atypical_PIKK_ATM_ATM_ST	P38398	BRCA1	Q13315	ATM	S694	R691I	691	Missense	distal	-3	no	10.201	10.130	EPSD	COSMIC	9.540	Down-regulation
Atypical_PIKK_ATM_ATM_ST	P38398	BRCA1	Q13315	ATM	S694	D695N	695	Missense	proximal	1	no	10.201	6.370	EPSD	COSMIC	9.540	Loss
Atypical_PIKK_ATM_ATM_ST	P38398	BRCA1	Q13315	ATM	S694	S694F	694	Missense	central	0	yes	10.201	0.000	EPSD	COSMIC	9.540	Loss
Atypical_PIKK_ATM_ATM_ST	P38398	BRCA1	Q13315	ATM	S694	S694Y	694	Missense	central	0	yes	10.201	0.000	EPSD	COSMIC	9.540	Loss
Atypical_PIKK_ATM_ATM_ST	P38398	BRCA1	Q13315	ATM	S753	L750I	750	Missense	distal	-3	no	10.758	11.218	EPSD	COSMIC	9.540	Up-regulation
Atypical_PIKK_ATM_ATM_ST	P38398	BRCA1	Q13315	ATM	S753	V757A	757	Missense	distal	4	no	10.758	10.105	EPSD	COSMIC	9.540	Down-regulation
Atypical_PIKK_ATM_ATM_ST	P38398	BRCA1	Q13315	ATM	S753	L758F	758	Missense	distal	5	no	10.758	10.899	EPSD	COSMIC	9.540	Up-regulation
Atypical_PIKK_ATM_ATM_ST	P38398	BRCA1	Q13315	ATM	S753	G754E	754	Missense	proximal	1	no	10.758	11.335	EPSD	COSMIC	9.540	Up-regulation
Atypical_PIKK_ATM_ATM_ST	P38398	BRCA1	Q13315	ATM	S753	M751I	751	Missense	proximal	-2	no	10.758	10.506	EPSD	COSMIC	9.540	Down-regulation
Atypical_PIKK_ATM_ATM_ST	P38398	BRCA1	Q13315	ATM	S803	N810T	810	Missense	distal	7	no	14.713	14.714	EPSD	COSMIC;GDSC;CCLE	9.540	Up-regulation
Atypical_PIKK_ATM_ATM_ST	P38398	BRCA1	Q13315	ATM	S803	N810Y	810	Missense	distal	7	no	14.713	14.732	EPSD	COSMIC	9.540	Up-regulation
Atypical_PIKK_ATM_ATM_ST	P38398	BRCA1	Q13315	ATM	S803	E809G	809	Missense	distal	6	no	14.713	14.670	EPSD	COSMIC	9.540	Down-regulation
Atypical_PIKK_ATM_ATM_ST	P38398	BRCA1	Q13315	ATM	S803	P798S	798	Missense	distal	-5	no	14.713	14.709	EPSD	COSMIC	9.540	Down-regulation
Atypical_PIKK_ATM_ATM_ST	P38398	BRCA1	Q13315	ATM	S803	A807T	807	Missense	distal	4	no	14.713	15.148	EPSD	COSMIC	9.540	Up-regulation
Atypical_PIKK_ATM_ATM_ST	P38398	BRCA1	Q13315	ATM	S803	T796A	796	Missense	distal	-7	no	14.713	14.697	EPSD	COSMIC	9.540	Down-regulation
Atypical_PIKK_ATM_ATM_ST	P38398	BRCA1	Q13315	ATM	S840	E842K	842	Missense	proximal	2	no	9.728	8.397	EPSD	COSMIC	9.540	Loss
Atypical_PIKK_ATM_ATM_ST	P38398	BRCA1	Q13315	ATM	S840	R841W	841	Missense	proximal	1	no	9.728	3.775	EPSD	COSMIC	9.540	Loss
Atypical_PIKK_ATM_ATM_ST	P38398	BRCA1	Q13315	ATM	S840	T843A	843	Missense	distal	3	no	9.728	9.704	EPSD	COSMIC;GDSC;CCLE	9.540	Down-regulation
Atypical_PIKK_ATM_ATM_ST	P38398	BRCA1	Q13315	ATM	S896	Q895R	895	Missense	proximal	-1	no	9.789	9.481	EPSD	COSMIC	9.540	Loss
Atypical_PIKK_ATM_ATM_ST	P38398	BRCA1	Q13315	ATM	S896	G890W	890	Missense	distal	-6	no	9.789	9.642	EPSD	COSMIC	9.540	Down-regulation
Atypical_PIKK_ATM_ATM_ST	P38398	BRCA1	Q13315	ATM	S896	G890V	890	Missense	distal	-6	no	9.789	9.734	EPSD	COSMIC;GDSC;CCLE	9.540	Down-regulation
Atypical_PIKK_ATM_ATM_ST	P38398	BRCA1	Q13315	ATM	S896	E902Q	902	Missense	distal	6	no	9.789	9.742	EPSD	COSMIC	9.540	Down-regulation
Atypical_PIKK_ATM_ATM_ST	P38398	BRCA1	Q13315	ATM	S896	G890R	890	Missense	distal	-6	no	9.789	9.810	EPSD	COSMIC	9.540	Up-regulation
Atypical_PIKK_ATM_ATM_ST	P38398	BRCA1	Q13315	ATM	S896	K898E	898	Missense	proximal	2	no	9.789	11.120	EPSD	COSMIC	9.540	Up-regulation
Atypical_PIKK_ATM_ATM_ST	P38398	BRCA1	Q13315	ATM	S956	R951M	951	Missense	distal	-5	no	13.238	13.247	EPSD	COSMIC	9.540	Up-regulation
Atypical_PIKK_ATM_ATM_ST	P38398	BRCA1	Q13315	ATM	S956	E962K	962	Missense	distal	6	no	13.238	13.193	EPSD	COSMIC;GDSC;CCLE	9.540	Down-regulation
Atypical_PIKK_ATM_ATM_ST	P38398	BRCA1	Q13315	ATM	S956	R951K	951	Missense	distal	-5	no	13.238	13.079	EPSD	COSMIC	9.540	Down-regulation
Atypical_PIKK_ATM_ATM_ST	P38398	BRCA1	Q13315	ATM	S956	C953Y	953	Missense	distal	-3	no	13.238	13.203	EPSD	COSMIC	9.540	Down-regulation
Atypical_PIKK_ATM_ATM_ST	P38398	BRCA1	Q13315	ATM	S1009	E1011K	1011	Missense	proximal	2	no	11.428	10.098	EPSD	COSMIC	9.540	Down-regulation
Atypical_PIKK_ATM_ATM_ST	P38398	BRCA1	Q13315	ATM	S1009	M1008I	1008	Missense	proximal	-1	no	11.428	11.499	EPSD	COSMIC;GDSC	9.540	Up-regulation
Atypical_PIKK_ATM_ATM_ST	P38398	BRCA1	Q13315	ATM	S1009	M1014I	1014	Missense	distal	5	no	11.428	11.453	EPSD	COSMIC;GDSC;CCLE	9.540	Up-regulation
Atypical_PIKK_ATM_ATM_ST	P38398	BRCA1	Q13315	ATM	S1009	M1014K	1014	Missense	distal	5	no	11.428	11.247	EPSD	COSMIC	9.540	Down-regulation
Atypical_PIKK_ATM_ATM_ST	P38398	BRCA1	Q13315	ATM	S1009	N1016I	1016	Missense	distal	7	no	11.428	11.445	EPSD	COSMIC	9.540	Up-regulation
Atypical_PIKK_ATM_ATM_ST	P38398	BRCA1	Q13315	ATM	S1009	S1009F	1009	Missense	central	0	yes	11.428	0.000	EPSD	COSMIC	9.540	Loss
Atypical_PIKK_ATM_ATM_ST	P38398	BRCA1	Q13315	ATM	S1009	E1013D	1013	Missense	distal	4	no	11.428	11.934	EPSD	COSMIC	9.540	Up-regulation
Atypical_PIKK_ATM_ATM_ST	P38398	BRCA1	Q13315	ATM	S1143	S1140G	1140	Missense	distal	-3	no	15.311	15.589	EPSD	COSMIC;GDSC	9.540	Up-regulation
Atypical_PIKK_ATM_ATM_ST	P38398	BRCA1	Q13315	ATM	S1143	G1138E	1138	Missense	distal	-5	no	15.311	15.091	EPSD	COSMIC	9.540	Down-regulation
Atypical_PIKK_ATM_ATM_ST	P38398	BRCA1	Q13315	ATM	S1143	P1150S	1150	Missense	distal	7	no	15.311	15.292	EPSD	COSMIC	9.540	Down-regulation
Atypical_PIKK_ATM_ATM_ST	P38398	BRCA1	Q13315	ATM	S1174	S1180I	1180	Missense	distal	6	no	9.587	9.547	EPSD	COSMIC	9.540	Down-regulation
Atypical_PIKK_ATM_ATM_ST	P38398	BRCA1	Q13315	ATM	S1174	E1167K	1167	Missense	distal	-7	no	9.587	8.919	EPSD	COSMIC	9.540	Loss
Atypical_PIKK_ATM_ATM_ST	P38398	BRCA1	Q13315	ATM	S1189	K1183R	1183	Missense	distal	-6	no	12.539	12.472	EPSD;PhosphoSitePlus	COSMIC	9.540	Down-regulation
Atypical_PIKK_ATM_ATM_ST	P38398	BRCA1	Q13315	ATM	S1189	E1185Q	1185	Missense	distal	-4	no	12.539	11.816	EPSD;PhosphoSitePlus	COSMIC	9.540	Down-regulation
Atypical_PIKK_ATM_ATM_ST	P38398	BRCA1	Q13315	ATM	S1189	P1190H	1190	Missense	proximal	1	no	12.539	2.432	EPSD;PhosphoSitePlus	COSMIC;GDSC;CCLE	9.540	Loss
Atypical_PIKK_ATM_ATM_ST	P38398	BRCA1	Q13315	ATM	S1189	P1190F	1190	Missense	proximal	1	no	12.539	7.104	EPSD;PhosphoSitePlus	COSMIC	9.540	Loss
Atypical_PIKK_ATM_ATM_ST	P38398	BRCA1	Q13315	ATM	S1189	Q1182H	1182	Missense	distal	-7	no	12.539	12.425	EPSD;PhosphoSitePlus	COSMIC	9.540	Down-regulation
Atypical_PIKK_ATM_ATM_ST	P38398	BRCA1	Q13315	ATM	S1189	P1192F	1192	Missense	distal	3	no	12.539	12.969	EPSD;PhosphoSitePlus	COSMIC	9.540	Up-regulation
Atypical_PIKK_ATM_ATM_ST	P38398	BRCA1	Q13315	ATM	S1189	P1190L	1190	Missense	proximal	1	no	12.539	10.984	EPSD;PhosphoSitePlus	COSMIC	9.540	Down-regulation
Atypical_PIKK_ATM_ATM_ST	P38398	BRCA1	Q13315	ATM	S1189	P1192S	1192	Missense	distal	3	no	12.539	12.387	EPSD;PhosphoSitePlus	COSMIC	9.540	Down-regulation
Atypical_PIKK_ATM_ATM_ST	P38398	BRCA1	Q13315	ATM	S1189	P1192L	1192	Missense	distal	3	no	12.539	12.669	EPSD;PhosphoSitePlus	COSMIC	9.540	Up-regulation
Atypical_PIKK_ATM_ATM_ST	P38398	BRCA1	Q13315	ATM	S1189	R1188K	1188	Missense	proximal	-1	no	12.539	12.721	EPSD;PhosphoSitePlus	COSMIC	9.540	Up-regulation
Atypical_PIKK_ATM_ATM_ST	P38398	BRCA1	Q13315	ATM	S1191	E1185Q	1185	Missense	distal	-6	no	10.237	10.012	EPSD	COSMIC	9.540	Down-regulation
Atypical_PIKK_ATM_ATM_ST	P38398	BRCA1	Q13315	ATM	S1191	P1190H	1190	Missense	proximal	-1	no	10.237	10.325	EPSD	COSMIC;GDSC;CCLE	9.540	Up-regulation
Atypical_PIKK_ATM_ATM_ST	P38398	BRCA1	Q13315	ATM	S1191	P1190F	1190	Missense	proximal	-1	no	10.237	10.103	EPSD	COSMIC	9.540	Down-regulation
Atypical_PIKK_ATM_ATM_ST	P38398	BRCA1	Q13315	ATM	S1191	P1192F	1192	Missense	proximal	1	no	10.237	4.801	EPSD	COSMIC	9.540	Loss
Atypical_PIKK_ATM_ATM_ST	P38398	BRCA1	Q13315	ATM	S1191	P1190L	1190	Missense	proximal	-1	no	10.237	10.394	EPSD	COSMIC	9.540	Up-regulation
Atypical_PIKK_ATM_ATM_ST	P38398	BRCA1	Q13315	ATM	S1191	P1192S	1192	Missense	proximal	1	no	10.237	3.261	EPSD	COSMIC	9.540	Loss
Atypical_PIKK_ATM_ATM_ST	P38398	BRCA1	Q13315	ATM	S1191	P1192L	1192	Missense	proximal	1	no	10.237	8.682	EPSD	COSMIC	9.540	Loss
Atypical_PIKK_ATM_ATM_ST	P38398	BRCA1	Q13315	ATM	S1191	R1188K	1188	Missense	distal	-3	no	10.237	9.405	EPSD	COSMIC	9.540	Loss
Atypical_PIKK_ATM_ATM_ST	P38398	BRCA1	Q13315	ATM	S1191	H1197Y	1197	Missense	distal	6	no	10.237	10.229	EPSD	COSMIC	9.540	Down-regulation
Atypical_PIKK_ATM_ATM_ST	P38398	BRCA1	Q13315	ATM	S1211	S1212P	1212	Missense	proximal	1	no	2.886	9.862	EPSD	COSMIC	9.540	Gain
Atypical_PIKK_ATM_ATM_ST	P38398	BRCA1	Q13315	ATM	S1212	E1214K	1214	Missense	proximal	2	no	9.588	8.257	EPSD	COSMIC	9.540	Loss
Atypical_PIKK_ATM_ATM_ST	P38398	BRCA1	Q13315	ATM	S1212	K1208T	1208	Missense	distal	-4	no	9.588	9.898	EPSD	COSMIC	9.540	Up-regulation
Atypical_PIKK_ATM_ATM_ST	P38398	BRCA1	Q13315	ATM	S1212	S1212P	1212	Missense	central	0	yes	9.588	0.000	EPSD	COSMIC	9.540	Loss
Atypical_PIKK_ATM_ATM_ST	P38398	BRCA1	Q13315	ATM	S1212	E1210K	1210	Missense	proximal	-2	no	9.588	9.012	EPSD	COSMIC	9.540	Loss
Atypical_PIKK_ATM_ATM_ST	P38398	BRCA1	Q13315	ATM	S1212	K1207T	1207	Missense	distal	-5	no	9.588	9.582	EPSD	COSMIC	9.540	Down-regulation
Atypical_PIKK_ATM_ATM_ST	P38398	BRCA1	Q13315	ATM	S1218	E1214K	1214	Missense	distal	-4	no	10.333	9.361	EPSD	COSMIC	9.540	Loss
Atypical_PIKK_ATM_ATM_ST	P38398	BRCA1	Q13315	ATM	S1218	E1221A	1221	Missense	distal	3	no	10.333	10.565	EPSD	COSMIC	9.540	Up-regulation
Atypical_PIKK_ATM_ATM_ST	P38398	BRCA1	Q13315	ATM	S1218	E1222Q	1222	Missense	distal	4	no	10.333	10.664	EPSD	COSMIC	9.540	Up-regulation
Atypical_PIKK_ATM_ATM_ST	P38398	BRCA1	Q13315	ATM	S1218	P1224H	1224	Missense	distal	6	no	10.333	10.311	EPSD	COSMIC	9.540	Down-regulation
Atypical_PIKK_ATM_ATM_ST	P38398	BRCA1	Q13315	ATM	S1218	S1212P	1212	Missense	distal	-6	no	10.333	10.274	EPSD	COSMIC	9.540	Down-regulation
Atypical_PIKK_ATM_ATM_ST	P38398	BRCA1	Q13315	ATM	S1218	P1224L	1224	Missense	distal	6	no	10.333	10.288	EPSD	COSMIC	9.540	Down-regulation
Atypical_PIKK_ATM_ATM_ST	P38398	BRCA1	Q13315	ATM	S1239	Q1240E	1240	Missense	proximal	1	no	11.480	5.584	EPSD	COSMIC	9.540	Loss
Atypical_PIKK_ATM_ATM_ST	P38398	BRCA1	Q13315	ATM	S1239	S1245N	1245	Missense	distal	6	no	11.480	11.470	EPSD	COSMIC	9.540	Down-regulation
Atypical_PIKK_ATM_ATM_ST	P38398	BRCA1	Q13315	ATM	S1239	H1244Y	1244	Missense	distal	5	no	11.480	11.405	EPSD	COSMIC	9.540	Down-regulation
Atypical_PIKK_ATM_ATM_ST	P38398	BRCA1	Q13315	ATM	S1239	Q1240L	1240	Missense	proximal	1	no	11.480	5.124	EPSD	COSMIC	9.540	Loss
Atypical_PIKK_ATM_ATM_ST	P38398	BRCA1	Q13315	ATM	S1239	S1241F	1241	Missense	proximal	2	no	11.480	10.002	EPSD	COSMIC	9.540	Down-regulation
Atypical_PIKK_ATM_ATM_ST	P38398	BRCA1	Q13315	ATM	S1239	P1238H	1238	Missense	proximal	-1	no	11.480	11.568	EPSD	COSMIC	9.540	Up-regulation
Atypical_PIKK_ATM_ATM_ST	P38398	BRCA1	Q13315	ATM	S1239	T1246A	1246	Missense	distal	7	no	11.480	11.494	EPSD	COSMIC	9.540	Up-regulation
Atypical_PIKK_ATM_ATM_ST	P38398	BRCA1	Q13315	ATM	S1239	I1237L	1237	Missense	proximal	-2	no	11.480	11.780	EPSD	COSMIC	9.540	Up-regulation
Atypical_PIKK_ATM_ATM_ST	P38398	BRCA1	Q13315	ATM	S1239	S1245Y	1245	Missense	distal	6	no	11.480	11.439	EPSD	COSMIC	9.540	Down-regulation
Atypical_PIKK_ATM_ATM_ST	P38398	BRCA1	Q13315	ATM	S1239	S1245A	1245	Missense	distal	6	no	11.480	11.487	EPSD	COSMIC	9.540	Up-regulation
Atypical_PIKK_ATM_ATM_ST	P38398	BRCA1	Q13315	ATM	S1239	S1245F	1245	Missense	distal	6	no	11.480	11.404	EPSD	COSMIC	9.540	Down-regulation
Atypical_PIKK_ATM_ATM_ST	P38398	BRCA1	Q13315	ATM	S1266	L1263F	1263	Missense	distal	-3	no	9.113	9.975	EPSD	COSMIC	9.540	Gain
Atypical_PIKK_ATM_ATM_ST	P38398	BRCA1	Q13315	ATM	S1280	K1278Q	1278	Missense	proximal	-2	no	16.159	16.430	EPSD	COSMIC	9.540	Up-regulation
Atypical_PIKK_ATM_ATM_ST	P38398	BRCA1	Q13315	ATM	S1280	S1286T	1286	Missense	distal	6	no	16.159	16.149	EPSD	COSMIC	9.540	Down-regulation
Atypical_PIKK_ATM_ATM_ST	P38398	BRCA1	Q13315	ATM	S1280	I1275V	1275	Missense	distal	-5	no	16.159	16.158	EPSD	COSMIC	9.540	Down-regulation
Atypical_PIKK_ATM_ATM_ST	P38398	BRCA1	Q13315	ATM	S1280	H1284Y	1284	Missense	distal	4	no	16.159	16.345	EPSD	COSMIC	9.540	Up-regulation
Atypical_PIKK_ATM_ATM_ST	P38398	BRCA1	Q13315	ATM	S1301	E1304V	1304	Missense	distal	3	no	9.238	9.757	EPSD	COSMIC	9.540	Gain
Atypical_PIKK_ATM_ATM_ST	P38398	BRCA1	Q13315	ATM	T1312	P1315S	1315	Missense	distal	3	no	12.945	12.794	EPSD	COSMIC	9.540	Down-regulation
Atypical_PIKK_ATM_ATM_ST	P38398	BRCA1	Q13315	ATM	T1312	A1308S	1308	Missense	distal	-4	no	12.945	13.455	EPSD	COSMIC	9.540	Up-regulation
Atypical_PIKK_ATM_ATM_ST	P38398	BRCA1	Q13315	ATM	T1312	N1309L	1309	Missense	distal	-3	no	12.945	13.181	EPSD	COSMIC	9.540	Up-regulation
Atypical_PIKK_ATM_ATM_ST	P38398	BRCA1	Q13315	ATM	T1312	T1310S	1310	Missense	proximal	-2	no	12.945	13.033	EPSD	COSMIC	9.540	Up-regulation
Atypical_PIKK_ATM_ATM_ST	P38398	BRCA1	Q13315	ATM	S1330	G1332R	1332	Missense	proximal	2	no	14.179	14.040	EPSD	COSMIC	9.540	Down-regulation
Atypical_PIKK_ATM_ATM_ST	P38398	BRCA1	Q13315	ATM	S1387	S1387F	1387	Missense	central	0	yes	16.646	0.000	EPSD;PhosphoSitePlus	COSMIC	9.540	Loss
Atypical_PIKK_ATM_ATM_ST	P38398	BRCA1	Q13315	ATM	S1387	G1384W	1384	Missense	distal	-3	no	16.646	16.678	EPSD;PhosphoSitePlus	COSMIC	9.540	Up-regulation
Atypical_PIKK_ATM_ATM_ST	P38398	BRCA1	Q13315	ATM	S1387	T1393N	1393	Missense	distal	6	no	16.646	16.645	EPSD;PhosphoSitePlus	COSMIC	9.540	Down-regulation
Atypical_PIKK_ATM_ATM_ST	P38398	BRCA1	Q13315	ATM	S1387	Q1388E	1388	Missense	proximal	1	no	16.646	10.749	EPSD;PhosphoSitePlus	COSMIC	9.540	Down-regulation
Atypical_PIKK_ATM_ATM_ST	P38398	BRCA1	Q13315	ATM	S1387	Q1388H	1388	Missense	proximal	1	no	16.646	1.737	EPSD;PhosphoSitePlus	COSMIC	9.540	Loss
Atypical_PIKK_ATM_ATM_ST	P38398	BRCA1	Q13315	ATM	S1387	T1394I	1394	Missense	distal	7	no	16.646	16.661	EPSD;PhosphoSitePlus	COSMIC;CCLE	9.540	Up-regulation
Atypical_PIKK_ATM_ATM_ST	P38398	BRCA1	Q13315	ATM	S1387	L1392F	1392	Missense	distal	5	no	16.646	16.788	EPSD;PhosphoSitePlus	COSMIC	9.540	Up-regulation
Atypical_PIKK_ATM_ATM_ST	P38398	BRCA1	Q13315	ATM	S1387	S1387N	1387	Missense	central	0	yes	16.646	0.000	EPSD;PhosphoSitePlus	COSMIC	9.540	Loss
Atypical_PIKK_ATM_ATM_ST	P38398	BRCA1	Q13315	ATM	T1394	S1387F	1387	Missense	distal	-7	no	13.113	12.284	EPSD	COSMIC	9.540	Down-regulation
Atypical_PIKK_ATM_ATM_ST	P38398	BRCA1	Q13315	ATM	T1394	Q1396H	1396	Missense	proximal	2	no	13.113	12.734	EPSD	COSMIC	9.540	Down-regulation
Atypical_PIKK_ATM_ATM_ST	P38398	BRCA1	Q13315	ATM	T1394	T1393N	1393	Missense	proximal	-1	no	13.113	13.048	EPSD	COSMIC	9.540	Down-regulation
Atypical_PIKK_ATM_ATM_ST	P38398	BRCA1	Q13315	ATM	T1394	Q1388E	1388	Missense	distal	-6	no	13.113	13.337	EPSD	COSMIC	9.540	Up-regulation
Atypical_PIKK_ATM_ATM_ST	P38398	BRCA1	Q13315	ATM	T1394	Q1395E	1395	Missense	proximal	1	no	13.113	7.216	EPSD	COSMIC	9.540	Loss
Atypical_PIKK_ATM_ATM_ST	P38398	BRCA1	Q13315	ATM	T1394	Q1388H	1388	Missense	distal	-6	no	13.113	12.971	EPSD	COSMIC	9.540	Down-regulation
Atypical_PIKK_ATM_ATM_ST	P38398	BRCA1	Q13315	ATM	T1394	T1394I	1394	Missense	central	0	yes	13.113	0.000	EPSD	COSMIC;CCLE	9.540	Loss
Atypical_PIKK_ATM_ATM_ST	P38398	BRCA1	Q13315	ATM	T1394	L1392F	1392	Missense	proximal	-2	no	13.113	12.602	EPSD	COSMIC	9.540	Down-regulation
Atypical_PIKK_ATM_ATM_ST	P38398	BRCA1	Q13315	ATM	T1394	S1387N	1387	Missense	distal	-7	no	13.113	12.927	EPSD	COSMIC	9.540	Down-regulation
Atypical_PIKK_ATM_ATM_ST	P38398	BRCA1	Q13315	ATM	S1423	E1419G	1419	Missense	distal	-4	no	14.237	13.171	EPSD;PhosphoSitePlus	COSMIC	9.540	Down-regulation
Atypical_PIKK_ATM_ATM_ST	P38398	BRCA1	Q13315	ATM	S1423	S1423R	1423	Missense	central	0	yes	14.237	0.000	EPSD;PhosphoSitePlus	COSMIC	9.540	Loss
Atypical_PIKK_ATM_ATM_ST	P38398	BRCA1	Q13315	ATM	S1423	S1426C	1426	Missense	distal	3	no	14.237	14.659	EPSD;PhosphoSitePlus	COSMIC	9.540	Up-regulation
Atypical_PIKK_ATM_ATM_ST	P38398	BRCA1	Q13315	ATM	S1423	S1426F	1426	Missense	distal	3	no	14.237	14.819	EPSD;PhosphoSitePlus	COSMIC	9.540	Up-regulation
Atypical_PIKK_ATM_ATM_ST	P38398	BRCA1	Q13315	ATM	S1423	S1426Y	1426	Missense	distal	3	no	14.237	14.479	EPSD;PhosphoSitePlus	COSMIC	9.540	Up-regulation
Atypical_PIKK_ATM_ATM_ST	P38398	BRCA1	Q13315	ATM	S1457	S1450P	1450	Missense	distal	-7	no	14.423	14.187	PhosphoSitePlus;EPSD	COSMIC	9.540	Down-regulation
Atypical_PIKK_ATM_ATM_ST	P38398	BRCA1	Q13315	ATM	S1466	G1471R	1471	Missense	distal	5	no	15.773	15.760	EPSD	COSMIC	9.540	Down-regulation
Atypical_PIKK_ATM_ATM_ST	P38398	BRCA1	Q13315	ATM	S1466	S1466C	1466	Missense	central	0	yes	15.773	0.000	EPSD	COSMIC	9.540	Loss
Atypical_PIKK_ATM_ATM_ST	P38398	BRCA1	Q13315	ATM	S1466	S1473Y	1473	Missense	distal	7	no	15.773	15.806	EPSD	COSMIC	9.540	Up-regulation
Atypical_PIKK_ATM_ATM_ST	P38398	BRCA1	Q13315	ATM	S1466	S1473F	1473	Missense	distal	7	no	15.773	15.833	EPSD	COSMIC	9.540	Up-regulation
Atypical_PIKK_ATM_ATM_ST	P38398	BRCA1	Q13315	ATM	S1466	S1466I	1466	Missense	central	0	yes	15.773	0.000	EPSD	COSMIC	9.540	Loss
Atypical_PIKK_ATM_ATM_ST	P38398	BRCA1	Q13315	ATM	S1486	P1491L	1491	Missense	distal	5	no	10.008	9.991	EPSD	COSMIC	9.540	Down-regulation
Atypical_PIKK_ATM_ATM_ST	P38398	BRCA1	Q13315	ATM	S1486	S1483C	1483	Missense	distal	-3	no	10.008	10.176	EPSD	COSMIC	9.540	Up-regulation
Atypical_PIKK_ATM_ATM_ST	P38398	BRCA1	Q13315	ATM	S1486	E1490Q	1490	Missense	distal	4	no	10.008	10.339	EPSD	COSMIC	9.540	Up-regulation
Atypical_PIKK_ATM_ATM_ST	P38398	BRCA1	Q13315	ATM	S1486	V1493E	1493	Missense	distal	7	no	10.008	9.956	EPSD	COSMIC	9.540	Down-regulation
Atypical_PIKK_ATM_ATM_ST	P38398	BRCA1	Q13315	ATM	S1486	T1485S	1485	Missense	proximal	-1	no	10.008	9.998	EPSD	COSMIC	9.540	Down-regulation
Atypical_PIKK_ATM_ATM_ST	P38398	BRCA1	Q13315	ATM	S1486	N1488S	1488	Missense	proximal	2	no	10.008	10.649	EPSD	COSMIC	9.540	Up-regulation
Atypical_PIKK_ATM_ATM_ST	P38398	BRCA1	Q13315	ATM	S1497	P1491L	1491	Missense	distal	-6	no	12.560	12.331	EPSD;PhosphoSitePlus	COSMIC	9.540	Down-regulation
Atypical_PIKK_ATM_ATM_ST	P38398	BRCA1	Q13315	ATM	S1497	P1502L	1502	Missense	distal	5	no	12.560	12.543	EPSD;PhosphoSitePlus	COSMIC	9.540	Down-regulation
Atypical_PIKK_ATM_ATM_ST	P38398	BRCA1	Q13315	ATM	S1497	S1499F	1499	Missense	proximal	2	no	12.560	11.082	EPSD;PhosphoSitePlus	COSMIC	9.540	Down-regulation
Atypical_PIKK_ATM_ATM_ST	P38398	BRCA1	Q13315	ATM	S1497	E1490Q	1490	Missense	distal	-7	no	12.560	12.005	EPSD;PhosphoSitePlus	COSMIC	9.540	Down-regulation
Atypical_PIKK_ATM_ATM_ST	P38398	BRCA1	Q13315	ATM	S1497	S1497P	1497	Missense	central	0	yes	12.560	0.000	EPSD;PhosphoSitePlus	COSMIC	9.540	Loss
Atypical_PIKK_ATM_ATM_ST	P38398	BRCA1	Q13315	ATM	S1497	V1493E	1493	Missense	distal	-4	no	12.560	13.828	EPSD;PhosphoSitePlus	COSMIC	9.540	Up-regulation
Atypical_PIKK_ATM_ATM_ST	P38398	BRCA1	Q13315	ATM	S1516	G1515E	1515	Missense	proximal	-1	no	9.248	9.650	EPSD	COSMIC	9.540	Gain
Atypical_PIKK_ATM_ATM_ST	P38398	BRCA1	Q13315	ATM	S1516	L1517P	1517	Missense	proximal	1	no	9.248	10.803	EPSD	COSMIC	9.540	Gain
Atypical_PIKK_ATM_ATM_ST	P38398	BRCA1	Q13315	ATM	S1524	Q1525H	1525	Missense	proximal	1	no	14.600	-0.309	EPSD;PhosphoSitePlus	COSMIC	9.540	Loss
Atypical_PIKK_ATM_ATM_ST	P38398	BRCA1	Q13315	ATM	S1524	K1530R	1530	Missense	distal	6	no	14.600	14.604	EPSD;PhosphoSitePlus	COSMIC	9.540	Up-regulation
Atypical_PIKK_ATM_ATM_ST	P38398	BRCA1	Q13315	ATM	S1524	N1519S	1519	Missense	distal	-5	no	14.600	14.628	EPSD;PhosphoSitePlus	COSMIC	9.540	Up-regulation
Atypical_PIKK_ATM_ATM_ST	P38398	BRCA1	Q13315	ATM	S1524	E1527D	1527	Missense	distal	3	no	14.600	14.960	EPSD;PhosphoSitePlus	COSMIC	9.540	Up-regulation
Atypical_PIKK_ATM_ATM_ST	P38398	BRCA1	Q13315	ATM	S1524	L1517V	1517	Missense	distal	-7	no	14.600	14.708	EPSD;PhosphoSitePlus	COSMIC	9.540	Up-regulation
Atypical_PIKK_ATM_ATM_ST	P38398	BRCA1	Q13315	ATM	S1524	L1517P	1517	Missense	distal	-7	no	14.600	14.952	EPSD;PhosphoSitePlus	COSMIC	9.540	Up-regulation
Atypical_PIKK_ATM_ATM_ST	P38398	BRCA1	Q13315	ATM	S1524	P1523L	1523	Missense	proximal	-1	no	14.600	14.758	EPSD;PhosphoSitePlus	COSMIC	9.540	Up-regulation
Atypical_PIKK_ATM_ATM_ST	P38398	BRCA1	Q13315	ATM	S1542	D1546Y	1546	Missense	distal	4	no	12.092	12.187	EPSD;PhosphoSitePlus	COSMIC	9.540	Up-regulation
Atypical_PIKK_ATM_ATM_ST	P38398	BRCA1	Q13315	ATM	S1542	E1540K	1540	Missense	proximal	-2	no	12.092	11.516	EPSD;PhosphoSitePlus	COSMIC	9.540	Down-regulation
Atypical_PIKK_ATM_ATM_ST	P38398	BRCA1	Q13315	ATM	S1542	D1546N	1546	Missense	distal	4	no	12.092	12.011	EPSD;PhosphoSitePlus	COSMIC;GDSC	9.540	Down-regulation
Atypical_PIKK_ATM_ATM_ST	P38398	BRCA1	Q13315	ATM	S1542	T1548M	1548	Missense	distal	6	no	12.092	12.072	EPSD;PhosphoSitePlus	COSMIC;GDSC;CCLE	9.540	Down-regulation
Atypical_PIKK_ATM_ATM_ST	P38398	BRCA1	Q13315	ATM	S1542	E1536K	1536	Missense	distal	-6	no	12.092	11.791	EPSD;PhosphoSitePlus	COSMIC	9.540	Down-regulation
Atypical_PIKK_ATM_ATM_ST	P38398	BRCA1	Q13315	ATM	S1542	L1547F	1547	Missense	distal	5	no	12.092	12.233	EPSD;PhosphoSitePlus	COSMIC	9.540	Up-regulation
Atypical_PIKK_ATM_ATM_ST	P38398	BRCA1	Q13315	ATM	S1542	G1543V	1543	Missense	proximal	1	no	12.092	5.571	EPSD;PhosphoSitePlus	COSMIC	9.540	Loss
Atypical_PIKK_ATM_ATM_ST	P38398	BRCA1	Q13315	ATM	S1572	I1568S	1568	Missense	distal	-4	no	9.246	9.957	EPSD	COSMIC	9.540	Gain
Atypical_PIKK_ATM_ATM_ST	P38398	BRCA1	Q13315	ATM	S1613	V1607E	1607	Missense	distal	-6	no	9.447	9.891	EPSD	COSMIC	9.540	Gain
Atypical_PIKK_ATM_ATM_ST	P38398	BRCA1	Q13315	ATM	T1658	P1659Q	1659	Missense	proximal	1	no	8.422	13.224	EPSD	COSMIC	9.540	Gain
Atypical_PIKK_ATM_ATM_ST	P38398	BRCA1	Q13315	ATM	T1658	V1654E	1654	Missense	distal	-4	no	8.422	9.690	EPSD	COSMIC	9.540	Gain
Atypical_PIKK_ATM_ATM_ST	P38398	BRCA1	Q13315	ATM	T1720	Q1721R	1721	Missense	proximal	1	no	11.719	5.068	EPSD	COSMIC	9.540	Loss
Atypical_PIKK_ATM_ATM_ST	P38398	BRCA1	Q13315	ATM	T1720	T1720I	1720	Missense	central	0	yes	11.719	0.000	EPSD	COSMIC	9.540	Loss
Atypical_PIKK_ATM_ATM_ST	P38398	BRCA1	Q13315	ATM	T1720	S1722F	1722	Missense	proximal	2	no	11.719	10.241	EPSD	COSMIC	9.540	Down-regulation
Atypical_PIKK_ATM_ATM_ST	P38398	BRCA1	Q13315	ATM	T1720	R1726T	1726	Missense	distal	6	no	11.719	11.727	EPSD	COSMIC	9.540	Up-regulation
Atypical_PIKK_ATM_ATM_ST	P38398	BRCA1	Q13315	ATM	T1720	W1718L	1718	Missense	proximal	-2	no	11.719	11.824	EPSD	COSMIC	9.540	Up-regulation
Atypical_PIKK_ATM_ATM_ST	P38398	BRCA1	Q13315	ATM	T1720	I1723V	1723	Missense	distal	3	no	11.719	11.562	EPSD	COSMIC	9.540	Down-regulation
Atypical_PIKK_ATM_ATM_ST	P38398	BRCA1	Q13315	ATM	T1720	V1713A	1713	Missense	distal	-7	no	11.719	12.103	EPSD	COSMIC	9.540	Up-regulation
Atypical_PIKK_ATM_ATM_ST	P38398	BRCA1	Q13315	ATM	T1720	T1720A	1720	Missense	central	0	yes	11.719	0.000	EPSD	COSMIC	9.540	Loss
Atypical_PIKK_ATM_ATM_ST	P38398	BRCA1	Q13315	ATM	T1720	V1719M	1719	Missense	proximal	-1	no	11.719	11.852	EPSD	COSMIC	9.540	Up-regulation
Atypical_PIKK_ATM_ATM_ST	P38398	BRCA1	Q13315	ATM	T1720	E1725K	1725	Missense	distal	5	no	11.719	11.894	EPSD	COSMIC	9.540	Up-regulation
Atypical_PIKK_ATM_ATM_ST	Q96KQ7	EHMT2	Q13315	ATM	T55	S58F	58	Missense	distal	3	no	9.122	9.704	EPSD	COSMIC	9.540	Gain
Atypical_PIKK_ATM_ATM_ST	Q96KQ7	EHMT2	Q13315	ATM	S66	A62V	62	Missense	distal	-4	no	10.599	10.119	EPSD	COSMIC	9.540	Down-regulation
Atypical_PIKK_ATM_ATM_ST	Q96KQ7	EHMT2	Q13315	ATM	S66	P67Q	67	Missense	proximal	1	no	10.599	15.401	EPSD	COSMIC	9.540	Up-regulation
Atypical_PIKK_ATM_ATM_ST	Q96KQ7	EHMT2	Q13315	ATM	S66	P61S	61	Missense	distal	-5	no	10.599	10.595	EPSD	COSMIC	9.540	Down-regulation
Atypical_PIKK_ATM_ATM_ST	Q96KQ7	EHMT2	Q13315	ATM	S119	T113K	113	Missense	distal	-6	no	11.251	11.206	EPSD	COSMIC	9.540	Down-regulation
Atypical_PIKK_ATM_ATM_ST	Q96KQ7	EHMT2	Q13315	ATM	S119	S119F	119	Missense	central	0	yes	11.251	0.000	EPSD	COSMIC	9.540	Loss
Atypical_PIKK_ATM_ATM_ST	Q96KQ7	EHMT2	Q13315	ATM	S119	S121R	121	Missense	proximal	2	no	11.251	10.253	EPSD	COSMIC	9.540	Down-regulation
Atypical_PIKK_ATM_ATM_ST	Q96KQ7	EHMT2	Q13315	ATM	S119	S115F	115	Missense	distal	-4	no	11.251	9.852	EPSD	COSMIC	9.540	Down-regulation
Atypical_PIKK_ATM_ATM_ST	Q96KQ7	EHMT2	Q13315	ATM	S128	R129Q	129	Missense	proximal	1	no	6.635	13.286	EPSD	COSMIC	9.540	Gain
Atypical_PIKK_ATM_ATM_ST	Q96KQ7	EHMT2	Q13315	ATM	S173	P169Q	169	Missense	distal	-4	no	10.012	10.237	EPSD	COSMIC	9.540	Up-regulation
Atypical_PIKK_ATM_ATM_ST	Q96KQ7	EHMT2	Q13315	ATM	S173	P178T	178	Missense	distal	5	no	10.012	9.814	EPSD	COSMIC	9.540	Down-regulation
Atypical_PIKK_ATM_ATM_ST	Q96KQ7	EHMT2	Q13315	ATM	S173	T171A	171	Missense	proximal	-2	no	10.012	9.913	EPSD	COSMIC	9.540	Down-regulation
Atypical_PIKK_ATM_ATM_ST	Q96KQ7	EHMT2	Q13315	ATM	S327	S327L	327	Missense	central	0	yes	11.426	0.000	EPSD	COSMIC	9.540	Loss
Atypical_PIKK_ATM_ATM_ST	Q96KQ7	EHMT2	Q13315	ATM	S327	D332N	332	Missense	distal	5	no	11.426	11.315	EPSD	COSMIC	9.540	Down-regulation
Atypical_PIKK_ATM_ATM_ST	Q96KQ7	EHMT2	Q13315	ATM	S327	E326A	326	Missense	proximal	-1	no	11.426	11.056	EPSD	COSMIC	9.540	Down-regulation
Atypical_PIKK_ATM_ATM_ST	Q96KQ7	EHMT2	Q13315	ATM	S327	D332A	332	Missense	distal	5	no	11.426	11.388	EPSD	COSMIC	9.540	Down-regulation
Atypical_PIKK_ATM_ATM_ST	Q96KQ7	EHMT2	Q13315	ATM	S331	S327L	327	Missense	distal	-4	no	9.788	8.849	EPSD	COSMIC	9.540	Loss
Atypical_PIKK_ATM_ATM_ST	Q96KQ7	EHMT2	Q13315	ATM	S331	D332N	332	Missense	proximal	1	no	9.788	5.958	EPSD	COSMIC	9.540	Loss
Atypical_PIKK_ATM_ATM_ST	Q96KQ7	EHMT2	Q13315	ATM	S331	E326A	326	Missense	distal	-5	no	9.788	9.946	EPSD	COSMIC	9.540	Up-regulation
Atypical_PIKK_ATM_ATM_ST	Q96KQ7	EHMT2	Q13315	ATM	S331	D332A	332	Missense	proximal	1	no	9.788	8.946	EPSD	COSMIC	9.540	Loss
Atypical_PIKK_ATM_ATM_ST	P23919	DTYMK	Q13315	ATM	S88	T92I	92	Missense	distal	4	no	12.473	13.048	PhosphoSitePlus	COSMIC	9.540	Up-regulation
Atypical_PIKK_ATM_ATM_ST	P23919	DTYMK	Q13315	ATM	S88	L82V	82	Missense	distal	-6	no	12.473	12.504	PhosphoSitePlus	COSMIC	9.540	Up-regulation
Atypical_PIKK_ATM_ATM_ST	P23919	DTYMK	Q13315	ATM	S88	L82I	82	Missense	distal	-6	no	12.473	12.360	PhosphoSitePlus	COSMIC;GDSC	9.540	Down-regulation
Atypical_PIKK_ATM_ATM_ST	P23919	DTYMK	Q13315	ATM	S88	P81Q	81	Missense	distal	-7	no	12.473	12.510	PhosphoSitePlus	COSMIC	9.540	Up-regulation
Atypical_PIKK_ATM_ATM_ST	Q8NHY2	COP1	Q13315	ATM	S108	G101D	101	Missense	distal	-7	no	9.592	9.882	EPSD	COSMIC	9.540	Up-regulation
Atypical_PIKK_ATM_ATM_ST	Q8NHY2	COP1	Q13315	ATM	S108	G109S	109	Missense	proximal	1	no	9.592	4.288	EPSD	COSMIC	9.540	Loss
Atypical_PIKK_ATM_ATM_ST	Q8NHY2	COP1	Q13315	ATM	S108	S110N	110	Missense	proximal	2	no	9.592	8.950	EPSD	COSMIC	9.540	Loss
Atypical_PIKK_ATM_ATM_ST	Q8NHY2	COP1	Q13315	ATM	S108	S102N	102	Missense	distal	-6	no	9.592	9.476	EPSD	COSMIC	9.540	Loss
Atypical_PIKK_ATM_ATM_ST	Q8NHY2	COP1	Q13315	ATM	S108	S105G	105	Missense	distal	-3	no	9.592	9.870	EPSD	COSMIC	9.540	Up-regulation
Atypical_PIKK_ATM_ATM_ST	Q8NHY2	COP1	Q13315	ATM	S108	R111V	111	Missense	distal	3	no	9.592	9.750	EPSD	COSMIC	9.540	Up-regulation
Atypical_PIKK_ATM_ATM_ST	Q8NHY2	COP1	Q13315	ATM	S108	S103C	103	Missense	distal	-5	no	9.592	9.685	EPSD	COSMIC;GDSC	9.540	Up-regulation
Atypical_PIKK_ATM_ATM_ST	Q8NHY2	COP1	Q13315	ATM	S332	P334L	334	Missense	proximal	2	no	16.323	15.534	EPSD	COSMIC	9.540	Down-regulation
Atypical_PIKK_ATM_ATM_ST	Q8NHY2	COP1	Q13315	ATM	S332	T329A	329	Missense	distal	-3	no	16.323	15.945	EPSD	COSMIC	9.540	Down-regulation
Atypical_PIKK_ATM_ATM_ST	Q8NHY2	COP1	Q13315	ATM	S332	G339D	339	Missense	distal	7	no	16.323	16.290	EPSD	COSMIC	9.540	Down-regulation
Atypical_PIKK_ATM_ATM_ST	Q8NHY2	COP1	Q13315	ATM	S332	I325V	325	Missense	distal	-7	no	16.323	16.507	EPSD	COSMIC	9.540	Up-regulation
Atypical_PIKK_ATM_ATM_ST	Q8NHY2	COP1	Q13315	ATM	S332	G336C	336	Missense	distal	4	no	16.323	16.703	EPSD	COSMIC	9.540	Up-regulation
Atypical_PIKK_ATM_ATM_ST	Q8NHY2	COP1	Q13315	ATM	S332	D327N	327	Missense	distal	-5	no	16.323	16.506	EPSD	COSMIC	9.540	Up-regulation
Atypical_PIKK_ATM_ATM_ST	Q8NHY2	COP1	Q13315	ATM	S332	F337L	337	Missense	distal	5	no	16.323	16.181	EPSD	COSMIC	9.540	Down-regulation
Atypical_PIKK_ATM_ATM_ST	Q8NHY2	COP1	Q13315	ATM	S387	S380L	380	Missense	distal	-7	no	14.681	14.094	PhosphoSitePlus	COSMIC	9.540	Down-regulation
Atypical_PIKK_ATM_ATM_ST	Q8NHY2	COP1	Q13315	ATM	S387	R384Q	384	Missense	distal	-3	no	14.681	13.906	PhosphoSitePlus	COSMIC	9.540	Down-regulation
Atypical_PIKK_ATM_ATM_ST	Q8NHY2	COP1	Q13315	ATM	S387	R384L	384	Missense	distal	-3	no	14.681	14.150	PhosphoSitePlus	COSMIC	9.540	Down-regulation
Atypical_PIKK_ATM_ATM_ST	Q8NHY2	COP1	Q13315	ATM	S387	E394K	394	Missense	distal	7	no	14.681	14.708	PhosphoSitePlus	COSMIC	9.540	Up-regulation
Atypical_PIKK_ATM_ATM_ST	Q8NHY2	COP1	Q13315	ATM	S387	Q388E	388	Missense	proximal	1	no	14.681	8.785	PhosphoSitePlus	COSMIC	9.540	Loss
Atypical_PIKK_ATM_ATM_ST	Q8NHY2	COP1	Q13315	ATM	S387	Q393L	393	Missense	distal	6	no	14.681	14.647	PhosphoSitePlus	COSMIC	9.540	Down-regulation
Atypical_PIKK_ATM_ATM_ST	Q8NHY2	COP1	Q13315	ATM	S387	S383G	383	Missense	distal	-4	no	14.681	13.893	PhosphoSitePlus	COSMIC	9.540	Down-regulation
Atypical_PIKK_ATM_ATM_ST	Q8NHY2	COP1	Q13315	ATM	S721	G723C	723	Missense	proximal	2	no	12.496	12.100	EPSD	COSMIC	9.540	Down-regulation
Atypical_PIKK_ATM_ATM_ST	Q8NHY2	COP1	Q13315	ATM	S721	T724I	724	Missense	distal	3	no	12.496	12.917	EPSD	COSMIC	9.540	Up-regulation
Atypical_PIKK_ATM_ATM_ST	Q8NHY2	COP1	Q13315	ATM	S721	A719T	719	Missense	proximal	-2	no	12.496	12.596	EPSD	COSMIC	9.540	Up-regulation
Atypical_PIKK_ATM_ATM_ST	Q8NHY2	COP1	Q13315	ATM	S721	Q722P	722	Missense	proximal	1	no	12.496	7.694	EPSD	COSMIC	9.540	Loss
Atypical_PIKK_ATM_ATM_ST	Q8NHY2	COP1	Q13315	ATM	S721	K726N	726	Missense	distal	5	no	12.496	12.467	EPSD	COSMIC	9.540	Down-regulation
Atypical_PIKK_ATM_ATM_ST	Q8NHY2	COP1	Q13315	ATM	S721	Q722L	722	Missense	proximal	1	no	12.496	6.139	EPSD	COSMIC	9.540	Loss
Atypical_PIKK_ATM_ATM_ST	Q99708	RBBP8	Q13315	ATM	T271	S276N	276	Missense	distal	5	no	15.474	15.448	EPSD	COSMIC	9.540	Down-regulation
Atypical_PIKK_ATM_ATM_ST	Q99708	RBBP8	Q13315	ATM	S276	S276N	276	Missense	central	0	yes	10.302	0.000	EPSD	COSMIC	9.540	Loss
Atypical_PIKK_ATM_ATM_ST	Q99708	RBBP8	Q13315	ATM	S327	P322H	322	Missense	distal	-5	no	10.777	10.821	EPSD	COSMIC	9.540	Up-regulation
Atypical_PIKK_ATM_ATM_ST	Q99708	RBBP8	Q13315	ATM	S327	G331V	331	Missense	distal	4	no	10.777	10.953	EPSD	COSMIC	9.540	Up-regulation
Atypical_PIKK_ATM_ATM_ST	Q99708	RBBP8	Q13315	ATM	S327	E320K	320	Missense	distal	-7	no	10.777	10.108	EPSD	COSMIC;GDSC;CCLE	9.540	Down-regulation
Atypical_PIKK_ATM_ATM_ST	Q99708	RBBP8	Q13315	ATM	S379	A383S	383	Missense	distal	4	no	10.725	11.072	EPSD	COSMIC	9.540	Up-regulation
Atypical_PIKK_ATM_ATM_ST	Q99708	RBBP8	Q13315	ATM	S439	G441E	441	Missense	proximal	2	no	8.662	10.031	EPSD	COSMIC;GDSC;CCLE	9.540	Gain
Atypical_PIKK_ATM_ATM_ST	Q99708	RBBP8	Q13315	ATM	S539	P546S	546	Missense	distal	7	no	10.074	10.056	EPSD	COSMIC	9.540	Down-regulation
Atypical_PIKK_ATM_ATM_ST	Q99708	RBBP8	Q13315	ATM	S549	E552Q	552	Missense	distal	3	no	9.375	9.634	EPSD	COSMIC	9.540	Gain
Atypical_PIKK_ATM_ATM_ST	Q99708	RBBP8	Q13315	ATM	S549	E552D	552	Missense	distal	3	no	9.375	9.734	EPSD	COSMIC	9.540	Gain
Atypical_PIKK_ATM_ATM_ST	Q99708	RBBP8	Q13315	ATM	S555	E552Q	552	Missense	distal	-3	no	16.693	16.817	EPSD	COSMIC	9.540	Up-regulation
Atypical_PIKK_ATM_ATM_ST	Q99708	RBBP8	Q13315	ATM	S555	E552D	552	Missense	distal	-3	no	16.693	17.098	EPSD	COSMIC	9.540	Up-regulation
Atypical_PIKK_ATM_ATM_ST	Q99708	RBBP8	Q13315	ATM	S568	L564F	564	Missense	distal	-4	no	11.175	10.715	EPSD	COSMIC	9.540	Down-regulation
Atypical_PIKK_ATM_ATM_ST	Q99708	RBBP8	Q13315	ATM	S664	D662H	662	Missense	proximal	-2	no	13.382	13.253	EPSD;PhosphoSitePlus	COSMIC	9.540	Down-regulation
Atypical_PIKK_ATM_ATM_ST	Q99708	RBBP8	Q13315	ATM	S723	R730W	730	Missense	distal	7	no	10.530	10.556	EPSD	COSMIC	9.540	Up-regulation
Atypical_PIKK_ATM_ATM_ST	Q99708	RBBP8	Q13315	ATM	S745	D742N	742	Missense	distal	-3	no	14.380	14.107	PhosphoSitePlus;EPSD	COSMIC	9.540	Down-regulation
Atypical_PIKK_ATM_ATM_ST	Q99708	RBBP8	Q13315	ATM	S745	S745C	745	Missense	central	0	yes	14.380	0.000	PhosphoSitePlus;EPSD	COSMIC	9.540	Loss
Atypical_PIKK_ATM_ATM_ST	Q99708	RBBP8	Q13315	ATM	S789	S789C	789	Missense	central	0	yes	9.823	0.000	EPSD	COSMIC	9.540	Loss
Atypical_PIKK_ATM_ATM_ST	Q99708	RBBP8	Q13315	ATM	S789	P794S	794	Missense	distal	5	no	9.823	9.642	EPSD	COSMIC	9.540	Down-regulation
Atypical_PIKK_ATM_ATM_ST	Q99708	RBBP8	Q13315	ATM	T847	P844S	844	Missense	distal	-3	no	12.166	11.970	EPSD	COSMIC	9.540	Down-regulation
Atypical_PIKK_ATM_ATM_ST	O75150	RNF40	Q13315	ATM	S114	A107G	107	Missense	distal	-7	no	14.381	13.965	EPSD;PhosphoSitePlus	COSMIC	9.540	Down-regulation
Atypical_PIKK_ATM_ATM_ST	O75150	RNF40	Q13315	ATM	S819	S819F	819	Missense	central	0	yes	14.389	0.000	EPSD;PhosphoSitePlus	COSMIC	9.540	Loss
Atypical_PIKK_ATM_ATM_ST	Q5VTR2	RNF20	Q13315	ATM	S28	G29R	29	Missense	proximal	1	no	9.751	9.573	EPSD	COSMIC;GDSC;CCLE	9.540	Down-regulation
Atypical_PIKK_ATM_ATM_ST	Q5VTR2	RNF20	Q13315	ATM	S172	R177C	177	Missense	distal	5	no	14.364	14.425	EPSD;PhosphoSitePlus	COSMIC	9.540	Up-regulation
Atypical_PIKK_ATM_ATM_ST	Q5VTR2	RNF20	Q13315	ATM	S203	R204Q	204	Missense	proximal	1	no	7.786	14.438	EPSD	COSMIC	9.540	Gain
Atypical_PIKK_ATM_ATM_ST	Q5VTR2	RNF20	Q13315	ATM	S208	R204Q	204	Missense	distal	-4	no	9.201	9.567	EPSD	COSMIC	9.540	Gain
Atypical_PIKK_ATM_ATM_ST	Q5VTR2	RNF20	Q13315	ATM	S262	V257L	257	Missense	distal	-5	no	10.393	10.303	EPSD	COSMIC	9.540	Down-regulation
Atypical_PIKK_ATM_ATM_ST	Q5VTR2	RNF20	Q13315	ATM	S522	S522P	522	Missense	central	0	yes	15.545	0.000	EPSD;PhosphoSitePlus	COSMIC	9.540	Loss
Atypical_PIKK_ATM_ATM_ST	Q5VTR2	RNF20	Q13315	ATM	S540	S544F	544	Missense	distal	4	no	9.612	10.440	EPSD	COSMIC	9.540	Up-regulation
Atypical_PIKK_ATM_ATM_ST	Q5VTR2	RNF20	Q13315	ATM	S540	S540F	540	Missense	central	0	yes	9.612	0.000	EPSD	COSMIC	9.540	Loss
Atypical_PIKK_ATM_ATM_ST	Q5VTR2	RNF20	Q13315	ATM	S540	L543V	543	Missense	distal	3	no	9.612	9.674	EPSD	COSMIC	9.540	Up-regulation
Atypical_PIKK_ATM_ATM_ST	Q5VTR2	RNF20	Q13315	ATM	S545	S544F	544	Missense	proximal	-1	no	16.618	16.191	PhosphoSitePlus;EPSD	COSMIC	9.540	Down-regulation
Atypical_PIKK_ATM_ATM_ST	Q5VTR2	RNF20	Q13315	ATM	S545	S540F	540	Missense	distal	-5	no	16.618	16.941	PhosphoSitePlus;EPSD	COSMIC	9.540	Up-regulation
Atypical_PIKK_ATM_ATM_ST	Q5VTR2	RNF20	Q13315	ATM	S545	L543V	543	Missense	proximal	-2	no	16.618	16.343	PhosphoSitePlus;EPSD	COSMIC	9.540	Down-regulation
Atypical_PIKK_ATM_ATM_ST	P14618	PKM	Q13315	ATM	T15	A20T	20	Missense	distal	5	no	15.755	15.691	EPSD	COSMIC	9.540	Down-regulation
Atypical_PIKK_ATM_ATM_ST	P14618	PKM	Q13315	ATM	T15	A11V	11	Missense	distal	-4	no	15.755	15.276	EPSD	COSMIC	9.540	Down-regulation
Atypical_PIKK_ATM_ATM_ST	P14618	PKM	Q13315	ATM	T15	G9R	9	Missense	distal	-6	no	15.755	15.777	EPSD	COSMIC	9.540	Up-regulation
Atypical_PIKK_ATM_ATM_ST	P14618	PKM	Q13315	ATM	T15	Q14H	14	Missense	proximal	-1	no	15.755	15.618	EPSD	COSMIC	9.540	Down-regulation
Atypical_PIKK_ATM_ATM_ST	P14618	PKM	Q13315	ATM	T454	R455Q	455	Missense	proximal	1	no	6.441	13.093	EPSD	COSMIC	9.540	Gain
Atypical_PIKK_ATM_ATM_ST	O15355	PPM1G	Q13315	ATM	S183	G182V	182	Missense	proximal	-1	no	14.208	13.976	PhosphoSitePlus	COSMIC	9.540	Down-regulation
Atypical_PIKK_ATM_ATM_ST	O15355	PPM1G	Q13315	ATM	S201	S201P	201	Missense	central	0	yes	14.556	0.000	EPSD	COSMIC	9.540	Loss
Atypical_PIKK_ATM_ATM_ST	O15355	PPM1G	Q13315	ATM	S325	P323A	323	Missense	proximal	-2	no	9.571	9.620	EPSD	COSMIC	9.540	Up-regulation
Atypical_PIKK_ATM_ATM_ST	O15355	PPM1G	Q13315	ATM	S325	V332A	332	Missense	distal	7	no	9.571	9.553	EPSD	COSMIC	9.540	Down-regulation
Atypical_PIKK_ATM_ATM_ST	Q14839	CHD4	Q13315	ATM	S145	E139D	139	Missense	distal	-6	no	10.016	9.801	EPSD	COSMIC	9.540	Down-regulation
Atypical_PIKK_ATM_ATM_ST	Q14839	CHD4	Q13315	ATM	S145	E138D	138	Missense	distal	-7	no	10.016	9.438	EPSD	COSMIC	9.540	Loss
Atypical_PIKK_ATM_ATM_ST	Q14839	CHD4	Q13315	ATM	S145	E147K	147	Missense	proximal	2	no	10.016	8.685	EPSD	COSMIC	9.540	Loss
Atypical_PIKK_ATM_ATM_ST	Q14839	CHD4	Q13315	ATM	S151	D157N	157	Missense	distal	6	no	11.030	11.042	EPSD	COSMIC	9.540	Up-regulation
Atypical_PIKK_ATM_ATM_ST	Q14839	CHD4	Q13315	ATM	S151	E147K	147	Missense	distal	-4	no	11.030	10.058	EPSD	COSMIC	9.540	Down-regulation
Atypical_PIKK_ATM_ATM_ST	Q14839	CHD4	Q13315	ATM	S168	V166M	166	Missense	proximal	-2	no	9.655	9.881	EPSD	COSMIC	9.540	Up-regulation
Atypical_PIKK_ATM_ATM_ST	Q14839	CHD4	Q13315	ATM	S168	D164N	164	Missense	distal	-4	no	9.655	8.731	EPSD	COSMIC	9.540	Loss
Atypical_PIKK_ATM_ATM_ST	Q14839	CHD4	Q13315	ATM	S182	T176P	176	Missense	distal	-6	no	12.750	12.760	EPSD	COSMIC	9.540	Up-regulation
Atypical_PIKK_ATM_ATM_ST	Q14839	CHD4	Q13315	ATM	S310	D316H	316	Missense	distal	6	no	11.814	11.802	EPSD	COSMIC	9.540	Down-regulation
Atypical_PIKK_ATM_ATM_ST	Q14839	CHD4	Q13315	ATM	S310	S309L	309	Missense	proximal	-1	no	11.814	11.679	EPSD	COSMIC	9.540	Down-regulation
Atypical_PIKK_ATM_ATM_ST	Q14839	CHD4	Q13315	ATM	S515	P514S	514	Missense	proximal	-1	no	11.502	11.794	EPSD	COSMIC	9.540	Up-regulation
Atypical_PIKK_ATM_ATM_ST	Q14839	CHD4	Q13315	ATM	S515	R521W	521	Missense	distal	6	no	11.502	11.470	EPSD	COSMIC	9.540	Down-regulation
Atypical_PIKK_ATM_ATM_ST	Q14839	CHD4	Q13315	ATM	S515	W508C	508	Missense	distal	-7	no	11.502	11.417	EPSD	COSMIC	9.540	Down-regulation
Atypical_PIKK_ATM_ATM_ST	Q14839	CHD4	Q13315	ATM	S515	P514L	514	Missense	proximal	-1	no	11.502	11.659	EPSD	COSMIC	9.540	Up-regulation
Atypical_PIKK_ATM_ATM_ST	Q14839	CHD4	Q13315	ATM	T529	P527L	527	Missense	proximal	-2	no	9.715	9.562	EPSD	COSMIC	9.540	Down-regulation
Atypical_PIKK_ATM_ATM_ST	Q14839	CHD4	Q13315	ATM	T529	P527S	527	Missense	proximal	-2	no	9.715	9.952	EPSD	COSMIC;GDSC	9.540	Up-regulation
Atypical_PIKK_ATM_ATM_ST	Q14839	CHD4	Q13315	ATM	T529	P534L	534	Missense	distal	5	no	9.715	9.698	EPSD	COSMIC	9.540	Down-regulation
Atypical_PIKK_ATM_ATM_ST	Q14839	CHD4	Q13315	ATM	S531	P527S	527	Missense	distal	-4	no	9.411	10.080	EPSD	COSMIC;GDSC	9.540	Gain
Atypical_PIKK_ATM_ATM_ST	Q14839	CHD4	Q13315	ATM	S531	P534L	534	Missense	distal	3	no	9.411	9.541	EPSD	COSMIC	9.540	Gain
Atypical_PIKK_ATM_ATM_ST	Q14839	CHD4	Q13315	ATM	T703	R699S	699	Missense	distal	-4	no	8.835	9.645	EPSD	COSMIC	9.540	Gain
Atypical_PIKK_ATM_ATM_ST	Q14839	CHD4	Q13315	ATM	S851	Y852H	852	Missense	proximal	1	no	10.306	1.113	EPSD	COSMIC;GDSC;CCLE	9.540	Loss
Atypical_PIKK_ATM_ATM_ST	Q14839	CHD4	Q13315	ATM	S1073	L1070F	1070	Missense	distal	-3	no	12.906	13.768	EPSD	COSMIC	9.540	Up-regulation
Atypical_PIKK_ATM_ATM_ST	Q14839	CHD4	Q13315	ATM	S1073	S1073P	1073	Missense	central	0	yes	12.906	0.000	EPSD	COSMIC	9.540	Loss
Atypical_PIKK_ATM_ATM_ST	Q14839	CHD4	Q13315	ATM	S1073	G1066V	1066	Missense	distal	-7	no	12.906	12.938	EPSD	COSMIC	9.540	Up-regulation
Atypical_PIKK_ATM_ATM_ST	Q14839	CHD4	Q13315	ATM	S1073	F1072L	1072	Missense	proximal	-1	no	12.906	13.197	EPSD	COSMIC	9.540	Up-regulation
Atypical_PIKK_ATM_ATM_ST	Q14839	CHD4	Q13315	ATM	T1207	S1211Y	1211	Missense	distal	4	no	9.350	9.654	EPSD	COSMIC	9.540	Gain
Atypical_PIKK_ATM_ATM_ST	Q14839	CHD4	Q13315	ATM	S1349	D1354N	1354	Missense	distal	5	no	16.133	16.021	PhosphoSitePlus	COSMIC	9.540	Down-regulation
Atypical_PIKK_ATM_ATM_ST	Q14839	CHD4	Q13315	ATM	S1349	Q1342H	1342	Missense	distal	-7	no	16.133	16.019	PhosphoSitePlus	COSMIC	9.540	Down-regulation
Atypical_PIKK_ATM_ATM_ST	Q14839	CHD4	Q13315	ATM	S1349	R1353Q	1353	Missense	distal	4	no	16.133	15.984	PhosphoSitePlus	COSMIC	9.540	Down-regulation
Atypical_PIKK_ATM_ATM_ST	Q14839	CHD4	Q13315	ATM	S1349	E1351Q	1351	Missense	proximal	2	no	16.133	15.320	PhosphoSitePlus	COSMIC	9.540	Down-regulation
Atypical_PIKK_ATM_ATM_ST	Q14839	CHD4	Q13315	ATM	S1388	P1384S	1384	Missense	distal	-4	no	9.098	9.768	EPSD	COSMIC	9.540	Gain
Atypical_PIKK_ATM_ATM_ST	Q14839	CHD4	Q13315	ATM	S1531	G1534V	1534	Missense	distal	3	no	13.042	13.255	EPSD	COSMIC	9.540	Up-regulation
Atypical_PIKK_ATM_ATM_ST	Q14839	CHD4	Q13315	ATM	S1531	G1534E	1534	Missense	distal	3	no	13.042	12.736	EPSD	COSMIC	9.540	Down-regulation
Atypical_PIKK_ATM_ATM_ST	Q14839	CHD4	Q13315	ATM	S1531	G1534R	1534	Missense	distal	3	no	13.042	13.097	EPSD	COSMIC;GDSC	9.540	Up-regulation
Atypical_PIKK_ATM_ATM_ST	Q14839	CHD4	Q13315	ATM	S1531	P1533A	1533	Missense	proximal	2	no	13.042	12.914	EPSD	COSMIC	9.540	Down-regulation
Atypical_PIKK_ATM_ATM_ST	Q14839	CHD4	Q13315	ATM	S1531	Q1532R	1532	Missense	proximal	1	no	13.042	6.391	EPSD	COSMIC	9.540	Loss
Atypical_PIKK_ATM_ATM_ST	Q14839	CHD4	Q13315	ATM	S1535	T1540P	1540	Missense	distal	5	no	10.548	10.746	EPSD	COSMIC	9.540	Up-regulation
Atypical_PIKK_ATM_ATM_ST	Q14839	CHD4	Q13315	ATM	S1535	P1541S	1541	Missense	distal	6	no	10.548	10.559	EPSD	COSMIC	9.540	Up-regulation
Atypical_PIKK_ATM_ATM_ST	Q14839	CHD4	Q13315	ATM	S1535	G1534V	1534	Missense	proximal	-1	no	10.548	10.316	EPSD	COSMIC	9.540	Down-regulation
Atypical_PIKK_ATM_ATM_ST	Q14839	CHD4	Q13315	ATM	S1535	G1534E	1534	Missense	proximal	-1	no	10.548	10.950	EPSD	COSMIC	9.540	Up-regulation
Atypical_PIKK_ATM_ATM_ST	Q14839	CHD4	Q13315	ATM	S1535	G1534R	1534	Missense	proximal	-1	no	10.548	10.365	EPSD	COSMIC;GDSC	9.540	Down-regulation
Atypical_PIKK_ATM_ATM_ST	Q14839	CHD4	Q13315	ATM	S1535	P1538L	1538	Missense	distal	3	no	10.548	10.678	EPSD	COSMIC	9.540	Up-regulation
Atypical_PIKK_ATM_ATM_ST	Q14839	CHD4	Q13315	ATM	S1535	P1533A	1533	Missense	proximal	-2	no	10.548	10.597	EPSD	COSMIC	9.540	Up-regulation
Atypical_PIKK_ATM_ATM_ST	Q14839	CHD4	Q13315	ATM	S1535	Q1532R	1532	Missense	distal	-3	no	10.548	11.323	EPSD	COSMIC	9.540	Up-regulation
Atypical_PIKK_ATM_ATM_ST	Q14839	CHD4	Q13315	ATM	S1544	T1545P	1545	Missense	proximal	1	no	5.093	10.100	EPSD	COSMIC	9.540	Gain
Atypical_PIKK_ATM_ATM_ST	Q14839	CHD4	Q13315	ATM	T1549	P1551L	1551	Missense	proximal	2	no	12.464	11.675	EPSD	COSMIC	9.540	Down-regulation
Atypical_PIKK_ATM_ATM_ST	Q14839	CHD4	Q13315	ATM	T1549	G1547V	1547	Missense	proximal	-2	no	12.464	12.242	EPSD	COSMIC	9.540	Down-regulation
Atypical_PIKK_ATM_ATM_ST	Q14839	CHD4	Q13315	ATM	T1549	N1552K	1552	Missense	distal	3	no	12.464	12.377	EPSD	COSMIC	9.540	Down-regulation
Atypical_PIKK_ATM_ATM_ST	Q14839	CHD4	Q13315	ATM	T1549	P1554L	1554	Missense	distal	5	no	12.464	12.447	EPSD	COSMIC	9.540	Down-regulation
Atypical_PIKK_ATM_ATM_ST	Q14839	CHD4	Q13315	ATM	T1549	P1554S	1554	Missense	distal	5	no	12.464	12.282	EPSD	COSMIC	9.540	Down-regulation
Atypical_PIKK_ATM_ATM_ST	Q14839	CHD4	Q13315	ATM	T1549	T1553P	1553	Missense	distal	4	no	12.464	12.499	EPSD	COSMIC	9.540	Up-regulation
Atypical_PIKK_ATM_ATM_ST	Q14839	CHD4	Q13315	ATM	T1549	P1546L	1546	Missense	distal	-3	no	12.464	12.476	EPSD	COSMIC	9.540	Up-regulation
Atypical_PIKK_ATM_ATM_ST	Q14839	CHD4	Q13315	ATM	T1549	P1546S	1546	Missense	distal	-3	no	12.464	12.267	EPSD	COSMIC	9.540	Down-regulation
Atypical_PIKK_ATM_ATM_ST	Q14839	CHD4	Q13315	ATM	T1549	T1545P	1545	Missense	distal	-4	no	12.464	12.178	EPSD	COSMIC	9.540	Down-regulation
Atypical_PIKK_ATM_ATM_ST	Q14839	CHD4	Q13315	ATM	T1595	E1593A	1593	Missense	proximal	-2	no	12.304	11.935	EPSD	COSMIC	9.540	Down-regulation
Atypical_PIKK_ATM_ATM_ST	Q14839	CHD4	Q13315	ATM	T1595	I1592V	1592	Missense	distal	-3	no	12.304	12.052	EPSD	COSMIC	9.540	Down-regulation
Atypical_PIKK_ATM_ATM_ST	Q14839	CHD4	Q13315	ATM	T1595	P1598R	1598	Missense	distal	3	no	12.304	12.337	EPSD	COSMIC	9.540	Up-regulation
Atypical_PIKK_ATM_ATM_ST	Q14839	CHD4	Q13315	ATM	T1595	Q1596R	1596	Missense	proximal	1	no	12.304	5.652	EPSD	COSMIC	9.540	Loss
Atypical_PIKK_ATM_ATM_ST	Q14839	CHD4	Q13315	ATM	T1595	P1600S	1600	Missense	distal	5	no	12.304	12.122	EPSD	COSMIC	9.540	Down-regulation
Atypical_PIKK_ATM_ATM_ST	Q14839	CHD4	Q13315	ATM	T1725	Y1726C	1726	Missense	proximal	1	no	10.136	3.641	EPSD	COSMIC	9.540	Loss
Atypical_PIKK_ATM_ATM_ST	Q14839	CHD4	Q13315	ATM	T1725	E1727K	1727	Missense	proximal	2	no	10.136	8.805	EPSD	COSMIC	9.540	Loss
Atypical_PIKK_ATM_ATM_ST	Q14839	CHD4	Q13315	ATM	S1808	S1812F	1812	Missense	distal	4	no	8.856	9.684	EPSD	COSMIC	9.540	Gain
Atypical_PIKK_ATM_ATM_ST	Q14839	CHD4	Q13315	ATM	T1904	R1899W	1899	Missense	distal	-5	no	9.590	9.756	EPSD	COSMIC	9.540	Up-regulation
Atypical_PIKK_ATM_ATM_ST	Q9NQS1	AVEN	Q13315	ATM	S135	S132I	132	Missense	distal	-3	no	13.656	14.326	EPSD;PhosphoSitePlus	COSMIC	9.540	Up-regulation
Atypical_PIKK_ATM_ATM_ST	Q9NQS1	AVEN	Q13315	ATM	S268	R266S	266	Missense	proximal	-2	no	12.284	12.726	EPSD	COSMIC	9.540	Up-regulation
Atypical_PIKK_ATM_ATM_ST	Q9NQS1	AVEN	Q13315	ATM	S268	S268C	268	Missense	central	0	yes	12.284	0.000	EPSD	COSMIC	9.540	Loss
Atypical_PIKK_ATM_ATM_ST	Q9NQS1	AVEN	Q13315	ATM	S268	P271L	271	Missense	distal	3	no	12.284	12.414	EPSD	COSMIC	9.540	Up-regulation
Atypical_PIKK_ATM_ATM_ST	Q9NQS1	AVEN	Q13315	ATM	S268	P274Q	274	Missense	distal	6	no	12.284	12.273	EPSD	COSMIC	9.540	Down-regulation
Atypical_PIKK_ATM_ATM_ST	Q9NQS1	AVEN	Q13315	ATM	S273	R266S	266	Missense	distal	-7	no	9.334	9.732	EPSD	COSMIC	9.540	Gain
Atypical_PIKK_ATM_ATM_ST	Q9NQS1	AVEN	Q13315	ATM	S273	P274Q	274	Missense	proximal	1	no	9.334	14.136	EPSD	COSMIC	9.540	Gain
Atypical_PIKK_ATM_ATM_ST	Q9NQS1	AVEN	Q13315	ATM	S277	G279E	279	Missense	proximal	2	no	8.546	9.915	EPSD	COSMIC	9.540	Gain
Atypical_PIKK_ATM_ATM_ST	Q9NQS1	AVEN	Q13315	ATM	S308	S313P	313	Missense	distal	5	no	14.642	14.824	PhosphoSitePlus;EPSD	COSMIC	9.540	Up-regulation
Atypical_PIKK_ATM_ATM_ST	Q9NQS1	AVEN	Q13315	ATM	S308	L311P	311	Missense	distal	3	no	14.642	14.512	PhosphoSitePlus;EPSD	COSMIC	9.540	Down-regulation
Atypical_PIKK_ATM_ATM_ST	Q9NQS1	AVEN	Q13315	ATM	S308	T307A	307	Missense	proximal	-1	no	14.642	14.471	PhosphoSitePlus;EPSD	COSMIC	9.540	Down-regulation
Atypical_PIKK_ATM_ATM_ST	P49959	MRE11	Q13315	ATM	S158	V159L	159	Missense	proximal	1	no	4.729	11.367	EPSD	COSMIC	9.540	Gain
Atypical_PIKK_ATM_ATM_ST	P49959	MRE11	Q13315	ATM	S264	Q259R	259	Missense	distal	-5	no	16.082	16.291	EPSD;PhosphoSitePlus	COSMIC	9.540	Up-regulation
Atypical_PIKK_ATM_ATM_ST	P49959	MRE11	Q13315	ATM	S264	I263V	263	Missense	proximal	-1	no	16.082	15.879	EPSD;PhosphoSitePlus	COSMIC	9.540	Down-regulation
Atypical_PIKK_ATM_ATM_ST	P49959	MRE11	Q13315	ATM	S273	L274P	274	Missense	proximal	1	no	9.322	10.877	EPSD	COSMIC	9.540	Gain
Atypical_PIKK_ATM_ATM_ST	P49959	MRE11	Q13315	ATM	T329	Q330K	330	Missense	proximal	1	no	10.280	3.432	EPSD	COSMIC;GDSC	9.540	Loss
Atypical_PIKK_ATM_ATM_ST	P49959	MRE11	Q13315	ATM	T329	P326S	326	Missense	distal	-3	no	10.280	10.084	EPSD	COSMIC	9.540	Down-regulation
Atypical_PIKK_ATM_ATM_ST	P49959	MRE11	Q13315	ATM	T329	Q333K	333	Missense	distal	4	no	10.280	10.326	EPSD	COSMIC	9.540	Up-regulation
Atypical_PIKK_ATM_ATM_ST	P49959	MRE11	Q13315	ATM	S382	R380C	380	Missense	proximal	-2	no	14.861	14.842	EPSD	COSMIC;GDSC	9.540	Down-regulation
Atypical_PIKK_ATM_ATM_ST	P49959	MRE11	Q13315	ATM	S382	R388W	388	Missense	distal	6	no	14.861	14.829	EPSD	COSMIC;GDSC	9.540	Down-regulation
Atypical_PIKK_ATM_ATM_ST	P49959	MRE11	Q13315	ATM	S382	R380H	380	Missense	proximal	-2	no	14.861	14.876	EPSD	COSMIC	9.540	Up-regulation
Atypical_PIKK_ATM_ATM_ST	P49959	MRE11	Q13315	ATM	T450	E451Q	451	Missense	proximal	1	no	5.338	11.234	EPSD	COSMIC	9.540	Gain
Atypical_PIKK_ATM_ATM_ST	P49959	MRE11	Q13315	ATM	T481	L485F	485	Missense	distal	4	no	13.419	13.905	EPSD	COSMIC	9.540	Up-regulation
Atypical_PIKK_ATM_ATM_ST	P49959	MRE11	Q13315	ATM	T481	R488H	488	Missense	distal	7	no	13.419	13.413	EPSD	COSMIC;GDSC	9.540	Down-regulation
Atypical_PIKK_ATM_ATM_ST	P49959	MRE11	Q13315	ATM	T481	Q477E	477	Missense	distal	-4	no	13.419	14.143	EPSD	COSMIC	9.540	Up-regulation
Atypical_PIKK_ATM_ATM_ST	P49959	MRE11	Q13315	ATM	T481	R483Q	483	Missense	proximal	2	no	13.419	14.115	EPSD	COSMIC	9.540	Up-regulation
Atypical_PIKK_ATM_ATM_ST	P49959	MRE11	Q13315	ATM	S531	Q532E	532	Missense	proximal	1	no	14.656	8.760	EPSD	COSMIC	9.540	Loss
Atypical_PIKK_ATM_ATM_ST	P49959	MRE11	Q13315	ATM	S531	A528T	528	Missense	distal	-3	no	14.656	15.034	EPSD	COSMIC	9.540	Up-regulation
Atypical_PIKK_ATM_ATM_ST	P49959	MRE11	Q13315	ATM	S531	S531Y	531	Missense	central	0	yes	14.656	0.000	EPSD	COSMIC	9.540	Loss
Atypical_PIKK_ATM_ATM_ST	P49959	MRE11	Q13315	ATM	S531	T524P	524	Missense	distal	-7	no	14.656	14.501	EPSD	COSMIC	9.540	Down-regulation
Atypical_PIKK_ATM_ATM_ST	P49959	MRE11	Q13315	ATM	S531	A526V	526	Missense	distal	-5	no	14.656	14.777	EPSD	COSMIC	9.540	Up-regulation
Atypical_PIKK_ATM_ATM_ST	P49959	MRE11	Q13315	ATM	S531	R525S	525	Missense	distal	-6	no	14.656	14.837	EPSD	COSMIC	9.540	Up-regulation
Atypical_PIKK_ATM_ATM_ST	P49959	MRE11	Q13315	ATM	S533	Q532E	532	Missense	proximal	-1	no	10.163	10.440	EPSD	COSMIC	9.540	Up-regulation
Atypical_PIKK_ATM_ATM_ST	P49959	MRE11	Q13315	ATM	S533	A528T	528	Missense	distal	-5	no	10.163	10.082	EPSD	COSMIC	9.540	Down-regulation
Atypical_PIKK_ATM_ATM_ST	P49959	MRE11	Q13315	ATM	S533	S531Y	531	Missense	proximal	-2	no	10.163	9.993	EPSD	COSMIC	9.540	Down-regulation
Atypical_PIKK_ATM_ATM_ST	P49959	MRE11	Q13315	ATM	S533	A526V	526	Missense	distal	-7	no	10.163	9.779	EPSD	COSMIC	9.540	Down-regulation
Atypical_PIKK_ATM_ATM_ST	P49959	MRE11	Q13315	ATM	S563	R570K	570	Missense	distal	7	no	10.164	10.152	EPSD	COSMIC	9.540	Down-regulation
Atypical_PIKK_ATM_ATM_ST	P49959	MRE11	Q13315	ATM	S563	S563L	563	Missense	central	0	yes	10.164	0.000	EPSD	COSMIC	9.540	Loss
Atypical_PIKK_ATM_ATM_ST	P49959	MRE11	Q13315	ATM	S563	S558F	558	Missense	distal	-5	no	10.164	10.488	EPSD	COSMIC	9.540	Up-regulation
Atypical_PIKK_ATM_ATM_ST	P49959	MRE11	Q13315	ATM	S563	N556S	556	Missense	distal	-7	no	10.164	10.350	EPSD	COSMIC	9.540	Up-regulation
Atypical_PIKK_ATM_ATM_ST	P49959	MRE11	Q13315	ATM	S563	S561F	561	Missense	proximal	-2	no	10.164	9.264	EPSD	COSMIC	9.540	Loss
Atypical_PIKK_ATM_ATM_ST	P49959	MRE11	Q13315	ATM	S590	S586L	586	Missense	distal	-4	no	13.983	13.044	EPSD	COSMIC	9.540	Down-regulation
Atypical_PIKK_ATM_ATM_ST	P49959	MRE11	Q13315	ATM	S590	A595S	595	Missense	distal	5	no	13.983	13.935	EPSD	COSMIC	9.540	Down-regulation
Atypical_PIKK_ATM_ATM_ST	P49959	MRE11	Q13315	ATM	S590	S584L	584	Missense	distal	-6	no	13.983	13.695	EPSD	COSMIC	9.540	Down-regulation
Atypical_PIKK_ATM_ATM_ST	P49959	MRE11	Q13315	ATM	S590	Q591E	591	Missense	proximal	1	no	13.983	8.086	EPSD	COSMIC	9.540	Loss
Atypical_PIKK_ATM_ATM_ST	P49959	MRE11	Q13315	ATM	S590	G593K	593	Missense	distal	3	no	13.983	13.966	EPSD	COSMIC	9.540	Down-regulation
Atypical_PIKK_ATM_ATM_ST	P49959	MRE11	Q13315	ATM	S590	G593R	593	Missense	distal	3	no	13.983	14.038	EPSD	COSMIC;GDSC	9.540	Up-regulation
Atypical_PIKK_ATM_ATM_ST	P49959	MRE11	Q13315	ATM	S590	G593E	593	Missense	distal	3	no	13.983	13.677	EPSD	COSMIC;GDSC	9.540	Down-regulation
Atypical_PIKK_ATM_ATM_ST	P49959	MRE11	Q13315	ATM	S590	A595V	595	Missense	distal	5	no	13.983	14.147	EPSD	COSMIC	9.540	Up-regulation
Atypical_PIKK_ATM_ATM_ST	P49959	MRE11	Q13315	ATM	S649	E652K	652	Missense	distal	3	no	9.331	9.620	EPSD	COSMIC	9.540	Gain
Atypical_PIKK_ATM_ATM_ST	P49959	MRE11	Q13315	ATM	S649	D650Y	650	Missense	proximal	1	no	9.331	9.646	EPSD	COSMIC	9.540	Gain
Atypical_PIKK_ATM_ATM_ST	P49959	MRE11	Q13315	ATM	S676	Q679K	679	Missense	distal	3	no	16.490	16.520	PhosphoSitePlus;EPSD	COSMIC	9.540	Up-regulation
Atypical_PIKK_ATM_ATM_ST	P49959	MRE11	Q13315	ATM	S676	G683R	683	Missense	distal	7	no	16.490	16.484	PhosphoSitePlus;EPSD	COSMIC	9.540	Down-regulation
Atypical_PIKK_ATM_ATM_ST	P49959	MRE11	Q13315	ATM	S676	I674N	674	Missense	proximal	-2	no	16.490	17.000	PhosphoSitePlus;EPSD	COSMIC	9.540	Up-regulation
Atypical_PIKK_ATM_ATM_ST	P49959	MRE11	Q13315	ATM	S676	Q679E	679	Missense	distal	3	no	16.490	16.231	PhosphoSitePlus;EPSD	COSMIC	9.540	Down-regulation
Atypical_PIKK_ATM_ATM_ST	P49959	MRE11	Q13315	ATM	S676	G683V	683	Missense	distal	7	no	16.490	16.497	PhosphoSitePlus;EPSD	COSMIC	9.540	Up-regulation
Atypical_PIKK_ATM_ATM_ST	P49959	MRE11	Q13315	ATM	S676	V680I	680	Missense	distal	4	no	16.490	16.847	PhosphoSitePlus;EPSD	COSMIC	9.540	Up-regulation
Atypical_PIKK_ATM_ATM_ST	P49959	MRE11	Q13315	ATM	S678	Q679K	679	Missense	proximal	1	no	15.231	8.383	EPSD;PhosphoSitePlus	COSMIC	9.540	Loss
Atypical_PIKK_ATM_ATM_ST	P49959	MRE11	Q13315	ATM	S678	G683R	683	Missense	distal	5	no	15.231	15.219	EPSD;PhosphoSitePlus	COSMIC	9.540	Down-regulation
Atypical_PIKK_ATM_ATM_ST	P49959	MRE11	Q13315	ATM	S678	I674N	674	Missense	distal	-4	no	15.231	15.014	EPSD;PhosphoSitePlus	COSMIC	9.540	Down-regulation
Atypical_PIKK_ATM_ATM_ST	P49959	MRE11	Q13315	ATM	S678	Q679E	679	Missense	proximal	1	no	15.231	9.335	EPSD;PhosphoSitePlus	COSMIC	9.540	Loss
Atypical_PIKK_ATM_ATM_ST	P49959	MRE11	Q13315	ATM	S678	G683V	683	Missense	distal	5	no	15.231	15.265	EPSD;PhosphoSitePlus	COSMIC	9.540	Up-regulation
Atypical_PIKK_ATM_ATM_ST	P49959	MRE11	Q13315	ATM	S678	V680I	680	Missense	proximal	2	no	15.231	15.439	EPSD;PhosphoSitePlus	COSMIC	9.540	Up-regulation
Atypical_PIKK_ATM_ATM_ST	P49959	MRE11	Q13315	ATM	S689	G683R	683	Missense	distal	-6	no	12.513	12.534	EPSD	COSMIC	9.540	Up-regulation
Atypical_PIKK_ATM_ATM_ST	P49959	MRE11	Q13315	ATM	S689	P696S	696	Missense	distal	7	no	12.513	12.494	EPSD	COSMIC	9.540	Down-regulation
Atypical_PIKK_ATM_ATM_ST	P49959	MRE11	Q13315	ATM	S689	G683V	683	Missense	distal	-6	no	12.513	12.458	EPSD	COSMIC	9.540	Down-regulation
Atypical_PIKK_ATM_ATM_ST	P49959	MRE11	Q13315	ATM	S689	D695Y	695	Missense	distal	6	no	12.513	12.493	EPSD	COSMIC	9.540	Down-regulation
Atypical_PIKK_ATM_ATM_ST	P49959	MRE11	Q13315	ATM	S689	D694G	694	Missense	distal	5	no	12.513	12.604	EPSD	COSMIC	9.540	Up-regulation
Atypical_PIKK_ATM_ATM_ST	P49959	MRE11	Q13315	ATM	S689	D693G	693	Missense	distal	4	no	12.513	12.434	EPSD	COSMIC	9.540	Down-regulation
Atypical_PIKK_ATM_ATM_ST	P49959	MRE11	Q13315	ATM	S689	D694Y	694	Missense	distal	5	no	12.513	12.491	EPSD	COSMIC	9.540	Down-regulation
Atypical_PIKK_ATM_ATM_ST	O00255	MEN1	Q13315	ATM	S130	W126G	126	Missense	distal	-4	no	9.414	9.912	EPSD	COSMIC	9.540	Gain
Atypical_PIKK_ATM_ATM_ST	O00255	MEN1	Q13315	ATM	S399	E392K	392	Missense	distal	-7	no	16.788	16.120	EPSD	COSMIC	9.540	Down-regulation
Atypical_PIKK_ATM_ATM_ST	O00255	MEN1	Q13315	ATM	S399	Q398E	398	Missense	proximal	-1	no	16.788	17.065	EPSD	COSMIC	9.540	Up-regulation
Atypical_PIKK_ATM_ATM_ST	O00255	MEN1	Q13315	ATM	S399	P395L	395	Missense	distal	-4	no	16.788	16.518	EPSD	COSMIC	9.540	Down-regulation
Atypical_PIKK_ATM_ATM_ST	O00255	MEN1	Q13315	ATM	T402	A408T	408	Missense	distal	6	no	13.866	13.850	EPSD	COSMIC	9.540	Down-regulation
Atypical_PIKK_ATM_ATM_ST	O00255	MEN1	Q13315	ATM	T402	Q398E	398	Missense	distal	-4	no	13.866	14.590	EPSD	COSMIC	9.540	Up-regulation
Atypical_PIKK_ATM_ATM_ST	O00255	MEN1	Q13315	ATM	T402	P395L	395	Missense	distal	-7	no	13.866	13.515	EPSD	COSMIC	9.540	Down-regulation
Atypical_PIKK_ATM_ATM_ST	O00255	MEN1	Q13315	ATM	S404	A408T	408	Missense	distal	4	no	14.283	14.718	EPSD	COSMIC	9.540	Up-regulation
Atypical_PIKK_ATM_ATM_ST	O00255	MEN1	Q13315	ATM	S404	Q398E	398	Missense	distal	-6	no	14.283	14.508	EPSD	COSMIC	9.540	Up-regulation
Atypical_PIKK_ATM_ATM_ST	O00255	MEN1	Q13315	ATM	S588	S588L	588	Missense	central	0	yes	12.678	0.000	EPSD	COSMIC	9.540	Loss
Atypical_PIKK_ATM_ATM_ST	O00255	MEN1	Q13315	ATM	S588	T585R	585	Missense	distal	-3	no	12.678	13.485	EPSD	COSMIC	9.540	Up-regulation
Atypical_PIKK_ATM_ATM_ST	Q8TAQ5	ZNF420	Q13315	ATM	S68	S73N	73	Missense	distal	5	no	13.803	13.778	PhosphoSitePlus	COSMIC	9.540	Down-regulation
Atypical_PIKK_ATM_ATM_ST	Q8TAQ5	ZNF420	Q13315	ATM	S236	K243I	243	Missense	distal	7	no	11.865	11.873	EPSD	COSMIC	9.540	Up-regulation
Atypical_PIKK_ATM_ATM_ST	Q8TAQ5	ZNF420	Q13315	ATM	S376	R374C	374	Missense	proximal	-2	no	12.568	12.549	EPSD	COSMIC	9.540	Down-regulation
Atypical_PIKK_ATM_ATM_ST	Q8TAQ5	ZNF420	Q13315	ATM	S404	R411K	411	Missense	distal	7	no	12.116	12.104	EPSD	COSMIC	9.540	Down-regulation
Atypical_PIKK_ATM_ATM_ST	Q8TAQ5	ZNF420	Q13315	ATM	S404	L406P	406	Missense	proximal	2	no	12.116	12.905	EPSD	COSMIC	9.540	Up-regulation
Atypical_PIKK_ATM_ATM_ST	Q8TAQ5	ZNF420	Q13315	ATM	S488	R495S	495	Missense	distal	7	no	12.721	12.686	EPSD	COSMIC	9.540	Down-regulation
Atypical_PIKK_ATM_ATM_ST	Q8TAQ5	ZNF420	Q13315	ATM	S488	S483Y	483	Missense	distal	-5	no	12.721	12.745	EPSD	COSMIC	9.540	Up-regulation
Atypical_PIKK_ATM_ATM_ST	Q8TAQ5	ZNF420	Q13315	ATM	S488	Q492P	492	Missense	distal	4	no	12.721	12.810	EPSD	COSMIC	9.540	Up-regulation
Atypical_PIKK_ATM_ATM_ST	Q8TAQ5	ZNF420	Q13315	ATM	S572	T575A	575	Missense	distal	3	no	12.581	12.557	EPSD	COSMIC	9.540	Down-regulation
Atypical_PIKK_ATM_ATM_ST	Q9BXS6	NUSAP1	Q13315	ATM	S57	A61V	61	Missense	distal	4	no	12.261	12.914	EPSD	COSMIC;GDSC	9.540	Up-regulation
Atypical_PIKK_ATM_ATM_ST	Q9BXS6	NUSAP1	Q13315	ATM	S101	D100G	100	Missense	proximal	-1	no	14.386	14.249	EPSD	COSMIC	9.540	Down-regulation
Atypical_PIKK_ATM_ATM_ST	Q9BXS6	NUSAP1	Q13315	ATM	S101	D100E	100	Missense	proximal	-1	no	14.386	14.650	EPSD	COSMIC	9.540	Up-regulation
Atypical_PIKK_ATM_ATM_ST	Q9BXS6	NUSAP1	Q13315	ATM	S124	A131T	131	Missense	distal	7	no	15.956	15.942	PhosphoSitePlus	COSMIC	9.540	Down-regulation
Atypical_PIKK_ATM_ATM_ST	Q9BXS6	NUSAP1	Q13315	ATM	S247	R249C	249	Missense	proximal	2	no	13.192	12.936	EPSD	COSMIC	9.540	Down-regulation
Atypical_PIKK_ATM_ATM_ST	Q9BXS6	NUSAP1	Q13315	ATM	S247	R254Q	254	Missense	distal	7	no	13.192	13.167	EPSD	COSMIC	9.540	Down-regulation
Atypical_PIKK_ATM_ATM_ST	Q9BXS6	NUSAP1	Q13315	ATM	S247	R250C	250	Missense	distal	3	no	13.192	13.428	EPSD	COSMIC	9.540	Up-regulation
Atypical_PIKK_ATM_ATM_ST	Q9BXS6	NUSAP1	Q13315	ATM	S247	Q252P	252	Missense	distal	5	no	13.192	13.320	EPSD	COSMIC;GDSC;CCLE	9.540	Up-regulation
Atypical_PIKK_ATM_ATM_ST	Q9BXS6	NUSAP1	Q13315	ATM	S251	R249C	249	Missense	proximal	-2	no	12.647	12.628	EPSD	COSMIC	9.540	Down-regulation
Atypical_PIKK_ATM_ATM_ST	Q9BXS6	NUSAP1	Q13315	ATM	S251	R254Q	254	Missense	distal	3	no	12.647	12.545	EPSD	COSMIC	9.540	Down-regulation
Atypical_PIKK_ATM_ATM_ST	Q9BXS6	NUSAP1	Q13315	ATM	S251	R250C	250	Missense	proximal	-1	no	12.647	12.822	EPSD	COSMIC	9.540	Up-regulation
Atypical_PIKK_ATM_ATM_ST	Q9BXS6	NUSAP1	Q13315	ATM	S251	Q252P	252	Missense	proximal	1	no	12.647	7.845	EPSD	COSMIC;GDSC;CCLE	9.540	Loss
Atypical_PIKK_ATM_ATM_ST	Q9BXS6	NUSAP1	Q13315	ATM	S260	R254Q	254	Missense	distal	-6	no	14.491	14.634	EPSD	COSMIC	9.540	Up-regulation
Atypical_PIKK_ATM_ATM_ST	Q9BXS6	NUSAP1	Q13315	ATM	T347	T347A	347	Missense	central	0	yes	13.787	0.000	EPSD	COSMIC	9.540	Loss
Atypical_PIKK_ATM_ATM_ST	Q9BXS6	NUSAP1	Q13315	ATM	T347	T349A	349	Missense	proximal	2	no	13.787	13.466	EPSD	COSMIC	9.540	Down-regulation
Atypical_PIKK_ATM_ATM_ST	Q9BXS6	NUSAP1	Q13315	ATM	T347	E345K	345	Missense	proximal	-2	no	13.787	13.211	EPSD	COSMIC	9.540	Down-regulation
Atypical_PIKK_ATM_ATM_ST	Q9NS91	RAD18	Q13315	ATM	T58	V65M	65	Missense	distal	7	no	13.645	13.631	EPSD	COSMIC	9.540	Down-regulation
Atypical_PIKK_ATM_ATM_ST	Q9NS91	RAD18	Q13315	ATM	S146	K151I	151	Missense	distal	5	no	11.295	11.500	EPSD	COSMIC	9.540	Up-regulation
Atypical_PIKK_ATM_ATM_ST	Q9NS91	RAD18	Q13315	ATM	S368	V372E	372	Missense	distal	4	no	11.741	11.137	EPSD	COSMIC	9.540	Down-regulation
Atypical_PIKK_ATM_ATM_ST	Q9NS91	RAD18	Q13315	ATM	S409	L413M	413	Missense	distal	4	no	10.073	9.992	EPSD	COSMIC	9.540	Down-regulation
Atypical_PIKK_ATM_ATM_ST	Q9NS91	RAD18	Q13315	ATM	S460	H461L	461	Missense	proximal	1	no	1.380	9.932	EPSD	COSMIC	9.540	Gain
Atypical_PIKK_ATM_ATM_ST	Q9NS91	RAD18	Q13315	ATM	S471	L465V	465	Missense	distal	-6	no	10.322	10.354	EPSD	COSMIC	9.540	Up-regulation
Atypical_PIKK_ATM_ATM_ST	Q9NS91	RAD18	Q13315	ATM	S471	R476S	476	Missense	distal	5	no	10.322	10.157	EPSD	COSMIC	9.540	Down-regulation
Atypical_PIKK_ATM_ATM_ST	P15927	RPA2	Q13315	ATM	T21	Y14N	14	Missense	distal	-7	no	13.325	13.434	EPSD;PhosphoSitePlus	COSMIC	9.540	Up-regulation
Atypical_PIKK_ATM_ATM_ST	P15927	RPA2	Q13315	ATM	S29	Q34K	34	Missense	distal	5	no	13.940	13.891	PhosphoSitePlus;EPSD	COSMIC	9.540	Down-regulation
Atypical_PIKK_ATM_ATM_ST	P15927	RPA2	Q13315	ATM	S33	Q34K	34	Missense	proximal	1	no	13.045	6.196	EPSD	COSMIC	9.540	Loss
Atypical_PIKK_ATM_ATM_ST	P15927	RPA2	Q13315	ATM	S33	K37N	37	Missense	distal	4	no	13.045	13.092	EPSD	COSMIC	9.540	Up-regulation
Atypical_PIKK_ATM_ATM_ST	P15927	RPA2	Q13315	ATM	S52	S56F	56	Missense	distal	4	no	14.328	15.156	EPSD	COSMIC	9.540	Up-regulation
Atypical_PIKK_ATM_ATM_ST	P15927	RPA2	Q13315	ATM	S52	S52F	52	Missense	central	0	yes	14.328	0.000	EPSD	COSMIC	9.540	Loss
Atypical_PIKK_ATM_ATM_ST	P15927	RPA2	Q13315	ATM	S52	L59F	59	Missense	distal	7	no	14.328	14.369	EPSD	COSMIC	9.540	Up-regulation
Atypical_PIKK_ATM_ATM_ST	P15927	RPA2	Q13315	ATM	S72	Q73H	73	Missense	proximal	1	no	14.027	-0.882	EPSD	COSMIC	9.540	Loss
Atypical_PIKK_ATM_ATM_ST	P15927	RPA2	Q13315	ATM	S174	P176S	176	Missense	proximal	2	no	12.596	13.051	EPSD	COSMIC	9.540	Up-regulation
Atypical_PIKK_ATM_ATM_ST	Q9UBU7	DBF4	Q13315	ATM	S84	D82N	82	Missense	proximal	-2	no	10.785	10.904	EPSD	COSMIC	9.540	Up-regulation
Atypical_PIKK_ATM_ATM_ST	Q9UBU7	DBF4	Q13315	ATM	S130	S127L	127	Missense	distal	-3	no	9.840	10.050	EPSD	COSMIC	9.540	Up-regulation
Atypical_PIKK_ATM_ATM_ST	Q9UBU7	DBF4	Q13315	ATM	S130	P131S	131	Missense	proximal	1	no	9.840	2.865	EPSD	COSMIC	9.540	Loss
Atypical_PIKK_ATM_ATM_ST	Q9UBU7	DBF4	Q13315	ATM	S130	P131L	131	Missense	proximal	1	no	9.840	8.286	EPSD	COSMIC	9.540	Loss
Atypical_PIKK_ATM_ATM_ST	Q9UBU7	DBF4	Q13315	ATM	S381	H379N	379	Missense	proximal	-2	no	14.687	14.935	EPSD	COSMIC	9.540	Up-regulation
Atypical_PIKK_ATM_ATM_ST	Q9UBU7	DBF4	Q13315	ATM	T449	L453E	453	Missense	distal	4	no	13.057	12.417	EPSD;PhosphoSitePlus	COSMIC	9.540	Down-regulation
Atypical_PIKK_ATM_ATM_ST	Q9UBU7	DBF4	Q13315	ATM	S502	P504S	504	Missense	proximal	2	no	15.223	15.677	PhosphoSitePlus;EPSD	COSMIC	9.540	Up-regulation
Atypical_PIKK_ATM_ATM_ST	Q9UBU7	DBF4	Q13315	ATM	S539	S538R	538	Missense	proximal	-1	no	14.650	14.276	EPSD;PhosphoSitePlus	COSMIC	9.540	Down-regulation
Atypical_PIKK_ATM_ATM_ST	Q9UBU7	DBF4	Q13315	ATM	S613	D620N	620	Missense	distal	7	no	10.194	10.201	EPSD	COSMIC	9.540	Up-regulation
Atypical_PIKK_ATM_ATM_ST	Q9UBU7	DBF4	Q13315	ATM	S613	S612T	612	Missense	proximal	-1	no	10.194	10.204	EPSD	COSMIC	9.540	Up-regulation
Atypical_PIKK_ATM_ATM_ST	Q14247	CTTN	Q13315	ATM	S47	S47F	47	Missense	central	0	yes	9.736	0.000	EPSD	COSMIC	9.540	Loss
Atypical_PIKK_ATM_ATM_ST	Q14247	CTTN	Q13315	ATM	S150	G143W	143	Missense	distal	-7	no	13.584	13.509	EPSD	COSMIC	9.540	Down-regulation
Atypical_PIKK_ATM_ATM_ST	Q14247	CTTN	Q13315	ATM	S150	Y154C	154	Missense	distal	4	no	13.584	13.790	EPSD	COSMIC;CCLE	9.540	Up-regulation
Atypical_PIKK_ATM_ATM_ST	Q14247	CTTN	Q13315	ATM	S187	D190N	190	Missense	distal	3	no	13.838	13.855	EPSD	COSMIC	9.540	Up-regulation
Atypical_PIKK_ATM_ATM_ST	Q14247	CTTN	Q13315	ATM	S224	S224F	224	Missense	central	0	yes	14.223	0.000	EPSD	COSMIC	9.540	Loss
Atypical_PIKK_ATM_ATM_ST	Q14247	CTTN	Q13315	ATM	S261	S261F	261	Missense	central	0	yes	15.291	0.000	EPSD	COSMIC	9.540	Loss
Atypical_PIKK_ATM_ATM_ST	Q14247	CTTN	Q13315	ATM	T328	V330E	330	Missense	proximal	2	no	8.859	10.262	EPSD	COSMIC	9.540	Gain
Atypical_PIKK_ATM_ATM_ST	Q14247	CTTN	Q13315	ATM	T399	Q394K	394	Missense	distal	-5	no	14.506	14.556	EPSD	COSMIC	9.540	Up-regulation
Atypical_PIKK_ATM_ATM_ST	Q14247	CTTN	Q13315	ATM	T399	R396T	396	Missense	distal	-3	no	14.506	13.698	EPSD	COSMIC	9.540	Down-regulation
Atypical_PIKK_ATM_ATM_ST	Q14247	CTTN	Q13315	ATM	T401	Q394K	394	Missense	distal	-7	no	9.952	9.838	EPSD	COSMIC	9.540	Down-regulation
Atypical_PIKK_ATM_ATM_ST	Q14247	CTTN	Q13315	ATM	T401	R396T	396	Missense	distal	-5	no	9.952	9.787	EPSD	COSMIC	9.540	Down-regulation
Atypical_PIKK_ATM_ATM_ST	Q9Y6D9	MAD1L1	Q13315	ATM	S22	F20L	20	Missense	proximal	-2	no	12.975	13.486	EPSD	COSMIC	9.540	Up-regulation
Atypical_PIKK_ATM_ATM_ST	Q9Y6D9	MAD1L1	Q13315	ATM	S214	A213T	213	Missense	proximal	-1	no	15.744	15.915	PhosphoSitePlus	COSMIC	9.540	Up-regulation
Atypical_PIKK_ATM_ATM_ST	Q9Y6D9	MAD1L1	Q13315	ATM	S214	D220V	220	Missense	distal	6	no	15.744	15.742	PhosphoSitePlus	COSMIC	9.540	Down-regulation
Atypical_PIKK_ATM_ATM_ST	Q9Y6D9	MAD1L1	Q13315	ATM	S214	H221N	221	Missense	distal	7	no	15.744	15.730	PhosphoSitePlus	COSMIC	9.540	Down-regulation
Atypical_PIKK_ATM_ATM_ST	Q9Y6D9	MAD1L1	Q13315	ATM	S358	R360Q	360	Missense	proximal	2	no	9.265	9.960	EPSD	COSMIC	9.540	Gain
Atypical_PIKK_ATM_ATM_ST	Q9Y6D9	MAD1L1	Q13315	ATM	T423	P424Q	424	Missense	proximal	1	no	8.126	12.928	EPSD	COSMIC	9.540	Gain
Atypical_PIKK_ATM_ATM_ST	Q9Y6D9	MAD1L1	Q13315	ATM	S428	T432M	432	Missense	distal	4	no	10.144	10.317	EPSD	COSMIC	9.540	Up-regulation
Atypical_PIKK_ATM_ATM_ST	Q9Y6D9	MAD1L1	Q13315	ATM	S428	R433W	433	Missense	distal	5	no	10.144	10.168	EPSD	COSMIC	9.540	Up-regulation
Atypical_PIKK_ATM_ATM_ST	Q9Y6D9	MAD1L1	Q13315	ATM	S428	E421D	421	Missense	distal	-7	no	10.144	9.566	EPSD	COSMIC	9.540	Down-regulation
Atypical_PIKK_ATM_ATM_ST	Q9Y6D9	MAD1L1	Q13315	ATM	S428	P424Q	424	Missense	distal	-4	no	10.144	10.368	EPSD	COSMIC	9.540	Up-regulation
Atypical_PIKK_ATM_ATM_ST	Q9Y6D9	MAD1L1	Q13315	ATM	S428	P424T	424	Missense	distal	-4	no	10.144	10.430	EPSD	COSMIC	9.540	Up-regulation
Atypical_PIKK_ATM_ATM_ST	Q9Y6D9	MAD1L1	Q13315	ATM	S457	G464E	464	Missense	distal	7	no	14.216	14.171	EPSD	COSMIC	9.540	Down-regulation
Atypical_PIKK_ATM_ATM_ST	Q9Y6D9	MAD1L1	Q13315	ATM	S457	A450T	450	Missense	distal	-7	no	14.216	14.232	EPSD	COSMIC	9.540	Up-regulation
Atypical_PIKK_ATM_ATM_ST	Q9Y6D9	MAD1L1	Q13315	ATM	S457	L463M	463	Missense	distal	6	no	14.216	14.244	EPSD	COSMIC	9.540	Up-regulation
Atypical_PIKK_ATM_ATM_ST	Q9Y6D9	MAD1L1	Q13315	ATM	S482	S485C	485	Missense	distal	3	no	14.332	14.753	EPSD	COSMIC	9.540	Up-regulation
Atypical_PIKK_ATM_ATM_ST	Q9Y6D9	MAD1L1	Q13315	ATM	S494	L501P	501	Missense	distal	7	no	10.044	10.043	EPSD	COSMIC	9.540	Down-regulation
Atypical_PIKK_ATM_ATM_ST	Q9Y6D9	MAD1L1	Q13315	ATM	S494	F493L	493	Missense	proximal	-1	no	10.044	10.335	EPSD	COSMIC	9.540	Up-regulation
Atypical_PIKK_ATM_ATM_ST	Q9Y6D9	MAD1L1	Q13315	ATM	S494	E496D	496	Missense	proximal	2	no	10.044	9.913	EPSD	COSMIC;GDSC;CCLE	9.540	Down-regulation
Atypical_PIKK_ATM_ATM_ST	Q9Y6D9	MAD1L1	Q13315	ATM	S494	A498S	498	Missense	distal	4	no	10.044	10.391	EPSD	COSMIC	9.540	Up-regulation
Atypical_PIKK_ATM_ATM_ST	Q9Y6D9	MAD1L1	Q13315	ATM	S513	R514Q	514	Missense	proximal	1	no	8.582	15.233	EPSD	COSMIC	9.540	Gain
Atypical_PIKK_ATM_ATM_ST	Q9Y6D9	MAD1L1	Q13315	ATM	S562	R558H	558	Missense	distal	-4	no	14.822	14.952	EPSD	COSMIC	9.540	Up-regulation
Atypical_PIKK_ATM_ATM_ST	Q9Y6D9	MAD1L1	Q13315	ATM	S562	E559K	559	Missense	distal	-3	no	14.822	14.889	EPSD	COSMIC	9.540	Up-regulation
Atypical_PIKK_ATM_ATM_ST	Q9Y6D9	MAD1L1	Q13315	ATM	S610	R617Q	617	Missense	distal	7	no	9.855	9.830	EPSD	COSMIC;GDSC;CCLE	9.540	Down-regulation
Atypical_PIKK_ATM_ATM_ST	Q9Y6D9	MAD1L1	Q13315	ATM	S610	Q616L	616	Missense	distal	6	no	9.855	9.820	EPSD	COSMIC	9.540	Down-regulation
Atypical_PIKK_ATM_ATM_ST	Q9Y6D9	MAD1L1	Q13315	ATM	S610	R617W	617	Missense	distal	7	no	9.855	9.881	EPSD	COSMIC	9.540	Up-regulation
Atypical_PIKK_ATM_ATM_ST	O96028	NSD2	Q13315	ATM	S56	L53F	53	Missense	distal	-3	no	9.111	9.974	EPSD	COSMIC	9.540	Gain
Atypical_PIKK_ATM_ATM_ST	O96028	NSD2	Q13315	ATM	S102	G109W	109	Missense	distal	7	no	15.019	15.039	PhosphoSitePlus	COSMIC	9.540	Up-regulation
Atypical_PIKK_ATM_ATM_ST	O96028	NSD2	Q13315	ATM	S102	E104K	104	Missense	proximal	2	no	15.019	13.689	PhosphoSitePlus	COSMIC	9.540	Down-regulation
Atypical_PIKK_ATM_ATM_ST	O96028	NSD2	Q13315	ATM	S102	R99C	99	Missense	distal	-3	no	15.019	14.447	PhosphoSitePlus	COSMIC	9.540	Down-regulation
Atypical_PIKK_ATM_ATM_ST	O96028	NSD2	Q13315	ATM	S102	D95N	95	Missense	distal	-7	no	15.019	15.055	PhosphoSitePlus	COSMIC	9.540	Up-regulation
Atypical_PIKK_ATM_ATM_ST	O96028	NSD2	Q13315	ATM	S121	K125N	125	Missense	distal	4	no	11.038	11.086	EPSD	COSMIC	9.540	Up-regulation
Atypical_PIKK_ATM_ATM_ST	O96028	NSD2	Q13315	ATM	S154	E155Q	155	Missense	proximal	1	no	10.125	16.021	EPSD	COSMIC	9.540	Up-regulation
Atypical_PIKK_ATM_ATM_ST	O96028	NSD2	Q13315	ATM	S154	N157Y	157	Missense	distal	3	no	10.125	10.166	EPSD	COSMIC	9.540	Up-regulation
Atypical_PIKK_ATM_ATM_ST	O96028	NSD2	Q13315	ATM	S154	K160E	160	Missense	distal	6	no	10.125	10.170	EPSD	COSMIC	9.540	Up-regulation
Atypical_PIKK_ATM_ATM_ST	O96028	NSD2	Q13315	ATM	S518	D517N	517	Missense	proximal	-1	no	9.986	9.985	EPSD	COSMIC	9.540	Down-regulation
Atypical_PIKK_ATM_ATM_ST	O96028	NSD2	Q13315	ATM	S518	G523W	523	Missense	distal	5	no	9.986	9.997	EPSD	COSMIC	9.540	Up-regulation
Atypical_PIKK_ATM_ATM_ST	O96028	NSD2	Q13315	ATM	S518	G523E	523	Missense	distal	5	no	9.986	9.637	EPSD	COSMIC	9.540	Down-regulation
Atypical_PIKK_ATM_ATM_ST	O96028	NSD2	Q13315	ATM	S518	K525R	525	Missense	distal	7	no	9.986	9.998	EPSD	COSMIC	9.540	Up-regulation
Atypical_PIKK_ATM_ATM_ST	O96028	NSD2	Q13315	ATM	S518	V512A	512	Missense	distal	-6	no	9.986	10.222	EPSD	COSMIC	9.540	Up-regulation
Atypical_PIKK_ATM_ATM_ST	O96028	NSD2	Q13315	ATM	S571	K573E	573	Missense	proximal	2	no	8.496	9.827	EPSD	COSMIC	9.540	Gain
Atypical_PIKK_ATM_ATM_ST	O96028	NSD2	Q13315	ATM	S583	Q584K	584	Missense	proximal	1	no	14.280	7.431	EPSD	COSMIC	9.540	Loss
Atypical_PIKK_ATM_ATM_ST	O96028	NSD2	Q13315	ATM	S583	A586P	586	Missense	distal	3	no	14.280	14.376	EPSD	COSMIC	9.540	Up-regulation
Atypical_PIKK_ATM_ATM_ST	O96028	NSD2	Q13315	ATM	S583	S580P	580	Missense	distal	-3	no	14.280	14.476	EPSD	COSMIC	9.540	Up-regulation
Atypical_PIKK_ATM_ATM_ST	O96028	NSD2	Q13315	ATM	S583	S580L	580	Missense	distal	-3	no	14.280	14.489	EPSD	COSMIC	9.540	Up-regulation
Atypical_PIKK_ATM_ATM_ST	O96028	NSD2	Q13315	ATM	S583	E576K	576	Missense	distal	-7	no	14.280	13.612	EPSD	COSMIC	9.540	Down-regulation
Atypical_PIKK_ATM_ATM_ST	O96028	NSD2	Q13315	ATM	S622	E627D	627	Missense	distal	5	no	9.997	10.254	EPSD	COSMIC	9.540	Up-regulation
Atypical_PIKK_ATM_ATM_ST	O96028	NSD2	Q13315	ATM	S754	R755Q	755	Missense	proximal	1	no	7.616	14.267	EPSD	COSMIC	9.540	Gain
Atypical_PIKK_ATM_ATM_ST	O96028	NSD2	Q13315	ATM	S1030	E1031Q	1031	Missense	proximal	1	no	11.120	17.017	EPSD	COSMIC	9.540	Up-regulation
Atypical_PIKK_ATM_ATM_ST	O96028	NSD2	Q13315	ATM	S1030	L1037M	1037	Missense	distal	7	no	11.120	11.134	EPSD	COSMIC	9.540	Up-regulation
Atypical_PIKK_ATM_ATM_ST	O96028	NSD2	Q13315	ATM	S1238	C1245F	1245	Missense	distal	7	no	9.583	9.591	EPSD	COSMIC	9.540	Up-regulation
Atypical_PIKK_ATM_ATM_ST	O96028	NSD2	Q13315	ATM	S1238	R1236K	1236	Missense	proximal	-2	no	9.583	9.631	EPSD	COSMIC	9.540	Up-regulation
Atypical_PIKK_ATM_ATM_ST	O96028	NSD2	Q13315	ATM	S1238	G1234E	1234	Missense	distal	-4	no	9.583	10.650	EPSD	COSMIC	9.540	Up-regulation
Atypical_PIKK_ATM_ATM_ST	O96028	NSD2	Q13315	ATM	S1238	R1244S	1244	Missense	distal	6	no	9.583	9.601	EPSD	COSMIC	9.540	Up-regulation
Atypical_PIKK_ATM_ATM_ST	O96028	NSD2	Q13315	ATM	S1238	R1244C	1244	Missense	distal	6	no	9.583	9.529	EPSD	COSMIC	9.540	Loss
Atypical_PIKK_ATM_ATM_ST	P15374	UCHL3	Q13315	ATM	S130	R134Q	134	Missense	distal	4	no	10.957	10.808	EPSD	COSMIC	9.540	Down-regulation
Atypical_PIKK_ATM_ATM_ST	Q70CQ2	USP34	Q13315	ATM	S143	L148S	148	Missense	distal	5	no	9.892	9.727	EPSD	COSMIC	9.540	Down-regulation
Atypical_PIKK_ATM_ATM_ST	Q70CQ2	USP34	Q13315	ATM	T188	P181S	181	Missense	distal	-7	no	13.341	13.577	EPSD	COSMIC	9.540	Up-regulation
Atypical_PIKK_ATM_ATM_ST	Q70CQ2	USP34	Q13315	ATM	T188	P181T	181	Missense	distal	-7	no	13.341	13.496	EPSD	COSMIC	9.540	Up-regulation
Atypical_PIKK_ATM_ATM_ST	Q70CQ2	USP34	Q13315	ATM	S324	A318P	318	Missense	distal	-6	no	10.765	10.726	EPSD	COSMIC	9.540	Down-regulation
Atypical_PIKK_ATM_ATM_ST	Q70CQ2	USP34	Q13315	ATM	S324	T326S	326	Missense	proximal	2	no	10.765	11.027	EPSD	COSMIC	9.540	Up-regulation
Atypical_PIKK_ATM_ATM_ST	Q70CQ2	USP34	Q13315	ATM	S649	R643W	643	Missense	distal	-6	no	14.044	13.876	EPSD	COSMIC	9.540	Down-regulation
Atypical_PIKK_ATM_ATM_ST	Q70CQ2	USP34	Q13315	ATM	S649	E648G	648	Missense	proximal	-1	no	14.044	13.642	EPSD	COSMIC;GDSC	9.540	Down-regulation
Atypical_PIKK_ATM_ATM_ST	Q70CQ2	USP34	Q13315	ATM	S649	C654S	654	Missense	distal	5	no	14.044	13.818	EPSD	COSMIC	9.540	Down-regulation
Atypical_PIKK_ATM_ATM_ST	Q70CQ2	USP34	Q13315	ATM	S649	L647Y	647	Missense	proximal	-2	no	14.044	14.264	EPSD	COSMIC	9.540	Up-regulation
Atypical_PIKK_ATM_ATM_ST	Q70CQ2	USP34	Q13315	ATM	S658	C654S	654	Missense	distal	-4	no	12.913	14.486	EPSD	COSMIC	9.540	Up-regulation
Atypical_PIKK_ATM_ATM_ST	Q70CQ2	USP34	Q13315	ATM	S658	M661I	661	Missense	distal	3	no	12.913	13.158	EPSD	COSMIC	9.540	Up-regulation
Atypical_PIKK_ATM_ATM_ST	Q70CQ2	USP34	Q13315	ATM	S718	Q719E	719	Missense	proximal	1	no	15.869	9.972	EPSD;PhosphoSitePlus	COSMIC	9.540	Down-regulation
Atypical_PIKK_ATM_ATM_ST	Q70CQ2	USP34	Q13315	ATM	S718	I714T	714	Missense	distal	-4	no	15.869	16.197	EPSD;PhosphoSitePlus	COSMIC;GDSC	9.540	Up-regulation
Atypical_PIKK_ATM_ATM_ST	Q70CQ2	USP34	Q13315	ATM	S718	A711V	711	Missense	distal	-7	no	15.869	15.485	EPSD;PhosphoSitePlus	COSMIC	9.540	Down-regulation
Atypical_PIKK_ATM_ATM_ST	Q70CQ2	USP34	Q13315	ATM	S718	A711T	711	Missense	distal	-7	no	15.869	15.885	EPSD;PhosphoSitePlus	COSMIC	9.540	Up-regulation
Atypical_PIKK_ATM_ATM_ST	Q70CQ2	USP34	Q13315	ATM	S718	A711D	711	Missense	distal	-7	no	15.869	15.743	EPSD;PhosphoSitePlus	COSMIC	9.540	Down-regulation
Atypical_PIKK_ATM_ATM_ST	Q70CQ2	USP34	Q13315	ATM	S920	I919N	919	Missense	proximal	-1	no	11.689	11.854	EPSD	COSMIC	9.540	Up-regulation
Atypical_PIKK_ATM_ATM_ST	Q70CQ2	USP34	Q13315	ATM	S920	L924F	924	Missense	distal	4	no	11.689	12.175	EPSD	COSMIC	9.540	Up-regulation
Atypical_PIKK_ATM_ATM_ST	Q70CQ2	USP34	Q13315	ATM	S1208	L1209P	1209	Missense	proximal	1	no	9.373	10.928	EPSD	COSMIC	9.540	Gain
Atypical_PIKK_ATM_ATM_ST	Q70CQ2	USP34	Q13315	ATM	S1375	R1379G	1379	Missense	distal	4	no	10.765	10.712	EPSD	COSMIC	9.540	Down-regulation
Atypical_PIKK_ATM_ATM_ST	Q70CQ2	USP34	Q13315	ATM	S1375	D1373G	1373	Missense	proximal	-2	no	10.765	10.621	EPSD	COSMIC	9.540	Down-regulation
Atypical_PIKK_ATM_ATM_ST	Q70CQ2	USP34	Q13315	ATM	S1473	D1475N	1475	Missense	proximal	2	no	12.350	11.329	EPSD	COSMIC	9.540	Down-regulation
Atypical_PIKK_ATM_ATM_ST	Q70CQ2	USP34	Q13315	ATM	S1751	T1753A	1753	Missense	proximal	2	no	15.444	15.123	PhosphoSitePlus;EPSD	COSMIC;GDSC	9.540	Down-regulation
Atypical_PIKK_ATM_ATM_ST	Q70CQ2	USP34	Q13315	ATM	S1751	S1751G	1751	Missense	central	0	yes	15.444	0.000	PhosphoSitePlus;EPSD	COSMIC	9.540	Loss
Atypical_PIKK_ATM_ATM_ST	Q70CQ2	USP34	Q13315	ATM	S2339	N2337S	2337	Missense	proximal	-2	no	14.238	14.418	EPSD	COSMIC	9.540	Up-regulation
Atypical_PIKK_ATM_ATM_ST	Q70CQ2	USP34	Q13315	ATM	S2706	D2713G	2713	Missense	distal	7	no	9.520	9.553	EPSD	COSMIC;GDSC;CCLE	9.540	Gain
Atypical_PIKK_ATM_ATM_ST	Q70CQ2	USP34	Q13315	ATM	T3195	S3200L	3200	Missense	distal	5	no	13.155	13.320	EPSD	COSMIC	9.540	Up-regulation
Atypical_PIKK_ATM_ATM_ST	Q70CQ2	USP34	Q13315	ATM	T3350	R3354K	3354	Missense	distal	4	no	10.611	10.509	EPSD	COSMIC	9.540	Down-regulation
Atypical_PIKK_ATM_ATM_ST	Q70CQ2	USP34	Q13315	ATM	T3350	R3356S	3356	Missense	distal	6	no	10.611	10.629	EPSD	COSMIC	9.540	Up-regulation
Atypical_PIKK_ATM_ATM_ST	Q70CQ2	USP34	Q13315	ATM	T3350	R3356P	3356	Missense	distal	6	no	10.611	10.618	EPSD	COSMIC	9.540	Up-regulation
Atypical_PIKK_ATM_ATM_ST	Q13769	THOC5	Q13315	ATM	S307	P303F	303	Missense	distal	-4	no	13.722	12.993	EPSD;PhosphoSitePlus	COSMIC	9.540	Down-regulation
Atypical_PIKK_ATM_ATM_ST	Q13769	THOC5	Q13315	ATM	S307	E305D	305	Missense	proximal	-2	no	13.722	13.243	EPSD;PhosphoSitePlus	COSMIC	9.540	Down-regulation
Atypical_PIKK_ATM_ATM_ST	Q13769	THOC5	Q13315	ATM	S307	D306Y	306	Missense	proximal	-1	no	13.722	13.728	EPSD;PhosphoSitePlus	COSMIC	9.540	Up-regulation
Atypical_PIKK_ATM_ATM_ST	Q13769	THOC5	Q13315	ATM	T536	E532A	532	Missense	distal	-4	no	10.670	9.882	EPSD	COSMIC	9.540	Down-regulation
Atypical_PIKK_ATM_ATM_ST	Q13769	THOC5	Q13315	ATM	T536	Y530C	530	Missense	distal	-6	no	10.670	10.540	EPSD	COSMIC	9.540	Down-regulation
Atypical_PIKK_ATM_ATM_ST	Q9UQE7	SMC3	Q13315	ATM	S177	R171Q	171	Missense	distal	-6	no	10.314	10.458	EPSD	COSMIC	9.540	Up-regulation
Atypical_PIKK_ATM_ATM_ST	Q9UQE7	SMC3	Q13315	ATM	S177	I176L	176	Missense	proximal	-1	no	10.314	10.400	EPSD	COSMIC	9.540	Up-regulation
Atypical_PIKK_ATM_ATM_ST	Q9UQE7	SMC3	Q13315	ATM	S177	E181Q	181	Missense	distal	4	no	10.314	10.646	EPSD	COSMIC	9.540	Up-regulation
Atypical_PIKK_ATM_ATM_ST	Q9UQE7	SMC3	Q13315	ATM	T347	E343K	343	Missense	distal	-4	no	9.679	8.707	EPSD	COSMIC	9.540	Loss
Atypical_PIKK_ATM_ATM_ST	Q9UQE7	SMC3	Q13315	ATM	S383	E390Q	390	Missense	distal	7	no	12.017	12.031	EPSD	COSMIC	9.540	Up-regulation
Atypical_PIKK_ATM_ATM_ST	Q9UQE7	SMC3	Q13315	ATM	S387	E390Q	390	Missense	distal	3	no	9.324	9.583	EPSD	COSMIC	9.540	Gain
Atypical_PIKK_ATM_ATM_ST	Q9UQE7	SMC3	Q13315	ATM	T640	C633Y	633	Missense	distal	-7	no	10.150	10.528	EPSD	COSMIC	9.540	Up-regulation
Atypical_PIKK_ATM_ATM_ST	Q9UQE7	SMC3	Q13315	ATM	T640	R644S	644	Missense	distal	4	no	10.150	9.968	EPSD	COSMIC	9.540	Down-regulation
Atypical_PIKK_ATM_ATM_ST	Q9UQE7	SMC3	Q13315	ATM	T640	F646Y	646	Missense	distal	6	no	10.150	10.184	EPSD	COSMIC	9.540	Up-regulation
Atypical_PIKK_ATM_ATM_ST	Q9UQE7	SMC3	Q13315	ATM	T640	R634H	634	Missense	distal	-6	no	10.150	10.151	EPSD	COSMIC;GDSC;CCLE	9.540	Up-regulation
Atypical_PIKK_ATM_ATM_ST	Q9UQE7	SMC3	Q13315	ATM	T665	G667D	667	Missense	proximal	2	no	8.424	9.663	EPSD	COSMIC	9.540	Gain
Atypical_PIKK_ATM_ATM_ST	Q9UQE7	SMC3	Q13315	ATM	S731	S731A	731	Missense	central	0	yes	10.330	0.000	EPSD	COSMIC	9.540	Loss
Atypical_PIKK_ATM_ATM_ST	Q9UQE7	SMC3	Q13315	ATM	S737	M739T	739	Missense	proximal	2	no	9.270	10.065	EPSD	COSMIC	9.540	Gain
Atypical_PIKK_ATM_ATM_ST	Q9UQE7	SMC3	Q13315	ATM	S787	E780K	780	Missense	distal	-7	no	14.362	13.694	EPSD	COSMIC	9.540	Down-regulation
Atypical_PIKK_ATM_ATM_ST	Q9UQE7	SMC3	Q13315	ATM	S1074	S1077R	1077	Missense	distal	3	no	9.487	9.673	EPSD	COSMIC	9.540	Gain
Atypical_PIKK_ATM_ATM_ST	Q9UQE7	SMC3	Q13315	ATM	S1083	S1081Y	1081	Missense	proximal	-2	no	16.913	16.743	PhosphoSitePlus	COSMIC	9.540	Down-regulation
Atypical_PIKK_ATM_ATM_ST	Q9UQE7	SMC3	Q13315	ATM	S1083	G1080D	1080	Missense	distal	-3	no	16.913	16.881	PhosphoSitePlus	COSMIC	9.540	Down-regulation
Atypical_PIKK_ATM_ATM_ST	Q9UQE7	SMC3	Q13315	ATM	S1083	S1077R	1077	Missense	distal	-6	no	16.913	16.733	PhosphoSitePlus	COSMIC	9.540	Down-regulation
Atypical_PIKK_ATM_ATM_ST	Q9UQE7	SMC3	Q13315	ATM	S1083	R1079G	1079	Missense	distal	-4	no	16.913	16.935	PhosphoSitePlus	COSMIC	9.540	Up-regulation
Atypical_PIKK_ATM_ATM_ST	Q13315	ATM	Q13315	ATM	T86	A88V	88	Missense	proximal	2	no	13.802	13.493	EPSD	COSMIC	9.540	Down-regulation
Atypical_PIKK_ATM_ATM_ST	Q13315	ATM	Q13315	ATM	T86	S83L	83	Missense	distal	-3	no	13.802	14.011	EPSD	COSMIC	9.540	Up-regulation
Atypical_PIKK_ATM_ATM_ST	Q13315	ATM	Q13315	ATM	T86	A84V	84	Missense	proximal	-2	no	13.802	13.325	EPSD	COSMIC	9.540	Down-regulation
Atypical_PIKK_ATM_ATM_ST	Q13315	ATM	Q13315	ATM	S89	M94I	94	Missense	distal	5	no	9.520	9.545	EPSD	COSMIC	9.540	Gain
Atypical_PIKK_ATM_ATM_ST	Q13315	ATM	Q13315	ATM	S89	M94V	94	Missense	distal	5	no	9.520	9.547	EPSD	COSMIC	9.540	Gain
Atypical_PIKK_ATM_ATM_ST	Q13315	ATM	Q13315	ATM	S89	A84V	84	Missense	distal	-5	no	9.520	9.641	EPSD	COSMIC	9.540	Gain
Atypical_PIKK_ATM_ATM_ST	Q13315	ATM	Q13315	ATM	S200	D203N	203	Missense	distal	3	no	14.132	14.149	EPSD	COSMIC	9.540	Up-regulation
Atypical_PIKK_ATM_ATM_ST	Q13315	ATM	Q13315	ATM	S200	S207F	207	Missense	distal	7	no	14.132	14.192	EPSD	COSMIC	9.540	Up-regulation
Atypical_PIKK_ATM_ATM_ST	Q13315	ATM	Q13315	ATM	T297	P292R	292	Missense	distal	-5	no	14.760	14.832	EPSD	COSMIC	9.540	Up-regulation
Atypical_PIKK_ATM_ATM_ST	Q13315	ATM	Q13315	ATM	T297	G294E	294	Missense	distal	-3	no	14.760	14.322	EPSD	COSMIC	9.540	Down-regulation
Atypical_PIKK_ATM_ATM_ST	Q13315	ATM	Q13315	ATM	T297	H290L	290	Missense	distal	-7	no	14.760	14.485	EPSD	COSMIC	9.540	Down-regulation
Atypical_PIKK_ATM_ATM_ST	Q13315	ATM	Q13315	ATM	T297	H291R	291	Missense	distal	-6	no	14.760	14.759	EPSD	COSMIC;GDSC;CCLE	9.540	Down-regulation
Atypical_PIKK_ATM_ATM_ST	Q13315	ATM	Q13315	ATM	T297	G301C	301	Missense	distal	4	no	14.760	15.140	EPSD	COSMIC	9.540	Up-regulation
Atypical_PIKK_ATM_ATM_ST	Q13315	ATM	Q13315	ATM	T297	E304G	304	Missense	distal	7	no	14.760	14.805	EPSD	COSMIC	9.540	Up-regulation
Atypical_PIKK_ATM_ATM_ST	Q13315	ATM	Q13315	ATM	S367	T372A	372	Missense	distal	5	no	15.079	15.144	PhosphoSitePlus;EPSD	COSMIC	9.540	Up-regulation
Atypical_PIKK_ATM_ATM_ST	Q13315	ATM	Q13315	ATM	S369	T372A	372	Missense	distal	3	no	10.128	10.104	EPSD	COSMIC	9.540	Down-regulation
Atypical_PIKK_ATM_ATM_ST	Q13315	ATM	Q13315	ATM	T373	Y380N	380	Missense	distal	7	no	13.680	13.661	EPSD	COSMIC	9.540	Down-regulation
Atypical_PIKK_ATM_ATM_ST	Q13315	ATM	Q13315	ATM	T373	T372A	372	Missense	proximal	-1	no	13.680	13.509	EPSD	COSMIC	9.540	Down-regulation
Atypical_PIKK_ATM_ATM_ST	Q13315	ATM	Q13315	ATM	S378	Y380N	380	Missense	proximal	2	no	9.349	9.569	EPSD	COSMIC	9.540	Gain
Atypical_PIKK_ATM_ATM_ST	Q13315	ATM	Q13315	ATM	S440	P434L	434	Missense	distal	-6	no	13.724	13.494	EPSD;PhosphoSitePlus	COSMIC	9.540	Down-regulation
Atypical_PIKK_ATM_ATM_ST	Q13315	ATM	Q13315	ATM	S646	E647Q	647	Missense	proximal	1	no	10.013	15.909	EPSD	COSMIC	9.540	Up-regulation
Atypical_PIKK_ATM_ATM_ST	Q13315	ATM	Q13315	ATM	S646	E641K	641	Missense	distal	-5	no	10.013	10.094	EPSD	COSMIC	9.540	Up-regulation
Atypical_PIKK_ATM_ATM_ST	Q13315	ATM	Q13315	ATM	S646	E649Q	649	Missense	distal	3	no	10.013	10.272	EPSD	COSMIC	9.540	Up-regulation
Atypical_PIKK_ATM_ATM_ST	Q13315	ATM	Q13315	ATM	S646	L653I	653	Missense	distal	7	no	10.013	10.025	EPSD	COSMIC	9.540	Up-regulation
Atypical_PIKK_ATM_ATM_ST	Q13315	ATM	Q13315	ATM	S646	S646L	646	Missense	central	0	yes	10.013	0.000	EPSD	COSMIC	9.540	Loss
Atypical_PIKK_ATM_ATM_ST	Q13315	ATM	Q13315	ATM	S775	M779I	779	Missense	distal	4	no	9.335	9.738	EPSD	COSMIC;GDSC;CCLE	9.540	Gain
Atypical_PIKK_ATM_ATM_ST	Q13315	ATM	Q13315	ATM	S775	F771S	771	Missense	distal	-4	no	9.335	10.734	EPSD	COSMIC	9.540	Gain
Atypical_PIKK_ATM_ATM_ST	Q13315	ATM	Q13315	ATM	S1137	N1140I	1140	Missense	distal	3	no	9.607	9.908	EPSD	COSMIC	9.540	Up-regulation
Atypical_PIKK_ATM_ATM_ST	Q13315	ATM	Q13315	ATM	S1137	E1133K	1133	Missense	distal	-4	no	9.607	8.635	EPSD	COSMIC;GDSC;CCLE	9.540	Loss
Atypical_PIKK_ATM_ATM_ST	Q13315	ATM	Q13315	ATM	S1137	E1133Q	1133	Missense	distal	-4	no	9.607	8.884	EPSD	COSMIC	9.540	Loss
Atypical_PIKK_ATM_ATM_ST	Q13315	ATM	Q13315	ATM	S1878	F1877L	1877	Missense	proximal	-1	no	14.356	14.647	EPSD	COSMIC	9.540	Up-regulation
Atypical_PIKK_ATM_ATM_ST	Q13315	ATM	Q13315	ATM	S1878	F1877Y	1877	Missense	proximal	-1	no	14.356	14.734	EPSD	COSMIC	9.540	Up-regulation
Atypical_PIKK_ATM_ATM_ST	Q13315	ATM	Q13315	ATM	S1878	T1880R	1880	Missense	proximal	2	no	14.356	13.620	EPSD	COSMIC	9.540	Down-regulation
Atypical_PIKK_ATM_ATM_ST	Q13315	ATM	Q13315	ATM	S1878	C1873Y	1873	Missense	distal	-5	no	14.356	14.287	EPSD	COSMIC	9.540	Down-regulation
Atypical_PIKK_ATM_ATM_ST	Q13315	ATM	Q13315	ATM	T1885	T1880R	1880	Missense	distal	-5	no	12.155	12.320	EPSD;PhosphoSitePlus	COSMIC	9.540	Up-regulation
Atypical_PIKK_ATM_ATM_ST	Q13315	ATM	Q13315	ATM	S1893	H1895Y	1895	Missense	proximal	2	no	11.705	11.526	EPSD;PhosphoSitePlus	COSMIC	9.540	Down-regulation
Atypical_PIKK_ATM_ATM_ST	Q13315	ATM	Q13315	ATM	S1981	I1986M	1986	Missense	distal	5	no	14.545	14.521	EPSD;PhosphoSitePlus	COSMIC	9.540	Down-regulation
Atypical_PIKK_ATM_ATM_ST	Q13315	ATM	Q13315	ATM	S1981	A1976S	1976	Missense	distal	-5	no	14.545	14.553	EPSD;PhosphoSitePlus	COSMIC	9.540	Up-regulation
Atypical_PIKK_ATM_ATM_ST	Q13315	ATM	Q13315	ATM	S1981	Q1982K	1982	Missense	proximal	1	no	14.545	7.697	EPSD;PhosphoSitePlus	COSMIC	9.540	Loss
Atypical_PIKK_ATM_ATM_ST	Q13315	ATM	Q13315	ATM	S1981	G1980R	1980	Missense	proximal	-1	no	14.545	14.362	EPSD;PhosphoSitePlus	COSMIC	9.540	Down-regulation
Atypical_PIKK_ATM_ATM_ST	Q13315	ATM	Q13315	ATM	S1981	E1978V	1978	Missense	distal	-3	no	14.545	15.123	EPSD;PhosphoSitePlus	COSMIC	9.540	Up-regulation
Atypical_PIKK_ATM_ATM_ST	Q13315	ATM	Q13315	ATM	S1981	S1983C	1983	Missense	proximal	2	no	14.545	13.292	EPSD;PhosphoSitePlus	COSMIC	9.540	Down-regulation
Atypical_PIKK_ATM_ATM_ST	Q13315	ATM	Q13315	ATM	S2000	L2004P	2004	Missense	distal	4	no	9.944	9.725	EPSD	COSMIC	9.540	Down-regulation
Atypical_PIKK_ATM_ATM_ST	Q13315	ATM	Q13315	ATM	S2000	L2005P	2005	Missense	distal	5	no	9.944	9.961	EPSD	COSMIC	9.540	Up-regulation
Atypical_PIKK_ATM_ATM_ST	Q13315	ATM	Q13315	ATM	S2000	L2005F	2005	Missense	distal	5	no	9.944	10.086	EPSD	COSMIC	9.540	Up-regulation
Atypical_PIKK_ATM_ATM_ST	Q13315	ATM	Q13315	ATM	S2000	L2004R	2004	Missense	distal	4	no	9.944	9.784	EPSD	COSMIC	9.540	Down-regulation
Atypical_PIKK_ATM_ATM_ST	Q13315	ATM	Q13315	ATM	S2000	I1999V	1999	Missense	proximal	-1	no	9.944	9.741	EPSD	COSMIC	9.540	Down-regulation
Atypical_PIKK_ATM_ATM_ST	Q13315	ATM	Q13315	ATM	S2000	E1995K	1995	Missense	distal	-5	no	9.944	10.026	EPSD	COSMIC	9.540	Up-regulation
Atypical_PIKK_ATM_ATM_ST	Q13315	ATM	Q13315	ATM	S2000	E1996K	1996	Missense	distal	-4	no	9.944	8.972	EPSD	COSMIC	9.540	Loss
Atypical_PIKK_ATM_ATM_ST	Q13315	ATM	Q13315	ATM	S2000	S2000R	2000	Missense	central	0	yes	9.944	0.000	EPSD	COSMIC	9.540	Loss
Atypical_PIKK_ATM_ATM_ST	Q13315	ATM	Q13315	ATM	S2000	K1994E	1994	Missense	distal	-6	no	9.944	10.245	EPSD	COSMIC	9.540	Up-regulation
Atypical_PIKK_ATM_ATM_ST	Q13315	ATM	Q13315	ATM	S2000	T1997I	1997	Missense	distal	-3	no	9.944	10.681	EPSD	COSMIC	9.540	Up-regulation
Atypical_PIKK_ATM_ATM_ST	Q13315	ATM	Q13315	ATM	S2199	V2201I	2201	Missense	proximal	2	no	10.633	10.841	EPSD	COSMIC	9.540	Up-regulation
Atypical_PIKK_ATM_ATM_ST	Q13315	ATM	Q13315	ATM	S2242	E2238V	2238	Missense	distal	-4	no	14.683	13.416	EPSD	COSMIC	9.540	Down-regulation
Atypical_PIKK_ATM_ATM_ST	Q13315	ATM	Q13315	ATM	S2242	D2240A	2240	Missense	proximal	-2	no	14.683	14.794	EPSD	COSMIC	9.540	Up-regulation
Atypical_PIKK_ATM_ATM_ST	Q13315	ATM	Q13315	ATM	S2242	E2245K	2245	Missense	distal	3	no	14.683	14.972	EPSD	COSMIC	9.540	Up-regulation
Atypical_PIKK_ATM_ATM_ST	Q13315	ATM	Q13315	ATM	S2242	E2238K	2238	Missense	distal	-4	no	14.683	13.711	EPSD	COSMIC	9.540	Down-regulation
Atypical_PIKK_ATM_ATM_ST	Q13315	ATM	Q13315	ATM	S2592	L2594F	2594	Missense	proximal	2	no	13.755	13.520	EPSD	COSMIC	9.540	Down-regulation
Atypical_PIKK_ATM_ATM_ST	Q13315	ATM	Q13315	ATM	S2592	D2597H	2597	Missense	distal	5	no	13.755	13.808	EPSD	COSMIC	9.540	Up-regulation
Atypical_PIKK_ATM_ATM_ST	Q13315	ATM	Q13315	ATM	S2592	Q2593R	2593	Missense	proximal	1	no	13.755	7.103	EPSD	COSMIC	9.540	Loss
Atypical_PIKK_ATM_ATM_ST	Q13315	ATM	Q13315	ATM	S2996	R2993Q	2993	Missense	distal	-3	no	11.474	10.699	EPSD;PhosphoSitePlus	COSMIC	9.540	Down-regulation
Atypical_PIKK_ATM_ATM_ST	Q13315	ATM	Q13315	ATM	S2996	S3001N	3001	Missense	distal	5	no	11.474	11.449	EPSD;PhosphoSitePlus	COSMIC	9.540	Down-regulation
Atypical_PIKK_ATM_ATM_ST	Q13315	ATM	Q13315	ATM	S2996	N2994S	2994	Missense	proximal	-2	no	11.474	11.654	EPSD;PhosphoSitePlus	COSMIC	9.540	Up-regulation
Atypical_PIKK_ATM_ATM_ST	Q13315	ATM	Q13315	ATM	S2996	N3003H	3003	Missense	distal	7	no	11.474	11.488	EPSD;PhosphoSitePlus	COSMIC	9.540	Up-regulation
Atypical_PIKK_ATM_ATM_ST	Q8N680	ZBTB2	Q13315	ATM	S115	S115I	115	Missense	central	0	yes	13.086	0.000	PhosphoSitePlus	COSMIC	9.540	Loss
Atypical_PIKK_ATM_ATM_ST	Q8N680	ZBTB2	Q13315	ATM	S115	A118T	118	Missense	distal	3	no	13.086	13.111	PhosphoSitePlus	COSMIC	9.540	Up-regulation
Atypical_PIKK_ATM_ATM_ST	Q8N680	ZBTB2	Q13315	ATM	S115	G117E	117	Missense	proximal	2	no	13.086	14.456	PhosphoSitePlus	COSMIC	9.540	Up-regulation
Atypical_PIKK_ATM_ATM_ST	Q8N680	ZBTB2	Q13315	ATM	S167	E173K	173	Missense	distal	6	no	14.026	13.981	EPSD	COSMIC;CCLE	9.540	Down-regulation
Atypical_PIKK_ATM_ATM_ST	Q8N680	ZBTB2	Q13315	ATM	S167	R160Q	160	Missense	distal	-7	no	14.026	14.226	EPSD	COSMIC	9.540	Up-regulation
Atypical_PIKK_ATM_ATM_ST	Q8N680	ZBTB2	Q13315	ATM	S175	E173K	173	Missense	proximal	-2	no	14.269	13.694	EPSD	COSMIC;CCLE	9.540	Down-regulation
Atypical_PIKK_ATM_ATM_ST	Q8N680	ZBTB2	Q13315	ATM	S178	E173K	173	Missense	distal	-5	no	13.761	13.843	EPSD	COSMIC;CCLE	9.540	Up-regulation
Atypical_PIKK_ATM_ATM_ST	Q8N680	ZBTB2	Q13315	ATM	S203	Q199L	199	Missense	distal	-4	no	10.550	10.055	EPSD	COSMIC;GDSC;CCLE	9.540	Down-regulation
Atypical_PIKK_ATM_ATM_ST	Q8N680	ZBTB2	Q13315	ATM	S284	G278A	278	Missense	distal	-6	no	15.839	16.020	EPSD	COSMIC;CCLE	9.540	Up-regulation
Atypical_PIKK_ATM_ATM_ST	Q8N680	ZBTB2	Q13315	ATM	S284	P280L	280	Missense	distal	-4	no	15.839	15.569	EPSD	COSMIC	9.540	Down-regulation
Atypical_PIKK_ATM_ATM_ST	Q8N680	ZBTB2	Q13315	ATM	S284	S283F	283	Missense	proximal	-1	no	15.839	15.413	EPSD	COSMIC	9.540	Down-regulation
Atypical_PIKK_ATM_ATM_ST	Q7L7X3	TAOK1	Q13315	ATM	S177	S174F	174	Missense	distal	-3	no	10.261	11.333	EPSD	COSMIC	9.540	Up-regulation
Atypical_PIKK_ATM_ATM_ST	Q7L7X3	TAOK1	Q13315	ATM	S421	D418Y	418	Missense	distal	-3	no	11.232	11.118	EPSD	COSMIC	9.540	Down-regulation
Atypical_PIKK_ATM_ATM_ST	Q7L7X3	TAOK1	Q13315	ATM	S421	S421F	421	Missense	central	0	yes	11.232	0.000	EPSD	COSMIC	9.540	Loss
Atypical_PIKK_ATM_ATM_ST	Q7L7X3	TAOK1	Q13315	ATM	S421	Q424K	424	Missense	distal	3	no	11.232	11.262	EPSD	COSMIC	9.540	Up-regulation
Atypical_PIKK_ATM_ATM_ST	Q7L7X3	TAOK1	Q13315	ATM	T502	L500I	500	Missense	proximal	-2	no	11.045	10.745	EPSD	COSMIC	9.540	Down-regulation
Atypical_PIKK_ATM_ATM_ST	Q7L7X3	TAOK1	Q13315	ATM	T576	E580K	580	Missense	distal	4	no	9.562	9.940	EPSD	COSMIC	9.540	Up-regulation
Atypical_PIKK_ATM_ATM_ST	Q7L7X3	TAOK1	Q13315	ATM	T576	E572K	572	Missense	distal	-4	no	9.562	8.590	EPSD	COSMIC	9.540	Loss
Atypical_PIKK_ATM_ATM_ST	Q7L7X3	TAOK1	Q13315	ATM	T643	D646N	646	Missense	distal	3	no	12.581	12.598	PhosphoSitePlus;EPSD	COSMIC	9.540	Up-regulation
Atypical_PIKK_ATM_ATM_ST	Q7L7X3	TAOK1	Q13315	ATM	T643	N639S	639	Missense	distal	-4	no	12.581	13.510	PhosphoSitePlus;EPSD	COSMIC	9.540	Up-regulation
Atypical_PIKK_ATM_ATM_ST	P04637	TP53	Q13315	ATM	S15	E11Q	11	Missense	distal	-4	no	17.866	17.143	EPSD;PhosphoSitePlus	COSMIC;GDSC;CCLE	9.540	Down-regulation
Atypical_PIKK_ATM_ATM_ST	P04637	TP53	Q13315	ATM	S15	S20L	20	Missense	distal	5	no	17.866	18.031	EPSD;PhosphoSitePlus	COSMIC	9.540	Up-regulation
Atypical_PIKK_ATM_ATM_ST	P04637	TP53	Q13315	ATM	S15	Q16L	16	Missense	proximal	1	no	17.866	11.510	EPSD;PhosphoSitePlus	COSMIC;GDSC;CCLE	9.540	Down-regulation
Atypical_PIKK_ATM_ATM_ST	P04637	TP53	Q13315	ATM	S15	P13S	13	Missense	proximal	-2	no	17.866	18.103	EPSD;PhosphoSitePlus	COSMIC	9.540	Up-regulation
Atypical_PIKK_ATM_ATM_ST	P04637	TP53	Q13315	ATM	S15	E17K	17	Missense	proximal	2	no	17.866	16.536	EPSD;PhosphoSitePlus	COSMIC	9.540	Down-regulation
Atypical_PIKK_ATM_ATM_ST	P04637	TP53	Q13315	ATM	S15	V10I	10	Missense	distal	-5	no	17.866	17.868	EPSD;PhosphoSitePlus	COSMIC	9.540	Up-regulation
Atypical_PIKK_ATM_ATM_ST	P04637	TP53	Q13315	ATM	S15	P8L	8	Missense	distal	-7	no	17.866	17.515	EPSD;PhosphoSitePlus	COSMIC	9.540	Down-regulation
Atypical_PIKK_ATM_ATM_ST	P04637	TP53	Q13315	ATM	S15	P8S	8	Missense	distal	-7	no	17.866	18.102	EPSD;PhosphoSitePlus	COSMIC	9.540	Up-regulation
Atypical_PIKK_ATM_ATM_ST	P04637	TP53	Q13315	ATM	S15	P13L	13	Missense	proximal	-2	no	17.866	17.714	EPSD;PhosphoSitePlus	COSMIC	9.540	Down-regulation
Atypical_PIKK_ATM_ATM_ST	P04637	TP53	Q13315	ATM	S15	V10G	10	Missense	distal	-5	no	17.866	17.808	EPSD;PhosphoSitePlus	COSMIC	9.540	Down-regulation
Atypical_PIKK_ATM_ATM_ST	P04637	TP53	Q13315	ATM	S15	T18A	18	Missense	distal	3	no	17.866	17.842	EPSD;PhosphoSitePlus	COSMIC	9.540	Down-regulation
Atypical_PIKK_ATM_ATM_ST	P04637	TP53	Q13315	ATM	S15	F19S	19	Missense	distal	4	no	17.866	17.039	EPSD;PhosphoSitePlus	COSMIC	9.540	Down-regulation
Atypical_PIKK_ATM_ATM_ST	P04637	TP53	Q13315	ATM	S15	E17V	17	Missense	proximal	2	no	17.866	16.464	EPSD;PhosphoSitePlus	COSMIC	9.540	Down-regulation
Atypical_PIKK_ATM_ATM_ST	P04637	TP53	Q13315	ATM	S15	S9G	9	Missense	distal	-6	no	17.866	17.665	EPSD;PhosphoSitePlus	COSMIC	9.540	Down-regulation
Atypical_PIKK_ATM_ATM_ST	P04637	TP53	Q13315	ATM	S15	T18I	18	Missense	distal	3	no	17.866	18.287	EPSD;PhosphoSitePlus	COSMIC	9.540	Up-regulation
Atypical_PIKK_ATM_ATM_ST	P04637	TP53	Q13315	ATM	S15	T18K	18	Missense	distal	3	no	17.866	17.899	EPSD;PhosphoSitePlus	COSMIC	9.540	Up-regulation
Atypical_PIKK_ATM_ATM_ST	P04637	TP53	Q13315	ATM	S15	T18R	18	Missense	distal	3	no	17.866	17.972	EPSD;PhosphoSitePlus	COSMIC	9.540	Up-regulation
Atypical_PIKK_ATM_ATM_ST	P04637	TP53	Q13315	ATM	S15	S15I	15	Missense	central	0	yes	17.866	0.000	EPSD;PhosphoSitePlus	COSMIC	9.540	Loss
Atypical_PIKK_ATM_ATM_ST	P04637	TP53	Q13315	ATM	S20	P13S	13	Missense	distal	-7	no	9.429	9.665	EPSD;PhosphoSitePlus	COSMIC	9.540	Gain
Atypical_PIKK_ATM_ATM_ST	P04637	TP53	Q13315	ATM	S20	F19S	19	Missense	proximal	-1	no	9.429	9.856	EPSD;PhosphoSitePlus	COSMIC	9.540	Gain
Atypical_PIKK_ATM_ATM_ST	P04637	TP53	Q13315	ATM	S20	E17V	17	Missense	distal	-3	no	9.429	10.007	EPSD;PhosphoSitePlus	COSMIC	9.540	Gain
Atypical_PIKK_ATM_ATM_ST	P04637	TP53	Q13315	ATM	S20	S15I	15	Missense	distal	-5	no	9.429	9.544	EPSD;PhosphoSitePlus	COSMIC	9.540	Gain
Atypical_PIKK_ATM_ATM_ST	P04637	TP53	Q13315	ATM	S37	M40I	40	Missense	distal	3	no	15.394	15.640	EPSD	COSMIC	9.540	Up-regulation
Atypical_PIKK_ATM_ATM_ST	P04637	TP53	Q13315	ATM	S37	V31I	31	Missense	distal	-6	no	15.394	15.250	EPSD	COSMIC;GDSC;CCLE	9.540	Down-regulation
Atypical_PIKK_ATM_ATM_ST	P04637	TP53	Q13315	ATM	S37	P36L	36	Missense	proximal	-1	no	15.394	15.551	EPSD	COSMIC;GDSC;CCLE	9.540	Up-regulation
Atypical_PIKK_ATM_ATM_ST	P04637	TP53	Q13315	ATM	S37	S33T	33	Missense	distal	-4	no	15.394	15.011	EPSD	COSMIC	9.540	Down-regulation
Atypical_PIKK_ATM_ATM_ST	P04637	TP53	Q13315	ATM	S37	D41N	41	Missense	distal	4	no	15.394	15.314	EPSD	COSMIC	9.540	Down-regulation
Atypical_PIKK_ATM_ATM_ST	P04637	TP53	Q13315	ATM	S37	L35F	35	Missense	proximal	-2	no	15.394	14.884	EPSD	COSMIC	9.540	Down-regulation
Atypical_PIKK_ATM_ATM_ST	P04637	TP53	Q13315	ATM	S37	Q38L	38	Missense	proximal	1	no	15.394	9.038	EPSD	COSMIC	9.540	Loss
Atypical_PIKK_ATM_ATM_ST	P04637	TP53	Q13315	ATM	S37	M44I	44	Missense	distal	7	no	15.394	15.392	EPSD	COSMIC	9.540	Down-regulation
Atypical_PIKK_ATM_ATM_ST	P04637	TP53	Q13315	ATM	S37	P36S	36	Missense	proximal	-1	no	15.394	15.686	EPSD	COSMIC;GDSC;CCLE	9.540	Up-regulation
Atypical_PIKK_ATM_ATM_ST	P04637	TP53	Q13315	ATM	S37	A39V	39	Missense	proximal	2	no	15.394	15.085	EPSD	COSMIC	9.540	Down-regulation
Atypical_PIKK_ATM_ATM_ST	P04637	TP53	Q13315	ATM	S37	A39S	39	Missense	proximal	2	no	15.394	15.977	EPSD	COSMIC	9.540	Up-regulation
Atypical_PIKK_ATM_ATM_ST	P04637	TP53	Q13315	ATM	S37	D42Y	42	Missense	distal	5	no	15.394	15.373	EPSD	COSMIC	9.540	Down-regulation
Atypical_PIKK_ATM_ATM_ST	P04637	TP53	Q13315	ATM	S37	M44R	44	Missense	distal	7	no	15.394	15.395	EPSD	COSMIC	9.540	Up-regulation
Atypical_PIKK_ATM_ATM_ST	P04637	TP53	Q13315	ATM	S37	M44V	44	Missense	distal	7	no	15.394	15.409	EPSD	COSMIC	9.540	Up-regulation
Atypical_PIKK_ATM_ATM_ST	P04637	TP53	Q13315	ATM	S37	N30K	30	Missense	distal	-7	no	15.394	15.268	EPSD	COSMIC	9.540	Down-regulation
Atypical_PIKK_ATM_ATM_ST	P04637	TP53	Q13315	ATM	S37	M44T	44	Missense	distal	7	no	15.394	15.377	EPSD	COSMIC	9.540	Down-regulation
Atypical_PIKK_ATM_ATM_ST	P04637	TP53	Q13315	ATM	S37	A39T	39	Missense	proximal	2	no	15.394	15.715	EPSD	COSMIC	9.540	Up-regulation
Atypical_PIKK_ATM_ATM_ST	P04637	TP53	Q13315	ATM	S37	L43F	43	Missense	distal	6	no	15.394	15.375	EPSD	COSMIC	9.540	Down-regulation
Atypical_PIKK_ATM_ATM_ST	P04637	TP53	Q13315	ATM	S37	D41H	41	Missense	distal	4	no	15.394	15.304	EPSD	COSMIC	9.540	Down-regulation
Atypical_PIKK_ATM_ATM_ST	P04637	TP53	Q13315	ATM	S37	P36R	36	Missense	proximal	-1	no	15.394	15.312	EPSD	COSMIC	9.540	Down-regulation
Atypical_PIKK_ATM_ATM_ST	P04637	TP53	Q13315	ATM	S37	L35R	35	Missense	proximal	-2	no	15.394	15.341	EPSD	COSMIC	9.540	Down-regulation
Atypical_PIKK_ATM_ATM_ST	P04637	TP53	Q13315	ATM	S37	L35H	35	Missense	proximal	-2	no	15.394	15.356	EPSD	COSMIC	9.540	Down-regulation
Atypical_PIKK_ATM_ATM_ST	P04637	TP53	Q13315	ATM	S37	L35P	35	Missense	proximal	-2	no	15.394	15.547	EPSD	COSMIC	9.540	Up-regulation
Atypical_PIKK_ATM_ATM_ST	P04637	TP53	Q13315	ATM	S37	L35I	35	Missense	proximal	-2	no	15.394	15.094	EPSD	COSMIC	9.540	Down-regulation
Atypical_PIKK_ATM_ATM_ST	P04637	TP53	Q13315	ATM	S37	L35V	35	Missense	proximal	-2	no	15.394	15.119	EPSD	COSMIC	9.540	Down-regulation
Atypical_PIKK_ATM_ATM_ST	P04637	TP53	Q13315	ATM	S37	D41E	41	Missense	distal	4	no	15.394	14.889	EPSD	COSMIC	9.540	Down-regulation
Atypical_PIKK_ATM_ATM_ST	P04637	TP53	Q13315	ATM	S46	M40I	40	Missense	distal	-6	no	12.775	12.619	PhosphoSitePlus;EPSD	COSMIC	9.540	Down-regulation
Atypical_PIKK_ATM_ATM_ST	P04637	TP53	Q13315	ATM	S46	W53C	53	Missense	distal	7	no	12.775	12.766	PhosphoSitePlus;EPSD	COSMIC	9.540	Down-regulation
Atypical_PIKK_ATM_ATM_ST	P04637	TP53	Q13315	ATM	S46	W53G	53	Missense	distal	7	no	12.775	12.755	PhosphoSitePlus;EPSD	COSMIC	9.540	Down-regulation
Atypical_PIKK_ATM_ATM_ST	P04637	TP53	Q13315	ATM	S46	S46F	46	Missense	central	0	yes	12.775	0.000	PhosphoSitePlus;EPSD	COSMIC	9.540	Loss
Atypical_PIKK_ATM_ATM_ST	P04637	TP53	Q13315	ATM	S46	D49Y	49	Missense	distal	3	no	12.775	12.833	PhosphoSitePlus;EPSD	COSMIC	9.540	Up-regulation
Atypical_PIKK_ATM_ATM_ST	P04637	TP53	Q13315	ATM	S46	P47L	47	Missense	proximal	1	no	12.775	11.220	PhosphoSitePlus;EPSD	COSMIC	9.540	Down-regulation
Atypical_PIKK_ATM_ATM_ST	P04637	TP53	Q13315	ATM	S46	D49H	49	Missense	distal	3	no	12.775	12.815	PhosphoSitePlus;EPSD	COSMIC;GDSC;CCLE	9.540	Up-regulation
Atypical_PIKK_ATM_ATM_ST	P04637	TP53	Q13315	ATM	S46	P47S	47	Missense	proximal	1	no	12.775	5.800	PhosphoSitePlus;EPSD	COSMIC	9.540	Loss
Atypical_PIKK_ATM_ATM_ST	P04637	TP53	Q13315	ATM	S46	D41N	41	Missense	distal	-5	no	12.775	12.958	PhosphoSitePlus;EPSD	COSMIC	9.540	Up-regulation
Atypical_PIKK_ATM_ATM_ST	P04637	TP53	Q13315	ATM	S46	D48H	48	Missense	proximal	2	no	12.775	11.713	PhosphoSitePlus;EPSD	COSMIC	9.540	Down-regulation
Atypical_PIKK_ATM_ATM_ST	P04637	TP53	Q13315	ATM	S46	D49N	49	Missense	distal	3	no	12.775	12.792	PhosphoSitePlus;EPSD	COSMIC	9.540	Up-regulation
Atypical_PIKK_ATM_ATM_ST	P04637	TP53	Q13315	ATM	S46	M44I	44	Missense	proximal	-2	no	12.775	12.524	PhosphoSitePlus;EPSD	COSMIC	9.540	Down-regulation
Atypical_PIKK_ATM_ATM_ST	P04637	TP53	Q13315	ATM	S46	Q52H	52	Missense	distal	6	no	12.775	12.764	PhosphoSitePlus;EPSD	COSMIC	9.540	Down-regulation
Atypical_PIKK_ATM_ATM_ST	P04637	TP53	Q13315	ATM	S46	D49V	49	Missense	distal	3	no	12.775	12.935	PhosphoSitePlus;EPSD	COSMIC	9.540	Up-regulation
Atypical_PIKK_ATM_ATM_ST	P04637	TP53	Q13315	ATM	S46	A39V	39	Missense	distal	-7	no	12.775	12.391	PhosphoSitePlus;EPSD	COSMIC	9.540	Down-regulation
Atypical_PIKK_ATM_ATM_ST	P04637	TP53	Q13315	ATM	S46	A39S	39	Missense	distal	-7	no	12.775	12.872	PhosphoSitePlus;EPSD	COSMIC	9.540	Up-regulation
Atypical_PIKK_ATM_ATM_ST	P04637	TP53	Q13315	ATM	S46	D42Y	42	Missense	distal	-4	no	12.775	11.678	PhosphoSitePlus;EPSD	COSMIC	9.540	Down-regulation
Atypical_PIKK_ATM_ATM_ST	P04637	TP53	Q13315	ATM	S46	M44R	44	Missense	proximal	-2	no	12.775	12.770	PhosphoSitePlus;EPSD	COSMIC	9.540	Down-regulation
Atypical_PIKK_ATM_ATM_ST	P04637	TP53	Q13315	ATM	S46	S46P	46	Missense	central	0	yes	12.775	0.000	PhosphoSitePlus;EPSD	COSMIC	9.540	Loss
Atypical_PIKK_ATM_ATM_ST	P04637	TP53	Q13315	ATM	S46	M44V	44	Missense	proximal	-2	no	12.775	12.549	PhosphoSitePlus;EPSD	COSMIC	9.540	Down-regulation
Atypical_PIKK_ATM_ATM_ST	P04637	TP53	Q13315	ATM	S46	L45P	45	Missense	proximal	-1	no	12.775	12.618	PhosphoSitePlus;EPSD	COSMIC	9.540	Down-regulation
Atypical_PIKK_ATM_ATM_ST	P04637	TP53	Q13315	ATM	S46	M44T	44	Missense	proximal	-2	no	12.775	13.125	PhosphoSitePlus;EPSD	COSMIC	9.540	Up-regulation
Atypical_PIKK_ATM_ATM_ST	P04637	TP53	Q13315	ATM	S46	A39T	39	Missense	distal	-7	no	12.775	12.791	PhosphoSitePlus;EPSD	COSMIC	9.540	Up-regulation
Atypical_PIKK_ATM_ATM_ST	P04637	TP53	Q13315	ATM	S46	L43F	43	Missense	distal	-3	no	12.775	13.638	PhosphoSitePlus;EPSD	COSMIC	9.540	Up-regulation
Atypical_PIKK_ATM_ATM_ST	P04637	TP53	Q13315	ATM	S46	D41H	41	Missense	distal	-5	no	12.775	13.034	PhosphoSitePlus;EPSD	COSMIC	9.540	Up-regulation
Atypical_PIKK_ATM_ATM_ST	P04637	TP53	Q13315	ATM	S46	D49E	49	Missense	distal	3	no	12.775	12.416	PhosphoSitePlus;EPSD	COSMIC	9.540	Down-regulation
Atypical_PIKK_ATM_ATM_ST	P04637	TP53	Q13315	ATM	S46	D49G	49	Missense	distal	3	no	12.775	12.722	PhosphoSitePlus;EPSD	COSMIC	9.540	Down-regulation
Atypical_PIKK_ATM_ATM_ST	P04637	TP53	Q13315	ATM	S46	D48A	48	Missense	proximal	2	no	12.775	11.812	PhosphoSitePlus;EPSD	COSMIC	9.540	Down-regulation
Atypical_PIKK_ATM_ATM_ST	P04637	TP53	Q13315	ATM	S46	D48Y	48	Missense	proximal	2	no	12.775	11.534	PhosphoSitePlus;EPSD	COSMIC	9.540	Down-regulation
Atypical_PIKK_ATM_ATM_ST	P04637	TP53	Q13315	ATM	S46	D48E	48	Missense	proximal	2	no	12.775	12.906	PhosphoSitePlus;EPSD	COSMIC	9.540	Up-regulation
Atypical_PIKK_ATM_ATM_ST	P04637	TP53	Q13315	ATM	S46	D49I	49	Missense	distal	3	no	12.775	13.093	PhosphoSitePlus;EPSD	COSMIC	9.540	Up-regulation
Atypical_PIKK_ATM_ATM_ST	P04637	TP53	Q13315	ATM	S46	D41E	41	Missense	distal	-5	no	12.775	12.821	PhosphoSitePlus;EPSD	COSMIC	9.540	Up-regulation
Atypical_PIKK_ATM_ATM_ST	P04637	TP53	Q13315	ATM	S99	S99F	99	Missense	central	0	yes	12.537	0.000	EPSD	COSMIC	9.540	Loss
Atypical_PIKK_ATM_ATM_ST	P04637	TP53	Q13315	ATM	S99	S96F	96	Missense	distal	-3	no	12.537	13.608	EPSD	COSMIC	9.540	Up-regulation
Atypical_PIKK_ATM_ATM_ST	P04637	TP53	Q13315	ATM	S99	P98S	98	Missense	proximal	-1	no	12.537	12.829	EPSD	COSMIC;CCLE	9.540	Up-regulation
Atypical_PIKK_ATM_ATM_ST	P04637	TP53	Q13315	ATM	S99	T102I	102	Missense	distal	3	no	12.537	12.958	EPSD	COSMIC	9.540	Up-regulation
Atypical_PIKK_ATM_ATM_ST	P04637	TP53	Q13315	ATM	S99	S94P	94	Missense	distal	-5	no	12.537	12.540	EPSD	COSMIC	9.540	Up-regulation
Atypical_PIKK_ATM_ATM_ST	P04637	TP53	Q13315	ATM	S99	K101R	101	Missense	proximal	2	no	12.537	12.359	EPSD	COSMIC	9.540	Down-regulation
Atypical_PIKK_ATM_ATM_ST	P04637	TP53	Q13315	ATM	S99	S94T	94	Missense	distal	-5	no	12.537	12.448	EPSD	COSMIC	9.540	Down-regulation
Atypical_PIKK_ATM_ATM_ST	P04637	TP53	Q13315	ATM	S99	P98L	98	Missense	proximal	-1	no	12.537	12.694	EPSD	COSMIC;GDSC;CCLE	9.540	Up-regulation
Atypical_PIKK_ATM_ATM_ST	P04637	TP53	Q13315	ATM	S99	S95F	95	Missense	distal	-4	no	12.537	11.138	EPSD	COSMIC;CCLE	9.540	Down-regulation
Atypical_PIKK_ATM_ATM_ST	P04637	TP53	Q13315	ATM	S99	S96C	96	Missense	distal	-3	no	12.537	12.704	EPSD	COSMIC	9.540	Up-regulation
Atypical_PIKK_ATM_ATM_ST	P04637	TP53	Q13315	ATM	S99	S106I	106	Missense	distal	7	no	12.537	12.568	EPSD	COSMIC	9.540	Up-regulation
Atypical_PIKK_ATM_ATM_ST	P04637	TP53	Q13315	ATM	S99	P98F	98	Missense	proximal	-1	no	12.537	12.402	EPSD	COSMIC	9.540	Down-regulation
Atypical_PIKK_ATM_ATM_ST	P04637	TP53	Q13315	ATM	S99	T102P	102	Missense	distal	3	no	12.537	12.608	EPSD	COSMIC	9.540	Up-regulation
Atypical_PIKK_ATM_ATM_ST	P04637	TP53	Q13315	ATM	S99	S94L	94	Missense	distal	-5	no	12.537	12.559	EPSD	COSMIC	9.540	Up-regulation
Atypical_PIKK_ATM_ATM_ST	P04637	TP53	Q13315	ATM	S99	S96P	96	Missense	distal	-3	no	12.537	12.733	EPSD	COSMIC	9.540	Up-regulation
Atypical_PIKK_ATM_ATM_ST	P04637	TP53	Q13315	ATM	S99	P98T	98	Missense	proximal	-1	no	12.537	12.839	EPSD	COSMIC	9.540	Up-regulation
Atypical_PIKK_ATM_ATM_ST	P04637	TP53	Q13315	ATM	S99	S96Y	96	Missense	distal	-3	no	12.537	12.669	EPSD	COSMIC	9.540	Up-regulation
Atypical_PIKK_ATM_ATM_ST	P04637	TP53	Q13315	ATM	S99	S99P	99	Missense	central	0	yes	12.537	0.000	EPSD	COSMIC	9.540	Loss
Atypical_PIKK_ATM_ATM_ST	P04637	TP53	Q13315	ATM	S99	V97I	97	Missense	proximal	-2	no	12.537	12.512	EPSD	COSMIC	9.540	Down-regulation
Atypical_PIKK_ATM_ATM_ST	P04637	TP53	Q13315	ATM	S99	Q104H	104	Missense	distal	5	no	12.537	12.623	EPSD	COSMIC	9.540	Up-regulation
Atypical_PIKK_ATM_ATM_ST	P04637	TP53	Q13315	ATM	S99	L93M	93	Missense	distal	-6	no	12.537	12.580	EPSD	COSMIC	9.540	Up-regulation
Atypical_PIKK_ATM_ATM_ST	P04637	TP53	Q13315	ATM	S99	K101N	101	Missense	proximal	2	no	12.537	12.715	EPSD	COSMIC	9.540	Up-regulation
Atypical_PIKK_ATM_ATM_ST	P04637	TP53	Q13315	ATM	S99	V97A	97	Missense	proximal	-2	no	12.537	13.014	EPSD	COSMIC	9.540	Up-regulation
Atypical_PIKK_ATM_ATM_ST	P04637	TP53	Q13315	ATM	S99	P92A	92	Missense	distal	-7	no	12.537	12.676	EPSD	COSMIC	9.540	Up-regulation
Atypical_PIKK_ATM_ATM_ST	P04637	TP53	Q13315	ATM	S99	Q104L	104	Missense	distal	5	no	12.537	12.648	EPSD	COSMIC	9.540	Up-regulation
Atypical_PIKK_ATM_ATM_ST	P04637	TP53	Q13315	ATM	S99	P92L	92	Missense	distal	-7	no	12.537	12.185	EPSD	COSMIC	9.540	Down-regulation
Atypical_PIKK_ATM_ATM_ST	P04637	TP53	Q13315	ATM	S99	L93P	93	Missense	distal	-6	no	12.537	12.766	EPSD	COSMIC	9.540	Up-regulation
Atypical_PIKK_ATM_ATM_ST	P04637	TP53	Q13315	ATM	S99	L93F	93	Missense	distal	-6	no	12.537	12.293	EPSD	COSMIC	9.540	Down-regulation
Atypical_PIKK_ATM_ATM_ST	P04637	TP53	Q13315	ATM	S99	L93H	93	Missense	distal	-6	no	12.537	12.645	EPSD	COSMIC	9.540	Up-regulation
Atypical_PIKK_ATM_ATM_ST	P04637	TP53	Q13315	ATM	S99	S95Y	95	Missense	distal	-4	no	12.537	11.436	EPSD	COSMIC	9.540	Down-regulation
Atypical_PIKK_ATM_ATM_ST	P04637	TP53	Q13315	ATM	S106	G108C	108	Missense	proximal	2	no	10.952	10.557	EPSD	COSMIC	9.540	Down-regulation
Atypical_PIKK_ATM_ATM_ST	P04637	TP53	Q13315	ATM	S106	S99F	99	Missense	distal	-7	no	10.952	10.123	EPSD	COSMIC	9.540	Down-regulation
Atypical_PIKK_ATM_ATM_ST	P04637	TP53	Q13315	ATM	S106	R110H	110	Missense	distal	4	no	10.952	10.888	EPSD	COSMIC	9.540	Down-regulation
Atypical_PIKK_ATM_ATM_ST	P04637	TP53	Q13315	ATM	S106	Y107Q	107	Missense	proximal	1	no	10.952	16.668	EPSD	COSMIC	9.540	Up-regulation
Atypical_PIKK_ATM_ATM_ST	P04637	TP53	Q13315	ATM	S106	T102I	102	Missense	distal	-4	no	10.952	10.624	EPSD	COSMIC	9.540	Down-regulation
Atypical_PIKK_ATM_ATM_ST	P04637	TP53	Q13315	ATM	S106	K101R	101	Missense	distal	-5	no	10.952	11.112	EPSD	COSMIC	9.540	Up-regulation
Atypical_PIKK_ATM_ATM_ST	P04637	TP53	Q13315	ATM	S106	Y107C	107	Missense	proximal	1	no	10.952	4.458	EPSD	COSMIC	9.540	Loss
Atypical_PIKK_ATM_ATM_ST	P04637	TP53	Q13315	ATM	S106	S106I	106	Missense	central	0	yes	10.952	0.000	EPSD	COSMIC	9.540	Loss
Atypical_PIKK_ATM_ATM_ST	P04637	TP53	Q13315	ATM	S106	Y107H	107	Missense	proximal	1	no	10.952	1.759	EPSD	COSMIC	9.540	Loss
Atypical_PIKK_ATM_ATM_ST	P04637	TP53	Q13315	ATM	S106	T102P	102	Missense	distal	-4	no	10.952	10.666	EPSD	COSMIC	9.540	Down-regulation
Atypical_PIKK_ATM_ATM_ST	P04637	TP53	Q13315	ATM	S106	L111M	111	Missense	distal	5	no	10.952	10.973	EPSD	COSMIC	9.540	Up-regulation
Atypical_PIKK_ATM_ATM_ST	P04637	TP53	Q13315	ATM	S106	F109I	109	Missense	distal	3	no	10.952	10.872	EPSD	COSMIC	9.540	Down-regulation
Atypical_PIKK_ATM_ATM_ST	P04637	TP53	Q13315	ATM	S106	G108D	108	Missense	proximal	2	no	10.952	12.191	EPSD	COSMIC	9.540	Up-regulation
Atypical_PIKK_ATM_ATM_ST	P04637	TP53	Q13315	ATM	S106	S99P	99	Missense	distal	-7	no	10.952	10.716	EPSD	COSMIC	9.540	Down-regulation
Atypical_PIKK_ATM_ATM_ST	P04637	TP53	Q13315	ATM	S106	Q104H	104	Missense	proximal	-2	no	10.952	10.649	EPSD	COSMIC	9.540	Down-regulation
Atypical_PIKK_ATM_ATM_ST	P04637	TP53	Q13315	ATM	S106	K101N	101	Missense	distal	-5	no	10.952	11.008	EPSD	COSMIC	9.540	Up-regulation
Atypical_PIKK_ATM_ATM_ST	P04637	TP53	Q13315	ATM	S106	Q104L	104	Missense	proximal	-2	no	10.952	10.687	EPSD	COSMIC	9.540	Down-regulation
Atypical_PIKK_ATM_ATM_ST	P04637	TP53	Q13315	ATM	S106	R110S	110	Missense	distal	4	no	10.952	10.771	EPSD	COSMIC	9.540	Down-regulation
Atypical_PIKK_ATM_ATM_ST	P04637	TP53	Q13315	ATM	S106	G112E	112	Missense	distal	6	no	10.952	10.996	EPSD	COSMIC	9.540	Up-regulation
Atypical_PIKK_ATM_ATM_ST	P04637	TP53	Q13315	ATM	S106	G112C	112	Missense	distal	6	no	10.952	10.899	EPSD	COSMIC	9.540	Down-regulation
Atypical_PIKK_ATM_ATM_ST	P04637	TP53	Q13315	ATM	S106	G112S	112	Missense	distal	6	no	10.952	10.971	EPSD	COSMIC	9.540	Up-regulation
Atypical_PIKK_ATM_ATM_ST	P04637	TP53	Q13315	ATM	S106	G112V	112	Missense	distal	6	no	10.952	10.947	EPSD	COSMIC	9.540	Down-regulation
Atypical_PIKK_ATM_ATM_ST	P04637	TP53	Q13315	ATM	S106	G112D	112	Missense	distal	6	no	10.952	10.949	EPSD	COSMIC	9.540	Down-regulation
Atypical_PIKK_ATM_ATM_ST	P04637	TP53	Q13315	ATM	S106	G112R	112	Missense	distal	6	no	10.952	10.954	EPSD	COSMIC	9.540	Up-regulation
Atypical_PIKK_ATM_ATM_ST	P04637	TP53	Q13315	ATM	S106	G112A	112	Missense	distal	6	no	10.952	10.978	EPSD	COSMIC	9.540	Up-regulation
Atypical_PIKK_ATM_ATM_ST	P04637	TP53	Q13315	ATM	S106	G112F	112	Missense	distal	6	no	10.952	10.895	EPSD	COSMIC	9.540	Down-regulation
Atypical_PIKK_ATM_ATM_ST	P04637	TP53	Q13315	ATM	S106	F113S	113	Missense	distal	7	no	10.952	10.892	EPSD	COSMIC;CCLE	9.540	Down-regulation
Atypical_PIKK_ATM_ATM_ST	P04637	TP53	Q13315	ATM	S106	F113P	113	Missense	distal	7	no	10.952	10.911	EPSD	COSMIC	9.540	Down-regulation
Atypical_PIKK_ATM_ATM_ST	P04637	TP53	Q13315	ATM	S127	C124W	124	Missense	distal	-3	no	9.567	9.710	EPSD	COSMIC	9.540	Up-regulation
Atypical_PIKK_ATM_ATM_ST	P04637	TP53	Q13315	ATM	S127	C124F	124	Missense	distal	-3	no	9.567	10.471	EPSD	COSMIC	9.540	Up-regulation
Atypical_PIKK_ATM_ATM_ST	P04637	TP53	Q13315	ATM	S127	C124S	124	Missense	distal	-3	no	9.567	9.399	EPSD	COSMIC	9.540	Loss
Atypical_PIKK_ATM_ATM_ST	P04637	TP53	Q13315	ATM	S127	S127A	127	Missense	central	0	yes	9.567	0.000	EPSD	COSMIC	9.540	Loss
Atypical_PIKK_ATM_ATM_ST	P04637	TP53	Q13315	ATM	S127	S127L	127	Missense	central	0	yes	9.567	0.000	EPSD	COSMIC	9.540	Loss
Atypical_PIKK_ATM_ATM_ST	P04637	TP53	Q13315	ATM	S127	C124T	124	Missense	distal	-3	no	9.567	9.331	EPSD	COSMIC	9.540	Loss
Atypical_PIKK_ATM_ATM_ST	P04637	TP53	Q13315	ATM	S127	S127I	127	Missense	central	0	yes	9.567	0.000	EPSD	COSMIC	9.540	Loss
Atypical_PIKK_ATM_ATM_ST	P04637	TP53	Q13315	ATM	S127	S127G	127	Missense	central	0	yes	9.567	0.000	EPSD	COSMIC	9.540	Loss
Atypical_PIKK_ATM_ATM_ST	P04637	TP53	Q13315	ATM	S127	N131H	131	Missense	distal	4	no	9.567	9.557	EPSD	COSMIC	9.540	Down-regulation
Atypical_PIKK_ATM_ATM_ST	P04637	TP53	Q13315	ATM	S127	N131D	131	Missense	distal	4	no	9.567	9.647	EPSD	COSMIC	9.540	Up-regulation
Atypical_PIKK_ATM_ATM_ST	P04637	TP53	Q13315	ATM	S127	T125I	125	Missense	proximal	-2	no	9.567	8.965	EPSD	COSMIC	9.540	Loss
Atypical_PIKK_ATM_ATM_ST	P04637	TP53	Q13315	ATM	S127	F134I	134	Missense	distal	7	no	9.567	9.538	EPSD	COSMIC	9.540	Loss
Atypical_PIKK_ATM_ATM_ST	P04637	TP53	Q13315	ATM	S127	K120T	120	Missense	distal	-7	no	9.567	9.798	EPSD	COSMIC	9.540	Up-regulation
Atypical_PIKK_ATM_ATM_ST	P04637	TP53	Q13315	ATM	S127	F134S	134	Missense	distal	7	no	9.567	9.507	EPSD	COSMIC	9.540	Loss
Atypical_PIKK_ATM_ATM_ST	P04637	TP53	Q13315	ATM	S127	T125K	125	Missense	proximal	-2	no	9.567	9.260	EPSD	COSMIC	9.540	Loss
Atypical_PIKK_ATM_ATM_ST	P04637	TP53	Q13315	ATM	S127	M133I	133	Missense	distal	6	no	9.567	9.555	EPSD	COSMIC	9.540	Down-regulation
Atypical_PIKK_ATM_ATM_ST	P04637	TP53	Q13315	ATM	S127	N131K	131	Missense	distal	4	no	9.567	9.519	EPSD	COSMIC;CCLE	9.540	Loss
Atypical_PIKK_ATM_ATM_ST	P04637	TP53	Q13315	ATM	S127	P128S	128	Missense	proximal	1	no	9.567	2.592	EPSD	COSMIC	9.540	Loss
Atypical_PIKK_ATM_ATM_ST	P04637	TP53	Q13315	ATM	S127	M133L	133	Missense	distal	6	no	9.567	9.540	EPSD	COSMIC	9.540	Down-regulation
Atypical_PIKK_ATM_ATM_ST	P04637	TP53	Q13315	ATM	S127	A129T	129	Missense	proximal	2	no	9.567	9.888	EPSD	COSMIC	9.540	Up-regulation
Atypical_PIKK_ATM_ATM_ST	P04637	TP53	Q13315	ATM	S127	T123I	123	Missense	distal	-4	no	9.567	9.238	EPSD	COSMIC	9.540	Loss
Atypical_PIKK_ATM_ATM_ST	P04637	TP53	Q13315	ATM	S127	A129G	129	Missense	proximal	2	no	9.567	9.291	EPSD	COSMIC	9.540	Loss
Atypical_PIKK_ATM_ATM_ST	P04637	TP53	Q13315	ATM	S127	K132W	132	Missense	distal	5	no	9.567	9.752	EPSD	COSMIC	9.540	Up-regulation
Atypical_PIKK_ATM_ATM_ST	P04637	TP53	Q13315	ATM	S127	A129V	129	Missense	proximal	2	no	9.567	9.258	EPSD	COSMIC	9.540	Loss
Atypical_PIKK_ATM_ATM_ST	P04637	TP53	Q13315	ATM	S127	P128A	128	Missense	proximal	1	no	9.567	7.495	EPSD	COSMIC	9.540	Loss
Atypical_PIKK_ATM_ATM_ST	P04637	TP53	Q13315	ATM	S127	L130I	130	Missense	distal	3	no	9.567	9.786	EPSD	COSMIC	9.540	Up-regulation
Atypical_PIKK_ATM_ATM_ST	P04637	TP53	Q13315	ATM	S127	S121F	121	Missense	distal	-6	no	9.567	9.035	EPSD	COSMIC	9.540	Loss
Atypical_PIKK_ATM_ATM_ST	P04637	TP53	Q13315	ATM	S127	A129D	129	Missense	proximal	2	no	9.567	10.530	EPSD	COSMIC	9.540	Up-regulation
Atypical_PIKK_ATM_ATM_ST	P04637	TP53	Q13315	ATM	S127	K120Q	120	Missense	distal	-7	no	9.567	9.680	EPSD	COSMIC	9.540	Up-regulation
Atypical_PIKK_ATM_ATM_ST	P04637	TP53	Q13315	ATM	S127	T125S	125	Missense	proximal	-2	no	9.567	9.655	EPSD	COSMIC	9.540	Up-regulation
Atypical_PIKK_ATM_ATM_ST	P04637	TP53	Q13315	ATM	S127	P128L	128	Missense	proximal	1	no	9.567	8.012	EPSD	COSMIC	9.540	Loss
Atypical_PIKK_ATM_ATM_ST	P04637	TP53	Q13315	ATM	S127	V122L	122	Missense	distal	-5	no	9.567	9.476	EPSD	COSMIC	9.540	Loss
Atypical_PIKK_ATM_ATM_ST	P04637	TP53	Q13315	ATM	S127	C124L	124	Missense	distal	-3	no	9.567	9.608	EPSD	COSMIC	9.540	Up-regulation
Atypical_PIKK_ATM_ATM_ST	P04637	TP53	Q13315	ATM	S127	N131T	131	Missense	distal	4	no	9.567	9.527	EPSD	COSMIC	9.540	Loss
Atypical_PIKK_ATM_ATM_ST	P04637	TP53	Q13315	ATM	S127	M133V	133	Missense	distal	6	no	9.567	9.572	EPSD	COSMIC	9.540	Up-regulation
Atypical_PIKK_ATM_ATM_ST	P04637	TP53	Q13315	ATM	S269	F270Y	270	Missense	proximal	1	no	5.967	10.488	EPSD	COSMIC	9.540	Gain
Atypical_PIKK_ATM_ATM_ST	P04637	TP53	Q13315	ATM	S378	R379P	379	Missense	proximal	1	no	8.282	10.132	EPSD	COSMIC	9.540	Gain
Atypical_PIKK_ATM_ATM_ST	P04637	TP53	Q13315	ATM	S392	P390L	390	Missense	proximal	-2	no	9.915	9.762	EPSD	COSMIC	9.540	Down-regulation
Atypical_PIKK_ATM_ATM_ST	P04637	TP53	Q13315	ATM	S392	S392P	392	Missense	central	0	yes	9.915	0.000	EPSD	COSMIC	9.540	Loss
Atypical_PIKK_ATM_ATM_ST	P04637	TP53	Q13315	ATM	S392	K386N	386	Missense	distal	-6	no	9.915	9.913	EPSD	COSMIC	9.540	Down-regulation
Atypical_PIKK_ATM_ATM_ST	P04637	TP53	Q13315	ATM	S392	G389E	389	Missense	distal	-3	no	9.915	9.478	EPSD	COSMIC	9.540	Loss
Atypical_PIKK_ATM_ATM_ST	P04637	TP53	Q13315	ATM	S392	S392L	392	Missense	central	0	yes	9.915	0.000	EPSD	COSMIC	9.540	Loss
Atypical_PIKK_ATM_ATM_ST	P04637	TP53	Q13315	ATM	S392	D391N	391	Missense	proximal	-1	no	9.915	9.914	EPSD	COSMIC	9.540	Down-regulation
Atypical_PIKK_ATM_ATM_ST	P04637	TP53	Q13315	ATM	S392	D391Y	391	Missense	proximal	-1	no	9.915	9.921	EPSD	COSMIC	9.540	Up-regulation
Atypical_PIKK_ATM_ATM_ST	P04637	TP53	Q13315	ATM	S392	G389V	389	Missense	distal	-3	no	9.915	10.055	EPSD	COSMIC	9.540	Up-regulation
Atypical_PIKK_ATM_ATM_ST	Q9H3D4	TP63	Q13315	ATM	S51	E48K	48	Missense	distal	-3	no	11.008	11.075	EPSD	COSMIC	9.540	Up-regulation
Atypical_PIKK_ATM_ATM_ST	Q9H3D4	TP63	Q13315	ATM	S51	S51N	51	Missense	central	0	yes	11.008	0.000	EPSD	COSMIC	9.540	Loss
Atypical_PIKK_ATM_ATM_ST	Q9H3D4	TP63	Q13315	ATM	S51	F55V	55	Missense	distal	4	no	11.008	10.486	EPSD	COSMIC	9.540	Down-regulation
Atypical_PIKK_ATM_ATM_ST	Q9H3D4	TP63	Q13315	ATM	S51	F55L	55	Missense	distal	4	no	11.008	10.522	EPSD	COSMIC	9.540	Down-regulation
Atypical_PIKK_ATM_ATM_ST	Q9H3D4	TP63	Q13315	ATM	S51	L50F	50	Missense	proximal	-1	no	11.008	10.717	EPSD	COSMIC	9.540	Down-regulation
Atypical_PIKK_ATM_ATM_ST	Q9H3D4	TP63	Q13315	ATM	S51	P52L	52	Missense	proximal	1	no	11.008	9.454	EPSD	COSMIC	9.540	Loss
Atypical_PIKK_ATM_ATM_ST	Q9H3D4	TP63	Q13315	ATM	S51	H57R	57	Missense	distal	6	no	11.008	11.024	EPSD	COSMIC	9.540	Up-regulation
Atypical_PIKK_ATM_ATM_ST	Q9H3D4	TP63	Q13315	ATM	S162	T169N	169	Missense	distal	7	no	9.666	9.665	EPSD	COSMIC	9.540	Down-regulation
Atypical_PIKK_ATM_ATM_ST	Q9H3D4	TP63	Q13315	ATM	S162	P161S	161	Missense	proximal	-1	no	9.666	9.959	EPSD	COSMIC	9.540	Up-regulation
Atypical_PIKK_ATM_ATM_ST	Q9H3D4	TP63	Q13315	ATM	S162	L159F	159	Missense	distal	-3	no	9.666	10.529	EPSD	COSMIC	9.540	Up-regulation
Atypical_PIKK_ATM_ATM_ST	Q9H3D4	TP63	Q13315	ATM	S162	S160C	160	Missense	proximal	-2	no	9.666	9.204	EPSD	COSMIC	9.540	Loss
Atypical_PIKK_ATM_ATM_ST	Q9H3D4	TP63	Q13315	ATM	S162	T169I	169	Missense	distal	7	no	9.666	9.681	EPSD	COSMIC	9.540	Up-regulation
Atypical_PIKK_ATM_ATM_ST	Q9H3D4	TP63	Q13315	ATM	S162	P166H	166	Missense	distal	4	no	9.666	9.661	EPSD	COSMIC	9.540	Down-regulation
Atypical_PIKK_ATM_ATM_ST	Q9H3D4	TP63	Q13315	ATM	S162	N168S	168	Missense	distal	6	no	9.666	9.677	EPSD	COSMIC	9.540	Up-regulation
Atypical_PIKK_ATM_ATM_ST	Q9H3D4	TP63	Q13315	ATM	S162	P161L	161	Missense	proximal	-1	no	9.666	9.823	EPSD	COSMIC	9.540	Up-regulation
Atypical_PIKK_ATM_ATM_ST	Q9H3D4	TP63	Q13315	ATM	T374	R376S	376	Missense	proximal	2	no	8.776	9.773	EPSD	COSMIC	9.540	Gain
Atypical_PIKK_ATM_ATM_ST	Q9H3D4	TP63	Q13315	ATM	S455	S462L	462	Missense	distal	7	no	10.300	10.319	EPSD	COSMIC	9.540	Up-regulation
Atypical_PIKK_ATM_ATM_ST	Q9H3D4	TP63	Q13315	ATM	S455	S462A	462	Missense	distal	7	no	10.300	10.331	EPSD	COSMIC	9.540	Up-regulation
Atypical_PIKK_ATM_ATM_ST	Q9H3D4	TP63	Q13315	ATM	S455	Q454H	454	Missense	proximal	-1	no	10.300	10.163	EPSD	COSMIC	9.540	Down-regulation
Atypical_PIKK_ATM_ATM_ST	Q9H3D4	TP63	Q13315	ATM	S455	Q454R	454	Missense	proximal	-1	no	10.300	9.992	EPSD	COSMIC	9.540	Down-regulation
Atypical_PIKK_ATM_ATM_ST	Q9H3D4	TP63	Q13315	ATM	S455	Q450R	450	Missense	distal	-5	no	10.300	10.509	EPSD	COSMIC	9.540	Up-regulation
Atypical_PIKK_ATM_ATM_ST	Q9H3D4	TP63	Q13315	ATM	S455	Q450H	450	Missense	distal	-5	no	10.300	10.482	EPSD	COSMIC	9.540	Up-regulation
Atypical_PIKK_ATM_ATM_ST	Q9H3D4	TP63	Q13315	ATM	S455	S457G	457	Missense	proximal	2	no	10.300	9.441	EPSD	COSMIC	9.540	Loss
Atypical_PIKK_ATM_ATM_ST	Q9H3D4	TP63	Q13315	ATM	S479	P484H	484	Missense	distal	5	no	15.147	15.105	PhosphoSitePlus	COSMIC	9.540	Down-regulation
Atypical_PIKK_ATM_ATM_ST	Q9H3D4	TP63	Q13315	ATM	S479	N483K	483	Missense	distal	4	no	15.147	15.099	PhosphoSitePlus	COSMIC	9.540	Down-regulation
Atypical_PIKK_ATM_ATM_ST	Q9H3D4	TP63	Q13315	ATM	S479	N483D	483	Missense	distal	4	no	15.147	15.227	PhosphoSitePlus	COSMIC	9.540	Up-regulation
Atypical_PIKK_ATM_ATM_ST	Q9H3D4	TP63	Q13315	ATM	S479	V478L	478	Missense	proximal	-1	no	15.147	15.435	PhosphoSitePlus	COSMIC	9.540	Up-regulation
Atypical_PIKK_ATM_ATM_ST	Q9H3D4	TP63	Q13315	ATM	S479	M472I	472	Missense	distal	-7	no	15.147	14.957	PhosphoSitePlus	COSMIC	9.540	Down-regulation
Atypical_PIKK_ATM_ATM_ST	O15111	CHUK	Q13315	ATM	T23	M17T	17	Missense	distal	-6	no	9.451	9.627	EPSD	COSMIC	9.540	Gain
Atypical_PIKK_ATM_ATM_ST	O15111	CHUK	Q13315	ATM	S473	K479E	479	Missense	distal	6	no	13.086	13.131	PhosphoSitePlus	COSMIC	9.540	Up-regulation
Atypical_PIKK_ATM_ATM_ST	Q9BUR4	WRAP53	Q13315	ATM	T6	T3P	3	Missense	distal	-3	no	10.869	11.133	EPSD	COSMIC	9.540	Up-regulation
Atypical_PIKK_ATM_ATM_ST	Q9BUR4	WRAP53	Q13315	ATM	S54	D56N	56	Missense	proximal	2	no	10.205	9.184	EPSD	COSMIC;GDSC;CCLE	9.540	Loss
Atypical_PIKK_ATM_ATM_ST	Q8IX03	WWC1	Q13315	ATM	S141	V134I	134	Missense	distal	-7	no	14.203	14.019	EPSD	COSMIC;CCLE	9.540	Down-regulation
Atypical_PIKK_ATM_ATM_ST	Q8IX03	WWC1	Q13315	ATM	S141	K138T	138	Missense	distal	-3	no	14.203	14.228	EPSD	COSMIC	9.540	Up-regulation
Atypical_PIKK_ATM_ATM_ST	Q8IX03	WWC1	Q13315	ATM	S141	S141F	141	Missense	central	0	yes	14.203	0.000	EPSD	COSMIC	9.540	Loss
Atypical_PIKK_ATM_ATM_ST	Q8IX03	WWC1	Q13315	ATM	S876	E873K	873	Missense	distal	-3	no	12.923	12.990	EPSD	COSMIC	9.540	Up-regulation
Atypical_PIKK_ATM_ATM_ST	Q8IX03	WWC1	Q13315	ATM	S876	D869H	869	Missense	distal	-7	no	12.923	12.832	EPSD	COSMIC	9.540	Down-regulation
Atypical_PIKK_ATM_ATM_ST	Q8IX03	WWC1	Q13315	ATM	S876	G881E	881	Missense	distal	5	no	12.923	12.574	EPSD	COSMIC	9.540	Down-regulation
Atypical_PIKK_ATM_ATM_ST	Q8IX03	WWC1	Q13315	ATM	S876	G881V	881	Missense	distal	5	no	12.923	12.957	EPSD	COSMIC	9.540	Up-regulation
Atypical_PIKK_ATM_ATM_ST	Q8IX03	WWC1	Q13315	ATM	S914	P913S	913	Missense	proximal	-1	no	15.951	16.244	EPSD	COSMIC	9.540	Up-regulation
Atypical_PIKK_ATM_ATM_ST	Q8IX03	WWC1	Q13315	ATM	S927	K928Q	928	Missense	proximal	1	no	8.450	15.298	EPSD	COSMIC	9.540	Gain
Atypical_PIKK_ATM_ATM_ST	Q8IX03	WWC1	Q13315	ATM	S947	T951I	951	Missense	distal	4	no	9.252	9.827	EPSD	COSMIC	9.540	Gain
Atypical_PIKK_ATM_ATM_ST	P37275	ZEB1	Q13315	ATM	S33	N30I	30	Missense	distal	-3	no	8.981	9.678	EPSD	COSMIC	9.540	Gain
Atypical_PIKK_ATM_ATM_ST	P37275	ZEB1	Q13315	ATM	S155	E159K	159	Missense	distal	4	no	9.263	9.640	EPSD	COSMIC;GDSC;CCLE	9.540	Gain
Atypical_PIKK_ATM_ATM_ST	P37275	ZEB1	Q13315	ATM	T162	L169F	169	Missense	distal	7	no	9.748	9.789	EPSD	COSMIC	9.540	Up-regulation
Atypical_PIKK_ATM_ATM_ST	P37275	ZEB1	Q13315	ATM	T162	L169S	169	Missense	distal	7	no	9.748	9.729	EPSD	COSMIC	9.540	Down-regulation
Atypical_PIKK_ATM_ATM_ST	P37275	ZEB1	Q13315	ATM	T162	E159K	159	Missense	distal	-3	no	9.748	9.815	EPSD	COSMIC;GDSC;CCLE	9.540	Up-regulation
Atypical_PIKK_ATM_ATM_ST	P37275	ZEB1	Q13315	ATM	T162	S155N	155	Missense	distal	-7	no	9.748	9.561	EPSD	COSMIC	9.540	Down-regulation
Atypical_PIKK_ATM_ATM_ST	P37275	ZEB1	Q13315	ATM	T162	D158N	158	Missense	distal	-4	no	9.748	8.824	EPSD	COSMIC	9.540	Loss
Atypical_PIKK_ATM_ATM_ST	P37275	ZEB1	Q13315	ATM	T162	L169M	169	Missense	distal	7	no	9.748	9.762	EPSD	COSMIC	9.540	Up-regulation
Atypical_PIKK_ATM_ATM_ST	P37275	ZEB1	Q13315	ATM	S167	L169F	169	Missense	proximal	2	no	13.065	12.830	EPSD	COSMIC	9.540	Down-regulation
Atypical_PIKK_ATM_ATM_ST	P37275	ZEB1	Q13315	ATM	S167	C172F	172	Missense	distal	5	no	13.065	13.145	EPSD	COSMIC	9.540	Up-regulation
Atypical_PIKK_ATM_ATM_ST	P37275	ZEB1	Q13315	ATM	S167	P173L	173	Missense	distal	6	no	13.065	13.020	EPSD	COSMIC	9.540	Down-regulation
Atypical_PIKK_ATM_ATM_ST	P37275	ZEB1	Q13315	ATM	S167	L169S	169	Missense	proximal	2	no	13.065	14.309	EPSD	COSMIC	9.540	Up-regulation
Atypical_PIKK_ATM_ATM_ST	P37275	ZEB1	Q13315	ATM	S167	P173S	173	Missense	distal	6	no	13.065	13.076	EPSD	COSMIC	9.540	Up-regulation
Atypical_PIKK_ATM_ATM_ST	P37275	ZEB1	Q13315	ATM	S167	L169M	169	Missense	proximal	2	no	13.065	13.252	EPSD	COSMIC	9.540	Up-regulation
Atypical_PIKK_ATM_ATM_ST	P37275	ZEB1	Q13315	ATM	S167	L170F	170	Missense	distal	3	no	13.065	13.365	EPSD	COSMIC	9.540	Up-regulation
Atypical_PIKK_ATM_ATM_ST	P37275	ZEB1	Q13315	ATM	T243	E244Q	244	Missense	proximal	1	no	5.188	11.085	EPSD	COSMIC	9.540	Gain
Atypical_PIKK_ATM_ATM_ST	P37275	ZEB1	Q13315	ATM	S278	H279Y	279	Missense	proximal	1	no	0.595	9.788	EPSD	COSMIC	9.540	Gain
Atypical_PIKK_ATM_ATM_ST	P37275	ZEB1	Q13315	ATM	S280	H279Y	279	Missense	proximal	-1	no	9.387	9.542	EPSD	COSMIC	9.540	Gain
Atypical_PIKK_ATM_ATM_ST	P37275	ZEB1	Q13315	ATM	S282	K275T	275	Missense	distal	-7	no	10.704	10.936	EPSD	COSMIC	9.540	Up-regulation
Atypical_PIKK_ATM_ATM_ST	P37275	ZEB1	Q13315	ATM	S282	S278Y	278	Missense	distal	-4	no	10.704	9.604	EPSD	COSMIC	9.540	Down-regulation
Atypical_PIKK_ATM_ATM_ST	P37275	ZEB1	Q13315	ATM	S282	R276C	276	Missense	distal	-6	no	10.704	10.505	EPSD	COSMIC	9.540	Down-regulation
Atypical_PIKK_ATM_ATM_ST	P37275	ZEB1	Q13315	ATM	S282	H279Y	279	Missense	distal	-3	no	10.704	10.742	EPSD	COSMIC	9.540	Up-regulation
Atypical_PIKK_ATM_ATM_ST	P37275	ZEB1	Q13315	ATM	S282	S282F	282	Missense	central	0	yes	10.704	0.000	EPSD	COSMIC	9.540	Loss
Atypical_PIKK_ATM_ATM_ST	P37275	ZEB1	Q13315	ATM	S282	S278P	278	Missense	distal	-4	no	10.704	10.035	EPSD	COSMIC	9.540	Down-regulation
Atypical_PIKK_ATM_ATM_ST	P37275	ZEB1	Q13315	ATM	S282	S278F	278	Missense	distal	-4	no	10.704	9.306	EPSD	COSMIC	9.540	Loss
Atypical_PIKK_ATM_ATM_ST	P37275	ZEB1	Q13315	ATM	S282	F277C	277	Missense	distal	-5	no	10.704	10.474	EPSD	COSMIC	9.540	Down-regulation
Atypical_PIKK_ATM_ATM_ST	P37275	ZEB1	Q13315	ATM	S282	G281V	281	Missense	proximal	-1	no	10.704	10.473	EPSD	COSMIC	9.540	Down-regulation
Atypical_PIKK_ATM_ATM_ST	P37275	ZEB1	Q13315	ATM	S282	Y283H	283	Missense	proximal	1	no	10.704	1.511	EPSD	COSMIC	9.540	Loss
Atypical_PIKK_ATM_ATM_ST	P37275	ZEB1	Q13315	ATM	S282	H279N	279	Missense	distal	-3	no	10.704	10.583	EPSD	COSMIC	9.540	Down-regulation
Atypical_PIKK_ATM_ATM_ST	P37275	ZEB1	Q13315	ATM	S309	P314L	314	Missense	distal	5	no	11.175	11.157	EPSD	COSMIC	9.540	Down-regulation
Atypical_PIKK_ATM_ATM_ST	P37275	ZEB1	Q13315	ATM	S309	P314S	314	Missense	distal	5	no	11.175	10.993	EPSD	COSMIC	9.540	Down-regulation
Atypical_PIKK_ATM_ATM_ST	P37275	ZEB1	Q13315	ATM	S309	T308I	308	Missense	proximal	-1	no	11.175	10.944	EPSD	COSMIC	9.540	Down-regulation
Atypical_PIKK_ATM_ATM_ST	P37275	ZEB1	Q13315	ATM	S309	L316F	316	Missense	distal	7	no	11.175	11.215	EPSD	COSMIC	9.540	Up-regulation
Atypical_PIKK_ATM_ATM_ST	P37275	ZEB1	Q13315	ATM	S309	L316R	316	Missense	distal	7	no	11.175	11.190	EPSD	COSMIC	9.540	Up-regulation
Atypical_PIKK_ATM_ATM_ST	P37275	ZEB1	Q13315	ATM	S309	S313L	313	Missense	distal	4	no	11.175	11.516	EPSD	COSMIC	9.540	Up-regulation
Atypical_PIKK_ATM_ATM_ST	P37275	ZEB1	Q13315	ATM	S309	K307Q	307	Missense	proximal	-2	no	11.175	11.445	EPSD	COSMIC;GDSC;CCLE	9.540	Up-regulation
Atypical_PIKK_ATM_ATM_ST	P37275	ZEB1	Q13315	ATM	S312	S313L	313	Missense	proximal	1	no	4.651	10.071	EPSD	COSMIC	9.540	Gain
Atypical_PIKK_ATM_ATM_ST	P37275	ZEB1	Q13315	ATM	S313	P314L	314	Missense	proximal	1	no	9.714	8.160	EPSD	COSMIC	9.540	Loss
Atypical_PIKK_ATM_ATM_ST	P37275	ZEB1	Q13315	ATM	S313	P320R	320	Missense	distal	7	no	9.714	9.730	EPSD	COSMIC	9.540	Up-regulation
Atypical_PIKK_ATM_ATM_ST	P37275	ZEB1	Q13315	ATM	S313	P314S	314	Missense	proximal	1	no	9.714	2.739	EPSD	COSMIC	9.540	Loss
Atypical_PIKK_ATM_ATM_ST	P37275	ZEB1	Q13315	ATM	S313	T308I	308	Missense	distal	-5	no	9.714	9.917	EPSD	COSMIC	9.540	Up-regulation
Atypical_PIKK_ATM_ATM_ST	P37275	ZEB1	Q13315	ATM	S313	L316F	316	Missense	distal	3	no	9.714	10.014	EPSD	COSMIC	9.540	Up-regulation
Atypical_PIKK_ATM_ATM_ST	P37275	ZEB1	Q13315	ATM	S313	L316R	316	Missense	distal	3	no	9.714	9.618	EPSD	COSMIC	9.540	Down-regulation
Atypical_PIKK_ATM_ATM_ST	P37275	ZEB1	Q13315	ATM	S313	S313L	313	Missense	central	0	yes	9.714	0.000	EPSD	COSMIC	9.540	Loss
Atypical_PIKK_ATM_ATM_ST	P37275	ZEB1	Q13315	ATM	S313	K307Q	307	Missense	distal	-6	no	9.714	9.791	EPSD	COSMIC;GDSC;CCLE	9.540	Up-regulation
Atypical_PIKK_ATM_ATM_ST	P37275	ZEB1	Q13315	ATM	S313	A318S	318	Missense	distal	5	no	9.714	9.667	EPSD	COSMIC	9.540	Down-regulation
Atypical_PIKK_ATM_ATM_ST	P37275	ZEB1	Q13315	ATM	S313	P320S	320	Missense	distal	7	no	9.714	9.696	EPSD	COSMIC	9.540	Down-regulation
Atypical_PIKK_ATM_ATM_ST	P37275	ZEB1	Q13315	ATM	S319	L316F	316	Missense	distal	-3	no	8.838	9.700	EPSD	COSMIC	9.540	Gain
Atypical_PIKK_ATM_ATM_ST	P37275	ZEB1	Q13315	ATM	T324	R325Q	325	Missense	proximal	1	no	5.707	12.358	EPSD	COSMIC;GDSC;CCLE	9.540	Gain
Atypical_PIKK_ATM_ATM_ST	P37275	ZEB1	Q13315	ATM	S447	G452C	452	Missense	distal	5	no	10.921	10.969	EPSD	COSMIC;GDSC;CCLE	9.540	Up-regulation
Atypical_PIKK_ATM_ATM_ST	P37275	ZEB1	Q13315	ATM	S447	N445S	445	Missense	proximal	-2	no	10.921	11.100	EPSD	COSMIC	9.540	Up-regulation
Atypical_PIKK_ATM_ATM_ST	P37275	ZEB1	Q13315	ATM	S447	S447L	447	Missense	central	0	yes	10.921	0.000	EPSD	COSMIC	9.540	Loss
Atypical_PIKK_ATM_ATM_ST	P37275	ZEB1	Q13315	ATM	S447	E440K	440	Missense	distal	-7	no	10.921	10.252	EPSD	COSMIC	9.540	Down-regulation
Atypical_PIKK_ATM_ATM_ST	P37275	ZEB1	Q13315	ATM	S447	Q451E	451	Missense	distal	4	no	10.921	10.589	EPSD	COSMIC	9.540	Down-regulation
Atypical_PIKK_ATM_ATM_ST	P37275	ZEB1	Q13315	ATM	S447	G453C	453	Missense	distal	6	no	10.921	10.867	EPSD	COSMIC	9.540	Down-regulation
Atypical_PIKK_ATM_ATM_ST	P37275	ZEB1	Q13315	ATM	S583	P588S	588	Missense	distal	5	no	10.937	10.755	EPSD	COSMIC	9.540	Down-regulation
Atypical_PIKK_ATM_ATM_ST	P37275	ZEB1	Q13315	ATM	S583	G580V	580	Missense	distal	-3	no	10.937	11.077	EPSD	COSMIC	9.540	Up-regulation
Atypical_PIKK_ATM_ATM_ST	P37275	ZEB1	Q13315	ATM	S585	P588S	588	Missense	distal	3	no	14.131	13.979	PhosphoSitePlus	COSMIC	9.540	Down-regulation
Atypical_PIKK_ATM_ATM_ST	P37275	ZEB1	Q13315	ATM	S585	N591Y	591	Missense	distal	6	no	14.131	14.100	PhosphoSitePlus	COSMIC	9.540	Down-regulation
Atypical_PIKK_ATM_ATM_ST	P37275	ZEB1	Q13315	ATM	S585	G580V	580	Missense	distal	-5	no	14.131	14.190	PhosphoSitePlus	COSMIC	9.540	Up-regulation
Atypical_PIKK_ATM_ATM_ST	P37275	ZEB1	Q13315	ATM	S646	S646Y	646	Missense	central	0	yes	9.613	0.000	EPSD	COSMIC	9.540	Loss
Atypical_PIKK_ATM_ATM_ST	P37275	ZEB1	Q13315	ATM	S646	P647S	647	Missense	proximal	1	no	9.613	2.637	EPSD	COSMIC	9.540	Loss
Atypical_PIKK_ATM_ATM_ST	P37275	ZEB1	Q13315	ATM	S646	P649S	649	Missense	distal	3	no	9.613	9.461	EPSD	COSMIC	9.540	Loss
Atypical_PIKK_ATM_ATM_ST	P37275	ZEB1	Q13315	ATM	S664	E669K	669	Missense	distal	5	no	9.365	9.540	EPSD	COSMIC	9.540	Gain
Atypical_PIKK_ATM_ATM_ST	P37275	ZEB1	Q13315	ATM	S664	E669D	669	Missense	distal	5	no	9.365	9.622	EPSD	COSMIC	9.540	Gain
Atypical_PIKK_ATM_ATM_ST	P37275	ZEB1	Q13315	ATM	S679	S686L	686	Missense	distal	7	no	9.945	9.964	EPSD	COSMIC	9.540	Up-regulation
Atypical_PIKK_ATM_ATM_ST	P37275	ZEB1	Q13315	ATM	S679	T674K	674	Missense	distal	-5	no	9.945	9.950	EPSD	COSMIC	9.540	Up-regulation
Atypical_PIKK_ATM_ATM_ST	P37275	ZEB1	Q13315	ATM	S679	S679I	679	Missense	central	0	yes	9.945	0.000	EPSD	COSMIC	9.540	Loss
Atypical_PIKK_ATM_ATM_ST	P37275	ZEB1	Q13315	ATM	S679	T674S	674	Missense	distal	-5	no	9.945	10.033	EPSD	COSMIC	9.540	Up-regulation
Atypical_PIKK_ATM_ATM_ST	P37275	ZEB1	Q13315	ATM	S679	L681F	681	Missense	proximal	2	no	9.945	9.710	EPSD	COSMIC	9.540	Down-regulation
Atypical_PIKK_ATM_ATM_ST	P37275	ZEB1	Q13315	ATM	S679	N676H	676	Missense	distal	-3	no	9.945	10.066	EPSD	COSMIC	9.540	Up-regulation
Atypical_PIKK_ATM_ATM_ST	P37275	ZEB1	Q13315	ATM	S679	S686F	686	Missense	distal	7	no	9.945	10.005	EPSD	COSMIC	9.540	Up-regulation
Atypical_PIKK_ATM_ATM_ST	P37275	ZEB1	Q13315	ATM	S679	P680S	680	Missense	proximal	1	no	9.945	2.969	EPSD	COSMIC	9.540	Loss
Atypical_PIKK_ATM_ATM_ST	P37275	ZEB1	Q13315	ATM	S686	V688A	688	Missense	proximal	2	no	9.463	9.772	EPSD	COSMIC	9.540	Gain
Atypical_PIKK_ATM_ATM_ST	P37275	ZEB1	Q13315	ATM	S686	L681F	681	Missense	distal	-5	no	9.463	9.763	EPSD	COSMIC	9.540	Gain
Atypical_PIKK_ATM_ATM_ST	P37275	ZEB1	Q13315	ATM	T702	S706L	706	Missense	distal	4	no	10.969	11.311	EPSD	COSMIC	9.540	Up-regulation
Atypical_PIKK_ATM_ATM_ST	P37275	ZEB1	Q13315	ATM	T702	S700I	700	Missense	proximal	-2	no	10.969	10.280	EPSD	COSMIC	9.540	Down-regulation
Atypical_PIKK_ATM_ATM_ST	P37275	ZEB1	Q13315	ATM	T702	P705T	705	Missense	distal	3	no	10.969	10.898	EPSD	COSMIC	9.540	Down-regulation
Atypical_PIKK_ATM_ATM_ST	P37275	ZEB1	Q13315	ATM	T702	R699I	699	Missense	distal	-3	no	10.969	10.899	EPSD	COSMIC	9.540	Down-regulation
Atypical_PIKK_ATM_ATM_ST	P37275	ZEB1	Q13315	ATM	T702	T702A	702	Missense	central	0	yes	10.969	0.000	EPSD	COSMIC	9.540	Loss
Atypical_PIKK_ATM_ATM_ST	P37275	ZEB1	Q13315	ATM	T702	S701I	701	Missense	proximal	-1	no	10.969	10.748	EPSD	COSMIC	9.540	Down-regulation
Atypical_PIKK_ATM_ATM_ST	P37275	ZEB1	Q13315	ATM	S704	S706L	706	Missense	proximal	2	no	10.144	8.900	EPSD	COSMIC	9.540	Loss
Atypical_PIKK_ATM_ATM_ST	P37275	ZEB1	Q13315	ATM	S704	S700I	700	Missense	distal	-4	no	10.144	9.433	EPSD	COSMIC	9.540	Loss
Atypical_PIKK_ATM_ATM_ST	P37275	ZEB1	Q13315	ATM	S704	P705T	705	Missense	proximal	1	no	10.144	5.137	EPSD	COSMIC	9.540	Loss
Atypical_PIKK_ATM_ATM_ST	P37275	ZEB1	Q13315	ATM	S704	R699I	699	Missense	distal	-5	no	10.144	10.182	EPSD	COSMIC	9.540	Up-regulation
Atypical_PIKK_ATM_ATM_ST	P37275	ZEB1	Q13315	ATM	S704	T702A	702	Missense	proximal	-2	no	10.144	10.044	EPSD	COSMIC	9.540	Down-regulation
Atypical_PIKK_ATM_ATM_ST	P37275	ZEB1	Q13315	ATM	S704	S701I	701	Missense	distal	-3	no	10.144	10.814	EPSD	COSMIC	9.540	Up-regulation
Atypical_PIKK_ATM_ATM_ST	P37275	ZEB1	Q13315	ATM	T716	Q717K	717	Missense	proximal	1	no	12.764	5.916	EPSD	COSMIC	9.540	Loss
Atypical_PIKK_ATM_ATM_ST	P37275	ZEB1	Q13315	ATM	T716	R714K	714	Missense	proximal	-2	no	12.764	12.812	EPSD	COSMIC	9.540	Up-regulation
Atypical_PIKK_ATM_ATM_ST	P37275	ZEB1	Q13315	ATM	T716	G718D	718	Missense	proximal	2	no	12.764	14.002	EPSD	COSMIC	9.540	Up-regulation
Atypical_PIKK_ATM_ATM_ST	P37275	ZEB1	Q13315	ATM	T716	A723T	723	Missense	distal	7	no	12.764	12.750	EPSD	COSMIC	9.540	Down-regulation
Atypical_PIKK_ATM_ATM_ST	P37275	ZEB1	Q13315	ATM	T716	S712T	712	Missense	distal	-4	no	12.764	12.381	EPSD	COSMIC	9.540	Down-regulation
Atypical_PIKK_ATM_ATM_ST	P37275	ZEB1	Q13315	ATM	S850	Y843H	843	Missense	distal	-7	no	11.233	11.215	EPSD	COSMIC	9.540	Down-regulation
Atypical_PIKK_ATM_ATM_ST	P37275	ZEB1	Q13315	ATM	S850	Q854H	854	Missense	distal	4	no	11.233	11.317	EPSD	COSMIC	9.540	Up-regulation
Atypical_PIKK_ATM_ATM_ST	P37275	ZEB1	Q13315	ATM	S850	P851S	851	Missense	proximal	1	no	11.233	4.258	EPSD	COSMIC	9.540	Loss
Atypical_PIKK_ATM_ATM_ST	P37275	ZEB1	Q13315	ATM	S850	E855A	855	Missense	distal	5	no	11.233	11.452	EPSD	COSMIC	9.540	Up-regulation
Atypical_PIKK_ATM_ATM_ST	P37275	ZEB1	Q13315	ATM	S850	E855K	855	Missense	distal	5	no	11.233	11.408	EPSD	COSMIC	9.540	Up-regulation
Atypical_PIKK_ATM_ATM_ST	P37275	ZEB1	Q13315	ATM	S850	T848M	848	Missense	proximal	-2	no	11.233	10.883	EPSD	COSMIC	9.540	Down-regulation
Atypical_PIKK_ATM_ATM_ST	P37275	ZEB1	Q13315	ATM	S850	Y843C	843	Missense	distal	-7	no	11.233	10.854	EPSD	COSMIC	9.540	Down-regulation
Atypical_PIKK_ATM_ATM_ST	P37275	ZEB1	Q13315	ATM	S850	S850N	850	Missense	central	0	yes	11.233	0.000	EPSD	COSMIC	9.540	Loss
Atypical_PIKK_ATM_ATM_ST	P37275	ZEB1	Q13315	ATM	S887	Q884H	884	Missense	distal	-3	no	12.085	12.215	EPSD	COSMIC	9.540	Up-regulation
Atypical_PIKK_ATM_ATM_ST	P37275	ZEB1	Q13315	ATM	S887	D886Y	886	Missense	proximal	-1	no	12.085	12.091	EPSD	COSMIC	9.540	Up-regulation
Atypical_PIKK_ATM_ATM_ST	P37275	ZEB1	Q13315	ATM	S887	E882D	882	Missense	distal	-5	no	12.085	12.039	EPSD	COSMIC	9.540	Down-regulation
Atypical_PIKK_ATM_ATM_ST	P37275	ZEB1	Q13315	ATM	S887	T890P	890	Missense	distal	3	no	12.085	12.157	EPSD	COSMIC	9.540	Up-regulation
Atypical_PIKK_ATM_ATM_ST	P37275	ZEB1	Q13315	ATM	T890	Q884H	884	Missense	distal	-6	no	9.705	9.562	EPSD	COSMIC	9.540	Down-regulation
Atypical_PIKK_ATM_ATM_ST	P37275	ZEB1	Q13315	ATM	T890	R897W	897	Missense	distal	7	no	9.705	9.731	EPSD	COSMIC;CCLE	9.540	Up-regulation
Atypical_PIKK_ATM_ATM_ST	P37275	ZEB1	Q13315	ATM	T890	R897L	897	Missense	distal	7	no	9.705	9.689	EPSD	COSMIC	9.540	Down-regulation
Atypical_PIKK_ATM_ATM_ST	P37275	ZEB1	Q13315	ATM	T890	D886Y	886	Missense	distal	-4	no	9.705	8.608	EPSD	COSMIC	9.540	Loss
Atypical_PIKK_ATM_ATM_ST	P37275	ZEB1	Q13315	ATM	T890	R897Q	897	Missense	distal	7	no	9.705	9.680	EPSD	COSMIC	9.540	Down-regulation
Atypical_PIKK_ATM_ATM_ST	P37275	ZEB1	Q13315	ATM	T890	T890P	890	Missense	central	0	yes	9.705	0.000	EPSD	COSMIC	9.540	Loss
Atypical_PIKK_ATM_ATM_ST	P37275	ZEB1	Q13315	ATM	S974	Q977K	977	Missense	distal	3	no	10.813	10.843	EPSD	COSMIC	9.540	Up-regulation
Atypical_PIKK_ATM_ATM_ST	P37275	ZEB1	Q13315	ATM	S974	R968C	968	Missense	distal	-6	no	10.813	10.614	EPSD	COSMIC	9.540	Down-regulation
Atypical_PIKK_ATM_ATM_ST	P37275	ZEB1	Q13315	ATM	S974	S972Y	972	Missense	proximal	-2	no	10.813	10.643	EPSD	COSMIC	9.540	Down-regulation
Atypical_PIKK_ATM_ATM_ST	P37275	ZEB1	Q13315	ATM	S974	G973W	973	Missense	proximal	-1	no	10.813	10.627	EPSD	COSMIC	9.540	Down-regulation
Atypical_PIKK_ATM_ATM_ST	P37275	ZEB1	Q13315	ATM	S974	M979I	979	Missense	distal	5	no	10.813	10.838	EPSD	COSMIC	9.540	Up-regulation
Atypical_PIKK_ATM_ATM_ST	P37275	ZEB1	Q13315	ATM	S974	S976F	976	Missense	proximal	2	no	10.813	9.335	EPSD	COSMIC	9.540	Loss
Atypical_PIKK_ATM_ATM_ST	P37275	ZEB1	Q13315	ATM	S976	Q977K	977	Missense	proximal	1	no	13.728	6.880	EPSD	COSMIC	9.540	Loss
Atypical_PIKK_ATM_ATM_ST	P37275	ZEB1	Q13315	ATM	S976	S972Y	972	Missense	distal	-4	no	13.728	12.627	EPSD	COSMIC	9.540	Down-regulation
Atypical_PIKK_ATM_ATM_ST	P37275	ZEB1	Q13315	ATM	S976	G973W	973	Missense	distal	-3	no	13.728	13.761	EPSD	COSMIC	9.540	Up-regulation
Atypical_PIKK_ATM_ATM_ST	P37275	ZEB1	Q13315	ATM	S976	M979I	979	Missense	distal	3	no	13.728	13.973	EPSD	COSMIC	9.540	Up-regulation
Atypical_PIKK_ATM_ATM_ST	P37275	ZEB1	Q13315	ATM	S976	R982C	982	Missense	distal	6	no	13.728	13.674	EPSD	COSMIC	9.540	Down-regulation
Atypical_PIKK_ATM_ATM_ST	P37275	ZEB1	Q13315	ATM	S976	S976F	976	Missense	central	0	yes	13.728	0.000	EPSD	COSMIC	9.540	Loss
Atypical_PIKK_ATM_ATM_ST	P37275	ZEB1	Q13315	ATM	T996	E999K	999	Missense	distal	3	no	9.513	9.802	EPSD	COSMIC	9.540	Gain
Atypical_PIKK_ATM_ATM_ST	P37275	ZEB1	Q13315	ATM	T996	D994N	994	Missense	proximal	-2	no	9.513	9.632	EPSD	COSMIC	9.540	Gain
Atypical_PIKK_ATM_ATM_ST	P37275	ZEB1	Q13315	ATM	T996	D994E	994	Missense	proximal	-2	no	9.513	9.992	EPSD	COSMIC	9.540	Gain
Atypical_PIKK_ATM_ATM_ST	P37275	ZEB1	Q13315	ATM	T996	A1001V	1001	Missense	distal	5	no	9.513	9.678	EPSD	COSMIC	9.540	Gain
Atypical_PIKK_ATM_ATM_ST	P37275	ZEB1	Q13315	ATM	T996	E1000K	1000	Missense	distal	4	no	9.513	9.891	EPSD	COSMIC	9.540	Gain
Atypical_PIKK_ATM_ATM_ST	P37275	ZEB1	Q13315	ATM	S1018	A1013E	1013	Missense	distal	-5	no	11.269	11.112	EPSD	COSMIC	9.540	Down-regulation
Atypical_PIKK_ATM_ATM_ST	P37275	ZEB1	Q13315	ATM	S1018	E1024K	1024	Missense	distal	6	no	11.269	11.224	EPSD	COSMIC	9.540	Down-regulation
Atypical_PIKK_ATM_ATM_ST	P37275	ZEB1	Q13315	ATM	S1018	A1015V	1015	Missense	distal	-3	no	11.269	12.133	EPSD	COSMIC	9.540	Up-regulation
Atypical_PIKK_ATM_ATM_ST	P37275	ZEB1	Q13315	ATM	S1018	R1025K	1025	Missense	distal	7	no	11.269	11.257	EPSD	COSMIC	9.540	Down-regulation
Atypical_PIKK_ATM_ATM_ST	P37275	ZEB1	Q13315	ATM	S1018	R1014S	1014	Missense	distal	-4	no	11.269	12.080	EPSD	COSMIC	9.540	Up-regulation
Atypical_PIKK_ATM_ATM_ST	P37275	ZEB1	Q13315	ATM	S1018	S1022L	1022	Missense	distal	4	no	11.269	11.611	EPSD	COSMIC	9.540	Up-regulation
Atypical_PIKK_ATM_ATM_ST	P37275	ZEB1	Q13315	ATM	S1018	D1021Y	1021	Missense	distal	3	no	11.269	11.327	EPSD	COSMIC	9.540	Up-regulation
Atypical_PIKK_ATM_ATM_ST	P37275	ZEB1	Q13315	ATM	S1018	D1023N	1023	Missense	distal	5	no	11.269	11.158	EPSD	COSMIC	9.540	Down-regulation
Atypical_PIKK_ATM_ATM_ST	P37275	ZEB1	Q13315	ATM	S1036	E1037Q	1037	Missense	proximal	1	no	7.881	13.777	EPSD	COSMIC	9.540	Gain
Atypical_PIKK_ATM_ATM_ST	P37275	ZEB1	Q13315	ATM	S1100	E1099G	1099	Missense	proximal	-1	no	14.055	13.653	EPSD	COSMIC	9.540	Down-regulation
Atypical_PIKK_ATM_ATM_ST	P37275	ZEB1	Q13315	ATM	S1100	Q1101H	1101	Missense	proximal	1	no	14.055	-0.854	EPSD	COSMIC	9.540	Loss
Atypical_PIKK_ATM_ATM_ST	P37275	ZEB1	Q13315	ATM	S1100	A1102S	1102	Missense	proximal	2	no	14.055	14.638	EPSD	COSMIC	9.540	Up-regulation
Atypical_PIKK_ATM_ATM_ST	P37275	ZEB1	Q13315	ATM	S1100	S1103N	1103	Missense	distal	3	no	14.055	14.255	EPSD	COSMIC	9.540	Up-regulation
Atypical_PIKK_ATM_ATM_ST	P37275	ZEB1	Q13315	ATM	S1100	G1106R	1106	Missense	distal	6	no	14.055	14.056	EPSD	COSMIC	9.540	Up-regulation
Atypical_PIKK_ATM_ATM_ST	P37275	ZEB1	Q13315	ATM	S1100	G1106V	1106	Missense	distal	6	no	14.055	14.049	EPSD	COSMIC	9.540	Down-regulation
Atypical_PIKK_ATM_ATM_ST	P37275	ZEB1	Q13315	ATM	S1100	A1102T	1102	Missense	proximal	2	no	14.055	14.376	EPSD	COSMIC	9.540	Up-regulation
Atypical_PIKK_ATM_ATM_ST	P37275	ZEB1	Q13315	ATM	S1100	S1104N	1104	Missense	distal	4	no	14.055	14.182	EPSD	COSMIC	9.540	Up-regulation
Atypical_PIKK_ATM_ATM_ST	P37275	ZEB1	Q13315	ATM	S1100	E1099K	1099	Missense	proximal	-1	no	14.055	13.652	EPSD	COSMIC	9.540	Down-regulation
Atypical_PIKK_ATM_ATM_ST	P37275	ZEB1	Q13315	ATM	S1100	A1098S	1098	Missense	proximal	-2	no	14.055	14.242	EPSD	COSMIC	9.540	Up-regulation
Atypical_PIKK_ATM_ATM_ST	P37275	ZEB1	Q13315	ATM	S1117	G1110A	1110	Missense	distal	-7	no	10.467	10.883	EPSD	COSMIC	9.540	Up-regulation
Atypical_PIKK_ATM_ATM_ST	P37275	ZEB1	Q13315	ATM	S1117	S1117P	1117	Missense	central	0	yes	10.467	0.000	EPSD	COSMIC	9.540	Loss
Atypical_PIKK_ATM_ATM_ST	P37275	ZEB1	Q13315	ATM	S1117	E1111K	1111	Missense	distal	-6	no	10.467	10.166	EPSD	COSMIC	9.540	Down-regulation
Atypical_PIKK_ATM_ATM_ST	P37275	ZEB1	Q13315	ATM	S1117	E1119G	1119	Missense	proximal	2	no	10.467	9.098	EPSD	COSMIC	9.540	Loss
Atypical_PIKK_ATM_ATM_ST	P11166	SLC2A1	Q13315	ATM	S113	S118F	118	Missense	distal	5	no	9.324	9.630	EPSD	COSMIC	9.540	Gain
Atypical_PIKK_ATM_ATM_ST	P11166	SLC2A1	Q13315	ATM	S473	F467L	467	Missense	distal	-6	no	14.050	14.293	EPSD	COSMIC	9.540	Up-regulation
Atypical_PIKK_ATM_ATM_ST	P11166	SLC2A1	Q13315	ATM	S473	R468W	468	Missense	distal	-5	no	14.050	14.215	EPSD	COSMIC	9.540	Up-regulation
Atypical_PIKK_ATM_ATM_ST	Q969R5	L3MBTL2	Q13315	ATM	S42	S39R	39	Missense	distal	-3	no	9.513	10.253	EPSD	COSMIC	9.540	Gain
Atypical_PIKK_ATM_ATM_ST	Q969R5	L3MBTL2	Q13315	ATM	S85	E91D	91	Missense	distal	6	no	9.703	9.656	EPSD	COSMIC	9.540	Down-regulation
Atypical_PIKK_ATM_ATM_ST	Q969R5	L3MBTL2	Q13315	ATM	T98	E91D	91	Missense	distal	-7	no	9.638	9.060	EPSD	COSMIC	9.540	Loss
Atypical_PIKK_ATM_ATM_ST	Q969R5	L3MBTL2	Q13315	ATM	T98	G97D	97	Missense	proximal	-1	no	9.638	9.775	EPSD	COSMIC	9.540	Up-regulation
Atypical_PIKK_ATM_ATM_ST	Q969R5	L3MBTL2	Q13315	ATM	S117	K123R	123	Missense	distal	6	no	9.893	9.896	EPSD	COSMIC	9.540	Up-regulation
Atypical_PIKK_ATM_ATM_ST	Q969R5	L3MBTL2	Q13315	ATM	S335	R339C	339	Missense	distal	4	no	13.059	13.386	PhosphoSitePlus	COSMIC	9.540	Up-regulation
Atypical_PIKK_ATM_ATM_ST	Q969R5	L3MBTL2	Q13315	ATM	S683	S689G	689	Missense	distal	6	no	9.759	9.741	EPSD	COSMIC	9.540	Down-regulation
Atypical_PIKK_ATM_ATM_ST	Q969R5	L3MBTL2	Q13315	ATM	S689	S689G	689	Missense	central	0	yes	12.191	0.000	EPSD	COSMIC	9.540	Loss
Atypical_PIKK_ATM_ATM_ST	Q969R5	L3MBTL2	Q13315	ATM	T703	I699V	699	Missense	distal	-4	no	9.580	9.303	EPSD	COSMIC	9.540	Loss
Atypical_PIKK_ATM_ATM_ST	Q9Y4E8	USP15	Q13315	ATM	S229	P227H	227	Missense	proximal	-2	no	9.671	9.480	EPSD	COSMIC	9.540	Loss
Atypical_PIKK_ATM_ATM_ST	Q9Y4E8	USP15	Q13315	ATM	S229	P230Q	230	Missense	proximal	1	no	9.671	14.473	EPSD	COSMIC	9.540	Up-regulation
Atypical_PIKK_ATM_ATM_ST	Q9Y4E8	USP15	Q13315	ATM	S229	S229F	229	Missense	central	0	yes	9.671	0.000	EPSD	COSMIC	9.540	Loss
Atypical_PIKK_ATM_ATM_ST	Q9Y4E8	USP15	Q13315	ATM	S277	E278Q	278	Missense	proximal	1	no	9.341	15.237	EPSD	COSMIC	9.540	Gain
Atypical_PIKK_ATM_ATM_ST	Q9Y4E8	USP15	Q13315	ATM	S355	A361D	361	Missense	distal	6	no	10.880	10.851	EPSD	COSMIC	9.540	Down-regulation
Atypical_PIKK_ATM_ATM_ST	Q9Y4E8	USP15	Q13315	ATM	S355	R360K	360	Missense	distal	5	no	10.880	10.718	EPSD	COSMIC	9.540	Down-regulation
Atypical_PIKK_ATM_ATM_ST	Q9Y4E8	USP15	Q13315	ATM	S355	M349T	349	Missense	distal	-6	no	10.880	11.056	EPSD	COSMIC	9.540	Up-regulation
Atypical_PIKK_ATM_ATM_ST	Q9Y4E8	USP15	Q13315	ATM	S355	W350C	350	Missense	distal	-5	no	10.880	10.731	EPSD	COSMIC	9.540	Down-regulation
Atypical_PIKK_ATM_ATM_ST	Q9Y4E8	USP15	Q13315	ATM	S355	W350L	350	Missense	distal	-5	no	10.880	10.661	EPSD	COSMIC	9.540	Down-regulation
Atypical_PIKK_ATM_ATM_ST	Q9Y4E8	USP15	Q13315	ATM	S355	V357I	357	Missense	proximal	2	no	10.880	11.087	EPSD	COSMIC	9.540	Up-regulation
Atypical_PIKK_ATM_ATM_ST	Q9Y4E8	USP15	Q13315	ATM	S579	H582N	582	Missense	distal	3	no	11.010	10.987	EPSD	COSMIC	9.540	Down-regulation
Atypical_PIKK_ATM_ATM_ST	Q9Y4E8	USP15	Q13315	ATM	S579	S586F	586	Missense	distal	7	no	11.010	11.070	EPSD	COSMIC	9.540	Up-regulation
Atypical_PIKK_ATM_ATM_ST	Q9Y4E8	USP15	Q13315	ATM	S579	R576K	576	Missense	distal	-3	no	11.010	10.178	EPSD	COSMIC	9.540	Down-regulation
Atypical_PIKK_ATM_ATM_ST	Q9Y4E8	USP15	Q13315	ATM	T602	R599Q	599	Missense	distal	-3	no	10.156	9.381	EPSD	COSMIC	9.540	Loss
Atypical_PIKK_ATM_ATM_ST	Q9Y4E8	USP15	Q13315	ATM	T624	S621F	621	Missense	distal	-3	no	8.640	9.712	EPSD	COSMIC	9.540	Gain
Atypical_PIKK_ATM_ATM_ST	Q9Y4E8	USP15	Q13315	ATM	S630	E628K	628	Missense	proximal	-2	no	10.181	9.605	EPSD	COSMIC	9.540	Down-regulation
Atypical_PIKK_ATM_ATM_ST	Q9Y4E8	USP15	Q13315	ATM	S630	Q637K	637	Missense	distal	7	no	10.181	10.193	EPSD	COSMIC	9.540	Up-regulation
Atypical_PIKK_ATM_ATM_ST	Q9Y4E8	USP15	Q13315	ATM	S678	D682A	682	Missense	distal	4	no	16.513	15.958	PhosphoSitePlus	COSMIC	9.540	Down-regulation
Atypical_PIKK_ATM_ATM_ST	Q9Y4E8	USP15	Q13315	ATM	S678	S678R	678	Missense	central	0	yes	16.513	0.000	PhosphoSitePlus	COSMIC	9.540	Loss
Atypical_PIKK_ATM_ATM_ST	Q9Y4E8	USP15	Q13315	ATM	S678	Q679L	679	Missense	proximal	1	no	16.513	10.157	PhosphoSitePlus	COSMIC	9.540	Down-regulation
Atypical_PIKK_ATM_ATM_ST	Q8IW19	APLF	Q13315	ATM	S144	S149N	149	Missense	distal	5	no	11.874	11.849	EPSD	COSMIC	9.540	Down-regulation
Atypical_PIKK_ATM_ATM_ST	Q8IW19	APLF	Q13315	ATM	S144	S149I	149	Missense	distal	5	no	11.874	12.083	EPSD	COSMIC	9.540	Up-regulation
Atypical_PIKK_ATM_ATM_ST	Q8IW19	APLF	Q13315	ATM	T155	S149N	149	Missense	distal	-6	no	12.830	12.715	EPSD	COSMIC	9.540	Down-regulation
Atypical_PIKK_ATM_ATM_ST	Q8IW19	APLF	Q13315	ATM	T155	S149I	149	Missense	distal	-6	no	12.830	12.429	EPSD	COSMIC	9.540	Down-regulation
Atypical_PIKK_ATM_ATM_ST	Q8IW19	APLF	Q13315	ATM	T155	S162C	162	Missense	distal	7	no	12.830	12.883	EPSD	COSMIC;GDSC;CCLE	9.540	Up-regulation
Atypical_PIKK_ATM_ATM_ST	Q9Y2K7	KDM2A	Q13315	ATM	S11	E4K	4	Missense	distal	-7	no	15.759	15.091	EPSD	COSMIC	9.540	Down-regulation
Atypical_PIKK_ATM_ATM_ST	Q9Y2K7	KDM2A	Q13315	ATM	S11	R15C	15	Missense	distal	4	no	15.759	16.086	EPSD	COSMIC	9.540	Up-regulation
Atypical_PIKK_ATM_ATM_ST	Q9Y2K7	KDM2A	Q13315	ATM	S11	G16C	16	Missense	distal	5	no	15.759	15.807	EPSD	COSMIC	9.540	Up-regulation
Atypical_PIKK_ATM_ATM_ST	Q9Y2K7	KDM2A	Q13315	ATM	S81	D82H	82	Missense	proximal	1	no	10.764	1.886	EPSD	COSMIC;CCLE	9.540	Loss
Atypical_PIKK_ATM_ATM_ST	Q9Y2K7	KDM2A	Q13315	ATM	S81	S81F	81	Missense	central	0	yes	10.764	0.000	EPSD	COSMIC	9.540	Loss
Atypical_PIKK_ATM_ATM_ST	Q9Y2K7	KDM2A	Q13315	ATM	S81	K79Q	79	Missense	proximal	-2	no	10.764	11.035	EPSD	COSMIC	9.540	Up-regulation
Atypical_PIKK_ATM_ATM_ST	Q9Y2K7	KDM2A	Q13315	ATM	S394	S387F	387	Missense	distal	-7	no	10.277	9.447	EPSD	COSMIC	9.540	Loss
Atypical_PIKK_ATM_ATM_ST	Q9Y2K7	KDM2A	Q13315	ATM	T526	R527Q	527	Missense	proximal	1	no	4.900	11.552	EPSD	COSMIC	9.540	Gain
Atypical_PIKK_ATM_ATM_ST	Q9Y2K7	KDM2A	Q13315	ATM	S558	A555V	555	Missense	distal	-3	no	9.253	10.117	EPSD	COSMIC	9.540	Gain
Atypical_PIKK_ATM_ATM_ST	Q9Y2K7	KDM2A	Q13315	ATM	T632	D634H	634	Missense	proximal	2	no	14.847	13.785	PhosphoSitePlus	COSMIC	9.540	Down-regulation
Atypical_PIKK_ATM_ATM_ST	Q9Y2K7	KDM2A	Q13315	ATM	S718	M722I	722	Missense	distal	4	no	9.564	9.966	EPSD	COSMIC	9.540	Up-regulation
Atypical_PIKK_ATM_ATM_ST	Q9Y2K7	KDM2A	Q13315	ATM	S718	S721F	721	Missense	distal	3	no	9.564	10.146	EPSD	COSMIC	9.540	Up-regulation
Atypical_PIKK_ATM_ATM_ST	Q9Y2K7	KDM2A	Q13315	ATM	S797	K791E	791	Missense	distal	-6	no	9.600	9.901	EPSD	COSMIC	9.540	Up-regulation
Atypical_PIKK_ATM_ATM_ST	Q9Y2K7	KDM2A	Q13315	ATM	S797	I794L	794	Missense	distal	-3	no	9.600	9.139	EPSD	COSMIC	9.540	Loss
Atypical_PIKK_ATM_ATM_ST	Q9Y2K7	KDM2A	Q13315	ATM	S797	G796R	796	Missense	proximal	-1	no	9.600	9.417	EPSD	COSMIC	9.540	Loss
Atypical_PIKK_ATM_ATM_ST	Q9Y2K7	KDM2A	Q13315	ATM	S797	R795Q	795	Missense	proximal	-2	no	9.600	9.919	EPSD	COSMIC	9.540	Up-regulation
Atypical_PIKK_ATM_ATM_ST	Q9Y2K7	KDM2A	Q13315	ATM	S832	L829F	829	Missense	distal	-3	no	8.808	9.671	EPSD	COSMIC	9.540	Gain
Atypical_PIKK_ATM_ATM_ST	Q9Y2K7	KDM2A	Q13315	ATM	S832	R834S	834	Missense	proximal	2	no	8.808	9.806	EPSD	COSMIC;GDSC;CCLE	9.540	Gain
Atypical_PIKK_ATM_ATM_ST	Q9Y2K7	KDM2A	Q13315	ATM	S869	E872G	872	Missense	distal	3	no	11.030	11.336	EPSD	COSMIC	9.540	Up-regulation
Atypical_PIKK_ATM_ATM_ST	Q9Y2K7	KDM2A	Q13315	ATM	S883	W884L	884	Missense	proximal	1	no	3.338	9.587	EPSD	COSMIC	9.540	Gain
Atypical_PIKK_ATM_ATM_ST	Q02535	ID3	Q13315	ATM	S65	V58D	58	Missense	distal	-7	no	14.211	14.470	PhosphoSitePlus	COSMIC	9.540	Up-regulation
Atypical_PIKK_ATM_ATM_ST	Q02535	ID3	Q13315	ATM	S65	E68D	68	Missense	distal	3	no	14.211	14.571	PhosphoSitePlus	COSMIC	9.540	Up-regulation
Atypical_PIKK_ATM_ATM_ST	Q02535	ID3	Q13315	ATM	S65	V67G	67	Missense	proximal	2	no	14.211	14.245	PhosphoSitePlus	COSMIC	9.540	Up-regulation
Atypical_PIKK_ATM_ATM_ST	Q02535	ID3	Q13315	ATM	S65	P59T	59	Missense	distal	-6	no	14.211	14.201	PhosphoSitePlus	COSMIC	9.540	Down-regulation
Atypical_PIKK_ATM_ATM_ST	Q02535	ID3	Q13315	ATM	S65	Q63R	63	Missense	proximal	-2	no	14.211	13.893	PhosphoSitePlus	COSMIC	9.540	Down-regulation
Atypical_PIKK_ATM_ATM_ST	Q02535	ID3	Q13315	ATM	S65	S65I	65	Missense	central	0	yes	14.211	0.000	PhosphoSitePlus	COSMIC	9.540	Loss
Atypical_PIKK_ATM_ATM_ST	Q02535	ID3	Q13315	ATM	S65	S65R	65	Missense	central	0	yes	14.211	0.000	PhosphoSitePlus	COSMIC	9.540	Loss
Atypical_PIKK_ATM_ATM_ST	Q02535	ID3	Q13315	ATM	S65	G61C	61	Missense	distal	-4	no	14.211	13.427	PhosphoSitePlus	COSMIC	9.540	Down-regulation
Atypical_PIKK_ATM_ATM_ST	Q02535	ID3	Q13315	ATM	S65	R72C	72	Missense	distal	7	no	14.211	14.229	PhosphoSitePlus	COSMIC	9.540	Up-regulation
Atypical_PIKK_ATM_ATM_ST	Q02535	ID3	Q13315	ATM	S65	L70P	70	Missense	distal	5	no	14.211	14.229	PhosphoSitePlus	COSMIC	9.540	Up-regulation
Atypical_PIKK_ATM_ATM_ST	P46379	BAG6	Q13315	ATM	S104	G103R	103	Missense	proximal	-1	no	10.760	10.577	EPSD	COSMIC	9.540	Down-regulation
Atypical_PIKK_ATM_ATM_ST	P46379	BAG6	Q13315	ATM	S181	R182Q	182	Missense	proximal	1	no	5.234	11.886	EPSD	COSMIC	9.540	Gain
Atypical_PIKK_ATM_ATM_ST	P46379	BAG6	Q13315	ATM	S200	P207L	207	Missense	distal	7	no	15.092	15.093	EPSD	COSMIC	9.540	Up-regulation
Atypical_PIKK_ATM_ATM_ST	P46379	BAG6	Q13315	ATM	S218	V214I	214	Missense	distal	-4	no	14.170	14.448	EPSD;PhosphoSitePlus	COSMIC	9.540	Up-regulation
Atypical_PIKK_ATM_ATM_ST	P46379	BAG6	Q13315	ATM	S697	S703L	703	Missense	distal	6	no	10.183	10.126	EPSD	COSMIC	9.540	Down-regulation
Atypical_PIKK_ATM_ATM_ST	P46379	BAG6	Q13315	ATM	S1081	D1088N	1088	Missense	distal	7	no	9.713	9.720	EPSD	COSMIC	9.540	Up-regulation
Atypical_PIKK_ATM_ATM_ST	P46379	BAG6	Q13315	ATM	S1081	R1077Q	1077	Missense	distal	-4	no	9.713	10.079	EPSD	COSMIC	9.540	Up-regulation
Atypical_PIKK_ATM_ATM_ST	P46379	BAG6	Q13315	ATM	S1117	P1122L	1122	Missense	distal	5	no	11.984	11.967	EPSD	COSMIC	9.540	Down-regulation
Atypical_PIKK_ATM_ATM_ST	Q9NUW8	TDP1	Q13315	ATM	S2	Q3H	3	Missense	proximal	1	no	11.635	-3.274	EPSD	COSMIC	9.540	Loss
Atypical_PIKK_ATM_ATM_ST	Q9NUW8	TDP1	Q13315	ATM	S81	S79C	79	Missense	proximal	-2	no	15.092	14.630	EPSD;PhosphoSitePlus	COSMIC	9.540	Down-regulation
Atypical_PIKK_ATM_ATM_ST	Q9NUW8	TDP1	Q13315	ATM	S365	F362L	362	Missense	distal	-3	no	18.601	17.739	PhosphoSitePlus;EPSD	COSMIC	9.540	Down-regulation
Atypical_PIKK_ATM_ATM_ST	Q9NUW8	TDP1	Q13315	ATM	S365	N369D	369	Missense	distal	4	no	18.601	18.682	PhosphoSitePlus;EPSD	COSMIC	9.540	Up-regulation
Atypical_PIKK_ATM_ATM_ST	Q9NUW8	TDP1	Q13315	ATM	S563	A561T	561	Missense	proximal	-2	no	17.540	17.640	EPSD;PhosphoSitePlus	COSMIC	9.540	Up-regulation
Atypical_PIKK_ATM_ATM_ST	Q9NUW8	TDP1	Q13315	ATM	S563	P566L	566	Missense	distal	3	no	17.540	17.670	EPSD;PhosphoSitePlus	COSMIC;GDSC;CCLE	9.540	Up-regulation
Atypical_PIKK_ATM_ATM_ST	Q14683	SMC1A	Q13315	ATM	S85	R92G	92	Missense	distal	7	no	10.883	10.889	EPSD	COSMIC	9.540	Up-regulation
Atypical_PIKK_ATM_ATM_ST	Q14683	SMC1A	Q13315	ATM	S85	A78T	78	Missense	distal	-7	no	10.883	10.898	EPSD	COSMIC	9.540	Up-regulation
Atypical_PIKK_ATM_ATM_ST	Q14683	SMC1A	Q13315	ATM	T182	T182A	182	Missense	central	0	yes	12.377	0.000	EPSD	COSMIC	9.540	Loss
Atypical_PIKK_ATM_ATM_ST	Q14683	SMC1A	Q13315	ATM	S358	R363T	363	Missense	distal	5	no	15.601	15.419	EPSD	COSMIC	9.540	Down-regulation
Atypical_PIKK_ATM_ATM_ST	Q14683	SMC1A	Q13315	ATM	S360	T366A	366	Missense	distal	6	no	15.422	15.438	EPSD	COSMIC	9.540	Up-regulation
Atypical_PIKK_ATM_ATM_ST	Q14683	SMC1A	Q13315	ATM	S360	R363T	363	Missense	distal	3	no	15.422	15.317	EPSD	COSMIC	9.540	Down-regulation
Atypical_PIKK_ATM_ATM_ST	Q14683	SMC1A	Q13315	ATM	S448	K453M	453	Missense	distal	5	no	10.066	10.247	EPSD	COSMIC	9.540	Up-regulation
Atypical_PIKK_ATM_ATM_ST	Q14683	SMC1A	Q13315	ATM	S448	L455P	455	Missense	distal	7	no	10.066	10.065	EPSD	COSMIC	9.540	Down-regulation
Atypical_PIKK_ATM_ATM_ST	Q14683	SMC1A	Q13315	ATM	S448	S448F	448	Missense	central	0	yes	10.066	0.000	EPSD	COSMIC	9.540	Loss
Atypical_PIKK_ATM_ATM_ST	Q14683	SMC1A	Q13315	ATM	S703	S703F	703	Missense	central	0	yes	15.804	0.000	EPSD	COSMIC	9.540	Loss
Atypical_PIKK_ATM_ATM_ST	Q14683	SMC1A	Q13315	ATM	S703	G707V	707	Missense	distal	4	no	15.804	15.981	EPSD	COSMIC	9.540	Up-regulation
Atypical_PIKK_ATM_ATM_ST	Q14683	SMC1A	Q13315	ATM	S703	A705V	705	Missense	proximal	2	no	15.804	15.495	EPSD	COSMIC;GDSC;CCLE	9.540	Down-regulation
Atypical_PIKK_ATM_ATM_ST	Q14683	SMC1A	Q13315	ATM	S703	R699H	699	Missense	distal	-4	no	15.804	15.935	EPSD	COSMIC	9.540	Up-regulation
Atypical_PIKK_ATM_ATM_ST	Q14683	SMC1A	Q13315	ATM	S715	E720K	720	Missense	distal	5	no	13.230	13.405	EPSD	COSMIC	9.540	Up-regulation
Atypical_PIKK_ATM_ATM_ST	Q14683	SMC1A	Q13315	ATM	S951	S957F	957	Missense	distal	6	no	12.066	11.990	EPSD	COSMIC	9.540	Down-regulation
Atypical_PIKK_ATM_ATM_ST	Q14683	SMC1A	Q13315	ATM	S951	D949Y	949	Missense	proximal	-2	no	12.066	12.195	EPSD	COSMIC	9.540	Up-regulation
Atypical_PIKK_ATM_ATM_ST	Q14683	SMC1A	Q13315	ATM	S957	S957F	957	Missense	central	0	yes	14.210	0.000	PhosphoSitePlus;EPSD	COSMIC	9.540	Loss
Atypical_PIKK_ATM_ATM_ST	Q14683	SMC1A	Q13315	ATM	S964	S957F	957	Missense	distal	-7	no	10.957	10.127	EPSD	COSMIC	9.540	Down-regulation
Atypical_PIKK_ATM_ATM_ST	Q14683	SMC1A	Q13315	ATM	S964	S971G	971	Missense	distal	7	no	10.957	10.998	EPSD	COSMIC	9.540	Up-regulation
Atypical_PIKK_ATM_ATM_ST	Q14683	SMC1A	Q13315	ATM	S966	S971G	971	Missense	distal	5	no	14.373	14.551	EPSD;PhosphoSitePlus	COSMIC	9.540	Up-regulation
Atypical_PIKK_ATM_ATM_ST	P54132	BLM	Q13315	ATM	S28	K29E	29	Missense	proximal	1	no	8.895	9.847	EPSD	COSMIC	9.540	Gain
Atypical_PIKK_ATM_ATM_ST	P54132	BLM	Q13315	ATM	S74	S72F	72	Missense	proximal	-2	no	13.187	12.287	EPSD	COSMIC	9.540	Down-regulation
Atypical_PIKK_ATM_ATM_ST	P54132	BLM	Q13315	ATM	T99	G102D	102	Missense	distal	3	no	13.631	13.683	EPSD;PhosphoSitePlus	COSMIC	9.540	Up-regulation
Atypical_PIKK_ATM_ATM_ST	P54132	BLM	Q13315	ATM	T99	G96V	96	Missense	distal	-3	no	13.631	13.771	EPSD;PhosphoSitePlus	COSMIC	9.540	Up-regulation
Atypical_PIKK_ATM_ATM_ST	P54132	BLM	Q13315	ATM	T99	R101T	101	Missense	proximal	2	no	13.631	14.366	EPSD;PhosphoSitePlus	COSMIC	9.540	Up-regulation
Atypical_PIKK_ATM_ATM_ST	P54132	BLM	Q13315	ATM	T99	S104L	104	Missense	distal	5	no	13.631	13.795	EPSD;PhosphoSitePlus	COSMIC	9.540	Up-regulation
Atypical_PIKK_ATM_ATM_ST	P54132	BLM	Q13315	ATM	T99	N92D	92	Missense	distal	-7	no	13.631	13.595	EPSD;PhosphoSitePlus	COSMIC;GDSC	9.540	Down-regulation
Atypical_PIKK_ATM_ATM_ST	P54132	BLM	Q13315	ATM	T122	V118I	118	Missense	distal	-4	no	13.098	13.376	PhosphoSitePlus;EPSD	COSMIC	9.540	Up-regulation
Atypical_PIKK_ATM_ATM_ST	P54132	BLM	Q13315	ATM	T122	P126S	126	Missense	distal	4	no	13.098	12.976	PhosphoSitePlus;EPSD	COSMIC	9.540	Down-regulation
Atypical_PIKK_ATM_ATM_ST	P54132	BLM	Q13315	ATM	T122	P115L	115	Missense	distal	-7	no	13.098	12.747	PhosphoSitePlus;EPSD	COSMIC	9.540	Down-regulation
Atypical_PIKK_ATM_ATM_ST	P54132	BLM	Q13315	ATM	T122	E117K	117	Missense	distal	-5	no	13.098	13.180	PhosphoSitePlus;EPSD	COSMIC	9.540	Up-regulation
Atypical_PIKK_ATM_ATM_ST	P54132	BLM	Q13315	ATM	S144	S147F	147	Missense	distal	3	no	11.497	12.079	EPSD	COSMIC	9.540	Up-regulation
Atypical_PIKK_ATM_ATM_ST	P54132	BLM	Q13315	ATM	S144	S144L	144	Missense	central	0	yes	11.497	0.000	EPSD	COSMIC	9.540	Loss
Atypical_PIKK_ATM_ATM_ST	P54132	BLM	Q13315	ATM	S144	T150I	150	Missense	distal	6	no	11.497	11.466	EPSD	COSMIC	9.540	Down-regulation
Atypical_PIKK_ATM_ATM_ST	P54132	BLM	Q13315	ATM	S144	I151M	151	Missense	distal	7	no	11.497	11.499	EPSD	COSMIC	9.540	Up-regulation
Atypical_PIKK_ATM_ATM_ST	P54132	BLM	Q13315	ATM	S166	E164K	164	Missense	proximal	-2	no	9.902	9.327	EPSD	COSMIC	9.540	Loss
Atypical_PIKK_ATM_ATM_ST	P54132	BLM	Q13315	ATM	S166	S168L	168	Missense	proximal	2	no	9.902	8.659	EPSD	COSMIC	9.540	Loss
Atypical_PIKK_ATM_ATM_ST	P54132	BLM	Q13315	ATM	S166	S163Y	163	Missense	distal	-3	no	9.902	10.035	EPSD	COSMIC	9.540	Up-regulation
Atypical_PIKK_ATM_ATM_ST	P54132	BLM	Q13315	ATM	T283	H281P	281	Missense	proximal	-2	no	9.362	9.552	EPSD	COSMIC	9.540	Gain
Atypical_PIKK_ATM_ATM_ST	P54132	BLM	Q13315	ATM	S314	S315Y	315	Missense	proximal	1	no	5.098	11.159	EPSD	COSMIC	9.540	Gain
Atypical_PIKK_ATM_ATM_ST	P54132	BLM	Q13315	ATM	S367	H374Y	374	Missense	distal	7	no	9.618	9.623	EPSD	COSMIC	9.540	Up-regulation
Atypical_PIKK_ATM_ATM_ST	P54132	BLM	Q13315	ATM	S367	I366T	366	Missense	proximal	-1	no	9.618	9.848	EPSD	COSMIC;GDSC	9.540	Up-regulation
Atypical_PIKK_ATM_ATM_ST	P54132	BLM	Q13315	ATM	S367	C361Y	361	Missense	distal	-6	no	9.618	9.748	EPSD	COSMIC;CCLE	9.540	Up-regulation
Atypical_PIKK_ATM_ATM_ST	P54132	BLM	Q13315	ATM	S367	A363S	363	Missense	distal	-4	no	9.618	10.127	EPSD	COSMIC	9.540	Up-regulation
Atypical_PIKK_ATM_ATM_ST	P54132	BLM	Q13315	ATM	S367	H374D	374	Missense	distal	7	no	9.618	9.597	EPSD	COSMIC	9.540	Down-regulation
Atypical_PIKK_ATM_ATM_ST	P54132	BLM	Q13315	ATM	S419	S426L	426	Missense	distal	7	no	11.145	11.164	EPSD	COSMIC	9.540	Up-regulation
Atypical_PIKK_ATM_ATM_ST	P54132	BLM	Q13315	ATM	S419	N417S	417	Missense	proximal	-2	no	11.145	11.325	EPSD	COSMIC	9.540	Up-regulation
Atypical_PIKK_ATM_ATM_ST	P54132	BLM	Q13315	ATM	S419	D415Y	415	Missense	distal	-4	no	11.145	10.048	EPSD	COSMIC	9.540	Down-regulation
Atypical_PIKK_ATM_ATM_ST	P54132	BLM	Q13315	ATM	S426	S426L	426	Missense	central	0	yes	11.389	0.000	EPSD	COSMIC	9.540	Loss
Atypical_PIKK_ATM_ATM_ST	P54132	BLM	Q13315	ATM	S550	Y551C	551	Missense	proximal	1	no	12.539	6.044	EPSD	COSMIC	9.540	Loss
Atypical_PIKK_ATM_ATM_ST	P54132	BLM	Q13315	ATM	S550	Q548K	548	Missense	proximal	-2	no	12.539	12.268	EPSD	COSMIC	9.540	Down-regulation
Atypical_PIKK_ATM_ATM_ST	P54132	BLM	Q13315	ATM	S646	S646G	646	Missense	central	0	yes	10.302	0.000	EPSD	COSMIC	9.540	Loss
Atypical_PIKK_ATM_ATM_ST	P54132	BLM	Q13315	ATM	S1138	R1139Q	1139	Missense	proximal	1	no	6.745	13.396	EPSD	COSMIC;CCLE	9.540	Gain
Atypical_PIKK_ATM_ATM_ST	P54132	BLM	Q13315	ATM	S1290	Q1283H	1283	Missense	distal	-7	no	10.693	10.579	EPSD	COSMIC	9.540	Down-regulation
Atypical_PIKK_ATM_ATM_ST	P54132	BLM	Q13315	ATM	S1290	S1290L	1290	Missense	central	0	yes	10.693	0.000	EPSD	COSMIC	9.540	Loss
Atypical_PIKK_ATM_ATM_ST	Q14190	SIM2	Q13315	ATM	S471	Q469P	469	Missense	proximal	-2	no	9.969	9.857	EPSD	COSMIC	9.540	Down-regulation
Atypical_PIKK_ATM_ATM_ST	P54274	TERF1	Q13315	ATM	S114	I108V	108	Missense	distal	-6	no	9.744	9.888	EPSD	COSMIC;GDSC;CCLE	9.540	Up-regulation
Atypical_PIKK_ATM_ATM_ST	P54274	TERF1	Q13315	ATM	S114	R121K	121	Missense	distal	7	no	9.744	9.732	EPSD	COSMIC	9.540	Down-regulation
Atypical_PIKK_ATM_ATM_ST	P54274	TERF1	Q13315	ATM	T330	N336H	336	Missense	distal	6	no	11.179	11.156	EPSD	COSMIC;GDSC;CCLE	9.540	Down-regulation
Atypical_PIKK_ATM_ATM_ST	P54274	TERF1	Q13315	ATM	T330	Q331K	331	Missense	proximal	1	no	11.179	4.331	EPSD	COSMIC	9.540	Loss
Atypical_PIKK_ATM_ATM_ST	P54274	TERF1	Q13315	ATM	S367	P363A	363	Missense	distal	-4	no	16.705	16.865	PhosphoSitePlus;EPSD	COSMIC	9.540	Up-regulation
Atypical_PIKK_ATM_ATM_ST	P54274	TERF1	Q13315	ATM	S367	P372H	372	Missense	distal	5	no	16.705	16.663	PhosphoSitePlus;EPSD	COSMIC	9.540	Down-regulation
Atypical_PIKK_ATM_ATM_ST	P54274	TERF1	Q13315	ATM	S404	E400G	400	Missense	distal	-4	no	10.048	8.982	EPSD	COSMIC;GDSC;CCLE	9.540	Loss
Atypical_PIKK_ATM_ATM_ST	P54274	TERF1	Q13315	ATM	S404	L408F	408	Missense	distal	4	no	10.048	10.535	EPSD	COSMIC	9.540	Up-regulation
Atypical_PIKK_ATM_ATM_ST	P54274	TERF1	Q13315	ATM	S435	S434C	434	Missense	proximal	-1	no	9.678	9.478	EPSD	COSMIC	9.540	Loss
Atypical_PIKK_ATM_ATM_ST	P54274	TERF1	Q13315	ATM	S435	I433N	433	Missense	proximal	-2	no	9.678	10.188	EPSD	COSMIC	9.540	Up-regulation
Atypical_PIKK_ATM_ATM_ST	P54274	TERF1	Q13315	ATM	S437	S434C	434	Missense	distal	-3	no	12.023	12.191	EPSD	COSMIC	9.540	Up-regulation
Atypical_PIKK_ATM_ATM_ST	P54274	TERF1	Q13315	ATM	S437	I433N	433	Missense	distal	-4	no	12.023	11.807	EPSD	COSMIC	9.540	Down-regulation
Atypical_PIKK_ATM_ATM_ST	Q14161	GIT2	Q13315	ATM	S46	G42W	42	Missense	distal	-4	no	12.860	12.362	EPSD	COSMIC	9.540	Down-regulation
Atypical_PIKK_ATM_ATM_ST	Q14161	GIT2	Q13315	ATM	T195	S199N	199	Missense	distal	4	no	13.965	14.092	EPSD;PhosphoSitePlus	COSMIC;GDSC;CCLE	9.540	Up-regulation
Atypical_PIKK_ATM_ATM_ST	Q14161	GIT2	Q13315	ATM	T195	Q196R	196	Missense	proximal	1	no	13.965	7.313	EPSD;PhosphoSitePlus	COSMIC	9.540	Loss
Atypical_PIKK_ATM_ATM_ST	Q14161	GIT2	Q13315	ATM	T195	V188I	188	Missense	distal	-7	no	13.965	13.781	EPSD;PhosphoSitePlus	COSMIC	9.540	Down-regulation
Atypical_PIKK_ATM_ATM_ST	Q14161	GIT2	Q13315	ATM	S384	D391N	391	Missense	distal	7	no	14.262	14.269	PhosphoSitePlus;EPSD	COSMIC	9.540	Up-regulation
Atypical_PIKK_ATM_ATM_ST	Q14161	GIT2	Q13315	ATM	S415	R412W	412	Missense	distal	-3	no	12.027	11.598	EPSD	COSMIC;GDSC	9.540	Down-regulation
Atypical_PIKK_ATM_ATM_ST	Q14161	GIT2	Q13315	ATM	S415	D419H	419	Missense	distal	4	no	12.027	11.937	EPSD	COSMIC	9.540	Down-regulation
Atypical_PIKK_ATM_ATM_ST	Q14161	GIT2	Q13315	ATM	S590	N597I	597	Missense	distal	7	no	10.566	10.582	EPSD	COSMIC	9.540	Up-regulation
Atypical_PIKK_ATM_ATM_ST	Q14161	GIT2	Q13315	ATM	S634	E641K	641	Missense	distal	7	no	10.775	10.802	EPSD	COSMIC	9.540	Up-regulation
Atypical_PIKK_ATM_ATM_ST	Q14161	GIT2	Q13315	ATM	S634	P633Q	633	Missense	proximal	-1	no	10.775	11.001	EPSD	COSMIC	9.540	Up-regulation
Atypical_PIKK_ATM_ATM_ST	Q14161	GIT2	Q13315	ATM	S634	P638L	638	Missense	distal	4	no	10.775	10.994	EPSD	COSMIC	9.540	Up-regulation
Atypical_PIKK_ATM_ATM_ST	Q14161	GIT2	Q13315	ATM	S634	P638S	638	Missense	distal	4	no	10.775	10.653	EPSD	COSMIC	9.540	Down-regulation
Atypical_PIKK_ATM_ATM_ST	Q14161	GIT2	Q13315	ATM	S724	V728I	728	Missense	distal	4	no	10.205	10.562	EPSD	COSMIC	9.540	Up-regulation
Atypical_PIKK_ATM_ATM_ST	Q14161	GIT2	Q13315	ATM	S724	G720V	720	Missense	distal	-4	no	10.205	10.004	EPSD	COSMIC	9.540	Down-regulation
Atypical_PIKK_ATM_ATM_ST	Q14161	GIT2	Q13315	ATM	T732	V728I	728	Missense	distal	-4	no	11.112	11.390	EPSD	COSMIC	9.540	Up-regulation
Atypical_PIKK_ATM_ATM_ST	Q5XUX0	FBXO31	Q13315	ATM	S400	R394Q	394	Missense	distal	-6	no	14.920	15.064	EPSD	COSMIC	9.540	Up-regulation
Atypical_PIKK_ATM_ATM_ST	Q5XUX0	FBXO31	Q13315	ATM	S400	P404L	404	Missense	distal	4	no	14.920	15.139	EPSD	COSMIC;GDSC;CCLE	9.540	Up-regulation
Atypical_PIKK_ATM_ATM_ST	Q5XUX0	FBXO31	Q13315	ATM	S400	P404S	404	Missense	distal	4	no	14.920	14.798	EPSD	COSMIC	9.540	Down-regulation
Atypical_PIKK_ATM_ATM_ST	Q5XUX0	FBXO31	Q13315	ATM	S400	A405S	405	Missense	distal	5	no	14.920	14.873	EPSD	COSMIC	9.540	Down-regulation
Atypical_PIKK_ATM_ATM_ST	Q5XUX0	FBXO31	Q13315	ATM	S403	P404L	404	Missense	proximal	1	no	11.239	9.684	EPSD	COSMIC;GDSC;CCLE	9.540	Down-regulation
Atypical_PIKK_ATM_ATM_ST	Q5XUX0	FBXO31	Q13315	ATM	S403	R398G	398	Missense	distal	-5	no	11.239	11.218	EPSD	COSMIC	9.540	Down-regulation
Atypical_PIKK_ATM_ATM_ST	Q5XUX0	FBXO31	Q13315	ATM	S403	P404S	404	Missense	proximal	1	no	11.239	4.264	EPSD	COSMIC	9.540	Loss
Atypical_PIKK_ATM_ATM_ST	Q5XUX0	FBXO31	Q13315	ATM	S403	A405S	405	Missense	proximal	2	no	11.239	11.822	EPSD	COSMIC	9.540	Up-regulation
Atypical_PIKK_ATM_ATM_ST	Q92905	COPS5	Q13315	ATM	S276	S270F	270	Missense	distal	-6	no	10.226	9.695	EPSD	COSMIC	9.540	Down-regulation
Atypical_PIKK_ATM_ATM_ST	Q92905	COPS5	Q13315	ATM	S276	A278T	278	Missense	proximal	2	no	10.226	10.547	EPSD	COSMIC	9.540	Up-regulation
Atypical_PIKK_ATM_ATM_ST	Q92905	COPS5	Q13315	ATM	S276	A278S	278	Missense	proximal	2	no	10.226	10.809	EPSD	COSMIC;GDSC;CCLE	9.540	Up-regulation
Atypical_PIKK_ATM_ATM_ST	Q92905	COPS5	Q13315	ATM	S276	Q275H	275	Missense	proximal	-1	no	10.226	10.089	EPSD	COSMIC	9.540	Down-regulation
Atypical_PIKK_ATM_ATM_ST	Q8WVD3	RNF138	Q13315	ATM	S124	P119A	119	Missense	distal	-5	no	14.483	14.472	PhosphoSitePlus	COSMIC	9.540	Down-regulation
Atypical_PIKK_ATM_ATM_ST	Q8WVD3	RNF138	Q13315	ATM	S124	S131C	131	Missense	distal	7	no	14.483	14.535	PhosphoSitePlus	COSMIC	9.540	Up-regulation
Atypical_PIKK_ATM_ATM_ST	Q8WVD3	RNF138	Q13315	ATM	S124	G129E	129	Missense	distal	5	no	14.483	14.134	PhosphoSitePlus	COSMIC	9.540	Down-regulation
Atypical_PIKK_ATM_ATM_ST	Q8WVD3	RNF138	Q13315	ATM	S124	D126N	126	Missense	proximal	2	no	14.483	13.461	PhosphoSitePlus	COSMIC	9.540	Down-regulation
Atypical_PIKK_ATM_ATM_ST	P15336	ATF2	Q13315	ATM	S112	M107I	107	Missense	distal	-5	no	10.016	10.046	EPSD	COSMIC;GDSC;CCLE	9.540	Up-regulation
Atypical_PIKK_ATM_ATM_ST	P15336	ATF2	Q13315	ATM	S112	K105T	105	Missense	distal	-7	no	10.016	10.247	EPSD	COSMIC;GDSC;CCLE	9.540	Up-regulation
Atypical_PIKK_ATM_ATM_ST	P15336	ATF2	Q13315	ATM	S112	K106R	106	Missense	distal	-6	no	10.016	9.949	EPSD	COSMIC	9.540	Down-regulation
Atypical_PIKK_ATM_ATM_ST	P15336	ATF2	Q13315	ATM	S112	D110E	110	Missense	proximal	-2	no	10.016	10.495	EPSD	COSMIC	9.540	Up-regulation
Atypical_PIKK_ATM_ATM_ST	P15336	ATF2	Q13315	ATM	T283	P287S	287	Missense	distal	4	no	11.837	11.714	EPSD	COSMIC	9.540	Down-regulation
Atypical_PIKK_ATM_ATM_ST	P15336	ATF2	Q13315	ATM	T305	T305I	305	Missense	central	0	yes	9.756	0.000	EPSD	COSMIC	9.540	Loss
Atypical_PIKK_ATM_ATM_ST	P15336	ATF2	Q13315	ATM	T305	R311Q	311	Missense	distal	6	no	9.756	9.752	EPSD	COSMIC;GDSC;CCLE	9.540	Down-regulation
Atypical_PIKK_ATM_ATM_ST	P15336	ATF2	Q13315	ATM	T305	G299D	299	Missense	distal	-6	no	9.756	9.931	EPSD	COSMIC	9.540	Up-regulation
Atypical_PIKK_ATM_ATM_ST	P15336	ATF2	Q13315	ATM	S307	T305I	305	Missense	proximal	-2	no	10.402	9.800	EPSD	COSMIC	9.540	Down-regulation
Atypical_PIKK_ATM_ATM_ST	P15336	ATF2	Q13315	ATM	S307	R311Q	311	Missense	distal	4	no	10.402	10.253	EPSD	COSMIC;GDSC;CCLE	9.540	Down-regulation
Atypical_PIKK_ATM_ATM_ST	P15336	ATF2	Q13315	ATM	S310	R311Q	311	Missense	proximal	1	no	6.615	13.266	EPSD	COSMIC;GDSC;CCLE	9.540	Gain
Atypical_PIKK_ATM_ATM_ST	P15336	ATF2	Q13315	ATM	S328	P326L	326	Missense	proximal	-2	no	10.429	10.276	EPSD	COSMIC;GDSC	9.540	Down-regulation
Atypical_PIKK_ATM_ATM_ST	P15336	ATF2	Q13315	ATM	S328	P326T	326	Missense	proximal	-2	no	10.429	10.578	EPSD	COSMIC	9.540	Up-regulation
Atypical_PIKK_ATM_ATM_ST	P15336	ATF2	Q13315	ATM	S328	Q335H	335	Missense	distal	7	no	10.429	10.448	EPSD	COSMIC	9.540	Up-regulation
Atypical_PIKK_ATM_ATM_ST	P15336	ATF2	Q13315	ATM	S328	P334S	334	Missense	distal	6	no	10.429	10.440	EPSD	COSMIC	9.540	Up-regulation
Atypical_PIKK_ATM_ATM_ST	P15336	ATF2	Q13315	ATM	S328	H331Y	331	Missense	distal	3	no	10.429	10.448	EPSD	COSMIC	9.540	Up-regulation
Atypical_PIKK_ATM_ATM_ST	P15336	ATF2	Q13315	ATM	T336	Q337K	337	Missense	proximal	1	no	12.972	6.123	EPSD	COSMIC	9.540	Loss
Atypical_PIKK_ATM_ATM_ST	P15336	ATF2	Q13315	ATM	T336	Q335H	335	Missense	proximal	-1	no	12.972	12.834	EPSD	COSMIC	9.540	Down-regulation
Atypical_PIKK_ATM_ATM_ST	P15336	ATF2	Q13315	ATM	T336	R343L	343	Missense	distal	7	no	12.972	12.956	EPSD	COSMIC	9.540	Down-regulation
Atypical_PIKK_ATM_ATM_ST	P15336	ATF2	Q13315	ATM	T336	P334S	334	Missense	proximal	-2	no	12.972	13.208	EPSD	COSMIC	9.540	Up-regulation
Atypical_PIKK_ATM_ATM_ST	P15336	ATF2	Q13315	ATM	T336	H331Y	331	Missense	distal	-5	no	12.972	12.947	EPSD	COSMIC	9.540	Down-regulation
Atypical_PIKK_ATM_ATM_ST	P15336	ATF2	Q13315	ATM	T336	R343Q	343	Missense	distal	7	no	12.972	12.947	EPSD	COSMIC	9.540	Down-regulation
Atypical_PIKK_ATM_ATM_ST	P15336	ATF2	Q13315	ATM	S438	S442L	442	Missense	distal	4	no	10.118	10.460	EPSD	COSMIC	9.540	Up-regulation
Atypical_PIKK_ATM_ATM_ST	P15336	ATF2	Q13315	ATM	S438	P444L	444	Missense	distal	6	no	10.118	10.073	EPSD	COSMIC	9.540	Down-regulation
Atypical_PIKK_ATM_ATM_ST	P15336	ATF2	Q13315	ATM	S438	P444T	444	Missense	distal	6	no	10.118	10.120	EPSD	COSMIC	9.540	Up-regulation
Atypical_PIKK_ATM_ATM_ST	P15336	ATF2	Q13315	ATM	S438	S437G	437	Missense	proximal	-1	no	10.118	9.927	EPSD	COSMIC	9.540	Down-regulation
Atypical_PIKK_ATM_ATM_ST	P15336	ATF2	Q13315	ATM	S438	S442P	442	Missense	distal	4	no	10.118	10.241	EPSD	COSMIC	9.540	Up-regulation
Atypical_PIKK_ATM_ATM_ST	P15336	ATF2	Q13315	ATM	S438	P444Q	444	Missense	distal	6	no	10.118	10.107	EPSD	COSMIC	9.540	Down-regulation
Atypical_PIKK_ATM_ATM_ST	P15336	ATF2	Q13315	ATM	S438	A432S	432	Missense	distal	-6	no	10.118	10.139	EPSD	COSMIC	9.540	Up-regulation
Atypical_PIKK_ATM_ATM_ST	P15336	ATF2	Q13315	ATM	S438	S437T	437	Missense	proximal	-1	no	10.118	10.129	EPSD	COSMIC	9.540	Up-regulation
Atypical_PIKK_ATM_ATM_ST	P15336	ATF2	Q13315	ATM	S446	P444T	444	Missense	proximal	-2	no	9.523	9.671	EPSD	COSMIC	9.540	Gain
Atypical_PIKK_ATM_ATM_ST	P15336	ATF2	Q13315	ATM	S446	P444Q	444	Missense	proximal	-2	no	9.523	9.635	EPSD	COSMIC	9.540	Gain
Atypical_PIKK_ATM_ATM_ST	P15336	ATF2	Q13315	ATM	S490	V493I	493	Missense	distal	3	no	15.398	15.556	PhosphoSitePlus;EPSD	COSMIC	9.540	Up-regulation
Atypical_PIKK_ATM_ATM_ST	P15336	ATF2	Q13315	ATM	S490	Q483K	483	Missense	distal	-7	no	15.398	15.285	PhosphoSitePlus;EPSD	COSMIC	9.540	Down-regulation
Atypical_PIKK_ATM_ATM_ST	P15336	ATF2	Q13315	ATM	S498	V493I	493	Missense	distal	-5	no	14.814	14.816	EPSD;PhosphoSitePlus	COSMIC	9.540	Up-regulation
Atypical_PIKK_ATM_ATM_ST	P15336	ATF2	Q13315	ATM	S498	Q501K	501	Missense	distal	3	no	14.814	14.844	EPSD;PhosphoSitePlus	COSMIC	9.540	Up-regulation
Atypical_PIKK_ATM_ATM_ST	P15336	ATF2	Q13315	ATM	S500	V493I	493	Missense	distal	-7	no	14.499	14.315	EPSD	COSMIC	9.540	Down-regulation
Atypical_PIKK_ATM_ATM_ST	P15336	ATF2	Q13315	ATM	S500	Q501K	501	Missense	proximal	1	no	14.499	7.651	EPSD	COSMIC	9.540	Loss
Atypical_PIKK_ATM_ATM_ST	P15336	ATF2	Q13315	ATM	S503	Q501K	501	Missense	proximal	-2	no	11.977	11.706	EPSD	COSMIC	9.540	Down-regulation
Atypical_PIKK_ATM_ATM_ST	Q14676	MDC1	Q13315	ATM	T17	E18Q	18	Missense	proximal	1	no	8.252	14.148	EPSD	COSMIC	9.540	Gain
Atypical_PIKK_ATM_ATM_ST	Q14676	MDC1	Q13315	ATM	S21	E18Q	18	Missense	distal	-3	no	11.922	12.046	EPSD	COSMIC	9.540	Up-regulation
Atypical_PIKK_ATM_ATM_ST	Q14676	MDC1	Q13315	ATM	S23	E18Q	18	Missense	distal	-5	no	11.007	11.039	EPSD	COSMIC	9.540	Up-regulation
Atypical_PIKK_ATM_ATM_ST	Q14676	MDC1	Q13315	ATM	T98	P103L	103	Missense	distal	5	no	13.758	13.741	EPSD;PhosphoSitePlus	COSMIC	9.540	Down-regulation
Atypical_PIKK_ATM_ATM_ST	Q14676	MDC1	Q13315	ATM	T98	P104S	104	Missense	distal	6	no	13.758	13.769	EPSD;PhosphoSitePlus	COSMIC	9.540	Up-regulation
Atypical_PIKK_ATM_ATM_ST	Q14676	MDC1	Q13315	ATM	T98	P104L	104	Missense	distal	6	no	13.758	13.713	EPSD;PhosphoSitePlus	COSMIC	9.540	Down-regulation
Atypical_PIKK_ATM_ATM_ST	Q14676	MDC1	Q13315	ATM	S112	H113P	113	Missense	proximal	1	no	1.879	11.986	EPSD	COSMIC	9.540	Gain
Atypical_PIKK_ATM_ATM_ST	Q14676	MDC1	Q13315	ATM	S136	S141C	141	Missense	distal	5	no	9.455	9.682	EPSD	COSMIC	9.540	Gain
Atypical_PIKK_ATM_ATM_ST	Q14676	MDC1	Q13315	ATM	S292	L289V	289	Missense	distal	-3	no	14.824	15.033	EPSD	COSMIC	9.540	Up-regulation
Atypical_PIKK_ATM_ATM_ST	Q14676	MDC1	Q13315	ATM	S292	P295S	295	Missense	distal	3	no	14.824	14.672	EPSD	COSMIC	9.540	Down-regulation
Atypical_PIKK_ATM_ATM_ST	Q14676	MDC1	Q13315	ATM	S292	P295L	295	Missense	distal	3	no	14.824	14.954	EPSD	COSMIC	9.540	Up-regulation
Atypical_PIKK_ATM_ATM_ST	Q14676	MDC1	Q13315	ATM	S329	A333V	333	Missense	distal	4	no	8.974	9.627	EPSD	COSMIC	9.540	Gain
Atypical_PIKK_ATM_ATM_ST	Q14676	MDC1	Q13315	ATM	T341	V343I	343	Missense	proximal	2	no	9.811	10.018	EPSD	COSMIC	9.540	Up-regulation
Atypical_PIKK_ATM_ATM_ST	Q14676	MDC1	Q13315	ATM	T341	P346A	346	Missense	distal	5	no	9.811	9.677	EPSD	COSMIC	9.540	Down-regulation
Atypical_PIKK_ATM_ATM_ST	Q14676	MDC1	Q13315	ATM	T341	P342S	342	Missense	proximal	1	no	9.811	2.836	EPSD	COSMIC	9.540	Loss
Atypical_PIKK_ATM_ATM_ST	Q14676	MDC1	Q13315	ATM	S372	Q370R	370	Missense	proximal	-2	no	13.561	13.243	EPSD	COSMIC	9.540	Down-regulation
Atypical_PIKK_ATM_ATM_ST	Q14676	MDC1	Q13315	ATM	S372	Q373L	373	Missense	proximal	1	no	13.561	7.205	EPSD	COSMIC	9.540	Loss
Atypical_PIKK_ATM_ATM_ST	Q14676	MDC1	Q13315	ATM	S394	A388V	388	Missense	distal	-6	no	15.205	14.969	EPSD	COSMIC	9.540	Down-regulation
Atypical_PIKK_ATM_ATM_ST	Q14676	MDC1	Q13315	ATM	S394	E392K	392	Missense	proximal	-2	no	15.205	14.629	EPSD	COSMIC	9.540	Down-regulation
Atypical_PIKK_ATM_ATM_ST	Q14676	MDC1	Q13315	ATM	S422	H418Q	418	Missense	distal	-4	no	13.385	13.620	EPSD	COSMIC	9.540	Up-regulation
Atypical_PIKK_ATM_ATM_ST	Q14676	MDC1	Q13315	ATM	S422	L419Q	419	Missense	distal	-3	no	13.385	13.141	EPSD	COSMIC	9.540	Down-regulation
Atypical_PIKK_ATM_ATM_ST	Q14676	MDC1	Q13315	ATM	S422	I426T	426	Missense	distal	4	no	13.385	12.810	EPSD	COSMIC	9.540	Down-regulation
Atypical_PIKK_ATM_ATM_ST	Q14676	MDC1	Q13315	ATM	S445	R444Q	444	Missense	proximal	-1	no	12.523	12.831	EPSD	COSMIC	9.540	Up-regulation
Atypical_PIKK_ATM_ATM_ST	Q14676	MDC1	Q13315	ATM	S445	T448I	448	Missense	distal	3	no	12.523	12.944	EPSD	COSMIC	9.540	Up-regulation
Atypical_PIKK_ATM_ATM_ST	Q14676	MDC1	Q13315	ATM	S505	H509P	509	Missense	distal	4	no	10.156	10.161	EPSD	COSMIC	9.540	Up-regulation
Atypical_PIKK_ATM_ATM_ST	Q14676	MDC1	Q13315	ATM	S505	D502Y	502	Missense	distal	-3	no	10.156	10.042	EPSD	COSMIC	9.540	Down-regulation
Atypical_PIKK_ATM_ATM_ST	Q14676	MDC1	Q13315	ATM	S513	H509P	509	Missense	distal	-4	no	14.104	14.115	EPSD	COSMIC	9.540	Up-regulation
Atypical_PIKK_ATM_ATM_ST	Q14676	MDC1	Q13315	ATM	S641	P639S	639	Missense	proximal	-2	no	9.770	10.006	EPSD	COSMIC	9.540	Up-regulation
Atypical_PIKK_ATM_ATM_ST	Q14676	MDC1	Q13315	ATM	S641	R642K	642	Missense	proximal	1	no	9.770	9.573	EPSD	COSMIC	9.540	Down-regulation
Atypical_PIKK_ATM_ATM_ST	Q14676	MDC1	Q13315	ATM	T659	Q662H	662	Missense	distal	3	no	13.856	13.996	EPSD	COSMIC	9.540	Up-regulation
Atypical_PIKK_ATM_ATM_ST	Q14676	MDC1	Q13315	ATM	T659	G665R	665	Missense	distal	6	no	13.856	13.857	EPSD	COSMIC	9.540	Up-regulation
Atypical_PIKK_ATM_ATM_ST	Q14676	MDC1	Q13315	ATM	T719	P726A	726	Missense	distal	7	no	13.846	13.858	EPSD	COSMIC	9.540	Up-regulation
Atypical_PIKK_ATM_ATM_ST	Q14676	MDC1	Q13315	ATM	S760	S763F	763	Missense	distal	3	no	9.817	10.399	EPSD	COSMIC;GDSC;CCLE	9.540	Up-regulation
Atypical_PIKK_ATM_ATM_ST	Q14676	MDC1	Q13315	ATM	T765	S763F	763	Missense	proximal	-2	no	12.124	11.224	EPSD	COSMIC;GDSC;CCLE	9.540	Down-regulation
Atypical_PIKK_ATM_ATM_ST	Q14676	MDC1	Q13315	ATM	S780	A784S	784	Missense	distal	4	no	9.675	10.022	EPSD	COSMIC	9.540	Up-regulation
Atypical_PIKK_ATM_ATM_ST	Q14676	MDC1	Q13315	ATM	S780	E773K	773	Missense	distal	-7	no	9.675	9.007	EPSD	COSMIC	9.540	Loss
Atypical_PIKK_ATM_ATM_ST	Q14676	MDC1	Q13315	ATM	S882	G878V	878	Missense	distal	-4	no	9.638	9.437	EPSD	COSMIC	9.540	Loss
Atypical_PIKK_ATM_ATM_ST	Q14676	MDC1	Q13315	ATM	S882	E888K	888	Missense	distal	6	no	9.638	9.592	EPSD	COSMIC	9.540	Down-regulation
Atypical_PIKK_ATM_ATM_ST	Q14676	MDC1	Q13315	ATM	T946	V940A	940	Missense	distal	-6	no	12.717	12.953	EPSD	COSMIC	9.540	Up-regulation
Atypical_PIKK_ATM_ATM_ST	Q14676	MDC1	Q13315	ATM	T946	T946I	946	Missense	central	0	yes	12.717	0.000	EPSD	COSMIC	9.540	Loss
Atypical_PIKK_ATM_ATM_ST	Q14676	MDC1	Q13315	ATM	T946	R948S	948	Missense	proximal	2	no	12.717	13.714	EPSD	COSMIC	9.540	Up-regulation
Atypical_PIKK_ATM_ATM_ST	Q14676	MDC1	Q13315	ATM	T946	Q947H	947	Missense	proximal	1	no	12.717	-2.192	EPSD	COSMIC	9.540	Loss
Atypical_PIKK_ATM_ATM_ST	Q14676	MDC1	Q13315	ATM	T946	D945Y	945	Missense	proximal	-1	no	12.717	12.722	EPSD	COSMIC	9.540	Up-regulation
Atypical_PIKK_ATM_ATM_ST	Q14676	MDC1	Q13315	ATM	S955	R948S	948	Missense	distal	-7	no	15.531	15.929	EPSD	COSMIC	9.540	Up-regulation
Atypical_PIKK_ATM_ATM_ST	Q14676	MDC1	Q13315	ATM	S964	P969R	969	Missense	distal	5	no	10.295	10.279	EPSD	COSMIC	9.540	Down-regulation
Atypical_PIKK_ATM_ATM_ST	Q14676	MDC1	Q13315	ATM	S964	P967L	967	Missense	distal	3	no	10.295	10.425	EPSD	COSMIC	9.540	Up-regulation
Atypical_PIKK_ATM_ATM_ST	Q14676	MDC1	Q13315	ATM	S964	P969A	969	Missense	distal	5	no	10.295	10.161	EPSD	COSMIC	9.540	Down-regulation
Atypical_PIKK_ATM_ATM_ST	Q14676	MDC1	Q13315	ATM	S988	P983S	983	Missense	distal	-5	no	12.287	12.283	EPSD	COSMIC	9.540	Down-regulation
Atypical_PIKK_ATM_ATM_ST	Q14676	MDC1	Q13315	ATM	S988	S986F	986	Missense	proximal	-2	no	12.287	11.387	EPSD	COSMIC	9.540	Down-regulation
Atypical_PIKK_ATM_ATM_ST	Q14676	MDC1	Q13315	ATM	S988	P985L	985	Missense	distal	-3	no	12.287	12.300	EPSD	COSMIC	9.540	Up-regulation
Atypical_PIKK_ATM_ATM_ST	Q14676	MDC1	Q13315	ATM	S988	S995F	995	Missense	distal	7	no	12.287	12.347	EPSD	COSMIC	9.540	Up-regulation
Atypical_PIKK_ATM_ATM_ST	Q14676	MDC1	Q13315	ATM	S988	S981A	981	Missense	distal	-7	no	12.287	12.190	EPSD	COSMIC	9.540	Down-regulation
Atypical_PIKK_ATM_ATM_ST	Q14676	MDC1	Q13315	ATM	S1033	D1030Y	1030	Missense	distal	-3	no	9.711	9.597	EPSD	COSMIC;GDSC;CCLE	9.540	Down-regulation
Atypical_PIKK_ATM_ATM_ST	Q14676	MDC1	Q13315	ATM	S1033	G1029D	1029	Missense	distal	-4	no	9.711	10.495	EPSD	COSMIC	9.540	Up-regulation
Atypical_PIKK_ATM_ATM_ST	Q14676	MDC1	Q13315	ATM	S1055	S1055A	1055	Missense	central	0	yes	14.808	0.000	EPSD	COSMIC	9.540	Loss
Atypical_PIKK_ATM_ATM_ST	Q14676	MDC1	Q13315	ATM	S1055	L1053F	1053	Missense	proximal	-2	no	14.808	14.297	EPSD	COSMIC	9.540	Down-regulation
Atypical_PIKK_ATM_ATM_ST	Q14676	MDC1	Q13315	ATM	S1055	P1052L	1052	Missense	distal	-3	no	14.808	14.821	EPSD	COSMIC	9.540	Up-regulation
Atypical_PIKK_ATM_ATM_ST	Q14676	MDC1	Q13315	ATM	S1055	S1055F	1055	Missense	central	0	yes	14.808	0.000	EPSD	COSMIC	9.540	Loss
Atypical_PIKK_ATM_ATM_ST	Q14676	MDC1	Q13315	ATM	S1057	S1055A	1055	Missense	proximal	-2	no	13.905	13.718	EPSD	COSMIC	9.540	Down-regulation
Atypical_PIKK_ATM_ATM_ST	Q14676	MDC1	Q13315	ATM	S1057	L1053F	1053	Missense	distal	-4	no	13.905	13.446	EPSD	COSMIC	9.540	Down-regulation
Atypical_PIKK_ATM_ATM_ST	Q14676	MDC1	Q13315	ATM	S1057	P1052L	1052	Missense	distal	-5	no	13.905	13.924	EPSD	COSMIC	9.540	Up-regulation
Atypical_PIKK_ATM_ATM_ST	Q14676	MDC1	Q13315	ATM	S1057	P1064L	1064	Missense	distal	7	no	13.905	13.906	EPSD	COSMIC	9.540	Up-regulation
Atypical_PIKK_ATM_ATM_ST	Q14676	MDC1	Q13315	ATM	S1057	S1055F	1055	Missense	proximal	-2	no	13.905	13.005	EPSD	COSMIC	9.540	Down-regulation
Atypical_PIKK_ATM_ATM_ST	Q14676	MDC1	Q13315	ATM	S1057	P1063H	1063	Missense	distal	6	no	13.905	13.883	EPSD	COSMIC	9.540	Down-regulation
Atypical_PIKK_ATM_ATM_ST	Q14676	MDC1	Q13315	ATM	S1086	R1079C	1079	Missense	distal	-7	no	14.346	14.071	EPSD	COSMIC	9.540	Down-regulation
Atypical_PIKK_ATM_ATM_ST	Q14676	MDC1	Q13315	ATM	S1086	R1079H	1079	Missense	distal	-7	no	14.346	14.432	EPSD	COSMIC	9.540	Up-regulation
Atypical_PIKK_ATM_ATM_ST	Q14676	MDC1	Q13315	ATM	S1086	P1090L	1090	Missense	distal	4	no	14.346	14.566	EPSD	COSMIC	9.540	Up-regulation
Atypical_PIKK_ATM_ATM_ST	Q14676	MDC1	Q13315	ATM	S1086	E1088V	1088	Missense	proximal	2	no	14.346	12.944	EPSD	COSMIC	9.540	Down-regulation
Atypical_PIKK_ATM_ATM_ST	Q14676	MDC1	Q13315	ATM	S1143	T1138S	1138	Missense	distal	-5	no	13.606	13.694	EPSD	COSMIC	9.540	Up-regulation
Atypical_PIKK_ATM_ATM_ST	Q14676	MDC1	Q13315	ATM	S1143	T1142A	1142	Missense	proximal	-1	no	13.606	13.435	EPSD	COSMIC	9.540	Down-regulation
Atypical_PIKK_ATM_ATM_ST	Q14676	MDC1	Q13315	ATM	S1143	A1145T	1145	Missense	proximal	2	no	13.606	13.927	EPSD	COSMIC	9.540	Up-regulation
Atypical_PIKK_ATM_ATM_ST	Q14676	MDC1	Q13315	ATM	T1157	V1155L	1155	Missense	proximal	-2	no	10.445	10.720	EPSD	COSMIC	9.540	Up-regulation
Atypical_PIKK_ATM_ATM_ST	Q14676	MDC1	Q13315	ATM	T1157	P1160L	1160	Missense	distal	3	no	10.445	10.575	EPSD	COSMIC	9.540	Up-regulation
Atypical_PIKK_ATM_ATM_ST	Q14676	MDC1	Q13315	ATM	S1184	T1187S	1187	Missense	distal	3	no	13.570	13.490	EPSD	COSMIC	9.540	Down-regulation
Atypical_PIKK_ATM_ATM_ST	Q14676	MDC1	Q13315	ATM	S1184	T1179I	1179	Missense	distal	-5	no	13.570	13.773	EPSD	COSMIC	9.540	Up-regulation
Atypical_PIKK_ATM_ATM_ST	Q14676	MDC1	Q13315	ATM	S1184	V1186A	1186	Missense	proximal	2	no	13.570	13.879	EPSD	COSMIC	9.540	Up-regulation
Atypical_PIKK_ATM_ATM_ST	Q14676	MDC1	Q13315	ATM	S1184	S1184Y	1184	Missense	central	0	yes	13.570	0.000	EPSD	COSMIC	9.540	Loss
Atypical_PIKK_ATM_ATM_ST	Q14676	MDC1	Q13315	ATM	S1184	P1177S	1177	Missense	distal	-7	no	13.570	13.806	EPSD	COSMIC;GDSC	9.540	Up-regulation
Atypical_PIKK_ATM_ATM_ST	Q14676	MDC1	Q13315	ATM	S1184	S1180P	1180	Missense	distal	-4	no	13.570	12.901	EPSD	COSMIC	9.540	Down-regulation
Atypical_PIKK_ATM_ATM_ST	Q14676	MDC1	Q13315	ATM	S1184	Q1185H	1185	Missense	proximal	1	no	13.570	-1.339	EPSD	COSMIC;GDSC;CCLE	9.540	Loss
Atypical_PIKK_ATM_ATM_ST	Q14676	MDC1	Q13315	ATM	T1198	S1194F	1194	Missense	distal	-4	no	10.825	9.426	EPSD	COSMIC	9.540	Loss
Atypical_PIKK_ATM_ATM_ST	Q14676	MDC1	Q13315	ATM	T1198	S1192N	1192	Missense	distal	-6	no	10.825	10.709	EPSD	COSMIC	9.540	Down-regulation
Atypical_PIKK_ATM_ATM_ST	Q14676	MDC1	Q13315	ATM	T1198	T1198I	1198	Missense	central	0	yes	10.825	0.000	EPSD	COSMIC	9.540	Loss
Atypical_PIKK_ATM_ATM_ST	Q14676	MDC1	Q13315	ATM	T1198	V1196I	1196	Missense	proximal	-2	no	10.825	10.800	EPSD	COSMIC	9.540	Down-regulation
Atypical_PIKK_ATM_ATM_ST	Q14676	MDC1	Q13315	ATM	T1198	P1204S	1204	Missense	distal	6	no	10.825	10.836	EPSD	COSMIC	9.540	Up-regulation
Atypical_PIKK_ATM_ATM_ST	Q14676	MDC1	Q13315	ATM	S1212	T1213A	1213	Missense	proximal	1	no	7.103	10.039	EPSD	COSMIC	9.540	Gain
Atypical_PIKK_ATM_ATM_ST	Q14676	MDC1	Q13315	ATM	S1225	R1229M	1229	Missense	distal	4	no	13.833	13.912	EPSD	COSMIC	9.540	Up-regulation
Atypical_PIKK_ATM_ATM_ST	Q14676	MDC1	Q13315	ATM	T1280	P1283T	1283	Missense	distal	3	no	10.583	10.512	EPSD	COSMIC	9.540	Down-regulation
Atypical_PIKK_ATM_ATM_ST	Q14676	MDC1	Q13315	ATM	T1280	N1274S	1274	Missense	distal	-6	no	10.583	10.699	EPSD	COSMIC	9.540	Up-regulation
Atypical_PIKK_ATM_ATM_ST	Q14676	MDC1	Q13315	ATM	T1280	S1277F	1277	Missense	distal	-3	no	10.583	11.655	EPSD	COSMIC	9.540	Up-regulation
Atypical_PIKK_ATM_ATM_ST	Q14676	MDC1	Q13315	ATM	T1321	S1318F	1318	Missense	distal	-3	no	10.241	11.313	EPSD	COSMIC	9.540	Up-regulation
Atypical_PIKK_ATM_ATM_ST	Q14676	MDC1	Q13315	ATM	T1321	T1324P	1324	Missense	distal	3	no	10.241	10.313	EPSD	COSMIC	9.540	Up-regulation
Atypical_PIKK_ATM_ATM_ST	Q14676	MDC1	Q13315	ATM	T1321	M1316V	1316	Missense	distal	-5	no	10.241	10.270	EPSD	COSMIC	9.540	Up-regulation
Atypical_PIKK_ATM_ATM_ST	Q14676	MDC1	Q13315	ATM	T1321	S1318A	1318	Missense	distal	-3	no	10.241	9.796	EPSD	COSMIC	9.540	Down-regulation
Atypical_PIKK_ATM_ATM_ST	Q14676	MDC1	Q13315	ATM	T1321	P1327R	1327	Missense	distal	6	no	10.241	10.235	EPSD	COSMIC	9.540	Down-regulation
Atypical_PIKK_ATM_ATM_ST	Q14676	MDC1	Q13315	ATM	T1321	M1316T	1316	Missense	distal	-5	no	10.241	10.068	EPSD	COSMIC	9.540	Down-regulation
Atypical_PIKK_ATM_ATM_ST	Q14676	MDC1	Q13315	ATM	S1335	T1336P	1336	Missense	proximal	1	no	7.049	12.056	EPSD	COSMIC	9.540	Gain
Atypical_PIKK_ATM_ATM_ST	Q14676	MDC1	Q13315	ATM	S1348	R1349Q	1349	Missense	proximal	1	no	6.939	13.590	EPSD	COSMIC	9.540	Gain
Atypical_PIKK_ATM_ATM_ST	Q14676	MDC1	Q13315	ATM	T1403	P1409L	1409	Missense	distal	6	no	10.104	10.059	EPSD	COSMIC	9.540	Down-regulation
Atypical_PIKK_ATM_ATM_ST	Q14676	MDC1	Q13315	ATM	T1403	G1401C	1401	Missense	proximal	-2	no	10.104	10.085	EPSD	COSMIC	9.540	Down-regulation
Atypical_PIKK_ATM_ATM_ST	Q14676	MDC1	Q13315	ATM	T1403	R1398I	1398	Missense	distal	-5	no	10.104	10.143	EPSD	COSMIC	9.540	Up-regulation
Atypical_PIKK_ATM_ATM_ST	Q14676	MDC1	Q13315	ATM	S1430	T1433P	1433	Missense	distal	3	no	13.024	13.096	EPSD	COSMIC	9.540	Up-regulation
Atypical_PIKK_ATM_ATM_ST	Q14676	MDC1	Q13315	ATM	S1430	P1428S	1428	Missense	proximal	-2	no	13.024	13.261	EPSD	COSMIC	9.540	Up-regulation
Atypical_PIKK_ATM_ATM_ST	Q14676	MDC1	Q13315	ATM	S1430	R1434S	1434	Missense	distal	4	no	13.024	12.842	EPSD	COSMIC	9.540	Down-regulation
Atypical_PIKK_ATM_ATM_ST	Q14676	MDC1	Q13315	ATM	S1430	Q1431E	1431	Missense	proximal	1	no	13.024	7.128	EPSD	COSMIC	9.540	Loss
Atypical_PIKK_ATM_ATM_ST	Q14676	MDC1	Q13315	ATM	S1430	R1436T	1436	Missense	distal	6	no	13.024	13.032	EPSD	COSMIC	9.540	Up-regulation
Atypical_PIKK_ATM_ATM_ST	Q14676	MDC1	Q13315	ATM	S1430	P1428H	1428	Missense	proximal	-2	no	13.024	12.834	EPSD	COSMIC	9.540	Down-regulation
Atypical_PIKK_ATM_ATM_ST	Q14676	MDC1	Q13315	ATM	T1444	R1439K	1439	Missense	distal	-5	no	10.398	10.239	EPSD	COSMIC	9.540	Down-regulation
Atypical_PIKK_ATM_ATM_ST	Q14676	MDC1	Q13315	ATM	S1458	T1459P	1459	Missense	proximal	1	no	7.115	12.122	EPSD	COSMIC	9.540	Gain
Atypical_PIKK_ATM_ATM_ST	Q14676	MDC1	Q13315	ATM	S1471	T1470A	1470	Missense	proximal	-1	no	13.254	13.083	EPSD	COSMIC	9.540	Down-regulation
Atypical_PIKK_ATM_ATM_ST	Q14676	MDC1	Q13315	ATM	S1471	Q1472K	1472	Missense	proximal	1	no	13.254	6.405	EPSD	COSMIC	9.540	Loss
Atypical_PIKK_ATM_ATM_ST	Q14676	MDC1	Q13315	ATM	S1471	S1471F	1471	Missense	central	0	yes	13.254	0.000	EPSD	COSMIC	9.540	Loss
Atypical_PIKK_ATM_ATM_ST	Q14676	MDC1	Q13315	ATM	S1471	P1469S	1469	Missense	proximal	-2	no	13.254	13.490	EPSD	COSMIC	9.540	Up-regulation
Atypical_PIKK_ATM_ATM_ST	Q14676	MDC1	Q13315	ATM	S1471	V1465L	1465	Missense	distal	-6	no	13.254	13.222	EPSD	COSMIC	9.540	Down-regulation
Atypical_PIKK_ATM_ATM_ST	Q14676	MDC1	Q13315	ATM	T1485	T1488R	1488	Missense	distal	3	no	10.500	10.605	EPSD	COSMIC	9.540	Up-regulation
Atypical_PIKK_ATM_ATM_ST	Q14676	MDC1	Q13315	ATM	T1485	V1483I	1483	Missense	proximal	-2	no	10.500	10.475	EPSD	COSMIC	9.540	Down-regulation
Atypical_PIKK_ATM_ATM_ST	Q14676	MDC1	Q13315	ATM	T1485	T1488P	1488	Missense	distal	3	no	10.500	10.572	EPSD	COSMIC	9.540	Up-regulation
Atypical_PIKK_ATM_ATM_ST	Q14676	MDC1	Q13315	ATM	T1485	D1479H	1479	Missense	distal	-6	no	10.500	10.348	EPSD	COSMIC	9.540	Down-regulation
Atypical_PIKK_ATM_ATM_ST	Q14676	MDC1	Q13315	ATM	T1485	P1486T	1486	Missense	proximal	1	no	10.500	5.493	EPSD	COSMIC	9.540	Loss
Atypical_PIKK_ATM_ATM_ST	Q14676	MDC1	Q13315	ATM	T1485	S1481T	1481	Missense	distal	-4	no	10.500	10.117	EPSD	COSMIC	9.540	Down-regulation
Atypical_PIKK_ATM_ATM_ST	Q14676	MDC1	Q13315	ATM	S1499	P1494H	1494	Missense	distal	-5	no	10.190	10.235	EPSD	COSMIC	9.540	Up-regulation
Atypical_PIKK_ATM_ATM_ST	Q14676	MDC1	Q13315	ATM	S1499	A1500T	1500	Missense	proximal	1	no	10.190	7.255	EPSD	COSMIC	9.540	Loss
Atypical_PIKK_ATM_ATM_ST	Q14676	MDC1	Q13315	ATM	S1499	D1503N	1503	Missense	distal	4	no	10.190	10.110	EPSD	COSMIC	9.540	Down-regulation
Atypical_PIKK_ATM_ATM_ST	Q14676	MDC1	Q13315	ATM	T1526	R1521W	1521	Missense	distal	-5	no	10.241	10.406	EPSD	COSMIC	9.540	Up-regulation
Atypical_PIKK_ATM_ATM_ST	Q14676	MDC1	Q13315	ATM	T1526	A1533E	1533	Missense	distal	7	no	10.241	10.206	EPSD	COSMIC	9.540	Down-regulation
Atypical_PIKK_ATM_ATM_ST	Q14676	MDC1	Q13315	ATM	S1553	R1554Q	1554	Missense	proximal	1	no	6.329	12.981	EPSD	COSMIC	9.540	Gain
Atypical_PIKK_ATM_ATM_ST	Q14676	MDC1	Q13315	ATM	T1567	R1562T	1562	Missense	distal	-5	no	10.640	10.476	EPSD	COSMIC	9.540	Down-regulation
Atypical_PIKK_ATM_ATM_ST	Q14676	MDC1	Q13315	ATM	T1567	I1574V	1574	Missense	distal	7	no	10.640	10.658	EPSD	COSMIC	9.540	Up-regulation
Atypical_PIKK_ATM_ATM_ST	Q14676	MDC1	Q13315	ATM	T1567	R1562M	1562	Missense	distal	-5	no	10.640	10.649	EPSD	COSMIC	9.540	Up-regulation
Atypical_PIKK_ATM_ATM_ST	Q14676	MDC1	Q13315	ATM	T1567	P1573A	1573	Missense	distal	6	no	10.640	10.658	EPSD	COSMIC	9.540	Up-regulation
Atypical_PIKK_ATM_ATM_ST	Q14676	MDC1	Q13315	ATM	T1608	T1601I	1601	Missense	distal	-7	no	10.316	9.732	EPSD	COSMIC	9.540	Down-regulation
Atypical_PIKK_ATM_ATM_ST	Q14676	MDC1	Q13315	ATM	T1608	T1615I	1615	Missense	distal	7	no	10.316	10.330	EPSD	COSMIC;GDSC;CCLE	9.540	Up-regulation
Atypical_PIKK_ATM_ATM_ST	Q14676	MDC1	Q13315	ATM	T1608	S1604F	1604	Missense	distal	-4	no	10.316	8.917	EPSD	COSMIC	9.540	Loss
Atypical_PIKK_ATM_ATM_ST	Q14676	MDC1	Q13315	ATM	T1608	P1609A	1609	Missense	proximal	1	no	10.316	8.244	EPSD	COSMIC	9.540	Loss
Atypical_PIKK_ATM_ATM_ST	Q14676	MDC1	Q13315	ATM	T1716	I1710M	1710	Missense	distal	-6	no	11.815	11.970	EPSD	COSMIC	9.540	Up-regulation
Atypical_PIKK_ATM_ATM_ST	Q14676	MDC1	Q13315	ATM	T1716	P1718L	1718	Missense	proximal	2	no	11.815	11.026	EPSD	COSMIC	9.540	Down-regulation
Atypical_PIKK_ATM_ATM_ST	Q14676	MDC1	Q13315	ATM	S1786	K1790R	1790	Missense	distal	4	no	12.057	12.159	EPSD	COSMIC	9.540	Up-regulation
Atypical_PIKK_ATM_ATM_ST	Q14676	MDC1	Q13315	ATM	S1786	K1790M	1790	Missense	distal	4	no	12.057	12.238	EPSD	COSMIC	9.540	Up-regulation
Atypical_PIKK_ATM_ATM_ST	Q14676	MDC1	Q13315	ATM	T1800	P1801Q	1801	Missense	proximal	1	no	7.820	12.622	EPSD	COSMIC	9.540	Gain
Atypical_PIKK_ATM_ATM_ST	Q14676	MDC1	Q13315	ATM	S1833	V1837M	1837	Missense	distal	4	no	13.180	13.135	EPSD	COSMIC	9.540	Down-regulation
Atypical_PIKK_ATM_ATM_ST	Q14676	MDC1	Q13315	ATM	S1833	S1833F	1833	Missense	central	0	yes	13.180	0.000	EPSD	COSMIC	9.540	Loss
Atypical_PIKK_ATM_ATM_ST	Q16665	HIF1A	Q13315	ATM	T123	V116E	116	Missense	distal	-7	no	8.978	9.814	EPSD	COSMIC	9.540	Gain
Atypical_PIKK_ATM_ATM_ST	Q16665	HIF1A	Q13315	ATM	S247	R245Q	245	Missense	proximal	-2	no	10.649	10.967	EPSD	COSMIC	9.540	Up-regulation
Atypical_PIKK_ATM_ATM_ST	Q16665	HIF1A	Q13315	ATM	S247	Y254N	254	Missense	distal	7	no	10.649	10.630	EPSD	COSMIC	9.540	Down-regulation
Atypical_PIKK_ATM_ATM_ST	Q16665	HIF1A	Q13315	ATM	S247	F242V	242	Missense	distal	-5	no	10.649	10.438	EPSD	COSMIC	9.540	Down-regulation
Atypical_PIKK_ATM_ATM_ST	Q16665	HIF1A	Q13315	ATM	S247	M250I	250	Missense	distal	3	no	10.649	10.894	EPSD	COSMIC	9.540	Up-regulation
Atypical_PIKK_ATM_ATM_ST	Q16665	HIF1A	Q13315	ATM	S247	K251N	251	Missense	distal	4	no	10.649	10.696	EPSD	COSMIC	9.540	Up-regulation
Atypical_PIKK_ATM_ATM_ST	Q16665	HIF1A	Q13315	ATM	S500	Q497H	497	Missense	distal	-3	no	9.602	9.731	EPSD	COSMIC	9.540	Up-regulation
Atypical_PIKK_ATM_ATM_ST	Q16665	HIF1A	Q13315	ATM	S500	R507K	507	Missense	distal	7	no	9.602	9.590	EPSD	COSMIC	9.540	Down-regulation
Atypical_PIKK_ATM_ATM_ST	Q16665	HIF1A	Q13315	ATM	S500	P501L	501	Missense	proximal	1	no	9.602	8.047	EPSD	COSMIC	9.540	Loss
Atypical_PIKK_ATM_ATM_ST	Q16665	HIF1A	Q13315	ATM	S500	Q495K	495	Missense	distal	-5	no	9.602	9.652	EPSD	COSMIC	9.540	Up-regulation
Atypical_PIKK_ATM_ATM_ST	Q16665	HIF1A	Q13315	ATM	S500	Q495R	495	Missense	distal	-5	no	9.602	9.811	EPSD	COSMIC	9.540	Up-regulation
Atypical_PIKK_ATM_ATM_ST	Q16665	HIF1A	Q13315	ATM	S500	D503N	503	Missense	distal	3	no	9.602	9.619	EPSD	COSMIC	9.540	Up-regulation
Atypical_PIKK_ATM_ATM_ST	Q16665	HIF1A	Q13315	ATM	S510	R507K	507	Missense	distal	-3	no	11.439	10.607	EPSD	COSMIC	9.540	Down-regulation
Atypical_PIKK_ATM_ATM_ST	Q16665	HIF1A	Q13315	ATM	S510	E512V	512	Missense	proximal	2	no	11.439	10.037	EPSD	COSMIC;GDSC	9.540	Down-regulation
Atypical_PIKK_ATM_ATM_ST	Q16665	HIF1A	Q13315	ATM	S510	P516H	516	Missense	distal	6	no	11.439	11.417	EPSD	COSMIC	9.540	Down-regulation
Atypical_PIKK_ATM_ATM_ST	Q16665	HIF1A	Q13315	ATM	S510	S517T	517	Missense	distal	7	no	11.439	11.456	EPSD	COSMIC	9.540	Up-regulation
Atypical_PIKK_ATM_ATM_ST	Q16665	HIF1A	Q13315	ATM	S510	D503N	503	Missense	distal	-7	no	11.439	11.475	EPSD	COSMIC	9.540	Up-regulation
Atypical_PIKK_ATM_ATM_ST	Q16665	HIF1A	Q13315	ATM	S515	E512V	512	Missense	distal	-3	no	9.638	10.216	EPSD	COSMIC;GDSC	9.540	Up-regulation
Atypical_PIKK_ATM_ATM_ST	Q16665	HIF1A	Q13315	ATM	S515	P516H	516	Missense	proximal	1	no	9.638	-0.469	EPSD	COSMIC	9.540	Loss
Atypical_PIKK_ATM_ATM_ST	Q16665	HIF1A	Q13315	ATM	S515	S517T	517	Missense	proximal	2	no	9.638	9.376	EPSD	COSMIC	9.540	Loss
Atypical_PIKK_ATM_ATM_ST	Q16665	HIF1A	Q13315	ATM	S515	Y522H	522	Missense	distal	7	no	9.638	9.633	EPSD	COSMIC	9.540	Down-regulation
Atypical_PIKK_ATM_ATM_ST	Q16665	HIF1A	Q13315	ATM	S641	I635F	635	Missense	distal	-6	no	9.750	9.619	EPSD	COSMIC	9.540	Down-regulation
Atypical_PIKK_ATM_ATM_ST	Q16665	HIF1A	Q13315	ATM	S641	A640P	640	Missense	proximal	-1	no	9.750	9.618	EPSD	COSMIC;GDSC	9.540	Down-regulation
Atypical_PIKK_ATM_ATM_ST	Q16665	HIF1A	Q13315	ATM	S641	P642S	642	Missense	proximal	1	no	9.750	2.774	EPSD	COSMIC	9.540	Loss
Atypical_PIKK_ATM_ATM_ST	Q16665	HIF1A	Q13315	ATM	S641	K636N	636	Missense	distal	-5	no	9.750	9.805	EPSD	COSMIC	9.540	Up-regulation
Atypical_PIKK_ATM_ATM_ST	Q16665	HIF1A	Q13315	ATM	S668	R671K	671	Missense	distal	3	no	10.294	10.222	EPSD	COSMIC	9.540	Down-regulation
Atypical_PIKK_ATM_ATM_ST	Q16665	HIF1A	Q13315	ATM	S668	T666S	666	Missense	proximal	-2	no	10.294	10.382	EPSD	COSMIC	9.540	Up-regulation
Atypical_PIKK_ATM_ATM_ST	Q16665	HIF1A	Q13315	ATM	S668	A672V	672	Missense	distal	4	no	10.294	10.947	EPSD	COSMIC	9.540	Up-regulation
Atypical_PIKK_ATM_ATM_ST	Q16665	HIF1A	Q13315	ATM	S696	P702T	702	Missense	distal	6	no	14.876	14.877	PhosphoSitePlus	COSMIC;GDSC;CCLE	9.540	Up-regulation
Atypical_PIKK_ATM_ATM_ST	Q16665	HIF1A	Q13315	ATM	S696	V690M	690	Missense	distal	-6	no	14.876	14.887	PhosphoSitePlus	COSMIC	9.540	Up-regulation
Atypical_PIKK_ATM_ATM_ST	Q16665	HIF1A	Q13315	ATM	S696	P702L	702	Missense	distal	6	no	14.876	14.831	PhosphoSitePlus	COSMIC	9.540	Down-regulation
Atypical_PIKK_ATM_ATM_ST	Q16665	HIF1A	Q13315	ATM	S696	A694T	694	Missense	proximal	-2	no	14.876	14.976	PhosphoSitePlus	COSMIC;GDSC	9.540	Up-regulation
Atypical_PIKK_ATM_ATM_ST	Q16665	HIF1A	Q13315	ATM	S696	Q697E	697	Missense	proximal	1	no	14.876	8.979	PhosphoSitePlus	COSMIC;GDSC;CCLE	9.540	Loss
Atypical_PIKK_ATM_ATM_ST	Q16665	HIF1A	Q13315	ATM	S696	N689I	689	Missense	distal	-7	no	14.876	14.398	PhosphoSitePlus	COSMIC	9.540	Down-regulation
Atypical_PIKK_ATM_ATM_ST	Q16665	HIF1A	Q13315	ATM	S696	S692F	692	Missense	distal	-4	no	14.876	13.477	PhosphoSitePlus	COSMIC	9.540	Down-regulation
Atypical_PIKK_ATM_ATM_ST	Q16665	HIF1A	Q13315	ATM	S809	N803D	803	Missense	distal	-6	no	9.557	9.645	EPSD	COSMIC	9.540	Up-regulation
Atypical_PIKK_ATM_ATM_ST	Q16665	HIF1A	Q13315	ATM	S809	L813P	813	Missense	distal	4	no	9.557	9.337	EPSD	COSMIC	9.540	Loss
Atypical_PIKK_ATM_ATM_ST	Q16665	HIF1A	Q13315	ATM	S809	S809N	809	Missense	central	0	yes	9.557	0.000	EPSD	COSMIC	9.540	Loss
Atypical_PIKK_ATM_ATM_ST	Q16665	HIF1A	Q13315	ATM	S809	G808V	808	Missense	proximal	-1	no	9.557	9.325	EPSD	COSMIC	9.540	Loss
Atypical_PIKK_ATM_ATM_ST	Q16665	HIF1A	Q13315	ATM	S809	I806V	806	Missense	distal	-3	no	9.557	9.305	EPSD	COSMIC	9.540	Loss
Atypical_PIKK_ATM_ATM_ST	Q16665	HIF1A	Q13315	ATM	S809	P805A	805	Missense	distal	-4	no	9.557	9.716	EPSD	COSMIC	9.540	Up-regulation
Atypical_PIKK_ATM_ATM_ST	Q9H7Z6	KAT8	Q13315	ATM	S42	S37T	37	Missense	distal	-5	no	11.225	11.136	EPSD	COSMIC	9.540	Down-regulation
Atypical_PIKK_ATM_ATM_ST	Q9H7Z6	KAT8	Q13315	ATM	S348	K341R	341	Missense	distal	-7	no	10.635	10.549	EPSD	COSMIC	9.540	Down-regulation
Atypical_PIKK_ATM_ATM_ST	Q9H7Z6	KAT8	Q13315	ATM	S348	P349Q	349	Missense	proximal	1	no	10.635	15.437	EPSD	COSMIC	9.540	Up-regulation
Atypical_PIKK_ATM_ATM_ST	Q9H7Z6	KAT8	Q13315	ATM	S348	G347D	347	Missense	proximal	-1	no	10.635	10.773	EPSD	COSMIC	9.540	Up-regulation
Atypical_PIKK_ATM_ATM_ST	Q9H7Z6	KAT8	Q13315	ATM	S386	D384V	384	Missense	proximal	-2	no	12.454	12.088	EPSD	COSMIC	9.540	Down-regulation
Atypical_PIKK_ATM_ATM_ST	Q9H7Z6	KAT8	Q13315	ATM	S386	S390R	390	Missense	distal	4	no	12.454	12.636	EPSD	COSMIC	9.540	Up-regulation
Atypical_PIKK_ATM_ATM_ST	Q9H7Z6	KAT8	Q13315	ATM	T392	S390R	390	Missense	proximal	-2	no	14.580	14.137	PhosphoSitePlus	COSMIC	9.540	Down-regulation
Atypical_PIKK_ATM_ATM_ST	Q9H7Z6	KAT8	Q13315	ATM	S456	K457E	457	Missense	proximal	1	no	9.689	10.640	EPSD	COSMIC	9.540	Up-regulation
Atypical_PIKK_ATM_ATM_ST	Q14694	USP10	Q13315	ATM	S35	G41D	41	Missense	distal	6	no	9.580	9.577	EPSD	COSMIC	9.540	Down-regulation
Atypical_PIKK_ATM_ATM_ST	Q14694	USP10	Q13315	ATM	S35	L39V	39	Missense	distal	4	no	9.580	9.544	EPSD	COSMIC	9.540	Down-regulation
Atypical_PIKK_ATM_ATM_ST	Q14694	USP10	Q13315	ATM	T42	G41D	41	Missense	proximal	-1	no	12.288	12.425	PhosphoSitePlus;EPSD	COSMIC	9.540	Up-regulation
Atypical_PIKK_ATM_ATM_ST	Q14694	USP10	Q13315	ATM	T42	L39V	39	Missense	distal	-3	no	12.288	12.498	PhosphoSitePlus;EPSD	COSMIC	9.540	Up-regulation
Atypical_PIKK_ATM_ATM_ST	Q14694	USP10	Q13315	ATM	S211	D217N	217	Missense	distal	6	no	9.560	9.571	EPSD	COSMIC	9.540	Up-regulation
Atypical_PIKK_ATM_ATM_ST	Q14694	USP10	Q13315	ATM	S211	T216S	216	Missense	distal	5	no	9.560	9.576	EPSD	COSMIC;GDSC;CCLE	9.540	Up-regulation
Atypical_PIKK_ATM_ATM_ST	Q14694	USP10	Q13315	ATM	S319	A320P	320	Missense	proximal	1	no	9.325	11.397	EPSD	COSMIC	9.540	Gain
Atypical_PIKK_ATM_ATM_ST	Q14694	USP10	Q13315	ATM	S321	P323A	323	Missense	proximal	2	no	10.326	10.197	EPSD	COSMIC;GDSC;CCLE	9.540	Down-regulation
Atypical_PIKK_ATM_ATM_ST	Q14694	USP10	Q13315	ATM	S321	D325E	325	Missense	distal	4	no	10.326	9.820	EPSD	COSMIC	9.540	Down-regulation
Atypical_PIKK_ATM_ATM_ST	Q14694	USP10	Q13315	ATM	S321	A320P	320	Missense	proximal	-1	no	10.326	10.194	EPSD	COSMIC	9.540	Down-regulation
Atypical_PIKK_ATM_ATM_ST	Q14694	USP10	Q13315	ATM	S321	E318D	318	Missense	distal	-3	no	10.326	10.731	EPSD	COSMIC	9.540	Up-regulation
Atypical_PIKK_ATM_ATM_ST	Q14694	USP10	Q13315	ATM	S331	D325E	325	Missense	distal	-6	no	10.845	11.059	EPSD	COSMIC	9.540	Up-regulation
Atypical_PIKK_ATM_ATM_ST	Q14694	USP10	Q13315	ATM	S331	A330S	330	Missense	proximal	-1	no	10.845	11.005	EPSD	COSMIC	9.540	Up-regulation
Atypical_PIKK_ATM_ATM_ST	Q14694	USP10	Q13315	ATM	S331	G332V	332	Missense	proximal	1	no	10.845	4.324	EPSD	COSMIC	9.540	Loss
Atypical_PIKK_ATM_ATM_ST	Q14694	USP10	Q13315	ATM	S337	A330S	330	Missense	distal	-7	no	15.641	15.738	EPSD;PhosphoSitePlus	COSMIC	9.540	Up-regulation
Atypical_PIKK_ATM_ATM_ST	Q14694	USP10	Q13315	ATM	S337	G332V	332	Missense	distal	-5	no	15.641	15.700	EPSD;PhosphoSitePlus	COSMIC	9.540	Up-regulation
Atypical_PIKK_ATM_ATM_ST	Q14694	USP10	Q13315	ATM	S355	E361A	361	Missense	distal	6	no	10.172	10.154	EPSD	COSMIC	9.540	Down-regulation
Atypical_PIKK_ATM_ATM_ST	Q14694	USP10	Q13315	ATM	S355	S349Y	349	Missense	distal	-6	no	10.172	9.923	EPSD	COSMIC	9.540	Down-regulation
Atypical_PIKK_ATM_ATM_ST	Q14694	USP10	Q13315	ATM	S355	P356L	356	Missense	proximal	1	no	10.172	8.618	EPSD	COSMIC	9.540	Loss
Atypical_PIKK_ATM_ATM_ST	Q14694	USP10	Q13315	ATM	S365	S365P	365	Missense	central	0	yes	11.670	0.000	EPSD	COSMIC;GDSC	9.540	Loss
Atypical_PIKK_ATM_ATM_ST	Q14694	USP10	Q13315	ATM	S365	E361A	361	Missense	distal	-4	no	11.670	10.881	EPSD	COSMIC	9.540	Down-regulation
Atypical_PIKK_ATM_ATM_ST	Q14694	USP10	Q13315	ATM	S365	P371S	371	Missense	distal	6	no	11.670	11.681	EPSD	COSMIC	9.540	Up-regulation
Atypical_PIKK_ATM_ATM_ST	Q14694	USP10	Q13315	ATM	S516	G519D	519	Missense	distal	3	no	9.556	9.609	EPSD	COSMIC	9.540	Up-regulation
Atypical_PIKK_ATM_ATM_ST	Q14694	USP10	Q13315	ATM	S718	I712M	712	Missense	distal	-6	no	9.409	9.564	EPSD	COSMIC	9.540	Gain
Atypical_PIKK_ATM_ATM_ST	Q14694	USP10	Q13315	ATM	S718	G720E	720	Missense	proximal	2	no	9.409	10.778	EPSD	COSMIC	9.540	Gain
Atypical_PIKK_ATM_ATM_ST	Q09472	EP300	Q13315	ATM	S20	A13T	13	Missense	distal	-7	no	9.820	9.836	EPSD	COSMIC	9.540	Up-regulation
Atypical_PIKK_ATM_ATM_ST	Q09472	EP300	Q13315	ATM	S20	P21L	21	Missense	proximal	1	no	9.820	8.266	EPSD	COSMIC	9.540	Loss
Atypical_PIKK_ATM_ATM_ST	Q09472	EP300	Q13315	ATM	S20	A13V	13	Missense	distal	-7	no	9.820	9.437	EPSD	COSMIC	9.540	Loss
Atypical_PIKK_ATM_ATM_ST	Q09472	EP300	Q13315	ATM	S26	G30V	30	Missense	distal	4	no	10.301	10.477	EPSD	COSMIC;CCLE	9.540	Up-regulation
Atypical_PIKK_ATM_ATM_ST	Q09472	EP300	Q13315	ATM	S26	G30D	30	Missense	distal	4	no	10.301	10.379	EPSD	COSMIC	9.540	Up-regulation
Atypical_PIKK_ATM_ATM_ST	Q09472	EP300	Q13315	ATM	S26	P21L	21	Missense	distal	-5	no	10.301	10.320	EPSD	COSMIC	9.540	Up-regulation
Atypical_PIKK_ATM_ATM_ST	Q09472	EP300	Q13315	ATM	S106	S112N	112	Missense	distal	6	no	15.018	15.008	PhosphoSitePlus	COSMIC	9.540	Down-regulation
Atypical_PIKK_ATM_ATM_ST	Q09472	EP300	Q13315	ATM	S106	A108V	108	Missense	proximal	2	no	15.018	14.709	PhosphoSitePlus	COSMIC	9.540	Down-regulation
Atypical_PIKK_ATM_ATM_ST	Q09472	EP300	Q13315	ATM	S106	Q107H	107	Missense	proximal	1	no	15.018	0.109	PhosphoSitePlus	COSMIC	9.540	Loss
Atypical_PIKK_ATM_ATM_ST	Q09472	EP300	Q13315	ATM	S106	M104I	104	Missense	proximal	-2	no	15.018	14.767	PhosphoSitePlus	COSMIC	9.540	Down-regulation
Atypical_PIKK_ATM_ATM_ST	Q09472	EP300	Q13315	ATM	T258	P252L	252	Missense	distal	-6	no	12.150	11.921	EPSD	COSMIC	9.540	Down-regulation
Atypical_PIKK_ATM_ATM_ST	Q09472	EP300	Q13315	ATM	T258	Q263E	263	Missense	distal	5	no	12.150	11.926	EPSD	COSMIC	9.540	Down-regulation
Atypical_PIKK_ATM_ATM_ST	Q09472	EP300	Q13315	ATM	T258	Y253C	253	Missense	distal	-5	no	12.150	12.219	EPSD	COSMIC	9.540	Up-regulation
Atypical_PIKK_ATM_ATM_ST	Q09472	EP300	Q13315	ATM	T258	P252S	252	Missense	distal	-6	no	12.150	12.209	EPSD	COSMIC	9.540	Up-regulation
Atypical_PIKK_ATM_ATM_ST	Q09472	EP300	Q13315	ATM	T258	S255L	255	Missense	distal	-3	no	12.150	12.359	EPSD	COSMIC	9.540	Up-regulation
Atypical_PIKK_ATM_ATM_ST	Q09472	EP300	Q13315	ATM	T258	Q264H	264	Missense	distal	6	no	12.150	12.139	EPSD	COSMIC	9.540	Down-regulation
Atypical_PIKK_ATM_ATM_ST	Q09472	EP300	Q13315	ATM	T258	P256S	256	Missense	proximal	-2	no	12.150	12.387	EPSD	COSMIC	9.540	Up-regulation
Atypical_PIKK_ATM_ATM_ST	Q09472	EP300	Q13315	ATM	S384	T380A	380	Missense	distal	-4	no	9.803	9.676	EPSD	COSMIC	9.540	Down-regulation
Atypical_PIKK_ATM_ATM_ST	Q09472	EP300	Q13315	ATM	S384	T380I	380	Missense	distal	-4	no	9.803	9.474	EPSD	COSMIC	9.540	Loss
Atypical_PIKK_ATM_ATM_ST	Q09472	EP300	Q13315	ATM	S384	C382Y	382	Missense	proximal	-2	no	9.803	10.095	EPSD	COSMIC	9.540	Up-regulation
Atypical_PIKK_ATM_ATM_ST	Q09472	EP300	Q13315	ATM	S396	R397Q	397	Missense	proximal	1	no	7.590	14.241	EPSD	COSMIC	9.540	Gain
Atypical_PIKK_ATM_ATM_ST	Q09472	EP300	Q13315	ATM	S831	L827P	827	Missense	distal	-4	no	9.885	10.155	EPSD	COSMIC	9.540	Up-regulation
Atypical_PIKK_ATM_ATM_ST	Q09472	EP300	Q13315	ATM	S831	R838S	838	Missense	distal	7	no	9.885	9.851	EPSD	COSMIC	9.540	Down-regulation
Atypical_PIKK_ATM_ATM_ST	Q09472	EP300	Q13315	ATM	T891	T890P	890	Missense	proximal	-1	no	10.398	10.095	EPSD	COSMIC	9.540	Down-regulation
Atypical_PIKK_ATM_ATM_ST	Q09472	EP300	Q13315	ATM	T891	P894S	894	Missense	distal	3	no	10.398	10.246	EPSD	COSMIC	9.540	Down-regulation
Atypical_PIKK_ATM_ATM_ST	Q09472	EP300	Q13315	ATM	T891	T891P	891	Missense	central	0	yes	10.398	0.000	EPSD	COSMIC;CCLE	9.540	Loss
Atypical_PIKK_ATM_ATM_ST	Q09472	EP300	Q13315	ATM	T992	A990T	990	Missense	proximal	-2	no	12.510	12.610	EPSD	COSMIC	9.540	Up-regulation
Atypical_PIKK_ATM_ATM_ST	Q09472	EP300	Q13315	ATM	T992	T992A	992	Missense	central	0	yes	12.510	0.000	EPSD	COSMIC	9.540	Loss
Atypical_PIKK_ATM_ATM_ST	Q09472	EP300	Q13315	ATM	T992	Q993R	993	Missense	proximal	1	no	12.510	5.858	EPSD	COSMIC	9.540	Loss
Atypical_PIKK_ATM_ATM_ST	Q09472	EP300	Q13315	ATM	T992	E988K	988	Missense	distal	-4	no	12.510	11.538	EPSD	COSMIC	9.540	Down-regulation
Atypical_PIKK_ATM_ATM_ST	Q09472	EP300	Q13315	ATM	T1012	E1013Q	1013	Missense	proximal	1	no	9.427	15.324	EPSD	COSMIC	9.540	Gain
Atypical_PIKK_ATM_ATM_ST	Q09472	EP300	Q13315	ATM	S1033	S1037L	1037	Missense	distal	4	no	9.231	9.573	EPSD	COSMIC	9.540	Gain
Atypical_PIKK_ATM_ATM_ST	Q09472	EP300	Q13315	ATM	T1035	S1037L	1037	Missense	proximal	2	no	14.535	13.291	EPSD	COSMIC	9.540	Down-regulation
Atypical_PIKK_ATM_ATM_ST	Q09472	EP300	Q13315	ATM	T1035	G1042R	1042	Missense	distal	7	no	14.535	14.528	EPSD	COSMIC	9.540	Down-regulation
Atypical_PIKK_ATM_ATM_ST	Q09472	EP300	Q13315	ATM	T1035	D1028N	1028	Missense	distal	-7	no	14.535	14.571	EPSD	COSMIC	9.540	Up-regulation
Atypical_PIKK_ATM_ATM_ST	Q09472	EP300	Q13315	ATM	S1038	S1037L	1037	Missense	proximal	-1	no	11.552	11.417	EPSD	COSMIC	9.540	Down-regulation
Atypical_PIKK_ATM_ATM_ST	Q09472	EP300	Q13315	ATM	S1038	G1042R	1042	Missense	distal	4	no	11.552	11.605	EPSD	COSMIC	9.540	Up-regulation
Atypical_PIKK_ATM_ATM_ST	Q09472	EP300	Q13315	ATM	S1220	V1213F	1213	Missense	distal	-7	no	15.159	14.810	EPSD	COSMIC	9.540	Down-regulation
Atypical_PIKK_ATM_ATM_ST	Q09472	EP300	Q13315	ATM	S1220	D1218N	1218	Missense	proximal	-2	no	15.159	15.278	EPSD	COSMIC	9.540	Up-regulation
Atypical_PIKK_ATM_ATM_ST	Q09472	EP300	Q13315	ATM	S1220	I1226L	1226	Missense	distal	6	no	15.159	15.143	EPSD	COSMIC	9.540	Down-regulation
Atypical_PIKK_ATM_ATM_ST	Q09472	EP300	Q13315	ATM	S1220	Q1221H	1221	Missense	proximal	1	no	15.159	0.250	EPSD	COSMIC	9.540	Loss
Atypical_PIKK_ATM_ATM_ST	Q09472	EP300	Q13315	ATM	S1220	D1217N	1217	Missense	distal	-3	no	15.159	14.886	EPSD	COSMIC	9.540	Down-regulation
Atypical_PIKK_ATM_ATM_ST	Q09472	EP300	Q13315	ATM	S1220	S1220C	1220	Missense	central	0	yes	15.159	0.000	EPSD	COSMIC	9.540	Loss
Atypical_PIKK_ATM_ATM_ST	Q09472	EP300	Q13315	ATM	S1220	T1224I	1224	Missense	distal	4	no	15.159	15.734	EPSD	COSMIC	9.540	Up-regulation
Atypical_PIKK_ATM_ATM_ST	Q09472	EP300	Q13315	ATM	T1225	I1226L	1226	Missense	proximal	1	no	-0.624	9.746	EPSD	COSMIC	9.540	Gain
Atypical_PIKK_ATM_ATM_ST	Q09472	EP300	Q13315	ATM	S1581	L1584R	1584	Missense	distal	3	no	14.540	14.444	EPSD	COSMIC;CCLE	9.540	Down-regulation
Atypical_PIKK_ATM_ATM_ST	Q09472	EP300	Q13315	ATM	S1581	L1580P	1580	Missense	proximal	-1	no	14.540	14.383	EPSD	COSMIC	9.540	Down-regulation
Atypical_PIKK_ATM_ATM_ST	Q09472	EP300	Q13315	ATM	S1581	N1575S	1575	Missense	distal	-6	no	14.540	14.656	EPSD	COSMIC	9.540	Up-regulation
Atypical_PIKK_ATM_ATM_ST	Q09472	EP300	Q13315	ATM	S1581	D1579N	1579	Missense	proximal	-2	no	14.540	14.659	EPSD	COSMIC	9.540	Up-regulation
Atypical_PIKK_ATM_ATM_ST	Q09472	EP300	Q13315	ATM	T1724	S1730Y	1730	Missense	distal	6	no	13.479	13.437	EPSD	COSMIC	9.540	Down-regulation
Atypical_PIKK_ATM_ATM_ST	Q09472	EP300	Q13315	ATM	T1724	S1730F	1730	Missense	distal	6	no	13.479	13.403	EPSD	COSMIC	9.540	Down-regulation
Atypical_PIKK_ATM_ATM_ST	Q09472	EP300	Q13315	ATM	S1726	S1730F	1730	Missense	distal	4	no	8.815	9.643	EPSD	COSMIC	9.540	Gain
Atypical_PIKK_ATM_ATM_ST	Q09472	EP300	Q13315	ATM	S1849	G1842E	1842	Missense	distal	-7	no	9.107	9.975	EPSD	COSMIC	9.540	Gain
Atypical_PIKK_ATM_ATM_ST	Q09472	EP300	Q13315	ATM	S1897	S1897F	1897	Missense	central	0	yes	12.874	0.000	EPSD	COSMIC	9.540	Loss
Atypical_PIKK_ATM_ATM_ST	Q09472	EP300	Q13315	ATM	S1897	G1899D	1899	Missense	proximal	2	no	12.874	14.112	EPSD	COSMIC	9.540	Up-regulation
Atypical_PIKK_ATM_ATM_ST	Q09472	EP300	Q13315	ATM	S2320	H2324T	2324	Missense	distal	4	no	14.307	14.277	EPSD	COSMIC	9.540	Down-regulation
Atypical_PIKK_ATM_ATM_ST	Q09472	EP300	Q13315	ATM	S2320	P2314T	2314	Missense	distal	-6	no	14.307	14.297	EPSD	COSMIC	9.540	Down-regulation
Atypical_PIKK_ATM_ATM_ST	Q09472	EP300	Q13315	ATM	S2320	R2317W	2317	Missense	distal	-3	no	14.307	13.878	EPSD	COSMIC	9.540	Down-regulation
Atypical_PIKK_ATM_ATM_ST	Q09472	EP300	Q13315	ATM	S2320	H2324Y	2324	Missense	distal	4	no	14.307	14.492	EPSD	COSMIC	9.540	Up-regulation
Atypical_PIKK_ATM_ATM_ST	Q09472	EP300	Q13315	ATM	S2326	H2324T	2324	Missense	proximal	-2	no	9.413	9.752	EPSD	COSMIC	9.540	Gain
Atypical_PIKK_ATM_ATM_ST	Q09472	EP300	Q13315	ATM	S2326	H2324Y	2324	Missense	proximal	-2	no	9.413	9.670	EPSD	COSMIC	9.540	Gain
Atypical_PIKK_ATM_ATM_ST	Q92878	RAD50	Q13315	ATM	T198	R193W	193	Missense	distal	-5	no	11.334	11.499	EPSD	COSMIC	9.540	Up-regulation
Atypical_PIKK_ATM_ATM_ST	Q92878	RAD50	Q13315	ATM	T198	R196L	196	Missense	proximal	-2	no	11.334	11.387	EPSD	COSMIC	9.540	Up-regulation
Atypical_PIKK_ATM_ATM_ST	Q92878	RAD50	Q13315	ATM	T198	V203L	203	Missense	distal	5	no	11.334	11.286	EPSD	COSMIC	9.540	Down-regulation
Atypical_PIKK_ATM_ATM_ST	Q92878	RAD50	Q13315	ATM	T198	T191I	191	Missense	distal	-7	no	11.334	10.750	EPSD	COSMIC	9.540	Down-regulation
Atypical_PIKK_ATM_ATM_ST	Q92878	RAD50	Q13315	ATM	T536	T536I	536	Missense	central	0	yes	11.201	0.000	EPSD	COSMIC	9.540	Loss
Atypical_PIKK_ATM_ATM_ST	Q92878	RAD50	Q13315	ATM	T536	T534K	534	Missense	proximal	-2	no	11.201	10.894	EPSD	COSMIC	9.540	Down-regulation
Atypical_PIKK_ATM_ATM_ST	Q92878	RAD50	Q13315	ATM	T536	L541P	541	Missense	distal	5	no	11.201	11.218	EPSD	COSMIC	9.540	Up-regulation
Atypical_PIKK_ATM_ATM_ST	Q92878	RAD50	Q13315	ATM	S635	S635N	635	Missense	central	0	yes	14.965	0.000	PhosphoSitePlus	COSMIC	9.540	Loss
Atypical_PIKK_ATM_ATM_ST	Q92878	RAD50	Q13315	ATM	S635	K628M	628	Missense	distal	-7	no	14.965	14.803	PhosphoSitePlus	COSMIC	9.540	Down-regulation
Atypical_PIKK_ATM_ATM_ST	Q92878	RAD50	Q13315	ATM	S635	L629Q	629	Missense	distal	-6	no	14.965	15.217	PhosphoSitePlus	COSMIC	9.540	Up-regulation
Atypical_PIKK_ATM_ATM_ST	Q92878	RAD50	Q13315	ATM	S1297	V1304A	1304	Missense	distal	7	no	9.876	9.858	EPSD	COSMIC;GDSC;CCLE	9.540	Down-regulation
Atypical_PIKK_ATM_ATM_ST	Q92878	RAD50	Q13315	ATM	S1297	D1294N	1294	Missense	distal	-3	no	9.876	9.603	EPSD	COSMIC	9.540	Down-regulation
Atypical_PIKK_ATM_ATM_ST	Q92878	RAD50	Q13315	ATM	S1297	N1292S	1292	Missense	distal	-5	no	9.876	9.903	EPSD	COSMIC	9.540	Up-regulation
Atypical_PIKK_ATM_ATM_ST	Q13263	TRIM28	Q13315	ATM	S440	V445M	445	Missense	distal	5	no	14.621	14.594	EPSD	COSMIC	9.540	Down-regulation
Atypical_PIKK_ATM_ATM_ST	Q13263	TRIM28	Q13315	ATM	S440	S437F	437	Missense	distal	-3	no	14.621	15.693	EPSD	COSMIC	9.540	Up-regulation
Atypical_PIKK_ATM_ATM_ST	Q13263	TRIM28	Q13315	ATM	S440	P442L	442	Missense	proximal	2	no	14.621	13.832	EPSD	COSMIC;GDSC	9.540	Down-regulation
Atypical_PIKK_ATM_ATM_ST	Q13263	TRIM28	Q13315	ATM	S460	G467D	467	Missense	distal	7	no	10.071	10.039	EPSD	COSMIC	9.540	Down-regulation
Atypical_PIKK_ATM_ATM_ST	Q13263	TRIM28	Q13315	ATM	S501	D500H	500	Missense	proximal	-1	no	14.167	14.017	EPSD	COSMIC	9.540	Down-regulation
Atypical_PIKK_ATM_ATM_ST	Q13263	TRIM28	Q13315	ATM	S594	R591L	591	Missense	distal	-3	no	10.834	10.303	EPSD	COSMIC	9.540	Down-regulation
Atypical_PIKK_ATM_ATM_ST	Q13263	TRIM28	Q13315	ATM	S594	P590L	590	Missense	distal	-4	no	10.834	10.564	EPSD	COSMIC	9.540	Down-regulation
Atypical_PIKK_ATM_ATM_ST	Q13263	TRIM28	Q13315	ATM	S594	R591C	591	Missense	distal	-3	no	10.834	10.262	EPSD	COSMIC	9.540	Down-regulation
Atypical_PIKK_ATM_ATM_ST	Q13263	TRIM28	Q13315	ATM	T620	G616S	616	Missense	distal	-4	no	9.300	10.089	EPSD	COSMIC	9.540	Gain
Atypical_PIKK_ATM_ATM_ST	Q13263	TRIM28	Q13315	ATM	S624	A625P	625	Missense	proximal	1	no	9.022	11.094	EPSD	COSMIC	9.540	Gain
Atypical_PIKK_ATM_ATM_ST	Q13263	TRIM28	Q13315	ATM	S757	P753H	753	Missense	distal	-4	no	9.585	9.574	EPSD	COSMIC	9.540	Down-regulation
Atypical_PIKK_ATM_ATM_ST	Q13263	TRIM28	Q13315	ATM	S824	G830D	830	Missense	distal	6	no	15.344	15.341	PhosphoSitePlus	COSMIC	9.540	Down-regulation
Atypical_PIKK_ATM_ATM_ST	Q13263	TRIM28	Q13315	ATM	S828	G830D	830	Missense	proximal	2	no	9.840	11.078	EPSD	COSMIC	9.540	Up-regulation
Atypical_PIKK_ATM_ATM_ST	Q15910	EZH2	Q13315	ATM	S212	R207W	207	Missense	distal	-5	no	10.255	10.420	EPSD	COSMIC	9.540	Up-regulation
Atypical_PIKK_ATM_ATM_ST	Q15910	EZH2	Q13315	ATM	S212	R213H	213	Missense	proximal	1	no	10.255	1.997	EPSD	COSMIC	9.540	Loss
Atypical_PIKK_ATM_ATM_ST	Q15910	EZH2	Q13315	ATM	S212	R213C	213	Missense	proximal	1	no	10.255	4.696	EPSD	COSMIC	9.540	Loss
Atypical_PIKK_ATM_ATM_ST	Q15910	EZH2	Q13315	ATM	S212	K210E	210	Missense	proximal	-2	no	10.255	10.830	EPSD	COSMIC	9.540	Up-regulation
Atypical_PIKK_ATM_ATM_ST	Q15910	EZH2	Q13315	ATM	S212	P219S	219	Missense	distal	7	no	10.255	10.236	EPSD	COSMIC;GDSC;CCLE	9.540	Down-regulation
Atypical_PIKK_ATM_ATM_ST	Q15910	EZH2	Q13315	ATM	S212	P215S	215	Missense	distal	3	no	10.255	10.103	EPSD	COSMIC;GDSC	9.540	Down-regulation
Atypical_PIKK_ATM_ATM_ST	Q15910	EZH2	Q13315	ATM	S212	R216W	216	Missense	distal	4	no	10.255	10.399	EPSD	COSMIC	9.540	Up-regulation
Atypical_PIKK_ATM_ATM_ST	Q15910	EZH2	Q13315	ATM	S212	H206Q	206	Missense	distal	-6	no	10.255	10.397	EPSD	COSMIC	9.540	Up-regulation
Atypical_PIKK_ATM_ATM_ST	Q15910	EZH2	Q13315	ATM	S277	S271C	271	Missense	distal	-6	no	9.721	9.342	EPSD	COSMIC	9.540	Loss
Atypical_PIKK_ATM_ATM_ST	Q15910	EZH2	Q13315	ATM	S277	H279Q	279	Missense	proximal	2	no	9.721	10.101	EPSD	COSMIC	9.540	Up-regulation
Atypical_PIKK_ATM_ATM_ST	Q15910	EZH2	Q13315	ATM	S277	H282Y	282	Missense	distal	5	no	9.721	9.647	EPSD	COSMIC	9.540	Down-regulation
Atypical_PIKK_ATM_ATM_ST	Q15910	EZH2	Q13315	ATM	S277	T283M	283	Missense	distal	6	no	9.721	9.702	EPSD	COSMIC	9.540	Down-regulation
Atypical_PIKK_ATM_ATM_ST	Q15910	EZH2	Q13315	ATM	S277	H279Y	279	Missense	proximal	2	no	9.721	9.542	EPSD	COSMIC;GDSC;CCLE	9.540	Down-regulation
Atypical_PIKK_ATM_ATM_ST	Q15910	EZH2	Q13315	ATM	S277	S280C	280	Missense	distal	3	no	9.721	10.143	EPSD	COSMIC	9.540	Up-regulation
Atypical_PIKK_ATM_ATM_ST	Q15910	EZH2	Q13315	ATM	S375	P368S	368	Missense	distal	-7	no	9.466	9.702	EPSD	COSMIC	9.540	Gain
Atypical_PIKK_ATM_ATM_ST	Q15910	EZH2	Q13315	ATM	S408	R413W	413	Missense	distal	5	no	9.544	9.568	EPSD	COSMIC	9.540	Up-regulation
Atypical_PIKK_ATM_ATM_ST	Q15910	EZH2	Q13315	ATM	S408	S405L	405	Missense	distal	-3	no	9.544	9.753	EPSD	COSMIC	9.540	Up-regulation
Atypical_PIKK_ATM_ATM_ST	Q15910	EZH2	Q13315	ATM	S408	E409K	409	Missense	proximal	1	no	9.544	8.593	EPSD	COSMIC	9.540	Loss
Atypical_PIKK_ATM_ATM_ST	Q15910	EZH2	Q13315	ATM	S408	S408F	408	Missense	central	0	yes	9.544	0.000	EPSD	COSMIC	9.540	Loss
Atypical_PIKK_ATM_ATM_ST	Q15910	EZH2	Q13315	ATM	S408	S412F	412	Missense	distal	4	no	9.544	10.372	EPSD	COSMIC	9.540	Up-regulation
Atypical_PIKK_ATM_ATM_ST	Q15910	EZH2	Q13315	ATM	S408	Q415E	415	Missense	distal	7	no	9.544	9.530	EPSD	COSMIC	9.540	Loss
Atypical_PIKK_ATM_ATM_ST	Q15910	EZH2	Q13315	ATM	S408	R413Q	413	Missense	distal	5	no	9.544	9.432	EPSD	COSMIC;CCLE	9.540	Loss
Atypical_PIKK_ATM_ATM_ST	Q15910	EZH2	Q13315	ATM	S412	R413Q	413	Missense	proximal	1	no	8.198	14.849	EPSD	COSMIC;CCLE	9.540	Gain
Atypical_PIKK_ATM_ATM_ST	Q15910	EZH2	Q13315	ATM	T416	Q415E	415	Missense	proximal	-1	no	9.480	9.757	EPSD	COSMIC	9.540	Gain
Atypical_PIKK_ATM_ATM_ST	Q15910	EZH2	Q13315	ATM	T416	P417Q	417	Missense	proximal	1	no	9.480	14.282	EPSD	COSMIC	9.540	Gain
Atypical_PIKK_ATM_ATM_ST	Q15910	EZH2	Q13315	ATM	S647	Q648E	648	Missense	proximal	1	no	18.239	12.342	EPSD	COSMIC	9.540	Down-regulation
Atypical_PIKK_ATM_ATM_ST	Q15910	EZH2	Q13315	ATM	S647	G643E	643	Missense	distal	-4	no	18.239	19.306	EPSD	COSMIC;CCLE	9.540	Up-regulation
Atypical_PIKK_ATM_ATM_ST	Q15910	EZH2	Q13315	ATM	S647	S647F	647	Missense	central	0	yes	18.239	0.000	EPSD	COSMIC	9.540	Loss
Atypical_PIKK_ATM_ATM_ST	Q15910	EZH2	Q13315	ATM	S647	S647C	647	Missense	central	0	yes	18.239	0.000	EPSD	COSMIC	9.540	Loss
Atypical_PIKK_ATM_ATM_ST	Q15910	EZH2	Q13315	ATM	S647	G643V	643	Missense	distal	-4	no	18.239	18.038	EPSD	COSMIC	9.540	Down-regulation
Atypical_PIKK_ATM_ATM_ST	Q15910	EZH2	Q13315	ATM	S647	D652G	652	Missense	distal	5	no	18.239	18.331	EPSD	COSMIC	9.540	Up-regulation
Atypical_PIKK_ATM_ATM_ST	Q15910	EZH2	Q13315	ATM	S647	A651V	651	Missense	distal	4	no	18.239	18.892	EPSD	COSMIC	9.540	Up-regulation
Atypical_PIKK_ATM_ATM_ST	Q15910	EZH2	Q13315	ATM	S647	E650G	650	Missense	distal	3	no	18.239	18.545	EPSD	COSMIC	9.540	Up-regulation
Atypical_PIKK_ATM_ATM_ST	Q15910	EZH2	Q13315	ATM	S647	E640K	640	Missense	distal	-7	no	18.239	17.571	EPSD	COSMIC	9.540	Down-regulation
Atypical_PIKK_ATM_ATM_ST	Q15910	EZH2	Q13315	ATM	S647	G643R	643	Missense	distal	-4	no	18.239	18.217	EPSD	COSMIC	9.540	Down-regulation
Atypical_PIKK_ATM_ATM_ST	Q15910	EZH2	Q13315	ATM	S647	E650Q	650	Missense	distal	3	no	18.239	18.498	EPSD	COSMIC	9.540	Up-regulation
Atypical_PIKK_ATM_ATM_ST	Q15910	EZH2	Q13315	ATM	S647	A651D	651	Missense	distal	4	no	18.239	18.794	EPSD	COSMIC	9.540	Up-regulation
Atypical_PIKK_ATM_ATM_ST	Q15910	EZH2	Q13315	ATM	S647	Y641D	641	Missense	distal	-6	no	18.239	18.461	EPSD	COSMIC	9.540	Up-regulation
Atypical_PIKK_ATM_ATM_ST	Q15910	EZH2	Q13315	ATM	S647	R654K	654	Missense	distal	7	no	18.239	18.227	EPSD	COSMIC	9.540	Down-regulation
Atypical_PIKK_ATM_ATM_ST	Q15910	EZH2	Q13315	ATM	S647	Q648K	648	Missense	proximal	1	no	18.239	11.391	EPSD	COSMIC	9.540	Down-regulation
Atypical_PIKK_ATM_ATM_ST	Q15910	EZH2	Q13315	ATM	S647	I645S	645	Missense	proximal	-2	no	18.239	18.929	EPSD	COSMIC	9.540	Up-regulation
Atypical_PIKK_ATM_ATM_ST	Q15910	EZH2	Q13315	ATM	S729	Y728H	728	Missense	proximal	-1	no	14.605	14.449	EPSD	COSMIC	9.540	Down-regulation
Atypical_PIKK_ATM_ATM_ST	Q15910	EZH2	Q13315	ATM	S729	Y726H	726	Missense	distal	-3	no	14.605	14.567	EPSD	COSMIC	9.540	Down-regulation
Atypical_PIKK_ATM_ATM_ST	Q15910	EZH2	Q13315	ATM	S729	Y726N	726	Missense	distal	-3	no	14.605	14.445	EPSD	COSMIC	9.540	Down-regulation
Atypical_PIKK_ATM_ATM_ST	Q15910	EZH2	Q13315	ATM	S729	F724S	724	Missense	distal	-5	no	14.605	14.282	EPSD	COSMIC	9.540	Down-regulation
Atypical_PIKK_ATM_ATM_ST	Q15910	EZH2	Q13315	ATM	S729	D725Y	725	Missense	distal	-4	no	14.605	13.509	EPSD	COSMIC	9.540	Down-regulation
Atypical_PIKK_ATM_ATM_ST	Q15910	EZH2	Q13315	ATM	S729	Y726D	726	Missense	distal	-3	no	14.605	14.718	EPSD	COSMIC	9.540	Up-regulation
Atypical_PIKK_ATM_ATM_ST	Q15910	EZH2	Q13315	ATM	S729	S729I	729	Missense	central	0	yes	14.605	0.000	EPSD	COSMIC	9.540	Loss
Atypical_PIKK_ATM_ATM_ST	Q15910	EZH2	Q13315	ATM	S729	Y726C	726	Missense	distal	-3	no	14.605	14.640	EPSD	COSMIC	9.540	Up-regulation
Atypical_PIKK_ATM_ATM_ST	Q15910	EZH2	Q13315	ATM	S729	R727I	727	Missense	proximal	-2	no	14.605	14.358	EPSD	COSMIC	9.540	Down-regulation
Atypical_PIKK_ATM_ATM_ST	Q9NZM5	NOP53	Q13315	ATM	S233	H229Q	229	Missense	distal	-4	no	15.156	15.390	EPSD;PhosphoSitePlus	COSMIC	9.540	Up-regulation
Atypical_PIKK_ATM_ATM_ST	Q9NZM5	NOP53	Q13315	ATM	S233	R227C	227	Missense	distal	-6	no	15.156	14.956	EPSD;PhosphoSitePlus	COSMIC;GDSC	9.540	Down-regulation
Atypical_PIKK_ATM_ATM_ST	Q9NZM5	NOP53	Q13315	ATM	S233	K231R	231	Missense	proximal	-2	no	15.156	15.108	EPSD;PhosphoSitePlus	COSMIC	9.540	Down-regulation
Atypical_PIKK_ATM_ATM_ST	Q9NZM5	NOP53	Q13315	ATM	S233	P232S	232	Missense	proximal	-1	no	15.156	15.448	EPSD;PhosphoSitePlus	COSMIC	9.540	Up-regulation
Atypical_PIKK_ATM_ATM_ST	Q9NZM5	NOP53	Q13315	ATM	S233	A237T	237	Missense	distal	4	no	15.156	15.591	EPSD;PhosphoSitePlus	COSMIC	9.540	Up-regulation
Atypical_PIKK_ATM_ATM_ST	Q9NZM5	NOP53	Q13315	ATM	S233	V238M	238	Missense	distal	5	no	15.156	15.128	EPSD;PhosphoSitePlus	COSMIC	9.540	Down-regulation
Atypical_PIKK_ATM_ATM_ST	Q9NZM5	NOP53	Q13315	ATM	S233	P232L	232	Missense	proximal	-1	no	15.156	15.313	EPSD;PhosphoSitePlus	COSMIC	9.540	Up-regulation
Atypical_PIKK_ATM_ATM_ST	Q9NZM5	NOP53	Q13315	ATM	T289	T284R	284	Missense	distal	-5	no	14.899	15.064	PhosphoSitePlus;EPSD	COSMIC	9.540	Up-regulation
Atypical_PIKK_ATM_ATM_ST	Q9NZM5	NOP53	Q13315	ATM	T289	T284M	284	Missense	distal	-5	no	14.899	15.072	PhosphoSitePlus;EPSD	COSMIC	9.540	Up-regulation
Atypical_PIKK_ATM_ATM_ST	O15151	MDM4	Q13315	ATM	S20	S20C	20	Missense	central	0	yes	11.562	0.000	EPSD	COSMIC	9.540	Loss
Atypical_PIKK_ATM_ATM_ST	O15151	MDM4	Q13315	ATM	S20	S15R	15	Missense	distal	-5	no	11.562	11.638	EPSD	COSMIC	9.540	Up-regulation
Atypical_PIKK_ATM_ATM_ST	O15151	MDM4	Q13315	ATM	S20	I24M	24	Missense	distal	4	no	11.562	11.160	EPSD	COSMIC	9.540	Down-regulation
Atypical_PIKK_ATM_ATM_ST	O15151	MDM4	Q13315	ATM	S20	P21S	21	Missense	proximal	1	no	11.562	4.587	EPSD	COSMIC	9.540	Loss
Atypical_PIKK_ATM_ATM_ST	O15151	MDM4	Q13315	ATM	S20	D14H	14	Missense	distal	-6	no	11.562	11.410	EPSD	COSMIC	9.540	Down-regulation
Atypical_PIKK_ATM_ATM_ST	O15151	MDM4	Q13315	ATM	S161	E162Q	162	Missense	proximal	1	no	8.386	14.283	EPSD	COSMIC	9.540	Gain
Atypical_PIKK_ATM_ATM_ST	O15151	MDM4	Q13315	ATM	S264	G268E	268	Missense	distal	4	no	12.206	11.779	EPSD	COSMIC	9.540	Down-regulation
Atypical_PIKK_ATM_ATM_ST	O15151	MDM4	Q13315	ATM	S264	V267A	267	Missense	distal	3	no	12.206	11.918	EPSD	COSMIC;GDSC;CCLE	9.540	Down-regulation
Atypical_PIKK_ATM_ATM_ST	O15151	MDM4	Q13315	ATM	S264	D259N	259	Missense	distal	-5	no	12.206	12.389	EPSD	COSMIC	9.540	Up-regulation
Atypical_PIKK_ATM_ATM_ST	O15151	MDM4	Q13315	ATM	S291	V296I	296	Missense	distal	5	no	9.939	9.937	EPSD	COSMIC	9.540	Down-regulation
Atypical_PIKK_ATM_ATM_ST	O15151	MDM4	Q13315	ATM	S291	L284P	284	Missense	distal	-7	no	9.939	10.291	EPSD	COSMIC	9.540	Up-regulation
Atypical_PIKK_ATM_ATM_ST	O15151	MDM4	Q13315	ATM	S291	V298G	298	Missense	distal	7	no	9.939	9.932	EPSD	COSMIC	9.540	Down-regulation
Atypical_PIKK_ATM_ATM_ST	O15151	MDM4	Q13315	ATM	S291	E297D	297	Missense	distal	6	no	9.939	9.893	EPSD	COSMIC;GDSC;CCLE	9.540	Down-regulation
Atypical_PIKK_ATM_ATM_ST	O15151	MDM4	Q13315	ATM	S291	D286N	286	Missense	distal	-5	no	9.939	10.122	EPSD	COSMIC	9.540	Up-regulation
Atypical_PIKK_ATM_ATM_ST	O15151	MDM4	Q13315	ATM	S291	S289F	289	Missense	proximal	-2	no	9.939	9.039	EPSD	COSMIC	9.540	Loss
Atypical_PIKK_ATM_ATM_ST	O15151	MDM4	Q13315	ATM	S344	L337V	337	Missense	distal	-7	no	10.085	10.192	EPSD	COSMIC	9.540	Up-regulation
Atypical_PIKK_ATM_ATM_ST	O15151	MDM4	Q13315	ATM	S344	S342F	342	Missense	proximal	-2	no	10.085	9.185	EPSD	COSMIC	9.540	Loss
Atypical_PIKK_ATM_ATM_ST	O15151	MDM4	Q13315	ATM	S403	S409R	409	Missense	distal	6	no	15.294	15.277	PhosphoSitePlus	COSMIC	9.540	Down-regulation
Atypical_PIKK_ATM_ATM_ST	O15151	MDM4	Q13315	ATM	S403	I407N	407	Missense	distal	4	no	15.294	14.759	PhosphoSitePlus	COSMIC	9.540	Down-regulation
Atypical_PIKK_ATM_ATM_ST	O15151	MDM4	Q13315	ATM	S403	S408L	408	Missense	distal	5	no	15.294	15.459	PhosphoSitePlus	COSMIC	9.540	Up-regulation
Atypical_PIKK_ATM_ATM_ST	O15151	MDM4	Q13315	ATM	S403	I407L	407	Missense	distal	4	no	15.294	14.973	PhosphoSitePlus	COSMIC	9.540	Down-regulation
Atypical_PIKK_ATM_ATM_ST	O15151	MDM4	Q13315	ATM	S403	H399Y	399	Missense	distal	-4	no	15.294	14.873	PhosphoSitePlus	COSMIC	9.540	Down-regulation
Atypical_PIKK_ATM_ATM_ST	Q9H9Q4	NHEJ1	Q13315	ATM	S55	V49G	49	Missense	distal	-6	no	12.475	12.529	EPSD	COSMIC	9.540	Up-regulation
Atypical_PIKK_ATM_ATM_ST	Q9H9Q4	NHEJ1	Q13315	ATM	S55	R57L	57	Missense	proximal	2	no	12.475	12.228	EPSD	COSMIC	9.540	Down-regulation
Atypical_PIKK_ATM_ATM_ST	Q9H9Q4	NHEJ1	Q13315	ATM	S55	V54A	54	Missense	proximal	-1	no	12.475	12.737	EPSD	COSMIC	9.540	Up-regulation
Atypical_PIKK_ATM_ATM_ST	Q9H9Q4	NHEJ1	Q13315	ATM	S132	R137C	137	Missense	distal	5	no	15.143	15.203	EPSD	COSMIC	9.540	Up-regulation
Atypical_PIKK_ATM_ATM_ST	Q9H9Q4	NHEJ1	Q13315	ATM	S251	Q256H	256	Missense	distal	5	no	13.629	13.716	PhosphoSitePlus	COSMIC	9.540	Up-regulation
Atypical_PIKK_ATM_ATM_ST	Q14191	WRN	Q13315	ATM	S248	N251Y	251	Missense	distal	3	no	9.686	9.728	EPSD	COSMIC	9.540	Up-regulation
Atypical_PIKK_ATM_ATM_ST	Q14191	WRN	Q13315	ATM	S409	I404N	404	Missense	distal	-5	no	15.058	14.916	EPSD	COSMIC	9.540	Down-regulation
Atypical_PIKK_ATM_ATM_ST	Q14191	WRN	Q13315	ATM	S409	E406K	406	Missense	distal	-3	no	15.058	15.125	EPSD	COSMIC	9.540	Up-regulation
Atypical_PIKK_ATM_ATM_ST	Q14191	WRN	Q13315	ATM	S440	E447K	447	Missense	distal	7	no	10.013	10.040	EPSD	COSMIC	9.540	Up-regulation
Atypical_PIKK_ATM_ATM_ST	Q14191	WRN	Q13315	ATM	S440	S440N	440	Missense	central	0	yes	10.013	0.000	EPSD	COSMIC	9.540	Loss
Atypical_PIKK_ATM_ATM_ST	Q14191	WRN	Q13315	ATM	S440	M446I	446	Missense	distal	6	no	10.013	10.001	EPSD	COSMIC;GDSC;CCLE	9.540	Down-regulation
Atypical_PIKK_ATM_ATM_ST	Q14191	WRN	Q13315	ATM	S440	D433N	433	Missense	distal	-7	no	10.013	10.049	EPSD	COSMIC	9.540	Up-regulation
Atypical_PIKK_ATM_ATM_ST	Q14191	WRN	Q13315	ATM	S453	E447K	447	Missense	distal	-6	no	9.647	9.346	EPSD	COSMIC	9.540	Loss
Atypical_PIKK_ATM_ATM_ST	Q14191	WRN	Q13315	ATM	S453	M446I	446	Missense	distal	-7	no	9.647	9.457	EPSD	COSMIC;GDSC;CCLE	9.540	Loss
Atypical_PIKK_ATM_ATM_ST	Q14191	WRN	Q13315	ATM	S453	N459K	459	Missense	distal	6	no	9.647	9.636	EPSD	COSMIC	9.540	Down-regulation
Atypical_PIKK_ATM_ATM_ST	Q14191	WRN	Q13315	ATM	S453	M448K	448	Missense	distal	-5	no	9.647	9.479	EPSD	COSMIC	9.540	Loss
Atypical_PIKK_ATM_ATM_ST	Q14191	WRN	Q13315	ATM	S478	M473I	473	Missense	distal	-5	no	10.713	10.742	EPSD	COSMIC;GDSC;CCLE	9.540	Up-regulation
Atypical_PIKK_ATM_ATM_ST	Q14191	WRN	Q13315	ATM	S478	S484N	484	Missense	distal	6	no	10.713	10.702	EPSD	COSMIC	9.540	Down-regulation
Atypical_PIKK_ATM_ATM_ST	Q14191	WRN	Q13315	ATM	S478	E480V	480	Missense	proximal	2	no	10.713	9.310	EPSD	COSMIC;GDSC;CCLE	9.540	Loss
Atypical_PIKK_ATM_ATM_ST	Q14191	WRN	Q13315	ATM	S790	C791G	791	Missense	proximal	1	no	4.187	9.924	EPSD	COSMIC	9.540	Gain
Atypical_PIKK_ATM_ATM_ST	Q14191	WRN	Q13315	ATM	S1058	Q1059E	1059	Missense	proximal	1	no	15.586	9.690	EPSD	COSMIC;GDSC;CCLE	9.540	Down-regulation
Atypical_PIKK_ATM_ATM_ST	Q14191	WRN	Q13315	ATM	S1099	T1100A	1100	Missense	proximal	1	no	7.830	10.765	EPSD	COSMIC	9.540	Gain
Atypical_PIKK_ATM_ATM_ST	Q14191	WRN	Q13315	ATM	S1111	K1117Q	1117	Missense	distal	6	no	10.259	10.258	EPSD	COSMIC	9.540	Down-regulation
Atypical_PIKK_ATM_ATM_ST	Q14191	WRN	Q13315	ATM	S1111	K1117M	1117	Missense	distal	6	no	10.259	10.251	EPSD	COSMIC	9.540	Down-regulation
Atypical_PIKK_ATM_ATM_ST	Q14191	WRN	Q13315	ATM	S1111	N1105D	1105	Missense	distal	-6	no	10.259	10.348	EPSD	COSMIC	9.540	Up-regulation
Atypical_PIKK_ATM_ATM_ST	Q14191	WRN	Q13315	ATM	S1133	A1137G	1137	Missense	distal	4	no	9.145	9.621	EPSD	COSMIC	9.540	Gain
Atypical_PIKK_ATM_ATM_ST	Q14191	WRN	Q13315	ATM	S1141	S1146L	1146	Missense	distal	5	no	16.725	16.889	PhosphoSitePlus	COSMIC	9.540	Up-regulation
Atypical_PIKK_ATM_ATM_ST	Q14191	WRN	Q13315	ATM	S1141	A1137G	1137	Missense	distal	-4	no	16.725	16.446	PhosphoSitePlus	COSMIC	9.540	Down-regulation
Atypical_PIKK_ATM_ATM_ST	Q14191	WRN	Q13315	ATM	S1141	A1147T	1147	Missense	distal	6	no	16.725	16.709	PhosphoSitePlus	COSMIC	9.540	Down-regulation
Atypical_PIKK_ATM_ATM_ST	Q14191	WRN	Q13315	ATM	S1378	P1376S	1376	Missense	proximal	-2	no	10.599	10.835	EPSD	COSMIC	9.540	Up-regulation
Atypical_PIKK_ATM_ATM_ST	Q14191	WRN	Q13315	ATM	S1378	G1377C	1377	Missense	proximal	-1	no	10.599	10.591	EPSD	COSMIC	9.540	Down-regulation
Atypical_PIKK_ATM_ATM_ST	Q14191	WRN	Q13315	ATM	S1378	S1385Y	1385	Missense	distal	7	no	10.599	10.633	EPSD	COSMIC	9.540	Up-regulation
Atypical_PIKK_ATM_ATM_ST	Q14191	WRN	Q13315	ATM	S1378	S1383L	1383	Missense	distal	5	no	10.599	10.763	EPSD	COSMIC	9.540	Up-regulation
Atypical_PIKK_ATM_ATM_ST	Q14191	WRN	Q13315	ATM	S1378	I1381M	1381	Missense	distal	3	no	10.599	10.353	EPSD	COSMIC	9.540	Down-regulation
Atypical_PIKK_ATM_ATM_ST	Q13362	PPP2R5C	Q13315	ATM	S360	L358V	358	Missense	proximal	-2	no	9.988	9.713	EPSD	COSMIC	9.540	Down-regulation
Atypical_PIKK_ATM_ATM_ST	Q13362	PPP2R5C	Q13315	ATM	S360	L358I	358	Missense	proximal	-2	no	9.988	9.688	EPSD	COSMIC	9.540	Down-regulation
Atypical_PIKK_ATM_ATM_ST	Q13362	PPP2R5C	Q13315	ATM	S520	R514M	514	Missense	distal	-6	no	14.823	14.758	PhosphoSitePlus	COSMIC	9.540	Down-regulation
Atypical_PIKK_ATM_ATM_ST	Q13362	PPP2R5C	Q13315	ATM	S520	E517Q	517	Missense	distal	-3	no	14.823	14.947	PhosphoSitePlus	COSMIC	9.540	Up-regulation
Atypical_PIKK_ATM_ATM_ST	Q13362	PPP2R5C	Q13315	ATM	S520	E517K	517	Missense	distal	-3	no	14.823	14.890	PhosphoSitePlus	COSMIC	9.540	Up-regulation
Atypical_PIKK_ATM_ATM_ST	Q13362	PPP2R5C	Q13315	ATM	S520	A515P	515	Missense	distal	-5	no	14.823	14.834	PhosphoSitePlus	COSMIC	9.540	Up-regulation
Atypical_PIKK_ATM_ATM_ST	Q14674	ESPL1	Q13315	ATM	S244	L249P	249	Missense	distal	5	no	10.020	10.037	EPSD	COSMIC	9.540	Up-regulation
Atypical_PIKK_ATM_ATM_ST	Q14674	ESPL1	Q13315	ATM	S244	P245L	245	Missense	proximal	1	no	10.020	8.465	EPSD	COSMIC	9.540	Loss
Atypical_PIKK_ATM_ATM_ST	Q14674	ESPL1	Q13315	ATM	S810	S816C	816	Missense	distal	6	no	9.715	9.643	EPSD	COSMIC	9.540	Down-regulation
Atypical_PIKK_ATM_ATM_ST	Q14674	ESPL1	Q13315	ATM	S810	G814C	814	Missense	distal	4	no	9.715	10.095	EPSD	COSMIC	9.540	Up-regulation
Atypical_PIKK_ATM_ATM_ST	Q14674	ESPL1	Q13315	ATM	S1308	P1303L	1303	Missense	distal	-5	no	9.678	9.697	EPSD	COSMIC	9.540	Up-regulation
Atypical_PIKK_ATM_ATM_ST	Q14674	ESPL1	Q13315	ATM	S1406	L1411M	1411	Missense	distal	5	no	9.671	9.692	EPSD	COSMIC	9.540	Up-regulation
Atypical_PIKK_ATM_ATM_ST	Q14674	ESPL1	Q13315	ATM	S1539	K1540E	1540	Missense	proximal	1	no	8.883	9.835	EPSD	COSMIC	9.540	Gain
Atypical_PIKK_ATM_ATM_ST	Q14674	ESPL1	Q13315	ATM	S1641	G1648R	1648	Missense	distal	7	no	9.708	9.702	EPSD	COSMIC	9.540	Down-regulation
Atypical_PIKK_ATM_ATM_ST	Q14674	ESPL1	Q13315	ATM	S1641	K1642N	1642	Missense	proximal	1	no	9.708	6.695	EPSD	COSMIC	9.540	Loss
Atypical_PIKK_ATM_ATM_ST	Q14674	ESPL1	Q13315	ATM	S2118	G2114S	2114	Missense	distal	-4	no	9.385	10.173	EPSD	COSMIC	9.540	Gain
Atypical_PIKK_ATM_ATM_ST	Q14674	ESPL1	Q13315	ATM	S2118	V2117A	2117	Missense	proximal	-1	no	9.385	9.648	EPSD	COSMIC	9.540	Gain
Atypical_PIKK_ATM_ATM_ST	Q9UER7	DAXX	Q13315	ATM	S33	A31V	31	Missense	proximal	-2	no	9.816	9.339	EPSD	COSMIC	9.540	Loss
Atypical_PIKK_ATM_ATM_ST	Q9UER7	DAXX	Q13315	ATM	S118	R119Q	119	Missense	proximal	1	no	9.024	15.676	EPSD	COSMIC	9.540	Gain
Atypical_PIKK_ATM_ATM_ST	Q9UER7	DAXX	Q13315	ATM	T162	H163Q	163	Missense	proximal	1	no	-2.753	12.156	EPSD	COSMIC	9.540	Gain
Atypical_PIKK_ATM_ATM_ST	Q9UER7	DAXX	Q13315	ATM	S176	Q177E	177	Missense	proximal	1	no	14.524	8.628	EPSD	COSMIC	9.540	Loss
Atypical_PIKK_ATM_ATM_ST	Q9UER7	DAXX	Q13315	ATM	S415	S412F	412	Missense	distal	-3	no	8.954	10.026	EPSD	COSMIC	9.540	Gain
Atypical_PIKK_ATM_ATM_ST	Q9UER7	DAXX	Q13315	ATM	S424	A423T	423	Missense	proximal	-1	no	15.255	15.426	EPSD	COSMIC	9.540	Up-regulation
Atypical_PIKK_ATM_ATM_ST	Q9UER7	DAXX	Q13315	ATM	S424	S429F	429	Missense	distal	5	no	15.255	15.561	EPSD	COSMIC	9.540	Up-regulation
Atypical_PIKK_ATM_ATM_ST	Q9UER7	DAXX	Q13315	ATM	S495	P496T	496	Missense	proximal	1	no	9.857	4.850	EPSD	COSMIC	9.540	Loss
Atypical_PIKK_ATM_ATM_ST	Q9UER7	DAXX	Q13315	ATM	S495	S498P	498	Missense	distal	3	no	9.857	10.009	EPSD	COSMIC	9.540	Up-regulation
Atypical_PIKK_ATM_ATM_ST	Q9UER7	DAXX	Q13315	ATM	S495	D491N	491	Missense	distal	-4	no	9.857	8.933	EPSD	COSMIC	9.540	Loss
Atypical_PIKK_ATM_ATM_ST	Q9UER7	DAXX	Q13315	ATM	S495	P496L	496	Missense	proximal	1	no	9.857	8.302	EPSD	COSMIC	9.540	Loss
Atypical_PIKK_ATM_ATM_ST	Q9UER7	DAXX	Q13315	ATM	S499	P496T	496	Missense	distal	-3	no	10.162	9.898	EPSD	COSMIC	9.540	Down-regulation
Atypical_PIKK_ATM_ATM_ST	Q9UER7	DAXX	Q13315	ATM	S499	S498P	498	Missense	proximal	-1	no	10.162	9.870	EPSD	COSMIC	9.540	Down-regulation
Atypical_PIKK_ATM_ATM_ST	Q9UER7	DAXX	Q13315	ATM	S499	P496L	496	Missense	distal	-3	no	10.162	10.175	EPSD	COSMIC	9.540	Up-regulation
Atypical_PIKK_ATM_ATM_ST	Q9UER7	DAXX	Q13315	ATM	S564	E560Q	560	Missense	distal	-4	no	13.924	13.201	PhosphoSitePlus	COSMIC	9.540	Down-regulation
Atypical_PIKK_ATM_ATM_ST	Q9UER7	DAXX	Q13315	ATM	S564	E568Q	568	Missense	distal	4	no	13.924	14.255	PhosphoSitePlus	COSMIC	9.540	Up-regulation
Atypical_PIKK_ATM_ATM_ST	Q9UER7	DAXX	Q13315	ATM	S564	F567S	567	Missense	distal	3	no	13.924	13.342	PhosphoSitePlus	COSMIC	9.540	Down-regulation
Atypical_PIKK_ATM_ATM_ST	Q9UER7	DAXX	Q13315	ATM	S564	E570D	570	Missense	distal	6	no	13.924	13.877	PhosphoSitePlus	COSMIC	9.540	Down-regulation
Atypical_PIKK_ATM_ATM_ST	Q9UER7	DAXX	Q13315	ATM	S564	L569V	569	Missense	distal	5	no	13.924	13.972	PhosphoSitePlus	COSMIC	9.540	Up-regulation
Atypical_PIKK_ATM_ATM_ST	Q9UER7	DAXX	Q13315	ATM	S564	E559K	559	Missense	distal	-5	no	13.924	14.006	PhosphoSitePlus	COSMIC	9.540	Up-regulation
Atypical_PIKK_ATM_ATM_ST	Q9UER7	DAXX	Q13315	ATM	S589	S593C	593	Missense	distal	4	no	9.235	9.744	EPSD	COSMIC	9.540	Gain
Atypical_PIKK_ATM_ATM_ST	Q9UER7	DAXX	Q13315	ATM	S593	S593C	593	Missense	central	0	yes	9.763	0.000	EPSD	COSMIC	9.540	Loss
Atypical_PIKK_ATM_ATM_ST	Q9UER7	DAXX	Q13315	ATM	S593	S593N	593	Missense	central	0	yes	9.763	0.000	EPSD	COSMIC	9.540	Loss
Atypical_PIKK_ATM_ATM_ST	Q9UER7	DAXX	Q13315	ATM	S593	S589F	589	Missense	distal	-4	no	9.763	8.364	EPSD	COSMIC	9.540	Loss
Atypical_PIKK_ATM_ATM_ST	Q9UER7	DAXX	Q13315	ATM	S593	P596L	596	Missense	distal	3	no	9.763	9.893	EPSD	COSMIC	9.540	Up-regulation
Atypical_PIKK_ATM_ATM_ST	Q9UER7	DAXX	Q13315	ATM	S618	H620Q	620	Missense	proximal	2	no	9.733	10.112	EPSD	COSMIC	9.540	Up-regulation
Atypical_PIKK_ATM_ATM_ST	Q9UER7	DAXX	Q13315	ATM	S618	P619S	619	Missense	proximal	1	no	9.733	2.757	EPSD	COSMIC	9.540	Loss
Atypical_PIKK_ATM_ATM_ST	Q9UER7	DAXX	Q13315	ATM	S618	W622C	622	Missense	distal	4	no	9.733	9.916	EPSD	COSMIC	9.540	Up-regulation
Atypical_PIKK_ATM_ATM_ST	Q9UER7	DAXX	Q13315	ATM	S618	S612F	612	Missense	distal	-6	no	9.733	9.201	EPSD	COSMIC	9.540	Loss
Atypical_PIKK_ATM_ATM_ST	Q9UER7	DAXX	Q13315	ATM	S618	D624G	624	Missense	distal	6	no	9.733	9.736	EPSD	COSMIC	9.540	Up-regulation
Atypical_PIKK_ATM_ATM_ST	Q9UER7	DAXX	Q13315	ATM	S618	G623R	623	Missense	distal	5	no	9.733	9.720	EPSD	COSMIC	9.540	Down-regulation
Atypical_PIKK_ATM_ATM_ST	Q9UER7	DAXX	Q13315	ATM	S668	C664R	664	Missense	distal	-4	no	9.356	10.119	EPSD	COSMIC	9.540	Gain
Atypical_PIKK_ATM_ATM_ST	Q9UER7	DAXX	Q13315	ATM	S668	T665I	665	Missense	distal	-3	no	9.356	10.094	EPSD	COSMIC	9.540	Gain
Atypical_PIKK_ATM_ATM_ST	Q9UER7	DAXX	Q13315	ATM	S675	S675F	675	Missense	central	0	yes	11.103	0.000	EPSD	COSMIC	9.540	Loss
Atypical_PIKK_ATM_ATM_ST	Q9UER7	DAXX	Q13315	ATM	S675	A677V	677	Missense	proximal	2	no	11.103	10.794	EPSD	COSMIC	9.540	Down-regulation
Atypical_PIKK_ATM_ATM_ST	Q9UER7	DAXX	Q13315	ATM	S675	S668C	668	Missense	distal	-7	no	11.103	10.430	EPSD	COSMIC	9.540	Down-regulation
Atypical_PIKK_ATM_ATM_ST	Q9UER7	DAXX	Q13315	ATM	S675	S682F	682	Missense	distal	7	no	11.103	11.163	EPSD	COSMIC	9.540	Up-regulation
Atypical_PIKK_ATM_ATM_ST	Q9UER7	DAXX	Q13315	ATM	S675	S668N	668	Missense	distal	-7	no	11.103	10.917	EPSD	COSMIC	9.540	Down-regulation
Atypical_PIKK_ATM_ATM_ST	Q9UER7	DAXX	Q13315	ATM	S688	S688C	688	Missense	central	0	yes	9.994	0.000	EPSD	COSMIC	9.540	Loss
Atypical_PIKK_ATM_ATM_ST	Q9UER7	DAXX	Q13315	ATM	S688	S682F	682	Missense	distal	-6	no	9.994	9.462	EPSD	COSMIC	9.540	Loss
Atypical_PIKK_ATM_ATM_ST	Q9UER7	DAXX	Q13315	ATM	S707	R705W	705	Missense	proximal	-2	no	11.319	11.268	EPSD	COSMIC;GDSC;CCLE	9.540	Down-regulation
Atypical_PIKK_ATM_ATM_ST	Q9UER7	DAXX	Q13315	ATM	S707	H711Y	711	Missense	distal	4	no	11.319	11.505	EPSD	COSMIC	9.540	Up-regulation
Atypical_PIKK_ATM_ATM_ST	Q9UER7	DAXX	Q13315	ATM	S707	R705L	705	Missense	proximal	-2	no	11.319	11.372	EPSD	COSMIC	9.540	Up-regulation
Atypical_PIKK_ATM_ATM_ST	Q9UER7	DAXX	Q13315	ATM	S707	P703S	703	Missense	distal	-4	no	11.319	11.988	EPSD	COSMIC	9.540	Up-regulation
Atypical_PIKK_ATM_ATM_ST	Q9UER7	DAXX	Q13315	ATM	S712	R705W	705	Missense	distal	-7	no	13.456	13.266	EPSD	COSMIC;GDSC;CCLE	9.540	Down-regulation
Atypical_PIKK_ATM_ATM_ST	Q9UER7	DAXX	Q13315	ATM	S712	H711Y	711	Missense	proximal	-1	no	13.456	13.612	EPSD	COSMIC	9.540	Up-regulation
Atypical_PIKK_ATM_ATM_ST	Q9UER7	DAXX	Q13315	ATM	S712	R705L	705	Missense	distal	-7	no	13.456	13.267	EPSD	COSMIC	9.540	Down-regulation
Atypical_PIKK_ATM_ATM_ST	Q9UER7	DAXX	Q13315	ATM	S737	D738V	738	Missense	proximal	1	no	10.480	3.516	EPSD	COSMIC	9.540	Loss
Atypical_PIKK_ATM_ATM_ST	Q9UER7	DAXX	Q13315	ATM	S739	D738V	738	Missense	proximal	-1	no	10.772	10.402	EPSD	COSMIC	9.540	Down-regulation
Atypical_PIKK_ATM_ATM_ST	Q5UIP0	RIF1	Q13315	ATM	S111	N110D	110	Missense	proximal	-1	no	9.942	9.943	EPSD	COSMIC	9.540	Up-regulation
Atypical_PIKK_ATM_ATM_ST	Q5UIP0	RIF1	Q13315	ATM	S111	R116H	116	Missense	distal	5	no	9.942	9.917	EPSD	COSMIC	9.540	Down-regulation
Atypical_PIKK_ATM_ATM_ST	Q5UIP0	RIF1	Q13315	ATM	S111	N114S	114	Missense	distal	3	no	9.942	9.742	EPSD	COSMIC	9.540	Down-regulation
Atypical_PIKK_ATM_ATM_ST	Q5UIP0	RIF1	Q13315	ATM	S143	S139G	139	Missense	distal	-4	no	9.576	8.788	EPSD	COSMIC	9.540	Loss
Atypical_PIKK_ATM_ATM_ST	Q5UIP0	RIF1	Q13315	ATM	S402	G405V	405	Missense	distal	3	no	9.586	9.799	EPSD	COSMIC	9.540	Up-regulation
Atypical_PIKK_ATM_ATM_ST	Q5UIP0	RIF1	Q13315	ATM	S402	P403S	403	Missense	proximal	1	no	9.586	2.611	EPSD	COSMIC	9.540	Loss
Atypical_PIKK_ATM_ATM_ST	Q5UIP0	RIF1	Q13315	ATM	S467	S469F	469	Missense	proximal	2	no	12.329	10.851	EPSD	COSMIC	9.540	Down-regulation
Atypical_PIKK_ATM_ATM_ST	Q5UIP0	RIF1	Q13315	ATM	S1162	K1160N	1160	Missense	proximal	-2	no	11.945	12.161	EPSD	COSMIC	9.540	Up-regulation
Atypical_PIKK_ATM_ATM_ST	Q5UIP0	RIF1	Q13315	ATM	T1210	P1212S	1212	Missense	proximal	2	no	9.479	9.934	EPSD	COSMIC	9.540	Gain
Atypical_PIKK_ATM_ATM_ST	Q5UIP0	RIF1	Q13315	ATM	S1236	N1232S	1232	Missense	distal	-4	no	11.274	12.203	EPSD	COSMIC	9.540	Up-regulation
Atypical_PIKK_ATM_ATM_ST	Q5UIP0	RIF1	Q13315	ATM	S1238	N1232S	1232	Missense	distal	-6	no	11.402	11.518	EPSD	COSMIC	9.540	Up-regulation
Atypical_PIKK_ATM_ATM_ST	Q5UIP0	RIF1	Q13315	ATM	S1403	P1409L	1409	Missense	distal	6	no	14.271	14.225	EPSD	COSMIC	9.540	Down-regulation
Atypical_PIKK_ATM_ATM_ST	Q5UIP0	RIF1	Q13315	ATM	S1403	N1410S	1410	Missense	distal	7	no	14.271	14.256	EPSD	COSMIC	9.540	Down-regulation
Atypical_PIKK_ATM_ATM_ST	Q5UIP0	RIF1	Q13315	ATM	S1431	E1430G	1430	Missense	proximal	-1	no	13.958	13.556	EPSD	COSMIC;GDSC;CCLE	9.540	Down-regulation
Atypical_PIKK_ATM_ATM_ST	Q5UIP0	RIF1	Q13315	ATM	T1518	E1514A	1514	Missense	distal	-4	no	14.892	14.104	EPSD	COSMIC	9.540	Down-regulation
Atypical_PIKK_ATM_ATM_ST	Q5UIP0	RIF1	Q13315	ATM	S1542	Q1537K	1537	Missense	distal	-5	no	13.468	13.518	EPSD	COSMIC	9.540	Up-regulation
Atypical_PIKK_ATM_ATM_ST	Q5UIP0	RIF1	Q13315	ATM	S1542	Q1537H	1537	Missense	distal	-5	no	13.468	13.650	EPSD	COSMIC	9.540	Up-regulation
Atypical_PIKK_ATM_ATM_ST	Q5UIP0	RIF1	Q13315	ATM	S1554	S1554Y	1554	Missense	central	0	yes	9.723	0.000	EPSD	COSMIC	9.540	Loss
Atypical_PIKK_ATM_ATM_ST	Q5UIP0	RIF1	Q13315	ATM	S1554	A1559V	1559	Missense	distal	5	no	9.723	9.888	EPSD	COSMIC	9.540	Up-regulation
Atypical_PIKK_ATM_ATM_ST	Q5UIP0	RIF1	Q13315	ATM	S1616	E1620K	1620	Missense	distal	4	no	9.500	9.878	EPSD	COSMIC	9.540	Gain
Atypical_PIKK_ATM_ATM_ST	Q5UIP0	RIF1	Q13315	ATM	S1616	I1614T	1614	Missense	proximal	-2	no	9.500	10.102	EPSD	COSMIC	9.540	Gain
Atypical_PIKK_ATM_ATM_ST	Q5UIP0	RIF1	Q13315	ATM	S1616	D1611H	1611	Missense	distal	-5	no	9.500	9.759	EPSD	COSMIC	9.540	Gain
Atypical_PIKK_ATM_ATM_ST	Q5UIP0	RIF1	Q13315	ATM	S1707	G1701W	1701	Missense	distal	-6	no	9.647	9.500	EPSD	COSMIC	9.540	Loss
Atypical_PIKK_ATM_ATM_ST	Q5UIP0	RIF1	Q13315	ATM	S1760	A1765P	1765	Missense	distal	5	no	11.194	11.328	EPSD	COSMIC	9.540	Up-regulation
Atypical_PIKK_ATM_ATM_ST	Q5UIP0	RIF1	Q13315	ATM	S1772	A1765P	1765	Missense	distal	-7	no	9.763	9.623	EPSD	COSMIC	9.540	Down-regulation
Atypical_PIKK_ATM_ATM_ST	Q5UIP0	RIF1	Q13315	ATM	S1772	S1772G	1772	Missense	central	0	yes	9.763	0.000	EPSD	COSMIC	9.540	Loss
Atypical_PIKK_ATM_ATM_ST	Q5UIP0	RIF1	Q13315	ATM	S1774	S1772G	1772	Missense	proximal	-2	no	9.863	9.420	EPSD	COSMIC	9.540	Loss
Atypical_PIKK_ATM_ATM_ST	Q5UIP0	RIF1	Q13315	ATM	S1777	E1784K	1784	Missense	distal	7	no	14.969	14.996	EPSD	COSMIC;GDSC;CCLE	9.540	Up-regulation
Atypical_PIKK_ATM_ATM_ST	Q5UIP0	RIF1	Q13315	ATM	S1777	S1772G	1772	Missense	distal	-5	no	14.969	15.024	EPSD	COSMIC	9.540	Up-regulation
Atypical_PIKK_ATM_ATM_ST	Q5UIP0	RIF1	Q13315	ATM	S1826	P1828S	1828	Missense	proximal	2	no	9.782	10.237	EPSD	COSMIC	9.540	Up-regulation
Atypical_PIKK_ATM_ATM_ST	Q5UIP0	RIF1	Q13315	ATM	S1844	I1838M	1838	Missense	distal	-6	no	10.079	10.234	EPSD	COSMIC	9.540	Up-regulation
Atypical_PIKK_ATM_ATM_ST	Q5UIP0	RIF1	Q13315	ATM	S1844	M1841I	1841	Missense	distal	-3	no	10.079	10.393	EPSD	COSMIC	9.540	Up-regulation
Atypical_PIKK_ATM_ATM_ST	Q5UIP0	RIF1	Q13315	ATM	S1848	M1841I	1841	Missense	distal	-7	no	10.557	10.368	EPSD	COSMIC	9.540	Down-regulation
Atypical_PIKK_ATM_ATM_ST	Q5UIP0	RIF1	Q13315	ATM	S1851	N1856D	1856	Missense	distal	5	no	14.608	14.719	PhosphoSitePlus	COSMIC;CCLE	9.540	Up-regulation
Atypical_PIKK_ATM_ATM_ST	Q5UIP0	RIF1	Q13315	ATM	S1854	N1856D	1856	Missense	proximal	2	no	11.330	12.352	EPSD	COSMIC;CCLE	9.540	Up-regulation
Atypical_PIKK_ATM_ATM_ST	Q5UIP0	RIF1	Q13315	ATM	S1873	E1878K	1878	Missense	distal	5	no	13.126	13.300	EPSD	COSMIC;GDSC;CCLE	9.540	Up-regulation
Atypical_PIKK_ATM_ATM_ST	Q5UIP0	RIF1	Q13315	ATM	S1873	V1872I	1872	Missense	proximal	-1	no	13.126	13.328	EPSD	COSMIC	9.540	Up-regulation
Atypical_PIKK_ATM_ATM_ST	Q5UIP0	RIF1	Q13315	ATM	S2117	Q2118H	2118	Missense	proximal	1	no	13.286	-1.623	EPSD	COSMIC	9.540	Loss
Atypical_PIKK_ATM_ATM_ST	Q5UIP0	RIF1	Q13315	ATM	S2124	Q2118H	2118	Missense	distal	-6	no	14.155	14.013	EPSD	COSMIC	9.540	Down-regulation
Atypical_PIKK_ATM_ATM_ST	Q5UIP0	RIF1	Q13315	ATM	S2124	T2131K	2131	Missense	distal	7	no	14.155	14.161	EPSD	COSMIC	9.540	Up-regulation
Atypical_PIKK_ATM_ATM_ST	Q5UIP0	RIF1	Q13315	ATM	S2129	T2131K	2131	Missense	proximal	2	no	11.021	10.463	EPSD	COSMIC	9.540	Down-regulation
Atypical_PIKK_ATM_ATM_ST	Q5UIP0	RIF1	Q13315	ATM	S2161	S2163G	2163	Missense	proximal	2	no	10.642	9.783	EPSD	COSMIC	9.540	Down-regulation
Atypical_PIKK_ATM_ATM_ST	Q5UIP0	RIF1	Q13315	ATM	S2176	T2179M	2179	Missense	distal	3	no	9.979	10.155	EPSD	COSMIC	9.540	Up-regulation
Atypical_PIKK_ATM_ATM_ST	Q5UIP0	RIF1	Q13315	ATM	S2189	E2191K	2191	Missense	proximal	2	no	13.821	12.490	EPSD	COSMIC	9.540	Down-regulation
Atypical_PIKK_ATM_ATM_ST	Q5UIP0	RIF1	Q13315	ATM	S2189	D2192E	2192	Missense	distal	3	no	13.821	13.462	EPSD	COSMIC	9.540	Down-regulation
Atypical_PIKK_ATM_ATM_ST	Q5UIP0	RIF1	Q13315	ATM	S2196	E2191K	2191	Missense	distal	-5	no	10.128	10.210	EPSD	COSMIC	9.540	Up-regulation
Atypical_PIKK_ATM_ATM_ST	Q5UIP0	RIF1	Q13315	ATM	S2196	D2192E	2192	Missense	distal	-4	no	10.128	10.411	EPSD	COSMIC	9.540	Up-regulation
Atypical_PIKK_ATM_ATM_ST	Q5UIP0	RIF1	Q13315	ATM	S2243	H2250R	2250	Missense	distal	7	no	10.397	10.403	EPSD	COSMIC	9.540	Up-regulation
Atypical_PIKK_ATM_ATM_ST	Q5UIP0	RIF1	Q13315	ATM	T2246	H2250R	2250	Missense	distal	4	no	14.199	14.264	EPSD	COSMIC	9.540	Up-regulation
Atypical_PIKK_ATM_ATM_ST	Q5UIP0	RIF1	Q13315	ATM	S2393	E2396D	2396	Missense	distal	3	no	9.358	9.717	EPSD	COSMIC	9.540	Gain
Atypical_PIKK_ATM_ATM_ST	Q5UIP0	RIF1	Q13315	ATM	S2465	L2459V	2459	Missense	distal	-6	no	13.660	13.692	EPSD	COSMIC	9.540	Up-regulation
Atypical_PIKK_ATM_ATM_ST	Q5UIP0	RIF1	Q13315	ATM	S2465	R2462H	2462	Missense	distal	-3	no	13.660	13.015	EPSD	COSMIC	9.540	Down-regulation
Atypical_PIKK_ATM_ATM_ST	Q5UIP0	RIF1	Q13315	ATM	S2465	S2471T	2471	Missense	distal	6	no	13.660	13.651	EPSD	COSMIC	9.540	Down-regulation
Atypical_PIKK_ATM_ATM_ST	Q13541	EIF4EBP1	Q13315	ATM	S94	N100H	100	Missense	distal	6	no	15.970	15.947	PhosphoSitePlus	COSMIC	9.540	Down-regulation
Atypical_PIKK_ATM_ATM_ST	Q13541	EIF4EBP1	Q13315	ATM	S101	N100H	100	Missense	proximal	-1	no	12.020	11.870	EPSD	COSMIC	9.540	Down-regulation
Atypical_PIKK_ATM_ATM_ST	Q13541	EIF4EBP1	Q13315	ATM	S101	R106L	106	Missense	distal	5	no	12.020	12.019	EPSD	COSMIC	9.540	Down-regulation
Atypical_PIKK_ATM_ATM_ST	Q13541	EIF4EBP1	Q13315	ATM	S112	R106L	106	Missense	distal	-6	no	15.382	15.275	EPSD	COSMIC	9.540	Down-regulation
Atypical_PIKK_ATM_ATM_ST	O15164	TRIM24	Q13315	ATM	S41	A48D	48	Missense	distal	7	no	9.632	9.610	EPSD	COSMIC	9.540	Down-regulation
Atypical_PIKK_ATM_ATM_ST	O15164	TRIM24	Q13315	ATM	S209	E207K	207	Missense	proximal	-2	no	11.788	11.212	EPSD	COSMIC	9.540	Down-regulation
Atypical_PIKK_ATM_ATM_ST	O15164	TRIM24	Q13315	ATM	S209	V208A	208	Missense	proximal	-1	no	11.788	12.051	EPSD	COSMIC	9.540	Up-regulation
Atypical_PIKK_ATM_ATM_ST	O15164	TRIM24	Q13315	ATM	S217	Q218H	218	Missense	proximal	1	no	14.219	-0.690	EPSD	COSMIC	9.540	Loss
Atypical_PIKK_ATM_ATM_ST	O15164	TRIM24	Q13315	ATM	S217	R219Q	219	Missense	proximal	2	no	14.219	14.915	EPSD	COSMIC	9.540	Up-regulation
Atypical_PIKK_ATM_ATM_ST	O15164	TRIM24	Q13315	ATM	S445	S445L	445	Missense	central	0	yes	14.715	0.000	EPSD	COSMIC;CCLE	9.540	Loss
Atypical_PIKK_ATM_ATM_ST	O15164	TRIM24	Q13315	ATM	S445	G450D	450	Missense	distal	5	no	14.715	14.623	EPSD	COSMIC	9.540	Down-regulation
Atypical_PIKK_ATM_ATM_ST	O15164	TRIM24	Q13315	ATM	S445	G450V	450	Missense	distal	5	no	14.715	14.749	EPSD	COSMIC	9.540	Up-regulation
Atypical_PIKK_ATM_ATM_ST	O15164	TRIM24	Q13315	ATM	S590	S583I	583	Missense	distal	-7	no	11.025	10.360	EPSD	COSMIC	9.540	Down-regulation
Atypical_PIKK_ATM_ATM_ST	O15164	TRIM24	Q13315	ATM	S685	V679L	679	Missense	distal	-6	no	9.650	9.619	EPSD	COSMIC	9.540	Down-regulation
Atypical_PIKK_ATM_ATM_ST	O15164	TRIM24	Q13315	ATM	S685	I683M	683	Missense	proximal	-2	no	9.650	9.901	EPSD	COSMIC	9.540	Up-regulation
Atypical_PIKK_ATM_ATM_ST	O15164	TRIM24	Q13315	ATM	S701	A704T	704	Missense	distal	3	no	10.813	10.838	EPSD	COSMIC	9.540	Up-regulation
Atypical_PIKK_ATM_ATM_ST	O15164	TRIM24	Q13315	ATM	S701	G695R	695	Missense	distal	-6	no	10.813	10.834	EPSD	COSMIC	9.540	Up-regulation
Atypical_PIKK_ATM_ATM_ST	O15164	TRIM24	Q13315	ATM	S701	D707H	707	Missense	distal	6	no	10.813	10.802	EPSD	COSMIC	9.540	Down-regulation
Atypical_PIKK_ATM_ATM_ST	O15164	TRIM24	Q13315	ATM	S701	S696N	696	Missense	distal	-5	no	10.813	10.785	EPSD	COSMIC	9.540	Down-regulation
Atypical_PIKK_ATM_ATM_ST	O15164	TRIM24	Q13315	ATM	S762	S767G	767	Missense	distal	5	no	10.008	10.187	EPSD	COSMIC;GDSC;CCLE	9.540	Up-regulation
Atypical_PIKK_ATM_ATM_ST	O15164	TRIM24	Q13315	ATM	S762	P756S	756	Missense	distal	-6	no	10.008	10.067	EPSD	COSMIC	9.540	Up-regulation
Atypical_PIKK_ATM_ATM_ST	O15164	TRIM24	Q13315	ATM	S762	L763Q	763	Missense	proximal	1	no	10.008	16.365	EPSD	COSMIC	9.540	Up-regulation
Atypical_PIKK_ATM_ATM_ST	O15164	TRIM24	Q13315	ATM	S768	S767G	767	Missense	proximal	-1	no	14.556	14.365	PhosphoSitePlus	COSMIC;GDSC;CCLE	9.540	Down-regulation
Atypical_PIKK_ATM_ATM_ST	O15164	TRIM24	Q13315	ATM	S768	E774Q	774	Missense	distal	6	no	14.556	14.510	PhosphoSitePlus	COSMIC	9.540	Down-regulation
Atypical_PIKK_ATM_ATM_ST	O15164	TRIM24	Q13315	ATM	S768	T772A	772	Missense	distal	4	no	14.556	14.121	PhosphoSitePlus	COSMIC	9.540	Down-regulation
Atypical_PIKK_ATM_ATM_ST	O15164	TRIM24	Q13315	ATM	S768	L763Q	763	Missense	distal	-5	no	14.556	14.400	PhosphoSitePlus	COSMIC	9.540	Down-regulation
Atypical_PIKK_ATM_ATM_ST	O15164	TRIM24	Q13315	ATM	S773	E774Q	774	Missense	proximal	1	no	9.405	15.301	EPSD	COSMIC	9.540	Gain
Atypical_PIKK_ATM_ATM_ST	O15164	TRIM24	Q13315	ATM	S808	S808F	808	Missense	central	0	yes	13.483	0.000	EPSD	COSMIC	9.540	Loss
Atypical_PIKK_ATM_ATM_ST	O15164	TRIM24	Q13315	ATM	S808	P812S	812	Missense	distal	4	no	13.483	13.360	EPSD	COSMIC	9.540	Down-regulation
Atypical_PIKK_ATM_ATM_ST	O15164	TRIM24	Q13315	ATM	S811	S808F	808	Missense	distal	-3	no	10.048	11.120	EPSD	COSMIC	9.540	Up-regulation
Atypical_PIKK_ATM_ATM_ST	O15164	TRIM24	Q13315	ATM	S811	P812S	812	Missense	proximal	1	no	10.048	3.073	EPSD	COSMIC	9.540	Loss
Atypical_PIKK_ATM_ATM_ST	O15164	TRIM24	Q13315	ATM	S1019	D1021Y	1021	Missense	proximal	2	no	10.117	8.876	EPSD	COSMIC	9.540	Loss
Atypical_PIKK_ATM_ATM_ST	O15164	TRIM24	Q13315	ATM	S1019	K1023Q	1023	Missense	distal	4	no	10.117	10.071	EPSD	COSMIC	9.540	Down-regulation
Atypical_PIKK_ATM_ATM_ST	O15164	TRIM24	Q13315	ATM	S1025	D1030N	1030	Missense	distal	5	no	11.093	10.982	EPSD	COSMIC	9.540	Down-regulation
Atypical_PIKK_ATM_ATM_ST	O15164	TRIM24	Q13315	ATM	S1025	D1021Y	1021	Missense	distal	-4	no	11.093	9.997	EPSD	COSMIC	9.540	Down-regulation
Atypical_PIKK_ATM_ATM_ST	O15164	TRIM24	Q13315	ATM	S1025	K1023Q	1023	Missense	proximal	-2	no	11.093	11.364	EPSD	COSMIC	9.540	Up-regulation
Atypical_PIKK_ATM_ATM_ST	O43504	LAMTOR5	Q13315	ATM	S26	C23S	23	Missense	distal	-3	no	14.620	14.452	PhosphoSitePlus	COSMIC	9.540	Down-regulation
Atypical_PIKK_ATM_ATM_ST	O43504	LAMTOR5	Q13315	ATM	S26	D25N	25	Missense	proximal	-1	no	14.620	14.619	PhosphoSitePlus	COSMIC	9.540	Down-regulation
Atypical_PIKK_ATM_ATM_ST	Q92630	DYRK2	Q13315	ATM	T106	L104F	104	Missense	proximal	-2	no	14.045	13.534	PhosphoSitePlus;EPSD	COSMIC	9.540	Down-regulation
Atypical_PIKK_ATM_ATM_ST	Q92630	DYRK2	Q13315	ATM	T106	V103E	103	Missense	distal	-3	no	14.045	13.467	PhosphoSitePlus;EPSD	COSMIC	9.540	Down-regulation
Atypical_PIKK_ATM_ATM_ST	Q92630	DYRK2	Q13315	ATM	T106	L111F	111	Missense	distal	5	no	14.045	14.187	PhosphoSitePlus;EPSD	COSMIC	9.540	Up-regulation
Atypical_PIKK_ATM_ATM_ST	P51532	SMARCA4	Q13315	ATM	S117	S122L	122	Missense	distal	5	no	13.976	14.141	EPSD	COSMIC	9.540	Up-regulation
Atypical_PIKK_ATM_ATM_ST	P51532	SMARCA4	Q13315	ATM	S117	S117F	117	Missense	central	0	yes	13.976	0.000	EPSD	COSMIC	9.540	Loss
Atypical_PIKK_ATM_ATM_ST	P51532	SMARCA4	Q13315	ATM	S323	V325M	325	Missense	proximal	2	no	10.178	10.013	EPSD	COSMIC	9.540	Down-regulation
Atypical_PIKK_ATM_ATM_ST	P51532	SMARCA4	Q13315	ATM	S323	A322T	322	Missense	proximal	-1	no	10.178	10.349	EPSD	COSMIC;GDSC;CCLE	9.540	Up-regulation
Atypical_PIKK_ATM_ATM_ST	P51532	SMARCA4	Q13315	ATM	S323	P320L	320	Missense	distal	-3	no	10.178	10.191	EPSD	COSMIC	9.540	Up-regulation
Atypical_PIKK_ATM_ATM_ST	P51532	SMARCA4	Q13315	ATM	S323	P324L	324	Missense	proximal	1	no	10.178	8.623	EPSD	COSMIC	9.540	Loss
Atypical_PIKK_ATM_ATM_ST	P51532	SMARCA4	Q13315	ATM	S323	P328L	328	Missense	distal	5	no	10.178	10.161	EPSD	COSMIC	9.540	Down-regulation
Atypical_PIKK_ATM_ATM_ST	P51532	SMARCA4	Q13315	ATM	S323	P316S	316	Missense	distal	-7	no	10.178	10.414	EPSD	COSMIC	9.540	Up-regulation
Atypical_PIKK_ATM_ATM_ST	P51532	SMARCA4	Q13315	ATM	S323	V318I	318	Missense	distal	-5	no	10.178	10.179	EPSD	COSMIC	9.540	Up-regulation
Atypical_PIKK_ATM_ATM_ST	P51532	SMARCA4	Q13315	ATM	S323	A317V	317	Missense	distal	-6	no	10.178	9.942	EPSD	COSMIC	9.540	Down-regulation
Atypical_PIKK_ATM_ATM_ST	P51532	SMARCA4	Q13315	ATM	T330	G334E	334	Missense	distal	4	no	12.328	11.901	EPSD	COSMIC	9.540	Down-regulation
Atypical_PIKK_ATM_ATM_ST	P51532	SMARCA4	Q13315	ATM	T330	V325M	325	Missense	distal	-5	no	12.328	12.299	EPSD	COSMIC	9.540	Down-regulation
Atypical_PIKK_ATM_ATM_ST	P51532	SMARCA4	Q13315	ATM	T330	S332F	332	Missense	proximal	2	no	12.328	10.850	EPSD	COSMIC	9.540	Down-regulation
Atypical_PIKK_ATM_ATM_ST	P51532	SMARCA4	Q13315	ATM	T330	P333L	333	Missense	distal	3	no	12.328	12.458	EPSD	COSMIC	9.540	Up-regulation
Atypical_PIKK_ATM_ATM_ST	P51532	SMARCA4	Q13315	ATM	T330	P324L	324	Missense	distal	-6	no	12.328	12.099	EPSD	COSMIC	9.540	Down-regulation
Atypical_PIKK_ATM_ATM_ST	P51532	SMARCA4	Q13315	ATM	T330	P328L	328	Missense	proximal	-2	no	12.328	12.175	EPSD	COSMIC	9.540	Down-regulation
Atypical_PIKK_ATM_ATM_ST	P51532	SMARCA4	Q13315	ATM	S610	T609S	609	Missense	proximal	-1	no	13.887	13.877	EPSD	COSMIC	9.540	Down-regulation
Atypical_PIKK_ATM_ATM_ST	P51532	SMARCA4	Q13315	ATM	S610	P616L	616	Missense	distal	6	no	13.887	13.841	EPSD	COSMIC	9.540	Down-regulation
Atypical_PIKK_ATM_ATM_ST	P51532	SMARCA4	Q13315	ATM	S657	R654K	654	Missense	distal	-3	no	10.774	9.941	EPSD	COSMIC	9.540	Down-regulation
Atypical_PIKK_ATM_ATM_ST	P51532	SMARCA4	Q13315	ATM	S662	E667K	667	Missense	distal	5	no	9.942	10.117	EPSD	COSMIC	9.540	Up-regulation
Atypical_PIKK_ATM_ATM_ST	P51532	SMARCA4	Q13315	ATM	S662	E668K	668	Missense	distal	6	no	9.942	9.897	EPSD	COSMIC	9.540	Down-regulation
Atypical_PIKK_ATM_ATM_ST	P51532	SMARCA4	Q13315	ATM	S721	V720M	720	Missense	proximal	-1	no	15.380	15.512	PhosphoSitePlus	COSMIC	9.540	Up-regulation
Atypical_PIKK_ATM_ATM_ST	P51532	SMARCA4	Q13315	ATM	S721	G719D	719	Missense	proximal	-2	no	15.380	15.525	PhosphoSitePlus	COSMIC	9.540	Up-regulation
Atypical_PIKK_ATM_ATM_ST	P51532	SMARCA4	Q13315	ATM	S721	L724F	724	Missense	distal	3	no	15.380	15.680	PhosphoSitePlus	COSMIC	9.540	Up-regulation
Atypical_PIKK_ATM_ATM_ST	P51532	SMARCA4	Q13315	ATM	S833	G836E	836	Missense	distal	3	no	10.726	10.419	EPSD	COSMIC	9.540	Down-regulation
Atypical_PIKK_ATM_ATM_ST	P51532	SMARCA4	Q13315	ATM	S833	K835N	835	Missense	proximal	2	no	10.726	10.904	EPSD	COSMIC	9.540	Up-regulation
Atypical_PIKK_ATM_ATM_ST	P51532	SMARCA4	Q13315	ATM	S833	A826V	826	Missense	distal	-7	no	10.726	10.342	EPSD	COSMIC	9.540	Down-regulation
Atypical_PIKK_ATM_ATM_ST	P51532	SMARCA4	Q13315	ATM	S833	S828F	828	Missense	distal	-5	no	10.726	11.049	EPSD	COSMIC	9.540	Up-regulation
Atypical_PIKK_ATM_ATM_ST	P51532	SMARCA4	Q13315	ATM	S833	P838S	838	Missense	distal	5	no	10.726	10.544	EPSD	COSMIC	9.540	Down-regulation
Atypical_PIKK_ATM_ATM_ST	P51532	SMARCA4	Q13315	ATM	S833	V829M	829	Missense	distal	-4	no	10.726	10.707	EPSD	COSMIC	9.540	Down-regulation
Atypical_PIKK_ATM_ATM_ST	P51532	SMARCA4	Q13315	ATM	S833	A826T	826	Missense	distal	-7	no	10.726	10.741	EPSD	COSMIC	9.540	Up-regulation
Atypical_PIKK_ATM_ATM_ST	P51532	SMARCA4	Q13315	ATM	S833	V830G	830	Missense	distal	-3	no	10.726	10.586	EPSD	COSMIC	9.540	Down-regulation
Atypical_PIKK_ATM_ATM_ST	P51532	SMARCA4	Q13315	ATM	S837	R842W	842	Missense	distal	5	no	12.345	12.369	EPSD	COSMIC	9.540	Up-regulation
Atypical_PIKK_ATM_ATM_ST	P51532	SMARCA4	Q13315	ATM	S837	G836E	836	Missense	proximal	-1	no	12.345	12.747	EPSD	COSMIC	9.540	Up-regulation
Atypical_PIKK_ATM_ATM_ST	P51532	SMARCA4	Q13315	ATM	S837	K835N	835	Missense	proximal	-2	no	12.345	12.561	EPSD	COSMIC	9.540	Up-regulation
Atypical_PIKK_ATM_ATM_ST	P51532	SMARCA4	Q13315	ATM	S837	P838S	838	Missense	proximal	1	no	12.345	5.370	EPSD	COSMIC	9.540	Loss
Atypical_PIKK_ATM_ATM_ST	P51532	SMARCA4	Q13315	ATM	S837	V830G	830	Missense	distal	-7	no	12.345	12.313	EPSD	COSMIC	9.540	Down-regulation
Atypical_PIKK_ATM_ATM_ST	P51532	SMARCA4	Q13315	ATM	T859	F853L	853	Missense	distal	-6	no	10.761	11.004	EPSD	COSMIC	9.540	Up-regulation
Atypical_PIKK_ATM_ATM_ST	P51532	SMARCA4	Q13315	ATM	T859	Y860H	860	Missense	proximal	1	no	10.761	1.568	EPSD	COSMIC	9.540	Loss
Atypical_PIKK_ATM_ATM_ST	P51532	SMARCA4	Q13315	ATM	T859	V855I	855	Missense	distal	-4	no	10.761	11.039	EPSD	COSMIC	9.540	Up-regulation
Atypical_PIKK_ATM_ATM_ST	P51532	SMARCA4	Q13315	ATM	T859	I864M	864	Missense	distal	5	no	10.761	10.737	EPSD	COSMIC	9.540	Down-regulation
Atypical_PIKK_ATM_ATM_ST	P51532	SMARCA4	Q13315	ATM	S1380	S1380L	1380	Missense	central	0	yes	9.956	0.000	EPSD	COSMIC	9.540	Loss
Atypical_PIKK_ATM_ATM_ST	P51532	SMARCA4	Q13315	ATM	S1380	K1375N	1375	Missense	distal	-5	no	9.956	10.012	EPSD	COSMIC	9.540	Up-regulation
Atypical_PIKK_ATM_ATM_ST	P51532	SMARCA4	Q13315	ATM	S1380	Q1387K	1387	Missense	distal	7	no	9.956	9.969	EPSD	COSMIC	9.540	Up-regulation
Atypical_PIKK_ATM_ATM_ST	P51532	SMARCA4	Q13315	ATM	S1380	K1386M	1386	Missense	distal	6	no	9.956	9.948	EPSD	COSMIC	9.540	Down-regulation
Atypical_PIKK_ATM_ATM_ST	P51532	SMARCA4	Q13315	ATM	S1380	R1374H	1374	Missense	distal	-6	no	9.956	9.957	EPSD	COSMIC	9.540	Up-regulation
Atypical_PIKK_ATM_ATM_ST	P51532	SMARCA4	Q13315	ATM	S1380	V1377L	1377	Missense	distal	-3	no	9.956	9.747	EPSD	COSMIC	9.540	Down-regulation
Atypical_PIKK_ATM_ATM_ST	P51532	SMARCA4	Q13315	ATM	S1380	T1384M	1384	Missense	distal	4	no	9.956	10.129	EPSD	COSMIC	9.540	Up-regulation
Atypical_PIKK_ATM_ATM_ST	P51532	SMARCA4	Q13315	ATM	S1382	K1386M	1386	Missense	distal	4	no	9.359	9.540	EPSD	COSMIC	9.540	Gain
Atypical_PIKK_ATM_ATM_ST	P51532	SMARCA4	Q13315	ATM	S1410	R1411Q	1411	Missense	proximal	1	no	7.706	14.357	EPSD	COSMIC	9.540	Gain
Atypical_PIKK_ATM_ATM_ST	P51532	SMARCA4	Q13315	ATM	S1452	P1456S	1456	Missense	distal	4	no	9.638	9.515	EPSD	COSMIC	9.540	Loss
Atypical_PIKK_ATM_ATM_ST	P51532	SMARCA4	Q13315	ATM	S1452	R1445H	1445	Missense	distal	-7	no	9.638	9.723	EPSD	COSMIC	9.540	Up-regulation
Atypical_PIKK_ATM_ATM_ST	P51532	SMARCA4	Q13315	ATM	S1452	E1449K	1449	Missense	distal	-3	no	9.638	9.705	EPSD	COSMIC	9.540	Up-regulation
Atypical_PIKK_ATM_ATM_ST	P51532	SMARCA4	Q13315	ATM	S1452	R1445Q	1445	Missense	distal	-7	no	9.638	9.837	EPSD	COSMIC	9.540	Up-regulation
Atypical_PIKK_ATM_ATM_ST	P51532	SMARCA4	Q13315	ATM	S1452	P1456L	1456	Missense	distal	4	no	9.638	9.857	EPSD	COSMIC;CCLE	9.540	Up-regulation
Atypical_PIKK_ATM_ATM_ST	P51532	SMARCA4	Q13315	ATM	S1452	P1453H	1453	Missense	proximal	1	no	9.638	-0.469	EPSD	COSMIC	9.540	Loss
Atypical_PIKK_ATM_ATM_ST	P51532	SMARCA4	Q13315	ATM	S1452	N1457S	1457	Missense	distal	5	no	9.638	9.663	EPSD	COSMIC	9.540	Up-regulation
Atypical_PIKK_ATM_ATM_ST	P51532	SMARCA4	Q13315	ATM	S1452	L1458I	1458	Missense	distal	6	no	9.638	9.654	EPSD	COSMIC	9.540	Up-regulation
Atypical_PIKK_ATM_ATM_ST	P51532	SMARCA4	Q13315	ATM	S1452	P1447R	1447	Missense	distal	-5	no	9.638	9.710	EPSD	COSMIC	9.540	Up-regulation
Atypical_PIKK_ATM_ATM_ST	P51532	SMARCA4	Q13315	ATM	S1452	P1455L	1455	Missense	distal	3	no	9.638	9.768	EPSD	COSMIC	9.540	Up-regulation
Atypical_PIKK_ATM_ATM_ST	P51532	SMARCA4	Q13315	ATM	S1452	P1455Q	1455	Missense	distal	3	no	9.638	9.569	EPSD	COSMIC;CCLE	9.540	Down-regulation
Atypical_PIKK_ATM_ATM_ST	P51532	SMARCA4	Q13315	ATM	S1452	L1451F	1451	Missense	proximal	-1	no	9.638	9.347	EPSD	COSMIC	9.540	Loss
Atypical_PIKK_ATM_ATM_ST	P51532	SMARCA4	Q13315	ATM	S1452	R1445C	1445	Missense	distal	-7	no	9.638	9.363	EPSD	COSMIC	9.540	Loss
Atypical_PIKK_ATM_ATM_ST	P51532	SMARCA4	Q13315	ATM	S1452	P1455H	1455	Missense	distal	3	no	9.638	9.709	EPSD	COSMIC	9.540	Up-regulation
Atypical_PIKK_ATM_ATM_ST	P51532	SMARCA4	Q13315	ATM	S1452	P1455T	1455	Missense	distal	3	no	9.638	9.567	EPSD	COSMIC	9.540	Down-regulation
Atypical_PIKK_ATM_ATM_ST	P51532	SMARCA4	Q13315	ATM	S1452	P1446R	1446	Missense	distal	-6	no	9.638	9.517	EPSD	COSMIC	9.540	Loss
Atypical_PIKK_ATM_ATM_ST	P51532	SMARCA4	Q13315	ATM	S1452	R1445L	1445	Missense	distal	-7	no	9.638	9.449	EPSD	COSMIC	9.540	Loss
Atypical_PIKK_ATM_ATM_ST	P51532	SMARCA4	Q13315	ATM	S1490	R1491Q	1491	Missense	proximal	1	no	8.163	14.814	EPSD	COSMIC	9.540	Gain
Atypical_PIKK_ATM_ATM_ST	P51532	SMARCA4	Q13315	ATM	S1575	E1576Q	1576	Missense	proximal	1	no	8.792	14.689	EPSD	COSMIC	9.540	Gain
Atypical_PIKK_ATM_ATM_ST	P51532	SMARCA4	Q13315	ATM	S1586	S1590F	1590	Missense	distal	4	no	11.512	12.340	EPSD	COSMIC	9.540	Up-regulation
Atypical_PIKK_ATM_ATM_ST	P51532	SMARCA4	Q13315	ATM	S1586	V1593M	1593	Missense	distal	7	no	11.512	11.497	EPSD	COSMIC	9.540	Down-regulation
Atypical_PIKK_ATM_ATM_ST	P51532	SMARCA4	Q13315	ATM	S1586	S1586F	1586	Missense	central	0	yes	11.512	0.000	EPSD	COSMIC	9.540	Loss
Atypical_PIKK_ATM_ATM_ST	P51532	SMARCA4	Q13315	ATM	S1586	S1592F	1592	Missense	distal	6	no	11.512	11.436	EPSD	COSMIC	9.540	Down-regulation
Atypical_PIKK_ATM_ATM_ST	P51532	SMARCA4	Q13315	ATM	S1586	V1593I	1593	Missense	distal	7	no	11.512	11.495	EPSD	COSMIC	9.540	Down-regulation
Atypical_PIKK_ATM_ATM_ST	P51532	SMARCA4	Q13315	ATM	S1586	E1584K	1584	Missense	proximal	-2	no	11.512	10.937	EPSD	COSMIC	9.540	Down-regulation
Atypical_PIKK_ATM_ATM_ST	P51532	SMARCA4	Q13315	ATM	S1586	E1579Q	1579	Missense	distal	-7	no	11.512	10.958	EPSD	COSMIC	9.540	Down-regulation
Atypical_PIKK_ATM_ATM_ST	P51532	SMARCA4	Q13315	ATM	S1586	S1586G	1586	Missense	central	0	yes	11.512	0.000	EPSD	COSMIC	9.540	Loss
Atypical_PIKK_ATM_ATM_ST	P51532	SMARCA4	Q13315	ATM	S1586	S1586N	1586	Missense	central	0	yes	11.512	0.000	EPSD	COSMIC	9.540	Loss
Atypical_PIKK_ATM_ATM_ST	P51532	SMARCA4	Q13315	ATM	S1586	G1581S	1581	Missense	distal	-5	no	11.512	11.457	EPSD	COSMIC	9.540	Down-regulation
Atypical_PIKK_ATM_ATM_ST	P51532	SMARCA4	Q13315	ATM	S1588	S1592F	1592	Missense	distal	4	no	9.494	10.322	EPSD	COSMIC	9.540	Gain
Atypical_PIKK_ATM_ATM_ST	P51532	SMARCA4	Q13315	ATM	S1588	G1581S	1581	Missense	distal	-7	no	9.494	10.006	EPSD	COSMIC	9.540	Gain
Atypical_PIKK_ATM_ATM_ST	P51532	SMARCA4	Q13315	ATM	S1590	S1590F	1590	Missense	central	0	yes	11.268	0.000	EPSD	COSMIC	9.540	Loss
Atypical_PIKK_ATM_ATM_ST	P51532	SMARCA4	Q13315	ATM	S1590	V1593M	1593	Missense	distal	3	no	11.268	11.180	EPSD	COSMIC	9.540	Down-regulation
Atypical_PIKK_ATM_ATM_ST	P51532	SMARCA4	Q13315	ATM	S1590	S1586F	1586	Missense	distal	-4	no	11.268	9.869	EPSD	COSMIC	9.540	Down-regulation
Atypical_PIKK_ATM_ATM_ST	P51532	SMARCA4	Q13315	ATM	S1590	S1592F	1592	Missense	proximal	2	no	11.268	9.789	EPSD	COSMIC	9.540	Down-regulation
Atypical_PIKK_ATM_ATM_ST	P51532	SMARCA4	Q13315	ATM	S1590	V1593I	1593	Missense	distal	3	no	11.268	11.425	EPSD	COSMIC	9.540	Up-regulation
Atypical_PIKK_ATM_ATM_ST	P51532	SMARCA4	Q13315	ATM	S1590	E1584K	1584	Missense	distal	-6	no	11.268	10.967	EPSD	COSMIC	9.540	Down-regulation
Atypical_PIKK_ATM_ATM_ST	P51532	SMARCA4	Q13315	ATM	S1590	V1595I	1595	Missense	distal	5	no	11.268	11.265	EPSD	COSMIC	9.540	Down-regulation
Atypical_PIKK_ATM_ATM_ST	P51532	SMARCA4	Q13315	ATM	S1590	S1586G	1586	Missense	distal	-4	no	11.268	10.480	EPSD	COSMIC	9.540	Down-regulation
Atypical_PIKK_ATM_ATM_ST	P51532	SMARCA4	Q13315	ATM	S1590	V1595M	1595	Missense	distal	5	no	11.268	11.240	EPSD	COSMIC	9.540	Down-regulation
Atypical_PIKK_ATM_ATM_ST	P51532	SMARCA4	Q13315	ATM	S1590	S1586N	1586	Missense	distal	-4	no	11.268	10.339	EPSD	COSMIC	9.540	Down-regulation
Atypical_PIKK_ATM_ATM_ST	P51532	SMARCA4	Q13315	ATM	S1617	R1618Q	1618	Missense	proximal	1	no	5.572	12.223	EPSD	COSMIC	9.540	Gain
Atypical_PIKK_ATM_ATM_ST	P51532	SMARCA4	Q13315	ATM	S1640	D1638H	1638	Missense	proximal	-2	no	10.738	10.609	EPSD	COSMIC	9.540	Down-regulation
Atypical_PIKK_ATM_ATM_ST	P51532	SMARCA4	Q13315	ATM	S1640	E1646K	1646	Missense	distal	6	no	10.738	10.692	EPSD	COSMIC	9.540	Down-regulation
Atypical_PIKK_ATM_ATM_ST	P51532	SMARCA4	Q13315	ATM	S1640	E1633A	1633	Missense	distal	-7	no	10.738	10.285	EPSD	COSMIC	9.540	Down-regulation
Atypical_PIKK_ATM_ATM_ST	P51532	SMARCA4	Q13315	ATM	S1640	R1639C	1639	Missense	proximal	-1	no	10.738	10.913	EPSD	COSMIC	9.540	Up-regulation
Atypical_PIKK_ATM_ATM_ST	P51532	SMARCA4	Q13315	ATM	S1640	E1645K	1645	Missense	distal	5	no	10.738	10.912	EPSD	COSMIC	9.540	Up-regulation
Atypical_PIKK_ATM_ATM_ST	P51532	SMARCA4	Q13315	ATM	S1642	D1638H	1638	Missense	distal	-4	no	9.642	8.966	EPSD	COSMIC	9.540	Loss
Atypical_PIKK_ATM_ATM_ST	P51532	SMARCA4	Q13315	ATM	S1642	E1646K	1646	Missense	distal	4	no	9.642	10.019	EPSD	COSMIC	9.540	Up-regulation
Atypical_PIKK_ATM_ATM_ST	P51532	SMARCA4	Q13315	ATM	S1642	R1639C	1639	Missense	distal	-3	no	9.642	9.069	EPSD	COSMIC	9.540	Loss
Atypical_PIKK_ATM_ATM_ST	P51532	SMARCA4	Q13315	ATM	S1642	E1645K	1645	Missense	distal	3	no	9.642	9.931	EPSD	COSMIC	9.540	Up-regulation
Atypical_PIKK_ATM_ATM_ST	P51532	SMARCA4	Q13315	ATM	S1644	D1638H	1638	Missense	distal	-6	no	13.851	13.699	EPSD	COSMIC	9.540	Down-regulation
Atypical_PIKK_ATM_ATM_ST	P51532	SMARCA4	Q13315	ATM	S1644	E1646K	1646	Missense	proximal	2	no	13.851	12.520	EPSD	COSMIC	9.540	Down-regulation
Atypical_PIKK_ATM_ATM_ST	P51532	SMARCA4	Q13315	ATM	S1644	R1639C	1639	Missense	distal	-5	no	13.851	13.868	EPSD	COSMIC	9.540	Up-regulation
Atypical_PIKK_ATM_ATM_ST	P51532	SMARCA4	Q13315	ATM	S1644	E1645K	1645	Missense	proximal	1	no	13.851	12.899	EPSD	COSMIC	9.540	Down-regulation
Atypical_PIKK_ATM_ATM_ST	Q03111	MLLT1	Q13315	ATM	S209	R204W	204	Missense	distal	-5	no	9.721	9.886	EPSD	COSMIC	9.540	Up-regulation
Atypical_PIKK_ATM_ATM_ST	Q03111	MLLT1	Q13315	ATM	S361	E364K	364	Missense	distal	3	no	9.882	10.171	EPSD	COSMIC	9.540	Up-regulation
Atypical_PIKK_ATM_ATM_ST	Q03111	MLLT1	Q13315	ATM	S387	E392Q	392	Missense	distal	5	no	11.725	11.949	EPSD	COSMIC	9.540	Up-regulation
Atypical_PIKK_ATM_ATM_ST	Q03111	MLLT1	Q13315	ATM	S394	E392Q	392	Missense	proximal	-2	no	17.632	17.327	EPSD;PhosphoSitePlus	COSMIC	9.540	Down-regulation
Atypical_PIKK_ATM_ATM_ST	Q03111	MLLT1	Q13315	ATM	S398	E392Q	392	Missense	distal	-6	no	15.392	15.168	PhosphoSitePlus;EPSD	COSMIC	9.540	Down-regulation
Atypical_PIKK_ATM_ATM_ST	Q03111	MLLT1	Q13315	ATM	S411	D415N	415	Missense	distal	4	no	11.723	11.642	EPSD	COSMIC	9.540	Down-regulation
Atypical_PIKK_ATM_ATM_ST	Q03111	MLLT1	Q13315	ATM	S411	E416K	416	Missense	distal	5	no	11.723	11.898	EPSD	COSMIC	9.540	Up-regulation
Atypical_PIKK_ATM_ATM_ST	Q03111	MLLT1	Q13315	ATM	S414	D415N	415	Missense	proximal	1	no	10.442	6.612	EPSD	COSMIC	9.540	Loss
Atypical_PIKK_ATM_ATM_ST	Q03111	MLLT1	Q13315	ATM	S414	E416K	416	Missense	proximal	2	no	10.442	9.111	EPSD	COSMIC	9.540	Loss
Atypical_PIKK_ATM_ATM_ST	Q03111	MLLT1	Q13315	ATM	S421	G422C	422	Missense	proximal	1	no	10.097	4.360	EPSD	COSMIC	9.540	Loss
Atypical_PIKK_ATM_ATM_ST	Q03111	MLLT1	Q13315	ATM	S421	D415N	415	Missense	distal	-6	no	10.097	10.008	EPSD	COSMIC	9.540	Down-regulation
Atypical_PIKK_ATM_ATM_ST	Q03111	MLLT1	Q13315	ATM	S421	E416K	416	Missense	distal	-5	no	10.097	10.178	EPSD	COSMIC	9.540	Up-regulation
Atypical_PIKK_ATM_ATM_ST	Q03111	MLLT1	Q13315	ATM	S442	D449N	449	Missense	distal	7	no	11.548	11.554	EPSD	COSMIC	9.540	Up-regulation
Atypical_PIKK_ATM_ATM_ST	Q03111	MLLT1	Q13315	ATM	S451	L452Q	452	Missense	proximal	1	no	8.948	15.304	EPSD	COSMIC	9.540	Gain
Atypical_PIKK_ATM_ATM_ST	Q03111	MLLT1	Q13315	ATM	S454	L452Q	452	Missense	proximal	-2	no	10.404	10.669	EPSD	COSMIC	9.540	Up-regulation
Atypical_PIKK_ATM_ATM_ST	Q03111	MLLT1	Q13315	ATM	S454	D449N	449	Missense	distal	-5	no	10.404	10.587	EPSD	COSMIC	9.540	Up-regulation
Atypical_PIKK_ATM_ATM_ST	Q03111	MLLT1	Q13315	ATM	S475	R473Q	473	Missense	proximal	-2	no	12.248	12.567	EPSD	COSMIC	9.540	Up-regulation
Atypical_PIKK_ATM_ATM_ST	Q03111	MLLT1	Q13315	ATM	S475	K481R	481	Missense	distal	6	no	12.248	12.252	EPSD	COSMIC	9.540	Up-regulation
Atypical_PIKK_ATM_ATM_ST	Q8IZL8	PELP1	Q13315	ATM	S251	A248T	248	Missense	distal	-3	no	12.382	12.759	EPSD	COSMIC	9.540	Up-regulation
Atypical_PIKK_ATM_ATM_ST	Q8IZL8	PELP1	Q13315	ATM	S477	P478Q	478	Missense	proximal	1	no	6.416	11.217	EPSD	COSMIC	9.540	Gain
Atypical_PIKK_ATM_ATM_ST	Q8IZL8	PELP1	Q13315	ATM	S481	P478Q	478	Missense	distal	-3	no	9.663	9.431	EPSD	COSMIC	9.540	Loss
Atypical_PIKK_ATM_ATM_ST	Q8IZL8	PELP1	Q13315	ATM	T807	P808Q	808	Missense	proximal	1	no	6.417	11.219	EPSD	COSMIC	9.540	Gain
Atypical_PIKK_ATM_ATM_ST	Q8IZL8	PELP1	Q13315	ATM	S1033	S1033C	1033	Missense	central	0	yes	13.675	0.000	PhosphoSitePlus	COSMIC	9.540	Loss
Atypical_PIKK_ATM_ATM_ST	Q8IZL8	PELP1	Q13315	ATM	S1033	S1033F	1033	Missense	central	0	yes	13.675	0.000	PhosphoSitePlus	COSMIC	9.540	Loss
Atypical_PIKK_ATM_ATM_ST	Q8IZL8	PELP1	Q13315	ATM	S1033	P1028L	1028	Missense	distal	-5	no	13.675	13.694	PhosphoSitePlus	COSMIC	9.540	Up-regulation
Atypical_PIKK_ATM_ATM_ST	Q8IZL8	PELP1	Q13315	ATM	S1033	E1036K	1036	Missense	distal	3	no	13.675	13.964	PhosphoSitePlus	COSMIC	9.540	Up-regulation
Atypical_PIKK_ATM_ATM_ST	Q8IZL8	PELP1	Q13315	ATM	S1033	E1040V	1040	Missense	distal	7	no	13.675	13.727	PhosphoSitePlus	COSMIC	9.540	Up-regulation
Atypical_PIKK_ATM_ATM_ST	Q8IZL8	PELP1	Q13315	ATM	S1043	E1040V	1040	Missense	distal	-3	no	9.443	10.020	EPSD	COSMIC	9.540	Gain
Atypical_PIKK_ATM_ATM_ST	Q9HB75	PIDD1	Q13315	ATM	S299	P294L	294	Missense	distal	-5	no	11.416	11.435	EPSD	COSMIC	9.540	Up-regulation
Atypical_PIKK_ATM_ATM_ST	Q9HB75	PIDD1	Q13315	ATM	S299	G292W	292	Missense	distal	-7	no	11.416	11.340	EPSD	COSMIC	9.540	Down-regulation
Atypical_PIKK_ATM_ATM_ST	Q9HB75	PIDD1	Q13315	ATM	S299	P300A	300	Missense	proximal	1	no	11.416	9.344	EPSD	COSMIC	9.540	Loss
Atypical_PIKK_ATM_ATM_ST	Q9HB75	PIDD1	Q13315	ATM	T788	D781N	781	Missense	distal	-7	no	14.068	14.104	PhosphoSitePlus	COSMIC	9.540	Up-regulation
Atypical_PIKK_ATM_ATM_ST	Q9HB75	PIDD1	Q13315	ATM	T788	T784S	784	Missense	distal	-4	no	14.068	14.451	PhosphoSitePlus	COSMIC	9.540	Up-regulation
Atypical_PIKK_ATM_ATM_ST	Q9HB75	PIDD1	Q13315	ATM	T788	L793P	793	Missense	distal	5	no	14.068	14.085	PhosphoSitePlus	COSMIC	9.540	Up-regulation
Atypical_PIKK_ATM_ATM_ST	O14757	CHEK1	Q13315	ATM	S317	P321L	321	Missense	distal	4	no	16.627	16.846	EPSD	COSMIC	9.540	Up-regulation
Atypical_PIKK_ATM_ATM_ST	O14757	CHEK1	Q13315	ATM	S317	P321T	321	Missense	distal	4	no	16.627	16.592	EPSD	COSMIC	9.540	Down-regulation
Atypical_PIKK_ATM_ATM_ST	O14757	CHEK1	Q13315	ATM	S317	R322C	322	Missense	distal	5	no	16.627	16.688	EPSD	COSMIC	9.540	Up-regulation
Atypical_PIKK_ATM_ATM_ST	O14757	CHEK1	Q13315	ATM	S317	V312M	312	Missense	distal	-5	no	16.627	16.598	EPSD	COSMIC;CCLE	9.540	Down-regulation
Atypical_PIKK_ATM_ATM_ST	O14757	CHEK1	Q13315	ATM	S317	E320K	320	Missense	distal	3	no	16.627	16.916	EPSD	COSMIC	9.540	Up-regulation
Atypical_PIKK_ATM_ATM_ST	O14757	CHEK1	Q13315	ATM	S331	S326F	326	Missense	distal	-5	no	11.029	11.352	EPSD	COSMIC	9.540	Up-regulation
Atypical_PIKK_ATM_ATM_ST	O14757	CHEK1	Q13315	ATM	S331	P332L	332	Missense	proximal	1	no	11.029	9.474	EPSD	COSMIC	9.540	Loss
Atypical_PIKK_ATM_ATM_ST	O14757	CHEK1	Q13315	ATM	S333	S326F	326	Missense	distal	-7	no	11.340	10.511	EPSD	COSMIC	9.540	Down-regulation
Atypical_PIKK_ATM_ATM_ST	O14757	CHEK1	Q13315	ATM	S333	P332L	332	Missense	proximal	-1	no	11.340	11.497	EPSD	COSMIC	9.540	Up-regulation
Atypical_PIKK_ATM_ATM_ST	O14757	CHEK1	Q13315	ATM	S345	G341R	341	Missense	distal	-4	no	13.959	13.937	PhosphoSitePlus	COSMIC	9.540	Down-regulation
Atypical_PIKK_ATM_ATM_ST	O14757	CHEK1	Q13315	ATM	S345	F344L	344	Missense	proximal	-1	no	13.959	14.250	PhosphoSitePlus	COSMIC	9.540	Up-regulation
Atypical_PIKK_ATM_ATM_ST	O14757	CHEK1	Q13315	ATM	S345	H352Y	352	Missense	distal	7	no	13.959	13.964	PhosphoSitePlus	COSMIC	9.540	Up-regulation
Atypical_PIKK_ATM_ATM_ST	O14757	CHEK1	Q13315	ATM	S357	L360F	360	Missense	distal	3	no	11.736	12.036	EPSD	COSMIC	9.540	Up-regulation
Atypical_PIKK_ATM_ATM_ST	O14757	CHEK1	Q13315	ATM	S357	H352Y	352	Missense	distal	-5	no	11.736	11.711	EPSD	COSMIC	9.540	Down-regulation
Atypical_PIKK_ATM_ATM_ST	O14757	CHEK1	Q13315	ATM	S357	G361D	361	Missense	distal	4	no	11.736	11.815	EPSD	COSMIC;GDSC;CCLE	9.540	Up-regulation
Atypical_PIKK_ATM_ATM_ST	O14757	CHEK1	Q13315	ATM	S357	L354S	354	Missense	distal	-3	no	11.736	11.527	EPSD	COSMIC	9.540	Down-regulation
Atypical_PIKK_ATM_ATM_ST	O14757	CHEK1	Q13315	ATM	S366	L360F	360	Missense	distal	-6	no	14.062	13.819	EPSD	COSMIC	9.540	Down-regulation
Atypical_PIKK_ATM_ATM_ST	O14757	CHEK1	Q13315	ATM	S366	R372W	372	Missense	distal	6	no	14.062	14.030	EPSD	COSMIC	9.540	Down-regulation
Atypical_PIKK_ATM_ATM_ST	O14757	CHEK1	Q13315	ATM	S366	G361D	361	Missense	distal	-5	no	14.062	13.796	EPSD	COSMIC;GDSC;CCLE	9.540	Down-regulation
Atypical_PIKK_ATM_ATM_ST	O14757	CHEK1	Q13315	ATM	T417	V412A	412	Missense	distal	-5	no	10.594	10.473	EPSD	COSMIC	9.540	Down-regulation
Atypical_PIKK_ATM_ATM_ST	O14757	CHEK1	Q13315	ATM	S468	D464N	464	Missense	distal	-4	no	16.723	15.799	EPSD	COSMIC	9.540	Down-regulation
Atypical_PIKK_ATM_ATM_ST	O14757	CHEK1	Q13315	ATM	S468	K461N	461	Missense	distal	-7	no	16.723	16.849	EPSD	COSMIC	9.540	Up-regulation
Atypical_PIKK_ATM_ATM_ST	Q01844	EWSR1	Q13315	ATM	T79	T81S	81	Missense	proximal	2	no	11.160	11.422	PhosphoSitePlus	COSMIC	9.540	Up-regulation
Atypical_PIKK_ATM_ATM_ST	Q01844	EWSR1	Q13315	ATM	T79	T75A	75	Missense	distal	-4	no	11.160	11.034	PhosphoSitePlus	COSMIC	9.540	Down-regulation
Atypical_PIKK_ATM_ATM_ST	Q01844	EWSR1	Q13315	ATM	T79	P83H	83	Missense	distal	4	no	11.160	11.155	PhosphoSitePlus	COSMIC	9.540	Down-regulation
Atypical_PIKK_ATM_ATM_ST	Q01844	EWSR1	Q13315	ATM	T79	T78I	78	Missense	proximal	-1	no	11.160	10.930	PhosphoSitePlus	COSMIC	9.540	Down-regulation
Atypical_PIKK_ATM_ATM_ST	Q01844	EWSR1	Q13315	ATM	S416	P421S	421	Missense	distal	5	no	10.182	10.001	EPSD	COSMIC	9.540	Down-regulation
Atypical_PIKK_ATM_ATM_ST	Q01844	EWSR1	Q13315	ATM	S416	D412N	412	Missense	distal	-4	no	10.182	9.258	EPSD	COSMIC	9.540	Loss
Atypical_PIKK_ATM_ATM_ST	Q01844	EWSR1	Q13315	ATM	S416	T414A	414	Missense	proximal	-2	no	10.182	10.083	EPSD	COSMIC	9.540	Down-regulation
Atypical_PIKK_ATM_ATM_ST	Q16204	CCDC6	Q13315	ATM	S244	P242S	242	Missense	proximal	-2	no	10.292	10.528	EPSD	COSMIC	9.540	Up-regulation
Atypical_PIKK_ATM_ATM_ST	Q16204	CCDC6	Q13315	ATM	S244	V239A	239	Missense	distal	-5	no	10.292	10.171	EPSD	COSMIC;GDSC	9.540	Down-regulation
Atypical_PIKK_ATM_ATM_ST	Q16204	CCDC6	Q13315	ATM	S328	E324K	324	Missense	distal	-4	no	11.359	10.387	EPSD	COSMIC	9.540	Down-regulation
Atypical_PIKK_ATM_ATM_ST	Q16204	CCDC6	Q13315	ATM	S328	E334K	334	Missense	distal	6	no	11.359	11.314	EPSD	COSMIC	9.540	Down-regulation
Atypical_PIKK_ATM_ATM_ST	Q16204	CCDC6	Q13315	ATM	S419	R415W	415	Missense	distal	-4	no	13.282	12.806	EPSD	COSMIC	9.540	Down-regulation
Atypical_PIKK_ATM_ATM_ST	Q16204	CCDC6	Q13315	ATM	S419	P412H	412	Missense	distal	-7	no	13.282	13.205	EPSD	COSMIC	9.540	Down-regulation
Atypical_PIKK_ATM_ATM_ST	Q16204	CCDC6	Q13315	ATM	S419	R425Q	425	Missense	distal	6	no	13.282	13.277	EPSD	COSMIC	9.540	Down-regulation
Atypical_PIKK_ATM_ATM_ST	Q16204	CCDC6	Q13315	ATM	T434	P441S	441	Missense	distal	7	no	14.518	14.500	PhosphoSitePlus	COSMIC	9.540	Down-regulation
Atypical_PIKK_ATM_ATM_ST	Q16204	CCDC6	Q13315	ATM	T434	S431F	431	Missense	distal	-3	no	14.518	15.590	PhosphoSitePlus	COSMIC	9.540	Up-regulation
Atypical_PIKK_ATM_ATM_ST	Q16204	CCDC6	Q13315	ATM	S459	T462A	462	Missense	distal	3	no	13.636	13.611	EPSD	COSMIC	9.540	Down-regulation
Atypical_PIKK_ATM_ATM_ST	Q16204	CCDC6	Q13315	ATM	S459	P463S	463	Missense	distal	4	no	13.636	13.513	EPSD	COSMIC	9.540	Down-regulation
Atypical_PIKK_ATM_ATM_ST	Q16204	CCDC6	Q13315	ATM	S459	T452M	452	Missense	distal	-7	no	13.636	13.242	EPSD	COSMIC	9.540	Down-regulation
Atypical_PIKK_ATM_ATM_ST	Q16204	CCDC6	Q13315	ATM	S464	T462A	462	Missense	proximal	-2	no	14.429	14.329	EPSD	COSMIC	9.540	Down-regulation
Atypical_PIKK_ATM_ATM_ST	Q16204	CCDC6	Q13315	ATM	S464	S467L	467	Missense	distal	3	no	14.429	14.711	EPSD	COSMIC	9.540	Up-regulation
Atypical_PIKK_ATM_ATM_ST	Q16204	CCDC6	Q13315	ATM	S464	P463S	463	Missense	proximal	-1	no	14.429	14.721	EPSD	COSMIC	9.540	Up-regulation
Atypical_PIKK_ATM_ATM_ST	Q16204	CCDC6	Q13315	ATM	S472	S467L	467	Missense	distal	-5	no	16.050	16.073	EPSD	COSMIC	9.540	Up-regulation
Atypical_PIKK_ATM_ATM_ST	Q13098	GPS1	Q13315	ATM	S240	T242S	242	Missense	proximal	2	no	14.388	14.650	EPSD	COSMIC	9.540	Up-regulation
Atypical_PIKK_ATM_ATM_ST	Q13098	GPS1	Q13315	ATM	S240	T247S	247	Missense	distal	7	no	14.388	14.372	EPSD	COSMIC	9.540	Down-regulation
Atypical_PIKK_ATM_ATM_ST	Q13098	GPS1	Q13315	ATM	S240	D239G	239	Missense	proximal	-1	no	14.388	14.251	EPSD	COSMIC	9.540	Down-regulation
Atypical_PIKK_ATM_ATM_ST	Q13098	GPS1	Q13315	ATM	T242	T247S	247	Missense	distal	5	no	15.141	15.158	EPSD	COSMIC	9.540	Up-regulation
Atypical_PIKK_ATM_ATM_ST	Q13098	GPS1	Q13315	ATM	T242	D239G	239	Missense	distal	-3	no	15.141	15.173	EPSD	COSMIC	9.540	Up-regulation
Atypical_PIKK_ATM_ATM_ST	Q13098	GPS1	Q13315	ATM	T367	V362M	362	Missense	distal	-5	no	13.000	12.972	EPSD	COSMIC	9.540	Down-regulation
Atypical_PIKK_ATM_ATM_ST	Q13098	GPS1	Q13315	ATM	T367	L365M	365	Missense	proximal	-2	no	13.000	12.952	EPSD	COSMIC	9.540	Down-regulation
Atypical_PIKK_ATM_ATM_ST	Q13098	GPS1	Q13315	ATM	T367	Y366H	366	Missense	proximal	-1	no	13.000	12.845	EPSD	COSMIC	9.540	Down-regulation
Atypical_PIKK_ATM_ATM_ST	Q13098	GPS1	Q13315	ATM	T367	R372H	372	Missense	distal	5	no	13.000	12.975	EPSD	COSMIC	9.540	Down-regulation
Atypical_PIKK_ATM_ATM_ST	Q13098	GPS1	Q13315	ATM	T367	R370H	370	Missense	distal	3	no	13.000	13.038	EPSD	COSMIC	9.540	Up-regulation
Atypical_PIKK_ATM_ATM_ST	Q13098	GPS1	Q13315	ATM	T367	R370C	370	Missense	distal	3	no	13.000	13.236	EPSD	COSMIC	9.540	Up-regulation
Atypical_PIKK_ATM_ATM_ST	Q13098	GPS1	Q13315	ATM	S474	E472Q	472	Missense	proximal	-2	no	13.129	12.824	PhosphoSitePlus	COSMIC	9.540	Down-regulation
Atypical_PIKK_ATM_ATM_ST	Q13098	GPS1	Q13315	ATM	S474	S468T	468	Missense	distal	-6	no	13.129	13.060	PhosphoSitePlus	COSMIC	9.540	Down-regulation
Atypical_PIKK_ATM_ATM_ST	Q13098	GPS1	Q13315	ATM	S474	L478P	478	Missense	distal	4	no	13.129	12.910	PhosphoSitePlus	COSMIC	9.540	Down-regulation
Atypical_PIKK_ATM_ATM_ST	Q13098	GPS1	Q13315	ATM	T479	E472Q	472	Missense	distal	-7	no	10.907	10.352	EPSD	COSMIC	9.540	Down-regulation
Atypical_PIKK_ATM_ATM_ST	Q13098	GPS1	Q13315	ATM	T479	L478P	478	Missense	proximal	-1	no	10.907	10.750	EPSD	COSMIC	9.540	Down-regulation
Atypical_PIKK_ATM_ATM_ST	Q13098	GPS1	Q13315	ATM	T479	S483I	483	Missense	distal	4	no	10.907	11.570	EPSD	COSMIC	9.540	Up-regulation
Atypical_PIKK_ATM_ATM_ST	Q13098	GPS1	Q13315	ATM	S483	L478P	478	Missense	distal	-5	no	16.404	16.385	EPSD	COSMIC	9.540	Down-regulation
Atypical_PIKK_ATM_ATM_ST	Q13098	GPS1	Q13315	ATM	S483	S483I	483	Missense	central	0	yes	16.404	0.000	EPSD	COSMIC	9.540	Loss
Atypical_PIKK_ATM_ATM_ST	Q15109	AGER	Q13315	ATM	T195	R198W	198	Missense	distal	3	no	9.967	10.159	EPSD	COSMIC	9.540	Up-regulation
Atypical_PIKK_ATM_ATM_ST	Q15109	AGER	Q13315	ATM	T195	G199V	199	Missense	distal	4	no	9.967	10.144	EPSD	COSMIC	9.540	Up-regulation
Atypical_PIKK_ATM_ATM_ST	Q15109	AGER	Q13315	ATM	S391	E393K	393	Missense	proximal	2	no	11.086	9.755	PhosphoSitePlus	COSMIC	9.540	Down-regulation
Atypical_PIKK_ATM_ATM_ST	Q15109	AGER	Q13315	ATM	S391	E387K	387	Missense	distal	-4	no	11.086	10.114	PhosphoSitePlus	COSMIC	9.540	Down-regulation
Atypical_PIKK_ATM_ATM_ST	Q15109	AGER	Q13315	ATM	S391	E384G	384	Missense	distal	-7	no	11.086	10.218	PhosphoSitePlus	COSMIC	9.540	Down-regulation
Atypical_PIKK_ATM_ATM_ST	Q15109	AGER	Q13315	ATM	S391	N389S	389	Missense	proximal	-2	no	11.086	11.266	PhosphoSitePlus	COSMIC	9.540	Up-regulation
Atypical_PIKK_ATM_ATM_ST	Q15109	AGER	Q13315	ATM	S391	E387D	387	Missense	distal	-4	no	11.086	10.803	PhosphoSitePlus	COSMIC	9.540	Down-regulation
Atypical_PIKK_ATM_ATM_ST	Q15109	AGER	Q13315	ATM	S391	E398D	398	Missense	distal	7	no	11.086	11.099	PhosphoSitePlus	COSMIC	9.540	Up-regulation
Atypical_PIKK_ATM_ATM_ST	Q15109	AGER	Q13315	ATM	S391	L388M	388	Missense	distal	-3	no	11.086	11.232	PhosphoSitePlus	COSMIC;GDSC;CCLE	9.540	Up-regulation
Atypical_PIKK_ATM_ATM_ST	Q99638	RAD9A	Q13315	ATM	S272	S272C	272	Missense	central	0	yes	14.144	0.000	PhosphoSitePlus	COSMIC	9.540	Loss
Atypical_PIKK_ATM_ATM_ST	Q99638	RAD9A	Q13315	ATM	S272	S277T	277	Missense	distal	5	no	14.144	14.128	PhosphoSitePlus	COSMIC	9.540	Down-regulation
Atypical_PIKK_ATM_ATM_ST	Q99638	RAD9A	Q13315	ATM	S272	D269N	269	Missense	distal	-3	no	14.144	13.871	PhosphoSitePlus	COSMIC	9.540	Down-regulation
Atypical_PIKK_ATM_ATM_ST	Q99638	RAD9A	Q13315	ATM	T355	P349H	349	Missense	distal	-6	no	9.761	9.641	EPSD	COSMIC	9.540	Down-regulation
Atypical_PIKK_ATM_ATM_ST	P40692	MLH1	Q13315	ATM	S372	S369F	369	Missense	distal	-3	no	8.720	9.791	EPSD	COSMIC	9.540	Gain
Atypical_PIKK_ATM_ATM_ST	P40692	MLH1	Q13315	ATM	S388	V384D	384	Missense	distal	-4	no	9.388	10.373	EPSD	COSMIC;GDSC	9.540	Gain
Atypical_PIKK_ATM_ATM_ST	P40692	MLH1	Q13315	ATM	S388	R389Q	389	Missense	proximal	1	no	9.388	16.039	EPSD	COSMIC	9.540	Gain
Atypical_PIKK_ATM_ATM_ST	P40692	MLH1	Q13315	ATM	S388	V384G	384	Missense	distal	-4	no	9.388	9.589	EPSD	COSMIC	9.540	Gain
Atypical_PIKK_ATM_ATM_ST	P40692	MLH1	Q13315	ATM	S388	V384A	384	Missense	distal	-4	no	9.388	9.867	EPSD	COSMIC	9.540	Gain
Atypical_PIKK_ATM_ATM_ST	P40692	MLH1	Q13315	ATM	S406	S406N	406	Missense	central	0	yes	15.006	0.000	PhosphoSitePlus	COSMIC;GDSC	9.540	Loss
Atypical_PIKK_ATM_ATM_ST	P40692	MLH1	Q13315	ATM	S406	T413I	413	Missense	distal	7	no	15.006	15.021	PhosphoSitePlus	COSMIC	9.540	Up-regulation
Atypical_PIKK_ATM_ATM_ST	P40692	MLH1	Q13315	ATM	S406	S401N	401	Missense	distal	-5	no	15.006	14.978	PhosphoSitePlus	COSMIC	9.540	Down-regulation
Atypical_PIKK_ATM_ATM_ST	P40692	MLH1	Q13315	ATM	S406	V412L	412	Missense	distal	6	no	15.006	14.974	PhosphoSitePlus	COSMIC	9.540	Down-regulation
Atypical_PIKK_ATM_ATM_ST	P40692	MLH1	Q13315	ATM	S406	P399L	399	Missense	distal	-7	no	15.006	14.654	PhosphoSitePlus	COSMIC	9.540	Down-regulation
Atypical_PIKK_ATM_ATM_ST	P40692	MLH1	Q13315	ATM	S406	L400V	400	Missense	distal	-6	no	15.006	15.038	PhosphoSitePlus	COSMIC;GDSC;CCLE	9.540	Up-regulation
Atypical_PIKK_ATM_ATM_ST	P40692	MLH1	Q13315	ATM	S446	A441T	441	Missense	distal	-5	no	9.819	9.738	EPSD	COSMIC	9.540	Down-regulation
Atypical_PIKK_ATM_ATM_ST	P40692	MLH1	Q13315	ATM	S446	K443Q	443	Missense	distal	-3	no	9.819	9.876	EPSD	COSMIC	9.540	Up-regulation
Atypical_PIKK_ATM_ATM_ST	P40692	MLH1	Q13315	ATM	S446	V440M	440	Missense	distal	-6	no	9.819	9.831	EPSD	COSMIC	9.540	Up-regulation
Atypical_PIKK_ATM_ATM_ST	P40692	MLH1	Q13315	ATM	S486	R487Q	487	Missense	proximal	1	no	6.759	13.410	EPSD	COSMIC	9.540	Gain
Atypical_PIKK_ATM_ATM_ST	P40692	MLH1	Q13315	ATM	S692	R687W	687	Missense	distal	-5	no	10.216	10.381	EPSD	COSMIC	9.540	Up-regulation
Atypical_PIKK_ATM_ATM_ST	P40692	MLH1	Q13315	ATM	S692	L697I	697	Missense	distal	5	no	10.216	10.261	EPSD	COSMIC	9.540	Up-regulation
Atypical_PIKK_ATM_ATM_ST	P40692	MLH1	Q13315	ATM	S692	R687Q	687	Missense	distal	-5	no	10.216	10.006	EPSD	COSMIC	9.540	Down-regulation
Atypical_PIKK_ATM_ATM_ST	P40692	MLH1	Q13315	ATM	S692	I691K	691	Missense	proximal	-1	no	10.216	10.244	EPSD	COSMIC	9.540	Up-regulation
Atypical_PIKK_ATM_ATM_ST	P40692	MLH1	Q13315	ATM	S692	Y690C	690	Missense	proximal	-2	no	10.216	9.923	EPSD	COSMIC	9.540	Down-regulation
Atypical_PIKK_ATM_ATM_ST	P40692	MLH1	Q13315	ATM	S692	S698L	698	Missense	distal	6	no	10.216	10.159	EPSD	COSMIC	9.540	Down-regulation
Atypical_PIKK_ATM_ATM_ST	O43683	BUB1	Q13315	ATM	S224	E218K	218	Missense	distal	-6	no	9.940	9.640	EPSD	COSMIC	9.540	Down-regulation
Atypical_PIKK_ATM_ATM_ST	O43683	BUB1	Q13315	ATM	S224	A226V	226	Missense	proximal	2	no	9.940	9.631	EPSD	COSMIC	9.540	Down-regulation
Atypical_PIKK_ATM_ATM_ST	O43683	BUB1	Q13315	ATM	S314	S314F	314	Missense	central	0	yes	14.746	0.000	PhosphoSitePlus	COSMIC	9.540	Loss
Atypical_PIKK_ATM_ATM_ST	O43683	BUB1	Q13315	ATM	S331	G326E	326	Missense	distal	-5	no	14.645	14.425	EPSD	COSMIC	9.540	Down-regulation
Atypical_PIKK_ATM_ATM_ST	O43683	BUB1	Q13315	ATM	S331	R324C	324	Missense	distal	-7	no	14.645	14.370	EPSD	COSMIC	9.540	Down-regulation
Atypical_PIKK_ATM_ATM_ST	O43683	BUB1	Q13315	ATM	S331	R324H	324	Missense	distal	-7	no	14.645	14.730	EPSD	COSMIC	9.540	Up-regulation
Atypical_PIKK_ATM_ATM_ST	O43683	BUB1	Q13315	ATM	S379	S381N	381	Missense	proximal	2	no	16.400	15.759	EPSD	COSMIC	9.540	Down-regulation
Atypical_PIKK_ATM_ATM_ST	O43683	BUB1	Q13315	ATM	T441	T441A	441	Missense	central	0	yes	9.809	0.000	EPSD	COSMIC	9.540	Loss
Atypical_PIKK_ATM_ATM_ST	O43683	BUB1	Q13315	ATM	T441	T441P	441	Missense	central	0	yes	9.809	0.000	EPSD	COSMIC;GDSC;CCLE	9.540	Loss
Atypical_PIKK_ATM_ATM_ST	O43683	BUB1	Q13315	ATM	S459	P458Q	458	Missense	proximal	-1	no	12.629	12.854	EPSD	COSMIC	9.540	Up-regulation
Atypical_PIKK_ATM_ATM_ST	O43683	BUB1	Q13315	ATM	S459	P460L	460	Missense	proximal	1	no	12.629	11.074	EPSD	COSMIC	9.540	Down-regulation
Atypical_PIKK_ATM_ATM_ST	O43683	BUB1	Q13315	ATM	S459	T461A	461	Missense	proximal	2	no	12.629	12.308	EPSD	COSMIC	9.540	Down-regulation
Atypical_PIKK_ATM_ATM_ST	O43683	BUB1	Q13315	ATM	S563	E568V	568	Missense	distal	5	no	9.492	9.875	EPSD	COSMIC	9.540	Gain
Atypical_PIKK_ATM_ATM_ST	O43683	BUB1	Q13315	ATM	S563	K566N	566	Missense	distal	3	no	9.492	9.580	EPSD	COSMIC	9.540	Gain
Atypical_PIKK_ATM_ATM_ST	O43683	BUB1	Q13315	ATM	T609	V616A	616	Missense	distal	7	no	11.186	11.168	EPSD	COSMIC	9.540	Down-regulation
Atypical_PIKK_ATM_ATM_ST	O43683	BUB1	Q13315	ATM	T609	A607V	607	Missense	proximal	-2	no	11.186	10.709	EPSD	COSMIC	9.540	Down-regulation
Atypical_PIKK_ATM_ATM_ST	O43683	BUB1	Q13315	ATM	T634	K631Q	631	Missense	distal	-3	no	13.650	13.707	EPSD	COSMIC	9.540	Up-regulation
Atypical_PIKK_ATM_ATM_ST	O43683	BUB1	Q13315	ATM	T634	A630E	630	Missense	distal	-4	no	13.650	14.438	EPSD	COSMIC	9.540	Up-regulation
Atypical_PIKK_ATM_ATM_ST	O43683	BUB1	Q13315	ATM	S655	P662L	662	Missense	distal	7	no	10.998	10.999	EPSD	COSMIC;GDSC	9.540	Up-regulation
Atypical_PIKK_ATM_ATM_ST	O43683	BUB1	Q13315	ATM	S679	A683T	683	Missense	distal	4	no	13.608	14.043	EPSD	COSMIC	9.540	Up-regulation
Atypical_PIKK_ATM_ATM_ST	O43683	BUB1	Q13315	ATM	S679	G684S	684	Missense	distal	5	no	13.608	13.430	EPSD	COSMIC	9.540	Down-regulation
Atypical_PIKK_ATM_ATM_ST	O43683	BUB1	Q13315	ATM	S679	R677H	677	Missense	proximal	-2	no	13.608	13.624	EPSD	COSMIC	9.540	Up-regulation
Atypical_PIKK_ATM_ATM_ST	O00213	APBB1	Q13315	ATM	S118	K111R	111	Missense	distal	-7	no	9.921	9.835	EPSD	COSMIC;CCLE	9.540	Down-regulation
Atypical_PIKK_ATM_ATM_ST	O00213	APBB1	Q13315	ATM	S205	S203I	203	Missense	proximal	-2	no	9.690	9.000	EPSD	COSMIC	9.540	Loss
Atypical_PIKK_ATM_ATM_ST	O00213	APBB1	Q13315	ATM	S205	S207N	207	Missense	proximal	2	no	9.690	9.048	EPSD	COSMIC	9.540	Loss
Atypical_PIKK_ATM_ATM_ST	O00213	APBB1	Q13315	ATM	S205	R200Q	200	Missense	distal	-5	no	9.690	9.480	EPSD	COSMIC	9.540	Loss
Atypical_PIKK_ATM_ATM_ST	O00213	APBB1	Q13315	ATM	S205	E201K	201	Missense	distal	-4	no	9.690	8.718	EPSD	COSMIC	9.540	Loss
Atypical_PIKK_ATM_ATM_ST	O00213	APBB1	Q13315	ATM	S289	E296V	296	Missense	distal	7	no	15.539	15.592	EPSD	COSMIC	9.540	Up-regulation
Atypical_PIKK_ATM_ATM_ST	O00213	APBB1	Q13315	ATM	S289	P283L	283	Missense	distal	-6	no	15.539	15.310	EPSD	COSMIC	9.540	Down-regulation
Atypical_PIKK_ATM_ATM_ST	O00213	APBB1	Q13315	ATM	S289	P288T	288	Missense	proximal	-1	no	15.539	15.842	EPSD	COSMIC	9.540	Up-regulation
Atypical_PIKK_ATM_ATM_ST	O00213	APBB1	Q13315	ATM	S289	S293I	293	Missense	distal	4	no	15.539	16.202	EPSD	COSMIC	9.540	Up-regulation
Atypical_PIKK_ATM_ATM_ST	O00213	APBB1	Q13315	ATM	S289	R285P	285	Missense	distal	-4	no	15.539	15.681	EPSD	COSMIC	9.540	Up-regulation
Atypical_PIKK_ATM_ATM_ST	O00213	APBB1	Q13315	ATM	S322	E328K	328	Missense	distal	6	no	9.628	9.583	EPSD	COSMIC	9.540	Down-regulation
Atypical_PIKK_ATM_ATM_ST	Q86U86	PBRM1	Q13315	ATM	S10	K4Q	4	Missense	distal	-6	no	10.980	11.056	EPSD	COSMIC	9.540	Up-regulation
Atypical_PIKK_ATM_ATM_ST	Q86U86	PBRM1	Q13315	ATM	S10	T9A	9	Missense	proximal	-1	no	10.980	10.809	EPSD	COSMIC	9.540	Down-regulation
Atypical_PIKK_ATM_ATM_ST	Q86U86	PBRM1	Q13315	ATM	S10	S12F	12	Missense	proximal	2	no	10.980	9.501	EPSD	COSMIC	9.540	Loss
Atypical_PIKK_ATM_ATM_ST	Q86U86	PBRM1	Q13315	ATM	S89	L94F	94	Missense	distal	5	no	13.544	13.685	EPSD	COSMIC	9.540	Up-regulation
Atypical_PIKK_ATM_ATM_ST	Q86U86	PBRM1	Q13315	ATM	S89	D93N	93	Missense	distal	4	no	13.544	13.463	EPSD	COSMIC	9.540	Down-regulation
Atypical_PIKK_ATM_ATM_ST	Q86U86	PBRM1	Q13315	ATM	S178	A180G	180	Missense	proximal	2	no	11.661	11.386	EPSD	COSMIC;CCLE	9.540	Down-regulation
Atypical_PIKK_ATM_ATM_ST	Q86U86	PBRM1	Q13315	ATM	S178	G171V	171	Missense	distal	-7	no	11.661	11.693	EPSD	COSMIC	9.540	Up-regulation
Atypical_PIKK_ATM_ATM_ST	Q86U86	PBRM1	Q13315	ATM	S178	G176A	176	Missense	proximal	-2	no	11.661	11.917	EPSD	COSMIC	9.540	Up-regulation
Atypical_PIKK_ATM_ATM_ST	Q86U86	PBRM1	Q13315	ATM	S178	V173L	173	Missense	distal	-5	no	11.661	11.571	EPSD	COSMIC	9.540	Down-regulation
Atypical_PIKK_ATM_ATM_ST	Q86U86	PBRM1	Q13315	ATM	S353	E354Q	354	Missense	proximal	1	no	4.762	10.659	EPSD	COSMIC	9.540	Gain
Atypical_PIKK_ATM_ATM_ST	Q86U86	PBRM1	Q13315	ATM	S371	G369E	369	Missense	proximal	-2	no	11.033	11.657	EPSD	COSMIC	9.540	Up-regulation
Atypical_PIKK_ATM_ATM_ST	Q86U86	PBRM1	Q13315	ATM	S371	S378F	378	Missense	distal	7	no	11.033	11.093	EPSD	COSMIC	9.540	Up-regulation
Atypical_PIKK_ATM_ATM_ST	Q86U86	PBRM1	Q13315	ATM	S371	R365H	365	Missense	distal	-6	no	11.033	11.034	EPSD	COSMIC	9.540	Up-regulation
Atypical_PIKK_ATM_ATM_ST	Q86U86	PBRM1	Q13315	ATM	S371	E367K	367	Missense	distal	-4	no	11.033	10.061	EPSD	COSMIC	9.540	Down-regulation
Atypical_PIKK_ATM_ATM_ST	Q86U86	PBRM1	Q13315	ATM	S371	E374Q	374	Missense	distal	3	no	11.033	11.292	EPSD	COSMIC	9.540	Up-regulation
Atypical_PIKK_ATM_ATM_ST	Q86U86	PBRM1	Q13315	ATM	S371	R365W	365	Missense	distal	-6	no	11.033	10.865	EPSD	COSMIC	9.540	Down-regulation
Atypical_PIKK_ATM_ATM_ST	Q86U86	PBRM1	Q13315	ATM	S371	E374K	374	Missense	distal	3	no	11.033	11.322	EPSD	COSMIC	9.540	Up-regulation
Atypical_PIKK_ATM_ATM_ST	Q86U86	PBRM1	Q13315	ATM	S413	H410Y	410	Missense	distal	-3	no	9.998	10.036	EPSD	COSMIC	9.540	Up-regulation
Atypical_PIKK_ATM_ATM_ST	Q86U86	PBRM1	Q13315	ATM	S413	D419G	419	Missense	distal	6	no	9.998	10.001	EPSD	COSMIC	9.540	Up-regulation
Atypical_PIKK_ATM_ATM_ST	Q86U86	PBRM1	Q13315	ATM	S413	D419H	419	Missense	distal	6	no	9.998	9.987	EPSD	COSMIC	9.540	Down-regulation
Atypical_PIKK_ATM_ATM_ST	Q86U86	PBRM1	Q13315	ATM	S502	S505F	505	Missense	distal	3	no	9.054	9.636	EPSD	COSMIC	9.540	Gain
Atypical_PIKK_ATM_ATM_ST	Q86U86	PBRM1	Q13315	ATM	S505	A510V	510	Missense	distal	5	no	9.405	9.570	EPSD	COSMIC	9.540	Gain
Atypical_PIKK_ATM_ATM_ST	Q86U86	PBRM1	Q13315	ATM	S605	G604D	604	Missense	proximal	-1	no	14.316	14.453	EPSD	COSMIC	9.540	Up-regulation
Atypical_PIKK_ATM_ATM_ST	Q86U86	PBRM1	Q13315	ATM	S605	E602K	602	Missense	distal	-3	no	14.316	14.383	EPSD	COSMIC	9.540	Up-regulation
Atypical_PIKK_ATM_ATM_ST	Q86U86	PBRM1	Q13315	ATM	S605	E602Q	602	Missense	distal	-3	no	14.316	14.440	EPSD	COSMIC	9.540	Up-regulation
Atypical_PIKK_ATM_ATM_ST	Q86U86	PBRM1	Q13315	ATM	S605	D610E	610	Missense	distal	5	no	14.316	14.059	EPSD	COSMIC	9.540	Down-regulation
Atypical_PIKK_ATM_ATM_ST	Q86U86	PBRM1	Q13315	ATM	S605	E603K	603	Missense	proximal	-2	no	14.316	13.740	EPSD	COSMIC	9.540	Down-regulation
Atypical_PIKK_ATM_ATM_ST	Q86U86	PBRM1	Q13315	ATM	S636	S636P	636	Missense	central	0	yes	10.096	0.000	EPSD	COSMIC	9.540	Loss
Atypical_PIKK_ATM_ATM_ST	Q86U86	PBRM1	Q13315	ATM	S636	D631N	631	Missense	distal	-5	no	10.096	10.279	EPSD	COSMIC	9.540	Up-regulation
Atypical_PIKK_ATM_ATM_ST	Q86U86	PBRM1	Q13315	ATM	S681	P688S	688	Missense	distal	7	no	11.273	11.255	EPSD	COSMIC	9.540	Down-regulation
Atypical_PIKK_ATM_ATM_ST	Q86U86	PBRM1	Q13315	ATM	S681	L685M	685	Missense	distal	4	no	11.273	11.192	EPSD	COSMIC	9.540	Down-regulation
Atypical_PIKK_ATM_ATM_ST	Q86U86	PBRM1	Q13315	ATM	S681	R679L	679	Missense	proximal	-2	no	11.273	11.327	EPSD	COSMIC	9.540	Up-regulation
Atypical_PIKK_ATM_ATM_ST	Q86U86	PBRM1	Q13315	ATM	S681	R678C	678	Missense	distal	-3	no	11.273	10.701	EPSD	COSMIC	9.540	Down-regulation
Atypical_PIKK_ATM_ATM_ST	Q86U86	PBRM1	Q13315	ATM	S681	F684Y	684	Missense	distal	3	no	11.273	10.933	EPSD	COSMIC	9.540	Down-regulation
Atypical_PIKK_ATM_ATM_ST	Q86U86	PBRM1	Q13315	ATM	S681	R678G	678	Missense	distal	-3	no	11.273	10.812	EPSD	COSMIC	9.540	Down-regulation
Atypical_PIKK_ATM_ATM_ST	Q86U86	PBRM1	Q13315	ATM	S681	R678Q	678	Missense	distal	-3	no	11.273	10.499	EPSD	COSMIC	9.540	Down-regulation
Atypical_PIKK_ATM_ATM_ST	Q86U86	PBRM1	Q13315	ATM	S681	R678P	678	Missense	distal	-3	no	11.273	10.730	EPSD	COSMIC	9.540	Down-regulation
Atypical_PIKK_ATM_ATM_ST	Q86U86	PBRM1	Q13315	ATM	S689	P688S	688	Missense	proximal	-1	no	10.047	10.339	EPSD	COSMIC	9.540	Up-regulation
Atypical_PIKK_ATM_ATM_ST	Q86U86	PBRM1	Q13315	ATM	S689	L685M	685	Missense	distal	-4	no	10.047	9.979	EPSD	COSMIC	9.540	Down-regulation
Atypical_PIKK_ATM_ATM_ST	Q86U86	PBRM1	Q13315	ATM	S689	E692Q	692	Missense	distal	3	no	10.047	10.306	EPSD	COSMIC	9.540	Up-regulation
Atypical_PIKK_ATM_ATM_ST	Q86U86	PBRM1	Q13315	ATM	S689	S689F	689	Missense	central	0	yes	10.047	0.000	EPSD	COSMIC	9.540	Loss
Atypical_PIKK_ATM_ATM_ST	Q86U86	PBRM1	Q13315	ATM	S689	F684Y	684	Missense	distal	-5	no	10.047	9.747	EPSD	COSMIC	9.540	Down-regulation
Atypical_PIKK_ATM_ATM_ST	Q86U86	PBRM1	Q13315	ATM	S689	D695E	695	Missense	distal	6	no	10.047	10.093	EPSD	COSMIC	9.540	Up-regulation
Atypical_PIKK_ATM_ATM_ST	Q86U86	PBRM1	Q13315	ATM	S691	E692Q	692	Missense	proximal	1	no	6.445	12.342	EPSD	COSMIC	9.540	Gain
Atypical_PIKK_ATM_ATM_ST	Q86U86	PBRM1	Q13315	ATM	S931	K930N	930	Missense	proximal	-1	no	12.608	12.745	EPSD	COSMIC	9.540	Up-regulation
Atypical_PIKK_ATM_ATM_ST	Q86U86	PBRM1	Q13315	ATM	S931	S934F	934	Missense	distal	3	no	12.608	13.190	EPSD	COSMIC	9.540	Up-regulation
Atypical_PIKK_ATM_ATM_ST	Q86U86	PBRM1	Q13315	ATM	S931	E929K	929	Missense	proximal	-2	no	12.608	12.032	EPSD	COSMIC	9.540	Down-regulation
Atypical_PIKK_ATM_ATM_ST	Q86U86	PBRM1	Q13315	ATM	S931	K925Q	925	Missense	distal	-6	no	12.608	12.684	EPSD	COSMIC;CCLE	9.540	Up-regulation
Atypical_PIKK_ATM_ATM_ST	Q86U86	PBRM1	Q13315	ATM	S935	K930N	930	Missense	distal	-5	no	9.702	9.758	EPSD	COSMIC	9.540	Up-regulation
Atypical_PIKK_ATM_ATM_ST	Q86U86	PBRM1	Q13315	ATM	S935	S934F	934	Missense	proximal	-1	no	9.702	9.275	EPSD	COSMIC	9.540	Loss
Atypical_PIKK_ATM_ATM_ST	Q86U86	PBRM1	Q13315	ATM	S935	E929K	929	Missense	distal	-6	no	9.702	9.401	EPSD	COSMIC	9.540	Loss
Atypical_PIKK_ATM_ATM_ST	Q86U86	PBRM1	Q13315	ATM	S948	L943S	943	Missense	distal	-5	no	16.582	16.560	PhosphoSitePlus	COSMIC	9.540	Down-regulation
Atypical_PIKK_ATM_ATM_ST	Q86U86	PBRM1	Q13315	ATM	S948	R945H	945	Missense	distal	-3	no	16.582	15.937	PhosphoSitePlus	COSMIC	9.540	Down-regulation
Atypical_PIKK_ATM_ATM_ST	Q86U86	PBRM1	Q13315	ATM	S1116	N1112S	1112	Missense	distal	-4	no	10.171	11.100	EPSD	COSMIC	9.540	Up-regulation
Atypical_PIKK_ATM_ATM_ST	Q86U86	PBRM1	Q13315	ATM	S1116	E1117G	1117	Missense	proximal	1	no	10.171	9.594	EPSD	COSMIC	9.540	Down-regulation
Atypical_PIKK_ATM_ATM_ST	Q86U86	PBRM1	Q13315	ATM	S1116	E1110G	1110	Missense	distal	-6	no	10.171	9.782	EPSD	COSMIC	9.540	Down-regulation
Atypical_PIKK_ATM_ATM_ST	Q86U86	PBRM1	Q13315	ATM	S1280	D1285V	1285	Missense	distal	5	no	12.779	12.905	EPSD	COSMIC	9.540	Up-regulation
Atypical_PIKK_ATM_ATM_ST	Q86U86	PBRM1	Q13315	ATM	S1280	V1283E	1283	Missense	distal	3	no	12.779	12.259	EPSD	COSMIC	9.540	Down-regulation
Atypical_PIKK_ATM_ATM_ST	Q86U86	PBRM1	Q13315	ATM	S1280	S1280P	1280	Missense	central	0	yes	12.779	0.000	EPSD	COSMIC	9.540	Loss
Atypical_PIKK_ATM_ATM_ST	Q86U86	PBRM1	Q13315	ATM	S1280	A1281V	1281	Missense	proximal	1	no	12.779	6.657	EPSD	COSMIC	9.540	Loss
Atypical_PIKK_ATM_ATM_ST	Q86U86	PBRM1	Q13315	ATM	S1280	G1273A	1273	Missense	distal	-7	no	12.779	13.195	EPSD	COSMIC	9.540	Up-regulation
Atypical_PIKK_ATM_ATM_ST	Q86U86	PBRM1	Q13315	ATM	S1280	F1277Y	1277	Missense	distal	-3	no	12.779	11.840	EPSD	COSMIC	9.540	Down-regulation
Atypical_PIKK_ATM_ATM_ST	Q86U86	PBRM1	Q13315	ATM	S1453	A1452V	1452	Missense	proximal	-1	no	9.845	9.583	EPSD	COSMIC	9.540	Down-regulation
Atypical_PIKK_ATM_ATM_ST	Q86U86	PBRM1	Q13315	ATM	S1453	P1459L	1459	Missense	distal	6	no	9.845	9.800	EPSD	COSMIC	9.540	Down-regulation
Atypical_PIKK_ATM_ATM_ST	Q86U86	PBRM1	Q13315	ATM	S1453	V1460A	1460	Missense	distal	7	no	9.845	9.828	EPSD	COSMIC	9.540	Down-regulation
Atypical_PIKK_ATM_ATM_ST	Q99504	EYA3	Q13315	ATM	S256	Q252R	252	Missense	distal	-4	no	10.141	9.775	EPSD	COSMIC	9.540	Down-regulation
Atypical_PIKK_ATM_ATM_ST	Q99504	EYA3	Q13315	ATM	S256	G257V	257	Missense	proximal	1	no	10.141	3.620	EPSD	COSMIC	9.540	Loss
Atypical_PIKK_ATM_ATM_ST	Q99504	EYA3	Q13315	ATM	S256	Q252H	252	Missense	distal	-4	no	10.141	9.906	EPSD	COSMIC	9.540	Down-regulation
Atypical_PIKK_ATM_ATM_ST	Q99504	EYA3	Q13315	ATM	S256	D258Y	258	Missense	proximal	2	no	10.141	8.900	EPSD	COSMIC	9.540	Loss
Atypical_PIKK_ATM_ATM_ST	Q99504	EYA3	Q13315	ATM	S262	G257V	257	Missense	distal	-5	no	10.966	11.024	EPSD	COSMIC	9.540	Up-regulation
Atypical_PIKK_ATM_ATM_ST	Q99504	EYA3	Q13315	ATM	S262	D258Y	258	Missense	distal	-4	no	10.966	9.869	EPSD	COSMIC	9.540	Down-regulation
Atypical_PIKK_ATM_ATM_ST	Q99504	EYA3	Q13315	ATM	S264	G257V	257	Missense	distal	-7	no	10.559	10.591	EPSD	COSMIC	9.540	Up-regulation
Atypical_PIKK_ATM_ATM_ST	Q99504	EYA3	Q13315	ATM	S264	D258Y	258	Missense	distal	-6	no	10.559	10.337	EPSD	COSMIC	9.540	Down-regulation
Atypical_PIKK_ATM_ATM_ST	Q99504	EYA3	Q13315	ATM	S297	D299Y	299	Missense	proximal	2	no	16.215	14.974	EPSD	COSMIC;GDSC;CCLE	9.540	Down-regulation
Atypical_PIKK_ATM_ATM_ST	Q99504	EYA3	Q13315	ATM	S438	A444T	444	Missense	distal	6	no	11.421	11.405	EPSD	COSMIC	9.540	Down-regulation
Atypical_PIKK_ATM_ATM_ST	Q99504	EYA3	Q13315	ATM	S438	N432I	432	Missense	distal	-6	no	11.421	11.136	EPSD	COSMIC	9.540	Down-regulation
Atypical_PIKK_ATM_ATM_ST	Q8TAQ2	SMARCC2	Q13315	ATM	S302	P305S	305	Missense	distal	3	no	9.542	9.390	EPSD	COSMIC	9.540	Loss
Atypical_PIKK_ATM_ATM_ST	Q8TAQ2	SMARCC2	Q13315	ATM	S302	P307L	307	Missense	distal	5	no	9.542	9.525	EPSD	COSMIC	9.540	Loss
Atypical_PIKK_ATM_ATM_ST	Q8TAQ2	SMARCC2	Q13315	ATM	S304	P305S	305	Missense	proximal	1	no	10.849	3.874	EPSD	COSMIC	9.540	Loss
Atypical_PIKK_ATM_ATM_ST	Q8TAQ2	SMARCC2	Q13315	ATM	S304	P307L	307	Missense	distal	3	no	10.849	10.979	EPSD	COSMIC	9.540	Up-regulation
Atypical_PIKK_ATM_ATM_ST	Q8TAQ2	SMARCC2	Q13315	ATM	S306	P305S	305	Missense	proximal	-1	no	9.367	9.659	EPSD	COSMIC	9.540	Gain
Atypical_PIKK_ATM_ATM_ST	Q8TAQ2	SMARCC2	Q13315	ATM	T308	P305S	305	Missense	distal	-3	no	10.631	10.434	EPSD	COSMIC	9.540	Down-regulation
Atypical_PIKK_ATM_ATM_ST	Q8TAQ2	SMARCC2	Q13315	ATM	T308	P307L	307	Missense	proximal	-1	no	10.631	10.788	EPSD	COSMIC	9.540	Up-regulation
Atypical_PIKK_ATM_ATM_ST	Q8TAQ2	SMARCC2	Q13315	ATM	S369	S369L	369	Missense	central	0	yes	9.822	0.000	EPSD	COSMIC	9.540	Loss
Atypical_PIKK_ATM_ATM_ST	Q8TAQ2	SMARCC2	Q13315	ATM	T458	G452S	452	Missense	distal	-6	no	11.079	11.281	EPSD	COSMIC	9.540	Up-regulation
Atypical_PIKK_ATM_ATM_ST	Q8TAQ2	SMARCC2	Q13315	ATM	T458	A464G	464	Missense	distal	6	no	11.079	11.054	EPSD	COSMIC	9.540	Down-regulation
Atypical_PIKK_ATM_ATM_ST	Q8TAQ2	SMARCC2	Q13315	ATM	T458	G452D	452	Missense	distal	-6	no	11.079	11.254	EPSD	COSMIC;GDSC;CCLE	9.540	Up-regulation
Atypical_PIKK_ATM_ATM_ST	Q8TAQ2	SMARCC2	Q13315	ATM	T458	N451I	451	Missense	distal	-7	no	11.079	10.601	EPSD	COSMIC	9.540	Down-regulation
Atypical_PIKK_ATM_ATM_ST	Q8TAQ2	SMARCC2	Q13315	ATM	T458	Y465H	465	Missense	distal	7	no	11.079	11.074	EPSD	COSMIC	9.540	Down-regulation
Atypical_PIKK_ATM_ATM_ST	Q8TAQ2	SMARCC2	Q13315	ATM	S555	M558T	558	Missense	distal	3	no	14.022	13.847	EPSD	COSMIC	9.540	Down-regulation
Atypical_PIKK_ATM_ATM_ST	Q8TAQ2	SMARCC2	Q13315	ATM	S745	R750W	750	Missense	distal	5	no	10.783	10.807	EPSD	COSMIC	9.540	Up-regulation
Atypical_PIKK_ATM_ATM_ST	Q8TAQ2	SMARCC2	Q13315	ATM	S969	G968C	968	Missense	proximal	-1	no	13.793	13.785	PhosphoSitePlus	COSMIC	9.540	Down-regulation
Atypical_PIKK_ATM_ATM_ST	Q8TAQ2	SMARCC2	Q13315	ATM	S969	G968V	968	Missense	proximal	-1	no	13.793	13.561	PhosphoSitePlus	COSMIC	9.540	Down-regulation
Atypical_PIKK_ATM_ATM_ST	Q8TAQ2	SMARCC2	Q13315	ATM	S969	Q970K	970	Missense	proximal	1	no	13.793	6.945	PhosphoSitePlus	COSMIC	9.540	Loss
Atypical_PIKK_ATM_ATM_ST	Q8TAQ2	SMARCC2	Q13315	ATM	S969	S969F	969	Missense	central	0	yes	13.793	0.000	PhosphoSitePlus	COSMIC	9.540	Loss
Atypical_PIKK_ATM_ATM_ST	Q15797	SMAD1	Q13315	ATM	S132	V130L	130	Missense	proximal	-2	no	9.442	9.717	EPSD	COSMIC	9.540	Gain
Atypical_PIKK_ATM_ATM_ST	Q15797	SMAD1	Q13315	ATM	S195	P188S	188	Missense	distal	-7	no	9.488	9.724	EPSD	COSMIC	9.540	Gain
Atypical_PIKK_ATM_ATM_ST	Q15797	SMAD1	Q13315	ATM	S239	P241L	241	Missense	proximal	2	no	14.556	13.767	PhosphoSitePlus	COSMIC	9.540	Down-regulation
Atypical_PIKK_ATM_ATM_ST	Q15797	SMAD1	Q13315	ATM	S239	G238D	238	Missense	proximal	-1	no	14.556	14.694	PhosphoSitePlus	COSMIC	9.540	Up-regulation
Atypical_PIKK_ATM_ATM_ST	Q15797	SMAD1	Q13315	ATM	S239	M242I	242	Missense	distal	3	no	14.556	14.802	PhosphoSitePlus	COSMIC	9.540	Up-regulation
Atypical_PIKK_ATM_ATM_ST	Q15797	SMAD1	Q13315	ATM	T452	Q445L	445	Missense	distal	-7	no	10.635	10.247	EPSD	COSMIC	9.540	Down-regulation
Atypical_PIKK_ATM_ATM_ST	P55072	VCP	Q13315	ATM	S457	R453W	453	Missense	distal	-4	no	16.110	15.634	EPSD	COSMIC	9.540	Down-regulation
Atypical_PIKK_ATM_ATM_ST	P55072	VCP	Q13315	ATM	S457	L456V	456	Missense	proximal	-1	no	16.110	15.821	EPSD	COSMIC	9.540	Down-regulation
Atypical_PIKK_ATM_ATM_ST	P55072	VCP	Q13315	ATM	S705	S702F	702	Missense	distal	-3	no	8.584	9.656	EPSD	COSMIC	9.540	Gain
Atypical_PIKK_ATM_ATM_ST	P55072	VCP	Q13315	ATM	S765	R766Q	766	Missense	proximal	1	no	8.124	14.776	EPSD	COSMIC;CCLE	9.540	Gain
Atypical_PIKK_ATM_ATM_ST	P55072	VCP	Q13315	ATM	S784	T791P	791	Missense	distal	7	no	11.612	11.614	EPSD	COSMIC	9.540	Up-regulation
Atypical_PIKK_ATM_ATM_ST	P50542	PEX5	Q13315	ATM	S141	F144I	144	Missense	distal	3	no	16.284	16.204	PhosphoSitePlus	COSMIC	9.540	Down-regulation
Atypical_PIKK_ATM_ATM_ST	P50542	PEX5	Q13315	ATM	S141	D139N	139	Missense	proximal	-2	no	16.284	16.403	PhosphoSitePlus	COSMIC	9.540	Up-regulation
Atypical_PIKK_ATM_ATM_ST	P50542	PEX5	Q13315	ATM	S141	F144L	144	Missense	distal	3	no	16.284	15.984	PhosphoSitePlus	COSMIC	9.540	Down-regulation
Atypical_PIKK_ATM_ATM_ST	P50542	PEX5	Q13315	ATM	S155	A160S	160	Missense	distal	5	no	10.810	10.762	EPSD	COSMIC	9.540	Down-regulation
Atypical_PIKK_ATM_ATM_ST	P50542	PEX5	Q13315	ATM	S155	R158C	158	Missense	distal	3	no	10.810	11.045	EPSD	COSMIC	9.540	Up-regulation
Atypical_PIKK_ATM_ATM_ST	P50542	PEX5	Q13315	ATM	S155	P151T	151	Missense	distal	-4	no	10.810	11.096	EPSD	COSMIC	9.540	Up-regulation
Atypical_PIKK_ATM_ATM_ST	P50542	PEX5	Q13315	ATM	S155	D150G	150	Missense	distal	-5	no	10.810	11.075	EPSD	COSMIC	9.540	Up-regulation
Atypical_PIKK_ATM_ATM_ST	P50542	PEX5	Q13315	ATM	S167	A160S	160	Missense	distal	-7	no	11.984	12.081	EPSD	COSMIC	9.540	Up-regulation
Atypical_PIKK_ATM_ATM_ST	P50542	PEX5	Q13315	ATM	S228	G225E	225	Missense	distal	-3	no	10.826	10.388	EPSD	COSMIC	9.540	Down-regulation
Atypical_PIKK_ATM_ATM_ST	P50542	PEX5	Q13315	ATM	S228	E224K	224	Missense	distal	-4	no	10.826	9.854	EPSD	COSMIC	9.540	Down-regulation
Atypical_PIKK_ATM_ATM_ST	P50542	PEX5	Q13315	ATM	S228	S231C	231	Missense	distal	3	no	10.826	11.247	EPSD	COSMIC	9.540	Up-regulation
Atypical_PIKK_ATM_ATM_ST	P50542	PEX5	Q13315	ATM	S228	G223D	223	Missense	distal	-5	no	10.826	10.561	EPSD	COSMIC	9.540	Down-regulation
Atypical_PIKK_ATM_ATM_ST	P50542	PEX5	Q13315	ATM	S228	S228F	228	Missense	central	0	yes	10.826	0.000	EPSD	COSMIC;CCLE	9.540	Loss
Atypical_PIKK_ATM_ATM_ST	P50542	PEX5	Q13315	ATM	S310	D314V	314	Missense	distal	4	no	9.965	10.063	EPSD	COSMIC	9.540	Up-regulation
Atypical_PIKK_ATM_ATM_ST	P50542	PEX5	Q13315	ATM	S310	H306Y	306	Missense	distal	-4	no	9.965	9.544	EPSD	COSMIC	9.540	Down-regulation
Atypical_PIKK_ATM_ATM_ST	P50542	PEX5	Q13315	ATM	S310	Y312N	312	Missense	proximal	2	no	9.965	10.184	EPSD	COSMIC	9.540	Up-regulation
Atypical_PIKK_ATM_ATM_ST	P50542	PEX5	Q13315	ATM	S310	E304K	304	Missense	distal	-6	no	9.965	9.664	EPSD	COSMIC	9.540	Down-regulation
Atypical_PIKK_ATM_ATM_ST	P50542	PEX5	Q13315	ATM	S310	P307H	307	Missense	distal	-3	no	9.965	9.863	EPSD	COSMIC;CCLE	9.540	Down-regulation
Atypical_PIKK_ATM_ATM_ST	P50542	PEX5	Q13315	ATM	S317	K322T	322	Missense	distal	5	no	9.650	9.630	EPSD	COSMIC	9.540	Down-regulation
Atypical_PIKK_ATM_ATM_ST	P50542	PEX5	Q13315	ATM	S317	D314V	314	Missense	distal	-3	no	9.650	9.823	EPSD	COSMIC	9.540	Up-regulation
Atypical_PIKK_ATM_ATM_ST	P50542	PEX5	Q13315	ATM	S317	A318S	318	Missense	proximal	1	no	9.650	4.747	EPSD	COSMIC	9.540	Loss
Atypical_PIKK_ATM_ATM_ST	P50542	PEX5	Q13315	ATM	S317	Y312N	312	Missense	distal	-5	no	9.650	9.599	EPSD	COSMIC	9.540	Down-regulation
Atypical_PIKK_ATM_ATM_ST	P50542	PEX5	Q13315	ATM	S538	E540G	540	Missense	proximal	2	no	10.173	8.804	EPSD	COSMIC	9.540	Loss
Atypical_PIKK_ATM_ATM_ST	P50542	PEX5	Q13315	ATM	S538	A543V	543	Missense	distal	5	no	10.173	10.337	EPSD	COSMIC;CCLE	9.540	Up-regulation
Atypical_PIKK_ATM_ATM_ST	P50542	PEX5	Q13315	ATM	S538	Y545H	545	Missense	distal	7	no	10.173	10.168	EPSD	COSMIC	9.540	Down-regulation
Atypical_PIKK_ATM_ATM_ST	P50542	PEX5	Q13315	ATM	S538	A544V	544	Missense	distal	6	no	10.173	10.143	EPSD	COSMIC	9.540	Down-regulation
Atypical_PIKK_ATM_ATM_ST	P50542	PEX5	Q13315	ATM	S538	A544T	544	Missense	distal	6	no	10.173	10.157	EPSD	COSMIC	9.540	Down-regulation
Atypical_PIKK_ATM_ATM_ST	P50542	PEX5	Q13315	ATM	S538	L532F	532	Missense	distal	-6	no	10.173	9.930	EPSD	COSMIC	9.540	Down-regulation
Atypical_PIKK_ATM_ATM_ST	P50542	PEX5	Q13315	ATM	S538	E540Q	540	Missense	proximal	2	no	10.173	9.360	EPSD	COSMIC	9.540	Loss
TK_Trk_NTRK1_Y	P35222	CTNNB1	P04629	NTRK1	Y30	Y30C	30	Missense	central	0	yes	0.000	0.000	EPSD	COSMIC	0.000	Loss
TK_Trk_NTRK1_Y	P35222	CTNNB1	P04629	NTRK1	Y30	Y30S	30	Missense	central	0	yes	0.000	0.000	EPSD	COSMIC	0.000	Loss
TK_Trk_NTRK1_Y	P35222	CTNNB1	P04629	NTRK1	Y86	Y86H	86	Missense	central	0	yes	0.000	0.000	EPSD	COSMIC	0.000	Loss
TK_Trk_NTRK1_Y	P35222	CTNNB1	P04629	NTRK1	Y716	Y716C	716	Missense	central	0	yes	0.000	0.000	EPSD	COSMIC	0.000	Loss
TK_Trk_NTRK1_Y	P35222	CTNNB1	P04629	NTRK1	Y724	Y724S	724	Missense	central	0	yes	0.000	0.000	EPSD	COSMIC	0.000	Loss
TK_Trk_NTRK1_Y	P35222	CTNNB1	P04629	NTRK1	Y724	Y724C	724	Missense	central	0	yes	0.000	0.000	EPSD	COSMIC	0.000	Loss
TK_Trk_NTRK1_Y	P04629	NTRK1	P04629	NTRK1	Y640	Y640C	640	Missense	central	0	yes	0.000	0.000	EPSD	COSMIC	0.000	Loss
TK_Trk_NTRK1_Y	P04629	NTRK1	P04629	NTRK1	Y729	Y729H	729	Missense	central	0	yes	0.000	0.000	EPSD	COSMIC	0.000	Loss
CMGC_MAPK_p38_MAPK13_ST	O00418	EEF2K	O15264	MAPK13	S61	V56L	56	Missense	distal	-5	no	39.058	39.269	EPSD	COSMIC	38.013	Up-regulation
CMGC_MAPK_p38_MAPK13_ST	O00418	EEF2K	O15264	MAPK13	S359	T364N	364	Missense	distal	5	no	53.316	53.042	EPSD;PhosphoSitePlus	COSMIC	38.013	Down-regulation
CMGC_MAPK_p38_MAPK13_ST	O00418	EEF2K	O15264	MAPK13	S359	E355K	355	Missense	distal	-4	no	53.316	55.764	EPSD;PhosphoSitePlus	COSMIC	38.013	Up-regulation
CMGC_MAPK_p38_MAPK13_ST	O00418	EEF2K	O15264	MAPK13	S396	S398C	398	Missense	proximal	2	no	51.905	49.317	PhosphoSitePlus;EPSD	COSMIC	38.013	Down-regulation
CMGC_MAPK_p38_MAPK13_ST	O00418	EEF2K	O15264	MAPK13	S396	T389I	389	Missense	distal	-7	no	51.905	48.987	PhosphoSitePlus;EPSD	COSMIC	38.013	Down-regulation
CMGC_MAPK_p38_MAPK13_ST	O00418	EEF2K	O15264	MAPK13	S396	S399L	399	Missense	distal	3	no	51.905	51.450	PhosphoSitePlus;EPSD	COSMIC	38.013	Down-regulation
CMGC_MAPK_p38_MAPK13_ST	O00418	EEF2K	O15264	MAPK13	S396	P394L	394	Missense	proximal	-2	no	51.905	50.375	PhosphoSitePlus;EPSD	COSMIC;GDSC;CCLE	38.013	Down-regulation
CMGC_MAPK_p38_MAPK13_ST	O00418	EEF2K	O15264	MAPK13	S396	P394S	394	Missense	proximal	-2	no	51.905	51.199	PhosphoSitePlus;EPSD	COSMIC	38.013	Down-regulation
CMGC_MAPK_p38_MAPK13_ST	O00418	EEF2K	O15264	MAPK13	T401	S398C	398	Missense	distal	-3	no	46.484	44.398	EPSD	COSMIC	38.013	Down-regulation
CMGC_MAPK_p38_MAPK13_ST	O00418	EEF2K	O15264	MAPK13	T401	S399L	399	Missense	proximal	-2	no	46.484	45.660	EPSD	COSMIC	38.013	Down-regulation
CMGC_MAPK_p38_MAPK13_ST	O00418	EEF2K	O15264	MAPK13	T401	P394L	394	Missense	distal	-7	no	46.484	46.647	EPSD	COSMIC;GDSC;CCLE	38.013	Up-regulation
CMGC_MAPK_p38_MAPK13_ST	O00418	EEF2K	O15264	MAPK13	T401	P394S	394	Missense	distal	-7	no	46.484	47.904	EPSD	COSMIC	38.013	Up-regulation
CMGC_MAPK_p38_MAPK13_ST	O00418	EEF2K	O15264	MAPK13	S404	S398C	398	Missense	distal	-6	no	47.258	45.723	EPSD	COSMIC	38.013	Down-regulation
CMGC_MAPK_p38_MAPK13_ST	O00418	EEF2K	O15264	MAPK13	S404	S399L	399	Missense	distal	-5	no	47.258	47.855	EPSD	COSMIC	38.013	Up-regulation
CMGC_MAPK_p38_MAPK13_ST	O00418	EEF2K	O15264	MAPK13	S627	S622Y	622	Missense	distal	-5	no	37.639	38.218	EPSD	COSMIC	38.013	Gain
CMGC_MAPK_p38_MAPK13_ST	O00418	EEF2K	O15264	MAPK13	S627	C631R	631	Missense	distal	4	no	37.639	39.151	EPSD	COSMIC	38.013	Gain
CMGC_MAPK_p38_MAPK13_ST	P10636	MAPT	O15264	MAPK13	T69	E62K	62	Missense	distal	-7	no	55.747	55.933	EPSD	COSMIC	38.013	Up-regulation
CMGC_MAPK_p38_MAPK13_ST	P10636	MAPT	O15264	MAPK13	T111	I108V	108	Missense	distal	-3	no	38.311	39.974	EPSD	COSMIC	38.013	Up-regulation
CMGC_MAPK_p38_MAPK13_ST	P10636	MAPT	O15264	MAPK13	T111	G107R	107	Missense	distal	-4	no	38.311	41.240	EPSD	COSMIC	38.013	Up-regulation
CMGC_MAPK_p38_MAPK13_ST	P10636	MAPT	O15264	MAPK13	S171	G172V	172	Missense	proximal	1	no	-32.244	42.743	EPSD	COSMIC	38.013	Gain
CMGC_MAPK_p38_MAPK13_ST	P10636	MAPT	O15264	MAPK13	S228	S227N	227	Missense	proximal	-1	no	46.272	45.843	EPSD	COSMIC	38.013	Down-regulation
CMGC_MAPK_p38_MAPK13_ST	P10636	MAPT	O15264	MAPK13	S228	S227I	227	Missense	proximal	-1	no	46.272	45.469	EPSD	COSMIC	38.013	Down-regulation
CMGC_MAPK_p38_MAPK13_ST	P10636	MAPT	O15264	MAPK13	S228	E226K	226	Missense	proximal	-2	no	46.272	47.557	EPSD	COSMIC	38.013	Up-regulation
CMGC_MAPK_p38_MAPK13_ST	P10636	MAPT	O15264	MAPK13	S228	Q230R	230	Missense	proximal	2	no	46.272	47.861	EPSD	COSMIC	38.013	Up-regulation
CMGC_MAPK_p38_MAPK13_ST	P10636	MAPT	O15264	MAPK13	S228	P233S	233	Missense	distal	5	no	46.272	46.666	EPSD	COSMIC	38.013	Up-regulation
CMGC_MAPK_p38_MAPK13_ST	P10636	MAPT	O15264	MAPK13	S228	D225E	225	Missense	distal	-3	no	46.272	45.860	EPSD	COSMIC	38.013	Down-regulation
CMGC_MAPK_p38_MAPK13_ST	P10636	MAPT	O15264	MAPK13	S228	S227G	227	Missense	proximal	-1	no	46.272	45.829	EPSD	COSMIC	38.013	Down-regulation
CMGC_MAPK_p38_MAPK13_ST	P10636	MAPT	O15264	MAPK13	S228	S235L	235	Missense	distal	7	no	46.272	45.209	EPSD	COSMIC	38.013	Down-regulation
CMGC_MAPK_p38_MAPK13_ST	P10636	MAPT	O15264	MAPK13	S232	S227N	227	Missense	distal	-5	no	50.046	50.256	EPSD	COSMIC	38.013	Up-regulation
CMGC_MAPK_p38_MAPK13_ST	P10636	MAPT	O15264	MAPK13	S232	S227I	227	Missense	distal	-5	no	50.046	50.935	EPSD	COSMIC	38.013	Up-regulation
CMGC_MAPK_p38_MAPK13_ST	P10636	MAPT	O15264	MAPK13	S232	A237T	237	Missense	distal	5	no	50.046	50.468	EPSD	COSMIC	38.013	Up-regulation
CMGC_MAPK_p38_MAPK13_ST	P10636	MAPT	O15264	MAPK13	S232	E226K	226	Missense	distal	-6	no	50.046	50.910	EPSD	COSMIC	38.013	Up-regulation
CMGC_MAPK_p38_MAPK13_ST	P10636	MAPT	O15264	MAPK13	S232	Q230R	230	Missense	proximal	-2	no	50.046	49.984	EPSD	COSMIC	38.013	Down-regulation
CMGC_MAPK_p38_MAPK13_ST	P10636	MAPT	O15264	MAPK13	S232	S238P	238	Missense	distal	6	no	50.046	49.982	EPSD	COSMIC	38.013	Down-regulation
CMGC_MAPK_p38_MAPK13_ST	P10636	MAPT	O15264	MAPK13	S232	P233S	233	Missense	proximal	1	no	50.046	24.494	EPSD	COSMIC	38.013	Loss
CMGC_MAPK_p38_MAPK13_ST	P10636	MAPT	O15264	MAPK13	S232	S238F	238	Missense	distal	6	no	50.046	49.541	EPSD	COSMIC	38.013	Down-regulation
CMGC_MAPK_p38_MAPK13_ST	P10636	MAPT	O15264	MAPK13	S232	D225E	225	Missense	distal	-7	no	50.046	50.506	EPSD	COSMIC	38.013	Up-regulation
CMGC_MAPK_p38_MAPK13_ST	P10636	MAPT	O15264	MAPK13	S232	S227G	227	Missense	distal	-5	no	50.046	50.492	EPSD	COSMIC	38.013	Up-regulation
CMGC_MAPK_p38_MAPK13_ST	P10636	MAPT	O15264	MAPK13	S232	S235L	235	Missense	distal	3	no	50.046	49.591	EPSD	COSMIC	38.013	Down-regulation
CMGC_MAPK_p38_MAPK13_ST	P10636	MAPT	O15264	MAPK13	S238	A237T	237	Missense	proximal	-1	no	52.512	53.346	EPSD	COSMIC	38.013	Up-regulation
CMGC_MAPK_p38_MAPK13_ST	P10636	MAPT	O15264	MAPK13	S238	A240S	240	Missense	proximal	2	no	52.512	54.416	EPSD	COSMIC	38.013	Up-regulation
CMGC_MAPK_p38_MAPK13_ST	P10636	MAPT	O15264	MAPK13	S238	D242N	242	Missense	distal	4	no	52.512	52.411	EPSD	COSMIC	38.013	Down-regulation
CMGC_MAPK_p38_MAPK13_ST	P10636	MAPT	O15264	MAPK13	S238	R244W	244	Missense	distal	6	no	52.512	51.912	EPSD	COSMIC	38.013	Down-regulation
CMGC_MAPK_p38_MAPK13_ST	P10636	MAPT	O15264	MAPK13	S238	S238P	238	Missense	central	0	yes	52.512	0.000	EPSD	COSMIC	38.013	Loss
CMGC_MAPK_p38_MAPK13_ST	P10636	MAPT	O15264	MAPK13	S238	P233S	233	Missense	distal	-5	no	52.512	52.202	EPSD	COSMIC	38.013	Down-regulation
CMGC_MAPK_p38_MAPK13_ST	P10636	MAPT	O15264	MAPK13	S238	S238F	238	Missense	central	0	yes	52.512	0.000	EPSD	COSMIC	38.013	Loss
CMGC_MAPK_p38_MAPK13_ST	P10636	MAPT	O15264	MAPK13	S238	G243D	243	Missense	distal	5	no	52.512	52.578	EPSD	COSMIC	38.013	Up-regulation
CMGC_MAPK_p38_MAPK13_ST	P10636	MAPT	O15264	MAPK13	S238	S235L	235	Missense	distal	-3	no	52.512	51.516	EPSD	COSMIC	38.013	Down-regulation
CMGC_MAPK_p38_MAPK13_ST	P10636	MAPT	O15264	MAPK13	S388	D389N	389	Missense	proximal	1	no	32.769	53.193	EPSD	COSMIC;GDSC;CCLE	38.013	Gain
CMGC_MAPK_p38_MAPK13_ST	P10636	MAPT	O15264	MAPK13	S396	R398C	398	Missense	proximal	2	no	42.736	38.734	EPSD;PhosphoSitePlus	COSMIC	38.013	Down-regulation
CMGC_MAPK_p38_MAPK13_ST	P10636	MAPT	O15264	MAPK13	S396	S396F	396	Missense	central	0	yes	42.736	0.000	EPSD;PhosphoSitePlus	COSMIC	38.013	Loss
CMGC_MAPK_p38_MAPK13_ST	P10636	MAPT	O15264	MAPK13	S396	D389N	389	Missense	distal	-7	no	42.736	43.327	EPSD;PhosphoSitePlus	COSMIC;GDSC;CCLE	38.013	Up-regulation
CMGC_MAPK_p38_MAPK13_ST	P10636	MAPT	O15264	MAPK13	T403	L410F	410	Missense	distal	7	no	39.010	38.675	EPSD	COSMIC	38.013	Down-regulation
CMGC_MAPK_p38_MAPK13_ST	P10636	MAPT	O15264	MAPK13	T403	R398C	398	Missense	distal	-5	no	39.010	40.024	EPSD	COSMIC	38.013	Up-regulation
CMGC_MAPK_p38_MAPK13_ST	P10636	MAPT	O15264	MAPK13	T403	S396F	396	Missense	distal	-7	no	39.010	37.053	EPSD	COSMIC	38.013	Loss
CMGC_MAPK_p38_MAPK13_ST	P10636	MAPT	O15264	MAPK13	S411	L410F	410	Missense	proximal	-1	no	52.055	52.003	EPSD	COSMIC	38.013	Down-regulation
CMGC_MAPK_p38_MAPK13_ST	P10636	MAPT	O15264	MAPK13	S411	P412S	412	Missense	proximal	1	no	52.055	26.504	EPSD	COSMIC	38.013	Loss
CMGC_MAPK_p38_MAPK13_ST	P10636	MAPT	O15264	MAPK13	T416	L410F	410	Missense	distal	-6	no	50.749	50.596	EPSD	COSMIC	38.013	Down-regulation
CMGC_MAPK_p38_MAPK13_ST	P10636	MAPT	O15264	MAPK13	T416	P412S	412	Missense	distal	-4	no	50.749	51.758	EPSD	COSMIC	38.013	Up-regulation
CMGC_MAPK_p38_MAPK13_ST	P10636	MAPT	O15264	MAPK13	S438	S443Y	443	Missense	distal	5	no	49.548	49.088	EPSD	COSMIC	38.013	Down-regulation
CMGC_MAPK_p38_MAPK13_ST	P10636	MAPT	O15264	MAPK13	S447	S443Y	443	Missense	distal	-4	no	43.110	40.966	EPSD	COSMIC	38.013	Down-regulation
CMGC_MAPK_p38_MAPK13_ST	P10636	MAPT	O15264	MAPK13	S447	S447P	447	Missense	central	0	yes	43.110	0.000	EPSD	COSMIC	38.013	Loss
CMGC_MAPK_p38_MAPK13_ST	P10636	MAPT	O15264	MAPK13	S447	R448Q	448	Missense	proximal	1	no	43.110	46.495	EPSD	COSMIC	38.013	Up-regulation
CMGC_MAPK_p38_MAPK13_ST	P10636	MAPT	O15264	MAPK13	T470	T466M	466	Missense	distal	-4	no	55.325	53.316	EPSD	COSMIC;GDSC;CCLE	38.013	Down-regulation
CMGC_MAPK_p38_MAPK13_ST	P10636	MAPT	O15264	MAPK13	T470	K467T	467	Missense	distal	-3	no	55.325	55.707	EPSD	COSMIC	38.013	Up-regulation
CMGC_MAPK_p38_MAPK13_ST	P10636	MAPT	O15264	MAPK13	T470	P477L	477	Missense	distal	7	no	55.325	54.306	EPSD	COSMIC	38.013	Down-regulation
CMGC_MAPK_p38_MAPK13_ST	P10636	MAPT	O15264	MAPK13	T470	P477S	477	Missense	distal	7	no	55.325	55.369	EPSD	COSMIC	38.013	Up-regulation
CMGC_MAPK_p38_MAPK13_ST	P10636	MAPT	O15264	MAPK13	T486	R487K	487	Missense	proximal	1	no	40.318	30.138	EPSD	COSMIC	38.013	Loss
CMGC_MAPK_p38_MAPK13_ST	P10636	MAPT	O15264	MAPK13	T486	K491R	491	Missense	distal	5	no	40.318	40.635	EPSD	COSMIC	38.013	Up-regulation
CMGC_MAPK_p38_MAPK13_ST	P10636	MAPT	O15264	MAPK13	T486	R487G	487	Missense	proximal	1	no	40.318	-30.892	EPSD	COSMIC	38.013	Loss
CMGC_MAPK_p38_MAPK13_ST	P10636	MAPT	O15264	MAPK13	T486	P493L	493	Missense	distal	7	no	40.318	39.300	EPSD	COSMIC	38.013	Down-regulation
CMGC_MAPK_p38_MAPK13_ST	P10636	MAPT	O15264	MAPK13	T492	R487K	487	Missense	distal	-5	no	46.786	47.018	EPSD	COSMIC	38.013	Up-regulation
CMGC_MAPK_p38_MAPK13_ST	P10636	MAPT	O15264	MAPK13	T492	K491R	491	Missense	proximal	-1	no	46.786	47.060	EPSD	COSMIC	38.013	Up-regulation
CMGC_MAPK_p38_MAPK13_ST	P10636	MAPT	O15264	MAPK13	T492	R487G	487	Missense	distal	-5	no	46.786	47.207	EPSD	COSMIC	38.013	Up-regulation
CMGC_MAPK_p38_MAPK13_ST	P10636	MAPT	O15264	MAPK13	T492	A495T	495	Missense	distal	3	no	46.786	47.093	EPSD	COSMIC	38.013	Up-regulation
CMGC_MAPK_p38_MAPK13_ST	P10636	MAPT	O15264	MAPK13	T492	P493L	493	Missense	proximal	1	no	46.786	34.354	EPSD	COSMIC	38.013	Loss
CMGC_MAPK_p38_MAPK13_ST	P10636	MAPT	O15264	MAPK13	T498	K491R	491	Missense	distal	-7	no	42.899	44.288	EPSD	COSMIC	38.013	Up-regulation
CMGC_MAPK_p38_MAPK13_ST	P10636	MAPT	O15264	MAPK13	T498	A495T	495	Missense	distal	-3	no	42.899	44.191	EPSD	COSMIC	38.013	Up-regulation
CMGC_MAPK_p38_MAPK13_ST	P10636	MAPT	O15264	MAPK13	T498	P493L	493	Missense	distal	-5	no	42.899	43.186	EPSD	COSMIC	38.013	Up-regulation
CMGC_MAPK_p38_MAPK13_ST	P10636	MAPT	O15264	MAPK13	S508	G509V	509	Missense	proximal	1	no	-29.721	45.266	EPSD	COSMIC	38.013	Gain
CMGC_MAPK_p38_MAPK13_ST	P10636	MAPT	O15264	MAPK13	S516	G521V	521	Missense	distal	5	no	57.896	58.083	EPSD	COSMIC	38.013	Up-regulation
CMGC_MAPK_p38_MAPK13_ST	P10636	MAPT	O15264	MAPK13	S516	G518V	518	Missense	proximal	2	no	57.896	59.309	EPSD	COSMIC	38.013	Up-regulation
CMGC_MAPK_p38_MAPK13_ST	P10636	MAPT	O15264	MAPK13	S516	R511C	511	Missense	distal	-5	no	57.896	58.910	EPSD	COSMIC;CCLE	38.013	Up-regulation
CMGC_MAPK_p38_MAPK13_ST	P10636	MAPT	O15264	MAPK13	S516	G509V	509	Missense	distal	-7	no	57.896	56.505	EPSD	COSMIC	38.013	Down-regulation
CMGC_MAPK_p38_MAPK13_ST	P10636	MAPT	O15264	MAPK13	S519	G521V	521	Missense	proximal	2	no	62.266	63.678	EPSD	COSMIC	38.013	Up-regulation
CMGC_MAPK_p38_MAPK13_ST	P10636	MAPT	O15264	MAPK13	S519	R526H	526	Missense	distal	7	no	62.266	61.817	EPSD	COSMIC	38.013	Down-regulation
CMGC_MAPK_p38_MAPK13_ST	P10636	MAPT	O15264	MAPK13	S519	G518V	518	Missense	proximal	-1	no	62.266	62.400	EPSD	COSMIC	38.013	Up-regulation
CMGC_MAPK_p38_MAPK13_ST	P10636	MAPT	O15264	MAPK13	T522	G521V	521	Missense	proximal	-1	no	58.788	58.922	EPSD	COSMIC	38.013	Up-regulation
CMGC_MAPK_p38_MAPK13_ST	P10636	MAPT	O15264	MAPK13	T522	R526H	526	Missense	distal	4	no	58.788	58.977	EPSD	COSMIC	38.013	Up-regulation
CMGC_MAPK_p38_MAPK13_ST	P10636	MAPT	O15264	MAPK13	T522	G518V	518	Missense	distal	-4	no	58.788	59.972	EPSD	COSMIC	38.013	Up-regulation
CMGC_MAPK_p38_MAPK13_ST	P10636	MAPT	O15264	MAPK13	T522	R528S	528	Missense	distal	6	no	58.788	58.854	EPSD	COSMIC	38.013	Up-regulation
CMGC_MAPK_p38_MAPK13_ST	P10636	MAPT	O15264	MAPK13	S525	G521V	521	Missense	distal	-4	no	42.544	43.728	EPSD	COSMIC	38.013	Up-regulation
CMGC_MAPK_p38_MAPK13_ST	P10636	MAPT	O15264	MAPK13	S525	R526H	526	Missense	proximal	1	no	42.544	26.207	EPSD	COSMIC	38.013	Loss
CMGC_MAPK_p38_MAPK13_ST	P10636	MAPT	O15264	MAPK13	S525	G518V	518	Missense	distal	-7	no	42.544	41.153	EPSD	COSMIC	38.013	Down-regulation
CMGC_MAPK_p38_MAPK13_ST	P10636	MAPT	O15264	MAPK13	S525	R528S	528	Missense	distal	3	no	42.544	42.565	EPSD	COSMIC	38.013	Up-regulation
CMGC_MAPK_p38_MAPK13_ST	P10636	MAPT	O15264	MAPK13	S525	P530S	530	Missense	distal	5	no	42.544	42.938	EPSD	COSMIC	38.013	Up-regulation
CMGC_MAPK_p38_MAPK13_ST	P10636	MAPT	O15264	MAPK13	S527	G521V	521	Missense	distal	-6	no	43.486	43.790	EPSD	COSMIC	38.013	Up-regulation
CMGC_MAPK_p38_MAPK13_ST	P10636	MAPT	O15264	MAPK13	S527	R526H	526	Missense	proximal	-1	no	43.486	42.812	EPSD	COSMIC	38.013	Down-regulation
CMGC_MAPK_p38_MAPK13_ST	P10636	MAPT	O15264	MAPK13	S527	R528S	528	Missense	proximal	1	no	43.486	29.982	EPSD	COSMIC	38.013	Loss
CMGC_MAPK_p38_MAPK13_ST	P10636	MAPT	O15264	MAPK13	S527	P530S	530	Missense	distal	3	no	43.486	43.741	EPSD	COSMIC	38.013	Up-regulation
CMGC_MAPK_p38_MAPK13_ST	P10636	MAPT	O15264	MAPK13	T529	R526H	526	Missense	distal	-3	no	61.630	61.155	EPSD	COSMIC	38.013	Down-regulation
CMGC_MAPK_p38_MAPK13_ST	P10636	MAPT	O15264	MAPK13	T529	R528S	528	Missense	proximal	-1	no	61.630	61.593	EPSD	COSMIC	38.013	Down-regulation
CMGC_MAPK_p38_MAPK13_ST	P10636	MAPT	O15264	MAPK13	T529	P530S	530	Missense	proximal	1	no	61.630	36.079	EPSD	COSMIC	38.013	Loss
CMGC_MAPK_p38_MAPK13_ST	P10636	MAPT	O15264	MAPK13	T529	P536H	536	Missense	distal	7	no	61.630	61.048	EPSD	COSMIC	38.013	Down-regulation
CMGC_MAPK_p38_MAPK13_ST	P10636	MAPT	O15264	MAPK13	T529	P535Q	535	Missense	distal	6	no	61.630	61.434	EPSD	COSMIC	38.013	Down-regulation
CMGC_MAPK_p38_MAPK13_ST	P10636	MAPT	O15264	MAPK13	S531	R526H	526	Missense	distal	-5	no	47.793	48.257	EPSD	COSMIC	38.013	Up-regulation
CMGC_MAPK_p38_MAPK13_ST	P10636	MAPT	O15264	MAPK13	S531	R528S	528	Missense	distal	-3	no	47.793	47.879	EPSD	COSMIC	38.013	Up-regulation
CMGC_MAPK_p38_MAPK13_ST	P10636	MAPT	O15264	MAPK13	S531	P530S	530	Missense	proximal	-1	no	47.793	47.914	EPSD	COSMIC	38.013	Up-regulation
CMGC_MAPK_p38_MAPK13_ST	P10636	MAPT	O15264	MAPK13	S531	P536H	536	Missense	distal	5	no	47.793	47.810	EPSD	COSMIC	38.013	Up-regulation
CMGC_MAPK_p38_MAPK13_ST	P10636	MAPT	O15264	MAPK13	S531	P535Q	535	Missense	distal	4	no	47.793	47.233	EPSD	COSMIC	38.013	Down-regulation
CMGC_MAPK_p38_MAPK13_ST	P10636	MAPT	O15264	MAPK13	T534	R528S	528	Missense	distal	-6	no	57.091	56.984	EPSD	COSMIC	38.013	Down-regulation
CMGC_MAPK_p38_MAPK13_ST	P10636	MAPT	O15264	MAPK13	T534	P530S	530	Missense	distal	-4	no	57.091	58.101	EPSD	COSMIC	38.013	Up-regulation
CMGC_MAPK_p38_MAPK13_ST	P10636	MAPT	O15264	MAPK13	T534	P536H	536	Missense	proximal	2	no	57.091	56.720	EPSD	COSMIC	38.013	Down-regulation
CMGC_MAPK_p38_MAPK13_ST	P10636	MAPT	O15264	MAPK13	T534	P535Q	535	Missense	proximal	1	no	57.091	48.428	EPSD	COSMIC	38.013	Down-regulation
CMGC_MAPK_p38_MAPK13_ST	P10636	MAPT	O15264	MAPK13	T534	E539Q	539	Missense	distal	5	no	57.091	57.408	EPSD	COSMIC	38.013	Up-regulation
CMGC_MAPK_p38_MAPK13_ST	P10636	MAPT	O15264	MAPK13	T537	P530S	530	Missense	distal	-7	no	52.019	53.439	EPSD	COSMIC	38.013	Up-regulation
CMGC_MAPK_p38_MAPK13_ST	P10636	MAPT	O15264	MAPK13	T537	P536H	536	Missense	proximal	-1	no	52.019	51.503	EPSD	COSMIC	38.013	Down-regulation
CMGC_MAPK_p38_MAPK13_ST	P10636	MAPT	O15264	MAPK13	T537	P535Q	535	Missense	proximal	-2	no	52.019	51.572	EPSD	COSMIC	38.013	Down-regulation
CMGC_MAPK_p38_MAPK13_ST	P10636	MAPT	O15264	MAPK13	T537	E539Q	539	Missense	proximal	2	no	52.019	53.027	EPSD	COSMIC	38.013	Up-regulation
CMGC_MAPK_p38_MAPK13_ST	P10636	MAPT	O15264	MAPK13	T548	P550S	550	Missense	proximal	2	no	58.559	59.002	EPSD	COSMIC	38.013	Up-regulation
CMGC_MAPK_p38_MAPK13_ST	P10636	MAPT	O15264	MAPK13	T548	P553R	553	Missense	distal	5	no	58.559	59.090	EPSD	COSMIC	38.013	Up-regulation
CMGC_MAPK_p38_MAPK13_ST	P10636	MAPT	O15264	MAPK13	T548	P553L	553	Missense	distal	5	no	58.559	58.479	EPSD	COSMIC	38.013	Down-regulation
CMGC_MAPK_p38_MAPK13_ST	P10636	MAPT	O15264	MAPK13	T548	P549L	549	Missense	proximal	1	no	58.559	46.127	EPSD	COSMIC	38.013	Down-regulation
CMGC_MAPK_p38_MAPK13_ST	P10636	MAPT	O15264	MAPK13	T548	S555F	555	Missense	distal	7	no	58.559	57.161	EPSD	COSMIC	38.013	Down-regulation
CMGC_MAPK_p38_MAPK13_ST	P10636	MAPT	O15264	MAPK13	T548	P553Q	553	Missense	distal	5	no	58.559	58.822	EPSD	COSMIC	38.013	Up-regulation
CMGC_MAPK_p38_MAPK13_ST	P10636	MAPT	O15264	MAPK13	S552	P550S	550	Missense	proximal	-2	no	60.759	60.053	EPSD	COSMIC	38.013	Down-regulation
CMGC_MAPK_p38_MAPK13_ST	P10636	MAPT	O15264	MAPK13	S552	R559C	559	Missense	distal	7	no	60.759	59.244	EPSD	COSMIC	38.013	Down-regulation
CMGC_MAPK_p38_MAPK13_ST	P10636	MAPT	O15264	MAPK13	S552	P553R	553	Missense	proximal	1	no	60.759	48.711	EPSD	COSMIC	38.013	Down-regulation
CMGC_MAPK_p38_MAPK13_ST	P10636	MAPT	O15264	MAPK13	S552	P553L	553	Missense	proximal	1	no	60.759	48.326	EPSD	COSMIC	38.013	Down-regulation
CMGC_MAPK_p38_MAPK13_ST	P10636	MAPT	O15264	MAPK13	S552	P549L	549	Missense	distal	-3	no	60.759	59.723	EPSD	COSMIC	38.013	Down-regulation
CMGC_MAPK_p38_MAPK13_ST	P10636	MAPT	O15264	MAPK13	S552	S555F	555	Missense	distal	3	no	60.759	60.285	EPSD	COSMIC	38.013	Down-regulation
CMGC_MAPK_p38_MAPK13_ST	P10636	MAPT	O15264	MAPK13	S552	P553Q	553	Missense	proximal	1	no	60.759	52.096	EPSD	COSMIC	38.013	Down-regulation
CMGC_MAPK_p38_MAPK13_ST	P10636	MAPT	O15264	MAPK13	S558	V565M	565	Missense	distal	7	no	40.639	40.011	EPSD	COSMIC	38.013	Down-regulation
CMGC_MAPK_p38_MAPK13_ST	P10636	MAPT	O15264	MAPK13	S558	R559C	559	Missense	proximal	1	no	40.639	1.957	EPSD	COSMIC	38.013	Loss
CMGC_MAPK_p38_MAPK13_ST	P10636	MAPT	O15264	MAPK13	S558	P553R	553	Missense	distal	-5	no	40.639	40.355	EPSD	COSMIC	38.013	Down-regulation
CMGC_MAPK_p38_MAPK13_ST	P10636	MAPT	O15264	MAPK13	S558	P553L	553	Missense	distal	-5	no	40.639	40.926	EPSD	COSMIC	38.013	Up-regulation
CMGC_MAPK_p38_MAPK13_ST	P10636	MAPT	O15264	MAPK13	S558	S555F	555	Missense	distal	-3	no	40.639	39.401	EPSD	COSMIC	38.013	Down-regulation
CMGC_MAPK_p38_MAPK13_ST	P10636	MAPT	O15264	MAPK13	S558	P553Q	553	Missense	distal	-5	no	40.639	40.426	EPSD	COSMIC	38.013	Down-regulation
CMGC_MAPK_p38_MAPK13_ST	P10636	MAPT	O15264	MAPK13	S579	T580N	580	Missense	proximal	1	no	25.100	39.389	EPSD	COSMIC	38.013	Gain
CMGC_MAPK_p38_MAPK13_ST	P10636	MAPT	O15264	MAPK13	S602	I595L	595	Missense	distal	-7	no	37.680	38.627	EPSD	COSMIC	38.013	Gain
CMGC_MAPK_p38_MAPK13_ST	P10636	MAPT	O15264	MAPK13	S713	E708D	708	Missense	distal	-5	no	51.455	51.017	EPSD	COSMIC	38.013	Down-regulation
CMGC_MAPK_p38_MAPK13_ST	P10636	MAPT	O15264	MAPK13	S713	G706R	706	Missense	distal	-7	no	51.455	51.942	EPSD	COSMIC	38.013	Up-regulation
CMGC_MAPK_p38_MAPK13_ST	P10636	MAPT	O15264	MAPK13	S713	V710M	710	Missense	distal	-3	no	51.455	50.302	EPSD	COSMIC	38.013	Down-regulation
CMGC_MAPK_p38_MAPK13_ST	P10636	MAPT	O15264	MAPK13	S713	E708K	708	Missense	distal	-5	no	51.455	51.072	EPSD	COSMIC	38.013	Down-regulation
CMGC_MAPK_p38_MAPK13_ST	P10636	MAPT	O15264	MAPK13	S713	V710A	710	Missense	distal	-3	no	51.455	50.415	EPSD	COSMIC	38.013	Down-regulation
CMGC_MAPK_p38_MAPK13_ST	P10636	MAPT	O15264	MAPK13	S721	R723W	723	Missense	proximal	2	no	55.304	51.436	EPSD	COSMIC	38.013	Down-regulation
CMGC_MAPK_p38_MAPK13_ST	P10636	MAPT	O15264	MAPK13	S721	V728M	728	Missense	distal	7	no	55.304	54.675	EPSD	COSMIC	38.013	Down-regulation
CMGC_MAPK_p38_MAPK13_ST	P10636	MAPT	O15264	MAPK13	S721	V728A	728	Missense	distal	7	no	55.304	54.770	EPSD	COSMIC	38.013	Down-regulation
CMGC_MAPK_p38_MAPK13_ST	P10636	MAPT	O15264	MAPK13	S726	G732S	732	Missense	distal	6	no	38.862	39.422	EPSD	COSMIC	38.013	Up-regulation
CMGC_MAPK_p38_MAPK13_ST	P10636	MAPT	O15264	MAPK13	S726	G732C	732	Missense	distal	6	no	38.862	38.653	EPSD	COSMIC	38.013	Down-regulation
CMGC_MAPK_p38_MAPK13_ST	P10636	MAPT	O15264	MAPK13	S726	R723W	723	Missense	distal	-3	no	38.862	37.228	EPSD	COSMIC	38.013	Loss
CMGC_MAPK_p38_MAPK13_ST	P10636	MAPT	O15264	MAPK13	S726	V728M	728	Missense	proximal	2	no	38.862	36.712	EPSD	COSMIC	38.013	Loss
CMGC_MAPK_p38_MAPK13_ST	P10636	MAPT	O15264	MAPK13	S726	V728A	728	Missense	proximal	2	no	38.862	36.592	EPSD	COSMIC	38.013	Loss
CMGC_MAPK_p38_MAPK13_ST	P10636	MAPT	O15264	MAPK13	S739	G732S	732	Missense	distal	-7	no	54.284	53.626	EPSD	COSMIC	38.013	Down-regulation
CMGC_MAPK_p38_MAPK13_ST	P10636	MAPT	O15264	MAPK13	S739	D735N	735	Missense	distal	-4	no	54.284	53.810	EPSD	COSMIC	38.013	Down-regulation
CMGC_MAPK_p38_MAPK13_ST	P10636	MAPT	O15264	MAPK13	S739	G732C	732	Missense	distal	-7	no	54.284	50.887	EPSD	COSMIC	38.013	Down-regulation
CMGC_MAPK_p38_MAPK13_ST	P10636	MAPT	O15264	MAPK13	S739	T744M	744	Missense	distal	5	no	54.284	53.963	EPSD	COSMIC	38.013	Down-regulation
CMGC_MAPK_p38_MAPK13_ST	P10636	MAPT	O15264	MAPK13	S739	A743T	743	Missense	distal	4	no	54.284	54.719	EPSD	COSMIC	38.013	Up-regulation
CMGC_MAPK_p38_MAPK13_ST	Q00613	HSF1	O15264	MAPK13	S121	T120A	120	Missense	proximal	-1	no	43.545	42.710	EPSD	COSMIC	38.013	Down-regulation
CMGC_MAPK_p38_MAPK13_ST	Q00613	HSF1	O15264	MAPK13	T124	D129G	129	Missense	distal	5	no	40.741	40.674	EPSD	COSMIC	38.013	Down-regulation
CMGC_MAPK_p38_MAPK13_ST	Q00613	HSF1	O15264	MAPK13	T124	T120A	120	Missense	distal	-4	no	40.741	39.620	EPSD	COSMIC	38.013	Down-regulation
CMGC_MAPK_p38_MAPK13_ST	Q00613	HSF1	O15264	MAPK13	S230	R227Q	227	Missense	distal	-3	no	43.527	43.418	EPSD	COSMIC;GDSC	38.013	Down-regulation
CMGC_MAPK_p38_MAPK13_ST	Q00613	HSF1	O15264	MAPK13	S230	G236S	236	Missense	distal	6	no	43.527	44.087	EPSD	COSMIC;CCLE	38.013	Up-regulation
CMGC_MAPK_p38_MAPK13_ST	Q00613	HSF1	O15264	MAPK13	S230	S237L	237	Missense	distal	7	no	43.527	42.464	EPSD	COSMIC	38.013	Down-regulation
CMGC_MAPK_p38_MAPK13_ST	Q00613	HSF1	O15264	MAPK13	S244	S237L	237	Missense	distal	-7	no	43.089	41.831	EPSD	COSMIC	38.013	Down-regulation
CMGC_MAPK_p38_MAPK13_ST	Q00613	HSF1	O15264	MAPK13	S244	P239H	239	Missense	distal	-5	no	43.089	43.269	EPSD	COSMIC	38.013	Up-regulation
CMGC_MAPK_p38_MAPK13_ST	Q00613	HSF1	O15264	MAPK13	S244	S244F	244	Missense	central	0	yes	43.089	0.000	EPSD	COSMIC	38.013	Loss
CMGC_MAPK_p38_MAPK13_ST	Q00613	HSF1	O15264	MAPK13	S275	S279F	279	Missense	distal	4	no	42.780	41.603	EPSD	COSMIC	38.013	Down-regulation
CMGC_MAPK_p38_MAPK13_ST	Q00613	HSF1	O15264	MAPK13	S275	P280L	280	Missense	distal	5	no	42.780	42.699	EPSD	COSMIC	38.013	Down-regulation
CMGC_MAPK_p38_MAPK13_ST	Q00613	HSF1	O15264	MAPK13	S275	I268V	268	Missense	distal	-7	no	42.780	44.251	EPSD	COSMIC	38.013	Up-regulation
CMGC_MAPK_p38_MAPK13_ST	Q00613	HSF1	O15264	MAPK13	S275	G281S	281	Missense	distal	6	no	42.780	43.340	EPSD	COSMIC	38.013	Up-regulation
CMGC_MAPK_p38_MAPK13_ST	Q00613	HSF1	O15264	MAPK13	S279	S279F	279	Missense	central	0	yes	43.061	0.000	EPSD	COSMIC	38.013	Loss
CMGC_MAPK_p38_MAPK13_ST	Q00613	HSF1	O15264	MAPK13	S279	P280L	280	Missense	proximal	1	no	43.061	30.629	EPSD	COSMIC	38.013	Loss
CMGC_MAPK_p38_MAPK13_ST	Q00613	HSF1	O15264	MAPK13	S279	G281S	281	Missense	proximal	2	no	43.061	44.108	EPSD	COSMIC	38.013	Up-regulation
CMGC_MAPK_p38_MAPK13_ST	Q00613	HSF1	O15264	MAPK13	S279	S283N	283	Missense	distal	4	no	43.061	42.558	EPSD	COSMIC	38.013	Down-regulation
CMGC_MAPK_p38_MAPK13_ST	Q00613	HSF1	O15264	MAPK13	S292	R287K	287	Missense	distal	-5	no	41.730	41.962	EPSD	COSMIC	38.013	Up-regulation
CMGC_MAPK_p38_MAPK13_ST	Q00613	HSF1	O15264	MAPK13	S303	S303G	303	Missense	central	0	yes	55.917	0.000	EPSD;PhosphoSitePlus	COSMIC	38.013	Loss
CMGC_MAPK_p38_MAPK13_ST	Q00613	HSF1	O15264	MAPK13	S303	P304L	304	Missense	proximal	1	no	55.917	43.485	EPSD;PhosphoSitePlus	COSMIC;GDSC	38.013	Down-regulation
CMGC_MAPK_p38_MAPK13_ST	Q00613	HSF1	O15264	MAPK13	S303	R309G	309	Missense	distal	6	no	55.917	55.424	EPSD;PhosphoSitePlus	COSMIC	38.013	Down-regulation
CMGC_MAPK_p38_MAPK13_ST	Q00613	HSF1	O15264	MAPK13	S307	S303G	303	Missense	distal	-4	no	58.266	55.720	PhosphoSitePlus;EPSD	COSMIC	38.013	Down-regulation
CMGC_MAPK_p38_MAPK13_ST	Q00613	HSF1	O15264	MAPK13	S307	P304L	304	Missense	distal	-3	no	58.266	57.230	PhosphoSitePlus;EPSD	COSMIC;GDSC	38.013	Down-regulation
CMGC_MAPK_p38_MAPK13_ST	Q00613	HSF1	O15264	MAPK13	S307	R309G	309	Missense	proximal	2	no	58.266	55.804	PhosphoSitePlus;EPSD	COSMIC	38.013	Down-regulation
CMGC_MAPK_p38_MAPK13_ST	Q00613	HSF1	O15264	MAPK13	S314	R309G	309	Missense	distal	-5	no	48.129	48.550	EPSD	COSMIC	38.013	Up-regulation
CMGC_MAPK_p38_MAPK13_ST	Q00613	HSF1	O15264	MAPK13	S314	P318T	318	Missense	distal	4	no	48.129	47.970	EPSD	COSMIC	38.013	Down-regulation
CMGC_MAPK_p38_MAPK13_ST	Q00613	HSF1	O15264	MAPK13	S326	L330V	330	Missense	distal	4	no	56.945	57.614	EPSD;PhosphoSitePlus	COSMIC	38.013	Up-regulation
CMGC_MAPK_p38_MAPK13_ST	Q00613	HSF1	O15264	MAPK13	S326	P327Q	327	Missense	proximal	1	no	56.945	48.282	EPSD;PhosphoSitePlus	COSMIC	38.013	Down-regulation
CMGC_MAPK_p38_MAPK13_ST	Q00613	HSF1	O15264	MAPK13	S344	T349M	349	Missense	distal	5	no	44.833	44.513	EPSD	COSMIC	38.013	Down-regulation
CMGC_MAPK_p38_MAPK13_ST	Q00613	HSF1	O15264	MAPK13	S344	P342T	342	Missense	proximal	-2	no	44.833	44.570	EPSD	COSMIC	38.013	Down-regulation
CMGC_MAPK_p38_MAPK13_ST	Q00613	HSF1	O15264	MAPK13	S344	S344C	344	Missense	central	0	yes	44.833	0.000	EPSD	COSMIC	38.013	Loss
CMGC_MAPK_p38_MAPK13_ST	Q00613	HSF1	O15264	MAPK13	T355	D356N	356	Missense	proximal	1	no	19.624	40.048	EPSD	COSMIC	38.013	Gain
CMGC_MAPK_p38_MAPK13_ST	Q00613	HSF1	O15264	MAPK13	S363	S363P	363	Missense	central	0	yes	46.018	0.000	EPSD	COSMIC	38.013	Loss
CMGC_MAPK_p38_MAPK13_ST	Q00613	HSF1	O15264	MAPK13	S363	P365Q	365	Missense	proximal	2	no	46.018	46.285	EPSD	COSMIC	38.013	Up-regulation
CMGC_MAPK_p38_MAPK13_ST	Q00613	HSF1	O15264	MAPK13	S363	D356N	356	Missense	distal	-7	no	46.018	46.609	EPSD	COSMIC	38.013	Up-regulation
CMGC_MAPK_p38_MAPK13_ST	Q00613	HSF1	O15264	MAPK13	S363	P365T	365	Missense	proximal	2	no	46.018	47.905	EPSD	COSMIC	38.013	Up-regulation
CMGC_MAPK_p38_MAPK13_ST	Q00613	HSF1	O15264	MAPK13	S363	E358K	358	Missense	distal	-5	no	46.018	45.635	EPSD	COSMIC	38.013	Down-regulation
CMGC_MAPK_p38_MAPK13_ST	Q00613	HSF1	O15264	MAPK13	S363	P365L	365	Missense	proximal	2	no	46.018	45.391	EPSD	COSMIC	38.013	Down-regulation
CMGC_MAPK_p38_MAPK13_ST	Q00613	HSF1	O15264	MAPK13	T369	S363P	363	Missense	distal	-6	no	44.201	43.575	EPSD	COSMIC	38.013	Down-regulation
CMGC_MAPK_p38_MAPK13_ST	Q00613	HSF1	O15264	MAPK13	T369	P365Q	365	Missense	distal	-4	no	44.201	43.736	EPSD	COSMIC	38.013	Down-regulation
CMGC_MAPK_p38_MAPK13_ST	Q00613	HSF1	O15264	MAPK13	T369	P365T	365	Missense	distal	-4	no	44.201	45.294	EPSD	COSMIC	38.013	Up-regulation
CMGC_MAPK_p38_MAPK13_ST	Q00613	HSF1	O15264	MAPK13	T369	L374F	374	Missense	distal	5	no	44.201	44.097	EPSD	COSMIC	38.013	Down-regulation
CMGC_MAPK_p38_MAPK13_ST	Q00613	HSF1	O15264	MAPK13	T369	P365L	365	Missense	distal	-4	no	44.201	42.229	EPSD	COSMIC	38.013	Down-regulation
CMGC_MAPK_p38_MAPK13_ST	Q00613	HSF1	O15264	MAPK13	S419	L417Q	417	Missense	proximal	-2	no	52.329	53.412	EPSD	COSMIC	38.013	Up-regulation
CMGC_MAPK_p38_MAPK13_ST	Q00613	HSF1	O15264	MAPK13	S419	V422M	422	Missense	distal	3	no	52.329	52.270	EPSD	COSMIC	38.013	Down-regulation
CMGC_MAPK_p38_MAPK13_ST	Q00613	HSF1	O15264	MAPK13	S419	S419N	419	Missense	central	0	yes	52.329	0.000	EPSD	COSMIC	38.013	Loss
CMGC_MAPK_p38_MAPK13_ST	Q00613	HSF1	O15264	MAPK13	S444	E447K	447	Missense	distal	3	no	44.546	45.014	EPSD	COSMIC	38.013	Up-regulation
CMGC_MAPK_p38_MAPK13_ST	Q00613	HSF1	O15264	MAPK13	S458	P452H	452	Missense	distal	-6	no	41.379	41.561	EPSD	COSMIC	38.013	Up-regulation
CMGC_MAPK_p38_MAPK13_ST	P16949	STMN1	O15264	MAPK13	S25	Q18E	18	Missense	distal	-7	no	47.830	46.860	PhosphoSitePlus;EPSD	COSMIC	38.013	Down-regulation
CMGC_MAPK_p38_MAPK13_ST	P16949	STMN1	O15264	MAPK13	S31	P36L	36	Missense	distal	5	no	41.372	41.291	EPSD	COSMIC	38.013	Down-regulation
CMGC_MAPK_p38_MAPK13_ST	P16949	STMN1	O15264	MAPK13	S38	D44N	44	Missense	distal	6	no	52.410	52.422	EPSD;PhosphoSitePlus	COSMIC	38.013	Up-regulation
CMGC_MAPK_p38_MAPK13_ST	P16949	STMN1	O15264	MAPK13	S38	P36L	36	Missense	proximal	-2	no	52.410	50.881	EPSD;PhosphoSitePlus	COSMIC	38.013	Down-regulation
CMGC_MAPK_p38_MAPK13_ST	Q13501	SQSTM1	O15264	MAPK13	S28	R22W	22	Missense	distal	-6	no	41.178	39.779	EPSD	COSMIC	38.013	Down-regulation
CMGC_MAPK_p38_MAPK13_ST	Q13501	SQSTM1	O15264	MAPK13	S28	A33V	33	Missense	distal	5	no	41.178	41.503	EPSD	COSMIC	38.013	Up-regulation
CMGC_MAPK_p38_MAPK13_ST	Q13501	SQSTM1	O15264	MAPK13	S28	E34K	34	Missense	distal	6	no	41.178	41.465	EPSD	COSMIC	38.013	Up-regulation
CMGC_MAPK_p38_MAPK13_ST	Q13501	SQSTM1	O15264	MAPK13	S170	A167T	167	Missense	distal	-3	no	44.023	45.315	EPSD	COSMIC	38.013	Up-regulation
CMGC_MAPK_p38_MAPK13_ST	Q13501	SQSTM1	O15264	MAPK13	S249	L248I	248	Missense	proximal	-1	no	47.618	47.570	EPSD	COSMIC	38.013	Down-regulation
CMGC_MAPK_p38_MAPK13_ST	Q13501	SQSTM1	O15264	MAPK13	T269	E274D	274	Missense	distal	5	no	54.468	54.622	PhosphoSitePlus;EPSD	COSMIC	38.013	Up-regulation
CMGC_MAPK_p38_MAPK13_ST	Q13501	SQSTM1	O15264	MAPK13	S272	E274D	274	Missense	proximal	2	no	54.137	54.398	EPSD;PhosphoSitePlus	COSMIC	38.013	Up-regulation
CMGC_MAPK_p38_MAPK13_ST	Q13501	SQSTM1	O15264	MAPK13	S284	C289Y	289	Missense	distal	5	no	43.411	43.732	EPSD	COSMIC;GDSC;CCLE	38.013	Up-regulation
CMGC_MAPK_p38_MAPK13_ST	Q13501	SQSTM1	O15264	MAPK13	S306	Q310H	310	Missense	distal	4	no	41.052	41.293	EPSD	COSMIC	38.013	Up-regulation
CMGC_MAPK_p38_MAPK13_ST	Q13501	SQSTM1	O15264	MAPK13	T339	H340N	340	Missense	proximal	1	no	19.014	39.611	EPSD	COSMIC	38.013	Gain
CMGC_MAPK_p38_MAPK13_ST	Q13501	SQSTM1	O15264	MAPK13	S355	P359S	359	Missense	distal	4	no	40.187	40.267	EPSD	COSMIC	38.013	Up-regulation
CMGC_MAPK_p38_MAPK13_ST	Q13501	SQSTM1	O15264	MAPK13	S355	E362D	362	Missense	distal	7	no	40.187	40.610	EPSD	COSMIC	38.013	Up-regulation
CMGC_MAPK_p38_MAPK13_ST	Q13501	SQSTM1	O15264	MAPK13	S355	T350I	350	Missense	distal	-5	no	40.187	41.226	EPSD	COSMIC	38.013	Up-regulation
CMGC_MAPK_p38_MAPK13_ST	Q13501	SQSTM1	O15264	MAPK13	S355	E360K	360	Missense	distal	5	no	40.187	40.456	EPSD	COSMIC	38.013	Up-regulation
CMGC_MAPK_p38_MAPK13_ST	P30281	CCND3	O15264	MAPK13	S133	P134A	134	Missense	proximal	1	no	43.271	15.494	EPSD	COSMIC	38.013	Loss
CMGC_MAPK_p38_MAPK13_ST	P30281	CCND3	O15264	MAPK13	S133	A131V	131	Missense	proximal	-2	no	43.271	44.343	EPSD	COSMIC	38.013	Up-regulation
CMGC_MAPK_p38_MAPK13_ST	P30281	CCND3	O15264	MAPK13	S133	L137V	137	Missense	distal	4	no	43.271	43.939	EPSD	COSMIC	38.013	Up-regulation
CMGC_MAPK_p38_MAPK13_ST	P30281	CCND3	O15264	MAPK13	S133	S133L	133	Missense	central	0	yes	43.271	0.000	EPSD	COSMIC	38.013	Loss
CMGC_MAPK_p38_MAPK13_ST	P30281	CCND3	O15264	MAPK13	S259	E253D	253	Missense	distal	-6	no	43.189	43.210	EPSD	COSMIC	38.013	Up-regulation
CMGC_MAPK_p38_MAPK13_ST	P30281	CCND3	O15264	MAPK13	S259	R256K	256	Missense	distal	-3	no	43.189	43.207	EPSD	COSMIC	38.013	Up-regulation
CMGC_MAPK_p38_MAPK13_ST	P30281	CCND3	O15264	MAPK13	S264	K268E	268	Missense	distal	4	no	54.196	52.952	EPSD	COSMIC	38.013	Down-regulation
CMGC_MAPK_p38_MAPK13_ST	P30281	CCND3	O15264	MAPK13	S264	P267L	267	Missense	distal	3	no	54.196	53.996	EPSD	COSMIC	38.013	Down-regulation
CMGC_MAPK_p38_MAPK13_ST	P30281	CCND3	O15264	MAPK13	S275	K268E	268	Missense	distal	-7	no	39.702	39.516	EPSD	COSMIC	38.013	Down-regulation
CMGC_MAPK_p38_MAPK13_ST	P30281	CCND3	O15264	MAPK13	S275	G277W	277	Missense	proximal	2	no	39.702	38.296	EPSD	COSMIC	38.013	Down-regulation
CMGC_MAPK_p38_MAPK13_ST	P30281	CCND3	O15264	MAPK13	T283	P284S	284	Missense	proximal	1	no	47.606	22.055	PhosphoSitePlus	COSMIC;CCLE	38.013	Loss
CMGC_MAPK_p38_MAPK13_ST	P30281	CCND3	O15264	MAPK13	T283	P284L	284	Missense	proximal	1	no	47.606	35.174	PhosphoSitePlus	COSMIC;CCLE	38.013	Loss
CMGC_MAPK_p38_MAPK13_ST	P30281	CCND3	O15264	MAPK13	T283	I290R	290	Missense	distal	7	no	47.606	48.573	PhosphoSitePlus	COSMIC;CCLE	38.013	Up-regulation
CMGC_MAPK_p38_MAPK13_ST	P30281	CCND3	O15264	MAPK13	T283	T283I	283	Missense	central	0	yes	47.606	0.000	PhosphoSitePlus	COSMIC;GDSC;CCLE	38.013	Loss
CMGC_MAPK_p38_MAPK13_ST	P30281	CCND3	O15264	MAPK13	T283	V287G	287	Missense	distal	4	no	47.606	46.824	PhosphoSitePlus	COSMIC	38.013	Down-regulation
CMGC_MAPK_p38_MAPK13_ST	P30281	CCND3	O15264	MAPK13	T283	P284R	284	Missense	proximal	1	no	47.606	35.559	PhosphoSitePlus	COSMIC	38.013	Loss
CMGC_MAPK_p38_MAPK13_ST	P30281	CCND3	O15264	MAPK13	T283	D286G	286	Missense	distal	3	no	47.606	47.564	PhosphoSitePlus	COSMIC	38.013	Down-regulation
CMGC_MAPK_p38_MAPK13_ST	P30281	CCND3	O15264	MAPK13	T283	V287D	287	Missense	distal	4	no	47.606	47.841	PhosphoSitePlus	COSMIC;CCLE	38.013	Up-regulation
CMGC_MAPK_p38_MAPK13_ST	P30281	CCND3	O15264	MAPK13	T283	P284T	284	Missense	proximal	1	no	47.606	25.530	PhosphoSitePlus	COSMIC	38.013	Loss
CMGC_MAPK_p38_MAPK13_ST	P30281	CCND3	O15264	MAPK13	T283	G277W	277	Missense	distal	-6	no	47.606	47.128	PhosphoSitePlus	COSMIC	38.013	Down-regulation
CMGC_MAPK_p38_MAPK13_ST	P30281	CCND3	O15264	MAPK13	T283	A289P	289	Missense	distal	6	no	47.606	47.824	PhosphoSitePlus	COSMIC	38.013	Up-regulation
STE_STE20_NinaC_MYO3A_ST	Q8NEV4	MYO3A	Q8NEV4	MYO3A	T178	R181L	181	Missense	distal	3	no	9.069	9.032	EPSD;PhosphoSitePlus	COSMIC;CCLE	3.030	Down-regulation
STE_STE20_NinaC_MYO3A_ST	Q8NEV4	MYO3A	Q8NEV4	MYO3A	T178	R181S	181	Missense	distal	3	no	9.069	9.080	EPSD;PhosphoSitePlus	COSMIC;GDSC;CCLE	3.030	Up-regulation
STE_STE20_NinaC_MYO3A_ST	Q8NEV4	MYO3A	Q8NEV4	MYO3A	T178	A173S	173	Missense	distal	-5	no	9.069	9.093	EPSD;PhosphoSitePlus	COSMIC	3.030	Up-regulation
STE_STE20_NinaC_MYO3A_ST	Q8NEV4	MYO3A	Q8NEV4	MYO3A	T178	R181C	181	Missense	distal	3	no	9.069	9.056	EPSD;PhosphoSitePlus	COSMIC	3.030	Down-regulation
STE_STE20_NinaC_MYO3A_ST	Q8NEV4	MYO3A	Q8NEV4	MYO3A	T178	T178I	178	Missense	central	0	yes	9.069	0.000	EPSD;PhosphoSitePlus	COSMIC	3.030	Loss
STE_STE20_NinaC_MYO3A_ST	Q8NEV4	MYO3A	Q8NEV4	MYO3A	T184	R181L	181	Missense	distal	-3	no	8.742	8.672	EPSD;PhosphoSitePlus	COSMIC;CCLE	3.030	Down-regulation
STE_STE20_NinaC_MYO3A_ST	Q8NEV4	MYO3A	Q8NEV4	MYO3A	T184	R181S	181	Missense	distal	-3	no	8.742	8.714	EPSD;PhosphoSitePlus	COSMIC;GDSC;CCLE	3.030	Down-regulation
STE_STE20_NinaC_MYO3A_ST	Q8NEV4	MYO3A	Q8NEV4	MYO3A	T184	P189L	189	Missense	distal	5	no	8.742	8.738	EPSD;PhosphoSitePlus	COSMIC	3.030	Down-regulation
STE_STE20_NinaC_MYO3A_ST	Q8NEV4	MYO3A	Q8NEV4	MYO3A	T184	R181C	181	Missense	distal	-3	no	8.742	8.674	EPSD;PhosphoSitePlus	COSMIC	3.030	Down-regulation
STE_STE20_NinaC_MYO3A_ST	Q8NEV4	MYO3A	Q8NEV4	MYO3A	T184	T178I	178	Missense	distal	-6	no	8.742	8.459	EPSD;PhosphoSitePlus	COSMIC	3.030	Down-regulation
STE_STE20_NinaC_MYO3A_ST	Q8NEV4	MYO3A	Q8NEV4	MYO3A	S335	S335Y	335	Missense	central	0	yes	3.416	0.000	EPSD	COSMIC	3.030	Loss
STE_STE20_NinaC_MYO3A_ST	Q8NEV4	MYO3A	Q8NEV4	MYO3A	S335	S335F	335	Missense	central	0	yes	3.416	0.000	EPSD	COSMIC	3.030	Loss
STE_STE20_NinaC_MYO3A_ST	Q8NEV4	MYO3A	Q8NEV4	MYO3A	T908	N902T	902	Missense	distal	-6	no	8.285	8.489	EPSD;PhosphoSitePlus	COSMIC;GDSC	3.030	Up-regulation
STE_STE20_NinaC_MYO3A_ST	Q8NEV4	MYO3A	Q8NEV4	MYO3A	T908	H914N	914	Missense	distal	6	no	8.285	8.286	EPSD;PhosphoSitePlus	COSMIC;GDSC;CCLE	3.030	Up-regulation
STE_STE20_NinaC_MYO3A_ST	Q8NEV4	MYO3A	Q8NEV4	MYO3A	T908	A904S	904	Missense	distal	-4	no	8.285	8.307	EPSD;PhosphoSitePlus	COSMIC	3.030	Up-regulation
STE_STE20_NinaC_MYO3A_ST	Q8NEV4	MYO3A	Q8NEV4	MYO3A	T919	H914N	914	Missense	distal	-5	no	9.799	9.835	PhosphoSitePlus;EPSD	COSMIC;GDSC;CCLE	3.030	Up-regulation
STE_STE20_NinaC_MYO3A_ST	Q8NEV4	MYO3A	Q8NEV4	MYO3A	T919	Q924H	924	Missense	distal	5	no	9.799	9.801	PhosphoSitePlus;EPSD	COSMIC;GDSC;CCLE	3.030	Up-regulation
TK_Src_SrcA_FYN_Y	Q12879	GRIN2A	P06241	FYN	Y698	P699T	699	Missense	proximal	1	no	2.935	3.828	EPSD	COSMIC	3.469	Gain
TK_Src_SrcA_FYN_Y	Q12879	GRIN2A	P06241	FYN	Y730	A733S	733	Missense	distal	3	no	3.858	4.633	EPSD	COSMIC	3.469	Up-regulation
TK_Src_SrcA_FYN_Y	Q12879	GRIN2A	P06241	FYN	Y730	A727V	727	Missense	distal	-3	no	3.858	2.961	EPSD	COSMIC	3.469	Loss
TK_Src_SrcA_FYN_Y	Q12879	GRIN2A	P06241	FYN	Y730	A727S	727	Missense	distal	-3	no	3.858	3.585	EPSD	COSMIC	3.469	Down-regulation
TK_Src_SrcA_FYN_Y	Q12879	GRIN2A	P06241	FYN	Y730	G723V	723	Missense	distal	-7	no	3.858	4.187	EPSD	COSMIC	3.469	Up-regulation
TK_Src_SrcA_FYN_Y	Q12879	GRIN2A	P06241	FYN	Y730	A732V	732	Missense	proximal	2	no	3.858	3.463	EPSD	COSMIC	3.469	Loss
TK_Src_SrcA_FYN_Y	Q12879	GRIN2A	P06241	FYN	Y1118	T1119I	1119	Missense	proximal	1	no	3.737	3.170	PhosphoSitePlus;EPSD	COSMIC	3.469	Loss
TK_Src_SrcA_FYN_Y	Q12879	GRIN2A	P06241	FYN	Y1118	G1122S	1122	Missense	distal	4	no	3.737	3.913	PhosphoSitePlus;EPSD	COSMIC	3.469	Up-regulation
TK_Src_SrcA_FYN_Y	Q12879	GRIN2A	P06241	FYN	Y1118	S1111R	1111	Missense	distal	-7	no	3.737	4.410	PhosphoSitePlus;EPSD	COSMIC	3.469	Up-regulation
TK_Src_SrcA_FYN_Y	Q12879	GRIN2A	P06241	FYN	Y1118	P1113S	1113	Missense	distal	-5	no	3.737	3.582	PhosphoSitePlus;EPSD	COSMIC	3.469	Down-regulation
TK_Src_SrcA_FYN_Y	Q12879	GRIN2A	P06241	FYN	Y1118	G1122C	1122	Missense	distal	4	no	3.737	3.747	PhosphoSitePlus;EPSD	COSMIC	3.469	Up-regulation
TK_Src_SrcA_FYN_Y	Q12879	GRIN2A	P06241	FYN	Y1118	T1119P	1119	Missense	proximal	1	no	3.737	2.844	PhosphoSitePlus;EPSD	COSMIC	3.469	Loss
TK_Src_SrcA_FYN_Y	Q12879	GRIN2A	P06241	FYN	Y1118	R1114I	1114	Missense	distal	-4	no	3.737	3.051	PhosphoSitePlus;EPSD	COSMIC	3.469	Loss
TK_Src_SrcA_FYN_Y	Q12879	GRIN2A	P06241	FYN	Y1118	T1119N	1119	Missense	proximal	1	no	3.737	3.761	PhosphoSitePlus;EPSD	COSMIC	3.469	Up-regulation
TK_Src_SrcA_FYN_Y	Q12879	GRIN2A	P06241	FYN	Y1118	K1116R	1116	Missense	proximal	-2	no	3.737	3.707	PhosphoSitePlus;EPSD	COSMIC	3.469	Down-regulation
TK_Src_SrcA_FYN_Y	Q12879	GRIN2A	P06241	FYN	Y1118	K1124N	1124	Missense	distal	6	no	3.737	3.903	PhosphoSitePlus;EPSD	COSMIC	3.469	Up-regulation
TK_Src_SrcA_FYN_Y	Q12879	GRIN2A	P06241	FYN	Y1118	K1116N	1116	Missense	proximal	-2	no	3.737	4.436	PhosphoSitePlus;EPSD	COSMIC;GDSC;CCLE	3.469	Up-regulation
TK_Src_SrcA_FYN_Y	Q12879	GRIN2A	P06241	FYN	Y1187	K1189N	1189	Missense	proximal	2	no	4.093	4.634	EPSD;PhosphoSitePlus	COSMIC	3.469	Up-regulation
TK_Src_SrcA_FYN_Y	Q12879	GRIN2A	P06241	FYN	Y1187	D1182Y	1182	Missense	distal	-5	no	4.093	2.724	EPSD;PhosphoSitePlus	COSMIC	3.469	Loss
TK_Src_SrcA_FYN_Y	Q12879	GRIN2A	P06241	FYN	Y1187	K1185T	1185	Missense	proximal	-2	no	4.093	5.023	EPSD;PhosphoSitePlus	COSMIC	3.469	Up-regulation
TK_Src_SrcA_FYN_Y	Q12879	GRIN2A	P06241	FYN	Y1187	F1191C	1191	Missense	distal	4	no	4.093	4.088	EPSD;PhosphoSitePlus	COSMIC	3.469	Down-regulation
TK_Src_SrcA_FYN_Y	Q12879	GRIN2A	P06241	FYN	Y1187	H1190Y	1190	Missense	distal	3	no	4.093	3.958	EPSD;PhosphoSitePlus	COSMIC	3.469	Down-regulation
TK_Src_SrcA_FYN_Y	Q12879	GRIN2A	P06241	FYN	Y1187	L1193W	1193	Missense	distal	6	no	4.093	4.358	EPSD;PhosphoSitePlus	COSMIC	3.469	Up-regulation
TK_Src_SrcA_FYN_Y	Q12879	GRIN2A	P06241	FYN	Y1187	F1191I	1191	Missense	distal	4	no	4.093	3.959	EPSD;PhosphoSitePlus	COSMIC	3.469	Down-regulation
TK_Src_SrcA_FYN_Y	Q12879	GRIN2A	P06241	FYN	Y1246	D1247N	1247	Missense	proximal	1	no	4.092	3.221	EPSD;PhosphoSitePlus	COSMIC	3.469	Loss
TK_Src_SrcA_FYN_Y	Q12879	GRIN2A	P06241	FYN	Y1246	D1249N	1249	Missense	distal	3	no	4.092	4.792	EPSD;PhosphoSitePlus	COSMIC	3.469	Up-regulation
TK_Src_SrcA_FYN_Y	Q12879	GRIN2A	P06241	FYN	Y1246	Q1252K	1252	Missense	distal	6	no	4.092	3.698	EPSD;PhosphoSitePlus	COSMIC	3.469	Down-regulation
TK_Src_SrcA_FYN_Y	Q12879	GRIN2A	P06241	FYN	Y1246	L1240P	1240	Missense	distal	-6	no	4.092	3.896	EPSD;PhosphoSitePlus	COSMIC	3.469	Down-regulation
TK_Src_SrcA_FYN_Y	Q12879	GRIN2A	P06241	FYN	Y1267	G1263E	1263	Missense	distal	-4	no	7.932	9.428	EPSD;PhosphoSitePlus	COSMIC	3.469	Up-regulation
TK_Src_SrcA_FYN_Y	Q12879	GRIN2A	P06241	FYN	Y1267	P1260Q	1260	Missense	distal	-7	no	7.932	7.483	EPSD;PhosphoSitePlus	COSMIC	3.469	Down-regulation
TK_Src_SrcA_FYN_Y	Q12879	GRIN2A	P06241	FYN	Y1267	W1271G	1271	Missense	distal	4	no	7.932	8.145	EPSD;PhosphoSitePlus	COSMIC	3.469	Up-regulation
TK_Src_SrcA_FYN_Y	Q12879	GRIN2A	P06241	FYN	Y1267	E1264D	1264	Missense	distal	-3	no	7.932	8.388	EPSD;PhosphoSitePlus	COSMIC	3.469	Up-regulation
TK_Src_SrcA_FYN_Y	Q12879	GRIN2A	P06241	FYN	Y1292	H1290N	1290	Missense	proximal	-2	no	5.278	5.953	EPSD	COSMIC	3.469	Up-regulation
TK_Src_SrcA_FYN_Y	Q12879	GRIN2A	P06241	FYN	Y1292	R1285K	1285	Missense	distal	-7	no	5.278	4.276	EPSD	COSMIC	3.469	Down-regulation
TK_Src_SrcA_FYN_Y	Q12879	GRIN2A	P06241	FYN	Y1292	N1294K	1294	Missense	proximal	2	no	5.278	4.737	EPSD	COSMIC	3.469	Down-regulation
TK_Src_SrcA_FYN_Y	Q12879	GRIN2A	P06241	FYN	Y1325	R1318W	1318	Missense	distal	-7	no	3.797	1.668	EPSD;PhosphoSitePlus	COSMIC	3.469	Loss
TK_Src_SrcA_FYN_Y	Q12879	GRIN2A	P06241	FYN	Y1325	L1320M	1320	Missense	distal	-5	no	3.797	4.233	EPSD;PhosphoSitePlus	COSMIC	3.469	Up-regulation
TK_Src_SrcA_FYN_Y	Q12879	GRIN2A	P06241	FYN	Y1325	G1326S	1326	Missense	proximal	1	no	3.797	3.038	EPSD;PhosphoSitePlus	COSMIC	3.469	Loss
TK_Src_SrcA_FYN_Y	Q12879	GRIN2A	P06241	FYN	Y1325	L1320P	1320	Missense	distal	-5	no	3.797	4.234	EPSD;PhosphoSitePlus	COSMIC	3.469	Up-regulation
TK_Src_SrcA_FYN_Y	Q12879	GRIN2A	P06241	FYN	Y1325	N1323Y	1323	Missense	proximal	-2	no	3.797	3.638	EPSD;PhosphoSitePlus	COSMIC	3.469	Down-regulation
TK_Src_SrcA_FYN_Y	Q12879	GRIN2A	P06241	FYN	Y1325	F1329L	1329	Missense	distal	4	no	3.797	3.854	EPSD;PhosphoSitePlus	COSMIC	3.469	Up-regulation
TK_Src_SrcA_FYN_Y	Q12879	GRIN2A	P06241	FYN	Y1325	G1326V	1326	Missense	proximal	1	no	3.797	2.281	EPSD;PhosphoSitePlus	COSMIC	3.469	Loss
TK_Src_SrcA_FYN_Y	Q96J02	ITCH	P06241	FYN	Y375	R373H	373	Missense	proximal	-2	no	4.683	4.737	EPSD	COSMIC	3.469	Up-regulation
TK_Src_SrcA_FYN_Y	Q96J02	ITCH	P06241	FYN	Y375	N370K	370	Missense	distal	-5	no	4.683	5.138	EPSD	COSMIC	3.469	Up-regulation
TK_Src_SrcA_FYN_Y	Q96J02	ITCH	P06241	FYN	Y375	H379R	379	Missense	distal	4	no	4.683	4.752	EPSD	COSMIC;CCLE	3.469	Up-regulation
TK_Src_SrcA_FYN_Y	Q96J02	ITCH	P06241	FYN	Y375	H379D	379	Missense	distal	4	no	4.683	4.620	EPSD	COSMIC	3.469	Down-regulation
TK_Src_SrcA_FYN_Y	Q96J02	ITCH	P06241	FYN	Y420	Q413H	413	Missense	distal	-7	no	4.897	3.698	PhosphoSitePlus	COSMIC	3.469	Down-regulation
TK_Src_SrcA_FYN_Y	Q96J02	ITCH	P06241	FYN	Y420	G421V	421	Missense	proximal	1	no	4.897	3.381	PhosphoSitePlus	COSMIC	3.469	Loss
TK_Src_SrcA_FYN_Y	Q96J02	ITCH	P06241	FYN	Y420	D424N	424	Missense	distal	4	no	4.897	5.152	PhosphoSitePlus	COSMIC	3.469	Up-regulation
TK_Src_SrcA_FYN_Y	Q96J02	ITCH	P06241	FYN	Y495	F496L	496	Missense	proximal	1	no	3.984	4.906	EPSD	COSMIC	3.469	Up-regulation
TK_Src_SrcA_FYN_Y	Q96J02	ITCH	P06241	FYN	Y495	R501I	501	Missense	distal	6	no	3.984	4.356	EPSD	COSMIC	3.469	Up-regulation
TK_Src_SrcA_FYN_Y	Q96J02	ITCH	P06241	FYN	Y589	E584K	584	Missense	distal	-5	no	3.629	3.779	EPSD	COSMIC	3.469	Up-regulation
TK_Src_SrcA_FYN_Y	Q96J02	ITCH	P06241	FYN	Y589	E595D	595	Missense	distal	6	no	3.629	3.694	EPSD	COSMIC	3.469	Up-regulation
TK_Src_SrcA_FYN_Y	Q96J02	ITCH	P06241	FYN	Y589	E585K	585	Missense	distal	-4	no	3.629	2.859	EPSD	COSMIC	3.469	Loss
TK_Src_SrcA_FYN_Y	P06127	CD5	P06241	FYN	Y51	G46S	46	Missense	distal	-5	no	3.899	3.905	EPSD	COSMIC	3.469	Up-regulation
TK_Src_SrcA_FYN_Y	P06127	CD5	P06241	FYN	Y453	D450N	450	Missense	distal	-3	no	6.493	5.930	PhosphoSitePlus;EPSD	COSMIC	3.469	Down-regulation
TK_Src_SrcA_FYN_Y	O15117	FYB1	P06241	FYN	Y387	T389P	389	Missense	proximal	2	no	3.667	3.066	EPSD	COSMIC	3.469	Loss
TK_Src_SrcA_FYN_Y	O15117	FYB1	P06241	FYN	Y387	S386T	386	Missense	proximal	-1	no	3.667	4.910	EPSD	COSMIC	3.469	Up-regulation
TK_Src_SrcA_FYN_Y	O15117	FYB1	P06241	FYN	Y387	Y387C	387	Missense	central	0	yes	3.667	0.000	EPSD	COSMIC	3.469	Loss
TK_Src_SrcA_FYN_Y	O15117	FYB1	P06241	FYN	Y387	S388L	388	Missense	proximal	1	no	3.667	2.796	EPSD	COSMIC	3.469	Loss
TK_Src_SrcA_FYN_Y	O15117	FYB1	P06241	FYN	Y387	G383C	383	Missense	distal	-4	no	3.667	2.567	EPSD	COSMIC	3.469	Loss
TK_Src_SrcA_FYN_Y	O15117	FYB1	P06241	FYN	Y387	S391F	391	Missense	distal	4	no	3.667	3.505	EPSD	COSMIC	3.469	Down-regulation
TK_Src_SrcA_FYN_Y	O15117	FYB1	P06241	FYN	Y462	D456G	456	Missense	distal	-6	no	5.256	4.392	EPSD	COSMIC	3.469	Down-regulation
TK_Src_SrcA_FYN_Y	O15117	FYB1	P06241	FYN	Y462	Y462F	462	Missense	central	0	yes	5.256	0.000	EPSD	COSMIC	3.469	Loss
TK_Src_SrcA_FYN_Y	O15117	FYB1	P06241	FYN	Y462	I465K	465	Missense	distal	3	no	5.256	4.132	EPSD	COSMIC	3.469	Down-regulation
TK_Src_SrcA_FYN_Y	O15117	FYB1	P06241	FYN	Y462	D464Y	464	Missense	proximal	2	no	5.256	4.332	EPSD	COSMIC	3.469	Down-regulation
TK_Src_SrcA_FYN_Y	O15117	FYB1	P06241	FYN	Y462	E466K	466	Missense	distal	4	no	5.256	5.480	EPSD	COSMIC	3.469	Up-regulation
TK_Src_SrcA_FYN_Y	O15117	FYB1	P06241	FYN	Y462	E463A	463	Missense	proximal	1	no	5.256	4.679	EPSD	COSMIC	3.469	Down-regulation
TK_Src_SrcA_FYN_Y	O15117	FYB1	P06241	FYN	Y559	A555P	555	Missense	distal	-4	no	4.671	4.768	EPSD;PhosphoSitePlus	COSMIC	3.469	Up-regulation
TK_Src_SrcA_FYN_Y	O15117	FYB1	P06241	FYN	Y559	A566V	566	Missense	distal	7	no	4.671	4.626	EPSD;PhosphoSitePlus	COSMIC	3.469	Down-regulation
TK_Src_SrcA_FYN_Y	O15117	FYB1	P06241	FYN	Y559	A555S	555	Missense	distal	-4	no	4.671	4.952	EPSD;PhosphoSitePlus	COSMIC	3.469	Up-regulation
TK_Src_SrcA_FYN_Y	O15117	FYB1	P06241	FYN	Y559	S558L	558	Missense	proximal	-1	no	4.671	6.037	EPSD;PhosphoSitePlus	COSMIC	3.469	Up-regulation
TK_Src_SrcA_FYN_Y	O15117	FYB1	P06241	FYN	Y559	R556M	556	Missense	distal	-3	no	4.671	4.789	EPSD;PhosphoSitePlus	COSMIC	3.469	Up-regulation
TK_Src_SrcA_FYN_Y	O15117	FYB1	P06241	FYN	Y559	G557S	557	Missense	proximal	-2	no	4.671	4.386	EPSD;PhosphoSitePlus	COSMIC	3.469	Down-regulation
TK_Src_SrcA_FYN_Y	O15117	FYB1	P06241	FYN	Y559	R556S	556	Missense	distal	-3	no	4.671	5.216	EPSD;PhosphoSitePlus	COSMIC	3.469	Up-regulation
TK_Src_SrcA_FYN_Y	O15117	FYB1	P06241	FYN	Y571	L576P	576	Missense	distal	5	no	3.222	3.478	EPSD;PhosphoSitePlus	COSMIC	3.469	Gain
TK_Src_SrcA_FYN_Y	O15117	FYB1	P06241	FYN	Y571	A566V	566	Missense	distal	-5	no	3.222	3.709	EPSD;PhosphoSitePlus	COSMIC	3.469	Gain
TK_Src_SrcA_FYN_Y	O15117	FYB1	P06241	FYN	Y595	D591N	591	Missense	distal	-4	no	10.261	8.982	EPSD;PhosphoSitePlus	COSMIC	3.469	Down-regulation
TK_Src_SrcA_FYN_Y	O15117	FYB1	P06241	FYN	Y595	D590N	590	Missense	distal	-5	no	10.261	9.878	EPSD;PhosphoSitePlus	COSMIC	3.469	Down-regulation
TK_Src_SrcA_FYN_Y	O15117	FYB1	P06241	FYN	Y595	E600Q	600	Missense	distal	5	no	10.261	10.523	EPSD;PhosphoSitePlus	COSMIC	3.469	Up-regulation
TK_Src_SrcA_FYN_Y	O15117	FYB1	P06241	FYN	Y595	D597N	597	Missense	proximal	2	no	10.261	10.378	EPSD;PhosphoSitePlus	COSMIC;GDSC	3.469	Up-regulation
TK_Src_SrcA_FYN_Y	O15117	FYB1	P06241	FYN	Y625	I624N	624	Missense	proximal	-1	no	10.080	9.167	EPSD;PhosphoSitePlus	COSMIC	3.469	Down-regulation
TK_Src_SrcA_FYN_Y	O15117	FYB1	P06241	FYN	Y625	P620S	620	Missense	distal	-5	no	10.080	9.925	EPSD;PhosphoSitePlus	COSMIC	3.469	Down-regulation
TK_Src_SrcA_FYN_Y	O15117	FYB1	P06241	FYN	Y625	P618S	618	Missense	distal	-7	no	10.080	9.216	EPSD;PhosphoSitePlus	COSMIC	3.469	Down-regulation
TK_Src_SrcA_FYN_Y	O15117	FYB1	P06241	FYN	Y625	D632V	632	Missense	distal	7	no	10.080	10.057	EPSD;PhosphoSitePlus	COSMIC	3.469	Down-regulation
TK_Src_SrcA_FYN_Y	O15117	FYB1	P06241	FYN	Y625	P620L	620	Missense	distal	-5	no	10.080	9.644	EPSD;PhosphoSitePlus	COSMIC	3.469	Down-regulation
TK_Src_SrcA_FYN_Y	O15117	FYB1	P06241	FYN	Y625	D621G	621	Missense	distal	-4	no	10.080	7.724	EPSD;PhosphoSitePlus	COSMIC	3.469	Down-regulation
TK_Src_SrcA_FYN_Y	O15117	FYB1	P06241	FYN	Y651	G647A	647	Missense	distal	-4	no	5.028	5.207	PhosphoSitePlus;EPSD	COSMIC	3.469	Up-regulation
TK_Src_SrcA_FYN_Y	O15117	FYB1	P06241	FYN	Y651	E649K	649	Missense	proximal	-2	no	5.028	4.397	PhosphoSitePlus;EPSD	COSMIC	3.469	Down-regulation
TK_Src_SrcA_FYN_Y	O15117	FYB1	P06241	FYN	Y651	D645Y	645	Missense	distal	-6	no	5.028	3.159	PhosphoSitePlus;EPSD	COSMIC	3.469	Loss
TK_Src_SrcA_FYN_Y	O15117	FYB1	P06241	FYN	Y651	D658H	658	Missense	distal	7	no	5.028	4.987	PhosphoSitePlus;EPSD	COSMIC	3.469	Down-regulation
TK_Src_SrcA_FYN_Y	O15117	FYB1	P06241	FYN	Y755	R760W	760	Missense	distal	5	no	4.624	3.764	EPSD;PhosphoSitePlus	COSMIC	3.469	Down-regulation
TK_Src_SrcA_FYN_Y	O15117	FYB1	P06241	FYN	Y755	G756C	756	Missense	proximal	1	no	4.624	1.417	EPSD;PhosphoSitePlus	COSMIC	3.469	Loss
TK_Src_SrcA_FYN_Y	O15117	FYB1	P06241	FYN	Y755	L759I	759	Missense	distal	4	no	4.624	4.433	EPSD;PhosphoSitePlus	COSMIC	3.469	Down-regulation
TK_Src_SrcA_FYN_Y	O15117	FYB1	P06241	FYN	Y755	V758F	758	Missense	distal	3	no	4.624	3.894	EPSD;PhosphoSitePlus	COSMIC	3.469	Down-regulation
TK_Src_SrcA_FYN_Y	O15117	FYB1	P06241	FYN	Y755	L759F	759	Missense	distal	4	no	4.624	4.566	EPSD;PhosphoSitePlus	COSMIC	3.469	Down-regulation
TK_Src_SrcA_FYN_Y	O15117	FYB1	P06241	FYN	Y755	K754T	754	Missense	proximal	-1	no	4.624	5.465	EPSD;PhosphoSitePlus	COSMIC	3.469	Up-regulation
TK_Src_SrcA_FYN_Y	O15117	FYB1	P06241	FYN	Y771	A764E	764	Missense	distal	-7	no	9.517	9.993	EPSD;PhosphoSitePlus	COSMIC	3.469	Up-regulation
TK_Src_SrcA_FYN_Y	O15117	FYB1	P06241	FYN	Y771	Y771C	771	Missense	central	0	yes	9.517	0.000	EPSD;PhosphoSitePlus	COSMIC	3.469	Loss
TK_Src_SrcA_FYN_Y	O15117	FYB1	P06241	FYN	Y771	N766S	766	Missense	distal	-5	no	9.517	9.119	EPSD;PhosphoSitePlus	COSMIC	3.469	Down-regulation
TK_Src_SrcA_FYN_Y	O15117	FYB1	P06241	FYN	Y771	D765N	765	Missense	distal	-6	no	9.517	8.675	EPSD;PhosphoSitePlus	COSMIC	3.469	Down-regulation
TK_Src_SrcA_FYN_Y	O15117	FYB1	P06241	FYN	Y771	D773A	773	Missense	proximal	2	no	9.517	9.086	EPSD;PhosphoSitePlus	COSMIC	3.469	Down-regulation
TK_Src_SrcA_FYN_Y	O15117	FYB1	P06241	FYN	Y780	N782Y	782	Missense	proximal	2	no	5.454	4.412	EPSD;PhosphoSitePlus	COSMIC	3.469	Down-regulation
TK_Src_SrcA_FYN_Y	O15117	FYB1	P06241	FYN	Y780	D773A	773	Missense	distal	-7	no	5.454	5.348	EPSD;PhosphoSitePlus	COSMIC	3.469	Down-regulation
TK_Src_SrcA_FYN_Y	P16885	PLCG2	P06241	FYN	Y753	M758I	758	Missense	distal	5	no	7.406	7.146	PhosphoSitePlus;EPSD	COSMIC	3.469	Down-regulation
TK_Src_SrcA_FYN_Y	P16885	PLCG2	P06241	FYN	Y753	S751F	751	Missense	proximal	-2	no	7.406	6.955	PhosphoSitePlus;EPSD	COSMIC	3.469	Down-regulation
TK_Src_SrcA_FYN_Y	P16885	PLCG2	P06241	FYN	Y759	P762L	762	Missense	distal	3	no	3.649	3.115	EPSD;PhosphoSitePlus	COSMIC	3.469	Loss
TK_Src_SrcA_FYN_Y	P16885	PLCG2	P06241	FYN	Y759	M758I	758	Missense	proximal	-1	no	3.649	4.419	EPSD;PhosphoSitePlus	COSMIC	3.469	Up-regulation
TK_Src_SrcA_FYN_Y	P16885	PLCG2	P06241	FYN	Y778	T773I	773	Missense	distal	-5	no	7.017	5.701	EPSD	COSMIC	3.469	Down-regulation
TK_Src_SrcA_FYN_Y	P16885	PLCG2	P06241	FYN	Y778	R772K	772	Missense	distal	-6	no	7.017	7.153	EPSD	COSMIC	3.469	Up-regulation
TK_Src_SrcA_FYN_Y	P16885	PLCG2	P06241	FYN	Y778	A776T	776	Missense	proximal	-2	no	7.017	6.904	EPSD	COSMIC	3.469	Down-regulation
TK_Src_SrcA_FYN_Y	P16885	PLCG2	P06241	FYN	Y778	R784Q	784	Missense	distal	6	no	7.017	7.208	EPSD	COSMIC	3.469	Up-regulation
TK_Src_SrcA_FYN_Y	P16885	PLCG2	P06241	FYN	Y1048	E1041Q	1041	Missense	distal	-7	no	6.165	5.875	EPSD	COSMIC	3.469	Down-regulation
TK_Src_SrcA_FYN_Y	P16885	PLCG2	P06241	FYN	Y1048	E1041K	1041	Missense	distal	-7	no	6.165	5.130	EPSD	COSMIC	3.469	Down-regulation
TK_Src_SrcA_FYN_Y	P16885	PLCG2	P06241	FYN	Y1048	E1054Q	1054	Missense	distal	6	no	6.165	6.292	EPSD	COSMIC	3.469	Up-regulation
TK_Src_SrcA_FYN_Y	P00519	ABL1	P06241	FYN	Y70	G76E	76	Missense	distal	6	no	3.491	3.617	EPSD;PhosphoSitePlus	COSMIC	3.469	Up-regulation
TK_Src_SrcA_FYN_Y	P00519	ABL1	P06241	FYN	Y70	D77E	77	Missense	distal	7	no	3.491	3.534	EPSD;PhosphoSitePlus	COSMIC	3.469	Up-regulation
TK_Src_SrcA_FYN_Y	P00519	ABL1	P06241	FYN	Y70	S75G	75	Missense	distal	5	no	3.491	3.409	EPSD;PhosphoSitePlus	COSMIC	3.469	Loss
TK_Src_SrcA_FYN_Y	P00519	ABL1	P06241	FYN	Y70	V67I	67	Missense	distal	-3	no	3.491	2.177	EPSD;PhosphoSitePlus	COSMIC	3.469	Loss
TK_Src_SrcA_FYN_Y	P00519	ABL1	P06241	FYN	Y115	G109V	109	Missense	distal	-6	no	3.603	3.477	EPSD;PhosphoSitePlus	COSMIC	3.469	Down-regulation
TK_Src_SrcA_FYN_Y	P00519	ABL1	P06241	FYN	Y128	K124N	124	Missense	distal	-4	no	4.824	5.175	EPSD;PhosphoSitePlus	COSMIC	3.469	Up-regulation
TK_Src_SrcA_FYN_Y	P00519	ABL1	P06241	FYN	Y128	P131L	131	Missense	distal	3	no	4.824	4.290	EPSD;PhosphoSitePlus	COSMIC	3.469	Down-regulation
TK_Src_SrcA_FYN_Y	P00519	ABL1	P06241	FYN	Y128	R134H	134	Missense	distal	6	no	4.824	5.084	EPSD;PhosphoSitePlus	COSMIC	3.469	Up-regulation
TK_Src_SrcA_FYN_Y	P00519	ABL1	P06241	FYN	Y139	G144E	144	Missense	distal	5	no	6.772	7.011	EPSD;PhosphoSitePlus	COSMIC	3.469	Up-regulation
TK_Src_SrcA_FYN_Y	P00519	ABL1	P06241	FYN	Y139	A137S	137	Missense	proximal	-2	no	6.772	6.529	EPSD;PhosphoSitePlus	COSMIC	3.469	Down-regulation
TK_Src_SrcA_FYN_Y	P00519	ABL1	P06241	FYN	Y139	R134H	134	Missense	distal	-5	no	6.772	6.209	EPSD;PhosphoSitePlus	COSMIC	3.469	Down-regulation
TK_Src_SrcA_FYN_Y	P00519	ABL1	P06241	FYN	Y172	R166K	166	Missense	distal	-6	no	8.367	8.503	EPSD;PhosphoSitePlus	COSMIC;CCLE	3.469	Up-regulation
TK_Src_SrcA_FYN_Y	P00519	ABL1	P06241	FYN	Y172	E168K	168	Missense	distal	-4	no	8.367	7.597	EPSD;PhosphoSitePlus	COSMIC	3.469	Down-regulation
TK_Src_SrcA_FYN_Y	P00519	ABL1	P06241	FYN	Y172	Y167H	167	Missense	distal	-5	no	8.367	8.779	EPSD;PhosphoSitePlus	COSMIC	3.469	Up-regulation
TK_Src_SrcA_FYN_Y	P00519	ABL1	P06241	FYN	Y185	R191C	191	Missense	distal	6	no	4.806	5.509	EPSD;PhosphoSitePlus	COSMIC	3.469	Up-regulation
TK_Src_SrcA_FYN_Y	P00519	ABL1	P06241	FYN	Y185	S187F	187	Missense	proximal	2	no	4.806	4.758	EPSD;PhosphoSitePlus	COSMIC	3.469	Down-regulation
TK_Src_SrcA_FYN_Y	P00519	ABL1	P06241	FYN	Y185	L184R	184	Missense	proximal	-1	no	4.806	2.455	EPSD;PhosphoSitePlus	COSMIC	3.469	Loss
TK_Src_SrcA_FYN_Y	P00519	ABL1	P06241	FYN	Y215	R220H	220	Missense	distal	5	no	4.580	4.096	EPSD;PhosphoSitePlus	COSMIC	3.469	Down-regulation
TK_Src_SrcA_FYN_Y	P00519	ABL1	P06241	FYN	Y215	P218S	218	Missense	distal	3	no	4.580	3.990	EPSD;PhosphoSitePlus	COSMIC	3.469	Down-regulation
TK_Src_SrcA_FYN_Y	P00519	ABL1	P06241	FYN	Y215	T212R	212	Missense	distal	-3	no	4.580	3.330	EPSD;PhosphoSitePlus	COSMIC	3.469	Loss
TK_Src_SrcA_FYN_Y	P00519	ABL1	P06241	FYN	Y253	Q252M	252	Missense	proximal	-1	no	2.062	3.571	EPSD	COSMIC	3.469	Gain
TK_Src_SrcA_FYN_Y	P00519	ABL1	P06241	FYN	Y253	Q252P	252	Missense	proximal	-1	no	2.062	3.618	EPSD	COSMIC	3.469	Gain
TK_Src_SrcA_FYN_Y	P00519	ABL1	P06241	FYN	Y253	H246R	246	Missense	distal	-7	no	2.062	3.518	EPSD	COSMIC	3.469	Gain
TK_Src_SrcA_FYN_Y	P00519	ABL1	P06241	FYN	Y257	Y253H	253	Missense	distal	-4	no	1.864	3.819	EPSD	COSMIC	3.469	Gain
TK_Src_SrcA_FYN_Y	P00519	ABL1	P06241	FYN	Y320	F317V	317	Missense	distal	-3	no	2.087	3.932	EPSD	COSMIC	3.469	Gain
TK_Src_SrcA_FYN_Y	P00519	ABL1	P06241	FYN	Y320	F317R	317	Missense	distal	-3	no	2.087	4.011	EPSD	COSMIC	3.469	Gain
TK_Src_SrcA_FYN_Y	P00519	ABL1	P06241	FYN	Y320	I313T	313	Missense	distal	-7	no	2.087	3.577	EPSD	COSMIC	3.469	Gain
TK_Src_SrcA_FYN_Y	P00519	ABL1	P06241	FYN	Y393	R386Q	386	Missense	distal	-7	no	7.262	7.006	PhosphoSitePlus;EPSD	COSMIC	3.469	Down-regulation
TK_Src_SrcA_FYN_Y	P00519	ABL1	P06241	FYN	Y393	A397P	397	Missense	distal	4	no	7.262	7.380	PhosphoSitePlus;EPSD	COSMIC	3.469	Up-regulation
TK_Src_SrcA_FYN_Y	P00519	ABL1	P06241	FYN	Y393	H396R	396	Missense	distal	3	no	7.262	8.031	PhosphoSitePlus;EPSD	COSMIC	3.469	Up-regulation
TK_Src_SrcA_FYN_Y	P00519	ABL1	P06241	FYN	Y393	L387M	387	Missense	distal	-6	no	7.262	7.185	PhosphoSitePlus;EPSD	COSMIC	3.469	Down-regulation
TK_Src_SrcA_FYN_Y	P00519	ABL1	P06241	FYN	Y393	M388L	388	Missense	distal	-5	no	7.262	6.826	PhosphoSitePlus;EPSD	COSMIC	3.469	Down-regulation
TK_Src_SrcA_FYN_Y	P00519	ABL1	P06241	FYN	Y393	G398R	398	Missense	distal	5	no	7.262	7.519	PhosphoSitePlus;EPSD	COSMIC	3.469	Up-regulation
TK_Src_SrcA_FYN_Y	P00519	ABL1	P06241	FYN	Y393	A399T	399	Missense	distal	6	no	7.262	7.181	PhosphoSitePlus;EPSD	COSMIC	3.469	Down-regulation
TK_Src_SrcA_FYN_Y	P00519	ABL1	P06241	FYN	Y393	T389A	389	Missense	distal	-4	no	7.262	6.147	PhosphoSitePlus;EPSD	COSMIC	3.469	Down-regulation
TK_Src_SrcA_FYN_Y	P00519	ABL1	P06241	FYN	Y393	K400E	400	Missense	distal	7	no	7.262	7.317	PhosphoSitePlus;EPSD	COSMIC	3.469	Up-regulation
TK_Src_SrcA_FYN_Y	P00519	ABL1	P06241	FYN	Y393	T394A	394	Missense	proximal	1	no	7.262	6.734	PhosphoSitePlus;EPSD	COSMIC	3.469	Down-regulation
TK_Src_SrcA_FYN_Y	P00519	ABL1	P06241	FYN	Y393	H396P	396	Missense	distal	3	no	7.262	8.536	PhosphoSitePlus;EPSD	COSMIC	3.469	Up-regulation
TK_Src_SrcA_FYN_Y	P00519	ABL1	P06241	FYN	Y393	D391N	391	Missense	proximal	-2	no	7.262	7.623	PhosphoSitePlus;EPSD	COSMIC	3.469	Up-regulation
TK_Src_SrcA_FYN_Y	P00519	ABL1	P06241	FYN	Y393	L387F	387	Missense	distal	-6	no	7.262	6.694	PhosphoSitePlus;EPSD	COSMIC	3.469	Down-regulation
TK_Src_SrcA_FYN_Y	P00519	ABL1	P06241	FYN	Y393	H396Y	396	Missense	distal	3	no	7.262	7.127	PhosphoSitePlus;EPSD	COSMIC	3.469	Down-regulation
TK_Src_SrcA_FYN_Y	P00519	ABL1	P06241	FYN	Y393	G390W	390	Missense	distal	-3	no	7.262	3.005	PhosphoSitePlus;EPSD	COSMIC	3.469	Loss
TK_Src_SrcA_FYN_Y	O75051	PLXNA2	P06241	FYN	Y1483	G1479V	1479	Missense	distal	-4	no	3.440	3.778	EPSD	COSMIC	3.469	Gain
TK_Src_SrcA_FYN_Y	O75051	PLXNA2	P06241	FYN	Y1605	K1600E	1600	Missense	distal	-5	no	5.922	5.773	PhosphoSitePlus;EPSD	COSMIC	3.469	Down-regulation
TK_Src_SrcA_FYN_Y	O75051	PLXNA2	P06241	FYN	Y1677	A1683V	1683	Missense	distal	6	no	5.530	5.504	EPSD;PhosphoSitePlus	COSMIC	3.469	Down-regulation
TK_Src_SrcA_FYN_Y	O75051	PLXNA2	P06241	FYN	Y1677	S1674Y	1674	Missense	distal	-3	no	5.530	5.676	EPSD;PhosphoSitePlus	COSMIC	3.469	Up-regulation
TK_Src_SrcA_FYN_Y	O75051	PLXNA2	P06241	FYN	Y1677	L1682V	1682	Missense	distal	5	no	5.530	5.594	EPSD;PhosphoSitePlus	COSMIC	3.469	Up-regulation
TK_Src_SrcA_FYN_Y	Q01628	IFITM3	P06241	FYN	Y20	E25A	25	Missense	distal	5	no	4.247	4.648	PhosphoSitePlus	COSMIC	3.469	Up-regulation
TK_Src_SrcA_FYN_Y	Q01628	IFITM3	P06241	FYN	Y20	Q16K	16	Missense	distal	-4	no	4.247	3.445	PhosphoSitePlus	COSMIC	3.469	Loss
TK_Src_SrcA_FYN_Y	Q01628	IFITM3	P06241	FYN	Y20	H27Q	27	Missense	distal	7	no	4.247	4.281	PhosphoSitePlus	COSMIC;CCLE	3.469	Up-regulation
TK_Src_SrcA_FYN_Y	Q03135	CAV1	P06241	FYN	Y14	H12Q	12	Missense	proximal	-2	no	5.566	5.976	PhosphoSitePlus	COSMIC	3.469	Up-regulation
TK_Src_SrcA_FYN_Y	Q03135	CAV1	P06241	FYN	Y14	Q21L	21	Missense	distal	7	no	5.566	5.545	PhosphoSitePlus	COSMIC	3.469	Down-regulation
TK_Src_SrcA_FYN_Y	Q03135	CAV1	P06241	FYN	Y14	L13H	13	Missense	proximal	-1	no	5.566	5.513	PhosphoSitePlus	COSMIC	3.469	Down-regulation
TK_Src_SrcA_FYN_Y	Q03135	CAV1	P06241	FYN	Y25	Q21L	21	Missense	distal	-4	no	3.942	2.494	EPSD	COSMIC	3.469	Loss
TK_Src_SrcA_FYN_Y	Q03135	CAV1	P06241	FYN	Y42	D43G	43	Missense	proximal	1	no	4.473	4.623	EPSD	COSMIC	3.469	Up-regulation
TK_Src_SrcA_FYN_Y	P52757	CHN2	P06241	FYN	Y55	E48K	48	Missense	distal	-7	no	3.943	2.908	EPSD	COSMIC	3.469	Loss
TK_Src_SrcA_FYN_Y	P52757	CHN2	P06241	FYN	Y55	H61Y	61	Missense	distal	6	no	3.943	3.979	EPSD	COSMIC	3.469	Up-regulation
TK_Src_SrcA_FYN_Y	P52757	CHN2	P06241	FYN	Y55	F60C	60	Missense	distal	5	no	3.943	3.707	EPSD	COSMIC	3.469	Down-regulation
TK_Src_SrcA_FYN_Y	P52757	CHN2	P06241	FYN	Y153	T149I	149	Missense	distal	-4	no	6.106	4.934	EPSD	COSMIC	3.469	Down-regulation
TK_Src_SrcA_FYN_Y	P52757	CHN2	P06241	FYN	Y153	P151T	151	Missense	proximal	-2	no	6.106	6.343	EPSD	COSMIC	3.469	Up-regulation
TK_Src_SrcA_FYN_Y	O14559	ARHGAP33	P06241	FYN	Y406	P399S	399	Missense	distal	-7	no	6.581	5.716	PhosphoSitePlus	COSMIC	3.469	Down-regulation
TK_Src_SrcA_FYN_Y	O14559	ARHGAP33	P06241	FYN	Y406	F409L	409	Missense	distal	3	no	6.581	6.712	PhosphoSitePlus	COSMIC	3.469	Up-regulation
TK_Src_SrcA_FYN_Y	P11274	BCR	P06241	FYN	Y177	E181D	181	Missense	distal	4	no	7.039	6.774	PhosphoSitePlus	COSMIC	3.469	Down-regulation
TK_Src_SrcA_FYN_Y	P11274	BCR	P06241	FYN	Y455	P454S	454	Missense	proximal	-1	no	5.834	4.162	EPSD	COSMIC;CCLE	3.469	Down-regulation
TK_Src_SrcA_FYN_Y	P11274	BCR	P06241	FYN	Y455	L453Q	453	Missense	proximal	-2	no	5.834	6.156	EPSD	COSMIC	3.469	Up-regulation
TK_Src_SrcA_FYN_Y	P11274	BCR	P06241	FYN	Y910	S906F	906	Missense	distal	-4	no	4.120	2.072	EPSD	COSMIC	3.469	Loss
TK_Src_SrcA_FYN_Y	P11274	BCR	P06241	FYN	Y1089	I1088N	1088	Missense	proximal	-1	no	3.515	2.601	EPSD	COSMIC	3.469	Loss
TK_Src_SrcA_FYN_Y	Q9NWQ8	PAG1	P06241	FYN	Y181	E186K	186	Missense	distal	5	no	6.193	6.460	EPSD	COSMIC	3.469	Up-regulation
TK_Src_SrcA_FYN_Y	Q9NWQ8	PAG1	P06241	FYN	Y317	S319L	319	Missense	proximal	2	no	5.123	5.175	PhosphoSitePlus	COSMIC	3.469	Up-regulation
TK_Src_SrcA_FYN_Y	P07766	CD3E	P06241	FYN	Y188	P186T	186	Missense	proximal	-2	no	5.331	5.568	PhosphoSitePlus;EPSD	COSMIC;GDSC;CCLE	3.469	Up-regulation
TK_Src_SrcA_FYN_Y	Q86WV1	SKAP1	P06241	FYN	Y142	G138D	138	Missense	distal	-4	no	2.385	4.742	EPSD	COSMIC	3.469	Gain
TK_Src_SrcA_FYN_Y	Q86WV1	SKAP1	P06241	FYN	Y232	D239H	239	Missense	distal	7	no	7.822	7.782	PhosphoSitePlus;EPSD	COSMIC	3.469	Down-regulation
TK_Src_SrcA_FYN_Y	Q86WV1	SKAP1	P06241	FYN	Y232	D233N	233	Missense	proximal	1	no	7.822	6.951	PhosphoSitePlus;EPSD	COSMIC	3.469	Down-regulation
TK_Src_SrcA_FYN_Y	Q86WV1	SKAP1	P06241	FYN	Y232	D236H	236	Missense	distal	4	no	7.822	7.885	PhosphoSitePlus;EPSD	COSMIC	3.469	Up-regulation
TK_Src_SrcA_FYN_Y	Q86WV1	SKAP1	P06241	FYN	Y232	G237C	237	Missense	distal	5	no	7.822	7.571	PhosphoSitePlus;EPSD	COSMIC;GDSC;CCLE	3.469	Down-regulation
TK_Src_SrcA_FYN_Y	Q86WV1	SKAP1	P06241	FYN	Y232	E229K	229	Missense	distal	-3	no	7.822	7.037	PhosphoSitePlus;EPSD	COSMIC	3.469	Down-regulation
TK_Src_SrcA_FYN_Y	Q86WV1	SKAP1	P06241	FYN	Y271	P275S	275	Missense	distal	4	no	7.181	7.128	EPSD	COSMIC	3.469	Down-regulation
TK_Src_SrcA_FYN_Y	P14923	JUP	P06241	FYN	Y480	V486M	486	Missense	distal	6	no	3.358	3.506	EPSD	COSMIC	3.469	Gain
TK_Src_SrcA_FYN_Y	P14923	JUP	P06241	FYN	Y550	G545D	545	Missense	distal	-5	no	3.818	4.606	EPSD;PhosphoSitePlus	COSMIC	3.469	Up-regulation
TK_Src_SrcA_FYN_Y	Q14194	CRMP1	P06241	FYN	Y32	D27Y	27	Missense	distal	-5	no	5.405	4.036	EPSD	COSMIC	3.469	Down-regulation
TK_Src_SrcA_FYN_Y	Q14194	CRMP1	P06241	FYN	Y499	G493V	493	Missense	distal	-6	no	3.530	3.404	EPSD	COSMIC	3.469	Loss
TK_Src_SrcA_FYN_Y	Q14194	CRMP1	P06241	FYN	Y499	E505K	505	Missense	distal	6	no	3.530	3.264	EPSD	COSMIC	3.469	Loss
TK_Src_SrcA_FYN_Y	Q14194	CRMP1	P06241	FYN	Y499	R496S	496	Missense	distal	-3	no	3.530	4.076	EPSD	COSMIC	3.469	Up-regulation
TK_Src_SrcA_FYN_Y	Q14194	CRMP1	P06241	FYN	Y499	E505D	505	Missense	distal	6	no	3.530	3.596	EPSD	COSMIC	3.469	Up-regulation
TK_Src_SrcA_FYN_Y	Q14194	CRMP1	P06241	FYN	Y504	A508G	508	Missense	distal	4	no	6.638	6.528	PhosphoSitePlus	COSMIC	3.469	Down-regulation
TK_Src_SrcA_FYN_Y	Q14194	CRMP1	P06241	FYN	Y504	P510H	510	Missense	distal	6	no	6.638	7.039	PhosphoSitePlus	COSMIC	3.469	Up-regulation
TK_Src_SrcA_FYN_Y	Q14194	CRMP1	P06241	FYN	Y504	E505K	505	Missense	proximal	1	no	6.638	5.227	PhosphoSitePlus	COSMIC	3.469	Down-regulation
TK_Src_SrcA_FYN_Y	Q14194	CRMP1	P06241	FYN	Y504	E505D	505	Missense	proximal	1	no	6.638	7.483	PhosphoSitePlus	COSMIC	3.469	Up-regulation
TK_Src_SrcA_FYN_Y	Q16236	NFE2L2	P06241	FYN	Y576	E571K	571	Missense	distal	-5	no	5.519	5.669	PhosphoSitePlus	COSMIC	3.469	Up-regulation
TK_Src_SrcA_FYN_Y	Q16236	NFE2L2	P06241	FYN	Y576	R569C	569	Missense	distal	-7	no	5.519	4.692	PhosphoSitePlus	COSMIC	3.469	Down-regulation
TK_Src_SrcA_FYN_Y	Q16236	NFE2L2	P06241	FYN	Y576	E580K	580	Missense	distal	4	no	5.519	5.743	PhosphoSitePlus	COSMIC	3.469	Up-regulation
TK_Src_SrcA_FYN_Y	Q16236	NFE2L2	P06241	FYN	Y576	S577F	577	Missense	proximal	1	no	5.519	3.727	PhosphoSitePlus	COSMIC	3.469	Down-regulation
TK_Src_SrcA_FYN_Y	Q16236	NFE2L2	P06241	FYN	Y576	Y581N	581	Missense	distal	5	no	5.519	5.412	PhosphoSitePlus	COSMIC	3.469	Down-regulation
TK_Src_SrcA_FYN_Y	Q14524	SCN5A	P06241	FYN	Y1494	E1490D	1490	Missense	distal	-4	no	3.435	4.294	PhosphoSitePlus;EPSD	COSMIC	3.469	Gain
TK_Src_SrcA_FYN_Y	Q14524	SCN5A	P06241	FYN	Y1495	E1490D	1490	Missense	distal	-5	no	6.999	7.077	EPSD;PhosphoSitePlus	COSMIC	3.469	Up-regulation
TK_Src_SrcA_FYN_Y	Q14524	SCN5A	P06241	FYN	Y1495	E1490V	1490	Missense	distal	-5	no	6.999	6.734	EPSD;PhosphoSitePlus	COSMIC	3.469	Down-regulation
TK_Src_SrcA_FYN_Y	Q14524	SCN5A	P06241	FYN	Y1495	K1499T	1499	Missense	distal	4	no	6.999	6.719	EPSD;PhosphoSitePlus	COSMIC	3.469	Down-regulation
TK_Src_SrcA_FYN_Y	Q9UIW2	PLXNA1	P06241	FYN	Y159	V163L	163	Missense	distal	4	no	3.743	3.753	EPSD	COSMIC	3.469	Up-regulation
TK_Src_SrcA_FYN_Y	Q9UIW2	PLXNA1	P06241	FYN	Y159	S162C	162	Missense	distal	3	no	3.743	2.869	EPSD	COSMIC	3.469	Loss
TK_Src_SrcA_FYN_Y	Q9UIW2	PLXNA1	P06241	FYN	Y159	R155C	155	Missense	distal	-4	no	3.743	1.834	EPSD	COSMIC	3.469	Loss
TK_Src_SrcA_FYN_Y	Q9UIW2	PLXNA1	P06241	FYN	Y1403	G1399D	1399	Missense	distal	-4	no	3.161	5.517	EPSD	COSMIC	3.469	Gain
TK_Src_SrcA_FYN_Y	Q9UIW2	PLXNA1	P06241	FYN	Y1486	L1488M	1488	Missense	proximal	2	no	3.750	3.794	EPSD	COSMIC	3.469	Up-regulation
TK_Src_SrcA_FYN_Y	Q9UIW2	PLXNA1	P06241	FYN	Y1486	A1484T	1484	Missense	proximal	-2	no	3.750	3.637	EPSD	COSMIC	3.469	Down-regulation
TK_Src_SrcA_FYN_Y	Q9UIW2	PLXNA1	P06241	FYN	Y1486	S1489I	1489	Missense	distal	3	no	3.750	3.954	EPSD	COSMIC	3.469	Up-regulation
TK_Src_SrcA_FYN_Y	Q9UIW2	PLXNA1	P06241	FYN	Y1608	P1602H	1602	Missense	distal	-6	no	4.852	5.207	EPSD;PhosphoSitePlus	COSMIC;CCLE	3.469	Up-regulation
TK_Src_SrcA_FYN_Y	Q9UIW2	PLXNA1	P06241	FYN	Y1679	R1682Q	1682	Missense	distal	3	no	5.272	4.841	PhosphoSitePlus;EPSD	COSMIC	3.469	Down-regulation
TK_Src_SrcA_FYN_Y	P11137	MAP2	P06241	FYN	Y50	P49A	49	Missense	proximal	-1	no	6.379	5.093	EPSD;PhosphoSitePlus	COSMIC;GDSC;CCLE	3.469	Down-regulation
TK_Src_SrcA_FYN_Y	P11137	MAP2	P06241	FYN	Y67	Q64R	64	Missense	distal	-3	no	5.132	4.629	PhosphoSitePlus;EPSD	COSMIC	3.469	Down-regulation
TK_Src_SrcA_FYN_Y	P11137	MAP2	P06241	FYN	Y67	S68L	68	Missense	proximal	1	no	5.132	4.261	PhosphoSitePlus;EPSD	COSMIC	3.469	Down-regulation
TK_Src_SrcA_FYN_Y	P11137	MAP2	P06241	FYN	Y67	G65D	65	Missense	proximal	-2	no	5.132	4.384	PhosphoSitePlus;EPSD	COSMIC	3.469	Down-regulation
TK_Src_SrcA_FYN_Y	P11137	MAP2	P06241	FYN	Y563	M569I	569	Missense	distal	6	no	4.607	4.953	EPSD	COSMIC	3.469	Up-regulation
TK_Src_SrcA_FYN_Y	P11137	MAP2	P06241	FYN	Y592	R599S	599	Missense	distal	7	no	3.930	3.912	EPSD	COSMIC	3.469	Down-regulation
TK_Src_SrcA_FYN_Y	P11137	MAP2	P06241	FYN	Y592	P588T	588	Missense	distal	-4	no	3.930	4.948	EPSD	COSMIC	3.469	Up-regulation
TK_Src_SrcA_FYN_Y	P11137	MAP2	P06241	FYN	Y592	L595M	595	Missense	distal	3	no	3.930	4.044	EPSD	COSMIC	3.469	Up-regulation
TK_Src_SrcA_FYN_Y	P11137	MAP2	P06241	FYN	Y592	S590I	590	Missense	proximal	-2	no	3.930	3.048	EPSD	COSMIC	3.469	Loss
TK_Src_SrcA_FYN_Y	P11137	MAP2	P06241	FYN	Y592	Y593C	593	Missense	proximal	1	no	3.930	1.695	EPSD	COSMIC	3.469	Loss
TK_Src_SrcA_FYN_Y	P11137	MAP2	P06241	FYN	Y592	Y593H	593	Missense	proximal	1	no	3.930	4.289	EPSD	COSMIC	3.469	Up-regulation
TK_Src_SrcA_FYN_Y	P11137	MAP2	P06241	FYN	Y637	Q633H	633	Missense	distal	-4	no	5.182	4.188	EPSD	COSMIC;GDSC;CCLE	3.469	Down-regulation
TK_Src_SrcA_FYN_Y	P11137	MAP2	P06241	FYN	Y637	A641T	641	Missense	distal	4	no	5.182	5.241	EPSD	COSMIC;GDSC;CCLE	3.469	Up-regulation
TK_Src_SrcA_FYN_Y	P11137	MAP2	P06241	FYN	Y644	P645T	645	Missense	proximal	1	no	2.838	3.731	EPSD	COSMIC	3.469	Gain
TK_Src_SrcA_FYN_Y	P11137	MAP2	P06241	FYN	Y745	D743G	743	Missense	proximal	-2	no	2.799	3.548	EPSD	COSMIC	3.469	Gain
TK_Src_SrcA_FYN_Y	P11137	MAP2	P06241	FYN	Y1131	H1137N	1137	Missense	distal	6	no	4.486	4.187	EPSD	COSMIC	3.469	Down-regulation
TK_Src_SrcA_FYN_Y	P11137	MAP2	P06241	FYN	Y1131	D1126Y	1126	Missense	distal	-5	no	4.486	3.117	EPSD	COSMIC	3.469	Loss
TK_Src_SrcA_FYN_Y	P11137	MAP2	P06241	FYN	Y1131	E1138G	1138	Missense	distal	7	no	4.486	4.439	EPSD	COSMIC	3.469	Down-regulation
TK_Src_SrcA_FYN_Y	P11137	MAP2	P06241	FYN	Y1131	A1124S	1124	Missense	distal	-7	no	4.486	4.256	EPSD	COSMIC	3.469	Down-regulation
TK_Src_SrcA_FYN_Y	P51812	RPS6KA3	P06241	FYN	Y144	L145H	145	Missense	proximal	1	no	3.444	4.461	EPSD	COSMIC	3.469	Gain
TK_Src_SrcA_FYN_Y	P51812	RPS6KA3	P06241	FYN	Y483	D481G	481	Missense	proximal	-2	no	4.740	5.488	EPSD;PhosphoSitePlus	COSMIC	3.469	Up-regulation
TK_Src_SrcA_FYN_Y	P51812	RPS6KA3	P06241	FYN	Y483	Y483C	483	Missense	central	0	yes	4.740	0.000	EPSD;PhosphoSitePlus	COSMIC	3.469	Loss
TK_Src_SrcA_FYN_Y	P51812	RPS6KA3	P06241	FYN	Y488	D481G	481	Missense	distal	-7	no	5.626	4.963	EPSD;PhosphoSitePlus	COSMIC	3.469	Down-regulation
TK_Src_SrcA_FYN_Y	P51812	RPS6KA3	P06241	FYN	Y488	Y483C	483	Missense	distal	-5	no	5.626	6.039	EPSD;PhosphoSitePlus	COSMIC	3.469	Up-regulation
TK_Src_SrcA_FYN_Y	P51812	RPS6KA3	P06241	FYN	Y529	G534S	534	Missense	distal	5	no	4.478	4.561	PhosphoSitePlus;EPSD	COSMIC	3.469	Up-regulation
TK_Src_SrcA_FYN_Y	P51812	RPS6KA3	P06241	FYN	Y707	K700N	700	Missense	distal	-7	no	7.301	7.996	EPSD;PhosphoSitePlus	COSMIC	3.469	Up-regulation
TK_Src_SrcA_FYN_Y	O43490	PROM1	P06241	FYN	Y214	T221N	221	Missense	distal	7	no	4.698	4.706	EPSD	COSMIC	3.469	Up-regulation
TK_Src_SrcA_FYN_Y	O43490	PROM1	P06241	FYN	Y828	D830H	830	Missense	proximal	2	no	7.475	6.522	EPSD;PhosphoSitePlus	COSMIC	3.469	Down-regulation
TK_Src_SrcA_FYN_Y	O43490	PROM1	P06241	FYN	Y852	Y852C	852	Missense	central	0	yes	3.848	0.000	PhosphoSitePlus;EPSD	COSMIC	3.469	Loss
TK_Src_SrcA_FYN_Y	P04626	ERBB2	P06241	FYN	Y781	V777E	777	Missense	distal	-4	no	2.547	3.705	EPSD	COSMIC	3.469	Gain
TK_Src_SrcA_FYN_Y	P04626	ERBB2	P06241	FYN	Y877	D880N	880	Missense	distal	3	no	2.842	3.542	PhosphoSitePlus	COSMIC	3.469	Gain
TK_Src_SrcA_FYN_Y	P04626	ERBB2	P06241	FYN	Y1005	D1012N	1012	Missense	distal	7	no	3.867	3.885	EPSD	COSMIC	3.469	Up-regulation
TK_Src_SrcA_FYN_Y	P04626	ERBB2	P06241	FYN	Y1127	D1125E	1125	Missense	proximal	-2	no	3.428	3.721	EPSD	COSMIC;GDSC	3.469	Gain
TK_Src_SrcA_FYN_Y	Q14247	CTTN	P06241	FYN	Y162	R168Q	168	Missense	distal	6	no	3.391	3.581	EPSD	COSMIC	3.469	Gain
TK_Src_SrcA_FYN_Y	Q14247	CTTN	P06241	FYN	Y191	D190N	190	Missense	proximal	-1	no	2.623	3.635	EPSD	COSMIC	3.469	Gain
TK_Src_SrcA_FYN_Y	Q14247	CTTN	P06241	FYN	Y310	G311V	311	Missense	proximal	1	no	3.754	2.238	EPSD	COSMIC	3.469	Loss
TK_Src_SrcA_FYN_Y	Q14247	CTTN	P06241	FYN	Y310	R316W	316	Missense	distal	6	no	3.754	4.285	EPSD	COSMIC	3.469	Up-regulation
TK_Src_SrcA_FYN_Y	Q14247	CTTN	P06241	FYN	Y310	G311E	311	Missense	proximal	1	no	3.754	2.759	EPSD	COSMIC	3.469	Loss
TK_Src_SrcA_FYN_Y	Q14247	CTTN	P06241	FYN	Y446	T440P	440	Missense	distal	-6	no	6.372	5.633	EPSD;PhosphoSitePlus	COSMIC	3.469	Down-regulation
TK_Src_SrcA_FYN_Y	Q14247	CTTN	P06241	FYN	Y446	P442L	442	Missense	distal	-4	no	6.372	6.175	EPSD;PhosphoSitePlus	COSMIC	3.469	Down-regulation
TK_Src_SrcA_FYN_Y	Q14247	CTTN	P06241	FYN	Y446	E441K	441	Missense	distal	-5	no	6.372	6.521	EPSD;PhosphoSitePlus	COSMIC	3.469	Up-regulation
TK_Src_SrcA_FYN_Y	Q14247	CTTN	P06241	FYN	Y446	V445M	445	Missense	proximal	-1	no	6.372	4.935	EPSD;PhosphoSitePlus	COSMIC	3.469	Down-regulation
TK_Src_SrcA_FYN_Y	Q14247	CTTN	P06241	FYN	Y464	A463T	463	Missense	proximal	-1	no	3.140	3.999	EPSD	COSMIC	3.469	Gain
TK_Src_SrcA_FYN_Y	Q14247	CTTN	P06241	FYN	Y470	Y464C	464	Missense	distal	-6	no	4.928	5.142	EPSD;PhosphoSitePlus	COSMIC	3.469	Up-regulation
TK_Src_SrcA_FYN_Y	Q14247	CTTN	P06241	FYN	Y470	A463T	463	Missense	distal	-7	no	4.928	4.982	EPSD;PhosphoSitePlus	COSMIC	3.469	Up-regulation
TK_Src_SrcA_FYN_Y	Q14247	CTTN	P06241	FYN	Y470	P476L	476	Missense	distal	6	no	4.928	5.335	EPSD;PhosphoSitePlus	COSMIC;GDSC;CCLE	3.469	Up-regulation
TK_Src_SrcA_FYN_Y	O75886	STAM2	P06241	FYN	Y291	D293N	293	Missense	proximal	2	no	8.221	8.338	EPSD;PhosphoSitePlus	COSMIC	3.469	Up-regulation
TK_Src_SrcA_FYN_Y	O75886	STAM2	P06241	FYN	Y291	K296E	296	Missense	distal	5	no	8.221	7.954	EPSD;PhosphoSitePlus	COSMIC;CCLE	3.469	Down-regulation
TK_Src_SrcA_FYN_Y	O75886	STAM2	P06241	FYN	Y291	S285P	285	Missense	distal	-6	no	8.221	7.467	EPSD;PhosphoSitePlus	COSMIC	3.469	Down-regulation
TK_Src_SrcA_FYN_Y	O75886	STAM2	P06241	FYN	Y291	K284T	284	Missense	distal	-7	no	8.221	8.833	EPSD;PhosphoSitePlus	COSMIC;GDSC;CCLE	3.469	Up-regulation
TK_Src_SrcA_FYN_Y	P05067	APP	P06241	FYN	Y757	E758K	758	Missense	proximal	1	no	4.433	3.022	PhosphoSitePlus	COSMIC	3.469	Loss
TK_Src_SrcA_FYN_Y	P05067	APP	P06241	FYN	Y757	K763R	763	Missense	distal	6	no	4.433	4.636	PhosphoSitePlus	COSMIC	3.469	Up-regulation
TK_Src_SrcA_FYN_Y	P05067	APP	P06241	FYN	Y757	K763E	763	Missense	distal	6	no	4.433	4.700	PhosphoSitePlus	COSMIC	3.469	Up-regulation
TK_Src_SrcA_FYN_Y	P05067	APP	P06241	FYN	Y757	G756S	756	Missense	proximal	-1	no	4.433	3.939	PhosphoSitePlus	COSMIC	3.469	Down-regulation
TK_Src_SrcA_FYN_Y	P05067	APP	P06241	FYN	Y762	K763E	763	Missense	proximal	1	no	2.333	3.744	EPSD	COSMIC	3.469	Gain
TK_Src_SrcA_FYN_Y	O43294	TGFB1I1	P06241	FYN	Y38	P35S	35	Missense	distal	-3	no	2.963	3.521	EPSD	COSMIC	3.469	Gain
TK_Src_SrcA_FYN_Y	O43294	TGFB1I1	P06241	FYN	Y60	R67Q	67	Missense	distal	7	no	6.344	6.320	PhosphoSitePlus	COSMIC	3.469	Down-regulation
TK_Src_SrcA_FYN_Y	P06241	FYN	P06241	FYN	Y28	T35I	35	Missense	distal	7	no	4.699	4.654	EPSD;PhosphoSitePlus	COSMIC	3.469	Down-regulation
TK_Src_SrcA_FYN_Y	P06241	FYN	P06241	FYN	Y28	N23D	23	Missense	distal	-5	no	4.699	5.081	EPSD;PhosphoSitePlus	COSMIC	3.469	Up-regulation
TK_Src_SrcA_FYN_Y	P06241	FYN	P06241	FYN	Y28	P34A	34	Missense	distal	6	no	4.699	4.743	EPSD;PhosphoSitePlus	COSMIC	3.469	Up-regulation
TK_Src_SrcA_FYN_Y	P06241	FYN	P06241	FYN	Y28	P34L	34	Missense	distal	6	no	4.699	5.105	EPSD;PhosphoSitePlus	COSMIC	3.469	Up-regulation
TK_Src_SrcA_FYN_Y	P06241	FYN	P06241	FYN	Y28	R29C	29	Missense	proximal	1	no	4.699	3.256	EPSD;PhosphoSitePlus	COSMIC	3.469	Loss
TK_Src_SrcA_FYN_Y	P06241	FYN	P06241	FYN	Y185	S186L	186	Missense	proximal	1	no	6.198	5.327	EPSD;PhosphoSitePlus	COSMIC	3.469	Down-regulation
TK_Src_SrcA_FYN_Y	P06241	FYN	P06241	FYN	Y185	W192L	192	Missense	distal	7	no	6.198	6.248	EPSD;PhosphoSitePlus	COSMIC	3.469	Up-regulation
TK_Src_SrcA_FYN_Y	P06241	FYN	P06241	FYN	Y185	R190S	190	Missense	distal	5	no	6.198	6.023	EPSD;PhosphoSitePlus	COSMIC	3.469	Down-regulation
TK_Src_SrcA_FYN_Y	P06241	FYN	P06241	FYN	Y185	D191Y	191	Missense	distal	6	no	6.198	6.365	EPSD;PhosphoSitePlus	COSMIC	3.469	Up-regulation
TK_Src_SrcA_FYN_Y	P06241	FYN	P06241	FYN	Y185	K182N	182	Missense	distal	-3	no	6.198	6.877	EPSD;PhosphoSitePlus	COSMIC	3.469	Up-regulation
TK_Src_SrcA_FYN_Y	P06241	FYN	P06241	FYN	Y339	I338M	338	Missense	proximal	-1	no	3.788	3.017	EPSD	COSMIC	3.469	Loss
TK_Src_SrcA_FYN_Y	P06241	FYN	P06241	FYN	Y339	P337T	337	Missense	proximal	-2	no	3.788	4.024	EPSD	COSMIC	3.469	Up-regulation
TK_Src_SrcA_FYN_Y	P06241	FYN	P06241	FYN	Y339	E335K	335	Missense	distal	-4	no	3.788	3.018	EPSD	COSMIC	3.469	Loss
TK_Src_SrcA_FYN_Y	P06241	FYN	P06241	FYN	Y339	E335Q	335	Missense	distal	-4	no	3.788	3.819	EPSD	COSMIC	3.469	Up-regulation
TK_Src_SrcA_FYN_Y	P06241	FYN	P06241	FYN	Y420	R413Q	413	Missense	distal	-7	no	8.640	8.383	EPSD;PhosphoSitePlus	COSMIC	3.469	Down-regulation
TK_Src_SrcA_FYN_Y	Q13291	SLAMF1	P06241	FYN	Y281	A282T	282	Missense	proximal	1	no	4.588	5.116	PhosphoSitePlus;EPSD	COSMIC	3.469	Up-regulation
TK_Src_SrcA_FYN_Y	Q13291	SLAMF1	P06241	FYN	Y281	T279K	279	Missense	proximal	-2	no	4.588	3.658	PhosphoSitePlus;EPSD	COSMIC	3.469	Down-regulation
TK_Src_SrcA_FYN_Y	Q99490	AGAP2	P06241	FYN	Y608	P613Q	613	Missense	distal	5	no	3.013	3.503	EPSD	COSMIC	3.469	Gain
TK_Src_SrcA_FYN_Y	Q99490	AGAP2	P06241	FYN	Y1038	Q1040L	1040	Missense	proximal	2	no	4.198	4.066	EPSD	COSMIC	3.469	Down-regulation
TK_Src_SrcA_FYN_Y	P52209	PGD	P06241	FYN	Y106	G101R	101	Missense	distal	-5	no	3.563	3.958	EPSD	COSMIC;GDSC;CCLE	3.469	Up-regulation
TK_Src_SrcA_FYN_Y	P52209	PGD	P06241	FYN	Y106	R107M	107	Missense	proximal	1	no	3.563	2.726	EPSD	COSMIC	3.469	Loss
TK_Src_SrcA_FYN_Y	Q16539	MAPK14	P06241	FYN	Y35	Y35H	35	Missense	central	0	yes	4.318	0.000	EPSD	COSMIC	3.469	Loss
TK_Src_SrcA_FYN_Y	Q16539	MAPK14	P06241	FYN	Y35	G36N	36	Missense	proximal	1	no	4.318	3.297	EPSD	COSMIC	3.469	Loss
TK_Src_SrcA_FYN_Y	Q16539	MAPK14	P06241	FYN	Y35	A34T	34	Missense	proximal	-1	no	4.318	5.176	EPSD	COSMIC	3.469	Up-regulation
TK_Src_SrcA_FYN_Y	Q16539	MAPK14	P06241	FYN	Y35	G33A	33	Missense	proximal	-2	no	4.318	4.275	EPSD	COSMIC	3.469	Down-regulation
TK_Src_SrcA_FYN_Y	Q16539	MAPK14	P06241	FYN	Y140	L135H	135	Missense	distal	-5	no	3.750	3.855	EPSD	COSMIC	3.469	Up-regulation
TK_Src_SrcA_FYN_Y	Q16539	MAPK14	P06241	FYN	Y140	R136Q	136	Missense	distal	-4	no	3.750	4.469	EPSD	COSMIC	3.469	Up-regulation
TK_Src_SrcA_FYN_Y	Q16539	MAPK14	P06241	FYN	Y323	P322R	322	Missense	proximal	-1	no	4.394	1.738	PhosphoSitePlus	COSMIC;CCLE	3.469	Loss
TK_Src_SrcA_FYN_Y	Q16539	MAPK14	P06241	FYN	Y323	V319L	319	Missense	distal	-4	no	4.394	4.136	PhosphoSitePlus	COSMIC	3.469	Down-regulation
TK_Src_SrcA_FYN_Y	Q8TDQ1	CD300LF	P06241	FYN	Y236	Y236C	236	Missense	central	0	yes	5.493	0.000	EPSD;PhosphoSitePlus	COSMIC	3.469	Loss
TK_Src_SrcA_FYN_Y	Q8TDQ1	CD300LF	P06241	FYN	Y236	A240V	240	Missense	distal	4	no	5.493	5.443	EPSD;PhosphoSitePlus	COSMIC	3.469	Down-regulation
TK_Src_SrcA_FYN_Y	Q8TDQ1	CD300LF	P06241	FYN	Y236	S241F	241	Missense	distal	5	no	5.493	5.395	EPSD;PhosphoSitePlus	COSMIC	3.469	Down-regulation
TK_Src_SrcA_FYN_Y	Q8TDQ1	CD300LF	P06241	FYN	Y263	E257V	257	Missense	distal	-6	no	3.519	3.144	PhosphoSitePlus;EPSD	COSMIC	3.469	Loss
TK_Src_SrcA_FYN_Y	Q8TDQ1	CD300LF	P06241	FYN	Y263	E260K	260	Missense	distal	-3	no	3.519	2.734	PhosphoSitePlus;EPSD	COSMIC	3.469	Loss
TK_Src_SrcA_FYN_Y	Q8TDQ1	CD300LF	P06241	FYN	Y263	E260V	260	Missense	distal	-3	no	3.519	2.029	PhosphoSitePlus;EPSD	COSMIC	3.469	Loss
TK_Src_SrcA_FYN_Y	Q8TDQ1	CD300LF	P06241	FYN	Y263	L269S	269	Missense	distal	6	no	3.519	3.075	PhosphoSitePlus;EPSD	COSMIC	3.469	Loss
TK_Src_SrcA_FYN_Y	O75955	FLOT1	P06241	FYN	Y160	Q158K	158	Missense	proximal	-2	no	4.054	3.620	PhosphoSitePlus	COSMIC	3.469	Down-regulation
TK_Src_SrcA_FYN_Y	O75955	FLOT1	P06241	FYN	Y160	D156N	156	Missense	distal	-4	no	4.054	2.776	PhosphoSitePlus	COSMIC	3.469	Loss
TK_Src_SrcA_FYN_Y	O75955	FLOT1	P06241	FYN	Y223	A222T	222	Missense	proximal	-1	no	4.117	4.976	EPSD	COSMIC	3.469	Up-regulation
TK_Src_SrcA_FYN_Y	O75955	FLOT1	P06241	FYN	Y223	E226K	226	Missense	distal	3	no	4.117	3.610	EPSD	COSMIC	3.469	Down-regulation
TK_Src_SrcA_FYN_Y	Q15858	SCN9A	P06241	FYN	Y1481	N1483H	1483	Missense	proximal	2	no	4.099	3.029	EPSD;PhosphoSitePlus	COSMIC	3.469	Loss
TK_Src_SrcA_FYN_Y	Q15858	SCN9A	P06241	FYN	Y1481	K1480E	1480	Missense	proximal	-1	no	4.099	5.180	EPSD;PhosphoSitePlus	COSMIC	3.469	Up-regulation
TK_Src_SrcA_FYN_Y	Q15858	SCN9A	P06241	FYN	Y1482	N1483H	1483	Missense	proximal	1	no	7.833	8.242	PhosphoSitePlus;EPSD	COSMIC	3.469	Up-regulation
TK_Src_SrcA_FYN_Y	Q15858	SCN9A	P06241	FYN	Y1482	K1480E	1480	Missense	proximal	-2	no	7.833	8.464	PhosphoSitePlus;EPSD	COSMIC	3.469	Up-regulation
TK_Src_SrcA_FYN_Y	P22681	CBL	P06241	FYN	Y371	Y368N	368	Missense	distal	-3	no	2.867	3.481	EPSD	COSMIC	3.469	Gain
TK_Src_SrcA_FYN_Y	P22681	CBL	P06241	FYN	Y552	S558F	558	Missense	distal	6	no	3.362	3.614	EPSD	COSMIC	3.469	Gain
TK_Src_SrcA_FYN_Y	P22681	CBL	P06241	FYN	Y674	A677V	677	Missense	distal	3	no	2.529	3.960	EPSD	COSMIC	3.469	Gain
TK_Src_SrcA_FYN_Y	P22681	CBL	P06241	FYN	Y700	G694D	694	Missense	distal	-6	no	6.283	7.148	PhosphoSitePlus;EPSD	COSMIC	3.469	Up-regulation
TK_Src_SrcA_FYN_Y	P22681	CBL	P06241	FYN	Y700	M701V	701	Missense	proximal	1	no	6.283	7.369	PhosphoSitePlus;EPSD	COSMIC	3.469	Up-regulation
TK_Src_SrcA_FYN_Y	P22681	CBL	P06241	FYN	Y700	P703L	703	Missense	distal	3	no	6.283	5.750	PhosphoSitePlus;EPSD	COSMIC	3.469	Down-regulation
TK_Src_SrcA_FYN_Y	P22681	CBL	P06241	FYN	Y700	S704C	704	Missense	distal	4	no	6.283	6.117	PhosphoSitePlus;EPSD	COSMIC	3.469	Down-regulation
TK_Src_SrcA_FYN_Y	P22681	CBL	P06241	FYN	Y700	P707L	707	Missense	distal	7	no	6.283	6.254	PhosphoSitePlus;EPSD	COSMIC	3.469	Down-regulation
TK_Src_SrcA_FYN_Y	P22681	CBL	P06241	FYN	Y700	S705C	705	Missense	distal	5	no	6.283	5.949	PhosphoSitePlus;EPSD	COSMIC	3.469	Down-regulation
TK_Src_SrcA_FYN_Y	P22681	CBL	P06241	FYN	Y700	R706T	706	Missense	distal	6	no	6.283	6.106	PhosphoSitePlus;EPSD	COSMIC	3.469	Down-regulation
TK_Src_SrcA_FYN_Y	P22681	CBL	P06241	FYN	Y731	S728N	728	Missense	distal	-3	no	3.399	4.158	EPSD;PhosphoSitePlus	COSMIC	3.469	Gain
TK_Src_SrcA_FYN_Y	Q12913	PTPRJ	P06241	FYN	Y587	L593F	593	Missense	distal	6	no	5.344	5.152	EPSD	COSMIC	3.469	Down-regulation
TK_Src_SrcA_FYN_Y	Q12913	PTPRJ	P06241	FYN	Y587	S581A	581	Missense	distal	-6	no	5.344	4.764	EPSD	COSMIC	3.469	Down-regulation
TK_Src_SrcA_FYN_Y	Q12913	PTPRJ	P06241	FYN	Y587	T592I	592	Missense	distal	5	no	5.344	5.114	EPSD	COSMIC	3.469	Down-regulation
TK_Src_SrcA_FYN_Y	Q12913	PTPRJ	P06241	FYN	Y587	L593V	593	Missense	distal	6	no	5.344	4.957	EPSD	COSMIC	3.469	Down-regulation
TK_Src_SrcA_FYN_Y	Q12913	PTPRJ	P06241	FYN	Y1311	S1305L	1305	Missense	distal	-6	no	7.089	6.532	EPSD;PhosphoSitePlus	COSMIC;GDSC;CCLE	3.469	Down-regulation
TK_Src_SrcA_FYN_Y	Q12913	PTPRJ	P06241	FYN	Y1311	A1316T	1316	Missense	distal	5	no	7.089	6.412	EPSD;PhosphoSitePlus	COSMIC	3.469	Down-regulation
TK_Src_SrcA_FYN_Y	Q12913	PTPRJ	P06241	FYN	Y1311	L1309F	1309	Missense	proximal	-2	no	7.089	7.327	EPSD;PhosphoSitePlus	COSMIC	3.469	Up-regulation
TK_Src_SrcA_FYN_Y	Q12913	PTPRJ	P06241	FYN	Y1320	Y1320S	1320	Missense	central	0	yes	4.307	0.000	PhosphoSitePlus;EPSD	COSMIC	3.469	Loss
TK_Src_SrcA_FYN_Y	Q12913	PTPRJ	P06241	FYN	Y1320	T1327I	1327	Missense	distal	7	no	4.307	4.263	PhosphoSitePlus;EPSD	COSMIC	3.469	Down-regulation
TK_Src_SrcA_FYN_Y	Q12913	PTPRJ	P06241	FYN	Y1320	A1324E	1324	Missense	distal	4	no	4.307	4.422	PhosphoSitePlus;EPSD	COSMIC	3.469	Up-regulation
TK_Src_SrcA_FYN_Y	Q12913	PTPRJ	P06241	FYN	Y1320	V1326M	1326	Missense	distal	6	no	4.307	4.454	PhosphoSitePlus;EPSD	COSMIC	3.469	Up-regulation
TK_Src_SrcA_FYN_Y	Q12913	PTPRJ	P06241	FYN	Y1320	A1316T	1316	Missense	distal	-4	no	4.307	5.422	PhosphoSitePlus;EPSD	COSMIC	3.469	Up-regulation
TK_Src_SrcA_FYN_Y	Q14254	FLOT2	P06241	FYN	Y158	S165G	165	Missense	distal	7	no	4.732	4.730	EPSD	COSMIC	3.469	Down-regulation
TK_Src_SrcA_FYN_Y	Q14254	FLOT2	P06241	FYN	Y158	I154M	154	Missense	distal	-4	no	4.732	5.789	EPSD	COSMIC	3.469	Up-regulation
TK_Src_SrcA_FYN_Y	Q14254	FLOT2	P06241	FYN	Y163	S165G	165	Missense	proximal	2	no	4.194	4.528	PhosphoSitePlus	COSMIC	3.469	Up-regulation
TK_Src_SrcA_FYN_Y	Q14254	FLOT2	P06241	FYN	Y163	K169T	169	Missense	distal	6	no	4.194	4.220	PhosphoSitePlus	COSMIC	3.469	Up-regulation
TK_Src_SrcA_FYN_Y	Q14254	FLOT2	P06241	FYN	Y348	A347V	347	Missense	proximal	-1	no	0.898	3.574	EPSD	COSMIC	3.469	Gain
TK_Src_SrcA_FYN_Y	Q96LC7	SIGLEC10	P06241	FYN	Y597	T593M	593	Missense	distal	-4	no	4.679	4.564	EPSD	COSMIC	3.469	Down-regulation
TK_Src_SrcA_FYN_Y	Q96LC7	SIGLEC10	P06241	FYN	Y597	R590Q	590	Missense	distal	-7	no	4.679	4.423	EPSD	COSMIC	3.469	Down-regulation
TK_Src_SrcA_FYN_Y	Q96LC7	SIGLEC10	P06241	FYN	Y597	I598N	598	Missense	proximal	1	no	4.679	5.270	EPSD	COSMIC	3.469	Up-regulation
TK_Src_SrcA_FYN_Y	Q96LC7	SIGLEC10	P06241	FYN	Y597	N599K	599	Missense	proximal	2	no	4.679	4.138	EPSD	COSMIC	3.469	Down-regulation
TK_Src_SrcA_FYN_Y	Q96LC7	SIGLEC10	P06241	FYN	Y597	Y597C	597	Missense	central	0	yes	4.679	0.000	EPSD	COSMIC	3.469	Loss
TK_Src_SrcA_FYN_Y	Q96LC7	SIGLEC10	P06241	FYN	Y667	S661I	661	Missense	distal	-6	no	5.227	4.212	PhosphoSitePlus	COSMIC	3.469	Down-regulation
TK_Src_SrcA_FYN_Y	Q96LC7	SIGLEC10	P06241	FYN	Y691	G686D	686	Missense	distal	-5	no	4.595	5.383	EPSD	COSMIC	3.469	Up-regulation
TK_Src_SrcA_FYN_Y	Q96LC7	SIGLEC10	P06241	FYN	Y691	Q688R	688	Missense	distal	-3	no	4.595	4.093	EPSD	COSMIC	3.469	Down-regulation
TK_Src_SrcA_FYN_Y	Q96LC7	SIGLEC10	P06241	FYN	Y691	Q688H	688	Missense	distal	-3	no	4.595	4.470	EPSD	COSMIC	3.469	Down-regulation
TK_Src_SrcA_FYN_Y	P49023	PXN	P06241	FYN	Y88	S83N	83	Missense	distal	-5	no	4.882	5.280	EPSD	COSMIC	3.469	Up-regulation
TK_Src_SrcA_FYN_Y	P49023	PXN	P06241	FYN	Y118	F120S	120	Missense	proximal	2	no	6.888	6.936	PhosphoSitePlus	COSMIC	3.469	Up-regulation
TK_Src_SrcA_FYN_Y	P49023	PXN	P06241	FYN	Y181	G175W	175	Missense	distal	-6	no	4.438	2.877	EPSD	COSMIC	3.469	Loss
TK_Src_SrcA_FYN_Y	P37840	SNCA	P06241	FYN	Y39	E35D	35	Missense	distal	-4	no	5.433	6.292	EPSD	COSMIC	3.469	Up-regulation
TK_Src_SrcA_FYN_Y	P37840	SNCA	P06241	FYN	Y39	S42Y	42	Missense	distal	3	no	5.433	4.614	EPSD	COSMIC	3.469	Down-regulation
TK_Src_SrcA_FYN_Y	P37840	SNCA	P06241	FYN	Y125	A124S	124	Missense	proximal	-1	no	5.616	5.231	PhosphoSitePlus	COSMIC	3.469	Down-regulation
TK_Src_SrcA_FYN_Y	P37840	SNCA	P06241	FYN	Y125	E130V	130	Missense	distal	5	no	5.616	5.196	PhosphoSitePlus	COSMIC	3.469	Down-regulation
TK_Src_SrcA_FYN_Y	P37840	SNCA	P06241	FYN	Y125	E130A	130	Missense	distal	5	no	5.616	6.017	PhosphoSitePlus	COSMIC	3.469	Up-regulation
TK_Src_SrcA_FYN_Y	P37840	SNCA	P06241	FYN	Y125	D121Y	121	Missense	distal	-4	no	5.616	1.839	PhosphoSitePlus	COSMIC	3.469	Loss
TK_Src_SrcA_FYN_Y	P37840	SNCA	P06241	FYN	Y125	E123K	123	Missense	proximal	-2	no	5.616	4.986	PhosphoSitePlus	COSMIC	3.469	Down-regulation
TK_Src_SrcA_FYN_Y	P37840	SNCA	P06241	FYN	Y125	D121E	121	Missense	distal	-4	no	5.616	4.757	PhosphoSitePlus	COSMIC	3.469	Down-regulation
TK_Src_SrcA_FYN_Y	P37840	SNCA	P06241	FYN	Y136	E130V	130	Missense	distal	-6	no	3.961	3.586	EPSD	COSMIC	3.469	Down-regulation
TK_Src_SrcA_FYN_Y	P37840	SNCA	P06241	FYN	Y136	D135E	135	Missense	proximal	-1	no	3.961	4.975	EPSD	COSMIC;GDSC;CCLE	3.469	Up-regulation
TK_Src_SrcA_FYN_Y	P37840	SNCA	P06241	FYN	Y136	E130A	130	Missense	distal	-6	no	3.961	3.524	EPSD	COSMIC	3.469	Down-regulation
TK_Src_SrcA_FYN_Y	Q9NPH5	NOX4	P06241	FYN	Y566	F570S	570	Missense	distal	4	no	5.844	6.006	PhosphoSitePlus	COSMIC	3.469	Up-regulation
TK_Src_SrcA_FYN_Y	Q9NPH5	NOX4	P06241	FYN	Y566	N563K	563	Missense	distal	-3	no	5.844	5.165	PhosphoSitePlus	COSMIC	3.469	Down-regulation
TK_Src_SrcA_FYN_Y	O14522	PTPRT	P06241	FYN	Y918	E911K	911	Missense	distal	-7	no	4.062	3.026	EPSD	COSMIC	3.469	Loss
TK_Src_SrcA_FYN_Y	O14522	PTPRT	P06241	FYN	Y918	D925Y	925	Missense	distal	7	no	4.062	4.029	EPSD	COSMIC	3.469	Down-regulation
TK_Src_SrcA_FYN_Y	O14522	PTPRT	P06241	FYN	Y918	R913H	913	Missense	distal	-5	no	4.062	3.498	EPSD	COSMIC	3.469	Down-regulation
TK_Src_SrcA_FYN_Y	O14522	PTPRT	P06241	FYN	Y918	R917Q	917	Missense	proximal	-1	no	4.062	5.162	EPSD	COSMIC;GDSC;CCLE	3.469	Up-regulation
TK_Src_SrcA_FYN_Y	O14522	PTPRT	P06241	FYN	Y918	N914I	914	Missense	distal	-4	no	4.062	3.106	EPSD	COSMIC	3.469	Loss
TK_Src_SrcA_FYN_Y	O14522	PTPRT	P06241	FYN	Y918	E911V	911	Missense	distal	-7	no	4.062	3.358	EPSD	COSMIC	3.469	Loss
TK_Src_SrcA_FYN_Y	O14522	PTPRT	P06241	FYN	Y918	R913C	913	Missense	distal	-5	no	4.062	3.499	EPSD	COSMIC	3.469	Down-regulation
TK_Src_SrcA_FYN_Y	O14522	PTPRT	P06241	FYN	Y918	D925E	925	Missense	distal	7	no	4.062	4.105	EPSD	COSMIC	3.469	Up-regulation
TK_Src_SrcA_FYN_Y	O14522	PTPRT	P06241	FYN	Y918	G919V	919	Missense	proximal	1	no	4.062	2.545	EPSD	COSMIC	3.469	Loss
TK_Src_SrcA_FYN_Y	O14522	PTPRT	P06241	FYN	Y918	K915R	915	Missense	distal	-3	no	4.062	3.436	EPSD	COSMIC	3.469	Loss
TK_Src_SrcA_FYN_Y	O14522	PTPRT	P06241	FYN	Y1008	E1006D	1006	Missense	proximal	-2	no	7.020	6.728	EPSD	COSMIC	3.469	Down-regulation
TK_Src_SrcA_FYN_Y	O14522	PTPRT	P06241	FYN	Y1008	E1006K	1006	Missense	proximal	-2	no	7.020	6.390	EPSD	COSMIC	3.469	Down-regulation
TK_Src_SrcA_FYN_Y	O14522	PTPRT	P06241	FYN	Y1008	D1003N	1003	Missense	distal	-5	no	7.020	6.638	EPSD	COSMIC	3.469	Down-regulation
TK_Src_SrcA_FYN_Y	O14522	PTPRT	P06241	FYN	Y1008	D1003G	1003	Missense	distal	-5	no	7.020	6.233	EPSD	COSMIC	3.469	Down-regulation
TK_Src_SrcA_FYN_Y	O14522	PTPRT	P06241	FYN	Y1008	V1007I	1007	Missense	proximal	-1	no	7.020	6.354	EPSD	COSMIC	3.469	Down-regulation
TK_Src_SrcA_FYN_Y	O14522	PTPRT	P06241	FYN	Y1008	T1005M	1005	Missense	distal	-3	no	7.020	5.888	EPSD	COSMIC;GDSC	3.469	Down-regulation
TK_Src_SrcA_FYN_Y	O14522	PTPRT	P06241	FYN	Y1008	T1014M	1014	Missense	distal	6	no	7.020	7.223	EPSD	COSMIC	3.469	Up-regulation
TK_Src_SrcA_FYN_Y	O14522	PTPRT	P06241	FYN	Y1008	L1015M	1015	Missense	distal	7	no	7.020	7.054	EPSD	COSMIC	3.469	Up-regulation
TK_Src_SrcA_FYN_Y	O14522	PTPRT	P06241	FYN	Y1008	V1007A	1007	Missense	proximal	-1	no	7.020	4.344	EPSD	COSMIC	3.469	Down-regulation
TK_Src_SrcA_FYN_Y	O14522	PTPRT	P06241	FYN	Y1008	V1007L	1007	Missense	proximal	-1	no	7.020	5.326	EPSD	COSMIC	3.469	Down-regulation
TK_Src_SrcA_FYN_Y	O14522	PTPRT	P06241	FYN	Y1008	D1004G	1004	Missense	distal	-4	no	7.020	4.664	EPSD	COSMIC	3.469	Down-regulation
TK_Src_SrcA_FYN_Y	P40763	STAT3	P06241	FYN	Y22	M28I	28	Missense	distal	6	no	3.772	4.118	EPSD	COSMIC	3.469	Up-regulation
TK_Src_SrcA_FYN_Y	P40763	STAT3	P06241	FYN	Y22	L18V	18	Missense	distal	-4	no	3.772	4.030	EPSD	COSMIC	3.469	Up-regulation
TK_Src_SrcA_FYN_Y	P40763	STAT3	P06241	FYN	Y22	P27S	27	Missense	distal	5	no	3.772	3.844	EPSD	COSMIC	3.469	Up-regulation
TK_Src_SrcA_FYN_Y	P40763	STAT3	P06241	FYN	Y22	L18H	18	Missense	distal	-4	no	3.772	4.226	EPSD	COSMIC	3.469	Up-regulation
TK_Src_SrcA_FYN_Y	P40763	STAT3	P06241	FYN	Y22	L18P	18	Missense	distal	-4	no	3.772	3.969	EPSD	COSMIC	3.469	Up-regulation
TK_Src_SrcA_FYN_Y	P40763	STAT3	P06241	FYN	Y446	H447Y	447	Missense	proximal	1	no	4.534	4.176	EPSD	COSMIC	3.469	Down-regulation
TK_Src_SrcA_FYN_Y	P40763	STAT3	P06241	FYN	Y446	I452F	452	Missense	distal	6	no	4.534	4.236	EPSD	COSMIC	3.469	Down-regulation
TK_Src_SrcA_FYN_Y	P40763	STAT3	P06241	FYN	Y640	Q643K	643	Missense	distal	3	no	4.147	3.572	EPSD	COSMIC	3.469	Down-regulation
TK_Src_SrcA_FYN_Y	P40763	STAT3	P06241	FYN	Y640	E638Q	638	Missense	proximal	-2	no	4.147	3.950	EPSD	COSMIC	3.469	Down-regulation
TK_Src_SrcA_FYN_Y	P40763	STAT3	P06241	FYN	Y705	D698N	698	Missense	distal	-7	no	6.980	7.009	PhosphoSitePlus	COSMIC	3.469	Up-regulation
TK_Src_SrcA_FYN_Y	P40763	STAT3	P06241	FYN	Y705	G700R	700	Missense	distal	-5	no	6.980	7.375	PhosphoSitePlus	COSMIC	3.469	Up-regulation
TK_Src_SrcA_FYN_Y	P40763	STAT3	P06241	FYN	Y705	I711L	711	Missense	distal	6	no	6.980	6.873	PhosphoSitePlus	COSMIC	3.469	Down-regulation
TK_Src_SrcA_FYN_Y	P12318	FCGR2A	P06241	FYN	Y281	T277I	277	Missense	distal	-4	no	4.017	2.845	EPSD	COSMIC	3.469	Loss
TK_Src_SrcA_FYN_Y	P12318	FCGR2A	P06241	FYN	Y281	G286D	286	Missense	distal	5	no	4.017	4.096	EPSD	COSMIC	3.469	Up-regulation
TK_Src_SrcA_FYN_Y	P12318	FCGR2A	P06241	FYN	Y281	G286S	286	Missense	distal	5	no	4.017	4.100	EPSD	COSMIC;CCLE	3.469	Up-regulation
TK_Src_SrcA_FYN_Y	P12318	FCGR2A	P06241	FYN	Y304	P309S	309	Missense	distal	5	no	6.199	6.271	EPSD	COSMIC	3.469	Up-regulation
TK_Src_SrcA_FYN_Y	P35637	FUS	P06241	FYN	Y468	G465S	465	Missense	distal	-3	no	5.597	4.907	EPSD	COSMIC	3.469	Down-regulation
TK_Src_SrcA_FYN_Y	P35637	FUS	P06241	FYN	Y468	G475R	475	Missense	distal	7	no	5.597	5.618	EPSD	COSMIC	3.469	Up-regulation
TK_Src_SrcA_FYN_Y	P35637	FUS	P06241	FYN	Y468	R473C	473	Missense	distal	5	no	5.597	5.088	EPSD	COSMIC	3.469	Down-regulation
TK_Src_SrcA_FYN_Y	P35637	FUS	P06241	FYN	Y468	G474R	474	Missense	distal	6	no	5.597	5.659	EPSD	COSMIC	3.469	Up-regulation
TK_Src_SrcA_FYN_Y	P35637	FUS	P06241	FYN	Y468	G469R	469	Missense	proximal	1	no	5.597	3.833	EPSD	COSMIC	3.469	Down-regulation
TK_Src_SrcA_FYN_Y	P35637	FUS	P06241	FYN	Y468	N467K	467	Missense	proximal	-1	no	5.597	4.518	EPSD	COSMIC	3.469	Down-regulation
TK_Src_SrcA_FYN_Y	P35637	FUS	P06241	FYN	Y468	G466S	466	Missense	proximal	-2	no	5.597	5.312	EPSD	COSMIC	3.469	Down-regulation
TK_Src_SrcA_FYN_Y	P35637	FUS	P06241	FYN	Y468	R472C	472	Missense	distal	4	no	5.597	5.513	EPSD	COSMIC	3.469	Down-regulation
TK_Src_SrcA_FYN_Y	P35637	FUS	P06241	FYN	Y468	G461C	461	Missense	distal	-7	no	5.597	5.769	EPSD	COSMIC	3.469	Up-regulation
TK_Src_SrcA_FYN_Y	Q06124	PTPN11	P06241	FYN	Y62	D61H	61	Missense	proximal	-1	no	2.729	3.573	EPSD	COSMIC	3.469	Gain
TK_Src_SrcA_FYN_Y	Q06124	PTPN11	P06241	FYN	Y66	Y62D	62	Missense	distal	-4	no	-0.073	3.705	EPSD	COSMIC	3.469	Gain
TK_Src_SrcA_FYN_Y	Q06124	PTPN11	P06241	FYN	Y304	M311V	311	Missense	distal	7	no	3.867	3.838	EPSD	COSMIC	3.469	Down-regulation
TK_Src_SrcA_FYN_Y	Q06124	PTPN11	P06241	FYN	Y304	I309V	309	Missense	distal	5	no	3.867	3.954	EPSD	COSMIC	3.469	Up-regulation
TK_Src_SrcA_FYN_Y	Q06124	PTPN11	P06241	FYN	Y546	S552F	552	Missense	distal	6	no	7.013	7.265	EPSD	COSMIC	3.469	Up-regulation
TK_Src_SrcA_FYN_Y	Q06124	PTPN11	P06241	FYN	Y546	E545K	545	Missense	proximal	-1	no	7.013	5.932	EPSD	COSMIC	3.469	Down-regulation
TK_Src_SrcA_FYN_Y	Q06124	PTPN11	P06241	FYN	Y546	E545D	545	Missense	proximal	-1	no	7.013	5.999	EPSD	COSMIC	3.469	Down-regulation
TK_Src_SrcA_FYN_Y	Q06124	PTPN11	P06241	FYN	Y546	I549L	549	Missense	distal	3	no	7.013	6.867	EPSD	COSMIC	3.469	Down-regulation
TK_Src_SrcA_FYN_Y	Q06124	PTPN11	P06241	FYN	Y546	Y546C	546	Missense	central	0	yes	7.013	0.000	EPSD	COSMIC	3.469	Loss
TK_Src_SrcA_FYN_Y	Q06124	PTPN11	P06241	FYN	Y546	N548T	548	Missense	proximal	2	no	7.013	6.807	EPSD	COSMIC	3.469	Down-regulation
TK_Src_SrcA_FYN_Y	Q06124	PTPN11	P06241	FYN	Y546	G543E	543	Missense	distal	-3	no	7.013	7.189	EPSD	COSMIC	3.469	Up-regulation
TK_Src_SrcA_FYN_Y	Q06124	PTPN11	P06241	FYN	Y584	D579E	579	Missense	distal	-5	no	4.453	4.376	EPSD	COSMIC	3.469	Down-regulation
TK_Src_SrcA_FYN_Y	Q06124	PTPN11	P06241	FYN	Y584	R582G	582	Missense	proximal	-2	no	4.453	5.570	EPSD	COSMIC	3.469	Up-regulation
TK_Src_SrcA_FYN_Y	Q06124	PTPN11	P06241	FYN	Y584	V583A	583	Missense	proximal	-1	no	4.453	1.777	EPSD	COSMIC	3.469	Loss
TK_Src_SrcA_FYN_Y	Q06124	PTPN11	P06241	FYN	Y584	V587A	587	Missense	distal	3	no	4.453	3.023	EPSD	COSMIC	3.469	Loss
TK_Src_SrcA_FYN_Y	Q06124	PTPN11	P06241	FYN	Y584	S580I	580	Missense	distal	-4	no	4.453	4.115	EPSD	COSMIC	3.469	Down-regulation
TK_Src_SrcA_FYN_Y	Q9NQC3	RTN4	P06241	FYN	Y718	P713L	713	Missense	distal	-5	no	4.748	4.311	EPSD	COSMIC	3.469	Down-regulation
TK_Src_SrcA_FYN_Y	Q9NQC3	RTN4	P06241	FYN	Y840	T837A	837	Missense	distal	-3	no	5.368	4.936	EPSD	COSMIC	3.469	Down-regulation
TK_Src_SrcA_FYN_Y	Q9NQC3	RTN4	P06241	FYN	Y840	D843E	843	Missense	distal	3	no	5.368	5.870	EPSD	COSMIC	3.469	Up-regulation
TK_Src_SrcA_FYN_Y	Q9NQC3	RTN4	P06241	FYN	Y840	L845F	845	Missense	distal	5	no	5.368	5.598	EPSD	COSMIC	3.469	Up-regulation
TK_Src_SrcA_FYN_Y	Q15762	CD226	P06241	FYN	Y249	Q248E	248	Missense	proximal	-1	no	3.241	4.609	EPSD	COSMIC	3.469	Gain
TK_Src_SrcA_FYN_Y	Q15762	CD226	P06241	FYN	Y322	E319D	319	Missense	distal	-3	no	6.779	7.236	PhosphoSitePlus	COSMIC	3.469	Up-regulation
TK_Src_SrcA_FYN_Y	Q15762	CD226	P06241	FYN	Y322	Y325H	325	Missense	distal	3	no	6.779	6.914	PhosphoSitePlus	COSMIC	3.469	Up-regulation
TK_Src_SrcA_FYN_Y	Q9NZA1	CLIC5	P06241	FYN	Y33	E26V	26	Missense	distal	-7	no	7.553	6.848	PhosphoSitePlus	COSMIC;CCLE	3.469	Down-regulation
TK_Src_SrcA_FYN_Y	Q9NZA1	CLIC5	P06241	FYN	Y33	E27Q	27	Missense	distal	-6	no	7.553	7.371	PhosphoSitePlus	COSMIC	3.469	Down-regulation
TK_Src_SrcA_FYN_Y	P35612	ADD2	P06241	FYN	Y31	R33H	33	Missense	proximal	2	no	2.590	3.612	EPSD	COSMIC	3.469	Gain
TK_Src_SrcA_FYN_Y	P35612	ADD2	P06241	FYN	Y377	R378K	378	Missense	proximal	1	no	5.069	4.428	EPSD	COSMIC	3.469	Down-regulation
TK_Src_SrcA_FYN_Y	P35612	ADD2	P06241	FYN	Y489	P492L	492	Missense	distal	3	no	5.617	5.083	PhosphoSitePlus	COSMIC	3.469	Down-regulation
TK_Src_SrcA_FYN_Y	P35612	ADD2	P06241	FYN	Y489	E494K	494	Missense	distal	5	no	5.617	5.884	PhosphoSitePlus	COSMIC	3.469	Up-regulation
TK_Src_SrcA_FYN_Y	P35612	ADD2	P06241	FYN	Y489	E494D	494	Missense	distal	5	no	5.617	5.457	PhosphoSitePlus	COSMIC	3.469	Down-regulation
TK_Src_SrcA_FYN_Y	Q14643	ITPR1	P06241	FYN	Y353	M351V	351	Missense	proximal	-2	no	7.863	8.016	PhosphoSitePlus	COSMIC	3.469	Up-regulation
TK_Src_SrcA_FYN_Y	Q14643	ITPR1	P06241	FYN	Y353	K350T	350	Missense	distal	-3	no	7.863	8.487	PhosphoSitePlus	COSMIC	3.469	Up-regulation
TK_Src_SrcA_FYN_Y	Q14643	ITPR1	P06241	FYN	Y353	S354F	354	Missense	proximal	1	no	7.863	6.071	PhosphoSitePlus	COSMIC	3.469	Down-regulation
TK_Src_SrcA_FYN_Y	Q14643	ITPR1	P06241	FYN	Y353	A347V	347	Missense	distal	-6	no	7.863	7.925	PhosphoSitePlus	COSMIC	3.469	Up-regulation
TK_Src_SrcA_FYN_Y	Q14643	ITPR1	P06241	FYN	Y353	S357F	357	Missense	distal	4	no	7.863	7.701	PhosphoSitePlus	COSMIC	3.469	Down-regulation
TK_Src_SrcA_FYN_Y	Q14643	ITPR1	P06241	FYN	Y353	M351I	351	Missense	proximal	-2	no	7.863	7.565	PhosphoSitePlus	COSMIC	3.469	Down-regulation
TK_Src_SrcA_FYN_Y	Q14643	ITPR1	P06241	FYN	Y353	E360D	360	Missense	distal	7	no	7.863	7.820	PhosphoSitePlus	COSMIC	3.469	Down-regulation
TK_Src_SrcA_FYN_Y	Q14643	ITPR1	P06241	FYN	Y1355	F1354V	1354	Missense	proximal	-1	no	3.220	6.034	EPSD	COSMIC	3.469	Gain
TK_Src_SrcA_FYN_Y	Q14643	ITPR1	P06241	FYN	Y1355	G1348E	1348	Missense	distal	-7	no	3.220	4.253	EPSD	COSMIC	3.469	Gain
TK_Src_SrcA_FYN_Y	Q14643	ITPR1	P06241	FYN	Y1355	S1360Y	1360	Missense	distal	5	no	3.220	3.546	EPSD	COSMIC	3.469	Gain
TK_Src_SrcA_FYN_Y	Q14643	ITPR1	P06241	FYN	Y1401	T1402I	1402	Missense	proximal	1	no	4.728	4.161	EPSD	COSMIC	3.469	Down-regulation
TK_Src_SrcA_FYN_Y	Q14643	ITPR1	P06241	FYN	Y1401	T1395M	1395	Missense	distal	-6	no	4.728	4.108	EPSD	COSMIC	3.469	Down-regulation
TK_Src_SrcA_FYN_Y	Q14643	ITPR1	P06241	FYN	Y1401	G1397D	1397	Missense	distal	-4	no	4.728	7.084	EPSD	COSMIC	3.469	Up-regulation
TK_Src_SrcA_FYN_Y	P10636	MAPT	P06241	FYN	Y18	R23K	23	Missense	distal	5	no	7.108	7.356	PhosphoSitePlus	COSMIC	3.469	Up-regulation
TK_Src_SrcA_FYN_Y	P10636	MAPT	P06241	FYN	Y29	T30S	30	Missense	proximal	1	no	5.368	5.653	EPSD	COSMIC	3.469	Up-regulation
TK_Src_SrcA_FYN_Y	P10636	MAPT	P06241	FYN	Y29	R23K	23	Missense	distal	-6	no	5.368	5.504	EPSD	COSMIC	3.469	Up-regulation
TK_Src_SrcA_FYN_Y	P10636	MAPT	P06241	FYN	Y514	G518V	518	Missense	distal	4	no	3.418	3.479	EPSD	COSMIC	3.469	Gain
TK_Src_SrcA_FYN_Y	P10636	MAPT	P06241	FYN	Y514	G509V	509	Missense	distal	-5	no	3.418	3.863	EPSD	COSMIC	3.469	Gain
TK_Src_SrcA_FYN_Y	P78352	DLG4	P06241	FYN	Y294	R293H	293	Missense	proximal	-1	no	1.275	3.574	EPSD	COSMIC;CCLE	3.469	Gain
TK_Src_SrcA_FYN_Y	P78352	DLG4	P06241	FYN	Y523	R516Q	516	Missense	distal	-7	no	5.978	5.722	PhosphoSitePlus	COSMIC	3.469	Down-regulation
TK_Src_SrcA_FYN_Y	P78352	DLG4	P06241	FYN	Y523	M529I	529	Missense	distal	6	no	5.978	6.324	PhosphoSitePlus	COSMIC	3.469	Up-regulation
TK_Src_SrcA_FYN_Y	P78352	DLG4	P06241	FYN	Y523	T527M	527	Missense	distal	4	no	5.978	6.032	PhosphoSitePlus	COSMIC	3.469	Up-regulation
TK_Src_SrcA_FYN_Y	P78352	DLG4	P06241	FYN	Y523	S519W	519	Missense	distal	-4	no	5.978	3.609	PhosphoSitePlus	COSMIC	3.469	Down-regulation
TK_Src_SrcA_FYN_Y	P78352	DLG4	P06241	FYN	Y523	E524D	524	Missense	proximal	1	no	5.978	6.823	PhosphoSitePlus	COSMIC	3.469	Up-regulation
TK_Src_SrcA_FYN_Y	P78352	DLG4	P06241	FYN	Y580	R578H	578	Missense	proximal	-2	no	5.614	5.668	EPSD	COSMIC;GDSC	3.469	Up-regulation
TK_Src_SrcA_FYN_Y	P78352	DLG4	P06241	FYN	Y580	S585F	585	Missense	distal	5	no	5.614	5.516	EPSD	COSMIC	3.469	Down-regulation
TK_Src_SrcA_FYN_Y	P78352	DLG4	P06241	FYN	Y580	S584L	584	Missense	distal	4	no	5.614	5.509	EPSD	COSMIC	3.469	Down-regulation
TK_Src_SrcA_FYN_Y	P78352	DLG4	P06241	FYN	Y580	R586Q	586	Missense	distal	6	no	5.614	5.804	EPSD	COSMIC	3.469	Up-regulation
TK_Src_SrcA_FYN_Y	P78352	DLG4	P06241	FYN	Y580	R578Q	578	Missense	proximal	-2	no	5.614	6.078	EPSD	COSMIC	3.469	Up-regulation
TK_Src_SrcA_FYN_Y	P78352	DLG4	P06241	FYN	Y580	Y573N	573	Missense	distal	-7	no	5.614	6.720	EPSD	COSMIC	3.469	Up-regulation
TK_Src_SrcA_FYN_Y	P78352	DLG4	P06241	FYN	Y580	D579H	579	Missense	proximal	-1	no	5.614	6.458	EPSD	COSMIC	3.469	Up-regulation
TK_Src_SrcA_FYN_Y	P78352	DLG4	P06241	FYN	Y580	D576H	576	Missense	distal	-4	no	5.614	3.792	EPSD	COSMIC	3.469	Down-regulation
TK_Src_SrcA_FYN_Y	A8K4G0	CD300LB	P06241	FYN	Y188	M189K	189	Missense	proximal	1	no	5.076	5.272	PhosphoSitePlus	COSMIC	3.469	Up-regulation
TK_Src_SrcA_FYN_Y	A8K4G0	CD300LB	P06241	FYN	Y188	G183R	183	Missense	distal	-5	no	5.076	5.471	PhosphoSitePlus	COSMIC	3.469	Up-regulation
TK_Src_SrcA_FYN_Y	A8K4G0	CD300LB	P06241	FYN	Y188	E193K	193	Missense	distal	5	no	5.076	5.342	PhosphoSitePlus	COSMIC	3.469	Up-regulation
TK_Src_SrcA_FYN_Y	A8K4G0	CD300LB	P06241	FYN	Y188	S192F	192	Missense	distal	4	no	5.076	4.914	PhosphoSitePlus	COSMIC	3.469	Down-regulation
TK_Src_SrcA_FYN_Y	A8K4G0	CD300LB	P06241	FYN	Y188	P182T	182	Missense	distal	-6	no	5.076	5.814	PhosphoSitePlus	COSMIC	3.469	Up-regulation
TK_Src_SrcA_FYN_Y	A8K4G0	CD300LB	P06241	FYN	Y188	E184K	184	Missense	distal	-4	no	5.076	4.306	PhosphoSitePlus	COSMIC	3.469	Down-regulation
TK_Src_SrcA_FYN_Y	A8K4G0	CD300LB	P06241	FYN	Y188	G183W	183	Missense	distal	-5	no	5.076	4.380	PhosphoSitePlus	COSMIC	3.469	Down-regulation
TK_Src_SrcA_FYN_Y	A8K4G0	CD300LB	P06241	FYN	Y188	I187M	187	Missense	proximal	-1	no	5.076	4.305	PhosphoSitePlus	COSMIC	3.469	Down-regulation
TK_Src_SrcA_FYN_Y	A8K4G0	CD300LB	P06241	FYN	Y188	E184G	184	Missense	distal	-4	no	5.076	3.579	PhosphoSitePlus	COSMIC	3.469	Down-regulation
TK_Src_SrcA_FYN_Y	P17612	PRKACA	P06241	FYN	Y205	L206R	206	Missense	proximal	1	no	3.662	3.529	EPSD	COSMIC	3.469	Down-regulation
TK_Src_SrcA_FYN_Y	P17612	PRKACA	P06241	FYN	Y205	A207V	207	Missense	proximal	2	no	3.662	3.268	EPSD	COSMIC	3.469	Loss
Other_TTK_TTK_ST	Q9Y5T5	USP16	P33981	TTK	S415	D422N	422	Missense	distal	7	no	24.803	25.410	PhosphoSitePlus;EPSD	COSMIC	18.469	Up-regulation
Other_TTK_TTK_ST	Q9Y5T5	USP16	P33981	TTK	S531	Q529K	529	Missense	proximal	-2	no	19.122	18.444	EPSD	COSMIC	18.469	Loss
Other_TTK_TTK_ST	Q9Y5T5	USP16	P33981	TTK	S531	E533D	533	Missense	proximal	2	no	19.122	18.944	EPSD	COSMIC	18.469	Down-regulation
Other_TTK_TTK_ST	Q9Y5T5	USP16	P33981	TTK	S531	T526I	526	Missense	distal	-5	no	19.122	20.041	EPSD	COSMIC	18.469	Up-regulation
Other_TTK_TTK_ST	Q9Y5T5	USP16	P33981	TTK	S552	P553S	553	Missense	proximal	1	no	22.936	22.948	EPSD;PhosphoSitePlus	COSMIC	18.469	Up-regulation
Other_TTK_TTK_ST	Q9Y5T5	USP16	P33981	TTK	S552	E547Q	547	Missense	distal	-5	no	22.936	21.104	EPSD;PhosphoSitePlus	COSMIC	18.469	Down-regulation
Other_TTK_TTK_ST	Q9Y5T5	USP16	P33981	TTK	T554	P553S	553	Missense	proximal	-1	no	21.399	24.026	EPSD;PhosphoSitePlus	COSMIC	18.469	Up-regulation
Other_TTK_TTK_ST	Q9Y5T5	USP16	P33981	TTK	T554	E547Q	547	Missense	distal	-7	no	21.399	21.193	EPSD;PhosphoSitePlus	COSMIC	18.469	Down-regulation
Other_TTK_TTK_ST	P33981	TTK	P33981	TTK	T12	R9T	9	Missense	distal	-3	no	17.713	18.935	EPSD;PhosphoSitePlus	COSMIC	18.469	Gain
Other_TTK_TTK_ST	P33981	TTK	P33981	TTK	S15	D14N	14	Missense	proximal	-1	no	17.745	18.973	EPSD;PhosphoSitePlus	COSMIC	18.469	Gain
Other_TTK_TTK_ST	P33981	TTK	P33981	TTK	S49	N48S	48	Missense	proximal	-1	no	19.054	18.428	EPSD	COSMIC	18.469	Loss
Other_TTK_TTK_ST	P33981	TTK	P33981	TTK	S49	T46A	46	Missense	distal	-3	no	19.054	16.775	EPSD	COSMIC	18.469	Loss
Other_TTK_TTK_ST	P33981	TTK	P33981	TTK	S80	P78L	78	Missense	proximal	-2	no	24.126	24.421	EPSD;PhosphoSitePlus	COSMIC	18.469	Up-regulation
Other_TTK_TTK_ST	P33981	TTK	P33981	TTK	S80	P78Q	78	Missense	proximal	-2	no	24.126	24.933	EPSD;PhosphoSitePlus	COSMIC	18.469	Up-regulation
Other_TTK_TTK_ST	P33981	TTK	P33981	TTK	T210	V208A	208	Missense	proximal	-2	no	20.797	21.237	EPSD	COSMIC	18.469	Up-regulation
Other_TTK_TTK_ST	P33981	TTK	P33981	TTK	T210	A205T	205	Missense	distal	-5	no	20.797	20.322	EPSD	COSMIC	18.469	Down-regulation
Other_TTK_TTK_ST	P33981	TTK	P33981	TTK	T288	D289Y	289	Missense	proximal	1	no	20.915	20.905	EPSD;PhosphoSitePlus	COSMIC	18.469	Down-regulation
Other_TTK_TTK_ST	P33981	TTK	P33981	TTK	S362	E361K	361	Missense	proximal	-1	no	20.350	21.360	EPSD;PhosphoSitePlus	COSMIC	18.469	Up-regulation
Other_TTK_TTK_ST	P33981	TTK	P33981	TTK	S363	E361K	361	Missense	proximal	-2	no	22.150	21.894	EPSD;PhosphoSitePlus	COSMIC	18.469	Down-regulation
Other_TTK_TTK_ST	P33981	TTK	P33981	TTK	S382	N383S	383	Missense	proximal	1	no	19.034	19.035	EPSD	COSMIC	18.469	Up-regulation
Other_TTK_TTK_ST	P33981	TTK	P33981	TTK	S436	T441I	441	Missense	distal	5	no	22.439	21.511	EPSD;PhosphoSitePlus	COSMIC	18.469	Down-regulation
Other_TTK_TTK_ST	P33981	TTK	P33981	TTK	S582	R587Q	587	Missense	distal	5	no	20.360	19.897	EPSD;PhosphoSitePlus	COSMIC	18.469	Down-regulation
Other_TTK_TTK_ST	P33981	TTK	P33981	TTK	S582	I586V	586	Missense	distal	4	no	20.360	20.290	EPSD;PhosphoSitePlus	COSMIC	18.469	Down-regulation
Other_TTK_TTK_ST	P33981	TTK	P33981	TTK	S582	I586T	586	Missense	distal	4	no	20.360	19.885	EPSD;PhosphoSitePlus	COSMIC	18.469	Down-regulation
Other_TTK_TTK_ST	P33981	TTK	P33981	TTK	S582	L588F	588	Missense	distal	6	no	20.360	18.878	EPSD;PhosphoSitePlus	COSMIC	18.469	Down-regulation
Other_TTK_TTK_ST	P33981	TTK	P33981	TTK	S582	H581Q	581	Missense	proximal	-1	no	20.360	23.002	EPSD;PhosphoSitePlus	COSMIC	18.469	Up-regulation
Other_TTK_TTK_ST	P33981	TTK	P33981	TTK	T675	N669K	669	Missense	distal	-6	no	23.394	23.435	EPSD;PhosphoSitePlus	COSMIC	18.469	Up-regulation
Other_TTK_TTK_ST	P33981	TTK	P33981	TTK	T675	S677R	677	Missense	proximal	2	no	23.394	23.643	EPSD;PhosphoSitePlus	COSMIC	18.469	Up-regulation
Other_TTK_TTK_ST	P33981	TTK	P33981	TTK	T676	N669K	669	Missense	distal	-7	no	22.808	22.653	EPSD;PhosphoSitePlus	COSMIC	18.469	Down-regulation
Other_TTK_TTK_ST	P33981	TTK	P33981	TTK	T676	S677R	677	Missense	proximal	1	no	22.808	22.812	EPSD;PhosphoSitePlus	COSMIC	18.469	Up-regulation
Other_TTK_TTK_ST	P33981	TTK	P33981	TTK	S677	S677R	677	Missense	central	0	yes	22.366	0.000	EPSD;PhosphoSitePlus	COSMIC	18.469	Loss
Other_TTK_TTK_ST	P33981	TTK	P33981	TTK	T686	G685D	685	Missense	proximal	-1	no	28.556	28.902	EPSD;PhosphoSitePlus	COSMIC	18.469	Up-regulation
Other_TTK_TTK_ST	P33981	TTK	P33981	TTK	T686	N688Y	688	Missense	proximal	2	no	28.556	28.150	EPSD;PhosphoSitePlus	COSMIC	18.469	Down-regulation
Other_TTK_TTK_ST	P33981	TTK	P33981	TTK	T686	P691Q	691	Missense	distal	5	no	28.556	26.586	EPSD;PhosphoSitePlus	COSMIC	18.469	Down-regulation
Other_TTK_TTK_ST	P33981	TTK	P33981	TTK	S742	Q735H	735	Missense	distal	-7	no	21.676	21.984	EPSD;PhosphoSitePlus	COSMIC	18.469	Up-regulation
Other_TTK_TTK_ST	P33981	TTK	P33981	TTK	S742	I737T	737	Missense	distal	-5	no	21.676	20.758	EPSD;PhosphoSitePlus	COSMIC	18.469	Down-regulation
Other_TTK_TTK_ST	P33981	TTK	P33981	TTK	S742	D749Y	749	Missense	distal	7	no	21.676	21.607	EPSD;PhosphoSitePlus	COSMIC	18.469	Down-regulation
Other_TTK_TTK_ST	P33981	TTK	P33981	TTK	S742	I737V	737	Missense	distal	-5	no	21.676	20.069	EPSD;PhosphoSitePlus	COSMIC	18.469	Down-regulation
Other_TTK_TTK_ST	P33981	TTK	P33981	TTK	T795	P789S	789	Missense	distal	-6	no	23.945	24.031	EPSD;PhosphoSitePlus	COSMIC	18.469	Up-regulation
Other_TTK_TTK_ST	P33981	TTK	P33981	TTK	T795	P797Q	797	Missense	proximal	2	no	23.945	25.514	EPSD;PhosphoSitePlus	COSMIC	18.469	Up-regulation
Other_TTK_TTK_ST	P33981	TTK	P33981	TTK	T805	Y811C	811	Missense	distal	6	no	21.694	21.177	EPSD;PhosphoSitePlus	COSMIC;GDSC;CCLE	18.469	Down-regulation
Other_TTK_TTK_ST	P33981	TTK	P33981	TTK	T806	L813M	813	Missense	distal	7	no	21.560	21.316	EPSD;PhosphoSitePlus	COSMIC	18.469	Down-regulation
Other_TTK_TTK_ST	P33981	TTK	P33981	TTK	T806	Y811C	811	Missense	distal	5	no	21.560	23.354	EPSD;PhosphoSitePlus	COSMIC;GDSC;CCLE	18.469	Up-regulation
Other_TTK_TTK_ST	P33981	TTK	P33981	TTK	S821	P822S	822	Missense	proximal	1	no	23.140	23.152	EPSD;PhosphoSitePlus	COSMIC	18.469	Up-regulation
Other_TTK_TTK_ST	P33981	TTK	P33981	TTK	S821	A828V	828	Missense	distal	7	no	23.140	22.606	EPSD;PhosphoSitePlus	COSMIC	18.469	Down-regulation
Other_TTK_TTK_ST	P33981	TTK	P33981	TTK	S821	N823H	823	Missense	proximal	2	no	23.140	21.748	EPSD;PhosphoSitePlus	COSMIC	18.469	Down-regulation
Other_TTK_TTK_ST	P33981	TTK	P33981	TTK	S824	P822S	822	Missense	proximal	-2	no	23.867	23.956	EPSD;PhosphoSitePlus	COSMIC	18.469	Up-regulation
Other_TTK_TTK_ST	P33981	TTK	P33981	TTK	S824	A828V	828	Missense	distal	4	no	23.867	23.742	EPSD;PhosphoSitePlus	COSMIC	18.469	Down-regulation
Other_TTK_TTK_ST	P33981	TTK	P33981	TTK	S824	N823H	823	Missense	proximal	-1	no	23.867	21.648	EPSD;PhosphoSitePlus	COSMIC	18.469	Down-regulation
Other_TTK_TTK_ST	P33981	TTK	P33981	TTK	T831	A828V	828	Missense	distal	-3	no	20.126	20.254	EPSD	COSMIC	18.469	Up-regulation
Other_TTK_TTK_ST	P33981	TTK	P33981	TTK	S845	K848R	848	Missense	distal	3	no	20.477	21.458	EPSD;PhosphoSitePlus	COSMIC	18.469	Up-regulation
Other_TTK_TTK_ST	P33981	TTK	P33981	TTK	S845	N843I	843	Missense	proximal	-2	no	20.477	20.376	EPSD;PhosphoSitePlus	COSMIC	18.469	Down-regulation
Other_TTK_TTK_ST	P33981	TTK	P33981	TTK	S845	K852Q	852	Missense	distal	7	no	20.477	20.434	EPSD;PhosphoSitePlus	COSMIC	18.469	Down-regulation
Other_TTK_TTK_ST	P33981	TTK	P33981	TTK	S847	K848R	848	Missense	proximal	1	no	18.845	18.847	EPSD;PhosphoSitePlus	COSMIC	18.469	Up-regulation
Other_TTK_TTK_ST	P33981	TTK	P33981	TTK	S847	K853Q	853	Missense	distal	6	no	18.845	19.195	EPSD;PhosphoSitePlus	COSMIC	18.469	Up-regulation
Other_TTK_TTK_ST	P33981	TTK	P33981	TTK	S847	N843I	843	Missense	distal	-4	no	18.845	18.850	EPSD;PhosphoSitePlus	COSMIC	18.469	Up-regulation
Other_TTK_TTK_ST	P33981	TTK	P33981	TTK	S847	K852Q	852	Missense	distal	5	no	18.845	17.396	EPSD;PhosphoSitePlus	COSMIC	18.469	Loss
Other_TTK_TTK_ST	P07900	HSP90AA1	P33981	TTK	S68	S72T	72	Missense	distal	4	no	18.827	18.372	EPSD	COSMIC	18.469	Loss
Other_TTK_TTK_ST	P07900	HSP90AA1	P33981	TTK	T109	D102G	102	Missense	distal	-7	no	22.269	22.702	EPSD	COSMIC	18.469	Up-regulation
Other_TTK_TTK_ST	P07900	HSP90AA1	P33981	TTK	T293	N300S	300	Missense	distal	7	no	18.642	18.626	EPSD	COSMIC	18.469	Down-regulation
Other_TTK_TTK_ST	P07900	HSP90AA1	P33981	TTK	T305	N300S	300	Missense	distal	-5	no	20.048	18.007	EPSD	COSMIC	18.469	Loss
Other_TTK_TTK_ST	P07900	HSP90AA1	P33981	TTK	S476	S470C	470	Missense	distal	-6	no	19.384	19.484	EPSD	COSMIC;CCLE	18.469	Up-regulation
Other_TTK_TTK_ST	P07900	HSP90AA1	P33981	TTK	S476	C481G	481	Missense	distal	5	no	19.384	21.937	EPSD	COSMIC	18.469	Up-regulation
Other_TTK_TTK_ST	P07900	HSP90AA1	P33981	TTK	S476	G471V	471	Missense	distal	-5	no	19.384	21.834	EPSD	COSMIC	18.469	Up-regulation
Other_TTK_TTK_ST	P07900	HSP90AA1	P33981	TTK	S476	D472N	472	Missense	distal	-4	no	19.384	19.371	EPSD	COSMIC	18.469	Down-regulation
Other_TTK_TTK_ST	P07900	HSP90AA1	P33981	TTK	T540	K534N	534	Missense	distal	-6	no	21.749	21.708	EPSD	COSMIC;CCLE	18.469	Down-regulation
Other_TTK_TTK_ST	P07900	HSP90AA1	P33981	TTK	S595	P596S	596	Missense	proximal	1	no	19.471	19.483	EPSD	COSMIC;CCLE	18.469	Up-regulation
Other_TTK_TTK_ST	P07900	HSP90AA1	P33981	TTK	T624	M628I	628	Missense	distal	4	no	21.880	21.376	EPSD	COSMIC	18.469	Down-regulation
Other_TTK_TTK_ST	P07900	HSP90AA1	P33981	TTK	T624	A630T	630	Missense	distal	6	no	21.880	21.982	EPSD	COSMIC	18.469	Up-regulation
Other_TTK_TTK_ST	Q53HL2	CDCA8	P33981	TTK	S23	R18M	18	Missense	distal	-5	no	17.262	18.750	EPSD	COSMIC	18.469	Gain
Other_TTK_TTK_ST	Q53HL2	CDCA8	P33981	TTK	T88	T94I	94	Missense	distal	6	no	25.265	22.706	EPSD;PhosphoSitePlus	COSMIC	18.469	Down-regulation
Other_TTK_TTK_ST	Q53HL2	CDCA8	P33981	TTK	T88	A82D	82	Missense	distal	-6	no	25.265	25.282	EPSD;PhosphoSitePlus	COSMIC	18.469	Up-regulation
Other_TTK_TTK_ST	Q53HL2	CDCA8	P33981	TTK	T94	T94I	94	Missense	central	0	yes	24.948	0.000	PhosphoSitePlus;EPSD	COSMIC	18.469	Loss
Other_TTK_TTK_ST	Q53HL2	CDCA8	P33981	TTK	T100	T94I	94	Missense	distal	-6	no	20.199	20.361	EPSD	COSMIC	18.469	Up-regulation
Other_TTK_TTK_ST	Q53HL2	CDCA8	P33981	TTK	T169	R163G	163	Missense	distal	-6	no	26.238	26.190	EPSD;PhosphoSitePlus	COSMIC	18.469	Down-regulation
Other_TTK_TTK_ST	Q53HL2	CDCA8	P33981	TTK	T199	R195S	195	Missense	distal	-4	no	18.699	18.724	EPSD	COSMIC;GDSC	18.469	Up-regulation
Other_TTK_TTK_ST	Q53HL2	CDCA8	P33981	TTK	S224	V231L	231	Missense	distal	7	no	18.527	18.855	EPSD	COSMIC	18.469	Up-regulation
Other_TTK_TTK_ST	Q53HL2	CDCA8	P33981	TTK	T230	G236R	236	Missense	distal	6	no	20.157	19.651	EPSD;PhosphoSitePlus	COSMIC	18.469	Down-regulation
Other_TTK_TTK_ST	Q53HL2	CDCA8	P33981	TTK	T230	V231L	231	Missense	proximal	1	no	20.157	20.155	EPSD;PhosphoSitePlus	COSMIC	18.469	Down-regulation
Other_TTK_TTK_ST	Q53HL2	CDCA8	P33981	TTK	S238	G236R	236	Missense	proximal	-2	no	24.657	24.182	EPSD;PhosphoSitePlus	COSMIC	18.469	Down-regulation
Other_TTK_TTK_ST	Q53HL2	CDCA8	P33981	TTK	S238	V231L	231	Missense	distal	-7	no	24.657	22.203	EPSD;PhosphoSitePlus	COSMIC	18.469	Down-regulation
Other_TTK_TTK_ST	P54132	BLM	P33981	TTK	S42	T41A	41	Missense	proximal	-1	no	19.623	16.728	EPSD	COSMIC	18.469	Loss
Other_TTK_TTK_ST	P54132	BLM	P33981	TTK	S42	F35Y	35	Missense	distal	-7	no	19.623	21.289	EPSD	COSMIC	18.469	Up-regulation
Other_TTK_TTK_ST	P54132	BLM	P33981	TTK	S42	F37Y	37	Missense	distal	-5	no	19.623	20.290	EPSD	COSMIC	18.469	Up-regulation
Other_TTK_TTK_ST	P54132	BLM	P33981	TTK	S42	N45S	45	Missense	distal	3	no	19.623	20.563	EPSD	COSMIC	18.469	Up-regulation
Other_TTK_TTK_ST	P54132	BLM	P33981	TTK	S42	S42Y	42	Missense	central	0	yes	19.623	0.000	EPSD	COSMIC	18.469	Loss
Other_TTK_TTK_ST	P54132	BLM	P33981	TTK	S43	T41A	41	Missense	proximal	-2	no	19.360	19.185	EPSD	COSMIC	18.469	Down-regulation
Other_TTK_TTK_ST	P54132	BLM	P33981	TTK	S43	F37Y	37	Missense	distal	-6	no	19.360	19.328	EPSD	COSMIC	18.469	Down-regulation
Other_TTK_TTK_ST	P54132	BLM	P33981	TTK	S43	N45S	45	Missense	proximal	2	no	19.360	18.051	EPSD	COSMIC	18.469	Loss
Other_TTK_TTK_ST	P54132	BLM	P33981	TTK	S43	S42Y	42	Missense	proximal	-1	no	19.360	13.858	EPSD	COSMIC	18.469	Loss
Other_TTK_TTK_ST	P54132	BLM	P33981	TTK	S106	P109L	109	Missense	distal	3	no	13.332	18.543	EPSD	COSMIC	18.469	Gain
Other_TTK_TTK_ST	P54132	BLM	P33981	TTK	T121	V118I	118	Missense	distal	-3	no	19.222	20.374	EPSD	COSMIC	18.469	Up-regulation
Other_TTK_TTK_ST	P54132	BLM	P33981	TTK	T121	P126S	126	Missense	distal	5	no	19.222	18.057	EPSD	COSMIC	18.469	Loss
Other_TTK_TTK_ST	P54132	BLM	P33981	TTK	T121	P115L	115	Missense	distal	-6	no	19.222	19.236	EPSD	COSMIC	18.469	Up-regulation
Other_TTK_TTK_ST	P54132	BLM	P33981	TTK	T121	E117K	117	Missense	distal	-4	no	19.222	19.246	EPSD	COSMIC	18.469	Up-regulation
Other_TTK_TTK_ST	P54132	BLM	P33981	TTK	T125	V118I	118	Missense	distal	-7	no	19.059	16.964	EPSD	COSMIC	18.469	Loss
Other_TTK_TTK_ST	P54132	BLM	P33981	TTK	T125	P126S	126	Missense	proximal	1	no	19.059	19.071	EPSD	COSMIC	18.469	Up-regulation
Other_TTK_TTK_ST	P54132	BLM	P33981	TTK	T125	S131P	131	Missense	distal	6	no	19.059	19.673	EPSD	COSMIC;CCLE	18.469	Up-regulation
Other_TTK_TTK_ST	P54132	BLM	P33981	TTK	S144	S147F	147	Missense	distal	3	no	23.538	19.180	EPSD;PhosphoSitePlus	COSMIC	18.469	Down-regulation
Other_TTK_TTK_ST	P54132	BLM	P33981	TTK	S144	S144L	144	Missense	central	0	yes	23.538	0.000	EPSD;PhosphoSitePlus	COSMIC	18.469	Loss
Other_TTK_TTK_ST	P54132	BLM	P33981	TTK	S144	T150I	150	Missense	distal	6	no	23.538	20.980	EPSD;PhosphoSitePlus	COSMIC	18.469	Down-regulation
Other_TTK_TTK_ST	P54132	BLM	P33981	TTK	S144	I151M	151	Missense	distal	7	no	23.538	23.951	EPSD;PhosphoSitePlus	COSMIC	18.469	Up-regulation
Other_TTK_TTK_ST	P54132	BLM	P33981	TTK	S316	S315Y	315	Missense	proximal	-1	no	19.672	14.170	EPSD	COSMIC	18.469	Loss
Other_TTK_TTK_ST	P54132	BLM	P33981	TTK	S316	C318S	318	Missense	proximal	2	no	19.672	19.946	EPSD	COSMIC;GDSC;CCLE	18.469	Up-regulation
Other_TTK_TTK_ST	P54132	BLM	P33981	TTK	S343	D340N	340	Missense	distal	-3	no	16.530	18.744	EPSD	COSMIC	18.469	Gain
Other_TTK_TTK_ST	P54132	BLM	P33981	TTK	T357	E356K	356	Missense	proximal	-1	no	18.625	19.635	EPSD	COSMIC	18.469	Up-regulation
Other_TTK_TTK_ST	P54132	BLM	P33981	TTK	T357	C361Y	361	Missense	distal	4	no	18.625	18.308	EPSD	COSMIC;CCLE	18.469	Loss
Other_TTK_TTK_ST	P54132	BLM	P33981	TTK	T357	P355L	355	Missense	proximal	-2	no	18.625	18.920	EPSD	COSMIC	18.469	Up-regulation
Other_TTK_TTK_ST	P54132	BLM	P33981	TTK	T357	A363S	363	Missense	distal	6	no	18.625	17.232	EPSD	COSMIC	18.469	Loss
Other_TTK_TTK_ST	P54132	BLM	P33981	TTK	T359	C361Y	361	Missense	proximal	2	no	17.839	19.016	EPSD	COSMIC;CCLE	18.469	Gain
Other_TTK_TTK_ST	P54132	BLM	P33981	TTK	S367	H374Y	374	Missense	distal	7	no	20.330	19.303	EPSD	COSMIC	18.469	Down-regulation
Other_TTK_TTK_ST	P54132	BLM	P33981	TTK	S367	I366T	366	Missense	proximal	-1	no	20.330	22.286	EPSD	COSMIC;GDSC	18.469	Up-regulation
Other_TTK_TTK_ST	P54132	BLM	P33981	TTK	S367	C361Y	361	Missense	distal	-6	no	20.330	20.182	EPSD	COSMIC;CCLE	18.469	Down-regulation
Other_TTK_TTK_ST	P54132	BLM	P33981	TTK	S367	A363S	363	Missense	distal	-4	no	20.330	20.289	EPSD	COSMIC	18.469	Down-regulation
Other_TTK_TTK_ST	P54132	BLM	P33981	TTK	S367	H374D	374	Missense	distal	7	no	20.330	19.373	EPSD	COSMIC	18.469	Down-regulation
Other_TTK_TTK_ST	P54132	BLM	P33981	TTK	S503	R510K	510	Missense	distal	7	no	19.605	18.725	EPSD	COSMIC	18.469	Down-regulation
Other_TTK_TTK_ST	P54132	BLM	P33981	TTK	S503	E507K	507	Missense	distal	4	no	19.605	18.693	EPSD	COSMIC	18.469	Down-regulation
Other_TTK_TTK_ST	P54132	BLM	P33981	TTK	T508	G512E	512	Missense	distal	4	no	16.358	18.772	EPSD	COSMIC	18.469	Gain
Other_TTK_TTK_ST	P54132	BLM	P33981	TTK	S517	R510K	510	Missense	distal	-7	no	19.139	18.536	EPSD	COSMIC	18.469	Down-regulation
Other_TTK_TTK_ST	P54132	BLM	P33981	TTK	S517	G512R	512	Missense	distal	-5	no	19.139	21.632	EPSD	COSMIC	18.469	Up-regulation
Other_TTK_TTK_ST	P54132	BLM	P33981	TTK	S517	G512E	512	Missense	distal	-5	no	19.139	24.107	EPSD	COSMIC	18.469	Up-regulation
Other_TTK_TTK_ST	P54132	BLM	P33981	TTK	T581	S580P	580	Missense	proximal	-1	no	19.411	16.783	EPSD	COSMIC	18.469	Loss
Other_TTK_TTK_ST	P54132	BLM	P33981	TTK	T742	Y736C	736	Missense	distal	-6	no	18.976	19.124	EPSD	COSMIC	18.469	Up-regulation
Other_TTK_TTK_ST	P54132	BLM	P33981	TTK	S823	P822S	822	Missense	proximal	-1	no	16.511	19.139	EPSD	COSMIC	18.469	Gain
Other_TTK_TTK_ST	P54132	BLM	P33981	TTK	T903	S897F	897	Missense	distal	-6	no	19.109	19.092	EPSD	COSMIC	18.469	Down-regulation
Other_TTK_TTK_ST	P54132	BLM	P33981	TTK	T903	R898W	898	Missense	distal	-5	no	19.109	17.573	EPSD	COSMIC	18.469	Loss
Other_TTK_TTK_ST	P54132	BLM	P33981	TTK	T903	M904K	904	Missense	proximal	1	no	19.109	19.134	EPSD	COSMIC	18.469	Up-regulation
Other_TTK_TTK_ST	P54132	BLM	P33981	TTK	T903	C901Y	901	Missense	proximal	-2	no	19.109	18.944	EPSD	COSMIC	18.469	Down-regulation
Other_TTK_TTK_ST	P54132	BLM	P33981	TTK	S1195	D1188V	1188	Missense	distal	-7	no	20.068	22.349	EPSD	COSMIC	18.469	Up-regulation
Other_TTK_TTK_ST	P54132	BLM	P33981	TTK	S1195	T1192I	1192	Missense	distal	-3	no	20.068	19.068	EPSD	COSMIC	18.469	Down-regulation
Other_TTK_TTK_ST	P54132	BLM	P33981	TTK	S1195	V1198M	1198	Missense	distal	3	no	20.068	19.917	EPSD	COSMIC;GDSC	18.469	Down-regulation
Other_TTK_TTK_ST	P54132	BLM	P33981	TTK	S1196	T1192I	1192	Missense	distal	-4	no	18.832	18.786	EPSD	COSMIC	18.469	Down-regulation
Other_TTK_TTK_ST	P54132	BLM	P33981	TTK	S1196	V1198M	1198	Missense	proximal	2	no	18.832	20.122	EPSD	COSMIC;GDSC	18.469	Up-regulation
Other_TTK_TTK_ST	P54132	BLM	P33981	TTK	S1290	Q1283H	1283	Missense	distal	-7	no	21.545	21.853	EPSD;PhosphoSitePlus	COSMIC	18.469	Up-regulation
Other_TTK_TTK_ST	P54132	BLM	P33981	TTK	S1290	S1290L	1290	Missense	central	0	yes	21.545	0.000	EPSD;PhosphoSitePlus	COSMIC	18.469	Loss
Other_TTK_TTK_ST	P54132	BLM	P33981	TTK	S1296	S1302F	1302	Missense	distal	6	no	20.115	19.004	PhosphoSitePlus;EPSD	COSMIC	18.469	Down-regulation
Other_TTK_TTK_ST	P54132	BLM	P33981	TTK	S1296	S1290L	1290	Missense	distal	-6	no	20.115	20.043	PhosphoSitePlus;EPSD	COSMIC	18.469	Down-regulation
Other_TTK_TTK_ST	P54132	BLM	P33981	TTK	S1374	I1367M	1367	Missense	distal	-7	no	19.292	20.434	EPSD	COSMIC;GDSC;CCLE	18.469	Up-regulation
Other_TTK_TTK_ST	P54132	BLM	P33981	TTK	S1374	T1371M	1371	Missense	distal	-3	no	19.292	16.557	EPSD	COSMIC	18.469	Loss
Other_TTK_TTK_ST	P54132	BLM	P33981	TTK	S1374	S1373F	1373	Missense	proximal	-1	no	19.292	16.319	EPSD	COSMIC	18.469	Loss
Other_TTK_TTK_ST	P54132	BLM	P33981	TTK	S1374	S1368Y	1368	Missense	distal	-6	no	19.292	19.244	EPSD	COSMIC	18.469	Down-regulation
Other_TTK_TTK_ST	P54132	BLM	P33981	TTK	S1374	S1380R	1380	Missense	distal	6	no	19.292	19.218	EPSD	COSMIC	18.469	Down-regulation
Other_TTK_TTK_ST	P54132	BLM	P33981	TTK	S1390	K1395I	1395	Missense	distal	5	no	18.823	17.701	EPSD	COSMIC	18.469	Loss
Other_TTK_TTK_ST	P00519	ABL1	P33981	TTK	T79	G76E	76	Missense	distal	-3	no	16.087	18.595	EPSD	COSMIC	18.469	Gain
Other_TTK_TTK_ST	P00519	ABL1	P33981	TTK	T83	G76E	76	Missense	distal	-7	no	19.018	20.051	EPSD	COSMIC	18.469	Up-regulation
Other_TTK_TTK_ST	P00519	ABL1	P33981	TTK	T83	D77E	77	Missense	distal	-6	no	19.018	18.909	EPSD	COSMIC	18.469	Down-regulation
Other_TTK_TTK_ST	P00519	ABL1	P33981	TTK	T83	R89W	89	Missense	distal	6	no	19.018	18.115	EPSD	COSMIC	18.469	Loss
Other_TTK_TTK_ST	P00519	ABL1	P33981	TTK	T117	K124N	124	Missense	distal	7	no	20.666	20.386	EPSD	COSMIC	18.469	Down-regulation
Other_TTK_TTK_ST	P00519	ABL1	P33981	TTK	S190	T194I	194	Missense	distal	4	no	18.257	18.732	EPSD	COSMIC	18.469	Gain
Other_TTK_TTK_ST	P00519	ABL1	P33981	TTK	T224	G227S	227	Missense	distal	3	no	14.288	19.999	EPSD	COSMIC	18.469	Gain
Other_TTK_TTK_ST	P00519	ABL1	P33981	TTK	T267	Y264C	264	Missense	distal	-3	no	17.438	21.031	EPSD	COSMIC	18.469	Gain
Other_TTK_TTK_ST	P00519	ABL1	P33981	TTK	T267	Y264N	264	Missense	distal	-3	no	17.438	23.585	EPSD	COSMIC	18.469	Gain
Other_TTK_TTK_ST	P00519	ABL1	P33981	TTK	T392	A397P	397	Missense	distal	5	no	16.830	18.622	EPSD	COSMIC	18.469	Gain
Other_TTK_TTK_ST	P00519	ABL1	P33981	TTK	T406	F401L	401	Missense	distal	-5	no	17.032	18.860	EPSD	COSMIC	18.469	Gain
Other_TTK_TTK_ST	P00519	ABL1	P33981	TTK	S446	E450G	450	Missense	distal	4	no	19.172	16.758	EPSD	COSMIC	18.469	Loss
Other_TTK_TTK_ST	P00519	ABL1	P33981	TTK	S446	L445M	445	Missense	proximal	-1	no	19.172	18.456	EPSD	COSMIC	18.469	Loss
Other_TTK_TTK_ST	P00519	ABL1	P33981	TTK	S446	E453K	453	Missense	distal	7	no	19.172	18.500	EPSD	COSMIC	18.469	Down-regulation
Other_TTK_TTK_ST	P00519	ABL1	P33981	TTK	S446	E450X	450	Missense	distal	4	no	19.172	18.025	EPSD	COSMIC	18.469	Loss
Other_TTK_TTK_ST	P00519	ABL1	P33981	TTK	S446	E450A	450	Missense	distal	4	no	19.172	18.466	EPSD	COSMIC	18.469	Loss
Other_TTK_TTK_ST	P00519	ABL1	P33981	TTK	S446	P441L	441	Missense	distal	-5	no	19.172	20.696	EPSD	COSMIC;CCLE	18.469	Up-regulation
Other_TTK_TTK_ST	P00519	ABL1	P33981	TTK	S446	E453L	453	Missense	distal	7	no	19.172	18.547	EPSD	COSMIC	18.469	Down-regulation
Other_TTK_TTK_ST	P00519	ABL1	P33981	TTK	S446	E450K	450	Missense	distal	4	no	19.172	18.259	EPSD	COSMIC	18.469	Loss
Other_TTK_TTK_ST	P00519	ABL1	P33981	TTK	S446	E453D	453	Missense	distal	7	no	19.172	17.613	EPSD	COSMIC	18.469	Loss
Other_TTK_TTK_ST	P00519	ABL1	P33981	TTK	S446	S446P	446	Missense	central	0	yes	19.172	0.000	EPSD	COSMIC	18.469	Loss
Other_TTK_TTK_ST	P00519	ABL1	P33981	TTK	S446	D444Y	444	Missense	proximal	-2	no	19.172	18.699	EPSD	COSMIC	18.469	Down-regulation
Other_TTK_TTK_ST	P00519	ABL1	P33981	TTK	S446	E453G	453	Missense	distal	7	no	19.172	17.700	EPSD	COSMIC	18.469	Loss
Other_TTK_TTK_ST	P00519	ABL1	P33981	TTK	S446	E453A	453	Missense	distal	7	no	19.172	18.754	EPSD	COSMIC	18.469	Down-regulation
Other_TTK_TTK_ST	P00519	ABL1	P33981	TTK	T597	P592S	592	Missense	distal	-5	no	20.253	20.969	EPSD	COSMIC	18.469	Up-regulation
Other_TTK_TTK_ST	P00519	ABL1	P33981	TTK	T597	N598D	598	Missense	proximal	1	no	20.253	20.258	EPSD	COSMIC;CCLE	18.469	Up-regulation
Other_TTK_TTK_ST	P00519	ABL1	P33981	TTK	T597	A602T	602	Missense	distal	5	no	20.253	21.328	EPSD	COSMIC	18.469	Up-regulation
Other_TTK_TTK_ST	P00519	ABL1	P33981	TTK	T597	I604N	604	Missense	distal	7	no	20.253	20.581	EPSD	COSMIC	18.469	Up-regulation
Other_TTK_TTK_ST	P00519	ABL1	P33981	TTK	T597	K596R	596	Missense	proximal	-1	no	20.253	17.671	EPSD	COSMIC	18.469	Loss
Other_TTK_TTK_ST	P00519	ABL1	P33981	TTK	S708	G701C	701	Missense	distal	-7	no	18.040	19.112	EPSD	COSMIC	18.469	Gain
Other_TTK_TTK_ST	P00519	ABL1	P33981	TTK	S709	G706V	706	Missense	distal	-3	no	18.557	18.860	EPSD	COSMIC	18.469	Up-regulation
Other_TTK_TTK_ST	P00519	ABL1	P33981	TTK	T735	T729M	729	Missense	distal	-6	no	23.873	23.957	PhosphoSitePlus	COSMIC	18.469	Up-regulation
Other_TTK_TTK_ST	P00519	ABL1	P33981	TTK	T735	R732G	732	Missense	distal	-3	no	23.873	22.640	PhosphoSitePlus	COSMIC	18.469	Down-regulation
Other_TTK_TTK_ST	P00519	ABL1	P33981	TTK	T735	R732S	732	Missense	distal	-3	no	23.873	23.713	PhosphoSitePlus	COSMIC	18.469	Down-regulation
Other_TTK_TTK_ST	P00519	ABL1	P33981	TTK	T735	R738Q	738	Missense	distal	3	no	23.873	22.189	PhosphoSitePlus	COSMIC	18.469	Down-regulation
Other_TTK_TTK_ST	P00519	ABL1	P33981	TTK	T735	R738W	738	Missense	distal	3	no	23.873	15.546	PhosphoSitePlus	COSMIC	18.469	Loss
Other_TTK_TTK_ST	P00519	ABL1	P33981	TTK	S919	P918Q	918	Missense	proximal	-1	no	18.968	22.645	EPSD	COSMIC	18.469	Up-regulation
Other_TTK_TTK_ST	P00519	ABL1	P33981	TTK	S919	G924R	924	Missense	distal	5	no	18.968	15.961	EPSD	COSMIC	18.469	Loss
Other_TTK_TTK_ST	P00519	ABL1	P33981	TTK	S919	G924E	924	Missense	distal	5	no	18.968	15.497	EPSD	COSMIC	18.469	Loss
Other_TTK_TTK_ST	P00519	ABL1	P33981	TTK	S919	S915L	915	Missense	distal	-4	no	18.968	18.964	EPSD	COSMIC	18.469	Down-regulation
Other_TTK_TTK_ST	P00519	ABL1	P33981	TTK	S968	S972L	972	Missense	distal	4	no	19.276	19.193	EPSD	COSMIC	18.469	Down-regulation
Other_TTK_TTK_ST	P00519	ABL1	P33981	TTK	S968	P961Q	961	Missense	distal	-7	no	19.276	21.094	EPSD	COSMIC	18.469	Up-regulation
Other_TTK_TTK_ST	P00519	ABL1	P33981	TTK	T1103	C1100F	1100	Missense	distal	-3	no	19.600	18.839	EPSD	COSMIC	18.469	Down-regulation
Other_TTK_TTK_ST	P00519	ABL1	P33981	TTK	T1103	G1107D	1107	Missense	distal	4	no	19.600	20.723	EPSD	COSMIC	18.469	Up-regulation
Other_TTK_TTK_ST	P00519	ABL1	P33981	TTK	T1103	A1102V	1102	Missense	proximal	-1	no	19.600	19.176	EPSD	COSMIC	18.469	Down-regulation
Other_TTK_TTK_ST	P00519	ABL1	P33981	TTK	T1103	A1102S	1102	Missense	proximal	-1	no	19.600	21.306	EPSD	COSMIC	18.469	Up-regulation
Other_TTK_TTK_ST	P00519	ABL1	P33981	TTK	T1103	P1108S	1108	Missense	distal	5	no	19.600	18.435	EPSD	COSMIC	18.469	Loss
Other_TTK_TTK_ST	P00519	ABL1	P33981	TTK	T1103	A1104T	1104	Missense	proximal	1	no	19.600	19.631	EPSD	COSMIC	18.469	Up-regulation
Other_TTK_TTK_ST	P38646	HSPA9	P33981	TTK	T62	T63I	63	Missense	proximal	1	no	19.274	19.251	PhosphoSitePlus;EPSD	COSMIC	18.469	Down-regulation
Other_TTK_TTK_ST	P38646	HSPA9	P33981	TTK	S65	M70V	70	Missense	distal	5	no	22.920	21.410	EPSD;PhosphoSitePlus	COSMIC	18.469	Down-regulation
Other_TTK_TTK_ST	P38646	HSPA9	P33981	TTK	S65	T63I	63	Missense	proximal	-2	no	22.920	22.881	EPSD;PhosphoSitePlus	COSMIC	18.469	Down-regulation
Other_TTK_TTK_ST	P38646	HSPA9	P33981	TTK	T249	I254V	254	Missense	distal	5	no	19.459	20.413	EPSD	COSMIC	18.469	Up-regulation
Other_TTK_TTK_ST	P38646	HSPA9	P33981	TTK	T249	E256K	256	Missense	distal	7	no	19.459	18.787	EPSD	COSMIC	18.469	Down-regulation
Other_TTK_TTK_ST	P38646	HSPA9	P33981	TTK	S644	E649K	649	Missense	distal	5	no	18.429	19.879	EPSD	COSMIC	18.469	Gain
Other_TTK_TTK_ST	O60566	BUB1B	P33981	TTK	S435	A430S	430	Missense	distal	-5	no	21.185	20.300	EPSD;PhosphoSitePlus	COSMIC	18.469	Down-regulation
Other_TTK_TTK_ST	O60566	BUB1B	P33981	TTK	T474	L480R	480	Missense	distal	6	no	18.988	18.542	EPSD	COSMIC	18.469	Down-regulation
Other_TTK_TTK_ST	O60566	BUB1B	P33981	TTK	T474	E476K	476	Missense	proximal	2	no	18.988	18.723	EPSD	COSMIC	18.469	Down-regulation
Other_TTK_TTK_ST	O60566	BUB1B	P33981	TTK	S543	P548S	548	Missense	distal	5	no	23.191	22.026	EPSD;PhosphoSitePlus	COSMIC	18.469	Down-regulation
Other_TTK_TTK_ST	O60566	BUB1B	P33981	TTK	S543	P545L	545	Missense	proximal	2	no	23.191	23.789	EPSD;PhosphoSitePlus	COSMIC	18.469	Up-regulation
Other_TTK_TTK_ST	O60566	BUB1B	P33981	TTK	S543	E538K	538	Missense	distal	-5	no	23.191	22.002	EPSD;PhosphoSitePlus	COSMIC	18.469	Down-regulation
Other_TTK_TTK_ST	O60566	BUB1B	P33981	TTK	S543	R550Q	550	Missense	distal	7	no	23.191	22.267	EPSD;PhosphoSitePlus	COSMIC	18.469	Down-regulation
Other_TTK_TTK_ST	O60566	BUB1B	P33981	TTK	S670	S670R	670	Missense	central	0	yes	23.965	0.000	EPSD;PhosphoSitePlus	COSMIC	18.469	Loss
Other_TTK_TTK_ST	O60566	BUB1B	P33981	TTK	S670	I672S	672	Missense	proximal	2	no	23.965	23.022	EPSD;PhosphoSitePlus	COSMIC;GDSC;CCLE	18.469	Down-regulation
Other_TTK_TTK_ST	O60566	BUB1B	P33981	TTK	S670	L664F	664	Missense	distal	-6	no	23.965	24.020	EPSD;PhosphoSitePlus	COSMIC	18.469	Up-regulation
Other_TTK_TTK_ST	O60566	BUB1B	P33981	TTK	S670	S670I	670	Missense	central	0	yes	23.965	0.000	EPSD;PhosphoSitePlus	COSMIC;GDSC	18.469	Loss
Other_TTK_TTK_ST	O60566	BUB1B	P33981	TTK	S720	P717S	717	Missense	distal	-3	no	16.668	18.480	EPSD	COSMIC	18.469	Gain
Other_TTK_TTK_ST	Q9Y6D9	MAD1L1	P33981	TTK	T13	S12F	12	Missense	proximal	-1	no	19.053	16.080	EPSD	COSMIC	18.469	Loss
Other_TTK_TTK_ST	Q9Y6D9	MAD1L1	P33981	TTK	T13	F20L	20	Missense	distal	7	no	19.053	20.434	EPSD	COSMIC	18.469	Up-regulation
Other_TTK_TTK_ST	Q9Y6D9	MAD1L1	P33981	TTK	S22	F20L	20	Missense	proximal	-2	no	23.151	23.309	EPSD;PhosphoSitePlus	COSMIC	18.469	Up-regulation
Other_TTK_TTK_ST	Q9Y6D9	MAD1L1	P33981	TTK	S62	R59C	59	Missense	distal	-3	no	22.273	20.987	EPSD;PhosphoSitePlus	COSMIC;GDSC	18.469	Down-regulation
Other_TTK_TTK_ST	Q9Y6D9	MAD1L1	P33981	TTK	S62	R59G	59	Missense	distal	-3	no	22.273	21.040	EPSD;PhosphoSitePlus	COSMIC	18.469	Down-regulation
Other_TTK_TTK_ST	Q9Y6D9	MAD1L1	P33981	TTK	S142	R144M	144	Missense	proximal	2	no	18.903	19.988	EPSD	COSMIC	18.469	Up-regulation
Other_TTK_TTK_ST	Q9Y6D9	MAD1L1	P33981	TTK	S142	K143N	143	Missense	proximal	1	no	18.903	18.899	EPSD	COSMIC	18.469	Down-regulation
Other_TTK_TTK_ST	Q9Y6D9	MAD1L1	P33981	TTK	S172	D175H	175	Missense	distal	3	no	18.149	21.226	EPSD	COSMIC	18.469	Gain
Other_TTK_TTK_ST	Q9Y6D9	MAD1L1	P33981	TTK	T323	G325D	325	Missense	proximal	2	no	23.180	24.318	EPSD;PhosphoSitePlus	COSMIC	18.469	Up-regulation
Other_TTK_TTK_ST	Q9Y6D9	MAD1L1	P33981	TTK	T323	S327R	327	Missense	distal	4	no	23.180	22.238	EPSD;PhosphoSitePlus	COSMIC	18.469	Down-regulation
Other_TTK_TTK_ST	Q9Y6D9	MAD1L1	P33981	TTK	T323	W317L	317	Missense	distal	-6	no	23.180	23.048	EPSD;PhosphoSitePlus	COSMIC	18.469	Down-regulation
Other_TTK_TTK_ST	Q9Y6D9	MAD1L1	P33981	TTK	T423	Y418H	418	Missense	distal	-5	no	20.190	20.599	EPSD	COSMIC	18.469	Up-regulation
Other_TTK_TTK_ST	Q9Y6D9	MAD1L1	P33981	TTK	T423	D419G	419	Missense	distal	-4	no	20.190	20.138	EPSD	COSMIC	18.469	Down-regulation
Other_TTK_TTK_ST	Q9Y6D9	MAD1L1	P33981	TTK	T423	E421D	421	Missense	proximal	-2	no	20.190	20.070	EPSD	COSMIC	18.469	Down-regulation
Other_TTK_TTK_ST	Q9Y6D9	MAD1L1	P33981	TTK	T423	P424Q	424	Missense	proximal	1	no	20.190	20.189	EPSD	COSMIC	18.469	Down-regulation
Other_TTK_TTK_ST	Q9Y6D9	MAD1L1	P33981	TTK	T423	P424T	424	Missense	proximal	1	no	20.190	20.227	EPSD	COSMIC	18.469	Up-regulation
Other_TTK_TTK_ST	Q9Y6D9	MAD1L1	P33981	TTK	S428	T432M	432	Missense	distal	4	no	19.866	20.845	EPSD	COSMIC	18.469	Up-regulation
Other_TTK_TTK_ST	Q9Y6D9	MAD1L1	P33981	TTK	S428	R433W	433	Missense	distal	5	no	19.866	22.158	EPSD	COSMIC	18.469	Up-regulation
Other_TTK_TTK_ST	Q9Y6D9	MAD1L1	P33981	TTK	S428	E421D	421	Missense	distal	-7	no	19.866	18.400	EPSD	COSMIC	18.469	Loss
Other_TTK_TTK_ST	Q9Y6D9	MAD1L1	P33981	TTK	S428	P424Q	424	Missense	distal	-4	no	19.866	19.986	EPSD	COSMIC	18.469	Up-regulation
Other_TTK_TTK_ST	Q9Y6D9	MAD1L1	P33981	TTK	S428	P424T	424	Missense	distal	-4	no	19.866	19.976	EPSD	COSMIC	18.469	Up-regulation
Other_TTK_TTK_ST	Q9Y6D9	MAD1L1	P33981	TTK	S490	F493L	493	Missense	distal	3	no	14.436	19.800	EPSD	COSMIC	18.469	Gain
Other_TTK_TTK_ST	Q9Y6D9	MAD1L1	P33981	TTK	S551	R558H	558	Missense	distal	7	no	20.587	19.777	EPSD	COSMIC	18.469	Down-regulation
Other_TTK_TTK_ST	Q9Y6D9	MAD1L1	P33981	TTK	S598	A602T	602	Missense	distal	4	no	24.502	23.971	PhosphoSitePlus;EPSD	COSMIC	18.469	Down-regulation
Other_TTK_TTK_ST	Q9Y6D9	MAD1L1	P33981	TTK	S610	R617Q	617	Missense	distal	7	no	23.425	22.502	EPSD;PhosphoSitePlus	COSMIC;GDSC;CCLE	18.469	Down-regulation
Other_TTK_TTK_ST	Q9Y6D9	MAD1L1	P33981	TTK	S610	Q616L	616	Missense	distal	6	no	23.425	22.573	EPSD;PhosphoSitePlus	COSMIC	18.469	Down-regulation
Other_TTK_TTK_ST	Q9Y6D9	MAD1L1	P33981	TTK	S610	R617W	617	Missense	distal	7	no	23.425	21.507	EPSD;PhosphoSitePlus	COSMIC	18.469	Down-regulation
Other_TTK_TTK_ST	Q9Y6D9	MAD1L1	P33981	TTK	T624	R617Q	617	Missense	distal	-7	no	23.499	23.539	EPSD;PhosphoSitePlus	COSMIC;GDSC;CCLE	18.469	Up-regulation
Other_TTK_TTK_ST	Q9Y6D9	MAD1L1	P33981	TTK	T624	L618R	618	Missense	distal	-6	no	23.499	23.523	EPSD;PhosphoSitePlus	COSMIC	18.469	Up-regulation
Other_TTK_TTK_ST	Q9Y6D9	MAD1L1	P33981	TTK	T624	K619N	619	Missense	distal	-5	no	23.499	24.490	EPSD;PhosphoSitePlus	COSMIC	18.469	Up-regulation
Other_TTK_TTK_ST	Q9Y6D9	MAD1L1	P33981	TTK	T624	R630S	630	Missense	distal	6	no	23.499	23.573	EPSD;PhosphoSitePlus	COSMIC	18.469	Up-regulation
Other_TTK_TTK_ST	Q9Y6D9	MAD1L1	P33981	TTK	T624	R630H	630	Missense	distal	6	no	23.499	22.015	EPSD;PhosphoSitePlus	COSMIC;GDSC;CCLE	18.469	Down-regulation
Other_TTK_TTK_ST	Q9Y6D9	MAD1L1	P33981	TTK	T624	K619E	619	Missense	distal	-5	no	23.499	24.687	EPSD;PhosphoSitePlus	COSMIC	18.469	Up-regulation
Other_TTK_TTK_ST	Q9Y6D9	MAD1L1	P33981	TTK	T624	K625M	625	Missense	proximal	1	no	23.499	23.473	EPSD;PhosphoSitePlus	COSMIC	18.469	Down-regulation
Other_TTK_TTK_ST	Q9Y6D9	MAD1L1	P33981	TTK	T624	R617W	617	Missense	distal	-7	no	23.499	22.091	EPSD;PhosphoSitePlus	COSMIC	18.469	Down-regulation
Other_TTK_TTK_ST	Q96PE2	ARHGEF17	P33981	TTK	S317	G322V	322	Missense	distal	5	no	18.998	16.810	EPSD	COSMIC;GDSC;CCLE	18.469	Loss
Other_TTK_TTK_ST	Q96PE2	ARHGEF17	P33981	TTK	S317	N314H	314	Missense	distal	-3	no	18.998	16.509	EPSD	COSMIC	18.469	Loss
Other_TTK_TTK_ST	Q96PE2	ARHGEF17	P33981	TTK	S317	D311N	311	Missense	distal	-6	no	18.998	18.863	EPSD	COSMIC	18.469	Down-regulation
Other_TTK_TTK_ST	Q96PE2	ARHGEF17	P33981	TTK	S320	G322V	322	Missense	proximal	2	no	20.648	20.533	EPSD	COSMIC;GDSC;CCLE	18.469	Down-regulation
Other_TTK_TTK_ST	Q96PE2	ARHGEF17	P33981	TTK	S320	S317T	317	Missense	distal	-3	no	20.648	22.030	EPSD	COSMIC	18.469	Up-regulation
Other_TTK_TTK_ST	Q96PE2	ARHGEF17	P33981	TTK	S320	N314H	314	Missense	distal	-6	no	20.648	20.963	EPSD	COSMIC	18.469	Up-regulation
Other_TTK_TTK_ST	Q96PE2	ARHGEF17	P33981	TTK	T473	S476I	476	Missense	distal	3	no	18.899	20.751	EPSD	COSMIC;GDSC;CCLE	18.469	Up-regulation
Other_TTK_TTK_ST	Q96PE2	ARHGEF17	P33981	TTK	S507	G504S	504	Missense	distal	-3	no	18.927	19.999	EPSD	COSMIC	18.469	Up-regulation
Other_TTK_TTK_ST	Q96PE2	ARHGEF17	P33981	TTK	S507	P513L	513	Missense	distal	6	no	18.927	18.684	EPSD	COSMIC	18.469	Down-regulation
Other_TTK_TTK_ST	Q96PE2	ARHGEF17	P33981	TTK	S507	G512C	512	Missense	distal	5	no	18.927	16.373	EPSD	COSMIC	18.469	Loss
Other_TTK_TTK_ST	Q96PE2	ARHGEF17	P33981	TTK	S568	A563D	563	Missense	distal	-5	no	19.219	18.809	EPSD	COSMIC	18.469	Down-regulation
Other_TTK_TTK_ST	Q96PE2	ARHGEF17	P33981	TTK	S568	A563T	563	Missense	distal	-5	no	19.219	18.744	EPSD	COSMIC	18.469	Down-regulation
Other_TTK_TTK_ST	Q96PE2	ARHGEF17	P33981	TTK	S568	T561I	561	Missense	distal	-7	no	19.219	17.944	EPSD	COSMIC	18.469	Loss
Other_TTK_TTK_ST	Q96PE2	ARHGEF17	P33981	TTK	S568	L571I	571	Missense	distal	3	no	19.219	20.064	EPSD	COSMIC	18.469	Up-regulation
Other_TTK_TTK_ST	Q96PE2	ARHGEF17	P33981	TTK	T702	L706F	706	Missense	distal	4	no	20.131	18.617	EPSD	COSMIC	18.469	Down-regulation
Other_TTK_TTK_ST	Q96PE2	ARHGEF17	P33981	TTK	S720	P713S	713	Missense	distal	-7	no	17.101	18.887	EPSD	COSMIC	18.469	Gain
Other_TTK_TTK_ST	Q96PE2	ARHGEF17	P33981	TTK	T751	P750L	750	Missense	proximal	-1	no	22.091	22.995	EPSD;PhosphoSitePlus	COSMIC	18.469	Up-regulation
Other_TTK_TTK_ST	Q96PE2	ARHGEF17	P33981	TTK	T751	F753L	753	Missense	proximal	2	no	22.091	22.759	EPSD;PhosphoSitePlus	COSMIC	18.469	Up-regulation
Other_TTK_TTK_ST	Q96PE2	ARHGEF17	P33981	TTK	T780	G778R	778	Missense	proximal	-2	no	19.375	18.900	EPSD	COSMIC	18.469	Down-regulation
Other_TTK_TTK_ST	Q96PE2	ARHGEF17	P33981	TTK	S790	S790G	790	Missense	central	0	yes	20.573	0.000	EPSD	COSMIC	18.469	Loss
Other_TTK_TTK_ST	Q96PE2	ARHGEF17	P33981	TTK	S790	G795V	795	Missense	distal	5	no	20.573	18.385	EPSD	COSMIC	18.469	Loss
Other_TTK_TTK_ST	Q96PE2	ARHGEF17	P33981	TTK	S790	G795R	795	Missense	distal	5	no	20.573	17.566	EPSD	COSMIC	18.469	Loss
Other_TTK_TTK_ST	Q96PE2	ARHGEF17	P33981	TTK	S802	G795V	795	Missense	distal	-7	no	18.021	19.870	EPSD	COSMIC	18.469	Gain
Other_TTK_TTK_ST	Q96PE2	ARHGEF17	P33981	TTK	S802	G806R	806	Missense	distal	4	no	18.021	18.712	EPSD	COSMIC	18.469	Gain
Other_TTK_TTK_ST	Q96PE2	ARHGEF17	P33981	TTK	S802	G795R	795	Missense	distal	-7	no	18.021	18.809	EPSD	COSMIC	18.469	Gain
Other_TTK_TTK_ST	Q96PE2	ARHGEF17	P33981	TTK	S940	D937E	937	Missense	distal	-3	no	16.311	18.532	EPSD	COSMIC	18.469	Gain
Other_TTK_TTK_ST	Q96PE2	ARHGEF17	P33981	TTK	T944	G945C	945	Missense	proximal	1	no	23.911	23.926	EPSD;PhosphoSitePlus	COSMIC	18.469	Up-regulation
Other_TTK_TTK_ST	Q96PE2	ARHGEF17	P33981	TTK	T944	R949W	949	Missense	distal	5	no	23.911	26.204	EPSD;PhosphoSitePlus	COSMIC	18.469	Up-regulation
Other_TTK_TTK_ST	Q96PE2	ARHGEF17	P33981	TTK	T944	D937E	937	Missense	distal	-7	no	23.911	25.377	EPSD;PhosphoSitePlus	COSMIC	18.469	Up-regulation
Other_TTK_TTK_ST	Q96PE2	ARHGEF17	P33981	TTK	T1007	V1006I	1006	Missense	proximal	-1	no	22.406	23.769	PhosphoSitePlus;EPSD	COSMIC	18.469	Up-regulation
Other_TTK_TTK_ST	Q96PE2	ARHGEF17	P33981	TTK	S1345	K1346R	1346	Missense	proximal	1	no	19.401	19.403	EPSD	COSMIC;GDSC;CCLE	18.469	Up-regulation
Other_TTK_TTK_ST	Q96PE2	ARHGEF17	P33981	TTK	S1345	K1352Q	1352	Missense	distal	7	no	19.401	19.358	EPSD	COSMIC	18.469	Down-regulation
Other_TTK_TTK_ST	Q9Y6R1	SLC4A4	P33981	TTK	S61	E56D	56	Missense	distal	-5	no	20.985	19.222	EPSD	COSMIC	18.469	Down-regulation
Other_TTK_TTK_ST	Q9Y6R1	SLC4A4	P33981	TTK	S61	E58K	58	Missense	distal	-3	no	20.985	20.493	EPSD	COSMIC	18.469	Down-regulation
Other_TTK_TTK_ST	Q9Y6R1	SLC4A4	P33981	TTK	S61	K57M	57	Missense	distal	-4	no	20.985	20.960	EPSD	COSMIC	18.469	Down-regulation
Other_TTK_TTK_ST	Q9Y6R1	SLC4A4	P33981	TTK	S77	A73V	73	Missense	distal	-4	no	19.968	19.981	EPSD	COSMIC	18.469	Up-regulation
Other_TTK_TTK_ST	Q9Y6R1	SLC4A4	P33981	TTK	S223	N220S	220	Missense	distal	-3	no	23.254	21.825	EPSD	COSMIC	18.469	Down-regulation
Other_TTK_TTK_ST	Q9Y6R1	SLC4A4	P33981	TTK	S233	R236C	236	Missense	distal	3	no	19.105	16.356	EPSD	COSMIC	18.469	Loss
Other_TTK_TTK_ST	Q9Y6R1	SLC4A4	P33981	TTK	S233	R236H	236	Missense	distal	3	no	19.105	20.655	EPSD	COSMIC	18.469	Up-regulation
Other_TTK_TTK_ST	Q9Y6R1	SLC4A4	P33981	TTK	S233	T239I	239	Missense	distal	6	no	19.105	16.546	EPSD	COSMIC	18.469	Loss
Other_TTK_TTK_ST	Q9Y6R1	SLC4A4	P33981	TTK	S233	R236S	236	Missense	distal	3	no	19.105	18.728	EPSD	COSMIC	18.469	Down-regulation
Other_TTK_TTK_ST	Q9Y6R1	SLC4A4	P33981	TTK	S233	S235G	235	Missense	proximal	2	no	19.105	19.263	EPSD	COSMIC	18.469	Up-regulation
Other_TTK_TTK_ST	Q9Y6R1	SLC4A4	P33981	TTK	S262	P265L	265	Missense	distal	3	no	16.084	21.294	EPSD	COSMIC	18.469	Gain
Other_TTK_TTK_ST	O96017	CHEK2	P33981	TTK	T43	M46T	46	Missense	distal	3	no	20.136	17.216	EPSD	COSMIC	18.469	Loss
Other_TTK_TTK_ST	O96017	CHEK2	P33981	TTK	T43	S49C	49	Missense	distal	6	no	20.136	18.925	EPSD	COSMIC	18.469	Down-regulation
Other_TTK_TTK_ST	O96017	CHEK2	P33981	TTK	T43	S50N	50	Missense	distal	7	no	20.136	20.152	EPSD	COSMIC	18.469	Up-regulation
Other_TTK_TTK_ST	O96017	CHEK2	P33981	TTK	T43	S50T	50	Missense	distal	7	no	20.136	19.423	EPSD	COSMIC	18.469	Down-regulation
Other_TTK_TTK_ST	O96017	CHEK2	P33981	TTK	S52	M46T	46	Missense	distal	-6	no	20.890	20.806	EPSD	COSMIC	18.469	Down-regulation
Other_TTK_TTK_ST	O96017	CHEK2	P33981	TTK	S52	S52P	52	Missense	central	0	yes	20.890	0.000	EPSD	COSMIC;GDSC;CCLE	18.469	Loss
Other_TTK_TTK_ST	O96017	CHEK2	P33981	TTK	S52	S49C	49	Missense	distal	-3	no	20.890	19.764	EPSD	COSMIC	18.469	Down-regulation
Other_TTK_TTK_ST	O96017	CHEK2	P33981	TTK	S52	S50N	50	Missense	proximal	-2	no	20.890	21.307	EPSD	COSMIC	18.469	Up-regulation
Other_TTK_TTK_ST	O96017	CHEK2	P33981	TTK	S52	S50T	50	Missense	proximal	-2	no	20.890	21.245	EPSD	COSMIC	18.469	Up-regulation
Other_TTK_TTK_ST	O96017	CHEK2	P33981	TTK	T68	Q69R	69	Missense	proximal	1	no	22.982	22.998	PhosphoSitePlus	COSMIC	18.469	Up-regulation
Other_TTK_TTK_ST	O96017	CHEK2	P33981	TTK	S357	D361E	361	Missense	distal	4	no	18.229	19.519	EPSD	COSMIC	18.469	Gain
Other_TTK_TTK_ST	O96017	CHEK2	P33981	TTK	S435	K437Q	437	Missense	proximal	2	no	19.782	20.494	EPSD	COSMIC	18.469	Up-regulation
Other_TTK_TTK_ST	O96017	CHEK2	P33981	TTK	S435	T441I	441	Missense	distal	6	no	19.782	17.224	EPSD	COSMIC	18.469	Loss
Other_TTK_TTK_ST	O96017	CHEK2	P33981	TTK	S442	I448S	448	Missense	distal	6	no	21.013	22.077	EPSD	COSMIC	18.469	Up-regulation
Other_TTK_TTK_ST	O96017	CHEK2	P33981	TTK	S442	K437Q	437	Missense	distal	-5	no	21.013	20.370	EPSD	COSMIC	18.469	Down-regulation
Other_TTK_TTK_ST	O96017	CHEK2	P33981	TTK	S442	I448T	448	Missense	distal	6	no	21.013	23.572	EPSD	COSMIC	18.469	Up-regulation
Other_TTK_TTK_ST	O96017	CHEK2	P33981	TTK	S442	T441I	441	Missense	proximal	-1	no	21.013	19.058	EPSD	COSMIC	18.469	Down-regulation
Other_TTK_TTK_ST	O96017	CHEK2	P33981	TTK	S442	G443V	443	Missense	proximal	1	no	21.013	21.043	EPSD	COSMIC	18.469	Up-regulation
Other_TTK_TTK_ST	O96017	CHEK2	P33981	TTK	T517	R519Q	519	Missense	proximal	2	no	17.807	19.480	EPSD	COSMIC	18.469	Gain
Other_TTK_TTK_ST	O96017	CHEK2	P33981	TTK	T517	R523P	523	Missense	distal	6	no	17.807	18.496	EPSD	COSMIC	18.469	Gain
Other_TTK_TTK_ST	Q6IBW4	NCAPH2	P33981	TTK	S95	R90Q	90	Missense	distal	-5	no	20.265	20.908	EPSD	COSMIC	18.469	Up-regulation
Other_TTK_TTK_ST	Q6IBW4	NCAPH2	P33981	TTK	S95	R90P	90	Missense	distal	-5	no	20.265	19.786	EPSD	COSMIC	18.469	Down-regulation
Other_TTK_TTK_ST	Q6IBW4	NCAPH2	P33981	TTK	S95	K88R	88	Missense	distal	-7	no	20.265	20.868	EPSD	COSMIC;GDSC;CCLE	18.469	Up-regulation
Other_TTK_TTK_ST	Q6IBW4	NCAPH2	P33981	TTK	S96	R90Q	90	Missense	distal	-6	no	22.429	22.209	EPSD	COSMIC	18.469	Down-regulation
Other_TTK_TTK_ST	Q6IBW4	NCAPH2	P33981	TTK	S96	R90P	90	Missense	distal	-6	no	22.429	22.391	EPSD	COSMIC	18.469	Down-regulation
Other_TTK_TTK_ST	Q6IBW4	NCAPH2	P33981	TTK	T138	D136E	136	Missense	proximal	-2	no	27.160	27.280	EPSD	COSMIC	18.469	Up-regulation
Other_TTK_TTK_ST	Q6IBW4	NCAPH2	P33981	TTK	T403	R409K	409	Missense	distal	6	no	23.422	24.370	EPSD	COSMIC	18.469	Up-regulation
Other_TTK_TTK_ST	Q6IBW4	NCAPH2	P33981	TTK	T403	R405W	405	Missense	proximal	2	no	23.422	23.058	EPSD	COSMIC	18.469	Down-regulation
Other_TTK_TTK_ST	Q6IBW4	NCAPH2	P33981	TTK	S428	H424R	424	Missense	distal	-4	no	20.449	20.422	EPSD	COSMIC	18.469	Down-regulation
Other_TTK_TTK_ST	Q6IBW4	NCAPH2	P33981	TTK	S428	A434T	434	Missense	distal	6	no	20.449	20.552	EPSD	COSMIC	18.469	Up-regulation
Other_TTK_TTK_ST	Q96E14	RMI2	P33981	TTK	S112	S112C	112	Missense	central	0	yes	22.096	0.000	PhosphoSitePlus	COSMIC	18.469	Loss
Other_TTK_TTK_ST	Q96E14	RMI2	P33981	TTK	S112	Q118L	118	Missense	distal	6	no	22.096	21.244	PhosphoSitePlus	COSMIC;GDSC;CCLE	18.469	Down-regulation
Other_TTK_TTK_ST	Q96E14	RMI2	P33981	TTK	S112	V107A	107	Missense	distal	-5	no	22.096	23.260	PhosphoSitePlus	COSMIC	18.469	Up-regulation
Other_TTK_TTK_ST	Q96E14	RMI2	P33981	TTK	S112	C111S	111	Missense	proximal	-1	no	22.096	24.893	PhosphoSitePlus	COSMIC	18.469	Up-regulation
Other_TTK_TTK_ST	Q96E14	RMI2	P33981	TTK	S112	M105I	105	Missense	distal	-7	no	22.096	20.954	PhosphoSitePlus	COSMIC	18.469	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	P35367	HRH1	P17252	PRKCA	S94	P98S	98	Missense	distal	4	no	16.736	16.936	EPSD	COSMIC	16.704	Up-regulation
AGC_PKC_PKCa_PRKCA_ST	P35367	HRH1	P17252	PRKCA	S94	M90I	90	Missense	distal	-4	no	16.736	16.021	EPSD	COSMIC	16.704	Loss
AGC_PKC_PKCa_PRKCA_ST	P35367	HRH1	P17252	PRKCA	T140	R139H	139	Missense	proximal	-1	no	16.754	16.431	EPSD	COSMIC	16.704	Loss
AGC_PKC_PKCa_PRKCA_ST	P35367	HRH1	P17252	PRKCA	T142	L149M	149	Missense	distal	7	no	17.119	17.127	EPSD	COSMIC	16.704	Up-regulation
AGC_PKC_PKCa_PRKCA_ST	P35367	HRH1	P17252	PRKCA	T142	R139H	139	Missense	distal	-3	no	17.119	13.263	EPSD	COSMIC	16.704	Loss
AGC_PKC_PKCa_PRKCA_ST	P35367	HRH1	P17252	PRKCA	S271	G269R	269	Missense	proximal	-2	no	16.162	19.034	EPSD	COSMIC	16.704	Gain
AGC_PKC_PKCa_PRKCA_ST	P35367	HRH1	P17252	PRKCA	S378	G383V	383	Missense	distal	5	no	16.986	16.845	EPSD	COSMIC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	P35367	HRH1	P17252	PRKCA	S378	D385E	385	Missense	distal	7	no	16.986	16.934	EPSD	COSMIC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	P35367	HRH1	P17252	PRKCA	S380	G383V	383	Missense	distal	3	no	17.905	16.690	EPSD	COSMIC	16.704	Loss
AGC_PKC_PKCa_PRKCA_ST	P35367	HRH1	P17252	PRKCA	S380	D385E	385	Missense	distal	5	no	17.905	17.997	EPSD	COSMIC	16.704	Up-regulation
AGC_PKC_PKCa_PRKCA_ST	P35367	HRH1	P17252	PRKCA	S396	S396P	396	Missense	central	0	yes	21.552	0.000	EPSD;PhosphoSitePlus	COSMIC	16.704	Loss
AGC_PKC_PKCa_PRKCA_ST	P35367	HRH1	P17252	PRKCA	S396	S403F	403	Missense	distal	7	no	21.552	21.489	EPSD;PhosphoSitePlus	COSMIC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	P35367	HRH1	P17252	PRKCA	S396	R395S	395	Missense	proximal	-1	no	21.552	21.165	EPSD;PhosphoSitePlus	COSMIC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	P35367	HRH1	P17252	PRKCA	S396	R395L	395	Missense	proximal	-1	no	21.552	20.745	EPSD;PhosphoSitePlus	COSMIC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	P29474	NOS3	P17252	PRKCA	S260	P265L	265	Missense	distal	5	no	22.224	21.874	EPSD	COSMIC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	P29474	NOS3	P17252	PRKCA	S260	D264N	264	Missense	distal	4	no	22.224	21.866	EPSD	COSMIC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	P29474	NOS3	P17252	PRKCA	S260	G259V	259	Missense	proximal	-1	no	22.224	20.513	EPSD	COSMIC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	P29474	NOS3	P17252	PRKCA	S483	G489S	489	Missense	distal	6	no	17.071	17.149	EPSD	COSMIC	16.704	Up-regulation
AGC_PKC_PKCa_PRKCA_ST	P29474	NOS3	P17252	PRKCA	S483	G489D	489	Missense	distal	6	no	17.071	17.131	EPSD	COSMIC	16.704	Up-regulation
AGC_PKC_PKCa_PRKCA_ST	P29474	NOS3	P17252	PRKCA	S483	A485T	485	Missense	proximal	2	no	17.071	16.959	EPSD	COSMIC;GDSC;CCLE	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	P29474	NOS3	P17252	PRKCA	T495	G489S	489	Missense	distal	-6	no	21.488	21.522	PhosphoSitePlus	COSMIC	16.704	Up-regulation
AGC_PKC_PKCa_PRKCA_ST	P29474	NOS3	P17252	PRKCA	T495	G489D	489	Missense	distal	-6	no	21.488	21.438	PhosphoSitePlus	COSMIC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	P29474	NOS3	P17252	PRKCA	S600	G595S	595	Missense	distal	-5	no	18.159	18.022	EPSD	COSMIC;GDSC;CCLE	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	P29474	NOS3	P17252	PRKCA	S600	R602W	602	Missense	proximal	2	no	18.159	12.719	EPSD	COSMIC	16.704	Loss
AGC_PKC_PKCa_PRKCA_ST	P29474	NOS3	P17252	PRKCA	S600	S594F	594	Missense	distal	-6	no	18.159	18.074	EPSD	COSMIC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	P29474	NOS3	P17252	PRKCA	S615	K610Q	610	Missense	distal	-5	no	18.397	18.258	EPSD	COSMIC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	P29474	NOS3	P17252	PRKCA	S625	V623I	623	Missense	proximal	-2	no	21.855	21.109	EPSD	COSMIC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	P29474	NOS3	P17252	PRKCA	S625	S625F	625	Missense	central	0	yes	21.855	0.000	EPSD	COSMIC;GDSC;CCLE	16.704	Loss
AGC_PKC_PKCa_PRKCA_ST	P29474	NOS3	P17252	PRKCA	S633	D637H	637	Missense	distal	4	no	18.170	18.487	EPSD	COSMIC	16.704	Up-regulation
AGC_PKC_PKCa_PRKCA_ST	P29474	NOS3	P17252	PRKCA	S633	N635T	635	Missense	proximal	2	no	18.170	18.730	EPSD	COSMIC	16.704	Up-regulation
AGC_PKC_PKCa_PRKCA_ST	P29474	NOS3	P17252	PRKCA	S725	A719T	719	Missense	distal	-6	no	17.751	17.662	EPSD	COSMIC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	P29474	NOS3	P17252	PRKCA	S738	G743I	743	Missense	distal	5	no	16.757	16.703	EPSD	COSMIC	16.704	Loss
AGC_PKC_PKCa_PRKCA_ST	P09758	TACSTD2	P17252	PRKCA	S269	A275T	275	Missense	distal	6	no	17.276	17.199	EPSD	COSMIC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	P09758	TACSTD2	P17252	PRKCA	S269	P266L	266	Missense	distal	-3	no	17.276	16.769	EPSD	COSMIC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	P09758	TACSTD2	P17252	PRKCA	S269	G276S	276	Missense	distal	7	no	17.276	17.255	EPSD	COSMIC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	P09758	TACSTD2	P17252	PRKCA	S269	E263K	263	Missense	distal	-6	no	17.276	17.344	EPSD	COSMIC	16.704	Up-regulation
AGC_PKC_PKCa_PRKCA_ST	Q9BR39	JPH2	P17252	PRKCA	S235	V239M	239	Missense	distal	4	no	18.470	19.842	EPSD	COSMIC	16.704	Up-regulation
AGC_PKC_PKCa_PRKCA_ST	Q9BR39	JPH2	P17252	PRKCA	S235	R231Q	231	Missense	distal	-4	no	18.470	18.093	EPSD	COSMIC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	Q9BR39	JPH2	P17252	PRKCA	S235	R232H	232	Missense	distal	-3	no	18.470	14.614	EPSD	COSMIC	16.704	Loss
AGC_PKC_PKCa_PRKCA_ST	Q9BR39	JPH2	P17252	PRKCA	S238	R245C	245	Missense	distal	7	no	17.579	17.356	EPSD	COSMIC;CCLE	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	Q9BR39	JPH2	P17252	PRKCA	S238	V239M	239	Missense	proximal	1	no	17.579	17.240	EPSD	COSMIC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	Q9BR39	JPH2	P17252	PRKCA	S238	R231Q	231	Missense	distal	-7	no	17.579	17.571	EPSD	COSMIC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	Q9BR39	JPH2	P17252	PRKCA	S238	R232H	232	Missense	distal	-6	no	17.579	17.511	EPSD	COSMIC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	Q9BR39	JPH2	P17252	PRKCA	S241	R245C	245	Missense	distal	4	no	20.964	19.563	EPSD	COSMIC;CCLE	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	Q9BR39	JPH2	P17252	PRKCA	S241	V239M	239	Missense	proximal	-2	no	20.964	21.825	EPSD	COSMIC	16.704	Up-regulation
AGC_PKC_PKCa_PRKCA_ST	Q9BR39	JPH2	P17252	PRKCA	S244	R245C	245	Missense	proximal	1	no	17.352	14.516	EPSD	COSMIC;CCLE	16.704	Loss
AGC_PKC_PKCa_PRKCA_ST	Q9BR39	JPH2	P17252	PRKCA	S244	V239M	239	Missense	distal	-5	no	17.352	17.750	EPSD	COSMIC	16.704	Up-regulation
AGC_PKC_PKCa_PRKCA_ST	Q9BR39	JPH2	P17252	PRKCA	S247	R245C	245	Missense	proximal	-2	no	17.992	16.293	EPSD	COSMIC;CCLE	16.704	Loss
AGC_PKC_PKCa_PRKCA_ST	Q9BR39	JPH2	P17252	PRKCA	S306	F303I	303	Missense	distal	-3	no	18.147	16.280	EPSD	COSMIC	16.704	Loss
AGC_PKC_PKCa_PRKCA_ST	Q9BR39	JPH2	P17252	PRKCA	S306	S309F	309	Missense	distal	3	no	18.147	17.634	EPSD	COSMIC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	Q9BR39	JPH2	P17252	PRKCA	S359	R352G	352	Missense	distal	-7	no	19.136	19.127	EPSD	COSMIC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	Q9BR39	JPH2	P17252	PRKCA	S369	E367K	367	Missense	proximal	-2	no	15.255	17.754	EPSD	COSMIC	16.704	Gain
AGC_PKC_PKCa_PRKCA_ST	Q9BR39	JPH2	P17252	PRKCA	S534	S527F	527	Missense	distal	-7	no	19.046	19.038	EPSD	COSMIC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	Q9BR39	JPH2	P17252	PRKCA	S534	G529S	529	Missense	distal	-5	no	19.046	18.910	EPSD	COSMIC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	Q9BR39	JPH2	P17252	PRKCA	S534	R537H	537	Missense	distal	3	no	19.046	18.334	EPSD	COSMIC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	Q9BR39	JPH2	P17252	PRKCA	T540	R537H	537	Missense	distal	-3	no	18.930	15.074	EPSD	COSMIC	16.704	Loss
AGC_PKC_PKCa_PRKCA_ST	Q9BR39	JPH2	P17252	PRKCA	T540	R542H	542	Missense	proximal	2	no	18.930	13.907	EPSD	COSMIC	16.704	Loss
AGC_PKC_PKCa_PRKCA_ST	P29966	MARCKS	P17252	PRKCA	T8	A10T	10	Missense	proximal	2	no	17.088	16.976	EPSD	COSMIC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	P29966	MARCKS	P17252	PRKCA	T8	A15T	15	Missense	distal	7	no	17.088	17.096	EPSD	COSMIC;CCLE	16.704	Up-regulation
AGC_PKC_PKCa_PRKCA_ST	Q92879	CELF1	P17252	PRKCA	S28	L32M	32	Missense	distal	4	no	18.731	19.574	EPSD;PhosphoSitePlus	COSMIC	16.704	Up-regulation
AGC_PKC_PKCa_PRKCA_ST	Q92879	CELF1	P17252	PRKCA	S28	R33Q	33	Missense	distal	5	no	18.731	18.723	EPSD;PhosphoSitePlus	COSMIC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	Q92879	CELF1	P17252	PRKCA	S28	P24L	24	Missense	distal	-4	no	18.731	18.471	EPSD;PhosphoSitePlus	COSMIC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	Q92879	CELF1	P17252	PRKCA	S28	R33W	33	Missense	distal	5	no	18.731	18.223	EPSD;PhosphoSitePlus	COSMIC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	Q92879	CELF1	P17252	PRKCA	S52	Q53K	53	Missense	proximal	1	no	17.180	17.334	EPSD;PhosphoSitePlus	COSMIC	16.704	Up-regulation
AGC_PKC_PKCa_PRKCA_ST	Q92879	CELF1	P17252	PRKCA	S52	D50E	50	Missense	proximal	-2	no	17.180	16.472	EPSD;PhosphoSitePlus	COSMIC	16.704	Loss
AGC_PKC_PKCa_PRKCA_ST	Q92879	CELF1	P17252	PRKCA	S52	R49T	49	Missense	distal	-3	no	17.180	13.017	EPSD;PhosphoSitePlus	COSMIC	16.704	Loss
AGC_PKC_PKCa_PRKCA_ST	Q92879	CELF1	P17252	PRKCA	S129	S130L	130	Missense	proximal	1	no	16.705	17.531	EPSD	COSMIC	16.704	Up-regulation
AGC_PKC_PKCa_PRKCA_ST	Q92879	CELF1	P17252	PRKCA	S129	S129L	129	Missense	central	0	yes	16.705	0.000	EPSD	COSMIC	16.704	Loss
AGC_PKC_PKCa_PRKCA_ST	Q92879	CELF1	P17252	PRKCA	S297	S299R	299	Missense	proximal	2	no	14.926	19.546	EPSD	COSMIC	16.704	Gain
AGC_PKC_PKCa_PRKCA_ST	Q92879	CELF1	P17252	PRKCA	S300	S299R	299	Missense	proximal	-1	no	16.671	17.058	EPSD;PhosphoSitePlus	COSMIC	16.704	Gain
AGC_PKC_PKCa_PRKCA_ST	Q92879	CELF1	P17252	PRKCA	S300	S302R	302	Missense	proximal	2	no	16.671	21.291	EPSD;PhosphoSitePlus	COSMIC	16.704	Gain
AGC_PKC_PKCa_PRKCA_ST	Q92879	CELF1	P17252	PRKCA	S300	S304R	304	Missense	distal	4	no	16.671	16.917	EPSD;PhosphoSitePlus	COSMIC	16.704	Gain
AGC_PKC_PKCa_PRKCA_ST	Q92879	CELF1	P17252	PRKCA	S300	S305R	305	Missense	distal	5	no	16.671	16.813	EPSD;PhosphoSitePlus	COSMIC	16.704	Gain
AGC_PKC_PKCa_PRKCA_ST	Q92879	CELF1	P17252	PRKCA	S302	S299R	299	Missense	distal	-3	no	14.298	17.168	EPSD;PhosphoSitePlus	COSMIC	16.704	Gain
AGC_PKC_PKCa_PRKCA_ST	Q92879	CELF1	P17252	PRKCA	S302	S304R	304	Missense	proximal	2	no	14.298	18.918	EPSD;PhosphoSitePlus	COSMIC	16.704	Gain
AGC_PKC_PKCa_PRKCA_ST	Q92879	CELF1	P17252	PRKCA	S303	S299R	299	Missense	distal	-4	no	16.680	16.873	EPSD	COSMIC	16.704	Gain
AGC_PKC_PKCa_PRKCA_ST	Q92879	CELF1	P17252	PRKCA	S303	S302R	302	Missense	proximal	-1	no	16.680	17.068	EPSD	COSMIC	16.704	Gain
AGC_PKC_PKCa_PRKCA_ST	Q92879	CELF1	P17252	PRKCA	S303	S304R	304	Missense	proximal	1	no	16.680	17.854	EPSD	COSMIC	16.704	Gain
AGC_PKC_PKCa_PRKCA_ST	Q92879	CELF1	P17252	PRKCA	S303	S305R	305	Missense	proximal	2	no	16.680	21.300	EPSD	COSMIC	16.704	Gain
AGC_PKC_PKCa_PRKCA_ST	Q92879	CELF1	P17252	PRKCA	S306	S304R	304	Missense	proximal	-2	no	13.610	16.912	EPSD	COSMIC	16.704	Gain
AGC_PKC_PKCa_PRKCA_ST	P11387	TOP1	P17252	PRKCA	S2	L6F	6	Missense	distal	4	no	17.590	18.021	EPSD	COSMIC	16.704	Up-regulation
AGC_PKC_PKCa_PRKCA_ST	P11387	TOP1	P17252	PRKCA	S2	D9G	9	Missense	distal	7	no	17.590	17.610	EPSD	COSMIC	16.704	Up-regulation
AGC_PKC_PKCa_PRKCA_ST	P11387	TOP1	P17252	PRKCA	S2	L6V	6	Missense	distal	4	no	17.590	17.061	EPSD	COSMIC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	P11387	TOP1	P17252	PRKCA	S10	L6F	6	Missense	distal	-4	no	16.840	17.213	EPSD	COSMIC	16.704	Up-regulation
AGC_PKC_PKCa_PRKCA_ST	P11387	TOP1	P17252	PRKCA	S10	D9G	9	Missense	proximal	-1	no	16.840	17.584	EPSD	COSMIC	16.704	Up-regulation
AGC_PKC_PKCa_PRKCA_ST	P11387	TOP1	P17252	PRKCA	S10	L6V	6	Missense	distal	-4	no	16.840	16.799	EPSD	COSMIC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	P11387	TOP1	P17252	PRKCA	S21	D20Y	20	Missense	proximal	-1	no	19.040	19.086	PhosphoSitePlus	COSMIC	16.704	Up-regulation
AGC_PKC_PKCa_PRKCA_ST	P11387	TOP1	P17252	PRKCA	S21	H22Q	22	Missense	proximal	1	no	19.040	19.736	PhosphoSitePlus	COSMIC	16.704	Up-regulation
AGC_PKC_PKCa_PRKCA_ST	P11387	TOP1	P17252	PRKCA	S21	D20A	20	Missense	proximal	-1	no	19.040	18.976	PhosphoSitePlus	COSMIC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	P11387	TOP1	P17252	PRKCA	S74	H81Y	81	Missense	distal	7	no	17.158	17.177	EPSD	COSMIC	16.704	Up-regulation
AGC_PKC_PKCa_PRKCA_ST	P11387	TOP1	P17252	PRKCA	S74	D79E	79	Missense	distal	5	no	17.158	17.250	EPSD	COSMIC	16.704	Up-regulation
AGC_PKC_PKCa_PRKCA_ST	P11387	TOP1	P17252	PRKCA	S432	I435V	435	Missense	distal	3	no	16.651	17.346	EPSD	COSMIC	16.704	Gain
AGC_PKC_PKCa_PRKCA_ST	P11387	TOP1	P17252	PRKCA	T446	R448W	448	Missense	proximal	2	no	18.699	13.259	EPSD	COSMIC	16.704	Loss
AGC_PKC_PKCa_PRKCA_ST	P11387	TOP1	P17252	PRKCA	T446	E445G	445	Missense	proximal	-1	no	18.699	18.929	EPSD	COSMIC	16.704	Up-regulation
AGC_PKC_PKCa_PRKCA_ST	P11387	TOP1	P17252	PRKCA	T446	R449Q	449	Missense	distal	3	no	18.699	16.246	EPSD	COSMIC	16.704	Loss
AGC_PKC_PKCa_PRKCA_ST	P11387	TOP1	P17252	PRKCA	S506	S506L	506	Missense	central	0	yes	18.819	0.000	EPSD	COSMIC	16.704	Loss
AGC_PKC_PKCa_PRKCA_ST	P11387	TOP1	P17252	PRKCA	S534	Y537H	537	Missense	distal	3	no	20.451	22.007	EPSD	COSMIC	16.704	Up-regulation
AGC_PKC_PKCa_PRKCA_ST	P11387	TOP1	P17252	PRKCA	S534	R536G	536	Missense	proximal	2	no	20.451	15.206	EPSD	COSMIC	16.704	Loss
AGC_PKC_PKCa_PRKCA_ST	P11387	TOP1	P17252	PRKCA	S534	V541I	541	Missense	distal	7	no	20.451	20.354	EPSD	COSMIC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	P11387	TOP1	P17252	PRKCA	S534	I535M	535	Missense	proximal	1	no	20.451	19.400	EPSD	COSMIC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	P11387	TOP1	P17252	PRKCA	S534	D528G	528	Missense	distal	-6	no	20.451	20.501	EPSD	COSMIC	16.704	Up-regulation
AGC_PKC_PKCa_PRKCA_ST	P11387	TOP1	P17252	PRKCA	S534	G531R	531	Missense	distal	-3	no	20.451	23.713	EPSD	COSMIC	16.704	Up-regulation
AGC_PKC_PKCa_PRKCA_ST	P11387	TOP1	P17252	PRKCA	S686	T680M	680	Missense	distal	-6	no	19.270	19.393	EPSD	COSMIC	16.704	Up-regulation
AGC_PKC_PKCa_PRKCA_ST	P11387	TOP1	P17252	PRKCA	S686	K682N	682	Missense	distal	-4	no	19.270	18.712	EPSD	COSMIC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	P11387	TOP1	P17252	PRKCA	S686	R693I	693	Missense	distal	7	no	19.270	19.071	EPSD	COSMIC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	Q96PH1	NOX5	P17252	PRKCA	T32	W30R	30	Missense	proximal	-2	no	16.877	18.875	EPSD	COSMIC;CCLE	16.704	Up-regulation
AGC_PKC_PKCa_PRKCA_ST	Q96PH1	NOX5	P17252	PRKCA	T32	R26K	26	Missense	distal	-6	no	16.877	16.870	EPSD	COSMIC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	Q96PH1	NOX5	P17252	PRKCA	S521	F522L	522	Missense	proximal	1	no	18.900	18.242	EPSD	COSMIC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	Q96PH1	NOX5	P17252	PRKCA	S536	G529S	529	Missense	distal	-7	no	18.737	18.741	EPSD	COSMIC	16.704	Up-regulation
AGC_PKC_PKCa_PRKCA_ST	Q96PH1	NOX5	P17252	PRKCA	S536	R537S	537	Missense	proximal	1	no	18.737	17.563	EPSD	COSMIC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	Q96PH1	NOX5	P17252	PRKCA	S536	M541I	541	Missense	distal	5	no	18.737	18.416	EPSD	COSMIC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	Q96PH1	NOX5	P17252	PRKCA	S536	R530S	530	Missense	distal	-6	no	18.737	18.664	EPSD	COSMIC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	Q96PH1	NOX5	P17252	PRKCA	S536	V539L	539	Missense	distal	3	no	18.737	18.353	EPSD	COSMIC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	Q96PH1	NOX5	P17252	PRKCA	S536	T540I	540	Missense	distal	4	no	18.737	17.723	EPSD	COSMIC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	Q96PH1	NOX5	P17252	PRKCA	T540	S547L	547	Missense	distal	7	no	18.316	18.319	EPSD	COSMIC	16.704	Up-regulation
AGC_PKC_PKCa_PRKCA_ST	Q96PH1	NOX5	P17252	PRKCA	T540	R537S	537	Missense	distal	-3	no	18.316	15.446	EPSD	COSMIC	16.704	Loss
AGC_PKC_PKCa_PRKCA_ST	Q96PH1	NOX5	P17252	PRKCA	T540	M541I	541	Missense	proximal	1	no	18.316	19.367	EPSD	COSMIC	16.704	Up-regulation
AGC_PKC_PKCa_PRKCA_ST	Q96PH1	NOX5	P17252	PRKCA	T540	V539L	539	Missense	proximal	-1	no	18.316	19.359	EPSD	COSMIC	16.704	Up-regulation
AGC_PKC_PKCa_PRKCA_ST	Q96PH1	NOX5	P17252	PRKCA	T540	T540I	540	Missense	central	0	yes	18.316	0.000	EPSD	COSMIC	16.704	Loss
AGC_PKC_PKCa_PRKCA_ST	Q96PH1	NOX5	P17252	PRKCA	S544	S547L	547	Missense	distal	3	no	22.733	21.886	EPSD	COSMIC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	Q96PH1	NOX5	P17252	PRKCA	S544	R537S	537	Missense	distal	-7	no	22.733	22.727	EPSD	COSMIC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	Q96PH1	NOX5	P17252	PRKCA	S544	M541I	541	Missense	distal	-3	no	22.733	21.217	EPSD	COSMIC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	Q96PH1	NOX5	P17252	PRKCA	S544	K549R	549	Missense	distal	5	no	22.733	22.589	EPSD	COSMIC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	Q96PH1	NOX5	P17252	PRKCA	S544	V539L	539	Missense	distal	-5	no	22.733	23.169	EPSD	COSMIC	16.704	Up-regulation
AGC_PKC_PKCa_PRKCA_ST	Q96PH1	NOX5	P17252	PRKCA	S544	T540I	540	Missense	distal	-4	no	22.733	22.952	EPSD	COSMIC	16.704	Up-regulation
AGC_PKC_PKCa_PRKCA_ST	Q96PH1	NOX5	P17252	PRKCA	S548	S547L	547	Missense	proximal	-1	no	18.034	17.615	EPSD	COSMIC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	Q96PH1	NOX5	P17252	PRKCA	S548	M541I	541	Missense	distal	-7	no	18.034	18.023	EPSD	COSMIC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	Q96PH1	NOX5	P17252	PRKCA	S548	K549R	549	Missense	proximal	1	no	18.034	17.997	EPSD	COSMIC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	Q96PH1	NOX5	P17252	PRKCA	S705	I706T	706	Missense	proximal	1	no	17.000	15.664	EPSD	COSMIC	16.704	Loss
AGC_PKC_PKCa_PRKCA_ST	Q96PH1	NOX5	P17252	PRKCA	S705	T711M	711	Missense	distal	6	no	17.000	17.047	EPSD	COSMIC	16.704	Up-regulation
AGC_PKC_PKCa_PRKCA_ST	Q96PH1	NOX5	P17252	PRKCA	S705	G708R	708	Missense	distal	3	no	17.000	17.640	EPSD	COSMIC	16.704	Up-regulation
AGC_PKC_PKCa_PRKCA_ST	P37802	TAGLN2	P17252	PRKCA	T180	I174M	174	Missense	distal	-6	no	16.654	16.749	EPSD;PhosphoSitePlus	COSMIC	16.704	Gain
AGC_PKC_PKCa_PRKCA_ST	O76090	BEST1	P17252	PRKCA	S16	N11D	11	Missense	distal	-5	no	19.974	19.945	EPSD	COSMIC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	O76090	BEST1	P17252	PRKCA	S358	Q353K	353	Missense	distal	-5	no	22.219	22.359	PhosphoSitePlus	COSMIC	16.704	Up-regulation
AGC_PKC_PKCa_PRKCA_ST	O76090	BEST1	P17252	PRKCA	S358	R356Q	356	Missense	proximal	-2	no	22.219	20.460	PhosphoSitePlus	COSMIC;CCLE	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	O76090	BEST1	P17252	PRKCA	S358	M360T	360	Missense	proximal	2	no	22.219	21.857	PhosphoSitePlus	COSMIC;CCLE	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	Q15080	NCF4	P17252	PRKCA	T154	R153H	153	Missense	proximal	-1	no	20.732	20.409	EPSD;PhosphoSitePlus	COSMIC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	Q15080	NCF4	P17252	PRKCA	S159	R153H	153	Missense	distal	-6	no	16.862	16.794	EPSD	COSMIC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	Q15080	NCF4	P17252	PRKCA	S315	P314L	314	Missense	proximal	-1	no	17.857	17.737	PhosphoSitePlus;EPSD	COSMIC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	P04083	ANXA1	P17252	PRKCA	S27	G33R	33	Missense	distal	6	no	20.046	20.195	EPSD;PhosphoSitePlus	COSMIC	16.704	Up-regulation
AGC_PKC_PKCa_PRKCA_ST	P04083	ANXA1	P17252	PRKCA	S28	G33R	33	Missense	distal	5	no	17.015	17.296	PhosphoSitePlus;EPSD	COSMIC	16.704	Up-regulation
AGC_PKC_PKCa_PRKCA_ST	P16144	ITGB4	P17252	PRKCA	S7	G3R	3	Missense	distal	-4	no	18.162	18.264	EPSD	COSMIC	16.704	Up-regulation
AGC_PKC_PKCa_PRKCA_ST	P16144	ITGB4	P17252	PRKCA	S7	A10D	10	Missense	distal	3	no	18.162	18.035	EPSD	COSMIC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	P16144	ITGB4	P17252	PRKCA	S99	S102P	102	Missense	distal	3	no	18.291	18.152	EPSD	COSMIC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	P16144	ITGB4	P17252	PRKCA	S99	T94I	94	Missense	distal	-5	no	18.291	17.819	EPSD	COSMIC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	P16144	ITGB4	P17252	PRKCA	S102	S102P	102	Missense	central	0	yes	18.480	0.000	EPSD	COSMIC	16.704	Loss
AGC_PKC_PKCa_PRKCA_ST	P16144	ITGB4	P17252	PRKCA	S102	V108A	108	Missense	distal	6	no	18.480	18.599	EPSD	COSMIC	16.704	Up-regulation
AGC_PKC_PKCa_PRKCA_ST	P16144	ITGB4	P17252	PRKCA	S377	A374S	374	Missense	distal	-3	no	17.475	19.054	EPSD	COSMIC	16.704	Up-regulation
AGC_PKC_PKCa_PRKCA_ST	P16144	ITGB4	P17252	PRKCA	S377	T383I	383	Missense	distal	6	no	17.475	17.489	EPSD	COSMIC	16.704	Up-regulation
AGC_PKC_PKCa_PRKCA_ST	P16144	ITGB4	P17252	PRKCA	S397	E404K	404	Missense	distal	7	no	17.492	17.638	EPSD	COSMIC;GDSC;CCLE	16.704	Up-regulation
AGC_PKC_PKCa_PRKCA_ST	P16144	ITGB4	P17252	PRKCA	S397	T393M	393	Missense	distal	-4	no	17.492	18.426	EPSD	COSMIC;GDSC	16.704	Up-regulation
AGC_PKC_PKCa_PRKCA_ST	P16144	ITGB4	P17252	PRKCA	S397	R401Q	401	Missense	distal	4	no	17.492	17.275	EPSD	COSMIC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	P16144	ITGB4	P17252	PRKCA	S397	H399Y	399	Missense	proximal	2	no	17.492	18.020	EPSD	COSMIC	16.704	Up-regulation
AGC_PKC_PKCa_PRKCA_ST	P16144	ITGB4	P17252	PRKCA	S397	E404Q	404	Missense	distal	7	no	17.492	17.583	EPSD	COSMIC	16.704	Up-regulation
AGC_PKC_PKCa_PRKCA_ST	P16144	ITGB4	P17252	PRKCA	S821	V816M	816	Missense	distal	-5	no	17.361	17.758	EPSD	COSMIC	16.704	Up-regulation
AGC_PKC_PKCa_PRKCA_ST	P16144	ITGB4	P17252	PRKCA	S1002	G1004R	1004	Missense	proximal	2	no	11.621	16.866	EPSD	COSMIC	16.704	Gain
AGC_PKC_PKCa_PRKCA_ST	P16144	ITGB4	P17252	PRKCA	S1140	K1142N	1142	Missense	proximal	2	no	18.713	13.764	EPSD	COSMIC;GDSC;CCLE	16.704	Loss
AGC_PKC_PKCa_PRKCA_ST	P16144	ITGB4	P17252	PRKCA	S1140	A1135V	1135	Missense	distal	-5	no	18.713	18.629	EPSD	COSMIC;GDSC;CCLE	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	P16144	ITGB4	P17252	PRKCA	S1212	E1218K	1218	Missense	distal	6	no	17.703	17.797	EPSD	COSMIC	16.704	Up-regulation
AGC_PKC_PKCa_PRKCA_ST	P16144	ITGB4	P17252	PRKCA	T1297	G1303R	1303	Missense	distal	6	no	18.072	18.222	EPSD	COSMIC;GDSC	16.704	Up-regulation
AGC_PKC_PKCa_PRKCA_ST	P16144	ITGB4	P17252	PRKCA	T1297	R1295S	1295	Missense	proximal	-2	no	18.072	14.770	EPSD	COSMIC	16.704	Loss
AGC_PKC_PKCa_PRKCA_ST	P16144	ITGB4	P17252	PRKCA	T1297	N1302S	1302	Missense	distal	5	no	18.072	18.293	EPSD	COSMIC	16.704	Up-regulation
AGC_PKC_PKCa_PRKCA_ST	P16144	ITGB4	P17252	PRKCA	S1360	V1353I	1353	Missense	distal	-7	no	18.940	18.939	PhosphoSitePlus;EPSD	COSMIC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	P16144	ITGB4	P17252	PRKCA	S1360	V1365I	1365	Missense	distal	5	no	18.940	19.027	PhosphoSitePlus;EPSD	COSMIC;GDSC	16.704	Up-regulation
AGC_PKC_PKCa_PRKCA_ST	P16144	ITGB4	P17252	PRKCA	S1364	V1365I	1365	Missense	proximal	1	no	18.268	18.980	EPSD;PhosphoSitePlus	COSMIC;GDSC	16.704	Up-regulation
AGC_PKC_PKCa_PRKCA_ST	P16144	ITGB4	P17252	PRKCA	S1483	V1481M	1481	Missense	proximal	-2	no	16.749	17.610	EPSD	COSMIC	16.704	Up-regulation
AGC_PKC_PKCa_PRKCA_ST	P16144	ITGB4	P17252	PRKCA	S1483	V1477M	1477	Missense	distal	-6	no	16.749	16.860	EPSD	COSMIC	16.704	Up-regulation
AGC_PKC_PKCa_PRKCA_ST	P16144	ITGB4	P17252	PRKCA	S1483	L1488F	1488	Missense	distal	5	no	16.749	16.974	EPSD	COSMIC	16.704	Up-regulation
AGC_PKC_PKCa_PRKCA_ST	P16144	ITGB4	P17252	PRKCA	S1543	P1541S	1541	Missense	proximal	-2	no	18.331	18.071	EPSD	COSMIC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	P16144	ITGB4	P17252	PRKCA	S1543	S1543Y	1543	Missense	central	0	yes	18.331	0.000	EPSD	COSMIC	16.704	Loss
AGC_PKC_PKCa_PRKCA_ST	P16144	ITGB4	P17252	PRKCA	S1547	E1554G	1554	Missense	distal	7	no	17.233	17.304	EPSD	COSMIC	16.704	Up-regulation
AGC_PKC_PKCa_PRKCA_ST	P16144	ITGB4	P17252	PRKCA	S1547	P1541S	1541	Missense	distal	-6	no	17.233	17.264	EPSD	COSMIC	16.704	Up-regulation
AGC_PKC_PKCa_PRKCA_ST	P16144	ITGB4	P17252	PRKCA	S1547	S1543Y	1543	Missense	distal	-4	no	17.233	17.039	EPSD	COSMIC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	P16144	ITGB4	P17252	PRKCA	S1547	R1552L	1552	Missense	distal	5	no	17.233	16.901	EPSD	COSMIC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	P16144	ITGB4	P17252	PRKCA	S1696	E1698K	1698	Missense	proximal	2	no	11.727	17.006	EPSD	COSMIC	16.704	Gain
AGC_PKC_PKCa_PRKCA_ST	P16144	ITGB4	P17252	PRKCA	S1747	H1754Q	1754	Missense	distal	7	no	17.243	17.310	EPSD	COSMIC	16.704	Up-regulation
AGC_PKC_PKCa_PRKCA_ST	Q8NER1	TRPV1	P17252	PRKCA	S5	S6N	6	Missense	proximal	1	no	16.689	16.736	EPSD	COSMIC;GDSC;CCLE	16.704	Gain
AGC_PKC_PKCa_PRKCA_ST	Q8NER1	TRPV1	P17252	PRKCA	S6	S6N	6	Missense	central	0	yes	17.524	0.000	EPSD	COSMIC;GDSC;CCLE	16.704	Loss
AGC_PKC_PKCa_PRKCA_ST	Q8NER1	TRPV1	P17252	PRKCA	S117	F119I	119	Missense	proximal	2	no	18.829	18.100	EPSD	COSMIC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	Q8NER1	TRPV1	P17252	PRKCA	S117	E120K	120	Missense	distal	3	no	18.829	19.445	EPSD	COSMIC	16.704	Up-regulation
AGC_PKC_PKCa_PRKCA_ST	Q8NER1	TRPV1	P17252	PRKCA	S186	R182Q	182	Missense	distal	-4	no	18.027	17.650	EPSD	COSMIC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	Q8NER1	TRPV1	P17252	PRKCA	S186	T184M	184	Missense	proximal	-2	no	18.027	18.940	EPSD	COSMIC	16.704	Up-regulation
AGC_PKC_PKCa_PRKCA_ST	Q8NER1	TRPV1	P17252	PRKCA	S502	M503I	503	Missense	proximal	1	no	23.256	24.307	EPSD;PhosphoSitePlus	COSMIC	16.704	Up-regulation
AGC_PKC_PKCa_PRKCA_ST	Q8NER1	TRPV1	P17252	PRKCA	S502	T505A	505	Missense	distal	3	no	23.256	23.495	EPSD;PhosphoSitePlus	COSMIC	16.704	Up-regulation
AGC_PKC_PKCa_PRKCA_ST	Q8NER1	TRPV1	P17252	PRKCA	S502	F507L	507	Missense	distal	5	no	23.256	23.031	EPSD;PhosphoSitePlus	COSMIC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	Q8NER1	TRPV1	P17252	PRKCA	S502	T505I	505	Missense	distal	3	no	23.256	22.543	EPSD;PhosphoSitePlus	COSMIC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	Q8NER1	TRPV1	P17252	PRKCA	S502	R500W	500	Missense	proximal	-2	no	23.256	21.259	EPSD;PhosphoSitePlus	COSMIC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	Q8NER1	TRPV1	P17252	PRKCA	S775	R772S	772	Missense	distal	-3	no	18.280	15.410	EPSD	COSMIC	16.704	Loss
AGC_PKC_PKCa_PRKCA_ST	Q8NER1	TRPV1	P17252	PRKCA	S775	K771R	771	Missense	distal	-4	no	18.280	18.245	EPSD	COSMIC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	Q8NER1	TRPV1	P17252	PRKCA	S775	G769D	769	Missense	distal	-6	no	18.280	18.230	EPSD	COSMIC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	Q8NER1	TRPV1	P17252	PRKCA	S777	R772S	772	Missense	distal	-5	no	18.563	18.137	EPSD	COSMIC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	Q8NER1	TRPV1	P17252	PRKCA	S777	K771R	771	Missense	distal	-6	no	18.563	18.570	EPSD	COSMIC	16.704	Up-regulation
AGC_PKC_PKCa_PRKCA_ST	Q8NER1	TRPV1	P17252	PRKCA	S801	P795L	795	Missense	distal	-6	no	20.241	20.208	PhosphoSitePlus;EPSD	COSMIC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	Q8NER1	TRPV1	P17252	PRKCA	S821	A827T	827	Missense	distal	6	no	16.924	16.846	EPSD	COSMIC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	P08684	CYP3A4	P17252	PRKCA	S131	E124K	124	Missense	distal	-7	no	19.379	19.387	EPSD;PhosphoSitePlus	COSMIC	16.704	Up-regulation
AGC_PKC_PKCa_PRKCA_ST	P08684	CYP3A4	P17252	PRKCA	S259	T264K	264	Missense	distal	5	no	17.083	17.544	EPSD;PhosphoSitePlus	COSMIC	16.704	Up-regulation
AGC_PKC_PKCa_PRKCA_ST	P08684	CYP3A4	P17252	PRKCA	S259	E262Q	262	Missense	distal	3	no	17.083	15.868	EPSD;PhosphoSitePlus	COSMIC	16.704	Loss
AGC_PKC_PKCa_PRKCA_ST	P08684	CYP3A4	P17252	PRKCA	T264	E262Q	262	Missense	proximal	-2	no	16.001	18.368	EPSD;PhosphoSitePlus	COSMIC	16.704	Gain
AGC_PKC_PKCa_PRKCA_ST	P08684	CYP3A4	P17252	PRKCA	S420	R418K	418	Missense	proximal	-2	no	20.156	18.528	EPSD;PhosphoSitePlus	COSMIC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	P08684	CYP3A4	P17252	PRKCA	S420	P416S	416	Missense	distal	-4	no	20.156	20.327	EPSD;PhosphoSitePlus	COSMIC	16.704	Up-regulation
AGC_PKC_PKCa_PRKCA_ST	P08684	CYP3A4	P17252	PRKCA	S420	E417G	417	Missense	distal	-3	no	20.156	21.832	EPSD;PhosphoSitePlus	COSMIC	16.704	Up-regulation
AGC_PKC_PKCa_PRKCA_ST	P08684	CYP3A4	P17252	PRKCA	S420	D425N	425	Missense	distal	5	no	20.156	20.155	EPSD;PhosphoSitePlus	COSMIC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	P08684	CYP3A4	P17252	PRKCA	S420	K422Q	422	Missense	proximal	2	no	20.156	16.743	EPSD;PhosphoSitePlus	COSMIC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	P08684	CYP3A4	P17252	PRKCA	S420	K422N	422	Missense	proximal	2	no	20.156	15.207	EPSD;PhosphoSitePlus	COSMIC	16.704	Loss
AGC_PKC_PKCa_PRKCA_ST	P08684	CYP3A4	P17252	PRKCA	S464	R458T	458	Missense	distal	-6	no	17.368	17.170	EPSD	COSMIC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	P18031	PTPN1	P17252	PRKCA	S118	G117V	117	Missense	proximal	-1	no	18.699	16.988	EPSD	COSMIC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	P18031	PTPN1	P17252	PRKCA	S118	A122T	122	Missense	distal	4	no	18.699	18.252	EPSD	COSMIC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	P18031	PTPN1	P17252	PRKCA	S118	L119F	119	Missense	proximal	1	no	18.699	19.357	EPSD	COSMIC	16.704	Up-regulation
AGC_PKC_PKCa_PRKCA_ST	P18031	PTPN1	P17252	PRKCA	S352	E349K	349	Missense	distal	-3	no	13.994	16.906	EPSD	COSMIC	16.704	Gain
AGC_PKC_PKCa_PRKCA_ST	P18031	PTPN1	P17252	PRKCA	S363	S365R	365	Missense	proximal	2	no	13.090	17.710	EPSD	COSMIC	16.704	Gain
AGC_PKC_PKCa_PRKCA_ST	P18031	PTPN1	P17252	PRKCA	S378	G377R	377	Missense	proximal	-1	no	21.090	21.229	PhosphoSitePlus	COSMIC	16.704	Up-regulation
AGC_PKC_PKCa_PRKCA_ST	P18031	PTPN1	P17252	PRKCA	S378	R373Q	373	Missense	distal	-5	no	21.090	20.938	PhosphoSitePlus	COSMIC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	P18031	PTPN1	P17252	PRKCA	S378	A385S	385	Missense	distal	7	no	21.090	21.091	PhosphoSitePlus	COSMIC	16.704	Up-regulation
AGC_PKC_PKCa_PRKCA_ST	P18031	PTPN1	P17252	PRKCA	S378	A385V	385	Missense	distal	7	no	21.090	21.035	PhosphoSitePlus	COSMIC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	P18031	PTPN1	P17252	PRKCA	S378	R373L	373	Missense	distal	-5	no	21.090	20.962	PhosphoSitePlus	COSMIC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	P18031	PTPN1	P17252	PRKCA	S378	S372I	372	Missense	distal	-6	no	21.090	20.993	PhosphoSitePlus	COSMIC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	P24844	MYL9	P17252	PRKCA	S2	S2Y	2	Missense	central	0	yes	23.201	0.000	EPSD;PhosphoSitePlus	COSMIC	16.704	Loss
AGC_PKC_PKCa_PRKCA_ST	P24844	MYL9	P17252	PRKCA	S3	S2Y	2	Missense	proximal	-1	no	21.575	21.126	EPSD;PhosphoSitePlus	COSMIC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	P24844	MYL9	P17252	PRKCA	T10	P15S	15	Missense	distal	5	no	22.937	22.778	PhosphoSitePlus;EPSD	COSMIC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	P24844	MYL9	P17252	PRKCA	T10	R14Q	14	Missense	distal	4	no	22.937	22.720	PhosphoSitePlus;EPSD	COSMIC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	P24844	MYL9	P17252	PRKCA	T11	P15S	15	Missense	distal	4	no	20.429	20.629	EPSD	COSMIC	16.704	Up-regulation
AGC_PKC_PKCa_PRKCA_ST	P24844	MYL9	P17252	PRKCA	T11	R14Q	14	Missense	distal	3	no	20.429	17.976	EPSD	COSMIC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	P24844	MYL9	P17252	PRKCA	S20	N21T	21	Missense	proximal	1	no	17.126	17.406	EPSD	COSMIC	16.704	Up-regulation
AGC_PKC_PKCa_PRKCA_ST	P24844	MYL9	P17252	PRKCA	S20	P15S	15	Missense	distal	-5	no	17.126	16.800	EPSD	COSMIC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	P24844	MYL9	P17252	PRKCA	S20	R14Q	14	Missense	distal	-6	no	17.126	16.983	EPSD	COSMIC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	P19174	PLCG1	P17252	PRKCA	S43	R48W	48	Missense	distal	5	no	21.844	21.336	EPSD	COSMIC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	P19174	PLCG1	P17252	PRKCA	S43	E47K	47	Missense	distal	4	no	21.844	22.383	EPSD	COSMIC	16.704	Up-regulation
AGC_PKC_PKCa_PRKCA_ST	P19174	PLCG1	P17252	PRKCA	S705	I704M	704	Missense	proximal	-1	no	17.670	19.613	EPSD	COSMIC	16.704	Up-regulation
AGC_PKC_PKCa_PRKCA_ST	P19174	PLCG1	P17252	PRKCA	S705	R707L	707	Missense	proximal	2	no	17.670	12.684	EPSD	COSMIC	16.704	Loss
AGC_PKC_PKCa_PRKCA_ST	P19174	PLCG1	P17252	PRKCA	S705	S705C	705	Missense	central	0	yes	17.670	0.000	EPSD	COSMIC	16.704	Loss
AGC_PKC_PKCa_PRKCA_ST	P19174	PLCG1	P17252	PRKCA	S1227	P1222S	1222	Missense	distal	-5	no	19.297	18.972	EPSD	COSMIC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	P19174	PLCG1	P17252	PRKCA	S1227	T1226M	1226	Missense	proximal	-1	no	19.297	20.335	EPSD	COSMIC;CCLE	16.704	Up-regulation
AGC_PKC_PKCa_PRKCA_ST	P19174	PLCG1	P17252	PRKCA	S1227	D1234H	1234	Missense	distal	7	no	19.297	19.270	EPSD	COSMIC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	P19174	PLCG1	P17252	PRKCA	S1233	D1234H	1234	Missense	proximal	1	no	16.017	16.803	EPSD	COSMIC	16.704	Gain
AGC_PKC_PKCa_PRKCA_ST	P19174	PLCG1	P17252	PRKCA	S1248	H1241Y	1241	Missense	distal	-7	no	19.739	19.741	PhosphoSitePlus	COSMIC;CCLE	16.704	Up-regulation
AGC_PKC_PKCa_PRKCA_ST	P19174	PLCG1	P17252	PRKCA	S1248	G1247A	1247	Missense	proximal	-1	no	19.739	18.932	PhosphoSitePlus	COSMIC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	P19174	PLCG1	P17252	PRKCA	S1248	A1244T	1244	Missense	distal	-4	no	19.739	18.991	PhosphoSitePlus	COSMIC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	P19174	PLCG1	P17252	PRKCA	S1248	Q1254K	1254	Missense	distal	6	no	19.739	19.850	PhosphoSitePlus	COSMIC	16.704	Up-regulation
AGC_PKC_PKCa_PRKCA_ST	P10636	MAPT	P17252	PRKCA	T167	E165K	165	Missense	proximal	-2	no	15.567	18.066	EPSD	COSMIC	16.704	Gain
AGC_PKC_PKCa_PRKCA_ST	P10636	MAPT	P17252	PRKCA	S171	P175S	175	Missense	distal	4	no	19.508	19.708	EPSD	COSMIC	16.704	Up-regulation
AGC_PKC_PKCa_PRKCA_ST	P10636	MAPT	P17252	PRKCA	S171	A166V	166	Missense	distal	-5	no	19.508	19.424	EPSD	COSMIC;CCLE	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	P10636	MAPT	P17252	PRKCA	S171	E176G	176	Missense	distal	5	no	19.508	19.497	EPSD	COSMIC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	P10636	MAPT	P17252	PRKCA	S171	D177G	177	Missense	distal	6	no	19.508	19.448	EPSD	COSMIC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	P10636	MAPT	P17252	PRKCA	S171	E165K	165	Missense	distal	-6	no	19.508	19.576	EPSD	COSMIC	16.704	Up-regulation
AGC_PKC_PKCa_PRKCA_ST	P10636	MAPT	P17252	PRKCA	S171	G172V	172	Missense	proximal	1	no	19.508	20.239	EPSD	COSMIC	16.704	Up-regulation
AGC_PKC_PKCa_PRKCA_ST	P10636	MAPT	P17252	PRKCA	S341	G343R	343	Missense	proximal	2	no	14.626	19.872	EPSD	COSMIC	16.704	Gain
AGC_PKC_PKCa_PRKCA_ST	P10636	MAPT	P17252	PRKCA	S396	R398C	398	Missense	proximal	2	no	18.925	14.575	EPSD	COSMIC	16.704	Loss
AGC_PKC_PKCa_PRKCA_ST	P10636	MAPT	P17252	PRKCA	S396	S396F	396	Missense	central	0	yes	18.925	0.000	EPSD	COSMIC	16.704	Loss
AGC_PKC_PKCa_PRKCA_ST	P10636	MAPT	P17252	PRKCA	S400	R398C	398	Missense	proximal	-2	no	20.635	18.935	EPSD	COSMIC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	P10636	MAPT	P17252	PRKCA	S400	S396F	396	Missense	distal	-4	no	20.635	20.577	EPSD	COSMIC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	P10636	MAPT	P17252	PRKCA	T403	L410F	410	Missense	distal	7	no	17.027	16.961	EPSD	COSMIC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	P10636	MAPT	P17252	PRKCA	T403	R398C	398	Missense	distal	-5	no	17.027	16.351	EPSD	COSMIC	16.704	Loss
AGC_PKC_PKCa_PRKCA_ST	P10636	MAPT	P17252	PRKCA	T403	S396F	396	Missense	distal	-7	no	17.027	17.019	EPSD	COSMIC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	P10636	MAPT	P17252	PRKCA	S411	L410F	410	Missense	proximal	-1	no	18.586	18.298	EPSD	COSMIC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	P10636	MAPT	P17252	PRKCA	S411	P412S	412	Missense	proximal	1	no	18.586	18.187	EPSD	COSMIC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	P10636	MAPT	P17252	PRKCA	S447	S443Y	443	Missense	distal	-4	no	17.139	16.945	EPSD	COSMIC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	P10636	MAPT	P17252	PRKCA	S447	S447P	447	Missense	central	0	yes	17.139	0.000	EPSD	COSMIC	16.704	Loss
AGC_PKC_PKCa_PRKCA_ST	P10636	MAPT	P17252	PRKCA	S447	R448Q	448	Missense	proximal	1	no	17.139	17.022	EPSD	COSMIC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	P10636	MAPT	P17252	PRKCA	T470	T466M	466	Missense	distal	-4	no	16.965	17.899	EPSD	COSMIC;GDSC;CCLE	16.704	Up-regulation
AGC_PKC_PKCa_PRKCA_ST	P10636	MAPT	P17252	PRKCA	T470	K467T	467	Missense	distal	-3	no	16.965	14.828	EPSD	COSMIC	16.704	Loss
AGC_PKC_PKCa_PRKCA_ST	P10636	MAPT	P17252	PRKCA	T470	P477L	477	Missense	distal	7	no	16.965	16.931	EPSD	COSMIC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	P10636	MAPT	P17252	PRKCA	T470	P477S	477	Missense	distal	7	no	16.965	16.929	EPSD	COSMIC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	P10636	MAPT	P17252	PRKCA	S531	R526H	526	Missense	distal	-5	no	18.059	17.704	EPSD	COSMIC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	P10636	MAPT	P17252	PRKCA	S531	R528S	528	Missense	distal	-3	no	18.059	15.190	EPSD	COSMIC	16.704	Loss
AGC_PKC_PKCa_PRKCA_ST	P10636	MAPT	P17252	PRKCA	S531	P530S	530	Missense	proximal	-1	no	18.059	18.359	EPSD	COSMIC	16.704	Up-regulation
AGC_PKC_PKCa_PRKCA_ST	P10636	MAPT	P17252	PRKCA	S531	P536H	536	Missense	distal	5	no	18.059	17.782	EPSD	COSMIC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	P10636	MAPT	P17252	PRKCA	S531	P535Q	535	Missense	distal	4	no	18.059	18.288	EPSD	COSMIC	16.704	Up-regulation
AGC_PKC_PKCa_PRKCA_ST	P10636	MAPT	P17252	PRKCA	S554	S555F	555	Missense	proximal	1	no	15.259	16.743	EPSD	COSMIC	16.704	Gain
AGC_PKC_PKCa_PRKCA_ST	P10636	MAPT	P17252	PRKCA	S555	P550S	550	Missense	distal	-5	no	19.645	19.320	EPSD	COSMIC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	P10636	MAPT	P17252	PRKCA	S555	R559C	559	Missense	distal	4	no	19.645	18.244	EPSD	COSMIC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	P10636	MAPT	P17252	PRKCA	S555	P553R	553	Missense	proximal	-2	no	19.645	22.687	EPSD	COSMIC	16.704	Up-regulation
AGC_PKC_PKCa_PRKCA_ST	P10636	MAPT	P17252	PRKCA	S555	P553L	553	Missense	proximal	-2	no	19.645	20.000	EPSD	COSMIC	16.704	Up-regulation
AGC_PKC_PKCa_PRKCA_ST	P10636	MAPT	P17252	PRKCA	S555	P549L	549	Missense	distal	-6	no	19.645	19.612	EPSD	COSMIC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	P10636	MAPT	P17252	PRKCA	S555	S555F	555	Missense	central	0	yes	19.645	0.000	EPSD	COSMIC	16.704	Loss
AGC_PKC_PKCa_PRKCA_ST	P10636	MAPT	P17252	PRKCA	S555	P553Q	553	Missense	proximal	-2	no	19.645	20.928	EPSD	COSMIC	16.704	Up-regulation
AGC_PKC_PKCa_PRKCA_ST	P10636	MAPT	P17252	PRKCA	S637	S633N	633	Missense	distal	-4	no	18.000	17.670	EPSD	COSMIC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	P10636	MAPT	P17252	PRKCA	S637	S633I	633	Missense	distal	-4	no	18.000	17.558	EPSD	COSMIC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	P10636	MAPT	P17252	PRKCA	S669	S669L	669	Missense	central	0	yes	19.479	0.000	EPSD	COSMIC	16.704	Loss
AGC_PKC_PKCa_PRKCA_ST	P10636	MAPT	P17252	PRKCA	S669	R666K	666	Missense	distal	-3	no	19.479	17.452	EPSD	COSMIC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	P10636	MAPT	P17252	PRKCA	S669	S673F	673	Missense	distal	4	no	19.479	19.117	EPSD	COSMIC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	P10636	MAPT	P17252	PRKCA	S669	K670N	670	Missense	proximal	1	no	19.479	18.314	EPSD	COSMIC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	P10636	MAPT	P17252	PRKCA	S669	K664N	664	Missense	distal	-5	no	19.479	19.136	EPSD	COSMIC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	P10636	MAPT	P17252	PRKCA	S669	L674Q	674	Missense	distal	5	no	19.479	19.802	EPSD	COSMIC	16.704	Up-regulation
AGC_PKC_PKCa_PRKCA_ST	P10636	MAPT	P17252	PRKCA	T694	R696H	696	Missense	proximal	2	no	18.112	13.088	EPSD	COSMIC	16.704	Loss
AGC_PKC_PKCa_PRKCA_ST	P10636	MAPT	P17252	PRKCA	T694	R696C	696	Missense	proximal	2	no	18.112	13.762	EPSD	COSMIC	16.704	Loss
AGC_PKC_PKCa_PRKCA_ST	P10636	MAPT	P17252	PRKCA	S721	R723W	723	Missense	proximal	2	no	18.782	13.342	EPSD	COSMIC	16.704	Loss
AGC_PKC_PKCa_PRKCA_ST	P10636	MAPT	P17252	PRKCA	S721	V728M	728	Missense	distal	7	no	18.782	18.849	EPSD	COSMIC	16.704	Up-regulation
AGC_PKC_PKCa_PRKCA_ST	P10636	MAPT	P17252	PRKCA	S721	V728A	728	Missense	distal	7	no	18.782	18.837	EPSD	COSMIC	16.704	Up-regulation
AGC_PKC_PKCa_PRKCA_ST	O75689	ADAP1	P17252	PRKCA	S204	R206C	206	Missense	proximal	2	no	16.922	12.572	EPSD	COSMIC	16.704	Loss
AGC_PKC_PKCa_PRKCA_ST	O75689	ADAP1	P17252	PRKCA	S204	S204N	204	Missense	central	0	yes	16.922	0.000	EPSD	COSMIC	16.704	Loss
AGC_PKC_PKCa_PRKCA_ST	O75689	ADAP1	P17252	PRKCA	S204	R206S	206	Missense	proximal	2	no	16.922	12.302	EPSD	COSMIC	16.704	Loss
AGC_PKC_PKCa_PRKCA_ST	O75689	ADAP1	P17252	PRKCA	S204	V197A	197	Missense	distal	-7	no	16.922	16.932	EPSD	COSMIC	16.704	Up-regulation
AGC_PKC_PKCa_PRKCA_ST	O75689	ADAP1	P17252	PRKCA	S204	L200P	200	Missense	distal	-4	no	16.922	17.182	EPSD	COSMIC	16.704	Up-regulation
AGC_PKC_PKCa_PRKCA_ST	P31645	SLC6A4	P17252	PRKCA	S13	L12Q	12	Missense	proximal	-1	no	18.065	18.054	EPSD	COSMIC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	P31645	SLC6A4	P17252	PRKCA	S13	C15S	15	Missense	proximal	2	no	18.065	17.795	EPSD	COSMIC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	P31645	SLC6A4	P17252	PRKCA	S277	G278V	278	Missense	proximal	1	no	17.966	18.697	EPSD;PhosphoSitePlus	COSMIC	16.704	Up-regulation
AGC_PKC_PKCa_PRKCA_ST	P05107	ITGB2	P17252	PRKCA	T118	A112T	112	Missense	distal	-6	no	19.005	18.916	EPSD	COSMIC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	P05107	ITGB2	P17252	PRKCA	S496	S503F	503	Missense	distal	7	no	17.597	17.533	EPSD	COSMIC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	P19086	GNAZ	P17252	PRKCA	S16	R21C	21	Missense	distal	5	no	23.083	22.351	PhosphoSitePlus;EPSD	COSMIC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	P19086	GNAZ	P17252	PRKCA	S16	R17Q	17	Missense	proximal	1	no	23.083	22.966	PhosphoSitePlus;EPSD	COSMIC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	P19086	GNAZ	P17252	PRKCA	S27	R21C	21	Missense	distal	-6	no	21.195	20.825	EPSD;PhosphoSitePlus	COSMIC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	P19086	GNAZ	P17252	PRKCA	S27	R24H	24	Missense	distal	-3	no	21.195	17.338	EPSD;PhosphoSitePlus	COSMIC;GDSC;CCLE	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	O60941	DTNB	P17252	PRKCA	S250	M251T	251	Missense	proximal	1	no	21.054	20.769	EPSD	COSMIC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	O60941	DTNB	P17252	PRKCA	S250	Y256C	256	Missense	distal	6	no	21.054	20.867	EPSD	COSMIC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	O60941	DTNB	P17252	PRKCA	S250	R255W	255	Missense	distal	5	no	21.054	20.546	EPSD	COSMIC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	O60941	DTNB	P17252	PRKCA	S290	E288K	288	Missense	proximal	-2	no	14.506	17.005	EPSD	COSMIC	16.704	Gain
AGC_PKC_PKCa_PRKCA_ST	O60941	DTNB	P17252	PRKCA	S291	E288K	288	Missense	distal	-3	no	15.604	18.517	EPSD	COSMIC	16.704	Gain
AGC_PKC_PKCa_PRKCA_ST	O60941	DTNB	P17252	PRKCA	S497	A498S	498	Missense	proximal	1	no	16.796	15.998	EPSD	COSMIC	16.704	Loss
AGC_PKC_PKCa_PRKCA_ST	O60941	DTNB	P17252	PRKCA	S497	R504W	504	Missense	distal	7	no	16.796	16.616	EPSD	COSMIC	16.704	Loss
AGC_PKC_PKCa_PRKCA_ST	O60941	DTNB	P17252	PRKCA	S497	A498T	498	Missense	proximal	1	no	16.796	16.325	EPSD	COSMIC	16.704	Loss
AGC_PKC_PKCa_PRKCA_ST	O60941	DTNB	P17252	PRKCA	S502	A498S	498	Missense	distal	-4	no	18.707	18.620	EPSD	COSMIC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	O60941	DTNB	P17252	PRKCA	S502	R504W	504	Missense	proximal	2	no	18.707	13.267	EPSD	COSMIC	16.704	Loss
AGC_PKC_PKCa_PRKCA_ST	O60941	DTNB	P17252	PRKCA	S502	A498T	498	Missense	distal	-4	no	18.707	17.958	EPSD	COSMIC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	O60941	DTNB	P17252	PRKCA	S502	M507V	507	Missense	distal	5	no	18.707	18.299	EPSD	COSMIC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	O60941	DTNB	P17252	PRKCA	S502	V508M	508	Missense	distal	6	no	18.707	18.795	EPSD	COSMIC	16.704	Up-regulation
AGC_PKC_PKCa_PRKCA_ST	O60941	DTNB	P17252	PRKCA	T580	R585C	585	Missense	distal	5	no	17.204	16.472	EPSD	COSMIC	16.704	Loss
AGC_PKC_PKCa_PRKCA_ST	O60941	DTNB	P17252	PRKCA	T580	R582K	582	Missense	proximal	2	no	17.204	16.782	EPSD	COSMIC;GDSC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	O60941	DTNB	P17252	PRKCA	T580	E574K	574	Missense	distal	-6	no	17.204	17.271	EPSD	COSMIC	16.704	Up-regulation
AGC_PKC_PKCa_PRKCA_ST	Q9UKG1	APPL1	P17252	PRKCA	S410	A415T	415	Missense	distal	5	no	21.037	20.758	EPSD	COSMIC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	Q9UKG1	APPL1	P17252	PRKCA	S410	R412W	412	Missense	proximal	2	no	21.037	15.597	EPSD	COSMIC	16.704	Loss
AGC_PKC_PKCa_PRKCA_ST	Q9UKG1	APPL1	P17252	PRKCA	S410	Q417H	417	Missense	distal	7	no	21.037	20.970	EPSD	COSMIC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	Q9UKG1	APPL1	P17252	PRKCA	T422	A415T	415	Missense	distal	-7	no	18.435	18.431	EPSD	COSMIC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	Q9UKG1	APPL1	P17252	PRKCA	T422	Q417H	417	Missense	distal	-5	no	18.435	18.232	EPSD	COSMIC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	Q9UKG1	APPL1	P17252	PRKCA	S485	G487R	487	Missense	proximal	2	no	14.962	20.207	EPSD	COSMIC	16.704	Gain
AGC_PKC_PKCa_PRKCA_ST	Q9UKG1	APPL1	P17252	PRKCA	S488	P481L	481	Missense	distal	-7	no	18.651	18.648	EPSD	COSMIC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	Q9UKG1	APPL1	P17252	PRKCA	S488	G487V	487	Missense	proximal	-1	no	18.651	16.940	EPSD	COSMIC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	Q9UKG1	APPL1	P17252	PRKCA	S488	G487R	487	Missense	proximal	-1	no	18.651	18.790	EPSD	COSMIC	16.704	Up-regulation
AGC_PKC_PKCa_PRKCA_ST	Q9UKG1	APPL1	P17252	PRKCA	S488	S491F	491	Missense	distal	3	no	18.651	18.138	EPSD	COSMIC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	Q9UKG1	APPL1	P17252	PRKCA	S488	E492K	492	Missense	distal	4	no	18.651	19.190	EPSD	COSMIC	16.704	Up-regulation
AGC_PKC_PKCa_PRKCA_ST	Q9UKG1	APPL1	P17252	PRKCA	S591	G593R	593	Missense	proximal	2	no	15.307	20.552	EPSD	COSMIC	16.704	Gain
AGC_PKC_PKCa_PRKCA_ST	Q9UKG1	APPL1	P17252	PRKCA	S592	G593R	593	Missense	proximal	1	no	21.410	22.364	EPSD	COSMIC	16.704	Up-regulation
AGC_PKC_PKCa_PRKCA_ST	Q9UKG1	APPL1	P17252	PRKCA	S595	G593R	593	Missense	proximal	-2	no	14.470	17.342	EPSD	COSMIC	16.704	Gain
AGC_PKC_PKCa_PRKCA_ST	Q9UKG1	APPL1	P17252	PRKCA	S597	G593R	593	Missense	distal	-4	no	17.031	17.133	EPSD	COSMIC	16.704	Up-regulation
AGC_PKC_PKCa_PRKCA_ST	Q9UKG1	APPL1	P17252	PRKCA	S636	E643Q	643	Missense	distal	7	no	22.058	22.149	EPSD	COSMIC;GDSC;CCLE	16.704	Up-regulation
AGC_PKC_PKCa_PRKCA_ST	P04626	ERBB2	P17252	PRKCA	T686	R683G	683	Missense	distal	-3	no	21.608	18.347	PhosphoSitePlus	COSMIC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	P04626	ERBB2	P17252	PRKCA	T686	R683Q	683	Missense	distal	-3	no	21.608	18.751	PhosphoSitePlus	COSMIC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	P04626	ERBB2	P17252	PRKCA	T686	R688W	688	Missense	proximal	2	no	21.608	16.169	PhosphoSitePlus	COSMIC	16.704	Loss
AGC_PKC_PKCa_PRKCA_ST	P04626	ERBB2	P17252	PRKCA	T686	Q680H	680	Missense	distal	-6	no	21.608	21.684	PhosphoSitePlus	COSMIC	16.704	Up-regulation
AGC_PKC_PKCa_PRKCA_ST	P04626	ERBB2	P17252	PRKCA	T686	Q679L	679	Missense	distal	-7	no	21.608	21.606	PhosphoSitePlus	COSMIC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	P04626	ERBB2	P17252	PRKCA	T686	E693K	693	Missense	distal	7	no	21.608	21.754	PhosphoSitePlus	COSMIC	16.704	Up-regulation
AGC_PKC_PKCa_PRKCA_ST	P04626	ERBB2	P17252	PRKCA	T686	T686R	686	Missense	central	0	yes	21.608	0.000	PhosphoSitePlus	COSMIC;CCLE	16.704	Loss
AGC_PKC_PKCa_PRKCA_ST	P04626	ERBB2	P17252	PRKCA	T686	L690P	690	Missense	distal	4	no	21.608	22.201	PhosphoSitePlus	COSMIC	16.704	Up-regulation
AGC_PKC_PKCa_PRKCA_ST	P04626	ERBB2	P17252	PRKCA	T686	R683W	683	Missense	distal	-3	no	21.608	19.255	PhosphoSitePlus	COSMIC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	P04626	ERBB2	P17252	PRKCA	S760	V754M	754	Missense	distal	-6	no	17.279	17.390	EPSD	COSMIC	16.704	Up-regulation
AGC_PKC_PKCa_PRKCA_ST	P04626	ERBB2	P17252	PRKCA	S760	L755A	755	Missense	distal	-5	no	17.279	16.927	EPSD	COSMIC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	P04626	ERBB2	P17252	PRKCA	S760	L755P	755	Missense	distal	-5	no	17.279	17.305	EPSD	COSMIC	16.704	Up-regulation
AGC_PKC_PKCa_PRKCA_ST	P04626	ERBB2	P17252	PRKCA	S760	S760F	760	Missense	central	0	yes	17.279	0.000	EPSD	COSMIC	16.704	Loss
AGC_PKC_PKCa_PRKCA_ST	P04626	ERBB2	P17252	PRKCA	S760	E757K	757	Missense	distal	-3	no	17.279	20.191	EPSD	COSMIC	16.704	Up-regulation
AGC_PKC_PKCa_PRKCA_ST	P04626	ERBB2	P17252	PRKCA	S760	E757D	757	Missense	distal	-3	no	17.279	17.176	EPSD	COSMIC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	P04626	ERBB2	P17252	PRKCA	S760	S760P	760	Missense	central	0	yes	17.279	0.000	EPSD	COSMIC	16.704	Loss
AGC_PKC_PKCa_PRKCA_ST	P04626	ERBB2	P17252	PRKCA	S760	P761L	761	Missense	proximal	1	no	17.279	17.706	EPSD	COSMIC	16.704	Up-regulation
AGC_PKC_PKCa_PRKCA_ST	P04626	ERBB2	P17252	PRKCA	S760	L755R	755	Missense	distal	-5	no	17.279	17.407	EPSD	COSMIC	16.704	Up-regulation
AGC_PKC_PKCa_PRKCA_ST	P04626	ERBB2	P17252	PRKCA	S760	L755F	755	Missense	distal	-5	no	17.279	17.083	EPSD	COSMIC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	P04626	ERBB2	P17252	PRKCA	S783	L785R	785	Missense	proximal	2	no	12.105	17.092	EPSD	COSMIC	16.704	Gain
AGC_PKC_PKCa_PRKCA_ST	P04626	ERBB2	P17252	PRKCA	S819	R816C	816	Missense	distal	-3	no	17.197	14.457	EPSD	COSMIC	16.704	Loss
AGC_PKC_PKCa_PRKCA_ST	P04626	ERBB2	P17252	PRKCA	S819	S819F	819	Missense	central	0	yes	17.197	0.000	EPSD	COSMIC	16.704	Loss
AGC_PKC_PKCa_PRKCA_ST	P04626	ERBB2	P17252	PRKCA	S819	G815R	815	Missense	distal	-4	no	17.197	17.298	EPSD	COSMIC	16.704	Up-regulation
AGC_PKC_PKCa_PRKCA_ST	P04626	ERBB2	P17252	PRKCA	S819	N813I	813	Missense	distal	-6	no	17.197	17.157	EPSD	COSMIC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	P04626	ERBB2	P17252	PRKCA	S819	D821Y	821	Missense	proximal	2	no	17.197	17.980	EPSD	COSMIC	16.704	Up-regulation
AGC_PKC_PKCa_PRKCA_ST	P04626	ERBB2	P17252	PRKCA	S819	R814C	814	Missense	distal	-5	no	17.197	16.521	EPSD	COSMIC	16.704	Loss
AGC_PKC_PKCa_PRKCA_ST	P04626	ERBB2	P17252	PRKCA	S819	R816H	816	Missense	distal	-3	no	17.197	13.340	EPSD	COSMIC;GDSC;CCLE	16.704	Loss
AGC_PKC_PKCa_PRKCA_ST	P04626	ERBB2	P17252	PRKCA	S819	S819P	819	Missense	central	0	yes	17.197	0.000	EPSD	COSMIC	16.704	Loss
AGC_PKC_PKCa_PRKCA_ST	P04626	ERBB2	P17252	PRKCA	T900	F899L	899	Missense	proximal	-1	no	16.654	16.942	EPSD	COSMIC	16.704	Gain
AGC_PKC_PKCa_PRKCA_ST	P04626	ERBB2	P17252	PRKCA	S1050	S1049I	1049	Missense	proximal	-1	no	16.820	15.537	EPSD	COSMIC	16.704	Loss
AGC_PKC_PKCa_PRKCA_ST	P04626	ERBB2	P17252	PRKCA	S1050	S1051F	1051	Missense	proximal	1	no	16.820	18.304	EPSD	COSMIC	16.704	Up-regulation
AGC_PKC_PKCa_PRKCA_ST	P04626	ERBB2	P17252	PRKCA	S1050	S1050L	1050	Missense	central	0	yes	16.820	0.000	EPSD	COSMIC;GDSC	16.704	Loss
AGC_PKC_PKCa_PRKCA_ST	P04626	ERBB2	P17252	PRKCA	S1050	G1056S	1056	Missense	distal	6	no	16.820	16.899	EPSD	COSMIC	16.704	Up-regulation
AGC_PKC_PKCa_PRKCA_ST	P04626	ERBB2	P17252	PRKCA	S1050	G1056D	1056	Missense	distal	6	no	16.820	16.880	EPSD	COSMIC	16.704	Up-regulation
AGC_PKC_PKCa_PRKCA_ST	P04626	ERBB2	P17252	PRKCA	S1050	G1056C	1056	Missense	distal	6	no	16.820	16.731	EPSD	COSMIC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	P04626	ERBB2	P17252	PRKCA	S1051	S1049I	1049	Missense	proximal	-2	no	21.659	21.373	EPSD	COSMIC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	P04626	ERBB2	P17252	PRKCA	S1051	S1051F	1051	Missense	central	0	yes	21.659	0.000	EPSD	COSMIC	16.704	Loss
AGC_PKC_PKCa_PRKCA_ST	P04626	ERBB2	P17252	PRKCA	S1051	S1050L	1050	Missense	proximal	-1	no	21.659	21.240	EPSD	COSMIC;GDSC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	P04626	ERBB2	P17252	PRKCA	S1051	D1058A	1058	Missense	distal	7	no	21.659	21.655	EPSD	COSMIC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	P04626	ERBB2	P17252	PRKCA	S1051	D1058N	1058	Missense	distal	7	no	21.659	21.633	EPSD	COSMIC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	P04626	ERBB2	P17252	PRKCA	S1051	G1056S	1056	Missense	distal	5	no	21.659	21.799	EPSD	COSMIC	16.704	Up-regulation
AGC_PKC_PKCa_PRKCA_ST	P04626	ERBB2	P17252	PRKCA	S1051	G1056D	1056	Missense	distal	5	no	21.659	21.579	EPSD	COSMIC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	P04626	ERBB2	P17252	PRKCA	S1051	G1056C	1056	Missense	distal	5	no	21.659	21.209	EPSD	COSMIC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	P04626	ERBB2	P17252	PRKCA	S1151	D1144N	1144	Missense	distal	-7	no	19.955	19.954	EPSD	COSMIC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	P04626	ERBB2	P17252	PRKCA	S1151	P1156H	1156	Missense	distal	5	no	19.955	19.678	EPSD	COSMIC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	P04626	ERBB2	P17252	PRKCA	S1151	R1146W	1146	Missense	distal	-5	no	19.955	19.641	EPSD	COSMIC;GDSC;CCLE	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	P04626	ERBB2	P17252	PRKCA	S1151	R1153L	1153	Missense	proximal	2	no	19.955	14.968	EPSD	COSMIC	16.704	Loss
AGC_PKC_PKCa_PRKCA_ST	P04626	ERBB2	P17252	PRKCA	S1151	D1144H	1144	Missense	distal	-7	no	19.955	19.957	EPSD	COSMIC;GDSC	16.704	Up-regulation
AGC_PKC_PKCa_PRKCA_ST	P04626	ERBB2	P17252	PRKCA	S1151	P1147S	1147	Missense	distal	-4	no	19.955	20.126	EPSD	COSMIC	16.704	Up-regulation
AGC_PKC_PKCa_PRKCA_ST	P04626	ERBB2	P17252	PRKCA	S1151	S1151L	1151	Missense	central	0	yes	19.955	0.000	EPSD	COSMIC	16.704	Loss
AGC_PKC_PKCa_PRKCA_ST	P04626	ERBB2	P17252	PRKCA	T1172	P1175R	1175	Missense	distal	3	no	16.048	17.579	EPSD	COSMIC	16.704	Gain
AGC_PKC_PKCa_PRKCA_ST	O14493	CLDN4	P17252	PRKCA	S194	R201G	201	Missense	distal	7	no	17.231	17.207	PhosphoSitePlus	COSMIC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	P08253	MMP2	P17252	PRKCA	S160	R161G	161	Missense	proximal	1	no	16.872	15.919	EPSD;PhosphoSitePlus	COSMIC;CCLE	16.704	Loss
AGC_PKC_PKCa_PRKCA_ST	P08253	MMP2	P17252	PRKCA	S160	T155S	155	Missense	distal	-5	no	16.872	16.544	EPSD;PhosphoSitePlus	COSMIC	16.704	Loss
AGC_PKC_PKCa_PRKCA_ST	P08253	MMP2	P17252	PRKCA	S160	E166V	166	Missense	distal	6	no	16.872	16.818	EPSD;PhosphoSitePlus	COSMIC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	P08253	MMP2	P17252	PRKCA	T250	N245S	245	Missense	distal	-5	no	17.291	17.220	EPSD;PhosphoSitePlus	COSMIC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	P08253	MMP2	P17252	PRKCA	T250	T250A	250	Missense	central	0	yes	17.291	0.000	EPSD;PhosphoSitePlus	COSMIC	16.704	Loss
AGC_PKC_PKCa_PRKCA_ST	P08253	MMP2	P17252	PRKCA	S365	G371R	371	Missense	distal	6	no	17.149	17.299	EPSD;PhosphoSitePlus	COSMIC	16.704	Up-regulation
AGC_PKC_PKCa_PRKCA_ST	P08253	MMP2	P17252	PRKCA	S365	G367D	367	Missense	proximal	2	no	17.149	17.116	EPSD;PhosphoSitePlus	COSMIC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	P08253	MMP2	P17252	PRKCA	S365	S362N	362	Missense	distal	-3	no	17.149	15.793	EPSD;PhosphoSitePlus	COSMIC	16.704	Loss
AGC_PKC_PKCa_PRKCA_ST	P08253	MMP2	P17252	PRKCA	S365	G367V	367	Missense	proximal	2	no	17.149	17.381	EPSD;PhosphoSitePlus	COSMIC	16.704	Up-regulation
AGC_PKC_PKCa_PRKCA_ST	P08253	MMP2	P17252	PRKCA	S369	G371R	371	Missense	proximal	2	no	12.572	17.817	EPSD	COSMIC	16.704	Gain
AGC_PKC_PKCa_PRKCA_ST	P08253	MMP2	P17252	PRKCA	T377	N380H	380	Missense	distal	3	no	16.493	17.351	EPSD;PhosphoSitePlus	COSMIC;GDSC;CCLE	16.704	Gain
AGC_PKC_PKCa_PRKCA_ST	Q9H3Q1	CDC42EP4	P17252	PRKCA	S14	R19G	19	Missense	distal	5	no	25.078	24.797	EPSD	COSMIC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	Q9H3Q1	CDC42EP4	P17252	PRKCA	S18	R19G	19	Missense	proximal	1	no	19.773	18.820	PhosphoSitePlus;EPSD	COSMIC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	Q9H3Q1	CDC42EP4	P17252	PRKCA	S73	K75N	75	Missense	proximal	2	no	20.992	16.043	EPSD	COSMIC	16.704	Loss
AGC_PKC_PKCa_PRKCA_ST	Q9H3Q1	CDC42EP4	P17252	PRKCA	S74	K75N	75	Missense	proximal	1	no	19.377	18.212	EPSD	COSMIC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	Q9H3Q1	CDC42EP4	P17252	PRKCA	S77	K75N	75	Missense	proximal	-2	no	18.331	16.763	EPSD	COSMIC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	Q9H3Q1	CDC42EP4	P17252	PRKCA	S80	K75N	75	Missense	distal	-5	no	20.408	20.065	EPSD;PhosphoSitePlus	COSMIC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	Q9H3Q1	CDC42EP4	P17252	PRKCA	S89	E96K	96	Missense	distal	7	no	18.491	18.637	EPSD	COSMIC	16.704	Up-regulation
AGC_PKC_PKCa_PRKCA_ST	Q9H3Q1	CDC42EP4	P17252	PRKCA	S91	E96K	96	Missense	distal	5	no	17.474	17.888	EPSD	COSMIC	16.704	Up-regulation
AGC_PKC_PKCa_PRKCA_ST	Q9H3Q1	CDC42EP4	P17252	PRKCA	S91	R97W	97	Missense	distal	6	no	17.474	17.227	EPSD	COSMIC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	Q9H3Q1	CDC42EP4	P17252	PRKCA	S105	A110S	110	Missense	distal	5	no	19.370	19.266	EPSD	COSMIC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	Q9H3Q1	CDC42EP4	P17252	PRKCA	S105	S105F	105	Missense	central	0	yes	19.370	0.000	EPSD	COSMIC	16.704	Loss
AGC_PKC_PKCa_PRKCA_ST	Q9H3Q1	CDC42EP4	P17252	PRKCA	S295	S292I	292	Missense	distal	-3	no	18.309	16.692	EPSD	COSMIC;CCLE	16.704	Loss
AGC_PKC_PKCa_PRKCA_ST	Q07954	LRP1	P17252	PRKCA	S1878	R1880W	1880	Missense	proximal	2	no	17.142	11.702	EPSD	COSMIC;GDSC;CCLE	16.704	Loss
AGC_PKC_PKCa_PRKCA_ST	Q07954	LRP1	P17252	PRKCA	S1997	R1999C	1999	Missense	proximal	2	no	16.987	12.637	EPSD	COSMIC	16.704	Loss
AGC_PKC_PKCa_PRKCA_ST	Q07954	LRP1	P17252	PRKCA	S2563	S2559P	2559	Missense	distal	-4	no	19.367	19.195	EPSD	COSMIC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	Q07954	LRP1	P17252	PRKCA	S2563	S2563F	2563	Missense	central	0	yes	19.367	0.000	EPSD	COSMIC	16.704	Loss
AGC_PKC_PKCa_PRKCA_ST	Q07954	LRP1	P17252	PRKCA	S2621	G2619R	2619	Missense	proximal	-2	no	14.792	17.664	EPSD	COSMIC	16.704	Gain
AGC_PKC_PKCa_PRKCA_ST	Q07954	LRP1	P17252	PRKCA	S2950	L2945V	2945	Missense	distal	-5	no	16.788	16.351	EPSD	COSMIC	16.704	Loss
AGC_PKC_PKCa_PRKCA_ST	Q07954	LRP1	P17252	PRKCA	S3938	A3932T	3932	Missense	distal	-6	no	19.086	18.997	EPSD	COSMIC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	Q07954	LRP1	P17252	PRKCA	S4071	I4072L	4072	Missense	proximal	1	no	18.278	17.442	EPSD	COSMIC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	Q07954	LRP1	P17252	PRKCA	S4071	A4064D	4064	Missense	distal	-7	no	18.278	18.272	EPSD	COSMIC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	Q07954	LRP1	P17252	PRKCA	S4071	A4064T	4064	Missense	distal	-7	no	18.278	18.273	EPSD	COSMIC;GDSC;CCLE	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	Q07954	LRP1	P17252	PRKCA	T4460	N4461I	4461	Missense	proximal	1	no	16.438	18.054	EPSD;PhosphoSitePlus	COSMIC	16.704	Gain
AGC_PKC_PKCa_PRKCA_ST	P52565	ARHGDIA	P17252	PRKCA	S47	E40K	40	Missense	distal	-7	no	17.169	17.176	EPSD	COSMIC	16.704	Up-regulation
AGC_PKC_PKCa_PRKCA_ST	P52565	ARHGDIA	P17252	PRKCA	S47	E40Q	40	Missense	distal	-7	no	17.169	17.173	EPSD	COSMIC	16.704	Up-regulation
AGC_PKC_PKCa_PRKCA_ST	P52565	ARHGDIA	P17252	PRKCA	T132	R134S	134	Missense	proximal	2	no	17.698	13.078	EPSD	COSMIC	16.704	Loss
AGC_PKC_PKCa_PRKCA_ST	P52565	ARHGDIA	P17252	PRKCA	T132	G136C	136	Missense	distal	4	no	17.698	16.900	EPSD	COSMIC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	P52565	ARHGDIA	P17252	PRKCA	T132	V137F	137	Missense	distal	5	no	17.698	18.012	EPSD	COSMIC	16.704	Up-regulation
AGC_PKC_PKCa_PRKCA_ST	P52565	ARHGDIA	P17252	PRKCA	T132	V137I	137	Missense	distal	5	no	17.698	17.785	EPSD	COSMIC	16.704	Up-regulation
AGC_PKC_PKCa_PRKCA_ST	P52565	ARHGDIA	P17252	PRKCA	S176	S179A	179	Missense	distal	3	no	17.490	17.284	EPSD	COSMIC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	P52565	ARHGDIA	P17252	PRKCA	S176	T182I	182	Missense	distal	6	no	17.490	17.504	EPSD	COSMIC	16.704	Up-regulation
AGC_PKC_PKCa_PRKCA_ST	P52565	ARHGDIA	P17252	PRKCA	S176	R172W	172	Missense	distal	-4	no	17.490	16.664	EPSD	COSMIC	16.704	Loss
AGC_PKC_PKCa_PRKCA_ST	P52565	ARHGDIA	P17252	PRKCA	S176	M169L	169	Missense	distal	-7	no	17.490	17.482	EPSD	COSMIC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	P52565	ARHGDIA	P17252	PRKCA	S176	T182R	182	Missense	distal	6	no	17.490	17.610	EPSD	COSMIC	16.704	Up-regulation
AGC_PKC_PKCa_PRKCA_ST	P53004	BLVRA	P17252	PRKCA	S21	S21F	21	Missense	central	0	yes	24.825	0.000	EPSD	COSMIC	16.704	Loss
AGC_PKC_PKCa_PRKCA_ST	P53004	BLVRA	P17252	PRKCA	S230	R225Q	225	Missense	distal	-5	no	19.508	19.356	PhosphoSitePlus;EPSD	COSMIC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	P53004	BLVRA	P17252	PRKCA	S230	S235Y	235	Missense	distal	5	no	19.508	19.535	PhosphoSitePlus;EPSD	COSMIC	16.704	Up-regulation
AGC_PKC_PKCa_PRKCA_ST	P53004	BLVRA	P17252	PRKCA	S230	R227K	227	Missense	distal	-3	no	19.508	17.482	PhosphoSitePlus;EPSD	COSMIC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	P19429	TNNI3	P17252	PRKCA	S23	R27H	27	Missense	distal	4	no	20.612	20.329	EPSD;PhosphoSitePlus	COSMIC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	P19429	TNNI3	P17252	PRKCA	S23	S23P	23	Missense	central	0	yes	20.612	0.000	EPSD;PhosphoSitePlus	COSMIC	16.704	Loss
AGC_PKC_PKCa_PRKCA_ST	P19429	TNNI3	P17252	PRKCA	S24	R27H	27	Missense	distal	3	no	23.700	22.988	EPSD;PhosphoSitePlus	COSMIC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	P19429	TNNI3	P17252	PRKCA	S24	S23P	23	Missense	proximal	-1	no	23.700	23.400	EPSD;PhosphoSitePlus	COSMIC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	P19429	TNNI3	P17252	PRKCA	S39	H34Q	34	Missense	distal	-5	no	19.795	19.998	EPSD	COSMIC	16.704	Up-regulation
AGC_PKC_PKCa_PRKCA_ST	P19429	TNNI3	P17252	PRKCA	S39	E32A	32	Missense	distal	-7	no	19.795	19.804	EPSD	COSMIC	16.704	Up-regulation
AGC_PKC_PKCa_PRKCA_ST	P19429	TNNI3	P17252	PRKCA	S39	K37T	37	Missense	proximal	-2	no	19.795	18.528	EPSD	COSMIC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	P19429	TNNI3	P17252	PRKCA	S42	K37T	37	Missense	distal	-5	no	19.146	19.060	EPSD;PhosphoSitePlus	COSMIC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	P19429	TNNI3	P17252	PRKCA	S44	K37T	37	Missense	distal	-7	no	17.602	17.599	EPSD;PhosphoSitePlus	COSMIC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	P19429	TNNI3	P17252	PRKCA	S77	Q81H	81	Missense	distal	4	no	21.044	20.979	EPSD	COSMIC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	P19429	TNNI3	P17252	PRKCA	S77	A75S	75	Missense	proximal	-2	no	21.044	20.828	EPSD	COSMIC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	P19429	TNNI3	P17252	PRKCA	S77	G73W	73	Missense	distal	-4	no	21.044	20.320	EPSD	COSMIC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	P19429	TNNI3	P17252	PRKCA	S77	P82S	82	Missense	distal	5	no	21.044	20.885	EPSD	COSMIC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	P19429	TNNI3	P17252	PRKCA	T143	R141Q	141	Missense	proximal	-2	no	21.018	19.259	EPSD;PhosphoSitePlus	COSMIC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	P19429	TNNI3	P17252	PRKCA	T143	R146I	146	Missense	distal	3	no	21.018	18.468	EPSD;PhosphoSitePlus	COSMIC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	P08183	ABCB1	P17252	PRKCA	S23	N21D	21	Missense	proximal	-2	no	19.118	18.896	EPSD	COSMIC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	P08183	ABCB1	P17252	PRKCA	S23	K18T	18	Missense	distal	-5	no	19.118	19.032	EPSD	COSMIC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	P08183	ABCB1	P17252	PRKCA	S23	K25Q	25	Missense	proximal	2	no	19.118	15.705	EPSD	COSMIC;GDSC;CCLE	16.704	Loss
AGC_PKC_PKCa_PRKCA_ST	P08183	ABCB1	P17252	PRKCA	S35	V36I	36	Missense	proximal	1	no	16.230	16.941	EPSD	COSMIC	16.704	Gain
AGC_PKC_PKCa_PRKCA_ST	P08183	ABCB1	P17252	PRKCA	T591	R588C	588	Missense	distal	-3	no	19.388	16.649	EPSD	COSMIC	16.704	Loss
AGC_PKC_PKCa_PRKCA_ST	P08183	ABCB1	P17252	PRKCA	T591	R593H	593	Missense	proximal	2	no	19.388	14.365	EPSD	COSMIC	16.704	Loss
AGC_PKC_PKCa_PRKCA_ST	P08183	ABCB1	P17252	PRKCA	T591	D596H	596	Missense	distal	5	no	19.388	19.491	EPSD	COSMIC	16.704	Up-regulation
AGC_PKC_PKCa_PRKCA_ST	P08183	ABCB1	P17252	PRKCA	T591	R588H	588	Missense	distal	-3	no	19.388	15.532	EPSD	COSMIC	16.704	Loss
AGC_PKC_PKCa_PRKCA_ST	P08183	ABCB1	P17252	PRKCA	S661	R664G	664	Missense	distal	3	no	20.128	19.489	PhosphoSitePlus;EPSD	COSMIC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	P08183	ABCB1	P17252	PRKCA	S661	K665R	665	Missense	distal	4	no	20.128	19.957	PhosphoSitePlus;EPSD	COSMIC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	P08183	ABCB1	P17252	PRKCA	S661	S660C	660	Missense	proximal	-1	no	20.128	17.856	PhosphoSitePlus;EPSD	COSMIC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	P08183	ABCB1	P17252	PRKCA	S661	S667T	667	Missense	distal	6	no	20.128	20.080	PhosphoSitePlus;EPSD	COSMIC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	P08183	ABCB1	P17252	PRKCA	S667	R664G	664	Missense	distal	-3	no	24.429	21.168	EPSD;PhosphoSitePlus	COSMIC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	P08183	ABCB1	P17252	PRKCA	S667	K665R	665	Missense	proximal	-2	no	24.429	26.057	EPSD;PhosphoSitePlus	COSMIC	16.704	Up-regulation
AGC_PKC_PKCa_PRKCA_ST	P08183	ABCB1	P17252	PRKCA	S667	S660C	660	Missense	distal	-7	no	24.429	24.415	EPSD;PhosphoSitePlus	COSMIC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	P08183	ABCB1	P17252	PRKCA	S667	R669G	669	Missense	proximal	2	no	24.429	19.184	EPSD;PhosphoSitePlus	COSMIC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	P08183	ABCB1	P17252	PRKCA	S667	G674E	674	Missense	distal	7	no	24.429	24.358	EPSD;PhosphoSitePlus	COSMIC;GDSC;CCLE	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	P08183	ABCB1	P17252	PRKCA	S671	A677T	677	Missense	distal	6	no	22.872	22.794	EPSD;PhosphoSitePlus	COSMIC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	P08183	ABCB1	P17252	PRKCA	S671	R664G	664	Missense	distal	-7	no	22.872	22.863	EPSD;PhosphoSitePlus	COSMIC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	P08183	ABCB1	P17252	PRKCA	S671	K665R	665	Missense	distal	-6	no	22.872	22.879	EPSD;PhosphoSitePlus	COSMIC	16.704	Up-regulation
AGC_PKC_PKCa_PRKCA_ST	P08183	ABCB1	P17252	PRKCA	S671	R669G	669	Missense	proximal	-2	no	22.872	20.000	EPSD;PhosphoSitePlus	COSMIC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	P08183	ABCB1	P17252	PRKCA	S671	G674E	674	Missense	distal	3	no	22.872	22.274	EPSD;PhosphoSitePlus	COSMIC;GDSC;CCLE	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	P08183	ABCB1	P17252	PRKCA	S671	S667T	667	Missense	distal	-4	no	22.872	22.211	EPSD;PhosphoSitePlus	COSMIC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	P08183	ABCB1	P17252	PRKCA	S675	A677T	677	Missense	proximal	2	no	18.840	18.728	EPSD	COSMIC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	P08183	ABCB1	P17252	PRKCA	S675	R669G	669	Missense	distal	-6	no	18.840	18.733	EPSD	COSMIC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	P08183	ABCB1	P17252	PRKCA	S675	G674E	674	Missense	proximal	-1	no	18.840	18.610	EPSD	COSMIC;GDSC;CCLE	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	P08183	ABCB1	P17252	PRKCA	S683	A677T	677	Missense	distal	-6	no	22.617	22.528	EPSD	COSMIC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	P08183	ABCB1	P17252	PRKCA	S683	K685E	685	Missense	proximal	2	no	22.617	17.338	EPSD	COSMIC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	P08183	ABCB1	P17252	PRKCA	S683	E686D	686	Missense	distal	3	no	22.617	22.130	EPSD	COSMIC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	O14745	SLC9A3R1	P17252	PRKCA	S77	V75L	75	Missense	proximal	-2	no	16.912	17.066	EPSD;PhosphoSitePlus	COSMIC	16.704	Up-regulation
AGC_PKC_PKCa_PRKCA_ST	O14745	SLC9A3R1	P17252	PRKCA	S162	N167I	167	Missense	distal	5	no	16.747	16.774	EPSD;PhosphoSitePlus	COSMIC	16.704	Up-regulation
AGC_PKC_PKCa_PRKCA_ST	O14745	SLC9A3R1	P17252	PRKCA	S170	N167I	167	Missense	distal	-3	no	18.463	18.202	EPSD	COSMIC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	O14745	SLC9A3R1	P17252	PRKCA	S280	L285M	285	Missense	distal	5	no	17.370	17.688	EPSD	COSMIC	16.704	Up-regulation
AGC_PKC_PKCa_PRKCA_ST	O14745	SLC9A3R1	P17252	PRKCA	S280	E275V	275	Missense	distal	-5	no	17.370	17.113	EPSD	COSMIC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	O14745	SLC9A3R1	P17252	PRKCA	S280	A277D	277	Missense	distal	-3	no	17.370	16.777	EPSD	COSMIC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	O14745	SLC9A3R1	P17252	PRKCA	S280	E279D	279	Missense	proximal	-1	no	17.370	16.856	EPSD	COSMIC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	O14745	SLC9A3R1	P17252	PRKCA	S308	S302T	302	Missense	distal	-6	no	17.418	17.292	EPSD	COSMIC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	O14745	SLC9A3R1	P17252	PRKCA	S308	T314A	314	Missense	distal	6	no	17.418	17.496	EPSD	COSMIC;GDSC;CCLE	16.704	Up-regulation
AGC_PKC_PKCa_PRKCA_ST	O14745	SLC9A3R1	P17252	PRKCA	S339	A343D	343	Missense	distal	4	no	19.714	19.345	EPSD;PhosphoSitePlus	COSMIC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	O14745	SLC9A3R1	P17252	PRKCA	S340	A343D	343	Missense	distal	3	no	21.773	21.645	PhosphoSitePlus;EPSD	COSMIC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	O14745	SLC9A3R1	P17252	PRKCA	S340	D347E	347	Missense	distal	7	no	21.773	21.720	PhosphoSitePlus;EPSD	COSMIC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	Q96RI1	NR1H4	P17252	PRKCA	S31	P34L	34	Missense	distal	3	no	18.330	17.623	EPSD	COSMIC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	Q96RI1	NR1H4	P17252	PRKCA	S164	G159S	159	Missense	distal	-5	no	21.279	21.143	EPSD	COSMIC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	Q96RI1	NR1H4	P17252	PRKCA	S164	G159C	159	Missense	distal	-5	no	21.279	20.894	EPSD	COSMIC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	Q96RI1	NR1H4	P17252	PRKCA	S164	F160L	160	Missense	distal	-4	no	21.279	20.906	EPSD	COSMIC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	P78536	ADAM17	P17252	PRKCA	T761	R758I	758	Missense	distal	-3	no	17.286	12.799	EPSD	COSMIC	16.704	Loss
AGC_PKC_PKCa_PRKCA_ST	P78536	ADAM17	P17252	PRKCA	T761	H756Q	756	Missense	distal	-5	no	17.286	17.490	EPSD	COSMIC	16.704	Up-regulation
AGC_PKC_PKCa_PRKCA_ST	P78536	ADAM17	P17252	PRKCA	T761	D765N	765	Missense	distal	4	no	17.286	16.929	EPSD	COSMIC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	O95243	MBD4	P17252	PRKCA	S122	L116M	116	Missense	distal	-6	no	17.120	17.182	EPSD	COSMIC	16.704	Up-regulation
AGC_PKC_PKCa_PRKCA_ST	O95243	MBD4	P17252	PRKCA	S253	Q259K	259	Missense	distal	6	no	16.828	16.938	EPSD	COSMIC	16.704	Up-regulation
AGC_PKC_PKCa_PRKCA_ST	O95243	MBD4	P17252	PRKCA	S262	Q259K	259	Missense	distal	-3	no	19.022	19.853	PhosphoSitePlus;EPSD	COSMIC	16.704	Up-regulation
AGC_PKC_PKCa_PRKCA_ST	O95243	MBD4	P17252	PRKCA	S266	Q259K	259	Missense	distal	-7	no	19.954	19.958	EPSD	COSMIC	16.704	Up-regulation
AGC_PKC_PKCa_PRKCA_ST	O95243	MBD4	P17252	PRKCA	T414	K421R	421	Missense	distal	7	no	17.060	17.010	EPSD	COSMIC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	O95243	MBD4	P17252	PRKCA	S415	K421R	421	Missense	distal	6	no	17.854	17.866	EPSD	COSMIC	16.704	Up-regulation
AGC_PKC_PKCa_PRKCA_ST	P48048	KCNJ1	P17252	PRKCA	S44	S44F	44	Missense	central	0	yes	18.873	0.000	EPSD	COSMIC	16.704	Loss
AGC_PKC_PKCa_PRKCA_ST	P48048	KCNJ1	P17252	PRKCA	S44	C49G	49	Missense	distal	5	no	18.873	19.324	EPSD	COSMIC	16.704	Up-regulation
AGC_PKC_PKCa_PRKCA_ST	P48048	KCNJ1	P17252	PRKCA	S44	V43L	43	Missense	proximal	-1	no	18.873	19.916	EPSD	COSMIC	16.704	Up-regulation
AGC_PKC_PKCa_PRKCA_ST	P48048	KCNJ1	P17252	PRKCA	S44	Q38K	38	Missense	distal	-6	no	18.873	19.009	EPSD	COSMIC	16.704	Up-regulation
AGC_PKC_PKCa_PRKCA_ST	P48048	KCNJ1	P17252	PRKCA	T191	R184W	184	Missense	distal	-7	no	18.331	18.314	EPSD	COSMIC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	P48048	KCNJ1	P17252	PRKCA	T191	K187N	187	Missense	distal	-4	no	18.331	17.773	EPSD	COSMIC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	P48048	KCNJ1	P17252	PRKCA	T191	R188L	188	Missense	distal	-3	no	18.331	13.975	EPSD	COSMIC	16.704	Loss
AGC_PKC_PKCa_PRKCA_ST	P48048	KCNJ1	P17252	PRKCA	T191	I192F	192	Missense	proximal	1	no	18.331	18.152	EPSD	COSMIC;GDSC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	P48048	KCNJ1	P17252	PRKCA	T191	T193M	193	Missense	proximal	2	no	18.331	18.694	EPSD	COSMIC	16.704	Up-regulation
AGC_PKC_PKCa_PRKCA_ST	P48048	KCNJ1	P17252	PRKCA	T191	A198T	198	Missense	distal	7	no	18.331	18.340	EPSD	COSMIC	16.704	Up-regulation
AGC_PKC_PKCa_PRKCA_ST	P48048	KCNJ1	P17252	PRKCA	T191	A198S	198	Missense	distal	7	no	18.331	18.333	EPSD	COSMIC	16.704	Up-regulation
AGC_PKC_PKCa_PRKCA_ST	P48048	KCNJ1	P17252	PRKCA	T191	P185L	185	Missense	distal	-6	no	18.331	18.297	EPSD	COSMIC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	P48048	KCNJ1	P17252	PRKCA	S201	R203W	203	Missense	proximal	2	no	18.433	12.993	PhosphoSitePlus;EPSD	COSMIC	16.704	Loss
AGC_PKC_PKCa_PRKCA_ST	P48048	KCNJ1	P17252	PRKCA	S201	K206N	206	Missense	distal	5	no	18.433	17.927	PhosphoSitePlus;EPSD	COSMIC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	P48048	KCNJ1	P17252	PRKCA	S201	G205E	205	Missense	distal	4	no	18.433	18.669	PhosphoSitePlus;EPSD	COSMIC	16.704	Up-regulation
AGC_PKC_PKCa_PRKCA_ST	P48048	KCNJ1	P17252	PRKCA	S201	A198T	198	Missense	distal	-3	no	18.433	18.719	PhosphoSitePlus;EPSD	COSMIC	16.704	Up-regulation
AGC_PKC_PKCa_PRKCA_ST	P48048	KCNJ1	P17252	PRKCA	S201	A198S	198	Missense	distal	-3	no	18.433	20.012	PhosphoSitePlus;EPSD	COSMIC	16.704	Up-regulation
AGC_PKC_PKCa_PRKCA_ST	P55042	RRAD	P17252	PRKCA	S257	D256Y	256	Missense	proximal	-1	no	19.878	19.924	PhosphoSitePlus;EPSD	COSMIC	16.704	Up-regulation
AGC_PKC_PKCa_PRKCA_ST	P55042	RRAD	P17252	PRKCA	S273	A278E	278	Missense	distal	5	no	20.547	20.315	EPSD;PhosphoSitePlus	COSMIC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	P55042	RRAD	P17252	PRKCA	S273	T268I	268	Missense	distal	-5	no	20.547	20.075	EPSD;PhosphoSitePlus	COSMIC;GDSC;CCLE	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	P55042	RRAD	P17252	PRKCA	S290	R284C	284	Missense	distal	-6	no	18.882	18.513	EPSD;PhosphoSitePlus	COSMIC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	P55042	RRAD	P17252	PRKCA	S290	R288P	288	Missense	proximal	-2	no	18.882	15.840	EPSD;PhosphoSitePlus	COSMIC;GDSC	16.704	Loss
AGC_PKC_PKCa_PRKCA_ST	P11831	SRF	P17252	PRKCA	S16	A9T	9	Missense	distal	-7	no	21.197	21.192	EPSD	COSMIC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	P11831	SRF	P17252	PRKCA	S101	E94K	94	Missense	distal	-7	no	17.000	17.008	EPSD	COSMIC	16.704	Up-regulation
AGC_PKC_PKCa_PRKCA_ST	P11831	SRF	P17252	PRKCA	T159	R157C	157	Missense	proximal	-2	no	19.892	18.192	EPSD;PhosphoSitePlus	COSMIC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	P11831	SRF	P17252	PRKCA	T160	R157C	157	Missense	distal	-3	no	18.740	16.000	EPSD	COSMIC	16.704	Loss
AGC_PKC_PKCa_PRKCA_ST	P11831	SRF	P17252	PRKCA	S162	R157C	157	Missense	distal	-5	no	18.939	18.263	PhosphoSitePlus;EPSD	COSMIC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	P11831	SRF	P17252	PRKCA	S237	T244P	244	Missense	distal	7	no	18.458	18.488	EPSD	COSMIC;GDSC;CCLE	16.704	Up-regulation
AGC_PKC_PKCa_PRKCA_ST	P04004	VTN	P17252	PRKCA	S364	P361S	361	Missense	distal	-3	no	18.324	19.302	EPSD	COSMIC	16.704	Up-regulation
AGC_PKC_PKCa_PRKCA_ST	P04004	VTN	P17252	PRKCA	S381	R376C	376	Missense	distal	-5	no	21.671	20.996	EPSD;PhosphoSitePlus	COSMIC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	P04004	VTN	P17252	PRKCA	S381	K377E	377	Missense	distal	-4	no	21.671	20.940	EPSD;PhosphoSitePlus	COSMIC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	P04004	VTN	P17252	PRKCA	S386	R389C	389	Missense	distal	3	no	18.744	16.125	EPSD;PhosphoSitePlus	COSMIC	16.704	Loss
AGC_PKC_PKCa_PRKCA_ST	P04004	VTN	P17252	PRKCA	S393	R394H	394	Missense	proximal	1	no	19.847	19.034	PhosphoSitePlus;EPSD	COSMIC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	P04004	VTN	P17252	PRKCA	S393	T400M	400	Missense	distal	7	no	19.847	19.851	PhosphoSitePlus;EPSD	COSMIC	16.704	Up-regulation
AGC_PKC_PKCa_PRKCA_ST	P04004	VTN	P17252	PRKCA	S393	R395Q	395	Missense	proximal	2	no	19.847	16.013	PhosphoSitePlus;EPSD	COSMIC	16.704	Loss
AGC_PKC_PKCa_PRKCA_ST	P04004	VTN	P17252	PRKCA	S393	R398S	398	Missense	distal	5	no	19.847	19.706	PhosphoSitePlus;EPSD	COSMIC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	P04004	VTN	P17252	PRKCA	S393	R394C	394	Missense	proximal	1	no	19.847	17.011	PhosphoSitePlus;EPSD	COSMIC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	P04004	VTN	P17252	PRKCA	S393	R389C	389	Missense	distal	-4	no	19.847	18.504	PhosphoSitePlus;EPSD	COSMIC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	P04004	VTN	P17252	PRKCA	S397	R394H	394	Missense	distal	-3	no	18.183	14.326	EPSD;PhosphoSitePlus	COSMIC	16.704	Loss
AGC_PKC_PKCa_PRKCA_ST	P04004	VTN	P17252	PRKCA	S397	T400M	400	Missense	distal	3	no	18.183	18.751	EPSD;PhosphoSitePlus	COSMIC	16.704	Up-regulation
AGC_PKC_PKCa_PRKCA_ST	P04004	VTN	P17252	PRKCA	S397	R395Q	395	Missense	proximal	-2	no	18.183	16.424	EPSD;PhosphoSitePlus	COSMIC	16.704	Loss
AGC_PKC_PKCa_PRKCA_ST	P04004	VTN	P17252	PRKCA	S397	R398S	398	Missense	proximal	1	no	18.183	17.009	EPSD;PhosphoSitePlus	COSMIC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	P04004	VTN	P17252	PRKCA	S397	R394C	394	Missense	distal	-3	no	18.183	15.443	EPSD;PhosphoSitePlus	COSMIC	16.704	Loss
AGC_PKC_PKCa_PRKCA_ST	P36542	ATP5F1C	P17252	PRKCA	T32	A26T	26	Missense	distal	-6	no	17.306	17.217	EPSD	COSMIC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	P36542	ATP5F1C	P17252	PRKCA	S47	S47C	47	Missense	central	0	yes	17.179	0.000	EPSD	COSMIC	16.704	Loss
AGC_PKC_PKCa_PRKCA_ST	P36542	ATP5F1C	P17252	PRKCA	S47	A53T	53	Missense	distal	6	no	17.179	17.101	EPSD	COSMIC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	P36542	ATP5F1C	P17252	PRKCA	S47	M48V	48	Missense	proximal	1	no	17.179	17.519	EPSD	COSMIC	16.704	Up-regulation
AGC_PKC_PKCa_PRKCA_ST	P36542	ATP5F1C	P17252	PRKCA	S98	S97F	97	Missense	proximal	-1	no	18.305	17.597	EPSD	COSMIC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	P36542	ATP5F1C	P17252	PRKCA	S98	G95V	95	Missense	distal	-3	no	18.305	17.877	EPSD	COSMIC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	P36542	ATP5F1C	P17252	PRKCA	S98	L93F	93	Missense	distal	-5	no	18.305	18.109	EPSD	COSMIC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	P36542	ATP5F1C	P17252	PRKCA	S98	R100L	100	Missense	proximal	2	no	18.305	13.318	EPSD	COSMIC	16.704	Loss
AGC_PKC_PKCa_PRKCA_ST	P36542	ATP5F1C	P17252	PRKCA	S146	L150M	150	Missense	distal	4	no	16.508	17.351	PhosphoSitePlus	COSMIC	16.704	Gain
AGC_PKC_PKCa_PRKCA_ST	P36542	ATP5F1C	P17252	PRKCA	S241	A235S	235	Missense	distal	-6	no	17.995	18.032	EPSD	COSMIC	16.704	Up-regulation
AGC_PKC_PKCa_PRKCA_ST	P36542	ATP5F1C	P17252	PRKCA	S241	A235T	235	Missense	distal	-6	no	17.995	17.906	EPSD	COSMIC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	P36542	ATP5F1C	P17252	PRKCA	S241	L242P	242	Missense	proximal	1	no	17.995	17.568	EPSD	COSMIC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	P36542	ATP5F1C	P17252	PRKCA	S241	S241F	241	Missense	central	0	yes	17.995	0.000	EPSD	COSMIC	16.704	Loss
AGC_PKC_PKCa_PRKCA_ST	P36542	ATP5F1C	P17252	PRKCA	S241	E244Q	244	Missense	distal	3	no	17.995	16.780	EPSD	COSMIC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	P36542	ATP5F1C	P17252	PRKCA	S241	I238M	238	Missense	distal	-3	no	17.995	19.510	EPSD	COSMIC	16.704	Up-regulation
AGC_PKC_PKCa_PRKCA_ST	P36542	ATP5F1C	P17252	PRKCA	S241	S245Y	245	Missense	distal	4	no	17.995	17.597	EPSD	COSMIC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	P36542	ATP5F1C	P17252	PRKCA	S251	M254I	254	Missense	distal	3	no	18.517	17.236	EPSD	COSMIC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	P36542	ATP5F1C	P17252	PRKCA	S251	E244Q	244	Missense	distal	-7	no	18.517	18.522	EPSD	COSMIC	16.704	Up-regulation
AGC_PKC_PKCa_PRKCA_ST	P36542	ATP5F1C	P17252	PRKCA	S251	T255A	255	Missense	distal	4	no	18.517	18.965	EPSD	COSMIC	16.704	Up-regulation
AGC_PKC_PKCa_PRKCA_ST	P36542	ATP5F1C	P17252	PRKCA	S251	S245Y	245	Missense	distal	-6	no	18.517	18.464	EPSD	COSMIC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	P23528	CFL1	P17252	PRKCA	S23	R21C	21	Missense	proximal	-2	no	19.343	17.643	EPSD;PhosphoSitePlus	COSMIC;GDSC;CCLE	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	P23528	CFL1	P17252	PRKCA	S23	R21H	21	Missense	proximal	-2	no	19.343	14.789	EPSD;PhosphoSitePlus	COSMIC	16.704	Loss
AGC_PKC_PKCa_PRKCA_ST	P23528	CFL1	P17252	PRKCA	S23	V29A	29	Missense	distal	6	no	19.343	19.461	EPSD;PhosphoSitePlus	COSMIC	16.704	Up-regulation
AGC_PKC_PKCa_PRKCA_ST	P23528	CFL1	P17252	PRKCA	S24	R21C	21	Missense	distal	-3	no	21.248	18.509	PhosphoSitePlus;EPSD	COSMIC;GDSC;CCLE	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	P23528	CFL1	P17252	PRKCA	S24	R21H	21	Missense	distal	-3	no	21.248	17.392	PhosphoSitePlus;EPSD	COSMIC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	P23528	CFL1	P17252	PRKCA	S24	V29A	29	Missense	distal	5	no	21.248	21.632	PhosphoSitePlus;EPSD	COSMIC	16.704	Up-regulation
AGC_PKC_PKCa_PRKCA_ST	P23528	CFL1	P17252	PRKCA	S94	E97A	97	Missense	distal	3	no	16.730	16.370	EPSD	COSMIC;GDSC	16.704	Loss
AGC_PKC_PKCa_PRKCA_ST	P23528	CFL1	P17252	PRKCA	S94	K95Q	95	Missense	proximal	1	no	16.730	16.575	EPSD	COSMIC	16.704	Loss
AGC_PKC_PKCa_PRKCA_ST	P23528	CFL1	P17252	PRKCA	S94	Y89N	89	Missense	distal	-5	no	16.730	16.883	EPSD	COSMIC	16.704	Up-regulation
AGC_PKC_PKCa_PRKCA_ST	Q96KS0	EGLN2	P17252	PRKCA	S226	A229V	229	Missense	distal	3	no	19.176	18.920	PhosphoSitePlus;EPSD	COSMIC;GDSC;CCLE	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	Q96KS0	EGLN2	P17252	PRKCA	S226	R233C	233	Missense	distal	7	no	19.176	18.953	PhosphoSitePlus;EPSD	COSMIC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	Q96KS0	EGLN2	P17252	PRKCA	S234	A229V	229	Missense	distal	-5	no	20.437	20.353	EPSD;PhosphoSitePlus	COSMIC;GDSC;CCLE	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	Q96KS0	EGLN2	P17252	PRKCA	S234	R233C	233	Missense	proximal	-1	no	20.437	17.777	EPSD;PhosphoSitePlus	COSMIC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	Q96KS0	EGLN2	P17252	PRKCA	S234	R236H	236	Missense	proximal	2	no	20.437	15.413	EPSD;PhosphoSitePlus	COSMIC;CCLE	16.704	Loss
AGC_PKC_PKCa_PRKCA_ST	Q96KS0	EGLN2	P17252	PRKCA	S252	P248S	248	Missense	distal	-4	no	17.169	17.340	EPSD	COSMIC	16.704	Up-regulation
AGC_PKC_PKCa_PRKCA_ST	Q07869	PPARA	P17252	PRKCA	S179	E180Q	180	Missense	proximal	1	no	19.047	20.497	EPSD;PhosphoSitePlus	COSMIC	16.704	Up-regulation
AGC_PKC_PKCa_PRKCA_ST	Q07869	PPARA	P17252	PRKCA	S230	R226W	226	Missense	distal	-4	no	17.877	17.051	PhosphoSitePlus;EPSD	COSMIC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	P15311	EZR	P17252	PRKCA	T332	V333M	333	Missense	proximal	1	no	18.765	18.426	EPSD	COSMIC;CCLE	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	P15311	EZR	P17252	PRKCA	T332	V333L	333	Missense	proximal	1	no	18.765	18.640	EPSD	COSMIC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	P15311	EZR	P17252	PRKCA	T332	E338G	338	Missense	distal	6	no	18.765	18.722	EPSD	COSMIC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	P04637	TP53	P17252	PRKCA	S9	E11Q	11	Missense	proximal	2	no	15.572	17.438	EPSD	COSMIC;GDSC;CCLE	16.704	Gain
AGC_PKC_PKCa_PRKCA_ST	P04637	TP53	P17252	PRKCA	S15	E17K	17	Missense	proximal	2	no	13.791	19.071	EPSD	COSMIC	16.704	Gain
AGC_PKC_PKCa_PRKCA_ST	P04637	TP53	P17252	PRKCA	S33	L35R	35	Missense	proximal	2	no	13.535	18.522	EPSD	COSMIC	16.704	Gain
AGC_PKC_PKCa_PRKCA_ST	P04637	TP53	P17252	PRKCA	S37	L35R	35	Missense	proximal	-2	no	14.768	17.456	EPSD	COSMIC	16.704	Gain
AGC_PKC_PKCa_PRKCA_ST	P04637	TP53	P17252	PRKCA	S99	S99F	99	Missense	central	0	yes	17.589	0.000	EPSD	COSMIC	16.704	Loss
AGC_PKC_PKCa_PRKCA_ST	P04637	TP53	P17252	PRKCA	S99	S96F	96	Missense	distal	-3	no	17.589	17.839	EPSD	COSMIC	16.704	Up-regulation
AGC_PKC_PKCa_PRKCA_ST	P04637	TP53	P17252	PRKCA	S99	P98S	98	Missense	proximal	-1	no	17.589	17.889	EPSD	COSMIC;CCLE	16.704	Up-regulation
AGC_PKC_PKCa_PRKCA_ST	P04637	TP53	P17252	PRKCA	S99	T102I	102	Missense	distal	3	no	17.589	16.877	EPSD	COSMIC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	P04637	TP53	P17252	PRKCA	S99	S94P	94	Missense	distal	-5	no	17.589	17.915	EPSD	COSMIC	16.704	Up-regulation
AGC_PKC_PKCa_PRKCA_ST	P04637	TP53	P17252	PRKCA	S99	K101R	101	Missense	proximal	2	no	17.589	18.011	EPSD	COSMIC	16.704	Up-regulation
AGC_PKC_PKCa_PRKCA_ST	P04637	TP53	P17252	PRKCA	S99	S94T	94	Missense	distal	-5	no	17.589	17.917	EPSD	COSMIC	16.704	Up-regulation
AGC_PKC_PKCa_PRKCA_ST	P04637	TP53	P17252	PRKCA	S99	P98L	98	Missense	proximal	-1	no	17.589	17.470	EPSD	COSMIC;GDSC;CCLE	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	P04637	TP53	P17252	PRKCA	S99	S95F	95	Missense	distal	-4	no	17.589	17.531	EPSD	COSMIC;CCLE	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	P04637	TP53	P17252	PRKCA	S99	S96C	96	Missense	distal	-3	no	17.589	17.720	EPSD	COSMIC	16.704	Up-regulation
AGC_PKC_PKCa_PRKCA_ST	P04637	TP53	P17252	PRKCA	S99	S106I	106	Missense	distal	7	no	17.589	17.436	EPSD	COSMIC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	P04637	TP53	P17252	PRKCA	S99	P98F	98	Missense	proximal	-1	no	17.589	17.182	EPSD	COSMIC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	P04637	TP53	P17252	PRKCA	S99	T102P	102	Missense	distal	3	no	17.589	17.895	EPSD	COSMIC	16.704	Up-regulation
AGC_PKC_PKCa_PRKCA_ST	P04637	TP53	P17252	PRKCA	S99	S94L	94	Missense	distal	-5	no	17.589	17.888	EPSD	COSMIC	16.704	Up-regulation
AGC_PKC_PKCa_PRKCA_ST	P04637	TP53	P17252	PRKCA	S99	S96P	96	Missense	distal	-3	no	17.589	16.611	EPSD	COSMIC	16.704	Loss
AGC_PKC_PKCa_PRKCA_ST	P04637	TP53	P17252	PRKCA	S99	P98T	98	Missense	proximal	-1	no	17.589	17.511	EPSD	COSMIC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	P04637	TP53	P17252	PRKCA	S99	S96Y	96	Missense	distal	-3	no	17.589	15.899	EPSD	COSMIC	16.704	Loss
AGC_PKC_PKCa_PRKCA_ST	P04637	TP53	P17252	PRKCA	S99	S99P	99	Missense	central	0	yes	17.589	0.000	EPSD	COSMIC	16.704	Loss
AGC_PKC_PKCa_PRKCA_ST	P04637	TP53	P17252	PRKCA	S99	V97I	97	Missense	proximal	-2	no	17.589	16.843	EPSD	COSMIC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	P04637	TP53	P17252	PRKCA	S99	Q104H	104	Missense	distal	5	no	17.589	17.338	EPSD	COSMIC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	P04637	TP53	P17252	PRKCA	S99	L93M	93	Missense	distal	-6	no	17.589	17.652	EPSD	COSMIC	16.704	Up-regulation
AGC_PKC_PKCa_PRKCA_ST	P04637	TP53	P17252	PRKCA	S99	K101N	101	Missense	proximal	2	no	17.589	12.640	EPSD	COSMIC	16.704	Loss
AGC_PKC_PKCa_PRKCA_ST	P04637	TP53	P17252	PRKCA	S99	V97A	97	Missense	proximal	-2	no	17.589	17.346	EPSD	COSMIC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	P04637	TP53	P17252	PRKCA	S99	P92A	92	Missense	distal	-7	no	17.589	17.594	EPSD	COSMIC	16.704	Up-regulation
AGC_PKC_PKCa_PRKCA_ST	P04637	TP53	P17252	PRKCA	S99	Q104L	104	Missense	distal	5	no	17.589	17.266	EPSD	COSMIC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	P04637	TP53	P17252	PRKCA	S99	P92L	92	Missense	distal	-7	no	17.589	17.587	EPSD	COSMIC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	P04637	TP53	P17252	PRKCA	S99	L93P	93	Missense	distal	-6	no	17.589	17.623	EPSD	COSMIC	16.704	Up-regulation
AGC_PKC_PKCa_PRKCA_ST	P04637	TP53	P17252	PRKCA	S99	L93F	93	Missense	distal	-6	no	17.589	17.569	EPSD	COSMIC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	P04637	TP53	P17252	PRKCA	S99	L93H	93	Missense	distal	-6	no	17.589	17.660	EPSD	COSMIC	16.704	Up-regulation
AGC_PKC_PKCa_PRKCA_ST	P04637	TP53	P17252	PRKCA	S99	S95Y	95	Missense	distal	-4	no	17.589	17.396	EPSD	COSMIC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	P04637	TP53	P17252	PRKCA	T211	R209Q	209	Missense	proximal	-2	no	18.834	17.075	EPSD	COSMIC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	P04637	TP53	P17252	PRKCA	T211	R209W	209	Missense	proximal	-2	no	18.834	16.836	EPSD	COSMIC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	P04637	TP53	P17252	PRKCA	T211	R209P	209	Missense	proximal	-2	no	18.834	15.791	EPSD	COSMIC	16.704	Loss
AGC_PKC_PKCa_PRKCA_ST	P04637	TP53	P17252	PRKCA	T211	R209L	209	Missense	proximal	-2	no	18.834	16.146	EPSD	COSMIC	16.704	Loss
AGC_PKC_PKCa_PRKCA_ST	P04637	TP53	P17252	PRKCA	T211	R209G	209	Missense	proximal	-2	no	18.834	15.962	EPSD	COSMIC	16.704	Loss
AGC_PKC_PKCa_PRKCA_ST	P04637	TP53	P17252	PRKCA	T211	R209C	209	Missense	proximal	-2	no	18.834	17.134	EPSD	COSMIC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	P04637	TP53	P17252	PRKCA	T211	E204K	204	Missense	distal	-7	no	18.834	18.842	EPSD	COSMIC	16.704	Up-regulation
AGC_PKC_PKCa_PRKCA_ST	P04637	TP53	P17252	PRKCA	T211	V216A	216	Missense	distal	5	no	18.834	19.218	EPSD	COSMIC	16.704	Up-regulation
AGC_PKC_PKCa_PRKCA_ST	P04637	TP53	P17252	PRKCA	T211	V217A	217	Missense	distal	6	no	18.834	18.952	EPSD	COSMIC	16.704	Up-regulation
AGC_PKC_PKCa_PRKCA_ST	P04637	TP53	P17252	PRKCA	T211	E204G	204	Missense	distal	-7	no	18.834	18.837	EPSD	COSMIC	16.704	Up-regulation
AGC_PKC_PKCa_PRKCA_ST	P04637	TP53	P17252	PRKCA	T211	V218M	218	Missense	distal	7	no	18.834	18.901	EPSD	COSMIC	16.704	Up-regulation
AGC_PKC_PKCa_PRKCA_ST	P04637	TP53	P17252	PRKCA	T211	D208E	208	Missense	distal	-3	no	18.834	18.937	EPSD	COSMIC	16.704	Up-regulation
AGC_PKC_PKCa_PRKCA_ST	P04637	TP53	P17252	PRKCA	T211	F212L	212	Missense	proximal	1	no	18.834	18.176	EPSD	COSMIC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	P04637	TP53	P17252	PRKCA	T211	H214Q	214	Missense	distal	3	no	18.834	17.093	EPSD	COSMIC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	P04637	TP53	P17252	PRKCA	T211	R213W	213	Missense	proximal	2	no	18.834	13.394	EPSD	COSMIC	16.704	Loss
AGC_PKC_PKCa_PRKCA_ST	P04637	TP53	P17252	PRKCA	T211	N210D	210	Missense	proximal	-1	no	18.834	18.496	EPSD	COSMIC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	P04637	TP53	P17252	PRKCA	T211	V218A	218	Missense	distal	7	no	18.834	18.888	EPSD	COSMIC	16.704	Up-regulation
AGC_PKC_PKCa_PRKCA_ST	P04637	TP53	P17252	PRKCA	T211	S215C	215	Missense	distal	4	no	18.834	17.679	EPSD	COSMIC;GDSC;CCLE	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	P04637	TP53	P17252	PRKCA	T211	V218L	218	Missense	distal	7	no	18.834	18.893	EPSD	COSMIC;GDSC;CCLE	16.704	Up-regulation
AGC_PKC_PKCa_PRKCA_ST	P04637	TP53	P17252	PRKCA	T211	E204V	204	Missense	distal	-7	no	18.834	18.833	EPSD	COSMIC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	P04637	TP53	P17252	PRKCA	T211	T211N	211	Missense	central	0	yes	18.834	0.000	EPSD	COSMIC	16.704	Loss
AGC_PKC_PKCa_PRKCA_ST	P04637	TP53	P17252	PRKCA	T211	N210S	210	Missense	proximal	-1	no	18.834	18.991	EPSD	COSMIC	16.704	Up-regulation
AGC_PKC_PKCa_PRKCA_ST	P04637	TP53	P17252	PRKCA	T211	D207G	207	Missense	distal	-4	no	18.834	19.603	EPSD	COSMIC	16.704	Up-regulation
AGC_PKC_PKCa_PRKCA_ST	P04637	TP53	P17252	PRKCA	T211	F212I	212	Missense	proximal	1	no	18.834	19.012	EPSD	COSMIC	16.704	Up-regulation
AGC_PKC_PKCa_PRKCA_ST	P04637	TP53	P17252	PRKCA	T211	D207A	207	Missense	distal	-4	no	18.834	19.599	EPSD	COSMIC	16.704	Up-regulation
AGC_PKC_PKCa_PRKCA_ST	P04637	TP53	P17252	PRKCA	T211	N210H	210	Missense	proximal	-1	no	18.834	19.055	EPSD	COSMIC	16.704	Up-regulation
AGC_PKC_PKCa_PRKCA_ST	P04637	TP53	P17252	PRKCA	T211	V217E	217	Missense	distal	6	no	18.834	18.888	EPSD	COSMIC	16.704	Up-regulation
AGC_PKC_PKCa_PRKCA_ST	P04637	TP53	P17252	PRKCA	T211	R209T	209	Missense	proximal	-2	no	18.834	15.940	EPSD	COSMIC	16.704	Loss
AGC_PKC_PKCa_PRKCA_ST	P04637	TP53	P17252	PRKCA	T211	D207Y	207	Missense	distal	-4	no	18.834	19.319	EPSD	COSMIC	16.704	Up-regulation
AGC_PKC_PKCa_PRKCA_ST	P04637	TP53	P17252	PRKCA	T211	D208Y	208	Missense	distal	-3	no	18.834	19.316	EPSD	COSMIC	16.704	Up-regulation
AGC_PKC_PKCa_PRKCA_ST	P04637	TP53	P17252	PRKCA	T211	V217L	217	Missense	distal	6	no	18.834	18.912	EPSD	COSMIC	16.704	Up-regulation
AGC_PKC_PKCa_PRKCA_ST	P04637	TP53	P17252	PRKCA	T211	L206F	206	Missense	distal	-5	no	18.834	18.638	EPSD	COSMIC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	P04637	TP53	P17252	PRKCA	T211	E204A	204	Missense	distal	-7	no	18.834	18.843	EPSD	COSMIC	16.704	Up-regulation
AGC_PKC_PKCa_PRKCA_ST	P04637	TP53	P17252	PRKCA	T211	D208H	208	Missense	distal	-3	no	18.834	20.019	EPSD	COSMIC	16.704	Up-regulation
AGC_PKC_PKCa_PRKCA_ST	P04637	TP53	P17252	PRKCA	T211	V217M	217	Missense	distal	6	no	18.834	18.922	EPSD	COSMIC	16.704	Up-regulation
AGC_PKC_PKCa_PRKCA_ST	P04637	TP53	P17252	PRKCA	T211	D207E	207	Missense	distal	-4	no	18.834	19.009	EPSD	COSMIC	16.704	Up-regulation
AGC_PKC_PKCa_PRKCA_ST	P04637	TP53	P17252	PRKCA	T211	N210T	210	Missense	proximal	-1	no	18.834	18.613	EPSD	COSMIC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	P04637	TP53	P17252	PRKCA	T211	N210K	210	Missense	proximal	-1	no	18.834	19.436	EPSD	COSMIC	16.704	Up-regulation
AGC_PKC_PKCa_PRKCA_ST	P04637	TP53	P17252	PRKCA	T211	F212S	212	Missense	proximal	1	no	18.834	17.350	EPSD	COSMIC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	P04637	TP53	P17252	PRKCA	T211	H214P	214	Missense	distal	3	no	18.834	18.015	EPSD	COSMIC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	P04637	TP53	P17252	PRKCA	T211	D208I	208	Missense	distal	-3	no	18.834	19.388	EPSD	COSMIC	16.704	Up-regulation
AGC_PKC_PKCa_PRKCA_ST	P04637	TP53	P17252	PRKCA	T211	F212Y	212	Missense	proximal	1	no	18.834	18.161	EPSD	COSMIC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	P04637	TP53	P17252	PRKCA	T211	H214A	214	Missense	distal	3	no	18.834	17.948	EPSD	COSMIC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	P04637	TP53	P17252	PRKCA	S215	V217A	217	Missense	proximal	2	no	16.529	16.845	EPSD	COSMIC	16.704	Gain
AGC_PKC_PKCa_PRKCA_ST	P04637	TP53	P17252	PRKCA	S215	V218M	218	Missense	distal	3	no	16.529	17.115	EPSD	COSMIC	16.704	Gain
AGC_PKC_PKCa_PRKCA_ST	P04637	TP53	P17252	PRKCA	S215	V218A	218	Missense	distal	3	no	16.529	16.785	EPSD	COSMIC	16.704	Gain
AGC_PKC_PKCa_PRKCA_ST	P04637	TP53	P17252	PRKCA	S215	T211N	211	Missense	distal	-4	no	16.529	16.861	EPSD	COSMIC	16.704	Gain
AGC_PKC_PKCa_PRKCA_ST	P04637	TP53	P17252	PRKCA	S215	P219R	219	Missense	distal	4	no	16.529	16.975	EPSD	COSMIC	16.704	Gain
AGC_PKC_PKCa_PRKCA_ST	P04637	TP53	P17252	PRKCA	S215	P219S	219	Missense	distal	4	no	16.529	16.729	EPSD	COSMIC	16.704	Gain
AGC_PKC_PKCa_PRKCA_ST	P04637	TP53	P17252	PRKCA	S215	T211S	211	Missense	distal	-4	no	16.529	17.191	EPSD	COSMIC	16.704	Gain
AGC_PKC_PKCa_PRKCA_ST	P04637	TP53	P17252	PRKCA	S215	V217M	217	Missense	proximal	2	no	16.529	17.095	EPSD	COSMIC	16.704	Gain
AGC_PKC_PKCa_PRKCA_ST	P04637	TP53	P17252	PRKCA	S215	N210T	210	Missense	distal	-5	no	16.529	16.786	EPSD	COSMIC	16.704	Gain
AGC_PKC_PKCa_PRKCA_ST	P04637	TP53	P17252	PRKCA	S215	N210K	210	Missense	distal	-5	no	16.529	16.872	EPSD	COSMIC	16.704	Gain
AGC_PKC_PKCa_PRKCA_ST	P04637	TP53	P17252	PRKCA	S269	A276S	276	Missense	distal	7	no	17.682	17.684	EPSD	COSMIC	16.704	Up-regulation
AGC_PKC_PKCa_PRKCA_ST	P04637	TP53	P17252	PRKCA	S269	G262H	262	Missense	distal	-7	no	17.682	17.684	EPSD	COSMIC	16.704	Up-regulation
AGC_PKC_PKCa_PRKCA_ST	P04637	TP53	P17252	PRKCA	S269	N263H	263	Missense	distal	-6	no	17.682	17.745	EPSD	COSMIC	16.704	Up-regulation
AGC_PKC_PKCa_PRKCA_ST	P04637	TP53	P17252	PRKCA	S269	G266A	266	Missense	distal	-3	no	17.682	16.495	EPSD	COSMIC	16.704	Loss
AGC_PKC_PKCa_PRKCA_ST	P04637	TP53	P17252	PRKCA	S269	S269N	269	Missense	central	0	yes	17.682	0.000	EPSD	COSMIC	16.704	Loss
AGC_PKC_PKCa_PRKCA_ST	P04637	TP53	P17252	PRKCA	S269	V274I	274	Missense	distal	5	no	17.682	17.769	EPSD	COSMIC	16.704	Up-regulation
AGC_PKC_PKCa_PRKCA_ST	P04637	TP53	P17252	PRKCA	S269	L265M	265	Missense	distal	-4	no	17.682	18.385	EPSD	COSMIC	16.704	Up-regulation
AGC_PKC_PKCa_PRKCA_ST	P04637	TP53	P17252	PRKCA	S269	F270Y	270	Missense	proximal	1	no	17.682	17.009	EPSD	COSMIC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	P04637	TP53	P17252	PRKCA	S269	L264V	264	Missense	distal	-5	no	17.682	17.246	EPSD	COSMIC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	P04637	TP53	P17252	PRKCA	S269	S269G	269	Missense	central	0	yes	17.682	0.000	EPSD	COSMIC	16.704	Loss
AGC_PKC_PKCa_PRKCA_ST	P04637	TP53	P17252	PRKCA	S269	R273Q	273	Missense	distal	4	no	17.682	17.464	EPSD	COSMIC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	P04637	TP53	P17252	PRKCA	S269	N268H	268	Missense	proximal	-1	no	17.682	17.904	EPSD	COSMIC	16.704	Up-regulation
AGC_PKC_PKCa_PRKCA_ST	P04637	TP53	P17252	PRKCA	S269	N263I	263	Missense	distal	-6	no	17.682	17.642	EPSD	COSMIC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	P04637	TP53	P17252	PRKCA	S269	L264P	264	Missense	distal	-5	no	17.682	17.708	EPSD	COSMIC	16.704	Up-regulation
AGC_PKC_PKCa_PRKCA_ST	P04637	TP53	P17252	PRKCA	S269	E271P	271	Missense	proximal	2	no	17.682	18.180	EPSD	COSMIC	16.704	Up-regulation
AGC_PKC_PKCa_PRKCA_ST	P04637	TP53	P17252	PRKCA	S269	L264R	264	Missense	distal	-5	no	17.682	17.809	EPSD	COSMIC;GDSC;CCLE	16.704	Up-regulation
AGC_PKC_PKCa_PRKCA_ST	P04637	TP53	P17252	PRKCA	S269	R273Y	273	Missense	distal	4	no	17.682	17.038	EPSD	COSMIC;CCLE	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	P04637	TP53	P17252	PRKCA	S269	N263D	263	Missense	distal	-6	no	17.682	17.655	EPSD	COSMIC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	P04637	TP53	P17252	PRKCA	S269	A276T	276	Missense	distal	7	no	17.682	17.690	EPSD	COSMIC	16.704	Up-regulation
AGC_PKC_PKCa_PRKCA_ST	P04637	TP53	P17252	PRKCA	S269	S269C	269	Missense	central	0	yes	17.682	0.000	EPSD	COSMIC	16.704	Loss
AGC_PKC_PKCa_PRKCA_ST	P04637	TP53	P17252	PRKCA	S269	L264I	264	Missense	distal	-5	no	17.682	17.238	EPSD	COSMIC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	P04637	TP53	P17252	PRKCA	S269	N268K	268	Missense	proximal	-1	no	17.682	18.284	EPSD	COSMIC	16.704	Up-regulation
AGC_PKC_PKCa_PRKCA_ST	P04637	TP53	P17252	PRKCA	S269	A276F	276	Missense	distal	7	no	17.682	17.620	EPSD	COSMIC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	P04637	TP53	P17252	PRKCA	S269	G266T	266	Missense	distal	-3	no	17.682	16.780	EPSD	COSMIC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	P04637	TP53	P17252	PRKCA	S269	G266K	266	Missense	distal	-3	no	17.682	18.917	EPSD	COSMIC	16.704	Up-regulation
AGC_PKC_PKCa_PRKCA_ST	P04637	TP53	P17252	PRKCA	S269	E271G	271	Missense	proximal	2	no	17.682	18.137	EPSD	COSMIC	16.704	Up-regulation
AGC_PKC_PKCa_PRKCA_ST	P04637	TP53	P17252	PRKCA	S269	L264Q	264	Missense	distal	-5	no	17.682	17.657	EPSD	COSMIC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	P04637	TP53	P17252	PRKCA	S269	S269I	269	Missense	central	0	yes	17.682	0.000	EPSD	COSMIC	16.704	Loss
AGC_PKC_PKCa_PRKCA_ST	P04637	TP53	P17252	PRKCA	S269	S269R	269	Missense	central	0	yes	17.682	0.000	EPSD	COSMIC	16.704	Loss
AGC_PKC_PKCa_PRKCA_ST	P04637	TP53	P17252	PRKCA	S269	G262R	262	Missense	distal	-7	no	17.682	17.691	EPSD	COSMIC	16.704	Up-regulation
AGC_PKC_PKCa_PRKCA_ST	P04637	TP53	P17252	PRKCA	S269	N263K	263	Missense	distal	-6	no	17.682	17.805	EPSD	COSMIC	16.704	Up-regulation
AGC_PKC_PKCa_PRKCA_ST	P04637	TP53	P17252	PRKCA	S269	V272K	272	Missense	distal	3	no	17.682	18.913	EPSD	COSMIC	16.704	Up-regulation
AGC_PKC_PKCa_PRKCA_ST	P04637	TP53	P17252	PRKCA	S269	N268F	268	Missense	proximal	-1	no	17.682	17.132	EPSD	COSMIC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	P04637	TP53	P17252	PRKCA	S269	L265Q	265	Missense	distal	-4	no	17.682	17.929	EPSD	COSMIC	16.704	Up-regulation
AGC_PKC_PKCa_PRKCA_ST	P04637	TP53	P17252	PRKCA	S269	N268S	268	Missense	proximal	-1	no	17.682	17.839	EPSD	COSMIC	16.704	Up-regulation
AGC_PKC_PKCa_PRKCA_ST	P04637	TP53	P17252	PRKCA	S269	G262S	262	Missense	distal	-7	no	17.682	17.686	EPSD	COSMIC;GDSC	16.704	Up-regulation
AGC_PKC_PKCa_PRKCA_ST	P04637	TP53	P17252	PRKCA	S269	G266S	266	Missense	distal	-3	no	17.682	18.074	EPSD	COSMIC	16.704	Up-regulation
AGC_PKC_PKCa_PRKCA_ST	P04637	TP53	P17252	PRKCA	T284	D281R	281	Missense	distal	-3	no	12.156	17.198	EPSD	COSMIC	16.704	Gain
AGC_PKC_PKCa_PRKCA_ST	P04637	TP53	P17252	PRKCA	T304	S303C	303	Missense	proximal	-1	no	16.706	14.433	EPSD	COSMIC	16.704	Loss
AGC_PKC_PKCa_PRKCA_ST	P04637	TP53	P17252	PRKCA	T304	S303F	303	Missense	proximal	-1	no	16.706	15.998	EPSD	COSMIC	16.704	Loss
AGC_PKC_PKCa_PRKCA_ST	P04637	TP53	P17252	PRKCA	T304	P301L	301	Missense	distal	-3	no	16.706	16.199	EPSD	COSMIC	16.704	Loss
AGC_PKC_PKCa_PRKCA_ST	P04637	TP53	P17252	PRKCA	T304	K305T	305	Missense	proximal	1	no	16.706	15.822	EPSD	COSMIC	16.704	Loss
AGC_PKC_PKCa_PRKCA_ST	P04637	TP53	P17252	PRKCA	T304	P300L	300	Missense	distal	-4	no	16.706	16.446	EPSD	COSMIC	16.704	Loss
AGC_PKC_PKCa_PRKCA_ST	P04637	TP53	P17252	PRKCA	T304	N310T	310	Missense	distal	6	no	16.706	16.760	EPSD	COSMIC	16.704	Up-regulation
AGC_PKC_PKCa_PRKCA_ST	P04637	TP53	P17252	PRKCA	T304	T304N	304	Missense	central	0	yes	16.706	0.000	EPSD	COSMIC	16.704	Loss
AGC_PKC_PKCa_PRKCA_ST	P04637	TP53	P17252	PRKCA	T304	H297P	297	Missense	distal	-7	no	16.706	16.705	EPSD	COSMIC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	P04637	TP53	P17252	PRKCA	T304	P309S	309	Missense	distal	5	no	16.706	16.547	EPSD	COSMIC;GDSC;CCLE	16.704	Loss
AGC_PKC_PKCa_PRKCA_ST	P04637	TP53	P17252	PRKCA	T304	G302E	302	Missense	proximal	-2	no	16.706	15.452	EPSD	COSMIC	16.704	Loss
AGC_PKC_PKCa_PRKCA_ST	P04637	TP53	P17252	PRKCA	T304	N310L	310	Missense	distal	6	no	16.706	16.798	EPSD	COSMIC	16.704	Up-regulation
AGC_PKC_PKCa_PRKCA_ST	P04637	TP53	P17252	PRKCA	T304	K305N	305	Missense	proximal	1	no	16.706	15.542	EPSD	COSMIC	16.704	Loss
AGC_PKC_PKCa_PRKCA_ST	P04637	TP53	P17252	PRKCA	T304	H297Y	297	Missense	distal	-7	no	16.706	16.708	EPSD	COSMIC	16.704	Up-regulation
AGC_PKC_PKCa_PRKCA_ST	P04637	TP53	P17252	PRKCA	T304	P300S	300	Missense	distal	-4	no	16.706	16.877	EPSD	COSMIC	16.704	Up-regulation
AGC_PKC_PKCa_PRKCA_ST	P04637	TP53	P17252	PRKCA	T304	S303N	303	Missense	proximal	-1	no	16.706	16.548	EPSD	COSMIC	16.704	Loss
AGC_PKC_PKCa_PRKCA_ST	P04637	TP53	P17252	PRKCA	T304	N311Y	311	Missense	distal	7	no	16.706	16.724	EPSD	COSMIC	16.704	Up-regulation
AGC_PKC_PKCa_PRKCA_ST	P04637	TP53	P17252	PRKCA	T304	T304A	304	Missense	central	0	yes	16.706	0.000	EPSD	COSMIC	16.704	Loss
AGC_PKC_PKCa_PRKCA_ST	P04637	TP53	P17252	PRKCA	T304	L299P	299	Missense	distal	-5	no	16.706	16.732	EPSD	COSMIC	16.704	Up-regulation
AGC_PKC_PKCa_PRKCA_ST	P04637	TP53	P17252	PRKCA	T304	R306P	306	Missense	proximal	2	no	16.706	11.503	EPSD	COSMIC	16.704	Loss
AGC_PKC_PKCa_PRKCA_ST	P04637	TP53	P17252	PRKCA	T304	A307T	307	Missense	distal	3	no	16.706	16.467	EPSD	COSMIC	16.704	Loss
AGC_PKC_PKCa_PRKCA_ST	P04637	TP53	P17252	PRKCA	T304	N311K	311	Missense	distal	7	no	16.706	16.826	EPSD	COSMIC	16.704	Up-regulation
AGC_PKC_PKCa_PRKCA_ST	P04637	TP53	P17252	PRKCA	T304	P300R	300	Missense	distal	-4	no	16.706	17.071	EPSD	COSMIC	16.704	Up-regulation
AGC_PKC_PKCa_PRKCA_ST	P04637	TP53	P17252	PRKCA	T304	K305E	305	Missense	proximal	1	no	16.706	15.102	EPSD	COSMIC	16.704	Loss
AGC_PKC_PKCa_PRKCA_ST	P04637	TP53	P17252	PRKCA	T304	P301S	301	Missense	distal	-3	no	16.706	17.685	EPSD	COSMIC	16.704	Up-regulation
AGC_PKC_PKCa_PRKCA_ST	P04637	TP53	P17252	PRKCA	T304	N310H	310	Missense	distal	6	no	16.706	16.803	EPSD	COSMIC	16.704	Up-regulation
AGC_PKC_PKCa_PRKCA_ST	P04637	TP53	P17252	PRKCA	T304	P300A	300	Missense	distal	-4	no	16.706	16.964	EPSD	COSMIC	16.704	Up-regulation
AGC_PKC_PKCa_PRKCA_ST	P04637	TP53	P17252	PRKCA	T304	R306Q	306	Missense	proximal	2	no	16.706	12.872	EPSD	COSMIC	16.704	Loss
AGC_PKC_PKCa_PRKCA_ST	P04637	TP53	P17252	PRKCA	T304	K305R	305	Missense	proximal	1	no	16.706	16.669	EPSD	COSMIC	16.704	Loss
AGC_PKC_PKCa_PRKCA_ST	P04637	TP53	P17252	PRKCA	T304	E298V	298	Missense	distal	-6	no	16.706	16.594	EPSD	COSMIC	16.704	Loss
AGC_PKC_PKCa_PRKCA_ST	P04637	TP53	P17252	PRKCA	T304	L299V	299	Missense	distal	-5	no	16.706	16.270	EPSD	COSMIC	16.704	Loss
AGC_PKC_PKCa_PRKCA_ST	P04637	TP53	P17252	PRKCA	T304	S303T	303	Missense	proximal	-1	no	16.706	16.328	EPSD	COSMIC	16.704	Loss
AGC_PKC_PKCa_PRKCA_ST	P04637	TP53	P17252	PRKCA	T304	L308M	308	Missense	distal	4	no	16.706	17.549	EPSD	COSMIC	16.704	Up-regulation
AGC_PKC_PKCa_PRKCA_ST	P04637	TP53	P17252	PRKCA	T304	N311H	311	Missense	distal	7	no	16.706	16.705	EPSD	COSMIC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	P04637	TP53	P17252	PRKCA	T304	L308V	308	Missense	distal	4	no	16.706	16.177	EPSD	COSMIC	16.704	Loss
AGC_PKC_PKCa_PRKCA_ST	P04637	TP53	P17252	PRKCA	T304	E298Q	298	Missense	distal	-6	no	16.706	16.637	EPSD	COSMIC	16.704	Loss
AGC_PKC_PKCa_PRKCA_ST	P04637	TP53	P17252	PRKCA	T304	E298D	298	Missense	distal	-6	no	16.706	16.623	EPSD	COSMIC	16.704	Loss
AGC_PKC_PKCa_PRKCA_ST	P04637	TP53	P17252	PRKCA	T304	T304I	304	Missense	central	0	yes	16.706	0.000	EPSD	COSMIC	16.704	Loss
AGC_PKC_PKCa_PRKCA_ST	P04637	TP53	P17252	PRKCA	T304	E298K	298	Missense	distal	-6	no	16.706	16.773	EPSD	COSMIC	16.704	Up-regulation
AGC_PKC_PKCa_PRKCA_ST	P04637	TP53	P17252	PRKCA	T304	N310D	310	Missense	distal	6	no	16.706	16.790	EPSD	COSMIC	16.704	Up-regulation
AGC_PKC_PKCa_PRKCA_ST	P04637	TP53	P17252	PRKCA	T304	N311D	311	Missense	distal	7	no	16.706	16.733	EPSD	COSMIC	16.704	Up-regulation
AGC_PKC_PKCa_PRKCA_ST	P04637	TP53	P17252	PRKCA	T304	P301A	301	Missense	distal	-3	no	16.706	16.106	EPSD	COSMIC	16.704	Loss
AGC_PKC_PKCa_PRKCA_ST	P04637	TP53	P17252	PRKCA	T304	P301Q	301	Missense	distal	-3	no	16.706	17.697	EPSD	COSMIC	16.704	Up-regulation
AGC_PKC_PKCa_PRKCA_ST	P04637	TP53	P17252	PRKCA	T304	P309R	309	Missense	distal	5	no	16.706	16.688	EPSD	COSMIC	16.704	Loss
AGC_PKC_PKCa_PRKCA_ST	P04637	TP53	P17252	PRKCA	T304	H297N	297	Missense	distal	-7	no	16.706	16.703	EPSD	COSMIC	16.704	Loss
AGC_PKC_PKCa_PRKCA_ST	P04637	TP53	P17252	PRKCA	T304	G302R	302	Missense	proximal	-2	no	16.706	19.578	EPSD	COSMIC	16.704	Up-regulation
AGC_PKC_PKCa_PRKCA_ST	P04637	TP53	P17252	PRKCA	T304	E298A	298	Missense	distal	-6	no	16.706	16.670	EPSD	COSMIC	16.704	Loss
AGC_PKC_PKCa_PRKCA_ST	P04637	TP53	P17252	PRKCA	T304	A307S	307	Missense	distal	3	no	16.706	16.913	EPSD	COSMIC	16.704	Up-regulation
AGC_PKC_PKCa_PRKCA_ST	P04637	TP53	P17252	PRKCA	T304	E298G	298	Missense	distal	-6	no	16.706	16.673	EPSD	COSMIC	16.704	Loss
AGC_PKC_PKCa_PRKCA_ST	P04637	TP53	P17252	PRKCA	S315	Q317R	317	Missense	proximal	2	no	14.260	18.094	EPSD	COSMIC	16.704	Gain
AGC_PKC_PKCa_PRKCA_ST	P04637	TP53	P17252	PRKCA	S315	Q317K	317	Missense	proximal	2	no	14.260	17.672	EPSD	COSMIC	16.704	Gain
AGC_PKC_PKCa_PRKCA_ST	P04637	TP53	P17252	PRKCA	S371	S367F	367	Missense	distal	-4	no	18.173	18.115	EPSD;PhosphoSitePlus	COSMIC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	P04637	TP53	P17252	PRKCA	S371	K370N	370	Missense	proximal	-1	no	18.173	17.571	EPSD;PhosphoSitePlus	COSMIC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	P04637	TP53	P17252	PRKCA	S371	A364D	364	Missense	distal	-7	no	18.173	18.167	EPSD;PhosphoSitePlus	COSMIC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	P04637	TP53	P17252	PRKCA	S371	H365Y	365	Missense	distal	-6	no	18.173	18.114	EPSD;PhosphoSitePlus	COSMIC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	P04637	TP53	P17252	PRKCA	S371	A364T	364	Missense	distal	-7	no	18.173	18.168	EPSD;PhosphoSitePlus	COSMIC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	P04637	TP53	P17252	PRKCA	S371	S376T	376	Missense	distal	5	no	18.173	17.997	EPSD;PhosphoSitePlus	COSMIC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	P04637	TP53	P17252	PRKCA	S371	S366A	366	Missense	distal	-5	no	18.173	18.120	EPSD;PhosphoSitePlus	COSMIC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	P04637	TP53	P17252	PRKCA	S371	T377I	377	Missense	distal	6	no	18.173	18.187	EPSD;PhosphoSitePlus	COSMIC	16.704	Up-regulation
AGC_PKC_PKCa_PRKCA_ST	P04637	TP53	P17252	PRKCA	S371	S378F	378	Missense	distal	7	no	18.173	18.109	EPSD;PhosphoSitePlus	COSMIC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	P04637	TP53	P17252	PRKCA	S371	K370Q	370	Missense	proximal	-1	no	18.173	17.298	EPSD;PhosphoSitePlus	COSMIC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	P04637	TP53	P17252	PRKCA	S371	K373R	373	Missense	proximal	2	no	18.173	18.594	EPSD;PhosphoSitePlus	COSMIC	16.704	Up-regulation
AGC_PKC_PKCa_PRKCA_ST	P04637	TP53	P17252	PRKCA	S371	S376F	376	Missense	distal	5	no	18.173	18.207	EPSD;PhosphoSitePlus	COSMIC	16.704	Up-regulation
AGC_PKC_PKCa_PRKCA_ST	P04637	TP53	P17252	PRKCA	S371	G374S	374	Missense	distal	3	no	18.173	17.421	EPSD;PhosphoSitePlus	COSMIC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	P04637	TP53	P17252	PRKCA	S371	S376A	376	Missense	distal	5	no	18.173	18.276	EPSD;PhosphoSitePlus	COSMIC	16.704	Up-regulation
AGC_PKC_PKCa_PRKCA_ST	P04637	TP53	P17252	PRKCA	S371	S371P	371	Missense	central	0	yes	18.173	0.000	EPSD;PhosphoSitePlus	COSMIC	16.704	Loss
AGC_PKC_PKCa_PRKCA_ST	P04637	TP53	P17252	PRKCA	S376	K373R	373	Missense	distal	-3	no	15.143	17.169	EPSD;PhosphoSitePlus	COSMIC	16.704	Gain
AGC_PKC_PKCa_PRKCA_ST	P04637	TP53	P17252	PRKCA	T377	K370N	370	Missense	distal	-7	no	17.083	17.078	PhosphoSitePlus;EPSD	COSMIC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	P04637	TP53	P17252	PRKCA	T377	L383F	383	Missense	distal	6	no	17.083	17.052	PhosphoSitePlus;EPSD	COSMIC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	P04637	TP53	P17252	PRKCA	T377	R379H	379	Missense	proximal	2	no	17.083	12.059	PhosphoSitePlus;EPSD	COSMIC	16.704	Loss
AGC_PKC_PKCa_PRKCA_ST	P04637	TP53	P17252	PRKCA	T377	S376T	376	Missense	proximal	-1	no	17.083	16.705	PhosphoSitePlus;EPSD	COSMIC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	P04637	TP53	P17252	PRKCA	T377	H380Y	380	Missense	distal	3	no	17.083	15.527	PhosphoSitePlus;EPSD	COSMIC	16.704	Loss
AGC_PKC_PKCa_PRKCA_ST	P04637	TP53	P17252	PRKCA	T377	T377I	377	Missense	central	0	yes	17.083	0.000	PhosphoSitePlus;EPSD	COSMIC	16.704	Loss
AGC_PKC_PKCa_PRKCA_ST	P04637	TP53	P17252	PRKCA	T377	S378F	378	Missense	proximal	1	no	17.083	18.567	PhosphoSitePlus;EPSD	COSMIC	16.704	Up-regulation
AGC_PKC_PKCa_PRKCA_ST	P04637	TP53	P17252	PRKCA	T377	K370Q	370	Missense	distal	-7	no	17.083	17.080	PhosphoSitePlus;EPSD	COSMIC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	P04637	TP53	P17252	PRKCA	T377	K381N	381	Missense	distal	4	no	17.083	15.956	PhosphoSitePlus;EPSD	COSMIC	16.704	Loss
AGC_PKC_PKCa_PRKCA_ST	P04637	TP53	P17252	PRKCA	T377	R379P	379	Missense	proximal	2	no	17.083	11.880	PhosphoSitePlus;EPSD	COSMIC	16.704	Loss
AGC_PKC_PKCa_PRKCA_ST	P04637	TP53	P17252	PRKCA	T377	M384I	384	Missense	distal	7	no	17.083	16.919	PhosphoSitePlus;EPSD	COSMIC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	P04637	TP53	P17252	PRKCA	T377	K373R	373	Missense	distal	-4	no	17.083	17.048	PhosphoSitePlus;EPSD	COSMIC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	P04637	TP53	P17252	PRKCA	T377	S376F	376	Missense	proximal	-1	no	17.083	16.375	PhosphoSitePlus;EPSD	COSMIC	16.704	Loss
AGC_PKC_PKCa_PRKCA_ST	P04637	TP53	P17252	PRKCA	T377	G374S	374	Missense	distal	-3	no	17.083	17.475	PhosphoSitePlus;EPSD	COSMIC	16.704	Up-regulation
AGC_PKC_PKCa_PRKCA_ST	P04637	TP53	P17252	PRKCA	T377	S376A	376	Missense	proximal	-1	no	17.083	16.524	PhosphoSitePlus;EPSD	COSMIC	16.704	Loss
AGC_PKC_PKCa_PRKCA_ST	P04637	TP53	P17252	PRKCA	T377	S371P	371	Missense	distal	-6	no	17.083	17.051	PhosphoSitePlus;EPSD	COSMIC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	P38936	CDKN1A	P17252	PRKCA	S153	R156W	156	Missense	distal	3	no	18.429	15.496	EPSD;PhosphoSitePlus	COSMIC;GDSC;CCLE	16.704	Loss
AGC_PKC_PKCa_PRKCA_ST	P38936	CDKN1A	P17252	PRKCA	S153	I158M	158	Missense	distal	5	no	18.429	18.750	EPSD;PhosphoSitePlus	COSMIC	16.704	Up-regulation
AGC_PKC_PKCa_PRKCA_ST	P38936	CDKN1A	P17252	PRKCA	S153	D149N	149	Missense	distal	-4	no	18.429	18.778	EPSD;PhosphoSitePlus	COSMIC	16.704	Up-regulation
AGC_PKC_PKCa_PRKCA_ST	P38936	CDKN1A	P17252	PRKCA	S153	R155C	155	Missense	proximal	2	no	18.429	14.079	EPSD;PhosphoSitePlus	COSMIC	16.704	Loss
AGC_PKC_PKCa_PRKCA_ST	P38936	CDKN1A	P17252	PRKCA	S160	I158M	158	Missense	proximal	-2	no	15.826	17.432	EPSD	COSMIC	16.704	Gain
AGC_PKC_PKCa_PRKCA_ST	P60983	GMFB	P17252	PRKCA	T27	A31V	31	Missense	distal	4	no	16.999	15.661	EPSD	COSMIC;GDSC;CCLE	16.704	Loss
AGC_PKC_PKCa_PRKCA_ST	P60983	GMFB	P17252	PRKCA	T27	R24C	24	Missense	distal	-3	no	16.999	14.260	EPSD	COSMIC	16.704	Loss
AGC_PKC_PKCa_PRKCA_ST	P60880	SNAP25	P17252	PRKCA	S28	R30C	30	Missense	proximal	2	no	21.165	16.815	EPSD	COSMIC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	P60880	SNAP25	P17252	PRKCA	S28	R30H	30	Missense	proximal	2	no	21.165	16.142	EPSD	COSMIC	16.704	Loss
AGC_PKC_PKCa_PRKCA_ST	P60880	SNAP25	P17252	PRKCA	T138	E145K	145	Missense	distal	7	no	16.985	17.131	EPSD;PhosphoSitePlus	COSMIC	16.704	Up-regulation
AGC_PKC_PKCa_PRKCA_ST	P60880	SNAP25	P17252	PRKCA	T138	R142Q	142	Missense	distal	4	no	16.985	16.767	EPSD;PhosphoSitePlus	COSMIC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	P60880	SNAP25	P17252	PRKCA	T138	G131C	131	Missense	distal	-7	no	16.985	16.975	EPSD;PhosphoSitePlus	COSMIC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	Q8NF50	DOCK8	P17252	PRKCA	S6	A13T	13	Missense	distal	7	no	17.409	17.418	EPSD	COSMIC	16.704	Up-regulation
AGC_PKC_PKCa_PRKCA_ST	Q8NF50	DOCK8	P17252	PRKCA	S446	L439V	439	Missense	distal	-7	no	22.582	22.579	EPSD	COSMIC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	Q8NF50	DOCK8	P17252	PRKCA	S446	A440S	440	Missense	distal	-6	no	22.582	22.619	EPSD	COSMIC	16.704	Up-regulation
AGC_PKC_PKCa_PRKCA_ST	Q8NF50	DOCK8	P17252	PRKCA	S451	E454G	454	Missense	distal	3	no	16.332	16.931	EPSD	COSMIC	16.704	Gain
AGC_PKC_PKCa_PRKCA_ST	Q8NF50	DOCK8	P17252	PRKCA	S495	Y491C	491	Missense	distal	-4	no	17.500	16.544	EPSD	COSMIC	16.704	Loss
AGC_PKC_PKCa_PRKCA_ST	Q8NF50	DOCK8	P17252	PRKCA	S902	M901V	901	Missense	proximal	-1	no	17.839	15.717	EPSD	COSMIC	16.704	Loss
AGC_PKC_PKCa_PRKCA_ST	Q8NF50	DOCK8	P17252	PRKCA	S902	S902G	902	Missense	central	0	yes	17.839	0.000	EPSD	COSMIC	16.704	Loss
AGC_PKC_PKCa_PRKCA_ST	Q8NF50	DOCK8	P17252	PRKCA	S933	C932F	932	Missense	proximal	-1	no	15.148	16.713	EPSD	COSMIC	16.704	Gain
AGC_PKC_PKCa_PRKCA_ST	Q8NF50	DOCK8	P17252	PRKCA	S936	G941D	941	Missense	distal	5	no	17.978	17.898	EPSD	COSMIC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	Q8NF50	DOCK8	P17252	PRKCA	S936	C939F	939	Missense	distal	3	no	17.978	18.693	EPSD	COSMIC	16.704	Up-regulation
AGC_PKC_PKCa_PRKCA_ST	Q8NF50	DOCK8	P17252	PRKCA	S936	R930H	930	Missense	distal	-6	no	17.978	17.911	EPSD	COSMIC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	Q8NF50	DOCK8	P17252	PRKCA	S936	C932F	932	Missense	distal	-4	no	17.978	19.071	EPSD	COSMIC	16.704	Up-regulation
AGC_PKC_PKCa_PRKCA_ST	Q8NF50	DOCK8	P17252	PRKCA	S956	K958N	958	Missense	proximal	2	no	21.610	16.661	EPSD	COSMIC	16.704	Loss
AGC_PKC_PKCa_PRKCA_ST	Q8NF50	DOCK8	P17252	PRKCA	S956	R953C	953	Missense	distal	-3	no	21.610	18.871	EPSD	COSMIC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	Q8NF50	DOCK8	P17252	PRKCA	S956	S956G	956	Missense	central	0	yes	21.610	0.000	EPSD	COSMIC	16.704	Loss
AGC_PKC_PKCa_PRKCA_ST	Q8NF50	DOCK8	P17252	PRKCA	S956	E962K	962	Missense	distal	6	no	21.610	21.705	EPSD	COSMIC	16.704	Up-regulation
AGC_PKC_PKCa_PRKCA_ST	Q8NF50	DOCK8	P17252	PRKCA	S956	P952S	952	Missense	distal	-4	no	21.610	21.782	EPSD	COSMIC	16.704	Up-regulation
AGC_PKC_PKCa_PRKCA_ST	Q8NF50	DOCK8	P17252	PRKCA	S1080	Q1078K	1078	Missense	proximal	-2	no	17.979	18.110	EPSD	COSMIC	16.704	Up-regulation
AGC_PKC_PKCa_PRKCA_ST	Q8NF50	DOCK8	P17252	PRKCA	S1080	L1086I	1086	Missense	distal	6	no	17.979	17.955	EPSD	COSMIC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	Q8NF50	DOCK8	P17252	PRKCA	S1080	S1077N	1077	Missense	distal	-3	no	17.979	16.622	EPSD	COSMIC	16.704	Loss
AGC_PKC_PKCa_PRKCA_ST	Q8NF50	DOCK8	P17252	PRKCA	S1080	S1080P	1080	Missense	central	0	yes	17.979	0.000	EPSD	COSMIC	16.704	Loss
AGC_PKC_PKCa_PRKCA_ST	Q8NF50	DOCK8	P17252	PRKCA	S1080	R1073T	1073	Missense	distal	-7	no	17.979	17.971	EPSD	COSMIC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	Q8NF50	DOCK8	P17252	PRKCA	S1091	I1090M	1090	Missense	proximal	-1	no	16.425	18.367	EPSD	COSMIC	16.704	Gain
AGC_PKC_PKCa_PRKCA_ST	Q8NF50	DOCK8	P17252	PRKCA	S2077	K2079Q	2079	Missense	proximal	2	no	21.009	17.597	EPSD;PhosphoSitePlus	COSMIC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	Q8NF50	DOCK8	P17252	PRKCA	S2077	R2074I	2074	Missense	distal	-3	no	21.009	16.522	EPSD;PhosphoSitePlus	COSMIC	16.704	Loss
AGC_PKC_PKCa_PRKCA_ST	Q8NF50	DOCK8	P17252	PRKCA	S2077	I2072M	2072	Missense	distal	-5	no	21.009	21.414	EPSD;PhosphoSitePlus	COSMIC	16.704	Up-regulation
AGC_PKC_PKCa_PRKCA_ST	Q8NF50	DOCK8	P17252	PRKCA	S2082	K2079Q	2079	Missense	distal	-3	no	16.915	16.083	EPSD;PhosphoSitePlus	COSMIC	16.704	Loss
AGC_PKC_PKCa_PRKCA_ST	Q15311	RALBP1	P17252	PRKCA	S116	I109N	109	Missense	distal	-7	no	20.343	20.348	EPSD	COSMIC	16.704	Up-regulation
AGC_PKC_PKCa_PRKCA_ST	Q15311	RALBP1	P17252	PRKCA	S509	E515Q	515	Missense	distal	6	no	16.726	16.710	EPSD;PhosphoSitePlus	COSMIC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	Q15311	RALBP1	P17252	PRKCA	S509	E515D	515	Missense	distal	6	no	16.726	16.743	EPSD;PhosphoSitePlus	COSMIC	16.704	Up-regulation
AGC_PKC_PKCa_PRKCA_ST	Q15311	RALBP1	P17252	PRKCA	S509	E510Q	510	Missense	proximal	1	no	16.726	18.176	EPSD;PhosphoSitePlus	COSMIC	16.704	Up-regulation
AGC_PKC_PKCa_PRKCA_ST	Q15311	RALBP1	P17252	PRKCA	S509	F502S	502	Missense	distal	-7	no	16.726	16.734	EPSD;PhosphoSitePlus	COSMIC	16.704	Up-regulation
AGC_PKC_PKCa_PRKCA_ST	Q12809	KCNH2	P17252	PRKCA	S250	A244V	244	Missense	distal	-6	no	19.574	19.497	EPSD	COSMIC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	Q12809	KCNH2	P17252	PRKCA	S283	R281S	281	Missense	proximal	-2	no	18.835	15.533	EPSD	COSMIC	16.704	Loss
AGC_PKC_PKCa_PRKCA_ST	Q12809	KCNH2	P17252	PRKCA	S283	R281C	281	Missense	proximal	-2	no	18.835	17.135	EPSD	COSMIC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	Q12809	KCNH2	P17252	PRKCA	S284	R281S	281	Missense	distal	-3	no	17.217	14.347	EPSD	COSMIC	16.704	Loss
AGC_PKC_PKCa_PRKCA_ST	Q12809	KCNH2	P17252	PRKCA	S284	R281C	281	Missense	distal	-3	no	17.217	14.478	EPSD	COSMIC	16.704	Loss
AGC_PKC_PKCa_PRKCA_ST	Q12809	KCNH2	P17252	PRKCA	S354	I359K	359	Missense	distal	5	no	17.261	17.740	EPSD	COSMIC;CCLE	16.704	Up-regulation
AGC_PKC_PKCa_PRKCA_ST	Q12809	KCNH2	P17252	PRKCA	S354	R356S	356	Missense	proximal	2	no	17.261	12.641	EPSD	COSMIC	16.704	Loss
AGC_PKC_PKCa_PRKCA_ST	Q12809	KCNH2	P17252	PRKCA	S354	P352S	352	Missense	proximal	-2	no	17.261	17.001	EPSD	COSMIC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	Q12809	KCNH2	P17252	PRKCA	S354	R356H	356	Missense	proximal	2	no	17.261	12.237	EPSD	COSMIC	16.704	Loss
AGC_PKC_PKCa_PRKCA_ST	Q12809	KCNH2	P17252	PRKCA	S882	E878K	878	Missense	distal	-4	no	17.861	18.592	EPSD	COSMIC;GDSC;CCLE	16.704	Up-regulation
AGC_PKC_PKCa_PRKCA_ST	Q12809	KCNH2	P17252	PRKCA	S882	R885C	885	Missense	distal	3	no	17.861	15.242	EPSD	COSMIC	16.704	Loss
AGC_PKC_PKCa_PRKCA_ST	Q12809	KCNH2	P17252	PRKCA	S882	R885H	885	Missense	distal	3	no	17.861	17.149	EPSD	COSMIC;GDSC;CCLE	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	Q12809	KCNH2	P17252	PRKCA	S882	R883P	883	Missense	proximal	1	no	17.861	17.086	EPSD	COSMIC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	Q12809	KCNH2	P17252	PRKCA	S882	R883Q	883	Missense	proximal	1	no	17.861	17.744	EPSD	COSMIC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	Q12809	KCNH2	P17252	PRKCA	S890	K897T	897	Missense	distal	7	no	27.532	27.442	PhosphoSitePlus	COSMIC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	Q12809	KCNH2	P17252	PRKCA	S890	R894H	894	Missense	distal	4	no	27.532	27.249	PhosphoSitePlus	COSMIC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	Q12809	KCNH2	P17252	PRKCA	S890	R885C	885	Missense	distal	-5	no	27.532	26.856	PhosphoSitePlus	COSMIC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	Q12809	KCNH2	P17252	PRKCA	S890	R885H	885	Missense	distal	-5	no	27.532	27.176	PhosphoSitePlus	COSMIC;GDSC;CCLE	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	Q12809	KCNH2	P17252	PRKCA	S890	R883P	883	Missense	distal	-7	no	27.532	27.523	PhosphoSitePlus	COSMIC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	Q12809	KCNH2	P17252	PRKCA	S890	R883Q	883	Missense	distal	-7	no	27.532	27.523	PhosphoSitePlus	COSMIC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	Q12809	KCNH2	P17252	PRKCA	S890	T895M	895	Missense	distal	5	no	27.532	27.834	PhosphoSitePlus	COSMIC;GDSC;CCLE	16.704	Up-regulation
AGC_PKC_PKCa_PRKCA_ST	Q12809	KCNH2	P17252	PRKCA	T895	K897T	897	Missense	proximal	2	no	21.854	17.465	EPSD	COSMIC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	Q12809	KCNH2	P17252	PRKCA	T895	R894H	894	Missense	proximal	-1	no	21.854	21.531	EPSD	COSMIC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	Q12809	KCNH2	P17252	PRKCA	T895	T895M	895	Missense	central	0	yes	21.854	0.000	EPSD	COSMIC;GDSC;CCLE	16.704	Loss
AGC_PKC_PKCa_PRKCA_ST	Q12809	KCNH2	P17252	PRKCA	S960	P963T	963	Missense	distal	3	no	18.190	17.884	EPSD	COSMIC;GDSC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	Q12809	KCNH2	P17252	PRKCA	S1137	L1136I	1136	Missense	proximal	-1	no	17.047	16.183	EPSD	COSMIC	16.704	Loss
AGC_PKC_PKCa_PRKCA_ST	Q12809	KCNH2	P17252	PRKCA	S1137	P1139S	1139	Missense	proximal	2	no	17.047	17.629	EPSD	COSMIC	16.704	Up-regulation
AGC_PKC_PKCa_PRKCA_ST	Q12809	KCNH2	P17252	PRKCA	S1137	G1140V	1140	Missense	distal	3	no	17.047	15.832	EPSD	COSMIC;CCLE	16.704	Loss
AGC_PKC_PKCa_PRKCA_ST	Q12809	KCNH2	P17252	PRKCA	S1137	E1130D	1130	Missense	distal	-7	no	17.047	17.050	EPSD	COSMIC	16.704	Up-regulation
AGC_PKC_PKCa_PRKCA_ST	Q12809	KCNH2	P17252	PRKCA	S1137	A1144D	1144	Missense	distal	7	no	17.047	17.051	EPSD	COSMIC	16.704	Up-regulation
AGC_PKC_PKCa_PRKCA_ST	Q99418	CYTH2	P17252	PRKCA	T276	G270W	270	Missense	distal	-6	no	21.331	21.153	EPSD	COSMIC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	Q99418	CYTH2	P17252	PRKCA	T276	T276M	276	Missense	central	0	yes	21.331	0.000	EPSD	COSMIC	16.704	Loss
AGC_PKC_PKCa_PRKCA_ST	Q99418	CYTH2	P17252	PRKCA	T276	W281L	281	Missense	distal	5	no	21.331	21.507	EPSD	COSMIC	16.704	Up-regulation
AGC_PKC_PKCa_PRKCA_ST	Q99418	CYTH2	P17252	PRKCA	T276	R273L	273	Missense	distal	-3	no	21.331	16.975	EPSD	COSMIC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	Q99418	CYTH2	P17252	PRKCA	T276	R273W	273	Missense	distal	-3	no	21.331	18.977	EPSD	COSMIC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	Q99418	CYTH2	P17252	PRKCA	T276	G272S	272	Missense	distal	-4	no	21.331	21.239	EPSD	COSMIC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	Q99418	CYTH2	P17252	PRKCA	S392	K388M	388	Missense	distal	-4	no	22.263	22.306	PhosphoSitePlus	COSMIC	16.704	Up-regulation
AGC_PKC_PKCa_PRKCA_ST	Q99418	CYTH2	P17252	PRKCA	S392	I391S	391	Missense	proximal	-1	no	22.263	23.546	PhosphoSitePlus	COSMIC	16.704	Up-regulation
AGC_PKC_PKCa_PRKCA_ST	P15336	ATF2	P17252	PRKCA	S62	I64V	64	Missense	proximal	2	no	17.530	17.548	EPSD	COSMIC	16.704	Up-regulation
AGC_PKC_PKCa_PRKCA_ST	P15336	ATF2	P17252	PRKCA	S62	R59C	59	Missense	distal	-3	no	17.530	14.791	EPSD	COSMIC	16.704	Loss
AGC_PKC_PKCa_PRKCA_ST	P15336	ATF2	P17252	PRKCA	S62	D67E	67	Missense	distal	5	no	17.530	17.622	EPSD	COSMIC	16.704	Up-regulation
AGC_PKC_PKCa_PRKCA_ST	P15336	ATF2	P17252	PRKCA	S62	G56V	56	Missense	distal	-6	no	17.530	17.450	EPSD	COSMIC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	P15336	ATF2	P17252	PRKCA	S314	Q316K	316	Missense	proximal	2	no	15.744	19.157	EPSD	COSMIC	16.704	Gain
AGC_PKC_PKCa_PRKCA_ST	P15336	ATF2	P17252	PRKCA	S314	Q317H	317	Missense	distal	3	no	15.744	17.485	EPSD	COSMIC	16.704	Gain
AGC_PKC_PKCa_PRKCA_ST	P15336	ATF2	P17252	PRKCA	S340	Q337K	337	Missense	distal	-3	no	19.248	20.080	EPSD	COSMIC	16.704	Up-regulation
AGC_PKC_PKCa_PRKCA_ST	P15336	ATF2	P17252	PRKCA	S340	Q335H	335	Missense	distal	-5	no	19.248	19.045	EPSD	COSMIC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	P15336	ATF2	P17252	PRKCA	S340	R343L	343	Missense	distal	3	no	19.248	17.011	EPSD	COSMIC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	P15336	ATF2	P17252	PRKCA	S340	P334S	334	Missense	distal	-6	no	19.248	19.280	EPSD	COSMIC	16.704	Up-regulation
AGC_PKC_PKCa_PRKCA_ST	P15336	ATF2	P17252	PRKCA	S340	R345T	345	Missense	distal	5	no	19.248	18.932	EPSD	COSMIC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	P15336	ATF2	P17252	PRKCA	S340	R343Q	343	Missense	distal	3	no	19.248	16.795	EPSD	COSMIC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	P15336	ATF2	P17252	PRKCA	S340	A347T	347	Missense	distal	7	no	19.248	19.257	EPSD	COSMIC	16.704	Up-regulation
AGC_PKC_PKCa_PRKCA_ST	P15336	ATF2	P17252	PRKCA	S340	R345K	345	Missense	distal	5	no	19.248	19.392	EPSD	COSMIC	16.704	Up-regulation
AGC_PKC_PKCa_PRKCA_ST	P15336	ATF2	P17252	PRKCA	S427	A432S	432	Missense	distal	5	no	17.317	17.214	EPSD	COSMIC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	P15336	ATF2	P17252	PRKCA	S427	T421I	421	Missense	distal	-6	no	17.317	17.345	EPSD	COSMIC	16.704	Up-regulation
AGC_PKC_PKCa_PRKCA_ST	Q9NRY4	ARHGAP35	P17252	PRKCA	S46	P45L	45	Missense	proximal	-1	no	17.404	17.284	EPSD	COSMIC;CCLE	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	Q9NRY4	ARHGAP35	P17252	PRKCA	S46	P45S	45	Missense	proximal	-1	no	17.404	17.704	EPSD	COSMIC	16.704	Up-regulation
AGC_PKC_PKCa_PRKCA_ST	Q9NRY4	ARHGAP35	P17252	PRKCA	S46	F50V	50	Missense	distal	4	no	17.404	16.444	EPSD	COSMIC	16.704	Loss
AGC_PKC_PKCa_PRKCA_ST	Q9NRY4	ARHGAP35	P17252	PRKCA	S46	C39W	39	Missense	distal	-7	no	17.404	17.406	EPSD	COSMIC	16.704	Up-regulation
AGC_PKC_PKCa_PRKCA_ST	Q9NRY4	ARHGAP35	P17252	PRKCA	S575	H572R	572	Missense	distal	-3	no	15.078	18.935	EPSD	COSMIC	16.704	Gain
AGC_PKC_PKCa_PRKCA_ST	Q9NRY4	ARHGAP35	P17252	PRKCA	S589	S589L	589	Missense	central	0	yes	16.949	0.000	EPSD	COSMIC	16.704	Loss
AGC_PKC_PKCa_PRKCA_ST	Q9NRY4	ARHGAP35	P17252	PRKCA	S589	R584Q	584	Missense	distal	-5	no	16.949	16.797	EPSD	COSMIC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	Q9NRY4	ARHGAP35	P17252	PRKCA	S684	D690Y	690	Missense	distal	6	no	18.850	18.887	EPSD	COSMIC	16.704	Up-regulation
AGC_PKC_PKCa_PRKCA_ST	Q9NRY4	ARHGAP35	P17252	PRKCA	S684	R688Q	688	Missense	distal	4	no	18.850	18.632	EPSD	COSMIC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	Q9NRY4	ARHGAP35	P17252	PRKCA	T685	D690Y	690	Missense	distal	5	no	17.614	17.861	EPSD	COSMIC	16.704	Up-regulation
AGC_PKC_PKCa_PRKCA_ST	Q9NRY4	ARHGAP35	P17252	PRKCA	T685	R688Q	688	Missense	distal	3	no	17.614	15.161	EPSD	COSMIC	16.704	Loss
AGC_PKC_PKCa_PRKCA_ST	Q9NRY4	ARHGAP35	P17252	PRKCA	S773	A778S	778	Missense	distal	5	no	17.378	17.275	EPSD	COSMIC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	Q9NRY4	ARHGAP35	P17252	PRKCA	S845	R850Q	850	Missense	distal	5	no	19.980	19.972	EPSD	COSMIC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	Q9NRY4	ARHGAP35	P17252	PRKCA	S849	R850Q	850	Missense	proximal	1	no	17.000	16.884	EPSD	COSMIC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	Q9NRY4	ARHGAP35	P17252	PRKCA	S849	H853N	853	Missense	distal	4	no	17.000	16.326	EPSD	COSMIC	16.704	Loss
AGC_PKC_PKCa_PRKCA_ST	Q9NRY4	ARHGAP35	P17252	PRKCA	S860	R863H	863	Missense	distal	3	no	16.881	16.169	EPSD	COSMIC	16.704	Loss
AGC_PKC_PKCa_PRKCA_ST	Q9NRY4	ARHGAP35	P17252	PRKCA	S860	H853N	853	Missense	distal	-7	no	16.881	16.878	EPSD	COSMIC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	Q9NRY4	ARHGAP35	P17252	PRKCA	S1070	S1070F	1070	Missense	central	0	yes	19.081	0.000	EPSD	COSMIC	16.704	Loss
AGC_PKC_PKCa_PRKCA_ST	Q9NRY4	ARHGAP35	P17252	PRKCA	S1134	G1131R	1131	Missense	distal	-3	no	13.448	16.710	EPSD	COSMIC;GDSC;CCLE	16.704	Gain
AGC_PKC_PKCa_PRKCA_ST	Q9NRY4	ARHGAP35	P17252	PRKCA	S1150	V1149I	1149	Missense	proximal	-1	no	19.515	19.695	EPSD	COSMIC	16.704	Up-regulation
AGC_PKC_PKCa_PRKCA_ST	Q9NRY4	ARHGAP35	P17252	PRKCA	S1170	A1169D	1169	Missense	proximal	-1	no	20.359	20.423	EPSD	COSMIC;GDSC;CCLE	16.704	Up-regulation
AGC_PKC_PKCa_PRKCA_ST	Q9NRY4	ARHGAP35	P17252	PRKCA	S1221	R1214W	1214	Missense	distal	-7	no	20.552	20.536	EPSD;PhosphoSitePlus	COSMIC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	Q9NRY4	ARHGAP35	P17252	PRKCA	S1221	R1214L	1214	Missense	distal	-7	no	20.552	20.542	EPSD;PhosphoSitePlus	COSMIC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	Q9NRY4	ARHGAP35	P17252	PRKCA	S1290	G1287R	1287	Missense	distal	-3	no	13.981	17.243	EPSD	COSMIC	16.704	Gain
AGC_PKC_PKCa_PRKCA_ST	P16150	SPN	P17252	PRKCA	T318	G320R	320	Missense	proximal	2	no	12.720	17.966	EPSD	COSMIC	16.704	Gain
AGC_PKC_PKCa_PRKCA_ST	P16150	SPN	P17252	PRKCA	S336	G333V	333	Missense	distal	-3	no	19.202	18.774	EPSD	COSMIC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	P16150	SPN	P17252	PRKCA	S336	P331L	331	Missense	distal	-5	no	19.202	19.176	EPSD	COSMIC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	P16150	SPN	P17252	PRKCA	S337	G333V	333	Missense	distal	-4	no	17.483	16.919	EPSD	COSMIC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	P16150	SPN	P17252	PRKCA	S337	P331L	331	Missense	distal	-6	no	17.483	17.449	EPSD	COSMIC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	P16150	SPN	P17252	PRKCA	S368	G371E	371	Missense	distal	3	no	20.566	19.967	EPSD	COSMIC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	P16150	SPN	P17252	PRKCA	S368	P375Q	375	Missense	distal	7	no	20.566	20.571	EPSD	COSMIC	16.704	Up-regulation
AGC_PKC_PKCa_PRKCA_ST	O60716	CTNND1	P17252	PRKCA	S15	A14V	14	Missense	proximal	-1	no	19.293	18.390	EPSD	COSMIC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	O60716	CTNND1	P17252	PRKCA	S15	S8L	8	Missense	distal	-7	no	19.293	19.287	EPSD	COSMIC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	O60716	CTNND1	P17252	PRKCA	S38	L41V	41	Missense	distal	3	no	16.412	16.796	EPSD	COSMIC	16.704	Gain
AGC_PKC_PKCa_PRKCA_ST	O60716	CTNND1	P17252	PRKCA	S47	V46A	46	Missense	proximal	-1	no	16.057	16.961	EPSD	COSMIC	16.704	Gain
AGC_PKC_PKCa_PRKCA_ST	O60716	CTNND1	P17252	PRKCA	S47	Q49R	49	Missense	proximal	2	no	16.057	19.891	EPSD	COSMIC	16.704	Gain
AGC_PKC_PKCa_PRKCA_ST	O60716	CTNND1	P17252	PRKCA	T61	A56T	56	Missense	distal	-5	no	17.197	17.578	EPSD	COSMIC	16.704	Up-regulation
AGC_PKC_PKCa_PRKCA_ST	O60716	CTNND1	P17252	PRKCA	T61	R62H	62	Missense	proximal	1	no	17.197	16.384	EPSD	COSMIC;GDSC;CCLE	16.704	Loss
AGC_PKC_PKCa_PRKCA_ST	O60716	CTNND1	P17252	PRKCA	T61	G58D	58	Missense	distal	-3	no	17.197	15.417	EPSD	COSMIC	16.704	Loss
AGC_PKC_PKCa_PRKCA_ST	O60716	CTNND1	P17252	PRKCA	T61	G58C	58	Missense	distal	-3	no	17.197	17.720	EPSD	COSMIC	16.704	Up-regulation
AGC_PKC_PKCa_PRKCA_ST	O60716	CTNND1	P17252	PRKCA	T61	R62S	62	Missense	proximal	1	no	17.197	16.024	EPSD	COSMIC	16.704	Loss
AGC_PKC_PKCa_PRKCA_ST	O60716	CTNND1	P17252	PRKCA	S244	R242S	242	Missense	proximal	-2	no	17.200	13.898	EPSD	COSMIC	16.704	Loss
AGC_PKC_PKCa_PRKCA_ST	O60716	CTNND1	P17252	PRKCA	S244	P251H	251	Missense	distal	7	no	17.200	17.139	EPSD	COSMIC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	O60716	CTNND1	P17252	PRKCA	S244	S244N	244	Missense	central	0	yes	17.200	0.000	EPSD	COSMIC	16.704	Loss
AGC_PKC_PKCa_PRKCA_ST	O60716	CTNND1	P17252	PRKCA	S244	R240Q	240	Missense	distal	-4	no	17.200	16.823	EPSD	COSMIC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	O60716	CTNND1	P17252	PRKCA	S244	M245L	245	Missense	proximal	1	no	17.200	17.414	EPSD	COSMIC	16.704	Up-regulation
AGC_PKC_PKCa_PRKCA_ST	O60716	CTNND1	P17252	PRKCA	T304	R306H	306	Missense	proximal	2	no	16.978	11.955	EPSD	COSMIC	16.704	Loss
AGC_PKC_PKCa_PRKCA_ST	O60716	CTNND1	P17252	PRKCA	T304	M299L	299	Missense	distal	-5	no	16.978	17.017	EPSD	COSMIC	16.704	Up-regulation
AGC_PKC_PKCa_PRKCA_ST	O60716	CTNND1	P17252	PRKCA	T304	M298V	298	Missense	distal	-6	no	16.978	16.868	EPSD	COSMIC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	O60716	CTNND1	P17252	PRKCA	T304	D301N	301	Missense	distal	-3	no	16.978	17.794	EPSD	COSMIC	16.704	Up-regulation
AGC_PKC_PKCa_PRKCA_ST	O60716	CTNND1	P17252	PRKCA	T304	G297V	297	Missense	distal	-7	no	16.978	16.974	EPSD	COSMIC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	O60716	CTNND1	P17252	PRKCA	S320	R316W	316	Missense	distal	-4	no	18.883	18.057	EPSD	COSMIC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	O60716	CTNND1	P17252	PRKCA	S320	R316L	316	Missense	distal	-4	no	18.883	18.259	EPSD	COSMIC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	O60716	CTNND1	P17252	PRKCA	S320	I325M	325	Missense	distal	5	no	18.883	19.204	EPSD	COSMIC	16.704	Up-regulation
AGC_PKC_PKCa_PRKCA_ST	O60716	CTNND1	P17252	PRKCA	S320	G326C	326	Missense	distal	6	no	18.883	18.793	EPSD	COSMIC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	O60716	CTNND1	P17252	PRKCA	S352	S352N	352	Missense	central	0	yes	20.880	0.000	EPSD	COSMIC	16.704	Loss
AGC_PKC_PKCa_PRKCA_ST	O60716	CTNND1	P17252	PRKCA	S352	S346N	346	Missense	distal	-6	no	20.880	20.823	EPSD	COSMIC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	O60716	CTNND1	P17252	PRKCA	S484	M487V	487	Missense	distal	3	no	20.140	19.554	EPSD	COSMIC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	O60716	CTNND1	P17252	PRKCA	S484	D483N	483	Missense	proximal	-1	no	20.140	20.478	EPSD	COSMIC	16.704	Up-regulation
AGC_PKC_PKCa_PRKCA_ST	O60716	CTNND1	P17252	PRKCA	S484	S484L	484	Missense	central	0	yes	20.140	0.000	EPSD	COSMIC	16.704	Loss
AGC_PKC_PKCa_PRKCA_ST	O60716	CTNND1	P17252	PRKCA	S484	V490A	490	Missense	distal	6	no	20.140	20.259	EPSD	COSMIC	16.704	Up-regulation
AGC_PKC_PKCa_PRKCA_ST	O60716	CTNND1	P17252	PRKCA	S539	N536D	536	Missense	distal	-3	no	19.007	18.192	EPSD	COSMIC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	O60716	CTNND1	P17252	PRKCA	S539	V537L	537	Missense	proximal	-2	no	19.007	19.161	EPSD	COSMIC	16.704	Up-regulation
AGC_PKC_PKCa_PRKCA_ST	O60716	CTNND1	P17252	PRKCA	S539	S542R	542	Missense	distal	3	no	19.007	20.399	EPSD	COSMIC;CCLE	16.704	Up-regulation
AGC_PKC_PKCa_PRKCA_ST	O60716	CTNND1	P17252	PRKCA	S587	Q589E	589	Missense	proximal	2	no	17.809	15.942	EPSD	COSMIC	16.704	Loss
AGC_PKC_PKCa_PRKCA_ST	O60716	CTNND1	P17252	PRKCA	S587	H591Y	591	Missense	distal	4	no	17.809	17.447	EPSD	COSMIC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	O60716	CTNND1	P17252	PRKCA	S587	R592Q	592	Missense	distal	5	no	17.809	17.800	EPSD	COSMIC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	O60716	CTNND1	P17252	PRKCA	S651	P647H	647	Missense	distal	-4	no	18.881	18.671	EPSD	COSMIC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	O60716	CTNND1	P17252	PRKCA	S651	G655C	655	Missense	distal	4	no	18.881	18.083	EPSD	COSMIC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	O60716	CTNND1	P17252	PRKCA	S651	D645Y	645	Missense	distal	-6	no	18.881	18.912	EPSD	COSMIC	16.704	Up-regulation
AGC_PKC_PKCa_PRKCA_ST	O60716	CTNND1	P17252	PRKCA	S651	L658I	658	Missense	distal	7	no	18.881	18.725	EPSD	COSMIC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	O60716	CTNND1	P17252	PRKCA	S651	L658F	658	Missense	distal	7	no	18.881	18.815	EPSD	COSMIC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	O60716	CTNND1	P17252	PRKCA	S651	L658V	658	Missense	distal	7	no	18.881	18.822	EPSD	COSMIC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	O60716	CTNND1	P17252	PRKCA	S651	R649L	649	Missense	proximal	-2	no	18.881	16.193	EPSD	COSMIC	16.704	Loss
AGC_PKC_PKCa_PRKCA_ST	O60716	CTNND1	P17252	PRKCA	S704	I702V	702	Missense	proximal	-2	no	16.479	17.225	EPSD	COSMIC	16.704	Gain
AGC_PKC_PKCa_PRKCA_ST	O60716	CTNND1	P17252	PRKCA	T799	L796R	796	Missense	distal	-3	no	13.213	17.569	EPSD	COSMIC;GDSC;CCLE	16.704	Gain
AGC_PKC_PKCa_PRKCA_ST	O60716	CTNND1	P17252	PRKCA	S879	N876Y	876	Missense	distal	-3	no	18.797	18.464	PhosphoSitePlus	COSMIC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	O60716	CTNND1	P17252	PRKCA	S879	N876S	876	Missense	distal	-3	no	18.797	20.154	PhosphoSitePlus	COSMIC	16.704	Up-regulation
AGC_PKC_PKCa_PRKCA_ST	O60716	CTNND1	P17252	PRKCA	S891	M893V	893	Missense	proximal	2	no	17.011	16.445	EPSD	COSMIC	16.704	Loss
AGC_PKC_PKCa_PRKCA_ST	Q9NQA5	TRPV5	P17252	PRKCA	S142	S144C	144	Missense	proximal	2	no	19.851	20.121	EPSD	COSMIC	16.704	Up-regulation
AGC_PKC_PKCa_PRKCA_ST	Q9NQA5	TRPV5	P17252	PRKCA	S142	S144F	144	Missense	proximal	2	no	19.851	20.168	EPSD	COSMIC	16.704	Up-regulation
AGC_PKC_PKCa_PRKCA_ST	Q9NQA5	TRPV5	P17252	PRKCA	S142	R139S	139	Missense	distal	-3	no	19.851	16.981	EPSD	COSMIC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	Q9NQA5	TRPV5	P17252	PRKCA	S155	R153L	153	Missense	proximal	-2	no	22.736	20.048	EPSD	COSMIC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	Q9NQA5	TRPV5	P17252	PRKCA	S299	R305C	305	Missense	distal	6	no	19.515	19.275	PhosphoSitePlus;EPSD	COSMIC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	Q9NQA5	TRPV5	P17252	PRKCA	S299	S298F	298	Missense	proximal	-1	no	19.515	18.807	PhosphoSitePlus;EPSD	COSMIC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	Q9NQA5	TRPV5	P17252	PRKCA	S299	L295F	295	Missense	distal	-4	no	19.515	19.887	PhosphoSitePlus;EPSD	COSMIC	16.704	Up-regulation
AGC_PKC_PKCa_PRKCA_ST	Q9NQA5	TRPV5	P17252	PRKCA	S654	E657D	657	Missense	distal	3	no	19.496	19.009	EPSD;PhosphoSitePlus	COSMIC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	P43629	KIR3DL1	P17252	PRKCA	S225	E222K	222	Missense	distal	-3	no	14.078	16.990	EPSD	COSMIC	16.704	Gain
AGC_PKC_PKCa_PRKCA_ST	P43629	KIR3DL1	P17252	PRKCA	S415	R413P	413	Missense	proximal	-2	no	19.172	16.130	PhosphoSitePlus	COSMIC	16.704	Loss
AGC_PKC_PKCa_PRKCA_ST	P43629	KIR3DL1	P17252	PRKCA	S415	R409T	409	Missense	distal	-6	no	19.172	18.973	PhosphoSitePlus	COSMIC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	P43629	KIR3DL1	P17252	PRKCA	S415	K419E	419	Missense	distal	4	no	19.172	18.633	PhosphoSitePlus	COSMIC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	P43629	KIR3DL1	P17252	PRKCA	S415	I411S	411	Missense	distal	-4	no	19.172	19.614	PhosphoSitePlus	COSMIC	16.704	Up-regulation
AGC_PKC_PKCa_PRKCA_ST	O75955	FLOT1	P17252	PRKCA	S19	V22I	22	Missense	distal	3	no	16.978	16.282	EPSD	COSMIC	16.704	Loss
AGC_PKC_PKCa_PRKCA_ST	O75955	FLOT1	P17252	PRKCA	S19	F16L	16	Missense	distal	-3	no	16.978	15.243	EPSD	COSMIC	16.704	Loss
AGC_PKC_PKCa_PRKCA_ST	O75955	FLOT1	P17252	PRKCA	S128	E129K	129	Missense	proximal	1	no	15.660	17.264	EPSD	COSMIC	16.704	Gain
AGC_PKC_PKCa_PRKCA_ST	O75955	FLOT1	P17252	PRKCA	S315	E312K	312	Missense	distal	-3	no	15.628	18.540	PhosphoSitePlus	COSMIC;GDSC;CCLE	16.704	Gain
AGC_PKC_PKCa_PRKCA_ST	Q14315	FLNC	P17252	PRKCA	S78	E75D	75	Missense	distal	-3	no	19.836	19.732	EPSD	COSMIC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	Q14315	FLNC	P17252	PRKCA	S78	R81C	81	Missense	distal	3	no	19.836	17.217	EPSD	COSMIC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	Q14315	FLNC	P17252	PRKCA	S379	R381H	381	Missense	proximal	2	no	20.058	15.035	EPSD	COSMIC	16.704	Loss
AGC_PKC_PKCa_PRKCA_ST	Q14315	FLNC	P17252	PRKCA	S379	R381C	381	Missense	proximal	2	no	20.058	15.708	EPSD	COSMIC	16.704	Loss
AGC_PKC_PKCa_PRKCA_ST	Q14315	FLNC	P17252	PRKCA	S379	A375T	375	Missense	distal	-4	no	20.058	19.310	EPSD	COSMIC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	Q14315	FLNC	P17252	PRKCA	T423	Q418H	418	Missense	distal	-5	no	17.935	17.731	EPSD	COSMIC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	Q14315	FLNC	P17252	PRKCA	S480	R482Q	482	Missense	proximal	2	no	22.448	18.614	EPSD	COSMIC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	Q14315	FLNC	P17252	PRKCA	S480	A476V	476	Missense	distal	-4	no	22.448	21.889	EPSD	COSMIC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	Q14315	FLNC	P17252	PRKCA	T909	V904A	904	Missense	distal	-5	no	18.124	18.208	EPSD	COSMIC	16.704	Up-regulation
AGC_PKC_PKCa_PRKCA_ST	Q14315	FLNC	P17252	PRKCA	T909	D903N	903	Missense	distal	-6	no	18.124	18.151	EPSD	COSMIC	16.704	Up-regulation
AGC_PKC_PKCa_PRKCA_ST	Q14315	FLNC	P17252	PRKCA	S1005	P1012S	1012	Missense	distal	7	no	19.291	19.255	EPSD	COSMIC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	Q14315	FLNC	P17252	PRKCA	S1005	D1000E	1000	Missense	distal	-5	no	19.291	19.369	EPSD	COSMIC	16.704	Up-regulation
AGC_PKC_PKCa_PRKCA_ST	Q14315	FLNC	P17252	PRKCA	S1005	V1001L	1001	Missense	distal	-4	no	19.291	19.332	EPSD	COSMIC	16.704	Up-regulation
AGC_PKC_PKCa_PRKCA_ST	Q14315	FLNC	P17252	PRKCA	S1007	P1012S	1012	Missense	distal	5	no	18.149	17.990	EPSD	COSMIC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	Q14315	FLNC	P17252	PRKCA	S1007	D1000E	1000	Missense	distal	-7	no	18.149	18.146	EPSD	COSMIC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	Q14315	FLNC	P17252	PRKCA	S1007	V1001L	1001	Missense	distal	-6	no	18.149	18.198	EPSD	COSMIC	16.704	Up-regulation
AGC_PKC_PKCa_PRKCA_ST	Q14315	FLNC	P17252	PRKCA	T1464	T1466K	1466	Missense	proximal	2	no	12.503	16.891	EPSD	COSMIC	16.704	Gain
AGC_PKC_PKCa_PRKCA_ST	Q14315	FLNC	P17252	PRKCA	T1809	R1803W	1803	Missense	distal	-6	no	17.429	17.145	EPSD	COSMIC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	Q14315	FLNC	P17252	PRKCA	T1809	R1811Q	1811	Missense	proximal	2	no	17.429	13.595	EPSD	COSMIC	16.704	Loss
AGC_PKC_PKCa_PRKCA_ST	Q14315	FLNC	P17252	PRKCA	T1809	T1815S	1815	Missense	distal	6	no	17.429	17.478	EPSD	COSMIC	16.704	Up-regulation
AGC_PKC_PKCa_PRKCA_ST	Q14315	FLNC	P17252	PRKCA	T1809	D1816N	1816	Missense	distal	7	no	17.429	17.403	EPSD	COSMIC;GDSC;CCLE	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	Q14315	FLNC	P17252	PRKCA	T1809	P1805H	1805	Missense	distal	-4	no	17.429	17.220	EPSD	COSMIC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	Q14315	FLNC	P17252	PRKCA	S1893	G1891R	1891	Missense	proximal	-2	no	14.268	17.140	EPSD	COSMIC	16.704	Gain
AGC_PKC_PKCa_PRKCA_ST	Q14315	FLNC	P17252	PRKCA	S1893	G1890R	1890	Missense	distal	-3	no	14.268	17.529	EPSD	COSMIC	16.704	Gain
AGC_PKC_PKCa_PRKCA_ST	Q14315	FLNC	P17252	PRKCA	S1980	D1973E	1973	Missense	distal	-7	no	17.169	17.166	EPSD	COSMIC;GDSC;CCLE	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	Q14315	FLNC	P17252	PRKCA	S1980	P1984S	1984	Missense	distal	4	no	17.169	17.369	EPSD	COSMIC	16.704	Up-regulation
AGC_PKC_PKCa_PRKCA_ST	Q14315	FLNC	P17252	PRKCA	S1980	L1977V	1977	Missense	distal	-3	no	17.169	17.835	EPSD	COSMIC	16.704	Up-regulation
AGC_PKC_PKCa_PRKCA_ST	Q14315	FLNC	P17252	PRKCA	S1980	A1979T	1979	Missense	proximal	-1	no	17.169	17.350	EPSD	COSMIC	16.704	Up-regulation
AGC_PKC_PKCa_PRKCA_ST	Q14315	FLNC	P17252	PRKCA	S1980	A1979V	1979	Missense	proximal	-1	no	17.169	16.266	EPSD	COSMIC	16.704	Loss
AGC_PKC_PKCa_PRKCA_ST	Q14315	FLNC	P17252	PRKCA	S2016	K2019N	2019	Missense	distal	3	no	18.009	17.062	EPSD	COSMIC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	Q14315	FLNC	P17252	PRKCA	S2016	R2018G	2018	Missense	proximal	2	no	18.009	12.764	EPSD	COSMIC	16.704	Loss
AGC_PKC_PKCa_PRKCA_ST	Q14315	FLNC	P17252	PRKCA	S2016	V2014A	2014	Missense	proximal	-2	no	18.009	17.766	EPSD	COSMIC;GDSC;CCLE	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	Q14315	FLNC	P17252	PRKCA	T2125	P2123T	2123	Missense	proximal	-2	no	17.356	17.505	EPSD	COSMIC;GDSC;CCLE	16.704	Up-regulation
AGC_PKC_PKCa_PRKCA_ST	Q14315	FLNC	P17252	PRKCA	T2125	T2129I	2129	Missense	distal	4	no	17.356	16.343	EPSD	COSMIC	16.704	Loss
AGC_PKC_PKCa_PRKCA_ST	Q14315	FLNC	P17252	PRKCA	S2137	R2140H	2140	Missense	distal	3	no	19.341	18.629	EPSD	COSMIC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	Q14315	FLNC	P17252	PRKCA	S2137	R2140C	2140	Missense	distal	3	no	19.341	16.723	EPSD	COSMIC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	Q14315	FLNC	P17252	PRKCA	S2137	R2133H	2133	Missense	distal	-4	no	19.341	18.767	EPSD	COSMIC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	Q14315	FLNC	P17252	PRKCA	S2137	R2141L	2141	Missense	distal	4	no	19.341	18.303	EPSD	COSMIC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	Q14315	FLNC	P17252	PRKCA	S2233	R2230L	2230	Missense	distal	-3	no	17.184	12.829	EPSD	COSMIC	16.704	Loss
AGC_PKC_PKCa_PRKCA_ST	Q14315	FLNC	P17252	PRKCA	S2233	R2239L	2239	Missense	distal	6	no	17.184	17.102	EPSD	COSMIC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	Q14315	FLNC	P17252	PRKCA	S2384	E2382K	2382	Missense	proximal	-2	no	14.598	17.097	EPSD	COSMIC	16.704	Gain
AGC_PKC_PKCa_PRKCA_ST	Q14315	FLNC	P17252	PRKCA	T2412	S2415L	2415	Missense	distal	3	no	18.158	17.311	EPSD	COSMIC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	Q14315	FLNC	P17252	PRKCA	T2412	R2410W	2410	Missense	proximal	-2	no	18.158	16.160	EPSD	COSMIC	16.704	Loss
AGC_PKC_PKCa_PRKCA_ST	Q14315	FLNC	P17252	PRKCA	T2412	R2409H	2409	Missense	distal	-3	no	18.158	14.301	EPSD	COSMIC	16.704	Loss
AGC_PKC_PKCa_PRKCA_ST	Q14315	FLNC	P17252	PRKCA	S2461	S2457N	2457	Missense	distal	-4	no	16.929	16.599	EPSD	COSMIC	16.704	Loss
AGC_PKC_PKCa_PRKCA_ST	Q14315	FLNC	P17252	PRKCA	S2461	K2463R	2463	Missense	proximal	2	no	16.929	17.350	EPSD	COSMIC	16.704	Up-regulation
AGC_PKC_PKCa_PRKCA_ST	Q14315	FLNC	P17252	PRKCA	S2461	H2464Y	2464	Missense	distal	3	no	16.929	15.373	EPSD	COSMIC	16.704	Loss
AGC_PKC_PKCa_PRKCA_ST	Q14315	FLNC	P17252	PRKCA	S2461	V2456I	2456	Missense	distal	-5	no	16.929	16.921	EPSD	COSMIC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	Q14315	FLNC	P17252	PRKCA	S2461	Y2455C	2455	Missense	distal	-6	no	16.929	16.686	EPSD	COSMIC	16.704	Loss
AGC_PKC_PKCa_PRKCA_ST	Q14315	FLNC	P17252	PRKCA	S2619	Y2625F	2625	Missense	distal	6	no	20.752	20.691	EPSD	COSMIC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	Q14315	FLNC	P17252	PRKCA	S2623	S2619T	2619	Missense	distal	-4	no	18.749	18.088	EPSD;PhosphoSitePlus	COSMIC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	Q14315	FLNC	P17252	PRKCA	S2623	Y2625F	2625	Missense	proximal	2	no	18.749	18.942	EPSD;PhosphoSitePlus	COSMIC	16.704	Up-regulation
AGC_PKC_PKCa_PRKCA_ST	Q14315	FLNC	P17252	PRKCA	S2624	S2619T	2619	Missense	distal	-5	no	17.410	17.737	PhosphoSitePlus;EPSD	COSMIC	16.704	Up-regulation
AGC_PKC_PKCa_PRKCA_ST	Q14315	FLNC	P17252	PRKCA	S2624	Y2625F	2625	Missense	proximal	1	no	17.410	18.083	PhosphoSitePlus;EPSD	COSMIC	16.704	Up-regulation
AGC_PKC_PKCa_PRKCA_ST	P56537	EIF6	P17252	PRKCA	S6	S6L	6	Missense	central	0	yes	16.815	0.000	EPSD	COSMIC	16.704	Loss
AGC_PKC_PKCa_PRKCA_ST	Q06124	PTPN11	P17252	PRKCA	S140	E139K	139	Missense	proximal	-1	no	17.079	17.505	EPSD	COSMIC	16.704	Up-regulation
AGC_PKC_PKCa_PRKCA_ST	Q06124	PTPN11	P17252	PRKCA	S140	G133D	133	Missense	distal	-7	no	17.079	17.078	EPSD	COSMIC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	Q06124	PTPN11	P17252	PRKCA	S140	G133C	133	Missense	distal	-7	no	17.079	17.069	EPSD	COSMIC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	Q06124	PTPN11	P17252	PRKCA	S140	R138Q	138	Missense	proximal	-2	no	17.079	15.320	EPSD	COSMIC	16.704	Loss
AGC_PKC_PKCa_PRKCA_ST	Q06124	PTPN11	P17252	PRKCA	S264	Q271E	271	Missense	distal	7	no	19.360	19.269	EPSD	COSMIC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	Q06124	PTPN11	P17252	PRKCA	S264	G268S	268	Missense	distal	4	no	19.360	19.718	EPSD	COSMIC	16.704	Up-regulation
AGC_PKC_PKCa_PRKCA_ST	Q06124	PTPN11	P17252	PRKCA	S503	M508V	508	Missense	distal	5	no	20.150	19.742	EPSD	COSMIC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	Q06124	PTPN11	P17252	PRKCA	S503	R502W	502	Missense	proximal	-1	no	20.150	18.565	EPSD	COSMIC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	Q06124	PTPN11	P17252	PRKCA	S503	S506L	506	Missense	distal	3	no	20.150	19.303	EPSD	COSMIC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	Q06124	PTPN11	P17252	PRKCA	S503	V509I	509	Missense	distal	6	no	20.150	20.205	EPSD	COSMIC	16.704	Up-regulation
AGC_PKC_PKCa_PRKCA_ST	Q06124	PTPN11	P17252	PRKCA	S503	Q504E	504	Missense	proximal	1	no	20.150	18.700	EPSD	COSMIC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	Q06124	PTPN11	P17252	PRKCA	S503	G507V	507	Missense	distal	4	no	20.150	19.186	EPSD	COSMIC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	Q06124	PTPN11	P17252	PRKCA	S503	G507R	507	Missense	distal	4	no	20.150	20.754	EPSD	COSMIC	16.704	Up-regulation
AGC_PKC_PKCa_PRKCA_ST	Q06124	PTPN11	P17252	PRKCA	S503	Q510K	510	Missense	distal	7	no	20.150	20.205	EPSD	COSMIC	16.704	Up-regulation
AGC_PKC_PKCa_PRKCA_ST	Q06124	PTPN11	P17252	PRKCA	S503	R505K	505	Missense	proximal	2	no	20.150	19.729	EPSD	COSMIC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	Q06124	PTPN11	P17252	PRKCA	S503	S506P	506	Missense	distal	3	no	20.150	20.010	EPSD	COSMIC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	Q06124	PTPN11	P17252	PRKCA	S503	G507E	507	Missense	distal	4	no	20.150	20.386	EPSD	COSMIC	16.704	Up-regulation
AGC_PKC_PKCa_PRKCA_ST	Q06124	PTPN11	P17252	PRKCA	S503	G507A	507	Missense	distal	4	no	20.150	20.524	EPSD	COSMIC	16.704	Up-regulation
AGC_PKC_PKCa_PRKCA_ST	Q06124	PTPN11	P17252	PRKCA	S503	R502Q	502	Missense	proximal	-1	no	20.150	19.333	EPSD	COSMIC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	Q06124	PTPN11	P17252	PRKCA	S503	Q510P	510	Missense	distal	7	no	20.150	20.145	EPSD	COSMIC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	Q06124	PTPN11	P17252	PRKCA	S503	G507W	507	Missense	distal	4	no	20.150	19.218	EPSD	COSMIC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	Q06124	PTPN11	P17252	PRKCA	S503	Q510E	510	Missense	distal	7	no	20.150	20.059	EPSD	COSMIC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	Q06124	PTPN11	P17252	PRKCA	S503	S506T	506	Missense	distal	3	no	20.150	19.705	EPSD	COSMIC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	Q06124	PTPN11	P17252	PRKCA	S503	S506A	506	Missense	distal	3	no	20.150	19.944	EPSD	COSMIC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	Q06124	PTPN11	P17252	PRKCA	S503	R502L	502	Missense	proximal	-1	no	20.150	19.343	EPSD	COSMIC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	Q06124	PTPN11	P17252	PRKCA	S503	T497I	497	Missense	distal	-6	no	20.150	20.179	EPSD	COSMIC	16.704	Up-regulation
AGC_PKC_PKCa_PRKCA_ST	Q06124	PTPN11	P17252	PRKCA	S503	M508I	508	Missense	distal	5	no	20.150	19.829	EPSD	COSMIC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	Q06124	PTPN11	P17252	PRKCA	S503	G507L	507	Missense	distal	4	no	20.150	19.715	EPSD	COSMIC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	Q06124	PTPN11	P17252	PRKCA	S503	S503F	503	Missense	central	0	yes	20.150	0.000	EPSD	COSMIC	16.704	Loss
AGC_PKC_PKCa_PRKCA_ST	Q06124	PTPN11	P17252	PRKCA	S539	E545K	545	Missense	distal	6	no	17.674	17.768	EPSD	COSMIC	16.704	Up-regulation
AGC_PKC_PKCa_PRKCA_ST	Q06124	PTPN11	P17252	PRKCA	S539	E545D	545	Missense	distal	6	no	17.674	17.691	EPSD	COSMIC	16.704	Up-regulation
AGC_PKC_PKCa_PRKCA_ST	Q06124	PTPN11	P17252	PRKCA	S539	I533V	533	Missense	distal	-6	no	17.674	17.658	EPSD	COSMIC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	Q06124	PTPN11	P17252	PRKCA	S539	Y546C	546	Missense	distal	7	no	17.674	17.503	EPSD	COSMIC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	Q06124	PTPN11	P17252	PRKCA	S539	G543E	543	Missense	distal	4	no	17.674	17.910	EPSD	COSMIC	16.704	Up-regulation
AGC_PKC_PKCa_PRKCA_ST	Q06124	PTPN11	P17252	PRKCA	S580	D579E	579	Missense	proximal	-1	no	17.475	17.989	EPSD	COSMIC	16.704	Up-regulation
AGC_PKC_PKCa_PRKCA_ST	Q06124	PTPN11	P17252	PRKCA	S580	R582G	582	Missense	proximal	2	no	17.475	12.230	EPSD	COSMIC	16.704	Loss
AGC_PKC_PKCa_PRKCA_ST	Q06124	PTPN11	P17252	PRKCA	S580	V583A	583	Missense	distal	3	no	17.475	17.732	EPSD	COSMIC	16.704	Up-regulation
AGC_PKC_PKCa_PRKCA_ST	Q06124	PTPN11	P17252	PRKCA	S580	V587A	587	Missense	distal	7	no	17.475	17.530	EPSD	COSMIC	16.704	Up-regulation
AGC_PKC_PKCa_PRKCA_ST	Q06124	PTPN11	P17252	PRKCA	S580	S580I	580	Missense	central	0	yes	17.475	0.000	EPSD	COSMIC	16.704	Loss
AGC_PKC_PKCa_PRKCA_ST	Q06124	PTPN11	P17252	PRKCA	S595	Q592H	592	Missense	distal	-3	no	17.166	16.167	EPSD	COSMIC	16.704	Loss
AGC_PKC_PKCa_PRKCA_ST	Q06124	PTPN11	P17252	PRKCA	S595	K594R	594	Missense	proximal	-1	no	17.166	17.109	EPSD	COSMIC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	Q14432	PDE3A	P17252	PRKCA	S292	E299K	299	Missense	distal	7	no	18.649	18.795	PhosphoSitePlus;EPSD	COSMIC	16.704	Up-regulation
AGC_PKC_PKCa_PRKCA_ST	Q14432	PDE3A	P17252	PRKCA	S292	A298T	298	Missense	distal	6	no	18.649	18.571	PhosphoSitePlus;EPSD	COSMIC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	Q14432	PDE3A	P17252	PRKCA	S292	R289G	289	Missense	distal	-3	no	18.649	15.387	PhosphoSitePlus;EPSD	COSMIC	16.704	Loss
AGC_PKC_PKCa_PRKCA_ST	Q14432	PDE3A	P17252	PRKCA	S292	S293G	293	Missense	proximal	1	no	18.649	18.869	PhosphoSitePlus;EPSD	COSMIC	16.704	Up-regulation
AGC_PKC_PKCa_PRKCA_ST	Q14432	PDE3A	P17252	PRKCA	S293	E299K	299	Missense	distal	6	no	20.161	20.255	EPSD;PhosphoSitePlus	COSMIC	16.704	Up-regulation
AGC_PKC_PKCa_PRKCA_ST	Q14432	PDE3A	P17252	PRKCA	S293	A298T	298	Missense	distal	5	no	20.161	19.882	EPSD;PhosphoSitePlus	COSMIC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	Q14432	PDE3A	P17252	PRKCA	S293	R289G	289	Missense	distal	-4	no	20.161	20.059	EPSD;PhosphoSitePlus	COSMIC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	Q14432	PDE3A	P17252	PRKCA	S293	S293G	293	Missense	central	0	yes	20.161	0.000	EPSD;PhosphoSitePlus	COSMIC	16.704	Loss
AGC_PKC_PKCa_PRKCA_ST	Q14432	PDE3A	P17252	PRKCA	S294	E299K	299	Missense	distal	5	no	17.739	18.153	EPSD	COSMIC	16.704	Up-regulation
AGC_PKC_PKCa_PRKCA_ST	Q14432	PDE3A	P17252	PRKCA	S294	A298T	298	Missense	distal	4	no	17.739	17.292	EPSD	COSMIC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	Q14432	PDE3A	P17252	PRKCA	S294	R289G	289	Missense	distal	-5	no	17.739	17.449	EPSD	COSMIC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	Q14432	PDE3A	P17252	PRKCA	S294	S293G	293	Missense	proximal	-1	no	17.739	17.987	EPSD	COSMIC	16.704	Up-regulation
AGC_PKC_PKCa_PRKCA_ST	Q14432	PDE3A	P17252	PRKCA	S297	E299K	299	Missense	proximal	2	no	12.906	18.186	EPSD	COSMIC	16.704	Gain
AGC_PKC_PKCa_PRKCA_ST	Q14432	PDE3A	P17252	PRKCA	S304	E299K	299	Missense	distal	-5	no	17.721	18.015	EPSD	COSMIC	16.704	Up-regulation
AGC_PKC_PKCa_PRKCA_ST	Q14432	PDE3A	P17252	PRKCA	S304	R309Q	309	Missense	distal	5	no	17.721	17.713	EPSD	COSMIC;GDSC;CCLE	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	Q14432	PDE3A	P17252	PRKCA	S304	H308N	308	Missense	distal	4	no	17.721	17.047	EPSD	COSMIC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	Q14432	PDE3A	P17252	PRKCA	S304	A298T	298	Missense	distal	-6	no	17.721	17.633	EPSD	COSMIC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	Q14432	PDE3A	P17252	PRKCA	S305	E299K	299	Missense	distal	-6	no	17.664	17.731	EPSD	COSMIC	16.704	Up-regulation
AGC_PKC_PKCa_PRKCA_ST	Q14432	PDE3A	P17252	PRKCA	S305	R309Q	309	Missense	distal	4	no	17.664	17.446	EPSD	COSMIC;GDSC;CCLE	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	Q14432	PDE3A	P17252	PRKCA	S305	H308N	308	Missense	distal	3	no	17.664	16.806	EPSD	COSMIC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	Q14432	PDE3A	P17252	PRKCA	S305	A298T	298	Missense	distal	-7	no	17.664	17.659	EPSD	COSMIC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	Q14432	PDE3A	P17252	PRKCA	S312	I316M	316	Missense	distal	4	no	16.134	17.629	EPSD;PhosphoSitePlus	COSMIC;GDSC;CCLE	16.704	Gain
AGC_PKC_PKCa_PRKCA_ST	Q14432	PDE3A	P17252	PRKCA	S312	C315F	315	Missense	distal	3	no	16.134	16.848	EPSD;PhosphoSitePlus	COSMIC;GDSC;CCLE	16.704	Gain
AGC_PKC_PKCa_PRKCA_ST	Q14432	PDE3A	P17252	PRKCA	S463	S465G	465	Missense	proximal	2	no	16.813	16.188	EPSD	COSMIC	16.704	Loss
AGC_PKC_PKCa_PRKCA_ST	Q14432	PDE3A	P17252	PRKCA	S463	R462C	462	Missense	proximal	-1	no	16.813	14.153	EPSD	COSMIC;GDSC	16.704	Loss
AGC_PKC_PKCa_PRKCA_ST	Q14432	PDE3A	P17252	PRKCA	S465	S465G	465	Missense	central	0	yes	21.436	0.000	EPSD;PhosphoSitePlus	COSMIC	16.704	Loss
AGC_PKC_PKCa_PRKCA_ST	Q14432	PDE3A	P17252	PRKCA	S465	R462C	462	Missense	distal	-3	no	21.436	18.696	EPSD;PhosphoSitePlus	COSMIC;GDSC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	Q14432	PDE3A	P17252	PRKCA	S511	R512L	512	Missense	proximal	1	no	18.953	18.605	EPSD	COSMIC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	Q14432	PDE3A	P17252	PRKCA	S511	V505I	505	Missense	distal	-6	no	18.953	18.969	EPSD	COSMIC	16.704	Up-regulation
AGC_PKC_PKCa_PRKCA_ST	Q14432	PDE3A	P17252	PRKCA	S511	K508I	508	Missense	distal	-3	no	18.953	16.491	EPSD	COSMIC	16.704	Loss
AGC_PKC_PKCa_PRKCA_ST	Q14432	PDE3A	P17252	PRKCA	S528	P525R	525	Missense	distal	-3	no	13.005	16.854	EPSD	COSMIC	16.704	Gain
AGC_PKC_PKCa_PRKCA_ST	Q14432	PDE3A	P17252	PRKCA	S561	T568S	568	Missense	distal	7	no	17.658	17.651	EPSD	COSMIC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	Q14432	PDE3A	P17252	PRKCA	S593	C588Y	588	Missense	distal	-5	no	17.099	17.266	EPSD	COSMIC	16.704	Up-regulation
AGC_PKC_PKCa_PRKCA_ST	Q14432	PDE3A	P17252	PRKCA	S593	D599N	599	Missense	distal	6	no	17.099	17.015	EPSD	COSMIC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	Q14432	PDE3A	P17252	PRKCA	S593	S587I	587	Missense	distal	-6	no	17.099	17.002	EPSD	COSMIC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	Q14432	PDE3A	P17252	PRKCA	S593	S587R	587	Missense	distal	-6	no	17.099	17.173	EPSD	COSMIC	16.704	Up-regulation
AGC_PKC_PKCa_PRKCA_ST	Q14432	PDE3A	P17252	PRKCA	S593	C588S	588	Missense	distal	-5	no	17.099	17.348	EPSD	COSMIC;GDSC	16.704	Up-regulation
AGC_PKC_PKCa_PRKCA_ST	Q14432	PDE3A	P17252	PRKCA	S593	G595E	595	Missense	proximal	2	no	17.099	16.644	EPSD	COSMIC	16.704	Loss
AGC_PKC_PKCa_PRKCA_ST	Q14432	PDE3A	P17252	PRKCA	S654	A660V	660	Missense	distal	6	no	19.438	19.319	EPSD	COSMIC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	Q14432	PDE3A	P17252	PRKCA	S654	A653P	653	Missense	proximal	-1	no	19.438	19.697	EPSD	COSMIC	16.704	Up-regulation
AGC_PKC_PKCa_PRKCA_ST	Q14432	PDE3A	P17252	PRKCA	S654	P661S	661	Missense	distal	7	no	19.438	19.402	EPSD	COSMIC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	Q14432	PDE3A	P17252	PRKCA	S1060	S1060F	1060	Missense	central	0	yes	17.940	0.000	EPSD	COSMIC	16.704	Loss
AGC_PKC_PKCa_PRKCA_ST	Q14432	PDE3A	P17252	PRKCA	S1060	K1063N	1063	Missense	distal	3	no	17.940	16.992	EPSD	COSMIC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	P16671	CD36	P17252	PRKCA	T92	Q87R	87	Missense	distal	-5	no	16.658	16.810	PhosphoSitePlus	COSMIC;GDSC;CCLE	16.704	Gain
AGC_PKC_PKCa_PRKCA_ST	Q8WZ42	TTN	P17252	PRKCA	S57	S59R	59	Missense	proximal	2	no	16.136	20.756	EPSD	COSMIC	16.704	Gain
AGC_PKC_PKCa_PRKCA_ST	Q8WZ42	TTN	P17252	PRKCA	S79	G85E	85	Missense	distal	6	no	20.202	20.245	EPSD	COSMIC	16.704	Up-regulation
AGC_PKC_PKCa_PRKCA_ST	Q8WZ42	TTN	P17252	PRKCA	S112	R109G	109	Missense	distal	-3	no	17.735	14.474	EPSD	COSMIC	16.704	Loss
AGC_PKC_PKCa_PRKCA_ST	Q8WZ42	TTN	P17252	PRKCA	S112	G118E	118	Missense	distal	6	no	17.735	17.778	EPSD	COSMIC	16.704	Up-regulation
AGC_PKC_PKCa_PRKCA_ST	Q8WZ42	TTN	P17252	PRKCA	S112	Q108E	108	Missense	distal	-4	no	17.735	17.417	EPSD	COSMIC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	Q8WZ42	TTN	P17252	PRKCA	S112	Q111H	111	Missense	proximal	-1	no	17.735	18.230	EPSD	COSMIC	16.704	Up-regulation
AGC_PKC_PKCa_PRKCA_ST	Q8WZ42	TTN	P17252	PRKCA	S320	V321L	321	Missense	proximal	1	no	18.268	18.143	EPSD	COSMIC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	Q8WZ42	TTN	P17252	PRKCA	S320	L326I	326	Missense	distal	6	no	18.268	18.245	EPSD	COSMIC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	Q8WZ42	TTN	P17252	PRKCA	S320	M327I	327	Missense	distal	7	no	18.268	18.104	EPSD	COSMIC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	Q8WZ42	TTN	P17252	PRKCA	T330	V335M	335	Missense	distal	5	no	16.940	17.348	EPSD	COSMIC	16.704	Up-regulation
AGC_PKC_PKCa_PRKCA_ST	Q8WZ42	TTN	P17252	PRKCA	T330	T334A	334	Missense	distal	4	no	16.940	17.387	EPSD	COSMIC	16.704	Up-regulation
AGC_PKC_PKCa_PRKCA_ST	Q8WZ42	TTN	P17252	PRKCA	T330	L326I	326	Missense	distal	-4	no	16.940	16.929	EPSD	COSMIC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	Q8WZ42	TTN	P17252	PRKCA	T330	M327I	327	Missense	distal	-3	no	16.940	15.425	EPSD	COSMIC	16.704	Loss
AGC_PKC_PKCa_PRKCA_ST	Q8WZ42	TTN	P17252	PRKCA	S813	V818M	818	Missense	distal	5	no	17.059	17.467	EPSD	COSMIC	16.704	Up-regulation
AGC_PKC_PKCa_PRKCA_ST	Q8WZ42	TTN	P17252	PRKCA	S813	D806N	806	Missense	distal	-7	no	17.059	17.058	EPSD	COSMIC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	Q8WZ42	TTN	P17252	PRKCA	S813	P814H	814	Missense	proximal	1	no	17.059	17.020	EPSD	COSMIC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	Q8WZ42	TTN	P17252	PRKCA	S847	E845K	845	Missense	proximal	-2	no	15.167	17.666	EPSD	COSMIC	16.704	Gain
AGC_PKC_PKCa_PRKCA_ST	Q8WZ42	TTN	P17252	PRKCA	T863	T856A	856	Missense	distal	-7	no	17.979	17.983	EPSD	COSMIC	16.704	Up-regulation
AGC_PKC_PKCa_PRKCA_ST	Q8WZ42	TTN	P17252	PRKCA	T863	S858L	858	Missense	distal	-5	no	17.979	18.278	EPSD	COSMIC	16.704	Up-regulation
AGC_PKC_PKCa_PRKCA_ST	Q8WZ42	TTN	P17252	PRKCA	S1348	P1352L	1352	Missense	distal	4	no	20.626	20.033	EPSD	COSMIC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	Q8WZ42	TTN	P17252	PRKCA	S1348	V1353G	1353	Missense	distal	5	no	20.626	20.767	EPSD	COSMIC	16.704	Up-regulation
AGC_PKC_PKCa_PRKCA_ST	Q8WZ42	TTN	P17252	PRKCA	S1404	L1405P	1405	Missense	proximal	1	no	17.414	16.987	EPSD	COSMIC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	Q8WZ42	TTN	P17252	PRKCA	S1404	R1408C	1408	Missense	distal	4	no	17.414	16.013	EPSD	COSMIC	16.704	Loss
AGC_PKC_PKCa_PRKCA_ST	Q8WZ42	TTN	P17252	PRKCA	S1406	L1405P	1405	Missense	proximal	-1	no	19.618	19.737	EPSD	COSMIC	16.704	Up-regulation
AGC_PKC_PKCa_PRKCA_ST	Q8WZ42	TTN	P17252	PRKCA	S1406	S1413F	1413	Missense	distal	7	no	19.618	19.554	EPSD	COSMIC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	Q8WZ42	TTN	P17252	PRKCA	S1406	R1408C	1408	Missense	proximal	2	no	19.618	15.267	EPSD	COSMIC	16.704	Loss
AGC_PKC_PKCa_PRKCA_ST	Q8WZ42	TTN	P17252	PRKCA	S1409	R1416C	1416	Missense	distal	7	no	16.932	16.708	EPSD	COSMIC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	Q8WZ42	TTN	P17252	PRKCA	S1409	L1405P	1405	Missense	distal	-4	no	16.932	17.191	EPSD	COSMIC	16.704	Up-regulation
AGC_PKC_PKCa_PRKCA_ST	Q8WZ42	TTN	P17252	PRKCA	S1409	S1413F	1413	Missense	distal	4	no	16.932	16.570	EPSD	COSMIC	16.704	Loss
AGC_PKC_PKCa_PRKCA_ST	Q8WZ42	TTN	P17252	PRKCA	S1409	R1408C	1408	Missense	proximal	-1	no	16.932	14.272	EPSD	COSMIC	16.704	Loss
AGC_PKC_PKCa_PRKCA_ST	Q8WZ42	TTN	P17252	PRKCA	S1418	R1416C	1416	Missense	proximal	-2	no	19.132	17.432	EPSD	COSMIC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	Q8WZ42	TTN	P17252	PRKCA	S1418	S1413F	1413	Missense	distal	-5	no	19.132	19.235	EPSD	COSMIC	16.704	Up-regulation
AGC_PKC_PKCa_PRKCA_ST	Q8WZ42	TTN	P17252	PRKCA	S1418	R1421W	1421	Missense	distal	3	no	19.132	16.198	EPSD	COSMIC	16.704	Loss
AGC_PKC_PKCa_PRKCA_ST	Q8WZ42	TTN	P17252	PRKCA	S1423	R1416C	1416	Missense	distal	-7	no	17.149	17.130	EPSD	COSMIC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	Q8WZ42	TTN	P17252	PRKCA	S1423	P1429L	1429	Missense	distal	6	no	17.149	17.105	EPSD	COSMIC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	Q8WZ42	TTN	P17252	PRKCA	S1423	R1421W	1421	Missense	proximal	-2	no	17.149	15.151	EPSD	COSMIC	16.704	Loss
AGC_PKC_PKCa_PRKCA_ST	Q8WZ42	TTN	P17252	PRKCA	S1428	P1429L	1429	Missense	proximal	1	no	19.125	19.552	EPSD	COSMIC	16.704	Up-regulation
AGC_PKC_PKCa_PRKCA_ST	Q8WZ42	TTN	P17252	PRKCA	S1428	P1434S	1434	Missense	distal	6	no	19.125	19.092	EPSD	COSMIC;CCLE	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	Q8WZ42	TTN	P17252	PRKCA	S1428	R1431Q	1431	Missense	distal	3	no	19.125	16.672	EPSD	COSMIC	16.704	Loss
AGC_PKC_PKCa_PRKCA_ST	Q8WZ42	TTN	P17252	PRKCA	S1428	S1433P	1433	Missense	distal	5	no	19.125	19.284	EPSD	COSMIC	16.704	Up-regulation
AGC_PKC_PKCa_PRKCA_ST	Q8WZ42	TTN	P17252	PRKCA	S1428	R1421W	1421	Missense	distal	-7	no	19.125	19.108	EPSD	COSMIC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	Q8WZ42	TTN	P17252	PRKCA	S1433	P1429L	1429	Missense	distal	-4	no	17.000	16.740	EPSD	COSMIC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	Q8WZ42	TTN	P17252	PRKCA	S1433	P1434S	1434	Missense	proximal	1	no	17.000	16.600	EPSD	COSMIC;CCLE	16.704	Loss
AGC_PKC_PKCa_PRKCA_ST	Q8WZ42	TTN	P17252	PRKCA	S1433	R1431Q	1431	Missense	proximal	-2	no	17.000	15.241	EPSD	COSMIC	16.704	Loss
AGC_PKC_PKCa_PRKCA_ST	Q8WZ42	TTN	P17252	PRKCA	S1433	S1433P	1433	Missense	central	0	yes	17.000	0.000	EPSD	COSMIC	16.704	Loss
AGC_PKC_PKCa_PRKCA_ST	Q8WZ42	TTN	P17252	PRKCA	S1438	P1434S	1434	Missense	distal	-4	no	16.537	16.708	EPSD	COSMIC;CCLE	16.704	Gain
AGC_PKC_PKCa_PRKCA_ST	Q8WZ42	TTN	P17252	PRKCA	S1438	S1433P	1433	Missense	distal	-5	no	16.537	16.862	EPSD	COSMIC	16.704	Gain
AGC_PKC_PKCa_PRKCA_ST	Q8WZ42	TTN	P17252	PRKCA	S1540	I1541T	1541	Missense	proximal	1	no	18.905	17.569	EPSD	COSMIC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	Q8WZ42	TTN	P17252	PRKCA	S1540	I1544V	1544	Missense	distal	4	no	18.905	19.028	EPSD	COSMIC	16.704	Up-regulation
AGC_PKC_PKCa_PRKCA_ST	Q8WZ42	TTN	P17252	PRKCA	S1540	R1538K	1538	Missense	proximal	-2	no	18.905	17.277	EPSD	COSMIC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	Q8WZ42	TTN	P17252	PRKCA	S1540	G1537C	1537	Missense	distal	-3	no	18.905	19.427	EPSD	COSMIC;CCLE	16.704	Up-regulation
AGC_PKC_PKCa_PRKCA_ST	Q8WZ42	TTN	P17252	PRKCA	S1571	E1569K	1569	Missense	proximal	-2	no	14.487	16.986	EPSD	COSMIC	16.704	Gain
AGC_PKC_PKCa_PRKCA_ST	Q8WZ42	TTN	P17252	PRKCA	T1609	G1611R	1611	Missense	proximal	2	no	11.635	16.880	EPSD	COSMIC	16.704	Gain
AGC_PKC_PKCa_PRKCA_ST	Q8WZ42	TTN	P17252	PRKCA	S2086	I2084M	2084	Missense	proximal	-2	no	15.396	17.003	EPSD	COSMIC	16.704	Gain
AGC_PKC_PKCa_PRKCA_ST	Q8WZ42	TTN	P17252	PRKCA	T2315	S2316F	2316	Missense	proximal	1	no	15.617	17.101	EPSD	COSMIC	16.704	Gain
AGC_PKC_PKCa_PRKCA_ST	Q8WZ42	TTN	P17252	PRKCA	S2316	R2320H	2320	Missense	distal	4	no	18.161	17.879	EPSD	COSMIC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	Q8WZ42	TTN	P17252	PRKCA	S2316	S2316F	2316	Missense	central	0	yes	18.161	0.000	EPSD	COSMIC	16.704	Loss
AGC_PKC_PKCa_PRKCA_ST	Q8WZ42	TTN	P17252	PRKCA	S2316	Q2321K	2321	Missense	distal	5	no	18.161	18.314	EPSD	COSMIC	16.704	Up-regulation
AGC_PKC_PKCa_PRKCA_ST	Q8WZ42	TTN	P17252	PRKCA	S2316	R2318G	2318	Missense	proximal	2	no	18.161	12.916	EPSD	COSMIC	16.704	Loss
AGC_PKC_PKCa_PRKCA_ST	Q8WZ42	TTN	P17252	PRKCA	S2398	H2402Y	2402	Missense	distal	4	no	16.997	16.635	EPSD	COSMIC	16.704	Loss
AGC_PKC_PKCa_PRKCA_ST	Q8WZ42	TTN	P17252	PRKCA	S2398	D2391N	2391	Missense	distal	-7	no	16.997	16.996	EPSD	COSMIC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	Q8WZ42	TTN	P17252	PRKCA	S2398	I2403F	2403	Missense	distal	5	no	16.997	17.224	EPSD	COSMIC	16.704	Up-regulation
AGC_PKC_PKCa_PRKCA_ST	Q8WZ42	TTN	P17252	PRKCA	S2398	Q2393L	2393	Missense	distal	-5	no	16.997	17.021	EPSD	COSMIC;GDSC;CCLE	16.704	Up-regulation
AGC_PKC_PKCa_PRKCA_ST	Q8WZ42	TTN	P17252	PRKCA	S2437	R2439H	2439	Missense	proximal	2	no	17.226	12.202	EPSD	COSMIC	16.704	Loss
AGC_PKC_PKCa_PRKCA_ST	Q8WZ42	TTN	P17252	PRKCA	S2510	E2512K	2512	Missense	proximal	2	no	11.879	17.158	EPSD	COSMIC	16.704	Gain
AGC_PKC_PKCa_PRKCA_ST	Q8WZ42	TTN	P17252	PRKCA	S2612	E2608K	2608	Missense	distal	-4	no	16.096	16.827	EPSD	COSMIC	16.704	Gain
AGC_PKC_PKCa_PRKCA_ST	Q8WZ42	TTN	P17252	PRKCA	S2763	R2765G	2765	Missense	proximal	2	no	17.684	12.439	EPSD	COSMIC	16.704	Loss
AGC_PKC_PKCa_PRKCA_ST	Q8WZ42	TTN	P17252	PRKCA	S2763	K2767E	2767	Missense	distal	4	no	17.684	17.145	EPSD	COSMIC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	Q8WZ42	TTN	P17252	PRKCA	S2763	G2759E	2759	Missense	distal	-4	no	17.684	17.090	EPSD	COSMIC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	Q8WZ42	TTN	P17252	PRKCA	S2763	G2759S	2759	Missense	distal	-4	no	17.684	17.592	EPSD	COSMIC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	Q8WZ42	TTN	P17252	PRKCA	S3118	R3120Q	3120	Missense	proximal	2	no	16.900	13.066	EPSD	COSMIC	16.704	Loss
AGC_PKC_PKCa_PRKCA_ST	Q8WZ42	TTN	P17252	PRKCA	S3118	L3114I	3114	Missense	distal	-4	no	16.900	16.889	EPSD	COSMIC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	Q8WZ42	TTN	P17252	PRKCA	S3118	D3123H	3123	Missense	distal	5	no	16.900	17.002	EPSD	COSMIC	16.704	Up-regulation
AGC_PKC_PKCa_PRKCA_ST	Q8WZ42	TTN	P17252	PRKCA	S3118	I3116M	3116	Missense	proximal	-2	no	16.900	18.506	EPSD	COSMIC	16.704	Up-regulation
AGC_PKC_PKCa_PRKCA_ST	Q8WZ42	TTN	P17252	PRKCA	S3122	D3123H	3123	Missense	proximal	1	no	16.446	17.232	EPSD	COSMIC	16.704	Gain
AGC_PKC_PKCa_PRKCA_ST	Q8WZ42	TTN	P17252	PRKCA	S3252	T3249M	3249	Missense	distal	-3	no	16.223	17.415	EPSD	COSMIC	16.704	Gain
AGC_PKC_PKCa_PRKCA_ST	Q8WZ42	TTN	P17252	PRKCA	S3594	G3596R	3596	Missense	proximal	2	no	13.443	18.688	EPSD	COSMIC	16.704	Gain
AGC_PKC_PKCa_PRKCA_ST	Q8WZ42	TTN	P17252	PRKCA	S4010	V4003A	4003	Missense	distal	-7	no	17.516	17.526	EPSD	COSMIC	16.704	Up-regulation
AGC_PKC_PKCa_PRKCA_ST	Q8WZ42	TTN	P17252	PRKCA	S4010	R4012M	4012	Missense	proximal	2	no	17.516	13.068	EPSD	COSMIC	16.704	Loss
AGC_PKC_PKCa_PRKCA_ST	Q8WZ42	TTN	P17252	PRKCA	S4185	Q4187R	4187	Missense	proximal	2	no	14.613	18.448	EPSD	COSMIC	16.704	Gain
AGC_PKC_PKCa_PRKCA_ST	Q8WZ42	TTN	P17252	PRKCA	S4196	E4200K	4200	Missense	distal	4	no	18.347	18.886	EPSD	COSMIC	16.704	Up-regulation
AGC_PKC_PKCa_PRKCA_ST	Q8WZ42	TTN	P17252	PRKCA	S4196	F4193L	4193	Missense	distal	-3	no	18.347	16.612	EPSD	COSMIC	16.704	Loss
AGC_PKC_PKCa_PRKCA_ST	Q8WZ42	TTN	P17252	PRKCA	S4196	E4200D	4200	Missense	distal	4	no	18.347	18.116	EPSD	COSMIC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	Q8WZ42	TTN	P17252	PRKCA	S4196	S4196C	4196	Missense	central	0	yes	18.347	0.000	EPSD	COSMIC	16.704	Loss
AGC_PKC_PKCa_PRKCA_ST	Q8WZ42	TTN	P17252	PRKCA	S4430	I4437T	4437	Missense	distal	7	no	17.744	17.904	EPSD	COSMIC	16.704	Up-regulation
AGC_PKC_PKCa_PRKCA_ST	Q8WZ42	TTN	P17252	PRKCA	S4430	I4437M	4437	Missense	distal	7	no	17.744	17.908	EPSD	COSMIC	16.704	Up-regulation
AGC_PKC_PKCa_PRKCA_ST	Q8WZ42	TTN	P17252	PRKCA	S4430	Y4436N	4436	Missense	distal	6	no	17.744	17.622	EPSD	COSMIC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	Q8WZ42	TTN	P17252	PRKCA	S4486	T4489A	4489	Missense	distal	3	no	18.333	18.572	EPSD	COSMIC;GDSC	16.704	Up-regulation
AGC_PKC_PKCa_PRKCA_ST	Q8WZ42	TTN	P17252	PRKCA	S4486	T4489M	4489	Missense	distal	3	no	18.333	18.902	EPSD	COSMIC;GDSC	16.704	Up-regulation
AGC_PKC_PKCa_PRKCA_ST	Q8WZ42	TTN	P17252	PRKCA	S4486	R4483K	4483	Missense	distal	-3	no	18.333	16.307	EPSD	COSMIC	16.704	Loss
AGC_PKC_PKCa_PRKCA_ST	Q8WZ42	TTN	P17252	PRKCA	S4486	R4483G	4483	Missense	distal	-3	no	18.333	15.072	EPSD	COSMIC	16.704	Loss
AGC_PKC_PKCa_PRKCA_ST	Q8WZ42	TTN	P17252	PRKCA	S4527	D4528Y	4528	Missense	proximal	1	no	17.126	18.363	EPSD	COSMIC	16.704	Up-regulation
AGC_PKC_PKCa_PRKCA_ST	Q8WZ42	TTN	P17252	PRKCA	S4527	P4520S	4520	Missense	distal	-7	no	17.126	17.129	EPSD	COSMIC	16.704	Up-regulation
AGC_PKC_PKCa_PRKCA_ST	Q8WZ42	TTN	P17252	PRKCA	S4527	R4525W	4525	Missense	proximal	-2	no	17.126	15.129	EPSD	COSMIC	16.704	Loss
AGC_PKC_PKCa_PRKCA_ST	Q8WZ42	TTN	P17252	PRKCA	S4549	I4542V	4542	Missense	distal	-7	no	17.003	17.004	EPSD	COSMIC	16.704	Up-regulation
AGC_PKC_PKCa_PRKCA_ST	Q8WZ42	TTN	P17252	PRKCA	S4549	K4551N	4551	Missense	proximal	2	no	17.003	12.054	EPSD	COSMIC	16.704	Loss
AGC_PKC_PKCa_PRKCA_ST	Q8WZ42	TTN	P17252	PRKCA	S4549	D4544E	4544	Missense	distal	-5	no	17.003	17.081	EPSD	COSMIC	16.704	Up-regulation
AGC_PKC_PKCa_PRKCA_ST	Q8WZ42	TTN	P17252	PRKCA	S4553	K4551N	4551	Missense	proximal	-2	no	19.626	18.058	EPSD	COSMIC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	Q8WZ42	TTN	P17252	PRKCA	S4553	G4557E	4557	Missense	distal	4	no	19.626	19.862	EPSD	COSMIC	16.704	Up-regulation
AGC_PKC_PKCa_PRKCA_ST	Q8WZ42	TTN	P17252	PRKCA	S4987	K4988I	4988	Missense	proximal	1	no	18.125	18.577	EPSD	COSMIC	16.704	Up-regulation
AGC_PKC_PKCa_PRKCA_ST	Q8WZ42	TTN	P17252	PRKCA	S4987	S4993G	4993	Missense	distal	6	no	18.125	18.047	EPSD	COSMIC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	Q8WZ42	TTN	P17252	PRKCA	S4987	P4983L	4983	Missense	distal	-4	no	18.125	17.865	EPSD	COSMIC;GDSC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	Q8WZ42	TTN	P17252	PRKCA	S4987	P4983S	4983	Missense	distal	-4	no	18.125	18.296	EPSD	COSMIC	16.704	Up-regulation
AGC_PKC_PKCa_PRKCA_ST	Q8WZ42	TTN	P17252	PRKCA	S4987	P4983Q	4983	Missense	distal	-4	no	18.125	18.113	EPSD	COSMIC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	Q8WZ42	TTN	P17252	PRKCA	S4993	A4999E	4999	Missense	distal	6	no	21.337	21.272	EPSD	COSMIC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	Q8WZ42	TTN	P17252	PRKCA	S4993	K4988I	4988	Missense	distal	-5	no	21.337	20.778	EPSD	COSMIC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	Q8WZ42	TTN	P17252	PRKCA	S4993	V4998A	4998	Missense	distal	5	no	21.337	21.721	EPSD	COSMIC	16.704	Up-regulation
AGC_PKC_PKCa_PRKCA_ST	Q8WZ42	TTN	P17252	PRKCA	S4993	Q5000R	5000	Missense	distal	7	no	21.337	21.341	EPSD	COSMIC	16.704	Up-regulation
AGC_PKC_PKCa_PRKCA_ST	Q8WZ42	TTN	P17252	PRKCA	S4993	S4993G	4993	Missense	central	0	yes	21.337	0.000	EPSD	COSMIC	16.704	Loss
AGC_PKC_PKCa_PRKCA_ST	Q8WZ42	TTN	P17252	PRKCA	S5072	P5068T	5068	Missense	distal	-4	no	17.105	16.615	EPSD	COSMIC	16.704	Loss
AGC_PKC_PKCa_PRKCA_ST	Q8WZ42	TTN	P17252	PRKCA	S5072	K5075Q	5075	Missense	distal	3	no	17.105	15.274	EPSD	COSMIC	16.704	Loss
AGC_PKC_PKCa_PRKCA_ST	Q8WZ42	TTN	P17252	PRKCA	S5083	D5084N	5084	Missense	proximal	1	no	16.596	17.069	EPSD	COSMIC	16.704	Gain
AGC_PKC_PKCa_PRKCA_ST	Q8WZ42	TTN	P17252	PRKCA	S5270	K5272E	5272	Missense	proximal	2	no	18.889	13.609	EPSD	COSMIC	16.704	Loss
AGC_PKC_PKCa_PRKCA_ST	Q8WZ42	TTN	P17252	PRKCA	S5270	S5276F	5276	Missense	distal	6	no	18.889	18.847	EPSD	COSMIC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	Q8WZ42	TTN	P17252	PRKCA	S5270	M5275I	5275	Missense	distal	5	no	18.889	18.568	EPSD	COSMIC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	Q8WZ42	TTN	P17252	PRKCA	S5276	A5282S	5282	Missense	distal	6	no	20.337	20.307	EPSD	COSMIC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	Q8WZ42	TTN	P17252	PRKCA	S5276	K5272E	5272	Missense	distal	-4	no	20.337	19.606	EPSD	COSMIC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	Q8WZ42	TTN	P17252	PRKCA	S5276	A5282T	5282	Missense	distal	6	no	20.337	20.259	EPSD	COSMIC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	Q8WZ42	TTN	P17252	PRKCA	S5276	S5276F	5276	Missense	central	0	yes	20.337	0.000	EPSD	COSMIC	16.704	Loss
AGC_PKC_PKCa_PRKCA_ST	Q8WZ42	TTN	P17252	PRKCA	S5276	M5275I	5275	Missense	proximal	-1	no	20.337	18.394	EPSD	COSMIC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	Q8WZ42	TTN	P17252	PRKCA	S5276	S5280G	5280	Missense	distal	4	no	20.337	19.979	EPSD	COSMIC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	Q8WZ42	TTN	P17252	PRKCA	S5404	R5410C	5410	Missense	distal	6	no	18.159	17.920	EPSD	COSMIC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	Q8WZ42	TTN	P17252	PRKCA	S5404	R5410K	5410	Missense	distal	6	no	18.159	18.146	EPSD	COSMIC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	Q8WZ42	TTN	P17252	PRKCA	S5404	R5406G	5406	Missense	proximal	2	no	18.159	12.913	EPSD	COSMIC	16.704	Loss
AGC_PKC_PKCa_PRKCA_ST	Q8WZ42	TTN	P17252	PRKCA	S5404	R5406T	5406	Missense	proximal	2	no	18.159	13.348	EPSD	COSMIC	16.704	Loss
AGC_PKC_PKCa_PRKCA_ST	Q8WZ42	TTN	P17252	PRKCA	S5424	S5421F	5421	Missense	distal	-3	no	17.362	17.611	EPSD	COSMIC	16.704	Up-regulation
AGC_PKC_PKCa_PRKCA_ST	Q8WZ42	TTN	P17252	PRKCA	S5424	L5425F	5425	Missense	proximal	1	no	17.362	18.020	EPSD	COSMIC	16.704	Up-regulation
AGC_PKC_PKCa_PRKCA_ST	Q8WZ42	TTN	P17252	PRKCA	S5424	A5431T	5431	Missense	distal	7	no	17.362	17.371	EPSD	COSMIC	16.704	Up-regulation
AGC_PKC_PKCa_PRKCA_ST	Q8WZ42	TTN	P17252	PRKCA	S5501	E5504K	5504	Missense	distal	3	no	17.285	17.901	EPSD	COSMIC	16.704	Up-regulation
AGC_PKC_PKCa_PRKCA_ST	Q8WZ42	TTN	P17252	PRKCA	S5501	V5502I	5502	Missense	proximal	1	no	17.285	17.996	EPSD	COSMIC	16.704	Up-regulation
AGC_PKC_PKCa_PRKCA_ST	Q8WZ42	TTN	P17252	PRKCA	S5588	R5586Q	5586	Missense	proximal	-2	no	18.546	16.787	EPSD	COSMIC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	Q8WZ42	TTN	P17252	PRKCA	S5588	G5585S	5585	Missense	distal	-3	no	18.546	18.938	EPSD	COSMIC	16.704	Up-regulation
AGC_PKC_PKCa_PRKCA_ST	Q8WZ42	TTN	P17252	PRKCA	S5588	D5583V	5583	Missense	distal	-5	no	18.546	18.367	EPSD	COSMIC;GDSC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	Q8WZ42	TTN	P17252	PRKCA	S5603	I5600K	5600	Missense	distal	-3	no	14.756	17.217	EPSD	COSMIC	16.704	Gain
AGC_PKC_PKCa_PRKCA_ST	Q8WZ42	TTN	P17252	PRKCA	T5690	H5688Y	5688	Missense	proximal	-2	no	16.130	17.956	EPSD	COSMIC	16.704	Gain
AGC_PKC_PKCa_PRKCA_ST	Q8WZ42	TTN	P17252	PRKCA	T5690	H5688N	5688	Missense	proximal	-2	no	16.130	17.488	EPSD	COSMIC	16.704	Gain
AGC_PKC_PKCa_PRKCA_ST	Q8WZ42	TTN	P17252	PRKCA	T5690	G5687R	5687	Missense	distal	-3	no	16.130	19.392	EPSD	COSMIC	16.704	Gain
AGC_PKC_PKCa_PRKCA_ST	Q8WZ42	TTN	P17252	PRKCA	S6124	R6126I	6126	Missense	proximal	2	no	16.762	11.730	EPSD	COSMIC	16.704	Loss
AGC_PKC_PKCa_PRKCA_ST	Q8WZ42	TTN	P17252	PRKCA	S6124	R6126M	6126	Missense	proximal	2	no	16.762	12.314	EPSD	COSMIC	16.704	Loss
AGC_PKC_PKCa_PRKCA_ST	Q8WZ42	TTN	P17252	PRKCA	S6124	R6126S	6126	Missense	proximal	2	no	16.762	12.142	EPSD	COSMIC	16.704	Loss
AGC_PKC_PKCa_PRKCA_ST	Q8WZ42	TTN	P17252	PRKCA	S6135	D6134N	6134	Missense	proximal	-1	no	16.694	17.032	EPSD	COSMIC	16.704	Gain
AGC_PKC_PKCa_PRKCA_ST	Q8WZ42	TTN	P17252	PRKCA	S6545	V6548G	6548	Missense	distal	3	no	15.863	17.078	EPSD	COSMIC	16.704	Gain
AGC_PKC_PKCa_PRKCA_ST	Q8WZ42	TTN	P17252	PRKCA	S6680	Q6675H	6675	Missense	distal	-5	no	17.646	17.442	EPSD	COSMIC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	Q8WZ42	TTN	P17252	PRKCA	S6680	F6679L	6679	Missense	proximal	-1	no	17.646	17.934	EPSD	COSMIC;GDSC	16.704	Up-regulation
AGC_PKC_PKCa_PRKCA_ST	Q8WZ42	TTN	P17252	PRKCA	S6680	N6683Y	6683	Missense	distal	3	no	17.646	16.948	EPSD	COSMIC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	Q8WZ42	TTN	P17252	PRKCA	S6687	L6691V	6691	Missense	distal	4	no	17.125	16.596	EPSD	COSMIC	16.704	Loss
AGC_PKC_PKCa_PRKCA_ST	Q8WZ42	TTN	P17252	PRKCA	S6687	R6689G	6689	Missense	proximal	2	no	17.125	11.880	EPSD	COSMIC	16.704	Loss
AGC_PKC_PKCa_PRKCA_ST	Q8WZ42	TTN	P17252	PRKCA	S6687	N6683Y	6683	Missense	distal	-4	no	17.125	17.262	EPSD	COSMIC	16.704	Up-regulation
AGC_PKC_PKCa_PRKCA_ST	Q8WZ42	TTN	P17252	PRKCA	S7088	S7083F	7083	Missense	distal	-5	no	16.676	16.779	EPSD	COSMIC	16.704	Gain
AGC_PKC_PKCa_PRKCA_ST	Q8WZ42	TTN	P17252	PRKCA	S7088	T7091N	7091	Missense	distal	3	no	16.676	16.943	EPSD	COSMIC	16.704	Gain
AGC_PKC_PKCa_PRKCA_ST	Q8WZ42	TTN	P17252	PRKCA	S7088	V7092M	7092	Missense	distal	4	no	16.676	18.048	EPSD	COSMIC	16.704	Gain
AGC_PKC_PKCa_PRKCA_ST	Q8WZ42	TTN	P17252	PRKCA	S7308	G7306R	7306	Missense	proximal	-2	no	15.897	18.769	EPSD	COSMIC	16.704	Gain
AGC_PKC_PKCa_PRKCA_ST	Q8WZ42	TTN	P17252	PRKCA	S7330	D7329H	7329	Missense	proximal	-1	no	16.585	17.145	EPSD	COSMIC	16.704	Gain
AGC_PKC_PKCa_PRKCA_ST	Q8WZ42	TTN	P17252	PRKCA	S7471	E7476V	7476	Missense	distal	5	no	17.534	17.382	EPSD	COSMIC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	Q8WZ42	TTN	P17252	PRKCA	S7471	D7466G	7466	Missense	distal	-5	no	17.534	17.629	EPSD	COSMIC	16.704	Up-regulation
AGC_PKC_PKCa_PRKCA_ST	Q8WZ42	TTN	P17252	PRKCA	S7471	P7478S	7478	Missense	distal	7	no	17.534	17.498	EPSD	COSMIC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	Q8WZ42	TTN	P17252	PRKCA	S7613	E7611Q	7611	Missense	proximal	-2	no	15.539	17.906	EPSD	COSMIC	16.704	Gain
AGC_PKC_PKCa_PRKCA_ST	Q8WZ42	TTN	P17252	PRKCA	S7628	A7634T	7634	Missense	distal	6	no	17.767	17.689	EPSD	COSMIC;CCLE	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	Q8WZ42	TTN	P17252	PRKCA	S7628	V7626M	7626	Missense	proximal	-2	no	17.767	18.628	EPSD	COSMIC	16.704	Up-regulation
AGC_PKC_PKCa_PRKCA_ST	Q8WZ42	TTN	P17252	PRKCA	S8276	S8277I	8277	Missense	proximal	1	no	18.369	20.031	EPSD	COSMIC	16.704	Up-regulation
AGC_PKC_PKCa_PRKCA_ST	Q8WZ42	TTN	P17252	PRKCA	S8276	F8279L	8279	Missense	distal	3	no	18.369	18.035	EPSD	COSMIC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	Q8WZ42	TTN	P17252	PRKCA	S8276	M8281L	8281	Missense	distal	5	no	18.369	18.051	EPSD	COSMIC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	Q8WZ42	TTN	P17252	PRKCA	S8276	K8278E	8278	Missense	proximal	2	no	18.369	13.090	EPSD	COSMIC	16.704	Loss
AGC_PKC_PKCa_PRKCA_ST	Q8WZ42	TTN	P17252	PRKCA	S8543	W8546R	8546	Missense	distal	3	no	15.196	18.130	EPSD	COSMIC	16.704	Gain
AGC_PKC_PKCa_PRKCA_ST	Q8WZ42	TTN	P17252	PRKCA	T8544	W8546R	8546	Missense	proximal	2	no	11.568	17.008	EPSD	COSMIC	16.704	Gain
AGC_PKC_PKCa_PRKCA_ST	Q8WZ42	TTN	P17252	PRKCA	S9193	E9190K	9190	Missense	distal	-3	no	15.379	18.291	EPSD	COSMIC	16.704	Gain
AGC_PKC_PKCa_PRKCA_ST	Q8WZ42	TTN	P17252	PRKCA	S9559	D9562G	9562	Missense	distal	3	no	16.636	17.721	EPSD	COSMIC	16.704	Gain
AGC_PKC_PKCa_PRKCA_ST	Q8WZ42	TTN	P17252	PRKCA	S9559	E9555K	9555	Missense	distal	-4	no	16.636	17.367	EPSD	COSMIC	16.704	Gain
AGC_PKC_PKCa_PRKCA_ST	Q8WZ42	TTN	P17252	PRKCA	S9559	E9563A	9563	Missense	distal	4	no	16.636	16.774	EPSD	COSMIC	16.704	Gain
AGC_PKC_PKCa_PRKCA_ST	Q8WZ42	TTN	P17252	PRKCA	S9578	T9580I	9580	Missense	proximal	2	no	16.839	16.617	EPSD	COSMIC	16.704	Loss
AGC_PKC_PKCa_PRKCA_ST	Q8WZ42	TTN	P17252	PRKCA	S9578	V9583D	9583	Missense	distal	5	no	16.839	16.899	EPSD	COSMIC	16.704	Up-regulation
AGC_PKC_PKCa_PRKCA_ST	Q8WZ42	TTN	P17252	PRKCA	S9578	R9576I	9576	Missense	proximal	-2	no	16.839	13.251	EPSD	COSMIC	16.704	Loss
AGC_PKC_PKCa_PRKCA_ST	Q8WZ42	TTN	P17252	PRKCA	S9578	L9577Q	9577	Missense	proximal	-1	no	16.839	16.828	EPSD	COSMIC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	Q8WZ42	TTN	P17252	PRKCA	S9633	E9631K	9631	Missense	proximal	-2	no	14.429	16.927	EPSD	COSMIC	16.704	Gain
AGC_PKC_PKCa_PRKCA_ST	Q8WZ42	TTN	P17252	PRKCA	T9970	T9970R	9970	Missense	central	0	yes	17.131	0.000	EPSD	COSMIC	16.704	Loss
AGC_PKC_PKCa_PRKCA_ST	Q8WZ42	TTN	P17252	PRKCA	T9970	Q9976R	9976	Missense	distal	6	no	17.131	17.254	EPSD	COSMIC;CCLE	16.704	Up-regulation
AGC_PKC_PKCa_PRKCA_ST	Q8WZ42	TTN	P17252	PRKCA	T9970	E9974K	9974	Missense	distal	4	no	17.131	17.670	EPSD	COSMIC	16.704	Up-regulation
AGC_PKC_PKCa_PRKCA_ST	Q8WZ42	TTN	P17252	PRKCA	T9970	T9970P	9970	Missense	central	0	yes	17.131	0.000	EPSD	COSMIC	16.704	Loss
AGC_PKC_PKCa_PRKCA_ST	Q8WZ42	TTN	P17252	PRKCA	T9970	T9968I	9968	Missense	proximal	-2	no	17.131	16.437	EPSD	COSMIC	16.704	Loss
AGC_PKC_PKCa_PRKCA_ST	Q8WZ42	TTN	P17252	PRKCA	T9970	K9972E	9972	Missense	proximal	2	no	17.131	11.851	EPSD	COSMIC	16.704	Loss
AGC_PKC_PKCa_PRKCA_ST	Q8WZ42	TTN	P17252	PRKCA	T9970	E9963D	9963	Missense	distal	-7	no	17.131	17.134	EPSD	COSMIC;CCLE	16.704	Up-regulation
AGC_PKC_PKCa_PRKCA_ST	Q8WZ42	TTN	P17252	PRKCA	S10781	R10785H	10785	Missense	distal	4	no	17.301	17.019	EPSD	COSMIC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	Q8WZ42	TTN	P17252	PRKCA	S10781	R10779H	10779	Missense	proximal	-2	no	17.301	12.748	EPSD	COSMIC	16.704	Loss
AGC_PKC_PKCa_PRKCA_ST	Q8WZ42	TTN	P17252	PRKCA	S10781	K10787N	10787	Missense	distal	6	no	17.301	17.140	EPSD	COSMIC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	Q8WZ42	TTN	P17252	PRKCA	S10781	E10786D	10786	Missense	distal	5	no	17.301	17.209	EPSD	COSMIC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	Q8WZ42	TTN	P17252	PRKCA	S11878	R11883K	11883	Missense	distal	5	no	16.629	16.773	EPSD;PhosphoSitePlus	COSMIC	16.704	Gain
AGC_PKC_PKCa_PRKCA_ST	Q8WZ42	TTN	P17252	PRKCA	S11878	E11873K	11873	Missense	distal	-5	no	16.629	16.924	EPSD;PhosphoSitePlus	COSMIC	16.704	Gain
AGC_PKC_PKCa_PRKCA_ST	Q8WZ42	TTN	P17252	PRKCA	S11878	E11885K	11885	Missense	distal	7	no	16.629	16.775	EPSD;PhosphoSitePlus	COSMIC	16.704	Gain
AGC_PKC_PKCa_PRKCA_ST	Q8WZ42	TTN	P17252	PRKCA	S11878	V11879F	11879	Missense	proximal	1	no	16.629	17.162	EPSD;PhosphoSitePlus	COSMIC	16.704	Gain
AGC_PKC_PKCa_PRKCA_ST	Q8WZ42	TTN	P17252	PRKCA	S12022	P12027S	12027	Missense	distal	5	no	17.554	17.395	PhosphoSitePlus;EPSD	COSMIC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	Q8WZ42	TTN	P17252	PRKCA	S12022	P12020S	12020	Missense	proximal	-2	no	17.554	17.295	PhosphoSitePlus;EPSD	COSMIC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	Q8WZ42	TTN	P17252	PRKCA	S12022	P12028S	12028	Missense	distal	6	no	17.554	17.521	PhosphoSitePlus;EPSD	COSMIC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	Q8WZ42	TTN	P17252	PRKCA	S12022	R12015K	12015	Missense	distal	-7	no	17.554	17.549	PhosphoSitePlus;EPSD	COSMIC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	Q8WZ42	TTN	P17252	PRKCA	S12022	K12017N	12017	Missense	distal	-5	no	17.554	17.211	PhosphoSitePlus;EPSD	COSMIC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	Q8WZ42	TTN	P17252	PRKCA	S12022	G12021A	12021	Missense	proximal	-1	no	17.554	16.747	PhosphoSitePlus;EPSD	COSMIC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	Q8WZ42	TTN	P17252	PRKCA	S12088	P12089H	12089	Missense	proximal	1	no	22.860	22.821	EPSD	COSMIC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	Q8WZ42	TTN	P17252	PRKCA	S12088	E12087D	12087	Missense	proximal	-1	no	22.860	22.346	EPSD	COSMIC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	Q8WZ42	TTN	P17252	PRKCA	S12088	R12086H	12086	Missense	proximal	-2	no	22.860	18.307	EPSD	COSMIC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	Q8WZ42	TTN	P17252	PRKCA	S12088	R12086S	12086	Missense	proximal	-2	no	22.860	19.558	EPSD	COSMIC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	Q8WZ42	TTN	P17252	PRKCA	S12491	K12488R	12488	Missense	distal	-3	no	19.668	21.694	EPSD	COSMIC	16.704	Up-regulation
AGC_PKC_PKCa_PRKCA_ST	Q8WZ42	TTN	P17252	PRKCA	S12491	G12487V	12487	Missense	distal	-4	no	19.668	19.104	EPSD	COSMIC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	Q8WZ42	TTN	P17252	PRKCA	S12505	F12503L	12503	Missense	proximal	-2	no	15.513	16.798	EPSD	COSMIC	16.704	Gain
AGC_PKC_PKCa_PRKCA_ST	Q8WZ42	TTN	P17252	PRKCA	S12525	E12527K	12527	Missense	proximal	2	no	12.074	17.354	EPSD	COSMIC	16.704	Gain
AGC_PKC_PKCa_PRKCA_ST	Q8WZ42	TTN	P17252	PRKCA	S12635	G12640D	12640	Missense	distal	5	no	18.921	18.840	EPSD	COSMIC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	Q8WZ42	TTN	P17252	PRKCA	S12635	P12632L	12632	Missense	distal	-3	no	18.921	18.414	EPSD	COSMIC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	Q8WZ42	TTN	P17252	PRKCA	T12866	P12861L	12861	Missense	distal	-5	no	16.705	16.678	EPSD	COSMIC	16.704	Loss
AGC_PKC_PKCa_PRKCA_ST	Q8WZ42	TTN	P17252	PRKCA	S12911	S12918F	12918	Missense	distal	7	no	18.194	18.131	EPSD	COSMIC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	Q8WZ42	TTN	P17252	PRKCA	S12911	T12909N	12909	Missense	proximal	-2	no	18.194	17.892	EPSD	COSMIC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	Q8WZ42	TTN	P17252	PRKCA	S12911	S12911W	12911	Missense	central	0	yes	18.194	0.000	EPSD	COSMIC	16.704	Loss
AGC_PKC_PKCa_PRKCA_ST	Q8WZ42	TTN	P17252	PRKCA	T13180	H13177R	13177	Missense	distal	-3	no	14.791	18.647	EPSD	COSMIC	16.704	Gain
AGC_PKC_PKCa_PRKCA_ST	Q8WZ42	TTN	P17252	PRKCA	S13707	V13700I	13700	Missense	distal	-7	no	19.302	19.301	EPSD	COSMIC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	Q8WZ42	TTN	P17252	PRKCA	S13707	Y13713C	13713	Missense	distal	6	no	19.302	19.115	EPSD	COSMIC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	Q8WZ42	TTN	P17252	PRKCA	S13707	R13709S	13709	Missense	proximal	2	no	19.302	14.682	EPSD	COSMIC;CCLE	16.704	Loss
AGC_PKC_PKCa_PRKCA_ST	Q8WZ42	TTN	P17252	PRKCA	S13707	R13709I	13709	Missense	proximal	2	no	19.302	14.270	EPSD	COSMIC;CCLE	16.704	Loss
AGC_PKC_PKCa_PRKCA_ST	Q8WZ42	TTN	P17252	PRKCA	S13980	K13987T	13987	Missense	distal	7	no	17.668	17.578	EPSD	COSMIC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	Q8WZ42	TTN	P17252	PRKCA	S13980	D13973N	13973	Missense	distal	-7	no	17.668	17.667	EPSD	COSMIC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	Q8WZ42	TTN	P17252	PRKCA	S14387	S14382F	14382	Missense	distal	-5	no	17.851	17.954	EPSD	COSMIC	16.704	Up-regulation
AGC_PKC_PKCa_PRKCA_ST	Q8WZ42	TTN	P17252	PRKCA	S14387	R14386H	14386	Missense	proximal	-1	no	17.851	17.528	EPSD	COSMIC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	Q8WZ42	TTN	P17252	PRKCA	S14387	P14383T	14383	Missense	distal	-4	no	17.851	17.361	EPSD	COSMIC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	Q8WZ42	TTN	P17252	PRKCA	T14402	R14399C	14399	Missense	distal	-3	no	17.086	14.347	EPSD	COSMIC	16.704	Loss
AGC_PKC_PKCa_PRKCA_ST	Q8WZ42	TTN	P17252	PRKCA	T14402	R14399H	14399	Missense	distal	-3	no	17.086	13.230	EPSD	COSMIC	16.704	Loss
AGC_PKC_PKCa_PRKCA_ST	Q8WZ42	TTN	P17252	PRKCA	T14402	D14408N	14408	Missense	distal	6	no	17.086	17.002	EPSD	COSMIC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	Q8WZ42	TTN	P17252	PRKCA	T14402	I14403M	14403	Missense	proximal	1	no	17.086	16.035	EPSD	COSMIC	16.704	Loss
AGC_PKC_PKCa_PRKCA_ST	Q8WZ42	TTN	P17252	PRKCA	T14402	R14399S	14399	Missense	distal	-3	no	17.086	14.216	EPSD	COSMIC	16.704	Loss
AGC_PKC_PKCa_PRKCA_ST	Q8WZ42	TTN	P17252	PRKCA	S14457	E14455K	14455	Missense	proximal	-2	no	17.800	20.298	EPSD	COSMIC	16.704	Up-regulation
AGC_PKC_PKCa_PRKCA_ST	Q8WZ42	TTN	P17252	PRKCA	S14457	R14458W	14458	Missense	proximal	1	no	17.800	17.076	EPSD	COSMIC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	Q8WZ42	TTN	P17252	PRKCA	S14457	S14457I	14457	Missense	central	0	yes	17.800	0.000	EPSD	COSMIC	16.704	Loss
AGC_PKC_PKCa_PRKCA_ST	Q8WZ42	TTN	P17252	PRKCA	S14680	T14676A	14676	Missense	distal	-4	no	17.367	18.115	EPSD	COSMIC	16.704	Up-regulation
AGC_PKC_PKCa_PRKCA_ST	Q8WZ42	TTN	P17252	PRKCA	S14680	S14673F	14673	Missense	distal	-7	no	17.367	17.359	EPSD	COSMIC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	Q8WZ42	TTN	P17252	PRKCA	S14680	I14677T	14677	Missense	distal	-3	no	17.367	17.691	EPSD	COSMIC	16.704	Up-regulation
AGC_PKC_PKCa_PRKCA_ST	Q8WZ42	TTN	P17252	PRKCA	S14680	R14682I	14682	Missense	proximal	2	no	17.367	12.335	EPSD	COSMIC	16.704	Loss
AGC_PKC_PKCa_PRKCA_ST	Q8WZ42	TTN	P17252	PRKCA	T14868	V14864A	14864	Missense	distal	-4	no	16.744	17.303	EPSD	COSMIC	16.704	Up-regulation
AGC_PKC_PKCa_PRKCA_ST	Q8WZ42	TTN	P17252	PRKCA	T14868	K14865Q	14865	Missense	distal	-3	no	16.744	15.912	EPSD	COSMIC;CCLE	16.704	Loss
AGC_PKC_PKCa_PRKCA_ST	Q8WZ42	TTN	P17252	PRKCA	T14868	T14875I	14875	Missense	distal	7	no	16.744	16.584	EPSD	COSMIC	16.704	Loss
AGC_PKC_PKCa_PRKCA_ST	Q8WZ42	TTN	P17252	PRKCA	T14875	N14876S	14876	Missense	proximal	1	no	19.545	19.498	EPSD	COSMIC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	Q8WZ42	TTN	P17252	PRKCA	T14875	T14875I	14875	Missense	central	0	yes	19.545	0.000	EPSD	COSMIC	16.704	Loss
AGC_PKC_PKCa_PRKCA_ST	Q8WZ42	TTN	P17252	PRKCA	S14926	R14928Q	14928	Missense	proximal	2	no	17.840	14.005	EPSD	COSMIC	16.704	Loss
AGC_PKC_PKCa_PRKCA_ST	Q8WZ42	TTN	P17252	PRKCA	S14926	K14920E	14920	Missense	distal	-6	no	17.840	17.772	EPSD	COSMIC;CCLE	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	Q8WZ42	TTN	P17252	PRKCA	S14926	K14933I	14933	Missense	distal	7	no	17.840	17.590	EPSD	COSMIC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	Q8WZ42	TTN	P17252	PRKCA	S14926	G14923R	14923	Missense	distal	-3	no	17.840	21.101	EPSD	COSMIC	16.704	Up-regulation
AGC_PKC_PKCa_PRKCA_ST	Q8WZ42	TTN	P17252	PRKCA	S15263	N15262D	15262	Missense	proximal	-1	no	18.264	17.926	EPSD	COSMIC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	Q8WZ42	TTN	P17252	PRKCA	S15263	P15265T	15265	Missense	proximal	2	no	18.264	18.656	EPSD	COSMIC	16.704	Up-regulation
AGC_PKC_PKCa_PRKCA_ST	Q8WZ42	TTN	P17252	PRKCA	S15263	R15264H	15264	Missense	proximal	1	no	18.264	17.451	EPSD	COSMIC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	Q8WZ42	TTN	P17252	PRKCA	S15682	D15684G	15684	Missense	proximal	2	no	17.184	17.217	EPSD	COSMIC	16.704	Up-regulation
AGC_PKC_PKCa_PRKCA_ST	Q8WZ42	TTN	P17252	PRKCA	S15682	R15680C	15680	Missense	proximal	-2	no	17.184	15.484	EPSD	COSMIC;CCLE	16.704	Loss
AGC_PKC_PKCa_PRKCA_ST	Q8WZ42	TTN	P17252	PRKCA	S15682	K15687T	15687	Missense	distal	5	no	17.184	16.723	EPSD	COSMIC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	Q8WZ42	TTN	P17252	PRKCA	S15682	G15689A	15689	Missense	distal	7	no	17.184	17.160	EPSD	COSMIC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	Q8WZ42	TTN	P17252	PRKCA	S15686	L15693I	15693	Missense	distal	7	no	19.282	19.126	EPSD	COSMIC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	Q8WZ42	TTN	P17252	PRKCA	S15686	D15684G	15684	Missense	proximal	-2	no	19.282	19.828	EPSD	COSMIC	16.704	Up-regulation
AGC_PKC_PKCa_PRKCA_ST	Q8WZ42	TTN	P17252	PRKCA	S15686	R15680C	15680	Missense	distal	-6	no	19.282	18.913	EPSD	COSMIC;CCLE	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	Q8WZ42	TTN	P17252	PRKCA	S15686	K15687T	15687	Missense	proximal	1	no	19.282	18.398	EPSD	COSMIC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	Q8WZ42	TTN	P17252	PRKCA	S15686	G15689A	15689	Missense	distal	3	no	19.282	18.324	EPSD	COSMIC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	Q8WZ42	TTN	P17252	PRKCA	S15691	L15693I	15693	Missense	proximal	2	no	16.883	16.838	EPSD	COSMIC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	Q8WZ42	TTN	P17252	PRKCA	S15691	R15694L	15694	Missense	distal	3	no	16.883	14.645	EPSD	COSMIC	16.704	Loss
AGC_PKC_PKCa_PRKCA_ST	Q8WZ42	TTN	P17252	PRKCA	S15691	R15696Q	15696	Missense	distal	5	no	16.883	16.875	EPSD	COSMIC;CCLE	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	Q8WZ42	TTN	P17252	PRKCA	S15691	K15687T	15687	Missense	distal	-4	no	16.883	15.993	EPSD	COSMIC	16.704	Loss
AGC_PKC_PKCa_PRKCA_ST	Q8WZ42	TTN	P17252	PRKCA	S15691	G15689A	15689	Missense	proximal	-2	no	16.883	16.670	EPSD	COSMIC	16.704	Loss
AGC_PKC_PKCa_PRKCA_ST	Q8WZ42	TTN	P17252	PRKCA	S15744	P15751S	15751	Missense	distal	7	no	16.939	16.903	EPSD	COSMIC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	Q8WZ42	TTN	P17252	PRKCA	S15744	F15737I	15737	Missense	distal	-7	no	16.939	16.937	EPSD	COSMIC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	Q8WZ42	TTN	P17252	PRKCA	S15744	E15750K	15750	Missense	distal	6	no	16.939	17.033	EPSD	COSMIC	16.704	Up-regulation
AGC_PKC_PKCa_PRKCA_ST	Q8WZ42	TTN	P17252	PRKCA	T15989	E15995D	15995	Missense	distal	6	no	19.994	20.011	EPSD	COSMIC	16.704	Up-regulation
AGC_PKC_PKCa_PRKCA_ST	Q8WZ42	TTN	P17252	PRKCA	T15989	E15992K	15992	Missense	distal	3	no	19.994	20.610	EPSD	COSMIC	16.704	Up-regulation
AGC_PKC_PKCa_PRKCA_ST	Q8WZ42	TTN	P17252	PRKCA	T15989	T15989N	15989	Missense	central	0	yes	19.994	0.000	EPSD	COSMIC	16.704	Loss
AGC_PKC_PKCa_PRKCA_ST	Q8WZ42	TTN	P17252	PRKCA	T15989	R15986Q	15986	Missense	distal	-3	no	19.994	17.136	EPSD	COSMIC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	Q8WZ42	TTN	P17252	PRKCA	S16111	A16116V	16116	Missense	distal	5	no	16.986	16.602	EPSD	COSMIC	16.704	Loss
AGC_PKC_PKCa_PRKCA_ST	Q8WZ42	TTN	P17252	PRKCA	S16111	A16116S	16116	Missense	distal	5	no	16.986	16.883	EPSD	COSMIC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	Q8WZ42	TTN	P17252	PRKCA	S16111	C16109F	16109	Missense	proximal	-2	no	16.986	14.713	EPSD	COSMIC	16.704	Loss
AGC_PKC_PKCa_PRKCA_ST	Q8WZ42	TTN	P17252	PRKCA	S16111	S16111Y	16111	Missense	central	0	yes	16.986	0.000	EPSD	COSMIC	16.704	Loss
AGC_PKC_PKCa_PRKCA_ST	Q8WZ42	TTN	P17252	PRKCA	S16111	A16115V	16115	Missense	distal	4	no	16.986	15.648	EPSD	COSMIC	16.704	Loss
AGC_PKC_PKCa_PRKCA_ST	Q8WZ42	TTN	P17252	PRKCA	S16111	C16109S	16109	Missense	proximal	-2	no	16.986	15.384	EPSD	COSMIC	16.704	Loss
AGC_PKC_PKCa_PRKCA_ST	Q8WZ42	TTN	P17252	PRKCA	S16111	N16107K	16107	Missense	distal	-4	no	16.986	17.545	EPSD	COSMIC	16.704	Up-regulation
AGC_PKC_PKCa_PRKCA_ST	Q8WZ42	TTN	P17252	PRKCA	S16236	L16240P	16240	Missense	distal	4	no	16.210	16.803	EPSD	COSMIC	16.704	Gain
AGC_PKC_PKCa_PRKCA_ST	Q8WZ42	TTN	P17252	PRKCA	S16329	I16335V	16335	Missense	distal	6	no	20.986	20.931	EPSD	COSMIC;CCLE	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	Q8WZ42	TTN	P17252	PRKCA	S16329	T16323A	16323	Missense	distal	-6	no	20.986	21.074	EPSD	COSMIC	16.704	Up-regulation
AGC_PKC_PKCa_PRKCA_ST	Q8WZ42	TTN	P17252	PRKCA	S16329	K16325M	16325	Missense	distal	-4	no	20.986	21.029	EPSD	COSMIC	16.704	Up-regulation
AGC_PKC_PKCa_PRKCA_ST	Q8WZ42	TTN	P17252	PRKCA	S16329	D16333Y	16333	Missense	distal	4	no	20.986	20.941	EPSD	COSMIC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	Q8WZ42	TTN	P17252	PRKCA	S16329	R16331I	16331	Missense	proximal	2	no	20.986	15.954	EPSD	COSMIC	16.704	Loss
AGC_PKC_PKCa_PRKCA_ST	Q8WZ42	TTN	P17252	PRKCA	S16329	T16334I	16334	Missense	distal	5	no	20.986	20.967	EPSD	COSMIC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	Q8WZ42	TTN	P17252	PRKCA	T16334	V16337G	16337	Missense	distal	3	no	18.620	19.834	EPSD	COSMIC	16.704	Up-regulation
AGC_PKC_PKCa_PRKCA_ST	Q8WZ42	TTN	P17252	PRKCA	T16334	I16335V	16335	Missense	proximal	1	no	18.620	17.909	EPSD	COSMIC;CCLE	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	Q8WZ42	TTN	P17252	PRKCA	T16334	D16333Y	16333	Missense	proximal	-1	no	18.620	18.666	EPSD	COSMIC	16.704	Up-regulation
AGC_PKC_PKCa_PRKCA_ST	Q8WZ42	TTN	P17252	PRKCA	T16334	R16331I	16331	Missense	distal	-3	no	18.620	14.133	EPSD	COSMIC	16.704	Loss
AGC_PKC_PKCa_PRKCA_ST	Q8WZ42	TTN	P17252	PRKCA	T16334	T16334I	16334	Missense	central	0	yes	18.620	0.000	EPSD	COSMIC	16.704	Loss
AGC_PKC_PKCa_PRKCA_ST	Q8WZ42	TTN	P17252	PRKCA	S16412	R16409C	16409	Missense	distal	-3	no	18.070	15.331	EPSD	COSMIC	16.704	Loss
AGC_PKC_PKCa_PRKCA_ST	Q8WZ42	TTN	P17252	PRKCA	S16412	L16410I	16410	Missense	proximal	-2	no	18.070	17.170	EPSD	COSMIC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	Q8WZ42	TTN	P17252	PRKCA	S16412	A16406S	16406	Missense	distal	-6	no	18.070	18.107	EPSD	COSMIC	16.704	Up-regulation
AGC_PKC_PKCa_PRKCA_ST	Q8WZ42	TTN	P17252	PRKCA	S16412	V16417F	16417	Missense	distal	5	no	18.070	18.385	EPSD	COSMIC	16.704	Up-regulation
AGC_PKC_PKCa_PRKCA_ST	Q8WZ42	TTN	P17252	PRKCA	S16412	S16407F	16407	Missense	distal	-5	no	18.070	18.173	EPSD	COSMIC	16.704	Up-regulation
AGC_PKC_PKCa_PRKCA_ST	Q8WZ42	TTN	P17252	PRKCA	S16412	R16415C	16415	Missense	distal	3	no	18.070	15.452	EPSD	COSMIC	16.704	Loss
AGC_PKC_PKCa_PRKCA_ST	Q8WZ42	TTN	P17252	PRKCA	S16412	A16406V	16406	Missense	distal	-6	no	18.070	17.993	EPSD	COSMIC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	Q8WZ42	TTN	P17252	PRKCA	T16819	S16817R	16817	Missense	proximal	-2	no	15.301	18.603	EPSD	COSMIC	16.704	Gain
AGC_PKC_PKCa_PRKCA_ST	Q8WZ42	TTN	P17252	PRKCA	S16854	S16854P	16854	Missense	central	0	yes	18.253	0.000	EPSD	COSMIC	16.704	Loss
AGC_PKC_PKCa_PRKCA_ST	Q8WZ42	TTN	P17252	PRKCA	S16854	L16857F	16857	Missense	distal	3	no	18.253	18.587	EPSD	COSMIC	16.704	Up-regulation
AGC_PKC_PKCa_PRKCA_ST	Q8WZ42	TTN	P17252	PRKCA	S16854	G16853D	16853	Missense	proximal	-1	no	18.253	17.509	EPSD	COSMIC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	Q8WZ42	TTN	P17252	PRKCA	S16854	C16855F	16855	Missense	proximal	1	no	18.253	21.399	EPSD	COSMIC;CCLE	16.704	Up-regulation
AGC_PKC_PKCa_PRKCA_ST	Q8WZ42	TTN	P17252	PRKCA	S16854	K16860N	16860	Missense	distal	6	no	18.253	18.091	EPSD	COSMIC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	Q8WZ42	TTN	P17252	PRKCA	S16858	S16854P	16854	Missense	distal	-4	no	21.658	21.487	EPSD	COSMIC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	Q8WZ42	TTN	P17252	PRKCA	S16858	L16857F	16857	Missense	proximal	-1	no	21.658	21.370	EPSD	COSMIC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	Q8WZ42	TTN	P17252	PRKCA	S16858	G16853D	16853	Missense	distal	-5	no	21.658	21.563	EPSD	COSMIC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	Q8WZ42	TTN	P17252	PRKCA	S16858	C16855F	16855	Missense	distal	-3	no	21.658	21.777	EPSD	COSMIC;CCLE	16.704	Up-regulation
AGC_PKC_PKCa_PRKCA_ST	Q8WZ42	TTN	P17252	PRKCA	S16858	K16860N	16860	Missense	proximal	2	no	21.658	16.709	EPSD	COSMIC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	Q8WZ42	TTN	P17252	PRKCA	T16931	R16933T	16933	Missense	proximal	2	no	22.219	17.409	EPSD	COSMIC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	Q8WZ42	TTN	P17252	PRKCA	T16931	V16924M	16924	Missense	distal	-7	no	22.219	22.230	EPSD	COSMIC	16.704	Up-regulation
AGC_PKC_PKCa_PRKCA_ST	Q8WZ42	TTN	P17252	PRKCA	T17037	V17036M	17036	Missense	proximal	-1	no	14.748	16.870	EPSD	COSMIC	16.704	Gain
AGC_PKC_PKCa_PRKCA_ST	Q8WZ42	TTN	P17252	PRKCA	S17116	G17119C	17119	Missense	distal	3	no	19.246	17.267	EPSD	COSMIC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	Q8WZ42	TTN	P17252	PRKCA	S17116	I17110T	17110	Missense	distal	-6	no	19.246	19.217	EPSD	COSMIC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	Q8WZ42	TTN	P17252	PRKCA	S17456	R17458Q	17458	Missense	proximal	2	no	17.006	13.172	EPSD	COSMIC	16.704	Loss
AGC_PKC_PKCa_PRKCA_ST	Q8WZ42	TTN	P17252	PRKCA	S17700	T17694K	17694	Missense	distal	-6	no	17.741	17.933	EPSD	COSMIC	16.704	Up-regulation
AGC_PKC_PKCa_PRKCA_ST	Q8WZ42	TTN	P17252	PRKCA	S17700	L17698F	17698	Missense	proximal	-2	no	17.741	16.456	EPSD	COSMIC	16.704	Loss
AGC_PKC_PKCa_PRKCA_ST	Q8WZ42	TTN	P17252	PRKCA	S17700	V17705D	17705	Missense	distal	5	no	17.741	17.802	EPSD	COSMIC	16.704	Up-regulation
AGC_PKC_PKCa_PRKCA_ST	Q8WZ42	TTN	P17252	PRKCA	S17770	K17772Q	17772	Missense	proximal	2	no	18.529	15.116	EPSD	COSMIC	16.704	Loss
AGC_PKC_PKCa_PRKCA_ST	Q8WZ42	TTN	P17252	PRKCA	S17770	R17768H	17768	Missense	proximal	-2	no	18.529	13.976	EPSD	COSMIC	16.704	Loss
AGC_PKC_PKCa_PRKCA_ST	Q8WZ42	TTN	P17252	PRKCA	S17826	V17819I	17819	Missense	distal	-7	no	18.752	18.751	EPSD	COSMIC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	Q8WZ42	TTN	P17252	PRKCA	S17826	S17826Y	17826	Missense	central	0	yes	18.752	0.000	EPSD	COSMIC	16.704	Loss
AGC_PKC_PKCa_PRKCA_ST	Q8WZ42	TTN	P17252	PRKCA	S17826	G17829D	17829	Missense	distal	3	no	18.752	17.666	EPSD	COSMIC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	Q8WZ42	TTN	P17252	PRKCA	S17929	V17926L	17926	Missense	distal	-3	no	17.848	17.182	EPSD	COSMIC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	Q8WZ42	TTN	P17252	PRKCA	S17929	D17923N	17923	Missense	distal	-6	no	17.848	17.875	EPSD	COSMIC	16.704	Up-regulation
AGC_PKC_PKCa_PRKCA_ST	Q8WZ42	TTN	P17252	PRKCA	S17929	P17924T	17924	Missense	distal	-5	no	17.848	17.850	EPSD	COSMIC	16.704	Up-regulation
AGC_PKC_PKCa_PRKCA_ST	Q8WZ42	TTN	P17252	PRKCA	S17929	V17926E	17926	Missense	distal	-3	no	17.848	16.599	EPSD	COSMIC	16.704	Loss
AGC_PKC_PKCa_PRKCA_ST	Q8WZ42	TTN	P17252	PRKCA	S17981	E17978G	17978	Missense	distal	-3	no	18.580	20.256	EPSD	COSMIC	16.704	Up-regulation
AGC_PKC_PKCa_PRKCA_ST	Q8WZ42	TTN	P17252	PRKCA	S17981	S17981C	17981	Missense	central	0	yes	18.580	0.000	EPSD	COSMIC	16.704	Loss
AGC_PKC_PKCa_PRKCA_ST	Q8WZ42	TTN	P17252	PRKCA	S17981	E17978K	17978	Missense	distal	-3	no	18.580	21.492	EPSD	COSMIC	16.704	Up-regulation
AGC_PKC_PKCa_PRKCA_ST	Q8WZ42	TTN	P17252	PRKCA	S17981	R17983Q	17983	Missense	proximal	2	no	18.580	14.746	EPSD	COSMIC	16.704	Loss
AGC_PKC_PKCa_PRKCA_ST	Q8WZ42	TTN	P17252	PRKCA	S17981	S17981Y	17981	Missense	central	0	yes	18.580	0.000	EPSD	COSMIC	16.704	Loss
AGC_PKC_PKCa_PRKCA_ST	Q8WZ42	TTN	P17252	PRKCA	T18111	D18108G	18108	Missense	distal	-3	no	15.029	16.809	EPSD	COSMIC	16.704	Gain
AGC_PKC_PKCa_PRKCA_ST	Q8WZ42	TTN	P17252	PRKCA	S18583	T18577N	18577	Missense	distal	-6	no	16.676	16.745	EPSD	COSMIC	16.704	Gain
AGC_PKC_PKCa_PRKCA_ST	Q8WZ42	TTN	P17252	PRKCA	S18585	K18589N	18589	Missense	distal	4	no	17.209	16.082	EPSD	COSMIC	16.704	Loss
AGC_PKC_PKCa_PRKCA_ST	Q8WZ42	TTN	P17252	PRKCA	S18585	G18584D	18584	Missense	proximal	-1	no	17.209	16.466	EPSD	COSMIC	16.704	Loss
AGC_PKC_PKCa_PRKCA_ST	Q8WZ42	TTN	P17252	PRKCA	S19081	S19081Y	19081	Missense	central	0	yes	20.524	0.000	EPSD	COSMIC	16.704	Loss
AGC_PKC_PKCa_PRKCA_ST	Q8WZ42	TTN	P17252	PRKCA	S19081	M19088R	19088	Missense	distal	7	no	20.524	20.560	EPSD	COSMIC	16.704	Up-regulation
AGC_PKC_PKCa_PRKCA_ST	Q8WZ42	TTN	P17252	PRKCA	S19174	D19180N	19180	Missense	distal	6	no	17.207	17.123	EPSD	COSMIC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	Q8WZ42	TTN	P17252	PRKCA	S19174	P19175Q	19175	Missense	proximal	1	no	17.207	17.865	EPSD	COSMIC	16.704	Up-regulation
AGC_PKC_PKCa_PRKCA_ST	Q8WZ42	TTN	P17252	PRKCA	S19174	S19174F	19174	Missense	central	0	yes	17.207	0.000	EPSD	COSMIC	16.704	Loss
AGC_PKC_PKCa_PRKCA_ST	Q8WZ42	TTN	P17252	PRKCA	S19335	E19337K	19337	Missense	proximal	2	no	11.770	17.050	EPSD	COSMIC	16.704	Gain
AGC_PKC_PKCa_PRKCA_ST	Q8WZ42	TTN	P17252	PRKCA	S19353	Y19357C	19357	Missense	distal	4	no	16.837	16.080	EPSD	COSMIC	16.704	Loss
AGC_PKC_PKCa_PRKCA_ST	Q8WZ42	TTN	P17252	PRKCA	S19353	I19354V	19354	Missense	proximal	1	no	16.837	16.126	EPSD	COSMIC	16.704	Loss
AGC_PKC_PKCa_PRKCA_ST	Q8WZ42	TTN	P17252	PRKCA	S19353	F19358V	19358	Missense	distal	5	no	16.837	16.522	EPSD	COSMIC	16.704	Loss
AGC_PKC_PKCa_PRKCA_ST	Q8WZ42	TTN	P17252	PRKCA	S19366	W19369L	19369	Missense	distal	3	no	16.282	16.978	EPSD	COSMIC	16.704	Gain
AGC_PKC_PKCa_PRKCA_ST	Q8WZ42	TTN	P17252	PRKCA	S19763	Q19769K	19769	Missense	distal	6	no	18.953	19.063	EPSD	COSMIC	16.704	Up-regulation
AGC_PKC_PKCa_PRKCA_ST	Q8WZ42	TTN	P17252	PRKCA	S19763	E19768K	19768	Missense	distal	5	no	18.953	19.366	EPSD	COSMIC	16.704	Up-regulation
AGC_PKC_PKCa_PRKCA_ST	Q8WZ42	TTN	P17252	PRKCA	S19763	D19758N	19758	Missense	distal	-5	no	18.953	18.982	EPSD	COSMIC	16.704	Up-regulation
AGC_PKC_PKCa_PRKCA_ST	Q8WZ42	TTN	P17252	PRKCA	S19763	Y19764C	19764	Missense	proximal	1	no	18.953	16.479	EPSD	COSMIC	16.704	Loss
AGC_PKC_PKCa_PRKCA_ST	Q8WZ42	TTN	P17252	PRKCA	S19763	E19766K	19766	Missense	distal	3	no	18.953	19.568	EPSD	COSMIC	16.704	Up-regulation
AGC_PKC_PKCa_PRKCA_ST	Q8WZ42	TTN	P17252	PRKCA	T19908	G19905S	19905	Missense	distal	-3	no	16.836	17.227	EPSD	COSMIC	16.704	Up-regulation
AGC_PKC_PKCa_PRKCA_ST	Q8WZ42	TTN	P17252	PRKCA	T19908	V19913L	19913	Missense	distal	5	no	16.836	16.926	EPSD	COSMIC	16.704	Up-regulation
AGC_PKC_PKCa_PRKCA_ST	Q8WZ42	TTN	P17252	PRKCA	T19908	V19914I	19914	Missense	distal	6	no	16.836	16.890	EPSD	COSMIC	16.704	Up-regulation
AGC_PKC_PKCa_PRKCA_ST	Q8WZ42	TTN	P17252	PRKCA	T19908	V19914L	19914	Missense	distal	6	no	16.836	16.914	EPSD	COSMIC	16.704	Up-regulation
AGC_PKC_PKCa_PRKCA_ST	Q8WZ42	TTN	P17252	PRKCA	S20101	K20098R	20098	Missense	distal	-3	no	14.849	16.876	EPSD	COSMIC	16.704	Gain
AGC_PKC_PKCa_PRKCA_ST	Q8WZ42	TTN	P17252	PRKCA	T20168	V20164L	20164	Missense	distal	-4	no	17.399	17.440	EPSD	COSMIC	16.704	Up-regulation
AGC_PKC_PKCa_PRKCA_ST	Q8WZ42	TTN	P17252	PRKCA	T20168	V20164I	20164	Missense	distal	-4	no	17.399	17.429	EPSD	COSMIC	16.704	Up-regulation
AGC_PKC_PKCa_PRKCA_ST	Q8WZ42	TTN	P17252	PRKCA	T20168	A20169V	20169	Missense	proximal	1	no	17.399	17.553	EPSD	COSMIC	16.704	Up-regulation
AGC_PKC_PKCa_PRKCA_ST	Q8WZ42	TTN	P17252	PRKCA	T20168	R20165Q	20165	Missense	distal	-3	no	17.399	14.542	EPSD	COSMIC	16.704	Loss
AGC_PKC_PKCa_PRKCA_ST	Q8WZ42	TTN	P17252	PRKCA	T20168	W20163R	20163	Missense	distal	-5	no	17.399	17.713	EPSD	COSMIC;CCLE	16.704	Up-regulation
AGC_PKC_PKCa_PRKCA_ST	Q8WZ42	TTN	P17252	PRKCA	T20168	Q20175K	20175	Missense	distal	7	no	17.399	17.454	EPSD	COSMIC	16.704	Up-regulation
AGC_PKC_PKCa_PRKCA_ST	Q8WZ42	TTN	P17252	PRKCA	T20168	A20169E	20169	Missense	proximal	1	no	17.399	16.208	EPSD	COSMIC	16.704	Loss
AGC_PKC_PKCa_PRKCA_ST	Q8WZ42	TTN	P17252	PRKCA	S20255	T20261S	20261	Missense	distal	6	no	18.384	18.432	EPSD	COSMIC	16.704	Up-regulation
AGC_PKC_PKCa_PRKCA_ST	Q8WZ42	TTN	P17252	PRKCA	S20255	V20254L	20254	Missense	proximal	-1	no	18.384	19.427	EPSD	COSMIC	16.704	Up-regulation
AGC_PKC_PKCa_PRKCA_ST	Q8WZ42	TTN	P17252	PRKCA	S20255	P20250L	20250	Missense	distal	-5	no	18.384	18.357	EPSD	COSMIC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	Q8WZ42	TTN	P17252	PRKCA	S20255	L20262V	20262	Missense	distal	7	no	18.384	18.325	EPSD	COSMIC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	Q8WZ42	TTN	P17252	PRKCA	S20255	S20255C	20255	Missense	central	0	yes	18.384	0.000	EPSD	COSMIC	16.704	Loss
AGC_PKC_PKCa_PRKCA_ST	Q8WZ42	TTN	P17252	PRKCA	S20255	G20248S	20248	Missense	distal	-7	no	18.384	18.388	EPSD	COSMIC	16.704	Up-regulation
AGC_PKC_PKCa_PRKCA_ST	Q8WZ42	TTN	P17252	PRKCA	T20307	S20301G	20301	Missense	distal	-6	no	17.676	17.642	EPSD	COSMIC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	Q8WZ42	TTN	P17252	PRKCA	T20307	T20307A	20307	Missense	central	0	yes	17.676	0.000	EPSD	COSMIC	16.704	Loss
AGC_PKC_PKCa_PRKCA_ST	Q8WZ42	TTN	P17252	PRKCA	T20307	D20314G	20314	Missense	distal	7	no	17.676	17.695	EPSD	COSMIC	16.704	Up-regulation
AGC_PKC_PKCa_PRKCA_ST	Q8WZ42	TTN	P17252	PRKCA	S20321	M20327I	20327	Missense	distal	6	no	17.902	17.869	EPSD	COSMIC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	Q8WZ42	TTN	P17252	PRKCA	S20321	M20327V	20327	Missense	distal	6	no	17.902	17.814	EPSD	COSMIC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	Q8WZ42	TTN	P17252	PRKCA	S20321	S20321N	20321	Missense	central	0	yes	17.902	0.000	EPSD	COSMIC	16.704	Loss
AGC_PKC_PKCa_PRKCA_ST	Q8WZ42	TTN	P17252	PRKCA	S20321	N20325K	20325	Missense	distal	4	no	17.902	19.029	EPSD	COSMIC	16.704	Up-regulation
AGC_PKC_PKCa_PRKCA_ST	Q8WZ42	TTN	P17252	PRKCA	S20321	K20326E	20326	Missense	distal	5	no	17.902	17.488	EPSD	COSMIC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	Q8WZ42	TTN	P17252	PRKCA	S20321	P20316T	20316	Missense	distal	-5	no	17.902	17.904	EPSD	COSMIC	16.704	Up-regulation
AGC_PKC_PKCa_PRKCA_ST	Q8WZ42	TTN	P17252	PRKCA	S20329	R20331T	20331	Missense	proximal	2	no	19.405	14.595	EPSD	COSMIC	16.704	Loss
AGC_PKC_PKCa_PRKCA_ST	Q8WZ42	TTN	P17252	PRKCA	S20329	M20327I	20327	Missense	proximal	-2	no	19.405	17.799	EPSD	COSMIC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	Q8WZ42	TTN	P17252	PRKCA	S20329	M20327V	20327	Missense	proximal	-2	no	19.405	18.545	EPSD	COSMIC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	Q8WZ42	TTN	P17252	PRKCA	S20329	A20332V	20332	Missense	distal	3	no	19.405	19.149	EPSD	COSMIC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	Q8WZ42	TTN	P17252	PRKCA	S20329	N20325K	20325	Missense	distal	-4	no	19.405	19.964	EPSD	COSMIC	16.704	Up-regulation
AGC_PKC_PKCa_PRKCA_ST	Q8WZ42	TTN	P17252	PRKCA	S20329	K20326E	20326	Missense	distal	-3	no	19.405	16.493	EPSD	COSMIC	16.704	Loss
AGC_PKC_PKCa_PRKCA_ST	Q8WZ42	TTN	P17252	PRKCA	S20864	S20864N	20864	Missense	central	0	yes	17.175	0.000	EPSD	COSMIC	16.704	Loss
AGC_PKC_PKCa_PRKCA_ST	Q8WZ42	TTN	P17252	PRKCA	S20864	L20865P	20865	Missense	proximal	1	no	17.175	16.749	EPSD	COSMIC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	Q8WZ42	TTN	P17252	PRKCA	S20868	L20865P	20865	Missense	distal	-3	no	16.415	16.922	EPSD	COSMIC	16.704	Gain
AGC_PKC_PKCa_PRKCA_ST	Q8WZ42	TTN	P17252	PRKCA	T20879	F20880L	20880	Missense	proximal	1	no	17.775	17.117	EPSD	COSMIC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	Q8WZ42	TTN	P17252	PRKCA	T20879	A20884T	20884	Missense	distal	5	no	17.775	17.497	EPSD	COSMIC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	Q8WZ42	TTN	P17252	PRKCA	T20879	A20884D	20884	Missense	distal	5	no	17.775	17.452	EPSD	COSMIC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	Q8WZ42	TTN	P17252	PRKCA	T20879	S20883I	20883	Missense	distal	4	no	17.775	16.331	EPSD	COSMIC	16.704	Loss
AGC_PKC_PKCa_PRKCA_ST	Q8WZ42	TTN	P17252	PRKCA	T21061	R21066K	21066	Missense	distal	5	no	18.302	18.446	EPSD	COSMIC	16.704	Up-regulation
AGC_PKC_PKCa_PRKCA_ST	Q8WZ42	TTN	P17252	PRKCA	T21061	T21065A	21065	Missense	distal	4	no	18.302	18.750	EPSD	COSMIC	16.704	Up-regulation
AGC_PKC_PKCa_PRKCA_ST	Q8WZ42	TTN	P17252	PRKCA	T21061	L21067F	21067	Missense	distal	6	no	18.302	18.272	EPSD	COSMIC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	Q8WZ42	TTN	P17252	PRKCA	T21061	T21060K	21060	Missense	proximal	-1	no	18.302	19.125	EPSD	COSMIC	16.704	Up-regulation
AGC_PKC_PKCa_PRKCA_ST	Q8WZ42	TTN	P17252	PRKCA	T21074	L21067F	21067	Missense	distal	-7	no	16.819	16.816	EPSD	COSMIC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	Q8WZ42	TTN	P17252	PRKCA	T21074	E21069K	21069	Missense	distal	-5	no	16.819	17.113	EPSD	COSMIC	16.704	Up-regulation
AGC_PKC_PKCa_PRKCA_ST	Q8WZ42	TTN	P17252	PRKCA	S21339	P21336S	21336	Missense	distal	-3	no	16.091	17.070	EPSD	COSMIC	16.704	Gain
AGC_PKC_PKCa_PRKCA_ST	Q8WZ42	TTN	P17252	PRKCA	S21604	G21601R	21601	Missense	distal	-3	no	14.136	17.397	EPSD	COSMIC;CCLE	16.704	Gain
AGC_PKC_PKCa_PRKCA_ST	Q8WZ42	TTN	P17252	PRKCA	T21612	T21609M	21609	Missense	distal	-3	no	16.583	17.774	EPSD	COSMIC	16.704	Gain
AGC_PKC_PKCa_PRKCA_ST	Q8WZ42	TTN	P17252	PRKCA	T21612	T21611S	21611	Missense	proximal	-1	no	16.583	16.962	EPSD	COSMIC	16.704	Gain
AGC_PKC_PKCa_PRKCA_ST	Q8WZ42	TTN	P17252	PRKCA	T21769	K21771E	21771	Missense	proximal	2	no	17.390	12.111	EPSD	COSMIC	16.704	Loss
AGC_PKC_PKCa_PRKCA_ST	Q8WZ42	TTN	P17252	PRKCA	T21769	E21763Q	21763	Missense	distal	-6	no	17.390	17.321	EPSD	COSMIC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	Q8WZ42	TTN	P17252	PRKCA	T21769	G21770D	21770	Missense	proximal	1	no	17.390	16.744	EPSD	COSMIC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	Q8WZ42	TTN	P17252	PRKCA	T21769	I21776T	21776	Missense	distal	7	no	17.390	17.550	EPSD	COSMIC	16.704	Up-regulation
AGC_PKC_PKCa_PRKCA_ST	Q8WZ42	TTN	P17252	PRKCA	T21769	G21770V	21770	Missense	proximal	1	no	17.390	18.121	EPSD	COSMIC;CCLE	16.704	Up-regulation
AGC_PKC_PKCa_PRKCA_ST	Q8WZ42	TTN	P17252	PRKCA	T21837	I21830M	21830	Missense	distal	-7	no	16.917	16.929	EPSD	COSMIC	16.704	Up-regulation
AGC_PKC_PKCa_PRKCA_ST	Q8WZ42	TTN	P17252	PRKCA	T21837	R21838P	21838	Missense	proximal	1	no	16.917	16.143	EPSD	COSMIC	16.704	Loss
AGC_PKC_PKCa_PRKCA_ST	Q8WZ42	TTN	P17252	PRKCA	T21837	S21840C	21840	Missense	distal	3	no	16.917	15.690	EPSD	COSMIC	16.704	Loss
AGC_PKC_PKCa_PRKCA_ST	Q8WZ42	TTN	P17252	PRKCA	T21837	S21842A	21842	Missense	distal	5	no	16.917	17.020	EPSD	COSMIC	16.704	Up-regulation
AGC_PKC_PKCa_PRKCA_ST	Q8WZ42	TTN	P17252	PRKCA	T21837	A21844T	21844	Missense	distal	7	no	16.917	16.926	EPSD	COSMIC	16.704	Up-regulation
AGC_PKC_PKCa_PRKCA_ST	Q8WZ42	TTN	P17252	PRKCA	S21840	K21847E	21847	Missense	distal	7	no	17.035	16.889	EPSD	COSMIC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	Q8WZ42	TTN	P17252	PRKCA	S21840	T21845I	21845	Missense	distal	5	no	17.035	17.017	EPSD	COSMIC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	Q8WZ42	TTN	P17252	PRKCA	S21840	R21838P	21838	Missense	proximal	-2	no	17.035	13.993	EPSD	COSMIC	16.704	Loss
AGC_PKC_PKCa_PRKCA_ST	Q8WZ42	TTN	P17252	PRKCA	S21840	S21840C	21840	Missense	central	0	yes	17.035	0.000	EPSD	COSMIC	16.704	Loss
AGC_PKC_PKCa_PRKCA_ST	Q8WZ42	TTN	P17252	PRKCA	S21840	S21842A	21842	Missense	proximal	2	no	17.035	16.956	EPSD	COSMIC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	Q8WZ42	TTN	P17252	PRKCA	S21840	A21844T	21844	Missense	distal	4	no	17.035	16.588	EPSD	COSMIC	16.704	Loss
AGC_PKC_PKCa_PRKCA_ST	Q8WZ42	TTN	P17252	PRKCA	S21842	S21840C	21840	Missense	proximal	-2	no	15.217	16.819	EPSD	COSMIC	16.704	Gain
AGC_PKC_PKCa_PRKCA_ST	Q8WZ42	TTN	P17252	PRKCA	T22191	Q22193R	22193	Missense	proximal	2	no	13.240	17.074	EPSD	COSMIC	16.704	Gain
AGC_PKC_PKCa_PRKCA_ST	Q8WZ42	TTN	P17252	PRKCA	S22272	A22266T	22266	Missense	distal	-6	no	17.084	16.996	EPSD	COSMIC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	Q8WZ42	TTN	P17252	PRKCA	S22456	R22454K	22454	Missense	proximal	-2	no	17.421	15.793	EPSD	COSMIC	16.704	Loss
AGC_PKC_PKCa_PRKCA_ST	Q8WZ42	TTN	P17252	PRKCA	S22456	G22457C	22457	Missense	proximal	1	no	17.421	15.538	EPSD	COSMIC	16.704	Loss
AGC_PKC_PKCa_PRKCA_ST	Q8WZ42	TTN	P17252	PRKCA	S22456	S22456L	22456	Missense	central	0	yes	17.421	0.000	EPSD	COSMIC	16.704	Loss
AGC_PKC_PKCa_PRKCA_ST	Q8WZ42	TTN	P17252	PRKCA	S22828	G22826R	22826	Missense	proximal	-2	no	13.901	16.773	EPSD	COSMIC	16.704	Gain
AGC_PKC_PKCa_PRKCA_ST	Q8WZ42	TTN	P17252	PRKCA	S22853	I22857T	22857	Missense	distal	4	no	18.207	19.220	EPSD	COSMIC	16.704	Up-regulation
AGC_PKC_PKCa_PRKCA_ST	Q8WZ42	TTN	P17252	PRKCA	S22853	N22847S	22847	Missense	distal	-6	no	18.207	18.264	EPSD	COSMIC	16.704	Up-regulation
AGC_PKC_PKCa_PRKCA_ST	Q8WZ42	TTN	P17252	PRKCA	S22853	D22852G	22852	Missense	proximal	-1	no	18.207	18.950	EPSD	COSMIC	16.704	Up-regulation
AGC_PKC_PKCa_PRKCA_ST	Q8WZ42	TTN	P17252	PRKCA	S22853	L22858F	22858	Missense	distal	5	no	18.207	18.431	EPSD	COSMIC	16.704	Up-regulation
AGC_PKC_PKCa_PRKCA_ST	Q8WZ42	TTN	P17252	PRKCA	S22853	G22846E	22846	Missense	distal	-7	no	18.207	18.203	EPSD	COSMIC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	Q8WZ42	TTN	P17252	PRKCA	S22853	F22851L	22851	Missense	proximal	-2	no	18.207	19.492	EPSD	COSMIC;CCLE	16.704	Up-regulation
AGC_PKC_PKCa_PRKCA_ST	Q8WZ42	TTN	P17252	PRKCA	S22969	P22976S	22976	Missense	distal	7	no	17.239	17.202	EPSD	COSMIC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	Q8WZ42	TTN	P17252	PRKCA	S23063	P23065T	23065	Missense	proximal	2	no	18.677	19.069	EPSD	COSMIC	16.704	Up-regulation
AGC_PKC_PKCa_PRKCA_ST	Q8WZ42	TTN	P17252	PRKCA	S23063	V23066M	23066	Missense	distal	3	no	18.677	19.262	EPSD	COSMIC	16.704	Up-regulation
AGC_PKC_PKCa_PRKCA_ST	Q8WZ42	TTN	P17252	PRKCA	S23063	P23065S	23065	Missense	proximal	2	no	18.677	19.259	EPSD	COSMIC	16.704	Up-regulation
AGC_PKC_PKCa_PRKCA_ST	Q8WZ42	TTN	P17252	PRKCA	S23125	E23127K	23127	Missense	proximal	2	no	11.633	16.913	EPSD	COSMIC	16.704	Gain
AGC_PKC_PKCa_PRKCA_ST	Q8WZ42	TTN	P17252	PRKCA	T23133	E23127K	23127	Missense	distal	-6	no	16.803	16.870	EPSD	COSMIC	16.704	Up-regulation
AGC_PKC_PKCa_PRKCA_ST	Q8WZ42	TTN	P17252	PRKCA	T23133	K23135T	23135	Missense	proximal	2	no	16.803	12.414	EPSD	COSMIC	16.704	Loss
AGC_PKC_PKCa_PRKCA_ST	Q8WZ42	TTN	P17252	PRKCA	T23226	A23223T	23223	Missense	distal	-3	no	17.741	18.026	EPSD	COSMIC	16.704	Up-regulation
AGC_PKC_PKCa_PRKCA_ST	Q8WZ42	TTN	P17252	PRKCA	T23226	I23227V	23227	Missense	proximal	1	no	17.741	17.029	EPSD	COSMIC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	Q8WZ42	TTN	P17252	PRKCA	T23226	A23229V	23229	Missense	distal	3	no	17.741	17.484	EPSD	COSMIC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	Q8WZ42	TTN	P17252	PRKCA	T23226	R23224K	23224	Missense	proximal	-2	no	17.741	16.113	EPSD	COSMIC	16.704	Loss
AGC_PKC_PKCa_PRKCA_ST	Q8WZ42	TTN	P17252	PRKCA	T23226	K23233E	23233	Missense	distal	7	no	17.741	17.595	EPSD	COSMIC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	Q8WZ42	TTN	P17252	PRKCA	T23226	A23223V	23223	Missense	distal	-3	no	17.741	18.500	EPSD	COSMIC	16.704	Up-regulation
AGC_PKC_PKCa_PRKCA_ST	Q8WZ42	TTN	P17252	PRKCA	S23279	V23276A	23276	Missense	distal	-3	no	17.437	16.678	EPSD	COSMIC	16.704	Loss
AGC_PKC_PKCa_PRKCA_ST	Q8WZ42	TTN	P17252	PRKCA	S23279	D23282N	23282	Missense	distal	3	no	17.437	17.592	EPSD	COSMIC;CCLE	16.704	Up-regulation
AGC_PKC_PKCa_PRKCA_ST	Q8WZ42	TTN	P17252	PRKCA	S23381	L23384R	23384	Missense	distal	3	no	15.145	17.383	EPSD	COSMIC	16.704	Gain
AGC_PKC_PKCa_PRKCA_ST	Q8WZ42	TTN	P17252	PRKCA	S24112	L24113I	24113	Missense	proximal	1	no	17.365	18.201	EPSD	COSMIC	16.704	Up-regulation
AGC_PKC_PKCa_PRKCA_ST	Q8WZ42	TTN	P17252	PRKCA	S24112	L24113P	24113	Missense	proximal	1	no	17.365	16.938	EPSD	COSMIC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	Q8WZ42	TTN	P17252	PRKCA	T24542	G24539R	24539	Missense	distal	-3	no	13.533	16.795	EPSD	COSMIC	16.704	Gain
AGC_PKC_PKCa_PRKCA_ST	Q8WZ42	TTN	P17252	PRKCA	T24688	A24692V	24692	Missense	distal	4	no	18.197	16.860	EPSD	COSMIC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	Q8WZ42	TTN	P17252	PRKCA	T24688	S24689I	24689	Missense	proximal	1	no	18.197	19.860	EPSD	COSMIC	16.704	Up-regulation
AGC_PKC_PKCa_PRKCA_ST	Q8WZ42	TTN	P17252	PRKCA	T24688	A24692T	24692	Missense	distal	4	no	18.197	17.750	EPSD	COSMIC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	Q8WZ42	TTN	P17252	PRKCA	S24788	G24789R	24789	Missense	proximal	1	no	17.209	18.162	EPSD	COSMIC	16.704	Up-regulation
AGC_PKC_PKCa_PRKCA_ST	Q8WZ42	TTN	P17252	PRKCA	S24788	C24795R	24795	Missense	distal	7	no	17.209	17.432	EPSD	COSMIC	16.704	Up-regulation
AGC_PKC_PKCa_PRKCA_ST	Q8WZ42	TTN	P17252	PRKCA	T24801	R24806H	24806	Missense	distal	5	no	17.149	16.890	EPSD	COSMIC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	Q8WZ42	TTN	P17252	PRKCA	T24801	R24806C	24806	Missense	distal	5	no	17.149	16.418	EPSD	COSMIC	16.704	Loss
AGC_PKC_PKCa_PRKCA_ST	Q8WZ42	TTN	P17252	PRKCA	T24801	R24799C	24799	Missense	proximal	-2	no	17.149	15.450	EPSD	COSMIC	16.704	Loss
AGC_PKC_PKCa_PRKCA_ST	Q8WZ42	TTN	P17252	PRKCA	T24801	R24804C	24804	Missense	distal	3	no	17.149	14.531	EPSD	COSMIC	16.704	Loss
AGC_PKC_PKCa_PRKCA_ST	Q8WZ42	TTN	P17252	PRKCA	T24801	C24795R	24795	Missense	distal	-6	no	17.149	17.519	EPSD	COSMIC	16.704	Up-regulation
AGC_PKC_PKCa_PRKCA_ST	Q8WZ42	TTN	P17252	PRKCA	T24801	K24797N	24797	Missense	distal	-4	no	17.149	16.591	EPSD	COSMIC	16.704	Loss
AGC_PKC_PKCa_PRKCA_ST	Q8WZ42	TTN	P17252	PRKCA	S25442	V25440I	25440	Missense	proximal	-2	no	16.953	16.207	EPSD	COSMIC	16.704	Loss
AGC_PKC_PKCa_PRKCA_ST	Q8WZ42	TTN	P17252	PRKCA	T25624	I25623N	25623	Missense	proximal	-1	no	15.890	17.016	EPSD	COSMIC	16.704	Gain
AGC_PKC_PKCa_PRKCA_ST	Q8WZ42	TTN	P17252	PRKCA	T25701	G25703R	25703	Missense	proximal	2	no	12.335	17.580	EPSD	COSMIC	16.704	Gain
AGC_PKC_PKCa_PRKCA_ST	Q8WZ42	TTN	P17252	PRKCA	S26266	K26268N	26268	Missense	proximal	2	no	17.213	12.264	EPSD	COSMIC	16.704	Loss
AGC_PKC_PKCa_PRKCA_ST	Q8WZ42	TTN	P17252	PRKCA	S26266	G26265W	26265	Missense	proximal	-1	no	17.213	15.768	EPSD	COSMIC	16.704	Loss
AGC_PKC_PKCa_PRKCA_ST	Q8WZ42	TTN	P17252	PRKCA	S26266	G26265R	26265	Missense	proximal	-1	no	17.213	17.352	EPSD	COSMIC	16.704	Up-regulation
AGC_PKC_PKCa_PRKCA_ST	Q8WZ42	TTN	P17252	PRKCA	S26380	S26380Y	26380	Missense	central	0	yes	17.875	0.000	EPSD	COSMIC	16.704	Loss
AGC_PKC_PKCa_PRKCA_ST	Q8WZ42	TTN	P17252	PRKCA	S26380	K26374N	26374	Missense	distal	-6	no	17.875	17.752	EPSD	COSMIC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	Q8WZ42	TTN	P17252	PRKCA	S26472	A26467T	26467	Missense	distal	-5	no	16.863	17.244	EPSD	COSMIC	16.704	Up-regulation
AGC_PKC_PKCa_PRKCA_ST	Q8WZ42	TTN	P17252	PRKCA	S26472	R26477C	26477	Missense	distal	5	no	16.863	16.131	EPSD	COSMIC	16.704	Loss
AGC_PKC_PKCa_PRKCA_ST	Q8WZ42	TTN	P17252	PRKCA	S26472	I26475T	26475	Missense	distal	3	no	16.863	17.576	EPSD	COSMIC	16.704	Up-regulation
AGC_PKC_PKCa_PRKCA_ST	Q8WZ42	TTN	P17252	PRKCA	S26472	A26469D	26469	Missense	distal	-3	no	16.863	16.270	EPSD	COSMIC	16.704	Loss
AGC_PKC_PKCa_PRKCA_ST	Q8WZ42	TTN	P17252	PRKCA	S26627	T26621M	26621	Missense	distal	-6	no	17.672	17.794	EPSD	COSMIC	16.704	Up-regulation
AGC_PKC_PKCa_PRKCA_ST	Q8WZ42	TTN	P17252	PRKCA	S26627	S26627F	26627	Missense	central	0	yes	17.672	0.000	EPSD	COSMIC	16.704	Loss
AGC_PKC_PKCa_PRKCA_ST	Q8WZ42	TTN	P17252	PRKCA	S26627	S26627L	26627	Missense	central	0	yes	17.672	0.000	EPSD	COSMIC	16.704	Loss
AGC_PKC_PKCa_PRKCA_ST	Q8WZ42	TTN	P17252	PRKCA	S26629	S26627F	26627	Missense	proximal	-2	no	18.523	17.852	EPSD	COSMIC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	Q8WZ42	TTN	P17252	PRKCA	S26629	S26627L	26627	Missense	proximal	-2	no	18.523	19.137	EPSD	COSMIC	16.704	Up-regulation
AGC_PKC_PKCa_PRKCA_ST	Q8WZ42	TTN	P17252	PRKCA	S27063	S27060F	27060	Missense	distal	-3	no	18.349	18.598	EPSD	COSMIC	16.704	Up-regulation
AGC_PKC_PKCa_PRKCA_ST	Q8WZ42	TTN	P17252	PRKCA	S27262	K27264N	27264	Missense	proximal	2	no	17.720	12.771	EPSD	COSMIC	16.704	Loss
AGC_PKC_PKCa_PRKCA_ST	Q8WZ42	TTN	P17252	PRKCA	T27299	P27302S	27302	Missense	distal	3	no	16.665	16.805	EPSD	COSMIC	16.704	Gain
AGC_PKC_PKCa_PRKCA_ST	Q8WZ42	TTN	P17252	PRKCA	T28046	E28045K	28045	Missense	proximal	-1	no	18.632	19.058	EPSD	COSMIC	16.704	Up-regulation
AGC_PKC_PKCa_PRKCA_ST	Q8WZ42	TTN	P17252	PRKCA	S28144	V28149A	28149	Missense	distal	5	no	16.478	16.862	EPSD	COSMIC	16.704	Gain
AGC_PKC_PKCa_PRKCA_ST	Q8WZ42	TTN	P17252	PRKCA	S28144	W28140R	28140	Missense	distal	-4	no	16.478	17.304	EPSD	COSMIC;CCLE	16.704	Gain
AGC_PKC_PKCa_PRKCA_ST	Q8WZ42	TTN	P17252	PRKCA	S28144	V28143L	28143	Missense	proximal	-1	no	16.478	17.521	EPSD	COSMIC	16.704	Gain
AGC_PKC_PKCa_PRKCA_ST	Q8WZ42	TTN	P17252	PRKCA	S28144	T28145I	28145	Missense	proximal	1	no	16.478	17.814	EPSD	COSMIC	16.704	Gain
AGC_PKC_PKCa_PRKCA_ST	Q8WZ42	TTN	P17252	PRKCA	S28144	V28143M	28143	Missense	proximal	-1	no	16.478	18.600	EPSD	COSMIC	16.704	Gain
AGC_PKC_PKCa_PRKCA_ST	Q8WZ42	TTN	P17252	PRKCA	S28286	P28280L	28280	Missense	distal	-6	no	18.189	18.155	EPSD	COSMIC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	Q8WZ42	TTN	P17252	PRKCA	S28397	P28392S	28392	Missense	distal	-5	no	20.692	20.367	EPSD	COSMIC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	Q8WZ42	TTN	P17252	PRKCA	S28397	R28394H	28394	Missense	distal	-3	no	20.692	16.836	EPSD	COSMIC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	Q8WZ42	TTN	P17252	PRKCA	S28397	K28403E	28403	Missense	distal	6	no	20.692	20.598	EPSD	COSMIC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	Q8WZ42	TTN	P17252	PRKCA	S28397	I28393L	28393	Missense	distal	-4	no	20.692	20.703	EPSD	COSMIC	16.704	Up-regulation
AGC_PKC_PKCa_PRKCA_ST	Q8WZ42	TTN	P17252	PRKCA	S28397	D28395N	28395	Missense	proximal	-2	no	20.692	20.914	EPSD	COSMIC	16.704	Up-regulation
AGC_PKC_PKCa_PRKCA_ST	Q8WZ42	TTN	P17252	PRKCA	S28540	E28535K	28535	Missense	distal	-5	no	16.943	17.237	EPSD	COSMIC;CCLE	16.704	Up-regulation
AGC_PKC_PKCa_PRKCA_ST	Q8WZ42	TTN	P17252	PRKCA	S28540	V28537I	28537	Missense	distal	-3	no	16.943	16.145	EPSD	COSMIC	16.704	Loss
AGC_PKC_PKCa_PRKCA_ST	Q8WZ42	TTN	P17252	PRKCA	S28540	E28533K	28533	Missense	distal	-7	no	16.943	16.951	EPSD	COSMIC;CCLE	16.704	Up-regulation
AGC_PKC_PKCa_PRKCA_ST	Q8WZ42	TTN	P17252	PRKCA	S28549	K28554R	28554	Missense	distal	5	no	18.929	18.785	EPSD	COSMIC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	Q8WZ42	TTN	P17252	PRKCA	S28549	A28553T	28553	Missense	distal	4	no	18.929	18.482	EPSD	COSMIC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	Q8WZ42	TTN	P17252	PRKCA	S28637	T28641M	28641	Missense	distal	4	no	17.529	18.011	EPSD	COSMIC	16.704	Up-regulation
AGC_PKC_PKCa_PRKCA_ST	Q8WZ42	TTN	P17252	PRKCA	S28637	S28636P	28636	Missense	proximal	-1	no	17.529	17.230	EPSD	COSMIC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	Q8WZ42	TTN	P17252	PRKCA	S28739	A28745G	28745	Missense	distal	6	no	17.529	17.421	EPSD	COSMIC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	Q8WZ42	TTN	P17252	PRKCA	S28739	R28741K	28741	Missense	proximal	2	no	17.529	17.107	EPSD	COSMIC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	Q8WZ42	TTN	P17252	PRKCA	S28902	R28904I	28904	Missense	proximal	2	no	19.276	14.244	EPSD	COSMIC	16.704	Loss
AGC_PKC_PKCa_PRKCA_ST	Q8WZ42	TTN	P17252	PRKCA	S28902	L28908F	28908	Missense	distal	6	no	19.276	19.245	EPSD	COSMIC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	Q8WZ42	TTN	P17252	PRKCA	S28902	G28900E	28900	Missense	proximal	-2	no	19.276	18.022	EPSD	COSMIC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	Q8WZ42	TTN	P17252	PRKCA	S28966	I28971N	28971	Missense	distal	5	no	18.220	18.193	EPSD	COSMIC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	Q8WZ42	TTN	P17252	PRKCA	S28966	A28963V	28963	Missense	distal	-3	no	18.220	18.979	EPSD	COSMIC	16.704	Up-regulation
AGC_PKC_PKCa_PRKCA_ST	Q8WZ42	TTN	P17252	PRKCA	S29104	G29106R	29106	Missense	proximal	2	no	16.684	21.929	EPSD	COSMIC	16.704	Gain
AGC_PKC_PKCa_PRKCA_ST	Q8WZ42	TTN	P17252	PRKCA	S29104	T29098A	29098	Missense	distal	-6	no	16.684	16.773	EPSD	COSMIC	16.704	Gain
AGC_PKC_PKCa_PRKCA_ST	Q8WZ42	TTN	P17252	PRKCA	S29104	G29106S	29106	Missense	proximal	2	no	16.684	17.310	EPSD	COSMIC	16.704	Gain
AGC_PKC_PKCa_PRKCA_ST	Q8WZ42	TTN	P17252	PRKCA	S29104	E29109K	29109	Missense	distal	5	no	16.684	17.098	EPSD	COSMIC	16.704	Gain
AGC_PKC_PKCa_PRKCA_ST	Q8WZ42	TTN	P17252	PRKCA	T29272	T29272K	29272	Missense	central	0	yes	16.908	0.000	EPSD	COSMIC;CCLE	16.704	Loss
AGC_PKC_PKCa_PRKCA_ST	Q8WZ42	TTN	P17252	PRKCA	S29301	G29299V	29299	Missense	proximal	-2	no	17.050	17.080	EPSD	COSMIC	16.704	Up-regulation
AGC_PKC_PKCa_PRKCA_ST	Q8WZ42	TTN	P17252	PRKCA	S29301	F29305V	29305	Missense	distal	4	no	17.050	16.090	EPSD	COSMIC	16.704	Loss
AGC_PKC_PKCa_PRKCA_ST	Q8WZ42	TTN	P17252	PRKCA	S29421	E29427K	29427	Missense	distal	6	no	17.037	17.131	EPSD	COSMIC	16.704	Up-regulation
AGC_PKC_PKCa_PRKCA_ST	Q8WZ42	TTN	P17252	PRKCA	S29421	S29426R	29426	Missense	distal	5	no	17.037	17.179	EPSD	COSMIC	16.704	Up-regulation
AGC_PKC_PKCa_PRKCA_ST	Q8WZ42	TTN	P17252	PRKCA	S29637	D29636N	29636	Missense	proximal	-1	no	19.038	19.376	EPSD	COSMIC	16.704	Up-regulation
AGC_PKC_PKCa_PRKCA_ST	Q8WZ42	TTN	P17252	PRKCA	S29637	G29643E	29643	Missense	distal	6	no	19.038	19.081	EPSD	COSMIC	16.704	Up-regulation
AGC_PKC_PKCa_PRKCA_ST	Q8WZ42	TTN	P17252	PRKCA	S29642	D29636N	29636	Missense	distal	-6	no	17.761	17.788	EPSD	COSMIC	16.704	Up-regulation
AGC_PKC_PKCa_PRKCA_ST	Q8WZ42	TTN	P17252	PRKCA	S29642	G29643E	29643	Missense	proximal	1	no	17.761	17.147	EPSD	COSMIC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	Q8WZ42	TTN	P17252	PRKCA	S29642	Y29645H	29645	Missense	distal	3	no	17.761	19.316	EPSD	COSMIC	16.704	Up-regulation
AGC_PKC_PKCa_PRKCA_ST	Q8WZ42	TTN	P17252	PRKCA	S29710	G29711S	29711	Missense	proximal	1	no	16.860	16.640	EPSD	COSMIC	16.704	Loss
AGC_PKC_PKCa_PRKCA_ST	Q8WZ42	TTN	P17252	PRKCA	S29710	I29704M	29704	Missense	distal	-6	no	16.860	16.954	EPSD	COSMIC	16.704	Up-regulation
AGC_PKC_PKCa_PRKCA_ST	Q8WZ42	TTN	P17252	PRKCA	S29710	R29708T	29708	Missense	proximal	-2	no	16.860	13.967	EPSD	COSMIC	16.704	Loss
AGC_PKC_PKCa_PRKCA_ST	Q8WZ42	TTN	P17252	PRKCA	S29710	R29708K	29708	Missense	proximal	-2	no	16.860	15.233	EPSD	COSMIC	16.704	Loss
AGC_PKC_PKCa_PRKCA_ST	Q8WZ42	TTN	P17252	PRKCA	S29721	K29723N	29723	Missense	proximal	2	no	19.457	14.508	EPSD	COSMIC	16.704	Loss
AGC_PKC_PKCa_PRKCA_ST	Q8WZ42	TTN	P17252	PRKCA	S29721	V29722D	29722	Missense	proximal	1	no	19.457	18.081	EPSD	COSMIC;CCLE	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	Q8WZ42	TTN	P17252	PRKCA	S29721	R29724C	29724	Missense	distal	3	no	19.457	16.839	EPSD	COSMIC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	Q8WZ42	TTN	P17252	PRKCA	S29721	S29721N	29721	Missense	central	0	yes	19.457	0.000	EPSD	COSMIC	16.704	Loss
AGC_PKC_PKCa_PRKCA_ST	Q8WZ42	TTN	P17252	PRKCA	S29721	V29722L	29722	Missense	proximal	1	no	19.457	19.332	EPSD	COSMIC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	Q8WZ42	TTN	P17252	PRKCA	S29721	S29720F	29720	Missense	proximal	-1	no	19.457	18.750	EPSD	COSMIC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	Q8WZ42	TTN	P17252	PRKCA	S29785	S29785P	29785	Missense	central	0	yes	19.319	0.000	EPSD	COSMIC	16.704	Loss
AGC_PKC_PKCa_PRKCA_ST	Q8WZ42	TTN	P17252	PRKCA	T30026	Y30025F	30025	Missense	proximal	-1	no	17.346	17.088	EPSD	COSMIC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	Q8WZ42	TTN	P17252	PRKCA	T30384	G30388M	30388	Missense	distal	4	no	18.029	18.437	EPSD	COSMIC	16.704	Up-regulation
AGC_PKC_PKCa_PRKCA_ST	Q8WZ42	TTN	P17252	PRKCA	S30470	D30463N	30463	Missense	distal	-7	no	19.760	19.759	EPSD	COSMIC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	Q8WZ42	TTN	P17252	PRKCA	S30709	R30711C	30711	Missense	proximal	2	no	19.787	15.437	EPSD	COSMIC;CCLE	16.704	Loss
AGC_PKC_PKCa_PRKCA_ST	Q8WZ42	TTN	P17252	PRKCA	S30709	R30711S	30711	Missense	proximal	2	no	19.787	15.167	EPSD	COSMIC	16.704	Loss
AGC_PKC_PKCa_PRKCA_ST	Q8WZ42	TTN	P17252	PRKCA	S30709	E30710Q	30710	Missense	proximal	1	no	19.787	21.237	EPSD	COSMIC	16.704	Up-regulation
AGC_PKC_PKCa_PRKCA_ST	Q8WZ42	TTN	P17252	PRKCA	S30709	R30711H	30711	Missense	proximal	2	no	19.787	14.763	EPSD	COSMIC	16.704	Loss
AGC_PKC_PKCa_PRKCA_ST	Q8WZ42	TTN	P17252	PRKCA	S30855	C30852Y	30852	Missense	distal	-3	no	21.185	19.364	EPSD	COSMIC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	Q8WZ42	TTN	P17252	PRKCA	S30855	R30853H	30853	Missense	proximal	-2	no	21.185	16.631	EPSD	COSMIC	16.704	Loss
AGC_PKC_PKCa_PRKCA_ST	Q8WZ42	TTN	P17252	PRKCA	S30855	R30853C	30853	Missense	proximal	-2	no	21.185	19.485	EPSD	COSMIC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	Q8WZ42	TTN	P17252	PRKCA	S30855	R30857G	30857	Missense	proximal	2	no	21.185	15.939	EPSD	COSMIC	16.704	Loss
AGC_PKC_PKCa_PRKCA_ST	Q8WZ42	TTN	P17252	PRKCA	S30941	G30940V	30940	Missense	proximal	-1	no	18.309	16.599	EPSD	COSMIC	16.704	Loss
AGC_PKC_PKCa_PRKCA_ST	Q8WZ42	TTN	P17252	PRKCA	S30941	R30946C	30946	Missense	distal	5	no	18.309	17.578	EPSD	COSMIC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	Q8WZ42	TTN	P17252	PRKCA	S30941	R30946H	30946	Missense	distal	5	no	18.309	18.050	EPSD	COSMIC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	Q8WZ42	TTN	P17252	PRKCA	T31020	E31018K	31018	Missense	proximal	-2	no	15.284	17.783	EPSD	COSMIC	16.704	Gain
AGC_PKC_PKCa_PRKCA_ST	Q8WZ42	TTN	P17252	PRKCA	T31020	E31018Q	31018	Missense	proximal	-2	no	15.284	17.652	EPSD	COSMIC	16.704	Gain
AGC_PKC_PKCa_PRKCA_ST	Q8WZ42	TTN	P17252	PRKCA	S31105	D31103N	31103	Missense	proximal	-2	no	19.021	19.243	EPSD	COSMIC	16.704	Up-regulation
AGC_PKC_PKCa_PRKCA_ST	Q8WZ42	TTN	P17252	PRKCA	S31105	K31099E	31099	Missense	distal	-6	no	19.021	18.954	EPSD	COSMIC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	Q8WZ42	TTN	P17252	PRKCA	S31157	E31159K	31159	Missense	proximal	2	no	12.754	18.033	EPSD	COSMIC	16.704	Gain
AGC_PKC_PKCa_PRKCA_ST	Q8WZ42	TTN	P17252	PRKCA	S31449	L31454I	31454	Missense	distal	5	no	20.611	20.608	EPSD	COSMIC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	Q8WZ42	TTN	P17252	PRKCA	S31449	R31444C	31444	Missense	distal	-5	no	20.611	19.936	EPSD	COSMIC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	Q8WZ42	TTN	P17252	PRKCA	S31449	R31445K	31445	Missense	distal	-4	no	20.611	20.647	EPSD	COSMIC	16.704	Up-regulation
AGC_PKC_PKCa_PRKCA_ST	Q8WZ42	TTN	P17252	PRKCA	S31449	P31443L	31443	Missense	distal	-6	no	20.611	20.578	EPSD	COSMIC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	Q8WZ42	TTN	P17252	PRKCA	S31509	M31508T	31508	Missense	proximal	-1	no	17.357	16.319	EPSD	COSMIC	16.704	Loss
AGC_PKC_PKCa_PRKCA_ST	Q8WZ42	TTN	P17252	PRKCA	S31509	T31514A	31514	Missense	distal	5	no	17.357	17.635	EPSD	COSMIC	16.704	Up-regulation
AGC_PKC_PKCa_PRKCA_ST	Q8WZ42	TTN	P17252	PRKCA	S31510	T31514A	31514	Missense	distal	4	no	16.662	17.109	EPSD	COSMIC	16.704	Gain
AGC_PKC_PKCa_PRKCA_ST	Q8WZ42	TTN	P17252	PRKCA	S32312	T32308I	32308	Missense	distal	-4	no	18.878	19.098	EPSD	COSMIC	16.704	Up-regulation
AGC_PKC_PKCa_PRKCA_ST	Q8WZ42	TTN	P17252	PRKCA	T32313	T32308I	32308	Missense	distal	-5	no	16.965	16.493	EPSD	COSMIC	16.704	Loss
AGC_PKC_PKCa_PRKCA_ST	Q8WZ42	TTN	P17252	PRKCA	S32478	G32481E	32481	Missense	distal	3	no	18.634	18.035	EPSD	COSMIC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	Q8WZ42	TTN	P17252	PRKCA	S32478	G32474S	32474	Missense	distal	-4	no	18.634	18.542	EPSD	COSMIC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	Q8WZ42	TTN	P17252	PRKCA	S32478	C32472F	32472	Missense	distal	-6	no	18.634	18.845	EPSD	COSMIC	16.704	Up-regulation
AGC_PKC_PKCa_PRKCA_ST	Q8WZ42	TTN	P17252	PRKCA	S32478	G32481A	32481	Missense	distal	3	no	18.634	17.676	EPSD	COSMIC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	Q8WZ42	TTN	P17252	PRKCA	S32478	S32483F	32483	Missense	distal	5	no	18.634	18.668	EPSD	COSMIC	16.704	Up-regulation
AGC_PKC_PKCa_PRKCA_ST	Q8WZ42	TTN	P17252	PRKCA	T32599	Y32592H	32592	Missense	distal	-7	no	18.926	18.925	EPSD	COSMIC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	Q8WZ42	TTN	P17252	PRKCA	T32599	M32600V	32600	Missense	proximal	1	no	18.926	19.266	EPSD	COSMIC	16.704	Up-regulation
AGC_PKC_PKCa_PRKCA_ST	Q8WZ42	TTN	P17252	PRKCA	T32599	K32601N	32601	Missense	proximal	2	no	18.926	13.977	EPSD	COSMIC	16.704	Loss
AGC_PKC_PKCa_PRKCA_ST	Q8WZ42	TTN	P17252	PRKCA	T32599	R32606H	32606	Missense	distal	7	no	18.926	18.855	EPSD	COSMIC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	Q8WZ42	TTN	P17252	PRKCA	T32609	R32606H	32606	Missense	distal	-3	no	17.831	13.975	EPSD	COSMIC	16.704	Loss
AGC_PKC_PKCa_PRKCA_ST	Q8WZ42	TTN	P17252	PRKCA	S32702	E32700K	32700	Missense	proximal	-2	no	14.246	16.745	EPSD	COSMIC	16.704	Gain
AGC_PKC_PKCa_PRKCA_ST	Q8WZ42	TTN	P17252	PRKCA	T32839	M32842V	32842	Missense	distal	3	no	17.494	16.908	EPSD	COSMIC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	Q8WZ42	TTN	P17252	PRKCA	T32998	V32991A	32991	Missense	distal	-7	no	18.039	18.049	EPSD	COSMIC	16.704	Up-regulation
AGC_PKC_PKCa_PRKCA_ST	Q8WZ42	TTN	P17252	PRKCA	T32998	P32999H	32999	Missense	proximal	1	no	18.039	18.000	EPSD	COSMIC;CCLE	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	Q8WZ42	TTN	P17252	PRKCA	S33013	E33020K	33020	Missense	distal	7	no	20.242	20.388	EPSD	COSMIC	16.704	Up-regulation
AGC_PKC_PKCa_PRKCA_ST	Q8WZ42	TTN	P17252	PRKCA	S33088	R33086K	33086	Missense	proximal	-2	no	17.091	15.463	EPSD	COSMIC	16.704	Loss
AGC_PKC_PKCa_PRKCA_ST	Q8WZ42	TTN	P17252	PRKCA	S33088	T33094M	33094	Missense	distal	6	no	17.091	17.138	EPSD	COSMIC	16.704	Up-regulation
AGC_PKC_PKCa_PRKCA_ST	Q8WZ42	TTN	P17252	PRKCA	S33088	Y33090D	33090	Missense	proximal	2	no	17.091	16.307	EPSD	COSMIC	16.704	Loss
AGC_PKC_PKCa_PRKCA_ST	Q8WZ42	TTN	P17252	PRKCA	S33158	Q33165R	33165	Missense	distal	7	no	18.321	18.325	EPSD	COSMIC	16.704	Up-regulation
AGC_PKC_PKCa_PRKCA_ST	Q8WZ42	TTN	P17252	PRKCA	S33158	S33158F	33158	Missense	central	0	yes	18.321	0.000	EPSD	COSMIC	16.704	Loss
AGC_PKC_PKCa_PRKCA_ST	Q8WZ42	TTN	P17252	PRKCA	S33158	E33156A	33156	Missense	proximal	-2	no	18.321	19.361	EPSD	COSMIC	16.704	Up-regulation
AGC_PKC_PKCa_PRKCA_ST	Q8WZ42	TTN	P17252	PRKCA	S33158	E33155K	33155	Missense	distal	-3	no	18.321	21.233	EPSD	COSMIC	16.704	Up-regulation
AGC_PKC_PKCa_PRKCA_ST	Q8WZ42	TTN	P17252	PRKCA	S33158	S33158N	33158	Missense	central	0	yes	18.321	0.000	EPSD	COSMIC	16.704	Loss
AGC_PKC_PKCa_PRKCA_ST	Q8WZ42	TTN	P17252	PRKCA	S33201	R33199Q	33199	Missense	proximal	-2	no	18.473	16.714	EPSD	COSMIC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	Q8WZ42	TTN	P17252	PRKCA	S33201	R33199W	33199	Missense	proximal	-2	no	18.473	16.475	EPSD	COSMIC	16.704	Loss
AGC_PKC_PKCa_PRKCA_ST	Q8WZ42	TTN	P17252	PRKCA	T33237	E33239K	33239	Missense	proximal	2	no	13.539	18.818	EPSD	COSMIC	16.704	Gain
AGC_PKC_PKCa_PRKCA_ST	Q8WZ42	TTN	P17252	PRKCA	S33251	S33250Y	33250	Missense	proximal	-1	no	17.482	17.033	EPSD	COSMIC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	Q8WZ42	TTN	P17252	PRKCA	S33251	S33245F	33245	Missense	distal	-6	no	17.482	17.397	EPSD	COSMIC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	Q8WZ42	TTN	P17252	PRKCA	S33251	P33248T	33248	Missense	distal	-3	no	17.482	17.167	EPSD	COSMIC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	Q8WZ42	TTN	P17252	PRKCA	S33251	S33245P	33245	Missense	distal	-6	no	17.482	17.450	EPSD	COSMIC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	Q8WZ42	TTN	P17252	PRKCA	S33251	S33247G	33247	Missense	distal	-4	no	17.482	17.573	EPSD	COSMIC	16.704	Up-regulation
AGC_PKC_PKCa_PRKCA_ST	Q8WZ42	TTN	P17252	PRKCA	S33400	T33397I	33397	Missense	distal	-3	no	17.797	17.473	EPSD	COSMIC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	Q8WZ42	TTN	P17252	PRKCA	S33400	E33405K	33405	Missense	distal	5	no	17.797	18.211	EPSD	COSMIC	16.704	Up-regulation
AGC_PKC_PKCa_PRKCA_ST	Q8WZ42	TTN	P17252	PRKCA	S33437	E33433Q	33433	Missense	distal	-4	no	17.345	17.663	EPSD	COSMIC	16.704	Up-regulation
AGC_PKC_PKCa_PRKCA_ST	Q8WZ42	TTN	P17252	PRKCA	T33478	E33475K	33475	Missense	distal	-3	no	15.180	18.092	EPSD	COSMIC	16.704	Gain
AGC_PKC_PKCa_PRKCA_ST	Q8WZ42	TTN	P17252	PRKCA	T33478	E33475Q	33475	Missense	distal	-3	no	15.180	17.261	EPSD	COSMIC;CCLE	16.704	Gain
AGC_PKC_PKCa_PRKCA_ST	Q8WZ42	TTN	P17252	PRKCA	T33498	E33501Q	33501	Missense	distal	3	no	17.246	16.031	EPSD	COSMIC	16.704	Loss
AGC_PKC_PKCa_PRKCA_ST	Q8WZ42	TTN	P17252	PRKCA	T33498	G33502S	33502	Missense	distal	4	no	17.246	17.603	EPSD	COSMIC	16.704	Up-regulation
AGC_PKC_PKCa_PRKCA_ST	Q8WZ42	TTN	P17252	PRKCA	T33498	P33494S	33494	Missense	distal	-4	no	17.246	17.417	EPSD	COSMIC	16.704	Up-regulation
AGC_PKC_PKCa_PRKCA_ST	Q8WZ42	TTN	P17252	PRKCA	S33531	V33527I	33527	Missense	distal	-4	no	17.815	17.845	EPSD	COSMIC	16.704	Up-regulation
AGC_PKC_PKCa_PRKCA_ST	Q8WZ42	TTN	P17252	PRKCA	S33531	G33525E	33525	Missense	distal	-6	no	17.815	17.848	EPSD	COSMIC	16.704	Up-regulation
AGC_PKC_PKCa_PRKCA_ST	Q8WZ42	TTN	P17252	PRKCA	S33608	K33613Q	33613	Missense	distal	5	no	17.326	17.173	EPSD	COSMIC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	Q8WZ42	TTN	P17252	PRKCA	S33608	V33606I	33606	Missense	proximal	-2	no	17.326	16.580	EPSD	COSMIC	16.704	Loss
AGC_PKC_PKCa_PRKCA_ST	Q8WZ42	TTN	P17252	PRKCA	S33916	E33918K	33918	Missense	proximal	2	no	13.527	18.806	EPSD	COSMIC	16.704	Gain
AGC_PKC_PKCa_PRKCA_ST	P49841	GSK3B	P17252	PRKCA	S2	S9F	9	Missense	distal	7	no	22.225	22.161	EPSD	COSMIC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	P49841	GSK3B	P17252	PRKCA	S2	S2P	2	Missense	central	0	yes	22.225	0.000	EPSD	COSMIC	16.704	Loss
AGC_PKC_PKCa_PRKCA_ST	P49841	GSK3B	P17252	PRKCA	T7	S9F	9	Missense	proximal	2	no	17.165	17.482	EPSD	COSMIC	16.704	Up-regulation
AGC_PKC_PKCa_PRKCA_ST	P49841	GSK3B	P17252	PRKCA	T7	S2P	2	Missense	distal	-5	no	17.165	17.490	EPSD	COSMIC	16.704	Up-regulation
AGC_PKC_PKCa_PRKCA_ST	P49841	GSK3B	P17252	PRKCA	T8	S9F	9	Missense	proximal	1	no	16.193	17.677	EPSD	COSMIC	16.704	Gain
AGC_PKC_PKCa_PRKCA_ST	P49841	GSK3B	P17252	PRKCA	S9	S9F	9	Missense	central	0	yes	20.161	0.000	PhosphoSitePlus	COSMIC	16.704	Loss
AGC_PKC_PKCa_PRKCA_ST	P49841	GSK3B	P17252	PRKCA	S9	P16A	16	Missense	distal	7	no	20.161	20.122	PhosphoSitePlus	COSMIC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	P49841	GSK3B	P17252	PRKCA	S9	S2P	2	Missense	distal	-7	no	20.161	20.158	PhosphoSitePlus	COSMIC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	P49841	GSK3B	P17252	PRKCA	S13	S9F	9	Missense	distal	-4	no	17.093	17.035	EPSD	COSMIC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	P49841	GSK3B	P17252	PRKCA	S13	P16A	16	Missense	distal	3	no	17.093	17.027	EPSD	COSMIC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	P49841	GSK3B	P17252	PRKCA	S21	S25C	25	Missense	distal	4	no	17.906	16.751	EPSD	COSMIC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	P49841	GSK3B	P17252	PRKCA	S21	P16A	16	Missense	distal	-5	no	17.906	17.528	EPSD	COSMIC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	P49841	GSK3B	P17252	PRKCA	S21	A22T	22	Missense	proximal	1	no	17.906	17.435	EPSD	COSMIC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	P49841	GSK3B	P17252	PRKCA	S25	D31Y	31	Missense	distal	6	no	17.924	17.961	EPSD	COSMIC	16.704	Up-regulation
AGC_PKC_PKCa_PRKCA_ST	P49841	GSK3B	P17252	PRKCA	S25	S25C	25	Missense	central	0	yes	17.924	0.000	EPSD	COSMIC	16.704	Loss
AGC_PKC_PKCa_PRKCA_ST	P49841	GSK3B	P17252	PRKCA	S25	A22T	22	Missense	distal	-3	no	17.924	18.210	EPSD	COSMIC	16.704	Up-regulation
AGC_PKC_PKCa_PRKCA_ST	P49841	GSK3B	P17252	PRKCA	S147	P154S	154	Missense	distal	7	no	17.546	17.509	EPSD	COSMIC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	P49841	GSK3B	P17252	PRKCA	S147	Y146C	146	Missense	proximal	-1	no	17.546	15.722	EPSD	COSMIC	16.704	Loss
AGC_PKC_PKCa_PRKCA_ST	P49841	GSK3B	P17252	PRKCA	S147	R148Q	148	Missense	proximal	1	no	17.546	17.429	EPSD	COSMIC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	P49841	GSK3B	P17252	PRKCA	S147	S147N	147	Missense	central	0	yes	17.546	0.000	EPSD	COSMIC	16.704	Loss
AGC_PKC_PKCa_PRKCA_ST	P49841	GSK3B	P17252	PRKCA	S147	Y140C	140	Missense	distal	-7	no	17.546	17.531	EPSD	COSMIC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	P49841	GSK3B	P17252	PRKCA	S147	A143G	143	Missense	distal	-4	no	17.546	17.550	EPSD	COSMIC	16.704	Up-regulation
AGC_PKC_PKCa_PRKCA_ST	P49841	GSK3B	P17252	PRKCA	S147	R141S	141	Missense	distal	-6	no	17.546	17.472	EPSD	COSMIC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	P35579	MYH9	P17252	PRKCA	S36	W33C	33	Missense	distal	-3	no	19.356	18.971	EPSD	COSMIC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	P35579	MYH9	P17252	PRKCA	S197	V194M	194	Missense	distal	-3	no	17.215	17.932	EPSD	COSMIC	16.704	Up-regulation
AGC_PKC_PKCa_PRKCA_ST	P35579	MYH9	P17252	PRKCA	S197	A195T	195	Missense	proximal	-2	no	17.215	17.406	EPSD	COSMIC	16.704	Up-regulation
AGC_PKC_PKCa_PRKCA_ST	P35579	MYH9	P17252	PRKCA	T638	P633L	633	Missense	distal	-5	no	16.837	16.810	EPSD	COSMIC;GDSC;CCLE	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	P35579	MYH9	P17252	PRKCA	T638	T638M	638	Missense	central	0	yes	16.837	0.000	EPSD	COSMIC	16.704	Loss
AGC_PKC_PKCa_PRKCA_ST	P35579	MYH9	P17252	PRKCA	T660	T664M	664	Missense	distal	4	no	16.435	16.916	EPSD	COSMIC	16.704	Gain
AGC_PKC_PKCa_PRKCA_ST	P35579	MYH9	P17252	PRKCA	S1122	S1126F	1126	Missense	distal	4	no	17.484	17.122	EPSD	COSMIC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	P35579	MYH9	P17252	PRKCA	S1122	L1116P	1116	Missense	distal	-6	no	17.484	17.517	EPSD	COSMIC	16.704	Up-regulation
AGC_PKC_PKCa_PRKCA_ST	P35579	MYH9	P17252	PRKCA	S1126	S1126F	1126	Missense	central	0	yes	17.515	0.000	EPSD	COSMIC	16.704	Loss
AGC_PKC_PKCa_PRKCA_ST	P35579	MYH9	P17252	PRKCA	S1126	A1130V	1130	Missense	distal	4	no	17.515	16.177	EPSD	COSMIC	16.704	Loss
AGC_PKC_PKCa_PRKCA_ST	P35579	MYH9	P17252	PRKCA	S1328	Q1323P	1323	Missense	distal	-5	no	18.263	18.314	EPSD	COSMIC	16.704	Up-regulation
AGC_PKC_PKCa_PRKCA_ST	P35579	MYH9	P17252	PRKCA	S1328	Q1323H	1323	Missense	distal	-5	no	18.263	18.060	EPSD	COSMIC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	P35579	MYH9	P17252	PRKCA	S1340	D1336N	1336	Missense	distal	-4	no	18.230	18.579	EPSD	COSMIC	16.704	Up-regulation
AGC_PKC_PKCa_PRKCA_ST	P35579	MYH9	P17252	PRKCA	S1340	S1340F	1340	Missense	central	0	yes	18.230	0.000	EPSD	COSMIC;GDSC;CCLE	16.704	Loss
AGC_PKC_PKCa_PRKCA_ST	P35579	MYH9	P17252	PRKCA	S1340	R1342Q	1342	Missense	proximal	2	no	18.230	14.396	EPSD	COSMIC;CCLE	16.704	Loss
AGC_PKC_PKCa_PRKCA_ST	P35579	MYH9	P17252	PRKCA	S1480	A1484V	1484	Missense	distal	4	no	17.106	15.768	EPSD	COSMIC	16.704	Loss
AGC_PKC_PKCa_PRKCA_ST	P35579	MYH9	P17252	PRKCA	S1480	A1484T	1484	Missense	distal	4	no	17.106	16.659	EPSD	COSMIC	16.704	Loss
AGC_PKC_PKCa_PRKCA_ST	P35579	MYH9	P17252	PRKCA	S1511	T1504A	1504	Missense	distal	-7	no	17.674	17.679	EPSD	COSMIC	16.704	Up-regulation
AGC_PKC_PKCa_PRKCA_ST	P35579	MYH9	P17252	PRKCA	S1511	L1509R	1509	Missense	proximal	-2	no	17.674	20.362	EPSD	COSMIC	16.704	Up-regulation
AGC_PKC_PKCa_PRKCA_ST	P35579	MYH9	P17252	PRKCA	S1526	R1528W	1528	Missense	proximal	2	no	17.059	11.620	EPSD	COSMIC	16.704	Loss
AGC_PKC_PKCa_PRKCA_ST	P35579	MYH9	P17252	PRKCA	S1606	R1605C	1605	Missense	proximal	-1	no	17.030	14.370	EPSD	COSMIC	16.704	Loss
AGC_PKC_PKCa_PRKCA_ST	P35579	MYH9	P17252	PRKCA	S1606	R1605H	1605	Missense	proximal	-1	no	17.030	16.707	EPSD	COSMIC;GDSC;CCLE	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	P35579	MYH9	P17252	PRKCA	S1677	K1676E	1676	Missense	proximal	-1	no	16.840	16.414	EPSD	COSMIC;GDSC	16.704	Loss
AGC_PKC_PKCa_PRKCA_ST	P35579	MYH9	P17252	PRKCA	S1677	K1674T	1674	Missense	distal	-3	no	16.840	14.703	EPSD	COSMIC	16.704	Loss
AGC_PKC_PKCa_PRKCA_ST	P35579	MYH9	P17252	PRKCA	S1677	M1678T	1678	Missense	proximal	1	no	16.840	16.555	EPSD	COSMIC	16.704	Loss
AGC_PKC_PKCa_PRKCA_ST	P35579	MYH9	P17252	PRKCA	S1714	G1715S	1715	Missense	proximal	1	no	17.204	16.983	EPSD	COSMIC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	P35579	MYH9	P17252	PRKCA	S1869	A1865V	1865	Missense	distal	-4	no	17.616	17.057	EPSD	COSMIC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	P35579	MYH9	P17252	PRKCA	S1869	D1863G	1863	Missense	distal	-6	no	17.616	17.666	EPSD	COSMIC	16.704	Up-regulation
AGC_PKC_PKCa_PRKCA_ST	P35579	MYH9	P17252	PRKCA	S1892	R1893C	1893	Missense	proximal	1	no	17.709	14.873	EPSD	COSMIC	16.704	Loss
AGC_PKC_PKCa_PRKCA_ST	P17812	CTPS1	P17252	PRKCA	S200	R202Q	202	Missense	proximal	2	no	19.253	15.419	EPSD	COSMIC	16.704	Loss
AGC_PKC_PKCa_PRKCA_ST	P17812	CTPS1	P17252	PRKCA	S200	Q198E	198	Missense	proximal	-2	no	19.253	16.886	EPSD	COSMIC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	P17812	CTPS1	P17252	PRKCA	S225	M232V	232	Missense	distal	7	no	17.845	17.778	EPSD	COSMIC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	P17812	CTPS1	P17252	PRKCA	S562	C559Y	559	Missense	distal	-3	no	20.243	18.422	EPSD	COSMIC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	P17812	CTPS1	P17252	PRKCA	S562	D565G	565	Missense	distal	3	no	20.243	21.328	EPSD	COSMIC	16.704	Up-regulation
AGC_PKC_PKCa_PRKCA_ST	P17812	CTPS1	P17252	PRKCA	S568	D565G	565	Missense	distal	-3	no	16.196	17.976	EPSD	COSMIC	16.704	Gain
AGC_PKC_PKCa_PRKCA_ST	Q16658	FSCN1	P17252	PRKCA	S187	F181L	181	Missense	distal	-6	no	17.746	17.766	EPSD	COSMIC	16.704	Up-regulation
AGC_PKC_PKCa_PRKCA_ST	O00168	FXYD1	P17252	PRKCA	S83	L87V	87	Missense	distal	4	no	20.721	20.192	EPSD	COSMIC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	O00168	FXYD1	P17252	PRKCA	S88	L87V	87	Missense	proximal	-1	no	22.299	21.256	PhosphoSitePlus	COSMIC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	O00168	FXYD1	P17252	PRKCA	T89	L87V	87	Missense	proximal	-2	no	18.283	18.129	EPSD	COSMIC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	Q15717	ELAVL1	P17252	PRKCA	S158	E159K	159	Missense	proximal	1	no	15.283	16.887	EPSD;PhosphoSitePlus	COSMIC	16.704	Gain
AGC_PKC_PKCa_PRKCA_ST	Q15717	ELAVL1	P17252	PRKCA	S202	R206W	206	Missense	distal	4	no	17.216	15.680	EPSD	COSMIC	16.704	Loss
AGC_PKC_PKCa_PRKCA_ST	Q15717	ELAVL1	P17252	PRKCA	S202	G208R	208	Missense	distal	6	no	17.216	17.366	EPSD	COSMIC	16.704	Up-regulation
AGC_PKC_PKCa_PRKCA_ST	Q15717	ELAVL1	P17252	PRKCA	S202	G208V	208	Missense	distal	6	no	17.216	17.205	EPSD	COSMIC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	Q15717	ELAVL1	P17252	PRKCA	S202	L195F	195	Missense	distal	-7	no	17.216	17.214	EPSD	COSMIC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	Q15717	ELAVL1	P17252	PRKCA	S221	V225I	225	Missense	distal	4	no	18.232	18.109	PhosphoSitePlus;EPSD	COSMIC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	P07355	ANXA2	P17252	PRKCA	S26	K28Q	28	Missense	proximal	2	no	17.978	14.565	PhosphoSitePlus;EPSD	COSMIC;CCLE	16.704	Loss
AGC_PKC_PKCa_PRKCA_ST	P07355	ANXA2	P17252	PRKCA	S117	G120E	120	Missense	distal	3	no	17.198	16.599	EPSD	COSMIC	16.704	Loss
AGC_PKC_PKCa_PRKCA_ST	P07355	ANXA2	P17252	PRKCA	S277	R273L	273	Missense	distal	-4	no	17.621	16.996	EPSD	COSMIC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	P07355	ANXA2	P17252	PRKCA	S277	T283M	283	Missense	distal	6	no	17.621	17.668	EPSD	COSMIC	16.704	Up-regulation
AGC_PKC_PKCa_PRKCA_ST	P07355	ANXA2	P17252	PRKCA	S277	R284L	284	Missense	distal	7	no	17.621	17.577	EPSD	COSMIC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	Q9UQ80	PA2G4	P17252	PRKCA	S2	G3S	3	Missense	proximal	1	no	17.394	17.174	EPSD	COSMIC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	Q9UQ80	PA2G4	P17252	PRKCA	S252	G256R	256	Missense	distal	4	no	17.758	18.362	EPSD	COSMIC	16.704	Up-regulation
AGC_PKC_PKCa_PRKCA_ST	Q9UQ80	PA2G4	P17252	PRKCA	T261	T261A	261	Missense	central	0	yes	18.343	0.000	EPSD	COSMIC	16.704	Loss
AGC_PKC_PKCa_PRKCA_ST	Q9UQ80	PA2G4	P17252	PRKCA	T261	G256R	256	Missense	distal	-5	no	18.343	18.633	EPSD	COSMIC	16.704	Up-regulation
AGC_PKC_PKCa_PRKCA_ST	P21359	NF1	P17252	PRKCA	S302	D301H	301	Missense	proximal	-1	no	18.764	19.323	EPSD	COSMIC	16.704	Up-regulation
AGC_PKC_PKCa_PRKCA_ST	P21359	NF1	P17252	PRKCA	S302	K297T	297	Missense	distal	-5	no	18.764	18.678	EPSD	COSMIC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	P21359	NF1	P17252	PRKCA	S302	G309A	309	Missense	distal	7	no	18.764	18.740	EPSD	COSMIC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	P21359	NF1	P17252	PRKCA	S302	A308V	308	Missense	distal	6	no	18.764	18.645	EPSD	COSMIC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	P21359	NF1	P17252	PRKCA	S302	S302N	302	Missense	central	0	yes	18.764	0.000	EPSD	COSMIC	16.704	Loss
AGC_PKC_PKCa_PRKCA_ST	P21359	NF1	P17252	PRKCA	S657	R652C	652	Missense	distal	-5	no	18.653	17.977	EPSD	COSMIC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	P21359	NF1	P17252	PRKCA	S657	R659W	659	Missense	proximal	2	no	18.653	13.213	EPSD	COSMIC	16.704	Loss
AGC_PKC_PKCa_PRKCA_ST	P21359	NF1	P17252	PRKCA	S657	R652H	652	Missense	distal	-5	no	18.653	18.298	EPSD	COSMIC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	P21359	NF1	P17252	PRKCA	S657	G663R	663	Missense	distal	6	no	18.653	18.802	EPSD	COSMIC	16.704	Up-regulation
AGC_PKC_PKCa_PRKCA_ST	P21359	NF1	P17252	PRKCA	S665	S666F	666	Missense	proximal	1	no	16.237	17.721	EPSD	COSMIC	16.704	Gain
AGC_PKC_PKCa_PRKCA_ST	P21359	NF1	P17252	PRKCA	S665	G663R	663	Missense	proximal	-2	no	16.237	19.109	EPSD	COSMIC	16.704	Gain
AGC_PKC_PKCa_PRKCA_ST	P21359	NF1	P17252	PRKCA	S666	G663R	663	Missense	distal	-3	no	13.752	17.013	EPSD	COSMIC	16.704	Gain
AGC_PKC_PKCa_PRKCA_ST	P21359	NF1	P17252	PRKCA	S858	A861P	861	Missense	distal	3	no	16.837	16.904	EPSD	COSMIC	16.704	Up-regulation
AGC_PKC_PKCa_PRKCA_ST	P21359	NF1	P17252	PRKCA	S858	P865T	865	Missense	distal	7	no	16.837	16.808	EPSD	COSMIC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	P21359	NF1	P17252	PRKCA	S871	I878T	878	Missense	distal	7	no	18.467	18.627	EPSD	COSMIC	16.704	Up-regulation
AGC_PKC_PKCa_PRKCA_ST	P21359	NF1	P17252	PRKCA	S871	E872K	872	Missense	proximal	1	no	18.467	20.071	EPSD	COSMIC	16.704	Up-regulation
AGC_PKC_PKCa_PRKCA_ST	P21359	NF1	P17252	PRKCA	S871	P865T	865	Missense	distal	-6	no	18.467	18.373	EPSD	COSMIC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	P21359	NF1	P17252	PRKCA	S876	I878T	878	Missense	proximal	2	no	18.150	18.371	EPSD	COSMIC	16.704	Up-regulation
AGC_PKC_PKCa_PRKCA_ST	P21359	NF1	P17252	PRKCA	S876	E872K	872	Missense	distal	-4	no	18.150	18.881	EPSD	COSMIC	16.704	Up-regulation
AGC_PKC_PKCa_PRKCA_ST	P21359	NF1	P17252	PRKCA	S1140	V1146I	1146	Missense	distal	6	no	23.101	23.156	EPSD	COSMIC	16.704	Up-regulation
AGC_PKC_PKCa_PRKCA_ST	P21359	NF1	P17252	PRKCA	S1140	L1147F	1147	Missense	distal	7	no	23.101	23.035	EPSD	COSMIC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	P21359	NF1	P17252	PRKCA	S2181	R2179C	2179	Missense	proximal	-2	no	24.251	22.551	EPSD	COSMIC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	P21359	NF1	P17252	PRKCA	S2181	S2181G	2181	Missense	central	0	yes	24.251	0.000	EPSD	COSMIC	16.704	Loss
AGC_PKC_PKCa_PRKCA_ST	P21359	NF1	P17252	PRKCA	S2186	E2193D	2193	Missense	distal	7	no	17.618	17.670	EPSD	COSMIC	16.704	Up-regulation
AGC_PKC_PKCa_PRKCA_ST	P21359	NF1	P17252	PRKCA	S2186	R2179C	2179	Missense	distal	-7	no	17.618	17.598	EPSD	COSMIC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	P21359	NF1	P17252	PRKCA	S2186	G2190S	2190	Missense	distal	4	no	17.618	17.975	EPSD	COSMIC	16.704	Up-regulation
AGC_PKC_PKCa_PRKCA_ST	P21359	NF1	P17252	PRKCA	S2186	S2181G	2181	Missense	distal	-5	no	17.618	17.754	EPSD	COSMIC	16.704	Up-regulation
AGC_PKC_PKCa_PRKCA_ST	P21359	NF1	P17252	PRKCA	S2186	S2191F	2191	Missense	distal	5	no	17.618	17.652	EPSD	COSMIC	16.704	Up-regulation
AGC_PKC_PKCa_PRKCA_ST	P21359	NF1	P17252	PRKCA	T2487	S2484F	2484	Missense	distal	-3	no	17.104	17.354	EPSD	COSMIC;GDSC;CCLE	16.704	Up-regulation
AGC_PKC_PKCa_PRKCA_ST	P21359	NF1	P17252	PRKCA	T2487	E2490K	2490	Missense	distal	3	no	17.104	17.720	EPSD	COSMIC	16.704	Up-regulation
AGC_PKC_PKCa_PRKCA_ST	P21359	NF1	P17252	PRKCA	T2487	W2494L	2494	Missense	distal	7	no	17.104	17.242	EPSD	COSMIC	16.704	Up-regulation
AGC_PKC_PKCa_PRKCA_ST	P21359	NF1	P17252	PRKCA	T2487	D2482V	2482	Missense	distal	-5	no	17.104	16.926	EPSD	COSMIC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	P21359	NF1	P17252	PRKCA	S2496	E2490K	2490	Missense	distal	-6	no	18.867	18.934	EPSD	COSMIC	16.704	Up-regulation
AGC_PKC_PKCa_PRKCA_ST	P21359	NF1	P17252	PRKCA	S2496	W2494L	2494	Missense	proximal	-2	no	18.867	18.176	EPSD	COSMIC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	P21359	NF1	P17252	PRKCA	S2496	S2500P	2500	Missense	distal	4	no	18.867	18.667	EPSD	COSMIC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	P21359	NF1	P17252	PRKCA	S2496	S2495F	2495	Missense	proximal	-1	no	18.867	18.159	EPSD	COSMIC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	P21359	NF1	P17252	PRKCA	S2496	Y2503C	2503	Missense	distal	7	no	18.867	18.696	EPSD	COSMIC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	P21359	NF1	P17252	PRKCA	S2515	V2511L	2511	Missense	distal	-4	no	19.017	19.058	EPSD	COSMIC	16.704	Up-regulation
AGC_PKC_PKCa_PRKCA_ST	P21359	NF1	P17252	PRKCA	S2515	G2512R	2512	Missense	distal	-3	no	19.017	22.278	EPSD	COSMIC	16.704	Up-regulation
AGC_PKC_PKCa_PRKCA_ST	P21359	NF1	P17252	PRKCA	S2515	T2514I	2514	Missense	proximal	-1	no	19.017	18.112	EPSD	COSMIC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	P21359	NF1	P17252	PRKCA	S2523	P2529H	2529	Missense	distal	6	no	17.566	17.527	EPSD	COSMIC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	P21359	NF1	P17252	PRKCA	S2523	S2530Y	2530	Missense	distal	7	no	17.566	17.560	EPSD	COSMIC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	P21359	NF1	P17252	PRKCA	S2523	S2523N	2523	Missense	central	0	yes	17.566	0.000	EPSD	COSMIC	16.704	Loss
AGC_PKC_PKCa_PRKCA_ST	P21359	NF1	P17252	PRKCA	T2540	L2547F	2547	Missense	distal	7	no	17.266	17.200	EPSD	COSMIC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	P21359	NF1	P17252	PRKCA	T2540	D2545H	2545	Missense	distal	5	no	17.266	17.369	EPSD	COSMIC	16.704	Up-regulation
AGC_PKC_PKCa_PRKCA_ST	P21359	NF1	P17252	PRKCA	T2540	T2540A	2540	Missense	central	0	yes	17.266	0.000	EPSD	COSMIC	16.704	Loss
AGC_PKC_PKCa_PRKCA_ST	P21359	NF1	P17252	PRKCA	T2540	D2545G	2545	Missense	distal	5	no	17.266	17.347	EPSD	COSMIC;GDSC;CCLE	16.704	Up-regulation
AGC_PKC_PKCa_PRKCA_ST	P21359	NF1	P17252	PRKCA	T2540	T2534S	2534	Missense	distal	-6	no	17.266	17.392	EPSD	COSMIC	16.704	Up-regulation
AGC_PKC_PKCa_PRKCA_ST	P21359	NF1	P17252	PRKCA	S2597	R2594C	2594	Missense	distal	-3	no	17.185	14.445	EPSD	COSMIC	16.704	Loss
AGC_PKC_PKCa_PRKCA_ST	P21359	NF1	P17252	PRKCA	S2597	R2594H	2594	Missense	distal	-3	no	17.185	13.329	EPSD	COSMIC	16.704	Loss
AGC_PKC_PKCa_PRKCA_ST	P21359	NF1	P17252	PRKCA	S2597	V2596F	2596	Missense	proximal	-1	no	17.185	17.940	EPSD	COSMIC	16.704	Up-regulation
AGC_PKC_PKCa_PRKCA_ST	P21359	NF1	P17252	PRKCA	S2597	R2594P	2594	Missense	distal	-3	no	17.185	13.336	EPSD	COSMIC	16.704	Loss
AGC_PKC_PKCa_PRKCA_ST	P21359	NF1	P17252	PRKCA	S2597	N2602I	2602	Missense	distal	5	no	17.185	17.212	EPSD	COSMIC	16.704	Up-regulation
AGC_PKC_PKCa_PRKCA_ST	P21359	NF1	P17252	PRKCA	S2597	E2600Q	2600	Missense	distal	3	no	17.185	15.970	EPSD	COSMIC;GDSC;CCLE	16.704	Loss
AGC_PKC_PKCa_PRKCA_ST	P21359	NF1	P17252	PRKCA	S2597	S2597L	2597	Missense	central	0	yes	17.185	0.000	EPSD	COSMIC	16.704	Loss
AGC_PKC_PKCa_PRKCA_ST	P21359	NF1	P17252	PRKCA	S2597	H2592R	2592	Missense	distal	-5	no	17.185	17.540	EPSD	COSMIC	16.704	Up-regulation
AGC_PKC_PKCa_PRKCA_ST	P21359	NF1	P17252	PRKCA	S2810	G2816A	2816	Missense	distal	6	no	20.229	20.336	EPSD	COSMIC	16.704	Up-regulation
AGC_PKC_PKCa_PRKCA_ST	P21359	NF1	P17252	PRKCA	S2810	S2810G	2810	Missense	central	0	yes	20.229	0.000	EPSD	COSMIC	16.704	Loss
AGC_PKC_PKCa_PRKCA_ST	P21359	NF1	P17252	PRKCA	S2810	T2805N	2805	Missense	distal	-5	no	20.229	19.972	EPSD	COSMIC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	P21359	NF1	P17252	PRKCA	S2810	C2808S	2808	Missense	proximal	-2	no	20.229	18.627	EPSD	COSMIC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	P21359	NF1	P17252	PRKCA	S2810	R2812Q	2812	Missense	proximal	2	no	20.229	16.395	EPSD	COSMIC	16.704	Loss
AGC_PKC_PKCa_PRKCA_ST	P21359	NF1	P17252	PRKCA	S2829	R2832H	2832	Missense	distal	3	no	18.144	17.431	EPSD	COSMIC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	P21359	NF1	P17252	PRKCA	S2829	A2827T	2827	Missense	proximal	-2	no	18.144	18.335	EPSD	COSMIC	16.704	Up-regulation
AGC_PKC_PKCa_PRKCA_ST	P21359	NF1	P17252	PRKCA	S2829	N2833D	2833	Missense	distal	4	no	18.144	18.501	EPSD	COSMIC	16.704	Up-regulation
AGC_PKC_PKCa_PRKCA_ST	P21359	NF1	P17252	PRKCA	S2829	N2833K	2833	Missense	distal	4	no	18.144	19.271	EPSD	COSMIC	16.704	Up-regulation
AGC_PKC_PKCa_PRKCA_ST	P21359	NF1	P17252	PRKCA	S2834	R2832H	2832	Missense	proximal	-2	no	21.932	17.379	EPSD	COSMIC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	P21359	NF1	P17252	PRKCA	S2834	A2827T	2827	Missense	distal	-7	no	21.932	21.927	EPSD	COSMIC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	P21359	NF1	P17252	PRKCA	S2834	K2837N	2837	Missense	distal	3	no	21.932	20.985	EPSD	COSMIC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	P21359	NF1	P17252	PRKCA	S2834	N2833D	2833	Missense	proximal	-1	no	21.932	21.594	EPSD	COSMIC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	P21359	NF1	P17252	PRKCA	S2834	N2833K	2833	Missense	proximal	-1	no	21.932	22.534	EPSD	COSMIC	16.704	Up-regulation
AGC_PKC_PKCa_PRKCA_ST	P30086	PEBP1	P17252	PRKCA	S60	K62R	62	Missense	proximal	2	no	17.037	17.458	EPSD	COSMIC	16.704	Up-regulation
AGC_PKC_PKCa_PRKCA_ST	P30086	PEBP1	P17252	PRKCA	S60	D59E	59	Missense	proximal	-1	no	17.037	17.550	EPSD	COSMIC	16.704	Up-regulation
AGC_PKC_PKCa_PRKCA_ST	P30086	PEBP1	P17252	PRKCA	S153	R155G	155	Missense	proximal	2	no	21.727	16.482	PhosphoSitePlus	COSMIC	16.704	Loss
AGC_PKC_PKCa_PRKCA_ST	Q05193	DNM1	P17252	PRKCA	S264	R266C	266	Missense	proximal	2	no	18.801	14.451	EPSD	COSMIC	16.704	Loss
AGC_PKC_PKCa_PRKCA_ST	Q05193	DNM1	P17252	PRKCA	S264	S261Y	261	Missense	distal	-3	no	18.801	17.111	EPSD	COSMIC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	Q05193	DNM1	P17252	PRKCA	S264	P263L	263	Missense	proximal	-1	no	18.801	18.681	EPSD	COSMIC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	Q05193	DNM1	P17252	PRKCA	S264	R271C	271	Missense	distal	7	no	18.801	18.578	EPSD	COSMIC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	Q05193	DNM1	P17252	PRKCA	S389	I392M	392	Missense	distal	3	no	16.376	17.657	EPSD	COSMIC;CCLE	16.704	Gain
AGC_PKC_PKCa_PRKCA_ST	Q05193	DNM1	P17252	PRKCA	S619	S619P	619	Missense	central	0	yes	19.028	0.000	EPSD	COSMIC	16.704	Loss
AGC_PKC_PKCa_PRKCA_ST	Q05193	DNM1	P17252	PRKCA	S619	A618V	618	Missense	proximal	-1	no	19.028	18.124	EPSD	COSMIC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	Q05193	DNM1	P17252	PRKCA	S619	S615F	615	Missense	distal	-4	no	19.028	18.970	EPSD	COSMIC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	Q05193	DNM1	P17252	PRKCA	S619	S615P	615	Missense	distal	-4	no	19.028	18.857	EPSD	COSMIC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	Q05193	DNM1	P17252	PRKCA	T684	M686R	686	Missense	proximal	2	no	13.675	18.123	EPSD	COSMIC	16.704	Gain
AGC_PKC_PKCa_PRKCA_ST	Q05193	DNM1	P17252	PRKCA	S857	R859S	859	Missense	proximal	2	no	20.368	15.748	EPSD	COSMIC	16.704	Loss
AGC_PKC_PKCa_PRKCA_ST	Q05193	DNM1	P17252	PRKCA	S857	P855Q	855	Missense	proximal	-2	no	20.368	21.651	EPSD	COSMIC	16.704	Up-regulation
AGC_PKC_PKCa_PRKCA_ST	P04049	RAF1	P17252	PRKCA	S43	G46D	46	Missense	distal	3	no	19.600	18.514	EPSD;PhosphoSitePlus	COSMIC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	P04049	RAF1	P17252	PRKCA	S43	R41P	41	Missense	proximal	-2	no	19.600	16.557	EPSD;PhosphoSitePlus	COSMIC	16.704	Loss
AGC_PKC_PKCa_PRKCA_ST	P04049	RAF1	P17252	PRKCA	S43	L48F	48	Missense	distal	5	no	19.600	19.824	EPSD;PhosphoSitePlus	COSMIC	16.704	Up-regulation
AGC_PKC_PKCa_PRKCA_ST	P04049	RAF1	P17252	PRKCA	S43	A42E	42	Missense	proximal	-1	no	19.600	20.177	EPSD;PhosphoSitePlus	COSMIC	16.704	Up-regulation
AGC_PKC_PKCa_PRKCA_ST	P04049	RAF1	P17252	PRKCA	T213	L209P	209	Missense	distal	-4	no	17.244	17.504	EPSD	COSMIC	16.704	Up-regulation
AGC_PKC_PKCa_PRKCA_ST	P04049	RAF1	P17252	PRKCA	T213	A208T	208	Missense	distal	-5	no	17.244	17.625	EPSD	COSMIC	16.704	Up-regulation
AGC_PKC_PKCa_PRKCA_ST	P04049	RAF1	P17252	PRKCA	T213	M217I	217	Missense	distal	4	no	17.244	15.749	EPSD	COSMIC	16.704	Loss
AGC_PKC_PKCa_PRKCA_ST	P04049	RAF1	P17252	PRKCA	S220	M217I	217	Missense	distal	-3	no	19.272	17.757	EPSD	COSMIC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	P04049	RAF1	P17252	PRKCA	S252	S259A	259	Missense	distal	7	no	17.092	17.090	EPSD	COSMIC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	P04049	RAF1	P17252	PRKCA	S252	S259C	259	Missense	distal	7	no	17.092	16.915	EPSD	COSMIC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	P04049	RAF1	P17252	PRKCA	S252	S259P	259	Missense	distal	7	no	17.092	17.128	EPSD	COSMIC	16.704	Up-regulation
AGC_PKC_PKCa_PRKCA_ST	P04049	RAF1	P17252	PRKCA	S252	L251V	251	Missense	proximal	-1	no	17.092	16.049	EPSD	COSMIC	16.704	Loss
AGC_PKC_PKCa_PRKCA_ST	P04049	RAF1	P17252	PRKCA	S257	S259A	259	Missense	proximal	2	no	18.677	18.598	EPSD	COSMIC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	P04049	RAF1	P17252	PRKCA	S257	P261L	261	Missense	distal	4	no	18.677	18.084	EPSD	COSMIC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	P04049	RAF1	P17252	PRKCA	S257	S259C	259	Missense	proximal	2	no	18.677	18.946	EPSD	COSMIC	16.704	Up-regulation
AGC_PKC_PKCa_PRKCA_ST	P04049	RAF1	P17252	PRKCA	S257	S259P	259	Missense	proximal	2	no	18.677	18.094	EPSD	COSMIC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	P04049	RAF1	P17252	PRKCA	S257	T260K	260	Missense	distal	3	no	18.677	19.891	EPSD	COSMIC	16.704	Up-regulation
AGC_PKC_PKCa_PRKCA_ST	P04049	RAF1	P17252	PRKCA	S257	P261T	261	Missense	distal	4	no	18.677	18.446	EPSD	COSMIC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	P04049	RAF1	P17252	PRKCA	S257	N262K	262	Missense	distal	5	no	18.677	19.183	EPSD	COSMIC	16.704	Up-regulation
AGC_PKC_PKCa_PRKCA_ST	P04049	RAF1	P17252	PRKCA	S257	T260I	260	Missense	distal	3	no	18.677	17.964	EPSD	COSMIC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	P04049	RAF1	P17252	PRKCA	S257	L251V	251	Missense	distal	-6	no	18.677	18.628	EPSD	COSMIC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	P04049	RAF1	P17252	PRKCA	S257	P261S	261	Missense	distal	4	no	18.677	18.876	EPSD	COSMIC	16.704	Up-regulation
AGC_PKC_PKCa_PRKCA_ST	P04049	RAF1	P17252	PRKCA	S257	V263A	263	Missense	distal	6	no	18.677	18.795	EPSD	COSMIC	16.704	Up-regulation
AGC_PKC_PKCa_PRKCA_ST	P04049	RAF1	P17252	PRKCA	S257	V263D	263	Missense	distal	6	no	18.677	18.748	EPSD	COSMIC	16.704	Up-regulation
AGC_PKC_PKCa_PRKCA_ST	P04049	RAF1	P17252	PRKCA	T258	T260K	260	Missense	proximal	2	no	13.602	17.991	EPSD	COSMIC	16.704	Gain
AGC_PKC_PKCa_PRKCA_ST	P04049	RAF1	P17252	PRKCA	S352	S359C	359	Missense	distal	7	no	16.787	16.610	EPSD	COSMIC	16.704	Loss
AGC_PKC_PKCa_PRKCA_ST	P04049	RAF1	P17252	PRKCA	S359	G361R	361	Missense	proximal	2	no	12.950	18.195	EPSD	COSMIC	16.704	Gain
AGC_PKC_PKCa_PRKCA_ST	P23975	SLC6A2	P17252	PRKCA	T258	G260R	260	Missense	proximal	2	no	12.312	17.557	PhosphoSitePlus;EPSD	COSMIC	16.704	Gain
AGC_PKC_PKCa_PRKCA_ST	P23975	SLC6A2	P17252	PRKCA	S259	G260E	260	Missense	proximal	1	no	17.416	16.803	EPSD;PhosphoSitePlus	COSMIC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	P23975	SLC6A2	P17252	PRKCA	S259	G255R	255	Missense	distal	-4	no	17.416	17.518	EPSD;PhosphoSitePlus	COSMIC;CCLE	16.704	Up-regulation
AGC_PKC_PKCa_PRKCA_ST	P23975	SLC6A2	P17252	PRKCA	S259	S259L	259	Missense	central	0	yes	17.416	0.000	EPSD;PhosphoSitePlus	COSMIC	16.704	Loss
AGC_PKC_PKCa_PRKCA_ST	P23975	SLC6A2	P17252	PRKCA	S259	G260R	260	Missense	proximal	1	no	17.416	18.369	EPSD;PhosphoSitePlus	COSMIC	16.704	Up-regulation
AGC_PKC_PKCa_PRKCA_ST	P23975	SLC6A2	P17252	PRKCA	S259	G255W	255	Missense	distal	-4	no	17.416	16.692	EPSD;PhosphoSitePlus	COSMIC;GDSC;CCLE	16.704	Loss
AGC_PKC_PKCa_PRKCA_ST	P23975	SLC6A2	P17252	PRKCA	S259	W253C	253	Missense	distal	-6	no	17.416	17.331	EPSD;PhosphoSitePlus	COSMIC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	O94806	PRKD3	P17252	PRKCA	S13	A18P	18	Missense	distal	5	no	17.886	17.942	EPSD	COSMIC	16.704	Up-regulation
AGC_PKC_PKCa_PRKCA_ST	O94806	PRKD3	P17252	PRKCA	S31	G35K	35	Missense	distal	4	no	18.670	19.445	EPSD	COSMIC	16.704	Up-regulation
AGC_PKC_PKCa_PRKCA_ST	O94806	PRKD3	P17252	PRKCA	S37	R39Q	39	Missense	proximal	2	no	18.465	14.631	EPSD	COSMIC	16.704	Loss
AGC_PKC_PKCa_PRKCA_ST	O94806	PRKD3	P17252	PRKCA	S37	G35K	35	Missense	proximal	-2	no	18.465	19.709	EPSD	COSMIC	16.704	Up-regulation
AGC_PKC_PKCa_PRKCA_ST	O94806	PRKD3	P17252	PRKCA	S213	R211C	211	Missense	proximal	-2	no	20.336	18.636	EPSD	COSMIC;GDSC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	O94806	PRKD3	P17252	PRKCA	S247	S240L	240	Missense	distal	-7	no	17.954	17.948	EPSD	COSMIC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	O94806	PRKD3	P17252	PRKCA	S315	V317I	317	Missense	proximal	2	no	20.306	20.288	EPSD	COSMIC;GDSC;CCLE	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	O94806	PRKD3	P17252	PRKCA	S315	H310R	310	Missense	distal	-5	no	20.306	20.662	EPSD	COSMIC	16.704	Up-regulation
AGC_PKC_PKCa_PRKCA_ST	O94806	PRKD3	P17252	PRKCA	S406	R402M	402	Missense	distal	-4	no	21.892	21.971	EPSD	COSMIC	16.704	Up-regulation
AGC_PKC_PKCa_PRKCA_ST	O94806	PRKD3	P17252	PRKCA	S415	S414I	414	Missense	proximal	-1	no	18.899	17.616	EPSD	COSMIC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	O94806	PRKD3	P17252	PRKCA	S415	E420D	420	Missense	distal	5	no	18.899	18.807	EPSD	COSMIC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	O94806	PRKD3	P17252	PRKCA	S731	K730T	730	Missense	proximal	-1	no	20.461	19.638	PhosphoSitePlus	COSMIC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	O94806	PRKD3	P17252	PRKCA	S735	K730T	730	Missense	distal	-5	no	20.009	19.923	EPSD	COSMIC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	P10275	AR	P17252	PRKCA	S16	A22T	22	Missense	distal	6	no	18.915	18.837	EPSD	COSMIC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	P10275	AR	P17252	PRKCA	S16	F23L	23	Missense	distal	7	no	18.915	18.982	EPSD	COSMIC	16.704	Up-regulation
AGC_PKC_PKCa_PRKCA_ST	P10275	AR	P17252	PRKCA	S16	R13W	13	Missense	distal	-3	no	18.915	16.561	EPSD	COSMIC	16.704	Loss
AGC_PKC_PKCa_PRKCA_ST	P10275	AR	P17252	PRKCA	S16	G21A	21	Missense	distal	5	no	18.915	19.158	EPSD	COSMIC	16.704	Up-regulation
AGC_PKC_PKCa_PRKCA_ST	P10275	AR	P17252	PRKCA	S16	P12A	12	Missense	distal	-4	no	18.915	19.174	EPSD	COSMIC	16.704	Up-regulation
AGC_PKC_PKCa_PRKCA_ST	P10275	AR	P17252	PRKCA	T18	A22T	22	Missense	distal	4	no	19.880	19.433	EPSD	COSMIC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	P10275	AR	P17252	PRKCA	T18	F23L	23	Missense	distal	5	no	19.880	19.656	EPSD	COSMIC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	P10275	AR	P17252	PRKCA	T18	Q24H	24	Missense	distal	6	no	19.880	19.925	EPSD	COSMIC	16.704	Up-regulation
AGC_PKC_PKCa_PRKCA_ST	P10275	AR	P17252	PRKCA	T18	R13W	13	Missense	distal	-5	no	19.880	19.566	EPSD	COSMIC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	P10275	AR	P17252	PRKCA	T18	G21A	21	Missense	distal	3	no	19.880	18.922	EPSD	COSMIC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	P10275	AR	P17252	PRKCA	T18	P12A	12	Missense	distal	-6	no	19.880	19.875	EPSD	COSMIC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	P10275	AR	P17252	PRKCA	S29	A22T	22	Missense	distal	-7	no	16.872	16.867	EPSD	COSMIC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	P10275	AR	P17252	PRKCA	S29	F23L	23	Missense	distal	-6	no	16.872	16.892	EPSD	COSMIC	16.704	Up-regulation
AGC_PKC_PKCa_PRKCA_ST	P10275	AR	P17252	PRKCA	S29	V30M	30	Missense	proximal	1	no	16.872	16.532	EPSD	COSMIC	16.704	Loss
AGC_PKC_PKCa_PRKCA_ST	P10275	AR	P17252	PRKCA	S29	Q24H	24	Missense	distal	-5	no	16.872	16.668	EPSD	COSMIC	16.704	Loss
AGC_PKC_PKCa_PRKCA_ST	P10275	AR	P17252	PRKCA	S83	Q79E	79	Missense	distal	-4	no	17.057	16.738	EPSD	COSMIC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	P10275	AR	P17252	PRKCA	S83	Q86K	86	Missense	distal	3	no	17.057	18.888	EPSD	COSMIC	16.704	Up-regulation
AGC_PKC_PKCa_PRKCA_ST	P10275	AR	P17252	PRKCA	S83	E81Q	81	Missense	proximal	-2	no	17.057	19.424	EPSD	COSMIC	16.704	Up-regulation
AGC_PKC_PKCa_PRKCA_ST	P10275	AR	P17252	PRKCA	S83	Q90H	90	Missense	distal	7	no	17.057	16.990	EPSD	COSMIC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	P10275	AR	P17252	PRKCA	S83	Q79R	79	Missense	distal	-4	no	17.057	17.434	EPSD	COSMIC	16.704	Up-regulation
AGC_PKC_PKCa_PRKCA_ST	P10275	AR	P17252	PRKCA	S83	P84H	84	Missense	proximal	1	no	17.057	17.018	EPSD	COSMIC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	P10275	AR	P17252	PRKCA	S208	S215L	215	Missense	distal	7	no	18.352	18.355	EPSD	COSMIC	16.704	Up-regulation
AGC_PKC_PKCa_PRKCA_ST	P10275	AR	P17252	PRKCA	S208	A214V	214	Missense	distal	6	no	18.352	18.234	EPSD	COSMIC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	P10275	AR	P17252	PRKCA	S244	K241R	241	Missense	distal	-3	no	14.892	16.918	EPSD	COSMIC	16.704	Gain
AGC_PKC_PKCa_PRKCA_ST	P10275	AR	P17252	PRKCA	S302	E304K	304	Missense	proximal	2	no	11.426	16.706	EPSD	COSMIC	16.704	Gain
AGC_PKC_PKCa_PRKCA_ST	P10275	AR	P17252	PRKCA	S424	G421R	421	Missense	distal	-3	no	15.291	18.553	EPSD	COSMIC	16.704	Gain
AGC_PKC_PKCa_PRKCA_ST	P10275	AR	P17252	PRKCA	S426	S424C	424	Missense	proximal	-2	no	16.207	17.809	EPSD	COSMIC	16.704	Gain
AGC_PKC_PKCa_PRKCA_ST	P10275	AR	P17252	PRKCA	S579	T576A	576	Missense	distal	-3	no	17.121	16.835	PhosphoSitePlus	COSMIC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	P10275	AR	P17252	PRKCA	S579	C580R	580	Missense	proximal	1	no	17.121	19.957	PhosphoSitePlus	COSMIC	16.704	Up-regulation
AGC_PKC_PKCa_PRKCA_ST	P10275	AR	P17252	PRKCA	S579	L575I	575	Missense	distal	-4	no	17.121	17.110	PhosphoSitePlus	COSMIC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	P10275	AR	P17252	PRKCA	S579	K581R	581	Missense	proximal	2	no	17.121	17.542	PhosphoSitePlus	COSMIC	16.704	Up-regulation
AGC_PKC_PKCa_PRKCA_ST	P10275	AR	P17252	PRKCA	S579	F584L	584	Missense	distal	5	no	17.121	16.896	PhosphoSitePlus	COSMIC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	P10275	AR	P17252	PRKCA	S651	S648R	648	Missense	distal	-3	no	15.043	17.912	EPSD	COSMIC	16.704	Gain
AGC_PKC_PKCa_PRKCA_ST	P10275	AR	P17252	PRKCA	S792	H790Q	790	Missense	proximal	-2	no	14.877	17.671	EPSD	COSMIC	16.704	Gain
AGC_PKC_PKCa_PRKCA_ST	P10415	BCL2	P17252	PRKCA	S24	G27D	27	Missense	distal	3	no	20.144	19.058	EPSD	COSMIC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	P10415	BCL2	P17252	PRKCA	S24	Y18F	18	Missense	distal	-6	no	20.144	20.112	EPSD	COSMIC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	P10415	BCL2	P17252	PRKCA	S24	W30C	30	Missense	distal	6	no	20.144	20.152	EPSD	COSMIC	16.704	Up-regulation
AGC_PKC_PKCa_PRKCA_ST	P10415	BCL2	P17252	PRKCA	S24	K17N	17	Missense	distal	-7	no	20.144	20.139	EPSD	COSMIC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	P10415	BCL2	P17252	PRKCA	S24	Y28F	28	Missense	distal	4	no	20.144	20.180	EPSD	COSMIC	16.704	Up-regulation
AGC_PKC_PKCa_PRKCA_ST	P10415	BCL2	P17252	PRKCA	S24	Y21H	21	Missense	distal	-3	no	20.144	20.848	EPSD	COSMIC	16.704	Up-regulation
AGC_PKC_PKCa_PRKCA_ST	P10415	BCL2	P17252	PRKCA	S24	D31A	31	Missense	distal	7	no	20.144	20.139	EPSD	COSMIC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	P10415	BCL2	P17252	PRKCA	S24	K17E	17	Missense	distal	-7	no	20.144	20.136	EPSD	COSMIC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	P10415	BCL2	P17252	PRKCA	S24	E29Q	29	Missense	distal	5	no	20.144	20.405	EPSD	COSMIC	16.704	Up-regulation
AGC_PKC_PKCa_PRKCA_ST	P10415	BCL2	P17252	PRKCA	S24	Y21C	21	Missense	distal	-3	no	20.144	21.964	EPSD	COSMIC	16.704	Up-regulation
AGC_PKC_PKCa_PRKCA_ST	P10415	BCL2	P17252	PRKCA	S24	R26K	26	Missense	proximal	2	no	20.144	19.722	EPSD	COSMIC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	P00749	PLAU	P17252	PRKCA	S158	P160S	160	Missense	proximal	2	no	16.408	16.991	PhosphoSitePlus;EPSD	COSMIC;GDSC;CCLE	16.704	Gain
AGC_PKC_PKCa_PRKCA_ST	P00749	PLAU	P17252	PRKCA	S158	S159F	159	Missense	proximal	1	no	16.408	17.892	PhosphoSitePlus;EPSD	COSMIC	16.704	Gain
AGC_PKC_PKCa_PRKCA_ST	P00749	PLAU	P17252	PRKCA	S341	P348S	348	Missense	distal	7	no	18.203	18.167	EPSD	COSMIC;GDSC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	P00749	PLAU	P17252	PRKCA	S341	H342P	342	Missense	proximal	1	no	18.203	18.242	EPSD	COSMIC	16.704	Up-regulation
AGC_PKC_PKCa_PRKCA_ST	P00749	PLAU	P17252	PRKCA	S341	I340M	340	Missense	proximal	-1	no	18.203	20.146	EPSD	COSMIC	16.704	Up-regulation
AGC_PKC_PKCa_PRKCA_ST	P13569	CFTR	P17252	PRKCA	S4	V11I	11	Missense	distal	7	no	17.326	17.229	EPSD	COSMIC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	P13569	CFTR	P17252	PRKCA	S4	S4L	4	Missense	central	0	yes	17.326	0.000	EPSD	COSMIC;GDSC	16.704	Loss
AGC_PKC_PKCa_PRKCA_ST	P13569	CFTR	P17252	PRKCA	T501	E504K	504	Missense	distal	3	no	18.338	18.954	EPSD	COSMIC	16.704	Up-regulation
AGC_PKC_PKCa_PRKCA_ST	P13569	CFTR	P17252	PRKCA	T501	W496L	496	Missense	distal	-5	no	18.338	18.524	EPSD	COSMIC	16.704	Up-regulation
AGC_PKC_PKCa_PRKCA_ST	P13569	CFTR	P17252	PRKCA	S660	R658K	658	Missense	proximal	-2	no	19.706	18.078	EPSD;PhosphoSitePlus	COSMIC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	P13569	CFTR	P17252	PRKCA	S660	S660L	660	Missense	central	0	yes	19.706	0.000	EPSD;PhosphoSitePlus	COSMIC	16.704	Loss
AGC_PKC_PKCa_PRKCA_ST	P13569	CFTR	P17252	PRKCA	S660	T665N	665	Missense	distal	5	no	19.706	19.660	EPSD;PhosphoSitePlus	COSMIC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	P13569	CFTR	P17252	PRKCA	S660	H667R	667	Missense	distal	7	no	19.706	19.777	EPSD;PhosphoSitePlus	COSMIC	16.704	Up-regulation
AGC_PKC_PKCa_PRKCA_ST	P13569	CFTR	P17252	PRKCA	S660	A655T	655	Missense	distal	-5	no	19.706	20.086	EPSD;PhosphoSitePlus	COSMIC	16.704	Up-regulation
AGC_PKC_PKCa_PRKCA_ST	P13569	CFTR	P17252	PRKCA	S670	H667R	667	Missense	distal	-3	no	16.686	20.542	EPSD	COSMIC	16.704	Gain
AGC_PKC_PKCa_PRKCA_ST	P13569	CFTR	P17252	PRKCA	T682	Q685K	685	Missense	distal	3	no	15.755	17.585	EPSD	COSMIC	16.704	Gain
AGC_PKC_PKCa_PRKCA_ST	P13569	CFTR	P17252	PRKCA	S686	E681Q	681	Missense	distal	-5	no	19.152	19.307	EPSD	COSMIC	16.704	Up-regulation
AGC_PKC_PKCa_PRKCA_ST	P13569	CFTR	P17252	PRKCA	S686	Q685K	685	Missense	proximal	-1	no	19.152	20.027	EPSD	COSMIC	16.704	Up-regulation
AGC_PKC_PKCa_PRKCA_ST	P13569	CFTR	P17252	PRKCA	S700	L702I	702	Missense	proximal	2	no	18.593	18.548	EPSD	COSMIC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	P13569	CFTR	P17252	PRKCA	S700	G694R	694	Missense	distal	-6	no	18.593	18.700	EPSD	COSMIC	16.704	Up-regulation
AGC_PKC_PKCa_PRKCA_ST	P13569	CFTR	P17252	PRKCA	S700	K696I	696	Missense	distal	-4	no	18.593	17.922	EPSD	COSMIC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	P13569	CFTR	P17252	PRKCA	S700	S700F	700	Missense	central	0	yes	18.593	0.000	EPSD	COSMIC	16.704	Loss
AGC_PKC_PKCa_PRKCA_ST	P13569	CFTR	P17252	PRKCA	S700	S700Y	700	Missense	central	0	yes	18.593	0.000	EPSD	COSMIC	16.704	Loss
AGC_PKC_PKCa_PRKCA_ST	P13569	CFTR	P17252	PRKCA	S700	K698E	698	Missense	proximal	-2	no	18.593	16.094	EPSD	COSMIC	16.704	Loss
AGC_PKC_PKCa_PRKCA_ST	P13569	CFTR	P17252	PRKCA	S700	K698N	698	Missense	proximal	-2	no	18.593	17.024	EPSD	COSMIC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	P13569	CFTR	P17252	PRKCA	S700	G694E	694	Missense	distal	-6	no	18.593	18.626	EPSD	COSMIC	16.704	Up-regulation
AGC_PKC_PKCa_PRKCA_ST	P13569	CFTR	P17252	PRKCA	S707	L702I	702	Missense	distal	-5	no	19.036	18.592	EPSD	COSMIC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	P13569	CFTR	P17252	PRKCA	S707	S700F	700	Missense	distal	-7	no	19.036	19.028	EPSD	COSMIC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	P13569	CFTR	P17252	PRKCA	S737	E743K	743	Missense	distal	6	no	20.116	20.210	PhosphoSitePlus;EPSD	COSMIC	16.704	Up-regulation
AGC_PKC_PKCa_PRKCA_ST	P13569	CFTR	P17252	PRKCA	S768	R765M	765	Missense	distal	-3	no	19.597	16.625	EPSD	COSMIC	16.704	Loss
AGC_PKC_PKCa_PRKCA_ST	P13569	CFTR	P17252	PRKCA	S768	H775Y	775	Missense	distal	7	no	19.597	19.616	EPSD	COSMIC	16.704	Up-regulation
AGC_PKC_PKCa_PRKCA_ST	P13569	CFTR	P17252	PRKCA	S790	H784R	784	Missense	distal	-6	no	18.923	18.990	EPSD	COSMIC	16.704	Up-regulation
AGC_PKC_PKCa_PRKCA_ST	P13569	CFTR	P17252	PRKCA	S790	T788K	788	Missense	proximal	-2	no	18.923	20.189	EPSD	COSMIC	16.704	Up-regulation
AGC_PKC_PKCa_PRKCA_ST	P13569	CFTR	P17252	PRKCA	S813	L812F	812	Missense	proximal	-1	no	18.100	17.812	EPSD;PhosphoSitePlus	COSMIC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	P13569	CFTR	P17252	PRKCA	S813	R810E	810	Missense	distal	-3	no	18.100	13.162	EPSD;PhosphoSitePlus	COSMIC	16.704	Loss
AGC_PKC_PKCa_PRKCA_ST	P13569	CFTR	P17252	PRKCA	S813	E819K	819	Missense	distal	6	no	18.100	18.194	EPSD;PhosphoSitePlus	COSMIC	16.704	Up-regulation
AGC_PKC_PKCa_PRKCA_ST	P13569	CFTR	P17252	PRKCA	S1248	S1248L	1248	Missense	central	0	yes	21.308	0.000	EPSD	COSMIC	16.704	Loss
AGC_PKC_PKCa_PRKCA_ST	P13569	CFTR	P17252	PRKCA	S1426	K1429R	1429	Missense	distal	3	no	16.529	17.152	EPSD	COSMIC	16.704	Gain
AGC_PKC_PKCa_PRKCA_ST	P13569	CFTR	P17252	PRKCA	S1455	K1461N	1461	Missense	distal	6	no	17.317	17.155	EPSD	COSMIC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	P13569	CFTR	P17252	PRKCA	S1455	P1451L	1451	Missense	distal	-4	no	17.317	17.057	EPSD	COSMIC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	P13569	CFTR	P17252	PRKCA	S1456	K1461N	1461	Missense	distal	5	no	17.642	17.136	EPSD	COSMIC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	P13569	CFTR	P17252	PRKCA	S1456	P1451L	1451	Missense	distal	-5	no	17.642	17.616	EPSD	COSMIC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	Q15172	PPP2R5A	P17252	PRKCA	S2	S2L	2	Missense	central	0	yes	17.465	0.000	EPSD	COSMIC	16.704	Loss
AGC_PKC_PKCa_PRKCA_ST	Q15172	PPP2R5A	P17252	PRKCA	S38	Q43E	43	Missense	distal	5	no	18.411	18.149	EPSD	COSMIC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	Q15172	PPP2R5A	P17252	PRKCA	S38	Q39E	39	Missense	proximal	1	no	18.411	16.961	EPSD	COSMIC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	Q15172	PPP2R5A	P17252	PRKCA	S41	Q43E	43	Missense	proximal	2	no	17.700	15.833	PhosphoSitePlus	COSMIC	16.704	Loss
AGC_PKC_PKCa_PRKCA_ST	Q15172	PPP2R5A	P17252	PRKCA	S41	Q39E	39	Missense	proximal	-2	no	17.700	15.332	PhosphoSitePlus	COSMIC	16.704	Loss
AGC_PKC_PKCa_PRKCA_ST	Q15172	PPP2R5A	P17252	PRKCA	S42	Q43E	43	Missense	proximal	1	no	16.842	15.392	EPSD	COSMIC	16.704	Loss
AGC_PKC_PKCa_PRKCA_ST	Q15172	PPP2R5A	P17252	PRKCA	S42	Q39E	39	Missense	distal	-3	no	16.842	14.761	EPSD	COSMIC	16.704	Loss
AGC_PKC_PKCa_PRKCA_ST	Q15172	PPP2R5A	P17252	PRKCA	T281	L285F	285	Missense	distal	4	no	17.530	17.961	EPSD	COSMIC	16.704	Up-regulation
AGC_PKC_PKCa_PRKCA_ST	Q9Y624	F11R	P17252	PRKCA	S57	F55L	55	Missense	proximal	-2	no	16.213	17.498	EPSD	COSMIC	16.704	Gain
AGC_PKC_PKCa_PRKCA_ST	Q9Y624	F11R	P17252	PRKCA	S274	S275L	275	Missense	proximal	1	no	18.112	18.938	EPSD	COSMIC	16.704	Up-regulation
AGC_PKC_PKCa_PRKCA_ST	Q9Y624	F11R	P17252	PRKCA	S274	T273A	273	Missense	proximal	-1	no	18.112	17.931	EPSD	COSMIC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	Q9Y624	F11R	P17252	PRKCA	S274	D267H	267	Missense	distal	-7	no	18.112	18.114	EPSD	COSMIC	16.704	Up-regulation
AGC_PKC_PKCa_PRKCA_ST	Q9Y624	F11R	P17252	PRKCA	S274	V278M	278	Missense	distal	4	no	18.112	19.484	EPSD	COSMIC	16.704	Up-regulation
AGC_PKC_PKCa_PRKCA_ST	Q9Y624	F11R	P17252	PRKCA	S274	T269A	269	Missense	distal	-5	no	18.112	17.731	EPSD	COSMIC;GDSC;CCLE	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	Q9Y624	F11R	P17252	PRKCA	S284	V278M	278	Missense	distal	-6	no	18.239	18.350	PhosphoSitePlus	COSMIC	16.704	Up-regulation
AGC_PKC_PKCa_PRKCA_ST	Q9UBS0	RPS6KB2	P17252	PRKCA	S219	A224T	224	Missense	distal	5	no	17.293	17.014	EPSD	COSMIC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	Q9UBS0	RPS6KB2	P17252	PRKCA	S219	V225F	225	Missense	distal	6	no	17.293	17.340	EPSD	COSMIC	16.704	Up-regulation
AGC_PKC_PKCa_PRKCA_ST	Q9UBS0	RPS6KB2	P17252	PRKCA	S410	R413C	413	Missense	distal	3	no	21.803	19.185	EPSD	COSMIC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	Q9UBS0	RPS6KB2	P17252	PRKCA	S410	R413H	413	Missense	distal	3	no	21.803	21.091	EPSD	COSMIC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	Q9UBS0	RPS6KB2	P17252	PRKCA	S416	P421S	421	Missense	distal	5	no	20.048	19.889	EPSD	COSMIC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	Q9UBS0	RPS6KB2	P17252	PRKCA	S416	R413C	413	Missense	distal	-3	no	20.048	17.309	EPSD	COSMIC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	Q9UBS0	RPS6KB2	P17252	PRKCA	S416	R413H	413	Missense	distal	-3	no	20.048	16.192	EPSD	COSMIC	16.704	Loss
AGC_PKC_PKCa_PRKCA_ST	Q9UBS0	RPS6KB2	P17252	PRKCA	S416	P421L	421	Missense	distal	5	no	20.048	19.698	EPSD	COSMIC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	Q9UBS0	RPS6KB2	P17252	PRKCA	S417	P421S	421	Missense	distal	4	no	18.341	18.541	EPSD	COSMIC	16.704	Up-regulation
AGC_PKC_PKCa_PRKCA_ST	Q9UBS0	RPS6KB2	P17252	PRKCA	S417	R413C	413	Missense	distal	-4	no	18.341	16.998	EPSD	COSMIC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	Q9UBS0	RPS6KB2	P17252	PRKCA	S417	R413H	413	Missense	distal	-4	no	18.341	17.767	EPSD	COSMIC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	Q9UBS0	RPS6KB2	P17252	PRKCA	S417	P421L	421	Missense	distal	4	no	18.341	17.749	EPSD	COSMIC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	Q9UBS0	RPS6KB2	P17252	PRKCA	S417	P424L	424	Missense	distal	7	no	18.341	18.308	EPSD	COSMIC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	Q9UBS0	RPS6KB2	P17252	PRKCA	S473	R479H	479	Missense	distal	6	no	19.552	19.474	PhosphoSitePlus	COSMIC;CCLE	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	Q9UBS0	RPS6KB2	P17252	PRKCA	S473	S468P	468	Missense	distal	-5	no	19.552	19.877	PhosphoSitePlus	COSMIC	16.704	Up-regulation
AGC_PKC_PKCa_PRKCA_ST	Q9UBS0	RPS6KB2	P17252	PRKCA	S473	P480Q	480	Missense	distal	7	no	19.552	19.557	PhosphoSitePlus	COSMIC	16.704	Up-regulation
AGC_PKC_PKCa_PRKCA_ST	Q9UBS0	RPS6KB2	P17252	PRKCA	S473	R477H	477	Missense	distal	4	no	19.552	19.269	PhosphoSitePlus	COSMIC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	Q9UBS0	RPS6KB2	P17252	PRKCA	S473	R475G	475	Missense	proximal	2	no	19.552	14.306	PhosphoSitePlus	COSMIC	16.704	Loss
AGC_PKC_PKCa_PRKCA_ST	Q9UBS0	RPS6KB2	P17252	PRKCA	S473	P467H	467	Missense	distal	-6	no	19.552	19.589	PhosphoSitePlus	COSMIC	16.704	Up-regulation
AGC_PKC_PKCa_PRKCA_ST	Q13303	KCNAB2	P17252	PRKCA	S14	T7N	7	Missense	distal	-7	no	20.870	20.868	EPSD	COSMIC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	Q13303	KCNAB2	P17252	PRKCA	S14	R16Q	16	Missense	proximal	2	no	20.870	17.036	EPSD	COSMIC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	Q13303	KCNAB2	P17252	PRKCA	S14	Q17K	17	Missense	distal	3	no	20.870	22.701	EPSD	COSMIC	16.704	Up-regulation
AGC_PKC_PKCa_PRKCA_ST	Q13303	KCNAB2	P17252	PRKCA	S14	G19D	19	Missense	distal	5	no	20.870	20.790	EPSD	COSMIC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	Q13303	KCNAB2	P17252	PRKCA	S20	Q17K	17	Missense	distal	-3	no	15.999	16.830	EPSD	COSMIC	16.704	Gain
AGC_PKC_PKCa_PRKCA_ST	Q13303	KCNAB2	P17252	PRKCA	S26	Y29S	29	Missense	distal	3	no	16.621	17.498	EPSD	COSMIC	16.704	Gain
AGC_PKC_PKCa_PRKCA_ST	Q13303	KCNAB2	P17252	PRKCA	S31	R28W	28	Missense	distal	-3	no	22.857	20.503	EPSD	COSMIC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	Q13303	KCNAB2	P17252	PRKCA	S31	Y29S	29	Missense	proximal	-2	no	22.857	22.283	EPSD	COSMIC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	Q13303	KCNAB2	P17252	PRKCA	S31	R34P	34	Missense	distal	3	no	22.857	21.326	EPSD	COSMIC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	Q13303	KCNAB2	P17252	PRKCA	S111	S112I	112	Missense	proximal	1	no	16.584	18.247	EPSD	COSMIC	16.704	Gain
AGC_PKC_PKCa_PRKCA_ST	Q13303	KCNAB2	P17252	PRKCA	S112	L113H	113	Missense	proximal	1	no	19.218	18.752	EPSD	COSMIC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	Q13303	KCNAB2	P17252	PRKCA	S112	K105N	105	Missense	distal	-7	no	19.218	19.213	EPSD	COSMIC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	Q13303	KCNAB2	P17252	PRKCA	S112	R110W	110	Missense	proximal	-2	no	19.218	17.221	EPSD	COSMIC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	Q13303	KCNAB2	P17252	PRKCA	S112	K118N	118	Missense	distal	6	no	19.218	19.056	EPSD	COSMIC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	Q13303	KCNAB2	P17252	PRKCA	S112	V114I	114	Missense	proximal	2	no	19.218	19.200	EPSD	COSMIC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	Q13303	KCNAB2	P17252	PRKCA	S112	S112I	112	Missense	central	0	yes	19.218	0.000	EPSD	COSMIC	16.704	Loss
AGC_PKC_PKCa_PRKCA_ST	Q13303	KCNAB2	P17252	PRKCA	S112	R110P	110	Missense	proximal	-2	no	19.218	16.176	EPSD	COSMIC	16.704	Loss
AGC_PKC_PKCa_PRKCA_ST	Q13303	KCNAB2	P17252	PRKCA	S266	I259F	259	Missense	distal	-7	no	23.450	23.451	PhosphoSitePlus	COSMIC	16.704	Up-regulation
AGC_PKC_PKCa_PRKCA_ST	Q13303	KCNAB2	P17252	PRKCA	S266	S266F	266	Missense	central	0	yes	23.450	0.000	PhosphoSitePlus	COSMIC	16.704	Loss
AGC_PKC_PKCa_PRKCA_ST	P29972	AQP1	P17252	PRKCA	T157	V153M	153	Missense	distal	-4	no	16.354	17.099	PhosphoSitePlus;EPSD	COSMIC	16.704	Gain
AGC_PKC_PKCa_PRKCA_ST	P01730	CD4	P17252	PRKCA	S433	I435M	435	Missense	proximal	2	no	16.483	17.067	PhosphoSitePlus;EPSD	COSMIC	16.704	Gain
AGC_PKC_PKCa_PRKCA_ST	P01730	CD4	P17252	PRKCA	S440	T444P	444	Missense	distal	4	no	18.086	18.317	EPSD;PhosphoSitePlus	COSMIC;GDSC	16.704	Up-regulation
AGC_PKC_PKCa_PRKCA_ST	P01730	CD4	P17252	PRKCA	S440	I435M	435	Missense	distal	-5	no	18.086	18.490	EPSD;PhosphoSitePlus	COSMIC	16.704	Up-regulation
AGC_PKC_PKCa_PRKCA_ST	Q05209	PTPN12	P17252	PRKCA	S39	M33I	33	Missense	distal	-6	no	23.213	23.119	PhosphoSitePlus;EPSD	COSMIC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	Q05209	PTPN12	P17252	PRKCA	T40	M33I	33	Missense	distal	-7	no	17.374	17.362	EPSD	COSMIC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	Q05209	PTPN12	P17252	PRKCA	S186	H193Y	193	Missense	distal	7	no	17.667	17.687	EPSD	COSMIC	16.704	Up-regulation
AGC_PKC_PKCa_PRKCA_ST	Q05209	PTPN12	P17252	PRKCA	S186	R187P	187	Missense	proximal	1	no	17.667	16.893	EPSD	COSMIC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	Q05209	PTPN12	P17252	PRKCA	T271	V277A	277	Missense	distal	6	no	16.614	16.733	EPSD	COSMIC	16.704	Gain
AGC_PKC_PKCa_PRKCA_ST	Q05209	PTPN12	P17252	PRKCA	T271	H274R	274	Missense	distal	3	no	16.614	17.326	EPSD	COSMIC	16.704	Gain
AGC_PKC_PKCa_PRKCA_ST	Q05209	PTPN12	P17252	PRKCA	T413	L415R	415	Missense	proximal	2	no	12.381	17.368	EPSD	COSMIC	16.704	Gain
AGC_PKC_PKCa_PRKCA_ST	Q05209	PTPN12	P17252	PRKCA	S421	K418R	418	Missense	distal	-3	no	16.471	18.498	EPSD	COSMIC	16.704	Gain
AGC_PKC_PKCa_PRKCA_ST	Q05209	PTPN12	P17252	PRKCA	S421	I423S	423	Missense	proximal	2	no	16.471	16.883	EPSD	COSMIC;GDSC;CCLE	16.704	Gain
AGC_PKC_PKCa_PRKCA_ST	Q05209	PTPN12	P17252	PRKCA	S435	I438M	438	Missense	distal	3	no	17.671	18.952	EPSD;PhosphoSitePlus	COSMIC	16.704	Up-regulation
AGC_PKC_PKCa_PRKCA_ST	Q05209	PTPN12	P17252	PRKCA	S704	E706K	706	Missense	proximal	2	no	14.786	20.065	EPSD	COSMIC	16.704	Gain
AGC_PKC_PKCa_PRKCA_ST	Q05209	PTPN12	P17252	PRKCA	S708	E706K	706	Missense	proximal	-2	no	15.683	18.181	EPSD	COSMIC	16.704	Gain
AGC_PKC_PKCa_PRKCA_ST	Q05209	PTPN12	P17252	PRKCA	S708	Q710K	710	Missense	proximal	2	no	15.683	19.095	EPSD	COSMIC	16.704	Gain
AGC_PKC_PKCa_PRKCA_ST	P21399	ACO1	P17252	PRKCA	S138	L139S	139	Missense	proximal	1	no	20.036	19.210	EPSD;PhosphoSitePlus	COSMIC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	P21399	ACO1	P17252	PRKCA	T702	Y709N	709	Missense	distal	7	no	20.388	20.370	EPSD	COSMIC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	P21399	ACO1	P17252	PRKCA	T702	Y695C	695	Missense	distal	-7	no	20.388	20.374	EPSD	COSMIC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	P21399	ACO1	P17252	PRKCA	S711	R713L	713	Missense	proximal	2	no	19.899	14.912	PhosphoSitePlus;EPSD	COSMIC	16.704	Loss
AGC_PKC_PKCa_PRKCA_ST	P21399	ACO1	P17252	PRKCA	S711	Y709N	709	Missense	proximal	-2	no	19.899	19.430	PhosphoSitePlus;EPSD	COSMIC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	P21399	ACO1	P17252	PRKCA	S711	N707D	707	Missense	distal	-4	no	19.899	19.550	PhosphoSitePlus;EPSD	COSMIC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	P21399	ACO1	P17252	PRKCA	S778	W782R	782	Missense	distal	4	no	17.767	19.303	EPSD	COSMIC	16.704	Up-regulation
AGC_PKC_PKCa_PRKCA_ST	P21399	ACO1	P17252	PRKCA	S778	G775S	775	Missense	distal	-3	no	17.767	18.159	EPSD	COSMIC	16.704	Up-regulation
AGC_PKC_PKCa_PRKCA_ST	P21399	ACO1	P17252	PRKCA	S778	E773Q	773	Missense	distal	-5	no	17.767	17.922	EPSD	COSMIC	16.704	Up-regulation
AGC_PKC_PKCa_PRKCA_ST	P21731	TBXA2R	P17252	PRKCA	S145	A144T	144	Missense	proximal	-1	no	18.398	18.578	PhosphoSitePlus;EPSD	COSMIC;CCLE	16.704	Up-regulation
AGC_PKC_PKCa_PRKCA_ST	P21731	TBXA2R	P17252	PRKCA	S145	A151S	151	Missense	distal	6	no	18.398	18.368	PhosphoSitePlus;EPSD	COSMIC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	P21731	TBXA2R	P17252	PRKCA	S145	R148C	148	Missense	distal	3	no	18.398	15.779	PhosphoSitePlus;EPSD	COSMIC	16.704	Loss
AGC_PKC_PKCa_PRKCA_ST	P21731	TBXA2R	P17252	PRKCA	S145	A151D	151	Missense	distal	6	no	18.398	18.350	PhosphoSitePlus;EPSD	COSMIC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	P21731	TBXA2R	P17252	PRKCA	S145	P141L	141	Missense	distal	-4	no	18.398	18.138	PhosphoSitePlus;EPSD	COSMIC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	P21731	TBXA2R	P17252	PRKCA	S145	R147H	147	Missense	proximal	2	no	18.398	13.374	PhosphoSitePlus;EPSD	COSMIC	16.704	Loss
AGC_PKC_PKCa_PRKCA_ST	P21731	TBXA2R	P17252	PRKCA	S145	S139L	139	Missense	distal	-6	no	18.398	18.332	PhosphoSitePlus;EPSD	COSMIC;GDSC;CCLE	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	P21731	TBXA2R	P17252	PRKCA	S324	R322G	322	Missense	proximal	-2	no	18.282	15.410	EPSD;PhosphoSitePlus	COSMIC;CCLE	16.704	Loss
AGC_PKC_PKCa_PRKCA_ST	P06213	INSR	P17252	PRKCA	S98	L102M	102	Missense	distal	4	no	18.927	19.770	EPSD	COSMIC	16.704	Up-regulation
AGC_PKC_PKCa_PRKCA_ST	P06213	INSR	P17252	PRKCA	S98	F91L	91	Missense	distal	-7	no	18.927	18.929	EPSD	COSMIC	16.704	Up-regulation
AGC_PKC_PKCa_PRKCA_ST	P06213	INSR	P17252	PRKCA	S98	L99M	99	Missense	proximal	1	no	18.927	18.713	EPSD	COSMIC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	P06213	INSR	P17252	PRKCA	S98	R92L	92	Missense	distal	-6	no	18.927	18.788	EPSD	COSMIC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	P06213	INSR	P17252	PRKCA	S98	G95R	95	Missense	distal	-3	no	18.927	22.189	EPSD	COSMIC	16.704	Up-regulation
AGC_PKC_PKCa_PRKCA_ST	P06213	INSR	P17252	PRKCA	S407	S400F	400	Missense	distal	-7	no	17.583	17.575	EPSD	COSMIC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	P06213	INSR	P17252	PRKCA	S407	R410Q	410	Missense	distal	3	no	17.583	15.130	EPSD	COSMIC	16.704	Loss
AGC_PKC_PKCa_PRKCA_ST	P06213	INSR	P17252	PRKCA	S407	R410G	410	Missense	distal	3	no	17.583	16.943	EPSD	COSMIC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	P06213	INSR	P17252	PRKCA	S407	A402S	402	Missense	distal	-5	no	17.583	17.636	EPSD	COSMIC	16.704	Up-regulation
AGC_PKC_PKCa_PRKCA_ST	P06213	INSR	P17252	PRKCA	S407	R413H	413	Missense	distal	6	no	17.583	17.506	EPSD	COSMIC;GDSC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	P06213	INSR	P17252	PRKCA	S407	R410W	410	Missense	distal	3	no	17.583	14.649	EPSD	COSMIC	16.704	Loss
AGC_PKC_PKCa_PRKCA_ST	P06213	INSR	P17252	PRKCA	S841	R843S	843	Missense	proximal	2	no	17.781	13.162	EPSD	COSMIC	16.704	Loss
AGC_PKC_PKCa_PRKCA_ST	P06213	INSR	P17252	PRKCA	S841	V840I	840	Missense	proximal	-1	no	17.781	17.961	EPSD	COSMIC	16.704	Up-regulation
AGC_PKC_PKCa_PRKCA_ST	P06213	INSR	P17252	PRKCA	S841	A848V	848	Missense	distal	7	no	17.781	17.727	EPSD	COSMIC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	P06213	INSR	P17252	PRKCA	S841	M845I	845	Missense	distal	4	no	17.781	16.287	EPSD	COSMIC	16.704	Loss
AGC_PKC_PKCa_PRKCA_ST	P06213	INSR	P17252	PRKCA	S917	G915R	915	Missense	proximal	-2	no	14.265	17.137	EPSD	COSMIC	16.704	Gain
AGC_PKC_PKCa_PRKCA_ST	P06213	INSR	P17252	PRKCA	S922	G919E	919	Missense	distal	-3	no	17.993	16.316	EPSD	COSMIC	16.704	Loss
AGC_PKC_PKCa_PRKCA_ST	P06213	INSR	P17252	PRKCA	S922	R926W	926	Missense	distal	4	no	17.993	16.457	EPSD	COSMIC;GDSC;CCLE	16.704	Loss
AGC_PKC_PKCa_PRKCA_ST	P06213	INSR	P17252	PRKCA	S922	R926Q	926	Missense	distal	4	no	17.993	17.775	EPSD	COSMIC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	P06213	INSR	P17252	PRKCA	S922	G915R	915	Missense	distal	-7	no	17.993	18.002	EPSD	COSMIC	16.704	Up-regulation
AGC_PKC_PKCa_PRKCA_ST	P06213	INSR	P17252	PRKCA	S1064	T1058M	1058	Missense	distal	-6	no	17.717	17.840	PhosphoSitePlus;EPSD	COSMIC	16.704	Up-regulation
AGC_PKC_PKCa_PRKCA_ST	P06213	INSR	P17252	PRKCA	S1064	L1065V	1065	Missense	proximal	1	no	17.717	17.842	PhosphoSitePlus;EPSD	COSMIC;GDSC	16.704	Up-regulation
AGC_PKC_PKCa_PRKCA_ST	P06213	INSR	P17252	PRKCA	S1064	R1068Q	1068	Missense	distal	4	no	17.717	17.499	PhosphoSitePlus;EPSD	COSMIC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	P06213	INSR	P17252	PRKCA	S1064	V1059I	1059	Missense	distal	-5	no	17.717	17.710	PhosphoSitePlus;EPSD	COSMIC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	P06213	INSR	P17252	PRKCA	S1348	G1346R	1346	Missense	proximal	-2	no	15.687	18.559	EPSD	COSMIC	16.704	Gain
AGC_PKC_PKCa_PRKCA_ST	Q02156	PRKCE	P17252	PRKCA	S24	V29A	29	Missense	distal	5	no	18.000	18.384	EPSD	COSMIC	16.704	Up-regulation
AGC_PKC_PKCa_PRKCA_ST	Q02156	PRKCE	P17252	PRKCA	S24	V29M	29	Missense	distal	5	no	18.000	18.408	EPSD	COSMIC	16.704	Up-regulation
AGC_PKC_PKCa_PRKCA_ST	Q02156	PRKCE	P17252	PRKCA	S24	S24L	24	Missense	central	0	yes	18.000	0.000	EPSD	COSMIC;GDSC;CCLE	16.704	Loss
AGC_PKC_PKCa_PRKCA_ST	Q02156	PRKCE	P17252	PRKCA	S24	P20H	20	Missense	distal	-4	no	18.000	17.790	EPSD	COSMIC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	Q02156	PRKCE	P17252	PRKCA	S234	V232G	232	Missense	proximal	-2	no	19.631	19.601	EPSD;PhosphoSitePlus	COSMIC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	Q02156	PRKCE	P17252	PRKCA	S234	Q231H	231	Missense	distal	-3	no	19.631	18.632	EPSD;PhosphoSitePlus	COSMIC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	Q02156	PRKCE	P17252	PRKCA	S234	R236Q	236	Missense	proximal	2	no	19.631	15.797	EPSD;PhosphoSitePlus	COSMIC	16.704	Loss
AGC_PKC_PKCa_PRKCA_ST	Q02156	PRKCE	P17252	PRKCA	S234	G233C	233	Missense	proximal	-1	no	19.631	17.110	EPSD;PhosphoSitePlus	COSMIC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	Q02156	PRKCE	P17252	PRKCA	S368	N361T	361	Missense	distal	-7	no	17.236	17.238	EPSD;PhosphoSitePlus	COSMIC	16.704	Up-regulation
AGC_PKC_PKCa_PRKCA_ST	Q02156	PRKCE	P17252	PRKCA	S368	R372Q	372	Missense	distal	4	no	17.236	17.018	EPSD;PhosphoSitePlus	COSMIC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	Q96PY5	FMNL2	P17252	PRKCA	S216	D220A	220	Missense	distal	4	no	21.073	21.442	EPSD	COSMIC	16.704	Up-regulation
AGC_PKC_PKCa_PRKCA_ST	Q96PY5	FMNL2	P17252	PRKCA	S216	D220Y	220	Missense	distal	4	no	21.073	21.028	EPSD	COSMIC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	Q96PY5	FMNL2	P17252	PRKCA	S216	K217T	217	Missense	proximal	1	no	21.073	20.189	EPSD	COSMIC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	Q96PY5	FMNL2	P17252	PRKCA	T450	R452K	452	Missense	proximal	2	no	16.916	16.494	EPSD	COSMIC	16.704	Loss
AGC_PKC_PKCa_PRKCA_ST	Q96PY5	FMNL2	P17252	PRKCA	T450	Q447E	447	Missense	distal	-3	no	16.916	14.835	EPSD	COSMIC	16.704	Loss
AGC_PKC_PKCa_PRKCA_ST	Q96PY5	FMNL2	P17252	PRKCA	S834	S834G	834	Missense	central	0	yes	19.601	0.000	EPSD	COSMIC	16.704	Loss
AGC_PKC_PKCa_PRKCA_ST	Q96PY5	FMNL2	P17252	PRKCA	S834	A839V	839	Missense	distal	5	no	19.601	19.217	EPSD	COSMIC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	Q96PY5	FMNL2	P17252	PRKCA	S835	S834G	834	Missense	proximal	-1	no	19.529	19.777	EPSD	COSMIC	16.704	Up-regulation
AGC_PKC_PKCa_PRKCA_ST	Q96PY5	FMNL2	P17252	PRKCA	S835	A839V	839	Missense	distal	4	no	19.529	18.191	EPSD	COSMIC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	Q96PY5	FMNL2	P17252	PRKCA	S1018	S1016F	1016	Missense	proximal	-2	no	18.690	18.019	EPSD	COSMIC;GDSC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	P35398	RORA	P17252	PRKCA	S49	S51F	51	Missense	proximal	2	no	18.128	18.445	EPSD	COSMIC	16.704	Up-regulation
AGC_PKC_PKCa_PRKCA_ST	P35398	RORA	P17252	PRKCA	S49	R55K	55	Missense	distal	6	no	18.128	18.116	EPSD	COSMIC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	P35398	RORA	P17252	PRKCA	S49	S54R	54	Missense	distal	5	no	18.128	18.269	EPSD	COSMIC	16.704	Up-regulation
AGC_PKC_PKCa_PRKCA_ST	P35398	RORA	P17252	PRKCA	S155	R153T	153	Missense	proximal	-2	no	17.153	14.259	EPSD	COSMIC	16.704	Loss
AGC_PKC_PKCa_PRKCA_ST	P35398	RORA	P17252	PRKCA	S155	A158S	158	Missense	distal	3	no	17.153	17.359	EPSD	COSMIC	16.704	Up-regulation
AGC_PKC_PKCa_PRKCA_ST	P35398	RORA	P17252	PRKCA	S155	V160L	160	Missense	distal	5	no	17.153	17.243	EPSD	COSMIC	16.704	Up-regulation
AGC_PKC_PKCa_PRKCA_ST	Q05940	SLC18A2	P17252	PRKCA	S50	N56S	56	Missense	distal	6	no	18.249	18.352	EPSD	COSMIC	16.704	Up-regulation
AGC_PKC_PKCa_PRKCA_ST	Q05940	SLC18A2	P17252	PRKCA	S50	H53R	53	Missense	distal	3	no	18.249	18.961	EPSD	COSMIC	16.704	Up-regulation
AGC_PKC_PKCa_PRKCA_ST	Q05940	SLC18A2	P17252	PRKCA	S50	N56T	56	Missense	distal	6	no	18.249	18.303	EPSD	COSMIC	16.704	Up-regulation
AGC_PKC_PKCa_PRKCA_ST	Q05940	SLC18A2	P17252	PRKCA	S279	P272L	272	Missense	distal	-7	no	21.202	21.200	EPSD	COSMIC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	Q05940	SLC18A2	P17252	PRKCA	S279	R274Q	274	Missense	distal	-5	no	21.202	21.050	EPSD	COSMIC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	P35612	ADD2	P17252	PRKCA	S455	Q450H	450	Missense	distal	-5	no	19.179	18.975	EPSD	COSMIC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	P35612	ADD2	P17252	PRKCA	S455	S455N	455	Missense	central	0	yes	19.179	0.000	EPSD	COSMIC	16.704	Loss
AGC_PKC_PKCa_PRKCA_ST	P35612	ADD2	P17252	PRKCA	T631	E624D	624	Missense	distal	-7	no	17.661	17.664	EPSD	COSMIC	16.704	Up-regulation
AGC_PKC_PKCa_PRKCA_ST	P35612	ADD2	P17252	PRKCA	S686	S689G	689	Missense	distal	3	no	16.369	17.120	EPSD	COSMIC	16.704	Gain
AGC_PKC_PKCa_PRKCA_ST	P35612	ADD2	P17252	PRKCA	S686	D682N	682	Missense	distal	-4	no	16.369	16.717	EPSD	COSMIC	16.704	Gain
AGC_PKC_PKCa_PRKCA_ST	P35612	ADD2	P17252	PRKCA	S703	P702S	702	Missense	proximal	-1	no	18.466	18.766	EPSD	COSMIC	16.704	Up-regulation
AGC_PKC_PKCa_PRKCA_ST	P35612	ADD2	P17252	PRKCA	S703	P698L	698	Missense	distal	-5	no	18.466	18.440	EPSD	COSMIC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	P35612	ADD2	P17252	PRKCA	S703	F709Y	709	Missense	distal	6	no	18.466	18.527	EPSD	COSMIC	16.704	Up-regulation
AGC_PKC_PKCa_PRKCA_ST	P35612	ADD2	P17252	PRKCA	S703	F709L	709	Missense	distal	6	no	18.466	18.497	EPSD	COSMIC	16.704	Up-regulation
AGC_PKC_PKCa_PRKCA_ST	P35612	ADD2	P17252	PRKCA	S713	P712S	712	Missense	proximal	-1	no	18.575	18.875	EPSD;PhosphoSitePlus	COSMIC	16.704	Up-regulation
AGC_PKC_PKCa_PRKCA_ST	P35612	ADD2	P17252	PRKCA	S713	F709Y	709	Missense	distal	-4	no	18.575	18.440	EPSD;PhosphoSitePlus	COSMIC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	P35612	ADD2	P17252	PRKCA	S713	S718R	718	Missense	distal	5	no	18.575	18.716	EPSD;PhosphoSitePlus	COSMIC;GDSC;CCLE	16.704	Up-regulation
AGC_PKC_PKCa_PRKCA_ST	P35612	ADD2	P17252	PRKCA	S713	F709L	709	Missense	distal	-4	no	18.575	18.202	EPSD;PhosphoSitePlus	COSMIC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	P35612	ADD2	P17252	PRKCA	S718	P712S	712	Missense	distal	-6	no	19.678	19.709	EPSD	COSMIC	16.704	Up-regulation
AGC_PKC_PKCa_PRKCA_ST	P35612	ADD2	P17252	PRKCA	S718	S718R	718	Missense	central	0	yes	19.678	0.000	EPSD	COSMIC;GDSC;CCLE	16.704	Loss
AGC_PKC_PKCa_PRKCA_ST	Q9NRF2	SH2B1	P17252	PRKCA	S25	E31D	31	Missense	distal	6	no	18.491	18.508	EPSD	COSMIC	16.704	Up-regulation
AGC_PKC_PKCa_PRKCA_ST	Q9NRF2	SH2B1	P17252	PRKCA	S65	A63T	63	Missense	proximal	-2	no	16.928	17.120	EPSD	COSMIC	16.704	Up-regulation
AGC_PKC_PKCa_PRKCA_ST	Q9NRF2	SH2B1	P17252	PRKCA	S144	S139F	139	Missense	distal	-5	no	19.824	19.927	EPSD	COSMIC	16.704	Up-regulation
AGC_PKC_PKCa_PRKCA_ST	Q9NRF2	SH2B1	P17252	PRKCA	S144	K146R	146	Missense	proximal	2	no	19.824	20.245	EPSD	COSMIC	16.704	Up-regulation
AGC_PKC_PKCa_PRKCA_ST	Q9NRF2	SH2B1	P17252	PRKCA	S144	K151N	151	Missense	distal	7	no	19.824	19.704	EPSD	COSMIC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	Q9NRF2	SH2B1	P17252	PRKCA	S154	S154L	154	Missense	central	0	yes	22.641	0.000	EPSD	COSMIC	16.704	Loss
AGC_PKC_PKCa_PRKCA_ST	Q9NRF2	SH2B1	P17252	PRKCA	S154	K151N	151	Missense	distal	-3	no	22.641	20.441	EPSD	COSMIC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	Q9NRF2	SH2B1	P17252	PRKCA	S154	R160L	160	Missense	distal	6	no	22.641	22.559	EPSD	COSMIC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	Q9NRF2	SH2B1	P17252	PRKCA	S157	S154L	154	Missense	distal	-3	no	17.155	15.669	EPSD	COSMIC	16.704	Loss
AGC_PKC_PKCa_PRKCA_ST	Q9NRF2	SH2B1	P17252	PRKCA	S157	K151N	151	Missense	distal	-6	no	17.155	17.031	EPSD	COSMIC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	Q9NRF2	SH2B1	P17252	PRKCA	S157	R160L	160	Missense	distal	3	no	17.155	14.917	EPSD	COSMIC	16.704	Loss
AGC_PKC_PKCa_PRKCA_ST	Q9NRF2	SH2B1	P17252	PRKCA	S161	S154L	154	Missense	distal	-7	no	21.126	21.120	PhosphoSitePlus;EPSD	COSMIC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	Q9NRF2	SH2B1	P17252	PRKCA	S161	R160L	160	Missense	proximal	-1	no	21.126	20.319	PhosphoSitePlus;EPSD	COSMIC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	Q9NRF2	SH2B1	P17252	PRKCA	S165	R160L	160	Missense	distal	-5	no	23.313	23.185	EPSD;PhosphoSitePlus	COSMIC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	Q9NRF2	SH2B1	P17252	PRKCA	S320	P322S	322	Missense	proximal	2	no	16.431	17.014	EPSD	COSMIC	16.704	Gain
AGC_PKC_PKCa_PRKCA_ST	Q9NRF2	SH2B1	P17252	PRKCA	S384	C380R	380	Missense	distal	-4	no	17.651	18.995	EPSD	COSMIC	16.704	Up-regulation
AGC_PKC_PKCa_PRKCA_ST	Q9NRF2	SH2B1	P17252	PRKCA	S384	P377L	377	Missense	distal	-7	no	17.651	17.649	EPSD	COSMIC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	Q9NRF2	SH2B1	P17252	PRKCA	S580	N582K	582	Missense	proximal	2	no	16.188	21.137	EPSD	COSMIC	16.704	Gain
AGC_PKC_PKCa_PRKCA_ST	Q9H1D0	TRPV6	P17252	PRKCA	S182	R179H	179	Missense	distal	-3	no	19.957	16.100	EPSD	COSMIC	16.704	Loss
AGC_PKC_PKCa_PRKCA_ST	Q9H1D0	TRPV6	P17252	PRKCA	S182	R179C	179	Missense	distal	-3	no	19.957	17.217	EPSD	COSMIC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	Q9H1D0	TRPV6	P17252	PRKCA	S182	G189V	189	Missense	distal	7	no	19.957	19.879	EPSD	COSMIC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	Q9H1D0	TRPV6	P17252	PRKCA	S182	A185S	185	Missense	distal	3	no	19.957	20.163	EPSD	COSMIC	16.704	Up-regulation
AGC_PKC_PKCa_PRKCA_ST	Q9H1D0	TRPV6	P17252	PRKCA	S182	A187D	187	Missense	distal	5	no	19.957	19.633	EPSD	COSMIC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	Q9H1D0	TRPV6	P17252	PRKCA	T400	P402R	402	Missense	proximal	2	no	11.863	17.066	EPSD	COSMIC	16.704	Gain
AGC_PKC_PKCa_PRKCA_ST	Q9H1D0	TRPV6	P17252	PRKCA	S401	P402R	402	Missense	proximal	1	no	20.563	21.337	EPSD	COSMIC	16.704	Up-regulation
AGC_PKC_PKCa_PRKCA_ST	Q9H1D0	TRPV6	P17252	PRKCA	S401	R403Q	403	Missense	proximal	2	no	20.563	16.729	EPSD	COSMIC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	Q9H1D0	TRPV6	P17252	PRKCA	S401	L407I	407	Missense	distal	6	no	20.563	20.540	EPSD	COSMIC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	Q9H1D0	TRPV6	P17252	PRKCA	S401	R399H	399	Missense	proximal	-2	no	20.563	16.009	EPSD	COSMIC	16.704	Loss
AGC_PKC_PKCa_PRKCA_ST	Q9H1D0	TRPV6	P17252	PRKCA	S401	R395W	395	Missense	distal	-6	no	20.563	20.278	EPSD	COSMIC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	Q9H1D0	TRPV6	P17252	PRKCA	S401	R399S	399	Missense	proximal	-2	no	20.563	17.261	EPSD	COSMIC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	Q9H1D0	TRPV6	P17252	PRKCA	S401	L407V	407	Missense	distal	6	no	20.563	20.485	EPSD	COSMIC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	Q9H1D0	TRPV6	P17252	PRKCA	S401	D404G	404	Missense	distal	3	no	20.563	21.648	EPSD	COSMIC	16.704	Up-regulation
AGC_PKC_PKCa_PRKCA_ST	Q9H1D0	TRPV6	P17252	PRKCA	S401	R403W	403	Missense	proximal	2	no	20.563	15.123	EPSD	COSMIC	16.704	Loss
AGC_PKC_PKCa_PRKCA_ST	Q9H1D0	TRPV6	P17252	PRKCA	S401	S401R	401	Missense	central	0	yes	20.563	0.000	EPSD	COSMIC	16.704	Loss
AGC_PKC_PKCa_PRKCA_ST	Q9H1D0	TRPV6	P17252	PRKCA	S723	M721T	721	Missense	proximal	-2	no	16.761	15.849	EPSD	COSMIC	16.704	Loss
AGC_PKC_PKCa_PRKCA_ST	Q9H1D0	TRPV6	P17252	PRKCA	S723	R730C	730	Missense	distal	7	no	16.761	16.538	EPSD	COSMIC	16.704	Loss
AGC_PKC_PKCa_PRKCA_ST	Q9H1D0	TRPV6	P17252	PRKCA	S723	P720S	720	Missense	distal	-3	no	16.761	17.740	EPSD	COSMIC	16.704	Up-regulation
AGC_PKC_PKCa_PRKCA_ST	Q9H1D0	TRPV6	P17252	PRKCA	S723	R726Q	726	Missense	distal	3	no	16.761	14.308	EPSD	COSMIC	16.704	Loss
AGC_PKC_PKCa_PRKCA_ST	Q9H1D0	TRPV6	P17252	PRKCA	S723	M721I	721	Missense	proximal	-2	no	16.761	15.155	EPSD	COSMIC	16.704	Loss
AGC_PKC_PKCa_PRKCA_ST	Q9H1D0	TRPV6	P17252	PRKCA	S723	S729T	729	Missense	distal	6	no	16.761	16.713	EPSD	COSMIC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	Q9H1D0	TRPV6	P17252	PRKCA	S723	S729Y	729	Missense	distal	6	no	16.761	16.780	EPSD	COSMIC	16.704	Up-regulation
AGC_PKC_PKCa_PRKCA_ST	Q9H1D0	TRPV6	P17252	PRKCA	S723	S723L	723	Missense	central	0	yes	16.761	0.000	EPSD	COSMIC	16.704	Loss
AGC_PKC_PKCa_PRKCA_ST	Q9H1D0	TRPV6	P17252	PRKCA	T728	M721T	721	Missense	distal	-7	no	20.040	20.035	EPSD	COSMIC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	Q9H1D0	TRPV6	P17252	PRKCA	T728	R730C	730	Missense	proximal	2	no	20.040	15.690	EPSD	COSMIC	16.704	Loss
AGC_PKC_PKCa_PRKCA_ST	Q9H1D0	TRPV6	P17252	PRKCA	T728	R726Q	726	Missense	proximal	-2	no	20.040	18.281	EPSD	COSMIC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	Q9H1D0	TRPV6	P17252	PRKCA	T728	M721I	721	Missense	distal	-7	no	20.040	20.028	EPSD	COSMIC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	Q9H1D0	TRPV6	P17252	PRKCA	T728	S729T	729	Missense	proximal	1	no	20.040	20.367	EPSD	COSMIC	16.704	Up-regulation
AGC_PKC_PKCa_PRKCA_ST	Q9H1D0	TRPV6	P17252	PRKCA	T728	S729Y	729	Missense	proximal	1	no	20.040	20.851	EPSD	COSMIC	16.704	Up-regulation
AGC_PKC_PKCa_PRKCA_ST	Q9H1D0	TRPV6	P17252	PRKCA	T728	S723L	723	Missense	distal	-5	no	20.040	20.339	EPSD	COSMIC	16.704	Up-regulation
AGC_PKC_PKCa_PRKCA_ST	Q9H1D0	TRPV6	P17252	PRKCA	T728	W735L	735	Missense	distal	7	no	20.040	20.177	EPSD	COSMIC	16.704	Up-regulation
AGC_PKC_PKCa_PRKCA_ST	Q9H1D0	TRPV6	P17252	PRKCA	T742	R744S	744	Missense	proximal	2	no	20.794	16.174	PhosphoSitePlus	COSMIC	16.704	Loss
AGC_PKC_PKCa_PRKCA_ST	Q9H1D0	TRPV6	P17252	PRKCA	T742	R748C	748	Missense	distal	6	no	20.794	20.554	PhosphoSitePlus	COSMIC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	Q9H1D0	TRPV6	P17252	PRKCA	T742	R748H	748	Missense	distal	6	no	20.794	20.716	PhosphoSitePlus	COSMIC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	Q9H1D0	TRPV6	P17252	PRKCA	T742	R739P	739	Missense	distal	-3	no	20.794	16.945	PhosphoSitePlus	COSMIC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	Q9H1D0	TRPV6	P17252	PRKCA	T742	R739W	739	Missense	distal	-3	no	20.794	18.440	PhosphoSitePlus	COSMIC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	Q9H1D0	TRPV6	P17252	PRKCA	T742	R739Q	739	Missense	distal	-3	no	20.794	17.936	PhosphoSitePlus	COSMIC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	Q9H1D0	TRPV6	P17252	PRKCA	T742	G741R	741	Missense	proximal	-1	no	20.794	20.933	PhosphoSitePlus	COSMIC	16.704	Up-regulation
AGC_PKC_PKCa_PRKCA_ST	Q9H1D0	TRPV6	P17252	PRKCA	T742	R745S	745	Missense	distal	3	no	20.794	19.402	PhosphoSitePlus	COSMIC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	Q9H1D0	TRPV6	P17252	PRKCA	T742	G749R	749	Missense	distal	7	no	20.794	20.818	PhosphoSitePlus	COSMIC	16.704	Up-regulation
AGC_PKC_PKCa_PRKCA_ST	Q9H1D0	TRPV6	P17252	PRKCA	T742	W735L	735	Missense	distal	-7	no	20.794	20.800	PhosphoSitePlus	COSMIC	16.704	Up-regulation
AGC_PKC_PKCa_PRKCA_ST	O95786	DDX58	P17252	PRKCA	S8	S8G	8	Missense	central	0	yes	21.758	0.000	PhosphoSitePlus;EPSD	COSMIC	16.704	Loss
AGC_PKC_PKCa_PRKCA_ST	O95786	DDX58	P17252	PRKCA	S8	R6Q	6	Missense	proximal	-2	no	21.758	19.999	PhosphoSitePlus;EPSD	COSMIC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	O95786	DDX58	P17252	PRKCA	S308	F310L	310	Missense	proximal	2	no	16.957	16.274	EPSD	COSMIC	16.704	Loss
AGC_PKC_PKCa_PRKCA_ST	O95786	DDX58	P17252	PRKCA	S468	R466Q	466	Missense	proximal	-2	no	19.174	17.415	EPSD	COSMIC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	O95786	DDX58	P17252	PRKCA	S468	D469Y	469	Missense	proximal	1	no	19.174	20.411	EPSD	COSMIC	16.704	Up-regulation
AGC_PKC_PKCa_PRKCA_ST	O95786	DDX58	P17252	PRKCA	S468	R466W	466	Missense	proximal	-2	no	19.174	17.177	EPSD	COSMIC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	O95786	DDX58	P17252	PRKCA	S468	R461C	461	Missense	distal	-7	no	19.174	19.155	EPSD	COSMIC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	O95786	DDX58	P17252	PRKCA	S764	R767H	767	Missense	distal	3	no	17.053	16.341	EPSD	COSMIC;GDSC;CCLE	16.704	Loss
AGC_PKC_PKCa_PRKCA_ST	O95786	DDX58	P17252	PRKCA	S764	S764F	764	Missense	central	0	yes	17.053	0.000	EPSD	COSMIC	16.704	Loss
AGC_PKC_PKCa_PRKCA_ST	O95786	DDX58	P17252	PRKCA	S764	E758K	758	Missense	distal	-6	no	17.053	17.120	EPSD	COSMIC	16.704	Up-regulation
AGC_PKC_PKCa_PRKCA_ST	O95786	DDX58	P17252	PRKCA	S764	M760I	760	Missense	distal	-4	no	17.053	16.339	EPSD	COSMIC	16.704	Loss
AGC_PKC_PKCa_PRKCA_ST	O95786	DDX58	P17252	PRKCA	S764	D763Y	763	Missense	proximal	-1	no	17.053	17.099	EPSD	COSMIC	16.704	Up-regulation
AGC_PKC_PKCa_PRKCA_ST	O95786	DDX58	P17252	PRKCA	S854	P850Q	850	Missense	distal	-4	no	16.897	16.885	EPSD	COSMIC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	O95786	DDX58	P17252	PRKCA	S854	K858R	858	Missense	distal	4	no	16.897	16.726	EPSD	COSMIC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	O95786	DDX58	P17252	PRKCA	S854	R859G	859	Missense	distal	5	no	16.897	16.616	EPSD	COSMIC	16.704	Loss
AGC_PKC_PKCa_PRKCA_ST	P07949	RET	P17252	PRKCA	S6	A4V	4	Missense	proximal	-2	no	17.114	17.358	EPSD	COSMIC	16.704	Up-regulation
AGC_PKC_PKCa_PRKCA_ST	P07949	RET	P17252	PRKCA	S6	A4E	4	Missense	proximal	-2	no	17.114	16.073	EPSD	COSMIC	16.704	Loss
AGC_PKC_PKCa_PRKCA_ST	P07949	RET	P17252	PRKCA	S159	E164K	164	Missense	distal	5	no	18.041	18.455	EPSD	COSMIC	16.704	Up-regulation
AGC_PKC_PKCa_PRKCA_ST	P07949	RET	P17252	PRKCA	S159	R163Q	163	Missense	distal	4	no	18.041	17.823	EPSD	COSMIC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	P07949	RET	P17252	PRKCA	T538	G535R	535	Missense	distal	-3	no	14.360	17.621	EPSD	COSMIC	16.704	Gain
AGC_PKC_PKCa_PRKCA_ST	P07949	RET	P17252	PRKCA	T675	A682V	682	Missense	distal	7	no	18.261	18.206	PhosphoSitePlus	COSMIC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	P07949	RET	P17252	PRKCA	T675	Q681H	681	Missense	distal	6	no	18.261	18.306	PhosphoSitePlus	COSMIC	16.704	Up-regulation
AGC_PKC_PKCa_PRKCA_ST	P07949	RET	P17252	PRKCA	S686	A682V	682	Missense	distal	-4	no	16.759	16.200	EPSD	COSMIC	16.704	Loss
AGC_PKC_PKCa_PRKCA_ST	P07949	RET	P17252	PRKCA	S686	Q681H	681	Missense	distal	-5	no	16.759	16.556	EPSD	COSMIC	16.704	Loss
AGC_PKC_PKCa_PRKCA_ST	P07949	RET	P17252	PRKCA	S686	P684L	684	Missense	proximal	-2	no	16.759	17.113	EPSD	COSMIC	16.704	Up-regulation
AGC_PKC_PKCa_PRKCA_ST	P07949	RET	P17252	PRKCA	S686	S690F	690	Missense	distal	4	no	16.759	16.398	EPSD	COSMIC	16.704	Loss
AGC_PKC_PKCa_PRKCA_ST	P07949	RET	P17252	PRKCA	S686	P684S	684	Missense	proximal	-2	no	16.759	16.500	EPSD	COSMIC	16.704	Loss
AGC_PKC_PKCa_PRKCA_ST	P07949	RET	P17252	PRKCA	S696	D698G	698	Missense	proximal	2	no	20.184	20.217	EPSD	COSMIC	16.704	Up-regulation
AGC_PKC_PKCa_PRKCA_ST	P07949	RET	P17252	PRKCA	S696	S690F	690	Missense	distal	-6	no	20.184	20.099	EPSD	COSMIC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	P07949	RET	P17252	PRKCA	S696	E701K	701	Missense	distal	5	no	20.184	20.598	EPSD	COSMIC	16.704	Up-regulation
AGC_PKC_PKCa_PRKCA_ST	P07949	RET	P17252	PRKCA	S699	E701K	701	Missense	proximal	2	no	12.329	17.608	EPSD	COSMIC	16.704	Gain
AGC_PKC_PKCa_PRKCA_ST	P05556	ITGB1	P17252	PRKCA	S61	T60A	60	Missense	proximal	-1	no	18.513	18.333	EPSD	COSMIC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	P05556	ITGB1	P17252	PRKCA	S209	Q211K	211	Missense	proximal	2	no	13.556	16.968	EPSD	COSMIC	16.704	Gain
AGC_PKC_PKCa_PRKCA_ST	O15519	CFLAR	P17252	PRKCA	S193	P197T	197	Missense	distal	4	no	18.401	18.170	PhosphoSitePlus	COSMIC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	O15519	CFLAR	P17252	PRKCA	S193	A189T	189	Missense	distal	-4	no	18.401	17.652	PhosphoSitePlus	COSMIC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	O15519	CFLAR	P17252	PRKCA	S227	E230D	230	Missense	distal	3	no	17.283	16.796	EPSD	COSMIC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	O15519	CFLAR	P17252	PRKCA	S227	E230K	230	Missense	distal	3	no	17.283	17.899	EPSD	COSMIC	16.704	Up-regulation
AGC_PKC_PKCa_PRKCA_ST	O15519	CFLAR	P17252	PRKCA	S248	P250A	250	Missense	proximal	2	no	16.237	16.741	EPSD	COSMIC	16.704	Gain
AGC_PKC_PKCa_PRKCA_ST	P25098	GRK2	P17252	PRKCA	S29	P24L	24	Missense	distal	-5	no	19.369	19.343	PhosphoSitePlus	COSMIC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	P25098	GRK2	P17252	PRKCA	S29	K30R	30	Missense	proximal	1	no	19.369	19.332	PhosphoSitePlus	COSMIC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	P25098	GRK2	P17252	PRKCA	S38	V42F	42	Missense	distal	4	no	17.479	18.439	EPSD	COSMIC	16.704	Up-regulation
AGC_PKC_PKCa_PRKCA_ST	P25098	GRK2	P17252	PRKCA	S38	R40H	40	Missense	proximal	2	no	17.479	12.455	EPSD	COSMIC;GDSC	16.704	Loss
AGC_PKC_PKCa_PRKCA_ST	P25098	GRK2	P17252	PRKCA	T213	A218T	218	Missense	distal	5	no	18.209	17.930	EPSD	COSMIC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	P25098	GRK2	P17252	PRKCA	T213	M219I	219	Missense	distal	6	no	18.209	18.176	EPSD	COSMIC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	P25098	GRK2	P17252	PRKCA	T213	R209Q	209	Missense	distal	-4	no	18.209	17.831	EPSD	COSMIC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	P25098	GRK2	P17252	PRKCA	S389	R386W	386	Missense	distal	-3	no	20.141	17.787	EPSD	COSMIC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	P25098	GRK2	P17252	PRKCA	S389	G387R	387	Missense	proximal	-2	no	20.141	23.013	EPSD	COSMIC	16.704	Up-regulation
AGC_PKC_PKCa_PRKCA_ST	P08670	VIM	P17252	PRKCA	S2	R4K	4	Missense	proximal	2	no	19.646	19.225	EPSD	COSMIC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	P08670	VIM	P17252	PRKCA	S5	R4K	4	Missense	proximal	-1	no	17.100	17.157	EPSD;PhosphoSitePlus	COSMIC	16.704	Up-regulation
AGC_PKC_PKCa_PRKCA_ST	P08670	VIM	P17252	PRKCA	S7	R4K	4	Missense	distal	-3	no	16.941	14.915	EPSD;PhosphoSitePlus	COSMIC	16.704	Loss
AGC_PKC_PKCa_PRKCA_ST	P08670	VIM	P17252	PRKCA	S8	R4K	4	Missense	distal	-4	no	16.731	16.766	EPSD;PhosphoSitePlus	COSMIC	16.704	Up-regulation
AGC_PKC_PKCa_PRKCA_ST	P08670	VIM	P17252	PRKCA	S9	R4K	4	Missense	distal	-5	no	18.343	18.330	EPSD;PhosphoSitePlus	COSMIC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	P08670	VIM	P17252	PRKCA	S10	R4K	4	Missense	distal	-6	no	24.413	24.406	PhosphoSitePlus;EPSD	COSMIC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	P08670	VIM	P17252	PRKCA	S25	P18L	18	Missense	distal	-7	no	19.761	19.759	EPSD	COSMIC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	P08670	VIM	P17252	PRKCA	S25	S27R	27	Missense	proximal	2	no	19.761	24.381	EPSD	COSMIC	16.704	Up-regulation
AGC_PKC_PKCa_PRKCA_ST	P08670	VIM	P17252	PRKCA	S26	S27R	27	Missense	proximal	1	no	23.535	24.709	EPSD	COSMIC	16.704	Up-regulation
AGC_PKC_PKCa_PRKCA_ST	P08670	VIM	P17252	PRKCA	S29	S27R	27	Missense	proximal	-2	no	15.251	18.553	EPSD	COSMIC	16.704	Gain
AGC_PKC_PKCa_PRKCA_ST	P08670	VIM	P17252	PRKCA	S34	R36H	36	Missense	proximal	2	no	16.913	11.889	EPSD	COSMIC	16.704	Loss
AGC_PKC_PKCa_PRKCA_ST	P08670	VIM	P17252	PRKCA	S34	S27R	27	Missense	distal	-7	no	16.913	16.918	EPSD	COSMIC	16.704	Up-regulation
AGC_PKC_PKCa_PRKCA_ST	P08670	VIM	P17252	PRKCA	S34	S34P	34	Missense	central	0	yes	16.913	0.000	EPSD	COSMIC	16.704	Loss
AGC_PKC_PKCa_PRKCA_ST	P08670	VIM	P17252	PRKCA	S42	R36H	36	Missense	distal	-6	no	17.403	17.335	EPSD	COSMIC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	P08670	VIM	P17252	PRKCA	S47	S51N	51	Missense	distal	4	no	16.757	16.047	EPSD	COSMIC	16.704	Loss
AGC_PKC_PKCa_PRKCA_ST	P08670	VIM	P17252	PRKCA	T48	S55A	55	Missense	distal	7	no	18.727	18.726	EPSD	COSMIC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	P08670	VIM	P17252	PRKCA	T48	S51N	51	Missense	distal	3	no	18.727	18.549	EPSD	COSMIC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	P08670	VIM	P17252	PRKCA	S66	R64H	64	Missense	proximal	-2	no	17.139	12.586	EPSD	COSMIC	16.704	Loss
AGC_PKC_PKCa_PRKCA_ST	P08670	VIM	P17252	PRKCA	S66	G59V	59	Missense	distal	-7	no	17.139	17.135	EPSD	COSMIC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	P08670	VIM	P17252	PRKCA	S66	R71Q	71	Missense	distal	5	no	17.139	17.131	EPSD	COSMIC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	P08670	VIM	P17252	PRKCA	S66	S65F	65	Missense	proximal	-1	no	17.139	16.432	EPSD	COSMIC	16.704	Loss
AGC_PKC_PKCa_PRKCA_ST	P08670	VIM	P17252	PRKCA	S66	R69C	69	Missense	distal	3	no	17.139	14.521	EPSD	COSMIC	16.704	Loss
AGC_PKC_PKCa_PRKCA_ST	P08670	VIM	P17252	PRKCA	S73	V77L	77	Missense	distal	4	no	16.428	16.957	EPSD	COSMIC	16.704	Gain
AGC_PKC_PKCa_PRKCA_ST	P08670	VIM	P17252	PRKCA	S144	D148H	148	Missense	distal	4	no	16.594	16.911	EPSD	COSMIC	16.704	Gain
AGC_PKC_PKCa_PRKCA_ST	P08670	VIM	P17252	PRKCA	S205	N212S	212	Missense	distal	7	no	17.977	18.001	EPSD	COSMIC	16.704	Up-regulation
AGC_PKC_PKCa_PRKCA_ST	P08670	VIM	P17252	PRKCA	S226	E229K	229	Missense	distal	3	no	16.275	16.891	EPSD	COSMIC	16.704	Gain
AGC_PKC_PKCa_PRKCA_ST	P08670	VIM	P17252	PRKCA	S293	Y291C	291	Missense	proximal	-2	no	17.032	18.060	EPSD	COSMIC	16.704	Up-regulation
AGC_PKC_PKCa_PRKCA_ST	Q9UKF7	PITPNC1	P17252	PRKCA	S299	R294W	294	Missense	distal	-5	no	19.762	19.448	PhosphoSitePlus;EPSD	COSMIC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	Q9UKF7	PITPNC1	P17252	PRKCA	S299	R296Q	296	Missense	distal	-3	no	19.762	16.904	PhosphoSitePlus;EPSD	COSMIC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	Q9UKF7	PITPNC1	P17252	PRKCA	S299	R294Q	294	Missense	distal	-5	no	19.762	19.610	PhosphoSitePlus;EPSD	COSMIC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	Q04637	EIF4G1	P17252	PRKCA	T179	E176V	176	Missense	distal	-3	no	17.960	19.208	EPSD	COSMIC	16.704	Up-regulation
AGC_PKC_PKCa_PRKCA_ST	Q04637	EIF4G1	P17252	PRKCA	T179	R183Q	183	Missense	distal	4	no	17.960	17.742	EPSD	COSMIC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	Q04637	EIF4G1	P17252	PRKCA	T179	D184G	184	Missense	distal	5	no	17.960	18.040	EPSD	COSMIC	16.704	Up-regulation
AGC_PKC_PKCa_PRKCA_ST	Q04637	EIF4G1	P17252	PRKCA	T179	P185L	185	Missense	distal	6	no	17.960	17.916	EPSD	COSMIC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	Q04637	EIF4G1	P17252	PRKCA	T179	T179M	179	Missense	central	0	yes	17.960	0.000	EPSD	COSMIC	16.704	Loss
AGC_PKC_PKCa_PRKCA_ST	Q04637	EIF4G1	P17252	PRKCA	T179	T179A	179	Missense	central	0	yes	17.960	0.000	EPSD	COSMIC	16.704	Loss
AGC_PKC_PKCa_PRKCA_ST	Q04637	EIF4G1	P17252	PRKCA	T179	R177C	177	Missense	proximal	-2	no	17.960	16.260	EPSD	COSMIC	16.704	Loss
AGC_PKC_PKCa_PRKCA_ST	Q04637	EIF4G1	P17252	PRKCA	S263	T265K	265	Missense	proximal	2	no	13.382	17.771	EPSD	COSMIC	16.704	Gain
AGC_PKC_PKCa_PRKCA_ST	Q04637	EIF4G1	P17252	PRKCA	S679	S679F	679	Missense	central	0	yes	17.108	0.000	EPSD	COSMIC	16.704	Loss
AGC_PKC_PKCa_PRKCA_ST	Q04637	EIF4G1	P17252	PRKCA	S679	R675H	675	Missense	distal	-4	no	17.108	16.534	EPSD	COSMIC	16.704	Loss
AGC_PKC_PKCa_PRKCA_ST	Q04637	EIF4G1	P17252	PRKCA	S679	G686D	686	Missense	distal	7	no	17.108	17.089	EPSD	COSMIC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	Q04637	EIF4G1	P17252	PRKCA	S679	R681H	681	Missense	proximal	2	no	17.108	12.085	EPSD	COSMIC	16.704	Loss
AGC_PKC_PKCa_PRKCA_ST	Q04637	EIF4G1	P17252	PRKCA	S679	R675Q	675	Missense	distal	-4	no	17.108	16.731	EPSD	COSMIC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	Q04637	EIF4G1	P17252	PRKCA	S679	R681Q	681	Missense	proximal	2	no	17.108	13.274	EPSD	COSMIC	16.704	Loss
AGC_PKC_PKCa_PRKCA_ST	Q04637	EIF4G1	P17252	PRKCA	S704	G698D	698	Missense	distal	-6	no	18.916	18.866	EPSD	COSMIC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	Q04637	EIF4G1	P17252	PRKCA	S704	A697V	697	Missense	distal	-7	no	18.916	18.906	EPSD	COSMIC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	Q04637	EIF4G1	P17252	PRKCA	S704	A697S	697	Missense	distal	-7	no	18.916	18.914	EPSD	COSMIC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	Q04637	EIF4G1	P17252	PRKCA	S704	L699M	699	Missense	distal	-5	no	18.916	18.877	EPSD	COSMIC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	Q04637	EIF4G1	P17252	PRKCA	S766	L768M	768	Missense	proximal	2	no	19.847	20.386	EPSD	COSMIC	16.704	Up-regulation
AGC_PKC_PKCa_PRKCA_ST	Q04637	EIF4G1	P17252	PRKCA	S766	S766F	766	Missense	central	0	yes	19.847	0.000	EPSD	COSMIC	16.704	Loss
AGC_PKC_PKCa_PRKCA_ST	Q04637	EIF4G1	P17252	PRKCA	S766	R762H	762	Missense	distal	-4	no	19.847	19.273	EPSD	COSMIC;CCLE	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	Q04637	EIF4G1	P17252	PRKCA	S766	L771P	771	Missense	distal	5	no	19.847	20.197	EPSD	COSMIC	16.704	Up-regulation
AGC_PKC_PKCa_PRKCA_ST	Q04637	EIF4G1	P17252	PRKCA	S766	D759Y	759	Missense	distal	-7	no	19.847	19.852	EPSD	COSMIC	16.704	Up-regulation
AGC_PKC_PKCa_PRKCA_ST	Q04637	EIF4G1	P17252	PRKCA	S766	R763H	763	Missense	distal	-3	no	19.847	15.991	EPSD	COSMIC	16.704	Loss
AGC_PKC_PKCa_PRKCA_ST	Q04637	EIF4G1	P17252	PRKCA	S895	G897E	897	Missense	proximal	2	no	18.587	18.131	EPSD	COSMIC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	Q04637	EIF4G1	P17252	PRKCA	S895	G897R	897	Missense	proximal	2	no	18.587	23.832	EPSD	COSMIC;GDSC	16.704	Up-regulation
AGC_PKC_PKCa_PRKCA_ST	Q04637	EIF4G1	P17252	PRKCA	S895	R888Q	888	Missense	distal	-7	no	18.587	18.578	EPSD	COSMIC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	Q04637	EIF4G1	P17252	PRKCA	S895	R894C	894	Missense	proximal	-1	no	18.587	15.927	EPSD	COSMIC	16.704	Loss
AGC_PKC_PKCa_PRKCA_ST	Q04637	EIF4G1	P17252	PRKCA	S895	R893W	893	Missense	proximal	-2	no	18.587	16.589	EPSD	COSMIC	16.704	Loss
AGC_PKC_PKCa_PRKCA_ST	Q04637	EIF4G1	P17252	PRKCA	S895	I890V	890	Missense	distal	-5	no	18.587	18.594	EPSD	COSMIC	16.704	Up-regulation
AGC_PKC_PKCa_PRKCA_ST	Q04637	EIF4G1	P17252	PRKCA	S895	R894H	894	Missense	proximal	-1	no	18.587	18.263	EPSD	COSMIC;GDSC;CCLE	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	Q04637	EIF4G1	P17252	PRKCA	S895	I902V	902	Missense	distal	7	no	18.587	18.683	EPSD	COSMIC	16.704	Up-regulation
AGC_PKC_PKCa_PRKCA_ST	Q04637	EIF4G1	P17252	PRKCA	S895	R888H	888	Missense	distal	-7	no	18.587	18.580	EPSD	COSMIC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	Q04637	EIF4G1	P17252	PRKCA	S895	R894W	894	Missense	proximal	-1	no	18.587	17.002	EPSD	COSMIC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	Q04637	EIF4G1	P17252	PRKCA	S895	L896P	896	Missense	proximal	1	no	18.587	18.160	EPSD	COSMIC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	Q04637	EIF4G1	P17252	PRKCA	S1028	G1034D	1034	Missense	distal	6	no	21.932	21.992	EPSD	COSMIC	16.704	Up-regulation
AGC_PKC_PKCa_PRKCA_ST	Q04637	EIF4G1	P17252	PRKCA	S1028	K1026R	1026	Missense	proximal	-2	no	21.932	23.560	EPSD	COSMIC	16.704	Up-regulation
AGC_PKC_PKCa_PRKCA_ST	Q04637	EIF4G1	P17252	PRKCA	S1028	P1035L	1035	Missense	distal	7	no	21.932	21.899	EPSD	COSMIC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	Q04637	EIF4G1	P17252	PRKCA	S1028	G1027D	1027	Missense	proximal	-1	no	21.932	21.189	EPSD	COSMIC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	Q04637	EIF4G1	P17252	PRKCA	S1028	R1031H	1031	Missense	distal	3	no	21.932	21.220	EPSD	COSMIC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	Q04637	EIF4G1	P17252	PRKCA	S1028	G1033S	1033	Missense	distal	5	no	21.932	22.072	EPSD	COSMIC	16.704	Up-regulation
AGC_PKC_PKCa_PRKCA_ST	Q04637	EIF4G1	P17252	PRKCA	S1028	G1034S	1034	Missense	distal	6	no	21.932	22.011	EPSD	COSMIC	16.704	Up-regulation
AGC_PKC_PKCa_PRKCA_ST	Q04637	EIF4G1	P17252	PRKCA	S1028	R1032H	1032	Missense	distal	4	no	21.932	21.650	EPSD	COSMIC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	Q04637	EIF4G1	P17252	PRKCA	S1077	T1073P	1073	Missense	distal	-4	no	16.615	17.105	EPSD	COSMIC	16.704	Gain
AGC_PKC_PKCa_PRKCA_ST	Q04637	EIF4G1	P17252	PRKCA	S1092	L1091R	1091	Missense	proximal	-1	no	16.610	17.416	EPSD	COSMIC	16.704	Gain
AGC_PKC_PKCa_PRKCA_ST	Q04637	EIF4G1	P17252	PRKCA	S1092	G1089W	1089	Missense	distal	-3	no	16.610	17.517	EPSD	COSMIC	16.704	Gain
AGC_PKC_PKCa_PRKCA_ST	Q04637	EIF4G1	P17252	PRKCA	S1097	S1098I	1098	Missense	proximal	1	no	15.839	17.502	EPSD	COSMIC	16.704	Gain
AGC_PKC_PKCa_PRKCA_ST	Q04637	EIF4G1	P17252	PRKCA	S1145	R1150M	1150	Missense	distal	5	no	20.664	20.650	EPSD	COSMIC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	Q04637	EIF4G1	P17252	PRKCA	S1145	R1139H	1139	Missense	distal	-6	no	20.664	20.596	EPSD	COSMIC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	Q04637	EIF4G1	P17252	PRKCA	S1145	E1152K	1152	Missense	distal	7	no	20.664	20.810	EPSD	COSMIC	16.704	Up-regulation
AGC_PKC_PKCa_PRKCA_ST	Q04637	EIF4G1	P17252	PRKCA	S1145	E1149Q	1149	Missense	distal	4	no	20.664	20.815	EPSD	COSMIC	16.704	Up-regulation
AGC_PKC_PKCa_PRKCA_ST	Q04637	EIF4G1	P17252	PRKCA	S1145	R1143M	1143	Missense	proximal	-2	no	20.664	18.683	EPSD	COSMIC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	Q04637	EIF4G1	P17252	PRKCA	S1145	G1151D	1151	Missense	distal	6	no	20.664	20.724	EPSD	COSMIC	16.704	Up-regulation
AGC_PKC_PKCa_PRKCA_ST	Q04637	EIF4G1	P17252	PRKCA	S1145	R1148Q	1148	Missense	distal	3	no	20.664	18.211	EPSD	COSMIC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	Q04637	EIF4G1	P17252	PRKCA	S1147	E1149Q	1149	Missense	proximal	2	no	15.730	17.597	EPSD	COSMIC	16.704	Gain
AGC_PKC_PKCa_PRKCA_ST	Q04637	EIF4G1	P17252	PRKCA	S1164	E1162K	1162	Missense	proximal	-2	no	16.751	19.250	EPSD	COSMIC	16.704	Up-regulation
AGC_PKC_PKCa_PRKCA_ST	Q04637	EIF4G1	P17252	PRKCA	S1164	R1160S	1160	Missense	distal	-4	no	16.751	16.558	EPSD	COSMIC	16.704	Loss
AGC_PKC_PKCa_PRKCA_ST	Q04637	EIF4G1	P17252	PRKCA	S1164	R1170H	1170	Missense	distal	6	no	16.751	16.674	EPSD	COSMIC;GDSC	16.704	Loss
AGC_PKC_PKCa_PRKCA_ST	Q04637	EIF4G1	P17252	PRKCA	S1164	R1166W	1166	Missense	proximal	2	no	16.751	11.311	EPSD	COSMIC	16.704	Loss
AGC_PKC_PKCa_PRKCA_ST	Q04637	EIF4G1	P17252	PRKCA	S1164	R1160P	1160	Missense	distal	-4	no	16.751	16.386	EPSD	COSMIC	16.704	Loss
AGC_PKC_PKCa_PRKCA_ST	Q04637	EIF4G1	P17252	PRKCA	S1164	R1170C	1170	Missense	distal	6	no	16.751	16.512	EPSD	COSMIC	16.704	Loss
AGC_PKC_PKCa_PRKCA_ST	Q04637	EIF4G1	P17252	PRKCA	S1164	R1157W	1157	Missense	distal	-7	no	16.751	16.734	EPSD	COSMIC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	Q04637	EIF4G1	P17252	PRKCA	S1164	E1165D	1165	Missense	proximal	1	no	16.751	16.718	EPSD	COSMIC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	Q04637	EIF4G1	P17252	PRKCA	S1164	E1165Q	1165	Missense	proximal	1	no	16.751	18.201	EPSD	COSMIC	16.704	Up-regulation
AGC_PKC_PKCa_PRKCA_ST	Q04637	EIF4G1	P17252	PRKCA	S1164	R1166C	1166	Missense	proximal	2	no	16.751	12.401	EPSD	COSMIC	16.704	Loss
AGC_PKC_PKCa_PRKCA_ST	Q04637	EIF4G1	P17252	PRKCA	S1185	T1182I	1182	Missense	distal	-3	no	17.449	17.125	PhosphoSitePlus	COSMIC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	Q04637	EIF4G1	P17252	PRKCA	S1185	E1191D	1191	Missense	distal	6	no	17.449	17.466	PhosphoSitePlus	COSMIC	16.704	Up-regulation
AGC_PKC_PKCa_PRKCA_ST	Q04637	EIF4G1	P17252	PRKCA	S1185	R1178W	1178	Missense	distal	-7	no	17.449	17.432	PhosphoSitePlus	COSMIC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	Q04637	EIF4G1	P17252	PRKCA	S1185	S1187F	1187	Missense	proximal	2	no	17.449	17.766	PhosphoSitePlus	COSMIC	16.704	Up-regulation
AGC_PKC_PKCa_PRKCA_ST	Q04637	EIF4G1	P17252	PRKCA	S1185	S1187P	1187	Missense	proximal	2	no	17.449	16.866	PhosphoSitePlus	COSMIC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	Q04637	EIF4G1	P17252	PRKCA	S1185	E1192D	1192	Missense	distal	7	no	17.449	17.501	PhosphoSitePlus	COSMIC	16.704	Up-regulation
AGC_PKC_PKCa_PRKCA_ST	Q04637	EIF4G1	P17252	PRKCA	S1209	R1214W	1214	Missense	distal	5	no	16.733	16.225	EPSD	COSMIC	16.704	Loss
AGC_PKC_PKCa_PRKCA_ST	Q04637	EIF4G1	P17252	PRKCA	S1209	R1216C	1216	Missense	distal	7	no	16.733	16.509	EPSD	COSMIC	16.704	Loss
AGC_PKC_PKCa_PRKCA_ST	Q04637	EIF4G1	P17252	PRKCA	S1209	T1211M	1211	Missense	proximal	2	no	16.733	17.095	EPSD	COSMIC;CCLE	16.704	Up-regulation
AGC_PKC_PKCa_PRKCA_ST	Q04637	EIF4G1	P17252	PRKCA	S1209	R1205C	1205	Missense	distal	-4	no	16.733	15.389	EPSD	COSMIC	16.704	Loss
AGC_PKC_PKCa_PRKCA_ST	Q04637	EIF4G1	P17252	PRKCA	S1209	E1212K	1212	Missense	distal	3	no	16.733	17.349	EPSD	COSMIC	16.704	Up-regulation
AGC_PKC_PKCa_PRKCA_ST	Q04637	EIF4G1	P17252	PRKCA	S1209	R1205H	1205	Missense	distal	-4	no	16.733	16.159	EPSD	COSMIC;GDSC	16.704	Loss
AGC_PKC_PKCa_PRKCA_ST	Q04637	EIF4G1	P17252	PRKCA	S1209	E1202Q	1202	Missense	distal	-7	no	16.733	16.737	EPSD	COSMIC	16.704	Up-regulation
AGC_PKC_PKCa_PRKCA_ST	Q04637	EIF4G1	P17252	PRKCA	S1209	A1208G	1208	Missense	proximal	-1	no	16.733	17.540	EPSD	COSMIC	16.704	Up-regulation
AGC_PKC_PKCa_PRKCA_ST	Q04637	EIF4G1	P17252	PRKCA	S1209	E1212D	1212	Missense	distal	3	no	16.733	16.246	EPSD	COSMIC	16.704	Loss
AGC_PKC_PKCa_PRKCA_ST	P31749	AKT1	P17252	PRKCA	T65	L62R	62	Missense	distal	-3	no	14.781	19.137	EPSD	COSMIC	16.704	Gain
AGC_PKC_PKCa_PRKCA_ST	P31749	AKT1	P17252	PRKCA	S124	G123D	123	Missense	proximal	-1	no	16.846	16.102	EPSD	COSMIC	16.704	Loss
AGC_PKC_PKCa_PRKCA_ST	P31749	AKT1	P17252	PRKCA	S124	D127N	127	Missense	distal	3	no	16.846	17.001	EPSD	COSMIC	16.704	Up-regulation
AGC_PKC_PKCa_PRKCA_ST	P31749	AKT1	P17252	PRKCA	S124	G130R	130	Missense	distal	6	no	16.846	16.995	EPSD	COSMIC	16.704	Up-regulation
AGC_PKC_PKCa_PRKCA_ST	P31749	AKT1	P17252	PRKCA	S246	S240P	240	Missense	distal	-6	no	18.142	18.110	EPSD	COSMIC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	P31749	AKT1	P17252	PRKCA	S246	A250V	250	Missense	distal	4	no	18.142	16.804	EPSD	COSMIC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	P31749	AKT1	P17252	PRKCA	S246	Y253C	253	Missense	distal	7	no	18.142	17.971	EPSD	COSMIC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	P31749	AKT1	P17252	PRKCA	S246	R243H	243	Missense	distal	-3	no	18.142	14.286	EPSD	COSMIC	16.704	Loss
AGC_PKC_PKCa_PRKCA_ST	P31749	AKT1	P17252	PRKCA	S246	S240C	240	Missense	distal	-6	no	18.142	17.846	EPSD	COSMIC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	Q96A00	PPP1R14A	P17252	PRKCA	S16	A20T	20	Missense	distal	4	no	19.223	18.776	EPSD	COSMIC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	Q96A00	PPP1R14A	P17252	PRKCA	S16	P23A	23	Missense	distal	7	no	19.223	19.185	EPSD	COSMIC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	Q96A00	PPP1R14A	P17252	PRKCA	S18	A20T	20	Missense	proximal	2	no	16.986	16.874	EPSD	COSMIC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	Q96A00	PPP1R14A	P17252	PRKCA	S18	P23A	23	Missense	distal	5	no	16.986	16.930	EPSD	COSMIC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	Q96A00	PPP1R14A	P17252	PRKCA	T38	V39I	39	Missense	proximal	1	no	16.401	17.113	PhosphoSitePlus	COSMIC;CCLE	16.704	Gain
AGC_PKC_PKCa_PRKCA_ST	P14598	NCF1	P17252	PRKCA	T356	P349R	349	Missense	distal	-7	no	18.076	18.084	EPSD	COSMIC	16.704	Up-regulation
AGC_PKC_PKCa_PRKCA_ST	Q86UR1	NOXA1	P17252	PRKCA	S239	R241I	241	Missense	proximal	2	no	17.013	11.981	EPSD	COSMIC	16.704	Loss
AGC_PKC_PKCa_PRKCA_ST	Q86UR1	NOXA1	P17252	PRKCA	S239	P240Q	240	Missense	proximal	1	no	17.013	17.670	EPSD	COSMIC	16.704	Up-regulation
AGC_PKC_PKCa_PRKCA_ST	Q86UR1	NOXA1	P17252	PRKCA	S239	S234P	234	Missense	distal	-5	no	17.013	17.338	EPSD	COSMIC	16.704	Up-regulation
AGC_PKC_PKCa_PRKCA_ST	Q86UR1	NOXA1	P17252	PRKCA	S239	H245Y	245	Missense	distal	6	no	17.013	17.037	EPSD	COSMIC	16.704	Up-regulation
AGC_PKC_PKCa_PRKCA_ST	Q86UR1	NOXA1	P17252	PRKCA	S239	S239P	239	Missense	central	0	yes	17.013	0.000	EPSD	COSMIC	16.704	Loss
AGC_PKC_PKCa_PRKCA_ST	Q86UR1	NOXA1	P17252	PRKCA	S336	G342D	342	Missense	distal	6	no	18.932	18.992	EPSD	COSMIC	16.704	Up-regulation
AGC_PKC_PKCa_PRKCA_ST	Q03721	KCNC4	P17252	PRKCA	T49	T45M	45	Missense	distal	-4	no	17.971	18.905	EPSD	COSMIC	16.704	Up-regulation
AGC_PKC_PKCa_PRKCA_ST	Q03721	KCNC4	P17252	PRKCA	S577	D581H	581	Missense	distal	4	no	17.833	18.150	EPSD	COSMIC	16.704	Up-regulation
AGC_PKC_PKCa_PRKCA_ST	Q03721	KCNC4	P17252	PRKCA	S577	R580Q	580	Missense	distal	3	no	17.833	15.380	EPSD	COSMIC	16.704	Loss
AGC_PKC_PKCa_PRKCA_ST	Q03721	KCNC4	P17252	PRKCA	T578	D581H	581	Missense	distal	3	no	21.447	22.460	EPSD	COSMIC	16.704	Up-regulation
AGC_PKC_PKCa_PRKCA_ST	Q03721	KCNC4	P17252	PRKCA	T578	R580Q	580	Missense	proximal	2	no	21.447	17.613	EPSD	COSMIC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	P36897	TGFBR1	P17252	PRKCA	T200	L195F	195	Missense	distal	-5	no	16.891	16.695	PhosphoSitePlus	COSMIC	16.704	Loss
AGC_PKC_PKCa_PRKCA_ST	P36897	TGFBR1	P17252	PRKCA	T200	L193S	193	Missense	distal	-7	no	16.891	16.897	PhosphoSitePlus	COSMIC	16.704	Up-regulation
AGC_PKC_PKCa_PRKCA_ST	P36897	TGFBR1	P17252	PRKCA	T200	I201S	201	Missense	proximal	1	no	16.891	15.229	PhosphoSitePlus	COSMIC	16.704	Loss
AGC_PKC_PKCa_PRKCA_ST	P36897	TGFBR1	P17252	PRKCA	T200	I201V	201	Missense	proximal	1	no	16.891	16.180	PhosphoSitePlus	COSMIC	16.704	Loss
AGC_PKC_PKCa_PRKCA_ST	P36897	TGFBR1	P17252	PRKCA	T200	I205V	205	Missense	distal	5	no	16.891	16.804	PhosphoSitePlus	COSMIC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	P36897	TGFBR1	P17252	PRKCA	T200	I205F	205	Missense	distal	5	no	16.891	17.119	PhosphoSitePlus	COSMIC	16.704	Up-regulation
AGC_PKC_PKCa_PRKCA_ST	P36897	TGFBR1	P17252	PRKCA	T296	T298K	298	Missense	proximal	2	no	13.104	17.492	EPSD	COSMIC	16.704	Gain
AGC_PKC_PKCa_PRKCA_ST	P36897	TGFBR1	P17252	PRKCA	T296	T298R	298	Missense	proximal	2	no	13.104	17.914	EPSD	COSMIC	16.704	Gain
AGC_PKC_PKCa_PRKCA_ST	P46940	IQGAP1	P17252	PRKCA	S86	V90M	90	Missense	distal	4	no	16.551	17.923	EPSD	COSMIC	16.704	Gain
AGC_PKC_PKCa_PRKCA_ST	P46940	IQGAP1	P17252	PRKCA	S91	K88T	88	Missense	distal	-3	no	18.228	16.091	EPSD	COSMIC	16.704	Loss
AGC_PKC_PKCa_PRKCA_ST	P46940	IQGAP1	P17252	PRKCA	S91	V90M	90	Missense	proximal	-1	no	18.228	20.350	EPSD	COSMIC	16.704	Up-regulation
AGC_PKC_PKCa_PRKCA_ST	P46940	IQGAP1	P17252	PRKCA	S91	L92P	92	Missense	proximal	1	no	18.228	17.801	EPSD	COSMIC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	P46940	IQGAP1	P17252	PRKCA	S280	A273S	273	Missense	distal	-7	no	17.016	17.014	EPSD	COSMIC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	P46940	IQGAP1	P17252	PRKCA	S644	A645V	645	Missense	proximal	1	no	17.321	17.475	EPSD	COSMIC	16.704	Up-regulation
AGC_PKC_PKCa_PRKCA_ST	P46940	IQGAP1	P17252	PRKCA	S804	D807G	807	Missense	distal	3	no	16.280	17.365	EPSD	COSMIC	16.704	Gain
AGC_PKC_PKCa_PRKCA_ST	P46940	IQGAP1	P17252	PRKCA	S934	S932F	932	Missense	proximal	-2	no	17.279	16.608	EPSD	COSMIC	16.704	Loss
AGC_PKC_PKCa_PRKCA_ST	P46940	IQGAP1	P17252	PRKCA	S1104	Q1105H	1105	Missense	proximal	1	no	18.161	17.465	EPSD	COSMIC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	P46940	IQGAP1	P17252	PRKCA	S1104	S1110G	1110	Missense	distal	6	no	18.161	18.083	EPSD	COSMIC;GDSC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	P46940	IQGAP1	P17252	PRKCA	S1133	R1130W	1130	Missense	distal	-3	no	17.028	14.674	EPSD	COSMIC	16.704	Loss
AGC_PKC_PKCa_PRKCA_ST	P46940	IQGAP1	P17252	PRKCA	S1227	R1223Q	1223	Missense	distal	-4	no	17.528	17.151	EPSD	COSMIC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	P46940	IQGAP1	P17252	PRKCA	S1443	V1444I	1444	Missense	proximal	1	no	21.080	21.791	PhosphoSitePlus	COSMIC	16.704	Up-regulation
AGC_PKC_PKCa_PRKCA_ST	P46940	IQGAP1	P17252	PRKCA	S1443	N1449K	1449	Missense	distal	6	no	21.080	21.241	PhosphoSitePlus	COSMIC	16.704	Up-regulation
AGC_PKC_PKCa_PRKCA_ST	P10588	NR2F6	P17252	PRKCA	S83	N87K	87	Missense	distal	4	no	24.511	25.638	PhosphoSitePlus	COSMIC	16.704	Up-regulation
AGC_PKC_PKCa_PRKCA_ST	P10588	NR2F6	P17252	PRKCA	S83	L88F	88	Missense	distal	5	no	24.511	24.735	PhosphoSitePlus	COSMIC;CCLE	16.704	Up-regulation
AGC_PKC_PKCa_PRKCA_ST	P10588	NR2F6	P17252	PRKCA	S83	S78C	78	Missense	distal	-5	no	24.511	24.262	PhosphoSitePlus	COSMIC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	P10588	NR2F6	P17252	PRKCA	S89	N87K	87	Missense	proximal	-2	no	16.237	17.806	EPSD	COSMIC	16.704	Gain
AGC_PKC_PKCa_PRKCA_ST	Q9UH77	KLHL3	P17252	PRKCA	S9	E4K	4	Missense	distal	-5	no	16.900	17.194	EPSD	COSMIC	16.704	Up-regulation
AGC_PKC_PKCa_PRKCA_ST	Q9UH77	KLHL3	P17252	PRKCA	S10	E4K	4	Missense	distal	-6	no	17.261	17.329	EPSD	COSMIC	16.704	Up-regulation
AGC_PKC_PKCa_PRKCA_ST	Q9UH77	KLHL3	P17252	PRKCA	S376	M380I	380	Missense	distal	4	no	17.233	15.738	EPSD	COSMIC	16.704	Loss
AGC_PKC_PKCa_PRKCA_ST	Q9UH77	KLHL3	P17252	PRKCA	S376	I377T	377	Missense	proximal	1	no	17.233	15.897	EPSD	COSMIC	16.704	Loss
AGC_PKC_PKCa_PRKCA_ST	Q9UH77	KLHL3	P17252	PRKCA	S376	D372N	372	Missense	distal	-4	no	17.233	17.582	EPSD	COSMIC	16.704	Up-regulation
AGC_PKC_PKCa_PRKCA_ST	Q9UH77	KLHL3	P17252	PRKCA	S376	Q373K	373	Missense	distal	-3	no	17.233	18.065	EPSD	COSMIC	16.704	Up-regulation
AGC_PKC_PKCa_PRKCA_ST	Q9UH77	KLHL3	P17252	PRKCA	S376	R383L	383	Missense	distal	7	no	17.233	17.190	EPSD	COSMIC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	Q9UH77	KLHL3	P17252	PRKCA	S433	M427I	427	Missense	distal	-6	no	18.860	18.766	PhosphoSitePlus	COSMIC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	Q9UH77	KLHL3	P17252	PRKCA	S433	V438I	438	Missense	distal	5	no	18.860	18.947	PhosphoSitePlus	COSMIC	16.704	Up-regulation
AGC_PKC_PKCa_PRKCA_ST	Q9UH77	KLHL3	P17252	PRKCA	S433	P426L	426	Missense	distal	-7	no	18.860	18.857	PhosphoSitePlus	COSMIC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	Q9UH77	KLHL3	P17252	PRKCA	S433	R430W	430	Missense	distal	-3	no	18.860	16.506	PhosphoSitePlus	COSMIC	16.704	Loss
AGC_PKC_PKCa_PRKCA_ST	Q9UH77	KLHL3	P17252	PRKCA	S433	G435R	435	Missense	proximal	2	no	18.860	24.105	PhosphoSitePlus	COSMIC	16.704	Up-regulation
AGC_PKC_PKCa_PRKCA_ST	P11234	RALB	P17252	PRKCA	S6	N4K	4	Missense	proximal	-2	no	16.700	18.269	EPSD	COSMIC	16.704	Gain
AGC_PKC_PKCa_PRKCA_ST	P11234	RALB	P17252	PRKCA	S6	A13D	13	Missense	distal	7	no	16.700	16.705	EPSD	COSMIC	16.704	Gain
AGC_PKC_PKCa_PRKCA_ST	P11234	RALB	P17252	PRKCA	S11	N4K	4	Missense	distal	-7	no	16.760	16.765	EPSD	COSMIC	16.704	Up-regulation
AGC_PKC_PKCa_PRKCA_ST	P11234	RALB	P17252	PRKCA	S11	A13D	13	Missense	proximal	2	no	16.760	16.179	EPSD	COSMIC	16.704	Loss
AGC_PKC_PKCa_PRKCA_ST	P11234	RALB	P17252	PRKCA	S11	K16R	16	Missense	distal	5	no	16.760	16.616	EPSD	COSMIC	16.704	Loss
AGC_PKC_PKCa_PRKCA_ST	P11234	RALB	P17252	PRKCA	S50	P45T	45	Missense	distal	-5	no	20.678	20.680	EPSD	COSMIC	16.704	Up-regulation
AGC_PKC_PKCa_PRKCA_ST	P11234	RALB	P17252	PRKCA	S198	K200I	200	Missense	proximal	2	no	18.923	14.313	PhosphoSitePlus	COSMIC	16.704	Loss
AGC_PKC_PKCa_PRKCA_ST	P11234	RALB	P17252	PRKCA	S198	K197R	197	Missense	proximal	-1	no	18.923	18.866	PhosphoSitePlus	COSMIC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	Q13522	PPP1R1A	P17252	PRKCA	T35	R32C	32	Missense	distal	-3	no	17.620	14.881	EPSD	COSMIC	16.704	Loss
AGC_PKC_PKCa_PRKCA_ST	Q13522	PPP1R1A	P17252	PRKCA	T35	P36S	36	Missense	proximal	1	no	17.620	17.221	EPSD	COSMIC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	Q13522	PPP1R1A	P17252	PRKCA	T35	R31M	31	Missense	distal	-4	no	17.620	17.699	EPSD	COSMIC;CCLE	16.704	Up-regulation
AGC_PKC_PKCa_PRKCA_ST	Q13522	PPP1R1A	P17252	PRKCA	S67	R69Q	69	Missense	proximal	2	no	19.017	15.183	PhosphoSitePlus;EPSD	COSMIC;GDSC;CCLE	16.704	Loss
AGC_PKC_PKCa_PRKCA_ST	Q9BQE3	TUBA1C	P17252	PRKCA	T82	R84C	84	Missense	proximal	2	no	19.353	15.003	EPSD	COSMIC;GDSC;CCLE	16.704	Loss
AGC_PKC_PKCa_PRKCA_ST	Q9BQE3	TUBA1C	P17252	PRKCA	S158	E155K	155	Missense	distal	-3	no	16.944	19.856	EPSD;PhosphoSitePlus	COSMIC	16.704	Up-regulation
AGC_PKC_PKCa_PRKCA_ST	Q9BQE3	TUBA1C	P17252	PRKCA	S158	R156H	156	Missense	proximal	-2	no	16.944	12.391	EPSD;PhosphoSitePlus	COSMIC	16.704	Loss
AGC_PKC_PKCa_PRKCA_ST	Q9BQE3	TUBA1C	P17252	PRKCA	S158	Y161S	161	Missense	distal	3	no	16.944	17.821	EPSD;PhosphoSitePlus	COSMIC	16.704	Up-regulation
AGC_PKC_PKCa_PRKCA_ST	Q9BQE3	TUBA1C	P17252	PRKCA	S165	Y161S	161	Missense	distal	-4	no	17.652	17.846	PhosphoSitePlus;EPSD	COSMIC	16.704	Up-regulation
AGC_PKC_PKCa_PRKCA_ST	Q9BQE3	TUBA1C	P17252	PRKCA	S232	N226S	226	Missense	distal	-6	no	17.007	17.064	EPSD	COSMIC	16.704	Up-regulation
AGC_PKC_PKCa_PRKCA_ST	P52566	ARHGDIB	P17252	PRKCA	T2	P8R	8	Missense	distal	6	no	17.817	17.855	EPSD	COSMIC;GDSC;CCLE	16.704	Up-regulation
AGC_PKC_PKCa_PRKCA_ST	P52566	ARHGDIB	P17252	PRKCA	T129	K124N	124	Missense	distal	-5	no	17.120	16.777	EPSD	COSMIC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	P52566	ARHGDIB	P17252	PRKCA	S194	E190K	190	Missense	distal	-4	no	18.678	19.410	EPSD	COSMIC	16.704	Up-regulation
AGC_PKC_PKCa_PRKCA_ST	Q15139	PRKD1	P17252	PRKCA	S153	A158V	158	Missense	distal	5	no	20.548	20.164	EPSD	COSMIC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	Q15139	PRKD1	P17252	PRKCA	S153	H152Y	152	Missense	proximal	-1	no	20.548	20.034	EPSD	COSMIC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	Q15139	PRKD1	P17252	PRKCA	S153	P146L	146	Missense	distal	-7	no	20.548	20.545	EPSD	COSMIC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	Q15139	PRKD1	P17252	PRKCA	S153	P146S	146	Missense	distal	-7	no	20.548	20.551	EPSD	COSMIC;CCLE	16.704	Up-regulation
AGC_PKC_PKCa_PRKCA_ST	Q15139	PRKD1	P17252	PRKCA	S153	R155K	155	Missense	proximal	2	no	20.548	20.126	EPSD	COSMIC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	Q15139	PRKD1	P17252	PRKCA	S205	R201Q	201	Missense	distal	-4	no	19.048	18.671	EPSD	COSMIC;GDSC;CCLE	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	Q15139	PRKD1	P17252	PRKCA	S205	R200K	200	Missense	distal	-5	no	19.048	19.035	EPSD	COSMIC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	Q15139	PRKD1	P17252	PRKCA	S412	S412F	412	Missense	central	0	yes	20.971	0.000	EPSD	COSMIC	16.704	Loss
AGC_PKC_PKCa_PRKCA_ST	Q15139	PRKD1	P17252	PRKCA	S412	Q411H	411	Missense	proximal	-1	no	20.971	21.465	EPSD	COSMIC	16.704	Up-regulation
AGC_PKC_PKCa_PRKCA_ST	Q15139	PRKD1	P17252	PRKCA	S412	V413D	413	Missense	proximal	1	no	20.971	19.594	EPSD	COSMIC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	Q15139	PRKD1	P17252	PRKCA	S412	Q411L	411	Missense	proximal	-1	no	20.971	20.982	EPSD	COSMIC	16.704	Up-regulation
AGC_PKC_PKCa_PRKCA_ST	Q15139	PRKD1	P17252	PRKCA	S420	V413D	413	Missense	distal	-7	no	17.272	17.276	EPSD	COSMIC	16.704	Up-regulation
AGC_PKC_PKCa_PRKCA_ST	Q15139	PRKD1	P17252	PRKCA	S420	S420F	420	Missense	central	0	yes	17.272	0.000	EPSD	COSMIC	16.704	Loss
AGC_PKC_PKCa_PRKCA_ST	Q15139	PRKD1	P17252	PRKCA	S421	S420F	420	Missense	proximal	-1	no	18.202	17.495	EPSD	COSMIC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	Q15139	PRKD1	P17252	PRKCA	S448	I451V	451	Missense	distal	3	no	16.142	16.838	EPSD	COSMIC	16.704	Gain
AGC_PKC_PKCa_PRKCA_ST	Q15139	PRKD1	P17252	PRKCA	S548	P545S	545	Missense	distal	-3	no	15.823	16.801	EPSD	COSMIC	16.704	Gain
AGC_PKC_PKCa_PRKCA_ST	Q15139	PRKD1	P17252	PRKCA	S738	G735V	735	Missense	distal	-3	no	20.313	19.885	PhosphoSitePlus;EPSD	COSMIC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	Q15139	PRKD1	P17252	PRKCA	S738	V743L	743	Missense	distal	5	no	20.313	20.403	PhosphoSitePlus;EPSD	COSMIC	16.704	Up-regulation
AGC_PKC_PKCa_PRKCA_ST	Q15139	PRKD1	P17252	PRKCA	S738	A731D	731	Missense	distal	-7	no	20.313	20.307	PhosphoSitePlus;EPSD	COSMIC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	Q15139	PRKD1	P17252	PRKCA	S742	A748T	748	Missense	distal	6	no	19.960	19.882	EPSD;PhosphoSitePlus	COSMIC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	Q15139	PRKD1	P17252	PRKCA	S742	G735V	735	Missense	distal	-7	no	19.960	19.956	EPSD;PhosphoSitePlus	COSMIC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	Q15139	PRKD1	P17252	PRKCA	S742	V743L	743	Missense	proximal	1	no	19.960	19.835	EPSD;PhosphoSitePlus	COSMIC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	Q15139	PRKD1	P17252	PRKCA	S742	T746I	746	Missense	distal	4	no	19.960	18.947	EPSD;PhosphoSitePlus	COSMIC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	Q15139	PRKD1	P17252	PRKCA	S829	Y828H	828	Missense	proximal	-1	no	19.730	20.244	EPSD	COSMIC	16.704	Up-regulation
AGC_PKC_PKCa_PRKCA_ST	P55087	AQP4	P17252	PRKCA	S180	R182W	182	Missense	proximal	2	no	22.148	16.709	PhosphoSitePlus	COSMIC;GDSC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	P17302	GJA1	P17252	PRKCA	S262	P256T	256	Missense	distal	-6	no	18.371	18.277	EPSD	COSMIC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	P17302	GJA1	P17252	PRKCA	S262	D259Y	259	Missense	distal	-3	no	18.371	18.853	EPSD	COSMIC	16.704	Up-regulation
AGC_PKC_PKCa_PRKCA_ST	P17302	GJA1	P17252	PRKCA	S296	R299L	299	Missense	distal	3	no	17.041	14.803	EPSD	COSMIC;GDSC;CCLE	16.704	Loss
AGC_PKC_PKCa_PRKCA_ST	P17302	GJA1	P17252	PRKCA	S296	N302S	302	Missense	distal	6	no	17.041	17.144	EPSD	COSMIC	16.704	Up-regulation
AGC_PKC_PKCa_PRKCA_ST	P17302	GJA1	P17252	PRKCA	S344	D340Y	340	Missense	distal	-4	no	18.437	18.922	EPSD	COSMIC	16.704	Up-regulation
AGC_PKC_PKCa_PRKCA_ST	P17302	GJA1	P17252	PRKCA	S344	L347P	347	Missense	distal	3	no	18.437	19.144	EPSD	COSMIC;GDSC;CCLE	16.704	Up-regulation
AGC_PKC_PKCa_PRKCA_ST	P17302	GJA1	P17252	PRKCA	S364	P363L	363	Missense	proximal	-1	no	19.138	19.018	EPSD	COSMIC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	P17302	GJA1	P17252	PRKCA	S364	R370S	370	Missense	distal	6	no	19.138	19.067	EPSD	COSMIC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	P17302	GJA1	P17252	PRKCA	S365	P363L	363	Missense	proximal	-2	no	16.563	16.917	EPSD	COSMIC	16.704	Gain
AGC_PKC_PKCa_PRKCA_ST	P17302	GJA1	P17252	PRKCA	S368	P363L	363	Missense	distal	-5	no	19.498	19.472	EPSD;PhosphoSitePlus	COSMIC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	P17302	GJA1	P17252	PRKCA	S368	R370S	370	Missense	proximal	2	no	19.498	14.878	EPSD;PhosphoSitePlus	COSMIC	16.704	Loss
AGC_PKC_PKCa_PRKCA_ST	P17302	GJA1	P17252	PRKCA	S372	R370S	370	Missense	proximal	-2	no	19.465	16.163	PhosphoSitePlus;EPSD	COSMIC	16.704	Loss
AGC_PKC_PKCa_PRKCA_ST	P17302	GJA1	P17252	PRKCA	S373	R370S	370	Missense	distal	-3	no	16.953	14.083	EPSD	COSMIC	16.704	Loss
AGC_PKC_PKCa_PRKCA_ST	P00533	EGFR	P17252	PRKCA	S227	G225C	225	Missense	proximal	-2	no	16.405	17.577	EPSD	COSMIC	16.704	Gain
AGC_PKC_PKCa_PRKCA_ST	P00533	EGFR	P17252	PRKCA	S227	C231S	231	Missense	distal	4	no	16.405	17.560	EPSD	COSMIC	16.704	Gain
AGC_PKC_PKCa_PRKCA_ST	P00533	EGFR	P17252	PRKCA	S645	I643V	643	Missense	proximal	-2	no	16.141	16.887	EPSD	COSMIC	16.704	Gain
AGC_PKC_PKCa_PRKCA_ST	P00533	EGFR	P17252	PRKCA	T678	R680Q	680	Missense	proximal	2	no	23.102	19.268	PhosphoSitePlus	COSMIC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	P00533	EGFR	P17252	PRKCA	T678	V674F	674	Missense	distal	-4	no	23.102	23.516	PhosphoSitePlus	COSMIC	16.704	Up-regulation
AGC_PKC_PKCa_PRKCA_ST	P00533	EGFR	P17252	PRKCA	T678	R675Q	675	Missense	distal	-3	no	23.102	20.244	PhosphoSitePlus	COSMIC;GDSC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	P00533	EGFR	P17252	PRKCA	T678	R680W	680	Missense	proximal	2	no	23.102	17.662	PhosphoSitePlus	COSMIC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	P00533	EGFR	P17252	PRKCA	T678	H672Y	672	Missense	distal	-6	no	23.102	23.043	PhosphoSitePlus	COSMIC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	P00533	EGFR	P17252	PRKCA	T678	R680G	680	Missense	proximal	2	no	23.102	17.857	PhosphoSitePlus	COSMIC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	P00533	EGFR	P17252	PRKCA	T678	K676R	676	Missense	proximal	-2	no	23.102	24.729	PhosphoSitePlus	COSMIC	16.704	Up-regulation
AGC_PKC_PKCa_PRKCA_ST	P00533	EGFR	P17252	PRKCA	T678	R671C	671	Missense	distal	-7	no	23.102	23.083	PhosphoSitePlus	COSMIC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	P00533	EGFR	P17252	PRKCA	T678	R677C	677	Missense	proximal	-1	no	23.102	20.442	PhosphoSitePlus	COSMIC;GDSC;CCLE	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	P00533	EGFR	P17252	PRKCA	T678	R671H	671	Missense	distal	-7	no	23.102	23.095	PhosphoSitePlus	COSMIC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	P00533	EGFR	P17252	PRKCA	S752	A750T	750	Missense	proximal	-2	no	16.571	16.763	EPSD	COSMIC	16.704	Gain
AGC_PKC_PKCa_PRKCA_ST	P00533	EGFR	P17252	PRKCA	S752	K754R	754	Missense	proximal	2	no	16.571	16.993	EPSD	COSMIC	16.704	Gain
AGC_PKC_PKCa_PRKCA_ST	P00533	EGFR	P17252	PRKCA	S752	E749K	749	Missense	distal	-3	no	16.571	19.483	EPSD	COSMIC	16.704	Gain
AGC_PKC_PKCa_PRKCA_ST	P00533	EGFR	P17252	PRKCA	S752	N756S	756	Missense	distal	4	no	16.571	17.281	EPSD	COSMIC	16.704	Gain
AGC_PKC_PKCa_PRKCA_ST	P00533	EGFR	P17252	PRKCA	S752	N756Y	756	Missense	distal	4	no	16.571	16.884	EPSD	COSMIC	16.704	Gain
AGC_PKC_PKCa_PRKCA_ST	P00533	EGFR	P17252	PRKCA	S752	A755G	755	Missense	distal	3	no	16.571	17.529	EPSD	COSMIC	16.704	Gain
AGC_PKC_PKCa_PRKCA_ST	P00533	EGFR	P17252	PRKCA	S752	E749V	749	Missense	distal	-3	no	16.571	17.820	EPSD	COSMIC	16.704	Gain
AGC_PKC_PKCa_PRKCA_ST	P00533	EGFR	P17252	PRKCA	S752	E749G	749	Missense	distal	-3	no	16.571	18.248	EPSD	COSMIC	16.704	Gain
AGC_PKC_PKCa_PRKCA_ST	P00533	EGFR	P17252	PRKCA	S752	P753F	753	Missense	proximal	1	no	16.571	17.656	EPSD	COSMIC	16.704	Gain
AGC_PKC_PKCa_PRKCA_ST	P00533	EGFR	P17252	PRKCA	S1162	A1155D	1155	Missense	distal	-7	no	16.914	16.908	EPSD	COSMIC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	P00533	EGFR	P17252	PRKCA	S1162	S1162N	1162	Missense	central	0	yes	16.914	0.000	EPSD	COSMIC	16.704	Loss
AGC_PKC_PKCa_PRKCA_ST	P00533	EGFR	P17252	PRKCA	S1162	Q1159H	1159	Missense	distal	-3	no	16.914	15.916	EPSD	COSMIC;GDSC;CCLE	16.704	Loss
AGC_PKC_PKCa_PRKCA_ST	P00533	EGFR	P17252	PRKCA	S1162	L1167V	1167	Missense	distal	5	no	16.914	16.824	EPSD	COSMIC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	P00533	EGFR	P17252	PRKCA	S1162	D1168Y	1168	Missense	distal	6	no	16.914	16.951	EPSD	COSMIC	16.704	Up-regulation
AGC_PKC_PKCa_PRKCA_ST	P00533	EGFR	P17252	PRKCA	S1162	A1158P	1158	Missense	distal	-4	no	16.914	16.656	EPSD	COSMIC	16.704	Loss
AGC_PKC_PKCa_PRKCA_ST	Q8WTQ7	GRK7	P17252	PRKCA	S23	C25R	25	Missense	proximal	2	no	20.795	25.145	EPSD	COSMIC	16.704	Up-regulation
AGC_PKC_PKCa_PRKCA_ST	Q8WTQ7	GRK7	P17252	PRKCA	S23	P22S	22	Missense	proximal	-1	no	20.795	21.095	EPSD	COSMIC	16.704	Up-regulation
AGC_PKC_PKCa_PRKCA_ST	Q8WTQ7	GRK7	P17252	PRKCA	S23	K21E	21	Missense	proximal	-2	no	20.795	18.296	EPSD	COSMIC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	Q8WTQ7	GRK7	P17252	PRKCA	S23	A19T	19	Missense	distal	-4	no	20.795	20.046	EPSD	COSMIC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	Q8WTQ7	GRK7	P17252	PRKCA	S36	R33W	33	Missense	distal	-3	no	21.178	18.824	PhosphoSitePlus	COSMIC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	Q8WTQ7	GRK7	P17252	PRKCA	S36	R35H	35	Missense	proximal	-1	no	21.178	20.855	PhosphoSitePlus	COSMIC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	Q8WTQ7	GRK7	P17252	PRKCA	S36	S36I	36	Missense	central	0	yes	21.178	0.000	PhosphoSitePlus	COSMIC	16.704	Loss
AGC_PKC_PKCa_PRKCA_ST	Q8WTQ7	GRK7	P17252	PRKCA	S36	S36C	36	Missense	central	0	yes	21.178	0.000	PhosphoSitePlus	COSMIC	16.704	Loss
AGC_PKC_PKCa_PRKCA_ST	Q8WTQ7	GRK7	P17252	PRKCA	S36	G41V	41	Missense	distal	5	no	21.178	21.037	PhosphoSitePlus	COSMIC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	Q8WTQ7	GRK7	P17252	PRKCA	S36	P40F	40	Missense	distal	4	no	21.178	21.017	PhosphoSitePlus	COSMIC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	P02786	TFRC	P17252	PRKCA	S7	A5G	5	Missense	proximal	-2	no	17.729	17.942	EPSD	COSMIC	16.704	Up-regulation
AGC_PKC_PKCa_PRKCA_ST	P02786	TFRC	P17252	PRKCA	S7	F9S	9	Missense	proximal	2	no	17.729	17.412	EPSD	COSMIC;GDSC;CCLE	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	P02786	TFRC	P17252	PRKCA	S7	A8T	8	Missense	proximal	1	no	17.729	17.258	EPSD	COSMIC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	P02786	TFRC	P17252	PRKCA	S10	F9S	9	Missense	proximal	-1	no	16.478	17.185	EPSD	COSMIC;GDSC;CCLE	16.704	Gain
AGC_PKC_PKCa_PRKCA_ST	P02786	TFRC	P17252	PRKCA	S24	S19L	19	Missense	distal	-5	no	19.213	19.512	PhosphoSitePlus	COSMIC	16.704	Up-regulation
AGC_PKC_PKCa_PRKCA_ST	P02786	TFRC	P17252	PRKCA	S132	K130E	130	Missense	proximal	-2	no	21.336	18.838	EPSD	COSMIC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	P02786	TFRC	P17252	PRKCA	S132	D139H	139	Missense	distal	7	no	21.336	21.309	EPSD	COSMIC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	P02786	TFRC	P17252	PRKCA	S620	D624H	624	Missense	distal	4	no	16.807	17.123	EPSD	COSMIC	16.704	Up-regulation
AGC_PKC_PKCa_PRKCA_ST	P02786	TFRC	P17252	PRKCA	S620	V622L	622	Missense	proximal	2	no	16.807	16.834	EPSD	COSMIC	16.704	Up-regulation
AGC_PKC_PKCa_PRKCA_ST	P02786	TFRC	P17252	PRKCA	S620	N615S	615	Missense	distal	-5	no	16.807	16.736	EPSD	COSMIC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	P02786	TFRC	P17252	PRKCA	S654	R651C	651	Missense	distal	-3	no	16.775	14.035	EPSD	COSMIC	16.704	Loss
AGC_PKC_PKCa_PRKCA_ST	P02786	TFRC	P17252	PRKCA	S654	D648G	648	Missense	distal	-6	no	16.775	16.825	EPSD	COSMIC	16.704	Up-regulation
AGC_PKC_PKCa_PRKCA_ST	P02786	TFRC	P17252	PRKCA	S654	D659G	659	Missense	distal	5	no	16.775	16.855	EPSD	COSMIC	16.704	Up-regulation
AGC_PKC_PKCa_PRKCA_ST	P02786	TFRC	P17252	PRKCA	S654	S654P	654	Missense	central	0	yes	16.775	0.000	EPSD	COSMIC	16.704	Loss
AGC_PKC_PKCa_PRKCA_ST	P02786	TFRC	P17252	PRKCA	S691	L686V	686	Missense	distal	-5	no	17.785	17.349	EPSD	COSMIC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	P10721	KIT	P17252	PRKCA	S147	G153E	153	Missense	distal	6	no	17.343	17.386	EPSD	COSMIC	16.704	Up-regulation
AGC_PKC_PKCa_PRKCA_ST	P10721	KIT	P17252	PRKCA	S147	G153R	153	Missense	distal	6	no	17.343	17.493	EPSD	COSMIC	16.704	Up-regulation
AGC_PKC_PKCa_PRKCA_ST	P10721	KIT	P17252	PRKCA	S147	G150R	150	Missense	distal	3	no	17.343	17.983	EPSD	COSMIC	16.704	Up-regulation
AGC_PKC_PKCa_PRKCA_ST	P10721	KIT	P17252	PRKCA	S147	Q152L	152	Missense	distal	5	no	17.343	17.020	EPSD	COSMIC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	P10721	KIT	P17252	PRKCA	S147	S147F	147	Missense	central	0	yes	17.343	0.000	EPSD	COSMIC	16.704	Loss
AGC_PKC_PKCa_PRKCA_ST	P10721	KIT	P17252	PRKCA	S741	S746L	746	Missense	distal	5	no	22.542	22.352	PhosphoSitePlus;EPSD	COSMIC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	P10721	KIT	P17252	PRKCA	S741	I744L	744	Missense	distal	3	no	22.542	22.854	PhosphoSitePlus;EPSD	COSMIC	16.704	Up-regulation
AGC_PKC_PKCa_PRKCA_ST	P10721	KIT	P17252	PRKCA	S741	I748T	748	Missense	distal	7	no	22.542	22.702	PhosphoSitePlus;EPSD	COSMIC	16.704	Up-regulation
AGC_PKC_PKCa_PRKCA_ST	P10721	KIT	P17252	PRKCA	S741	G745V	745	Missense	distal	4	no	22.542	21.578	PhosphoSitePlus;EPSD	COSMIC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	P10721	KIT	P17252	PRKCA	S741	G745C	745	Missense	distal	4	no	22.542	21.745	PhosphoSitePlus;EPSD	COSMIC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	P10721	KIT	P17252	PRKCA	S741	K735M	735	Missense	distal	-6	no	22.542	22.473	PhosphoSitePlus;EPSD	COSMIC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	P10721	KIT	P17252	PRKCA	S746	S746L	746	Missense	central	0	yes	17.714	0.000	EPSD;PhosphoSitePlus	COSMIC	16.704	Loss
AGC_PKC_PKCa_PRKCA_ST	P10721	KIT	P17252	PRKCA	S746	I744L	744	Missense	proximal	-2	no	17.714	18.614	EPSD;PhosphoSitePlus	COSMIC	16.704	Up-regulation
AGC_PKC_PKCa_PRKCA_ST	P10721	KIT	P17252	PRKCA	S746	I748T	748	Missense	proximal	2	no	17.714	17.935	EPSD;PhosphoSitePlus	COSMIC	16.704	Up-regulation
AGC_PKC_PKCa_PRKCA_ST	P10721	KIT	P17252	PRKCA	S746	G745V	745	Missense	proximal	-1	no	17.714	16.003	EPSD;PhosphoSitePlus	COSMIC	16.704	Loss
AGC_PKC_PKCa_PRKCA_ST	P10721	KIT	P17252	PRKCA	S746	R750K	750	Missense	distal	4	no	17.714	17.885	EPSD;PhosphoSitePlus	COSMIC	16.704	Up-regulation
AGC_PKC_PKCa_PRKCA_ST	P10721	KIT	P17252	PRKCA	S746	G745C	745	Missense	proximal	-1	no	17.714	15.193	EPSD;PhosphoSitePlus	COSMIC	16.704	Loss
AGC_PKC_PKCa_PRKCA_ST	P10721	KIT	P17252	PRKCA	S891	R888W	888	Missense	distal	-3	no	17.821	15.467	EPSD	COSMIC	16.704	Loss
AGC_PKC_PKCa_PRKCA_ST	P10721	KIT	P17252	PRKCA	S891	E885K	885	Missense	distal	-6	no	17.821	17.888	EPSD	COSMIC;GDSC;CCLE	16.704	Up-regulation
AGC_PKC_PKCa_PRKCA_ST	P10721	KIT	P17252	PRKCA	S891	E898K	898	Missense	distal	7	no	17.821	17.967	EPSD	COSMIC	16.704	Up-regulation
AGC_PKC_PKCa_PRKCA_ST	Q9BR76	CORO1B	P17252	PRKCA	S2	R8W	8	Missense	distal	6	no	22.925	22.678	PhosphoSitePlus	COSMIC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	Q9BR76	CORO1B	P17252	PRKCA	S2	Q9H	9	Missense	distal	7	no	22.925	22.858	PhosphoSitePlus	COSMIC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	Q9BR76	CORO1B	P17252	PRKCA	S2	R4H	4	Missense	proximal	2	no	22.925	17.902	PhosphoSitePlus	COSMIC;GDSC;CCLE	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	Q9BR76	CORO1B	P17252	PRKCA	S407	R402W	402	Missense	distal	-5	no	17.036	16.723	EPSD	COSMIC;GDSC;CCLE	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	Q9BR76	CORO1B	P17252	PRKCA	S407	R409H	409	Missense	proximal	2	no	17.036	12.013	EPSD	COSMIC;CCLE	16.704	Loss
AGC_PKC_PKCa_PRKCA_ST	Q9BR76	CORO1B	P17252	PRKCA	S407	V411M	411	Missense	distal	4	no	17.036	18.408	EPSD	COSMIC	16.704	Up-regulation
AGC_PKC_PKCa_PRKCA_ST	Q9BR76	CORO1B	P17252	PRKCA	S407	S407N	407	Missense	central	0	yes	17.036	0.000	EPSD	COSMIC;CCLE	16.704	Loss
AGC_PKC_PKCa_PRKCA_ST	Q13131	PRKAA1	P17252	PRKCA	S197	I196M	196	Missense	proximal	-1	no	15.962	17.905	EPSD	COSMIC	16.704	Gain
AGC_PKC_PKCa_PRKCA_ST	Q13131	PRKAA1	P17252	PRKCA	S496	V497A	497	Missense	proximal	1	no	17.709	17.555	PhosphoSitePlus	COSMIC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	Q13131	PRKAA1	P17252	PRKCA	S496	R501G	501	Missense	distal	5	no	17.709	17.427	PhosphoSitePlus	COSMIC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	O60928	KCNJ13	P17252	PRKCA	S201	R203Q	203	Missense	proximal	2	no	19.346	15.512	PhosphoSitePlus	COSMIC	16.704	Loss
AGC_PKC_PKCa_PRKCA_ST	O60928	KCNJ13	P17252	PRKCA	S201	L199V	199	Missense	proximal	-2	no	19.346	19.192	PhosphoSitePlus	COSMIC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	O60928	KCNJ13	P17252	PRKCA	S287	R284K	284	Missense	distal	-3	no	19.566	17.540	EPSD	COSMIC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	Q13976	PRKG1	P17252	PRKCA	S27	K20E	20	Missense	distal	-7	no	23.289	23.281	EPSD	COSMIC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	Q13976	PRKG1	P17252	PRKCA	S273	E271V	271	Missense	proximal	-2	no	15.642	16.926	EPSD	COSMIC	16.704	Gain
AGC_PKC_PKCa_PRKCA_ST	P01116	KRAS	P17252	PRKCA	S39	E37K	37	Missense	proximal	-2	no	15.627	18.126	EPSD	COSMIC	16.704	Gain
AGC_PKC_PKCa_PRKCA_ST	P01116	KRAS	P17252	PRKCA	S136	G138R	138	Missense	proximal	2	no	11.594	16.840	EPSD	COSMIC	16.704	Gain
AGC_PKC_PKCa_PRKCA_ST	O75376	NCOR1	P17252	PRKCA	S2	S3T	3	Missense	proximal	1	no	16.545	16.872	EPSD	COSMIC	16.704	Gain
AGC_PKC_PKCa_PRKCA_ST	O75376	NCOR1	P17252	PRKCA	S70	E74K	74	Missense	distal	4	no	21.046	21.585	PhosphoSitePlus	COSMIC	16.704	Up-regulation
AGC_PKC_PKCa_PRKCA_ST	O75376	NCOR1	P17252	PRKCA	S88	R81Q	81	Missense	distal	-7	no	17.988	17.980	EPSD	COSMIC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	O75376	NCOR1	P17252	PRKCA	S88	R85T	85	Missense	distal	-3	no	17.988	13.825	EPSD	COSMIC	16.704	Loss
AGC_PKC_PKCa_PRKCA_ST	O75376	NCOR1	P17252	PRKCA	S88	S88G	88	Missense	central	0	yes	17.988	0.000	EPSD	COSMIC	16.704	Loss
AGC_PKC_PKCa_PRKCA_ST	O75376	NCOR1	P17252	PRKCA	S88	E90G	90	Missense	proximal	2	no	17.988	18.443	EPSD	COSMIC	16.704	Up-regulation
AGC_PKC_PKCa_PRKCA_ST	O75376	NCOR1	P17252	PRKCA	S88	H93Y	93	Missense	distal	5	no	17.988	18.133	EPSD	COSMIC	16.704	Up-regulation
AGC_PKC_PKCa_PRKCA_ST	O75376	NCOR1	P17252	PRKCA	S88	S88R	88	Missense	central	0	yes	17.988	0.000	EPSD	COSMIC	16.704	Loss
AGC_PKC_PKCa_PRKCA_ST	O75376	NCOR1	P17252	PRKCA	S106	D100N	100	Missense	distal	-6	no	20.474	20.501	EPSD	COSMIC	16.704	Up-regulation
AGC_PKC_PKCa_PRKCA_ST	O75376	NCOR1	P17252	PRKCA	S401	L400I	400	Missense	proximal	-1	no	19.239	18.376	EPSD	COSMIC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	O75376	NCOR1	P17252	PRKCA	S401	E394D	394	Missense	distal	-7	no	19.239	19.243	EPSD	COSMIC	16.704	Up-regulation
AGC_PKC_PKCa_PRKCA_ST	O75376	NCOR1	P17252	PRKCA	T568	A567V	567	Missense	proximal	-1	no	18.285	17.382	EPSD	COSMIC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	O75376	NCOR1	P17252	PRKCA	T568	R570W	570	Missense	proximal	2	no	18.285	12.845	EPSD	COSMIC	16.704	Loss
AGC_PKC_PKCa_PRKCA_ST	O75376	NCOR1	P17252	PRKCA	T568	Q566L	566	Missense	proximal	-2	no	18.285	17.356	EPSD	COSMIC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	O75376	NCOR1	P17252	PRKCA	T568	T574I	574	Missense	distal	6	no	18.285	18.299	EPSD	COSMIC	16.704	Up-regulation
AGC_PKC_PKCa_PRKCA_ST	O75376	NCOR1	P17252	PRKCA	T568	A575V	575	Missense	distal	7	no	18.285	18.231	EPSD	COSMIC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	O75376	NCOR1	P17252	PRKCA	S990	S990Y	990	Missense	central	0	yes	17.717	0.000	EPSD	COSMIC	16.704	Loss
AGC_PKC_PKCa_PRKCA_ST	O75376	NCOR1	P17252	PRKCA	S990	R988I	988	Missense	proximal	-2	no	17.717	14.129	EPSD	COSMIC	16.704	Loss
AGC_PKC_PKCa_PRKCA_ST	O75376	NCOR1	P17252	PRKCA	S990	C994Y	994	Missense	distal	4	no	17.717	18.475	EPSD	COSMIC	16.704	Up-regulation
AGC_PKC_PKCa_PRKCA_ST	O75376	NCOR1	P17252	PRKCA	S1111	E1109Q	1109	Missense	proximal	-2	no	17.357	19.725	EPSD	COSMIC	16.704	Up-regulation
AGC_PKC_PKCa_PRKCA_ST	O75376	NCOR1	P17252	PRKCA	S1111	S1117L	1117	Missense	distal	6	no	17.357	17.346	EPSD	COSMIC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	O75376	NCOR1	P17252	PRKCA	S1111	K1106N	1106	Missense	distal	-5	no	17.357	17.014	EPSD	COSMIC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	O75376	NCOR1	P17252	PRKCA	S1111	E1109K	1109	Missense	proximal	-2	no	17.357	19.856	EPSD	COSMIC	16.704	Up-regulation
AGC_PKC_PKCa_PRKCA_ST	O75376	NCOR1	P17252	PRKCA	S1111	S1117T	1117	Missense	distal	6	no	17.357	17.309	EPSD	COSMIC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	O75376	NCOR1	P17252	PRKCA	S1111	F1110V	1110	Missense	proximal	-1	no	17.357	16.602	EPSD	COSMIC;CCLE	16.704	Loss
AGC_PKC_PKCa_PRKCA_ST	O75376	NCOR1	P17252	PRKCA	S1111	R1113Q	1113	Missense	proximal	2	no	17.357	13.523	EPSD	COSMIC	16.704	Loss
AGC_PKC_PKCa_PRKCA_ST	O75376	NCOR1	P17252	PRKCA	S1160	G1163D	1163	Missense	distal	3	no	19.776	18.690	EPSD	COSMIC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	O75376	NCOR1	P17252	PRKCA	S1160	S1160F	1160	Missense	central	0	yes	19.776	0.000	EPSD	COSMIC	16.704	Loss
AGC_PKC_PKCa_PRKCA_ST	O75376	NCOR1	P17252	PRKCA	S1160	S1164L	1164	Missense	distal	4	no	19.776	18.983	EPSD	COSMIC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	O75376	NCOR1	P17252	PRKCA	S1160	R1162Q	1162	Missense	proximal	2	no	19.776	15.942	EPSD	COSMIC	16.704	Loss
AGC_PKC_PKCa_PRKCA_ST	O75376	NCOR1	P17252	PRKCA	S1160	S1157N	1157	Missense	distal	-3	no	19.776	18.419	EPSD	COSMIC;CCLE	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	O75376	NCOR1	P17252	PRKCA	S1160	V1155M	1155	Missense	distal	-5	no	19.776	20.173	EPSD	COSMIC	16.704	Up-regulation
AGC_PKC_PKCa_PRKCA_ST	O75376	NCOR1	P17252	PRKCA	S1160	S1154P	1154	Missense	distal	-6	no	19.776	19.744	EPSD	COSMIC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	O75376	NCOR1	P17252	PRKCA	S1186	S1188L	1188	Missense	proximal	2	no	18.612	18.244	EPSD	COSMIC;GDSC;CCLE	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	O75376	NCOR1	P17252	PRKCA	S1186	T1179I	1179	Missense	distal	-7	no	18.612	18.605	EPSD	COSMIC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	O75376	NCOR1	P17252	PRKCA	S1186	P1191L	1191	Missense	distal	5	no	18.612	18.262	EPSD	COSMIC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	O75376	NCOR1	P17252	PRKCA	S1186	L1182S	1182	Missense	distal	-4	no	18.612	19.043	EPSD	COSMIC	16.704	Up-regulation
AGC_PKC_PKCa_PRKCA_ST	O75376	NCOR1	P17252	PRKCA	S1234	R1233Q	1233	Missense	proximal	-1	no	19.627	18.810	EPSD	COSMIC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	O75376	NCOR1	P17252	PRKCA	S1234	R1229Q	1229	Missense	distal	-5	no	19.627	19.475	EPSD	COSMIC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	O75376	NCOR1	P17252	PRKCA	S1242	L1243F	1243	Missense	proximal	1	no	17.676	18.333	EPSD	COSMIC	16.704	Up-regulation
AGC_PKC_PKCa_PRKCA_ST	O75376	NCOR1	P17252	PRKCA	S1242	S1242G	1242	Missense	central	0	yes	17.676	0.000	EPSD	COSMIC	16.704	Loss
AGC_PKC_PKCa_PRKCA_ST	O75376	NCOR1	P17252	PRKCA	S1259	G1257R	1257	Missense	proximal	-2	no	20.302	23.174	EPSD	COSMIC	16.704	Up-regulation
AGC_PKC_PKCa_PRKCA_ST	O75376	NCOR1	P17252	PRKCA	S1259	G1257V	1257	Missense	proximal	-2	no	20.302	20.332	EPSD	COSMIC	16.704	Up-regulation
AGC_PKC_PKCa_PRKCA_ST	O75376	NCOR1	P17252	PRKCA	S1259	P1264S	1264	Missense	distal	5	no	20.302	20.143	EPSD	COSMIC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	O75376	NCOR1	P17252	PRKCA	S1259	V1265A	1265	Missense	distal	6	no	20.302	20.421	EPSD	COSMIC	16.704	Up-regulation
AGC_PKC_PKCa_PRKCA_ST	O75376	NCOR1	P17252	PRKCA	S1259	Q1256H	1256	Missense	distal	-3	no	20.302	19.303	EPSD	COSMIC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	O75376	NCOR1	P17252	PRKCA	S1263	G1257R	1257	Missense	distal	-6	no	18.160	18.267	EPSD	COSMIC	16.704	Up-regulation
AGC_PKC_PKCa_PRKCA_ST	O75376	NCOR1	P17252	PRKCA	S1263	G1257V	1257	Missense	distal	-6	no	18.160	18.081	EPSD	COSMIC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	O75376	NCOR1	P17252	PRKCA	S1263	P1264S	1264	Missense	proximal	1	no	18.160	17.761	EPSD	COSMIC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	O75376	NCOR1	P17252	PRKCA	S1263	V1265A	1265	Missense	proximal	2	no	18.160	18.476	EPSD	COSMIC	16.704	Up-regulation
AGC_PKC_PKCa_PRKCA_ST	O75376	NCOR1	P17252	PRKCA	S1263	Q1256H	1256	Missense	distal	-7	no	18.160	18.162	EPSD	COSMIC	16.704	Up-regulation
AGC_PKC_PKCa_PRKCA_ST	O75376	NCOR1	P17252	PRKCA	T1300	M1297T	1297	Missense	distal	-3	no	17.771	16.579	EPSD	COSMIC	16.704	Loss
AGC_PKC_PKCa_PRKCA_ST	O75376	NCOR1	P17252	PRKCA	T1300	G1299V	1299	Missense	proximal	-1	no	17.771	16.060	EPSD	COSMIC	16.704	Loss
AGC_PKC_PKCa_PRKCA_ST	O75376	NCOR1	P17252	PRKCA	T1300	R1302T	1302	Missense	proximal	2	no	17.771	12.960	EPSD	COSMIC	16.704	Loss
AGC_PKC_PKCa_PRKCA_ST	O75376	NCOR1	P17252	PRKCA	S1322	P1323S	1323	Missense	proximal	1	no	17.249	16.850	EPSD	COSMIC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	O75376	NCOR1	P17252	PRKCA	S1322	Q1317K	1317	Missense	distal	-5	no	17.249	17.388	EPSD	COSMIC	16.704	Up-regulation
AGC_PKC_PKCa_PRKCA_ST	O75376	NCOR1	P17252	PRKCA	S1322	P1315S	1315	Missense	distal	-7	no	17.249	17.252	EPSD	COSMIC	16.704	Up-regulation
AGC_PKC_PKCa_PRKCA_ST	O75376	NCOR1	P17252	PRKCA	S1364	V1371F	1371	Missense	distal	7	no	18.060	18.053	EPSD	COSMIC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	O75376	NCOR1	P17252	PRKCA	S1364	R1365C	1365	Missense	proximal	1	no	18.060	15.224	EPSD	COSMIC	16.704	Loss
AGC_PKC_PKCa_PRKCA_ST	O75376	NCOR1	P17252	PRKCA	S1364	I1359M	1359	Missense	distal	-5	no	18.060	18.465	EPSD	COSMIC	16.704	Up-regulation
AGC_PKC_PKCa_PRKCA_ST	O75376	NCOR1	P17252	PRKCA	S1364	R1365Q	1365	Missense	proximal	1	no	18.060	17.943	EPSD	COSMIC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	O75376	NCOR1	P17252	PRKCA	S1364	V1371A	1371	Missense	distal	7	no	18.060	18.115	EPSD	COSMIC	16.704	Up-regulation
AGC_PKC_PKCa_PRKCA_ST	O75376	NCOR1	P17252	PRKCA	S1364	T1361S	1361	Missense	distal	-3	no	18.060	19.353	EPSD	COSMIC;GDSC;CCLE	16.704	Up-regulation
AGC_PKC_PKCa_PRKCA_ST	O75376	NCOR1	P17252	PRKCA	S1414	G1416R	1416	Missense	proximal	2	no	15.446	20.692	EPSD	COSMIC	16.704	Gain
AGC_PKC_PKCa_PRKCA_ST	O75376	NCOR1	P17252	PRKCA	T1443	T1449M	1449	Missense	distal	6	no	16.827	16.875	EPSD	COSMIC	16.704	Up-regulation
AGC_PKC_PKCa_PRKCA_ST	O75376	NCOR1	P17252	PRKCA	T1443	S1450L	1450	Missense	distal	7	no	16.827	16.830	EPSD	COSMIC	16.704	Up-regulation
AGC_PKC_PKCa_PRKCA_ST	O75376	NCOR1	P17252	PRKCA	T1443	V1444A	1444	Missense	proximal	1	no	16.827	16.674	EPSD	COSMIC;GDSC;CCLE	16.704	Loss
AGC_PKC_PKCa_PRKCA_ST	O75376	NCOR1	P17252	PRKCA	T1443	D1437Y	1437	Missense	distal	-6	no	16.827	16.858	EPSD	COSMIC	16.704	Up-regulation
AGC_PKC_PKCa_PRKCA_ST	O75376	NCOR1	P17252	PRKCA	T1443	R1447W	1447	Missense	distal	4	no	16.827	15.291	EPSD	COSMIC	16.704	Loss
AGC_PKC_PKCa_PRKCA_ST	O75376	NCOR1	P17252	PRKCA	S1480	I1475F	1475	Missense	distal	-5	no	17.271	17.519	EPSD	COSMIC	16.704	Up-regulation
AGC_PKC_PKCa_PRKCA_ST	O75376	NCOR1	P17252	PRKCA	S1480	A1481E	1481	Missense	proximal	1	no	17.271	16.080	EPSD	COSMIC	16.704	Loss
AGC_PKC_PKCa_PRKCA_ST	O75376	NCOR1	P17252	PRKCA	S1480	G1474W	1474	Missense	distal	-6	no	17.271	17.094	EPSD	COSMIC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	O75376	NCOR1	P17252	PRKCA	S1480	I1475M	1475	Missense	distal	-5	no	17.271	17.676	EPSD	COSMIC	16.704	Up-regulation
AGC_PKC_PKCa_PRKCA_ST	O75376	NCOR1	P17252	PRKCA	S1496	S1503N	1503	Missense	distal	7	no	18.642	18.618	EPSD	COSMIC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	O75376	NCOR1	P17252	PRKCA	S1496	M1499T	1499	Missense	distal	3	no	18.642	18.073	EPSD	COSMIC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	O75376	NCOR1	P17252	PRKCA	S1496	M1492I	1492	Missense	distal	-4	no	18.642	17.927	EPSD	COSMIC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	O75376	NCOR1	P17252	PRKCA	S1496	Q1489E	1489	Missense	distal	-7	no	18.642	18.637	EPSD	COSMIC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	O75376	NCOR1	P17252	PRKCA	S1496	M1499I	1499	Missense	distal	3	no	18.642	17.361	EPSD	COSMIC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	O75376	NCOR1	P17252	PRKCA	S1496	N1490S	1490	Missense	distal	-6	no	18.642	18.699	EPSD	COSMIC	16.704	Up-regulation
AGC_PKC_PKCa_PRKCA_ST	O75376	NCOR1	P17252	PRKCA	S1528	P1534S	1534	Missense	distal	6	no	18.458	18.425	EPSD	COSMIC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	O75376	NCOR1	P17252	PRKCA	S1554	R1561W	1561	Missense	distal	7	no	16.797	16.616	EPSD	COSMIC	16.704	Loss
AGC_PKC_PKCa_PRKCA_ST	O75376	NCOR1	P17252	PRKCA	S1554	G1553A	1553	Missense	proximal	-1	no	16.797	15.989	EPSD	COSMIC	16.704	Loss
AGC_PKC_PKCa_PRKCA_ST	O75376	NCOR1	P17252	PRKCA	S1636	P1641L	1641	Missense	distal	5	no	21.557	21.207	EPSD	COSMIC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	O75376	NCOR1	P17252	PRKCA	S1636	G1643S	1643	Missense	distal	7	no	21.557	21.535	EPSD	COSMIC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	O75376	NCOR1	P17252	PRKCA	S1636	G1634E	1634	Missense	proximal	-2	no	21.557	20.303	EPSD	COSMIC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	O75376	NCOR1	P17252	PRKCA	S1695	S1697Y	1697	Missense	proximal	2	no	16.938	17.062	EPSD	COSMIC	16.704	Up-regulation
AGC_PKC_PKCa_PRKCA_ST	O75376	NCOR1	P17252	PRKCA	S1695	S1699F	1699	Missense	distal	4	no	16.938	16.576	EPSD	COSMIC;GDSC;CCLE	16.704	Loss
AGC_PKC_PKCa_PRKCA_ST	O75376	NCOR1	P17252	PRKCA	S1695	P1689T	1689	Missense	distal	-6	no	16.938	16.844	EPSD	COSMIC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	O75376	NCOR1	P17252	PRKCA	S1695	P1700A	1700	Missense	distal	5	no	16.938	16.881	EPSD	COSMIC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	O75376	NCOR1	P17252	PRKCA	S1695	P1689S	1689	Missense	distal	-6	no	16.938	16.969	EPSD	COSMIC	16.704	Up-regulation
AGC_PKC_PKCa_PRKCA_ST	O75376	NCOR1	P17252	PRKCA	S1695	P1700Q	1700	Missense	distal	5	no	16.938	16.911	EPSD	COSMIC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	O75376	NCOR1	P17252	PRKCA	S1695	A1696P	1696	Missense	proximal	1	no	16.938	16.539	EPSD	COSMIC;GDSC	16.704	Loss
AGC_PKC_PKCa_PRKCA_ST	O75376	NCOR1	P17252	PRKCA	S1695	P1692T	1692	Missense	distal	-3	no	16.938	16.623	EPSD	COSMIC	16.704	Loss
AGC_PKC_PKCa_PRKCA_ST	O75376	NCOR1	P17252	PRKCA	S1742	R1747Q	1747	Missense	distal	5	no	17.305	17.296	EPSD	COSMIC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	O75376	NCOR1	P17252	PRKCA	S1742	P1740T	1740	Missense	proximal	-2	no	17.305	17.453	EPSD	COSMIC	16.704	Up-regulation
AGC_PKC_PKCa_PRKCA_ST	O75376	NCOR1	P17252	PRKCA	S1742	D1735N	1735	Missense	distal	-7	no	17.305	17.304	EPSD	COSMIC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	O75376	NCOR1	P17252	PRKCA	S1742	S1742L	1742	Missense	central	0	yes	17.305	0.000	EPSD	COSMIC	16.704	Loss
AGC_PKC_PKCa_PRKCA_ST	O75376	NCOR1	P17252	PRKCA	S1760	S1758L	1758	Missense	proximal	-2	no	17.669	18.283	EPSD	COSMIC	16.704	Up-regulation
AGC_PKC_PKCa_PRKCA_ST	O75376	NCOR1	P17252	PRKCA	S1760	R1755H	1755	Missense	distal	-5	no	17.669	17.313	EPSD	COSMIC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	O75376	NCOR1	P17252	PRKCA	S1760	S1758P	1758	Missense	proximal	-2	no	17.669	17.928	EPSD	COSMIC	16.704	Up-regulation
AGC_PKC_PKCa_PRKCA_ST	O75376	NCOR1	P17252	PRKCA	S1760	P1757S	1757	Missense	distal	-3	no	17.669	18.647	EPSD	COSMIC	16.704	Up-regulation
AGC_PKC_PKCa_PRKCA_ST	O75376	NCOR1	P17252	PRKCA	S1760	V1761I	1761	Missense	proximal	1	no	17.669	18.380	EPSD	COSMIC	16.704	Up-regulation
AGC_PKC_PKCa_PRKCA_ST	O75376	NCOR1	P17252	PRKCA	S1963	R1965S	1965	Missense	proximal	2	no	17.446	12.826	EPSD	COSMIC	16.704	Loss
AGC_PKC_PKCa_PRKCA_ST	O75376	NCOR1	P17252	PRKCA	S1963	D1956V	1956	Missense	distal	-7	no	17.446	17.442	EPSD	COSMIC;GDSC;CCLE	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	O75376	NCOR1	P17252	PRKCA	S2023	R2018T	2018	Missense	distal	-5	no	16.886	16.787	EPSD	COSMIC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	O75376	NCOR1	P17252	PRKCA	S2023	H2016N	2016	Missense	distal	-7	no	16.886	16.883	EPSD	COSMIC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	O75376	NCOR1	P17252	PRKCA	S2023	Y2017C	2017	Missense	distal	-6	no	16.886	16.644	EPSD	COSMIC;CCLE	16.704	Loss
AGC_PKC_PKCa_PRKCA_ST	O75376	NCOR1	P17252	PRKCA	S2023	R2018Q	2018	Missense	distal	-5	no	16.886	16.734	EPSD	COSMIC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	O75376	NCOR1	P17252	PRKCA	S2023	S2025F	2025	Missense	proximal	2	no	16.886	17.203	EPSD	COSMIC	16.704	Up-regulation
AGC_PKC_PKCa_PRKCA_ST	O75376	NCOR1	P17252	PRKCA	S2098	E2104K	2104	Missense	distal	6	no	17.497	17.591	EPSD	COSMIC	16.704	Up-regulation
AGC_PKC_PKCa_PRKCA_ST	O75376	NCOR1	P17252	PRKCA	S2098	R2100H	2100	Missense	proximal	2	no	17.497	12.473	EPSD	COSMIC	16.704	Loss
AGC_PKC_PKCa_PRKCA_ST	O75376	NCOR1	P17252	PRKCA	S2098	T2091A	2091	Missense	distal	-7	no	17.497	17.502	EPSD	COSMIC	16.704	Up-regulation
AGC_PKC_PKCa_PRKCA_ST	O75376	NCOR1	P17252	PRKCA	S2098	N2099H	2099	Missense	proximal	1	no	17.497	17.811	EPSD	COSMIC	16.704	Up-regulation
AGC_PKC_PKCa_PRKCA_ST	O75376	NCOR1	P17252	PRKCA	S2102	E2104K	2104	Missense	proximal	2	no	15.104	20.384	EPSD	COSMIC	16.704	Gain
AGC_PKC_PKCa_PRKCA_ST	O75376	NCOR1	P17252	PRKCA	S2117	R2118C	2118	Missense	proximal	1	no	17.620	14.784	EPSD	COSMIC	16.704	Loss
AGC_PKC_PKCa_PRKCA_ST	O75376	NCOR1	P17252	PRKCA	S2117	L2124V	2124	Missense	distal	7	no	17.620	17.560	EPSD	COSMIC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	O75376	NCOR1	P17252	PRKCA	S2117	H2111L	2111	Missense	distal	-6	no	17.620	17.549	EPSD	COSMIC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	O75376	NCOR1	P17252	PRKCA	S2117	Q2113E	2113	Missense	distal	-4	no	17.620	17.301	EPSD	COSMIC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	O75376	NCOR1	P17252	PRKCA	S2117	L2124I	2124	Missense	distal	7	no	17.620	17.464	EPSD	COSMIC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	O75376	NCOR1	P17252	PRKCA	S2117	H2112N	2112	Missense	distal	-5	no	17.620	17.619	EPSD	COSMIC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	O75376	NCOR1	P17252	PRKCA	S2131	P2133S	2133	Missense	proximal	2	no	18.522	19.104	EPSD	COSMIC;GDSC;CCLE	16.704	Up-regulation
AGC_PKC_PKCa_PRKCA_ST	O75376	NCOR1	P17252	PRKCA	S2131	L2124V	2124	Missense	distal	-7	no	18.522	18.519	EPSD	COSMIC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	O75376	NCOR1	P17252	PRKCA	S2131	E2138K	2138	Missense	distal	7	no	18.522	18.667	EPSD	COSMIC	16.704	Up-regulation
AGC_PKC_PKCa_PRKCA_ST	O75376	NCOR1	P17252	PRKCA	S2131	L2124I	2124	Missense	distal	-7	no	18.522	18.518	EPSD	COSMIC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	O75376	NCOR1	P17252	PRKCA	S2136	E2138K	2138	Missense	proximal	2	no	15.476	20.755	EPSD	COSMIC	16.704	Gain
AGC_PKC_PKCa_PRKCA_ST	O75376	NCOR1	P17252	PRKCA	S2140	E2138K	2138	Missense	proximal	-2	no	14.300	16.799	EPSD	COSMIC	16.704	Gain
AGC_PKC_PKCa_PRKCA_ST	O75376	NCOR1	P17252	PRKCA	S2253	P2257H	2257	Missense	distal	4	no	19.056	19.220	EPSD	COSMIC	16.704	Up-regulation
AGC_PKC_PKCa_PRKCA_ST	O75376	NCOR1	P17252	PRKCA	S2253	S2246L	2246	Missense	distal	-7	no	19.056	19.050	EPSD	COSMIC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	O75376	NCOR1	P17252	PRKCA	S2253	S2253Y	2253	Missense	central	0	yes	19.056	0.000	EPSD	COSMIC;GDSC;CCLE	16.704	Loss
AGC_PKC_PKCa_PRKCA_ST	O75376	NCOR1	P17252	PRKCA	S2330	I2327M	2327	Missense	distal	-3	no	15.501	17.016	EPSD	COSMIC	16.704	Gain
AGC_PKC_PKCa_PRKCA_ST	O75376	NCOR1	P17252	PRKCA	S2335	S2332L	2332	Missense	distal	-3	no	17.167	15.682	EPSD	COSMIC	16.704	Loss
AGC_PKC_PKCa_PRKCA_ST	O75376	NCOR1	P17252	PRKCA	S2335	P2340H	2340	Missense	distal	5	no	17.167	16.890	EPSD	COSMIC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	O75376	NCOR1	P17252	PRKCA	S2335	K2336Q	2336	Missense	proximal	1	no	17.167	17.013	EPSD	COSMIC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	O75376	NCOR1	P17252	PRKCA	S2335	S2337F	2337	Missense	proximal	2	no	17.167	17.484	EPSD	COSMIC	16.704	Up-regulation
AGC_PKC_PKCa_PRKCA_ST	O75376	NCOR1	P17252	PRKCA	T2347	E2348K	2348	Missense	proximal	1	no	16.214	17.818	EPSD	COSMIC	16.704	Gain
AGC_PKC_PKCa_PRKCA_ST	O75376	NCOR1	P17252	PRKCA	S2394	P2387S	2387	Missense	distal	-7	no	18.118	18.121	EPSD	COSMIC	16.704	Up-regulation
AGC_PKC_PKCa_PRKCA_ST	O75376	NCOR1	P17252	PRKCA	S2394	T2396S	2396	Missense	proximal	2	no	18.118	18.308	EPSD	COSMIC	16.704	Up-regulation
AGC_PKC_PKCa_PRKCA_ST	O75376	NCOR1	P17252	PRKCA	S2394	R2391W	2391	Missense	distal	-3	no	18.118	15.764	EPSD	COSMIC	16.704	Loss
AGC_PKC_PKCa_PRKCA_ST	Q9UQ13	SHOC2	P17252	PRKCA	S2	L5F	5	Missense	distal	3	no	17.809	18.143	EPSD	COSMIC	16.704	Up-regulation
AGC_PKC_PKCa_PRKCA_ST	Q9UQ13	SHOC2	P17252	PRKCA	S2	S2G	2	Missense	central	0	yes	17.809	0.000	EPSD	COSMIC	16.704	Loss
AGC_PKC_PKCa_PRKCA_ST	Q9UQ13	SHOC2	P17252	PRKCA	S3	D10N	10	Missense	distal	7	no	17.707	17.681	EPSD	COSMIC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	Q9UQ13	SHOC2	P17252	PRKCA	S3	L5F	5	Missense	proximal	2	no	17.707	18.391	EPSD	COSMIC	16.704	Up-regulation
AGC_PKC_PKCa_PRKCA_ST	Q9UQ13	SHOC2	P17252	PRKCA	S3	S2G	2	Missense	proximal	-1	no	17.707	17.955	EPSD	COSMIC	16.704	Up-regulation
AGC_PKC_PKCa_PRKCA_ST	Q9UQ13	SHOC2	P17252	PRKCA	S4	L5F	5	Missense	proximal	1	no	16.356	17.014	EPSD	COSMIC	16.704	Gain
AGC_PKC_PKCa_PRKCA_ST	Q9UQ13	SHOC2	P17252	PRKCA	S4	S2G	2	Missense	proximal	-2	no	16.356	16.786	EPSD	COSMIC	16.704	Gain
AGC_PKC_PKCa_PRKCA_ST	Q9UQ13	SHOC2	P17252	PRKCA	S11	D10N	10	Missense	proximal	-1	no	16.441	16.778	EPSD	COSMIC	16.704	Gain
AGC_PKC_PKCa_PRKCA_ST	Q9UQ13	SHOC2	P17252	PRKCA	S85	K83Q	83	Missense	proximal	-2	no	17.159	17.028	EPSD	COSMIC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	Q9UQ13	SHOC2	P17252	PRKCA	S118	P116L	116	Missense	proximal	-2	no	18.427	18.781	EPSD	COSMIC	16.704	Up-regulation
AGC_PKC_PKCa_PRKCA_ST	Q9UQ13	SHOC2	P17252	PRKCA	S221	R223Q	223	Missense	proximal	2	no	22.884	19.050	EPSD	COSMIC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	Q9UQ13	SHOC2	P17252	PRKCA	S297	P300H	300	Missense	distal	3	no	17.386	18.205	PhosphoSitePlus;EPSD	COSMIC	16.704	Up-regulation
AGC_PKC_PKCa_PRKCA_ST	Q9UQ13	SHOC2	P17252	PRKCA	S297	P300S	300	Missense	distal	3	no	17.386	17.526	PhosphoSitePlus;EPSD	COSMIC	16.704	Up-regulation
AGC_PKC_PKCa_PRKCA_ST	Q9UQ13	SHOC2	P17252	PRKCA	S297	A298T	298	Missense	proximal	1	no	17.386	16.915	PhosphoSitePlus;EPSD	COSMIC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	P29350	PTPN6	P17252	PRKCA	S10	R7Q	7	Missense	distal	-3	no	18.049	15.191	EPSD	COSMIC	16.704	Loss
AGC_PKC_PKCa_PRKCA_ST	P29350	PTPN6	P17252	PRKCA	S10	T16I	16	Missense	distal	6	no	18.049	18.063	EPSD	COSMIC	16.704	Up-regulation
AGC_PKC_PKCa_PRKCA_ST	P29350	PTPN6	P17252	PRKCA	S10	D13Y	13	Missense	distal	3	no	18.049	17.506	EPSD	COSMIC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	P29350	PTPN6	P17252	PRKCA	S10	F5L	5	Missense	distal	-5	no	18.049	18.245	EPSD	COSMIC	16.704	Up-regulation
AGC_PKC_PKCa_PRKCA_ST	P29350	PTPN6	P17252	PRKCA	S10	D8Y	8	Missense	proximal	-2	no	18.049	18.739	EPSD	COSMIC;GDSC;CCLE	16.704	Up-regulation
AGC_PKC_PKCa_PRKCA_ST	P29350	PTPN6	P17252	PRKCA	S10	L17M	17	Missense	distal	7	no	18.049	18.057	EPSD	COSMIC	16.704	Up-regulation
AGC_PKC_PKCa_PRKCA_ST	P29350	PTPN6	P17252	PRKCA	S32	G25C	25	Missense	distal	-7	no	20.658	20.648	EPSD	COSMIC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	P29350	PTPN6	P17252	PRKCA	S32	R33G	33	Missense	proximal	1	no	20.658	19.705	EPSD	COSMIC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	P29350	PTPN6	P17252	PRKCA	S32	R30W	30	Missense	proximal	-2	no	20.658	18.661	EPSD	COSMIC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	P29350	PTPN6	P17252	PRKCA	S32	S32N	32	Missense	central	0	yes	20.658	0.000	EPSD	COSMIC	16.704	Loss
AGC_PKC_PKCa_PRKCA_ST	P29350	PTPN6	P17252	PRKCA	S528	E535G	535	Missense	distal	7	no	20.008	20.079	EPSD	COSMIC	16.704	Up-regulation
AGC_PKC_PKCa_PRKCA_ST	P29350	PTPN6	P17252	PRKCA	S528	S528L	528	Missense	central	0	yes	20.008	0.000	EPSD	COSMIC	16.704	Loss
AGC_PKC_PKCa_PRKCA_ST	P29350	PTPN6	P17252	PRKCA	S528	S528P	528	Missense	central	0	yes	20.008	0.000	EPSD	COSMIC	16.704	Loss
AGC_PKC_PKCa_PRKCA_ST	P29350	PTPN6	P17252	PRKCA	S528	L523V	523	Missense	distal	-5	no	20.008	19.572	EPSD	COSMIC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	P29350	PTPN6	P17252	PRKCA	S556	R554S	554	Missense	proximal	-2	no	21.149	17.847	EPSD	COSMIC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	P29350	PTPN6	P17252	PRKCA	S556	R554C	554	Missense	proximal	-2	no	21.149	19.449	EPSD	COSMIC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	P29350	PTPN6	P17252	PRKCA	S556	R554H	554	Missense	proximal	-2	no	21.149	16.595	EPSD	COSMIC;GDSC	16.704	Loss
AGC_PKC_PKCa_PRKCA_ST	P29350	PTPN6	P17252	PRKCA	S557	R554S	554	Missense	distal	-3	no	18.262	15.392	EPSD	COSMIC	16.704	Loss
AGC_PKC_PKCa_PRKCA_ST	P29350	PTPN6	P17252	PRKCA	S557	R554C	554	Missense	distal	-3	no	18.262	15.522	EPSD	COSMIC	16.704	Loss
AGC_PKC_PKCa_PRKCA_ST	P29350	PTPN6	P17252	PRKCA	S557	R554H	554	Missense	distal	-3	no	18.262	14.405	EPSD	COSMIC;GDSC	16.704	Loss
AGC_PKC_PKCa_PRKCA_ST	P29350	PTPN6	P17252	PRKCA	S582	R581Q	581	Missense	proximal	-1	no	16.827	16.009	EPSD	COSMIC;CCLE	16.704	Loss
AGC_PKC_PKCa_PRKCA_ST	P29350	PTPN6	P17252	PRKCA	S582	K587N	587	Missense	distal	5	no	16.827	16.321	EPSD	COSMIC	16.704	Loss
AGC_PKC_PKCa_PRKCA_ST	P29350	PTPN6	P17252	PRKCA	S591	K587N	587	Missense	distal	-4	no	19.441	18.883	PhosphoSitePlus	COSMIC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	O60674	JAK2	P17252	PRKCA	S936	Y931C	931	Missense	distal	-5	no	16.865	16.698	EPSD	COSMIC	16.704	Loss
AGC_PKC_PKCa_PRKCA_ST	O60674	JAK2	P17252	PRKCA	S936	P933R	933	Missense	distal	-3	no	16.865	20.714	EPSD	COSMIC	16.704	Up-regulation
AGC_PKC_PKCa_PRKCA_ST	O60674	JAK2	P17252	PRKCA	S936	R938Q	938	Missense	proximal	2	no	16.865	13.031	EPSD	COSMIC	16.704	Loss
AGC_PKC_PKCa_PRKCA_ST	O60674	JAK2	P17252	PRKCA	S936	P933Q	933	Missense	distal	-3	no	16.865	17.856	EPSD	COSMIC	16.704	Up-regulation
AGC_PKC_PKCa_PRKCA_ST	O60674	JAK2	P17252	PRKCA	S936	M929L	929	Missense	distal	-7	no	16.865	16.857	EPSD	COSMIC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	P42261	GRIA1	P17252	PRKCA	S306	A303S	303	Missense	distal	-3	no	19.207	20.786	EPSD	COSMIC	16.704	Up-regulation
AGC_PKC_PKCa_PRKCA_ST	P42261	GRIA1	P17252	PRKCA	S306	V299M	299	Missense	distal	-7	no	19.207	19.218	EPSD	COSMIC	16.704	Up-regulation
AGC_PKC_PKCa_PRKCA_ST	P42261	GRIA1	P17252	PRKCA	S453	E457G	457	Missense	distal	4	no	16.799	16.563	EPSD	COSMIC	16.704	Loss
AGC_PKC_PKCa_PRKCA_ST	P42261	GRIA1	P17252	PRKCA	S453	R455C	455	Missense	proximal	2	no	16.799	12.449	EPSD	COSMIC	16.704	Loss
AGC_PKC_PKCa_PRKCA_ST	P42261	GRIA1	P17252	PRKCA	S645	S645F	645	Missense	central	0	yes	17.389	0.000	EPSD	COSMIC	16.704	Loss
AGC_PKC_PKCa_PRKCA_ST	P42261	GRIA1	P17252	PRKCA	S832	E827G	827	Missense	distal	-5	no	16.903	16.920	EPSD	COSMIC	16.704	Up-regulation
AGC_PKC_PKCa_PRKCA_ST	P42261	GRIA1	P17252	PRKCA	S832	Y830H	830	Missense	proximal	-2	no	16.903	15.078	EPSD	COSMIC	16.704	Loss
AGC_PKC_PKCa_PRKCA_ST	P42261	GRIA1	P17252	PRKCA	S832	E827K	827	Missense	distal	-5	no	16.903	17.198	EPSD	COSMIC	16.704	Up-regulation
AGC_PKC_PKCa_PRKCA_ST	P42261	GRIA1	P17252	PRKCA	S832	E835K	835	Missense	distal	3	no	16.903	17.519	EPSD	COSMIC	16.704	Up-regulation
AGC_PKC_PKCa_PRKCA_ST	P42261	GRIA1	P17252	PRKCA	S832	K831N	831	Missense	proximal	-1	no	16.903	16.302	EPSD	COSMIC	16.704	Loss
AGC_PKC_PKCa_PRKCA_ST	P42261	GRIA1	P17252	PRKCA	S834	E835K	835	Missense	proximal	1	no	16.265	17.869	EPSD;PhosphoSitePlus	COSMIC	16.704	Gain
AGC_PKC_PKCa_PRKCA_ST	P42261	GRIA1	P17252	PRKCA	S836	Y830H	830	Missense	distal	-6	no	25.598	25.657	PhosphoSitePlus;EPSD	COSMIC	16.704	Up-regulation
AGC_PKC_PKCa_PRKCA_ST	P42261	GRIA1	P17252	PRKCA	S836	E835K	835	Missense	proximal	-1	no	25.598	26.024	PhosphoSitePlus;EPSD	COSMIC	16.704	Up-regulation
AGC_PKC_PKCa_PRKCA_ST	P42261	GRIA1	P17252	PRKCA	S836	G841S	841	Missense	distal	5	no	25.598	25.737	PhosphoSitePlus;EPSD	COSMIC	16.704	Up-regulation
AGC_PKC_PKCa_PRKCA_ST	P42261	GRIA1	P17252	PRKCA	S836	K831N	831	Missense	distal	-5	no	25.598	25.255	PhosphoSitePlus;EPSD	COSMIC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	P42261	GRIA1	P17252	PRKCA	S849	P846Q	846	Missense	distal	-3	no	16.504	17.495	EPSD;PhosphoSitePlus	COSMIC;GDSC	16.704	Gain
AGC_PKC_PKCa_PRKCA_ST	P42261	GRIA1	P17252	PRKCA	T858	R855Q	855	Missense	distal	-3	no	17.098	14.240	EPSD	COSMIC	16.704	Loss
AGC_PKC_PKCa_PRKCA_ST	P42261	GRIA1	P17252	PRKCA	T858	S863N	863	Missense	distal	5	no	17.098	16.877	EPSD	COSMIC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	P42261	GRIA1	P17252	PRKCA	T858	L859F	859	Missense	proximal	1	no	17.098	17.756	EPSD	COSMIC	16.704	Up-regulation
AGC_PKC_PKCa_PRKCA_ST	P42261	GRIA1	P17252	PRKCA	T858	R861P	861	Missense	distal	3	no	17.098	15.567	EPSD	COSMIC	16.704	Loss
AGC_PKC_PKCa_PRKCA_ST	Q14994	NR1I3	P17252	PRKCA	T38	P45L	45	Missense	distal	7	no	18.555	18.521	PhosphoSitePlus	COSMIC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	Q14994	NR1I3	P17252	PRKCA	T38	I43T	43	Missense	distal	5	no	18.555	18.573	PhosphoSitePlus	COSMIC	16.704	Up-regulation
AGC_PKC_PKCa_PRKCA_ST	Q14994	NR1I3	P17252	PRKCA	T38	G33D	33	Missense	distal	-5	no	18.555	18.460	PhosphoSitePlus	COSMIC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	P35869	AHR	P17252	PRKCA	S68	D65G	65	Missense	distal	-3	no	15.312	17.092	EPSD	COSMIC	16.704	Gain
AGC_PKC_PKCa_PRKCA_ST	P35869	AHR	P17252	PRKCA	T92	P91S	91	Missense	proximal	-1	no	16.571	16.871	EPSD	COSMIC	16.704	Gain
AGC_PKC_PKCa_PRKCA_ST	P35869	AHR	P17252	PRKCA	T92	G96A	96	Missense	distal	4	no	16.571	16.945	EPSD	COSMIC	16.704	Gain
AGC_PKC_PKCa_PRKCA_ST	P35611	ADD1	P17252	PRKCA	S358	G361V	361	Missense	distal	3	no	17.039	15.825	EPSD	COSMIC	16.704	Loss
AGC_PKC_PKCa_PRKCA_ST	P35611	ADD1	P17252	PRKCA	S436	T429A	429	Missense	distal	-7	no	18.846	18.851	EPSD	COSMIC	16.704	Up-regulation
AGC_PKC_PKCa_PRKCA_ST	P35611	ADD1	P17252	PRKCA	S669	P670F	670	Missense	proximal	1	no	17.233	18.317	EPSD	COSMIC	16.704	Up-regulation
AGC_PKC_PKCa_PRKCA_ST	P35611	ADD1	P17252	PRKCA	S716	G709V	709	Missense	distal	-7	no	19.667	19.663	EPSD;PhosphoSitePlus	COSMIC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	P35611	ADD1	P17252	PRKCA	S716	S710F	710	Missense	distal	-6	no	19.667	19.582	EPSD;PhosphoSitePlus	COSMIC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	P35611	ADD1	P17252	PRKCA	S716	G712D	712	Missense	distal	-4	no	19.667	18.897	EPSD;PhosphoSitePlus	COSMIC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	P35611	ADD1	P17252	PRKCA	S726	S726L	726	Missense	central	0	yes	18.633	0.000	PhosphoSitePlus;EPSD	COSMIC	16.704	Loss
AGC_PKC_PKCa_PRKCA_ST	P35611	ADD1	P17252	PRKCA	S731	S726L	726	Missense	distal	-5	no	18.603	18.902	EPSD	COSMIC	16.704	Up-regulation
AGC_PKC_PKCa_PRKCA_ST	P49802	RGS7	P17252	PRKCA	S217	I214V	214	Missense	distal	-3	no	16.336	17.134	EPSD	COSMIC	16.704	Gain
AGC_PKC_PKCa_PRKCA_ST	P49802	RGS7	P17252	PRKCA	S218	I214V	214	Missense	distal	-4	no	18.906	18.876	EPSD	COSMIC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	P49802	RGS7	P17252	PRKCA	S218	D213N	213	Missense	distal	-5	no	18.906	18.935	EPSD	COSMIC	16.704	Up-regulation
AGC_PKC_PKCa_PRKCA_ST	P49802	RGS7	P17252	PRKCA	S229	S229R	229	Missense	central	0	yes	17.673	0.000	EPSD	COSMIC	16.704	Loss
AGC_PKC_PKCa_PRKCA_ST	P49802	RGS7	P17252	PRKCA	S229	S229N	229	Missense	central	0	yes	17.673	0.000	EPSD	COSMIC	16.704	Loss
AGC_PKC_PKCa_PRKCA_ST	P49802	RGS7	P17252	PRKCA	S229	L233S	233	Missense	distal	4	no	17.673	18.465	EPSD	COSMIC	16.704	Up-regulation
AGC_PKC_PKCa_PRKCA_ST	P49802	RGS7	P17252	PRKCA	S229	G232N	232	Missense	distal	3	no	17.673	16.743	EPSD	COSMIC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	P49802	RGS7	P17252	PRKCA	S229	N235S	235	Missense	distal	6	no	17.673	17.775	EPSD	COSMIC	16.704	Up-regulation
AGC_PKC_PKCa_PRKCA_ST	P49802	RGS7	P17252	PRKCA	S323	Q325K	325	Missense	proximal	2	no	17.009	20.422	EPSD	COSMIC	16.704	Up-regulation
AGC_PKC_PKCa_PRKCA_ST	P49802	RGS7	P17252	PRKCA	S323	R329Q	329	Missense	distal	6	no	17.009	16.886	EPSD	COSMIC;GDSC;CCLE	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	P49802	RGS7	P17252	PRKCA	S323	K320N	320	Missense	distal	-3	no	17.009	14.809	EPSD	COSMIC	16.704	Loss
AGC_PKC_PKCa_PRKCA_ST	P49802	RGS7	P17252	PRKCA	S323	E321K	321	Missense	proximal	-2	no	17.009	19.508	EPSD	COSMIC	16.704	Up-regulation
AGC_PKC_PKCa_PRKCA_ST	P49802	RGS7	P17252	PRKCA	S323	P322S	322	Missense	proximal	-1	no	17.009	17.309	EPSD	COSMIC	16.704	Up-regulation
AGC_PKC_PKCa_PRKCA_ST	P49802	RGS7	P17252	PRKCA	S323	V327I	327	Missense	distal	4	no	17.009	16.886	EPSD	COSMIC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	P49802	RGS7	P17252	PRKCA	S434	S432T	432	Missense	proximal	-2	no	16.377	16.785	PhosphoSitePlus	COSMIC	16.704	Gain
AGC_PKC_PKCa_PRKCA_ST	P49802	RGS7	P17252	PRKCA	S463	R461M	461	Missense	proximal	-2	no	20.138	18.156	EPSD	COSMIC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	P49802	RGS7	P17252	PRKCA	S463	F467L	467	Missense	distal	4	no	20.138	19.707	EPSD	COSMIC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	Q92681	RSC1A1	P17252	PRKCA	S66	N65S	65	Missense	proximal	-1	no	17.835	17.993	EPSD	COSMIC	16.704	Up-regulation
AGC_PKC_PKCa_PRKCA_ST	Q92681	RSC1A1	P17252	PRKCA	S66	E61K	61	Missense	distal	-5	no	17.835	18.129	EPSD	COSMIC	16.704	Up-regulation
AGC_PKC_PKCa_PRKCA_ST	P81274	GPSM2	P17252	PRKCA	S408	R406Q	406	Missense	proximal	-2	no	21.986	20.227	PhosphoSitePlus	COSMIC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	P81274	GPSM2	P17252	PRKCA	S441	A438V	438	Missense	distal	-3	no	18.994	19.753	EPSD	COSMIC	16.704	Up-regulation
AGC_PKC_PKCa_PRKCA_ST	P81274	GPSM2	P17252	PRKCA	S478	N477K	477	Missense	proximal	-1	no	17.087	17.689	EPSD	COSMIC	16.704	Up-regulation
AGC_PKC_PKCa_PRKCA_ST	P81274	GPSM2	P17252	PRKCA	S478	P476S	476	Missense	proximal	-2	no	17.087	16.827	EPSD	COSMIC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	P81274	GPSM2	P17252	PRKCA	S556	R557L	557	Missense	proximal	1	no	18.532	18.185	EPSD	COSMIC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	P81274	GPSM2	P17252	PRKCA	S556	R563S	563	Missense	distal	7	no	18.532	18.486	EPSD	COSMIC;GDSC;CCLE	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	P81274	GPSM2	P17252	PRKCA	S565	R563S	563	Missense	proximal	-2	no	18.244	14.942	EPSD	COSMIC;GDSC;CCLE	16.704	Loss
AGC_PKC_PKCa_PRKCA_ST	P81274	GPSM2	P17252	PRKCA	S677	G678W	678	Missense	proximal	1	no	18.308	18.537	EPSD	COSMIC	16.704	Up-regulation
AGC_PKC_PKCa_PRKCA_ST	P11309	PIM1	P17252	PRKCA	S28	L34Q	34	Missense	distal	6	no	25.045	25.004	EPSD	COSMIC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	P11309	PIM1	P17252	PRKCA	S65	H68N	68	Missense	distal	3	no	22.985	22.127	PhosphoSitePlus	COSMIC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	P11309	PIM1	P17252	PRKCA	S65	S59F	59	Missense	distal	-6	no	22.985	22.900	PhosphoSitePlus	COSMIC;GDSC;CCLE	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	P11309	PIM1	P17252	PRKCA	S65	H68D	68	Missense	distal	3	no	22.985	21.972	PhosphoSitePlus	COSMIC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	P11309	PIM1	P17252	PRKCA	S65	S59C	59	Missense	distal	-6	no	22.985	22.689	PhosphoSitePlus	COSMIC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	Q9NS23	RASSF1	P17252	PRKCA	S182	P181S	181	Missense	proximal	-1	no	19.774	20.074	EPSD	COSMIC;GDSC;CCLE	16.704	Up-regulation
AGC_PKC_PKCa_PRKCA_ST	Q9NS23	RASSF1	P17252	PRKCA	S182	P177S	177	Missense	distal	-5	no	19.774	19.448	EPSD	COSMIC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	Q9NS23	RASSF1	P17252	PRKCA	S182	S179R	179	Missense	distal	-3	no	19.774	22.644	EPSD	COSMIC	16.704	Up-regulation
AGC_PKC_PKCa_PRKCA_ST	Q9NS23	RASSF1	P17252	PRKCA	S182	L189Q	189	Missense	distal	7	no	19.774	19.813	EPSD	COSMIC	16.704	Up-regulation
AGC_PKC_PKCa_PRKCA_ST	Q9NS23	RASSF1	P17252	PRKCA	S182	R176C	176	Missense	distal	-6	no	19.774	19.404	EPSD	COSMIC;GDSC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	Q9NS23	RASSF1	P17252	PRKCA	S182	S183R	183	Missense	proximal	1	no	19.774	20.947	EPSD	COSMIC	16.704	Up-regulation
AGC_PKC_PKCa_PRKCA_ST	Q9NS23	RASSF1	P17252	PRKCA	S182	R176H	176	Missense	distal	-6	no	19.774	19.706	EPSD	COSMIC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	Q9NS23	RASSF1	P17252	PRKCA	S183	P181S	181	Missense	proximal	-2	no	18.397	18.138	EPSD	COSMIC;GDSC;CCLE	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	Q9NS23	RASSF1	P17252	PRKCA	S183	P177S	177	Missense	distal	-6	no	18.397	18.429	EPSD	COSMIC	16.704	Up-regulation
AGC_PKC_PKCa_PRKCA_ST	Q9NS23	RASSF1	P17252	PRKCA	S183	S179R	179	Missense	distal	-4	no	18.397	18.590	EPSD	COSMIC	16.704	Up-regulation
AGC_PKC_PKCa_PRKCA_ST	Q9NS23	RASSF1	P17252	PRKCA	S183	L189Q	189	Missense	distal	6	no	18.397	18.357	EPSD	COSMIC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	Q9NS23	RASSF1	P17252	PRKCA	S183	R176C	176	Missense	distal	-7	no	18.397	18.378	EPSD	COSMIC;GDSC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	Q9NS23	RASSF1	P17252	PRKCA	S183	S183R	183	Missense	central	0	yes	18.397	0.000	EPSD	COSMIC	16.704	Loss
AGC_PKC_PKCa_PRKCA_ST	Q9NS23	RASSF1	P17252	PRKCA	S183	R176H	176	Missense	distal	-7	no	18.397	18.390	EPSD	COSMIC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	Q9NS23	RASSF1	P17252	PRKCA	S188	P181S	181	Missense	distal	-7	no	17.758	17.761	EPSD	COSMIC;GDSC;CCLE	16.704	Up-regulation
AGC_PKC_PKCa_PRKCA_ST	Q9NS23	RASSF1	P17252	PRKCA	S188	R193W	193	Missense	distal	5	no	17.758	17.250	EPSD	COSMIC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	Q9NS23	RASSF1	P17252	PRKCA	S188	A192V	192	Missense	distal	4	no	17.758	16.420	EPSD	COSMIC	16.704	Loss
AGC_PKC_PKCa_PRKCA_ST	Q9NS23	RASSF1	P17252	PRKCA	S188	L189Q	189	Missense	proximal	1	no	17.758	17.988	EPSD	COSMIC	16.704	Up-regulation
AGC_PKC_PKCa_PRKCA_ST	Q9NS23	RASSF1	P17252	PRKCA	S188	S183R	183	Missense	distal	-5	no	17.758	18.184	EPSD	COSMIC	16.704	Up-regulation
AGC_PKC_PKCa_PRKCA_ST	Q9NS23	RASSF1	P17252	PRKCA	S188	R194Q	194	Missense	distal	6	no	17.758	17.635	EPSD	COSMIC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	Q9NS23	RASSF1	P17252	PRKCA	S201	R205H	205	Missense	distal	4	no	24.182	23.899	EPSD	COSMIC;CCLE	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	Q9NS23	RASSF1	P17252	PRKCA	S201	T200I	200	Missense	proximal	-1	no	24.182	23.277	EPSD	COSMIC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	Q9NS23	RASSF1	P17252	PRKCA	S201	G197R	197	Missense	distal	-4	no	24.182	24.283	EPSD	COSMIC	16.704	Up-regulation
AGC_PKC_PKCa_PRKCA_ST	Q9NS23	RASSF1	P17252	PRKCA	S201	R194Q	194	Missense	distal	-7	no	24.182	24.173	EPSD	COSMIC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	Q9NS23	RASSF1	P17252	PRKCA	T206	R205H	205	Missense	proximal	-1	no	17.444	17.121	EPSD	COSMIC;CCLE	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	Q9NS23	RASSF1	P17252	PRKCA	T206	T200I	200	Missense	distal	-6	no	17.444	17.473	EPSD	COSMIC	16.704	Up-regulation
AGC_PKC_PKCa_PRKCA_ST	Q9NS23	RASSF1	P17252	PRKCA	S207	R205H	205	Missense	proximal	-2	no	21.710	17.156	EPSD	COSMIC;CCLE	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	Q9NS23	RASSF1	P17252	PRKCA	S207	T200I	200	Missense	distal	-7	no	21.710	21.703	EPSD	COSMIC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	P35503	UGT1A3	P17252	PRKCA	S28	Q23H	23	Missense	distal	-5	no	19.483	19.279	EPSD	COSMIC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	P35503	UGT1A3	P17252	PRKCA	S43	S39I	39	Missense	distal	-4	no	18.448	18.006	PhosphoSitePlus	COSMIC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	P35503	UGT1A3	P17252	PRKCA	S43	S39R	39	Missense	distal	-4	no	18.448	18.641	PhosphoSitePlus	COSMIC	16.704	Up-regulation
AGC_PKC_PKCa_PRKCA_ST	P35503	UGT1A3	P17252	PRKCA	S43	R45Q	45	Missense	proximal	2	no	18.448	14.614	PhosphoSitePlus	COSMIC	16.704	Loss
AGC_PKC_PKCa_PRKCA_ST	P35503	UGT1A3	P17252	PRKCA	S43	R49W	49	Missense	distal	6	no	18.448	18.200	PhosphoSitePlus	COSMIC;GDSC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	P35503	UGT1A3	P17252	PRKCA	S43	G38D	38	Missense	distal	-5	no	18.448	18.353	PhosphoSitePlus	COSMIC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	Q99801	NKX3-1	P17252	PRKCA	S48	Q49H	49	Missense	proximal	1	no	22.062	21.365	PhosphoSitePlus	COSMIC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	Q99801	NKX3-1	P17252	PRKCA	S48	R45S	45	Missense	distal	-3	no	22.062	19.192	PhosphoSitePlus	COSMIC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	Q99801	NKX3-1	P17252	PRKCA	S48	R52S	52	Missense	distal	4	no	22.062	21.815	PhosphoSitePlus	COSMIC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	Q99801	NKX3-1	P17252	PRKCA	S185	E187K	187	Missense	proximal	2	no	13.827	19.106	EPSD	COSMIC	16.704	Gain
AGC_PKC_PKCa_PRKCA_ST	Q13224	GRIN2B	P17252	PRKCA	S383	S383F	383	Missense	central	0	yes	17.582	0.000	EPSD	COSMIC	16.704	Loss
AGC_PKC_PKCa_PRKCA_ST	Q13224	GRIN2B	P17252	PRKCA	S882	E879K	879	Missense	distal	-3	no	15.776	18.688	EPSD	COSMIC	16.704	Gain
AGC_PKC_PKCa_PRKCA_ST	Q13224	GRIN2B	P17252	PRKCA	S1043	G1040D	1040	Missense	distal	-3	no	19.592	17.812	EPSD	COSMIC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	Q13224	GRIN2B	P17252	PRKCA	S1043	F1042L	1042	Missense	proximal	-1	no	19.592	19.880	EPSD	COSMIC	16.704	Up-regulation
AGC_PKC_PKCa_PRKCA_ST	Q13224	GRIN2B	P17252	PRKCA	S1043	R1048H	1048	Missense	distal	5	no	19.592	19.333	EPSD	COSMIC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	Q13224	GRIN2B	P17252	PRKCA	S1043	K1041E	1041	Missense	proximal	-2	no	19.592	17.093	EPSD	COSMIC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	Q13224	GRIN2B	P17252	PRKCA	S1166	R1164H	1164	Missense	proximal	-2	no	19.183	14.629	EPSD	COSMIC	16.704	Loss
AGC_PKC_PKCa_PRKCA_ST	Q13224	GRIN2B	P17252	PRKCA	S1166	D1165N	1165	Missense	proximal	-1	no	19.183	19.520	EPSD	COSMIC	16.704	Up-regulation
AGC_PKC_PKCa_PRKCA_ST	Q13224	GRIN2B	P17252	PRKCA	S1166	V1167I	1167	Missense	proximal	1	no	19.183	19.894	EPSD	COSMIC	16.704	Up-regulation
AGC_PKC_PKCa_PRKCA_ST	Q13224	GRIN2B	P17252	PRKCA	S1166	R1164S	1164	Missense	proximal	-2	no	19.183	15.881	EPSD	COSMIC	16.704	Loss
AGC_PKC_PKCa_PRKCA_ST	Q13224	GRIN2B	P17252	PRKCA	S1303	S1303F	1303	Missense	central	0	yes	18.841	0.000	EPSD	COSMIC	16.704	Loss
AGC_PKC_PKCa_PRKCA_ST	Q13224	GRIN2B	P17252	PRKCA	S1303	D1309N	1309	Missense	distal	6	no	18.841	18.757	EPSD	COSMIC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	Q13224	GRIN2B	P17252	PRKCA	S1303	R1299L	1299	Missense	distal	-4	no	18.841	18.217	EPSD	COSMIC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	Q13224	GRIN2B	P17252	PRKCA	S1323	L1317M	1317	Missense	distal	-6	no	21.123	21.186	PhosphoSitePlus	COSMIC	16.704	Up-regulation
AGC_PKC_PKCa_PRKCA_ST	Q13224	GRIN2B	P17252	PRKCA	S1323	P1319T	1319	Missense	distal	-4	no	21.123	20.633	PhosphoSitePlus	COSMIC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	Q13224	GRIN2B	P17252	PRKCA	S1323	K1327N	1327	Missense	distal	4	no	21.123	19.996	PhosphoSitePlus	COSMIC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	Q13224	GRIN2B	P17252	PRKCA	S1323	V1322I	1322	Missense	proximal	-1	no	21.123	21.303	PhosphoSitePlus	COSMIC	16.704	Up-regulation
AGC_PKC_PKCa_PRKCA_ST	Q13224	GRIN2B	P17252	PRKCA	S1323	R1320C	1320	Missense	distal	-3	no	21.123	18.384	PhosphoSitePlus	COSMIC;CCLE	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	Q13224	GRIN2B	P17252	PRKCA	T1410	V1411E	1411	Missense	proximal	1	no	18.718	17.374	EPSD	COSMIC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	Q13224	GRIN2B	P17252	PRKCA	T1410	A1414V	1414	Missense	distal	4	no	18.718	17.380	EPSD	COSMIC;CCLE	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	Q96MS0	ROBO3	P17252	PRKCA	T215	E209G	209	Missense	distal	-6	no	20.043	20.010	EPSD	COSMIC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	Q96MS0	ROBO3	P17252	PRKCA	T215	R217C	217	Missense	proximal	2	no	20.043	15.692	EPSD	COSMIC	16.704	Loss
AGC_PKC_PKCa_PRKCA_ST	Q96MS0	ROBO3	P17252	PRKCA	T215	K220R	220	Missense	distal	5	no	20.043	19.899	EPSD	COSMIC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	Q96MS0	ROBO3	P17252	PRKCA	S404	S402L	402	Missense	proximal	-2	no	19.215	19.829	EPSD	COSMIC	16.704	Up-regulation
AGC_PKC_PKCa_PRKCA_ST	Q96MS0	ROBO3	P17252	PRKCA	S725	L721P	721	Missense	distal	-4	no	17.882	18.141	EPSD	COSMIC	16.704	Up-regulation
AGC_PKC_PKCa_PRKCA_ST	Q96MS0	ROBO3	P17252	PRKCA	T729	P735S	735	Missense	distal	6	no	16.765	16.732	EPSD	COSMIC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	Q96MS0	ROBO3	P17252	PRKCA	S1189	Q1192H	1192	Missense	distal	3	no	15.126	16.867	EPSD	COSMIC	16.704	Gain
AGC_PKC_PKCa_PRKCA_ST	Q96MS0	ROBO3	P17252	PRKCA	S1293	R1298C	1298	Missense	distal	5	no	16.763	16.032	EPSD	COSMIC;CCLE	16.704	Loss
AGC_PKC_PKCa_PRKCA_ST	Q96MS0	ROBO3	P17252	PRKCA	S1293	G1300A	1300	Missense	distal	7	no	16.763	16.740	EPSD	COSMIC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	Q96MS0	ROBO3	P17252	PRKCA	S1330	R1334W	1334	Missense	distal	4	no	17.744	16.208	PhosphoSitePlus	COSMIC	16.704	Loss
AGC_PKC_PKCa_PRKCA_ST	Q96MS0	ROBO3	P17252	PRKCA	S1330	Y1326C	1326	Missense	distal	-4	no	17.744	16.787	PhosphoSitePlus	COSMIC;GDSC;CCLE	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	Q96MS0	ROBO3	P17252	PRKCA	S1358	R1365Q	1365	Missense	distal	7	no	17.869	17.865	EPSD	COSMIC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	Q96MS0	ROBO3	P17252	PRKCA	S1358	R1363W	1363	Missense	distal	5	no	17.869	17.361	EPSD	COSMIC;CCLE	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	P06127	CD5	P17252	PRKCA	S42	R36K	36	Missense	distal	-6	no	17.565	17.558	EPSD	COSMIC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	P06127	CD5	P17252	PRKCA	S42	G46S	46	Missense	distal	4	no	17.565	17.922	EPSD	COSMIC	16.704	Up-regulation
AGC_PKC_PKCa_PRKCA_ST	P06127	CD5	P17252	PRKCA	T142	T142M	142	Missense	central	0	yes	17.394	0.000	EPSD	COSMIC	16.704	Loss
AGC_PKC_PKCa_PRKCA_ST	P06127	CD5	P17252	PRKCA	T142	P146L	146	Missense	distal	4	no	17.394	16.802	EPSD	COSMIC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	P06127	CD5	P17252	PRKCA	S309	S309L	309	Missense	central	0	yes	19.187	0.000	EPSD	COSMIC	16.704	Loss
AGC_PKC_PKCa_PRKCA_ST	P06127	CD5	P17252	PRKCA	T436	R431H	431	Missense	distal	-5	no	16.941	16.586	EPSD;PhosphoSitePlus	COSMIC	16.704	Loss
AGC_PKC_PKCa_PRKCA_ST	P06127	CD5	P17252	PRKCA	T436	T434M	434	Missense	proximal	-2	no	16.941	17.854	EPSD;PhosphoSitePlus	COSMIC	16.704	Up-regulation
AGC_PKC_PKCa_PRKCA_ST	P06239	LCK	P17252	PRKCA	S133	P126S	126	Missense	distal	-7	no	18.873	18.876	EPSD	COSMIC	16.704	Up-regulation
AGC_PKC_PKCa_PRKCA_ST	P06239	LCK	P17252	PRKCA	S133	E138G	138	Missense	distal	5	no	18.873	18.862	EPSD	COSMIC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	P06239	LCK	P17252	PRKCA	T159	G161R	161	Missense	proximal	2	no	11.613	16.858	EPSD	COSMIC	16.704	Gain
AGC_PKC_PKCa_PRKCA_ST	P06239	LCK	P17252	PRKCA	S166	G161R	161	Missense	distal	-5	no	18.998	19.289	EPSD	COSMIC	16.704	Up-regulation
AGC_PKC_PKCa_PRKCA_ST	P06239	LCK	P17252	PRKCA	S166	A160V	160	Missense	distal	-6	no	18.998	18.922	EPSD	COSMIC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	P06239	LCK	P17252	PRKCA	S194	I197F	197	Missense	distal	3	no	16.305	16.951	EPSD	COSMIC	16.704	Gain
AGC_PKC_PKCa_PRKCA_ST	P06239	LCK	P17252	PRKCA	S274	V270M	270	Missense	distal	-4	no	17.165	17.909	EPSD	COSMIC	16.704	Up-regulation
AGC_PKC_PKCa_PRKCA_ST	P06239	LCK	P17252	PRKCA	S274	T268M	268	Missense	distal	-6	no	17.165	17.288	EPSD	COSMIC	16.704	Up-regulation
AGC_PKC_PKCa_PRKCA_ST	P06239	LCK	P17252	PRKCA	S274	K269E	269	Missense	distal	-5	no	17.165	16.871	EPSD	COSMIC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	P06239	LCK	P17252	PRKCA	S274	K276E	276	Missense	proximal	2	no	17.165	11.886	EPSD	COSMIC	16.704	Loss
AGC_PKC_PKCa_PRKCA_ST	P32004	L1CAM	P17252	PRKCA	T527	T527A	527	Missense	central	0	yes	16.781	0.000	EPSD	COSMIC	16.704	Loss
AGC_PKC_PKCa_PRKCA_ST	P32004	L1CAM	P17252	PRKCA	T527	Q522R	522	Missense	distal	-5	no	16.781	16.933	EPSD	COSMIC	16.704	Up-regulation
AGC_PKC_PKCa_PRKCA_ST	P32004	L1CAM	P17252	PRKCA	T527	T527I	527	Missense	central	0	yes	16.781	0.000	EPSD	COSMIC	16.704	Loss
AGC_PKC_PKCa_PRKCA_ST	P32004	L1CAM	P17252	PRKCA	S1146	R1145H	1145	Missense	proximal	-1	no	17.681	17.358	EPSD	COSMIC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	P32004	L1CAM	P17252	PRKCA	S1146	G1148D	1148	Missense	proximal	2	no	17.681	17.648	EPSD	COSMIC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	P32004	L1CAM	P17252	PRKCA	S1152	R1145H	1145	Missense	distal	-7	no	20.622	20.615	EPSD	COSMIC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	P32004	L1CAM	P17252	PRKCA	S1152	G1148D	1148	Missense	distal	-4	no	20.622	19.852	EPSD	COSMIC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	P32004	L1CAM	P17252	PRKCA	S1194	I1199M	1199	Missense	distal	5	no	16.835	17.156	EPSD	COSMIC	16.704	Up-regulation
AGC_PKC_PKCa_PRKCA_ST	P32004	L1CAM	P17252	PRKCA	S1194	S1190T	1190	Missense	distal	-4	no	16.835	16.174	EPSD	COSMIC	16.704	Loss
AGC_PKC_PKCa_PRKCA_ST	P32004	L1CAM	P17252	PRKCA	S1230	A1237V	1237	Missense	distal	7	no	19.747	19.692	EPSD	COSMIC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	P32004	L1CAM	P17252	PRKCA	S1230	G1223C	1223	Missense	distal	-7	no	19.747	19.737	EPSD	COSMIC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	P32004	L1CAM	P17252	PRKCA	S1230	G1223V	1223	Missense	distal	-7	no	19.747	19.742	EPSD	COSMIC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	P32004	L1CAM	P17252	PRKCA	S1230	G1223S	1223	Missense	distal	-7	no	19.747	19.751	EPSD	COSMIC	16.704	Up-regulation
AGC_PKC_PKCa_PRKCA_ST	P32004	L1CAM	P17252	PRKCA	S1230	G1231S	1231	Missense	proximal	1	no	19.747	19.526	EPSD	COSMIC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	P32004	L1CAM	P17252	PRKCA	S1230	G1227S	1227	Missense	distal	-3	no	19.747	20.139	EPSD	COSMIC	16.704	Up-regulation
AGC_PKC_PKCa_PRKCA_ST	P32004	L1CAM	P17252	PRKCA	S1230	G1231C	1231	Missense	proximal	1	no	19.747	17.864	EPSD	COSMIC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	Q01959	SLC6A3	P17252	PRKCA	S2	S7A	7	Missense	distal	5	no	18.203	18.306	EPSD	COSMIC	16.704	Up-regulation
AGC_PKC_PKCa_PRKCA_ST	Q01959	SLC6A3	P17252	PRKCA	T62	G64R	64	Missense	proximal	2	no	13.284	18.529	EPSD	COSMIC	16.704	Gain
AGC_PKC_PKCa_PRKCA_ST	Q01959	SLC6A3	P17252	PRKCA	S262	G263E	263	Missense	proximal	1	no	17.762	17.149	EPSD	COSMIC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	Q01959	SLC6A3	P17252	PRKCA	T613	E608K	608	Missense	distal	-5	no	16.555	16.849	EPSD	COSMIC	16.704	Gain
AGC_PKC_PKCa_PRKCA_ST	O15350	TP73	P17252	PRKCA	S289	G292C	292	Missense	distal	3	no	19.811	17.833	EPSD	COSMIC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	O15350	TP73	P17252	PRKCA	S326	S333R	333	Missense	distal	7	no	19.187	19.233	EPSD	COSMIC	16.704	Up-regulation
AGC_PKC_PKCa_PRKCA_ST	O15350	TP73	P17252	PRKCA	S471	S468N	468	Missense	distal	-3	no	17.254	15.897	EPSD	COSMIC	16.704	Loss
AGC_PKC_PKCa_PRKCA_ST	O15350	TP73	P17252	PRKCA	S471	S474P	474	Missense	distal	3	no	17.254	17.114	EPSD	COSMIC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	O15350	TP73	P17252	PRKCA	S471	G478R	478	Missense	distal	7	no	17.254	17.278	EPSD	COSMIC;CCLE	16.704	Up-regulation
AGC_PKC_PKCa_PRKCA_ST	O15350	TP73	P17252	PRKCA	S471	G464S	464	Missense	distal	-7	no	17.254	17.258	EPSD	COSMIC	16.704	Up-regulation
AGC_PKC_PKCa_PRKCA_ST	P28329	CHAT	P17252	PRKCA	S244	L248V	248	Missense	distal	4	no	17.598	17.068	EPSD	COSMIC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	P28329	CHAT	P17252	PRKCA	S244	L248P	248	Missense	distal	4	no	17.598	18.190	EPSD	COSMIC	16.704	Up-regulation
AGC_PKC_PKCa_PRKCA_ST	P28329	CHAT	P17252	PRKCA	S244	S240F	240	Missense	distal	-4	no	17.598	17.539	EPSD	COSMIC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	P28329	CHAT	P17252	PRKCA	S244	L243F	243	Missense	proximal	-1	no	17.598	17.309	EPSD	COSMIC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	P28329	CHAT	P17252	PRKCA	S244	D250N	250	Missense	distal	6	no	17.598	17.513	EPSD	COSMIC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	P28329	CHAT	P17252	PRKCA	S244	S237N	237	Missense	distal	-7	no	17.598	17.593	EPSD	COSMIC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	P28329	CHAT	P17252	PRKCA	T373	K370R	370	Missense	distal	-3	no	16.663	18.689	EPSD	COSMIC	16.704	Gain
AGC_PKC_PKCa_PRKCA_ST	P28329	CHAT	P17252	PRKCA	T373	V369M	369	Missense	distal	-4	no	16.663	17.407	EPSD	COSMIC	16.704	Gain
AGC_PKC_PKCa_PRKCA_ST	P28329	CHAT	P17252	PRKCA	T373	D376G	376	Missense	distal	3	no	16.663	17.748	EPSD	COSMIC	16.704	Gain
AGC_PKC_PKCa_PRKCA_ST	P28329	CHAT	P17252	PRKCA	S464	R466Q	466	Missense	proximal	2	no	18.756	14.922	EPSD	COSMIC	16.704	Loss
AGC_PKC_PKCa_PRKCA_ST	P28329	CHAT	P17252	PRKCA	S464	R466L	466	Missense	proximal	2	no	18.756	13.769	EPSD	COSMIC	16.704	Loss
AGC_PKC_PKCa_PRKCA_ST	P28329	CHAT	P17252	PRKCA	S465	R466Q	466	Missense	proximal	1	no	18.460	18.343	EPSD	COSMIC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	P28329	CHAT	P17252	PRKCA	S465	R466L	466	Missense	proximal	1	no	18.460	18.113	EPSD	COSMIC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	P28329	CHAT	P17252	PRKCA	S473	A479T	479	Missense	distal	6	no	18.312	18.234	EPSD	COSMIC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	P28329	CHAT	P17252	PRKCA	S473	R466Q	466	Missense	distal	-7	no	18.312	18.303	EPSD	COSMIC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	P28329	CHAT	P17252	PRKCA	S473	R466L	466	Missense	distal	-7	no	18.312	18.301	EPSD	COSMIC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	P28329	CHAT	P17252	PRKCA	S473	P478S	478	Missense	distal	5	no	18.312	18.152	EPSD	COSMIC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	P28329	CHAT	P17252	PRKCA	S473	S475G	475	Missense	proximal	2	no	18.312	17.686	EPSD	COSMIC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	P28329	CHAT	P17252	PRKCA	T553	E555K	555	Missense	proximal	2	no	11.849	17.128	EPSD	COSMIC	16.704	Gain
AGC_PKC_PKCa_PRKCA_ST	P28329	CHAT	P17252	PRKCA	S558	E555K	555	Missense	distal	-3	no	19.146	22.058	EPSD	COSMIC	16.704	Up-regulation
AGC_PKC_PKCa_PRKCA_ST	P28329	CHAT	P17252	PRKCA	S558	A557T	557	Missense	proximal	-1	no	19.146	19.326	EPSD	COSMIC;GDSC	16.704	Up-regulation
AGC_PKC_PKCa_PRKCA_ST	P28329	CHAT	P17252	PRKCA	S558	R560C	560	Missense	proximal	2	no	19.146	14.795	EPSD	COSMIC	16.704	Loss
AGC_PKC_PKCa_PRKCA_ST	P28329	CHAT	P17252	PRKCA	S558	V551A	551	Missense	distal	-7	no	19.146	19.156	EPSD	COSMIC	16.704	Up-regulation
AGC_PKC_PKCa_PRKCA_ST	P28329	CHAT	P17252	PRKCA	S594	E595K	595	Missense	proximal	1	no	15.859	17.463	EPSD	COSMIC	16.704	Gain
AGC_PKC_PKCa_PRKCA_ST	P06401	PGR	P17252	PRKCA	S20	E22K	22	Missense	proximal	2	no	13.481	18.760	EPSD	COSMIC	16.704	Gain
AGC_PKC_PKCa_PRKCA_ST	P06401	PGR	P17252	PRKCA	S162	S168F	168	Missense	distal	6	no	17.409	17.367	EPSD	COSMIC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	P06401	PGR	P17252	PRKCA	S162	R167W	167	Missense	distal	5	no	17.409	16.901	EPSD	COSMIC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	P06401	PGR	P17252	PRKCA	S162	M165I	165	Missense	distal	3	no	17.409	16.127	EPSD	COSMIC	16.704	Loss
AGC_PKC_PKCa_PRKCA_ST	P06401	PGR	P17252	PRKCA	S190	R187W	187	Missense	distal	-3	no	19.015	16.661	EPSD	COSMIC	16.704	Loss
AGC_PKC_PKCa_PRKCA_ST	P06401	PGR	P17252	PRKCA	S190	R187L	187	Missense	distal	-3	no	19.015	14.660	EPSD	COSMIC;CCLE	16.704	Loss
AGC_PKC_PKCa_PRKCA_ST	P06401	PGR	P17252	PRKCA	S273	E271K	271	Missense	proximal	-2	no	14.249	16.748	EPSD	COSMIC	16.704	Gain
AGC_PKC_PKCa_PRKCA_ST	P06401	PGR	P17252	PRKCA	S276	E271K	271	Missense	distal	-5	no	17.207	17.501	EPSD	COSMIC	16.704	Up-regulation
AGC_PKC_PKCa_PRKCA_ST	P06401	PGR	P17252	PRKCA	S276	A277V	277	Missense	proximal	1	no	17.207	17.360	EPSD	COSMIC	16.704	Up-regulation
AGC_PKC_PKCa_PRKCA_ST	P06401	PGR	P17252	PRKCA	S276	V283E	283	Missense	distal	7	no	17.207	17.214	EPSD	COSMIC	16.704	Up-regulation
AGC_PKC_PKCa_PRKCA_ST	P06401	PGR	P17252	PRKCA	S276	L282F	282	Missense	distal	6	no	17.207	17.176	EPSD	COSMIC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	P06401	PGR	P17252	PRKCA	S400	R399C	399	Missense	proximal	-1	no	17.185	14.525	PhosphoSitePlus	COSMIC	16.704	Loss
AGC_PKC_PKCa_PRKCA_ST	P06401	PGR	P17252	PRKCA	S400	R399S	399	Missense	proximal	-1	no	17.185	16.798	PhosphoSitePlus	COSMIC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	P06401	PGR	P17252	PRKCA	S400	R402C	402	Missense	proximal	2	no	17.185	12.835	PhosphoSitePlus	COSMIC	16.704	Loss
AGC_PKC_PKCa_PRKCA_ST	P06401	PGR	P17252	PRKCA	S400	P401L	401	Missense	proximal	1	no	17.185	17.612	PhosphoSitePlus	COSMIC	16.704	Up-regulation
AGC_PKC_PKCa_PRKCA_ST	P06401	PGR	P17252	PRKCA	S400	R402H	402	Missense	proximal	2	no	17.185	12.161	PhosphoSitePlus	COSMIC	16.704	Loss
AGC_PKC_PKCa_PRKCA_ST	Q8N556	AFAP1	P17252	PRKCA	S307	K306N	306	Missense	proximal	-1	no	22.757	22.155	EPSD	COSMIC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	Q8N556	AFAP1	P17252	PRKCA	S308	K306N	306	Missense	proximal	-2	no	17.992	16.424	EPSD	COSMIC	16.704	Loss
AGC_PKC_PKCa_PRKCA_ST	Q8N556	AFAP1	P17252	PRKCA	S510	D503V	503	Missense	distal	-7	no	17.799	17.795	EPSD	COSMIC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	Q8N556	AFAP1	P17252	PRKCA	S510	P505Q	505	Missense	distal	-5	no	17.799	17.748	EPSD	COSMIC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	Q8N556	AFAP1	P17252	PRKCA	S510	L511F	511	Missense	proximal	1	no	17.799	18.456	EPSD	COSMIC	16.704	Up-regulation
AGC_PKC_PKCa_PRKCA_ST	Q8N556	AFAP1	P17252	PRKCA	S510	G513D	513	Missense	distal	3	no	17.799	16.713	EPSD	COSMIC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	Q8N556	AFAP1	P17252	PRKCA	S510	G513C	513	Missense	distal	3	no	17.799	15.820	EPSD	COSMIC	16.704	Loss
AGC_PKC_PKCa_PRKCA_ST	Q8N556	AFAP1	P17252	PRKCA	T524	V518M	518	Missense	distal	-6	no	16.634	16.745	EPSD	COSMIC	16.704	Gain
AGC_PKC_PKCa_PRKCA_ST	Q8N556	AFAP1	P17252	PRKCA	S531	A537V	537	Missense	distal	6	no	16.713	16.594	EPSD	COSMIC	16.704	Loss
AGC_PKC_PKCa_PRKCA_ST	Q8N556	AFAP1	P17252	PRKCA	S531	G527E	527	Missense	distal	-4	no	16.713	16.119	EPSD	COSMIC	16.704	Loss
AGC_PKC_PKCa_PRKCA_ST	Q8N556	AFAP1	P17252	PRKCA	S548	Q552K	552	Missense	distal	4	no	18.033	18.421	EPSD	COSMIC	16.704	Up-regulation
AGC_PKC_PKCa_PRKCA_ST	Q8N556	AFAP1	P17252	PRKCA	S548	A551T	551	Missense	distal	3	no	18.033	17.794	EPSD	COSMIC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	Q8N556	AFAP1	P17252	PRKCA	S548	V542L	542	Missense	distal	-6	no	18.033	18.081	EPSD	COSMIC	16.704	Up-regulation
AGC_PKC_PKCa_PRKCA_ST	Q8N556	AFAP1	P17252	PRKCA	S548	A541T	541	Missense	distal	-7	no	18.033	18.028	EPSD	COSMIC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	Q8N556	AFAP1	P17252	PRKCA	S548	T546M	546	Missense	proximal	-2	no	18.033	18.945	EPSD	COSMIC	16.704	Up-regulation
AGC_PKC_PKCa_PRKCA_ST	Q96T49	PPP1R16B	P17252	PRKCA	S56	R61C	61	Missense	distal	5	no	19.577	18.845	EPSD	COSMIC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	Q96T49	PPP1R16B	P17252	PRKCA	S56	R60H	60	Missense	distal	4	no	19.577	19.294	EPSD	COSMIC;GDSC;CCLE	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	Q96T49	PPP1R16B	P17252	PRKCA	S56	G59S	59	Missense	distal	3	no	19.577	18.825	EPSD	COSMIC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	Q96T49	PPP1R16B	P17252	PRKCA	S56	T57M	57	Missense	proximal	1	no	19.577	19.862	EPSD	COSMIC	16.704	Up-regulation
AGC_PKC_PKCa_PRKCA_ST	Q96T49	PPP1R16B	P17252	PRKCA	S331	R334Q	334	Missense	distal	3	no	18.024	15.571	PhosphoSitePlus	COSMIC;GDSC;CCLE	16.704	Loss
AGC_PKC_PKCa_PRKCA_ST	Q96T49	PPP1R16B	P17252	PRKCA	S331	S331F	331	Missense	central	0	yes	18.024	0.000	PhosphoSitePlus	COSMIC	16.704	Loss
AGC_PKC_PKCa_PRKCA_ST	Q96T49	PPP1R16B	P17252	PRKCA	S350	S350G	350	Missense	central	0	yes	18.950	0.000	EPSD	COSMIC	16.704	Loss
AGC_PKC_PKCa_PRKCA_ST	Q96T49	PPP1R16B	P17252	PRKCA	S350	R348Q	348	Missense	proximal	-2	no	18.950	17.191	EPSD	COSMIC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	Q96T49	PPP1R16B	P17252	PRKCA	S350	D353Y	353	Missense	distal	3	no	18.950	18.407	EPSD	COSMIC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	Q96T49	PPP1R16B	P17252	PRKCA	S350	S350N	350	Missense	central	0	yes	18.950	0.000	EPSD	COSMIC	16.704	Loss
AGC_PKC_PKCa_PRKCA_ST	Q96T49	PPP1R16B	P17252	PRKCA	S350	R347Q	347	Missense	distal	-3	no	18.950	16.092	EPSD	COSMIC	16.704	Loss
AGC_PKC_PKCa_PRKCA_ST	Q8TD43	TRPM4	P17252	PRKCA	S94	T97M	97	Missense	distal	3	no	20.175	20.743	EPSD	COSMIC	16.704	Up-regulation
AGC_PKC_PKCa_PRKCA_ST	Q8TD43	TRPM4	P17252	PRKCA	S94	A101T	101	Missense	distal	7	no	20.175	20.183	EPSD	COSMIC	16.704	Up-regulation
AGC_PKC_PKCa_PRKCA_ST	Q8TD43	TRPM4	P17252	PRKCA	S177	G179R	179	Missense	proximal	2	no	15.489	20.734	EPSD	COSMIC	16.704	Gain
AGC_PKC_PKCa_PRKCA_ST	Q8TD43	TRPM4	P17252	PRKCA	S255	R248C	248	Missense	distal	-7	no	19.561	19.542	EPSD	COSMIC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	Q8TD43	TRPM4	P17252	PRKCA	S255	R250H	250	Missense	distal	-5	no	19.561	19.206	EPSD	COSMIC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	Q8TD43	TRPM4	P17252	PRKCA	S541	T545I	545	Missense	distal	4	no	18.869	17.856	EPSD	COSMIC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	Q8TD43	TRPM4	P17252	PRKCA	S1098	P1101L	1101	Missense	distal	3	no	19.660	18.954	EPSD	COSMIC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	Q8TD43	TRPM4	P17252	PRKCA	S1098	R1097Q	1097	Missense	proximal	-1	no	19.660	18.843	EPSD	COSMIC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	Q8TD43	TRPM4	P17252	PRKCA	S1143	E1142K	1142	Missense	proximal	-1	no	16.763	17.189	EPSD	COSMIC;CCLE	16.704	Up-regulation
AGC_PKC_PKCa_PRKCA_ST	Q8TD43	TRPM4	P17252	PRKCA	S1143	R1136C	1136	Missense	distal	-7	no	16.763	16.744	EPSD	COSMIC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	Q8TD43	TRPM4	P17252	PRKCA	S1143	S1145F	1145	Missense	proximal	2	no	16.763	17.080	EPSD	COSMIC	16.704	Up-regulation
AGC_PKC_PKCa_PRKCA_ST	Q8TD43	TRPM4	P17252	PRKCA	S1143	A1137T	1137	Missense	distal	-6	no	16.763	16.674	EPSD	COSMIC	16.704	Loss
AGC_PKC_PKCa_PRKCA_ST	Q8TD43	TRPM4	P17252	PRKCA	S1145	E1142K	1142	Missense	distal	-3	no	15.257	18.169	EPSD;PhosphoSitePlus	COSMIC;CCLE	16.704	Gain
AGC_PKC_PKCa_PRKCA_ST	Q8TD43	TRPM4	P17252	PRKCA	S1152	S1145F	1145	Missense	distal	-7	no	20.781	20.773	PhosphoSitePlus;EPSD	COSMIC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	Q969H0	FBXW7	P17252	PRKCA	S10	K11R	11	Missense	proximal	1	no	25.231	25.193	PhosphoSitePlus;EPSD	COSMIC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	Q969H0	FBXW7	P17252	PRKCA	S10	S7Y	7	Missense	distal	-3	no	25.231	23.541	PhosphoSitePlus;EPSD	COSMIC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	Q969H0	FBXW7	P17252	PRKCA	S10	L6F	6	Missense	distal	-4	no	25.231	25.604	PhosphoSitePlus;EPSD	COSMIC	16.704	Up-regulation
AGC_PKC_PKCa_PRKCA_ST	Q969H0	FBXW7	P17252	PRKCA	S10	S7F	7	Missense	distal	-3	no	25.231	25.480	PhosphoSitePlus;EPSD	COSMIC	16.704	Up-regulation
AGC_PKC_PKCa_PRKCA_ST	Q969H0	FBXW7	P17252	PRKCA	S10	Q3E	3	Missense	distal	-7	no	25.231	25.226	PhosphoSitePlus;EPSD	COSMIC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	Q969H0	FBXW7	P17252	PRKCA	S10	R13L	13	Missense	distal	3	no	25.231	22.993	PhosphoSitePlus;EPSD	COSMIC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	Q969H0	FBXW7	P17252	PRKCA	S18	K11R	11	Missense	distal	-7	no	20.808	20.813	EPSD;PhosphoSitePlus	COSMIC	16.704	Up-regulation
AGC_PKC_PKCa_PRKCA_ST	Q969H0	FBXW7	P17252	PRKCA	S18	R13L	13	Missense	distal	-5	no	20.808	20.680	EPSD;PhosphoSitePlus	COSMIC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	Q969H0	FBXW7	P17252	PRKCA	S227	R223L	223	Missense	distal	-4	no	19.658	19.034	EPSD	COSMIC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	Q969H0	FBXW7	P17252	PRKCA	S227	P230L	230	Missense	distal	3	no	19.658	18.951	EPSD	COSMIC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	Q969H0	FBXW7	P17252	PRKCA	S227	R223C	223	Missense	distal	-4	no	19.658	18.315	EPSD	COSMIC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	Q969H0	FBXW7	P17252	PRKCA	S227	R222Q	222	Missense	distal	-5	no	19.658	19.506	EPSD	COSMIC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	Q969H0	FBXW7	P17252	PRKCA	S227	L234M	234	Missense	distal	7	no	19.658	19.666	EPSD	COSMIC	16.704	Up-regulation
AGC_PKC_PKCa_PRKCA_ST	Q969H0	FBXW7	P17252	PRKCA	S372	E369G	369	Missense	distal	-3	no	15.761	17.438	EPSD	COSMIC	16.704	Gain
AGC_PKC_PKCa_PRKCA_ST	P11473	VDR	P17252	PRKCA	S7	P11H	11	Missense	distal	4	no	16.584	16.748	EPSD	COSMIC	16.704	Gain
AGC_PKC_PKCa_PRKCA_ST	P11473	VDR	P17252	PRKCA	S51	M52R	52	Missense	proximal	1	no	25.800	26.361	PhosphoSitePlus	COSMIC	16.704	Up-regulation
AGC_PKC_PKCa_PRKCA_ST	P11473	VDR	P17252	PRKCA	S51	M52I	52	Missense	proximal	1	no	25.800	26.850	PhosphoSitePlus	COSMIC	16.704	Up-regulation
AGC_PKC_PKCa_PRKCA_ST	P11473	VDR	P17252	PRKCA	S51	G46R	46	Missense	distal	-5	no	25.800	26.090	PhosphoSitePlus	COSMIC	16.704	Up-regulation
AGC_PKC_PKCa_PRKCA_ST	P11473	VDR	P17252	PRKCA	S51	M52T	52	Missense	proximal	1	no	25.800	25.515	PhosphoSitePlus	COSMIC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	P11473	VDR	P17252	PRKCA	S51	K55N	55	Missense	distal	4	no	25.800	24.673	PhosphoSitePlus	COSMIC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	P11473	VDR	P17252	PRKCA	S51	R50Q	50	Missense	proximal	-1	no	25.800	24.982	PhosphoSitePlus	COSMIC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	P11473	VDR	P17252	PRKCA	S51	A56V	56	Missense	distal	5	no	25.800	25.416	PhosphoSitePlus	COSMIC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	Q9NPC2	KCNK9	P17252	PRKCA	T134	R137H	137	Missense	distal	3	no	17.526	16.814	EPSD	COSMIC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	Q9NPC2	KCNK9	P17252	PRKCA	T134	E130K	130	Missense	distal	-4	no	17.526	18.257	EPSD	COSMIC	16.704	Up-regulation
AGC_PKC_PKCa_PRKCA_ST	Q9NPC2	KCNK9	P17252	PRKCA	S317	P314S	314	Missense	distal	-3	no	15.824	16.803	EPSD	COSMIC	16.704	Gain
AGC_PKC_PKCa_PRKCA_ST	Q9NPC2	KCNK9	P17252	PRKCA	T341	F347Y	347	Missense	distal	6	no	17.927	17.987	PhosphoSitePlus	COSMIC	16.704	Up-regulation
AGC_PKC_PKCa_PRKCA_ST	Q9NPC2	KCNK9	P17252	PRKCA	S373	R370L	370	Missense	distal	-3	no	16.743	12.388	EPSD	COSMIC	16.704	Loss
AGC_PKC_PKCa_PRKCA_ST	Q9NPC2	KCNK9	P17252	PRKCA	S373	R371W	371	Missense	proximal	-2	no	16.743	14.746	EPSD	COSMIC	16.704	Loss
AGC_PKC_PKCa_PRKCA_ST	Q9NPC2	KCNK9	P17252	PRKCA	S373	R366K	366	Missense	distal	-7	no	16.743	16.738	EPSD	COSMIC;GDSC;CCLE	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	Q9NPC2	KCNK9	P17252	PRKCA	S373	R371L	371	Missense	proximal	-2	no	16.743	14.055	EPSD	COSMIC	16.704	Loss
AGC_PKC_PKCa_PRKCA_ST	Q14184	DOC2B	P17252	PRKCA	T211	E205K	205	Missense	distal	-6	no	18.057	18.125	EPSD	COSMIC	16.704	Up-regulation
AGC_PKC_PKCa_PRKCA_ST	Q12959	DLG1	P17252	PRKCA	S23	R19G	19	Missense	distal	-4	no	18.137	18.035	EPSD	COSMIC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	Q12959	DLG1	P17252	PRKCA	S23	R19H	19	Missense	distal	-4	no	18.137	17.563	EPSD	COSMIC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	Q12959	DLG1	P17252	PRKCA	S232	F236V	236	Missense	distal	4	no	18.156	17.196	EPSD	COSMIC;CCLE	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	Q12959	DLG1	P17252	PRKCA	S232	A239T	239	Missense	distal	7	no	18.156	18.165	EPSD	COSMIC	16.704	Up-regulation
AGC_PKC_PKCa_PRKCA_ST	Q12959	DLG1	P17252	PRKCA	S232	S232L	232	Missense	central	0	yes	18.156	0.000	EPSD	COSMIC	16.704	Loss
AGC_PKC_PKCa_PRKCA_ST	Q12959	DLG1	P17252	PRKCA	S435	Q439L	439	Missense	distal	4	no	17.292	16.471	EPSD	COSMIC	16.704	Loss
AGC_PKC_PKCa_PRKCA_ST	Q12959	DLG1	P17252	PRKCA	S575	Q580E	580	Missense	distal	5	no	18.992	18.730	EPSD	COSMIC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	Q12959	DLG1	P17252	PRKCA	S575	S573G	573	Missense	proximal	-2	no	18.992	19.422	EPSD	COSMIC	16.704	Up-regulation
AGC_PKC_PKCa_PRKCA_ST	Q12959	DLG1	P17252	PRKCA	S575	I569V	569	Missense	distal	-6	no	18.992	18.975	EPSD	COSMIC;GDSC;CCLE	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	Q12959	DLG1	P17252	PRKCA	S575	R577Q	577	Missense	proximal	2	no	18.992	15.158	EPSD	COSMIC	16.704	Loss
AGC_PKC_PKCa_PRKCA_ST	Q12959	DLG1	P17252	PRKCA	S575	L576F	576	Missense	proximal	1	no	18.992	19.650	EPSD	COSMIC	16.704	Up-regulation
AGC_PKC_PKCa_PRKCA_ST	Q12959	DLG1	P17252	PRKCA	S579	Q580E	580	Missense	proximal	1	no	21.263	19.813	EPSD	COSMIC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	Q12959	DLG1	P17252	PRKCA	S579	S573G	573	Missense	distal	-6	no	21.263	21.229	EPSD	COSMIC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	Q12959	DLG1	P17252	PRKCA	S579	R577Q	577	Missense	proximal	-2	no	21.263	19.504	EPSD	COSMIC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	Q12959	DLG1	P17252	PRKCA	S579	Y585C	585	Missense	distal	6	no	21.263	21.077	EPSD	COSMIC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	Q12959	DLG1	P17252	PRKCA	S579	V586D	586	Missense	distal	7	no	21.263	21.322	EPSD	COSMIC	16.704	Up-regulation
AGC_PKC_PKCa_PRKCA_ST	Q12959	DLG1	P17252	PRKCA	S579	L576F	576	Missense	distal	-3	no	21.263	22.998	EPSD	COSMIC	16.704	Up-regulation
AGC_PKC_PKCa_PRKCA_ST	Q12959	DLG1	P17252	PRKCA	S583	Q580E	580	Missense	distal	-3	no	18.178	16.097	EPSD	COSMIC	16.704	Loss
AGC_PKC_PKCa_PRKCA_ST	Q12959	DLG1	P17252	PRKCA	S583	R577Q	577	Missense	distal	-6	no	18.178	18.035	EPSD	COSMIC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	Q12959	DLG1	P17252	PRKCA	S583	Y585C	585	Missense	proximal	2	no	18.178	18.323	EPSD	COSMIC	16.704	Up-regulation
AGC_PKC_PKCa_PRKCA_ST	Q12959	DLG1	P17252	PRKCA	S583	R587G	587	Missense	distal	4	no	18.178	17.574	EPSD	COSMIC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	Q12959	DLG1	P17252	PRKCA	S583	V586D	586	Missense	distal	3	no	18.178	18.307	EPSD	COSMIC	16.704	Up-regulation
AGC_PKC_PKCa_PRKCA_ST	Q12959	DLG1	P17252	PRKCA	S583	L576F	576	Missense	distal	-7	no	18.178	18.175	EPSD	COSMIC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	Q12959	DLG1	P17252	PRKCA	S583	R587K	587	Missense	distal	4	no	18.178	18.349	EPSD	COSMIC	16.704	Up-regulation
AGC_PKC_PKCa_PRKCA_ST	Q12959	DLG1	P17252	PRKCA	S583	L589I	589	Missense	distal	6	no	18.178	18.154	EPSD	COSMIC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	Q12959	DLG1	P17252	PRKCA	S643	D636N	636	Missense	distal	-7	no	18.485	18.484	EPSD	COSMIC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	Q12959	DLG1	P17252	PRKCA	S643	P642S	642	Missense	proximal	-1	no	18.485	18.785	EPSD	COSMIC	16.704	Up-regulation
AGC_PKC_PKCa_PRKCA_ST	Q12959	DLG1	P17252	PRKCA	T657	E651Q	651	Missense	distal	-6	no	20.821	20.753	PhosphoSitePlus	COSMIC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	Q12959	DLG1	P17252	PRKCA	T657	F660S	660	Missense	distal	3	no	20.821	21.334	PhosphoSitePlus	COSMIC	16.704	Up-regulation
AGC_PKC_PKCa_PRKCA_ST	Q12959	DLG1	P17252	PRKCA	T657	A653D	653	Missense	distal	-4	no	20.821	20.056	PhosphoSitePlus	COSMIC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	Q12959	DLG1	P17252	PRKCA	T657	R654T	654	Missense	distal	-3	no	20.821	16.658	PhosphoSitePlus	COSMIC	16.704	Loss
AGC_PKC_PKCa_PRKCA_ST	Q12959	DLG1	P17252	PRKCA	S692	S689G	689	Missense	distal	-3	no	18.890	18.498	EPSD	COSMIC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	Q12959	DLG1	P17252	PRKCA	S692	E698K	698	Missense	distal	6	no	18.890	18.984	EPSD	COSMIC	16.704	Up-regulation
AGC_PKC_PKCa_PRKCA_ST	Q12959	DLG1	P17252	PRKCA	S692	E698V	698	Missense	distal	6	no	18.890	18.836	EPSD	COSMIC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	Q12959	DLG1	P17252	PRKCA	S692	A686D	686	Missense	distal	-6	no	18.890	18.842	EPSD	COSMIC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	Q12959	DLG1	P17252	PRKCA	S692	Q696E	696	Missense	distal	4	no	18.890	18.739	EPSD	COSMIC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	Q12959	DLG1	P17252	PRKCA	S692	Y693C	693	Missense	proximal	1	no	18.890	16.417	EPSD	COSMIC	16.704	Loss
AGC_PKC_PKCa_PRKCA_ST	Q12959	DLG1	P17252	PRKCA	S792	Q794R	794	Missense	proximal	2	no	13.057	16.891	EPSD	COSMIC	16.704	Gain
AGC_PKC_PKCa_PRKCA_ST	Q12959	DLG1	P17252	PRKCA	S795	Q794R	794	Missense	proximal	-1	no	19.268	20.086	EPSD	COSMIC	16.704	Up-regulation
AGC_PKC_PKCa_PRKCA_ST	Q12959	DLG1	P17252	PRKCA	S795	R797Q	797	Missense	proximal	2	no	19.268	15.434	EPSD	COSMIC	16.704	Loss
AGC_PKC_PKCa_PRKCA_ST	Q12959	DLG1	P17252	PRKCA	S795	V796E	796	Missense	proximal	1	no	19.268	17.924	EPSD	COSMIC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	Q12959	DLG1	P17252	PRKCA	S795	V793A	793	Missense	proximal	-2	no	19.268	19.025	EPSD	COSMIC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	Q12959	DLG1	P17252	PRKCA	S795	Y789C	789	Missense	distal	-6	no	19.268	19.026	EPSD	COSMIC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	Q12959	DLG1	P17252	PRKCA	S795	E798Q	798	Missense	distal	3	no	19.268	18.054	EPSD	COSMIC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	Q5NUL3	FFAR4	P17252	PRKCA	S253	K251T	251	Missense	proximal	-2	no	19.689	18.423	EPSD	COSMIC;GDSC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	Q5NUL3	FFAR4	P17252	PRKCA	S253	R254C	254	Missense	proximal	1	no	19.689	16.853	EPSD	COSMIC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	Q5NUL3	FFAR4	P17252	PRKCA	S253	R254H	254	Missense	proximal	1	no	19.689	18.876	EPSD	COSMIC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	P41180	CASR	P17252	PRKCA	T888	A884V	884	Missense	distal	-4	no	17.986	17.427	PhosphoSitePlus	COSMIC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	P41180	CASR	P17252	PRKCA	T888	A887V	887	Missense	proximal	-1	no	17.986	17.082	PhosphoSitePlus	COSMIC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	P41180	CASR	P17252	PRKCA	S895	R898W	898	Missense	distal	3	no	19.647	16.713	EPSD	COSMIC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	P41180	CASR	P17252	PRKCA	S895	R898Q	898	Missense	distal	3	no	19.647	17.194	EPSD	COSMIC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	P41180	CASR	P17252	PRKCA	S899	R898W	898	Missense	proximal	-1	no	17.285	15.700	EPSD	COSMIC	16.704	Loss
AGC_PKC_PKCa_PRKCA_ST	P41180	CASR	P17252	PRKCA	S899	R898Q	898	Missense	proximal	-1	no	17.285	16.467	EPSD	COSMIC	16.704	Loss
AGC_PKC_PKCa_PRKCA_ST	P41180	CASR	P17252	PRKCA	S900	R898W	898	Missense	proximal	-2	no	17.164	15.167	EPSD	COSMIC	16.704	Loss
AGC_PKC_PKCa_PRKCA_ST	P41180	CASR	P17252	PRKCA	S900	G907V	907	Missense	distal	7	no	17.164	17.086	EPSD	COSMIC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	P41180	CASR	P17252	PRKCA	S900	R898Q	898	Missense	proximal	-2	no	17.164	15.405	EPSD	COSMIC	16.704	Loss
AGC_PKC_PKCa_PRKCA_ST	P41180	CASR	P17252	PRKCA	S901	R898W	898	Missense	distal	-3	no	16.908	14.554	EPSD	COSMIC	16.704	Loss
AGC_PKC_PKCa_PRKCA_ST	P41180	CASR	P17252	PRKCA	S901	G907V	907	Missense	distal	6	no	16.908	16.896	EPSD	COSMIC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	P41180	CASR	P17252	PRKCA	S901	R898Q	898	Missense	distal	-3	no	16.908	14.050	EPSD	COSMIC	16.704	Loss
AGC_PKC_PKCa_PRKCA_ST	P41180	CASR	P17252	PRKCA	S915	S912F	912	Missense	distal	-3	no	16.458	16.707	EPSD	COSMIC	16.704	Gain
AGC_PKC_PKCa_PRKCA_ST	P41180	CASR	P17252	PRKCA	S915	N919T	919	Missense	distal	4	no	16.458	16.737	EPSD	COSMIC	16.704	Gain
AGC_PKC_PKCa_PRKCA_ST	Q04206	RELA	P17252	PRKCA	S276	D277N	277	Missense	proximal	1	no	20.996	21.468	EPSD	COSMIC;CCLE	16.704	Up-regulation
AGC_PKC_PKCa_PRKCA_ST	Q04206	RELA	P17252	PRKCA	S276	R274Q	274	Missense	proximal	-2	no	20.996	19.237	EPSD	COSMIC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	Q04206	RELA	P17252	PRKCA	S276	R278Q	278	Missense	proximal	2	no	20.996	17.162	EPSD	COSMIC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	Q8NFA2	NOXO1	P17252	PRKCA	S159	Q166R	166	Missense	distal	7	no	17.846	17.850	EPSD	COSMIC	16.704	Up-regulation
AGC_PKC_PKCa_PRKCA_ST	Q8NFA2	NOXO1	P17252	PRKCA	S159	L158F	158	Missense	proximal	-1	no	17.846	17.558	EPSD	COSMIC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	Q8NFA2	NOXO1	P17252	PRKCA	S159	A154T	154	Missense	distal	-5	no	17.846	18.226	EPSD	COSMIC	16.704	Up-regulation
AGC_PKC_PKCa_PRKCA_ST	Q8NFA2	NOXO1	P17252	PRKCA	T346	R349Q	349	Missense	distal	3	no	17.662	15.209	EPSD	COSMIC	16.704	Loss
AGC_PKC_PKCa_PRKCA_ST	Q99623	PHB2	P17252	PRKCA	S39	V43M	43	Missense	distal	4	no	17.637	19.009	PhosphoSitePlus	COSMIC	16.704	Up-regulation
AGC_PKC_PKCa_PRKCA_ST	Q99623	PHB2	P17252	PRKCA	S105	R107Q	107	Missense	proximal	2	no	16.893	13.059	EPSD	COSMIC	16.704	Loss
AGC_PKC_PKCa_PRKCA_ST	Q99623	PHB2	P17252	PRKCA	T169	R166W	166	Missense	distal	-3	no	19.559	17.205	EPSD	COSMIC;CCLE	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	Q99623	PHB2	P17252	PRKCA	T169	R165C	165	Missense	distal	-4	no	19.559	18.215	EPSD	COSMIC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	P16070	CD44	P17252	PRKCA	S672	Q678H	678	Missense	distal	6	no	18.340	18.386	PhosphoSitePlus	COSMIC	16.704	Up-regulation
AGC_PKC_PKCa_PRKCA_ST	P16070	CD44	P17252	PRKCA	S672	R673Q	673	Missense	proximal	1	no	18.340	18.224	PhosphoSitePlus	COSMIC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	O14939	PLD2	P17252	PRKCA	T100	H106D	106	Missense	distal	6	no	17.878	17.865	EPSD	COSMIC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	O14939	PLD2	P17252	PRKCA	T100	R105L	105	Missense	distal	5	no	17.878	17.545	EPSD	COSMIC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	O14939	PLD2	P17252	PRKCA	T100	R105H	105	Missense	distal	5	no	17.878	17.618	EPSD	COSMIC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	O14939	PLD2	P17252	PRKCA	S213	R210Q	210	Missense	distal	-3	no	19.804	16.947	EPSD	COSMIC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	O14939	PLD2	P17252	PRKCA	T274	G279S	279	Missense	distal	5	no	17.364	17.504	EPSD	COSMIC	16.704	Up-regulation
AGC_PKC_PKCa_PRKCA_ST	O14939	PLD2	P17252	PRKCA	S416	S416I	416	Missense	central	0	yes	19.446	0.000	EPSD	COSMIC	16.704	Loss
AGC_PKC_PKCa_PRKCA_ST	O14939	PLD2	P17252	PRKCA	T488	P487A	487	Missense	proximal	-1	no	16.907	16.648	EPSD	COSMIC	16.704	Loss
AGC_PKC_PKCa_PRKCA_ST	O14939	PLD2	P17252	PRKCA	T488	R490H	490	Missense	proximal	2	no	16.907	11.883	EPSD	COSMIC;CCLE	16.704	Loss
AGC_PKC_PKCa_PRKCA_ST	O14939	PLD2	P17252	PRKCA	S814	Q807E	807	Missense	distal	-7	no	18.723	18.718	EPSD	COSMIC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	O14939	PLD2	P17252	PRKCA	S814	L813R	813	Missense	proximal	-1	no	18.723	19.529	EPSD	COSMIC	16.704	Up-regulation
AGC_PKC_PKCa_PRKCA_ST	O14939	PLD2	P17252	PRKCA	S814	H818R	818	Missense	distal	4	no	18.723	19.005	EPSD	COSMIC	16.704	Up-regulation
AGC_PKC_PKCa_PRKCA_ST	Q5JVS0	HABP4	P17252	PRKCA	T375	R379Q	379	Missense	distal	4	no	18.122	17.904	PhosphoSitePlus;EPSD	COSMIC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	Q5JVS0	HABP4	P17252	PRKCA	T375	R379W	379	Missense	distal	4	no	18.122	16.586	PhosphoSitePlus;EPSD	COSMIC;GDSC	16.704	Loss
AGC_PKC_PKCa_PRKCA_ST	Q5JVS0	HABP4	P17252	PRKCA	T375	G377A	377	Missense	proximal	2	no	18.122	18.669	PhosphoSitePlus;EPSD	COSMIC	16.704	Up-regulation
AGC_PKC_PKCa_PRKCA_ST	Q9BZL6	PRKD2	P17252	PRKCA	S183	N187K	187	Missense	distal	4	no	16.203	17.330	EPSD	COSMIC	16.704	Gain
AGC_PKC_PKCa_PRKCA_ST	Q9BZL6	PRKD2	P17252	PRKCA	S197	S203I	203	Missense	distal	6	no	17.772	17.738	EPSD	COSMIC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	Q9BZL6	PRKD2	P17252	PRKCA	S197	R195S	195	Missense	proximal	-2	no	17.772	14.470	EPSD	COSMIC	16.704	Loss
AGC_PKC_PKCa_PRKCA_ST	Q9BZL6	PRKD2	P17252	PRKCA	S197	A202V	202	Missense	distal	5	no	17.772	17.388	EPSD	COSMIC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	Q9BZL6	PRKD2	P17252	PRKCA	S197	S203C	203	Missense	distal	6	no	17.772	17.604	EPSD	COSMIC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	Q9BZL6	PRKD2	P17252	PRKCA	S198	S203I	203	Missense	distal	5	no	19.167	18.974	EPSD	COSMIC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	Q9BZL6	PRKD2	P17252	PRKCA	S198	R195S	195	Missense	distal	-3	no	19.167	16.297	EPSD	COSMIC	16.704	Loss
AGC_PKC_PKCa_PRKCA_ST	Q9BZL6	PRKD2	P17252	PRKCA	S198	A202V	202	Missense	distal	4	no	19.167	17.829	EPSD	COSMIC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	Q9BZL6	PRKD2	P17252	PRKCA	S198	S203C	203	Missense	distal	5	no	19.167	18.577	EPSD	COSMIC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	Q9BZL6	PRKD2	P17252	PRKCA	S206	S203I	203	Missense	distal	-3	no	18.452	16.835	EPSD	COSMIC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	Q9BZL6	PRKD2	P17252	PRKCA	S206	A202V	202	Missense	distal	-4	no	18.452	17.893	EPSD	COSMIC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	Q9BZL6	PRKD2	P17252	PRKCA	S206	S203C	203	Missense	distal	-3	no	18.452	18.583	EPSD	COSMIC	16.704	Up-regulation
AGC_PKC_PKCa_PRKCA_ST	Q9BZL6	PRKD2	P17252	PRKCA	S236	S237F	237	Missense	proximal	1	no	16.389	17.873	EPSD	COSMIC	16.704	Gain
AGC_PKC_PKCa_PRKCA_ST	Q9BZL6	PRKD2	P17252	PRKCA	S387	R389L	389	Missense	proximal	2	no	20.777	15.790	EPSD	COSMIC	16.704	Loss
AGC_PKC_PKCa_PRKCA_ST	Q9BZL6	PRKD2	P17252	PRKCA	S387	V385E	385	Missense	proximal	-2	no	20.777	19.492	EPSD	COSMIC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	Q9BZL6	PRKD2	P17252	PRKCA	S387	Q386K	386	Missense	proximal	-1	no	20.777	21.651	EPSD	COSMIC	16.704	Up-regulation
AGC_PKC_PKCa_PRKCA_ST	Q9BZL6	PRKD2	P17252	PRKCA	S387	T391M	391	Missense	distal	4	no	20.777	21.258	EPSD	COSMIC	16.704	Up-regulation
AGC_PKC_PKCa_PRKCA_ST	Q9BZL6	PRKD2	P17252	PRKCA	T391	T397N	397	Missense	distal	6	no	22.239	22.185	EPSD	COSMIC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	Q9BZL6	PRKD2	P17252	PRKCA	T391	R389L	389	Missense	proximal	-2	no	22.239	19.551	EPSD	COSMIC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	Q9BZL6	PRKD2	P17252	PRKCA	T391	V385E	385	Missense	distal	-6	no	22.239	22.351	EPSD	COSMIC	16.704	Up-regulation
AGC_PKC_PKCa_PRKCA_ST	Q9BZL6	PRKD2	P17252	PRKCA	T391	Q386K	386	Missense	distal	-5	no	22.239	22.378	EPSD	COSMIC	16.704	Up-regulation
AGC_PKC_PKCa_PRKCA_ST	Q9BZL6	PRKD2	P17252	PRKCA	T391	T391M	391	Missense	central	0	yes	22.239	0.000	EPSD	COSMIC	16.704	Loss
AGC_PKC_PKCa_PRKCA_ST	Q9BZL6	PRKD2	P17252	PRKCA	T392	T397N	397	Missense	distal	5	no	17.971	17.926	EPSD	COSMIC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	Q9BZL6	PRKD2	P17252	PRKCA	T392	L399P	399	Missense	distal	7	no	17.971	18.005	EPSD	COSMIC	16.704	Up-regulation
AGC_PKC_PKCa_PRKCA_ST	Q9BZL6	PRKD2	P17252	PRKCA	T392	R389L	389	Missense	distal	-3	no	17.971	13.616	EPSD	COSMIC	16.704	Loss
AGC_PKC_PKCa_PRKCA_ST	Q9BZL6	PRKD2	P17252	PRKCA	T392	V385E	385	Missense	distal	-7	no	17.971	17.972	EPSD	COSMIC	16.704	Up-regulation
AGC_PKC_PKCa_PRKCA_ST	Q9BZL6	PRKD2	P17252	PRKCA	T392	Q386K	386	Missense	distal	-6	no	17.971	18.107	EPSD	COSMIC	16.704	Up-regulation
AGC_PKC_PKCa_PRKCA_ST	Q9BZL6	PRKD2	P17252	PRKCA	T392	T391M	391	Missense	proximal	-1	no	17.971	19.009	EPSD	COSMIC	16.704	Up-regulation
AGC_PKC_PKCa_PRKCA_ST	Q9BZL6	PRKD2	P17252	PRKCA	T412	D411N	411	Missense	proximal	-1	no	17.328	17.665	EPSD	COSMIC	16.704	Up-regulation
AGC_PKC_PKCa_PRKCA_ST	Q9BZL6	PRKD2	P17252	PRKCA	S529	A523T	523	Missense	distal	-6	no	16.922	16.833	EPSD	COSMIC;GDSC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	Q9BZL6	PRKD2	P17252	PRKCA	S706	F707L	707	Missense	proximal	1	no	20.420	19.762	EPSD;PhosphoSitePlus	COSMIC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	Q9BZL6	PRKD2	P17252	PRKCA	S706	A699V	699	Missense	distal	-7	no	20.420	20.410	EPSD;PhosphoSitePlus	COSMIC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	Q9BZL6	PRKD2	P17252	PRKCA	S706	G703D	703	Missense	distal	-3	no	20.420	18.640	EPSD;PhosphoSitePlus	COSMIC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	Q9BZL6	PRKD2	P17252	PRKCA	S706	R700H	700	Missense	distal	-6	no	20.420	20.352	EPSD;PhosphoSitePlus	COSMIC;CCLE	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	Q9BZL6	PRKD2	P17252	PRKCA	S706	G713R	713	Missense	distal	7	no	20.420	20.444	EPSD;PhosphoSitePlus	COSMIC	16.704	Up-regulation
AGC_PKC_PKCa_PRKCA_ST	Q9BZL6	PRKD2	P17252	PRKCA	S706	G713E	713	Missense	distal	7	no	20.420	20.349	EPSD;PhosphoSitePlus	COSMIC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	Q9BZL6	PRKD2	P17252	PRKCA	S710	F707L	707	Missense	distal	-3	no	20.269	18.534	EPSD;PhosphoSitePlus	COSMIC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	Q9BZL6	PRKD2	P17252	PRKCA	S710	G713R	713	Missense	distal	3	no	20.269	20.908	EPSD;PhosphoSitePlus	COSMIC	16.704	Up-regulation
AGC_PKC_PKCa_PRKCA_ST	Q9BZL6	PRKD2	P17252	PRKCA	S710	G713E	713	Missense	distal	3	no	20.269	19.670	EPSD;PhosphoSitePlus	COSMIC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	Q13002	GRIK2	P17252	PRKCA	S361	G356R	356	Missense	distal	-5	no	16.683	16.973	EPSD	COSMIC	16.704	Gain
AGC_PKC_PKCa_PRKCA_ST	Q13002	GRIK2	P17252	PRKCA	T376	N378K	378	Missense	proximal	2	no	14.308	19.257	EPSD	COSMIC;CCLE	16.704	Gain
AGC_PKC_PKCa_PRKCA_ST	Q13002	GRIK2	P17252	PRKCA	S416	G419E	419	Missense	distal	3	no	21.070	20.471	EPSD	COSMIC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	Q13002	GRIK2	P17252	PRKCA	S416	T414K	414	Missense	proximal	-2	no	21.070	22.336	EPSD	COSMIC	16.704	Up-regulation
AGC_PKC_PKCa_PRKCA_ST	Q13002	GRIK2	P17252	PRKCA	S416	A422G	422	Missense	distal	6	no	21.070	20.962	EPSD	COSMIC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	Q13002	GRIK2	P17252	PRKCA	S666	P667S	667	Missense	proximal	1	no	18.976	18.577	EPSD	COSMIC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	Q13002	GRIK2	P17252	PRKCA	S666	R663C	663	Missense	distal	-3	no	18.976	16.237	EPSD	COSMIC;CCLE	16.704	Loss
AGC_PKC_PKCa_PRKCA_ST	Q13002	GRIK2	P17252	PRKCA	S666	E665K	665	Missense	proximal	-1	no	18.976	19.402	EPSD	COSMIC	16.704	Up-regulation
AGC_PKC_PKCa_PRKCA_ST	Q13002	GRIK2	P17252	PRKCA	S666	E662D	662	Missense	distal	-4	no	18.976	18.800	EPSD	COSMIC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	Q13002	GRIK2	P17252	PRKCA	S666	L659Q	659	Missense	distal	-7	no	18.976	18.979	EPSD	COSMIC;GDSC;CCLE	16.704	Up-regulation
AGC_PKC_PKCa_PRKCA_ST	Q13002	GRIK2	P17252	PRKCA	S666	R663H	663	Missense	distal	-3	no	18.976	15.120	EPSD	COSMIC;CCLE	16.704	Loss
AGC_PKC_PKCa_PRKCA_ST	Q13002	GRIK2	P17252	PRKCA	S697	T692S	692	Missense	distal	-5	no	17.665	17.337	EPSD	COSMIC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	Q13002	GRIK2	P17252	PRKCA	S697	T692A	692	Missense	distal	-5	no	17.665	17.284	EPSD	COSMIC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	Q13002	GRIK2	P17252	PRKCA	S697	I699T	699	Missense	proximal	2	no	17.665	17.886	EPSD	COSMIC;GDSC;CCLE	16.704	Up-regulation
AGC_PKC_PKCa_PRKCA_ST	Q13002	GRIK2	P17252	PRKCA	S697	F693Y	693	Missense	distal	-4	no	17.665	17.529	EPSD	COSMIC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	Q13002	GRIK2	P17252	PRKCA	S697	K695M	695	Missense	proximal	-2	no	17.665	17.311	EPSD	COSMIC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	Q13002	GRIK2	P17252	PRKCA	S846	A850S	850	Missense	distal	4	no	19.804	19.787	EPSD	COSMIC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	Q13002	GRIK2	P17252	PRKCA	S846	G840E	840	Missense	distal	-6	no	19.804	19.837	EPSD	COSMIC	16.704	Up-regulation
AGC_PKC_PKCa_PRKCA_ST	Q13002	GRIK2	P17252	PRKCA	S846	S846F	846	Missense	central	0	yes	19.804	0.000	EPSD	COSMIC	16.704	Loss
AGC_PKC_PKCa_PRKCA_ST	Q13002	GRIK2	P17252	PRKCA	S868	S868F	868	Missense	central	0	yes	22.309	0.000	PhosphoSitePlus	COSMIC	16.704	Loss
AGC_PKC_PKCa_PRKCA_ST	Q13002	GRIK2	P17252	PRKCA	S868	R873H	873	Missense	distal	5	no	22.309	22.049	PhosphoSitePlus	COSMIC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	Q13002	GRIK2	P17252	PRKCA	S868	R874W	874	Missense	distal	6	no	22.309	22.061	PhosphoSitePlus	COSMIC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	Q13002	GRIK2	P17252	PRKCA	S868	E863G	863	Missense	distal	-5	no	22.309	22.325	PhosphoSitePlus	COSMIC	16.704	Up-regulation
AGC_PKC_PKCa_PRKCA_ST	Q13002	GRIK2	P17252	PRKCA	S868	R874Q	874	Missense	distal	6	no	22.309	22.186	PhosphoSitePlus	COSMIC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	Q13002	GRIK2	P17252	PRKCA	S868	E864A	864	Missense	distal	-4	no	22.309	22.898	PhosphoSitePlus	COSMIC	16.704	Up-regulation
AGC_PKC_PKCa_PRKCA_ST	P45379	TNNT2	P17252	PRKCA	T204	K200R	200	Missense	distal	-4	no	19.034	18.999	EPSD	COSMIC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	P45379	TNNT2	P17252	PRKCA	T204	Q203K	203	Missense	proximal	-1	no	19.034	19.909	EPSD	COSMIC	16.704	Up-regulation
AGC_PKC_PKCa_PRKCA_ST	P45379	TNNT2	P17252	PRKCA	T204	R206W	206	Missense	proximal	2	no	19.034	13.594	EPSD	COSMIC	16.704	Loss
AGC_PKC_PKCa_PRKCA_ST	P45379	TNNT2	P17252	PRKCA	T204	A202D	202	Missense	proximal	-2	no	19.034	18.701	EPSD	COSMIC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	P45379	TNNT2	P17252	PRKCA	T204	K207R	207	Missense	distal	3	no	19.034	19.656	EPSD	COSMIC	16.704	Up-regulation
AGC_PKC_PKCa_PRKCA_ST	P45379	TNNT2	P17252	PRKCA	T204	Q199L	199	Missense	distal	-5	no	19.034	19.058	EPSD	COSMIC	16.704	Up-regulation
AGC_PKC_PKCa_PRKCA_ST	P45379	TNNT2	P17252	PRKCA	T204	K210E	210	Missense	distal	6	no	19.034	18.940	EPSD	COSMIC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	P45379	TNNT2	P17252	PRKCA	T204	E205D	205	Missense	proximal	1	no	19.034	19.001	EPSD	COSMIC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	P45379	TNNT2	P17252	PRKCA	S208	T213S	213	Missense	distal	5	no	21.569	21.744	EPSD	COSMIC	16.704	Up-regulation
AGC_PKC_PKCa_PRKCA_ST	P45379	TNNT2	P17252	PRKCA	S208	Q203K	203	Missense	distal	-5	no	21.569	21.708	EPSD	COSMIC	16.704	Up-regulation
AGC_PKC_PKCa_PRKCA_ST	P45379	TNNT2	P17252	PRKCA	S208	R215W	215	Missense	distal	7	no	21.569	21.388	EPSD	COSMIC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	P45379	TNNT2	P17252	PRKCA	S208	R206W	206	Missense	proximal	-2	no	21.569	19.571	EPSD	COSMIC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	P45379	TNNT2	P17252	PRKCA	S208	A202D	202	Missense	distal	-6	no	21.569	21.521	EPSD	COSMIC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	P45379	TNNT2	P17252	PRKCA	S208	K207R	207	Missense	proximal	-1	no	21.569	21.512	EPSD	COSMIC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	P45379	TNNT2	P17252	PRKCA	S208	K210E	210	Missense	proximal	2	no	21.569	16.289	EPSD	COSMIC	16.704	Loss
AGC_PKC_PKCa_PRKCA_ST	P45379	TNNT2	P17252	PRKCA	S208	E205D	205	Missense	distal	-3	no	21.569	21.465	EPSD	COSMIC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	P45379	TNNT2	P17252	PRKCA	T213	K220R	220	Missense	distal	7	no	21.541	21.490	EPSD	COSMIC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	P45379	TNNT2	P17252	PRKCA	T213	K220E	220	Missense	distal	7	no	21.541	21.395	EPSD	COSMIC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	P45379	TNNT2	P17252	PRKCA	T213	E216K	216	Missense	distal	3	no	21.541	22.157	EPSD	COSMIC	16.704	Up-regulation
AGC_PKC_PKCa_PRKCA_ST	P45379	TNNT2	P17252	PRKCA	T213	R215W	215	Missense	proximal	2	no	21.541	16.101	EPSD	COSMIC	16.704	Loss
AGC_PKC_PKCa_PRKCA_ST	P45379	TNNT2	P17252	PRKCA	T213	R206W	206	Missense	distal	-7	no	21.541	21.524	EPSD	COSMIC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	P45379	TNNT2	P17252	PRKCA	T213	K207R	207	Missense	distal	-6	no	21.541	21.548	EPSD	COSMIC	16.704	Up-regulation
AGC_PKC_PKCa_PRKCA_ST	P45379	TNNT2	P17252	PRKCA	T213	K210E	210	Missense	distal	-3	no	21.541	18.629	EPSD	COSMIC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	P45379	TNNT2	P17252	PRKCA	S249	L246R	246	Missense	distal	-3	no	13.425	17.781	EPSD	COSMIC	16.704	Gain
AGC_PKC_PKCa_PRKCA_ST	Q96C90	PPP1R14B	P17252	PRKCA	S21	G18R	18	Missense	distal	-3	no	14.752	18.013	EPSD	COSMIC	16.704	Gain
AGC_PKC_PKCa_PRKCA_ST	Q09472	EP300	P17252	PRKCA	S12	E7K	7	Missense	distal	-5	no	22.214	22.508	EPSD	COSMIC	16.704	Up-regulation
AGC_PKC_PKCa_PRKCA_ST	Q09472	EP300	P17252	PRKCA	S12	P10R	10	Missense	proximal	-2	no	22.214	25.256	EPSD	COSMIC	16.704	Up-regulation
AGC_PKC_PKCa_PRKCA_ST	Q09472	EP300	P17252	PRKCA	S12	G9R	9	Missense	distal	-3	no	22.214	25.476	EPSD	COSMIC	16.704	Up-regulation
AGC_PKC_PKCa_PRKCA_ST	Q09472	EP300	P17252	PRKCA	S12	A13T	13	Missense	proximal	1	no	22.214	21.743	EPSD	COSMIC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	Q09472	EP300	P17252	PRKCA	S12	A13V	13	Missense	proximal	1	no	22.214	22.368	EPSD	COSMIC	16.704	Up-regulation
AGC_PKC_PKCa_PRKCA_ST	Q09472	EP300	P17252	PRKCA	S12	V5L	5	Missense	distal	-7	no	22.214	22.217	EPSD	COSMIC;CCLE	16.704	Up-regulation
AGC_PKC_PKCa_PRKCA_ST	Q09472	EP300	P17252	PRKCA	S12	S12A	12	Missense	central	0	yes	22.214	0.000	EPSD	COSMIC	16.704	Loss
AGC_PKC_PKCa_PRKCA_ST	Q09472	EP300	P17252	PRKCA	S20	A13T	13	Missense	distal	-7	no	16.832	16.827	EPSD	COSMIC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	Q09472	EP300	P17252	PRKCA	S20	P21L	21	Missense	proximal	1	no	16.832	17.258	EPSD	COSMIC	16.704	Up-regulation
AGC_PKC_PKCa_PRKCA_ST	Q09472	EP300	P17252	PRKCA	S20	A13V	13	Missense	distal	-7	no	16.832	16.821	EPSD	COSMIC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	Q09472	EP300	P17252	PRKCA	S384	T380A	380	Missense	distal	-4	no	16.999	17.748	EPSD	COSMIC	16.704	Up-regulation
AGC_PKC_PKCa_PRKCA_ST	Q09472	EP300	P17252	PRKCA	S384	T380I	380	Missense	distal	-4	no	16.999	17.219	EPSD	COSMIC	16.704	Up-regulation
AGC_PKC_PKCa_PRKCA_ST	Q09472	EP300	P17252	PRKCA	S384	C382Y	382	Missense	proximal	-2	no	16.999	15.971	EPSD	COSMIC	16.704	Loss
AGC_PKC_PKCa_PRKCA_ST	Q09472	EP300	P17252	PRKCA	S395	R397Q	397	Missense	proximal	2	no	16.913	13.079	EPSD	COSMIC	16.704	Loss
AGC_PKC_PKCa_PRKCA_ST	Q09472	EP300	P17252	PRKCA	S395	I400F	400	Missense	distal	5	no	16.913	17.141	EPSD	COSMIC	16.704	Up-regulation
AGC_PKC_PKCa_PRKCA_ST	Q09472	EP300	P17252	PRKCA	S395	I400S	400	Missense	distal	5	no	16.913	17.107	EPSD	COSMIC	16.704	Up-regulation
AGC_PKC_PKCa_PRKCA_ST	Q09472	EP300	P17252	PRKCA	S395	C393S	393	Missense	proximal	-2	no	16.913	15.312	EPSD	COSMIC	16.704	Loss
AGC_PKC_PKCa_PRKCA_ST	Q09472	EP300	P17252	PRKCA	S395	A394S	394	Missense	proximal	-1	no	16.913	17.473	EPSD	COSMIC	16.704	Up-regulation
AGC_PKC_PKCa_PRKCA_ST	Q09472	EP300	P17252	PRKCA	S395	R397P	397	Missense	proximal	2	no	16.913	11.711	EPSD	COSMIC	16.704	Loss
AGC_PKC_PKCa_PRKCA_ST	Q09472	EP300	P17252	PRKCA	T885	P882R	882	Missense	distal	-3	no	13.852	17.700	EPSD	COSMIC	16.704	Gain
AGC_PKC_PKCa_PRKCA_ST	Q09472	EP300	P17252	PRKCA	S1009	E1011K	1011	Missense	proximal	2	no	13.070	18.349	EPSD	COSMIC	16.704	Gain
AGC_PKC_PKCa_PRKCA_ST	Q09472	EP300	P17252	PRKCA	S1044	S1037L	1037	Missense	distal	-7	no	17.120	17.115	EPSD	COSMIC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	Q09472	EP300	P17252	PRKCA	S1044	G1042R	1042	Missense	proximal	-2	no	17.120	19.992	EPSD	COSMIC	16.704	Up-regulation
AGC_PKC_PKCa_PRKCA_ST	Q09472	EP300	P17252	PRKCA	S1044	P1051L	1051	Missense	distal	7	no	17.120	17.087	EPSD	COSMIC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	Q09472	EP300	P17252	PRKCA	T1135	S1136P	1136	Missense	proximal	1	no	18.975	19.374	EPSD	COSMIC	16.704	Up-regulation
AGC_PKC_PKCa_PRKCA_ST	Q09472	EP300	P17252	PRKCA	T1135	C1142F	1142	Missense	distal	7	no	18.975	19.088	EPSD	COSMIC	16.704	Up-regulation
AGC_PKC_PKCa_PRKCA_ST	Q09472	EP300	P17252	PRKCA	T1135	R1137L	1137	Missense	proximal	2	no	18.975	13.988	EPSD	COSMIC	16.704	Loss
AGC_PKC_PKCa_PRKCA_ST	Q09472	EP300	P17252	PRKCA	T1135	Y1141N	1141	Missense	distal	6	no	18.975	18.853	EPSD	COSMIC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	Q09472	EP300	P17252	PRKCA	S1193	D1188N	1188	Missense	distal	-5	no	17.037	17.067	EPSD	COSMIC	16.704	Up-regulation
AGC_PKC_PKCa_PRKCA_ST	Q09472	EP300	P17252	PRKCA	S1193	R1197W	1197	Missense	distal	4	no	17.037	15.501	EPSD	COSMIC	16.704	Loss
AGC_PKC_PKCa_PRKCA_ST	Q09472	EP300	P17252	PRKCA	S1193	Q1195H	1195	Missense	proximal	2	no	17.037	15.848	EPSD	COSMIC	16.704	Loss
AGC_PKC_PKCa_PRKCA_ST	Q09472	EP300	P17252	PRKCA	S1295	T1300I	1300	Missense	distal	5	no	21.387	21.369	EPSD	COSMIC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	Q09472	EP300	P17252	PRKCA	S1295	L1298R	1298	Missense	distal	3	no	21.387	23.625	EPSD	COSMIC	16.704	Up-regulation
AGC_PKC_PKCa_PRKCA_ST	Q09472	EP300	P17252	PRKCA	T1296	L1298R	1298	Missense	proximal	2	no	12.125	17.112	EPSD	COSMIC	16.704	Gain
AGC_PKC_PKCa_PRKCA_ST	Q09472	EP300	P17252	PRKCA	S1581	L1584R	1584	Missense	distal	3	no	16.285	18.523	EPSD	COSMIC;CCLE	16.704	Gain
AGC_PKC_PKCa_PRKCA_ST	Q09472	EP300	P17252	PRKCA	S1730	S1730Y	1730	Missense	central	0	yes	18.150	0.000	EPSD	COSMIC	16.704	Loss
AGC_PKC_PKCa_PRKCA_ST	Q09472	EP300	P17252	PRKCA	S1730	S1730F	1730	Missense	central	0	yes	18.150	0.000	EPSD	COSMIC	16.704	Loss
AGC_PKC_PKCa_PRKCA_ST	Q09472	EP300	P17252	PRKCA	S1730	R1732H	1732	Missense	proximal	2	no	18.150	13.126	EPSD	COSMIC	16.704	Loss
AGC_PKC_PKCa_PRKCA_ST	Q09472	EP300	P17252	PRKCA	S1734	S1730Y	1730	Missense	distal	-4	no	21.175	20.981	EPSD	COSMIC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	Q09472	EP300	P17252	PRKCA	S1734	S1730F	1730	Missense	distal	-4	no	21.175	21.117	EPSD	COSMIC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	Q09472	EP300	P17252	PRKCA	S1734	R1732H	1732	Missense	proximal	-2	no	21.175	16.621	EPSD	COSMIC	16.704	Loss
AGC_PKC_PKCa_PRKCA_ST	Q09472	EP300	P17252	PRKCA	S1834	G1839D	1839	Missense	distal	5	no	20.807	20.727	EPSD	COSMIC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	Q09472	EP300	P17252	PRKCA	S1834	T1838N	1838	Missense	distal	4	no	20.807	20.528	EPSD	COSMIC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	Q09472	EP300	P17252	PRKCA	S1834	G1839S	1839	Missense	distal	5	no	20.807	20.947	EPSD	COSMIC	16.704	Up-regulation
AGC_PKC_PKCa_PRKCA_ST	Q09472	EP300	P17252	PRKCA	S1834	R1837W	1837	Missense	distal	3	no	20.807	17.873	EPSD	COSMIC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	Q09472	EP300	P17252	PRKCA	S2315	P2314T	2314	Missense	proximal	-1	no	16.834	16.755	EPSD	COSMIC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	Q09472	EP300	P17252	PRKCA	S2315	R2317W	2317	Missense	proximal	2	no	16.834	11.394	EPSD	COSMIC	16.704	Loss
AGC_PKC_PKCa_PRKCA_ST	Q09472	EP300	P17252	PRKCA	S2315	P2312S	2312	Missense	distal	-3	no	16.834	17.812	EPSD	COSMIC	16.704	Up-regulation
AGC_PKC_PKCa_PRKCA_ST	Q09472	EP300	P17252	PRKCA	S2320	H2324T	2324	Missense	distal	4	no	17.549	17.154	EPSD	COSMIC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	Q09472	EP300	P17252	PRKCA	S2320	P2314T	2314	Missense	distal	-6	no	17.549	17.455	EPSD	COSMIC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	Q09472	EP300	P17252	PRKCA	S2320	R2317W	2317	Missense	distal	-3	no	17.549	15.195	EPSD	COSMIC	16.704	Loss
AGC_PKC_PKCa_PRKCA_ST	Q09472	EP300	P17252	PRKCA	S2320	H2324Y	2324	Missense	distal	4	no	17.549	17.188	EPSD	COSMIC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	Q09472	EP300	P17252	PRKCA	S2328	H2324T	2324	Missense	distal	-4	no	19.642	19.361	EPSD	COSMIC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	Q09472	EP300	P17252	PRKCA	S2328	H2324Y	2324	Missense	distal	-4	no	19.642	19.829	EPSD	COSMIC	16.704	Up-regulation
AGC_PKC_PKCa_PRKCA_ST	O14920	IKBKB	P17252	PRKCA	S372	G374R	374	Missense	proximal	2	no	11.779	17.024	EPSD	COSMIC	16.704	Gain
AGC_PKC_PKCa_PRKCA_ST	O14920	IKBKB	P17252	PRKCA	S402	R404Q	404	Missense	proximal	2	no	18.581	14.747	EPSD	COSMIC;CCLE	16.704	Loss
AGC_PKC_PKCa_PRKCA_ST	O14920	IKBKB	P17252	PRKCA	S402	S402F	402	Missense	central	0	yes	18.581	0.000	EPSD	COSMIC	16.704	Loss
AGC_PKC_PKCa_PRKCA_ST	O14920	IKBKB	P17252	PRKCA	S402	R404L	404	Missense	proximal	2	no	18.581	13.595	EPSD	COSMIC	16.704	Loss
AGC_PKC_PKCa_PRKCA_ST	O14920	IKBKB	P17252	PRKCA	S489	D493N	493	Missense	distal	4	no	17.149	16.791	EPSD	COSMIC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	O14920	IKBKB	P17252	PRKCA	S489	Q491H	491	Missense	proximal	2	no	17.149	15.959	EPSD	COSMIC	16.704	Loss
AGC_PKC_PKCa_PRKCA_ST	O14920	IKBKB	P17252	PRKCA	S489	D484Y	484	Missense	distal	-5	no	17.149	17.025	EPSD	COSMIC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	O14920	IKBKB	P17252	PRKCA	S682	N677D	677	Missense	distal	-5	no	18.847	18.818	EPSD	COSMIC;GDSC;CCLE	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	O14920	IKBKB	P17252	PRKCA	S682	Q683K	683	Missense	proximal	1	no	18.847	19.001	EPSD	COSMIC	16.704	Up-regulation
AGC_PKC_PKCa_PRKCA_ST	O14920	IKBKB	P17252	PRKCA	S682	S679F	679	Missense	distal	-3	no	18.847	19.096	EPSD	COSMIC	16.704	Up-regulation
AGC_PKC_PKCa_PRKCA_ST	O14920	IKBKB	P17252	PRKCA	S682	R680P	680	Missense	proximal	-2	no	18.847	15.805	EPSD	COSMIC	16.704	Loss
AGC_PKC_PKCa_PRKCA_ST	O14920	IKBKB	P17252	PRKCA	S682	A678V	678	Missense	distal	-4	no	18.847	18.288	EPSD	COSMIC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	O14920	IKBKB	P17252	PRKCA	S682	S689F	689	Missense	distal	7	no	18.847	18.784	EPSD	COSMIC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	O14920	IKBKB	P17252	PRKCA	S689	T693M	693	Missense	distal	4	no	16.311	16.793	EPSD	COSMIC;CCLE	16.704	Gain
AGC_PKC_PKCa_PRKCA_ST	O14920	IKBKB	P17252	PRKCA	S689	T693A	693	Missense	distal	4	no	16.311	16.759	EPSD	COSMIC	16.704	Gain
AGC_PKC_PKCa_PRKCA_ST	O14920	IKBKB	P17252	PRKCA	S692	T693M	693	Missense	proximal	1	no	17.166	17.451	EPSD	COSMIC;CCLE	16.704	Up-regulation
AGC_PKC_PKCa_PRKCA_ST	O14920	IKBKB	P17252	PRKCA	S692	A694V	694	Missense	proximal	2	no	17.166	16.851	EPSD	COSMIC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	O14920	IKBKB	P17252	PRKCA	S692	T693A	693	Missense	proximal	1	no	17.166	17.638	EPSD	COSMIC	16.704	Up-regulation
AGC_PKC_PKCa_PRKCA_ST	O14920	IKBKB	P17252	PRKCA	S692	S689F	689	Missense	distal	-3	no	17.166	17.416	EPSD	COSMIC	16.704	Up-regulation
AGC_PKC_PKCa_PRKCA_ST	Q8N0W4	NLGN4X	P17252	PRKCA	T249	G256V	256	Missense	distal	7	no	17.149	17.071	EPSD	COSMIC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	Q8N0W4	NLGN4X	P17252	PRKCA	T249	P245L	245	Missense	distal	-4	no	17.149	16.890	EPSD	COSMIC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	Q8N0W4	NLGN4X	P17252	PRKCA	T249	A255V	255	Missense	distal	6	no	17.149	17.031	EPSD	COSMIC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	Q8N0W4	NLGN4X	P17252	PRKCA	T249	R247T	247	Missense	proximal	-2	no	17.149	14.256	EPSD	COSMIC	16.704	Loss
AGC_PKC_PKCa_PRKCA_ST	Q8N0W4	NLGN4X	P17252	PRKCA	T249	D244F	244	Missense	distal	-5	no	17.149	17.211	EPSD	COSMIC	16.704	Up-regulation
AGC_PKC_PKCa_PRKCA_ST	Q8N0W4	NLGN4X	P17252	PRKCA	T635	P634S	634	Missense	proximal	-1	no	16.557	16.857	EPSD	COSMIC	16.704	Gain
AGC_PKC_PKCa_PRKCA_ST	Q8N0W4	NLGN4X	P17252	PRKCA	T636	A640V	640	Missense	distal	4	no	17.602	16.264	EPSD	COSMIC	16.704	Loss
AGC_PKC_PKCa_PRKCA_ST	Q8N0W4	NLGN4X	P17252	PRKCA	T636	P634S	634	Missense	proximal	-2	no	17.602	17.342	EPSD	COSMIC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	Q8N0W4	NLGN4X	P17252	PRKCA	T707	P713L	713	Missense	distal	6	no	21.286	21.242	PhosphoSitePlus	COSMIC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	Q8N0W4	NLGN4X	P17252	PRKCA	T707	P713R	713	Missense	distal	6	no	21.286	21.324	PhosphoSitePlus	COSMIC	16.704	Up-regulation
AGC_PKC_PKCa_PRKCA_ST	Q8N0W4	NLGN4X	P17252	PRKCA	T707	K702T	702	Missense	distal	-5	no	21.286	21.200	PhosphoSitePlus	COSMIC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	Q8N0W4	NLGN4X	P17252	PRKCA	T707	Q714K	714	Missense	distal	7	no	21.286	21.341	PhosphoSitePlus	COSMIC	16.704	Up-regulation
AGC_PKC_PKCa_PRKCA_ST	Q8N0W4	NLGN4X	P17252	PRKCA	T707	R710S	710	Missense	distal	3	no	21.286	19.895	PhosphoSitePlus	COSMIC;GDSC;CCLE	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	Q8N0W4	NLGN4X	P17252	PRKCA	S712	P713L	713	Missense	proximal	1	no	22.370	22.796	EPSD	COSMIC	16.704	Up-regulation
AGC_PKC_PKCa_PRKCA_ST	Q8N0W4	NLGN4X	P17252	PRKCA	S712	P713R	713	Missense	proximal	1	no	22.370	23.144	EPSD	COSMIC	16.704	Up-regulation
AGC_PKC_PKCa_PRKCA_ST	Q8N0W4	NLGN4X	P17252	PRKCA	S712	Q714K	714	Missense	proximal	2	no	22.370	25.782	EPSD	COSMIC	16.704	Up-regulation
AGC_PKC_PKCa_PRKCA_ST	Q8N0W4	NLGN4X	P17252	PRKCA	S712	R710S	710	Missense	proximal	-2	no	22.370	19.068	EPSD	COSMIC;GDSC;CCLE	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	P49407	ARRB1	P17252	PRKCA	S163	R161W	161	Missense	proximal	-2	no	21.728	19.730	PhosphoSitePlus	COSMIC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	P08567	PLEK	P17252	PRKCA	S16	V12L	12	Missense	distal	-4	no	18.941	18.982	EPSD	COSMIC	16.704	Up-regulation
AGC_PKC_PKCa_PRKCA_ST	P08567	PLEK	P17252	PRKCA	S113	K108I	108	Missense	distal	-5	no	22.977	22.418	PhosphoSitePlus;EPSD	COSMIC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	P08567	PLEK	P17252	PRKCA	S113	S117C	117	Missense	distal	4	no	22.977	21.822	PhosphoSitePlus;EPSD	COSMIC;CCLE	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	P08567	PLEK	P17252	PRKCA	S113	S113Y	113	Missense	central	0	yes	22.977	0.000	PhosphoSitePlus;EPSD	COSMIC	16.704	Loss
AGC_PKC_PKCa_PRKCA_ST	P08567	PLEK	P17252	PRKCA	S113	G106C	106	Missense	distal	-7	no	22.977	22.967	PhosphoSitePlus;EPSD	COSMIC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	P08567	PLEK	P17252	PRKCA	T114	P121T	121	Missense	distal	7	no	21.199	21.169	EPSD	COSMIC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	P08567	PLEK	P17252	PRKCA	T114	K108I	108	Missense	distal	-6	no	21.199	21.035	EPSD	COSMIC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	P08567	PLEK	P17252	PRKCA	T114	S117C	117	Missense	distal	3	no	21.199	19.971	EPSD	COSMIC;CCLE	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	P08567	PLEK	P17252	PRKCA	T114	S113Y	113	Missense	proximal	-1	no	21.199	20.749	EPSD	COSMIC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	P08567	PLEK	P17252	PRKCA	S117	P121T	121	Missense	distal	4	no	22.507	22.276	EPSD;PhosphoSitePlus	COSMIC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	P08567	PLEK	P17252	PRKCA	S117	S117C	117	Missense	central	0	yes	22.507	0.000	EPSD;PhosphoSitePlus	COSMIC;CCLE	16.704	Loss
AGC_PKC_PKCa_PRKCA_ST	P08567	PLEK	P17252	PRKCA	S117	S113Y	113	Missense	distal	-4	no	22.507	22.313	EPSD;PhosphoSitePlus	COSMIC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	P08567	PLEK	P17252	PRKCA	S132	S132A	132	Missense	central	0	yes	17.855	0.000	EPSD	COSMIC	16.704	Loss
AGC_PKC_PKCa_PRKCA_ST	P08567	PLEK	P17252	PRKCA	T136	S132A	132	Missense	distal	-4	no	16.674	16.761	EPSD	COSMIC	16.704	Gain
AGC_PKC_PKCa_PRKCA_ST	O60500	NPHS1	P17252	PRKCA	T305	V301L	301	Missense	distal	-4	no	19.529	19.570	EPSD	COSMIC	16.704	Up-regulation
AGC_PKC_PKCa_PRKCA_ST	O60500	NPHS1	P17252	PRKCA	T305	P308T	308	Missense	distal	3	no	19.529	19.223	EPSD	COSMIC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	O60500	NPHS1	P17252	PRKCA	S700	S701R	701	Missense	proximal	1	no	15.656	16.830	EPSD	COSMIC	16.704	Gain
AGC_PKC_PKCa_PRKCA_ST	P09693	CD3G	P17252	PRKCA	S145	A147S	147	Missense	proximal	2	no	17.931	18.010	EPSD	COSMIC	16.704	Up-regulation
AGC_PKC_PKCa_PRKCA_ST	P09693	CD3G	P17252	PRKCA	S145	S148P	148	Missense	distal	3	no	17.931	17.792	EPSD	COSMIC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	P09693	CD3G	P17252	PRKCA	S145	R143H	143	Missense	proximal	-2	no	17.931	13.378	EPSD	COSMIC	16.704	Loss
AGC_PKC_PKCa_PRKCA_ST	P09693	CD3G	P17252	PRKCA	S145	S145P	145	Missense	central	0	yes	17.931	0.000	EPSD	COSMIC;GDSC;CCLE	16.704	Loss
AGC_PKC_PKCa_PRKCA_ST	P09693	CD3G	P17252	PRKCA	S148	A147S	147	Missense	proximal	-1	no	20.548	21.107	PhosphoSitePlus	COSMIC	16.704	Up-regulation
AGC_PKC_PKCa_PRKCA_ST	P09693	CD3G	P17252	PRKCA	S148	P155L	155	Missense	distal	7	no	20.548	20.514	PhosphoSitePlus	COSMIC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	P09693	CD3G	P17252	PRKCA	S148	S148P	148	Missense	central	0	yes	20.548	0.000	PhosphoSitePlus	COSMIC	16.704	Loss
AGC_PKC_PKCa_PRKCA_ST	P09693	CD3G	P17252	PRKCA	S148	R143H	143	Missense	distal	-5	no	20.548	20.192	PhosphoSitePlus	COSMIC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	P09693	CD3G	P17252	PRKCA	S148	S145P	145	Missense	distal	-3	no	20.548	19.569	PhosphoSitePlus	COSMIC;GDSC;CCLE	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	Q16875	PFKFB3	P17252	PRKCA	S22	C27R	27	Missense	distal	5	no	16.040	16.772	EPSD	COSMIC;CCLE	16.704	Gain
AGC_PKC_PKCa_PRKCA_ST	Q16875	PFKFB3	P17252	PRKCA	S273	L271M	271	Missense	proximal	-2	no	17.002	17.708	EPSD	COSMIC	16.704	Up-regulation
AGC_PKC_PKCa_PRKCA_ST	Q16875	PFKFB3	P17252	PRKCA	S461	S467N	467	Missense	distal	6	no	20.088	19.985	PhosphoSitePlus	COSMIC;GDSC;CCLE	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	Q16875	PFKFB3	P17252	PRKCA	S461	S467L	467	Missense	distal	6	no	20.088	20.077	PhosphoSitePlus	COSMIC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	Q16875	PFKFB3	P17252	PRKCA	S478	E481K	481	Missense	distal	3	no	16.721	17.337	EPSD	COSMIC	16.704	Up-regulation
AGC_PKC_PKCa_PRKCA_ST	P41091	EIF2S3	P17252	PRKCA	S418	D423N	423	Missense	distal	5	no	17.865	17.864	EPSD	COSMIC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	P41091	EIF2S3	P17252	PRKCA	S444	R445Q	445	Missense	proximal	1	no	17.904	17.787	EPSD	COSMIC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	Q13418	ILK	P17252	PRKCA	T172	R176L	176	Missense	distal	4	no	19.539	18.500	EPSD	COSMIC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	Q13418	ILK	P17252	PRKCA	T172	R176W	176	Missense	distal	4	no	19.539	18.003	EPSD	COSMIC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	Q13418	ILK	P17252	PRKCA	T172	K170N	170	Missense	proximal	-2	no	19.539	17.970	EPSD	COSMIC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	Q13418	ILK	P17252	PRKCA	T181	R176L	176	Missense	distal	-5	no	17.480	17.352	PhosphoSitePlus;EPSD	COSMIC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	Q13418	ILK	P17252	PRKCA	T181	R176W	176	Missense	distal	-5	no	17.480	17.166	PhosphoSitePlus;EPSD	COSMIC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	Q13769	THOC5	P17252	PRKCA	S210	L216V	216	Missense	distal	6	no	17.406	17.328	EPSD	COSMIC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	Q13769	THOC5	P17252	PRKCA	T322	T322A	322	Missense	central	0	yes	19.085	0.000	EPSD	COSMIC	16.704	Loss
AGC_PKC_PKCa_PRKCA_ST	Q13769	THOC5	P17252	PRKCA	T322	E319V	319	Missense	distal	-3	no	19.085	20.334	EPSD	COSMIC	16.704	Up-regulation
AGC_PKC_PKCa_PRKCA_ST	Q13769	THOC5	P17252	PRKCA	T328	T322A	322	Missense	distal	-6	no	18.431	18.520	EPSD	COSMIC	16.704	Up-regulation
AGC_PKC_PKCa_PRKCA_ST	Q13769	THOC5	P17252	PRKCA	T524	V523M	523	Missense	proximal	-1	no	14.601	16.723	EPSD	COSMIC	16.704	Gain
AGC_PKC_PKCa_PRKCA_ST	Q12791	KCNMA1	P17252	PRKCA	S12	S11G	11	Missense	proximal	-1	no	16.761	17.009	EPSD	COSMIC;CCLE	16.704	Up-regulation
AGC_PKC_PKCa_PRKCA_ST	Q12791	KCNMA1	P17252	PRKCA	S22	S21N	21	Missense	proximal	-1	no	20.823	20.665	EPSD	COSMIC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	Q12791	KCNMA1	P17252	PRKCA	S22	S26R	26	Missense	distal	4	no	20.823	21.069	EPSD	COSMIC	16.704	Up-regulation
AGC_PKC_PKCa_PRKCA_ST	Q12791	KCNMA1	P17252	PRKCA	S765	K767Q	767	Missense	proximal	2	no	20.750	17.338	EPSD	COSMIC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	Q12791	KCNMA1	P17252	PRKCA	S765	S765L	765	Missense	central	0	yes	20.750	0.000	EPSD	COSMIC	16.704	Loss
AGC_PKC_PKCa_PRKCA_ST	Q12791	KCNMA1	P17252	PRKCA	S765	K767N	767	Missense	proximal	2	no	20.750	15.801	EPSD	COSMIC	16.704	Loss
AGC_PKC_PKCa_PRKCA_ST	Q12791	KCNMA1	P17252	PRKCA	S765	P761L	761	Missense	distal	-4	no	20.750	20.491	EPSD	COSMIC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	Q12791	KCNMA1	P17252	PRKCA	S765	S762L	762	Missense	distal	-3	no	20.750	19.265	EPSD	COSMIC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	Q12791	KCNMA1	P17252	PRKCA	S765	N772S	772	Missense	distal	7	no	20.750	20.774	EPSD	COSMIC	16.704	Up-regulation
AGC_PKC_PKCa_PRKCA_ST	Q12791	KCNMA1	P17252	PRKCA	S765	R771Q	771	Missense	distal	6	no	20.750	20.628	EPSD	COSMIC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	Q12791	KCNMA1	P17252	PRKCA	S778	S782A	782	Missense	distal	4	no	17.522	17.538	EPSD	COSMIC	16.704	Up-regulation
AGC_PKC_PKCa_PRKCA_ST	Q12791	KCNMA1	P17252	PRKCA	S778	N772S	772	Missense	distal	-6	no	17.522	17.579	EPSD	COSMIC	16.704	Up-regulation
AGC_PKC_PKCa_PRKCA_ST	Q12791	KCNMA1	P17252	PRKCA	S778	R771Q	771	Missense	distal	-7	no	17.522	17.513	EPSD	COSMIC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	Q12791	KCNMA1	P17252	PRKCA	S778	S782L	782	Missense	distal	4	no	17.522	16.729	EPSD	COSMIC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	Q12791	KCNMA1	P17252	PRKCA	S778	G773R	773	Missense	distal	-5	no	17.522	17.812	EPSD	COSMIC	16.704	Up-regulation
AGC_PKC_PKCa_PRKCA_ST	Q12791	KCNMA1	P17252	PRKCA	S978	D975N	975	Missense	distal	-3	no	15.916	16.732	EPSD	COSMIC	16.704	Gain
AGC_PKC_PKCa_PRKCA_ST	Q12791	KCNMA1	P17252	PRKCA	S992	R989H	989	Missense	distal	-3	no	18.087	14.231	EPSD	COSMIC;CCLE	16.704	Loss
AGC_PKC_PKCa_PRKCA_ST	Q12791	KCNMA1	P17252	PRKCA	S992	G996R	996	Missense	distal	4	no	18.087	18.691	EPSD	COSMIC	16.704	Up-regulation
AGC_PKC_PKCa_PRKCA_ST	Q12791	KCNMA1	P17252	PRKCA	S992	I993M	993	Missense	proximal	1	no	18.087	17.037	EPSD	COSMIC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	Q12791	KCNMA1	P17252	PRKCA	S992	R989C	989	Missense	distal	-3	no	18.087	15.348	EPSD	COSMIC	16.704	Loss
AGC_PKC_PKCa_PRKCA_ST	Q12791	KCNMA1	P17252	PRKCA	S992	G986W	986	Missense	distal	-6	no	18.087	17.910	EPSD	COSMIC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	Q12791	KCNMA1	P17252	PRKCA	S992	V997I	997	Missense	distal	5	no	18.087	18.175	EPSD	COSMIC	16.704	Up-regulation
AGC_PKC_PKCa_PRKCA_ST	Q12791	KCNMA1	P17252	PRKCA	S992	R989M	989	Missense	distal	-3	no	18.087	15.115	EPSD	COSMIC	16.704	Loss
AGC_PKC_PKCa_PRKCA_ST	Q12791	KCNMA1	P17252	PRKCA	S1188	S1193Y	1193	Missense	distal	5	no	20.411	20.438	EPSD	COSMIC	16.704	Up-regulation
AGC_PKC_PKCa_PRKCA_ST	Q12791	KCNMA1	P17252	PRKCA	S1188	S1195F	1195	Missense	distal	7	no	20.411	20.348	EPSD	COSMIC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	Q12791	KCNMA1	P17252	PRKCA	S1188	S1192F	1192	Missense	distal	4	no	20.411	20.050	EPSD	COSMIC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	Q12791	KCNMA1	P17252	PRKCA	S1188	A1182V	1182	Missense	distal	-6	no	20.411	20.335	EPSD	COSMIC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	Q12791	KCNMA1	P17252	PRKCA	S1188	A1187D	1187	Missense	proximal	-1	no	20.411	20.475	EPSD	COSMIC	16.704	Up-regulation
AGC_PKC_PKCa_PRKCA_ST	Q12791	KCNMA1	P17252	PRKCA	S1188	S1193F	1193	Missense	distal	5	no	20.411	20.446	EPSD	COSMIC	16.704	Up-regulation
AGC_PKC_PKCa_PRKCA_ST	Q12791	KCNMA1	P17252	PRKCA	S1188	S1190Y	1190	Missense	proximal	2	no	20.411	20.536	EPSD	COSMIC	16.704	Up-regulation
AGC_PKC_PKCa_PRKCA_ST	Q12791	KCNMA1	P17252	PRKCA	S1188	S1195L	1195	Missense	distal	7	no	20.411	20.414	EPSD	COSMIC	16.704	Up-regulation
AGC_PKC_PKCa_PRKCA_ST	Q12791	KCNMA1	P17252	PRKCA	S1188	Q1184K	1184	Missense	distal	-4	no	20.411	20.824	EPSD	COSMIC	16.704	Up-regulation
AGC_PKC_PKCa_PRKCA_ST	Q12791	KCNMA1	P17252	PRKCA	S1200	S1196F	1196	Missense	distal	-4	no	20.403	20.345	PhosphoSitePlus	COSMIC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	Q12791	KCNMA1	P17252	PRKCA	S1200	S1198L	1198	Missense	proximal	-2	no	20.403	21.017	PhosphoSitePlus	COSMIC	16.704	Up-regulation
AGC_PKC_PKCa_PRKCA_ST	Q12791	KCNMA1	P17252	PRKCA	S1200	S1193Y	1193	Missense	distal	-7	no	20.403	20.404	PhosphoSitePlus	COSMIC	16.704	Up-regulation
AGC_PKC_PKCa_PRKCA_ST	Q12791	KCNMA1	P17252	PRKCA	S1200	S1203N	1203	Missense	distal	3	no	20.403	20.225	PhosphoSitePlus	COSMIC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	Q12791	KCNMA1	P17252	PRKCA	S1200	S1195F	1195	Missense	distal	-5	no	20.403	20.506	PhosphoSitePlus	COSMIC	16.704	Up-regulation
AGC_PKC_PKCa_PRKCA_ST	Q12791	KCNMA1	P17252	PRKCA	S1200	S1198P	1198	Missense	proximal	-2	no	20.403	20.663	PhosphoSitePlus	COSMIC	16.704	Up-regulation
AGC_PKC_PKCa_PRKCA_ST	Q12791	KCNMA1	P17252	PRKCA	S1200	K1201N	1201	Missense	proximal	1	no	20.403	19.239	PhosphoSitePlus	COSMIC;CCLE	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	Q12791	KCNMA1	P17252	PRKCA	S1200	S1205P	1205	Missense	distal	5	no	20.403	20.563	PhosphoSitePlus	COSMIC	16.704	Up-regulation
AGC_PKC_PKCa_PRKCA_ST	Q12791	KCNMA1	P17252	PRKCA	S1200	S1199F	1199	Missense	proximal	-1	no	20.403	19.696	PhosphoSitePlus	COSMIC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	Q12791	KCNMA1	P17252	PRKCA	S1200	S1193F	1193	Missense	distal	-7	no	20.403	20.396	PhosphoSitePlus	COSMIC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	Q12791	KCNMA1	P17252	PRKCA	S1200	S1200F	1200	Missense	central	0	yes	20.403	0.000	PhosphoSitePlus	COSMIC	16.704	Loss
AGC_PKC_PKCa_PRKCA_ST	Q12791	KCNMA1	P17252	PRKCA	S1200	S1200N	1200	Missense	central	0	yes	20.403	0.000	PhosphoSitePlus	COSMIC	16.704	Loss
AGC_PKC_PKCa_PRKCA_ST	Q12791	KCNMA1	P17252	PRKCA	S1200	S1203I	1203	Missense	distal	3	no	20.403	19.245	PhosphoSitePlus	COSMIC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	Q12791	KCNMA1	P17252	PRKCA	S1200	S1195L	1195	Missense	distal	-5	no	20.403	20.702	PhosphoSitePlus	COSMIC	16.704	Up-regulation
AGC_PKC_PKCa_PRKCA_ST	Q12791	KCNMA1	P17252	PRKCA	S1200	S1203F	1203	Missense	distal	3	no	20.403	19.891	PhosphoSitePlus	COSMIC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	Q12791	KCNMA1	P17252	PRKCA	S1200	S1204N	1204	Missense	distal	4	no	20.403	19.693	PhosphoSitePlus	COSMIC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	Q12791	KCNMA1	P17252	PRKCA	S1200	S1199L	1199	Missense	proximal	-1	no	20.403	19.984	PhosphoSitePlus	COSMIC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	P43119	PTGIR	P17252	PRKCA	S39	P43T	43	Missense	distal	4	no	20.602	20.371	EPSD	COSMIC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	P43119	PTGIR	P17252	PRKCA	S39	G32R	32	Missense	distal	-7	no	20.602	20.611	EPSD	COSMIC	16.704	Up-regulation
AGC_PKC_PKCa_PRKCA_ST	P43119	PTGIR	P17252	PRKCA	S39	P46S	46	Missense	distal	7	no	20.602	20.566	EPSD	COSMIC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	P43119	PTGIR	P17252	PRKCA	S328	L323F	323	Missense	distal	-5	no	21.703	21.507	PhosphoSitePlus	COSMIC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	P43119	PTGIR	P17252	PRKCA	S328	Q325L	325	Missense	distal	-3	no	21.703	20.205	PhosphoSitePlus	COSMIC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	P43119	PTGIR	P17252	PRKCA	S328	A327V	327	Missense	proximal	-1	no	21.703	20.800	PhosphoSitePlus	COSMIC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	P43119	PTGIR	P17252	PRKCA	S328	A327S	327	Missense	proximal	-1	no	21.703	22.263	PhosphoSitePlus	COSMIC	16.704	Up-regulation
AGC_PKC_PKCa_PRKCA_ST	P43119	PTGIR	P17252	PRKCA	S337	P339S	339	Missense	proximal	2	no	16.140	16.723	EPSD	COSMIC	16.704	Gain
AGC_PKC_PKCa_PRKCA_ST	P43119	PTGIR	P17252	PRKCA	S374	T373M	373	Missense	proximal	-1	no	16.225	17.263	EPSD	COSMIC	16.704	Gain
AGC_PKC_PKCa_PRKCA_ST	P09211	GSTP1	P17252	PRKCA	S28	S28R	28	Missense	central	0	yes	18.535	0.000	EPSD	COSMIC	16.704	Loss
AGC_PKC_PKCa_PRKCA_ST	P09211	GSTP1	P17252	PRKCA	S185	G182R	182	Missense	distal	-3	no	19.779	23.041	PhosphoSitePlus	COSMIC	16.704	Up-regulation
AGC_PKC_PKCa_PRKCA_ST	P09211	GSTP1	P17252	PRKCA	S185	S185R	185	Missense	central	0	yes	19.779	0.000	PhosphoSitePlus	COSMIC	16.704	Loss
AGC_PKC_PKCa_PRKCA_ST	P09211	GSTP1	P17252	PRKCA	S185	P188L	188	Missense	distal	3	no	19.779	19.072	PhosphoSitePlus	COSMIC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	Q01970	PLCB3	P17252	PRKCA	S26	E33K	33	Missense	distal	7	no	21.962	22.108	EPSD	COSMIC	16.704	Up-regulation
AGC_PKC_PKCa_PRKCA_ST	Q01970	PLCB3	P17252	PRKCA	S26	V19M	19	Missense	distal	-7	no	21.962	21.972	EPSD	COSMIC;CCLE	16.704	Up-regulation
AGC_PKC_PKCa_PRKCA_ST	Q01970	PLCB3	P17252	PRKCA	S474	H471D	471	Missense	distal	-3	no	17.287	16.102	EPSD	COSMIC	16.704	Loss
AGC_PKC_PKCa_PRKCA_ST	Q01970	PLCB3	P17252	PRKCA	S474	A481V	481	Missense	distal	7	no	17.287	17.233	EPSD	COSMIC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	Q01970	PLCB3	P17252	PRKCA	S793	S793L	793	Missense	central	0	yes	18.275	0.000	EPSD	COSMIC	16.704	Loss
AGC_PKC_PKCa_PRKCA_ST	Q01970	PLCB3	P17252	PRKCA	S793	R795H	795	Missense	proximal	2	no	18.275	13.252	EPSD	COSMIC;CCLE	16.704	Loss
AGC_PKC_PKCa_PRKCA_ST	Q01970	PLCB3	P17252	PRKCA	S916	P920H	920	Missense	distal	4	no	17.963	18.127	EPSD	COSMIC	16.704	Up-regulation
AGC_PKC_PKCa_PRKCA_ST	Q01970	PLCB3	P17252	PRKCA	S916	R918P	918	Missense	proximal	2	no	17.963	12.760	EPSD	COSMIC	16.704	Loss
AGC_PKC_PKCa_PRKCA_ST	Q01970	PLCB3	P17252	PRKCA	S916	P917S	917	Missense	proximal	1	no	17.963	17.564	EPSD	COSMIC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	Q01995	TAGLN	P17252	PRKCA	S7	A2V	2	Missense	distal	-5	no	18.512	18.428	EPSD	COSMIC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	Q01995	TAGLN	P17252	PRKCA	S7	P6S	6	Missense	proximal	-1	no	18.512	18.812	EPSD	COSMIC	16.704	Up-regulation
AGC_PKC_PKCa_PRKCA_ST	Q01995	TAGLN	P17252	PRKCA	S181	V174D	174	Missense	distal	-7	no	18.986	18.990	PhosphoSitePlus	COSMIC	16.704	Up-regulation
AGC_PKC_PKCa_PRKCA_ST	Q01995	TAGLN	P17252	PRKCA	S181	V174I	174	Missense	distal	-7	no	18.986	18.985	PhosphoSitePlus	COSMIC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	O94759	TRPM2	P17252	PRKCA	S38	S39I	39	Missense	proximal	1	no	15.672	17.334	EPSD	COSMIC	16.704	Gain
AGC_PKC_PKCa_PRKCA_ST	O94759	TRPM2	P17252	PRKCA	S603	R605L	605	Missense	proximal	2	no	16.880	11.893	EPSD	COSMIC	16.704	Loss
AGC_PKC_PKCa_PRKCA_ST	O94759	TRPM2	P17252	PRKCA	S603	R610P	610	Missense	distal	7	no	16.880	16.870	EPSD	COSMIC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	O94759	TRPM2	P17252	PRKCA	S603	R605W	605	Missense	proximal	2	no	16.880	11.440	EPSD	COSMIC	16.704	Loss
AGC_PKC_PKCa_PRKCA_ST	O94759	TRPM2	P17252	PRKCA	S612	T616I	616	Missense	distal	4	no	17.161	16.147	EPSD	COSMIC	16.704	Loss
AGC_PKC_PKCa_PRKCA_ST	O94759	TRPM2	P17252	PRKCA	S612	R605L	605	Missense	distal	-7	no	17.161	17.150	EPSD	COSMIC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	O94759	TRPM2	P17252	PRKCA	S612	R610P	610	Missense	proximal	-2	no	17.161	14.118	EPSD	COSMIC	16.704	Loss
AGC_PKC_PKCa_PRKCA_ST	O94759	TRPM2	P17252	PRKCA	S612	R605W	605	Missense	distal	-7	no	17.161	17.144	EPSD	COSMIC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	O94759	TRPM2	P17252	PRKCA	S772	E775K	775	Missense	distal	3	no	18.648	19.264	EPSD	COSMIC	16.704	Up-regulation
AGC_PKC_PKCa_PRKCA_ST	O94759	TRPM2	P17252	PRKCA	S1172	S1170L	1170	Missense	proximal	-2	no	16.832	17.446	EPSD	COSMIC	16.704	Up-regulation
AGC_PKC_PKCa_PRKCA_ST	O94759	TRPM2	P17252	PRKCA	S1172	R1176W	1176	Missense	distal	4	no	16.832	15.296	EPSD	COSMIC	16.704	Loss
AGC_PKC_PKCa_PRKCA_ST	O94901	SUN1	P17252	PRKCA	S48	R50Q	50	Missense	proximal	2	no	17.195	13.361	EPSD	COSMIC	16.704	Loss
AGC_PKC_PKCa_PRKCA_ST	O94901	SUN1	P17252	PRKCA	S52	R50Q	50	Missense	proximal	-2	no	22.535	20.776	EPSD	COSMIC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	O94901	SUN1	P17252	PRKCA	S55	R50Q	50	Missense	distal	-5	no	23.780	23.628	PhosphoSitePlus	COSMIC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	O94901	SUN1	P17252	PRKCA	S82	A80T	80	Missense	proximal	-2	no	16.743	16.935	EPSD	COSMIC	16.704	Up-regulation
AGC_PKC_PKCa_PRKCA_ST	O94901	SUN1	P17252	PRKCA	S82	S82F	82	Missense	central	0	yes	16.743	0.000	EPSD	COSMIC	16.704	Loss
AGC_PKC_PKCa_PRKCA_ST	O94901	SUN1	P17252	PRKCA	S82	A80S	80	Missense	proximal	-2	no	16.743	16.527	EPSD	COSMIC	16.704	Loss
AGC_PKC_PKCa_PRKCA_ST	O94901	SUN1	P17252	PRKCA	S96	T90A	90	Missense	distal	-6	no	18.711	18.800	EPSD	COSMIC	16.704	Up-regulation
AGC_PKC_PKCa_PRKCA_ST	O94901	SUN1	P17252	PRKCA	S96	S100A	100	Missense	distal	4	no	18.711	18.728	EPSD	COSMIC	16.704	Up-regulation
AGC_PKC_PKCa_PRKCA_ST	O94901	SUN1	P17252	PRKCA	S96	A101T	101	Missense	distal	5	no	18.711	18.433	EPSD	COSMIC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	O94901	SUN1	P17252	PRKCA	S96	S103F	103	Missense	distal	7	no	18.711	18.648	EPSD	COSMIC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	O94901	SUN1	P17252	PRKCA	S96	A101S	101	Missense	distal	5	no	18.711	18.608	EPSD	COSMIC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	O94901	SUN1	P17252	PRKCA	T97	T90A	90	Missense	distal	-7	no	23.472	23.477	EPSD	COSMIC	16.704	Up-regulation
AGC_PKC_PKCa_PRKCA_ST	O94901	SUN1	P17252	PRKCA	T97	S100A	100	Missense	distal	3	no	23.472	23.266	EPSD	COSMIC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	O94901	SUN1	P17252	PRKCA	T97	A101T	101	Missense	distal	4	no	23.472	23.025	EPSD	COSMIC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	O94901	SUN1	P17252	PRKCA	T97	S103F	103	Missense	distal	6	no	23.472	23.431	EPSD	COSMIC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	O94901	SUN1	P17252	PRKCA	T97	A101S	101	Missense	distal	4	no	23.472	23.456	EPSD	COSMIC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	O94901	SUN1	P17252	PRKCA	T370	L373V	373	Missense	distal	3	no	16.458	16.842	EPSD	COSMIC	16.704	Gain
AGC_PKC_PKCa_PRKCA_ST	O94901	SUN1	P17252	PRKCA	S437	G443V	443	Missense	distal	6	no	17.033	17.022	EPSD	COSMIC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	O94901	SUN1	P17252	PRKCA	S437	D440E	440	Missense	distal	3	no	17.033	17.520	EPSD	COSMIC	16.704	Up-regulation
AGC_PKC_PKCa_PRKCA_ST	Q9C0K0	BCL11B	P17252	PRKCA	S13	I18T	18	Missense	distal	5	no	19.791	19.810	EPSD	COSMIC	16.704	Up-regulation
AGC_PKC_PKCa_PRKCA_ST	Q9C0K0	BCL11B	P17252	PRKCA	S13	L17F	17	Missense	distal	4	no	19.791	20.222	EPSD	COSMIC	16.704	Up-regulation
AGC_PKC_PKCa_PRKCA_ST	Q9C0K0	BCL11B	P17252	PRKCA	S101	S97N	97	Missense	distal	-4	no	17.717	17.387	EPSD	COSMIC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	Q9C0K0	BCL11B	P17252	PRKCA	S101	L106P	106	Missense	distal	5	no	17.717	18.067	EPSD	COSMIC	16.704	Up-regulation
AGC_PKC_PKCa_PRKCA_ST	Q9C0K0	BCL11B	P17252	PRKCA	S101	D96E	96	Missense	distal	-5	no	17.717	17.795	EPSD	COSMIC	16.704	Up-regulation
AGC_PKC_PKCa_PRKCA_ST	Q9C0K0	BCL11B	P17252	PRKCA	S101	P100S	100	Missense	proximal	-1	no	17.717	18.017	EPSD	COSMIC	16.704	Up-regulation
AGC_PKC_PKCa_PRKCA_ST	Q9C0K0	BCL11B	P17252	PRKCA	S129	H126R	126	Missense	distal	-3	no	14.010	17.866	EPSD	COSMIC	16.704	Gain
AGC_PKC_PKCa_PRKCA_ST	Q9C0K0	BCL11B	P17252	PRKCA	S331	E333K	333	Missense	proximal	2	no	14.068	19.348	EPSD	COSMIC	16.704	Gain
AGC_PKC_PKCa_PRKCA_ST	Q9C0K0	BCL11B	P17252	PRKCA	S364	A360S	360	Missense	distal	-4	no	19.032	18.945	EPSD	COSMIC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	Q9C0K0	BCL11B	P17252	PRKCA	S364	S358A	358	Missense	distal	-6	no	19.032	18.995	EPSD	COSMIC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	Q9C0K0	BCL11B	P17252	PRKCA	S364	R365Q	365	Missense	proximal	1	no	19.032	18.915	EPSD	COSMIC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	Q9C0K0	BCL11B	P17252	PRKCA	S364	R366W	366	Missense	proximal	2	no	19.032	13.592	EPSD	COSMIC	16.704	Loss
AGC_PKC_PKCa_PRKCA_ST	Q9C0K0	BCL11B	P17252	PRKCA	S398	P394H	394	Missense	distal	-4	no	18.381	18.171	EPSD	COSMIC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	Q9C0K0	BCL11B	P17252	PRKCA	S398	P402S	402	Missense	distal	4	no	18.381	18.581	EPSD	COSMIC	16.704	Up-regulation
AGC_PKC_PKCa_PRKCA_ST	Q9C0K0	BCL11B	P17252	PRKCA	S398	S398G	398	Missense	central	0	yes	18.381	0.000	EPSD	COSMIC	16.704	Loss
AGC_PKC_PKCa_PRKCA_ST	Q9C0K0	BCL11B	P17252	PRKCA	S398	P402L	402	Missense	distal	4	no	18.381	17.789	EPSD	COSMIC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	Q9C0K0	BCL11B	P17252	PRKCA	S398	S405N	405	Missense	distal	7	no	18.381	18.357	EPSD	COSMIC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	Q9C0K0	BCL11B	P17252	PRKCA	S483	G486V	486	Missense	distal	3	no	18.915	17.700	EPSD	COSMIC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	Q9C0K0	BCL11B	P17252	PRKCA	S483	G486E	486	Missense	distal	3	no	18.915	18.316	EPSD	COSMIC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	Q9C0K0	BCL11B	P17252	PRKCA	S483	R487C	487	Missense	distal	4	no	18.915	17.513	EPSD	COSMIC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	Q9C0K0	BCL11B	P17252	PRKCA	S483	K480T	480	Missense	distal	-3	no	18.915	16.778	EPSD	COSMIC;GDSC;CCLE	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	Q9C0K0	BCL11B	P17252	PRKCA	S483	H479Y	479	Missense	distal	-4	no	18.915	19.102	EPSD	COSMIC;CCLE	16.704	Up-regulation
AGC_PKC_PKCa_PRKCA_ST	Q9C0K0	BCL11B	P17252	PRKCA	S497	E499K	499	Missense	proximal	2	no	11.928	17.208	EPSD	COSMIC	16.704	Gain
AGC_PKC_PKCa_PRKCA_ST	Q9C0K0	BCL11B	P17252	PRKCA	S744	E746K	746	Missense	proximal	2	no	13.709	18.989	EPSD	COSMIC	16.704	Gain
AGC_PKC_PKCa_PRKCA_ST	Q9C0K0	BCL11B	P17252	PRKCA	S749	G748D	748	Missense	proximal	-1	no	17.502	16.759	EPSD	COSMIC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	Q9C0K0	BCL11B	P17252	PRKCA	S749	E746K	746	Missense	distal	-3	no	17.502	20.414	EPSD	COSMIC	16.704	Up-regulation
AGC_PKC_PKCa_PRKCA_ST	Q9C0K0	BCL11B	P17252	PRKCA	S749	R751W	751	Missense	proximal	2	no	17.502	12.062	EPSD	COSMIC	16.704	Loss
AGC_PKC_PKCa_PRKCA_ST	Q9C0K0	BCL11B	P17252	PRKCA	S765	A771T	771	Missense	distal	6	no	17.505	17.427	EPSD	COSMIC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	Q9C0K0	BCL11B	P17252	PRKCA	S765	G763C	763	Missense	proximal	-2	no	17.505	18.677	EPSD	COSMIC	16.704	Up-regulation
AGC_PKC_PKCa_PRKCA_ST	Q9C0K0	BCL11B	P17252	PRKCA	S765	S768C	768	Missense	distal	3	no	17.505	16.278	EPSD	COSMIC	16.704	Loss
AGC_PKC_PKCa_PRKCA_ST	Q9C0K0	BCL11B	P17252	PRKCA	S765	G762C	762	Missense	distal	-3	no	17.505	18.028	EPSD	COSMIC	16.704	Up-regulation
AGC_PKC_PKCa_PRKCA_ST	Q9C0K0	BCL11B	P17252	PRKCA	T770	S768C	768	Missense	proximal	-2	no	15.565	17.167	EPSD	COSMIC	16.704	Gain
AGC_PKC_PKCa_PRKCA_ST	Q9C0K0	BCL11B	P17252	PRKCA	S788	R794H	794	Missense	distal	6	no	21.436	21.358	EPSD	COSMIC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	Q9C0K0	BCL11B	P17252	PRKCA	S788	P784H	784	Missense	distal	-4	no	21.436	21.226	EPSD	COSMIC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	Q9C0K0	BCL11B	P17252	PRKCA	S788	K790N	790	Missense	proximal	2	no	21.436	16.487	EPSD	COSMIC	16.704	Loss
AGC_PKC_PKCa_PRKCA_ST	Q9C0K0	BCL11B	P17252	PRKCA	S788	P787S	787	Missense	proximal	-1	no	21.436	21.735	EPSD	COSMIC	16.704	Up-regulation
AGC_PKC_PKCa_PRKCA_ST	Q9C0K0	BCL11B	P17252	PRKCA	S788	P782Q	782	Missense	distal	-6	no	21.436	21.397	EPSD	COSMIC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	Q9C0K0	BCL11B	P17252	PRKCA	S789	R794H	794	Missense	distal	5	no	19.514	19.255	EPSD	COSMIC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	Q9C0K0	BCL11B	P17252	PRKCA	S789	P784H	784	Missense	distal	-5	no	19.514	19.260	EPSD	COSMIC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	Q9C0K0	BCL11B	P17252	PRKCA	S789	K790N	790	Missense	proximal	1	no	19.514	18.350	EPSD	COSMIC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	Q9C0K0	BCL11B	P17252	PRKCA	S789	P787S	787	Missense	proximal	-2	no	19.514	19.255	EPSD	COSMIC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	Q9C0K0	BCL11B	P17252	PRKCA	S817	R822W	822	Missense	distal	5	no	21.134	20.626	EPSD	COSMIC;GDSC;CCLE	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	Q9C0K0	BCL11B	P17252	PRKCA	S817	R815W	815	Missense	proximal	-2	no	21.134	19.136	EPSD	COSMIC;CCLE	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	Q9C0K0	BCL11B	P17252	PRKCA	S817	T812N	812	Missense	distal	-5	no	21.134	20.877	EPSD	COSMIC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	P50552	VASP	P17252	PRKCA	S239	G246V	246	Missense	distal	7	no	19.742	19.663	EPSD	COSMIC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	P50552	VASP	P17252	PRKCA	S255	P248A	248	Missense	distal	-7	no	19.553	19.558	EPSD	COSMIC	16.704	Up-regulation
AGC_PKC_PKCa_PRKCA_ST	P50552	VASP	P17252	PRKCA	S255	G259A	259	Missense	distal	4	no	19.553	19.927	EPSD	COSMIC	16.704	Up-regulation
AGC_PKC_PKCa_PRKCA_ST	P50552	VASP	P17252	PRKCA	T278	G281W	281	Missense	distal	3	no	17.590	15.296	EPSD	COSMIC	16.704	Loss
AGC_PKC_PKCa_PRKCA_ST	P50552	VASP	P17252	PRKCA	S305	S305C	305	Missense	central	0	yes	20.182	0.000	EPSD	COSMIC	16.704	Loss
AGC_PKC_PKCa_PRKCA_ST	P50552	VASP	P17252	PRKCA	S305	V299F	299	Missense	distal	-6	no	20.182	20.210	EPSD	COSMIC;CCLE	16.704	Up-regulation
AGC_PKC_PKCa_PRKCA_ST	P30411	BDKRB2	P17252	PRKCA	S12	E15D	15	Missense	distal	3	no	20.839	20.352	EPSD	COSMIC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	P30411	BDKRB2	P17252	PRKCA	S12	R14H	14	Missense	proximal	2	no	20.839	15.815	EPSD	COSMIC	16.704	Loss
AGC_PKC_PKCa_PRKCA_ST	P30411	BDKRB2	P17252	PRKCA	S17	E15D	15	Missense	proximal	-2	no	16.124	16.832	EPSD	COSMIC	16.704	Gain
AGC_PKC_PKCa_PRKCA_ST	Q01954	BNC1	P17252	PRKCA	S398	S397I	397	Missense	proximal	-1	no	17.878	16.595	EPSD	COSMIC	16.704	Loss
AGC_PKC_PKCa_PRKCA_ST	Q01954	BNC1	P17252	PRKCA	S398	N393K	393	Missense	distal	-5	no	17.878	18.221	EPSD	COSMIC	16.704	Up-regulation
AGC_PKC_PKCa_PRKCA_ST	Q01954	BNC1	P17252	PRKCA	S398	G391R	391	Missense	distal	-7	no	17.878	17.888	EPSD	COSMIC	16.704	Up-regulation
AGC_PKC_PKCa_PRKCA_ST	Q01954	BNC1	P17252	PRKCA	S398	R404G	404	Missense	distal	6	no	17.878	17.729	EPSD	COSMIC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	Q01954	BNC1	P17252	PRKCA	S398	R404C	404	Missense	distal	6	no	17.878	17.639	EPSD	COSMIC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	Q01954	BNC1	P17252	PRKCA	S398	N403K	403	Missense	distal	5	no	17.878	18.385	EPSD	COSMIC	16.704	Up-regulation
AGC_PKC_PKCa_PRKCA_ST	Q01954	BNC1	P17252	PRKCA	S537	A531V	531	Missense	distal	-6	no	22.040	21.964	EPSD	COSMIC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	Q01954	BNC1	P17252	PRKCA	S541	I546L	546	Missense	distal	5	no	17.890	17.893	PhosphoSitePlus	COSMIC	16.704	Up-regulation
AGC_PKC_PKCa_PRKCA_ST	Q01954	BNC1	P17252	PRKCA	S938	K935T	935	Missense	distal	-3	no	17.817	15.680	EPSD	COSMIC;GDSC;CCLE	16.704	Loss
AGC_PKC_PKCa_PRKCA_ST	Q01954	BNC1	P17252	PRKCA	T942	K935T	935	Missense	distal	-7	no	17.837	17.834	EPSD	COSMIC;GDSC;CCLE	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	Q14524	SCN5A	P17252	PRKCA	S11	R14L	14	Missense	distal	3	no	20.342	18.104	EPSD	COSMIC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	Q14524	SCN5A	P17252	PRKCA	S11	R18L	18	Missense	distal	7	no	20.342	20.298	EPSD	COSMIC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	Q14524	SCN5A	P17252	PRKCA	S12	E19K	19	Missense	distal	7	no	24.060	24.206	EPSD	COSMIC	16.704	Up-regulation
AGC_PKC_PKCa_PRKCA_ST	Q14524	SCN5A	P17252	PRKCA	S12	R14L	14	Missense	proximal	2	no	24.060	19.073	EPSD	COSMIC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	Q14524	SCN5A	P17252	PRKCA	S12	R18L	18	Missense	distal	6	no	24.060	23.978	EPSD	COSMIC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	Q14524	SCN5A	P17252	PRKCA	T17	E19K	19	Missense	proximal	2	no	18.215	23.494	EPSD	COSMIC	16.704	Up-regulation
AGC_PKC_PKCa_PRKCA_ST	Q14524	SCN5A	P17252	PRKCA	T17	R14L	14	Missense	distal	-3	no	18.215	13.859	EPSD	COSMIC	16.704	Loss
AGC_PKC_PKCa_PRKCA_ST	Q14524	SCN5A	P17252	PRKCA	T17	R18L	18	Missense	proximal	1	no	18.215	17.867	EPSD	COSMIC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	Q14524	SCN5A	P17252	PRKCA	S20	E19K	19	Missense	proximal	-1	no	16.725	17.151	EPSD	COSMIC	16.704	Up-regulation
AGC_PKC_PKCa_PRKCA_ST	Q14524	SCN5A	P17252	PRKCA	S20	R14L	14	Missense	distal	-6	no	16.725	16.587	EPSD	COSMIC	16.704	Loss
AGC_PKC_PKCa_PRKCA_ST	Q14524	SCN5A	P17252	PRKCA	S20	R18L	18	Missense	proximal	-2	no	16.725	14.037	EPSD	COSMIC	16.704	Loss
AGC_PKC_PKCa_PRKCA_ST	Q14524	SCN5A	P17252	PRKCA	S460	V456M	456	Missense	distal	-4	no	16.661	17.406	EPSD	COSMIC	16.704	Gain
AGC_PKC_PKCa_PRKCA_ST	Q14524	SCN5A	P17252	PRKCA	S476	S476G	476	Missense	central	0	yes	23.937	0.000	EPSD	COSMIC	16.704	Loss
AGC_PKC_PKCa_PRKCA_ST	Q14524	SCN5A	P17252	PRKCA	S483	S476G	476	Missense	distal	-7	no	18.998	18.994	EPSD	COSMIC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	Q14524	SCN5A	P17252	PRKCA	S499	E500Q	500	Missense	proximal	1	no	15.630	17.080	EPSD	COSMIC	16.704	Gain
AGC_PKC_PKCa_PRKCA_ST	Q14524	SCN5A	P17252	PRKCA	S519	T518N	518	Missense	proximal	-1	no	21.739	21.959	EPSD	COSMIC	16.704	Up-regulation
AGC_PKC_PKCa_PRKCA_ST	Q14524	SCN5A	P17252	PRKCA	S519	S525R	525	Missense	distal	6	no	21.739	21.810	EPSD	COSMIC	16.704	Up-regulation
AGC_PKC_PKCa_PRKCA_ST	Q14524	SCN5A	P17252	PRKCA	S519	R523C	523	Missense	distal	4	no	21.739	20.337	EPSD	COSMIC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	Q14524	SCN5A	P17252	PRKCA	S524	T518N	518	Missense	distal	-6	no	21.073	21.142	EPSD	COSMIC	16.704	Up-regulation
AGC_PKC_PKCa_PRKCA_ST	Q14524	SCN5A	P17252	PRKCA	S524	T531P	531	Missense	distal	7	no	21.073	21.103	EPSD	COSMIC	16.704	Up-regulation
AGC_PKC_PKCa_PRKCA_ST	Q14524	SCN5A	P17252	PRKCA	S524	S525R	525	Missense	proximal	1	no	21.073	22.247	EPSD	COSMIC	16.704	Up-regulation
AGC_PKC_PKCa_PRKCA_ST	Q14524	SCN5A	P17252	PRKCA	S524	R523C	523	Missense	proximal	-1	no	21.073	18.413	EPSD	COSMIC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	Q14524	SCN5A	P17252	PRKCA	S525	T518N	518	Missense	distal	-7	no	17.417	17.415	EPSD	COSMIC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	Q14524	SCN5A	P17252	PRKCA	S525	T531P	531	Missense	distal	6	no	17.417	17.499	EPSD	COSMIC	16.704	Up-regulation
AGC_PKC_PKCa_PRKCA_ST	Q14524	SCN5A	P17252	PRKCA	S525	S525R	525	Missense	central	0	yes	17.417	0.000	EPSD	COSMIC	16.704	Loss
AGC_PKC_PKCa_PRKCA_ST	Q14524	SCN5A	P17252	PRKCA	S525	R523C	523	Missense	proximal	-2	no	17.417	15.717	EPSD	COSMIC	16.704	Loss
AGC_PKC_PKCa_PRKCA_ST	Q14524	SCN5A	P17252	PRKCA	S528	T531P	531	Missense	distal	3	no	19.052	19.358	EPSD	COSMIC	16.704	Up-regulation
AGC_PKC_PKCa_PRKCA_ST	Q14524	SCN5A	P17252	PRKCA	S528	S525R	525	Missense	distal	-3	no	19.052	21.922	EPSD	COSMIC	16.704	Up-regulation
AGC_PKC_PKCa_PRKCA_ST	Q14524	SCN5A	P17252	PRKCA	S528	R523C	523	Missense	distal	-5	no	19.052	18.377	EPSD	COSMIC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	Q14524	SCN5A	P17252	PRKCA	T531	T531P	531	Missense	central	0	yes	20.137	0.000	EPSD	COSMIC	16.704	Loss
AGC_PKC_PKCa_PRKCA_ST	Q14524	SCN5A	P17252	PRKCA	T531	G538S	538	Missense	distal	7	no	20.137	20.115	EPSD	COSMIC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	Q14524	SCN5A	P17252	PRKCA	T531	S525R	525	Missense	distal	-6	no	20.137	20.210	EPSD	COSMIC	16.704	Up-regulation
AGC_PKC_PKCa_PRKCA_ST	Q14524	SCN5A	P17252	PRKCA	S571	P576S	576	Missense	distal	5	no	22.789	22.629	EPSD	COSMIC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	Q14524	SCN5A	P17252	PRKCA	S571	W565R	565	Missense	distal	-6	no	22.789	23.073	EPSD	COSMIC;GDSC;CCLE	16.704	Up-regulation
AGC_PKC_PKCa_PRKCA_ST	Q14524	SCN5A	P17252	PRKCA	S571	R569Q	569	Missense	proximal	-2	no	22.789	21.030	EPSD	COSMIC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	Q14524	SCN5A	P17252	PRKCA	S577	G579R	579	Missense	proximal	2	no	15.759	21.005	EPSD	COSMIC	16.704	Gain
AGC_PKC_PKCa_PRKCA_ST	Q14524	SCN5A	P17252	PRKCA	S581	P576S	576	Missense	distal	-5	no	16.895	16.570	EPSD	COSMIC	16.704	Loss
AGC_PKC_PKCa_PRKCA_ST	Q14524	SCN5A	P17252	PRKCA	S581	G579E	579	Missense	proximal	-2	no	16.895	15.641	EPSD	COSMIC	16.704	Loss
AGC_PKC_PKCa_PRKCA_ST	Q14524	SCN5A	P17252	PRKCA	S581	P583S	583	Missense	proximal	2	no	16.895	17.478	EPSD	COSMIC	16.704	Up-regulation
AGC_PKC_PKCa_PRKCA_ST	Q14524	SCN5A	P17252	PRKCA	S581	G579R	579	Missense	proximal	-2	no	16.895	19.767	EPSD	COSMIC	16.704	Up-regulation
AGC_PKC_PKCa_PRKCA_ST	Q14524	SCN5A	P17252	PRKCA	S581	A582T	582	Missense	proximal	1	no	16.895	16.424	EPSD	COSMIC	16.704	Loss
AGC_PKC_PKCa_PRKCA_ST	Q14524	SCN5A	P17252	PRKCA	S1079	G1084S	1084	Missense	distal	5	no	16.643	16.783	EPSD	COSMIC	16.704	Gain
AGC_PKC_PKCa_PRKCA_ST	Q14524	SCN5A	P17252	PRKCA	S1079	Q1076K	1076	Missense	distal	-3	no	16.643	17.474	EPSD	COSMIC	16.704	Gain
AGC_PKC_PKCa_PRKCA_ST	Q14524	SCN5A	P17252	PRKCA	S1503	K1499T	1499	Missense	distal	-4	no	21.117	20.227	PhosphoSitePlus	COSMIC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	Q14524	SCN5A	P17252	PRKCA	T1895	R1897W	1897	Missense	proximal	2	no	17.236	11.796	EPSD	COSMIC;GDSC	16.704	Loss
AGC_PKC_PKCa_PRKCA_ST	Q14524	SCN5A	P17252	PRKCA	T1895	R1898P	1898	Missense	distal	3	no	17.236	15.705	EPSD	COSMIC	16.704	Loss
AGC_PKC_PKCa_PRKCA_ST	Q14524	SCN5A	P17252	PRKCA	T1895	R1897C	1897	Missense	proximal	2	no	17.236	12.886	EPSD	COSMIC	16.704	Loss
AGC_PKC_PKCa_PRKCA_ST	Q14524	SCN5A	P17252	PRKCA	T1895	R1897P	1897	Missense	proximal	2	no	17.236	12.033	EPSD	COSMIC	16.704	Loss
AGC_PKC_PKCa_PRKCA_ST	Q14524	SCN5A	P17252	PRKCA	S1920	R1913H	1913	Missense	distal	-7	no	20.164	20.157	EPSD	COSMIC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	Q14524	SCN5A	P17252	PRKCA	S1920	H1915P	1915	Missense	distal	-5	no	20.164	20.418	EPSD	COSMIC	16.704	Up-regulation
AGC_PKC_PKCa_PRKCA_ST	Q14524	SCN5A	P17252	PRKCA	S1920	R1913C	1913	Missense	distal	-7	no	20.164	20.145	EPSD	COSMIC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	Q14524	SCN5A	P17252	PRKCA	S1920	A1924V	1924	Missense	distal	4	no	20.164	18.826	EPSD	COSMIC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	Q14524	SCN5A	P17252	PRKCA	S1920	L1927F	1927	Missense	distal	7	no	20.164	20.098	EPSD	COSMIC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	P35900	KRT20	P17252	PRKCA	S11	L12M	12	Missense	proximal	1	no	18.157	17.943	EPSD	COSMIC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	P35900	KRT20	P17252	PRKCA	S11	S4R	4	Missense	distal	-7	no	18.157	18.163	EPSD	COSMIC	16.704	Up-regulation
AGC_PKC_PKCa_PRKCA_ST	P35900	KRT20	P17252	PRKCA	S13	L12M	12	Missense	proximal	-1	no	18.842	19.920	PhosphoSitePlus	COSMIC	16.704	Up-regulation
AGC_PKC_PKCa_PRKCA_ST	P35900	KRT20	P17252	PRKCA	S14	L12M	12	Missense	proximal	-2	no	16.717	17.423	EPSD	COSMIC	16.704	Up-regulation
AGC_PKC_PKCa_PRKCA_ST	P35900	KRT20	P17252	PRKCA	S15	L12M	12	Missense	distal	-3	no	15.533	16.916	EPSD	COSMIC	16.704	Gain
AGC_PKC_PKCa_PRKCA_ST	P35900	KRT20	P17252	PRKCA	S83	S83N	83	Missense	central	0	yes	18.907	0.000	EPSD	COSMIC	16.704	Loss
AGC_PKC_PKCa_PRKCA_ST	P35900	KRT20	P17252	PRKCA	S83	S83G	83	Missense	central	0	yes	18.907	0.000	EPSD	COSMIC	16.704	Loss
AGC_PKC_PKCa_PRKCA_ST	P35900	KRT20	P17252	PRKCA	S293	R291H	291	Missense	proximal	-2	no	18.661	14.107	EPSD	COSMIC	16.704	Loss
AGC_PKC_PKCa_PRKCA_ST	P35900	KRT20	P17252	PRKCA	S293	E288Q	288	Missense	distal	-5	no	18.661	18.816	EPSD	COSMIC	16.704	Up-regulation
AGC_PKC_PKCa_PRKCA_ST	Q71U36	TUBA1A	P17252	PRKCA	T82	H88R	88	Missense	distal	6	no	19.353	19.431	EPSD	COSMIC	16.704	Up-regulation
AGC_PKC_PKCa_PRKCA_ST	Q71U36	TUBA1A	P17252	PRKCA	T82	R84L	84	Missense	proximal	2	no	19.353	14.366	EPSD	COSMIC	16.704	Loss
AGC_PKC_PKCa_PRKCA_ST	Q71U36	TUBA1A	P17252	PRKCA	S158	K163N	163	Missense	distal	5	no	16.944	16.438	EPSD	COSMIC	16.704	Loss
AGC_PKC_PKCa_PRKCA_ST	Q71U36	TUBA1A	P17252	PRKCA	S158	K164R	164	Missense	distal	6	no	16.944	16.957	EPSD	COSMIC	16.704	Up-regulation
AGC_PKC_PKCa_PRKCA_ST	Q71U36	TUBA1A	P17252	PRKCA	S165	K163N	163	Missense	proximal	-2	no	17.652	16.084	PhosphoSitePlus	COSMIC	16.704	Loss
AGC_PKC_PKCa_PRKCA_ST	Q71U36	TUBA1A	P17252	PRKCA	S165	K164R	164	Missense	proximal	-1	no	17.652	17.595	PhosphoSitePlus	COSMIC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	P35398	RORA	P17252	PRKCA	S100	A105V	105	Missense	distal	5	no	21.247	20.863	PhosphoSitePlus	COSMIC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	P35398	RORA	P17252	PRKCA	S100	T106S	106	Missense	distal	6	no	21.247	21.296	PhosphoSitePlus	COSMIC	16.704	Up-regulation
AGC_PKC_PKCa_PRKCA_ST	P35398	RORA	P17252	PRKCA	S100	R98T	98	Missense	proximal	-2	no	21.247	18.354	PhosphoSitePlus	COSMIC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	P35398	RORA	P17252	PRKCA	S100	R99K	99	Missense	proximal	-1	no	21.247	21.304	PhosphoSitePlus	COSMIC	16.704	Up-regulation
AGC_PKC_PKCa_PRKCA_ST	P35398	RORA	P17252	PRKCA	S100	R98K	98	Missense	proximal	-2	no	21.247	19.620	PhosphoSitePlus	COSMIC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	Q01844	EWSR1	P17252	PRKCA	S259	S255C	255	Missense	distal	-4	no	17.340	16.190	EPSD	COSMIC	16.704	Loss
AGC_PKC_PKCa_PRKCA_ST	Q01844	EWSR1	P17252	PRKCA	S259	Y254F	254	Missense	distal	-5	no	17.340	17.525	EPSD	COSMIC	16.704	Up-regulation
AGC_PKC_PKCa_PRKCA_ST	Q01844	EWSR1	P17252	PRKCA	S259	S266L	266	Missense	distal	7	no	17.340	17.343	EPSD	COSMIC	16.704	Up-regulation
AGC_PKC_PKCa_PRKCA_ST	Q01844	EWSR1	P17252	PRKCA	S259	S259N	259	Missense	central	0	yes	17.340	0.000	EPSD	COSMIC	16.704	Loss
AGC_PKC_PKCa_PRKCA_ST	Q01844	EWSR1	P17252	PRKCA	S259	S265N	265	Missense	distal	6	no	17.340	17.238	EPSD	COSMIC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	Q01844	EWSR1	P17252	PRKCA	S259	S260N	260	Missense	proximal	1	no	17.340	17.387	EPSD	COSMIC;CCLE	16.704	Up-regulation
AGC_PKC_PKCa_PRKCA_ST	Q01844	EWSR1	P17252	PRKCA	S265	F267I	267	Missense	proximal	2	no	17.085	16.356	EPSD	COSMIC	16.704	Loss
AGC_PKC_PKCa_PRKCA_ST	Q01844	EWSR1	P17252	PRKCA	S265	R268L	268	Missense	distal	3	no	17.085	14.847	EPSD	COSMIC	16.704	Loss
AGC_PKC_PKCa_PRKCA_ST	Q01844	EWSR1	P17252	PRKCA	S265	Q269H	269	Missense	distal	4	no	17.085	17.020	EPSD	COSMIC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	Q01844	EWSR1	P17252	PRKCA	S265	S266L	266	Missense	proximal	1	no	17.085	17.911	EPSD	COSMIC	16.704	Up-regulation
AGC_PKC_PKCa_PRKCA_ST	Q01844	EWSR1	P17252	PRKCA	S265	S259N	259	Missense	distal	-6	no	17.085	17.028	EPSD	COSMIC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	Q01844	EWSR1	P17252	PRKCA	S265	S265N	265	Missense	central	0	yes	17.085	0.000	EPSD	COSMIC	16.704	Loss
AGC_PKC_PKCa_PRKCA_ST	Q01844	EWSR1	P17252	PRKCA	S265	S260N	260	Missense	distal	-5	no	17.085	17.156	EPSD	COSMIC;CCLE	16.704	Up-regulation
AGC_PKC_PKCa_PRKCA_ST	Q01844	EWSR1	P17252	PRKCA	S266	F267I	267	Missense	proximal	1	no	21.190	21.369	PhosphoSitePlus	COSMIC	16.704	Up-regulation
AGC_PKC_PKCa_PRKCA_ST	Q01844	EWSR1	P17252	PRKCA	S266	R268L	268	Missense	proximal	2	no	21.190	16.203	PhosphoSitePlus	COSMIC	16.704	Loss
AGC_PKC_PKCa_PRKCA_ST	Q01844	EWSR1	P17252	PRKCA	S266	Q269H	269	Missense	distal	3	no	21.190	22.931	PhosphoSitePlus	COSMIC	16.704	Up-regulation
AGC_PKC_PKCa_PRKCA_ST	Q01844	EWSR1	P17252	PRKCA	S266	S266L	266	Missense	central	0	yes	21.190	0.000	PhosphoSitePlus	COSMIC	16.704	Loss
AGC_PKC_PKCa_PRKCA_ST	Q01844	EWSR1	P17252	PRKCA	S266	S259N	259	Missense	distal	-7	no	21.190	21.185	PhosphoSitePlus	COSMIC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	Q01844	EWSR1	P17252	PRKCA	S266	S265N	265	Missense	proximal	-1	no	21.190	21.032	PhosphoSitePlus	COSMIC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	Q01844	EWSR1	P17252	PRKCA	S266	S260N	260	Missense	distal	-6	no	21.190	21.133	PhosphoSitePlus	COSMIC;CCLE	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	Q01844	EWSR1	P17252	PRKCA	S282	G279R	279	Missense	distal	-3	no	14.286	17.548	EPSD	COSMIC	16.704	Gain
AGC_PKC_PKCa_PRKCA_ST	Q15762	CD226	P17252	PRKCA	S329	R330C	330	Missense	proximal	1	no	16.809	13.973	PhosphoSitePlus	COSMIC	16.704	Loss
AGC_PKC_PKCa_PRKCA_ST	Q15762	CD226	P17252	PRKCA	S329	K333Q	333	Missense	distal	4	no	16.809	16.421	PhosphoSitePlus	COSMIC	16.704	Loss
AGC_PKC_PKCa_PRKCA_ST	Q15762	CD226	P17252	PRKCA	S329	Y325H	325	Missense	distal	-4	no	16.809	16.621	PhosphoSitePlus	COSMIC	16.704	Loss
AGC_PKC_PKCa_PRKCA_ST	P49840	GSK3A	P17252	PRKCA	S52	A51P	51	Missense	proximal	-1	no	17.680	17.939	EPSD	COSMIC	16.704	Up-regulation
AGC_PKC_PKCa_PRKCA_ST	P49840	GSK3A	P17252	PRKCA	S52	G49V	49	Missense	distal	-3	no	17.680	17.252	EPSD	COSMIC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	P49840	GSK3A	P17252	PRKCA	S97	V104I	104	Missense	distal	7	no	19.659	19.562	EPSD	COSMIC;GDSC;CCLE	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	P14416	DRD2	P17252	PRKCA	S19	P21R	21	Missense	proximal	2	no	12.543	17.746	EPSD	COSMIC	16.704	Gain
AGC_PKC_PKCa_PRKCA_ST	P14416	DRD2	P17252	PRKCA	S147	V154I	154	Missense	distal	7	no	22.313	22.216	EPSD	COSMIC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	P14416	DRD2	P17252	PRKCA	S147	V154F	154	Missense	distal	7	no	22.313	22.305	EPSD	COSMIC;CCLE	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	P14416	DRD2	P17252	PRKCA	S147	R145H	145	Missense	proximal	-2	no	22.313	17.759	EPSD	COSMIC;GDSC;CCLE	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	P14416	DRD2	P17252	PRKCA	S147	L141M	141	Missense	distal	-6	no	22.313	22.375	EPSD	COSMIC	16.704	Up-regulation
AGC_PKC_PKCa_PRKCA_ST	P14416	DRD2	P17252	PRKCA	S147	S147F	147	Missense	central	0	yes	22.313	0.000	EPSD	COSMIC	16.704	Loss
AGC_PKC_PKCa_PRKCA_ST	P14416	DRD2	P17252	PRKCA	S148	V154I	154	Missense	distal	6	no	22.832	22.887	EPSD	COSMIC	16.704	Up-regulation
AGC_PKC_PKCa_PRKCA_ST	P14416	DRD2	P17252	PRKCA	S148	V154F	154	Missense	distal	6	no	22.832	22.880	EPSD	COSMIC;CCLE	16.704	Up-regulation
AGC_PKC_PKCa_PRKCA_ST	P14416	DRD2	P17252	PRKCA	S148	R145H	145	Missense	distal	-3	no	22.832	18.976	EPSD	COSMIC;GDSC;CCLE	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	P14416	DRD2	P17252	PRKCA	S148	L141M	141	Missense	distal	-7	no	22.832	22.841	EPSD	COSMIC	16.704	Up-regulation
AGC_PKC_PKCa_PRKCA_ST	P14416	DRD2	P17252	PRKCA	S148	S147F	147	Missense	proximal	-1	no	22.832	22.125	EPSD	COSMIC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	P14416	DRD2	P17252	PRKCA	T225	R220C	220	Missense	distal	-5	no	21.887	21.211	EPSD	COSMIC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	P14416	DRD2	P17252	PRKCA	T225	R227H	227	Missense	proximal	2	no	21.887	16.863	EPSD	COSMIC;GDSC;CCLE	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	P14416	DRD2	P17252	PRKCA	T225	F232L	232	Missense	distal	7	no	21.887	21.953	EPSD	COSMIC	16.704	Up-regulation
AGC_PKC_PKCa_PRKCA_ST	P14416	DRD2	P17252	PRKCA	T225	R219S	219	Missense	distal	-6	no	21.887	21.813	EPSD	COSMIC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	P14416	DRD2	P17252	PRKCA	T225	R218H	218	Missense	distal	-7	no	21.887	21.880	EPSD	COSMIC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	P14416	DRD2	P17252	PRKCA	T225	R218S	218	Missense	distal	-7	no	21.887	21.881	EPSD	COSMIC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	P14416	DRD2	P17252	PRKCA	T225	R218C	218	Missense	distal	-7	no	21.887	21.868	EPSD	COSMIC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	P14416	DRD2	P17252	PRKCA	S228	R227H	227	Missense	proximal	-1	no	18.941	18.617	EPSD;PhosphoSitePlus	COSMIC;GDSC;CCLE	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	P14416	DRD2	P17252	PRKCA	S228	F232L	232	Missense	distal	4	no	18.941	18.510	EPSD;PhosphoSitePlus	COSMIC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	P14416	DRD2	P17252	PRKCA	S229	R227H	227	Missense	proximal	-2	no	17.910	13.356	PhosphoSitePlus;EPSD	COSMIC;GDSC;CCLE	16.704	Loss
AGC_PKC_PKCa_PRKCA_ST	P14416	DRD2	P17252	PRKCA	S229	F232L	232	Missense	distal	3	no	17.910	17.576	PhosphoSitePlus;EPSD	COSMIC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	P14416	DRD2	P17252	PRKCA	S296	P299H	299	Missense	distal	3	no	16.073	16.892	EPSD	COSMIC	16.704	Gain
AGC_PKC_PKCa_PRKCA_ST	P14416	DRD2	P17252	PRKCA	S354	R360C	360	Missense	distal	6	no	21.245	21.006	EPSD	COSMIC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	P14416	DRD2	P17252	PRKCA	S354	S354F	354	Missense	central	0	yes	21.245	0.000	EPSD	COSMIC	16.704	Loss
AGC_PKC_PKCa_PRKCA_ST	P14416	DRD2	P17252	PRKCA	S354	S359G	359	Missense	distal	5	no	21.245	21.105	EPSD	COSMIC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	P14416	DRD2	P17252	PRKCA	S354	R360H	360	Missense	distal	6	no	21.245	21.167	EPSD	COSMIC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	P14416	DRD2	P17252	PRKCA	S359	R360C	360	Missense	proximal	1	no	22.387	19.551	EPSD	COSMIC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	P14416	DRD2	P17252	PRKCA	S359	S354F	354	Missense	distal	-5	no	22.387	22.490	EPSD	COSMIC	16.704	Up-regulation
AGC_PKC_PKCa_PRKCA_ST	P14416	DRD2	P17252	PRKCA	S359	S359G	359	Missense	central	0	yes	22.387	0.000	EPSD	COSMIC	16.704	Loss
AGC_PKC_PKCa_PRKCA_ST	P14416	DRD2	P17252	PRKCA	S359	R360H	360	Missense	proximal	1	no	22.387	21.574	EPSD	COSMIC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	P49685	GPR15	P17252	PRKCA	S357	A351V	351	Missense	distal	-6	no	17.197	17.120	PhosphoSitePlus	COSMIC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	Q96QS3	ARX	P17252	PRKCA	S18	E15G	15	Missense	distal	-3	no	16.912	18.589	EPSD	COSMIC	16.704	Up-regulation
AGC_PKC_PKCa_PRKCA_ST	Q96QS3	ARX	P17252	PRKCA	S18	P14L	14	Missense	distal	-4	no	16.912	16.652	EPSD	COSMIC	16.704	Loss
AGC_PKC_PKCa_PRKCA_ST	Q96QS3	ARX	P17252	PRKCA	S37	P38S	38	Missense	proximal	1	no	17.590	17.191	EPSD	COSMIC;CCLE	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	Q96QS3	ARX	P17252	PRKCA	S37	R36M	36	Missense	proximal	-1	no	17.590	17.863	EPSD	COSMIC	16.704	Up-regulation
AGC_PKC_PKCa_PRKCA_ST	Q96QS3	ARX	P17252	PRKCA	S67	P60L	60	Missense	distal	-7	no	20.150	20.148	EPSD	COSMIC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	P08581	MET	P17252	PRKCA	S985	T992I	992	Missense	distal	7	no	18.504	18.344	PhosphoSitePlus	COSMIC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	P08581	MET	P17252	PRKCA	S985	V984A	984	Missense	proximal	-1	no	18.504	19.408	PhosphoSitePlus	COSMIC	16.704	Up-regulation
AGC_PKC_PKCa_PRKCA_ST	P08581	MET	P17252	PRKCA	S985	A986D	986	Missense	proximal	1	no	18.504	17.280	PhosphoSitePlus	COSMIC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	P08581	MET	P17252	PRKCA	S985	R987Q	987	Missense	proximal	2	no	18.504	14.670	PhosphoSitePlus	COSMIC	16.704	Loss
AGC_PKC_PKCa_PRKCA_ST	P08581	MET	P17252	PRKCA	S985	L980V	980	Missense	distal	-5	no	18.504	18.068	PhosphoSitePlus	COSMIC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	P08581	MET	P17252	PRKCA	S985	P991S	991	Missense	distal	6	no	18.504	18.471	PhosphoSitePlus	COSMIC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	P08581	MET	P17252	PRKCA	S985	P978S	978	Missense	distal	-7	no	18.504	18.507	PhosphoSitePlus	COSMIC	16.704	Up-regulation
AGC_PKC_PKCa_PRKCA_ST	P08581	MET	P17252	PRKCA	S1236	H1238R	1238	Missense	proximal	2	no	13.845	18.869	EPSD	COSMIC	16.704	Gain
AGC_PKC_PKCa_PRKCA_ST	P22460	KCNA5	P17252	PRKCA	S414	S414P	414	Missense	central	0	yes	17.936	0.000	EPSD	COSMIC;GDSC	16.704	Loss
AGC_PKC_PKCa_PRKCA_ST	P22460	KCNA5	P17252	PRKCA	S417	I422M	422	Missense	distal	5	no	17.099	17.420	EPSD	COSMIC	16.704	Up-regulation
AGC_PKC_PKCa_PRKCA_ST	P22460	KCNA5	P17252	PRKCA	S417	S414P	414	Missense	distal	-3	no	17.099	16.120	EPSD	COSMIC;GDSC	16.704	Loss
AGC_PKC_PKCa_PRKCA_ST	P22460	KCNA5	P17252	PRKCA	S430	A429T	429	Missense	proximal	-1	no	17.446	17.627	EPSD	COSMIC	16.704	Up-regulation
AGC_PKC_PKCa_PRKCA_ST	P22460	KCNA5	P17252	PRKCA	S557	F563L	563	Missense	distal	6	no	17.842	17.873	EPSD	COSMIC	16.704	Up-regulation
AGC_PKC_PKCa_PRKCA_ST	P22460	KCNA5	P17252	PRKCA	S557	Q553H	553	Missense	distal	-4	no	17.842	17.645	EPSD	COSMIC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	P22460	KCNA5	P17252	PRKCA	S575	L570P	570	Missense	distal	-5	no	18.442	18.468	EPSD	COSMIC	16.704	Up-regulation
AGC_PKC_PKCa_PRKCA_ST	P22460	KCNA5	P17252	PRKCA	S575	E571K	571	Missense	distal	-4	no	18.442	19.173	EPSD	COSMIC	16.704	Up-regulation
AGC_PKC_PKCa_PRKCA_ST	P22460	KCNA5	P17252	PRKCA	S575	R577L	577	Missense	proximal	2	no	18.442	13.455	EPSD	COSMIC	16.704	Loss
AGC_PKC_PKCa_PRKCA_ST	Q92837	FRAT1	P17252	PRKCA	S188	S188F	188	Missense	central	0	yes	22.212	0.000	PhosphoSitePlus	COSMIC	16.704	Loss
AGC_PKC_PKCa_PRKCA_ST	Q06481	APLP2	P17252	PRKCA	T723	G727E	727	Missense	distal	4	no	16.878	17.113	PhosphoSitePlus	COSMIC	16.704	Up-regulation
AGC_PKC_PKCa_PRKCA_ST	Q06481	APLP2	P17252	PRKCA	T723	I724S	724	Missense	proximal	1	no	16.878	15.215	PhosphoSitePlus	COSMIC	16.704	Loss
AGC_PKC_PKCa_PRKCA_ST	Q06481	APLP2	P17252	PRKCA	T723	G727R	727	Missense	distal	4	no	16.878	17.481	PhosphoSitePlus	COSMIC	16.704	Up-regulation
TK_Src_SRM_Y	Q13882	PTK6	Q9H3Y6	SRMS	Y114	S117P	117	Missense	distal	3	no	0.999	1.853	EPSD	COSMIC	1.179	Gain
TK_Src_SRM_Y	Q13882	PTK6	Q9H3Y6	SRMS	Y342	I337M	337	Missense	distal	-5	no	1.301	1.259	EPSD	COSMIC	1.179	Down-regulation
TK_Src_SRM_Y	Q13882	PTK6	Q9H3Y6	SRMS	Y342	R335S	335	Missense	distal	-7	no	1.301	1.388	EPSD	COSMIC	1.179	Up-regulation
TK_Src_SRM_Y	Q13882	PTK6	Q9H3Y6	SRMS	Y342	L343F	343	Missense	proximal	1	no	1.301	1.244	EPSD	COSMIC	1.179	Down-regulation
TK_Src_SRM_Y	Q13882	PTK6	Q9H3Y6	SRMS	Y447	P450L	450	Missense	distal	3	no	3.022	2.025	PhosphoSitePlus	COSMIC	1.179	Down-regulation
CAMK_CAMKL_BRSK_BRSK1_ST	P23258	TUBG1	Q8TDC3	BRSK1	S131	R124W	124	Missense	distal	-7	no	1.301	1.315	PhosphoSitePlus;EPSD	COSMIC	0.579	Up-regulation
Other_IKK_IKBKB_ST	Q9NQC7	CYLD	O14920	IKBKB	S62	P61H	61	Missense	proximal	-1	no	19.531	19.607	EPSD	COSMIC	16.613	Up-regulation
Other_IKK_IKBKB_ST	Q9NQC7	CYLD	O14920	IKBKB	S62	R59M	59	Missense	distal	-3	no	19.531	19.542	EPSD	COSMIC	16.613	Up-regulation
Other_IKK_IKBKB_ST	Q9NQC7	CYLD	O14920	IKBKB	S111	R109S	109	Missense	proximal	-2	no	21.767	21.991	EPSD	COSMIC	16.613	Up-regulation
Other_IKK_IKBKB_ST	Q9NQC7	CYLD	O14920	IKBKB	S362	G360L	360	Missense	proximal	-2	no	17.645	17.704	EPSD	COSMIC	16.613	Up-regulation
Other_IKK_IKBKB_ST	Q9NQC7	CYLD	O14920	IKBKB	S362	S365L	365	Missense	distal	3	no	17.645	14.694	EPSD	COSMIC	16.613	Loss
Other_IKK_IKBKB_ST	Q9NQC7	CYLD	O14920	IKBKB	S362	P367S	367	Missense	distal	5	no	17.645	17.846	EPSD	COSMIC	16.613	Up-regulation
Other_IKK_IKBKB_ST	Q9NQC7	CYLD	O14920	IKBKB	S362	S362L	362	Missense	central	0	yes	17.645	0.000	EPSD	COSMIC	16.613	Loss
Other_IKK_IKBKB_ST	Q9NQC7	CYLD	O14920	IKBKB	S418	E413K	413	Missense	distal	-5	no	21.328	21.334	EPSD;PhosphoSitePlus	COSMIC	16.613	Up-regulation
Other_IKK_IKBKB_ST	Q9NQC7	CYLD	O14920	IKBKB	S418	N414S	414	Missense	distal	-4	no	21.328	25.034	EPSD;PhosphoSitePlus	COSMIC	16.613	Up-regulation
Other_IKK_IKBKB_ST	Q9NQC7	CYLD	O14920	IKBKB	S432	G431E	431	Missense	proximal	-1	no	20.183	19.761	PhosphoSitePlus;EPSD	COSMIC	16.613	Down-regulation
Other_IKK_IKBKB_ST	Q9NQC7	CYLD	O14920	IKBKB	S436	G431E	431	Missense	distal	-5	no	22.593	22.684	EPSD;PhosphoSitePlus	COSMIC	16.613	Up-regulation
Other_IKK_IKBKB_ST	Q9NQC7	CYLD	O14920	IKBKB	S436	Q443K	443	Missense	distal	7	no	22.593	22.867	EPSD;PhosphoSitePlus	COSMIC	16.613	Up-regulation
Other_IKK_IKBKB_ST	Q9NQC7	CYLD	O14920	IKBKB	S439	Q443K	443	Missense	distal	4	no	20.831	20.478	EPSD;PhosphoSitePlus	COSMIC	16.613	Down-regulation
Other_IKK_IKBKB_ST	Q9NQC7	CYLD	O14920	IKBKB	S441	Q443K	443	Missense	proximal	2	no	20.238	20.902	EPSD;PhosphoSitePlus	COSMIC	16.613	Up-regulation
Other_IKK_IKBKB_ST	Q9NQC7	CYLD	O14920	IKBKB	S444	Q443K	443	Missense	proximal	-1	no	20.149	19.602	EPSD;PhosphoSitePlus	COSMIC	16.613	Down-regulation
Other_IKK_IKBKB_ST	Q99704	DOK1	O14920	IKBKB	S192	V188L	188	Missense	distal	-4	no	19.117	22.721	EPSD	COSMIC	16.613	Up-regulation
Other_IKK_IKBKB_ST	Q99704	DOK1	O14920	IKBKB	S192	E196D	196	Missense	distal	4	no	19.117	14.331	EPSD	COSMIC	16.613	Loss
Other_IKK_IKBKB_ST	Q99704	DOK1	O14920	IKBKB	S281	P285S	285	Missense	distal	4	no	17.935	20.135	EPSD	COSMIC	16.613	Up-regulation
Other_IKK_IKBKB_ST	Q99704	DOK1	O14920	IKBKB	S281	G284R	284	Missense	distal	3	no	17.935	17.827	EPSD	COSMIC	16.613	Down-regulation
Other_IKK_IKBKB_ST	Q99704	DOK1	O14920	IKBKB	S281	G284V	284	Missense	distal	3	no	17.935	13.846	EPSD	COSMIC	16.613	Loss
Other_IKK_IKBKB_ST	Q99704	DOK1	O14920	IKBKB	S281	P280L	280	Missense	proximal	-1	no	17.935	17.779	EPSD	COSMIC	16.613	Down-regulation
Other_IKK_IKBKB_ST	Q99704	DOK1	O14920	IKBKB	S281	P282L	282	Missense	proximal	1	no	17.935	17.643	EPSD	COSMIC	16.613	Down-regulation
Other_IKK_IKBKB_ST	Q99704	DOK1	O14920	IKBKB	S302	P307L	307	Missense	distal	5	no	20.031	20.308	EPSD	COSMIC	16.613	Up-regulation
Other_IKK_IKBKB_ST	Q99704	DOK1	O14920	IKBKB	S302	S302F	302	Missense	central	0	yes	20.031	0.000	EPSD	COSMIC	16.613	Loss
Other_IKK_IKBKB_ST	Q99704	DOK1	O14920	IKBKB	S302	P299L	299	Missense	distal	-3	no	20.031	20.170	EPSD	COSMIC	16.613	Up-regulation
Other_IKK_IKBKB_ST	Q99704	DOK1	O14920	IKBKB	S313	P307L	307	Missense	distal	-6	no	18.244	17.869	EPSD	COSMIC	16.613	Down-regulation
Other_IKK_IKBKB_ST	Q99704	DOK1	O14920	IKBKB	S313	D320N	320	Missense	distal	7	no	18.244	18.260	EPSD	COSMIC	16.613	Up-regulation
Other_IKK_IKBKB_ST	Q99704	DOK1	O14920	IKBKB	S321	D320N	320	Missense	proximal	-1	no	17.906	17.460	EPSD	COSMIC	16.613	Down-regulation
Other_IKK_IKBKB_ST	Q99704	DOK1	O14920	IKBKB	S439	G440D	440	Missense	proximal	1	no	17.216	15.965	EPSD;PhosphoSitePlus	COSMIC	16.613	Loss
Other_IKK_IKBKB_ST	Q99704	DOK1	O14920	IKBKB	S439	T437A	437	Missense	proximal	-2	no	17.216	16.999	EPSD;PhosphoSitePlus	COSMIC	16.613	Down-regulation
Other_IKK_IKBKB_ST	Q99704	DOK1	O14920	IKBKB	S439	H444D	444	Missense	distal	5	no	17.216	16.577	EPSD;PhosphoSitePlus	COSMIC	16.613	Loss
Other_IKK_IKBKB_ST	Q99704	DOK1	O14920	IKBKB	S443	G440D	440	Missense	distal	-3	no	27.181	27.193	EPSD;PhosphoSitePlus	COSMIC	16.613	Up-regulation
Other_IKK_IKBKB_ST	Q99704	DOK1	O14920	IKBKB	S443	T437A	437	Missense	distal	-6	no	27.181	27.327	EPSD;PhosphoSitePlus	COSMIC	16.613	Up-regulation
Other_IKK_IKBKB_ST	Q99704	DOK1	O14920	IKBKB	S443	H444D	444	Missense	proximal	1	no	27.181	26.456	EPSD;PhosphoSitePlus	COSMIC	16.613	Down-regulation
Other_IKK_IKBKB_ST	Q99704	DOK1	O14920	IKBKB	S443	A447V	447	Missense	distal	4	no	27.181	24.491	EPSD;PhosphoSitePlus	COSMIC	16.613	Down-regulation
Other_IKK_IKBKB_ST	Q99704	DOK1	O14920	IKBKB	S446	G440D	440	Missense	distal	-6	no	19.754	20.227	PhosphoSitePlus;EPSD	COSMIC	16.613	Up-regulation
Other_IKK_IKBKB_ST	Q99704	DOK1	O14920	IKBKB	S446	H444D	444	Missense	proximal	-2	no	19.754	19.059	PhosphoSitePlus;EPSD	COSMIC	16.613	Down-regulation
Other_IKK_IKBKB_ST	Q99704	DOK1	O14920	IKBKB	S446	A447V	447	Missense	proximal	1	no	19.754	20.093	PhosphoSitePlus;EPSD	COSMIC	16.613	Up-regulation
Other_IKK_IKBKB_ST	Q99704	DOK1	O14920	IKBKB	S450	H444D	444	Missense	distal	-6	no	21.826	21.714	EPSD;PhosphoSitePlus	COSMIC	16.613	Down-regulation
Other_IKK_IKBKB_ST	Q99704	DOK1	O14920	IKBKB	S450	A447V	447	Missense	distal	-3	no	21.826	21.367	EPSD;PhosphoSitePlus	COSMIC	16.613	Down-regulation
Other_IKK_IKBKB_ST	Q99704	DOK1	O14920	IKBKB	S466	D471A	471	Missense	distal	5	no	18.191	20.493	EPSD	COSMIC;GDSC	16.613	Up-regulation
Other_IKK_IKBKB_ST	Q99704	DOK1	O14920	IKBKB	S466	T470N	470	Missense	distal	4	no	18.191	18.828	EPSD	COSMIC	16.613	Up-regulation
Other_IKK_IKBKB_ST	Q99704	DOK1	O14920	IKBKB	S466	D471G	471	Missense	distal	5	no	18.191	16.866	EPSD	COSMIC	16.613	Down-regulation
Other_IKK_IKBKB_ST	Q04206	RELA	O14920	IKBKB	S45	E39Q	39	Missense	distal	-6	no	17.029	15.695	EPSD;PhosphoSitePlus	COSMIC	16.613	Loss
Other_IKK_IKBKB_ST	Q04206	RELA	O14920	IKBKB	S112	Q119K	119	Missense	distal	7	no	18.249	18.523	EPSD	COSMIC	16.613	Up-regulation
Other_IKK_IKBKB_ST	Q04206	RELA	O14920	IKBKB	S112	H111Y	111	Missense	proximal	-1	no	18.249	18.762	EPSD	COSMIC	16.613	Up-regulation
Other_IKK_IKBKB_ST	Q04206	RELA	O14920	IKBKB	S131	R124W	124	Missense	distal	-7	no	21.693	17.682	PhosphoSitePlus;EPSD	COSMIC	16.613	Down-regulation
Other_IKK_IKBKB_ST	Q04206	RELA	O14920	IKBKB	S261	R267C	267	Missense	distal	6	no	17.978	19.076	EPSD;PhosphoSitePlus	COSMIC	16.613	Up-regulation
Other_IKK_IKBKB_ST	Q04206	RELA	O14920	IKBKB	S261	P256H	256	Missense	distal	-5	no	17.978	18.002	EPSD;PhosphoSitePlus	COSMIC	16.613	Up-regulation
Other_IKK_IKBKB_ST	Q04206	RELA	O14920	IKBKB	S311	M313I	313	Missense	proximal	2	no	29.249	28.013	EPSD;PhosphoSitePlus	COSMIC	16.613	Down-regulation
Other_IKK_IKBKB_ST	Q04206	RELA	O14920	IKBKB	S311	K314N	314	Missense	distal	3	no	29.249	29.744	EPSD;PhosphoSitePlus	COSMIC	16.613	Up-regulation
Other_IKK_IKBKB_ST	Q04206	RELA	O14920	IKBKB	S311	T305A	305	Missense	distal	-6	no	29.249	29.394	EPSD;PhosphoSitePlus	COSMIC	16.613	Up-regulation
Other_IKK_IKBKB_ST	Q04206	RELA	O14920	IKBKB	S529	F534L	534	Missense	distal	5	no	15.913	17.934	EPSD	COSMIC	16.613	Gain
Other_IKK_IKBKB_ST	Q04206	RELA	O14920	IKBKB	S536	F534L	534	Missense	proximal	-2	no	35.152	35.185	EPSD;PhosphoSitePlus	COSMIC	16.613	Up-regulation
Other_IKK_IKBKB_ST	O15350	TP73	O14920	IKBKB	S471	S468N	468	Missense	distal	-3	no	22.729	23.106	PhosphoSitePlus	COSMIC	16.613	Up-regulation
Other_IKK_IKBKB_ST	O15350	TP73	O14920	IKBKB	S471	S474P	474	Missense	distal	3	no	22.729	21.394	PhosphoSitePlus	COSMIC	16.613	Down-regulation
Other_IKK_IKBKB_ST	O15350	TP73	O14920	IKBKB	S471	G478R	478	Missense	distal	7	no	22.729	23.215	PhosphoSitePlus	COSMIC;CCLE	16.613	Up-regulation
Other_IKK_IKBKB_ST	O15350	TP73	O14920	IKBKB	S471	G464S	464	Missense	distal	-7	no	22.729	22.508	PhosphoSitePlus	COSMIC	16.613	Down-regulation
Other_IKK_IKBKB_ST	Q9H3D4	TP63	O14920	IKBKB	S30	E24K	24	Missense	distal	-6	no	26.086	25.909	EPSD	COSMIC	16.613	Down-regulation
Other_IKK_IKBKB_ST	Q9H3D4	TP63	O14920	IKBKB	S30	P26A	26	Missense	distal	-4	no	26.086	25.467	EPSD	COSMIC	16.613	Down-regulation
Other_IKK_IKBKB_ST	Q9H3D4	TP63	O14920	IKBKB	S30	H28D	28	Missense	proximal	-2	no	26.086	25.391	EPSD	COSMIC	16.613	Down-regulation
Other_IKK_IKBKB_ST	Q9H3D4	TP63	O14920	IKBKB	S30	Y35F	35	Missense	distal	5	no	26.086	28.245	EPSD	COSMIC	16.613	Up-regulation
Other_IKK_IKBKB_ST	Q9H3D4	TP63	O14920	IKBKB	S30	S34A	34	Missense	distal	4	no	26.086	23.534	EPSD	COSMIC	16.613	Down-regulation
Other_IKK_IKBKB_ST	Q9H3D4	TP63	O14920	IKBKB	S30	S34F	34	Missense	distal	4	no	26.086	22.473	EPSD	COSMIC	16.613	Down-regulation
Other_IKK_IKBKB_ST	Q9H3D4	TP63	O14920	IKBKB	S30	A27T	27	Missense	distal	-3	no	26.086	26.034	EPSD	COSMIC	16.613	Down-regulation
Other_IKK_IKBKB_ST	Q9H3D4	TP63	O14920	IKBKB	S43	E48K	48	Missense	distal	5	no	18.071	18.934	EPSD;PhosphoSitePlus	COSMIC	16.613	Up-regulation
Other_IKK_IKBKB_ST	Q9H3D4	TP63	O14920	IKBKB	S43	T39A	39	Missense	distal	-4	no	18.071	17.630	EPSD;PhosphoSitePlus	COSMIC	16.613	Down-regulation
Other_IKK_IKBKB_ST	Q9H3D4	TP63	O14920	IKBKB	S43	M40V	40	Missense	distal	-3	no	18.071	17.572	EPSD;PhosphoSitePlus	COSMIC	16.613	Down-regulation
Other_IKK_IKBKB_ST	Q9H3D4	TP63	O14920	IKBKB	S43	L50F	50	Missense	distal	7	no	18.071	17.568	EPSD;PhosphoSitePlus	COSMIC	16.613	Down-regulation
Other_IKK_IKBKB_ST	Q9H3D4	TP63	O14920	IKBKB	S43	S41F	41	Missense	proximal	-2	no	18.071	18.810	EPSD;PhosphoSitePlus	COSMIC	16.613	Up-regulation
Other_IKK_IKBKB_ST	Q9H3D4	TP63	O14920	IKBKB	S43	Q42E	42	Missense	proximal	-1	no	18.071	17.584	EPSD;PhosphoSitePlus	COSMIC	16.613	Down-regulation
Other_IKK_IKBKB_ST	Q9H3D4	TP63	O14920	IKBKB	S51	E48K	48	Missense	distal	-3	no	17.904	18.296	PhosphoSitePlus;EPSD	COSMIC	16.613	Up-regulation
Other_IKK_IKBKB_ST	Q9H3D4	TP63	O14920	IKBKB	S51	S51N	51	Missense	central	0	yes	17.904	0.000	PhosphoSitePlus;EPSD	COSMIC	16.613	Loss
Other_IKK_IKBKB_ST	Q9H3D4	TP63	O14920	IKBKB	S51	F55V	55	Missense	distal	4	no	17.904	16.275	PhosphoSitePlus;EPSD	COSMIC	16.613	Loss
Other_IKK_IKBKB_ST	Q9H3D4	TP63	O14920	IKBKB	S51	F55L	55	Missense	distal	4	no	17.904	19.672	PhosphoSitePlus;EPSD	COSMIC	16.613	Up-regulation
Other_IKK_IKBKB_ST	Q9H3D4	TP63	O14920	IKBKB	S51	L50F	50	Missense	proximal	-1	no	17.904	18.513	PhosphoSitePlus;EPSD	COSMIC	16.613	Up-regulation
Other_IKK_IKBKB_ST	Q9H3D4	TP63	O14920	IKBKB	S51	P52L	52	Missense	proximal	1	no	17.904	17.612	PhosphoSitePlus;EPSD	COSMIC	16.613	Down-regulation
Other_IKK_IKBKB_ST	Q9H3D4	TP63	O14920	IKBKB	S51	H57R	57	Missense	distal	6	no	17.904	17.894	PhosphoSitePlus;EPSD	COSMIC	16.613	Down-regulation
Other_IKK_IKBKB_ST	Q9H3D4	TP63	O14920	IKBKB	S395	K392E	392	Missense	distal	-3	no	23.136	22.744	EPSD	COSMIC	16.613	Down-regulation
Other_IKK_IKBKB_ST	Q9H3D4	TP63	O14920	IKBKB	S395	S395F	395	Missense	central	0	yes	23.136	0.000	EPSD	COSMIC;GDSC	16.613	Loss
Other_IKK_IKBKB_ST	Q9H3D4	TP63	O14920	IKBKB	S458	Q454H	454	Missense	distal	-4	no	16.559	18.115	EPSD	COSMIC	16.613	Gain
Other_IKK_IKBKB_ST	Q9H3D4	TP63	O14920	IKBKB	S458	S455T	455	Missense	distal	-3	no	16.559	16.638	EPSD	COSMIC	16.613	Gain
Other_IKK_IKBKB_ST	Q9H3D4	TP63	O14920	IKBKB	S458	Q454R	454	Missense	distal	-4	no	16.559	17.812	EPSD	COSMIC	16.613	Gain
Other_IKK_IKBKB_ST	Q9H3D4	TP63	O14920	IKBKB	S458	S457G	457	Missense	proximal	-1	no	16.559	16.949	EPSD	COSMIC	16.613	Gain
Other_IKK_IKBKB_ST	Q9H3D4	TP63	O14920	IKBKB	S462	N467K	467	Missense	distal	5	no	14.183	18.170	EPSD	COSMIC	16.613	Gain
Other_IKK_IKBKB_ST	Q9H3D4	TP63	O14920	IKBKB	S612	R618W	618	Missense	distal	6	no	17.344	18.637	EPSD	COSMIC;GDSC;CCLE	16.613	Up-regulation
Other_IKK_IKBKB_ST	Q9H3D4	TP63	O14920	IKBKB	S612	R605Q	605	Missense	distal	-7	no	17.344	15.817	EPSD	COSMIC;GDSC	16.613	Loss
Other_IKK_IKBKB_ST	Q9H3D4	TP63	O14920	IKBKB	S612	R618Q	618	Missense	distal	6	no	17.344	17.696	EPSD	COSMIC	16.613	Up-regulation
Other_IKK_IKBKB_ST	Q9H3D4	TP63	O14920	IKBKB	S612	R605W	605	Missense	distal	-7	no	17.344	13.334	EPSD	COSMIC	16.613	Loss
Other_IKK_IKBKB_ST	Q9H3D4	TP63	O14920	IKBKB	S612	S612F	612	Missense	central	0	yes	17.344	0.000	EPSD	COSMIC	16.613	Loss
Other_IKK_IKBKB_ST	Q9H3D4	TP63	O14920	IKBKB	S612	P613L	613	Missense	proximal	1	no	17.344	17.052	EPSD	COSMIC	16.613	Down-regulation
Other_IKK_IKBKB_ST	Q9H3D4	TP63	O14920	IKBKB	S612	H615D	615	Missense	distal	3	no	17.344	17.693	EPSD	COSMIC	16.613	Up-regulation
Other_IKK_IKBKB_ST	Q9H3D4	TP63	O14920	IKBKB	S612	P613T	613	Missense	proximal	1	no	17.344	15.582	EPSD	COSMIC	16.613	Loss
Other_IKK_IKBKB_ST	Q9H3D4	TP63	O14920	IKBKB	S612	H608Q	608	Missense	distal	-4	no	17.344	15.788	EPSD	COSMIC	16.613	Loss
Other_IKK_IKBKB_ST	Q9H3D4	TP63	O14920	IKBKB	S622	V626F	626	Missense	distal	4	no	15.034	16.663	EPSD	COSMIC	16.613	Gain
Other_IKK_IKBKB_ST	P19838	NFKB1	O14920	IKBKB	S449	D447G	447	Missense	proximal	-2	no	18.785	19.900	EPSD	COSMIC	16.613	Up-regulation
Other_IKK_IKBKB_ST	P19838	NFKB1	O14920	IKBKB	S923	E930K	930	Missense	distal	7	no	17.501	17.205	PhosphoSitePlus;EPSD	COSMIC	16.613	Down-regulation
Other_IKK_IKBKB_ST	P19838	NFKB1	O14920	IKBKB	S927	R934H	934	Missense	distal	7	no	22.993	22.744	EPSD;PhosphoSitePlus	COSMIC	16.613	Down-regulation
Other_IKK_IKBKB_ST	P19838	NFKB1	O14920	IKBKB	S927	E930K	930	Missense	distal	3	no	22.993	21.964	EPSD;PhosphoSitePlus	COSMIC	16.613	Down-regulation
Other_IKK_IKBKB_ST	P19838	NFKB1	O14920	IKBKB	S932	R934H	934	Missense	proximal	2	no	19.445	19.423	EPSD;PhosphoSitePlus	COSMIC	16.613	Down-regulation
Other_IKK_IKBKB_ST	P19838	NFKB1	O14920	IKBKB	S932	E930K	930	Missense	proximal	-2	no	19.445	19.211	EPSD;PhosphoSitePlus	COSMIC	16.613	Down-regulation
Other_IKK_IKBKB_ST	P19838	NFKB1	O14920	IKBKB	S932	T939I	939	Missense	distal	7	no	19.445	19.109	EPSD;PhosphoSitePlus	COSMIC	16.613	Down-regulation
Other_IKK_IKBKB_ST	P19838	NFKB1	O14920	IKBKB	S941	R934H	934	Missense	distal	-7	no	18.040	16.846	EPSD	COSMIC	16.613	Down-regulation
Other_IKK_IKBKB_ST	P19838	NFKB1	O14920	IKBKB	S941	S947L	947	Missense	distal	6	no	18.040	19.248	EPSD	COSMIC	16.613	Up-regulation
Other_IKK_IKBKB_ST	P19838	NFKB1	O14920	IKBKB	S941	T939I	939	Missense	proximal	-2	no	18.040	18.572	EPSD	COSMIC	16.613	Up-regulation
Other_IKK_IKBKB_ST	P19838	NFKB1	O14920	IKBKB	S944	S947L	947	Missense	distal	3	no	25.368	22.417	EPSD	COSMIC	16.613	Down-regulation
Other_IKK_IKBKB_ST	P19838	NFKB1	O14920	IKBKB	S944	L951F	951	Missense	distal	7	no	25.368	24.865	EPSD	COSMIC	16.613	Down-regulation
Other_IKK_IKBKB_ST	P19838	NFKB1	O14920	IKBKB	S944	T939I	939	Missense	distal	-5	no	25.368	25.004	EPSD	COSMIC	16.613	Down-regulation
Other_IKK_IKBKB_ST	P25963	NFKBIA	O14920	IKBKB	S32	M37K	37	Missense	distal	5	no	36.028	35.581	EPSD;PhosphoSitePlus	COSMIC	16.613	Down-regulation
Other_IKK_IKBKB_ST	P25963	NFKBIA	O14920	IKBKB	S32	S36P	36	Missense	distal	4	no	36.028	33.829	EPSD;PhosphoSitePlus	COSMIC	16.613	Down-regulation
Other_IKK_IKBKB_ST	P25963	NFKBIA	O14920	IKBKB	S32	S32N	32	Missense	central	0	yes	36.028	0.000	EPSD;PhosphoSitePlus	COSMIC	16.613	Loss
Other_IKK_IKBKB_ST	P25963	NFKBIA	O14920	IKBKB	S36	M37K	37	Missense	proximal	1	no	37.410	36.136	PhosphoSitePlus;EPSD	COSMIC	16.613	Down-regulation
Other_IKK_IKBKB_ST	P25963	NFKBIA	O14920	IKBKB	S36	E40D	40	Missense	distal	4	no	37.410	32.624	PhosphoSitePlus;EPSD	COSMIC	16.613	Down-regulation
Other_IKK_IKBKB_ST	P25963	NFKBIA	O14920	IKBKB	S36	E43K	43	Missense	distal	7	no	37.410	37.114	PhosphoSitePlus;EPSD	COSMIC	16.613	Down-regulation
Other_IKK_IKBKB_ST	P25963	NFKBIA	O14920	IKBKB	S36	S36P	36	Missense	central	0	yes	37.410	0.000	PhosphoSitePlus;EPSD	COSMIC	16.613	Loss
Other_IKK_IKBKB_ST	P25963	NFKBIA	O14920	IKBKB	S36	E43Q	43	Missense	distal	7	no	37.410	36.840	PhosphoSitePlus;EPSD	COSMIC	16.613	Down-regulation
Other_IKK_IKBKB_ST	P25963	NFKBIA	O14920	IKBKB	S36	S32N	32	Missense	distal	-4	no	37.410	33.705	PhosphoSitePlus;EPSD	COSMIC	16.613	Down-regulation
Other_IKK_IKBKB_ST	P25963	NFKBIA	O14920	IKBKB	S283	E284D	284	Missense	proximal	1	no	17.052	16.486	EPSD	COSMIC	16.613	Loss
Other_IKK_IKBKB_ST	P25963	NFKBIA	O14920	IKBKB	S283	E287V	287	Missense	distal	4	no	17.052	9.875	EPSD	COSMIC	16.613	Loss
Other_IKK_IKBKB_ST	P25963	NFKBIA	O14920	IKBKB	S283	Y289C	289	Missense	distal	6	no	17.052	16.809	EPSD	COSMIC	16.613	Down-regulation
Other_IKK_IKBKB_ST	P25963	NFKBIA	O14920	IKBKB	S283	N276K	276	Missense	distal	-7	no	17.052	16.135	EPSD	COSMIC	16.613	Loss
Other_IKK_IKBKB_ST	P25963	NFKBIA	O14920	IKBKB	S288	T291K	291	Missense	distal	3	no	17.602	17.326	EPSD	COSMIC	16.613	Down-regulation
Other_IKK_IKBKB_ST	P25963	NFKBIA	O14920	IKBKB	S288	E284D	284	Missense	distal	-4	no	17.602	16.399	EPSD	COSMIC	16.613	Loss
Other_IKK_IKBKB_ST	P25963	NFKBIA	O14920	IKBKB	S288	T291P	291	Missense	distal	3	no	17.602	17.260	EPSD	COSMIC	16.613	Down-regulation
Other_IKK_IKBKB_ST	P25963	NFKBIA	O14920	IKBKB	S288	E287V	287	Missense	proximal	-1	no	17.602	17.895	EPSD	COSMIC	16.613	Up-regulation
Other_IKK_IKBKB_ST	P25963	NFKBIA	O14920	IKBKB	S288	Y289C	289	Missense	proximal	1	no	17.602	17.093	EPSD	COSMIC	16.613	Down-regulation
Other_IKK_IKBKB_ST	P25963	NFKBIA	O14920	IKBKB	S293	T291P	291	Missense	proximal	-2	no	16.254	17.367	EPSD	COSMIC	16.613	Gain
Other_IKK_IKBKB_ST	Q14653	IRF3	O14920	IKBKB	S339	G335E	335	Missense	distal	-4	no	19.611	27.185	EPSD	COSMIC	16.613	Up-regulation
Other_IKK_IKBKB_ST	Q14653	IRF3	O14920	IKBKB	S339	R341C	341	Missense	proximal	2	no	19.611	19.407	EPSD	COSMIC	16.613	Down-regulation
Other_IKK_IKBKB_ST	Q14653	IRF3	O14920	IKBKB	S339	G337A	337	Missense	proximal	-2	no	19.611	18.454	EPSD	COSMIC	16.613	Down-regulation
Other_IKK_IKBKB_ST	Q14653	IRF3	O14920	IKBKB	S339	G335V	335	Missense	distal	-4	no	19.611	15.650	EPSD	COSMIC	16.613	Loss
Other_IKK_IKBKB_ST	Q14653	IRF3	O14920	IKBKB	S396	T390I	390	Missense	distal	-6	no	28.361	27.252	EPSD;PhosphoSitePlus	COSMIC	16.613	Down-regulation
Other_IKK_IKBKB_ST	Q14653	IRF3	O14920	IKBKB	S396	T390P	390	Missense	distal	-6	no	28.361	28.203	EPSD;PhosphoSitePlus	COSMIC	16.613	Down-regulation
Other_IKK_IKBKB_ST	Q14653	IRF3	O14920	IKBKB	S396	P400Q	400	Missense	distal	4	no	28.361	29.990	EPSD;PhosphoSitePlus	COSMIC	16.613	Up-regulation
Other_IKK_IKBKB_ST	Q14653	IRF3	O14920	IKBKB	S396	P400T	400	Missense	distal	4	no	28.361	27.057	EPSD;PhosphoSitePlus	COSMIC	16.613	Down-regulation
Other_IKK_IKBKB_ST	Q14653	IRF3	O14920	IKBKB	S402	D406E	406	Missense	distal	4	no	21.526	26.313	EPSD;PhosphoSitePlus	COSMIC	16.613	Up-regulation
Other_IKK_IKBKB_ST	Q14653	IRF3	O14920	IKBKB	S402	P400Q	400	Missense	proximal	-2	no	21.526	20.823	EPSD;PhosphoSitePlus	COSMIC	16.613	Down-regulation
Other_IKK_IKBKB_ST	Q14653	IRF3	O14920	IKBKB	S402	P400T	400	Missense	proximal	-2	no	21.526	20.413	EPSD;PhosphoSitePlus	COSMIC	16.613	Down-regulation
Other_IKK_IKBKB_ST	Q14653	IRF3	O14920	IKBKB	S405	Y411S	411	Missense	distal	6	no	21.688	19.723	EPSD;PhosphoSitePlus	COSMIC	16.613	Down-regulation
Other_IKK_IKBKB_ST	Q14653	IRF3	O14920	IKBKB	S405	D406E	406	Missense	proximal	1	no	21.688	22.255	EPSD;PhosphoSitePlus	COSMIC	16.613	Up-regulation
Other_IKK_IKBKB_ST	Q14653	IRF3	O14920	IKBKB	S405	P400Q	400	Missense	distal	-5	no	21.688	21.118	EPSD;PhosphoSitePlus	COSMIC	16.613	Down-regulation
Other_IKK_IKBKB_ST	Q14653	IRF3	O14920	IKBKB	S405	P400T	400	Missense	distal	-5	no	21.688	21.692	EPSD;PhosphoSitePlus	COSMIC	16.613	Up-regulation
Other_IKK_IKBKB_ST	P01100	FOS	O14920	IKBKB	S258	S258I	258	Missense	central	0	yes	25.711	0.000	EPSD	COSMIC	16.613	Loss
Other_IKK_IKBKB_ST	P01100	FOS	O14920	IKBKB	S261	S258I	258	Missense	distal	-3	no	23.494	22.559	EPSD	COSMIC	16.613	Down-regulation
Other_IKK_IKBKB_ST	P01100	FOS	O14920	IKBKB	S281	A286T	286	Missense	distal	5	no	18.030	16.992	EPSD	COSMIC	16.613	Down-regulation
Other_IKK_IKBKB_ST	P01100	FOS	O14920	IKBKB	S283	P290S	290	Missense	distal	7	no	16.307	17.023	EPSD	COSMIC	16.613	Gain
Other_IKK_IKBKB_ST	P01100	FOS	O14920	IKBKB	S283	A286T	286	Missense	distal	3	no	16.307	16.756	EPSD	COSMIC	16.613	Gain
Other_IKK_IKBKB_ST	P01100	FOS	O14920	IKBKB	S308	P315S	315	Missense	distal	7	no	27.703	28.419	PhosphoSitePlus	COSMIC	16.613	Up-regulation
Other_IKK_IKBKB_ST	P01100	FOS	O14920	IKBKB	S308	G312W	312	Missense	distal	4	no	27.703	24.292	PhosphoSitePlus	COSMIC	16.613	Down-regulation
Other_IKK_IKBKB_ST	P01100	FOS	O14920	IKBKB	S362	S364I	364	Missense	proximal	2	no	19.817	19.532	EPSD	COSMIC;GDSC;CCLE	16.613	Down-regulation
Other_IKK_IKBKB_ST	P01100	FOS	O14920	IKBKB	S364	S371T	371	Missense	distal	7	no	24.792	24.183	EPSD	COSMIC	16.613	Down-regulation
Other_IKK_IKBKB_ST	P01100	FOS	O14920	IKBKB	S364	S364I	364	Missense	central	0	yes	24.792	0.000	EPSD	COSMIC;GDSC;CCLE	16.613	Loss
Other_IKK_IKBKB_ST	P01100	FOS	O14920	IKBKB	S368	S371T	371	Missense	distal	3	no	20.545	19.551	EPSD	COSMIC	16.613	Down-regulation
Other_IKK_IKBKB_ST	P01100	FOS	O14920	IKBKB	S368	S364I	364	Missense	distal	-4	no	20.545	13.425	EPSD	COSMIC;GDSC;CCLE	16.613	Loss
Other_IKK_IKBKB_ST	P01100	FOS	O14920	IKBKB	S371	S364I	364	Missense	distal	-7	no	17.581	15.338	EPSD	COSMIC;GDSC;CCLE	16.613	Loss
Other_IKK_IKBKB_ST	P01100	FOS	O14920	IKBKB	S373	A379V	379	Missense	distal	6	no	16.606	17.401	EPSD	COSMIC	16.613	Gain
Other_IKK_IKBKB_ST	P01100	FOS	O14920	IKBKB	S374	S371T	371	Missense	distal	-3	no	18.156	18.235	EPSD	COSMIC	16.613	Up-regulation
Other_IKK_IKBKB_ST	P01100	FOS	O14920	IKBKB	S374	A379V	379	Missense	distal	5	no	18.156	16.434	EPSD	COSMIC	16.613	Loss
Other_IKK_IKBKB_ST	Q01201	RELB	O14920	IKBKB	S48	S50R	50	Missense	proximal	2	no	23.926	23.822	EPSD	COSMIC	16.613	Down-regulation
Other_IKK_IKBKB_ST	Q01201	RELB	O14920	IKBKB	S151	G150S	150	Missense	proximal	-1	no	19.299	18.909	EPSD	COSMIC	16.613	Down-regulation
Other_IKK_IKBKB_ST	Q01201	RELB	O14920	IKBKB	S151	R147H	147	Missense	distal	-4	no	19.299	19.602	EPSD	COSMIC;CCLE	16.613	Up-regulation
Other_IKK_IKBKB_ST	Q01201	RELB	O14920	IKBKB	S151	E145K	145	Missense	distal	-6	no	19.299	19.122	EPSD	COSMIC	16.613	Down-regulation
Other_IKK_IKBKB_ST	Q01201	RELB	O14920	IKBKB	S151	G154R	154	Missense	distal	3	no	19.299	19.191	EPSD	COSMIC;GDSC;CCLE	16.613	Down-regulation
Other_IKK_IKBKB_ST	Q01201	RELB	O14920	IKBKB	S151	E145Q	145	Missense	distal	-6	no	19.299	17.965	EPSD	COSMIC	16.613	Down-regulation
Other_IKK_IKBKB_ST	Q01201	RELB	O14920	IKBKB	S221	H215R	215	Missense	distal	-6	no	17.681	17.135	EPSD	COSMIC	16.613	Down-regulation
Other_IKK_IKBKB_ST	Q01201	RELB	O14920	IKBKB	S221	S221I	221	Missense	central	0	yes	17.681	0.000	EPSD	COSMIC	16.613	Loss
Other_IKK_IKBKB_ST	Q01201	RELB	O14920	IKBKB	S221	P214S	214	Missense	distal	-7	no	17.681	18.955	EPSD	COSMIC	16.613	Up-regulation
Other_IKK_IKBKB_ST	Q01201	RELB	O14920	IKBKB	S221	H220Y	220	Missense	proximal	-1	no	17.681	18.194	EPSD	COSMIC	16.613	Up-regulation
Other_IKK_IKBKB_ST	Q01201	RELB	O14920	IKBKB	S221	R219W	219	Missense	proximal	-2	no	17.681	18.362	EPSD	COSMIC	16.613	Up-regulation
Other_IKK_IKBKB_ST	Q92574	TSC1	O14920	IKBKB	S108	S108F	108	Missense	central	0	yes	21.638	0.000	EPSD	COSMIC	16.613	Loss
Other_IKK_IKBKB_ST	Q92574	TSC1	O14920	IKBKB	S108	S108P	108	Missense	central	0	yes	21.638	0.000	EPSD	COSMIC	16.613	Loss
Other_IKK_IKBKB_ST	Q92574	TSC1	O14920	IKBKB	S205	R204H	204	Missense	proximal	-1	no	23.388	23.301	EPSD	COSMIC;GDSC;CCLE	16.613	Down-regulation
Other_IKK_IKBKB_ST	Q92574	TSC1	O14920	IKBKB	S205	S205Y	205	Missense	central	0	yes	23.388	0.000	EPSD	COSMIC	16.613	Loss
Other_IKK_IKBKB_ST	Q92574	TSC1	O14920	IKBKB	S205	V200I	200	Missense	distal	-5	no	23.388	23.439	EPSD	COSMIC	16.613	Up-regulation
Other_IKK_IKBKB_ST	Q92574	TSC1	O14920	IKBKB	S205	R204L	204	Missense	proximal	-1	no	23.388	23.069	EPSD	COSMIC	16.613	Down-regulation
Other_IKK_IKBKB_ST	Q92574	TSC1	O14920	IKBKB	S205	H206P	206	Missense	proximal	1	no	23.388	23.467	EPSD	COSMIC	16.613	Up-regulation
Other_IKK_IKBKB_ST	Q92574	TSC1	O14920	IKBKB	S205	H206R	206	Missense	proximal	1	no	23.388	22.797	EPSD	COSMIC	16.613	Down-regulation
Other_IKK_IKBKB_ST	Q92574	TSC1	O14920	IKBKB	S205	R204S	204	Missense	proximal	-1	no	23.388	23.222	EPSD	COSMIC	16.613	Down-regulation
Other_IKK_IKBKB_ST	Q92574	TSC1	O14920	IKBKB	S205	K210E	210	Missense	distal	5	no	23.388	22.526	EPSD	COSMIC	16.613	Down-regulation
Other_IKK_IKBKB_ST	Q92574	TSC1	O14920	IKBKB	S276	H279Y	279	Missense	distal	3	no	18.671	17.859	EPSD	COSMIC	16.613	Down-regulation
Other_IKK_IKBKB_ST	Q92574	TSC1	O14920	IKBKB	S276	S278C	278	Missense	proximal	2	no	18.671	18.363	EPSD	COSMIC	16.613	Down-regulation
Other_IKK_IKBKB_ST	Q92574	TSC1	O14920	IKBKB	S276	Y275F	275	Missense	proximal	-1	no	18.671	18.535	EPSD	COSMIC	16.613	Down-regulation
Other_IKK_IKBKB_ST	Q92574	TSC1	O14920	IKBKB	S276	S276F	276	Missense	central	0	yes	18.671	0.000	EPSD	COSMIC	16.613	Loss
Other_IKK_IKBKB_ST	Q92574	TSC1	O14920	IKBKB	S276	S270P	270	Missense	distal	-6	no	18.671	18.411	EPSD	COSMIC	16.613	Down-regulation
Other_IKK_IKBKB_ST	Q92574	TSC1	O14920	IKBKB	S295	R288C	288	Missense	distal	-7	no	21.638	19.822	EPSD	COSMIC	16.613	Down-regulation
Other_IKK_IKBKB_ST	Q92574	TSC1	O14920	IKBKB	S427	K421E	421	Missense	distal	-6	no	17.786	17.963	EPSD	COSMIC	16.613	Up-regulation
Other_IKK_IKBKB_ST	Q92574	TSC1	O14920	IKBKB	S427	E422D	422	Missense	distal	-5	no	17.786	17.780	EPSD	COSMIC	16.613	Down-regulation
Other_IKK_IKBKB_ST	Q92574	TSC1	O14920	IKBKB	S427	E422V	422	Missense	distal	-5	no	17.786	17.444	EPSD	COSMIC	16.613	Down-regulation
Other_IKK_IKBKB_ST	Q92574	TSC1	O14920	IKBKB	S427	R424K	424	Missense	distal	-3	no	17.786	18.055	EPSD	COSMIC	16.613	Up-regulation
Other_IKK_IKBKB_ST	Q92574	TSC1	O14920	IKBKB	S427	D426Y	426	Missense	proximal	-1	no	17.786	18.076	EPSD	COSMIC	16.613	Up-regulation
Other_IKK_IKBKB_ST	Q92574	TSC1	O14920	IKBKB	S427	E423D	423	Missense	distal	-4	no	17.786	16.583	EPSD	COSMIC	16.613	Loss
Other_IKK_IKBKB_ST	Q92574	TSC1	O14920	IKBKB	S427	M425V	425	Missense	proximal	-2	no	17.786	17.482	EPSD	COSMIC	16.613	Down-regulation
Other_IKK_IKBKB_ST	Q92574	TSC1	O14920	IKBKB	S472	K477E	477	Missense	distal	5	no	24.119	23.257	EPSD	COSMIC	16.613	Down-regulation
Other_IKK_IKBKB_ST	Q92574	TSC1	O14920	IKBKB	S472	S468F	468	Missense	distal	-4	no	24.119	17.884	EPSD	COSMIC	16.613	Down-regulation
Other_IKK_IKBKB_ST	Q92574	TSC1	O14920	IKBKB	S472	S472N	472	Missense	central	0	yes	24.119	0.000	EPSD	COSMIC;GDSC;CCLE	16.613	Loss
Other_IKK_IKBKB_ST	Q92574	TSC1	O14920	IKBKB	S472	E478Q	478	Missense	distal	6	no	24.119	23.671	EPSD	COSMIC	16.613	Down-regulation
Other_IKK_IKBKB_ST	Q92574	TSC1	O14920	IKBKB	S483	K477E	477	Missense	distal	-6	no	22.413	22.589	EPSD	COSMIC	16.613	Up-regulation
Other_IKK_IKBKB_ST	Q92574	TSC1	O14920	IKBKB	S483	E478Q	478	Missense	distal	-5	no	22.413	21.912	EPSD	COSMIC	16.613	Down-regulation
Other_IKK_IKBKB_ST	Q92574	TSC1	O14920	IKBKB	S483	I482V	482	Missense	proximal	-1	no	22.413	22.049	EPSD	COSMIC	16.613	Down-regulation
Other_IKK_IKBKB_ST	Q92574	TSC1	O14920	IKBKB	S483	I482M	482	Missense	proximal	-1	no	22.413	21.632	EPSD	COSMIC	16.613	Down-regulation
Other_IKK_IKBKB_ST	Q92574	TSC1	O14920	IKBKB	S483	E485D	485	Missense	proximal	2	no	22.413	21.656	EPSD	COSMIC	16.613	Down-regulation
Other_IKK_IKBKB_ST	Q92574	TSC1	O14920	IKBKB	S483	E488V	488	Missense	distal	5	no	22.413	19.337	EPSD	COSMIC	16.613	Down-regulation
Other_IKK_IKBKB_ST	Q92574	TSC1	O14920	IKBKB	S483	S487C	487	Missense	distal	4	no	22.413	18.532	EPSD	COSMIC	16.613	Down-regulation
Other_IKK_IKBKB_ST	Q92574	TSC1	O14920	IKBKB	S487	I482V	482	Missense	distal	-5	no	18.619	18.567	PhosphoSitePlus;EPSD	COSMIC	16.613	Down-regulation
Other_IKK_IKBKB_ST	Q92574	TSC1	O14920	IKBKB	S487	I482M	482	Missense	distal	-5	no	18.619	19.014	PhosphoSitePlus;EPSD	COSMIC	16.613	Up-regulation
Other_IKK_IKBKB_ST	Q92574	TSC1	O14920	IKBKB	S487	E485D	485	Missense	proximal	-2	no	18.619	18.572	PhosphoSitePlus;EPSD	COSMIC	16.613	Down-regulation
Other_IKK_IKBKB_ST	Q92574	TSC1	O14920	IKBKB	S487	E488V	488	Missense	proximal	1	no	18.619	17.707	PhosphoSitePlus;EPSD	COSMIC	16.613	Down-regulation
Other_IKK_IKBKB_ST	Q92574	TSC1	O14920	IKBKB	S487	S487C	487	Missense	central	0	yes	18.619	0.000	PhosphoSitePlus;EPSD	COSMIC	16.613	Loss
Other_IKK_IKBKB_ST	Q92574	TSC1	O14920	IKBKB	S511	P506T	506	Missense	distal	-5	no	26.545	26.548	EPSD;PhosphoSitePlus	COSMIC	16.613	Up-regulation
Other_IKK_IKBKB_ST	Q92574	TSC1	O14920	IKBKB	S511	P506L	506	Missense	distal	-5	no	26.545	26.456	EPSD;PhosphoSitePlus	COSMIC	16.613	Down-regulation
Other_IKK_IKBKB_ST	Q92574	TSC1	O14920	IKBKB	S511	P513L	513	Missense	proximal	2	no	26.545	26.681	EPSD;PhosphoSitePlus	COSMIC	16.613	Up-regulation
Other_IKK_IKBKB_ST	Q92574	TSC1	O14920	IKBKB	S511	S505P	505	Missense	distal	-6	no	26.545	26.285	EPSD;PhosphoSitePlus	COSMIC	16.613	Down-regulation
Other_IKK_IKBKB_ST	Q92574	TSC1	O14920	IKBKB	S511	R517W	517	Missense	distal	6	no	26.545	27.838	EPSD;PhosphoSitePlus	COSMIC	16.613	Up-regulation
Other_IKK_IKBKB_ST	Q92574	TSC1	O14920	IKBKB	S521	S524F	524	Missense	distal	3	no	17.930	13.958	EPSD	COSMIC	16.613	Loss
Other_IKK_IKBKB_ST	Q92574	TSC1	O14920	IKBKB	S521	A522T	522	Missense	proximal	1	no	17.930	17.657	EPSD	COSMIC	16.613	Down-regulation
Other_IKK_IKBKB_ST	Q92574	TSC1	O14920	IKBKB	S521	Q527E	527	Missense	distal	6	no	17.930	18.379	EPSD	COSMIC	16.613	Up-regulation
Other_IKK_IKBKB_ST	Q92574	TSC1	O14920	IKBKB	S521	R517W	517	Missense	distal	-4	no	17.930	8.889	EPSD	COSMIC	16.613	Loss
Other_IKK_IKBKB_ST	Q92574	TSC1	O14920	IKBKB	S526	S524F	524	Missense	proximal	-2	no	19.060	19.798	EPSD	COSMIC	16.613	Up-regulation
Other_IKK_IKBKB_ST	Q92574	TSC1	O14920	IKBKB	S526	A522T	522	Missense	distal	-4	no	19.060	19.502	EPSD	COSMIC	16.613	Up-regulation
Other_IKK_IKBKB_ST	Q92574	TSC1	O14920	IKBKB	S526	Q527E	527	Missense	proximal	1	no	19.060	18.726	EPSD	COSMIC	16.613	Down-regulation
Other_IKK_IKBKB_ST	Q92574	TSC1	O14920	IKBKB	S530	S524F	524	Missense	distal	-6	no	19.116	17.968	EPSD	COSMIC	16.613	Down-regulation
Other_IKK_IKBKB_ST	Q92574	TSC1	O14920	IKBKB	S530	Q527E	527	Missense	distal	-3	no	19.116	19.236	EPSD	COSMIC	16.613	Up-regulation
Other_IKK_IKBKB_ST	Q92574	TSC1	O14920	IKBKB	S539	S538F	538	Missense	proximal	-1	no	16.590	17.045	EPSD	COSMIC	16.613	Gain
Other_IKK_IKBKB_ST	Q92574	TSC1	O14920	IKBKB	S539	K542T	542	Missense	distal	3	no	16.590	16.865	EPSD	COSMIC	16.613	Gain
Other_IKK_IKBKB_ST	Q92574	TSC1	O14920	IKBKB	S539	K542E	542	Missense	distal	3	no	16.590	17.618	EPSD	COSMIC	16.613	Gain
Other_IKK_IKBKB_ST	Q92574	TSC1	O14920	IKBKB	S565	C572Y	572	Missense	distal	7	no	17.020	16.623	EPSD	COSMIC;GDSC;CCLE	16.613	Down-regulation
Other_IKK_IKBKB_ST	Q92574	TSC1	O14920	IKBKB	S565	G560S	560	Missense	distal	-5	no	17.020	17.148	EPSD	COSMIC	16.613	Up-regulation
Other_IKK_IKBKB_ST	Q92574	TSC1	O14920	IKBKB	S565	P566H	566	Missense	proximal	1	no	17.020	16.941	EPSD	COSMIC	16.613	Down-regulation
Other_IKK_IKBKB_ST	Q92574	TSC1	O14920	IKBKB	S565	A567V	567	Missense	proximal	2	no	17.020	17.016	EPSD	COSMIC	16.613	Down-regulation
Other_IKK_IKBKB_ST	Q92574	TSC1	O14920	IKBKB	S565	E564K	564	Missense	proximal	-1	no	17.020	16.960	EPSD	COSMIC	16.613	Down-regulation
Other_IKK_IKBKB_ST	Q92574	TSC1	O14920	IKBKB	S575	L576R	576	Missense	proximal	1	no	26.423	26.045	EPSD	COSMIC	16.613	Down-regulation
Other_IKK_IKBKB_ST	Q92574	TSC1	O14920	IKBKB	S575	C572Y	572	Missense	distal	-3	no	26.423	26.269	EPSD	COSMIC;GDSC;CCLE	16.613	Down-regulation
Other_IKK_IKBKB_ST	Q92574	TSC1	O14920	IKBKB	S575	E577K	577	Missense	proximal	2	no	26.423	26.545	EPSD	COSMIC	16.613	Up-regulation
Other_IKK_IKBKB_ST	Q92574	TSC1	O14920	IKBKB	S575	Q573E	573	Missense	proximal	-2	no	26.423	25.885	EPSD	COSMIC	16.613	Down-regulation
Other_IKK_IKBKB_ST	Q92574	TSC1	O14920	IKBKB	S575	E577D	577	Missense	proximal	2	no	26.423	25.666	EPSD	COSMIC	16.613	Down-regulation
Other_IKK_IKBKB_ST	Q92574	TSC1	O14920	IKBKB	S579	L576R	576	Missense	distal	-3	no	19.544	20.112	EPSD	COSMIC	16.613	Up-regulation
Other_IKK_IKBKB_ST	Q92574	TSC1	O14920	IKBKB	S579	C572Y	572	Missense	distal	-7	no	19.544	18.418	EPSD	COSMIC;GDSC;CCLE	16.613	Down-regulation
Other_IKK_IKBKB_ST	Q92574	TSC1	O14920	IKBKB	S579	P585A	585	Missense	distal	6	no	19.544	19.434	EPSD	COSMIC	16.613	Down-regulation
Other_IKK_IKBKB_ST	Q92574	TSC1	O14920	IKBKB	S579	E577K	577	Missense	proximal	-2	no	19.544	19.309	EPSD	COSMIC	16.613	Down-regulation
Other_IKK_IKBKB_ST	Q92574	TSC1	O14920	IKBKB	S579	Q573E	573	Missense	distal	-6	no	19.544	20.877	EPSD	COSMIC	16.613	Up-regulation
Other_IKK_IKBKB_ST	Q92574	TSC1	O14920	IKBKB	S579	P583S	583	Missense	distal	4	no	19.544	21.743	EPSD	COSMIC	16.613	Up-regulation
Other_IKK_IKBKB_ST	Q92574	TSC1	O14920	IKBKB	S579	E577D	577	Missense	proximal	-2	no	19.544	19.497	EPSD	COSMIC	16.613	Down-regulation
Other_IKK_IKBKB_ST	Q92574	TSC1	O14920	IKBKB	S644	V648M	648	Missense	distal	4	no	9.230	16.803	EPSD	COSMIC	16.613	Gain
Other_IKK_IKBKB_ST	Q92574	TSC1	O14920	IKBKB	S871	H870R	870	Missense	proximal	-1	no	20.352	20.439	EPSD	COSMIC	16.613	Up-regulation
Other_IKK_IKBKB_ST	Q92574	TSC1	O14920	IKBKB	S871	H870Y	870	Missense	proximal	-1	no	20.352	20.864	EPSD	COSMIC	16.613	Up-regulation
Other_IKK_IKBKB_ST	Q92574	TSC1	O14920	IKBKB	S871	E878K	878	Missense	distal	7	no	20.352	20.055	EPSD	COSMIC	16.613	Down-regulation
Other_IKK_IKBKB_ST	Q92574	TSC1	O14920	IKBKB	S1029	G1034S	1034	Missense	distal	5	no	13.842	17.154	EPSD	COSMIC	16.613	Gain
Other_IKK_IKBKB_ST	Q92574	TSC1	O14920	IKBKB	S1038	S1038G	1038	Missense	central	0	yes	20.599	0.000	EPSD	COSMIC	16.613	Loss
Other_IKK_IKBKB_ST	Q92574	TSC1	O14920	IKBKB	S1038	S1042N	1042	Missense	distal	4	no	20.599	17.732	EPSD	COSMIC	16.613	Down-regulation
Other_IKK_IKBKB_ST	Q92574	TSC1	O14920	IKBKB	S1038	G1034S	1034	Missense	distal	-4	no	20.599	26.874	EPSD	COSMIC	16.613	Up-regulation
Other_IKK_IKBKB_ST	Q92574	TSC1	O14920	IKBKB	S1038	G1036S	1036	Missense	proximal	-2	no	20.599	19.886	EPSD	COSMIC	16.613	Down-regulation
Other_IKK_IKBKB_ST	Q92574	TSC1	O14920	IKBKB	S1038	G1034C	1034	Missense	distal	-4	no	20.599	21.176	EPSD	COSMIC;GDSC;CCLE	16.613	Up-regulation
Other_IKK_IKBKB_ST	Q92574	TSC1	O14920	IKBKB	S1038	G1037S	1037	Missense	proximal	-1	no	20.599	20.209	EPSD	COSMIC	16.613	Down-regulation
Other_IKK_IKBKB_ST	Q92574	TSC1	O14920	IKBKB	S1038	G1031S	1031	Missense	distal	-7	no	20.599	20.377	EPSD	COSMIC	16.613	Down-regulation
Other_IKK_IKBKB_ST	Q92574	TSC1	O14920	IKBKB	S1038	G1035S	1035	Missense	distal	-3	no	20.599	20.866	EPSD	COSMIC	16.613	Up-regulation
Other_IKK_IKBKB_ST	Q92574	TSC1	O14920	IKBKB	S1038	S1032R	1032	Missense	distal	-6	no	20.599	19.941	EPSD	COSMIC	16.613	Down-regulation
Other_IKK_IKBKB_ST	Q92574	TSC1	O14920	IKBKB	S1038	S1038N	1038	Missense	central	0	yes	20.599	0.000	EPSD	COSMIC	16.613	Loss
Other_IKK_IKBKB_ST	Q92574	TSC1	O14920	IKBKB	S1039	S1038G	1038	Missense	proximal	-1	no	22.000	22.390	EPSD	COSMIC	16.613	Up-regulation
Other_IKK_IKBKB_ST	Q92574	TSC1	O14920	IKBKB	S1039	S1042N	1042	Missense	distal	3	no	22.000	21.225	EPSD	COSMIC	16.613	Down-regulation
Other_IKK_IKBKB_ST	Q92574	TSC1	O14920	IKBKB	S1039	G1034S	1034	Missense	distal	-5	no	22.000	22.128	EPSD	COSMIC	16.613	Up-regulation
Other_IKK_IKBKB_ST	Q92574	TSC1	O14920	IKBKB	S1039	G1036S	1036	Missense	distal	-3	no	22.000	22.266	EPSD	COSMIC	16.613	Up-regulation
Other_IKK_IKBKB_ST	Q92574	TSC1	O14920	IKBKB	S1039	G1034C	1034	Missense	distal	-5	no	22.000	21.886	EPSD	COSMIC;GDSC;CCLE	16.613	Down-regulation
Other_IKK_IKBKB_ST	Q92574	TSC1	O14920	IKBKB	S1039	G1037S	1037	Missense	proximal	-2	no	22.000	21.286	EPSD	COSMIC	16.613	Down-regulation
Other_IKK_IKBKB_ST	Q92574	TSC1	O14920	IKBKB	S1039	G1035S	1035	Missense	distal	-4	no	22.000	28.275	EPSD	COSMIC	16.613	Up-regulation
Other_IKK_IKBKB_ST	Q92574	TSC1	O14920	IKBKB	S1039	S1032R	1032	Missense	distal	-7	no	22.000	22.469	EPSD	COSMIC	16.613	Up-regulation
Other_IKK_IKBKB_ST	Q92574	TSC1	O14920	IKBKB	S1039	S1038N	1038	Missense	proximal	-1	no	22.000	21.855	EPSD	COSMIC	16.613	Down-regulation
Other_IKK_IKBKB_ST	Q92574	TSC1	O14920	IKBKB	S1039	S1046C	1046	Missense	distal	7	no	22.000	21.110	EPSD	COSMIC	16.613	Down-regulation
Other_IKK_IKBKB_ST	Q92574	TSC1	O14920	IKBKB	S1041	G1037S	1037	Missense	distal	-4	no	10.450	16.726	EPSD	COSMIC	16.613	Gain
Other_IKK_IKBKB_ST	Q92574	TSC1	O14920	IKBKB	S1042	G1036S	1036	Missense	distal	-6	no	16.084	16.781	EPSD	COSMIC	16.613	Gain
Other_IKK_IKBKB_ST	Q92574	TSC1	O14920	IKBKB	S1046	P1051Q	1051	Missense	distal	5	no	24.987	25.810	EPSD	COSMIC	16.613	Up-regulation
Other_IKK_IKBKB_ST	Q92574	TSC1	O14920	IKBKB	S1046	S1042N	1042	Missense	distal	-4	no	24.987	21.282	EPSD	COSMIC	16.613	Down-regulation
Other_IKK_IKBKB_ST	Q92574	TSC1	O14920	IKBKB	S1046	P1051S	1051	Missense	distal	5	no	24.987	25.187	EPSD	COSMIC	16.613	Up-regulation
Other_IKK_IKBKB_ST	Q92574	TSC1	O14920	IKBKB	S1046	T1047I	1047	Missense	proximal	1	no	24.987	27.851	EPSD	COSMIC;CCLE	16.613	Up-regulation
Other_IKK_IKBKB_ST	Q92574	TSC1	O14920	IKBKB	S1046	P1052Q	1052	Missense	distal	6	no	24.987	24.638	EPSD	COSMIC	16.613	Down-regulation
Other_IKK_IKBKB_ST	Q92574	TSC1	O14920	IKBKB	S1046	P1052S	1052	Missense	distal	6	no	24.987	23.663	EPSD	COSMIC	16.613	Down-regulation
Other_IKK_IKBKB_ST	Q92574	TSC1	O14920	IKBKB	S1046	S1046C	1046	Missense	central	0	yes	24.987	0.000	EPSD	COSMIC	16.613	Loss
Other_IKK_IKBKB_ST	Q92574	TSC1	O14920	IKBKB	S1073	E1069D	1069	Missense	distal	-4	no	22.822	21.619	EPSD	COSMIC	16.613	Down-regulation
Other_IKK_IKBKB_ST	Q92574	TSC1	O14920	IKBKB	S1073	A1070T	1070	Missense	distal	-3	no	22.822	22.770	EPSD	COSMIC	16.613	Down-regulation
Other_IKK_IKBKB_ST	Q92574	TSC1	O14920	IKBKB	S1073	A1072T	1072	Missense	proximal	-1	no	22.822	22.949	EPSD	COSMIC	16.613	Up-regulation
Other_IKK_IKBKB_ST	Q92574	TSC1	O14920	IKBKB	S1080	K1085T	1085	Missense	distal	5	no	21.410	18.156	EPSD	COSMIC	16.613	Down-regulation
Other_IKK_IKBKB_ST	Q92574	TSC1	O14920	IKBKB	S1086	K1091T	1091	Missense	distal	5	no	23.489	20.235	EPSD	COSMIC	16.613	Down-regulation
Other_IKK_IKBKB_ST	Q92574	TSC1	O14920	IKBKB	S1086	K1085T	1085	Missense	proximal	-1	no	23.489	23.550	EPSD	COSMIC	16.613	Up-regulation
Other_IKK_IKBKB_ST	Q92574	TSC1	O14920	IKBKB	S1086	L1088V	1088	Missense	proximal	2	no	23.489	23.891	EPSD	COSMIC	16.613	Up-regulation
Other_IKK_IKBKB_ST	Q92574	TSC1	O14920	IKBKB	S1111	E1106K	1106	Missense	distal	-5	no	16.869	16.874	EPSD	COSMIC	16.613	Up-regulation
Other_IKK_IKBKB_ST	Q92574	TSC1	O14920	IKBKB	S1111	E1115K	1115	Missense	distal	4	no	16.869	14.010	EPSD	COSMIC	16.613	Loss
Other_IKK_IKBKB_ST	Q92574	TSC1	O14920	IKBKB	S1111	G1108S	1108	Missense	distal	-3	no	16.869	17.135	EPSD	COSMIC	16.613	Up-regulation
Other_IKK_IKBKB_ST	Q92574	TSC1	O14920	IKBKB	S1111	E1115D	1115	Missense	distal	4	no	16.869	12.082	EPSD	COSMIC	16.613	Loss
Other_IKK_IKBKB_ST	Q92574	TSC1	O14920	IKBKB	S1112	G1108S	1108	Missense	distal	-4	no	12.763	19.039	EPSD	COSMIC	16.613	Gain
Other_IKK_IKBKB_ST	Q92574	TSC1	O14920	IKBKB	S1116	E1120D	1120	Missense	distal	4	no	23.988	19.201	EPSD	COSMIC	16.613	Down-regulation
Other_IKK_IKBKB_ST	Q92574	TSC1	O14920	IKBKB	S1116	E1115K	1115	Missense	proximal	-1	no	23.988	23.928	EPSD	COSMIC	16.613	Down-regulation
Other_IKK_IKBKB_ST	Q92574	TSC1	O14920	IKBKB	S1116	E1115D	1115	Missense	proximal	-1	no	23.988	24.321	EPSD	COSMIC	16.613	Up-regulation
Other_IKK_IKBKB_ST	Q92574	TSC1	O14920	IKBKB	S1141	G1137S	1137	Missense	distal	-4	no	12.000	18.275	EPSD	COSMIC	16.613	Gain
Other_IKK_IKBKB_ST	Q92574	TSC1	O14920	IKBKB	S1147	P1142L	1142	Missense	distal	-5	no	19.020	18.931	EPSD	COSMIC	16.613	Down-regulation
Other_IKK_IKBKB_ST	Q92574	TSC1	O14920	IKBKB	S1147	M1154I	1154	Missense	distal	7	no	19.020	17.610	EPSD	COSMIC	16.613	Down-regulation
Other_IKK_IKBKB_ST	O95999	BCL10	O14920	IKBKB	S121	S120I	120	Missense	proximal	-1	no	16.148	16.773	EPSD	COSMIC	16.613	Gain
Other_IKK_IKBKB_ST	O95999	BCL10	O14920	IKBKB	S141	R148S	148	Missense	distal	7	no	25.356	25.745	EPSD;PhosphoSitePlus	COSMIC	16.613	Up-regulation
Other_IKK_IKBKB_ST	O95999	BCL10	O14920	IKBKB	S144	R148S	148	Missense	distal	4	no	16.566	19.131	EPSD;PhosphoSitePlus	COSMIC	16.613	Gain
Other_IKK_IKBKB_ST	O95999	BCL10	O14920	IKBKB	S144	T151M	151	Missense	distal	7	no	16.566	17.640	EPSD;PhosphoSitePlus	COSMIC	16.613	Gain
Other_IKK_IKBKB_ST	O95999	BCL10	O14920	IKBKB	S167	S160F	160	Missense	distal	-7	no	16.643	14.461	EPSD	COSMIC	16.613	Loss
Other_IKK_IKBKB_ST	O95999	BCL10	O14920	IKBKB	S167	T163M	163	Missense	distal	-4	no	16.643	20.869	EPSD	COSMIC	16.613	Up-regulation
Other_IKK_IKBKB_ST	O95999	BCL10	O14920	IKBKB	S167	P164H	164	Missense	distal	-3	no	16.643	17.056	EPSD	COSMIC	16.613	Up-regulation
Other_IKK_IKBKB_ST	O95999	BCL10	O14920	IKBKB	S167	S170Y	170	Missense	distal	3	no	16.643	14.610	EPSD	COSMIC	16.613	Loss
Other_IKK_IKBKB_ST	O95999	BCL10	O14920	IKBKB	S167	S167P	167	Missense	central	0	yes	16.643	0.000	EPSD	COSMIC	16.613	Loss
Other_IKK_IKBKB_ST	O95999	BCL10	O14920	IKBKB	S167	S170C	170	Missense	distal	3	no	16.643	13.662	EPSD	COSMIC	16.613	Loss
Other_IKK_IKBKB_ST	O95999	BCL10	O14920	IKBKB	S167	T163P	163	Missense	distal	-4	no	16.643	16.820	EPSD	COSMIC	16.613	Up-regulation
Other_IKK_IKBKB_ST	O95999	BCL10	O14920	IKBKB	S167	N169Y	169	Missense	proximal	2	no	16.643	15.935	EPSD	COSMIC	16.613	Loss
Other_IKK_IKBKB_ST	O95999	BCL10	O14920	IKBKB	S167	S160T	160	Missense	distal	-7	no	16.643	17.009	EPSD	COSMIC	16.613	Up-regulation
Other_IKK_IKBKB_ST	O95999	BCL10	O14920	IKBKB	S170	T163M	163	Missense	distal	-7	no	16.668	17.366	EPSD	COSMIC	16.613	Up-regulation
Other_IKK_IKBKB_ST	O95999	BCL10	O14920	IKBKB	S170	P164H	164	Missense	distal	-6	no	16.668	16.816	EPSD	COSMIC	16.613	Up-regulation
Other_IKK_IKBKB_ST	O95999	BCL10	O14920	IKBKB	S170	S170Y	170	Missense	central	0	yes	16.668	0.000	EPSD	COSMIC	16.613	Loss
Other_IKK_IKBKB_ST	O95999	BCL10	O14920	IKBKB	S170	S167P	167	Missense	distal	-3	no	16.668	16.121	EPSD	COSMIC	16.613	Loss
Other_IKK_IKBKB_ST	O95999	BCL10	O14920	IKBKB	S170	S170C	170	Missense	central	0	yes	16.668	0.000	EPSD	COSMIC	16.613	Loss
Other_IKK_IKBKB_ST	O95999	BCL10	O14920	IKBKB	S170	T163P	163	Missense	distal	-7	no	16.668	15.028	EPSD	COSMIC	16.613	Loss
Other_IKK_IKBKB_ST	O95999	BCL10	O14920	IKBKB	S170	N169Y	169	Missense	proximal	-1	no	16.668	17.404	EPSD	COSMIC	16.613	Up-regulation
Other_IKK_IKBKB_ST	O95999	BCL10	O14920	IKBKB	S218	L225F	225	Missense	distal	7	no	19.414	18.910	EPSD	COSMIC	16.613	Down-regulation
Other_IKK_IKBKB_ST	O95999	BCL10	O14920	IKBKB	S218	G213R	213	Missense	distal	-5	no	19.414	19.512	EPSD	COSMIC	16.613	Up-regulation
Other_IKK_IKBKB_ST	O95999	BCL10	O14920	IKBKB	S218	P224S	224	Missense	distal	6	no	19.414	18.089	EPSD	COSMIC	16.613	Down-regulation
Other_IKK_IKBKB_ST	P42858	HTT	O14920	IKBKB	S415	R416H	416	Missense	proximal	1	no	25.554	26.145	EPSD	COSMIC	16.613	Up-regulation
Other_IKK_IKBKB_ST	P42858	HTT	O14920	IKBKB	S415	E409K	409	Missense	distal	-6	no	25.554	25.378	EPSD	COSMIC	16.613	Down-regulation
Other_IKK_IKBKB_ST	P42858	HTT	O14920	IKBKB	S419	R416H	416	Missense	distal	-3	no	17.051	16.758	EPSD	COSMIC	16.613	Down-regulation
Other_IKK_IKBKB_ST	P42858	HTT	O14920	IKBKB	S459	V461A	461	Missense	proximal	2	no	21.565	21.568	EPSD	COSMIC	16.613	Up-regulation
Other_IKK_IKBKB_ST	P42858	HTT	O14920	IKBKB	S459	R458T	458	Missense	proximal	-1	no	21.565	21.368	EPSD	COSMIC;GDSC;CCLE	16.613	Down-regulation
Other_IKK_IKBKB_ST	P42858	HTT	O14920	IKBKB	S1111	L1105P	1105	Missense	distal	-6	no	20.466	20.841	EPSD	COSMIC	16.613	Up-regulation
Other_IKK_IKBKB_ST	P42858	HTT	O14920	IKBKB	S1111	P1117S	1117	Missense	distal	6	no	20.466	19.142	EPSD	COSMIC	16.613	Down-regulation
Other_IKK_IKBKB_ST	P42858	HTT	O14920	IKBKB	S1111	A1115G	1115	Missense	distal	4	no	20.466	18.117	EPSD	COSMIC	16.613	Down-regulation
Other_IKK_IKBKB_ST	P42858	HTT	O14920	IKBKB	S1171	T1173A	1173	Missense	proximal	2	no	16.552	16.716	EPSD	COSMIC	16.613	Gain
Other_IKK_IKBKB_ST	P42858	HTT	O14920	IKBKB	S1179	L1178P	1178	Missense	proximal	-1	no	17.540	17.696	EPSD	COSMIC	16.613	Up-regulation
Other_IKK_IKBKB_ST	P42858	HTT	O14920	IKBKB	S1179	T1173A	1173	Missense	distal	-6	no	17.540	17.686	EPSD	COSMIC	16.613	Up-regulation
Other_IKK_IKBKB_ST	P42858	HTT	O14920	IKBKB	S1179	K1186N	1186	Missense	distal	7	no	17.540	16.754	EPSD	COSMIC	16.613	Down-regulation
Other_IKK_IKBKB_ST	P42858	HTT	O14920	IKBKB	S1199	S1199C	1199	Missense	central	0	yes	18.582	0.000	EPSD	COSMIC	16.613	Loss
Other_IKK_IKBKB_ST	P42858	HTT	O14920	IKBKB	S1199	A1206V	1206	Missense	distal	7	no	18.582	17.394	EPSD	COSMIC	16.613	Down-regulation
Other_IKK_IKBKB_ST	P42858	HTT	O14920	IKBKB	S1199	E1192K	1192	Missense	distal	-7	no	18.582	18.027	EPSD	COSMIC	16.613	Down-regulation
Other_IKK_IKBKB_ST	P42858	HTT	O14920	IKBKB	S1229	Y1231C	1231	Missense	proximal	2	no	16.875	17.309	EPSD	COSMIC	16.613	Up-regulation
Other_IKK_IKBKB_ST	P42858	HTT	O14920	IKBKB	S1862	S1862N	1862	Missense	central	0	yes	17.613	0.000	EPSD	COSMIC	16.613	Loss
Other_IKK_IKBKB_ST	P42858	HTT	O14920	IKBKB	S1864	S1862N	1862	Missense	proximal	-2	no	20.005	19.922	EPSD	COSMIC	16.613	Down-regulation
Other_IKK_IKBKB_ST	P42858	HTT	O14920	IKBKB	S1865	S1862N	1862	Missense	distal	-3	no	16.705	17.082	EPSD	COSMIC	16.613	Up-regulation
Other_IKK_IKBKB_ST	P42858	HTT	O14920	IKBKB	S2074	P2081L	2081	Missense	distal	7	no	18.883	19.084	EPSD	COSMIC;GDSC	16.613	Up-regulation
Other_IKK_IKBKB_ST	P42858	HTT	O14920	IKBKB	S2074	H2080P	2080	Missense	distal	6	no	18.883	19.574	EPSD	COSMIC	16.613	Up-regulation
Other_IKK_IKBKB_ST	P42858	HTT	O14920	IKBKB	S2138	N2141D	2141	Missense	distal	3	no	18.188	18.091	EPSD	COSMIC	16.613	Down-regulation
Other_IKK_IKBKB_ST	P42858	HTT	O14920	IKBKB	S2138	S2143N	2143	Missense	distal	5	no	18.188	16.735	EPSD	COSMIC	16.613	Down-regulation
Other_IKK_IKBKB_ST	P42858	HTT	O14920	IKBKB	S2138	L2144R	2144	Missense	distal	6	no	18.188	17.605	EPSD	COSMIC	16.613	Down-regulation
Other_IKK_IKBKB_ST	P42858	HTT	O14920	IKBKB	S2138	M2131V	2131	Missense	distal	-7	no	18.188	14.790	EPSD	COSMIC;GDSC;CCLE	16.613	Loss
Other_IKK_IKBKB_ST	P42858	HTT	O14920	IKBKB	S2143	P2147S	2147	Missense	distal	4	no	15.155	17.355	EPSD	COSMIC;GDSC;CCLE	16.613	Gain
Other_IKK_IKBKB_ST	P42858	HTT	O14920	IKBKB	S2651	D2645N	2645	Missense	distal	-6	no	16.872	17.220	EPSD	COSMIC	16.613	Up-regulation
Other_IKK_IKBKB_ST	P42858	HTT	O14920	IKBKB	S2764	R2765H	2765	Missense	proximal	1	no	16.973	17.564	EPSD	COSMIC	16.613	Up-regulation
Other_IKK_IKBKB_ST	P42858	HTT	O14920	IKBKB	S2764	P2762S	2762	Missense	proximal	-2	no	16.973	16.087	EPSD	COSMIC;GDSC;CCLE	16.613	Loss
Other_IKK_IKBKB_ST	P42858	HTT	O14920	IKBKB	S2764	V2759M	2759	Missense	distal	-5	no	16.973	17.420	EPSD	COSMIC	16.613	Up-regulation
Other_IKK_IKBKB_ST	P19438	TNFRSF1A	O14920	IKBKB	S381	V375M	375	Missense	distal	-6	no	17.341	19.333	PhosphoSitePlus	COSMIC	16.613	Up-regulation
Other_IKK_IKBKB_ST	P19438	TNFRSF1A	O14920	IKBKB	S381	R376Q	376	Missense	distal	-5	no	17.341	16.833	PhosphoSitePlus	COSMIC	16.613	Down-regulation
Other_IKK_IKBKB_ST	P19438	TNFRSF1A	O14920	IKBKB	S381	R387W	387	Missense	distal	6	no	17.341	18.634	PhosphoSitePlus	COSMIC	16.613	Up-regulation
Other_IKK_IKBKB_ST	P19438	TNFRSF1A	O14920	IKBKB	S402	E398K	398	Missense	distal	-4	no	17.485	15.027	EPSD	COSMIC	16.613	Loss
Other_IKK_IKBKB_ST	P19438	TNFRSF1A	O14920	IKBKB	S402	R397C	397	Missense	distal	-5	no	17.485	17.273	EPSD	COSMIC;CCLE	16.613	Down-regulation
Other_IKK_IKBKB_ST	P19438	TNFRSF1A	O14920	IKBKB	S402	R408W	408	Missense	distal	6	no	17.485	18.778	EPSD	COSMIC;CCLE	16.613	Up-regulation
Other_IKK_IKBKB_ST	Q6P2E9	EDC4	O14920	IKBKB	S55	D57H	57	Missense	proximal	2	no	25.388	25.366	EPSD	COSMIC	16.613	Down-regulation
Other_IKK_IKBKB_ST	Q6P2E9	EDC4	O14920	IKBKB	S55	P50S	50	Missense	distal	-5	no	25.388	25.355	EPSD	COSMIC	16.613	Down-regulation
Other_IKK_IKBKB_ST	Q6P2E9	EDC4	O14920	IKBKB	S103	V98M	98	Missense	distal	-5	no	16.885	17.332	EPSD	COSMIC	16.613	Up-regulation
Other_IKK_IKBKB_ST	Q6P2E9	EDC4	O14920	IKBKB	S103	S103C	103	Missense	central	0	yes	16.885	0.000	EPSD	COSMIC	16.613	Loss
Other_IKK_IKBKB_ST	Q6P2E9	EDC4	O14920	IKBKB	S106	S103C	103	Missense	distal	-3	no	18.656	18.236	EPSD	COSMIC	16.613	Down-regulation
Other_IKK_IKBKB_ST	Q6P2E9	EDC4	O14920	IKBKB	S106	R113Q	113	Missense	distal	7	no	18.656	18.824	EPSD	COSMIC	16.613	Up-regulation
Other_IKK_IKBKB_ST	Q6P2E9	EDC4	O14920	IKBKB	S107	S103C	103	Missense	distal	-4	no	18.539	12.841	EPSD;PhosphoSitePlus	COSMIC	16.613	Loss
Other_IKK_IKBKB_ST	Q6P2E9	EDC4	O14920	IKBKB	S107	R113Q	113	Missense	distal	6	no	18.539	18.891	EPSD;PhosphoSitePlus	COSMIC	16.613	Up-regulation
Other_IKK_IKBKB_ST	Q6P2E9	EDC4	O14920	IKBKB	S613	Q607E	607	Missense	distal	-6	no	21.529	22.863	EPSD	COSMIC	16.613	Up-regulation
Other_IKK_IKBKB_ST	Q6P2E9	EDC4	O14920	IKBKB	S613	S611F	611	Missense	proximal	-2	no	21.529	22.267	EPSD	COSMIC	16.613	Up-regulation
Other_IKK_IKBKB_ST	Q6P2E9	EDC4	O14920	IKBKB	S621	S621N	621	Missense	central	0	yes	23.268	0.000	EPSD	COSMIC	16.613	Loss
Other_IKK_IKBKB_ST	Q6P2E9	EDC4	O14920	IKBKB	S621	S627N	627	Missense	distal	6	no	23.268	24.675	EPSD	COSMIC	16.613	Up-regulation
Other_IKK_IKBKB_ST	Q6P2E9	EDC4	O14920	IKBKB	S621	S624N	624	Missense	distal	3	no	23.268	22.493	EPSD	COSMIC;CCLE	16.613	Down-regulation
Other_IKK_IKBKB_ST	Q6P2E9	EDC4	O14920	IKBKB	S621	S628R	628	Missense	distal	7	no	23.268	22.879	EPSD	COSMIC	16.613	Down-regulation
Other_IKK_IKBKB_ST	Q6P2E9	EDC4	O14920	IKBKB	S622	S621N	621	Missense	proximal	-1	no	20.619	20.475	EPSD	COSMIC	16.613	Down-regulation
Other_IKK_IKBKB_ST	Q6P2E9	EDC4	O14920	IKBKB	S622	S627N	627	Missense	distal	5	no	20.619	19.165	EPSD	COSMIC	16.613	Down-regulation
Other_IKK_IKBKB_ST	Q6P2E9	EDC4	O14920	IKBKB	S622	S624N	624	Missense	proximal	2	no	20.619	20.585	EPSD	COSMIC;CCLE	16.613	Down-regulation
Other_IKK_IKBKB_ST	Q6P2E9	EDC4	O14920	IKBKB	S622	S628R	628	Missense	distal	6	no	20.619	21.243	EPSD	COSMIC	16.613	Up-regulation
Other_IKK_IKBKB_ST	Q6P2E9	EDC4	O14920	IKBKB	S623	S621N	621	Missense	proximal	-2	no	24.194	24.111	EPSD	COSMIC	16.613	Down-regulation
Other_IKK_IKBKB_ST	Q6P2E9	EDC4	O14920	IKBKB	S623	S627N	627	Missense	distal	4	no	24.194	21.327	EPSD	COSMIC	16.613	Down-regulation
Other_IKK_IKBKB_ST	Q6P2E9	EDC4	O14920	IKBKB	S623	S624N	624	Missense	proximal	1	no	24.194	24.909	EPSD	COSMIC;CCLE	16.613	Up-regulation
Other_IKK_IKBKB_ST	Q6P2E9	EDC4	O14920	IKBKB	S623	S628R	628	Missense	distal	5	no	24.194	23.096	EPSD	COSMIC	16.613	Down-regulation
Other_IKK_IKBKB_ST	Q6P2E9	EDC4	O14920	IKBKB	S624	S621N	621	Missense	distal	-3	no	19.488	19.865	EPSD	COSMIC	16.613	Up-regulation
Other_IKK_IKBKB_ST	Q6P2E9	EDC4	O14920	IKBKB	S624	S627N	627	Missense	distal	3	no	19.488	18.714	EPSD	COSMIC	16.613	Down-regulation
Other_IKK_IKBKB_ST	Q6P2E9	EDC4	O14920	IKBKB	S624	S624N	624	Missense	central	0	yes	19.488	0.000	EPSD	COSMIC;CCLE	16.613	Loss
Other_IKK_IKBKB_ST	Q6P2E9	EDC4	O14920	IKBKB	S624	S628R	628	Missense	distal	4	no	19.488	16.923	EPSD	COSMIC	16.613	Down-regulation
Other_IKK_IKBKB_ST	Q6P2E9	EDC4	O14920	IKBKB	S664	T666A	666	Missense	proximal	2	no	17.590	17.754	EPSD	COSMIC	16.613	Up-regulation
Other_IKK_IKBKB_ST	Q6P2E9	EDC4	O14920	IKBKB	S670	T666A	666	Missense	distal	-4	no	23.996	23.555	EPSD	COSMIC	16.613	Down-regulation
Other_IKK_IKBKB_ST	Q6P2E9	EDC4	O14920	IKBKB	S672	T666A	666	Missense	distal	-6	no	18.921	19.066	EPSD	COSMIC	16.613	Up-regulation
Other_IKK_IKBKB_ST	Q6P2E9	EDC4	O14920	IKBKB	S672	R678H	678	Missense	distal	6	no	18.921	18.931	EPSD	COSMIC	16.613	Up-regulation
Other_IKK_IKBKB_ST	Q6P2E9	EDC4	O14920	IKBKB	S676	R678H	678	Missense	proximal	2	no	19.512	19.490	EPSD	COSMIC	16.613	Down-regulation
Other_IKK_IKBKB_ST	Q6P2E9	EDC4	O14920	IKBKB	S734	R728C	728	Missense	distal	-6	no	18.167	17.638	EPSD	COSMIC	16.613	Down-regulation
Other_IKK_IKBKB_ST	Q6P2E9	EDC4	O14920	IKBKB	S734	R728H	728	Missense	distal	-6	no	18.167	18.713	EPSD	COSMIC	16.613	Up-regulation
Other_IKK_IKBKB_ST	Q6P2E9	EDC4	O14920	IKBKB	S735	R728C	728	Missense	distal	-7	no	18.217	16.401	EPSD	COSMIC	16.613	Loss
Other_IKK_IKBKB_ST	Q6P2E9	EDC4	O14920	IKBKB	S735	R728H	728	Missense	distal	-7	no	18.217	17.023	EPSD	COSMIC	16.613	Down-regulation
Other_IKK_IKBKB_ST	Q6P2E9	EDC4	O14920	IKBKB	S771	E765Q	765	Missense	distal	-6	no	18.572	17.238	EPSD	COSMIC	16.613	Down-regulation
Other_IKK_IKBKB_ST	Q6P2E9	EDC4	O14920	IKBKB	S771	A775G	775	Missense	distal	4	no	18.572	16.223	EPSD	COSMIC	16.613	Loss
Other_IKK_IKBKB_ST	Q6P2E9	EDC4	O14920	IKBKB	S809	S809F	809	Missense	central	0	yes	17.684	0.000	EPSD	COSMIC	16.613	Loss
Other_IKK_IKBKB_ST	Q6P2E9	EDC4	O14920	IKBKB	S918	S914F	914	Missense	distal	-4	no	16.950	10.715	EPSD	COSMIC	16.613	Loss
Other_IKK_IKBKB_ST	Q6P2E9	EDC4	O14920	IKBKB	S918	K912N	912	Missense	distal	-6	no	16.950	16.934	EPSD	COSMIC	16.613	Down-regulation
Other_IKK_IKBKB_ST	Q6P2E9	EDC4	O14920	IKBKB	S936	L938H	938	Missense	proximal	2	no	19.893	19.889	EPSD	COSMIC	16.613	Down-regulation
Other_IKK_IKBKB_ST	Q6P2E9	EDC4	O14920	IKBKB	S1154	M1156R	1156	Missense	proximal	2	no	19.924	18.868	EPSD	COSMIC	16.613	Down-regulation
Other_IKK_IKBKB_ST	Q6P2E9	EDC4	O14920	IKBKB	S1158	M1156R	1156	Missense	proximal	-2	no	26.098	26.025	EPSD	COSMIC	16.613	Down-regulation
Other_IKK_IKBKB_ST	Q6P2E9	EDC4	O14920	IKBKB	S1380	R1386Q	1386	Missense	distal	6	no	18.886	19.238	EPSD	COSMIC	16.613	Up-regulation
Other_IKK_IKBKB_ST	P42771	CDKN2A	O14920	IKBKB	S8	D14E	14	Missense	distal	6	no	17.179	17.840	PhosphoSitePlus	COSMIC	16.613	Up-regulation
Other_IKK_IKBKB_ST	P42771	CDKN2A	O14920	IKBKB	S8	A13D	13	Missense	distal	5	no	17.179	14.876	PhosphoSitePlus	COSMIC	16.613	Loss
Other_IKK_IKBKB_ST	P42771	CDKN2A	O14920	IKBKB	S8	G6W	6	Missense	proximal	-2	no	17.179	16.922	PhosphoSitePlus	COSMIC	16.613	Down-regulation
Other_IKK_IKBKB_ST	P42771	CDKN2A	O14920	IKBKB	S8	D14N	14	Missense	distal	6	no	17.179	17.824	PhosphoSitePlus	COSMIC	16.613	Up-regulation
Other_IKK_IKBKB_ST	P42771	CDKN2A	O14920	IKBKB	S8	A5T	5	Missense	distal	-3	no	17.179	17.127	PhosphoSitePlus	COSMIC	16.613	Down-regulation
Other_IKK_IKBKB_ST	P42771	CDKN2A	O14920	IKBKB	S8	W15L	15	Missense	distal	7	no	17.179	18.172	PhosphoSitePlus	COSMIC	16.613	Up-regulation
Other_IKK_IKBKB_ST	P42771	CDKN2A	O14920	IKBKB	S8	S7R	7	Missense	proximal	-1	no	17.179	17.345	PhosphoSitePlus	COSMIC	16.613	Up-regulation
Other_IKK_IKBKB_ST	P42771	CDKN2A	O14920	IKBKB	S8	E2K	2	Missense	distal	-6	no	17.179	17.002	PhosphoSitePlus	COSMIC	16.613	Down-regulation
Other_IKK_IKBKB_ST	P42771	CDKN2A	O14920	IKBKB	S8	M9I	9	Missense	proximal	1	no	17.179	19.518	PhosphoSitePlus	COSMIC	16.613	Up-regulation
Other_IKK_IKBKB_ST	P42771	CDKN2A	O14920	IKBKB	S8	E10V	10	Missense	proximal	2	no	17.179	16.807	PhosphoSitePlus	COSMIC	16.613	Down-regulation
Other_IKK_IKBKB_ST	P42771	CDKN2A	O14920	IKBKB	S8	P11S	11	Missense	distal	3	no	17.179	18.514	PhosphoSitePlus	COSMIC	16.613	Up-regulation
Other_IKK_IKBKB_ST	P42771	CDKN2A	O14920	IKBKB	S8	D14V	14	Missense	distal	6	no	17.179	18.426	PhosphoSitePlus	COSMIC	16.613	Up-regulation
Other_IKK_IKBKB_ST	P42771	CDKN2A	O14920	IKBKB	S8	A4T	4	Missense	distal	-4	no	17.179	17.620	PhosphoSitePlus	COSMIC	16.613	Up-regulation
Other_IKK_IKBKB_ST	P42771	CDKN2A	O14920	IKBKB	S8	A4S	4	Missense	distal	-4	no	17.179	21.321	PhosphoSitePlus	COSMIC	16.613	Up-regulation
Other_IKK_IKBKB_ST	P42771	CDKN2A	O14920	IKBKB	S8	S7C	7	Missense	proximal	-1	no	17.179	17.479	PhosphoSitePlus	COSMIC	16.613	Up-regulation
Other_IKK_IKBKB_ST	P42771	CDKN2A	O14920	IKBKB	S8	E10G	10	Missense	proximal	2	no	17.179	15.889	PhosphoSitePlus	COSMIC	16.613	Loss
Other_IKK_IKBKB_ST	P42771	CDKN2A	O14920	IKBKB	S8	G6E	6	Missense	proximal	-2	no	17.179	16.111	PhosphoSitePlus	COSMIC	16.613	Loss
Other_IKK_IKBKB_ST	P42771	CDKN2A	O14920	IKBKB	S56	A60E	60	Missense	distal	4	no	13.964	18.450	EPSD	COSMIC	16.613	Gain
Other_IKK_IKBKB_ST	P42771	CDKN2A	O14920	IKBKB	S56	V59G	59	Missense	distal	3	no	13.964	18.053	EPSD	COSMIC	16.613	Gain
Other_IKK_IKBKB_ST	P42771	CDKN2A	O14920	IKBKB	S56	V59M	59	Missense	distal	3	no	13.964	18.581	EPSD	COSMIC	16.613	Gain
Other_IKK_IKBKB_ST	P42771	CDKN2A	O14920	IKBKB	S56	I49M	49	Missense	distal	-7	no	13.964	17.271	EPSD	COSMIC	16.613	Gain
Other_IKK_IKBKB_ST	Q9Y6K9	IKBKG	O14920	IKBKB	S252	G251D	251	Missense	proximal	-1	no	21.247	21.159	EPSD	COSMIC	16.613	Down-regulation
Other_IKK_IKBKB_ST	P21580	TNFAIP3	O14920	IKBKB	S128	L130I	130	Missense	proximal	2	no	20.968	20.806	EPSD	COSMIC;GDSC;CCLE	16.613	Down-regulation
Other_IKK_IKBKB_ST	P21580	TNFAIP3	O14920	IKBKB	S128	K131Q	131	Missense	distal	3	no	20.968	19.090	EPSD	COSMIC	16.613	Down-regulation
Other_IKK_IKBKB_ST	P21580	TNFAIP3	O14920	IKBKB	S128	K131R	131	Missense	distal	3	no	20.968	20.895	EPSD	COSMIC	16.613	Down-regulation
Other_IKK_IKBKB_ST	P21580	TNFAIP3	O14920	IKBKB	S128	T129M	129	Missense	proximal	1	no	20.968	21.494	EPSD	COSMIC	16.613	Up-regulation
Other_IKK_IKBKB_ST	P21580	TNFAIP3	O14920	IKBKB	S128	T135K	135	Missense	distal	7	no	20.968	21.631	EPSD	COSMIC	16.613	Up-regulation
Other_IKK_IKBKB_ST	P21580	TNFAIP3	O14920	IKBKB	S217	G221C	221	Missense	distal	4	no	16.101	17.121	EPSD	COSMIC	16.613	Gain
Other_IKK_IKBKB_ST	P21580	TNFAIP3	O14920	IKBKB	S381	V377M	377	Missense	distal	-4	no	8.018	18.780	PhosphoSitePlus	COSMIC;GDSC;CCLE	16.613	Gain
Other_IKK_IKBKB_ST	P21580	TNFAIP3	O14920	IKBKB	S550	T544I	544	Missense	distal	-6	no	22.636	21.527	EPSD	COSMIC	16.613	Down-regulation
Other_IKK_IKBKB_ST	P21580	TNFAIP3	O14920	IKBKB	S550	A547T	547	Missense	distal	-3	no	22.636	22.585	EPSD	COSMIC	16.613	Down-regulation
Other_IKK_IKBKB_ST	P21580	TNFAIP3	O14920	IKBKB	S550	T544A	544	Missense	distal	-6	no	22.636	22.782	EPSD	COSMIC;CCLE	16.613	Up-regulation
Other_IKK_IKBKB_ST	P21580	TNFAIP3	O14920	IKBKB	S573	P574L	574	Missense	proximal	1	no	20.858	20.566	EPSD	COSMIC	16.613	Down-regulation
Other_IKK_IKBKB_ST	P21580	TNFAIP3	O14920	IKBKB	S573	P576L	576	Missense	distal	3	no	20.858	19.242	EPSD	COSMIC	16.613	Down-regulation
Other_IKK_IKBKB_ST	P21580	TNFAIP3	O14920	IKBKB	S573	S578C	578	Missense	distal	5	no	20.858	18.531	EPSD	COSMIC	16.613	Down-regulation
Other_IKK_IKBKB_ST	P21580	TNFAIP3	O14920	IKBKB	S573	P574S	574	Missense	proximal	1	no	20.858	19.797	EPSD	COSMIC	16.613	Down-regulation
Other_IKK_IKBKB_ST	P21580	TNFAIP3	O14920	IKBKB	S573	V571I	571	Missense	proximal	-2	no	20.858	21.619	EPSD	COSMIC	16.613	Up-regulation
Other_IKK_IKBKB_ST	P21580	TNFAIP3	O14920	IKBKB	S645	S645F	645	Missense	central	0	yes	18.626	0.000	EPSD	COSMIC	16.613	Loss
Other_IKK_IKBKB_ST	P21580	TNFAIP3	O14920	IKBKB	S645	T647P	647	Missense	proximal	2	no	18.626	18.248	EPSD	COSMIC	16.613	Down-regulation
Other_IKK_IKBKB_ST	P21580	TNFAIP3	O14920	IKBKB	S645	P646S	646	Missense	proximal	1	no	18.626	17.564	EPSD	COSMIC	16.613	Down-regulation
Other_IKK_IKBKB_ST	P21580	TNFAIP3	O14920	IKBKB	S645	T647I	647	Missense	proximal	2	no	18.626	18.221	EPSD	COSMIC	16.613	Down-regulation
Other_IKK_IKBKB_ST	P21580	TNFAIP3	O14920	IKBKB	S645	Q652E	652	Missense	distal	7	no	18.626	19.196	EPSD	COSMIC	16.613	Up-regulation
Other_IKK_IKBKB_ST	P21580	TNFAIP3	O14920	IKBKB	S645	A648S	648	Missense	distal	3	no	18.626	20.068	EPSD	COSMIC;GDSC;CCLE	16.613	Up-regulation
Other_IKK_IKBKB_ST	P21580	TNFAIP3	O14920	IKBKB	S645	S649F	649	Missense	distal	4	no	18.626	15.013	EPSD	COSMIC	16.613	Loss
Other_IKK_IKBKB_ST	P21580	TNFAIP3	O14920	IKBKB	S698	R702I	702	Missense	distal	4	no	18.728	16.128	EPSD	COSMIC	16.613	Loss
Other_IKK_IKBKB_ST	P21580	TNFAIP3	O14920	IKBKB	S698	R701H	701	Missense	distal	3	no	18.728	18.850	EPSD	COSMIC;GDSC;CCLE	16.613	Up-regulation
Other_IKK_IKBKB_ST	P21580	TNFAIP3	O14920	IKBKB	S698	E693K	693	Missense	distal	-5	no	18.728	18.734	EPSD	COSMIC;GDSC;CCLE	16.613	Up-regulation
Other_IKK_IKBKB_ST	P21580	TNFAIP3	O14920	IKBKB	S698	D703G	703	Missense	distal	5	no	18.728	17.403	EPSD	COSMIC	16.613	Down-regulation
Other_IKK_IKBKB_ST	P21580	TNFAIP3	O14920	IKBKB	S698	R702T	702	Missense	distal	4	no	18.728	17.789	EPSD	COSMIC	16.613	Down-regulation
Other_IKK_IKBKB_ST	Q9Y4G8	RAPGEF2	O14920	IKBKB	S698	E700K	700	Missense	proximal	2	no	16.765	16.887	EPSD	COSMIC;GDSC;CCLE	16.613	Up-regulation
Other_IKK_IKBKB_ST	Q9Y4G8	RAPGEF2	O14920	IKBKB	S698	S698N	698	Missense	central	0	yes	16.765	0.000	EPSD	COSMIC	16.613	Loss
Other_IKK_IKBKB_ST	Q9Y4G8	RAPGEF2	O14920	IKBKB	S912	N914S	914	Missense	proximal	2	no	17.157	17.191	EPSD	COSMIC	16.613	Up-regulation
Other_IKK_IKBKB_ST	Q9Y4G8	RAPGEF2	O14920	IKBKB	S930	G932E	932	Missense	proximal	2	no	15.657	16.947	EPSD	COSMIC;GDSC	16.613	Gain
Other_IKK_IKBKB_ST	Q9Y4G8	RAPGEF2	O14920	IKBKB	S1019	D1013Y	1013	Missense	distal	-6	no	19.427	18.305	EPSD	COSMIC	16.613	Down-regulation
Other_IKK_IKBKB_ST	Q9Y4G8	RAPGEF2	O14920	IKBKB	S1019	P1023Q	1023	Missense	distal	4	no	19.427	21.056	EPSD	COSMIC;GDSC;CCLE	16.613	Up-regulation
Other_IKK_IKBKB_ST	Q9Y4G8	RAPGEF2	O14920	IKBKB	S1019	G1012C	1012	Missense	distal	-7	no	19.427	17.858	EPSD	COSMIC	16.613	Down-regulation
Other_IKK_IKBKB_ST	Q9Y4G8	RAPGEF2	O14920	IKBKB	S1019	P1023H	1023	Missense	distal	4	no	19.427	18.157	EPSD	COSMIC	16.613	Down-regulation
Other_IKK_IKBKB_ST	Q9Y4G8	RAPGEF2	O14920	IKBKB	S1022	P1023Q	1023	Missense	proximal	1	no	18.520	18.616	EPSD	COSMIC;GDSC;CCLE	16.613	Up-regulation
Other_IKK_IKBKB_ST	Q9Y4G8	RAPGEF2	O14920	IKBKB	S1022	P1023H	1023	Missense	proximal	1	no	18.520	18.440	EPSD	COSMIC	16.613	Down-regulation
Other_IKK_IKBKB_ST	Q9Y4G8	RAPGEF2	O14920	IKBKB	S1089	K1086R	1086	Missense	distal	-3	no	27.957	27.687	EPSD	COSMIC	16.613	Down-regulation
Other_IKK_IKBKB_ST	Q9Y4G8	RAPGEF2	O14920	IKBKB	S1089	L1096F	1096	Missense	distal	7	no	27.957	27.454	EPSD	COSMIC	16.613	Down-regulation
Other_IKK_IKBKB_ST	Q9Y4G8	RAPGEF2	O14920	IKBKB	S1089	S1095F	1095	Missense	distal	6	no	27.957	30.050	EPSD	COSMIC	16.613	Up-regulation
Other_IKK_IKBKB_ST	Q9Y4G8	RAPGEF2	O14920	IKBKB	S1095	H1099D	1099	Missense	distal	4	no	19.879	20.497	EPSD	COSMIC	16.613	Up-regulation
Other_IKK_IKBKB_ST	Q9Y4G8	RAPGEF2	O14920	IKBKB	S1095	R1098C	1098	Missense	distal	3	no	19.879	18.241	EPSD	COSMIC	16.613	Down-regulation
Other_IKK_IKBKB_ST	Q9Y4G8	RAPGEF2	O14920	IKBKB	S1095	L1096F	1096	Missense	proximal	1	no	19.879	21.026	EPSD	COSMIC	16.613	Up-regulation
Other_IKK_IKBKB_ST	Q9Y4G8	RAPGEF2	O14920	IKBKB	S1095	S1095F	1095	Missense	central	0	yes	19.879	0.000	EPSD	COSMIC	16.613	Loss
Other_IKK_IKBKB_ST	Q9Y4G8	RAPGEF2	O14920	IKBKB	S1108	S1115Y	1115	Missense	distal	7	no	21.384	20.097	EPSD	COSMIC	16.613	Down-regulation
Other_IKK_IKBKB_ST	Q9Y4G8	RAPGEF2	O14920	IKBKB	S1112	S1115Y	1115	Missense	distal	3	no	30.875	28.842	EPSD	COSMIC	16.613	Down-regulation
Other_IKK_IKBKB_ST	Q9Y4G8	RAPGEF2	O14920	IKBKB	S1115	S1115Y	1115	Missense	central	0	yes	18.345	0.000	EPSD	COSMIC	16.613	Loss
Other_IKK_IKBKB_ST	Q9Y4G8	RAPGEF2	O14920	IKBKB	S1116	S1115Y	1115	Missense	proximal	-1	no	21.270	21.862	EPSD	COSMIC	16.613	Up-regulation
Other_IKK_IKBKB_ST	Q9Y4G8	RAPGEF2	O14920	IKBKB	S1120	S1115Y	1115	Missense	distal	-5	no	20.426	20.097	EPSD	COSMIC	16.613	Down-regulation
Other_IKK_IKBKB_ST	Q9Y4G8	RAPGEF2	O14920	IKBKB	S1166	S1159P	1159	Missense	distal	-7	no	19.186	17.912	EPSD	COSMIC	16.613	Down-regulation
Other_IKK_IKBKB_ST	Q9Y4G8	RAPGEF2	O14920	IKBKB	S1166	E1170K	1170	Missense	distal	4	no	19.186	16.327	EPSD	COSMIC	16.613	Loss
Other_IKK_IKBKB_ST	Q9Y4G8	RAPGEF2	O14920	IKBKB	S1166	S1159Y	1159	Missense	distal	-7	no	19.186	16.712	EPSD	COSMIC	16.613	Down-regulation
Other_IKK_IKBKB_ST	Q9Y4G8	RAPGEF2	O14920	IKBKB	S1223	S1223C	1223	Missense	central	0	yes	23.614	0.000	EPSD	COSMIC	16.613	Loss
Other_IKK_IKBKB_ST	Q9Y4G8	RAPGEF2	O14920	IKBKB	S1223	S1225R	1225	Missense	proximal	2	no	23.614	23.510	EPSD	COSMIC	16.613	Down-regulation
Other_IKK_IKBKB_ST	Q9Y4G8	RAPGEF2	O14920	IKBKB	S1225	S1223C	1223	Missense	proximal	-2	no	16.336	16.852	EPSD	COSMIC	16.613	Gain
Other_IKK_IKBKB_ST	Q9Y4G8	RAPGEF2	O14920	IKBKB	S1313	E1318Q	1318	Missense	distal	5	no	22.509	21.462	EPSD	COSMIC	16.613	Down-regulation
Other_IKK_IKBKB_ST	Q9Y4G8	RAPGEF2	O14920	IKBKB	S1322	E1318Q	1318	Missense	distal	-4	no	18.220	13.357	EPSD	COSMIC	16.613	Loss
Other_IKK_IKBKB_ST	Q9Y4G8	RAPGEF2	O14920	IKBKB	S1325	E1318Q	1318	Missense	distal	-7	no	16.907	15.019	EPSD	COSMIC	16.613	Loss
Other_IKK_IKBKB_ST	Q9Y4G8	RAPGEF2	O14920	IKBKB	S1325	G1331R	1331	Missense	distal	6	no	16.907	15.853	EPSD	COSMIC	16.613	Loss
Other_IKK_IKBKB_ST	Q9Y4G8	RAPGEF2	O14920	IKBKB	S1487	T1488I	1488	Missense	proximal	1	no	17.346	20.211	EPSD	COSMIC	16.613	Up-regulation
Other_IKK_IKBKB_ST	P35568	IRS1	O14920	IKBKB	S270	R265C	265	Missense	distal	-5	no	16.872	16.660	EPSD	COSMIC	16.613	Down-regulation
Other_IKK_IKBKB_ST	P35568	IRS1	O14920	IKBKB	S270	S274P	274	Missense	distal	4	no	16.872	14.672	EPSD	COSMIC	16.613	Loss
Other_IKK_IKBKB_ST	P35568	IRS1	O14920	IKBKB	S273	S274P	274	Missense	proximal	1	no	16.209	17.270	EPSD	COSMIC	16.613	Gain
Other_IKK_IKBKB_ST	P35568	IRS1	O14920	IKBKB	S274	S274P	274	Missense	central	0	yes	20.210	0.000	EPSD	COSMIC	16.613	Loss
Other_IKK_IKBKB_ST	P35568	IRS1	O14920	IKBKB	S281	V282I	282	Missense	proximal	1	no	20.858	23.109	EPSD	COSMIC	16.613	Up-regulation
Other_IKK_IKBKB_ST	P35568	IRS1	O14920	IKBKB	S281	S274P	274	Missense	distal	-7	no	20.858	19.584	EPSD	COSMIC	16.613	Down-regulation
Other_IKK_IKBKB_ST	P35568	IRS1	O14920	IKBKB	S295	R301C	301	Missense	distal	6	no	17.269	18.368	EPSD	COSMIC	16.613	Up-regulation
Other_IKK_IKBKB_ST	P35568	IRS1	O14920	IKBKB	S295	Q296R	296	Missense	proximal	1	no	17.269	16.504	EPSD	COSMIC;GDSC	16.613	Loss
Other_IKK_IKBKB_ST	P35568	IRS1	O14920	IKBKB	S295	R302L	302	Missense	distal	7	no	17.269	17.143	EPSD	COSMIC	16.613	Down-regulation
Other_IKK_IKBKB_ST	P35568	IRS1	O14920	IKBKB	S295	L289F	289	Missense	distal	-6	no	17.269	16.756	EPSD	COSMIC	16.613	Down-regulation
Other_IKK_IKBKB_ST	P35568	IRS1	O14920	IKBKB	S295	P292S	292	Missense	distal	-3	no	17.269	17.816	EPSD	COSMIC	16.613	Up-regulation
Other_IKK_IKBKB_ST	P35568	IRS1	O14920	IKBKB	S295	P294T	294	Missense	proximal	-1	no	17.269	17.236	EPSD	COSMIC	16.613	Down-regulation
Other_IKK_IKBKB_ST	P35568	IRS1	O14920	IKBKB	S312	E306K	306	Missense	distal	-6	no	24.537	24.360	PhosphoSitePlus	COSMIC	16.613	Down-regulation
Other_IKK_IKBKB_ST	P35568	IRS1	O14920	IKBKB	S312	A310T	310	Missense	proximal	-2	no	24.537	24.753	PhosphoSitePlus	COSMIC	16.613	Up-regulation
Other_IKK_IKBKB_ST	P35568	IRS1	O14920	IKBKB	S312	P313L	313	Missense	proximal	1	no	24.537	24.245	PhosphoSitePlus	COSMIC;GDSC;CCLE	16.613	Down-regulation
Other_IKK_IKBKB_ST	P35568	IRS1	O14920	IKBKB	S312	M316V	316	Missense	distal	4	no	24.537	16.964	PhosphoSitePlus	COSMIC	16.613	Down-regulation
Other_IKK_IKBKB_ST	P35568	IRS1	O14920	IKBKB	S312	M316I	316	Missense	distal	4	no	24.537	17.041	PhosphoSitePlus	COSMIC	16.613	Down-regulation
Other_IKK_IKBKB_ST	P35568	IRS1	O14920	IKBKB	S312	I308M	308	Missense	distal	-4	no	24.537	32.182	PhosphoSitePlus	COSMIC	16.613	Up-regulation
Other_IKK_IKBKB_ST	P35568	IRS1	O14920	IKBKB	S312	A310V	310	Missense	proximal	-2	no	24.537	24.524	PhosphoSitePlus	COSMIC	16.613	Down-regulation
Other_IKK_IKBKB_ST	P35568	IRS1	O14920	IKBKB	S315	M316I	316	Missense	proximal	1	no	15.643	17.983	EPSD	COSMIC	16.613	Gain
Other_IKK_IKBKB_ST	P35568	IRS1	O14920	IKBKB	S315	I308M	308	Missense	distal	-7	no	15.643	18.950	EPSD	COSMIC	16.613	Gain
Other_IKK_IKBKB_ST	P35568	IRS1	O14920	IKBKB	S341	S341L	341	Missense	central	0	yes	18.216	0.000	EPSD	COSMIC	16.613	Loss
Other_IKK_IKBKB_ST	P35568	IRS1	O14920	IKBKB	S341	P346S	346	Missense	distal	5	no	18.216	18.416	EPSD	COSMIC	16.613	Up-regulation
Other_IKK_IKBKB_ST	P35568	IRS1	O14920	IKBKB	S345	S341L	341	Missense	distal	-4	no	16.759	10.127	EPSD	COSMIC	16.613	Loss
Other_IKK_IKBKB_ST	P35568	IRS1	O14920	IKBKB	S345	N352D	352	Missense	distal	7	no	16.759	16.743	EPSD	COSMIC	16.613	Down-regulation
Other_IKK_IKBKB_ST	P35568	IRS1	O14920	IKBKB	S345	P349L	349	Missense	distal	4	no	16.759	17.114	EPSD	COSMIC	16.613	Up-regulation
Other_IKK_IKBKB_ST	P35568	IRS1	O14920	IKBKB	S345	P346S	346	Missense	proximal	1	no	16.759	15.697	EPSD	COSMIC	16.613	Loss
Other_IKK_IKBKB_ST	P35568	IRS1	O14920	IKBKB	S380	A379P	379	Missense	proximal	-1	no	18.081	18.241	EPSD	COSMIC	16.613	Up-regulation
Other_IKK_IKBKB_ST	P35568	IRS1	O14920	IKBKB	S380	S383L	383	Missense	distal	3	no	18.081	15.129	EPSD	COSMIC	16.613	Loss
Other_IKK_IKBKB_ST	P35568	IRS1	O14920	IKBKB	S380	R381L	381	Missense	proximal	1	no	18.081	18.458	EPSD	COSMIC	16.613	Up-regulation
Other_IKK_IKBKB_ST	P35568	IRS1	O14920	IKBKB	S380	S383W	383	Missense	distal	3	no	18.081	12.537	EPSD	COSMIC	16.613	Loss
Other_IKK_IKBKB_ST	P35568	IRS1	O14920	IKBKB	S380	P384S	384	Missense	distal	4	no	18.081	20.280	EPSD	COSMIC	16.613	Up-regulation
Other_IKK_IKBKB_ST	P35568	IRS1	O14920	IKBKB	S380	S385L	385	Missense	distal	5	no	18.081	18.157	EPSD	COSMIC	16.613	Up-regulation
Other_IKK_IKBKB_ST	P35568	IRS1	O14920	IKBKB	S398	S398G	398	Missense	central	0	yes	23.451	0.000	EPSD	COSMIC	16.613	Loss
Other_IKK_IKBKB_ST	P35568	IRS1	O14920	IKBKB	S398	G401D	401	Missense	distal	3	no	23.451	23.814	EPSD	COSMIC	16.613	Up-regulation
Other_IKK_IKBKB_ST	P35568	IRS1	O14920	IKBKB	S398	T403S	403	Missense	distal	5	no	23.451	24.172	EPSD	COSMIC	16.613	Up-regulation
Other_IKK_IKBKB_ST	P35568	IRS1	O14920	IKBKB	S398	H400Q	400	Missense	proximal	2	no	23.451	23.687	EPSD	COSMIC	16.613	Up-regulation
Other_IKK_IKBKB_ST	P35568	IRS1	O14920	IKBKB	S398	S395I	395	Missense	distal	-3	no	23.451	22.516	EPSD	COSMIC;GDSC;CCLE	16.613	Down-regulation
Other_IKK_IKBKB_ST	P35568	IRS1	O14920	IKBKB	S402	S398G	398	Missense	distal	-4	no	19.297	13.021	EPSD	COSMIC	16.613	Loss
Other_IKK_IKBKB_ST	P35568	IRS1	O14920	IKBKB	S402	G401D	401	Missense	proximal	-1	no	19.297	19.208	EPSD	COSMIC	16.613	Down-regulation
Other_IKK_IKBKB_ST	P35568	IRS1	O14920	IKBKB	S402	T403S	403	Missense	proximal	1	no	19.297	19.997	EPSD	COSMIC	16.613	Up-regulation
Other_IKK_IKBKB_ST	P35568	IRS1	O14920	IKBKB	S402	H400Q	400	Missense	proximal	-2	no	19.297	19.186	EPSD	COSMIC	16.613	Down-regulation
Other_IKK_IKBKB_ST	P35568	IRS1	O14920	IKBKB	S402	S395I	395	Missense	distal	-7	no	19.297	17.054	EPSD	COSMIC;GDSC;CCLE	16.613	Down-regulation
Other_IKK_IKBKB_ST	P35568	IRS1	O14920	IKBKB	S463	E460K	460	Missense	distal	-3	no	25.203	25.595	EPSD	COSMIC	16.613	Up-regulation
Other_IKK_IKBKB_ST	P35568	IRS1	O14920	IKBKB	S463	G458A	458	Missense	distal	-5	no	25.203	25.301	EPSD	COSMIC	16.613	Up-regulation
Other_IKK_IKBKB_ST	P35568	IRS1	O14920	IKBKB	S463	M468I	468	Missense	distal	5	no	25.203	19.872	EPSD	COSMIC;GDSC;CCLE	16.613	Down-regulation
Other_IKK_IKBKB_ST	P35568	IRS1	O14920	IKBKB	S463	G470V	470	Missense	distal	7	no	25.203	24.809	EPSD	COSMIC;GDSC;CCLE	16.613	Down-regulation
Other_IKK_IKBKB_ST	P35568	IRS1	O14920	IKBKB	S531	T530A	530	Missense	proximal	-1	no	20.262	20.135	EPSD	COSMIC	16.613	Down-regulation
Other_IKK_IKBKB_ST	P35568	IRS1	O14920	IKBKB	S531	T533I	533	Missense	proximal	2	no	20.262	19.857	EPSD	COSMIC	16.613	Down-regulation
Other_IKK_IKBKB_ST	P35568	IRS1	O14920	IKBKB	S531	H536N	536	Missense	distal	5	no	20.262	20.155	EPSD	COSMIC	16.613	Down-regulation
Other_IKK_IKBKB_ST	P35568	IRS1	O14920	IKBKB	S531	H526Y	526	Missense	distal	-5	no	20.262	19.876	EPSD	COSMIC	16.613	Down-regulation
Other_IKK_IKBKB_ST	P35568	IRS1	O14920	IKBKB	S531	G529D	529	Missense	proximal	-2	no	20.262	19.147	EPSD	COSMIC	16.613	Down-regulation
Other_IKK_IKBKB_ST	P35568	IRS1	O14920	IKBKB	S531	T535A	535	Missense	distal	4	no	20.262	21.214	EPSD	COSMIC	16.613	Up-regulation
Other_IKK_IKBKB_ST	P35568	IRS1	O14920	IKBKB	S531	Q537R	537	Missense	distal	6	no	20.262	19.910	EPSD	COSMIC	16.613	Down-regulation
Other_IKK_IKBKB_ST	P35568	IRS1	O14920	IKBKB	S853	A849S	849	Missense	distal	-4	no	16.533	20.675	EPSD	COSMIC	16.613	Gain
Other_IKK_IKBKB_ST	P35568	IRS1	O14920	IKBKB	S853	R857Q	857	Missense	distal	4	no	16.533	18.527	EPSD	COSMIC	16.613	Gain
Other_IKK_IKBKB_ST	P35568	IRS1	O14920	IKBKB	S853	R854L	854	Missense	proximal	1	no	16.533	16.911	EPSD	COSMIC	16.613	Gain
Other_IKK_IKBKB_ST	P35568	IRS1	O14920	IKBKB	S853	T847A	847	Missense	distal	-6	no	16.533	16.678	EPSD	COSMIC	16.613	Gain
Other_IKK_IKBKB_ST	P35568	IRS1	O14920	IKBKB	S869	G864W	864	Missense	distal	-5	no	19.349	18.997	EPSD	COSMIC	16.613	Down-regulation
Other_IKK_IKBKB_ST	P35568	IRS1	O14920	IKBKB	S869	P872T	872	Missense	distal	3	no	19.349	19.691	EPSD	COSMIC	16.613	Up-regulation
Other_IKK_IKBKB_ST	P35568	IRS1	O14920	IKBKB	S985	P983S	983	Missense	proximal	-2	no	16.895	16.009	EPSD	COSMIC	16.613	Loss
Other_IKK_IKBKB_ST	P35568	IRS1	O14920	IKBKB	S985	S985N	985	Missense	central	0	yes	16.895	0.000	EPSD	COSMIC	16.613	Loss
Other_IKK_IKBKB_ST	P35568	IRS1	O14920	IKBKB	S985	M992K	992	Missense	distal	7	no	16.895	16.484	EPSD	COSMIC	16.613	Loss
Other_IKK_IKBKB_ST	P35568	IRS1	O14920	IKBKB	S1000	R998C	998	Missense	proximal	-2	no	18.616	19.356	EPSD	COSMIC;GDSC;CCLE	16.613	Up-regulation
Other_IKK_IKBKB_ST	P35568	IRS1	O14920	IKBKB	S1000	D1003H	1003	Missense	distal	3	no	18.616	18.267	EPSD	COSMIC	16.613	Down-regulation
Other_IKK_IKBKB_ST	P35568	IRS1	O14920	IKBKB	S1000	P997S	997	Missense	distal	-3	no	18.616	19.163	EPSD	COSMIC	16.613	Up-regulation
Other_IKK_IKBKB_ST	P35568	IRS1	O14920	IKBKB	S1037	A1042T	1042	Missense	distal	5	no	17.849	16.812	EPSD	COSMIC	16.613	Down-regulation
Other_IKK_IKBKB_ST	P35568	IRS1	O14920	IKBKB	S1037	S1043F	1043	Missense	distal	6	no	17.849	19.942	EPSD	COSMIC	16.613	Up-regulation
Other_IKK_IKBKB_ST	P35568	IRS1	O14920	IKBKB	S1043	A1042T	1042	Missense	proximal	-1	no	25.354	25.481	EPSD	COSMIC	16.613	Up-regulation
Other_IKK_IKBKB_ST	P35568	IRS1	O14920	IKBKB	S1043	A1050V	1050	Missense	distal	7	no	25.354	24.167	EPSD	COSMIC	16.613	Down-regulation
Other_IKK_IKBKB_ST	P35568	IRS1	O14920	IKBKB	S1043	S1043F	1043	Missense	central	0	yes	25.354	0.000	EPSD	COSMIC	16.613	Loss
Other_IKK_IKBKB_ST	P35568	IRS1	O14920	IKBKB	S1078	P1079S	1079	Missense	proximal	1	no	20.834	19.772	EPSD	COSMIC	16.613	Down-regulation
Other_IKK_IKBKB_ST	P35568	IRS1	O14920	IKBKB	S1078	S1078I	1078	Missense	central	0	yes	20.834	0.000	EPSD	COSMIC	16.613	Loss
Other_IKK_IKBKB_ST	P35568	IRS1	O14920	IKBKB	S1078	R1074L	1074	Missense	distal	-4	no	20.834	16.512	EPSD	COSMIC;CCLE	16.613	Loss
Other_IKK_IKBKB_ST	P35568	IRS1	O14920	IKBKB	S1078	R1074Q	1074	Missense	distal	-4	no	20.834	19.581	EPSD	COSMIC;GDSC	16.613	Down-regulation
Other_IKK_IKBKB_ST	P35568	IRS1	O14920	IKBKB	S1078	R1081C	1081	Missense	distal	3	no	20.834	19.195	EPSD	COSMIC	16.613	Down-regulation
Other_IKK_IKBKB_ST	P35568	IRS1	O14920	IKBKB	S1105	E1102K	1102	Missense	distal	-3	no	16.307	16.699	EPSD	COSMIC	16.613	Gain
Other_IKK_IKBKB_ST	P35568	IRS1	O14920	IKBKB	S1109	E1102K	1102	Missense	distal	-7	no	18.803	18.248	EPSD	COSMIC	16.613	Down-regulation
Other_IKK_IKBKB_ST	P35568	IRS1	O14920	IKBKB	S1131	G1128S	1128	Missense	distal	-3	no	16.828	17.094	EPSD	COSMIC	16.613	Up-regulation
Other_IKK_IKBKB_ST	P35568	IRS1	O14920	IKBKB	S1131	G1130S	1130	Missense	proximal	-1	no	16.828	16.438	EPSD	COSMIC	16.613	Loss
Other_IKK_IKBKB_ST	P35568	IRS1	O14920	IKBKB	S1132	G1128S	1128	Missense	distal	-4	no	12.770	19.045	EPSD	COSMIC	16.613	Gain
Other_IKK_IKBKB_ST	P35568	IRS1	O14920	IKBKB	S1134	G1130S	1130	Missense	distal	-4	no	10.863	17.139	EPSD	COSMIC	16.613	Gain
Other_IKK_IKBKB_ST	P35568	IRS1	O14920	IKBKB	S1213	G1212V	1212	Missense	proximal	-1	no	24.941	24.812	EPSD	COSMIC	16.613	Down-regulation
Other_IKK_IKBKB_ST	P35568	IRS1	O14920	IKBKB	S1213	Q1209E	1209	Missense	distal	-4	no	24.941	29.804	EPSD	COSMIC	16.613	Up-regulation
Other_IKK_IKBKB_ST	P35568	IRS1	O14920	IKBKB	S1213	R1220C	1220	Missense	distal	7	no	24.941	24.439	EPSD	COSMIC	16.613	Down-regulation
Other_IKK_IKBKB_ST	P35568	IRS1	O14920	IKBKB	S1213	H1208R	1208	Missense	distal	-5	no	24.941	24.854	EPSD	COSMIC	16.613	Down-regulation
Other_IKK_IKBKB_ST	P35568	IRS1	O14920	IKBKB	S1216	G1212V	1212	Missense	distal	-4	no	20.156	16.195	EPSD	COSMIC	16.613	Loss
Other_IKK_IKBKB_ST	P35568	IRS1	O14920	IKBKB	S1216	Q1209E	1209	Missense	distal	-7	no	20.156	22.044	EPSD	COSMIC	16.613	Up-regulation
Other_IKK_IKBKB_ST	P35568	IRS1	O14920	IKBKB	S1216	R1220C	1220	Missense	distal	4	no	20.156	18.841	EPSD	COSMIC	16.613	Down-regulation
Other_IKK_IKBKB_ST	P35568	IRS1	O14920	IKBKB	T1219	G1212V	1212	Missense	distal	-7	no	16.616	14.060	EPSD	COSMIC	16.613	Loss
Other_IKK_IKBKB_ST	P35568	IRS1	O14920	IKBKB	T1219	R1220C	1220	Missense	proximal	1	no	16.616	17.354	EPSD	COSMIC	16.613	Up-regulation
Other_IKK_IKBKB_ST	P35568	IRS1	O14920	IKBKB	T1219	D1225Y	1225	Missense	distal	6	no	16.616	17.818	EPSD	COSMIC	16.613	Up-regulation
Other_IKK_IKBKB_ST	P35568	IRS1	O14920	IKBKB	T1219	E1224Q	1224	Missense	distal	5	no	16.616	15.568	EPSD	COSMIC	16.613	Loss
Other_IKK_IKBKB_ST	P35568	IRS1	O14920	IKBKB	T1219	L1226V	1226	Missense	distal	7	no	16.616	15.863	EPSD	COSMIC	16.613	Loss
Other_IKK_IKBKB_ST	P35568	IRS1	O14920	IKBKB	S1222	R1220C	1220	Missense	proximal	-2	no	28.475	29.216	EPSD	COSMIC	16.613	Up-regulation
Other_IKK_IKBKB_ST	P35568	IRS1	O14920	IKBKB	S1222	D1225Y	1225	Missense	distal	3	no	28.475	27.314	EPSD	COSMIC	16.613	Down-regulation
Other_IKK_IKBKB_ST	P35568	IRS1	O14920	IKBKB	S1222	A1228V	1228	Missense	distal	6	no	28.475	29.270	EPSD	COSMIC	16.613	Up-regulation
Other_IKK_IKBKB_ST	P35568	IRS1	O14920	IKBKB	S1222	E1224Q	1224	Missense	proximal	2	no	28.475	27.933	EPSD	COSMIC	16.613	Down-regulation
Other_IKK_IKBKB_ST	P35568	IRS1	O14920	IKBKB	S1222	L1226V	1226	Missense	distal	4	no	28.475	25.078	EPSD	COSMIC	16.613	Down-regulation
Other_IKK_IKBKB_ST	P35568	IRS1	O14920	IKBKB	S1223	R1220C	1220	Missense	distal	-3	no	16.694	16.113	EPSD	COSMIC	16.613	Loss
Other_IKK_IKBKB_ST	P35568	IRS1	O14920	IKBKB	S1223	D1225Y	1225	Missense	proximal	2	no	16.694	16.056	EPSD	COSMIC	16.613	Loss
Other_IKK_IKBKB_ST	P35568	IRS1	O14920	IKBKB	S1223	A1228V	1228	Missense	distal	5	no	16.694	14.972	EPSD	COSMIC	16.613	Loss
Other_IKK_IKBKB_ST	P35568	IRS1	O14920	IKBKB	S1223	E1224Q	1224	Missense	proximal	1	no	16.694	17.029	EPSD	COSMIC	16.613	Up-regulation
Other_IKK_IKBKB_ST	P35568	IRS1	O14920	IKBKB	S1223	L1226V	1226	Missense	distal	3	no	16.694	14.322	EPSD	COSMIC	16.613	Loss
Other_IKK_IKBKB_ST	P35568	IRS1	O14920	IKBKB	S1227	R1220C	1220	Missense	distal	-7	no	23.038	21.221	EPSD	COSMIC	16.613	Down-regulation
Other_IKK_IKBKB_ST	P35568	IRS1	O14920	IKBKB	S1227	D1225Y	1225	Missense	proximal	-2	no	23.038	23.997	EPSD	COSMIC	16.613	Up-regulation
Other_IKK_IKBKB_ST	P35568	IRS1	O14920	IKBKB	S1227	A1228V	1228	Missense	proximal	1	no	23.038	23.377	EPSD	COSMIC	16.613	Up-regulation
Other_IKK_IKBKB_ST	P35568	IRS1	O14920	IKBKB	S1227	E1224Q	1224	Missense	distal	-3	no	23.038	22.918	EPSD	COSMIC	16.613	Down-regulation
Other_IKK_IKBKB_ST	P35568	IRS1	O14920	IKBKB	S1227	L1226V	1226	Missense	proximal	-1	no	23.038	23.452	EPSD	COSMIC	16.613	Up-regulation
Other_IKK_IKBKB_ST	P35568	IRS1	O14920	IKBKB	S1231	D1225Y	1225	Missense	distal	-6	no	27.300	26.178	EPSD	COSMIC	16.613	Down-regulation
Other_IKK_IKBKB_ST	P35568	IRS1	O14920	IKBKB	S1231	Q1235P	1235	Missense	distal	4	no	27.300	25.672	EPSD	COSMIC	16.613	Down-regulation
Other_IKK_IKBKB_ST	P35568	IRS1	O14920	IKBKB	S1231	A1228V	1228	Missense	distal	-3	no	27.300	26.842	EPSD	COSMIC	16.613	Down-regulation
Other_IKK_IKBKB_ST	P35568	IRS1	O14920	IKBKB	S1231	E1224Q	1224	Missense	distal	-7	no	27.300	25.413	EPSD	COSMIC	16.613	Down-regulation
Other_IKK_IKBKB_ST	P35568	IRS1	O14920	IKBKB	S1231	L1226V	1226	Missense	distal	-5	no	27.300	26.977	EPSD	COSMIC	16.613	Down-regulation
Other_IKK_IKBKB_ST	Q7Z434	MAVS	O14920	IKBKB	S100	P103S	103	Missense	distal	3	no	15.623	16.959	EPSD	COSMIC	16.613	Gain
Other_IKK_IKBKB_ST	Q7Z434	MAVS	O14920	IKBKB	S192	S188I	188	Missense	distal	-4	no	23.226	16.107	EPSD	COSMIC	16.613	Loss
Other_IKK_IKBKB_ST	Q7Z434	MAVS	O14920	IKBKB	S192	H195Y	195	Missense	distal	3	no	23.226	22.414	EPSD	COSMIC	16.613	Down-regulation
Other_IKK_IKBKB_ST	Q7Z434	MAVS	O14920	IKBKB	S192	L190V	190	Missense	proximal	-2	no	23.226	21.999	EPSD	COSMIC	16.613	Down-regulation
Other_IKK_IKBKB_ST	Q7Z434	MAVS	O14920	IKBKB	S192	P189T	189	Missense	distal	-3	no	23.226	23.853	EPSD	COSMIC	16.613	Up-regulation
Other_IKK_IKBKB_ST	Q7Z434	MAVS	O14920	IKBKB	S226	R232C	232	Missense	distal	6	no	16.775	17.874	EPSD	COSMIC	16.613	Up-regulation
Other_IKK_IKBKB_ST	Q7Z434	MAVS	O14920	IKBKB	S226	S226F	226	Missense	central	0	yes	16.775	0.000	EPSD	COSMIC	16.613	Loss
Other_IKK_IKBKB_ST	Q7Z434	MAVS	O14920	IKBKB	S253	V247F	247	Missense	distal	-6	no	20.346	20.862	EPSD	COSMIC	16.613	Up-regulation
Other_IKK_IKBKB_ST	Q7Z434	MAVS	O14920	IKBKB	S263	E268K	268	Missense	distal	5	no	20.310	21.173	EPSD	COSMIC	16.613	Up-regulation
Other_IKK_IKBKB_ST	Q7Z434	MAVS	O14920	IKBKB	S263	G269D	269	Missense	distal	6	no	20.310	19.395	EPSD	COSMIC	16.613	Down-regulation
Other_IKK_IKBKB_ST	Q7Z434	MAVS	O14920	IKBKB	S275	G272D	272	Missense	distal	-3	no	19.636	19.648	EPSD	COSMIC	16.613	Up-regulation
Other_IKK_IKBKB_ST	Q7Z434	MAVS	O14920	IKBKB	S275	E268K	268	Missense	distal	-7	no	19.636	19.081	EPSD	COSMIC	16.613	Down-regulation
Other_IKK_IKBKB_ST	Q7Z434	MAVS	O14920	IKBKB	S275	E279K	279	Missense	distal	4	no	19.636	16.777	EPSD	COSMIC	16.613	Down-regulation
Other_IKK_IKBKB_ST	Q7Z434	MAVS	O14920	IKBKB	S275	G269D	269	Missense	distal	-6	no	19.636	20.109	EPSD	COSMIC	16.613	Up-regulation
Other_IKK_IKBKB_ST	Q7Z434	MAVS	O14920	IKBKB	S366	K362Q	362	Missense	distal	-4	no	16.936	14.531	EPSD	COSMIC	16.613	Loss
Other_IKK_IKBKB_ST	Q7Z434	MAVS	O14920	IKBKB	S366	M367I	367	Missense	proximal	1	no	16.936	19.275	EPSD	COSMIC	16.613	Up-regulation
Other_IKK_IKBKB_ST	Q7Z434	MAVS	O14920	IKBKB	S416	E410D	410	Missense	distal	-6	no	25.672	25.132	EPSD	COSMIC	16.613	Down-regulation
Other_IKK_IKBKB_ST	Q16875	PFKFB3	O14920	IKBKB	S269	G263D	263	Missense	distal	-6	no	25.228	25.701	PhosphoSitePlus	COSMIC	16.613	Up-regulation
Other_IKK_IKBKB_ST	Q16875	PFKFB3	O14920	IKBKB	S269	L271M	271	Missense	proximal	2	no	25.228	26.302	PhosphoSitePlus	COSMIC	16.613	Up-regulation
Other_IKK_IKBKB_ST	Q16875	PFKFB3	O14920	IKBKB	S280	E287D	287	Missense	distal	7	no	19.662	18.564	EPSD	COSMIC	16.613	Down-regulation
Other_IKK_IKBKB_ST	Q16875	PFKFB3	O14920	IKBKB	S403	E405D	405	Missense	proximal	2	no	19.952	19.196	EPSD	COSMIC	16.613	Down-regulation
Other_IKK_IKBKB_ST	Q16875	PFKFB3	O14920	IKBKB	S403	A404T	404	Missense	proximal	1	no	19.952	19.679	EPSD	COSMIC	16.613	Down-regulation
Other_IKK_IKBKB_ST	Q16875	PFKFB3	O14920	IKBKB	S446	R443Q	443	Missense	distal	-3	no	22.517	22.274	EPSD	COSMIC	16.613	Down-regulation
Other_IKK_IKBKB_ST	Q16875	PFKFB3	O14920	IKBKB	S446	K451R	451	Missense	distal	5	no	22.517	18.886	EPSD	COSMIC	16.613	Down-regulation
Other_IKK_IKBKB_ST	Q16875	PFKFB3	O14920	IKBKB	S446	K450E	450	Missense	distal	4	no	22.517	25.376	EPSD	COSMIC	16.613	Up-regulation
Other_IKK_IKBKB_ST	Q16875	PFKFB3	O14920	IKBKB	S461	S467N	467	Missense	distal	6	no	17.376	18.784	EPSD	COSMIC;GDSC;CCLE	16.613	Up-regulation
Other_IKK_IKBKB_ST	Q16875	PFKFB3	O14920	IKBKB	S461	S467L	467	Missense	distal	6	no	17.376	18.583	EPSD	COSMIC	16.613	Up-regulation
Other_IKK_IKBKB_ST	Q16875	PFKFB3	O14920	IKBKB	S467	S467N	467	Missense	central	0	yes	21.267	0.000	EPSD	COSMIC;GDSC;CCLE	16.613	Loss
Other_IKK_IKBKB_ST	Q16875	PFKFB3	O14920	IKBKB	S467	S467L	467	Missense	central	0	yes	21.267	0.000	EPSD	COSMIC	16.613	Loss
Other_IKK_IKBKB_ST	Q16875	PFKFB3	O14920	IKBKB	S478	E481K	481	Missense	distal	3	no	17.623	16.595	EPSD	COSMIC	16.613	Loss
Other_IKK_IKBKB_ST	Q16875	PFKFB3	O14920	IKBKB	S485	T486P	486	Missense	proximal	1	no	21.721	23.484	EPSD	COSMIC	16.613	Up-regulation
Other_IKK_IKBKB_ST	Q16875	PFKFB3	O14920	IKBKB	S485	A488T	488	Missense	distal	3	no	21.721	22.170	EPSD	COSMIC	16.613	Up-regulation
Other_IKK_IKBKB_ST	Q16875	PFKFB3	O14920	IKBKB	S485	E481K	481	Missense	distal	-4	no	21.721	19.263	EPSD	COSMIC	16.613	Down-regulation
Other_IKK_IKBKB_ST	Q16875	PFKFB3	O14920	IKBKB	S485	S487L	487	Missense	proximal	2	no	21.721	21.600	EPSD	COSMIC	16.613	Down-regulation
Other_IKK_IKBKB_ST	Q16875	PFKFB3	O14920	IKBKB	S492	A488T	488	Missense	distal	-4	no	16.353	16.794	EPSD	COSMIC	16.613	Gain
Other_IKK_IKBKB_ST	P20749	BCL3	O14920	IKBKB	S382	R388G	388	Missense	distal	6	no	16.631	17.684	EPSD	COSMIC	16.613	Up-regulation
Other_IKK_IKBKB_ST	P20749	BCL3	O14920	IKBKB	S382	T381S	381	Missense	proximal	-1	no	16.631	16.661	EPSD	COSMIC	16.613	Up-regulation
Other_IKK_IKBKB_ST	P20749	BCL3	O14920	IKBKB	S382	P375S	375	Missense	distal	-7	no	16.631	17.904	EPSD	COSMIC	16.613	Up-regulation
Other_IKK_IKBKB_ST	P20749	BCL3	O14920	IKBKB	S382	R377Q	377	Missense	distal	-5	no	16.631	16.122	EPSD	COSMIC	16.613	Loss
Other_IKK_IKBKB_ST	P20749	BCL3	O14920	IKBKB	S382	P383H	383	Missense	proximal	1	no	16.631	16.551	EPSD	COSMIC	16.613	Loss
Other_IKK_IKBKB_ST	P20749	BCL3	O14920	IKBKB	S386	S390N	390	Missense	distal	4	no	18.533	15.666	EPSD	COSMIC	16.613	Loss
Other_IKK_IKBKB_ST	P20749	BCL3	O14920	IKBKB	S386	R388G	388	Missense	proximal	2	no	18.533	17.999	EPSD	COSMIC	16.613	Down-regulation
Other_IKK_IKBKB_ST	P20749	BCL3	O14920	IKBKB	S386	S391A	391	Missense	distal	5	no	18.533	18.849	EPSD	COSMIC	16.613	Up-regulation
Other_IKK_IKBKB_ST	P20749	BCL3	O14920	IKBKB	S386	T381S	381	Missense	distal	-5	no	18.533	18.496	EPSD	COSMIC	16.613	Down-regulation
Other_IKK_IKBKB_ST	P20749	BCL3	O14920	IKBKB	S386	P383H	383	Missense	distal	-3	no	18.533	18.946	EPSD	COSMIC	16.613	Up-regulation
Other_IKK_IKBKB_ST	P20749	BCL3	O14920	IKBKB	S387	R388G	388	Missense	proximal	1	no	15.881	16.996	EPSD	COSMIC	16.613	Gain
Other_IKK_IKBKB_ST	P20749	BCL3	O14920	IKBKB	S387	P383H	383	Missense	distal	-4	no	15.881	17.397	EPSD	COSMIC	16.613	Gain
Other_IKK_IKBKB_ST	P20749	BCL3	O14920	IKBKB	S402	P399T	399	Missense	distal	-3	no	16.899	17.525	EPSD	COSMIC	16.613	Up-regulation
Other_IKK_IKBKB_ST	P20749	BCL3	O14920	IKBKB	S402	P407R	407	Missense	distal	5	no	16.899	16.001	EPSD	COSMIC;GDSC;CCLE	16.613	Loss
Other_IKK_IKBKB_ST	P20749	BCL3	O14920	IKBKB	S402	P408S	408	Missense	distal	6	no	16.899	15.574	EPSD	COSMIC	16.613	Loss
Other_IKK_IKBKB_ST	P23396	RPS3	O14920	IKBKB	S139	K132N	132	Missense	distal	-7	no	16.180	17.098	EPSD	COSMIC	16.613	Gain
Other_IKK_IKBKB_ST	P23396	RPS3	O14920	IKBKB	S209	S209N	209	Missense	central	0	yes	19.767	0.000	PhosphoSitePlus	COSMIC	16.613	Loss
Other_IKK_IKBKB_ST	P23396	RPS3	O14920	IKBKB	S209	D206N	206	Missense	distal	-3	no	19.767	20.398	PhosphoSitePlus	COSMIC	16.613	Up-regulation
Other_IKK_IKBKB_ST	P23396	RPS3	O14920	IKBKB	S209	H207R	207	Missense	proximal	-2	no	19.767	19.249	PhosphoSitePlus	COSMIC	16.613	Down-regulation
Other_IKK_IKBKB_ST	Q96CV9	OPTN	O14920	IKBKB	S7	P5L	5	Missense	proximal	-2	no	20.135	20.021	EPSD	COSMIC	16.613	Down-regulation
Other_IKK_IKBKB_ST	Q96CV9	OPTN	O14920	IKBKB	S191	E194K	194	Missense	distal	3	no	17.322	16.294	EPSD	COSMIC;GDSC;CCLE	16.613	Loss
Other_IKK_IKBKB_ST	Q96CV9	OPTN	O14920	IKBKB	S191	I195N	195	Missense	distal	4	no	17.322	19.621	EPSD	COSMIC	16.613	Up-regulation
Other_IKK_IKBKB_ST	Q96CV9	OPTN	O14920	IKBKB	S198	I195N	195	Missense	distal	-3	no	15.454	16.766	EPSD	COSMIC	16.613	Gain
Other_IKK_IKBKB_ST	Q96CV9	OPTN	O14920	IKBKB	S234	E227K	227	Missense	distal	-7	no	20.993	20.439	EPSD	COSMIC	16.613	Down-regulation
Other_IKK_IKBKB_ST	Q96CV9	OPTN	O14920	IKBKB	S234	L236I	236	Missense	proximal	2	no	20.993	20.831	EPSD	COSMIC	16.613	Down-regulation
Other_IKK_IKBKB_ST	Q96CV9	OPTN	O14920	IKBKB	S234	L231P	231	Missense	distal	-3	no	20.993	20.855	EPSD	COSMIC	16.613	Down-regulation
Other_IKK_IKBKB_ST	Q96CV9	OPTN	O14920	IKBKB	S269	R271H	271	Missense	proximal	2	no	28.400	28.378	EPSD	COSMIC	16.613	Down-regulation
Other_IKK_IKBKB_ST	Q96CV9	OPTN	O14920	IKBKB	S281	E288D	288	Missense	distal	7	no	16.909	15.811	EPSD	COSMIC	16.613	Loss
Other_IKK_IKBKB_ST	Q96CV9	OPTN	O14920	IKBKB	S281	E283K	283	Missense	proximal	2	no	16.909	17.031	EPSD	COSMIC	16.613	Up-regulation
Other_IKK_IKBKB_ST	Q96CV9	OPTN	O14920	IKBKB	S297	N303K	303	Missense	distal	6	no	23.857	22.158	EPSD	COSMIC	16.613	Down-regulation
Other_IKK_IKBKB_ST	Q96CV9	OPTN	O14920	IKBKB	S297	V295L	295	Missense	proximal	-2	no	23.857	25.084	EPSD	COSMIC	16.613	Up-regulation
Other_IKK_IKBKB_ST	Q96CV9	OPTN	O14920	IKBKB	S297	P292R	292	Missense	distal	-5	no	23.857	23.794	EPSD	COSMIC	16.613	Down-regulation
Other_IKK_IKBKB_ST	Q96CV9	OPTN	O14920	IKBKB	S308	N303K	303	Missense	distal	-5	no	21.406	21.103	EPSD	COSMIC	16.613	Down-regulation
Other_IKK_IKBKB_ST	Q96CV9	OPTN	O14920	IKBKB	S342	L348M	348	Missense	distal	6	no	19.486	18.712	EPSD	COSMIC	16.613	Down-regulation
Other_IKK_IKBKB_ST	Q96CV9	OPTN	O14920	IKBKB	S342	E347Q	347	Missense	distal	5	no	19.486	18.439	EPSD	COSMIC	16.613	Down-regulation
Other_IKK_IKBKB_ST	Q96CV9	OPTN	O14920	IKBKB	S342	L348F	348	Missense	distal	6	no	19.486	20.372	EPSD	COSMIC;GDSC;CCLE	16.613	Up-regulation
Other_IKK_IKBKB_ST	Q96CV9	OPTN	O14920	IKBKB	S346	L348M	348	Missense	proximal	2	no	33.424	34.497	EPSD	COSMIC	16.613	Up-regulation
Other_IKK_IKBKB_ST	Q96CV9	OPTN	O14920	IKBKB	S346	E350K	350	Missense	distal	4	no	33.424	30.565	EPSD	COSMIC	16.613	Down-regulation
Other_IKK_IKBKB_ST	Q96CV9	OPTN	O14920	IKBKB	S346	E347Q	347	Missense	proximal	1	no	33.424	33.759	EPSD	COSMIC	16.613	Up-regulation
Other_IKK_IKBKB_ST	Q96CV9	OPTN	O14920	IKBKB	S346	L348F	348	Missense	proximal	2	no	33.424	33.326	EPSD	COSMIC;GDSC;CCLE	16.613	Down-regulation
Other_IKK_IKBKB_ST	Q96CV9	OPTN	O14920	IKBKB	S513	E507K	507	Missense	distal	-6	no	22.426	22.249	PhosphoSitePlus	COSMIC	16.613	Down-regulation
Other_IKK_IKBKB_ST	Q96CV9	OPTN	O14920	IKBKB	S526	R524K	524	Missense	proximal	-2	no	17.673	17.308	EPSD	COSMIC;GDSC;CCLE	16.613	Down-regulation
Other_IKK_IKBKB_ST	O00161	SNAP23	O14920	IKBKB	S95	K91N	91	Missense	distal	-4	no	26.937	24.391	PhosphoSitePlus	COSMIC;GDSC;CCLE	16.613	Down-regulation
Other_IKK_IKBKB_ST	O00161	SNAP23	O14920	IKBKB	S95	T102P	102	Missense	distal	7	no	26.937	26.830	PhosphoSitePlus	COSMIC	16.613	Down-regulation
Other_IKK_IKBKB_ST	O43524	FOXO3	O14920	IKBKB	S7	A2V	2	Missense	distal	-5	no	18.313	17.964	EPSD	COSMIC;CCLE	16.613	Down-regulation
Other_IKK_IKBKB_ST	O43524	FOXO3	O14920	IKBKB	S7	A6S	6	Missense	proximal	-1	no	18.313	18.470	EPSD	COSMIC	16.613	Up-regulation
Other_IKK_IKBKB_ST	O43524	FOXO3	O14920	IKBKB	S55	A53G	53	Missense	proximal	-2	no	15.818	16.974	EPSD	COSMIC	16.613	Gain
Other_IKK_IKBKB_ST	O43524	FOXO3	O14920	IKBKB	S90	G86R	86	Missense	distal	-4	no	14.347	18.311	EPSD	COSMIC	16.613	Gain
Other_IKK_IKBKB_ST	O43524	FOXO3	O14920	IKBKB	S200	S203F	203	Missense	distal	3	no	16.770	12.798	EPSD	COSMIC	16.613	Loss
Other_IKK_IKBKB_ST	O43524	FOXO3	O14920	IKBKB	S200	F194Y	194	Missense	distal	-6	no	16.770	16.573	EPSD	COSMIC	16.613	Loss
Other_IKK_IKBKB_ST	O43524	FOXO3	O14920	IKBKB	S203	I210S	210	Missense	distal	7	no	18.773	19.718	EPSD	COSMIC	16.613	Up-regulation
Other_IKK_IKBKB_ST	O43524	FOXO3	O14920	IKBKB	S203	S203F	203	Missense	central	0	yes	18.773	0.000	EPSD	COSMIC	16.613	Loss
Other_IKK_IKBKB_ST	O43524	FOXO3	O14920	IKBKB	S280	Q275R	275	Missense	distal	-5	no	23.144	23.652	EPSD	COSMIC	16.613	Up-regulation
Other_IKK_IKBKB_ST	O43524	FOXO3	O14920	IKBKB	S297	P295L	295	Missense	proximal	-2	no	19.792	19.677	EPSD	COSMIC	16.613	Down-regulation
Other_IKK_IKBKB_ST	O43524	FOXO3	O14920	IKBKB	S321	S318C	318	Missense	distal	-3	no	17.349	16.929	EPSD	COSMIC	16.613	Down-regulation
Other_IKK_IKBKB_ST	O43524	FOXO3	O14920	IKBKB	S321	R323C	323	Missense	proximal	2	no	17.349	17.145	EPSD	COSMIC	16.613	Down-regulation
Other_IKK_IKBKB_ST	O43524	FOXO3	O14920	IKBKB	S321	R323H	323	Missense	proximal	2	no	17.349	17.327	EPSD	COSMIC	16.613	Down-regulation
Other_IKK_IKBKB_ST	O43524	FOXO3	O14920	IKBKB	S425	G424V	424	Missense	proximal	-1	no	21.730	21.602	EPSD	COSMIC	16.613	Down-regulation
Other_IKK_IKBKB_ST	O43524	FOXO3	O14920	IKBKB	S555	M557R	557	Missense	proximal	2	no	18.413	17.356	EPSD	COSMIC	16.613	Down-regulation
Other_IKK_IKBKB_ST	O43524	FOXO3	O14920	IKBKB	S564	M557R	557	Missense	distal	-7	no	18.329	17.734	EPSD	COSMIC	16.613	Down-regulation
Other_IKK_IKBKB_ST	O43524	FOXO3	O14920	IKBKB	S588	T582P	582	Missense	distal	-6	no	17.181	17.023	EPSD	COSMIC	16.613	Down-regulation
Other_IKK_IKBKB_ST	Q04864	REL	O14920	IKBKB	S422	P427L	427	Missense	distal	5	no	17.220	17.498	EPSD	COSMIC	16.613	Up-regulation
Other_IKK_IKBKB_ST	Q04864	REL	O14920	IKBKB	S422	H417P	417	Missense	distal	-5	no	17.220	17.196	EPSD	COSMIC	16.613	Down-regulation
Other_IKK_IKBKB_ST	Q04864	REL	O14920	IKBKB	S422	N424K	424	Missense	proximal	2	no	17.220	18.029	EPSD	COSMIC	16.613	Up-regulation
Other_IKK_IKBKB_ST	Q04864	REL	O14920	IKBKB	S422	S422P	422	Missense	central	0	yes	17.220	0.000	EPSD	COSMIC	16.613	Loss
Other_IKK_IKBKB_ST	Q04864	REL	O14920	IKBKB	S422	R421H	421	Missense	proximal	-1	no	17.220	17.134	EPSD	COSMIC	16.613	Down-regulation
Other_IKK_IKBKB_ST	Q04864	REL	O14920	IKBKB	S422	G423D	423	Missense	proximal	1	no	17.220	15.970	EPSD	COSMIC	16.613	Loss
Other_IKK_IKBKB_ST	Q04864	REL	O14920	IKBKB	S422	A416G	416	Missense	distal	-6	no	17.220	16.480	EPSD	COSMIC	16.613	Loss
Other_IKK_IKBKB_ST	Q04864	REL	O14920	IKBKB	S503	G507A	507	Missense	distal	4	no	16.245	18.593	EPSD	COSMIC	16.613	Gain
Other_IKK_IKBKB_ST	Q04864	REL	O14920	IKBKB	S516	S516N	516	Missense	central	0	yes	18.457	0.000	EPSD	COSMIC	16.613	Loss
Other_IKK_IKBKB_ST	Q04864	REL	O14920	IKBKB	S526	P530Q	530	Missense	distal	4	no	17.352	18.981	EPSD	COSMIC	16.613	Up-regulation
Other_IKK_IKBKB_ST	Q04864	REL	O14920	IKBKB	S526	L533F	533	Missense	distal	7	no	17.352	16.849	EPSD	COSMIC	16.613	Down-regulation
Other_IKK_IKBKB_ST	Q13568	IRF5	O14920	IKBKB	S156	V163M	163	Missense	distal	7	no	18.586	20.320	EPSD	COSMIC	16.613	Up-regulation
Other_IKK_IKBKB_ST	Q13568	IRF5	O14920	IKBKB	S435	E428D	428	Missense	distal	-7	no	23.765	23.288	EPSD	COSMIC	16.613	Down-regulation
Other_IKK_IKBKB_ST	Q13568	IRF5	O14920	IKBKB	S435	R442Q	442	Missense	distal	7	no	23.765	23.933	EPSD	COSMIC	16.613	Up-regulation
Other_IKK_IKBKB_ST	Q13568	IRF5	O14920	IKBKB	S446	R442Q	442	Missense	distal	-4	no	28.670	27.416	PhosphoSitePlus	COSMIC	16.613	Down-regulation
CAMK_MAPKAPK_MNK_MKNK1_ST	Q9NP80	PNPLA8	Q9BUB5	MKNK1	S106	V111F	111	Missense	distal	5	no	10.135	10.129	EPSD	COSMIC;GDSC;CCLE	8.316	Down-regulation
CAMK_MAPKAPK_MNK_MKNK1_ST	Q9NP80	PNPLA8	Q9BUB5	MKNK1	S511	S511L	511	Missense	central	0	yes	14.163	0.000	PhosphoSitePlus	COSMIC;GDSC;CCLE	8.316	Loss
CAMK_MAPKAPK_MNK_MKNK1_ST	P23246	SFPQ	Q9BUB5	MKNK1	S283	R287S	287	Missense	distal	4	no	14.701	15.244	PhosphoSitePlus;EPSD	COSMIC	8.316	Up-regulation
CAMK_MAPKAPK_MNK_MKNK1_ST	P23246	SFPQ	Q9BUB5	MKNK1	S283	N281K	281	Missense	proximal	-2	no	14.701	14.597	PhosphoSitePlus;EPSD	COSMIC	8.316	Down-regulation
CAMK_MAPKAPK_MNK_MKNK1_ST	P23246	SFPQ	Q9BUB5	MKNK1	S379	N377K	377	Missense	proximal	-2	no	9.135	9.030	EPSD	COSMIC	8.316	Down-regulation
CAMK_MAPKAPK_MNK_MKNK1_ST	P23246	SFPQ	Q9BUB5	MKNK1	S379	R376L	376	Missense	distal	-3	no	9.135	7.208	EPSD	COSMIC;CCLE	8.316	Loss
CAMK_MAPKAPK_MNK_MKNK1_ST	P23246	SFPQ	Q9BUB5	MKNK1	S379	R376C	376	Missense	distal	-3	no	9.135	6.875	EPSD	COSMIC;CCLE	8.316	Loss
CAMK_MAPKAPK_MNK_MKNK1_ST	P23246	SFPQ	Q9BUB5	MKNK1	T440	P444S	444	Missense	distal	4	no	4.874	8.344	EPSD	COSMIC;GDSC	8.316	Gain
CAMK_MAPKAPK_MNK_MKNK1_ST	P09651	HNRNPA1	Q9BUB5	MKNK1	S142	R146K	146	Missense	distal	4	no	8.361	6.943	EPSD	COSMIC	8.316	Loss
CAMK_MAPKAPK_MNK_MKNK1_ST	P09651	HNRNPA1	Q9BUB5	MKNK1	S142	T138S	138	Missense	distal	-4	no	8.361	8.957	EPSD	COSMIC	8.316	Up-regulation
CAMK_MAPKAPK_MNK_MKNK1_ST	P09651	HNRNPA1	Q9BUB5	MKNK1	S264	G257D	257	Missense	distal	-7	no	8.768	8.850	EPSD	COSMIC	8.316	Up-regulation
CAMK_MAPKAPK_MNK_MKNK1_ST	P09651	HNRNPA1	Q9BUB5	MKNK1	S264	G259S	259	Missense	distal	-5	no	8.768	8.686	EPSD	COSMIC	8.316	Down-regulation
CAMK_MAPKAPK_MNK_MKNK1_ST	P09651	HNRNPA1	Q9BUB5	MKNK1	S264	G266R	266	Missense	proximal	2	no	8.768	8.675	EPSD	COSMIC	8.316	Down-regulation
CAMK_MAPKAPK_MNK_MKNK1_ST	P09651	HNRNPA1	Q9BUB5	MKNK1	S338	G339D	339	Missense	proximal	1	no	9.296	10.130	EPSD	COSMIC	8.316	Up-regulation
CAMK_MAPKAPK_MNK_MKNK1_ST	P09651	HNRNPA1	Q9BUB5	MKNK1	S338	G343S	343	Missense	distal	5	no	9.296	9.354	EPSD	COSMIC	8.316	Up-regulation
CAMK_MAPKAPK_MNK_MKNK1_ST	P09651	HNRNPA1	Q9BUB5	MKNK1	S360	G358S	358	Missense	proximal	-2	no	8.422	9.125	EPSD	COSMIC	8.316	Up-regulation
CAMK_MAPKAPK_MNK_MKNK1_ST	P09651	HNRNPA1	Q9BUB5	MKNK1	S360	G356R	356	Missense	distal	-4	no	8.422	8.320	EPSD	COSMIC	8.316	Down-regulation
CAMK_MAPKAPK_MNK_MKNK1_ST	P09651	HNRNPA1	Q9BUB5	MKNK1	S360	S362N	362	Missense	proximal	2	no	8.422	8.609	EPSD	COSMIC	8.316	Up-regulation
CAMK_MAPKAPK_MNK_MKNK1_ST	P09651	HNRNPA1	Q9BUB5	MKNK1	S360	G355V	355	Missense	distal	-5	no	8.422	8.574	EPSD	COSMIC	8.316	Up-regulation
CAMK_MAPKAPK_MNK_MKNK1_ST	P09651	HNRNPA1	Q9BUB5	MKNK1	S360	Y366C	366	Missense	distal	6	no	8.422	8.737	EPSD	COSMIC	8.316	Up-regulation
CAMK_MAPKAPK_MNK_MKNK1_ST	P09651	HNRNPA1	Q9BUB5	MKNK1	S360	G358V	358	Missense	proximal	-2	no	8.422	7.885	EPSD	COSMIC	8.316	Loss
CAMK_MAPKAPK_MNK_MKNK1_ST	P09651	HNRNPA1	Q9BUB5	MKNK1	S361	G358S	358	Missense	distal	-3	no	8.788	9.663	EPSD	COSMIC	8.316	Up-regulation
CAMK_MAPKAPK_MNK_MKNK1_ST	P09651	HNRNPA1	Q9BUB5	MKNK1	S361	G356R	356	Missense	distal	-5	no	8.788	8.867	EPSD	COSMIC	8.316	Up-regulation
CAMK_MAPKAPK_MNK_MKNK1_ST	P09651	HNRNPA1	Q9BUB5	MKNK1	S361	S362N	362	Missense	proximal	1	no	8.788	7.451	EPSD	COSMIC	8.316	Loss
CAMK_MAPKAPK_MNK_MKNK1_ST	P09651	HNRNPA1	Q9BUB5	MKNK1	S361	G355V	355	Missense	distal	-6	no	8.788	8.780	EPSD	COSMIC	8.316	Down-regulation
CAMK_MAPKAPK_MNK_MKNK1_ST	P09651	HNRNPA1	Q9BUB5	MKNK1	S361	Y366C	366	Missense	distal	5	no	8.788	8.910	EPSD	COSMIC	8.316	Up-regulation
CAMK_MAPKAPK_MNK_MKNK1_ST	P09651	HNRNPA1	Q9BUB5	MKNK1	S361	G358V	358	Missense	distal	-3	no	8.788	7.433	EPSD	COSMIC	8.316	Loss
CAMK_MAPKAPK_MNK_MKNK1_ST	P09651	HNRNPA1	Q9BUB5	MKNK1	S362	G358S	358	Missense	distal	-4	no	12.714	12.803	EPSD;PhosphoSitePlus	COSMIC	8.316	Up-regulation
CAMK_MAPKAPK_MNK_MKNK1_ST	P09651	HNRNPA1	Q9BUB5	MKNK1	S362	G356R	356	Missense	distal	-6	no	12.714	12.715	EPSD;PhosphoSitePlus	COSMIC	8.316	Up-regulation
CAMK_MAPKAPK_MNK_MKNK1_ST	P09651	HNRNPA1	Q9BUB5	MKNK1	S362	S362N	362	Missense	central	0	yes	12.714	0.000	EPSD;PhosphoSitePlus	COSMIC	8.316	Loss
CAMK_MAPKAPK_MNK_MKNK1_ST	P09651	HNRNPA1	Q9BUB5	MKNK1	S362	G355V	355	Missense	distal	-7	no	12.714	12.660	EPSD;PhosphoSitePlus	COSMIC	8.316	Down-regulation
CAMK_MAPKAPK_MNK_MKNK1_ST	P09651	HNRNPA1	Q9BUB5	MKNK1	S362	Y366C	366	Missense	distal	4	no	12.714	12.748	EPSD;PhosphoSitePlus	COSMIC	8.316	Up-regulation
CAMK_MAPKAPK_MNK_MKNK1_ST	P09651	HNRNPA1	Q9BUB5	MKNK1	S362	G358V	358	Missense	distal	-4	no	12.714	12.038	EPSD;PhosphoSitePlus	COSMIC	8.316	Down-regulation
CAMK_MAPKAPK_MNK_MKNK1_ST	P09651	HNRNPA1	Q9BUB5	MKNK1	S363	G358S	358	Missense	distal	-5	no	13.419	13.337	EPSD;PhosphoSitePlus	COSMIC	8.316	Down-regulation
CAMK_MAPKAPK_MNK_MKNK1_ST	P09651	HNRNPA1	Q9BUB5	MKNK1	S363	G356R	356	Missense	distal	-7	no	13.419	13.377	EPSD;PhosphoSitePlus	COSMIC	8.316	Down-regulation
CAMK_MAPKAPK_MNK_MKNK1_ST	P09651	HNRNPA1	Q9BUB5	MKNK1	S363	S362N	362	Missense	proximal	-1	no	13.419	13.345	EPSD;PhosphoSitePlus	COSMIC	8.316	Down-regulation
CAMK_MAPKAPK_MNK_MKNK1_ST	P09651	HNRNPA1	Q9BUB5	MKNK1	S363	Y366C	366	Missense	distal	3	no	13.419	13.398	EPSD;PhosphoSitePlus	COSMIC	8.316	Down-regulation
CAMK_MAPKAPK_MNK_MKNK1_ST	P09651	HNRNPA1	Q9BUB5	MKNK1	S363	G358V	358	Missense	distal	-5	no	13.419	13.571	EPSD;PhosphoSitePlus	COSMIC	8.316	Up-regulation
CAMK_MAPKAPK_MNK_MKNK1_ST	P09651	HNRNPA1	Q9BUB5	MKNK1	S364	G358S	358	Missense	distal	-6	no	13.547	13.551	EPSD;PhosphoSitePlus	COSMIC	8.316	Up-regulation
CAMK_MAPKAPK_MNK_MKNK1_ST	P09651	HNRNPA1	Q9BUB5	MKNK1	S364	S362N	362	Missense	proximal	-2	no	13.547	12.855	EPSD;PhosphoSitePlus	COSMIC	8.316	Down-regulation
CAMK_MAPKAPK_MNK_MKNK1_ST	P09651	HNRNPA1	Q9BUB5	MKNK1	S364	Y366C	366	Missense	proximal	2	no	13.547	13.519	EPSD;PhosphoSitePlus	COSMIC	8.316	Down-regulation
CAMK_MAPKAPK_MNK_MKNK1_ST	P09651	HNRNPA1	Q9BUB5	MKNK1	S364	G358V	358	Missense	distal	-6	no	13.547	13.538	EPSD;PhosphoSitePlus	COSMIC	8.316	Down-regulation
CAMK_MAPKAPK_MNK_MKNK1_ST	P09651	HNRNPA1	Q9BUB5	MKNK1	S365	G358S	358	Missense	distal	-7	no	8.455	8.638	EPSD	COSMIC	8.316	Up-regulation
CAMK_MAPKAPK_MNK_MKNK1_ST	P09651	HNRNPA1	Q9BUB5	MKNK1	S365	S362N	362	Missense	distal	-3	no	8.455	7.042	EPSD	COSMIC	8.316	Loss
CAMK_MAPKAPK_MNK_MKNK1_ST	P09651	HNRNPA1	Q9BUB5	MKNK1	S365	Y366C	366	Missense	proximal	1	no	8.455	9.295	EPSD	COSMIC	8.316	Up-regulation
CAMK_MAPKAPK_MNK_MKNK1_ST	P09651	HNRNPA1	Q9BUB5	MKNK1	S365	G358V	358	Missense	distal	-7	no	8.455	8.401	EPSD	COSMIC	8.316	Down-regulation
CAMK_MAPKAPK_MNK_MKNK1_ST	O43597	SPRY2	Q9BUB5	MKNK1	S7	G8D	8	Missense	proximal	1	no	8.018	8.853	EPSD	COSMIC	8.316	Gain
CAMK_MAPKAPK_MNK_MKNK1_ST	O43597	SPRY2	Q9BUB5	MKNK1	S112	T113M	113	Missense	proximal	1	no	14.586	13.318	PhosphoSitePlus;EPSD	COSMIC	8.316	Down-regulation
CAMK_MAPKAPK_MNK_MKNK1_ST	O43597	SPRY2	Q9BUB5	MKNK1	S115	T113M	113	Missense	proximal	-2	no	8.815	8.695	EPSD	COSMIC	8.316	Down-regulation
CAMK_MAPKAPK_MNK_MKNK1_ST	O43597	SPRY2	Q9BUB5	MKNK1	S116	T113M	113	Missense	distal	-3	no	8.371	8.080	EPSD	COSMIC	8.316	Loss
CAMK_MAPKAPK_MNK_MKNK1_ST	O43597	SPRY2	Q9BUB5	MKNK1	S116	R123K	123	Missense	distal	7	no	8.371	8.358	EPSD	COSMIC	8.316	Down-regulation
CAMK_MAPKAPK_MNK_MKNK1_ST	O43597	SPRY2	Q9BUB5	MKNK1	S121	R123K	123	Missense	proximal	2	no	13.724	13.780	EPSD;PhosphoSitePlus	COSMIC	8.316	Up-regulation
CAMK_MAPKAPK_MNK_MKNK1_ST	O43597	SPRY2	Q9BUB5	MKNK1	T124	R123K	123	Missense	proximal	-1	no	9.610	9.484	EPSD	COSMIC	8.316	Down-regulation
CAMK_MAPKAPK_MNK_MKNK1_ST	O43597	SPRY2	Q9BUB5	MKNK1	T124	S130F	130	Missense	distal	6	no	9.610	8.345	EPSD	COSMIC	8.316	Down-regulation
CAMK_MAPKAPK_MNK_MKNK1_ST	O43597	SPRY2	Q9BUB5	MKNK1	S128	Q133R	133	Missense	distal	5	no	8.170	8.339	EPSD	COSMIC	8.316	Gain
CAMK_MAPKAPK_MNK_MKNK1_ST	O43597	SPRY2	Q9BUB5	MKNK1	S128	S130F	130	Missense	proximal	2	no	8.170	8.492	EPSD	COSMIC	8.316	Gain
CAMK_MAPKAPK_MNK_MKNK1_ST	O43597	SPRY2	Q9BUB5	MKNK1	S138	S141F	141	Missense	distal	3	no	8.561	8.665	EPSD	COSMIC	8.316	Up-regulation
CAMK_MAPKAPK_MNK_MKNK1_ST	O43597	SPRY2	Q9BUB5	MKNK1	S138	Q133R	133	Missense	distal	-5	no	8.561	8.504	EPSD	COSMIC	8.316	Down-regulation
CAMK_MAPKAPK_MNK_MKNK1_ST	O43597	SPRY2	Q9BUB5	MKNK1	S141	D147N	147	Missense	distal	6	no	7.819	8.706	EPSD	COSMIC	8.316	Gain
CAMK_MAPKAPK_MNK_MKNK1_ST	P06730	EIF4E	Q9BUB5	MKNK1	S209	R214G	214	Missense	distal	5	no	11.229	11.377	PhosphoSitePlus	COSMIC	8.316	Up-regulation
CAMK_MAPKAPK_MNK_MKNK1_ST	P06730	EIF4E	Q9BUB5	MKNK1	T210	R214G	214	Missense	distal	4	no	10.960	9.671	EPSD	COSMIC	8.316	Down-regulation
Other_Aur_AurB_ST	P38159	RBMX	Q96GD4	AURKB	S165	R164C	164	Missense	proximal	-1	no	0.020	0.012	EPSD	COSMIC	0.010	Down-regulation
Other_Aur_AurB_ST	P38159	RBMX	Q96GD4	AURKB	S189	R187G	187	Missense	proximal	-2	no	0.072	0.000	EPSD	COSMIC	0.010	Loss
Other_Aur_AurB_ST	P38159	RBMX	Q96GD4	AURKB	T231	R229H	229	Missense	proximal	-2	no	0.065	-0.006	EPSD	COSMIC	0.010	Loss
Other_Aur_AurB_ST	P38159	RBMX	Q96GD4	AURKB	T231	R229L	229	Missense	proximal	-2	no	0.065	-0.006	EPSD	COSMIC	0.010	Loss
Other_Aur_AurB_ST	P38159	RBMX	Q96GD4	AURKB	S284	S284L	284	Missense	central	0	yes	0.067	0.000	EPSD	COSMIC	0.010	Loss
Other_Aur_AurB_ST	P38159	RBMX	Q96GD4	AURKB	S326	G322R	322	Missense	distal	-4	no	0.074	0.075	PhosphoSitePlus	COSMIC	0.010	Up-regulation
Other_Aur_AurB_ST	P38159	RBMX	Q96GD4	AURKB	S363	S363F	363	Missense	central	0	yes	0.067	0.000	EPSD	COSMIC	0.010	Loss
Other_Aur_AurB_ST	P38159	RBMX	Q96GD4	AURKB	S380	G379R	379	Missense	proximal	-1	no	0.006	0.014	EPSD	COSMIC	0.010	Gain
Other_Aur_AurB_ST	Q9NQS7	INCENP	Q96GD4	AURKB	S50	S50N	50	Missense	central	0	yes	0.010	0.000	EPSD	COSMIC	0.010	Loss
Other_Aur_AurB_ST	Q9NQS7	INCENP	Q96GD4	AURKB	S72	R70Q	70	Missense	proximal	-2	no	0.081	0.007	EPSD;PhosphoSitePlus	COSMIC;CCLE	0.010	Loss
Other_Aur_AurB_ST	Q9NQS7	INCENP	Q96GD4	AURKB	S93	R92Q	92	Missense	proximal	-1	no	0.010	0.002	EPSD	COSMIC	0.010	Loss
Other_Aur_AurB_ST	Q9NQS7	INCENP	Q96GD4	AURKB	S94	R92Q	92	Missense	proximal	-2	no	0.070	-0.004	EPSD	COSMIC	0.010	Loss
Other_Aur_AurB_ST	Q9NQS7	INCENP	Q96GD4	AURKB	S106	S106C	106	Missense	central	0	yes	0.012	0.000	EPSD	COSMIC	0.010	Loss
Other_Aur_AurB_ST	Q9NQS7	INCENP	Q96GD4	AURKB	S223	P220H	220	Missense	distal	-3	no	0.014	0.015	EPSD	COSMIC	0.010	Up-regulation
Other_Aur_AurB_ST	Q9NQS7	INCENP	Q96GD4	AURKB	S269	S269L	269	Missense	central	0	yes	0.069	0.000	EPSD	COSMIC;GDSC	0.010	Loss
Other_Aur_AurB_ST	Q9NQS7	INCENP	Q96GD4	AURKB	S300	D299N	299	Missense	proximal	-1	no	0.009	0.010	EPSD	COSMIC	0.010	Gain
Other_Aur_AurB_ST	Q9NQS7	INCENP	Q96GD4	AURKB	S336	R333C	333	Missense	distal	-3	no	0.078	0.071	EPSD	COSMIC	0.010	Down-regulation
Other_Aur_AurB_ST	Q9NQS7	INCENP	Q96GD4	AURKB	T343	R337T	337	Missense	distal	-6	no	0.013	0.012	EPSD	COSMIC	0.010	Down-regulation
Other_Aur_AurB_ST	Q9NQS7	INCENP	Q96GD4	AURKB	S452	R451H	451	Missense	proximal	-1	no	0.028	0.021	EPSD	COSMIC	0.010	Down-regulation
Other_Aur_AurB_ST	Q9NQS7	INCENP	Q96GD4	AURKB	S828	L826R	826	Missense	proximal	-2	no	0.003	0.074	EPSD	COSMIC	0.010	Gain
Other_Aur_AurB_ST	Q14980	NUMA1	Q96GD4	AURKB	S1432	K1430T	1430	Missense	proximal	-2	no	0.013	0.005	EPSD	COSMIC	0.010	Loss
Other_Aur_AurB_ST	Q14980	NUMA1	Q96GD4	AURKB	S1432	K1430E	1430	Missense	proximal	-2	no	0.013	0.000	EPSD	COSMIC	0.010	Loss
Other_Aur_AurB_ST	Q14980	NUMA1	Q96GD4	AURKB	T1804	R1802H	1802	Missense	proximal	-2	no	0.069	-0.002	EPSD	COSMIC	0.010	Loss
Other_Aur_AurB_ST	Q14980	NUMA1	Q96GD4	AURKB	T1804	R1808C	1808	Missense	distal	4	no	0.069	0.068	EPSD	COSMIC	0.010	Down-regulation
Other_Aur_AurB_ST	Q14980	NUMA1	Q96GD4	AURKB	T1804	R1802C	1802	Missense	proximal	-2	no	0.069	-0.001	EPSD	COSMIC;GDSC	0.010	Loss
Other_Aur_AurB_ST	Q14980	NUMA1	Q96GD4	AURKB	S1806	R1802H	1802	Missense	distal	-4	no	0.016	0.015	EPSD	COSMIC	0.010	Down-regulation
Other_Aur_AurB_ST	Q14980	NUMA1	Q96GD4	AURKB	S1806	R1802C	1802	Missense	distal	-4	no	0.016	0.015	EPSD	COSMIC;GDSC	0.010	Down-regulation
Other_Aur_AurB_ST	Q14980	NUMA1	Q96GD4	AURKB	T1811	R1808C	1808	Missense	distal	-3	no	0.082	0.075	EPSD;PhosphoSitePlus	COSMIC	0.010	Down-regulation
Other_Aur_AurB_ST	Q14980	NUMA1	Q96GD4	AURKB	T1812	R1808C	1808	Missense	distal	-4	no	0.073	0.072	EPSD	COSMIC	0.010	Down-regulation
Other_Aur_AurB_ST	Q14980	NUMA1	Q96GD4	AURKB	S1840	R1839Q	1839	Missense	proximal	-1	no	0.011	0.004	EPSD	COSMIC	0.010	Loss
Other_Aur_AurB_ST	Q14980	NUMA1	Q96GD4	AURKB	S1840	T1838M	1838	Missense	proximal	-2	no	0.011	0.008	EPSD	COSMIC	0.010	Loss
Other_Aur_AurB_ST	Q14980	NUMA1	Q96GD4	AURKB	S1840	S1840F	1840	Missense	central	0	yes	0.011	0.000	EPSD	COSMIC	0.010	Loss
Other_Aur_AurB_ST	Q14980	NUMA1	Q96GD4	AURKB	T1851	S1856R	1856	Missense	distal	5	no	0.067	0.065	EPSD	COSMIC	0.010	Down-regulation
Other_Aur_AurB_ST	Q14980	NUMA1	Q96GD4	AURKB	T1851	T1851A	1851	Missense	central	0	yes	0.067	0.000	EPSD	COSMIC;GDSC;CCLE	0.010	Loss
Other_Aur_AurB_ST	Q14980	NUMA1	Q96GD4	AURKB	S1852	S1856R	1856	Missense	distal	4	no	0.012	0.013	EPSD	COSMIC	0.010	Up-regulation
Other_Aur_AurB_ST	Q14980	NUMA1	Q96GD4	AURKB	S1862	S1856R	1856	Missense	distal	-6	no	0.008	0.010	EPSD	COSMIC	0.010	Gain
Other_Aur_AurB_ST	Q14980	NUMA1	Q96GD4	AURKB	T1879	R1877C	1877	Missense	proximal	-2	no	0.064	-0.006	EPSD	COSMIC	0.010	Loss
Other_Aur_AurB_ST	Q14980	NUMA1	Q96GD4	AURKB	S1882	R1881C	1881	Missense	proximal	-1	no	0.014	0.006	EPSD	COSMIC	0.010	Loss
Other_Aur_AurB_ST	Q14980	NUMA1	Q96GD4	AURKB	S1882	R1877C	1877	Missense	distal	-5	no	0.014	0.012	EPSD	COSMIC	0.010	Down-regulation
Other_Aur_AurB_ST	Q14980	NUMA1	Q96GD4	AURKB	S1883	R1881C	1881	Missense	proximal	-2	no	0.072	0.002	EPSD	COSMIC	0.010	Loss
Other_Aur_AurB_ST	Q14980	NUMA1	Q96GD4	AURKB	S1883	R1877C	1877	Missense	distal	-6	no	0.072	0.071	EPSD	COSMIC	0.010	Down-regulation
Other_Aur_AurB_ST	Q14980	NUMA1	Q96GD4	AURKB	S1887	R1881C	1881	Missense	distal	-6	no	0.080	0.079	EPSD	COSMIC	0.010	Down-regulation
Other_Aur_AurB_ST	Q14980	NUMA1	Q96GD4	AURKB	S1887	R1885H	1885	Missense	proximal	-2	no	0.080	0.010	EPSD	COSMIC	0.010	Down-regulation
Other_Aur_AurB_ST	Q14980	NUMA1	Q96GD4	AURKB	S1901	P1897T	1897	Missense	distal	-4	no	0.069	0.070	EPSD	COSMIC	0.010	Up-regulation
Other_Aur_AurB_ST	Q14980	NUMA1	Q96GD4	AURKB	S1945	S1945F	1945	Missense	central	0	yes	0.069	0.000	EPSD	COSMIC	0.010	Loss
Other_Aur_AurB_ST	Q14980	NUMA1	Q96GD4	AURKB	S1991	R1989L	1989	Missense	proximal	-2	no	0.069	-0.001	EPSD	COSMIC	0.010	Loss
Other_Aur_AurB_ST	Q14980	NUMA1	Q96GD4	AURKB	S1991	R1989Q	1989	Missense	proximal	-2	no	0.069	-0.005	EPSD	COSMIC	0.010	Loss
Other_Aur_AurB_ST	Q14980	NUMA1	Q96GD4	AURKB	S1991	R1987C	1987	Missense	distal	-4	no	0.069	0.068	EPSD	COSMIC	0.010	Down-regulation
Other_Aur_AurB_ST	Q14980	NUMA1	Q96GD4	AURKB	S2026	R2023C	2023	Missense	distal	-3	no	0.019	0.013	EPSD	COSMIC	0.010	Down-regulation
Other_Aur_AurB_ST	Q14980	NUMA1	Q96GD4	AURKB	S2047	R2044W	2044	Missense	distal	-3	no	0.077	0.070	EPSD;PhosphoSitePlus	COSMIC	0.010	Down-regulation
Other_Aur_AurB_ST	Q14980	NUMA1	Q96GD4	AURKB	S2047	S2047L	2047	Missense	central	0	yes	0.077	0.000	EPSD;PhosphoSitePlus	COSMIC;GDSC	0.010	Loss
Other_Aur_AurB_ST	Q14980	NUMA1	Q96GD4	AURKB	S2077	R2081H	2081	Missense	distal	4	no	0.010	0.009	EPSD	COSMIC	0.010	Loss
Other_Aur_AurB_ST	Q14980	NUMA1	Q96GD4	AURKB	S2087	R2081H	2081	Missense	distal	-6	no	0.078	0.077	EPSD	COSMIC	0.010	Down-regulation
Other_Aur_AurB_ST	Q14980	NUMA1	Q96GD4	AURKB	S2087	R2086H	2086	Missense	proximal	-1	no	0.078	0.071	EPSD	COSMIC	0.010	Down-regulation
Other_Aur_AurB_ST	Q14980	NUMA1	Q96GD4	AURKB	S2087	R2085C	2085	Missense	proximal	-2	no	0.078	0.008	EPSD	COSMIC	0.010	Loss
Other_Aur_AurB_ST	Q96FF9	CDCA5	Q96GD4	AURKB	T6	T6K	6	Missense	central	0	yes	0.073	0.000	EPSD	COSMIC	0.010	Loss
Other_Aur_AurB_ST	Q96FF9	CDCA5	Q96GD4	AURKB	S21	R18K	18	Missense	distal	-3	no	0.010	0.004	EPSD	COSMIC	0.010	Loss
Other_Aur_AurB_ST	Q96FF9	CDCA5	Q96GD4	AURKB	S21	G16R	16	Missense	distal	-5	no	0.010	0.012	EPSD	COSMIC	0.010	Up-regulation
Other_Aur_AurB_ST	Q96FF9	CDCA5	Q96GD4	AURKB	S83	R81S	81	Missense	proximal	-2	no	0.072	-0.001	EPSD;PhosphoSitePlus	COSMIC	0.010	Loss
Other_Aur_AurB_ST	Q96FF9	CDCA5	Q96GD4	AURKB	S125	E123K	123	Missense	proximal	-2	no	-0.001	0.012	EPSD	COSMIC	0.010	Gain
Other_Aur_AurB_ST	Q96FF9	CDCA5	Q96GD4	AURKB	S164	S164F	164	Missense	central	0	yes	0.078	0.000	EPSD;PhosphoSitePlus	COSMIC	0.010	Loss
Other_Aur_AurB_ST	Q9H0H5	RACGAP1	Q96GD4	AURKB	T186	T186A	186	Missense	central	0	yes	0.078	0.000	EPSD	COSMIC	0.010	Loss
Other_Aur_AurB_ST	Q9H0H5	RACGAP1	Q96GD4	AURKB	S187	T186A	186	Missense	proximal	-1	no	0.009	0.010	EPSD	COSMIC	0.010	Gain
Other_Aur_AurB_ST	Q9H0H5	RACGAP1	Q96GD4	AURKB	S203	R202H	202	Missense	proximal	-1	no	0.013	0.006	EPSD	COSMIC	0.010	Loss
Other_Aur_AurB_ST	Q9H0H5	RACGAP1	Q96GD4	AURKB	S387	R391C	391	Missense	distal	4	no	0.076	0.075	PhosphoSitePlus;EPSD	COSMIC	0.010	Down-regulation
Other_Aur_AurB_ST	Q9H0H5	RACGAP1	Q96GD4	AURKB	S600	R599C	599	Missense	proximal	-1	no	0.010	0.002	EPSD	COSMIC	0.010	Loss
Other_Aur_AurB_ST	Q9H0H5	RACGAP1	Q96GD4	AURKB	T601	R599C	599	Missense	proximal	-2	no	0.070	-0.001	EPSD	COSMIC	0.010	Loss
Other_Aur_AurB_ST	O14777	NDC80	Q96GD4	AURKB	S69	S69C	69	Missense	central	0	yes	0.072	0.000	EPSD;PhosphoSitePlus	COSMIC	0.010	Loss
Other_Aur_AurB_ST	P98179	RBM3	Q96GD4	AURKB	T43	R41W	41	Missense	proximal	-2	no	0.070	0.001	EPSD	COSMIC	0.010	Loss
Other_Aur_AurB_ST	P98179	RBM3	Q96GD4	AURKB	T43	R47G	47	Missense	distal	4	no	0.070	0.069	EPSD	COSMIC	0.010	Down-regulation
Other_Aur_AurB_ST	P98179	RBM3	Q96GD4	AURKB	S147	R145C	145	Missense	proximal	-2	no	0.070	-0.001	PhosphoSitePlus	COSMIC;GDSC;CCLE	0.010	Loss
Other_Aur_AurB_ST	P98179	RBM3	Q96GD4	AURKB	S147	R145S	145	Missense	proximal	-2	no	0.070	-0.003	PhosphoSitePlus	COSMIC	0.010	Loss
Other_Aur_AurB_ST	Q8NEM2	SHCBP1	Q96GD4	AURKB	S96	K94R	94	Missense	proximal	-2	no	0.011	0.070	EPSD	COSMIC	0.010	Up-regulation
Other_Aur_AurB_ST	Q8NEM2	SHCBP1	Q96GD4	AURKB	S267	S267I	267	Missense	central	0	yes	0.071	0.000	EPSD	COSMIC;GDSC;CCLE	0.010	Loss
Other_Aur_AurB_ST	P06400	RB1	Q96GD4	AURKB	T9	P6S	6	Missense	distal	-3	no	0.069	0.070	EPSD	COSMIC	0.010	Up-regulation
Other_Aur_AurB_ST	P06400	RB1	Q96GD4	AURKB	T9	R7Q	7	Missense	proximal	-2	no	0.069	-0.004	EPSD	COSMIC	0.010	Loss
Other_Aur_AurB_ST	P06400	RB1	Q96GD4	AURKB	T9	T5S	5	Missense	distal	-4	no	0.069	0.070	EPSD	COSMIC	0.010	Up-regulation
Other_Aur_AurB_ST	P06400	RB1	Q96GD4	AURKB	S82	K80N	80	Missense	proximal	-2	no	0.011	-0.001	EPSD	COSMIC;GDSC;CCLE	0.010	Loss
Other_Aur_AurB_ST	P06400	RB1	Q96GD4	AURKB	S230	K228R	228	Missense	proximal	-2	no	0.011	0.070	EPSD	COSMIC;GDSC;CCLE	0.010	Up-regulation
Other_Aur_AurB_ST	P06400	RB1	Q96GD4	AURKB	S260	Q257R	257	Missense	distal	-3	no	0.010	0.016	EPSD	COSMIC	0.010	Up-regulation
Other_Aur_AurB_ST	P06400	RB1	Q96GD4	AURKB	S260	A264V	264	Missense	distal	4	no	0.010	0.009	EPSD	COSMIC	0.010	Loss
Other_Aur_AurB_ST	P06400	RB1	Q96GD4	AURKB	S260	A264T	264	Missense	distal	4	no	0.010	0.009	EPSD	COSMIC	0.010	Loss
Other_Aur_AurB_ST	P06400	RB1	Q96GD4	AURKB	S360	R358Q	358	Missense	proximal	-2	no	0.074	0.000	EPSD	COSMIC;CCLE	0.010	Loss
Other_Aur_AurB_ST	P06400	RB1	Q96GD4	AURKB	S414	K412N	412	Missense	proximal	-2	no	0.014	0.002	EPSD	COSMIC	0.010	Loss
Other_Aur_AurB_ST	P06400	RB1	Q96GD4	AURKB	S618	S612P	612	Missense	distal	-6	no	0.013	0.012	EPSD	COSMIC	0.010	Down-regulation
Other_Aur_AurB_ST	P06400	RB1	Q96GD4	AURKB	T778	P776R	776	Missense	proximal	-2	no	-0.001	0.073	EPSD	COSMIC	0.010	Gain
Other_Aur_AurB_ST	P06400	RB1	Q96GD4	AURKB	S816	K814T	814	Missense	proximal	-2	no	0.010	0.002	EPSD	COSMIC	0.010	Loss
Other_Aur_AurB_ST	P06400	RB1	Q96GD4	AURKB	S862	R857S	857	Missense	distal	-5	no	0.019	0.018	EPSD	COSMIC	0.010	Down-regulation
Other_Aur_AurB_ST	P06400	RB1	Q96GD4	AURKB	S862	R857L	857	Missense	distal	-5	no	0.019	0.017	EPSD	COSMIC	0.010	Down-regulation
Other_Aur_AurB_ST	P78527	PRKDC	Q96GD4	AURKB	S141	R139T	139	Missense	proximal	-2	no	0.070	0.002	EPSD	COSMIC	0.010	Loss
Other_Aur_AurB_ST	P78527	PRKDC	Q96GD4	AURKB	S511	R509H	509	Missense	proximal	-2	no	0.071	0.001	PhosphoSitePlus	COSMIC	0.010	Loss
Other_Aur_AurB_ST	P78527	PRKDC	Q96GD4	AURKB	S511	R515T	515	Missense	distal	4	no	0.071	0.070	PhosphoSitePlus	COSMIC	0.010	Down-regulation
Other_Aur_AurB_ST	P78527	PRKDC	Q96GD4	AURKB	S702	S702F	702	Missense	central	0	yes	0.011	0.000	EPSD	COSMIC	0.010	Loss
Other_Aur_AurB_ST	P78527	PRKDC	Q96GD4	AURKB	S893	R891W	891	Missense	proximal	-2	no	0.073	0.004	EPSD	COSMIC	0.010	Loss
Other_Aur_AurB_ST	P78527	PRKDC	Q96GD4	AURKB	T946	T946M	946	Missense	central	0	yes	0.011	0.000	EPSD	COSMIC	0.010	Loss
Other_Aur_AurB_ST	P78527	PRKDC	Q96GD4	AURKB	T1336	S1333R	1333	Missense	distal	-3	no	0.011	0.018	EPSD	COSMIC	0.010	Up-regulation
Other_Aur_AurB_ST	P78527	PRKDC	Q96GD4	AURKB	T1336	T1336I	1336	Missense	central	0	yes	0.011	0.000	EPSD	COSMIC	0.010	Loss
Other_Aur_AurB_ST	P78527	PRKDC	Q96GD4	AURKB	T1336	R1340L	1340	Missense	distal	4	no	0.011	0.010	EPSD	COSMIC	0.010	Down-regulation
Other_Aur_AurB_ST	P78527	PRKDC	Q96GD4	AURKB	T1336	T1336N	1336	Missense	central	0	yes	0.011	0.000	EPSD	COSMIC	0.010	Loss
Other_Aur_AurB_ST	P78527	PRKDC	Q96GD4	AURKB	S1790	R1788K	1788	Missense	proximal	-2	no	0.077	0.018	EPSD	COSMIC	0.010	Down-regulation
Other_Aur_AurB_ST	P78527	PRKDC	Q96GD4	AURKB	S1790	R1788S	1788	Missense	proximal	-2	no	0.077	0.004	EPSD	COSMIC	0.010	Loss
Other_Aur_AurB_ST	P78527	PRKDC	Q96GD4	AURKB	S2056	S2055R	2055	Missense	proximal	-1	no	0.005	0.012	EPSD	COSMIC	0.010	Gain
Other_Aur_AurB_ST	P78527	PRKDC	Q96GD4	AURKB	S2599	R2596C	2596	Missense	distal	-3	no	0.013	0.007	EPSD	COSMIC	0.010	Loss
Other_Aur_AurB_ST	P78527	PRKDC	Q96GD4	AURKB	S2599	R2598Q	2598	Missense	proximal	-1	no	0.013	0.006	EPSD	COSMIC	0.010	Loss
Other_Aur_AurB_ST	P78527	PRKDC	Q96GD4	AURKB	S2599	S2599N	2599	Missense	central	0	yes	0.013	0.000	EPSD	COSMIC	0.010	Loss
Other_Aur_AurB_ST	P78527	PRKDC	Q96GD4	AURKB	T2600	T2600A	2600	Missense	central	0	yes	0.070	0.000	EPSD	COSMIC	0.010	Loss
Other_Aur_AurB_ST	P78527	PRKDC	Q96GD4	AURKB	T2600	R2596C	2596	Missense	distal	-4	no	0.070	0.069	EPSD	COSMIC	0.010	Down-regulation
Other_Aur_AurB_ST	P78527	PRKDC	Q96GD4	AURKB	T2600	R2598Q	2598	Missense	proximal	-2	no	0.070	-0.004	EPSD	COSMIC	0.010	Loss
Other_Aur_AurB_ST	P78527	PRKDC	Q96GD4	AURKB	T2638	R2636M	2636	Missense	proximal	-2	no	0.071	0.000	EPSD	COSMIC	0.010	Loss
Other_Aur_AurB_ST	P78527	PRKDC	Q96GD4	AURKB	S2655	R2653T	2653	Missense	proximal	-2	no	0.071	0.004	EPSD	COSMIC	0.010	Loss
Other_Aur_AurB_ST	P78527	PRKDC	Q96GD4	AURKB	S2663	G2661R	2661	Missense	proximal	-2	no	-0.007	0.065	EPSD	COSMIC	0.010	Gain
Other_Aur_AurB_ST	P78527	PRKDC	Q96GD4	AURKB	S2740	L2739P	2739	Missense	proximal	-1	no	0.012	0.011	EPSD	COSMIC	0.010	Down-regulation
Other_Aur_AurB_ST	P78527	PRKDC	Q96GD4	AURKB	S2740	Q2736R	2736	Missense	distal	-4	no	0.012	0.013	EPSD	COSMIC	0.010	Up-regulation
Other_Aur_AurB_ST	P78527	PRKDC	Q96GD4	AURKB	T2987	E2985K	2985	Missense	proximal	-2	no	-0.003	0.010	EPSD	COSMIC	0.010	Gain
Other_Aur_AurB_ST	P78527	PRKDC	Q96GD4	AURKB	T3127	V3132A	3132	Missense	distal	5	no	0.068	0.067	EPSD	COSMIC	0.010	Down-regulation
Other_Aur_AurB_ST	P78527	PRKDC	Q96GD4	AURKB	T3198	E3195K	3195	Missense	distal	-3	no	0.010	0.011	EPSD	COSMIC	0.010	Up-regulation
Other_Aur_AurB_ST	P78527	PRKDC	Q96GD4	AURKB	T3198	P3201S	3201	Missense	distal	3	no	0.010	0.009	EPSD	COSMIC	0.010	Loss
Other_Aur_AurB_ST	P78527	PRKDC	Q96GD4	AURKB	T3198	L3197R	3197	Missense	proximal	-1	no	0.010	0.017	EPSD	COSMIC	0.010	Up-regulation
Other_Aur_AurB_ST	P78527	PRKDC	Q96GD4	AURKB	S3237	S3237F	3237	Missense	central	0	yes	0.012	0.000	EPSD	COSMIC	0.010	Loss
Other_Aur_AurB_ST	P78527	PRKDC	Q96GD4	AURKB	S3253	N3251K	3251	Missense	proximal	-2	no	0.004	0.015	EPSD	COSMIC	0.010	Gain
Other_Aur_AurB_ST	P78527	PRKDC	Q96GD4	AURKB	S3290	R3287Q	3287	Missense	distal	-3	no	0.011	0.004	EPSD	COSMIC	0.010	Loss
Other_Aur_AurB_ST	P78527	PRKDC	Q96GD4	AURKB	S3290	R3289W	3289	Missense	proximal	-1	no	0.011	0.004	EPSD	COSMIC	0.010	Loss
Other_Aur_AurB_ST	P78527	PRKDC	Q96GD4	AURKB	S3657	M3654R	3654	Missense	distal	-3	no	0.013	0.020	EPSD	COSMIC	0.010	Up-regulation
Other_Aur_AurB_ST	P78527	PRKDC	Q96GD4	AURKB	T3727	G3721R	3721	Missense	distal	-6	no	0.067	0.068	EPSD	COSMIC	0.010	Up-regulation
Other_Aur_AurB_ST	P78527	PRKDC	Q96GD4	AURKB	T3727	R3725W	3725	Missense	proximal	-2	no	0.067	-0.002	EPSD	COSMIC	0.010	Loss
Other_Aur_AurB_ST	P78527	PRKDC	Q96GD4	AURKB	S3891	S3891C	3891	Missense	central	0	yes	0.072	0.000	EPSD	COSMIC	0.010	Loss
Other_Aur_AurB_ST	P78527	PRKDC	Q96GD4	AURKB	T3977	T3977M	3977	Missense	central	0	yes	0.013	0.000	EPSD	COSMIC	0.010	Loss
Other_Aur_AurB_ST	P78527	PRKDC	Q96GD4	AURKB	T3977	G3978D	3978	Missense	proximal	1	no	0.013	0.012	EPSD	COSMIC	0.010	Down-regulation
Other_Aur_AurB_ST	P78527	PRKDC	Q96GD4	AURKB	S4084	R4082Q	4082	Missense	proximal	-2	no	0.071	-0.003	EPSD	COSMIC	0.010	Loss
Other_Aur_AurB_ST	P78527	PRKDC	Q96GD4	AURKB	S4084	R4082P	4082	Missense	proximal	-2	no	0.071	-0.004	EPSD	COSMIC	0.010	Loss
Other_Aur_AurB_ST	Q12888	TP53BP1	Q96GD4	AURKB	S119	G122E	122	Missense	distal	3	no	0.011	0.010	EPSD	COSMIC	0.010	Down-regulation
Other_Aur_AurB_ST	Q12888	TP53BP1	Q96GD4	AURKB	S888	S888A	888	Missense	central	0	yes	0.012	0.000	EPSD	COSMIC	0.010	Loss
Other_Aur_AurB_ST	Q12888	TP53BP1	Q96GD4	AURKB	T1134	R1132Q	1132	Missense	proximal	-2	no	0.067	-0.006	EPSD	COSMIC	0.010	Loss
Other_Aur_AurB_ST	Q12888	TP53BP1	Q96GD4	AURKB	T1184	S1183R	1183	Missense	proximal	-1	no	0.003	0.010	EPSD	COSMIC	0.010	Gain
Other_Aur_AurB_ST	Q12888	TP53BP1	Q96GD4	AURKB	S1310	R1314H	1314	Missense	distal	4	no	0.013	0.012	EPSD	COSMIC	0.010	Down-regulation
Other_Aur_AurB_ST	Q12888	TP53BP1	Q96GD4	AURKB	S1316	R1314H	1314	Missense	proximal	-2	no	0.072	0.002	EPSD	COSMIC	0.010	Loss
Other_Aur_AurB_ST	Q12888	TP53BP1	Q96GD4	AURKB	S1342	K1340R	1340	Missense	proximal	-2	no	0.014	0.073	PhosphoSitePlus	COSMIC	0.010	Up-regulation
Other_Aur_AurB_ST	Q12888	TP53BP1	Q96GD4	AURKB	S1342	R1338T	1338	Missense	distal	-4	no	0.014	0.013	PhosphoSitePlus	COSMIC	0.010	Down-regulation
Other_Aur_AurB_ST	Q12888	TP53BP1	Q96GD4	AURKB	T1409	R1407W	1407	Missense	proximal	-2	no	0.071	0.001	EPSD	COSMIC	0.010	Loss
Other_Aur_AurB_ST	Q12888	TP53BP1	Q96GD4	AURKB	T1414	R1412W	1412	Missense	proximal	-2	no	0.067	-0.002	EPSD	COSMIC	0.010	Loss
Other_Aur_AurB_ST	Q12888	TP53BP1	Q96GD4	AURKB	T1414	R1407W	1407	Missense	distal	-7	no	0.067	0.068	EPSD	COSMIC	0.010	Up-regulation
Other_Aur_AurB_ST	Q12888	TP53BP1	Q96GD4	AURKB	T1450	R1449Q	1449	Missense	proximal	-1	no	0.075	0.067	EPSD	COSMIC	0.010	Down-regulation
Other_Aur_AurB_ST	Q12888	TP53BP1	Q96GD4	AURKB	S1460	R1458H	1458	Missense	proximal	-2	no	0.079	0.008	EPSD	COSMIC	0.010	Loss
Other_Aur_AurB_ST	Q12888	TP53BP1	Q96GD4	AURKB	S1631	G1625R	1625	Missense	distal	-6	no	0.080	0.082	EPSD	COSMIC	0.010	Up-regulation
Other_Aur_AurB_ST	Q12888	TP53BP1	Q96GD4	AURKB	T1654	A1659V	1659	Missense	distal	5	no	0.014	0.015	EPSD	COSMIC	0.010	Up-regulation
Other_Aur_AurB_ST	Q12888	TP53BP1	Q96GD4	AURKB	T1654	R1651Q	1651	Missense	distal	-3	no	0.014	0.008	EPSD	COSMIC	0.010	Loss
Other_Aur_AurB_ST	Q12888	TP53BP1	Q96GD4	AURKB	S1660	P1657S	1657	Missense	distal	-3	no	0.069	0.070	EPSD	COSMIC	0.010	Up-regulation
Other_Aur_AurB_ST	Q12888	TP53BP1	Q96GD4	AURKB	S1660	A1659V	1659	Missense	proximal	-1	no	0.069	0.068	EPSD	COSMIC	0.010	Down-regulation
Other_Aur_AurB_ST	Q13761	RUNX3	Q96GD4	AURKB	S71	R68C	68	Missense	distal	-3	no	0.012	0.005	EPSD	COSMIC	0.010	Loss
Other_Aur_AurB_ST	Q13761	RUNX3	Q96GD4	AURKB	S71	R68H	68	Missense	distal	-3	no	0.012	0.005	EPSD	COSMIC	0.010	Loss
Other_Aur_AurB_ST	Q13761	RUNX3	Q96GD4	AURKB	S149	K148N	148	Missense	proximal	-1	no	0.010	0.009	EPSD	COSMIC	0.010	Loss
Other_Aur_AurB_ST	Q13761	RUNX3	Q96GD4	AURKB	S149	R146P	146	Missense	distal	-3	no	0.010	0.003	EPSD	COSMIC	0.010	Loss
Other_Aur_AurB_ST	Q13761	RUNX3	Q96GD4	AURKB	S149	R143L	143	Missense	distal	-6	no	0.010	0.009	EPSD	COSMIC	0.010	Loss
Other_Aur_AurB_ST	Q13761	RUNX3	Q96GD4	AURKB	S149	R143H	143	Missense	distal	-6	no	0.010	0.009	EPSD	COSMIC	0.010	Loss
Other_Aur_AurB_ST	Q13761	RUNX3	Q96GD4	AURKB	S149	R143C	143	Missense	distal	-6	no	0.010	0.009	EPSD	COSMIC	0.010	Loss
Other_Aur_AurB_ST	Q13761	RUNX3	Q96GD4	AURKB	S149	S144R	144	Missense	distal	-5	no	0.010	0.012	EPSD	COSMIC	0.010	Up-regulation
Other_Aur_AurB_ST	Q13761	RUNX3	Q96GD4	AURKB	T173	R178L	178	Missense	distal	5	no	0.008	0.011	EPSD;PhosphoSitePlus	COSMIC	0.010	Gain
Other_Aur_AurB_ST	Q13761	RUNX3	Q96GD4	AURKB	T173	R178W	178	Missense	distal	5	no	0.008	0.010	EPSD;PhosphoSitePlus	COSMIC	0.010	Gain
Other_Aur_AurB_ST	Q13761	RUNX3	Q96GD4	AURKB	T173	R178Q	178	Missense	distal	5	no	0.008	0.010	EPSD;PhosphoSitePlus	COSMIC	0.010	Gain
Other_Aur_AurB_ST	Q13761	RUNX3	Q96GD4	AURKB	T209	R205C	205	Missense	distal	-4	no	0.070	0.069	EPSD	COSMIC	0.010	Down-regulation
Other_Aur_AurB_ST	Q13761	RUNX3	Q96GD4	AURKB	T209	R216Q	216	Missense	distal	7	no	0.070	0.069	EPSD	COSMIC	0.010	Down-regulation
Other_Aur_AurB_ST	Q13761	RUNX3	Q96GD4	AURKB	T209	R203L	203	Missense	distal	-6	no	0.070	0.068	EPSD	COSMIC	0.010	Down-regulation
Other_Aur_AurB_ST	Q13761	RUNX3	Q96GD4	AURKB	T209	R205H	205	Missense	distal	-4	no	0.070	0.069	EPSD	COSMIC	0.010	Down-regulation
Other_Aur_AurB_ST	Q13761	RUNX3	Q96GD4	AURKB	S218	S223R	223	Missense	distal	5	no	0.068	0.066	EPSD	COSMIC	0.010	Down-regulation
Other_Aur_AurB_ST	Q13761	RUNX3	Q96GD4	AURKB	S218	R216Q	216	Missense	proximal	-2	no	0.068	-0.006	EPSD	COSMIC	0.010	Loss
Other_Aur_AurB_ST	Q13761	RUNX3	Q96GD4	AURKB	S251	D249N	249	Missense	proximal	-2	no	0.009	0.012	EPSD	COSMIC	0.010	Gain
Other_Aur_AurB_ST	Q53HL2	CDCA8	Q96GD4	AURKB	S7	R4S	4	Missense	distal	-3	no	0.018	0.011	EPSD	COSMIC	0.010	Down-regulation
Other_Aur_AurB_ST	Q53HL2	CDCA8	Q96GD4	AURKB	S164	R163G	163	Missense	proximal	-1	no	0.016	0.008	EPSD	COSMIC	0.010	Loss
Other_Aur_AurB_ST	Q53HL2	CDCA8	Q96GD4	AURKB	S165	R163G	163	Missense	proximal	-2	no	0.071	-0.001	EPSD;PhosphoSitePlus	COSMIC	0.010	Loss
Other_Aur_AurB_ST	Q53HL2	CDCA8	Q96GD4	AURKB	S238	G236R	236	Missense	proximal	-2	no	-0.001	0.070	EPSD	COSMIC	0.010	Gain
Other_Aur_AurB_ST	Q96K21	ZFYVE19	Q96GD4	AURKB	S22	R19T	19	Missense	distal	-3	no	0.076	0.069	PhosphoSitePlus	COSMIC;GDSC	0.010	Down-regulation
Other_Aur_AurB_ST	Q96K21	ZFYVE19	Q96GD4	AURKB	S144	S144C	144	Missense	central	0	yes	0.011	0.000	EPSD	COSMIC	0.010	Loss
Other_Aur_AurB_ST	Q96K21	ZFYVE19	Q96GD4	AURKB	T345	R343T	343	Missense	proximal	-2	no	0.064	-0.003	EPSD	COSMIC	0.010	Loss
Other_Aur_AurB_ST	O00571	DDX3X	Q96GD4	AURKB	S76	G73R	73	Missense	distal	-3	no	0.003	0.010	EPSD	COSMIC	0.010	Gain
Other_Aur_AurB_ST	O00571	DDX3X	Q96GD4	AURKB	S82	R79K	79	Missense	distal	-3	no	0.010	0.004	EPSD	COSMIC	0.010	Loss
Other_Aur_AurB_ST	O00571	DDX3X	Q96GD4	AURKB	S83	R79K	79	Missense	distal	-4	no	0.012	0.011	EPSD	COSMIC	0.010	Down-regulation
Other_Aur_AurB_ST	O00571	DDX3X	Q96GD4	AURKB	S83	R88C	88	Missense	distal	5	no	0.012	0.014	EPSD	COSMIC	0.010	Up-regulation
Other_Aur_AurB_ST	O00571	DDX3X	Q96GD4	AURKB	S90	R88C	88	Missense	proximal	-2	no	0.066	-0.004	EPSD	COSMIC	0.010	Loss
Other_Aur_AurB_ST	O00571	DDX3X	Q96GD4	AURKB	S90	G89R	89	Missense	proximal	-1	no	0.066	0.073	EPSD	COSMIC	0.010	Up-regulation
Other_Aur_AurB_ST	O00571	DDX3X	Q96GD4	AURKB	S102	R99T	99	Missense	distal	-3	no	0.011	0.005	EPSD	COSMIC	0.010	Loss
Other_Aur_AurB_ST	O00571	DDX3X	Q96GD4	AURKB	T201	T198P	198	Missense	distal	-3	no	0.070	0.069	EPSD	COSMIC	0.010	Down-regulation
Other_Aur_AurB_ST	O00571	DDX3X	Q96GD4	AURKB	T204	R202L	202	Missense	proximal	-2	no	0.070	-0.001	EPSD	COSMIC	0.010	Loss
Other_Aur_AurB_ST	O00571	DDX3X	Q96GD4	AURKB	T231	G229R	229	Missense	proximal	-2	no	-0.005	0.067	EPSD	COSMIC	0.010	Gain
Other_Aur_AurB_ST	O00571	DDX3X	Q96GD4	AURKB	S290	R294T	294	Missense	distal	4	no	0.017	0.016	EPSD	COSMIC;CCLE	0.010	Down-regulation
Other_Aur_AurB_ST	O00571	DDX3X	Q96GD4	AURKB	S290	R296C	296	Missense	distal	6	no	0.017	0.016	EPSD	COSMIC	0.010	Down-regulation
Other_Aur_AurB_ST	O00571	DDX3X	Q96GD4	AURKB	S290	R292L	292	Missense	proximal	2	no	0.017	0.016	EPSD	COSMIC	0.010	Down-regulation
Other_Aur_AurB_ST	O00571	DDX3X	Q96GD4	AURKB	S290	S290F	290	Missense	central	0	yes	0.017	0.000	EPSD	COSMIC	0.010	Loss
Other_Aur_AurB_ST	O00571	DDX3X	Q96GD4	AURKB	S290	R294K	294	Missense	distal	4	no	0.017	0.016	EPSD	COSMIC	0.010	Down-regulation
Other_Aur_AurB_ST	O00571	DDX3X	Q96GD4	AURKB	S290	R287C	287	Missense	distal	-3	no	0.017	0.010	EPSD	COSMIC	0.010	Down-regulation
Other_Aur_AurB_ST	O00571	DDX3X	Q96GD4	AURKB	S290	R287H	287	Missense	distal	-3	no	0.017	0.010	EPSD	COSMIC	0.010	Down-regulation
Other_Aur_AurB_ST	O00571	DDX3X	Q96GD4	AURKB	S293	R294T	294	Missense	proximal	1	no	0.009	0.010	EPSD	COSMIC;CCLE	0.010	Gain
Other_Aur_AurB_ST	O00571	DDX3X	Q96GD4	AURKB	S293	R296C	296	Missense	distal	3	no	0.009	0.010	EPSD	COSMIC	0.010	Gain
Other_Aur_AurB_ST	O00571	DDX3X	Q96GD4	AURKB	S429	R428W	428	Missense	proximal	-1	no	0.020	0.013	EPSD	COSMIC	0.010	Down-regulation
Other_Aur_AurB_ST	O00571	DDX3X	Q96GD4	AURKB	S456	G453R	453	Missense	distal	-3	no	0.003	0.010	EPSD	COSMIC	0.010	Gain
Other_Aur_AurB_ST	O00571	DDX3X	Q96GD4	AURKB	T469	C468R	468	Missense	proximal	-1	no	0.002	0.010	EPSD	COSMIC;GDSC;CCLE	0.010	Gain
Other_Aur_AurB_ST	O00571	DDX3X	Q96GD4	AURKB	S470	C468R	468	Missense	proximal	-2	no	0.000	0.070	EPSD	COSMIC;GDSC;CCLE	0.010	Gain
Other_Aur_AurB_ST	O00571	DDX3X	Q96GD4	AURKB	S583	S583G	583	Missense	central	0	yes	0.011	0.000	EPSD	COSMIC	0.010	Loss
Other_Aur_AurB_ST	O00571	DDX3X	Q96GD4	AURKB	S583	R587Q	587	Missense	distal	4	no	0.011	0.010	EPSD	COSMIC	0.010	Down-regulation
Other_Aur_AurB_ST	O00571	DDX3X	Q96GD4	AURKB	S588	S583G	583	Missense	distal	-5	no	0.018	0.017	EPSD	COSMIC	0.010	Down-regulation
Other_Aur_AurB_ST	O00571	DDX3X	Q96GD4	AURKB	S588	S588C	588	Missense	central	0	yes	0.018	0.000	EPSD	COSMIC	0.010	Loss
Other_Aur_AurB_ST	O00571	DDX3X	Q96GD4	AURKB	S588	R587Q	587	Missense	proximal	-1	no	0.018	0.010	EPSD	COSMIC	0.010	Down-regulation
Other_Aur_AurB_ST	O00571	DDX3X	Q96GD4	AURKB	S588	R592K	592	Missense	distal	4	no	0.018	0.017	EPSD	COSMIC	0.010	Down-regulation
Other_Aur_AurB_ST	O00571	DDX3X	Q96GD4	AURKB	S588	R592I	592	Missense	distal	4	no	0.018	0.017	EPSD	COSMIC	0.010	Down-regulation
Other_Aur_AurB_ST	O00571	DDX3X	Q96GD4	AURKB	S588	R592T	592	Missense	distal	4	no	0.018	0.017	EPSD	COSMIC	0.010	Down-regulation
Other_Aur_AurB_ST	O00571	DDX3X	Q96GD4	AURKB	S588	R585H	585	Missense	distal	-3	no	0.018	0.011	EPSD	COSMIC	0.010	Down-regulation
Other_Aur_AurB_ST	O00571	DDX3X	Q96GD4	AURKB	S590	S588C	588	Missense	proximal	-2	no	0.007	0.010	EPSD	COSMIC	0.010	Gain
Other_Aur_AurB_ST	O00571	DDX3X	Q96GD4	AURKB	S591	R587Q	587	Missense	distal	-4	no	0.010	0.009	EPSD	COSMIC	0.010	Loss
Other_Aur_AurB_ST	O00571	DDX3X	Q96GD4	AURKB	S591	R585H	585	Missense	distal	-6	no	0.010	0.009	EPSD	COSMIC	0.010	Loss
Other_Aur_AurB_ST	O00571	DDX3X	Q96GD4	AURKB	S594	R592K	592	Missense	proximal	-2	no	0.067	0.008	PhosphoSitePlus	COSMIC	0.010	Loss
Other_Aur_AurB_ST	O00571	DDX3X	Q96GD4	AURKB	S594	R592I	592	Missense	proximal	-2	no	0.067	-0.005	PhosphoSitePlus	COSMIC	0.010	Loss
Other_Aur_AurB_ST	O00571	DDX3X	Q96GD4	AURKB	S594	R592T	592	Missense	proximal	-2	no	0.067	0.000	PhosphoSitePlus	COSMIC	0.010	Loss
Other_Aur_AurB_ST	O00571	DDX3X	Q96GD4	AURKB	S605	S605G	605	Missense	central	0	yes	0.070	0.000	EPSD	COSMIC	0.010	Loss
Other_Aur_AurB_ST	O00571	DDX3X	Q96GD4	AURKB	S609	G607R	607	Missense	proximal	-2	no	-0.001	0.071	EPSD	COSMIC	0.010	Gain
Other_Aur_AurB_ST	O00571	DDX3X	Q96GD4	AURKB	S610	G607R	607	Missense	distal	-3	no	0.003	0.010	EPSD	COSMIC	0.010	Gain
Other_Aur_AurB_ST	O00571	DDX3X	Q96GD4	AURKB	S619	G624R	624	Missense	distal	5	no	0.073	0.071	EPSD	COSMIC	0.010	Down-regulation
Other_Aur_AurB_ST	O00571	DDX3X	Q96GD4	AURKB	S619	R622C	622	Missense	distal	3	no	0.073	0.074	EPSD	COSMIC	0.010	Up-regulation
Other_Aur_AurB_ST	O00571	DDX3X	Q96GD4	AURKB	S619	R617K	617	Missense	proximal	-2	no	0.073	0.014	EPSD	COSMIC	0.010	Down-regulation
Other_Aur_AurB_ST	O00571	DDX3X	Q96GD4	AURKB	S619	R617I	617	Missense	proximal	-2	no	0.073	0.001	EPSD	COSMIC	0.010	Loss
Other_Aur_AurB_ST	O00571	DDX3X	Q96GD4	AURKB	S619	R617T	617	Missense	proximal	-2	no	0.073	0.006	EPSD	COSMIC	0.010	Loss
Other_Aur_AurB_ST	Q99661	KIF2C	Q96GD4	AURKB	S95	R93W	93	Missense	proximal	-2	no	0.084	0.015	EPSD;PhosphoSitePlus	COSMIC	0.010	Down-regulation
Other_Aur_AurB_ST	Q99661	KIF2C	Q96GD4	AURKB	S95	K92Q	92	Missense	distal	-3	no	0.084	0.082	EPSD;PhosphoSitePlus	COSMIC	0.010	Down-regulation
Other_Aur_AurB_ST	Q99661	KIF2C	Q96GD4	AURKB	S153	S153P	153	Missense	central	0	yes	0.068	0.000	EPSD	COSMIC	0.010	Loss
Other_Aur_AurB_ST	Q99661	KIF2C	Q96GD4	AURKB	S153	P147S	147	Missense	distal	-6	no	0.068	0.069	EPSD	COSMIC	0.010	Up-regulation
Other_Aur_AurB_ST	Q99661	KIF2C	Q96GD4	AURKB	S153	A156V	156	Missense	distal	3	no	0.068	0.069	EPSD	COSMIC	0.010	Up-regulation
Other_Aur_AurB_ST	Q99661	KIF2C	Q96GD4	AURKB	S179	S179R	179	Missense	central	0	yes	0.070	0.000	EPSD	COSMIC	0.010	Loss
Other_Aur_AurB_ST	Q99661	KIF2C	Q96GD4	AURKB	S180	S179R	179	Missense	proximal	-1	no	0.002	0.010	EPSD	COSMIC	0.010	Gain
Other_Aur_AurB_ST	Q99661	KIF2C	Q96GD4	AURKB	S181	S179R	179	Missense	proximal	-2	no	-0.004	0.069	EPSD	COSMIC	0.010	Gain
Other_Aur_AurB_ST	Q99661	KIF2C	Q96GD4	AURKB	S192	R189L	189	Missense	distal	-3	no	0.078	0.071	PhosphoSitePlus;EPSD	COSMIC	0.010	Down-regulation
Other_Aur_AurB_ST	Q99661	KIF2C	Q96GD4	AURKB	S458	R456S	456	Missense	proximal	-2	no	0.072	-0.001	EPSD	COSMIC	0.010	Loss
Other_Aur_AurB_ST	Q99661	KIF2C	Q96GD4	AURKB	S458	R456C	456	Missense	proximal	-2	no	0.072	0.001	EPSD	COSMIC	0.010	Loss
Other_Aur_AurB_ST	Q99661	KIF2C	Q96GD4	AURKB	S458	R456L	456	Missense	proximal	-2	no	0.072	0.001	EPSD	COSMIC	0.010	Loss
Other_Aur_AurB_ST	Q99661	KIF2C	Q96GD4	AURKB	S489	S489F	489	Missense	central	0	yes	0.010	0.000	EPSD	COSMIC	0.010	Loss
Other_Aur_AurB_ST	Q99661	KIF2C	Q96GD4	AURKB	S633	M631K	631	Missense	proximal	-2	no	-0.001	0.011	EPSD	COSMIC;GDSC;CCLE	0.010	Gain
Other_Aur_AurB_ST	P14136	GFAP	Q96GD4	AURKB	S424	G418R	418	Missense	distal	-6	no	0.012	0.013	EPSD	COSMIC	0.010	Up-regulation
Other_Aur_AurB_ST	Q3KR16	PLEKHG6	Q96GD4	AURKB	S537	E536K	536	Missense	proximal	-1	no	0.072	0.073	EPSD	COSMIC	0.010	Up-regulation
Other_Aur_AurB_ST	Q3KR16	PLEKHG6	Q96GD4	AURKB	S537	R531Q	531	Missense	distal	-6	no	0.072	0.070	EPSD	COSMIC	0.010	Down-regulation
Other_Aur_AurB_ST	Q3KR16	PLEKHG6	Q96GD4	AURKB	S537	R531W	531	Missense	distal	-6	no	0.072	0.070	EPSD	COSMIC	0.010	Down-regulation
Other_Aur_AurB_ST	Q3KR16	PLEKHG6	Q96GD4	AURKB	S603	T599K	599	Missense	distal	-4	no	0.010	0.011	EPSD	COSMIC	0.010	Up-regulation
Other_Aur_AurB_ST	Q3KR16	PLEKHG6	Q96GD4	AURKB	T620	R627W	627	Missense	distal	7	no	0.068	0.067	EPSD;PhosphoSitePlus	COSMIC;CCLE	0.010	Down-regulation
Other_Aur_AurB_ST	Q3KR16	PLEKHG6	Q96GD4	AURKB	T620	T620I	620	Missense	central	0	yes	0.068	0.000	EPSD;PhosphoSitePlus	COSMIC	0.010	Loss
Other_Aur_AurB_ST	Q3KR16	PLEKHG6	Q96GD4	AURKB	T620	R627Q	627	Missense	distal	7	no	0.068	0.067	EPSD;PhosphoSitePlus	COSMIC	0.010	Down-regulation
Other_Aur_AurB_ST	Q3KR16	PLEKHG6	Q96GD4	AURKB	T620	R615Q	615	Missense	distal	-5	no	0.068	0.066	EPSD;PhosphoSitePlus	COSMIC;CCLE	0.010	Down-regulation
Other_Aur_AurB_ST	Q96GD4	AURKB	Q96GD4	AURKB	S331	W326R	326	Missense	distal	-5	no	0.012	0.014	EPSD	COSMIC	0.010	Up-regulation
Other_Aur_AurB_ST	Q96GD4	AURKB	Q96GD4	AURKB	S331	R328Q	328	Missense	distal	-3	no	0.012	0.005	EPSD	COSMIC	0.010	Loss
Other_Aur_AurB_ST	Q96GD4	AURKB	Q96GD4	AURKB	S331	A329V	329	Missense	proximal	-2	no	0.012	0.007	EPSD	COSMIC	0.010	Loss
Other_Aur_AurB_ST	Q96GD4	AURKB	Q96GD4	AURKB	S331	R328W	328	Missense	distal	-3	no	0.012	0.006	EPSD	COSMIC	0.010	Loss
Other_Aur_AurB_ST	P17661	DES	Q96GD4	AURKB	S45	G41S	41	Missense	distal	-4	no	0.010	0.011	EPSD	COSMIC	0.010	Up-regulation
Other_Aur_AurB_ST	P17661	DES	Q96GD4	AURKB	S60	S60L	60	Missense	central	0	yes	0.075	0.000	EPSD;PhosphoSitePlus	COSMIC	0.010	Loss
Other_Aur_AurB_ST	P17661	DES	Q96GD4	AURKB	S60	G64R	64	Missense	distal	4	no	0.075	0.076	EPSD;PhosphoSitePlus	COSMIC;CCLE	0.010	Up-regulation
Other_Aur_AurB_ST	P17661	DES	Q96GD4	AURKB	T431	R429Q	429	Missense	proximal	-2	no	0.069	-0.005	EPSD	COSMIC	0.010	Loss
Other_Aur_AurB_ST	P17661	DES	Q96GD4	AURKB	T431	A425T	425	Missense	distal	-6	no	0.069	0.068	EPSD	COSMIC	0.010	Down-regulation
Other_Aur_AurB_ST	P35659	DEK	Q96GD4	AURKB	T199	K202R	202	Missense	distal	3	no	0.010	0.009	EPSD	COSMIC	0.010	Loss
Other_Aur_AurB_ST	P35659	DEK	Q96GD4	AURKB	S204	K202R	202	Missense	proximal	-2	no	0.016	0.075	EPSD	COSMIC	0.010	Up-regulation
Other_Aur_AurB_ST	P35659	DEK	Q96GD4	AURKB	T220	E224K	224	Missense	distal	4	no	0.019	0.020	EPSD	COSMIC	0.010	Up-regulation
Other_Aur_AurB_ST	P35659	DEK	Q96GD4	AURKB	S251	K249E	249	Missense	proximal	-2	no	0.012	-0.001	EPSD	COSMIC	0.010	Loss
Other_Aur_AurB_ST	P35659	DEK	Q96GD4	AURKB	T328	E327K	327	Missense	proximal	-1	no	0.008	0.010	EPSD	COSMIC	0.010	Gain
Other_Aur_AurB_ST	P35659	DEK	Q96GD4	AURKB	T369	T369P	369	Missense	central	0	yes	0.010	0.000	EPSD	COSMIC	0.010	Loss
Other_Aur_AurB_ST	P05787	KRT8	Q96GD4	AURKB	S34	S31A	31	Missense	distal	-3	no	0.072	0.073	EPSD	COSMIC	0.010	Up-regulation
Other_Aur_AurB_ST	P05787	KRT8	Q96GD4	AURKB	S134	T131M	131	Missense	distal	-3	no	0.011	0.010	EPSD	COSMIC	0.010	Down-regulation
Other_Aur_AurB_ST	P05787	KRT8	Q96GD4	AURKB	S134	M139K	139	Missense	distal	5	no	0.011	0.010	EPSD	COSMIC	0.010	Down-regulation
Other_Aur_AurB_ST	P05787	KRT8	Q96GD4	AURKB	T303	R301C	301	Missense	proximal	-2	no	0.075	0.004	EPSD	COSMIC	0.010	Loss
Other_Aur_AurB_ST	P05787	KRT8	Q96GD4	AURKB	T303	R302H	302	Missense	proximal	-1	no	0.075	0.067	EPSD	COSMIC	0.010	Down-regulation
Other_Aur_AurB_ST	P05787	KRT8	Q96GD4	AURKB	T303	G297R	297	Missense	distal	-6	no	0.075	0.076	EPSD	COSMIC	0.010	Up-regulation
Other_Aur_AurB_ST	P05787	KRT8	Q96GD4	AURKB	T303	R302C	302	Missense	proximal	-1	no	0.075	0.067	EPSD	COSMIC;GDSC	0.010	Down-regulation
Other_Aur_AurB_ST	P05787	KRT8	Q96GD4	AURKB	T303	R301Q	301	Missense	proximal	-2	no	0.075	0.001	EPSD	COSMIC	0.010	Loss
Other_Aur_AurB_ST	P05787	KRT8	Q96GD4	AURKB	S330	S330F	330	Missense	central	0	yes	0.073	0.000	EPSD	COSMIC	0.010	Loss
Other_Aur_AurB_ST	P05787	KRT8	Q96GD4	AURKB	S330	R328G	328	Missense	proximal	-2	no	0.073	0.001	EPSD	COSMIC	0.010	Loss
Other_Aur_AurB_ST	P05787	KRT8	Q96GD4	AURKB	S354	L353S	353	Missense	proximal	-1	no	0.013	0.014	EPSD	COSMIC	0.010	Up-regulation
Other_Aur_AurB_ST	P05787	KRT8	Q96GD4	AURKB	S354	A359T	359	Missense	distal	5	no	0.013	0.014	EPSD	COSMIC	0.010	Up-regulation
Other_Aur_AurB_ST	P05787	KRT8	Q96GD4	AURKB	S354	S354Y	354	Missense	central	0	yes	0.013	0.000	EPSD	COSMIC	0.010	Loss
Other_Aur_AurB_ST	P05787	KRT8	Q96GD4	AURKB	S354	N350S	350	Missense	distal	-4	no	0.013	0.014	EPSD	COSMIC	0.010	Up-regulation
Other_Aur_AurB_ST	P05787	KRT8	Q96GD4	AURKB	S354	S354F	354	Missense	central	0	yes	0.013	0.000	EPSD	COSMIC	0.010	Loss
Other_Aur_AurB_ST	P05787	KRT8	Q96GD4	AURKB	S400	E398K	398	Missense	proximal	-2	no	-0.003	0.010	EPSD	COSMIC	0.010	Gain
Other_Aur_AurB_ST	P05787	KRT8	Q96GD4	AURKB	S456	R454G	454	Missense	proximal	-2	no	0.073	0.001	EPSD	COSMIC	0.010	Loss
Other_Aur_AurB_ST	P05787	KRT8	Q96GD4	AURKB	S457	R454G	454	Missense	distal	-3	no	0.010	0.004	EPSD	COSMIC	0.010	Loss
Other_Aur_AurB_ST	P04637	TP53	Q96GD4	AURKB	S20	T18K	18	Missense	proximal	-2	no	0.004	0.012	EPSD	COSMIC	0.010	Gain
Other_Aur_AurB_ST	P04637	TP53	Q96GD4	AURKB	S20	T18R	18	Missense	proximal	-2	no	0.004	0.071	EPSD	COSMIC	0.010	Gain
Other_Aur_AurB_ST	P04637	TP53	Q96GD4	AURKB	S37	L35R	35	Missense	proximal	-2	no	-0.002	0.069	EPSD	COSMIC	0.010	Gain
Other_Aur_AurB_ST	P04637	TP53	Q96GD4	AURKB	S46	M44R	44	Missense	proximal	-2	no	0.002	0.073	EPSD	COSMIC	0.010	Gain
Other_Aur_AurB_ST	P04637	TP53	Q96GD4	AURKB	S127	T125K	125	Missense	proximal	-2	no	0.005	0.013	EPSD	COSMIC	0.010	Gain
Other_Aur_AurB_ST	P04637	TP53	Q96GD4	AURKB	S183	G187V	187	Missense	distal	4	no	0.073	0.072	EPSD;PhosphoSitePlus	COSMIC	0.010	Down-regulation
Other_Aur_AurB_ST	P04637	TP53	Q96GD4	AURKB	S183	S183C	183	Missense	central	0	yes	0.073	0.000	EPSD;PhosphoSitePlus	COSMIC	0.010	Loss
Other_Aur_AurB_ST	P04637	TP53	Q96GD4	AURKB	S183	S183P	183	Missense	central	0	yes	0.073	0.000	EPSD;PhosphoSitePlus	COSMIC	0.010	Loss
Other_Aur_AurB_ST	P04637	TP53	Q96GD4	AURKB	S183	S185G	185	Missense	proximal	2	no	0.073	0.072	EPSD;PhosphoSitePlus	COSMIC	0.010	Down-regulation
Other_Aur_AurB_ST	P04637	TP53	Q96GD4	AURKB	S183	S183L	183	Missense	central	0	yes	0.073	0.000	EPSD;PhosphoSitePlus	COSMIC	0.010	Loss
Other_Aur_AurB_ST	P04637	TP53	Q96GD4	AURKB	S183	R181L	181	Missense	proximal	-2	no	0.073	0.002	EPSD;PhosphoSitePlus	COSMIC	0.010	Loss
Other_Aur_AurB_ST	P04637	TP53	Q96GD4	AURKB	S183	H178P	178	Missense	distal	-5	no	0.073	0.072	EPSD;PhosphoSitePlus	COSMIC	0.010	Down-regulation
Other_Aur_AurB_ST	P04637	TP53	Q96GD4	AURKB	S183	D186N	186	Missense	distal	3	no	0.073	0.072	EPSD;PhosphoSitePlus	COSMIC	0.010	Down-regulation
Other_Aur_AurB_ST	P04637	TP53	Q96GD4	AURKB	S183	H178L	178	Missense	distal	-5	no	0.073	0.072	EPSD;PhosphoSitePlus	COSMIC	0.010	Down-regulation
Other_Aur_AurB_ST	P04637	TP53	Q96GD4	AURKB	S183	L188V	188	Missense	distal	5	no	0.073	0.072	EPSD;PhosphoSitePlus	COSMIC	0.010	Down-regulation
Other_Aur_AurB_ST	P04637	TP53	Q96GD4	AURKB	S183	A189V	189	Missense	distal	6	no	0.073	0.072	EPSD;PhosphoSitePlus	COSMIC	0.010	Down-regulation
Other_Aur_AurB_ST	P04637	TP53	Q96GD4	AURKB	S183	H178Y	178	Missense	distal	-5	no	0.073	0.072	EPSD;PhosphoSitePlus	COSMIC	0.010	Down-regulation
Other_Aur_AurB_ST	P04637	TP53	Q96GD4	AURKB	S183	D186H	186	Missense	distal	3	no	0.073	0.072	EPSD;PhosphoSitePlus	COSMIC	0.010	Down-regulation
Other_Aur_AurB_ST	P04637	TP53	Q96GD4	AURKB	S183	L188Q	188	Missense	distal	5	no	0.073	0.072	EPSD;PhosphoSitePlus	COSMIC	0.010	Down-regulation
Other_Aur_AurB_ST	P04637	TP53	Q96GD4	AURKB	S183	H178N	178	Missense	distal	-5	no	0.073	0.072	EPSD;PhosphoSitePlus	COSMIC	0.010	Down-regulation
Other_Aur_AurB_ST	P04637	TP53	Q96GD4	AURKB	S183	G187R	187	Missense	distal	4	no	0.073	0.074	EPSD;PhosphoSitePlus	COSMIC;GDSC	0.010	Up-regulation
Other_Aur_AurB_ST	P04637	TP53	Q96GD4	AURKB	S183	S185T	185	Missense	proximal	2	no	0.073	0.072	EPSD;PhosphoSitePlus	COSMIC	0.010	Down-regulation
Other_Aur_AurB_ST	P04637	TP53	Q96GD4	AURKB	S183	S185N	185	Missense	proximal	2	no	0.073	0.072	EPSD;PhosphoSitePlus	COSMIC	0.010	Down-regulation
Other_Aur_AurB_ST	P04637	TP53	Q96GD4	AURKB	S183	S185C	185	Missense	proximal	2	no	0.073	0.072	EPSD;PhosphoSitePlus	COSMIC	0.010	Down-regulation
Other_Aur_AurB_ST	P04637	TP53	Q96GD4	AURKB	S183	S185I	185	Missense	proximal	2	no	0.073	0.072	EPSD;PhosphoSitePlus	COSMIC	0.010	Down-regulation
Other_Aur_AurB_ST	P04637	TP53	Q96GD4	AURKB	S183	A189P	189	Missense	distal	6	no	0.073	0.072	EPSD;PhosphoSitePlus	COSMIC	0.010	Down-regulation
Other_Aur_AurB_ST	P04637	TP53	Q96GD4	AURKB	S183	E180Q	180	Missense	distal	-3	no	0.073	0.072	EPSD;PhosphoSitePlus	COSMIC	0.010	Down-regulation
Other_Aur_AurB_ST	P04637	TP53	Q96GD4	AURKB	S183	R181S	181	Missense	proximal	-2	no	0.073	0.000	EPSD;PhosphoSitePlus	COSMIC	0.010	Loss
Other_Aur_AurB_ST	P04637	TP53	Q96GD4	AURKB	S183	C182R	182	Missense	proximal	-1	no	0.073	0.080	EPSD;PhosphoSitePlus	COSMIC	0.010	Up-regulation
Other_Aur_AurB_ST	P04637	TP53	Q96GD4	AURKB	S183	E180G	180	Missense	distal	-3	no	0.073	0.072	EPSD;PhosphoSitePlus	COSMIC	0.010	Down-regulation
Other_Aur_AurB_ST	P04637	TP53	Q96GD4	AURKB	S183	L188M	188	Missense	distal	5	no	0.073	0.072	EPSD;PhosphoSitePlus	COSMIC	0.010	Down-regulation
Other_Aur_AurB_ST	P04637	TP53	Q96GD4	AURKB	S183	A189G	189	Missense	distal	6	no	0.073	0.072	EPSD;PhosphoSitePlus	COSMIC	0.010	Down-regulation
Other_Aur_AurB_ST	P04637	TP53	Q96GD4	AURKB	S183	R181G	181	Missense	proximal	-2	no	0.073	0.001	EPSD;PhosphoSitePlus	COSMIC	0.010	Loss
Other_Aur_AurB_ST	P04637	TP53	Q96GD4	AURKB	S183	D186X	186	Missense	distal	3	no	0.073	0.072	EPSD;PhosphoSitePlus	COSMIC	0.010	Down-regulation
Other_Aur_AurB_ST	P04637	TP53	Q96GD4	AURKB	S183	R181Y	181	Missense	proximal	-2	no	0.073	0.002	EPSD;PhosphoSitePlus	COSMIC	0.010	Loss
Other_Aur_AurB_ST	P04637	TP53	Q96GD4	AURKB	T211	R209Q	209	Missense	proximal	-2	no	0.069	-0.005	EPSD;PhosphoSitePlus	COSMIC	0.010	Loss
Other_Aur_AurB_ST	P04637	TP53	Q96GD4	AURKB	T211	R209W	209	Missense	proximal	-2	no	0.069	0.000	EPSD;PhosphoSitePlus	COSMIC	0.010	Loss
Other_Aur_AurB_ST	P04637	TP53	Q96GD4	AURKB	T211	R209P	209	Missense	proximal	-2	no	0.069	-0.005	EPSD;PhosphoSitePlus	COSMIC	0.010	Loss
Other_Aur_AurB_ST	P04637	TP53	Q96GD4	AURKB	T211	R209L	209	Missense	proximal	-2	no	0.069	-0.001	EPSD;PhosphoSitePlus	COSMIC	0.010	Loss
Other_Aur_AurB_ST	P04637	TP53	Q96GD4	AURKB	T211	R209G	209	Missense	proximal	-2	no	0.069	-0.003	EPSD;PhosphoSitePlus	COSMIC	0.010	Loss
Other_Aur_AurB_ST	P04637	TP53	Q96GD4	AURKB	T211	R209C	209	Missense	proximal	-2	no	0.069	-0.001	EPSD;PhosphoSitePlus	COSMIC	0.010	Loss
Other_Aur_AurB_ST	P04637	TP53	Q96GD4	AURKB	T211	T211N	211	Missense	central	0	yes	0.069	0.000	EPSD;PhosphoSitePlus	COSMIC	0.010	Loss
Other_Aur_AurB_ST	P04637	TP53	Q96GD4	AURKB	T211	R209T	209	Missense	proximal	-2	no	0.069	0.002	EPSD;PhosphoSitePlus	COSMIC	0.010	Loss
Other_Aur_AurB_ST	P04637	TP53	Q96GD4	AURKB	T211	D208Y	208	Missense	distal	-3	no	0.069	0.070	EPSD;PhosphoSitePlus	COSMIC	0.010	Up-regulation
Other_Aur_AurB_ST	P04637	TP53	Q96GD4	AURKB	T211	D208H	208	Missense	distal	-3	no	0.069	0.070	EPSD;PhosphoSitePlus	COSMIC	0.010	Up-regulation
Other_Aur_AurB_ST	P04637	TP53	Q96GD4	AURKB	T211	N210K	210	Missense	proximal	-1	no	0.069	0.071	EPSD;PhosphoSitePlus	COSMIC	0.010	Up-regulation
Other_Aur_AurB_ST	P04637	TP53	Q96GD4	AURKB	S215	R209Q	209	Missense	distal	-6	no	0.072	0.070	EPSD;PhosphoSitePlus	COSMIC	0.010	Down-regulation
Other_Aur_AurB_ST	P04637	TP53	Q96GD4	AURKB	S215	R209W	209	Missense	distal	-6	no	0.072	0.070	EPSD;PhosphoSitePlus	COSMIC	0.010	Down-regulation
Other_Aur_AurB_ST	P04637	TP53	Q96GD4	AURKB	S215	R209P	209	Missense	distal	-6	no	0.072	0.070	EPSD;PhosphoSitePlus	COSMIC	0.010	Down-regulation
Other_Aur_AurB_ST	P04637	TP53	Q96GD4	AURKB	S215	R209L	209	Missense	distal	-6	no	0.072	0.070	EPSD;PhosphoSitePlus	COSMIC	0.010	Down-regulation
Other_Aur_AurB_ST	P04637	TP53	Q96GD4	AURKB	S215	R209G	209	Missense	distal	-6	no	0.072	0.070	EPSD;PhosphoSitePlus	COSMIC	0.010	Down-regulation
Other_Aur_AurB_ST	P04637	TP53	Q96GD4	AURKB	S215	R209C	209	Missense	distal	-6	no	0.072	0.070	EPSD;PhosphoSitePlus	COSMIC	0.010	Down-regulation
Other_Aur_AurB_ST	P04637	TP53	Q96GD4	AURKB	S215	V216A	216	Missense	proximal	1	no	0.072	0.071	EPSD;PhosphoSitePlus	COSMIC	0.010	Down-regulation
Other_Aur_AurB_ST	P04637	TP53	Q96GD4	AURKB	S215	H214Q	214	Missense	proximal	-1	no	0.072	0.071	EPSD;PhosphoSitePlus	COSMIC	0.010	Down-regulation
Other_Aur_AurB_ST	P04637	TP53	Q96GD4	AURKB	S215	R213W	213	Missense	proximal	-2	no	0.072	0.002	EPSD;PhosphoSitePlus	COSMIC	0.010	Loss
Other_Aur_AurB_ST	P04637	TP53	Q96GD4	AURKB	S215	V218A	218	Missense	distal	3	no	0.072	0.071	EPSD;PhosphoSitePlus	COSMIC	0.010	Down-regulation
Other_Aur_AurB_ST	P04637	TP53	Q96GD4	AURKB	S215	S215C	215	Missense	central	0	yes	0.072	0.000	EPSD;PhosphoSitePlus	COSMIC;GDSC;CCLE	0.010	Loss
Other_Aur_AurB_ST	P04637	TP53	Q96GD4	AURKB	S215	R209T	209	Missense	distal	-6	no	0.072	0.070	EPSD;PhosphoSitePlus	COSMIC	0.010	Down-regulation
Other_Aur_AurB_ST	P04637	TP53	Q96GD4	AURKB	S215	P219R	219	Missense	distal	4	no	0.072	0.073	EPSD;PhosphoSitePlus	COSMIC	0.010	Up-regulation
Other_Aur_AurB_ST	P04637	TP53	Q96GD4	AURKB	S215	H214P	214	Missense	proximal	-1	no	0.072	0.071	EPSD;PhosphoSitePlus	COSMIC	0.010	Down-regulation
Other_Aur_AurB_ST	P04637	TP53	Q96GD4	AURKB	S269	S269N	269	Missense	central	0	yes	0.071	0.000	EPSD;PhosphoSitePlus	COSMIC	0.010	Loss
Other_Aur_AurB_ST	P04637	TP53	Q96GD4	AURKB	S269	V274I	274	Missense	distal	5	no	0.071	0.070	EPSD;PhosphoSitePlus	COSMIC	0.010	Down-regulation
Other_Aur_AurB_ST	P04637	TP53	Q96GD4	AURKB	S269	S269G	269	Missense	central	0	yes	0.071	0.000	EPSD;PhosphoSitePlus	COSMIC	0.010	Loss
Other_Aur_AurB_ST	P04637	TP53	Q96GD4	AURKB	S269	R273Q	273	Missense	distal	4	no	0.071	0.070	EPSD;PhosphoSitePlus	COSMIC	0.010	Down-regulation
Other_Aur_AurB_ST	P04637	TP53	Q96GD4	AURKB	S269	L264R	264	Missense	distal	-5	no	0.071	0.072	EPSD;PhosphoSitePlus	COSMIC;GDSC;CCLE	0.010	Up-regulation
Other_Aur_AurB_ST	P04637	TP53	Q96GD4	AURKB	S269	R273Y	273	Missense	distal	4	no	0.071	0.070	EPSD;PhosphoSitePlus	COSMIC;CCLE	0.010	Down-regulation
Other_Aur_AurB_ST	P04637	TP53	Q96GD4	AURKB	S269	S269C	269	Missense	central	0	yes	0.071	0.000	EPSD;PhosphoSitePlus	COSMIC	0.010	Loss
Other_Aur_AurB_ST	P04637	TP53	Q96GD4	AURKB	S269	N268K	268	Missense	proximal	-1	no	0.071	0.072	EPSD;PhosphoSitePlus	COSMIC	0.010	Up-regulation
Other_Aur_AurB_ST	P04637	TP53	Q96GD4	AURKB	S269	G266K	266	Missense	distal	-3	no	0.071	0.072	EPSD;PhosphoSitePlus	COSMIC	0.010	Up-regulation
Other_Aur_AurB_ST	P04637	TP53	Q96GD4	AURKB	S269	S269I	269	Missense	central	0	yes	0.071	0.000	EPSD;PhosphoSitePlus	COSMIC	0.010	Loss
Other_Aur_AurB_ST	P04637	TP53	Q96GD4	AURKB	S269	S269R	269	Missense	central	0	yes	0.071	0.000	EPSD;PhosphoSitePlus	COSMIC	0.010	Loss
Other_Aur_AurB_ST	P04637	TP53	Q96GD4	AURKB	S269	G262R	262	Missense	distal	-7	no	0.071	0.070	EPSD;PhosphoSitePlus	COSMIC	0.010	Down-regulation
Other_Aur_AurB_ST	P04637	TP53	Q96GD4	AURKB	S269	V272K	272	Missense	distal	3	no	0.071	0.070	EPSD;PhosphoSitePlus	COSMIC	0.010	Down-regulation
Other_Aur_AurB_ST	P04637	TP53	Q96GD4	AURKB	S269	N268F	268	Missense	proximal	-1	no	0.071	0.070	EPSD;PhosphoSitePlus	COSMIC	0.010	Down-regulation
Other_Aur_AurB_ST	P04637	TP53	Q96GD4	AURKB	T284	R283C	283	Missense	proximal	-1	no	0.077	0.070	PhosphoSitePlus;EPSD	COSMIC	0.010	Down-regulation
Other_Aur_AurB_ST	P04637	TP53	Q96GD4	AURKB	T284	T284A	284	Missense	central	0	yes	0.077	0.000	PhosphoSitePlus;EPSD	COSMIC	0.010	Loss
Other_Aur_AurB_ST	P04637	TP53	Q96GD4	AURKB	T284	K291R	291	Missense	distal	7	no	0.077	0.078	PhosphoSitePlus;EPSD	COSMIC	0.010	Up-regulation
Other_Aur_AurB_ST	P04637	TP53	Q96GD4	AURKB	T284	R283L	283	Missense	proximal	-1	no	0.077	0.070	PhosphoSitePlus;EPSD	COSMIC	0.010	Down-regulation
Other_Aur_AurB_ST	P04637	TP53	Q96GD4	AURKB	T284	L289R	289	Missense	distal	5	no	0.077	0.075	PhosphoSitePlus;EPSD	COSMIC	0.010	Down-regulation
Other_Aur_AurB_ST	P04637	TP53	Q96GD4	AURKB	T284	T284I	284	Missense	central	0	yes	0.077	0.000	PhosphoSitePlus;EPSD	COSMIC	0.010	Loss
Other_Aur_AurB_ST	P04637	TP53	Q96GD4	AURKB	T284	R282L	282	Missense	proximal	-2	no	0.077	0.007	PhosphoSitePlus;EPSD	COSMIC	0.010	Loss
Other_Aur_AurB_ST	P04637	TP53	Q96GD4	AURKB	T284	D281R	281	Missense	distal	-3	no	0.077	0.084	PhosphoSitePlus;EPSD	COSMIC	0.010	Up-regulation
Other_Aur_AurB_ST	P04637	TP53	Q96GD4	AURKB	T284	R282H	282	Missense	proximal	-2	no	0.077	0.007	PhosphoSitePlus;EPSD	COSMIC	0.010	Loss
Other_Aur_AurB_ST	P04637	TP53	Q96GD4	AURKB	T284	N288K	288	Missense	distal	4	no	0.077	0.078	PhosphoSitePlus;EPSD	COSMIC	0.010	Up-regulation
Other_Aur_AurB_ST	P04637	TP53	Q96GD4	AURKB	T284	R283G	283	Missense	proximal	-1	no	0.077	0.070	PhosphoSitePlus;EPSD	COSMIC	0.010	Down-regulation
Other_Aur_AurB_ST	P04637	TP53	Q96GD4	AURKB	T284	G279A	279	Missense	distal	-5	no	0.077	0.078	PhosphoSitePlus;EPSD	COSMIC	0.010	Up-regulation
Other_Aur_AurB_ST	P04637	TP53	Q96GD4	AURKB	T304	G302R	302	Missense	proximal	-2	no	-0.004	0.068	EPSD	COSMIC	0.010	Gain
Other_Aur_AurB_ST	P04637	TP53	Q96GD4	AURKB	S313	N311K	311	Missense	proximal	-2	no	-0.001	0.011	EPSD	COSMIC	0.010	Gain
Other_Aur_AurB_ST	P04637	TP53	Q96GD4	AURKB	S366	K370N	370	Missense	distal	4	no	0.010	0.009	EPSD	COSMIC	0.010	Loss
Other_Aur_AurB_ST	P04637	TP53	Q96GD4	AURKB	S366	A364D	364	Missense	proximal	-2	no	0.010	0.004	EPSD	COSMIC	0.010	Loss
Other_Aur_AurB_ST	P04637	TP53	Q96GD4	AURKB	S366	S366A	366	Missense	central	0	yes	0.010	0.000	EPSD	COSMIC	0.010	Loss
Other_Aur_AurB_ST	P04637	TP53	Q96GD4	AURKB	S366	G361R	361	Missense	distal	-5	no	0.010	0.011	EPSD	COSMIC	0.010	Up-regulation
Other_Aur_AurB_ST	P04637	TP53	Q96GD4	AURKB	S366	K370Q	370	Missense	distal	4	no	0.010	0.009	EPSD	COSMIC	0.010	Loss
Other_Aur_AurB_ST	Q9BQG0	MYBBP1A	Q96GD4	AURKB	S672	A670T	670	Missense	proximal	-2	no	0.013	0.014	EPSD	COSMIC;CCLE	0.010	Up-regulation
Other_Aur_AurB_ST	Q9BQG0	MYBBP1A	Q96GD4	AURKB	S1241	R1240Q	1240	Missense	proximal	-1	no	0.010	0.002	EPSD	COSMIC	0.010	Loss
Other_Aur_AurB_ST	Q9BQG0	MYBBP1A	Q96GD4	AURKB	S1241	R1240W	1240	Missense	proximal	-1	no	0.010	0.003	EPSD	COSMIC	0.010	Loss
Other_Aur_AurB_ST	Q9BQG0	MYBBP1A	Q96GD4	AURKB	S1259	S1259P	1259	Missense	central	0	yes	0.013	0.000	EPSD	COSMIC	0.010	Loss
Other_Aur_AurB_ST	Q9BQG0	MYBBP1A	Q96GD4	AURKB	S1303	R1297Q	1297	Missense	distal	-6	no	0.073	0.072	PhosphoSitePlus	COSMIC	0.010	Down-regulation
Other_Aur_AurB_ST	Q8TF76	HASPIN	Q96GD4	AURKB	S93	S93I	93	Missense	central	0	yes	0.071	0.000	PhosphoSitePlus;EPSD	COSMIC	0.010	Loss
Other_Aur_AurB_ST	Q8TF76	HASPIN	Q96GD4	AURKB	S93	S93C	93	Missense	central	0	yes	0.071	0.000	PhosphoSitePlus;EPSD	COSMIC	0.010	Loss
Other_Aur_AurB_ST	Q8TF76	HASPIN	Q96GD4	AURKB	S93	S93R	93	Missense	central	0	yes	0.071	0.000	PhosphoSitePlus;EPSD	COSMIC	0.010	Loss
Other_Aur_AurB_ST	Q8TF76	HASPIN	Q96GD4	AURKB	T95	S93R	93	Missense	proximal	-2	no	-0.006	0.067	EPSD	COSMIC	0.010	Gain
Other_Aur_AurB_ST	Q8TF76	HASPIN	Q96GD4	AURKB	S216	S216Y	216	Missense	central	0	yes	0.070	0.000	EPSD	COSMIC	0.010	Loss
Other_Aur_AurB_ST	Q8TF76	HASPIN	Q96GD4	AURKB	S216	D213G	213	Missense	distal	-3	no	0.070	0.071	EPSD	COSMIC	0.010	Up-regulation
Other_Aur_AurB_ST	Q8TF76	HASPIN	Q96GD4	AURKB	S340	S340R	340	Missense	central	0	yes	0.074	0.000	EPSD	COSMIC	0.010	Loss
Other_Aur_AurB_ST	Q8TF76	HASPIN	Q96GD4	AURKB	S366	G363R	363	Missense	distal	-3	no	0.011	0.017	EPSD	COSMIC	0.010	Up-regulation
Other_Aur_AurB_ST	Q8TF76	HASPIN	Q96GD4	AURKB	S366	S366L	366	Missense	central	0	yes	0.011	0.000	EPSD	COSMIC	0.010	Loss
Other_Aur_AurB_ST	Q8TF76	HASPIN	Q96GD4	AURKB	S620	R616Q	616	Missense	distal	-4	no	0.011	0.010	EPSD	COSMIC	0.010	Down-regulation
Other_Aur_AurB_ST	Q9UBB4	ATXN10	Q96GD4	AURKB	S12	R10G	10	Missense	proximal	-2	no	0.072	0.000	PhosphoSitePlus	COSMIC	0.010	Loss
Other_Aur_AurB_ST	Q9H410	DSN1	Q96GD4	AURKB	S57	H54R	54	Missense	distal	-3	no	0.005	0.012	EPSD	COSMIC	0.010	Gain
Other_Aur_AurB_ST	Q9H410	DSN1	Q96GD4	AURKB	S95	R92K	92	Missense	distal	-3	no	0.077	0.071	EPSD	COSMIC	0.010	Down-regulation
Other_Aur_AurB_ST	Q9H410	DSN1	Q96GD4	AURKB	S95	R93T	93	Missense	proximal	-2	no	0.077	0.010	EPSD	COSMIC	0.010	Down-regulation
Other_Aur_AurB_ST	Q9H410	DSN1	Q96GD4	AURKB	S100	R97Q	97	Missense	distal	-3	no	0.079	0.072	EPSD;PhosphoSitePlus	COSMIC	0.010	Down-regulation
Other_Aur_AurB_ST	Q9H410	DSN1	Q96GD4	AURKB	S100	A99G	99	Missense	proximal	-1	no	0.079	0.078	EPSD;PhosphoSitePlus	COSMIC	0.010	Down-regulation
Other_Aur_AurB_ST	Q9H410	DSN1	Q96GD4	AURKB	S100	S100G	100	Missense	central	0	yes	0.079	0.000	EPSD;PhosphoSitePlus	COSMIC	0.010	Loss
Other_Aur_AurB_ST	Q9H410	DSN1	Q96GD4	AURKB	S109	R106W	106	Missense	distal	-3	no	0.080	0.073	PhosphoSitePlus;EPSD	COSMIC	0.010	Down-regulation
Other_Aur_AurB_ST	Q9H410	DSN1	Q96GD4	AURKB	S109	R106Q	106	Missense	distal	-3	no	0.080	0.073	PhosphoSitePlus;EPSD	COSMIC;CCLE	0.010	Down-regulation
Other_Aur_AurB_ST	Q9H410	DSN1	Q96GD4	AURKB	S109	R107Q	107	Missense	proximal	-2	no	0.080	0.006	PhosphoSitePlus;EPSD	COSMIC;GDSC;CCLE	0.010	Loss
Other_Aur_AurB_ST	Q9H410	DSN1	Q96GD4	AURKB	S109	S109G	109	Missense	central	0	yes	0.080	0.000	PhosphoSitePlus;EPSD	COSMIC	0.010	Loss
Other_Aur_AurB_ST	O95239	KIF4A	Q96GD4	AURKB	S508	R506K	506	Missense	proximal	-2	no	0.071	0.012	EPSD	COSMIC	0.010	Down-regulation
Other_Aur_AurB_ST	O95239	KIF4A	Q96GD4	AURKB	T799	R798H	798	Missense	proximal	-1	no	0.083	0.076	PhosphoSitePlus	COSMIC	0.010	Down-regulation
Other_Aur_AurB_ST	O95239	KIF4A	Q96GD4	AURKB	T799	R798Q	798	Missense	proximal	-1	no	0.083	0.075	PhosphoSitePlus	COSMIC	0.010	Down-regulation
Other_Aur_AurB_ST	O95239	KIF4A	Q96GD4	AURKB	S801	R806H	806	Missense	distal	5	no	0.012	0.014	EPSD	COSMIC	0.010	Up-regulation
Other_Aur_AurB_ST	O95239	KIF4A	Q96GD4	AURKB	S801	R798H	798	Missense	distal	-3	no	0.012	0.006	EPSD	COSMIC	0.010	Loss
Other_Aur_AurB_ST	O95239	KIF4A	Q96GD4	AURKB	S801	S801F	801	Missense	central	0	yes	0.012	0.000	EPSD	COSMIC	0.010	Loss
Other_Aur_AurB_ST	O95239	KIF4A	Q96GD4	AURKB	S801	R798Q	798	Missense	distal	-3	no	0.012	0.005	EPSD	COSMIC	0.010	Loss
Other_Aur_AurB_ST	O95239	KIF4A	Q96GD4	AURKB	T1010	L1006R	1006	Missense	distal	-4	no	0.011	0.012	EPSD	COSMIC;CCLE	0.010	Up-regulation
Other_Aur_AurB_ST	O95239	KIF4A	Q96GD4	AURKB	S1126	R1120C	1120	Missense	distal	-6	no	0.015	0.013	EPSD	COSMIC	0.010	Down-regulation
Other_Aur_AurB_ST	Q53SF7	COBLL1	Q96GD4	AURKB	T69	P62S	62	Missense	distal	-7	no	0.010	0.009	EPSD	COSMIC	0.010	Loss
Other_Aur_AurB_ST	Q53SF7	COBLL1	Q96GD4	AURKB	T69	S73L	73	Missense	distal	4	no	0.010	0.009	EPSD	COSMIC	0.010	Loss
Other_Aur_AurB_ST	Q53SF7	COBLL1	Q96GD4	AURKB	T177	P176S	176	Missense	proximal	-1	no	0.010	0.011	EPSD	COSMIC	0.010	Up-regulation
Other_Aur_AurB_ST	Q53SF7	COBLL1	Q96GD4	AURKB	S202	R200T	200	Missense	proximal	-2	no	0.074	0.006	EPSD	COSMIC	0.010	Loss
Other_Aur_AurB_ST	Q53SF7	COBLL1	Q96GD4	AURKB	S202	S206L	206	Missense	distal	4	no	0.074	0.073	EPSD	COSMIC	0.010	Down-regulation
Other_Aur_AurB_ST	Q53SF7	COBLL1	Q96GD4	AURKB	T307	R305H	305	Missense	proximal	-2	no	0.065	-0.005	EPSD	COSMIC	0.010	Loss
Other_Aur_AurB_ST	Q53SF7	COBLL1	Q96GD4	AURKB	S311	P317S	317	Missense	distal	6	no	0.010	0.011	EPSD	COSMIC;CCLE	0.010	Up-regulation
Other_Aur_AurB_ST	Q53SF7	COBLL1	Q96GD4	AURKB	S311	R305H	305	Missense	distal	-6	no	0.010	0.009	EPSD	COSMIC	0.010	Loss
Other_Aur_AurB_ST	Q53SF7	COBLL1	Q96GD4	AURKB	S311	S311F	311	Missense	central	0	yes	0.010	0.000	EPSD	COSMIC	0.010	Loss
Other_Aur_AurB_ST	Q53SF7	COBLL1	Q96GD4	AURKB	S382	G376R	376	Missense	distal	-6	no	0.014	0.015	EPSD	COSMIC	0.010	Up-regulation
Other_Aur_AurB_ST	Q53SF7	COBLL1	Q96GD4	AURKB	S515	N513K	513	Missense	proximal	-2	no	0.001	0.013	EPSD	COSMIC	0.010	Gain
Other_Aur_AurB_ST	Q53SF7	COBLL1	Q96GD4	AURKB	T618	T618K	618	Missense	central	0	yes	0.012	0.000	EPSD	COSMIC	0.010	Loss
Other_Aur_AurB_ST	Q53SF7	COBLL1	Q96GD4	AURKB	S671	Q669K	669	Missense	proximal	-2	no	-0.004	0.011	EPSD	COSMIC	0.010	Gain
Other_Aur_AurB_ST	Q53SF7	COBLL1	Q96GD4	AURKB	T683	Q681K	681	Missense	proximal	-2	no	-0.005	0.010	EPSD	COSMIC	0.010	Gain
Other_Aur_AurB_ST	Q53SF7	COBLL1	Q96GD4	AURKB	S710	Q708R	708	Missense	proximal	-2	no	-0.005	0.069	EPSD	COSMIC	0.010	Gain
Other_Aur_AurB_ST	Q53SF7	COBLL1	Q96GD4	AURKB	T909	T909I	909	Missense	central	0	yes	0.068	0.000	EPSD	COSMIC	0.010	Loss
Other_Aur_AurB_ST	Q53SF7	COBLL1	Q96GD4	AURKB	T909	K904T	904	Missense	distal	-5	no	0.068	0.067	EPSD	COSMIC	0.010	Down-regulation
Other_Aur_AurB_ST	Q53SF7	COBLL1	Q96GD4	AURKB	T909	G910D	910	Missense	proximal	1	no	0.068	0.067	EPSD	COSMIC	0.010	Down-regulation
Other_Aur_AurB_ST	Q53SF7	COBLL1	Q96GD4	AURKB	S993	L992R	992	Missense	proximal	-1	no	0.004	0.011	EPSD	COSMIC	0.010	Gain
Other_Aur_AurB_ST	Q53SF7	COBLL1	Q96GD4	AURKB	S1082	R1079H	1079	Missense	distal	-3	no	0.011	0.004	EPSD	COSMIC;CCLE	0.010	Loss
Other_Aur_AurB_ST	Q53SF7	COBLL1	Q96GD4	AURKB	S1082	E1081K	1081	Missense	proximal	-1	no	0.011	0.013	EPSD	COSMIC	0.010	Up-regulation
Other_Aur_AurB_ST	Q53SF7	COBLL1	Q96GD4	AURKB	S1082	R1079C	1079	Missense	distal	-3	no	0.011	0.004	EPSD	COSMIC	0.010	Loss
Other_Aur_AurB_ST	Q53SF7	COBLL1	Q96GD4	AURKB	S1082	S1082L	1082	Missense	central	0	yes	0.011	0.000	EPSD	COSMIC	0.010	Loss
Other_Aur_AurB_ST	Q53SF7	COBLL1	Q96GD4	AURKB	S1128	Q1126R	1126	Missense	proximal	-2	no	0.002	0.075	EPSD	COSMIC	0.010	Gain
Other_Aur_AurB_ST	Q53SF7	COBLL1	Q96GD4	AURKB	S1160	R1158Q	1158	Missense	proximal	-2	no	0.075	0.001	EPSD	COSMIC	0.010	Loss
Other_Aur_AurB_ST	Q53SF7	COBLL1	Q96GD4	AURKB	S1193	L1192R	1192	Missense	proximal	-1	no	0.071	0.079	EPSD	COSMIC	0.010	Up-regulation
Other_Aur_AurB_ST	Q53SF7	COBLL1	Q96GD4	AURKB	S1193	R1191K	1191	Missense	proximal	-2	no	0.071	0.012	EPSD	COSMIC	0.010	Down-regulation
Other_Aur_AurB_ST	Q8NEY8	PPHLN1	Q96GD4	AURKB	S54	R59K	59	Missense	distal	5	no	0.008	0.010	EPSD	COSMIC	0.010	Gain
Other_Aur_AurB_ST	Q8NEY8	PPHLN1	Q96GD4	AURKB	S73	R72Q	72	Missense	proximal	-1	no	0.079	0.072	EPSD	COSMIC	0.010	Down-regulation
Other_Aur_AurB_ST	Q8NEY8	PPHLN1	Q96GD4	AURKB	S73	R72L	72	Missense	proximal	-1	no	0.079	0.072	EPSD	COSMIC	0.010	Down-regulation
Other_Aur_AurB_ST	Q8NEY8	PPHLN1	Q96GD4	AURKB	S73	R72H	72	Missense	proximal	-1	no	0.079	0.072	EPSD	COSMIC	0.010	Down-regulation
Other_Aur_AurB_ST	Q8NEY8	PPHLN1	Q96GD4	AURKB	S110	S110C	110	Missense	central	0	yes	0.079	0.000	PhosphoSitePlus	COSMIC	0.010	Loss
Other_Aur_AurB_ST	Q8NEY8	PPHLN1	Q96GD4	AURKB	S121	R125K	125	Missense	distal	4	no	0.012	0.011	EPSD	COSMIC	0.010	Down-regulation
Other_Aur_AurB_ST	Q8NEY8	PPHLN1	Q96GD4	AURKB	S121	E119Q	119	Missense	proximal	-2	no	0.012	0.010	EPSD	COSMIC;GDSC;CCLE	0.010	Down-regulation
Other_Aur_AurB_ST	Q8NEY8	PPHLN1	Q96GD4	AURKB	S121	R120L	120	Missense	proximal	-1	no	0.012	0.004	EPSD	COSMIC	0.010	Loss
Other_Aur_AurB_ST	Q8NEY8	PPHLN1	Q96GD4	AURKB	S121	R125T	125	Missense	distal	4	no	0.012	0.011	EPSD	COSMIC	0.010	Down-regulation
Other_Aur_AurB_ST	Q8NEY8	PPHLN1	Q96GD4	AURKB	S121	S121Y	121	Missense	central	0	yes	0.012	0.000	EPSD	COSMIC	0.010	Loss
Other_Aur_AurB_ST	Q8NEY8	PPHLN1	Q96GD4	AURKB	S159	R158M	158	Missense	proximal	-1	no	0.011	0.003	EPSD	COSMIC	0.010	Loss
Other_Aur_AurB_ST	Q8NEY8	PPHLN1	Q96GD4	AURKB	S159	S153L	153	Missense	distal	-6	no	0.011	0.010	EPSD	COSMIC	0.010	Down-regulation
Other_Aur_AurB_ST	Q8NEY8	PPHLN1	Q96GD4	AURKB	S167	H165R	165	Missense	proximal	-2	no	-0.003	0.068	EPSD	COSMIC	0.010	Gain
Other_Aur_AurB_ST	Q8NEY8	PPHLN1	Q96GD4	AURKB	S172	Q166L	166	Missense	distal	-6	no	0.070	0.069	EPSD	COSMIC;GDSC	0.010	Down-regulation
Other_Aur_AurB_ST	Q8NEY8	PPHLN1	Q96GD4	AURKB	S172	R170S	170	Missense	proximal	-2	no	0.070	-0.003	EPSD	COSMIC	0.010	Loss
Other_Aur_AurB_ST	Q8NEY8	PPHLN1	Q96GD4	AURKB	S172	H165R	165	Missense	distal	-7	no	0.070	0.069	EPSD	COSMIC	0.010	Down-regulation
Other_Aur_AurB_ST	Q8NEY8	PPHLN1	Q96GD4	AURKB	S222	D219N	219	Missense	distal	-3	no	0.009	0.010	EPSD	COSMIC	0.010	Gain
Other_Aur_AurB_ST	Q8NEY8	PPHLN1	Q96GD4	AURKB	S222	P221L	221	Missense	proximal	-1	no	0.009	0.010	EPSD	COSMIC	0.010	Gain
Other_Aur_AurB_ST	Q8NEY8	PPHLN1	Q96GD4	AURKB	S222	K227N	227	Missense	distal	5	no	0.009	0.010	EPSD	COSMIC	0.010	Gain
Other_Aur_AurB_ST	Q8NEY8	PPHLN1	Q96GD4	AURKB	T225	K220N	220	Missense	distal	-5	no	0.070	0.069	EPSD	COSMIC	0.010	Down-regulation
Other_Aur_AurB_ST	Q8NEY8	PPHLN1	Q96GD4	AURKB	T396	R395Q	395	Missense	proximal	-1	no	0.076	0.068	EPSD	COSMIC	0.010	Down-regulation
Other_Aur_AurB_ST	Q8NEY8	PPHLN1	Q96GD4	AURKB	T396	R394H	394	Missense	proximal	-2	no	0.076	0.005	EPSD	COSMIC;GDSC	0.010	Loss
Other_Aur_AurB_ST	Q8NEY8	PPHLN1	Q96GD4	AURKB	T396	R394S	394	Missense	proximal	-2	no	0.076	0.003	EPSD	COSMIC	0.010	Loss
Other_Aur_AurB_ST	Q8NEY8	PPHLN1	Q96GD4	AURKB	T397	R395Q	395	Missense	proximal	-2	no	0.080	0.006	EPSD	COSMIC	0.010	Loss
Other_Aur_AurB_ST	Q8NEY8	PPHLN1	Q96GD4	AURKB	T397	R394H	394	Missense	distal	-3	no	0.080	0.073	EPSD	COSMIC;GDSC	0.010	Down-regulation
Other_Aur_AurB_ST	Q8NEY8	PPHLN1	Q96GD4	AURKB	T397	R394S	394	Missense	distal	-3	no	0.080	0.073	EPSD	COSMIC	0.010	Down-regulation
Other_Aur_AurB_ST	Q5UIP0	RIF1	Q96GD4	AURKB	S111	R116H	116	Missense	distal	5	no	0.010	0.012	EPSD	COSMIC	0.010	Up-regulation
Other_Aur_AurB_ST	Q5UIP0	RIF1	Q96GD4	AURKB	S787	R785T	785	Missense	proximal	-2	no	0.070	0.003	EPSD	COSMIC;GDSC;CCLE	0.010	Loss
Other_Aur_AurB_ST	Q5UIP0	RIF1	Q96GD4	AURKB	S1162	K1160N	1160	Missense	proximal	-2	no	0.014	0.002	EPSD	COSMIC	0.010	Loss
Other_Aur_AurB_ST	Q5UIP0	RIF1	Q96GD4	AURKB	T1183	S1179L	1179	Missense	distal	-4	no	0.070	0.069	EPSD	COSMIC	0.010	Down-regulation
Other_Aur_AurB_ST	Q5UIP0	RIF1	Q96GD4	AURKB	T1183	R1181W	1181	Missense	proximal	-2	no	0.070	0.000	EPSD	COSMIC	0.010	Loss
Other_Aur_AurB_ST	Q5UIP0	RIF1	Q96GD4	AURKB	S1184	S1184L	1184	Missense	central	0	yes	0.020	0.000	EPSD	COSMIC	0.010	Loss
Other_Aur_AurB_ST	Q5UIP0	RIF1	Q96GD4	AURKB	S1184	R1181W	1181	Missense	distal	-3	no	0.020	0.014	EPSD	COSMIC	0.010	Down-regulation
Other_Aur_AurB_ST	Q5UIP0	RIF1	Q96GD4	AURKB	T1297	E1295K	1295	Missense	proximal	-2	no	-0.002	0.011	EPSD	COSMIC	0.010	Gain
Other_Aur_AurB_ST	Q5UIP0	RIF1	Q96GD4	AURKB	S1417	R1416Q	1416	Missense	proximal	-1	no	0.074	0.067	EPSD	COSMIC;CCLE	0.010	Down-regulation
Other_Aur_AurB_ST	Q5UIP0	RIF1	Q96GD4	AURKB	S1417	R1416P	1416	Missense	proximal	-1	no	0.074	0.066	EPSD	COSMIC	0.010	Down-regulation
Other_Aur_AurB_ST	Q5UIP0	RIF1	Q96GD4	AURKB	S1418	R1416Q	1416	Missense	proximal	-2	no	0.074	0.001	EPSD	COSMIC;CCLE	0.010	Loss
Other_Aur_AurB_ST	Q5UIP0	RIF1	Q96GD4	AURKB	S1418	R1416P	1416	Missense	proximal	-2	no	0.074	0.000	EPSD	COSMIC	0.010	Loss
Other_Aur_AurB_ST	Q5UIP0	RIF1	Q96GD4	AURKB	S1422	R1416Q	1416	Missense	distal	-6	no	0.086	0.084	EPSD	COSMIC;CCLE	0.010	Down-regulation
Other_Aur_AurB_ST	Q5UIP0	RIF1	Q96GD4	AURKB	S1422	R1416P	1416	Missense	distal	-6	no	0.086	0.084	EPSD	COSMIC	0.010	Down-regulation
Other_Aur_AurB_ST	Q5UIP0	RIF1	Q96GD4	AURKB	S1576	N1574K	1574	Missense	proximal	-2	no	0.004	0.016	EPSD	COSMIC	0.010	Gain
Other_Aur_AurB_ST	Q5UIP0	RIF1	Q96GD4	AURKB	S2189	E2191K	2191	Missense	proximal	2	no	0.021	0.022	EPSD	COSMIC	0.010	Up-regulation
Other_Aur_AurB_ST	Q5UIP0	RIF1	Q96GD4	AURKB	T2252	H2250R	2250	Missense	proximal	-2	no	0.000	0.071	EPSD	COSMIC	0.010	Gain
Other_Aur_AurB_ST	Q5UIP0	RIF1	Q96GD4	AURKB	S2352	R2347H	2347	Missense	distal	-5	no	0.014	0.012	EPSD	COSMIC	0.010	Down-regulation
Other_Aur_AurB_ST	Q5UIP0	RIF1	Q96GD4	AURKB	S2465	R2462H	2462	Missense	distal	-3	no	0.017	0.010	EPSD	COSMIC	0.010	Down-regulation
Other_Aur_AurB_ST	Q5UIP0	RIF1	Q96GD4	AURKB	S2465	S2471T	2471	Missense	distal	6	no	0.017	0.016	EPSD	COSMIC	0.010	Down-regulation
Other_Aur_AurB_ST	P05204	HMGN2	Q96GD4	AURKB	S25	E20K	20	Missense	distal	-5	no	0.078	0.079	PhosphoSitePlus;EPSD	COSMIC;GDSC;CCLE	0.010	Up-regulation
Other_Aur_AurB_ST	P05204	HMGN2	Q96GD4	AURKB	S29	P34S	34	Missense	distal	5	no	0.077	0.076	EPSD;PhosphoSitePlus	COSMIC	0.010	Down-regulation
Other_Aur_AurB_ST	Q08J23	NSUN2	Q96GD4	AURKB	T81	L74R	74	Missense	distal	-7	no	0.069	0.068	EPSD	COSMIC	0.010	Down-regulation
Other_Aur_AurB_ST	Q08J23	NSUN2	Q96GD4	AURKB	T81	R79G	79	Missense	proximal	-2	no	0.069	-0.003	EPSD	COSMIC	0.010	Loss
Other_Aur_AurB_ST	Q8TEW0	PARD3	Q96GD4	AURKB	S143	R142H	142	Missense	proximal	-1	no	0.078	0.070	EPSD	COSMIC	0.010	Down-regulation
Other_Aur_AurB_ST	Q8TEW0	PARD3	Q96GD4	AURKB	S144	R142H	142	Missense	proximal	-2	no	0.076	0.005	EPSD	COSMIC	0.010	Loss
Other_Aur_AurB_ST	Q8TEW0	PARD3	Q96GD4	AURKB	S174	G178R	178	Missense	distal	4	no	0.072	0.073	EPSD	COSMIC	0.010	Up-regulation
Other_Aur_AurB_ST	Q8TEW0	PARD3	Q96GD4	AURKB	S220	R215K	215	Missense	distal	-5	no	0.013	0.011	EPSD	COSMIC;GDSC;CCLE	0.010	Down-regulation
Other_Aur_AurB_ST	Q8TEW0	PARD3	Q96GD4	AURKB	S220	R219H	219	Missense	proximal	-1	no	0.013	0.005	EPSD	COSMIC	0.010	Loss
Other_Aur_AurB_ST	Q8TEW0	PARD3	Q96GD4	AURKB	S220	N217K	217	Missense	distal	-3	no	0.013	0.014	EPSD	COSMIC	0.010	Up-regulation
Other_Aur_AurB_ST	Q8TEW0	PARD3	Q96GD4	AURKB	S221	R215K	215	Missense	distal	-6	no	0.068	0.067	EPSD	COSMIC;GDSC;CCLE	0.010	Down-regulation
Other_Aur_AurB_ST	Q8TEW0	PARD3	Q96GD4	AURKB	S221	R219H	219	Missense	proximal	-2	no	0.068	-0.002	EPSD	COSMIC	0.010	Loss
Other_Aur_AurB_ST	Q8TEW0	PARD3	Q96GD4	AURKB	S221	N217K	217	Missense	distal	-4	no	0.068	0.069	EPSD	COSMIC	0.010	Up-regulation
Other_Aur_AurB_ST	Q8TEW0	PARD3	Q96GD4	AURKB	S561	E559K	559	Missense	proximal	-2	no	-0.003	0.010	EPSD	COSMIC	0.010	Gain
Other_Aur_AurB_ST	Q8TEW0	PARD3	Q96GD4	AURKB	S665	G670S	670	Missense	distal	5	no	0.077	0.076	EPSD	COSMIC	0.010	Down-regulation
Other_Aur_AurB_ST	Q8TEW0	PARD3	Q96GD4	AURKB	S685	R682K	682	Missense	distal	-3	no	0.072	0.067	EPSD	COSMIC	0.010	Down-regulation
Other_Aur_AurB_ST	Q8TEW0	PARD3	Q96GD4	AURKB	S685	R683K	683	Missense	proximal	-2	no	0.072	0.013	EPSD	COSMIC	0.010	Down-regulation
Other_Aur_AurB_ST	Q8TEW0	PARD3	Q96GD4	AURKB	S827	R832C	832	Missense	distal	5	no	0.068	0.070	EPSD	COSMIC	0.010	Up-regulation
Other_Aur_AurB_ST	Q8TEW0	PARD3	Q96GD4	AURKB	T833	R832C	832	Missense	proximal	-1	no	0.021	0.014	EPSD	COSMIC	0.010	Down-regulation
Other_Aur_AurB_ST	Q8TEW0	PARD3	Q96GD4	AURKB	T833	T833A	833	Missense	central	0	yes	0.021	0.000	EPSD	COSMIC	0.010	Loss
Other_Aur_AurB_ST	Q8TEW0	PARD3	Q96GD4	AURKB	S850	T847K	847	Missense	distal	-3	no	0.070	0.071	EPSD	COSMIC	0.010	Up-regulation
Other_Aur_AurB_ST	Q8TEW0	PARD3	Q96GD4	AURKB	S887	K885Q	885	Missense	proximal	-2	no	0.013	-0.002	EPSD	COSMIC	0.010	Loss
Other_Aur_AurB_ST	Q8TEW0	PARD3	Q96GD4	AURKB	S887	S887F	887	Missense	central	0	yes	0.013	0.000	EPSD	COSMIC	0.010	Loss
Other_Aur_AurB_ST	Q8TEW0	PARD3	Q96GD4	AURKB	S888	K885Q	885	Missense	distal	-3	no	0.011	0.009	EPSD	COSMIC	0.010	Loss
Other_Aur_AurB_ST	Q8TEW0	PARD3	Q96GD4	AURKB	S888	S892G	892	Missense	distal	4	no	0.011	0.010	EPSD	COSMIC	0.010	Down-regulation
Other_Aur_AurB_ST	Q8TEW0	PARD3	Q96GD4	AURKB	S888	S887F	887	Missense	proximal	-1	no	0.011	0.010	EPSD	COSMIC	0.010	Down-regulation
Other_Aur_AurB_ST	Q8TEW0	PARD3	Q96GD4	AURKB	S962	S962F	962	Missense	central	0	yes	0.071	0.000	PhosphoSitePlus	COSMIC	0.010	Loss
Other_Aur_AurB_ST	Q8TEW0	PARD3	Q96GD4	AURKB	S962	E961K	961	Missense	proximal	-1	no	0.071	0.073	PhosphoSitePlus	COSMIC	0.010	Up-regulation
Other_Aur_AurB_ST	Q8TEW0	PARD3	Q96GD4	AURKB	S1102	G1100R	1100	Missense	proximal	-2	no	-0.001	0.070	EPSD	COSMIC	0.010	Gain
Other_Aur_AurB_ST	Q8TEW0	PARD3	Q96GD4	AURKB	S1136	S1136F	1136	Missense	central	0	yes	0.071	0.000	EPSD	COSMIC	0.010	Loss
Other_Aur_AurB_ST	Q8TEW0	PARD3	Q96GD4	AURKB	S1136	V1141I	1141	Missense	distal	5	no	0.071	0.070	EPSD	COSMIC	0.010	Down-regulation
Other_Aur_AurB_ST	Q8TEW0	PARD3	Q96GD4	AURKB	T1176	R1174C	1174	Missense	proximal	-2	no	0.085	0.015	EPSD	COSMIC	0.010	Down-regulation
Other_Aur_AurB_ST	Q8TEW0	PARD3	Q96GD4	AURKB	T1176	R1173H	1173	Missense	distal	-3	no	0.085	0.079	EPSD	COSMIC	0.010	Down-regulation
Other_Aur_AurB_ST	Q8TEW0	PARD3	Q96GD4	AURKB	T1176	R1175Q	1175	Missense	proximal	-1	no	0.085	0.077	EPSD	COSMIC	0.010	Down-regulation
Other_Aur_AurB_ST	Q8TEW0	PARD3	Q96GD4	AURKB	T1176	R1174Q	1174	Missense	proximal	-2	no	0.085	0.011	EPSD	COSMIC	0.010	Down-regulation
Other_Aur_AurB_ST	Q8TEW0	PARD3	Q96GD4	AURKB	S1178	R1174C	1174	Missense	distal	-4	no	0.012	0.011	EPSD	COSMIC	0.010	Down-regulation
Other_Aur_AurB_ST	Q8TEW0	PARD3	Q96GD4	AURKB	S1178	R1173H	1173	Missense	distal	-5	no	0.012	0.010	EPSD	COSMIC	0.010	Down-regulation
Other_Aur_AurB_ST	Q8TEW0	PARD3	Q96GD4	AURKB	S1178	R1175Q	1175	Missense	distal	-3	no	0.012	0.005	EPSD	COSMIC	0.010	Loss
Other_Aur_AurB_ST	Q8TEW0	PARD3	Q96GD4	AURKB	S1178	R1174Q	1174	Missense	distal	-4	no	0.012	0.011	EPSD	COSMIC	0.010	Down-regulation
Other_Aur_AurB_ST	Q8TEW0	PARD3	Q96GD4	AURKB	S1178	S1178I	1178	Missense	central	0	yes	0.012	0.000	EPSD	COSMIC;GDSC;CCLE	0.010	Loss
Other_Aur_AurB_ST	P53350	PLK1	Q96GD4	AURKB	S99	R95S	95	Missense	distal	-4	no	0.014	0.013	EPSD	COSMIC	0.010	Down-regulation
Other_Aur_AurB_ST	P53350	PLK1	Q96GD4	AURKB	T366	R364Q	364	Missense	proximal	-2	no	0.064	-0.010	EPSD	COSMIC;GDSC	0.010	Loss
Other_Aur_AurB_ST	P53350	PLK1	Q96GD4	AURKB	S597	S595L	595	Missense	proximal	-2	no	0.008	0.010	EPSD	COSMIC;GDSC;CCLE	0.010	Gain
Other_Aur_AurB_ST	P18615	NELFE	Q96GD4	AURKB	S113	Q111H	111	Missense	proximal	-2	no	0.008	0.011	EPSD	COSMIC	0.010	Gain
Other_Aur_AurB_ST	P18615	NELFE	Q96GD4	AURKB	S131	S131Y	131	Missense	central	0	yes	0.078	0.000	PhosphoSitePlus	COSMIC	0.010	Loss
Other_Aur_AurB_ST	P18615	NELFE	Q96GD4	AURKB	S131	R125T	125	Missense	distal	-6	no	0.078	0.077	PhosphoSitePlus	COSMIC	0.010	Down-regulation
Other_Aur_AurB_ST	P18615	NELFE	Q96GD4	AURKB	S174	E172K	172	Missense	proximal	-2	no	0.000	0.013	EPSD	COSMIC	0.010	Gain
Other_Aur_AurB_ST	P18615	NELFE	Q96GD4	AURKB	S187	R186W	186	Missense	proximal	-1	no	0.014	0.007	EPSD	COSMIC	0.010	Loss
Other_Aur_AurB_ST	P18615	NELFE	Q96GD4	AURKB	S187	R184K	184	Missense	distal	-3	no	0.014	0.009	EPSD	COSMIC	0.010	Loss
Other_Aur_AurB_ST	P18615	NELFE	Q96GD4	AURKB	S187	R186H	186	Missense	proximal	-1	no	0.014	0.007	EPSD	COSMIC	0.010	Loss
Other_Aur_AurB_ST	P18615	NELFE	Q96GD4	AURKB	S187	S187G	187	Missense	central	0	yes	0.014	0.000	EPSD	COSMIC	0.010	Loss
Other_Aur_AurB_ST	P18615	NELFE	Q96GD4	AURKB	S191	R186W	186	Missense	distal	-5	no	0.013	0.012	EPSD	COSMIC	0.010	Down-regulation
Other_Aur_AurB_ST	P18615	NELFE	Q96GD4	AURKB	S191	R184K	184	Missense	distal	-7	no	0.013	0.014	EPSD	COSMIC	0.010	Up-regulation
Other_Aur_AurB_ST	P18615	NELFE	Q96GD4	AURKB	S191	R196Q	196	Missense	distal	5	no	0.013	0.015	EPSD	COSMIC	0.010	Up-regulation
Other_Aur_AurB_ST	P18615	NELFE	Q96GD4	AURKB	S191	R186H	186	Missense	distal	-5	no	0.013	0.012	EPSD	COSMIC	0.010	Down-regulation
Other_Aur_AurB_ST	P18615	NELFE	Q96GD4	AURKB	S249	R247H	247	Missense	proximal	-2	no	0.075	0.004	EPSD	COSMIC	0.010	Loss
Other_Aur_AurB_ST	P18615	NELFE	Q96GD4	AURKB	S249	R255Q	255	Missense	distal	6	no	0.075	0.074	EPSD	COSMIC	0.010	Down-regulation
Other_Aur_AurB_ST	P18615	NELFE	Q96GD4	AURKB	T363	R359W	359	Missense	distal	-4	no	0.018	0.017	EPSD	COSMIC	0.010	Down-regulation
Other_Aur_AurB_ST	Q02241	KIF23	Q96GD4	AURKB	S670	R668I	668	Missense	proximal	-2	no	0.069	-0.004	EPSD	COSMIC	0.010	Loss
Other_Aur_AurB_ST	Q02241	KIF23	Q96GD4	AURKB	S812	R813C	813	Missense	proximal	1	no	0.081	0.082	EPSD	COSMIC	0.010	Up-regulation
Other_Aur_AurB_ST	Q02241	KIF23	Q96GD4	AURKB	S812	S812L	812	Missense	central	0	yes	0.081	0.000	EPSD	COSMIC	0.010	Loss
Other_Aur_AurB_ST	Q02241	KIF23	Q96GD4	AURKB	S814	R813C	813	Missense	proximal	-1	no	0.014	0.007	EPSD	COSMIC	0.010	Loss
Other_Aur_AurB_ST	Q02241	KIF23	Q96GD4	AURKB	S814	S812L	812	Missense	proximal	-2	no	0.014	0.017	EPSD	COSMIC	0.010	Up-regulation
Other_Aur_AurB_ST	Q02241	KIF23	Q96GD4	AURKB	S911	R907Q	907	Missense	distal	-4	no	0.081	0.080	EPSD;PhosphoSitePlus	COSMIC	0.010	Down-regulation
Other_Aur_AurB_ST	Q02241	KIF23	Q96GD4	AURKB	S912	R907Q	907	Missense	distal	-5	no	0.077	0.075	EPSD	COSMIC	0.010	Down-regulation
Other_Aur_AurB_ST	Q02241	KIF23	Q96GD4	AURKB	S934	R932M	932	Missense	proximal	-2	no	0.069	-0.002	EPSD	COSMIC	0.010	Loss
Other_Aur_AurB_ST	Q02241	KIF23	Q96GD4	AURKB	S934	R932T	932	Missense	proximal	-2	no	0.069	0.002	EPSD	COSMIC	0.010	Loss
Other_Aur_AurB_ST	O95235	KIF20A	Q96GD4	AURKB	S244	R243K	243	Missense	proximal	-1	no	0.020	0.014	EPSD	COSMIC	0.010	Down-regulation
Other_Aur_AurB_ST	O95235	KIF20A	Q96GD4	AURKB	S402	S402R	402	Missense	central	0	yes	0.010	0.000	EPSD	COSMIC;GDSC;CCLE	0.010	Loss
Other_Aur_AurB_ST	O95235	KIF20A	Q96GD4	AURKB	S402	E403K	403	Missense	proximal	1	no	0.010	0.009	EPSD	COSMIC	0.010	Loss
Other_Aur_AurB_ST	O95235	KIF20A	Q96GD4	AURKB	S405	E403K	403	Missense	proximal	-2	no	-0.002	0.011	EPSD	COSMIC	0.010	Gain
Other_Aur_AurB_ST	O95235	KIF20A	Q96GD4	AURKB	S478	R477H	477	Missense	proximal	-1	no	0.011	0.004	EPSD	COSMIC	0.010	Loss
Other_Aur_AurB_ST	O95235	KIF20A	Q96GD4	AURKB	S677	R676Q	676	Missense	proximal	-1	no	0.078	0.071	EPSD	COSMIC	0.010	Down-regulation
Other_Aur_AurB_ST	O95235	KIF20A	Q96GD4	AURKB	T859	R856C	856	Missense	distal	-3	no	0.012	0.005	EPSD	COSMIC	0.010	Loss
Other_Aur_AurB_ST	O95235	KIF20A	Q96GD4	AURKB	T859	T859I	859	Missense	central	0	yes	0.012	0.000	EPSD	COSMIC	0.010	Loss
Other_Aur_AurB_ST	O95235	KIF20A	Q96GD4	AURKB	T859	R856Q	856	Missense	distal	-3	no	0.012	0.005	EPSD	COSMIC	0.010	Loss
Other_Aur_AurB_ST	O95235	KIF20A	Q96GD4	AURKB	S878	R874C	874	Missense	distal	-4	no	0.080	0.079	PhosphoSitePlus	COSMIC;GDSC;CCLE	0.010	Down-regulation
Other_Aur_AurB_ST	Q9Y2I6	NINL	Q96GD4	AURKB	S585	S589N	589	Missense	distal	4	no	0.068	0.067	PhosphoSitePlus;EPSD	COSMIC	0.010	Down-regulation
Other_Aur_AurB_ST	Q9Y2I6	NINL	Q96GD4	AURKB	S585	N582I	582	Missense	distal	-3	no	0.068	0.067	PhosphoSitePlus;EPSD	COSMIC	0.010	Down-regulation
Other_Aur_AurB_ST	Q9Y2I6	NINL	Q96GD4	AURKB	S585	P590S	590	Missense	distal	5	no	0.068	0.067	PhosphoSitePlus;EPSD	COSMIC	0.010	Down-regulation
Other_Aur_AurB_ST	Q9Y2I6	NINL	Q96GD4	AURKB	S821	G819R	819	Missense	proximal	-2	no	0.002	0.074	EPSD	COSMIC;GDSC;CCLE	0.010	Gain
Other_Aur_AurB_ST	Q9Y2I6	NINL	Q96GD4	AURKB	S1021	H1025R	1025	Missense	distal	4	no	0.075	0.076	EPSD	COSMIC	0.010	Up-regulation
Other_Aur_AurB_ST	Q8WWK9	CKAP2	Q96GD4	AURKB	T39	T39M	39	Missense	central	0	yes	0.079	0.000	EPSD;PhosphoSitePlus	COSMIC	0.010	Loss
Other_Aur_AurB_ST	Q8WWK9	CKAP2	Q96GD4	AURKB	S276	T280K	280	Missense	distal	4	no	0.072	0.073	EPSD	COSMIC	0.010	Up-regulation
Other_Aur_AurB_ST	Q8WWK9	CKAP2	Q96GD4	AURKB	S303	S303Y	303	Missense	central	0	yes	0.011	0.000	EPSD	COSMIC	0.010	Loss
Other_Aur_AurB_ST	Q8WWK9	CKAP2	Q96GD4	AURKB	S587	S587F	587	Missense	central	0	yes	0.073	0.000	EPSD	COSMIC	0.010	Loss
Other_Aur_AurB_ST	Q8WWK9	CKAP2	Q96GD4	AURKB	S628	R626Q	626	Missense	proximal	-2	no	0.079	0.005	PhosphoSitePlus;EPSD	COSMIC	0.010	Loss
Other_Aur_AurB_ST	Q8WWK9	CKAP2	Q96GD4	AURKB	S628	R626H	626	Missense	proximal	-2	no	0.079	0.008	PhosphoSitePlus;EPSD	COSMIC	0.010	Loss
Other_Aur_AurB_ST	Q8WWK9	CKAP2	Q96GD4	AURKB	S628	R627H	627	Missense	proximal	-1	no	0.079	0.071	PhosphoSitePlus;EPSD	COSMIC	0.010	Down-regulation
Other_Aur_AurB_ST	Q8WWK9	CKAP2	Q96GD4	AURKB	S628	E633K	633	Missense	distal	5	no	0.079	0.078	PhosphoSitePlus;EPSD	COSMIC;GDSC;CCLE	0.010	Down-regulation
Other_Aur_AurB_ST	Q9H6F5	CCDC86	Q96GD4	AURKB	S128	P125S	125	Missense	distal	-3	no	0.012	0.013	EPSD	COSMIC	0.010	Up-regulation
Other_Aur_AurB_ST	P06748	NPM1	Q96GD4	AURKB	S195	S195F	195	Missense	central	0	yes	0.011	0.000	EPSD	COSMIC	0.010	Loss
Other_Aur_AurB_ST	P06748	NPM1	Q96GD4	AURKB	T279	R277Q	277	Missense	proximal	-2	no	0.068	-0.005	EPSD	COSMIC	0.010	Loss
Other_Aur_AurB_ST	P06748	NPM1	Q96GD4	AURKB	T279	R277W	277	Missense	proximal	-2	no	0.068	-0.001	EPSD	COSMIC;GDSC;CCLE	0.010	Loss
Other_Aur_AurB_ST	P06748	NPM1	Q96GD4	AURKB	S293	W290G	290	Missense	distal	-3	no	0.074	0.073	EPSD	COSMIC	0.010	Down-regulation
Other_Aur_AurB_ST	P06748	NPM1	Q96GD4	AURKB	S293	K292E	292	Missense	proximal	-1	no	0.074	0.072	EPSD	COSMIC	0.010	Down-regulation
Other_Aur_AurB_ST	P06748	NPM1	Q96GD4	AURKB	S293	W290L	290	Missense	distal	-3	no	0.074	0.073	EPSD	COSMIC	0.010	Down-regulation
Other_Aur_AurB_ST	P06748	NPM1	Q96GD4	AURKB	S293	S293F	293	Missense	central	0	yes	0.074	0.000	EPSD	COSMIC	0.010	Loss
Other_Aur_AurB_ST	P06748	NPM1	Q96GD4	AURKB	S293	S293P	293	Missense	central	0	yes	0.074	0.000	EPSD	COSMIC	0.010	Loss
Other_Aur_AurB_ST	Q13315	ATM	Q96GD4	AURKB	S47	H42R	42	Missense	distal	-5	no	0.074	0.076	EPSD	COSMIC	0.010	Up-regulation
Other_Aur_AurB_ST	Q13315	ATM	Q96GD4	AURKB	S225	E223K	223	Missense	proximal	-2	no	0.000	0.013	EPSD	COSMIC	0.010	Gain
Other_Aur_AurB_ST	Q13315	ATM	Q96GD4	AURKB	S226	E223K	223	Missense	distal	-3	no	0.014	0.015	EPSD	COSMIC	0.010	Up-regulation
Other_Aur_AurB_ST	Q13315	ATM	Q96GD4	AURKB	S226	K224E	224	Missense	proximal	-2	no	0.014	0.001	EPSD	COSMIC	0.010	Loss
Other_Aur_AurB_ST	Q13315	ATM	Q96GD4	AURKB	T237	L236R	236	Missense	proximal	-1	no	0.005	0.013	EPSD	COSMIC	0.010	Gain
Other_Aur_AurB_ST	Q13315	ATM	Q96GD4	AURKB	S310	W308R	308	Missense	proximal	-2	no	0.010	0.079	EPSD	COSMIC	0.010	Up-regulation
Other_Aur_AurB_ST	Q13315	ATM	Q96GD4	AURKB	S333	K331N	331	Missense	proximal	-2	no	0.014	0.002	EPSD	COSMIC	0.010	Loss
Other_Aur_AurB_ST	Q13315	ATM	Q96GD4	AURKB	S333	R337S	337	Missense	distal	4	no	0.014	0.013	EPSD	COSMIC	0.010	Down-regulation
Other_Aur_AurB_ST	Q13315	ATM	Q96GD4	AURKB	S333	R337P	337	Missense	distal	4	no	0.014	0.013	EPSD	COSMIC	0.010	Down-regulation
Other_Aur_AurB_ST	Q13315	ATM	Q96GD4	AURKB	S535	P534A	534	Missense	proximal	-1	no	0.070	0.071	EPSD	COSMIC;GDSC;CCLE	0.010	Up-regulation
Other_Aur_AurB_ST	Q13315	ATM	Q96GD4	AURKB	S794	K793R	793	Missense	proximal	-1	no	0.014	0.020	EPSD	COSMIC	0.010	Up-regulation
Other_Aur_AurB_ST	Q13315	ATM	Q96GD4	AURKB	S794	K792N	792	Missense	proximal	-2	no	0.014	0.002	EPSD	COSMIC	0.010	Loss
Other_Aur_AurB_ST	Q13315	ATM	Q96GD4	AURKB	S1135	E1133K	1133	Missense	proximal	-2	no	0.009	0.022	EPSD	COSMIC;GDSC;CCLE	0.010	Gain
Other_Aur_AurB_ST	Q13315	ATM	Q96GD4	AURKB	S1770	R1768T	1768	Missense	proximal	-2	no	0.070	0.003	EPSD	COSMIC	0.010	Loss
Other_Aur_AurB_ST	Q13315	ATM	Q96GD4	AURKB	S1770	S1770L	1770	Missense	central	0	yes	0.070	0.000	EPSD	COSMIC	0.010	Loss
Other_Aur_AurB_ST	Q13315	ATM	Q96GD4	AURKB	S1883	T1880R	1880	Missense	distal	-3	no	0.007	0.013	EPSD	COSMIC	0.010	Gain
Other_Aur_AurB_ST	Q13315	ATM	Q96GD4	AURKB	T1884	T1880R	1880	Missense	distal	-4	no	0.067	0.068	EPSD	COSMIC	0.010	Up-regulation
Other_Aur_AurB_ST	Q13315	ATM	Q96GD4	AURKB	S1974	R1973T	1973	Missense	proximal	-1	no	0.018	0.011	EPSD	COSMIC	0.010	Down-regulation
Other_Aur_AurB_ST	Q13315	ATM	Q96GD4	AURKB	S1974	G1980R	1980	Missense	distal	6	no	0.018	0.019	EPSD	COSMIC	0.010	Up-regulation
Other_Aur_AurB_ST	Q13315	ATM	Q96GD4	AURKB	T1997	E1995K	1995	Missense	proximal	-2	no	-0.002	0.011	EPSD	COSMIC	0.010	Gain
Other_Aur_AurB_ST	Q13315	ATM	Q96GD4	AURKB	S2162	R2161H	2161	Missense	proximal	-1	no	0.022	0.015	EPSD	COSMIC;CCLE	0.010	Down-regulation
Other_Aur_AurB_ST	Q13315	ATM	Q96GD4	AURKB	S2310	L2307R	2307	Missense	distal	-3	no	0.004	0.011	EPSD	COSMIC	0.010	Gain
Other_Aur_AurB_ST	Q13315	ATM	Q96GD4	AURKB	S2408	E2411K	2411	Missense	distal	3	no	0.013	0.012	EPSD	COSMIC	0.010	Down-regulation
Other_Aur_AurB_ST	Q13315	ATM	Q96GD4	AURKB	T2751	T2751I	2751	Missense	central	0	yes	0.018	0.000	EPSD	COSMIC	0.010	Loss
Other_Aur_AurB_ST	Q13315	ATM	Q96GD4	AURKB	T2751	K2749I	2749	Missense	proximal	-2	no	0.018	0.004	EPSD	COSMIC;GDSC;CCLE	0.010	Loss
Other_Aur_AurB_ST	Q13315	ATM	Q96GD4	AURKB	S2812	K2811N	2811	Missense	proximal	-1	no	0.010	0.009	EPSD	COSMIC	0.010	Loss
Other_Aur_AurB_ST	Q13315	ATM	Q96GD4	AURKB	S2812	K2810Q	2810	Missense	proximal	-2	no	0.010	-0.005	EPSD	COSMIC	0.010	Loss
Other_Aur_AurB_ST	Q13315	ATM	Q96GD4	AURKB	S2812	K2811R	2811	Missense	proximal	-1	no	0.010	0.016	EPSD	COSMIC	0.010	Up-regulation
Other_Aur_AurB_ST	P46778	RPL21	Q96GD4	AURKB	S104	R108S	108	Missense	distal	4	no	0.072	0.071	PhosphoSitePlus	COSMIC	0.010	Down-regulation
Other_Aur_AurB_ST	P46778	RPL21	Q96GD4	AURKB	T124	K122T	122	Missense	proximal	-2	no	0.011	0.003	EPSD	COSMIC	0.010	Loss
Other_Aur_AurB_ST	P08670	VIM	Q96GD4	AURKB	S5	R4K	4	Missense	proximal	-1	no	0.010	0.004	EPSD	COSMIC	0.010	Loss
Other_Aur_AurB_ST	P08670	VIM	Q96GD4	AURKB	S25	S27R	27	Missense	proximal	2	no	0.066	0.067	EPSD	COSMIC	0.010	Up-regulation
Other_Aur_AurB_ST	P08670	VIM	Q96GD4	AURKB	S29	S27R	27	Missense	proximal	-2	no	0.007	0.080	EPSD	COSMIC	0.010	Gain
Other_Aur_AurB_ST	P08670	VIM	Q96GD4	AURKB	S39	R36H	36	Missense	distal	-3	no	0.013	0.006	EPSD	COSMIC	0.010	Loss
Other_Aur_AurB_ST	P08670	VIM	Q96GD4	AURKB	S39	S34P	34	Missense	distal	-5	no	0.013	0.012	EPSD	COSMIC	0.010	Down-regulation
Other_Aur_AurB_ST	P08670	VIM	Q96GD4	AURKB	S65	R64H	64	Missense	proximal	-1	no	0.013	0.006	EPSD	COSMIC	0.010	Loss
Other_Aur_AurB_ST	P08670	VIM	Q96GD4	AURKB	S65	S65F	65	Missense	central	0	yes	0.013	0.000	EPSD	COSMIC	0.010	Loss
Other_Aur_AurB_ST	P08670	VIM	Q96GD4	AURKB	S65	R69C	69	Missense	distal	4	no	0.013	0.012	EPSD	COSMIC	0.010	Down-regulation
Other_Aur_AurB_ST	P08670	VIM	Q96GD4	AURKB	S66	R64H	64	Missense	proximal	-2	no	0.068	-0.003	EPSD	COSMIC	0.010	Loss
Other_Aur_AurB_ST	P08670	VIM	Q96GD4	AURKB	S66	R71Q	71	Missense	distal	5	no	0.068	0.070	EPSD	COSMIC	0.010	Up-regulation
Other_Aur_AurB_ST	P08670	VIM	Q96GD4	AURKB	S66	S65F	65	Missense	proximal	-1	no	0.068	0.067	EPSD	COSMIC	0.010	Down-regulation
Other_Aur_AurB_ST	P08670	VIM	Q96GD4	AURKB	S72	R71Q	71	Missense	proximal	-1	no	0.015	0.007	EPSD	COSMIC	0.010	Loss
Other_Aur_AurB_ST	P08670	VIM	Q96GD4	AURKB	S72	R69C	69	Missense	distal	-3	no	0.015	0.008	EPSD	COSMIC	0.010	Loss
Other_Aur_AurB_ST	P08670	VIM	Q96GD4	AURKB	S73	R71Q	71	Missense	proximal	-2	no	0.068	-0.006	PhosphoSitePlus	COSMIC	0.010	Loss
Other_Aur_AurB_ST	P08670	VIM	Q96GD4	AURKB	S73	R69C	69	Missense	distal	-4	no	0.068	0.067	PhosphoSitePlus	COSMIC	0.010	Down-regulation
Other_Aur_AurB_ST	P08670	VIM	Q96GD4	AURKB	T361	Q359K	359	Missense	proximal	-2	no	-0.004	0.011	EPSD	COSMIC	0.010	Gain
Other_Aur_AurB_ST	P08670	VIM	Q96GD4	AURKB	T426	E425K	425	Missense	proximal	-1	no	0.070	0.071	EPSD	COSMIC	0.010	Up-regulation
Other_Aur_AurB_ST	P08670	VIM	Q96GD4	AURKB	T441	T446R	446	Missense	distal	5	no	0.016	0.014	EPSD	COSMIC	0.010	Down-regulation
Other_Aur_AurB_ST	Q8NG31	KNL1	Q96GD4	AURKB	S24	R22W	22	Missense	proximal	-2	no	0.079	0.010	PhosphoSitePlus;EPSD	COSMIC;GDSC	0.010	Down-regulation
Other_Aur_AurB_ST	Q8NG31	KNL1	Q96GD4	AURKB	S25	R22W	22	Missense	distal	-3	no	0.011	0.004	EPSD	COSMIC;GDSC	0.010	Loss
Other_Aur_AurB_ST	Q8NG31	KNL1	Q96GD4	AURKB	S56	R51K	51	Missense	distal	-5	no	0.016	0.015	EPSD	COSMIC	0.010	Down-regulation
Other_Aur_AurB_ST	Q8NG31	KNL1	Q96GD4	AURKB	S60	R57C	57	Missense	distal	-3	no	0.077	0.071	EPSD;PhosphoSitePlus	COSMIC	0.010	Down-regulation
Other_Aur_AurB_ST	Q8NG31	KNL1	Q96GD4	AURKB	S60	S60N	60	Missense	central	0	yes	0.077	0.000	EPSD;PhosphoSitePlus	COSMIC	0.010	Loss
Other_Aur_AurB_ST	Q8NG31	KNL1	Q96GD4	AURKB	S80	V77A	77	Missense	distal	-3	no	0.072	0.073	EPSD	COSMIC	0.010	Up-regulation
Other_Aur_AurB_ST	Q8NG31	KNL1	Q96GD4	AURKB	S104	R102Q	102	Missense	proximal	-2	no	0.071	-0.003	EPSD	COSMIC	0.010	Loss
Other_Aur_AurB_ST	Q8NG31	KNL1	Q96GD4	AURKB	S200	E198K	198	Missense	proximal	-2	no	0.000	0.014	EPSD	COSMIC	0.010	Gain
Other_Aur_AurB_ST	Q8NG31	KNL1	Q96GD4	AURKB	T201	E198K	198	Missense	distal	-3	no	0.010	0.011	EPSD	COSMIC	0.010	Up-regulation
Other_Aur_AurB_ST	Q8NG31	KNL1	Q96GD4	AURKB	T201	T201P	201	Missense	central	0	yes	0.010	0.000	EPSD	COSMIC	0.010	Loss
Other_Aur_AurB_ST	Q8NG31	KNL1	Q96GD4	AURKB	S634	S634F	634	Missense	central	0	yes	0.014	0.000	EPSD	COSMIC	0.010	Loss
Other_Aur_AurB_ST	Q8NG31	KNL1	Q96GD4	AURKB	S682	S682Y	682	Missense	central	0	yes	0.014	0.000	EPSD	COSMIC	0.010	Loss
Other_Aur_AurB_ST	Q8NG31	KNL1	Q96GD4	AURKB	S682	P683S	683	Missense	proximal	1	no	0.014	0.013	EPSD	COSMIC	0.010	Down-regulation
Other_Aur_AurB_ST	Q8NG31	KNL1	Q96GD4	AURKB	T811	G809R	809	Missense	proximal	-2	no	-0.002	0.070	EPSD	COSMIC	0.010	Gain
Other_Aur_AurB_ST	Q8NG31	KNL1	Q96GD4	AURKB	S1008	S1008N	1008	Missense	central	0	yes	0.070	0.000	EPSD	COSMIC;GDSC	0.010	Loss
Other_Aur_AurB_ST	Q8NG31	KNL1	Q96GD4	AURKB	T1266	N1264K	1264	Missense	proximal	-2	no	0.007	0.019	EPSD	COSMIC	0.010	Gain
Other_Aur_AurB_ST	Q8NG31	KNL1	Q96GD4	AURKB	T1267	R1265I	1265	Missense	proximal	-2	no	0.069	-0.004	EPSD	COSMIC;GDSC	0.010	Loss
Other_Aur_AurB_ST	Q8NG31	KNL1	Q96GD4	AURKB	T1267	N1264K	1264	Missense	distal	-3	no	0.069	0.070	EPSD	COSMIC	0.010	Up-regulation
Other_Aur_AurB_ST	Q8NG31	KNL1	Q96GD4	AURKB	S1652	K1651R	1651	Missense	proximal	-1	no	0.012	0.018	EPSD	COSMIC	0.010	Up-regulation
Other_Aur_AurB_ST	Q8NG31	KNL1	Q96GD4	AURKB	S1652	R1645I	1645	Missense	distal	-7	no	0.012	0.013	EPSD	COSMIC	0.010	Up-regulation
Other_Aur_AurB_ST	Q8NG31	KNL1	Q96GD4	AURKB	S1675	S1675Y	1675	Missense	central	0	yes	0.079	0.000	EPSD	COSMIC	0.010	Loss
Other_Aur_AurB_ST	Q8NG31	KNL1	Q96GD4	AURKB	S1675	R1672G	1672	Missense	distal	-3	no	0.079	0.072	EPSD	COSMIC	0.010	Down-regulation
Other_Aur_AurB_ST	Q8NG31	KNL1	Q96GD4	AURKB	S1720	S1717R	1717	Missense	distal	-3	no	0.012	0.019	EPSD	COSMIC	0.010	Up-regulation
Other_Aur_AurB_ST	Q8NG31	KNL1	Q96GD4	AURKB	S1732	N1730K	1730	Missense	proximal	-2	no	0.001	0.012	EPSD	COSMIC	0.010	Gain
Other_Aur_AurB_ST	Q8NG31	KNL1	Q96GD4	AURKB	T1824	H1822R	1822	Missense	proximal	-2	no	-0.003	0.068	EPSD	COSMIC	0.010	Gain
Other_Aur_AurB_ST	Q8NG31	KNL1	Q96GD4	AURKB	S1845	P1844Q	1844	Missense	proximal	-1	no	0.009	0.010	EPSD	COSMIC	0.010	Gain
Other_Aur_AurB_ST	Q8NG31	KNL1	Q96GD4	AURKB	S1845	P1844S	1844	Missense	proximal	-1	no	0.009	0.010	EPSD	COSMIC	0.010	Gain
Other_Aur_AurB_ST	Q8NG31	KNL1	Q96GD4	AURKB	S1869	R1867H	1867	Missense	proximal	-2	no	0.068	-0.002	EPSD	COSMIC	0.010	Loss
Other_Aur_AurB_ST	Q8NG31	KNL1	Q96GD4	AURKB	T1879	D1878Y	1878	Missense	proximal	-1	no	0.066	0.067	EPSD	COSMIC	0.010	Up-regulation
Other_Aur_AurB_ST	Q8NG31	KNL1	Q96GD4	AURKB	S1915	N1920S	1920	Missense	distal	5	no	0.070	0.069	EPSD	COSMIC	0.010	Down-regulation
Other_Aur_AurB_ST	Q69YH5	CDCA2	Q96GD4	AURKB	S76	R74L	74	Missense	proximal	-2	no	0.071	0.001	EPSD	COSMIC	0.010	Loss
Other_Aur_AurB_ST	Q69YH5	CDCA2	Q96GD4	AURKB	S76	R74Q	74	Missense	proximal	-2	no	0.071	-0.002	EPSD	COSMIC	0.010	Loss
Other_Aur_AurB_ST	Q69YH5	CDCA2	Q96GD4	AURKB	S76	R74G	74	Missense	proximal	-2	no	0.071	0.000	EPSD	COSMIC	0.010	Loss
Other_Aur_AurB_ST	Q69YH5	CDCA2	Q96GD4	AURKB	S91	R96Q	96	Missense	distal	5	no	0.085	0.087	EPSD	COSMIC	0.010	Up-regulation
Other_Aur_AurB_ST	Q69YH5	CDCA2	Q96GD4	AURKB	S91	G94R	94	Missense	distal	3	no	0.085	0.084	EPSD	COSMIC	0.010	Down-regulation
Other_Aur_AurB_ST	Q69YH5	CDCA2	Q96GD4	AURKB	S98	R96Q	96	Missense	proximal	-2	no	0.067	-0.007	EPSD	COSMIC	0.010	Loss
Other_Aur_AurB_ST	Q69YH5	CDCA2	Q96GD4	AURKB	S98	G94R	94	Missense	distal	-4	no	0.067	0.068	EPSD	COSMIC	0.010	Up-regulation
Other_Aur_AurB_ST	Q69YH5	CDCA2	Q96GD4	AURKB	S146	F152L	152	Missense	distal	6	no	0.070	0.069	EPSD	COSMIC	0.010	Down-regulation
Other_Aur_AurB_ST	Q69YH5	CDCA2	Q96GD4	AURKB	S146	H153Y	153	Missense	distal	7	no	0.070	0.069	EPSD	COSMIC	0.010	Down-regulation
Other_Aur_AurB_ST	Q69YH5	CDCA2	Q96GD4	AURKB	S146	E143K	143	Missense	distal	-3	no	0.070	0.071	EPSD	COSMIC	0.010	Up-regulation
Other_Aur_AurB_ST	Q69YH5	CDCA2	Q96GD4	AURKB	S205	R201H	201	Missense	distal	-4	no	0.077	0.076	EPSD	COSMIC	0.010	Down-regulation
Other_Aur_AurB_ST	Q69YH5	CDCA2	Q96GD4	AURKB	S247	E245K	245	Missense	proximal	-2	no	-0.002	0.012	EPSD	COSMIC	0.010	Gain
Other_Aur_AurB_ST	Q69YH5	CDCA2	Q96GD4	AURKB	T296	T294R	294	Missense	proximal	-2	no	-0.001	0.066	EPSD	COSMIC	0.010	Gain
Other_Aur_AurB_ST	Q69YH5	CDCA2	Q96GD4	AURKB	S496	N490K	490	Missense	distal	-6	no	0.011	0.012	EPSD	COSMIC	0.010	Up-regulation
Other_Aur_AurB_ST	Q69YH5	CDCA2	Q96GD4	AURKB	S507	S507P	507	Missense	central	0	yes	0.073	0.000	EPSD	COSMIC	0.010	Loss
Other_Aur_AurB_ST	Q69YH5	CDCA2	Q96GD4	AURKB	S556	K555N	555	Missense	proximal	-1	no	0.015	0.014	EPSD	COSMIC	0.010	Down-regulation
Other_Aur_AurB_ST	Q69YH5	CDCA2	Q96GD4	AURKB	S999	S999P	999	Missense	central	0	yes	0.087	0.000	EPSD	COSMIC	0.010	Loss
Other_Aur_AurB_ST	Q69YH5	CDCA2	Q96GD4	AURKB	S1000	S999P	999	Missense	proximal	-1	no	0.077	0.076	EPSD	COSMIC	0.010	Down-regulation
Other_Aur_AurB_ST	Q96CF2	CHMP4C	Q96GD4	AURKB	S210	R209P	209	Missense	proximal	-1	no	0.080	0.071	EPSD;PhosphoSitePlus	COSMIC;CCLE	0.010	Down-regulation
Other_Aur_AurB_ST	Q96CF2	CHMP4C	Q96GD4	AURKB	S210	R209L	209	Missense	proximal	-1	no	0.080	0.072	EPSD;PhosphoSitePlus	COSMIC	0.010	Down-regulation
Other_Aur_AurB_ST	Q96CF2	CHMP4C	Q96GD4	AURKB	S214	R209P	209	Missense	distal	-5	no	0.013	0.011	EPSD;PhosphoSitePlus	COSMIC;CCLE	0.010	Down-regulation
Other_Aur_AurB_ST	Q96CF2	CHMP4C	Q96GD4	AURKB	S214	R211L	211	Missense	distal	-3	no	0.013	0.007	EPSD;PhosphoSitePlus	COSMIC	0.010	Loss
Other_Aur_AurB_ST	Q96CF2	CHMP4C	Q96GD4	AURKB	S214	R209L	209	Missense	distal	-5	no	0.013	0.011	EPSD;PhosphoSitePlus	COSMIC	0.010	Down-regulation
Other_Aur_AurB_ST	P46783	RPS10	Q96GD4	AURKB	T118	R113Q	113	Missense	distal	-5	no	0.069	0.067	PhosphoSitePlus	COSMIC	0.010	Down-regulation
Other_Aur_AurB_ST	P46783	RPS10	Q96GD4	AURKB	T126	R129W	129	Missense	distal	3	no	0.063	0.064	EPSD	COSMIC;GDSC	0.010	Up-regulation
Other_Aur_AurB_ST	P46783	RPS10	Q96GD4	AURKB	T126	R129Q	129	Missense	distal	3	no	0.063	0.064	EPSD	COSMIC	0.010	Up-regulation
Other_Aur_AurB_ST	P46783	RPS10	Q96GD4	AURKB	S130	R129W	129	Missense	proximal	-1	no	0.079	0.072	EPSD	COSMIC;GDSC	0.010	Down-regulation
Other_Aur_AurB_ST	P46783	RPS10	Q96GD4	AURKB	S130	R129Q	129	Missense	proximal	-1	no	0.079	0.072	EPSD	COSMIC	0.010	Down-regulation
Other_Aur_AurB_ST	P82970	HMGN5	Q96GD4	AURKB	S20	K17N	17	Missense	distal	-3	no	0.081	0.079	EPSD;PhosphoSitePlus	COSMIC	0.010	Down-regulation
Other_Aur_AurB_ST	P82970	HMGN5	Q96GD4	AURKB	S41	M45R	45	Missense	distal	4	no	0.009	0.010	EPSD	COSMIC	0.010	Gain
Other_Aur_AurB_ST	P82970	HMGN5	Q96GD4	AURKB	T47	M45R	45	Missense	proximal	-2	no	0.000	0.071	EPSD	COSMIC	0.010	Gain
Other_Aur_AurB_ST	P82970	HMGN5	Q96GD4	AURKB	S49	K46R	46	Missense	distal	-3	no	0.008	0.013	EPSD	COSMIC	0.010	Gain
Other_Aur_AurB_ST	Q96PK6	RBM14	Q96GD4	AURKB	S220	R218C	218	Missense	proximal	-2	no	0.083	0.012	EPSD	COSMIC	0.010	Down-regulation
Other_Aur_AurB_ST	Q96PK6	RBM14	Q96GD4	AURKB	S220	R214H	214	Missense	distal	-6	no	0.083	0.081	EPSD	COSMIC	0.010	Down-regulation
Other_Aur_AurB_ST	Q96PK6	RBM14	Q96GD4	AURKB	S582	R580C	580	Missense	proximal	-2	no	0.071	0.001	EPSD	COSMIC	0.010	Loss
Other_Aur_AurB_ST	Q96PK6	RBM14	Q96GD4	AURKB	S618	R615H	615	Missense	distal	-3	no	0.078	0.071	PhosphoSitePlus;EPSD	COSMIC	0.010	Down-regulation
Other_Aur_AurB_ST	Q96PK6	RBM14	Q96GD4	AURKB	S627	S631P	631	Missense	distal	4	no	0.073	0.072	EPSD	COSMIC	0.010	Down-regulation
Other_Aur_AurB_ST	Q96PK6	RBM14	Q96GD4	AURKB	S632	S631P	631	Missense	proximal	-1	no	0.017	0.016	EPSD	COSMIC	0.010	Down-regulation
Other_Aur_AurB_ST	Q96PK6	RBM14	Q96GD4	AURKB	S632	R637S	637	Missense	distal	5	no	0.017	0.018	EPSD	COSMIC	0.010	Up-regulation
Other_Aur_AurB_ST	Q5T5U3	ARHGAP21	Q96GD4	AURKB	T6	G11R	11	Missense	distal	5	no	0.077	0.075	EPSD	COSMIC	0.010	Down-regulation
Other_Aur_AurB_ST	Q5T5U3	ARHGAP21	Q96GD4	AURKB	T55	R54I	54	Missense	proximal	-1	no	0.015	0.008	EPSD	COSMIC	0.010	Loss
Other_Aur_AurB_ST	Q5T5U3	ARHGAP21	Q96GD4	AURKB	S56	R54I	54	Missense	proximal	-2	no	0.071	-0.001	EPSD	COSMIC	0.010	Loss
Other_Aur_AurB_ST	Q5T5U3	ARHGAP21	Q96GD4	AURKB	S440	R437K	437	Missense	distal	-3	no	0.086	0.081	EPSD	COSMIC	0.010	Down-regulation
Other_Aur_AurB_ST	Q5T5U3	ARHGAP21	Q96GD4	AURKB	S440	R438Q	438	Missense	proximal	-2	no	0.086	0.012	EPSD	COSMIC	0.010	Down-regulation
Other_Aur_AurB_ST	Q5T5U3	ARHGAP21	Q96GD4	AURKB	S440	S440F	440	Missense	central	0	yes	0.086	0.000	EPSD	COSMIC	0.010	Loss
Other_Aur_AurB_ST	Q5T5U3	ARHGAP21	Q96GD4	AURKB	T441	R437K	437	Missense	distal	-4	no	0.075	0.074	EPSD	COSMIC	0.010	Down-regulation
Other_Aur_AurB_ST	Q5T5U3	ARHGAP21	Q96GD4	AURKB	T441	R438Q	438	Missense	distal	-3	no	0.075	0.068	EPSD	COSMIC	0.010	Down-regulation
Other_Aur_AurB_ST	Q5T5U3	ARHGAP21	Q96GD4	AURKB	T441	S440F	440	Missense	proximal	-1	no	0.075	0.074	EPSD	COSMIC	0.010	Down-regulation
Other_Aur_AurB_ST	Q5T5U3	ARHGAP21	Q96GD4	AURKB	S442	R437K	437	Missense	distal	-5	no	0.010	0.008	EPSD	COSMIC	0.010	Loss
Other_Aur_AurB_ST	Q5T5U3	ARHGAP21	Q96GD4	AURKB	S442	R438Q	438	Missense	distal	-4	no	0.010	0.009	EPSD	COSMIC	0.010	Loss
Other_Aur_AurB_ST	Q5T5U3	ARHGAP21	Q96GD4	AURKB	S456	Q451R	451	Missense	distal	-5	no	0.011	0.013	EPSD	COSMIC	0.010	Up-regulation
Other_Aur_AurB_ST	Q5T5U3	ARHGAP21	Q96GD4	AURKB	S636	T633K	633	Missense	distal	-3	no	0.013	0.014	EPSD	COSMIC	0.010	Up-regulation
Other_Aur_AurB_ST	Q5T5U3	ARHGAP21	Q96GD4	AURKB	T746	R744G	744	Missense	proximal	-2	no	0.066	-0.006	EPSD	COSMIC	0.010	Loss
Other_Aur_AurB_ST	Q5T5U3	ARHGAP21	Q96GD4	AURKB	S914	S914F	914	Missense	central	0	yes	0.011	0.000	EPSD	COSMIC	0.010	Loss
Other_Aur_AurB_ST	Q5T5U3	ARHGAP21	Q96GD4	AURKB	S914	S914Y	914	Missense	central	0	yes	0.011	0.000	EPSD	COSMIC	0.010	Loss
Other_Aur_AurB_ST	Q5T5U3	ARHGAP21	Q96GD4	AURKB	S1395	S1398T	1398	Missense	distal	3	no	0.009	0.010	EPSD	COSMIC	0.010	Gain
Other_Aur_AurB_ST	P45973	CBX5	Q96GD4	AURKB	T5	G2R	2	Missense	distal	-3	no	0.009	0.016	EPSD	COSMIC	0.010	Gain
Other_Aur_AurB_ST	P45973	CBX5	Q96GD4	AURKB	T8	G2R	2	Missense	distal	-6	no	0.016	0.017	EPSD	COSMIC	0.010	Up-regulation
Other_Aur_AurB_ST	P45973	CBX5	Q96GD4	AURKB	S92	S92Y	92	Missense	central	0	yes	0.073	0.000	PhosphoSitePlus	COSMIC	0.010	Loss
Other_Aur_AurB_ST	P45973	CBX5	Q96GD4	AURKB	S92	R90K	90	Missense	proximal	-2	no	0.073	0.014	PhosphoSitePlus	COSMIC	0.010	Down-regulation
Other_Aur_AurB_ST	Q8IVT2	MISP	Q96GD4	AURKB	S67	G65R	65	Missense	proximal	-2	no	0.001	0.073	EPSD	COSMIC	0.010	Gain
Other_Aur_AurB_ST	Q8IVT2	MISP	Q96GD4	AURKB	T287	P285R	285	Missense	proximal	-2	no	-0.006	0.068	EPSD	COSMIC	0.010	Gain
Other_Aur_AurB_ST	Q8IVT2	MISP	Q96GD4	AURKB	S348	E343K	343	Missense	distal	-5	no	0.069	0.070	PhosphoSitePlus	COSMIC	0.010	Up-regulation
Other_Aur_AurB_ST	Q8IVT2	MISP	Q96GD4	AURKB	T377	A375T	375	Missense	proximal	-2	no	0.009	0.010	EPSD	COSMIC	0.010	Gain
Other_Aur_AurB_ST	Q8IVT2	MISP	Q96GD4	AURKB	T464	S466F	466	Missense	proximal	2	no	0.012	0.011	EPSD	COSMIC	0.010	Down-regulation
Other_Aur_AurB_ST	Q8IVT2	MISP	Q96GD4	AURKB	T464	T464P	464	Missense	central	0	yes	0.012	0.000	EPSD	COSMIC	0.010	Loss
Other_Aur_AurB_ST	P08238	HSP90AB1	Q96GD4	AURKB	S365	M363R	363	Missense	proximal	-2	no	0.000	0.071	EPSD	COSMIC	0.010	Gain
Other_Aur_AurB_ST	P08238	HSP90AB1	Q96GD4	AURKB	S398	Q396K	396	Missense	proximal	-2	no	-0.001	0.013	EPSD	COSMIC	0.010	Gain
Other_Aur_AurB_ST	P08238	HSP90AB1	Q96GD4	AURKB	S445	E443K	443	Missense	proximal	-2	no	0.000	0.013	EPSD	COSMIC;GDSC;CCLE	0.010	Gain
Other_Aur_AurB_ST	P08238	HSP90AB1	Q96GD4	AURKB	S452	R450H	450	Missense	proximal	-2	no	0.079	0.009	PhosphoSitePlus;EPSD	COSMIC;GDSC	0.010	Loss
Other_Aur_AurB_ST	P08238	HSP90AB1	Q96GD4	AURKB	S452	R448L	448	Missense	distal	-4	no	0.079	0.078	PhosphoSitePlus;EPSD	COSMIC	0.010	Down-regulation
Other_Aur_AurB_ST	P08238	HSP90AB1	Q96GD4	AURKB	S452	R456H	456	Missense	distal	4	no	0.079	0.078	PhosphoSitePlus;EPSD	COSMIC	0.010	Down-regulation
Other_Aur_AurB_ST	P08238	HSP90AB1	Q96GD4	AURKB	S452	R456C	456	Missense	distal	4	no	0.079	0.078	PhosphoSitePlus;EPSD	COSMIC	0.010	Down-regulation
Other_Aur_AurB_ST	Q9UPY8	MAPRE3	Q96GD4	AURKB	S162	R160K	160	Missense	proximal	-2	no	0.071	0.012	EPSD	COSMIC	0.010	Down-regulation
Other_Aur_AurB_ST	Q9UPY8	MAPRE3	Q96GD4	AURKB	S176	R174Q	174	Missense	proximal	-2	no	0.072	-0.001	PhosphoSitePlus	COSMIC	0.010	Loss
Other_Aur_AurB_ST	Q9UPY8	MAPRE3	Q96GD4	AURKB	S176	S176I	176	Missense	central	0	yes	0.072	0.000	PhosphoSitePlus	COSMIC	0.010	Loss
Other_Aur_AurB_ST	Q9UPY8	MAPRE3	Q96GD4	AURKB	S176	A179P	179	Missense	distal	3	no	0.072	0.073	PhosphoSitePlus	COSMIC;GDSC;CCLE	0.010	Up-regulation
Other_Aur_AurB_ST	Q9H211	CDT1	Q96GD4	AURKB	S463	R462Q	462	Missense	proximal	-1	no	0.011	0.003	EPSD	COSMIC;CCLE	0.010	Loss
Other_Aur_AurB_ST	Q9UJ70	NAGK	Q96GD4	AURKB	S70	L73R	73	Missense	distal	3	no	0.010	0.009	EPSD	COSMIC	0.010	Loss
Other_Aur_AurB_ST	Q9UJ70	NAGK	Q96GD4	AURKB	S74	L73R	73	Missense	proximal	-1	no	0.002	0.010	EPSD	COSMIC	0.010	Gain
Other_Aur_AurB_ST	Q8WWI1	LMO7	Q96GD4	AURKB	S221	R219C	219	Missense	proximal	-2	no	0.074	0.003	EPSD	COSMIC	0.010	Loss
Other_Aur_AurB_ST	Q8WWI1	LMO7	Q96GD4	AURKB	S221	G224S	224	Missense	distal	3	no	0.074	0.073	EPSD	COSMIC;GDSC	0.010	Down-regulation
Other_Aur_AurB_ST	Q8WWI1	LMO7	Q96GD4	AURKB	S300	R297S	297	Missense	distal	-3	no	0.079	0.072	PhosphoSitePlus;EPSD	COSMIC	0.010	Down-regulation
Other_Aur_AurB_ST	Q8WWI1	LMO7	Q96GD4	AURKB	S300	S300L	300	Missense	central	0	yes	0.079	0.000	PhosphoSitePlus;EPSD	COSMIC	0.010	Loss
Other_Aur_AurB_ST	Q8WWI1	LMO7	Q96GD4	AURKB	S300	S295L	295	Missense	distal	-5	no	0.079	0.078	PhosphoSitePlus;EPSD	COSMIC	0.010	Down-regulation
Other_Aur_AurB_ST	Q8WWI1	LMO7	Q96GD4	AURKB	S342	R341K	341	Missense	proximal	-1	no	0.078	0.072	EPSD	COSMIC	0.010	Down-regulation
Other_Aur_AurB_ST	Q8WWI1	LMO7	Q96GD4	AURKB	S342	E337K	337	Missense	distal	-5	no	0.078	0.079	EPSD	COSMIC	0.010	Up-regulation
Other_Aur_AurB_ST	Q8WWI1	LMO7	Q96GD4	AURKB	S345	R341K	341	Missense	distal	-4	no	0.011	0.010	EPSD	COSMIC	0.010	Down-regulation
Other_Aur_AurB_ST	Q8WWI1	LMO7	Q96GD4	AURKB	S345	W343G	343	Missense	proximal	-2	no	0.011	0.009	EPSD	COSMIC	0.010	Loss
Other_Aur_AurB_ST	Q8WWI1	LMO7	Q96GD4	AURKB	S392	R391W	391	Missense	proximal	-1	no	0.013	0.006	EPSD	COSMIC	0.010	Loss
Other_Aur_AurB_ST	Q8WWI1	LMO7	Q96GD4	AURKB	S540	R537K	537	Missense	distal	-3	no	0.019	0.014	EPSD	COSMIC	0.010	Down-regulation
Other_Aur_AurB_ST	Q8WWI1	LMO7	Q96GD4	AURKB	S751	S751I	751	Missense	central	0	yes	0.078	0.000	EPSD;PhosphoSitePlus	COSMIC	0.010	Loss
Other_Aur_AurB_ST	Q8WWI1	LMO7	Q96GD4	AURKB	S751	R748T	748	Missense	distal	-3	no	0.078	0.071	EPSD;PhosphoSitePlus	COSMIC	0.010	Down-regulation
Other_Aur_AurB_ST	Q8WWI1	LMO7	Q96GD4	AURKB	T909	R907S	907	Missense	proximal	-2	no	0.070	-0.003	EPSD	COSMIC	0.010	Loss
Other_Aur_AurB_ST	Q8WWI1	LMO7	Q96GD4	AURKB	S1044	P1049S	1049	Missense	distal	5	no	0.073	0.072	EPSD	COSMIC	0.010	Down-regulation
Other_Aur_AurB_ST	Q8WWI1	LMO7	Q96GD4	AURKB	S1052	G1050R	1050	Missense	proximal	-2	no	-0.001	0.071	EPSD	COSMIC	0.010	Gain
Other_Aur_AurB_ST	Q8WWI1	LMO7	Q96GD4	AURKB	S1454	E1457K	1457	Missense	distal	3	no	0.079	0.078	EPSD	COSMIC	0.010	Down-regulation
Other_Aur_AurB_ST	Q8WWI1	LMO7	Q96GD4	AURKB	T1478	R1475H	1475	Missense	distal	-3	no	0.024	0.018	EPSD	COSMIC	0.010	Down-regulation
Other_Aur_AurB_ST	Q8WWI1	LMO7	Q96GD4	AURKB	T1478	R1475C	1475	Missense	distal	-3	no	0.024	0.018	EPSD	COSMIC	0.010	Down-regulation
Other_Aur_AurB_ST	Q6NZI2	CAVIN1	Q96GD4	AURKB	S118	V119I	119	Missense	proximal	1	no	0.022	0.021	EPSD	COSMIC	0.010	Down-regulation
Other_Aur_AurB_ST	Q6NZI2	CAVIN1	Q96GD4	AURKB	S118	K116N	116	Missense	proximal	-2	no	0.022	0.010	EPSD	COSMIC	0.010	Down-regulation
Other_Aur_AurB_ST	Q6NZI2	CAVIN1	Q96GD4	AURKB	S118	R115S	115	Missense	distal	-3	no	0.022	0.015	EPSD	COSMIC;GDSC	0.010	Down-regulation
Other_Aur_AurB_ST	Q6NZI2	CAVIN1	Q96GD4	AURKB	S167	K173N	173	Missense	distal	6	no	0.011	0.010	EPSD	COSMIC	0.010	Down-regulation
Other_Aur_AurB_ST	Q6NZI2	CAVIN1	Q96GD4	AURKB	S167	A164T	164	Missense	distal	-3	no	0.011	0.010	EPSD	COSMIC	0.010	Down-regulation
Other_Aur_AurB_ST	Q6NZI2	CAVIN1	Q96GD4	AURKB	S175	K173N	173	Missense	proximal	-2	no	0.013	0.001	EPSD	COSMIC	0.010	Loss
Other_Aur_AurB_ST	Q6NZI2	CAVIN1	Q96GD4	AURKB	T269	R273H	273	Missense	distal	4	no	0.071	0.070	EPSD	COSMIC	0.010	Down-regulation
Other_Aur_AurB_ST	Q6NZI2	CAVIN1	Q96GD4	AURKB	T269	R267W	267	Missense	proximal	-2	no	0.071	0.002	EPSD	COSMIC	0.010	Loss
Other_Aur_AurB_ST	Q6NZI2	CAVIN1	Q96GD4	AURKB	T269	R267Q	267	Missense	proximal	-2	no	0.071	-0.003	EPSD	COSMIC	0.010	Loss
Other_Aur_AurB_ST	Q6NZI2	CAVIN1	Q96GD4	AURKB	S300	R294Q	294	Missense	distal	-6	no	0.071	0.070	PhosphoSitePlus	COSMIC	0.010	Down-regulation
Other_Aur_AurB_ST	Q6NZI2	CAVIN1	Q96GD4	AURKB	S300	R298H	298	Missense	proximal	-2	no	0.071	0.001	PhosphoSitePlus	COSMIC	0.010	Loss
Other_Aur_AurB_ST	Q6NZI2	CAVIN1	Q96GD4	AURKB	S300	R298C	298	Missense	proximal	-2	no	0.071	0.001	PhosphoSitePlus	COSMIC	0.010	Loss
Other_Aur_AurB_ST	Q6NZI2	CAVIN1	Q96GD4	AURKB	S300	S300C	300	Missense	central	0	yes	0.071	0.000	PhosphoSitePlus	COSMIC	0.010	Loss
Other_Aur_AurB_ST	Q6NZI2	CAVIN1	Q96GD4	AURKB	S311	R310C	310	Missense	proximal	-1	no	0.011	0.003	EPSD	COSMIC	0.010	Loss
Other_Aur_AurB_ST	Q6NZI2	CAVIN1	Q96GD4	AURKB	S311	A309V	309	Missense	proximal	-2	no	0.011	0.005	EPSD	COSMIC	0.010	Loss
Other_Aur_AurB_ST	Q6NZI2	CAVIN1	Q96GD4	AURKB	S365	R362W	362	Missense	distal	-3	no	0.076	0.070	EPSD	COSMIC	0.010	Down-regulation
Other_Aur_AurB_ST	Q6NZI2	CAVIN1	Q96GD4	AURKB	S365	R362P	362	Missense	distal	-3	no	0.076	0.069	EPSD	COSMIC	0.010	Down-regulation
Other_Aur_AurB_ST	Q6NZI2	CAVIN1	Q96GD4	AURKB	S365	S365I	365	Missense	central	0	yes	0.076	0.000	EPSD	COSMIC	0.010	Loss
Other_Aur_AurB_ST	Q8IX03	WWC1	Q96GD4	AURKB	S793	S793N	793	Missense	central	0	yes	0.012	0.000	EPSD	COSMIC	0.010	Loss
Other_Aur_AurB_ST	Q8IX03	WWC1	Q96GD4	AURKB	S876	E873K	873	Missense	distal	-3	no	0.012	0.013	EPSD	COSMIC	0.010	Up-regulation
Other_Aur_AurB_ST	Q8IX03	WWC1	Q96GD4	AURKB	S962	R966P	966	Missense	distal	4	no	0.069	0.068	EPSD	COSMIC	0.010	Down-regulation
Other_Aur_AurB_ST	Q9Y5B9	SUPT16H	Q96GD4	AURKB	S117	K120R	120	Missense	distal	3	no	0.013	0.012	EPSD	COSMIC	0.010	Down-regulation
Other_Aur_AurB_ST	Q9Y5B9	SUPT16H	Q96GD4	AURKB	S508	Q503K	503	Missense	distal	-5	no	0.073	0.074	EPSD	COSMIC	0.010	Up-regulation
Other_Aur_AurB_ST	Q9Y5B9	SUPT16H	Q96GD4	AURKB	S650	Q648R	648	Missense	proximal	-2	no	-0.002	0.072	EPSD	COSMIC	0.010	Gain
Other_Aur_AurB_ST	Q9Y5B9	SUPT16H	Q96GD4	AURKB	T690	R688H	688	Missense	proximal	-2	no	0.070	-0.001	EPSD	COSMIC	0.010	Loss
Other_Aur_AurB_ST	Q9Y5B9	SUPT16H	Q96GD4	AURKB	T894	L891P	891	Missense	distal	-3	no	0.010	0.009	EPSD	COSMIC	0.010	Loss
Other_Aur_AurB_ST	Q9Y5B9	SUPT16H	Q96GD4	AURKB	T894	E895K	895	Missense	proximal	1	no	0.010	0.009	EPSD	COSMIC	0.010	Loss
Other_Aur_AurB_ST	Q9Y5B9	SUPT16H	Q96GD4	AURKB	S1023	R1018Q	1018	Missense	distal	-5	no	0.020	0.018	EPSD	COSMIC	0.010	Down-regulation
Other_Aur_AurB_ST	Q9Y5B9	SUPT16H	Q96GD4	AURKB	S1031	R1029H	1029	Missense	proximal	-2	no	0.071	0.000	EPSD	COSMIC	0.010	Loss
Other_Aur_AurB_ST	Q92538	GBF1	Q96GD4	AURKB	T608	Q603R	603	Missense	distal	-5	no	0.012	0.014	EPSD	COSMIC	0.010	Up-regulation
Other_Aur_AurB_ST	Q92538	GBF1	Q96GD4	AURKB	S684	R682Q	682	Missense	proximal	-2	no	0.074	0.000	EPSD	COSMIC	0.010	Loss
Other_Aur_AurB_ST	Q92538	GBF1	Q96GD4	AURKB	S1453	R1448C	1448	Missense	distal	-5	no	0.017	0.015	EPSD	COSMIC	0.010	Down-regulation
Other_Aur_AurB_ST	Q92538	GBF1	Q96GD4	AURKB	S1453	S1453F	1453	Missense	central	0	yes	0.017	0.000	EPSD	COSMIC	0.010	Loss
Other_Aur_AurB_ST	O15392	BIRC5	Q96GD4	AURKB	S20	H17R	17	Missense	distal	-3	no	0.072	0.078	EPSD	COSMIC	0.010	Up-regulation
Other_Aur_AurB_ST	P62917	RPL8	Q96GD4	AURKB	T73	R72W	72	Missense	proximal	-1	no	0.019	0.012	EPSD	COSMIC	0.010	Down-regulation
Other_Aur_AurB_ST	P62917	RPL8	Q96GD4	AURKB	T73	K70E	70	Missense	distal	-3	no	0.019	0.018	EPSD	COSMIC	0.010	Down-regulation
Other_Aur_AurB_ST	P62917	RPL8	Q96GD4	AURKB	T73	R68W	68	Missense	distal	-5	no	0.019	0.017	EPSD	COSMIC;GDSC;CCLE	0.010	Down-regulation
Other_Aur_AurB_ST	Q9Y520	PRRC2C	Q96GD4	AURKB	S384	Q382K	382	Missense	proximal	-2	no	-0.003	0.012	EPSD	COSMIC	0.010	Gain
Other_Aur_AurB_ST	Q9Y520	PRRC2C	Q96GD4	AURKB	T402	T402I	402	Missense	central	0	yes	0.065	0.000	EPSD	COSMIC	0.010	Loss
Other_Aur_AurB_ST	Q9Y520	PRRC2C	Q96GD4	AURKB	S453	Q451H	451	Missense	proximal	-2	no	0.007	0.011	EPSD	COSMIC	0.010	Gain
Other_Aur_AurB_ST	Q9Y520	PRRC2C	Q96GD4	AURKB	S834	V832A	832	Missense	proximal	-2	no	0.005	0.010	EPSD	COSMIC	0.010	Gain
Other_Aur_AurB_ST	Q9Y520	PRRC2C	Q96GD4	AURKB	S924	R923I	923	Missense	proximal	-1	no	0.026	0.019	EPSD	COSMIC;CCLE	0.010	Down-regulation
Other_Aur_AurB_ST	Q9Y520	PRRC2C	Q96GD4	AURKB	S924	H927P	927	Missense	distal	3	no	0.026	0.027	EPSD	COSMIC	0.010	Up-regulation
Other_Aur_AurB_ST	Q9Y520	PRRC2C	Q96GD4	AURKB	S976	R974Q	974	Missense	proximal	-2	no	0.068	-0.006	EPSD	COSMIC	0.010	Loss
Other_Aur_AurB_ST	Q9Y520	PRRC2C	Q96GD4	AURKB	S998	R1002K	1002	Missense	distal	4	no	0.070	0.069	EPSD	COSMIC	0.010	Down-regulation
Other_Aur_AurB_ST	Q9Y520	PRRC2C	Q96GD4	AURKB	S998	R1002M	1002	Missense	distal	4	no	0.070	0.069	EPSD	COSMIC	0.010	Down-regulation
Other_Aur_AurB_ST	Q9Y520	PRRC2C	Q96GD4	AURKB	S998	P997S	997	Missense	proximal	-1	no	0.070	0.071	EPSD	COSMIC;CCLE	0.010	Up-regulation
Other_Aur_AurB_ST	Q9Y520	PRRC2C	Q96GD4	AURKB	S1100	P1099S	1099	Missense	proximal	-1	no	0.011	0.012	EPSD	COSMIC	0.010	Up-regulation
Other_Aur_AurB_ST	Q9Y520	PRRC2C	Q96GD4	AURKB	S1242	R1245W	1245	Missense	distal	3	no	0.009	0.010	EPSD	COSMIC	0.010	Gain
Other_Aur_AurB_ST	Q9Y520	PRRC2C	Q96GD4	AURKB	S1242	R1245Q	1245	Missense	distal	3	no	0.009	0.010	EPSD	COSMIC	0.010	Gain
Other_Aur_AurB_ST	Q9Y520	PRRC2C	Q96GD4	AURKB	S1246	R1245W	1245	Missense	proximal	-1	no	0.014	0.007	EPSD	COSMIC	0.010	Loss
Other_Aur_AurB_ST	Q9Y520	PRRC2C	Q96GD4	AURKB	S1246	R1245Q	1245	Missense	proximal	-1	no	0.014	0.006	EPSD	COSMIC	0.010	Loss
Other_Aur_AurB_ST	Q9Y520	PRRC2C	Q96GD4	AURKB	S1263	R1261W	1261	Missense	proximal	-2	no	0.073	0.004	EPSD	COSMIC	0.010	Loss
Other_Aur_AurB_ST	Q9Y520	PRRC2C	Q96GD4	AURKB	S1360	R1358H	1358	Missense	proximal	-2	no	0.072	0.002	EPSD	COSMIC;CCLE	0.010	Loss
Other_Aur_AurB_ST	Q9Y520	PRRC2C	Q96GD4	AURKB	S1363	R1358H	1358	Missense	distal	-5	no	0.075	0.073	EPSD	COSMIC;CCLE	0.010	Down-regulation
Other_Aur_AurB_ST	Q9Y520	PRRC2C	Q96GD4	AURKB	S1363	R1366Q	1366	Missense	distal	3	no	0.075	0.076	EPSD	COSMIC	0.010	Up-regulation
Other_Aur_AurB_ST	Q9Y520	PRRC2C	Q96GD4	AURKB	S1503	E1501K	1501	Missense	proximal	-2	no	-0.004	0.010	EPSD	COSMIC	0.010	Gain
Other_Aur_AurB_ST	Q9Y520	PRRC2C	Q96GD4	AURKB	S1576	R1571G	1571	Missense	distal	-5	no	0.077	0.076	EPSD	COSMIC;CCLE	0.010	Down-regulation
Other_Aur_AurB_ST	Q9Y520	PRRC2C	Q96GD4	AURKB	S1576	S1576N	1576	Missense	central	0	yes	0.077	0.000	EPSD	COSMIC	0.010	Loss
Other_Aur_AurB_ST	Q9Y520	PRRC2C	Q96GD4	AURKB	S1576	N1572K	1572	Missense	distal	-4	no	0.077	0.078	EPSD	COSMIC	0.010	Up-regulation
Other_Aur_AurB_ST	Q9Y520	PRRC2C	Q96GD4	AURKB	S1576	R1575K	1575	Missense	proximal	-1	no	0.077	0.071	EPSD	COSMIC	0.010	Down-regulation
Other_Aur_AurB_ST	Q9Y520	PRRC2C	Q96GD4	AURKB	S1624	S1624P	1624	Missense	central	0	yes	0.012	0.000	EPSD	COSMIC	0.010	Loss
Other_Aur_AurB_ST	Q9Y520	PRRC2C	Q96GD4	AURKB	S1624	K1622R	1622	Missense	proximal	-2	no	0.012	0.070	EPSD	COSMIC	0.010	Up-regulation
Other_Aur_AurB_ST	Q9Y520	PRRC2C	Q96GD4	AURKB	S1624	S1624C	1624	Missense	central	0	yes	0.012	0.000	EPSD	COSMIC	0.010	Loss
Other_Aur_AurB_ST	Q9Y520	PRRC2C	Q96GD4	AURKB	S2143	R2148K	2148	Missense	distal	5	no	0.010	0.012	EPSD	COSMIC	0.010	Up-regulation
Other_Aur_AurB_ST	Q9Y520	PRRC2C	Q96GD4	AURKB	T2150	R2148K	2148	Missense	proximal	-2	no	0.066	0.007	EPSD	COSMIC	0.010	Loss
Other_Aur_AurB_ST	Q9Y520	PRRC2C	Q96GD4	AURKB	S2268	R2264S	2264	Missense	distal	-4	no	0.014	0.013	EPSD	COSMIC	0.010	Down-regulation
Other_Aur_AurB_ST	Q9Y520	PRRC2C	Q96GD4	AURKB	S2268	E2265K	2265	Missense	distal	-3	no	0.014	0.015	EPSD	COSMIC	0.010	Up-regulation
Other_Aur_AurB_ST	Q9Y520	PRRC2C	Q96GD4	AURKB	S2482	Q2480R	2480	Missense	proximal	-2	no	-0.004	0.070	EPSD	COSMIC	0.010	Gain
Other_Aur_AurB_ST	Q9Y520	PRRC2C	Q96GD4	AURKB	T2681	T2681A	2681	Missense	central	0	yes	0.068	0.000	EPSD	COSMIC	0.010	Loss
Other_Aur_AurB_ST	Q9Y266	NUDC	Q96GD4	AURKB	T40	R37Q	37	Missense	distal	-3	no	0.078	0.071	PhosphoSitePlus	COSMIC	0.010	Down-regulation
Other_Aur_AurB_ST	Q9Y266	NUDC	Q96GD4	AURKB	S285	R284S	284	Missense	proximal	-1	no	0.010	0.003	EPSD	COSMIC	0.010	Loss
Other_Aur_AurB_ST	Q9BXS6	NUSAP1	Q96GD4	AURKB	T178	T178A	178	Missense	central	0	yes	0.016	0.000	EPSD	COSMIC	0.010	Loss
Other_Aur_AurB_ST	Q9BXS6	NUSAP1	Q96GD4	AURKB	S251	R249C	249	Missense	proximal	-2	no	0.074	0.004	EPSD	COSMIC	0.010	Loss
Other_Aur_AurB_ST	Q9BXS6	NUSAP1	Q96GD4	AURKB	S251	R250C	250	Missense	proximal	-1	no	0.074	0.067	EPSD	COSMIC	0.010	Down-regulation
Other_Aur_AurB_ST	Q9BXS6	NUSAP1	Q96GD4	AURKB	S305	V308M	308	Missense	distal	3	no	0.073	0.072	EPSD	COSMIC	0.010	Down-regulation
Other_Aur_AurB_ST	Q9BXS6	NUSAP1	Q96GD4	AURKB	T347	E345K	345	Missense	proximal	-2	no	-0.002	0.011	EPSD	COSMIC	0.010	Gain
Other_Aur_AurB_ST	Q9NYP9	MIS18A	Q96GD4	AURKB	S10	L7P	7	Missense	distal	-3	no	0.072	0.071	EPSD	COSMIC	0.010	Down-regulation
Other_Aur_AurB_ST	P46013	MKI67	Q96GD4	AURKB	T109	F111L	111	Missense	proximal	2	no	0.020	0.019	EPSD	COSMIC	0.010	Down-regulation
Other_Aur_AurB_ST	P46013	MKI67	Q96GD4	AURKB	S125	R123H	123	Missense	proximal	-2	no	0.075	0.004	EPSD	COSMIC	0.010	Loss
Other_Aur_AurB_ST	P46013	MKI67	Q96GD4	AURKB	S128	R123H	123	Missense	distal	-5	no	0.074	0.072	EPSD	COSMIC	0.010	Down-regulation
Other_Aur_AurB_ST	P46013	MKI67	Q96GD4	AURKB	S174	T179R	179	Missense	distal	5	no	0.014	0.012	EPSD	COSMIC	0.010	Down-regulation
Other_Aur_AurB_ST	P46013	MKI67	Q96GD4	AURKB	T284	G282R	282	Missense	proximal	-2	no	-0.005	0.067	EPSD	COSMIC	0.010	Gain
Other_Aur_AurB_ST	P46013	MKI67	Q96GD4	AURKB	S425	S425N	425	Missense	central	0	yes	0.074	0.000	EPSD	COSMIC	0.010	Loss
Other_Aur_AurB_ST	P46013	MKI67	Q96GD4	AURKB	S507	R505C	505	Missense	proximal	-2	no	0.081	0.011	EPSD	COSMIC	0.010	Down-regulation
Other_Aur_AurB_ST	P46013	MKI67	Q96GD4	AURKB	S507	R505H	505	Missense	proximal	-2	no	0.081	0.011	EPSD	COSMIC;GDSC	0.010	Down-regulation
Other_Aur_AurB_ST	P46013	MKI67	Q96GD4	AURKB	S538	R536I	536	Missense	proximal	-2	no	0.073	0.001	EPSD;PhosphoSitePlus	COSMIC	0.010	Loss
Other_Aur_AurB_ST	P46013	MKI67	Q96GD4	AURKB	S598	R596S	596	Missense	proximal	-2	no	0.086	0.013	EPSD	COSMIC	0.010	Down-regulation
Other_Aur_AurB_ST	P46013	MKI67	Q96GD4	AURKB	S598	R595H	595	Missense	distal	-3	no	0.086	0.080	EPSD	COSMIC	0.010	Down-regulation
Other_Aur_AurB_ST	P46013	MKI67	Q96GD4	AURKB	S609	S607R	607	Missense	proximal	-2	no	-0.002	0.071	EPSD	COSMIC	0.010	Gain
Other_Aur_AurB_ST	P46013	MKI67	Q96GD4	AURKB	S621	K615R	615	Missense	distal	-6	no	0.070	0.071	EPSD	COSMIC	0.010	Up-regulation
Other_Aur_AurB_ST	P46013	MKI67	Q96GD4	AURKB	S707	Q705R	705	Missense	proximal	-2	no	-0.005	0.069	EPSD	COSMIC	0.010	Gain
Other_Aur_AurB_ST	P46013	MKI67	Q96GD4	AURKB	S713	H710R	710	Missense	distal	-3	no	0.005	0.011	EPSD	COSMIC;GDSC;CCLE	0.010	Gain
Other_Aur_AurB_ST	P46013	MKI67	Q96GD4	AURKB	S825	R832W	832	Missense	distal	7	no	0.013	0.012	EPSD	COSMIC	0.010	Down-regulation
Other_Aur_AurB_ST	P46013	MKI67	Q96GD4	AURKB	S825	S825C	825	Missense	central	0	yes	0.013	0.000	EPSD	COSMIC	0.010	Loss
Other_Aur_AurB_ST	P46013	MKI67	Q96GD4	AURKB	T852	K857Q	857	Missense	distal	5	no	0.010	0.011	EPSD	COSMIC	0.010	Up-regulation
Other_Aur_AurB_ST	P46013	MKI67	Q96GD4	AURKB	T852	K857E	857	Missense	distal	5	no	0.010	0.011	EPSD	COSMIC	0.010	Up-regulation
Other_Aur_AurB_ST	P46013	MKI67	Q96GD4	AURKB	S859	K857Q	857	Missense	proximal	-2	no	0.014	-0.001	EPSD	COSMIC	0.010	Loss
Other_Aur_AurB_ST	P46013	MKI67	Q96GD4	AURKB	S859	K857E	857	Missense	proximal	-2	no	0.014	0.001	EPSD	COSMIC	0.010	Loss
Other_Aur_AurB_ST	P46013	MKI67	Q96GD4	AURKB	S875	A872V	872	Missense	distal	-3	no	0.010	0.009	EPSD	COSMIC	0.010	Loss
Other_Aur_AurB_ST	P46013	MKI67	Q96GD4	AURKB	S878	S878F	878	Missense	central	0	yes	0.011	0.000	EPSD	COSMIC	0.010	Loss
Other_Aur_AurB_ST	P46013	MKI67	Q96GD4	AURKB	S878	A872V	872	Missense	distal	-6	no	0.011	0.010	EPSD	COSMIC	0.010	Down-regulation
Other_Aur_AurB_ST	P46013	MKI67	Q96GD4	AURKB	S878	S878C	878	Missense	central	0	yes	0.011	0.000	EPSD	COSMIC	0.010	Loss
Other_Aur_AurB_ST	P46013	MKI67	Q96GD4	AURKB	T879	S878F	878	Missense	proximal	-1	no	0.069	0.068	EPSD	COSMIC	0.010	Down-regulation
Other_Aur_AurB_ST	P46013	MKI67	Q96GD4	AURKB	S1071	R1066T	1066	Missense	distal	-5	no	0.016	0.014	EPSD	COSMIC	0.010	Down-regulation
Other_Aur_AurB_ST	P46013	MKI67	Q96GD4	AURKB	T1083	R1081S	1081	Missense	proximal	-2	no	0.067	-0.006	EPSD	COSMIC	0.010	Loss
Other_Aur_AurB_ST	P46013	MKI67	Q96GD4	AURKB	S1118	E1116K	1116	Missense	proximal	-2	no	-0.003	0.010	EPSD	COSMIC	0.010	Gain
Other_Aur_AurB_ST	P46013	MKI67	Q96GD4	AURKB	T1167	G1171W	1171	Missense	distal	4	no	0.018	0.019	EPSD	COSMIC	0.010	Up-regulation
Other_Aur_AurB_ST	P46013	MKI67	Q96GD4	AURKB	T1531	R1530Q	1530	Missense	proximal	-1	no	0.026	0.019	EPSD	COSMIC	0.010	Down-regulation
Other_Aur_AurB_ST	P46013	MKI67	Q96GD4	AURKB	S1533	R1530Q	1530	Missense	distal	-3	no	0.011	0.004	EPSD	COSMIC	0.010	Loss
Other_Aur_AurB_ST	P46013	MKI67	Q96GD4	AURKB	S1736	K1734I	1734	Missense	proximal	-2	no	0.011	-0.003	EPSD	COSMIC	0.010	Loss
Other_Aur_AurB_ST	P46013	MKI67	Q96GD4	AURKB	S1736	S1736F	1736	Missense	central	0	yes	0.011	0.000	EPSD	COSMIC	0.010	Loss
Other_Aur_AurB_ST	P46013	MKI67	Q96GD4	AURKB	S1740	K1734I	1734	Missense	distal	-6	no	0.072	0.071	EPSD	COSMIC	0.010	Down-regulation
Other_Aur_AurB_ST	P46013	MKI67	Q96GD4	AURKB	S1740	A1739D	1739	Missense	proximal	-1	no	0.072	0.071	EPSD	COSMIC	0.010	Down-regulation
Other_Aur_AurB_ST	P46013	MKI67	Q96GD4	AURKB	S1751	T1749R	1749	Missense	proximal	-2	no	0.000	0.067	EPSD	COSMIC	0.010	Gain
Other_Aur_AurB_ST	P46013	MKI67	Q96GD4	AURKB	S1758	K1756E	1756	Missense	proximal	-2	no	0.017	0.004	EPSD	COSMIC	0.010	Loss
Other_Aur_AurB_ST	P46013	MKI67	Q96GD4	AURKB	T1775	A1778V	1778	Missense	distal	3	no	0.018	0.019	EPSD	COSMIC;GDSC;CCLE	0.010	Up-regulation
Other_Aur_AurB_ST	P46013	MKI67	Q96GD4	AURKB	S1880	R1876Q	1876	Missense	distal	-4	no	0.019	0.018	EPSD	COSMIC	0.010	Down-regulation
Other_Aur_AurB_ST	P46013	MKI67	Q96GD4	AURKB	S1880	P1877L	1877	Missense	distal	-3	no	0.019	0.020	EPSD	COSMIC	0.010	Up-regulation
Other_Aur_AurB_ST	P46013	MKI67	Q96GD4	AURKB	S1880	R1879T	1879	Missense	proximal	-1	no	0.019	0.012	EPSD	COSMIC	0.010	Down-regulation
Other_Aur_AurB_ST	P46013	MKI67	Q96GD4	AURKB	S1980	E1978K	1978	Missense	proximal	-2	no	0.000	0.014	EPSD	COSMIC	0.010	Gain
Other_Aur_AurB_ST	P46013	MKI67	Q96GD4	AURKB	S1995	T1993R	1993	Missense	proximal	-2	no	0.002	0.069	EPSD	COSMIC	0.010	Gain
Other_Aur_AurB_ST	P46013	MKI67	Q96GD4	AURKB	S2002	S2002F	2002	Missense	central	0	yes	0.011	0.000	EPSD	COSMIC	0.010	Loss
Other_Aur_AurB_ST	P46013	MKI67	Q96GD4	AURKB	T2026	T2021K	2021	Missense	distal	-5	no	0.010	0.011	EPSD	COSMIC;GDSC;CCLE	0.010	Up-regulation
Other_Aur_AurB_ST	P46013	MKI67	Q96GD4	AURKB	T2032	A2033T	2033	Missense	proximal	1	no	0.070	0.071	EPSD	COSMIC	0.010	Up-regulation
Other_Aur_AurB_ST	P46013	MKI67	Q96GD4	AURKB	T2032	K2037N	2037	Missense	distal	5	no	0.070	0.071	EPSD	COSMIC	0.010	Up-regulation
Other_Aur_AurB_ST	P46013	MKI67	Q96GD4	AURKB	T2211	T2211M	2211	Missense	central	0	yes	0.011	0.000	EPSD	COSMIC	0.010	Loss
Other_Aur_AurB_ST	P46013	MKI67	Q96GD4	AURKB	T2211	C2206Y	2206	Missense	distal	-5	no	0.011	0.012	EPSD	COSMIC	0.010	Up-regulation
Other_Aur_AurB_ST	P46013	MKI67	Q96GD4	AURKB	S2223	R2222K	2222	Missense	proximal	-1	no	0.011	0.005	EPSD	COSMIC	0.010	Loss
Other_Aur_AurB_ST	P46013	MKI67	Q96GD4	AURKB	T2332	P2331T	2331	Missense	proximal	-1	no	0.009	0.010	EPSD	COSMIC	0.010	Gain
Other_Aur_AurB_ST	P46013	MKI67	Q96GD4	AURKB	S2344	K2343R	2343	Missense	proximal	-1	no	0.007	0.013	EPSD	COSMIC	0.010	Gain
Other_Aur_AurB_ST	P46013	MKI67	Q96GD4	AURKB	T2460	K2458N	2458	Missense	proximal	-2	no	0.010	-0.002	EPSD	COSMIC	0.010	Loss
Other_Aur_AurB_ST	P46013	MKI67	Q96GD4	AURKB	T2502	S2499R	2499	Missense	distal	-3	no	0.006	0.013	EPSD	COSMIC	0.010	Gain
Other_Aur_AurB_ST	P46013	MKI67	Q96GD4	AURKB	T2504	S2499R	2499	Missense	distal	-5	no	0.008	0.010	EPSD	COSMIC	0.010	Gain
Other_Aur_AurB_ST	P46013	MKI67	Q96GD4	AURKB	S2505	S2499R	2499	Missense	distal	-6	no	0.071	0.072	EPSD	COSMIC	0.010	Up-regulation
Other_Aur_AurB_ST	P46013	MKI67	Q96GD4	AURKB	S2505	R2503W	2503	Missense	proximal	-2	no	0.071	0.001	EPSD	COSMIC	0.010	Loss
Other_Aur_AurB_ST	P46013	MKI67	Q96GD4	AURKB	T2623	R2621S	2621	Missense	proximal	-2	no	0.066	-0.007	EPSD	COSMIC	0.010	Loss
Other_Aur_AurB_ST	P46013	MKI67	Q96GD4	AURKB	S2769	S2769F	2769	Missense	central	0	yes	0.017	0.000	EPSD	COSMIC	0.010	Loss
Other_Aur_AurB_ST	P46013	MKI67	Q96GD4	AURKB	S2793	S2793N	2793	Missense	central	0	yes	0.072	0.000	EPSD	COSMIC	0.010	Loss
Other_Aur_AurB_ST	P46013	MKI67	Q96GD4	AURKB	S2828	S2828L	2828	Missense	central	0	yes	0.017	0.000	EPSD	COSMIC	0.010	Loss
Other_Aur_AurB_ST	P46013	MKI67	Q96GD4	AURKB	T3205	T3205K	3205	Missense	central	0	yes	0.073	0.000	EPSD	COSMIC	0.010	Loss
Other_Aur_AurB_ST	P46013	MKI67	Q96GD4	AURKB	S3207	T3205K	3205	Missense	proximal	-2	no	0.006	0.014	EPSD	COSMIC	0.010	Gain
Other_Aur_AurB_ST	P46013	MKI67	Q96GD4	AURKB	T3223	K3217E	3217	Missense	distal	-6	no	0.062	0.061	EPSD	COSMIC	0.010	Down-regulation
Other_Aur_AurB_ST	Q9NS23	RASSF1	Q96GD4	AURKB	T38	R36Q	36	Missense	proximal	-2	no	0.070	-0.004	EPSD	COSMIC	0.010	Loss
Other_Aur_AurB_ST	Q9NS23	RASSF1	Q96GD4	AURKB	T206	R205H	205	Missense	proximal	-1	no	0.084	0.076	EPSD	COSMIC;CCLE	0.010	Down-regulation
Other_Aur_AurB_ST	Q9NS23	RASSF1	Q96GD4	AURKB	T206	T200I	200	Missense	distal	-6	no	0.084	0.083	EPSD	COSMIC	0.010	Down-regulation
Other_Aur_AurB_ST	Q9NS23	RASSF1	Q96GD4	AURKB	S207	R205H	205	Missense	proximal	-2	no	0.078	0.007	EPSD	COSMIC;CCLE	0.010	Loss
Other_Aur_AurB_ST	Q9BW61	DDA1	Q96GD4	AURKB	S95	S95I	95	Missense	central	0	yes	0.010	0.000	EPSD	COSMIC	0.010	Loss
Other_Aur_AurB_ST	Q9BW61	DDA1	Q96GD4	AURKB	S95	A91V	91	Missense	distal	-4	no	0.010	0.009	EPSD	COSMIC;CCLE	0.010	Loss
Other_Aur_AurB_ST	O00566	MPHOSPH10	Q96GD4	AURKB	S261	K259R	259	Missense	proximal	-2	no	0.014	0.072	EPSD	COSMIC	0.010	Up-regulation
Other_Aur_AurB_ST	O00566	MPHOSPH10	Q96GD4	AURKB	T332	P336Q	336	Missense	distal	4	no	0.069	0.070	PhosphoSitePlus	COSMIC	0.010	Up-regulation
Other_Aur_AurB_ST	O00566	MPHOSPH10	Q96GD4	AURKB	T459	R457H	457	Missense	proximal	-2	no	0.071	0.000	EPSD	COSMIC	0.010	Loss
Other_Aur_AurB_ST	O00566	MPHOSPH10	Q96GD4	AURKB	T459	R457C	457	Missense	proximal	-2	no	0.071	0.000	EPSD	COSMIC;CCLE	0.010	Loss
Other_Aur_AurB_ST	O00566	MPHOSPH10	Q96GD4	AURKB	S468	L469F	469	Missense	proximal	1	no	0.014	0.013	EPSD	COSMIC	0.010	Down-regulation
Other_Aur_AurB_ST	O00566	MPHOSPH10	Q96GD4	AURKB	S603	K601N	601	Missense	proximal	-2	no	0.011	-0.001	EPSD	COSMIC	0.010	Loss
Other_Aur_AurB_ST	Q9NQZ2	UTP3	Q96GD4	AURKB	S56	A61V	61	Missense	distal	5	no	0.010	0.011	EPSD	COSMIC	0.010	Up-regulation
Other_Aur_AurB_ST	Q9NQZ2	UTP3	Q96GD4	AURKB	S343	K342R	342	Missense	proximal	-1	no	0.005	0.011	EPSD	COSMIC	0.010	Gain
Other_Aur_AurB_ST	Q9NQZ2	UTP3	Q96GD4	AURKB	T344	K342R	342	Missense	proximal	-2	no	0.008	0.066	EPSD	COSMIC	0.010	Gain
Other_Aur_AurB_ST	P14618	PKM	Q96GD4	AURKB	T95	A94V	94	Missense	proximal	-1	no	0.010	0.009	EPSD	COSMIC	0.010	Loss
Other_Aur_AurB_ST	P14618	PKM	Q96GD4	AURKB	S346	E344K	344	Missense	proximal	-2	no	-0.002	0.011	EPSD	COSMIC	0.010	Gain
Other_Aur_AurB_ST	O15523	DDX3Y	Q96GD4	AURKB	S592	K587N	587	Missense	distal	-5	no	0.068	0.067	PhosphoSitePlus	COSMIC	0.010	Down-regulation
Other_Aur_AurB_ST	Q9UQL6	HDAC5	Q96GD4	AURKB	T257	R255C	255	Missense	proximal	-2	no	0.068	-0.003	EPSD	COSMIC	0.010	Loss
Other_Aur_AurB_ST	Q9UQL6	HDAC5	Q96GD4	AURKB	S279	R284C	284	Missense	distal	5	no	0.077	0.079	EPSD	COSMIC	0.010	Up-regulation
Other_Aur_AurB_ST	Q9UQL6	HDAC5	Q96GD4	AURKB	S279	S279N	279	Missense	central	0	yes	0.077	0.000	EPSD	COSMIC	0.010	Loss
Other_Aur_AurB_ST	Q9UQL6	HDAC5	Q96GD4	AURKB	S279	R284S	284	Missense	distal	5	no	0.077	0.078	EPSD	COSMIC	0.010	Up-regulation
Other_Aur_AurB_ST	Q9UQL6	HDAC5	Q96GD4	AURKB	S1108	E1106K	1106	Missense	proximal	-2	no	0.007	0.020	EPSD	COSMIC	0.010	Gain
Other_Aur_AurB_ST	Q8TE77	SSH3	Q96GD4	AURKB	S602	R600H	600	Missense	proximal	-2	no	0.072	0.002	EPSD	COSMIC	0.010	Loss
Other_Aur_AurB_ST	Q8TE77	SSH3	Q96GD4	AURKB	S602	L606I	606	Missense	distal	4	no	0.072	0.073	EPSD	COSMIC	0.010	Up-regulation
Other_Aur_AurB_ST	Q8TE77	SSH3	Q96GD4	AURKB	S602	L597M	597	Missense	distal	-5	no	0.072	0.073	EPSD	COSMIC	0.010	Up-regulation
Other_Aur_AurB_ST	Q15149	PLEC	Q96GD4	AURKB	S714	R713W	713	Missense	proximal	-1	no	0.018	0.010	EPSD	COSMIC	0.010	Down-regulation
Other_Aur_AurB_ST	Q15149	PLEC	Q96GD4	AURKB	S714	R711Q	711	Missense	distal	-3	no	0.018	0.011	EPSD	COSMIC	0.010	Down-regulation
Other_Aur_AurB_ST	Q15149	PLEC	Q96GD4	AURKB	S751	K746R	746	Missense	distal	-5	no	0.015	0.017	EPSD	COSMIC	0.010	Up-regulation
Other_Aur_AurB_ST	Q15149	PLEC	Q96GD4	AURKB	S751	R750H	750	Missense	proximal	-1	no	0.015	0.008	EPSD	COSMIC	0.010	Loss
Other_Aur_AurB_ST	Q15149	PLEC	Q96GD4	AURKB	S751	R748C	748	Missense	distal	-3	no	0.015	0.009	EPSD	COSMIC	0.010	Loss
Other_Aur_AurB_ST	Q15149	PLEC	Q96GD4	AURKB	S794	A790V	790	Missense	distal	-4	no	0.011	0.010	EPSD	COSMIC	0.010	Down-regulation
Other_Aur_AurB_ST	Q15149	PLEC	Q96GD4	AURKB	S794	R800Q	800	Missense	distal	6	no	0.011	0.010	EPSD	COSMIC	0.010	Down-regulation
Other_Aur_AurB_ST	Q15149	PLEC	Q96GD4	AURKB	S887	R883H	883	Missense	distal	-4	no	0.018	0.017	EPSD	COSMIC	0.010	Down-regulation
Other_Aur_AurB_ST	Q15149	PLEC	Q96GD4	AURKB	S887	R884S	884	Missense	distal	-3	no	0.018	0.011	EPSD	COSMIC	0.010	Down-regulation
Other_Aur_AurB_ST	Q15149	PLEC	Q96GD4	AURKB	S1045	R1044S	1044	Missense	proximal	-1	no	0.010	0.003	EPSD	COSMIC	0.010	Loss
Other_Aur_AurB_ST	Q15149	PLEC	Q96GD4	AURKB	S1124	E1125K	1125	Missense	proximal	1	no	0.013	0.012	EPSD	COSMIC	0.010	Down-regulation
Other_Aur_AurB_ST	Q15149	PLEC	Q96GD4	AURKB	S1124	K1127R	1127	Missense	distal	3	no	0.013	0.012	EPSD	COSMIC	0.010	Down-regulation
Other_Aur_AurB_ST	Q15149	PLEC	Q96GD4	AURKB	S1124	S1124F	1124	Missense	central	0	yes	0.013	0.000	EPSD	COSMIC	0.010	Loss
Other_Aur_AurB_ST	Q15149	PLEC	Q96GD4	AURKB	S1194	E1192K	1192	Missense	proximal	-2	no	-0.002	0.011	EPSD	COSMIC	0.010	Gain
Other_Aur_AurB_ST	Q15149	PLEC	Q96GD4	AURKB	S1202	R1201Q	1201	Missense	proximal	-1	no	0.010	0.002	EPSD	COSMIC	0.010	Loss
Other_Aur_AurB_ST	Q15149	PLEC	Q96GD4	AURKB	S1352	R1347H	1347	Missense	distal	-5	no	0.074	0.073	EPSD	COSMIC	0.010	Down-regulation
Other_Aur_AurB_ST	Q15149	PLEC	Q96GD4	AURKB	S1352	L1346R	1346	Missense	distal	-6	no	0.074	0.076	EPSD	COSMIC	0.010	Up-regulation
Other_Aur_AurB_ST	Q15149	PLEC	Q96GD4	AURKB	S1554	Q1550R	1550	Missense	distal	-4	no	0.015	0.016	EPSD	COSMIC	0.010	Up-regulation
Other_Aur_AurB_ST	Q15149	PLEC	Q96GD4	AURKB	S1554	S1554N	1554	Missense	central	0	yes	0.015	0.000	EPSD	COSMIC	0.010	Loss
Other_Aur_AurB_ST	Q15149	PLEC	Q96GD4	AURKB	S1565	Q1564R	1564	Missense	proximal	-1	no	0.068	0.076	EPSD	COSMIC	0.010	Up-regulation
Other_Aur_AurB_ST	Q15149	PLEC	Q96GD4	AURKB	S1565	R1563Q	1563	Missense	proximal	-2	no	0.068	-0.005	EPSD	COSMIC	0.010	Loss
Other_Aur_AurB_ST	Q15149	PLEC	Q96GD4	AURKB	S1565	A1568V	1568	Missense	distal	3	no	0.068	0.069	EPSD	COSMIC;CCLE	0.010	Up-regulation
Other_Aur_AurB_ST	Q15149	PLEC	Q96GD4	AURKB	S1566	Q1564R	1564	Missense	proximal	-2	no	0.002	0.076	EPSD	COSMIC	0.010	Gain
Other_Aur_AurB_ST	Q15149	PLEC	Q96GD4	AURKB	S1721	R1719W	1719	Missense	proximal	-2	no	0.072	0.002	EPSD	COSMIC	0.010	Loss
Other_Aur_AurB_ST	Q15149	PLEC	Q96GD4	AURKB	S1721	R1719C	1719	Missense	proximal	-2	no	0.072	0.001	EPSD	COSMIC;CCLE	0.010	Loss
Other_Aur_AurB_ST	Q15149	PLEC	Q96GD4	AURKB	S1721	K1725N	1725	Missense	distal	4	no	0.072	0.071	EPSD	COSMIC	0.010	Down-regulation
Other_Aur_AurB_ST	Q15149	PLEC	Q96GD4	AURKB	S2039	R2036H	2036	Missense	distal	-3	no	0.022	0.016	EPSD	COSMIC	0.010	Down-regulation
Other_Aur_AurB_ST	Q15149	PLEC	Q96GD4	AURKB	S2090	R2087Q	2087	Missense	distal	-3	no	0.013	0.006	EPSD	COSMIC	0.010	Loss
Other_Aur_AurB_ST	Q15149	PLEC	Q96GD4	AURKB	S2090	R2087W	2087	Missense	distal	-3	no	0.013	0.006	EPSD	COSMIC	0.010	Loss
Other_Aur_AurB_ST	Q15149	PLEC	Q96GD4	AURKB	S2090	E2093K	2093	Missense	distal	3	no	0.013	0.012	EPSD	COSMIC	0.010	Down-regulation
Other_Aur_AurB_ST	Q15149	PLEC	Q96GD4	AURKB	S2090	R2097Q	2097	Missense	distal	7	no	0.013	0.012	EPSD	COSMIC	0.010	Down-regulation
Other_Aur_AurB_ST	Q15149	PLEC	Q96GD4	AURKB	S2090	R2097L	2097	Missense	distal	7	no	0.013	0.012	EPSD	COSMIC	0.010	Down-regulation
Other_Aur_AurB_ST	Q15149	PLEC	Q96GD4	AURKB	S2090	R2097H	2097	Missense	distal	7	no	0.013	0.012	EPSD	COSMIC	0.010	Down-regulation
Other_Aur_AurB_ST	Q15149	PLEC	Q96GD4	AURKB	S2421	R2419L	2419	Missense	proximal	-2	no	0.067	-0.004	EPSD	COSMIC	0.010	Loss
Other_Aur_AurB_ST	Q15149	PLEC	Q96GD4	AURKB	S2421	R2419H	2419	Missense	proximal	-2	no	0.067	-0.004	EPSD	COSMIC	0.010	Loss
Other_Aur_AurB_ST	Q15149	PLEC	Q96GD4	AURKB	S2516	E2514K	2514	Missense	proximal	-2	no	-0.004	0.010	EPSD	COSMIC	0.010	Gain
Other_Aur_AurB_ST	Q15149	PLEC	Q96GD4	AURKB	T2625	Q2623K	2623	Missense	proximal	-2	no	-0.004	0.011	EPSD	COSMIC	0.010	Gain
Other_Aur_AurB_ST	Q15149	PLEC	Q96GD4	AURKB	S2791	S2791F	2791	Missense	central	0	yes	0.020	0.000	EPSD	COSMIC	0.010	Loss
Other_Aur_AurB_ST	Q15149	PLEC	Q96GD4	AURKB	S2791	S2791C	2791	Missense	central	0	yes	0.020	0.000	EPSD	COSMIC	0.010	Loss
Other_Aur_AurB_ST	Q15149	PLEC	Q96GD4	AURKB	S2791	S2791P	2791	Missense	central	0	yes	0.020	0.000	EPSD	COSMIC	0.010	Loss
Other_Aur_AurB_ST	Q15149	PLEC	Q96GD4	AURKB	S2791	R2787Q	2787	Missense	distal	-4	no	0.020	0.019	EPSD	COSMIC;GDSC;CCLE	0.010	Down-regulation
Other_Aur_AurB_ST	Q15149	PLEC	Q96GD4	AURKB	S2791	R2788Q	2788	Missense	distal	-3	no	0.020	0.013	EPSD	COSMIC	0.010	Down-regulation
Other_Aur_AurB_ST	Q15149	PLEC	Q96GD4	AURKB	S2833	Q2830R	2830	Missense	distal	-3	no	0.007	0.014	EPSD	COSMIC	0.010	Gain
Other_Aur_AurB_ST	Q15149	PLEC	Q96GD4	AURKB	S2834	R2832H	2832	Missense	proximal	-2	no	0.068	-0.002	EPSD	COSMIC	0.010	Loss
Other_Aur_AurB_ST	Q15149	PLEC	Q96GD4	AURKB	S2834	Q2830R	2830	Missense	distal	-4	no	0.068	0.069	EPSD	COSMIC	0.010	Up-regulation
Other_Aur_AurB_ST	Q15149	PLEC	Q96GD4	AURKB	S2834	S2834N	2834	Missense	central	0	yes	0.068	0.000	EPSD	COSMIC	0.010	Loss
Other_Aur_AurB_ST	Q15149	PLEC	Q96GD4	AURKB	S2848	S2848N	2848	Missense	central	0	yes	0.013	0.000	EPSD	COSMIC	0.010	Loss
Other_Aur_AurB_ST	Q15149	PLEC	Q96GD4	AURKB	T2886	A2890V	2890	Missense	distal	4	no	0.078	0.077	PhosphoSitePlus	COSMIC	0.010	Down-regulation
Other_Aur_AurB_ST	Q15149	PLEC	Q96GD4	AURKB	T2886	R2884L	2884	Missense	proximal	-2	no	0.078	0.007	PhosphoSitePlus	COSMIC	0.010	Loss
Other_Aur_AurB_ST	Q15149	PLEC	Q96GD4	AURKB	T3046	E3043K	3043	Missense	distal	-3	no	0.012	0.013	EPSD	COSMIC;CCLE	0.010	Up-regulation
Other_Aur_AurB_ST	Q15149	PLEC	Q96GD4	AURKB	T3088	R3083H	3083	Missense	distal	-5	no	0.067	0.065	EPSD	COSMIC	0.010	Down-regulation
Other_Aur_AurB_ST	Q15149	PLEC	Q96GD4	AURKB	S3176	S3176R	3176	Missense	central	0	yes	0.011	0.000	EPSD	COSMIC	0.010	Loss
Other_Aur_AurB_ST	Q15149	PLEC	Q96GD4	AURKB	T3370	T3370M	3370	Missense	central	0	yes	0.070	0.000	EPSD	COSMIC	0.010	Loss
Other_Aur_AurB_ST	Q15149	PLEC	Q96GD4	AURKB	S3441	R3436W	3436	Missense	distal	-5	no	0.069	0.067	EPSD	COSMIC	0.010	Down-regulation
Other_Aur_AurB_ST	Q15149	PLEC	Q96GD4	AURKB	S3441	R3436Q	3436	Missense	distal	-5	no	0.069	0.067	EPSD	COSMIC	0.010	Down-regulation
Other_Aur_AurB_ST	Q15149	PLEC	Q96GD4	AURKB	S3441	R3436L	3436	Missense	distal	-5	no	0.069	0.067	EPSD	COSMIC	0.010	Down-regulation
Other_Aur_AurB_ST	Q15149	PLEC	Q96GD4	AURKB	S3441	S3441L	3441	Missense	central	0	yes	0.069	0.000	EPSD	COSMIC	0.010	Loss
Other_Aur_AurB_ST	Q15149	PLEC	Q96GD4	AURKB	S3441	R3439M	3439	Missense	proximal	-2	no	0.069	-0.002	EPSD	COSMIC	0.010	Loss
Other_Aur_AurB_ST	Q15149	PLEC	Q96GD4	AURKB	S3441	R3446H	3446	Missense	distal	5	no	0.069	0.071	EPSD	COSMIC	0.010	Up-regulation
Other_Aur_AurB_ST	Q15149	PLEC	Q96GD4	AURKB	T3502	E3500K	3500	Missense	proximal	-2	no	-0.003	0.010	EPSD	COSMIC	0.010	Gain
Other_Aur_AurB_ST	Q15149	PLEC	Q96GD4	AURKB	T3785	R3783H	3783	Missense	proximal	-2	no	0.073	0.003	EPSD	COSMIC	0.010	Loss
Other_Aur_AurB_ST	Q15149	PLEC	Q96GD4	AURKB	T3840	Q3845K	3845	Missense	distal	5	no	0.068	0.067	EPSD	COSMIC	0.010	Down-regulation
Other_Aur_AurB_ST	Q15149	PLEC	Q96GD4	AURKB	T3970	T3970A	3970	Missense	central	0	yes	0.011	0.000	EPSD	COSMIC	0.010	Loss
Other_Aur_AurB_ST	Q15149	PLEC	Q96GD4	AURKB	T4021	R4026Q	4026	Missense	distal	5	no	0.015	0.017	EPSD	COSMIC	0.010	Up-regulation
Other_Aur_AurB_ST	Q15149	PLEC	Q96GD4	AURKB	T4021	R4026L	4026	Missense	distal	5	no	0.015	0.017	EPSD	COSMIC	0.010	Up-regulation
Other_Aur_AurB_ST	Q15149	PLEC	Q96GD4	AURKB	T4267	R4265W	4265	Missense	proximal	-2	no	0.071	0.002	EPSD	COSMIC;GDSC;CCLE	0.010	Loss
Other_Aur_AurB_ST	Q15149	PLEC	Q96GD4	AURKB	T4267	R4263L	4263	Missense	distal	-4	no	0.071	0.070	EPSD	COSMIC	0.010	Down-regulation
Other_Aur_AurB_ST	Q15149	PLEC	Q96GD4	AURKB	S4268	S4271L	4271	Missense	distal	3	no	0.017	0.018	EPSD	COSMIC	0.010	Up-regulation
Other_Aur_AurB_ST	Q15149	PLEC	Q96GD4	AURKB	S4268	R4265W	4265	Missense	distal	-3	no	0.017	0.011	EPSD	COSMIC;GDSC;CCLE	0.010	Down-regulation
Other_Aur_AurB_ST	Q15149	PLEC	Q96GD4	AURKB	S4268	R4263L	4263	Missense	distal	-5	no	0.017	0.015	EPSD	COSMIC	0.010	Down-regulation
Other_Aur_AurB_ST	Q15149	PLEC	Q96GD4	AURKB	S4272	S4272L	4272	Missense	central	0	yes	0.010	0.000	EPSD	COSMIC	0.010	Loss
Other_Aur_AurB_ST	Q15149	PLEC	Q96GD4	AURKB	S4272	S4271L	4271	Missense	proximal	-1	no	0.010	0.009	EPSD	COSMIC	0.010	Loss
Other_Aur_AurB_ST	Q15149	PLEC	Q96GD4	AURKB	S4272	S4272F	4272	Missense	central	0	yes	0.010	0.000	EPSD	COSMIC	0.010	Loss
Other_Aur_AurB_ST	Q15149	PLEC	Q96GD4	AURKB	S4336	S4336F	4336	Missense	central	0	yes	0.079	0.000	EPSD	COSMIC	0.010	Loss
Other_Aur_AurB_ST	Q15149	PLEC	Q96GD4	AURKB	S4506	S4506F	4506	Missense	central	0	yes	0.014	0.000	EPSD	COSMIC	0.010	Loss
Other_Aur_AurB_ST	Q15149	PLEC	Q96GD4	AURKB	S4506	R4500H	4500	Missense	distal	-6	no	0.014	0.013	EPSD	COSMIC;GDSC;CCLE	0.010	Down-regulation
Other_Aur_AurB_ST	Q15149	PLEC	Q96GD4	AURKB	S4634	R4639H	4639	Missense	distal	5	no	0.008	0.010	EPSD	COSMIC	0.010	Gain
Other_Aur_AurB_ST	Q15149	PLEC	Q96GD4	AURKB	S4638	G4637A	4637	Missense	proximal	-1	no	0.010	0.011	EPSD	COSMIC	0.010	Up-regulation
Other_Aur_AurB_ST	Q15149	PLEC	Q96GD4	AURKB	S4642	G4641C	4641	Missense	proximal	-1	no	0.076	0.077	EPSD	COSMIC	0.010	Up-regulation
Other_Aur_AurB_ST	Q15149	PLEC	Q96GD4	AURKB	S4642	G4637A	4637	Missense	distal	-5	no	0.076	0.077	EPSD	COSMIC	0.010	Up-regulation
Other_Aur_AurB_ST	Q15149	PLEC	Q96GD4	AURKB	S4642	R4639H	4639	Missense	distal	-3	no	0.076	0.070	EPSD	COSMIC	0.010	Down-regulation
Other_Aur_AurB_ST	Q96E39	RBMXL1	Q96GD4	AURKB	S174	G179R	179	Missense	distal	5	no	0.073	0.071	EPSD	COSMIC	0.010	Down-regulation
Other_Aur_AurB_ST	Q96E39	RBMXL1	Q96GD4	AURKB	T231	R229C	229	Missense	proximal	-2	no	0.065	-0.006	EPSD	COSMIC	0.010	Loss
Other_Aur_AurB_ST	Q96E39	RBMXL1	Q96GD4	AURKB	T231	S228P	228	Missense	distal	-3	no	0.065	0.064	EPSD	COSMIC	0.010	Down-regulation
Other_Aur_AurB_ST	Q96E39	RBMXL1	Q96GD4	AURKB	S362	R360C	360	Missense	proximal	-2	no	0.070	0.000	EPSD	COSMIC;GDSC	0.010	Loss
Other_Aur_AurB_ST	Q09666	AHNAK	Q96GD4	AURKB	T46	R45S	45	Missense	proximal	-1	no	0.010	0.003	EPSD	COSMIC	0.010	Loss
Other_Aur_AurB_ST	Q09666	AHNAK	Q96GD4	AURKB	T46	A43V	43	Missense	distal	-3	no	0.010	0.009	EPSD	COSMIC	0.010	Loss
Other_Aur_AurB_ST	Q09666	AHNAK	Q96GD4	AURKB	S93	D91N	91	Missense	proximal	-2	no	0.008	0.011	EPSD	COSMIC	0.010	Gain
Other_Aur_AurB_ST	Q09666	AHNAK	Q96GD4	AURKB	T158	T158M	158	Missense	central	0	yes	0.072	0.000	PhosphoSitePlus	COSMIC	0.010	Loss
Other_Aur_AurB_ST	Q09666	AHNAK	Q96GD4	AURKB	S332	R330G	330	Missense	proximal	-2	no	0.070	-0.002	EPSD	COSMIC	0.010	Loss
Other_Aur_AurB_ST	Q09666	AHNAK	Q96GD4	AURKB	T564	G562R	562	Missense	proximal	-2	no	0.001	0.072	EPSD	COSMIC;GDSC;CCLE	0.010	Gain
Other_Aur_AurB_ST	Q09666	AHNAK	Q96GD4	AURKB	S947	S947F	947	Missense	central	0	yes	0.011	0.000	EPSD	COSMIC	0.010	Loss
Other_Aur_AurB_ST	Q09666	AHNAK	Q96GD4	AURKB	S1007	S1007N	1007	Missense	central	0	yes	0.010	0.000	EPSD	COSMIC	0.010	Loss
Other_Aur_AurB_ST	Q09666	AHNAK	Q96GD4	AURKB	S1068	M1067V	1067	Missense	proximal	-1	no	0.012	0.011	EPSD	COSMIC	0.010	Down-regulation
Other_Aur_AurB_ST	Q09666	AHNAK	Q96GD4	AURKB	S1654	K1652T	1652	Missense	proximal	-2	no	0.011	0.002	EPSD	COSMIC	0.010	Loss
Other_Aur_AurB_ST	Q09666	AHNAK	Q96GD4	AURKB	S1856	A1852V	1852	Missense	distal	-4	no	0.011	0.010	EPSD	COSMIC	0.010	Down-regulation
Other_Aur_AurB_ST	Q09666	AHNAK	Q96GD4	AURKB	S1856	K1854N	1854	Missense	proximal	-2	no	0.011	-0.001	EPSD	COSMIC	0.010	Loss
Other_Aur_AurB_ST	Q09666	AHNAK	Q96GD4	AURKB	S2118	S2118F	2118	Missense	central	0	yes	0.011	0.000	EPSD	COSMIC	0.010	Loss
Other_Aur_AurB_ST	Q09666	AHNAK	Q96GD4	AURKB	S2387	P2389S	2389	Missense	proximal	2	no	0.011	0.012	EPSD	COSMIC	0.010	Up-regulation
Other_Aur_AurB_ST	Q09666	AHNAK	Q96GD4	AURKB	S2519	P2516S	2516	Missense	distal	-3	no	0.010	0.011	EPSD	COSMIC	0.010	Up-regulation
Other_Aur_AurB_ST	Q09666	AHNAK	Q96GD4	AURKB	S2820	W2818R	2818	Missense	proximal	-2	no	0.005	0.075	EPSD	COSMIC	0.010	Gain
Other_Aur_AurB_ST	Q09666	AHNAK	Q96GD4	AURKB	S2836	P2833A	2833	Missense	distal	-3	no	0.012	0.013	EPSD	COSMIC	0.010	Up-regulation
Other_Aur_AurB_ST	Q09666	AHNAK	Q96GD4	AURKB	S2903	M2897V	2897	Missense	distal	-6	no	0.011	0.010	EPSD	COSMIC;CCLE	0.010	Down-regulation
Other_Aur_AurB_ST	Q09666	AHNAK	Q96GD4	AURKB	S2903	S2903N	2903	Missense	central	0	yes	0.011	0.000	EPSD	COSMIC	0.010	Loss
Other_Aur_AurB_ST	Q09666	AHNAK	Q96GD4	AURKB	S2903	K2901M	2901	Missense	proximal	-2	no	0.011	-0.001	EPSD	COSMIC	0.010	Loss
Other_Aur_AurB_ST	Q09666	AHNAK	Q96GD4	AURKB	S3092	P3089T	3089	Missense	distal	-3	no	0.011	0.012	EPSD	COSMIC	0.010	Up-regulation
Other_Aur_AurB_ST	Q09666	AHNAK	Q96GD4	AURKB	S3092	S3092F	3092	Missense	central	0	yes	0.011	0.000	EPSD	COSMIC	0.010	Loss
Other_Aur_AurB_ST	Q09666	AHNAK	Q96GD4	AURKB	S3294	K3292N	3292	Missense	proximal	-2	no	0.010	-0.001	EPSD	COSMIC	0.010	Loss
Other_Aur_AurB_ST	Q09666	AHNAK	Q96GD4	AURKB	S3294	S3294Y	3294	Missense	central	0	yes	0.010	0.000	EPSD	COSMIC	0.010	Loss
Other_Aur_AurB_ST	Q09666	AHNAK	Q96GD4	AURKB	S3483	P3480L	3480	Missense	distal	-3	no	0.010	0.011	EPSD	COSMIC	0.010	Up-regulation
Other_Aur_AurB_ST	Q09666	AHNAK	Q96GD4	AURKB	S3874	A3870T	3870	Missense	distal	-4	no	0.011	0.010	EPSD	COSMIC	0.010	Down-regulation
Other_Aur_AurB_ST	Q09666	AHNAK	Q96GD4	AURKB	S3874	K3872N	3872	Missense	proximal	-2	no	0.011	-0.001	EPSD	COSMIC	0.010	Loss
Other_Aur_AurB_ST	Q09666	AHNAK	Q96GD4	AURKB	S4460	S4460C	4460	Missense	central	0	yes	0.010	0.000	EPSD	COSMIC	0.010	Loss
Other_Aur_AurB_ST	Q09666	AHNAK	Q96GD4	AURKB	S4661	K4659N	4659	Missense	proximal	-2	no	0.010	-0.001	EPSD	COSMIC	0.010	Loss
Other_Aur_AurB_ST	Q09666	AHNAK	Q96GD4	AURKB	S4661	K4659M	4659	Missense	proximal	-2	no	0.010	-0.002	EPSD	COSMIC;GDSC;CCLE	0.010	Loss
Other_Aur_AurB_ST	Q09666	AHNAK	Q96GD4	AURKB	S4722	S4722F	4722	Missense	central	0	yes	0.011	0.000	EPSD	COSMIC	0.010	Loss
Other_Aur_AurB_ST	Q09666	AHNAK	Q96GD4	AURKB	S5298	S5298C	5298	Missense	central	0	yes	0.010	0.000	EPSD	COSMIC	0.010	Loss
Other_Aur_AurB_ST	Q09666	AHNAK	Q96GD4	AURKB	S5448	R5446W	5446	Missense	proximal	-2	no	0.071	0.002	EPSD	COSMIC	0.010	Loss
Other_Aur_AurB_ST	Q09666	AHNAK	Q96GD4	AURKB	S5448	P5445S	5445	Missense	distal	-3	no	0.071	0.072	EPSD	COSMIC	0.010	Up-regulation
Other_Aur_AurB_ST	Q09666	AHNAK	Q96GD4	AURKB	S5464	V5461A	5461	Missense	distal	-3	no	0.012	0.013	EPSD	COSMIC;GDSC;CCLE	0.010	Up-regulation
Other_Aur_AurB_ST	Q09666	AHNAK	Q96GD4	AURKB	S5780	R5779C	5779	Missense	proximal	-1	no	0.016	0.009	EPSD	COSMIC	0.010	Loss
Other_Aur_AurB_ST	O76021	RSL1D1	Q96GD4	AURKB	S4	E2K	2	Missense	proximal	-2	no	-0.002	0.011	EPSD	COSMIC	0.010	Gain
Other_Aur_AurB_ST	O76021	RSL1D1	Q96GD4	AURKB	T17	G16R	16	Missense	proximal	-1	no	0.002	0.010	EPSD	COSMIC	0.010	Gain
Other_Aur_AurB_ST	O76021	RSL1D1	Q96GD4	AURKB	S18	G16R	16	Missense	proximal	-2	no	0.000	0.072	EPSD	COSMIC	0.010	Gain
Other_Aur_AurB_ST	O76021	RSL1D1	Q96GD4	AURKB	T375	K374N	374	Missense	proximal	-1	no	0.010	0.009	EPSD	COSMIC	0.010	Loss
Other_Aur_AurB_ST	O76021	RSL1D1	Q96GD4	AURKB	S443	E441K	441	Missense	proximal	-2	no	-0.002	0.012	EPSD	COSMIC	0.010	Gain
Other_Aur_AurB_ST	O76021	RSL1D1	Q96GD4	AURKB	S474	V470A	470	Missense	distal	-4	no	0.019	0.020	EPSD	COSMIC	0.010	Up-regulation
Other_Aur_AurB_ST	O76021	RSL1D1	Q96GD4	AURKB	S474	P481H	481	Missense	distal	7	no	0.019	0.020	EPSD	COSMIC	0.010	Up-regulation
AGC_RSK_RSKp90_RPS6KA2_ST	Q15349	RPS6KA2	Q15349	RPS6KA2	S28	E35K	35	Missense	distal	7	no	14.826	14.744	EPSD	COSMIC	8.741	Down-regulation
AGC_RSK_RSKp90_RPS6KA2_ST	Q15349	RPS6KA2	Q15349	RPS6KA2	S28	E35Q	35	Missense	distal	7	no	14.826	14.824	EPSD	COSMIC	8.741	Down-regulation
AGC_RSK_RSKp90_RPS6KA2_ST	Q15349	RPS6KA2	Q15349	RPS6KA2	S30	V37I	37	Missense	distal	7	no	11.018	11.286	EPSD	COSMIC	8.741	Up-regulation
AGC_RSK_RSKp90_RPS6KA2_ST	Q15349	RPS6KA2	Q15349	RPS6KA2	S30	E35K	35	Missense	distal	5	no	11.018	11.078	EPSD	COSMIC	8.741	Up-regulation
AGC_RSK_RSKp90_RPS6KA2_ST	Q15349	RPS6KA2	Q15349	RPS6KA2	S30	E35Q	35	Missense	distal	5	no	11.018	11.014	EPSD	COSMIC	8.741	Down-regulation
AGC_RSK_RSKp90_RPS6KA2_ST	Q15349	RPS6KA2	Q15349	RPS6KA2	S106	R101W	101	Missense	distal	-5	no	11.860	9.968	EPSD	COSMIC;GDSC;CCLE	8.741	Down-regulation
AGC_RSK_RSKp90_RPS6KA2_ST	Q15349	RPS6KA2	Q15349	RPS6KA2	S106	L113S	113	Missense	distal	7	no	11.860	11.489	EPSD	COSMIC	8.741	Down-regulation
AGC_RSK_RSKp90_RPS6KA2_ST	Q15349	RPS6KA2	Q15349	RPS6KA2	S106	M108I	108	Missense	proximal	2	no	11.860	11.673	EPSD	COSMIC	8.741	Down-regulation
AGC_RSK_RSKp90_RPS6KA2_ST	Q15349	RPS6KA2	Q15349	RPS6KA2	S106	R103Q	103	Missense	distal	-3	no	11.860	5.675	EPSD	COSMIC	8.741	Loss
AGC_RSK_RSKp90_RPS6KA2_ST	Q15349	RPS6KA2	Q15349	RPS6KA2	S106	R110K	110	Missense	distal	4	no	11.860	11.859	EPSD	COSMIC	8.741	Down-regulation
AGC_RSK_RSKp90_RPS6KA2_ST	Q15349	RPS6KA2	Q15349	RPS6KA2	S106	K107R	107	Missense	proximal	1	no	11.860	11.866	EPSD	COSMIC	8.741	Up-regulation
AGC_RSK_RSKp90_RPS6KA2_ST	Q15349	RPS6KA2	Q15349	RPS6KA2	S106	R103L	103	Missense	distal	-3	no	11.860	4.990	EPSD	COSMIC	8.741	Loss
AGC_RSK_RSKp90_RPS6KA2_ST	Q15349	RPS6KA2	Q15349	RPS6KA2	S106	R105K	105	Missense	proximal	-1	no	11.860	12.121	EPSD	COSMIC	8.741	Up-regulation
AGC_RSK_RSKp90_RPS6KA2_ST	Q15349	RPS6KA2	Q15349	RPS6KA2	S106	R101L	101	Missense	distal	-5	no	11.860	9.640	EPSD	COSMIC	8.741	Down-regulation
AGC_RSK_RSKp90_RPS6KA2_ST	Q15349	RPS6KA2	Q15349	RPS6KA2	S106	E109D	109	Missense	distal	3	no	11.860	11.919	EPSD	COSMIC	8.741	Up-regulation
AGC_RSK_RSKp90_RPS6KA2_ST	Q15349	RPS6KA2	Q15349	RPS6KA2	S218	D213N	213	Missense	distal	-5	no	14.082	13.471	EPSD;PhosphoSitePlus	COSMIC	8.741	Down-regulation
AGC_RSK_RSKp90_RPS6KA2_ST	Q15349	RPS6KA2	Q15349	RPS6KA2	S218	A216V	216	Missense	proximal	-2	no	14.082	14.105	EPSD;PhosphoSitePlus	COSMIC	8.741	Up-regulation
AGC_RSK_RSKp90_RPS6KA2_ST	Q15349	RPS6KA2	Q15349	RPS6KA2	S218	E224K	224	Missense	distal	6	no	14.082	14.326	EPSD;PhosphoSitePlus	COSMIC	8.741	Up-regulation
AGC_RSK_RSKp90_RPS6KA2_ST	Q15349	RPS6KA2	Q15349	RPS6KA2	S218	T222M	222	Missense	distal	4	no	14.082	14.084	EPSD;PhosphoSitePlus	COSMIC	8.741	Up-regulation
AGC_RSK_RSKp90_RPS6KA2_ST	Q15349	RPS6KA2	Q15349	RPS6KA2	S377	H370Y	370	Missense	distal	-7	no	11.248	11.200	EPSD	COSMIC	8.741	Down-regulation
AGC_RSK_RSKp90_RPS6KA2_ST	Q15349	RPS6KA2	Q15349	RPS6KA2	S377	R374K	374	Missense	distal	-3	no	11.248	7.251	EPSD	COSMIC	8.741	Loss
AGC_RSK_RSKp90_RPS6KA2_ST	Q15349	RPS6KA2	Q15349	RPS6KA2	S377	G375E	375	Missense	proximal	-2	no	11.248	11.307	EPSD	COSMIC	8.741	Up-regulation
AGC_RSK_RSKp90_RPS6KA2_ST	Q15349	RPS6KA2	Q15349	RPS6KA2	S544	G545V	545	Missense	proximal	1	no	14.088	14.139	EPSD	COSMIC	8.741	Up-regulation
AGC_RSK_RSKp90_RPS6KA2_ST	Q15349	RPS6KA2	Q15349	RPS6KA2	S544	R551Q	551	Missense	distal	7	no	14.088	14.166	EPSD	COSMIC	8.741	Up-regulation
AGC_RSK_RSKp90_RPS6KA2_ST	Q15349	RPS6KA2	Q15349	RPS6KA2	S544	E543K	543	Missense	proximal	-1	no	14.088	14.099	EPSD	COSMIC	8.741	Up-regulation
AGC_RSK_RSKp90_RPS6KA2_ST	Q15349	RPS6KA2	Q15349	RPS6KA2	S544	S544L	544	Missense	central	0	yes	14.088	0.000	EPSD	COSMIC	8.741	Loss
AGC_RSK_RSKp90_RPS6KA2_ST	Q15349	RPS6KA2	Q15349	RPS6KA2	S544	S546C	546	Missense	proximal	2	no	14.088	13.055	EPSD	COSMIC;GDSC	8.741	Down-regulation
AGC_RSK_RSKp90_RPS6KA2_ST	Q15349	RPS6KA2	Q15349	RPS6KA2	S546	E543K	543	Missense	distal	-3	no	6.697	10.105	EPSD	COSMIC	8.741	Gain
AGC_RSK_RSKp90_RPS6KA2_ST	Q15349	RPS6KA2	Q15349	RPS6KA2	S628	S628F	628	Missense	central	0	yes	13.109	0.000	EPSD	COSMIC	8.741	Loss
AGC_RSK_RSKp90_RPS6KA2_ST	Q15349	RPS6KA2	Q15349	RPS6KA2	S628	L633I	633	Missense	distal	5	no	13.109	13.103	EPSD	COSMIC	8.741	Down-regulation
AGC_RSK_RSKp90_RPS6KA2_ST	Q15349	RPS6KA2	Q15349	RPS6KA2	S628	I626F	626	Missense	proximal	-2	no	13.109	13.105	EPSD	COSMIC	8.741	Down-regulation
AGC_RSK_RSKp90_RPS6KA2_ST	Q15349	RPS6KA2	Q15349	RPS6KA2	S628	A624V	624	Missense	distal	-4	no	13.109	13.023	EPSD	COSMIC	8.741	Down-regulation
AGC_RSK_RSKp90_RPS6KA2_ST	Q15349	RPS6KA2	Q15349	RPS6KA2	S628	L633F	633	Missense	distal	5	no	13.109	13.097	EPSD	COSMIC	8.741	Down-regulation
AGC_RSK_RSKp90_RPS6KA2_ST	Q15349	RPS6KA2	Q15349	RPS6KA2	S730	R732Q	732	Missense	proximal	2	no	14.483	14.462	EPSD	COSMIC	8.741	Down-regulation
AGC_RSK_RSKp90_RPS6KA2_ST	Q15349	RPS6KA2	Q15349	RPS6KA2	S730	T731M	731	Missense	proximal	1	no	14.483	14.468	EPSD	COSMIC	8.741	Down-regulation
AGC_RSK_RSKp90_RPS6KA2_ST	Q15349	RPS6KA2	Q15349	RPS6KA2	S730	T729M	729	Missense	proximal	-1	no	14.483	14.602	EPSD	COSMIC	8.741	Up-regulation
AGC_RSK_RSKp90_RPS6KA2_ST	P16220	CREB1	Q15349	RPS6KA2	S98	S103N	103	Missense	distal	5	no	12.951	12.751	EPSD	COSMIC	8.741	Down-regulation
AGC_RSK_RSKp90_RPS6KA2_ST	P16220	CREB1	Q15349	RPS6KA2	S98	R95I	95	Missense	distal	-3	no	12.951	3.580	EPSD	COSMIC	8.741	Loss
AGC_RSK_RSKp90_RPS6KA2_ST	P16220	CREB1	Q15349	RPS6KA2	S98	I102M	102	Missense	distal	4	no	12.951	12.945	EPSD	COSMIC	8.741	Down-regulation
AGC_RSK_RSKp90_RPS6KA2_ST	P16220	CREB1	Q15349	RPS6KA2	S121	V118L	118	Missense	distal	-3	no	5.698	9.469	EPSD	COSMIC	8.741	Gain
AGC_RSK_RSKp90_RPS6KA2_ST	P16220	CREB1	Q15349	RPS6KA2	S133	L128R	128	Missense	distal	-5	no	13.505	15.725	PhosphoSitePlus	COSMIC	8.741	Up-regulation
TK_Src_SrcB_BLK_Y	P31995	FCGR2C	P51451	BLK	Y287	G292S	292	Missense	distal	5	no	2.085	2.074	EPSD	COSMIC	0.806	Down-regulation
TK_Src_SrcB_BLK_Y	P31995	FCGR2C	P51451	BLK	Y294	G292S	292	Missense	proximal	-2	no	2.143	2.106	EPSD	COSMIC	0.806	Down-regulation
TK_Src_SrcB_BLK_Y	P31995	FCGR2C	P51451	BLK	Y310	D304N	304	Missense	distal	-6	no	2.007	1.968	PhosphoSitePlus	COSMIC	0.806	Down-regulation
TK_Src_SrcB_BLK_Y	P31995	FCGR2C	P51451	BLK	Y310	P314L	314	Missense	distal	4	no	2.007	1.951	PhosphoSitePlus	COSMIC	0.806	Down-regulation
TK_Src_SrcB_BLK_Y	P12318	FCGR2A	P51451	BLK	Y281	T277I	277	Missense	distal	-4	no	2.051	2.004	EPSD	COSMIC	0.806	Down-regulation
TK_Src_SrcB_BLK_Y	P12318	FCGR2A	P51451	BLK	Y281	G286D	286	Missense	distal	5	no	2.051	2.036	EPSD	COSMIC	0.806	Down-regulation
TK_Src_SrcB_BLK_Y	P12318	FCGR2A	P51451	BLK	Y281	G286S	286	Missense	distal	5	no	2.051	2.040	EPSD	COSMIC;CCLE	0.806	Down-regulation
TK_Src_SrcB_BLK_Y	P12318	FCGR2A	P51451	BLK	Y288	G286D	286	Missense	proximal	-2	no	2.162	2.136	EPSD;PhosphoSitePlus	COSMIC	0.806	Down-regulation
TK_Src_SrcB_BLK_Y	P12318	FCGR2A	P51451	BLK	Y288	G286S	286	Missense	proximal	-2	no	2.162	2.125	EPSD;PhosphoSitePlus	COSMIC;CCLE	0.806	Down-regulation
TK_Src_SrcB_BLK_Y	P12318	FCGR2A	P51451	BLK	Y304	P309S	309	Missense	distal	5	no	1.972	2.000	PhosphoSitePlus;EPSD	COSMIC	0.806	Up-regulation
TK_Src_SrcB_BLK_Y	P31994	FCGR2B	P51451	BLK	Y292	P298Q	298	Missense	distal	6	no	2.045	2.074	PhosphoSitePlus	COSMIC	0.806	Up-regulation
Other_NEK_NEK2_NEK2_ST	Q8N137	CNTROB	P51955	NEK2	S41	A48V	48	Missense	distal	7	no	2.982	2.923	EPSD;PhosphoSitePlus	COSMIC	1.575	Down-regulation
Other_NEK_NEK2_NEK2_ST	Q8N137	CNTROB	P51955	NEK2	S45	A50T	50	Missense	distal	5	no	3.154	3.126	EPSD;PhosphoSitePlus	COSMIC	1.575	Down-regulation
Other_NEK_NEK2_NEK2_ST	Q8N137	CNTROB	P51955	NEK2	S45	A48V	48	Missense	distal	3	no	3.154	3.176	EPSD;PhosphoSitePlus	COSMIC	1.575	Up-regulation
Other_NEK_NEK2_NEK2_ST	Q8N137	CNTROB	P51955	NEK2	S171	R168H	168	Missense	distal	-3	no	0.404	1.611	EPSD	COSMIC	1.575	Gain
Other_NEK_NEK2_NEK2_ST	Q8N137	CNTROB	P51955	NEK2	T570	L568I	568	Missense	proximal	-2	no	1.684	1.775	EPSD	COSMIC;GDSC;CCLE	1.575	Up-regulation
Other_NEK_NEK2_NEK2_ST	Q8N137	CNTROB	P51955	NEK2	T571	L568I	568	Missense	distal	-3	no	1.685	1.049	EPSD	COSMIC;GDSC;CCLE	1.575	Loss
Other_NEK_NEK2_NEK2_ST	Q8N137	CNTROB	P51955	NEK2	S769	R772Q	772	Missense	distal	3	no	1.748	1.764	EPSD	COSMIC;GDSC	1.575	Up-regulation
Other_NEK_NEK2_NEK2_ST	Q8N137	CNTROB	P51955	NEK2	S769	M766V	766	Missense	distal	-3	no	1.748	1.369	EPSD	COSMIC	1.575	Loss
Other_NEK_NEK2_NEK2_ST	Q8N137	CNTROB	P51955	NEK2	S769	P776S	776	Missense	distal	7	no	1.748	1.754	EPSD	COSMIC	1.575	Up-regulation
Other_NEK_NEK2_NEK2_ST	Q8N137	CNTROB	P51955	NEK2	S769	S768P	768	Missense	proximal	-1	no	1.748	1.771	EPSD	COSMIC	1.575	Up-regulation
Other_NEK_NEK2_NEK2_ST	Q8N137	CNTROB	P51955	NEK2	S781	G785C	785	Missense	distal	4	no	1.599	1.642	EPSD	COSMIC	1.575	Up-regulation
Other_NEK_NEK2_NEK2_ST	Q8N137	CNTROB	P51955	NEK2	S781	P776S	776	Missense	distal	-5	no	1.599	1.550	EPSD	COSMIC	1.575	Loss
Other_NEK_NEK2_NEK2_ST	P51955	NEK2	P51955	NEK2	T170	F176C	176	Missense	distal	6	no	2.885	2.976	EPSD;PhosphoSitePlus	COSMIC	1.575	Up-regulation
Other_NEK_NEK2_NEK2_ST	P51955	NEK2	P51955	NEK2	S171	F176C	176	Missense	distal	5	no	3.034	2.955	EPSD;PhosphoSitePlus	COSMIC	1.575	Down-regulation
Other_NEK_NEK2_NEK2_ST	P51955	NEK2	P51955	NEK2	T175	F176C	176	Missense	proximal	1	no	3.241	3.252	EPSD;PhosphoSitePlus	COSMIC	1.575	Up-regulation
Other_NEK_NEK2_NEK2_ST	P51955	NEK2	P51955	NEK2	T179	F176C	176	Missense	distal	-3	no	3.148	2.139	EPSD;PhosphoSitePlus	COSMIC	1.575	Down-regulation
Other_NEK_NEK2_NEK2_ST	P51955	NEK2	P51955	NEK2	S241	R239C	239	Missense	proximal	-2	no	3.396	3.170	PhosphoSitePlus;EPSD	COSMIC	1.575	Down-regulation
Other_NEK_NEK2_NEK2_ST	P51955	NEK2	P51955	NEK2	S241	P237L	237	Missense	distal	-4	no	3.396	3.334	PhosphoSitePlus;EPSD	COSMIC	1.575	Down-regulation
Other_NEK_NEK2_NEK2_ST	P51955	NEK2	P51955	NEK2	S241	R239G	239	Missense	proximal	-2	no	3.396	3.043	PhosphoSitePlus;EPSD	COSMIC	1.575	Down-regulation
Other_NEK_NEK2_NEK2_ST	P51955	NEK2	P51955	NEK2	S356	R361W	361	Missense	distal	5	no	2.945	2.920	EPSD;PhosphoSitePlus	COSMIC;GDSC;CCLE	1.575	Down-regulation
Other_NEK_NEK2_NEK2_ST	P51955	NEK2	P51955	NEK2	S356	K353M	353	Missense	distal	-3	no	2.945	2.645	EPSD;PhosphoSitePlus	COSMIC;CCLE	1.575	Down-regulation
Other_NEK_NEK2_NEK2_ST	P51955	NEK2	P51955	NEK2	S397	N393S	393	Missense	distal	-4	no	3.078	3.068	EPSD;PhosphoSitePlus	COSMIC	1.575	Down-regulation
Other_NEK_NEK2_NEK2_ST	P51955	NEK2	P51955	NEK2	S402	T405I	405	Missense	distal	3	no	3.147	3.173	EPSD;PhosphoSitePlus	COSMIC	1.575	Up-regulation
Other_NEK_NEK2_NEK2_ST	P51955	NEK2	P51955	NEK2	S428	Q435K	435	Missense	distal	7	no	1.977	2.042	EPSD;PhosphoSitePlus	COSMIC	1.575	Up-regulation
Other_NEK_NEK2_NEK2_ST	P51955	NEK2	P51955	NEK2	S428	R423L	423	Missense	distal	-5	no	1.977	1.904	EPSD;PhosphoSitePlus	COSMIC	1.575	Down-regulation
Other_NEK_NEK2_NEK2_ST	P36873	PPP1CC	P51955	NEK2	T307	T311M	311	Missense	distal	4	no	2.056	2.223	PhosphoSitePlus;EPSD	COSMIC	1.575	Up-regulation
Other_NEK_NEK2_NEK2_ST	P36873	PPP1CC	P51955	NEK2	T307	E300D	300	Missense	distal	-7	no	2.056	1.954	PhosphoSitePlus;EPSD	COSMIC	1.575	Down-regulation
Other_NEK_NEK2_NEK2_ST	P36873	PPP1CC	P51955	NEK2	T307	A306S	306	Missense	proximal	-1	no	2.056	2.126	PhosphoSitePlus;EPSD	COSMIC	1.575	Up-regulation
Other_NEK_NEK2_NEK2_ST	P36873	PPP1CC	P51955	NEK2	T318	T311M	311	Missense	distal	-7	no	1.930	2.181	EPSD;PhosphoSitePlus	COSMIC	1.575	Up-regulation
Other_NEK_NEK2_NEK2_ST	P36873	PPP1CC	P51955	NEK2	T318	G315S	315	Missense	distal	-3	no	1.930	1.792	EPSD;PhosphoSitePlus	COSMIC	1.575	Down-regulation
Other_NEK_NEK2_NEK2_ST	P36873	PPP1CC	P51955	NEK2	T318	K322N	322	Missense	distal	4	no	1.930	1.660	EPSD;PhosphoSitePlus	COSMIC	1.575	Down-regulation
Other_NEK_NEK2_NEK2_ST	Q9H2D6	TRIOBP	P51955	NEK2	S279	P276F	276	Missense	distal	-3	no	0.508	1.767	EPSD	COSMIC	1.575	Gain
Other_NEK_NEK2_NEK2_ST	Q9H2D6	TRIOBP	P51955	NEK2	T594	N597S	597	Missense	distal	3	no	2.002	2.068	EPSD	COSMIC	1.575	Up-regulation
Other_NEK_NEK2_NEK2_ST	Q9H2D6	TRIOBP	P51955	NEK2	T594	T594A	594	Missense	central	0	yes	2.002	0.000	EPSD	COSMIC	1.575	Loss
Other_NEK_NEK2_NEK2_ST	Q9H2D6	TRIOBP	P51955	NEK2	T594	N591S	591	Missense	distal	-3	no	2.002	1.651	EPSD	COSMIC	1.575	Down-regulation
Other_NEK_NEK2_NEK2_ST	Q9H2D6	TRIOBP	P51955	NEK2	T594	R595Q	595	Missense	proximal	1	no	2.002	1.937	EPSD	COSMIC	1.575	Down-regulation
Other_NEK_NEK2_NEK2_ST	Q9H2D6	TRIOBP	P51955	NEK2	T594	P590R	590	Missense	distal	-4	no	2.002	1.921	EPSD	COSMIC	1.575	Down-regulation
Other_NEK_NEK2_NEK2_ST	Q9H2D6	TRIOBP	P51955	NEK2	T594	P598L	598	Missense	distal	4	no	2.002	1.985	EPSD	COSMIC	1.575	Down-regulation
Other_NEK_NEK2_NEK2_ST	Q9H2D6	TRIOBP	P51955	NEK2	T642	P639F	639	Missense	distal	-3	no	1.383	2.642	EPSD	COSMIC	1.575	Gain
Other_NEK_NEK2_NEK2_ST	Q9H2D6	TRIOBP	P51955	NEK2	T714	N712S	712	Missense	proximal	-2	no	1.575	1.344	EPSD	COSMIC	1.575	Loss
Other_NEK_NEK2_NEK2_ST	Q9H2D6	TRIOBP	P51955	NEK2	T714	P711L	711	Missense	distal	-3	no	1.575	2.402	EPSD	COSMIC	1.575	Up-regulation
Other_NEK_NEK2_NEK2_ST	Q9H2D6	TRIOBP	P51955	NEK2	T714	P720S	720	Missense	distal	6	no	1.575	1.498	EPSD	COSMIC	1.575	Loss
Other_NEK_NEK2_NEK2_ST	Q9H2D6	TRIOBP	P51955	NEK2	T714	S710Y	710	Missense	distal	-4	no	1.575	1.473	EPSD	COSMIC	1.575	Loss
Other_NEK_NEK2_NEK2_ST	Q9H2D6	TRIOBP	P51955	NEK2	T715	N712S	712	Missense	distal	-3	no	1.934	1.582	EPSD	COSMIC	1.575	Down-regulation
Other_NEK_NEK2_NEK2_ST	Q9H2D6	TRIOBP	P51955	NEK2	T715	P711L	711	Missense	distal	-4	no	1.934	1.871	EPSD	COSMIC	1.575	Down-regulation
Other_NEK_NEK2_NEK2_ST	Q9H2D6	TRIOBP	P51955	NEK2	T715	P720S	720	Missense	distal	5	no	1.934	1.821	EPSD	COSMIC	1.575	Down-regulation
Other_NEK_NEK2_NEK2_ST	Q9H2D6	TRIOBP	P51955	NEK2	T715	S710Y	710	Missense	distal	-5	no	1.934	1.973	EPSD	COSMIC	1.575	Up-regulation
Other_NEK_NEK2_NEK2_ST	Q9H2D6	TRIOBP	P51955	NEK2	T817	D813N	813	Missense	distal	-4	no	2.398	2.435	EPSD	COSMIC	1.575	Up-regulation
Other_NEK_NEK2_NEK2_ST	Q9H2D6	TRIOBP	P51955	NEK2	T817	I823N	823	Missense	distal	6	no	2.398	2.282	EPSD	COSMIC	1.575	Down-regulation
Other_NEK_NEK2_NEK2_ST	Q9H2D6	TRIOBP	P51955	NEK2	T817	N814H	814	Missense	distal	-3	no	2.398	2.743	EPSD	COSMIC	1.575	Up-regulation
Other_NEK_NEK2_NEK2_ST	Q9H2D6	TRIOBP	P51955	NEK2	S895	Q888E	888	Missense	distal	-7	no	1.687	1.838	EPSD	COSMIC	1.575	Up-regulation
Other_NEK_NEK2_NEK2_ST	Q9H2D6	TRIOBP	P51955	NEK2	S923	S916N	916	Missense	distal	-7	no	2.266	2.718	EPSD	COSMIC	1.575	Up-regulation
Other_NEK_NEK2_NEK2_ST	Q9H2D6	TRIOBP	P51955	NEK2	S923	S916T	916	Missense	distal	-7	no	2.266	2.406	EPSD	COSMIC	1.575	Up-regulation
Other_NEK_NEK2_NEK2_ST	Q9H2D6	TRIOBP	P51955	NEK2	S923	R926H	926	Missense	distal	3	no	2.266	2.410	EPSD	COSMIC	1.575	Up-regulation
Other_NEK_NEK2_NEK2_ST	Q9H2D6	TRIOBP	P51955	NEK2	S923	Q929R	929	Missense	distal	6	no	2.266	2.151	EPSD	COSMIC	1.575	Down-regulation
Other_NEK_NEK2_NEK2_ST	Q9H2D6	TRIOBP	P51955	NEK2	S923	R926C	926	Missense	distal	3	no	2.266	2.352	EPSD	COSMIC;GDSC	1.575	Up-regulation
Other_NEK_NEK2_NEK2_ST	Q9H2D6	TRIOBP	P51955	NEK2	S1235	P1230H	1230	Missense	distal	-5	no	2.033	2.032	EPSD	COSMIC	1.575	Down-regulation
Other_NEK_NEK2_NEK2_ST	Q9H2D6	TRIOBP	P51955	NEK2	S1235	P1233L	1233	Missense	proximal	-2	no	2.033	2.030	EPSD	COSMIC;CCLE	1.575	Down-regulation
Other_NEK_NEK2_NEK2_ST	Q9H2D6	TRIOBP	P51955	NEK2	T1684	L1687M	1687	Missense	distal	3	no	2.990	2.993	EPSD	COSMIC	1.575	Up-regulation
Other_NEK_NEK2_NEK2_ST	Q9H2D6	TRIOBP	P51955	NEK2	T1684	G1688R	1688	Missense	distal	4	no	2.990	3.133	EPSD	COSMIC	1.575	Up-regulation
Other_NEK_NEK2_NEK2_ST	Q9H2D6	TRIOBP	P51955	NEK2	T1684	G1688W	1688	Missense	distal	4	no	2.990	3.008	EPSD	COSMIC	1.575	Up-regulation
Other_NEK_NEK2_NEK2_ST	Q9H2D6	TRIOBP	P51955	NEK2	T1961	D1967N	1967	Missense	distal	6	no	1.633	1.446	EPSD	COSMIC	1.575	Loss
Other_NEK_NEK2_NEK2_ST	Q9H2D6	TRIOBP	P51955	NEK2	T1961	Q1957K	1957	Missense	distal	-4	no	1.633	1.678	EPSD	COSMIC	1.575	Up-regulation
Other_NEK_NEK2_NEK2_ST	Q9H2D6	TRIOBP	P51955	NEK2	T1961	R1958L	1958	Missense	distal	-3	no	1.633	2.784	EPSD	COSMIC	1.575	Up-regulation
Other_NEK_NEK2_NEK2_ST	Q9H2D6	TRIOBP	P51955	NEK2	T1961	P1956L	1956	Missense	distal	-5	no	1.633	1.620	EPSD	COSMIC	1.575	Down-regulation
Other_NEK_NEK2_NEK2_ST	Q9H2D6	TRIOBP	P51955	NEK2	T1993	R1986Q	1986	Missense	distal	-7	no	3.137	3.134	EPSD	COSMIC	1.575	Down-regulation
Other_NEK_NEK2_NEK2_ST	Q9H2D6	TRIOBP	P51955	NEK2	S2175	L2170P	2170	Missense	distal	-5	no	1.901	1.913	EPSD	COSMIC	1.575	Up-regulation
Other_NEK_NEK2_NEK2_ST	Q92997	DVL3	P51955	NEK2	T135	D130Y	130	Missense	distal	-5	no	1.636	1.586	EPSD	COSMIC;GDSC;CCLE	1.575	Down-regulation
Other_NEK_NEK2_NEK2_ST	Q92997	DVL3	P51955	NEK2	T135	Q142L	142	Missense	distal	7	no	1.636	1.638	EPSD	COSMIC;GDSC;CCLE	1.575	Up-regulation
Other_NEK_NEK2_NEK2_ST	Q92997	DVL3	P51955	NEK2	T135	T135R	135	Missense	central	0	yes	1.636	0.000	EPSD	COSMIC	1.575	Loss
Other_NEK_NEK2_NEK2_ST	Q92997	DVL3	P51955	NEK2	T135	S137Y	137	Missense	proximal	2	no	1.636	1.711	EPSD	COSMIC	1.575	Up-regulation
Other_NEK_NEK2_NEK2_ST	Q92997	DVL3	P51955	NEK2	S280	K283N	283	Missense	distal	3	no	2.946	2.858	EPSD;PhosphoSitePlus	COSMIC	1.575	Down-regulation
Other_NEK_NEK2_NEK2_ST	Q92997	DVL3	P51955	NEK2	S280	G275S	275	Missense	distal	-5	no	2.946	2.874	EPSD;PhosphoSitePlus	COSMIC	1.575	Down-regulation
Other_NEK_NEK2_NEK2_ST	Q92997	DVL3	P51955	NEK2	S697	R702C	702	Missense	distal	5	no	1.985	1.963	EPSD;PhosphoSitePlus	COSMIC	1.575	Down-regulation
Other_NEK_NEK2_NEK2_ST	Q92997	DVL3	P51955	NEK2	S697	P691L	691	Missense	distal	-6	no	1.985	1.987	EPSD;PhosphoSitePlus	COSMIC	1.575	Up-regulation
Other_NEK_NEK2_NEK2_ST	P54274	TERF1	P51955	NEK2	S249	S242R	242	Missense	distal	-7	no	2.333	2.270	EPSD	COSMIC	1.575	Down-regulation
Other_NEK_NEK2_NEK2_ST	P54274	TERF1	P51955	NEK2	S249	S252L	252	Missense	distal	3	no	2.333	2.392	EPSD	COSMIC	1.575	Up-regulation
Other_NEK_NEK2_NEK2_ST	P54274	TERF1	P51955	NEK2	S404	L408F	408	Missense	distal	4	no	1.480	1.583	EPSD	COSMIC	1.575	Gain
Other_NEK_NEK2_NEK2_ST	Q9BV73	CEP250	P51955	NEK2	T933	Q936H	936	Missense	distal	3	no	1.608	1.735	EPSD	COSMIC	1.575	Up-regulation
Other_NEK_NEK2_NEK2_ST	Q9BV73	CEP250	P51955	NEK2	S1927	R1922W	1922	Missense	distal	-5	no	1.960	1.938	EPSD	COSMIC	1.575	Down-regulation
Other_NEK_NEK2_NEK2_ST	Q9BV73	CEP250	P51955	NEK2	S1927	A1931V	1931	Missense	distal	4	no	1.960	1.970	EPSD	COSMIC	1.575	Up-regulation
Other_NEK_NEK2_NEK2_ST	Q9BV73	CEP250	P51955	NEK2	S1927	Q1930R	1930	Missense	distal	3	no	1.960	1.944	EPSD	COSMIC	1.575	Down-regulation
Other_NEK_NEK2_NEK2_ST	Q9BV73	CEP250	P51955	NEK2	S1927	L1924P	1924	Missense	distal	-3	no	1.960	1.134	EPSD	COSMIC	1.575	Loss
Other_NEK_NEK2_NEK2_ST	Q9BV73	CEP250	P51955	NEK2	S1927	Q1932K	1932	Missense	distal	5	no	1.960	2.119	EPSD	COSMIC	1.575	Up-regulation
Other_NEK_NEK2_NEK2_ST	Q9BV73	CEP250	P51955	NEK2	T2218	R2220W	2220	Missense	proximal	2	no	1.717	1.736	EPSD	COSMIC;CCLE	1.575	Up-regulation
Other_NEK_NEK2_NEK2_ST	Q9BV73	CEP250	P51955	NEK2	T2405	V2398M	2398	Missense	distal	-7	no	1.183	1.581	EPSD	COSMIC	1.575	Gain
Other_NEK_NEK2_NEK2_ST	Q9BV73	CEP250	P51955	NEK2	S2417	R2413K	2413	Missense	distal	-4	no	2.004	1.983	PhosphoSitePlus;EPSD	COSMIC	1.575	Down-regulation
Other_NEK_NEK2_NEK2_ST	P06748	NPM1	P51955	NEK2	S70	G69D	69	Missense	proximal	-1	no	3.055	2.726	PhosphoSitePlus;EPSD	COSMIC;GDSC;CCLE	1.575	Down-regulation
Other_NEK_NEK2_NEK2_ST	P06748	NPM1	P51955	NEK2	S243	A249G	249	Missense	distal	6	no	1.455	1.606	EPSD	COSMIC	1.575	Gain
Other_NEK_NEK2_NEK2_ST	P06748	NPM1	P51955	NEK2	S260	I255V	255	Missense	distal	-5	no	1.629	1.622	EPSD	COSMIC	1.575	Down-regulation
Other_NEK_NEK2_NEK2_ST	P06748	NPM1	P51955	NEK2	S260	K263E	263	Missense	distal	3	no	1.629	1.568	EPSD	COSMIC	1.575	Loss
Other_NEK_NEK2_NEK2_ST	P06748	NPM1	P51955	NEK2	S260	L261F	261	Missense	proximal	1	no	1.629	1.632	EPSD	COSMIC	1.575	Up-regulation
Other_NEK_NEK2_NEK2_ST	P06748	NPM1	P51955	NEK2	S260	S260C	260	Missense	central	0	yes	1.629	0.000	EPSD	COSMIC	1.575	Loss
Other_NEK_NEK2_NEK2_ST	Q5FBB7	SGO1	P51955	NEK2	S14	S14R	14	Missense	central	0	yes	2.279	0.000	PhosphoSitePlus;EPSD	COSMIC	1.575	Loss
Other_NEK_NEK2_NEK2_ST	Q5FBB7	SGO1	P51955	NEK2	T264	Q261H	261	Missense	distal	-3	no	1.513	2.310	EPSD	COSMIC	1.575	Gain
Other_NEK_NEK2_NEK2_ST	Q5FBB7	SGO1	P51955	NEK2	T268	Q261H	261	Missense	distal	-7	no	1.320	1.577	EPSD	COSMIC	1.575	Gain
Other_NEK_NEK2_NEK2_ST	Q5FBB7	SGO1	P51955	NEK2	S394	T393R	393	Missense	proximal	-1	no	1.498	1.788	EPSD	COSMIC	1.575	Gain
Other_NEK_NEK2_NEK2_ST	Q5FBB7	SGO1	P51955	NEK2	T417	D413N	413	Missense	distal	-4	no	1.725	1.762	EPSD	COSMIC	1.575	Up-regulation
Other_NEK_NEK2_NEK2_ST	Q5FBB7	SGO1	P51955	NEK2	T417	E418Q	418	Missense	proximal	1	no	1.725	1.713	EPSD	COSMIC	1.575	Down-regulation
Other_NEK_NEK2_NEK2_ST	Q5FBB7	SGO1	P51955	NEK2	T417	E418G	418	Missense	proximal	1	no	1.725	1.683	EPSD	COSMIC	1.575	Down-regulation
Other_NEK_NEK2_NEK2_ST	Q5FBB7	SGO1	P51955	NEK2	T423	E418Q	418	Missense	distal	-5	no	1.527	1.586	EPSD	COSMIC	1.575	Gain
Other_NEK_NEK2_NEK2_ST	Q5FBB7	SGO1	P51955	NEK2	T445	V452L	452	Missense	distal	7	no	1.733	1.734	EPSD	COSMIC	1.575	Up-regulation
Other_NEK_NEK2_NEK2_ST	Q5FBB7	SGO1	P51955	NEK2	T445	S448F	448	Missense	distal	3	no	1.733	1.720	EPSD	COSMIC	1.575	Down-regulation
Other_NEK_NEK2_NEK2_ST	Q5FBB7	SGO1	P51955	NEK2	T445	Y450C	450	Missense	distal	5	no	1.733	1.695	EPSD	COSMIC	1.575	Down-regulation
Other_NEK_NEK2_NEK2_ST	Q5FBB7	SGO1	P51955	NEK2	T445	D443N	443	Missense	proximal	-2	no	1.733	1.865	EPSD	COSMIC	1.575	Up-regulation
Other_NEK_NEK2_NEK2_ST	Q5FBB7	SGO1	P51955	NEK2	T445	L441P	441	Missense	distal	-4	no	1.733	1.795	EPSD	COSMIC	1.575	Up-regulation
Other_NEK_NEK2_NEK2_ST	Q5FBB7	SGO1	P51955	NEK2	T488	Y484C	484	Missense	distal	-4	no	1.821	1.827	EPSD	COSMIC	1.575	Up-regulation
Other_NEK_NEK2_NEK2_ST	Q5FBB7	SGO1	P51955	NEK2	T488	L489F	489	Missense	proximal	1	no	1.821	1.825	EPSD	COSMIC	1.575	Up-regulation
Other_NEK_NEK2_NEK2_ST	Q5FBB7	SGO1	P51955	NEK2	T488	A490V	490	Missense	proximal	2	no	1.821	2.042	EPSD	COSMIC	1.575	Up-regulation
Other_NEK_NEK2_NEK2_ST	Q5FBB7	SGO1	P51955	NEK2	T488	S491L	491	Missense	distal	3	no	1.821	1.880	EPSD	COSMIC	1.575	Up-regulation
Other_NEK_NEK2_NEK2_ST	Q5FBB7	SGO1	P51955	NEK2	S507	S507Y	507	Missense	central	0	yes	3.034	0.000	EPSD;PhosphoSitePlus	COSMIC	1.575	Loss
Other_NEK_NEK2_NEK2_ST	P13639	EEF2	P51955	NEK2	S279	S274C	274	Missense	distal	-5	no	1.616	1.678	EPSD	COSMIC	1.575	Up-regulation
Other_NEK_NEK2_NEK2_ST	P13639	EEF2	P51955	NEK2	T423	G424D	424	Missense	proximal	1	no	2.317	2.372	EPSD	COSMIC	1.575	Up-regulation
Other_NEK_NEK2_NEK2_ST	P13639	EEF2	P51955	NEK2	T482	K481N	481	Missense	proximal	-1	no	1.585	1.548	EPSD	COSMIC	1.575	Loss
Other_NEK_NEK2_NEK2_ST	P13639	EEF2	P51955	NEK2	T482	L479Q	479	Missense	distal	-3	no	1.585	0.844	EPSD	COSMIC;GDSC;CCLE	1.575	Loss
Other_NEK_NEK2_NEK2_ST	P13639	EEF2	P51955	NEK2	T482	D476H	476	Missense	distal	-6	no	1.585	1.584	EPSD	COSMIC	1.575	Down-regulation
Other_NEK_NEK2_NEK2_ST	P13639	EEF2	P51955	NEK2	S502	A508V	508	Missense	distal	6	no	1.449	1.624	EPSD	COSMIC	1.575	Gain
Other_NEK_NEK2_NEK2_ST	P13639	EEF2	P51955	NEK2	T582	P575Q	575	Missense	distal	-7	no	1.751	2.023	EPSD	COSMIC	1.575	Up-regulation
Other_NEK_NEK2_NEK2_ST	P13639	EEF2	P51955	NEK2	S595	H599R	599	Missense	distal	4	no	2.095	1.967	PhosphoSitePlus	COSMIC	1.575	Down-regulation
Other_NEK_NEK2_NEK2_ST	P13639	EEF2	P51955	NEK2	S732	R727H	727	Missense	distal	-5	no	1.725	1.665	EPSD	COSMIC	1.575	Down-regulation
Other_NEK_NEK2_NEK2_ST	P13639	EEF2	P51955	NEK2	S793	P789L	789	Missense	distal	-4	no	1.634	1.572	EPSD	COSMIC	1.575	Loss
Other_NEK_NEK2_NEK2_ST	P13639	EEF2	P51955	NEK2	S793	E792K	792	Missense	proximal	-1	no	1.634	1.434	EPSD	COSMIC;GDSC;CCLE	1.575	Loss
Other_NEK_NEK2_NEK2_ST	O15360	FANCA	P51955	NEK2	S73	G66C	66	Missense	distal	-7	no	1.394	1.754	EPSD	COSMIC	1.575	Gain
Other_NEK_NEK2_NEK2_ST	O15360	FANCA	P51955	NEK2	S303	T306M	306	Missense	distal	3	no	1.556	1.686	EPSD	COSMIC	1.575	Gain
Other_NEK_NEK2_NEK2_ST	O15360	FANCA	P51955	NEK2	T323	T323I	323	Missense	central	0	yes	1.658	0.000	EPSD	COSMIC	1.575	Loss
Other_NEK_NEK2_NEK2_ST	O15360	FANCA	P51955	NEK2	T351	R350Q	350	Missense	proximal	-1	no	3.148	2.766	PhosphoSitePlus	COSMIC;GDSC	1.575	Down-regulation
Other_NEK_NEK2_NEK2_ST	O15360	FANCA	P51955	NEK2	T351	S357L	357	Missense	distal	6	no	3.148	3.198	PhosphoSitePlus	COSMIC	1.575	Up-regulation
Other_NEK_NEK2_NEK2_ST	O15360	FANCA	P51955	NEK2	T351	W346C	346	Missense	distal	-5	no	3.148	3.123	PhosphoSitePlus	COSMIC	1.575	Down-regulation
Other_NEK_NEK2_NEK2_ST	O15360	FANCA	P51955	NEK2	T351	L355F	355	Missense	distal	4	no	3.148	3.252	PhosphoSitePlus	COSMIC	1.575	Up-regulation
Other_NEK_NEK2_NEK2_ST	O15360	FANCA	P51955	NEK2	S357	R350Q	350	Missense	distal	-7	no	1.604	1.600	EPSD	COSMIC;GDSC	1.575	Down-regulation
Other_NEK_NEK2_NEK2_ST	O15360	FANCA	P51955	NEK2	S357	S357L	357	Missense	central	0	yes	1.604	0.000	EPSD	COSMIC	1.575	Loss
Other_NEK_NEK2_NEK2_ST	O15360	FANCA	P51955	NEK2	S357	R360H	360	Missense	distal	3	no	1.604	1.747	EPSD	COSMIC;CCLE	1.575	Up-regulation
Other_NEK_NEK2_NEK2_ST	O15360	FANCA	P51955	NEK2	S357	L355F	355	Missense	proximal	-2	no	1.604	1.532	EPSD	COSMIC	1.575	Loss
Other_NEK_NEK2_NEK2_ST	O15360	FANCA	P51955	NEK2	S1217	A1219V	1219	Missense	proximal	2	no	1.528	1.749	EPSD	COSMIC	1.575	Gain
Other_NEK_NEK2_NEK2_ST	O15360	FANCA	P51955	NEK2	T1309	D1312Y	1312	Missense	distal	3	no	1.774	1.940	EPSD	COSMIC	1.575	Up-regulation
Other_NEK_NEK2_NEK2_ST	O15360	FANCA	P51955	NEK2	T1309	R1314G	1314	Missense	distal	5	no	1.774	1.766	EPSD	COSMIC	1.575	Down-regulation
Other_NEK_NEK2_NEK2_ST	O14777	NDC80	P51955	NEK2	S77	I73L	73	Missense	distal	-4	no	1.618	1.621	EPSD	COSMIC	1.575	Up-regulation
Other_NEK_NEK2_NEK2_ST	O14777	NDC80	P51955	NEK2	S165	A163T	163	Missense	proximal	-2	no	4.351	4.404	PhosphoSitePlus	COSMIC	1.575	Up-regulation
Other_NEK_NEK2_NEK2_ST	Q96CN5	LRRC45	P51955	NEK2	T328	E324V	324	Missense	distal	-4	no	1.661	1.440	EPSD	COSMIC	1.575	Loss
Other_NEK_NEK2_NEK2_ST	Q96CN5	LRRC45	P51955	NEK2	S399	E403A	403	Missense	distal	4	no	1.751	1.628	EPSD	COSMIC	1.575	Down-regulation
Other_NEK_NEK2_NEK2_ST	P04637	TP53	P51955	NEK2	S46	M40I	40	Missense	distal	-6	no	2.017	2.019	EPSD	COSMIC	1.575	Up-regulation
Other_NEK_NEK2_NEK2_ST	P04637	TP53	P51955	NEK2	S46	W53C	53	Missense	distal	7	no	2.017	2.048	EPSD	COSMIC	1.575	Up-regulation
Other_NEK_NEK2_NEK2_ST	P04637	TP53	P51955	NEK2	S46	W53G	53	Missense	distal	7	no	2.017	2.003	EPSD	COSMIC	1.575	Down-regulation
Other_NEK_NEK2_NEK2_ST	P04637	TP53	P51955	NEK2	S46	S46F	46	Missense	central	0	yes	2.017	0.000	EPSD	COSMIC	1.575	Loss
Other_NEK_NEK2_NEK2_ST	P04637	TP53	P51955	NEK2	S46	D49Y	49	Missense	distal	3	no	2.017	2.183	EPSD	COSMIC	1.575	Up-regulation
Other_NEK_NEK2_NEK2_ST	P04637	TP53	P51955	NEK2	S46	P47L	47	Missense	proximal	1	no	2.017	2.007	EPSD	COSMIC	1.575	Down-regulation
Other_NEK_NEK2_NEK2_ST	P04637	TP53	P51955	NEK2	S46	D49H	49	Missense	distal	3	no	2.017	2.184	EPSD	COSMIC;GDSC;CCLE	1.575	Up-regulation
Other_NEK_NEK2_NEK2_ST	P04637	TP53	P51955	NEK2	S46	P47S	47	Missense	proximal	1	no	2.017	1.970	EPSD	COSMIC	1.575	Down-regulation
Other_NEK_NEK2_NEK2_ST	P04637	TP53	P51955	NEK2	S46	D41N	41	Missense	distal	-5	no	2.017	1.972	EPSD	COSMIC	1.575	Down-regulation
Other_NEK_NEK2_NEK2_ST	P04637	TP53	P51955	NEK2	S46	D48H	48	Missense	proximal	2	no	2.017	1.881	EPSD	COSMIC	1.575	Down-regulation
Other_NEK_NEK2_NEK2_ST	P04637	TP53	P51955	NEK2	S46	D49N	49	Missense	distal	3	no	2.017	2.120	EPSD	COSMIC	1.575	Up-regulation
Other_NEK_NEK2_NEK2_ST	P04637	TP53	P51955	NEK2	S46	M44I	44	Missense	proximal	-2	no	2.017	1.593	EPSD	COSMIC	1.575	Down-regulation
Other_NEK_NEK2_NEK2_ST	P04637	TP53	P51955	NEK2	S46	Q52H	52	Missense	distal	6	no	2.017	1.696	EPSD	COSMIC	1.575	Down-regulation
Other_NEK_NEK2_NEK2_ST	P04637	TP53	P51955	NEK2	S46	D49V	49	Missense	distal	3	no	2.017	2.168	EPSD	COSMIC	1.575	Up-regulation
Other_NEK_NEK2_NEK2_ST	P04637	TP53	P51955	NEK2	S46	A39V	39	Missense	distal	-7	no	2.017	1.908	EPSD	COSMIC	1.575	Down-regulation
Other_NEK_NEK2_NEK2_ST	P04637	TP53	P51955	NEK2	S46	A39S	39	Missense	distal	-7	no	2.017	1.915	EPSD	COSMIC	1.575	Down-regulation
Other_NEK_NEK2_NEK2_ST	P04637	TP53	P51955	NEK2	S46	D42Y	42	Missense	distal	-4	no	2.017	1.942	EPSD	COSMIC	1.575	Down-regulation
Other_NEK_NEK2_NEK2_ST	P04637	TP53	P51955	NEK2	S46	M44R	44	Missense	proximal	-2	no	2.017	1.729	EPSD	COSMIC	1.575	Down-regulation
Other_NEK_NEK2_NEK2_ST	P04637	TP53	P51955	NEK2	S46	S46P	46	Missense	central	0	yes	2.017	0.000	EPSD	COSMIC	1.575	Loss
Other_NEK_NEK2_NEK2_ST	P04637	TP53	P51955	NEK2	S46	M44V	44	Missense	proximal	-2	no	2.017	1.675	EPSD	COSMIC	1.575	Down-regulation
Other_NEK_NEK2_NEK2_ST	P04637	TP53	P51955	NEK2	S46	L45P	45	Missense	proximal	-1	no	2.017	2.031	EPSD	COSMIC	1.575	Up-regulation
Other_NEK_NEK2_NEK2_ST	P04637	TP53	P51955	NEK2	S46	M44T	44	Missense	proximal	-2	no	2.017	1.777	EPSD	COSMIC	1.575	Down-regulation
Other_NEK_NEK2_NEK2_ST	P04637	TP53	P51955	NEK2	S46	A39T	39	Missense	distal	-7	no	2.017	2.055	EPSD	COSMIC	1.575	Up-regulation
Other_NEK_NEK2_NEK2_ST	P04637	TP53	P51955	NEK2	S46	L43F	43	Missense	distal	-3	no	2.017	2.450	EPSD	COSMIC	1.575	Up-regulation
Other_NEK_NEK2_NEK2_ST	P04637	TP53	P51955	NEK2	S46	D41H	41	Missense	distal	-5	no	2.017	1.977	EPSD	COSMIC	1.575	Down-regulation
Other_NEK_NEK2_NEK2_ST	P04637	TP53	P51955	NEK2	S46	D49E	49	Missense	distal	3	no	2.017	2.148	EPSD	COSMIC	1.575	Up-regulation
Other_NEK_NEK2_NEK2_ST	P04637	TP53	P51955	NEK2	S46	D49G	49	Missense	distal	3	no	2.017	2.138	EPSD	COSMIC	1.575	Up-regulation
Other_NEK_NEK2_NEK2_ST	P04637	TP53	P51955	NEK2	S46	D48A	48	Missense	proximal	2	no	2.017	1.959	EPSD	COSMIC	1.575	Down-regulation
Other_NEK_NEK2_NEK2_ST	P04637	TP53	P51955	NEK2	S46	D48Y	48	Missense	proximal	2	no	2.017	2.129	EPSD	COSMIC	1.575	Up-regulation
Other_NEK_NEK2_NEK2_ST	P04637	TP53	P51955	NEK2	S46	D48E	48	Missense	proximal	2	no	2.017	2.057	EPSD	COSMIC	1.575	Up-regulation
Other_NEK_NEK2_NEK2_ST	P04637	TP53	P51955	NEK2	S46	D49I	49	Missense	distal	3	no	2.017	2.144	EPSD	COSMIC	1.575	Up-regulation
Other_NEK_NEK2_NEK2_ST	P04637	TP53	P51955	NEK2	S46	D41E	41	Missense	distal	-5	no	2.017	1.958	EPSD	COSMIC	1.575	Down-regulation
Other_NEK_NEK2_NEK2_ST	P04637	TP53	P51955	NEK2	S99	S96F	96	Missense	distal	-3	no	0.968	2.041	EPSD	COSMIC	1.575	Gain
Other_NEK_NEK2_NEK2_ST	P04637	TP53	P51955	NEK2	S99	S96Y	96	Missense	distal	-3	no	0.968	1.974	EPSD	COSMIC	1.575	Gain
Other_NEK_NEK2_NEK2_ST	P04637	TP53	P51955	NEK2	S106	R110H	110	Missense	distal	4	no	1.544	1.672	EPSD	COSMIC	1.575	Gain
Other_NEK_NEK2_NEK2_ST	P04637	TP53	P51955	NEK2	S106	T102I	102	Missense	distal	-4	no	1.544	1.598	EPSD	COSMIC	1.575	Gain
Other_NEK_NEK2_NEK2_ST	P04637	TP53	P51955	NEK2	S106	K101R	101	Missense	distal	-5	no	1.544	1.659	EPSD	COSMIC	1.575	Gain
Other_NEK_NEK2_NEK2_ST	P04637	TP53	P51955	NEK2	S106	T102P	102	Missense	distal	-4	no	1.544	1.664	EPSD	COSMIC	1.575	Gain
Other_NEK_NEK2_NEK2_ST	P04637	TP53	P51955	NEK2	S106	L111M	111	Missense	distal	5	no	1.544	1.746	EPSD	COSMIC	1.575	Gain
Other_NEK_NEK2_NEK2_ST	P04637	TP53	P51955	NEK2	S106	Q104H	104	Missense	proximal	-2	no	1.544	1.582	EPSD	COSMIC	1.575	Gain
Other_NEK_NEK2_NEK2_ST	P04637	TP53	P51955	NEK2	S106	K101N	101	Missense	distal	-5	no	1.544	1.594	EPSD	COSMIC	1.575	Gain
Other_NEK_NEK2_NEK2_ST	P04637	TP53	P51955	NEK2	S106	R110S	110	Missense	distal	4	no	1.544	1.600	EPSD	COSMIC	1.575	Gain
Other_NEK_NEK2_NEK2_ST	P04637	TP53	P51955	NEK2	S106	G112D	112	Missense	distal	6	no	1.544	1.715	EPSD	COSMIC	1.575	Gain
Other_NEK_NEK2_NEK2_ST	P04637	TP53	P51955	NEK2	S106	G112R	112	Missense	distal	6	no	1.544	1.605	EPSD	COSMIC	1.575	Gain
Other_NEK_NEK2_NEK2_ST	P04637	TP53	P51955	NEK2	T125	C124W	124	Missense	proximal	-1	no	1.654	1.663	EPSD	COSMIC	1.575	Up-regulation
Other_NEK_NEK2_NEK2_ST	P04637	TP53	P51955	NEK2	T125	C124F	124	Missense	proximal	-1	no	1.654	1.602	EPSD	COSMIC	1.575	Down-regulation
Other_NEK_NEK2_NEK2_ST	P04637	TP53	P51955	NEK2	T125	C124S	124	Missense	proximal	-1	no	1.654	1.532	EPSD	COSMIC	1.575	Loss
Other_NEK_NEK2_NEK2_ST	P04637	TP53	P51955	NEK2	T125	S127A	127	Missense	proximal	2	no	1.654	1.559	EPSD	COSMIC	1.575	Loss
Other_NEK_NEK2_NEK2_ST	P04637	TP53	P51955	NEK2	T125	S127L	127	Missense	proximal	2	no	1.654	1.626	EPSD	COSMIC	1.575	Down-regulation
Other_NEK_NEK2_NEK2_ST	P04637	TP53	P51955	NEK2	T125	C124T	124	Missense	proximal	-1	no	1.654	1.508	EPSD	COSMIC	1.575	Loss
Other_NEK_NEK2_NEK2_ST	P04637	TP53	P51955	NEK2	T125	S127I	127	Missense	proximal	2	no	1.654	1.676	EPSD	COSMIC	1.575	Up-regulation
Other_NEK_NEK2_NEK2_ST	P04637	TP53	P51955	NEK2	T125	S127G	127	Missense	proximal	2	no	1.654	1.735	EPSD	COSMIC	1.575	Up-regulation
Other_NEK_NEK2_NEK2_ST	P04637	TP53	P51955	NEK2	T125	N131H	131	Missense	distal	6	no	1.654	1.526	EPSD	COSMIC	1.575	Loss
Other_NEK_NEK2_NEK2_ST	P04637	TP53	P51955	NEK2	T125	N131D	131	Missense	distal	6	no	1.654	1.841	EPSD	COSMIC	1.575	Up-regulation
Other_NEK_NEK2_NEK2_ST	P04637	TP53	P51955	NEK2	T125	T125I	125	Missense	central	0	yes	1.654	0.000	EPSD	COSMIC	1.575	Loss
Other_NEK_NEK2_NEK2_ST	P04637	TP53	P51955	NEK2	T125	K120T	120	Missense	distal	-5	no	1.654	1.702	EPSD	COSMIC	1.575	Up-regulation
Other_NEK_NEK2_NEK2_ST	P04637	TP53	P51955	NEK2	T125	T125K	125	Missense	central	0	yes	1.654	0.000	EPSD	COSMIC	1.575	Loss
Other_NEK_NEK2_NEK2_ST	P04637	TP53	P51955	NEK2	T125	N131K	131	Missense	distal	6	no	1.654	1.519	EPSD	COSMIC;CCLE	1.575	Loss
Other_NEK_NEK2_NEK2_ST	P04637	TP53	P51955	NEK2	T125	T118I	118	Missense	distal	-7	no	1.654	1.503	EPSD	COSMIC	1.575	Loss
Other_NEK_NEK2_NEK2_ST	P04637	TP53	P51955	NEK2	T125	P128S	128	Missense	distal	3	no	1.654	1.620	EPSD	COSMIC	1.575	Down-regulation
Other_NEK_NEK2_NEK2_ST	P04637	TP53	P51955	NEK2	T125	A129T	129	Missense	distal	4	no	1.654	1.704	EPSD	COSMIC	1.575	Up-regulation
Other_NEK_NEK2_NEK2_ST	P04637	TP53	P51955	NEK2	T125	T123I	123	Missense	proximal	-2	no	1.654	1.470	EPSD	COSMIC	1.575	Loss
Other_NEK_NEK2_NEK2_ST	P04637	TP53	P51955	NEK2	T125	A129G	129	Missense	distal	4	no	1.654	1.412	EPSD	COSMIC	1.575	Loss
Other_NEK_NEK2_NEK2_ST	P04637	TP53	P51955	NEK2	T125	K132W	132	Missense	distal	7	no	1.654	1.552	EPSD	COSMIC	1.575	Loss
Other_NEK_NEK2_NEK2_ST	P04637	TP53	P51955	NEK2	T125	A129V	129	Missense	distal	4	no	1.654	1.663	EPSD	COSMIC	1.575	Up-regulation
Other_NEK_NEK2_NEK2_ST	P04637	TP53	P51955	NEK2	T125	P128A	128	Missense	distal	3	no	1.654	1.580	EPSD	COSMIC	1.575	Down-regulation
Other_NEK_NEK2_NEK2_ST	P04637	TP53	P51955	NEK2	T125	L130I	130	Missense	distal	5	no	1.654	1.666	EPSD	COSMIC	1.575	Up-regulation
Other_NEK_NEK2_NEK2_ST	P04637	TP53	P51955	NEK2	T125	S121F	121	Missense	distal	-4	no	1.654	1.499	EPSD	COSMIC	1.575	Loss
Other_NEK_NEK2_NEK2_ST	P04637	TP53	P51955	NEK2	T125	A129D	129	Missense	distal	4	no	1.654	1.318	EPSD	COSMIC	1.575	Loss
Other_NEK_NEK2_NEK2_ST	P04637	TP53	P51955	NEK2	T125	T118A	118	Missense	distal	-7	no	1.654	1.616	EPSD	COSMIC	1.575	Down-regulation
Other_NEK_NEK2_NEK2_ST	P04637	TP53	P51955	NEK2	T125	K120Q	120	Missense	distal	-5	no	1.654	1.750	EPSD	COSMIC	1.575	Up-regulation
Other_NEK_NEK2_NEK2_ST	P04637	TP53	P51955	NEK2	T125	A119V	119	Missense	distal	-6	no	1.654	1.656	EPSD	COSMIC	1.575	Up-regulation
Other_NEK_NEK2_NEK2_ST	P04637	TP53	P51955	NEK2	T125	A119D	119	Missense	distal	-6	no	1.654	1.655	EPSD	COSMIC	1.575	Up-regulation
Other_NEK_NEK2_NEK2_ST	P04637	TP53	P51955	NEK2	T125	P128L	128	Missense	distal	3	no	1.654	1.679	EPSD	COSMIC	1.575	Up-regulation
Other_NEK_NEK2_NEK2_ST	P04637	TP53	P51955	NEK2	T125	V122L	122	Missense	distal	-3	no	1.654	2.674	EPSD	COSMIC	1.575	Up-regulation
Other_NEK_NEK2_NEK2_ST	P04637	TP53	P51955	NEK2	T125	T118R	118	Missense	distal	-7	no	1.654	1.451	EPSD	COSMIC	1.575	Loss
Other_NEK_NEK2_NEK2_ST	P04637	TP53	P51955	NEK2	T125	C124L	124	Missense	proximal	-1	no	1.654	1.541	EPSD	COSMIC	1.575	Loss
Other_NEK_NEK2_NEK2_ST	P04637	TP53	P51955	NEK2	T125	N131T	131	Missense	distal	6	no	1.654	1.656	EPSD	COSMIC	1.575	Up-regulation
Other_NEK_NEK2_NEK2_ST	P04637	TP53	P51955	NEK2	T150	V147F	147	Missense	distal	-3	no	0.762	2.215	EPSD	COSMIC	1.575	Gain
Other_NEK_NEK2_NEK2_ST	P04637	TP53	P51955	NEK2	T155	P151N	151	Missense	distal	-4	no	1.836	1.807	EPSD	COSMIC	1.575	Down-regulation
Other_NEK_NEK2_NEK2_ST	P04637	TP53	P51955	NEK2	T155	P152A	152	Missense	distal	-3	no	1.836	1.590	EPSD	COSMIC	1.575	Down-regulation
Other_NEK_NEK2_NEK2_ST	P04637	TP53	P51955	NEK2	T155	P152T	152	Missense	distal	-3	no	1.836	1.579	EPSD	COSMIC	1.575	Down-regulation
Other_NEK_NEK2_NEK2_ST	P04637	TP53	P51955	NEK2	T155	P152H	152	Missense	distal	-3	no	1.836	2.718	EPSD	COSMIC	1.575	Up-regulation
Other_NEK_NEK2_NEK2_ST	P04637	TP53	P51955	NEK2	T155	A159S	159	Missense	distal	4	no	1.836	1.791	EPSD	COSMIC	1.575	Down-regulation
Other_NEK_NEK2_NEK2_ST	P04637	TP53	P51955	NEK2	T155	P153T	153	Missense	proximal	-2	no	1.836	2.108	EPSD	COSMIC	1.575	Up-regulation
Other_NEK_NEK2_NEK2_ST	P04637	TP53	P51955	NEK2	T155	A159T	159	Missense	distal	4	no	1.836	1.885	EPSD	COSMIC	1.575	Up-regulation
Other_NEK_NEK2_NEK2_ST	P04637	TP53	P51955	NEK2	T155	P153L	153	Missense	proximal	-2	no	1.836	1.833	EPSD	COSMIC	1.575	Down-regulation
Other_NEK_NEK2_NEK2_ST	P04637	TP53	P51955	NEK2	T155	S149P	149	Missense	distal	-6	no	1.836	1.835	EPSD	COSMIC	1.575	Down-regulation
Other_NEK_NEK2_NEK2_ST	P04637	TP53	P51955	NEK2	T155	P152K	152	Missense	distal	-3	no	1.836	2.321	EPSD	COSMIC	1.575	Up-regulation
Other_NEK_NEK2_NEK2_ST	P04637	TP53	P51955	NEK2	T155	P153S	153	Missense	proximal	-2	no	1.836	1.826	EPSD	COSMIC	1.575	Down-regulation
Other_NEK_NEK2_NEK2_ST	P04637	TP53	P51955	NEK2	T155	G154C	154	Missense	proximal	-1	no	1.836	1.611	EPSD	COSMIC	1.575	Down-regulation
Other_NEK_NEK2_NEK2_ST	P04637	TP53	P51955	NEK2	T155	G154D	154	Missense	proximal	-1	no	1.836	1.507	EPSD	COSMIC	1.575	Loss
Other_NEK_NEK2_NEK2_ST	P04637	TP53	P51955	NEK2	T155	M160K	160	Missense	distal	5	no	1.836	1.869	EPSD	COSMIC	1.575	Up-regulation
Other_NEK_NEK2_NEK2_ST	P04637	TP53	P51955	NEK2	T155	M160L	160	Missense	distal	5	no	1.836	1.633	EPSD	COSMIC	1.575	Down-regulation
Other_NEK_NEK2_NEK2_ST	P04637	TP53	P51955	NEK2	T155	I162V	162	Missense	distal	7	no	1.836	1.890	EPSD	COSMIC	1.575	Up-regulation
Other_NEK_NEK2_NEK2_ST	P04637	TP53	P51955	NEK2	T155	V157I	157	Missense	proximal	2	no	1.836	1.732	EPSD	COSMIC	1.575	Down-regulation
Other_NEK_NEK2_NEK2_ST	P04637	TP53	P51955	NEK2	T155	A161G	161	Missense	distal	6	no	1.836	1.987	EPSD	COSMIC	1.575	Up-regulation
Other_NEK_NEK2_NEK2_ST	P04637	TP53	P51955	NEK2	T155	D148V	148	Missense	distal	-7	no	1.836	1.845	EPSD	COSMIC	1.575	Up-regulation
Other_NEK_NEK2_NEK2_ST	P04637	TP53	P51955	NEK2	T155	I162M	162	Missense	distal	7	no	1.836	2.006	EPSD	COSMIC	1.575	Up-regulation
Other_NEK_NEK2_NEK2_ST	P04637	TP53	P51955	NEK2	T155	S149Y	149	Missense	distal	-6	no	1.836	1.837	EPSD	COSMIC	1.575	Up-regulation
Other_NEK_NEK2_NEK2_ST	P04637	TP53	P51955	NEK2	T155	M160V	160	Missense	distal	5	no	1.836	1.653	EPSD	COSMIC	1.575	Down-regulation
Other_NEK_NEK2_NEK2_ST	P04637	TP53	P51955	NEK2	T155	A159D	159	Missense	distal	4	no	1.836	1.500	EPSD	COSMIC;GDSC;CCLE	1.575	Loss
Other_NEK_NEK2_NEK2_ST	P04637	TP53	P51955	NEK2	T155	T150I	150	Missense	distal	-5	no	1.836	1.868	EPSD	COSMIC	1.575	Up-regulation
Other_NEK_NEK2_NEK2_ST	P04637	TP53	P51955	NEK2	T155	S149T	149	Missense	distal	-6	no	1.836	1.835	EPSD	COSMIC	1.575	Down-regulation
Other_NEK_NEK2_NEK2_ST	P04637	TP53	P51955	NEK2	T155	R156S	156	Missense	proximal	1	no	1.836	1.722	EPSD	COSMIC	1.575	Down-regulation
Other_NEK_NEK2_NEK2_ST	P04637	TP53	P51955	NEK2	T155	D148E	148	Missense	distal	-7	no	1.836	1.937	EPSD	COSMIC	1.575	Up-regulation
Other_NEK_NEK2_NEK2_ST	P04637	TP53	P51955	NEK2	T155	T155A	155	Missense	central	0	yes	1.836	0.000	EPSD	COSMIC	1.575	Loss
Other_NEK_NEK2_NEK2_ST	P04637	TP53	P51955	NEK2	T155	G154I	154	Missense	proximal	-1	no	1.836	1.468	EPSD	COSMIC	1.575	Loss
Other_NEK_NEK2_NEK2_ST	P04637	TP53	P51955	NEK2	T155	D148G	148	Missense	distal	-7	no	1.836	1.398	EPSD	COSMIC	1.575	Loss
Other_NEK_NEK2_NEK2_ST	P04637	TP53	P51955	NEK2	T155	T150K	150	Missense	distal	-5	no	1.836	1.788	EPSD	COSMIC	1.575	Down-regulation
Other_NEK_NEK2_NEK2_ST	P04637	TP53	P51955	NEK2	T155	P153H	153	Missense	proximal	-2	no	1.836	2.048	EPSD	COSMIC	1.575	Up-regulation
Other_NEK_NEK2_NEK2_ST	P04637	TP53	P51955	NEK2	T155	A161F	161	Missense	distal	6	no	1.836	1.924	EPSD	COSMIC	1.575	Up-regulation
Other_NEK_NEK2_NEK2_ST	P04637	TP53	P51955	NEK2	T155	V157E	157	Missense	proximal	2	no	1.836	1.713	EPSD	COSMIC	1.575	Down-regulation
Other_NEK_NEK2_NEK2_ST	P04637	TP53	P51955	NEK2	T155	D148H	148	Missense	distal	-7	no	1.836	2.043	EPSD	COSMIC	1.575	Up-regulation
Other_NEK_NEK2_NEK2_ST	P04637	TP53	P51955	NEK2	T155	M160T	160	Missense	distal	5	no	1.836	1.756	EPSD	COSMIC	1.575	Down-regulation
Other_NEK_NEK2_NEK2_ST	P04637	TP53	P51955	NEK2	T155	P153A	153	Missense	proximal	-2	no	1.836	2.056	EPSD	COSMIC	1.575	Up-regulation
Other_NEK_NEK2_NEK2_ST	P04637	TP53	P51955	NEK2	T155	T150R	150	Missense	distal	-5	no	1.836	1.903	EPSD	COSMIC	1.575	Up-regulation
Other_NEK_NEK2_NEK2_ST	P04637	TP53	P51955	NEK2	T155	T155L	155	Missense	central	0	yes	1.836	0.000	EPSD	COSMIC	1.575	Loss
Other_NEK_NEK2_NEK2_ST	P04637	TP53	P51955	NEK2	T155	G154A	154	Missense	proximal	-1	no	1.836	1.419	EPSD	COSMIC	1.575	Loss
Other_NEK_NEK2_NEK2_ST	P04637	TP53	P51955	NEK2	T155	T150A	150	Missense	distal	-5	no	1.836	1.805	EPSD	COSMIC	1.575	Down-regulation
Other_NEK_NEK2_NEK2_ST	P04637	TP53	P51955	NEK2	T155	R158F	158	Missense	distal	3	no	1.836	1.969	EPSD	COSMIC	1.575	Up-regulation
Other_NEK_NEK2_NEK2_ST	P04637	TP53	P51955	NEK2	T155	P153F	153	Missense	proximal	-2	no	1.836	1.761	EPSD	COSMIC	1.575	Down-regulation
Other_NEK_NEK2_NEK2_ST	P04637	TP53	P51955	NEK2	T155	A161N	161	Missense	distal	6	no	1.836	1.971	EPSD	COSMIC	1.575	Up-regulation
Other_NEK_NEK2_NEK2_ST	P04637	TP53	P51955	NEK2	T155	G154R	154	Missense	proximal	-1	no	1.836	1.755	EPSD	COSMIC	1.575	Down-regulation
Other_NEK_NEK2_NEK2_ST	P04637	TP53	P51955	NEK2	T211	D208Y	208	Missense	distal	-3	no	0.214	1.872	EPSD	COSMIC	1.575	Gain
Other_NEK_NEK2_NEK2_ST	P04637	TP53	P51955	NEK2	S215	R209Q	209	Missense	distal	-6	no	1.693	1.692	EPSD	COSMIC	1.575	Down-regulation
Other_NEK_NEK2_NEK2_ST	P04637	TP53	P51955	NEK2	S215	R209W	209	Missense	distal	-6	no	1.693	1.694	EPSD	COSMIC	1.575	Up-regulation
Other_NEK_NEK2_NEK2_ST	P04637	TP53	P51955	NEK2	S215	R209L	209	Missense	distal	-6	no	1.693	1.695	EPSD	COSMIC	1.575	Up-regulation
Other_NEK_NEK2_NEK2_ST	P04637	TP53	P51955	NEK2	S215	R209G	209	Missense	distal	-6	no	1.693	1.694	EPSD	COSMIC	1.575	Up-regulation
Other_NEK_NEK2_NEK2_ST	P04637	TP53	P51955	NEK2	S215	R209C	209	Missense	distal	-6	no	1.693	1.694	EPSD	COSMIC	1.575	Up-regulation
Other_NEK_NEK2_NEK2_ST	P04637	TP53	P51955	NEK2	S215	V216A	216	Missense	proximal	1	no	1.693	1.641	EPSD	COSMIC	1.575	Down-regulation
Other_NEK_NEK2_NEK2_ST	P04637	TP53	P51955	NEK2	S215	V217A	217	Missense	proximal	2	no	1.693	1.473	EPSD	COSMIC	1.575	Loss
Other_NEK_NEK2_NEK2_ST	P04637	TP53	P51955	NEK2	S215	P222S	222	Missense	distal	7	no	1.693	1.699	EPSD	COSMIC	1.575	Up-regulation
Other_NEK_NEK2_NEK2_ST	P04637	TP53	P51955	NEK2	S215	P219L	219	Missense	distal	4	no	1.693	1.676	EPSD	COSMIC	1.575	Down-regulation
Other_NEK_NEK2_NEK2_ST	P04637	TP53	P51955	NEK2	S215	V218M	218	Missense	distal	3	no	1.693	1.773	EPSD	COSMIC	1.575	Up-regulation
Other_NEK_NEK2_NEK2_ST	P04637	TP53	P51955	NEK2	S215	D208E	208	Missense	distal	-7	no	1.693	1.795	EPSD	COSMIC	1.575	Up-regulation
Other_NEK_NEK2_NEK2_ST	P04637	TP53	P51955	NEK2	S215	F212L	212	Missense	distal	-3	no	1.693	1.261	EPSD	COSMIC	1.575	Loss
Other_NEK_NEK2_NEK2_ST	P04637	TP53	P51955	NEK2	S215	H214Q	214	Missense	proximal	-1	no	1.693	1.768	EPSD	COSMIC	1.575	Up-regulation
Other_NEK_NEK2_NEK2_ST	P04637	TP53	P51955	NEK2	S215	P219H	219	Missense	distal	4	no	1.693	1.798	EPSD	COSMIC	1.575	Up-regulation
Other_NEK_NEK2_NEK2_ST	P04637	TP53	P51955	NEK2	S215	R213W	213	Missense	proximal	-2	no	1.693	1.472	EPSD	COSMIC	1.575	Loss
Other_NEK_NEK2_NEK2_ST	P04637	TP53	P51955	NEK2	S215	N210D	210	Missense	distal	-5	no	1.693	1.739	EPSD	COSMIC	1.575	Up-regulation
Other_NEK_NEK2_NEK2_ST	P04637	TP53	P51955	NEK2	S215	V218A	218	Missense	distal	3	no	1.693	1.672	EPSD	COSMIC	1.575	Down-regulation
Other_NEK_NEK2_NEK2_ST	P04637	TP53	P51955	NEK2	S215	S215C	215	Missense	central	0	yes	1.693	0.000	EPSD	COSMIC;GDSC;CCLE	1.575	Loss
Other_NEK_NEK2_NEK2_ST	P04637	TP53	P51955	NEK2	S215	V218L	218	Missense	distal	3	no	1.693	1.770	EPSD	COSMIC;GDSC;CCLE	1.575	Up-regulation
Other_NEK_NEK2_NEK2_ST	P04637	TP53	P51955	NEK2	S215	T211N	211	Missense	distal	-4	no	1.693	1.785	EPSD	COSMIC	1.575	Up-regulation
Other_NEK_NEK2_NEK2_ST	P04637	TP53	P51955	NEK2	S215	N210S	210	Missense	distal	-5	no	1.693	1.650	EPSD	COSMIC	1.575	Down-regulation
Other_NEK_NEK2_NEK2_ST	P04637	TP53	P51955	NEK2	S215	P222T	222	Missense	distal	7	no	1.693	1.779	EPSD	COSMIC	1.575	Up-regulation
Other_NEK_NEK2_NEK2_ST	P04637	TP53	P51955	NEK2	S215	F212I	212	Missense	distal	-3	no	1.693	0.625	EPSD	COSMIC	1.575	Loss
Other_NEK_NEK2_NEK2_ST	P04637	TP53	P51955	NEK2	S215	N210H	210	Missense	distal	-5	no	1.693	1.699	EPSD	COSMIC	1.575	Up-regulation
Other_NEK_NEK2_NEK2_ST	P04637	TP53	P51955	NEK2	S215	E221G	221	Missense	distal	6	no	1.693	1.771	EPSD	COSMIC	1.575	Up-regulation
Other_NEK_NEK2_NEK2_ST	P04637	TP53	P51955	NEK2	S215	E221D	221	Missense	distal	6	no	1.693	1.942	EPSD	COSMIC	1.575	Up-regulation
Other_NEK_NEK2_NEK2_ST	P04637	TP53	P51955	NEK2	S215	V217E	217	Missense	proximal	2	no	1.693	1.571	EPSD	COSMIC	1.575	Loss
Other_NEK_NEK2_NEK2_ST	P04637	TP53	P51955	NEK2	S215	R209T	209	Missense	distal	-6	no	1.693	1.692	EPSD	COSMIC	1.575	Down-regulation
Other_NEK_NEK2_NEK2_ST	P04637	TP53	P51955	NEK2	S215	P222L	222	Missense	distal	7	no	1.693	1.735	EPSD	COSMIC	1.575	Up-regulation
Other_NEK_NEK2_NEK2_ST	P04637	TP53	P51955	NEK2	S215	P219R	219	Missense	distal	4	no	1.693	1.670	EPSD	COSMIC	1.575	Down-regulation
Other_NEK_NEK2_NEK2_ST	P04637	TP53	P51955	NEK2	S215	P219S	219	Missense	distal	4	no	1.693	1.726	EPSD	COSMIC	1.575	Up-regulation
Other_NEK_NEK2_NEK2_ST	P04637	TP53	P51955	NEK2	S215	D208Y	208	Missense	distal	-7	no	1.693	1.694	EPSD	COSMIC	1.575	Up-regulation
Other_NEK_NEK2_NEK2_ST	P04637	TP53	P51955	NEK2	S215	P222Q	222	Missense	distal	7	no	1.693	1.733	EPSD	COSMIC	1.575	Up-regulation
Other_NEK_NEK2_NEK2_ST	P04637	TP53	P51955	NEK2	S215	P222A	222	Missense	distal	7	no	1.693	1.793	EPSD	COSMIC	1.575	Up-regulation
Other_NEK_NEK2_NEK2_ST	P04637	TP53	P51955	NEK2	S215	V217L	217	Missense	proximal	2	no	1.693	1.539	EPSD	COSMIC	1.575	Loss
Other_NEK_NEK2_NEK2_ST	P04637	TP53	P51955	NEK2	S215	T211S	211	Missense	distal	-4	no	1.693	1.775	EPSD	COSMIC	1.575	Up-regulation
Other_NEK_NEK2_NEK2_ST	P04637	TP53	P51955	NEK2	S215	D208H	208	Missense	distal	-7	no	1.693	1.901	EPSD	COSMIC	1.575	Up-regulation
Other_NEK_NEK2_NEK2_ST	P04637	TP53	P51955	NEK2	S215	V217M	217	Missense	proximal	2	no	1.693	1.473	EPSD	COSMIC	1.575	Loss
Other_NEK_NEK2_NEK2_ST	P04637	TP53	P51955	NEK2	S215	N210T	210	Missense	distal	-5	no	1.693	1.692	EPSD	COSMIC	1.575	Down-regulation
Other_NEK_NEK2_NEK2_ST	P04637	TP53	P51955	NEK2	S215	N210K	210	Missense	distal	-5	no	1.693	1.643	EPSD	COSMIC	1.575	Down-regulation
Other_NEK_NEK2_NEK2_ST	P04637	TP53	P51955	NEK2	S215	F212S	212	Missense	distal	-3	no	1.693	0.620	EPSD	COSMIC	1.575	Loss
Other_NEK_NEK2_NEK2_ST	P04637	TP53	P51955	NEK2	S215	H214P	214	Missense	proximal	-1	no	1.693	1.908	EPSD	COSMIC	1.575	Up-regulation
Other_NEK_NEK2_NEK2_ST	P04637	TP53	P51955	NEK2	S215	D208I	208	Missense	distal	-7	no	1.693	1.699	EPSD	COSMIC	1.575	Up-regulation
Other_NEK_NEK2_NEK2_ST	P04637	TP53	P51955	NEK2	S215	P219C	219	Missense	distal	4	no	1.693	1.571	EPSD	COSMIC	1.575	Loss
Other_NEK_NEK2_NEK2_ST	P04637	TP53	P51955	NEK2	S215	F212Y	212	Missense	distal	-3	no	1.693	1.626	EPSD	COSMIC	1.575	Down-regulation
Other_NEK_NEK2_NEK2_ST	P04637	TP53	P51955	NEK2	S215	Y220L	220	Missense	distal	5	no	1.693	1.629	EPSD	COSMIC	1.575	Down-regulation
Other_NEK_NEK2_NEK2_ST	P04637	TP53	P51955	NEK2	S215	Y220X	220	Missense	distal	5	no	1.693	1.711	EPSD	COSMIC	1.575	Up-regulation
Other_NEK_NEK2_NEK2_ST	P04637	TP53	P51955	NEK2	S215	H214A	214	Missense	proximal	-1	no	1.693	1.814	EPSD	COSMIC	1.575	Up-regulation
Other_NEK_NEK2_NEK2_ST	P04637	TP53	P51955	NEK2	S269	G262H	262	Missense	distal	-7	no	1.358	2.004	EPSD	COSMIC	1.575	Gain
Other_NEK_NEK2_NEK2_ST	P04637	TP53	P51955	NEK2	S269	G262D	262	Missense	distal	-7	no	1.358	1.797	EPSD	COSMIC;GDSC;CCLE	1.575	Gain
Other_NEK_NEK2_NEK2_ST	P04637	TP53	P51955	NEK2	S269	G262R	262	Missense	distal	-7	no	1.358	1.750	EPSD	COSMIC	1.575	Gain
Other_NEK_NEK2_NEK2_ST	P04637	TP53	P51955	NEK2	S269	N268F	268	Missense	proximal	-1	no	1.358	1.596	EPSD	COSMIC	1.575	Gain
Other_NEK_NEK2_NEK2_ST	P04637	TP53	P51955	NEK2	S269	G262S	262	Missense	distal	-7	no	1.358	1.813	EPSD	COSMIC;GDSC	1.575	Gain
Other_NEK_NEK2_NEK2_ST	P04637	TP53	P51955	NEK2	S313	Q317K	317	Missense	distal	4	no	1.178	1.672	EPSD	COSMIC	1.575	Gain
CAMK_PIM_PIM1_ST	Q13309	SKP2	P11309	PIM1	S34	E31K	31	Missense	distal	-3	no	0.000	0.001	EPSD	COSMIC	0.001	Gain
CAMK_PIM_PIM1_ST	Q13309	SKP2	P11309	PIM1	S72	L70R	70	Missense	proximal	-2	no	0.002	0.003	PhosphoSitePlus;EPSD	COSMIC	0.001	Up-regulation
CAMK_PIM_PIM1_ST	Q13309	SKP2	P11309	PIM1	S75	L70R	70	Missense	distal	-5	no	0.000	0.001	EPSD	COSMIC	0.001	Gain
CAMK_PIM_PIM1_ST	Q96T88	UHRF1	P11309	PIM1	S76	L71R	71	Missense	distal	-5	no	0.000	0.002	EPSD	COSMIC	0.001	Gain
CAMK_PIM_PIM1_ST	Q96T88	UHRF1	P11309	PIM1	S108	E103K	103	Missense	distal	-5	no	0.000	0.001	EPSD	COSMIC	0.001	Gain
CAMK_PIM_PIM1_ST	Q96T88	UHRF1	P11309	PIM1	S119	E116K	116	Missense	distal	-3	no	0.000	0.001	EPSD	COSMIC	0.001	Gain
CAMK_PIM_PIM1_ST	Q96T88	UHRF1	P11309	PIM1	S171	R166Q	166	Missense	distal	-5	no	0.001	0.000	EPSD	COSMIC	0.001	Loss
CAMK_PIM_PIM1_ST	Q96T88	UHRF1	P11309	PIM1	S171	R166L	166	Missense	distal	-5	no	0.001	0.000	EPSD	COSMIC	0.001	Loss
CAMK_PIM_PIM1_ST	Q96T88	UHRF1	P11309	PIM1	S287	R282Q	282	Missense	distal	-5	no	0.001	0.000	EPSD	COSMIC	0.001	Loss
CAMK_PIM_PIM1_ST	Q96T88	UHRF1	P11309	PIM1	S298	R295I	295	Missense	distal	-3	no	0.001	0.000	EPSD	COSMIC	0.001	Loss
CAMK_PIM_PIM1_ST	Q96T88	UHRF1	P11309	PIM1	S298	R295Q	295	Missense	distal	-3	no	0.001	0.000	EPSD	COSMIC	0.001	Loss
CAMK_PIM_PIM1_ST	Q96T88	UHRF1	P11309	PIM1	T411	R406C	406	Missense	distal	-5	no	0.002	0.001	EPSD	COSMIC	0.001	Down-regulation
CAMK_PIM_PIM1_ST	Q96T88	UHRF1	P11309	PIM1	S496	S496C	496	Missense	central	0	yes	0.001	0.000	EPSD	COSMIC	0.001	Loss
CAMK_PIM_PIM1_ST	Q96T88	UHRF1	P11309	PIM1	S639	E634K	634	Missense	distal	-5	no	0.000	0.001	EPSD	COSMIC	0.001	Gain
CAMK_PIM_PIM1_ST	Q96T88	UHRF1	P11309	PIM1	S661	S661F	661	Missense	central	0	yes	0.001	0.000	EPSD	COSMIC	0.001	Loss
CAMK_PIM_PIM1_ST	Q96T88	UHRF1	P11309	PIM1	T665	G660R	660	Missense	distal	-5	no	0.000	0.001	EPSD	COSMIC	0.001	Gain
CAMK_PIM_PIM1_ST	Q96T88	UHRF1	P11309	PIM1	S666	S666F	666	Missense	central	0	yes	0.001	0.000	EPSD	COSMIC	0.001	Loss
CAMK_PIM_PIM1_ST	Q96T88	UHRF1	P11309	PIM1	S707	R704W	704	Missense	distal	-3	no	0.002	0.001	EPSD	COSMIC	0.001	Down-regulation
CAMK_PIM_PIM1_ST	Q96T88	UHRF1	P11309	PIM1	S709	R704W	704	Missense	distal	-5	no	0.001	0.000	EPSD	COSMIC	0.001	Loss
CAMK_PIM_PIM1_ST	Q99683	MAP3K5	P11309	PIM1	S267	K262M	262	Missense	distal	-5	no	0.001	0.000	EPSD	COSMIC	0.001	Loss
CAMK_PIM_PIM1_ST	Q99683	MAP3K5	P11309	PIM1	S461	K458T	458	Missense	distal	-3	no	0.001	0.000	EPSD	COSMIC	0.001	Loss
CAMK_PIM_PIM1_ST	Q99683	MAP3K5	P11309	PIM1	S761	Q756K	756	Missense	distal	-5	no	0.000	0.001	EPSD	COSMIC	0.001	Gain
CAMK_PIM_PIM1_ST	Q99683	MAP3K5	P11309	PIM1	S997	K992I	992	Missense	distal	-5	no	0.001	0.000	EPSD	COSMIC	0.001	Loss
CAMK_PIM_PIM1_ST	Q99683	MAP3K5	P11309	PIM1	T1015	G1012R	1012	Missense	distal	-3	no	0.000	0.001	EPSD	COSMIC	0.001	Gain
CAMK_PIM_PIM1_ST	Q92934	BAD	P11309	PIM1	S97	S97P	97	Missense	central	0	yes	0.001	0.000	EPSD	COSMIC	0.001	Loss
CAMK_PIM_PIM1_ST	Q92934	BAD	P11309	PIM1	S164	R161S	161	Missense	distal	-3	no	0.001	0.000	EPSD	COSMIC;GDSC	0.001	Loss
CAMK_PIM_PIM1_ST	Q92934	BAD	P11309	PIM1	S164	R161G	161	Missense	distal	-3	no	0.001	0.000	EPSD	COSMIC	0.001	Loss
CAMK_PIM_PIM1_ST	P38936	CDKN1A	P11309	PIM1	T97	T97I	97	Missense	central	0	yes	0.001	0.000	EPSD	COSMIC	0.001	Loss
CAMK_PIM_PIM1_ST	P38936	CDKN1A	P11309	PIM1	T145	R143W	143	Missense	proximal	-2	no	0.003	0.002	EPSD;PhosphoSitePlus	COSMIC;GDSC;CCLE	0.001	Down-regulation
CAMK_PIM_PIM1_ST	P38936	CDKN1A	P11309	PIM1	S146	R143W	143	Missense	distal	-3	no	0.002	0.001	PhosphoSitePlus;EPSD	COSMIC;GDSC;CCLE	0.001	Down-regulation
CAMK_PIM_PIM1_ST	P38936	CDKN1A	P11309	PIM1	S160	R155C	155	Missense	distal	-5	no	0.002	0.000	EPSD	COSMIC	0.001	Loss
CAMK_PIM_PIM1_ST	P27448	MARK3	P11309	PIM1	T204	N201K	201	Missense	distal	-3	no	0.000	0.001	EPSD	COSMIC	0.001	Gain
CAMK_PIM_PIM1_ST	P27448	MARK3	P11309	PIM1	T211	T211R	211	Missense	central	0	yes	0.001	0.000	EPSD	COSMIC	0.001	Loss
CAMK_PIM_PIM1_ST	P27448	MARK3	P11309	PIM1	S419	K414Q	414	Missense	distal	-5	no	0.002	0.001	EPSD	COSMIC	0.001	Down-regulation
CAMK_PIM_PIM1_ST	P27448	MARK3	P11309	PIM1	S439	K434E	434	Missense	distal	-5	no	0.001	0.000	EPSD	COSMIC	0.001	Loss
CAMK_PIM_PIM1_ST	P27448	MARK3	P11309	PIM1	S456	R453W	453	Missense	distal	-3	no	0.001	0.000	EPSD	COSMIC;GDSC;CCLE	0.001	Loss
CAMK_PIM_PIM1_ST	P27448	MARK3	P11309	PIM1	S458	R453W	453	Missense	distal	-5	no	0.001	0.000	EPSD	COSMIC;GDSC;CCLE	0.001	Loss
CAMK_PIM_PIM1_ST	P27448	MARK3	P11309	PIM1	S618	R615I	615	Missense	distal	-3	no	0.001	0.000	EPSD	COSMIC	0.001	Loss
CAMK_PIM_PIM1_ST	P27448	MARK3	P11309	PIM1	T627	T627A	627	Missense	central	0	yes	0.001	0.000	EPSD	COSMIC	0.001	Loss
CAMK_PIM_PIM1_ST	P27448	MARK3	P11309	PIM1	S643	R640C	640	Missense	distal	-3	no	0.001	0.000	EPSD	COSMIC	0.001	Loss
CAMK_PIM_PIM1_ST	P27448	MARK3	P11309	PIM1	S734	S734L	734	Missense	central	0	yes	0.002	0.000	EPSD	COSMIC;GDSC	0.001	Loss
CAMK_PIM_PIM1_ST	P27448	MARK3	P11309	PIM1	S734	R729W	729	Missense	distal	-5	no	0.002	0.001	EPSD	COSMIC	0.001	Down-regulation
CAMK_PIM_PIM1_ST	P27448	MARK3	P11309	PIM1	S737	S734L	734	Missense	distal	-3	no	0.001	0.002	EPSD	COSMIC;GDSC	0.001	Up-regulation
CAMK_PIM_PIM1_ST	Q13761	RUNX3	P11309	PIM1	S17	S17F	17	Missense	central	0	yes	0.001	0.000	EPSD	COSMIC	0.001	Loss
CAMK_PIM_PIM1_ST	Q13761	RUNX3	P11309	PIM1	S54	E51Q	51	Missense	distal	-3	no	0.001	0.002	EPSD	COSMIC	0.001	Up-regulation
CAMK_PIM_PIM1_ST	Q13761	RUNX3	P11309	PIM1	S71	R68C	68	Missense	distal	-3	no	0.001	0.000	EPSD	COSMIC	0.001	Loss
CAMK_PIM_PIM1_ST	Q13761	RUNX3	P11309	PIM1	S71	R68H	68	Missense	distal	-3	no	0.001	0.000	EPSD	COSMIC	0.001	Loss
CAMK_PIM_PIM1_ST	Q13761	RUNX3	P11309	PIM1	S144	R139C	139	Missense	distal	-5	no	0.001	0.000	EPSD	COSMIC	0.001	Loss
CAMK_PIM_PIM1_ST	Q13761	RUNX3	P11309	PIM1	S144	S144R	144	Missense	central	0	yes	0.001	0.000	EPSD	COSMIC	0.001	Loss
CAMK_PIM_PIM1_ST	Q13761	RUNX3	P11309	PIM1	S149	R146P	146	Missense	distal	-3	no	0.001	0.000	PhosphoSitePlus;EPSD	COSMIC	0.001	Loss
CAMK_PIM_PIM1_ST	Q13761	RUNX3	P11309	PIM1	S149	S144R	144	Missense	distal	-5	no	0.001	0.002	PhosphoSitePlus;EPSD	COSMIC	0.001	Up-regulation
CAMK_PIM_PIM1_ST	Q13761	RUNX3	P11309	PIM1	T151	K148N	148	Missense	distal	-3	no	0.002	0.001	EPSD;PhosphoSitePlus	COSMIC	0.001	Down-regulation
CAMK_PIM_PIM1_ST	Q13761	RUNX3	P11309	PIM1	T151	R146P	146	Missense	distal	-5	no	0.002	0.001	EPSD;PhosphoSitePlus	COSMIC	0.001	Down-regulation
CAMK_PIM_PIM1_ST	Q13761	RUNX3	P11309	PIM1	T153	K148N	148	Missense	distal	-5	no	0.001	0.000	EPSD;PhosphoSitePlus	COSMIC	0.001	Loss
CAMK_PIM_PIM1_ST	Q13761	RUNX3	P11309	PIM1	T173	R168L	168	Missense	distal	-5	no	0.001	0.000	EPSD	COSMIC	0.001	Loss
CAMK_PIM_PIM1_ST	Q13761	RUNX3	P11309	PIM1	T173	T173I	173	Missense	central	0	yes	0.001	0.000	EPSD	COSMIC;CCLE	0.001	Loss
CAMK_PIM_PIM1_ST	Q13761	RUNX3	P11309	PIM1	T209	R205C	205	Missense	distal	-4	no	0.001	0.000	EPSD	COSMIC	0.001	Loss
CAMK_PIM_PIM1_ST	Q13761	RUNX3	P11309	PIM1	T209	R205H	205	Missense	distal	-4	no	0.001	0.000	EPSD	COSMIC	0.001	Loss
CAMK_PIM_PIM1_ST	Q13761	RUNX3	P11309	PIM1	T221	R216Q	216	Missense	distal	-5	no	0.001	0.000	EPSD	COSMIC	0.001	Loss
CAMK_PIM_PIM1_ST	Q13761	RUNX3	P11309	PIM1	S226	S223R	223	Missense	distal	-3	no	0.000	0.001	EPSD	COSMIC	0.001	Gain
CAMK_PIM_PIM1_ST	Q13761	RUNX3	P11309	PIM1	S237	P232Q	232	Missense	distal	-5	no	0.000	0.001	EPSD	COSMIC	0.001	Gain
CAMK_PIM_PIM1_ST	Q13761	RUNX3	P11309	PIM1	S251	R246C	246	Missense	distal	-5	no	0.001	0.000	EPSD	COSMIC	0.001	Loss
CAMK_PIM_PIM1_ST	Q01860	POU5F1	P11309	PIM1	S180	K177N	177	Missense	distal	-3	no	0.001	0.000	EPSD	COSMIC	0.001	Loss
CAMK_PIM_PIM1_ST	P35568	IRS1	P11309	PIM1	S189	R184C	184	Missense	distal	-5	no	0.001	0.000	EPSD	COSMIC	0.001	Loss
CAMK_PIM_PIM1_ST	P35568	IRS1	P11309	PIM1	S189	S189N	189	Missense	central	0	yes	0.001	0.000	EPSD	COSMIC	0.001	Loss
CAMK_PIM_PIM1_ST	P35568	IRS1	P11309	PIM1	S193	K190N	190	Missense	distal	-3	no	0.001	0.000	EPSD	COSMIC	0.001	Loss
CAMK_PIM_PIM1_ST	P35568	IRS1	P11309	PIM1	S268	R265C	265	Missense	distal	-3	no	0.001	0.000	EPSD	COSMIC	0.001	Loss
CAMK_PIM_PIM1_ST	P35568	IRS1	P11309	PIM1	S270	R265C	265	Missense	distal	-5	no	0.002	0.001	EPSD	COSMIC	0.001	Down-regulation
CAMK_PIM_PIM1_ST	P35568	IRS1	P11309	PIM1	S274	S274P	274	Missense	central	0	yes	0.001	0.000	EPSD	COSMIC	0.001	Loss
CAMK_PIM_PIM1_ST	P35568	IRS1	P11309	PIM1	T305	R302L	302	Missense	distal	-3	no	0.001	0.000	EPSD	COSMIC	0.001	Loss
CAMK_PIM_PIM1_ST	P35568	IRS1	P11309	PIM1	S307	R302L	302	Missense	distal	-5	no	0.002	0.001	EPSD	COSMIC	0.001	Down-regulation
CAMK_PIM_PIM1_ST	P35568	IRS1	P11309	PIM1	T309	E306K	306	Missense	distal	-3	no	0.001	0.002	EPSD	COSMIC	0.001	Up-regulation
CAMK_PIM_PIM1_ST	P35568	IRS1	P11309	PIM1	T311	E306K	306	Missense	distal	-5	no	0.000	0.001	EPSD	COSMIC	0.001	Gain
CAMK_PIM_PIM1_ST	P35568	IRS1	P11309	PIM1	S330	R327L	327	Missense	distal	-3	no	0.002	0.001	EPSD	COSMIC	0.001	Down-regulation
CAMK_PIM_PIM1_ST	P35568	IRS1	P11309	PIM1	S330	R325H	325	Missense	distal	-5	no	0.002	0.001	EPSD	COSMIC;CCLE	0.001	Down-regulation
CAMK_PIM_PIM1_ST	P35568	IRS1	P11309	PIM1	S330	R327C	327	Missense	distal	-3	no	0.002	0.001	EPSD	COSMIC;CCLE	0.001	Down-regulation
CAMK_PIM_PIM1_ST	P35568	IRS1	P11309	PIM1	S330	R325C	325	Missense	distal	-5	no	0.002	0.001	EPSD	COSMIC	0.001	Down-regulation
CAMK_PIM_PIM1_ST	P35568	IRS1	P11309	PIM1	T335	G332R	332	Missense	distal	-3	no	0.000	0.001	EPSD	COSMIC	0.001	Gain
CAMK_PIM_PIM1_ST	P35568	IRS1	P11309	PIM1	S337	G332R	332	Missense	distal	-5	no	0.000	0.001	EPSD	COSMIC	0.001	Gain
CAMK_PIM_PIM1_ST	P35568	IRS1	P11309	PIM1	S341	S341L	341	Missense	central	0	yes	0.001	0.000	EPSD	COSMIC	0.001	Loss
CAMK_PIM_PIM1_ST	P35568	IRS1	P11309	PIM1	S362	R358Q	358	Missense	distal	-4	no	0.001	0.000	EPSD	COSMIC	0.001	Loss
CAMK_PIM_PIM1_ST	P35568	IRS1	P11309	PIM1	S415	S415L	415	Missense	central	0	yes	0.001	0.000	EPSD	COSMIC	0.001	Loss
CAMK_PIM_PIM1_ST	P35568	IRS1	P11309	PIM1	S444	R439Q	439	Missense	distal	-5	no	0.001	0.000	EPSD	COSMIC	0.001	Loss
CAMK_PIM_PIM1_ST	P35568	IRS1	P11309	PIM1	S444	S444I	444	Missense	central	0	yes	0.001	0.000	EPSD	COSMIC	0.001	Loss
CAMK_PIM_PIM1_ST	P35568	IRS1	P11309	PIM1	T446	R443C	443	Missense	distal	-3	no	0.001	0.000	EPSD	COSMIC	0.001	Loss
CAMK_PIM_PIM1_ST	P35568	IRS1	P11309	PIM1	T446	R443L	443	Missense	distal	-3	no	0.001	0.000	EPSD	COSMIC	0.001	Loss
CAMK_PIM_PIM1_ST	P35568	IRS1	P11309	PIM1	S463	E460K	460	Missense	distal	-3	no	0.000	0.001	EPSD	COSMIC	0.001	Gain
CAMK_PIM_PIM1_ST	P35568	IRS1	P11309	PIM1	T525	R520L	520	Missense	distal	-5	no	0.002	0.001	EPSD	COSMIC	0.001	Down-regulation
CAMK_PIM_PIM1_ST	P35568	IRS1	P11309	PIM1	S603	H598R	598	Missense	distal	-5	no	0.001	0.002	EPSD	COSMIC	0.001	Up-regulation
CAMK_PIM_PIM1_ST	P35568	IRS1	P11309	PIM1	S629	R626Q	626	Missense	distal	-3	no	0.001	0.000	EPSD	COSMIC	0.001	Loss
CAMK_PIM_PIM1_ST	P35568	IRS1	P11309	PIM1	S792	S792F	792	Missense	central	0	yes	0.001	0.000	EPSD	COSMIC	0.001	Loss
CAMK_PIM_PIM1_ST	P35568	IRS1	P11309	PIM1	S792	Q787R	787	Missense	distal	-5	no	0.001	0.002	EPSD	COSMIC	0.001	Up-regulation
CAMK_PIM_PIM1_ST	P35568	IRS1	P11309	PIM1	T793	R790C	790	Missense	distal	-3	no	0.001	0.000	EPSD	COSMIC	0.001	Loss
CAMK_PIM_PIM1_ST	P35568	IRS1	P11309	PIM1	S794	S792F	792	Missense	proximal	-2	no	0.000	0.001	EPSD	COSMIC	0.001	Gain
CAMK_PIM_PIM1_ST	P35568	IRS1	P11309	PIM1	S794	Q787R	787	Missense	distal	-7	no	0.000	0.001	EPSD	COSMIC	0.001	Gain
CAMK_PIM_PIM1_ST	P35568	IRS1	P11309	PIM1	S795	R790C	790	Missense	distal	-5	no	0.001	0.000	EPSD	COSMIC	0.001	Loss
CAMK_PIM_PIM1_ST	P35568	IRS1	P11309	PIM1	T847	T847A	847	Missense	central	0	yes	0.001	0.000	EPSD	COSMIC	0.001	Loss
CAMK_PIM_PIM1_ST	P35568	IRS1	P11309	PIM1	T859	T859M	859	Missense	central	0	yes	0.001	0.000	EPSD	COSMIC	0.001	Loss
CAMK_PIM_PIM1_ST	P35568	IRS1	P11309	PIM1	T859	R854L	854	Missense	distal	-5	no	0.001	0.000	EPSD	COSMIC	0.001	Loss
CAMK_PIM_PIM1_ST	P35568	IRS1	P11309	PIM1	S862	R857Q	857	Missense	distal	-5	no	0.001	0.000	EPSD	COSMIC	0.001	Loss
CAMK_PIM_PIM1_ST	P35568	IRS1	P11309	PIM1	S985	S985N	985	Missense	central	0	yes	0.001	0.000	EPSD	COSMIC	0.001	Loss
CAMK_PIM_PIM1_ST	P35568	IRS1	P11309	PIM1	S995	M992K	992	Missense	distal	-3	no	0.000	0.001	EPSD	COSMIC	0.001	Gain
CAMK_PIM_PIM1_ST	P35568	IRS1	P11309	PIM1	S1084	R1081C	1081	Missense	distal	-3	no	0.001	0.000	EPSD	COSMIC	0.001	Loss
CAMK_PIM_PIM1_ST	P35568	IRS1	P11309	PIM1	S1100	R1097W	1097	Missense	distal	-3	no	0.001	0.000	EPSD	COSMIC	0.001	Loss
CAMK_PIM_PIM1_ST	P35568	IRS1	P11309	PIM1	S1101	R1097W	1097	Missense	distal	-4	no	0.003	0.002	PhosphoSitePlus	COSMIC	0.001	Down-regulation
CAMK_PIM_PIM1_ST	P35568	IRS1	P11309	PIM1	S1105	E1102K	1102	Missense	distal	-3	no	0.000	0.001	EPSD	COSMIC	0.001	Gain
CAMK_PIM_PIM1_ST	P35568	IRS1	P11309	PIM1	T1107	E1102K	1102	Missense	distal	-5	no	0.000	0.001	EPSD	COSMIC	0.001	Gain
CAMK_PIM_PIM1_ST	P35568	IRS1	P11309	PIM1	S1143	R1140C	1140	Missense	distal	-3	no	0.001	0.000	EPSD	COSMIC;CCLE	0.001	Loss
CAMK_PIM_PIM1_ST	P35568	IRS1	P11309	PIM1	S1145	R1140C	1140	Missense	distal	-5	no	0.001	0.000	EPSD	COSMIC;CCLE	0.001	Loss
CAMK_PIM_PIM1_ST	P35568	IRS1	P11309	PIM1	S1213	H1208R	1208	Missense	distal	-5	no	0.000	0.001	EPSD	COSMIC	0.001	Gain
CAMK_PIM_PIM1_ST	P35568	IRS1	P11309	PIM1	S1223	R1220C	1220	Missense	distal	-3	no	0.001	0.000	EPSD	COSMIC	0.001	Loss
CAMK_PIM_PIM1_ST	Q00987	MDM2	P11309	PIM1	T47	Q44K	44	Missense	distal	-3	no	0.000	0.001	EPSD	COSMIC	0.001	Gain
CAMK_PIM_PIM1_ST	Q00987	MDM2	P11309	PIM1	T49	Q44K	44	Missense	distal	-5	no	0.000	0.001	EPSD	COSMIC	0.001	Gain
CAMK_PIM_PIM1_ST	Q00987	MDM2	P11309	PIM1	T158	R155T	155	Missense	distal	-3	no	0.001	0.000	EPSD	COSMIC	0.001	Loss
CAMK_PIM_PIM1_ST	Q00987	MDM2	P11309	PIM1	S160	R155T	155	Missense	distal	-5	no	0.001	0.000	EPSD	COSMIC	0.001	Loss
CAMK_PIM_PIM1_ST	Q00987	MDM2	P11309	PIM1	S160	S160F	160	Missense	central	0	yes	0.001	0.000	EPSD	COSMIC	0.001	Loss
CAMK_PIM_PIM1_ST	Q00987	MDM2	P11309	PIM1	S166	S166C	166	Missense	central	0	yes	0.002	0.000	PhosphoSitePlus;EPSD	COSMIC	0.001	Loss
CAMK_PIM_PIM1_ST	Q00987	MDM2	P11309	PIM1	S166	R161T	161	Missense	distal	-5	no	0.002	0.001	PhosphoSitePlus;EPSD	COSMIC	0.001	Down-regulation
CAMK_PIM_PIM1_ST	Q00987	MDM2	P11309	PIM1	S166	S166F	166	Missense	central	0	yes	0.002	0.000	PhosphoSitePlus;EPSD	COSMIC	0.001	Loss
CAMK_PIM_PIM1_ST	Q00987	MDM2	P11309	PIM1	S186	R183H	183	Missense	distal	-3	no	0.003	0.002	EPSD;PhosphoSitePlus	COSMIC	0.001	Down-regulation
CAMK_PIM_PIM1_ST	Q00987	MDM2	P11309	PIM1	S186	R183C	183	Missense	distal	-3	no	0.003	0.002	EPSD;PhosphoSitePlus	COSMIC	0.001	Down-regulation
CAMK_PIM_PIM1_ST	Q00987	MDM2	P11309	PIM1	S186	R179P	179	Missense	distal	-7	no	0.003	0.002	EPSD;PhosphoSitePlus	COSMIC	0.001	Down-regulation
CAMK_PIM_PIM1_ST	Q00987	MDM2	P11309	PIM1	S188	R183H	183	Missense	distal	-5	no	0.002	0.001	EPSD	COSMIC	0.001	Down-regulation
CAMK_PIM_PIM1_ST	Q00987	MDM2	P11309	PIM1	S188	R183C	183	Missense	distal	-5	no	0.002	0.001	EPSD	COSMIC	0.001	Down-regulation
CAMK_PIM_PIM1_ST	Q00987	MDM2	P11309	PIM1	S190	S190F	190	Missense	central	0	yes	0.001	0.000	EPSD	COSMIC	0.001	Loss
CAMK_PIM_PIM1_ST	Q00987	MDM2	P11309	PIM1	S260	E257K	257	Missense	distal	-3	no	0.000	0.001	EPSD	COSMIC	0.001	Gain
CAMK_PIM_PIM1_ST	Q00987	MDM2	P11309	PIM1	S262	E257K	257	Missense	distal	-5	no	0.000	0.001	EPSD	COSMIC	0.001	Gain
CAMK_PIM_PIM1_ST	Q00987	MDM2	P11309	PIM1	T288	E285K	285	Missense	distal	-3	no	0.000	0.001	EPSD	COSMIC	0.001	Gain
CAMK_PIM_PIM1_ST	Q00987	MDM2	P11309	PIM1	S290	E285K	285	Missense	distal	-5	no	0.000	0.001	EPSD	COSMIC	0.001	Gain
CAMK_PIM_PIM1_ST	Q00987	MDM2	P11309	PIM1	S307	S307L	307	Missense	central	0	yes	0.001	0.000	EPSD	COSMIC	0.001	Loss
CAMK_PIM_PIM1_ST	Q00987	MDM2	P11309	PIM1	T419	T419I	419	Missense	central	0	yes	0.001	0.000	EPSD	COSMIC	0.001	Loss
CAMK_PIM_PIM1_ST	Q00987	MDM2	P11309	PIM1	S425	S425C	425	Missense	central	0	yes	0.001	0.000	EPSD	COSMIC	0.001	Loss
CAMK_PIM_PIM1_ST	O43524	FOXO3	P11309	PIM1	T32	R29L	29	Missense	distal	-3	no	0.002	0.001	PhosphoSitePlus;EPSD	COSMIC	0.001	Down-regulation
CAMK_PIM_PIM1_ST	O43524	FOXO3	P11309	PIM1	S253	S253F	253	Missense	central	0	yes	0.002	0.000	EPSD;PhosphoSitePlus	COSMIC	0.001	Loss
CAMK_PIM_PIM1_ST	O43524	FOXO3	P11309	PIM1	S253	R248W	248	Missense	distal	-5	no	0.002	0.001	EPSD;PhosphoSitePlus	COSMIC	0.001	Down-regulation
CAMK_PIM_PIM1_ST	O43524	FOXO3	P11309	PIM1	S280	Q275R	275	Missense	distal	-5	no	0.000	0.001	EPSD	COSMIC	0.001	Gain
CAMK_PIM_PIM1_ST	O43524	FOXO3	P11309	PIM1	T363	T363A	363	Missense	central	0	yes	0.001	0.000	EPSD	COSMIC;GDSC;CCLE	0.001	Loss
CAMK_PIM_PIM1_ST	O43524	FOXO3	P11309	PIM1	S402	P397R	397	Missense	distal	-5	no	0.000	0.001	EPSD	COSMIC	0.001	Gain
CAMK_PIM_PIM1_ST	P29474	NOS3	P11309	PIM1	S615	K610Q	610	Missense	distal	-5	no	0.002	0.001	EPSD	COSMIC	0.001	Down-regulation
CAMK_PIM_PIM1_ST	P29474	NOS3	P11309	PIM1	T785	R782H	782	Missense	distal	-3	no	0.001	0.000	EPSD	COSMIC;CCLE	0.001	Loss
CAMK_PIM_PIM1_ST	Q9Y4H2	IRS2	P11309	PIM1	S14	P9R	9	Missense	distal	-5	no	0.000	0.001	EPSD	COSMIC	0.001	Gain
CAMK_PIM_PIM1_ST	Q9Y4H2	IRS2	P11309	PIM1	S304	R301W	301	Missense	distal	-3	no	0.001	0.000	EPSD	COSMIC	0.001	Loss
CAMK_PIM_PIM1_ST	Q9Y4H2	IRS2	P11309	PIM1	S306	R303H	303	Missense	distal	-3	no	0.002	0.001	EPSD	COSMIC;CCLE	0.001	Down-regulation
CAMK_PIM_PIM1_ST	Q9Y4H2	IRS2	P11309	PIM1	S306	R301W	301	Missense	distal	-5	no	0.002	0.001	EPSD	COSMIC	0.001	Down-regulation
CAMK_PIM_PIM1_ST	Q9Y4H2	IRS2	P11309	PIM1	S308	R303H	303	Missense	distal	-5	no	0.002	0.001	EPSD	COSMIC;CCLE	0.001	Down-regulation
CAMK_PIM_PIM1_ST	Q9Y4H2	IRS2	P11309	PIM1	S308	S308L	308	Missense	central	0	yes	0.002	0.000	EPSD	COSMIC	0.001	Loss
CAMK_PIM_PIM1_ST	Q9Y4H2	IRS2	P11309	PIM1	T344	R341H	341	Missense	distal	-3	no	0.001	0.000	EPSD	COSMIC	0.001	Loss
CAMK_PIM_PIM1_ST	Q9Y4H2	IRS2	P11309	PIM1	S346	R341H	341	Missense	distal	-5	no	0.002	0.001	EPSD	COSMIC	0.001	Down-regulation
CAMK_PIM_PIM1_ST	Q9Y4H2	IRS2	P11309	PIM1	T404	R401P	401	Missense	distal	-3	no	0.001	0.000	EPSD	COSMIC	0.001	Loss
CAMK_PIM_PIM1_ST	Q9Y4H2	IRS2	P11309	PIM1	S406	R401P	401	Missense	distal	-5	no	0.001	0.000	EPSD	COSMIC	0.001	Loss
CAMK_PIM_PIM1_ST	Q9Y4H2	IRS2	P11309	PIM1	S432	S432F	432	Missense	central	0	yes	0.001	0.000	EPSD	COSMIC	0.001	Loss
CAMK_PIM_PIM1_ST	Q9Y4H2	IRS2	P11309	PIM1	S505	E502K	502	Missense	distal	-3	no	0.000	0.001	EPSD	COSMIC	0.001	Gain
CAMK_PIM_PIM1_ST	Q9Y4H2	IRS2	P11309	PIM1	S550	S550N	550	Missense	central	0	yes	0.001	0.000	EPSD	COSMIC	0.001	Loss
CAMK_PIM_PIM1_ST	Q9Y4H2	IRS2	P11309	PIM1	S560	R557C	557	Missense	distal	-3	no	0.001	0.000	EPSD	COSMIC	0.001	Loss
CAMK_PIM_PIM1_ST	Q9Y4H2	IRS2	P11309	PIM1	S577	S577F	577	Missense	central	0	yes	0.003	0.000	EPSD	COSMIC	0.001	Loss
CAMK_PIM_PIM1_ST	Q9Y4H2	IRS2	P11309	PIM1	S644	S644R	644	Missense	central	0	yes	0.001	0.000	EPSD	COSMIC	0.001	Loss
CAMK_PIM_PIM1_ST	Q9Y4H2	IRS2	P11309	PIM1	S731	K728E	728	Missense	distal	-3	no	0.001	0.000	EPSD	COSMIC	0.001	Loss
CAMK_PIM_PIM1_ST	Q9Y4H2	IRS2	P11309	PIM1	S735	S730R	730	Missense	distal	-5	no	0.000	0.001	EPSD	COSMIC	0.001	Gain
CAMK_PIM_PIM1_ST	Q9Y4H2	IRS2	P11309	PIM1	S749	R744H	744	Missense	distal	-5	no	0.001	0.000	EPSD	COSMIC	0.001	Loss
CAMK_PIM_PIM1_ST	Q9Y4H2	IRS2	P11309	PIM1	T891	R884H	884	Missense	distal	-7	no	0.002	0.001	EPSD	COSMIC	0.001	Down-regulation
CAMK_PIM_PIM1_ST	Q9Y4H2	IRS2	P11309	PIM1	T891	R884L	884	Missense	distal	-7	no	0.002	0.001	EPSD	COSMIC	0.001	Down-regulation
CAMK_PIM_PIM1_ST	Q9Y4H2	IRS2	P11309	PIM1	T891	T891P	891	Missense	central	0	yes	0.002	0.000	EPSD	COSMIC	0.001	Loss
CAMK_PIM_PIM1_ST	Q9Y4H2	IRS2	P11309	PIM1	S894	T891P	891	Missense	distal	-3	no	0.002	0.001	EPSD	COSMIC	0.001	Down-regulation
CAMK_PIM_PIM1_ST	Q9Y4H2	IRS2	P11309	PIM1	S894	S894F	894	Missense	central	0	yes	0.002	0.000	EPSD	COSMIC	0.001	Loss
CAMK_PIM_PIM1_ST	Q9Y4H2	IRS2	P11309	PIM1	S1100	R1097L	1097	Missense	distal	-3	no	0.001	0.000	EPSD	COSMIC	0.001	Loss
CAMK_PIM_PIM1_ST	Q9Y4H2	IRS2	P11309	PIM1	S1100	R1097H	1097	Missense	distal	-3	no	0.001	0.000	EPSD	COSMIC;CCLE	0.001	Loss
CAMK_PIM_PIM1_ST	Q9Y4H2	IRS2	P11309	PIM1	T1102	R1097L	1097	Missense	distal	-5	no	0.001	0.000	EPSD	COSMIC	0.001	Loss
CAMK_PIM_PIM1_ST	Q9Y4H2	IRS2	P11309	PIM1	T1102	R1097H	1097	Missense	distal	-5	no	0.001	0.000	EPSD	COSMIC;CCLE	0.001	Loss
CAMK_PIM_PIM1_ST	Q9Y4H2	IRS2	P11309	PIM1	T1102	T1102M	1102	Missense	central	0	yes	0.001	0.000	EPSD	COSMIC	0.001	Loss
CAMK_PIM_PIM1_ST	Q9Y4H2	IRS2	P11309	PIM1	S1109	K1106N	1106	Missense	distal	-3	no	0.001	0.000	EPSD	COSMIC	0.001	Loss
CAMK_PIM_PIM1_ST	Q9Y4H2	IRS2	P11309	PIM1	S1148	R1145L	1145	Missense	distal	-3	no	0.001	0.000	EPSD	COSMIC	0.001	Loss
CAMK_PIM_PIM1_ST	Q9Y4H2	IRS2	P11309	PIM1	S1148	R1145H	1145	Missense	distal	-3	no	0.001	0.000	EPSD	COSMIC	0.001	Loss
CAMK_PIM_PIM1_ST	Q9Y4H2	IRS2	P11309	PIM1	S1149	R1145L	1145	Missense	distal	-4	no	0.003	0.002	PhosphoSitePlus	COSMIC	0.001	Down-regulation
CAMK_PIM_PIM1_ST	Q9Y4H2	IRS2	P11309	PIM1	S1149	R1145H	1145	Missense	distal	-4	no	0.003	0.002	PhosphoSitePlus	COSMIC	0.001	Down-regulation
CAMK_PIM_PIM1_ST	Q9Y4H2	IRS2	P11309	PIM1	S1174	S1174L	1174	Missense	central	0	yes	0.001	0.000	EPSD	COSMIC	0.001	Loss
CAMK_PIM_PIM1_ST	Q9Y4H2	IRS2	P11309	PIM1	S1174	R1171C	1171	Missense	distal	-3	no	0.001	0.000	EPSD	COSMIC	0.001	Loss
CAMK_PIM_PIM1_ST	Q9Y4H2	IRS2	P11309	PIM1	S1176	R1171C	1171	Missense	distal	-5	no	0.001	0.000	EPSD	COSMIC	0.001	Loss
CAMK_PIM_PIM1_ST	Q9Y4H2	IRS2	P11309	PIM1	S1282	Q1277R	1277	Missense	distal	-5	no	0.000	0.001	EPSD	COSMIC	0.001	Gain
CAMK_PIM_PIM1_ST	Q9Y4H2	IRS2	P11309	PIM1	S1289	R1286W	1286	Missense	distal	-3	no	0.001	0.000	EPSD	COSMIC	0.001	Loss
CAMK_PIM_PIM1_ST	Q9Y4H2	IRS2	P11309	PIM1	S1289	R1286L	1286	Missense	distal	-3	no	0.001	0.000	EPSD	COSMIC	0.001	Loss
CAMK_PIM_PIM1_ST	Q9Y4H2	IRS2	P11309	PIM1	S1289	R1286Q	1286	Missense	distal	-3	no	0.001	0.000	EPSD	COSMIC	0.001	Loss
CAMK_PIM_PIM1_ST	P46527	CDKN1B	P11309	PIM1	S10	R5L	5	Missense	distal	-5	no	0.001	0.000	EPSD	COSMIC	0.001	Loss
CAMK_PIM_PIM1_ST	P46527	CDKN1B	P11309	PIM1	S110	Q107R	107	Missense	distal	-3	no	0.000	0.001	EPSD	COSMIC	0.001	Gain
CAMK_PIM_PIM1_ST	P46527	CDKN1B	P11309	PIM1	S112	Q107R	107	Missense	distal	-5	no	0.000	0.001	EPSD	COSMIC	0.001	Gain
CAMK_PIM_PIM1_ST	P46527	CDKN1B	P11309	PIM1	T157	T157N	157	Missense	central	0	yes	0.002	0.000	PhosphoSitePlus;EPSD	COSMIC	0.001	Loss
CAMK_PIM_PIM1_ST	O60381	HBP1	P11309	PIM1	S380	Q376P	376	Missense	distal	-4	no	0.003	0.002	PhosphoSitePlus;EPSD	COSMIC	0.001	Down-regulation
CAMK_PIM_PIM1_ST	O60381	HBP1	P11309	PIM1	S380	R378C	378	Missense	proximal	-2	no	0.003	0.002	PhosphoSitePlus;EPSD	COSMIC	0.001	Down-regulation
CAMK_PIM_PIM1_ST	O60381	HBP1	P11309	PIM1	T484	R481I	481	Missense	distal	-3	no	0.001	0.000	EPSD	COSMIC	0.001	Loss
CAMK_PIM_PIM1_ST	O60381	HBP1	P11309	PIM1	S509	R506G	506	Missense	distal	-3	no	0.002	0.001	EPSD	COSMIC	0.001	Down-regulation
CAMK_PIM_PIM1_ST	Q99801	NKX3-1	P11309	PIM1	S48	R45S	45	Missense	distal	-3	no	0.001	0.000	EPSD	COSMIC	0.001	Loss
CAMK_PIM_PIM1_ST	Q99801	NKX3-1	P11309	PIM1	T89	E86K	86	Missense	distal	-3	no	0.000	0.001	EPSD;PhosphoSitePlus	COSMIC	0.001	Gain
CAMK_PIM_PIM1_ST	Q99801	NKX3-1	P11309	PIM1	S185	K180E	180	Missense	distal	-5	no	0.002	0.001	EPSD;PhosphoSitePlus	COSMIC	0.001	Down-regulation
CAMK_PIM_PIM1_ST	Q9UNQ0	ABCG2	P11309	PIM1	S195	E190K	190	Missense	distal	-5	no	0.001	0.002	EPSD	COSMIC	0.001	Up-regulation
CAMK_PIM_PIM1_ST	Q04206	RELA	P11309	PIM1	S131	R124W	124	Missense	distal	-7	no	0.001	0.000	EPSD	COSMIC	0.001	Loss
CAMK_PIM_PIM1_ST	Q04206	RELA	P11309	PIM1	S281	R278Q	278	Missense	distal	-3	no	0.001	0.000	EPSD	COSMIC	0.001	Loss
CAMK_PIM_PIM1_ST	Q04206	RELA	P11309	PIM1	T305	R302C	302	Missense	distal	-3	no	0.001	0.000	EPSD	COSMIC	0.001	Loss
CAMK_PIM_PIM1_ST	Q04206	RELA	P11309	PIM1	T305	E300K	300	Missense	distal	-5	no	0.001	0.002	EPSD	COSMIC	0.001	Up-regulation
CAMK_PIM_PIM1_ST	Q04206	RELA	P11309	PIM1	T305	T305A	305	Missense	central	0	yes	0.001	0.000	EPSD	COSMIC	0.001	Loss
CAMK_PIM_PIM1_ST	Q04206	RELA	P11309	PIM1	S319	K314N	314	Missense	distal	-5	no	0.001	0.000	EPSD	COSMIC	0.001	Loss
CAMK_PIM_PIM1_ST	Q04206	RELA	P11309	PIM1	S335	R330C	330	Missense	distal	-5	no	0.001	0.000	EPSD	COSMIC	0.001	Loss
CAMK_PIM_PIM1_ST	Q04206	RELA	P11309	PIM1	T505	R502P	502	Missense	distal	-3	no	0.001	0.000	EPSD	COSMIC	0.001	Loss
CAMK_PIM_PIM1_ST	P10275	AR	P11309	PIM1	S16	R13W	13	Missense	distal	-3	no	0.001	0.000	EPSD	COSMIC	0.001	Loss
CAMK_PIM_PIM1_ST	P10275	AR	P11309	PIM1	T18	R13W	13	Missense	distal	-5	no	0.001	0.000	EPSD	COSMIC	0.001	Loss
CAMK_PIM_PIM1_ST	P10275	AR	P11309	PIM1	S215	S215L	215	Missense	central	0	yes	0.002	0.000	EPSD;PhosphoSitePlus	COSMIC	0.001	Loss
CAMK_PIM_PIM1_ST	P10275	AR	P11309	PIM1	S258	E255K	255	Missense	distal	-3	no	0.000	0.001	EPSD	COSMIC	0.001	Gain
CAMK_PIM_PIM1_ST	P10275	AR	P11309	PIM1	T303	S298R	298	Missense	distal	-5	no	0.000	0.001	EPSD	COSMIC	0.001	Gain
CAMK_PIM_PIM1_ST	P10275	AR	P11309	PIM1	S424	G421R	421	Missense	distal	-3	no	0.000	0.001	EPSD	COSMIC	0.001	Gain
CAMK_PIM_PIM1_ST	P10275	AR	P11309	PIM1	S426	G421R	421	Missense	distal	-5	no	0.000	0.001	EPSD	COSMIC	0.001	Gain
CAMK_PIM_PIM1_ST	P10275	AR	P11309	PIM1	S648	E643K	643	Missense	distal	-5	no	0.000	0.001	EPSD	COSMIC	0.001	Gain
CAMK_PIM_PIM1_ST	P10275	AR	P11309	PIM1	S651	S648R	648	Missense	distal	-3	no	0.000	0.001	EPSD	COSMIC	0.001	Gain
CAMK_PIM_PIM1_ST	P10275	AR	P11309	PIM1	T653	S648R	648	Missense	distal	-5	no	0.000	0.001	EPSD	COSMIC	0.001	Gain
CAMK_PIM_PIM1_ST	P10275	AR	P11309	PIM1	T657	E654K	654	Missense	distal	-3	no	0.000	0.001	EPSD	COSMIC	0.001	Gain
CAMK_PIM_PIM1_ST	P10275	AR	P11309	PIM1	S792	S792F	792	Missense	central	0	yes	0.002	0.000	EPSD	COSMIC	0.001	Loss
CAMK_PIM_PIM1_ST	P10275	AR	P11309	PIM1	S792	S792P	792	Missense	central	0	yes	0.002	0.000	EPSD	COSMIC	0.001	Loss
CAMK_PIM_PIM1_ST	P10275	AR	P11309	PIM1	T851	K848N	848	Missense	distal	-3	no	0.002	0.001	PhosphoSitePlus;EPSD	COSMIC	0.001	Down-regulation
CAMK_PIM_PIM1_ST	P10275	AR	P11309	PIM1	T851	R847G	847	Missense	distal	-4	no	0.002	0.001	PhosphoSitePlus;EPSD	COSMIC	0.001	Down-regulation
CAMK_PIM_PIM1_ST	P61073	CXCR4	P11309	PIM1	S5	E2K	2	Missense	distal	-3	no	0.000	0.001	EPSD	COSMIC	0.001	Gain
CAMK_PIM_PIM1_ST	P61073	CXCR4	P11309	PIM1	T8	G3R	3	Missense	distal	-5	no	0.000	0.001	EPSD	COSMIC	0.001	Gain
CAMK_PIM_PIM1_ST	P61073	CXCR4	P11309	PIM1	T311	T311A	311	Missense	central	0	yes	0.001	0.000	EPSD	COSMIC	0.001	Loss
CAMK_PIM_PIM1_ST	P61073	CXCR4	P11309	PIM1	T311	G306R	306	Missense	distal	-5	no	0.001	0.002	EPSD	COSMIC	0.001	Up-regulation
CAMK_PIM_PIM1_ST	P61073	CXCR4	P11309	PIM1	S325	S325R	325	Missense	central	0	yes	0.001	0.000	EPSD	COSMIC	0.001	Loss
CAMK_PIM_PIM1_ST	P61073	CXCR4	P11309	PIM1	S330	S325R	325	Missense	distal	-5	no	0.000	0.002	EPSD	COSMIC	0.001	Gain
CAMK_PIM_PIM1_ST	P61073	CXCR4	P11309	PIM1	S330	G336R	336	Missense	distal	6	no	0.000	0.001	EPSD	COSMIC	0.001	Gain
CAMK_PIM_PIM1_ST	P61073	CXCR4	P11309	PIM1	S330	S324F	324	Missense	distal	-6	no	0.000	0.001	EPSD	COSMIC	0.001	Gain
CAMK_PIM_PIM1_ST	P61073	CXCR4	P11309	PIM1	S338	S338A	338	Missense	central	0	yes	0.001	0.000	EPSD	COSMIC	0.001	Loss
CAMK_PIM_PIM1_ST	P61073	CXCR4	P11309	PIM1	S339	G336R	336	Missense	distal	-3	no	0.001	0.002	PhosphoSitePlus	COSMIC	0.001	Up-regulation
CAMK_PIM_PIM1_ST	P61073	CXCR4	P11309	PIM1	S339	S339F	339	Missense	central	0	yes	0.001	0.000	PhosphoSitePlus	COSMIC	0.001	Loss
CAMK_PIM_PIM1_ST	P61073	CXCR4	P11309	PIM1	S341	G336R	336	Missense	distal	-5	no	0.000	0.001	EPSD	COSMIC	0.001	Gain
CAMK_PIM_PIM1_ST	P61073	CXCR4	P11309	PIM1	S348	E343K	343	Missense	distal	-5	no	0.000	0.001	EPSD	COSMIC	0.001	Gain
CAMK_PIM_PIM1_ST	Q9BZS1	FOXP3	P11309	PIM1	S422	R417W	417	Missense	distal	-5	no	0.002	0.000	PhosphoSitePlus	COSMIC;GDSC;CCLE	0.001	Loss
STE_STE20_MST_STK4_ST	Q14457	BECN1	Q13043	STK4	S7	K5R	5	Missense	proximal	-2	no	4.905	4.895	EPSD	COSMIC	4.850	Down-regulation
STE_STE20_MST_STK4_ST	Q14457	BECN1	Q13043	STK4	S10	K5R	5	Missense	distal	-5	no	4.885	4.814	EPSD	COSMIC	4.850	Loss
STE_STE20_MST_STK4_ST	Q14457	BECN1	Q13043	STK4	T11	K5R	5	Missense	distal	-6	no	4.982	4.962	EPSD	COSMIC	4.850	Down-regulation
STE_STE20_MST_STK4_ST	Q14457	BECN1	Q13043	STK4	S64	E67K	67	Missense	distal	3	no	4.912	4.901	EPSD	COSMIC;GDSC	4.850	Down-regulation
STE_STE20_MST_STK4_ST	Q14457	BECN1	Q13043	STK4	S64	E61G	61	Missense	distal	-3	no	4.912	4.868	EPSD	COSMIC	4.850	Down-regulation
STE_STE20_MST_STK4_ST	Q14457	BECN1	Q13043	STK4	T72	E67K	67	Missense	distal	-5	no	4.913	4.941	EPSD	COSMIC;GDSC	4.850	Up-regulation
STE_STE20_MST_STK4_ST	Q14457	BECN1	Q13043	STK4	T72	Q75L	75	Missense	distal	3	no	4.913	4.902	EPSD	COSMIC	4.850	Down-regulation
STE_STE20_MST_STK4_ST	Q14457	BECN1	Q13043	STK4	S409	E404K	404	Missense	distal	-5	no	4.872	4.900	EPSD	COSMIC	4.850	Up-regulation
STE_STE20_MST_STK4_ST	Q14457	BECN1	Q13043	STK4	T417	T417N	417	Missense	central	0	yes	4.873	0.000	EPSD	COSMIC	4.850	Loss
STE_STE20_MST_STK4_ST	Q06830	PRDX1	Q13043	STK4	T18	A17V	17	Missense	proximal	-1	no	4.889	4.888	EPSD;PhosphoSitePlus	COSMIC	4.850	Down-regulation
STE_STE20_MST_STK4_ST	Q06830	PRDX1	Q13043	STK4	T18	A19P	19	Missense	proximal	1	no	4.889	4.919	EPSD;PhosphoSitePlus	COSMIC	4.850	Up-regulation
STE_STE20_MST_STK4_ST	P19429	TNNI3	Q13043	STK4	S23	S23P	23	Missense	central	0	yes	4.968	0.000	EPSD	COSMIC	4.850	Loss
STE_STE20_MST_STK4_ST	P19429	TNNI3	Q13043	STK4	S77	Q81H	81	Missense	distal	4	no	4.877	4.861	EPSD	COSMIC	4.850	Down-regulation
STE_STE20_MST_STK4_ST	P19429	TNNI3	Q13043	STK4	S77	A75S	75	Missense	proximal	-2	no	4.877	4.868	EPSD	COSMIC	4.850	Down-regulation
STE_STE20_MST_STK4_ST	P19429	TNNI3	Q13043	STK4	S77	P82S	82	Missense	distal	5	no	4.877	4.965	EPSD	COSMIC	4.850	Up-regulation
STE_STE20_MST_STK4_ST	P19429	TNNI3	Q13043	STK4	T143	R141Q	141	Missense	proximal	-2	no	4.934	4.917	EPSD;PhosphoSitePlus	COSMIC	4.850	Down-regulation
STE_STE20_MST_STK4_ST	P19429	TNNI3	Q13043	STK4	T143	R146I	146	Missense	distal	3	no	4.934	4.921	EPSD;PhosphoSitePlus	COSMIC	4.850	Down-regulation
STE_STE20_MST_STK4_ST	Q13043	STK4	Q13043	STK4	S21	D20N	20	Missense	proximal	-1	no	4.871	4.870	EPSD	COSMIC	4.850	Down-regulation
STE_STE20_MST_STK4_ST	Q13043	STK4	Q13043	STK4	T23	D20N	20	Missense	distal	-3	no	4.974	4.977	EPSD	COSMIC	4.850	Up-regulation
STE_STE20_MST_STK4_ST	Q13043	STK4	Q13043	STK4	S307	R310W	310	Missense	distal	3	no	4.846	4.855	EPSD	COSMIC	4.850	Gain
STE_STE20_MST_STK4_ST	Q13043	STK4	Q13043	STK4	S327	E321K	321	Missense	distal	-6	no	4.895	4.890	EPSD	COSMIC	4.850	Down-regulation
STE_STE20_MST_STK4_ST	Q13043	STK4	Q13043	STK4	S422	D424G	424	Missense	proximal	2	no	4.854	4.820	EPSD	COSMIC	4.850	Loss
STE_STE20_MST_STK4_ST	Q13043	STK4	Q13043	STK4	S422	K420E	420	Missense	proximal	-2	no	4.854	4.850	EPSD	COSMIC	4.850	Down-regulation
STE_STE20_MST_STK4_ST	Q13043	STK4	Q13043	STK4	S422	P418Q	418	Missense	distal	-4	no	4.854	4.853	EPSD	COSMIC	4.850	Down-regulation
STE_STE20_MST_STK4_ST	Q13043	STK4	Q13043	STK4	S422	P416L	416	Missense	distal	-6	no	4.854	4.843	EPSD	COSMIC	4.850	Loss
STE_STE20_MST_STK4_ST	Q13043	STK4	Q13043	STK4	T440	R447T	447	Missense	distal	7	no	4.856	4.851	EPSD	COSMIC	4.850	Down-regulation
STE_STE20_MST_STK4_ST	P00519	ABL1	Q13043	STK4	S50	R47G	47	Missense	distal	-3	no	4.893	4.851	EPSD	COSMIC	4.850	Down-regulation
STE_STE20_MST_STK4_ST	P00519	ABL1	Q13043	STK4	S50	G57E	57	Missense	distal	7	no	4.893	4.873	EPSD	COSMIC	4.850	Down-regulation
STE_STE20_MST_STK4_ST	P00519	ABL1	Q13043	STK4	S50	A56V	56	Missense	distal	6	no	4.893	4.887	EPSD	COSMIC	4.850	Down-regulation
STE_STE20_MST_STK4_ST	P00519	ABL1	Q13043	STK4	S154	P158L	158	Missense	distal	4	no	4.904	4.885	EPSD	COSMIC	4.850	Down-regulation
STE_STE20_MST_STK4_ST	P00519	ABL1	Q13043	STK4	S154	E155K	155	Missense	proximal	1	no	4.904	4.910	EPSD	COSMIC	4.850	Up-regulation
STE_STE20_MST_STK4_ST	P00519	ABL1	Q13043	STK4	S154	S156N	156	Missense	proximal	2	no	4.904	4.925	EPSD	COSMIC	4.850	Up-regulation
STE_STE20_MST_STK4_ST	P00519	ABL1	Q13043	STK4	S157	P158L	158	Missense	proximal	1	no	4.874	4.878	EPSD	COSMIC	4.850	Up-regulation
STE_STE20_MST_STK4_ST	P00519	ABL1	Q13043	STK4	S157	E155K	155	Missense	proximal	-2	no	4.874	4.879	EPSD	COSMIC	4.850	Up-regulation
STE_STE20_MST_STK4_ST	P00519	ABL1	Q13043	STK4	S157	S162F	162	Missense	distal	5	no	4.874	4.784	EPSD	COSMIC	4.850	Loss
STE_STE20_MST_STK4_ST	P00519	ABL1	Q13043	STK4	S187	R191C	191	Missense	distal	4	no	4.875	4.872	EPSD	COSMIC	4.850	Down-regulation
STE_STE20_MST_STK4_ST	P00519	ABL1	Q13043	STK4	S187	T194I	194	Missense	distal	7	no	4.875	4.874	EPSD	COSMIC	4.850	Down-regulation
STE_STE20_MST_STK4_ST	P00519	ABL1	Q13043	STK4	S187	S187F	187	Missense	central	0	yes	4.875	0.000	EPSD	COSMIC	4.850	Loss
STE_STE20_MST_STK4_ST	P00519	ABL1	Q13043	STK4	S187	L184R	184	Missense	distal	-3	no	4.875	4.909	EPSD	COSMIC	4.850	Up-regulation
STE_STE20_MST_STK4_ST	P00519	ABL1	Q13043	STK4	T224	N231S	231	Missense	distal	7	no	4.848	4.863	EPSD	COSMIC	4.850	Gain
STE_STE20_MST_STK4_ST	P00519	ABL1	Q13043	STK4	T243	G250E	250	Missense	distal	7	no	4.925	4.905	EPSD	COSMIC	4.850	Down-regulation
STE_STE20_MST_STK4_ST	P00519	ABL1	Q13043	STK4	T243	M244V	244	Missense	proximal	1	no	4.925	4.892	EPSD	COSMIC	4.850	Down-regulation
STE_STE20_MST_STK4_ST	P00519	ABL1	Q13043	STK4	T243	L248V	248	Missense	distal	5	no	4.925	4.945	EPSD	COSMIC	4.850	Up-regulation
STE_STE20_MST_STK4_ST	P00519	ABL1	Q13043	STK4	T243	K247E	247	Missense	distal	4	no	4.925	4.938	EPSD	COSMIC	4.850	Up-regulation
STE_STE20_MST_STK4_ST	P00519	ABL1	Q13043	STK4	T243	T243I	243	Missense	central	0	yes	4.925	0.000	EPSD	COSMIC;GDSC	4.850	Loss
STE_STE20_MST_STK4_ST	P00519	ABL1	Q13043	STK4	T243	K247R	247	Missense	distal	4	no	4.925	4.946	EPSD	COSMIC	4.850	Up-regulation
STE_STE20_MST_STK4_ST	P00519	ABL1	Q13043	STK4	T243	I242M	242	Missense	proximal	-1	no	4.925	4.921	EPSD	COSMIC	4.850	Down-regulation
STE_STE20_MST_STK4_ST	P00519	ABL1	Q13043	STK4	T243	M237I	237	Missense	distal	-6	no	4.925	4.932	EPSD	COSMIC	4.850	Up-regulation
STE_STE20_MST_STK4_ST	P00519	ABL1	Q13043	STK4	T243	H246D	246	Missense	distal	3	no	4.925	4.924	EPSD	COSMIC	4.850	Down-regulation
STE_STE20_MST_STK4_ST	P00519	ABL1	Q13043	STK4	T243	E238K	238	Missense	distal	-5	no	4.925	4.953	EPSD	COSMIC	4.850	Up-regulation
STE_STE20_MST_STK4_ST	P00519	ABL1	Q13043	STK4	T243	H246R	246	Missense	distal	3	no	4.925	4.920	EPSD	COSMIC	4.850	Down-regulation
STE_STE20_MST_STK4_ST	P00519	ABL1	Q13043	STK4	T243	L248R	248	Missense	distal	5	no	4.925	4.941	EPSD	COSMIC	4.850	Up-regulation
STE_STE20_MST_STK4_ST	P00519	ABL1	Q13043	STK4	S265	K263N	263	Missense	proximal	-2	no	4.897	4.876	EPSD	COSMIC	4.850	Down-regulation
STE_STE20_MST_STK4_ST	P00519	ABL1	Q13043	STK4	S265	S265R	265	Missense	central	0	yes	4.897	0.000	EPSD	COSMIC	4.850	Loss
STE_STE20_MST_STK4_ST	P00519	ABL1	Q13043	STK4	S265	Y264C	264	Missense	proximal	-1	no	4.897	4.900	EPSD	COSMIC	4.850	Up-regulation
STE_STE20_MST_STK4_ST	P00519	ABL1	Q13043	STK4	S265	V270M	270	Missense	distal	5	no	4.897	4.896	EPSD	COSMIC	4.850	Down-regulation
STE_STE20_MST_STK4_ST	P00519	ABL1	Q13043	STK4	S265	S265N	265	Missense	central	0	yes	4.897	0.000	EPSD	COSMIC;CCLE	4.850	Loss
STE_STE20_MST_STK4_ST	P00519	ABL1	Q13043	STK4	S265	V268L	268	Missense	distal	3	no	4.897	4.913	EPSD	COSMIC	4.850	Up-regulation
STE_STE20_MST_STK4_ST	P00519	ABL1	Q13043	STK4	S265	T267A	267	Missense	proximal	2	no	4.897	4.868	EPSD	COSMIC	4.850	Down-regulation
STE_STE20_MST_STK4_ST	P00519	ABL1	Q13043	STK4	S265	E258A	258	Missense	distal	-7	no	4.897	4.899	EPSD	COSMIC	4.850	Up-regulation
STE_STE20_MST_STK4_ST	P00519	ABL1	Q13043	STK4	S265	E258V	258	Missense	distal	-7	no	4.897	4.898	EPSD	COSMIC	4.850	Up-regulation
STE_STE20_MST_STK4_ST	P00519	ABL1	Q13043	STK4	S265	Y264N	264	Missense	proximal	-1	no	4.897	4.900	EPSD	COSMIC	4.850	Up-regulation
STE_STE20_MST_STK4_ST	P00519	ABL1	Q13043	STK4	S265	V268A	268	Missense	distal	3	no	4.897	4.916	EPSD	COSMIC	4.850	Up-regulation
STE_STE20_MST_STK4_ST	P00519	ABL1	Q13043	STK4	S265	V260A	260	Missense	distal	-5	no	4.897	4.875	EPSD	COSMIC	4.850	Down-regulation
STE_STE20_MST_STK4_ST	P00519	ABL1	Q13043	STK4	T389	T394A	394	Missense	distal	5	no	4.782	4.859	EPSD	COSMIC	4.850	Gain
STE_STE20_MST_STK4_ST	P00519	ABL1	Q13043	STK4	T394	H396R	396	Missense	proximal	2	no	4.819	4.854	EPSD	COSMIC	4.850	Gain
STE_STE20_MST_STK4_ST	P00519	ABL1	Q13043	STK4	S620	G626D	626	Missense	distal	6	no	4.842	4.853	EPSD	COSMIC	4.850	Gain
STE_STE20_MST_STK4_ST	P00519	ABL1	Q13043	STK4	S620	G626S	626	Missense	distal	6	no	4.842	4.852	EPSD	COSMIC	4.850	Gain
STE_STE20_MST_STK4_ST	P00519	ABL1	Q13043	STK4	S804	V797I	797	Missense	distal	-7	no	4.867	4.868	EPSD	COSMIC	4.850	Up-regulation
STE_STE20_MST_STK4_ST	P00519	ABL1	Q13043	STK4	S804	G807S	807	Missense	distal	3	no	4.867	4.865	EPSD	COSMIC	4.850	Down-regulation
STE_STE20_MST_STK4_ST	P00519	ABL1	Q13043	STK4	S804	P806L	806	Missense	proximal	2	no	4.867	4.865	EPSD	COSMIC	4.850	Down-regulation
STE_STE20_MST_STK4_ST	P00519	ABL1	Q13043	STK4	T854	G858S	858	Missense	distal	4	no	4.839	4.859	EPSD	COSMIC	4.850	Gain
STE_STE20_MST_STK4_ST	P00519	ABL1	Q13043	STK4	S855	G858S	858	Missense	distal	3	no	4.892	4.890	EPSD	COSMIC	4.850	Down-regulation
STE_STE20_MST_STK4_ST	P00519	ABL1	Q13043	STK4	S855	P850L	850	Missense	distal	-5	no	4.892	4.897	EPSD	COSMIC	4.850	Up-regulation
STE_STE20_MST_STK4_ST	P00519	ABL1	Q13043	STK4	S855	P850S	850	Missense	distal	-5	no	4.892	4.873	EPSD	COSMIC	4.850	Down-regulation
STE_STE20_MST_STK4_ST	P00519	ABL1	Q13043	STK4	S855	G860C	860	Missense	distal	5	no	4.892	4.888	EPSD	COSMIC	4.850	Down-regulation
STE_STE20_MST_STK4_ST	P00519	ABL1	Q13043	STK4	S855	A861T	861	Missense	distal	6	no	4.892	4.894	EPSD	COSMIC	4.850	Up-regulation
STE_STE20_MST_STK4_ST	P00519	ABL1	Q13043	STK4	S859	G858S	858	Missense	proximal	-1	no	4.920	4.917	EPSD	COSMIC	4.850	Down-regulation
STE_STE20_MST_STK4_ST	P00519	ABL1	Q13043	STK4	S859	G860C	860	Missense	proximal	1	no	4.920	4.883	EPSD	COSMIC	4.850	Down-regulation
STE_STE20_MST_STK4_ST	P00519	ABL1	Q13043	STK4	S859	G864S	864	Missense	distal	5	no	4.920	5.003	EPSD	COSMIC	4.850	Up-regulation
STE_STE20_MST_STK4_ST	P00519	ABL1	Q13043	STK4	S859	A861T	861	Missense	proximal	2	no	4.920	4.949	EPSD	COSMIC	4.850	Up-regulation
STE_STE20_MST_STK4_ST	P00519	ABL1	Q13043	STK4	S859	G863R	863	Missense	distal	4	no	4.920	4.914	EPSD	COSMIC	4.850	Down-regulation
STE_STE20_MST_STK4_ST	P00519	ABL1	Q13043	STK4	S977	P982S	982	Missense	distal	5	no	4.777	4.865	EPSD	COSMIC	4.850	Gain
STE_STE20_MST_STK4_ST	O43524	FOXO3	Q13043	STK4	S7	A2V	2	Missense	distal	-5	no	4.845	4.868	EPSD	COSMIC;CCLE	4.850	Gain
STE_STE20_MST_STK4_ST	O43524	FOXO3	Q13043	STK4	S12	A6S	6	Missense	distal	-6	no	4.959	4.957	EPSD	COSMIC	4.850	Down-regulation
STE_STE20_MST_STK4_ST	O43524	FOXO3	Q13043	STK4	S200	S203F	203	Missense	distal	3	no	4.885	4.878	EPSD	COSMIC	4.850	Down-regulation
STE_STE20_MST_STK4_ST	O43524	FOXO3	Q13043	STK4	S200	F194Y	194	Missense	distal	-6	no	4.885	4.892	EPSD	COSMIC	4.850	Up-regulation
STE_STE20_MST_STK4_ST	O43524	FOXO3	Q13043	STK4	S209	L216Q	216	Missense	distal	7	no	5.012	5.019	EPSD;PhosphoSitePlus	COSMIC	4.850	Up-regulation
STE_STE20_MST_STK4_ST	O43524	FOXO3	Q13043	STK4	S209	I210S	210	Missense	proximal	1	no	5.012	4.993	EPSD;PhosphoSitePlus	COSMIC	4.850	Down-regulation
STE_STE20_MST_STK4_ST	O43524	FOXO3	Q13043	STK4	S209	S203F	203	Missense	distal	-6	no	5.012	5.013	EPSD;PhosphoSitePlus	COSMIC	4.850	Up-regulation
STE_STE20_MST_STK4_ST	O43524	FOXO3	Q13043	STK4	S215	L216Q	216	Missense	proximal	1	no	4.998	4.996	EPSD;PhosphoSitePlus	COSMIC	4.850	Down-regulation
STE_STE20_MST_STK4_ST	O43524	FOXO3	Q13043	STK4	S215	I210S	210	Missense	distal	-5	no	4.998	4.962	EPSD;PhosphoSitePlus	COSMIC	4.850	Down-regulation
STE_STE20_MST_STK4_ST	O43524	FOXO3	Q13043	STK4	T228	Q224H	224	Missense	distal	-4	no	4.912	4.911	EPSD	COSMIC	4.850	Down-regulation
STE_STE20_MST_STK4_ST	O43524	FOXO3	Q13043	STK4	T228	G229C	229	Missense	proximal	1	no	4.912	4.874	EPSD	COSMIC	4.850	Down-regulation
STE_STE20_MST_STK4_ST	O43524	FOXO3	Q13043	STK4	S231	G229C	229	Missense	proximal	-2	no	5.023	5.036	PhosphoSitePlus;EPSD	COSMIC	4.850	Up-regulation
STE_STE20_MST_STK4_ST	O43524	FOXO3	Q13043	STK4	S232	G229C	229	Missense	distal	-3	no	4.988	5.006	EPSD;PhosphoSitePlus	COSMIC	4.850	Up-regulation
STE_STE20_MST_STK4_ST	O43524	FOXO3	Q13043	STK4	S243	G240W	240	Missense	distal	-3	no	5.018	5.036	EPSD;PhosphoSitePlus	COSMIC	4.850	Up-regulation
STE_STE20_MST_STK4_ST	O43524	FOXO3	Q13043	STK4	S243	R248W	248	Missense	distal	5	no	5.018	5.016	EPSD;PhosphoSitePlus	COSMIC	4.850	Down-regulation
STE_STE20_MST_STK4_ST	O43524	FOXO3	Q13043	STK4	S344	A341T	341	Missense	distal	-3	no	4.852	4.871	EPSD	COSMIC	4.850	Up-regulation
STE_STE20_MST_STK4_ST	O43524	FOXO3	Q13043	STK4	T395	P397R	397	Missense	proximal	2	no	4.928	4.994	EPSD	COSMIC	4.850	Up-regulation
STE_STE20_MST_STK4_ST	O43524	FOXO3	Q13043	STK4	S421	G424V	424	Missense	distal	3	no	4.896	4.876	EPSD	COSMIC	4.850	Down-regulation
STE_STE20_MST_STK4_ST	O43524	FOXO3	Q13043	STK4	S421	F414Y	414	Missense	distal	-7	no	4.896	4.899	EPSD	COSMIC	4.850	Up-regulation
STE_STE20_MST_STK4_ST	O43524	FOXO3	Q13043	STK4	S429	G424V	424	Missense	distal	-5	no	4.812	4.867	EPSD	COSMIC	4.850	Gain
STE_STE20_MST_STK4_ST	Q14653	IRF3	Q13043	STK4	S259	R262G	262	Missense	distal	3	no	4.918	4.919	EPSD	COSMIC;GDSC;CCLE	4.850	Up-regulation
STE_STE20_MST_STK4_ST	Q14653	IRF3	Q13043	STK4	S259	V261E	261	Missense	proximal	2	no	4.918	4.967	EPSD	COSMIC	4.850	Up-regulation
STE_STE20_MST_STK4_ST	Q96GD4	AURKB	Q13043	STK4	S7	G13V	13	Missense	distal	6	no	4.893	4.903	EPSD	COSMIC	4.850	Up-regulation
STE_STE20_MST_STK4_ST	Q7L9L4	MOB1B	Q13043	STK4	S2	R8H	8	Missense	distal	6	no	5.030	5.022	EPSD	COSMIC;CCLE	4.850	Down-regulation
STE_STE20_MST_STK4_ST	Q7L9L4	MOB1B	Q13043	STK4	S2	L4F	4	Missense	proximal	2	no	5.030	5.044	EPSD	COSMIC	4.850	Up-regulation
STE_STE20_MST_STK4_ST	Q7L9L4	MOB1B	Q13043	STK4	S10	R8H	8	Missense	proximal	-2	no	4.957	4.947	EPSD	COSMIC;CCLE	4.850	Down-regulation
STE_STE20_MST_STK4_ST	Q7L9L4	MOB1B	Q13043	STK4	S10	K11T	11	Missense	proximal	1	no	4.957	4.974	EPSD	COSMIC	4.850	Up-regulation
STE_STE20_MST_STK4_ST	Q7L9L4	MOB1B	Q13043	STK4	S10	L4F	4	Missense	distal	-6	no	4.957	4.941	EPSD	COSMIC	4.850	Down-regulation
STE_STE20_MST_STK4_ST	Q7L9L4	MOB1B	Q13043	STK4	T12	K11T	11	Missense	proximal	-1	no	4.944	4.948	EPSD;PhosphoSitePlus	COSMIC	4.850	Up-regulation
STE_STE20_MST_STK4_ST	Q7L9L4	MOB1B	Q13043	STK4	S23	H24Y	24	Missense	proximal	1	no	4.851	4.877	EPSD	COSMIC	4.850	Up-regulation
STE_STE20_MST_STK4_ST	Q7L9L4	MOB1B	Q13043	STK4	S23	G22D	22	Missense	proximal	-1	no	4.851	4.848	EPSD	COSMIC	4.850	Loss
STE_STE20_MST_STK4_ST	Q7L9L4	MOB1B	Q13043	STK4	S23	G22S	22	Missense	proximal	-1	no	4.851	4.848	EPSD	COSMIC	4.850	Loss
STE_STE20_MST_STK4_ST	Q7L9L4	MOB1B	Q13043	STK4	S38	R42W	42	Missense	distal	4	no	4.923	4.935	EPSD	COSMIC	4.850	Up-regulation
STE_STE20_MST_STK4_ST	Q7L9L4	MOB1B	Q13043	STK4	S38	R42Q	42	Missense	distal	4	no	4.923	4.939	EPSD	COSMIC	4.850	Up-regulation
STE_STE20_MST_STK4_ST	Q7L9L4	MOB1B	Q13043	STK4	S38	V45A	45	Missense	distal	7	no	4.923	4.935	EPSD	COSMIC	4.850	Up-regulation
STE_STE20_MST_STK4_ST	Q7L9L4	MOB1B	Q13043	STK4	S38	A32T	32	Missense	distal	-6	no	4.923	4.934	EPSD	COSMIC;GDSC;CCLE	4.850	Up-regulation
STE_STE20_MST_STK4_ST	P17301	ITGA2	Q13043	STK4	S1036	R1043W	1043	Missense	distal	7	no	4.901	4.907	EPSD	COSMIC	4.850	Up-regulation
STE_STE20_MST_STK4_ST	Q15208	STK38	Q13043	STK4	T4	S6P	6	Missense	proximal	2	no	4.997	5.003	EPSD	COSMIC	4.850	Up-regulation
STE_STE20_MST_STK4_ST	Q15208	STK38	Q13043	STK4	T4	P8S	8	Missense	distal	4	no	4.997	5.030	EPSD	COSMIC	4.850	Up-regulation
STE_STE20_MST_STK4_ST	Q15208	STK38	Q13043	STK4	S6	S6P	6	Missense	central	0	yes	4.955	0.000	EPSD	COSMIC	4.850	Loss
STE_STE20_MST_STK4_ST	Q15208	STK38	Q13043	STK4	S6	P8S	8	Missense	proximal	2	no	4.955	4.949	EPSD	COSMIC	4.850	Down-regulation
STE_STE20_MST_STK4_ST	Q15208	STK38	Q13043	STK4	T7	S6P	6	Missense	proximal	-1	no	4.959	4.958	EPSD	COSMIC	4.850	Down-regulation
STE_STE20_MST_STK4_ST	Q15208	STK38	Q13043	STK4	T7	P8S	8	Missense	proximal	1	no	4.959	4.931	EPSD	COSMIC	4.850	Down-regulation
STE_STE20_MST_STK4_ST	Q15208	STK38	Q13043	STK4	T21	E18K	18	Missense	distal	-3	no	4.934	4.942	EPSD	COSMIC;GDSC	4.850	Up-regulation
STE_STE20_MST_STK4_ST	Q15208	STK38	Q13043	STK4	T21	V20G	20	Missense	proximal	-1	no	4.934	4.938	EPSD	COSMIC	4.850	Up-regulation
STE_STE20_MST_STK4_ST	Q15208	STK38	Q13043	STK4	T23	E18K	18	Missense	distal	-5	no	4.892	4.921	EPSD	COSMIC;GDSC	4.850	Up-regulation
STE_STE20_MST_STK4_ST	Q15208	STK38	Q13043	STK4	T23	V20G	20	Missense	distal	-3	no	4.892	4.875	EPSD	COSMIC	4.850	Down-regulation
STE_STE20_MST_STK4_ST	Q15208	STK38	Q13043	STK4	T26	N33D	33	Missense	distal	7	no	4.858	4.874	EPSD	COSMIC	4.850	Up-regulation
STE_STE20_MST_STK4_ST	Q15208	STK38	Q13043	STK4	T26	V20G	20	Missense	distal	-6	no	4.858	4.848	EPSD	COSMIC	4.850	Loss
STE_STE20_MST_STK4_ST	Q15208	STK38	Q13043	STK4	S252	F257V	257	Missense	distal	5	no	4.928	4.936	EPSD	COSMIC	4.850	Up-regulation
STE_STE20_MST_STK4_ST	Q15208	STK38	Q13043	STK4	S252	P254H	254	Missense	proximal	2	no	4.928	4.958	EPSD	COSMIC	4.850	Up-regulation
STE_STE20_MST_STK4_ST	Q15208	STK38	Q13043	STK4	S252	S255G	255	Missense	distal	3	no	4.928	4.930	EPSD	COSMIC	4.850	Up-regulation
Other_MOS_MOS_ST	P08670	VIM	P00540	MOS	S29	R36H	36	Missense	distal	7	no	2.419	2.362	EPSD	COSMIC	2.415	Loss
Other_MOS_MOS_ST	P08670	VIM	P00540	MOS	S29	S27R	27	Missense	proximal	-2	no	2.419	2.448	EPSD	COSMIC	2.415	Up-regulation
Other_MOS_MOS_ST	P08670	VIM	P00540	MOS	S29	S34P	34	Missense	distal	5	no	2.419	2.475	EPSD	COSMIC	2.415	Up-regulation
Other_MOS_MOS_ST	P08670	VIM	P00540	MOS	T458	Q453E	453	Missense	distal	-5	no	2.469	2.563	EPSD;PhosphoSitePlus	COSMIC;GDSC;CCLE	2.415	Up-regulation
Other_MOS_MOS_ST	P08670	VIM	P00540	MOS	T458	I455V	455	Missense	distal	-3	no	2.469	2.502	EPSD;PhosphoSitePlus	COSMIC	2.415	Up-regulation
Other_MOS_MOS_ST	P08670	VIM	P00540	MOS	S459	Q453E	453	Missense	distal	-6	no	2.783	2.793	PhosphoSitePlus;EPSD	COSMIC;GDSC;CCLE	2.415	Up-regulation
Other_MOS_MOS_ST	P08670	VIM	P00540	MOS	S459	I455V	455	Missense	distal	-4	no	2.783	2.790	PhosphoSitePlus;EPSD	COSMIC	2.415	Up-regulation
STE_STE20_KHS_MAP4K3_ST	Q04759	PRKCQ	Q8IVH8	MAP4K3	S297	C303Y	303	Missense	distal	6	no	3.094	3.184	EPSD	COSMIC;GDSC;CCLE	2.839	Up-regulation
STE_STE20_KHS_MAP4K3_ST	Q04759	PRKCQ	Q8IVH8	MAP4K3	S297	E296G	296	Missense	proximal	-1	no	3.094	3.082	EPSD	COSMIC;GDSC;CCLE	2.839	Down-regulation
STE_STE20_KHS_MAP4K3_ST	Q04759	PRKCQ	Q8IVH8	MAP4K3	T538	L531I	531	Missense	distal	-7	no	8.554	8.524	PhosphoSitePlus	COSMIC	2.839	Down-regulation
STE_STE20_KHS_MAP4K3_ST	Q04759	PRKCQ	Q8IVH8	MAP4K3	T538	D533G	533	Missense	distal	-5	no	8.554	8.374	PhosphoSitePlus	COSMIC	2.839	Down-regulation
STE_STE20_KHS_MAP4K3_ST	Q04759	PRKCQ	Q8IVH8	MAP4K3	T538	D533H	533	Missense	distal	-5	no	8.554	8.342	PhosphoSitePlus	COSMIC	2.839	Down-regulation
STE_STE20_KHS_MAP4K3_ST	Q04759	PRKCQ	Q8IVH8	MAP4K3	T538	Y545C	545	Missense	distal	7	no	8.554	8.490	PhosphoSitePlus	COSMIC	2.839	Down-regulation
STE_STE20_KHS_MAP4K3_ST	Q04759	PRKCQ	Q8IVH8	MAP4K3	T538	G541R	541	Missense	distal	3	no	8.554	5.738	PhosphoSitePlus	COSMIC	2.839	Down-regulation
STE_STE20_KHS_MAP4K3_ST	Q04759	PRKCQ	Q8IVH8	MAP4K3	T538	T536M	536	Missense	proximal	-2	no	8.554	8.581	PhosphoSitePlus	COSMIC	2.839	Up-regulation
STE_STE20_KHS_MAP4K3_ST	P19484	TFEB	Q8IVH8	MAP4K3	S133	A127V	127	Missense	distal	-6	no	2.928	2.855	EPSD	COSMIC	2.839	Down-regulation
STE_STE20_KHS_MAP4K3_ST	P19484	TFEB	Q8IVH8	MAP4K3	S133	N137H	137	Missense	distal	4	no	2.928	2.921	EPSD	COSMIC	2.839	Down-regulation
STE_STE20_KHS_MAP4K3_ST	P19484	TFEB	Q8IVH8	MAP4K3	S133	S134F	134	Missense	proximal	1	no	2.928	2.957	EPSD	COSMIC	2.839	Up-regulation
STE_STE20_KHS_MAP4K3_ST	P19484	TFEB	Q8IVH8	MAP4K3	S133	A135D	135	Missense	proximal	2	no	2.928	2.849	EPSD	COSMIC	2.839	Down-regulation
STE_STE20_KHS_MAP4K3_ST	P19484	TFEB	Q8IVH8	MAP4K3	S332	N337K	337	Missense	distal	5	no	3.655	3.652	EPSD	COSMIC	2.839	Down-regulation
STE_STE20_KHS_MAP4K3_ST	P19484	TFEB	Q8IVH8	MAP4K3	S332	N337D	337	Missense	distal	5	no	3.655	3.649	EPSD	COSMIC	2.839	Down-regulation
STE_STE20_KHS_MAP4K3_ST	P19484	TFEB	Q8IVH8	MAP4K3	S332	P333L	333	Missense	proximal	1	no	3.655	3.649	EPSD	COSMIC	2.839	Down-regulation
STE_STE20_KHS_MAP4K3_ST	P19484	TFEB	Q8IVH8	MAP4K3	S332	P329S	329	Missense	distal	-3	no	3.655	3.653	EPSD	COSMIC	2.839	Down-regulation
STE_STE20_KHS_MAP4K3_ST	Q8IVH8	MAP4K3	Q8IVH8	MAP4K3	S170	S170F	170	Missense	central	0	yes	10.328	0.000	PhosphoSitePlus	COSMIC	2.839	Loss
STE_STE20_KHS_MAP4K3_ST	Q8IVH8	MAP4K3	Q8IVH8	MAP4K3	S295	N290I	290	Missense	distal	-5	no	3.145	3.081	EPSD	COSMIC	2.839	Down-regulation
STE_STE20_KHS_MAP4K3_ST	Q8IVH8	MAP4K3	Q8IVH8	MAP4K3	S295	V289G	289	Missense	distal	-6	no	3.145	2.786	EPSD	COSMIC	2.839	Loss
PKL_FJ_FAM20C_ST	Q9GZV9	FGF23	Q8IXL6	FAM20C	S180	D184N	184	Missense	distal	4	no	6.631	6.626	PhosphoSitePlus	COSMIC	2.180	Down-regulation
PKL_FJ_FAM20C_ST	Q9GZV9	FGF23	Q8IXL6	FAM20C	S180	R179W	179	Missense	proximal	-1	no	6.631	6.472	PhosphoSitePlus	COSMIC	2.180	Down-regulation
PKL_FJ_FAM20C_ST	P23327	HRC	Q8IXL6	FAM20C	S96	V95I	95	Missense	proximal	-1	no	6.169	5.973	PhosphoSitePlus	COSMIC	2.180	Down-regulation
PKL_FJ_FAM20C_ST	P23327	HRC	Q8IXL6	FAM20C	S96	E98K	98	Missense	proximal	2	no	6.169	6.107	PhosphoSitePlus	COSMIC	2.180	Down-regulation
PKL_FJ_FAM20C_ST	P23327	HRC	Q8IXL6	FAM20C	S96	H101R	101	Missense	distal	5	no	6.169	6.151	PhosphoSitePlus	COSMIC	2.180	Down-regulation
PKL_FJ_FAM20C_ST	P23327	HRC	Q8IXL6	FAM20C	S263	D261V	261	Missense	proximal	-2	no	2.405	2.509	EPSD	COSMIC	2.180	Up-regulation
PKL_FJ_FAM20C_ST	P23327	HRC	Q8IXL6	FAM20C	S263	D259H	259	Missense	distal	-4	no	2.405	2.388	EPSD	COSMIC	2.180	Down-regulation
PKL_FJ_FAM20C_ST	P23327	HRC	Q8IXL6	FAM20C	S263	A270T	270	Missense	distal	7	no	2.405	2.392	EPSD	COSMIC	2.180	Down-regulation
PKL_FJ_FAM20C_ST	P23327	HRC	Q8IXL6	FAM20C	S263	V262I	262	Missense	proximal	-1	no	2.405	2.210	EPSD	COSMIC	2.180	Down-regulation
PKL_FJ_FAM20C_ST	P23327	HRC	Q8IXL6	FAM20C	S501	G505R	505	Missense	distal	4	no	2.419	2.482	EPSD	COSMIC	2.180	Up-regulation
PKL_FJ_FAM20C_ST	P23327	HRC	Q8IXL6	FAM20C	S501	G508S	508	Missense	distal	7	no	2.419	2.272	EPSD	COSMIC	2.180	Down-regulation
PKL_FJ_FAM20C_ST	Q96HE7	ERO1A	Q8IXL6	FAM20C	S71	K67T	67	Missense	distal	-4	no	2.255	2.178	EPSD	COSMIC	2.180	Loss
PKL_FJ_FAM20C_ST	Q96HE7	ERO1A	Q8IXL6	FAM20C	S71	S71N	71	Missense	central	0	yes	2.255	0.000	EPSD	COSMIC	2.180	Loss
PKL_FJ_FAM20C_ST	Q96HE7	ERO1A	Q8IXL6	FAM20C	S71	K78T	78	Missense	distal	7	no	2.255	2.159	EPSD	COSMIC	2.180	Loss
PKL_FJ_FAM20C_ST	Q96HE7	ERO1A	Q8IXL6	FAM20C	S71	K78N	78	Missense	distal	7	no	2.255	2.197	EPSD	COSMIC	2.180	Down-regulation
PKL_FJ_FAM20C_ST	Q96HE7	ERO1A	Q8IXL6	FAM20C	S71	R64I	64	Missense	distal	-7	no	2.255	2.340	EPSD	COSMIC	2.180	Up-regulation
PKL_FJ_FAM20C_ST	Q96HE7	ERO1A	Q8IXL6	FAM20C	S71	Y76C	76	Missense	distal	5	no	2.255	2.223	EPSD	COSMIC	2.180	Down-regulation
TK_Eph_EPHA4_Y	P54764	EPHA4	P54764	EPHA4	Y596	G592C	592	Missense	distal	-4	no	4.449	4.453	EPSD;PhosphoSitePlus	COSMIC;GDSC	1.226	Up-regulation
TK_Eph_EPHA4_Y	P54764	EPHA4	P54764	EPHA4	Y596	T601M	601	Missense	distal	5	no	4.449	4.549	EPSD;PhosphoSitePlus	COSMIC;CCLE	1.226	Up-regulation
TK_Eph_EPHA4_Y	P54764	EPHA4	P54764	EPHA4	Y602	D604Y	604	Missense	proximal	2	no	4.080	2.947	PhosphoSitePlus;EPSD	COSMIC	1.226	Down-regulation
TK_Eph_EPHA4_Y	P54764	EPHA4	P54764	EPHA4	Y602	T601M	601	Missense	proximal	-1	no	4.080	3.546	PhosphoSitePlus;EPSD	COSMIC;CCLE	1.226	Down-regulation
TK_Eph_EPHA4_Y	P54764	EPHA4	P54764	EPHA4	Y779	P775S	775	Missense	distal	-4	no	4.985	4.923	EPSD	COSMIC	1.226	Down-regulation
TK_Eph_EPHA4_Y	P54764	EPHA4	P54764	EPHA4	Y779	I786M	786	Missense	distal	7	no	4.985	4.974	EPSD	COSMIC	1.226	Down-regulation
CMGC_MAPK_ERK3_MAPK6_ST	Q9Y6Q9	NCOA3	Q16659	MAPK6	S32	S32N	32	Missense	central	0	yes	2.473	0.000	EPSD	COSMIC	2.026	Loss
CMGC_MAPK_ERK3_MAPK6_ST	Q9Y6Q9	NCOA3	Q16659	MAPK6	S32	R38W	38	Missense	distal	6	no	2.473	2.475	EPSD	COSMIC	2.026	Up-regulation
CMGC_MAPK_ERK3_MAPK6_ST	Q9Y6Q9	NCOA3	Q16659	MAPK6	S543	K547T	547	Missense	distal	4	no	2.188	3.356	EPSD	COSMIC	2.026	Up-regulation
CMGC_MAPK_ERK3_MAPK6_ST	Q9Y6Q9	NCOA3	Q16659	MAPK6	S543	S543P	543	Missense	central	0	yes	2.188	0.000	EPSD	COSMIC	2.026	Loss
CMGC_MAPK_ERK3_MAPK6_ST	Q9Y6Q9	NCOA3	Q16659	MAPK6	S543	D549N	549	Missense	distal	6	no	2.188	2.180	EPSD	COSMIC	2.026	Down-regulation
CMGC_MAPK_ERK3_MAPK6_ST	Q9Y6Q9	NCOA3	Q16659	MAPK6	S615	P612L	612	Missense	distal	-3	no	2.468	2.473	EPSD	COSMIC	2.026	Up-regulation
CMGC_MAPK_ERK3_MAPK6_ST	Q9Y6Q9	NCOA3	Q16659	MAPK6	S636	R632W	632	Missense	distal	-4	no	3.160	3.162	EPSD	COSMIC	2.026	Up-regulation
CMGC_MAPK_ERK3_MAPK6_ST	Q9Y6Q9	NCOA3	Q16659	MAPK6	S636	S636F	636	Missense	central	0	yes	3.160	0.000	EPSD	COSMIC	2.026	Loss
CMGC_MAPK_ERK3_MAPK6_ST	Q9Y6Q9	NCOA3	Q16659	MAPK6	S640	S636F	636	Missense	distal	-4	no	2.062	2.032	EPSD	COSMIC	2.026	Down-regulation
CMGC_MAPK_ERK3_MAPK6_ST	Q9Y6Q9	NCOA3	Q16659	MAPK6	S652	E648K	648	Missense	distal	-4	no	2.249	2.279	EPSD	COSMIC	2.026	Up-regulation
CMGC_MAPK_ERK3_MAPK6_ST	Q9Y6Q9	NCOA3	Q16659	MAPK6	S655	E648K	648	Missense	distal	-7	no	2.252	2.266	EPSD	COSMIC	2.026	Up-regulation
CMGC_MAPK_ERK3_MAPK6_ST	Q9Y6Q9	NCOA3	Q16659	MAPK6	T706	I701L	701	Missense	distal	-5	no	2.380	2.259	EPSD	COSMIC	2.026	Down-regulation
CMGC_MAPK_ERK3_MAPK6_ST	Q9Y6Q9	NCOA3	Q16659	MAPK6	T706	K708T	708	Missense	proximal	2	no	2.380	2.392	EPSD	COSMIC	2.026	Up-regulation
CMGC_MAPK_ERK3_MAPK6_ST	Q9Y6Q9	NCOA3	Q16659	MAPK6	S857	S863F	863	Missense	distal	6	no	6.156	6.110	PhosphoSitePlus	COSMIC	2.026	Down-regulation
CMGC_MAPK_ERK3_MAPK6_ST	Q9Y6Q9	NCOA3	Q16659	MAPK6	S857	P850S	850	Missense	distal	-7	no	6.156	6.162	PhosphoSitePlus	COSMIC	2.026	Up-regulation
CMGC_MAPK_ERK3_MAPK6_ST	Q9Y6Q9	NCOA3	Q16659	MAPK6	S857	S857C	857	Missense	central	0	yes	6.156	0.000	PhosphoSitePlus	COSMIC	2.026	Loss
CMGC_MAPK_ERK3_MAPK6_ST	Q9Y6Q9	NCOA3	Q16659	MAPK6	T947	G943R	943	Missense	distal	-4	no	2.435	2.424	EPSD	COSMIC	2.026	Down-regulation
CMGC_MAPK_ERK3_MAPK6_ST	Q9Y6Q9	NCOA3	Q16659	MAPK6	T947	G943E	943	Missense	distal	-4	no	2.435	2.409	EPSD	COSMIC	2.026	Down-regulation
CMGC_MAPK_ERK3_MAPK6_ST	Q9Y6Q9	NCOA3	Q16659	MAPK6	T947	N946T	946	Missense	proximal	-1	no	2.435	2.538	EPSD	COSMIC	2.026	Up-regulation
CMGC_MAPK_ERK3_MAPK6_ST	Q9Y6Q9	NCOA3	Q16659	MAPK6	T947	R951I	951	Missense	distal	4	no	2.435	2.316	EPSD	COSMIC	2.026	Down-regulation
CMGC_MAPK_ERK3_MAPK6_ST	Q9Y6Q9	NCOA3	Q16659	MAPK6	T947	N946D	946	Missense	proximal	-1	no	2.435	2.410	EPSD	COSMIC	2.026	Down-regulation
CMGC_MAPK_ERK3_MAPK6_ST	Q9Y6Q9	NCOA3	Q16659	MAPK6	S1033	R1031M	1031	Missense	proximal	-2	no	2.731	2.687	EPSD	COSMIC	2.026	Down-regulation
CMGC_MAPK_ERK3_MAPK6_ST	Q9Y6Q9	NCOA3	Q16659	MAPK6	S1033	L1034M	1034	Missense	proximal	1	no	2.731	2.747	EPSD	COSMIC	2.026	Up-regulation
CMGC_MAPK_ERK3_MAPK6_ST	Q9Y6Q9	NCOA3	Q16659	MAPK6	S1033	L1029V	1029	Missense	distal	-4	no	2.731	2.701	EPSD	COSMIC	2.026	Down-regulation
CMGC_MAPK_ERK3_MAPK6_ST	Q9Y6Q9	NCOA3	Q16659	MAPK6	S1033	R1027M	1027	Missense	distal	-6	no	2.731	2.748	EPSD	COSMIC	2.026	Up-regulation
CMGC_MAPK_ERK3_MAPK6_ST	Q9Y6Q9	NCOA3	Q16659	MAPK6	S1033	L1029M	1029	Missense	distal	-4	no	2.731	2.722	EPSD	COSMIC	2.026	Down-regulation
CMGC_MAPK_ERK3_MAPK6_ST	Q16659	MAPK6	Q16659	MAPK6	S189	W196L	196	Missense	distal	7	no	6.347	6.344	PhosphoSitePlus	COSMIC	2.026	Down-regulation
CMGC_MAPK_ERK3_MAPK6_ST	Q16659	MAPK6	Q16659	MAPK6	S189	H184R	184	Missense	distal	-5	no	6.347	6.206	PhosphoSitePlus	COSMIC	2.026	Down-regulation
CMGC_MAPK_ERK3_MAPK6_ST	O95551	TDP2	Q16659	MAPK6	T92	E91K	91	Missense	proximal	-1	no	2.827	2.873	EPSD	COSMIC	2.026	Up-regulation
CMGC_MAPK_ERK3_MAPK6_ST	O95551	TDP2	Q16659	MAPK6	T92	S98F	98	Missense	distal	6	no	2.827	2.780	EPSD	COSMIC	2.026	Down-regulation
CAMK_CAMK2_CAMK2G_ST	Q13555	CAMK2G	Q13555	CAMK2G	S36	R29C	29	Missense	distal	-7	no	3.968	3.456	EPSD	COSMIC	2.962	Down-regulation
CAMK_CAMK2_CAMK2G_ST	Q13555	CAMK2G	Q13555	CAMK2G	S280	R284H	284	Missense	distal	4	no	6.076	6.025	EPSD;PhosphoSitePlus	COSMIC	2.962	Down-regulation
CAMK_CAMK2_CAMK2G_ST	Q13555	CAMK2G	Q13555	CAMK2G	T287	R284H	284	Missense	distal	-3	no	6.560	5.058	EPSD	COSMIC	2.962	Down-regulation
CAMK_CAMK2_CAMK2G_ST	Q13555	CAMK2G	Q13555	CAMK2G	S325	G327D	327	Missense	proximal	2	no	3.511	3.480	EPSD	COSMIC	2.962	Down-regulation
CAMK_CAMK2_CAMK2G_ST	Q13555	CAMK2G	Q13555	CAMK2G	S335	H339L	339	Missense	distal	4	no	4.110	4.129	EPSD	COSMIC	2.962	Up-regulation
CAMK_CAMK2_CAMK2G_ST	Q13555	CAMK2G	Q13555	CAMK2G	S336	H339L	339	Missense	distal	3	no	3.041	3.084	EPSD	COSMIC	2.962	Up-regulation
CAMK_CAMK2_CAMK2G_ST	Q13555	CAMK2G	Q13555	CAMK2G	T408	G413D	413	Missense	distal	5	no	2.871	2.962	EPSD	COSMIC	2.962	Gain
CAMK_CAMK2_CAMK2G_ST	Q13555	CAMK2G	Q13555	CAMK2G	T408	A409V	409	Missense	proximal	1	no	2.871	2.981	EPSD	COSMIC	2.962	Gain
CAMK_CAMK2_CAMK2G_ST	Q13555	CAMK2G	Q13555	CAMK2G	S423	Q417L	417	Missense	distal	-6	no	3.576	3.246	EPSD	COSMIC	2.962	Down-regulation
CAMK_CAMK2_CAMK2G_ST	Q13555	CAMK2G	Q13555	CAMK2G	S423	M425I	425	Missense	proximal	2	no	3.576	3.619	EPSD	COSMIC	2.962	Up-regulation
CAMK_CAMK2_CAMK2G_ST	Q13555	CAMK2G	Q13555	CAMK2G	S423	R426Q	426	Missense	distal	3	no	3.576	3.419	EPSD	COSMIC	2.962	Down-regulation
CAMK_CAMK2_CAMK2G_ST	P98082	DAB2	Q13555	CAMK2G	S310	P303A	303	Missense	distal	-7	no	3.389	3.502	EPSD	COSMIC	2.962	Up-regulation
CAMK_CAMK2_CAMK2G_ST	P98082	DAB2	Q13555	CAMK2G	S310	F311L	311	Missense	proximal	1	no	3.389	3.337	EPSD	COSMIC;CCLE	2.962	Down-regulation
CAMK_CAMK2_CAMK2G_ST	P98082	DAB2	Q13555	CAMK2G	S310	T307A	307	Missense	distal	-3	no	3.389	2.912	EPSD	COSMIC	2.962	Loss
CAMK_CAMK2_CAMK2G_ST	P98082	DAB2	Q13555	CAMK2G	S310	Q305K	305	Missense	distal	-5	no	3.389	3.414	EPSD	COSMIC	2.962	Up-regulation
CAMK_CAMK2_CAMK2G_ST	P98082	DAB2	Q13555	CAMK2G	S313	F311L	311	Missense	proximal	-2	no	3.278	3.347	EPSD	COSMIC;CCLE	2.962	Up-regulation
CAMK_CAMK2_CAMK2G_ST	P98082	DAB2	Q13555	CAMK2G	S313	Q319P	319	Missense	distal	6	no	3.278	2.875	EPSD	COSMIC	2.962	Loss
CAMK_CAMK2_CAMK2G_ST	P98082	DAB2	Q13555	CAMK2G	S313	T307A	307	Missense	distal	-6	no	3.278	3.271	EPSD	COSMIC	2.962	Down-regulation
CAMK_CAMK2_CAMK2G_ST	P98082	DAB2	Q13555	CAMK2G	S456	P462S	462	Missense	distal	6	no	3.194	3.623	EPSD	COSMIC	2.962	Up-regulation
CAMK_CAMK2_CAMK2G_ST	P98082	DAB2	Q13555	CAMK2G	S456	D452G	452	Missense	distal	-4	no	3.194	3.207	EPSD	COSMIC	2.962	Up-regulation
CAMK_CAMK2_CAMK2G_ST	P98082	DAB2	Q13555	CAMK2G	S456	A460S	460	Missense	distal	4	no	3.194	3.193	EPSD	COSMIC;GDSC;CCLE	2.962	Down-regulation
CAMK_CAMK2_CAMK2G_ST	P98082	DAB2	Q13555	CAMK2G	S456	P462L	462	Missense	distal	6	no	3.194	2.893	EPSD	COSMIC	2.962	Loss
CAMK_CAMK2_CAMK2G_ST	P98082	DAB2	Q13555	CAMK2G	S456	A450T	450	Missense	distal	-6	no	3.194	3.201	EPSD	COSMIC	2.962	Up-regulation
CAMK_CAMK2_CAMK2G_ST	P98082	DAB2	Q13555	CAMK2G	S723	V722I	722	Missense	proximal	-1	no	6.673	6.510	PhosphoSitePlus	COSMIC	2.962	Down-regulation
CAMK_CAMK2_CAMK2G_ST	P98082	DAB2	Q13555	CAMK2G	S723	Q721K	721	Missense	proximal	-2	no	6.673	6.757	PhosphoSitePlus	COSMIC	2.962	Up-regulation
CAMK_CAMK2_CAMK2G_ST	P98082	DAB2	Q13555	CAMK2G	S723	L724M	724	Missense	proximal	1	no	6.673	6.763	PhosphoSitePlus	COSMIC	2.962	Up-regulation
CAMK_CAMK2_CAMK2G_ST	P98082	DAB2	Q13555	CAMK2G	S723	K716N	716	Missense	distal	-7	no	6.673	6.342	PhosphoSitePlus	COSMIC	2.962	Down-regulation
CAMK_CAMK2_CAMK2G_ST	P98082	DAB2	Q13555	CAMK2G	S723	Q721H	721	Missense	proximal	-2	no	6.673	6.604	PhosphoSitePlus	COSMIC	2.962	Down-regulation
CAMK_CAMK2_CAMK2G_ST	P98082	DAB2	Q13555	CAMK2G	S723	P725S	725	Missense	proximal	2	no	6.673	6.676	PhosphoSitePlus	COSMIC	2.962	Up-regulation
CAMK_CAMK2_CAMK2G_ST	P98082	DAB2	Q13555	CAMK2G	S723	A718D	718	Missense	distal	-5	no	6.673	6.794	PhosphoSitePlus	COSMIC	2.962	Up-regulation
CAMK_CAMK2_CAMK2G_ST	P98082	DAB2	Q13555	CAMK2G	S723	A718S	718	Missense	distal	-5	no	6.673	6.630	PhosphoSitePlus	COSMIC	2.962	Down-regulation
CAMK_CAMK2_CAMK2G_ST	P98082	DAB2	Q13555	CAMK2G	T727	V722I	722	Missense	distal	-5	no	3.822	3.948	EPSD	COSMIC	2.962	Up-regulation
CAMK_CAMK2_CAMK2G_ST	P98082	DAB2	Q13555	CAMK2G	T727	Q721K	721	Missense	distal	-6	no	3.822	3.758	EPSD	COSMIC	2.962	Down-regulation
CAMK_CAMK2_CAMK2G_ST	P98082	DAB2	Q13555	CAMK2G	T727	L724M	724	Missense	distal	-3	no	3.822	2.843	EPSD	COSMIC	2.962	Loss
CAMK_CAMK2_CAMK2G_ST	P98082	DAB2	Q13555	CAMK2G	T727	Q721H	721	Missense	distal	-6	no	3.822	3.648	EPSD	COSMIC	2.962	Down-regulation
CAMK_CAMK2_CAMK2G_ST	P98082	DAB2	Q13555	CAMK2G	T727	P725S	725	Missense	proximal	-2	no	3.822	3.724	EPSD	COSMIC	2.962	Down-regulation
CAMK_CAMK2_CAMK2G_ST	Q16625	OCLN	Q13555	CAMK2G	S159	S159R	159	Missense	central	0	yes	3.044	0.000	EPSD	COSMIC	2.962	Loss
CAMK_CAMK2_CAMK2G_ST	Q16625	OCLN	Q13555	CAMK2G	S159	V160I	160	Missense	proximal	1	no	3.044	2.892	EPSD	COSMIC	2.962	Loss
CAMK_CAMK2_CAMK2G_ST	Q16625	OCLN	Q13555	CAMK2G	S159	A152S	152	Missense	distal	-7	no	3.044	3.512	EPSD	COSMIC	2.962	Up-regulation
CAMK_CAMK2_CAMK2G_ST	Q16625	OCLN	Q13555	CAMK2G	S159	R162I	162	Missense	distal	3	no	3.044	3.083	EPSD	COSMIC	2.962	Up-regulation
CAMK_CAMK2_CAMK2G_ST	Q16625	OCLN	Q13555	CAMK2G	S159	V157F	157	Missense	proximal	-2	no	3.044	3.004	EPSD	COSMIC	2.962	Down-regulation
CAMK_CAMK2_CAMK2G_ST	O95180	CACNA1H	Q13555	CAMK2G	S475	R469H	469	Missense	distal	-6	no	3.189	3.098	EPSD	COSMIC	2.962	Down-regulation
CAMK_CAMK2_CAMK2G_ST	O95180	CACNA1H	Q13555	CAMK2G	S475	K470N	470	Missense	distal	-5	no	3.189	3.317	EPSD	COSMIC	2.962	Up-regulation
CAMK_CAMK2_CAMK2G_ST	O95180	CACNA1H	Q13555	CAMK2G	S475	R474H	474	Missense	proximal	-1	no	3.189	2.990	EPSD	COSMIC;GDSC;CCLE	2.962	Down-regulation
CAMK_CAMK2_CAMK2G_ST	O95180	CACNA1H	Q13555	CAMK2G	S475	S475N	475	Missense	central	0	yes	3.189	0.000	EPSD	COSMIC;GDSC;CCLE	2.962	Loss
CAMK_CAMK2_CAMK2G_ST	O95180	CACNA1H	Q13555	CAMK2G	S558	G554C	554	Missense	distal	-4	no	3.040	3.000	EPSD	COSMIC	2.962	Down-regulation
CAMK_CAMK2_CAMK2G_ST	O95180	CACNA1H	Q13555	CAMK2G	S558	V551I	551	Missense	distal	-7	no	3.040	3.030	EPSD	COSMIC	2.962	Down-regulation
CAMK_CAMK2_CAMK2G_ST	O95180	CACNA1H	Q13555	CAMK2G	S558	A555S	555	Missense	distal	-3	no	3.040	2.806	EPSD	COSMIC	2.962	Loss
CAMK_CAMK2_CAMK2G_ST	O95180	CACNA1H	Q13555	CAMK2G	S558	G554V	554	Missense	distal	-4	no	3.040	2.772	EPSD	COSMIC	2.962	Loss
CAMK_CAMK2_CAMK2G_ST	O95180	CACNA1H	Q13555	CAMK2G	S558	R564H	564	Missense	distal	6	no	3.040	2.565	EPSD	COSMIC	2.962	Loss
CAMK_CAMK2_CAMK2G_ST	O95180	CACNA1H	Q13555	CAMK2G	S1091	P1088T	1088	Missense	distal	-3	no	1.977	3.021	EPSD	COSMIC	2.962	Gain
CAMK_CAMK2_CAMK2G_ST	O95180	CACNA1H	Q13555	CAMK2G	S1107	G1106D	1106	Missense	proximal	-1	no	3.048	3.080	EPSD	COSMIC	2.962	Up-regulation
CAMK_CAMK2_CAMK2G_ST	O95180	CACNA1H	Q13555	CAMK2G	S1107	D1112A	1112	Missense	distal	5	no	3.048	3.052	EPSD	COSMIC	2.962	Up-regulation
CAMK_CAMK2_CAMK2G_ST	O95180	CACNA1H	Q13555	CAMK2G	S1168	G1161E	1161	Missense	distal	-7	no	3.279	3.339	EPSD	COSMIC;GDSC;CCLE	2.962	Up-regulation
CAMK_CAMK2_CAMK2G_ST	O95180	CACNA1H	Q13555	CAMK2G	S1426	P1429L	1429	Missense	distal	3	no	2.914	3.094	EPSD	COSMIC;GDSC;CCLE	2.962	Gain
CAMK_CAMK2_CAMK2G_ST	O95180	CACNA1H	Q13555	CAMK2G	T1806	T1800M	1800	Missense	distal	-6	no	2.948	2.970	EPSD	COSMIC	2.962	Gain
CAMK_CAMK2_CAMK2G_ST	O95180	CACNA1H	Q13555	CAMK2G	S1905	P1906L	1906	Missense	proximal	1	no	4.809	4.697	EPSD	COSMIC;GDSC;CCLE	2.962	Down-regulation
CAMK_CAMK2_CAMK2G_ST	O95180	CACNA1H	Q13555	CAMK2G	S1905	P1900L	1900	Missense	distal	-5	no	4.809	4.854	EPSD	COSMIC	2.962	Up-regulation
CAMK_CAMK2_CAMK2G_ST	O95180	CACNA1H	Q13555	CAMK2G	S1920	V1919M	1919	Missense	proximal	-1	no	3.175	3.072	EPSD	COSMIC	2.962	Down-regulation
CAMK_CAMK2_CAMK2G_ST	O95180	CACNA1H	Q13555	CAMK2G	S1920	R1917H	1917	Missense	distal	-3	no	3.175	1.673	EPSD	COSMIC	2.962	Loss
CAMK_CAMK2_CAMK2G_ST	O95180	CACNA1H	Q13555	CAMK2G	S1920	V1921M	1921	Missense	proximal	1	no	3.175	3.094	EPSD	COSMIC	2.962	Down-regulation
CAMK_CAMK2_CAMK2G_ST	O95180	CACNA1H	Q13555	CAMK2G	S1920	V1915M	1915	Missense	distal	-5	no	3.175	3.263	EPSD	COSMIC	2.962	Up-regulation
CAMK_CAMK2_CAMK2G_ST	O95180	CACNA1H	Q13555	CAMK2G	S2137	R2130Q	2130	Missense	distal	-7	no	3.954	3.484	EPSD	COSMIC	2.962	Down-regulation
Atypical_PDHK_PDHK_PDK1_ST	P08559	PDHA1	Q15118	PDK1	S232	S239F	239	Missense	distal	7	no	0.299	0.301	EPSD;PhosphoSitePlus	COSMIC	0.124	Up-regulation
Atypical_PDHK_PDHK_PDK1_ST	P08559	PDHA1	Q15118	PDK1	S232	T231M	231	Missense	proximal	-1	no	0.299	0.297	EPSD;PhosphoSitePlus	COSMIC	0.124	Down-regulation
Atypical_PDHK_PDHK_PDK1_ST	P08559	PDHA1	Q15118	PDK1	S232	R226H	226	Missense	distal	-6	no	0.299	0.303	EPSD;PhosphoSitePlus	COSMIC	0.124	Up-regulation
Atypical_PDHK_PDHK_PDK1_ST	P08559	PDHA1	Q15118	PDK1	S232	S232F	232	Missense	central	0	yes	0.299	0.000	EPSD;PhosphoSitePlus	COSMIC	0.124	Loss
Atypical_PDHK_PDHK_PDK1_ST	P08559	PDHA1	Q15118	PDK1	S232	E234K	234	Missense	proximal	2	no	0.299	0.291	EPSD;PhosphoSitePlus	COSMIC	0.124	Down-regulation
Atypical_PDHK_PDHK_PDK1_ST	P08559	PDHA1	Q15118	PDK1	S293	Y287H	287	Missense	distal	-6	no	0.327	0.324	PhosphoSitePlus;EPSD	COSMIC	0.124	Down-regulation
Atypical_PDHK_PDHK_PDK1_ST	P08559	PDHA1	Q15118	PDK1	S293	R288C	288	Missense	distal	-5	no	0.327	0.322	PhosphoSitePlus;EPSD	COSMIC	0.124	Down-regulation
Atypical_PDHK_PDHK_PDK1_ST	P08559	PDHA1	Q15118	PDK1	S300	R302S	302	Missense	proximal	2	no	0.299	0.307	EPSD;PhosphoSitePlus	COSMIC	0.124	Up-regulation
Atypical_PDHK_PDHK_PDK1_ST	P08559	PDHA1	Q15118	PDK1	S300	R304Q	304	Missense	distal	4	no	0.299	0.315	EPSD;PhosphoSitePlus	COSMIC;GDSC;CCLE	0.124	Up-regulation
Atypical_PDHK_PDHK_PDK1_ST	P08559	PDHA1	Q15118	PDK1	S300	R302C	302	Missense	proximal	2	no	0.299	0.311	EPSD;PhosphoSitePlus	COSMIC	0.124	Up-regulation
Atypical_PDHK_PDHK_PDK1_ST	P08559	PDHA1	Q15118	PDK1	S300	R302L	302	Missense	proximal	2	no	0.299	0.304	EPSD;PhosphoSitePlus	COSMIC	0.124	Up-regulation
Atypical_PDHK_PDHK_PDK1_ST	P29803	PDHA2	Q15118	PDK1	S291	R286H	286	Missense	distal	-5	no	0.357	0.353	EPSD;PhosphoSitePlus	COSMIC	0.124	Down-regulation
Atypical_PDHK_PDHK_PDK1_ST	P29803	PDHA2	Q15118	PDK1	S291	T284I	284	Missense	distal	-7	no	0.357	0.359	EPSD;PhosphoSitePlus	COSMIC	0.124	Up-regulation
Atypical_PDHK_PDHK_PDK1_ST	P29803	PDHA2	Q15118	PDK1	S291	T284P	284	Missense	distal	-7	no	0.357	0.358	EPSD;PhosphoSitePlus	COSMIC	0.124	Up-regulation
Atypical_PDHK_PDHK_PDK1_ST	P29803	PDHA2	Q15118	PDK1	S293	R286H	286	Missense	distal	-7	no	0.147	0.146	EPSD	COSMIC	0.124	Down-regulation
Atypical_PDHK_PDHK_PDK1_ST	P29803	PDHA2	Q15118	PDK1	S293	D294Y	294	Missense	proximal	1	no	0.147	0.213	EPSD	COSMIC;GDSC;CCLE	0.124	Up-regulation
Atypical_PDHK_PDHK_PDK1_ST	P29803	PDHA2	Q15118	PDK1	S298	E304K	304	Missense	distal	6	no	0.318	0.315	PhosphoSitePlus;EPSD	COSMIC	0.124	Down-regulation
Atypical_PDHK_PDHK_PDK1_ST	P29803	PDHA2	Q15118	PDK1	S298	D294Y	294	Missense	distal	-4	no	0.318	0.319	PhosphoSitePlus;EPSD	COSMIC;GDSC;CCLE	0.124	Up-regulation
CMGC_MAPK_JNK_MAPK8_ST	Q96EB6	SIRT1	P45983	MAPK8	S14	S14P	14	Missense	central	0	yes	7.514	0.000	EPSD	COSMIC	2.638	Loss
CMGC_MAPK_JNK_MAPK8_ST	Q96EB6	SIRT1	P45983	MAPK8	T530	E536V	536	Missense	distal	6	no	7.572	7.492	EPSD;PhosphoSitePlus	COSMIC	2.638	Down-regulation
CMGC_MAPK_JNK_MAPK8_ST	Q96EB6	SIRT1	P45983	MAPK8	S540	E542Q	542	Missense	proximal	2	no	7.428	7.298	EPSD	COSMIC	2.638	Down-regulation
CMGC_MAPK_JNK_MAPK8_ST	Q96EB6	SIRT1	P45983	MAPK8	S540	E536V	536	Missense	distal	-4	no	7.428	6.539	EPSD	COSMIC	2.638	Down-regulation
CMGC_MAPK_JNK_MAPK8_ST	Q96EB6	SIRT1	P45983	MAPK8	S545	E542Q	542	Missense	distal	-3	no	6.659	6.502	EPSD	COSMIC	2.638	Down-regulation
CMGC_MAPK_JNK_MAPK8_ST	Q96EB6	SIRT1	P45983	MAPK8	S545	S549C	549	Missense	distal	4	no	6.659	6.328	EPSD	COSMIC	2.638	Down-regulation
CMGC_MAPK_JNK_MAPK8_ST	Q96EB6	SIRT1	P45983	MAPK8	S682	E687K	687	Missense	distal	5	no	7.387	7.378	EPSD	COSMIC;GDSC;CCLE	2.638	Down-regulation
CMGC_MAPK_JNK_MAPK8_ST	P46937	YAP1	P45983	MAPK8	T119	A125G	125	Missense	distal	6	no	8.541	8.487	EPSD	COSMIC	2.638	Down-regulation
CMGC_MAPK_JNK_MAPK8_ST	P46937	YAP1	P45983	MAPK8	S128	L132R	132	Missense	distal	4	no	8.498	8.565	EPSD	COSMIC	2.638	Up-regulation
CMGC_MAPK_JNK_MAPK8_ST	P46937	YAP1	P45983	MAPK8	S128	Q133H	133	Missense	distal	5	no	8.498	8.528	EPSD	COSMIC	2.638	Up-regulation
CMGC_MAPK_JNK_MAPK8_ST	P46937	YAP1	P45983	MAPK8	S128	S127F	127	Missense	proximal	-1	no	8.498	8.468	EPSD	COSMIC	2.638	Down-regulation
CMGC_MAPK_JNK_MAPK8_ST	P46937	YAP1	P45983	MAPK8	S128	A125G	125	Missense	distal	-3	no	8.498	8.181	EPSD	COSMIC	2.638	Down-regulation
CMGC_MAPK_JNK_MAPK8_ST	P46937	YAP1	P45983	MAPK8	S138	L132R	132	Missense	distal	-6	no	7.515	7.490	EPSD	COSMIC	2.638	Down-regulation
CMGC_MAPK_JNK_MAPK8_ST	P46937	YAP1	P45983	MAPK8	S138	G140W	140	Missense	proximal	2	no	7.515	7.403	EPSD	COSMIC	2.638	Down-regulation
CMGC_MAPK_JNK_MAPK8_ST	P46937	YAP1	P45983	MAPK8	S138	T145S	145	Missense	distal	7	no	7.515	7.507	EPSD	COSMIC	2.638	Down-regulation
CMGC_MAPK_JNK_MAPK8_ST	P46937	YAP1	P45983	MAPK8	S138	P139F	139	Missense	proximal	1	no	7.515	-0.658	EPSD	COSMIC	2.638	Loss
CMGC_MAPK_JNK_MAPK8_ST	P46937	YAP1	P45983	MAPK8	S138	Q133H	133	Missense	distal	-5	no	7.515	7.734	EPSD	COSMIC	2.638	Up-regulation
CMGC_MAPK_JNK_MAPK8_ST	P46937	YAP1	P45983	MAPK8	T143	G140W	140	Missense	distal	-3	no	6.792	6.683	EPSD	COSMIC	2.638	Down-regulation
CMGC_MAPK_JNK_MAPK8_ST	P46937	YAP1	P45983	MAPK8	T143	T145S	145	Missense	proximal	2	no	6.792	6.789	EPSD	COSMIC	2.638	Down-regulation
CMGC_MAPK_JNK_MAPK8_ST	P46937	YAP1	P45983	MAPK8	T143	P139F	139	Missense	distal	-4	no	6.792	6.519	EPSD	COSMIC	2.638	Down-regulation
CMGC_MAPK_JNK_MAPK8_ST	P46937	YAP1	P45983	MAPK8	T154	A152T	152	Missense	proximal	-2	no	7.506	7.476	PhosphoSitePlus;EPSD	COSMIC	2.638	Down-regulation
CMGC_MAPK_JNK_MAPK8_ST	P46937	YAP1	P45983	MAPK8	T154	P151A	151	Missense	distal	-3	no	7.506	7.703	PhosphoSitePlus;EPSD	COSMIC	2.638	Up-regulation
CMGC_MAPK_JNK_MAPK8_ST	P46937	YAP1	P45983	MAPK8	T154	L160H	160	Missense	distal	6	no	7.506	7.529	PhosphoSitePlus;EPSD	COSMIC	2.638	Up-regulation
CMGC_MAPK_JNK_MAPK8_ST	P46937	YAP1	P45983	MAPK8	S217	V212I	212	Missense	distal	-5	no	8.888	8.567	EPSD	COSMIC	2.638	Down-regulation
CMGC_MAPK_JNK_MAPK8_ST	P46937	YAP1	P45983	MAPK8	S217	M210I	210	Missense	distal	-7	no	8.888	8.881	EPSD	COSMIC	2.638	Down-regulation
CMGC_MAPK_JNK_MAPK8_ST	P46937	YAP1	P45983	MAPK8	S289	P284L	284	Missense	distal	-5	no	7.444	7.804	EPSD	COSMIC	2.638	Up-regulation
CMGC_MAPK_JNK_MAPK8_ST	P46937	YAP1	P45983	MAPK8	S340	A338T	338	Missense	proximal	-2	no	11.219	11.189	EPSD	COSMIC	2.638	Down-regulation
CMGC_MAPK_JNK_MAPK8_ST	P46937	YAP1	P45983	MAPK8	S340	S340A	340	Missense	central	0	yes	11.219	0.000	EPSD	COSMIC;GDSC	2.638	Loss
CMGC_MAPK_JNK_MAPK8_ST	P46937	YAP1	P45983	MAPK8	T354	L352P	352	Missense	proximal	-2	no	2.537	2.730	EPSD	COSMIC	2.638	Gain
CMGC_MAPK_JNK_MAPK8_ST	P46937	YAP1	P45983	MAPK8	S367	S371F	371	Missense	distal	4	no	6.322	5.864	EPSD	COSMIC	2.638	Down-regulation
CMGC_MAPK_JNK_MAPK8_ST	P46937	YAP1	P45983	MAPK8	S367	S367F	367	Missense	central	0	yes	6.322	0.000	EPSD	COSMIC	2.638	Loss
CMGC_MAPK_JNK_MAPK8_ST	P46937	YAP1	P45983	MAPK8	S382	N380T	380	Missense	proximal	-2	no	2.581	2.725	EPSD	COSMIC	2.638	Gain
CMGC_MAPK_JNK_MAPK8_ST	P46937	YAP1	P45983	MAPK8	S382	L386P	386	Missense	distal	4	no	2.581	2.988	EPSD	COSMIC	2.638	Gain
CMGC_MAPK_JNK_MAPK8_ST	P46937	YAP1	P45983	MAPK8	S382	T376P	376	Missense	distal	-6	no	2.581	2.645	EPSD	COSMIC	2.638	Gain
CMGC_MAPK_JNK_MAPK8_ST	P46937	YAP1	P45983	MAPK8	S382	M377V	377	Missense	distal	-5	no	2.581	2.665	EPSD	COSMIC	2.638	Gain
CMGC_MAPK_JNK_MAPK8_ST	P46937	YAP1	P45983	MAPK8	S400	D399G	399	Missense	proximal	-1	no	2.744	2.733	EPSD	COSMIC	2.638	Down-regulation
CMGC_MAPK_JNK_MAPK8_ST	P46937	YAP1	P45983	MAPK8	S400	E396K	396	Missense	distal	-4	no	2.744	3.000	EPSD	COSMIC	2.638	Up-regulation
CMGC_MAPK_JNK_MAPK8_ST	P46937	YAP1	P45983	MAPK8	S400	D399H	399	Missense	proximal	-1	no	2.744	2.737	EPSD	COSMIC	2.638	Down-regulation
CMGC_MAPK_JNK_MAPK8_ST	P46937	YAP1	P45983	MAPK8	S400	D395G	395	Missense	distal	-5	no	2.744	2.895	EPSD	COSMIC	2.638	Up-regulation
CMGC_MAPK_JNK_MAPK8_ST	P46937	YAP1	P45983	MAPK8	T412	N418T	418	Missense	distal	6	no	7.555	7.617	EPSD	COSMIC	2.638	Up-regulation
CMGC_MAPK_JNK_MAPK8_ST	P46937	YAP1	P45983	MAPK8	T412	F416L	416	Missense	distal	4	no	7.555	7.581	EPSD	COSMIC	2.638	Up-regulation
CMGC_MAPK_JNK_MAPK8_ST	P46937	YAP1	P45983	MAPK8	T412	R411Q	411	Missense	proximal	-1	no	7.555	7.575	EPSD	COSMIC	2.638	Up-regulation
CMGC_MAPK_JNK_MAPK8_ST	P36956	SREBF1	P45983	MAPK8	T105	P99S	99	Missense	distal	-6	no	5.927	5.838	EPSD	COSMIC	2.638	Down-regulation
CMGC_MAPK_JNK_MAPK8_ST	P36956	SREBF1	P45983	MAPK8	T105	S112A	112	Missense	distal	7	no	5.927	5.933	EPSD	COSMIC	2.638	Up-regulation
CMGC_MAPK_JNK_MAPK8_ST	P36956	SREBF1	P45983	MAPK8	T105	P111L	111	Missense	distal	6	no	5.927	5.880	EPSD	COSMIC	2.638	Down-regulation
CMGC_MAPK_JNK_MAPK8_ST	P36956	SREBF1	P45983	MAPK8	T105	Y110C	110	Missense	distal	5	no	5.927	5.874	EPSD	COSMIC	2.638	Down-regulation
CMGC_MAPK_JNK_MAPK8_ST	P36956	SREBF1	P45983	MAPK8	T105	P106H	106	Missense	proximal	1	no	5.927	-1.988	EPSD	COSMIC	2.638	Loss
CMGC_MAPK_JNK_MAPK8_ST	P36956	SREBF1	P45983	MAPK8	S112	S112A	112	Missense	central	0	yes	2.866	0.000	EPSD	COSMIC	2.638	Loss
CMGC_MAPK_JNK_MAPK8_ST	P36956	SREBF1	P45983	MAPK8	S112	P111L	111	Missense	proximal	-1	no	2.866	2.848	EPSD	COSMIC	2.638	Down-regulation
CMGC_MAPK_JNK_MAPK8_ST	P36956	SREBF1	P45983	MAPK8	S112	Y110C	110	Missense	proximal	-2	no	2.866	2.931	EPSD	COSMIC	2.638	Up-regulation
CMGC_MAPK_JNK_MAPK8_ST	P36956	SREBF1	P45983	MAPK8	S112	G119W	119	Missense	distal	7	no	2.866	2.878	EPSD	COSMIC	2.638	Up-regulation
CMGC_MAPK_JNK_MAPK8_ST	P36956	SREBF1	P45983	MAPK8	S112	P106H	106	Missense	distal	-6	no	2.866	2.911	EPSD	COSMIC	2.638	Up-regulation
CMGC_MAPK_JNK_MAPK8_ST	P36956	SREBF1	P45983	MAPK8	S117	K123E	123	Missense	distal	6	no	8.727	8.711	EPSD;PhosphoSitePlus	COSMIC	2.638	Down-regulation
CMGC_MAPK_JNK_MAPK8_ST	P36956	SREBF1	P45983	MAPK8	S117	S112A	112	Missense	distal	-5	no	8.727	8.711	EPSD;PhosphoSitePlus	COSMIC	2.638	Down-regulation
CMGC_MAPK_JNK_MAPK8_ST	P36956	SREBF1	P45983	MAPK8	S117	P111L	111	Missense	distal	-6	no	8.727	8.818	EPSD;PhosphoSitePlus	COSMIC	2.638	Up-regulation
CMGC_MAPK_JNK_MAPK8_ST	P36956	SREBF1	P45983	MAPK8	S117	Y110C	110	Missense	distal	-7	no	8.727	8.718	EPSD;PhosphoSitePlus	COSMIC	2.638	Down-regulation
CMGC_MAPK_JNK_MAPK8_ST	P36956	SREBF1	P45983	MAPK8	S117	G119W	119	Missense	proximal	2	no	8.727	8.616	EPSD;PhosphoSitePlus	COSMIC	2.638	Down-regulation
CMGC_MAPK_JNK_MAPK8_ST	P36956	SREBF1	P45983	MAPK8	T426	E420K	420	Missense	distal	-6	no	8.292	8.287	EPSD	COSMIC	2.638	Down-regulation
CMGC_MAPK_JNK_MAPK8_ST	P36956	SREBF1	P45983	MAPK8	T426	D423G	423	Missense	distal	-3	no	8.292	8.198	EPSD	COSMIC	2.638	Down-regulation
CMGC_MAPK_JNK_MAPK8_ST	P36956	SREBF1	P45983	MAPK8	S434	P440H	440	Missense	distal	6	no	9.498	9.474	EPSD	COSMIC	2.638	Down-regulation
CMGC_MAPK_JNK_MAPK8_ST	P36956	SREBF1	P45983	MAPK8	S439	L443F	443	Missense	distal	4	no	7.359	7.333	EPSD	COSMIC	2.638	Down-regulation
CMGC_MAPK_JNK_MAPK8_ST	P36956	SREBF1	P45983	MAPK8	S439	P440H	440	Missense	proximal	1	no	7.359	-0.557	EPSD	COSMIC	2.638	Loss
CMGC_MAPK_JNK_MAPK8_ST	P36956	SREBF1	P45983	MAPK8	S461	G454D	454	Missense	distal	-7	no	8.677	8.672	EPSD	COSMIC	2.638	Down-regulation
CMGC_MAPK_JNK_MAPK8_ST	P36956	SREBF1	P45983	MAPK8	S461	P459H	459	Missense	proximal	-2	no	8.677	8.493	EPSD	COSMIC	2.638	Down-regulation
CMGC_MAPK_JNK_MAPK8_ST	P36956	SREBF1	P45983	MAPK8	S524	S520N	520	Missense	distal	-4	no	7.341	6.467	EPSD	COSMIC	2.638	Down-regulation
CMGC_MAPK_JNK_MAPK8_ST	P36956	SREBF1	P45983	MAPK8	S524	G531A	531	Missense	distal	7	no	7.341	7.282	EPSD	COSMIC	2.638	Down-regulation
CMGC_MAPK_JNK_MAPK8_ST	P36956	SREBF1	P45983	MAPK8	S524	H523N	523	Missense	proximal	-1	no	7.341	7.333	EPSD	COSMIC	2.638	Down-regulation
CMGC_MAPK_JNK_MAPK8_ST	P36956	SREBF1	P45983	MAPK8	S1049	T1051I	1051	Missense	proximal	2	no	8.340	8.215	EPSD	COSMIC	2.638	Down-regulation
CMGC_MAPK_JNK_MAPK8_ST	P36956	SREBF1	P45983	MAPK8	S1049	A1046V	1046	Missense	distal	-3	no	8.340	7.911	EPSD	COSMIC	2.638	Down-regulation
CMGC_MAPK_JNK_MAPK8_ST	P36956	SREBF1	P45983	MAPK8	S1049	G1047W	1047	Missense	proximal	-2	no	8.340	8.333	EPSD	COSMIC	2.638	Down-regulation
CMGC_MAPK_JNK_MAPK8_ST	P10636	MAPT	P45983	MAPK8	T69	E62K	62	Missense	distal	-7	no	8.525	8.522	EPSD	COSMIC	2.638	Down-regulation
CMGC_MAPK_JNK_MAPK8_ST	P10636	MAPT	P45983	MAPK8	T111	I108V	108	Missense	distal	-3	no	7.410	7.176	EPSD	COSMIC	2.638	Down-regulation
CMGC_MAPK_JNK_MAPK8_ST	P10636	MAPT	P45983	MAPK8	T111	G107R	107	Missense	distal	-4	no	7.410	7.498	EPSD	COSMIC	2.638	Up-regulation
CMGC_MAPK_JNK_MAPK8_ST	P10636	MAPT	P45983	MAPK8	S228	S227N	227	Missense	proximal	-1	no	9.293	9.265	EPSD	COSMIC	2.638	Down-regulation
CMGC_MAPK_JNK_MAPK8_ST	P10636	MAPT	P45983	MAPK8	S228	S227I	227	Missense	proximal	-1	no	9.293	9.281	EPSD	COSMIC	2.638	Down-regulation
CMGC_MAPK_JNK_MAPK8_ST	P10636	MAPT	P45983	MAPK8	S228	E226K	226	Missense	proximal	-2	no	9.293	9.290	EPSD	COSMIC	2.638	Down-regulation
CMGC_MAPK_JNK_MAPK8_ST	P10636	MAPT	P45983	MAPK8	S228	Q230R	230	Missense	proximal	2	no	9.293	9.118	EPSD	COSMIC	2.638	Down-regulation
CMGC_MAPK_JNK_MAPK8_ST	P10636	MAPT	P45983	MAPK8	S228	P233S	233	Missense	distal	5	no	9.293	9.210	EPSD	COSMIC	2.638	Down-regulation
CMGC_MAPK_JNK_MAPK8_ST	P10636	MAPT	P45983	MAPK8	S228	D225E	225	Missense	distal	-3	no	9.293	9.532	EPSD	COSMIC	2.638	Up-regulation
CMGC_MAPK_JNK_MAPK8_ST	P10636	MAPT	P45983	MAPK8	S228	S227G	227	Missense	proximal	-1	no	9.293	9.269	EPSD	COSMIC	2.638	Down-regulation
CMGC_MAPK_JNK_MAPK8_ST	P10636	MAPT	P45983	MAPK8	S228	S235L	235	Missense	distal	7	no	9.293	9.371	EPSD	COSMIC	2.638	Up-regulation
CMGC_MAPK_JNK_MAPK8_ST	P10636	MAPT	P45983	MAPK8	S232	S227N	227	Missense	distal	-5	no	7.907	8.339	EPSD	COSMIC	2.638	Up-regulation
CMGC_MAPK_JNK_MAPK8_ST	P10636	MAPT	P45983	MAPK8	S232	S227I	227	Missense	distal	-5	no	7.907	8.111	EPSD	COSMIC	2.638	Up-regulation
CMGC_MAPK_JNK_MAPK8_ST	P10636	MAPT	P45983	MAPK8	S232	A237T	237	Missense	distal	5	no	7.907	7.905	EPSD	COSMIC	2.638	Down-regulation
CMGC_MAPK_JNK_MAPK8_ST	P10636	MAPT	P45983	MAPK8	S232	E226K	226	Missense	distal	-6	no	7.907	7.902	EPSD	COSMIC	2.638	Down-regulation
CMGC_MAPK_JNK_MAPK8_ST	P10636	MAPT	P45983	MAPK8	S232	Q230R	230	Missense	proximal	-2	no	7.907	7.833	EPSD	COSMIC	2.638	Down-regulation
CMGC_MAPK_JNK_MAPK8_ST	P10636	MAPT	P45983	MAPK8	S232	S238P	238	Missense	distal	6	no	7.907	7.883	EPSD	COSMIC	2.638	Down-regulation
CMGC_MAPK_JNK_MAPK8_ST	P10636	MAPT	P45983	MAPK8	S232	P233S	233	Missense	proximal	1	no	7.907	0.178	EPSD	COSMIC	2.638	Loss
CMGC_MAPK_JNK_MAPK8_ST	P10636	MAPT	P45983	MAPK8	S232	S238F	238	Missense	distal	6	no	7.907	7.838	EPSD	COSMIC	2.638	Down-regulation
CMGC_MAPK_JNK_MAPK8_ST	P10636	MAPT	P45983	MAPK8	S232	D225E	225	Missense	distal	-7	no	7.907	7.898	EPSD	COSMIC	2.638	Down-regulation
CMGC_MAPK_JNK_MAPK8_ST	P10636	MAPT	P45983	MAPK8	S232	S227G	227	Missense	distal	-5	no	7.907	8.283	EPSD	COSMIC	2.638	Up-regulation
CMGC_MAPK_JNK_MAPK8_ST	P10636	MAPT	P45983	MAPK8	S232	S235L	235	Missense	distal	3	no	7.907	8.134	EPSD	COSMIC	2.638	Up-regulation
CMGC_MAPK_JNK_MAPK8_ST	P10636	MAPT	P45983	MAPK8	S238	A237T	237	Missense	proximal	-1	no	7.548	7.547	EPSD	COSMIC	2.638	Down-regulation
CMGC_MAPK_JNK_MAPK8_ST	P10636	MAPT	P45983	MAPK8	S238	A240S	240	Missense	proximal	2	no	7.548	7.524	EPSD	COSMIC	2.638	Down-regulation
CMGC_MAPK_JNK_MAPK8_ST	P10636	MAPT	P45983	MAPK8	S238	D242N	242	Missense	distal	4	no	7.548	7.302	EPSD	COSMIC	2.638	Down-regulation
CMGC_MAPK_JNK_MAPK8_ST	P10636	MAPT	P45983	MAPK8	S238	R244W	244	Missense	distal	6	no	7.548	7.538	EPSD	COSMIC	2.638	Down-regulation
CMGC_MAPK_JNK_MAPK8_ST	P10636	MAPT	P45983	MAPK8	S238	S238P	238	Missense	central	0	yes	7.548	0.000	EPSD	COSMIC	2.638	Loss
CMGC_MAPK_JNK_MAPK8_ST	P10636	MAPT	P45983	MAPK8	S238	P233S	233	Missense	distal	-5	no	7.548	7.436	EPSD	COSMIC	2.638	Down-regulation
CMGC_MAPK_JNK_MAPK8_ST	P10636	MAPT	P45983	MAPK8	S238	S238F	238	Missense	central	0	yes	7.548	0.000	EPSD	COSMIC	2.638	Loss
CMGC_MAPK_JNK_MAPK8_ST	P10636	MAPT	P45983	MAPK8	S238	G243D	243	Missense	distal	5	no	7.548	7.526	EPSD	COSMIC	2.638	Down-regulation
CMGC_MAPK_JNK_MAPK8_ST	P10636	MAPT	P45983	MAPK8	S238	S235L	235	Missense	distal	-3	no	7.548	7.207	EPSD	COSMIC	2.638	Down-regulation
CMGC_MAPK_JNK_MAPK8_ST	P10636	MAPT	P45983	MAPK8	S400	R398C	398	Missense	proximal	-2	no	3.493	3.507	EPSD	COSMIC	2.638	Up-regulation
CMGC_MAPK_JNK_MAPK8_ST	P10636	MAPT	P45983	MAPK8	S400	S396F	396	Missense	distal	-4	no	3.493	2.555	EPSD	COSMIC	2.638	Loss
CMGC_MAPK_JNK_MAPK8_ST	P10636	MAPT	P45983	MAPK8	S411	L410F	410	Missense	proximal	-1	no	7.541	7.540	EPSD	COSMIC	2.638	Down-regulation
CMGC_MAPK_JNK_MAPK8_ST	P10636	MAPT	P45983	MAPK8	S411	P412S	412	Missense	proximal	1	no	7.541	-0.188	EPSD	COSMIC	2.638	Loss
CMGC_MAPK_JNK_MAPK8_ST	P10636	MAPT	P45983	MAPK8	T416	L410F	410	Missense	distal	-6	no	8.962	8.963	EPSD	COSMIC	2.638	Up-regulation
CMGC_MAPK_JNK_MAPK8_ST	P10636	MAPT	P45983	MAPK8	T416	P412S	412	Missense	distal	-4	no	8.962	9.627	EPSD	COSMIC	2.638	Up-regulation
CMGC_MAPK_JNK_MAPK8_ST	P10636	MAPT	P45983	MAPK8	S438	S443Y	443	Missense	distal	5	no	9.810	9.918	EPSD	COSMIC	2.638	Up-regulation
CMGC_MAPK_JNK_MAPK8_ST	P10636	MAPT	P45983	MAPK8	S447	S443Y	443	Missense	distal	-4	no	3.231	1.998	EPSD	COSMIC	2.638	Loss
CMGC_MAPK_JNK_MAPK8_ST	P10636	MAPT	P45983	MAPK8	S447	S447P	447	Missense	central	0	yes	3.231	0.000	EPSD	COSMIC	2.638	Loss
CMGC_MAPK_JNK_MAPK8_ST	P10636	MAPT	P45983	MAPK8	S447	R448Q	448	Missense	proximal	1	no	3.231	3.258	EPSD	COSMIC	2.638	Up-regulation
CMGC_MAPK_JNK_MAPK8_ST	P10636	MAPT	P45983	MAPK8	T470	T466M	466	Missense	distal	-4	no	7.835	7.132	EPSD	COSMIC;GDSC;CCLE	2.638	Down-regulation
CMGC_MAPK_JNK_MAPK8_ST	P10636	MAPT	P45983	MAPK8	T470	K467T	467	Missense	distal	-3	no	7.835	7.739	EPSD	COSMIC	2.638	Down-regulation
CMGC_MAPK_JNK_MAPK8_ST	P10636	MAPT	P45983	MAPK8	T470	P477L	477	Missense	distal	7	no	7.835	7.875	EPSD	COSMIC	2.638	Up-regulation
CMGC_MAPK_JNK_MAPK8_ST	P10636	MAPT	P45983	MAPK8	T470	P477S	477	Missense	distal	7	no	7.835	7.797	EPSD	COSMIC	2.638	Down-regulation
CMGC_MAPK_JNK_MAPK8_ST	P10636	MAPT	P45983	MAPK8	T492	R487K	487	Missense	distal	-5	no	6.477	5.979	EPSD	COSMIC	2.638	Down-regulation
CMGC_MAPK_JNK_MAPK8_ST	P10636	MAPT	P45983	MAPK8	T492	K491R	491	Missense	proximal	-1	no	6.477	6.445	EPSD	COSMIC	2.638	Down-regulation
CMGC_MAPK_JNK_MAPK8_ST	P10636	MAPT	P45983	MAPK8	T492	R487G	487	Missense	distal	-5	no	6.477	6.450	EPSD	COSMIC	2.638	Down-regulation
CMGC_MAPK_JNK_MAPK8_ST	P10636	MAPT	P45983	MAPK8	T492	A495T	495	Missense	distal	3	no	6.477	6.487	EPSD	COSMIC	2.638	Up-regulation
CMGC_MAPK_JNK_MAPK8_ST	P10636	MAPT	P45983	MAPK8	T492	P493L	493	Missense	proximal	1	no	6.477	-1.095	EPSD	COSMIC	2.638	Loss
CMGC_MAPK_JNK_MAPK8_ST	P10636	MAPT	P45983	MAPK8	T498	K491R	491	Missense	distal	-7	no	7.332	7.349	EPSD	COSMIC	2.638	Up-regulation
CMGC_MAPK_JNK_MAPK8_ST	P10636	MAPT	P45983	MAPK8	T498	A495T	495	Missense	distal	-3	no	7.332	7.278	EPSD	COSMIC	2.638	Down-regulation
CMGC_MAPK_JNK_MAPK8_ST	P10636	MAPT	P45983	MAPK8	T498	P493L	493	Missense	distal	-5	no	7.332	7.692	EPSD	COSMIC	2.638	Up-regulation
CMGC_MAPK_JNK_MAPK8_ST	P10636	MAPT	P45983	MAPK8	S516	G521V	521	Missense	distal	5	no	8.663	8.676	EPSD	COSMIC	2.638	Up-regulation
CMGC_MAPK_JNK_MAPK8_ST	P10636	MAPT	P45983	MAPK8	S516	G518V	518	Missense	proximal	2	no	8.663	8.571	EPSD	COSMIC	2.638	Down-regulation
CMGC_MAPK_JNK_MAPK8_ST	P10636	MAPT	P45983	MAPK8	S516	R511C	511	Missense	distal	-5	no	8.663	8.563	EPSD	COSMIC;CCLE	2.638	Down-regulation
CMGC_MAPK_JNK_MAPK8_ST	P10636	MAPT	P45983	MAPK8	S516	G509V	509	Missense	distal	-7	no	8.663	8.668	EPSD	COSMIC	2.638	Up-regulation
CMGC_MAPK_JNK_MAPK8_ST	P10636	MAPT	P45983	MAPK8	S519	G521V	521	Missense	proximal	2	no	8.616	8.525	EPSD	COSMIC	2.638	Down-regulation
CMGC_MAPK_JNK_MAPK8_ST	P10636	MAPT	P45983	MAPK8	S519	R526H	526	Missense	distal	7	no	8.616	8.605	EPSD	COSMIC	2.638	Down-regulation
CMGC_MAPK_JNK_MAPK8_ST	P10636	MAPT	P45983	MAPK8	S519	G518V	518	Missense	proximal	-1	no	8.616	8.606	EPSD	COSMIC	2.638	Down-regulation
CMGC_MAPK_JNK_MAPK8_ST	P10636	MAPT	P45983	MAPK8	T522	G521V	521	Missense	proximal	-1	no	5.986	5.977	EPSD	COSMIC	2.638	Down-regulation
CMGC_MAPK_JNK_MAPK8_ST	P10636	MAPT	P45983	MAPK8	T522	R526H	526	Missense	distal	4	no	5.986	6.023	EPSD	COSMIC	2.638	Up-regulation
CMGC_MAPK_JNK_MAPK8_ST	P10636	MAPT	P45983	MAPK8	T522	G518V	518	Missense	distal	-4	no	5.986	5.842	EPSD	COSMIC	2.638	Down-regulation
CMGC_MAPK_JNK_MAPK8_ST	P10636	MAPT	P45983	MAPK8	T522	R528S	528	Missense	distal	6	no	5.986	6.046	EPSD	COSMIC	2.638	Up-regulation
CMGC_MAPK_JNK_MAPK8_ST	P10636	MAPT	P45983	MAPK8	T529	R526H	526	Missense	distal	-3	no	8.571	8.608	EPSD	COSMIC	2.638	Up-regulation
CMGC_MAPK_JNK_MAPK8_ST	P10636	MAPT	P45983	MAPK8	T529	R528S	528	Missense	proximal	-1	no	8.571	8.596	EPSD	COSMIC	2.638	Up-regulation
CMGC_MAPK_JNK_MAPK8_ST	P10636	MAPT	P45983	MAPK8	T529	P530S	530	Missense	proximal	1	no	8.571	0.842	EPSD	COSMIC	2.638	Loss
CMGC_MAPK_JNK_MAPK8_ST	P10636	MAPT	P45983	MAPK8	T529	P536H	536	Missense	distal	7	no	8.571	8.585	EPSD	COSMIC	2.638	Up-regulation
CMGC_MAPK_JNK_MAPK8_ST	P10636	MAPT	P45983	MAPK8	T529	P535Q	535	Missense	distal	6	no	8.571	8.581	EPSD	COSMIC	2.638	Up-regulation
CMGC_MAPK_JNK_MAPK8_ST	P10636	MAPT	P45983	MAPK8	T534	R528S	528	Missense	distal	-6	no	8.270	8.115	EPSD	COSMIC	2.638	Down-regulation
CMGC_MAPK_JNK_MAPK8_ST	P10636	MAPT	P45983	MAPK8	T534	P530S	530	Missense	distal	-4	no	8.270	8.935	EPSD	COSMIC	2.638	Up-regulation
CMGC_MAPK_JNK_MAPK8_ST	P10636	MAPT	P45983	MAPK8	T534	P536H	536	Missense	proximal	2	no	8.270	8.272	EPSD	COSMIC	2.638	Up-regulation
CMGC_MAPK_JNK_MAPK8_ST	P10636	MAPT	P45983	MAPK8	T534	P535Q	535	Missense	proximal	1	no	8.270	1.161	EPSD	COSMIC	2.638	Loss
CMGC_MAPK_JNK_MAPK8_ST	P10636	MAPT	P45983	MAPK8	T534	E539Q	539	Missense	distal	5	no	8.270	8.301	EPSD	COSMIC	2.638	Up-regulation
CMGC_MAPK_JNK_MAPK8_ST	P10636	MAPT	P45983	MAPK8	T548	P550S	550	Missense	proximal	2	no	8.519	8.705	EPSD	COSMIC	2.638	Up-regulation
CMGC_MAPK_JNK_MAPK8_ST	P10636	MAPT	P45983	MAPK8	T548	P553R	553	Missense	distal	5	no	8.519	8.508	EPSD	COSMIC	2.638	Down-regulation
CMGC_MAPK_JNK_MAPK8_ST	P10636	MAPT	P45983	MAPK8	T548	P553L	553	Missense	distal	5	no	8.519	8.518	EPSD	COSMIC	2.638	Down-regulation
CMGC_MAPK_JNK_MAPK8_ST	P10636	MAPT	P45983	MAPK8	T548	P549L	549	Missense	proximal	1	no	8.519	0.947	EPSD	COSMIC	2.638	Loss
CMGC_MAPK_JNK_MAPK8_ST	P10636	MAPT	P45983	MAPK8	T548	S555F	555	Missense	distal	7	no	8.519	8.594	EPSD	COSMIC	2.638	Up-regulation
CMGC_MAPK_JNK_MAPK8_ST	P10636	MAPT	P45983	MAPK8	T548	P553Q	553	Missense	distal	5	no	8.519	8.457	EPSD	COSMIC	2.638	Down-regulation
CMGC_MAPK_JNK_MAPK8_ST	P10636	MAPT	P45983	MAPK8	S552	P550S	550	Missense	proximal	-2	no	7.655	7.550	EPSD	COSMIC	2.638	Down-regulation
CMGC_MAPK_JNK_MAPK8_ST	P10636	MAPT	P45983	MAPK8	S552	R559C	559	Missense	distal	7	no	7.655	7.644	EPSD	COSMIC	2.638	Down-regulation
CMGC_MAPK_JNK_MAPK8_ST	P10636	MAPT	P45983	MAPK8	S552	P553R	553	Missense	proximal	1	no	7.655	0.519	EPSD	COSMIC	2.638	Loss
CMGC_MAPK_JNK_MAPK8_ST	P10636	MAPT	P45983	MAPK8	S552	P553L	553	Missense	proximal	1	no	7.655	0.083	EPSD	COSMIC	2.638	Loss
CMGC_MAPK_JNK_MAPK8_ST	P10636	MAPT	P45983	MAPK8	S552	P549L	549	Missense	distal	-3	no	7.655	7.476	EPSD	COSMIC	2.638	Down-regulation
CMGC_MAPK_JNK_MAPK8_ST	P10636	MAPT	P45983	MAPK8	S552	S555F	555	Missense	distal	3	no	7.655	7.875	EPSD	COSMIC	2.638	Up-regulation
CMGC_MAPK_JNK_MAPK8_ST	P10636	MAPT	P45983	MAPK8	S552	P553Q	553	Missense	proximal	1	no	7.655	0.546	EPSD	COSMIC	2.638	Loss
CMGC_MAPK_JNK_MAPK8_ST	P10636	MAPT	P45983	MAPK8	S555	P550S	550	Missense	distal	-5	no	3.344	3.232	EPSD	COSMIC	2.638	Down-regulation
CMGC_MAPK_JNK_MAPK8_ST	P10636	MAPT	P45983	MAPK8	S555	R559C	559	Missense	distal	4	no	3.344	3.378	EPSD	COSMIC	2.638	Up-regulation
CMGC_MAPK_JNK_MAPK8_ST	P10636	MAPT	P45983	MAPK8	S555	P553R	553	Missense	proximal	-2	no	3.344	3.161	EPSD	COSMIC	2.638	Down-regulation
CMGC_MAPK_JNK_MAPK8_ST	P10636	MAPT	P45983	MAPK8	S555	P553L	553	Missense	proximal	-2	no	3.344	3.151	EPSD	COSMIC	2.638	Down-regulation
CMGC_MAPK_JNK_MAPK8_ST	P10636	MAPT	P45983	MAPK8	S555	P549L	549	Missense	distal	-6	no	3.344	3.435	EPSD	COSMIC	2.638	Up-regulation
CMGC_MAPK_JNK_MAPK8_ST	P10636	MAPT	P45983	MAPK8	S555	S555F	555	Missense	central	0	yes	3.344	0.000	EPSD	COSMIC	2.638	Loss
CMGC_MAPK_JNK_MAPK8_ST	P10636	MAPT	P45983	MAPK8	S555	P553Q	553	Missense	proximal	-2	no	3.344	3.234	EPSD	COSMIC	2.638	Down-regulation
CMGC_MAPK_JNK_MAPK8_ST	P10636	MAPT	P45983	MAPK8	S558	V565M	565	Missense	distal	7	no	3.924	3.907	EPSD	COSMIC	2.638	Down-regulation
CMGC_MAPK_JNK_MAPK8_ST	P10636	MAPT	P45983	MAPK8	S558	R559C	559	Missense	proximal	1	no	3.924	3.481	EPSD	COSMIC	2.638	Down-regulation
CMGC_MAPK_JNK_MAPK8_ST	P10636	MAPT	P45983	MAPK8	S558	P553R	553	Missense	distal	-5	no	3.924	4.216	EPSD	COSMIC	2.638	Up-regulation
CMGC_MAPK_JNK_MAPK8_ST	P10636	MAPT	P45983	MAPK8	S558	P553L	553	Missense	distal	-5	no	3.924	4.284	EPSD	COSMIC	2.638	Up-regulation
CMGC_MAPK_JNK_MAPK8_ST	P10636	MAPT	P45983	MAPK8	S558	S555F	555	Missense	distal	-3	no	3.924	3.550	EPSD	COSMIC	2.638	Down-regulation
CMGC_MAPK_JNK_MAPK8_ST	P10636	MAPT	P45983	MAPK8	S558	P553Q	553	Missense	distal	-5	no	3.924	3.901	EPSD	COSMIC	2.638	Down-regulation
CMGC_MAPK_JNK_MAPK8_ST	P10636	MAPT	P45983	MAPK8	S575	T580N	580	Missense	distal	5	no	2.612	2.674	EPSD	COSMIC	2.638	Gain
CMGC_MAPK_JNK_MAPK8_ST	P10636	MAPT	P45983	MAPK8	T703	R696H	696	Missense	distal	-7	no	2.783	2.781	EPSD	COSMIC	2.638	Down-regulation
CMGC_MAPK_JNK_MAPK8_ST	P10636	MAPT	P45983	MAPK8	T703	E708D	708	Missense	distal	5	no	2.783	2.841	EPSD	COSMIC	2.638	Up-regulation
CMGC_MAPK_JNK_MAPK8_ST	P10636	MAPT	P45983	MAPK8	T703	G706R	706	Missense	distal	3	no	2.783	2.776	EPSD	COSMIC	2.638	Down-regulation
CMGC_MAPK_JNK_MAPK8_ST	P10636	MAPT	P45983	MAPK8	T703	V710M	710	Missense	distal	7	no	2.783	2.766	EPSD	COSMIC	2.638	Down-regulation
CMGC_MAPK_JNK_MAPK8_ST	P10636	MAPT	P45983	MAPK8	T703	E708K	708	Missense	distal	5	no	2.783	2.775	EPSD	COSMIC	2.638	Down-regulation
CMGC_MAPK_JNK_MAPK8_ST	P10636	MAPT	P45983	MAPK8	T703	R696C	696	Missense	distal	-7	no	2.783	2.781	EPSD	COSMIC	2.638	Down-regulation
CMGC_MAPK_JNK_MAPK8_ST	P10636	MAPT	P45983	MAPK8	T703	V710A	710	Missense	distal	7	no	2.783	2.704	EPSD	COSMIC	2.638	Down-regulation
CMGC_MAPK_JNK_MAPK8_ST	P10636	MAPT	P45983	MAPK8	T703	T703I	703	Missense	central	0	yes	2.783	0.000	EPSD	COSMIC	2.638	Loss
CMGC_MAPK_JNK_MAPK8_ST	P10636	MAPT	P45983	MAPK8	S713	E708D	708	Missense	distal	-5	no	9.699	9.942	EPSD	COSMIC	2.638	Up-regulation
CMGC_MAPK_JNK_MAPK8_ST	P10636	MAPT	P45983	MAPK8	S713	G706R	706	Missense	distal	-7	no	9.699	9.700	EPSD	COSMIC	2.638	Up-regulation
CMGC_MAPK_JNK_MAPK8_ST	P10636	MAPT	P45983	MAPK8	S713	V710M	710	Missense	distal	-3	no	9.699	9.768	EPSD	COSMIC	2.638	Up-regulation
CMGC_MAPK_JNK_MAPK8_ST	P10636	MAPT	P45983	MAPK8	S713	E708K	708	Missense	distal	-5	no	9.699	9.623	EPSD	COSMIC	2.638	Down-regulation
CMGC_MAPK_JNK_MAPK8_ST	P10636	MAPT	P45983	MAPK8	S713	V710A	710	Missense	distal	-3	no	9.699	10.129	EPSD	COSMIC	2.638	Up-regulation
CMGC_MAPK_JNK_MAPK8_ST	P10636	MAPT	P45983	MAPK8	S721	R723W	723	Missense	proximal	2	no	8.703	8.631	EPSD	COSMIC	2.638	Down-regulation
CMGC_MAPK_JNK_MAPK8_ST	P10636	MAPT	P45983	MAPK8	S721	V728M	728	Missense	distal	7	no	8.703	8.686	EPSD	COSMIC	2.638	Down-regulation
CMGC_MAPK_JNK_MAPK8_ST	P10636	MAPT	P45983	MAPK8	S721	V728A	728	Missense	distal	7	no	8.703	8.624	EPSD	COSMIC	2.638	Down-regulation
CMGC_MAPK_JNK_MAPK8_ST	P10636	MAPT	P45983	MAPK8	S733	G732S	732	Missense	proximal	-1	no	3.219	3.243	EPSD	COSMIC	2.638	Up-regulation
CMGC_MAPK_JNK_MAPK8_ST	P10636	MAPT	P45983	MAPK8	S733	D735N	735	Missense	proximal	2	no	3.219	3.093	EPSD	COSMIC	2.638	Down-regulation
CMGC_MAPK_JNK_MAPK8_ST	P10636	MAPT	P45983	MAPK8	S733	G732C	732	Missense	proximal	-1	no	3.219	3.224	EPSD	COSMIC	2.638	Up-regulation
CMGC_MAPK_JNK_MAPK8_ST	P10636	MAPT	P45983	MAPK8	S733	V728M	728	Missense	distal	-5	no	3.219	3.135	EPSD	COSMIC	2.638	Down-regulation
CMGC_MAPK_JNK_MAPK8_ST	P10636	MAPT	P45983	MAPK8	S733	V728A	728	Missense	distal	-5	no	3.219	2.678	EPSD	COSMIC	2.638	Down-regulation
CMGC_MAPK_JNK_MAPK8_ST	P10636	MAPT	P45983	MAPK8	S739	G732S	732	Missense	distal	-7	no	7.702	7.688	EPSD	COSMIC	2.638	Down-regulation
CMGC_MAPK_JNK_MAPK8_ST	P10636	MAPT	P45983	MAPK8	S739	D735N	735	Missense	distal	-4	no	7.702	7.395	EPSD	COSMIC	2.638	Down-regulation
CMGC_MAPK_JNK_MAPK8_ST	P10636	MAPT	P45983	MAPK8	S739	G732C	732	Missense	distal	-7	no	7.702	7.700	EPSD	COSMIC	2.638	Down-regulation
CMGC_MAPK_JNK_MAPK8_ST	P10636	MAPT	P45983	MAPK8	S739	T744M	744	Missense	distal	5	no	7.702	7.768	EPSD	COSMIC	2.638	Up-regulation
CMGC_MAPK_JNK_MAPK8_ST	P10636	MAPT	P45983	MAPK8	S739	A743T	743	Missense	distal	4	no	7.702	7.654	EPSD	COSMIC	2.638	Down-regulation
CMGC_MAPK_JNK_MAPK8_ST	P17275	JUNB	P45983	MAPK8	S74	G73C	73	Missense	proximal	-1	no	2.706	2.712	EPSD	COSMIC	2.638	Up-regulation
CMGC_MAPK_JNK_MAPK8_ST	P17275	JUNB	P45983	MAPK8	S74	D75N	75	Missense	proximal	1	no	2.706	0.647	EPSD	COSMIC	2.638	Loss
CMGC_MAPK_JNK_MAPK8_ST	P17275	JUNB	P45983	MAPK8	S74	S74W	74	Missense	central	0	yes	2.706	0.000	EPSD	COSMIC	2.638	Loss
CMGC_MAPK_JNK_MAPK8_ST	P17275	JUNB	P45983	MAPK8	T102	P103H	103	Missense	proximal	1	no	8.898	0.983	PhosphoSitePlus;EPSD	COSMIC;GDSC;CCLE	2.638	Loss
CMGC_MAPK_JNK_MAPK8_ST	P17275	JUNB	P45983	MAPK8	T102	N96T	96	Missense	distal	-6	no	8.898	8.748	PhosphoSitePlus;EPSD	COSMIC	2.638	Down-regulation
CMGC_MAPK_JNK_MAPK8_ST	P17275	JUNB	P45983	MAPK8	T104	P103H	103	Missense	proximal	-1	no	8.622	8.612	EPSD;PhosphoSitePlus	COSMIC;GDSC;CCLE	2.638	Down-regulation
CMGC_MAPK_JNK_MAPK8_ST	P17275	JUNB	P45983	MAPK8	T255	R250L	250	Missense	distal	-5	no	7.948	8.016	EPSD	COSMIC	2.638	Up-regulation
CMGC_MAPK_JNK_MAPK8_ST	Q9NRA8	EIF4ENIF1	P45983	MAPK8	S78	A73D	73	Missense	distal	-5	no	7.112	7.353	EPSD	COSMIC	2.638	Up-regulation
CMGC_MAPK_JNK_MAPK8_ST	Q9NRA8	EIF4ENIF1	P45983	MAPK8	S78	V80A	80	Missense	proximal	2	no	7.112	7.430	EPSD	COSMIC	2.638	Up-regulation
CMGC_MAPK_JNK_MAPK8_ST	Q9NRA8	EIF4ENIF1	P45983	MAPK8	S138	R135C	135	Missense	distal	-3	no	6.232	6.281	EPSD	COSMIC	2.638	Up-regulation
CMGC_MAPK_JNK_MAPK8_ST	Q9NRA8	EIF4ENIF1	P45983	MAPK8	S301	A295D	295	Missense	distal	-6	no	9.158	9.248	EPSD;PhosphoSitePlus	COSMIC	2.638	Up-regulation
CMGC_MAPK_JNK_MAPK8_ST	Q9NRA8	EIF4ENIF1	P45983	MAPK8	S301	P302T	302	Missense	proximal	1	no	9.158	2.172	EPSD;PhosphoSitePlus	COSMIC	2.638	Loss
CMGC_MAPK_JNK_MAPK8_ST	Q9NRA8	EIF4ENIF1	P45983	MAPK8	S301	P298H	298	Missense	distal	-3	no	9.158	9.053	EPSD;PhosphoSitePlus	COSMIC	2.638	Down-regulation
CMGC_MAPK_JNK_MAPK8_ST	Q9NRA8	EIF4ENIF1	P45983	MAPK8	S321	M322I	322	Missense	proximal	1	no	1.072	3.058	EPSD	COSMIC	2.638	Gain
CMGC_MAPK_JNK_MAPK8_ST	Q9NRA8	EIF4ENIF1	P45983	MAPK8	S333	W340R	340	Missense	distal	7	no	3.353	3.340	EPSD	COSMIC	2.638	Down-regulation
CMGC_MAPK_JNK_MAPK8_ST	Q9NRA8	EIF4ENIF1	P45983	MAPK8	T357	E363Q	363	Missense	distal	6	no	7.279	7.264	EPSD	COSMIC	2.638	Down-regulation
CMGC_MAPK_JNK_MAPK8_ST	Q9NRA8	EIF4ENIF1	P45983	MAPK8	S374	P375L	375	Missense	proximal	1	no	6.958	-0.615	EPSD;PhosphoSitePlus	COSMIC	2.638	Loss
CMGC_MAPK_JNK_MAPK8_ST	Q9NRA8	EIF4ENIF1	P45983	MAPK8	T455	N453Y	453	Missense	proximal	-2	no	7.596	7.585	EPSD	COSMIC	2.638	Down-regulation
CMGC_MAPK_JNK_MAPK8_ST	Q9NRA8	EIF4ENIF1	P45983	MAPK8	S564	S568L	568	Missense	distal	4	no	9.497	9.065	EPSD	COSMIC	2.638	Down-regulation
CMGC_MAPK_JNK_MAPK8_ST	Q9NRA8	EIF4ENIF1	P45983	MAPK8	S564	S564A	564	Missense	central	0	yes	9.497	0.000	EPSD	COSMIC	2.638	Loss
CMGC_MAPK_JNK_MAPK8_ST	Q9NRA8	EIF4ENIF1	P45983	MAPK8	S564	L558P	558	Missense	distal	-6	no	9.497	9.406	EPSD	COSMIC	2.638	Down-regulation
CMGC_MAPK_JNK_MAPK8_ST	Q9NRA8	EIF4ENIF1	P45983	MAPK8	S587	P588S	588	Missense	proximal	1	no	8.615	0.886	EPSD;PhosphoSitePlus	COSMIC	2.638	Loss
CMGC_MAPK_JNK_MAPK8_ST	Q9NRA8	EIF4ENIF1	P45983	MAPK8	T592	P588S	588	Missense	distal	-4	no	6.699	7.364	EPSD	COSMIC	2.638	Up-regulation
CMGC_MAPK_JNK_MAPK8_ST	Q9NRA8	EIF4ENIF1	P45983	MAPK8	S611	R607C	607	Missense	distal	-4	no	8.914	8.947	EPSD	COSMIC	2.638	Up-regulation
CMGC_MAPK_JNK_MAPK8_ST	Q9NRA8	EIF4ENIF1	P45983	MAPK8	S611	P612S	612	Missense	proximal	1	no	8.914	1.185	EPSD	COSMIC	2.638	Loss
CMGC_MAPK_JNK_MAPK8_ST	Q9NRA8	EIF4ENIF1	P45983	MAPK8	S670	Q664K	664	Missense	distal	-6	no	5.267	5.202	EPSD	COSMIC	2.638	Down-regulation
CMGC_MAPK_JNK_MAPK8_ST	Q9NRA8	EIF4ENIF1	P45983	MAPK8	S670	A672S	672	Missense	proximal	2	no	5.267	5.243	EPSD	COSMIC	2.638	Down-regulation
CMGC_MAPK_JNK_MAPK8_ST	Q9NRA8	EIF4ENIF1	P45983	MAPK8	S670	R666Q	666	Missense	distal	-4	no	5.267	5.787	EPSD	COSMIC	2.638	Up-regulation
CMGC_MAPK_JNK_MAPK8_ST	Q9NRA8	EIF4ENIF1	P45983	MAPK8	S670	G677D	677	Missense	distal	7	no	5.267	5.242	EPSD	COSMIC	2.638	Down-regulation
CMGC_MAPK_JNK_MAPK8_ST	Q9NRA8	EIF4ENIF1	P45983	MAPK8	S670	P671R	671	Missense	proximal	1	no	5.267	-1.870	EPSD	COSMIC	2.638	Loss
CMGC_MAPK_JNK_MAPK8_ST	Q9NRA8	EIF4ENIF1	P45983	MAPK8	S681	S679Y	679	Missense	proximal	-2	no	8.891	8.762	EPSD	COSMIC	2.638	Down-regulation
CMGC_MAPK_JNK_MAPK8_ST	Q9NRA8	EIF4ENIF1	P45983	MAPK8	S681	G677D	677	Missense	distal	-4	no	8.891	9.213	EPSD	COSMIC	2.638	Up-regulation
CMGC_MAPK_JNK_MAPK8_ST	Q9NRA8	EIF4ENIF1	P45983	MAPK8	S693	S700L	700	Missense	distal	7	no	8.039	8.117	EPSD;PhosphoSitePlus	COSMIC	2.638	Up-regulation
CMGC_MAPK_JNK_MAPK8_ST	Q9NRA8	EIF4ENIF1	P45983	MAPK8	T697	S700L	700	Missense	distal	3	no	6.708	6.935	EPSD	COSMIC	2.638	Up-regulation
CMGC_MAPK_JNK_MAPK8_ST	Q9NRA8	EIF4ENIF1	P45983	MAPK8	S746	R749L	749	Missense	distal	3	no	3.118	3.163	EPSD	COSMIC	2.638	Up-regulation
CMGC_MAPK_JNK_MAPK8_ST	Q9NRA8	EIF4ENIF1	P45983	MAPK8	S746	S742L	742	Missense	distal	-4	no	3.118	2.126	EPSD	COSMIC	2.638	Loss
CMGC_MAPK_JNK_MAPK8_ST	Q9NRA8	EIF4ENIF1	P45983	MAPK8	S752	R749L	749	Missense	distal	-3	no	9.877	9.840	EPSD;PhosphoSitePlus	COSMIC	2.638	Down-regulation
CMGC_MAPK_JNK_MAPK8_ST	Q9NRA8	EIF4ENIF1	P45983	MAPK8	S760	Q763H	763	Missense	distal	3	no	3.135	3.242	EPSD	COSMIC	2.638	Up-regulation
CMGC_MAPK_JNK_MAPK8_ST	Q9NRA8	EIF4ENIF1	P45983	MAPK8	T769	Q763H	763	Missense	distal	-6	no	7.541	7.621	EPSD	COSMIC	2.638	Up-regulation
CMGC_MAPK_JNK_MAPK8_ST	Q9NRA8	EIF4ENIF1	P45983	MAPK8	T792	T794P	794	Missense	proximal	2	no	8.521	8.333	EPSD	COSMIC	2.638	Down-regulation
CMGC_MAPK_JNK_MAPK8_ST	Q9NRA8	EIF4ENIF1	P45983	MAPK8	T792	P793S	793	Missense	proximal	1	no	8.521	0.793	EPSD	COSMIC	2.638	Loss
CMGC_MAPK_JNK_MAPK8_ST	Q9NRA8	EIF4ENIF1	P45983	MAPK8	T792	V799I	799	Missense	distal	7	no	8.521	8.477	EPSD	COSMIC;GDSC	2.638	Down-regulation
CMGC_MAPK_JNK_MAPK8_ST	Q9NRA8	EIF4ENIF1	P45983	MAPK8	T792	P798S	798	Missense	distal	6	no	8.521	8.546	EPSD	COSMIC	2.638	Up-regulation
CMGC_MAPK_JNK_MAPK8_ST	Q9NRA8	EIF4ENIF1	P45983	MAPK8	S797	T794P	794	Missense	distal	-3	no	8.896	8.752	EPSD	COSMIC	2.638	Down-regulation
CMGC_MAPK_JNK_MAPK8_ST	Q9NRA8	EIF4ENIF1	P45983	MAPK8	S797	P793S	793	Missense	distal	-4	no	8.896	9.561	EPSD	COSMIC	2.638	Up-regulation
CMGC_MAPK_JNK_MAPK8_ST	Q9NRA8	EIF4ENIF1	P45983	MAPK8	S797	V799I	799	Missense	proximal	2	no	8.896	9.067	EPSD	COSMIC;GDSC	2.638	Up-regulation
CMGC_MAPK_JNK_MAPK8_ST	Q9NRA8	EIF4ENIF1	P45983	MAPK8	S797	P798S	798	Missense	proximal	1	no	8.896	1.168	EPSD	COSMIC	2.638	Loss
CMGC_MAPK_JNK_MAPK8_ST	Q9NRA8	EIF4ENIF1	P45983	MAPK8	T802	L805F	805	Missense	distal	3	no	6.224	6.216	EPSD	COSMIC	2.638	Down-regulation
CMGC_MAPK_JNK_MAPK8_ST	Q9NRA8	EIF4ENIF1	P45983	MAPK8	T802	V799I	799	Missense	distal	-3	no	6.224	6.459	EPSD	COSMIC;GDSC	2.638	Up-regulation
CMGC_MAPK_JNK_MAPK8_ST	Q9NRA8	EIF4ENIF1	P45983	MAPK8	T802	P798S	798	Missense	distal	-4	no	6.224	6.889	EPSD	COSMIC	2.638	Up-regulation
CMGC_MAPK_JNK_MAPK8_ST	Q9NRA8	EIF4ENIF1	P45983	MAPK8	T891	R888C	888	Missense	distal	-3	no	7.291	7.340	EPSD	COSMIC	2.638	Up-regulation
CMGC_MAPK_JNK_MAPK8_ST	Q9NRA8	EIF4ENIF1	P45983	MAPK8	T924	R931L	931	Missense	distal	7	no	8.601	8.616	EPSD	COSMIC	2.638	Up-regulation
CMGC_MAPK_JNK_MAPK8_ST	Q9NRA8	EIF4ENIF1	P45983	MAPK8	T924	V919D	919	Missense	distal	-5	no	8.601	8.300	EPSD	COSMIC	2.638	Down-regulation
CMGC_MAPK_JNK_MAPK8_ST	Q9NRA8	EIF4ENIF1	P45983	MAPK8	S951	G954V	954	Missense	distal	3	no	7.297	7.353	EPSD	COSMIC	2.638	Up-regulation
CMGC_MAPK_JNK_MAPK8_ST	Q9NRA8	EIF4ENIF1	P45983	MAPK8	S951	R944H	944	Missense	distal	-7	no	7.297	7.295	EPSD	COSMIC	2.638	Down-regulation
CMGC_MAPK_JNK_MAPK8_ST	Q05639	EEF1A2	P45983	MAPK8	S205	G198S	198	Missense	distal	-7	no	7.665	7.652	EPSD;PhosphoSitePlus	COSMIC	2.638	Down-regulation
CMGC_MAPK_JNK_MAPK8_ST	Q05639	EEF1A2	P45983	MAPK8	S358	I361T	361	Missense	distal	3	no	8.216	8.120	PhosphoSitePlus;EPSD	COSMIC	2.638	Down-regulation
CMGC_MAPK_JNK_MAPK8_ST	Q05639	EEF1A2	P45983	MAPK8	S358	V360I	360	Missense	proximal	2	no	8.216	8.387	PhosphoSitePlus;EPSD	COSMIC	2.638	Up-regulation
CMGC_MAPK_JNK_MAPK8_ST	Q9H211	CDT1	P45983	MAPK8	S45	T44P	44	Missense	proximal	-1	no	2.856	2.845	EPSD	COSMIC	2.638	Down-regulation
CMGC_MAPK_JNK_MAPK8_ST	Q9H211	CDT1	P45983	MAPK8	S79	T82I	82	Missense	distal	3	no	9.355	9.451	EPSD	COSMIC	2.638	Up-regulation
CMGC_MAPK_JNK_MAPK8_ST	Q9H211	CDT1	P45983	MAPK8	T82	P89T	89	Missense	distal	7	no	8.851	8.820	EPSD	COSMIC	2.638	Down-regulation
CMGC_MAPK_JNK_MAPK8_ST	Q9H211	CDT1	P45983	MAPK8	T82	T82I	82	Missense	central	0	yes	8.851	0.000	EPSD	COSMIC	2.638	Loss
CMGC_MAPK_JNK_MAPK8_ST	Q9H211	CDT1	P45983	MAPK8	S93	P89T	89	Missense	distal	-4	no	7.852	8.303	EPSD	COSMIC	2.638	Up-regulation
CMGC_MAPK_JNK_MAPK8_ST	Q9H211	CDT1	P45983	MAPK8	S391	A388V	388	Missense	distal	-3	no	7.295	6.865	EPSD;PhosphoSitePlus	COSMIC	2.638	Down-regulation
CMGC_MAPK_JNK_MAPK8_ST	Q9H211	CDT1	P45983	MAPK8	S391	A388G	388	Missense	distal	-3	no	7.295	6.978	EPSD;PhosphoSitePlus	COSMIC	2.638	Down-regulation
CMGC_MAPK_JNK_MAPK8_ST	Q9H211	CDT1	P45983	MAPK8	S394	A388V	388	Missense	distal	-6	no	9.045	9.246	EPSD	COSMIC	2.638	Up-regulation
CMGC_MAPK_JNK_MAPK8_ST	Q9H211	CDT1	P45983	MAPK8	S394	P400S	400	Missense	distal	6	no	9.045	9.069	EPSD	COSMIC	2.638	Up-regulation
CMGC_MAPK_JNK_MAPK8_ST	Q9H211	CDT1	P45983	MAPK8	S394	A388G	388	Missense	distal	-6	no	9.045	9.193	EPSD	COSMIC	2.638	Up-regulation
CMGC_MAPK_JNK_MAPK8_ST	Q9H211	CDT1	P45983	MAPK8	T402	P408H	408	Missense	distal	6	no	8.894	8.871	EPSD;PhosphoSitePlus	COSMIC	2.638	Down-regulation
CMGC_MAPK_JNK_MAPK8_ST	Q9H211	CDT1	P45983	MAPK8	T402	P400S	400	Missense	proximal	-2	no	8.894	8.789	EPSD;PhosphoSitePlus	COSMIC	2.638	Down-regulation
CMGC_MAPK_JNK_MAPK8_ST	Q9H211	CDT1	P45983	MAPK8	T402	P403T	403	Missense	proximal	1	no	8.894	1.908	EPSD;PhosphoSitePlus	COSMIC	2.638	Loss
CMGC_MAPK_JNK_MAPK8_ST	Q9H211	CDT1	P45983	MAPK8	T402	P407S	407	Missense	distal	5	no	8.894	8.811	EPSD;PhosphoSitePlus	COSMIC	2.638	Down-regulation
CMGC_MAPK_JNK_MAPK8_ST	Q9H211	CDT1	P45983	MAPK8	T402	T402I	402	Missense	central	0	yes	8.894	0.000	EPSD;PhosphoSitePlus	COSMIC	2.638	Loss
CMGC_MAPK_JNK_MAPK8_ST	Q9H211	CDT1	P45983	MAPK8	T406	P408H	408	Missense	proximal	2	no	7.981	7.983	EPSD;PhosphoSitePlus	COSMIC	2.638	Up-regulation
CMGC_MAPK_JNK_MAPK8_ST	Q9H211	CDT1	P45983	MAPK8	T406	P400S	400	Missense	distal	-6	no	7.981	7.892	EPSD;PhosphoSitePlus	COSMIC	2.638	Down-regulation
CMGC_MAPK_JNK_MAPK8_ST	Q9H211	CDT1	P45983	MAPK8	T406	P403T	403	Missense	distal	-3	no	7.981	8.125	EPSD;PhosphoSitePlus	COSMIC	2.638	Up-regulation
CMGC_MAPK_JNK_MAPK8_ST	Q9H211	CDT1	P45983	MAPK8	T406	P407S	407	Missense	proximal	1	no	7.981	0.253	EPSD;PhosphoSitePlus	COSMIC	2.638	Loss
CMGC_MAPK_JNK_MAPK8_ST	Q9H211	CDT1	P45983	MAPK8	T406	T402I	402	Missense	distal	-4	no	7.981	7.555	EPSD;PhosphoSitePlus	COSMIC	2.638	Down-regulation
CMGC_MAPK_JNK_MAPK8_ST	Q9H211	CDT1	P45983	MAPK8	S411	P408H	408	Missense	distal	-3	no	8.546	8.440	EPSD;PhosphoSitePlus	COSMIC	2.638	Down-regulation
CMGC_MAPK_JNK_MAPK8_ST	Q9H211	CDT1	P45983	MAPK8	S411	P407S	407	Missense	distal	-4	no	8.546	9.210	EPSD;PhosphoSitePlus	COSMIC	2.638	Up-regulation
CMGC_MAPK_JNK_MAPK8_ST	Q9H211	CDT1	P45983	MAPK8	S491	H498Y	498	Missense	distal	7	no	8.680	8.721	EPSD;PhosphoSitePlus	COSMIC	2.638	Up-regulation
CMGC_MAPK_JNK_MAPK8_ST	Q9H211	CDT1	P45983	MAPK8	S491	S485N	485	Missense	distal	-6	no	8.680	8.856	EPSD;PhosphoSitePlus	COSMIC	2.638	Up-regulation
CMGC_MAPK_JNK_MAPK8_ST	P15336	ATF2	P45983	MAPK8	T69	T73A	73	Missense	distal	4	no	8.052	8.101	PhosphoSitePlus;EPSD	COSMIC	2.638	Up-regulation
CMGC_MAPK_JNK_MAPK8_ST	P15336	ATF2	P45983	MAPK8	T69	F75L	75	Missense	distal	6	no	8.052	8.050	PhosphoSitePlus;EPSD	COSMIC	2.638	Down-regulation
CMGC_MAPK_JNK_MAPK8_ST	P15336	ATF2	P45983	MAPK8	T69	R74T	74	Missense	distal	5	no	8.052	7.987	PhosphoSitePlus;EPSD	COSMIC	2.638	Down-regulation
CMGC_MAPK_JNK_MAPK8_ST	P15336	ATF2	P45983	MAPK8	T69	I64V	64	Missense	distal	-5	no	8.052	8.373	PhosphoSitePlus;EPSD	COSMIC	2.638	Up-regulation
CMGC_MAPK_JNK_MAPK8_ST	P15336	ATF2	P45983	MAPK8	T69	D67E	67	Missense	proximal	-2	no	8.052	8.106	PhosphoSitePlus;EPSD	COSMIC	2.638	Up-regulation
CMGC_MAPK_JNK_MAPK8_ST	P15336	ATF2	P45983	MAPK8	T71	T73A	73	Missense	proximal	2	no	8.758	8.779	EPSD;PhosphoSitePlus	COSMIC	2.638	Up-regulation
CMGC_MAPK_JNK_MAPK8_ST	P15336	ATF2	P45983	MAPK8	T71	F75L	75	Missense	distal	4	no	8.758	8.784	EPSD;PhosphoSitePlus	COSMIC	2.638	Up-regulation
CMGC_MAPK_JNK_MAPK8_ST	P15336	ATF2	P45983	MAPK8	T71	R74T	74	Missense	distal	3	no	8.758	8.603	EPSD;PhosphoSitePlus	COSMIC	2.638	Down-regulation
CMGC_MAPK_JNK_MAPK8_ST	P15336	ATF2	P45983	MAPK8	T71	I64V	64	Missense	distal	-7	no	8.758	8.767	EPSD;PhosphoSitePlus	COSMIC	2.638	Up-regulation
CMGC_MAPK_JNK_MAPK8_ST	P15336	ATF2	P45983	MAPK8	T71	D67E	67	Missense	distal	-4	no	8.758	9.181	EPSD;PhosphoSitePlus	COSMIC	2.638	Up-regulation
CMGC_MAPK_JNK_MAPK8_ST	P15336	ATF2	P45983	MAPK8	S90	P91S	91	Missense	proximal	1	no	8.111	0.382	EPSD;PhosphoSitePlus	COSMIC	2.638	Loss
CMGC_MAPK_JNK_MAPK8_ST	P15336	ATF2	P45983	MAPK8	S90	A89V	89	Missense	proximal	-1	no	8.111	8.075	EPSD;PhosphoSitePlus	COSMIC	2.638	Down-regulation
CMGC_MAPK_JNK_MAPK8_ST	P15336	ATF2	P45983	MAPK8	S90	P91L	91	Missense	proximal	1	no	8.111	0.538	EPSD;PhosphoSitePlus	COSMIC	2.638	Loss
CMGC_MAPK_JNK_MAPK8_ST	P15336	ATF2	P45983	MAPK8	S90	G83C	83	Missense	distal	-7	no	8.111	8.109	EPSD;PhosphoSitePlus	COSMIC	2.638	Down-regulation
CMGC_MAPK_JNK_MAPK8_ST	P15336	ATF2	P45983	MAPK8	S112	M107I	107	Missense	distal	-5	no	6.996	6.759	EPSD	COSMIC;GDSC;CCLE	2.638	Down-regulation
CMGC_MAPK_JNK_MAPK8_ST	P15336	ATF2	P45983	MAPK8	S112	K105T	105	Missense	distal	-7	no	6.996	7.002	EPSD	COSMIC;GDSC;CCLE	2.638	Up-regulation
CMGC_MAPK_JNK_MAPK8_ST	P15336	ATF2	P45983	MAPK8	S112	K106R	106	Missense	distal	-6	no	6.996	7.163	EPSD	COSMIC	2.638	Up-regulation
CMGC_MAPK_JNK_MAPK8_ST	P15336	ATF2	P45983	MAPK8	S112	D110E	110	Missense	proximal	-2	no	6.996	7.050	EPSD	COSMIC	2.638	Up-regulation
CMGC_MAPK_JNK_MAPK8_ST	P15336	ATF2	P45983	MAPK8	T116	D110E	110	Missense	distal	-6	no	8.713	8.613	EPSD	COSMIC	2.638	Down-regulation
CMGC_MAPK_JNK_MAPK8_ST	P15336	ATF2	P45983	MAPK8	S136	P141T	141	Missense	distal	5	no	8.636	8.559	EPSD	COSMIC	2.638	Down-regulation
CMGC_MAPK_JNK_MAPK8_ST	P15336	ATF2	P45983	MAPK8	S136	P141L	141	Missense	distal	5	no	8.636	8.634	EPSD	COSMIC	2.638	Down-regulation
CMGC_MAPK_JNK_MAPK8_ST	P15336	ATF2	P45983	MAPK8	S136	P137S	137	Missense	proximal	1	no	8.636	0.907	EPSD	COSMIC	2.638	Loss
CMGC_MAPK_JNK_MAPK8_ST	P15336	ATF2	P45983	MAPK8	S257	V258I	258	Missense	proximal	1	no	0.814	3.684	EPSD	COSMIC;GDSC;CCLE	2.638	Gain
CMGC_MAPK_JNK_MAPK8_ST	P15336	ATF2	P45983	MAPK8	S265	S266P	266	Missense	proximal	1	no	-0.713	7.016	EPSD	COSMIC	2.638	Gain
CMGC_MAPK_JNK_MAPK8_ST	P15336	ATF2	P45983	MAPK8	S266	S266P	266	Missense	central	0	yes	7.697	0.000	EPSD	COSMIC	2.638	Loss
CMGC_MAPK_JNK_MAPK8_ST	P15336	ATF2	P45983	MAPK8	S266	P269Q	269	Missense	distal	3	no	7.697	7.628	EPSD	COSMIC	2.638	Down-regulation
CMGC_MAPK_JNK_MAPK8_ST	P15336	ATF2	P45983	MAPK8	S266	S265F	265	Missense	proximal	-1	no	7.697	7.668	EPSD	COSMIC;GDSC;CCLE	2.638	Down-regulation
CMGC_MAPK_JNK_MAPK8_ST	P15336	ATF2	P45983	MAPK8	S266	P269S	269	Missense	distal	3	no	7.697	7.572	EPSD	COSMIC	2.638	Down-regulation
CMGC_MAPK_JNK_MAPK8_ST	P15336	ATF2	P45983	MAPK8	T325	P326L	326	Missense	proximal	1	no	7.959	0.387	EPSD	COSMIC;GDSC	2.638	Loss
CMGC_MAPK_JNK_MAPK8_ST	P15336	ATF2	P45983	MAPK8	T325	P326T	326	Missense	proximal	1	no	7.959	0.972	EPSD	COSMIC	2.638	Loss
CMGC_MAPK_JNK_MAPK8_ST	P15336	ATF2	P45983	MAPK8	T325	H331Y	331	Missense	distal	6	no	7.959	7.921	EPSD	COSMIC	2.638	Down-regulation
CMGC_MAPK_JNK_MAPK8_ST	P15336	ATF2	P45983	MAPK8	S328	P326L	326	Missense	proximal	-2	no	8.292	8.099	EPSD	COSMIC;GDSC	2.638	Down-regulation
CMGC_MAPK_JNK_MAPK8_ST	P15336	ATF2	P45983	MAPK8	S328	P326T	326	Missense	proximal	-2	no	8.292	8.212	EPSD	COSMIC	2.638	Down-regulation
CMGC_MAPK_JNK_MAPK8_ST	P15336	ATF2	P45983	MAPK8	S328	Q335H	335	Missense	distal	7	no	8.292	8.327	EPSD	COSMIC	2.638	Up-regulation
CMGC_MAPK_JNK_MAPK8_ST	P15336	ATF2	P45983	MAPK8	S328	P334S	334	Missense	distal	6	no	8.292	8.316	EPSD	COSMIC	2.638	Up-regulation
CMGC_MAPK_JNK_MAPK8_ST	P15336	ATF2	P45983	MAPK8	S328	H331Y	331	Missense	distal	3	no	8.292	8.410	EPSD	COSMIC	2.638	Up-regulation
CMGC_MAPK_JNK_MAPK8_ST	P15336	ATF2	P45983	MAPK8	T333	Q337K	337	Missense	distal	4	no	7.887	8.049	EPSD	COSMIC	2.638	Up-regulation
CMGC_MAPK_JNK_MAPK8_ST	P15336	ATF2	P45983	MAPK8	T333	P326L	326	Missense	distal	-7	no	7.887	7.898	EPSD	COSMIC;GDSC	2.638	Up-regulation
CMGC_MAPK_JNK_MAPK8_ST	P15336	ATF2	P45983	MAPK8	T333	P326T	326	Missense	distal	-7	no	7.887	7.883	EPSD	COSMIC	2.638	Down-regulation
CMGC_MAPK_JNK_MAPK8_ST	P15336	ATF2	P45983	MAPK8	T333	Q335H	335	Missense	proximal	2	no	7.887	7.770	EPSD	COSMIC	2.638	Down-regulation
CMGC_MAPK_JNK_MAPK8_ST	P15336	ATF2	P45983	MAPK8	T333	P334S	334	Missense	proximal	1	no	7.887	0.158	EPSD	COSMIC	2.638	Loss
CMGC_MAPK_JNK_MAPK8_ST	P15336	ATF2	P45983	MAPK8	T333	H331Y	331	Missense	proximal	-2	no	7.887	7.837	EPSD	COSMIC	2.638	Down-regulation
CMGC_MAPK_JNK_MAPK8_ST	P15336	ATF2	P45983	MAPK8	S446	S442L	442	Missense	distal	-4	no	7.654	6.662	EPSD	COSMIC	2.638	Down-regulation
CMGC_MAPK_JNK_MAPK8_ST	P15336	ATF2	P45983	MAPK8	S446	P444L	444	Missense	proximal	-2	no	7.654	7.461	EPSD	COSMIC	2.638	Down-regulation
CMGC_MAPK_JNK_MAPK8_ST	P15336	ATF2	P45983	MAPK8	S446	P444T	444	Missense	proximal	-2	no	7.654	7.574	EPSD	COSMIC	2.638	Down-regulation
CMGC_MAPK_JNK_MAPK8_ST	P15336	ATF2	P45983	MAPK8	S446	S442P	442	Missense	distal	-4	no	7.654	6.989	EPSD	COSMIC	2.638	Down-regulation
CMGC_MAPK_JNK_MAPK8_ST	P15336	ATF2	P45983	MAPK8	S446	P444Q	444	Missense	proximal	-2	no	7.654	7.544	EPSD	COSMIC	2.638	Down-regulation
CMGC_MAPK_JNK_MAPK8_ST	P01106	MYC	P45983	MAPK8	T58	P57S	57	Missense	proximal	-1	no	7.250	7.260	EPSD	COSMIC;CCLE	2.638	Up-regulation
CMGC_MAPK_JNK_MAPK8_ST	P01106	MYC	P45983	MAPK8	T58	S62P	62	Missense	distal	4	no	7.250	7.225	EPSD	COSMIC;CCLE	2.638	Down-regulation
CMGC_MAPK_JNK_MAPK8_ST	P01106	MYC	P45983	MAPK8	T58	P59L	59	Missense	proximal	1	no	7.250	-0.323	EPSD	COSMIC;CCLE	2.638	Loss
CMGC_MAPK_JNK_MAPK8_ST	P01106	MYC	P45983	MAPK8	T58	T58N	58	Missense	central	0	yes	7.250	0.000	EPSD	COSMIC;CCLE	2.638	Loss
CMGC_MAPK_JNK_MAPK8_ST	P01106	MYC	P45983	MAPK8	T58	P60H	60	Missense	proximal	2	no	7.250	7.251	EPSD	COSMIC;CCLE	2.638	Up-regulation
CMGC_MAPK_JNK_MAPK8_ST	P01106	MYC	P45983	MAPK8	T58	P63L	63	Missense	distal	5	no	7.250	7.248	EPSD	COSMIC	2.638	Down-regulation
CMGC_MAPK_JNK_MAPK8_ST	P01106	MYC	P45983	MAPK8	T58	P63H	63	Missense	distal	5	no	7.250	7.217	EPSD	COSMIC	2.638	Down-regulation
CMGC_MAPK_JNK_MAPK8_ST	P01106	MYC	P45983	MAPK8	T58	T58A	58	Missense	central	0	yes	7.250	0.000	EPSD	COSMIC;CCLE	2.638	Loss
CMGC_MAPK_JNK_MAPK8_ST	P01106	MYC	P45983	MAPK8	T58	P59A	59	Missense	proximal	1	no	7.250	0.902	EPSD	COSMIC;CCLE	2.638	Loss
CMGC_MAPK_JNK_MAPK8_ST	P01106	MYC	P45983	MAPK8	T58	P59R	59	Missense	proximal	1	no	7.250	0.113	EPSD	COSMIC	2.638	Loss
CMGC_MAPK_JNK_MAPK8_ST	P01106	MYC	P45983	MAPK8	T58	P60A	60	Missense	proximal	2	no	7.250	7.459	EPSD	COSMIC;CCLE	2.638	Up-regulation
CMGC_MAPK_JNK_MAPK8_ST	P01106	MYC	P45983	MAPK8	T58	P57T	57	Missense	proximal	-1	no	7.250	7.261	EPSD	COSMIC;CCLE	2.638	Up-regulation
CMGC_MAPK_JNK_MAPK8_ST	P01106	MYC	P45983	MAPK8	T58	P59S	59	Missense	proximal	1	no	7.250	-0.479	EPSD	COSMIC;CCLE	2.638	Loss
CMGC_MAPK_JNK_MAPK8_ST	P01106	MYC	P45983	MAPK8	T58	S62F	62	Missense	distal	4	no	7.250	6.791	EPSD	COSMIC	2.638	Down-regulation
CMGC_MAPK_JNK_MAPK8_ST	P01106	MYC	P45983	MAPK8	T58	T58I	58	Missense	central	0	yes	7.250	0.000	EPSD	COSMIC;CCLE	2.638	Loss
CMGC_MAPK_JNK_MAPK8_ST	P01106	MYC	P45983	MAPK8	T58	K51N	51	Missense	distal	-7	no	7.250	7.268	EPSD	COSMIC	2.638	Up-regulation
CMGC_MAPK_JNK_MAPK8_ST	P01106	MYC	P45983	MAPK8	T58	T58P	58	Missense	central	0	yes	7.250	0.000	EPSD	COSMIC	2.638	Loss
CMGC_MAPK_JNK_MAPK8_ST	P01106	MYC	P45983	MAPK8	T58	S64R	64	Missense	distal	6	no	7.250	7.190	EPSD	COSMIC;CCLE	2.638	Down-regulation
CMGC_MAPK_JNK_MAPK8_ST	P01106	MYC	P45983	MAPK8	T58	P57L	57	Missense	proximal	-1	no	7.250	7.231	EPSD	COSMIC;CCLE	2.638	Down-regulation
CMGC_MAPK_JNK_MAPK8_ST	P01106	MYC	P45983	MAPK8	T58	P63S	63	Missense	distal	5	no	7.250	7.166	EPSD	COSMIC;CCLE	2.638	Down-regulation
CMGC_MAPK_JNK_MAPK8_ST	P01106	MYC	P45983	MAPK8	T58	P57F	57	Missense	proximal	-1	no	7.250	7.230	EPSD	COSMIC	2.638	Down-regulation
CMGC_MAPK_JNK_MAPK8_ST	P01106	MYC	P45983	MAPK8	T58	P59Q	59	Missense	proximal	1	no	7.250	0.140	EPSD	COSMIC;CCLE	2.638	Loss
CMGC_MAPK_JNK_MAPK8_ST	P01106	MYC	P45983	MAPK8	T58	P59T	59	Missense	proximal	1	no	7.250	0.263	EPSD	COSMIC	2.638	Loss
CMGC_MAPK_JNK_MAPK8_ST	P01106	MYC	P45983	MAPK8	T58	P60S	60	Missense	proximal	2	no	7.250	7.435	EPSD	COSMIC	2.638	Up-regulation
CMGC_MAPK_JNK_MAPK8_ST	P01106	MYC	P45983	MAPK8	T58	P63A	63	Missense	distal	5	no	7.250	7.175	EPSD	COSMIC	2.638	Down-regulation
CMGC_MAPK_JNK_MAPK8_ST	P01106	MYC	P45983	MAPK8	T58	S64N	64	Missense	distal	6	no	7.250	7.185	EPSD	COSMIC	2.638	Down-regulation
CMGC_MAPK_JNK_MAPK8_ST	P01106	MYC	P45983	MAPK8	T58	P60L	60	Missense	proximal	2	no	7.250	7.173	EPSD	COSMIC	2.638	Down-regulation
CMGC_MAPK_JNK_MAPK8_ST	P01106	MYC	P45983	MAPK8	T58	P57A	57	Missense	proximal	-1	no	7.250	7.261	EPSD	COSMIC	2.638	Up-regulation
CMGC_MAPK_JNK_MAPK8_ST	P01106	MYC	P45983	MAPK8	T58	L56V	56	Missense	proximal	-2	no	7.250	7.201	EPSD	COSMIC	2.638	Down-regulation
CMGC_MAPK_JNK_MAPK8_ST	P01106	MYC	P45983	MAPK8	T58	P63R	63	Missense	distal	5	no	7.250	7.238	EPSD	COSMIC	2.638	Down-regulation
CMGC_MAPK_JNK_MAPK8_ST	P01106	MYC	P45983	MAPK8	T58	L56M	56	Missense	proximal	-2	no	7.250	7.246	EPSD	COSMIC	2.638	Down-regulation
CMGC_MAPK_JNK_MAPK8_ST	P01106	MYC	P45983	MAPK8	T58	P63T	63	Missense	distal	5	no	7.250	7.173	EPSD	COSMIC	2.638	Down-regulation
CMGC_MAPK_JNK_MAPK8_ST	P01106	MYC	P45983	MAPK8	T58	S62A	62	Missense	distal	4	no	7.250	7.249	EPSD	COSMIC	2.638	Down-regulation
CMGC_MAPK_JNK_MAPK8_ST	P01106	MYC	P45983	MAPK8	T58	P57R	57	Missense	proximal	-1	no	7.250	7.234	EPSD	COSMIC	2.638	Down-regulation
CMGC_MAPK_JNK_MAPK8_ST	P01106	MYC	P45983	MAPK8	T58	P60T	60	Missense	proximal	2	no	7.250	7.438	EPSD	COSMIC;CCLE	2.638	Up-regulation
CMGC_MAPK_JNK_MAPK8_ST	P01106	MYC	P45983	MAPK8	T58	E54V	54	Missense	distal	-4	no	7.250	6.360	EPSD	COSMIC	2.638	Down-regulation
CMGC_MAPK_JNK_MAPK8_ST	P01106	MYC	P45983	MAPK8	T58	S64T	64	Missense	distal	6	no	7.250	7.247	EPSD	COSMIC	2.638	Down-regulation
CMGC_MAPK_JNK_MAPK8_ST	P01106	MYC	P45983	MAPK8	T58	R65C	65	Missense	distal	7	no	7.250	7.239	EPSD	COSMIC	2.638	Down-regulation
CMGC_MAPK_JNK_MAPK8_ST	P01106	MYC	P45983	MAPK8	T58	L55P	55	Missense	distal	-3	no	7.250	7.429	EPSD	COSMIC	2.638	Up-regulation
CMGC_MAPK_JNK_MAPK8_ST	P01106	MYC	P45983	MAPK8	T58	L55M	55	Missense	distal	-3	no	7.250	7.265	EPSD	COSMIC	2.638	Up-regulation
CMGC_MAPK_JNK_MAPK8_ST	P01106	MYC	P45983	MAPK8	T58	E54A	54	Missense	distal	-4	no	7.250	7.216	EPSD	COSMIC	2.638	Down-regulation
CMGC_MAPK_JNK_MAPK8_ST	P01106	MYC	P45983	MAPK8	S62	P57S	57	Missense	distal	-5	no	8.065	7.954	EPSD;PhosphoSitePlus	COSMIC;CCLE	2.638	Down-regulation
CMGC_MAPK_JNK_MAPK8_ST	P01106	MYC	P45983	MAPK8	S62	S62P	62	Missense	central	0	yes	8.065	0.000	EPSD;PhosphoSitePlus	COSMIC;CCLE	2.638	Loss
CMGC_MAPK_JNK_MAPK8_ST	P01106	MYC	P45983	MAPK8	S62	P59L	59	Missense	distal	-3	no	8.065	7.886	EPSD;PhosphoSitePlus	COSMIC;CCLE	2.638	Down-regulation
CMGC_MAPK_JNK_MAPK8_ST	P01106	MYC	P45983	MAPK8	S62	T58N	58	Missense	distal	-4	no	8.065	7.406	EPSD;PhosphoSitePlus	COSMIC;CCLE	2.638	Down-regulation
CMGC_MAPK_JNK_MAPK8_ST	P01106	MYC	P45983	MAPK8	S62	P60H	60	Missense	proximal	-2	no	8.065	7.881	EPSD;PhosphoSitePlus	COSMIC;CCLE	2.638	Down-regulation
CMGC_MAPK_JNK_MAPK8_ST	P01106	MYC	P45983	MAPK8	S62	P63L	63	Missense	proximal	1	no	8.065	0.493	EPSD;PhosphoSitePlus	COSMIC	2.638	Loss
CMGC_MAPK_JNK_MAPK8_ST	P01106	MYC	P45983	MAPK8	S62	P63H	63	Missense	proximal	1	no	8.065	0.150	EPSD;PhosphoSitePlus	COSMIC	2.638	Loss
CMGC_MAPK_JNK_MAPK8_ST	P01106	MYC	P45983	MAPK8	S62	T58A	58	Missense	distal	-4	no	8.065	8.102	EPSD;PhosphoSitePlus	COSMIC;CCLE	2.638	Up-regulation
CMGC_MAPK_JNK_MAPK8_ST	P01106	MYC	P45983	MAPK8	S62	P59A	59	Missense	distal	-3	no	8.065	8.263	EPSD;PhosphoSitePlus	COSMIC;CCLE	2.638	Up-regulation
CMGC_MAPK_JNK_MAPK8_ST	P01106	MYC	P45983	MAPK8	S62	P59R	59	Missense	distal	-3	no	8.065	7.923	EPSD;PhosphoSitePlus	COSMIC	2.638	Down-regulation
CMGC_MAPK_JNK_MAPK8_ST	P01106	MYC	P45983	MAPK8	S62	P60A	60	Missense	proximal	-2	no	8.065	8.015	EPSD;PhosphoSitePlus	COSMIC;CCLE	2.638	Down-regulation
CMGC_MAPK_JNK_MAPK8_ST	P01106	MYC	P45983	MAPK8	S62	P57T	57	Missense	distal	-5	no	8.065	7.953	EPSD;PhosphoSitePlus	COSMIC;CCLE	2.638	Down-regulation
CMGC_MAPK_JNK_MAPK8_ST	P01106	MYC	P45983	MAPK8	S62	P59S	59	Missense	distal	-3	no	8.065	8.228	EPSD;PhosphoSitePlus	COSMIC;CCLE	2.638	Up-regulation
CMGC_MAPK_JNK_MAPK8_ST	P01106	MYC	P45983	MAPK8	S62	S62F	62	Missense	central	0	yes	8.065	0.000	EPSD;PhosphoSitePlus	COSMIC	2.638	Loss
CMGC_MAPK_JNK_MAPK8_ST	P01106	MYC	P45983	MAPK8	S62	T58I	58	Missense	distal	-4	no	8.065	7.639	EPSD;PhosphoSitePlus	COSMIC;CCLE	2.638	Down-regulation
CMGC_MAPK_JNK_MAPK8_ST	P01106	MYC	P45983	MAPK8	S62	T58P	58	Missense	distal	-4	no	8.065	7.615	EPSD;PhosphoSitePlus	COSMIC	2.638	Down-regulation
CMGC_MAPK_JNK_MAPK8_ST	P01106	MYC	P45983	MAPK8	S62	S64R	64	Missense	proximal	2	no	8.065	7.824	EPSD;PhosphoSitePlus	COSMIC;CCLE	2.638	Down-regulation
CMGC_MAPK_JNK_MAPK8_ST	P01106	MYC	P45983	MAPK8	S62	P57L	57	Missense	distal	-5	no	8.065	8.426	EPSD;PhosphoSitePlus	COSMIC;CCLE	2.638	Up-regulation
CMGC_MAPK_JNK_MAPK8_ST	P01106	MYC	P45983	MAPK8	S62	P63S	63	Missense	proximal	1	no	8.065	0.337	EPSD;PhosphoSitePlus	COSMIC;CCLE	2.638	Loss
CMGC_MAPK_JNK_MAPK8_ST	P01106	MYC	P45983	MAPK8	S62	R66H	66	Missense	distal	4	no	8.065	8.102	EPSD;PhosphoSitePlus	COSMIC	2.638	Up-regulation
CMGC_MAPK_JNK_MAPK8_ST	P01106	MYC	P45983	MAPK8	S62	P57F	57	Missense	distal	-5	no	8.065	8.422	EPSD;PhosphoSitePlus	COSMIC	2.638	Up-regulation
CMGC_MAPK_JNK_MAPK8_ST	P01106	MYC	P45983	MAPK8	S62	P59Q	59	Missense	distal	-3	no	8.065	8.122	EPSD;PhosphoSitePlus	COSMIC;CCLE	2.638	Up-regulation
CMGC_MAPK_JNK_MAPK8_ST	P01106	MYC	P45983	MAPK8	S62	P59T	59	Missense	distal	-3	no	8.065	8.210	EPSD;PhosphoSitePlus	COSMIC	2.638	Up-regulation
CMGC_MAPK_JNK_MAPK8_ST	P01106	MYC	P45983	MAPK8	S62	P60S	60	Missense	proximal	-2	no	8.065	7.960	EPSD;PhosphoSitePlus	COSMIC	2.638	Down-regulation
CMGC_MAPK_JNK_MAPK8_ST	P01106	MYC	P45983	MAPK8	S62	P63A	63	Missense	proximal	1	no	8.065	1.718	EPSD;PhosphoSitePlus	COSMIC	2.638	Loss
CMGC_MAPK_JNK_MAPK8_ST	P01106	MYC	P45983	MAPK8	S62	S64N	64	Missense	proximal	2	no	8.065	7.804	EPSD;PhosphoSitePlus	COSMIC	2.638	Down-regulation
CMGC_MAPK_JNK_MAPK8_ST	P01106	MYC	P45983	MAPK8	S62	P60L	60	Missense	proximal	-2	no	8.065	7.872	EPSD;PhosphoSitePlus	COSMIC	2.638	Down-regulation
CMGC_MAPK_JNK_MAPK8_ST	P01106	MYC	P45983	MAPK8	S62	P57A	57	Missense	distal	-5	no	8.065	7.937	EPSD;PhosphoSitePlus	COSMIC	2.638	Down-regulation
CMGC_MAPK_JNK_MAPK8_ST	P01106	MYC	P45983	MAPK8	S62	L56V	56	Missense	distal	-6	no	8.065	8.090	EPSD;PhosphoSitePlus	COSMIC	2.638	Up-regulation
CMGC_MAPK_JNK_MAPK8_ST	P01106	MYC	P45983	MAPK8	S62	P63R	63	Missense	proximal	1	no	8.065	0.929	EPSD;PhosphoSitePlus	COSMIC	2.638	Loss
CMGC_MAPK_JNK_MAPK8_ST	P01106	MYC	P45983	MAPK8	S62	L56M	56	Missense	distal	-6	no	8.065	8.050	EPSD;PhosphoSitePlus	COSMIC	2.638	Down-regulation
CMGC_MAPK_JNK_MAPK8_ST	P01106	MYC	P45983	MAPK8	S62	L69V	69	Missense	distal	7	no	8.065	8.072	EPSD;PhosphoSitePlus	COSMIC	2.638	Up-regulation
CMGC_MAPK_JNK_MAPK8_ST	P01106	MYC	P45983	MAPK8	S62	P63T	63	Missense	proximal	1	no	8.065	1.079	EPSD;PhosphoSitePlus	COSMIC	2.638	Loss
CMGC_MAPK_JNK_MAPK8_ST	P01106	MYC	P45983	MAPK8	S62	S67F	67	Missense	distal	5	no	8.065	8.141	EPSD;PhosphoSitePlus	COSMIC	2.638	Up-regulation
CMGC_MAPK_JNK_MAPK8_ST	P01106	MYC	P45983	MAPK8	S62	S62A	62	Missense	central	0	yes	8.065	0.000	EPSD;PhosphoSitePlus	COSMIC	2.638	Loss
CMGC_MAPK_JNK_MAPK8_ST	P01106	MYC	P45983	MAPK8	S62	P57R	57	Missense	distal	-5	no	8.065	8.358	EPSD;PhosphoSitePlus	COSMIC	2.638	Up-regulation
CMGC_MAPK_JNK_MAPK8_ST	P01106	MYC	P45983	MAPK8	S62	L69P	69	Missense	distal	7	no	8.065	8.026	EPSD;PhosphoSitePlus	COSMIC	2.638	Down-regulation
CMGC_MAPK_JNK_MAPK8_ST	P01106	MYC	P45983	MAPK8	S62	P60T	60	Missense	proximal	-2	no	8.065	7.985	EPSD;PhosphoSitePlus	COSMIC;CCLE	2.638	Down-regulation
CMGC_MAPK_JNK_MAPK8_ST	P01106	MYC	P45983	MAPK8	S62	L69F	69	Missense	distal	7	no	8.065	8.062	EPSD;PhosphoSitePlus	COSMIC	2.638	Down-regulation
CMGC_MAPK_JNK_MAPK8_ST	P01106	MYC	P45983	MAPK8	S62	S64T	64	Missense	proximal	2	no	8.065	8.069	EPSD;PhosphoSitePlus	COSMIC	2.638	Up-regulation
CMGC_MAPK_JNK_MAPK8_ST	P01106	MYC	P45983	MAPK8	S62	R65C	65	Missense	distal	3	no	8.065	8.048	EPSD;PhosphoSitePlus	COSMIC	2.638	Down-regulation
CMGC_MAPK_JNK_MAPK8_ST	P01106	MYC	P45983	MAPK8	S62	L55P	55	Missense	distal	-7	no	8.065	8.054	EPSD;PhosphoSitePlus	COSMIC	2.638	Down-regulation
CMGC_MAPK_JNK_MAPK8_ST	P01106	MYC	P45983	MAPK8	S62	L55M	55	Missense	distal	-7	no	8.065	8.063	EPSD;PhosphoSitePlus	COSMIC	2.638	Down-regulation
CMGC_MAPK_JNK_MAPK8_ST	P01106	MYC	P45983	MAPK8	S71	C70R	70	Missense	proximal	-1	no	8.539	8.533	PhosphoSitePlus;EPSD	COSMIC	2.638	Down-regulation
CMGC_MAPK_JNK_MAPK8_ST	P01106	MYC	P45983	MAPK8	S71	S64R	64	Missense	distal	-7	no	8.539	8.553	PhosphoSitePlus;EPSD	COSMIC;CCLE	2.638	Up-regulation
CMGC_MAPK_JNK_MAPK8_ST	P01106	MYC	P45983	MAPK8	S71	R66H	66	Missense	distal	-5	no	8.539	8.444	PhosphoSitePlus;EPSD	COSMIC	2.638	Down-regulation
CMGC_MAPK_JNK_MAPK8_ST	P01106	MYC	P45983	MAPK8	S71	A76V	76	Missense	distal	5	no	8.539	8.612	PhosphoSitePlus;EPSD	COSMIC	2.638	Up-regulation
CMGC_MAPK_JNK_MAPK8_ST	P01106	MYC	P45983	MAPK8	S71	V77I	77	Missense	distal	6	no	8.539	8.585	PhosphoSitePlus;EPSD	COSMIC;CCLE	2.638	Up-regulation
CMGC_MAPK_JNK_MAPK8_ST	P01106	MYC	P45983	MAPK8	S71	S71L	71	Missense	central	0	yes	8.539	0.000	PhosphoSitePlus;EPSD	COSMIC	2.638	Loss
CMGC_MAPK_JNK_MAPK8_ST	P01106	MYC	P45983	MAPK8	S71	S64N	64	Missense	distal	-7	no	8.539	8.554	PhosphoSitePlus;EPSD	COSMIC	2.638	Up-regulation
CMGC_MAPK_JNK_MAPK8_ST	P01106	MYC	P45983	MAPK8	S71	Y74N	74	Missense	distal	3	no	8.539	8.462	PhosphoSitePlus;EPSD	COSMIC;CCLE	2.638	Down-regulation
CMGC_MAPK_JNK_MAPK8_ST	P01106	MYC	P45983	MAPK8	S71	L69V	69	Missense	proximal	-2	no	8.539	8.491	PhosphoSitePlus;EPSD	COSMIC	2.638	Down-regulation
CMGC_MAPK_JNK_MAPK8_ST	P01106	MYC	P45983	MAPK8	S71	V77G	77	Missense	distal	6	no	8.539	8.561	PhosphoSitePlus;EPSD	COSMIC	2.638	Up-regulation
CMGC_MAPK_JNK_MAPK8_ST	P01106	MYC	P45983	MAPK8	S71	Y74H	74	Missense	distal	3	no	8.539	8.422	PhosphoSitePlus;EPSD	COSMIC	2.638	Down-regulation
CMGC_MAPK_JNK_MAPK8_ST	P01106	MYC	P45983	MAPK8	S71	S67F	67	Missense	distal	-4	no	8.539	7.601	PhosphoSitePlus;EPSD	COSMIC	2.638	Down-regulation
CMGC_MAPK_JNK_MAPK8_ST	P01106	MYC	P45983	MAPK8	S71	V75I	75	Missense	distal	4	no	8.539	8.869	PhosphoSitePlus;EPSD	COSMIC	2.638	Up-regulation
CMGC_MAPK_JNK_MAPK8_ST	P01106	MYC	P45983	MAPK8	S71	L69P	69	Missense	proximal	-2	no	8.539	8.732	PhosphoSitePlus;EPSD	COSMIC	2.638	Up-regulation
CMGC_MAPK_JNK_MAPK8_ST	P01106	MYC	P45983	MAPK8	S71	C70W	70	Missense	proximal	-1	no	8.539	8.529	PhosphoSitePlus;EPSD	COSMIC	2.638	Down-regulation
CMGC_MAPK_JNK_MAPK8_ST	P01106	MYC	P45983	MAPK8	S71	S71W	71	Missense	central	0	yes	8.539	0.000	PhosphoSitePlus;EPSD	COSMIC	2.638	Loss
CMGC_MAPK_JNK_MAPK8_ST	P01106	MYC	P45983	MAPK8	S71	L69F	69	Missense	proximal	-2	no	8.539	8.512	PhosphoSitePlus;EPSD	COSMIC	2.638	Down-regulation
CMGC_MAPK_JNK_MAPK8_ST	P01106	MYC	P45983	MAPK8	S71	S73P	73	Missense	proximal	2	no	8.539	8.354	PhosphoSitePlus;EPSD	COSMIC	2.638	Down-regulation
CMGC_MAPK_JNK_MAPK8_ST	P01106	MYC	P45983	MAPK8	S71	S64T	64	Missense	distal	-7	no	8.539	8.541	PhosphoSitePlus;EPSD	COSMIC	2.638	Up-regulation
CMGC_MAPK_JNK_MAPK8_ST	P01106	MYC	P45983	MAPK8	S71	R65C	65	Missense	distal	-6	no	8.539	8.514	PhosphoSitePlus;EPSD	COSMIC	2.638	Down-regulation
CMGC_MAPK_JNK_MAPK8_ST	P01106	MYC	P45983	MAPK8	S71	P72F	72	Missense	proximal	1	no	8.539	0.367	PhosphoSitePlus;EPSD	COSMIC	2.638	Loss
CMGC_MAPK_JNK_MAPK8_ST	P01106	MYC	P45983	MAPK8	S71	P72R	72	Missense	proximal	1	no	8.539	1.403	PhosphoSitePlus;EPSD	COSMIC	2.638	Loss
CMGC_MAPK_JNK_MAPK8_ST	P01106	MYC	P45983	MAPK8	T78	S81F	81	Missense	distal	3	no	6.974	7.194	EPSD	COSMIC;CCLE	2.638	Up-regulation
CMGC_MAPK_JNK_MAPK8_ST	P01106	MYC	P45983	MAPK8	T78	R83Q	83	Missense	distal	5	no	6.974	6.923	EPSD	COSMIC	2.638	Down-regulation
CMGC_MAPK_JNK_MAPK8_ST	P01106	MYC	P45983	MAPK8	T78	A76V	76	Missense	proximal	-2	no	6.974	6.783	EPSD	COSMIC	2.638	Down-regulation
CMGC_MAPK_JNK_MAPK8_ST	P01106	MYC	P45983	MAPK8	T78	V77I	77	Missense	proximal	-1	no	6.974	6.996	EPSD	COSMIC;CCLE	2.638	Up-regulation
CMGC_MAPK_JNK_MAPK8_ST	P01106	MYC	P45983	MAPK8	T78	S71L	71	Missense	distal	-7	no	6.974	6.992	EPSD	COSMIC	2.638	Up-regulation
CMGC_MAPK_JNK_MAPK8_ST	P01106	MYC	P45983	MAPK8	T78	L82V	82	Missense	distal	4	no	6.974	6.887	EPSD	COSMIC	2.638	Down-regulation
CMGC_MAPK_JNK_MAPK8_ST	P01106	MYC	P45983	MAPK8	T78	G84R	84	Missense	distal	6	no	6.974	6.971	EPSD	COSMIC	2.638	Down-regulation
CMGC_MAPK_JNK_MAPK8_ST	P01106	MYC	P45983	MAPK8	T78	P79S	79	Missense	proximal	1	no	6.974	-0.755	EPSD	COSMIC	2.638	Loss
CMGC_MAPK_JNK_MAPK8_ST	P01106	MYC	P45983	MAPK8	T78	Y74N	74	Missense	distal	-4	no	6.974	7.334	EPSD	COSMIC;CCLE	2.638	Up-regulation
CMGC_MAPK_JNK_MAPK8_ST	P01106	MYC	P45983	MAPK8	T78	F80L	80	Missense	proximal	2	no	6.974	6.984	EPSD	COSMIC	2.638	Up-regulation
CMGC_MAPK_JNK_MAPK8_ST	P01106	MYC	P45983	MAPK8	T78	D85Y	85	Missense	distal	7	no	6.974	7.028	EPSD	COSMIC	2.638	Up-regulation
CMGC_MAPK_JNK_MAPK8_ST	P01106	MYC	P45983	MAPK8	T78	V77G	77	Missense	proximal	-1	no	6.974	6.984	EPSD	COSMIC	2.638	Up-regulation
CMGC_MAPK_JNK_MAPK8_ST	P01106	MYC	P45983	MAPK8	T78	S81C	81	Missense	distal	3	no	6.974	7.139	EPSD	COSMIC	2.638	Up-regulation
CMGC_MAPK_JNK_MAPK8_ST	P01106	MYC	P45983	MAPK8	T78	Y74H	74	Missense	distal	-4	no	6.974	7.464	EPSD	COSMIC	2.638	Up-regulation
CMGC_MAPK_JNK_MAPK8_ST	P01106	MYC	P45983	MAPK8	T78	D85E	85	Missense	distal	7	no	6.974	6.934	EPSD	COSMIC	2.638	Down-regulation
CMGC_MAPK_JNK_MAPK8_ST	P01106	MYC	P45983	MAPK8	T78	V75I	75	Missense	distal	-3	no	6.974	7.209	EPSD	COSMIC	2.638	Up-regulation
CMGC_MAPK_JNK_MAPK8_ST	P01106	MYC	P45983	MAPK8	T78	S71W	71	Missense	distal	-7	no	6.974	6.991	EPSD	COSMIC	2.638	Up-regulation
CMGC_MAPK_JNK_MAPK8_ST	P01106	MYC	P45983	MAPK8	T78	L82H	82	Missense	distal	4	no	6.974	7.078	EPSD	COSMIC	2.638	Up-regulation
CMGC_MAPK_JNK_MAPK8_ST	P01106	MYC	P45983	MAPK8	T78	S73P	73	Missense	distal	-5	no	6.974	7.086	EPSD	COSMIC	2.638	Up-regulation
CMGC_MAPK_JNK_MAPK8_ST	P01106	MYC	P45983	MAPK8	T78	P72F	72	Missense	distal	-6	no	6.974	7.066	EPSD	COSMIC	2.638	Up-regulation
CMGC_MAPK_JNK_MAPK8_ST	P01106	MYC	P45983	MAPK8	T78	P72R	72	Missense	distal	-6	no	6.974	7.040	EPSD	COSMIC	2.638	Up-regulation
CMGC_MAPK_JNK_MAPK8_ST	P01106	MYC	P45983	MAPK8	S161	K157T	157	Missense	distal	-4	no	9.867	9.540	EPSD	COSMIC	2.638	Down-regulation
CMGC_MAPK_JNK_MAPK8_ST	P01106	MYC	P45983	MAPK8	S161	A155S	155	Missense	distal	-6	no	9.867	9.864	EPSD	COSMIC	2.638	Down-regulation
CMGC_MAPK_JNK_MAPK8_ST	P01106	MYC	P45983	MAPK8	S161	K157N	157	Missense	distal	-4	no	9.867	8.881	EPSD	COSMIC	2.638	Down-regulation
CMGC_MAPK_JNK_MAPK8_ST	P01106	MYC	P45983	MAPK8	S161	A155T	155	Missense	distal	-6	no	9.867	9.889	EPSD	COSMIC	2.638	Up-regulation
CMGC_MAPK_JNK_MAPK8_ST	P01106	MYC	P45983	MAPK8	S161	N163K	163	Missense	proximal	2	no	9.867	10.210	EPSD	COSMIC	2.638	Up-regulation
CMGC_MAPK_JNK_MAPK8_ST	P01106	MYC	P45983	MAPK8	S161	P162R	162	Missense	proximal	1	no	9.867	2.731	EPSD	COSMIC	2.638	Down-regulation
CMGC_MAPK_JNK_MAPK8_ST	P01106	MYC	P45983	MAPK8	S161	A154T	154	Missense	distal	-7	no	9.867	9.868	EPSD	COSMIC	2.638	Up-regulation
CMGC_MAPK_JNK_MAPK8_ST	P01106	MYC	P45983	MAPK8	S161	G160D	160	Missense	proximal	-1	no	9.867	9.878	EPSD	COSMIC	2.638	Up-regulation
CMGC_MAPK_JNK_MAPK8_ST	P01106	MYC	P45983	MAPK8	S161	S159N	159	Missense	proximal	-2	no	9.867	9.749	EPSD	COSMIC	2.638	Down-regulation
CMGC_MAPK_JNK_MAPK8_ST	P01106	MYC	P45983	MAPK8	S161	A165T	165	Missense	distal	4	no	9.867	9.818	EPSD	COSMIC	2.638	Down-regulation
CMGC_MAPK_JNK_MAPK8_ST	P01106	MYC	P45983	MAPK8	S161	S159T	159	Missense	proximal	-2	no	9.867	9.892	EPSD	COSMIC	2.638	Up-regulation
CMGC_MAPK_JNK_MAPK8_ST	P01106	MYC	P45983	MAPK8	S161	D158G	158	Missense	distal	-3	no	9.867	9.773	EPSD	COSMIC	2.638	Down-regulation
CMGC_MAPK_JNK_MAPK8_ST	P01106	MYC	P45983	MAPK8	S161	R166H	166	Missense	distal	5	no	9.867	9.846	EPSD	COSMIC	2.638	Down-regulation
CMGC_MAPK_JNK_MAPK8_ST	P01106	MYC	P45983	MAPK8	S161	S161N	161	Missense	central	0	yes	9.867	0.000	EPSD	COSMIC	2.638	Loss
CMGC_MAPK_JNK_MAPK8_ST	P01106	MYC	P45983	MAPK8	S161	R156G	156	Missense	distal	-5	no	9.867	9.839	EPSD	COSMIC	2.638	Down-regulation
CMGC_MAPK_JNK_MAPK8_ST	P01106	MYC	P45983	MAPK8	S161	A154G	154	Missense	distal	-7	no	9.867	9.880	EPSD	COSMIC	2.638	Up-regulation
CMGC_MAPK_JNK_MAPK8_ST	P01106	MYC	P45983	MAPK8	S161	S159R	159	Missense	proximal	-2	no	9.867	9.789	EPSD	COSMIC	2.638	Down-regulation
CMGC_MAPK_JNK_MAPK8_ST	P01106	MYC	P45983	MAPK8	S161	A165D	165	Missense	distal	4	no	9.867	9.665	EPSD	COSMIC	2.638	Down-regulation
CMGC_MAPK_JNK_MAPK8_ST	P01106	MYC	P45983	MAPK8	S204	P198S	198	Missense	distal	-6	no	8.001	7.912	EPSD	COSMIC	2.638	Down-regulation
CMGC_MAPK_JNK_MAPK8_ST	P01106	MYC	P45983	MAPK8	S204	S203R	203	Missense	proximal	-1	no	8.001	7.976	EPSD	COSMIC	2.638	Down-regulation
CMGC_MAPK_JNK_MAPK8_ST	P01106	MYC	P45983	MAPK8	S204	S203N	203	Missense	proximal	-1	no	8.001	7.973	EPSD	COSMIC;CCLE	2.638	Down-regulation
CMGC_MAPK_JNK_MAPK8_ST	P01106	MYC	P45983	MAPK8	S204	Y197D	197	Missense	distal	-7	no	8.001	7.988	EPSD	COSMIC	2.638	Down-regulation
CMGC_MAPK_JNK_MAPK8_ST	P01106	MYC	P45983	MAPK8	S204	S203T	203	Missense	proximal	-1	no	8.001	8.002	EPSD	COSMIC	2.638	Up-regulation
CMGC_MAPK_JNK_MAPK8_ST	P01106	MYC	P45983	MAPK8	S204	S203I	203	Missense	proximal	-1	no	8.001	7.989	EPSD	COSMIC	2.638	Down-regulation
CMGC_MAPK_JNK_MAPK8_ST	P01106	MYC	P45983	MAPK8	S204	Q211R	211	Missense	distal	7	no	8.001	8.047	EPSD	COSMIC	2.638	Up-regulation
CMGC_MAPK_JNK_MAPK8_ST	P01106	MYC	P45983	MAPK8	S204	P205S	205	Missense	proximal	1	no	8.001	0.272	EPSD	COSMIC	2.638	Loss
CMGC_MAPK_JNK_MAPK8_ST	P01106	MYC	P45983	MAPK8	S204	N200I	200	Missense	distal	-4	no	8.001	8.234	EPSD	COSMIC	2.638	Up-regulation
CMGC_MAPK_JNK_MAPK8_ST	P01106	MYC	P45983	MAPK8	S204	S204A	204	Missense	central	0	yes	8.001	0.000	EPSD	COSMIC	2.638	Loss
CMGC_MAPK_JNK_MAPK8_ST	P01106	MYC	P45983	MAPK8	S204	S202T	202	Missense	proximal	-2	no	8.001	8.027	EPSD	COSMIC	2.638	Up-regulation
CMGC_MAPK_JNK_MAPK8_ST	P01106	MYC	P45983	MAPK8	S204	S207P	207	Missense	distal	3	no	8.001	8.127	EPSD	COSMIC	2.638	Up-regulation
CMGC_MAPK_JNK_MAPK8_ST	P01106	MYC	P45983	MAPK8	S281	S283F	283	Missense	proximal	2	no	7.518	7.246	EPSD	COSMIC	2.638	Down-regulation
CMGC_MAPK_JNK_MAPK8_ST	P01106	MYC	P45983	MAPK8	S281	S277L	277	Missense	distal	-4	no	7.518	6.526	EPSD	COSMIC	2.638	Down-regulation
CMGC_MAPK_JNK_MAPK8_ST	P01106	MYC	P45983	MAPK8	S281	H287Q	287	Missense	distal	6	no	7.518	7.551	EPSD	COSMIC	2.638	Up-regulation
CMGC_MAPK_JNK_MAPK8_ST	P01106	MYC	P45983	MAPK8	S281	S279C	279	Missense	proximal	-2	no	7.518	7.454	EPSD	COSMIC	2.638	Down-regulation
CMGC_MAPK_JNK_MAPK8_ST	P01106	MYC	P45983	MAPK8	S281	S283Y	283	Missense	proximal	2	no	7.518	7.141	EPSD	COSMIC	2.638	Down-regulation
CMGC_MAPK_JNK_MAPK8_ST	P01106	MYC	P45983	MAPK8	S281	P282A	282	Missense	proximal	1	no	7.518	1.170	EPSD	COSMIC	2.638	Loss
CMGC_MAPK_JNK_MAPK8_ST	P01106	MYC	P45983	MAPK8	S281	G285E	285	Missense	distal	4	no	7.518	7.811	EPSD	COSMIC	2.638	Up-regulation
CMGC_MAPK_JNK_MAPK8_ST	P01106	MYC	P45983	MAPK8	S281	G280R	280	Missense	proximal	-1	no	7.518	7.517	EPSD	COSMIC	2.638	Down-regulation
CMGC_MAPK_JNK_MAPK8_ST	P01106	MYC	P45983	MAPK8	S281	G274D	274	Missense	distal	-7	no	7.518	7.513	EPSD	COSMIC	2.638	Down-regulation
CMGC_MAPK_JNK_MAPK8_ST	P01106	MYC	P45983	MAPK8	S281	S281F	281	Missense	central	0	yes	7.518	0.000	EPSD	COSMIC	2.638	Loss
CMGC_MAPK_JNK_MAPK8_ST	P01106	MYC	P45983	MAPK8	S293	S293C	293	Missense	central	0	yes	8.548	0.000	EPSD	COSMIC	2.638	Loss
CMGC_MAPK_JNK_MAPK8_ST	P01106	MYC	P45983	MAPK8	S293	C300Y	300	Missense	distal	7	no	8.548	8.589	EPSD	COSMIC	2.638	Up-regulation
CMGC_MAPK_JNK_MAPK8_ST	P01106	MYC	P45983	MAPK8	S293	P290T	290	Missense	distal	-3	no	8.548	8.692	EPSD	COSMIC	2.638	Up-regulation
CMGC_MAPK_JNK_MAPK8_ST	P01106	MYC	P45983	MAPK8	S293	H287Q	287	Missense	distal	-6	no	8.548	8.468	EPSD	COSMIC	2.638	Down-regulation
CMGC_MAPK_JNK_MAPK8_ST	P01106	MYC	P45983	MAPK8	S293	C300S	300	Missense	distal	7	no	8.548	8.496	EPSD	COSMIC	2.638	Down-regulation
CMGC_MAPK_JNK_MAPK8_ST	P01106	MYC	P45983	MAPK8	S293	L295V	295	Missense	proximal	2	no	8.548	8.517	EPSD	COSMIC	2.638	Down-regulation
CMGC_MAPK_JNK_MAPK8_ST	P01106	MYC	P45983	MAPK8	S293	P290H	290	Missense	distal	-3	no	8.548	8.443	EPSD	COSMIC	2.638	Down-regulation
CMGC_MAPK_JNK_MAPK8_ST	P01106	MYC	P45983	MAPK8	S293	L297F	297	Missense	distal	4	no	8.548	8.522	EPSD	COSMIC	2.638	Down-regulation
CMGC_MAPK_JNK_MAPK8_ST	P01106	MYC	P45983	MAPK8	S293	P290S	290	Missense	distal	-3	no	8.548	8.711	EPSD	COSMIC	2.638	Up-regulation
CMGC_MAPK_JNK_MAPK8_ST	P01106	MYC	P45983	MAPK8	S293	S293R	293	Missense	central	0	yes	8.548	0.000	EPSD	COSMIC	2.638	Loss
CMGC_MAPK_JNK_MAPK8_ST	P01106	MYC	P45983	MAPK8	S293	V296F	296	Missense	distal	3	no	8.548	8.522	EPSD	COSMIC	2.638	Down-regulation
CMGC_MAPK_JNK_MAPK8_ST	P01106	MYC	P45983	MAPK8	T315	P313L	313	Missense	proximal	-2	no	2.645	2.453	EPSD	COSMIC	2.638	Loss
CMGC_MAPK_JNK_MAPK8_ST	P01106	MYC	P45983	MAPK8	T315	D318N	318	Missense	distal	3	no	2.645	2.729	EPSD	COSMIC	2.638	Up-regulation
CMGC_MAPK_JNK_MAPK8_ST	P01106	MYC	P45983	MAPK8	T315	A321T	321	Missense	distal	6	no	2.645	2.646	EPSD	COSMIC	2.638	Up-regulation
CMGC_MAPK_JNK_MAPK8_ST	P01106	MYC	P45983	MAPK8	T315	A311G	311	Missense	distal	-4	no	2.645	1.934	EPSD	COSMIC	2.638	Loss
CMGC_MAPK_JNK_MAPK8_ST	P01106	MYC	P45983	MAPK8	T315	P312L	312	Missense	distal	-3	no	2.645	2.466	EPSD	COSMIC	2.638	Loss
CMGC_MAPK_JNK_MAPK8_ST	P01106	MYC	P45983	MAPK8	T315	A310T	310	Missense	distal	-5	no	2.645	2.662	EPSD	COSMIC	2.638	Up-regulation
CMGC_MAPK_JNK_MAPK8_ST	P01106	MYC	P45983	MAPK8	T315	K317R	317	Missense	proximal	2	no	2.645	2.323	EPSD	COSMIC	2.638	Loss
CMGC_MAPK_JNK_MAPK8_ST	P01106	MYC	P45983	MAPK8	T315	S314F	314	Missense	proximal	-1	no	2.645	2.616	EPSD	COSMIC	2.638	Loss
CMGC_MAPK_JNK_MAPK8_ST	P01106	MYC	P45983	MAPK8	T315	A321V	321	Missense	distal	6	no	2.645	2.570	EPSD	COSMIC	2.638	Loss
CMGC_MAPK_JNK_MAPK8_ST	P01106	MYC	P45983	MAPK8	S344	S347F	347	Missense	distal	3	no	7.193	7.412	EPSD	COSMIC	2.638	Up-regulation
CMGC_MAPK_JNK_MAPK8_ST	P01106	MYC	P45983	MAPK8	S344	E351K	351	Missense	distal	7	no	7.193	7.178	EPSD	COSMIC	2.638	Down-regulation
CMGC_MAPK_JNK_MAPK8_ST	P01106	MYC	P45983	MAPK8	S344	S337T	337	Missense	distal	-7	no	7.193	7.194	EPSD	COSMIC	2.638	Up-regulation
CMGC_MAPK_JNK_MAPK8_ST	P01106	MYC	P45983	MAPK8	S347	S347F	347	Missense	central	0	yes	2.774	0.000	EPSD	COSMIC	2.638	Loss
CMGC_MAPK_JNK_MAPK8_ST	P01106	MYC	P45983	MAPK8	S347	V354D	354	Missense	distal	7	no	2.774	2.729	EPSD	COSMIC	2.638	Down-regulation
CMGC_MAPK_JNK_MAPK8_ST	P01106	MYC	P45983	MAPK8	S347	E351K	351	Missense	distal	4	no	2.774	2.855	EPSD	COSMIC	2.638	Up-regulation
CMGC_MAPK_JNK_MAPK8_ST	P01106	MYC	P45983	MAPK8	S347	E352G	352	Missense	distal	5	no	2.774	2.853	EPSD	COSMIC	2.638	Up-regulation
CMGC_MAPK_JNK_MAPK8_ST	P05067	APP	P45983	MAPK8	T381	E380Q	380	Missense	proximal	-1	no	7.538	7.529	EPSD	COSMIC	2.638	Down-regulation
CMGC_MAPK_JNK_MAPK8_ST	P05067	APP	P45983	MAPK8	T381	K377R	377	Missense	distal	-4	no	7.538	6.625	EPSD	COSMIC	2.638	Down-regulation
CMGC_MAPK_JNK_MAPK8_ST	P05067	APP	P45983	MAPK8	T381	D376G	376	Missense	distal	-5	no	7.538	7.690	EPSD	COSMIC	2.638	Up-regulation
CMGC_MAPK_JNK_MAPK8_ST	P05067	APP	P45983	MAPK8	T381	G383W	383	Missense	proximal	2	no	7.538	7.427	EPSD	COSMIC	2.638	Down-regulation
CMGC_MAPK_JNK_MAPK8_ST	P05067	APP	P45983	MAPK8	T381	V375I	375	Missense	distal	-6	no	7.538	7.427	EPSD	COSMIC	2.638	Down-regulation
CMGC_MAPK_JNK_MAPK8_ST	P05067	APP	P45983	MAPK8	T381	N386S	386	Missense	distal	5	no	7.538	7.469	EPSD	COSMIC	2.638	Down-regulation
CMGC_MAPK_JNK_MAPK8_ST	P05067	APP	P45983	MAPK8	T743	V742L	742	Missense	proximal	-1	no	9.063	9.068	EPSD	COSMIC	2.638	Up-regulation
CMGC_MAPK_JNK_MAPK8_ST	P05067	APP	P45983	MAPK8	T743	E745K	745	Missense	proximal	2	no	9.063	9.081	EPSD	COSMIC	2.638	Up-regulation
CMGC_MAPK_JNK_MAPK8_ST	O43524	FOXO3	P45983	MAPK8	S7	A2V	2	Missense	distal	-5	no	8.070	8.611	EPSD	COSMIC;CCLE	2.638	Up-regulation
CMGC_MAPK_JNK_MAPK8_ST	O43524	FOXO3	P45983	MAPK8	S7	A6S	6	Missense	proximal	-1	no	8.070	8.068	EPSD	COSMIC	2.638	Down-regulation
CMGC_MAPK_JNK_MAPK8_ST	O43524	FOXO3	P45983	MAPK8	S12	A6S	6	Missense	distal	-6	no	7.207	7.204	EPSD	COSMIC	2.638	Down-regulation
CMGC_MAPK_JNK_MAPK8_ST	O43524	FOXO3	P45983	MAPK8	S43	E50D	50	Missense	distal	7	no	8.792	8.832	EPSD	COSMIC;CCLE	2.638	Up-regulation
CMGC_MAPK_JNK_MAPK8_ST	O43524	FOXO3	P45983	MAPK8	S280	Q275R	275	Missense	distal	-5	no	2.651	2.965	EPSD	COSMIC	2.638	Up-regulation
CMGC_MAPK_JNK_MAPK8_ST	O43524	FOXO3	P45983	MAPK8	S294	P295L	295	Missense	proximal	1	no	8.470	0.897	EPSD	COSMIC	2.638	Loss
CMGC_MAPK_JNK_MAPK8_ST	O43524	FOXO3	P45983	MAPK8	S311	S318C	318	Missense	distal	7	no	2.674	2.727	EPSD	COSMIC	2.638	Up-regulation
CMGC_MAPK_JNK_MAPK8_ST	O43524	FOXO3	P45983	MAPK8	S325	S318C	318	Missense	distal	-7	no	8.338	8.350	EPSD	COSMIC	2.638	Up-regulation
CMGC_MAPK_JNK_MAPK8_ST	O43524	FOXO3	P45983	MAPK8	S325	R323C	323	Missense	proximal	-2	no	8.338	8.352	EPSD	COSMIC	2.638	Up-regulation
CMGC_MAPK_JNK_MAPK8_ST	O43524	FOXO3	P45983	MAPK8	S325	E332Q	332	Missense	distal	7	no	8.338	8.355	EPSD	COSMIC;CCLE	2.638	Up-regulation
CMGC_MAPK_JNK_MAPK8_ST	O43524	FOXO3	P45983	MAPK8	S325	R323H	323	Missense	proximal	-2	no	8.338	8.337	EPSD	COSMIC	2.638	Down-regulation
CMGC_MAPK_JNK_MAPK8_ST	O43524	FOXO3	P45983	MAPK8	S344	A341T	341	Missense	distal	-3	no	7.791	7.737	EPSD	COSMIC	2.638	Down-regulation
CMGC_MAPK_JNK_MAPK8_ST	O43524	FOXO3	P45983	MAPK8	S355	P361L	361	Missense	distal	6	no	8.320	8.273	EPSD	COSMIC;GDSC;CCLE	2.638	Down-regulation
CMGC_MAPK_JNK_MAPK8_ST	O43524	FOXO3	P45983	MAPK8	S402	P397R	397	Missense	distal	-5	no	7.290	7.582	EPSD	COSMIC	2.638	Up-regulation
CMGC_MAPK_JNK_MAPK8_ST	O43524	FOXO3	P45983	MAPK8	S411	F414Y	414	Missense	distal	3	no	2.727	2.789	EPSD	COSMIC	2.638	Up-regulation
CMGC_MAPK_JNK_MAPK8_ST	O43524	FOXO3	P45983	MAPK8	S425	G424V	424	Missense	proximal	-1	no	9.449	9.440	EPSD	COSMIC	2.638	Down-regulation
CMGC_MAPK_JNK_MAPK8_ST	O43524	FOXO3	P45983	MAPK8	S588	T582P	582	Missense	distal	-6	no	3.500	3.564	EPSD	COSMIC	2.638	Up-regulation
CMGC_MAPK_JNK_MAPK8_ST	P10276	RARA	P45983	MAPK8	S74	P73S	73	Missense	proximal	-1	no	7.189	7.199	EPSD	COSMIC	2.638	Up-regulation
CMGC_MAPK_JNK_MAPK8_ST	P10276	RARA	P45983	MAPK8	S77	R83H	83	Missense	distal	6	no	7.003	7.015	EPSD	COSMIC;GDSC;CCLE	2.638	Up-regulation
CMGC_MAPK_JNK_MAPK8_ST	P10276	RARA	P45983	MAPK8	S77	R83C	83	Missense	distal	6	no	7.003	7.015	EPSD	COSMIC	2.638	Up-regulation
CMGC_MAPK_JNK_MAPK8_ST	P10276	RARA	P45983	MAPK8	S77	P73S	73	Missense	distal	-4	no	7.003	7.668	EPSD	COSMIC	2.638	Up-regulation
CMGC_MAPK_JNK_MAPK8_ST	P10276	RARA	P45983	MAPK8	T181	P182S	182	Missense	proximal	1	no	7.395	-0.333	EPSD;PhosphoSitePlus	COSMIC	2.638	Loss
CMGC_MAPK_JNK_MAPK8_ST	P10276	RARA	P45983	MAPK8	T181	P182T	182	Missense	proximal	1	no	7.395	0.409	EPSD;PhosphoSitePlus	COSMIC	2.638	Loss
CMGC_MAPK_JNK_MAPK8_ST	P10276	RARA	P45983	MAPK8	T181	P182L	182	Missense	proximal	1	no	7.395	-0.177	EPSD;PhosphoSitePlus	COSMIC	2.638	Loss
CMGC_MAPK_JNK_MAPK8_ST	P10276	RARA	P45983	MAPK8	T181	V184L	184	Missense	distal	3	no	7.395	7.377	EPSD;PhosphoSitePlus	COSMIC	2.638	Down-regulation
CMGC_MAPK_JNK_MAPK8_ST	P10276	RARA	P45983	MAPK8	T181	T181M	181	Missense	central	0	yes	7.395	0.000	EPSD;PhosphoSitePlus	COSMIC	2.638	Loss
CMGC_MAPK_JNK_MAPK8_ST	P10276	RARA	P45983	MAPK8	S445	P450F	450	Missense	distal	5	no	8.338	8.330	EPSD;PhosphoSitePlus	COSMIC	2.638	Down-regulation
CMGC_MAPK_JNK_MAPK8_ST	P10276	RARA	P45983	MAPK8	S445	P439S	439	Missense	distal	-6	no	8.338	8.249	EPSD;PhosphoSitePlus	COSMIC;CCLE	2.638	Down-regulation
CMGC_MAPK_JNK_MAPK8_ST	P10276	RARA	P45983	MAPK8	S445	G442C	442	Missense	distal	-3	no	8.338	8.364	EPSD;PhosphoSitePlus	COSMIC	2.638	Up-regulation
CMGC_MAPK_JNK_MAPK8_ST	P10276	RARA	P45983	MAPK8	S445	A438P	438	Missense	distal	-7	no	8.338	8.343	EPSD;PhosphoSitePlus	COSMIC	2.638	Up-regulation
CMGC_MAPK_JNK_MAPK8_ST	P10276	RARA	P45983	MAPK8	S445	P439L	439	Missense	distal	-6	no	8.338	8.429	EPSD;PhosphoSitePlus	COSMIC	2.638	Up-regulation
CMGC_MAPK_JNK_MAPK8_ST	P10276	RARA	P45983	MAPK8	S445	S452F	452	Missense	distal	7	no	8.338	8.413	EPSD;PhosphoSitePlus	COSMIC	2.638	Up-regulation
CMGC_MAPK_JNK_MAPK8_ST	P10276	RARA	P45983	MAPK8	S445	S447F	447	Missense	proximal	2	no	8.338	8.066	EPSD;PhosphoSitePlus	COSMIC	2.638	Down-regulation
CMGC_MAPK_JNK_MAPK8_ST	P10276	RARA	P45983	MAPK8	S445	S451R	451	Missense	distal	6	no	8.338	8.278	EPSD;PhosphoSitePlus	COSMIC	2.638	Down-regulation
CMGC_MAPK_JNK_MAPK8_ST	P10276	RARA	P45983	MAPK8	S449	P450F	450	Missense	proximal	1	no	8.147	-0.026	EPSD	COSMIC	2.638	Loss
CMGC_MAPK_JNK_MAPK8_ST	P10276	RARA	P45983	MAPK8	S449	G442C	442	Missense	distal	-7	no	8.147	8.145	EPSD	COSMIC	2.638	Down-regulation
CMGC_MAPK_JNK_MAPK8_ST	P10276	RARA	P45983	MAPK8	S449	R454K	454	Missense	distal	5	no	8.147	8.056	EPSD	COSMIC	2.638	Down-regulation
CMGC_MAPK_JNK_MAPK8_ST	P10276	RARA	P45983	MAPK8	S449	S452F	452	Missense	distal	3	no	8.147	8.366	EPSD	COSMIC	2.638	Up-regulation
CMGC_MAPK_JNK_MAPK8_ST	P10276	RARA	P45983	MAPK8	S449	S456R	456	Missense	distal	7	no	8.147	8.210	EPSD	COSMIC;CCLE	2.638	Up-regulation
CMGC_MAPK_JNK_MAPK8_ST	P10276	RARA	P45983	MAPK8	S449	S447F	447	Missense	proximal	-2	no	8.147	8.032	EPSD	COSMIC	2.638	Down-regulation
CMGC_MAPK_JNK_MAPK8_ST	P10276	RARA	P45983	MAPK8	S449	S451R	451	Missense	proximal	2	no	8.147	7.905	EPSD	COSMIC	2.638	Down-regulation
CMGC_MAPK_JNK_MAPK8_ST	P10276	RARA	P45983	MAPK8	S449	S456C	456	Missense	distal	7	no	8.147	8.199	EPSD	COSMIC	2.638	Up-regulation
CMGC_MAPK_JNK_MAPK8_ST	P10276	RARA	P45983	MAPK8	S456	P450F	450	Missense	distal	-6	no	7.771	7.863	EPSD	COSMIC	2.638	Up-regulation
CMGC_MAPK_JNK_MAPK8_ST	P10276	RARA	P45983	MAPK8	S456	S461C	461	Missense	distal	5	no	7.771	7.825	EPSD	COSMIC	2.638	Up-regulation
CMGC_MAPK_JNK_MAPK8_ST	P10276	RARA	P45983	MAPK8	S456	R454K	454	Missense	proximal	-2	no	7.771	7.880	EPSD	COSMIC	2.638	Up-regulation
CMGC_MAPK_JNK_MAPK8_ST	P10276	RARA	P45983	MAPK8	S456	P457L	457	Missense	proximal	1	no	7.771	0.198	EPSD	COSMIC	2.638	Loss
CMGC_MAPK_JNK_MAPK8_ST	P10276	RARA	P45983	MAPK8	S456	S452F	452	Missense	distal	-4	no	7.771	6.833	EPSD	COSMIC	2.638	Down-regulation
CMGC_MAPK_JNK_MAPK8_ST	P10276	RARA	P45983	MAPK8	S456	A458S	458	Missense	proximal	2	no	7.771	7.747	EPSD	COSMIC;CCLE	2.638	Down-regulation
CMGC_MAPK_JNK_MAPK8_ST	P10276	RARA	P45983	MAPK8	S456	S456R	456	Missense	central	0	yes	7.771	0.000	EPSD	COSMIC;CCLE	2.638	Loss
CMGC_MAPK_JNK_MAPK8_ST	P10276	RARA	P45983	MAPK8	S456	S451R	451	Missense	distal	-5	no	7.771	8.175	EPSD	COSMIC	2.638	Up-regulation
CMGC_MAPK_JNK_MAPK8_ST	P10276	RARA	P45983	MAPK8	S456	P457S	457	Missense	proximal	1	no	7.771	0.042	EPSD	COSMIC	2.638	Loss
CMGC_MAPK_JNK_MAPK8_ST	P10276	RARA	P45983	MAPK8	S456	S456C	456	Missense	central	0	yes	7.771	0.000	EPSD	COSMIC	2.638	Loss
CMGC_MAPK_JNK_MAPK8_ST	P10276	RARA	P45983	MAPK8	S461	S461C	461	Missense	central	0	yes	7.549	0.000	PhosphoSitePlus;EPSD	COSMIC	2.638	Loss
CMGC_MAPK_JNK_MAPK8_ST	P10276	RARA	P45983	MAPK8	S461	R454K	454	Missense	distal	-7	no	7.549	7.532	PhosphoSitePlus;EPSD	COSMIC	2.638	Down-regulation
CMGC_MAPK_JNK_MAPK8_ST	P10276	RARA	P45983	MAPK8	S461	P457L	457	Missense	distal	-4	no	7.549	7.222	PhosphoSitePlus;EPSD	COSMIC	2.638	Down-regulation
CMGC_MAPK_JNK_MAPK8_ST	P10276	RARA	P45983	MAPK8	S461	A458S	458	Missense	distal	-3	no	7.549	7.514	PhosphoSitePlus;EPSD	COSMIC;CCLE	2.638	Down-regulation
CMGC_MAPK_JNK_MAPK8_ST	P10276	RARA	P45983	MAPK8	S461	S456R	456	Missense	distal	-5	no	7.549	7.953	PhosphoSitePlus;EPSD	COSMIC;CCLE	2.638	Up-regulation
CMGC_MAPK_JNK_MAPK8_ST	P10276	RARA	P45983	MAPK8	S461	P457S	457	Missense	distal	-4	no	7.549	8.214	PhosphoSitePlus;EPSD	COSMIC	2.638	Up-regulation
CMGC_MAPK_JNK_MAPK8_ST	P10276	RARA	P45983	MAPK8	S461	S456C	456	Missense	distal	-5	no	7.549	7.854	PhosphoSitePlus;EPSD	COSMIC	2.638	Up-regulation
CMGC_MAPK_JNK_MAPK8_ST	O43521	BCL2L11	P45983	MAPK8	S59	P60S	60	Missense	proximal	1	no	8.407	0.679	EPSD	COSMIC	2.638	Loss
CMGC_MAPK_JNK_MAPK8_ST	O43521	BCL2L11	P45983	MAPK8	S59	P66S	66	Missense	distal	7	no	8.407	8.369	EPSD	COSMIC	2.638	Down-regulation
CMGC_MAPK_JNK_MAPK8_ST	O43521	BCL2L11	P45983	MAPK8	S59	G58S	58	Missense	proximal	-1	no	8.407	8.432	EPSD	COSMIC	2.638	Up-regulation
CMGC_MAPK_JNK_MAPK8_ST	O43521	BCL2L11	P45983	MAPK8	S69	P66S	66	Missense	distal	-3	no	7.830	7.992	EPSD	COSMIC	2.638	Up-regulation
CMGC_MAPK_JNK_MAPK8_ST	O43521	BCL2L11	P45983	MAPK8	S69	A74V	74	Missense	distal	5	no	7.830	7.903	EPSD	COSMIC	2.638	Up-regulation
CMGC_MAPK_JNK_MAPK8_ST	O43521	BCL2L11	P45983	MAPK8	S69	P72S	72	Missense	distal	3	no	7.830	7.704	EPSD	COSMIC	2.638	Down-regulation
CMGC_MAPK_JNK_MAPK8_ST	O43521	BCL2L11	P45983	MAPK8	S69	R76K	76	Missense	distal	7	no	7.830	7.752	EPSD	COSMIC	2.638	Down-regulation
CMGC_MAPK_JNK_MAPK8_ST	O43521	BCL2L11	P45983	MAPK8	S69	R76S	76	Missense	distal	7	no	7.830	7.767	EPSD	COSMIC	2.638	Down-regulation
CMGC_MAPK_JNK_MAPK8_ST	O43521	BCL2L11	P45983	MAPK8	S77	P78S	78	Missense	proximal	1	no	6.762	-0.967	EPSD	COSMIC	2.638	Loss
CMGC_MAPK_JNK_MAPK8_ST	O43521	BCL2L11	P45983	MAPK8	S77	A74V	74	Missense	distal	-3	no	6.762	6.333	EPSD	COSMIC	2.638	Down-regulation
CMGC_MAPK_JNK_MAPK8_ST	O43521	BCL2L11	P45983	MAPK8	S77	P72S	72	Missense	distal	-5	no	6.762	6.650	EPSD	COSMIC	2.638	Down-regulation
CMGC_MAPK_JNK_MAPK8_ST	O43521	BCL2L11	P45983	MAPK8	S77	R76K	76	Missense	proximal	-1	no	6.762	6.794	EPSD	COSMIC	2.638	Up-regulation
CMGC_MAPK_JNK_MAPK8_ST	O43521	BCL2L11	P45983	MAPK8	S77	R84K	84	Missense	distal	7	no	6.762	6.684	EPSD	COSMIC	2.638	Down-regulation
CMGC_MAPK_JNK_MAPK8_ST	O43521	BCL2L11	P45983	MAPK8	S77	R76S	76	Missense	proximal	-1	no	6.762	6.787	EPSD	COSMIC	2.638	Up-regulation
CMGC_MAPK_JNK_MAPK8_ST	O43521	BCL2L11	P45983	MAPK8	S77	P78L	78	Missense	proximal	1	no	6.762	-0.811	EPSD	COSMIC;GDSC;CCLE	2.638	Loss
CMGC_MAPK_JNK_MAPK8_ST	O43521	BCL2L11	P45983	MAPK8	S104	A106S	106	Missense	proximal	2	no	9.184	9.160	EPSD	COSMIC	2.638	Down-regulation
CMGC_MAPK_JNK_MAPK8_ST	O43521	BCL2L11	P45983	MAPK8	S104	S104R	104	Missense	central	0	yes	9.184	0.000	EPSD	COSMIC	2.638	Loss
CMGC_MAPK_JNK_MAPK8_ST	O43521	BCL2L11	P45983	MAPK8	S104	F97L	97	Missense	distal	-7	no	9.184	9.186	EPSD	COSMIC	2.638	Up-regulation
CMGC_MAPK_JNK_MAPK8_ST	O43521	BCL2L11	P45983	MAPK8	S104	D100G	100	Missense	distal	-4	no	9.184	8.862	EPSD	COSMIC	2.638	Down-regulation
CMGC_MAPK_JNK_MAPK8_ST	O43521	BCL2L11	P45983	MAPK8	T116	P120S	120	Missense	distal	4	no	8.491	8.516	EPSD	COSMIC	2.638	Up-regulation
CMGC_MAPK_JNK_MAPK8_ST	O43521	BCL2L11	P45983	MAPK8	S118	P120S	120	Missense	proximal	2	no	9.230	9.415	EPSD	COSMIC	2.638	Up-regulation
CMGC_MAPK_JNK_MAPK8_ST	P38936	CDKN1A	P45983	MAPK8	T57	D62Y	62	Missense	distal	5	no	6.619	6.680	EPSD;PhosphoSitePlus	COSMIC	2.638	Up-regulation
CMGC_MAPK_JNK_MAPK8_ST	P38936	CDKN1A	P45983	MAPK8	T57	D62H	62	Missense	distal	5	no	6.619	6.623	EPSD;PhosphoSitePlus	COSMIC	2.638	Up-regulation
CMGC_MAPK_JNK_MAPK8_ST	P38936	CDKN1A	P45983	MAPK8	T57	D52V	52	Missense	distal	-5	no	6.619	6.919	EPSD;PhosphoSitePlus	COSMIC	2.638	Up-regulation
CMGC_MAPK_JNK_MAPK8_ST	P38936	CDKN1A	P45983	MAPK8	T57	T57R	57	Missense	central	0	yes	6.619	0.000	EPSD;PhosphoSitePlus	COSMIC	2.638	Loss
CMGC_MAPK_JNK_MAPK8_ST	P38936	CDKN1A	P45983	MAPK8	S98	T97I	97	Missense	proximal	-1	no	8.346	8.333	EPSD;PhosphoSitePlus	COSMIC	2.638	Down-regulation
CMGC_MAPK_JNK_MAPK8_ST	P38936	CDKN1A	P45983	MAPK8	S130	E125Q	125	Missense	distal	-5	no	9.199	9.306	PhosphoSitePlus;EPSD	COSMIC	2.638	Up-regulation
CMGC_MAPK_JNK_MAPK8_ST	P38936	CDKN1A	P45983	MAPK8	S130	S137T	137	Missense	distal	7	no	9.199	9.207	PhosphoSitePlus;EPSD	COSMIC	2.638	Up-regulation
CMGC_MAPK_JNK_MAPK8_ST	P54259	ATN1	P45983	MAPK8	S34	P35L	35	Missense	proximal	1	no	6.566	-1.006	EPSD	COSMIC	2.638	Loss
CMGC_MAPK_JNK_MAPK8_ST	P54259	ATN1	P45983	MAPK8	S34	G31D	31	Missense	distal	-3	no	6.566	6.660	EPSD	COSMIC	2.638	Up-regulation
CMGC_MAPK_JNK_MAPK8_ST	P54259	ATN1	P45983	MAPK8	S43	S42R	42	Missense	proximal	-1	no	3.082	3.056	EPSD	COSMIC	2.638	Down-regulation
CMGC_MAPK_JNK_MAPK8_ST	P54259	ATN1	P45983	MAPK8	S101	D104N	104	Missense	distal	3	no	7.580	7.664	EPSD	COSMIC	2.638	Up-regulation
CMGC_MAPK_JNK_MAPK8_ST	P54259	ATN1	P45983	MAPK8	S132	I135F	135	Missense	distal	3	no	6.797	6.892	EPSD	COSMIC	2.638	Up-regulation
CMGC_MAPK_JNK_MAPK8_ST	P54259	ATN1	P45983	MAPK8	S134	I135F	135	Missense	proximal	1	no	3.767	1.469	EPSD	COSMIC	2.638	Loss
CMGC_MAPK_JNK_MAPK8_ST	P54259	ATN1	P45983	MAPK8	S137	I135F	135	Missense	proximal	-2	no	7.571	7.455	EPSD	COSMIC	2.638	Down-regulation
CMGC_MAPK_JNK_MAPK8_ST	P54259	ATN1	P45983	MAPK8	S168	P161L	161	Missense	distal	-7	no	7.914	7.926	EPSD	COSMIC	2.638	Up-regulation
CMGC_MAPK_JNK_MAPK8_ST	P54259	ATN1	P45983	MAPK8	S174	R177Q	177	Missense	distal	3	no	2.737	2.611	EPSD	COSMIC;GDSC	2.638	Loss
CMGC_MAPK_JNK_MAPK8_ST	P54259	ATN1	P45983	MAPK8	T175	S182N	182	Missense	distal	7	no	7.233	7.302	EPSD	COSMIC	2.638	Up-regulation
CMGC_MAPK_JNK_MAPK8_ST	P54259	ATN1	P45983	MAPK8	T175	R177Q	177	Missense	proximal	2	no	7.233	7.408	EPSD	COSMIC;GDSC	2.638	Up-regulation
CMGC_MAPK_JNK_MAPK8_ST	P54259	ATN1	P45983	MAPK8	T190	S188F	188	Missense	proximal	-2	no	7.003	6.888	EPSD	COSMIC	2.638	Down-regulation
CMGC_MAPK_JNK_MAPK8_ST	P54259	ATN1	P45983	MAPK8	T190	P197S	197	Missense	distal	7	no	7.003	6.964	EPSD	COSMIC	2.638	Down-regulation
CMGC_MAPK_JNK_MAPK8_ST	P54259	ATN1	P45983	MAPK8	T190	E184D	184	Missense	distal	-6	no	7.003	7.103	EPSD	COSMIC	2.638	Up-regulation
CMGC_MAPK_JNK_MAPK8_ST	P54259	ATN1	P45983	MAPK8	T190	G193E	193	Missense	distal	3	no	7.003	6.825	EPSD	COSMIC	2.638	Down-regulation
CMGC_MAPK_JNK_MAPK8_ST	P54259	ATN1	P45983	MAPK8	S645	G640V	640	Missense	distal	-5	no	8.385	8.534	EPSD	COSMIC	2.638	Up-regulation
CMGC_MAPK_JNK_MAPK8_ST	P54259	ATN1	P45983	MAPK8	S645	G647E	647	Missense	proximal	2	no	8.385	8.651	EPSD	COSMIC	2.638	Up-regulation
CMGC_MAPK_JNK_MAPK8_ST	P54259	ATN1	P45983	MAPK8	T653	P655S	655	Missense	proximal	2	no	6.419	6.604	EPSD	COSMIC	2.638	Up-regulation
CMGC_MAPK_JNK_MAPK8_ST	P54259	ATN1	P45983	MAPK8	T653	G647E	647	Missense	distal	-6	no	6.419	6.261	EPSD	COSMIC	2.638	Down-regulation
CMGC_MAPK_JNK_MAPK8_ST	P54259	ATN1	P45983	MAPK8	S661	P655S	655	Missense	distal	-6	no	6.344	6.255	EPSD	COSMIC	2.638	Down-regulation
CMGC_MAPK_JNK_MAPK8_ST	P54259	ATN1	P45983	MAPK8	S689	T691I	691	Missense	proximal	2	no	8.420	8.295	EPSD	COSMIC	2.638	Down-regulation
CMGC_MAPK_JNK_MAPK8_ST	P54259	ATN1	P45983	MAPK8	T736	A731S	731	Missense	distal	-5	no	8.692	8.709	EPSD	COSMIC	2.638	Up-regulation
CMGC_MAPK_JNK_MAPK8_ST	P22736	NR4A1	P45983	MAPK8	T10	A6T	6	Missense	distal	-4	no	8.351	8.314	EPSD	COSMIC;GDSC;CCLE	2.638	Down-regulation
CMGC_MAPK_JNK_MAPK8_ST	P22736	NR4A1	P45983	MAPK8	T10	P13L	13	Missense	distal	3	no	8.351	8.453	EPSD	COSMIC	2.638	Up-regulation
CMGC_MAPK_JNK_MAPK8_ST	P22736	NR4A1	P45983	MAPK8	T10	G9W	9	Missense	proximal	-1	no	8.351	8.346	EPSD	COSMIC	2.638	Down-regulation
CMGC_MAPK_JNK_MAPK8_ST	P22736	NR4A1	P45983	MAPK8	S14	P13L	13	Missense	proximal	-1	no	7.779	7.761	EPSD	COSMIC	2.638	Down-regulation
CMGC_MAPK_JNK_MAPK8_ST	P22736	NR4A1	P45983	MAPK8	S14	R18C	18	Missense	distal	4	no	7.779	7.813	EPSD	COSMIC	2.638	Up-regulation
CMGC_MAPK_JNK_MAPK8_ST	P22736	NR4A1	P45983	MAPK8	S14	G9W	9	Missense	distal	-5	no	7.779	7.853	EPSD	COSMIC	2.638	Up-regulation
CMGC_MAPK_JNK_MAPK8_ST	P22736	NR4A1	P45983	MAPK8	S95	T88A	88	Missense	distal	-7	no	8.503	8.502	PhosphoSitePlus	COSMIC	2.638	Down-regulation
CMGC_MAPK_JNK_MAPK8_ST	P22736	NR4A1	P45983	MAPK8	S95	S98P	98	Missense	distal	3	no	8.503	8.629	PhosphoSitePlus	COSMIC	2.638	Up-regulation
CMGC_MAPK_JNK_MAPK8_ST	P22736	NR4A1	P45983	MAPK8	S140	S137L	137	Missense	distal	-3	no	8.612	8.271	EPSD	COSMIC	2.638	Down-regulation
CMGC_MAPK_JNK_MAPK8_ST	P22736	NR4A1	P45983	MAPK8	S140	P135S	135	Missense	distal	-5	no	8.612	8.500	EPSD	COSMIC	2.638	Down-regulation
CMGC_MAPK_JNK_MAPK8_ST	P22736	NR4A1	P45983	MAPK8	S140	F146C	146	Missense	distal	6	no	8.612	8.632	EPSD	COSMIC	2.638	Up-regulation
CMGC_MAPK_JNK_MAPK8_ST	P22736	NR4A1	P45983	MAPK8	S140	P139L	139	Missense	proximal	-1	no	8.612	8.593	EPSD	COSMIC	2.638	Down-regulation
CMGC_MAPK_JNK_MAPK8_ST	P22736	NR4A1	P45983	MAPK8	S140	S142F	142	Missense	proximal	2	no	8.612	8.340	EPSD	COSMIC	2.638	Down-regulation
CMGC_MAPK_JNK_MAPK8_ST	P22736	NR4A1	P45983	MAPK8	T143	P148S	148	Missense	distal	5	no	7.362	7.279	EPSD	COSMIC	2.638	Down-regulation
CMGC_MAPK_JNK_MAPK8_ST	P22736	NR4A1	P45983	MAPK8	T143	S137L	137	Missense	distal	-6	no	7.362	7.542	EPSD	COSMIC	2.638	Up-regulation
CMGC_MAPK_JNK_MAPK8_ST	P22736	NR4A1	P45983	MAPK8	T143	F146C	146	Missense	distal	3	no	7.362	7.308	EPSD	COSMIC	2.638	Down-regulation
CMGC_MAPK_JNK_MAPK8_ST	P22736	NR4A1	P45983	MAPK8	T143	P139L	139	Missense	distal	-4	no	7.362	7.036	EPSD	COSMIC	2.638	Down-regulation
CMGC_MAPK_JNK_MAPK8_ST	P22736	NR4A1	P45983	MAPK8	T143	S142F	142	Missense	proximal	-1	no	7.362	7.333	EPSD	COSMIC	2.638	Down-regulation
CMGC_MAPK_JNK_MAPK8_ST	P22736	NR4A1	P45983	MAPK8	S152	P148S	148	Missense	distal	-4	no	7.205	7.870	EPSD	COSMIC	2.638	Up-regulation
CMGC_MAPK_JNK_MAPK8_ST	P22736	NR4A1	P45983	MAPK8	S152	S152P	152	Missense	central	0	yes	7.205	0.000	EPSD	COSMIC	2.638	Loss
CMGC_MAPK_JNK_MAPK8_ST	P22736	NR4A1	P45983	MAPK8	S152	F146C	146	Missense	distal	-6	no	7.205	7.154	EPSD	COSMIC	2.638	Down-regulation
CMGC_MAPK_JNK_MAPK8_ST	P22736	NR4A1	P45983	MAPK8	S152	S157F	157	Missense	distal	5	no	7.205	7.281	EPSD	COSMIC	2.638	Up-regulation
CMGC_MAPK_JNK_MAPK8_ST	P22736	NR4A1	P45983	MAPK8	S152	G159S	159	Missense	distal	7	no	7.205	7.140	EPSD	COSMIC	2.638	Down-regulation
CMGC_MAPK_JNK_MAPK8_ST	P22736	NR4A1	P45983	MAPK8	S193	P200S	200	Missense	distal	7	no	6.497	6.459	EPSD	COSMIC	2.638	Down-regulation
CMGC_MAPK_JNK_MAPK8_ST	P22736	NR4A1	P45983	MAPK8	S193	S191L	191	Missense	proximal	-2	no	6.497	6.410	EPSD	COSMIC	2.638	Down-regulation
CMGC_MAPK_JNK_MAPK8_ST	P22736	NR4A1	P45983	MAPK8	S193	S191W	191	Missense	proximal	-2	no	6.497	6.425	EPSD	COSMIC	2.638	Down-regulation
CMGC_MAPK_JNK_MAPK8_ST	P22736	NR4A1	P45983	MAPK8	S193	S191F	191	Missense	proximal	-2	no	6.497	6.382	EPSD	COSMIC	2.638	Down-regulation
CMGC_MAPK_JNK_MAPK8_ST	P22736	NR4A1	P45983	MAPK8	S193	P187S	187	Missense	distal	-6	no	6.497	6.408	EPSD	COSMIC	2.638	Down-regulation
CMGC_MAPK_JNK_MAPK8_ST	P22736	NR4A1	P45983	MAPK8	S193	P200L	200	Missense	distal	7	no	6.497	6.537	EPSD	COSMIC	2.638	Up-regulation
CMGC_MAPK_JNK_MAPK8_ST	P22736	NR4A1	P45983	MAPK8	S193	P198R	198	Missense	distal	5	no	6.497	6.486	EPSD	COSMIC;GDSC;CCLE	2.638	Down-regulation
CMGC_MAPK_JNK_MAPK8_ST	P22736	NR4A1	P45983	MAPK8	S199	P200S	200	Missense	proximal	1	no	8.422	0.694	EPSD	COSMIC	2.638	Loss
CMGC_MAPK_JNK_MAPK8_ST	P22736	NR4A1	P45983	MAPK8	S199	S201R	201	Missense	proximal	2	no	8.422	8.181	EPSD	COSMIC	2.638	Down-regulation
CMGC_MAPK_JNK_MAPK8_ST	P22736	NR4A1	P45983	MAPK8	S199	P200L	200	Missense	proximal	1	no	8.422	0.850	EPSD	COSMIC	2.638	Loss
CMGC_MAPK_JNK_MAPK8_ST	P22736	NR4A1	P45983	MAPK8	S199	P198R	198	Missense	proximal	-1	no	8.422	8.407	EPSD	COSMIC;GDSC;CCLE	2.638	Down-regulation
CMGC_MAPK_JNK_MAPK8_ST	P22736	NR4A1	P45983	MAPK8	S205	P211R	211	Missense	distal	6	no	7.038	7.002	EPSD	COSMIC	2.638	Down-regulation
CMGC_MAPK_JNK_MAPK8_ST	P22736	NR4A1	P45983	MAPK8	S205	P200S	200	Missense	distal	-5	no	7.038	6.926	EPSD	COSMIC	2.638	Down-regulation
CMGC_MAPK_JNK_MAPK8_ST	P22736	NR4A1	P45983	MAPK8	S205	S201R	201	Missense	distal	-4	no	7.038	6.236	EPSD	COSMIC	2.638	Down-regulation
CMGC_MAPK_JNK_MAPK8_ST	P22736	NR4A1	P45983	MAPK8	S205	P200L	200	Missense	distal	-5	no	7.038	7.398	EPSD	COSMIC	2.638	Up-regulation
CMGC_MAPK_JNK_MAPK8_ST	P22736	NR4A1	P45983	MAPK8	S205	P198R	198	Missense	distal	-7	no	7.038	7.045	EPSD	COSMIC;GDSC;CCLE	2.638	Up-regulation
CMGC_MAPK_JNK_MAPK8_ST	P22736	NR4A1	P45983	MAPK8	S237	P235L	235	Missense	proximal	-2	no	7.804	7.611	EPSD	COSMIC	2.638	Down-regulation
CMGC_MAPK_JNK_MAPK8_ST	P22736	NR4A1	P45983	MAPK8	S237	E241G	241	Missense	distal	4	no	7.804	7.511	EPSD	COSMIC	2.638	Down-regulation
CMGC_MAPK_JNK_MAPK8_ST	P22736	NR4A1	P45983	MAPK8	S257	G258W	258	Missense	proximal	1	no	1.514	2.778	EPSD	COSMIC	2.638	Gain
CMGC_MAPK_JNK_MAPK8_ST	P22736	NR4A1	P45983	MAPK8	S360	P361S	361	Missense	proximal	1	no	7.129	-0.599	EPSD	COSMIC	2.638	Loss
CMGC_MAPK_JNK_MAPK8_ST	P22736	NR4A1	P45983	MAPK8	S360	P353L	353	Missense	distal	-7	no	7.129	7.141	EPSD	COSMIC	2.638	Up-regulation
CMGC_MAPK_JNK_MAPK8_ST	P22736	NR4A1	P45983	MAPK8	S360	P357L	357	Missense	distal	-3	no	7.129	6.950	EPSD	COSMIC	2.638	Down-regulation
CMGC_MAPK_JNK_MAPK8_ST	P22736	NR4A1	P45983	MAPK8	S360	A359S	359	Missense	proximal	-1	no	7.129	7.128	EPSD	COSMIC	2.638	Down-regulation
CMGC_MAPK_JNK_MAPK8_ST	P22736	NR4A1	P45983	MAPK8	S360	L364I	364	Missense	distal	4	no	7.129	7.372	EPSD	COSMIC	2.638	Up-regulation
CMGC_MAPK_JNK_MAPK8_ST	P22736	NR4A1	P45983	MAPK8	S360	A362V	362	Missense	proximal	2	no	7.129	6.812	EPSD	COSMIC	2.638	Down-regulation
CMGC_MAPK_JNK_MAPK8_ST	P22736	NR4A1	P45983	MAPK8	S360	A359D	359	Missense	proximal	-1	no	7.129	7.114	EPSD	COSMIC	2.638	Down-regulation
CMGC_MAPK_JNK_MAPK8_ST	P22736	NR4A1	P45983	MAPK8	S431	P432L	432	Missense	proximal	1	no	7.530	-0.043	EPSD	COSMIC	2.638	Loss
CMGC_MAPK_JNK_MAPK8_ST	P22736	NR4A1	P45983	MAPK8	S431	A433T	433	Missense	proximal	2	no	7.530	7.509	EPSD	COSMIC	2.638	Down-regulation
CMGC_MAPK_JNK_MAPK8_ST	Q6SZW1	SARM1	P45983	MAPK8	S54	E52G	52	Missense	proximal	-2	no	7.357	7.259	EPSD	COSMIC	2.638	Down-regulation
CMGC_MAPK_JNK_MAPK8_ST	Q6SZW1	SARM1	P45983	MAPK8	S54	R51P	51	Missense	distal	-3	no	7.357	7.500	EPSD	COSMIC	2.638	Up-regulation
CMGC_MAPK_JNK_MAPK8_ST	P19793	RXRA	P45983	MAPK8	S49	P50S	50	Missense	proximal	1	no	7.546	-0.182	EPSD	COSMIC;GDSC;CCLE	2.638	Loss
CMGC_MAPK_JNK_MAPK8_ST	P19793	RXRA	P45983	MAPK8	T82	G86C	86	Missense	distal	4	no	9.219	9.231	EPSD	COSMIC	2.638	Up-regulation
CMGC_MAPK_JNK_MAPK8_ST	P19793	RXRA	P45983	MAPK8	S225	D229G	229	Missense	distal	4	no	4.684	4.542	EPSD	COSMIC	2.638	Down-regulation
CMGC_MAPK_JNK_MAPK8_ST	P19793	RXRA	P45983	MAPK8	S225	S222L	222	Missense	distal	-3	no	4.684	4.343	EPSD	COSMIC	2.638	Down-regulation
CMGC_MAPK_JNK_MAPK8_ST	P19793	RXRA	P45983	MAPK8	S260	M254I	254	Missense	distal	-6	no	7.538	7.468	PhosphoSitePlus	COSMIC	2.638	Down-regulation
CMGC_MAPK_JNK_MAPK8_ST	O43379	WDR62	P45983	MAPK8	S120	D122G	122	Missense	proximal	2	no	7.127	7.061	EPSD	COSMIC	2.638	Down-regulation
CMGC_MAPK_JNK_MAPK8_ST	O43379	WDR62	P45983	MAPK8	S120	A116V	116	Missense	distal	-4	no	7.127	6.271	EPSD	COSMIC	2.638	Down-regulation
CMGC_MAPK_JNK_MAPK8_ST	O43379	WDR62	P45983	MAPK8	S164	A162T	162	Missense	proximal	-2	no	7.537	7.507	EPSD	COSMIC	2.638	Down-regulation
CMGC_MAPK_JNK_MAPK8_ST	O43379	WDR62	P45983	MAPK8	S211	F206L	206	Missense	distal	-5	no	3.339	3.342	EPSD	COSMIC	2.638	Up-regulation
CMGC_MAPK_JNK_MAPK8_ST	O43379	WDR62	P45983	MAPK8	S211	L204H	204	Missense	distal	-7	no	3.339	3.333	EPSD	COSMIC	2.638	Down-regulation
CMGC_MAPK_JNK_MAPK8_ST	O43379	WDR62	P45983	MAPK8	T814	P808L	808	Missense	distal	-6	no	6.072	6.163	EPSD	COSMIC	2.638	Up-regulation
CMGC_MAPK_JNK_MAPK8_ST	O43379	WDR62	P45983	MAPK8	S974	Q971H	971	Missense	distal	-3	no	3.174	3.012	EPSD	COSMIC	2.638	Down-regulation
CMGC_MAPK_JNK_MAPK8_ST	O43379	WDR62	P45983	MAPK8	S982	P988R	988	Missense	distal	6	no	8.302	8.267	EPSD	COSMIC	2.638	Down-regulation
CMGC_MAPK_JNK_MAPK8_ST	O43379	WDR62	P45983	MAPK8	S987	E994Q	994	Missense	distal	7	no	6.571	6.588	EPSD	COSMIC	2.638	Up-regulation
CMGC_MAPK_JNK_MAPK8_ST	O43379	WDR62	P45983	MAPK8	S987	P988R	988	Missense	proximal	1	no	6.571	-0.565	EPSD	COSMIC	2.638	Loss
CMGC_MAPK_JNK_MAPK8_ST	O43379	WDR62	P45983	MAPK8	T1053	P1054S	1054	Missense	proximal	1	no	7.656	-0.072	PhosphoSitePlus	COSMIC	2.638	Loss
CMGC_MAPK_JNK_MAPK8_ST	O43379	WDR62	P45983	MAPK8	T1053	P1054L	1054	Missense	proximal	1	no	7.656	0.084	PhosphoSitePlus	COSMIC	2.638	Loss
CMGC_MAPK_JNK_MAPK8_ST	O43379	WDR62	P45983	MAPK8	T1053	L1060I	1060	Missense	distal	7	no	7.656	7.618	PhosphoSitePlus	COSMIC	2.638	Down-regulation
CMGC_MAPK_JNK_MAPK8_ST	O43379	WDR62	P45983	MAPK8	S1123	E1125K	1125	Missense	proximal	2	no	7.213	7.231	EPSD	COSMIC	2.638	Up-regulation
CMGC_MAPK_JNK_MAPK8_ST	O43379	WDR62	P45983	MAPK8	T1191	D1186G	1186	Missense	distal	-5	no	6.360	6.511	EPSD	COSMIC	2.638	Up-regulation
CMGC_MAPK_JNK_MAPK8_ST	O43379	WDR62	P45983	MAPK8	T1191	P1198T	1198	Missense	distal	7	no	6.360	6.329	EPSD	COSMIC	2.638	Down-regulation
CMGC_MAPK_JNK_MAPK8_ST	O43379	WDR62	P45983	MAPK8	T1197	P1198T	1198	Missense	proximal	1	no	8.988	2.002	EPSD	COSMIC	2.638	Loss
CMGC_MAPK_JNK_MAPK8_ST	O43379	WDR62	P45983	MAPK8	T1265	A1266V	1266	Missense	proximal	1	no	2.899	0.502	EPSD	COSMIC	2.638	Loss
CMGC_MAPK_JNK_MAPK8_ST	O43379	WDR62	P45983	MAPK8	T1268	A1266V	1266	Missense	proximal	-2	no	8.334	8.144	EPSD	COSMIC	2.638	Down-regulation
CMGC_MAPK_JNK_MAPK8_ST	O43379	WDR62	P45983	MAPK8	T1268	G1275C	1275	Missense	distal	7	no	8.334	8.322	EPSD	COSMIC;CCLE	2.638	Down-regulation
CMGC_MAPK_JNK_MAPK8_ST	O43379	WDR62	P45983	MAPK8	S1325	A1318T	1318	Missense	distal	-7	no	7.336	7.337	EPSD	COSMIC	2.638	Up-regulation
CMGC_MAPK_JNK_MAPK8_ST	O43379	WDR62	P45983	MAPK8	S1325	P1322H	1322	Missense	distal	-3	no	7.336	7.231	EPSD	COSMIC	2.638	Down-regulation
CMGC_MAPK_JNK_MAPK8_ST	O43379	WDR62	P45983	MAPK8	S1325	A1323T	1323	Missense	proximal	-2	no	7.336	7.306	EPSD	COSMIC	2.638	Down-regulation
CMGC_MAPK_JNK_MAPK8_ST	O43379	WDR62	P45983	MAPK8	S1348	A1345S	1345	Missense	distal	-3	no	9.178	9.142	EPSD	COSMIC	2.638	Down-regulation
CMGC_MAPK_JNK_MAPK8_ST	O43379	WDR62	P45983	MAPK8	S1388	S1388N	1388	Missense	central	0	yes	6.389	0.000	EPSD	COSMIC	2.638	Loss
CMGC_MAPK_JNK_MAPK8_ST	O43379	WDR62	P45983	MAPK8	S1388	R1391C	1391	Missense	distal	3	no	6.389	6.371	EPSD	COSMIC	2.638	Down-regulation
CMGC_MAPK_JNK_MAPK8_ST	O43379	WDR62	P45983	MAPK8	S1388	S1393N	1393	Missense	distal	5	no	6.389	6.458	EPSD	COSMIC	2.638	Up-regulation
CMGC_MAPK_JNK_MAPK8_ST	O43379	WDR62	P45983	MAPK8	S1405	S1405P	1405	Missense	central	0	yes	7.398	0.000	EPSD	COSMIC	2.638	Loss
CMGC_MAPK_JNK_MAPK8_ST	O43379	WDR62	P45983	MAPK8	S1405	E1400K	1400	Missense	distal	-5	no	7.398	7.321	EPSD	COSMIC	2.638	Down-regulation
CMGC_MAPK_JNK_MAPK8_ST	P08047	SP1	P45983	MAPK8	S59	S59Y	59	Missense	central	0	yes	10.071	0.000	EPSD	COSMIC	2.638	Loss
CMGC_MAPK_JNK_MAPK8_ST	P08047	SP1	P45983	MAPK8	S73	E72K	72	Missense	proximal	-1	no	8.822	8.825	EPSD	COSMIC	2.638	Up-regulation
CMGC_MAPK_JNK_MAPK8_ST	P08047	SP1	P45983	MAPK8	S73	N79K	79	Missense	distal	6	no	8.822	8.905	EPSD	COSMIC	2.638	Up-regulation
CMGC_MAPK_JNK_MAPK8_ST	P08047	SP1	P45983	MAPK8	T90	A97V	97	Missense	distal	7	no	2.563	2.642	EPSD	COSMIC	2.638	Gain
CMGC_MAPK_JNK_MAPK8_ST	P08047	SP1	P45983	MAPK8	T90	P84L	84	Missense	distal	-6	no	2.563	2.654	EPSD	COSMIC	2.638	Gain
CMGC_MAPK_JNK_MAPK8_ST	P08047	SP1	P45983	MAPK8	T278	T278M	278	Missense	central	0	yes	8.327	0.000	PhosphoSitePlus;EPSD	COSMIC	2.638	Loss
CMGC_MAPK_JNK_MAPK8_ST	P08047	SP1	P45983	MAPK8	T453	P458H	458	Missense	distal	5	no	8.012	7.980	EPSD	COSMIC;GDSC;CCLE	2.638	Down-regulation
CMGC_MAPK_JNK_MAPK8_ST	P08047	SP1	P45983	MAPK8	T453	R452W	452	Missense	proximal	-1	no	8.012	8.008	EPSD	COSMIC	2.638	Down-regulation
CMGC_MAPK_JNK_MAPK8_ST	P08047	SP1	P45983	MAPK8	T737	T739P	739	Missense	proximal	2	no	2.815	2.627	EPSD	COSMIC	2.638	Loss
CMGC_MAPK_JNK_MAPK8_ST	P08047	SP1	P45983	MAPK8	T737	S732L	732	Missense	distal	-5	no	2.815	3.287	EPSD	COSMIC	2.638	Up-regulation
CMGC_MAPK_JNK_MAPK8_ST	P08047	SP1	P45983	MAPK8	T739	T739P	739	Missense	central	0	yes	9.677	0.000	EPSD;PhosphoSitePlus	COSMIC	2.638	Loss
CMGC_MAPK_JNK_MAPK8_ST	P08047	SP1	P45983	MAPK8	T739	T746P	746	Missense	distal	7	no	9.677	9.708	EPSD;PhosphoSitePlus	COSMIC	2.638	Up-regulation
CMGC_MAPK_JNK_MAPK8_ST	P08047	SP1	P45983	MAPK8	T739	S732L	732	Missense	distal	-7	no	9.677	9.695	EPSD;PhosphoSitePlus	COSMIC	2.638	Up-regulation
CMGC_MAPK_JNK_MAPK8_ST	P08047	SP1	P45983	MAPK8	T745	T746P	746	Missense	proximal	1	no	0.278	7.265	EPSD	COSMIC	2.638	Gain
CMGC_MAPK_JNK_MAPK8_ST	P49023	PXN	P45983	MAPK8	T29	P22L	22	Missense	distal	-7	no	6.499	6.510	EPSD	COSMIC	2.638	Up-regulation
CMGC_MAPK_JNK_MAPK8_ST	P49023	PXN	P45983	MAPK8	T29	P22H	22	Missense	distal	-7	no	6.499	6.505	EPSD	COSMIC;GDSC;CCLE	2.638	Up-regulation
CMGC_MAPK_JNK_MAPK8_ST	P49023	PXN	P45983	MAPK8	T29	P30L	30	Missense	proximal	1	no	6.499	-1.074	EPSD	COSMIC	2.638	Loss
CMGC_MAPK_JNK_MAPK8_ST	P49023	PXN	P45983	MAPK8	S85	S83N	83	Missense	proximal	-2	no	7.393	7.275	EPSD	COSMIC	2.638	Down-regulation
CMGC_MAPK_JNK_MAPK8_ST	P49023	PXN	P45983	MAPK8	S106	P107L	107	Missense	proximal	1	no	6.638	-0.934	EPSD	COSMIC;GDSC	2.638	Loss
CMGC_MAPK_JNK_MAPK8_ST	P49023	PXN	P45983	MAPK8	S106	P107Q	107	Missense	proximal	1	no	6.638	-0.471	EPSD	COSMIC	2.638	Loss
CMGC_MAPK_JNK_MAPK8_ST	P49023	PXN	P45983	MAPK8	S130	V133I	133	Missense	distal	3	no	8.678	8.556	EPSD	COSMIC	2.638	Down-regulation
CMGC_MAPK_JNK_MAPK8_ST	P49023	PXN	P45983	MAPK8	S130	A127T	127	Missense	distal	-3	no	8.678	8.625	EPSD	COSMIC	2.638	Down-regulation
CMGC_MAPK_JNK_MAPK8_ST	P49023	PXN	P45983	MAPK8	S130	T136M	136	Missense	distal	6	no	8.678	8.618	EPSD	COSMIC	2.638	Down-regulation
CMGC_MAPK_JNK_MAPK8_ST	P49023	PXN	P45983	MAPK8	S130	S126P	126	Missense	distal	-4	no	8.678	8.013	EPSD	COSMIC	2.638	Down-regulation
CMGC_MAPK_JNK_MAPK8_ST	P49023	PXN	P45983	MAPK8	T132	V133I	133	Missense	proximal	1	no	0.089	2.959	EPSD	COSMIC	2.638	Gain
CMGC_MAPK_JNK_MAPK8_ST	P49023	PXN	P45983	MAPK8	S170	D165Y	165	Missense	distal	-5	no	9.565	9.940	EPSD	COSMIC	2.638	Up-regulation
CMGC_MAPK_JNK_MAPK8_ST	P49023	PXN	P45983	MAPK8	S170	G175W	175	Missense	distal	5	no	9.565	9.590	EPSD	COSMIC	2.638	Up-regulation
CMGC_MAPK_JNK_MAPK8_ST	P49023	PXN	P45983	MAPK8	S170	P163L	163	Missense	distal	-7	no	9.565	9.576	EPSD	COSMIC	2.638	Up-regulation
CMGC_MAPK_JNK_MAPK8_ST	P49023	PXN	P45983	MAPK8	S170	P172L	172	Missense	proximal	2	no	9.565	9.488	EPSD	COSMIC	2.638	Down-regulation
CMGC_MAPK_JNK_MAPK8_ST	P49023	PXN	P45983	MAPK8	S170	P171S	171	Missense	proximal	1	no	9.565	1.836	EPSD	COSMIC	2.638	Loss
CMGC_MAPK_JNK_MAPK8_ST	P49023	PXN	P45983	MAPK8	S170	N168I	168	Missense	proximal	-2	no	9.565	9.684	EPSD	COSMIC;GDSC	2.638	Up-regulation
CMGC_MAPK_JNK_MAPK8_ST	P49023	PXN	P45983	MAPK8	S178	G175W	175	Missense	distal	-3	no	7.918	7.809	PhosphoSitePlus	COSMIC	2.638	Down-regulation
CMGC_MAPK_JNK_MAPK8_ST	P49023	PXN	P45983	MAPK8	S178	P172L	172	Missense	distal	-6	no	7.918	8.009	PhosphoSitePlus	COSMIC	2.638	Up-regulation
CMGC_MAPK_JNK_MAPK8_ST	P49023	PXN	P45983	MAPK8	S178	P171S	171	Missense	distal	-7	no	7.918	7.912	PhosphoSitePlus	COSMIC	2.638	Down-regulation
CMGC_MAPK_JNK_MAPK8_ST	P49023	PXN	P45983	MAPK8	S230	P231L	231	Missense	proximal	1	no	8.290	0.718	EPSD	COSMIC;CCLE	2.638	Loss
CMGC_MAPK_JNK_MAPK8_ST	P49023	PXN	P45983	MAPK8	S230	P229L	229	Missense	proximal	-1	no	8.290	8.271	EPSD	COSMIC	2.638	Down-regulation
CMGC_MAPK_JNK_MAPK8_ST	P49023	PXN	P45983	MAPK8	S244	E241D	241	Missense	distal	-3	no	8.587	8.348	EPSD	COSMIC	2.638	Down-regulation
CMGC_MAPK_JNK_MAPK8_ST	P49023	PXN	P45983	MAPK8	S303	P304L	304	Missense	proximal	1	no	7.429	-0.143	EPSD	COSMIC	2.638	Loss
CMGC_MAPK_JNK_MAPK8_ST	P49023	PXN	P45983	MAPK8	S303	P304R	304	Missense	proximal	1	no	7.429	0.293	EPSD	COSMIC	2.638	Loss
CMGC_MAPK_JNK_MAPK8_ST	P49023	PXN	P45983	MAPK8	S303	G300R	300	Missense	distal	-3	no	7.429	7.406	EPSD	COSMIC	2.638	Down-regulation
CMGC_MAPK_JNK_MAPK8_ST	P49023	PXN	P45983	MAPK8	S303	E309K	309	Missense	distal	6	no	7.429	7.445	EPSD	COSMIC	2.638	Up-regulation
CMGC_MAPK_JNK_MAPK8_ST	P49023	PXN	P45983	MAPK8	S303	D298Y	298	Missense	distal	-5	no	7.429	7.805	EPSD	COSMIC	2.638	Up-regulation
CMGC_MAPK_JNK_MAPK8_ST	P49023	PXN	P45983	MAPK8	S303	S303R	303	Missense	central	0	yes	7.429	0.000	EPSD	COSMIC	2.638	Loss
CMGC_MAPK_JNK_MAPK8_ST	P49023	PXN	P45983	MAPK8	S303	G306R	306	Missense	distal	3	no	7.429	7.422	EPSD	COSMIC	2.638	Down-regulation
CMGC_MAPK_JNK_MAPK8_ST	P49023	PXN	P45983	MAPK8	S303	R301Q	301	Missense	proximal	-2	no	7.429	7.503	EPSD	COSMIC	2.638	Up-regulation
CMGC_MAPK_JNK_MAPK8_ST	P49023	PXN	P45983	MAPK8	S303	G299S	299	Missense	distal	-4	no	7.429	8.318	EPSD	COSMIC	2.638	Up-regulation
CMGC_MAPK_JNK_MAPK8_ST	P49023	PXN	P45983	MAPK8	S321	P328S	328	Missense	distal	7	no	2.663	2.624	EPSD	COSMIC	2.638	Loss
CMGC_MAPK_JNK_MAPK8_ST	P49023	PXN	P45983	MAPK8	S321	S322A	322	Missense	proximal	1	no	2.663	4.044	EPSD	COSMIC	2.638	Up-regulation
CMGC_MAPK_JNK_MAPK8_ST	P49023	PXN	P45983	MAPK8	S322	P328S	328	Missense	distal	6	no	7.138	7.162	EPSD	COSMIC	2.638	Up-regulation
CMGC_MAPK_JNK_MAPK8_ST	P49023	PXN	P45983	MAPK8	S322	S322A	322	Missense	central	0	yes	7.138	0.000	EPSD	COSMIC	2.638	Loss
CMGC_MAPK_JNK_MAPK8_ST	P49023	PXN	P45983	MAPK8	S414	K407E	407	Missense	distal	-7	no	6.738	6.741	EPSD	COSMIC	2.638	Up-regulation
CMGC_MAPK_JNK_MAPK8_ST	P49023	PXN	P45983	MAPK8	S414	R416H	416	Missense	proximal	2	no	6.738	6.796	EPSD	COSMIC	2.638	Up-regulation
CMGC_MAPK_JNK_MAPK8_ST	P31947	SFN	P45983	MAPK8	S186	E182D	182	Missense	distal	-4	no	9.620	9.197	PhosphoSitePlus	COSMIC;CCLE	2.638	Down-regulation
CMGC_MAPK_JNK_MAPK8_ST	P31947	SFN	P45983	MAPK8	S186	A184T	184	Missense	proximal	-2	no	9.620	9.590	PhosphoSitePlus	COSMIC	2.638	Down-regulation
CMGC_MAPK_JNK_MAPK8_ST	P31947	SFN	P45983	MAPK8	S186	E188Q	188	Missense	proximal	2	no	9.620	9.490	PhosphoSitePlus	COSMIC	2.638	Down-regulation
CMGC_MAPK_JNK_MAPK8_ST	Q9UQF2	MAPK8IP1	P45983	MAPK8	S15	F22L	22	Missense	distal	7	no	8.376	8.379	EPSD	COSMIC	2.638	Up-regulation
CMGC_MAPK_JNK_MAPK8_ST	Q9UQF2	MAPK8IP1	P45983	MAPK8	S15	G10A	10	Missense	distal	-5	no	8.376	7.984	EPSD	COSMIC	2.638	Down-regulation
CMGC_MAPK_JNK_MAPK8_ST	Q9UQF2	MAPK8IP1	P45983	MAPK8	S20	F22L	22	Missense	proximal	2	no	7.803	7.813	EPSD	COSMIC	2.638	Up-regulation
CMGC_MAPK_JNK_MAPK8_ST	Q9UQF2	MAPK8IP1	P45983	MAPK8	S29	F22L	22	Missense	distal	-7	no	8.163	8.164	EPSD	COSMIC	2.638	Up-regulation
CMGC_MAPK_JNK_MAPK8_ST	Q9UQF2	MAPK8IP1	P45983	MAPK8	S29	S29L	29	Missense	central	0	yes	8.163	0.000	EPSD	COSMIC;CCLE	2.638	Loss
CMGC_MAPK_JNK_MAPK8_ST	Q9UQF2	MAPK8IP1	P45983	MAPK8	T103	D102Y	102	Missense	proximal	-1	no	8.001	7.977	EPSD;PhosphoSitePlus	COSMIC	2.638	Down-regulation
CMGC_MAPK_JNK_MAPK8_ST	Q9UQF2	MAPK8IP1	P45983	MAPK8	T103	A99V	99	Missense	distal	-4	no	8.001	7.146	EPSD;PhosphoSitePlus	COSMIC	2.638	Down-regulation
CMGC_MAPK_JNK_MAPK8_ST	Q9UQF2	MAPK8IP1	P45983	MAPK8	S187	R194G	194	Missense	distal	7	no	3.795	3.797	EPSD	COSMIC	2.638	Up-regulation
CMGC_MAPK_JNK_MAPK8_ST	Q9UQF2	MAPK8IP1	P45983	MAPK8	S187	R191Q	191	Missense	distal	4	no	3.795	4.029	EPSD	COSMIC	2.638	Up-regulation
CMGC_MAPK_JNK_MAPK8_ST	Q9UQF2	MAPK8IP1	P45983	MAPK8	S197	K200Q	200	Missense	distal	3	no	7.886	7.983	EPSD	COSMIC	2.638	Up-regulation
CMGC_MAPK_JNK_MAPK8_ST	Q9UQF2	MAPK8IP1	P45983	MAPK8	S197	R194G	194	Missense	distal	-3	no	7.886	7.910	EPSD	COSMIC	2.638	Up-regulation
CMGC_MAPK_JNK_MAPK8_ST	Q9UQF2	MAPK8IP1	P45983	MAPK8	S197	R191Q	191	Missense	distal	-6	no	7.886	7.784	EPSD	COSMIC	2.638	Down-regulation
CMGC_MAPK_JNK_MAPK8_ST	Q9UQF2	MAPK8IP1	P45983	MAPK8	T205	K200Q	200	Missense	distal	-5	no	7.454	7.638	PhosphoSitePlus;EPSD	COSMIC	2.638	Up-regulation
CMGC_MAPK_JNK_MAPK8_ST	Q9UQF2	MAPK8IP1	P45983	MAPK8	S235	R239H	239	Missense	distal	4	no	9.188	9.225	EPSD	COSMIC	2.638	Up-regulation
CMGC_MAPK_JNK_MAPK8_ST	Q9UQF2	MAPK8IP1	P45983	MAPK8	S235	S232Y	232	Missense	distal	-3	no	9.188	8.705	EPSD	COSMIC	2.638	Down-regulation
CMGC_MAPK_JNK_MAPK8_ST	Q9UQF2	MAPK8IP1	P45983	MAPK8	S235	R238C	238	Missense	distal	3	no	9.188	9.171	EPSD	COSMIC	2.638	Down-regulation
CMGC_MAPK_JNK_MAPK8_ST	Q9UQF2	MAPK8IP1	P45983	MAPK8	S235	D234H	234	Missense	proximal	-1	no	9.188	9.182	EPSD	COSMIC	2.638	Down-regulation
CMGC_MAPK_JNK_MAPK8_ST	Q9UQF2	MAPK8IP1	P45983	MAPK8	S235	D228Y	228	Missense	distal	-7	no	9.188	9.201	EPSD	COSMIC	2.638	Up-regulation
CMGC_MAPK_JNK_MAPK8_ST	Q9UQF2	MAPK8IP1	P45983	MAPK8	S235	D228H	228	Missense	distal	-7	no	9.188	9.191	EPSD	COSMIC	2.638	Up-regulation
CMGC_MAPK_JNK_MAPK8_ST	Q9UQF2	MAPK8IP1	P45983	MAPK8	S235	R229H	229	Missense	distal	-6	no	9.188	9.167	EPSD	COSMIC	2.638	Down-regulation
CMGC_MAPK_JNK_MAPK8_ST	Q9UQF2	MAPK8IP1	P45983	MAPK8	T284	P285T	285	Missense	proximal	1	no	7.758	0.771	EPSD	COSMIC	2.638	Loss
CMGC_MAPK_JNK_MAPK8_ST	Q9UQF2	MAPK8IP1	P45983	MAPK8	T284	E280D	280	Missense	distal	-4	no	7.758	7.335	EPSD	COSMIC	2.638	Down-regulation
CMGC_MAPK_JNK_MAPK8_ST	Q9UQF2	MAPK8IP1	P45983	MAPK8	T284	Q287H	287	Missense	distal	3	no	7.758	7.865	EPSD	COSMIC	2.638	Up-regulation
CMGC_MAPK_JNK_MAPK8_ST	Q9UQF2	MAPK8IP1	P45983	MAPK8	S369	Y376C	376	Missense	distal	7	no	3.225	3.184	EPSD	COSMIC	2.638	Down-regulation
CMGC_MAPK_JNK_MAPK8_ST	Q9UQF2	MAPK8IP1	P45983	MAPK8	S421	G428R	428	Missense	distal	7	no	7.986	7.985	EPSD	COSMIC;GDSC;CCLE	2.638	Down-regulation
CMGC_MAPK_JNK_MAPK8_ST	Q9UQF2	MAPK8IP1	P45983	MAPK8	S421	P422T	422	Missense	proximal	1	no	7.986	1.000	EPSD	COSMIC	2.638	Loss
CMGC_MAPK_JNK_MAPK8_ST	Q9UQF2	MAPK8IP1	P45983	MAPK8	S421	S420F	420	Missense	proximal	-1	no	7.986	7.957	EPSD	COSMIC	2.638	Down-regulation
CMGC_MAPK_JNK_MAPK8_ST	Q9UQF2	MAPK8IP1	P45983	MAPK8	S421	S421L	421	Missense	central	0	yes	7.986	0.000	EPSD	COSMIC;GDSC	2.638	Loss
CMGC_MAPK_JNK_MAPK8_ST	Q9UQF2	MAPK8IP1	P45983	MAPK8	T448	E445K	445	Missense	distal	-3	no	9.114	9.140	EPSD	COSMIC	2.638	Up-regulation
CMGC_MAPK_JNK_MAPK8_ST	Q9UQF2	MAPK8IP1	P45983	MAPK8	T448	V454D	454	Missense	distal	6	no	9.114	9.158	EPSD	COSMIC	2.638	Up-regulation
CMGC_MAPK_JNK_MAPK8_ST	Q9UQF2	MAPK8IP1	P45983	MAPK8	T448	P449H	449	Missense	proximal	1	no	9.114	1.198	EPSD	COSMIC	2.638	Loss
CMGC_MAPK_JNK_MAPK8_ST	Q9UQF2	MAPK8IP1	P45983	MAPK8	T448	V454I	454	Missense	distal	6	no	9.114	9.159	EPSD	COSMIC;GDSC	2.638	Up-regulation
CMGC_MAPK_JNK_MAPK8_ST	Q9UQF2	MAPK8IP1	P45983	MAPK8	T448	T448M	448	Missense	central	0	yes	9.114	0.000	EPSD	COSMIC	2.638	Loss
CMGC_MAPK_JNK_MAPK8_ST	Q9UQF2	MAPK8IP1	P45983	MAPK8	T448	D446Y	446	Missense	proximal	-2	no	9.114	9.005	EPSD	COSMIC;GDSC;CCLE	2.638	Down-regulation
CMGC_MAPK_JNK_MAPK8_ST	Q9UQF2	MAPK8IP1	P45983	MAPK8	T448	D450G	450	Missense	proximal	2	no	9.114	9.048	EPSD	COSMIC	2.638	Down-regulation
CMGC_MAPK_JNK_MAPK8_ST	Q07817	BCL2L1	P45983	MAPK8	S62	A64T	64	Missense	proximal	2	no	6.612	6.591	EPSD;PhosphoSitePlus	COSMIC;GDSC;CCLE	2.638	Down-regulation
CMGC_MAPK_JNK_MAPK8_ST	Q07817	BCL2L1	P45983	MAPK8	S62	A60V	60	Missense	proximal	-2	no	6.612	6.421	EPSD;PhosphoSitePlus	COSMIC;GDSC;CCLE	2.638	Down-regulation
CMGC_MAPK_JNK_MAPK8_ST	Q07817	BCL2L1	P45983	MAPK8	T115	L112V	112	Missense	distal	-3	no	7.756	7.703	EPSD;PhosphoSitePlus	COSMIC	2.638	Down-regulation
CMGC_MAPK_JNK_MAPK8_ST	Q07817	BCL2L1	P45983	MAPK8	T115	G117E	117	Missense	proximal	2	no	7.756	8.021	EPSD;PhosphoSitePlus	COSMIC	2.638	Up-regulation
CMGC_MAPK_JNK_MAPK8_ST	Q07817	BCL2L1	P45983	MAPK8	T115	H113Y	113	Missense	proximal	-2	no	7.756	7.706	EPSD;PhosphoSitePlus	COSMIC	2.638	Down-regulation
CMGC_MAPK_JNK_MAPK8_ST	Q07817	BCL2L1	P45983	MAPK8	T115	A119V	119	Missense	distal	4	no	7.756	7.237	EPSD;PhosphoSitePlus	COSMIC	2.638	Down-regulation
CMGC_MAPK_JNK_MAPK8_ST	O43561	LAT	P45983	MAPK8	S84	S84F	84	Missense	central	0	yes	6.397	0.000	EPSD	COSMIC	2.638	Loss
CMGC_MAPK_JNK_MAPK8_ST	O43561	LAT	P45983	MAPK8	S84	P85S	85	Missense	proximal	1	no	6.397	-1.332	EPSD	COSMIC	2.638	Loss
CMGC_MAPK_JNK_MAPK8_ST	O43561	LAT	P45983	MAPK8	T94	S96I	96	Missense	proximal	2	no	6.976	6.854	EPSD	COSMIC	2.638	Down-regulation
CMGC_MAPK_JNK_MAPK8_ST	O43561	LAT	P45983	MAPK8	T94	T94M	94	Missense	central	0	yes	6.976	0.000	EPSD	COSMIC	2.638	Loss
CMGC_MAPK_JNK_MAPK8_ST	O43561	LAT	P45983	MAPK8	T94	R93Q	93	Missense	proximal	-1	no	6.976	6.997	EPSD	COSMIC	2.638	Up-regulation
CMGC_MAPK_JNK_MAPK8_ST	O43561	LAT	P45983	MAPK8	T94	S97F	97	Missense	distal	3	no	6.976	7.196	EPSD	COSMIC	2.638	Up-regulation
CMGC_MAPK_JNK_MAPK8_ST	O43561	LAT	P45983	MAPK8	T94	P95S	95	Missense	proximal	1	no	6.976	-0.752	EPSD	COSMIC	2.638	Loss
CMGC_MAPK_JNK_MAPK8_ST	O43561	LAT	P45983	MAPK8	T94	R98W	98	Missense	distal	4	no	6.976	6.949	EPSD	COSMIC	2.638	Down-regulation
CMGC_MAPK_JNK_MAPK8_ST	O43561	LAT	P45983	MAPK8	T184	R188W	188	Missense	distal	4	no	6.350	6.322	EPSD	COSMIC	2.638	Down-regulation
CMGC_MAPK_JNK_MAPK8_ST	O43561	LAT	P45983	MAPK8	T184	A181S	181	Missense	distal	-3	no	6.350	6.314	EPSD	COSMIC	2.638	Down-regulation
CMGC_MAPK_JNK_MAPK8_ST	O43561	LAT	P45983	MAPK8	T184	R188L	188	Missense	distal	4	no	6.350	6.283	EPSD	COSMIC	2.638	Down-regulation
CMGC_MAPK_JNK_MAPK8_ST	O43561	LAT	P45983	MAPK8	S209	A210S	210	Missense	proximal	1	no	2.910	1.529	EPSD	COSMIC	2.638	Loss
CMGC_MAPK_JNK_MAPK8_ST	O43561	LAT	P45983	MAPK8	S217	R218W	218	Missense	proximal	1	no	1.192	2.655	EPSD	COSMIC	2.638	Gain
CMGC_MAPK_JNK_MAPK8_ST	P42226	STAT6	P45983	MAPK8	S498	Q501L	501	Missense	distal	3	no	3.007	3.177	EPSD	COSMIC	2.638	Up-regulation
CMGC_MAPK_JNK_MAPK8_ST	P42226	STAT6	P45983	MAPK8	S498	Q501E	501	Missense	distal	3	no	3.007	2.963	EPSD	COSMIC	2.638	Down-regulation
CMGC_MAPK_JNK_MAPK8_ST	P42226	STAT6	P45983	MAPK8	S707	L706I	706	Missense	proximal	-1	no	6.698	6.714	PhosphoSitePlus	COSMIC	2.638	Up-regulation
CMGC_MAPK_JNK_MAPK8_ST	P42226	STAT6	P45983	MAPK8	S756	L761F	761	Missense	distal	5	no	7.835	7.829	EPSD	COSMIC;GDSC;CCLE	2.638	Down-regulation
CMGC_MAPK_JNK_MAPK8_ST	P42226	STAT6	P45983	MAPK8	S756	A753V	753	Missense	distal	-3	no	7.835	7.406	EPSD	COSMIC	2.638	Down-regulation
CMGC_MAPK_JNK_MAPK8_ST	Q13363	CTBP1	P45983	MAPK8	S422	H416P	416	Missense	distal	-6	no	8.934	8.890	PhosphoSitePlus	COSMIC	2.638	Down-regulation
CMGC_MAPK_JNK_MAPK8_ST	Q13363	CTBP1	P45983	MAPK8	S422	V427I	427	Missense	distal	5	no	8.934	8.901	PhosphoSitePlus	COSMIC;CCLE	2.638	Down-regulation
CMGC_MAPK_JNK_MAPK8_ST	Q13363	CTBP1	P45983	MAPK8	S422	V427A	427	Missense	distal	5	no	8.934	8.861	PhosphoSitePlus	COSMIC	2.638	Down-regulation
CMGC_MAPK_JNK_MAPK8_ST	Q13363	CTBP1	P45983	MAPK8	S422	T426N	426	Missense	distal	4	no	8.934	8.535	PhosphoSitePlus	COSMIC	2.638	Down-regulation
CMGC_MAPK_JNK_MAPK8_ST	Q13363	CTBP1	P45983	MAPK8	S422	H419P	419	Missense	distal	-3	no	8.934	9.039	PhosphoSitePlus	COSMIC	2.638	Up-regulation
CMGC_MAPK_JNK_MAPK8_ST	Q13363	CTBP1	P45983	MAPK8	S422	H416Q	416	Missense	distal	-6	no	8.934	8.854	PhosphoSitePlus	COSMIC	2.638	Down-regulation
CMGC_MAPK_JNK_MAPK8_ST	Q13950	RUNX2	P45983	MAPK8	S28	P29H	29	Missense	proximal	1	no	6.942	-0.974	EPSD	COSMIC	2.638	Loss
CMGC_MAPK_JNK_MAPK8_ST	Q13950	RUNX2	P45983	MAPK8	S43	P36S	36	Missense	distal	-7	no	6.287	6.281	EPSD	COSMIC	2.638	Down-regulation
CMGC_MAPK_JNK_MAPK8_ST	Q13950	RUNX2	P45983	MAPK8	S118	D117N	117	Missense	proximal	-1	no	6.671	6.656	PhosphoSitePlus	COSMIC	2.638	Down-regulation
CMGC_MAPK_JNK_MAPK8_ST	Q13950	RUNX2	P45983	MAPK8	S118	L122M	122	Missense	distal	4	no	6.671	6.693	PhosphoSitePlus	COSMIC	2.638	Up-regulation
CMGC_MAPK_JNK_MAPK8_ST	Q13950	RUNX2	P45983	MAPK8	T200	V203F	203	Missense	distal	3	no	2.782	2.755	EPSD	COSMIC	2.638	Down-regulation
CMGC_MAPK_JNK_MAPK8_ST	Q13950	RUNX2	P45983	MAPK8	S275	P274S	274	Missense	proximal	-1	no	8.216	8.226	EPSD	COSMIC	2.638	Up-regulation
CMGC_MAPK_JNK_MAPK8_ST	Q13950	RUNX2	P45983	MAPK8	S275	A273G	273	Missense	proximal	-2	no	8.216	8.095	EPSD	COSMIC	2.638	Down-regulation
CMGC_MAPK_JNK_MAPK8_ST	Q13950	RUNX2	P45983	MAPK8	T286	S293P	293	Missense	distal	7	no	2.842	2.880	EPSD	COSMIC	2.638	Up-regulation
CMGC_MAPK_JNK_MAPK8_ST	Q13950	RUNX2	P45983	MAPK8	S294	S293P	293	Missense	proximal	-1	no	8.601	8.591	EPSD	COSMIC	2.638	Down-regulation
CMGC_MAPK_JNK_MAPK8_ST	Q13950	RUNX2	P45983	MAPK8	S294	S298F	298	Missense	distal	4	no	8.601	8.143	EPSD	COSMIC	2.638	Down-regulation
CMGC_MAPK_JNK_MAPK8_ST	Q13950	RUNX2	P45983	MAPK8	S305	S305F	305	Missense	central	0	yes	2.720	0.000	EPSD	COSMIC	2.638	Loss
CMGC_MAPK_JNK_MAPK8_ST	Q13950	RUNX2	P45983	MAPK8	S305	S308F	308	Missense	distal	3	no	2.720	2.939	EPSD	COSMIC	2.638	Up-regulation
CMGC_MAPK_JNK_MAPK8_ST	Q13950	RUNX2	P45983	MAPK8	S305	S298F	298	Missense	distal	-7	no	2.720	2.736	EPSD	COSMIC	2.638	Up-regulation
CMGC_MAPK_JNK_MAPK8_ST	Q13950	RUNX2	P45983	MAPK8	S312	S305F	305	Missense	distal	-7	no	9.441	9.457	EPSD	COSMIC	2.638	Up-regulation
CMGC_MAPK_JNK_MAPK8_ST	Q13950	RUNX2	P45983	MAPK8	S312	S305T	305	Missense	distal	-7	no	9.441	9.443	EPSD	COSMIC	2.638	Up-regulation
CMGC_MAPK_JNK_MAPK8_ST	Q13950	RUNX2	P45983	MAPK8	S312	S308F	308	Missense	distal	-4	no	9.441	8.503	EPSD	COSMIC	2.638	Down-regulation
CMGC_MAPK_JNK_MAPK8_ST	Q13950	RUNX2	P45983	MAPK8	T319	R325P	325	Missense	distal	6	no	8.050	8.086	EPSD	COSMIC	2.638	Up-regulation
CMGC_MAPK_JNK_MAPK8_ST	Q13950	RUNX2	P45983	MAPK8	T319	S322F	322	Missense	distal	3	no	8.050	8.269	EPSD	COSMIC	2.638	Up-regulation
CMGC_MAPK_JNK_MAPK8_ST	Q13950	RUNX2	P45983	MAPK8	T319	P320T	320	Missense	proximal	1	no	8.050	1.063	EPSD	COSMIC	2.638	Loss
CMGC_MAPK_JNK_MAPK8_ST	Q13950	RUNX2	P45983	MAPK8	T324	R325P	325	Missense	proximal	1	no	-1.115	6.021	EPSD	COSMIC	2.638	Gain
CMGC_MAPK_JNK_MAPK8_ST	Q13950	RUNX2	P45983	MAPK8	S465	S467F	467	Missense	proximal	2	no	5.598	5.326	EPSD	COSMIC	2.638	Down-regulation
CMGC_MAPK_JNK_MAPK8_ST	Q13950	RUNX2	P45983	MAPK8	S465	S467Y	467	Missense	proximal	2	no	5.598	5.221	EPSD	COSMIC	2.638	Down-regulation
CMGC_MAPK_JNK_MAPK8_ST	Q13950	RUNX2	P45983	MAPK8	S465	P472T	472	Missense	distal	7	no	5.598	5.567	EPSD	COSMIC	2.638	Down-regulation
CMGC_MAPK_JNK_MAPK8_ST	Q13950	RUNX2	P45983	MAPK8	S465	G462E	462	Missense	distal	-3	no	5.598	5.931	EPSD	COSMIC	2.638	Up-regulation
CMGC_MAPK_JNK_MAPK8_ST	Q13950	RUNX2	P45983	MAPK8	S465	P466H	466	Missense	proximal	1	no	5.598	-2.318	EPSD	COSMIC	2.638	Loss
CMGC_MAPK_JNK_MAPK8_ST	Q13950	RUNX2	P45983	MAPK8	S465	P466L	466	Missense	proximal	1	no	5.598	-1.975	EPSD	COSMIC	2.638	Loss
CMGC_MAPK_JNK_MAPK8_ST	Q13950	RUNX2	P45983	MAPK8	S503	S503F	503	Missense	central	0	yes	7.796	0.000	EPSD	COSMIC	2.638	Loss
CMGC_MAPK_JNK_MAPK8_ST	Q13950	RUNX2	P45983	MAPK8	S503	A496T	496	Missense	distal	-7	no	7.796	7.798	EPSD	COSMIC	2.638	Up-regulation
CMGC_MAPK_JNK_MAPK8_ST	Q14934	NFATC4	P45983	MAPK8	S73	P75H	75	Missense	proximal	2	no	7.174	7.176	EPSD	COSMIC	2.638	Up-regulation
CMGC_MAPK_JNK_MAPK8_ST	Q14934	NFATC4	P45983	MAPK8	S73	P66H	66	Missense	distal	-7	no	7.174	7.180	EPSD	COSMIC	2.638	Up-regulation
CMGC_MAPK_JNK_MAPK8_ST	Q14934	NFATC4	P45983	MAPK8	S73	P66A	66	Missense	distal	-7	no	7.174	7.169	EPSD	COSMIC	2.638	Down-regulation
CMGC_MAPK_JNK_MAPK8_ST	Q14934	NFATC4	P45983	MAPK8	S73	P69L	69	Missense	distal	-4	no	7.174	6.847	EPSD	COSMIC	2.638	Down-regulation
CMGC_MAPK_JNK_MAPK8_ST	Q14934	NFATC4	P45983	MAPK8	S73	R77Q	77	Missense	distal	4	no	7.174	7.408	EPSD	COSMIC	2.638	Up-regulation
CMGC_MAPK_JNK_MAPK8_ST	Q14934	NFATC4	P45983	MAPK8	S73	P78A	78	Missense	distal	5	no	7.174	7.100	EPSD	COSMIC	2.638	Down-regulation
CMGC_MAPK_JNK_MAPK8_ST	Q14934	NFATC4	P45983	MAPK8	S73	S73L	73	Missense	central	0	yes	7.174	0.000	EPSD	COSMIC	2.638	Loss
CMGC_MAPK_JNK_MAPK8_ST	Q14934	NFATC4	P45983	MAPK8	S122	P125H	125	Missense	distal	3	no	8.630	8.668	EPSD	COSMIC	2.638	Up-regulation
CMGC_MAPK_JNK_MAPK8_ST	Q14934	NFATC4	P45983	MAPK8	S122	P128S	128	Missense	distal	6	no	8.630	8.655	EPSD	COSMIC	2.638	Up-regulation
CMGC_MAPK_JNK_MAPK8_ST	Q14934	NFATC4	P45983	MAPK8	S122	S122C	122	Missense	central	0	yes	8.630	0.000	EPSD	COSMIC	2.638	Loss
CMGC_MAPK_JNK_MAPK8_ST	Q14934	NFATC4	P45983	MAPK8	S122	S120Y	120	Missense	proximal	-2	no	8.630	8.502	EPSD	COSMIC	2.638	Down-regulation
CMGC_MAPK_JNK_MAPK8_ST	Q14934	NFATC4	P45983	MAPK8	S122	P123S	123	Missense	proximal	1	no	8.630	0.902	EPSD	COSMIC	2.638	Loss
CMGC_MAPK_JNK_MAPK8_ST	Q14934	NFATC4	P45983	MAPK8	S122	P125Q	125	Missense	distal	3	no	8.630	8.561	EPSD	COSMIC	2.638	Down-regulation
CMGC_MAPK_JNK_MAPK8_ST	Q14934	NFATC4	P45983	MAPK8	S122	P127L	127	Missense	distal	5	no	8.630	8.629	EPSD	COSMIC	2.638	Down-regulation
CMGC_MAPK_JNK_MAPK8_ST	Q14934	NFATC4	P45983	MAPK8	S122	T124M	124	Missense	proximal	2	no	8.630	8.379	EPSD	COSMIC	2.638	Down-regulation
CMGC_MAPK_JNK_MAPK8_ST	Q14934	NFATC4	P45983	MAPK8	T124	P125H	125	Missense	proximal	1	no	9.770	1.854	EPSD	COSMIC	2.638	Loss
CMGC_MAPK_JNK_MAPK8_ST	Q14934	NFATC4	P45983	MAPK8	T124	P128S	128	Missense	distal	4	no	9.770	9.795	EPSD	COSMIC	2.638	Up-regulation
CMGC_MAPK_JNK_MAPK8_ST	Q14934	NFATC4	P45983	MAPK8	T124	S122C	122	Missense	proximal	-2	no	9.770	9.706	EPSD	COSMIC	2.638	Down-regulation
CMGC_MAPK_JNK_MAPK8_ST	Q14934	NFATC4	P45983	MAPK8	T124	S120Y	120	Missense	distal	-4	no	9.770	8.536	EPSD	COSMIC	2.638	Down-regulation
CMGC_MAPK_JNK_MAPK8_ST	Q14934	NFATC4	P45983	MAPK8	T124	P123S	123	Missense	proximal	-1	no	9.770	9.780	EPSD	COSMIC	2.638	Up-regulation
CMGC_MAPK_JNK_MAPK8_ST	Q14934	NFATC4	P45983	MAPK8	T124	P125Q	125	Missense	proximal	1	no	9.770	2.660	EPSD	COSMIC	2.638	Down-regulation
CMGC_MAPK_JNK_MAPK8_ST	Q14934	NFATC4	P45983	MAPK8	T124	P127L	127	Missense	distal	3	no	9.770	9.871	EPSD	COSMIC	2.638	Up-regulation
CMGC_MAPK_JNK_MAPK8_ST	Q14934	NFATC4	P45983	MAPK8	T124	A130V	130	Missense	distal	6	no	9.770	9.694	EPSD	COSMIC	2.638	Down-regulation
CMGC_MAPK_JNK_MAPK8_ST	Q14934	NFATC4	P45983	MAPK8	T124	T124M	124	Missense	central	0	yes	9.770	0.000	EPSD	COSMIC	2.638	Loss
CMGC_MAPK_JNK_MAPK8_ST	Q14934	NFATC4	P45983	MAPK8	S142	P148S	148	Missense	distal	6	no	7.205	7.230	EPSD	COSMIC	2.638	Up-regulation
CMGC_MAPK_JNK_MAPK8_ST	Q14934	NFATC4	P45983	MAPK8	S142	G141W	141	Missense	proximal	-1	no	7.205	7.201	EPSD	COSMIC	2.638	Down-regulation
CMGC_MAPK_JNK_MAPK8_ST	Q14934	NFATC4	P45983	MAPK8	S142	R144I	144	Missense	proximal	2	no	7.205	7.324	EPSD	COSMIC	2.638	Up-regulation
CMGC_MAPK_JNK_MAPK8_ST	Q14934	NFATC4	P45983	MAPK8	S142	P149Q	149	Missense	distal	7	no	7.205	7.184	EPSD	COSMIC	2.638	Down-regulation
CMGC_MAPK_JNK_MAPK8_ST	Q14934	NFATC4	P45983	MAPK8	S142	R144K	144	Missense	proximal	2	no	7.205	7.528	EPSD	COSMIC	2.638	Up-regulation
CMGC_MAPK_JNK_MAPK8_ST	Q14934	NFATC4	P45983	MAPK8	S142	W138L	138	Missense	distal	-4	no	7.205	7.259	EPSD	COSMIC	2.638	Up-regulation
CMGC_MAPK_JNK_MAPK8_ST	Q14934	NFATC4	P45983	MAPK8	S168	G163W	163	Missense	distal	-5	no	7.207	7.281	EPSD	COSMIC;GDSC;CCLE	2.638	Up-regulation
CMGC_MAPK_JNK_MAPK8_ST	Q14934	NFATC4	P45983	MAPK8	S168	S168N	168	Missense	central	0	yes	7.207	0.000	EPSD	COSMIC	2.638	Loss
CMGC_MAPK_JNK_MAPK8_ST	Q14934	NFATC4	P45983	MAPK8	S168	G163R	163	Missense	distal	-5	no	7.207	7.235	EPSD	COSMIC	2.638	Up-regulation
CMGC_MAPK_JNK_MAPK8_ST	Q14934	NFATC4	P45983	MAPK8	S168	G162V	162	Missense	distal	-6	no	7.207	7.261	EPSD	COSMIC	2.638	Up-regulation
CMGC_MAPK_JNK_MAPK8_ST	Q14934	NFATC4	P45983	MAPK8	S170	G163W	163	Missense	distal	-7	no	6.016	6.019	EPSD	COSMIC;GDSC;CCLE	2.638	Up-regulation
CMGC_MAPK_JNK_MAPK8_ST	Q14934	NFATC4	P45983	MAPK8	S170	S168N	168	Missense	proximal	-2	no	6.016	5.898	EPSD	COSMIC	2.638	Down-regulation
CMGC_MAPK_JNK_MAPK8_ST	Q14934	NFATC4	P45983	MAPK8	S213	R219I	219	Missense	distal	6	no	8.037	8.064	EPSD;PhosphoSitePlus	COSMIC	2.638	Up-regulation
CMGC_MAPK_JNK_MAPK8_ST	Q14934	NFATC4	P45983	MAPK8	S213	R208C	208	Missense	distal	-5	no	8.037	7.938	EPSD;PhosphoSitePlus	COSMIC	2.638	Down-regulation
CMGC_MAPK_JNK_MAPK8_ST	Q14934	NFATC4	P45983	MAPK8	S213	S217L	217	Missense	distal	4	no	8.037	7.606	EPSD;PhosphoSitePlus	COSMIC;CCLE	2.638	Down-regulation
CMGC_MAPK_JNK_MAPK8_ST	Q14934	NFATC4	P45983	MAPK8	S213	R219Q	219	Missense	distal	6	no	8.037	8.083	EPSD;PhosphoSitePlus	COSMIC	2.638	Up-regulation
CMGC_MAPK_JNK_MAPK8_ST	Q14934	NFATC4	P45983	MAPK8	S213	S207F	207	Missense	distal	-6	no	8.037	8.218	EPSD;PhosphoSitePlus	COSMIC	2.638	Up-regulation
CMGC_MAPK_JNK_MAPK8_ST	Q14934	NFATC4	P45983	MAPK8	S213	P216L	216	Missense	distal	3	no	8.037	8.139	EPSD;PhosphoSitePlus	COSMIC	2.638	Up-regulation
CMGC_MAPK_JNK_MAPK8_ST	Q14934	NFATC4	P45983	MAPK8	S213	P214Q	214	Missense	proximal	1	no	8.037	0.928	EPSD;PhosphoSitePlus	COSMIC	2.638	Loss
CMGC_MAPK_JNK_MAPK8_ST	Q14934	NFATC4	P45983	MAPK8	S213	A206T	206	Missense	distal	-7	no	8.037	8.039	EPSD;PhosphoSitePlus	COSMIC	2.638	Up-regulation
CMGC_MAPK_JNK_MAPK8_ST	Q14934	NFATC4	P45983	MAPK8	S217	R219I	219	Missense	proximal	2	no	7.333	7.452	PhosphoSitePlus;EPSD	COSMIC	2.638	Up-regulation
CMGC_MAPK_JNK_MAPK8_ST	Q14934	NFATC4	P45983	MAPK8	S217	S217L	217	Missense	central	0	yes	7.333	0.000	PhosphoSitePlus;EPSD	COSMIC;CCLE	2.638	Loss
CMGC_MAPK_JNK_MAPK8_ST	Q14934	NFATC4	P45983	MAPK8	S217	R219Q	219	Missense	proximal	2	no	7.333	7.508	PhosphoSitePlus;EPSD	COSMIC	2.638	Up-regulation
CMGC_MAPK_JNK_MAPK8_ST	Q14934	NFATC4	P45983	MAPK8	S217	P216L	216	Missense	proximal	-1	no	7.333	7.315	PhosphoSitePlus;EPSD	COSMIC	2.638	Down-regulation
CMGC_MAPK_JNK_MAPK8_ST	Q14934	NFATC4	P45983	MAPK8	S217	P214Q	214	Missense	distal	-3	no	7.333	7.390	PhosphoSitePlus;EPSD	COSMIC	2.638	Up-regulation
CMGC_MAPK_JNK_MAPK8_ST	Q14934	NFATC4	P45983	MAPK8	S217	P224T	224	Missense	distal	7	no	7.333	7.302	PhosphoSitePlus;EPSD	COSMIC	2.638	Down-regulation
CMGC_MAPK_JNK_MAPK8_ST	Q14934	NFATC4	P45983	MAPK8	S217	R223W	223	Missense	distal	6	no	7.333	7.324	PhosphoSitePlus;EPSD	COSMIC	2.638	Down-regulation
CMGC_MAPK_JNK_MAPK8_ST	Q14934	NFATC4	P45983	MAPK8	S221	R219I	219	Missense	proximal	-2	no	7.409	7.489	EPSD	COSMIC	2.638	Up-regulation
CMGC_MAPK_JNK_MAPK8_ST	Q14934	NFATC4	P45983	MAPK8	S221	P227Q	227	Missense	distal	6	no	7.409	7.419	EPSD	COSMIC	2.638	Up-regulation
CMGC_MAPK_JNK_MAPK8_ST	Q14934	NFATC4	P45983	MAPK8	S221	P227H	227	Missense	distal	6	no	7.409	7.386	EPSD	COSMIC	2.638	Down-regulation
CMGC_MAPK_JNK_MAPK8_ST	Q14934	NFATC4	P45983	MAPK8	S221	E228K	228	Missense	distal	7	no	7.409	7.394	EPSD	COSMIC	2.638	Down-regulation
CMGC_MAPK_JNK_MAPK8_ST	Q14934	NFATC4	P45983	MAPK8	S221	S217L	217	Missense	distal	-4	no	7.409	6.418	EPSD	COSMIC;CCLE	2.638	Down-regulation
CMGC_MAPK_JNK_MAPK8_ST	Q14934	NFATC4	P45983	MAPK8	S221	R219Q	219	Missense	proximal	-2	no	7.409	7.483	EPSD	COSMIC	2.638	Up-regulation
CMGC_MAPK_JNK_MAPK8_ST	Q14934	NFATC4	P45983	MAPK8	S221	P216L	216	Missense	distal	-5	no	7.409	7.769	EPSD	COSMIC	2.638	Up-regulation
CMGC_MAPK_JNK_MAPK8_ST	Q14934	NFATC4	P45983	MAPK8	S221	P214Q	214	Missense	distal	-7	no	7.409	7.407	EPSD	COSMIC	2.638	Down-regulation
CMGC_MAPK_JNK_MAPK8_ST	Q14934	NFATC4	P45983	MAPK8	S221	P224T	224	Missense	distal	3	no	7.409	7.311	EPSD	COSMIC	2.638	Down-regulation
CMGC_MAPK_JNK_MAPK8_ST	Q14934	NFATC4	P45983	MAPK8	S221	R223W	223	Missense	proximal	2	no	7.409	7.337	EPSD	COSMIC	2.638	Down-regulation
CMGC_MAPK_JNK_MAPK8_ST	Q14934	NFATC4	P45983	MAPK8	S221	T226S	226	Missense	distal	5	no	7.409	7.403	EPSD	COSMIC	2.638	Down-regulation
CMGC_MAPK_JNK_MAPK8_ST	Q14934	NFATC4	P45983	MAPK8	T226	R219I	219	Missense	distal	-7	no	7.296	7.291	EPSD	COSMIC	2.638	Down-regulation
CMGC_MAPK_JNK_MAPK8_ST	Q14934	NFATC4	P45983	MAPK8	T226	P227Q	227	Missense	proximal	1	no	7.296	0.187	EPSD	COSMIC	2.638	Loss
CMGC_MAPK_JNK_MAPK8_ST	Q14934	NFATC4	P45983	MAPK8	T226	P227H	227	Missense	proximal	1	no	7.296	-0.619	EPSD	COSMIC	2.638	Loss
CMGC_MAPK_JNK_MAPK8_ST	Q14934	NFATC4	P45983	MAPK8	T226	E228K	228	Missense	proximal	2	no	7.296	7.314	EPSD	COSMIC	2.638	Up-regulation
CMGC_MAPK_JNK_MAPK8_ST	Q14934	NFATC4	P45983	MAPK8	T226	R219Q	219	Missense	distal	-7	no	7.296	7.286	EPSD	COSMIC	2.638	Down-regulation
CMGC_MAPK_JNK_MAPK8_ST	Q14934	NFATC4	P45983	MAPK8	T226	P224T	224	Missense	proximal	-2	no	7.296	7.216	EPSD	COSMIC	2.638	Down-regulation
CMGC_MAPK_JNK_MAPK8_ST	Q14934	NFATC4	P45983	MAPK8	T226	R223W	223	Missense	distal	-3	no	7.296	7.211	EPSD	COSMIC	2.638	Down-regulation
CMGC_MAPK_JNK_MAPK8_ST	Q14934	NFATC4	P45983	MAPK8	T226	W231S	231	Missense	distal	5	no	7.296	7.202	EPSD	COSMIC	2.638	Down-regulation
CMGC_MAPK_JNK_MAPK8_ST	Q14934	NFATC4	P45983	MAPK8	S237	G235S	235	Missense	proximal	-2	no	7.383	7.449	EPSD	COSMIC	2.638	Up-regulation
CMGC_MAPK_JNK_MAPK8_ST	Q14934	NFATC4	P45983	MAPK8	S237	R241L	241	Missense	distal	4	no	7.383	7.316	EPSD	COSMIC	2.638	Down-regulation
CMGC_MAPK_JNK_MAPK8_ST	Q14934	NFATC4	P45983	MAPK8	S237	R241Q	241	Missense	distal	4	no	7.383	7.617	EPSD	COSMIC	2.638	Up-regulation
CMGC_MAPK_JNK_MAPK8_ST	Q14934	NFATC4	P45983	MAPK8	S237	W231S	231	Missense	distal	-6	no	7.383	7.202	EPSD	COSMIC	2.638	Down-regulation
CMGC_MAPK_JNK_MAPK8_ST	Q14934	NFATC4	P45983	MAPK8	S246	P253L	253	Missense	distal	7	no	3.524	3.564	EPSD	COSMIC	2.638	Up-regulation
CMGC_MAPK_JNK_MAPK8_ST	Q14934	NFATC4	P45983	MAPK8	S246	R241L	241	Missense	distal	-5	no	3.524	3.592	EPSD	COSMIC	2.638	Up-regulation
CMGC_MAPK_JNK_MAPK8_ST	Q14934	NFATC4	P45983	MAPK8	S246	R241Q	241	Missense	distal	-5	no	3.524	3.209	EPSD	COSMIC	2.638	Down-regulation
CMGC_MAPK_JNK_MAPK8_ST	Q14934	NFATC4	P45983	MAPK8	T256	P257S	257	Missense	proximal	1	no	8.448	0.719	EPSD	COSMIC	2.638	Loss
CMGC_MAPK_JNK_MAPK8_ST	Q14934	NFATC4	P45983	MAPK8	T256	R261W	261	Missense	distal	5	no	8.448	8.470	EPSD	COSMIC	2.638	Up-regulation
CMGC_MAPK_JNK_MAPK8_ST	Q14934	NFATC4	P45983	MAPK8	T256	P253L	253	Missense	distal	-3	no	8.448	8.269	EPSD	COSMIC	2.638	Down-regulation
CMGC_MAPK_JNK_MAPK8_ST	Q14934	NFATC4	P45983	MAPK8	T256	P260Q	260	Missense	distal	4	no	8.448	8.342	EPSD	COSMIC	2.638	Down-regulation
CMGC_MAPK_JNK_MAPK8_ST	Q14934	NFATC4	P45983	MAPK8	T256	R261Q	261	Missense	distal	5	no	8.448	8.397	EPSD	COSMIC	2.638	Down-regulation
CMGC_MAPK_JNK_MAPK8_ST	Q14934	NFATC4	P45983	MAPK8	T256	S259F	259	Missense	distal	3	no	8.448	8.668	EPSD	COSMIC	2.638	Up-regulation
CMGC_MAPK_JNK_MAPK8_ST	Q14934	NFATC4	P45983	MAPK8	S259	P257S	257	Missense	proximal	-2	no	7.710	7.604	EPSD	COSMIC	2.638	Down-regulation
CMGC_MAPK_JNK_MAPK8_ST	Q14934	NFATC4	P45983	MAPK8	S259	R261W	261	Missense	proximal	2	no	7.710	7.638	EPSD	COSMIC	2.638	Down-regulation
CMGC_MAPK_JNK_MAPK8_ST	Q14934	NFATC4	P45983	MAPK8	S259	P253L	253	Missense	distal	-6	no	7.710	7.801	EPSD	COSMIC	2.638	Up-regulation
CMGC_MAPK_JNK_MAPK8_ST	Q14934	NFATC4	P45983	MAPK8	S259	P260Q	260	Missense	proximal	1	no	7.710	0.601	EPSD	COSMIC	2.638	Loss
CMGC_MAPK_JNK_MAPK8_ST	Q14934	NFATC4	P45983	MAPK8	S259	R261Q	261	Missense	proximal	2	no	7.710	7.885	EPSD	COSMIC	2.638	Up-regulation
CMGC_MAPK_JNK_MAPK8_ST	Q14934	NFATC4	P45983	MAPK8	S259	P265L	265	Missense	distal	6	no	7.710	7.663	EPSD	COSMIC	2.638	Down-regulation
CMGC_MAPK_JNK_MAPK8_ST	Q14934	NFATC4	P45983	MAPK8	S259	S259F	259	Missense	central	0	yes	7.710	0.000	EPSD	COSMIC	2.638	Loss
CMGC_MAPK_JNK_MAPK8_ST	Q14934	NFATC4	P45983	MAPK8	S264	P257S	257	Missense	distal	-7	no	7.666	7.660	EPSD	COSMIC	2.638	Down-regulation
CMGC_MAPK_JNK_MAPK8_ST	Q14934	NFATC4	P45983	MAPK8	S264	R261W	261	Missense	distal	-3	no	7.666	7.580	EPSD	COSMIC	2.638	Down-regulation
CMGC_MAPK_JNK_MAPK8_ST	Q14934	NFATC4	P45983	MAPK8	S264	P260Q	260	Missense	distal	-4	no	7.666	8.050	EPSD	COSMIC	2.638	Up-regulation
CMGC_MAPK_JNK_MAPK8_ST	Q14934	NFATC4	P45983	MAPK8	S264	R261Q	261	Missense	distal	-3	no	7.666	7.865	EPSD	COSMIC	2.638	Up-regulation
CMGC_MAPK_JNK_MAPK8_ST	Q14934	NFATC4	P45983	MAPK8	S264	P265L	265	Missense	proximal	1	no	7.666	0.093	EPSD	COSMIC	2.638	Loss
CMGC_MAPK_JNK_MAPK8_ST	Q14934	NFATC4	P45983	MAPK8	S264	Y271H	271	Missense	distal	7	no	7.666	7.625	EPSD	COSMIC	2.638	Down-regulation
CMGC_MAPK_JNK_MAPK8_ST	Q14934	NFATC4	P45983	MAPK8	S264	R269Q	269	Missense	distal	5	no	7.666	7.614	EPSD	COSMIC	2.638	Down-regulation
CMGC_MAPK_JNK_MAPK8_ST	Q14934	NFATC4	P45983	MAPK8	S264	R269W	269	Missense	distal	5	no	7.666	7.688	EPSD	COSMIC	2.638	Up-regulation
CMGC_MAPK_JNK_MAPK8_ST	Q14934	NFATC4	P45983	MAPK8	S264	R270H	270	Missense	distal	6	no	7.666	7.678	EPSD	COSMIC	2.638	Up-regulation
CMGC_MAPK_JNK_MAPK8_ST	Q14934	NFATC4	P45983	MAPK8	S264	R270C	270	Missense	distal	6	no	7.666	7.678	EPSD	COSMIC	2.638	Up-regulation
CMGC_MAPK_JNK_MAPK8_ST	Q14934	NFATC4	P45983	MAPK8	S264	S259F	259	Missense	distal	-5	no	7.666	8.135	EPSD	COSMIC	2.638	Up-regulation
CMGC_MAPK_JNK_MAPK8_ST	Q14934	NFATC4	P45983	MAPK8	T276	P277Q	277	Missense	proximal	1	no	9.318	2.209	EPSD	COSMIC	2.638	Loss
CMGC_MAPK_JNK_MAPK8_ST	Q14934	NFATC4	P45983	MAPK8	T276	S272F	272	Missense	distal	-4	no	9.318	8.380	EPSD	COSMIC	2.638	Down-regulation
CMGC_MAPK_JNK_MAPK8_ST	Q14934	NFATC4	P45983	MAPK8	T276	G275S	275	Missense	proximal	-1	no	9.318	9.342	EPSD	COSMIC	2.638	Up-regulation
CMGC_MAPK_JNK_MAPK8_ST	Q14934	NFATC4	P45983	MAPK8	T276	S273L	273	Missense	distal	-3	no	9.318	8.977	EPSD	COSMIC	2.638	Down-regulation
CMGC_MAPK_JNK_MAPK8_ST	Q14934	NFATC4	P45983	MAPK8	T276	P282A	282	Missense	distal	6	no	9.318	9.339	EPSD	COSMIC	2.638	Up-regulation
CMGC_MAPK_JNK_MAPK8_ST	Q14934	NFATC4	P45983	MAPK8	T276	Y271H	271	Missense	distal	-5	no	9.318	9.026	EPSD	COSMIC	2.638	Down-regulation
CMGC_MAPK_JNK_MAPK8_ST	Q14934	NFATC4	P45983	MAPK8	T276	R269Q	269	Missense	distal	-7	no	9.318	9.308	EPSD	COSMIC	2.638	Down-regulation
CMGC_MAPK_JNK_MAPK8_ST	Q14934	NFATC4	P45983	MAPK8	T276	S272P	272	Missense	distal	-4	no	9.318	8.653	EPSD	COSMIC	2.638	Down-regulation
CMGC_MAPK_JNK_MAPK8_ST	Q14934	NFATC4	P45983	MAPK8	T276	R269W	269	Missense	distal	-7	no	9.318	9.321	EPSD	COSMIC	2.638	Up-regulation
CMGC_MAPK_JNK_MAPK8_ST	Q14934	NFATC4	P45983	MAPK8	T276	S281F	281	Missense	distal	5	no	9.318	9.394	EPSD	COSMIC	2.638	Up-regulation
CMGC_MAPK_JNK_MAPK8_ST	Q14934	NFATC4	P45983	MAPK8	T276	R270H	270	Missense	distal	-6	no	9.318	9.296	EPSD	COSMIC	2.638	Down-regulation
CMGC_MAPK_JNK_MAPK8_ST	Q14934	NFATC4	P45983	MAPK8	T276	R270C	270	Missense	distal	-6	no	9.318	9.293	EPSD	COSMIC	2.638	Down-regulation
CMGC_MAPK_JNK_MAPK8_ST	Q14934	NFATC4	P45983	MAPK8	T276	S274L	274	Missense	proximal	-2	no	9.318	9.230	EPSD	COSMIC	2.638	Down-regulation
CMGC_MAPK_JNK_MAPK8_ST	Q14934	NFATC4	P45983	MAPK8	S279	G275S	275	Missense	distal	-4	no	1.833	2.722	EPSD	COSMIC	2.638	Gain
CMGC_MAPK_JNK_MAPK8_ST	Q14934	NFATC4	P45983	MAPK8	S281	R286W	286	Missense	distal	5	no	8.217	8.239	EPSD	COSMIC	2.638	Up-regulation
CMGC_MAPK_JNK_MAPK8_ST	Q14934	NFATC4	P45983	MAPK8	S281	P277Q	277	Missense	distal	-4	no	8.217	8.601	EPSD	COSMIC	2.638	Up-regulation
CMGC_MAPK_JNK_MAPK8_ST	Q14934	NFATC4	P45983	MAPK8	S281	S285P	285	Missense	distal	4	no	8.217	8.192	EPSD	COSMIC	2.638	Down-regulation
CMGC_MAPK_JNK_MAPK8_ST	Q14934	NFATC4	P45983	MAPK8	S281	G275S	275	Missense	distal	-6	no	8.217	8.066	EPSD	COSMIC	2.638	Down-regulation
CMGC_MAPK_JNK_MAPK8_ST	Q14934	NFATC4	P45983	MAPK8	S281	G288W	288	Missense	distal	7	no	8.217	8.229	EPSD	COSMIC	2.638	Up-regulation
CMGC_MAPK_JNK_MAPK8_ST	Q14934	NFATC4	P45983	MAPK8	S281	P282A	282	Missense	proximal	1	no	8.217	1.870	EPSD	COSMIC	2.638	Loss
CMGC_MAPK_JNK_MAPK8_ST	Q14934	NFATC4	P45983	MAPK8	S281	R286H	286	Missense	distal	5	no	8.217	8.196	EPSD	COSMIC	2.638	Down-regulation
CMGC_MAPK_JNK_MAPK8_ST	Q14934	NFATC4	P45983	MAPK8	S281	R287H	287	Missense	distal	6	no	8.217	8.230	EPSD	COSMIC	2.638	Up-regulation
CMGC_MAPK_JNK_MAPK8_ST	Q14934	NFATC4	P45983	MAPK8	S281	R287S	287	Missense	distal	6	no	8.217	8.277	EPSD	COSMIC	2.638	Up-regulation
CMGC_MAPK_JNK_MAPK8_ST	Q14934	NFATC4	P45983	MAPK8	S281	S281F	281	Missense	central	0	yes	8.217	0.000	EPSD	COSMIC	2.638	Loss
CMGC_MAPK_JNK_MAPK8_ST	Q14934	NFATC4	P45983	MAPK8	S281	S274L	274	Missense	distal	-7	no	8.217	8.235	EPSD	COSMIC	2.638	Up-regulation
CMGC_MAPK_JNK_MAPK8_ST	Q14934	NFATC4	P45983	MAPK8	S285	R286W	286	Missense	proximal	1	no	1.595	3.057	EPSD	COSMIC	2.638	Gain
CMGC_MAPK_JNK_MAPK8_ST	Q14934	NFATC4	P45983	MAPK8	S311	P314S	314	Missense	distal	3	no	6.901	6.775	EPSD	COSMIC	2.638	Down-regulation
CMGC_MAPK_JNK_MAPK8_ST	Q14934	NFATC4	P45983	MAPK8	S311	P312S	312	Missense	proximal	1	no	6.901	-0.828	EPSD	COSMIC	2.638	Loss
CMGC_MAPK_JNK_MAPK8_ST	Q14934	NFATC4	P45983	MAPK8	S311	P304L	304	Missense	distal	-7	no	6.901	6.912	EPSD	COSMIC	2.638	Up-regulation
CMGC_MAPK_JNK_MAPK8_ST	Q14934	NFATC4	P45983	MAPK8	S311	D316Y	316	Missense	distal	5	no	6.901	6.961	EPSD	COSMIC	2.638	Up-regulation
CMGC_MAPK_JNK_MAPK8_ST	Q14934	NFATC4	P45983	MAPK8	S311	F315L	315	Missense	distal	4	no	6.901	6.927	EPSD	COSMIC;CCLE	2.638	Up-regulation
CMGC_MAPK_JNK_MAPK8_ST	Q14934	NFATC4	P45983	MAPK8	S334	S335P	335	Missense	proximal	1	no	-0.656	7.073	EPSD	COSMIC	2.638	Gain
CMGC_MAPK_JNK_MAPK8_ST	Q14934	NFATC4	P45983	MAPK8	S382	D376N	376	Missense	distal	-6	no	7.994	8.077	EPSD	COSMIC	2.638	Up-regulation
CMGC_MAPK_JNK_MAPK8_ST	Q14934	NFATC4	P45983	MAPK8	S382	V380A	380	Missense	proximal	-2	no	7.994	8.185	EPSD	COSMIC	2.638	Up-regulation
CMGC_MAPK_JNK_MAPK8_ST	Q14934	NFATC4	P45983	MAPK8	S382	P383T	383	Missense	proximal	1	no	7.994	1.007	EPSD	COSMIC	2.638	Loss
CMGC_MAPK_JNK_MAPK8_ST	Q14934	NFATC4	P45983	MAPK8	S382	S387F	387	Missense	distal	5	no	7.994	8.070	EPSD	COSMIC	2.638	Up-regulation
CMGC_MAPK_JNK_MAPK8_ST	Q14934	NFATC4	P45983	MAPK8	S382	D376Y	376	Missense	distal	-6	no	7.994	8.133	EPSD	COSMIC	2.638	Up-regulation
CMGC_MAPK_JNK_MAPK8_ST	Q14934	NFATC4	P45983	MAPK8	S395	P396T	396	Missense	proximal	1	no	7.287	0.300	EPSD	COSMIC	2.638	Loss
CMGC_MAPK_JNK_MAPK8_ST	Q14934	NFATC4	P45983	MAPK8	S395	A402V	402	Missense	distal	7	no	7.287	7.366	EPSD	COSMIC	2.638	Up-regulation
CMGC_MAPK_JNK_MAPK8_ST	Q14934	NFATC4	P45983	MAPK8	S395	R399K	399	Missense	distal	4	no	7.287	7.682	EPSD	COSMIC	2.638	Up-regulation
CMGC_MAPK_JNK_MAPK8_ST	Q14934	NFATC4	P45983	MAPK8	S395	G392V	392	Missense	distal	-3	no	7.287	7.174	EPSD	COSMIC	2.638	Down-regulation
CMGC_MAPK_JNK_MAPK8_ST	Q14934	NFATC4	P45983	MAPK8	S395	F398S	398	Missense	distal	3	no	7.287	7.068	EPSD	COSMIC	2.638	Down-regulation
CMGC_MAPK_JNK_MAPK8_ST	Q14934	NFATC4	P45983	MAPK8	S395	I391T	391	Missense	distal	-4	no	7.287	7.714	EPSD	COSMIC	2.638	Up-regulation
CMGC_MAPK_JNK_MAPK8_ST	Q14934	NFATC4	P45983	MAPK8	S395	S395I	395	Missense	central	0	yes	7.287	0.000	EPSD	COSMIC	2.638	Loss
CMGC_MAPK_JNK_MAPK8_ST	Q14934	NFATC4	P45983	MAPK8	S532	L527I	527	Missense	distal	-5	no	3.877	3.609	EPSD	COSMIC	2.638	Down-regulation
CMGC_MAPK_JNK_MAPK8_ST	Q14934	NFATC4	P45983	MAPK8	S532	R530Q	530	Missense	proximal	-2	no	3.877	3.951	EPSD	COSMIC	2.638	Up-regulation
CMGC_MAPK_JNK_MAPK8_ST	Q14934	NFATC4	P45983	MAPK8	S532	R530W	530	Missense	proximal	-2	no	3.877	3.883	EPSD	COSMIC	2.638	Up-regulation
CMGC_MAPK_JNK_MAPK8_ST	Q14934	NFATC4	P45983	MAPK8	S532	E535K	535	Missense	distal	3	no	3.877	3.824	EPSD	COSMIC	2.638	Down-regulation
CMGC_MAPK_JNK_MAPK8_ST	Q14934	NFATC4	P45983	MAPK8	S532	R537Q	537	Missense	distal	5	no	3.877	3.825	EPSD	COSMIC	2.638	Down-regulation
CMGC_MAPK_JNK_MAPK8_ST	Q14934	NFATC4	P45983	MAPK8	S592	E589K	589	Missense	distal	-3	no	5.352	5.379	EPSD	COSMIC	2.638	Up-regulation
CMGC_MAPK_JNK_MAPK8_ST	Q14934	NFATC4	P45983	MAPK8	S592	S594L	594	Missense	proximal	2	no	5.352	5.091	EPSD	COSMIC	2.638	Down-regulation
CMGC_MAPK_JNK_MAPK8_ST	Q14934	NFATC4	P45983	MAPK8	S592	P586H	586	Missense	distal	-6	no	5.352	5.397	EPSD	COSMIC	2.638	Up-regulation
CMGC_MAPK_JNK_MAPK8_ST	Q14934	NFATC4	P45983	MAPK8	S592	P593S	593	Missense	proximal	1	no	5.352	-2.376	EPSD	COSMIC	2.638	Loss
CMGC_MAPK_JNK_MAPK8_ST	Q14934	NFATC4	P45983	MAPK8	S592	R599I	599	Missense	distal	7	no	5.352	5.330	EPSD	COSMIC	2.638	Down-regulation
CMGC_MAPK_JNK_MAPK8_ST	Q14934	NFATC4	P45983	MAPK8	S592	S594R	594	Missense	proximal	2	no	5.352	5.111	EPSD	COSMIC	2.638	Down-regulation
CMGC_MAPK_JNK_MAPK8_ST	Q14934	NFATC4	P45983	MAPK8	S676	P677A	677	Missense	proximal	1	no	7.656	1.309	EPSD	COSMIC	2.638	Loss
CMGC_MAPK_JNK_MAPK8_ST	Q14934	NFATC4	P45983	MAPK8	S676	S676N	676	Missense	central	0	yes	7.656	0.000	EPSD	COSMIC	2.638	Loss
CMGC_MAPK_JNK_MAPK8_ST	Q14934	NFATC4	P45983	MAPK8	S676	G671W	671	Missense	distal	-5	no	7.656	7.729	EPSD	COSMIC	2.638	Up-regulation
CMGC_MAPK_JNK_MAPK8_ST	Q14934	NFATC4	P45983	MAPK8	S676	R675H	675	Missense	proximal	-1	no	7.656	7.661	EPSD	COSMIC;CCLE	2.638	Up-regulation
CMGC_MAPK_JNK_MAPK8_ST	Q14934	NFATC4	P45983	MAPK8	S676	R672W	672	Missense	distal	-4	no	7.656	7.413	EPSD	COSMIC	2.638	Down-regulation
CMGC_MAPK_JNK_MAPK8_ST	Q14934	NFATC4	P45983	MAPK8	S676	G671R	671	Missense	distal	-5	no	7.656	7.684	EPSD	COSMIC	2.638	Up-regulation
CMGC_MAPK_JNK_MAPK8_ST	Q14934	NFATC4	P45983	MAPK8	S676	F683C	683	Missense	distal	7	no	7.656	7.633	EPSD	COSMIC	2.638	Down-regulation
CMGC_MAPK_JNK_MAPK8_ST	Q14934	NFATC4	P45983	MAPK8	S676	R675C	675	Missense	proximal	-1	no	7.656	7.662	EPSD	COSMIC	2.638	Up-regulation
CMGC_MAPK_JNK_MAPK8_ST	Q14934	NFATC4	P45983	MAPK8	S716	P723L	723	Missense	distal	7	no	8.381	8.421	EPSD	COSMIC	2.638	Up-regulation
CMGC_MAPK_JNK_MAPK8_ST	Q14934	NFATC4	P45983	MAPK8	S716	P721H	721	Missense	distal	5	no	8.381	8.349	EPSD	COSMIC	2.638	Down-regulation
CMGC_MAPK_JNK_MAPK8_ST	Q14934	NFATC4	P45983	MAPK8	S716	F709C	709	Missense	distal	-7	no	8.381	8.377	EPSD	COSMIC	2.638	Down-regulation
CMGC_MAPK_JNK_MAPK8_ST	Q14934	NFATC4	P45983	MAPK8	S716	R719K	719	Missense	distal	3	no	8.381	8.158	EPSD	COSMIC	2.638	Down-regulation
CMGC_MAPK_JNK_MAPK8_ST	Q14934	NFATC4	P45983	MAPK8	S716	P723S	723	Missense	distal	7	no	8.381	8.343	EPSD	COSMIC	2.638	Down-regulation
CMGC_MAPK_JNK_MAPK8_ST	Q14934	NFATC4	P45983	MAPK8	S819	G824C	824	Missense	distal	5	no	6.902	6.887	EPSD	COSMIC;CCLE	2.638	Down-regulation
CMGC_MAPK_JNK_MAPK8_ST	Q14934	NFATC4	P45983	MAPK8	S819	P817S	817	Missense	proximal	-2	no	6.902	6.796	EPSD	COSMIC	2.638	Down-regulation
CMGC_MAPK_JNK_MAPK8_ST	Q14934	NFATC4	P45983	MAPK8	S819	P820A	820	Missense	proximal	1	no	6.902	0.555	EPSD	COSMIC	2.638	Loss
CMGC_MAPK_JNK_MAPK8_ST	Q14934	NFATC4	P45983	MAPK8	S819	S819F	819	Missense	central	0	yes	6.902	0.000	EPSD	COSMIC	2.638	Loss
CMGC_MAPK_JNK_MAPK8_ST	Q14934	NFATC4	P45983	MAPK8	S819	A818V	818	Missense	proximal	-1	no	6.902	6.866	EPSD	COSMIC	2.638	Down-regulation
CMGC_MAPK_JNK_MAPK8_ST	Q14934	NFATC4	P45983	MAPK8	S819	A818S	818	Missense	proximal	-1	no	6.902	6.900	EPSD	COSMIC	2.638	Down-regulation
CMGC_MAPK_JNK_MAPK8_ST	Q14934	NFATC4	P45983	MAPK8	S819	P825S	825	Missense	distal	6	no	6.902	6.926	EPSD	COSMIC	2.638	Up-regulation
CMGC_MAPK_JNK_MAPK8_ST	Q14934	NFATC4	P45983	MAPK8	S819	P815H	815	Missense	distal	-4	no	6.902	6.824	EPSD	COSMIC	2.638	Down-regulation
CMGC_MAPK_JNK_MAPK8_ST	Q14934	NFATC4	P45983	MAPK8	S819	P813S	813	Missense	distal	-6	no	6.902	6.813	EPSD	COSMIC	2.638	Down-regulation
CMGC_MAPK_JNK_MAPK8_ST	Q14934	NFATC4	P45983	MAPK8	S819	E823A	823	Missense	distal	4	no	6.902	6.952	EPSD	COSMIC	2.638	Up-regulation
CMGC_MAPK_JNK_MAPK8_ST	Q14934	NFATC4	P45983	MAPK8	S819	R812W	812	Missense	distal	-7	no	6.902	6.905	EPSD	COSMIC	2.638	Up-regulation
CMGC_MAPK_JNK_MAPK8_ST	Q14934	NFATC4	P45983	MAPK8	S819	F826Y	826	Missense	distal	7	no	6.902	6.920	EPSD	COSMIC	2.638	Up-regulation
CMGC_MAPK_JNK_MAPK8_ST	Q14934	NFATC4	P45983	MAPK8	S819	P815S	815	Missense	distal	-4	no	6.902	7.567	EPSD	COSMIC	2.638	Up-regulation
CMGC_MAPK_JNK_MAPK8_ST	P17535	JUND	P45983	MAPK8	T71	A78T	78	Missense	distal	7	no	7.734	7.737	EPSD	COSMIC	2.638	Up-regulation
CMGC_MAPK_JNK_MAPK8_ST	P17535	JUND	P45983	MAPK8	S255	E254K	254	Missense	proximal	-1	no	6.957	6.959	EPSD	COSMIC	2.638	Up-regulation
CMGC_MAPK_JNK_MAPK8_ST	P17535	JUND	P45983	MAPK8	S259	E254K	254	Missense	distal	-5	no	8.532	8.456	EPSD	COSMIC	2.638	Down-regulation
CMGC_MAPK_JNK_MAPK8_ST	P17535	JUND	P45983	MAPK8	S315	L316M	316	Missense	proximal	1	no	2.657	2.369	EPSD	COSMIC	2.638	Loss
CMGC_MAPK_JNK_MAPK8_ST	P85298	ARHGAP8	P45983	MAPK8	T206	P209H	209	Missense	distal	3	no	8.983	9.021	EPSD	COSMIC	2.638	Up-regulation
CMGC_MAPK_JNK_MAPK8_ST	P85298	ARHGAP8	P45983	MAPK8	T206	R205Q	205	Missense	proximal	-1	no	8.983	9.003	EPSD	COSMIC	2.638	Up-regulation
CMGC_MAPK_JNK_MAPK8_ST	P85298	ARHGAP8	P45983	MAPK8	T206	H202Q	202	Missense	distal	-4	no	8.983	9.445	EPSD	COSMIC	2.638	Up-regulation
CMGC_MAPK_JNK_MAPK8_ST	P85298	ARHGAP8	P45983	MAPK8	T212	P209H	209	Missense	distal	-3	no	6.469	6.363	EPSD	COSMIC	2.638	Down-regulation
CMGC_MAPK_JNK_MAPK8_ST	P85298	ARHGAP8	P45983	MAPK8	T212	R205Q	205	Missense	distal	-7	no	6.469	6.459	EPSD	COSMIC	2.638	Down-regulation
CMGC_MAPK_JNK_MAPK8_ST	P85298	ARHGAP8	P45983	MAPK8	T212	P215S	215	Missense	distal	3	no	6.469	6.343	EPSD	COSMIC	2.638	Down-regulation
CMGC_MAPK_JNK_MAPK8_ST	P85298	ARHGAP8	P45983	MAPK8	T212	R216Q	216	Missense	distal	4	no	6.469	6.702	EPSD	COSMIC	2.638	Up-regulation
CMGC_MAPK_JNK_MAPK8_ST	P85298	ARHGAP8	P45983	MAPK8	S455	L452Q	452	Missense	distal	-3	no	8.633	8.869	PhosphoSitePlus	COSMIC	2.638	Up-regulation
CMGC_MAPK_JNK_MAPK8_ST	P85298	ARHGAP8	P45983	MAPK8	S455	P453T	453	Missense	proximal	-2	no	8.633	8.553	PhosphoSitePlus	COSMIC	2.638	Down-regulation
CMGC_MAPK_JNK_MAPK8_ST	P10415	BCL2	P45983	MAPK8	T56	F49C	49	Missense	distal	-7	no	9.128	9.123	EPSD	COSMIC	2.638	Down-regulation
CMGC_MAPK_JNK_MAPK8_ST	P10415	BCL2	P45983	MAPK8	T56	S51Y	51	Missense	distal	-5	no	9.128	9.728	EPSD	COSMIC	2.638	Up-regulation
CMGC_MAPK_JNK_MAPK8_ST	P10415	BCL2	P45983	MAPK8	T56	P57S	57	Missense	proximal	1	no	9.128	1.399	EPSD	COSMIC	2.638	Loss
CMGC_MAPK_JNK_MAPK8_ST	P10415	BCL2	P45983	MAPK8	T56	F49S	49	Missense	distal	-7	no	9.128	9.112	EPSD	COSMIC	2.638	Down-regulation
CMGC_MAPK_JNK_MAPK8_ST	P10415	BCL2	P45983	MAPK8	T56	H58L	58	Missense	proximal	2	no	9.128	9.049	EPSD	COSMIC	2.638	Down-regulation
CMGC_MAPK_JNK_MAPK8_ST	P10415	BCL2	P45983	MAPK8	T56	Q52P	52	Missense	distal	-4	no	9.128	8.744	EPSD	COSMIC	2.638	Down-regulation
CMGC_MAPK_JNK_MAPK8_ST	P10415	BCL2	P45983	MAPK8	T56	S51P	51	Missense	distal	-5	no	9.128	9.239	EPSD	COSMIC	2.638	Up-regulation
CMGC_MAPK_JNK_MAPK8_ST	P10415	BCL2	P45983	MAPK8	T56	S50P	50	Missense	distal	-6	no	9.128	9.217	EPSD	COSMIC	2.638	Up-regulation
CMGC_MAPK_JNK_MAPK8_ST	P10415	BCL2	P45983	MAPK8	T56	H58R	58	Missense	proximal	2	no	9.128	9.070	EPSD	COSMIC	2.638	Down-regulation
CMGC_MAPK_JNK_MAPK8_ST	P10415	BCL2	P45983	MAPK8	T56	A60G	60	Missense	distal	4	no	9.128	8.785	EPSD	COSMIC	2.638	Down-regulation
CMGC_MAPK_JNK_MAPK8_ST	P10415	BCL2	P45983	MAPK8	T56	P57L	57	Missense	proximal	1	no	9.128	1.555	EPSD	COSMIC	2.638	Loss
CMGC_MAPK_JNK_MAPK8_ST	P10415	BCL2	P45983	MAPK8	T56	A60D	60	Missense	distal	4	no	9.128	8.926	EPSD	COSMIC	2.638	Down-regulation
CMGC_MAPK_JNK_MAPK8_ST	P10415	BCL2	P45983	MAPK8	T56	Q52H	52	Missense	distal	-4	no	9.128	8.665	EPSD	COSMIC	2.638	Down-regulation
CMGC_MAPK_JNK_MAPK8_ST	P10415	BCL2	P45983	MAPK8	T56	P57A	57	Missense	proximal	1	no	9.128	2.780	EPSD	COSMIC	2.638	Down-regulation
CMGC_MAPK_JNK_MAPK8_ST	P10415	BCL2	P45983	MAPK8	S70	T74N	74	Missense	distal	4	no	7.351	6.952	PhosphoSitePlus;EPSD	COSMIC	2.638	Down-regulation
CMGC_MAPK_JNK_MAPK8_ST	P10415	BCL2	P45983	MAPK8	S70	T69A	69	Missense	proximal	-1	no	7.351	7.352	PhosphoSitePlus;EPSD	COSMIC	2.638	Up-regulation
CMGC_MAPK_JNK_MAPK8_ST	P10415	BCL2	P45983	MAPK8	S70	A67V	67	Missense	distal	-3	no	7.351	6.922	PhosphoSitePlus;EPSD	COSMIC	2.638	Down-regulation
CMGC_MAPK_JNK_MAPK8_ST	P10415	BCL2	P45983	MAPK8	S70	P65S	65	Missense	distal	-5	no	7.351	7.239	PhosphoSitePlus;EPSD	COSMIC	2.638	Down-regulation
CMGC_MAPK_JNK_MAPK8_ST	P10415	BCL2	P45983	MAPK8	S70	A77V	77	Missense	distal	7	no	7.351	7.430	PhosphoSitePlus;EPSD	COSMIC	2.638	Up-regulation
CMGC_MAPK_JNK_MAPK8_ST	P10415	BCL2	P45983	MAPK8	S70	P71S	71	Missense	proximal	1	no	7.351	-0.378	PhosphoSitePlus;EPSD	COSMIC	2.638	Loss
CMGC_MAPK_JNK_MAPK8_ST	P10415	BCL2	P45983	MAPK8	S70	D64G	64	Missense	distal	-6	no	7.351	7.409	PhosphoSitePlus;EPSD	COSMIC	2.638	Up-regulation
CMGC_MAPK_JNK_MAPK8_ST	P10415	BCL2	P45983	MAPK8	S70	A76S	76	Missense	distal	6	no	7.351	7.354	PhosphoSitePlus;EPSD	COSMIC	2.638	Up-regulation
CMGC_MAPK_JNK_MAPK8_ST	P10415	BCL2	P45983	MAPK8	S70	T74A	74	Missense	distal	4	no	7.351	7.399	PhosphoSitePlus;EPSD	COSMIC	2.638	Up-regulation
CMGC_MAPK_JNK_MAPK8_ST	P10415	BCL2	P45983	MAPK8	S70	T74I	74	Missense	distal	4	no	7.351	7.210	PhosphoSitePlus;EPSD	COSMIC	2.638	Down-regulation
CMGC_MAPK_JNK_MAPK8_ST	P10415	BCL2	P45983	MAPK8	S70	T69P	69	Missense	proximal	-1	no	7.351	7.340	PhosphoSitePlus;EPSD	COSMIC;CCLE	2.638	Down-regulation
CMGC_MAPK_JNK_MAPK8_ST	P10415	BCL2	P45983	MAPK8	S70	V66I	66	Missense	distal	-4	no	7.351	7.743	PhosphoSitePlus;EPSD	COSMIC	2.638	Up-regulation
CMGC_MAPK_JNK_MAPK8_ST	P10415	BCL2	P45983	MAPK8	S70	P65Q	65	Missense	distal	-5	no	7.351	7.328	PhosphoSitePlus;EPSD	COSMIC	2.638	Down-regulation
CMGC_MAPK_JNK_MAPK8_ST	P10415	BCL2	P45983	MAPK8	T74	T74N	74	Missense	central	0	yes	9.142	0.000	EPSD	COSMIC	2.638	Loss
CMGC_MAPK_JNK_MAPK8_ST	P10415	BCL2	P45983	MAPK8	T74	T69A	69	Missense	distal	-5	no	9.142	9.126	EPSD	COSMIC	2.638	Down-regulation
CMGC_MAPK_JNK_MAPK8_ST	P10415	BCL2	P45983	MAPK8	T74	A67V	67	Missense	distal	-7	no	9.142	9.160	EPSD	COSMIC	2.638	Up-regulation
CMGC_MAPK_JNK_MAPK8_ST	P10415	BCL2	P45983	MAPK8	T74	A76T	76	Missense	proximal	2	no	9.142	9.121	EPSD	COSMIC	2.638	Down-regulation
CMGC_MAPK_JNK_MAPK8_ST	P10415	BCL2	P45983	MAPK8	T74	A77V	77	Missense	distal	3	no	9.142	9.370	EPSD	COSMIC	2.638	Up-regulation
CMGC_MAPK_JNK_MAPK8_ST	P10415	BCL2	P45983	MAPK8	T74	P71S	71	Missense	distal	-3	no	9.142	9.304	EPSD	COSMIC	2.638	Up-regulation
CMGC_MAPK_JNK_MAPK8_ST	P10415	BCL2	P45983	MAPK8	T74	A76S	76	Missense	proximal	2	no	9.142	9.118	EPSD	COSMIC	2.638	Down-regulation
CMGC_MAPK_JNK_MAPK8_ST	P10415	BCL2	P45983	MAPK8	T74	T74A	74	Missense	central	0	yes	9.142	0.000	EPSD	COSMIC	2.638	Loss
CMGC_MAPK_JNK_MAPK8_ST	P10415	BCL2	P45983	MAPK8	T74	A80V	80	Missense	distal	6	no	9.142	9.067	EPSD	COSMIC	2.638	Down-regulation
CMGC_MAPK_JNK_MAPK8_ST	P10415	BCL2	P45983	MAPK8	T74	T74I	74	Missense	central	0	yes	9.142	0.000	EPSD	COSMIC	2.638	Loss
CMGC_MAPK_JNK_MAPK8_ST	P10415	BCL2	P45983	MAPK8	T74	T69P	69	Missense	distal	-5	no	9.142	9.254	EPSD	COSMIC;CCLE	2.638	Up-regulation
CMGC_MAPK_JNK_MAPK8_ST	P10415	BCL2	P45983	MAPK8	S87	L86F	86	Missense	proximal	-1	no	7.709	7.708	EPSD;PhosphoSitePlus	COSMIC	2.638	Down-regulation
CMGC_MAPK_JNK_MAPK8_ST	P10415	BCL2	P45983	MAPK8	S87	A85V	85	Missense	proximal	-2	no	7.709	7.518	EPSD;PhosphoSitePlus	COSMIC	2.638	Down-regulation
CMGC_MAPK_JNK_MAPK8_ST	P10415	BCL2	P45983	MAPK8	S87	P91S	91	Missense	distal	4	no	7.709	7.734	EPSD;PhosphoSitePlus	COSMIC;GDSC;CCLE	2.638	Up-regulation
CMGC_MAPK_JNK_MAPK8_ST	P10415	BCL2	P45983	MAPK8	S87	G83E	83	Missense	distal	-4	no	7.709	8.454	EPSD;PhosphoSitePlus	COSMIC	2.638	Up-regulation
CMGC_MAPK_JNK_MAPK8_ST	P10415	BCL2	P45983	MAPK8	S87	P91A	91	Missense	distal	4	no	7.709	7.733	EPSD;PhosphoSitePlus	COSMIC	2.638	Up-regulation
CMGC_MAPK_JNK_MAPK8_ST	P10415	BCL2	P45983	MAPK8	S87	P90T	90	Missense	distal	3	no	7.709	7.611	EPSD;PhosphoSitePlus	COSMIC	2.638	Down-regulation
CMGC_MAPK_JNK_MAPK8_ST	P10415	BCL2	P45983	MAPK8	S87	H94Y	94	Missense	distal	7	no	7.709	7.750	EPSD;PhosphoSitePlus	COSMIC	2.638	Up-regulation
CMGC_MAPK_JNK_MAPK8_ST	P10415	BCL2	P45983	MAPK8	S87	A85T	85	Missense	proximal	-2	no	7.709	7.679	EPSD;PhosphoSitePlus	COSMIC	2.638	Down-regulation
CMGC_MAPK_JNK_MAPK8_ST	P10415	BCL2	P45983	MAPK8	S87	V93L	93	Missense	distal	6	no	7.709	7.716	EPSD;PhosphoSitePlus	COSMIC	2.638	Up-regulation
CMGC_MAPK_JNK_MAPK8_ST	P10415	BCL2	P45983	MAPK8	S87	P91L	91	Missense	distal	4	no	7.709	7.302	EPSD;PhosphoSitePlus	COSMIC	2.638	Down-regulation
CMGC_MAPK_JNK_MAPK8_ST	P10415	BCL2	P45983	MAPK8	S87	S87N	87	Missense	central	0	yes	7.709	0.000	EPSD;PhosphoSitePlus	COSMIC	2.638	Loss
CMGC_MAPK_JNK_MAPK8_ST	P10415	BCL2	P45983	MAPK8	S87	A80V	80	Missense	distal	-7	no	7.709	7.727	EPSD;PhosphoSitePlus	COSMIC	2.638	Up-regulation
CMGC_MAPK_JNK_MAPK8_ST	Q9Y6Q9	NCOA3	P45983	MAPK8	S13	A12T	12	Missense	proximal	-1	no	3.637	3.636	EPSD	COSMIC	2.638	Down-regulation
CMGC_MAPK_JNK_MAPK8_ST	Q9Y6Q9	NCOA3	P45983	MAPK8	S13	R18C	18	Missense	distal	5	no	3.637	3.619	EPSD	COSMIC	2.638	Down-regulation
CMGC_MAPK_JNK_MAPK8_ST	Q9Y6Q9	NCOA3	P45983	MAPK8	S13	K19R	19	Missense	distal	6	no	3.637	3.559	EPSD	COSMIC	2.638	Down-regulation
CMGC_MAPK_JNK_MAPK8_ST	Q9Y6Q9	NCOA3	P45983	MAPK8	S13	L20W	20	Missense	distal	7	no	3.637	3.636	EPSD	COSMIC	2.638	Down-regulation
CMGC_MAPK_JNK_MAPK8_ST	Q9Y6Q9	NCOA3	P45983	MAPK8	T24	R18C	18	Missense	distal	-6	no	6.817	6.792	EPSD;PhosphoSitePlus	COSMIC	2.638	Down-regulation
CMGC_MAPK_JNK_MAPK8_ST	Q9Y6Q9	NCOA3	P45983	MAPK8	T24	K19R	19	Missense	distal	-5	no	6.817	7.316	EPSD;PhosphoSitePlus	COSMIC	2.638	Up-regulation
CMGC_MAPK_JNK_MAPK8_ST	Q9Y6Q9	NCOA3	P45983	MAPK8	T24	L20W	20	Missense	distal	-4	no	6.817	6.764	EPSD;PhosphoSitePlus	COSMIC	2.638	Down-regulation
CMGC_MAPK_JNK_MAPK8_ST	Q9Y6Q9	NCOA3	P45983	MAPK8	T203	E209K	209	Missense	distal	6	no	7.504	7.521	EPSD	COSMIC	2.638	Up-regulation
CMGC_MAPK_JNK_MAPK8_ST	Q9Y6Q9	NCOA3	P45983	MAPK8	T203	N196H	196	Missense	distal	-7	no	7.504	7.501	EPSD	COSMIC	2.638	Down-regulation
CMGC_MAPK_JNK_MAPK8_ST	Q9Y6Q9	NCOA3	P45983	MAPK8	T203	T203A	203	Missense	central	0	yes	7.504	0.000	EPSD	COSMIC	2.638	Loss
CMGC_MAPK_JNK_MAPK8_ST	Q9Y6Q9	NCOA3	P45983	MAPK8	T203	E209D	209	Missense	distal	6	no	7.504	7.469	EPSD	COSMIC	2.638	Down-regulation
CMGC_MAPK_JNK_MAPK8_ST	Q9Y6Q9	NCOA3	P45983	MAPK8	T203	H205R	205	Missense	proximal	2	no	7.504	7.446	EPSD	COSMIC	2.638	Down-regulation
CMGC_MAPK_JNK_MAPK8_ST	Q9Y6Q9	NCOA3	P45983	MAPK8	T203	C197R	197	Missense	distal	-6	no	7.504	7.530	EPSD	COSMIC	2.638	Up-regulation
CMGC_MAPK_JNK_MAPK8_ST	Q9Y6Q9	NCOA3	P45983	MAPK8	S214	R218C	218	Missense	distal	4	no	7.609	7.642	EPSD	COSMIC	2.638	Up-regulation
CMGC_MAPK_JNK_MAPK8_ST	Q9Y6Q9	NCOA3	P45983	MAPK8	S214	E209K	209	Missense	distal	-5	no	7.609	7.532	EPSD	COSMIC	2.638	Down-regulation
CMGC_MAPK_JNK_MAPK8_ST	Q9Y6Q9	NCOA3	P45983	MAPK8	S214	R218H	218	Missense	distal	4	no	7.609	7.646	EPSD	COSMIC	2.638	Up-regulation
CMGC_MAPK_JNK_MAPK8_ST	Q9Y6Q9	NCOA3	P45983	MAPK8	S214	M217I	217	Missense	distal	3	no	7.609	7.527	EPSD	COSMIC	2.638	Down-regulation
CMGC_MAPK_JNK_MAPK8_ST	Q9Y6Q9	NCOA3	P45983	MAPK8	S214	Y221H	221	Missense	distal	7	no	7.609	7.568	EPSD	COSMIC	2.638	Down-regulation
CMGC_MAPK_JNK_MAPK8_ST	Q9Y6Q9	NCOA3	P45983	MAPK8	S214	A213T	213	Missense	proximal	-1	no	7.609	7.608	EPSD	COSMIC;GDSC	2.638	Down-regulation
CMGC_MAPK_JNK_MAPK8_ST	Q9Y6Q9	NCOA3	P45983	MAPK8	S214	E209D	209	Missense	distal	-5	no	7.609	7.851	EPSD	COSMIC	2.638	Up-regulation
CMGC_MAPK_JNK_MAPK8_ST	Q9Y6Q9	NCOA3	P45983	MAPK8	S423	Q427H	427	Missense	distal	4	no	2.882	2.686	EPSD	COSMIC	2.638	Down-regulation
CMGC_MAPK_JNK_MAPK8_ST	Q9Y6Q9	NCOA3	P45983	MAPK8	S423	P422A	422	Missense	proximal	-1	no	2.882	2.894	EPSD	COSMIC	2.638	Up-regulation
CMGC_MAPK_JNK_MAPK8_ST	Q9Y6Q9	NCOA3	P45983	MAPK8	S450	S452P	452	Missense	proximal	2	no	8.052	7.867	EPSD	COSMIC;GDSC;CCLE	2.638	Down-regulation
CMGC_MAPK_JNK_MAPK8_ST	Q9Y6Q9	NCOA3	P45983	MAPK8	S465	N462S	462	Missense	distal	-3	no	7.105	7.458	EPSD	COSMIC	2.638	Up-regulation
CMGC_MAPK_JNK_MAPK8_ST	Q9Y6Q9	NCOA3	P45983	MAPK8	S465	G460E	460	Missense	distal	-5	no	7.105	6.711	EPSD	COSMIC	2.638	Down-regulation
CMGC_MAPK_JNK_MAPK8_ST	Q9Y6Q9	NCOA3	P45983	MAPK8	S465	G469W	469	Missense	distal	4	no	7.105	7.056	EPSD	COSMIC	2.638	Down-regulation
CMGC_MAPK_JNK_MAPK8_ST	Q9Y6Q9	NCOA3	P45983	MAPK8	S465	P471H	471	Missense	distal	6	no	7.105	7.082	EPSD	COSMIC	2.638	Down-regulation
CMGC_MAPK_JNK_MAPK8_ST	Q9Y6Q9	NCOA3	P45983	MAPK8	S470	G469W	469	Missense	proximal	-1	no	8.539	8.535	EPSD	COSMIC	2.638	Down-regulation
CMGC_MAPK_JNK_MAPK8_ST	Q9Y6Q9	NCOA3	P45983	MAPK8	S470	P471H	471	Missense	proximal	1	no	8.539	0.624	EPSD	COSMIC	2.638	Loss
CMGC_MAPK_JNK_MAPK8_ST	Q9Y6Q9	NCOA3	P45983	MAPK8	S505	P499L	499	Missense	distal	-6	no	8.149	8.240	EPSD;PhosphoSitePlus	COSMIC;GDSC;CCLE	2.638	Up-regulation
CMGC_MAPK_JNK_MAPK8_ST	Q9Y6Q9	NCOA3	P45983	MAPK8	S505	V503M	503	Missense	proximal	-2	no	8.149	8.194	EPSD;PhosphoSitePlus	COSMIC	2.638	Up-regulation
CMGC_MAPK_JNK_MAPK8_ST	Q9Y6Q9	NCOA3	P45983	MAPK8	S505	H504Y	504	Missense	proximal	-1	no	8.149	8.132	EPSD;PhosphoSitePlus	COSMIC	2.638	Down-regulation
CMGC_MAPK_JNK_MAPK8_ST	Q9Y6Q9	NCOA3	P45983	MAPK8	S505	A508T	508	Missense	distal	3	no	8.149	8.159	EPSD;PhosphoSitePlus	COSMIC;GDSC;CCLE	2.638	Up-regulation
CMGC_MAPK_JNK_MAPK8_ST	Q9Y6Q9	NCOA3	P45983	MAPK8	S543	K547T	547	Missense	distal	4	no	9.869	9.790	EPSD;PhosphoSitePlus	COSMIC	2.638	Down-regulation
CMGC_MAPK_JNK_MAPK8_ST	Q9Y6Q9	NCOA3	P45983	MAPK8	S543	S543P	543	Missense	central	0	yes	9.869	0.000	EPSD;PhosphoSitePlus	COSMIC	2.638	Loss
CMGC_MAPK_JNK_MAPK8_ST	Q9Y6Q9	NCOA3	P45983	MAPK8	S543	D549N	549	Missense	distal	6	no	9.869	9.838	EPSD;PhosphoSitePlus	COSMIC	2.638	Down-regulation
CMGC_MAPK_JNK_MAPK8_ST	Q9Y6Q9	NCOA3	P45983	MAPK8	S551	K547T	547	Missense	distal	-4	no	6.839	6.513	EPSD	COSMIC	2.638	Down-regulation
CMGC_MAPK_JNK_MAPK8_ST	Q9Y6Q9	NCOA3	P45983	MAPK8	S551	D549N	549	Missense	proximal	-2	no	6.839	6.742	EPSD	COSMIC	2.638	Down-regulation
CMGC_MAPK_JNK_MAPK8_ST	Q9Y6Q9	NCOA3	P45983	MAPK8	S569	D576N	576	Missense	distal	7	no	8.341	8.370	EPSD	COSMIC	2.638	Up-regulation
CMGC_MAPK_JNK_MAPK8_ST	Q9Y6Q9	NCOA3	P45983	MAPK8	S569	D566Y	566	Missense	distal	-3	no	8.341	8.045	EPSD	COSMIC	2.638	Down-regulation
CMGC_MAPK_JNK_MAPK8_ST	Q9Y6Q9	NCOA3	P45983	MAPK8	S569	N564S	564	Missense	distal	-5	no	8.341	7.910	EPSD	COSMIC	2.638	Down-regulation
CMGC_MAPK_JNK_MAPK8_ST	Q9Y6Q9	NCOA3	P45983	MAPK8	S640	S636F	636	Missense	distal	-4	no	8.093	7.155	EPSD	COSMIC	2.638	Down-regulation
CMGC_MAPK_JNK_MAPK8_ST	Q9Y6Q9	NCOA3	P45983	MAPK8	S655	E648K	648	Missense	distal	-7	no	6.793	6.789	EPSD	COSMIC	2.638	Down-regulation
CMGC_MAPK_JNK_MAPK8_ST	Q9Y6Q9	NCOA3	P45983	MAPK8	S694	I701L	701	Missense	distal	7	no	7.525	7.563	EPSD	COSMIC	2.638	Up-regulation
CMGC_MAPK_JNK_MAPK8_ST	Q9Y6Q9	NCOA3	P45983	MAPK8	S694	A696S	696	Missense	proximal	2	no	7.525	7.501	EPSD	COSMIC	2.638	Down-regulation
CMGC_MAPK_JNK_MAPK8_ST	Q9Y6Q9	NCOA3	P45983	MAPK8	S694	L689P	689	Missense	distal	-5	no	7.525	7.165	EPSD	COSMIC	2.638	Down-regulation
CMGC_MAPK_JNK_MAPK8_ST	Q9Y6Q9	NCOA3	P45983	MAPK8	S694	L688V	688	Missense	distal	-6	no	7.525	7.550	EPSD	COSMIC	2.638	Up-regulation
CMGC_MAPK_JNK_MAPK8_ST	Q9Y6Q9	NCOA3	P45983	MAPK8	T706	I701L	701	Missense	distal	-5	no	2.442	2.710	EPSD	COSMIC	2.638	Gain
CMGC_MAPK_JNK_MAPK8_ST	Q9Y6Q9	NCOA3	P45983	MAPK8	S728	Q726H	726	Missense	proximal	-2	no	9.493	9.419	EPSD	COSMIC	2.638	Down-regulation
CMGC_MAPK_JNK_MAPK8_ST	Q9Y6Q9	NCOA3	P45983	MAPK8	S860	S867C	867	Missense	distal	7	no	9.080	9.133	EPSD;PhosphoSitePlus	COSMIC	2.638	Up-regulation
CMGC_MAPK_JNK_MAPK8_ST	Q9Y6Q9	NCOA3	P45983	MAPK8	S860	S863F	863	Missense	distal	3	no	9.080	9.300	EPSD;PhosphoSitePlus	COSMIC	2.638	Up-regulation
CMGC_MAPK_JNK_MAPK8_ST	Q9Y6Q9	NCOA3	P45983	MAPK8	S860	G865D	865	Missense	distal	5	no	9.080	9.059	EPSD;PhosphoSitePlus	COSMIC	2.638	Down-regulation
CMGC_MAPK_JNK_MAPK8_ST	Q9Y6Q9	NCOA3	P45983	MAPK8	S860	S857C	857	Missense	distal	-3	no	9.080	8.825	EPSD;PhosphoSitePlus	COSMIC	2.638	Down-regulation
CMGC_MAPK_JNK_MAPK8_ST	Q9Y6Q9	NCOA3	P45983	MAPK8	S867	S867C	867	Missense	central	0	yes	9.296	0.000	PhosphoSitePlus;EPSD	COSMIC	2.638	Loss
CMGC_MAPK_JNK_MAPK8_ST	Q9Y6Q9	NCOA3	P45983	MAPK8	S867	S863F	863	Missense	distal	-4	no	9.296	8.358	PhosphoSitePlus;EPSD	COSMIC	2.638	Down-regulation
CMGC_MAPK_JNK_MAPK8_ST	Q9Y6Q9	NCOA3	P45983	MAPK8	S867	G865D	865	Missense	proximal	-2	no	9.296	9.341	PhosphoSitePlus;EPSD	COSMIC	2.638	Up-regulation
CMGC_MAPK_JNK_MAPK8_ST	Q9Y6Q9	NCOA3	P45983	MAPK8	T914	D919V	919	Missense	distal	5	no	8.452	8.486	EPSD	COSMIC	2.638	Up-regulation
CMGC_MAPK_JNK_MAPK8_ST	Q9Y6Q9	NCOA3	P45983	MAPK8	T914	W920R	920	Missense	distal	6	no	8.452	8.461	EPSD	COSMIC	2.638	Up-regulation
CMGC_MAPK_JNK_MAPK8_ST	Q9Y6Q9	NCOA3	P45983	MAPK8	S1330	S1330G	1330	Missense	central	0	yes	8.361	0.000	EPSD	COSMIC	2.638	Loss
CMGC_MAPK_JNK_MAPK8_ST	Q9Y6Q9	NCOA3	P45983	MAPK8	S1330	P1331L	1331	Missense	proximal	1	no	8.361	0.788	EPSD	COSMIC	2.638	Loss
CMGC_MAPK_JNK_MAPK8_ST	Q15672	TWIST1	P45983	MAPK8	S8	S11L	11	Missense	distal	3	no	6.935	7.163	EPSD	COSMIC	2.638	Up-regulation
CMGC_MAPK_JNK_MAPK8_ST	Q15672	TWIST1	P45983	MAPK8	S11	S11L	11	Missense	central	0	yes	8.307	0.000	EPSD	COSMIC	2.638	Loss
CMGC_MAPK_JNK_MAPK8_ST	Q15672	TWIST1	P45983	MAPK8	S68	R74S	74	Missense	distal	6	no	8.688	8.748	PhosphoSitePlus	COSMIC	2.638	Up-regulation
CMGC_MAPK_JNK_MAPK8_ST	Q15672	TWIST1	P45983	MAPK8	S68	P66A	66	Missense	proximal	-2	no	8.688	8.638	PhosphoSitePlus	COSMIC	2.638	Down-regulation
CMGC_MAPK_JNK_MAPK8_ST	Q15672	TWIST1	P45983	MAPK8	S95	P100S	100	Missense	distal	5	no	3.031	2.948	EPSD	COSMIC	2.638	Down-regulation
CMGC_MAPK_JNK_MAPK8_ST	Q15672	TWIST1	P45983	MAPK8	S99	E104K	104	Missense	distal	5	no	8.122	8.113	EPSD	COSMIC	2.638	Down-regulation
CMGC_MAPK_JNK_MAPK8_ST	Q15672	TWIST1	P45983	MAPK8	S99	P100S	100	Missense	proximal	1	no	8.122	0.393	EPSD	COSMIC	2.638	Loss
CMGC_MAPK_JNK_MAPK8_ST	Q9NR28	DIABLO	P45983	MAPK8	S6	V12L	12	Missense	distal	6	no	3.765	3.772	EPSD;PhosphoSitePlus	COSMIC	2.638	Up-regulation
CMGC_MAPK_JNK_MAPK8_ST	Q9NR28	DIABLO	P45983	MAPK8	S6	W7R	7	Missense	proximal	1	no	3.765	2.302	EPSD;PhosphoSitePlus	COSMIC	2.638	Loss
CMGC_MAPK_JNK_MAPK8_ST	Q9NR28	DIABLO	P45983	MAPK8	S9	V12L	12	Missense	distal	3	no	2.968	2.949	PhosphoSitePlus;EPSD	COSMIC	2.638	Down-regulation
CMGC_MAPK_JNK_MAPK8_ST	Q9NR28	DIABLO	P45983	MAPK8	S9	W7R	7	Missense	proximal	-2	no	2.968	2.962	PhosphoSitePlus;EPSD	COSMIC	2.638	Down-regulation
CMGC_MAPK_JNK_MAPK8_ST	Q9UGP4	LIMD1	P45983	MAPK8	S187	W190R	190	Missense	distal	3	no	7.606	7.556	EPSD	COSMIC	2.638	Down-regulation
CMGC_MAPK_JNK_MAPK8_ST	Q9UGP4	LIMD1	P45983	MAPK8	S197	S197F	197	Missense	central	0	yes	8.126	0.000	EPSD	COSMIC	2.638	Loss
CMGC_MAPK_JNK_MAPK8_ST	Q9UGP4	LIMD1	P45983	MAPK8	S197	W190R	190	Missense	distal	-7	no	8.126	8.122	EPSD	COSMIC	2.638	Down-regulation
CMGC_MAPK_JNK_MAPK8_ST	Q9UGP4	LIMD1	P45983	MAPK8	S197	S199R	199	Missense	proximal	2	no	8.126	7.884	EPSD	COSMIC	2.638	Down-regulation
CMGC_MAPK_JNK_MAPK8_ST	Q9UGP4	LIMD1	P45983	MAPK8	S211	P209L	209	Missense	proximal	-2	no	8.655	8.462	EPSD	COSMIC	2.638	Down-regulation
CMGC_MAPK_JNK_MAPK8_ST	Q9UGP4	LIMD1	P45983	MAPK8	T260	R254C	254	Missense	distal	-6	no	2.882	2.857	EPSD	COSMIC	2.638	Down-regulation
CMGC_MAPK_JNK_MAPK8_ST	Q9UGP4	LIMD1	P45983	MAPK8	T260	R254L	254	Missense	distal	-6	no	2.882	2.907	EPSD	COSMIC	2.638	Up-regulation
CMGC_MAPK_JNK_MAPK8_ST	Q9UGP4	LIMD1	P45983	MAPK8	T294	V287L	287	Missense	distal	-7	no	7.586	7.584	EPSD	COSMIC	2.638	Down-regulation
CMGC_MAPK_JNK_MAPK8_ST	Q9UGP4	LIMD1	P45983	MAPK8	S353	G359S	359	Missense	distal	6	no	8.411	8.468	EPSD	COSMIC;GDSC;CCLE	2.638	Up-regulation
CMGC_MAPK_JNK_MAPK8_ST	Q9UGP4	LIMD1	P45983	MAPK8	S353	G356D	356	Missense	distal	3	no	8.411	8.342	EPSD	COSMIC;GDSC;CCLE	2.638	Down-regulation
CMGC_MAPK_JNK_MAPK8_ST	Q9UGP4	LIMD1	P45983	MAPK8	S384	G378D	378	Missense	distal	-6	no	6.588	6.530	EPSD	COSMIC;GDSC;CCLE	2.638	Down-regulation
CMGC_MAPK_JNK_MAPK8_ST	Q9UGP4	LIMD1	P45983	MAPK8	S421	S424F	424	Missense	distal	3	no	6.910	7.129	EPSD;PhosphoSitePlus	COSMIC	2.638	Up-regulation
CMGC_MAPK_JNK_MAPK8_ST	Q9UGP4	LIMD1	P45983	MAPK8	S421	G415R	415	Missense	distal	-6	no	6.910	6.914	EPSD;PhosphoSitePlus	COSMIC;GDSC	2.638	Up-regulation
CMGC_MAPK_JNK_MAPK8_ST	Q9UGP4	LIMD1	P45983	MAPK8	S424	S424F	424	Missense	central	0	yes	8.533	0.000	EPSD;PhosphoSitePlus	COSMIC	2.638	Loss
CMGC_MAPK_JNK_MAPK8_ST	P35222	CTNNB1	P45983	MAPK8	S23	H24Y	24	Missense	proximal	1	no	1.826	3.096	EPSD	COSMIC	2.638	Gain
CMGC_MAPK_JNK_MAPK8_ST	P35222	CTNNB1	P45983	MAPK8	S33	A39G	39	Missense	distal	6	no	2.673	2.619	EPSD;PhosphoSitePlus	COSMIC	2.638	Loss
CMGC_MAPK_JNK_MAPK8_ST	P35222	CTNNB1	P45983	MAPK8	S33	G38A	38	Missense	distal	5	no	2.673	2.613	EPSD;PhosphoSitePlus	COSMIC	2.638	Loss
CMGC_MAPK_JNK_MAPK8_ST	P35222	CTNNB1	P45983	MAPK8	S33	T40I	40	Missense	distal	7	no	2.673	2.706	EPSD;PhosphoSitePlus	COSMIC	2.638	Up-regulation
CMGC_MAPK_JNK_MAPK8_ST	P35222	CTNNB1	P45983	MAPK8	S33	I35T	35	Missense	proximal	2	no	2.673	2.799	EPSD;PhosphoSitePlus	COSMIC	2.638	Up-regulation
CMGC_MAPK_JNK_MAPK8_ST	P35222	CTNNB1	P45983	MAPK8	S33	Q28E	28	Missense	distal	-5	no	2.673	2.566	EPSD;PhosphoSitePlus	COSMIC	2.638	Loss
CMGC_MAPK_JNK_MAPK8_ST	P35222	CTNNB1	P45983	MAPK8	S33	D32E	32	Missense	proximal	-1	no	2.673	2.691	EPSD;PhosphoSitePlus	COSMIC	2.638	Up-regulation
CMGC_MAPK_JNK_MAPK8_ST	P35222	CTNNB1	P45983	MAPK8	S33	H36R	36	Missense	distal	3	no	2.673	2.692	EPSD;PhosphoSitePlus	COSMIC	2.638	Up-regulation
CMGC_MAPK_JNK_MAPK8_ST	P35222	CTNNB1	P45983	MAPK8	S33	T40A	40	Missense	distal	7	no	2.673	2.671	EPSD;PhosphoSitePlus	COSMIC	2.638	Down-regulation
CMGC_MAPK_JNK_MAPK8_ST	P35222	CTNNB1	P45983	MAPK8	S33	G34L	34	Missense	proximal	1	no	2.673	2.038	EPSD;PhosphoSitePlus	COSMIC	2.638	Loss
CMGC_MAPK_JNK_MAPK8_ST	P35222	CTNNB1	P45983	MAPK8	S33	S33L	33	Missense	central	0	yes	2.673	0.000	EPSD;PhosphoSitePlus	COSMIC;CCLE	2.638	Loss
CMGC_MAPK_JNK_MAPK8_ST	P35222	CTNNB1	P45983	MAPK8	S33	S29P	29	Missense	distal	-4	no	2.673	2.008	EPSD;PhosphoSitePlus	COSMIC	2.638	Loss
CMGC_MAPK_JNK_MAPK8_ST	P35222	CTNNB1	P45983	MAPK8	S33	L31P	31	Missense	proximal	-2	no	2.673	2.866	EPSD;PhosphoSitePlus	COSMIC	2.638	Up-regulation
CMGC_MAPK_JNK_MAPK8_ST	P35222	CTNNB1	P45983	MAPK8	S33	S37L	37	Missense	distal	4	no	2.673	2.241	EPSD;PhosphoSitePlus	COSMIC	2.638	Loss
CMGC_MAPK_JNK_MAPK8_ST	P35222	CTNNB1	P45983	MAPK8	S33	Q27H	27	Missense	distal	-6	no	2.673	2.753	EPSD;PhosphoSitePlus	COSMIC	2.638	Up-regulation
CMGC_MAPK_JNK_MAPK8_ST	P35222	CTNNB1	P45983	MAPK8	S33	S33N	33	Missense	central	0	yes	2.673	0.000	EPSD;PhosphoSitePlus	COSMIC	2.638	Loss
CMGC_MAPK_JNK_MAPK8_ST	P35222	CTNNB1	P45983	MAPK8	S33	H36Y	36	Missense	distal	3	no	2.673	2.791	EPSD;PhosphoSitePlus	COSMIC	2.638	Up-regulation
CMGC_MAPK_JNK_MAPK8_ST	P35222	CTNNB1	P45983	MAPK8	S33	S29F	29	Missense	distal	-4	no	2.673	1.735	EPSD;PhosphoSitePlus	COSMIC	2.638	Loss
CMGC_MAPK_JNK_MAPK8_ST	P35222	CTNNB1	P45983	MAPK8	S33	Y30C	30	Missense	distal	-3	no	2.673	2.902	EPSD;PhosphoSitePlus	COSMIC	2.638	Up-regulation
CMGC_MAPK_JNK_MAPK8_ST	P35222	CTNNB1	P45983	MAPK8	S33	S29Y	29	Missense	distal	-4	no	2.673	1.440	EPSD;PhosphoSitePlus	COSMIC	2.638	Loss
CMGC_MAPK_JNK_MAPK8_ST	P35222	CTNNB1	P45983	MAPK8	S33	G38P	38	Missense	distal	5	no	2.673	2.688	EPSD;PhosphoSitePlus	COSMIC	2.638	Up-regulation
CMGC_MAPK_JNK_MAPK8_ST	P35222	CTNNB1	P45983	MAPK8	S33	G38D	38	Missense	distal	5	no	2.673	2.652	EPSD;PhosphoSitePlus	COSMIC	2.638	Down-regulation
CMGC_MAPK_JNK_MAPK8_ST	P35222	CTNNB1	P45983	MAPK8	S33	I35M	35	Missense	proximal	2	no	2.673	2.547	EPSD;PhosphoSitePlus	COSMIC	2.638	Loss
CMGC_MAPK_JNK_MAPK8_ST	P35222	CTNNB1	P45983	MAPK8	S33	T40S	40	Missense	distal	7	no	2.673	2.666	EPSD;PhosphoSitePlus	COSMIC	2.638	Down-regulation
CMGC_MAPK_JNK_MAPK8_ST	P35222	CTNNB1	P45983	MAPK8	S33	S29A	29	Missense	distal	-4	no	2.673	2.496	EPSD;PhosphoSitePlus	COSMIC	2.638	Loss
CMGC_MAPK_JNK_MAPK8_ST	P35222	CTNNB1	P45983	MAPK8	S33	G34A	34	Missense	proximal	1	no	2.673	3.263	EPSD;PhosphoSitePlus	COSMIC	2.638	Up-regulation
CMGC_MAPK_JNK_MAPK8_ST	P35222	CTNNB1	P45983	MAPK8	S33	L31W	31	Missense	proximal	-2	no	2.673	2.688	EPSD;PhosphoSitePlus	COSMIC	2.638	Up-regulation
CMGC_MAPK_JNK_MAPK8_ST	P35222	CTNNB1	P45983	MAPK8	S33	G34I	34	Missense	proximal	1	no	2.673	3.737	EPSD;PhosphoSitePlus	COSMIC	2.638	Up-regulation
CMGC_MAPK_JNK_MAPK8_ST	P35222	CTNNB1	P45983	MAPK8	S33	I35N	35	Missense	proximal	2	no	2.673	2.534	EPSD;PhosphoSitePlus	COSMIC	2.638	Loss
CMGC_MAPK_JNK_MAPK8_ST	P35222	CTNNB1	P45983	MAPK8	S33	D32C	32	Missense	proximal	-1	no	2.673	2.668	EPSD;PhosphoSitePlus	COSMIC	2.638	Down-regulation
CMGC_MAPK_JNK_MAPK8_ST	P35222	CTNNB1	P45983	MAPK8	S33	Y30S	30	Missense	distal	-3	no	2.673	3.157	EPSD;PhosphoSitePlus	COSMIC	2.638	Up-regulation
CMGC_MAPK_JNK_MAPK8_ST	P35222	CTNNB1	P45983	MAPK8	S33	L31M	31	Missense	proximal	-2	no	2.673	2.670	EPSD;PhosphoSitePlus	COSMIC	2.638	Down-regulation
CMGC_MAPK_JNK_MAPK8_ST	P35222	CTNNB1	P45983	MAPK8	S33	A39V	39	Missense	distal	6	no	2.673	2.598	EPSD;PhosphoSitePlus	COSMIC	2.638	Loss
CMGC_MAPK_JNK_MAPK8_ST	P35222	CTNNB1	P45983	MAPK8	S33	L31Q	31	Missense	proximal	-2	no	2.673	2.756	EPSD;PhosphoSitePlus	COSMIC	2.638	Up-regulation
CMGC_MAPK_JNK_MAPK8_ST	P35222	CTNNB1	P45983	MAPK8	S33	G34D	34	Missense	proximal	1	no	2.673	3.305	EPSD;PhosphoSitePlus	COSMIC	2.638	Up-regulation
CMGC_MAPK_JNK_MAPK8_ST	P35222	CTNNB1	P45983	MAPK8	S33	Q26R	26	Missense	distal	-7	no	2.673	2.683	EPSD;PhosphoSitePlus	COSMIC;GDSC;CCLE	2.638	Up-regulation
CMGC_MAPK_JNK_MAPK8_ST	P35222	CTNNB1	P45983	MAPK8	S33	S37T	37	Missense	distal	4	no	2.673	2.624	EPSD;PhosphoSitePlus	COSMIC	2.638	Loss
CMGC_MAPK_JNK_MAPK8_ST	P35222	CTNNB1	P45983	MAPK8	S33	I35K	35	Missense	proximal	2	no	2.673	2.877	EPSD;PhosphoSitePlus	COSMIC	2.638	Up-regulation
CMGC_MAPK_JNK_MAPK8_ST	P35222	CTNNB1	P45983	MAPK8	S33	Q28R	28	Missense	distal	-5	no	2.673	2.988	EPSD;PhosphoSitePlus	COSMIC	2.638	Up-regulation
CMGC_MAPK_JNK_MAPK8_ST	P35222	CTNNB1	P45983	MAPK8	S33	D32F	32	Missense	proximal	-1	no	2.673	2.657	EPSD;PhosphoSitePlus	COSMIC	2.638	Down-regulation
CMGC_MAPK_JNK_MAPK8_ST	P35222	CTNNB1	P45983	MAPK8	S33	G38X	38	Missense	distal	5	no	2.673	2.662	EPSD;PhosphoSitePlus	COSMIC	2.638	Down-regulation
CMGC_MAPK_JNK_MAPK8_ST	P35222	CTNNB1	P45983	MAPK8	S33	D32X	32	Missense	proximal	-1	no	2.673	2.669	EPSD;PhosphoSitePlus	COSMIC	2.638	Down-regulation
CMGC_MAPK_JNK_MAPK8_ST	P35222	CTNNB1	P45983	MAPK8	S33	S33K	33	Missense	central	0	yes	2.673	0.000	EPSD;PhosphoSitePlus	COSMIC	2.638	Loss
CMGC_MAPK_JNK_MAPK8_ST	P35222	CTNNB1	P45983	MAPK8	S33	I35V	35	Missense	proximal	2	no	2.673	2.502	EPSD;PhosphoSitePlus	COSMIC	2.638	Loss
CMGC_MAPK_JNK_MAPK8_ST	P35222	CTNNB1	P45983	MAPK8	S33	S29T	29	Missense	distal	-4	no	2.673	2.459	EPSD;PhosphoSitePlus	COSMIC	2.638	Loss
CMGC_MAPK_JNK_MAPK8_ST	P35222	CTNNB1	P45983	MAPK8	S33	G34C	34	Missense	proximal	1	no	2.673	2.032	EPSD;PhosphoSitePlus	COSMIC	2.638	Loss
CMGC_MAPK_JNK_MAPK8_ST	P35222	CTNNB1	P45983	MAPK8	S33	G38S	38	Missense	distal	5	no	2.673	2.605	EPSD;PhosphoSitePlus	COSMIC	2.638	Loss
CMGC_MAPK_JNK_MAPK8_ST	P35222	CTNNB1	P45983	MAPK8	S33	S37V	37	Missense	distal	4	no	2.673	2.154	EPSD;PhosphoSitePlus	COSMIC	2.638	Loss
CMGC_MAPK_JNK_MAPK8_ST	P35222	CTNNB1	P45983	MAPK8	S33	I35F	35	Missense	proximal	2	no	2.673	2.524	EPSD;PhosphoSitePlus	COSMIC	2.638	Loss
CMGC_MAPK_JNK_MAPK8_ST	P35222	CTNNB1	P45983	MAPK8	S33	T40P	40	Missense	distal	7	no	2.673	2.704	EPSD;PhosphoSitePlus	COSMIC	2.638	Up-regulation
CMGC_MAPK_JNK_MAPK8_ST	P35222	CTNNB1	P45983	MAPK8	S37	P44S	44	Missense	distal	7	no	3.848	3.809	PhosphoSitePlus;EPSD	COSMIC	2.638	Down-regulation
CMGC_MAPK_JNK_MAPK8_ST	P35222	CTNNB1	P45983	MAPK8	S37	A43V	43	Missense	distal	6	no	3.848	3.772	PhosphoSitePlus;EPSD	COSMIC	2.638	Down-regulation
CMGC_MAPK_JNK_MAPK8_ST	P35222	CTNNB1	P45983	MAPK8	S37	A39G	39	Missense	proximal	2	no	3.848	3.621	PhosphoSitePlus;EPSD	COSMIC	2.638	Down-regulation
CMGC_MAPK_JNK_MAPK8_ST	P35222	CTNNB1	P45983	MAPK8	S37	G38A	38	Missense	proximal	1	no	3.848	4.438	PhosphoSitePlus;EPSD	COSMIC	2.638	Up-regulation
CMGC_MAPK_JNK_MAPK8_ST	P35222	CTNNB1	P45983	MAPK8	S37	T40I	40	Missense	distal	3	no	3.848	3.944	PhosphoSitePlus;EPSD	COSMIC	2.638	Up-regulation
CMGC_MAPK_JNK_MAPK8_ST	P35222	CTNNB1	P45983	MAPK8	S37	P44A	44	Missense	distal	7	no	3.848	3.815	PhosphoSitePlus;EPSD	COSMIC	2.638	Down-regulation
CMGC_MAPK_JNK_MAPK8_ST	P35222	CTNNB1	P45983	MAPK8	S37	I35T	35	Missense	proximal	-2	no	3.848	3.872	PhosphoSitePlus;EPSD	COSMIC	2.638	Up-regulation
CMGC_MAPK_JNK_MAPK8_ST	P35222	CTNNB1	P45983	MAPK8	S37	T41P	41	Missense	distal	4	no	3.848	3.872	PhosphoSitePlus;EPSD	COSMIC	2.638	Up-regulation
CMGC_MAPK_JNK_MAPK8_ST	P35222	CTNNB1	P45983	MAPK8	S37	T42R	42	Missense	distal	5	no	3.848	3.913	PhosphoSitePlus;EPSD	COSMIC	2.638	Up-regulation
CMGC_MAPK_JNK_MAPK8_ST	P35222	CTNNB1	P45983	MAPK8	S37	D32E	32	Missense	distal	-5	no	3.848	3.605	PhosphoSitePlus;EPSD	COSMIC	2.638	Down-regulation
CMGC_MAPK_JNK_MAPK8_ST	P35222	CTNNB1	P45983	MAPK8	S37	H36R	36	Missense	proximal	-1	no	3.848	3.843	PhosphoSitePlus;EPSD	COSMIC	2.638	Down-regulation
CMGC_MAPK_JNK_MAPK8_ST	P35222	CTNNB1	P45983	MAPK8	S37	T40A	40	Missense	distal	3	no	3.848	3.838	PhosphoSitePlus;EPSD	COSMIC	2.638	Down-regulation
CMGC_MAPK_JNK_MAPK8_ST	P35222	CTNNB1	P45983	MAPK8	S37	P44L	44	Missense	distal	7	no	3.848	3.888	PhosphoSitePlus;EPSD	COSMIC	2.638	Up-regulation
CMGC_MAPK_JNK_MAPK8_ST	P35222	CTNNB1	P45983	MAPK8	S37	G34L	34	Missense	distal	-3	no	3.848	3.788	PhosphoSitePlus;EPSD	COSMIC	2.638	Down-regulation
CMGC_MAPK_JNK_MAPK8_ST	P35222	CTNNB1	P45983	MAPK8	S37	T42I	42	Missense	distal	5	no	3.848	3.889	PhosphoSitePlus;EPSD	COSMIC	2.638	Up-regulation
CMGC_MAPK_JNK_MAPK8_ST	P35222	CTNNB1	P45983	MAPK8	S37	S33L	33	Missense	distal	-4	no	3.848	2.856	PhosphoSitePlus;EPSD	COSMIC;CCLE	2.638	Down-regulation
CMGC_MAPK_JNK_MAPK8_ST	P35222	CTNNB1	P45983	MAPK8	S37	T42S	42	Missense	distal	5	no	3.848	3.841	PhosphoSitePlus;EPSD	COSMIC	2.638	Down-regulation
CMGC_MAPK_JNK_MAPK8_ST	P35222	CTNNB1	P45983	MAPK8	S37	T42K	42	Missense	distal	5	no	3.848	3.822	PhosphoSitePlus;EPSD	COSMIC	2.638	Down-regulation
CMGC_MAPK_JNK_MAPK8_ST	P35222	CTNNB1	P45983	MAPK8	S37	L31P	31	Missense	distal	-6	no	3.848	3.757	PhosphoSitePlus;EPSD	COSMIC	2.638	Down-regulation
CMGC_MAPK_JNK_MAPK8_ST	P35222	CTNNB1	P45983	MAPK8	S37	S37L	37	Missense	central	0	yes	3.848	0.000	PhosphoSitePlus;EPSD	COSMIC	2.638	Loss
CMGC_MAPK_JNK_MAPK8_ST	P35222	CTNNB1	P45983	MAPK8	S37	A39T	39	Missense	proximal	2	no	3.848	3.827	PhosphoSitePlus;EPSD	COSMIC	2.638	Down-regulation
CMGC_MAPK_JNK_MAPK8_ST	P35222	CTNNB1	P45983	MAPK8	S37	S33N	33	Missense	distal	-4	no	3.848	2.974	PhosphoSitePlus;EPSD	COSMIC	2.638	Down-regulation
CMGC_MAPK_JNK_MAPK8_ST	P35222	CTNNB1	P45983	MAPK8	S37	H36Y	36	Missense	proximal	-1	no	3.848	3.830	PhosphoSitePlus;EPSD	COSMIC	2.638	Down-regulation
CMGC_MAPK_JNK_MAPK8_ST	P35222	CTNNB1	P45983	MAPK8	S37	A43P	43	Missense	distal	6	no	3.848	3.827	PhosphoSitePlus;EPSD	COSMIC	2.638	Down-regulation
CMGC_MAPK_JNK_MAPK8_ST	P35222	CTNNB1	P45983	MAPK8	S37	Y30C	30	Missense	distal	-7	no	3.848	3.838	PhosphoSitePlus;EPSD	COSMIC	2.638	Down-regulation
CMGC_MAPK_JNK_MAPK8_ST	P35222	CTNNB1	P45983	MAPK8	S37	G38P	38	Missense	proximal	1	no	3.848	10.785	PhosphoSitePlus;EPSD	COSMIC	2.638	Up-regulation
CMGC_MAPK_JNK_MAPK8_ST	P35222	CTNNB1	P45983	MAPK8	S37	G38D	38	Missense	proximal	1	no	3.848	4.480	PhosphoSitePlus;EPSD	COSMIC	2.638	Up-regulation
CMGC_MAPK_JNK_MAPK8_ST	P35222	CTNNB1	P45983	MAPK8	S37	T42A	42	Missense	distal	5	no	3.848	3.850	PhosphoSitePlus;EPSD	COSMIC	2.638	Up-regulation
CMGC_MAPK_JNK_MAPK8_ST	P35222	CTNNB1	P45983	MAPK8	S37	I35M	35	Missense	proximal	-2	no	3.848	3.755	PhosphoSitePlus;EPSD	COSMIC	2.638	Down-regulation
CMGC_MAPK_JNK_MAPK8_ST	P35222	CTNNB1	P45983	MAPK8	S37	T40S	40	Missense	distal	3	no	3.848	3.820	PhosphoSitePlus;EPSD	COSMIC	2.638	Down-regulation
CMGC_MAPK_JNK_MAPK8_ST	P35222	CTNNB1	P45983	MAPK8	S37	G34A	34	Missense	distal	-3	no	3.848	4.164	PhosphoSitePlus;EPSD	COSMIC	2.638	Up-regulation
CMGC_MAPK_JNK_MAPK8_ST	P35222	CTNNB1	P45983	MAPK8	S37	L31W	31	Missense	distal	-6	no	3.848	3.849	PhosphoSitePlus;EPSD	COSMIC	2.638	Up-regulation
CMGC_MAPK_JNK_MAPK8_ST	P35222	CTNNB1	P45983	MAPK8	S37	T41S	41	Missense	distal	4	no	3.848	3.897	PhosphoSitePlus;EPSD	COSMIC	2.638	Up-regulation
CMGC_MAPK_JNK_MAPK8_ST	P35222	CTNNB1	P45983	MAPK8	S37	G34I	34	Missense	distal	-3	no	3.848	3.969	PhosphoSitePlus;EPSD	COSMIC	2.638	Up-regulation
CMGC_MAPK_JNK_MAPK8_ST	P35222	CTNNB1	P45983	MAPK8	S37	I35N	35	Missense	proximal	-2	no	3.848	3.728	PhosphoSitePlus;EPSD	COSMIC	2.638	Down-regulation
CMGC_MAPK_JNK_MAPK8_ST	P35222	CTNNB1	P45983	MAPK8	S37	T42Q	42	Missense	distal	5	no	3.848	3.861	PhosphoSitePlus;EPSD	COSMIC	2.638	Up-regulation
CMGC_MAPK_JNK_MAPK8_ST	P35222	CTNNB1	P45983	MAPK8	S37	D32C	32	Missense	distal	-5	no	3.848	3.928	PhosphoSitePlus;EPSD	COSMIC	2.638	Up-regulation
CMGC_MAPK_JNK_MAPK8_ST	P35222	CTNNB1	P45983	MAPK8	S37	Y30S	30	Missense	distal	-7	no	3.848	3.827	PhosphoSitePlus;EPSD	COSMIC	2.638	Down-regulation
CMGC_MAPK_JNK_MAPK8_ST	P35222	CTNNB1	P45983	MAPK8	S37	L31M	31	Missense	distal	-6	no	3.848	3.832	PhosphoSitePlus;EPSD	COSMIC	2.638	Down-regulation
CMGC_MAPK_JNK_MAPK8_ST	P35222	CTNNB1	P45983	MAPK8	S37	A39V	39	Missense	proximal	2	no	3.848	3.530	PhosphoSitePlus;EPSD	COSMIC	2.638	Down-regulation
CMGC_MAPK_JNK_MAPK8_ST	P35222	CTNNB1	P45983	MAPK8	S37	L31Q	31	Missense	distal	-6	no	3.848	3.721	PhosphoSitePlus;EPSD	COSMIC	2.638	Down-regulation
CMGC_MAPK_JNK_MAPK8_ST	P35222	CTNNB1	P45983	MAPK8	S37	G34D	34	Missense	distal	-3	no	3.848	3.942	PhosphoSitePlus;EPSD	COSMIC	2.638	Up-regulation
CMGC_MAPK_JNK_MAPK8_ST	P35222	CTNNB1	P45983	MAPK8	S37	I35K	35	Missense	proximal	-2	no	3.848	3.877	PhosphoSitePlus;EPSD	COSMIC	2.638	Up-regulation
CMGC_MAPK_JNK_MAPK8_ST	P35222	CTNNB1	P45983	MAPK8	S37	D32F	32	Missense	distal	-5	no	3.848	4.092	PhosphoSitePlus;EPSD	COSMIC	2.638	Up-regulation
CMGC_MAPK_JNK_MAPK8_ST	P35222	CTNNB1	P45983	MAPK8	S37	G38X	38	Missense	proximal	1	no	3.848	4.078	PhosphoSitePlus;EPSD	COSMIC	2.638	Up-regulation
CMGC_MAPK_JNK_MAPK8_ST	P35222	CTNNB1	P45983	MAPK8	S37	D32X	32	Missense	distal	-5	no	3.848	3.905	PhosphoSitePlus;EPSD	COSMIC	2.638	Up-regulation
CMGC_MAPK_JNK_MAPK8_ST	P35222	CTNNB1	P45983	MAPK8	S37	S33K	33	Missense	distal	-4	no	3.848	3.960	PhosphoSitePlus;EPSD	COSMIC	2.638	Up-regulation
CMGC_MAPK_JNK_MAPK8_ST	P35222	CTNNB1	P45983	MAPK8	S37	I35V	35	Missense	proximal	-2	no	3.848	3.711	PhosphoSitePlus;EPSD	COSMIC	2.638	Down-regulation
CMGC_MAPK_JNK_MAPK8_ST	P35222	CTNNB1	P45983	MAPK8	S37	G34C	34	Missense	distal	-3	no	3.848	3.874	PhosphoSitePlus;EPSD	COSMIC	2.638	Up-regulation
CMGC_MAPK_JNK_MAPK8_ST	P35222	CTNNB1	P45983	MAPK8	S37	G38S	38	Missense	proximal	1	no	3.848	3.057	PhosphoSitePlus;EPSD	COSMIC	2.638	Down-regulation
CMGC_MAPK_JNK_MAPK8_ST	P35222	CTNNB1	P45983	MAPK8	S37	S37V	37	Missense	central	0	yes	3.848	0.000	PhosphoSitePlus;EPSD	COSMIC	2.638	Loss
CMGC_MAPK_JNK_MAPK8_ST	P35222	CTNNB1	P45983	MAPK8	S37	P44I	44	Missense	distal	7	no	3.848	3.849	PhosphoSitePlus;EPSD	COSMIC	2.638	Up-regulation
CMGC_MAPK_JNK_MAPK8_ST	P35222	CTNNB1	P45983	MAPK8	S37	I35F	35	Missense	proximal	-2	no	3.848	3.731	PhosphoSitePlus;EPSD	COSMIC	2.638	Down-regulation
CMGC_MAPK_JNK_MAPK8_ST	P35222	CTNNB1	P45983	MAPK8	S37	T40P	40	Missense	distal	3	no	3.848	3.946	PhosphoSitePlus;EPSD	COSMIC	2.638	Up-regulation
CMGC_MAPK_JNK_MAPK8_ST	P35222	CTNNB1	P45983	MAPK8	T40	T41P	41	Missense	proximal	1	no	0.774	7.761	EPSD	COSMIC	2.638	Gain
CMGC_MAPK_JNK_MAPK8_ST	P35222	CTNNB1	P45983	MAPK8	T41	S45T	45	Missense	distal	4	no	2.715	2.666	EPSD;PhosphoSitePlus	COSMIC	2.638	Down-regulation
CMGC_MAPK_JNK_MAPK8_ST	P35222	CTNNB1	P45983	MAPK8	T41	P44S	44	Missense	distal	3	no	2.715	2.589	EPSD;PhosphoSitePlus	COSMIC	2.638	Loss
CMGC_MAPK_JNK_MAPK8_ST	P35222	CTNNB1	P45983	MAPK8	T41	A43V	43	Missense	proximal	2	no	2.715	2.397	EPSD;PhosphoSitePlus	COSMIC	2.638	Loss
CMGC_MAPK_JNK_MAPK8_ST	P35222	CTNNB1	P45983	MAPK8	T41	G48D	48	Missense	distal	7	no	2.715	2.690	EPSD;PhosphoSitePlus	COSMIC	2.638	Down-regulation
CMGC_MAPK_JNK_MAPK8_ST	P35222	CTNNB1	P45983	MAPK8	T41	A39G	39	Missense	proximal	-2	no	2.715	2.594	EPSD;PhosphoSitePlus	COSMIC	2.638	Loss
CMGC_MAPK_JNK_MAPK8_ST	P35222	CTNNB1	P45983	MAPK8	T41	G38A	38	Missense	distal	-3	no	2.715	3.031	EPSD;PhosphoSitePlus	COSMIC	2.638	Up-regulation
CMGC_MAPK_JNK_MAPK8_ST	P35222	CTNNB1	P45983	MAPK8	T41	T40I	40	Missense	proximal	-1	no	2.715	2.702	EPSD;PhosphoSitePlus	COSMIC	2.638	Down-regulation
CMGC_MAPK_JNK_MAPK8_ST	P35222	CTNNB1	P45983	MAPK8	T41	P44A	44	Missense	distal	3	no	2.715	2.607	EPSD;PhosphoSitePlus	COSMIC	2.638	Loss
CMGC_MAPK_JNK_MAPK8_ST	P35222	CTNNB1	P45983	MAPK8	T41	I35T	35	Missense	distal	-6	no	2.715	2.647	EPSD;PhosphoSitePlus	COSMIC	2.638	Down-regulation
CMGC_MAPK_JNK_MAPK8_ST	P35222	CTNNB1	P45983	MAPK8	T41	T41P	41	Missense	central	0	yes	2.715	0.000	EPSD;PhosphoSitePlus	COSMIC	2.638	Loss
CMGC_MAPK_JNK_MAPK8_ST	P35222	CTNNB1	P45983	MAPK8	T41	T42R	42	Missense	proximal	1	no	2.715	2.565	EPSD;PhosphoSitePlus	COSMIC	2.638	Loss
CMGC_MAPK_JNK_MAPK8_ST	P35222	CTNNB1	P45983	MAPK8	T41	S45A	45	Missense	distal	4	no	2.715	2.714	EPSD;PhosphoSitePlus	COSMIC	2.638	Down-regulation
CMGC_MAPK_JNK_MAPK8_ST	P35222	CTNNB1	P45983	MAPK8	T41	H36R	36	Missense	distal	-5	no	2.715	2.810	EPSD;PhosphoSitePlus	COSMIC	2.638	Up-regulation
CMGC_MAPK_JNK_MAPK8_ST	P35222	CTNNB1	P45983	MAPK8	T41	G48S	48	Missense	distal	7	no	2.715	2.650	EPSD;PhosphoSitePlus	COSMIC	2.638	Down-regulation
CMGC_MAPK_JNK_MAPK8_ST	P35222	CTNNB1	P45983	MAPK8	T41	T40A	40	Missense	proximal	-1	no	2.715	2.716	EPSD;PhosphoSitePlus	COSMIC	2.638	Up-regulation
CMGC_MAPK_JNK_MAPK8_ST	P35222	CTNNB1	P45983	MAPK8	T41	A43T	43	Missense	proximal	2	no	2.715	2.694	EPSD;PhosphoSitePlus	COSMIC	2.638	Down-regulation
CMGC_MAPK_JNK_MAPK8_ST	P35222	CTNNB1	P45983	MAPK8	T41	P44L	44	Missense	distal	3	no	2.715	2.816	EPSD;PhosphoSitePlus	COSMIC	2.638	Up-regulation
CMGC_MAPK_JNK_MAPK8_ST	P35222	CTNNB1	P45983	MAPK8	T41	G34L	34	Missense	distal	-7	no	2.715	2.719	EPSD;PhosphoSitePlus	COSMIC	2.638	Up-regulation
CMGC_MAPK_JNK_MAPK8_ST	P35222	CTNNB1	P45983	MAPK8	T41	T42I	42	Missense	proximal	1	no	2.715	3.828	EPSD;PhosphoSitePlus	COSMIC	2.638	Up-regulation
CMGC_MAPK_JNK_MAPK8_ST	P35222	CTNNB1	P45983	MAPK8	T41	T42S	42	Missense	proximal	1	no	2.715	1.973	EPSD;PhosphoSitePlus	COSMIC	2.638	Loss
CMGC_MAPK_JNK_MAPK8_ST	P35222	CTNNB1	P45983	MAPK8	T41	T42K	42	Missense	proximal	1	no	2.715	1.854	EPSD;PhosphoSitePlus	COSMIC	2.638	Loss
CMGC_MAPK_JNK_MAPK8_ST	P35222	CTNNB1	P45983	MAPK8	T41	S47G	47	Missense	distal	6	no	2.715	2.658	EPSD;PhosphoSitePlus	COSMIC	2.638	Down-regulation
CMGC_MAPK_JNK_MAPK8_ST	P35222	CTNNB1	P45983	MAPK8	T41	G48V	48	Missense	distal	7	no	2.715	2.735	EPSD;PhosphoSitePlus	COSMIC	2.638	Up-regulation
CMGC_MAPK_JNK_MAPK8_ST	P35222	CTNNB1	P45983	MAPK8	T41	S47N	47	Missense	distal	6	no	2.715	2.650	EPSD;PhosphoSitePlus	COSMIC	2.638	Down-regulation
CMGC_MAPK_JNK_MAPK8_ST	P35222	CTNNB1	P45983	MAPK8	T41	S37L	37	Missense	distal	-4	no	2.715	1.723	EPSD;PhosphoSitePlus	COSMIC	2.638	Loss
CMGC_MAPK_JNK_MAPK8_ST	P35222	CTNNB1	P45983	MAPK8	T41	A39T	39	Missense	proximal	-2	no	2.715	2.685	EPSD;PhosphoSitePlus	COSMIC	2.638	Down-regulation
CMGC_MAPK_JNK_MAPK8_ST	P35222	CTNNB1	P45983	MAPK8	T41	H36Y	36	Missense	distal	-5	no	2.715	3.006	EPSD;PhosphoSitePlus	COSMIC	2.638	Up-regulation
CMGC_MAPK_JNK_MAPK8_ST	P35222	CTNNB1	P45983	MAPK8	T41	A43P	43	Missense	proximal	2	no	2.715	2.505	EPSD;PhosphoSitePlus	COSMIC	2.638	Loss
CMGC_MAPK_JNK_MAPK8_ST	P35222	CTNNB1	P45983	MAPK8	T41	L46P	46	Missense	distal	5	no	2.715	2.716	EPSD;PhosphoSitePlus	COSMIC	2.638	Up-regulation
CMGC_MAPK_JNK_MAPK8_ST	P35222	CTNNB1	P45983	MAPK8	T41	G38P	38	Missense	distal	-3	no	2.715	2.834	EPSD;PhosphoSitePlus	COSMIC	2.638	Up-regulation
CMGC_MAPK_JNK_MAPK8_ST	P35222	CTNNB1	P45983	MAPK8	T41	G38D	38	Missense	distal	-3	no	2.715	2.809	EPSD;PhosphoSitePlus	COSMIC	2.638	Up-regulation
CMGC_MAPK_JNK_MAPK8_ST	P35222	CTNNB1	P45983	MAPK8	T41	T42A	42	Missense	proximal	1	no	2.715	3.354	EPSD;PhosphoSitePlus	COSMIC	2.638	Up-regulation
CMGC_MAPK_JNK_MAPK8_ST	P35222	CTNNB1	P45983	MAPK8	T41	S47L	47	Missense	distal	6	no	2.715	2.644	EPSD;PhosphoSitePlus	COSMIC	2.638	Down-regulation
CMGC_MAPK_JNK_MAPK8_ST	P35222	CTNNB1	P45983	MAPK8	T41	I35M	35	Missense	distal	-6	no	2.715	2.786	EPSD;PhosphoSitePlus	COSMIC	2.638	Up-regulation
CMGC_MAPK_JNK_MAPK8_ST	P35222	CTNNB1	P45983	MAPK8	T41	T40S	40	Missense	proximal	-1	no	2.715	2.714	EPSD;PhosphoSitePlus	COSMIC	2.638	Down-regulation
CMGC_MAPK_JNK_MAPK8_ST	P35222	CTNNB1	P45983	MAPK8	T41	L46M	46	Missense	distal	5	no	2.715	2.706	EPSD;PhosphoSitePlus	COSMIC	2.638	Down-regulation
CMGC_MAPK_JNK_MAPK8_ST	P35222	CTNNB1	P45983	MAPK8	T41	G34A	34	Missense	distal	-7	no	2.715	2.702	EPSD;PhosphoSitePlus	COSMIC	2.638	Down-regulation
CMGC_MAPK_JNK_MAPK8_ST	P35222	CTNNB1	P45983	MAPK8	T41	S47T	47	Missense	distal	6	no	2.715	2.712	EPSD;PhosphoSitePlus	COSMIC	2.638	Down-regulation
CMGC_MAPK_JNK_MAPK8_ST	P35222	CTNNB1	P45983	MAPK8	T41	G34I	34	Missense	distal	-7	no	2.715	2.710	EPSD;PhosphoSitePlus	COSMIC	2.638	Down-regulation
CMGC_MAPK_JNK_MAPK8_ST	P35222	CTNNB1	P45983	MAPK8	T41	I35N	35	Missense	distal	-6	no	2.715	2.797	EPSD;PhosphoSitePlus	COSMIC	2.638	Up-regulation
CMGC_MAPK_JNK_MAPK8_ST	P35222	CTNNB1	P45983	MAPK8	T41	T42Q	42	Missense	proximal	1	no	2.715	2.592	EPSD;PhosphoSitePlus	COSMIC	2.638	Loss
CMGC_MAPK_JNK_MAPK8_ST	P35222	CTNNB1	P45983	MAPK8	T41	S47C	47	Missense	distal	6	no	2.715	2.666	EPSD;PhosphoSitePlus	COSMIC	2.638	Down-regulation
CMGC_MAPK_JNK_MAPK8_ST	P35222	CTNNB1	P45983	MAPK8	T41	S47R	47	Missense	distal	6	no	2.715	2.655	EPSD;PhosphoSitePlus	COSMIC	2.638	Down-regulation
CMGC_MAPK_JNK_MAPK8_ST	P35222	CTNNB1	P45983	MAPK8	T41	A39V	39	Missense	proximal	-2	no	2.715	2.524	EPSD;PhosphoSitePlus	COSMIC	2.638	Loss
CMGC_MAPK_JNK_MAPK8_ST	P35222	CTNNB1	P45983	MAPK8	T41	S45E	45	Missense	distal	4	no	2.715	2.664	EPSD;PhosphoSitePlus	COSMIC	2.638	Down-regulation
CMGC_MAPK_JNK_MAPK8_ST	P35222	CTNNB1	P45983	MAPK8	T41	G34D	34	Missense	distal	-7	no	2.715	2.710	EPSD;PhosphoSitePlus	COSMIC	2.638	Down-regulation
CMGC_MAPK_JNK_MAPK8_ST	P35222	CTNNB1	P45983	MAPK8	T41	S37T	37	Missense	distal	-4	no	2.715	2.500	EPSD;PhosphoSitePlus	COSMIC	2.638	Loss
CMGC_MAPK_JNK_MAPK8_ST	P35222	CTNNB1	P45983	MAPK8	T41	I35K	35	Missense	distal	-6	no	2.715	2.610	EPSD;PhosphoSitePlus	COSMIC	2.638	Loss
CMGC_MAPK_JNK_MAPK8_ST	P35222	CTNNB1	P45983	MAPK8	T41	S45N	45	Missense	distal	4	no	2.715	2.267	EPSD;PhosphoSitePlus	COSMIC	2.638	Loss
CMGC_MAPK_JNK_MAPK8_ST	P35222	CTNNB1	P45983	MAPK8	T41	G38X	38	Missense	distal	-3	no	2.715	2.744	EPSD;PhosphoSitePlus	COSMIC	2.638	Up-regulation
CMGC_MAPK_JNK_MAPK8_ST	P35222	CTNNB1	P45983	MAPK8	T41	L46Q	46	Missense	distal	5	no	2.715	2.654	EPSD;PhosphoSitePlus	COSMIC	2.638	Down-regulation
CMGC_MAPK_JNK_MAPK8_ST	P35222	CTNNB1	P45983	MAPK8	T41	I35V	35	Missense	distal	-6	no	2.715	2.826	EPSD;PhosphoSitePlus	COSMIC	2.638	Up-regulation
CMGC_MAPK_JNK_MAPK8_ST	P35222	CTNNB1	P45983	MAPK8	T41	S45X	45	Missense	distal	4	no	2.715	2.423	EPSD;PhosphoSitePlus	COSMIC	2.638	Loss
CMGC_MAPK_JNK_MAPK8_ST	P35222	CTNNB1	P45983	MAPK8	T41	G34C	34	Missense	distal	-7	no	2.715	2.713	EPSD;PhosphoSitePlus	COSMIC	2.638	Down-regulation
CMGC_MAPK_JNK_MAPK8_ST	P35222	CTNNB1	P45983	MAPK8	T41	G38S	38	Missense	distal	-3	no	2.715	2.996	EPSD;PhosphoSitePlus	COSMIC	2.638	Up-regulation
CMGC_MAPK_JNK_MAPK8_ST	P35222	CTNNB1	P45983	MAPK8	T41	S37V	37	Missense	distal	-4	no	2.715	1.682	EPSD;PhosphoSitePlus	COSMIC	2.638	Loss
CMGC_MAPK_JNK_MAPK8_ST	P35222	CTNNB1	P45983	MAPK8	T41	P44I	44	Missense	distal	3	no	2.715	2.713	EPSD;PhosphoSitePlus	COSMIC	2.638	Down-regulation
CMGC_MAPK_JNK_MAPK8_ST	P35222	CTNNB1	P45983	MAPK8	T41	I35F	35	Missense	distal	-6	no	2.715	2.802	EPSD;PhosphoSitePlus	COSMIC	2.638	Up-regulation
CMGC_MAPK_JNK_MAPK8_ST	P35222	CTNNB1	P45983	MAPK8	T41	S47I	47	Missense	distal	6	no	2.715	2.681	EPSD;PhosphoSitePlus	COSMIC	2.638	Down-regulation
CMGC_MAPK_JNK_MAPK8_ST	P35222	CTNNB1	P45983	MAPK8	T41	S47Y	47	Missense	distal	6	no	2.715	2.629	EPSD;PhosphoSitePlus	COSMIC	2.638	Loss
CMGC_MAPK_JNK_MAPK8_ST	P35222	CTNNB1	P45983	MAPK8	T41	T40P	40	Missense	proximal	-1	no	2.715	2.704	EPSD;PhosphoSitePlus	COSMIC	2.638	Down-regulation
CMGC_MAPK_JNK_MAPK8_ST	P35222	CTNNB1	P45983	MAPK8	T42	A43P	43	Missense	proximal	1	no	-0.775	5.572	EPSD	COSMIC	2.638	Gain
CMGC_MAPK_JNK_MAPK8_ST	P35222	CTNNB1	P45983	MAPK8	S45	A39G	39	Missense	distal	-6	no	2.544	2.692	EPSD	COSMIC	2.638	Gain
CMGC_MAPK_JNK_MAPK8_ST	P35222	CTNNB1	P45983	MAPK8	S45	T40I	40	Missense	distal	-5	no	2.544	2.748	EPSD	COSMIC	2.638	Gain
CMGC_MAPK_JNK_MAPK8_ST	P35222	CTNNB1	P45983	MAPK8	S45	T42K	42	Missense	distal	-3	no	2.544	2.641	EPSD	COSMIC	2.638	Gain
CMGC_MAPK_JNK_MAPK8_ST	P35222	CTNNB1	P45983	MAPK8	S45	L46P	46	Missense	proximal	1	no	2.544	10.117	EPSD	COSMIC	2.638	Gain
CMGC_MAPK_JNK_MAPK8_ST	P35222	CTNNB1	P45983	MAPK8	S45	T41S	41	Missense	distal	-4	no	2.544	2.759	EPSD	COSMIC	2.638	Gain
CMGC_MAPK_JNK_MAPK8_ST	P35222	CTNNB1	P45983	MAPK8	S45	A39V	39	Missense	distal	-6	no	2.544	2.746	EPSD	COSMIC	2.638	Gain
CMGC_MAPK_JNK_MAPK8_ST	P35222	CTNNB1	P45983	MAPK8	S45	L46Q	46	Missense	proximal	1	no	2.544	3.008	EPSD	COSMIC	2.638	Gain
CMGC_MAPK_JNK_MAPK8_ST	P35222	CTNNB1	P45983	MAPK8	S45	T40P	40	Missense	distal	-5	no	2.544	2.656	EPSD	COSMIC	2.638	Gain
CMGC_MAPK_JNK_MAPK8_ST	P35222	CTNNB1	P45983	MAPK8	S47	S45T	45	Missense	proximal	-2	no	2.699	2.724	EPSD	COSMIC	2.638	Up-regulation
CMGC_MAPK_JNK_MAPK8_ST	P35222	CTNNB1	P45983	MAPK8	S47	P44S	44	Missense	distal	-3	no	2.699	2.861	EPSD	COSMIC	2.638	Up-regulation
CMGC_MAPK_JNK_MAPK8_ST	P35222	CTNNB1	P45983	MAPK8	S47	A43V	43	Missense	distal	-4	no	2.699	1.843	EPSD	COSMIC	2.638	Loss
CMGC_MAPK_JNK_MAPK8_ST	P35222	CTNNB1	P45983	MAPK8	S47	G48D	48	Missense	proximal	1	no	2.699	3.331	EPSD	COSMIC	2.638	Up-regulation
CMGC_MAPK_JNK_MAPK8_ST	P35222	CTNNB1	P45983	MAPK8	S47	N51T	51	Missense	distal	4	no	2.699	3.098	EPSD	COSMIC	2.638	Up-regulation
CMGC_MAPK_JNK_MAPK8_ST	P35222	CTNNB1	P45983	MAPK8	S47	P52L	52	Missense	distal	5	no	2.699	2.697	EPSD	COSMIC	2.638	Down-regulation
CMGC_MAPK_JNK_MAPK8_ST	P35222	CTNNB1	P45983	MAPK8	S47	E53K	53	Missense	distal	6	no	2.699	2.715	EPSD	COSMIC	2.638	Up-regulation
CMGC_MAPK_JNK_MAPK8_ST	P35222	CTNNB1	P45983	MAPK8	S47	N51S	51	Missense	distal	4	no	2.699	3.147	EPSD	COSMIC	2.638	Up-regulation
CMGC_MAPK_JNK_MAPK8_ST	P35222	CTNNB1	P45983	MAPK8	S47	T40I	40	Missense	distal	-7	no	2.699	2.706	EPSD	COSMIC	2.638	Up-regulation
CMGC_MAPK_JNK_MAPK8_ST	P35222	CTNNB1	P45983	MAPK8	S47	P44A	44	Missense	distal	-3	no	2.699	2.896	EPSD	COSMIC	2.638	Up-regulation
CMGC_MAPK_JNK_MAPK8_ST	P35222	CTNNB1	P45983	MAPK8	S47	T41P	41	Missense	distal	-6	no	2.699	2.762	EPSD	COSMIC	2.638	Up-regulation
CMGC_MAPK_JNK_MAPK8_ST	P35222	CTNNB1	P45983	MAPK8	S47	E54K	54	Missense	distal	7	no	2.699	2.684	EPSD	COSMIC	2.638	Down-regulation
CMGC_MAPK_JNK_MAPK8_ST	P35222	CTNNB1	P45983	MAPK8	S47	K49R	49	Missense	proximal	2	no	2.699	2.376	EPSD	COSMIC	2.638	Loss
CMGC_MAPK_JNK_MAPK8_ST	P35222	CTNNB1	P45983	MAPK8	S47	T42R	42	Missense	distal	-5	no	2.699	3.103	EPSD	COSMIC	2.638	Up-regulation
CMGC_MAPK_JNK_MAPK8_ST	P35222	CTNNB1	P45983	MAPK8	S47	S45A	45	Missense	proximal	-2	no	2.699	2.754	EPSD	COSMIC	2.638	Up-regulation
CMGC_MAPK_JNK_MAPK8_ST	P35222	CTNNB1	P45983	MAPK8	S47	G48S	48	Missense	proximal	1	no	2.699	1.907	EPSD	COSMIC	2.638	Loss
CMGC_MAPK_JNK_MAPK8_ST	P35222	CTNNB1	P45983	MAPK8	S47	T40A	40	Missense	distal	-7	no	2.699	2.697	EPSD	COSMIC	2.638	Down-regulation
CMGC_MAPK_JNK_MAPK8_ST	P35222	CTNNB1	P45983	MAPK8	S47	A43T	43	Missense	distal	-4	no	2.699	2.662	EPSD	COSMIC	2.638	Down-regulation
CMGC_MAPK_JNK_MAPK8_ST	P35222	CTNNB1	P45983	MAPK8	S47	P44L	44	Missense	distal	-3	no	2.699	2.520	EPSD	COSMIC	2.638	Loss
CMGC_MAPK_JNK_MAPK8_ST	P35222	CTNNB1	P45983	MAPK8	S47	E54G	54	Missense	distal	7	no	2.699	2.763	EPSD	COSMIC	2.638	Up-regulation
CMGC_MAPK_JNK_MAPK8_ST	P35222	CTNNB1	P45983	MAPK8	S47	T42I	42	Missense	distal	-5	no	2.699	2.903	EPSD	COSMIC	2.638	Up-regulation
CMGC_MAPK_JNK_MAPK8_ST	P35222	CTNNB1	P45983	MAPK8	S47	T42K	42	Missense	distal	-5	no	2.699	2.604	EPSD	COSMIC	2.638	Loss
CMGC_MAPK_JNK_MAPK8_ST	P35222	CTNNB1	P45983	MAPK8	S47	S47G	47	Missense	central	0	yes	2.699	0.000	EPSD	COSMIC	2.638	Loss
CMGC_MAPK_JNK_MAPK8_ST	P35222	CTNNB1	P45983	MAPK8	S47	G48V	48	Missense	proximal	1	no	2.699	0.892	EPSD	COSMIC	2.638	Loss
CMGC_MAPK_JNK_MAPK8_ST	P35222	CTNNB1	P45983	MAPK8	S47	S47N	47	Missense	central	0	yes	2.699	0.000	EPSD	COSMIC	2.638	Loss
CMGC_MAPK_JNK_MAPK8_ST	P35222	CTNNB1	P45983	MAPK8	S47	K49T	49	Missense	proximal	2	no	2.699	2.620	EPSD	COSMIC	2.638	Loss
CMGC_MAPK_JNK_MAPK8_ST	P35222	CTNNB1	P45983	MAPK8	S47	G50D	50	Missense	distal	3	no	2.699	2.629	EPSD	COSMIC	2.638	Loss
CMGC_MAPK_JNK_MAPK8_ST	P35222	CTNNB1	P45983	MAPK8	S47	A43P	43	Missense	distal	-4	no	2.699	2.211	EPSD	COSMIC	2.638	Loss
CMGC_MAPK_JNK_MAPK8_ST	P35222	CTNNB1	P45983	MAPK8	S47	L46P	46	Missense	proximal	-1	no	2.699	2.717	EPSD	COSMIC	2.638	Up-regulation
CMGC_MAPK_JNK_MAPK8_ST	P35222	CTNNB1	P45983	MAPK8	S47	T42A	42	Missense	distal	-5	no	2.699	2.682	EPSD	COSMIC	2.638	Down-regulation
CMGC_MAPK_JNK_MAPK8_ST	P35222	CTNNB1	P45983	MAPK8	S47	L46V	46	Missense	proximal	-1	no	2.699	2.693	EPSD	COSMIC	2.638	Down-regulation
CMGC_MAPK_JNK_MAPK8_ST	P35222	CTNNB1	P45983	MAPK8	S47	S47L	47	Missense	central	0	yes	2.699	0.000	EPSD	COSMIC	2.638	Loss
CMGC_MAPK_JNK_MAPK8_ST	P35222	CTNNB1	P45983	MAPK8	S47	T40S	40	Missense	distal	-7	no	2.699	2.697	EPSD	COSMIC	2.638	Down-regulation
CMGC_MAPK_JNK_MAPK8_ST	P35222	CTNNB1	P45983	MAPK8	S47	K49L	49	Missense	proximal	2	no	2.699	2.355	EPSD	COSMIC	2.638	Loss
CMGC_MAPK_JNK_MAPK8_ST	P35222	CTNNB1	P45983	MAPK8	S47	L46M	46	Missense	proximal	-1	no	2.699	2.701	EPSD	COSMIC	2.638	Up-regulation
CMGC_MAPK_JNK_MAPK8_ST	P35222	CTNNB1	P45983	MAPK8	S47	T41S	41	Missense	distal	-6	no	2.699	2.673	EPSD	COSMIC	2.638	Down-regulation
CMGC_MAPK_JNK_MAPK8_ST	P35222	CTNNB1	P45983	MAPK8	S47	T42Q	42	Missense	distal	-5	no	2.699	2.788	EPSD	COSMIC	2.638	Up-regulation
CMGC_MAPK_JNK_MAPK8_ST	P35222	CTNNB1	P45983	MAPK8	S47	S47C	47	Missense	central	0	yes	2.699	0.000	EPSD	COSMIC	2.638	Loss
CMGC_MAPK_JNK_MAPK8_ST	P35222	CTNNB1	P45983	MAPK8	S47	K49E	49	Missense	proximal	2	no	2.699	2.681	EPSD	COSMIC	2.638	Down-regulation
CMGC_MAPK_JNK_MAPK8_ST	P35222	CTNNB1	P45983	MAPK8	S47	S47R	47	Missense	central	0	yes	2.699	0.000	EPSD	COSMIC	2.638	Loss
CMGC_MAPK_JNK_MAPK8_ST	P35222	CTNNB1	P45983	MAPK8	S47	S45E	45	Missense	proximal	-2	no	2.699	2.732	EPSD	COSMIC	2.638	Up-regulation
CMGC_MAPK_JNK_MAPK8_ST	P35222	CTNNB1	P45983	MAPK8	S47	G50S	50	Missense	distal	3	no	2.699	2.509	EPSD	COSMIC	2.638	Loss
CMGC_MAPK_JNK_MAPK8_ST	P35222	CTNNB1	P45983	MAPK8	S47	S45N	45	Missense	proximal	-2	no	2.699	2.581	EPSD	COSMIC	2.638	Loss
CMGC_MAPK_JNK_MAPK8_ST	P35222	CTNNB1	P45983	MAPK8	S47	L46Q	46	Missense	proximal	-1	no	2.699	2.722	EPSD	COSMIC	2.638	Up-regulation
CMGC_MAPK_JNK_MAPK8_ST	P35222	CTNNB1	P45983	MAPK8	S47	S45X	45	Missense	proximal	-2	no	2.699	2.653	EPSD	COSMIC	2.638	Down-regulation
CMGC_MAPK_JNK_MAPK8_ST	P35222	CTNNB1	P45983	MAPK8	S47	P44I	44	Missense	distal	-3	no	2.699	2.701	EPSD	COSMIC	2.638	Up-regulation
CMGC_MAPK_JNK_MAPK8_ST	P35222	CTNNB1	P45983	MAPK8	S47	S47I	47	Missense	central	0	yes	2.699	0.000	EPSD	COSMIC	2.638	Loss
CMGC_MAPK_JNK_MAPK8_ST	P35222	CTNNB1	P45983	MAPK8	S47	S47Y	47	Missense	central	0	yes	2.699	0.000	EPSD	COSMIC	2.638	Loss
CMGC_MAPK_JNK_MAPK8_ST	P35222	CTNNB1	P45983	MAPK8	S47	T40P	40	Missense	distal	-7	no	2.699	2.703	EPSD	COSMIC	2.638	Up-regulation
CMGC_MAPK_JNK_MAPK8_ST	P35222	CTNNB1	P45983	MAPK8	S71	E67K	67	Missense	distal	-4	no	2.435	2.691	EPSD	COSMIC	2.638	Gain
CMGC_MAPK_JNK_MAPK8_ST	P35222	CTNNB1	P45983	MAPK8	S191	P192S	192	Missense	proximal	1	no	8.259	0.530	EPSD	COSMIC	2.638	Loss
CMGC_MAPK_JNK_MAPK8_ST	P35222	CTNNB1	P45983	MAPK8	S191	A187T	187	Missense	distal	-4	no	8.259	8.222	EPSD	COSMIC	2.638	Down-regulation
CMGC_MAPK_JNK_MAPK8_ST	P35222	CTNNB1	P45983	MAPK8	S191	R190C	190	Missense	proximal	-1	no	8.259	8.265	EPSD	COSMIC	2.638	Up-regulation
CMGC_MAPK_JNK_MAPK8_ST	P35222	CTNNB1	P45983	MAPK8	S191	A187D	187	Missense	distal	-4	no	8.259	7.870	EPSD	COSMIC	2.638	Down-regulation
CMGC_MAPK_JNK_MAPK8_ST	P35222	CTNNB1	P45983	MAPK8	S191	P192H	192	Missense	proximal	1	no	8.259	0.344	EPSD	COSMIC	2.638	Loss
CMGC_MAPK_JNK_MAPK8_ST	P35222	CTNNB1	P45983	MAPK8	S191	I188M	188	Missense	distal	-3	no	8.259	8.093	EPSD	COSMIC	2.638	Down-regulation
CMGC_MAPK_JNK_MAPK8_ST	P35222	CTNNB1	P45983	MAPK8	S191	R190H	190	Missense	proximal	-1	no	8.259	8.264	EPSD	COSMIC	2.638	Up-regulation
CMGC_MAPK_JNK_MAPK8_ST	P35222	CTNNB1	P45983	MAPK8	S191	I198L	198	Missense	distal	7	no	8.259	8.297	EPSD	COSMIC	2.638	Up-regulation
CMGC_MAPK_JNK_MAPK8_ST	P35222	CTNNB1	P45983	MAPK8	S191	A187V	187	Missense	distal	-4	no	8.259	7.403	EPSD	COSMIC	2.638	Down-regulation
CMGC_MAPK_JNK_MAPK8_ST	P35222	CTNNB1	P45983	MAPK8	S191	R185K	185	Missense	distal	-6	no	8.259	8.092	EPSD	COSMIC	2.638	Down-regulation
CMGC_MAPK_JNK_MAPK8_ST	P35222	CTNNB1	P45983	MAPK8	S196	P192S	192	Missense	distal	-4	no	1.986	2.651	EPSD	COSMIC	2.638	Gain
CMGC_MAPK_JNK_MAPK8_ST	P35222	CTNNB1	P45983	MAPK8	S246	M243T	243	Missense	distal	-3	no	7.678	7.985	EPSD	COSMIC	2.638	Up-regulation
CMGC_MAPK_JNK_MAPK8_ST	P35222	CTNNB1	P45983	MAPK8	S246	S246L	246	Missense	central	0	yes	7.678	0.000	EPSD	COSMIC	2.638	Loss
CMGC_MAPK_JNK_MAPK8_ST	P35222	CTNNB1	P45983	MAPK8	S246	G245A	245	Missense	proximal	-1	no	7.678	7.704	EPSD	COSMIC;GDSC	2.638	Up-regulation
CMGC_MAPK_JNK_MAPK8_ST	P35222	CTNNB1	P45983	MAPK8	S246	G245D	245	Missense	proximal	-1	no	7.678	7.689	EPSD	COSMIC	2.638	Up-regulation
CMGC_MAPK_JNK_MAPK8_ST	P35222	CTNNB1	P45983	MAPK8	S246	A239V	239	Missense	distal	-7	no	7.678	7.696	EPSD	COSMIC	2.638	Up-regulation
CMGC_MAPK_JNK_MAPK8_ST	P35222	CTNNB1	P45983	MAPK8	S246	K242E	242	Missense	distal	-4	no	7.678	7.422	EPSD	COSMIC	2.638	Down-regulation
CMGC_MAPK_JNK_MAPK8_ST	P35222	CTNNB1	P45983	MAPK8	S246	A239G	239	Missense	distal	-7	no	7.678	7.691	EPSD	COSMIC	2.638	Up-regulation
CMGC_MAPK_JNK_MAPK8_ST	P35222	CTNNB1	P45983	MAPK8	S605	V600G	600	Missense	distal	-5	no	6.304	6.155	EPSD	COSMIC	2.638	Down-regulation
CMGC_MAPK_JNK_MAPK8_ST	P35222	CTNNB1	P45983	MAPK8	S605	R612T	612	Missense	distal	7	no	6.304	6.248	EPSD	COSMIC	2.638	Down-regulation
CMGC_MAPK_JNK_MAPK8_ST	P35222	CTNNB1	P45983	MAPK8	S605	V600L	600	Missense	distal	-5	no	6.304	6.251	EPSD	COSMIC;GDSC;CCLE	2.638	Down-regulation
CMGC_MAPK_JNK_MAPK8_ST	P35222	CTNNB1	P45983	MAPK8	S605	V600A	600	Missense	distal	-5	no	6.304	5.762	EPSD	COSMIC	2.638	Down-regulation
CMGC_MAPK_JNK_MAPK8_ST	P35222	CTNNB1	P45983	MAPK8	S605	F599L	599	Missense	distal	-6	no	6.304	6.303	EPSD	COSMIC	2.638	Down-regulation
CMGC_MAPK_JNK_MAPK8_ST	P35222	CTNNB1	P45983	MAPK8	S605	Q611R	611	Missense	distal	6	no	6.304	6.258	EPSD	COSMIC	2.638	Down-regulation
CMGC_MAPK_JNK_MAPK8_ST	P35222	CTNNB1	P45983	MAPK8	S605	L603R	603	Missense	proximal	-2	no	6.304	6.313	EPSD	COSMIC	2.638	Up-regulation
CMGC_MAPK_JNK_MAPK8_ST	P35222	CTNNB1	P45983	MAPK8	S605	L603Q	603	Missense	proximal	-2	no	6.304	6.387	EPSD	COSMIC	2.638	Up-regulation
CMGC_MAPK_JNK_MAPK8_ST	Q99607	ELF4	P45983	MAPK8	S641	S634C	634	Missense	distal	-7	no	8.197	8.209	PhosphoSitePlus	COSMIC;CCLE	2.638	Up-regulation
CMGC_MAPK_JNK_MAPK8_ST	Q99607	ELF4	P45983	MAPK8	T643	P649Q	649	Missense	distal	6	no	6.925	6.935	EPSD	COSMIC	2.638	Up-regulation
CMGC_MAPK_JNK_MAPK8_ST	Q99607	ELF4	P45983	MAPK8	S648	P649Q	649	Missense	proximal	1	no	7.748	0.638	EPSD	COSMIC	2.638	Loss
CMGC_MAPK_JNK_MAPK8_ST	P05412	JUN	P45983	MAPK8	S63	K56N	56	Missense	distal	-7	no	7.247	7.265	EPSD;PhosphoSitePlus	COSMIC	2.638	Up-regulation
CMGC_MAPK_JNK_MAPK8_ST	P05412	JUN	P45983	MAPK8	S63	L61F	61	Missense	proximal	-2	no	7.247	7.219	EPSD;PhosphoSitePlus	COSMIC	2.638	Down-regulation
CMGC_MAPK_JNK_MAPK8_ST	P05412	JUN	P45983	MAPK8	S73	R78H	78	Missense	distal	5	no	8.495	8.474	PhosphoSitePlus;EPSD	COSMIC	2.638	Down-regulation
CMGC_MAPK_JNK_MAPK8_ST	P05412	JUN	P45983	MAPK8	T91	P92Q	92	Missense	proximal	1	no	8.328	1.219	EPSD;PhosphoSitePlus	COSMIC	2.638	Loss
CMGC_MAPK_JNK_MAPK8_ST	P05412	JUN	P45983	MAPK8	T91	L98M	98	Missense	distal	7	no	8.328	8.317	EPSD;PhosphoSitePlus	COSMIC	2.638	Down-regulation
CMGC_MAPK_JNK_MAPK8_ST	P05412	JUN	P45983	MAPK8	T91	P94S	94	Missense	distal	3	no	8.328	8.203	EPSD;PhosphoSitePlus	COSMIC	2.638	Down-regulation
CMGC_MAPK_JNK_MAPK8_ST	P05412	JUN	P45983	MAPK8	T93	P100L	100	Missense	distal	7	no	8.490	8.529	EPSD;PhosphoSitePlus	COSMIC	2.638	Up-regulation
CMGC_MAPK_JNK_MAPK8_ST	P05412	JUN	P45983	MAPK8	T93	P92Q	92	Missense	proximal	-1	no	8.490	8.495	EPSD;PhosphoSitePlus	COSMIC	2.638	Up-regulation
CMGC_MAPK_JNK_MAPK8_ST	P05412	JUN	P45983	MAPK8	T93	L98M	98	Missense	distal	5	no	8.490	8.481	EPSD;PhosphoSitePlus	COSMIC	2.638	Down-regulation
CMGC_MAPK_JNK_MAPK8_ST	P05412	JUN	P45983	MAPK8	T93	P94S	94	Missense	proximal	1	no	8.490	0.761	EPSD;PhosphoSitePlus	COSMIC	2.638	Loss
CMGC_MAPK_JNK_MAPK8_ST	P05412	JUN	P45983	MAPK8	T239	P240Q	240	Missense	proximal	1	no	5.188	-1.922	EPSD	COSMIC	2.638	Loss
CMGC_MAPK_JNK_MAPK8_ST	P05412	JUN	P45983	MAPK8	T239	T239I	239	Missense	central	0	yes	5.188	0.000	EPSD	COSMIC	2.638	Loss
CMGC_MAPK_JNK_MAPK8_ST	P05412	JUN	P45983	MAPK8	S243	P240Q	240	Missense	distal	-3	no	7.365	7.422	EPSD	COSMIC	2.638	Up-regulation
CMGC_MAPK_JNK_MAPK8_ST	P05412	JUN	P45983	MAPK8	S243	T239I	239	Missense	distal	-4	no	7.365	6.939	EPSD	COSMIC	2.638	Down-regulation
CMGC_MAPK_JNK_MAPK8_ST	Q14451	GRB7	P45983	MAPK8	S6	S11I	11	Missense	distal	5	no	8.652	8.701	EPSD	COSMIC	2.638	Up-regulation
CMGC_MAPK_JNK_MAPK8_ST	Q14451	GRB7	P45983	MAPK8	S6	P8L	8	Missense	proximal	2	no	8.652	8.576	EPSD	COSMIC	2.638	Down-regulation
CMGC_MAPK_JNK_MAPK8_ST	Q14451	GRB7	P45983	MAPK8	S6	L10F	10	Missense	distal	4	no	8.652	8.626	EPSD	COSMIC	2.638	Down-regulation
CMGC_MAPK_JNK_MAPK8_ST	Q14451	GRB7	P45983	MAPK8	S13	S11I	11	Missense	proximal	-2	no	6.680	6.682	EPSD	COSMIC	2.638	Up-regulation
CMGC_MAPK_JNK_MAPK8_ST	Q14451	GRB7	P45983	MAPK8	S13	P14L	14	Missense	proximal	1	no	6.680	-0.892	EPSD	COSMIC	2.638	Loss
CMGC_MAPK_JNK_MAPK8_ST	Q14451	GRB7	P45983	MAPK8	S13	D16N	16	Missense	distal	3	no	6.680	6.763	EPSD	COSMIC	2.638	Up-regulation
CMGC_MAPK_JNK_MAPK8_ST	Q14451	GRB7	P45983	MAPK8	S13	P8L	8	Missense	distal	-5	no	6.680	7.040	EPSD	COSMIC	2.638	Up-regulation
CMGC_MAPK_JNK_MAPK8_ST	Q14451	GRB7	P45983	MAPK8	S13	L10F	10	Missense	distal	-3	no	6.680	6.647	EPSD	COSMIC	2.638	Down-regulation
CMGC_MAPK_JNK_MAPK8_ST	Q14451	GRB7	P45983	MAPK8	T23	P28S	28	Missense	distal	5	no	7.643	7.560	EPSD	COSMIC	2.638	Down-regulation
CMGC_MAPK_JNK_MAPK8_ST	Q14451	GRB7	P45983	MAPK8	T23	T27I	27	Missense	distal	4	no	7.643	7.502	EPSD	COSMIC	2.638	Down-regulation
CMGC_MAPK_JNK_MAPK8_ST	Q14451	GRB7	P45983	MAPK8	T23	P30S	30	Missense	distal	7	no	7.643	7.604	EPSD	COSMIC	2.638	Down-regulation
CMGC_MAPK_JNK_MAPK8_ST	Q14451	GRB7	P45983	MAPK8	T23	R29Q	29	Missense	distal	6	no	7.643	7.689	EPSD	COSMIC;GDSC	2.638	Up-regulation
CMGC_MAPK_JNK_MAPK8_ST	Q14451	GRB7	P45983	MAPK8	T23	R29W	29	Missense	distal	6	no	7.643	7.633	EPSD	COSMIC	2.638	Down-regulation
CMGC_MAPK_JNK_MAPK8_ST	Q14451	GRB7	P45983	MAPK8	T23	D16N	16	Missense	distal	-7	no	7.643	7.649	EPSD	COSMIC	2.638	Up-regulation
CMGC_MAPK_JNK_MAPK8_ST	Q14451	GRB7	P45983	MAPK8	T27	P28S	28	Missense	proximal	1	no	7.100	-0.628	EPSD	COSMIC	2.638	Loss
CMGC_MAPK_JNK_MAPK8_ST	Q14451	GRB7	P45983	MAPK8	T27	T27I	27	Missense	central	0	yes	7.100	0.000	EPSD	COSMIC	2.638	Loss
CMGC_MAPK_JNK_MAPK8_ST	Q14451	GRB7	P45983	MAPK8	T27	P30S	30	Missense	distal	3	no	7.100	6.975	EPSD	COSMIC	2.638	Down-regulation
CMGC_MAPK_JNK_MAPK8_ST	Q14451	GRB7	P45983	MAPK8	T27	R29Q	29	Missense	proximal	2	no	7.100	7.275	EPSD	COSMIC;GDSC	2.638	Up-regulation
CMGC_MAPK_JNK_MAPK8_ST	Q14451	GRB7	P45983	MAPK8	T27	R29W	29	Missense	proximal	2	no	7.100	7.029	EPSD	COSMIC	2.638	Down-regulation
CMGC_MAPK_JNK_MAPK8_ST	Q14451	GRB7	P45983	MAPK8	T33	P28S	28	Missense	distal	-5	no	6.076	5.964	EPSD	COSMIC	2.638	Down-regulation
CMGC_MAPK_JNK_MAPK8_ST	Q14451	GRB7	P45983	MAPK8	T33	T27I	27	Missense	distal	-6	no	6.076	6.144	EPSD	COSMIC	2.638	Up-regulation
CMGC_MAPK_JNK_MAPK8_ST	Q14451	GRB7	P45983	MAPK8	T33	P30S	30	Missense	distal	-3	no	6.076	6.238	EPSD	COSMIC	2.638	Up-regulation
CMGC_MAPK_JNK_MAPK8_ST	Q14451	GRB7	P45983	MAPK8	T33	E37G	37	Missense	distal	4	no	6.076	5.783	EPSD	COSMIC	2.638	Down-regulation
CMGC_MAPK_JNK_MAPK8_ST	Q14451	GRB7	P45983	MAPK8	T33	E37Q	37	Missense	distal	4	no	6.076	5.995	EPSD	COSMIC	2.638	Down-regulation
CMGC_MAPK_JNK_MAPK8_ST	Q14451	GRB7	P45983	MAPK8	T33	R29Q	29	Missense	distal	-4	no	6.076	6.596	EPSD	COSMIC;GDSC	2.638	Up-regulation
CMGC_MAPK_JNK_MAPK8_ST	Q14451	GRB7	P45983	MAPK8	T33	R29W	29	Missense	distal	-4	no	6.076	5.833	EPSD	COSMIC	2.638	Down-regulation
CMGC_MAPK_JNK_MAPK8_ST	Q14451	GRB7	P45983	MAPK8	S76	P70L	70	Missense	distal	-6	no	7.552	7.643	EPSD	COSMIC	2.638	Up-regulation
CMGC_MAPK_JNK_MAPK8_ST	Q14451	GRB7	P45983	MAPK8	S76	E73K	73	Missense	distal	-3	no	7.552	7.578	EPSD	COSMIC	2.638	Up-regulation
CMGC_MAPK_JNK_MAPK8_ST	Q14451	GRB7	P45983	MAPK8	S76	P82S	82	Missense	distal	6	no	7.552	7.576	EPSD	COSMIC	2.638	Up-regulation
CMGC_MAPK_JNK_MAPK8_ST	Q14451	GRB7	P45983	MAPK8	S76	P70F	70	Missense	distal	-6	no	7.552	7.643	EPSD	COSMIC	2.638	Up-regulation
CMGC_MAPK_JNK_MAPK8_ST	Q14451	GRB7	P45983	MAPK8	S76	S76R	76	Missense	central	0	yes	7.552	0.000	EPSD	COSMIC	2.638	Loss
CMGC_MAPK_JNK_MAPK8_ST	Q14451	GRB7	P45983	MAPK8	S76	S76C	76	Missense	central	0	yes	7.552	0.000	EPSD	COSMIC	2.638	Loss
CMGC_MAPK_JNK_MAPK8_ST	Q14451	GRB7	P45983	MAPK8	S81	P82S	82	Missense	proximal	1	no	8.724	0.995	EPSD	COSMIC	2.638	Loss
CMGC_MAPK_JNK_MAPK8_ST	Q14451	GRB7	P45983	MAPK8	S81	G86C	86	Missense	distal	5	no	8.724	8.709	EPSD	COSMIC	2.638	Down-regulation
CMGC_MAPK_JNK_MAPK8_ST	Q14451	GRB7	P45983	MAPK8	S81	S76R	76	Missense	distal	-5	no	8.724	9.128	EPSD	COSMIC	2.638	Up-regulation
CMGC_MAPK_JNK_MAPK8_ST	Q14451	GRB7	P45983	MAPK8	S81	S76C	76	Missense	distal	-5	no	8.724	9.029	EPSD	COSMIC	2.638	Up-regulation
CMGC_MAPK_JNK_MAPK8_ST	Q14451	GRB7	P45983	MAPK8	T142	V146A	146	Missense	distal	4	no	2.619	3.138	EPSD	COSMIC	2.638	Gain
CMGC_MAPK_JNK_MAPK8_ST	Q14451	GRB7	P45983	MAPK8	T142	L138F	138	Missense	distal	-4	no	2.619	2.673	EPSD	COSMIC	2.638	Gain
CMGC_MAPK_JNK_MAPK8_ST	Q14451	GRB7	P45983	MAPK8	T142	A137V	137	Missense	distal	-5	no	2.619	3.160	EPSD	COSMIC	2.638	Gain
CMGC_MAPK_JNK_MAPK8_ST	Q14451	GRB7	P45983	MAPK8	S194	P195S	195	Missense	proximal	1	no	8.573	0.844	PhosphoSitePlus	COSMIC	2.638	Loss
CMGC_MAPK_JNK_MAPK8_ST	Q14451	GRB7	P45983	MAPK8	S194	S197F	197	Missense	distal	3	no	8.573	8.792	PhosphoSitePlus	COSMIC	2.638	Up-regulation
CMGC_MAPK_JNK_MAPK8_ST	Q14451	GRB7	P45983	MAPK8	S194	E189K	189	Missense	distal	-5	no	8.573	8.496	PhosphoSitePlus	COSMIC	2.638	Down-regulation
CMGC_MAPK_JNK_MAPK8_ST	Q14451	GRB7	P45983	MAPK8	S194	S197Y	197	Missense	distal	3	no	8.573	8.854	PhosphoSitePlus	COSMIC	2.638	Up-regulation
CMGC_MAPK_JNK_MAPK8_ST	Q14451	GRB7	P45983	MAPK8	S361	C358S	358	Missense	distal	-3	no	6.706	6.961	EPSD	COSMIC	2.638	Up-regulation
CMGC_MAPK_JNK_MAPK8_ST	Q14451	GRB7	P45983	MAPK8	S361	S361C	361	Missense	central	0	yes	6.706	0.000	EPSD	COSMIC	2.638	Loss
CMGC_MAPK_JNK_MAPK8_ST	Q14451	GRB7	P45983	MAPK8	S361	P363S	363	Missense	proximal	2	no	6.706	6.892	EPSD	COSMIC	2.638	Up-regulation
CMGC_MAPK_JNK_MAPK8_ST	Q14451	GRB7	P45983	MAPK8	S361	R365I	365	Missense	distal	4	no	6.706	6.882	EPSD	COSMIC	2.638	Up-regulation
CMGC_MAPK_JNK_MAPK8_ST	Q14451	GRB7	P45983	MAPK8	S361	S357C	357	Missense	distal	-4	no	6.706	5.939	EPSD	COSMIC	2.638	Down-regulation
CMGC_MAPK_JNK_MAPK8_ST	Q14451	GRB7	P45983	MAPK8	S361	L354V	354	Missense	distal	-7	no	6.706	6.708	EPSD	COSMIC	2.638	Up-regulation
CMGC_MAPK_JNK_MAPK8_ST	Q14451	GRB7	P45983	MAPK8	S361	S361F	361	Missense	central	0	yes	6.706	0.000	EPSD	COSMIC	2.638	Loss
CMGC_MAPK_JNK_MAPK8_ST	Q14451	GRB7	P45983	MAPK8	T371	L372P	372	Missense	proximal	1	no	-0.718	6.854	EPSD	COSMIC	2.638	Gain
CMGC_MAPK_JNK_MAPK8_ST	P30305	CDC25B	P45983	MAPK8	S42	A47P	47	Missense	distal	5	no	8.088	8.163	EPSD	COSMIC	2.638	Up-regulation
CMGC_MAPK_JNK_MAPK8_ST	P30305	CDC25B	P45983	MAPK8	S42	S36L	36	Missense	distal	-6	no	8.088	8.268	EPSD	COSMIC	2.638	Up-regulation
CMGC_MAPK_JNK_MAPK8_ST	P30305	CDC25B	P45983	MAPK8	S50	A47P	47	Missense	distal	-3	no	9.900	9.703	EPSD	COSMIC	2.638	Down-regulation
CMGC_MAPK_JNK_MAPK8_ST	P30305	CDC25B	P45983	MAPK8	S50	P51L	51	Missense	proximal	1	no	9.900	2.328	EPSD	COSMIC	2.638	Loss
CMGC_MAPK_JNK_MAPK8_ST	P30305	CDC25B	P45983	MAPK8	S50	Q57R	57	Missense	distal	7	no	9.900	9.946	EPSD	COSMIC	2.638	Up-regulation
CMGC_MAPK_JNK_MAPK8_ST	P30305	CDC25B	P45983	MAPK8	S50	A48T	48	Missense	proximal	-2	no	9.900	9.871	EPSD	COSMIC	2.638	Down-regulation
CMGC_MAPK_JNK_MAPK8_ST	P30305	CDC25B	P45983	MAPK8	S67	E68K	68	Missense	proximal	1	no	2.193	2.658	EPSD	COSMIC	2.638	Gain
CMGC_MAPK_JNK_MAPK8_ST	P30305	CDC25B	P45983	MAPK8	T69	E68K	68	Missense	proximal	-1	no	7.377	7.380	EPSD	COSMIC	2.638	Up-regulation
CMGC_MAPK_JNK_MAPK8_ST	P30305	CDC25B	P45983	MAPK8	T69	Q73H	73	Missense	distal	4	no	7.377	7.180	EPSD	COSMIC	2.638	Down-regulation
CMGC_MAPK_JNK_MAPK8_ST	P30305	CDC25B	P45983	MAPK8	S115	A109V	109	Missense	distal	-6	no	7.331	7.532	EPSD	COSMIC	2.638	Up-regulation
CMGC_MAPK_JNK_MAPK8_ST	P30305	CDC25B	P45983	MAPK8	S117	A124E	124	Missense	distal	7	no	7.637	7.631	EPSD	COSMIC	2.638	Down-regulation
CMGC_MAPK_JNK_MAPK8_ST	P30305	CDC25B	P45983	MAPK8	S160	V162L	162	Missense	proximal	2	no	7.307	7.339	EPSD	COSMIC	2.638	Up-regulation
CMGC_MAPK_JNK_MAPK8_ST	P30305	CDC25B	P45983	MAPK8	S188	A184V	184	Missense	distal	-4	no	3.282	2.426	EPSD	COSMIC	2.638	Loss
CMGC_MAPK_JNK_MAPK8_ST	P30305	CDC25B	P45983	MAPK8	S188	S188R	188	Missense	central	0	yes	3.282	0.000	EPSD	COSMIC	2.638	Loss
CMGC_MAPK_JNK_MAPK8_ST	P30305	CDC25B	P45983	MAPK8	S238	R241C	241	Missense	distal	3	no	7.003	6.986	EPSD	COSMIC	2.638	Down-regulation
CMGC_MAPK_JNK_MAPK8_ST	P30305	CDC25B	P45983	MAPK8	S238	L237H	237	Missense	proximal	-1	no	7.003	7.012	EPSD	COSMIC	2.638	Up-regulation
CMGC_MAPK_JNK_MAPK8_ST	P30305	CDC25B	P45983	MAPK8	S249	S249R	249	Missense	central	0	yes	8.352	0.000	EPSD	COSMIC	2.638	Loss
CMGC_MAPK_JNK_MAPK8_ST	P30305	CDC25B	P45983	MAPK8	S249	F256L	256	Missense	distal	7	no	8.352	8.355	EPSD	COSMIC;GDSC;CCLE	2.638	Up-regulation
CMGC_MAPK_JNK_MAPK8_ST	P30305	CDC25B	P45983	MAPK8	S249	A252V	252	Missense	distal	3	no	8.352	8.579	EPSD	COSMIC	2.638	Up-regulation
CMGC_MAPK_JNK_MAPK8_ST	P30305	CDC25B	P45983	MAPK8	S249	S249G	249	Missense	central	0	yes	8.352	0.000	EPSD	COSMIC	2.638	Loss
CMGC_MAPK_JNK_MAPK8_ST	P30305	CDC25B	P45983	MAPK8	S249	R255C	255	Missense	distal	6	no	8.352	8.364	EPSD	COSMIC	2.638	Up-regulation
CMGC_MAPK_JNK_MAPK8_ST	P30305	CDC25B	P45983	MAPK8	S321	S323N	323	Missense	proximal	2	no	9.454	9.192	EPSD	COSMIC	2.638	Down-regulation
CMGC_MAPK_JNK_MAPK8_ST	P30305	CDC25B	P45983	MAPK8	S321	P325L	325	Missense	distal	4	no	9.454	9.047	EPSD	COSMIC	2.638	Down-regulation
CMGC_MAPK_JNK_MAPK8_ST	P30305	CDC25B	P45983	MAPK8	S321	R320G	320	Missense	proximal	-1	no	9.454	9.455	EPSD	COSMIC	2.638	Up-regulation
CMGC_MAPK_JNK_MAPK8_ST	P30305	CDC25B	P45983	MAPK8	S321	S321F	321	Missense	central	0	yes	9.454	0.000	EPSD	COSMIC	2.638	Loss
CMGC_MAPK_JNK_MAPK8_ST	P30305	CDC25B	P45983	MAPK8	S321	C315W	315	Missense	distal	-6	no	9.454	9.506	EPSD	COSMIC;GDSC	2.638	Up-regulation
CMGC_MAPK_JNK_MAPK8_ST	P30305	CDC25B	P45983	MAPK8	S321	P322L	322	Missense	proximal	1	no	9.454	1.881	EPSD	COSMIC	2.638	Loss
CMGC_MAPK_JNK_MAPK8_ST	P30305	CDC25B	P45983	MAPK8	S321	R317W	317	Missense	distal	-4	no	9.454	9.210	EPSD	COSMIC	2.638	Down-regulation
CMGC_MAPK_JNK_MAPK8_ST	P30305	CDC25B	P45983	MAPK8	T344	R338W	338	Missense	distal	-6	no	5.844	5.870	EPSD	COSMIC	2.638	Up-regulation
CMGC_MAPK_JNK_MAPK8_ST	P30305	CDC25B	P45983	MAPK8	T344	P345S	345	Missense	proximal	1	no	5.844	-1.885	EPSD	COSMIC	2.638	Loss
CMGC_MAPK_JNK_MAPK8_ST	P30305	CDC25B	P45983	MAPK8	T344	D343G	343	Missense	proximal	-1	no	5.844	5.833	EPSD	COSMIC	2.638	Down-regulation
CMGC_MAPK_JNK_MAPK8_ST	P30305	CDC25B	P45983	MAPK8	T344	R350T	350	Missense	distal	6	no	5.844	5.901	EPSD	COSMIC	2.638	Up-regulation
CMGC_MAPK_JNK_MAPK8_ST	P30305	CDC25B	P45983	MAPK8	T355	R352Q	352	Missense	distal	-3	no	6.880	7.079	EPSD	COSMIC	2.638	Up-regulation
CMGC_MAPK_JNK_MAPK8_ST	P30305	CDC25B	P45983	MAPK8	T355	R350T	350	Missense	distal	-5	no	6.880	6.475	EPSD	COSMIC	2.638	Down-regulation
CMGC_MAPK_JNK_MAPK8_ST	P30305	CDC25B	P45983	MAPK8	S416	A422V	422	Missense	distal	6	no	6.895	6.820	EPSD	COSMIC	2.638	Down-regulation
CMGC_MAPK_JNK_MAPK8_ST	P30305	CDC25B	P45983	MAPK8	S416	Q410K	410	Missense	distal	-6	no	6.895	6.830	EPSD	COSMIC	2.638	Down-regulation
CMGC_MAPK_JNK_MAPK8_ST	P30305	CDC25B	P45983	MAPK8	S416	P417Q	417	Missense	proximal	1	no	6.895	-0.214	EPSD	COSMIC	2.638	Loss
CMGC_MAPK_JNK_MAPK8_ST	P30305	CDC25B	P45983	MAPK8	S416	L423F	423	Missense	distal	7	no	6.895	6.892	EPSD	COSMIC	2.638	Down-regulation
CMGC_MAPK_JNK_MAPK8_ST	P30305	CDC25B	P45983	MAPK8	S470	E464G	464	Missense	distal	-6	no	8.647	8.806	EPSD	COSMIC	2.638	Up-regulation
CMGC_MAPK_JNK_MAPK8_ST	P30305	CDC25B	P45983	MAPK8	S470	E464K	464	Missense	distal	-6	no	8.647	8.643	EPSD	COSMIC	2.638	Down-regulation
CMGC_MAPK_JNK_MAPK8_ST	P30305	CDC25B	P45983	MAPK8	S470	L477P	477	Missense	distal	7	no	8.647	8.608	EPSD	COSMIC	2.638	Down-regulation
CMGC_MAPK_JNK_MAPK8_ST	P30305	CDC25B	P45983	MAPK8	S470	A473V	473	Missense	distal	3	no	8.647	8.875	EPSD	COSMIC	2.638	Up-regulation
CMGC_MAPK_JNK_MAPK8_ST	P30305	CDC25B	P45983	MAPK8	S470	A463T	463	Missense	distal	-7	no	8.647	8.649	EPSD	COSMIC	2.638	Up-regulation
CMGC_MAPK_JNK_MAPK8_ST	P30305	CDC25B	P45983	MAPK8	S470	K469R	469	Missense	proximal	-1	no	8.647	8.615	EPSD	COSMIC	2.638	Down-regulation
CMGC_MAPK_JNK_MAPK8_ST	P30305	CDC25B	P45983	MAPK8	S476	L477P	477	Missense	proximal	1	no	0.227	7.799	EPSD	COSMIC	2.638	Gain
CMGC_MAPK_JNK_MAPK8_ST	Q13043	STK4	P45983	MAPK8	T187	V184M	184	Missense	distal	-3	no	6.998	7.066	EPSD	COSMIC	2.638	Up-regulation
CMGC_MAPK_JNK_MAPK8_ST	Q13043	STK4	P45983	MAPK8	T187	E194Q	194	Missense	distal	7	no	6.998	7.015	EPSD	COSMIC	2.638	Up-regulation
CMGC_MAPK_JNK_MAPK8_ST	Q13043	STK4	P45983	MAPK8	T187	G186R	186	Missense	proximal	-1	no	6.998	6.997	EPSD	COSMIC	2.638	Down-regulation
CMGC_MAPK_JNK_MAPK8_ST	Q13043	STK4	P45983	MAPK8	S265	K259T	259	Missense	distal	-6	no	8.206	8.243	EPSD	COSMIC	2.638	Up-regulation
CMGC_MAPK_JNK_MAPK8_ST	Q07820	MCL1	P45983	MAPK8	S64	G58S	58	Missense	distal	-6	no	10.145	9.994	PhosphoSitePlus;EPSD	COSMIC	2.638	Down-regulation
CMGC_MAPK_JNK_MAPK8_ST	Q07820	MCL1	P45983	MAPK8	S64	G59E	59	Missense	distal	-5	no	10.145	9.751	PhosphoSitePlus;EPSD	COSMIC	2.638	Down-regulation
CMGC_MAPK_JNK_MAPK8_ST	Q07820	MCL1	P45983	MAPK8	S64	P65L	65	Missense	proximal	1	no	10.145	2.573	PhosphoSitePlus;EPSD	COSMIC	2.638	Loss
CMGC_MAPK_JNK_MAPK8_ST	Q07820	MCL1	P45983	MAPK8	T70	D72G	72	Missense	proximal	2	no	6.137	6.071	EPSD	COSMIC	2.638	Down-regulation
CMGC_MAPK_JNK_MAPK8_ST	Q07820	MCL1	P45983	MAPK8	T70	P65L	65	Missense	distal	-5	no	6.137	6.497	EPSD	COSMIC	2.638	Up-regulation
CMGC_MAPK_JNK_MAPK8_ST	Q07820	MCL1	P45983	MAPK8	T70	A77V	77	Missense	distal	7	no	6.137	6.216	EPSD	COSMIC	2.638	Up-regulation
CMGC_MAPK_JNK_MAPK8_ST	Q07820	MCL1	P45983	MAPK8	T92	P93R	93	Missense	proximal	1	no	7.127	-0.010	EPSD	COSMIC	2.638	Loss
CMGC_MAPK_JNK_MAPK8_ST	Q07820	MCL1	P45983	MAPK8	T92	F99L	99	Missense	distal	7	no	7.127	7.130	EPSD	COSMIC	2.638	Up-regulation
CMGC_MAPK_JNK_MAPK8_ST	Q07820	MCL1	P45983	MAPK8	T92	P87L	87	Missense	distal	-5	no	7.127	7.487	EPSD	COSMIC	2.638	Up-regulation
CMGC_MAPK_JNK_MAPK8_ST	Q07820	MCL1	P45983	MAPK8	S121	L126M	126	Missense	distal	5	no	6.612	6.602	EPSD;PhosphoSitePlus	COSMIC	2.638	Down-regulation
CMGC_MAPK_JNK_MAPK8_ST	Q07820	MCL1	P45983	MAPK8	S121	A116P	116	Missense	distal	-5	no	6.612	6.740	EPSD;PhosphoSitePlus	COSMIC	2.638	Up-regulation
CMGC_MAPK_JNK_MAPK8_ST	Q07820	MCL1	P45983	MAPK8	S121	P122L	122	Missense	proximal	1	no	6.612	-0.961	EPSD;PhosphoSitePlus	COSMIC	2.638	Loss
CMGC_MAPK_JNK_MAPK8_ST	Q07820	MCL1	P45983	MAPK8	T163	E169K	169	Missense	distal	6	no	8.911	8.927	EPSD;PhosphoSitePlus	COSMIC	2.638	Up-regulation
CMGC_MAPK_JNK_MAPK8_ST	Q07820	MCL1	P45983	MAPK8	T163	P161F	161	Missense	proximal	-2	no	8.911	8.690	EPSD;PhosphoSitePlus	COSMIC	2.638	Down-regulation
CMGC_MAPK_JNK_MAPK8_ST	Q07820	MCL1	P45983	MAPK8	T163	P161H	161	Missense	proximal	-2	no	8.911	8.727	EPSD;PhosphoSitePlus	COSMIC	2.638	Down-regulation
CMGC_MAPK_JNK_MAPK8_ST	Q07820	MCL1	P45983	MAPK8	T163	G158R	158	Missense	distal	-5	no	8.911	8.939	EPSD;PhosphoSitePlus	COSMIC	2.638	Up-regulation
CMGC_MAPK_JNK_MAPK8_ST	Q07820	MCL1	P45983	MAPK8	T163	G158D	158	Missense	distal	-5	no	8.911	8.759	EPSD;PhosphoSitePlus	COSMIC	2.638	Down-regulation
CMGC_MAPK_JNK_MAPK8_ST	P30307	CDC25C	P45983	MAPK8	T48	L54V	54	Missense	distal	6	no	7.132	7.125	EPSD	COSMIC	2.638	Down-regulation
CMGC_MAPK_JNK_MAPK8_ST	P30307	CDC25C	P45983	MAPK8	T48	V50A	50	Missense	proximal	2	no	7.132	7.450	EPSD	COSMIC	2.638	Up-regulation
CMGC_MAPK_JNK_MAPK8_ST	P30307	CDC25C	P45983	MAPK8	T48	P49Q	49	Missense	proximal	1	no	7.132	0.023	EPSD	COSMIC	2.638	Loss
CMGC_MAPK_JNK_MAPK8_ST	P30307	CDC25C	P45983	MAPK8	T48	F53L	53	Missense	distal	5	no	7.132	7.138	EPSD	COSMIC	2.638	Up-regulation
CMGC_MAPK_JNK_MAPK8_ST	P30307	CDC25C	P45983	MAPK8	S61	L54V	54	Missense	distal	-7	no	3.281	3.283	EPSD	COSMIC	2.638	Up-regulation
CMGC_MAPK_JNK_MAPK8_ST	P30307	CDC25C	P45983	MAPK8	T67	R70L	70	Missense	distal	3	no	7.370	7.415	EPSD	COSMIC	2.638	Up-regulation
CMGC_MAPK_JNK_MAPK8_ST	P30307	CDC25C	P45983	MAPK8	S122	S122N	122	Missense	central	0	yes	7.676	0.000	EPSD	COSMIC	2.638	Loss
CMGC_MAPK_JNK_MAPK8_ST	P30307	CDC25C	P45983	MAPK8	T130	P131S	131	Missense	proximal	1	no	6.005	-1.723	EPSD	COSMIC	2.638	Loss
CMGC_MAPK_JNK_MAPK8_ST	P30307	CDC25C	P45983	MAPK8	T130	P131L	131	Missense	proximal	1	no	6.005	-1.567	EPSD	COSMIC;GDSC;CCLE	2.638	Loss
CMGC_MAPK_JNK_MAPK8_ST	P30307	CDC25C	P45983	MAPK8	T130	G137R	137	Missense	distal	7	no	6.005	6.004	EPSD	COSMIC	2.638	Down-regulation
CMGC_MAPK_JNK_MAPK8_ST	P30307	CDC25C	P45983	MAPK8	S168	S168F	168	Missense	central	0	yes	8.423	0.000	PhosphoSitePlus	COSMIC	2.638	Loss
CMGC_MAPK_JNK_MAPK8_ST	P30307	CDC25C	P45983	MAPK8	S168	S161L	161	Missense	distal	-7	no	8.423	8.441	PhosphoSitePlus	COSMIC	2.638	Up-regulation
CMGC_MAPK_JNK_MAPK8_ST	P30307	CDC25C	P45983	MAPK8	S214	S216L	216	Missense	proximal	2	no	8.343	8.081	EPSD	COSMIC	2.638	Down-regulation
CMGC_MAPK_JNK_MAPK8_ST	P30307	CDC25C	P45983	MAPK8	S214	G210R	210	Missense	distal	-4	no	8.343	8.430	EPSD	COSMIC	2.638	Up-regulation
CMGC_MAPK_JNK_MAPK8_ST	P30307	CDC25C	P45983	MAPK8	S247	S247F	247	Missense	central	0	yes	2.872	0.000	EPSD	COSMIC	2.638	Loss
CMGC_MAPK_JNK_MAPK8_ST	P30307	CDC25C	P45983	MAPK8	S247	Y245S	245	Missense	proximal	-2	no	2.872	3.000	EPSD	COSMIC	2.638	Up-regulation
CMGC_MAPK_JNK_MAPK8_ST	P30307	CDC25C	P45983	MAPK8	S247	K244T	244	Missense	distal	-3	no	2.872	2.775	EPSD	COSMIC	2.638	Down-regulation
CMGC_MAPK_JNK_MAPK8_ST	P30307	CDC25C	P45983	MAPK8	S247	G250E	250	Missense	distal	3	no	2.872	2.695	EPSD	COSMIC	2.638	Down-regulation
CMGC_MAPK_JNK_MAPK8_ST	P30307	CDC25C	P45983	MAPK8	S247	G250W	250	Missense	distal	3	no	2.872	2.914	EPSD	COSMIC	2.638	Up-regulation
CMGC_MAPK_JNK_MAPK8_ST	P30307	CDC25C	P45983	MAPK8	S247	S247C	247	Missense	central	0	yes	2.872	0.000	EPSD	COSMIC	2.638	Loss
CMGC_MAPK_JNK_MAPK8_ST	Q8WYQ5	DGCR8	P45983	MAPK8	S6	P9S	9	Missense	distal	3	no	8.332	8.207	EPSD	COSMIC	2.638	Down-regulation
CMGC_MAPK_JNK_MAPK8_ST	Q8WYQ5	DGCR8	P45983	MAPK8	S6	S6N	6	Missense	central	0	yes	8.332	0.000	EPSD	COSMIC	2.638	Loss
CMGC_MAPK_JNK_MAPK8_ST	Q8WYQ5	DGCR8	P45983	MAPK8	S8	P9S	9	Missense	proximal	1	no	7.596	-0.132	EPSD	COSMIC	2.638	Loss
CMGC_MAPK_JNK_MAPK8_ST	Q8WYQ5	DGCR8	P45983	MAPK8	S8	S6N	6	Missense	proximal	-2	no	7.596	7.479	EPSD	COSMIC	2.638	Down-regulation
CMGC_MAPK_JNK_MAPK8_ST	Q8WYQ5	DGCR8	P45983	MAPK8	S35	E33A	33	Missense	proximal	-2	no	7.738	7.760	EPSD	COSMIC	2.638	Up-regulation
CMGC_MAPK_JNK_MAPK8_ST	Q8WYQ5	DGCR8	P45983	MAPK8	S35	P39L	39	Missense	distal	4	no	7.738	7.331	EPSD	COSMIC	2.638	Down-regulation
CMGC_MAPK_JNK_MAPK8_ST	Q8WYQ5	DGCR8	P45983	MAPK8	S95	D88N	88	Missense	distal	-7	no	10.575	10.581	EPSD	COSMIC	2.638	Up-regulation
CMGC_MAPK_JNK_MAPK8_ST	Q8WYQ5	DGCR8	P45983	MAPK8	S95	R97H	97	Missense	proximal	2	no	10.575	10.633	EPSD	COSMIC	2.638	Up-regulation
CMGC_MAPK_JNK_MAPK8_ST	Q8WYQ5	DGCR8	P45983	MAPK8	S95	S92R	92	Missense	distal	-3	no	10.575	10.270	EPSD	COSMIC	2.638	Down-regulation
CMGC_MAPK_JNK_MAPK8_ST	Q8WYQ5	DGCR8	P45983	MAPK8	S109	S109F	109	Missense	central	0	yes	6.871	0.000	EPSD	COSMIC	2.638	Loss
CMGC_MAPK_JNK_MAPK8_ST	Q8WYQ5	DGCR8	P45983	MAPK8	S153	S156C	156	Missense	distal	3	no	7.348	7.513	PhosphoSitePlus	COSMIC	2.638	Up-regulation
CMGC_MAPK_JNK_MAPK8_ST	Q8WYQ5	DGCR8	P45983	MAPK8	T371	G374V	374	Missense	distal	3	no	6.340	6.396	EPSD	COSMIC	2.638	Up-regulation
CMGC_MAPK_JNK_MAPK8_ST	Q8WYQ5	DGCR8	P45983	MAPK8	T371	G374R	374	Missense	distal	3	no	6.340	6.333	EPSD	COSMIC	2.638	Down-regulation
CMGC_MAPK_JNK_MAPK8_ST	Q8WYQ5	DGCR8	P45983	MAPK8	T371	P372L	372	Missense	proximal	1	no	6.340	-1.232	EPSD	COSMIC	2.638	Loss
CMGC_MAPK_JNK_MAPK8_ST	Q8WYQ5	DGCR8	P45983	MAPK8	T371	P378L	378	Missense	distal	7	no	6.340	6.380	EPSD	COSMIC	2.638	Up-regulation
CMGC_MAPK_JNK_MAPK8_ST	Q8WYQ5	DGCR8	P45983	MAPK8	S377	G374V	374	Missense	distal	-3	no	7.335	7.222	EPSD	COSMIC	2.638	Down-regulation
CMGC_MAPK_JNK_MAPK8_ST	Q8WYQ5	DGCR8	P45983	MAPK8	S377	G374R	374	Missense	distal	-3	no	7.335	7.311	EPSD	COSMIC	2.638	Down-regulation
CMGC_MAPK_JNK_MAPK8_ST	Q8WYQ5	DGCR8	P45983	MAPK8	S377	P372L	372	Missense	distal	-5	no	7.335	7.695	EPSD	COSMIC	2.638	Up-regulation
CMGC_MAPK_JNK_MAPK8_ST	Q8WYQ5	DGCR8	P45983	MAPK8	S377	P378L	378	Missense	proximal	1	no	7.335	-0.238	EPSD	COSMIC	2.638	Loss
CMGC_MAPK_JNK_MAPK8_ST	Q8WYQ5	DGCR8	P45983	MAPK8	S619	E626K	626	Missense	distal	7	no	7.100	7.085	EPSD	COSMIC	2.638	Down-regulation
CMGC_MAPK_JNK_MAPK8_ST	Q8WYQ5	DGCR8	P45983	MAPK8	S619	Q622K	622	Missense	distal	3	no	7.100	7.003	EPSD	COSMIC	2.638	Down-regulation
CMGC_MAPK_JNK_MAPK8_ST	Q8N122	RPTOR	P45983	MAPK8	S8	S3Y	3	Missense	distal	-5	no	6.626	7.226	EPSD	COSMIC	2.638	Up-regulation
CMGC_MAPK_JNK_MAPK8_ST	Q8N122	RPTOR	P45983	MAPK8	S696	E689K	689	Missense	distal	-7	no	7.020	7.016	PhosphoSitePlus;EPSD	COSMIC	2.638	Down-regulation
CMGC_MAPK_JNK_MAPK8_ST	Q8N122	RPTOR	P45983	MAPK8	S696	S696Y	696	Missense	central	0	yes	7.020	0.000	PhosphoSitePlus;EPSD	COSMIC	2.638	Loss
CMGC_MAPK_JNK_MAPK8_ST	Q8N122	RPTOR	P45983	MAPK8	S696	A693T	693	Missense	distal	-3	no	7.020	6.966	PhosphoSitePlus;EPSD	COSMIC;GDSC;CCLE	2.638	Down-regulation
CMGC_MAPK_JNK_MAPK8_ST	Q8N122	RPTOR	P45983	MAPK8	S696	G702E	702	Missense	distal	6	no	7.020	7.078	PhosphoSitePlus;EPSD	COSMIC	2.638	Up-regulation
CMGC_MAPK_JNK_MAPK8_ST	Q8N122	RPTOR	P45983	MAPK8	S696	S696A	696	Missense	central	0	yes	7.020	0.000	PhosphoSitePlus;EPSD	COSMIC	2.638	Loss
CMGC_MAPK_JNK_MAPK8_ST	Q8N122	RPTOR	P45983	MAPK8	T706	P712L	712	Missense	distal	6	no	8.509	8.463	EPSD;PhosphoSitePlus	COSMIC	2.638	Down-regulation
CMGC_MAPK_JNK_MAPK8_ST	Q8N122	RPTOR	P45983	MAPK8	T706	D710N	710	Missense	distal	4	no	8.509	8.263	EPSD;PhosphoSitePlus	COSMIC	2.638	Down-regulation
CMGC_MAPK_JNK_MAPK8_ST	Q8N122	RPTOR	P45983	MAPK8	T706	R709G	709	Missense	distal	3	no	8.509	8.517	EPSD;PhosphoSitePlus	COSMIC	2.638	Up-regulation
CMGC_MAPK_JNK_MAPK8_ST	Q8N122	RPTOR	P45983	MAPK8	T706	G702E	702	Missense	distal	-4	no	8.509	9.254	EPSD;PhosphoSitePlus	COSMIC	2.638	Up-regulation
CMGC_MAPK_JNK_MAPK8_ST	Q8N122	RPTOR	P45983	MAPK8	S711	R718C	718	Missense	distal	7	no	6.618	6.607	EPSD	COSMIC;CCLE	2.638	Down-regulation
CMGC_MAPK_JNK_MAPK8_ST	Q8N122	RPTOR	P45983	MAPK8	S711	P712L	712	Missense	proximal	1	no	6.618	-0.955	EPSD	COSMIC	2.638	Loss
CMGC_MAPK_JNK_MAPK8_ST	Q8N122	RPTOR	P45983	MAPK8	S711	P715S	715	Missense	distal	4	no	6.618	6.643	EPSD	COSMIC	2.638	Up-regulation
CMGC_MAPK_JNK_MAPK8_ST	Q8N122	RPTOR	P45983	MAPK8	S711	D710N	710	Missense	proximal	-1	no	6.618	6.603	EPSD	COSMIC	2.638	Down-regulation
CMGC_MAPK_JNK_MAPK8_ST	Q8N122	RPTOR	P45983	MAPK8	S711	R709G	709	Missense	proximal	-2	no	6.618	6.631	EPSD	COSMIC	2.638	Up-regulation
CMGC_MAPK_JNK_MAPK8_ST	Q8N122	RPTOR	P45983	MAPK8	T714	R718C	718	Missense	distal	4	no	8.846	8.880	EPSD	COSMIC;CCLE	2.638	Up-regulation
CMGC_MAPK_JNK_MAPK8_ST	Q8N122	RPTOR	P45983	MAPK8	T714	P712L	712	Missense	proximal	-2	no	8.846	8.653	EPSD	COSMIC	2.638	Down-regulation
CMGC_MAPK_JNK_MAPK8_ST	Q8N122	RPTOR	P45983	MAPK8	T714	P715S	715	Missense	proximal	1	no	8.846	1.117	EPSD	COSMIC	2.638	Loss
CMGC_MAPK_JNK_MAPK8_ST	Q8N122	RPTOR	P45983	MAPK8	T714	D710N	710	Missense	distal	-4	no	8.846	8.539	EPSD	COSMIC	2.638	Down-regulation
CMGC_MAPK_JNK_MAPK8_ST	Q8N122	RPTOR	P45983	MAPK8	T714	S719Y	719	Missense	distal	5	no	8.846	8.953	EPSD	COSMIC	2.638	Up-regulation
CMGC_MAPK_JNK_MAPK8_ST	Q8N122	RPTOR	P45983	MAPK8	T714	S721N	721	Missense	distal	7	no	8.846	8.915	EPSD	COSMIC	2.638	Up-regulation
CMGC_MAPK_JNK_MAPK8_ST	Q8N122	RPTOR	P45983	MAPK8	T714	V720L	720	Missense	distal	6	no	8.846	8.853	EPSD	COSMIC	2.638	Up-regulation
CMGC_MAPK_JNK_MAPK8_ST	Q8N122	RPTOR	P45983	MAPK8	T714	R709G	709	Missense	distal	-5	no	8.846	8.818	EPSD	COSMIC	2.638	Down-regulation
CMGC_MAPK_JNK_MAPK8_ST	Q8N122	RPTOR	P45983	MAPK8	S771	A765T	765	Missense	distal	-6	no	6.735	6.757	EPSD	COSMIC	2.638	Up-regulation
CMGC_MAPK_JNK_MAPK8_ST	Q8N122	RPTOR	P45983	MAPK8	S771	E775Q	775	Missense	distal	4	no	6.735	6.654	EPSD	COSMIC	2.638	Down-regulation
CMGC_MAPK_JNK_MAPK8_ST	Q8N122	RPTOR	P45983	MAPK8	S836	A838S	838	Missense	proximal	2	no	3.092	3.067	EPSD	COSMIC;GDSC;CCLE	2.638	Down-regulation
CMGC_MAPK_JNK_MAPK8_ST	Q8N122	RPTOR	P45983	MAPK8	S836	A841V	841	Missense	distal	5	no	3.092	3.164	EPSD	COSMIC	2.638	Up-regulation
CMGC_MAPK_JNK_MAPK8_ST	Q8N122	RPTOR	P45983	MAPK8	S836	V829M	829	Missense	distal	-7	no	3.092	3.088	EPSD	COSMIC	2.638	Down-regulation
CMGC_MAPK_JNK_MAPK8_ST	Q8N122	RPTOR	P45983	MAPK8	S859	P861L	861	Missense	proximal	2	no	4.390	4.314	EPSD	COSMIC	2.638	Down-regulation
CMGC_MAPK_JNK_MAPK8_ST	Q8N122	RPTOR	P45983	MAPK8	S859	A862T	862	Missense	distal	3	no	4.390	4.400	EPSD	COSMIC	2.638	Up-regulation
CMGC_MAPK_JNK_MAPK8_ST	Q8N122	RPTOR	P45983	MAPK8	S859	S854A	854	Missense	distal	-5	no	4.390	4.374	EPSD	COSMIC	2.638	Down-regulation
CMGC_MAPK_JNK_MAPK8_ST	Q8N122	RPTOR	P45983	MAPK8	S863	K867R	867	Missense	distal	4	no	9.337	8.942	EPSD;PhosphoSitePlus	COSMIC	2.638	Down-regulation
CMGC_MAPK_JNK_MAPK8_ST	Q8N122	RPTOR	P45983	MAPK8	S863	G868S	868	Missense	distal	5	no	9.337	9.269	EPSD;PhosphoSitePlus	COSMIC	2.638	Down-regulation
CMGC_MAPK_JNK_MAPK8_ST	Q8N122	RPTOR	P45983	MAPK8	S863	P861L	861	Missense	proximal	-2	no	9.337	9.144	EPSD;PhosphoSitePlus	COSMIC	2.638	Down-regulation
CMGC_MAPK_JNK_MAPK8_ST	Q8N122	RPTOR	P45983	MAPK8	S863	V869M	869	Missense	distal	6	no	9.337	9.352	EPSD;PhosphoSitePlus	COSMIC	2.638	Up-regulation
CMGC_MAPK_JNK_MAPK8_ST	Q8N122	RPTOR	P45983	MAPK8	S863	A862T	862	Missense	proximal	-1	no	9.337	9.336	EPSD;PhosphoSitePlus	COSMIC	2.638	Down-regulation
CMGC_MAPK_JNK_MAPK8_ST	Q8N122	RPTOR	P45983	MAPK8	S877	A874V	874	Missense	distal	-3	no	9.094	8.664	EPSD	COSMIC;GDSC;CCLE	2.638	Down-regulation
CMGC_MAPK_JNK_MAPK8_ST	Q8N122	RPTOR	P45983	MAPK8	S877	P878S	878	Missense	proximal	1	no	9.094	1.365	EPSD	COSMIC	2.638	Loss
CMGC_MAPK_JNK_MAPK8_ST	Q8N122	RPTOR	P45983	MAPK8	S877	P879S	879	Missense	proximal	2	no	9.094	9.279	EPSD	COSMIC	2.638	Up-regulation
CMGC_MAPK_JNK_MAPK8_ST	Q8N122	RPTOR	P45983	MAPK8	S877	A880S	880	Missense	distal	3	no	9.094	9.075	EPSD	COSMIC	2.638	Down-regulation
CMGC_MAPK_JNK_MAPK8_ST	Q8N122	RPTOR	P45983	MAPK8	S877	P878L	878	Missense	proximal	1	no	9.094	1.521	EPSD	COSMIC	2.638	Loss
CMGC_MAPK_JNK_MAPK8_ST	Q8N122	RPTOR	P45983	MAPK8	S881	A874V	874	Missense	distal	-7	no	3.451	3.469	EPSD	COSMIC;GDSC;CCLE	2.638	Up-regulation
CMGC_MAPK_JNK_MAPK8_ST	Q8N122	RPTOR	P45983	MAPK8	S881	P878S	878	Missense	distal	-3	no	3.451	3.613	EPSD	COSMIC	2.638	Up-regulation
CMGC_MAPK_JNK_MAPK8_ST	Q8N122	RPTOR	P45983	MAPK8	S881	P879S	879	Missense	proximal	-2	no	3.451	3.346	EPSD	COSMIC	2.638	Down-regulation
CMGC_MAPK_JNK_MAPK8_ST	Q8N122	RPTOR	P45983	MAPK8	S881	A880S	880	Missense	proximal	-1	no	3.451	3.449	EPSD	COSMIC	2.638	Down-regulation
CMGC_MAPK_JNK_MAPK8_ST	Q8N122	RPTOR	P45983	MAPK8	S881	P878L	878	Missense	distal	-3	no	3.451	3.272	EPSD	COSMIC	2.638	Down-regulation
CMGC_MAPK_JNK_MAPK8_ST	Q8N122	RPTOR	P45983	MAPK8	S898	S898N	898	Missense	central	0	yes	3.303	0.000	EPSD	COSMIC	2.638	Loss
CMGC_MAPK_JNK_MAPK8_ST	Q8N122	RPTOR	P45983	MAPK8	S898	R899L	899	Missense	proximal	1	no	3.303	2.867	EPSD	COSMIC	2.638	Down-regulation
CMGC_MAPK_JNK_MAPK8_ST	Q8N122	RPTOR	P45983	MAPK8	S898	R905L	905	Missense	distal	7	no	3.303	3.319	EPSD	COSMIC	2.638	Up-regulation
CMGC_MAPK_JNK_MAPK8_ST	Q8N122	RPTOR	P45983	MAPK8	S898	D891Y	891	Missense	distal	-7	no	3.303	3.316	EPSD	COSMIC	2.638	Up-regulation
CMGC_MAPK_JNK_MAPK8_ST	Q8N122	RPTOR	P45983	MAPK8	S898	R905W	905	Missense	distal	7	no	3.303	3.317	EPSD	COSMIC	2.638	Up-regulation
CMGC_MAPK_JNK_MAPK8_ST	Q8N122	RPTOR	P45983	MAPK8	S898	D900A	900	Missense	proximal	2	no	3.303	3.464	EPSD	COSMIC	2.638	Up-regulation
CMGC_MAPK_JNK_MAPK8_ST	Q8N122	RPTOR	P45983	MAPK8	T917	P924T	924	Missense	distal	7	no	6.949	6.918	EPSD	COSMIC	2.638	Down-regulation
CMGC_MAPK_JNK_MAPK8_ST	Q8N122	RPTOR	P45983	MAPK8	T917	Y916C	916	Missense	proximal	-1	no	6.949	6.967	EPSD	COSMIC;GDSC;CCLE	2.638	Up-regulation
CMGC_MAPK_JNK_MAPK8_ST	Q8N122	RPTOR	P45983	MAPK8	T917	P911L	911	Missense	distal	-6	no	6.949	7.040	EPSD	COSMIC	2.638	Up-regulation
CMGC_MAPK_JNK_MAPK8_ST	Q8N122	RPTOR	P45983	MAPK8	T917	G910D	910	Missense	distal	-7	no	6.949	6.944	EPSD	COSMIC	2.638	Down-regulation
CMGC_MAPK_JNK_MAPK8_ST	Q8N122	RPTOR	P45983	MAPK8	T917	Q922R	922	Missense	distal	5	no	6.949	7.000	EPSD	COSMIC	2.638	Up-regulation
CMGC_MAPK_JNK_MAPK8_ST	P04637	TP53	P45983	MAPK8	S6	V10I	10	Missense	distal	4	no	2.363	2.693	EPSD	COSMIC	2.638	Gain
CMGC_MAPK_JNK_MAPK8_ST	P04637	TP53	P45983	MAPK8	S20	S20L	20	Missense	central	0	yes	4.275	0.000	PhosphoSitePlus;EPSD	COSMIC	2.638	Loss
CMGC_MAPK_JNK_MAPK8_ST	P04637	TP53	P45983	MAPK8	S20	Q16L	16	Missense	distal	-4	no	4.275	3.564	PhosphoSitePlus;EPSD	COSMIC;GDSC;CCLE	2.638	Down-regulation
CMGC_MAPK_JNK_MAPK8_ST	P04637	TP53	P45983	MAPK8	S20	P13S	13	Missense	distal	-7	no	4.275	4.269	PhosphoSitePlus;EPSD	COSMIC	2.638	Down-regulation
CMGC_MAPK_JNK_MAPK8_ST	P04637	TP53	P45983	MAPK8	S20	E17K	17	Missense	distal	-3	no	4.275	4.301	PhosphoSitePlus;EPSD	COSMIC	2.638	Up-regulation
CMGC_MAPK_JNK_MAPK8_ST	P04637	TP53	P45983	MAPK8	S20	P13L	13	Missense	distal	-7	no	4.275	4.286	PhosphoSitePlus;EPSD	COSMIC	2.638	Up-regulation
CMGC_MAPK_JNK_MAPK8_ST	P04637	TP53	P45983	MAPK8	S20	L26P	26	Missense	distal	6	no	4.275	4.322	PhosphoSitePlus;EPSD	COSMIC	2.638	Up-regulation
CMGC_MAPK_JNK_MAPK8_ST	P04637	TP53	P45983	MAPK8	S20	T18A	18	Missense	proximal	-2	no	4.275	4.305	PhosphoSitePlus;EPSD	COSMIC	2.638	Up-regulation
CMGC_MAPK_JNK_MAPK8_ST	P04637	TP53	P45983	MAPK8	S20	F19S	19	Missense	proximal	-1	no	4.275	4.304	PhosphoSitePlus;EPSD	COSMIC	2.638	Up-regulation
CMGC_MAPK_JNK_MAPK8_ST	P04637	TP53	P45983	MAPK8	S20	E17V	17	Missense	distal	-3	no	4.275	3.829	PhosphoSitePlus;EPSD	COSMIC	2.638	Down-regulation
CMGC_MAPK_JNK_MAPK8_ST	P04637	TP53	P45983	MAPK8	S20	P27T	27	Missense	distal	7	no	4.275	4.244	PhosphoSitePlus;EPSD	COSMIC	2.638	Down-regulation
CMGC_MAPK_JNK_MAPK8_ST	P04637	TP53	P45983	MAPK8	S20	T18I	18	Missense	proximal	-2	no	4.275	4.251	PhosphoSitePlus;EPSD	COSMIC	2.638	Down-regulation
CMGC_MAPK_JNK_MAPK8_ST	P04637	TP53	P45983	MAPK8	S20	T18K	18	Missense	proximal	-2	no	4.275	4.280	PhosphoSitePlus;EPSD	COSMIC	2.638	Up-regulation
CMGC_MAPK_JNK_MAPK8_ST	P04637	TP53	P45983	MAPK8	S20	T18R	18	Missense	proximal	-2	no	4.275	4.171	PhosphoSitePlus;EPSD	COSMIC	2.638	Down-regulation
CMGC_MAPK_JNK_MAPK8_ST	P04637	TP53	P45983	MAPK8	S20	S15I	15	Missense	distal	-5	no	4.275	4.479	PhosphoSitePlus;EPSD	COSMIC	2.638	Up-regulation
CMGC_MAPK_JNK_MAPK8_ST	P04637	TP53	P45983	MAPK8	S33	M40I	40	Missense	distal	7	no	7.176	7.149	EPSD	COSMIC	2.638	Down-regulation
CMGC_MAPK_JNK_MAPK8_ST	P04637	TP53	P45983	MAPK8	S33	V31I	31	Missense	proximal	-2	no	7.176	7.314	EPSD	COSMIC;GDSC;CCLE	2.638	Up-regulation
CMGC_MAPK_JNK_MAPK8_ST	P04637	TP53	P45983	MAPK8	S33	P36L	36	Missense	distal	3	no	7.176	7.278	EPSD	COSMIC;GDSC;CCLE	2.638	Up-regulation
CMGC_MAPK_JNK_MAPK8_ST	P04637	TP53	P45983	MAPK8	S33	L35F	35	Missense	proximal	2	no	7.176	7.167	EPSD	COSMIC	2.638	Down-regulation
CMGC_MAPK_JNK_MAPK8_ST	P04637	TP53	P45983	MAPK8	S33	Q38L	38	Missense	distal	5	no	7.176	7.238	EPSD	COSMIC	2.638	Up-regulation
CMGC_MAPK_JNK_MAPK8_ST	P04637	TP53	P45983	MAPK8	S33	S37T	37	Missense	distal	4	no	7.176	7.127	EPSD	COSMIC	2.638	Down-regulation
CMGC_MAPK_JNK_MAPK8_ST	P04637	TP53	P45983	MAPK8	S33	L26P	26	Missense	distal	-7	no	7.176	7.165	EPSD	COSMIC	2.638	Down-regulation
CMGC_MAPK_JNK_MAPK8_ST	P04637	TP53	P45983	MAPK8	S33	P36S	36	Missense	distal	3	no	7.176	7.051	EPSD	COSMIC;GDSC;CCLE	2.638	Down-regulation
CMGC_MAPK_JNK_MAPK8_ST	P04637	TP53	P45983	MAPK8	S33	A39V	39	Missense	distal	6	no	7.176	7.101	EPSD	COSMIC	2.638	Down-regulation
CMGC_MAPK_JNK_MAPK8_ST	P04637	TP53	P45983	MAPK8	S33	A39S	39	Missense	distal	6	no	7.176	7.180	EPSD	COSMIC	2.638	Up-regulation
CMGC_MAPK_JNK_MAPK8_ST	P04637	TP53	P45983	MAPK8	S33	N30K	30	Missense	distal	-3	no	7.176	7.608	EPSD	COSMIC	2.638	Up-regulation
CMGC_MAPK_JNK_MAPK8_ST	P04637	TP53	P45983	MAPK8	S33	A39T	39	Missense	distal	6	no	7.176	7.177	EPSD	COSMIC	2.638	Up-regulation
CMGC_MAPK_JNK_MAPK8_ST	P04637	TP53	P45983	MAPK8	S33	P27T	27	Missense	distal	-6	no	7.176	7.113	EPSD	COSMIC	2.638	Down-regulation
CMGC_MAPK_JNK_MAPK8_ST	P04637	TP53	P45983	MAPK8	S33	P36R	36	Missense	distal	3	no	7.176	7.233	EPSD	COSMIC	2.638	Up-regulation
CMGC_MAPK_JNK_MAPK8_ST	P04637	TP53	P45983	MAPK8	S33	L35R	35	Missense	proximal	2	no	7.176	7.197	EPSD	COSMIC	2.638	Up-regulation
CMGC_MAPK_JNK_MAPK8_ST	P04637	TP53	P45983	MAPK8	S33	L35H	35	Missense	proximal	2	no	7.176	7.255	EPSD	COSMIC	2.638	Up-regulation
CMGC_MAPK_JNK_MAPK8_ST	P04637	TP53	P45983	MAPK8	S33	L35P	35	Missense	proximal	2	no	7.176	7.253	EPSD	COSMIC	2.638	Up-regulation
CMGC_MAPK_JNK_MAPK8_ST	P04637	TP53	P45983	MAPK8	S33	L35I	35	Missense	proximal	2	no	7.176	7.316	EPSD	COSMIC	2.638	Up-regulation
CMGC_MAPK_JNK_MAPK8_ST	P04637	TP53	P45983	MAPK8	S33	L35V	35	Missense	proximal	2	no	7.176	7.145	EPSD	COSMIC	2.638	Down-regulation
CMGC_MAPK_JNK_MAPK8_ST	P04637	TP53	P45983	MAPK8	S46	M40I	40	Missense	distal	-6	no	8.038	7.967	EPSD	COSMIC	2.638	Down-regulation
CMGC_MAPK_JNK_MAPK8_ST	P04637	TP53	P45983	MAPK8	S46	W53C	53	Missense	distal	7	no	8.038	8.014	EPSD	COSMIC	2.638	Down-regulation
CMGC_MAPK_JNK_MAPK8_ST	P04637	TP53	P45983	MAPK8	S46	W53G	53	Missense	distal	7	no	8.038	8.026	EPSD	COSMIC	2.638	Down-regulation
CMGC_MAPK_JNK_MAPK8_ST	P04637	TP53	P45983	MAPK8	S46	S46F	46	Missense	central	0	yes	8.038	0.000	EPSD	COSMIC	2.638	Loss
CMGC_MAPK_JNK_MAPK8_ST	P04637	TP53	P45983	MAPK8	S46	D49Y	49	Missense	distal	3	no	8.038	8.199	EPSD	COSMIC	2.638	Up-regulation
CMGC_MAPK_JNK_MAPK8_ST	P04637	TP53	P45983	MAPK8	S46	P47L	47	Missense	proximal	1	no	8.038	0.466	EPSD	COSMIC	2.638	Loss
CMGC_MAPK_JNK_MAPK8_ST	P04637	TP53	P45983	MAPK8	S46	D49H	49	Missense	distal	3	no	8.038	8.082	EPSD	COSMIC;GDSC;CCLE	2.638	Up-regulation
CMGC_MAPK_JNK_MAPK8_ST	P04637	TP53	P45983	MAPK8	S46	P47S	47	Missense	proximal	1	no	8.038	0.309	EPSD	COSMIC	2.638	Loss
CMGC_MAPK_JNK_MAPK8_ST	P04637	TP53	P45983	MAPK8	S46	D41N	41	Missense	distal	-5	no	8.038	8.245	EPSD	COSMIC	2.638	Up-regulation
CMGC_MAPK_JNK_MAPK8_ST	P04637	TP53	P45983	MAPK8	S46	D48H	48	Missense	proximal	2	no	8.038	7.991	EPSD	COSMIC	2.638	Down-regulation
CMGC_MAPK_JNK_MAPK8_ST	P04637	TP53	P45983	MAPK8	S46	D49N	49	Missense	distal	3	no	8.038	8.121	EPSD	COSMIC	2.638	Up-regulation
CMGC_MAPK_JNK_MAPK8_ST	P04637	TP53	P45983	MAPK8	S46	M44I	44	Missense	proximal	-2	no	8.038	8.130	EPSD	COSMIC	2.638	Up-regulation
CMGC_MAPK_JNK_MAPK8_ST	P04637	TP53	P45983	MAPK8	S46	Q52H	52	Missense	distal	6	no	8.038	8.004	EPSD	COSMIC	2.638	Down-regulation
CMGC_MAPK_JNK_MAPK8_ST	P04637	TP53	P45983	MAPK8	S46	D49V	49	Missense	distal	3	no	8.038	8.164	EPSD	COSMIC	2.638	Up-regulation
CMGC_MAPK_JNK_MAPK8_ST	P04637	TP53	P45983	MAPK8	S46	A39V	39	Missense	distal	-7	no	8.038	8.056	EPSD	COSMIC	2.638	Up-regulation
CMGC_MAPK_JNK_MAPK8_ST	P04637	TP53	P45983	MAPK8	S46	D42Y	42	Missense	distal	-4	no	8.038	7.371	EPSD	COSMIC	2.638	Down-regulation
CMGC_MAPK_JNK_MAPK8_ST	P04637	TP53	P45983	MAPK8	S46	M44R	44	Missense	proximal	-2	no	8.038	8.051	EPSD	COSMIC	2.638	Up-regulation
CMGC_MAPK_JNK_MAPK8_ST	P04637	TP53	P45983	MAPK8	S46	S46P	46	Missense	central	0	yes	8.038	0.000	EPSD	COSMIC	2.638	Loss
CMGC_MAPK_JNK_MAPK8_ST	P04637	TP53	P45983	MAPK8	S46	M44V	44	Missense	proximal	-2	no	8.038	7.993	EPSD	COSMIC	2.638	Down-regulation
CMGC_MAPK_JNK_MAPK8_ST	P04637	TP53	P45983	MAPK8	S46	L45P	45	Missense	proximal	-1	no	8.038	8.057	EPSD	COSMIC	2.638	Up-regulation
CMGC_MAPK_JNK_MAPK8_ST	P04637	TP53	P45983	MAPK8	S46	M44T	44	Missense	proximal	-2	no	8.038	8.154	EPSD	COSMIC	2.638	Up-regulation
CMGC_MAPK_JNK_MAPK8_ST	P04637	TP53	P45983	MAPK8	S46	A39T	39	Missense	distal	-7	no	8.038	8.039	EPSD	COSMIC	2.638	Up-regulation
CMGC_MAPK_JNK_MAPK8_ST	P04637	TP53	P45983	MAPK8	S46	L43F	43	Missense	distal	-3	no	8.038	8.005	EPSD	COSMIC	2.638	Down-regulation
CMGC_MAPK_JNK_MAPK8_ST	P04637	TP53	P45983	MAPK8	S46	D41H	41	Missense	distal	-5	no	8.038	8.122	EPSD	COSMIC	2.638	Up-regulation
CMGC_MAPK_JNK_MAPK8_ST	P04637	TP53	P45983	MAPK8	S46	D49E	49	Missense	distal	3	no	8.038	7.930	EPSD	COSMIC	2.638	Down-regulation
CMGC_MAPK_JNK_MAPK8_ST	P04637	TP53	P45983	MAPK8	S46	D49G	49	Missense	distal	3	no	8.038	8.108	EPSD	COSMIC	2.638	Up-regulation
CMGC_MAPK_JNK_MAPK8_ST	P04637	TP53	P45983	MAPK8	S46	D48A	48	Missense	proximal	2	no	8.038	8.199	EPSD	COSMIC	2.638	Up-regulation
CMGC_MAPK_JNK_MAPK8_ST	P04637	TP53	P45983	MAPK8	S46	D48Y	48	Missense	proximal	2	no	8.038	7.797	EPSD	COSMIC	2.638	Down-regulation
CMGC_MAPK_JNK_MAPK8_ST	P04637	TP53	P45983	MAPK8	S46	D48E	48	Missense	proximal	2	no	8.038	8.238	EPSD	COSMIC	2.638	Up-regulation
CMGC_MAPK_JNK_MAPK8_ST	P04637	TP53	P45983	MAPK8	S46	D49I	49	Missense	distal	3	no	8.038	8.042	EPSD	COSMIC	2.638	Up-regulation
CMGC_MAPK_JNK_MAPK8_ST	P04637	TP53	P45983	MAPK8	S46	D41E	41	Missense	distal	-5	no	8.038	7.795	EPSD	COSMIC	2.638	Down-regulation
CMGC_MAPK_JNK_MAPK8_ST	P04637	TP53	P45983	MAPK8	T81	P77A	77	Missense	distal	-4	no	7.682	8.170	EPSD;PhosphoSitePlus	COSMIC	2.638	Up-regulation
CMGC_MAPK_JNK_MAPK8_ST	P04637	TP53	P45983	MAPK8	T81	A76T	76	Missense	distal	-5	no	7.682	7.699	EPSD;PhosphoSitePlus	COSMIC	2.638	Up-regulation
CMGC_MAPK_JNK_MAPK8_ST	P04637	TP53	P45983	MAPK8	T81	A83T	83	Missense	proximal	2	no	7.682	7.661	EPSD;PhosphoSitePlus	COSMIC	2.638	Down-regulation
CMGC_MAPK_JNK_MAPK8_ST	P04637	TP53	P45983	MAPK8	T81	T81I	81	Missense	central	0	yes	7.682	0.000	EPSD;PhosphoSitePlus	COSMIC	2.638	Loss
CMGC_MAPK_JNK_MAPK8_ST	P04637	TP53	P45983	MAPK8	T81	A84V	84	Missense	distal	3	no	7.682	7.910	EPSD;PhosphoSitePlus	COSMIC	2.638	Up-regulation
CMGC_MAPK_JNK_MAPK8_ST	P04637	TP53	P45983	MAPK8	T81	P80L	80	Missense	proximal	-1	no	7.682	7.664	EPSD;PhosphoSitePlus	COSMIC	2.638	Down-regulation
CMGC_MAPK_JNK_MAPK8_ST	P04637	TP53	P45983	MAPK8	T81	A86V	86	Missense	distal	5	no	7.682	7.755	EPSD;PhosphoSitePlus	COSMIC	2.638	Up-regulation
CMGC_MAPK_JNK_MAPK8_ST	P04637	TP53	P45983	MAPK8	T81	P85S	85	Missense	distal	4	no	7.682	7.707	EPSD;PhosphoSitePlus	COSMIC	2.638	Up-regulation
CMGC_MAPK_JNK_MAPK8_ST	P04637	TP53	P45983	MAPK8	T81	A79T	79	Missense	proximal	-2	no	7.682	7.653	EPSD;PhosphoSitePlus	COSMIC	2.638	Down-regulation
CMGC_MAPK_JNK_MAPK8_ST	P04637	TP53	P45983	MAPK8	T81	A84G	84	Missense	distal	3	no	7.682	7.854	EPSD;PhosphoSitePlus	COSMIC	2.638	Up-regulation
CMGC_MAPK_JNK_MAPK8_ST	P04637	TP53	P45983	MAPK8	T81	A78V	78	Missense	distal	-3	no	7.682	7.253	EPSD;PhosphoSitePlus	COSMIC	2.638	Down-regulation
CMGC_MAPK_JNK_MAPK8_ST	P04637	TP53	P45983	MAPK8	T81	A78S	78	Missense	distal	-3	no	7.682	7.647	EPSD;PhosphoSitePlus	COSMIC	2.638	Down-regulation
CMGC_MAPK_JNK_MAPK8_ST	P04637	TP53	P45983	MAPK8	T81	P87L	87	Missense	distal	6	no	7.682	7.635	EPSD;PhosphoSitePlus	COSMIC	2.638	Down-regulation
CMGC_MAPK_JNK_MAPK8_ST	P04637	TP53	P45983	MAPK8	T81	P85L	85	Missense	distal	4	no	7.682	7.275	EPSD;PhosphoSitePlus	COSMIC	2.638	Down-regulation
CMGC_MAPK_JNK_MAPK8_ST	P04637	TP53	P45983	MAPK8	T81	P82S	82	Missense	proximal	1	no	7.682	-0.046	EPSD;PhosphoSitePlus	COSMIC	2.638	Loss
CMGC_MAPK_JNK_MAPK8_ST	P04637	TP53	P45983	MAPK8	T81	P77S	77	Missense	distal	-4	no	7.682	8.347	EPSD;PhosphoSitePlus	COSMIC	2.638	Up-regulation
CMGC_MAPK_JNK_MAPK8_ST	P04637	TP53	P45983	MAPK8	T81	P80S	80	Missense	proximal	-1	no	7.682	7.692	EPSD;PhosphoSitePlus	COSMIC	2.638	Up-regulation
CMGC_MAPK_JNK_MAPK8_ST	P04637	TP53	P45983	MAPK8	T81	A84T	84	Missense	distal	3	no	7.682	7.692	EPSD;PhosphoSitePlus	COSMIC	2.638	Up-regulation
CMGC_MAPK_JNK_MAPK8_ST	P04637	TP53	P45983	MAPK8	T81	A83E	83	Missense	proximal	2	no	7.682	7.721	EPSD;PhosphoSitePlus	COSMIC	2.638	Up-regulation
CMGC_MAPK_JNK_MAPK8_ST	P04637	TP53	P45983	MAPK8	T81	P85T	85	Missense	distal	4	no	7.682	7.658	EPSD;PhosphoSitePlus	COSMIC	2.638	Down-regulation
CMGC_MAPK_JNK_MAPK8_ST	P04637	TP53	P45983	MAPK8	T81	A74V	74	Missense	distal	-7	no	7.682	7.700	EPSD;PhosphoSitePlus	COSMIC	2.638	Up-regulation
CMGC_MAPK_JNK_MAPK8_ST	P04637	TP53	P45983	MAPK8	T81	P75S	75	Missense	distal	-6	no	7.682	7.593	EPSD;PhosphoSitePlus	COSMIC	2.638	Down-regulation
CMGC_MAPK_JNK_MAPK8_ST	P04637	TP53	P45983	MAPK8	T81	A76V	76	Missense	distal	-5	no	7.682	8.223	EPSD;PhosphoSitePlus	COSMIC	2.638	Up-regulation
CMGC_MAPK_JNK_MAPK8_ST	P04637	TP53	P45983	MAPK8	T81	P75R	75	Missense	distal	-6	no	7.682	7.748	EPSD;PhosphoSitePlus	COSMIC	2.638	Up-regulation
CMGC_MAPK_JNK_MAPK8_ST	P04637	TP53	P45983	MAPK8	T81	P87H	87	Missense	distal	6	no	7.682	7.659	EPSD;PhosphoSitePlus	COSMIC	2.638	Down-regulation
CMGC_MAPK_JNK_MAPK8_ST	P04637	TP53	P45983	MAPK8	T81	P87T	87	Missense	distal	6	no	7.682	7.704	EPSD;PhosphoSitePlus	COSMIC	2.638	Up-regulation
CMGC_MAPK_JNK_MAPK8_ST	P04637	TP53	P45983	MAPK8	T81	P87S	87	Missense	distal	6	no	7.682	7.707	EPSD;PhosphoSitePlus	COSMIC	2.638	Up-regulation
CMGC_MAPK_JNK_MAPK8_ST	P04637	TP53	P45983	MAPK8	T81	P87R	87	Missense	distal	6	no	7.682	7.647	EPSD;PhosphoSitePlus	COSMIC	2.638	Down-regulation
CMGC_MAPK_JNK_MAPK8_ST	P04637	TP53	P45983	MAPK8	T81	P87C	87	Missense	distal	6	no	7.682	7.658	EPSD;PhosphoSitePlus	COSMIC	2.638	Down-regulation
CMGC_MAPK_JNK_MAPK8_ST	P04637	TP53	P45983	MAPK8	T81	A86E	86	Missense	distal	5	no	7.682	7.663	EPSD;PhosphoSitePlus	COSMIC	2.638	Down-regulation
CMGC_MAPK_JNK_MAPK8_ST	P04637	TP53	P45983	MAPK8	T81	A86S	86	Missense	distal	5	no	7.682	7.674	EPSD;PhosphoSitePlus	COSMIC	2.638	Down-regulation
CMGC_MAPK_JNK_MAPK8_ST	P04637	TP53	P45983	MAPK8	T81	A83V	83	Missense	proximal	2	no	7.682	7.365	EPSD;PhosphoSitePlus	COSMIC	2.638	Down-regulation
CMGC_MAPK_JNK_MAPK8_ST	P04637	TP53	P45983	MAPK8	S127	C124W	124	Missense	distal	-3	no	8.358	8.222	EPSD	COSMIC	2.638	Down-regulation
CMGC_MAPK_JNK_MAPK8_ST	P04637	TP53	P45983	MAPK8	S127	C124F	124	Missense	distal	-3	no	8.358	8.239	EPSD	COSMIC	2.638	Down-regulation
CMGC_MAPK_JNK_MAPK8_ST	P04637	TP53	P45983	MAPK8	S127	C124S	124	Missense	distal	-3	no	8.358	8.613	EPSD	COSMIC	2.638	Up-regulation
CMGC_MAPK_JNK_MAPK8_ST	P04637	TP53	P45983	MAPK8	S127	S127A	127	Missense	central	0	yes	8.358	0.000	EPSD	COSMIC	2.638	Loss
CMGC_MAPK_JNK_MAPK8_ST	P04637	TP53	P45983	MAPK8	S127	S127L	127	Missense	central	0	yes	8.358	0.000	EPSD	COSMIC	2.638	Loss
CMGC_MAPK_JNK_MAPK8_ST	P04637	TP53	P45983	MAPK8	S127	C124T	124	Missense	distal	-3	no	8.358	8.594	EPSD	COSMIC	2.638	Up-regulation
CMGC_MAPK_JNK_MAPK8_ST	P04637	TP53	P45983	MAPK8	S127	S127I	127	Missense	central	0	yes	8.358	0.000	EPSD	COSMIC	2.638	Loss
CMGC_MAPK_JNK_MAPK8_ST	P04637	TP53	P45983	MAPK8	S127	S127G	127	Missense	central	0	yes	8.358	0.000	EPSD	COSMIC	2.638	Loss
CMGC_MAPK_JNK_MAPK8_ST	P04637	TP53	P45983	MAPK8	S127	N131H	131	Missense	distal	4	no	8.358	8.478	EPSD	COSMIC	2.638	Up-regulation
CMGC_MAPK_JNK_MAPK8_ST	P04637	TP53	P45983	MAPK8	S127	N131D	131	Missense	distal	4	no	8.358	8.604	EPSD	COSMIC	2.638	Up-regulation
CMGC_MAPK_JNK_MAPK8_ST	P04637	TP53	P45983	MAPK8	S127	T125I	125	Missense	proximal	-2	no	8.358	8.334	EPSD	COSMIC	2.638	Down-regulation
CMGC_MAPK_JNK_MAPK8_ST	P04637	TP53	P45983	MAPK8	S127	F134I	134	Missense	distal	7	no	8.358	8.323	EPSD	COSMIC	2.638	Down-regulation
CMGC_MAPK_JNK_MAPK8_ST	P04637	TP53	P45983	MAPK8	S127	K120T	120	Missense	distal	-7	no	8.358	8.363	EPSD	COSMIC	2.638	Up-regulation
CMGC_MAPK_JNK_MAPK8_ST	P04637	TP53	P45983	MAPK8	S127	F134S	134	Missense	distal	7	no	8.358	8.283	EPSD	COSMIC	2.638	Down-regulation
CMGC_MAPK_JNK_MAPK8_ST	P04637	TP53	P45983	MAPK8	S127	T125K	125	Missense	proximal	-2	no	8.358	8.363	EPSD	COSMIC	2.638	Up-regulation
CMGC_MAPK_JNK_MAPK8_ST	P04637	TP53	P45983	MAPK8	S127	M133I	133	Missense	distal	6	no	8.358	8.387	EPSD	COSMIC	2.638	Up-regulation
CMGC_MAPK_JNK_MAPK8_ST	P04637	TP53	P45983	MAPK8	S127	N131K	131	Missense	distal	4	no	8.358	8.836	EPSD	COSMIC;CCLE	2.638	Up-regulation
CMGC_MAPK_JNK_MAPK8_ST	P04637	TP53	P45983	MAPK8	S127	P128S	128	Missense	proximal	1	no	8.358	0.629	EPSD	COSMIC	2.638	Loss
CMGC_MAPK_JNK_MAPK8_ST	P04637	TP53	P45983	MAPK8	S127	M133L	133	Missense	distal	6	no	8.358	8.349	EPSD	COSMIC	2.638	Down-regulation
CMGC_MAPK_JNK_MAPK8_ST	P04637	TP53	P45983	MAPK8	S127	A129T	129	Missense	proximal	2	no	8.358	8.336	EPSD	COSMIC	2.638	Down-regulation
CMGC_MAPK_JNK_MAPK8_ST	P04637	TP53	P45983	MAPK8	S127	T123I	123	Missense	distal	-4	no	8.358	7.931	EPSD	COSMIC	2.638	Down-regulation
CMGC_MAPK_JNK_MAPK8_ST	P04637	TP53	P45983	MAPK8	S127	A129G	129	Missense	proximal	2	no	8.358	8.131	EPSD	COSMIC	2.638	Down-regulation
CMGC_MAPK_JNK_MAPK8_ST	P04637	TP53	P45983	MAPK8	S127	K132W	132	Missense	distal	5	no	8.358	8.471	EPSD	COSMIC	2.638	Up-regulation
CMGC_MAPK_JNK_MAPK8_ST	P04637	TP53	P45983	MAPK8	S127	A129V	129	Missense	proximal	2	no	8.358	8.040	EPSD	COSMIC	2.638	Down-regulation
CMGC_MAPK_JNK_MAPK8_ST	P04637	TP53	P45983	MAPK8	S127	P128A	128	Missense	proximal	1	no	8.358	2.010	EPSD	COSMIC	2.638	Loss
CMGC_MAPK_JNK_MAPK8_ST	P04637	TP53	P45983	MAPK8	S127	L130I	130	Missense	distal	3	no	8.358	8.254	EPSD	COSMIC	2.638	Down-regulation
CMGC_MAPK_JNK_MAPK8_ST	P04637	TP53	P45983	MAPK8	S127	S121F	121	Missense	distal	-6	no	8.358	8.538	EPSD	COSMIC	2.638	Up-regulation
CMGC_MAPK_JNK_MAPK8_ST	P04637	TP53	P45983	MAPK8	S127	A129D	129	Missense	proximal	2	no	8.358	8.197	EPSD	COSMIC	2.638	Down-regulation
CMGC_MAPK_JNK_MAPK8_ST	P04637	TP53	P45983	MAPK8	S127	K120Q	120	Missense	distal	-7	no	8.358	8.365	EPSD	COSMIC	2.638	Up-regulation
CMGC_MAPK_JNK_MAPK8_ST	P04637	TP53	P45983	MAPK8	S127	T125S	125	Missense	proximal	-2	no	8.358	8.332	EPSD	COSMIC	2.638	Down-regulation
CMGC_MAPK_JNK_MAPK8_ST	P04637	TP53	P45983	MAPK8	S127	P128L	128	Missense	proximal	1	no	8.358	0.785	EPSD	COSMIC	2.638	Loss
CMGC_MAPK_JNK_MAPK8_ST	P04637	TP53	P45983	MAPK8	S127	V122L	122	Missense	distal	-5	no	8.358	8.305	EPSD	COSMIC	2.638	Down-regulation
CMGC_MAPK_JNK_MAPK8_ST	P04637	TP53	P45983	MAPK8	S127	C124L	124	Missense	distal	-3	no	8.358	8.271	EPSD	COSMIC	2.638	Down-regulation
CMGC_MAPK_JNK_MAPK8_ST	P04637	TP53	P45983	MAPK8	S127	N131T	131	Missense	distal	4	no	8.358	8.757	EPSD	COSMIC	2.638	Up-regulation
CMGC_MAPK_JNK_MAPK8_ST	P04637	TP53	P45983	MAPK8	S127	M133V	133	Missense	distal	6	no	8.358	8.342	EPSD	COSMIC	2.638	Down-regulation
CMGC_MAPK_JNK_MAPK8_ST	P04637	TP53	P45983	MAPK8	T150	P151N	151	Missense	proximal	1	no	6.536	-1.828	EPSD	COSMIC	2.638	Loss
CMGC_MAPK_JNK_MAPK8_ST	P04637	TP53	P45983	MAPK8	T150	P152A	152	Missense	proximal	2	no	6.536	6.746	EPSD	COSMIC	2.638	Up-regulation
CMGC_MAPK_JNK_MAPK8_ST	P04637	TP53	P45983	MAPK8	T150	P152T	152	Missense	proximal	2	no	6.536	6.725	EPSD	COSMIC	2.638	Up-regulation
CMGC_MAPK_JNK_MAPK8_ST	P04637	TP53	P45983	MAPK8	T150	P152H	152	Missense	proximal	2	no	6.536	6.538	EPSD	COSMIC	2.638	Up-regulation
CMGC_MAPK_JNK_MAPK8_ST	P04637	TP53	P45983	MAPK8	T150	P153T	153	Missense	distal	3	no	6.536	6.439	EPSD	COSMIC	2.638	Down-regulation
CMGC_MAPK_JNK_MAPK8_ST	P04637	TP53	P45983	MAPK8	T150	V147I	147	Missense	distal	-3	no	6.536	6.771	EPSD	COSMIC	2.638	Up-regulation
CMGC_MAPK_JNK_MAPK8_ST	P04637	TP53	P45983	MAPK8	T150	P153L	153	Missense	distal	3	no	6.536	6.638	EPSD	COSMIC	2.638	Up-regulation
CMGC_MAPK_JNK_MAPK8_ST	P04637	TP53	P45983	MAPK8	T150	V147D	147	Missense	distal	-3	no	6.536	6.743	EPSD	COSMIC;GDSC;CCLE	2.638	Up-regulation
CMGC_MAPK_JNK_MAPK8_ST	P04637	TP53	P45983	MAPK8	T150	S149P	149	Missense	proximal	-1	no	6.536	6.526	EPSD	COSMIC	2.638	Down-regulation
CMGC_MAPK_JNK_MAPK8_ST	P04637	TP53	P45983	MAPK8	T150	P152K	152	Missense	proximal	2	no	6.536	6.803	EPSD	COSMIC	2.638	Up-regulation
CMGC_MAPK_JNK_MAPK8_ST	P04637	TP53	P45983	MAPK8	T150	P153S	153	Missense	distal	3	no	6.536	6.411	EPSD	COSMIC	2.638	Down-regulation
CMGC_MAPK_JNK_MAPK8_ST	P04637	TP53	P45983	MAPK8	T150	G154C	154	Missense	distal	4	no	6.536	6.549	EPSD	COSMIC	2.638	Up-regulation
CMGC_MAPK_JNK_MAPK8_ST	P04637	TP53	P45983	MAPK8	T150	S149F	149	Missense	proximal	-1	no	6.536	6.507	EPSD	COSMIC	2.638	Down-regulation
CMGC_MAPK_JNK_MAPK8_ST	P04637	TP53	P45983	MAPK8	T150	G154D	154	Missense	distal	4	no	6.536	6.678	EPSD	COSMIC	2.638	Up-regulation
CMGC_MAPK_JNK_MAPK8_ST	P04637	TP53	P45983	MAPK8	T150	V157I	157	Missense	distal	7	no	6.536	6.492	EPSD	COSMIC	2.638	Down-regulation
CMGC_MAPK_JNK_MAPK8_ST	P04637	TP53	P45983	MAPK8	T150	W146R	146	Missense	distal	-4	no	6.536	6.780	EPSD	COSMIC	2.638	Up-regulation
CMGC_MAPK_JNK_MAPK8_ST	P04637	TP53	P45983	MAPK8	T150	Q144R	144	Missense	distal	-6	no	6.536	6.638	EPSD	COSMIC	2.638	Up-regulation
CMGC_MAPK_JNK_MAPK8_ST	P04637	TP53	P45983	MAPK8	T150	D148V	148	Missense	proximal	-2	no	6.536	6.421	EPSD	COSMIC	2.638	Down-regulation
CMGC_MAPK_JNK_MAPK8_ST	P04637	TP53	P45983	MAPK8	T150	S149Y	149	Missense	proximal	-1	no	6.536	6.499	EPSD	COSMIC	2.638	Down-regulation
CMGC_MAPK_JNK_MAPK8_ST	P04637	TP53	P45983	MAPK8	T150	T150I	150	Missense	central	0	yes	6.536	0.000	EPSD	COSMIC	2.638	Loss
CMGC_MAPK_JNK_MAPK8_ST	P04637	TP53	P45983	MAPK8	T150	S149T	149	Missense	proximal	-1	no	6.536	6.537	EPSD	COSMIC	2.638	Up-regulation
CMGC_MAPK_JNK_MAPK8_ST	P04637	TP53	P45983	MAPK8	T150	W146G	146	Missense	distal	-4	no	6.536	6.693	EPSD	COSMIC	2.638	Up-regulation
CMGC_MAPK_JNK_MAPK8_ST	P04637	TP53	P45983	MAPK8	T150	L145M	145	Missense	distal	-5	no	6.536	6.505	EPSD	COSMIC	2.638	Down-regulation
CMGC_MAPK_JNK_MAPK8_ST	P04637	TP53	P45983	MAPK8	T150	V143L	143	Missense	distal	-7	no	6.536	6.535	EPSD	COSMIC	2.638	Down-regulation
CMGC_MAPK_JNK_MAPK8_ST	P04637	TP53	P45983	MAPK8	T150	R156S	156	Missense	distal	6	no	6.536	6.597	EPSD	COSMIC	2.638	Up-regulation
CMGC_MAPK_JNK_MAPK8_ST	P04637	TP53	P45983	MAPK8	T150	D148E	148	Missense	proximal	-2	no	6.536	6.590	EPSD	COSMIC	2.638	Up-regulation
CMGC_MAPK_JNK_MAPK8_ST	P04637	TP53	P45983	MAPK8	T150	V147F	147	Missense	distal	-3	no	6.536	6.556	EPSD	COSMIC	2.638	Up-regulation
CMGC_MAPK_JNK_MAPK8_ST	P04637	TP53	P45983	MAPK8	T150	T155A	155	Missense	distal	5	no	6.536	6.538	EPSD	COSMIC	2.638	Up-regulation
CMGC_MAPK_JNK_MAPK8_ST	P04637	TP53	P45983	MAPK8	T150	V147E	147	Missense	distal	-3	no	6.536	6.982	EPSD	COSMIC	2.638	Up-regulation
CMGC_MAPK_JNK_MAPK8_ST	P04637	TP53	P45983	MAPK8	T150	G154I	154	Missense	distal	4	no	6.536	6.691	EPSD	COSMIC	2.638	Up-regulation
CMGC_MAPK_JNK_MAPK8_ST	P04637	TP53	P45983	MAPK8	T150	D148G	148	Missense	proximal	-2	no	6.536	6.492	EPSD	COSMIC	2.638	Down-regulation
CMGC_MAPK_JNK_MAPK8_ST	P04637	TP53	P45983	MAPK8	T150	Q144K	144	Missense	distal	-6	no	6.536	6.471	EPSD	COSMIC	2.638	Down-regulation
CMGC_MAPK_JNK_MAPK8_ST	P04637	TP53	P45983	MAPK8	T150	V147A	147	Missense	distal	-3	no	6.536	6.966	EPSD	COSMIC	2.638	Up-regulation
CMGC_MAPK_JNK_MAPK8_ST	P04637	TP53	P45983	MAPK8	T150	L145V	145	Missense	distal	-5	no	6.536	6.589	EPSD	COSMIC	2.638	Up-regulation
CMGC_MAPK_JNK_MAPK8_ST	P04637	TP53	P45983	MAPK8	T150	T150K	150	Missense	central	0	yes	6.536	0.000	EPSD	COSMIC	2.638	Loss
CMGC_MAPK_JNK_MAPK8_ST	P04637	TP53	P45983	MAPK8	T150	P153H	153	Missense	distal	3	no	6.536	6.575	EPSD	COSMIC	2.638	Up-regulation
CMGC_MAPK_JNK_MAPK8_ST	P04637	TP53	P45983	MAPK8	T150	V157E	157	Missense	distal	7	no	6.536	6.452	EPSD	COSMIC	2.638	Down-regulation
CMGC_MAPK_JNK_MAPK8_ST	P04637	TP53	P45983	MAPK8	T150	T155S	155	Missense	distal	5	no	6.536	6.530	EPSD	COSMIC;CCLE	2.638	Down-regulation
CMGC_MAPK_JNK_MAPK8_ST	P04637	TP53	P45983	MAPK8	T150	D148H	148	Missense	proximal	-2	no	6.536	6.478	EPSD	COSMIC	2.638	Down-regulation
CMGC_MAPK_JNK_MAPK8_ST	P04637	TP53	P45983	MAPK8	T150	P153A	153	Missense	distal	3	no	6.536	6.429	EPSD	COSMIC	2.638	Down-regulation
CMGC_MAPK_JNK_MAPK8_ST	P04637	TP53	P45983	MAPK8	T150	T150R	150	Missense	central	0	yes	6.536	0.000	EPSD	COSMIC	2.638	Loss
CMGC_MAPK_JNK_MAPK8_ST	P04637	TP53	P45983	MAPK8	T150	T155L	155	Missense	distal	5	no	6.536	6.611	EPSD	COSMIC	2.638	Up-regulation
CMGC_MAPK_JNK_MAPK8_ST	P04637	TP53	P45983	MAPK8	T150	G154A	154	Missense	distal	4	no	6.536	6.879	EPSD	COSMIC	2.638	Up-regulation
CMGC_MAPK_JNK_MAPK8_ST	P04637	TP53	P45983	MAPK8	T150	T150A	150	Missense	central	0	yes	6.536	0.000	EPSD	COSMIC	2.638	Loss
CMGC_MAPK_JNK_MAPK8_ST	P04637	TP53	P45983	MAPK8	T150	W146C	146	Missense	distal	-4	no	6.536	6.813	EPSD	COSMIC	2.638	Up-regulation
CMGC_MAPK_JNK_MAPK8_ST	P04637	TP53	P45983	MAPK8	T150	P153F	153	Missense	distal	3	no	6.536	6.630	EPSD	COSMIC	2.638	Up-regulation
CMGC_MAPK_JNK_MAPK8_ST	P04637	TP53	P45983	MAPK8	T150	D148Y	148	Missense	proximal	-2	no	6.536	6.428	EPSD	COSMIC	2.638	Down-regulation
CMGC_MAPK_JNK_MAPK8_ST	P04637	TP53	P45983	MAPK8	T150	G154R	154	Missense	distal	4	no	6.536	6.515	EPSD	COSMIC	2.638	Down-regulation
CMGC_MAPK_JNK_MAPK8_ST	P04637	TP53	P45983	MAPK8	S183	G187V	187	Missense	distal	4	no	3.143	2.968	EPSD	COSMIC	2.638	Down-regulation
CMGC_MAPK_JNK_MAPK8_ST	P04637	TP53	P45983	MAPK8	S183	G187D	187	Missense	distal	4	no	3.143	3.285	EPSD	COSMIC	2.638	Up-regulation
CMGC_MAPK_JNK_MAPK8_ST	P04637	TP53	P45983	MAPK8	S183	G187A	187	Missense	distal	4	no	3.143	3.486	EPSD	COSMIC	2.638	Up-regulation
CMGC_MAPK_JNK_MAPK8_ST	P04637	TP53	P45983	MAPK8	S183	S183C	183	Missense	central	0	yes	3.143	0.000	EPSD	COSMIC	2.638	Loss
CMGC_MAPK_JNK_MAPK8_ST	P04637	TP53	P45983	MAPK8	S183	S183P	183	Missense	central	0	yes	3.143	0.000	EPSD	COSMIC	2.638	Loss
CMGC_MAPK_JNK_MAPK8_ST	P04637	TP53	P45983	MAPK8	S183	S185G	185	Missense	proximal	2	no	3.143	2.941	EPSD	COSMIC	2.638	Down-regulation
CMGC_MAPK_JNK_MAPK8_ST	P04637	TP53	P45983	MAPK8	S183	P190N	190	Missense	distal	7	no	3.143	3.174	EPSD	COSMIC	2.638	Up-regulation
CMGC_MAPK_JNK_MAPK8_ST	P04637	TP53	P45983	MAPK8	S183	D184N	184	Missense	proximal	1	no	3.143	1.085	EPSD	COSMIC	2.638	Loss
CMGC_MAPK_JNK_MAPK8_ST	P04637	TP53	P45983	MAPK8	S183	S185R	185	Missense	proximal	2	no	3.143	2.902	EPSD	COSMIC	2.638	Down-regulation
CMGC_MAPK_JNK_MAPK8_ST	P04637	TP53	P45983	MAPK8	S183	S183L	183	Missense	central	0	yes	3.143	0.000	EPSD	COSMIC	2.638	Loss
CMGC_MAPK_JNK_MAPK8_ST	P04637	TP53	P45983	MAPK8	S183	R181L	181	Missense	proximal	-2	no	3.143	3.134	EPSD	COSMIC	2.638	Down-regulation
CMGC_MAPK_JNK_MAPK8_ST	P04637	TP53	P45983	MAPK8	S183	H178P	178	Missense	distal	-5	no	3.143	2.947	EPSD	COSMIC	2.638	Down-regulation
CMGC_MAPK_JNK_MAPK8_ST	P04637	TP53	P45983	MAPK8	S183	D186N	186	Missense	distal	3	no	3.143	3.227	EPSD	COSMIC	2.638	Up-regulation
CMGC_MAPK_JNK_MAPK8_ST	P04637	TP53	P45983	MAPK8	S183	A189S	189	Missense	distal	6	no	3.143	3.147	EPSD	COSMIC	2.638	Up-regulation
CMGC_MAPK_JNK_MAPK8_ST	P04637	TP53	P45983	MAPK8	S183	H178L	178	Missense	distal	-5	no	3.143	3.307	EPSD	COSMIC	2.638	Up-regulation
CMGC_MAPK_JNK_MAPK8_ST	P04637	TP53	P45983	MAPK8	S183	D184Y	184	Missense	proximal	1	no	3.143	2.803	EPSD	COSMIC	2.638	Down-regulation
CMGC_MAPK_JNK_MAPK8_ST	P04637	TP53	P45983	MAPK8	S183	A189V	189	Missense	distal	6	no	3.143	3.068	EPSD	COSMIC	2.638	Down-regulation
CMGC_MAPK_JNK_MAPK8_ST	P04637	TP53	P45983	MAPK8	S183	H178Y	178	Missense	distal	-5	no	3.143	3.435	EPSD	COSMIC	2.638	Up-regulation
CMGC_MAPK_JNK_MAPK8_ST	P04637	TP53	P45983	MAPK8	S183	D186E	186	Missense	distal	3	no	3.143	3.036	EPSD	COSMIC	2.638	Down-regulation
CMGC_MAPK_JNK_MAPK8_ST	P04637	TP53	P45983	MAPK8	S183	C182Y	182	Missense	proximal	-1	no	3.143	3.125	EPSD	COSMIC	2.638	Down-regulation
CMGC_MAPK_JNK_MAPK8_ST	P04637	TP53	P45983	MAPK8	S183	D186H	186	Missense	distal	3	no	3.143	3.187	EPSD	COSMIC	2.638	Up-regulation
CMGC_MAPK_JNK_MAPK8_ST	P04637	TP53	P45983	MAPK8	S183	L188Q	188	Missense	distal	5	no	3.143	3.082	EPSD	COSMIC	2.638	Down-regulation
CMGC_MAPK_JNK_MAPK8_ST	P04637	TP53	P45983	MAPK8	S183	H178N	178	Missense	distal	-5	no	3.143	3.266	EPSD	COSMIC	2.638	Up-regulation
CMGC_MAPK_JNK_MAPK8_ST	P04637	TP53	P45983	MAPK8	S183	G187R	187	Missense	distal	4	no	3.143	3.122	EPSD	COSMIC;GDSC	2.638	Down-regulation
CMGC_MAPK_JNK_MAPK8_ST	P04637	TP53	P45983	MAPK8	S183	C182S	182	Missense	proximal	-1	no	3.143	3.162	EPSD	COSMIC	2.638	Up-regulation
CMGC_MAPK_JNK_MAPK8_ST	P04637	TP53	P45983	MAPK8	S183	P190F	190	Missense	distal	7	no	3.143	3.180	EPSD	COSMIC	2.638	Up-regulation
CMGC_MAPK_JNK_MAPK8_ST	P04637	TP53	P45983	MAPK8	S183	G187C	187	Missense	distal	4	no	3.143	3.156	EPSD	COSMIC	2.638	Up-regulation
CMGC_MAPK_JNK_MAPK8_ST	P04637	TP53	P45983	MAPK8	S183	S185T	185	Missense	proximal	2	no	3.143	3.147	EPSD	COSMIC	2.638	Up-regulation
CMGC_MAPK_JNK_MAPK8_ST	P04637	TP53	P45983	MAPK8	S183	P190H	190	Missense	distal	7	no	3.143	3.158	EPSD	COSMIC	2.638	Up-regulation
CMGC_MAPK_JNK_MAPK8_ST	P04637	TP53	P45983	MAPK8	S183	S185N	185	Missense	proximal	2	no	3.143	2.882	EPSD	COSMIC	2.638	Down-regulation
CMGC_MAPK_JNK_MAPK8_ST	P04637	TP53	P45983	MAPK8	S183	D186G	186	Missense	distal	3	no	3.143	3.213	EPSD	COSMIC	2.638	Up-regulation
CMGC_MAPK_JNK_MAPK8_ST	P04637	TP53	P45983	MAPK8	S183	D186V	186	Missense	distal	3	no	3.143	3.269	EPSD	COSMIC	2.638	Up-regulation
CMGC_MAPK_JNK_MAPK8_ST	P04637	TP53	P45983	MAPK8	S183	P177I	177	Missense	distal	-6	no	3.143	3.148	EPSD	COSMIC	2.638	Up-regulation
CMGC_MAPK_JNK_MAPK8_ST	P04637	TP53	P45983	MAPK8	S183	P190A	190	Missense	distal	7	no	3.143	3.110	EPSD	COSMIC	2.638	Down-regulation
CMGC_MAPK_JNK_MAPK8_ST	P04637	TP53	P45983	MAPK8	S183	S185C	185	Missense	proximal	2	no	3.143	2.951	EPSD	COSMIC	2.638	Down-regulation
CMGC_MAPK_JNK_MAPK8_ST	P04637	TP53	P45983	MAPK8	S183	S185I	185	Missense	proximal	2	no	3.143	3.021	EPSD	COSMIC	2.638	Down-regulation
CMGC_MAPK_JNK_MAPK8_ST	P04637	TP53	P45983	MAPK8	S183	A189P	189	Missense	distal	6	no	3.143	3.122	EPSD	COSMIC	2.638	Down-regulation
CMGC_MAPK_JNK_MAPK8_ST	P04637	TP53	P45983	MAPK8	S183	E180Q	180	Missense	distal	-3	no	3.143	2.986	EPSD	COSMIC	2.638	Down-regulation
CMGC_MAPK_JNK_MAPK8_ST	P04637	TP53	P45983	MAPK8	S183	R181S	181	Missense	proximal	-2	no	3.143	3.221	EPSD	COSMIC	2.638	Up-regulation
CMGC_MAPK_JNK_MAPK8_ST	P04637	TP53	P45983	MAPK8	S183	C182R	182	Missense	proximal	-1	no	3.143	3.137	EPSD	COSMIC	2.638	Down-regulation
CMGC_MAPK_JNK_MAPK8_ST	P04637	TP53	P45983	MAPK8	S183	E180G	180	Missense	distal	-3	no	3.143	2.811	EPSD	COSMIC	2.638	Down-regulation
CMGC_MAPK_JNK_MAPK8_ST	P04637	TP53	P45983	MAPK8	S183	L188M	188	Missense	distal	5	no	3.143	3.134	EPSD	COSMIC	2.638	Down-regulation
CMGC_MAPK_JNK_MAPK8_ST	P04637	TP53	P45983	MAPK8	S183	P177F	177	Missense	distal	-6	no	3.143	3.235	EPSD	COSMIC	2.638	Up-regulation
CMGC_MAPK_JNK_MAPK8_ST	P04637	TP53	P45983	MAPK8	S183	D184E	184	Missense	proximal	1	no	3.143	1.136	EPSD	COSMIC	2.638	Loss
CMGC_MAPK_JNK_MAPK8_ST	P04637	TP53	P45983	MAPK8	S183	A189G	189	Missense	distal	6	no	3.143	3.090	EPSD	COSMIC	2.638	Down-regulation
CMGC_MAPK_JNK_MAPK8_ST	P04637	TP53	P45983	MAPK8	S183	R181G	181	Missense	proximal	-2	no	3.143	3.156	EPSD	COSMIC	2.638	Up-regulation
CMGC_MAPK_JNK_MAPK8_ST	P04637	TP53	P45983	MAPK8	S183	D186X	186	Missense	distal	3	no	3.143	3.183	EPSD	COSMIC	2.638	Up-regulation
CMGC_MAPK_JNK_MAPK8_ST	P04637	TP53	P45983	MAPK8	S183	R181Y	181	Missense	proximal	-2	no	3.143	3.093	EPSD	COSMIC	2.638	Down-regulation
CMGC_MAPK_JNK_MAPK8_ST	P04637	TP53	P45983	MAPK8	S183	D184G	184	Missense	proximal	1	no	3.143	2.511	EPSD	COSMIC	2.638	Loss
CMGC_MAPK_JNK_MAPK8_ST	P04637	TP53	P45983	MAPK8	S314	S315P	315	Missense	proximal	1	no	-1.604	6.124	EPSD	COSMIC	2.638	Gain
CMGC_MAPK_JNK_MAPK8_ST	P04637	TP53	P45983	MAPK8	S315	N310T	310	Missense	distal	-5	no	8.332	7.900	EPSD	COSMIC	2.638	Down-regulation
CMGC_MAPK_JNK_MAPK8_ST	P04637	TP53	P45983	MAPK8	S315	Q317R	317	Missense	proximal	2	no	8.332	8.157	EPSD	COSMIC	2.638	Down-regulation
CMGC_MAPK_JNK_MAPK8_ST	P04637	TP53	P45983	MAPK8	S315	P309S	309	Missense	distal	-6	no	8.332	8.243	EPSD	COSMIC;GDSC;CCLE	2.638	Down-regulation
CMGC_MAPK_JNK_MAPK8_ST	P04637	TP53	P45983	MAPK8	S315	K319E	319	Missense	distal	4	no	8.332	8.251	EPSD	COSMIC	2.638	Down-regulation
CMGC_MAPK_JNK_MAPK8_ST	P04637	TP53	P45983	MAPK8	S315	P322L	322	Missense	distal	7	no	8.332	8.371	EPSD	COSMIC	2.638	Up-regulation
CMGC_MAPK_JNK_MAPK8_ST	P04637	TP53	P45983	MAPK8	S315	K320N	320	Missense	distal	5	no	8.332	8.420	EPSD	COSMIC;GDSC;CCLE	2.638	Up-regulation
CMGC_MAPK_JNK_MAPK8_ST	P04637	TP53	P45983	MAPK8	S315	N310L	310	Missense	distal	-5	no	8.332	8.372	EPSD	COSMIC	2.638	Up-regulation
CMGC_MAPK_JNK_MAPK8_ST	P04637	TP53	P45983	MAPK8	S315	T312S	312	Missense	distal	-3	no	8.332	8.350	EPSD	COSMIC	2.638	Up-regulation
CMGC_MAPK_JNK_MAPK8_ST	P04637	TP53	P45983	MAPK8	S315	N311Y	311	Missense	distal	-4	no	8.332	7.972	EPSD	COSMIC	2.638	Down-regulation
CMGC_MAPK_JNK_MAPK8_ST	P04637	TP53	P45983	MAPK8	S315	P322R	322	Missense	distal	7	no	8.332	8.356	EPSD	COSMIC	2.638	Up-regulation
CMGC_MAPK_JNK_MAPK8_ST	P04637	TP53	P45983	MAPK8	S315	N311K	311	Missense	distal	-4	no	8.332	9.318	EPSD	COSMIC	2.638	Up-regulation
CMGC_MAPK_JNK_MAPK8_ST	P04637	TP53	P45983	MAPK8	S315	Q317K	317	Missense	proximal	2	no	8.332	8.480	EPSD	COSMIC	2.638	Up-regulation
CMGC_MAPK_JNK_MAPK8_ST	P04637	TP53	P45983	MAPK8	S315	S315P	315	Missense	central	0	yes	8.332	0.000	EPSD	COSMIC	2.638	Loss
CMGC_MAPK_JNK_MAPK8_ST	P04637	TP53	P45983	MAPK8	S315	N310H	310	Missense	distal	-5	no	8.332	8.209	EPSD	COSMIC	2.638	Down-regulation
CMGC_MAPK_JNK_MAPK8_ST	P04637	TP53	P45983	MAPK8	S315	S314C	314	Missense	proximal	-1	no	8.332	8.313	EPSD	COSMIC	2.638	Down-regulation
CMGC_MAPK_JNK_MAPK8_ST	P04637	TP53	P45983	MAPK8	S315	P318A	318	Missense	distal	3	no	8.332	8.224	EPSD	COSMIC	2.638	Down-regulation
CMGC_MAPK_JNK_MAPK8_ST	P04637	TP53	P45983	MAPK8	S315	P316L	316	Missense	proximal	1	no	8.332	0.759	EPSD	COSMIC	2.638	Loss
CMGC_MAPK_JNK_MAPK8_ST	P04637	TP53	P45983	MAPK8	S315	L308M	308	Missense	distal	-7	no	8.332	8.330	EPSD	COSMIC	2.638	Down-regulation
CMGC_MAPK_JNK_MAPK8_ST	P04637	TP53	P45983	MAPK8	S315	S313C	313	Missense	proximal	-2	no	8.332	8.267	EPSD	COSMIC	2.638	Down-regulation
CMGC_MAPK_JNK_MAPK8_ST	P04637	TP53	P45983	MAPK8	S315	N311H	311	Missense	distal	-4	no	8.332	8.462	EPSD	COSMIC	2.638	Up-regulation
CMGC_MAPK_JNK_MAPK8_ST	P04637	TP53	P45983	MAPK8	S315	L308V	308	Missense	distal	-7	no	8.332	8.333	EPSD	COSMIC	2.638	Up-regulation
CMGC_MAPK_JNK_MAPK8_ST	P04637	TP53	P45983	MAPK8	S315	S314F	314	Missense	proximal	-1	no	8.332	8.302	EPSD	COSMIC	2.638	Down-regulation
CMGC_MAPK_JNK_MAPK8_ST	P04637	TP53	P45983	MAPK8	S315	K319R	319	Missense	distal	4	no	8.332	7.937	EPSD	COSMIC	2.638	Down-regulation
CMGC_MAPK_JNK_MAPK8_ST	P04637	TP53	P45983	MAPK8	S315	T312A	312	Missense	distal	-3	no	8.332	8.385	EPSD	COSMIC	2.638	Up-regulation
CMGC_MAPK_JNK_MAPK8_ST	P04637	TP53	P45983	MAPK8	S315	N310D	310	Missense	distal	-5	no	8.332	8.125	EPSD	COSMIC	2.638	Down-regulation
CMGC_MAPK_JNK_MAPK8_ST	P04637	TP53	P45983	MAPK8	S315	N311D	311	Missense	distal	-4	no	8.332	8.639	EPSD	COSMIC	2.638	Up-regulation
CMGC_MAPK_JNK_MAPK8_ST	P04637	TP53	P45983	MAPK8	S315	P309R	309	Missense	distal	-6	no	8.332	8.398	EPSD	COSMIC	2.638	Up-regulation
CMGC_MAPK_JNK_MAPK8_ST	P04637	TP53	P45983	MAPK8	S315	S313N	313	Missense	proximal	-2	no	8.332	8.214	EPSD	COSMIC	2.638	Down-regulation
CMGC_MAPK_JNK_MAPK8_ST	P04637	TP53	P45983	MAPK8	S315	Q317P	317	Missense	proximal	2	no	8.332	8.213	EPSD	COSMIC	2.638	Down-regulation
CMGC_MAPK_JNK_MAPK8_ST	P04637	TP53	P45983	MAPK8	S315	P316S	316	Missense	proximal	1	no	8.332	0.603	EPSD	COSMIC	2.638	Loss
CMGC_MAPK_JNK_MAPK8_ST	P04637	TP53	P45983	MAPK8	S378	R379P	379	Missense	proximal	1	no	0.159	7.295	EPSD	COSMIC	2.638	Gain
CMGC_MAPK_JNK_MAPK8_ST	Q96FI4	NEIL1	P45983	MAPK8	S61	R57C	57	Missense	distal	-4	no	8.363	8.396	EPSD;PhosphoSitePlus	COSMIC;GDSC	2.638	Up-regulation
CMGC_MAPK_JNK_MAPK8_ST	Q96FI4	NEIL1	P45983	MAPK8	S61	P68L	68	Missense	distal	7	no	8.363	8.402	EPSD;PhosphoSitePlus	COSMIC	2.638	Up-regulation
CMGC_MAPK_JNK_MAPK8_ST	Q96FI4	NEIL1	P45983	MAPK8	S207	S207I	207	Missense	central	0	yes	9.638	0.000	PhosphoSitePlus;EPSD	COSMIC	2.638	Loss
CMGC_MAPK_JNK_MAPK8_ST	Q96FI4	NEIL1	P45983	MAPK8	S306	A302V	302	Missense	distal	-4	no	8.823	7.967	EPSD;PhosphoSitePlus	COSMIC	2.638	Down-regulation
CMGC_MAPK_JNK_MAPK8_ST	Q12904	AIMP1	P45983	MAPK8	T84	M91V	91	Missense	distal	7	no	5.861	5.878	EPSD	COSMIC	2.638	Up-regulation
CMGC_MAPK_JNK_MAPK8_ST	Q12904	AIMP1	P45983	MAPK8	T84	P79A	79	Missense	distal	-5	no	5.861	5.732	EPSD	COSMIC	2.638	Down-regulation
CMGC_MAPK_JNK_MAPK8_ST	Q12904	AIMP1	P45983	MAPK8	T84	P81L	81	Missense	distal	-3	no	5.861	5.682	EPSD	COSMIC	2.638	Down-regulation
CMGC_MAPK_JNK_MAPK8_ST	Q12904	AIMP1	P45983	MAPK8	T84	S90Y	90	Missense	distal	6	no	5.861	5.774	EPSD	COSMIC	2.638	Down-regulation
CMGC_MAPK_JNK_MAPK8_ST	Q12904	AIMP1	P45983	MAPK8	T84	N89S	89	Missense	distal	5	no	5.861	5.792	EPSD	COSMIC;CCLE	2.638	Down-regulation
CMGC_MAPK_JNK_MAPK8_ST	Q12904	AIMP1	P45983	MAPK8	S140	G143R	143	Missense	distal	3	no	3.249	3.242	PhosphoSitePlus	COSMIC	2.638	Down-regulation
CMGC_MAPK_JNK_MAPK8_ST	Q12904	AIMP1	P45983	MAPK8	S140	Q139K	139	Missense	proximal	-1	no	3.249	3.261	PhosphoSitePlus	COSMIC	2.638	Up-regulation
CMGC_MAPK_JNK_MAPK8_ST	Q12904	AIMP1	P45983	MAPK8	S140	A145V	145	Missense	distal	5	no	3.249	3.322	PhosphoSitePlus	COSMIC	2.638	Up-regulation
CMGC_MAPK_JNK_MAPK8_ST	Q12904	AIMP1	P45983	MAPK8	S232	M226I	226	Missense	distal	-6	no	7.749	7.678	EPSD	COSMIC	2.638	Down-regulation
CMGC_MAPK_JNK_MAPK8_ST	Q12904	AIMP1	P45983	MAPK8	S232	M228I	228	Missense	distal	-4	no	7.749	8.025	EPSD	COSMIC	2.638	Up-regulation
CMGC_MAPK_JNK_MAPK8_ST	Q12904	AIMP1	P45983	MAPK8	S232	I236S	236	Missense	distal	4	no	7.749	7.939	EPSD	COSMIC	2.638	Up-regulation
CMGC_MAPK_JNK_MAPK8_ST	P37231	PPARG	P45983	MAPK8	S112	V108A	108	Missense	distal	-4	no	8.805	9.660	PhosphoSitePlus	COSMIC	2.638	Up-regulation
CMGC_MAPK_JNK_MAPK8_ST	P37231	PPARG	P45983	MAPK8	S273	D271E	271	Missense	proximal	-2	no	7.718	7.771	EPSD	COSMIC	2.638	Up-regulation
CMGC_MAPK_JNK_MAPK8_ST	P29966	MARCKS	P45983	MAPK8	S118	A122T	122	Missense	distal	4	no	7.692	7.644	EPSD	COSMIC	2.638	Down-regulation
CMGC_MAPK_JNK_MAPK8_ST	P29966	MARCKS	P45983	MAPK8	S118	T120M	120	Missense	proximal	2	no	7.692	7.440	EPSD	COSMIC	2.638	Down-regulation
CMGC_MAPK_JNK_MAPK8_ST	P29966	MARCKS	P45983	MAPK8	S135	S131A	131	Missense	distal	-4	no	8.101	7.923	EPSD	COSMIC	2.638	Down-regulation
CMGC_MAPK_JNK_MAPK8_ST	P29966	MARCKS	P45983	MAPK8	S135	A142P	142	Missense	distal	7	no	8.101	8.134	EPSD	COSMIC	2.638	Up-regulation
CMGC_MAPK_JNK_MAPK8_ST	P29966	MARCKS	P45983	MAPK8	T143	A142P	142	Missense	proximal	-1	no	6.452	6.440	EPSD	COSMIC	2.638	Down-regulation
CMGC_MAPK_JNK_MAPK8_ST	P29966	MARCKS	P45983	MAPK8	S145	A142P	142	Missense	distal	-3	no	8.513	8.315	EPSD	COSMIC	2.638	Down-regulation
CMGC_MAPK_JNK_MAPK8_ST	Q8N6T7	SIRT6	P45983	MAPK8	S10	G8E	8	Missense	proximal	-2	no	8.835	8.933	PhosphoSitePlus	COSMIC	2.638	Up-regulation
CMGC_MAPK_JNK_MAPK8_ST	Q8N6T7	SIRT6	P45983	MAPK8	T294	P292L	292	Missense	proximal	-2	no	9.150	8.957	EPSD	COSMIC	2.638	Down-regulation
CMGC_MAPK_JNK_MAPK8_ST	Q8N6T7	SIRT6	P45983	MAPK8	S303	R306P	306	Missense	distal	3	no	7.344	7.287	EPSD	COSMIC	2.638	Down-regulation
CMGC_MAPK_JNK_MAPK8_ST	Q8N6T7	SIRT6	P45983	MAPK8	S303	N308K	308	Missense	distal	5	no	7.344	7.256	EPSD	COSMIC	2.638	Down-regulation
CMGC_MAPK_JNK_MAPK8_ST	Q8N6T7	SIRT6	P45983	MAPK8	T305	R306P	306	Missense	proximal	1	no	0.139	7.275	EPSD	COSMIC	2.638	Gain
CMGC_MAPK_JNK_MAPK8_ST	Q8N6T7	SIRT6	P45983	MAPK8	S330	R333P	333	Missense	distal	3	no	9.096	9.039	EPSD	COSMIC	2.638	Down-regulation
CMGC_MAPK_JNK_MAPK8_ST	Q8N6T7	SIRT6	P45983	MAPK8	S338	R333P	333	Missense	distal	-5	no	9.406	9.114	EPSD	COSMIC	2.638	Down-regulation
CMGC_MAPK_JNK_MAPK8_ST	Q96LC9	BMF	P45983	MAPK8	T72	K68N	68	Missense	distal	-4	no	2.877	1.891	EPSD	COSMIC	2.638	Loss
CMGC_MAPK_JNK_MAPK8_ST	Q96LC9	BMF	P45983	MAPK8	S74	K68N	68	Missense	distal	-6	no	7.205	7.392	PhosphoSitePlus	COSMIC	2.638	Up-regulation
CMGC_MAPK_JNK_MAPK8_ST	Q7KZF4	SND1	P45983	MAPK8	T98	E100K	100	Missense	proximal	2	no	3.055	3.073	EPSD	COSMIC;CCLE	2.638	Up-regulation
CMGC_MAPK_JNK_MAPK8_ST	Q7KZF4	SND1	P45983	MAPK8	T98	T98A	98	Missense	central	0	yes	3.055	0.000	EPSD	COSMIC	2.638	Loss
CMGC_MAPK_JNK_MAPK8_ST	Q7KZF4	SND1	P45983	MAPK8	T98	V95A	95	Missense	distal	-3	no	3.055	3.484	EPSD	COSMIC	2.638	Up-regulation
CMGC_MAPK_JNK_MAPK8_ST	Q7KZF4	SND1	P45983	MAPK8	T103	E100K	100	Missense	distal	-3	no	8.214	8.240	PhosphoSitePlus	COSMIC;CCLE	2.638	Up-regulation
CMGC_MAPK_JNK_MAPK8_ST	Q7KZF4	SND1	P45983	MAPK8	T103	T98A	98	Missense	distal	-5	no	8.214	8.198	PhosphoSitePlus	COSMIC	2.638	Down-regulation
CMGC_MAPK_JNK_MAPK8_ST	Q7KZF4	SND1	P45983	MAPK8	T179	P183S	183	Missense	distal	4	no	3.146	3.171	EPSD	COSMIC	2.638	Up-regulation
CMGC_MAPK_JNK_MAPK8_ST	Q7KZF4	SND1	P45983	MAPK8	T240	G237D	237	Missense	distal	-3	no	7.851	7.945	EPSD	COSMIC	2.638	Up-regulation
CMGC_MAPK_JNK_MAPK8_ST	Q7KZF4	SND1	P45983	MAPK8	T240	A245S	245	Missense	distal	5	no	7.851	7.842	EPSD	COSMIC	2.638	Down-regulation
CMGC_MAPK_JNK_MAPK8_ST	Q7KZF4	SND1	P45983	MAPK8	S426	D420Y	420	Missense	distal	-6	no	9.196	9.335	EPSD	COSMIC	2.638	Up-regulation
CMGC_MAPK_JNK_MAPK8_ST	Q7KZF4	SND1	P45983	MAPK8	S426	E430K	430	Missense	distal	4	no	9.196	9.276	EPSD	COSMIC;GDSC;CCLE	2.638	Up-regulation
CMGC_MAPK_JNK_MAPK8_ST	Q7KZF4	SND1	P45983	MAPK8	S681	V685M	685	Missense	distal	4	no	3.232	3.341	EPSD	COSMIC;CCLE	2.638	Up-regulation
CMGC_MAPK_JNK_MAPK8_ST	Q7KZF4	SND1	P45983	MAPK8	S681	Y682C	682	Missense	proximal	1	no	3.232	2.299	EPSD	COSMIC;GDSC;CCLE	2.638	Loss
CMGC_MAPK_JNK_MAPK8_ST	Q7KZF4	SND1	P45983	MAPK8	S755	K752E	752	Missense	distal	-3	no	9.308	9.281	EPSD	COSMIC	2.638	Down-regulation
CMGC_MAPK_JNK_MAPK8_ST	Q7KZF4	SND1	P45983	MAPK8	S781	R776C	776	Missense	distal	-5	no	8.561	8.462	EPSD	COSMIC	2.638	Down-regulation
CMGC_MAPK_JNK_MAPK8_ST	P05787	KRT8	P45983	MAPK8	S13	S9F	9	Missense	distal	-4	no	2.739	1.801	EPSD	COSMIC	2.638	Loss
CMGC_MAPK_JNK_MAPK8_ST	P05787	KRT8	P45983	MAPK8	S74	S71R	71	Missense	distal	-3	no	7.728	7.423	PhosphoSitePlus;EPSD	COSMIC	2.638	Down-regulation
CMGC_MAPK_JNK_MAPK8_ST	P05787	KRT8	P45983	MAPK8	S74	S71I	71	Missense	distal	-3	no	7.728	7.569	PhosphoSitePlus;EPSD	COSMIC	2.638	Down-regulation
CMGC_MAPK_JNK_MAPK8_ST	P05787	KRT8	P45983	MAPK8	S74	V77G	77	Missense	distal	3	no	7.728	7.672	PhosphoSitePlus;EPSD	COSMIC	2.638	Down-regulation
CMGC_MAPK_JNK_MAPK8_ST	P05787	KRT8	P45983	MAPK8	S432	G434S	434	Missense	proximal	2	no	7.697	7.900	EPSD;PhosphoSitePlus	COSMIC	2.638	Up-regulation
CMGC_MAPK_JNK_MAPK8_ST	P11802	CDK4	P45983	MAPK8	S166	Q168E	168	Missense	proximal	2	no	3.246	3.376	EPSD	COSMIC	2.638	Up-regulation
CMGC_MAPK_JNK_MAPK8_ST	P11802	CDK4	P45983	MAPK8	S166	T172R	172	Missense	distal	6	no	3.246	3.189	EPSD	COSMIC	2.638	Down-regulation
CMGC_MAPK_JNK_MAPK8_ST	P11802	CDK4	P45983	MAPK8	S166	L161M	161	Missense	distal	-5	no	3.246	3.215	EPSD	COSMIC	2.638	Down-regulation
CMGC_MAPK_JNK_MAPK8_ST	P11802	CDK4	P45983	MAPK8	T172	V174M	174	Missense	proximal	2	no	6.276	6.321	PhosphoSitePlus	COSMIC	2.638	Up-regulation
CMGC_MAPK_JNK_MAPK8_ST	P11802	CDK4	P45983	MAPK8	T172	Q168E	168	Missense	distal	-4	no	6.276	6.413	PhosphoSitePlus	COSMIC	2.638	Up-regulation
CMGC_MAPK_JNK_MAPK8_ST	P11802	CDK4	P45983	MAPK8	T172	V174G	174	Missense	proximal	2	no	6.276	6.367	PhosphoSitePlus	COSMIC	2.638	Up-regulation
CMGC_MAPK_JNK_MAPK8_ST	P11802	CDK4	P45983	MAPK8	T172	T172R	172	Missense	central	0	yes	6.276	0.000	PhosphoSitePlus	COSMIC	2.638	Loss
CMGC_MAPK_JNK_MAPK8_ST	P11802	CDK4	P45983	MAPK8	T172	V175F	175	Missense	distal	3	no	6.276	6.249	PhosphoSitePlus	COSMIC	2.638	Down-regulation
CMGC_MAPK_JNK_MAPK8_ST	P11802	CDK4	P45983	MAPK8	S285	R288Q	288	Missense	distal	3	no	2.644	2.519	EPSD	COSMIC	2.638	Loss
CMGC_MAPK_JNK_MAPK8_ST	P11802	CDK4	P45983	MAPK8	S285	R283Q	283	Missense	proximal	-2	no	2.644	2.718	EPSD	COSMIC;GDSC;CCLE	2.638	Up-regulation
CMGC_MAPK_JNK_MAPK8_ST	P11802	CDK4	P45983	MAPK8	S285	A286T	286	Missense	proximal	1	no	2.644	2.005	EPSD	COSMIC	2.638	Loss
CMGC_MAPK_JNK_MAPK8_ST	P11802	CDK4	P45983	MAPK8	S285	S285C	285	Missense	central	0	yes	2.644	0.000	EPSD	COSMIC	2.638	Loss
CMGC_MAPK_JNK_MAPK8_ST	P11802	CDK4	P45983	MAPK8	S285	S285P	285	Missense	central	0	yes	2.644	0.000	EPSD	COSMIC	2.638	Loss
CMGC_MAPK_JNK_MAPK8_ST	P14618	PKM	P45983	MAPK8	S37	R32L	32	Missense	distal	-5	no	7.425	7.493	EPSD	COSMIC	2.638	Up-regulation
CMGC_MAPK_JNK_MAPK8_ST	P14618	PKM	P45983	MAPK8	T80	H81P	81	Missense	proximal	1	no	-1.012	6.903	EPSD	COSMIC	2.638	Gain
CMGC_MAPK_JNK_MAPK8_ST	P14618	PKM	P45983	MAPK8	S346	V348A	348	Missense	proximal	2	no	2.917	3.235	EPSD	COSMIC	2.638	Up-regulation
CMGC_MAPK_JNK_MAPK8_ST	P14618	PKM	P45983	MAPK8	S346	E344K	344	Missense	proximal	-2	no	2.917	2.915	EPSD	COSMIC	2.638	Down-regulation
CMGC_MAPK_JNK_MAPK8_ST	P14618	PKM	P45983	MAPK8	S346	S346F	346	Missense	central	0	yes	2.917	0.000	EPSD	COSMIC	2.638	Loss
CMGC_MAPK_JNK_MAPK8_ST	P14618	PKM	P45983	MAPK8	S406	P403T	403	Missense	distal	-3	no	4.057	4.201	EPSD	COSMIC	2.638	Up-regulation
CMGC_MAPK_JNK_MAPK8_ST	P14618	PKM	P45983	MAPK8	S406	D407N	407	Missense	proximal	1	no	4.057	1.998	EPSD	COSMIC	2.638	Loss
CMGC_MAPK_JNK_MAPK8_ST	P14618	PKM	P45983	MAPK8	S406	D407H	407	Missense	proximal	1	no	4.057	2.447	EPSD	COSMIC	2.638	Loss
CMGC_MAPK_JNK_MAPK8_ST	P14618	PKM	P45983	MAPK8	S406	R400H	400	Missense	distal	-6	no	4.057	4.035	EPSD	COSMIC	2.638	Down-regulation
CMGC_MAPK_JNK_MAPK8_ST	P14618	PKM	P45983	MAPK8	S406	A413T	413	Missense	distal	7	no	4.057	4.059	EPSD	COSMIC;GDSC;CCLE	2.638	Up-regulation
CMGC_MAPK_JNK_MAPK8_ST	P14618	PKM	P45983	MAPK8	S406	T409A	409	Missense	distal	3	no	4.057	4.048	EPSD	COSMIC	2.638	Down-regulation
CMGC_MAPK_JNK_MAPK8_ST	P14618	PKM	P45983	MAPK8	S437	T432M	432	Missense	distal	-5	no	2.254	2.695	EPSD	COSMIC	2.638	Gain
CMGC_MAPK_JNK_MAPK8_ST	O95644	NFATC1	P45983	MAPK8	S117	P113S	113	Missense	distal	-4	no	7.644	8.309	EPSD	COSMIC	2.638	Up-regulation
CMGC_MAPK_JNK_MAPK8_ST	O95644	NFATC1	P45983	MAPK8	S117	A112T	112	Missense	distal	-5	no	7.644	7.660	EPSD	COSMIC	2.638	Up-regulation
CMGC_MAPK_JNK_MAPK8_ST	O95644	NFATC1	P45983	MAPK8	S117	P118L	118	Missense	proximal	1	no	7.644	0.071	EPSD	COSMIC	2.638	Loss
CMGC_MAPK_JNK_MAPK8_ST	O95644	NFATC1	P45983	MAPK8	S151	K149R	149	Missense	proximal	-2	no	8.781	8.672	EPSD	COSMIC	2.638	Down-regulation
CMGC_MAPK_JNK_MAPK8_ST	O95644	NFATC1	P45983	MAPK8	S151	S153F	153	Missense	proximal	2	no	8.781	8.509	EPSD	COSMIC	2.638	Down-regulation
CMGC_MAPK_JNK_MAPK8_ST	O95644	NFATC1	P45983	MAPK8	S172	D167H	167	Missense	distal	-5	no	9.471	9.555	PhosphoSitePlus	COSMIC	2.638	Up-regulation
CMGC_MAPK_JNK_MAPK8_ST	O95644	NFATC1	P45983	MAPK8	S211	Q206H	206	Missense	distal	-5	no	8.735	8.955	EPSD	COSMIC	2.638	Up-regulation
CMGC_MAPK_JNK_MAPK8_ST	O95644	NFATC1	P45983	MAPK8	S211	T214I	214	Missense	distal	3	no	8.735	8.831	EPSD	COSMIC	2.638	Up-regulation
CMGC_MAPK_JNK_MAPK8_ST	O95644	NFATC1	P45983	MAPK8	S233	S237P	237	Missense	distal	4	no	8.750	8.725	EPSD	COSMIC	2.638	Down-regulation
CMGC_MAPK_JNK_MAPK8_ST	O95644	NFATC1	P45983	MAPK8	S233	C228Y	228	Missense	distal	-5	no	8.750	9.045	EPSD	COSMIC	2.638	Up-regulation
CMGC_MAPK_JNK_MAPK8_ST	O95644	NFATC1	P45983	MAPK8	S233	S233F	233	Missense	central	0	yes	8.750	0.000	EPSD	COSMIC	2.638	Loss
CMGC_MAPK_JNK_MAPK8_ST	O95644	NFATC1	P45983	MAPK8	S233	R235W	235	Missense	proximal	2	no	8.750	8.678	EPSD	COSMIC	2.638	Down-regulation
CMGC_MAPK_JNK_MAPK8_ST	O95644	NFATC1	P45983	MAPK8	S237	S237P	237	Missense	central	0	yes	9.190	0.000	EPSD	COSMIC	2.638	Loss
CMGC_MAPK_JNK_MAPK8_ST	O95644	NFATC1	P45983	MAPK8	S237	S233F	233	Missense	distal	-4	no	9.190	8.252	EPSD	COSMIC	2.638	Down-regulation
CMGC_MAPK_JNK_MAPK8_ST	O95644	NFATC1	P45983	MAPK8	S237	R235W	235	Missense	proximal	-2	no	9.190	9.196	EPSD	COSMIC	2.638	Up-regulation
CMGC_MAPK_JNK_MAPK8_ST	O95644	NFATC1	P45983	MAPK8	S241	S237P	237	Missense	distal	-4	no	9.684	9.019	EPSD	COSMIC	2.638	Down-regulation
CMGC_MAPK_JNK_MAPK8_ST	O95644	NFATC1	P45983	MAPK8	S241	R235W	235	Missense	distal	-6	no	9.684	9.710	EPSD	COSMIC	2.638	Up-regulation
CMGC_MAPK_JNK_MAPK8_ST	O95644	NFATC1	P45983	MAPK8	S261	S257F	257	Missense	distal	-4	no	9.415	8.477	EPSD	COSMIC	2.638	Down-regulation
CMGC_MAPK_JNK_MAPK8_ST	O95644	NFATC1	P45983	MAPK8	S261	R258I	258	Missense	distal	-3	no	9.415	9.561	EPSD	COSMIC	2.638	Up-regulation
CMGC_MAPK_JNK_MAPK8_ST	O95644	NFATC1	P45983	MAPK8	S261	R255K	255	Missense	distal	-6	no	9.415	9.249	EPSD	COSMIC	2.638	Down-regulation
CMGC_MAPK_JNK_MAPK8_ST	O95644	NFATC1	P45983	MAPK8	S278	T284M	284	Missense	distal	6	no	11.304	11.244	EPSD	COSMIC	2.638	Down-regulation
CMGC_MAPK_JNK_MAPK8_ST	O95644	NFATC1	P45983	MAPK8	S282	S286L	286	Missense	distal	4	no	9.467	9.035	EPSD	COSMIC;GDSC	2.638	Down-regulation
CMGC_MAPK_JNK_MAPK8_ST	O95644	NFATC1	P45983	MAPK8	S282	P287L	287	Missense	distal	5	no	9.467	9.466	EPSD	COSMIC	2.638	Down-regulation
CMGC_MAPK_JNK_MAPK8_ST	O95644	NFATC1	P45983	MAPK8	S282	T284M	284	Missense	proximal	2	no	9.467	9.216	EPSD	COSMIC	2.638	Down-regulation
CMGC_MAPK_JNK_MAPK8_ST	O95644	NFATC1	P45983	MAPK8	T284	S286L	286	Missense	proximal	2	no	7.545	7.283	EPSD	COSMIC;GDSC	2.638	Down-regulation
CMGC_MAPK_JNK_MAPK8_ST	O95644	NFATC1	P45983	MAPK8	T284	P287L	287	Missense	distal	3	no	7.545	7.647	EPSD	COSMIC	2.638	Up-regulation
CMGC_MAPK_JNK_MAPK8_ST	O95644	NFATC1	P45983	MAPK8	T284	T284M	284	Missense	central	0	yes	7.545	0.000	EPSD	COSMIC	2.638	Loss
CMGC_MAPK_JNK_MAPK8_ST	O95644	NFATC1	P45983	MAPK8	S286	S286L	286	Missense	central	0	yes	9.189	0.000	EPSD	COSMIC;GDSC	2.638	Loss
CMGC_MAPK_JNK_MAPK8_ST	O95644	NFATC1	P45983	MAPK8	S286	R292W	292	Missense	distal	6	no	9.189	9.180	EPSD	COSMIC	2.638	Down-regulation
CMGC_MAPK_JNK_MAPK8_ST	O95644	NFATC1	P45983	MAPK8	S286	P287L	287	Missense	proximal	1	no	9.189	1.617	EPSD	COSMIC	2.638	Loss
CMGC_MAPK_JNK_MAPK8_ST	O95644	NFATC1	P45983	MAPK8	S286	R292Q	292	Missense	distal	6	no	9.189	9.235	EPSD	COSMIC	2.638	Up-regulation
CMGC_MAPK_JNK_MAPK8_ST	O95644	NFATC1	P45983	MAPK8	S286	T284M	284	Missense	proximal	-2	no	9.189	9.073	EPSD	COSMIC	2.638	Down-regulation
CMGC_MAPK_JNK_MAPK8_ST	O95644	NFATC1	P45983	MAPK8	S290	S286L	286	Missense	distal	-4	no	8.101	7.109	EPSD	COSMIC;GDSC	2.638	Down-regulation
CMGC_MAPK_JNK_MAPK8_ST	O95644	NFATC1	P45983	MAPK8	S290	R292W	292	Missense	proximal	2	no	8.101	8.029	EPSD	COSMIC	2.638	Down-regulation
CMGC_MAPK_JNK_MAPK8_ST	O95644	NFATC1	P45983	MAPK8	S290	P287L	287	Missense	distal	-3	no	8.101	7.922	EPSD	COSMIC	2.638	Down-regulation
CMGC_MAPK_JNK_MAPK8_ST	O95644	NFATC1	P45983	MAPK8	S290	R292Q	292	Missense	proximal	2	no	8.101	8.275	EPSD	COSMIC	2.638	Up-regulation
CMGC_MAPK_JNK_MAPK8_ST	O95644	NFATC1	P45983	MAPK8	S290	T284M	284	Missense	distal	-6	no	8.101	8.240	EPSD	COSMIC	2.638	Up-regulation
CMGC_MAPK_JNK_MAPK8_ST	O95644	NFATC1	P45983	MAPK8	S359	D365N	365	Missense	distal	6	no	8.671	8.641	EPSD	COSMIC	2.638	Down-regulation
CMGC_MAPK_JNK_MAPK8_ST	O95644	NFATC1	P45983	MAPK8	S359	P363H	363	Missense	distal	4	no	8.671	8.369	EPSD	COSMIC	2.638	Down-regulation
CMGC_MAPK_JNK_MAPK8_ST	O95644	NFATC1	P45983	MAPK8	S403	W396G	396	Missense	distal	-7	no	8.267	8.263	EPSD	COSMIC	2.638	Down-regulation
CMGC_MAPK_JNK_MAPK8_ST	O95644	NFATC1	P45983	MAPK8	S403	P410L	410	Missense	distal	7	no	8.267	8.306	EPSD	COSMIC	2.638	Up-regulation
CMGC_MAPK_JNK_MAPK8_ST	O95644	NFATC1	P45983	MAPK8	S403	S406F	406	Missense	distal	3	no	8.267	8.486	EPSD	COSMIC;CCLE	2.638	Up-regulation
CMGC_MAPK_JNK_MAPK8_ST	O95644	NFATC1	P45983	MAPK8	S403	A397S	397	Missense	distal	-6	no	8.267	8.263	EPSD	COSMIC	2.638	Down-regulation
CMGC_MAPK_JNK_MAPK8_ST	O95644	NFATC1	P45983	MAPK8	S409	P410L	410	Missense	proximal	1	no	11.202	3.629	EPSD	COSMIC	2.638	Down-regulation
CMGC_MAPK_JNK_MAPK8_ST	O95644	NFATC1	P45983	MAPK8	S409	A414T	414	Missense	distal	5	no	11.202	11.200	EPSD	COSMIC	2.638	Down-regulation
CMGC_MAPK_JNK_MAPK8_ST	O95644	NFATC1	P45983	MAPK8	S409	S406F	406	Missense	distal	-3	no	11.202	10.828	EPSD	COSMIC;CCLE	2.638	Down-regulation
CMGC_MAPK_JNK_MAPK8_ST	O95644	NFATC1	P45983	MAPK8	S409	P413H	413	Missense	distal	4	no	11.202	10.899	EPSD	COSMIC;CCLE	2.638	Down-regulation
CMGC_MAPK_JNK_MAPK8_ST	O95644	NFATC1	P45983	MAPK8	T504	T505P	505	Missense	proximal	1	no	1.742	8.729	EPSD	COSMIC	2.638	Gain
CMGC_MAPK_JNK_MAPK8_ST	O95644	NFATC1	P45983	MAPK8	S542	I544T	544	Missense	proximal	2	no	3.642	3.768	EPSD	COSMIC	2.638	Up-regulation
CMGC_MAPK_JNK_MAPK8_ST	O95644	NFATC1	P45983	MAPK8	S542	E545Q	545	Missense	distal	3	no	3.642	3.686	EPSD	COSMIC	2.638	Up-regulation
CMGC_MAPK_JNK_MAPK8_ST	O95644	NFATC1	P45983	MAPK8	S542	R547Q	547	Missense	distal	5	no	3.642	3.591	EPSD	COSMIC	2.638	Down-regulation
CMGC_MAPK_JNK_MAPK8_ST	O95644	NFATC1	P45983	MAPK8	T706	P711L	711	Missense	distal	5	no	3.564	3.562	EPSD	COSMIC	2.638	Down-regulation
CMGC_MAPK_JNK_MAPK8_ST	O95644	NFATC1	P45983	MAPK8	T706	I701M	701	Missense	distal	-5	no	3.564	3.801	EPSD	COSMIC	2.638	Up-regulation
CMGC_MAPK_JNK_MAPK8_ST	O95644	NFATC1	P45983	MAPK8	T706	D708E	708	Missense	proximal	2	no	3.564	3.763	EPSD	COSMIC	2.638	Up-regulation
CMGC_MAPK_JNK_MAPK8_ST	O95644	NFATC1	P45983	MAPK8	S723	V718L	718	Missense	distal	-5	no	8.945	8.892	EPSD	COSMIC	2.638	Down-regulation
CMGC_MAPK_JNK_MAPK8_ST	O95644	NFATC1	P45983	MAPK8	S723	G716V	716	Missense	distal	-7	no	8.945	8.950	EPSD	COSMIC	2.638	Up-regulation
CMGC_MAPK_JNK_MAPK8_ST	O95644	NFATC1	P45983	MAPK8	S723	L725F	725	Missense	proximal	2	no	8.945	8.935	EPSD	COSMIC	2.638	Down-regulation
CMGC_MAPK_JNK_MAPK8_ST	O95644	NFATC1	P45983	MAPK8	S723	P724L	724	Missense	proximal	1	no	8.945	1.373	EPSD	COSMIC	2.638	Loss
CMGC_MAPK_JNK_MAPK8_ST	O95644	NFATC1	P45983	MAPK8	S723	R727K	727	Missense	distal	4	no	8.945	9.340	EPSD	COSMIC	2.638	Up-regulation
CMGC_MAPK_JNK_MAPK8_ST	O95644	NFATC1	P45983	MAPK8	S723	P717L	717	Missense	distal	-6	no	8.945	9.036	EPSD	COSMIC	2.638	Up-regulation
CMGC_MAPK_JNK_MAPK8_ST	O95644	NFATC1	P45983	MAPK8	S765	P762L	762	Missense	distal	-3	no	8.134	7.955	EPSD	COSMIC	2.638	Down-regulation
CMGC_MAPK_JNK_MAPK8_ST	O95644	NFATC1	P45983	MAPK8	S765	P762S	762	Missense	distal	-3	no	8.134	8.296	EPSD	COSMIC	2.638	Up-regulation
CMGC_MAPK_JNK_MAPK8_ST	O95644	NFATC1	P45983	MAPK8	S765	D770N	770	Missense	distal	5	no	8.134	8.156	EPSD	COSMIC	2.638	Up-regulation
CMGC_MAPK_JNK_MAPK8_ST	O95644	NFATC1	P45983	MAPK8	S765	A760T	760	Missense	distal	-5	no	8.134	8.150	EPSD	COSMIC	2.638	Up-regulation
CMGC_MAPK_JNK_MAPK8_ST	O95644	NFATC1	P45983	MAPK8	S765	D770Y	770	Missense	distal	5	no	8.134	8.194	EPSD	COSMIC	2.638	Up-regulation
CMGC_MAPK_JNK_MAPK8_ST	O95644	NFATC1	P45983	MAPK8	S765	V764M	764	Missense	proximal	-1	no	8.134	8.142	EPSD	COSMIC	2.638	Up-regulation
CMGC_MAPK_JNK_MAPK8_ST	O95644	NFATC1	P45983	MAPK8	S772	A775S	775	Missense	distal	3	no	5.824	5.805	EPSD	COSMIC	2.638	Down-regulation
CMGC_MAPK_JNK_MAPK8_ST	O95644	NFATC1	P45983	MAPK8	S772	D770N	770	Missense	proximal	-2	no	5.824	5.726	EPSD	COSMIC	2.638	Down-regulation
CMGC_MAPK_JNK_MAPK8_ST	O95644	NFATC1	P45983	MAPK8	S772	D770Y	770	Missense	proximal	-2	no	5.824	5.715	EPSD	COSMIC	2.638	Down-regulation
CMGC_MAPK_JNK_MAPK8_ST	O95644	NFATC1	P45983	MAPK8	S782	A781V	781	Missense	proximal	-1	no	6.523	6.487	EPSD	COSMIC	2.638	Down-regulation
CMGC_MAPK_JNK_MAPK8_ST	O95644	NFATC1	P45983	MAPK8	S782	A775S	775	Missense	distal	-7	no	6.523	6.522	EPSD	COSMIC	2.638	Down-regulation
CMGC_MAPK_JNK_MAPK8_ST	O95644	NFATC1	P45983	MAPK8	S813	P806L	806	Missense	distal	-7	no	9.277	9.288	EPSD	COSMIC	2.638	Up-regulation
CMGC_MAPK_JNK_MAPK8_ST	O95644	NFATC1	P45983	MAPK8	S813	P819L	819	Missense	distal	6	no	9.277	9.230	EPSD	COSMIC	2.638	Down-regulation
CMGC_MAPK_JNK_MAPK8_ST	O95644	NFATC1	P45983	MAPK8	S813	G815V	815	Missense	proximal	2	no	9.277	9.185	EPSD	COSMIC	2.638	Down-regulation
CMGC_MAPK_JNK_MAPK8_ST	O95644	NFATC1	P45983	MAPK8	S813	S813L	813	Missense	central	0	yes	9.277	0.000	EPSD	COSMIC	2.638	Loss
CMGC_MAPK_JNK_MAPK8_ST	O95644	NFATC1	P45983	MAPK8	S887	T881M	881	Missense	distal	-6	no	6.037	6.176	EPSD	COSMIC	2.638	Up-regulation
CMGC_MAPK_JNK_MAPK8_ST	O95644	NFATC1	P45983	MAPK8	S887	R893W	893	Missense	distal	6	no	6.037	6.027	EPSD	COSMIC	2.638	Down-regulation
CMGC_MAPK_JNK_MAPK8_ST	O95644	NFATC1	P45983	MAPK8	S887	R883H	883	Missense	distal	-4	no	6.037	6.095	EPSD	COSMIC	2.638	Up-regulation
CMGC_MAPK_JNK_MAPK8_ST	O95644	NFATC1	P45983	MAPK8	S887	A890V	890	Missense	distal	3	no	6.037	6.265	EPSD	COSMIC	2.638	Up-regulation
CMGC_MAPK_JNK_MAPK8_ST	O95644	NFATC1	P45983	MAPK8	S903	A907V	907	Missense	distal	4	no	8.141	7.623	EPSD	COSMIC	2.638	Down-regulation
CMGC_MAPK_JNK_MAPK8_ST	Q93045	STMN2	P45983	MAPK8	S62	E55D	55	Missense	distal	-7	no	8.093	8.102	EPSD	COSMIC	2.638	Up-regulation
CMGC_MAPK_JNK_MAPK8_ST	Q93045	STMN2	P45983	MAPK8	S62	S62Y	62	Missense	central	0	yes	8.093	0.000	EPSD	COSMIC	2.638	Loss
CMGC_MAPK_JNK_MAPK8_ST	Q93045	STMN2	P45983	MAPK8	S62	A67V	67	Missense	distal	5	no	8.093	8.166	EPSD	COSMIC	2.638	Up-regulation
CMGC_MAPK_JNK_MAPK8_ST	Q93045	STMN2	P45983	MAPK8	S73	K76Q	76	Missense	distal	3	no	7.616	7.713	PhosphoSitePlus	COSMIC	2.638	Up-regulation
CMGC_MAPK_JNK_MAPK8_ST	Q93045	STMN2	P45983	MAPK8	S73	A67V	67	Missense	distal	-6	no	7.616	7.817	PhosphoSitePlus	COSMIC	2.638	Up-regulation
CMGC_MAPK_JNK_MAPK8_ST	Q93045	STMN2	P45983	MAPK8	S73	L79R	79	Missense	distal	6	no	7.616	7.627	PhosphoSitePlus	COSMIC	2.638	Up-regulation
CMGC_MAPK_JNK_MAPK8_ST	Q93045	STMN2	P45983	MAPK8	S73	D78E	78	Missense	distal	5	no	7.616	7.558	PhosphoSitePlus	COSMIC	2.638	Down-regulation
CMGC_MAPK_JNK_MAPK8_ST	Q93045	STMN2	P45983	MAPK8	S73	L79M	79	Missense	distal	6	no	7.616	7.624	PhosphoSitePlus	COSMIC	2.638	Up-regulation
CMGC_MAPK_JNK_MAPK8_ST	Q93045	STMN2	P45983	MAPK8	S73	A72V	72	Missense	proximal	-1	no	7.616	7.580	PhosphoSitePlus	COSMIC	2.638	Down-regulation
CMGC_MAPK_JNK_MAPK8_ST	Q93045	STMN2	P45983	MAPK8	S73	S73Y	73	Missense	central	0	yes	7.616	0.000	PhosphoSitePlus	COSMIC	2.638	Loss
CMGC_MAPK_JNK_MAPK8_ST	Q96P20	NLRP3	P45983	MAPK8	S198	V200M	200	Missense	proximal	2	no	9.275	9.320	PhosphoSitePlus	COSMIC	2.638	Up-regulation
CMGC_MAPK_JNK_MAPK8_ST	Q96P20	NLRP3	P45983	MAPK8	S198	T195K	195	Missense	distal	-3	no	9.275	9.371	PhosphoSitePlus	COSMIC	2.638	Up-regulation
CMGC_MAPK_JNK_MAPK8_ST	Q96P20	NLRP3	P45983	MAPK8	S198	I203M	203	Missense	distal	5	no	9.275	9.299	PhosphoSitePlus	COSMIC	2.638	Up-regulation
CMGC_MAPK_JNK_MAPK8_ST	Q96P20	NLRP3	P45983	MAPK8	S387	R393G	393	Missense	distal	6	no	2.719	2.723	EPSD	COSMIC	2.638	Up-regulation
CMGC_MAPK_JNK_MAPK8_ST	Q96P20	NLRP3	P45983	MAPK8	S387	S387Y	387	Missense	central	0	yes	2.719	0.000	EPSD	COSMIC;GDSC;CCLE	2.638	Loss
CMGC_MAPK_JNK_MAPK8_ST	Q96P20	NLRP3	P45983	MAPK8	S387	Y385D	385	Missense	proximal	-2	no	2.719	2.828	EPSD	COSMIC;GDSC;CCLE	2.638	Up-regulation
CMGC_MAPK_JNK_MAPK8_ST	Q96P20	NLRP3	P45983	MAPK8	S387	E389K	389	Missense	proximal	2	no	2.719	2.737	EPSD	COSMIC	2.638	Up-regulation
CMGC_MAPK_JNK_MAPK8_ST	Q96P20	NLRP3	P45983	MAPK8	S387	E389V	389	Missense	proximal	2	no	2.719	2.363	EPSD	COSMIC;GDSC;CCLE	2.638	Loss
CMGC_MAPK_JNK_MAPK8_ST	Q96P20	NLRP3	P45983	MAPK8	S387	Y381H	381	Missense	distal	-6	no	2.719	2.621	EPSD	COSMIC	2.638	Loss
CMGC_MAPK_JNK_MAPK8_ST	P10275	AR	P45983	MAPK8	S83	Q79E	79	Missense	distal	-4	no	7.860	7.997	EPSD	COSMIC	2.638	Up-regulation
CMGC_MAPK_JNK_MAPK8_ST	P10275	AR	P45983	MAPK8	S83	Q86K	86	Missense	distal	3	no	7.860	7.763	EPSD	COSMIC	2.638	Down-regulation
CMGC_MAPK_JNK_MAPK8_ST	P10275	AR	P45983	MAPK8	S83	E81Q	81	Missense	proximal	-2	no	7.860	7.822	EPSD	COSMIC	2.638	Down-regulation
CMGC_MAPK_JNK_MAPK8_ST	P10275	AR	P45983	MAPK8	S83	Q90H	90	Missense	distal	7	no	7.860	7.895	EPSD	COSMIC	2.638	Up-regulation
CMGC_MAPK_JNK_MAPK8_ST	P10275	AR	P45983	MAPK8	S83	Q79R	79	Missense	distal	-4	no	7.860	7.339	EPSD	COSMIC	2.638	Down-regulation
CMGC_MAPK_JNK_MAPK8_ST	P10275	AR	P45983	MAPK8	S83	P84H	84	Missense	proximal	1	no	7.860	-0.056	EPSD	COSMIC	2.638	Loss
CMGC_MAPK_JNK_MAPK8_ST	P10275	AR	P45983	MAPK8	S96	S96Y	96	Missense	central	0	yes	7.626	0.000	EPSD	COSMIC	2.638	Loss
CMGC_MAPK_JNK_MAPK8_ST	P10275	AR	P45983	MAPK8	S96	Q90H	90	Missense	distal	-6	no	7.626	7.706	EPSD	COSMIC	2.638	Up-regulation
CMGC_MAPK_JNK_MAPK8_ST	P10275	AR	P45983	MAPK8	S96	S96F	96	Missense	central	0	yes	7.626	0.000	EPSD	COSMIC	2.638	Loss
CMGC_MAPK_JNK_MAPK8_ST	P10275	AR	P45983	MAPK8	S233	T229I	229	Missense	distal	-4	no	2.978	2.552	EPSD	COSMIC	2.638	Loss
CMGC_MAPK_JNK_MAPK8_ST	P10275	AR	P45983	MAPK8	S233	L226V	226	Missense	distal	-7	no	2.978	2.980	EPSD	COSMIC	2.638	Up-regulation
CMGC_MAPK_JNK_MAPK8_ST	P10275	AR	P45983	MAPK8	S233	N235K	235	Missense	proximal	2	no	2.978	3.321	EPSD	COSMIC	2.638	Up-regulation
CMGC_MAPK_JNK_MAPK8_ST	P10275	AR	P45983	MAPK8	S233	S233F	233	Missense	central	0	yes	2.978	0.000	EPSD	COSMIC	2.638	Loss
CMGC_MAPK_JNK_MAPK8_ST	P10275	AR	P45983	MAPK8	S233	T229C	229	Missense	distal	-4	no	2.978	2.425	EPSD	COSMIC	2.638	Loss
CMGC_MAPK_JNK_MAPK8_ST	P10275	AR	P45983	MAPK8	S258	L257P	257	Missense	proximal	-1	no	7.842	7.861	EPSD	COSMIC	2.638	Up-regulation
CMGC_MAPK_JNK_MAPK8_ST	P10275	AR	P45983	MAPK8	S258	R264Q	264	Missense	distal	6	no	7.842	7.888	EPSD	COSMIC	2.638	Up-regulation
CMGC_MAPK_JNK_MAPK8_ST	P10275	AR	P45983	MAPK8	S258	E252G	252	Missense	distal	-6	no	7.842	8.000	EPSD	COSMIC	2.638	Up-regulation
CMGC_MAPK_JNK_MAPK8_ST	P10275	AR	P45983	MAPK8	S258	E252K	252	Missense	distal	-6	no	7.842	7.837	EPSD	COSMIC	2.638	Down-regulation
CMGC_MAPK_JNK_MAPK8_ST	P10275	AR	P45983	MAPK8	S258	E255K	255	Missense	distal	-3	no	7.842	7.869	EPSD	COSMIC	2.638	Up-regulation
CMGC_MAPK_JNK_MAPK8_ST	P10275	AR	P45983	MAPK8	T282	E289G	289	Missense	distal	7	no	7.473	7.538	EPSD	COSMIC	2.638	Up-regulation
CMGC_MAPK_JNK_MAPK8_ST	P10275	AR	P45983	MAPK8	T282	P276S	276	Missense	distal	-6	no	7.473	7.384	EPSD	COSMIC	2.638	Down-regulation
CMGC_MAPK_JNK_MAPK8_ST	P10275	AR	P45983	MAPK8	T282	P283S	283	Missense	proximal	1	no	7.473	-0.256	EPSD	COSMIC	2.638	Loss
CMGC_MAPK_JNK_MAPK8_ST	P10275	AR	P45983	MAPK8	T282	A278T	278	Missense	distal	-4	no	7.473	7.436	EPSD	COSMIC	2.638	Down-regulation
CMGC_MAPK_JNK_MAPK8_ST	P10275	AR	P45983	MAPK8	T282	A285D	285	Missense	distal	3	no	7.473	7.575	EPSD	COSMIC	2.638	Up-regulation
CMGC_MAPK_JNK_MAPK8_ST	P10275	AR	P45983	MAPK8	T282	A278V	278	Missense	distal	-4	no	7.473	6.617	EPSD	COSMIC	2.638	Down-regulation
CMGC_MAPK_JNK_MAPK8_ST	P10275	AR	P45983	MAPK8	T282	A285V	285	Missense	distal	3	no	7.473	7.701	EPSD	COSMIC	2.638	Up-regulation
CMGC_MAPK_JNK_MAPK8_ST	P10275	AR	P45983	MAPK8	S302	G300D	300	Missense	proximal	-2	no	3.833	3.877	EPSD	COSMIC	2.638	Up-regulation
CMGC_MAPK_JNK_MAPK8_ST	P10275	AR	P45983	MAPK8	S302	D305N	305	Missense	distal	3	no	3.833	3.916	EPSD	COSMIC	2.638	Up-regulation
CMGC_MAPK_JNK_MAPK8_ST	P10275	AR	P45983	MAPK8	S302	S298R	298	Missense	distal	-4	no	3.833	3.031	EPSD	COSMIC	2.638	Down-regulation
CMGC_MAPK_JNK_MAPK8_ST	P10275	AR	P45983	MAPK8	S302	D297Y	297	Missense	distal	-5	no	3.833	4.208	EPSD	COSMIC	2.638	Up-regulation
CMGC_MAPK_JNK_MAPK8_ST	P10275	AR	P45983	MAPK8	S302	D296G	296	Missense	distal	-6	no	3.833	3.891	EPSD	COSMIC	2.638	Up-regulation
CMGC_MAPK_JNK_MAPK8_ST	P10275	AR	P45983	MAPK8	S302	E304K	304	Missense	proximal	2	no	3.833	3.851	EPSD	COSMIC	2.638	Up-regulation
CMGC_MAPK_JNK_MAPK8_ST	P10275	AR	P45983	MAPK8	S302	D296E	296	Missense	distal	-6	no	3.833	3.733	EPSD	COSMIC	2.638	Down-regulation
CMGC_MAPK_JNK_MAPK8_ST	P10275	AR	P45983	MAPK8	S302	T306I	306	Missense	distal	4	no	3.833	3.692	EPSD	COSMIC;GDSC;CCLE	2.638	Down-regulation
CMGC_MAPK_JNK_MAPK8_ST	P10275	AR	P45983	MAPK8	S310	D305N	305	Missense	distal	-5	no	10.471	10.678	EPSD	COSMIC	2.638	Up-regulation
CMGC_MAPK_JNK_MAPK8_ST	P10275	AR	P45983	MAPK8	S310	S310F	310	Missense	central	0	yes	10.471	0.000	EPSD	COSMIC	2.638	Loss
CMGC_MAPK_JNK_MAPK8_ST	P10275	AR	P45983	MAPK8	S310	E304K	304	Missense	distal	-6	no	10.471	10.466	EPSD	COSMIC	2.638	Down-regulation
CMGC_MAPK_JNK_MAPK8_ST	P10275	AR	P45983	MAPK8	S310	T306I	306	Missense	distal	-4	no	10.471	10.044	EPSD	COSMIC;GDSC;CCLE	2.638	Down-regulation
CMGC_MAPK_JNK_MAPK8_ST	P10275	AR	P45983	MAPK8	S310	F312L	312	Missense	proximal	2	no	10.471	10.480	EPSD	COSMIC	2.638	Up-regulation
CMGC_MAPK_JNK_MAPK8_ST	P10275	AR	P45983	MAPK8	S424	A420E	420	Missense	distal	-4	no	2.752	2.786	EPSD	COSMIC	2.638	Up-regulation
CMGC_MAPK_JNK_MAPK8_ST	P10275	AR	P45983	MAPK8	S424	G421V	421	Missense	distal	-3	no	2.752	2.639	EPSD	COSMIC	2.638	Down-regulation
CMGC_MAPK_JNK_MAPK8_ST	P10275	AR	P45983	MAPK8	S424	A430S	430	Missense	distal	6	no	2.752	2.755	EPSD	COSMIC	2.638	Up-regulation
CMGC_MAPK_JNK_MAPK8_ST	P10275	AR	P45983	MAPK8	S424	G421R	421	Missense	distal	-3	no	2.752	2.728	EPSD	COSMIC	2.638	Down-regulation
CMGC_MAPK_JNK_MAPK8_ST	P10275	AR	P45983	MAPK8	S424	A417E	417	Missense	distal	-7	no	2.752	2.751	EPSD	COSMIC	2.638	Down-regulation
CMGC_MAPK_JNK_MAPK8_ST	P10275	AR	P45983	MAPK8	S424	A417V	417	Missense	distal	-7	no	2.752	2.770	EPSD	COSMIC;CCLE	2.638	Up-regulation
CMGC_MAPK_JNK_MAPK8_ST	P10275	AR	P45983	MAPK8	S424	A417T	417	Missense	distal	-7	no	2.752	2.753	EPSD	COSMIC	2.638	Up-regulation
CMGC_MAPK_JNK_MAPK8_ST	P10275	AR	P45983	MAPK8	S424	S424C	424	Missense	central	0	yes	2.752	0.000	EPSD	COSMIC	2.638	Loss
CMGC_MAPK_JNK_MAPK8_ST	P10275	AR	P45983	MAPK8	S424	S424F	424	Missense	central	0	yes	2.752	0.000	EPSD	COSMIC	2.638	Loss
CMGC_MAPK_JNK_MAPK8_ST	P10275	AR	P45983	MAPK8	S426	A430T	430	Missense	distal	4	no	8.081	8.033	EPSD	COSMIC	2.638	Down-regulation
CMGC_MAPK_JNK_MAPK8_ST	P10275	AR	P45983	MAPK8	S426	A420E	420	Missense	distal	-6	no	8.081	8.071	EPSD	COSMIC	2.638	Down-regulation
CMGC_MAPK_JNK_MAPK8_ST	P10275	AR	P45983	MAPK8	S426	G421V	421	Missense	distal	-5	no	8.081	8.230	EPSD	COSMIC	2.638	Up-regulation
CMGC_MAPK_JNK_MAPK8_ST	P10275	AR	P45983	MAPK8	S426	A430S	430	Missense	distal	4	no	8.081	8.082	EPSD	COSMIC	2.638	Up-regulation
CMGC_MAPK_JNK_MAPK8_ST	P10275	AR	P45983	MAPK8	S426	G421R	421	Missense	distal	-5	no	8.081	8.109	EPSD	COSMIC	2.638	Up-regulation
CMGC_MAPK_JNK_MAPK8_ST	P10275	AR	P45983	MAPK8	S426	S433L	433	Missense	distal	7	no	8.081	8.159	EPSD	COSMIC	2.638	Up-regulation
CMGC_MAPK_JNK_MAPK8_ST	P10275	AR	P45983	MAPK8	S426	S424C	424	Missense	proximal	-2	no	8.081	8.017	EPSD	COSMIC	2.638	Down-regulation
CMGC_MAPK_JNK_MAPK8_ST	P10275	AR	P45983	MAPK8	S426	S424F	424	Missense	proximal	-2	no	8.081	7.966	EPSD	COSMIC	2.638	Down-regulation
CMGC_MAPK_JNK_MAPK8_ST	P10275	AR	P45983	MAPK8	S516	P515H	515	Missense	proximal	-1	no	7.555	7.545	EPSD	COSMIC	2.638	Down-regulation
CMGC_MAPK_JNK_MAPK8_ST	P10275	AR	P45983	MAPK8	S516	E523K	523	Missense	distal	7	no	7.555	7.540	EPSD	COSMIC	2.638	Down-regulation
CMGC_MAPK_JNK_MAPK8_ST	P10275	AR	P45983	MAPK8	S516	P515S	515	Missense	proximal	-1	no	7.555	7.565	EPSD	COSMIC	2.638	Up-regulation
CMGC_MAPK_JNK_MAPK8_ST	P10275	AR	P45983	MAPK8	S651	A646D	646	Missense	distal	-5	no	8.526	8.767	PhosphoSitePlus	COSMIC	2.638	Up-regulation
CMGC_MAPK_JNK_MAPK8_ST	P10275	AR	P45983	MAPK8	S651	S648R	648	Missense	distal	-3	no	8.526	8.221	PhosphoSitePlus	COSMIC	2.638	Down-regulation
CMGC_MAPK_JNK_MAPK8_ST	P10275	AR	P45983	MAPK8	S651	S648N	648	Missense	distal	-3	no	8.526	8.173	PhosphoSitePlus	COSMIC	2.638	Down-regulation
CMGC_MAPK_JNK_MAPK8_ST	P10275	AR	P45983	MAPK8	S651	E654K	654	Missense	distal	3	no	8.526	8.473	PhosphoSitePlus	COSMIC	2.638	Down-regulation
CMGC_MAPK_JNK_MAPK8_ST	P10275	AR	P45983	MAPK8	S651	S647F	647	Missense	distal	-4	no	8.526	7.588	PhosphoSitePlus	COSMIC	2.638	Down-regulation
CMGC_MAPK_JNK_MAPK8_ST	P10275	AR	P45983	MAPK8	S651	E655D	655	Missense	distal	4	no	8.526	8.375	PhosphoSitePlus	COSMIC	2.638	Down-regulation
CMGC_MAPK_JNK_MAPK8_ST	P35568	IRS1	P45983	MAPK8	S3	G9D	9	Missense	distal	6	no	8.521	8.544	EPSD	COSMIC	2.638	Up-regulation
CMGC_MAPK_JNK_MAPK8_ST	P35568	IRS1	P45983	MAPK8	S7	S11L	11	Missense	distal	4	no	3.222	2.790	EPSD	COSMIC	2.638	Down-regulation
CMGC_MAPK_JNK_MAPK8_ST	P35568	IRS1	P45983	MAPK8	S7	G9D	9	Missense	proximal	2	no	3.222	3.287	EPSD	COSMIC	2.638	Up-regulation
CMGC_MAPK_JNK_MAPK8_ST	P35568	IRS1	P45983	MAPK8	S273	S274P	274	Missense	proximal	1	no	2.152	9.881	EPSD	COSMIC	2.638	Gain
CMGC_MAPK_JNK_MAPK8_ST	P35568	IRS1	P45983	MAPK8	S307	R301C	301	Missense	distal	-6	no	4.798	4.773	EPSD	COSMIC	2.638	Down-regulation
CMGC_MAPK_JNK_MAPK8_ST	P35568	IRS1	P45983	MAPK8	S307	E306K	306	Missense	proximal	-1	no	4.798	4.801	EPSD	COSMIC	2.638	Up-regulation
CMGC_MAPK_JNK_MAPK8_ST	P35568	IRS1	P45983	MAPK8	S307	A310T	310	Missense	distal	3	no	4.798	4.808	EPSD	COSMIC	2.638	Up-regulation
CMGC_MAPK_JNK_MAPK8_ST	P35568	IRS1	P45983	MAPK8	S307	P313L	313	Missense	distal	6	no	4.798	4.751	EPSD	COSMIC;GDSC;CCLE	2.638	Down-regulation
CMGC_MAPK_JNK_MAPK8_ST	P35568	IRS1	P45983	MAPK8	S307	R302L	302	Missense	distal	-5	no	4.798	4.866	EPSD	COSMIC	2.638	Up-regulation
CMGC_MAPK_JNK_MAPK8_ST	P35568	IRS1	P45983	MAPK8	S307	I308M	308	Missense	proximal	1	no	4.798	2.812	EPSD	COSMIC	2.638	Down-regulation
CMGC_MAPK_JNK_MAPK8_ST	P35568	IRS1	P45983	MAPK8	S307	A310V	310	Missense	distal	3	no	4.798	5.026	EPSD	COSMIC	2.638	Up-regulation
CMGC_MAPK_JNK_MAPK8_ST	P35568	IRS1	P45983	MAPK8	T309	E306K	306	Missense	distal	-3	no	2.934	2.961	EPSD	COSMIC	2.638	Up-regulation
CMGC_MAPK_JNK_MAPK8_ST	P35568	IRS1	P45983	MAPK8	T309	A310T	310	Missense	proximal	1	no	2.934	2.295	EPSD	COSMIC	2.638	Loss
CMGC_MAPK_JNK_MAPK8_ST	P35568	IRS1	P45983	MAPK8	T309	P313L	313	Missense	distal	4	no	2.934	2.527	EPSD	COSMIC;GDSC;CCLE	2.638	Loss
CMGC_MAPK_JNK_MAPK8_ST	P35568	IRS1	P45983	MAPK8	T309	M316V	316	Missense	distal	7	no	2.934	2.951	EPSD	COSMIC	2.638	Up-regulation
CMGC_MAPK_JNK_MAPK8_ST	P35568	IRS1	P45983	MAPK8	T309	R302L	302	Missense	distal	-7	no	2.934	2.938	EPSD	COSMIC	2.638	Up-regulation
CMGC_MAPK_JNK_MAPK8_ST	P35568	IRS1	P45983	MAPK8	T309	M316I	316	Missense	distal	7	no	2.934	2.907	EPSD	COSMIC	2.638	Down-regulation
CMGC_MAPK_JNK_MAPK8_ST	P35568	IRS1	P45983	MAPK8	T309	I308M	308	Missense	proximal	-1	no	2.934	2.920	EPSD	COSMIC	2.638	Down-regulation
CMGC_MAPK_JNK_MAPK8_ST	P35568	IRS1	P45983	MAPK8	T309	A310V	310	Missense	proximal	1	no	2.934	0.537	EPSD	COSMIC	2.638	Loss
CMGC_MAPK_JNK_MAPK8_ST	P35568	IRS1	P45983	MAPK8	S312	E306K	306	Missense	distal	-6	no	8.564	8.559	PhosphoSitePlus	COSMIC	2.638	Down-regulation
CMGC_MAPK_JNK_MAPK8_ST	P35568	IRS1	P45983	MAPK8	S312	A310T	310	Missense	proximal	-2	no	8.564	8.534	PhosphoSitePlus	COSMIC	2.638	Down-regulation
CMGC_MAPK_JNK_MAPK8_ST	P35568	IRS1	P45983	MAPK8	S312	P313L	313	Missense	proximal	1	no	8.564	0.992	PhosphoSitePlus	COSMIC;GDSC;CCLE	2.638	Loss
CMGC_MAPK_JNK_MAPK8_ST	P35568	IRS1	P45983	MAPK8	S312	M316V	316	Missense	distal	4	no	8.564	8.455	PhosphoSitePlus	COSMIC	2.638	Down-regulation
CMGC_MAPK_JNK_MAPK8_ST	P35568	IRS1	P45983	MAPK8	S312	M316I	316	Missense	distal	4	no	8.564	8.784	PhosphoSitePlus	COSMIC	2.638	Up-regulation
CMGC_MAPK_JNK_MAPK8_ST	P35568	IRS1	P45983	MAPK8	S312	I308M	308	Missense	distal	-4	no	8.564	8.288	PhosphoSitePlus	COSMIC	2.638	Down-regulation
CMGC_MAPK_JNK_MAPK8_ST	P35568	IRS1	P45983	MAPK8	S312	A310V	310	Missense	proximal	-2	no	8.564	8.373	PhosphoSitePlus	COSMIC	2.638	Down-regulation
CMGC_MAPK_JNK_MAPK8_ST	P35568	IRS1	P45983	MAPK8	S345	S341L	341	Missense	distal	-4	no	6.753	5.761	EPSD	COSMIC	2.638	Down-regulation
CMGC_MAPK_JNK_MAPK8_ST	P35568	IRS1	P45983	MAPK8	S345	N352D	352	Missense	distal	7	no	6.753	6.724	EPSD	COSMIC	2.638	Down-regulation
CMGC_MAPK_JNK_MAPK8_ST	P35568	IRS1	P45983	MAPK8	S345	P349L	349	Missense	distal	4	no	6.753	6.346	EPSD	COSMIC	2.638	Down-regulation
CMGC_MAPK_JNK_MAPK8_ST	P35568	IRS1	P45983	MAPK8	S345	P346S	346	Missense	proximal	1	no	6.753	-0.976	EPSD	COSMIC	2.638	Loss
CMGC_MAPK_JNK_MAPK8_ST	P35568	IRS1	P45983	MAPK8	S348	S341L	341	Missense	distal	-7	no	8.627	8.644	EPSD	COSMIC	2.638	Up-regulation
CMGC_MAPK_JNK_MAPK8_ST	P35568	IRS1	P45983	MAPK8	S348	N352D	352	Missense	distal	4	no	8.627	8.873	EPSD	COSMIC	2.638	Up-regulation
CMGC_MAPK_JNK_MAPK8_ST	P35568	IRS1	P45983	MAPK8	S348	P349L	349	Missense	proximal	1	no	8.627	1.055	EPSD	COSMIC	2.638	Loss
CMGC_MAPK_JNK_MAPK8_ST	P35568	IRS1	P45983	MAPK8	S348	P346S	346	Missense	proximal	-2	no	8.627	8.522	EPSD	COSMIC	2.638	Down-regulation
CMGC_MAPK_JNK_MAPK8_ST	P35568	IRS1	P45983	MAPK8	S383	A379P	379	Missense	distal	-4	no	7.254	6.767	EPSD	COSMIC	2.638	Down-regulation
CMGC_MAPK_JNK_MAPK8_ST	P35568	IRS1	P45983	MAPK8	S383	S383L	383	Missense	central	0	yes	7.254	0.000	EPSD	COSMIC	2.638	Loss
CMGC_MAPK_JNK_MAPK8_ST	P35568	IRS1	P45983	MAPK8	S383	R381L	381	Missense	proximal	-2	no	7.254	7.245	EPSD	COSMIC	2.638	Down-regulation
CMGC_MAPK_JNK_MAPK8_ST	P35568	IRS1	P45983	MAPK8	S383	S383W	383	Missense	central	0	yes	7.254	0.000	EPSD	COSMIC	2.638	Loss
CMGC_MAPK_JNK_MAPK8_ST	P35568	IRS1	P45983	MAPK8	S383	P384S	384	Missense	proximal	1	no	7.254	-0.474	EPSD	COSMIC	2.638	Loss
CMGC_MAPK_JNK_MAPK8_ST	P35568	IRS1	P45983	MAPK8	S383	S385L	385	Missense	proximal	2	no	7.254	6.993	EPSD	COSMIC	2.638	Down-regulation
CMGC_MAPK_JNK_MAPK8_ST	P35568	IRS1	P45983	MAPK8	S388	S383L	383	Missense	distal	-5	no	6.604	7.076	EPSD	COSMIC	2.638	Up-regulation
CMGC_MAPK_JNK_MAPK8_ST	P35568	IRS1	P45983	MAPK8	S388	R381L	381	Missense	distal	-7	no	6.604	6.608	EPSD	COSMIC	2.638	Up-regulation
CMGC_MAPK_JNK_MAPK8_ST	P35568	IRS1	P45983	MAPK8	S388	S383W	383	Missense	distal	-5	no	6.604	7.054	EPSD	COSMIC	2.638	Up-regulation
CMGC_MAPK_JNK_MAPK8_ST	P35568	IRS1	P45983	MAPK8	S388	S395I	395	Missense	distal	7	no	6.604	6.645	EPSD	COSMIC;GDSC;CCLE	2.638	Up-regulation
CMGC_MAPK_JNK_MAPK8_ST	P35568	IRS1	P45983	MAPK8	S388	P384S	384	Missense	distal	-4	no	6.604	7.269	EPSD	COSMIC	2.638	Up-regulation
CMGC_MAPK_JNK_MAPK8_ST	P35568	IRS1	P45983	MAPK8	S388	S385L	385	Missense	distal	-3	no	6.604	6.263	EPSD	COSMIC	2.638	Down-regulation
CMGC_MAPK_JNK_MAPK8_ST	P35568	IRS1	P45983	MAPK8	S413	S415L	415	Missense	proximal	2	no	3.042	2.780	EPSD	COSMIC	2.638	Down-regulation
CMGC_MAPK_JNK_MAPK8_ST	P35568	IRS1	P45983	MAPK8	S413	G418V	418	Missense	distal	5	no	3.042	3.055	EPSD	COSMIC;GDSC;CCLE	2.638	Up-regulation
CMGC_MAPK_JNK_MAPK8_ST	P35568	IRS1	P45983	MAPK8	S419	S415L	415	Missense	distal	-4	no	7.849	6.858	EPSD	COSMIC	2.638	Down-regulation
CMGC_MAPK_JNK_MAPK8_ST	P35568	IRS1	P45983	MAPK8	S419	G418V	418	Missense	proximal	-1	no	7.849	7.840	EPSD	COSMIC;GDSC;CCLE	2.638	Down-regulation
CMGC_MAPK_JNK_MAPK8_ST	P35568	IRS1	P45983	MAPK8	S419	D422N	422	Missense	distal	3	no	7.849	7.933	EPSD	COSMIC	2.638	Up-regulation
CMGC_MAPK_JNK_MAPK8_ST	P35568	IRS1	P45983	MAPK8	S419	G423C	423	Missense	distal	4	no	7.849	7.862	EPSD	COSMIC;GDSC;CCLE	2.638	Up-regulation
CMGC_MAPK_JNK_MAPK8_ST	P35568	IRS1	P45983	MAPK8	S419	G424C	424	Missense	distal	5	no	7.849	7.835	EPSD	COSMIC	2.638	Down-regulation
CMGC_MAPK_JNK_MAPK8_ST	P35568	IRS1	P45983	MAPK8	S421	S415L	415	Missense	distal	-6	no	2.747	2.927	EPSD	COSMIC	2.638	Up-regulation
CMGC_MAPK_JNK_MAPK8_ST	P35568	IRS1	P45983	MAPK8	S421	G418V	418	Missense	distal	-3	no	2.747	2.634	EPSD	COSMIC;GDSC;CCLE	2.638	Loss
CMGC_MAPK_JNK_MAPK8_ST	P35568	IRS1	P45983	MAPK8	S421	D422N	422	Missense	proximal	1	no	2.747	0.688	EPSD	COSMIC	2.638	Loss
CMGC_MAPK_JNK_MAPK8_ST	P35568	IRS1	P45983	MAPK8	S421	G423C	423	Missense	proximal	2	no	2.747	2.756	EPSD	COSMIC;GDSC;CCLE	2.638	Up-regulation
CMGC_MAPK_JNK_MAPK8_ST	P35568	IRS1	P45983	MAPK8	S421	G424C	424	Missense	distal	3	no	2.747	2.722	EPSD	COSMIC	2.638	Down-regulation
CMGC_MAPK_JNK_MAPK8_ST	P35568	IRS1	P45983	MAPK8	S434	P435L	435	Missense	proximal	1	no	6.144	-1.428	EPSD	COSMIC	2.638	Loss
CMGC_MAPK_JNK_MAPK8_ST	P35568	IRS1	P45983	MAPK8	S434	R439Q	439	Missense	distal	5	no	6.144	6.093	EPSD	COSMIC	2.638	Down-regulation
CMGC_MAPK_JNK_MAPK8_ST	P35568	IRS1	P45983	MAPK8	S434	S441Y	441	Missense	distal	7	no	6.144	6.238	EPSD	COSMIC	2.638	Up-regulation
CMGC_MAPK_JNK_MAPK8_ST	P35568	IRS1	P45983	MAPK8	S434	S434G	434	Missense	central	0	yes	6.144	0.000	EPSD	COSMIC	2.638	Loss
CMGC_MAPK_JNK_MAPK8_ST	P35568	IRS1	P45983	MAPK8	S434	S441F	441	Missense	distal	7	no	6.144	6.220	EPSD	COSMIC	2.638	Up-regulation
CMGC_MAPK_JNK_MAPK8_ST	P35568	IRS1	P45983	MAPK8	S434	P435F	435	Missense	proximal	1	no	6.144	-2.028	EPSD	COSMIC	2.638	Loss
CMGC_MAPK_JNK_MAPK8_ST	P35568	IRS1	P45983	MAPK8	T446	G451C	451	Missense	distal	5	no	6.626	6.612	EPSD	COSMIC	2.638	Down-regulation
CMGC_MAPK_JNK_MAPK8_ST	P35568	IRS1	P45983	MAPK8	T446	R439Q	439	Missense	distal	-7	no	6.626	6.617	EPSD	COSMIC	2.638	Down-regulation
CMGC_MAPK_JNK_MAPK8_ST	P35568	IRS1	P45983	MAPK8	T446	D448E	448	Missense	proximal	2	no	6.626	6.826	EPSD	COSMIC	2.638	Up-regulation
CMGC_MAPK_JNK_MAPK8_ST	P35568	IRS1	P45983	MAPK8	T446	S441Y	441	Missense	distal	-5	no	6.626	7.227	EPSD	COSMIC	2.638	Up-regulation
CMGC_MAPK_JNK_MAPK8_ST	P35568	IRS1	P45983	MAPK8	T446	T453I	453	Missense	distal	7	no	6.626	6.659	EPSD	COSMIC	2.638	Up-regulation
CMGC_MAPK_JNK_MAPK8_ST	P35568	IRS1	P45983	MAPK8	T446	S441F	441	Missense	distal	-5	no	6.626	7.095	EPSD	COSMIC	2.638	Up-regulation
CMGC_MAPK_JNK_MAPK8_ST	P35568	IRS1	P45983	MAPK8	T446	R443C	443	Missense	distal	-3	no	6.626	6.676	EPSD	COSMIC	2.638	Up-regulation
CMGC_MAPK_JNK_MAPK8_ST	P35568	IRS1	P45983	MAPK8	T446	P447L	447	Missense	proximal	1	no	6.626	-0.946	EPSD	COSMIC	2.638	Loss
CMGC_MAPK_JNK_MAPK8_ST	P35568	IRS1	P45983	MAPK8	T446	R443L	443	Missense	distal	-3	no	6.626	6.590	EPSD	COSMIC	2.638	Down-regulation
CMGC_MAPK_JNK_MAPK8_ST	P35568	IRS1	P45983	MAPK8	T446	S444I	444	Missense	proximal	-2	no	6.626	6.628	EPSD	COSMIC	2.638	Up-regulation
CMGC_MAPK_JNK_MAPK8_ST	P35568	IRS1	P45983	MAPK8	T446	S449P	449	Missense	distal	3	no	6.626	6.752	EPSD	COSMIC	2.638	Up-regulation
CMGC_MAPK_JNK_MAPK8_ST	P35568	IRS1	P45983	MAPK8	T453	G451C	451	Missense	proximal	-2	no	8.706	8.707	EPSD	COSMIC	2.638	Up-regulation
CMGC_MAPK_JNK_MAPK8_ST	P35568	IRS1	P45983	MAPK8	T453	E460K	460	Missense	distal	7	no	8.706	8.692	EPSD	COSMIC	2.638	Down-regulation
CMGC_MAPK_JNK_MAPK8_ST	P35568	IRS1	P45983	MAPK8	T453	G458A	458	Missense	distal	5	no	8.706	8.647	EPSD	COSMIC	2.638	Down-regulation
CMGC_MAPK_JNK_MAPK8_ST	P35568	IRS1	P45983	MAPK8	T453	D448E	448	Missense	distal	-5	no	8.706	8.464	EPSD	COSMIC	2.638	Down-regulation
CMGC_MAPK_JNK_MAPK8_ST	P35568	IRS1	P45983	MAPK8	T453	T453I	453	Missense	central	0	yes	8.706	0.000	EPSD	COSMIC	2.638	Loss
CMGC_MAPK_JNK_MAPK8_ST	P35568	IRS1	P45983	MAPK8	T453	P447L	447	Missense	distal	-6	no	8.706	8.798	EPSD	COSMIC	2.638	Up-regulation
CMGC_MAPK_JNK_MAPK8_ST	P35568	IRS1	P45983	MAPK8	T453	S449P	449	Missense	distal	-4	no	8.706	8.042	EPSD	COSMIC	2.638	Down-regulation
CMGC_MAPK_JNK_MAPK8_ST	P35568	IRS1	P45983	MAPK8	T495	T495A	495	Missense	central	0	yes	8.034	0.000	EPSD	COSMIC	2.638	Loss
CMGC_MAPK_JNK_MAPK8_ST	P35568	IRS1	P45983	MAPK8	T495	G489D	489	Missense	distal	-6	no	8.034	7.976	EPSD	COSMIC	2.638	Down-regulation
CMGC_MAPK_JNK_MAPK8_ST	P35568	IRS1	P45983	MAPK8	T495	G497E	497	Missense	proximal	2	no	8.034	8.300	EPSD	COSMIC	2.638	Up-regulation
CMGC_MAPK_JNK_MAPK8_ST	P35568	IRS1	P45983	MAPK8	T495	H492Y	492	Missense	distal	-3	no	8.034	7.818	EPSD	COSMIC	2.638	Down-regulation
CMGC_MAPK_JNK_MAPK8_ST	P35568	IRS1	P45983	MAPK8	S503	G497E	497	Missense	distal	-6	no	7.527	7.369	EPSD	COSMIC	2.638	Down-regulation
CMGC_MAPK_JNK_MAPK8_ST	P35568	IRS1	P45983	MAPK8	S531	T533I	533	Missense	proximal	2	no	9.776	9.650	EPSD	COSMIC	2.638	Down-regulation
CMGC_MAPK_JNK_MAPK8_ST	P35568	IRS1	P45983	MAPK8	S531	H536N	536	Missense	distal	5	no	9.776	9.794	EPSD	COSMIC	2.638	Up-regulation
CMGC_MAPK_JNK_MAPK8_ST	P35568	IRS1	P45983	MAPK8	S531	H526Y	526	Missense	distal	-5	no	9.776	10.067	EPSD	COSMIC	2.638	Up-regulation
CMGC_MAPK_JNK_MAPK8_ST	P35568	IRS1	P45983	MAPK8	S531	G529D	529	Missense	proximal	-2	no	9.776	9.820	EPSD	COSMIC	2.638	Up-regulation
CMGC_MAPK_JNK_MAPK8_ST	P35568	IRS1	P45983	MAPK8	S531	T535A	535	Missense	distal	4	no	9.776	9.824	EPSD	COSMIC	2.638	Up-regulation
CMGC_MAPK_JNK_MAPK8_ST	P35568	IRS1	P45983	MAPK8	S531	Q537R	537	Missense	distal	6	no	9.776	9.730	EPSD	COSMIC	2.638	Down-regulation
CMGC_MAPK_JNK_MAPK8_ST	P35568	IRS1	P45983	MAPK8	S547	M554T	554	Missense	distal	7	no	2.753	2.694	EPSD	COSMIC	2.638	Down-regulation
CMGC_MAPK_JNK_MAPK8_ST	P35568	IRS1	P45983	MAPK8	S547	Y551C	551	Missense	distal	4	no	2.753	2.948	EPSD	COSMIC	2.638	Up-regulation
CMGC_MAPK_JNK_MAPK8_ST	P35568	IRS1	P45983	MAPK8	S616	V622M	622	Missense	distal	6	no	7.615	7.630	EPSD	COSMIC	2.638	Up-regulation
CMGC_MAPK_JNK_MAPK8_ST	P35568	IRS1	P45983	MAPK8	S616	P614A	614	Missense	proximal	-2	no	7.615	7.565	EPSD	COSMIC;CCLE	2.638	Down-regulation
CMGC_MAPK_JNK_MAPK8_ST	P35568	IRS1	P45983	MAPK8	S636	V640I	640	Missense	distal	4	no	6.770	7.100	EPSD	COSMIC;GDSC;CCLE	2.638	Up-regulation
CMGC_MAPK_JNK_MAPK8_ST	P35568	IRS1	P45983	MAPK8	S636	G630E	630	Missense	distal	-6	no	6.770	6.612	EPSD	COSMIC	2.638	Down-regulation
CMGC_MAPK_JNK_MAPK8_ST	P35568	IRS1	P45983	MAPK8	S666	G661D	661	Missense	distal	-5	no	8.196	8.044	EPSD	COSMIC	2.638	Down-regulation
CMGC_MAPK_JNK_MAPK8_ST	P35568	IRS1	P45983	MAPK8	S666	G669S	669	Missense	distal	3	no	8.196	8.006	EPSD	COSMIC	2.638	Down-regulation
CMGC_MAPK_JNK_MAPK8_ST	P35568	IRS1	P45983	MAPK8	S666	M664I	664	Missense	proximal	-2	no	8.196	8.288	EPSD	COSMIC	2.638	Up-regulation
CMGC_MAPK_JNK_MAPK8_ST	P35568	IRS1	P45983	MAPK8	S672	G677D	677	Missense	distal	5	no	9.197	9.175	EPSD	COSMIC	2.638	Down-regulation
CMGC_MAPK_JNK_MAPK8_ST	P35568	IRS1	P45983	MAPK8	S672	G669S	669	Missense	distal	-3	no	9.197	9.478	EPSD	COSMIC	2.638	Up-regulation
CMGC_MAPK_JNK_MAPK8_ST	P35568	IRS1	P45983	MAPK8	S672	G677V	677	Missense	distal	5	no	9.197	9.210	EPSD	COSMIC	2.638	Up-regulation
CMGC_MAPK_JNK_MAPK8_ST	P35568	IRS1	P45983	MAPK8	S672	P679T	679	Missense	distal	7	no	9.197	9.166	EPSD	COSMIC	2.638	Down-regulation
CMGC_MAPK_JNK_MAPK8_ST	P35568	IRS1	P45983	MAPK8	S672	P679L	679	Missense	distal	7	no	9.197	9.236	EPSD	COSMIC	2.638	Up-regulation
CMGC_MAPK_JNK_MAPK8_ST	P35568	IRS1	P45983	MAPK8	S736	D731G	731	Missense	distal	-5	no	6.755	6.907	EPSD	COSMIC	2.638	Up-regulation
CMGC_MAPK_JNK_MAPK8_ST	P35568	IRS1	P45983	MAPK8	S736	V738G	738	Missense	proximal	2	no	6.755	6.847	EPSD	COSMIC	2.638	Up-regulation
CMGC_MAPK_JNK_MAPK8_ST	P35568	IRS1	P45983	MAPK8	S736	G739E	739	Missense	distal	3	no	6.755	6.578	EPSD	COSMIC	2.638	Down-regulation
CMGC_MAPK_JNK_MAPK8_ST	P35568	IRS1	P45983	MAPK8	S736	N734I	734	Missense	proximal	-2	no	6.755	6.875	EPSD	COSMIC	2.638	Up-regulation
CMGC_MAPK_JNK_MAPK8_ST	P35568	IRS1	P45983	MAPK8	S736	N734K	734	Missense	proximal	-2	no	6.755	6.904	EPSD	COSMIC	2.638	Up-regulation
CMGC_MAPK_JNK_MAPK8_ST	P35568	IRS1	P45983	MAPK8	S745	V738G	738	Missense	distal	-7	no	8.391	8.386	EPSD	COSMIC	2.638	Down-regulation
CMGC_MAPK_JNK_MAPK8_ST	P35568	IRS1	P45983	MAPK8	S745	G739E	739	Missense	distal	-6	no	8.391	8.233	EPSD	COSMIC	2.638	Down-regulation
CMGC_MAPK_JNK_MAPK8_ST	P35568	IRS1	P45983	MAPK8	S892	L885Q	885	Missense	distal	-7	no	9.443	9.429	EPSD	COSMIC	2.638	Down-regulation
CMGC_MAPK_JNK_MAPK8_ST	P35568	IRS1	P45983	MAPK8	S918	P912L	912	Missense	distal	-6	no	7.634	7.725	EPSD	COSMIC	2.638	Up-regulation
CMGC_MAPK_JNK_MAPK8_ST	P35568	IRS1	P45983	MAPK8	S918	V913L	913	Missense	distal	-5	no	7.634	7.581	EPSD	COSMIC	2.638	Down-regulation
CMGC_MAPK_JNK_MAPK8_ST	P35568	IRS1	P45983	MAPK8	S918	H916Y	916	Missense	proximal	-2	no	7.634	7.583	EPSD	COSMIC	2.638	Down-regulation
CMGC_MAPK_JNK_MAPK8_ST	P35568	IRS1	P45983	MAPK8	S918	G911D	911	Missense	distal	-7	no	7.634	7.629	EPSD	COSMIC	2.638	Down-regulation
CMGC_MAPK_JNK_MAPK8_ST	P35568	IRS1	P45983	MAPK8	S1005	S1011I	1011	Missense	distal	6	no	7.156	7.122	EPSD	COSMIC	2.638	Down-regulation
CMGC_MAPK_JNK_MAPK8_ST	P35568	IRS1	P45983	MAPK8	S1005	R998C	998	Missense	distal	-7	no	7.156	7.154	EPSD	COSMIC;GDSC;CCLE	2.638	Down-regulation
CMGC_MAPK_JNK_MAPK8_ST	P35568	IRS1	P45983	MAPK8	S1005	D1003H	1003	Missense	proximal	-2	no	7.156	7.098	EPSD	COSMIC	2.638	Down-regulation
CMGC_MAPK_JNK_MAPK8_ST	P35568	IRS1	P45983	MAPK8	S1005	P1009S	1009	Missense	distal	4	no	7.156	7.181	EPSD	COSMIC	2.638	Up-regulation
CMGC_MAPK_JNK_MAPK8_ST	P35568	IRS1	P45983	MAPK8	S1041	A1042T	1042	Missense	proximal	1	no	2.655	2.016	EPSD	COSMIC	2.638	Loss
CMGC_MAPK_JNK_MAPK8_ST	P35568	IRS1	P45983	MAPK8	S1041	S1043F	1043	Missense	proximal	2	no	2.655	2.384	EPSD	COSMIC	2.638	Loss
CMGC_MAPK_JNK_MAPK8_ST	P35568	IRS1	P45983	MAPK8	S1043	A1042T	1042	Missense	proximal	-1	no	8.796	8.795	EPSD	COSMIC	2.638	Down-regulation
CMGC_MAPK_JNK_MAPK8_ST	P35568	IRS1	P45983	MAPK8	S1043	A1050V	1050	Missense	distal	7	no	8.796	8.875	EPSD	COSMIC	2.638	Up-regulation
CMGC_MAPK_JNK_MAPK8_ST	P35568	IRS1	P45983	MAPK8	S1043	S1043F	1043	Missense	central	0	yes	8.796	0.000	EPSD	COSMIC	2.638	Loss
CMGC_MAPK_JNK_MAPK8_ST	P35568	IRS1	P45983	MAPK8	S1078	P1079S	1079	Missense	proximal	1	no	5.863	-1.865	EPSD	COSMIC	2.638	Loss
CMGC_MAPK_JNK_MAPK8_ST	P35568	IRS1	P45983	MAPK8	S1078	S1078I	1078	Missense	central	0	yes	5.863	0.000	EPSD	COSMIC	2.638	Loss
CMGC_MAPK_JNK_MAPK8_ST	P35568	IRS1	P45983	MAPK8	S1078	R1074L	1074	Missense	distal	-4	no	5.863	5.673	EPSD	COSMIC;CCLE	2.638	Down-regulation
CMGC_MAPK_JNK_MAPK8_ST	P35568	IRS1	P45983	MAPK8	S1078	R1074Q	1074	Missense	distal	-4	no	5.863	6.384	EPSD	COSMIC;GDSC	2.638	Up-regulation
CMGC_MAPK_JNK_MAPK8_ST	P35568	IRS1	P45983	MAPK8	S1078	R1081C	1081	Missense	distal	3	no	5.863	5.846	EPSD	COSMIC	2.638	Down-regulation
CMGC_MAPK_JNK_MAPK8_ST	P35568	IRS1	P45983	MAPK8	T1107	E1102K	1102	Missense	distal	-5	no	7.378	7.301	EPSD	COSMIC	2.638	Down-regulation
CMGC_MAPK_JNK_MAPK8_ST	P35568	IRS1	P45983	MAPK8	S1109	E1102K	1102	Missense	distal	-7	no	2.694	2.690	EPSD	COSMIC	2.638	Down-regulation
CMGC_MAPK_JNK_MAPK8_ST	P35568	IRS1	P45983	MAPK8	S1143	R1140C	1140	Missense	distal	-3	no	3.274	3.324	EPSD	COSMIC;CCLE	2.638	Up-regulation
CMGC_MAPK_JNK_MAPK8_ST	P35568	IRS1	P45983	MAPK8	T1196	P1202L	1202	Missense	distal	6	no	8.037	7.990	EPSD	COSMIC	2.638	Down-regulation
CMGC_MAPK_JNK_MAPK8_ST	P35568	IRS1	P45983	MAPK8	S1231	D1225Y	1225	Missense	distal	-6	no	3.402	3.541	EPSD	COSMIC	2.638	Up-regulation
CMGC_MAPK_JNK_MAPK8_ST	P35568	IRS1	P45983	MAPK8	S1231	Q1235P	1235	Missense	distal	4	no	3.402	3.508	EPSD	COSMIC	2.638	Up-regulation
CMGC_MAPK_JNK_MAPK8_ST	P35568	IRS1	P45983	MAPK8	S1231	A1228V	1228	Missense	distal	-3	no	3.402	2.973	EPSD	COSMIC	2.638	Down-regulation
CMGC_MAPK_JNK_MAPK8_ST	P35568	IRS1	P45983	MAPK8	S1231	E1224Q	1224	Missense	distal	-7	no	3.402	3.406	EPSD	COSMIC	2.638	Up-regulation
CMGC_MAPK_JNK_MAPK8_ST	P35568	IRS1	P45983	MAPK8	S1231	L1226V	1226	Missense	distal	-5	no	3.402	3.455	EPSD	COSMIC	2.638	Up-regulation
CMGC_MAPK_JNK_MAPK8_ST	Q15750	TAB1	P45983	MAPK8	S339	A343T	343	Missense	distal	4	no	3.196	3.148	EPSD	COSMIC	2.638	Down-regulation
CMGC_MAPK_JNK_MAPK8_ST	Q15750	TAB1	P45983	MAPK8	T376	M372I	372	Missense	distal	-4	no	7.461	7.737	EPSD	COSMIC	2.638	Up-regulation
CMGC_MAPK_JNK_MAPK8_ST	Q15750	TAB1	P45983	MAPK8	T376	S373G	373	Missense	distal	-3	no	7.461	7.180	EPSD	COSMIC	2.638	Down-regulation
CMGC_MAPK_JNK_MAPK8_ST	Q15750	TAB1	P45983	MAPK8	T376	E371K	371	Missense	distal	-5	no	7.461	7.384	EPSD	COSMIC	2.638	Down-regulation
CMGC_MAPK_JNK_MAPK8_ST	Q15750	TAB1	P45983	MAPK8	S378	M372I	372	Missense	distal	-6	no	9.001	8.930	EPSD	COSMIC	2.638	Down-regulation
CMGC_MAPK_JNK_MAPK8_ST	Q15750	TAB1	P45983	MAPK8	S378	S373G	373	Missense	distal	-5	no	9.001	9.377	EPSD	COSMIC	2.638	Up-regulation
CMGC_MAPK_JNK_MAPK8_ST	Q15750	TAB1	P45983	MAPK8	S378	E371K	371	Missense	distal	-7	no	9.001	8.997	EPSD	COSMIC	2.638	Down-regulation
CMGC_MAPK_JNK_MAPK8_ST	Q15750	TAB1	P45983	MAPK8	T431	T435I	435	Missense	distal	4	no	6.638	6.497	EPSD	COSMIC	2.638	Down-regulation
CMGC_MAPK_JNK_MAPK8_ST	Q15750	TAB1	P45983	MAPK8	T431	Q437K	437	Missense	distal	6	no	6.638	6.670	EPSD	COSMIC	2.638	Up-regulation
CMGC_MAPK_JNK_MAPK8_ST	Q15750	TAB1	P45983	MAPK8	S438	P439L	439	Missense	proximal	1	no	7.509	-0.063	PhosphoSitePlus	COSMIC	2.638	Loss
CMGC_MAPK_JNK_MAPK8_ST	Q15750	TAB1	P45983	MAPK8	S438	T435I	435	Missense	distal	-3	no	7.509	7.368	PhosphoSitePlus	COSMIC	2.638	Down-regulation
CMGC_MAPK_JNK_MAPK8_ST	Q15750	TAB1	P45983	MAPK8	S438	Q437K	437	Missense	proximal	-1	no	7.509	7.521	PhosphoSitePlus	COSMIC	2.638	Up-regulation
CMGC_MAPK_JNK_MAPK8_ST	P40763	STAT3	P45983	MAPK8	T236	D242Y	242	Missense	distal	6	no	3.826	3.774	EPSD	COSMIC	2.638	Down-regulation
CMGC_MAPK_JNK_MAPK8_ST	P40763	STAT3	P45983	MAPK8	T236	E238V	238	Missense	proximal	2	no	3.826	3.470	EPSD	COSMIC	2.638	Down-regulation
CMGC_MAPK_JNK_MAPK8_ST	P40763	STAT3	P45983	MAPK8	T236	T236M	236	Missense	central	0	yes	3.826	0.000	EPSD	COSMIC	2.638	Loss
CMGC_MAPK_JNK_MAPK8_ST	P40763	STAT3	P45983	MAPK8	T412	L413P	413	Missense	proximal	1	no	-1.735	5.837	EPSD	COSMIC	2.638	Gain
CMGC_MAPK_JNK_MAPK8_ST	P40763	STAT3	P45983	MAPK8	T714	I711L	711	Missense	distal	-3	no	8.025	7.843	EPSD	COSMIC	2.638	Down-regulation
CMGC_MAPK_JNK_MAPK8_ST	P40763	STAT3	P45983	MAPK8	T721	D723N	723	Missense	proximal	2	no	2.709	2.584	EPSD	COSMIC	2.638	Loss
CMGC_MAPK_JNK_MAPK8_ST	P40763	STAT3	P45983	MAPK8	S727	D723N	723	Missense	distal	-4	no	7.051	6.744	PhosphoSitePlus	COSMIC	2.638	Down-regulation
CMGC_MAPK_JNK_MAPK8_ST	P61978	HNRNPK	P45983	MAPK8	S116	L123P	123	Missense	distal	7	no	7.091	7.051	EPSD	COSMIC	2.638	Down-regulation
CMGC_MAPK_JNK_MAPK8_ST	P61978	HNRNPK	P45983	MAPK8	S116	T118A	118	Missense	proximal	2	no	7.091	7.112	EPSD	COSMIC	2.638	Up-regulation
CMGC_MAPK_JNK_MAPK8_ST	P61978	HNRNPK	P45983	MAPK8	S284	M283T	283	Missense	proximal	-1	no	7.902	7.929	EPSD	COSMIC	2.638	Up-regulation
CMGC_MAPK_JNK_MAPK8_ST	P63104	YWHAZ	P45983	MAPK8	S58	R55C	55	Missense	distal	-3	no	3.016	3.065	EPSD	COSMIC	2.638	Up-regulation
CMGC_MAPK_JNK_MAPK8_ST	P98177	FOXO4	P45983	MAPK8	S111	I110V	110	Missense	proximal	-1	no	2.676	2.655	EPSD	COSMIC	2.638	Down-regulation
CMGC_MAPK_JNK_MAPK8_ST	P98177	FOXO4	P45983	MAPK8	S111	S116N	116	Missense	distal	5	no	2.676	2.745	EPSD	COSMIC	2.638	Up-regulation
CMGC_MAPK_JNK_MAPK8_ST	P98177	FOXO4	P45983	MAPK8	S111	P118L	118	Missense	distal	7	no	2.676	2.716	EPSD	COSMIC	2.638	Up-regulation
CMGC_MAPK_JNK_MAPK8_ST	P98177	FOXO4	P45983	MAPK8	T227	P222Q	222	Missense	distal	-5	no	8.527	8.505	EPSD;PhosphoSitePlus	COSMIC	2.638	Down-regulation
CMGC_MAPK_JNK_MAPK8_ST	P98177	FOXO4	P45983	MAPK8	T227	G225D	225	Missense	proximal	-2	no	8.527	8.572	EPSD;PhosphoSitePlus	COSMIC	2.638	Up-regulation
CMGC_MAPK_JNK_MAPK8_ST	P98177	FOXO4	P45983	MAPK8	T227	A226S	226	Missense	proximal	-1	no	8.527	8.526	EPSD;PhosphoSitePlus	COSMIC	2.638	Down-regulation
CMGC_MAPK_JNK_MAPK8_ST	P98177	FOXO4	P45983	MAPK8	T227	G225S	225	Missense	proximal	-2	no	8.527	8.592	EPSD;PhosphoSitePlus	COSMIC	2.638	Up-regulation
CMGC_MAPK_JNK_MAPK8_ST	P98177	FOXO4	P45983	MAPK8	T227	P228T	228	Missense	proximal	1	no	8.527	1.541	EPSD;PhosphoSitePlus	COSMIC	2.638	Loss
CMGC_MAPK_JNK_MAPK8_ST	P98177	FOXO4	P45983	MAPK8	T227	P231H	231	Missense	distal	4	no	8.527	8.225	EPSD;PhosphoSitePlus	COSMIC	2.638	Down-regulation
CMGC_MAPK_JNK_MAPK8_ST	P98177	FOXO4	P45983	MAPK8	S230	G225D	225	Missense	distal	-5	no	7.842	7.690	EPSD;PhosphoSitePlus	COSMIC	2.638	Down-regulation
CMGC_MAPK_JNK_MAPK8_ST	P98177	FOXO4	P45983	MAPK8	S230	A226S	226	Missense	distal	-4	no	7.842	8.020	EPSD;PhosphoSitePlus	COSMIC	2.638	Up-regulation
CMGC_MAPK_JNK_MAPK8_ST	P98177	FOXO4	P45983	MAPK8	S230	G225S	225	Missense	distal	-5	no	7.842	7.466	EPSD;PhosphoSitePlus	COSMIC	2.638	Down-regulation
CMGC_MAPK_JNK_MAPK8_ST	P98177	FOXO4	P45983	MAPK8	S230	P228T	228	Missense	proximal	-2	no	7.842	7.762	EPSD;PhosphoSitePlus	COSMIC	2.638	Down-regulation
CMGC_MAPK_JNK_MAPK8_ST	P98177	FOXO4	P45983	MAPK8	S230	P231H	231	Missense	proximal	1	no	7.842	-0.073	EPSD;PhosphoSitePlus	COSMIC	2.638	Loss
CMGC_MAPK_JNK_MAPK8_ST	P98177	FOXO4	P45983	MAPK8	S272	T269N	269	Missense	distal	-3	no	8.739	8.405	EPSD	COSMIC	2.638	Down-regulation
CMGC_MAPK_JNK_MAPK8_ST	P98177	FOXO4	P45983	MAPK8	T455	A460S	460	Missense	distal	5	no	8.305	8.296	PhosphoSitePlus;EPSD	COSMIC	2.638	Down-regulation
CMGC_MAPK_JNK_MAPK8_ST	P31946	YWHAB	P45983	MAPK8	S60	R57G	57	Missense	distal	-3	no	3.202	3.225	EPSD	COSMIC;CCLE	2.638	Up-regulation
CMGC_MAPK_JNK_MAPK8_ST	P31946	YWHAB	P45983	MAPK8	S60	S60F	60	Missense	central	0	yes	3.202	0.000	EPSD	COSMIC	2.638	Loss
CMGC_MAPK_JNK_MAPK8_ST	P31946	YWHAB	P45983	MAPK8	S186	Y180F	180	Missense	distal	-6	no	9.350	9.299	PhosphoSitePlus	COSMIC	2.638	Down-regulation
CMGC_MAPK_JNK_MAPK8_ST	P31946	YWHAB	P45983	MAPK8	S186	Y181D	181	Missense	distal	-5	no	9.350	8.974	PhosphoSitePlus	COSMIC	2.638	Down-regulation
CMGC_MAPK_JNK_MAPK8_ST	Q9NZ72	STMN3	P45983	MAPK8	S6	K11N	11	Missense	distal	5	no	2.777	2.865	EPSD	COSMIC	2.638	Up-regulation
CMGC_MAPK_JNK_MAPK8_ST	Q9NZ72	STMN3	P45983	MAPK8	S6	S3I	3	Missense	distal	-3	no	2.777	2.617	EPSD	COSMIC	2.638	Loss
CMGC_MAPK_JNK_MAPK8_ST	Q9NZ72	STMN3	P45983	MAPK8	S60	D63H	63	Missense	distal	3	no	8.468	8.511	PhosphoSitePlus	COSMIC	2.638	Up-regulation
CMGC_MAPK_JNK_MAPK8_ST	Q9NZ72	STMN3	P45983	MAPK8	S60	D63N	63	Missense	distal	3	no	8.468	8.551	PhosphoSitePlus	COSMIC	2.638	Up-regulation
CMGC_MAPK_JNK_MAPK8_ST	Q9NZ72	STMN3	P45983	MAPK8	S60	D63E	63	Missense	distal	3	no	8.468	8.360	PhosphoSitePlus	COSMIC	2.638	Down-regulation
CMGC_MAPK_JNK_MAPK8_ST	Q9NZ72	STMN3	P45983	MAPK8	S60	E55K	55	Missense	distal	-5	no	8.468	8.391	PhosphoSitePlus	COSMIC	2.638	Down-regulation
CMGC_MAPK_JNK_MAPK8_ST	Q9NZ72	STMN3	P45983	MAPK8	S65	P69H	69	Missense	distal	4	no	8.449	8.146	EPSD	COSMIC;GDSC;CCLE	2.638	Down-regulation
CMGC_MAPK_JNK_MAPK8_ST	Q9NZ72	STMN3	P45983	MAPK8	S65	D63H	63	Missense	proximal	-2	no	8.449	8.391	EPSD	COSMIC	2.638	Down-regulation
CMGC_MAPK_JNK_MAPK8_ST	Q9NZ72	STMN3	P45983	MAPK8	S65	D63N	63	Missense	proximal	-2	no	8.449	8.351	EPSD	COSMIC	2.638	Down-regulation
CMGC_MAPK_JNK_MAPK8_ST	Q9NZ72	STMN3	P45983	MAPK8	S65	D63E	63	Missense	proximal	-2	no	8.449	8.502	EPSD	COSMIC	2.638	Up-regulation
CMGC_MAPK_JNK_MAPK8_ST	Q9NZ72	STMN3	P45983	MAPK8	S65	S72F	72	Missense	distal	7	no	8.449	8.524	EPSD	COSMIC	2.638	Up-regulation
CMGC_MAPK_JNK_MAPK8_ST	Q9NZ72	STMN3	P45983	MAPK8	S68	P69H	69	Missense	proximal	1	no	7.193	-0.723	EPSD	COSMIC;GDSC;CCLE	2.638	Loss
CMGC_MAPK_JNK_MAPK8_ST	Q9NZ72	STMN3	P45983	MAPK8	S68	D63H	63	Missense	distal	-5	no	7.193	7.277	EPSD	COSMIC	2.638	Up-regulation
CMGC_MAPK_JNK_MAPK8_ST	Q9NZ72	STMN3	P45983	MAPK8	S68	D63N	63	Missense	distal	-5	no	7.193	7.400	EPSD	COSMIC	2.638	Up-regulation
CMGC_MAPK_JNK_MAPK8_ST	Q9NZ72	STMN3	P45983	MAPK8	S68	D63E	63	Missense	distal	-5	no	7.193	6.950	EPSD	COSMIC	2.638	Down-regulation
CMGC_MAPK_JNK_MAPK8_ST	Q9NZ72	STMN3	P45983	MAPK8	S68	S72F	72	Missense	distal	4	no	7.193	6.734	EPSD	COSMIC	2.638	Down-regulation
CMGC_MAPK_JNK_MAPK8_ST	Q9NZ72	STMN3	P45983	MAPK8	S73	P69H	69	Missense	distal	-4	no	7.517	7.439	EPSD	COSMIC;GDSC;CCLE	2.638	Down-regulation
CMGC_MAPK_JNK_MAPK8_ST	Q9NZ72	STMN3	P45983	MAPK8	S73	S72F	72	Missense	proximal	-1	no	7.517	7.488	EPSD	COSMIC	2.638	Down-regulation
CMGC_MAPK_JNK_MAPK8_ST	Q14653	IRF3	P45983	MAPK8	S123	P124L	124	Missense	proximal	1	no	7.954	0.381	EPSD	COSMIC	2.638	Loss
CMGC_MAPK_JNK_MAPK8_ST	Q14653	IRF3	P45983	MAPK8	S173	Q169R	169	Missense	distal	-4	no	8.448	7.928	PhosphoSitePlus	COSMIC;CCLE	2.638	Down-regulation
CMGC_MAPK_JNK_MAPK8_ST	Q14653	IRF3	P45983	MAPK8	S173	P166S	166	Missense	distal	-7	no	8.448	8.442	PhosphoSitePlus	COSMIC	2.638	Down-regulation
CMGC_MAPK_JNK_MAPK8_ST	Q14653	IRF3	P45983	MAPK8	S339	G335E	335	Missense	distal	-4	no	6.909	7.654	EPSD	COSMIC	2.638	Up-regulation
CMGC_MAPK_JNK_MAPK8_ST	Q14653	IRF3	P45983	MAPK8	S339	R341C	341	Missense	proximal	2	no	6.909	6.958	EPSD	COSMIC	2.638	Up-regulation
CMGC_MAPK_JNK_MAPK8_ST	Q14653	IRF3	P45983	MAPK8	S339	G337A	337	Missense	proximal	-2	no	6.909	7.029	EPSD	COSMIC	2.638	Up-regulation
CMGC_MAPK_JNK_MAPK8_ST	Q14653	IRF3	P45983	MAPK8	S339	G335V	335	Missense	distal	-4	no	6.909	6.764	EPSD	COSMIC	2.638	Down-regulation
CMGC_MAPK_JNK_MAPK8_ST	P04150	NR3C1	P45983	MAPK8	T8	R11I	11	Missense	distal	3	no	8.138	8.079	EPSD	COSMIC;GDSC;CCLE	2.638	Down-regulation
CMGC_MAPK_JNK_MAPK8_ST	P04150	NR3C1	P45983	MAPK8	T8	P15L	15	Missense	distal	7	no	8.138	8.177	EPSD	COSMIC	2.638	Up-regulation
CMGC_MAPK_JNK_MAPK8_ST	P04150	NR3C1	P45983	MAPK8	S45	A49V	49	Missense	distal	4	no	8.217	7.699	EPSD	COSMIC	2.638	Down-regulation
CMGC_MAPK_JNK_MAPK8_ST	P04150	NR3C1	P45983	MAPK8	S203	T208A	208	Missense	distal	5	no	8.326	8.327	EPSD	COSMIC	2.638	Up-regulation
CMGC_MAPK_JNK_MAPK8_ST	P04150	NR3C1	P45983	MAPK8	S211	T208A	208	Missense	distal	-3	no	7.111	7.165	EPSD	COSMIC	2.638	Up-regulation
CMGC_MAPK_JNK_MAPK8_ST	P04150	NR3C1	P45983	MAPK8	S267	P268L	268	Missense	proximal	1	no	7.238	-0.334	EPSD	COSMIC	2.638	Loss
CMGC_MAPK_JNK_MAPK8_ST	P04150	NR3C1	P45983	MAPK8	T288	E285K	285	Missense	distal	-3	no	7.401	7.427	EPSD	COSMIC	2.638	Up-regulation
CMGC_MAPK_JNK_MAPK8_ST	P04150	NR3C1	P45983	MAPK8	S395	Y393H	393	Missense	proximal	-2	no	7.684	7.734	EPSD	COSMIC	2.638	Up-regulation
CMGC_MAPK_JNK_MAPK8_ST	P04150	NR3C1	P45983	MAPK8	S404	P405T	405	Missense	proximal	1	no	8.117	1.130	EPSD	COSMIC	2.638	Loss
CMGC_MAPK_JNK_MAPK8_ST	P04150	NR3C1	P45983	MAPK8	T411	G415V	415	Missense	distal	4	no	2.730	2.554	EPSD	COSMIC	2.638	Loss
CMGC_MAPK_JNK_MAPK8_ST	P04150	NR3C1	P45983	MAPK8	T411	P405T	405	Missense	distal	-6	no	2.730	2.666	EPSD	COSMIC	2.638	Down-regulation
CMGC_MAPK_JNK_MAPK8_ST	Q9NPI6	DCP1A	P45983	MAPK8	T289	T290A	290	Missense	proximal	1	no	2.163	2.802	EPSD	COSMIC	2.638	Gain
CMGC_MAPK_JNK_MAPK8_ST	Q9NPI6	DCP1A	P45983	MAPK8	T290	P291T	291	Missense	proximal	1	no	7.257	0.270	EPSD	COSMIC	2.638	Loss
CMGC_MAPK_JNK_MAPK8_ST	Q9NPI6	DCP1A	P45983	MAPK8	T290	T290A	290	Missense	central	0	yes	7.257	0.000	EPSD	COSMIC	2.638	Loss
CMGC_MAPK_JNK_MAPK8_ST	Q9NPI6	DCP1A	P45983	MAPK8	T295	P291T	291	Missense	distal	-4	no	5.896	6.347	EPSD	COSMIC	2.638	Up-regulation
CMGC_MAPK_JNK_MAPK8_ST	Q9NPI6	DCP1A	P45983	MAPK8	T295	T290A	290	Missense	distal	-5	no	5.896	5.880	EPSD	COSMIC	2.638	Down-regulation
CMGC_MAPK_JNK_MAPK8_ST	Q9NPI6	DCP1A	P45983	MAPK8	S315	P313Q	313	Missense	proximal	-2	no	8.015	7.905	PhosphoSitePlus	COSMIC	2.638	Down-regulation
CMGC_MAPK_JNK_MAPK8_ST	Q9NPI6	DCP1A	P45983	MAPK8	S315	P313L	313	Missense	proximal	-2	no	8.015	7.822	PhosphoSitePlus	COSMIC	2.638	Down-regulation
CMGC_MAPK_JNK_MAPK8_ST	Q9NPI6	DCP1A	P45983	MAPK8	S319	P313Q	313	Missense	distal	-6	no	7.701	7.665	EPSD	COSMIC	2.638	Down-regulation
CMGC_MAPK_JNK_MAPK8_ST	Q9NPI6	DCP1A	P45983	MAPK8	S319	P313L	313	Missense	distal	-6	no	7.701	7.792	EPSD	COSMIC	2.638	Up-regulation
CMGC_MAPK_JNK_MAPK8_ST	Q9NPI6	DCP1A	P45983	MAPK8	S353	N357T	357	Missense	distal	4	no	7.247	7.646	EPSD	COSMIC	2.638	Up-regulation
CMGC_MAPK_JNK_MAPK8_ST	Q9NPI6	DCP1A	P45983	MAPK8	S422	M417V	417	Missense	distal	-5	no	8.028	8.112	EPSD	COSMIC	2.638	Up-regulation
CMGC_MAPK_JNK_MAPK8_ST	Q9NPI6	DCP1A	P45983	MAPK8	S422	A424T	424	Missense	proximal	2	no	8.028	8.007	EPSD	COSMIC	2.638	Down-regulation
CMGC_MAPK_JNK_MAPK8_ST	Q9NPI6	DCP1A	P45983	MAPK8	S422	Q427H	427	Missense	distal	5	no	8.028	8.059	EPSD	COSMIC	2.638	Up-regulation
CMGC_MAPK_JNK_MAPK8_ST	Q9NPI6	DCP1A	P45983	MAPK8	T430	A424T	424	Missense	distal	-6	no	6.351	6.373	EPSD	COSMIC	2.638	Up-regulation
CMGC_MAPK_JNK_MAPK8_ST	Q9NPI6	DCP1A	P45983	MAPK8	T430	Q427H	427	Missense	distal	-3	no	6.351	6.189	EPSD	COSMIC	2.638	Down-regulation
CMGC_MAPK_JNK_MAPK8_ST	Q9NPI6	DCP1A	P45983	MAPK8	S523	E518D	518	Missense	distal	-5	no	7.835	8.078	EPSD	COSMIC	2.638	Up-regulation
CMGC_MAPK_JNK_MAPK8_ST	Q9NPI6	DCP1A	P45983	MAPK8	S525	E518D	518	Missense	distal	-7	no	6.620	6.629	EPSD	COSMIC	2.638	Up-regulation
CMGC_MAPK_JNK_MAPK8_ST	Q06481	APLP2	P45983	MAPK8	T736	E739D	739	Missense	distal	3	no	7.976	8.084	PhosphoSitePlus	COSMIC	2.638	Up-regulation
CMGC_MAPK_JNK_MAPK8_ST	Q06481	APLP2	P45983	MAPK8	T736	R740C	740	Missense	distal	4	no	7.976	8.010	PhosphoSitePlus	COSMIC	2.638	Up-regulation
CMGC_MAPK_JNK_MAPK8_ST	Q06481	APLP2	P45983	MAPK8	T736	P733S	733	Missense	distal	-3	no	7.976	8.138	PhosphoSitePlus	COSMIC	2.638	Up-regulation
CMGC_MAPK_JNK_MAPK8_ST	Q9H2B2	SYT4	P45983	MAPK8	S114	T108A	108	Missense	distal	-6	no	8.459	8.437	EPSD	COSMIC	2.638	Down-regulation
CMGC_MAPK_JNK_MAPK8_ST	Q9H2B2	SYT4	P45983	MAPK8	S114	D117N	117	Missense	distal	3	no	8.459	8.542	EPSD	COSMIC;GDSC	2.638	Up-regulation
CMGC_MAPK_JNK_MAPK8_ST	Q9H2B2	SYT4	P45983	MAPK8	S114	S116F	116	Missense	proximal	2	no	8.459	8.187	EPSD	COSMIC	2.638	Down-regulation
CMGC_MAPK_JNK_MAPK8_ST	Q9H2B2	SYT4	P45983	MAPK8	S114	P112L	112	Missense	proximal	-2	no	8.459	8.266	EPSD	COSMIC	2.638	Down-regulation
CMGC_MAPK_JNK_MAPK8_ST	Q9H2B2	SYT4	P45983	MAPK8	T122	E128K	128	Missense	distal	6	no	7.396	7.412	EPSD	COSMIC	2.638	Up-regulation
CMGC_MAPK_JNK_MAPK8_ST	Q9H2B2	SYT4	P45983	MAPK8	T122	D117N	117	Missense	distal	-5	no	7.396	7.603	EPSD	COSMIC;GDSC	2.638	Up-regulation
CMGC_MAPK_JNK_MAPK8_ST	Q9H2B2	SYT4	P45983	MAPK8	T122	G129V	129	Missense	distal	7	no	7.396	7.416	EPSD	COSMIC	2.638	Up-regulation
CMGC_MAPK_JNK_MAPK8_ST	Q9H2B2	SYT4	P45983	MAPK8	T122	F126L	126	Missense	distal	4	no	7.396	7.422	EPSD	COSMIC	2.638	Up-regulation
CMGC_MAPK_JNK_MAPK8_ST	Q9H2B2	SYT4	P45983	MAPK8	T122	S116F	116	Missense	distal	-6	no	7.396	7.577	EPSD	COSMIC	2.638	Up-regulation
CMGC_MAPK_JNK_MAPK8_ST	Q9H2B2	SYT4	P45983	MAPK8	T122	L127F	127	Missense	distal	5	no	7.396	7.390	EPSD	COSMIC	2.638	Down-regulation
CMGC_MAPK_JNK_MAPK8_ST	Q9H2B2	SYT4	P45983	MAPK8	S135	L139P	139	Missense	distal	4	no	9.420	9.826	PhosphoSitePlus	COSMIC	2.638	Up-regulation
CMGC_MAPK_JNK_MAPK8_ST	Q9H2B2	SYT4	P45983	MAPK8	S135	S142F	142	Missense	distal	7	no	9.420	9.495	PhosphoSitePlus	COSMIC	2.638	Up-regulation
CMGC_MAPK_JNK_MAPK8_ST	Q9H2B2	SYT4	P45983	MAPK8	S135	E128K	128	Missense	distal	-7	no	9.420	9.416	PhosphoSitePlus	COSMIC	2.638	Down-regulation
CMGC_MAPK_JNK_MAPK8_ST	Q9H2B2	SYT4	P45983	MAPK8	S135	G129V	129	Missense	distal	-6	no	9.420	9.473	PhosphoSitePlus	COSMIC	2.638	Up-regulation
CMGC_MAPK_JNK_MAPK8_ST	Q9H2B2	SYT4	P45983	MAPK8	S135	E130K	130	Missense	distal	-5	no	9.420	9.343	PhosphoSitePlus	COSMIC	2.638	Down-regulation
CMGC_MAPK_JNK_MAPK8_ST	Q9H2B2	SYT4	P45983	MAPK8	S135	P136L	136	Missense	proximal	1	no	9.420	1.847	PhosphoSitePlus	COSMIC	2.638	Loss
CMGC_MAPK_JNK_MAPK8_ST	Q9H2B2	SYT4	P45983	MAPK8	S135	P136S	136	Missense	proximal	1	no	9.420	1.691	PhosphoSitePlus	COSMIC	2.638	Loss
CMGC_MAPK_JNK_MAPK8_ST	Q9H2B2	SYT4	P45983	MAPK8	S135	S133P	133	Missense	proximal	-2	no	9.420	9.525	PhosphoSitePlus	COSMIC	2.638	Up-regulation
CMGC_MAPK_JNK_MAPK8_ST	Q9H2B2	SYT4	P45983	MAPK8	S135	S138R	138	Missense	distal	3	no	9.420	9.602	PhosphoSitePlus	COSMIC	2.638	Up-regulation
CMGC_MAPK_JNK_MAPK8_ST	Q9H2B2	SYT4	P45983	MAPK8	S135	P136T	136	Missense	proximal	1	no	9.420	2.433	PhosphoSitePlus	COSMIC	2.638	Loss
CMGC_MAPK_JNK_MAPK8_ST	Q9H2B2	SYT4	P45983	MAPK8	S135	S141P	141	Missense	distal	6	no	9.420	9.395	PhosphoSitePlus	COSMIC	2.638	Down-regulation
CMGC_MAPK_JNK_MAPK8_ST	Q9H2B2	SYT4	P45983	MAPK8	S138	L139P	139	Missense	proximal	1	no	0.929	8.502	EPSD	COSMIC	2.638	Gain
CMGC_MAPK_JNK_MAPK8_ST	Q9H2B2	SYT4	P45983	MAPK8	T156	L157P	157	Missense	proximal	1	no	0.324	7.897	EPSD	COSMIC	2.638	Gain
CMGC_MAPK_JNK_MAPK8_ST	Q16621	NFE2	P45983	MAPK8	S2	S9R	9	Missense	distal	7	no	7.248	7.311	EPSD	COSMIC	2.638	Up-regulation
CMGC_MAPK_JNK_MAPK8_ST	Q16621	NFE2	P45983	MAPK8	S107	L112F	112	Missense	distal	5	no	2.972	2.966	EPSD	COSMIC	2.638	Down-regulation
CMGC_MAPK_JNK_MAPK8_ST	Q16621	NFE2	P45983	MAPK8	S346	A351V	351	Missense	distal	5	no	8.549	8.622	EPSD	COSMIC	2.638	Up-regulation
CAMK_CAMKL_MARK_MARK3_ST	Q06413	MEF2C	P27448	MARK3	S59	D61N	61	Missense	proximal	2	no	272.923	280.856	EPSD	COSMIC	255.132	Up-regulation
CAMK_CAMKL_MARK_MARK3_ST	Q06413	MEF2C	P27448	MARK3	S59	A58T	58	Missense	proximal	-1	no	272.923	272.929	EPSD	COSMIC;GDSC;CCLE	255.132	Up-regulation
CAMK_CAMKL_MARK_MARK3_ST	Q06413	MEF2C	P27448	MARK3	T80	P75L	75	Missense	distal	-5	no	192.141	300.044	EPSD	COSMIC	255.132	Gain
CAMK_CAMKL_MARK_MARK3_ST	Q06413	MEF2C	P27448	MARK3	S82	E77K	77	Missense	distal	-5	no	230.623	343.911	EPSD	COSMIC	255.132	Gain
CAMK_CAMKL_MARK_MARK3_ST	Q06413	MEF2C	P27448	MARK3	S98	K91E	91	Missense	distal	-7	no	283.062	276.581	EPSD	COSMIC	255.132	Down-regulation
CAMK_CAMKL_MARK_MARK3_ST	Q06413	MEF2C	P27448	MARK3	S98	C96S	96	Missense	proximal	-2	no	283.062	276.631	EPSD	COSMIC;GDSC;CCLE	255.132	Down-regulation
CAMK_CAMKL_MARK_MARK3_ST	Q06413	MEF2C	P27448	MARK3	S98	D100N	100	Missense	proximal	2	no	283.062	290.995	EPSD	COSMIC	255.132	Up-regulation
CAMK_CAMKL_MARK_MARK3_ST	Q06413	MEF2C	P27448	MARK3	S98	G95C	95	Missense	distal	-3	no	283.062	310.092	EPSD	COSMIC	255.132	Up-regulation
CAMK_CAMKL_MARK_MARK3_ST	Q06413	MEF2C	P27448	MARK3	S98	K91N	91	Missense	distal	-7	no	283.062	278.469	EPSD	COSMIC	255.132	Down-regulation
CAMK_CAMKL_MARK_MARK3_ST	Q06413	MEF2C	P27448	MARK3	S98	A103S	103	Missense	distal	5	no	283.062	275.289	EPSD	COSMIC	255.132	Down-regulation
CAMK_CAMKL_MARK_MARK3_ST	Q06413	MEF2C	P27448	MARK3	S98	K91R	91	Missense	distal	-7	no	283.062	278.286	EPSD	COSMIC	255.132	Down-regulation
CAMK_CAMKL_MARK_MARK3_ST	Q06413	MEF2C	P27448	MARK3	S192	G185D	185	Missense	distal	-7	no	314.836	321.293	EPSD	COSMIC	255.132	Up-regulation
CAMK_CAMKL_MARK_MARK3_ST	Q06413	MEF2C	P27448	MARK3	S192	L199P	199	Missense	distal	7	no	314.836	314.738	EPSD	COSMIC	255.132	Down-regulation
CAMK_CAMKL_MARK_MARK3_ST	Q06413	MEF2C	P27448	MARK3	S222	G215R	215	Missense	distal	-7	no	529.076	537.009	PhosphoSitePlus	COSMIC	255.132	Up-regulation
CAMK_CAMKL_MARK_MARK3_ST	Q06413	MEF2C	P27448	MARK3	S222	S222P	222	Missense	central	0	yes	529.076	0.000	PhosphoSitePlus	COSMIC	255.132	Loss
CAMK_CAMKL_MARK_MARK3_ST	Q06413	MEF2C	P27448	MARK3	S222	N221H	221	Missense	proximal	-1	no	529.076	529.997	PhosphoSitePlus	COSMIC	255.132	Up-regulation
CAMK_CAMKL_MARK_MARK3_ST	Q06413	MEF2C	P27448	MARK3	S222	G215E	215	Missense	distal	-7	no	529.076	535.304	PhosphoSitePlus	COSMIC	255.132	Up-regulation
CAMK_CAMKL_MARK_MARK3_ST	Q06413	MEF2C	P27448	MARK3	S222	N218H	218	Missense	distal	-4	no	529.076	502.026	PhosphoSitePlus	COSMIC	255.132	Down-regulation
CAMK_CAMKL_MARK_MARK3_ST	Q06413	MEF2C	P27448	MARK3	S387	S387P	387	Missense	central	0	yes	325.011	0.000	EPSD	COSMIC	255.132	Loss
CAMK_CAMKL_MARK_MARK3_ST	Q06413	MEF2C	P27448	MARK3	S387	N389S	389	Missense	proximal	2	no	325.011	268.673	EPSD	COSMIC;GDSC	255.132	Down-regulation
CAMK_CAMKL_MARK_MARK3_ST	Q06413	MEF2C	P27448	MARK3	S387	S384C	384	Missense	distal	-3	no	325.011	327.032	EPSD	COSMIC	255.132	Up-regulation
CAMK_CAMKL_MARK_MARK3_ST	Q06413	MEF2C	P27448	MARK3	S387	L388F	388	Missense	proximal	1	no	325.011	325.025	EPSD	COSMIC	255.132	Up-regulation
CAMK_CAMKL_MARK_MARK3_ST	Q06413	MEF2C	P27448	MARK3	S387	L380I	380	Missense	distal	-7	no	325.011	322.901	EPSD	COSMIC	255.132	Down-regulation
CAMK_CAMKL_MARK_MARK3_ST	Q06413	MEF2C	P27448	MARK3	S387	S381G	381	Missense	distal	-6	no	325.011	324.587	EPSD	COSMIC	255.132	Down-regulation
CAMK_CAMKL_MARK_MARK3_ST	Q06413	MEF2C	P27448	MARK3	S387	I390M	390	Missense	distal	3	no	325.011	324.610	EPSD	COSMIC	255.132	Down-regulation
CAMK_CAMKL_MARK_MARK3_ST	Q06413	MEF2C	P27448	MARK3	S387	P394R	394	Missense	distal	7	no	325.011	325.578	EPSD	COSMIC	255.132	Up-regulation
CAMK_CAMKL_MARK_MARK3_ST	Q06413	MEF2C	P27448	MARK3	S387	P394T	394	Missense	distal	7	no	325.011	324.777	EPSD	COSMIC	255.132	Down-regulation
CAMK_CAMKL_MARK_MARK3_ST	Q06413	MEF2C	P27448	MARK3	S396	S396L	396	Missense	central	0	yes	314.015	0.000	EPSD	COSMIC	255.132	Loss
CAMK_CAMKL_MARK_MARK3_ST	Q06413	MEF2C	P27448	MARK3	S396	T402M	402	Missense	distal	6	no	314.015	308.845	EPSD	COSMIC	255.132	Down-regulation
CAMK_CAMKL_MARK_MARK3_ST	Q06413	MEF2C	P27448	MARK3	S396	D400Y	400	Missense	distal	4	no	314.015	314.125	EPSD	COSMIC	255.132	Up-regulation
CAMK_CAMKL_MARK_MARK3_ST	Q06413	MEF2C	P27448	MARK3	S396	N389S	389	Missense	distal	-7	no	314.015	311.458	EPSD	COSMIC;GDSC	255.132	Down-regulation
CAMK_CAMKL_MARK_MARK3_ST	Q06413	MEF2C	P27448	MARK3	S396	I390M	390	Missense	distal	-6	no	314.015	312.548	EPSD	COSMIC	255.132	Down-regulation
CAMK_CAMKL_MARK_MARK3_ST	Q06413	MEF2C	P27448	MARK3	S396	R401T	401	Missense	distal	5	no	314.015	314.845	EPSD	COSMIC	255.132	Up-regulation
CAMK_CAMKL_MARK_MARK3_ST	Q06413	MEF2C	P27448	MARK3	S396	R401K	401	Missense	distal	5	no	314.015	349.880	EPSD	COSMIC	255.132	Up-regulation
CAMK_CAMKL_MARK_MARK3_ST	Q06413	MEF2C	P27448	MARK3	S396	P394R	394	Missense	proximal	-2	no	314.015	323.983	EPSD	COSMIC	255.132	Up-regulation
CAMK_CAMKL_MARK_MARK3_ST	Q06413	MEF2C	P27448	MARK3	S396	P394T	394	Missense	proximal	-2	no	314.015	308.739	EPSD	COSMIC	255.132	Down-regulation
CAMK_CAMKL_MARK_MARK3_ST	Q06413	MEF2C	P27448	MARK3	S406	R401K	401	Missense	distal	-5	no	209.586	304.481	EPSD	COSMIC	255.132	Gain
CAMK_CAMKL_MARK_MARK3_ST	Q06413	MEF2C	P27448	MARK3	S430	S428L	428	Missense	proximal	-2	no	248.624	255.813	EPSD	COSMIC	255.132	Gain
CAMK_CAMKL_MARK_MARK3_ST	Q06413	MEF2C	P27448	MARK3	S430	R436L	436	Missense	distal	6	no	248.624	262.279	EPSD	COSMIC	255.132	Gain
CAMK_CAMKL_MARK_MARK3_ST	Q06413	MEF2C	P27448	MARK3	S430	D435N	435	Missense	distal	5	no	248.624	288.855	EPSD	COSMIC	255.132	Gain
CAMK_CAMKL_MARK_MARK3_ST	Q06413	MEF2C	P27448	MARK3	S445	E442K	442	Missense	distal	-3	no	250.870	285.128	EPSD	COSMIC;GDSC;CCLE	255.132	Gain
CAMK_CAMKL_MARK_MARK3_ST	Q06413	MEF2C	P27448	MARK3	S445	R451K	451	Missense	distal	6	no	250.870	274.603	EPSD	COSMIC	255.132	Gain
CAMK_CAMKL_MARK_MARK3_ST	Q06413	MEF2C	P27448	MARK3	S445	R440K	440	Missense	distal	-5	no	250.870	345.765	EPSD	COSMIC	255.132	Gain
CAMK_CAMKL_MARK_MARK3_ST	Q99689	FEZ1	P27448	MARK3	T136	E140D	140	Missense	distal	4	no	257.380	257.951	EPSD	COSMIC	255.132	Up-regulation
CAMK_CAMKL_MARK_MARK3_ST	Q99689	FEZ1	P27448	MARK3	T136	E142D	142	Missense	distal	6	no	257.380	246.840	EPSD	COSMIC	255.132	Loss
CAMK_CAMKL_MARK_MARK3_ST	Q99689	FEZ1	P27448	MARK3	T136	I138F	138	Missense	proximal	2	no	257.380	264.798	EPSD	COSMIC	255.132	Up-regulation
CAMK_CAMKL_MARK_MARK3_ST	Q92974	ARHGEF2	P27448	MARK3	S2	R3W	3	Missense	proximal	1	no	338.702	338.716	EPSD	COSMIC	255.132	Up-regulation
CAMK_CAMKL_MARK_MARK3_ST	Q92974	ARHGEF2	P27448	MARK3	S2	E5A	5	Missense	distal	3	no	338.702	338.060	EPSD	COSMIC;CCLE	255.132	Down-regulation
CAMK_CAMKL_MARK_MARK3_ST	Q92974	ARHGEF2	P27448	MARK3	S6	R3W	3	Missense	distal	-3	no	388.794	349.051	EPSD	COSMIC	255.132	Down-regulation
CAMK_CAMKL_MARK_MARK3_ST	Q92974	ARHGEF2	P27448	MARK3	S6	E5A	5	Missense	proximal	-1	no	388.794	388.802	EPSD	COSMIC;CCLE	255.132	Up-regulation
CAMK_CAMKL_MARK_MARK3_ST	Q92974	ARHGEF2	P27448	MARK3	S46	S48L	48	Missense	proximal	2	no	308.387	336.720	EPSD	COSMIC	255.132	Up-regulation
CAMK_CAMKL_MARK_MARK3_ST	Q92974	ARHGEF2	P27448	MARK3	S46	F42V	42	Missense	distal	-4	no	308.387	314.052	EPSD	COSMIC	255.132	Up-regulation
CAMK_CAMKL_MARK_MARK3_ST	Q92974	ARHGEF2	P27448	MARK3	S109	R111Q	111	Missense	proximal	2	no	292.759	273.271	EPSD	COSMIC	255.132	Down-regulation
CAMK_CAMKL_MARK_MARK3_ST	Q92974	ARHGEF2	P27448	MARK3	S109	A104T	104	Missense	distal	-5	no	292.759	326.837	EPSD	COSMIC;CCLE	255.132	Up-regulation
CAMK_CAMKL_MARK_MARK3_ST	Q92974	ARHGEF2	P27448	MARK3	S109	R111S	111	Missense	proximal	2	no	292.759	261.972	EPSD	COSMIC	255.132	Down-regulation
CAMK_CAMKL_MARK_MARK3_ST	Q92974	ARHGEF2	P27448	MARK3	S121	Y125S	125	Missense	distal	4	no	291.536	290.803	EPSD	COSMIC	255.132	Down-regulation
CAMK_CAMKL_MARK_MARK3_ST	Q92974	ARHGEF2	P27448	MARK3	S121	D128Y	128	Missense	distal	7	no	291.536	292.620	EPSD	COSMIC	255.132	Up-regulation
CAMK_CAMKL_MARK_MARK3_ST	Q92974	ARHGEF2	P27448	MARK3	S121	D128E	128	Missense	distal	7	no	291.536	291.159	EPSD	COSMIC	255.132	Down-regulation
CAMK_CAMKL_MARK_MARK3_ST	Q92974	ARHGEF2	P27448	MARK3	S121	S122L	122	Missense	proximal	1	no	291.536	291.522	EPSD	COSMIC	255.132	Down-regulation
CAMK_CAMKL_MARK_MARK3_ST	Q92974	ARHGEF2	P27448	MARK3	S127	S122L	122	Missense	distal	-5	no	182.462	267.713	EPSD	COSMIC	255.132	Gain
CAMK_CAMKL_MARK_MARK3_ST	Q92974	ARHGEF2	P27448	MARK3	S142	S137F	137	Missense	distal	-5	no	286.251	274.602	EPSD	COSMIC	255.132	Down-regulation
CAMK_CAMKL_MARK_MARK3_ST	Q92974	ARHGEF2	P27448	MARK3	S142	R138S	138	Missense	distal	-4	no	286.251	280.886	EPSD	COSMIC	255.132	Down-regulation
CAMK_CAMKL_MARK_MARK3_ST	Q92974	ARHGEF2	P27448	MARK3	S142	R141S	141	Missense	proximal	-1	no	286.251	287.142	EPSD	COSMIC	255.132	Up-regulation
CAMK_CAMKL_MARK_MARK3_ST	Q92974	ARHGEF2	P27448	MARK3	S142	R141C	141	Missense	proximal	-1	no	286.251	286.880	EPSD	COSMIC	255.132	Up-regulation
CAMK_CAMKL_MARK_MARK3_ST	Q92974	ARHGEF2	P27448	MARK3	S142	R141L	141	Missense	proximal	-1	no	286.251	286.656	EPSD	COSMIC	255.132	Up-regulation
CAMK_CAMKL_MARK_MARK3_ST	Q92974	ARHGEF2	P27448	MARK3	S143	S137F	137	Missense	distal	-6	no	373.920	373.293	EPSD	COSMIC	255.132	Down-regulation
CAMK_CAMKL_MARK_MARK3_ST	Q92974	ARHGEF2	P27448	MARK3	S143	R138S	138	Missense	distal	-5	no	373.920	355.701	EPSD	COSMIC	255.132	Down-regulation
CAMK_CAMKL_MARK_MARK3_ST	Q92974	ARHGEF2	P27448	MARK3	S143	R141S	141	Missense	proximal	-2	no	373.920	357.601	EPSD	COSMIC	255.132	Down-regulation
CAMK_CAMKL_MARK_MARK3_ST	Q92974	ARHGEF2	P27448	MARK3	S143	R141C	141	Missense	proximal	-2	no	373.920	364.033	EPSD	COSMIC	255.132	Down-regulation
CAMK_CAMKL_MARK_MARK3_ST	Q92974	ARHGEF2	P27448	MARK3	S143	R141L	141	Missense	proximal	-2	no	373.920	364.789	EPSD	COSMIC	255.132	Down-regulation
CAMK_CAMKL_MARK_MARK3_ST	Q92974	ARHGEF2	P27448	MARK3	S172	S174P	174	Missense	proximal	2	no	335.738	405.749	EPSD	COSMIC	255.132	Up-regulation
CAMK_CAMKL_MARK_MARK3_ST	Q92974	ARHGEF2	P27448	MARK3	S172	R168L	168	Missense	distal	-4	no	335.738	323.775	EPSD	COSMIC	255.132	Down-regulation
CAMK_CAMKL_MARK_MARK3_ST	Q92974	ARHGEF2	P27448	MARK3	S172	T175K	175	Missense	distal	3	no	335.738	334.699	EPSD	COSMIC	255.132	Down-regulation
CAMK_CAMKL_MARK_MARK3_ST	Q92974	ARHGEF2	P27448	MARK3	S177	R183S	183	Missense	distal	6	no	297.025	287.516	EPSD	COSMIC	255.132	Down-regulation
CAMK_CAMKL_MARK_MARK3_ST	Q92974	ARHGEF2	P27448	MARK3	S177	S174P	174	Missense	distal	-3	no	297.025	289.880	EPSD	COSMIC	255.132	Down-regulation
CAMK_CAMKL_MARK_MARK3_ST	Q92974	ARHGEF2	P27448	MARK3	S177	T175K	175	Missense	proximal	-2	no	297.025	316.874	EPSD	COSMIC	255.132	Up-regulation
CAMK_CAMKL_MARK_MARK3_ST	Q92974	ARHGEF2	P27448	MARK3	S186	R183S	183	Missense	distal	-3	no	344.357	324.607	EPSD	COSMIC	255.132	Down-regulation
CAMK_CAMKL_MARK_MARK3_ST	Q92974	ARHGEF2	P27448	MARK3	S186	S186F	186	Missense	central	0	yes	344.357	0.000	EPSD	COSMIC	255.132	Loss
CAMK_CAMKL_MARK_MARK3_ST	Q92974	ARHGEF2	P27448	MARK3	S696	D690H	690	Missense	distal	-6	no	263.875	266.218	EPSD	COSMIC	255.132	Up-regulation
CAMK_CAMKL_MARK_MARK3_ST	Q92974	ARHGEF2	P27448	MARK3	S696	G703A	703	Missense	distal	7	no	263.875	264.792	EPSD	COSMIC	255.132	Up-regulation
CAMK_CAMKL_MARK_MARK3_ST	Q92974	ARHGEF2	P27448	MARK3	T707	G703A	703	Missense	distal	-4	no	246.783	265.901	EPSD	COSMIC	255.132	Gain
CAMK_CAMKL_MARK_MARK3_ST	Q92974	ARHGEF2	P27448	MARK3	S711	N709S	709	Missense	proximal	-2	no	271.732	257.814	EPSD	COSMIC	255.132	Down-regulation
CAMK_CAMKL_MARK_MARK3_ST	Q92974	ARHGEF2	P27448	MARK3	S711	D718H	718	Missense	distal	7	no	271.732	273.468	EPSD	COSMIC	255.132	Up-regulation
CAMK_CAMKL_MARK_MARK3_ST	Q92974	ARHGEF2	P27448	MARK3	S719	S721C	721	Missense	proximal	2	no	247.311	256.407	EPSD	COSMIC	255.132	Gain
CAMK_CAMKL_MARK_MARK3_ST	Q92974	ARHGEF2	P27448	MARK3	T830	R828W	828	Missense	proximal	-2	no	288.760	276.843	EPSD	COSMIC	255.132	Down-regulation
CAMK_CAMKL_MARK_MARK3_ST	Q92974	ARHGEF2	P27448	MARK3	T830	R828Q	828	Missense	proximal	-2	no	288.760	287.325	EPSD	COSMIC	255.132	Down-regulation
CAMK_CAMKL_MARK_MARK3_ST	Q92974	ARHGEF2	P27448	MARK3	T830	E827Q	827	Missense	distal	-3	no	288.760	289.320	EPSD	COSMIC	255.132	Up-regulation
CAMK_CAMKL_MARK_MARK3_ST	Q92974	ARHGEF2	P27448	MARK3	T830	R823C	823	Missense	distal	-7	no	288.760	284.309	EPSD	COSMIC	255.132	Down-regulation
CAMK_CAMKL_MARK_MARK3_ST	Q92974	ARHGEF2	P27448	MARK3	T830	E826K	826	Missense	distal	-4	no	288.760	309.585	EPSD	COSMIC	255.132	Up-regulation
CAMK_CAMKL_MARK_MARK3_ST	Q92974	ARHGEF2	P27448	MARK3	T830	A829P	829	Missense	proximal	-1	no	288.760	288.617	EPSD	COSMIC	255.132	Down-regulation
CAMK_CAMKL_MARK_MARK3_ST	Q92974	ARHGEF2	P27448	MARK3	T830	E831K	831	Missense	proximal	1	no	288.760	288.744	EPSD	COSMIC	255.132	Down-regulation
CAMK_CAMKL_MARK_MARK3_ST	Q92974	ARHGEF2	P27448	MARK3	S886	R885W	885	Missense	proximal	-1	no	293.478	294.158	EPSD	COSMIC	255.132	Up-regulation
CAMK_CAMKL_MARK_MARK3_ST	Q92974	ARHGEF2	P27448	MARK3	S886	R883Q	883	Missense	distal	-3	no	293.478	265.529	EPSD	COSMIC	255.132	Down-regulation
CAMK_CAMKL_MARK_MARK3_ST	Q92974	ARHGEF2	P27448	MARK3	S886	R884C	884	Missense	proximal	-2	no	293.478	283.590	EPSD	COSMIC	255.132	Down-regulation
CAMK_CAMKL_MARK_MARK3_ST	Q92974	ARHGEF2	P27448	MARK3	S886	R884H	884	Missense	proximal	-2	no	293.478	277.677	EPSD	COSMIC	255.132	Down-regulation
CAMK_CAMKL_MARK_MARK3_ST	Q92974	ARHGEF2	P27448	MARK3	S886	R885C	885	Missense	proximal	-1	no	293.478	294.108	EPSD	COSMIC;CCLE	255.132	Up-regulation
CAMK_CAMKL_MARK_MARK3_ST	Q92974	ARHGEF2	P27448	MARK3	S886	L887F	887	Missense	proximal	1	no	293.478	293.492	EPSD	COSMIC	255.132	Up-regulation
CAMK_CAMKL_MARK_MARK3_ST	Q92974	ARHGEF2	P27448	MARK3	S886	P882L	882	Missense	distal	-4	no	293.478	295.834	EPSD	COSMIC	255.132	Up-regulation
CAMK_CAMKL_MARK_MARK3_ST	Q92974	ARHGEF2	P27448	MARK3	S886	P888S	888	Missense	proximal	2	no	293.478	223.467	EPSD	COSMIC	255.132	Loss
CAMK_CAMKL_MARK_MARK3_ST	Q92974	ARHGEF2	P27448	MARK3	S886	P888L	888	Missense	proximal	2	no	293.478	251.800	EPSD	COSMIC	255.132	Loss
CAMK_CAMKL_MARK_MARK3_ST	Q92974	ARHGEF2	P27448	MARK3	S903	R908W	908	Missense	distal	5	no	432.035	422.821	EPSD	COSMIC	255.132	Down-regulation
CAMK_CAMKL_MARK_MARK3_ST	Q92974	ARHGEF2	P27448	MARK3	S903	R908C	908	Missense	distal	5	no	432.035	418.152	EPSD	COSMIC	255.132	Down-regulation
CAMK_CAMKL_MARK_MARK3_ST	Q92974	ARHGEF2	P27448	MARK3	S903	R904Q	904	Missense	proximal	1	no	432.035	432.051	EPSD	COSMIC	255.132	Up-regulation
CAMK_CAMKL_MARK_MARK3_ST	Q92974	ARHGEF2	P27448	MARK3	S947	S941R	941	Missense	distal	-6	no	300.629	297.192	EPSD	COSMIC	255.132	Down-regulation
CAMK_CAMKL_MARK_MARK3_ST	Q92974	ARHGEF2	P27448	MARK3	S947	S952R	952	Missense	distal	5	no	300.629	295.794	EPSD	COSMIC	255.132	Down-regulation
CAMK_CAMKL_MARK_MARK3_ST	Q92974	ARHGEF2	P27448	MARK3	S947	G951E	951	Missense	distal	4	no	300.629	300.006	EPSD	COSMIC	255.132	Down-regulation
CAMK_CAMKL_MARK_MARK3_ST	Q92974	ARHGEF2	P27448	MARK3	S947	E948Q	948	Missense	proximal	1	no	300.629	300.643	EPSD	COSMIC	255.132	Up-regulation
CAMK_CAMKL_MARK_MARK3_ST	Q92974	ARHGEF2	P27448	MARK3	S947	G946D	946	Missense	proximal	-1	no	300.629	300.399	EPSD	COSMIC	255.132	Down-regulation
CAMK_CAMKL_MARK_MARK3_ST	Q92974	ARHGEF2	P27448	MARK3	S947	S952T	952	Missense	distal	5	no	300.629	296.623	EPSD	COSMIC	255.132	Down-regulation
CAMK_CAMKL_MARK_MARK3_ST	Q92974	ARHGEF2	P27448	MARK3	S956	S952R	952	Missense	distal	-4	no	270.831	276.196	EPSD	COSMIC	255.132	Up-regulation
CAMK_CAMKL_MARK_MARK3_ST	Q92974	ARHGEF2	P27448	MARK3	S956	G951E	951	Missense	distal	-5	no	270.831	251.417	EPSD	COSMIC	255.132	Loss
CAMK_CAMKL_MARK_MARK3_ST	Q92974	ARHGEF2	P27448	MARK3	S956	S952T	952	Missense	distal	-4	no	270.831	267.252	EPSD	COSMIC	255.132	Down-regulation
CAMK_CAMKL_MARK_MARK3_ST	Q92974	ARHGEF2	P27448	MARK3	S956	L955V	955	Missense	proximal	-1	no	270.831	271.281	EPSD	COSMIC	255.132	Up-regulation
CAMK_CAMKL_MARK_MARK3_ST	Q92974	ARHGEF2	P27448	MARK3	S960	L955V	955	Missense	distal	-5	no	304.537	202.558	EPSD	COSMIC	255.132	Loss
CAMK_CAMKL_MARK_MARK3_ST	P41236	PPP1R2	P27448	MARK3	S7	S4W	4	Missense	distal	-3	no	327.320	307.327	EPSD	COSMIC	255.132	Down-regulation
CAMK_CAMKL_MARK_MARK3_ST	P41236	PPP1R2	P27448	MARK3	T19	M25V	25	Missense	distal	6	no	291.085	280.473	EPSD	COSMIC	255.132	Down-regulation
CAMK_CAMKL_MARK_MARK3_ST	P41236	PPP1R2	P27448	MARK3	S20	M25V	25	Missense	distal	5	no	482.335	466.200	EPSD	COSMIC	255.132	Down-regulation
CAMK_CAMKL_MARK_MARK3_ST	P41236	PPP1R2	P27448	MARK3	T21	M25V	25	Missense	distal	4	no	299.850	300.474	EPSD	COSMIC	255.132	Up-regulation
CAMK_CAMKL_MARK_MARK3_ST	P41236	PPP1R2	P27448	MARK3	T21	S28L	28	Missense	distal	7	no	299.850	298.950	EPSD	COSMIC	255.132	Down-regulation
CAMK_CAMKL_MARK_MARK3_ST	P41236	PPP1R2	P27448	MARK3	S23	M25V	25	Missense	proximal	2	no	345.708	313.753	EPSD	COSMIC	255.132	Down-regulation
CAMK_CAMKL_MARK_MARK3_ST	P41236	PPP1R2	P27448	MARK3	S23	S28L	28	Missense	distal	5	no	345.708	357.104	EPSD	COSMIC	255.132	Up-regulation
CAMK_CAMKL_MARK_MARK3_ST	P41236	PPP1R2	P27448	MARK3	S24	M25V	25	Missense	proximal	1	no	311.243	311.252	EPSD	COSMIC	255.132	Up-regulation
CAMK_CAMKL_MARK_MARK3_ST	P41236	PPP1R2	P27448	MARK3	S28	R33C	33	Missense	distal	5	no	264.959	251.075	EPSD	COSMIC	255.132	Loss
CAMK_CAMKL_MARK_MARK3_ST	P41236	PPP1R2	P27448	MARK3	S28	M25V	25	Missense	distal	-3	no	264.959	244.343	EPSD	COSMIC	255.132	Loss
CAMK_CAMKL_MARK_MARK3_ST	P41236	PPP1R2	P27448	MARK3	S28	S28L	28	Missense	central	0	yes	264.959	0.000	EPSD	COSMIC	255.132	Loss
CAMK_CAMKL_MARK_MARK3_ST	P30307	CDC25C	P27448	MARK3	S57	L54V	54	Missense	distal	-3	no	268.784	255.079	EPSD	COSMIC	255.132	Loss
CAMK_CAMKL_MARK_MARK3_ST	P30307	CDC25C	P27448	MARK3	S57	V50A	50	Missense	distal	-7	no	268.784	280.021	EPSD	COSMIC	255.132	Up-regulation
CAMK_CAMKL_MARK_MARK3_ST	P30307	CDC25C	P27448	MARK3	S57	F53L	53	Missense	distal	-4	no	268.784	274.760	EPSD	COSMIC	255.132	Up-regulation
CAMK_CAMKL_MARK_MARK3_ST	P30307	CDC25C	P27448	MARK3	S168	S168F	168	Missense	central	0	yes	305.962	0.000	EPSD	COSMIC	255.132	Loss
CAMK_CAMKL_MARK_MARK3_ST	P30307	CDC25C	P27448	MARK3	S168	S161L	161	Missense	distal	-7	no	305.962	303.451	EPSD	COSMIC	255.132	Down-regulation
CAMK_CAMKL_MARK_MARK3_ST	P30307	CDC25C	P27448	MARK3	T171	S168F	168	Missense	distal	-3	no	360.911	346.905	EPSD	COSMIC	255.132	Down-regulation
CAMK_CAMKL_MARK_MARK3_ST	P30307	CDC25C	P27448	MARK3	S191	E189K	189	Missense	proximal	-2	no	248.497	266.222	EPSD	COSMIC	255.132	Gain
CAMK_CAMKL_MARK_MARK3_ST	P30307	CDC25C	P27448	MARK3	S191	E189D	189	Missense	proximal	-2	no	248.497	258.107	EPSD	COSMIC	255.132	Gain
CAMK_CAMKL_MARK_MARK3_ST	P30307	CDC25C	P27448	MARK3	S214	S216L	216	Missense	proximal	2	no	289.286	317.618	EPSD	COSMIC	255.132	Up-regulation
CAMK_CAMKL_MARK_MARK3_ST	P30307	CDC25C	P27448	MARK3	S214	G210R	210	Missense	distal	-4	no	289.286	311.805	EPSD	COSMIC	255.132	Up-regulation
CAMK_CAMKL_MARK_MARK3_ST	P30307	CDC25C	P27448	MARK3	S216	S216L	216	Missense	central	0	yes	655.162	0.000	PhosphoSitePlus	COSMIC	255.132	Loss
CAMK_CAMKL_MARK_MARK3_ST	P30307	CDC25C	P27448	MARK3	S216	G210R	210	Missense	distal	-6	no	655.162	652.149	PhosphoSitePlus	COSMIC	255.132	Down-regulation
CAMK_CAMKL_MARK_MARK3_ST	P30307	CDC25C	P27448	MARK3	S247	S247F	247	Missense	central	0	yes	296.754	0.000	EPSD	COSMIC	255.132	Loss
CAMK_CAMKL_MARK_MARK3_ST	P30307	CDC25C	P27448	MARK3	S247	Y245S	245	Missense	proximal	-2	no	296.754	296.877	EPSD	COSMIC	255.132	Up-regulation
CAMK_CAMKL_MARK_MARK3_ST	P30307	CDC25C	P27448	MARK3	S247	K244T	244	Missense	distal	-3	no	296.754	267.016	EPSD	COSMIC	255.132	Down-regulation
CAMK_CAMKL_MARK_MARK3_ST	P30307	CDC25C	P27448	MARK3	S247	G250E	250	Missense	distal	3	no	296.754	295.847	EPSD	COSMIC	255.132	Down-regulation
CAMK_CAMKL_MARK_MARK3_ST	P30307	CDC25C	P27448	MARK3	S247	G250W	250	Missense	distal	3	no	296.754	296.286	EPSD	COSMIC	255.132	Down-regulation
CAMK_CAMKL_MARK_MARK3_ST	P30307	CDC25C	P27448	MARK3	S247	S247C	247	Missense	central	0	yes	296.754	0.000	EPSD	COSMIC	255.132	Loss
CAMK_CAMKL_MARK_MARK3_ST	P30307	CDC25C	P27448	MARK3	S263	D266H	266	Missense	distal	3	no	260.518	261.193	EPSD	COSMIC	255.132	Up-regulation
CAMK_CAMKL_MARK_MARK3_ST	P30307	CDC25C	P27448	MARK3	S263	L264R	264	Missense	proximal	1	no	260.518	260.515	EPSD	COSMIC	255.132	Down-regulation
CAMK_CAMKL_MARK_MARK3_ST	P30307	CDC25C	P27448	MARK3	S277	D276N	276	Missense	proximal	-1	no	307.253	306.794	EPSD	COSMIC	255.132	Down-regulation
AGC_Akt_AKT2_ST	Q04656	ATP7A	P31751	AKT2	S262	K256Q	256	Missense	distal	-6	no	26.611	26.331	EPSD	COSMIC	19.022	Down-regulation
AGC_Akt_AKT2_ST	Q04656	ATP7A	P31751	AKT2	S262	Q268H	268	Missense	distal	6	no	26.611	26.116	EPSD	COSMIC	19.022	Down-regulation
AGC_Akt_AKT2_ST	Q04656	ATP7A	P31751	AKT2	S272	N275S	275	Missense	distal	3	no	23.452	23.062	EPSD	COSMIC	19.022	Down-regulation
AGC_Akt_AKT2_ST	Q04656	ATP7A	P31751	AKT2	S272	T278P	278	Missense	distal	6	no	23.452	23.309	EPSD	COSMIC	19.022	Down-regulation
AGC_Akt_AKT2_ST	Q04656	ATP7A	P31751	AKT2	S272	A279T	279	Missense	distal	7	no	23.452	22.706	EPSD	COSMIC	19.022	Down-regulation
AGC_Akt_AKT2_ST	Q04656	ATP7A	P31751	AKT2	S272	Q268H	268	Missense	distal	-4	no	23.452	23.848	EPSD	COSMIC	19.022	Up-regulation
AGC_Akt_AKT2_ST	Q04656	ATP7A	P31751	AKT2	T274	N275S	275	Missense	proximal	1	no	26.304	26.291	EPSD	COSMIC	19.022	Down-regulation
AGC_Akt_AKT2_ST	Q04656	ATP7A	P31751	AKT2	T274	T278P	278	Missense	distal	4	no	26.304	26.470	EPSD	COSMIC	19.022	Up-regulation
AGC_Akt_AKT2_ST	Q04656	ATP7A	P31751	AKT2	T274	A279T	279	Missense	distal	5	no	26.304	25.980	EPSD	COSMIC	19.022	Down-regulation
AGC_Akt_AKT2_ST	Q04656	ATP7A	P31751	AKT2	T274	Q268H	268	Missense	distal	-6	no	26.304	26.598	EPSD	COSMIC	19.022	Up-regulation
AGC_Akt_AKT2_ST	Q04656	ATP7A	P31751	AKT2	S360	N356S	356	Missense	distal	-4	no	21.226	21.377	EPSD	COSMIC	19.022	Up-regulation
AGC_Akt_AKT2_ST	Q04656	ATP7A	P31751	AKT2	S639	D635A	635	Missense	distal	-4	no	24.731	24.265	EPSD	COSMIC;GDSC;CCLE	19.022	Down-regulation
AGC_Akt_AKT2_ST	Q04656	ATP7A	P31751	AKT2	S639	V632A	632	Missense	distal	-7	no	24.731	24.876	EPSD	COSMIC	19.022	Up-regulation
AGC_Akt_AKT2_ST	Q04656	ATP7A	P31751	AKT2	S639	R645Q	645	Missense	distal	6	no	24.731	23.943	EPSD	COSMIC;GDSC	19.022	Down-regulation
AGC_Akt_AKT2_ST	Q04656	ATP7A	P31751	AKT2	S1146	S1146F	1146	Missense	central	0	yes	22.345	0.000	EPSD	COSMIC	19.022	Loss
AGC_Akt_AKT2_ST	Q04656	ATP7A	P31751	AKT2	S1146	N1144I	1144	Missense	proximal	-2	no	22.345	23.106	EPSD	COSMIC	19.022	Up-regulation
AGC_Akt_AKT2_ST	Q04656	ATP7A	P31751	AKT2	S1146	S1146Y	1146	Missense	central	0	yes	22.345	0.000	EPSD	COSMIC	19.022	Loss
AGC_Akt_AKT2_ST	Q04656	ATP7A	P31751	AKT2	T1212	K1209R	1209	Missense	distal	-3	no	14.117	21.079	EPSD	COSMIC;GDSC;CCLE	19.022	Gain
AGC_Akt_AKT2_ST	Q04656	ATP7A	P31751	AKT2	S1424	I1426T	1426	Missense	proximal	2	no	26.368	26.015	PhosphoSitePlus;EPSD	COSMIC	19.022	Down-regulation
AGC_Akt_AKT2_ST	Q04656	ATP7A	P31751	AKT2	S1463	R1461K	1461	Missense	proximal	-2	no	28.373	25.308	EPSD;PhosphoSitePlus	COSMIC	19.022	Down-regulation
AGC_Akt_AKT2_ST	Q04656	ATP7A	P31751	AKT2	S1463	N1458S	1458	Missense	distal	-5	no	28.373	28.880	EPSD;PhosphoSitePlus	COSMIC	19.022	Up-regulation
AGC_Akt_AKT2_ST	Q04656	ATP7A	P31751	AKT2	S1463	S1460R	1460	Missense	distal	-3	no	28.373	37.490	EPSD;PhosphoSitePlus	COSMIC	19.022	Up-regulation
AGC_Akt_AKT2_ST	Q04656	ATP7A	P31751	AKT2	S1466	R1461K	1461	Missense	distal	-5	no	28.475	24.808	EPSD;PhosphoSitePlus	COSMIC	19.022	Down-regulation
AGC_Akt_AKT2_ST	Q04656	ATP7A	P31751	AKT2	S1466	S1460R	1460	Missense	distal	-6	no	28.475	28.348	EPSD;PhosphoSitePlus	COSMIC	19.022	Down-regulation
AGC_Akt_AKT2_ST	Q13835	PKP1	P31751	AKT2	S21	D28H	28	Missense	distal	7	no	20.662	20.888	EPSD	COSMIC	19.022	Up-regulation
AGC_Akt_AKT2_ST	Q13835	PKP1	P31751	AKT2	S21	T22M	22	Missense	proximal	1	no	20.662	20.223	EPSD	COSMIC;CCLE	19.022	Down-regulation
AGC_Akt_AKT2_ST	Q13835	PKP1	P31751	AKT2	S142	A140I	140	Missense	proximal	-2	no	24.069	22.531	EPSD	COSMIC	19.022	Down-regulation
AGC_Akt_AKT2_ST	Q13835	PKP1	P31751	AKT2	S188	C190Y	190	Missense	proximal	2	no	27.531	27.220	EPSD;PhosphoSitePlus	COSMIC	19.022	Down-regulation
AGC_Akt_AKT2_ST	Q13835	PKP1	P31751	AKT2	S205	R202G	202	Missense	distal	-3	no	20.966	11.239	EPSD	COSMIC	19.022	Loss
AGC_Akt_AKT2_ST	Q13835	PKP1	P31751	AKT2	S205	R202L	202	Missense	distal	-3	no	20.966	12.869	EPSD	COSMIC;GDSC	19.022	Loss
AGC_Akt_AKT2_ST	Q13835	PKP1	P31751	AKT2	S205	A207V	207	Missense	proximal	2	no	20.966	20.809	EPSD	COSMIC	19.022	Down-regulation
AGC_Akt_AKT2_ST	Q13835	PKP1	P31751	AKT2	S205	P203L	203	Missense	proximal	-2	no	20.966	21.306	EPSD	COSMIC	19.022	Up-regulation
AGC_Akt_AKT2_ST	Q13835	PKP1	P31751	AKT2	T511	S510F	510	Missense	proximal	-1	no	21.951	20.921	EPSD	COSMIC	19.022	Down-regulation
AGC_Akt_AKT2_ST	Q13835	PKP1	P31751	AKT2	T511	A504T	504	Missense	distal	-7	no	21.951	21.896	EPSD	COSMIC;GDSC	19.022	Down-regulation
AGC_Akt_AKT2_ST	Q13835	PKP1	P31751	AKT2	T511	S515N	515	Missense	distal	4	no	21.951	22.098	EPSD	COSMIC	19.022	Up-regulation
AGC_Akt_AKT2_ST	Q13835	PKP1	P31751	AKT2	T511	Y505C	505	Missense	distal	-6	no	21.951	22.153	EPSD	COSMIC;GDSC	19.022	Up-regulation
AGC_Akt_AKT2_ST	Q99683	MAP3K5	P31751	AKT2	S83	G81S	81	Missense	proximal	-2	no	33.303	33.175	PhosphoSitePlus	COSMIC	19.022	Down-regulation
AGC_Akt_AKT2_ST	Q99683	MAP3K5	P31751	AKT2	S83	G87S	87	Missense	distal	4	no	33.303	33.289	PhosphoSitePlus	COSMIC	19.022	Down-regulation
AGC_Akt_AKT2_ST	Q99683	MAP3K5	P31751	AKT2	S461	K458T	458	Missense	distal	-3	no	20.351	14.706	EPSD	COSMIC	19.022	Loss
AGC_Akt_AKT2_ST	Q99683	MAP3K5	P31751	AKT2	S906	S906F	906	Missense	central	0	yes	19.298	0.000	EPSD	COSMIC	19.022	Loss
AGC_Akt_AKT2_ST	Q99683	MAP3K5	P31751	AKT2	S966	V969I	969	Missense	distal	3	no	20.579	21.340	EPSD	COSMIC	19.022	Up-regulation
AGC_Akt_AKT2_ST	Q99683	MAP3K5	P31751	AKT2	T1015	G1012R	1012	Missense	distal	-3	no	11.683	21.411	EPSD	COSMIC	19.022	Gain
AGC_Akt_AKT2_ST	Q99683	MAP3K5	P31751	AKT2	T1059	A1052T	1052	Missense	distal	-7	no	25.919	25.863	EPSD	COSMIC	19.022	Down-regulation
AGC_Akt_AKT2_ST	O43464	HTRA2	P31751	AKT2	S13	G11S	11	Missense	proximal	-2	no	25.953	25.825	EPSD	COSMIC;CCLE	19.022	Down-regulation
AGC_Akt_AKT2_ST	O43464	HTRA2	P31751	AKT2	S41	L39R	39	Missense	proximal	-2	no	19.939	22.389	EPSD	COSMIC	19.022	Up-regulation
AGC_Akt_AKT2_ST	O43464	HTRA2	P31751	AKT2	S44	L39R	39	Missense	distal	-5	no	13.137	20.862	EPSD	COSMIC	19.022	Gain
AGC_Akt_AKT2_ST	O43464	HTRA2	P31751	AKT2	T51	V50G	50	Missense	proximal	-1	no	21.369	20.353	EPSD	COSMIC	19.022	Down-regulation
AGC_Akt_AKT2_ST	O43464	HTRA2	P31751	AKT2	T51	W58C	58	Missense	distal	7	no	21.369	21.566	EPSD	COSMIC	19.022	Up-regulation
AGC_Akt_AKT2_ST	O43464	HTRA2	P31751	AKT2	S96	T101N	101	Missense	distal	5	no	28.776	28.670	EPSD	COSMIC	19.022	Down-regulation
AGC_Akt_AKT2_ST	O43464	HTRA2	P31751	AKT2	S142	S137R	137	Missense	distal	-5	no	15.417	22.577	EPSD	COSMIC	19.022	Gain
AGC_Akt_AKT2_ST	O43464	HTRA2	P31751	AKT2	T242	L240F	240	Missense	proximal	-2	no	22.885	19.693	EPSD	COSMIC	19.022	Down-regulation
AGC_Akt_AKT2_ST	O43464	HTRA2	P31751	AKT2	S400	G399S	399	Missense	proximal	-1	no	18.573	19.341	EPSD	COSMIC	19.022	Gain
AGC_Akt_AKT2_ST	O43464	HTRA2	P31751	AKT2	S435	R442W	442	Missense	distal	7	no	26.851	25.683	EPSD	COSMIC;GDSC;CCLE	19.022	Down-regulation
AGC_Akt_AKT2_ST	O43464	HTRA2	P31751	AKT2	S435	A430G	430	Missense	distal	-5	no	26.851	26.317	EPSD	COSMIC	19.022	Down-regulation
AGC_Akt_AKT2_ST	O43464	HTRA2	P31751	AKT2	S435	A438T	438	Missense	distal	3	no	26.851	26.899	EPSD	COSMIC	19.022	Up-regulation
AGC_Akt_AKT2_ST	P00533	EGFR	P31751	AKT2	S229	R222H	222	Missense	distal	-7	no	28.687	29.266	PhosphoSitePlus	COSMIC	19.022	Up-regulation
AGC_Akt_AKT2_ST	P00533	EGFR	P31751	AKT2	S229	S227Y	227	Missense	proximal	-2	no	28.687	27.603	PhosphoSitePlus	COSMIC	19.022	Down-regulation
AGC_Akt_AKT2_ST	P00533	EGFR	P31751	AKT2	S229	G225C	225	Missense	distal	-4	no	28.687	29.042	PhosphoSitePlus	COSMIC	19.022	Up-regulation
AGC_Akt_AKT2_ST	P00533	EGFR	P31751	AKT2	S229	C231S	231	Missense	proximal	2	no	28.687	27.511	PhosphoSitePlus	COSMIC	19.022	Down-regulation
AGC_Akt_AKT2_ST	P00533	EGFR	P31751	AKT2	S246	R252G	252	Missense	distal	6	no	23.113	21.623	EPSD	COSMIC	19.022	Down-regulation
AGC_Akt_AKT2_ST	P00533	EGFR	P31751	AKT2	S246	C251Y	251	Missense	distal	5	no	23.113	23.932	EPSD	COSMIC;GDSC;CCLE	19.022	Up-regulation
AGC_Akt_AKT2_ST	P00533	EGFR	P31751	AKT2	S246	S246R	246	Missense	central	0	yes	23.113	0.000	EPSD	COSMIC	19.022	Loss
AGC_Akt_AKT2_ST	P00533	EGFR	P31751	AKT2	S246	D247Y	247	Missense	proximal	1	no	23.113	22.761	EPSD	COSMIC	19.022	Down-regulation
AGC_Akt_AKT2_ST	P00533	EGFR	P31751	AKT2	S246	G239C	239	Missense	distal	-7	no	23.113	23.663	EPSD	COSMIC	19.022	Up-regulation
AGC_Akt_AKT2_ST	P00533	EGFR	P31751	AKT2	S246	L249V	249	Missense	distal	3	no	23.113	22.362	EPSD	COSMIC	19.022	Down-regulation
AGC_Akt_AKT2_ST	P00533	EGFR	P31751	AKT2	S246	P243S	243	Missense	distal	-3	no	23.113	20.272	EPSD	COSMIC	19.022	Down-regulation
AGC_Akt_AKT2_ST	P00533	EGFR	P31751	AKT2	S246	P243A	243	Missense	distal	-3	no	23.113	21.414	EPSD	COSMIC	19.022	Down-regulation
AGC_Akt_AKT2_ST	P00533	EGFR	P31751	AKT2	T678	R680Q	680	Missense	proximal	2	no	22.642	23.161	EPSD	COSMIC	19.022	Up-regulation
AGC_Akt_AKT2_ST	P00533	EGFR	P31751	AKT2	T678	V674F	674	Missense	distal	-4	no	22.642	23.140	EPSD	COSMIC	19.022	Up-regulation
AGC_Akt_AKT2_ST	P00533	EGFR	P31751	AKT2	T678	R675Q	675	Missense	distal	-3	no	22.642	13.957	EPSD	COSMIC;GDSC	19.022	Loss
AGC_Akt_AKT2_ST	P00533	EGFR	P31751	AKT2	T678	R680W	680	Missense	proximal	2	no	22.642	24.208	EPSD	COSMIC	19.022	Up-regulation
AGC_Akt_AKT2_ST	P00533	EGFR	P31751	AKT2	T678	H672Y	672	Missense	distal	-6	no	22.642	22.969	EPSD	COSMIC	19.022	Up-regulation
AGC_Akt_AKT2_ST	P00533	EGFR	P31751	AKT2	T678	R680G	680	Missense	proximal	2	no	22.642	22.998	EPSD	COSMIC	19.022	Up-regulation
AGC_Akt_AKT2_ST	P00533	EGFR	P31751	AKT2	T678	K676R	676	Missense	proximal	-2	no	22.642	25.707	EPSD	COSMIC	19.022	Up-regulation
AGC_Akt_AKT2_ST	P00533	EGFR	P31751	AKT2	T678	R671C	671	Missense	distal	-7	no	22.642	23.507	EPSD	COSMIC	19.022	Up-regulation
AGC_Akt_AKT2_ST	P00533	EGFR	P31751	AKT2	T678	R677C	677	Missense	proximal	-1	no	22.642	20.488	EPSD	COSMIC;GDSC;CCLE	19.022	Down-regulation
AGC_Akt_AKT2_ST	P00533	EGFR	P31751	AKT2	T678	R671H	671	Missense	distal	-7	no	22.642	23.221	EPSD	COSMIC	19.022	Up-regulation
AGC_Akt_AKT2_ST	P00533	EGFR	P31751	AKT2	S695	L692P	692	Missense	distal	-3	no	18.385	20.204	EPSD	COSMIC	19.022	Gain
AGC_Akt_AKT2_ST	P00533	EGFR	P31751	AKT2	S695	E690K	690	Missense	distal	-5	no	18.385	21.765	EPSD	COSMIC	19.022	Gain
AGC_Akt_AKT2_ST	P00533	EGFR	P31751	AKT2	S695	E697D	697	Missense	proximal	2	no	18.385	19.551	EPSD	COSMIC	19.022	Gain
AGC_Akt_AKT2_ST	P00533	EGFR	P31751	AKT2	S695	T693A	693	Missense	proximal	-2	no	18.385	20.645	EPSD	COSMIC	19.022	Gain
AGC_Akt_AKT2_ST	P00533	EGFR	P31751	AKT2	T892	Y891D	891	Missense	proximal	-1	no	20.261	19.390	EPSD	COSMIC	19.022	Down-regulation
AGC_Akt_AKT2_ST	P00533	EGFR	P31751	AKT2	T892	L887I	887	Missense	distal	-5	no	20.261	22.263	EPSD	COSMIC	19.022	Up-regulation
AGC_Akt_AKT2_ST	P00533	EGFR	P31751	AKT2	T892	H893R	893	Missense	proximal	1	no	20.261	18.785	EPSD	COSMIC	19.022	Loss
AGC_Akt_AKT2_ST	P00533	EGFR	P31751	AKT2	T892	V897I	897	Missense	distal	5	no	20.261	19.283	EPSD	COSMIC	19.022	Down-regulation
AGC_Akt_AKT2_ST	P00533	EGFR	P31751	AKT2	T892	V897A	897	Missense	distal	5	no	20.261	20.493	EPSD	COSMIC	19.022	Up-regulation
AGC_Akt_AKT2_ST	P00533	EGFR	P31751	AKT2	T892	R889G	889	Missense	distal	-3	no	20.261	10.534	EPSD	COSMIC	19.022	Loss
AGC_Akt_AKT2_ST	P00533	EGFR	P31751	AKT2	S1030	S1025T	1025	Missense	distal	-5	no	20.862	20.762	EPSD	COSMIC	19.022	Down-regulation
AGC_Akt_AKT2_ST	P00533	EGFR	P31751	AKT2	S1030	P1027S	1027	Missense	distal	-3	no	20.862	18.022	EPSD	COSMIC	19.022	Loss
AGC_Akt_AKT2_ST	P00533	EGFR	P31751	AKT2	S1030	S1036R	1036	Missense	distal	6	no	20.862	22.075	EPSD	COSMIC	19.022	Up-regulation
AGC_Akt_AKT2_ST	P00533	EGFR	P31751	AKT2	S1030	S1028L	1028	Missense	proximal	-2	no	20.862	20.993	EPSD	COSMIC	19.022	Up-regulation
AGC_Akt_AKT2_ST	P00533	EGFR	P31751	AKT2	S1030	L1034I	1034	Missense	distal	4	no	20.862	20.899	EPSD	COSMIC	19.022	Up-regulation
AGC_Akt_AKT2_ST	P00533	EGFR	P31751	AKT2	S1039	S1036R	1036	Missense	distal	-3	no	16.966	26.084	EPSD	COSMIC	19.022	Gain
AGC_Akt_AKT2_ST	P00533	EGFR	P31751	AKT2	T1041	S1036R	1036	Missense	distal	-5	no	16.429	23.590	EPSD	COSMIC	19.022	Gain
AGC_Akt_AKT2_ST	P00533	EGFR	P31751	AKT2	S1064	F1065L	1065	Missense	proximal	1	no	19.237	17.753	EPSD	COSMIC	19.022	Loss
AGC_Akt_AKT2_ST	P00533	EGFR	P31751	AKT2	S1064	C1058Y	1058	Missense	distal	-6	no	19.237	19.036	EPSD	COSMIC	19.022	Down-regulation
AGC_Akt_AKT2_ST	P00533	EGFR	P31751	AKT2	S1064	P1059L	1059	Missense	distal	-5	no	19.237	15.610	EPSD	COSMIC	19.022	Loss
AGC_Akt_AKT2_ST	P00533	EGFR	P31751	AKT2	S1064	Q1067L	1067	Missense	distal	3	no	19.237	20.068	EPSD	COSMIC	19.022	Up-regulation
AGC_Akt_AKT2_ST	P00533	EGFR	P31751	AKT2	S1064	Y1069C	1069	Missense	distal	5	no	19.237	18.418	EPSD	COSMIC;GDSC;CCLE	19.022	Loss
AGC_Akt_AKT2_ST	P00533	EGFR	P31751	AKT2	S1064	S1064G	1064	Missense	central	0	yes	19.237	0.000	EPSD	COSMIC	19.022	Loss
AGC_Akt_AKT2_ST	P00533	EGFR	P31751	AKT2	S1064	S1071L	1071	Missense	distal	7	no	19.237	18.608	EPSD	COSMIC	19.022	Loss
AGC_Akt_AKT2_ST	P00533	EGFR	P31751	AKT2	S1064	S1064R	1064	Missense	central	0	yes	19.237	0.000	EPSD	COSMIC	19.022	Loss
AGC_Akt_AKT2_ST	P00533	EGFR	P31751	AKT2	S1064	S1070T	1070	Missense	distal	6	no	19.237	19.195	EPSD	COSMIC	19.022	Down-regulation
AGC_Akt_AKT2_ST	P00533	EGFR	P31751	AKT2	S1064	S1064N	1064	Missense	central	0	yes	19.237	0.000	EPSD	COSMIC	19.022	Loss
AGC_Akt_AKT2_ST	P00533	EGFR	P31751	AKT2	S1120	A1118T	1118	Missense	proximal	-2	no	19.144	16.884	EPSD	COSMIC;GDSC;CCLE	19.022	Loss
AGC_Akt_AKT2_ST	P00533	EGFR	P31751	AKT2	S1120	H1124Q	1124	Missense	distal	4	no	19.144	18.954	EPSD	COSMIC;CCLE	19.022	Loss
AGC_Akt_AKT2_ST	P00533	EGFR	P31751	AKT2	S1120	A1118S	1118	Missense	proximal	-2	no	19.144	17.757	EPSD	COSMIC	19.022	Loss
AGC_Akt_AKT2_ST	P00533	EGFR	P31751	AKT2	S1120	S1120N	1120	Missense	central	0	yes	19.144	0.000	EPSD	COSMIC	19.022	Loss
AGC_Akt_AKT2_ST	P00533	EGFR	P31751	AKT2	S1120	D1127N	1127	Missense	distal	7	no	19.144	19.003	EPSD	COSMIC;GDSC;CCLE	19.022	Loss
AGC_Akt_AKT2_ST	P00533	EGFR	P31751	AKT2	S1204	R1199M	1199	Missense	distal	-5	no	30.072	11.558	EPSD	COSMIC	19.022	Loss
AGC_Akt_AKT2_ST	P00533	EGFR	P31751	AKT2	S1204	S1204R	1204	Missense	central	0	yes	30.072	0.000	EPSD	COSMIC	19.022	Loss
AGC_Akt_AKT2_ST	P00533	EGFR	P31751	AKT2	S1204	A1201T	1201	Missense	distal	-3	no	30.072	25.440	EPSD	COSMIC	19.022	Down-regulation
AGC_Akt_AKT2_ST	P00533	EGFR	P31751	AKT2	S1204	F1207C	1207	Missense	distal	3	no	30.072	29.806	EPSD	COSMIC	19.022	Down-regulation
AGC_Akt_AKT2_ST	P00533	EGFR	P31751	AKT2	S1204	R1199T	1199	Missense	distal	-5	no	30.072	22.811	EPSD	COSMIC	19.022	Down-regulation
AGC_Akt_AKT2_ST	P00533	EGFR	P31751	AKT2	S1204	V1200I	1200	Missense	distal	-4	no	30.072	30.323	EPSD	COSMIC	19.022	Up-regulation
AGC_Akt_AKT2_ST	P15311	EZR	P31751	AKT2	S249	R246K	246	Missense	distal	-3	no	19.336	12.374	EPSD	COSMIC	19.022	Loss
AGC_Akt_AKT2_ST	P15311	EZR	P31751	AKT2	S249	K253R	253	Missense	distal	4	no	19.336	19.169	EPSD	COSMIC;CCLE	19.022	Down-regulation
AGC_Akt_AKT2_ST	P15311	EZR	P31751	AKT2	T299	M305I	305	Missense	distal	6	no	18.874	19.042	EPSD	COSMIC	19.022	Gain
AGC_Akt_AKT2_ST	P15311	EZR	P31751	AKT2	T332	V333M	333	Missense	proximal	1	no	24.052	25.143	EPSD	COSMIC;CCLE	19.022	Up-regulation
AGC_Akt_AKT2_ST	P15311	EZR	P31751	AKT2	T332	V333L	333	Missense	proximal	1	no	24.052	25.437	EPSD	COSMIC	19.022	Up-regulation
AGC_Akt_AKT2_ST	P15311	EZR	P31751	AKT2	T332	E338G	338	Missense	distal	6	no	24.052	23.284	EPSD	COSMIC	19.022	Down-regulation
AGC_Akt_AKT2_ST	P15311	EZR	P31751	AKT2	S413	V408A	408	Missense	distal	-5	no	16.013	19.592	EPSD	COSMIC	19.022	Gain
AGC_Akt_AKT2_ST	P15311	EZR	P31751	AKT2	S535	E537K	537	Missense	proximal	2	no	20.541	20.524	EPSD	COSMIC;CCLE	19.022	Down-regulation
AGC_Akt_AKT2_ST	Q9Y3M2	CBY1	P31751	AKT2	S20	R16Q	16	Missense	distal	-4	no	23.158	23.186	PhosphoSitePlus	COSMIC	19.022	Up-regulation
AGC_Akt_AKT2_ST	Q9Y3M2	CBY1	P31751	AKT2	T63	D70E	70	Missense	distal	7	no	24.969	25.342	EPSD	COSMIC	19.022	Up-regulation
AGC_Akt_AKT2_ST	Q9Y3M2	CBY1	P31751	AKT2	T63	V69M	69	Missense	distal	6	no	24.969	24.014	EPSD	COSMIC	19.022	Down-regulation
AGC_Akt_AKT2_ST	Q9Y3M2	CBY1	P31751	AKT2	T63	G68D	68	Missense	distal	5	no	24.969	24.344	EPSD	COSMIC	19.022	Down-regulation
AGC_Akt_AKT2_ST	P98170	XIAP	P31751	AKT2	S87	R91I	91	Missense	distal	4	no	28.775	29.100	PhosphoSitePlus	COSMIC	19.022	Up-regulation
AGC_Akt_AKT2_ST	P98170	XIAP	P31751	AKT2	S87	P88Q	88	Missense	proximal	1	no	28.775	27.118	PhosphoSitePlus	COSMIC	19.022	Down-regulation
AGC_Akt_AKT2_ST	P98170	XIAP	P31751	AKT2	S261	L256V	256	Missense	distal	-5	no	20.020	18.404	EPSD	COSMIC	19.022	Loss
AGC_Akt_AKT2_ST	P98170	XIAP	P31751	AKT2	S261	N259S	259	Missense	proximal	-2	no	20.020	20.932	EPSD	COSMIC	19.022	Up-regulation
AGC_Akt_AKT2_ST	P98170	XIAP	P31751	AKT2	S436	S430L	430	Missense	distal	-6	no	18.581	19.162	EPSD	COSMIC	19.022	Gain
AGC_Akt_AKT2_ST	Q92908	GATA6	P31751	AKT2	S436	S437P	437	Missense	proximal	1	no	29.593	30.524	EPSD	COSMIC	19.022	Up-regulation
AGC_Akt_AKT2_ST	Q92908	GATA6	P31751	AKT2	S436	R438Q	438	Missense	proximal	2	no	29.593	30.112	EPSD	COSMIC	19.022	Up-regulation
AGC_Akt_AKT2_ST	Q14315	FLNC	P31751	AKT2	T423	Q418H	418	Missense	distal	-5	no	21.423	13.882	EPSD	COSMIC	19.022	Loss
AGC_Akt_AKT2_ST	Q14315	FLNC	P31751	AKT2	S462	T460A	460	Missense	proximal	-2	no	17.871	20.132	EPSD	COSMIC	19.022	Gain
AGC_Akt_AKT2_ST	Q14315	FLNC	P31751	AKT2	S1005	D1000E	1000	Missense	distal	-5	no	8.234	26.497	EPSD	COSMIC	19.022	Gain
AGC_Akt_AKT2_ST	Q14315	FLNC	P31751	AKT2	S1527	Q1522R	1522	Missense	distal	-5	no	16.596	20.930	EPSD	COSMIC	19.022	Gain
AGC_Akt_AKT2_ST	Q14315	FLNC	P31751	AKT2	S1545	G1548S	1548	Missense	distal	3	no	19.413	19.306	EPSD	COSMIC	19.022	Down-regulation
AGC_Akt_AKT2_ST	Q14315	FLNC	P31751	AKT2	S1545	R1543G	1543	Missense	proximal	-2	no	19.413	16.961	EPSD	COSMIC	19.022	Loss
AGC_Akt_AKT2_ST	Q14315	FLNC	P31751	AKT2	S1545	A1544V	1544	Missense	proximal	-1	no	19.413	18.989	EPSD	COSMIC	19.022	Loss
AGC_Akt_AKT2_ST	Q14315	FLNC	P31751	AKT2	S1848	P1849H	1849	Missense	proximal	1	no	23.013	21.995	EPSD	COSMIC	19.022	Down-regulation
AGC_Akt_AKT2_ST	Q14315	FLNC	P31751	AKT2	S1848	N1843H	1843	Missense	distal	-5	no	23.013	18.807	EPSD	COSMIC	19.022	Loss
AGC_Akt_AKT2_ST	Q14315	FLNC	P31751	AKT2	S1848	G1842S	1842	Missense	distal	-6	no	23.013	22.781	EPSD	COSMIC;GDSC;CCLE	19.022	Down-regulation
AGC_Akt_AKT2_ST	Q14315	FLNC	P31751	AKT2	S1848	F1852Y	1852	Missense	distal	4	no	23.013	22.855	EPSD	COSMIC	19.022	Down-regulation
AGC_Akt_AKT2_ST	Q14315	FLNC	P31751	AKT2	S1848	G1847E	1847	Missense	proximal	-1	no	23.013	24.453	EPSD	COSMIC	19.022	Up-regulation
AGC_Akt_AKT2_ST	Q14315	FLNC	P31751	AKT2	S1848	Y1853H	1853	Missense	distal	5	no	23.013	23.622	EPSD	COSMIC	19.022	Up-regulation
AGC_Akt_AKT2_ST	Q14315	FLNC	P31751	AKT2	S1893	G1890R	1890	Missense	distal	-3	no	13.713	23.441	EPSD	COSMIC	19.022	Gain
AGC_Akt_AKT2_ST	Q14315	FLNC	P31751	AKT2	S1940	D1933N	1933	Missense	distal	-7	no	23.719	23.340	EPSD	COSMIC	19.022	Down-regulation
AGC_Akt_AKT2_ST	Q14315	FLNC	P31751	AKT2	S1940	P1938L	1938	Missense	proximal	-2	no	23.719	24.058	EPSD	COSMIC	19.022	Up-regulation
AGC_Akt_AKT2_ST	Q14315	FLNC	P31751	AKT2	S1985	E1988K	1988	Missense	distal	3	no	23.021	22.599	EPSD	COSMIC	19.022	Down-regulation
AGC_Akt_AKT2_ST	Q14315	FLNC	P31751	AKT2	S1985	P1984S	1984	Missense	proximal	-1	no	23.021	23.104	EPSD	COSMIC	19.022	Up-regulation
AGC_Akt_AKT2_ST	Q14315	FLNC	P31751	AKT2	S1985	P1990T	1990	Missense	distal	5	no	23.021	23.599	EPSD	COSMIC	19.022	Up-regulation
AGC_Akt_AKT2_ST	Q14315	FLNC	P31751	AKT2	S1985	P1990S	1990	Missense	distal	5	no	23.021	23.826	EPSD	COSMIC	19.022	Up-regulation
AGC_Akt_AKT2_ST	Q14315	FLNC	P31751	AKT2	S1985	A1979T	1979	Missense	distal	-6	no	23.021	22.950	EPSD	COSMIC	19.022	Down-regulation
AGC_Akt_AKT2_ST	Q14315	FLNC	P31751	AKT2	S1985	E1989K	1989	Missense	distal	4	no	23.021	23.110	EPSD	COSMIC	19.022	Up-regulation
AGC_Akt_AKT2_ST	Q14315	FLNC	P31751	AKT2	S1985	A1979V	1979	Missense	distal	-6	no	23.021	22.892	EPSD	COSMIC	19.022	Down-regulation
AGC_Akt_AKT2_ST	Q14315	FLNC	P31751	AKT2	S2004	I2003N	2003	Missense	proximal	-1	no	20.051	21.051	EPSD	COSMIC	19.022	Up-regulation
AGC_Akt_AKT2_ST	Q14315	FLNC	P31751	AKT2	S2004	G2002V	2002	Missense	proximal	-2	no	20.051	21.787	EPSD	COSMIC	19.022	Up-regulation
AGC_Akt_AKT2_ST	Q14315	FLNC	P31751	AKT2	S2146	R2140H	2140	Missense	distal	-6	no	18.990	19.260	EPSD	COSMIC	19.022	Gain
AGC_Akt_AKT2_ST	Q14315	FLNC	P31751	AKT2	S2146	R2140C	2140	Missense	distal	-6	no	18.990	19.789	EPSD	COSMIC	19.022	Gain
AGC_Akt_AKT2_ST	Q14315	FLNC	P31751	AKT2	S2146	T2153N	2153	Missense	distal	7	no	18.990	19.030	EPSD	COSMIC	19.022	Gain
AGC_Akt_AKT2_ST	Q14315	FLNC	P31751	AKT2	T2179	S2181I	2181	Missense	proximal	2	no	19.607	20.474	EPSD	COSMIC	19.022	Up-regulation
AGC_Akt_AKT2_ST	Q14315	FLNC	P31751	AKT2	T2179	R2176H	2176	Missense	distal	-3	no	19.607	-0.201	EPSD	COSMIC	19.022	Loss
AGC_Akt_AKT2_ST	Q14315	FLNC	P31751	AKT2	T2179	R2173C	2173	Missense	distal	-6	no	19.607	20.406	EPSD	COSMIC;GDSC;CCLE	19.022	Up-regulation
AGC_Akt_AKT2_ST	Q14315	FLNC	P31751	AKT2	T2179	T2177N	2177	Missense	proximal	-2	no	19.607	19.569	EPSD	COSMIC	19.022	Down-regulation
AGC_Akt_AKT2_ST	Q14315	FLNC	P31751	AKT2	S2181	S2181I	2181	Missense	central	0	yes	20.553	0.000	EPSD	COSMIC	19.022	Loss
AGC_Akt_AKT2_ST	Q14315	FLNC	P31751	AKT2	S2181	R2187H	2187	Missense	distal	6	no	20.553	19.270	EPSD	COSMIC;GDSC;CCLE	19.022	Down-regulation
AGC_Akt_AKT2_ST	Q14315	FLNC	P31751	AKT2	S2181	R2176H	2176	Missense	distal	-5	no	20.553	8.678	EPSD	COSMIC	19.022	Loss
AGC_Akt_AKT2_ST	Q14315	FLNC	P31751	AKT2	S2181	T2177N	2177	Missense	distal	-4	no	20.553	20.401	EPSD	COSMIC	19.022	Down-regulation
AGC_Akt_AKT2_ST	Q14315	FLNC	P31751	AKT2	S2233	R2230L	2230	Missense	distal	-3	no	35.073	26.976	PhosphoSitePlus	COSMIC	19.022	Down-regulation
AGC_Akt_AKT2_ST	Q14315	FLNC	P31751	AKT2	S2233	R2239L	2239	Missense	distal	6	no	35.073	33.500	PhosphoSitePlus	COSMIC	19.022	Down-regulation
AGC_Akt_AKT2_ST	Q14315	FLNC	P31751	AKT2	S2395	S2395F	2395	Missense	central	0	yes	19.748	0.000	EPSD	COSMIC	19.022	Loss
AGC_Akt_AKT2_ST	Q14315	FLNC	P31751	AKT2	S2395	V2398M	2398	Missense	distal	3	no	19.748	19.998	EPSD	COSMIC	19.022	Up-regulation
AGC_Akt_AKT2_ST	Q14315	FLNC	P31751	AKT2	S2395	P2400A	2400	Missense	distal	5	no	19.748	20.650	EPSD	COSMIC	19.022	Up-regulation
AGC_Akt_AKT2_ST	Q14315	FLNC	P31751	AKT2	S2395	E2390V	2390	Missense	distal	-5	no	19.748	17.455	EPSD	COSMIC	19.022	Loss
AGC_Akt_AKT2_ST	Q14315	FLNC	P31751	AKT2	T2414	R2410W	2410	Missense	distal	-4	no	18.730	19.445	EPSD	COSMIC	19.022	Gain
AGC_Akt_AKT2_ST	Q14315	FLNC	P31751	AKT2	T2414	G2420R	2420	Missense	distal	6	no	18.730	20.220	EPSD	COSMIC	19.022	Gain
AGC_Akt_AKT2_ST	Q14315	FLNC	P31751	AKT2	S2624	S2619T	2619	Missense	distal	-5	no	21.774	21.674	EPSD	COSMIC	19.022	Down-regulation
AGC_Akt_AKT2_ST	Q14315	FLNC	P31751	AKT2	S2624	Y2625F	2625	Missense	proximal	1	no	21.774	23.391	EPSD	COSMIC	19.022	Up-regulation
AGC_Akt_AKT2_ST	Q14315	FLNC	P31751	AKT2	S2626	S2619T	2619	Missense	distal	-7	no	24.793	24.964	EPSD	COSMIC	19.022	Up-regulation
AGC_Akt_AKT2_ST	Q14315	FLNC	P31751	AKT2	S2626	Y2625F	2625	Missense	proximal	-1	no	24.793	23.901	EPSD	COSMIC	19.022	Down-regulation
AGC_Akt_AKT2_ST	Q14315	FLNC	P31751	AKT2	S2646	F2649S	2649	Missense	distal	3	no	20.213	19.000	EPSD	COSMIC;CCLE	19.022	Loss
AGC_Akt_AKT2_ST	P03372	ESR1	P31751	AKT2	S118	L117Q	117	Missense	proximal	-1	no	18.630	19.789	EPSD	COSMIC	19.022	Gain
AGC_Akt_AKT2_ST	P03372	ESR1	P31751	AKT2	S118	H112L	112	Missense	distal	-6	no	18.630	19.067	EPSD	COSMIC	19.022	Gain
AGC_Akt_AKT2_ST	P03372	ESR1	P31751	AKT2	S167	G172R	172	Missense	distal	5	no	34.641	35.335	PhosphoSitePlus	COSMIC	19.022	Up-regulation
AGC_Akt_AKT2_ST	P03372	ESR1	P31751	AKT2	S167	M174I	174	Missense	distal	7	no	34.641	34.421	PhosphoSitePlus	COSMIC	19.022	Down-regulation
AGC_Akt_AKT2_ST	P03372	ESR1	P31751	AKT2	S167	D170Y	170	Missense	distal	3	no	34.641	34.720	PhosphoSitePlus	COSMIC	19.022	Up-regulation
AGC_Akt_AKT2_ST	P03372	ESR1	P31751	AKT2	S167	G160D	160	Missense	distal	-7	no	34.641	35.051	PhosphoSitePlus	COSMIC	19.022	Up-regulation
AGC_Akt_AKT2_ST	P03372	ESR1	P31751	AKT2	S236	R241G	241	Missense	distal	5	no	31.635	30.941	EPSD	COSMIC	19.022	Down-regulation
AGC_Akt_AKT2_ST	P03372	ESR1	P31751	AKT2	S236	R241W	241	Missense	distal	5	no	31.635	29.847	EPSD	COSMIC	19.022	Down-regulation
AGC_Akt_AKT2_ST	P03372	ESR1	P31751	AKT2	S236	R233G	233	Missense	distal	-3	no	31.635	21.908	EPSD	COSMIC	19.022	Down-regulation
AGC_Akt_AKT2_ST	P03372	ESR1	P31751	AKT2	S236	C237Y	237	Missense	proximal	1	no	31.635	31.025	EPSD	COSMIC	19.022	Down-regulation
AGC_Akt_AKT2_ST	P03372	ESR1	P31751	AKT2	S236	Q238H	238	Missense	proximal	2	no	31.635	31.846	EPSD	COSMIC;CCLE	19.022	Up-regulation
AGC_Akt_AKT2_ST	P03372	ESR1	P31751	AKT2	S236	R243L	243	Missense	distal	7	no	31.635	30.898	EPSD	COSMIC	19.022	Down-regulation
AGC_Akt_AKT2_ST	P03372	ESR1	P31751	AKT2	S282	G276S	276	Missense	distal	-6	no	21.270	21.037	EPSD	COSMIC	19.022	Down-regulation
AGC_Akt_AKT2_ST	P03372	ESR1	P31751	AKT2	S282	G284E	284	Missense	proximal	2	no	21.270	20.899	EPSD	COSMIC	19.022	Down-regulation
AGC_Akt_AKT2_ST	P03372	ESR1	P31751	AKT2	S282	E279V	279	Missense	distal	-3	no	21.270	24.298	EPSD	COSMIC	19.022	Up-regulation
AGC_Akt_AKT2_ST	P03372	ESR1	P31751	AKT2	S282	E275V	275	Missense	distal	-7	no	21.270	21.425	EPSD	COSMIC	19.022	Up-regulation
AGC_Akt_AKT2_ST	P03372	ESR1	P31751	AKT2	S282	G276D	276	Missense	distal	-6	no	21.270	21.562	EPSD	COSMIC;GDSC;CCLE	19.022	Up-regulation
AGC_Akt_AKT2_ST	P03372	ESR1	P31751	AKT2	S282	R277S	277	Missense	distal	-5	no	21.270	14.109	EPSD	COSMIC	19.022	Loss
AGC_Akt_AKT2_ST	P03372	ESR1	P31751	AKT2	S282	S282C	282	Missense	central	0	yes	21.270	0.000	EPSD	COSMIC	19.022	Loss
AGC_Akt_AKT2_ST	P03372	ESR1	P31751	AKT2	S282	A288T	288	Missense	distal	6	no	21.270	20.871	EPSD	COSMIC	19.022	Down-regulation
AGC_Akt_AKT2_ST	P03372	ESR1	P31751	AKT2	S282	R287H	287	Missense	distal	5	no	21.270	20.829	EPSD	COSMIC	19.022	Down-regulation
AGC_Akt_AKT2_ST	P03372	ESR1	P31751	AKT2	S282	R287C	287	Missense	distal	5	no	21.270	19.401	EPSD	COSMIC	19.022	Down-regulation
AGC_Akt_AKT2_ST	P03372	ESR1	P31751	AKT2	S282	G284C	284	Missense	proximal	2	no	21.270	22.411	EPSD	COSMIC	19.022	Up-regulation
AGC_Akt_AKT2_ST	P03372	ESR1	P31751	AKT2	S341	S338R	338	Missense	distal	-3	no	11.662	20.780	EPSD	COSMIC	19.022	Gain
AGC_Akt_AKT2_ST	P03372	ESR1	P31751	AKT2	S554	L549P	549	Missense	distal	-5	no	15.465	19.092	EPSD	COSMIC	19.022	Gain
AGC_Akt_AKT2_ST	Q9H0H5	RACGAP1	P31751	AKT2	S185	T186A	186	Missense	proximal	1	no	24.872	24.770	EPSD	COSMIC	19.022	Down-regulation
AGC_Akt_AKT2_ST	Q9H0H5	RACGAP1	P31751	AKT2	S185	K178N	178	Missense	distal	-7	no	24.872	25.155	EPSD	COSMIC	19.022	Up-regulation
AGC_Akt_AKT2_ST	Q9H0H5	RACGAP1	P31751	AKT2	S185	E181G	181	Missense	distal	-4	no	24.872	25.048	EPSD	COSMIC	19.022	Up-regulation
AGC_Akt_AKT2_ST	Q9H0H5	RACGAP1	P31751	AKT2	S187	T186A	186	Missense	proximal	-1	no	22.931	23.391	EPSD	COSMIC	19.022	Up-regulation
AGC_Akt_AKT2_ST	Q9H0H5	RACGAP1	P31751	AKT2	S187	E181G	181	Missense	distal	-6	no	22.931	23.553	EPSD	COSMIC	19.022	Up-regulation
AGC_Akt_AKT2_ST	Q9H0H5	RACGAP1	P31751	AKT2	T405	R402I	402	Missense	distal	-3	no	26.507	19.102	EPSD	COSMIC	19.022	Down-regulation
AGC_Akt_AKT2_ST	Q9H0H5	RACGAP1	P31751	AKT2	T405	R402T	402	Missense	distal	-3	no	26.507	13.899	EPSD	COSMIC	19.022	Loss
AGC_Akt_AKT2_ST	Q9H0H5	RACGAP1	P31751	AKT2	S592	P589F	589	Missense	distal	-3	no	21.870	10.876	EPSD	COSMIC	19.022	Loss
AGC_Akt_AKT2_ST	Q9H0H5	RACGAP1	P31751	AKT2	S592	R599C	599	Missense	distal	7	no	21.870	20.899	EPSD	COSMIC	19.022	Down-regulation
AGC_Akt_AKT2_ST	Q9H0H5	RACGAP1	P31751	AKT2	S600	R599C	599	Missense	proximal	-1	no	22.113	19.959	EPSD	COSMIC	19.022	Down-regulation
AGC_Akt_AKT2_ST	O43516	WIPF1	P31751	AKT2	S135	G132R	132	Missense	distal	-3	no	23.063	32.790	EPSD	COSMIC;GDSC;CCLE	19.022	Up-regulation
AGC_Akt_AKT2_ST	O43516	WIPF1	P31751	AKT2	T136	G132R	132	Missense	distal	-4	no	19.401	19.027	EPSD	COSMIC;GDSC;CCLE	19.022	Down-regulation
AGC_Akt_AKT2_ST	O43516	WIPF1	P31751	AKT2	S137	G132R	132	Missense	distal	-5	no	22.220	28.514	EPSD	COSMIC;GDSC;CCLE	19.022	Up-regulation
AGC_Akt_AKT2_ST	O43516	WIPF1	P31751	AKT2	S145	V152L	152	Missense	distal	7	no	27.081	26.306	EPSD	COSMIC	19.022	Down-regulation
AGC_Akt_AKT2_ST	O43516	WIPF1	P31751	AKT2	S154	V152L	152	Missense	proximal	-2	no	30.343	28.609	EPSD;PhosphoSitePlus	COSMIC	19.022	Down-regulation
AGC_Akt_AKT2_ST	O43516	WIPF1	P31751	AKT2	S154	R158S	158	Missense	distal	4	no	30.343	30.424	EPSD;PhosphoSitePlus	COSMIC	19.022	Up-regulation
AGC_Akt_AKT2_ST	O43516	WIPF1	P31751	AKT2	S154	P155T	155	Missense	proximal	1	no	30.343	29.664	EPSD;PhosphoSitePlus	COSMIC	19.022	Down-regulation
AGC_Akt_AKT2_ST	O43516	WIPF1	P31751	AKT2	S214	P220L	220	Missense	distal	6	no	21.008	20.833	EPSD	COSMIC	19.022	Down-regulation
AGC_Akt_AKT2_ST	O43516	WIPF1	P31751	AKT2	S296	V294M	294	Missense	proximal	-2	no	23.836	20.970	EPSD	COSMIC	19.022	Down-regulation
AGC_Akt_AKT2_ST	O43516	WIPF1	P31751	AKT2	S296	R299Q	299	Missense	distal	3	no	23.836	23.968	EPSD	COSMIC	19.022	Up-regulation
AGC_Akt_AKT2_ST	O43516	WIPF1	P31751	AKT2	S301	V294M	294	Missense	distal	-7	no	20.577	20.804	EPSD	COSMIC	19.022	Up-regulation
AGC_Akt_AKT2_ST	O43516	WIPF1	P31751	AKT2	S301	R299Q	299	Missense	proximal	-2	no	20.577	18.176	EPSD	COSMIC	19.022	Loss
AGC_Akt_AKT2_ST	O43516	WIPF1	P31751	AKT2	S340	P347T	347	Missense	distal	7	no	22.692	22.507	EPSD	COSMIC	19.022	Down-regulation
AGC_Akt_AKT2_ST	O43516	WIPF1	P31751	AKT2	S340	P346L	346	Missense	distal	6	no	22.692	22.517	EPSD	COSMIC	19.022	Down-regulation
AGC_Akt_AKT2_ST	O43516	WIPF1	P31751	AKT2	S340	S344F	344	Missense	distal	4	no	22.692	23.068	EPSD	COSMIC	19.022	Up-regulation
AGC_Akt_AKT2_ST	O43516	WIPF1	P31751	AKT2	S340	S344P	344	Missense	distal	4	no	22.692	22.971	EPSD	COSMIC;GDSC;CCLE	19.022	Up-regulation
AGC_Akt_AKT2_ST	O43516	WIPF1	P31751	AKT2	S342	P347T	347	Missense	distal	5	no	20.655	21.233	EPSD	COSMIC	19.022	Up-regulation
AGC_Akt_AKT2_ST	O43516	WIPF1	P31751	AKT2	S342	P346L	346	Missense	distal	4	no	20.655	20.583	EPSD	COSMIC	19.022	Down-regulation
AGC_Akt_AKT2_ST	O43516	WIPF1	P31751	AKT2	S342	S344F	344	Missense	proximal	2	no	20.655	21.859	EPSD	COSMIC	19.022	Up-regulation
AGC_Akt_AKT2_ST	O43516	WIPF1	P31751	AKT2	S342	S344P	344	Missense	proximal	2	no	20.655	22.084	EPSD	COSMIC;GDSC;CCLE	19.022	Up-regulation
AGC_Akt_AKT2_ST	O43516	WIPF1	P31751	AKT2	S354	P347T	347	Missense	distal	-7	no	21.719	21.586	EPSD	COSMIC	19.022	Down-regulation
AGC_Akt_AKT2_ST	O43516	WIPF1	P31751	AKT2	S354	P360L	360	Missense	distal	6	no	21.719	21.544	EPSD	COSMIC	19.022	Down-regulation
AGC_Akt_AKT2_ST	O43516	WIPF1	P31751	AKT2	S354	P358L	358	Missense	distal	4	no	21.719	21.648	EPSD	COSMIC	19.022	Down-regulation
AGC_Akt_AKT2_ST	O43516	WIPF1	P31751	AKT2	S392	P399R	399	Missense	distal	7	no	20.440	20.873	EPSD	COSMIC	19.022	Up-regulation
AGC_Akt_AKT2_ST	O43516	WIPF1	P31751	AKT2	S392	G389D	389	Missense	distal	-3	no	20.440	-7.604	EPSD	COSMIC;CCLE	19.022	Loss
AGC_Akt_AKT2_ST	O43516	WIPF1	P31751	AKT2	T398	P399R	399	Missense	proximal	1	no	27.716	25.221	PhosphoSitePlus;EPSD	COSMIC	19.022	Down-regulation
AGC_Akt_AKT2_ST	O43516	WIPF1	P31751	AKT2	S405	S412C	412	Missense	distal	7	no	21.647	20.784	EPSD	COSMIC	19.022	Down-regulation
AGC_Akt_AKT2_ST	O43516	WIPF1	P31751	AKT2	S405	P399R	399	Missense	distal	-6	no	21.647	21.005	EPSD	COSMIC	19.022	Down-regulation
AGC_Akt_AKT2_ST	O43516	WIPF1	P31751	AKT2	S434	T435P	435	Missense	proximal	1	no	19.834	20.513	EPSD	COSMIC	19.022	Up-regulation
AGC_Akt_AKT2_ST	O43516	WIPF1	P31751	AKT2	S434	P432S	432	Missense	proximal	-2	no	19.834	20.042	EPSD	COSMIC	19.022	Up-regulation
AGC_Akt_AKT2_ST	O43516	WIPF1	P31751	AKT2	S434	G440S	440	Missense	distal	6	no	19.834	20.111	EPSD	COSMIC	19.022	Up-regulation
AGC_Akt_AKT2_ST	O43516	WIPF1	P31751	AKT2	T435	T435P	435	Missense	central	0	yes	24.674	0.000	EPSD	COSMIC	19.022	Loss
AGC_Akt_AKT2_ST	O43516	WIPF1	P31751	AKT2	T435	P432S	432	Missense	distal	-3	no	24.674	21.834	EPSD	COSMIC	19.022	Down-regulation
AGC_Akt_AKT2_ST	O43516	WIPF1	P31751	AKT2	T435	G440S	440	Missense	distal	5	no	24.674	25.019	EPSD	COSMIC	19.022	Up-regulation
AGC_Akt_AKT2_ST	O43516	WIPF1	P31751	AKT2	S488	R485L	485	Missense	distal	-3	no	24.005	15.908	EPSD	COSMIC	19.022	Loss
AGC_Akt_AKT2_ST	O43516	WIPF1	P31751	AKT2	S488	R485Q	485	Missense	distal	-3	no	24.005	15.320	EPSD	COSMIC	19.022	Loss
AGC_Akt_AKT2_ST	O43516	WIPF1	P31751	AKT2	S488	G487E	487	Missense	proximal	-1	no	24.005	25.445	EPSD	COSMIC	19.022	Up-regulation
AGC_Akt_AKT2_ST	Q96F86	EDC3	P31751	AKT2	S161	R167K	167	Missense	distal	6	no	34.291	33.357	PhosphoSitePlus	COSMIC	19.022	Down-regulation
AGC_Akt_AKT2_ST	Q96F86	EDC3	P31751	AKT2	S161	R157C	157	Missense	distal	-4	no	34.291	35.020	PhosphoSitePlus	COSMIC	19.022	Up-regulation
AGC_Akt_AKT2_ST	Q99623	PHB2	P31751	AKT2	T169	R166W	166	Missense	distal	-3	no	19.307	3.579	EPSD	COSMIC;CCLE	19.022	Loss
AGC_Akt_AKT2_ST	Q99623	PHB2	P31751	AKT2	T169	R165C	165	Missense	distal	-4	no	19.307	20.036	EPSD	COSMIC	19.022	Up-regulation
AGC_Akt_AKT2_ST	Q99623	PHB2	P31751	AKT2	T263	N269T	269	Missense	distal	6	no	19.475	19.455	EPSD	COSMIC	19.022	Down-regulation
AGC_Akt_AKT2_ST	Q99623	PHB2	P31751	AKT2	T263	Q258E	258	Missense	distal	-5	no	19.475	16.761	EPSD	COSMIC	19.022	Loss
AGC_Akt_AKT2_ST	Q92945	KHSRP	P31751	AKT2	S193	S193C	193	Missense	central	0	yes	28.142	0.000	PhosphoSitePlus	COSMIC;CCLE	19.022	Loss
AGC_Akt_AKT2_ST	Q92945	KHSRP	P31751	AKT2	S670	G663D	663	Missense	distal	-7	no	21.412	21.822	EPSD	COSMIC	19.022	Up-regulation
AGC_Akt_AKT2_ST	O60331	PIP5K1C	P31751	AKT2	S355	A352V	352	Missense	distal	-3	no	20.070	15.604	EPSD	COSMIC;GDSC;CCLE	19.022	Loss
AGC_Akt_AKT2_ST	O60331	PIP5K1C	P31751	AKT2	S355	A352T	352	Missense	distal	-3	no	20.070	15.438	EPSD	COSMIC	19.022	Loss
AGC_Akt_AKT2_ST	O60331	PIP5K1C	P31751	AKT2	S539	R538L	538	Missense	proximal	-1	no	21.962	20.325	EPSD	COSMIC	19.022	Down-regulation
AGC_Akt_AKT2_ST	O60331	PIP5K1C	P31751	AKT2	S539	S532P	532	Missense	distal	-7	no	21.962	22.267	EPSD	COSMIC;GDSC;CCLE	19.022	Up-regulation
AGC_Akt_AKT2_ST	O60331	PIP5K1C	P31751	AKT2	S541	R538L	538	Missense	distal	-3	no	25.896	17.799	EPSD	COSMIC	19.022	Loss
AGC_Akt_AKT2_ST	O60331	PIP5K1C	P31751	AKT2	T543	R538L	538	Missense	distal	-5	no	22.618	14.893	EPSD	COSMIC	19.022	Loss
AGC_Akt_AKT2_ST	O60331	PIP5K1C	P31751	AKT2	T553	R552G	552	Missense	proximal	-1	no	28.809	27.076	EPSD	COSMIC	19.022	Down-regulation
AGC_Akt_AKT2_ST	O60331	PIP5K1C	P31751	AKT2	T553	R552C	552	Missense	proximal	-1	no	28.809	26.655	EPSD	COSMIC;GDSC;CCLE	19.022	Down-regulation
AGC_Akt_AKT2_ST	O60331	PIP5K1C	P31751	AKT2	T553	R552L	552	Missense	proximal	-1	no	28.809	27.172	EPSD	COSMIC	19.022	Down-regulation
AGC_Akt_AKT2_ST	O60331	PIP5K1C	P31751	AKT2	S555	R552G	552	Missense	distal	-3	no	30.031	20.303	PhosphoSitePlus	COSMIC	19.022	Down-regulation
AGC_Akt_AKT2_ST	O60331	PIP5K1C	P31751	AKT2	S555	R552C	552	Missense	distal	-3	no	30.031	-3.978	PhosphoSitePlus	COSMIC;GDSC;CCLE	19.022	Loss
AGC_Akt_AKT2_ST	O60331	PIP5K1C	P31751	AKT2	S555	R552L	552	Missense	distal	-3	no	30.031	21.934	PhosphoSitePlus	COSMIC	19.022	Down-regulation
AGC_Akt_AKT2_ST	O60331	PIP5K1C	P31751	AKT2	S556	R552C	552	Missense	distal	-4	no	18.471	19.200	EPSD	COSMIC;GDSC;CCLE	19.022	Gain
AGC_Akt_AKT2_ST	O60331	PIP5K1C	P31751	AKT2	S650	L652F	652	Missense	proximal	2	no	19.210	19.456	EPSD	COSMIC;CCLE	19.022	Up-regulation
AGC_Akt_AKT2_ST	O60331	PIP5K1C	P31751	AKT2	S650	H653P	653	Missense	distal	3	no	19.210	19.381	EPSD	COSMIC	19.022	Up-regulation
AGC_Akt_AKT2_ST	O15111	CHUK	P31751	AKT2	T23	E16V	16	Missense	distal	-7	no	34.368	34.524	PhosphoSitePlus	COSMIC	19.022	Up-regulation
AGC_Akt_AKT2_ST	O15111	CHUK	P31751	AKT2	T23	M17T	17	Missense	distal	-6	no	34.368	34.065	PhosphoSitePlus	COSMIC	19.022	Down-regulation
AGC_Akt_AKT2_ST	O15111	CHUK	P31751	AKT2	T179	S180F	180	Missense	proximal	1	no	19.148	20.738	EPSD	COSMIC	19.022	Up-regulation
AGC_Akt_AKT2_ST	O15111	CHUK	P31751	AKT2	T593	T593I	593	Missense	central	0	yes	20.968	0.000	EPSD	COSMIC	19.022	Loss
AGC_Akt_AKT2_ST	P35222	CTNNB1	P31751	AKT2	S23	Q28E	28	Missense	distal	5	no	38.040	38.314	EPSD	COSMIC	19.022	Up-regulation
AGC_Akt_AKT2_ST	P35222	CTNNB1	P31751	AKT2	S23	A21V	21	Missense	proximal	-2	no	38.040	38.517	EPSD	COSMIC	19.022	Up-regulation
AGC_Akt_AKT2_ST	P35222	CTNNB1	P31751	AKT2	S23	A21T	21	Missense	proximal	-2	no	38.040	35.779	EPSD	COSMIC	19.022	Down-regulation
AGC_Akt_AKT2_ST	P35222	CTNNB1	P31751	AKT2	S23	V22I	22	Missense	proximal	-1	no	38.040	37.103	EPSD	COSMIC	19.022	Down-regulation
AGC_Akt_AKT2_ST	P35222	CTNNB1	P31751	AKT2	S23	S29P	29	Missense	distal	6	no	38.040	37.855	EPSD	COSMIC	19.022	Down-regulation
AGC_Akt_AKT2_ST	P35222	CTNNB1	P31751	AKT2	S23	A20V	20	Missense	distal	-3	no	38.040	33.574	EPSD	COSMIC	19.022	Down-regulation
AGC_Akt_AKT2_ST	P35222	CTNNB1	P31751	AKT2	S23	P16T	16	Missense	distal	-7	no	38.040	37.907	EPSD	COSMIC	19.022	Down-regulation
AGC_Akt_AKT2_ST	P35222	CTNNB1	P31751	AKT2	S23	D17H	17	Missense	distal	-6	no	38.040	37.659	EPSD	COSMIC	19.022	Down-regulation
AGC_Akt_AKT2_ST	P35222	CTNNB1	P31751	AKT2	S23	Q27H	27	Missense	distal	4	no	38.040	38.231	EPSD	COSMIC	19.022	Up-regulation
AGC_Akt_AKT2_ST	P35222	CTNNB1	P31751	AKT2	S23	S23N	23	Missense	central	0	yes	38.040	0.000	EPSD	COSMIC	19.022	Loss
AGC_Akt_AKT2_ST	P35222	CTNNB1	P31751	AKT2	S23	S29F	29	Missense	distal	6	no	38.040	37.071	EPSD	COSMIC	19.022	Down-regulation
AGC_Akt_AKT2_ST	P35222	CTNNB1	P31751	AKT2	S23	Y30C	30	Missense	distal	7	no	38.040	37.602	EPSD	COSMIC	19.022	Down-regulation
AGC_Akt_AKT2_ST	P35222	CTNNB1	P31751	AKT2	S23	S29Y	29	Missense	distal	6	no	38.040	37.701	EPSD	COSMIC	19.022	Down-regulation
AGC_Akt_AKT2_ST	P35222	CTNNB1	P31751	AKT2	S23	S23R	23	Missense	central	0	yes	38.040	0.000	EPSD	COSMIC	19.022	Loss
AGC_Akt_AKT2_ST	P35222	CTNNB1	P31751	AKT2	S23	H24Y	24	Missense	proximal	1	no	38.040	38.102	EPSD	COSMIC	19.022	Up-regulation
AGC_Akt_AKT2_ST	P35222	CTNNB1	P31751	AKT2	S23	W25R	25	Missense	proximal	2	no	38.040	36.474	EPSD	COSMIC	19.022	Down-regulation
AGC_Akt_AKT2_ST	P35222	CTNNB1	P31751	AKT2	S23	V22A	22	Missense	proximal	-1	no	38.040	38.465	EPSD	COSMIC	19.022	Up-regulation
AGC_Akt_AKT2_ST	P35222	CTNNB1	P31751	AKT2	S23	W25L	25	Missense	proximal	2	no	38.040	37.753	EPSD	COSMIC	19.022	Down-regulation
AGC_Akt_AKT2_ST	P35222	CTNNB1	P31751	AKT2	S23	H24Q	24	Missense	proximal	1	no	38.040	37.402	EPSD	COSMIC	19.022	Down-regulation
AGC_Akt_AKT2_ST	P35222	CTNNB1	P31751	AKT2	S23	S23G	23	Missense	central	0	yes	38.040	0.000	EPSD	COSMIC	19.022	Loss
AGC_Akt_AKT2_ST	P35222	CTNNB1	P31751	AKT2	S23	V22G	22	Missense	proximal	-1	no	38.040	37.024	EPSD	COSMIC	19.022	Down-regulation
AGC_Akt_AKT2_ST	P35222	CTNNB1	P31751	AKT2	S23	S29A	29	Missense	distal	6	no	38.040	38.397	EPSD	COSMIC	19.022	Up-regulation
AGC_Akt_AKT2_ST	P35222	CTNNB1	P31751	AKT2	S23	D17Y	17	Missense	distal	-6	no	38.040	37.986	EPSD	COSMIC	19.022	Down-regulation
AGC_Akt_AKT2_ST	P35222	CTNNB1	P31751	AKT2	S23	A21D	21	Missense	proximal	-2	no	38.040	33.827	EPSD	COSMIC	19.022	Down-regulation
AGC_Akt_AKT2_ST	P35222	CTNNB1	P31751	AKT2	S23	P16L	16	Missense	distal	-7	no	38.040	38.144	EPSD	COSMIC	19.022	Up-regulation
AGC_Akt_AKT2_ST	P35222	CTNNB1	P31751	AKT2	S23	Y30S	30	Missense	distal	7	no	38.040	38.465	EPSD	COSMIC	19.022	Up-regulation
AGC_Akt_AKT2_ST	P35222	CTNNB1	P31751	AKT2	S23	H24R	24	Missense	proximal	1	no	38.040	36.564	EPSD	COSMIC	19.022	Down-regulation
AGC_Akt_AKT2_ST	P35222	CTNNB1	P31751	AKT2	S23	Q26R	26	Missense	distal	3	no	38.040	37.908	EPSD	COSMIC;GDSC;CCLE	19.022	Down-regulation
AGC_Akt_AKT2_ST	P35222	CTNNB1	P31751	AKT2	S23	R18K	18	Missense	distal	-5	no	38.040	34.373	EPSD	COSMIC	19.022	Down-regulation
AGC_Akt_AKT2_ST	P35222	CTNNB1	P31751	AKT2	S23	Q28R	28	Missense	distal	5	no	38.040	38.050	EPSD	COSMIC	19.022	Up-regulation
AGC_Akt_AKT2_ST	P35222	CTNNB1	P31751	AKT2	S23	P16S	16	Missense	distal	-7	no	38.040	37.735	EPSD	COSMIC	19.022	Down-regulation
AGC_Akt_AKT2_ST	P35222	CTNNB1	P31751	AKT2	S23	A20T	20	Missense	distal	-3	no	38.040	33.408	EPSD	COSMIC	19.022	Down-regulation
AGC_Akt_AKT2_ST	P35222	CTNNB1	P31751	AKT2	S23	S29T	29	Missense	distal	6	no	38.040	37.998	EPSD	COSMIC	19.022	Down-regulation
AGC_Akt_AKT2_ST	P35222	CTNNB1	P31751	AKT2	S23	K19D	19	Missense	distal	-4	no	38.040	38.513	EPSD	COSMIC	19.022	Up-regulation
AGC_Akt_AKT2_ST	P35222	CTNNB1	P31751	AKT2	S29	H24R	24	Missense	distal	-5	no	8.490	20.365	EPSD	COSMIC	19.022	Gain
AGC_Akt_AKT2_ST	P35222	CTNNB1	P31751	AKT2	T42	T40A	40	Missense	proximal	-2	no	18.061	20.322	EPSD	COSMIC	19.022	Gain
AGC_Akt_AKT2_ST	P35222	CTNNB1	P31751	AKT2	T42	G48V	48	Missense	distal	6	no	18.061	19.031	EPSD	COSMIC	19.022	Gain
AGC_Akt_AKT2_ST	P35222	CTNNB1	P31751	AKT2	S129	Q130H	130	Missense	proximal	1	no	22.753	23.391	EPSD	COSMIC	19.022	Up-regulation
AGC_Akt_AKT2_ST	P35222	CTNNB1	P31751	AKT2	S129	P128L	128	Missense	proximal	-1	no	22.753	22.165	EPSD	COSMIC	19.022	Down-regulation
AGC_Akt_AKT2_ST	P35222	CTNNB1	P31751	AKT2	S129	K133M	133	Missense	distal	4	no	22.753	22.801	EPSD	COSMIC	19.022	Up-regulation
AGC_Akt_AKT2_ST	P35222	CTNNB1	P31751	AKT2	S129	V122G	122	Missense	distal	-7	no	22.753	22.787	EPSD	COSMIC	19.022	Up-regulation
AGC_Akt_AKT2_ST	P35222	CTNNB1	P31751	AKT2	T217	T214A	214	Missense	distal	-3	no	22.100	26.732	EPSD	COSMIC	19.022	Up-regulation
AGC_Akt_AKT2_ST	P35222	CTNNB1	P31751	AKT2	T217	R212C	212	Missense	distal	-5	no	22.100	-1.723	EPSD	COSMIC	19.022	Loss
AGC_Akt_AKT2_ST	P35222	CTNNB1	P31751	AKT2	T217	A211T	211	Missense	distal	-6	no	22.100	22.028	EPSD	COSMIC	19.022	Down-regulation
AGC_Akt_AKT2_ST	P35222	CTNNB1	P31751	AKT2	T332	V325I	325	Missense	distal	-7	no	18.835	19.325	EPSD	COSMIC	19.022	Gain
AGC_Akt_AKT2_ST	P35222	CTNNB1	P31751	AKT2	T332	K335R	335	Missense	distal	3	no	18.835	19.236	EPSD	COSMIC	19.022	Gain
AGC_Akt_AKT2_ST	P35222	CTNNB1	P31751	AKT2	T332	K335Q	335	Missense	distal	3	no	18.835	19.367	EPSD	COSMIC	19.022	Gain
AGC_Akt_AKT2_ST	P35222	CTNNB1	P31751	AKT2	T332	L337P	337	Missense	distal	5	no	18.835	19.391	EPSD	COSMIC	19.022	Gain
AGC_Akt_AKT2_ST	P35222	CTNNB1	P31751	AKT2	T472	E479K	479	Missense	distal	7	no	26.305	26.015	EPSD	COSMIC	19.022	Down-regulation
AGC_Akt_AKT2_ST	P35222	CTNNB1	P31751	AKT2	T472	L468V	468	Missense	distal	-4	no	26.305	25.953	EPSD	COSMIC	19.022	Down-regulation
AGC_Akt_AKT2_ST	P35222	CTNNB1	P31751	AKT2	T472	A478T	478	Missense	distal	6	no	26.305	25.907	EPSD	COSMIC	19.022	Down-regulation
AGC_Akt_AKT2_ST	P35222	CTNNB1	P31751	AKT2	T472	H475Q	475	Missense	distal	3	no	26.305	25.761	EPSD	COSMIC	19.022	Down-regulation
AGC_Akt_AKT2_ST	P35222	CTNNB1	P31751	AKT2	T472	L471Q	471	Missense	proximal	-1	no	26.305	27.464	EPSD	COSMIC	19.022	Up-regulation
AGC_Akt_AKT2_ST	P35222	CTNNB1	P31751	AKT2	T472	R469C	469	Missense	distal	-3	no	26.305	-7.704	EPSD	COSMIC	19.022	Loss
AGC_Akt_AKT2_ST	P35222	CTNNB1	P31751	AKT2	T472	A478G	478	Missense	distal	6	no	26.305	25.672	EPSD	COSMIC	19.022	Down-regulation
AGC_Akt_AKT2_ST	P35222	CTNNB1	P31751	AKT2	S552	T551K	551	Missense	proximal	-1	no	30.281	30.034	PhosphoSitePlus	COSMIC	19.022	Down-regulation
AGC_Akt_AKT2_ST	P35222	CTNNB1	P31751	AKT2	S552	R549C	549	Missense	distal	-3	no	30.281	-3.728	PhosphoSitePlus	COSMIC	19.022	Loss
AGC_Akt_AKT2_ST	P35222	CTNNB1	P31751	AKT2	S552	Q545K	545	Missense	distal	-7	no	30.281	30.246	PhosphoSitePlus	COSMIC	19.022	Down-regulation
AGC_Akt_AKT2_ST	P35222	CTNNB1	P31751	AKT2	S552	Q558H	558	Missense	distal	6	no	30.281	29.786	PhosphoSitePlus	COSMIC	19.022	Down-regulation
AGC_Akt_AKT2_ST	P35222	CTNNB1	P31751	AKT2	S552	G555A	555	Missense	distal	3	no	30.281	30.667	PhosphoSitePlus	COSMIC	19.022	Up-regulation
AGC_Akt_AKT2_ST	P35222	CTNNB1	P31751	AKT2	S552	R550H	550	Missense	proximal	-2	no	30.281	27.383	PhosphoSitePlus	COSMIC	19.022	Down-regulation
AGC_Akt_AKT2_ST	P35222	CTNNB1	P31751	AKT2	S552	R550L	550	Missense	proximal	-2	no	30.281	27.831	PhosphoSitePlus	COSMIC	19.022	Down-regulation
AGC_Akt_AKT2_ST	P35222	CTNNB1	P31751	AKT2	S552	D546E	546	Missense	distal	-6	no	30.281	29.367	PhosphoSitePlus	COSMIC	19.022	Down-regulation
AGC_Akt_AKT2_ST	P35222	CTNNB1	P31751	AKT2	S552	S552F	552	Missense	central	0	yes	30.281	0.000	PhosphoSitePlus	COSMIC	19.022	Loss
AGC_Akt_AKT2_ST	P35222	CTNNB1	P31751	AKT2	S552	T547S	547	Missense	distal	-5	no	30.281	30.381	PhosphoSitePlus	COSMIC	19.022	Up-regulation
AGC_Akt_AKT2_ST	P35222	CTNNB1	P31751	AKT2	S552	G554D	554	Missense	proximal	2	no	30.281	31.077	PhosphoSitePlus	COSMIC	19.022	Up-regulation
AGC_Akt_AKT2_ST	P35222	CTNNB1	P31751	AKT2	S552	R550Q	550	Missense	proximal	-2	no	30.281	27.881	PhosphoSitePlus	COSMIC	19.022	Down-regulation
AGC_Akt_AKT2_ST	P35222	CTNNB1	P31751	AKT2	S552	T551I	551	Missense	proximal	-1	no	30.281	29.381	PhosphoSitePlus	COSMIC	19.022	Down-regulation
AGC_Akt_AKT2_ST	P35222	CTNNB1	P31751	AKT2	T641	L640R	640	Missense	proximal	-1	no	18.496	20.134	EPSD	COSMIC	19.022	Gain
AGC_Akt_AKT2_ST	P35222	CTNNB1	P31751	AKT2	T641	L640Q	640	Missense	proximal	-1	no	18.496	19.654	EPSD	COSMIC	19.022	Gain
AGC_Akt_AKT2_ST	P35222	CTNNB1	P31751	AKT2	S646	T653R	653	Missense	distal	7	no	18.477	19.095	EPSD	COSMIC	19.022	Gain
AGC_Akt_AKT2_ST	P35222	CTNNB1	P31751	AKT2	S646	R647G	647	Missense	proximal	1	no	18.477	20.272	EPSD	COSMIC	19.022	Gain
AGC_Akt_AKT2_ST	P35222	CTNNB1	P31751	AKT2	S646	L643P	643	Missense	distal	-3	no	18.477	20.297	EPSD	COSMIC	19.022	Gain
AGC_Akt_AKT2_ST	Q9GZV1	ANKRD2	P31751	AKT2	S99	R94C	94	Missense	distal	-5	no	31.516	7.694	PhosphoSitePlus	COSMIC;GDSC;CCLE	19.022	Loss
AGC_Akt_AKT2_ST	Q9GZV1	ANKRD2	P31751	AKT2	S99	V95M	95	Missense	distal	-4	no	31.516	31.812	PhosphoSitePlus	COSMIC	19.022	Up-regulation
AGC_Akt_AKT2_ST	Q9GZV1	ANKRD2	P31751	AKT2	S99	K97R	97	Missense	proximal	-2	no	31.516	34.581	PhosphoSitePlus	COSMIC	19.022	Up-regulation
AGC_Akt_AKT2_ST	Q9GZV1	ANKRD2	P31751	AKT2	S99	R104W	104	Missense	distal	5	no	31.516	29.728	PhosphoSitePlus	COSMIC	19.022	Down-regulation
AGC_Akt_AKT2_ST	Q9GZV1	ANKRD2	P31751	AKT2	S99	R103Q	103	Missense	distal	4	no	31.516	31.555	PhosphoSitePlus	COSMIC	19.022	Up-regulation
AGC_Akt_AKT2_ST	Q9GZV1	ANKRD2	P31751	AKT2	S99	R96H	96	Missense	distal	-3	no	31.516	11.707	PhosphoSitePlus	COSMIC	19.022	Loss
AGC_Akt_AKT2_ST	Q9GZV1	ANKRD2	P31751	AKT2	S99	E93G	93	Missense	distal	-6	no	31.516	32.139	PhosphoSitePlus	COSMIC	19.022	Up-regulation
AGC_Akt_AKT2_ST	Q86YS7	C2CD5	P31751	AKT2	S197	I196T	196	Missense	proximal	-1	no	34.053	34.953	PhosphoSitePlus	COSMIC	19.022	Up-regulation
AGC_Akt_AKT2_ST	Q86YS7	C2CD5	P31751	AKT2	S197	M199T	199	Missense	proximal	2	no	34.053	34.132	PhosphoSitePlus	COSMIC	19.022	Up-regulation
AGC_Akt_AKT2_ST	Q86YS7	C2CD5	P31751	AKT2	S250	L248S	248	Missense	proximal	-2	no	24.085	23.955	EPSD	COSMIC	19.022	Down-regulation
AGC_Akt_AKT2_ST	Q86YS7	C2CD5	P31751	AKT2	S262	E264K	264	Missense	proximal	2	no	19.614	19.597	EPSD	COSMIC	19.022	Down-regulation
AGC_Akt_AKT2_ST	Q86YS7	C2CD5	P31751	AKT2	S262	M265K	265	Missense	distal	3	no	19.614	18.751	EPSD	COSMIC	19.022	Loss
AGC_Akt_AKT2_ST	Q86YS7	C2CD5	P31751	AKT2	S262	S260F	260	Missense	proximal	-2	no	19.614	16.553	EPSD	COSMIC	19.022	Loss
AGC_Akt_AKT2_ST	Q86YS7	C2CD5	P31751	AKT2	S301	F294L	294	Missense	distal	-7	no	19.998	19.758	EPSD	COSMIC	19.022	Down-regulation
AGC_Akt_AKT2_ST	Q86YS7	C2CD5	P31751	AKT2	S341	Q340E	340	Missense	proximal	-1	no	22.500	22.686	EPSD	COSMIC	19.022	Up-regulation
AGC_Akt_AKT2_ST	Q86YS7	C2CD5	P31751	AKT2	T601	S606P	606	Missense	distal	5	no	20.186	19.381	EPSD	COSMIC	19.022	Down-regulation
AGC_Akt_AKT2_ST	Q86YS7	C2CD5	P31751	AKT2	T601	D604H	604	Missense	distal	3	no	20.186	20.047	EPSD	COSMIC	19.022	Down-regulation
AGC_Akt_AKT2_ST	Q86YS7	C2CD5	P31751	AKT2	S652	P646L	646	Missense	distal	-6	no	19.835	19.901	EPSD	COSMIC	19.022	Up-regulation
AGC_Akt_AKT2_ST	Q86YS7	C2CD5	P31751	AKT2	S652	R651C	651	Missense	proximal	-1	no	19.835	17.681	EPSD	COSMIC	19.022	Loss
AGC_Akt_AKT2_ST	Q86YS7	C2CD5	P31751	AKT2	S652	L655V	655	Missense	distal	3	no	19.835	19.085	EPSD	COSMIC	19.022	Down-regulation
AGC_Akt_AKT2_ST	Q86YS7	C2CD5	P31751	AKT2	S652	R653C	653	Missense	proximal	1	no	19.835	21.984	EPSD	COSMIC	19.022	Up-regulation
AGC_Akt_AKT2_ST	Q86YS7	C2CD5	P31751	AKT2	S657	L655V	655	Missense	proximal	-2	no	17.687	19.421	EPSD	COSMIC	19.022	Gain
AGC_Akt_AKT2_ST	Q86YS7	C2CD5	P31751	AKT2	S659	S662T	662	Missense	distal	3	no	27.898	28.440	EPSD	COSMIC	19.022	Up-regulation
AGC_Akt_AKT2_ST	Q86YS7	C2CD5	P31751	AKT2	S659	L655V	655	Missense	distal	-4	no	27.898	27.546	EPSD	COSMIC	19.022	Down-regulation
AGC_Akt_AKT2_ST	Q86YS7	C2CD5	P31751	AKT2	S659	R653C	653	Missense	distal	-6	no	27.898	28.697	EPSD	COSMIC	19.022	Up-regulation
AGC_Akt_AKT2_ST	Q86YS7	C2CD5	P31751	AKT2	S661	L668V	668	Missense	distal	7	no	21.590	22.365	EPSD	COSMIC	19.022	Up-regulation
AGC_Akt_AKT2_ST	Q86YS7	C2CD5	P31751	AKT2	S661	S662T	662	Missense	proximal	1	no	21.590	21.842	EPSD	COSMIC	19.022	Up-regulation
AGC_Akt_AKT2_ST	Q86YS7	C2CD5	P31751	AKT2	S661	L655V	655	Missense	distal	-6	no	21.590	21.018	EPSD	COSMIC	19.022	Down-regulation
AGC_Akt_AKT2_ST	Q86YS7	C2CD5	P31751	AKT2	S863	R860W	860	Missense	distal	-3	no	22.335	6.607	EPSD	COSMIC;GDSC;CCLE	19.022	Loss
AGC_Akt_AKT2_ST	Q7Z6J0	SH3RF1	P31751	AKT2	S125	G118V	118	Missense	distal	-7	no	29.209	29.175	EPSD	COSMIC	19.022	Down-regulation
AGC_Akt_AKT2_ST	Q7Z6J0	SH3RF1	P31751	AKT2	S125	G118R	118	Missense	distal	-7	no	29.209	28.894	EPSD	COSMIC	19.022	Down-regulation
AGC_Akt_AKT2_ST	Q7Z6J0	SH3RF1	P31751	AKT2	S304	K300N	300	Missense	distal	-4	no	27.123	27.036	PhosphoSitePlus	COSMIC	19.022	Down-regulation
AGC_Akt_AKT2_ST	Q7Z6J0	SH3RF1	P31751	AKT2	T509	P503S	503	Missense	distal	-6	no	25.931	25.416	EPSD	COSMIC	19.022	Down-regulation
AGC_Akt_AKT2_ST	Q7Z6J0	SH3RF1	P31751	AKT2	T529	P533L	533	Missense	distal	4	no	19.448	19.377	EPSD	COSMIC	19.022	Down-regulation
AGC_Akt_AKT2_ST	Q7Z6J0	SH3RF1	P31751	AKT2	T529	R526W	526	Missense	distal	-3	no	19.448	3.720	EPSD	COSMIC	19.022	Loss
AGC_Akt_AKT2_ST	Q7Z6J0	SH3RF1	P31751	AKT2	T684	P678L	678	Missense	distal	-6	no	20.214	20.279	EPSD	COSMIC	19.022	Up-regulation
AGC_Akt_AKT2_ST	Q7Z6J0	SH3RF1	P31751	AKT2	T684	L686F	686	Missense	proximal	2	no	20.214	20.460	EPSD	COSMIC	19.022	Up-regulation
AGC_Akt_AKT2_ST	Q7Z6J0	SH3RF1	P31751	AKT2	S692	L686F	686	Missense	distal	-6	no	23.212	23.371	EPSD	COSMIC	19.022	Up-regulation
AGC_Akt_AKT2_ST	Q7Z6J0	SH3RF1	P31751	AKT2	S692	D694N	694	Missense	proximal	2	no	23.212	23.070	EPSD	COSMIC	19.022	Down-regulation
AGC_Akt_AKT2_ST	Q7Z6J0	SH3RF1	P31751	AKT2	S735	R730Q	730	Missense	distal	-5	no	27.962	23.629	EPSD	COSMIC	19.022	Down-regulation
AGC_Akt_AKT2_ST	Q7Z6J0	SH3RF1	P31751	AKT2	S735	S735F	735	Missense	central	0	yes	27.962	0.000	EPSD	COSMIC	19.022	Loss
AGC_Akt_AKT2_ST	Q7Z6J0	SH3RF1	P31751	AKT2	T782	T782M	782	Missense	central	0	yes	19.462	0.000	EPSD	COSMIC	19.022	Loss
AGC_Akt_AKT2_ST	Q7Z6J0	SH3RF1	P31751	AKT2	S800	P807L	807	Missense	distal	7	no	29.656	29.351	EPSD	COSMIC	19.022	Down-regulation
AGC_Akt_AKT2_ST	Q7Z6J0	SH3RF1	P31751	AKT2	S817	S818F	818	Missense	proximal	1	no	17.583	19.173	EPSD	COSMIC	19.022	Gain
AGC_Akt_AKT2_ST	Q15118	PDK1	P31751	AKT2	T346	R348H	348	Missense	proximal	2	no	28.433	29.163	PhosphoSitePlus	COSMIC;GDSC	19.022	Up-regulation
AGC_Akt_AKT2_ST	Q15118	PDK1	P31751	AKT2	T346	R343C	343	Missense	distal	-3	no	28.433	-5.576	PhosphoSitePlus	COSMIC	19.022	Loss
AGC_Akt_AKT2_ST	Q15118	PDK1	P31751	AKT2	T346	R348C	348	Missense	proximal	2	no	28.433	29.931	PhosphoSitePlus	COSMIC	19.022	Up-regulation
AGC_Akt_AKT2_ST	Q15118	PDK1	P31751	AKT2	S347	R348C	348	Missense	proximal	1	no	17.334	19.483	EPSD	COSMIC	19.022	Gain
AGC_Akt_AKT2_ST	Q15118	PDK1	P31751	AKT2	S393	L392V	392	Missense	proximal	-1	no	21.110	22.031	EPSD	COSMIC	19.022	Up-regulation
AGC_Akt_AKT2_ST	P30405	PPIF	P31751	AKT2	S40	L47I	47	Missense	distal	7	no	20.686	20.907	EPSD	COSMIC;CCLE	19.022	Up-regulation
AGC_Akt_AKT2_ST	P04406	GAPDH	P31751	AKT2	S25	T19S	19	Missense	distal	-6	no	20.612	20.547	EPSD	COSMIC	19.022	Down-regulation
AGC_Akt_AKT2_ST	P04406	GAPDH	P31751	AKT2	S83	I76M	76	Missense	distal	-7	no	25.675	25.411	EPSD	COSMIC	19.022	Down-regulation
AGC_Akt_AKT2_ST	P04406	GAPDH	P31751	AKT2	S83	R80P	80	Missense	distal	-3	no	25.675	19.397	EPSD	COSMIC	19.022	Down-regulation
AGC_Akt_AKT2_ST	P04406	GAPDH	P31751	AKT2	T211	S210F	210	Missense	proximal	-1	no	19.326	18.296	EPSD	COSMIC	19.022	Loss
AGC_Akt_AKT2_ST	P04406	GAPDH	P31751	AKT2	T211	P208T	208	Missense	distal	-3	no	19.326	12.995	EPSD	COSMIC	19.022	Loss
AGC_Akt_AKT2_ST	P04406	GAPDH	P31751	AKT2	T237	N239K	239	Missense	proximal	2	no	29.610	28.568	PhosphoSitePlus	COSMIC	19.022	Down-regulation
AGC_Akt_AKT2_ST	P04406	GAPDH	P31751	AKT2	T237	D244N	244	Missense	distal	7	no	29.610	29.468	PhosphoSitePlus	COSMIC	19.022	Down-regulation
CMGC_DYRK_HIPK_HIPK3_ST	Q9UER7	DAXX	Q9H422	HIPK3	S33	A31V	31	Missense	proximal	-2	no	4.350	4.403	EPSD	COSMIC	1.096	Up-regulation
CMGC_DYRK_HIPK_HIPK3_ST	Q9UER7	DAXX	Q9H422	HIPK3	S178	R185C	185	Missense	distal	7	no	4.314	4.182	EPSD	COSMIC	1.096	Down-regulation
CMGC_DYRK_HIPK_HIPK3_ST	Q9UER7	DAXX	Q9H422	HIPK3	S178	Q177E	177	Missense	proximal	-1	no	4.314	4.303	EPSD	COSMIC	1.096	Down-regulation
CMGC_DYRK_HIPK_HIPK3_ST	Q9UER7	DAXX	Q9H422	HIPK3	S184	R185C	185	Missense	proximal	1	no	1.097	1.293	EPSD	COSMIC	1.096	Up-regulation
CMGC_DYRK_HIPK_HIPK3_ST	Q9UER7	DAXX	Q9H422	HIPK3	S184	Q177E	177	Missense	distal	-7	no	1.097	0.455	EPSD	COSMIC	1.096	Loss
CMGC_DYRK_HIPK_HIPK3_ST	Q9UER7	DAXX	Q9H422	HIPK3	S213	S220P	220	Missense	distal	7	no	0.946	1.234	EPSD	COSMIC	1.096	Gain
CMGC_DYRK_HIPK_HIPK3_ST	Q9UER7	DAXX	Q9H422	HIPK3	S403	E410K	410	Missense	distal	7	no	1.099	1.283	EPSD	COSMIC	1.096	Up-regulation
CMGC_DYRK_HIPK_HIPK3_ST	Q9UER7	DAXX	Q9H422	HIPK3	S403	S403F	403	Missense	central	0	yes	1.099	0.000	EPSD	COSMIC	1.096	Loss
CMGC_DYRK_HIPK_HIPK3_ST	Q9UER7	DAXX	Q9H422	HIPK3	S403	A396S	396	Missense	distal	-7	no	1.099	1.562	EPSD	COSMIC	1.096	Up-regulation
CMGC_DYRK_HIPK_HIPK3_ST	Q9UER7	DAXX	Q9H422	HIPK3	S403	S405C	405	Missense	proximal	2	no	1.099	1.104	EPSD	COSMIC	1.096	Up-regulation
CMGC_DYRK_HIPK_HIPK3_ST	Q9UER7	DAXX	Q9H422	HIPK3	S403	R397Q	397	Missense	distal	-6	no	1.099	1.097	EPSD	COSMIC	1.096	Down-regulation
CMGC_DYRK_HIPK_HIPK3_ST	Q9UER7	DAXX	Q9H422	HIPK3	T408	A411G	411	Missense	distal	3	no	4.038	4.002	EPSD	COSMIC	1.096	Down-regulation
CMGC_DYRK_HIPK_HIPK3_ST	Q9UER7	DAXX	Q9H422	HIPK3	T408	E410K	410	Missense	proximal	2	no	4.038	4.042	EPSD	COSMIC	1.096	Up-regulation
CMGC_DYRK_HIPK_HIPK3_ST	Q9UER7	DAXX	Q9H422	HIPK3	T408	A411S	411	Missense	distal	3	no	4.038	4.041	EPSD	COSMIC	1.096	Up-regulation
CMGC_DYRK_HIPK_HIPK3_ST	Q9UER7	DAXX	Q9H422	HIPK3	T408	S403F	403	Missense	distal	-5	no	4.038	3.997	EPSD	COSMIC	1.096	Down-regulation
CMGC_DYRK_HIPK_HIPK3_ST	Q9UER7	DAXX	Q9H422	HIPK3	T408	S405C	405	Missense	distal	-3	no	4.038	4.121	EPSD	COSMIC	1.096	Up-regulation
CMGC_DYRK_HIPK_HIPK3_ST	Q9UER7	DAXX	Q9H422	HIPK3	S495	P496T	496	Missense	proximal	1	no	4.280	0.198	EPSD	COSMIC	1.096	Loss
CMGC_DYRK_HIPK_HIPK3_ST	Q9UER7	DAXX	Q9H422	HIPK3	S495	S498P	498	Missense	distal	3	no	4.280	4.239	EPSD	COSMIC	1.096	Down-regulation
CMGC_DYRK_HIPK_HIPK3_ST	Q9UER7	DAXX	Q9H422	HIPK3	S495	D491N	491	Missense	distal	-4	no	4.280	4.286	EPSD	COSMIC	1.096	Up-regulation
CMGC_DYRK_HIPK_HIPK3_ST	Q9UER7	DAXX	Q9H422	HIPK3	S495	P496L	496	Missense	proximal	1	no	4.280	-0.141	EPSD	COSMIC	1.096	Loss
CMGC_DYRK_HIPK_HIPK3_ST	Q9UER7	DAXX	Q9H422	HIPK3	S561	E560Q	560	Missense	proximal	-1	no	4.001	4.011	EPSD	COSMIC	1.096	Up-regulation
CMGC_DYRK_HIPK_HIPK3_ST	Q9UER7	DAXX	Q9H422	HIPK3	S561	E568Q	568	Missense	distal	7	no	4.001	3.978	EPSD	COSMIC	1.096	Down-regulation
CMGC_DYRK_HIPK_HIPK3_ST	Q9UER7	DAXX	Q9H422	HIPK3	S561	F567S	567	Missense	distal	6	no	4.001	3.941	EPSD	COSMIC	1.096	Down-regulation
CMGC_DYRK_HIPK_HIPK3_ST	Q9UER7	DAXX	Q9H422	HIPK3	S561	E559K	559	Missense	proximal	-2	no	4.001	3.916	EPSD	COSMIC	1.096	Down-regulation
CMGC_DYRK_HIPK_HIPK3_ST	Q9UER7	DAXX	Q9H422	HIPK3	T578	S581F	581	Missense	distal	3	no	3.923	3.863	EPSD	COSMIC	1.096	Down-regulation
CMGC_DYRK_HIPK_HIPK3_ST	Q9UER7	DAXX	Q9H422	HIPK3	T578	D577Y	577	Missense	proximal	-1	no	3.923	3.920	EPSD	COSMIC;GDSC;CCLE	1.096	Down-regulation
CMGC_DYRK_HIPK_HIPK3_ST	Q9UER7	DAXX	Q9H422	HIPK3	T578	T584M	584	Missense	distal	6	no	3.923	3.927	EPSD	COSMIC	1.096	Up-regulation
CMGC_DYRK_HIPK_HIPK3_ST	Q9UER7	DAXX	Q9H422	HIPK3	T578	S581C	581	Missense	distal	3	no	3.923	3.809	EPSD	COSMIC	1.096	Down-regulation
CMGC_DYRK_HIPK_HIPK3_ST	Q9UER7	DAXX	Q9H422	HIPK3	T599	S593C	593	Missense	distal	-6	no	1.492	1.477	EPSD	COSMIC	1.096	Down-regulation
CMGC_DYRK_HIPK_HIPK3_ST	Q9UER7	DAXX	Q9H422	HIPK3	T599	G604A	604	Missense	distal	5	no	1.492	1.496	EPSD	COSMIC	1.096	Up-regulation
CMGC_DYRK_HIPK_HIPK3_ST	Q9UER7	DAXX	Q9H422	HIPK3	T599	P596L	596	Missense	distal	-3	no	1.492	1.440	EPSD	COSMIC	1.096	Down-regulation
CMGC_DYRK_HIPK_HIPK3_ST	Q9UER7	DAXX	Q9H422	HIPK3	T599	G606V	606	Missense	distal	7	no	1.492	1.409	EPSD	COSMIC	1.096	Down-regulation
CMGC_DYRK_HIPK_HIPK3_ST	Q9UER7	DAXX	Q9H422	HIPK3	S618	H620Q	620	Missense	proximal	2	no	3.837	3.842	EPSD	COSMIC	1.096	Up-regulation
CMGC_DYRK_HIPK_HIPK3_ST	Q9UER7	DAXX	Q9H422	HIPK3	S618	P619S	619	Missense	proximal	1	no	3.837	-0.796	EPSD	COSMIC	1.096	Loss
CMGC_DYRK_HIPK_HIPK3_ST	Q9UER7	DAXX	Q9H422	HIPK3	S618	W622C	622	Missense	distal	4	no	3.837	3.818	EPSD	COSMIC	1.096	Down-regulation
CMGC_DYRK_HIPK_HIPK3_ST	Q9UER7	DAXX	Q9H422	HIPK3	S618	S612F	612	Missense	distal	-6	no	3.837	3.808	EPSD	COSMIC	1.096	Down-regulation
CMGC_DYRK_HIPK_HIPK3_ST	Q9UER7	DAXX	Q9H422	HIPK3	S668	S675F	675	Missense	distal	7	no	4.666	4.830	PhosphoSitePlus	COSMIC	1.096	Up-regulation
CMGC_DYRK_HIPK_HIPK3_ST	Q9UER7	DAXX	Q9H422	HIPK3	S668	C664R	664	Missense	distal	-4	no	4.666	4.657	PhosphoSitePlus	COSMIC	1.096	Down-regulation
CMGC_DYRK_HIPK_HIPK3_ST	Q9UER7	DAXX	Q9H422	HIPK3	S668	S668C	668	Missense	central	0	yes	4.666	0.000	PhosphoSitePlus	COSMIC	1.096	Loss
CMGC_DYRK_HIPK_HIPK3_ST	Q9UER7	DAXX	Q9H422	HIPK3	S668	S668N	668	Missense	central	0	yes	4.666	0.000	PhosphoSitePlus	COSMIC	1.096	Loss
CMGC_DYRK_HIPK_HIPK3_ST	Q9UER7	DAXX	Q9H422	HIPK3	S668	T665I	665	Missense	distal	-3	no	4.666	4.657	PhosphoSitePlus	COSMIC	1.096	Down-regulation
CMGC_DYRK_HIPK_HIPK3_ST	Q9UER7	DAXX	Q9H422	HIPK3	S671	S675F	675	Missense	distal	4	no	3.219	3.218	EPSD	COSMIC	1.096	Down-regulation
CMGC_DYRK_HIPK_HIPK3_ST	Q9UER7	DAXX	Q9H422	HIPK3	S671	A677V	677	Missense	distal	6	no	3.219	3.257	EPSD	COSMIC	1.096	Up-regulation
CMGC_DYRK_HIPK_HIPK3_ST	Q9UER7	DAXX	Q9H422	HIPK3	S671	C664R	664	Missense	distal	-7	no	3.219	3.163	EPSD	COSMIC	1.096	Down-regulation
CMGC_DYRK_HIPK_HIPK3_ST	Q9UER7	DAXX	Q9H422	HIPK3	S671	S668C	668	Missense	distal	-3	no	3.219	3.301	EPSD	COSMIC	1.096	Up-regulation
CMGC_DYRK_HIPK_HIPK3_ST	Q9UER7	DAXX	Q9H422	HIPK3	S671	S668N	668	Missense	distal	-3	no	3.219	3.302	EPSD	COSMIC	1.096	Up-regulation
CMGC_DYRK_HIPK_HIPK3_ST	Q9UER7	DAXX	Q9H422	HIPK3	S671	T665I	665	Missense	distal	-6	no	3.219	3.233	EPSD	COSMIC	1.096	Up-regulation
CMGC_DYRK_HIPK_HIPK3_ST	Q9UER7	DAXX	Q9H422	HIPK3	S688	S688C	688	Missense	central	0	yes	4.728	0.000	EPSD	COSMIC	1.096	Loss
CMGC_DYRK_HIPK_HIPK3_ST	Q9UER7	DAXX	Q9H422	HIPK3	S688	S682F	682	Missense	distal	-6	no	4.728	4.698	EPSD	COSMIC	1.096	Down-regulation
CMGC_DYRK_HIPK_HIPK3_ST	Q9UER7	DAXX	Q9H422	HIPK3	S702	C699Y	699	Missense	distal	-3	no	4.960	4.927	EPSD	COSMIC	1.096	Down-regulation
CMGC_DYRK_HIPK_HIPK3_ST	Q9UER7	DAXX	Q9H422	HIPK3	S702	L698F	698	Missense	distal	-4	no	4.960	4.980	EPSD	COSMIC	1.096	Up-regulation
CMGC_DYRK_HIPK_HIPK3_ST	Q9UER7	DAXX	Q9H422	HIPK3	S702	R705W	705	Missense	distal	3	no	4.960	4.995	EPSD	COSMIC;GDSC;CCLE	1.096	Up-regulation
CMGC_DYRK_HIPK_HIPK3_ST	Q9UER7	DAXX	Q9H422	HIPK3	S702	R705L	705	Missense	distal	3	no	4.960	4.936	EPSD	COSMIC	1.096	Down-regulation
CMGC_DYRK_HIPK_HIPK3_ST	Q9UER7	DAXX	Q9H422	HIPK3	S702	P703S	703	Missense	proximal	1	no	4.960	0.327	EPSD	COSMIC	1.096	Loss
CMGC_DYRK_HIPK_HIPK3_ST	Q9UER7	DAXX	Q9H422	HIPK3	T709	R705W	705	Missense	distal	-4	no	4.852	4.859	EPSD	COSMIC;GDSC;CCLE	1.096	Up-regulation
CMGC_DYRK_HIPK_HIPK3_ST	Q9UER7	DAXX	Q9H422	HIPK3	T709	H711Y	711	Missense	proximal	2	no	4.852	4.851	EPSD	COSMIC	1.096	Down-regulation
CMGC_DYRK_HIPK_HIPK3_ST	Q9UER7	DAXX	Q9H422	HIPK3	T709	R705L	705	Missense	distal	-4	no	4.852	4.853	EPSD	COSMIC	1.096	Up-regulation
CMGC_DYRK_HIPK_HIPK3_ST	Q9UER7	DAXX	Q9H422	HIPK3	T709	P703S	703	Missense	distal	-6	no	4.852	4.781	EPSD	COSMIC	1.096	Down-regulation
AGC_PKC_PKCa_PRKCB_ST	Q96PH1	NOX5	P05771	PRKCB	S521	F522L	522	Missense	proximal	1	no	2.239	1.739	EPSD	COSMIC	0.942	Down-regulation
AGC_PKC_PKCa_PRKCB_ST	Q96PH1	NOX5	P05771	PRKCB	S536	G529S	529	Missense	distal	-7	no	4.376	4.295	EPSD	COSMIC	0.942	Down-regulation
AGC_PKC_PKCa_PRKCB_ST	Q96PH1	NOX5	P05771	PRKCB	S536	R537S	537	Missense	proximal	1	no	4.376	2.352	EPSD	COSMIC	0.942	Down-regulation
AGC_PKC_PKCa_PRKCB_ST	Q96PH1	NOX5	P05771	PRKCB	S536	M541I	541	Missense	distal	5	no	4.376	4.495	EPSD	COSMIC	0.942	Up-regulation
AGC_PKC_PKCa_PRKCB_ST	Q96PH1	NOX5	P05771	PRKCB	S536	R530S	530	Missense	distal	-6	no	4.376	4.163	EPSD	COSMIC	0.942	Down-regulation
AGC_PKC_PKCa_PRKCB_ST	Q96PH1	NOX5	P05771	PRKCB	S536	V539L	539	Missense	distal	3	no	4.376	4.425	EPSD	COSMIC	0.942	Up-regulation
AGC_PKC_PKCa_PRKCB_ST	Q96PH1	NOX5	P05771	PRKCB	S536	T540I	540	Missense	distal	4	no	4.376	4.546	EPSD	COSMIC	0.942	Up-regulation
AGC_PKC_PKCa_PRKCB_ST	Q96PH1	NOX5	P05771	PRKCB	T540	S547L	547	Missense	distal	7	no	5.403	5.463	EPSD	COSMIC	0.942	Up-regulation
AGC_PKC_PKCa_PRKCB_ST	Q96PH1	NOX5	P05771	PRKCB	T540	R537S	537	Missense	distal	-3	no	5.403	2.007	EPSD	COSMIC	0.942	Down-regulation
AGC_PKC_PKCa_PRKCB_ST	Q96PH1	NOX5	P05771	PRKCB	T540	M541I	541	Missense	proximal	1	no	5.403	6.413	EPSD	COSMIC	0.942	Up-regulation
AGC_PKC_PKCa_PRKCB_ST	Q96PH1	NOX5	P05771	PRKCB	T540	V539L	539	Missense	proximal	-1	no	5.403	5.262	EPSD	COSMIC	0.942	Down-regulation
AGC_PKC_PKCa_PRKCB_ST	Q96PH1	NOX5	P05771	PRKCB	T540	T540I	540	Missense	central	0	yes	5.403	0.000	EPSD	COSMIC	0.942	Loss
AGC_PKC_PKCa_PRKCB_ST	Q96PH1	NOX5	P05771	PRKCB	S544	S547L	547	Missense	distal	3	no	7.783	7.462	EPSD	COSMIC	0.942	Down-regulation
AGC_PKC_PKCa_PRKCB_ST	Q96PH1	NOX5	P05771	PRKCB	S544	R537S	537	Missense	distal	-7	no	7.783	8.053	EPSD	COSMIC	0.942	Up-regulation
AGC_PKC_PKCa_PRKCB_ST	Q96PH1	NOX5	P05771	PRKCB	S544	M541I	541	Missense	distal	-3	no	7.783	7.590	EPSD	COSMIC	0.942	Down-regulation
AGC_PKC_PKCa_PRKCB_ST	Q96PH1	NOX5	P05771	PRKCB	S544	K549R	549	Missense	distal	5	no	7.783	7.721	EPSD	COSMIC	0.942	Down-regulation
AGC_PKC_PKCa_PRKCB_ST	Q96PH1	NOX5	P05771	PRKCB	S544	V539L	539	Missense	distal	-5	no	7.783	7.763	EPSD	COSMIC	0.942	Down-regulation
AGC_PKC_PKCa_PRKCB_ST	Q96PH1	NOX5	P05771	PRKCB	S544	T540I	540	Missense	distal	-4	no	7.783	7.804	EPSD	COSMIC	0.942	Up-regulation
AGC_PKC_PKCa_PRKCB_ST	Q96PH1	NOX5	P05771	PRKCB	S705	I706T	706	Missense	proximal	1	no	4.320	3.211	EPSD	COSMIC	0.942	Down-regulation
AGC_PKC_PKCa_PRKCB_ST	Q96PH1	NOX5	P05771	PRKCB	S705	T711M	711	Missense	distal	6	no	4.320	4.155	EPSD	COSMIC	0.942	Down-regulation
AGC_PKC_PKCa_PRKCB_ST	Q96PH1	NOX5	P05771	PRKCB	S705	G708R	708	Missense	distal	3	no	4.320	5.348	EPSD	COSMIC	0.942	Up-regulation
AGC_PKC_PKCa_PRKCB_ST	P04083	ANXA1	P05771	PRKCB	S27	G33R	33	Missense	distal	6	no	3.204	4.630	EPSD	COSMIC	0.942	Up-regulation
AGC_PKC_PKCa_PRKCB_ST	P04083	ANXA1	P05771	PRKCB	S28	G33R	33	Missense	distal	5	no	1.132	1.562	PhosphoSitePlus	COSMIC	0.942	Up-regulation
AGC_PKC_PKCa_PRKCB_ST	P04083	ANXA1	P05771	PRKCB	S244	D247Y	247	Missense	distal	3	no	1.681	1.560	EPSD	COSMIC	0.942	Down-regulation
AGC_PKC_PKCa_PRKCB_ST	P04083	ANXA1	P05771	PRKCB	S244	T241A	241	Missense	distal	-3	no	1.681	0.235	EPSD	COSMIC	0.942	Loss
AGC_PKC_PKCa_PRKCB_ST	P10636	MAPT	P05771	PRKCB	T167	E165K	165	Missense	proximal	-2	no	0.079	1.523	EPSD	COSMIC	0.942	Gain
AGC_PKC_PKCa_PRKCB_ST	P10636	MAPT	P05771	PRKCB	S171	P175S	175	Missense	distal	4	no	2.924	2.789	EPSD	COSMIC	0.942	Down-regulation
AGC_PKC_PKCa_PRKCB_ST	P10636	MAPT	P05771	PRKCB	S171	A166V	166	Missense	distal	-5	no	2.924	2.895	EPSD	COSMIC;CCLE	0.942	Down-regulation
AGC_PKC_PKCa_PRKCB_ST	P10636	MAPT	P05771	PRKCB	S171	E176G	176	Missense	distal	5	no	2.924	2.603	EPSD	COSMIC	0.942	Down-regulation
AGC_PKC_PKCa_PRKCB_ST	P10636	MAPT	P05771	PRKCB	S171	D177G	177	Missense	distal	6	no	2.924	2.243	EPSD	COSMIC	0.942	Down-regulation
AGC_PKC_PKCa_PRKCB_ST	P10636	MAPT	P05771	PRKCB	S171	E165K	165	Missense	distal	-6	no	2.924	3.069	EPSD	COSMIC	0.942	Up-regulation
AGC_PKC_PKCa_PRKCB_ST	P10636	MAPT	P05771	PRKCB	S171	G172V	172	Missense	proximal	1	no	2.924	3.996	EPSD	COSMIC	0.942	Up-regulation
AGC_PKC_PKCa_PRKCB_ST	P10636	MAPT	P05771	PRKCB	S214	E210Q	210	Missense	distal	-4	no	1.656	1.568	EPSD	COSMIC	0.942	Down-regulation
AGC_PKC_PKCa_PRKCB_ST	P10636	MAPT	P05771	PRKCB	S214	G207E	207	Missense	distal	-7	no	1.656	1.463	EPSD	COSMIC	0.942	Down-regulation
AGC_PKC_PKCa_PRKCB_ST	P10636	MAPT	P05771	PRKCB	S228	Q230R	230	Missense	proximal	2	no	-4.307	2.242	EPSD	COSMIC	0.942	Gain
AGC_PKC_PKCa_PRKCB_ST	P10636	MAPT	P05771	PRKCB	S235	A237T	237	Missense	proximal	2	no	-1.607	1.750	EPSD	COSMIC	0.942	Gain
AGC_PKC_PKCa_PRKCB_ST	P10636	MAPT	P05771	PRKCB	S341	G343R	343	Missense	proximal	2	no	-2.002	6.732	EPSD	COSMIC	0.942	Gain
AGC_PKC_PKCa_PRKCB_ST	P10636	MAPT	P05771	PRKCB	S355	A361S	361	Missense	distal	6	no	3.476	3.834	EPSD	COSMIC;GDSC;CCLE	0.942	Up-regulation
AGC_PKC_PKCa_PRKCB_ST	P10636	MAPT	P05771	PRKCB	S355	P354L	354	Missense	proximal	-1	no	3.476	3.527	EPSD	COSMIC	0.942	Up-regulation
AGC_PKC_PKCa_PRKCB_ST	P10636	MAPT	P05771	PRKCB	S369	V368I	368	Missense	proximal	-1	no	3.530	3.422	EPSD	COSMIC	0.942	Down-regulation
AGC_PKC_PKCa_PRKCB_ST	P10636	MAPT	P05771	PRKCB	S369	R370W	370	Missense	proximal	1	no	3.530	0.857	EPSD	COSMIC	0.942	Loss
AGC_PKC_PKCa_PRKCB_ST	P10636	MAPT	P05771	PRKCB	S396	R398C	398	Missense	proximal	2	no	3.192	-1.301	EPSD	COSMIC	0.942	Loss
AGC_PKC_PKCa_PRKCB_ST	P10636	MAPT	P05771	PRKCB	S396	S396F	396	Missense	central	0	yes	3.192	0.000	EPSD	COSMIC	0.942	Loss
AGC_PKC_PKCa_PRKCB_ST	P10636	MAPT	P05771	PRKCB	S396	D389N	389	Missense	distal	-7	no	3.192	3.368	EPSD	COSMIC;GDSC;CCLE	0.942	Up-regulation
AGC_PKC_PKCa_PRKCB_ST	P10636	MAPT	P05771	PRKCB	S400	R398C	398	Missense	proximal	-2	no	5.186	3.720	EPSD	COSMIC	0.942	Down-regulation
AGC_PKC_PKCa_PRKCB_ST	P10636	MAPT	P05771	PRKCB	S400	S396F	396	Missense	distal	-4	no	5.186	5.164	EPSD	COSMIC	0.942	Down-regulation
AGC_PKC_PKCa_PRKCB_ST	P10636	MAPT	P05771	PRKCB	T403	L410F	410	Missense	distal	7	no	1.137	1.134	EPSD	COSMIC	0.942	Down-regulation
AGC_PKC_PKCa_PRKCB_ST	P10636	MAPT	P05771	PRKCB	T403	R398C	398	Missense	distal	-5	no	1.137	0.903	EPSD	COSMIC	0.942	Loss
AGC_PKC_PKCa_PRKCB_ST	P10636	MAPT	P05771	PRKCB	T403	S396F	396	Missense	distal	-7	no	1.137	1.209	EPSD	COSMIC	0.942	Up-regulation
AGC_PKC_PKCa_PRKCB_ST	P10636	MAPT	P05771	PRKCB	S438	S443Y	443	Missense	distal	5	no	1.209	1.302	EPSD	COSMIC	0.942	Up-regulation
AGC_PKC_PKCa_PRKCB_ST	P10636	MAPT	P05771	PRKCB	T470	T466M	466	Missense	distal	-4	no	3.997	4.034	EPSD	COSMIC;GDSC;CCLE	0.942	Up-regulation
AGC_PKC_PKCa_PRKCB_ST	P10636	MAPT	P05771	PRKCB	T470	K467T	467	Missense	distal	-3	no	3.997	1.284	EPSD	COSMIC	0.942	Down-regulation
AGC_PKC_PKCa_PRKCB_ST	P10636	MAPT	P05771	PRKCB	T470	P477L	477	Missense	distal	7	no	3.997	3.964	EPSD	COSMIC	0.942	Down-regulation
AGC_PKC_PKCa_PRKCB_ST	P10636	MAPT	P05771	PRKCB	T470	P477S	477	Missense	distal	7	no	3.997	3.904	EPSD	COSMIC	0.942	Down-regulation
AGC_PKC_PKCa_PRKCB_ST	P10636	MAPT	P05771	PRKCB	S525	G521V	521	Missense	distal	-4	no	1.150	0.969	EPSD	COSMIC	0.942	Down-regulation
AGC_PKC_PKCa_PRKCB_ST	P10636	MAPT	P05771	PRKCB	S525	R526H	526	Missense	proximal	1	no	1.150	-0.557	EPSD	COSMIC	0.942	Loss
AGC_PKC_PKCa_PRKCB_ST	P10636	MAPT	P05771	PRKCB	S525	G518V	518	Missense	distal	-7	no	1.150	1.075	EPSD	COSMIC	0.942	Down-regulation
AGC_PKC_PKCa_PRKCB_ST	P10636	MAPT	P05771	PRKCB	S525	R528S	528	Missense	distal	3	no	1.150	0.384	EPSD	COSMIC	0.942	Loss
AGC_PKC_PKCa_PRKCB_ST	P10636	MAPT	P05771	PRKCB	S525	P530S	530	Missense	distal	5	no	1.150	1.207	EPSD	COSMIC	0.942	Up-regulation
AGC_PKC_PKCa_PRKCB_ST	P10636	MAPT	P05771	PRKCB	S531	R526H	526	Missense	distal	-5	no	1.751	1.503	EPSD	COSMIC	0.942	Down-regulation
AGC_PKC_PKCa_PRKCB_ST	P10636	MAPT	P05771	PRKCB	S531	R528S	528	Missense	distal	-3	no	1.751	-1.646	EPSD	COSMIC	0.942	Loss
AGC_PKC_PKCa_PRKCB_ST	P10636	MAPT	P05771	PRKCB	S531	P530S	530	Missense	proximal	-1	no	1.751	1.810	EPSD	COSMIC	0.942	Up-regulation
AGC_PKC_PKCa_PRKCB_ST	P10636	MAPT	P05771	PRKCB	S531	P536H	536	Missense	distal	5	no	1.751	1.837	EPSD	COSMIC	0.942	Up-regulation
AGC_PKC_PKCa_PRKCB_ST	P10636	MAPT	P05771	PRKCB	S531	P535Q	535	Missense	distal	4	no	1.751	2.014	EPSD	COSMIC	0.942	Up-regulation
AGC_PKC_PKCa_PRKCB_ST	P10636	MAPT	P05771	PRKCB	S555	P550S	550	Missense	distal	-5	no	2.171	2.197	EPSD	COSMIC	0.942	Up-regulation
AGC_PKC_PKCa_PRKCB_ST	P10636	MAPT	P05771	PRKCB	S555	R559C	559	Missense	distal	4	no	2.171	1.032	EPSD	COSMIC	0.942	Down-regulation
AGC_PKC_PKCa_PRKCB_ST	P10636	MAPT	P05771	PRKCB	S555	P553R	553	Missense	proximal	-2	no	2.171	4.003	EPSD	COSMIC	0.942	Up-regulation
AGC_PKC_PKCa_PRKCB_ST	P10636	MAPT	P05771	PRKCB	S555	P553L	553	Missense	proximal	-2	no	2.171	1.483	EPSD	COSMIC	0.942	Down-regulation
AGC_PKC_PKCa_PRKCB_ST	P10636	MAPT	P05771	PRKCB	S555	P549L	549	Missense	distal	-6	no	2.171	2.186	EPSD	COSMIC	0.942	Up-regulation
AGC_PKC_PKCa_PRKCB_ST	P10636	MAPT	P05771	PRKCB	S555	S555F	555	Missense	central	0	yes	2.171	0.000	EPSD	COSMIC	0.942	Loss
AGC_PKC_PKCa_PRKCB_ST	P10636	MAPT	P05771	PRKCB	S555	P553Q	553	Missense	proximal	-2	no	2.171	3.031	EPSD	COSMIC	0.942	Up-regulation
AGC_PKC_PKCa_PRKCB_ST	P10636	MAPT	P05771	PRKCB	S606	N613D	613	Missense	distal	7	no	1.921	1.841	EPSD	COSMIC	0.942	Down-regulation
AGC_PKC_PKCa_PRKCB_ST	P10636	MAPT	P05771	PRKCB	S606	S602G	602	Missense	distal	-4	no	1.921	2.014	EPSD	COSMIC	0.942	Up-regulation
AGC_PKC_PKCa_PRKCB_ST	P10636	MAPT	P05771	PRKCB	S606	C608W	608	Missense	proximal	2	no	1.921	-3.099	EPSD	COSMIC	0.942	Loss
AGC_PKC_PKCa_PRKCB_ST	P10636	MAPT	P05771	PRKCB	S606	S610L	610	Missense	distal	4	no	1.921	1.633	EPSD	COSMIC	0.942	Down-regulation
AGC_PKC_PKCa_PRKCB_ST	P10636	MAPT	P05771	PRKCB	S606	D600E	600	Missense	distal	-6	no	1.921	2.018	EPSD	COSMIC	0.942	Up-regulation
AGC_PKC_PKCa_PRKCB_ST	P10636	MAPT	P05771	PRKCB	S610	N613D	613	Missense	distal	3	no	2.799	2.743	EPSD	COSMIC	0.942	Down-regulation
AGC_PKC_PKCa_PRKCB_ST	P10636	MAPT	P05771	PRKCB	S610	C608W	608	Missense	proximal	-2	no	2.799	0.988	EPSD	COSMIC	0.942	Down-regulation
AGC_PKC_PKCa_PRKCB_ST	P10636	MAPT	P05771	PRKCB	S610	S610L	610	Missense	central	0	yes	2.799	0.000	EPSD	COSMIC	0.942	Loss
AGC_PKC_PKCa_PRKCB_ST	P10636	MAPT	P05771	PRKCB	S633	S633N	633	Missense	central	0	yes	1.139	0.000	EPSD	COSMIC	0.942	Loss
AGC_PKC_PKCa_PRKCB_ST	P10636	MAPT	P05771	PRKCB	S633	S633I	633	Missense	central	0	yes	1.139	0.000	EPSD	COSMIC	0.942	Loss
AGC_PKC_PKCa_PRKCB_ST	P10636	MAPT	P05771	PRKCB	S637	S633N	633	Missense	distal	-4	no	4.072	4.054	EPSD	COSMIC	0.942	Down-regulation
AGC_PKC_PKCa_PRKCB_ST	P10636	MAPT	P05771	PRKCB	S637	S633I	633	Missense	distal	-4	no	4.072	4.043	EPSD	COSMIC	0.942	Down-regulation
AGC_PKC_PKCa_PRKCB_ST	P10636	MAPT	P05771	PRKCB	S658	D662G	662	Missense	distal	4	no	3.767	3.353	EPSD	COSMIC	0.942	Down-regulation
AGC_PKC_PKCa_PRKCB_ST	P10636	MAPT	P05771	PRKCB	S658	K664N	664	Missense	distal	6	no	3.767	3.138	EPSD	COSMIC	0.942	Down-regulation
AGC_PKC_PKCa_PRKCB_ST	P10636	MAPT	P05771	PRKCB	S669	S669L	669	Missense	central	0	yes	3.675	0.000	EPSD	COSMIC	0.942	Loss
AGC_PKC_PKCa_PRKCB_ST	P10636	MAPT	P05771	PRKCB	S669	R666K	666	Missense	distal	-3	no	3.675	3.906	EPSD	COSMIC	0.942	Up-regulation
AGC_PKC_PKCa_PRKCB_ST	P10636	MAPT	P05771	PRKCB	S669	D662G	662	Missense	distal	-7	no	3.675	3.945	EPSD	COSMIC	0.942	Up-regulation
AGC_PKC_PKCa_PRKCB_ST	P10636	MAPT	P05771	PRKCB	S669	S673F	673	Missense	distal	4	no	3.675	3.525	EPSD	COSMIC	0.942	Down-regulation
AGC_PKC_PKCa_PRKCB_ST	P10636	MAPT	P05771	PRKCB	S669	K670N	670	Missense	proximal	1	no	3.675	0.855	EPSD	COSMIC	0.942	Loss
AGC_PKC_PKCa_PRKCB_ST	P10636	MAPT	P05771	PRKCB	S669	K664N	664	Missense	distal	-5	no	3.675	3.508	EPSD	COSMIC	0.942	Down-regulation
AGC_PKC_PKCa_PRKCB_ST	P10636	MAPT	P05771	PRKCB	S669	L674Q	674	Missense	distal	5	no	3.675	4.154	EPSD	COSMIC	0.942	Up-regulation
AGC_PKC_PKCa_PRKCB_ST	P10636	MAPT	P05771	PRKCB	T690	R696H	696	Missense	distal	6	no	3.504	2.744	EPSD	COSMIC	0.942	Down-regulation
AGC_PKC_PKCa_PRKCB_ST	P10636	MAPT	P05771	PRKCB	T690	G683R	683	Missense	distal	-7	no	3.504	3.152	EPSD	COSMIC;CCLE	0.942	Down-regulation
AGC_PKC_PKCa_PRKCB_ST	P10636	MAPT	P05771	PRKCB	T690	G683E	683	Missense	distal	-7	no	3.504	3.312	EPSD	COSMIC	0.942	Down-regulation
AGC_PKC_PKCa_PRKCB_ST	P10636	MAPT	P05771	PRKCB	T690	R696C	696	Missense	distal	6	no	3.504	2.309	EPSD	COSMIC	0.942	Down-regulation
AGC_PKC_PKCa_PRKCB_ST	P10636	MAPT	P05771	PRKCB	T690	G684E	684	Missense	distal	-6	no	3.504	3.771	EPSD	COSMIC	0.942	Up-regulation
AGC_PKC_PKCa_PRKCB_ST	P10636	MAPT	P05771	PRKCB	T694	R696H	696	Missense	proximal	2	no	2.834	-3.528	EPSD	COSMIC	0.942	Loss
AGC_PKC_PKCa_PRKCB_ST	P10636	MAPT	P05771	PRKCB	T694	R696C	696	Missense	proximal	2	no	2.834	-1.659	EPSD	COSMIC	0.942	Loss
AGC_PKC_PKCa_PRKCB_ST	P10636	MAPT	P05771	PRKCB	S721	R723W	723	Missense	proximal	2	no	2.050	-7.464	EPSD	COSMIC	0.942	Loss
AGC_PKC_PKCa_PRKCB_ST	P10636	MAPT	P05771	PRKCB	S721	V728M	728	Missense	distal	7	no	2.050	2.047	EPSD	COSMIC	0.942	Down-regulation
AGC_PKC_PKCa_PRKCB_ST	P10636	MAPT	P05771	PRKCB	S721	V728A	728	Missense	distal	7	no	2.050	2.105	EPSD	COSMIC	0.942	Up-regulation
AGC_PKC_PKCa_PRKCB_ST	P05107	ITGB2	P05771	PRKCB	T118	A112T	112	Missense	distal	-6	no	4.279	4.419	EPSD	COSMIC	0.942	Up-regulation
AGC_PKC_PKCa_PRKCB_ST	P05107	ITGB2	P05771	PRKCB	S496	S503F	503	Missense	distal	7	no	3.467	3.525	EPSD	COSMIC	0.942	Up-regulation
AGC_PKC_PKCa_PRKCB_ST	P05107	ITGB2	P05771	PRKCB	S591	R586W	586	Missense	distal	-5	no	5.199	4.821	EPSD	COSMIC	0.942	Down-regulation
AGC_PKC_PKCa_PRKCB_ST	P05107	ITGB2	P05771	PRKCB	S591	R595Q	595	Missense	distal	4	no	5.199	4.580	EPSD	COSMIC;GDSC	0.942	Down-regulation
AGC_PKC_PKCa_PRKCB_ST	P05107	ITGB2	P05771	PRKCB	S591	R593H	593	Missense	proximal	2	no	5.199	-1.162	EPSD	COSMIC	0.942	Loss
AGC_PKC_PKCa_PRKCB_ST	P28799	GRN	P05771	PRKCB	T18	R19Q	19	Missense	proximal	1	no	1.080	0.382	EPSD	COSMIC;GDSC;CCLE	0.942	Loss
AGC_PKC_PKCa_PRKCB_ST	P28799	GRN	P05771	PRKCB	T18	G23C	23	Missense	distal	5	no	1.080	1.067	EPSD	COSMIC	0.942	Down-regulation
AGC_PKC_PKCa_PRKCB_ST	P28799	GRN	P05771	PRKCB	T18	R19W	19	Missense	proximal	1	no	1.080	-1.593	EPSD	COSMIC	0.942	Loss
AGC_PKC_PKCa_PRKCB_ST	P28799	GRN	P05771	PRKCB	T196	A199T	199	Missense	distal	3	no	0.723	1.116	EPSD	COSMIC	0.942	Gain
AGC_PKC_PKCa_PRKCB_ST	P28799	GRN	P05771	PRKCB	T196	A193V	193	Missense	distal	-3	no	0.723	2.435	EPSD	COSMIC	0.942	Gain
AGC_PKC_PKCa_PRKCB_ST	P28799	GRN	P05771	PRKCB	S435	R433W	433	Missense	proximal	-2	no	4.263	0.987	EPSD	COSMIC	0.942	Down-regulation
AGC_PKC_PKCa_PRKCB_ST	P28799	GRN	P05771	PRKCB	S435	S435F	435	Missense	central	0	yes	4.263	0.000	EPSD	COSMIC	0.942	Loss
AGC_PKC_PKCa_PRKCB_ST	P28799	GRN	P05771	PRKCB	S435	P430T	430	Missense	distal	-5	no	4.263	4.339	EPSD	COSMIC	0.942	Up-regulation
AGC_PKC_PKCa_PRKCB_ST	P28799	GRN	P05771	PRKCB	S435	A431S	431	Missense	distal	-4	no	4.263	4.207	EPSD	COSMIC	0.942	Down-regulation
AGC_PKC_PKCa_PRKCB_ST	P05771	PRKCB	P05771	PRKCB	S16	R22G	22	Missense	distal	6	no	2.322	0.895	EPSD	COSMIC	0.942	Loss
AGC_PKC_PKCa_PRKCB_ST	P05771	PRKCB	P05771	PRKCB	T17	R22G	22	Missense	distal	5	no	3.564	3.134	EPSD	COSMIC	0.942	Down-regulation
AGC_PKC_PKCa_PRKCB_ST	P05771	PRKCB	P05771	PRKCB	T17	G24D	24	Missense	distal	7	no	3.564	3.337	EPSD	COSMIC	0.942	Down-regulation
AGC_PKC_PKCa_PRKCB_ST	P05771	PRKCB	P05771	PRKCB	T40	T40A	40	Missense	central	0	yes	3.397	0.000	EPSD	COSMIC	0.942	Loss
AGC_PKC_PKCa_PRKCB_ST	P05771	PRKCB	P05771	PRKCB	T40	N36T	36	Missense	distal	-4	no	3.397	3.365	EPSD	COSMIC	0.942	Down-regulation
AGC_PKC_PKCa_PRKCB_ST	P05771	PRKCB	P05771	PRKCB	T48	C50S	50	Missense	proximal	2	no	2.065	0.561	EPSD	COSMIC	0.942	Loss
AGC_PKC_PKCa_PRKCB_ST	P05771	PRKCB	P05771	PRKCB	T48	D55H	55	Missense	distal	7	no	2.065	2.217	EPSD	COSMIC	0.942	Up-regulation
AGC_PKC_PKCa_PRKCB_ST	P05771	PRKCB	P05771	PRKCB	T48	C53Y	53	Missense	distal	5	no	2.065	2.195	EPSD	COSMIC	0.942	Up-regulation
AGC_PKC_PKCa_PRKCB_ST	P05771	PRKCB	P05771	PRKCB	S111	T108M	108	Missense	distal	-3	no	2.681	2.160	EPSD	COSMIC	0.942	Down-regulation
AGC_PKC_PKCa_PRKCB_ST	P05771	PRKCB	P05771	PRKCB	S111	Y109H	109	Missense	proximal	-2	no	2.681	2.308	EPSD	COSMIC	0.942	Down-regulation
AGC_PKC_PKCa_PRKCB_ST	P05771	PRKCB	P05771	PRKCB	T314	K320R	320	Missense	distal	6	no	1.587	1.436	EPSD	COSMIC	0.942	Down-regulation
AGC_PKC_PKCa_PRKCB_ST	P05771	PRKCB	P05771	PRKCB	T314	K320N	320	Missense	distal	6	no	1.587	0.958	EPSD	COSMIC	0.942	Down-regulation
AGC_PKC_PKCa_PRKCB_ST	P05771	PRKCB	P05771	PRKCB	T314	I310T	310	Missense	distal	-4	no	1.587	1.566	EPSD	COSMIC	0.942	Down-regulation
AGC_PKC_PKCa_PRKCB_ST	P05771	PRKCB	P05771	PRKCB	T314	P317L	317	Missense	distal	3	no	1.587	1.200	EPSD	COSMIC	0.942	Down-regulation
AGC_PKC_PKCa_PRKCB_ST	P05771	PRKCB	P05771	PRKCB	T314	G313V	313	Missense	proximal	-1	no	1.587	1.648	EPSD	COSMIC	0.942	Up-regulation
AGC_PKC_PKCa_PRKCB_ST	P05771	PRKCB	P05771	PRKCB	T314	A308T	308	Missense	distal	-6	no	1.587	1.728	EPSD	COSMIC	0.942	Up-regulation
AGC_PKC_PKCa_PRKCB_ST	P05771	PRKCB	P05771	PRKCB	T364	E366K	366	Missense	proximal	2	no	-2.663	2.750	EPSD	COSMIC	0.942	Gain
AGC_PKC_PKCa_PRKCB_ST	P05771	PRKCB	P05771	PRKCB	T500	P505T	505	Missense	distal	5	no	2.613	2.737	EPSD	COSMIC	0.942	Up-regulation
AGC_PKC_PKCa_PRKCB_ST	P05771	PRKCB	P05771	PRKCB	T500	T504I	504	Missense	distal	4	no	2.613	2.783	EPSD	COSMIC	0.942	Up-regulation
AGC_PKC_PKCa_PRKCB_ST	P05771	PRKCB	P05771	PRKCB	T500	T498S	498	Missense	proximal	-2	no	2.613	2.047	EPSD	COSMIC	0.942	Down-regulation
AGC_PKC_PKCa_PRKCB_ST	P05771	PRKCB	P05771	PRKCB	T500	V496M	496	Missense	distal	-4	no	2.613	2.689	EPSD	COSMIC	0.942	Up-regulation
AGC_PKC_PKCa_PRKCB_ST	P05771	PRKCB	P05771	PRKCB	T500	T504N	504	Missense	distal	4	no	2.613	2.969	EPSD	COSMIC	0.942	Up-regulation
AGC_PKC_PKCa_PRKCB_ST	P05771	PRKCB	P05771	PRKCB	S565	A568T	568	Missense	distal	3	no	0.626	1.019	EPSD	COSMIC	0.942	Gain
AGC_PKC_PKCa_PRKCB_ST	P29353	SHC1	P05771	PRKCB	S80	G75R	75	Missense	distal	-5	no	0.879	1.133	EPSD	COSMIC	0.942	Gain
AGC_PKC_PKCa_PRKCB_ST	P29353	SHC1	P05771	PRKCB	S139	T135P	135	Missense	distal	-4	no	3.625	3.771	EPSD;PhosphoSitePlus	COSMIC;GDSC	0.942	Up-regulation
AGC_PKC_PKCa_PRKCB_ST	P29353	SHC1	P05771	PRKCB	S139	R146W	146	Missense	distal	7	no	3.625	3.925	EPSD;PhosphoSitePlus	COSMIC	0.942	Up-regulation
AGC_PKC_PKCa_PRKCB_ST	P29353	SHC1	P05771	PRKCB	T206	R208Q	208	Missense	proximal	2	no	8.391	1.842	EPSD;PhosphoSitePlus	COSMIC	0.942	Down-regulation
AGC_PKC_PKCa_PRKCB_ST	P29353	SHC1	P05771	PRKCB	T206	R208W	208	Missense	proximal	2	no	8.391	-1.122	EPSD;PhosphoSitePlus	COSMIC	0.942	Loss
AGC_PKC_PKCa_PRKCB_ST	P29353	SHC1	P05771	PRKCB	T206	R209K	209	Missense	distal	3	no	8.391	7.935	EPSD;PhosphoSitePlus	COSMIC	0.942	Down-regulation
AGC_PKC_PKCa_PRKCB_ST	P29353	SHC1	P05771	PRKCB	T206	G204E	204	Missense	proximal	-2	no	8.391	8.924	EPSD;PhosphoSitePlus	COSMIC	0.942	Up-regulation
AGC_PKC_PKCa_PRKCB_ST	P29353	SHC1	P05771	PRKCB	S213	R208Q	208	Missense	distal	-5	no	4.082	4.064	PhosphoSitePlus;EPSD	COSMIC	0.942	Down-regulation
AGC_PKC_PKCa_PRKCB_ST	P29353	SHC1	P05771	PRKCB	S213	R208W	208	Missense	distal	-5	no	4.082	3.703	PhosphoSitePlus;EPSD	COSMIC	0.942	Down-regulation
AGC_PKC_PKCa_PRKCB_ST	P29353	SHC1	P05771	PRKCB	S213	L220M	220	Missense	distal	7	no	4.082	4.080	PhosphoSitePlus;EPSD	COSMIC	0.942	Down-regulation
AGC_PKC_PKCa_PRKCB_ST	P29353	SHC1	P05771	PRKCB	S213	P215L	215	Missense	proximal	2	no	4.082	3.282	PhosphoSitePlus;EPSD	COSMIC;GDSC	0.942	Down-regulation
AGC_PKC_PKCa_PRKCB_ST	P29353	SHC1	P05771	PRKCB	S213	R209K	209	Missense	distal	-4	no	4.082	4.027	PhosphoSitePlus;EPSD	COSMIC	0.942	Down-regulation
AGC_PKC_PKCa_PRKCB_ST	P29353	SHC1	P05771	PRKCB	S494	S494R	494	Missense	central	0	yes	3.584	0.000	EPSD	COSMIC	0.942	Loss
AGC_PKC_PKCa_PRKCB_ST	P29353	SHC1	P05771	PRKCB	S494	P487L	487	Missense	distal	-7	no	3.584	3.452	EPSD	COSMIC	0.942	Down-regulation
AGC_PKC_PKCa_PRKCB_ST	P29353	SHC1	P05771	PRKCB	S494	F489L	489	Missense	distal	-5	no	3.584	3.548	EPSD	COSMIC	0.942	Down-regulation
AGC_PKC_PKCa_PRKCB_ST	P29353	SHC1	P05771	PRKCB	S513	R511W	511	Missense	proximal	-2	no	2.977	-0.299	EPSD	COSMIC	0.942	Loss
AGC_PKC_PKCa_PRKCB_ST	Q03721	KCNC4	P05771	PRKCB	S21	E28K	28	Missense	distal	7	no	4.869	4.848	EPSD;PhosphoSitePlus	COSMIC	0.942	Down-regulation
AGC_PKC_PKCa_PRKCB_ST	Q03721	KCNC4	P05771	PRKCB	T49	T45M	45	Missense	distal	-4	no	4.661	4.699	EPSD	COSMIC	0.942	Up-regulation
AGC_PKC_PKCa_PRKCB_ST	Q03721	KCNC4	P05771	PRKCB	S514	C508Y	508	Missense	distal	-6	no	3.036	3.196	EPSD	COSMIC;GDSC;CCLE	0.942	Up-regulation
AGC_PKC_PKCa_PRKCB_ST	Q03721	KCNC4	P05771	PRKCB	T578	D581H	581	Missense	distal	3	no	7.188	7.041	EPSD	COSMIC	0.942	Down-regulation
AGC_PKC_PKCa_PRKCB_ST	Q03721	KCNC4	P05771	PRKCB	T578	R580Q	580	Missense	proximal	2	no	7.188	0.639	EPSD	COSMIC	0.942	Loss
AGC_PKC_PKCa_PRKCB_ST	P15336	ATF2	P05771	PRKCB	S100	M107I	107	Missense	distal	7	no	5.803	5.744	EPSD	COSMIC;GDSC;CCLE	0.942	Down-regulation
AGC_PKC_PKCa_PRKCB_ST	P15336	ATF2	P05771	PRKCB	S100	K105T	105	Missense	distal	5	no	5.803	5.402	EPSD	COSMIC;GDSC;CCLE	0.942	Down-regulation
AGC_PKC_PKCa_PRKCB_ST	P15336	ATF2	P05771	PRKCB	S100	K106R	106	Missense	distal	6	no	5.803	5.652	EPSD	COSMIC	0.942	Down-regulation
AGC_PKC_PKCa_PRKCB_ST	P15336	ATF2	P05771	PRKCB	T253	S257R	257	Missense	distal	4	no	0.009	1.027	EPSD	COSMIC	0.942	Gain
AGC_PKC_PKCa_PRKCB_ST	P15336	ATF2	P05771	PRKCB	S314	R311Q	311	Missense	distal	-3	no	1.491	-1.707	EPSD	COSMIC;GDSC;CCLE	0.942	Loss
AGC_PKC_PKCa_PRKCB_ST	P15336	ATF2	P05771	PRKCB	S314	Q316K	316	Missense	proximal	2	no	1.491	6.417	EPSD	COSMIC	0.942	Up-regulation
AGC_PKC_PKCa_PRKCB_ST	P15336	ATF2	P05771	PRKCB	S314	Q317H	317	Missense	distal	3	no	1.491	1.250	EPSD	COSMIC	0.942	Down-regulation
AGC_PKC_PKCa_PRKCB_ST	P15336	ATF2	P05771	PRKCB	S340	Q337K	337	Missense	distal	-3	no	2.871	6.301	EPSD	COSMIC	0.942	Up-regulation
AGC_PKC_PKCa_PRKCB_ST	P15336	ATF2	P05771	PRKCB	S340	Q335H	335	Missense	distal	-5	no	2.871	2.641	EPSD	COSMIC	0.942	Down-regulation
AGC_PKC_PKCa_PRKCB_ST	P15336	ATF2	P05771	PRKCB	S340	R343L	343	Missense	distal	3	no	2.871	1.786	EPSD	COSMIC	0.942	Down-regulation
AGC_PKC_PKCa_PRKCB_ST	P15336	ATF2	P05771	PRKCB	S340	P334S	334	Missense	distal	-6	no	2.871	2.985	EPSD	COSMIC	0.942	Up-regulation
AGC_PKC_PKCa_PRKCB_ST	P15336	ATF2	P05771	PRKCB	S340	R345T	345	Missense	distal	5	no	2.871	2.531	EPSD	COSMIC	0.942	Down-regulation
AGC_PKC_PKCa_PRKCB_ST	P15336	ATF2	P05771	PRKCB	S340	R343Q	343	Missense	distal	3	no	2.871	2.307	EPSD	COSMIC	0.942	Down-regulation
AGC_PKC_PKCa_PRKCB_ST	P15336	ATF2	P05771	PRKCB	S340	A347T	347	Missense	distal	7	no	2.871	2.781	EPSD	COSMIC	0.942	Down-regulation
AGC_PKC_PKCa_PRKCB_ST	P15336	ATF2	P05771	PRKCB	S340	R345K	345	Missense	distal	5	no	2.871	2.933	EPSD	COSMIC	0.942	Up-regulation
AGC_PKC_PKCa_PRKCB_ST	P15336	ATF2	P05771	PRKCB	S367	A364T	364	Missense	distal	-3	no	0.774	2.220	EPSD	COSMIC	0.942	Gain
AGC_PKC_PKCa_PRKCB_ST	P15336	ATF2	P05771	PRKCB	S367	A365T	365	Missense	proximal	-2	no	0.774	1.179	EPSD	COSMIC	0.942	Gain
AGC_PKC_PKCa_PRKCB_ST	Q06124	PTPN11	P05771	PRKCB	S28	P33S	33	Missense	distal	5	no	0.909	0.966	EPSD	COSMIC	0.942	Gain
AGC_PKC_PKCa_PRKCB_ST	Q06124	PTPN11	P05771	PRKCB	S140	E139K	139	Missense	proximal	-1	no	1.121	1.265	EPSD	COSMIC	0.942	Up-regulation
AGC_PKC_PKCa_PRKCB_ST	Q06124	PTPN11	P05771	PRKCB	S140	G133D	133	Missense	distal	-7	no	1.121	0.851	EPSD	COSMIC	0.942	Loss
AGC_PKC_PKCa_PRKCB_ST	Q06124	PTPN11	P05771	PRKCB	S140	G133C	133	Missense	distal	-7	no	1.121	0.984	EPSD	COSMIC	0.942	Down-regulation
AGC_PKC_PKCa_PRKCB_ST	Q06124	PTPN11	P05771	PRKCB	S140	R138Q	138	Missense	proximal	-2	no	1.121	0.149	EPSD	COSMIC	0.942	Loss
AGC_PKC_PKCa_PRKCB_ST	Q06124	PTPN11	P05771	PRKCB	S142	E139K	139	Missense	distal	-3	no	-2.308	1.027	EPSD	COSMIC	0.942	Gain
AGC_PKC_PKCa_PRKCB_ST	Q06124	PTPN11	P05771	PRKCB	S160	G163C	163	Missense	distal	3	no	0.985	1.160	EPSD	COSMIC	0.942	Up-regulation
AGC_PKC_PKCa_PRKCB_ST	Q06124	PTPN11	P05771	PRKCB	T397	T397M	397	Missense	central	0	yes	1.295	0.000	EPSD	COSMIC	0.942	Loss
AGC_PKC_PKCa_PRKCB_ST	Q06124	PTPN11	P05771	PRKCB	T397	A392V	392	Missense	distal	-5	no	1.295	1.266	EPSD	COSMIC	0.942	Down-regulation
AGC_PKC_PKCa_PRKCB_ST	Q06124	PTPN11	P05771	PRKCB	T415	E416G	416	Missense	proximal	1	no	1.289	1.058	EPSD	COSMIC	0.942	Down-regulation
AGC_PKC_PKCa_PRKCB_ST	Q06124	PTPN11	P05771	PRKCB	T415	T415M	415	Missense	central	0	yes	1.289	0.000	EPSD	COSMIC	0.942	Loss
AGC_PKC_PKCa_PRKCB_ST	Q06124	PTPN11	P05771	PRKCB	T415	G413W	413	Missense	proximal	-2	no	1.289	-0.120	EPSD	COSMIC	0.942	Loss
AGC_PKC_PKCa_PRKCB_ST	Q06124	PTPN11	P05771	PRKCB	S503	M508V	508	Missense	distal	5	no	3.497	3.523	EPSD	COSMIC	0.942	Up-regulation
AGC_PKC_PKCa_PRKCB_ST	Q06124	PTPN11	P05771	PRKCB	S503	R502W	502	Missense	proximal	-1	no	3.497	2.628	EPSD	COSMIC	0.942	Down-regulation
AGC_PKC_PKCa_PRKCB_ST	Q06124	PTPN11	P05771	PRKCB	S503	S506L	506	Missense	distal	3	no	3.497	3.177	EPSD	COSMIC	0.942	Down-regulation
AGC_PKC_PKCa_PRKCB_ST	Q06124	PTPN11	P05771	PRKCB	S503	V509I	509	Missense	distal	6	no	3.497	3.615	EPSD	COSMIC	0.942	Up-regulation
AGC_PKC_PKCa_PRKCB_ST	Q06124	PTPN11	P05771	PRKCB	S503	Q504E	504	Missense	proximal	1	no	3.497	2.317	EPSD	COSMIC	0.942	Down-regulation
AGC_PKC_PKCa_PRKCB_ST	Q06124	PTPN11	P05771	PRKCB	S503	G507V	507	Missense	distal	4	no	3.497	3.917	EPSD	COSMIC	0.942	Up-regulation
AGC_PKC_PKCa_PRKCB_ST	Q06124	PTPN11	P05771	PRKCB	S503	G507R	507	Missense	distal	4	no	3.497	4.853	EPSD	COSMIC	0.942	Up-regulation
AGC_PKC_PKCa_PRKCB_ST	Q06124	PTPN11	P05771	PRKCB	S503	Q510K	510	Missense	distal	7	no	3.497	3.532	EPSD	COSMIC	0.942	Up-regulation
AGC_PKC_PKCa_PRKCB_ST	Q06124	PTPN11	P05771	PRKCB	S503	R505K	505	Missense	proximal	2	no	3.497	1.874	EPSD	COSMIC	0.942	Down-regulation
AGC_PKC_PKCa_PRKCB_ST	Q06124	PTPN11	P05771	PRKCB	S503	S506P	506	Missense	distal	3	no	3.497	3.564	EPSD	COSMIC	0.942	Up-regulation
AGC_PKC_PKCa_PRKCB_ST	Q06124	PTPN11	P05771	PRKCB	S503	G507E	507	Missense	distal	4	no	3.497	4.148	EPSD	COSMIC	0.942	Up-regulation
AGC_PKC_PKCa_PRKCB_ST	Q06124	PTPN11	P05771	PRKCB	S503	G507A	507	Missense	distal	4	no	3.497	3.365	EPSD	COSMIC	0.942	Down-regulation
AGC_PKC_PKCa_PRKCB_ST	Q06124	PTPN11	P05771	PRKCB	S503	R502Q	502	Missense	proximal	-1	no	3.497	3.312	EPSD	COSMIC	0.942	Down-regulation
AGC_PKC_PKCa_PRKCB_ST	Q06124	PTPN11	P05771	PRKCB	S503	Q510P	510	Missense	distal	7	no	3.497	3.684	EPSD	COSMIC	0.942	Up-regulation
AGC_PKC_PKCa_PRKCB_ST	Q06124	PTPN11	P05771	PRKCB	S503	G507W	507	Missense	distal	4	no	3.497	3.111	EPSD	COSMIC	0.942	Down-regulation
AGC_PKC_PKCa_PRKCB_ST	Q06124	PTPN11	P05771	PRKCB	S503	Q510E	510	Missense	distal	7	no	3.497	3.553	EPSD	COSMIC	0.942	Up-regulation
AGC_PKC_PKCa_PRKCB_ST	Q06124	PTPN11	P05771	PRKCB	S503	S506T	506	Missense	distal	3	no	3.497	3.677	EPSD	COSMIC	0.942	Up-regulation
AGC_PKC_PKCa_PRKCB_ST	Q06124	PTPN11	P05771	PRKCB	S503	S506A	506	Missense	distal	3	no	3.497	3.283	EPSD	COSMIC	0.942	Down-regulation
AGC_PKC_PKCa_PRKCB_ST	Q06124	PTPN11	P05771	PRKCB	S503	R502L	502	Missense	proximal	-1	no	3.497	2.885	EPSD	COSMIC	0.942	Down-regulation
AGC_PKC_PKCa_PRKCB_ST	Q06124	PTPN11	P05771	PRKCB	S503	T497I	497	Missense	distal	-6	no	3.497	3.387	EPSD	COSMIC	0.942	Down-regulation
AGC_PKC_PKCa_PRKCB_ST	Q06124	PTPN11	P05771	PRKCB	S503	M508I	508	Missense	distal	5	no	3.497	3.616	EPSD	COSMIC	0.942	Up-regulation
AGC_PKC_PKCa_PRKCB_ST	Q06124	PTPN11	P05771	PRKCB	S503	G507L	507	Missense	distal	4	no	3.497	3.548	EPSD	COSMIC	0.942	Up-regulation
AGC_PKC_PKCa_PRKCB_ST	Q06124	PTPN11	P05771	PRKCB	S503	S503F	503	Missense	central	0	yes	3.497	0.000	EPSD	COSMIC	0.942	Loss
AGC_PKC_PKCa_PRKCB_ST	Q06124	PTPN11	P05771	PRKCB	S539	E545K	545	Missense	distal	6	no	3.045	3.542	EPSD	COSMIC	0.942	Up-regulation
AGC_PKC_PKCa_PRKCB_ST	Q06124	PTPN11	P05771	PRKCB	S539	E545D	545	Missense	distal	6	no	3.045	2.645	EPSD	COSMIC	0.942	Down-regulation
AGC_PKC_PKCa_PRKCB_ST	Q06124	PTPN11	P05771	PRKCB	S539	I533V	533	Missense	distal	-6	no	3.045	3.081	EPSD	COSMIC	0.942	Up-regulation
AGC_PKC_PKCa_PRKCB_ST	Q06124	PTPN11	P05771	PRKCB	S539	Y546C	546	Missense	distal	7	no	3.045	3.128	EPSD	COSMIC	0.942	Up-regulation
AGC_PKC_PKCa_PRKCB_ST	Q06124	PTPN11	P05771	PRKCB	S539	G543E	543	Missense	distal	4	no	3.045	3.696	EPSD	COSMIC	0.942	Up-regulation
AGC_PKC_PKCa_PRKCB_ST	Q06124	PTPN11	P05771	PRKCB	S580	D579E	579	Missense	proximal	-1	no	9.230	9.316	EPSD	COSMIC	0.942	Up-regulation
AGC_PKC_PKCa_PRKCB_ST	Q06124	PTPN11	P05771	PRKCB	S580	R582G	582	Missense	proximal	2	no	9.230	0.496	EPSD	COSMIC	0.942	Loss
AGC_PKC_PKCa_PRKCB_ST	Q06124	PTPN11	P05771	PRKCB	S580	V583A	583	Missense	distal	3	no	9.230	9.385	EPSD	COSMIC	0.942	Up-regulation
AGC_PKC_PKCa_PRKCB_ST	Q06124	PTPN11	P05771	PRKCB	S580	V587A	587	Missense	distal	7	no	9.230	9.285	EPSD	COSMIC	0.942	Up-regulation
AGC_PKC_PKCa_PRKCB_ST	Q06124	PTPN11	P05771	PRKCB	S580	S580I	580	Missense	central	0	yes	9.230	0.000	EPSD	COSMIC	0.942	Loss
AGC_PKC_PKCa_PRKCB_ST	Q06124	PTPN11	P05771	PRKCB	S595	Q592H	592	Missense	distal	-3	no	7.313	7.525	EPSD	COSMIC	0.942	Up-regulation
AGC_PKC_PKCa_PRKCB_ST	Q06124	PTPN11	P05771	PRKCB	S595	K594R	594	Missense	proximal	-1	no	7.313	7.489	EPSD	COSMIC	0.942	Up-regulation
AGC_PKC_PKCa_PRKCB_ST	P49841	GSK3B	P05771	PRKCB	S2	S9F	9	Missense	distal	7	no	3.927	3.985	EPSD	COSMIC	0.942	Up-regulation
AGC_PKC_PKCa_PRKCB_ST	P49841	GSK3B	P05771	PRKCB	S2	S2P	2	Missense	central	0	yes	3.927	0.000	EPSD	COSMIC	0.942	Loss
AGC_PKC_PKCa_PRKCB_ST	P49841	GSK3B	P05771	PRKCB	S9	S9F	9	Missense	central	0	yes	2.332	0.000	PhosphoSitePlus	COSMIC	0.942	Loss
AGC_PKC_PKCa_PRKCB_ST	P49841	GSK3B	P05771	PRKCB	S9	P16A	16	Missense	distal	7	no	2.332	2.356	PhosphoSitePlus	COSMIC	0.942	Up-regulation
AGC_PKC_PKCa_PRKCB_ST	P49841	GSK3B	P05771	PRKCB	S9	S2P	2	Missense	distal	-7	no	2.332	2.457	PhosphoSitePlus	COSMIC	0.942	Up-regulation
AGC_PKC_PKCa_PRKCB_ST	P49841	GSK3B	P05771	PRKCB	S13	S9F	9	Missense	distal	-4	no	1.665	1.643	EPSD	COSMIC	0.942	Down-regulation
AGC_PKC_PKCa_PRKCB_ST	P49841	GSK3B	P05771	PRKCB	S13	P16A	16	Missense	distal	3	no	1.665	1.385	EPSD	COSMIC	0.942	Down-regulation
AGC_PKC_PKCa_PRKCB_ST	P49841	GSK3B	P05771	PRKCB	S25	A22T	22	Missense	distal	-3	no	0.733	2.179	EPSD	COSMIC	0.942	Gain
AGC_PKC_PKCa_PRKCB_ST	P49841	GSK3B	P05771	PRKCB	S29	S35R	35	Missense	distal	6	no	0.028	0.998	EPSD	COSMIC	0.942	Gain
AGC_PKC_PKCa_PRKCB_ST	P49841	GSK3B	P05771	PRKCB	S35	D31Y	31	Missense	distal	-4	no	2.853	2.734	EPSD	COSMIC	0.942	Down-regulation
AGC_PKC_PKCa_PRKCB_ST	P49841	GSK3B	P05771	PRKCB	S35	D33N	33	Missense	proximal	-2	no	2.853	3.378	EPSD	COSMIC	0.942	Up-regulation
AGC_PKC_PKCa_PRKCB_ST	P49841	GSK3B	P05771	PRKCB	S35	S35R	35	Missense	central	0	yes	2.853	0.000	EPSD	COSMIC	0.942	Loss
AGC_PKC_PKCa_PRKCB_ST	P49841	GSK3B	P05771	PRKCB	S35	V41G	41	Missense	distal	6	no	2.853	2.679	EPSD	COSMIC	0.942	Down-regulation
AGC_PKC_PKCa_PRKCB_ST	P49841	GSK3B	P05771	PRKCB	S35	V37G	37	Missense	proximal	2	no	2.853	-0.578	EPSD	COSMIC	0.942	Loss
AGC_PKC_PKCa_PRKCB_ST	P49841	GSK3B	P05771	PRKCB	S35	D33G	33	Missense	proximal	-2	no	2.853	3.233	EPSD	COSMIC;GDSC;CCLE	0.942	Up-regulation
AGC_PKC_PKCa_PRKCB_ST	P49841	GSK3B	P05771	PRKCB	S35	D33H	33	Missense	proximal	-2	no	2.853	3.085	EPSD	COSMIC	0.942	Up-regulation
AGC_PKC_PKCa_PRKCB_ST	P49841	GSK3B	P05771	PRKCB	S203	Q206K	206	Missense	distal	3	no	2.951	3.059	EPSD	COSMIC	0.942	Up-regulation
AGC_PKC_PKCa_PRKCB_ST	P49841	GSK3B	P05771	PRKCB	S203	L196V	196	Missense	distal	-7	no	2.951	2.964	EPSD	COSMIC	0.942	Up-regulation
AGC_PKC_PKCa_PRKCB_ST	P07355	ANXA2	P05771	PRKCB	S26	K28Q	28	Missense	proximal	2	no	2.460	-2.466	PhosphoSitePlus	COSMIC;CCLE	0.942	Loss
AGC_PKC_PKCa_PRKCB_ST	P07355	ANXA2	P05771	PRKCB	S277	R273L	273	Missense	distal	-4	no	1.315	1.699	EPSD	COSMIC	0.942	Up-regulation
AGC_PKC_PKCa_PRKCB_ST	P07355	ANXA2	P05771	PRKCB	S277	T283M	283	Missense	distal	6	no	1.315	1.151	EPSD	COSMIC	0.942	Down-regulation
AGC_PKC_PKCa_PRKCB_ST	P07355	ANXA2	P05771	PRKCB	S277	R284L	284	Missense	distal	7	no	1.315	1.546	EPSD	COSMIC	0.942	Up-regulation
AGC_PKC_PKCa_PRKCB_ST	Q96D31	ORAI1	P05771	PRKCB	S12	S13R	13	Missense	proximal	1	no	-0.305	1.719	EPSD	COSMIC	0.942	Gain
AGC_PKC_PKCa_PRKCB_ST	Q96D31	ORAI1	P05771	PRKCB	S34	G41R	41	Missense	distal	7	no	3.160	2.859	EPSD	COSMIC	0.942	Down-regulation
AGC_PKC_PKCa_PRKCB_ST	Q96D31	ORAI1	P05771	PRKCB	S159	S159L	159	Missense	central	0	yes	4.287	0.000	EPSD	COSMIC	0.942	Loss
AGC_PKC_PKCa_PRKCB_ST	Q96D31	ORAI1	P05771	PRKCB	S159	P164H	164	Missense	distal	5	no	4.287	4.374	EPSD	COSMIC	0.942	Up-regulation
AGC_PKC_PKCa_PRKCB_ST	Q16625	OCLN	P05771	PRKCB	S2	R4W	4	Missense	proximal	2	no	3.990	-5.523	EPSD	COSMIC	0.942	Loss
AGC_PKC_PKCa_PRKCB_ST	Q16625	OCLN	P05771	PRKCB	S166	S159R	159	Missense	distal	-7	no	1.749	1.479	EPSD	COSMIC	0.942	Down-regulation
AGC_PKC_PKCa_PRKCB_ST	Q16625	OCLN	P05771	PRKCB	S166	V160I	160	Missense	distal	-6	no	1.749	1.714	EPSD	COSMIC	0.942	Down-regulation
AGC_PKC_PKCa_PRKCB_ST	Q16625	OCLN	P05771	PRKCB	S166	L173F	173	Missense	distal	7	no	1.749	1.747	EPSD	COSMIC	0.942	Down-regulation
AGC_PKC_PKCa_PRKCB_ST	Q16625	OCLN	P05771	PRKCB	S166	R162I	162	Missense	distal	-4	no	1.749	2.045	EPSD	COSMIC	0.942	Up-regulation
AGC_PKC_PKCa_PRKCB_ST	Q16625	OCLN	P05771	PRKCB	S378	G372D	372	Missense	distal	-6	no	6.257	6.427	EPSD	COSMIC	0.942	Up-regulation
AGC_PKC_PKCa_PRKCB_ST	Q9UBS0	RPS6KB2	P05771	PRKCB	T228	A224T	224	Missense	distal	-4	no	1.590	1.486	EPSD	COSMIC	0.942	Down-regulation
AGC_PKC_PKCa_PRKCB_ST	Q9UBS0	RPS6KB2	P05771	PRKCB	T228	V225F	225	Missense	distal	-3	no	1.590	0.622	EPSD	COSMIC	0.942	Loss
AGC_PKC_PKCa_PRKCB_ST	Q9UBS0	RPS6KB2	P05771	PRKCB	S410	R413C	413	Missense	distal	3	no	7.610	6.757	EPSD	COSMIC	0.942	Down-regulation
AGC_PKC_PKCa_PRKCB_ST	Q9UBS0	RPS6KB2	P05771	PRKCB	S410	R413H	413	Missense	distal	3	no	7.610	6.805	EPSD	COSMIC	0.942	Down-regulation
AGC_PKC_PKCa_PRKCB_ST	Q9UBS0	RPS6KB2	P05771	PRKCB	S417	P421S	421	Missense	distal	4	no	1.767	1.633	EPSD	COSMIC	0.942	Down-regulation
AGC_PKC_PKCa_PRKCB_ST	Q9UBS0	RPS6KB2	P05771	PRKCB	S417	R413C	413	Missense	distal	-4	no	1.767	2.273	EPSD	COSMIC	0.942	Up-regulation
AGC_PKC_PKCa_PRKCB_ST	Q9UBS0	RPS6KB2	P05771	PRKCB	S417	R413H	413	Missense	distal	-4	no	1.767	2.074	EPSD	COSMIC	0.942	Up-regulation
AGC_PKC_PKCa_PRKCB_ST	Q9UBS0	RPS6KB2	P05771	PRKCB	S417	P421L	421	Missense	distal	4	no	1.767	1.345	EPSD	COSMIC	0.942	Down-regulation
AGC_PKC_PKCa_PRKCB_ST	Q9UBS0	RPS6KB2	P05771	PRKCB	S417	P424L	424	Missense	distal	7	no	1.767	1.735	EPSD	COSMIC	0.942	Down-regulation
AGC_PKC_PKCa_PRKCB_ST	Q9UBS0	RPS6KB2	P05771	PRKCB	S436	T443M	443	Missense	distal	7	no	0.912	0.944	EPSD	COSMIC	0.942	Gain
AGC_PKC_PKCa_PRKCB_ST	Q9UBS0	RPS6KB2	P05771	PRKCB	S468	S468P	468	Missense	central	0	yes	3.257	0.000	EPSD	COSMIC	0.942	Loss
AGC_PKC_PKCa_PRKCB_ST	Q9UBS0	RPS6KB2	P05771	PRKCB	S468	P463S	463	Missense	distal	-5	no	3.257	3.282	EPSD	COSMIC	0.942	Up-regulation
AGC_PKC_PKCa_PRKCB_ST	Q9UBS0	RPS6KB2	P05771	PRKCB	S468	R475G	475	Missense	distal	7	no	3.257	3.557	EPSD	COSMIC	0.942	Up-regulation
AGC_PKC_PKCa_PRKCB_ST	Q9UBS0	RPS6KB2	P05771	PRKCB	S468	P467H	467	Missense	proximal	-1	no	3.257	3.438	EPSD	COSMIC	0.942	Up-regulation
AGC_PKC_PKCa_PRKCB_ST	Q9UBS0	RPS6KB2	P05771	PRKCB	S468	R465H	465	Missense	distal	-3	no	3.257	0.270	EPSD	COSMIC	0.942	Loss
AGC_PKC_PKCa_PRKCB_ST	Q9UBS0	RPS6KB2	P05771	PRKCB	T470	S468P	468	Missense	proximal	-2	no	1.712	1.833	EPSD	COSMIC	0.942	Up-regulation
AGC_PKC_PKCa_PRKCB_ST	Q9UBS0	RPS6KB2	P05771	PRKCB	T470	P463S	463	Missense	distal	-7	no	1.712	1.587	EPSD	COSMIC	0.942	Down-regulation
AGC_PKC_PKCa_PRKCB_ST	Q9UBS0	RPS6KB2	P05771	PRKCB	T470	R477H	477	Missense	distal	7	no	1.712	1.938	EPSD	COSMIC	0.942	Up-regulation
AGC_PKC_PKCa_PRKCB_ST	Q9UBS0	RPS6KB2	P05771	PRKCB	T470	R475G	475	Missense	distal	5	no	1.712	1.283	EPSD	COSMIC	0.942	Down-regulation
AGC_PKC_PKCa_PRKCB_ST	Q9UBS0	RPS6KB2	P05771	PRKCB	T470	P467H	467	Missense	distal	-3	no	1.712	1.938	EPSD	COSMIC	0.942	Up-regulation
AGC_PKC_PKCa_PRKCB_ST	Q9UBS0	RPS6KB2	P05771	PRKCB	T470	R465H	465	Missense	distal	-5	no	1.712	1.465	EPSD	COSMIC	0.942	Down-regulation
AGC_PKC_PKCa_PRKCB_ST	Q9UBS0	RPS6KB2	P05771	PRKCB	S473	R479H	479	Missense	distal	6	no	10.091	9.331	PhosphoSitePlus	COSMIC;CCLE	0.942	Down-regulation
AGC_PKC_PKCa_PRKCB_ST	Q9UBS0	RPS6KB2	P05771	PRKCB	S473	S468P	468	Missense	distal	-5	no	10.091	10.065	PhosphoSitePlus	COSMIC	0.942	Down-regulation
AGC_PKC_PKCa_PRKCB_ST	Q9UBS0	RPS6KB2	P05771	PRKCB	S473	P480Q	480	Missense	distal	7	no	10.091	9.904	PhosphoSitePlus	COSMIC	0.942	Down-regulation
AGC_PKC_PKCa_PRKCB_ST	Q9UBS0	RPS6KB2	P05771	PRKCB	S473	R477H	477	Missense	distal	4	no	10.091	9.269	PhosphoSitePlus	COSMIC	0.942	Down-regulation
AGC_PKC_PKCa_PRKCB_ST	Q9UBS0	RPS6KB2	P05771	PRKCB	S473	R475G	475	Missense	proximal	2	no	10.091	1.357	PhosphoSitePlus	COSMIC	0.942	Down-regulation
AGC_PKC_PKCa_PRKCB_ST	Q9UBS0	RPS6KB2	P05771	PRKCB	S473	P467H	467	Missense	distal	-6	no	10.091	10.173	PhosphoSitePlus	COSMIC	0.942	Up-regulation
AGC_PKC_PKCa_PRKCB_ST	P35548	MSX2	P05771	PRKCB	S44	S43F	43	Missense	proximal	-1	no	1.972	2.122	EPSD	COSMIC	0.942	Up-regulation
AGC_PKC_PKCa_PRKCB_ST	O15519	CFLAR	P05771	PRKCB	S193	P197T	197	Missense	distal	4	no	3.351	3.188	PhosphoSitePlus	COSMIC	0.942	Down-regulation
AGC_PKC_PKCa_PRKCB_ST	O15519	CFLAR	P05771	PRKCB	S193	A189T	189	Missense	distal	-4	no	3.351	3.246	PhosphoSitePlus	COSMIC	0.942	Down-regulation
AGC_PKC_PKCa_PRKCB_ST	O15519	CFLAR	P05771	PRKCB	S248	S248L	248	Missense	central	0	yes	1.767	0.000	EPSD	COSMIC;GDSC	0.942	Loss
AGC_PKC_PKCa_PRKCB_ST	O15519	CFLAR	P05771	PRKCB	S248	P250A	250	Missense	proximal	2	no	1.767	-0.400	EPSD	COSMIC	0.942	Loss
AGC_PKC_PKCa_PRKCB_ST	P48736	PIK3CG	P05771	PRKCB	S227	T229N	229	Missense	proximal	2	no	1.324	0.689	EPSD	COSMIC	0.942	Loss
AGC_PKC_PKCa_PRKCB_ST	P48736	PIK3CG	P05771	PRKCB	S227	T229S	229	Missense	proximal	2	no	1.324	-0.030	EPSD	COSMIC	0.942	Loss
AGC_PKC_PKCa_PRKCB_ST	P48736	PIK3CG	P05771	PRKCB	S227	R226G	226	Missense	proximal	-1	no	1.324	0.791	EPSD	COSMIC	0.942	Loss
AGC_PKC_PKCa_PRKCB_ST	P48736	PIK3CG	P05771	PRKCB	S227	R226L	226	Missense	proximal	-1	no	1.324	0.712	EPSD	COSMIC	0.942	Loss
AGC_PKC_PKCa_PRKCB_ST	P48736	PIK3CG	P05771	PRKCB	S227	R226C	226	Missense	proximal	-1	no	1.324	0.620	EPSD	COSMIC	0.942	Loss
AGC_PKC_PKCa_PRKCB_ST	P48736	PIK3CG	P05771	PRKCB	S227	I233F	233	Missense	distal	6	no	1.324	1.072	EPSD	COSMIC	0.942	Down-regulation
AGC_PKC_PKCa_PRKCB_ST	P48736	PIK3CG	P05771	PRKCB	S227	T228N	228	Missense	proximal	1	no	1.324	0.478	EPSD	COSMIC	0.942	Loss
AGC_PKC_PKCa_PRKCB_ST	P48736	PIK3CG	P05771	PRKCB	S227	T232N	232	Missense	distal	5	no	1.324	1.352	EPSD	COSMIC	0.942	Up-regulation
AGC_PKC_PKCa_PRKCB_ST	P48736	PIK3CG	P05771	PRKCB	S417	D422Y	422	Missense	distal	5	no	3.333	3.209	EPSD	COSMIC	0.942	Down-regulation
AGC_PKC_PKCa_PRKCB_ST	P48736	PIK3CG	P05771	PRKCB	S417	N411H	411	Missense	distal	-6	no	3.333	3.205	EPSD	COSMIC	0.942	Down-regulation
AGC_PKC_PKCa_PRKCB_ST	P48736	PIK3CG	P05771	PRKCB	S417	E415K	415	Missense	proximal	-2	no	3.333	4.777	EPSD	COSMIC	0.942	Up-regulation
AGC_PKC_PKCa_PRKCB_ST	P48736	PIK3CG	P05771	PRKCB	S417	V412L	412	Missense	distal	-5	no	3.333	3.314	EPSD	COSMIC	0.942	Down-regulation
AGC_PKC_PKCa_PRKCB_ST	P48736	PIK3CG	P05771	PRKCB	S582	H577N	577	Missense	distal	-5	no	6.675	6.718	PhosphoSitePlus	COSMIC	0.942	Up-regulation
AGC_PKC_PKCa_PRKCB_ST	P48736	PIK3CG	P05771	PRKCB	S582	F578L	578	Missense	distal	-4	no	6.675	6.756	PhosphoSitePlus	COSMIC	0.942	Up-regulation
AGC_PKC_PKCa_PRKCB_ST	P48736	PIK3CG	P05771	PRKCB	S582	L583F	583	Missense	proximal	1	no	6.675	7.176	PhosphoSitePlus	COSMIC	0.942	Up-regulation
AGC_PKC_PKCa_PRKCB_ST	P48736	PIK3CG	P05771	PRKCB	S582	K587T	587	Missense	distal	5	no	6.675	6.274	PhosphoSitePlus	COSMIC	0.942	Down-regulation
AGC_PKC_PKCa_PRKCB_ST	P48736	PIK3CG	P05771	PRKCB	S582	A588V	588	Missense	distal	6	no	6.675	6.751	PhosphoSitePlus	COSMIC	0.942	Up-regulation
AGC_PKC_PKCa_PRKCB_ST	P21730	C5AR1	P05771	PRKCB	S327	E331K	331	Missense	distal	4	no	1.648	2.239	EPSD	COSMIC	0.942	Up-regulation
AGC_PKC_PKCa_PRKCB_ST	P21730	C5AR1	P05771	PRKCB	S332	E331K	331	Missense	proximal	-1	no	1.111	1.254	EPSD	COSMIC	0.942	Up-regulation
AGC_PKC_PKCa_PRKCB_ST	P21730	C5AR1	P05771	PRKCB	S332	T336M	336	Missense	distal	4	no	1.111	1.170	EPSD	COSMIC	0.942	Up-regulation
AGC_PKC_PKCa_PRKCB_ST	P21730	C5AR1	P05771	PRKCB	S334	E331K	331	Missense	distal	-3	no	0.990	4.325	PhosphoSitePlus	COSMIC	0.942	Up-regulation
AGC_PKC_PKCa_PRKCB_ST	P21730	C5AR1	P05771	PRKCB	S334	T336M	336	Missense	proximal	2	no	0.990	-1.128	PhosphoSitePlus	COSMIC	0.942	Loss
AGC_PKC_PKCa_PRKCB_ST	P31749	AKT1	P05771	PRKCB	T65	L62R	62	Missense	distal	-3	no	-0.093	4.064	EPSD	COSMIC	0.942	Gain
AGC_PKC_PKCa_PRKCB_ST	P31749	AKT1	P05771	PRKCB	S124	G123D	123	Missense	proximal	-1	no	0.937	1.063	EPSD	COSMIC	0.942	Gain
AGC_PKC_PKCa_PRKCB_ST	P31749	AKT1	P05771	PRKCB	S124	D127N	127	Missense	distal	3	no	0.937	0.992	EPSD	COSMIC	0.942	Gain
AGC_PKC_PKCa_PRKCB_ST	P31749	AKT1	P05771	PRKCB	S124	G130R	130	Missense	distal	6	no	0.937	2.363	EPSD	COSMIC	0.942	Gain
AGC_PKC_PKCa_PRKCB_ST	P31749	AKT1	P05771	PRKCB	S246	A250V	250	Missense	distal	4	no	0.465	1.017	EPSD	COSMIC	0.942	Gain
AGC_PKC_PKCa_PRKCB_ST	P31749	AKT1	P05771	PRKCB	T308	M306T	306	Missense	proximal	-2	no	1.425	2.076	EPSD;PhosphoSitePlus	COSMIC	0.942	Up-regulation
AGC_PKC_PKCa_PRKCB_ST	P31749	AKT1	P05771	PRKCB	T308	M306L	306	Missense	proximal	-2	no	1.425	0.944	EPSD;PhosphoSitePlus	COSMIC	0.942	Down-regulation
AGC_PKC_PKCa_PRKCB_ST	P31749	AKT1	P05771	PRKCB	T308	M306I	306	Missense	proximal	-2	no	1.425	1.913	EPSD;PhosphoSitePlus	COSMIC	0.942	Up-regulation
AGC_PKC_PKCa_PRKCB_ST	P31749	AKT1	P05771	PRKCB	T308	T312I	312	Missense	distal	4	no	1.425	1.595	EPSD;PhosphoSitePlus	COSMIC	0.942	Up-regulation
AGC_PKC_PKCa_PRKCB_ST	P31749	AKT1	P05771	PRKCB	T308	G303S	303	Missense	distal	-5	no	1.425	1.432	EPSD;PhosphoSitePlus	COSMIC	0.942	Up-regulation
AGC_PKC_PKCa_PRKCB_ST	P31749	AKT1	P05771	PRKCB	S422	V416M	416	Missense	distal	-6	no	2.176	2.146	EPSD	COSMIC	0.942	Down-regulation
AGC_PKC_PKCa_PRKCB_ST	P31749	AKT1	P05771	PRKCB	S422	S422R	422	Missense	central	0	yes	2.176	0.000	EPSD	COSMIC	0.942	Loss
AGC_PKC_PKCa_PRKCB_ST	Q9P2D0	IBTK	P05771	PRKCB	S765	C764S	764	Missense	proximal	-1	no	2.408	2.508	EPSD	COSMIC	0.942	Up-regulation
AGC_PKC_PKCa_PRKCB_ST	Q9P2D0	IBTK	P05771	PRKCB	S765	D769E	769	Missense	distal	4	no	2.408	2.646	EPSD	COSMIC	0.942	Up-regulation
AGC_PKC_PKCa_PRKCB_ST	Q9P2D0	IBTK	P05771	PRKCB	S990	N997S	997	Missense	distal	7	no	1.520	1.537	EPSD	COSMIC;GDSC;CCLE	0.942	Up-regulation
AGC_PKC_PKCa_PRKCB_ST	Q9P2D0	IBTK	P05771	PRKCB	S990	R987C	987	Missense	distal	-3	no	1.520	-2.380	EPSD	COSMIC	0.942	Loss
AGC_PKC_PKCa_PRKCB_ST	Q9P2D0	IBTK	P05771	PRKCB	S1096	R1098T	1098	Missense	proximal	2	no	1.943	-2.700	EPSD	COSMIC	0.942	Loss
AGC_PKC_PKCa_PRKCB_ST	Q9P2D0	IBTK	P05771	PRKCB	S1154	S1154Y	1154	Missense	central	0	yes	9.095	0.000	EPSD	COSMIC	0.942	Loss
AGC_PKC_PKCa_PRKCB_ST	Q9P2D0	IBTK	P05771	PRKCB	S1154	H1149N	1149	Missense	distal	-5	no	9.095	9.138	EPSD	COSMIC	0.942	Up-regulation
AGC_PKC_PKCa_PRKCB_ST	Q9P2D0	IBTK	P05771	PRKCB	S1203	L1209P	1209	Missense	distal	6	no	2.615	3.317	EPSD;PhosphoSitePlus	COSMIC;GDSC;CCLE	0.942	Up-regulation
AGC_PKC_PKCa_PRKCB_ST	Q9UH77	KLHL3	P05771	PRKCB	S10	E4K	4	Missense	distal	-6	no	2.790	2.935	EPSD	COSMIC	0.942	Up-regulation
AGC_PKC_PKCa_PRKCB_ST	Q9UH77	KLHL3	P05771	PRKCB	S433	G435R	435	Missense	proximal	2	no	-1.035	7.699	PhosphoSitePlus	COSMIC	0.942	Gain
AGC_PKC_PKCa_PRKCB_ST	P35568	IRS1	P05771	PRKCB	S24	K27R	27	Missense	distal	3	no	1.120	1.577	EPSD	COSMIC	0.942	Up-regulation
AGC_PKC_PKCa_PRKCB_ST	P35568	IRS1	P05771	PRKCB	S24	V31I	31	Missense	distal	7	no	1.120	1.058	EPSD	COSMIC	0.942	Down-regulation
AGC_PKC_PKCa_PRKCB_ST	P35568	IRS1	P05771	PRKCB	S24	G17C	17	Missense	distal	-7	no	1.120	0.984	EPSD	COSMIC	0.942	Down-regulation
AGC_PKC_PKCa_PRKCB_ST	P35568	IRS1	P05771	PRKCB	S193	K190N	190	Missense	distal	-3	no	2.556	-0.606	EPSD	COSMIC	0.942	Loss
AGC_PKC_PKCa_PRKCB_ST	P35568	IRS1	P05771	PRKCB	S193	S189N	189	Missense	distal	-4	no	2.556	2.538	EPSD	COSMIC	0.942	Down-regulation
AGC_PKC_PKCa_PRKCB_ST	P35568	IRS1	P05771	PRKCB	S268	R265C	265	Missense	distal	-3	no	3.296	-0.603	EPSD	COSMIC	0.942	Loss
AGC_PKC_PKCa_PRKCB_ST	P35568	IRS1	P05771	PRKCB	S268	S274P	274	Missense	distal	6	no	3.296	3.709	EPSD	COSMIC	0.942	Up-regulation
AGC_PKC_PKCa_PRKCB_ST	P35568	IRS1	P05771	PRKCB	S272	R265C	265	Missense	distal	-7	no	1.748	1.964	EPSD	COSMIC	0.942	Up-regulation
AGC_PKC_PKCa_PRKCB_ST	P35568	IRS1	P05771	PRKCB	S272	S274P	274	Missense	proximal	2	no	1.748	1.913	EPSD	COSMIC	0.942	Up-regulation
AGC_PKC_PKCa_PRKCB_ST	P35568	IRS1	P05771	PRKCB	S273	S274P	274	Missense	proximal	1	no	1.684	1.887	EPSD	COSMIC	0.942	Up-regulation
AGC_PKC_PKCa_PRKCB_ST	P35568	IRS1	P05771	PRKCB	S303	R301C	301	Missense	proximal	-2	no	4.483	3.017	EPSD	COSMIC	0.942	Down-regulation
AGC_PKC_PKCa_PRKCB_ST	P35568	IRS1	P05771	PRKCB	S303	Q296R	296	Missense	distal	-7	no	4.483	4.458	EPSD	COSMIC;GDSC	0.942	Down-regulation
AGC_PKC_PKCa_PRKCB_ST	P35568	IRS1	P05771	PRKCB	S303	E306K	306	Missense	distal	3	no	4.483	4.431	EPSD	COSMIC	0.942	Down-regulation
AGC_PKC_PKCa_PRKCB_ST	P35568	IRS1	P05771	PRKCB	S303	A310T	310	Missense	distal	7	no	4.483	4.392	EPSD	COSMIC	0.942	Down-regulation
AGC_PKC_PKCa_PRKCB_ST	P35568	IRS1	P05771	PRKCB	S303	R302L	302	Missense	proximal	-1	no	4.483	3.871	EPSD	COSMIC	0.942	Down-regulation
AGC_PKC_PKCa_PRKCB_ST	P35568	IRS1	P05771	PRKCB	S303	I308M	308	Missense	distal	5	no	4.483	4.364	EPSD	COSMIC	0.942	Down-regulation
AGC_PKC_PKCa_PRKCB_ST	P35568	IRS1	P05771	PRKCB	S303	A310V	310	Missense	distal	7	no	4.483	4.428	EPSD	COSMIC	0.942	Down-regulation
AGC_PKC_PKCa_PRKCB_ST	P35568	IRS1	P05771	PRKCB	S307	R301C	301	Missense	distal	-6	no	4.780	4.425	EPSD	COSMIC	0.942	Down-regulation
AGC_PKC_PKCa_PRKCB_ST	P35568	IRS1	P05771	PRKCB	S307	E306K	306	Missense	proximal	-1	no	4.780	4.924	EPSD	COSMIC	0.942	Up-regulation
AGC_PKC_PKCa_PRKCB_ST	P35568	IRS1	P05771	PRKCB	S307	A310T	310	Missense	distal	3	no	4.780	5.174	EPSD	COSMIC	0.942	Up-regulation
AGC_PKC_PKCa_PRKCB_ST	P35568	IRS1	P05771	PRKCB	S307	P313L	313	Missense	distal	6	no	4.780	4.079	EPSD	COSMIC;GDSC;CCLE	0.942	Down-regulation
AGC_PKC_PKCa_PRKCB_ST	P35568	IRS1	P05771	PRKCB	S307	R302L	302	Missense	distal	-5	no	4.780	4.525	EPSD	COSMIC	0.942	Down-regulation
AGC_PKC_PKCa_PRKCB_ST	P35568	IRS1	P05771	PRKCB	S307	I308M	308	Missense	proximal	1	no	4.780	3.770	EPSD	COSMIC	0.942	Down-regulation
AGC_PKC_PKCa_PRKCB_ST	P35568	IRS1	P05771	PRKCB	S307	A310V	310	Missense	distal	3	no	4.780	4.625	EPSD	COSMIC	0.942	Down-regulation
AGC_PKC_PKCa_PRKCB_ST	P35568	IRS1	P05771	PRKCB	S323	R327L	327	Missense	distal	4	no	8.318	7.012	PhosphoSitePlus;EPSD	COSMIC	0.942	Down-regulation
AGC_PKC_PKCa_PRKCB_ST	P35568	IRS1	P05771	PRKCB	S323	R325H	325	Missense	proximal	2	no	8.318	1.956	PhosphoSitePlus;EPSD	COSMIC;CCLE	0.942	Down-regulation
AGC_PKC_PKCa_PRKCB_ST	P35568	IRS1	P05771	PRKCB	S323	R327C	327	Missense	distal	4	no	8.318	7.179	PhosphoSitePlus;EPSD	COSMIC;CCLE	0.942	Down-regulation
AGC_PKC_PKCa_PRKCB_ST	P35568	IRS1	P05771	PRKCB	S323	M316V	316	Missense	distal	-7	no	8.318	8.218	PhosphoSitePlus;EPSD	COSMIC	0.942	Down-regulation
AGC_PKC_PKCa_PRKCB_ST	P35568	IRS1	P05771	PRKCB	S323	M316I	316	Missense	distal	-7	no	8.318	8.048	PhosphoSitePlus;EPSD	COSMIC	0.942	Down-regulation
AGC_PKC_PKCa_PRKCB_ST	P35568	IRS1	P05771	PRKCB	S323	R325C	325	Missense	proximal	2	no	8.318	3.825	PhosphoSitePlus;EPSD	COSMIC	0.942	Down-regulation
AGC_PKC_PKCa_PRKCB_ST	P35568	IRS1	P05771	PRKCB	S323	F324L	324	Missense	proximal	1	no	8.318	7.818	PhosphoSitePlus;EPSD	COSMIC	0.942	Down-regulation
AGC_PKC_PKCa_PRKCB_ST	P35568	IRS1	P05771	PRKCB	S330	G332R	332	Missense	proximal	2	no	-0.706	8.028	EPSD	COSMIC	0.942	Gain
AGC_PKC_PKCa_PRKCB_ST	P35568	IRS1	P05771	PRKCB	T351	A356P	356	Missense	distal	5	no	2.051	1.865	EPSD	COSMIC	0.942	Down-regulation
AGC_PKC_PKCa_PRKCB_ST	P35568	IRS1	P05771	PRKCB	T351	R358Q	358	Missense	distal	7	no	2.051	2.127	EPSD	COSMIC	0.942	Up-regulation
AGC_PKC_PKCa_PRKCB_ST	P35568	IRS1	P05771	PRKCB	T351	N352D	352	Missense	proximal	1	no	2.051	3.053	EPSD	COSMIC	0.942	Up-regulation
AGC_PKC_PKCa_PRKCB_ST	P35568	IRS1	P05771	PRKCB	T351	P349L	349	Missense	proximal	-2	no	2.051	1.363	EPSD	COSMIC	0.942	Down-regulation
AGC_PKC_PKCa_PRKCB_ST	P35568	IRS1	P05771	PRKCB	T351	P346S	346	Missense	distal	-5	no	2.051	2.077	EPSD	COSMIC	0.942	Up-regulation
AGC_PKC_PKCa_PRKCB_ST	P35568	IRS1	P05771	PRKCB	S362	L369F	369	Missense	distal	7	no	4.417	4.415	EPSD	COSMIC	0.942	Down-regulation
AGC_PKC_PKCa_PRKCB_ST	P35568	IRS1	P05771	PRKCB	S362	A356P	356	Missense	distal	-6	no	4.417	4.381	EPSD	COSMIC	0.942	Down-regulation
AGC_PKC_PKCa_PRKCB_ST	P35568	IRS1	P05771	PRKCB	S362	R364Q	364	Missense	proximal	2	no	4.417	-2.132	EPSD	COSMIC	0.942	Loss
AGC_PKC_PKCa_PRKCB_ST	P35568	IRS1	P05771	PRKCB	S362	R358Q	358	Missense	distal	-4	no	4.417	4.539	EPSD	COSMIC	0.942	Up-regulation
AGC_PKC_PKCa_PRKCB_ST	P35568	IRS1	P05771	PRKCB	S362	G361S	361	Missense	proximal	-1	no	4.417	4.346	EPSD	COSMIC	0.942	Down-regulation
AGC_PKC_PKCa_PRKCB_ST	P35568	IRS1	P05771	PRKCB	S413	S415L	415	Missense	proximal	2	no	1.222	0.587	EPSD	COSMIC	0.942	Loss
AGC_PKC_PKCa_PRKCB_ST	P35568	IRS1	P05771	PRKCB	S413	G418V	418	Missense	distal	5	no	1.222	1.238	EPSD	COSMIC;GDSC;CCLE	0.942	Up-regulation
AGC_PKC_PKCa_PRKCB_ST	P35568	IRS1	P05771	PRKCB	S441	P435L	435	Missense	distal	-6	no	7.878	7.893	EPSD;PhosphoSitePlus	COSMIC	0.942	Up-regulation
AGC_PKC_PKCa_PRKCB_ST	P35568	IRS1	P05771	PRKCB	S441	R439Q	439	Missense	proximal	-2	no	7.878	6.906	EPSD;PhosphoSitePlus	COSMIC	0.942	Down-regulation
AGC_PKC_PKCa_PRKCB_ST	P35568	IRS1	P05771	PRKCB	S441	D448E	448	Missense	distal	7	no	7.878	7.936	EPSD;PhosphoSitePlus	COSMIC	0.942	Up-regulation
AGC_PKC_PKCa_PRKCB_ST	P35568	IRS1	P05771	PRKCB	S441	S441Y	441	Missense	central	0	yes	7.878	0.000	EPSD;PhosphoSitePlus	COSMIC	0.942	Loss
AGC_PKC_PKCa_PRKCB_ST	P35568	IRS1	P05771	PRKCB	S441	S434G	434	Missense	distal	-7	no	7.878	7.959	EPSD;PhosphoSitePlus	COSMIC	0.942	Up-regulation
AGC_PKC_PKCa_PRKCB_ST	P35568	IRS1	P05771	PRKCB	S441	S441F	441	Missense	central	0	yes	7.878	0.000	EPSD;PhosphoSitePlus	COSMIC	0.942	Loss
AGC_PKC_PKCa_PRKCB_ST	P35568	IRS1	P05771	PRKCB	S441	R443C	443	Missense	proximal	2	no	7.878	3.385	EPSD;PhosphoSitePlus	COSMIC	0.942	Down-regulation
AGC_PKC_PKCa_PRKCB_ST	P35568	IRS1	P05771	PRKCB	S441	P435F	435	Missense	distal	-6	no	7.878	7.886	EPSD;PhosphoSitePlus	COSMIC	0.942	Up-regulation
AGC_PKC_PKCa_PRKCB_ST	P35568	IRS1	P05771	PRKCB	S441	P447L	447	Missense	distal	6	no	7.878	7.176	EPSD;PhosphoSitePlus	COSMIC	0.942	Down-regulation
AGC_PKC_PKCa_PRKCB_ST	P35568	IRS1	P05771	PRKCB	S441	R443L	443	Missense	proximal	2	no	7.878	1.246	EPSD;PhosphoSitePlus	COSMIC	0.942	Down-regulation
AGC_PKC_PKCa_PRKCB_ST	P35568	IRS1	P05771	PRKCB	S441	S444I	444	Missense	distal	3	no	7.878	7.670	EPSD;PhosphoSitePlus	COSMIC	0.942	Down-regulation
AGC_PKC_PKCa_PRKCB_ST	P35568	IRS1	P05771	PRKCB	S581	E584K	584	Missense	distal	3	no	1.534	1.482	EPSD	COSMIC	0.942	Down-regulation
AGC_PKC_PKCa_PRKCB_ST	P35568	IRS1	P05771	PRKCB	S581	P578S	578	Missense	distal	-3	no	1.534	1.351	EPSD	COSMIC	0.942	Down-regulation
AGC_PKC_PKCa_PRKCB_ST	P35568	IRS1	P05771	PRKCB	S581	F576L	576	Missense	distal	-5	no	1.534	1.499	EPSD	COSMIC	0.942	Down-regulation
AGC_PKC_PKCa_PRKCB_ST	P35568	IRS1	P05771	PRKCB	S603	H598R	598	Missense	distal	-5	no	2.483	2.730	EPSD	COSMIC	0.942	Up-regulation
AGC_PKC_PKCa_PRKCB_ST	P35568	IRS1	P05771	PRKCB	S603	G596E	596	Missense	distal	-7	no	2.483	2.290	EPSD	COSMIC	0.942	Down-regulation
AGC_PKC_PKCa_PRKCB_ST	P35568	IRS1	P05771	PRKCB	S603	H599Y	599	Missense	distal	-4	no	2.483	2.373	EPSD	COSMIC	0.942	Down-regulation
AGC_PKC_PKCa_PRKCB_ST	P35568	IRS1	P05771	PRKCB	S603	H599Q	599	Missense	distal	-4	no	2.483	2.298	EPSD	COSMIC	0.942	Down-regulation
AGC_PKC_PKCa_PRKCB_ST	P35568	IRS1	P05771	PRKCB	S624	G628D	628	Missense	distal	4	no	2.446	2.859	EPSD	COSMIC	0.942	Up-regulation
AGC_PKC_PKCa_PRKCB_ST	P35568	IRS1	P05771	PRKCB	S624	R626Q	626	Missense	proximal	2	no	2.446	-4.103	EPSD	COSMIC	0.942	Loss
AGC_PKC_PKCa_PRKCB_ST	P35568	IRS1	P05771	PRKCB	S624	V622M	622	Missense	proximal	-2	no	2.446	1.988	EPSD	COSMIC	0.942	Down-regulation
AGC_PKC_PKCa_PRKCB_ST	P35568	IRS1	P05771	PRKCB	S624	G630E	630	Missense	distal	6	no	2.446	3.527	EPSD	COSMIC	0.942	Up-regulation
AGC_PKC_PKCa_PRKCB_ST	P35568	IRS1	P05771	PRKCB	S636	V640I	640	Missense	distal	4	no	1.075	1.136	EPSD	COSMIC;GDSC;CCLE	0.942	Up-regulation
AGC_PKC_PKCa_PRKCB_ST	P35568	IRS1	P05771	PRKCB	S636	A642T	642	Missense	distal	6	no	1.075	1.632	EPSD	COSMIC	0.942	Up-regulation
AGC_PKC_PKCa_PRKCB_ST	P35568	IRS1	P05771	PRKCB	S636	G630E	630	Missense	distal	-6	no	1.075	1.342	EPSD	COSMIC	0.942	Up-regulation
AGC_PKC_PKCa_PRKCB_ST	P35568	IRS1	P05771	PRKCB	S795	S792F	792	Missense	distal	-3	no	3.003	3.215	EPSD	COSMIC	0.942	Up-regulation
AGC_PKC_PKCa_PRKCB_ST	P35568	IRS1	P05771	PRKCB	S795	R790C	790	Missense	distal	-5	no	3.003	2.769	EPSD	COSMIC	0.942	Down-regulation
AGC_PKC_PKCa_PRKCB_ST	P35568	IRS1	P05771	PRKCB	S795	A801V	801	Missense	distal	6	no	3.003	3.078	EPSD	COSMIC	0.942	Up-regulation
AGC_PKC_PKCa_PRKCB_ST	P35568	IRS1	P05771	PRKCB	T870	P872T	872	Missense	proximal	2	no	0.115	1.304	EPSD	COSMIC	0.942	Gain
AGC_PKC_PKCa_PRKCB_ST	P35568	IRS1	P05771	PRKCB	S995	M992K	992	Missense	distal	-3	no	-2.160	1.073	EPSD	COSMIC	0.942	Gain
AGC_PKC_PKCa_PRKCB_ST	P35568	IRS1	P05771	PRKCB	S1084	P1079S	1079	Missense	distal	-5	no	6.007	6.032	EPSD	COSMIC	0.942	Up-regulation
AGC_PKC_PKCa_PRKCB_ST	P35568	IRS1	P05771	PRKCB	S1084	S1078I	1078	Missense	distal	-6	no	6.007	5.960	EPSD	COSMIC	0.942	Down-regulation
AGC_PKC_PKCa_PRKCB_ST	P35568	IRS1	P05771	PRKCB	S1084	V1087A	1087	Missense	distal	3	no	6.007	6.162	EPSD	COSMIC	0.942	Up-regulation
AGC_PKC_PKCa_PRKCB_ST	P35568	IRS1	P05771	PRKCB	S1084	R1081C	1081	Missense	distal	-3	no	6.007	2.107	EPSD	COSMIC	0.942	Down-regulation
AGC_PKC_PKCa_PRKCB_ST	P35568	IRS1	P05771	PRKCB	S1100	E1102K	1102	Missense	proximal	2	no	-0.354	5.060	EPSD	COSMIC	0.942	Gain
AGC_PKC_PKCa_PRKCB_ST	P35568	IRS1	P05771	PRKCB	S1101	R1097W	1097	Missense	distal	-4	no	1.721	2.299	EPSD	COSMIC	0.942	Up-regulation
AGC_PKC_PKCa_PRKCB_ST	P35568	IRS1	P05771	PRKCB	S1101	E1102K	1102	Missense	proximal	1	no	1.721	3.712	EPSD	COSMIC	0.942	Up-regulation
AGC_PKC_PKCa_PRKCB_ST	P35568	IRS1	P05771	PRKCB	S1142	R1140C	1140	Missense	proximal	-2	no	4.666	3.200	EPSD	COSMIC;CCLE	0.942	Down-regulation
AGC_PKC_PKCa_PRKCB_ST	P35568	IRS1	P05771	PRKCB	S1143	R1140C	1140	Missense	distal	-3	no	1.236	-2.664	EPSD	COSMIC;CCLE	0.942	Loss
AGC_PKC_PKCa_PRKCB_ST	P35568	IRS1	P05771	PRKCB	S1218	G1212V	1212	Missense	distal	-6	no	2.552	2.680	EPSD	COSMIC	0.942	Up-regulation
AGC_PKC_PKCa_PRKCB_ST	P35568	IRS1	P05771	PRKCB	S1218	R1220C	1220	Missense	proximal	2	no	2.552	-1.941	EPSD	COSMIC	0.942	Loss
AGC_PKC_PKCa_PRKCB_ST	P35568	IRS1	P05771	PRKCB	S1218	D1225Y	1225	Missense	distal	7	no	2.552	2.592	EPSD	COSMIC	0.942	Up-regulation
AGC_PKC_PKCa_PRKCB_ST	P35568	IRS1	P05771	PRKCB	S1218	E1224Q	1224	Missense	distal	6	no	2.552	2.092	EPSD	COSMIC	0.942	Down-regulation
AGC_PKC_PKCa_PRKCB_ST	P35568	IRS1	P05771	PRKCB	T1219	G1212V	1212	Missense	distal	-7	no	3.984	3.909	EPSD	COSMIC	0.942	Down-regulation
AGC_PKC_PKCa_PRKCB_ST	P35568	IRS1	P05771	PRKCB	T1219	R1220C	1220	Missense	proximal	1	no	3.984	1.347	EPSD	COSMIC	0.942	Down-regulation
AGC_PKC_PKCa_PRKCB_ST	P35568	IRS1	P05771	PRKCB	T1219	D1225Y	1225	Missense	distal	6	no	3.984	3.655	EPSD	COSMIC	0.942	Down-regulation
AGC_PKC_PKCa_PRKCB_ST	P35568	IRS1	P05771	PRKCB	T1219	E1224Q	1224	Missense	distal	5	no	3.984	4.115	EPSD	COSMIC	0.942	Up-regulation
AGC_PKC_PKCa_PRKCB_ST	P35568	IRS1	P05771	PRKCB	T1219	L1226V	1226	Missense	distal	7	no	3.984	3.986	EPSD	COSMIC	0.942	Up-regulation
AGC_PKC_PKCa_PRKCB_ST	P35568	IRS1	P05771	PRKCB	S1223	E1224Q	1224	Missense	proximal	1	no	0.713	1.892	EPSD	COSMIC	0.942	Gain
AGC_PKC_PKCa_PRKCB_ST	Q13131	PRKAA1	P05771	PRKCB	S197	I196M	196	Missense	proximal	-1	no	2.883	3.051	EPSD	COSMIC	0.942	Up-regulation
AGC_PKC_PKCa_PRKCB_ST	Q13131	PRKAA1	P05771	PRKCB	T382	P376S	376	Missense	distal	-6	no	3.070	3.184	EPSD	COSMIC	0.942	Up-regulation
AGC_PKC_PKCa_PRKCB_ST	Q13131	PRKAA1	P05771	PRKCB	S496	V497A	497	Missense	proximal	1	no	1.295	0.919	PhosphoSitePlus	COSMIC	0.942	Loss
AGC_PKC_PKCa_PRKCB_ST	Q13131	PRKAA1	P05771	PRKCB	S496	R501G	501	Missense	distal	5	no	1.295	0.866	PhosphoSitePlus	COSMIC	0.942	Loss
AGC_PKC_PKCa_PRKCB_ST	P11171	EPB41	P05771	PRKCB	S180	E183Q	183	Missense	distal	3	no	1.126	0.966	EPSD	COSMIC	0.942	Down-regulation
AGC_PKC_PKCa_PRKCB_ST	P11171	EPB41	P05771	PRKCB	S180	E177K	177	Missense	distal	-3	no	1.126	4.461	EPSD	COSMIC	0.942	Up-regulation
AGC_PKC_PKCa_PRKCB_ST	P11171	EPB41	P05771	PRKCB	S188	E183Q	183	Missense	distal	-5	no	1.715	1.809	EPSD	COSMIC	0.942	Up-regulation
AGC_PKC_PKCa_PRKCB_ST	P11171	EPB41	P05771	PRKCB	S200	Q201E	201	Missense	proximal	1	no	4.920	3.740	EPSD	COSMIC	0.942	Down-regulation
AGC_PKC_PKCa_PRKCB_ST	P11171	EPB41	P05771	PRKCB	S200	P203Q	203	Missense	distal	3	no	4.920	5.055	EPSD	COSMIC	0.942	Up-regulation
AGC_PKC_PKCa_PRKCB_ST	P11171	EPB41	P05771	PRKCB	S200	R205C	205	Missense	distal	5	no	4.920	4.477	EPSD	COSMIC	0.942	Down-regulation
AGC_PKC_PKCa_PRKCB_ST	P11171	EPB41	P05771	PRKCB	S441	V437M	437	Missense	distal	-4	no	2.927	3.003	EPSD	COSMIC	0.942	Up-regulation
AGC_PKC_PKCa_PRKCB_ST	P11171	EPB41	P05771	PRKCB	S441	K439N	439	Missense	proximal	-2	no	2.927	1.096	EPSD	COSMIC	0.942	Down-regulation
AGC_PKC_PKCa_PRKCB_ST	P11171	EPB41	P05771	PRKCB	S441	R444S	444	Missense	distal	3	no	2.927	2.162	EPSD	COSMIC	0.942	Down-regulation
AGC_PKC_PKCa_PRKCB_ST	P11171	EPB41	P05771	PRKCB	S441	R444H	444	Missense	distal	3	no	2.927	2.122	EPSD	COSMIC	0.942	Down-regulation
AGC_PKC_PKCa_PRKCB_ST	P11171	EPB41	P05771	PRKCB	S446	K439N	439	Missense	distal	-7	no	4.381	4.683	EPSD	COSMIC	0.942	Up-regulation
AGC_PKC_PKCa_PRKCB_ST	P11171	EPB41	P05771	PRKCB	S446	R444S	444	Missense	proximal	-2	no	4.381	2.428	EPSD	COSMIC	0.942	Down-regulation
AGC_PKC_PKCa_PRKCB_ST	P11171	EPB41	P05771	PRKCB	S446	R452Q	452	Missense	distal	6	no	4.381	3.575	EPSD	COSMIC	0.942	Down-regulation
AGC_PKC_PKCa_PRKCB_ST	P11171	EPB41	P05771	PRKCB	S446	R444H	444	Missense	proximal	-2	no	4.381	2.365	EPSD	COSMIC	0.942	Down-regulation
AGC_PKC_PKCa_PRKCB_ST	P11171	EPB41	P05771	PRKCB	S469	I463N	463	Missense	distal	-6	no	6.823	6.967	EPSD	COSMIC	0.942	Up-regulation
AGC_PKC_PKCa_PRKCB_ST	P11171	EPB41	P05771	PRKCB	S469	K466E	466	Missense	distal	-3	no	6.823	3.488	EPSD	COSMIC	0.942	Down-regulation
AGC_PKC_PKCa_PRKCB_ST	P11171	EPB41	P05771	PRKCB	S521	I524V	524	Missense	distal	3	no	1.966	1.804	EPSD	COSMIC	0.942	Down-regulation
AGC_PKC_PKCa_PRKCB_ST	P11171	EPB41	P05771	PRKCB	S521	L523V	523	Missense	proximal	2	no	1.966	3.295	EPSD	COSMIC	0.942	Up-regulation
AGC_PKC_PKCa_PRKCB_ST	P11171	EPB41	P05771	PRKCB	S536	A535G	535	Missense	proximal	-1	no	9.014	9.057	EPSD	COSMIC	0.942	Up-regulation
AGC_PKC_PKCa_PRKCB_ST	P11171	EPB41	P05771	PRKCB	S536	H530Y	530	Missense	distal	-6	no	9.014	9.065	EPSD	COSMIC;CCLE	0.942	Up-regulation
AGC_PKC_PKCa_PRKCB_ST	P11171	EPB41	P05771	PRKCB	S536	S542R	542	Missense	distal	6	no	9.014	9.983	EPSD	COSMIC	0.942	Up-regulation
AGC_PKC_PKCa_PRKCB_ST	P11171	EPB41	P05771	PRKCB	S536	A535T	535	Missense	proximal	-1	no	9.014	9.169	EPSD	COSMIC	0.942	Up-regulation
AGC_PKC_PKCa_PRKCB_ST	P11171	EPB41	P05771	PRKCB	S540	A535G	535	Missense	distal	-5	no	3.582	3.534	EPSD	COSMIC	0.942	Down-regulation
AGC_PKC_PKCa_PRKCB_ST	P11171	EPB41	P05771	PRKCB	S540	S542R	542	Missense	proximal	2	no	3.582	9.579	EPSD	COSMIC	0.942	Up-regulation
AGC_PKC_PKCa_PRKCB_ST	P11171	EPB41	P05771	PRKCB	S540	A535T	535	Missense	distal	-5	no	3.582	3.591	EPSD	COSMIC	0.942	Up-regulation
AGC_PKC_PKCa_PRKCB_ST	P11171	EPB41	P05771	PRKCB	S555	D553G	553	Missense	proximal	-2	no	2.845	3.224	EPSD	COSMIC;CCLE	0.942	Up-regulation
AGC_PKC_PKCa_PRKCB_ST	P11171	EPB41	P05771	PRKCB	S555	P558L	558	Missense	distal	3	no	2.845	2.458	EPSD	COSMIC	0.942	Down-regulation
AGC_PKC_PKCa_PRKCB_ST	P11171	EPB41	P05771	PRKCB	S560	D553G	553	Missense	distal	-7	no	1.167	1.437	EPSD	COSMIC;CCLE	0.942	Up-regulation
AGC_PKC_PKCa_PRKCB_ST	P11171	EPB41	P05771	PRKCB	S560	P558L	558	Missense	proximal	-2	no	1.167	0.479	EPSD	COSMIC	0.942	Loss
AGC_PKC_PKCa_PRKCB_ST	P11171	EPB41	P05771	PRKCB	S560	G567D	567	Missense	distal	7	no	1.167	0.940	EPSD	COSMIC	0.942	Loss
AGC_PKC_PKCa_PRKCB_ST	P11171	EPB41	P05771	PRKCB	S560	G567S	567	Missense	distal	7	no	1.167	1.037	EPSD	COSMIC	0.942	Down-regulation
AGC_PKC_PKCa_PRKCB_ST	P11171	EPB41	P05771	PRKCB	S560	G567C	567	Missense	distal	7	no	1.167	1.064	EPSD	COSMIC	0.942	Down-regulation
AGC_PKC_PKCa_PRKCB_ST	P11171	EPB41	P05771	PRKCB	S709	W704S	704	Missense	distal	-5	no	3.383	3.513	EPSD	COSMIC	0.942	Up-regulation
AGC_PKC_PKCa_PRKCB_ST	P11171	EPB41	P05771	PRKCB	S709	R707S	707	Missense	proximal	-2	no	3.383	1.430	EPSD	COSMIC	0.942	Down-regulation
AGC_PKC_PKCa_PRKCB_ST	P11171	EPB41	P05771	PRKCB	T736	D741Y	741	Missense	distal	5	no	1.884	1.760	EPSD	COSMIC	0.942	Down-regulation
AGC_PKC_PKCa_PRKCB_ST	P11171	EPB41	P05771	PRKCB	T736	T734I	734	Missense	proximal	-2	no	1.884	1.721	EPSD	COSMIC	0.942	Down-regulation
AGC_PKC_PKCa_PRKCB_ST	P16949	STMN1	P05771	PRKCB	S16	R14C	14	Missense	proximal	-2	no	1.083	-0.383	EPSD	COSMIC	0.942	Loss
AGC_PKC_PKCa_PRKCB_ST	P16949	STMN1	P05771	PRKCB	S16	Q18E	18	Missense	proximal	2	no	1.083	0.594	EPSD	COSMIC	0.942	Loss
AGC_PKC_PKCa_PRKCB_ST	P16949	STMN1	P05771	PRKCB	S25	Q18E	18	Missense	distal	-7	no	1.193	1.328	PhosphoSitePlus;EPSD	COSMIC	0.942	Up-regulation
AGC_PKC_PKCa_PRKCB_ST	P16949	STMN1	P05771	PRKCB	S63	R61S	61	Missense	proximal	-2	no	0.957	-0.996	EPSD	COSMIC	0.942	Loss
AGC_PKC_PKCa_PRKCB_ST	P14679	TYR	P05771	PRKCB	S339	D333N	333	Missense	distal	-6	no	6.771	6.837	EPSD	COSMIC	0.942	Up-regulation
AGC_PKC_PKCa_PRKCB_ST	P14679	TYR	P05771	PRKCB	S339	L344V	344	Missense	distal	5	no	6.771	6.815	EPSD	COSMIC	0.942	Up-regulation
AGC_PKC_PKCa_PRKCB_ST	P14679	TYR	P05771	PRKCB	S339	M332I	332	Missense	distal	-7	no	6.771	6.501	EPSD	COSMIC	0.942	Down-regulation
AGC_PKC_PKCa_PRKCB_ST	P14679	TYR	P05771	PRKCB	S339	T343P	343	Missense	distal	4	no	6.771	6.934	EPSD	COSMIC	0.942	Up-regulation
AGC_PKC_PKCa_PRKCB_ST	P14679	TYR	P05771	PRKCB	S339	G346V	346	Missense	distal	7	no	6.771	6.703	EPSD	COSMIC	0.942	Down-regulation
AGC_PKC_PKCa_PRKCB_ST	P28329	CHAT	P05771	PRKCB	S244	L248V	248	Missense	distal	4	no	1.015	1.384	EPSD	COSMIC	0.942	Up-regulation
AGC_PKC_PKCa_PRKCB_ST	P28329	CHAT	P05771	PRKCB	S244	L248P	248	Missense	distal	4	no	1.015	1.438	EPSD	COSMIC	0.942	Up-regulation
AGC_PKC_PKCa_PRKCB_ST	P28329	CHAT	P05771	PRKCB	S244	S240F	240	Missense	distal	-4	no	1.015	0.994	EPSD	COSMIC	0.942	Down-regulation
AGC_PKC_PKCa_PRKCB_ST	P28329	CHAT	P05771	PRKCB	S244	L243F	243	Missense	proximal	-1	no	1.015	1.173	EPSD	COSMIC	0.942	Up-regulation
AGC_PKC_PKCa_PRKCB_ST	P28329	CHAT	P05771	PRKCB	S244	D250N	250	Missense	distal	6	no	1.015	1.282	EPSD	COSMIC	0.942	Up-regulation
AGC_PKC_PKCa_PRKCB_ST	P28329	CHAT	P05771	PRKCB	S244	S237N	237	Missense	distal	-7	no	1.015	1.002	EPSD	COSMIC	0.942	Down-regulation
AGC_PKC_PKCa_PRKCB_ST	P28329	CHAT	P05771	PRKCB	T373	R375Q	375	Missense	proximal	2	no	4.094	-2.455	EPSD	COSMIC	0.942	Loss
AGC_PKC_PKCa_PRKCB_ST	P28329	CHAT	P05771	PRKCB	T373	K370R	370	Missense	distal	-3	no	4.094	3.863	EPSD	COSMIC	0.942	Down-regulation
AGC_PKC_PKCa_PRKCB_ST	P28329	CHAT	P05771	PRKCB	T373	T366M	366	Missense	distal	-7	no	4.094	4.260	EPSD	COSMIC	0.942	Up-regulation
AGC_PKC_PKCa_PRKCB_ST	P28329	CHAT	P05771	PRKCB	T373	V369M	369	Missense	distal	-4	no	4.094	4.170	EPSD	COSMIC	0.942	Up-regulation
AGC_PKC_PKCa_PRKCB_ST	P28329	CHAT	P05771	PRKCB	T373	D376G	376	Missense	distal	3	no	4.094	3.725	EPSD	COSMIC	0.942	Down-regulation
AGC_PKC_PKCa_PRKCB_ST	P28329	CHAT	P05771	PRKCB	S377	R375Q	375	Missense	proximal	-2	no	1.429	0.457	EPSD	COSMIC	0.942	Loss
AGC_PKC_PKCa_PRKCB_ST	P28329	CHAT	P05771	PRKCB	S377	R383S	383	Missense	distal	6	no	1.429	0.460	EPSD	COSMIC	0.942	Loss
AGC_PKC_PKCa_PRKCB_ST	P28329	CHAT	P05771	PRKCB	S377	K370R	370	Missense	distal	-7	no	1.429	1.474	EPSD	COSMIC	0.942	Up-regulation
AGC_PKC_PKCa_PRKCB_ST	P28329	CHAT	P05771	PRKCB	S377	R383C	383	Missense	distal	6	no	1.429	0.235	EPSD	COSMIC	0.942	Loss
AGC_PKC_PKCa_PRKCB_ST	P28329	CHAT	P05771	PRKCB	S377	D376G	376	Missense	proximal	-1	no	1.429	1.303	EPSD	COSMIC	0.942	Down-regulation
AGC_PKC_PKCa_PRKCB_ST	P28329	CHAT	P05771	PRKCB	S377	R383H	383	Missense	distal	6	no	1.429	0.669	EPSD	COSMIC	0.942	Loss
AGC_PKC_PKCa_PRKCB_ST	P28329	CHAT	P05771	PRKCB	T462	R466Q	466	Missense	distal	4	no	1.163	0.543	EPSD	COSMIC	0.942	Loss
AGC_PKC_PKCa_PRKCB_ST	P28329	CHAT	P05771	PRKCB	T462	R466L	466	Missense	distal	4	no	1.163	-0.143	EPSD	COSMIC	0.942	Loss
AGC_PKC_PKCa_PRKCB_ST	P28329	CHAT	P05771	PRKCB	T462	E455D	455	Missense	distal	-7	no	1.163	1.085	EPSD	COSMIC	0.942	Down-regulation
AGC_PKC_PKCa_PRKCB_ST	P28329	CHAT	P05771	PRKCB	S464	R466Q	466	Missense	proximal	2	no	5.753	-0.796	EPSD	COSMIC	0.942	Loss
AGC_PKC_PKCa_PRKCB_ST	P28329	CHAT	P05771	PRKCB	S464	R466L	466	Missense	proximal	2	no	5.753	-0.879	EPSD	COSMIC	0.942	Loss
AGC_PKC_PKCa_PRKCB_ST	P28329	CHAT	P05771	PRKCB	S465	R466Q	466	Missense	proximal	1	no	4.475	3.777	EPSD	COSMIC	0.942	Down-regulation
AGC_PKC_PKCa_PRKCB_ST	P28329	CHAT	P05771	PRKCB	S465	R466L	466	Missense	proximal	1	no	4.475	3.791	EPSD	COSMIC	0.942	Down-regulation
AGC_PKC_PKCa_PRKCB_ST	P28329	CHAT	P05771	PRKCB	S558	E555K	555	Missense	distal	-3	no	6.129	9.464	EPSD	COSMIC	0.942	Up-regulation
AGC_PKC_PKCa_PRKCB_ST	P28329	CHAT	P05771	PRKCB	S558	A557T	557	Missense	proximal	-1	no	6.129	6.283	EPSD	COSMIC;GDSC	0.942	Up-regulation
AGC_PKC_PKCa_PRKCB_ST	P28329	CHAT	P05771	PRKCB	S558	R560C	560	Missense	proximal	2	no	6.129	1.635	EPSD	COSMIC	0.942	Down-regulation
AGC_PKC_PKCa_PRKCB_ST	P28329	CHAT	P05771	PRKCB	S558	V551A	551	Missense	distal	-7	no	6.129	6.092	EPSD	COSMIC	0.942	Down-regulation
AGC_PKC_PKCa_PRKCB_ST	P28329	CHAT	P05771	PRKCB	S594	K588M	588	Missense	distal	-6	no	2.132	1.818	EPSD	COSMIC	0.942	Down-regulation
AGC_PKC_PKCa_PRKCB_ST	P28329	CHAT	P05771	PRKCB	S594	L599F	599	Missense	distal	5	no	2.132	2.138	EPSD	COSMIC	0.942	Up-regulation
AGC_PKC_PKCa_PRKCB_ST	P28329	CHAT	P05771	PRKCB	S594	E595K	595	Missense	proximal	1	no	2.132	4.124	EPSD	COSMIC	0.942	Up-regulation
AGC_PKC_PKCa_PRKCB_ST	Q12906	ILF3	P05771	PRKCB	S19	S20F	20	Missense	proximal	1	no	1.596	3.435	EPSD	COSMIC	0.942	Up-regulation
AGC_PKC_PKCa_PRKCB_ST	Q12906	ILF3	P05771	PRKCB	S20	S20F	20	Missense	central	0	yes	2.945	0.000	EPSD	COSMIC	0.942	Loss
AGC_PKC_PKCa_PRKCB_ST	Q12906	ILF3	P05771	PRKCB	S209	A206T	206	Missense	distal	-3	no	0.500	1.947	EPSD	COSMIC	0.942	Gain
AGC_PKC_PKCa_PRKCB_ST	Q12906	ILF3	P05771	PRKCB	S647	R644Q	644	Missense	distal	-3	no	10.233	7.035	PhosphoSitePlus	COSMIC	0.942	Down-regulation
AGC_PKC_PKCa_PRKCB_ST	Q12906	ILF3	P05771	PRKCB	S647	R653W	653	Missense	distal	6	no	10.233	8.579	PhosphoSitePlus	COSMIC;GDSC	0.942	Down-regulation
AGC_PKC_PKCa_PRKCB_ST	Q12906	ILF3	P05771	PRKCB	S647	R642Q	642	Missense	distal	-5	no	10.233	10.216	PhosphoSitePlus	COSMIC	0.942	Down-regulation
AGC_PKC_PKCa_PRKCB_ST	Q12906	ILF3	P05771	PRKCB	S647	R649W	649	Missense	proximal	2	no	10.233	0.720	PhosphoSitePlus	COSMIC;CCLE	0.942	Loss
AGC_PKC_PKCa_PRKCB_ST	Q12906	ILF3	P05771	PRKCB	S854	G851R	851	Missense	distal	-3	no	-2.019	2.196	EPSD	COSMIC	0.942	Gain
AGC_PKC_PKCa_PRKCB_ST	P30273	FCER1G	P05771	PRKCB	S69	G63D	63	Missense	distal	-6	no	6.023	6.193	PhosphoSitePlus	COSMIC	0.942	Up-regulation
AGC_PKC_PKCa_PRKCB_ST	P30273	FCER1G	P05771	PRKCB	S69	Y76C	76	Missense	distal	7	no	6.023	6.106	PhosphoSitePlus	COSMIC	0.942	Up-regulation
AGC_PKC_PKCa_PRKCB_ST	P49840	GSK3A	P05771	PRKCB	S266	Q269R	269	Missense	distal	3	no	2.948	3.512	EPSD	COSMIC	0.942	Up-regulation
AGC_PKC_PKCa_PRKCB_ST	P49840	GSK3A	P05771	PRKCB	S266	G265V	265	Missense	proximal	-1	no	2.948	3.010	EPSD	COSMIC	0.942	Up-regulation
CAMK_CAMKL_PASK_PASK_ST	Q96RG2	PASK	Q96RG2	PASK	S17	P23L	23	Missense	distal	6	no	2.030	2.056	EPSD	COSMIC	1.643	Up-regulation
CAMK_CAMKL_PASK_PASK_ST	Q96RG2	PASK	Q96RG2	PASK	S17	E11K	11	Missense	distal	-6	no	2.030	2.003	EPSD	COSMIC;CCLE	1.643	Down-regulation
CAMK_CAMKL_PASK_PASK_ST	Q96RG2	PASK	Q96RG2	PASK	S104	S106P	106	Missense	proximal	2	no	1.476	1.715	EPSD	COSMIC	1.643	Gain
CAMK_CAMKL_PASK_PASK_ST	Q96RG2	PASK	Q96RG2	PASK	T850	V847A	847	Missense	distal	-3	no	2.078	2.064	EPSD	COSMIC	1.643	Down-regulation
CAMK_CAMKL_PASK_PASK_ST	Q96RG2	PASK	Q96RG2	PASK	T850	D857N	857	Missense	distal	7	no	2.078	2.090	EPSD	COSMIC	1.643	Up-regulation
CAMK_CAMKL_PASK_PASK_ST	Q96RG2	PASK	Q96RG2	PASK	T1001	Y999H	999	Missense	proximal	-2	no	1.994	1.675	EPSD	COSMIC	1.643	Down-regulation
CAMK_CAMKL_PASK_PASK_ST	Q96RG2	PASK	Q96RG2	PASK	T1001	P1004Q	1004	Missense	distal	3	no	1.994	1.564	EPSD	COSMIC	1.643	Loss
CAMK_CAMKL_PASK_PASK_ST	Q96RG2	PASK	Q96RG2	PASK	T1161	I1166F	1166	Missense	distal	5	no	4.170	4.127	EPSD;PhosphoSitePlus	COSMIC	1.643	Down-regulation
CAMK_CAMKL_PASK_PASK_ST	Q96RG2	PASK	Q96RG2	PASK	T1165	A1170T	1170	Missense	distal	5	no	4.135	4.072	PhosphoSitePlus;EPSD	COSMIC	1.643	Down-regulation
CAMK_CAMKL_PASK_PASK_ST	Q96RG2	PASK	Q96RG2	PASK	T1165	P1171L	1171	Missense	distal	6	no	4.135	4.161	PhosphoSitePlus;EPSD	COSMIC	1.643	Up-regulation
CAMK_CAMKL_PASK_PASK_ST	Q96RG2	PASK	Q96RG2	PASK	T1165	I1166F	1166	Missense	proximal	1	no	4.135	3.959	PhosphoSitePlus;EPSD	COSMIC	1.643	Down-regulation
CAMK_CAMKL_PASK_PASK_ST	P68104	EEF1A1	Q96RG2	PASK	T432	R430K	430	Missense	proximal	-2	no	4.305	3.920	PhosphoSitePlus	COSMIC	1.643	Down-regulation
CAMK_CAMKL_PASK_PASK_ST	P68104	EEF1A1	Q96RG2	PASK	T432	V433L	433	Missense	proximal	1	no	4.305	4.044	PhosphoSitePlus	COSMIC	1.643	Down-regulation
Other_TOPK_PBK_ST	P05412	JUN	Q96KB5	PBK	S63	K56N	56	Missense	distal	-7	no	6.536	6.541	EPSD;PhosphoSitePlus	COSMIC	2.342	Up-regulation
Other_TOPK_PBK_ST	P05412	JUN	Q96KB5	PBK	S73	R78H	78	Missense	distal	5	no	5.452	5.461	PhosphoSitePlus;EPSD	COSMIC	2.342	Up-regulation
Other_TOPK_PBK_ST	P05412	JUN	Q96KB5	PBK	T297	E293K	293	Missense	distal	-4	no	2.493	2.707	EPSD	COSMIC	2.342	Up-regulation
Other_TOPK_PBK_ST	P05412	JUN	Q96KB5	PBK	T297	E293Q	293	Missense	distal	-4	no	2.493	2.526	EPSD	COSMIC	2.342	Up-regulation
Other_TOPK_PBK_ST	P05412	JUN	Q96KB5	PBK	T297	T297M	297	Missense	central	0	yes	2.493	0.000	EPSD	COSMIC	2.342	Loss
Other_TOPK_PBK_ST	P05412	JUN	Q96KB5	PBK	T297	M300I	300	Missense	distal	3	no	2.493	2.491	EPSD	COSMIC	2.342	Down-regulation
Other_TOPK_PBK_ST	P81274	GPSM2	Q96KB5	PBK	S567	R563S	563	Missense	distal	-4	no	2.571	2.885	EPSD	COSMIC;GDSC;CCLE	2.342	Up-regulation
Other_TOPK_PBK_ST	Q06830	PRDX1	Q96KB5	PBK	S32	I29T	29	Missense	distal	-3	no	5.543	5.434	PhosphoSitePlus	COSMIC	2.342	Down-regulation
Other_TOPK_PBK_ST	Q06830	PRDX1	Q96KB5	PBK	S32	Y34N	34	Missense	proximal	2	no	5.543	5.505	PhosphoSitePlus	COSMIC;GDSC;CCLE	2.342	Down-regulation
Other_TOPK_PBK_ST	Q06830	PRDX1	Q96KB5	PBK	S106	P103S	103	Missense	distal	-3	no	2.591	2.800	EPSD	COSMIC	2.342	Up-regulation
Other_TOPK_PBK_ST	Q06830	PRDX1	Q96KB5	PBK	S106	D107E	107	Missense	proximal	1	no	2.591	2.613	EPSD	COSMIC	2.342	Up-regulation
Other_TOPK_PBK_ST	Q06830	PRDX1	Q96KB5	PBK	S106	P108L	108	Missense	proximal	2	no	2.591	2.681	EPSD	COSMIC	2.342	Up-regulation
Other_TOPK_PBK_ST	Q06830	PRDX1	Q96KB5	PBK	S152	L159P	159	Missense	distal	7	no	2.860	2.906	EPSD	COSMIC	2.342	Up-regulation
Other_TOPK_PBK_ST	Q06830	PRDX1	Q96KB5	PBK	S152	R151C	151	Missense	proximal	-1	no	2.860	2.805	EPSD	COSMIC	2.342	Down-regulation
Other_TOPK_PBK_ST	Q06830	PRDX1	Q96KB5	PBK	S152	R151H	151	Missense	proximal	-1	no	2.860	2.766	EPSD	COSMIC	2.342	Down-regulation
Other_PEK_PEK_EIF2AK3_ST	P05198	EIF2S1	Q9NZJ5	EIF2AK3	S49	L48V	48	Missense	proximal	-1	no	4.319	4.260	PhosphoSitePlus;EPSD	COSMIC	0.763	Down-regulation
Other_PEK_PEK_EIF2AK3_ST	P05198	EIF2S1	Q9NZJ5	EIF2AK3	S49	R55H	55	Missense	distal	6	no	4.319	4.379	PhosphoSitePlus;EPSD	COSMIC	0.763	Up-regulation
Other_PEK_PEK_EIF2AK3_ST	P05198	EIF2S1	Q9NZJ5	EIF2AK3	S49	R55C	55	Missense	distal	6	no	4.319	4.366	PhosphoSitePlus;EPSD	COSMIC	0.763	Up-regulation
Other_PEK_PEK_EIF2AK3_ST	P05198	EIF2S1	Q9NZJ5	EIF2AK3	S52	L48V	48	Missense	distal	-4	no	3.905	3.885	EPSD;PhosphoSitePlus	COSMIC	0.763	Down-regulation
Other_PEK_PEK_EIF2AK3_ST	P05198	EIF2S1	Q9NZJ5	EIF2AK3	S52	R55H	55	Missense	distal	3	no	3.905	3.874	EPSD;PhosphoSitePlus	COSMIC	0.763	Down-regulation
Other_PEK_PEK_EIF2AK3_ST	P05198	EIF2S1	Q9NZJ5	EIF2AK3	S52	R55C	55	Missense	distal	3	no	3.905	3.880	EPSD;PhosphoSitePlus	COSMIC	0.763	Down-regulation
TKL_RAF_RAF_BRAF_ST	P19634	SLC9A1	P15056	BRAF	T653	D657Y	657	Missense	distal	4	no	4.142	4.122	PhosphoSitePlus	COSMIC	2.269	Down-regulation
TKL_RAF_RAF_BRAF_ST	Q92934	BAD	P15056	BRAF	S75	A78E	78	Missense	distal	3	no	4.371	4.233	PhosphoSitePlus;EPSD	COSMIC	2.269	Down-regulation
TKL_RAF_RAF_BRAF_ST	Q92934	BAD	P15056	BRAF	T80	A78E	78	Missense	proximal	-2	no	2.363	2.118	EPSD	COSMIC	2.269	Loss
TKL_RAF_RAF_BRAF_ST	Q92934	BAD	P15056	BRAF	T80	D83Y	83	Missense	distal	3	no	2.363	2.333	EPSD	COSMIC	2.269	Down-regulation
TKL_RAF_RAF_BRAF_ST	Q92934	BAD	P15056	BRAF	S99	P102L	102	Missense	distal	3	no	4.087	4.059	EPSD;PhosphoSitePlus	COSMIC	2.269	Down-regulation
TKL_RAF_RAF_BRAF_ST	Q92934	BAD	P15056	BRAF	S99	S97P	97	Missense	proximal	-2	no	4.087	4.338	EPSD;PhosphoSitePlus	COSMIC	2.269	Up-regulation
TKL_RAF_RAF_BRAF_ST	Q92934	BAD	P15056	BRAF	S99	R98H	98	Missense	proximal	-1	no	4.087	3.993	EPSD;PhosphoSitePlus	COSMIC	2.269	Down-regulation
TKL_RAF_RAF_BRAF_ST	Q92934	BAD	P15056	BRAF	S99	P101S	101	Missense	proximal	2	no	4.087	4.094	EPSD;PhosphoSitePlus	COSMIC	2.269	Up-regulation
TKL_RAF_RAF_BRAF_ST	Q92934	BAD	P15056	BRAF	S118	S124F	124	Missense	distal	6	no	4.381	4.446	EPSD;PhosphoSitePlus	COSMIC	2.269	Up-regulation
TKL_RAF_RAF_BRAF_ST	Q92934	BAD	P15056	BRAF	S134	K127N	127	Missense	distal	-7	no	4.161	4.208	EPSD;PhosphoSitePlus	COSMIC	2.269	Up-regulation
TKL_RAF_RAF_BRAF_ST	Q92934	BAD	P15056	BRAF	S134	K133N	133	Missense	proximal	-1	no	4.161	4.279	EPSD;PhosphoSitePlus	COSMIC	2.269	Up-regulation
TKL_RAF_RAF_BRAF_ST	Q92934	BAD	P15056	BRAF	S145	W147R	147	Missense	proximal	2	no	2.564	2.501	EPSD	COSMIC	2.269	Down-regulation
TKL_RAF_RAF_BRAF_ST	P68104	EEF1A1	P15056	BRAF	S21	G25C	25	Missense	distal	4	no	4.317	4.254	EPSD;PhosphoSitePlus	COSMIC	2.269	Down-regulation
TKL_RAF_RAF_BRAF_ST	P68104	EEF1A1	P15056	BRAF	S21	H26R	26	Missense	distal	5	no	4.317	4.083	EPSD;PhosphoSitePlus	COSMIC	2.269	Down-regulation
TKL_RAF_RAF_BRAF_ST	P68104	EEF1A1	P15056	BRAF	T88	H95L	95	Missense	distal	7	no	3.164	3.188	PhosphoSitePlus;EPSD	COSMIC	2.269	Up-regulation
TKL_RAF_RAF_BRAF_ST	P68104	EEF1A1	P15056	BRAF	S224	A223V	223	Missense	proximal	-1	no	2.255	2.289	EPSD	COSMIC	2.269	Gain
TKL_RAF_RAF_BRAF_ST	Q9H9S0	NANOG	P15056	BRAF	S57	V51F	51	Missense	distal	-6	no	2.653	2.877	EPSD	COSMIC	2.269	Up-regulation
TKL_RAF_RAF_BRAF_ST	Q9H9S0	NANOG	P15056	BRAF	S57	L54V	54	Missense	distal	-3	no	2.653	2.674	EPSD	COSMIC	2.269	Up-regulation
TKL_RAF_RAF_BRAF_ST	Q9H9S0	NANOG	P15056	BRAF	S57	S52T	52	Missense	distal	-5	no	2.653	2.590	EPSD	COSMIC;CCLE	2.269	Down-regulation
TKL_RAF_RAF_BRAF_ST	P15056	BRAF	P15056	BRAF	T244	F247L	247	Missense	distal	3	no	2.425	2.374	EPSD	COSMIC	2.269	Down-regulation
TKL_RAF_RAF_BRAF_ST	P15056	BRAF	P15056	BRAF	T244	V238I	238	Missense	distal	-6	no	2.425	2.627	EPSD	COSMIC	2.269	Up-regulation
TKL_RAF_RAF_BRAF_ST	P15056	BRAF	P15056	BRAF	T244	F243S	243	Missense	proximal	-1	no	2.425	2.609	EPSD	COSMIC	2.269	Up-regulation
TKL_RAF_RAF_BRAF_ST	P15056	BRAF	P15056	BRAF	S335	L331F	331	Missense	distal	-4	no	2.230	2.334	EPSD	COSMIC	2.269	Gain
TKL_RAF_RAF_BRAF_ST	P15056	BRAF	P15056	BRAF	S335	P334S	334	Missense	proximal	-1	no	2.230	2.414	EPSD	COSMIC	2.269	Gain
TKL_RAF_RAF_BRAF_ST	P15056	BRAF	P15056	BRAF	T373	E375D	375	Missense	proximal	2	no	3.959	3.945	EPSD;PhosphoSitePlus	COSMIC;GDSC;CCLE	2.269	Down-regulation
TKL_RAF_RAF_BRAF_ST	P15056	BRAF	P15056	BRAF	T373	I374V	374	Missense	proximal	1	no	3.959	3.943	EPSD;PhosphoSitePlus	COSMIC	2.269	Down-regulation
TKL_RAF_RAF_BRAF_ST	P15056	BRAF	P15056	BRAF	T401	P407L	407	Missense	distal	6	no	2.275	2.231	EPSD	COSMIC	2.269	Loss
TKL_RAF_RAF_BRAF_ST	P15056	BRAF	P15056	BRAF	T401	A404V	404	Missense	distal	3	no	2.275	2.104	EPSD	COSMIC	2.269	Loss
TKL_RAF_RAF_BRAF_ST	P15056	BRAF	P15056	BRAF	T401	P403L	403	Missense	proximal	2	no	2.275	2.225	EPSD	COSMIC	2.269	Loss
TKL_RAF_RAF_BRAF_ST	P15056	BRAF	P15056	BRAF	T401	A400S	400	Missense	proximal	-1	no	2.275	2.326	EPSD	COSMIC	2.269	Up-regulation
TKL_RAF_RAF_BRAF_ST	P15056	BRAF	P15056	BRAF	S409	P407L	407	Missense	proximal	-2	no	2.381	2.267	EPSD	COSMIC	2.269	Loss
TKL_RAF_RAF_BRAF_ST	P15056	BRAF	P15056	BRAF	S409	A404V	404	Missense	distal	-5	no	2.381	2.295	EPSD	COSMIC	2.269	Down-regulation
TKL_RAF_RAF_BRAF_ST	P15056	BRAF	P15056	BRAF	S409	V413M	413	Missense	distal	4	no	2.381	2.364	EPSD	COSMIC	2.269	Down-regulation
TKL_RAF_RAF_BRAF_ST	P15056	BRAF	P15056	BRAF	S409	P403L	403	Missense	distal	-6	no	2.381	2.276	EPSD	COSMIC	2.269	Down-regulation
TKL_RAF_RAF_BRAF_ST	P15056	BRAF	P15056	BRAF	S409	N412S	412	Missense	distal	3	no	2.381	2.394	EPSD	COSMIC	2.269	Up-regulation
TKL_RAF_RAF_BRAF_ST	P15056	BRAF	P15056	BRAF	S409	L416S	416	Missense	distal	7	no	2.381	1.982	EPSD	COSMIC	2.269	Loss
TKL_RAF_RAF_BRAF_ST	P15056	BRAF	P15056	BRAF	S428	G421R	421	Missense	distal	-7	no	2.410	2.391	EPSD	COSMIC	2.269	Down-regulation
TKL_RAF_RAF_BRAF_ST	P15056	BRAF	P15056	BRAF	S428	G421V	421	Missense	distal	-7	no	2.410	2.394	EPSD	COSMIC	2.269	Down-regulation
TKL_RAF_RAF_BRAF_ST	P15056	BRAF	P15056	BRAF	S428	P422A	422	Missense	distal	-6	no	2.410	2.366	EPSD	COSMIC	2.269	Down-regulation
TKL_RAF_RAF_BRAF_ST	P15056	BRAF	P15056	BRAF	S428	S428L	428	Missense	central	0	yes	2.410	0.000	EPSD	COSMIC	2.269	Loss
TKL_RAF_RAF_BRAF_ST	P15056	BRAF	P15056	BRAF	S428	R424L	424	Missense	distal	-4	no	2.410	2.472	EPSD	COSMIC	2.269	Up-regulation
TKL_RAF_RAF_BRAF_ST	P15056	BRAF	P15056	BRAF	T440	S447N	447	Missense	distal	7	no	2.323	2.423	EPSD	COSMIC	2.269	Up-regulation
TKL_RAF_RAF_BRAF_ST	P15056	BRAF	P15056	BRAF	T440	R443I	443	Missense	distal	3	no	2.323	2.213	EPSD	COSMIC	2.269	Loss
TKL_RAF_RAF_BRAF_ST	P15056	BRAF	P15056	BRAF	T440	R443T	443	Missense	distal	3	no	2.323	2.278	EPSD	COSMIC	2.269	Down-regulation
TKL_RAF_RAF_BRAF_ST	P15056	BRAF	P15056	BRAF	T440	K439T	439	Missense	proximal	-1	no	2.323	2.237	EPSD	COSMIC	2.269	Loss
TKL_RAF_RAF_BRAF_ST	P15056	BRAF	P15056	BRAF	T440	G442S	442	Missense	proximal	2	no	2.323	2.356	EPSD	COSMIC	2.269	Up-regulation
TKL_RAF_RAF_BRAF_ST	P15056	BRAF	P15056	BRAF	T440	T440P	440	Missense	central	0	yes	2.323	0.000	EPSD	COSMIC	2.269	Loss
TKL_RAF_RAF_BRAF_ST	P15056	BRAF	P15056	BRAF	T440	L441V	441	Missense	proximal	1	no	2.323	2.303	EPSD	COSMIC	2.269	Down-regulation
TKL_RAF_RAF_BRAF_ST	P15056	BRAF	P15056	BRAF	T440	K439Q	439	Missense	proximal	-1	no	2.323	2.277	EPSD	COSMIC	2.269	Down-regulation
TKL_RAF_RAF_BRAF_ST	P15056	BRAF	P15056	BRAF	T440	S447C	447	Missense	distal	7	no	2.323	2.585	EPSD	COSMIC	2.269	Up-regulation
TKL_RAF_RAF_BRAF_ST	P15056	BRAF	P15056	BRAF	T440	G442D	442	Missense	proximal	2	no	2.323	2.358	EPSD	COSMIC	2.269	Up-regulation
TKL_RAF_RAF_BRAF_ST	P15056	BRAF	P15056	BRAF	T440	T440I	440	Missense	central	0	yes	2.323	0.000	EPSD	COSMIC	2.269	Loss
TKL_RAF_RAF_BRAF_ST	P15056	BRAF	P15056	BRAF	S446	T440P	440	Missense	distal	-6	no	2.213	2.442	EPSD	COSMIC	2.269	Gain
TKL_RAF_RAF_BRAF_ST	P15056	BRAF	P15056	BRAF	S446	T440I	440	Missense	distal	-6	no	2.213	2.385	EPSD	COSMIC	2.269	Gain
TKL_RAF_RAF_BRAF_ST	P15056	BRAF	P15056	BRAF	S447	R443I	443	Missense	distal	-4	no	1.853	2.269	EPSD	COSMIC	2.269	Gain
TKL_RAF_RAF_BRAF_ST	P15056	BRAF	P15056	BRAF	S614	L618S	618	Missense	distal	4	no	4.305	4.390	PhosphoSitePlus;EPSD	COSMIC	2.269	Up-regulation
TKL_RAF_RAF_BRAF_ST	P15056	BRAF	P15056	BRAF	S614	S616F	616	Missense	proximal	2	no	4.305	4.183	PhosphoSitePlus;EPSD	COSMIC	2.269	Down-regulation
TKL_RAF_RAF_BRAF_ST	P15056	BRAF	P15056	BRAF	S614	G615R	615	Missense	proximal	1	no	4.305	4.317	PhosphoSitePlus;EPSD	COSMIC	2.269	Up-regulation
TKL_RAF_RAF_BRAF_ST	P15056	BRAF	P15056	BRAF	S614	L618W	618	Missense	distal	4	no	4.305	4.294	PhosphoSitePlus;EPSD	COSMIC	2.269	Down-regulation
TKL_RAF_RAF_BRAF_ST	P15056	BRAF	P15056	BRAF	S614	M620I	620	Missense	distal	6	no	4.305	4.339	PhosphoSitePlus;EPSD	COSMIC	2.269	Up-regulation
TKL_RAF_RAF_BRAF_ST	P15056	BRAF	P15056	BRAF	S614	F610S	610	Missense	distal	-4	no	4.305	3.904	PhosphoSitePlus;EPSD	COSMIC	2.269	Down-regulation
TKL_RAF_RAF_BRAF_ST	P15056	BRAF	P15056	BRAF	S614	Q609R	609	Missense	distal	-5	no	4.305	4.296	PhosphoSitePlus;EPSD	COSMIC	2.269	Down-regulation
TKL_RAF_RAF_BRAF_ST	P15056	BRAF	P15056	BRAF	S614	E611D	611	Missense	distal	-3	no	4.305	4.440	PhosphoSitePlus;EPSD	COSMIC	2.269	Up-regulation
TKL_RAF_RAF_BRAF_ST	P15056	BRAF	P15056	BRAF	S614	Q612R	612	Missense	proximal	-2	no	4.305	4.495	PhosphoSitePlus;EPSD	COSMIC	2.269	Up-regulation
TKL_RAF_RAF_BRAF_ST	P15056	BRAF	P15056	BRAF	S614	F610I	610	Missense	distal	-4	no	4.305	4.555	PhosphoSitePlus;EPSD	COSMIC	2.269	Up-regulation
TKL_RAF_RAF_BRAF_ST	P15056	BRAF	P15056	BRAF	S614	S607F	607	Missense	distal	-7	no	4.305	4.242	PhosphoSitePlus;EPSD	COSMIC	2.269	Down-regulation
TKL_RAF_RAF_BRAF_ST	P15056	BRAF	P15056	BRAF	S614	S616P	616	Missense	proximal	2	no	4.305	4.298	PhosphoSitePlus;EPSD	COSMIC	2.269	Down-regulation
TKL_RAF_RAF_BRAF_ST	P15056	BRAF	P15056	BRAF	S614	S614F	614	Missense	central	0	yes	4.305	0.000	PhosphoSitePlus;EPSD	COSMIC	2.269	Loss
TKL_RAF_RAF_BRAF_ST	P15056	BRAF	P15056	BRAF	S614	H608R	608	Missense	distal	-6	no	4.305	4.301	PhosphoSitePlus;EPSD	COSMIC	2.269	Down-regulation
TKL_RAF_RAF_BRAF_ST	P15056	BRAF	P15056	BRAF	S614	Q612E	612	Missense	proximal	-2	no	4.305	4.346	PhosphoSitePlus;EPSD	COSMIC	2.269	Up-regulation
TKL_RAF_RAF_BRAF_ST	P15056	BRAF	P15056	BRAF	S614	S607P	607	Missense	distal	-7	no	4.305	4.280	PhosphoSitePlus;EPSD	COSMIC	2.269	Down-regulation
TKL_RAF_RAF_BRAF_ST	P15056	BRAF	P15056	BRAF	S614	I617T	617	Missense	distal	3	no	4.305	4.370	PhosphoSitePlus;EPSD	COSMIC	2.269	Up-regulation
TKL_RAF_RAF_BRAF_ST	P15056	BRAF	P15056	BRAF	S614	H608L	608	Missense	distal	-6	no	4.305	4.148	PhosphoSitePlus;EPSD	COSMIC	2.269	Down-regulation
TKL_RAF_RAF_BRAF_ST	P15056	BRAF	P15056	BRAF	S614	H608Y	608	Missense	distal	-6	no	4.305	3.972	PhosphoSitePlus;EPSD	COSMIC	2.269	Down-regulation
TKL_RAF_RAF_BRAF_ST	P15056	BRAF	P15056	BRAF	S614	W619R	619	Missense	distal	5	no	4.305	4.163	PhosphoSitePlus;EPSD	COSMIC	2.269	Down-regulation
TKL_RAF_RAF_BRAF_ST	P15056	BRAF	P15056	BRAF	S614	H608D	608	Missense	distal	-6	no	4.305	4.020	PhosphoSitePlus;EPSD	COSMIC	2.269	Down-regulation
TKL_RAF_RAF_BRAF_ST	P15056	BRAF	P15056	BRAF	S614	S614Y	614	Missense	central	0	yes	4.305	0.000	PhosphoSitePlus;EPSD	COSMIC	2.269	Loss
TKL_RAF_RAF_BRAF_ST	P15056	BRAF	P15056	BRAF	S675	K680N	680	Missense	distal	5	no	2.088	2.298	EPSD	COSMIC	2.269	Gain
TKL_RAF_RAF_BRAF_ST	Q02750	MAP2K1	P15056	BRAF	S212	S212N	212	Missense	central	0	yes	2.283	0.000	EPSD	COSMIC	2.269	Loss
TKL_RAF_RAF_BRAF_ST	Q02750	MAP2K1	P15056	BRAF	S212	L215F	215	Missense	distal	3	no	2.283	2.333	EPSD	COSMIC	2.269	Up-regulation
TKL_RAF_RAF_BRAF_ST	Q02750	MAP2K1	P15056	BRAF	S212	G213V	213	Missense	proximal	1	no	2.283	2.265	EPSD	COSMIC	2.269	Loss
TKL_RAF_RAF_BRAF_ST	Q02750	MAP2K1	P15056	BRAF	S212	L206F	206	Missense	distal	-6	no	2.283	2.354	EPSD	COSMIC	2.269	Up-regulation
TKL_RAF_RAF_BRAF_ST	Q02750	MAP2K1	P15056	BRAF	S212	S218F	218	Missense	distal	6	no	2.283	2.347	EPSD	COSMIC	2.269	Up-regulation
TKL_RAF_RAF_BRAF_ST	Q02750	MAP2K1	P15056	BRAF	S218	S212N	212	Missense	distal	-6	no	4.261	4.454	EPSD;PhosphoSitePlus	COSMIC	2.269	Up-regulation
TKL_RAF_RAF_BRAF_ST	Q02750	MAP2K1	P15056	BRAF	S218	L215F	215	Missense	distal	-3	no	4.261	4.085	EPSD;PhosphoSitePlus	COSMIC	2.269	Down-regulation
TKL_RAF_RAF_BRAF_ST	Q02750	MAP2K1	P15056	BRAF	S218	G213V	213	Missense	distal	-5	no	4.261	4.209	EPSD;PhosphoSitePlus	COSMIC	2.269	Down-regulation
TKL_RAF_RAF_BRAF_ST	Q02750	MAP2K1	P15056	BRAF	S218	S218F	218	Missense	central	0	yes	4.261	0.000	EPSD;PhosphoSitePlus	COSMIC	2.269	Loss
TKL_RAF_RAF_BRAF_ST	Q02750	MAP2K1	P15056	BRAF	S222	L215F	215	Missense	distal	-7	no	4.478	4.434	PhosphoSitePlus;EPSD	COSMIC	2.269	Down-regulation
TKL_RAF_RAF_BRAF_ST	Q02750	MAP2K1	P15056	BRAF	S222	Y229H	229	Missense	distal	7	no	4.478	4.558	PhosphoSitePlus;EPSD	COSMIC	2.269	Up-regulation
TKL_RAF_RAF_BRAF_ST	Q02750	MAP2K1	P15056	BRAF	S222	S218F	218	Missense	distal	-4	no	4.478	4.878	PhosphoSitePlus;EPSD	COSMIC	2.269	Up-regulation
TKL_RAF_RAF_BRAF_ST	Q05639	EEF1A2	P15056	BRAF	S21	G14D	14	Missense	distal	-7	no	4.317	4.323	PhosphoSitePlus	COSMIC	2.269	Up-regulation
TKL_RAF_RAF_BRAF_ST	Q05639	EEF1A2	P15056	BRAF	S224	S227F	227	Missense	distal	3	no	2.268	2.438	EPSD	COSMIC	2.269	Gain
TKL_RAF_RAF_BRAF_ST	Q05639	EEF1A2	P15056	BRAF	S396	E403K	403	Missense	distal	7	no	2.249	2.345	EPSD	COSMIC	2.269	Gain
TKL_RAF_RAF_BRAF_ST	P33981	TTK	P15056	BRAF	S436	T441I	441	Missense	distal	5	no	4.309	4.241	EPSD;PhosphoSitePlus	COSMIC	2.269	Down-regulation
TKL_RAF_RAF_BRAF_ST	P33981	TTK	P15056	BRAF	S742	I737T	737	Missense	distal	-5	no	2.176	2.304	EPSD	COSMIC	2.269	Gain
TKL_RAF_RAF_BRAF_ST	P33981	TTK	P15056	BRAF	S837	N843I	843	Missense	distal	6	no	2.494	2.556	EPSD	COSMIC	2.269	Up-regulation
TKL_RAF_RAF_BRAF_ST	P36507	MAP2K2	P15056	BRAF	S76	E73K	73	Missense	distal	-3	no	2.272	2.451	EPSD	COSMIC	2.269	Up-regulation
TKL_RAF_RAF_BRAF_ST	P36507	MAP2K2	P15056	BRAF	S76	G81D	81	Missense	distal	5	no	2.272	2.207	EPSD	COSMIC	2.269	Loss
TKL_RAF_RAF_BRAF_ST	P36507	MAP2K2	P15056	BRAF	S76	S76L	76	Missense	central	0	yes	2.272	0.000	EPSD	COSMIC	2.269	Loss
TKL_RAF_RAF_BRAF_ST	P36507	MAP2K2	P15056	BRAF	S76	D70N	70	Missense	distal	-6	no	2.272	2.449	EPSD	COSMIC	2.269	Up-regulation
TKL_RAF_RAF_BRAF_ST	P36507	MAP2K2	P15056	BRAF	S76	E77K	77	Missense	proximal	1	no	2.272	2.270	EPSD	COSMIC	2.269	Down-regulation
TKL_RAF_RAF_BRAF_ST	P36507	MAP2K2	P15056	BRAF	S222	G217C	217	Missense	distal	-5	no	4.451	4.410	EPSD;PhosphoSitePlus	COSMIC	2.269	Down-regulation
TKL_RAF_RAF_BRAF_ST	P36507	MAP2K2	P15056	BRAF	S222	S222Y	222	Missense	central	0	yes	4.451	0.000	EPSD;PhosphoSitePlus	COSMIC	2.269	Loss
TKL_RAF_RAF_BRAF_ST	P36507	MAP2K2	P15056	BRAF	S222	M223V	223	Missense	proximal	1	no	4.451	4.437	EPSD;PhosphoSitePlus	COSMIC	2.269	Down-regulation
TKL_RAF_RAF_BRAF_ST	P36507	MAP2K2	P15056	BRAF	S222	V215E	215	Missense	distal	-7	no	4.451	4.445	EPSD;PhosphoSitePlus	COSMIC	2.269	Down-regulation
TKL_RAF_RAF_BRAF_ST	P36507	MAP2K2	P15056	BRAF	S226	R231H	231	Missense	distal	5	no	4.058	4.293	PhosphoSitePlus;EPSD	COSMIC	2.269	Up-regulation
TKL_RAF_RAF_BRAF_ST	P36507	MAP2K2	P15056	BRAF	S226	S222Y	222	Missense	distal	-4	no	4.058	4.233	PhosphoSitePlus;EPSD	COSMIC	2.269	Up-regulation
TKL_RAF_RAF_BRAF_ST	P36507	MAP2K2	P15056	BRAF	S226	M223V	223	Missense	distal	-3	no	4.058	3.986	PhosphoSitePlus;EPSD	COSMIC	2.269	Down-regulation
Other_NEK_NEK9_NEK9_ST	Q8NHV4	NEDD1	Q8TD19	NEK9	S455	S455L	455	Missense	central	0	yes	3.005	0.000	EPSD	COSMIC;CCLE	2.671	Loss
Other_NEK_NEK9_NEK9_ST	Q8NHV4	NEDD1	Q8TD19	NEK9	S516	N520K	520	Missense	distal	4	no	2.474	2.815	EPSD	COSMIC	2.671	Gain
Other_NEK_NEK9_NEK9_ST	Q8NHV4	NEDD1	Q8TD19	NEK9	S518	N524I	524	Missense	distal	6	no	2.774	2.807	EPSD	COSMIC	2.671	Up-regulation
Other_NEK_NEK9_NEK9_ST	Q8NHV4	NEDD1	Q8TD19	NEK9	S518	T522A	522	Missense	distal	4	no	2.774	2.181	EPSD	COSMIC	2.671	Loss
Other_NEK_NEK9_NEK9_ST	Q8NHV4	NEDD1	Q8TD19	NEK9	S518	N520K	520	Missense	proximal	2	no	2.774	2.734	EPSD	COSMIC	2.671	Down-regulation
Other_NEK_NEK9_NEK9_ST	Q8NHV4	NEDD1	Q8TD19	NEK9	S518	S518L	518	Missense	central	0	yes	2.774	0.000	EPSD	COSMIC	2.671	Loss
Other_NEK_NEK9_NEK9_ST	Q8NHV4	NEDD1	Q8TD19	NEK9	S518	S525L	525	Missense	distal	7	no	2.774	2.678	EPSD	COSMIC	2.671	Down-regulation
Other_NEK_NEK9_NEK9_ST	Q8NHV4	NEDD1	Q8TD19	NEK9	S549	P551A	551	Missense	proximal	2	no	2.980	2.940	EPSD	COSMIC	2.671	Down-regulation
Other_NEK_NEK9_NEK9_ST	Q8NHV4	NEDD1	Q8TD19	NEK9	S566	A572V	572	Missense	distal	6	no	3.031	3.036	EPSD	COSMIC;CCLE	2.671	Up-regulation
Other_NEK_NEK9_NEK9_ST	Q8NHV4	NEDD1	Q8TD19	NEK9	S566	G562E	562	Missense	distal	-4	no	3.031	3.017	EPSD	COSMIC	2.671	Down-regulation
Other_NEK_NEK9_NEK9_ST	Q8TDX7	NEK7	Q8TD19	NEK9	T30	R35P	35	Missense	distal	5	no	2.344	3.329	EPSD	COSMIC	2.671	Gain
Other_NEK_NEK9_NEK9_ST	Q8TDX7	NEK7	Q8TD19	NEK9	S195	Y201H	201	Missense	distal	6	no	8.327	8.325	PhosphoSitePlus	COSMIC	2.671	Down-regulation
Other_NEK_NEK9_NEK9_ST	Q8TD19	NEK9	Q8TD19	NEK9	S76	V78L	78	Missense	proximal	2	no	3.201	3.247	EPSD	COSMIC	2.671	Up-regulation
Other_NEK_NEK9_NEK9_ST	Q8TD19	NEK9	Q8TD19	NEK9	S206	K199N	199	Missense	distal	-7	no	2.959	2.949	EPSD	COSMIC	2.671	Down-regulation
Other_NEK_NEK9_NEK9_ST	Q8TD19	NEK9	Q8TD19	NEK9	S331	P325H	325	Missense	distal	-6	no	4.085	3.339	EPSD	COSMIC	2.671	Down-regulation
Other_NEK_NEK9_NEK9_ST	Q8TD19	NEK9	Q8TD19	NEK9	S836	E839Q	839	Missense	distal	3	no	3.338	3.359	EPSD	COSMIC	2.671	Up-regulation
Other_NEK_NEK9_NEK9_ST	Q8TD19	NEK9	Q8TD19	NEK9	S869	P874S	874	Missense	distal	5	no	2.774	1.802	EPSD	COSMIC	2.671	Loss
Other_NEK_NEK9_NEK9_ST	Q8TD19	NEK9	Q8TD19	NEK9	S869	P870S	870	Missense	proximal	1	no	2.774	2.960	EPSD	COSMIC;GDSC;CCLE	2.671	Up-regulation
Other_NEK_NEK9_NEK9_ST	Q8TD19	NEK9	Q8TD19	NEK9	S869	P874H	874	Missense	distal	5	no	2.774	2.047	EPSD	COSMIC;GDSC;CCLE	2.671	Loss
Other_NEK_NEK9_NEK9_ST	Q8TD19	NEK9	Q8TD19	NEK9	S944	M942K	942	Missense	proximal	-2	no	8.113	8.162	PhosphoSitePlus;EPSD	COSMIC	2.671	Up-regulation
Other_NEK_NEK9_NEK9_ST	Q8TD19	NEK9	Q8TD19	NEK9	T949	M942K	942	Missense	distal	-7	no	2.783	2.789	EPSD	COSMIC	2.671	Up-regulation
Other_NEK_NEK9_NEK9_ST	Q8TD19	NEK9	Q8TD19	NEK9	S964	S966F	966	Missense	proximal	2	no	2.755	2.751	EPSD	COSMIC	2.671	Down-regulation
Other_NEK_NEK9_NEK9_ST	Q8TD19	NEK9	Q8TD19	NEK9	S964	L970P	970	Missense	distal	6	no	2.755	2.772	EPSD	COSMIC;GDSC;CCLE	2.671	Up-regulation
Other_NEK_NEK9_NEK9_ST	Q8TD19	NEK9	Q8TD19	NEK9	S966	S966F	966	Missense	central	0	yes	3.066	0.000	EPSD	COSMIC	2.671	Loss
Other_NEK_NEK9_NEK9_ST	Q8TD19	NEK9	Q8TD19	NEK9	S966	L970P	970	Missense	distal	4	no	3.066	3.709	EPSD	COSMIC;GDSC;CCLE	2.671	Up-regulation
Other_NEK_NEK9_NEK9_ST	Q9HC98	NEK6	Q8TD19	NEK9	T35	N34D	34	Missense	proximal	-1	no	3.825	3.994	EPSD	COSMIC	2.671	Up-regulation
Other_NEK_NEK9_NEK9_ST	Q9HC98	NEK6	Q8TD19	NEK9	T35	S41L	41	Missense	distal	6	no	3.825	3.829	EPSD	COSMIC	2.671	Up-regulation
Other_NEK_NEK9_NEK9_ST	Q9HC98	NEK6	Q8TD19	NEK9	T35	N34K	34	Missense	proximal	-1	no	3.825	4.324	EPSD	COSMIC	2.671	Up-regulation
Other_NEK_NEK9_NEK9_ST	Q9HC98	NEK6	Q8TD19	NEK9	S206	A203T	203	Missense	distal	-3	no	8.354	8.315	PhosphoSitePlus	COSMIC;CCLE	2.671	Down-regulation
Other_NEK_NEK9_NEK9_ST	Q9HC98	NEK6	Q8TD19	NEK9	S206	T201N	201	Missense	distal	-5	no	8.354	8.274	PhosphoSitePlus	COSMIC	2.671	Down-regulation
Other_NEK_NEK9_NEK9_ST	Q9HC98	NEK6	Q8TD19	NEK9	S206	G209S	209	Missense	distal	3	no	8.354	8.357	PhosphoSitePlus	COSMIC	2.671	Up-regulation
CAMK_MLCK_MYLK_ST	O14950	MYL12B	Q15746	MYLK	T19	M25L	25	Missense	distal	6	no	1.827	1.828	EPSD;PhosphoSitePlus	COSMIC	1.165	Up-regulation
CAMK_MLCK_MYLK_ST	O14950	MYL12B	Q15746	MYLK	T19	K12N	12	Missense	distal	-7	no	1.827	1.608	EPSD;PhosphoSitePlus	COSMIC	1.165	Down-regulation
CAMK_MLCK_MYLK_ST	O14950	MYL12B	Q15746	MYLK	S20	M25L	25	Missense	distal	5	no	1.417	1.397	PhosphoSitePlus;EPSD	COSMIC	1.165	Down-regulation
CAMK_MLCK_MYLK_ST	O14950	MYL12B	Q15746	MYLK	T160	F159S	159	Missense	proximal	-1	no	1.182	1.173	EPSD	COSMIC	1.165	Down-regulation
CAMK_MLCK_MYLK_ST	P10916	MYL2	Q15746	MYLK	S15	N16Y	16	Missense	proximal	1	no	1.569	1.574	PhosphoSitePlus	COSMIC	1.165	Up-regulation
CAMK_MLCK_MYLK_ST	P10916	MYL2	Q15746	MYLK	S15	K8R	8	Missense	distal	-7	no	1.569	1.443	PhosphoSitePlus	COSMIC	1.165	Down-regulation
CAMK_MLCK_MYLK_ST	P10916	MYL2	Q15746	MYLK	T98	A102T	102	Missense	distal	4	no	1.295	1.206	EPSD	COSMIC;GDSC;CCLE	1.165	Down-regulation
CAMK_MLCK_MYLK_ST	P10916	MYL2	Q15746	MYLK	T98	E96K	96	Missense	proximal	-2	no	1.295	1.284	EPSD	COSMIC	1.165	Down-regulation
CAMK_MLCK_MYLK_ST	P10916	MYL2	Q15746	MYLK	T98	D94N	94	Missense	distal	-4	no	1.295	1.285	EPSD	COSMIC;GDSC;CCLE	1.165	Down-regulation
CAMK_MLCK_MYLK_ST	P10916	MYL2	Q15746	MYLK	T98	G92A	92	Missense	distal	-6	no	1.295	1.270	EPSD	COSMIC	1.165	Down-regulation
CAMK_MLCK_MYLK_ST	P10916	MYL2	Q15746	MYLK	T98	E97A	97	Missense	proximal	-1	no	1.295	1.299	EPSD	COSMIC	1.165	Up-regulation
CAMK_MLCK_MYLK_ST	P10916	MYL2	Q15746	MYLK	T98	K91N	91	Missense	distal	-7	no	1.295	1.076	EPSD	COSMIC	1.165	Loss
CAMK_MLCK_MYLK_ST	P24844	MYL9	Q15746	MYLK	T19	N21T	21	Missense	proximal	2	no	1.797	1.758	PhosphoSitePlus;EPSD	COSMIC	1.165	Down-regulation
CAMK_MLCK_MYLK_ST	P24844	MYL9	Q15746	MYLK	T19	P15S	15	Missense	distal	-4	no	1.797	1.779	PhosphoSitePlus;EPSD	COSMIC	1.165	Down-regulation
CAMK_MLCK_MYLK_ST	P24844	MYL9	Q15746	MYLK	T19	R14Q	14	Missense	distal	-5	no	1.797	1.648	PhosphoSitePlus;EPSD	COSMIC	1.165	Down-regulation
CAMK_MLCK_MYLK_ST	P24844	MYL9	Q15746	MYLK	S20	N21T	21	Missense	proximal	1	no	1.446	1.459	EPSD;PhosphoSitePlus	COSMIC	1.165	Up-regulation
CAMK_MLCK_MYLK_ST	P24844	MYL9	Q15746	MYLK	S20	P15S	15	Missense	distal	-5	no	1.446	1.428	EPSD;PhosphoSitePlus	COSMIC	1.165	Down-regulation
CAMK_MLCK_MYLK_ST	P24844	MYL9	Q15746	MYLK	S20	R14Q	14	Missense	distal	-6	no	1.446	1.322	EPSD;PhosphoSitePlus	COSMIC	1.165	Down-regulation
AGC_PKC_PKCa_PRKCG_ST	P07900	HSP90AA1	P05129	PRKCG	T7	E4G	4	Missense	distal	-3	no	109.654	110.764	EPSD	COSMIC	98.543	Up-regulation
AGC_PKC_PKCa_PRKCG_ST	P07900	HSP90AA1	P05129	PRKCG	T19	V17I	17	Missense	proximal	-2	no	108.390	95.518	EPSD	COSMIC	98.543	Loss
AGC_PKC_PKCa_PRKCG_ST	P07900	HSP90AA1	P05129	PRKCG	S63	K58T	58	Missense	distal	-5	no	102.767	102.884	EPSD	COSMIC	98.543	Up-regulation
AGC_PKC_PKCa_PRKCG_ST	P07900	HSP90AA1	P05129	PRKCG	S72	I78F	78	Missense	distal	6	no	104.224	106.113	EPSD	COSMIC	98.543	Up-regulation
AGC_PKC_PKCa_PRKCG_ST	P07900	HSP90AA1	P05129	PRKCG	T293	N300S	300	Missense	distal	7	no	108.463	95.223	EPSD	COSMIC	98.543	Loss
AGC_PKC_PKCa_PRKCG_ST	P07900	HSP90AA1	P05129	PRKCG	S330	S330L	330	Missense	central	0	yes	101.577	0.000	EPSD	COSMIC	98.543	Loss
AGC_PKC_PKCa_PRKCG_ST	P07900	HSP90AA1	P05129	PRKCG	S391	D393N	393	Missense	proximal	2	no	79.817	101.847	EPSD	COSMIC;CCLE	98.543	Gain
AGC_PKC_PKCa_PRKCG_ST	P07900	HSP90AA1	P05129	PRKCG	T425	K418I	418	Missense	distal	-7	no	113.801	109.567	EPSD;PhosphoSitePlus	COSMIC	98.543	Down-regulation
AGC_PKC_PKCa_PRKCG_ST	P07900	HSP90AA1	P05129	PRKCG	T425	L423V	423	Missense	proximal	-2	no	113.801	114.555	EPSD;PhosphoSitePlus	COSMIC	98.543	Up-regulation
AGC_PKC_PKCa_PRKCG_ST	P07900	HSP90AA1	P05129	PRKCG	S460	E461K	461	Missense	proximal	1	no	112.598	119.132	EPSD	COSMIC	98.543	Up-regulation
AGC_PKC_PKCa_PRKCG_ST	P07900	HSP90AA1	P05129	PRKCG	S460	S453C	453	Missense	distal	-7	no	112.598	108.946	EPSD	COSMIC	98.543	Down-regulation
AGC_PKC_PKCa_PRKCG_ST	P07900	HSP90AA1	P05129	PRKCG	S476	S470C	470	Missense	distal	-6	no	112.123	108.231	EPSD	COSMIC;CCLE	98.543	Down-regulation
AGC_PKC_PKCa_PRKCG_ST	P07900	HSP90AA1	P05129	PRKCG	S476	C481G	481	Missense	distal	5	no	112.123	109.650	EPSD	COSMIC	98.543	Down-regulation
AGC_PKC_PKCa_PRKCG_ST	P07900	HSP90AA1	P05129	PRKCG	S476	G471V	471	Missense	distal	-5	no	112.123	114.686	EPSD	COSMIC	98.543	Up-regulation
AGC_PKC_PKCa_PRKCG_ST	P07900	HSP90AA1	P05129	PRKCG	S476	D472N	472	Missense	distal	-4	no	112.123	111.375	EPSD	COSMIC	98.543	Down-regulation
AGC_PKC_PKCa_PRKCG_ST	P07900	HSP90AA1	P05129	PRKCG	T603	P596S	596	Missense	distal	-7	no	124.768	127.050	EPSD;PhosphoSitePlus	COSMIC;CCLE	98.543	Up-regulation
AGC_PKC_PKCa_PRKCG_ST	P07900	HSP90AA1	P05129	PRKCG	T645	I643F	643	Missense	proximal	-2	no	95.739	98.975	EPSD	COSMIC	98.543	Gain
AGC_PKC_PKCa_PRKCG_ST	P07900	HSP90AA1	P05129	PRKCG	T645	I643T	643	Missense	proximal	-2	no	95.739	109.570	EPSD	COSMIC	98.543	Gain
AGC_PKC_PKCa_PRKCG_ST	Q9H3Z4	DNAJC5	P05129	PRKCG	S10	Y17H	17	Missense	distal	7	no	128.222	128.270	EPSD;PhosphoSitePlus	COSMIC	98.543	Up-regulation
AGC_PKC_PKCa_PRKCG_ST	Q9H3Z4	DNAJC5	P05129	PRKCG	T11	Y17H	17	Missense	distal	6	no	108.632	110.379	EPSD	COSMIC	98.543	Up-regulation
AGC_PKC_PKCa_PRKCG_ST	Q9H3Z4	DNAJC5	P05129	PRKCG	S15	Y17H	17	Missense	proximal	2	no	105.998	106.943	EPSD	COSMIC	98.543	Up-regulation
AGC_PKC_PKCa_PRKCG_ST	Q9H3Z4	DNAJC5	P05129	PRKCG	S15	L20F	20	Missense	distal	5	no	105.998	111.153	EPSD	COSMIC	98.543	Up-regulation
AGC_PKC_PKCa_PRKCG_ST	Q9H3Z4	DNAJC5	P05129	PRKCG	T146	A140V	140	Missense	distal	-6	no	107.427	102.315	EPSD	COSMIC;GDSC;CCLE	98.543	Down-regulation
AGC_PKC_PKCa_PRKCG_ST	P10636	MAPT	P05129	PRKCG	T167	E165K	165	Missense	proximal	-2	no	82.733	101.987	EPSD	COSMIC	98.543	Gain
AGC_PKC_PKCa_PRKCG_ST	P10636	MAPT	P05129	PRKCG	S341	A337T	337	Missense	distal	-4	no	119.427	119.623	EPSD	COSMIC	98.543	Up-regulation
AGC_PKC_PKCa_PRKCG_ST	P10636	MAPT	P05129	PRKCG	S341	G343R	343	Missense	proximal	2	no	119.427	141.073	EPSD	COSMIC	98.543	Up-regulation
AGC_PKC_PKCa_PRKCG_ST	P10636	MAPT	P05129	PRKCG	S341	D345G	345	Missense	distal	4	no	119.427	115.833	EPSD	COSMIC	98.543	Down-regulation
AGC_PKC_PKCa_PRKCG_ST	P10636	MAPT	P05129	PRKCG	S341	K347N	347	Missense	distal	6	no	119.427	118.293	EPSD	COSMIC	98.543	Down-regulation
AGC_PKC_PKCa_PRKCG_ST	P10636	MAPT	P05129	PRKCG	S355	A361S	361	Missense	distal	6	no	100.712	98.710	EPSD	COSMIC;GDSC;CCLE	98.543	Down-regulation
AGC_PKC_PKCa_PRKCG_ST	P10636	MAPT	P05129	PRKCG	S355	P354L	354	Missense	proximal	-1	no	100.712	101.206	EPSD	COSMIC	98.543	Up-regulation
AGC_PKC_PKCa_PRKCG_ST	P10636	MAPT	P05129	PRKCG	S388	D389N	389	Missense	proximal	1	no	94.071	104.070	EPSD	COSMIC;GDSC;CCLE	98.543	Gain
AGC_PKC_PKCa_PRKCG_ST	P10636	MAPT	P05129	PRKCG	S531	R526H	526	Missense	distal	-5	no	99.229	101.804	EPSD	COSMIC	98.543	Up-regulation
AGC_PKC_PKCa_PRKCG_ST	P10636	MAPT	P05129	PRKCG	S531	R528S	528	Missense	distal	-3	no	99.229	86.484	EPSD	COSMIC	98.543	Loss
AGC_PKC_PKCa_PRKCG_ST	P10636	MAPT	P05129	PRKCG	S531	P530S	530	Missense	proximal	-1	no	99.229	104.294	EPSD	COSMIC	98.543	Up-regulation
AGC_PKC_PKCa_PRKCG_ST	P10636	MAPT	P05129	PRKCG	S531	P536H	536	Missense	distal	5	no	99.229	96.021	EPSD	COSMIC	98.543	Loss
AGC_PKC_PKCa_PRKCG_ST	P10636	MAPT	P05129	PRKCG	S531	P535Q	535	Missense	distal	4	no	99.229	103.045	EPSD	COSMIC	98.543	Up-regulation
AGC_PKC_PKCa_PRKCG_ST	P10636	MAPT	P05129	PRKCG	S555	P550S	550	Missense	distal	-5	no	99.853	96.596	EPSD	COSMIC	98.543	Loss
AGC_PKC_PKCa_PRKCG_ST	P10636	MAPT	P05129	PRKCG	S555	R559C	559	Missense	distal	4	no	99.853	87.680	EPSD	COSMIC	98.543	Loss
AGC_PKC_PKCa_PRKCG_ST	P10636	MAPT	P05129	PRKCG	S555	P553R	553	Missense	proximal	-2	no	99.853	113.463	EPSD	COSMIC	98.543	Up-regulation
AGC_PKC_PKCa_PRKCG_ST	P10636	MAPT	P05129	PRKCG	S555	P553L	553	Missense	proximal	-2	no	99.853	106.986	EPSD	COSMIC	98.543	Up-regulation
AGC_PKC_PKCa_PRKCG_ST	P10636	MAPT	P05129	PRKCG	S555	P549L	549	Missense	distal	-6	no	99.853	98.351	EPSD	COSMIC	98.543	Loss
AGC_PKC_PKCa_PRKCG_ST	P10636	MAPT	P05129	PRKCG	S555	S555F	555	Missense	central	0	yes	99.853	0.000	EPSD	COSMIC	98.543	Loss
AGC_PKC_PKCa_PRKCG_ST	P10636	MAPT	P05129	PRKCG	S555	P553Q	553	Missense	proximal	-2	no	99.853	105.076	EPSD	COSMIC	98.543	Up-regulation
AGC_PKC_PKCa_PRKCG_ST	P10636	MAPT	P05129	PRKCG	T562	V565M	565	Missense	distal	3	no	112.590	111.772	EPSD	COSMIC	98.543	Down-regulation
AGC_PKC_PKCa_PRKCG_ST	P10636	MAPT	P05129	PRKCG	T562	P566S	566	Missense	distal	4	no	112.590	112.910	EPSD	COSMIC	98.543	Up-regulation
AGC_PKC_PKCa_PRKCG_ST	P10636	MAPT	P05129	PRKCG	T562	R559C	559	Missense	distal	-3	no	112.590	85.017	EPSD	COSMIC	98.543	Loss
AGC_PKC_PKCa_PRKCG_ST	P10636	MAPT	P05129	PRKCG	T562	S555F	555	Missense	distal	-7	no	112.590	111.894	EPSD	COSMIC	98.543	Down-regulation
AGC_PKC_PKCa_PRKCG_ST	P10636	MAPT	P05129	PRKCG	T562	P568S	568	Missense	distal	6	no	112.590	108.721	EPSD	COSMIC	98.543	Down-regulation
AGC_PKC_PKCa_PRKCG_ST	P10636	MAPT	P05129	PRKCG	S575	T580N	580	Missense	distal	5	no	124.683	120.601	EPSD	COSMIC	98.543	Down-regulation
AGC_PKC_PKCa_PRKCG_ST	P10636	MAPT	P05129	PRKCG	S575	G578S	578	Missense	distal	3	no	124.683	112.827	EPSD	COSMIC	98.543	Down-regulation
AGC_PKC_PKCa_PRKCG_ST	P10636	MAPT	P05129	PRKCG	S575	K571E	571	Missense	distal	-4	no	124.683	123.104	EPSD	COSMIC	98.543	Down-regulation
AGC_PKC_PKCa_PRKCG_ST	P10636	MAPT	P05129	PRKCG	S575	P568S	568	Missense	distal	-7	no	124.683	126.965	EPSD	COSMIC	98.543	Up-regulation
AGC_PKC_PKCa_PRKCG_ST	P10636	MAPT	P05129	PRKCG	S606	C608W	608	Missense	proximal	2	no	82.565	99.011	EPSD	COSMIC	98.543	Gain
AGC_PKC_PKCa_PRKCG_ST	P10636	MAPT	P05129	PRKCG	S610	N613D	613	Missense	distal	3	no	125.450	118.289	EPSD	COSMIC	98.543	Down-regulation
AGC_PKC_PKCa_PRKCG_ST	P10636	MAPT	P05129	PRKCG	S610	C608W	608	Missense	proximal	-2	no	125.450	118.458	EPSD	COSMIC	98.543	Down-regulation
AGC_PKC_PKCa_PRKCG_ST	P10636	MAPT	P05129	PRKCG	S610	S610L	610	Missense	central	0	yes	125.450	0.000	EPSD	COSMIC	98.543	Loss
AGC_PKC_PKCa_PRKCG_ST	P10636	MAPT	P05129	PRKCG	S641	H647Y	647	Missense	distal	6	no	129.817	128.070	EPSD	COSMIC	98.543	Down-regulation
AGC_PKC_PKCa_PRKCG_ST	P10636	MAPT	P05129	PRKCG	S658	D662G	662	Missense	distal	4	no	102.617	99.023	EPSD	COSMIC	98.543	Down-regulation
AGC_PKC_PKCa_PRKCG_ST	P10636	MAPT	P05129	PRKCG	S658	K664N	664	Missense	distal	6	no	102.617	101.483	EPSD	COSMIC	98.543	Down-regulation
AGC_PKC_PKCa_PRKCG_ST	P10636	MAPT	P05129	PRKCG	S669	S669L	669	Missense	central	0	yes	137.382	0.000	EPSD	COSMIC	98.543	Loss
AGC_PKC_PKCa_PRKCG_ST	P10636	MAPT	P05129	PRKCG	S669	R666K	666	Missense	distal	-3	no	137.382	135.816	EPSD	COSMIC	98.543	Down-regulation
AGC_PKC_PKCa_PRKCG_ST	P10636	MAPT	P05129	PRKCG	S669	D662G	662	Missense	distal	-7	no	137.382	135.042	EPSD	COSMIC	98.543	Down-regulation
AGC_PKC_PKCa_PRKCG_ST	P10636	MAPT	P05129	PRKCG	S669	S673F	673	Missense	distal	4	no	137.382	142.474	EPSD	COSMIC	98.543	Up-regulation
AGC_PKC_PKCa_PRKCG_ST	P10636	MAPT	P05129	PRKCG	S669	K670N	670	Missense	proximal	1	no	137.382	134.328	EPSD	COSMIC	98.543	Down-regulation
AGC_PKC_PKCa_PRKCG_ST	P10636	MAPT	P05129	PRKCG	S669	K664N	664	Missense	distal	-5	no	137.382	138.463	EPSD	COSMIC	98.543	Up-regulation
AGC_PKC_PKCa_PRKCG_ST	P10636	MAPT	P05129	PRKCG	S669	L674Q	674	Missense	distal	5	no	137.382	146.501	EPSD	COSMIC	98.543	Up-regulation
AGC_PKC_PKCa_PRKCG_ST	P10636	MAPT	P05129	PRKCG	T690	R696H	696	Missense	distal	6	no	103.490	100.316	EPSD	COSMIC	98.543	Down-regulation
AGC_PKC_PKCa_PRKCG_ST	P10636	MAPT	P05129	PRKCG	T690	G683R	683	Missense	distal	-7	no	103.490	104.243	EPSD	COSMIC;CCLE	98.543	Up-regulation
AGC_PKC_PKCa_PRKCG_ST	P10636	MAPT	P05129	PRKCG	T690	G683E	683	Missense	distal	-7	no	103.490	102.867	EPSD	COSMIC	98.543	Down-regulation
AGC_PKC_PKCa_PRKCG_ST	P10636	MAPT	P05129	PRKCG	T690	R696C	696	Missense	distal	6	no	103.490	96.698	EPSD	COSMIC	98.543	Loss
AGC_PKC_PKCa_PRKCG_ST	P10636	MAPT	P05129	PRKCG	T690	G684E	684	Missense	distal	-6	no	103.490	102.272	EPSD	COSMIC	98.543	Down-regulation
AGC_PKC_PKCa_PRKCG_ST	P10636	MAPT	P05129	PRKCG	T694	R696H	696	Missense	proximal	2	no	139.644	113.868	EPSD	COSMIC	98.543	Down-regulation
AGC_PKC_PKCa_PRKCG_ST	P10636	MAPT	P05129	PRKCG	T694	R696C	696	Missense	proximal	2	no	139.644	92.745	EPSD	COSMIC	98.543	Loss
AGC_PKC_PKCa_PRKCG_ST	P10636	MAPT	P05129	PRKCG	S721	R723W	723	Missense	proximal	2	no	100.732	70.278	EPSD	COSMIC	98.543	Loss
AGC_PKC_PKCa_PRKCG_ST	P10636	MAPT	P05129	PRKCG	S721	V728M	728	Missense	distal	7	no	100.732	106.186	EPSD	COSMIC	98.543	Up-regulation
AGC_PKC_PKCa_PRKCG_ST	P10636	MAPT	P05129	PRKCG	S721	V728A	728	Missense	distal	7	no	100.732	107.777	EPSD	COSMIC	98.543	Up-regulation
AGC_PKC_PKCa_PRKCG_ST	P10636	MAPT	P05129	PRKCG	S726	G732S	732	Missense	distal	6	no	107.088	102.756	EPSD	COSMIC	98.543	Down-regulation
AGC_PKC_PKCa_PRKCG_ST	P10636	MAPT	P05129	PRKCG	S726	G732C	732	Missense	distal	6	no	107.088	101.209	EPSD	COSMIC	98.543	Down-regulation
AGC_PKC_PKCa_PRKCG_ST	P10636	MAPT	P05129	PRKCG	S726	R723W	723	Missense	distal	-3	no	107.088	82.697	EPSD	COSMIC	98.543	Loss
AGC_PKC_PKCa_PRKCG_ST	P10636	MAPT	P05129	PRKCG	S726	V728M	728	Missense	proximal	2	no	107.088	78.718	EPSD	COSMIC	98.543	Loss
AGC_PKC_PKCa_PRKCG_ST	P10636	MAPT	P05129	PRKCG	S726	V728A	728	Missense	proximal	2	no	107.088	92.352	EPSD	COSMIC	98.543	Loss
AGC_PKC_PKCa_PRKCG_ST	P98082	DAB2	P05129	PRKCG	S2	E4K	4	Missense	proximal	2	no	101.006	132.958	EPSD	COSMIC	98.543	Up-regulation
AGC_PKC_PKCa_PRKCG_ST	P98082	DAB2	P05129	PRKCG	T7	E4K	4	Missense	distal	-3	no	101.563	112.426	EPSD	COSMIC	98.543	Up-regulation
AGC_PKC_PKCa_PRKCG_ST	P98082	DAB2	P05129	PRKCG	S8	E4K	4	Missense	distal	-4	no	120.522	122.101	EPSD	COSMIC	98.543	Up-regulation
AGC_PKC_PKCa_PRKCG_ST	P98082	DAB2	P05129	PRKCG	S8	D15Y	15	Missense	distal	7	no	120.522	126.605	EPSD	COSMIC	98.543	Up-regulation
AGC_PKC_PKCa_PRKCG_ST	P98082	DAB2	P05129	PRKCG	T10	E4K	4	Missense	distal	-6	no	106.074	109.446	EPSD	COSMIC	98.543	Up-regulation
AGC_PKC_PKCa_PRKCG_ST	P98082	DAB2	P05129	PRKCG	T10	D15Y	15	Missense	distal	5	no	106.074	107.767	EPSD	COSMIC	98.543	Up-regulation
AGC_PKC_PKCa_PRKCG_ST	P98082	DAB2	P05129	PRKCG	S24	K26M	26	Missense	proximal	2	no	142.045	106.881	PhosphoSitePlus	COSMIC	98.543	Down-regulation
AGC_PKC_PKCa_PRKCG_ST	P98082	DAB2	P05129	PRKCG	S24	P23L	23	Missense	proximal	-1	no	142.045	142.539	PhosphoSitePlus	COSMIC	98.543	Up-regulation
AGC_PKC_PKCa_PRKCG_ST	P98082	DAB2	P05129	PRKCG	S24	G31V	31	Missense	distal	7	no	142.045	142.912	PhosphoSitePlus	COSMIC	98.543	Up-regulation
AGC_PKC_PKCa_PRKCG_ST	P98082	DAB2	P05129	PRKCG	S24	A18S	18	Missense	distal	-6	no	142.045	139.214	PhosphoSitePlus	COSMIC	98.543	Down-regulation
AGC_PKC_PKCa_PRKCG_ST	P98082	DAB2	P05129	PRKCG	S249	E252Q	252	Missense	distal	3	no	101.481	91.605	EPSD	COSMIC	98.543	Loss
AGC_PKC_PKCa_PRKCG_ST	P98082	DAB2	P05129	PRKCG	S313	F311L	311	Missense	proximal	-2	no	90.321	99.204	EPSD	COSMIC;CCLE	98.543	Gain
AGC_PKC_PKCa_PRKCG_ST	P98082	DAB2	P05129	PRKCG	S436	G440R	440	Missense	distal	4	no	100.881	106.135	EPSD	COSMIC	98.543	Up-regulation
AGC_PKC_PKCa_PRKCG_ST	P98082	DAB2	P05129	PRKCG	S436	I431M	431	Missense	distal	-5	no	100.881	98.767	EPSD	COSMIC	98.543	Down-regulation
AGC_PKC_PKCa_PRKCG_ST	P98082	DAB2	P05129	PRKCG	S436	G442D	442	Missense	distal	6	no	100.881	97.972	EPSD	COSMIC	98.543	Loss
AGC_PKC_PKCa_PRKCG_ST	P98082	DAB2	P05129	PRKCG	S436	R443W	443	Missense	distal	7	no	100.881	87.035	EPSD	COSMIC	98.543	Loss
AGC_PKC_PKCa_PRKCG_ST	P98082	DAB2	P05129	PRKCG	S436	R443L	443	Missense	distal	7	no	100.881	99.589	EPSD	COSMIC	98.543	Down-regulation
AGC_PKC_PKCa_PRKCG_ST	P98082	DAB2	P05129	PRKCG	S448	R443W	443	Missense	distal	-5	no	93.785	98.789	EPSD	COSMIC	98.543	Gain
AGC_PKC_PKCa_PRKCG_ST	P98082	DAB2	P05129	PRKCG	S471	T473K	473	Missense	proximal	2	no	80.250	98.881	EPSD	COSMIC	98.543	Gain
AGC_PKC_PKCa_PRKCG_ST	P98082	DAB2	P05129	PRKCG	S676	T674A	674	Missense	proximal	-2	no	103.739	96.713	EPSD	COSMIC	98.543	Loss
AGC_PKC_PKCa_PRKCG_ST	P98082	DAB2	P05129	PRKCG	S676	A681V	681	Missense	distal	5	no	103.739	96.432	EPSD	COSMIC	98.543	Loss
AGC_PKC_PKCa_PRKCG_ST	P98082	DAB2	P05129	PRKCG	S688	A681V	681	Missense	distal	-7	no	109.302	107.433	EPSD	COSMIC	98.543	Down-regulation
AGC_PKC_PKCa_PRKCG_ST	P98082	DAB2	P05129	PRKCG	S688	G691D	691	Missense	distal	3	no	109.302	104.414	EPSD	COSMIC	98.543	Down-regulation
AGC_PKC_PKCa_PRKCG_ST	Q03721	KCNC4	P05129	PRKCG	S21	E28K	28	Missense	distal	7	no	135.397	134.373	EPSD;PhosphoSitePlus	COSMIC	98.543	Down-regulation
AGC_PKC_PKCa_PRKCG_ST	Q03721	KCNC4	P05129	PRKCG	T49	T45M	45	Missense	distal	-4	no	109.119	109.060	EPSD	COSMIC	98.543	Down-regulation
AGC_PKC_PKCa_PRKCG_ST	Q03721	KCNC4	P05129	PRKCG	T578	D581H	581	Missense	distal	3	no	118.699	123.747	EPSD	COSMIC	98.543	Up-regulation
AGC_PKC_PKCa_PRKCG_ST	Q03721	KCNC4	P05129	PRKCG	T578	R580Q	580	Missense	proximal	2	no	118.699	88.542	EPSD	COSMIC	98.543	Loss
AGC_PKC_PKCa_PRKCG_ST	P43629	KIR3DL1	P05129	PRKCG	S225	E222K	222	Missense	distal	-3	no	104.033	114.896	EPSD	COSMIC	98.543	Up-regulation
AGC_PKC_PKCa_PRKCG_ST	P43629	KIR3DL1	P05129	PRKCG	S225	P220L	220	Missense	distal	-5	no	104.033	104.022	EPSD	COSMIC	98.543	Down-regulation
AGC_PKC_PKCa_PRKCG_ST	P43629	KIR3DL1	P05129	PRKCG	S415	R413P	413	Missense	proximal	-2	no	129.110	115.500	PhosphoSitePlus	COSMIC	98.543	Down-regulation
AGC_PKC_PKCa_PRKCG_ST	P43629	KIR3DL1	P05129	PRKCG	S415	R409T	409	Missense	distal	-6	no	129.110	127.216	PhosphoSitePlus	COSMIC	98.543	Down-regulation
AGC_PKC_PKCa_PRKCG_ST	P43629	KIR3DL1	P05129	PRKCG	S415	K419E	419	Missense	distal	4	no	129.110	124.627	PhosphoSitePlus	COSMIC	98.543	Down-regulation
AGC_PKC_PKCa_PRKCG_ST	P43629	KIR3DL1	P05129	PRKCG	S415	I411S	411	Missense	distal	-4	no	129.110	132.022	PhosphoSitePlus	COSMIC	98.543	Up-regulation
AGC_PKC_PKCa_PRKCG_ST	P49841	GSK3B	P05129	PRKCG	S2	S9F	9	Missense	distal	7	no	103.176	108.940	EPSD	COSMIC	98.543	Up-regulation
AGC_PKC_PKCa_PRKCG_ST	P49841	GSK3B	P05129	PRKCG	S2	S2P	2	Missense	central	0	yes	103.176	0.000	EPSD	COSMIC	98.543	Loss
AGC_PKC_PKCa_PRKCG_ST	P49841	GSK3B	P05129	PRKCG	T7	S9F	9	Missense	proximal	2	no	116.006	119.499	EPSD	COSMIC	98.543	Up-regulation
AGC_PKC_PKCa_PRKCG_ST	P49841	GSK3B	P05129	PRKCG	T7	S2P	2	Missense	distal	-5	no	116.006	119.263	EPSD	COSMIC	98.543	Up-regulation
AGC_PKC_PKCa_PRKCG_ST	P49841	GSK3B	P05129	PRKCG	T8	S9F	9	Missense	proximal	1	no	103.139	113.836	EPSD	COSMIC	98.543	Up-regulation
AGC_PKC_PKCa_PRKCG_ST	P49841	GSK3B	P05129	PRKCG	T8	S2P	2	Missense	distal	-6	no	103.139	103.838	EPSD	COSMIC	98.543	Up-regulation
AGC_PKC_PKCa_PRKCG_ST	P49841	GSK3B	P05129	PRKCG	S9	S9F	9	Missense	central	0	yes	131.312	0.000	PhosphoSitePlus	COSMIC	98.543	Loss
AGC_PKC_PKCa_PRKCG_ST	P49841	GSK3B	P05129	PRKCG	S9	P16A	16	Missense	distal	7	no	131.312	140.838	PhosphoSitePlus	COSMIC	98.543	Up-regulation
AGC_PKC_PKCa_PRKCG_ST	P49841	GSK3B	P05129	PRKCG	S9	S2P	2	Missense	distal	-7	no	131.312	129.030	PhosphoSitePlus	COSMIC	98.543	Down-regulation
AGC_PKC_PKCa_PRKCG_ST	P49841	GSK3B	P05129	PRKCG	S13	S9F	9	Missense	distal	-4	no	109.051	108.661	EPSD	COSMIC	98.543	Down-regulation
AGC_PKC_PKCa_PRKCG_ST	P49841	GSK3B	P05129	PRKCG	S13	P16A	16	Missense	distal	3	no	109.051	103.861	EPSD	COSMIC	98.543	Down-regulation
AGC_PKC_PKCa_PRKCG_ST	P49841	GSK3B	P05129	PRKCG	S21	S25C	25	Missense	distal	4	no	118.678	110.820	EPSD	COSMIC	98.543	Down-regulation
AGC_PKC_PKCa_PRKCG_ST	P49841	GSK3B	P05129	PRKCG	S21	P16A	16	Missense	distal	-5	no	118.678	117.210	EPSD	COSMIC	98.543	Down-regulation
AGC_PKC_PKCa_PRKCG_ST	P49841	GSK3B	P05129	PRKCG	S21	A22T	22	Missense	proximal	1	no	118.678	119.558	EPSD	COSMIC	98.543	Up-regulation
AGC_PKC_PKCa_PRKCG_ST	P49841	GSK3B	P05129	PRKCG	S25	A22T	22	Missense	distal	-3	no	90.816	98.563	EPSD	COSMIC	98.543	Gain
AGC_PKC_PKCa_PRKCG_ST	P49841	GSK3B	P05129	PRKCG	S35	D31Y	31	Missense	distal	-4	no	104.123	102.628	EPSD	COSMIC	98.543	Down-regulation
AGC_PKC_PKCa_PRKCG_ST	P49841	GSK3B	P05129	PRKCG	S35	D33N	33	Missense	proximal	-2	no	104.123	111.971	EPSD	COSMIC	98.543	Up-regulation
AGC_PKC_PKCa_PRKCG_ST	P49841	GSK3B	P05129	PRKCG	S35	S35R	35	Missense	central	0	yes	104.123	0.000	EPSD	COSMIC	98.543	Loss
AGC_PKC_PKCa_PRKCG_ST	P49841	GSK3B	P05129	PRKCG	S35	V41G	41	Missense	distal	6	no	104.123	106.932	EPSD	COSMIC	98.543	Up-regulation
AGC_PKC_PKCa_PRKCG_ST	P49841	GSK3B	P05129	PRKCG	S35	V37G	37	Missense	proximal	2	no	104.123	93.740	EPSD	COSMIC	98.543	Loss
AGC_PKC_PKCa_PRKCG_ST	P49841	GSK3B	P05129	PRKCG	S35	D33G	33	Missense	proximal	-2	no	104.123	114.563	EPSD	COSMIC;GDSC;CCLE	98.543	Up-regulation
AGC_PKC_PKCa_PRKCG_ST	P49841	GSK3B	P05129	PRKCG	S35	D33H	33	Missense	proximal	-2	no	104.123	120.408	EPSD	COSMIC	98.543	Up-regulation
AGC_PKC_PKCa_PRKCG_ST	P49841	GSK3B	P05129	PRKCG	S66	G63A	63	Missense	distal	-3	no	98.842	93.991	EPSD	COSMIC	98.543	Loss
AGC_PKC_PKCa_PRKCG_ST	P49841	GSK3B	P05129	PRKCG	S66	Y71H	71	Missense	distal	5	no	98.842	100.083	EPSD	COSMIC	98.543	Up-regulation
AGC_PKC_PKCa_PRKCG_ST	P49841	GSK3B	P05129	PRKCG	S66	G65E	65	Missense	proximal	-1	no	98.842	98.559	EPSD	COSMIC;GDSC;CCLE	98.543	Down-regulation
AGC_PKC_PKCa_PRKCG_ST	P49841	GSK3B	P05129	PRKCG	S66	A73T	73	Missense	distal	7	no	98.842	91.250	EPSD	COSMIC	98.543	Loss
AGC_PKC_PKCa_PRKCG_ST	P49841	GSK3B	P05129	PRKCG	S66	A73G	73	Missense	distal	7	no	98.842	90.929	EPSD	COSMIC	98.543	Loss
AGC_PKC_PKCa_PRKCG_ST	Q13507	TRPC3	P05129	PRKCG	S50	E48K	48	Missense	proximal	-2	no	80.742	99.995	EPSD	COSMIC	98.543	Gain
AGC_PKC_PKCa_PRKCG_ST	Q13507	TRPC3	P05129	PRKCG	S295	S293T	293	Missense	proximal	-2	no	101.335	105.983	EPSD	COSMIC	98.543	Up-regulation
AGC_PKC_PKCa_PRKCG_ST	P50281	MMP14	P05129	PRKCG	T567	H565Q	565	Missense	proximal	-2	no	106.586	100.926	PhosphoSitePlus	COSMIC	98.543	Down-regulation
AGC_PKC_PKCa_PRKCG_ST	Q9UBS0	RPS6KB2	P05129	PRKCG	T11	E16K	16	Missense	distal	5	no	88.740	100.684	EPSD	COSMIC	98.543	Gain
AGC_PKC_PKCa_PRKCG_ST	Q9UBS0	RPS6KB2	P05129	PRKCG	S15	E16K	16	Missense	proximal	1	no	122.067	128.600	EPSD	COSMIC	98.543	Up-regulation
AGC_PKC_PKCa_PRKCG_ST	Q9UBS0	RPS6KB2	P05129	PRKCG	S15	G14S	14	Missense	proximal	-1	no	122.067	125.905	EPSD	COSMIC	98.543	Up-regulation
AGC_PKC_PKCa_PRKCG_ST	Q9UBS0	RPS6KB2	P05129	PRKCG	S15	S15G	15	Missense	central	0	yes	122.067	0.000	EPSD	COSMIC	98.543	Loss
AGC_PKC_PKCa_PRKCG_ST	Q9UBS0	RPS6KB2	P05129	PRKCG	S266	A271S	271	Missense	distal	5	no	103.558	103.883	EPSD	COSMIC;GDSC;CCLE	98.543	Up-regulation
AGC_PKC_PKCa_PRKCG_ST	Q9UBS0	RPS6KB2	P05129	PRKCG	S266	A271T	271	Missense	distal	5	no	103.558	105.134	EPSD	COSMIC;GDSC;CCLE	98.543	Up-regulation
AGC_PKC_PKCa_PRKCG_ST	Q9UBS0	RPS6KB2	P05129	PRKCG	S410	R413C	413	Missense	distal	3	no	110.155	97.535	EPSD	COSMIC	98.543	Loss
AGC_PKC_PKCa_PRKCG_ST	Q9UBS0	RPS6KB2	P05129	PRKCG	S410	R413H	413	Missense	distal	3	no	110.155	109.806	EPSD	COSMIC	98.543	Down-regulation
AGC_PKC_PKCa_PRKCG_ST	Q9UBS0	RPS6KB2	P05129	PRKCG	S416	P421S	421	Missense	distal	5	no	98.869	99.338	EPSD	COSMIC	98.543	Up-regulation
AGC_PKC_PKCa_PRKCG_ST	Q9UBS0	RPS6KB2	P05129	PRKCG	S416	R413C	413	Missense	distal	-3	no	98.869	71.296	EPSD	COSMIC	98.543	Loss
AGC_PKC_PKCa_PRKCG_ST	Q9UBS0	RPS6KB2	P05129	PRKCG	S416	R413H	413	Missense	distal	-3	no	98.869	96.110	EPSD	COSMIC	98.543	Loss
AGC_PKC_PKCa_PRKCG_ST	Q9UBS0	RPS6KB2	P05129	PRKCG	S416	P421L	421	Missense	distal	5	no	98.869	97.143	EPSD	COSMIC	98.543	Loss
AGC_PKC_PKCa_PRKCG_ST	Q9UBS0	RPS6KB2	P05129	PRKCG	S436	G432R	432	Missense	distal	-4	no	98.543	99.249	EPSD	COSMIC	98.543	Up-regulation
AGC_PKC_PKCa_PRKCG_ST	Q9UBS0	RPS6KB2	P05129	PRKCG	S436	T443M	443	Missense	distal	7	no	98.543	104.544	EPSD	COSMIC	98.543	Up-regulation
AGC_PKC_PKCa_PRKCG_ST	Q9UBS0	RPS6KB2	P05129	PRKCG	S436	P429S	429	Missense	distal	-7	no	98.543	100.825	EPSD	COSMIC	98.543	Up-regulation
AGC_PKC_PKCa_PRKCG_ST	Q9UBS0	RPS6KB2	P05129	PRKCG	S438	G432R	432	Missense	distal	-6	no	95.351	98.931	EPSD	COSMIC	98.543	Gain
AGC_PKC_PKCa_PRKCG_ST	Q9UBS0	RPS6KB2	P05129	PRKCG	S438	T443M	443	Missense	distal	5	no	95.351	98.729	EPSD	COSMIC	98.543	Gain
AGC_PKC_PKCa_PRKCG_ST	Q9UBS0	RPS6KB2	P05129	PRKCG	S468	S468P	468	Missense	central	0	yes	120.352	0.000	EPSD	COSMIC	98.543	Loss
AGC_PKC_PKCa_PRKCG_ST	Q9UBS0	RPS6KB2	P05129	PRKCG	S468	P463S	463	Missense	distal	-5	no	120.352	117.095	EPSD	COSMIC	98.543	Down-regulation
AGC_PKC_PKCa_PRKCG_ST	Q9UBS0	RPS6KB2	P05129	PRKCG	S468	R475G	475	Missense	distal	7	no	120.352	114.725	EPSD	COSMIC	98.543	Down-regulation
AGC_PKC_PKCa_PRKCG_ST	Q9UBS0	RPS6KB2	P05129	PRKCG	S468	P467H	467	Missense	proximal	-1	no	120.352	119.805	EPSD	COSMIC	98.543	Down-regulation
AGC_PKC_PKCa_PRKCG_ST	Q9UBS0	RPS6KB2	P05129	PRKCG	S468	R465H	465	Missense	distal	-3	no	120.352	117.594	EPSD	COSMIC	98.543	Down-regulation
AGC_PKC_PKCa_PRKCG_ST	Q9UBS0	RPS6KB2	P05129	PRKCG	T470	P463S	463	Missense	distal	-7	no	97.013	99.295	EPSD	COSMIC	98.543	Gain
AGC_PKC_PKCa_PRKCG_ST	Q9UBS0	RPS6KB2	P05129	PRKCG	T470	P467H	467	Missense	distal	-3	no	97.013	106.370	EPSD	COSMIC	98.543	Gain
AGC_PKC_PKCa_PRKCG_ST	Q9UBS0	RPS6KB2	P05129	PRKCG	T470	R465H	465	Missense	distal	-5	no	97.013	99.589	EPSD	COSMIC	98.543	Gain
AGC_PKC_PKCa_PRKCG_ST	Q9UBS0	RPS6KB2	P05129	PRKCG	S473	R479H	479	Missense	distal	6	no	125.993	122.819	PhosphoSitePlus	COSMIC;CCLE	98.543	Down-regulation
AGC_PKC_PKCa_PRKCG_ST	Q9UBS0	RPS6KB2	P05129	PRKCG	S473	S468P	468	Missense	distal	-5	no	125.993	129.251	PhosphoSitePlus	COSMIC	98.543	Up-regulation
AGC_PKC_PKCa_PRKCG_ST	Q9UBS0	RPS6KB2	P05129	PRKCG	S473	P480Q	480	Missense	distal	7	no	125.993	128.993	PhosphoSitePlus	COSMIC	98.543	Up-regulation
AGC_PKC_PKCa_PRKCG_ST	Q9UBS0	RPS6KB2	P05129	PRKCG	S473	R477H	477	Missense	distal	4	no	125.993	120.557	PhosphoSitePlus	COSMIC	98.543	Down-regulation
AGC_PKC_PKCa_PRKCG_ST	Q9UBS0	RPS6KB2	P05129	PRKCG	S473	R475G	475	Missense	proximal	2	no	125.993	104.348	PhosphoSitePlus	COSMIC	98.543	Down-regulation
AGC_PKC_PKCa_PRKCG_ST	Q9UBS0	RPS6KB2	P05129	PRKCG	S473	P467H	467	Missense	distal	-6	no	125.993	127.137	PhosphoSitePlus	COSMIC	98.543	Up-regulation
AGC_PKC_PKCa_PRKCG_ST	Q14155	ARHGEF7	P05129	PRKCG	T13	G15W	15	Missense	proximal	2	no	103.662	94.854	EPSD	COSMIC	98.543	Loss
AGC_PKC_PKCa_PRKCG_ST	Q14155	ARHGEF7	P05129	PRKCG	S19	G15W	15	Missense	distal	-4	no	103.720	101.462	EPSD	COSMIC	98.543	Down-regulation
AGC_PKC_PKCa_PRKCG_ST	Q14155	ARHGEF7	P05129	PRKCG	S19	D26A	26	Missense	distal	7	no	103.720	113.541	EPSD	COSMIC	98.543	Up-regulation
AGC_PKC_PKCa_PRKCG_ST	Q14155	ARHGEF7	P05129	PRKCG	S19	K22T	22	Missense	distal	3	no	103.720	91.951	EPSD	COSMIC;GDSC;CCLE	98.543	Loss
AGC_PKC_PKCa_PRKCG_ST	Q14155	ARHGEF7	P05129	PRKCG	T23	D26A	26	Missense	distal	3	no	122.016	116.864	EPSD	COSMIC	98.543	Down-regulation
AGC_PKC_PKCa_PRKCG_ST	Q14155	ARHGEF7	P05129	PRKCG	T23	K22T	22	Missense	proximal	-1	no	122.016	120.346	EPSD	COSMIC;GDSC;CCLE	98.543	Down-regulation
AGC_PKC_PKCa_PRKCG_ST	Q14155	ARHGEF7	P05129	PRKCG	S147	P146A	146	Missense	proximal	-1	no	97.046	98.585	EPSD	COSMIC;GDSC;CCLE	98.543	Gain
AGC_PKC_PKCa_PRKCG_ST	Q14155	ARHGEF7	P05129	PRKCG	S147	S148F	148	Missense	proximal	1	no	97.046	107.743	EPSD	COSMIC	98.543	Gain
AGC_PKC_PKCa_PRKCG_ST	Q14155	ARHGEF7	P05129	PRKCG	S148	D155G	155	Missense	distal	7	no	97.709	99.618	EPSD	COSMIC	98.543	Gain
AGC_PKC_PKCa_PRKCG_ST	Q14155	ARHGEF7	P05129	PRKCG	S148	P146A	146	Missense	proximal	-2	no	97.709	99.528	EPSD	COSMIC;GDSC;CCLE	98.543	Gain
AGC_PKC_PKCa_PRKCG_ST	Q14155	ARHGEF7	P05129	PRKCG	S148	P146L	146	Missense	proximal	-2	no	97.709	104.842	EPSD	COSMIC	98.543	Gain
AGC_PKC_PKCa_PRKCG_ST	Q14155	ARHGEF7	P05129	PRKCG	S244	E245K	245	Missense	proximal	1	no	99.404	105.937	EPSD	COSMIC	98.543	Up-regulation
AGC_PKC_PKCa_PRKCG_ST	Q14155	ARHGEF7	P05129	PRKCG	S244	V238M	238	Missense	distal	-6	no	99.404	101.012	EPSD	COSMIC	98.543	Up-regulation
AGC_PKC_PKCa_PRKCG_ST	Q14155	ARHGEF7	P05129	PRKCG	T254	L255F	255	Missense	proximal	1	no	111.855	110.933	EPSD	COSMIC	98.543	Down-regulation
AGC_PKC_PKCa_PRKCG_ST	Q14155	ARHGEF7	P05129	PRKCG	T264	A266V	266	Missense	proximal	2	no	85.171	99.907	EPSD	COSMIC	98.543	Gain
AGC_PKC_PKCa_PRKCG_ST	Q14155	ARHGEF7	P05129	PRKCG	S295	R299Q	299	Missense	distal	4	no	100.873	100.054	EPSD	COSMIC	98.543	Down-regulation
AGC_PKC_PKCa_PRKCG_ST	Q14155	ARHGEF7	P05129	PRKCG	S518	S518C	518	Missense	central	0	yes	122.299	0.000	PhosphoSitePlus;EPSD	COSMIC	98.543	Loss
AGC_PKC_PKCa_PRKCG_ST	Q14155	ARHGEF7	P05129	PRKCG	S518	L511F	511	Missense	distal	-7	no	122.299	122.756	PhosphoSitePlus;EPSD	COSMIC	98.543	Up-regulation
AGC_PKC_PKCa_PRKCG_ST	Q14155	ARHGEF7	P05129	PRKCG	S518	S512F	512	Missense	distal	-6	no	122.299	125.132	PhosphoSitePlus;EPSD	COSMIC	98.543	Up-regulation
AGC_PKC_PKCa_PRKCG_ST	Q14155	ARHGEF7	P05129	PRKCG	S581	T577M	577	Missense	distal	-4	no	110.016	109.957	EPSD	COSMIC;GDSC	98.543	Down-regulation
AGC_PKC_PKCa_PRKCG_ST	Q14155	ARHGEF7	P05129	PRKCG	S581	I587M	587	Missense	distal	6	no	110.016	110.942	EPSD	COSMIC	98.543	Up-regulation
AGC_PKC_PKCa_PRKCG_ST	Q14155	ARHGEF7	P05129	PRKCG	S581	S581P	581	Missense	central	0	yes	110.016	0.000	EPSD	COSMIC	98.543	Loss
AGC_PKC_PKCa_PRKCG_ST	Q14155	ARHGEF7	P05129	PRKCG	S605	S611F	611	Missense	distal	6	no	104.992	107.885	EPSD	COSMIC	98.543	Up-regulation
AGC_PKC_PKCa_PRKCG_ST	Q14155	ARHGEF7	P05129	PRKCG	S605	P604S	604	Missense	proximal	-1	no	104.992	110.057	EPSD	COSMIC	98.543	Up-regulation
AGC_PKC_PKCa_PRKCG_ST	Q14155	ARHGEF7	P05129	PRKCG	S605	H608Q	608	Missense	distal	3	no	104.992	96.146	EPSD	COSMIC	98.543	Loss
AGC_PKC_PKCa_PRKCG_ST	Q14155	ARHGEF7	P05129	PRKCG	T679	K686T	686	Missense	distal	7	no	105.583	100.043	EPSD	COSMIC	98.543	Down-regulation
AGC_PKC_PKCa_PRKCG_ST	Q14155	ARHGEF7	P05129	PRKCG	S694	E696K	696	Missense	proximal	2	no	93.443	125.395	EPSD	COSMIC	98.543	Gain
AGC_PKC_PKCa_PRKCG_ST	Q14155	ARHGEF7	P05129	PRKCG	S700	S703R	703	Missense	distal	3	no	88.005	100.370	EPSD	COSMIC	98.543	Gain
AGC_PKC_PKCa_PRKCG_ST	Q14155	ARHGEF7	P05129	PRKCG	S723	A724S	724	Missense	proximal	1	no	99.724	97.492	EPSD	COSMIC	98.543	Loss
AGC_PKC_PKCa_PRKCG_ST	Q14155	ARHGEF7	P05129	PRKCG	S761	S755F	755	Missense	distal	-6	no	124.385	127.219	EPSD;PhosphoSitePlus	COSMIC	98.543	Up-regulation
AGC_PKC_PKCa_PRKCG_ST	Q14155	ARHGEF7	P05129	PRKCG	S761	R764H	764	Missense	distal	3	no	124.385	124.036	EPSD;PhosphoSitePlus	COSMIC	98.543	Down-regulation
AGC_PKC_PKCa_PRKCG_ST	Q14155	ARHGEF7	P05129	PRKCG	S761	R759C	759	Missense	proximal	-2	no	124.385	114.192	EPSD;PhosphoSitePlus	COSMIC	98.543	Down-regulation
AGC_PKC_PKCa_PRKCG_ST	Q14155	ARHGEF7	P05129	PRKCG	S761	S768F	768	Missense	distal	7	no	124.385	130.149	EPSD;PhosphoSitePlus	COSMIC	98.543	Up-regulation
AGC_PKC_PKCa_PRKCG_ST	P25098	GRK2	P05129	PRKCG	S29	P24L	24	Missense	distal	-5	no	123.296	123.286	PhosphoSitePlus	COSMIC	98.543	Down-regulation
AGC_PKC_PKCa_PRKCG_ST	P25098	GRK2	P05129	PRKCG	S29	K30R	30	Missense	proximal	1	no	123.296	120.381	PhosphoSitePlus	COSMIC	98.543	Down-regulation
AGC_PKC_PKCa_PRKCG_ST	P25098	GRK2	P05129	PRKCG	T213	A218T	218	Missense	distal	5	no	104.694	106.270	EPSD	COSMIC	98.543	Up-regulation
AGC_PKC_PKCa_PRKCG_ST	P25098	GRK2	P05129	PRKCG	T213	M219I	219	Missense	distal	6	no	104.694	103.768	EPSD	COSMIC	98.543	Down-regulation
AGC_PKC_PKCa_PRKCG_ST	P25098	GRK2	P05129	PRKCG	T213	R209Q	209	Missense	distal	-4	no	104.694	102.711	EPSD	COSMIC	98.543	Down-regulation
AGC_PKC_PKCa_PRKCG_ST	P21730	C5AR1	P05129	PRKCG	S327	E331K	331	Missense	distal	4	no	106.879	111.362	EPSD	COSMIC	98.543	Up-regulation
AGC_PKC_PKCa_PRKCG_ST	P21730	C5AR1	P05129	PRKCG	S334	E331K	331	Missense	distal	-3	no	102.791	113.654	PhosphoSitePlus	COSMIC	98.543	Up-regulation
AGC_PKC_PKCa_PRKCG_ST	P21730	C5AR1	P05129	PRKCG	S334	T336M	336	Missense	proximal	2	no	102.791	86.259	PhosphoSitePlus	COSMIC	98.543	Loss
AGC_PKC_PKCa_PRKCG_ST	Q7Z2E3	APTX	P05129	PRKCG	S26	Q29R	29	Missense	distal	3	no	95.997	105.191	EPSD	COSMIC	98.543	Gain
AGC_PKC_PKCa_PRKCG_ST	Q7Z2E3	APTX	P05129	PRKCG	T125	N120S	120	Missense	distal	-5	no	121.989	120.365	PhosphoSitePlus	COSMIC	98.543	Down-regulation
AGC_PKC_PKCa_PRKCG_ST	Q7Z2E3	APTX	P05129	PRKCG	S132	S137F	137	Missense	distal	5	no	98.842	101.803	EPSD	COSMIC	98.543	Up-regulation
AGC_PKC_PKCa_PRKCG_ST	Q7Z2E3	APTX	P05129	PRKCG	S132	N134S	134	Missense	proximal	2	no	98.842	92.157	EPSD	COSMIC	98.543	Loss
AGC_PKC_PKCa_PRKCG_ST	Q7Z2E3	APTX	P05129	PRKCG	S177	P172R	172	Missense	distal	-5	no	98.621	95.801	EPSD	COSMIC	98.543	Loss
AGC_PKC_PKCa_PRKCG_ST	Q7Z2E3	APTX	P05129	PRKCG	S177	A171G	171	Missense	distal	-6	no	98.621	95.959	EPSD	COSMIC	98.543	Loss
AGC_PKC_PKCa_PRKCG_ST	Q7Z2E3	APTX	P05129	PRKCG	S177	S177F	177	Missense	central	0	yes	98.621	0.000	EPSD	COSMIC	98.543	Loss
AGC_PKC_PKCa_PRKCG_ST	P06127	CD5	P05129	PRKCG	S309	S309L	309	Missense	central	0	yes	101.124	0.000	EPSD	COSMIC	98.543	Loss
AGC_PKC_PKCa_PRKCG_ST	P06127	CD5	P05129	PRKCG	T434	R431H	431	Missense	distal	-3	no	123.839	121.080	PhosphoSitePlus;EPSD	COSMIC	98.543	Down-regulation
AGC_PKC_PKCa_PRKCG_ST	P06127	CD5	P05129	PRKCG	T434	T434M	434	Missense	central	0	yes	123.839	0.000	PhosphoSitePlus;EPSD	COSMIC	98.543	Loss
AGC_PKC_PKCa_PRKCG_ST	P06127	CD5	P05129	PRKCG	T436	R431H	431	Missense	distal	-5	no	119.055	121.631	EPSD;PhosphoSitePlus	COSMIC	98.543	Up-regulation
AGC_PKC_PKCa_PRKCG_ST	P06127	CD5	P05129	PRKCG	T436	T434M	434	Missense	proximal	-2	no	119.055	118.673	EPSD;PhosphoSitePlus	COSMIC	98.543	Down-regulation
AGC_PKC_PKCa_PRKCG_ST	P28329	CHAT	P05129	PRKCG	S244	L248V	248	Missense	distal	4	no	119.660	116.163	EPSD	COSMIC	98.543	Down-regulation
AGC_PKC_PKCa_PRKCG_ST	P28329	CHAT	P05129	PRKCG	S244	L248P	248	Missense	distal	4	no	119.660	121.273	EPSD	COSMIC	98.543	Up-regulation
AGC_PKC_PKCa_PRKCG_ST	P28329	CHAT	P05129	PRKCG	S244	S240F	240	Missense	distal	-4	no	119.660	119.269	EPSD	COSMIC	98.543	Down-regulation
AGC_PKC_PKCa_PRKCG_ST	P28329	CHAT	P05129	PRKCG	S244	L243F	243	Missense	proximal	-1	no	119.660	123.820	EPSD	COSMIC	98.543	Up-regulation
AGC_PKC_PKCa_PRKCG_ST	P28329	CHAT	P05129	PRKCG	S244	D250N	250	Missense	distal	6	no	119.660	124.037	EPSD	COSMIC	98.543	Up-regulation
AGC_PKC_PKCa_PRKCG_ST	P28329	CHAT	P05129	PRKCG	S244	S237N	237	Missense	distal	-7	no	119.660	118.206	EPSD	COSMIC	98.543	Down-regulation
AGC_PKC_PKCa_PRKCG_ST	P28329	CHAT	P05129	PRKCG	T373	R375Q	375	Missense	proximal	2	no	125.078	94.921	EPSD	COSMIC	98.543	Loss
AGC_PKC_PKCa_PRKCG_ST	P28329	CHAT	P05129	PRKCG	T373	K370R	370	Missense	distal	-3	no	125.078	126.644	EPSD	COSMIC	98.543	Up-regulation
AGC_PKC_PKCa_PRKCG_ST	P28329	CHAT	P05129	PRKCG	T373	T366M	366	Missense	distal	-7	no	125.078	122.759	EPSD	COSMIC	98.543	Down-regulation
AGC_PKC_PKCa_PRKCG_ST	P28329	CHAT	P05129	PRKCG	T373	V369M	369	Missense	distal	-4	no	125.078	126.304	EPSD	COSMIC	98.543	Up-regulation
AGC_PKC_PKCa_PRKCG_ST	P28329	CHAT	P05129	PRKCG	T373	D376G	376	Missense	distal	3	no	125.078	129.966	EPSD	COSMIC	98.543	Up-regulation
AGC_PKC_PKCa_PRKCG_ST	P28329	CHAT	P05129	PRKCG	S464	R466Q	466	Missense	proximal	2	no	131.934	101.777	EPSD	COSMIC	98.543	Down-regulation
AGC_PKC_PKCa_PRKCG_ST	P28329	CHAT	P05129	PRKCG	S464	R466L	466	Missense	proximal	2	no	131.934	113.372	EPSD	COSMIC	98.543	Down-regulation
AGC_PKC_PKCa_PRKCG_ST	P28329	CHAT	P05129	PRKCG	S465	R466Q	466	Missense	proximal	1	no	123.224	120.502	EPSD	COSMIC	98.543	Down-regulation
AGC_PKC_PKCa_PRKCG_ST	P28329	CHAT	P05129	PRKCG	S465	R466L	466	Missense	proximal	1	no	123.224	125.906	EPSD	COSMIC	98.543	Up-regulation
AGC_PKC_PKCa_PRKCG_ST	P28329	CHAT	P05129	PRKCG	S558	E555K	555	Missense	distal	-3	no	134.661	145.524	EPSD	COSMIC	98.543	Up-regulation
AGC_PKC_PKCa_PRKCG_ST	P28329	CHAT	P05129	PRKCG	S558	A557T	557	Missense	proximal	-1	no	134.661	134.303	EPSD	COSMIC;GDSC	98.543	Down-regulation
AGC_PKC_PKCa_PRKCG_ST	P28329	CHAT	P05129	PRKCG	S558	R560C	560	Missense	proximal	2	no	134.661	87.761	EPSD	COSMIC	98.543	Loss
AGC_PKC_PKCa_PRKCG_ST	P28329	CHAT	P05129	PRKCG	S558	V551A	551	Missense	distal	-7	no	134.661	136.529	EPSD	COSMIC	98.543	Up-regulation
AGC_PKC_PKCa_PRKCG_ST	P28329	CHAT	P05129	PRKCG	S594	K588M	588	Missense	distal	-6	no	127.395	124.399	EPSD	COSMIC	98.543	Down-regulation
AGC_PKC_PKCa_PRKCG_ST	P28329	CHAT	P05129	PRKCG	S594	L599F	599	Missense	distal	5	no	127.395	132.550	EPSD	COSMIC	98.543	Up-regulation
AGC_PKC_PKCa_PRKCG_ST	P28329	CHAT	P05129	PRKCG	S594	E595K	595	Missense	proximal	1	no	127.395	133.928	EPSD	COSMIC	98.543	Up-regulation
AGC_PKC_PKCa_PRKCG_ST	P28329	CHAT	P05129	PRKCG	S730	E729D	729	Missense	proximal	-1	no	94.821	99.293	EPSD	COSMIC	98.543	Gain
AGC_PKC_PKCa_PRKCG_ST	P08138	NGFR	P05129	PRKCG	S277	Q280K	280	Missense	distal	3	no	131.284	141.132	PhosphoSitePlus	COSMIC	98.543	Up-regulation
AGC_PKC_PKCa_PRKCG_ST	P49840	GSK3A	P05129	PRKCG	S97	V104I	104	Missense	distal	7	no	113.865	109.768	EPSD	COSMIC;GDSC;CCLE	98.543	Down-regulation
AGC_PKC_PKCa_PRKCG_ST	P49840	GSK3A	P05129	PRKCG	S129	G128S	128	Missense	proximal	-1	no	94.825	98.663	EPSD	COSMIC	98.543	Gain
AGC_PKC_PKCa_PRKCG_ST	P49840	GSK3A	P05129	PRKCG	S129	G131V	131	Missense	proximal	2	no	94.825	105.208	EPSD	COSMIC	98.543	Gain
TK_PDGFR_FLT3_Y	P36888	FLT3	P36888	FLT3	Y572	Y572C	572	Missense	central	0	yes	1.348	0.000	EPSD	COSMIC	0.779	Loss
TK_PDGFR_FLT3_Y	P36888	FLT3	P36888	FLT3	Y572	M578I	578	Missense	distal	6	no	1.348	1.374	EPSD	COSMIC	0.779	Up-regulation
TK_PDGFR_FLT3_Y	P36888	FLT3	P36888	FLT3	Y572	M578T	578	Missense	distal	6	no	1.348	1.358	EPSD	COSMIC	0.779	Up-regulation
TK_PDGFR_FLT3_Y	P36888	FLT3	P36888	FLT3	Y572	V579I	579	Missense	distal	7	no	1.348	1.370	EPSD	COSMIC	0.779	Up-regulation
TK_PDGFR_FLT3_Y	P36888	FLT3	P36888	FLT3	Y572	K567R	567	Missense	distal	-5	no	1.348	1.341	EPSD	COSMIC	0.779	Down-regulation
TK_PDGFR_FLT3_Y	P36888	FLT3	P36888	FLT3	Y572	Y566N	566	Missense	distal	-6	no	1.348	1.393	EPSD	COSMIC	0.779	Up-regulation
TK_PDGFR_FLT3_Y	P36888	FLT3	P36888	FLT3	Y572	Q577H	577	Missense	distal	5	no	1.348	1.343	EPSD	COSMIC	0.779	Down-regulation
TK_PDGFR_FLT3_Y	P36888	FLT3	P36888	FLT3	Y572	S574N	574	Missense	proximal	2	no	1.348	1.368	EPSD	COSMIC	0.779	Up-regulation
TK_PDGFR_FLT3_Y	P36888	FLT3	P36888	FLT3	Y572	E573G	573	Missense	proximal	1	no	1.348	1.273	EPSD	COSMIC	0.779	Down-regulation
TK_PDGFR_FLT3_Y	P36888	FLT3	P36888	FLT3	Y572	L576R	576	Missense	distal	4	no	1.348	1.279	EPSD	COSMIC	0.779	Down-regulation
TK_PDGFR_FLT3_Y	P36888	FLT3	P36888	FLT3	Y572	Q575E	575	Missense	distal	3	no	1.348	1.328	EPSD	COSMIC	0.779	Down-regulation
TK_PDGFR_FLT3_Y	P36888	FLT3	P36888	FLT3	Y572	Q575P	575	Missense	distal	3	no	1.348	1.346	EPSD	COSMIC	0.779	Down-regulation
TK_PDGFR_FLT3_Y	P36888	FLT3	P36888	FLT3	Y572	S574G	574	Missense	proximal	2	no	1.348	1.376	EPSD	COSMIC	0.779	Up-regulation
TK_PDGFR_FLT3_Y	P36888	FLT3	P36888	FLT3	Y572	V579E	579	Missense	distal	7	no	1.348	1.339	EPSD	COSMIC	0.779	Down-regulation
TK_PDGFR_FLT3_Y	P36888	FLT3	P36888	FLT3	Y572	F570C	570	Missense	proximal	-2	no	1.348	1.343	EPSD	COSMIC	0.779	Down-regulation
TK_PDGFR_FLT3_Y	P36888	FLT3	P36888	FLT3	Y572	V579L	579	Missense	distal	7	no	1.348	1.429	EPSD	COSMIC	0.779	Up-regulation
TK_PDGFR_FLT3_Y	P36888	FLT3	P36888	FLT3	Y572	E573K	573	Missense	proximal	1	no	1.348	1.304	EPSD	COSMIC	0.779	Down-regulation
TK_PDGFR_FLT3_Y	P36888	FLT3	P36888	FLT3	Y572	L576Q	576	Missense	distal	4	no	1.348	1.206	EPSD	COSMIC	0.779	Down-regulation
TK_PDGFR_FLT3_Y	P36888	FLT3	P36888	FLT3	Y572	V579A	579	Missense	distal	7	no	1.348	1.364	EPSD	COSMIC	0.779	Up-regulation
TK_PDGFR_FLT3_Y	P36888	FLT3	P36888	FLT3	Y589	F594V	594	Missense	distal	5	no	1.059	1.066	EPSD;PhosphoSitePlus	COSMIC	0.779	Up-regulation
TK_PDGFR_FLT3_Y	P36888	FLT3	P36888	FLT3	Y589	Y589D	589	Missense	central	0	yes	1.059	0.000	EPSD;PhosphoSitePlus	COSMIC	0.779	Loss
TK_PDGFR_FLT3_Y	P36888	FLT3	P36888	FLT3	Y589	V592A	592	Missense	distal	3	no	1.059	1.048	EPSD;PhosphoSitePlus	COSMIC;GDSC;CCLE	0.779	Down-regulation
TK_PDGFR_FLT3_Y	P36888	FLT3	P36888	FLT3	Y589	F594L	594	Missense	distal	5	no	1.059	1.042	EPSD;PhosphoSitePlus	COSMIC	0.779	Down-regulation
TK_PDGFR_FLT3_Y	P36888	FLT3	P36888	FLT3	Y589	E588K	588	Missense	proximal	-1	no	1.059	1.075	EPSD;PhosphoSitePlus	COSMIC	0.779	Up-regulation
TK_PDGFR_FLT3_Y	P36888	FLT3	P36888	FLT3	Y589	F594I	594	Missense	distal	5	no	1.059	1.056	EPSD;PhosphoSitePlus	COSMIC	0.779	Down-regulation
TK_PDGFR_FLT3_Y	P36888	FLT3	P36888	FLT3	Y589	D586E	586	Missense	distal	-3	no	1.059	1.114	EPSD;PhosphoSitePlus	COSMIC	0.779	Up-regulation
TK_PDGFR_FLT3_Y	P36888	FLT3	P36888	FLT3	Y589	E588V	588	Missense	proximal	-1	no	1.059	1.063	EPSD;PhosphoSitePlus	COSMIC	0.779	Up-regulation
TK_PDGFR_FLT3_Y	P36888	FLT3	P36888	FLT3	Y589	V592D	592	Missense	distal	3	no	1.059	1.071	EPSD;PhosphoSitePlus	COSMIC	0.779	Up-regulation
TK_PDGFR_FLT3_Y	P36888	FLT3	P36888	FLT3	Y589	E588Q	588	Missense	proximal	-1	no	1.059	1.066	EPSD;PhosphoSitePlus	COSMIC	0.779	Up-regulation
TK_PDGFR_FLT3_Y	P36888	FLT3	P36888	FLT3	Y589	D593N	593	Missense	distal	4	no	1.059	0.973	EPSD;PhosphoSitePlus	COSMIC	0.779	Down-regulation
TK_PDGFR_FLT3_Y	P36888	FLT3	P36888	FLT3	Y589	D593V	593	Missense	distal	4	no	1.059	0.971	EPSD;PhosphoSitePlus	COSMIC	0.779	Down-regulation
TK_PDGFR_FLT3_Y	P36888	FLT3	P36888	FLT3	Y589	Y591C	591	Missense	proximal	2	no	1.059	1.062	EPSD;PhosphoSitePlus	COSMIC	0.779	Up-regulation
TK_PDGFR_FLT3_Y	P36888	FLT3	P36888	FLT3	Y589	T582A	582	Missense	distal	-7	no	1.059	1.071	EPSD;PhosphoSitePlus	COSMIC	0.779	Up-regulation
TK_PDGFR_FLT3_Y	P36888	FLT3	P36888	FLT3	Y589	F590L	590	Missense	proximal	1	no	1.059	1.009	EPSD;PhosphoSitePlus	COSMIC	0.779	Down-regulation
TK_PDGFR_FLT3_Y	P36888	FLT3	P36888	FLT3	Y589	Y591H	591	Missense	proximal	2	no	1.059	1.046	EPSD;PhosphoSitePlus	COSMIC	0.779	Down-regulation
TK_PDGFR_FLT3_Y	P36888	FLT3	P36888	FLT3	Y589	F594S	594	Missense	distal	5	no	1.059	1.065	EPSD;PhosphoSitePlus	COSMIC	0.779	Up-regulation
TK_PDGFR_FLT3_Y	P36888	FLT3	P36888	FLT3	Y589	Y591D	591	Missense	proximal	2	no	1.059	1.072	EPSD;PhosphoSitePlus	COSMIC	0.779	Up-regulation
TK_PDGFR_FLT3_Y	P36888	FLT3	P36888	FLT3	Y589	S584Y	584	Missense	distal	-5	no	1.059	1.031	EPSD;PhosphoSitePlus	COSMIC	0.779	Down-regulation
TK_PDGFR_FLT3_Y	P36888	FLT3	P36888	FLT3	Y589	V592G	592	Missense	distal	3	no	1.059	1.087	EPSD;PhosphoSitePlus	COSMIC	0.779	Up-regulation
TK_PDGFR_FLT3_Y	P36888	FLT3	P36888	FLT3	Y591	F594V	594	Missense	distal	3	no	1.561	1.570	EPSD;PhosphoSitePlus	COSMIC	0.779	Up-regulation
TK_PDGFR_FLT3_Y	P36888	FLT3	P36888	FLT3	Y591	Y589D	589	Missense	proximal	-2	no	1.561	1.536	EPSD;PhosphoSitePlus	COSMIC	0.779	Down-regulation
TK_PDGFR_FLT3_Y	P36888	FLT3	P36888	FLT3	Y591	E598K	598	Missense	distal	7	no	1.561	1.623	EPSD;PhosphoSitePlus	COSMIC	0.779	Up-regulation
TK_PDGFR_FLT3_Y	P36888	FLT3	P36888	FLT3	Y591	V592A	592	Missense	proximal	1	no	1.561	1.549	EPSD;PhosphoSitePlus	COSMIC;GDSC;CCLE	0.779	Down-regulation
TK_PDGFR_FLT3_Y	P36888	FLT3	P36888	FLT3	Y591	F594L	594	Missense	distal	3	no	1.561	1.596	EPSD;PhosphoSitePlus	COSMIC	0.779	Up-regulation
TK_PDGFR_FLT3_Y	P36888	FLT3	P36888	FLT3	Y591	E588K	588	Missense	distal	-3	no	1.561	1.472	EPSD;PhosphoSitePlus	COSMIC	0.779	Down-regulation
TK_PDGFR_FLT3_Y	P36888	FLT3	P36888	FLT3	Y591	F594I	594	Missense	distal	3	no	1.561	1.564	EPSD;PhosphoSitePlus	COSMIC	0.779	Up-regulation
TK_PDGFR_FLT3_Y	P36888	FLT3	P36888	FLT3	Y591	D586E	586	Missense	distal	-5	no	1.561	1.601	EPSD;PhosphoSitePlus	COSMIC	0.779	Up-regulation
TK_PDGFR_FLT3_Y	P36888	FLT3	P36888	FLT3	Y591	E588V	588	Missense	distal	-3	no	1.561	1.536	EPSD;PhosphoSitePlus	COSMIC	0.779	Down-regulation
TK_PDGFR_FLT3_Y	P36888	FLT3	P36888	FLT3	Y591	V592D	592	Missense	proximal	1	no	1.561	1.530	EPSD;PhosphoSitePlus	COSMIC	0.779	Down-regulation
TK_PDGFR_FLT3_Y	P36888	FLT3	P36888	FLT3	Y591	E588Q	588	Missense	distal	-3	no	1.561	1.511	EPSD;PhosphoSitePlus	COSMIC	0.779	Down-regulation
TK_PDGFR_FLT3_Y	P36888	FLT3	P36888	FLT3	Y591	D593N	593	Missense	proximal	2	no	1.561	1.559	EPSD;PhosphoSitePlus	COSMIC	0.779	Down-regulation
TK_PDGFR_FLT3_Y	P36888	FLT3	P36888	FLT3	Y591	D593V	593	Missense	proximal	2	no	1.561	1.545	EPSD;PhosphoSitePlus	COSMIC	0.779	Down-regulation
TK_PDGFR_FLT3_Y	P36888	FLT3	P36888	FLT3	Y591	Y591C	591	Missense	central	0	yes	1.561	0.000	EPSD;PhosphoSitePlus	COSMIC	0.779	Loss
TK_PDGFR_FLT3_Y	P36888	FLT3	P36888	FLT3	Y591	E598G	598	Missense	distal	7	no	1.561	1.651	EPSD;PhosphoSitePlus	COSMIC	0.779	Up-regulation
TK_PDGFR_FLT3_Y	P36888	FLT3	P36888	FLT3	Y591	F590L	590	Missense	proximal	-1	no	1.561	1.576	EPSD;PhosphoSitePlus	COSMIC	0.779	Up-regulation
TK_PDGFR_FLT3_Y	P36888	FLT3	P36888	FLT3	Y591	Y591H	591	Missense	central	0	yes	1.561	0.000	EPSD;PhosphoSitePlus	COSMIC	0.779	Loss
TK_PDGFR_FLT3_Y	P36888	FLT3	P36888	FLT3	Y591	F594S	594	Missense	distal	3	no	1.561	1.572	EPSD;PhosphoSitePlus	COSMIC	0.779	Up-regulation
TK_PDGFR_FLT3_Y	P36888	FLT3	P36888	FLT3	Y591	Y591D	591	Missense	central	0	yes	1.561	0.000	EPSD;PhosphoSitePlus	COSMIC	0.779	Loss
TK_PDGFR_FLT3_Y	P36888	FLT3	P36888	FLT3	Y591	Y597F	597	Missense	distal	6	no	1.561	1.601	EPSD;PhosphoSitePlus	COSMIC	0.779	Up-regulation
TK_PDGFR_FLT3_Y	P36888	FLT3	P36888	FLT3	Y591	E598D	598	Missense	distal	7	no	1.561	1.614	EPSD;PhosphoSitePlus	COSMIC	0.779	Up-regulation
TK_PDGFR_FLT3_Y	P36888	FLT3	P36888	FLT3	Y591	S584Y	584	Missense	distal	-7	no	1.561	1.564	EPSD;PhosphoSitePlus	COSMIC	0.779	Up-regulation
TK_PDGFR_FLT3_Y	P36888	FLT3	P36888	FLT3	Y591	V592G	592	Missense	proximal	1	no	1.561	1.499	EPSD;PhosphoSitePlus	COSMIC	0.779	Down-regulation
TK_PDGFR_FLT3_Y	P36888	FLT3	P36888	FLT3	Y597	Y599C	599	Missense	proximal	2	no	1.311	1.314	EPSD	COSMIC	0.779	Up-regulation
TK_PDGFR_FLT3_Y	P36888	FLT3	P36888	FLT3	Y597	F594V	594	Missense	distal	-3	no	1.311	1.318	EPSD	COSMIC	0.779	Up-regulation
TK_PDGFR_FLT3_Y	P36888	FLT3	P36888	FLT3	Y597	E598K	598	Missense	proximal	1	no	1.311	1.267	EPSD	COSMIC	0.779	Down-regulation
TK_PDGFR_FLT3_Y	P36888	FLT3	P36888	FLT3	Y597	V592A	592	Missense	distal	-5	no	1.311	1.326	EPSD	COSMIC;GDSC;CCLE	0.779	Up-regulation
TK_PDGFR_FLT3_Y	P36888	FLT3	P36888	FLT3	Y597	F594L	594	Missense	distal	-3	no	1.311	1.220	EPSD	COSMIC	0.779	Down-regulation
TK_PDGFR_FLT3_Y	P36888	FLT3	P36888	FLT3	Y597	F594I	594	Missense	distal	-3	no	1.311	1.257	EPSD	COSMIC	0.779	Down-regulation
TK_PDGFR_FLT3_Y	P36888	FLT3	P36888	FLT3	Y597	V592D	592	Missense	distal	-5	no	1.311	1.295	EPSD	COSMIC	0.779	Down-regulation
TK_PDGFR_FLT3_Y	P36888	FLT3	P36888	FLT3	Y597	Y599F	599	Missense	proximal	2	no	1.311	1.316	EPSD	COSMIC	0.779	Up-regulation
TK_PDGFR_FLT3_Y	P36888	FLT3	P36888	FLT3	Y597	L601I	601	Missense	distal	4	no	1.311	1.122	EPSD	COSMIC	0.779	Down-regulation
TK_PDGFR_FLT3_Y	P36888	FLT3	P36888	FLT3	Y597	D593N	593	Missense	distal	-4	no	1.311	1.367	EPSD	COSMIC	0.779	Up-regulation
TK_PDGFR_FLT3_Y	P36888	FLT3	P36888	FLT3	Y597	D593V	593	Missense	distal	-4	no	1.311	1.343	EPSD	COSMIC	0.779	Up-regulation
TK_PDGFR_FLT3_Y	P36888	FLT3	P36888	FLT3	Y597	Y591C	591	Missense	distal	-6	no	1.311	1.329	EPSD	COSMIC	0.779	Up-regulation
TK_PDGFR_FLT3_Y	P36888	FLT3	P36888	FLT3	Y597	W603L	603	Missense	distal	6	no	1.311	1.299	EPSD	COSMIC	0.779	Down-regulation
TK_PDGFR_FLT3_Y	P36888	FLT3	P36888	FLT3	Y597	E598G	598	Missense	proximal	1	no	1.311	1.236	EPSD	COSMIC	0.779	Down-regulation
TK_PDGFR_FLT3_Y	P36888	FLT3	P36888	FLT3	Y597	F590L	590	Missense	distal	-7	no	1.311	1.326	EPSD	COSMIC	0.779	Up-regulation
TK_PDGFR_FLT3_Y	P36888	FLT3	P36888	FLT3	Y597	Y591H	591	Missense	distal	-6	no	1.311	1.245	EPSD	COSMIC	0.779	Down-regulation
TK_PDGFR_FLT3_Y	P36888	FLT3	P36888	FLT3	Y597	L601F	601	Missense	distal	4	no	1.311	1.019	EPSD	COSMIC	0.779	Down-regulation
TK_PDGFR_FLT3_Y	P36888	FLT3	P36888	FLT3	Y597	F594S	594	Missense	distal	-3	no	1.311	1.260	EPSD	COSMIC	0.779	Down-regulation
TK_PDGFR_FLT3_Y	P36888	FLT3	P36888	FLT3	Y597	K602I	602	Missense	distal	5	no	1.311	1.307	EPSD	COSMIC	0.779	Down-regulation
TK_PDGFR_FLT3_Y	P36888	FLT3	P36888	FLT3	Y597	Y591D	591	Missense	distal	-6	no	1.311	1.367	EPSD	COSMIC	0.779	Up-regulation
TK_PDGFR_FLT3_Y	P36888	FLT3	P36888	FLT3	Y597	Y597F	597	Missense	central	0	yes	1.311	0.000	EPSD	COSMIC	0.779	Loss
TK_PDGFR_FLT3_Y	P36888	FLT3	P36888	FLT3	Y597	E598D	598	Missense	proximal	1	no	1.311	1.268	EPSD	COSMIC	0.779	Down-regulation
TK_PDGFR_FLT3_Y	P36888	FLT3	P36888	FLT3	Y597	V592G	592	Missense	distal	-5	no	1.311	1.246	EPSD	COSMIC	0.779	Down-regulation
TK_PDGFR_FLT3_Y	P36888	FLT3	P36888	FLT3	Y599	Y599C	599	Missense	central	0	yes	1.199	0.000	EPSD;PhosphoSitePlus	COSMIC	0.779	Loss
TK_PDGFR_FLT3_Y	P36888	FLT3	P36888	FLT3	Y599	F594V	594	Missense	distal	-5	no	1.199	1.191	EPSD;PhosphoSitePlus	COSMIC	0.779	Down-regulation
TK_PDGFR_FLT3_Y	P36888	FLT3	P36888	FLT3	Y599	E598K	598	Missense	proximal	-1	no	1.199	1.214	EPSD;PhosphoSitePlus	COSMIC	0.779	Up-regulation
TK_PDGFR_FLT3_Y	P36888	FLT3	P36888	FLT3	Y599	V592A	592	Missense	distal	-7	no	1.199	1.206	EPSD;PhosphoSitePlus	COSMIC;GDSC;CCLE	0.779	Up-regulation
TK_PDGFR_FLT3_Y	P36888	FLT3	P36888	FLT3	Y599	F594L	594	Missense	distal	-5	no	1.199	1.109	EPSD;PhosphoSitePlus	COSMIC	0.779	Down-regulation
TK_PDGFR_FLT3_Y	P36888	FLT3	P36888	FLT3	Y599	F594I	594	Missense	distal	-5	no	1.199	1.175	EPSD;PhosphoSitePlus	COSMIC	0.779	Down-regulation
TK_PDGFR_FLT3_Y	P36888	FLT3	P36888	FLT3	Y599	V592D	592	Missense	distal	-7	no	1.199	1.212	EPSD;PhosphoSitePlus	COSMIC	0.779	Up-regulation
TK_PDGFR_FLT3_Y	P36888	FLT3	P36888	FLT3	Y599	Y599F	599	Missense	central	0	yes	1.199	0.000	EPSD;PhosphoSitePlus	COSMIC	0.779	Loss
TK_PDGFR_FLT3_Y	P36888	FLT3	P36888	FLT3	Y599	L601I	601	Missense	proximal	2	no	1.199	1.163	EPSD;PhosphoSitePlus	COSMIC	0.779	Down-regulation
TK_PDGFR_FLT3_Y	P36888	FLT3	P36888	FLT3	Y599	D593N	593	Missense	distal	-6	no	1.199	1.189	EPSD;PhosphoSitePlus	COSMIC	0.779	Down-regulation
TK_PDGFR_FLT3_Y	P36888	FLT3	P36888	FLT3	Y599	D593V	593	Missense	distal	-6	no	1.199	1.102	EPSD;PhosphoSitePlus	COSMIC	0.779	Down-regulation
TK_PDGFR_FLT3_Y	P36888	FLT3	P36888	FLT3	Y599	W603L	603	Missense	distal	4	no	1.199	1.314	EPSD;PhosphoSitePlus	COSMIC	0.779	Up-regulation
TK_PDGFR_FLT3_Y	P36888	FLT3	P36888	FLT3	Y599	E598G	598	Missense	proximal	-1	no	1.199	1.236	EPSD;PhosphoSitePlus	COSMIC	0.779	Up-regulation
TK_PDGFR_FLT3_Y	P36888	FLT3	P36888	FLT3	Y599	L601F	601	Missense	proximal	2	no	1.199	1.166	EPSD;PhosphoSitePlus	COSMIC	0.779	Down-regulation
TK_PDGFR_FLT3_Y	P36888	FLT3	P36888	FLT3	Y599	F594S	594	Missense	distal	-5	no	1.199	1.200	EPSD;PhosphoSitePlus	COSMIC	0.779	Up-regulation
TK_PDGFR_FLT3_Y	P36888	FLT3	P36888	FLT3	Y599	K602I	602	Missense	distal	3	no	1.199	1.193	EPSD;PhosphoSitePlus	COSMIC	0.779	Down-regulation
TK_PDGFR_FLT3_Y	P36888	FLT3	P36888	FLT3	Y599	Y597F	597	Missense	proximal	-2	no	1.199	1.185	EPSD;PhosphoSitePlus	COSMIC	0.779	Down-regulation
TK_PDGFR_FLT3_Y	P36888	FLT3	P36888	FLT3	Y599	E598D	598	Missense	proximal	-1	no	1.199	1.212	EPSD;PhosphoSitePlus	COSMIC	0.779	Up-regulation
TK_PDGFR_FLT3_Y	P36888	FLT3	P36888	FLT3	Y599	V592G	592	Missense	distal	-7	no	1.199	1.228	EPSD;PhosphoSitePlus	COSMIC	0.779	Up-regulation
TK_PDGFR_FLT3_Y	P36888	FLT3	P36888	FLT3	Y726	E720V	720	Missense	distal	-6	no	1.198	1.164	EPSD;PhosphoSitePlus	COSMIC	0.779	Down-regulation
TK_PDGFR_FLT3_Y	P36888	FLT3	P36888	FLT3	Y726	E720K	720	Missense	distal	-6	no	1.198	1.237	EPSD;PhosphoSitePlus	COSMIC;CCLE	0.779	Up-regulation
TK_PDGFR_FLT3_Y	P36888	FLT3	P36888	FLT3	Y793	E800K	800	Missense	distal	7	no	0.779	0.841	EPSD	COSMIC	0.779	Up-regulation
TK_PDGFR_FLT3_Y	P36888	FLT3	P36888	FLT3	Y793	V795I	795	Missense	proximal	2	no	0.779	0.784	EPSD	COSMIC	0.779	Up-regulation
TK_PDGFR_FLT3_Y	P36888	FLT3	P36888	FLT3	Y793	L788I	788	Missense	distal	-5	no	0.779	0.846	EPSD	COSMIC	0.779	Up-regulation
TK_PDGFR_FLT3_Y	P36888	FLT3	P36888	FLT3	Y793	A796D	796	Missense	distal	3	no	0.779	0.802	EPSD	COSMIC	0.779	Up-regulation
TK_PDGFR_FLT3_Y	P36888	FLT3	P36888	FLT3	Y793	E800Q	800	Missense	distal	7	no	0.779	0.824	EPSD	COSMIC	0.779	Up-regulation
TK_PDGFR_FLT3_Y	P36888	FLT3	P36888	FLT3	Y793	M799I	799	Missense	distal	6	no	0.779	0.806	EPSD	COSMIC	0.779	Up-regulation
TK_PDGFR_FLT3_Y	P36888	FLT3	P36888	FLT3	Y842	D835X	835	Missense	distal	-7	no	1.234	1.240	EPSD;PhosphoSitePlus	COSMIC	0.779	Up-regulation
TK_PDGFR_FLT3_Y	P36888	FLT3	P36888	FLT3	Y842	D839G	839	Missense	distal	-3	no	1.234	1.110	EPSD;PhosphoSitePlus	COSMIC	0.779	Down-regulation
TK_PDGFR_FLT3_Y	P36888	FLT3	P36888	FLT3	Y842	I836H	836	Missense	distal	-6	no	1.234	1.153	EPSD;PhosphoSitePlus	COSMIC	0.779	Down-regulation
TK_PDGFR_FLT3_Y	P36888	FLT3	P36888	FLT3	Y842	D839E	839	Missense	distal	-3	no	1.234	1.289	EPSD;PhosphoSitePlus	COSMIC	0.779	Up-regulation
TK_PDGFR_FLT3_Y	P36888	FLT3	P36888	FLT3	Y842	I836M	836	Missense	distal	-6	no	1.234	1.199	EPSD;PhosphoSitePlus	COSMIC	0.779	Down-regulation
TK_PDGFR_FLT3_Y	P36888	FLT3	P36888	FLT3	Y842	I836F	836	Missense	distal	-6	no	1.234	1.197	EPSD;PhosphoSitePlus	COSMIC	0.779	Down-regulation
TK_PDGFR_FLT3_Y	P36888	FLT3	P36888	FLT3	Y842	N841T	841	Missense	proximal	-1	no	1.234	1.224	EPSD;PhosphoSitePlus	COSMIC	0.779	Down-regulation
TK_PDGFR_FLT3_Y	P36888	FLT3	P36888	FLT3	Y842	D835A	835	Missense	distal	-7	no	1.234	1.227	EPSD;PhosphoSitePlus	COSMIC	0.779	Down-regulation
TK_PDGFR_FLT3_Y	P36888	FLT3	P36888	FLT3	Y842	I836D	836	Missense	distal	-6	no	1.234	1.274	EPSD;PhosphoSitePlus	COSMIC	0.779	Up-regulation
TK_PDGFR_FLT3_Y	P36888	FLT3	P36888	FLT3	Y842	D839X	839	Missense	distal	-3	no	1.234	1.210	EPSD;PhosphoSitePlus	COSMIC	0.779	Down-regulation
TK_PDGFR_FLT3_Y	P36888	FLT3	P36888	FLT3	Y842	D835I	835	Missense	distal	-7	no	1.234	1.236	EPSD;PhosphoSitePlus	COSMIC	0.779	Up-regulation
TK_PDGFR_FLT3_Y	P36888	FLT3	P36888	FLT3	Y842	D835G	835	Missense	distal	-7	no	1.234	1.249	EPSD;PhosphoSitePlus	COSMIC	0.779	Up-regulation
TK_PDGFR_FLT3_Y	P36888	FLT3	P36888	FLT3	Y842	D835F	835	Missense	distal	-7	no	1.234	1.249	EPSD;PhosphoSitePlus	COSMIC	0.779	Up-regulation
TK_PDGFR_FLT3_Y	P36888	FLT3	P36888	FLT3	Y842	A848P	848	Missense	distal	6	no	1.234	1.181	EPSD;PhosphoSitePlus	COSMIC	0.779	Down-regulation
TK_PDGFR_FLT3_Y	P36888	FLT3	P36888	FLT3	Y842	S838N	838	Missense	distal	-4	no	1.234	1.188	EPSD;PhosphoSitePlus	COSMIC	0.779	Down-regulation
TK_PDGFR_FLT3_Y	P36888	FLT3	P36888	FLT3	Y842	M837I	837	Missense	distal	-5	no	1.234	1.220	EPSD;PhosphoSitePlus	COSMIC	0.779	Down-regulation
TK_PDGFR_FLT3_Y	P36888	FLT3	P36888	FLT3	Y842	N841I	841	Missense	proximal	-1	no	1.234	1.220	EPSD;PhosphoSitePlus	COSMIC	0.779	Down-regulation
TK_PDGFR_FLT3_Y	P36888	FLT3	P36888	FLT3	Y842	N847D	847	Missense	distal	5	no	1.234	1.240	EPSD;PhosphoSitePlus	COSMIC	0.779	Up-regulation
TK_PDGFR_FLT3_Y	P36888	FLT3	P36888	FLT3	Y842	Y842H	842	Missense	central	0	yes	1.234	0.000	EPSD;PhosphoSitePlus	COSMIC	0.779	Loss
TK_PDGFR_FLT3_Y	P36888	FLT3	P36888	FLT3	Y842	D839N	839	Missense	distal	-3	no	1.234	1.175	EPSD;PhosphoSitePlus	COSMIC	0.779	Down-regulation
TK_PDGFR_FLT3_Y	P36888	FLT3	P36888	FLT3	Y842	N841Y	841	Missense	proximal	-1	no	1.234	1.223	EPSD;PhosphoSitePlus	COSMIC	0.779	Down-regulation
TK_PDGFR_FLT3_Y	P36888	FLT3	P36888	FLT3	Y842	I836L	836	Missense	distal	-6	no	1.234	1.364	EPSD;PhosphoSitePlus	COSMIC	0.779	Up-regulation
TK_PDGFR_FLT3_Y	P36888	FLT3	P36888	FLT3	Y842	I836S	836	Missense	distal	-6	no	1.234	1.142	EPSD;PhosphoSitePlus	COSMIC	0.779	Down-regulation
TK_PDGFR_FLT3_Y	P36888	FLT3	P36888	FLT3	Y842	I836V	836	Missense	distal	-6	no	1.234	1.177	EPSD;PhosphoSitePlus	COSMIC	0.779	Down-regulation
TK_PDGFR_FLT3_Y	P36888	FLT3	P36888	FLT3	Y842	M837P	837	Missense	distal	-5	no	1.234	1.230	EPSD;PhosphoSitePlus	COSMIC	0.779	Down-regulation
TK_PDGFR_FLT3_Y	P36888	FLT3	P36888	FLT3	Y842	V843I	843	Missense	proximal	1	no	1.234	1.224	EPSD;PhosphoSitePlus	COSMIC	0.779	Down-regulation
TK_PDGFR_FLT3_Y	P36888	FLT3	P36888	FLT3	Y842	S838G	838	Missense	distal	-4	no	1.234	1.089	EPSD;PhosphoSitePlus	COSMIC	0.779	Down-regulation
TK_PDGFR_FLT3_Y	P36888	FLT3	P36888	FLT3	Y842	R845G	845	Missense	distal	3	no	1.234	1.260	EPSD;PhosphoSitePlus	COSMIC	0.779	Up-regulation
TK_PDGFR_FLT3_Y	P36888	FLT3	P36888	FLT3	Y842	I836X	836	Missense	distal	-6	no	1.234	1.219	EPSD;PhosphoSitePlus	COSMIC	0.779	Down-regulation
TK_PDGFR_FLT3_Y	P36888	FLT3	P36888	FLT3	Y842	N841H	841	Missense	proximal	-1	no	1.234	1.218	EPSD;PhosphoSitePlus	COSMIC	0.779	Down-regulation
TK_PDGFR_FLT3_Y	P36888	FLT3	P36888	FLT3	Y842	I836T	836	Missense	distal	-6	no	1.234	1.157	EPSD;PhosphoSitePlus	COSMIC	0.779	Down-regulation
TK_PDGFR_FLT3_Y	P36888	FLT3	P36888	FLT3	Y955	Y955C	955	Missense	central	0	yes	1.584	0.000	PhosphoSitePlus;EPSD	COSMIC	0.779	Loss
TK_PDGFR_FLT3_Y	P36888	FLT3	P36888	FLT3	Y955	D949N	949	Missense	distal	-6	no	1.584	1.575	PhosphoSitePlus;EPSD	COSMIC	0.779	Down-regulation
TK_PDGFR_FLT3_Y	P36888	FLT3	P36888	FLT3	Y955	R961S	961	Missense	distal	6	no	1.584	1.564	PhosphoSitePlus;EPSD	COSMIC;CCLE	0.779	Down-regulation
TK_PDGFR_FLT3_Y	P36888	FLT3	P36888	FLT3	Y955	Q956E	956	Missense	proximal	1	no	1.584	1.625	PhosphoSitePlus;EPSD	COSMIC	0.779	Up-regulation
TK_PDGFR_FLT3_Y	P36888	FLT3	P36888	FLT3	Y955	G960S	960	Missense	distal	5	no	1.584	1.596	PhosphoSitePlus;EPSD	COSMIC	0.779	Up-regulation
TK_PDGFR_FLT3_Y	P36888	FLT3	P36888	FLT3	Y955	A953E	953	Missense	proximal	-2	no	1.584	1.567	PhosphoSitePlus;EPSD	COSMIC	0.779	Down-regulation
TK_PDGFR_FLT3_Y	P36888	FLT3	P36888	FLT3	Y955	E952D	952	Missense	distal	-3	no	1.584	1.529	PhosphoSitePlus;EPSD	COSMIC	0.779	Down-regulation
TK_PDGFR_FLT3_Y	P36888	FLT3	P36888	FLT3	Y955	R961H	961	Missense	distal	6	no	1.584	1.629	PhosphoSitePlus;EPSD	COSMIC	0.779	Up-regulation
TK_PDGFR_FLT3_Y	P36888	FLT3	P36888	FLT3	Y969	E964K	964	Missense	distal	-5	no	1.490	1.457	EPSD;PhosphoSitePlus	COSMIC	0.779	Down-regulation
TK_PDGFR_FLT3_Y	P36888	FLT3	P36888	FLT3	Y969	F975L	975	Missense	distal	6	no	1.490	1.362	EPSD;PhosphoSitePlus	COSMIC	0.779	Down-regulation
TK_PDGFR_FLT3_Y	P36888	FLT3	P36888	FLT3	Y969	S976R	976	Missense	distal	7	no	1.490	1.519	EPSD;PhosphoSitePlus	COSMIC	0.779	Up-regulation
TK_PDGFR_FLT3_Y	P36888	FLT3	P36888	FLT3	Y969	P974L	974	Missense	distal	5	no	1.490	1.463	EPSD;PhosphoSitePlus	COSMIC	0.779	Down-regulation
TK_PDGFR_FLT3_Y	P36888	FLT3	P36888	FLT3	Y969	P966S	966	Missense	distal	-3	no	1.490	1.434	EPSD;PhosphoSitePlus	COSMIC	0.779	Down-regulation
TK_PDGFR_FLT3_Y	Q15118	PDK1	P36888	FLT3	Y243	R238H	238	Missense	distal	-5	no	1.394	1.412	PhosphoSitePlus	COSMIC	0.779	Up-regulation
TK_PDGFR_FLT3_Y	Q15118	PDK1	P36888	FLT3	Y243	A236D	236	Missense	distal	-7	no	1.394	1.401	PhosphoSitePlus	COSMIC	0.779	Up-regulation
CMGC_SRPK_SRPK1_ST	Q96SB4	SRPK1	Q96SB4	SRPK1	S39	Q44R	44	Missense	distal	5	no	40.332	60.954	EPSD	COSMIC	48.822	Gain
CMGC_SRPK_SRPK1_ST	Q96SB4	SRPK1	Q96SB4	SRPK1	S249	G248R	248	Missense	proximal	-1	no	57.729	85.459	EPSD	COSMIC;GDSC	48.822	Up-regulation
CMGC_SRPK_SRPK1_ST	Q96SB4	SRPK1	Q96SB4	SRPK1	S249	P245L	245	Missense	distal	-4	no	57.729	55.251	EPSD	COSMIC;GDSC;CCLE	48.822	Down-regulation
CMGC_SRPK_SRPK1_ST	Q96SB4	SRPK1	Q96SB4	SRPK1	S587	S587F	587	Missense	central	0	yes	54.494	0.000	EPSD;PhosphoSitePlus	COSMIC	48.822	Loss
CMGC_SRPK_SRPK1_ST	Q96SB4	SRPK1	Q96SB4	SRPK1	S587	G584E	584	Missense	distal	-3	no	54.494	55.352	EPSD;PhosphoSitePlus	COSMIC	48.822	Up-regulation
CMGC_SRPK_SRPK1_ST	Q96SB4	SRPK1	Q96SB4	SRPK1	S587	Y586N	586	Missense	proximal	-1	no	54.494	55.129	EPSD;PhosphoSitePlus	COSMIC	48.822	Up-regulation
CMGC_SRPK_SRPK1_ST	Q07955	SRSF1	Q96SB4	SRPK1	S91	V86M	86	Missense	distal	-5	no	55.432	57.308	EPSD	COSMIC	48.822	Up-regulation
CMGC_SRPK_SRPK1_ST	Q07955	SRSF1	Q96SB4	SRPK1	S91	R97L	97	Missense	distal	6	no	55.432	47.775	EPSD	COSMIC	48.822	Loss
CMGC_SRPK_SRPK1_ST	Q07955	SRSF1	Q96SB4	SRPK1	S91	P89S	89	Missense	proximal	-2	no	55.432	65.143	EPSD	COSMIC;GDSC;CCLE	48.822	Up-regulation
CMGC_SRPK_SRPK1_ST	Q07955	SRSF1	Q96SB4	SRPK1	S91	R85Q	85	Missense	distal	-6	no	55.432	52.400	EPSD	COSMIC	48.822	Down-regulation
CMGC_SRPK_SRPK1_ST	Q07955	SRSF1	Q96SB4	SRPK1	S91	T95I	95	Missense	distal	4	no	55.432	56.528	EPSD	COSMIC	48.822	Up-regulation
CMGC_SRPK_SRPK1_ST	Q07955	SRSF1	Q96SB4	SRPK1	S131	W134L	134	Missense	distal	3	no	50.381	49.474	EPSD	COSMIC	48.822	Down-regulation
CMGC_SRPK_SRPK1_ST	Q07955	SRSF1	Q96SB4	SRPK1	S131	P130A	130	Missense	proximal	-1	no	50.381	42.984	EPSD	COSMIC	48.822	Loss
CMGC_SRPK_SRPK1_ST	Q07955	SRSF1	Q96SB4	SRPK1	S131	W134C	134	Missense	distal	3	no	50.381	50.054	EPSD	COSMIC	48.822	Down-regulation
CMGC_SRPK_SRPK1_ST	Q07955	SRSF1	Q96SB4	SRPK1	S131	Q135R	135	Missense	distal	4	no	50.381	55.248	EPSD	COSMIC	48.822	Up-regulation
CMGC_SRPK_SRPK1_ST	Q07955	SRSF1	Q96SB4	SRPK1	S182	T187I	187	Missense	distal	5	no	62.623	61.621	EPSD	COSMIC	48.822	Down-regulation
CMGC_SRPK_SRPK1_ST	Q07955	SRSF1	Q96SB4	SRPK1	S182	H183R	183	Missense	proximal	1	no	62.623	79.478	EPSD	COSMIC	48.822	Up-regulation
CMGC_SRPK_SRPK1_ST	Q07955	SRSF1	Q96SB4	SRPK1	S182	S182F	182	Missense	central	0	yes	62.623	0.000	EPSD	COSMIC	48.822	Loss
CMGC_SRPK_SRPK1_ST	Q07955	SRSF1	Q96SB4	SRPK1	S182	E184K	184	Missense	proximal	2	no	62.623	67.615	EPSD	COSMIC	48.822	Up-regulation
CMGC_SRPK_SRPK1_ST	Q07955	SRSF1	Q96SB4	SRPK1	S242	R247H	247	Missense	distal	5	no	125.873	105.113	EPSD	COSMIC	48.822	Down-regulation
CMGC_SRPK_SRPK1_ST	Q07955	SRSF1	Q96SB4	SRPK1	S244	R247H	247	Missense	distal	3	no	126.258	105.737	EPSD	COSMIC	48.822	Down-regulation
CMGC_SRPK_SRPK1_ST	Q07955	SRSF1	Q96SB4	SRPK1	S246	R247H	247	Missense	proximal	1	no	135.367	118.512	EPSD	COSMIC	48.822	Down-regulation
CMGC_SRPK_SRPK1_ST	Q07955	SRSF1	Q96SB4	SRPK1	T248	R247H	247	Missense	proximal	-1	no	116.514	88.581	EPSD	COSMIC	48.822	Down-regulation
CMGC_SRPK_SRPK1_ST	Q9BWF3	RBM4	Q96SB4	SRPK1	S160	R164Q	164	Missense	distal	4	no	51.916	47.049	EPSD	COSMIC	48.822	Loss
CMGC_SRPK_SRPK1_ST	Q9BWF3	RBM4	Q96SB4	SRPK1	S309	R313C	313	Missense	distal	4	no	96.030	91.607	PhosphoSitePlus	COSMIC	48.822	Down-regulation
CMGC_SRPK_SRPK1_ST	Q9BWF3	RBM4	Q96SB4	SRPK1	S309	A316G	316	Missense	distal	7	no	96.030	97.672	PhosphoSitePlus	COSMIC;GDSC;CCLE	48.822	Up-regulation
CMGC_SRPK_SRPK1_ST	Q9BWF3	RBM4	Q96SB4	SRPK1	S309	R306W	306	Missense	distal	-3	no	96.030	55.551	PhosphoSitePlus	COSMIC	48.822	Down-regulation
CMGC_SRPK_SRPK1_ST	Q9BWF3	RBM4	Q96SB4	SRPK1	T315	P319S	319	Missense	distal	4	no	79.940	86.030	EPSD	COSMIC	48.822	Up-regulation
CMGC_SRPK_SRPK1_ST	Q9BWF3	RBM4	Q96SB4	SRPK1	T315	R313C	313	Missense	proximal	-2	no	79.940	75.104	EPSD	COSMIC	48.822	Down-regulation
CMGC_SRPK_SRPK1_ST	Q9BWF3	RBM4	Q96SB4	SRPK1	T315	A316G	316	Missense	proximal	1	no	79.940	82.594	EPSD	COSMIC;GDSC;CCLE	48.822	Up-regulation
CMGC_SRPK_SRPK1_ST	Q9Y5S9	RBM8A	Q96SB4	SRPK1	S56	E63K	63	Missense	distal	7	no	61.208	61.135	EPSD	COSMIC	48.822	Down-regulation
CMGC_SRPK_SRPK1_ST	Q9Y5S9	RBM8A	Q96SB4	SRPK1	S56	E58K	58	Missense	proximal	2	no	61.208	66.199	EPSD	COSMIC	48.822	Up-regulation
CMGC_SRPK_SRPK1_ST	Q9Y5S9	RBM8A	Q96SB4	SRPK1	S166	R165H	165	Missense	proximal	-1	no	184.253	156.319	EPSD;PhosphoSitePlus	COSMIC	48.822	Down-regulation
CMGC_SRPK_SRPK1_ST	Q9Y5S9	RBM8A	Q96SB4	SRPK1	S166	P169S	169	Missense	distal	3	no	184.253	182.833	EPSD;PhosphoSitePlus	COSMIC	48.822	Down-regulation
CMGC_SRPK_SRPK1_ST	Q9Y5S9	RBM8A	Q96SB4	SRPK1	S166	R171W	171	Missense	distal	5	no	184.253	162.085	EPSD;PhosphoSitePlus	COSMIC	48.822	Down-regulation
CMGC_SRPK_SRPK1_ST	Q9Y5S9	RBM8A	Q96SB4	SRPK1	S166	R172H	172	Missense	distal	6	no	184.253	176.380	EPSD;PhosphoSitePlus	COSMIC	48.822	Down-regulation
CMGC_SRPK_SRPK1_ST	Q9Y5S9	RBM8A	Q96SB4	SRPK1	S166	R163I	163	Missense	distal	-3	no	184.253	141.140	EPSD;PhosphoSitePlus	COSMIC	48.822	Down-regulation
CMGC_SRPK_SRPK1_ST	Q9Y5S9	RBM8A	Q96SB4	SRPK1	S166	R159I	159	Missense	distal	-7	no	184.253	164.616	EPSD;PhosphoSitePlus	COSMIC	48.822	Down-regulation
CMGC_SRPK_SRPK1_ST	Q9Y5S9	RBM8A	Q96SB4	SRPK1	S166	R172L	172	Missense	distal	6	no	184.253	176.595	EPSD;PhosphoSitePlus	COSMIC	48.822	Down-regulation
CMGC_SRPK_SRPK1_ST	Q9Y5S9	RBM8A	Q96SB4	SRPK1	S166	R164H	164	Missense	proximal	-2	no	184.253	178.927	EPSD;PhosphoSitePlus	COSMIC	48.822	Down-regulation
CMGC_SRPK_SRPK1_ST	Q9Y5S9	RBM8A	Q96SB4	SRPK1	S166	R171T	171	Missense	distal	5	no	184.253	161.615	EPSD;PhosphoSitePlus	COSMIC	48.822	Down-regulation
CMGC_SRPK_SRPK1_ST	Q9Y5S9	RBM8A	Q96SB4	SRPK1	S168	R165H	165	Missense	distal	-3	no	189.678	151.987	PhosphoSitePlus;EPSD	COSMIC	48.822	Down-regulation
CMGC_SRPK_SRPK1_ST	Q9Y5S9	RBM8A	Q96SB4	SRPK1	S168	P169S	169	Missense	proximal	1	no	189.678	188.534	PhosphoSitePlus;EPSD	COSMIC	48.822	Down-regulation
CMGC_SRPK_SRPK1_ST	Q9Y5S9	RBM8A	Q96SB4	SRPK1	S168	R171W	171	Missense	distal	3	no	189.678	167.706	PhosphoSitePlus;EPSD	COSMIC	48.822	Down-regulation
CMGC_SRPK_SRPK1_ST	Q9Y5S9	RBM8A	Q96SB4	SRPK1	S168	R172H	172	Missense	distal	4	no	189.678	185.012	PhosphoSitePlus;EPSD	COSMIC	48.822	Down-regulation
CMGC_SRPK_SRPK1_ST	Q9Y5S9	RBM8A	Q96SB4	SRPK1	S168	R163I	163	Missense	distal	-5	no	189.678	176.861	PhosphoSitePlus;EPSD	COSMIC	48.822	Down-regulation
CMGC_SRPK_SRPK1_ST	Q9Y5S9	RBM8A	Q96SB4	SRPK1	S168	R172L	172	Missense	distal	4	no	189.678	185.395	PhosphoSitePlus;EPSD	COSMIC	48.822	Down-regulation
CMGC_SRPK_SRPK1_ST	Q9Y5S9	RBM8A	Q96SB4	SRPK1	S168	R164H	164	Missense	distal	-4	no	189.678	186.385	PhosphoSitePlus;EPSD	COSMIC	48.822	Down-regulation
CMGC_SRPK_SRPK1_ST	Q9Y5S9	RBM8A	Q96SB4	SRPK1	S168	R171T	171	Missense	distal	3	no	189.678	167.237	PhosphoSitePlus;EPSD	COSMIC	48.822	Down-regulation
AGC_PKC_PKCi_PRKCZ_ST	P60484	PTEN	Q05513	PRKCZ	S179	L181R	181	Missense	proximal	2	no	25.642	33.110	EPSD	COSMIC	31.494	Gain
AGC_PKC_PKCi_PRKCZ_ST	P60484	PTEN	Q05513	PRKCZ	T232	G230R	230	Missense	proximal	-2	no	22.361	33.055	EPSD	COSMIC	31.494	Gain
AGC_PKC_PKCi_PRKCZ_ST	P60484	PTEN	Q05513	PRKCZ	T232	E235K	235	Missense	distal	3	no	22.361	31.804	EPSD	COSMIC	31.494	Gain
AGC_PKC_PKCi_PRKCZ_ST	P60484	PTEN	Q05513	PRKCZ	S380	D375N	375	Missense	distal	-5	no	40.810	39.699	PhosphoSitePlus;EPSD	COSMIC	31.494	Down-regulation
AGC_PKC_PKCi_PRKCZ_ST	P60484	PTEN	Q05513	PRKCZ	S380	T383I	383	Missense	distal	3	no	40.810	36.598	PhosphoSitePlus;EPSD	COSMIC	31.494	Down-regulation
AGC_PKC_PKCi_PRKCZ_ST	P60484	PTEN	Q05513	PRKCZ	S380	D384N	384	Missense	distal	4	no	40.810	46.756	PhosphoSitePlus;EPSD	COSMIC	31.494	Up-regulation
AGC_PKC_PKCi_PRKCZ_ST	P60484	PTEN	Q05513	PRKCZ	S380	T382S	382	Missense	proximal	2	no	40.810	39.720	PhosphoSitePlus;EPSD	COSMIC	31.494	Down-regulation
AGC_PKC_PKCi_PRKCZ_ST	P60484	PTEN	Q05513	PRKCZ	S380	D384G	384	Missense	distal	4	no	40.810	42.338	PhosphoSitePlus;EPSD	COSMIC	31.494	Up-regulation
AGC_PKC_PKCi_PRKCZ_ST	Q9Y6Q9	NCOA3	Q05513	PRKCZ	S13	A12T	12	Missense	proximal	-1	no	33.562	32.614	EPSD	COSMIC	31.494	Down-regulation
AGC_PKC_PKCi_PRKCZ_ST	Q9Y6Q9	NCOA3	Q05513	PRKCZ	S13	R18C	18	Missense	distal	5	no	33.562	32.856	EPSD	COSMIC	31.494	Down-regulation
AGC_PKC_PKCi_PRKCZ_ST	Q9Y6Q9	NCOA3	Q05513	PRKCZ	S13	K19R	19	Missense	distal	6	no	33.562	36.842	EPSD	COSMIC	31.494	Up-regulation
AGC_PKC_PKCi_PRKCZ_ST	Q9Y6Q9	NCOA3	Q05513	PRKCZ	S13	L20W	20	Missense	distal	7	no	33.562	35.957	EPSD	COSMIC	31.494	Up-regulation
AGC_PKC_PKCi_PRKCZ_ST	Q9Y6Q9	NCOA3	Q05513	PRKCZ	S274	V277A	277	Missense	distal	3	no	23.739	33.132	EPSD	COSMIC	31.494	Gain
AGC_PKC_PKCi_PRKCZ_ST	Q9Y6Q9	NCOA3	Q05513	PRKCZ	S284	M289L	289	Missense	distal	5	no	32.993	32.664	EPSD	COSMIC	31.494	Down-regulation
AGC_PKC_PKCi_PRKCZ_ST	Q9Y6Q9	NCOA3	Q05513	PRKCZ	S284	S288F	288	Missense	distal	4	no	32.993	20.778	EPSD	COSMIC	31.494	Loss
AGC_PKC_PKCi_PRKCZ_ST	Q9Y6Q9	NCOA3	Q05513	PRKCZ	S284	R286K	286	Missense	proximal	2	no	32.993	30.451	EPSD	COSMIC	31.494	Loss
AGC_PKC_PKCi_PRKCZ_ST	Q9Y6Q9	NCOA3	Q05513	PRKCZ	S284	V277A	277	Missense	distal	-7	no	32.993	36.937	EPSD	COSMIC	31.494	Up-regulation
AGC_PKC_PKCi_PRKCZ_ST	Q9Y6Q9	NCOA3	Q05513	PRKCZ	S284	T282P	282	Missense	proximal	-2	no	32.993	30.287	EPSD	COSMIC	31.494	Loss
AGC_PKC_PKCi_PRKCZ_ST	Q9Y6Q9	NCOA3	Q05513	PRKCZ	S306	R303I	303	Missense	distal	-3	no	39.116	19.970	EPSD	COSMIC	31.494	Loss
AGC_PKC_PKCi_PRKCZ_ST	Q9Y6Q9	NCOA3	Q05513	PRKCZ	S563	D566Y	566	Missense	distal	3	no	32.930	26.039	EPSD	COSMIC	31.494	Loss
AGC_PKC_PKCi_PRKCZ_ST	Q9Y6Q9	NCOA3	Q05513	PRKCZ	S563	N564S	564	Missense	proximal	1	no	32.930	32.406	EPSD	COSMIC	31.494	Down-regulation
AGC_PKC_PKCi_PRKCZ_ST	Q9Y6Q9	NCOA3	Q05513	PRKCZ	S598	S594G	594	Missense	distal	-4	no	31.950	31.890	EPSD	COSMIC	31.494	Down-regulation
AGC_PKC_PKCi_PRKCZ_ST	Q9Y6Q9	NCOA3	Q05513	PRKCZ	S598	S601N	601	Missense	distal	3	no	31.950	34.135	EPSD	COSMIC	31.494	Up-regulation
AGC_PKC_PKCi_PRKCZ_ST	Q9Y6Q9	NCOA3	Q05513	PRKCZ	S598	S598R	598	Missense	central	0	yes	31.950	0.000	EPSD	COSMIC	31.494	Loss
AGC_PKC_PKCi_PRKCZ_ST	Q9Y6Q9	NCOA3	Q05513	PRKCZ	S598	L593H	593	Missense	distal	-5	no	31.950	29.770	EPSD	COSMIC	31.494	Loss
AGC_PKC_PKCi_PRKCZ_ST	Q9Y6Q9	NCOA3	Q05513	PRKCZ	S598	G605W	605	Missense	distal	7	no	31.950	32.767	EPSD	COSMIC	31.494	Up-regulation
AGC_PKC_PKCi_PRKCZ_ST	Q9Y6Q9	NCOA3	Q05513	PRKCZ	S601	S598R	598	Missense	distal	-3	no	21.902	35.328	EPSD	COSMIC	31.494	Gain
AGC_PKC_PKCi_PRKCZ_ST	Q9Y6Q9	NCOA3	Q05513	PRKCZ	S767	N764Y	764	Missense	distal	-3	no	31.044	34.591	EPSD	COSMIC	31.494	Gain
AGC_PKC_PKCi_PRKCZ_ST	Q9Y6Q9	NCOA3	Q05513	PRKCZ	S1033	R1031M	1031	Missense	proximal	-2	no	35.139	25.731	EPSD;PhosphoSitePlus	COSMIC	31.494	Loss
AGC_PKC_PKCi_PRKCZ_ST	Q9Y6Q9	NCOA3	Q05513	PRKCZ	S1033	L1034M	1034	Missense	proximal	1	no	35.139	36.700	EPSD;PhosphoSitePlus	COSMIC	31.494	Up-regulation
AGC_PKC_PKCi_PRKCZ_ST	Q9Y6Q9	NCOA3	Q05513	PRKCZ	S1033	L1029V	1029	Missense	distal	-4	no	35.139	35.063	EPSD;PhosphoSitePlus	COSMIC	31.494	Down-regulation
AGC_PKC_PKCi_PRKCZ_ST	Q9Y6Q9	NCOA3	Q05513	PRKCZ	S1033	R1027M	1027	Missense	distal	-6	no	35.139	35.473	EPSD;PhosphoSitePlus	COSMIC	31.494	Up-regulation
AGC_PKC_PKCi_PRKCZ_ST	Q9Y6Q9	NCOA3	Q05513	PRKCZ	S1033	L1029M	1029	Missense	distal	-4	no	35.139	34.657	EPSD;PhosphoSitePlus	COSMIC	31.494	Down-regulation
AGC_PKC_PKCi_PRKCZ_ST	Q9Y6Q9	NCOA3	Q05513	PRKCZ	S1042	E1045K	1045	Missense	distal	3	no	22.425	31.868	EPSD;PhosphoSitePlus	COSMIC	31.494	Gain
AGC_PKC_PKCi_PRKCZ_ST	Q9Y6Q9	NCOA3	Q05513	PRKCZ	S1048	E1050K	1050	Missense	proximal	2	no	23.430	33.037	EPSD;PhosphoSitePlus	COSMIC;GDSC;CCLE	31.494	Gain
AGC_PKC_PKCi_PRKCZ_ST	Q9Y6Q9	NCOA3	Q05513	PRKCZ	S1048	E1045K	1045	Missense	distal	-3	no	23.430	36.725	EPSD;PhosphoSitePlus	COSMIC	31.494	Gain
AGC_PKC_PKCi_PRKCZ_ST	Q9Y6Q9	NCOA3	Q05513	PRKCZ	T1059	N1063S	1063	Missense	distal	4	no	33.442	33.227	PhosphoSitePlus;EPSD	COSMIC	31.494	Down-regulation
AGC_PKC_PKCi_PRKCZ_ST	Q9Y6Q9	NCOA3	Q05513	PRKCZ	S1062	N1063S	1063	Missense	proximal	1	no	41.445	40.922	EPSD;PhosphoSitePlus	COSMIC	31.494	Down-regulation
AGC_PKC_PKCi_PRKCZ_ST	Q9Y6Q9	NCOA3	Q05513	PRKCZ	T1067	E1071A	1071	Missense	distal	4	no	34.523	38.290	EPSD;PhosphoSitePlus	COSMIC	31.494	Up-regulation
AGC_PKC_PKCi_PRKCZ_ST	Q9Y6Q9	NCOA3	Q05513	PRKCZ	T1067	N1063S	1063	Missense	distal	-4	no	34.523	34.666	EPSD;PhosphoSitePlus	COSMIC	31.494	Up-regulation
AGC_PKC_PKCi_PRKCZ_ST	Q16625	OCLN	Q05513	PRKCZ	S45	P48L	48	Missense	distal	3	no	27.128	34.976	EPSD	COSMIC	31.494	Gain
AGC_PKC_PKCi_PRKCZ_ST	Q16625	OCLN	Q05513	PRKCZ	S302	V308M	308	Missense	distal	6	no	34.086	34.827	EPSD	COSMIC;GDSC	31.494	Up-regulation
AGC_PKC_PKCi_PRKCZ_ST	Q16625	OCLN	Q05513	PRKCZ	S302	K299N	299	Missense	distal	-3	no	34.086	26.330	EPSD	COSMIC	31.494	Loss
AGC_PKC_PKCi_PRKCZ_ST	Q16625	OCLN	Q05513	PRKCZ	S302	W297C	297	Missense	distal	-5	no	34.086	33.983	EPSD	COSMIC	31.494	Down-regulation
AGC_PKC_PKCi_PRKCZ_ST	Q16625	OCLN	Q05513	PRKCZ	S302	V308A	308	Missense	distal	6	no	34.086	36.007	EPSD	COSMIC	31.494	Up-regulation
AGC_PKC_PKCi_PRKCZ_ST	Q16625	OCLN	Q05513	PRKCZ	S302	W297L	297	Missense	distal	-5	no	34.086	33.951	EPSD	COSMIC;GDSC	31.494	Down-regulation
AGC_PKC_PKCi_PRKCZ_ST	Q16625	OCLN	Q05513	PRKCZ	S321	R318I	318	Missense	distal	-3	no	42.426	23.281	EPSD	COSMIC	31.494	Loss
AGC_PKC_PKCi_PRKCZ_ST	Q16625	OCLN	Q05513	PRKCZ	S369	G372D	372	Missense	distal	3	no	32.247	30.733	EPSD	COSMIC	31.494	Loss
AGC_PKC_PKCi_PRKCZ_ST	Q7KZI7	MARK2	Q05513	PRKCZ	S30	L24V	24	Missense	distal	-6	no	33.883	33.975	EPSD	COSMIC	31.494	Up-regulation
AGC_PKC_PKCi_PRKCZ_ST	Q7KZI7	MARK2	Q05513	PRKCZ	S43	I50V	50	Missense	distal	7	no	35.026	32.376	EPSD	COSMIC	31.494	Down-regulation
AGC_PKC_PKCi_PRKCZ_ST	Q7KZI7	MARK2	Q05513	PRKCZ	S43	E46K	46	Missense	distal	3	no	35.026	44.469	EPSD	COSMIC	31.494	Up-regulation
AGC_PKC_PKCi_PRKCZ_ST	Q7KZI7	MARK2	Q05513	PRKCZ	S93	N90K	90	Missense	distal	-3	no	23.742	31.499	EPSD	COSMIC	31.494	Gain
AGC_PKC_PKCi_PRKCZ_ST	Q7KZI7	MARK2	Q05513	PRKCZ	T208	T201P	201	Missense	distal	-7	no	41.261	38.621	EPSD	COSMIC	31.494	Down-regulation
AGC_PKC_PKCi_PRKCZ_ST	Q7KZI7	MARK2	Q05513	PRKCZ	T208	P213S	213	Missense	distal	5	no	41.261	41.239	EPSD	COSMIC	31.494	Down-regulation
AGC_PKC_PKCi_PRKCZ_ST	Q7KZI7	MARK2	Q05513	PRKCZ	S290	K291N	291	Missense	proximal	1	no	38.492	38.224	EPSD	COSMIC	31.494	Down-regulation
AGC_PKC_PKCi_PRKCZ_ST	Q7KZI7	MARK2	Q05513	PRKCZ	S290	S290N	290	Missense	central	0	yes	38.492	0.000	EPSD	COSMIC	31.494	Loss
AGC_PKC_PKCi_PRKCZ_ST	Q7KZI7	MARK2	Q05513	PRKCZ	T294	K291N	291	Missense	distal	-3	no	44.382	36.625	EPSD	COSMIC	31.494	Down-regulation
AGC_PKC_PKCi_PRKCZ_ST	Q7KZI7	MARK2	Q05513	PRKCZ	T294	S290N	290	Missense	distal	-4	no	44.382	44.239	EPSD	COSMIC	31.494	Down-regulation
AGC_PKC_PKCi_PRKCZ_ST	Q7KZI7	MARK2	Q05513	PRKCZ	S409	R407H	407	Missense	proximal	-2	no	36.127	27.275	EPSD	COSMIC	31.494	Loss
AGC_PKC_PKCi_PRKCZ_ST	Q7KZI7	MARK2	Q05513	PRKCZ	S409	R406Q	406	Missense	distal	-3	no	36.127	24.240	EPSD	COSMIC	31.494	Loss
AGC_PKC_PKCi_PRKCZ_ST	Q7KZI7	MARK2	Q05513	PRKCZ	S443	S443F	443	Missense	central	0	yes	53.685	0.000	EPSD	COSMIC	31.494	Loss
AGC_PKC_PKCi_PRKCZ_ST	Q7KZI7	MARK2	Q05513	PRKCZ	S443	S448N	448	Missense	distal	5	no	53.685	54.045	EPSD	COSMIC	31.494	Up-regulation
AGC_PKC_PKCi_PRKCZ_ST	Q7KZI7	MARK2	Q05513	PRKCZ	S443	R436L	436	Missense	distal	-7	no	53.685	48.926	EPSD	COSMIC	31.494	Down-regulation
AGC_PKC_PKCi_PRKCZ_ST	Q7KZI7	MARK2	Q05513	PRKCZ	S443	S449N	449	Missense	distal	6	no	53.685	54.316	EPSD	COSMIC	31.494	Up-regulation
AGC_PKC_PKCi_PRKCZ_ST	Q7KZI7	MARK2	Q05513	PRKCZ	S443	P437S	437	Missense	distal	-6	no	53.685	53.408	EPSD	COSMIC	31.494	Down-regulation
AGC_PKC_PKCi_PRKCZ_ST	Q7KZI7	MARK2	Q05513	PRKCZ	T480	S477F	477	Missense	distal	-3	no	33.446	31.850	EPSD	COSMIC	31.494	Down-regulation
AGC_PKC_PKCi_PRKCZ_ST	Q7KZI7	MARK2	Q05513	PRKCZ	S533	P540L	540	Missense	distal	7	no	40.927	38.398	EPSD	COSMIC	31.494	Down-regulation
AGC_PKC_PKCi_PRKCZ_ST	Q7KZI7	MARK2	Q05513	PRKCZ	S533	R526W	526	Missense	distal	-7	no	40.927	32.775	EPSD	COSMIC	31.494	Down-regulation
AGC_PKC_PKCi_PRKCZ_ST	Q7KZI7	MARK2	Q05513	PRKCZ	S533	P527S	527	Missense	distal	-6	no	40.927	40.650	EPSD	COSMIC	31.494	Down-regulation
AGC_PKC_PKCi_PRKCZ_ST	Q7KZI7	MARK2	Q05513	PRKCZ	S533	P527Q	527	Missense	distal	-6	no	40.927	40.576	EPSD	COSMIC	31.494	Down-regulation
AGC_PKC_PKCi_PRKCZ_ST	Q7KZI7	MARK2	Q05513	PRKCZ	S533	A536V	536	Missense	distal	3	no	40.927	31.535	EPSD	COSMIC	31.494	Down-regulation
AGC_PKC_PKCi_PRKCZ_ST	Q7KZI7	MARK2	Q05513	PRKCZ	S533	S535F	535	Missense	proximal	2	no	40.927	39.876	EPSD	COSMIC	31.494	Down-regulation
AGC_PKC_PKCi_PRKCZ_ST	Q7KZI7	MARK2	Q05513	PRKCZ	T560	P562H	562	Missense	proximal	2	no	27.494	35.885	EPSD	COSMIC	31.494	Gain
AGC_PKC_PKCi_PRKCZ_ST	Q7KZI7	MARK2	Q05513	PRKCZ	S592	R589H	589	Missense	distal	-3	no	40.240	31.812	EPSD	COSMIC	31.494	Down-regulation
AGC_PKC_PKCi_PRKCZ_ST	Q7KZI7	MARK2	Q05513	PRKCZ	S592	P588S	588	Missense	distal	-4	no	40.240	39.841	EPSD	COSMIC	31.494	Down-regulation
AGC_PKC_PKCi_PRKCZ_ST	Q7KZI7	MARK2	Q05513	PRKCZ	S592	R589L	589	Missense	distal	-3	no	40.240	27.923	EPSD	COSMIC	31.494	Loss
AGC_PKC_PKCi_PRKCZ_ST	Q7KZI7	MARK2	Q05513	PRKCZ	S592	R589W	589	Missense	distal	-3	no	40.240	16.484	EPSD	COSMIC	31.494	Loss
AGC_PKC_PKCi_PRKCZ_ST	Q7KZI7	MARK2	Q05513	PRKCZ	S592	P588L	588	Missense	distal	-4	no	40.240	40.103	EPSD	COSMIC	31.494	Down-regulation
AGC_PKC_PKCi_PRKCZ_ST	Q7KZI7	MARK2	Q05513	PRKCZ	S592	R594H	594	Missense	proximal	2	no	40.240	36.087	EPSD	COSMIC	31.494	Down-regulation
AGC_PKC_PKCi_PRKCZ_ST	Q7KZI7	MARK2	Q05513	PRKCZ	S592	R594L	594	Missense	proximal	2	no	40.240	32.773	EPSD	COSMIC	31.494	Down-regulation
AGC_PKC_PKCi_PRKCZ_ST	Q7KZI7	MARK2	Q05513	PRKCZ	S592	R594C	594	Missense	proximal	2	no	40.240	29.051	EPSD	COSMIC	31.494	Loss
AGC_PKC_PKCi_PRKCZ_ST	Q7KZI7	MARK2	Q05513	PRKCZ	T596	R589H	589	Missense	distal	-7	no	45.293	41.943	PhosphoSitePlus	COSMIC	31.494	Down-regulation
AGC_PKC_PKCi_PRKCZ_ST	Q7KZI7	MARK2	Q05513	PRKCZ	T596	R589L	589	Missense	distal	-7	no	45.293	40.534	PhosphoSitePlus	COSMIC	31.494	Down-regulation
AGC_PKC_PKCi_PRKCZ_ST	Q7KZI7	MARK2	Q05513	PRKCZ	T596	R589W	589	Missense	distal	-7	no	45.293	37.142	PhosphoSitePlus	COSMIC	31.494	Down-regulation
AGC_PKC_PKCi_PRKCZ_ST	Q7KZI7	MARK2	Q05513	PRKCZ	T596	R594H	594	Missense	proximal	-2	no	45.293	36.441	PhosphoSitePlus	COSMIC	31.494	Down-regulation
AGC_PKC_PKCi_PRKCZ_ST	Q7KZI7	MARK2	Q05513	PRKCZ	T596	R603Q	603	Missense	distal	7	no	45.293	43.996	PhosphoSitePlus	COSMIC	31.494	Down-regulation
AGC_PKC_PKCi_PRKCZ_ST	Q7KZI7	MARK2	Q05513	PRKCZ	T596	R594L	594	Missense	proximal	-2	no	45.293	33.734	PhosphoSitePlus	COSMIC	31.494	Down-regulation
AGC_PKC_PKCi_PRKCZ_ST	Q7KZI7	MARK2	Q05513	PRKCZ	T596	R594C	594	Missense	proximal	-2	no	45.293	31.503	PhosphoSitePlus	COSMIC	31.494	Down-regulation
AGC_PKC_PKCi_PRKCZ_ST	Q7KZI7	MARK2	Q05513	PRKCZ	S648	R654Q	654	Missense	distal	6	no	44.027	38.135	EPSD	COSMIC	31.494	Down-regulation
AGC_PKC_PKCi_PRKCZ_ST	Q7KZI7	MARK2	Q05513	PRKCZ	S648	K641R	641	Missense	distal	-7	no	44.027	44.470	EPSD	COSMIC	31.494	Up-regulation
AGC_PKC_PKCi_PRKCZ_ST	Q7KZI7	MARK2	Q05513	PRKCZ	S722	E726K	726	Missense	distal	4	no	33.335	35.002	EPSD	COSMIC	31.494	Up-regulation
AGC_PKC_PKCi_PRKCZ_ST	Q7KZI7	MARK2	Q05513	PRKCZ	S769	R767Q	767	Missense	proximal	-2	no	45.513	35.527	EPSD	COSMIC	31.494	Down-regulation
AGC_PKC_PKCi_PRKCZ_ST	Q7KZI7	MARK2	Q05513	PRKCZ	S769	G762R	762	Missense	distal	-7	no	45.513	50.188	EPSD	COSMIC	31.494	Up-regulation
AGC_PKC_PKCi_PRKCZ_ST	P10636	MAPT	Q05513	PRKCZ	S64	E62K	62	Missense	proximal	-2	no	26.472	36.366	EPSD	COSMIC	31.494	Gain
AGC_PKC_PKCi_PRKCZ_ST	P10636	MAPT	Q05513	PRKCZ	T167	E165K	165	Missense	proximal	-2	no	25.159	35.053	EPSD	COSMIC	31.494	Gain
AGC_PKC_PKCi_PRKCZ_ST	P10636	MAPT	Q05513	PRKCZ	S171	P175S	175	Missense	distal	4	no	39.858	46.895	EPSD	COSMIC	31.494	Up-regulation
AGC_PKC_PKCi_PRKCZ_ST	P10636	MAPT	Q05513	PRKCZ	S171	A166V	166	Missense	distal	-5	no	39.858	42.446	EPSD	COSMIC;CCLE	31.494	Up-regulation
AGC_PKC_PKCi_PRKCZ_ST	P10636	MAPT	Q05513	PRKCZ	S171	E176G	176	Missense	distal	5	no	39.858	40.047	EPSD	COSMIC	31.494	Up-regulation
AGC_PKC_PKCi_PRKCZ_ST	P10636	MAPT	Q05513	PRKCZ	S171	D177G	177	Missense	distal	6	no	39.858	35.821	EPSD	COSMIC	31.494	Down-regulation
AGC_PKC_PKCi_PRKCZ_ST	P10636	MAPT	Q05513	PRKCZ	S171	E165K	165	Missense	distal	-6	no	39.858	39.416	EPSD	COSMIC	31.494	Down-regulation
AGC_PKC_PKCi_PRKCZ_ST	P10636	MAPT	Q05513	PRKCZ	S171	G172V	172	Missense	proximal	1	no	39.858	40.599	EPSD	COSMIC	31.494	Up-regulation
AGC_PKC_PKCi_PRKCZ_ST	P10636	MAPT	Q05513	PRKCZ	S228	E226K	226	Missense	proximal	-2	no	23.957	33.851	EPSD	COSMIC	31.494	Gain
AGC_PKC_PKCi_PRKCZ_ST	P10636	MAPT	Q05513	PRKCZ	S228	Q230R	230	Missense	proximal	2	no	23.957	31.826	EPSD	COSMIC	31.494	Gain
AGC_PKC_PKCi_PRKCZ_ST	P10636	MAPT	Q05513	PRKCZ	S238	D242N	242	Missense	distal	4	no	29.331	35.278	EPSD	COSMIC	31.494	Gain
AGC_PKC_PKCi_PRKCZ_ST	P10636	MAPT	Q05513	PRKCZ	S341	A337T	337	Missense	distal	-4	no	32.156	32.203	EPSD	COSMIC	31.494	Up-regulation
AGC_PKC_PKCi_PRKCZ_ST	P10636	MAPT	Q05513	PRKCZ	S341	G343R	343	Missense	proximal	2	no	32.156	41.315	EPSD	COSMIC	31.494	Up-regulation
AGC_PKC_PKCi_PRKCZ_ST	P10636	MAPT	Q05513	PRKCZ	S341	D345G	345	Missense	distal	4	no	32.156	33.684	EPSD	COSMIC	31.494	Up-regulation
AGC_PKC_PKCi_PRKCZ_ST	P10636	MAPT	Q05513	PRKCZ	S341	K347N	347	Missense	distal	6	no	32.156	31.653	EPSD	COSMIC	31.494	Down-regulation
AGC_PKC_PKCi_PRKCZ_ST	P10636	MAPT	Q05513	PRKCZ	S388	G385V	385	Missense	distal	-3	no	31.313	33.933	EPSD	COSMIC	31.494	Gain
AGC_PKC_PKCi_PRKCZ_ST	P10636	MAPT	Q05513	PRKCZ	S388	D389N	389	Missense	proximal	1	no	31.313	31.514	EPSD	COSMIC;GDSC;CCLE	31.494	Gain
AGC_PKC_PKCi_PRKCZ_ST	P10636	MAPT	Q05513	PRKCZ	S400	R398C	398	Missense	proximal	-2	no	38.197	24.406	EPSD	COSMIC	31.494	Loss
AGC_PKC_PKCi_PRKCZ_ST	P10636	MAPT	Q05513	PRKCZ	S400	S396F	396	Missense	distal	-4	no	38.197	38.309	EPSD	COSMIC	31.494	Up-regulation
AGC_PKC_PKCi_PRKCZ_ST	P10636	MAPT	Q05513	PRKCZ	S447	S443Y	443	Missense	distal	-4	no	43.476	43.504	EPSD	COSMIC	31.494	Up-regulation
AGC_PKC_PKCi_PRKCZ_ST	P10636	MAPT	Q05513	PRKCZ	S447	S447P	447	Missense	central	0	yes	43.476	0.000	EPSD	COSMIC	31.494	Loss
AGC_PKC_PKCi_PRKCZ_ST	P10636	MAPT	Q05513	PRKCZ	S447	R448Q	448	Missense	proximal	1	no	43.476	41.202	EPSD	COSMIC	31.494	Down-regulation
AGC_PKC_PKCi_PRKCZ_ST	P10636	MAPT	Q05513	PRKCZ	S554	P550S	550	Missense	distal	-4	no	36.742	36.344	EPSD	COSMIC	31.494	Down-regulation
AGC_PKC_PKCi_PRKCZ_ST	P10636	MAPT	Q05513	PRKCZ	S554	R559C	559	Missense	distal	5	no	36.742	36.036	EPSD	COSMIC	31.494	Down-regulation
AGC_PKC_PKCi_PRKCZ_ST	P10636	MAPT	Q05513	PRKCZ	S554	P553R	553	Missense	proximal	-1	no	36.742	38.700	EPSD	COSMIC	31.494	Up-regulation
AGC_PKC_PKCi_PRKCZ_ST	P10636	MAPT	Q05513	PRKCZ	S554	P553L	553	Missense	proximal	-1	no	36.742	36.903	EPSD	COSMIC	31.494	Up-regulation
AGC_PKC_PKCi_PRKCZ_ST	P10636	MAPT	Q05513	PRKCZ	S554	P549L	549	Missense	distal	-5	no	36.742	36.866	EPSD	COSMIC	31.494	Up-regulation
AGC_PKC_PKCi_PRKCZ_ST	P10636	MAPT	Q05513	PRKCZ	S554	S555F	555	Missense	proximal	1	no	36.742	37.993	EPSD	COSMIC	31.494	Up-regulation
AGC_PKC_PKCi_PRKCZ_ST	P10636	MAPT	Q05513	PRKCZ	S554	P553Q	553	Missense	proximal	-1	no	36.742	37.538	EPSD	COSMIC	31.494	Up-regulation
AGC_PKC_PKCi_PRKCZ_ST	P10636	MAPT	Q05513	PRKCZ	S602	S602G	602	Missense	central	0	yes	32.017	0.000	EPSD	COSMIC	31.494	Loss
AGC_PKC_PKCi_PRKCZ_ST	P10636	MAPT	Q05513	PRKCZ	S602	I595L	595	Missense	distal	-7	no	32.017	34.713	EPSD	COSMIC	31.494	Up-regulation
AGC_PKC_PKCi_PRKCZ_ST	P10636	MAPT	Q05513	PRKCZ	S602	K598T	598	Missense	distal	-4	no	32.017	32.028	EPSD	COSMIC	31.494	Up-regulation
AGC_PKC_PKCi_PRKCZ_ST	P10636	MAPT	Q05513	PRKCZ	S602	C608W	608	Missense	distal	6	no	32.017	31.293	EPSD	COSMIC	31.494	Loss
AGC_PKC_PKCi_PRKCZ_ST	P10636	MAPT	Q05513	PRKCZ	S602	D600E	600	Missense	proximal	-2	no	32.017	23.610	EPSD	COSMIC	31.494	Loss
AGC_PKC_PKCi_PRKCZ_ST	P10636	MAPT	Q05513	PRKCZ	S633	S633N	633	Missense	central	0	yes	31.601	0.000	EPSD	COSMIC	31.494	Loss
AGC_PKC_PKCi_PRKCZ_ST	P10636	MAPT	Q05513	PRKCZ	S633	S633I	633	Missense	central	0	yes	31.601	0.000	EPSD	COSMIC	31.494	Loss
AGC_PKC_PKCi_PRKCZ_ST	P10636	MAPT	Q05513	PRKCZ	S658	D662G	662	Missense	distal	4	no	33.800	35.328	EPSD	COSMIC	31.494	Up-regulation
AGC_PKC_PKCi_PRKCZ_ST	P10636	MAPT	Q05513	PRKCZ	S658	K664N	664	Missense	distal	6	no	33.800	33.297	EPSD	COSMIC	31.494	Down-regulation
AGC_PKC_PKCi_PRKCZ_ST	P10636	MAPT	Q05513	PRKCZ	S669	S669L	669	Missense	central	0	yes	39.132	0.000	EPSD	COSMIC	31.494	Loss
AGC_PKC_PKCi_PRKCZ_ST	P10636	MAPT	Q05513	PRKCZ	S669	R666K	666	Missense	distal	-3	no	39.132	33.994	EPSD	COSMIC	31.494	Down-regulation
AGC_PKC_PKCi_PRKCZ_ST	P10636	MAPT	Q05513	PRKCZ	S669	D662G	662	Missense	distal	-7	no	39.132	36.997	EPSD	COSMIC	31.494	Down-regulation
AGC_PKC_PKCi_PRKCZ_ST	P10636	MAPT	Q05513	PRKCZ	S669	S673F	673	Missense	distal	4	no	39.132	26.916	EPSD	COSMIC	31.494	Loss
AGC_PKC_PKCi_PRKCZ_ST	P10636	MAPT	Q05513	PRKCZ	S669	K670N	670	Missense	proximal	1	no	39.132	38.864	EPSD	COSMIC	31.494	Down-regulation
AGC_PKC_PKCi_PRKCZ_ST	P10636	MAPT	Q05513	PRKCZ	S669	K664N	664	Missense	distal	-5	no	39.132	38.159	EPSD	COSMIC	31.494	Down-regulation
AGC_PKC_PKCi_PRKCZ_ST	P10636	MAPT	Q05513	PRKCZ	S669	L674Q	674	Missense	distal	5	no	39.132	39.157	EPSD	COSMIC	31.494	Up-regulation
AGC_PKC_PKCi_PRKCZ_ST	P10636	MAPT	Q05513	PRKCZ	T690	R696H	696	Missense	distal	6	no	32.767	31.724	EPSD	COSMIC	31.494	Down-regulation
AGC_PKC_PKCi_PRKCZ_ST	P10636	MAPT	Q05513	PRKCZ	T690	G683R	683	Missense	distal	-7	no	32.767	37.441	EPSD	COSMIC;CCLE	31.494	Up-regulation
AGC_PKC_PKCi_PRKCZ_ST	P10636	MAPT	Q05513	PRKCZ	T690	G683E	683	Missense	distal	-7	no	32.767	31.178	EPSD	COSMIC	31.494	Loss
AGC_PKC_PKCi_PRKCZ_ST	P10636	MAPT	Q05513	PRKCZ	T690	R696C	696	Missense	distal	6	no	32.767	25.756	EPSD	COSMIC	31.494	Loss
AGC_PKC_PKCi_PRKCZ_ST	P10636	MAPT	Q05513	PRKCZ	T690	G684E	684	Missense	distal	-6	no	32.767	32.973	EPSD	COSMIC	31.494	Up-regulation
AGC_PKC_PKCi_PRKCZ_ST	P10636	MAPT	Q05513	PRKCZ	T694	R696H	696	Missense	proximal	2	no	36.945	32.791	EPSD	COSMIC	31.494	Down-regulation
AGC_PKC_PKCi_PRKCZ_ST	P10636	MAPT	Q05513	PRKCZ	T694	R696C	696	Missense	proximal	2	no	36.945	25.756	EPSD	COSMIC	31.494	Loss
AGC_PKC_PKCi_PRKCZ_ST	P10636	MAPT	Q05513	PRKCZ	T703	R696H	696	Missense	distal	-7	no	38.159	34.809	EPSD	COSMIC	31.494	Down-regulation
AGC_PKC_PKCi_PRKCZ_ST	P10636	MAPT	Q05513	PRKCZ	T703	E708D	708	Missense	distal	5	no	38.159	38.476	EPSD	COSMIC	31.494	Up-regulation
AGC_PKC_PKCi_PRKCZ_ST	P10636	MAPT	Q05513	PRKCZ	T703	G706R	706	Missense	distal	3	no	38.159	41.682	EPSD	COSMIC	31.494	Up-regulation
AGC_PKC_PKCi_PRKCZ_ST	P10636	MAPT	Q05513	PRKCZ	T703	V710M	710	Missense	distal	7	no	38.159	37.794	EPSD	COSMIC	31.494	Down-regulation
AGC_PKC_PKCi_PRKCZ_ST	P10636	MAPT	Q05513	PRKCZ	T703	E708K	708	Missense	distal	5	no	38.159	38.421	EPSD	COSMIC	31.494	Up-regulation
AGC_PKC_PKCi_PRKCZ_ST	P10636	MAPT	Q05513	PRKCZ	T703	R696C	696	Missense	distal	-7	no	38.159	32.325	EPSD	COSMIC	31.494	Down-regulation
AGC_PKC_PKCi_PRKCZ_ST	P10636	MAPT	Q05513	PRKCZ	T703	V710A	710	Missense	distal	7	no	38.159	38.412	EPSD	COSMIC	31.494	Up-regulation
AGC_PKC_PKCi_PRKCZ_ST	P10636	MAPT	Q05513	PRKCZ	T703	T703I	703	Missense	central	0	yes	38.159	0.000	EPSD	COSMIC	31.494	Loss
AGC_PKC_PKCi_PRKCZ_ST	P10636	MAPT	Q05513	PRKCZ	T744	E748K	748	Missense	distal	4	no	31.521	33.188	EPSD	COSMIC	31.494	Up-regulation
AGC_PKC_PKCi_PRKCZ_ST	P10636	MAPT	Q05513	PRKCZ	T744	T744M	744	Missense	central	0	yes	31.521	0.000	EPSD	COSMIC	31.494	Loss
AGC_PKC_PKCi_PRKCZ_ST	P10636	MAPT	Q05513	PRKCZ	T744	A743T	743	Missense	proximal	-1	no	31.521	30.573	EPSD	COSMIC	31.494	Loss
AGC_PKC_PKCi_PRKCZ_ST	P10636	MAPT	Q05513	PRKCZ	S750	E748K	748	Missense	proximal	-2	no	46.562	56.456	EPSD	COSMIC	31.494	Up-regulation
AGC_PKC_PKCi_PRKCZ_ST	P10636	MAPT	Q05513	PRKCZ	S750	T744M	744	Missense	distal	-6	no	46.562	46.522	EPSD	COSMIC	31.494	Down-regulation
AGC_PKC_PKCi_PRKCZ_ST	P10636	MAPT	Q05513	PRKCZ	S750	A743T	743	Missense	distal	-7	no	46.562	44.433	EPSD	COSMIC	31.494	Down-regulation
AGC_PKC_PKCi_PRKCZ_ST	P10636	MAPT	Q05513	PRKCZ	S752	E748K	748	Missense	distal	-4	no	42.896	42.567	EPSD	COSMIC	31.494	Down-regulation
AGC_PKC_PKCi_PRKCZ_ST	P61587	RND3	Q05513	PRKCZ	S7	L10V	10	Missense	distal	3	no	56.159	51.992	EPSD	COSMIC	31.494	Down-regulation
AGC_PKC_PKCi_PRKCZ_ST	P61587	RND3	Q05513	PRKCZ	S11	L10V	10	Missense	proximal	-1	no	40.007	40.471	EPSD	COSMIC	31.494	Up-regulation
AGC_PKC_PKCi_PRKCZ_ST	P61587	RND3	Q05513	PRKCZ	S12	L10V	10	Missense	proximal	-2	no	39.179	37.925	EPSD	COSMIC	31.494	Down-regulation
AGC_PKC_PKCi_PRKCZ_ST	P61587	RND3	Q05513	PRKCZ	S210	A213P	213	Missense	distal	3	no	58.835	45.761	PhosphoSitePlus	COSMIC	31.494	Down-regulation
AGC_PKC_PKCi_PRKCZ_ST	P61587	RND3	Q05513	PRKCZ	S210	N204S	204	Missense	distal	-6	no	58.835	58.828	PhosphoSitePlus	COSMIC	31.494	Down-regulation
AGC_PKC_PKCi_PRKCZ_ST	P61587	RND3	Q05513	PRKCZ	S210	A213V	213	Missense	distal	3	no	58.835	49.442	PhosphoSitePlus	COSMIC	31.494	Down-regulation
AGC_PKC_PKCi_PRKCZ_ST	P61587	RND3	Q05513	PRKCZ	S210	R207W	207	Missense	distal	-3	no	58.835	35.079	PhosphoSitePlus	COSMIC	31.494	Down-regulation
AGC_PKC_PKCi_PRKCZ_ST	P61587	RND3	Q05513	PRKCZ	S240	S240I	240	Missense	central	0	yes	36.968	0.000	EPSD	COSMIC	31.494	Loss
AGC_PKC_PKCi_PRKCZ_ST	O43175	PHGDH	Q05513	PRKCZ	S55	C48R	48	Missense	distal	-7	no	27.158	32.992	PhosphoSitePlus;EPSD	COSMIC	31.494	Gain
AGC_PKC_PKCi_PRKCZ_ST	O43175	PHGDH	Q05513	PRKCZ	T57	D62H	62	Missense	distal	5	no	36.729	36.629	EPSD;PhosphoSitePlus	COSMIC	31.494	Down-regulation
AGC_PKC_PKCi_PRKCZ_ST	O43175	PHGDH	Q05513	PRKCZ	T57	G50C	50	Missense	distal	-7	no	36.729	35.569	EPSD;PhosphoSitePlus	COSMIC;GDSC;CCLE	31.494	Down-regulation
AGC_PKC_PKCi_PRKCZ_ST	O43175	PHGDH	Q05513	PRKCZ	T57	R54S	54	Missense	distal	-3	no	36.729	23.303	EPSD;PhosphoSitePlus	COSMIC	31.494	Loss
AGC_PKC_PKCi_PRKCZ_ST	O43175	PHGDH	Q05513	PRKCZ	S166	S166F	166	Missense	central	0	yes	34.088	0.000	EPSD	COSMIC	31.494	Loss
AGC_PKC_PKCi_PRKCZ_ST	O43175	PHGDH	Q05513	PRKCZ	S362	C369R	369	Missense	distal	7	no	39.610	36.348	EPSD	COSMIC	31.494	Down-regulation
AGC_PKC_PKCi_PRKCZ_ST	P53004	BLVRA	Q05513	PRKCZ	S21	S21F	21	Missense	central	0	yes	38.923	0.000	EPSD	COSMIC	31.494	Loss
AGC_PKC_PKCi_PRKCZ_ST	P53004	BLVRA	Q05513	PRKCZ	S237	E239D	239	Missense	proximal	2	no	28.243	36.443	EPSD	COSMIC	31.494	Gain
AGC_PKC_PKCi_PRKCZ_ST	Q13118	KLF10	Q05513	PRKCZ	S184	L178I	178	Missense	distal	-6	no	36.025	36.132	EPSD	COSMIC	31.494	Up-regulation
AGC_PKC_PKCi_PRKCZ_ST	Q13118	KLF10	Q05513	PRKCZ	S184	R187K	187	Missense	distal	3	no	36.025	35.297	EPSD	COSMIC	31.494	Down-regulation
AGC_PKC_PKCi_PRKCZ_ST	Q13118	KLF10	Q05513	PRKCZ	S249	S249F	249	Missense	central	0	yes	31.583	0.000	EPSD	COSMIC	31.494	Loss
AGC_PKC_PKCi_PRKCZ_ST	Q13118	KLF10	Q05513	PRKCZ	S249	P247S	247	Missense	proximal	-2	no	31.583	33.429	EPSD	COSMIC	31.494	Up-regulation
AGC_PKC_PKCi_PRKCZ_ST	Q13118	KLF10	Q05513	PRKCZ	T422	G425D	425	Missense	distal	3	no	33.343	31.829	EPSD	COSMIC;GDSC;CCLE	31.494	Down-regulation
AGC_PKC_PKCi_PRKCZ_ST	Q13118	KLF10	Q05513	PRKCZ	T422	T424K	424	Missense	proximal	2	no	33.343	39.738	EPSD	COSMIC	31.494	Up-regulation
AGC_PKC_PKCi_PRKCZ_ST	Q13118	KLF10	Q05513	PRKCZ	T424	G425D	425	Missense	proximal	1	no	38.059	37.655	EPSD	COSMIC;GDSC;CCLE	31.494	Down-regulation
AGC_PKC_PKCi_PRKCZ_ST	Q13118	KLF10	Q05513	PRKCZ	T424	T424K	424	Missense	central	0	yes	38.059	0.000	EPSD	COSMIC	31.494	Loss
AGC_PKC_PKCi_PRKCZ_ST	P49841	GSK3B	Q05513	PRKCZ	S9	S9F	9	Missense	central	0	yes	36.187	0.000	EPSD;PhosphoSitePlus	COSMIC	31.494	Loss
AGC_PKC_PKCi_PRKCZ_ST	P49841	GSK3B	Q05513	PRKCZ	S9	P16A	16	Missense	distal	7	no	36.187	33.276	EPSD;PhosphoSitePlus	COSMIC	31.494	Down-regulation
AGC_PKC_PKCi_PRKCZ_ST	P49841	GSK3B	Q05513	PRKCZ	S9	S2P	2	Missense	distal	-7	no	36.187	34.344	EPSD;PhosphoSitePlus	COSMIC	31.494	Down-regulation
AGC_PKC_PKCi_PRKCZ_ST	P49841	GSK3B	Q05513	PRKCZ	S13	P16A	16	Missense	distal	3	no	20.440	33.514	EPSD	COSMIC	31.494	Gain
AGC_PKC_PKCi_PRKCZ_ST	P49841	GSK3B	Q05513	PRKCZ	S29	D31Y	31	Missense	proximal	2	no	40.769	34.701	EPSD	COSMIC	31.494	Down-regulation
AGC_PKC_PKCi_PRKCZ_ST	P49841	GSK3B	Q05513	PRKCZ	S29	S25C	25	Missense	distal	-4	no	40.769	41.131	EPSD	COSMIC	31.494	Up-regulation
AGC_PKC_PKCi_PRKCZ_ST	P49841	GSK3B	Q05513	PRKCZ	S29	D33N	33	Missense	distal	4	no	40.769	46.716	EPSD	COSMIC	31.494	Up-regulation
AGC_PKC_PKCi_PRKCZ_ST	P49841	GSK3B	Q05513	PRKCZ	S29	S35R	35	Missense	distal	6	no	40.769	45.182	EPSD	COSMIC	31.494	Up-regulation
AGC_PKC_PKCi_PRKCZ_ST	P49841	GSK3B	Q05513	PRKCZ	S29	D33G	33	Missense	distal	4	no	40.769	42.298	EPSD	COSMIC;GDSC;CCLE	31.494	Up-regulation
AGC_PKC_PKCi_PRKCZ_ST	P49841	GSK3B	Q05513	PRKCZ	S29	D33H	33	Missense	distal	4	no	40.769	43.350	EPSD	COSMIC	31.494	Up-regulation
AGC_PKC_PKCi_PRKCZ_ST	P49841	GSK3B	Q05513	PRKCZ	S29	A22T	22	Missense	distal	-7	no	40.769	38.640	EPSD	COSMIC	31.494	Down-regulation
AGC_PKC_PKCi_PRKCZ_ST	P49841	GSK3B	Q05513	PRKCZ	S147	P154S	154	Missense	distal	7	no	42.594	39.285	PhosphoSitePlus;EPSD	COSMIC	31.494	Down-regulation
AGC_PKC_PKCi_PRKCZ_ST	P49841	GSK3B	Q05513	PRKCZ	S147	Y146C	146	Missense	proximal	-1	no	42.594	42.559	PhosphoSitePlus;EPSD	COSMIC	31.494	Down-regulation
AGC_PKC_PKCi_PRKCZ_ST	P49841	GSK3B	Q05513	PRKCZ	S147	R148Q	148	Missense	proximal	1	no	42.594	40.321	PhosphoSitePlus;EPSD	COSMIC	31.494	Down-regulation
AGC_PKC_PKCi_PRKCZ_ST	P49841	GSK3B	Q05513	PRKCZ	S147	S147N	147	Missense	central	0	yes	42.594	0.000	PhosphoSitePlus;EPSD	COSMIC	31.494	Loss
AGC_PKC_PKCi_PRKCZ_ST	P49841	GSK3B	Q05513	PRKCZ	S147	Y140C	140	Missense	distal	-7	no	42.594	41.885	PhosphoSitePlus;EPSD	COSMIC	31.494	Down-regulation
AGC_PKC_PKCi_PRKCZ_ST	P49841	GSK3B	Q05513	PRKCZ	S147	A143G	143	Missense	distal	-4	no	42.594	42.769	PhosphoSitePlus;EPSD	COSMIC	31.494	Up-regulation
AGC_PKC_PKCi_PRKCZ_ST	P49841	GSK3B	Q05513	PRKCZ	S147	R141S	141	Missense	distal	-6	no	42.594	43.067	PhosphoSitePlus;EPSD	COSMIC	31.494	Up-regulation
AGC_PKC_PKCi_PRKCZ_ST	P49841	GSK3B	Q05513	PRKCZ	S203	Q206K	206	Missense	distal	3	no	32.200	37.069	EPSD	COSMIC	31.494	Up-regulation
AGC_PKC_PKCi_PRKCZ_ST	P49841	GSK3B	Q05513	PRKCZ	S203	L196V	196	Missense	distal	-7	no	32.200	30.791	EPSD	COSMIC	31.494	Loss
AGC_PKC_PKCi_PRKCZ_ST	P49841	GSK3B	Q05513	PRKCZ	T402	A397V	397	Missense	distal	-5	no	29.529	32.117	EPSD	COSMIC;CCLE	31.494	Gain
AGC_PKC_PKCi_PRKCZ_ST	P49841	GSK3B	Q05513	PRKCZ	T408	R405S	405	Missense	distal	-3	no	47.037	33.611	EPSD	COSMIC	31.494	Down-regulation
AGC_PKC_PKCi_PRKCZ_ST	P49841	GSK3B	Q05513	PRKCZ	T408	T402I	402	Missense	distal	-6	no	47.037	47.268	EPSD	COSMIC	31.494	Up-regulation
AGC_PKC_PKCi_PRKCZ_ST	P49841	GSK3B	Q05513	PRKCZ	T408	R405H	405	Missense	distal	-3	no	47.037	38.608	EPSD	COSMIC;CCLE	31.494	Down-regulation
AGC_PKC_PKCi_PRKCZ_ST	P49757	NUMB	Q05513	PRKCZ	S7	R5W	5	Missense	proximal	-2	no	59.036	40.862	PhosphoSitePlus;EPSD	COSMIC	31.494	Down-regulation
AGC_PKC_PKCi_PRKCZ_ST	P49757	NUMB	Q05513	PRKCZ	S7	L4V	4	Missense	distal	-3	no	59.036	59.735	PhosphoSitePlus;EPSD	COSMIC	31.494	Up-regulation
AGC_PKC_PKCi_PRKCZ_ST	P49757	NUMB	Q05513	PRKCZ	S7	S7N	7	Missense	central	0	yes	59.036	0.000	PhosphoSitePlus;EPSD	COSMIC	31.494	Loss
AGC_PKC_PKCi_PRKCZ_ST	P49757	NUMB	Q05513	PRKCZ	S276	P281S	281	Missense	distal	5	no	32.914	32.893	EPSD	COSMIC	31.494	Down-regulation
AGC_PKC_PKCi_PRKCZ_ST	P49757	NUMB	Q05513	PRKCZ	S276	P281H	281	Missense	distal	5	no	32.914	33.070	EPSD	COSMIC	31.494	Up-regulation
AGC_PKC_PKCi_PRKCZ_ST	P49757	NUMB	Q05513	PRKCZ	S276	G275D	275	Missense	proximal	-1	no	32.914	32.396	EPSD	COSMIC	31.494	Down-regulation
AGC_PKC_PKCi_PRKCZ_ST	P49757	NUMB	Q05513	PRKCZ	S276	R278P	278	Missense	proximal	2	no	32.914	20.370	EPSD	COSMIC	31.494	Loss
AGC_PKC_PKCi_PRKCZ_ST	P49757	NUMB	Q05513	PRKCZ	S295	P302S	302	Missense	distal	7	no	34.788	31.480	EPSD	COSMIC	31.494	Loss
AGC_PKC_PKCi_PRKCZ_ST	P49757	NUMB	Q05513	PRKCZ	S295	R297G	297	Missense	proximal	2	no	34.788	25.629	EPSD	COSMIC	31.494	Loss
AGC_PKC_PKCi_PRKCZ_ST	P49757	NUMB	Q05513	PRKCZ	S295	R297S	297	Missense	proximal	2	no	34.788	24.762	EPSD	COSMIC	31.494	Loss
AGC_PKC_PKCi_PRKCZ_ST	P49757	NUMB	Q05513	PRKCZ	T304	R307W	307	Missense	distal	3	no	32.742	17.946	EPSD	COSMIC	31.494	Loss
AGC_PKC_PKCi_PRKCZ_ST	P49757	NUMB	Q05513	PRKCZ	T304	P302S	302	Missense	proximal	-2	no	32.742	34.588	EPSD	COSMIC	31.494	Up-regulation
AGC_PKC_PKCi_PRKCZ_ST	P49757	NUMB	Q05513	PRKCZ	T304	R297G	297	Missense	distal	-7	no	32.742	28.068	EPSD	COSMIC	31.494	Loss
AGC_PKC_PKCi_PRKCZ_ST	P49757	NUMB	Q05513	PRKCZ	T304	R297S	297	Missense	distal	-7	no	32.742	27.591	EPSD	COSMIC	31.494	Loss
AGC_PKC_PKCi_PRKCZ_ST	Q15831	STK11	Q05513	PRKCZ	S299	Q302P	302	Missense	distal	3	no	45.940	35.469	EPSD	COSMIC;CCLE	31.494	Down-regulation
AGC_PKC_PKCi_PRKCZ_ST	Q15831	STK11	Q05513	PRKCZ	S299	F298L	298	Missense	proximal	-1	no	45.940	45.927	EPSD	COSMIC	31.494	Down-regulation
AGC_PKC_PKCi_PRKCZ_ST	Q15831	STK11	Q05513	PRKCZ	S299	R297K	297	Missense	proximal	-2	no	45.940	40.714	EPSD	COSMIC	31.494	Down-regulation
AGC_PKC_PKCi_PRKCZ_ST	Q15831	STK11	Q05513	PRKCZ	S299	S299F	299	Missense	central	0	yes	45.940	0.000	EPSD	COSMIC;CCLE	31.494	Loss
AGC_PKC_PKCi_PRKCZ_ST	Q15831	STK11	Q05513	PRKCZ	S299	Y292D	292	Missense	distal	-7	no	45.940	48.525	EPSD	COSMIC	31.494	Up-regulation
AGC_PKC_PKCi_PRKCZ_ST	Q15831	STK11	Q05513	PRKCZ	S299	R304G	304	Missense	distal	5	no	45.940	45.501	EPSD	COSMIC	31.494	Down-regulation
AGC_PKC_PKCi_PRKCZ_ST	Q15831	STK11	Q05513	PRKCZ	S299	I303M	303	Missense	distal	4	no	45.940	50.035	EPSD	COSMIC	31.494	Up-regulation
AGC_PKC_PKCi_PRKCZ_ST	Q15831	STK11	Q05513	PRKCZ	S299	Q302H	302	Missense	distal	3	no	45.940	45.308	EPSD	COSMIC	31.494	Down-regulation
AGC_PKC_PKCi_PRKCZ_ST	Q15831	STK11	Q05513	PRKCZ	S299	I303F	303	Missense	distal	4	no	45.940	40.844	EPSD	COSMIC	31.494	Down-regulation
AGC_PKC_PKCi_PRKCZ_ST	Q15831	STK11	Q05513	PRKCZ	S299	P294S	294	Missense	distal	-5	no	45.940	44.548	EPSD	COSMIC	31.494	Down-regulation
AGC_PKC_PKCi_PRKCZ_ST	Q15831	STK11	Q05513	PRKCZ	S299	I303S	303	Missense	distal	4	no	45.940	53.060	EPSD	COSMIC	31.494	Up-regulation
AGC_PKC_PKCi_PRKCZ_ST	Q15831	STK11	Q05513	PRKCZ	S307	Q302P	302	Missense	distal	-5	no	48.975	49.995	EPSD;PhosphoSitePlus	COSMIC;CCLE	31.494	Up-regulation
AGC_PKC_PKCi_PRKCZ_ST	Q15831	STK11	Q05513	PRKCZ	S307	P314H	314	Missense	distal	7	no	48.975	45.170	EPSD;PhosphoSitePlus	COSMIC	31.494	Down-regulation
AGC_PKC_PKCi_PRKCZ_ST	Q15831	STK11	Q05513	PRKCZ	S307	R304G	304	Missense	distal	-3	no	48.975	34.738	EPSD;PhosphoSitePlus	COSMIC	31.494	Down-regulation
AGC_PKC_PKCi_PRKCZ_ST	Q15831	STK11	Q05513	PRKCZ	S307	R310Q	310	Missense	distal	3	no	48.975	43.378	EPSD;PhosphoSitePlus	COSMIC	31.494	Down-regulation
AGC_PKC_PKCi_PRKCZ_ST	Q15831	STK11	Q05513	PRKCZ	S307	I303M	303	Missense	distal	-4	no	48.975	48.674	EPSD;PhosphoSitePlus	COSMIC	31.494	Down-regulation
AGC_PKC_PKCi_PRKCZ_ST	Q15831	STK11	Q05513	PRKCZ	S307	W308C	308	Missense	proximal	1	no	48.975	50.160	EPSD;PhosphoSitePlus	COSMIC	31.494	Up-regulation
AGC_PKC_PKCi_PRKCZ_ST	Q15831	STK11	Q05513	PRKCZ	S307	Q302H	302	Missense	distal	-5	no	48.975	47.938	EPSD;PhosphoSitePlus	COSMIC	31.494	Down-regulation
AGC_PKC_PKCi_PRKCZ_ST	Q15831	STK11	Q05513	PRKCZ	S307	H313N	313	Missense	distal	6	no	48.975	46.237	EPSD;PhosphoSitePlus	COSMIC	31.494	Down-regulation
AGC_PKC_PKCi_PRKCZ_ST	Q15831	STK11	Q05513	PRKCZ	S307	I303F	303	Missense	distal	-4	no	48.975	49.008	EPSD;PhosphoSitePlus	COSMIC	31.494	Up-regulation
AGC_PKC_PKCi_PRKCZ_ST	Q15831	STK11	Q05513	PRKCZ	S307	I303S	303	Missense	distal	-4	no	48.975	48.895	EPSD;PhosphoSitePlus	COSMIC	31.494	Down-regulation
AGC_PKC_PKCi_PRKCZ_ST	Q15831	STK11	Q05513	PRKCZ	S325	P324R	324	Missense	proximal	-1	no	31.255	33.213	EPSD	COSMIC	31.494	Gain
AGC_PKC_PKCi_PRKCZ_ST	Q15831	STK11	Q05513	PRKCZ	S334	W332R	332	Missense	proximal	-2	no	16.034	34.208	EPSD	COSMIC	31.494	Gain
AGC_PKC_PKCi_PRKCZ_ST	Q15831	STK11	Q05513	PRKCZ	T336	W332R	332	Missense	distal	-4	no	42.436	41.716	EPSD	COSMIC	31.494	Down-regulation
AGC_PKC_PKCi_PRKCZ_ST	Q15831	STK11	Q05513	PRKCZ	T336	M335T	335	Missense	proximal	-1	no	42.436	41.862	EPSD	COSMIC	31.494	Down-regulation
AGC_PKC_PKCi_PRKCZ_ST	Q15831	STK11	Q05513	PRKCZ	T336	M335I	335	Missense	proximal	-1	no	42.436	41.635	EPSD	COSMIC	31.494	Down-regulation
AGC_PKC_PKCi_PRKCZ_ST	Q15831	STK11	Q05513	PRKCZ	T336	R333H	333	Missense	distal	-3	no	42.436	34.007	EPSD	COSMIC	31.494	Down-regulation
AGC_PKC_PKCi_PRKCZ_ST	Q15831	STK11	Q05513	PRKCZ	T336	R331Q	331	Missense	distal	-5	no	42.436	44.847	EPSD	COSMIC	31.494	Up-regulation
AGC_PKC_PKCi_PRKCZ_ST	Q15831	STK11	Q05513	PRKCZ	S404	K403I	403	Missense	proximal	-1	no	33.539	32.453	EPSD	COSMIC;CCLE	31.494	Down-regulation
AGC_PKC_PKCi_PRKCZ_ST	Q15831	STK11	Q05513	PRKCZ	S404	A398V	398	Missense	distal	-6	no	33.539	33.902	EPSD	COSMIC	31.494	Up-regulation
AGC_PKC_PKCi_PRKCZ_ST	Q15831	STK11	Q05513	PRKCZ	S404	A397V	397	Missense	distal	-7	no	33.539	29.596	EPSD	COSMIC	31.494	Loss
AGC_PKC_PKCi_PRKCZ_ST	Q15831	STK11	Q05513	PRKCZ	S404	T402A	402	Missense	proximal	-2	no	33.539	34.708	EPSD	COSMIC	31.494	Up-regulation
AGC_PKC_PKCi_PRKCZ_ST	Q15831	STK11	Q05513	PRKCZ	S404	Q399P	399	Missense	distal	-5	no	33.539	34.558	EPSD	COSMIC	31.494	Up-regulation
AGC_PKC_PKCi_PRKCZ_ST	Q15831	STK11	Q05513	PRKCZ	S404	R409Q	409	Missense	distal	5	no	33.539	32.912	EPSD	COSMIC	31.494	Down-regulation
AGC_PKC_PKCi_PRKCZ_ST	Q15831	STK11	Q05513	PRKCZ	S404	R409W	409	Missense	distal	5	no	33.539	32.712	EPSD	COSMIC	31.494	Down-regulation
AGC_PKC_PKCi_PRKCZ_ST	Q15831	STK11	Q05513	PRKCZ	S428	R425W	425	Missense	distal	-3	no	55.503	31.747	EPSD;PhosphoSitePlus	COSMIC	31.494	Down-regulation
AGC_PKC_PKCi_PRKCZ_ST	Q15831	STK11	Q05513	PRKCZ	S428	S428L	428	Missense	central	0	yes	55.503	0.000	EPSD;PhosphoSitePlus	COSMIC	31.494	Loss
AGC_PKC_PKCi_PRKCZ_ST	Q15831	STK11	Q05513	PRKCZ	S428	R425H	425	Missense	distal	-3	no	55.503	47.074	EPSD;PhosphoSitePlus	COSMIC;CCLE	31.494	Down-regulation
AGC_PKC_PKCi_PRKCZ_ST	Q15831	STK11	Q05513	PRKCZ	S428	R425P	425	Missense	distal	-3	no	55.503	36.632	EPSD;PhosphoSitePlus	COSMIC	31.494	Down-regulation
AGC_PKC_PKCi_PRKCZ_ST	Q15831	STK11	Q05513	PRKCZ	S428	R426W	426	Missense	proximal	-2	no	55.503	37.329	EPSD;PhosphoSitePlus	COSMIC	31.494	Down-regulation
AGC_PKC_PKCi_PRKCZ_ST	O43315	AQP9	Q05513	PRKCZ	S11	A6T	6	Missense	distal	-5	no	36.903	38.245	EPSD;PhosphoSitePlus	COSMIC	31.494	Up-regulation
AGC_PKC_PKCi_PRKCZ_ST	O43315	AQP9	Q05513	PRKCZ	S11	G5A	5	Missense	distal	-6	no	36.903	36.672	EPSD;PhosphoSitePlus	COSMIC	31.494	Down-regulation
AGC_PKC_PKCi_PRKCZ_ST	O43315	AQP9	Q05513	PRKCZ	S11	L18F	18	Missense	distal	7	no	36.903	37.420	EPSD;PhosphoSitePlus	COSMIC	31.494	Up-regulation
AGC_PKC_PKCi_PRKCZ_ST	O43315	AQP9	Q05513	PRKCZ	S20	L18F	18	Missense	proximal	-2	no	32.078	29.331	EPSD	COSMIC	31.494	Loss
AGC_PKC_PKCi_PRKCZ_ST	O43315	AQP9	Q05513	PRKCZ	S20	T26P	26	Missense	distal	6	no	32.078	31.747	EPSD	COSMIC	31.494	Down-regulation
AGC_PKC_PKCi_PRKCZ_ST	O43315	AQP9	Q05513	PRKCZ	S21	L18F	18	Missense	distal	-3	no	44.259	41.554	EPSD	COSMIC	31.494	Down-regulation
AGC_PKC_PKCi_PRKCZ_ST	O43315	AQP9	Q05513	PRKCZ	S21	T26P	26	Missense	distal	5	no	44.259	44.271	EPSD	COSMIC	31.494	Up-regulation
AGC_PKC_PKCi_PRKCZ_ST	O43315	AQP9	Q05513	PRKCZ	S222	L221P	221	Missense	proximal	-1	no	50.080	49.919	PhosphoSitePlus;EPSD	COSMIC	31.494	Down-regulation
AGC_PKC_PKCi_PRKCZ_ST	P35580	MYH10	Q05513	PRKCZ	S201	D207G	207	Missense	distal	6	no	35.045	31.008	EPSD	COSMIC;GDSC;CCLE	31.494	Loss
AGC_PKC_PKCi_PRKCZ_ST	P35580	MYH10	Q05513	PRKCZ	S201	S201P	201	Missense	central	0	yes	35.045	0.000	EPSD	COSMIC	31.494	Loss
AGC_PKC_PKCi_PRKCZ_ST	P35580	MYH10	Q05513	PRKCZ	S201	K206N	206	Missense	distal	5	no	35.045	35.184	EPSD	COSMIC	31.494	Up-regulation
AGC_PKC_PKCi_PRKCZ_ST	P35580	MYH10	Q05513	PRKCZ	S201	H197N	197	Missense	distal	-4	no	35.045	34.987	EPSD	COSMIC	31.494	Down-regulation
AGC_PKC_PKCi_PRKCZ_ST	P35580	MYH10	Q05513	PRKCZ	T233	D237N	237	Missense	distal	4	no	30.796	36.743	EPSD	COSMIC	31.494	Gain
AGC_PKC_PKCi_PRKCZ_ST	P35580	MYH10	Q05513	PRKCZ	S1129	E1122K	1122	Missense	distal	-7	no	31.736	37.557	EPSD	COSMIC	31.494	Up-regulation
AGC_PKC_PKCi_PRKCZ_ST	P35580	MYH10	Q05513	PRKCZ	S1129	E1128K	1128	Missense	proximal	-1	no	31.736	32.850	EPSD	COSMIC	31.494	Up-regulation
AGC_PKC_PKCi_PRKCZ_ST	P35580	MYH10	Q05513	PRKCZ	S1129	R1134W	1134	Missense	distal	5	no	31.736	30.910	EPSD	COSMIC	31.494	Loss
AGC_PKC_PKCi_PRKCZ_ST	P35580	MYH10	Q05513	PRKCZ	S1129	E1130K	1130	Missense	proximal	1	no	31.736	33.678	EPSD	COSMIC	31.494	Up-regulation
AGC_PKC_PKCi_PRKCZ_ST	P35580	MYH10	Q05513	PRKCZ	S1487	L1488V	1488	Missense	proximal	1	no	34.944	36.103	EPSD	COSMIC	31.494	Up-regulation
AGC_PKC_PKCi_PRKCZ_ST	P35580	MYH10	Q05513	PRKCZ	S1684	E1686Q	1686	Missense	proximal	2	no	30.223	34.503	EPSD	COSMIC	31.494	Gain
AGC_PKC_PKCi_PRKCZ_ST	P35580	MYH10	Q05513	PRKCZ	S1684	E1677Q	1677	Missense	distal	-7	no	30.223	32.773	EPSD	COSMIC	31.494	Gain
AGC_PKC_PKCi_PRKCZ_ST	P35580	MYH10	Q05513	PRKCZ	S1699	E1694D	1694	Missense	distal	-5	no	36.838	36.301	EPSD	COSMIC	31.494	Down-regulation
AGC_PKC_PKCi_PRKCZ_ST	P35580	MYH10	Q05513	PRKCZ	S1699	E1694V	1694	Missense	distal	-5	no	36.838	37.520	EPSD	COSMIC	31.494	Up-regulation
AGC_PKC_PKCi_PRKCZ_ST	P35580	MYH10	Q05513	PRKCZ	S1699	A1706T	1706	Missense	distal	7	no	36.838	35.241	EPSD	COSMIC	31.494	Down-regulation
AGC_PKC_PKCi_PRKCZ_ST	P35580	MYH10	Q05513	PRKCZ	S1699	R1701Q	1701	Missense	proximal	2	no	36.838	28.969	EPSD	COSMIC	31.494	Loss
AGC_PKC_PKCi_PRKCZ_ST	P35580	MYH10	Q05513	PRKCZ	S1699	A1706D	1706	Missense	distal	7	no	36.838	38.127	EPSD	COSMIC	31.494	Up-regulation
AGC_PKC_PKCi_PRKCZ_ST	P35580	MYH10	Q05513	PRKCZ	S1922	E1920Q	1920	Missense	proximal	-2	no	33.169	38.302	EPSD	COSMIC	31.494	Up-regulation
AGC_PKC_PKCi_PRKCZ_ST	P35580	MYH10	Q05513	PRKCZ	S1922	R1927W	1927	Missense	distal	5	no	33.169	32.342	EPSD	COSMIC	31.494	Down-regulation
AGC_PKC_PKCi_PRKCZ_ST	P35580	MYH10	Q05513	PRKCZ	S1922	E1915K	1915	Missense	distal	-7	no	33.169	38.989	EPSD	COSMIC	31.494	Up-regulation
AGC_PKC_PKCi_PRKCZ_ST	P35580	MYH10	Q05513	PRKCZ	S1941	R1940Q	1940	Missense	proximal	-1	no	32.737	31.575	EPSD	COSMIC	31.494	Down-regulation
AGC_PKC_PKCi_PRKCZ_ST	P35580	MYH10	Q05513	PRKCZ	S1941	R1944H	1944	Missense	distal	3	no	32.737	26.508	EPSD	COSMIC	31.494	Loss
AGC_PKC_PKCi_PRKCZ_ST	P35580	MYH10	Q05513	PRKCZ	S1941	R1943Q	1943	Missense	proximal	2	no	32.737	24.868	EPSD	COSMIC	31.494	Loss
AGC_PKC_PKCi_PRKCZ_ST	P35580	MYH10	Q05513	PRKCZ	T1960	L1953M	1953	Missense	distal	-7	no	41.311	42.911	EPSD	COSMIC	31.494	Up-regulation
AGC_PKC_PKCi_PRKCZ_ST	P35580	MYH10	Q05513	PRKCZ	T1960	E1961Q	1961	Missense	proximal	1	no	41.311	42.626	EPSD	COSMIC	31.494	Up-regulation
AGC_PKC_PKCi_PRKCZ_ST	P35580	MYH10	Q05513	PRKCZ	S1965	Q1971R	1971	Missense	distal	6	no	50.592	56.484	EPSD	COSMIC	31.494	Up-regulation
AGC_PKC_PKCi_PRKCZ_ST	P35580	MYH10	Q05513	PRKCZ	S1965	E1961Q	1961	Missense	distal	-4	no	50.592	50.347	EPSD	COSMIC	31.494	Down-regulation
AGC_PKC_PKCi_PRKCZ_ST	P35580	MYH10	Q05513	PRKCZ	S1965	P1972S	1972	Missense	distal	7	no	50.592	47.283	EPSD	COSMIC	31.494	Down-regulation
AGC_PKC_PKCi_PRKCZ_ST	Q9UBS0	RPS6KB2	Q05513	PRKCZ	S416	P421S	421	Missense	distal	5	no	48.455	48.433	EPSD	COSMIC	31.494	Down-regulation
AGC_PKC_PKCi_PRKCZ_ST	Q9UBS0	RPS6KB2	Q05513	PRKCZ	S416	R413C	413	Missense	distal	-3	no	48.455	28.421	EPSD	COSMIC	31.494	Loss
AGC_PKC_PKCi_PRKCZ_ST	Q9UBS0	RPS6KB2	Q05513	PRKCZ	S416	R413H	413	Missense	distal	-3	no	48.455	40.026	EPSD	COSMIC	31.494	Down-regulation
AGC_PKC_PKCi_PRKCZ_ST	Q9UBS0	RPS6KB2	Q05513	PRKCZ	S416	P421L	421	Missense	distal	5	no	48.455	48.367	EPSD	COSMIC	31.494	Down-regulation
AGC_PKC_PKCi_PRKCZ_ST	Q9UBS0	RPS6KB2	Q05513	PRKCZ	S417	P421S	421	Missense	distal	4	no	28.746	35.783	EPSD	COSMIC	31.494	Gain
AGC_PKC_PKCi_PRKCZ_ST	Q9UBS0	RPS6KB2	Q05513	PRKCZ	S468	S468P	468	Missense	central	0	yes	51.854	0.000	EPSD	COSMIC	31.494	Loss
AGC_PKC_PKCi_PRKCZ_ST	Q9UBS0	RPS6KB2	Q05513	PRKCZ	S468	P463S	463	Missense	distal	-5	no	51.854	50.462	EPSD	COSMIC	31.494	Down-regulation
AGC_PKC_PKCi_PRKCZ_ST	Q9UBS0	RPS6KB2	Q05513	PRKCZ	S468	R475G	475	Missense	distal	7	no	51.854	54.167	EPSD	COSMIC	31.494	Up-regulation
AGC_PKC_PKCi_PRKCZ_ST	Q9UBS0	RPS6KB2	Q05513	PRKCZ	S468	P467H	467	Missense	proximal	-1	no	51.854	53.013	EPSD	COSMIC	31.494	Up-regulation
AGC_PKC_PKCi_PRKCZ_ST	Q9UBS0	RPS6KB2	Q05513	PRKCZ	S468	R465H	465	Missense	distal	-3	no	51.854	43.425	EPSD	COSMIC	31.494	Down-regulation
AGC_PKC_PKCi_PRKCZ_ST	Q9UBS0	RPS6KB2	Q05513	PRKCZ	T470	P467H	467	Missense	distal	-3	no	29.648	40.090	EPSD	COSMIC	31.494	Gain
AGC_PKC_PKCi_PRKCZ_ST	Q9UBS0	RPS6KB2	Q05513	PRKCZ	S473	R479H	479	Missense	distal	6	no	64.224	63.181	PhosphoSitePlus	COSMIC;CCLE	31.494	Down-regulation
AGC_PKC_PKCi_PRKCZ_ST	Q9UBS0	RPS6KB2	Q05513	PRKCZ	S473	S468P	468	Missense	distal	-5	no	64.224	65.616	PhosphoSitePlus	COSMIC	31.494	Up-regulation
AGC_PKC_PKCi_PRKCZ_ST	Q9UBS0	RPS6KB2	Q05513	PRKCZ	S473	P480Q	480	Missense	distal	7	no	64.224	59.661	PhosphoSitePlus	COSMIC	31.494	Down-regulation
AGC_PKC_PKCi_PRKCZ_ST	Q9UBS0	RPS6KB2	Q05513	PRKCZ	S473	R477H	477	Missense	distal	4	no	64.224	59.847	PhosphoSitePlus	COSMIC	31.494	Down-regulation
AGC_PKC_PKCi_PRKCZ_ST	Q9UBS0	RPS6KB2	Q05513	PRKCZ	S473	R475G	475	Missense	proximal	2	no	64.224	55.065	PhosphoSitePlus	COSMIC	31.494	Down-regulation
AGC_PKC_PKCi_PRKCZ_ST	Q9UBS0	RPS6KB2	Q05513	PRKCZ	S473	P467H	467	Missense	distal	-6	no	64.224	63.818	PhosphoSitePlus	COSMIC	31.494	Down-regulation
AGC_PKC_PKCi_PRKCZ_ST	P08047	SP1	Q05513	PRKCZ	S73	E72K	72	Missense	proximal	-1	no	40.983	42.097	EPSD	COSMIC	31.494	Up-regulation
AGC_PKC_PKCi_PRKCZ_ST	P08047	SP1	Q05513	PRKCZ	S73	N79K	79	Missense	distal	6	no	40.983	41.485	EPSD	COSMIC	31.494	Up-regulation
AGC_PKC_PKCi_PRKCZ_ST	P08047	SP1	Q05513	PRKCZ	T579	G572D	572	Missense	distal	-7	no	36.072	38.207	EPSD	COSMIC	31.494	Up-regulation
AGC_PKC_PKCi_PRKCZ_ST	P08047	SP1	Q05513	PRKCZ	T579	G572C	572	Missense	distal	-7	no	36.072	34.913	EPSD	COSMIC;GDSC;CCLE	31.494	Down-regulation
AGC_PKC_PKCi_PRKCZ_ST	P08047	SP1	Q05513	PRKCZ	T640	R644W	644	Missense	distal	4	no	34.592	20.721	EPSD	COSMIC	31.494	Loss
AGC_PKC_PKCi_PRKCZ_ST	P08047	SP1	Q05513	PRKCZ	T640	S641C	641	Missense	proximal	1	no	34.592	34.715	EPSD	COSMIC	31.494	Up-regulation
AGC_PKC_PKCi_PRKCZ_ST	P08047	SP1	Q05513	PRKCZ	S641	R644W	644	Missense	distal	3	no	39.294	24.498	EPSD;PhosphoSitePlus	COSMIC	31.494	Loss
AGC_PKC_PKCi_PRKCZ_ST	P08047	SP1	Q05513	PRKCZ	S641	S641C	641	Missense	central	0	yes	39.294	0.000	EPSD;PhosphoSitePlus	COSMIC	31.494	Loss
AGC_PKC_PKCi_PRKCZ_ST	P08047	SP1	Q05513	PRKCZ	S641	R648C	648	Missense	distal	7	no	39.294	42.557	EPSD;PhosphoSitePlus	COSMIC	31.494	Up-regulation
AGC_PKC_PKCi_PRKCZ_ST	P08047	SP1	Q05513	PRKCZ	S641	R648H	648	Missense	distal	7	no	39.294	38.753	EPSD;PhosphoSitePlus	COSMIC	31.494	Down-regulation
AGC_PKC_PKCi_PRKCZ_ST	P08047	SP1	Q05513	PRKCZ	T651	R654M	654	Missense	distal	3	no	36.603	29.491	EPSD	COSMIC	31.494	Loss
AGC_PKC_PKCi_PRKCZ_ST	P08047	SP1	Q05513	PRKCZ	T651	R644W	644	Missense	distal	-7	no	36.603	28.451	EPSD	COSMIC	31.494	Loss
AGC_PKC_PKCi_PRKCZ_ST	P08047	SP1	Q05513	PRKCZ	T651	R654G	654	Missense	distal	3	no	36.603	33.080	EPSD	COSMIC	31.494	Down-regulation
AGC_PKC_PKCi_PRKCZ_ST	P08047	SP1	Q05513	PRKCZ	T651	R648C	648	Missense	distal	-3	no	36.603	16.569	EPSD	COSMIC	31.494	Loss
AGC_PKC_PKCi_PRKCZ_ST	P08047	SP1	Q05513	PRKCZ	T651	R648H	648	Missense	distal	-3	no	36.603	28.174	EPSD	COSMIC	31.494	Loss
AGC_PKC_PKCi_PRKCZ_ST	P08047	SP1	Q05513	PRKCZ	T668	Q674H	674	Missense	distal	6	no	40.198	45.047	PhosphoSitePlus;EPSD	COSMIC	31.494	Up-regulation
AGC_PKC_PKCi_PRKCZ_ST	P08047	SP1	Q05513	PRKCZ	T681	Q674H	674	Missense	distal	-7	no	39.768	40.131	EPSD;PhosphoSitePlus	COSMIC	31.494	Up-regulation
AGC_PKC_PKCi_PRKCZ_ST	P08047	SP1	Q05513	PRKCZ	T681	R678H	678	Missense	distal	-3	no	39.768	31.340	EPSD;PhosphoSitePlus	COSMIC	31.494	Loss
AGC_PKC_PKCi_PRKCZ_ST	P08047	SP1	Q05513	PRKCZ	S698	H700Y	700	Missense	proximal	2	no	32.339	26.475	EPSD	COSMIC	31.494	Loss
AGC_PKC_PKCi_PRKCZ_ST	Q6STE5	SMARCD3	Q05513	PRKCZ	S247	P243S	243	Missense	distal	-4	no	36.922	36.523	PhosphoSitePlus	COSMIC	31.494	Down-regulation
AGC_PKC_PKCi_PRKCZ_ST	Q6STE5	SMARCD3	Q05513	PRKCZ	S247	G244V	244	Missense	distal	-3	no	36.922	39.542	PhosphoSitePlus	COSMIC	31.494	Up-regulation
AGC_PKC_PKCi_PRKCZ_ST	Q6STE5	SMARCD3	Q05513	PRKCZ	S428	R425H	425	Missense	distal	-3	no	32.370	23.942	EPSD	COSMIC	31.494	Loss
AGC_PKC_PKCi_PRKCZ_ST	Q6STE5	SMARCD3	Q05513	PRKCZ	S477	R481C	481	Missense	distal	4	no	42.121	25.965	EPSD	COSMIC	31.494	Loss
AGC_PKC_PKCi_PRKCZ_ST	Q6STE5	SMARCD3	Q05513	PRKCZ	S477	N482S	482	Missense	distal	5	no	42.121	41.761	EPSD	COSMIC	31.494	Down-regulation
AGC_PKC_PKCi_PRKCZ_ST	Q6STE5	SMARCD3	Q05513	PRKCZ	S477	R481H	481	Missense	distal	4	no	42.121	37.744	EPSD	COSMIC	31.494	Down-regulation
AGC_PKC_PKCi_PRKCZ_ST	P27448	MARK3	Q05513	PRKCZ	T211	T211R	211	Missense	central	0	yes	41.358	0.000	EPSD	COSMIC	31.494	Loss
AGC_PKC_PKCi_PRKCZ_ST	P27448	MARK3	Q05513	PRKCZ	T211	G207D	207	Missense	distal	-4	no	41.358	41.498	EPSD	COSMIC	31.494	Up-regulation
AGC_PKC_PKCi_PRKCZ_ST	P27448	MARK3	Q05513	PRKCZ	T297	R295S	295	Missense	proximal	-2	no	45.866	33.776	EPSD	COSMIC	31.494	Down-regulation
AGC_PKC_PKCi_PRKCZ_ST	P27448	MARK3	Q05513	PRKCZ	S369	E370Q	370	Missense	proximal	1	no	38.817	40.132	EPSD	COSMIC	31.494	Up-regulation
AGC_PKC_PKCi_PRKCZ_ST	P27448	MARK3	Q05513	PRKCZ	S369	E370A	370	Missense	proximal	1	no	38.817	40.785	EPSD	COSMIC	31.494	Up-regulation
AGC_PKC_PKCi_PRKCZ_ST	P27448	MARK3	Q05513	PRKCZ	S369	E370D	370	Missense	proximal	1	no	38.817	40.289	EPSD	COSMIC;GDSC	31.494	Up-regulation
AGC_PKC_PKCi_PRKCZ_ST	P27448	MARK3	Q05513	PRKCZ	S390	T397S	397	Missense	distal	7	no	32.699	33.899	EPSD	COSMIC	31.494	Up-regulation
AGC_PKC_PKCi_PRKCZ_ST	P27448	MARK3	Q05513	PRKCZ	S390	L393I	393	Missense	distal	3	no	32.699	27.506	EPSD	COSMIC	31.494	Loss
AGC_PKC_PKCi_PRKCZ_ST	P27448	MARK3	Q05513	PRKCZ	S419	K414Q	414	Missense	distal	-5	no	44.793	45.269	EPSD	COSMIC	31.494	Up-regulation
AGC_PKC_PKCi_PRKCZ_ST	P27448	MARK3	Q05513	PRKCZ	S419	R417H	417	Missense	proximal	-2	no	44.793	35.941	EPSD	COSMIC	31.494	Down-regulation
AGC_PKC_PKCi_PRKCZ_ST	P27448	MARK3	Q05513	PRKCZ	S419	Q413E	413	Missense	distal	-6	no	44.793	45.058	EPSD	COSMIC	31.494	Up-regulation
AGC_PKC_PKCi_PRKCZ_ST	P27448	MARK3	Q05513	PRKCZ	T438	K434E	434	Missense	distal	-4	no	39.089	39.418	EPSD	COSMIC	31.494	Up-regulation
AGC_PKC_PKCi_PRKCZ_ST	P27448	MARK3	Q05513	PRKCZ	S456	R453W	453	Missense	distal	-3	no	33.771	10.015	EPSD	COSMIC;GDSC;CCLE	31.494	Loss
AGC_PKC_PKCi_PRKCZ_ST	P27448	MARK3	Q05513	PRKCZ	T491	P493H	493	Missense	proximal	2	no	25.049	33.440	EPSD	COSMIC	31.494	Gain
AGC_PKC_PKCi_PRKCZ_ST	P27448	MARK3	Q05513	PRKCZ	S495	P493H	493	Missense	proximal	-2	no	26.543	31.627	EPSD	COSMIC	31.494	Gain
AGC_PKC_PKCi_PRKCZ_ST	P27448	MARK3	Q05513	PRKCZ	T507	S511N	511	Missense	distal	4	no	37.529	37.744	EPSD	COSMIC	31.494	Up-regulation
AGC_PKC_PKCi_PRKCZ_ST	P27448	MARK3	Q05513	PRKCZ	T515	S511N	511	Missense	distal	-4	no	32.521	32.378	EPSD	COSMIC	31.494	Down-regulation
AGC_PKC_PKCi_PRKCZ_ST	P27448	MARK3	Q05513	PRKCZ	S618	N616Y	616	Missense	proximal	-2	no	32.789	33.959	EPSD	COSMIC	31.494	Up-regulation
AGC_PKC_PKCi_PRKCZ_ST	P27448	MARK3	Q05513	PRKCZ	S618	M617I	617	Missense	proximal	-1	no	32.789	31.987	EPSD	COSMIC	31.494	Down-regulation
AGC_PKC_PKCi_PRKCZ_ST	P27448	MARK3	Q05513	PRKCZ	S618	R615I	615	Missense	distal	-3	no	32.789	13.643	EPSD	COSMIC	31.494	Loss
AGC_PKC_PKCi_PRKCZ_ST	P27448	MARK3	Q05513	PRKCZ	S643	S638I	638	Missense	distal	-5	no	36.166	35.255	EPSD	COSMIC	31.494	Down-regulation
AGC_PKC_PKCi_PRKCZ_ST	P27448	MARK3	Q05513	PRKCZ	S643	R640C	640	Missense	distal	-3	no	36.166	16.132	EPSD	COSMIC	31.494	Loss
AGC_PKC_PKCi_PRKCZ_ST	P27448	MARK3	Q05513	PRKCZ	S643	Q646H	646	Missense	distal	3	no	36.166	35.533	EPSD	COSMIC	31.494	Down-regulation
AGC_PKC_PKCi_PRKCZ_ST	P27448	MARK3	Q05513	PRKCZ	S643	N641K	641	Missense	proximal	-2	no	36.166	43.731	EPSD	COSMIC	31.494	Up-regulation
AGC_PKC_PKCi_PRKCZ_ST	P27448	MARK3	Q05513	PRKCZ	S643	N650K	650	Missense	distal	7	no	36.166	35.698	EPSD	COSMIC	31.494	Down-regulation
AGC_PKC_PKCi_PRKCZ_ST	P27448	MARK3	Q05513	PRKCZ	S643	E636D	636	Missense	distal	-7	no	36.166	39.889	EPSD	COSMIC	31.494	Up-regulation
AGC_PKC_PKCi_PRKCZ_ST	P27448	MARK3	Q05513	PRKCZ	S734	S734L	734	Missense	central	0	yes	44.141	0.000	EPSD	COSMIC;GDSC	31.494	Loss
AGC_PKC_PKCi_PRKCZ_ST	P27448	MARK3	Q05513	PRKCZ	S734	R729W	729	Missense	distal	-5	no	44.141	47.830	EPSD	COSMIC	31.494	Up-regulation
AGC_PKC_PKCi_PRKCZ_ST	P27448	MARK3	Q05513	PRKCZ	S734	A739V	739	Missense	distal	5	no	44.141	43.668	EPSD	COSMIC	31.494	Down-regulation
AGC_PKC_PKCi_PRKCZ_ST	Q96RI1	NR1H4	Q05513	PRKCZ	S164	G159S	159	Missense	distal	-5	no	42.692	42.614	EPSD	COSMIC	31.494	Down-regulation
AGC_PKC_PKCi_PRKCZ_ST	Q96RI1	NR1H4	Q05513	PRKCZ	S164	G159C	159	Missense	distal	-5	no	42.692	44.161	EPSD	COSMIC	31.494	Up-regulation
AGC_PKC_PKCi_PRKCZ_ST	Q96RI1	NR1H4	Q05513	PRKCZ	S164	F160L	160	Missense	distal	-4	no	42.692	42.840	EPSD	COSMIC	31.494	Up-regulation
AGC_PKC_PKCi_PRKCZ_ST	Q96RI1	NR1H4	Q05513	PRKCZ	T456	R455W	455	Missense	proximal	-1	no	37.875	35.349	EPSD	COSMIC;CCLE	31.494	Down-regulation
AGC_PKC_PKCi_PRKCZ_ST	Q96RI1	NR1H4	Q05513	PRKCZ	T456	H461N	461	Missense	distal	5	no	37.875	38.058	EPSD	COSMIC	31.494	Up-regulation
AGC_PKC_PKCi_PRKCZ_ST	Q96RI1	NR1H4	Q05513	PRKCZ	S467	M466K	466	Missense	proximal	-1	no	45.617	45.901	EPSD	COSMIC	31.494	Up-regulation
AGC_PKC_PKCi_PRKCZ_ST	Q96RI1	NR1H4	Q05513	PRKCZ	S467	D472N	472	Missense	distal	5	no	45.617	45.701	EPSD	COSMIC	31.494	Up-regulation
AGC_PKC_PKCi_PRKCZ_ST	Q96RI1	NR1H4	Q05513	PRKCZ	S467	H461N	461	Missense	distal	-6	no	45.617	45.753	EPSD	COSMIC	31.494	Up-regulation
AGC_PKC_PKCi_PRKCZ_ST	Q96A00	PPP1R14A	Q05513	PRKCZ	S16	A20T	20	Missense	distal	4	no	43.768	37.912	EPSD	COSMIC	31.494	Down-regulation
AGC_PKC_PKCi_PRKCZ_ST	Q96A00	PPP1R14A	Q05513	PRKCZ	S16	P23A	23	Missense	distal	7	no	43.768	40.857	EPSD	COSMIC	31.494	Down-regulation
AGC_PKC_PKCi_PRKCZ_ST	Q96A00	PPP1R14A	Q05513	PRKCZ	T38	V39I	39	Missense	proximal	1	no	42.752	42.277	PhosphoSitePlus	COSMIC;CCLE	31.494	Down-regulation
AGC_PKC_PKCi_PRKCZ_ST	Q96A00	PPP1R14A	Q05513	PRKCZ	T38	D42N	42	Missense	distal	4	no	42.752	48.698	PhosphoSitePlus	COSMIC	31.494	Up-regulation
AGC_PKC_PKCi_PRKCZ_ST	Q96A00	PPP1R14A	Q05513	PRKCZ	S130	S136N	136	Missense	distal	6	no	36.539	37.170	EPSD	COSMIC	31.494	Up-regulation
AGC_PKC_PKCi_PRKCZ_ST	Q96A00	PPP1R14A	Q05513	PRKCZ	S136	S136N	136	Missense	central	0	yes	32.355	0.000	EPSD	COSMIC	31.494	Loss
AGC_PKC_PKCi_PRKCZ_ST	Q96A00	PPP1R14A	Q05513	PRKCZ	S136	L138F	138	Missense	proximal	2	no	32.355	28.744	EPSD	COSMIC	31.494	Loss
AGC_PKC_PKCi_PRKCZ_ST	Q96A00	PPP1R14A	Q05513	PRKCZ	S136	R141W	141	Missense	distal	5	no	32.355	31.528	EPSD	COSMIC;GDSC	31.494	Down-regulation
AGC_PKC_PKCi_PRKCZ_ST	P35568	IRS1	Q05513	PRKCZ	S24	K27R	27	Missense	distal	3	no	37.310	38.038	EPSD	COSMIC	31.494	Up-regulation
AGC_PKC_PKCi_PRKCZ_ST	P35568	IRS1	Q05513	PRKCZ	S24	V31I	31	Missense	distal	7	no	37.310	39.961	EPSD	COSMIC	31.494	Up-regulation
AGC_PKC_PKCi_PRKCZ_ST	P35568	IRS1	Q05513	PRKCZ	S24	G17C	17	Missense	distal	-7	no	37.310	36.151	EPSD	COSMIC	31.494	Down-regulation
AGC_PKC_PKCi_PRKCZ_ST	P35568	IRS1	Q05513	PRKCZ	T88	E91K	91	Missense	distal	3	no	22.913	32.356	EPSD	COSMIC	31.494	Gain
AGC_PKC_PKCi_PRKCZ_ST	P35568	IRS1	Q05513	PRKCZ	S268	R265C	265	Missense	distal	-3	no	36.016	15.983	EPSD	COSMIC	31.494	Loss
AGC_PKC_PKCi_PRKCZ_ST	P35568	IRS1	Q05513	PRKCZ	S268	S274P	274	Missense	distal	6	no	36.016	34.304	EPSD	COSMIC	31.494	Down-regulation
AGC_PKC_PKCi_PRKCZ_ST	P35568	IRS1	Q05513	PRKCZ	S303	R301C	301	Missense	proximal	-2	no	39.220	25.429	EPSD	COSMIC	31.494	Loss
AGC_PKC_PKCi_PRKCZ_ST	P35568	IRS1	Q05513	PRKCZ	S303	Q296R	296	Missense	distal	-7	no	39.220	42.933	EPSD	COSMIC;GDSC	31.494	Up-regulation
AGC_PKC_PKCi_PRKCZ_ST	P35568	IRS1	Q05513	PRKCZ	S303	E306K	306	Missense	distal	3	no	39.220	48.663	EPSD	COSMIC	31.494	Up-regulation
AGC_PKC_PKCi_PRKCZ_ST	P35568	IRS1	Q05513	PRKCZ	S303	A310T	310	Missense	distal	7	no	39.220	37.623	EPSD	COSMIC	31.494	Down-regulation
AGC_PKC_PKCi_PRKCZ_ST	P35568	IRS1	Q05513	PRKCZ	S303	R302L	302	Missense	proximal	-1	no	39.220	37.423	EPSD	COSMIC	31.494	Down-regulation
AGC_PKC_PKCi_PRKCZ_ST	P35568	IRS1	Q05513	PRKCZ	S303	I308M	308	Missense	distal	5	no	39.220	39.259	EPSD	COSMIC	31.494	Up-regulation
AGC_PKC_PKCi_PRKCZ_ST	P35568	IRS1	Q05513	PRKCZ	S303	A310V	310	Missense	distal	7	no	39.220	38.967	EPSD	COSMIC	31.494	Down-regulation
AGC_PKC_PKCi_PRKCZ_ST	P35568	IRS1	Q05513	PRKCZ	S307	R301C	301	Missense	distal	-6	no	35.352	35.962	EPSD	COSMIC	31.494	Up-regulation
AGC_PKC_PKCi_PRKCZ_ST	P35568	IRS1	Q05513	PRKCZ	S307	E306K	306	Missense	proximal	-1	no	35.352	36.466	EPSD	COSMIC	31.494	Up-regulation
AGC_PKC_PKCi_PRKCZ_ST	P35568	IRS1	Q05513	PRKCZ	S307	A310T	310	Missense	distal	3	no	35.352	29.143	EPSD	COSMIC	31.494	Loss
AGC_PKC_PKCi_PRKCZ_ST	P35568	IRS1	Q05513	PRKCZ	S307	P313L	313	Missense	distal	6	no	35.352	37.284	EPSD	COSMIC;GDSC;CCLE	31.494	Up-regulation
AGC_PKC_PKCi_PRKCZ_ST	P35568	IRS1	Q05513	PRKCZ	S307	R302L	302	Missense	distal	-5	no	35.352	38.905	EPSD	COSMIC	31.494	Up-regulation
AGC_PKC_PKCi_PRKCZ_ST	P35568	IRS1	Q05513	PRKCZ	S307	I308M	308	Missense	proximal	1	no	35.352	36.229	EPSD	COSMIC	31.494	Up-regulation
AGC_PKC_PKCi_PRKCZ_ST	P35568	IRS1	Q05513	PRKCZ	S307	A310V	310	Missense	distal	3	no	35.352	25.959	EPSD	COSMIC	31.494	Loss
AGC_PKC_PKCi_PRKCZ_ST	P35568	IRS1	Q05513	PRKCZ	S329	E333K	333	Missense	distal	4	no	30.479	32.146	EPSD	COSMIC	31.494	Gain
AGC_PKC_PKCi_PRKCZ_ST	P35568	IRS1	Q05513	PRKCZ	S329	G332R	332	Missense	distal	3	no	30.479	34.002	EPSD	COSMIC	31.494	Gain
AGC_PKC_PKCi_PRKCZ_ST	P35568	IRS1	Q05513	PRKCZ	S362	L369F	369	Missense	distal	7	no	36.695	37.212	EPSD	COSMIC	31.494	Up-regulation
AGC_PKC_PKCi_PRKCZ_ST	P35568	IRS1	Q05513	PRKCZ	S362	A356P	356	Missense	distal	-6	no	36.695	37.218	EPSD	COSMIC	31.494	Up-regulation
AGC_PKC_PKCi_PRKCZ_ST	P35568	IRS1	Q05513	PRKCZ	S362	R364Q	364	Missense	proximal	2	no	36.695	28.826	EPSD	COSMIC	31.494	Loss
AGC_PKC_PKCi_PRKCZ_ST	P35568	IRS1	Q05513	PRKCZ	S362	R358Q	358	Missense	distal	-4	no	36.695	36.881	EPSD	COSMIC	31.494	Up-regulation
AGC_PKC_PKCi_PRKCZ_ST	P35568	IRS1	Q05513	PRKCZ	S362	G361S	361	Missense	proximal	-1	no	36.695	36.048	EPSD	COSMIC	31.494	Down-regulation
AGC_PKC_PKCi_PRKCZ_ST	P35568	IRS1	Q05513	PRKCZ	S413	S415L	415	Missense	proximal	2	no	47.563	50.122	EPSD	COSMIC	31.494	Up-regulation
AGC_PKC_PKCi_PRKCZ_ST	P35568	IRS1	Q05513	PRKCZ	S413	G418V	418	Missense	distal	5	no	47.563	47.225	EPSD	COSMIC;GDSC;CCLE	31.494	Down-regulation
AGC_PKC_PKCi_PRKCZ_ST	P35568	IRS1	Q05513	PRKCZ	S441	P435L	435	Missense	distal	-6	no	36.739	36.488	EPSD;PhosphoSitePlus	COSMIC	31.494	Down-regulation
AGC_PKC_PKCi_PRKCZ_ST	P35568	IRS1	Q05513	PRKCZ	S441	R439Q	439	Missense	proximal	-2	no	36.739	26.753	EPSD;PhosphoSitePlus	COSMIC	31.494	Loss
AGC_PKC_PKCi_PRKCZ_ST	P35568	IRS1	Q05513	PRKCZ	S441	D448E	448	Missense	distal	7	no	36.739	36.000	EPSD;PhosphoSitePlus	COSMIC	31.494	Down-regulation
AGC_PKC_PKCi_PRKCZ_ST	P35568	IRS1	Q05513	PRKCZ	S441	S441Y	441	Missense	central	0	yes	36.739	0.000	EPSD;PhosphoSitePlus	COSMIC	31.494	Loss
AGC_PKC_PKCi_PRKCZ_ST	P35568	IRS1	Q05513	PRKCZ	S441	S434G	434	Missense	distal	-7	no	36.739	37.216	EPSD;PhosphoSitePlus	COSMIC	31.494	Up-regulation
AGC_PKC_PKCi_PRKCZ_ST	P35568	IRS1	Q05513	PRKCZ	S441	S441F	441	Missense	central	0	yes	36.739	0.000	EPSD;PhosphoSitePlus	COSMIC	31.494	Loss
AGC_PKC_PKCi_PRKCZ_ST	P35568	IRS1	Q05513	PRKCZ	S441	R443C	443	Missense	proximal	2	no	36.739	25.550	EPSD;PhosphoSitePlus	COSMIC	31.494	Loss
AGC_PKC_PKCi_PRKCZ_ST	P35568	IRS1	Q05513	PRKCZ	S441	P435F	435	Missense	distal	-6	no	36.739	36.566	EPSD;PhosphoSitePlus	COSMIC	31.494	Down-regulation
AGC_PKC_PKCi_PRKCZ_ST	P35568	IRS1	Q05513	PRKCZ	S441	P447L	447	Missense	distal	6	no	36.739	38.671	EPSD;PhosphoSitePlus	COSMIC	31.494	Up-regulation
AGC_PKC_PKCi_PRKCZ_ST	P35568	IRS1	Q05513	PRKCZ	S441	R443L	443	Missense	proximal	2	no	36.739	29.272	EPSD;PhosphoSitePlus	COSMIC	31.494	Loss
AGC_PKC_PKCi_PRKCZ_ST	P35568	IRS1	Q05513	PRKCZ	S441	S444I	444	Missense	distal	3	no	36.739	32.823	EPSD;PhosphoSitePlus	COSMIC	31.494	Down-regulation
AGC_PKC_PKCi_PRKCZ_ST	P35568	IRS1	Q05513	PRKCZ	T446	T453I	453	Missense	distal	7	no	28.495	32.490	EPSD	COSMIC	31.494	Gain
AGC_PKC_PKCi_PRKCZ_ST	P35568	IRS1	Q05513	PRKCZ	S503	G497E	497	Missense	distal	-6	no	33.842	34.049	EPSD	COSMIC	31.494	Up-regulation
AGC_PKC_PKCi_PRKCZ_ST	P35568	IRS1	Q05513	PRKCZ	T525	T530A	530	Missense	distal	5	no	32.377	32.650	EPSD	COSMIC	31.494	Up-regulation
AGC_PKC_PKCi_PRKCZ_ST	P35568	IRS1	Q05513	PRKCZ	T525	R520L	520	Missense	distal	-5	no	32.377	35.930	EPSD	COSMIC	31.494	Up-regulation
AGC_PKC_PKCi_PRKCZ_ST	P35568	IRS1	Q05513	PRKCZ	T525	F521I	521	Missense	distal	-4	no	32.377	32.345	EPSD	COSMIC	31.494	Down-regulation
AGC_PKC_PKCi_PRKCZ_ST	P35568	IRS1	Q05513	PRKCZ	T525	H526Y	526	Missense	proximal	1	no	32.377	31.024	EPSD	COSMIC	31.494	Loss
AGC_PKC_PKCi_PRKCZ_ST	P35568	IRS1	Q05513	PRKCZ	T525	G529D	529	Missense	distal	4	no	32.377	30.848	EPSD	COSMIC	31.494	Loss
AGC_PKC_PKCi_PRKCZ_ST	P35568	IRS1	Q05513	PRKCZ	S527	T530A	530	Missense	distal	3	no	28.667	34.876	EPSD	COSMIC	31.494	Gain
AGC_PKC_PKCi_PRKCZ_ST	P35568	IRS1	Q05513	PRKCZ	S527	G529D	529	Missense	proximal	2	no	28.667	33.876	EPSD	COSMIC	31.494	Gain
AGC_PKC_PKCi_PRKCZ_ST	P35568	IRS1	Q05513	PRKCZ	S574	P578S	578	Missense	distal	4	no	33.848	40.885	EPSD	COSMIC	31.494	Up-regulation
AGC_PKC_PKCi_PRKCZ_ST	P35568	IRS1	Q05513	PRKCZ	S574	F576L	576	Missense	proximal	2	no	33.848	37.459	EPSD	COSMIC	31.494	Up-regulation
AGC_PKC_PKCi_PRKCZ_ST	P35568	IRS1	Q05513	PRKCZ	T851	L855P	855	Missense	distal	4	no	31.817	35.603	EPSD	COSMIC	31.494	Up-regulation
AGC_PKC_PKCi_PRKCZ_ST	P35568	IRS1	Q05513	PRKCZ	T851	A849S	849	Missense	proximal	-2	no	31.817	29.787	EPSD	COSMIC	31.494	Loss
AGC_PKC_PKCi_PRKCZ_ST	P35568	IRS1	Q05513	PRKCZ	T851	R857Q	857	Missense	distal	6	no	31.817	25.925	EPSD	COSMIC	31.494	Loss
AGC_PKC_PKCi_PRKCZ_ST	P35568	IRS1	Q05513	PRKCZ	T851	R854L	854	Missense	distal	3	no	31.817	23.597	EPSD	COSMIC	31.494	Loss
AGC_PKC_PKCi_PRKCZ_ST	P35568	IRS1	Q05513	PRKCZ	T851	P858H	858	Missense	distal	7	no	31.817	28.011	EPSD	COSMIC	31.494	Loss
AGC_PKC_PKCi_PRKCZ_ST	P35568	IRS1	Q05513	PRKCZ	T851	T847A	847	Missense	distal	-4	no	31.817	31.769	EPSD	COSMIC	31.494	Down-regulation
AGC_PKC_PKCi_PRKCZ_ST	P35568	IRS1	Q05513	PRKCZ	S984	P983S	983	Missense	proximal	-1	no	32.534	33.390	EPSD	COSMIC	31.494	Up-regulation
AGC_PKC_PKCi_PRKCZ_ST	P35568	IRS1	Q05513	PRKCZ	S984	S985N	985	Missense	proximal	1	no	32.534	33.057	EPSD	COSMIC	31.494	Up-regulation
AGC_PKC_PKCi_PRKCZ_ST	P35568	IRS1	Q05513	PRKCZ	S995	M992K	992	Missense	distal	-3	no	28.875	34.725	EPSD	COSMIC	31.494	Gain
AGC_PKC_PKCi_PRKCZ_ST	P35568	IRS1	Q05513	PRKCZ	S1005	P1009S	1009	Missense	distal	4	no	27.052	34.089	EPSD	COSMIC	31.494	Gain
AGC_PKC_PKCi_PRKCZ_ST	P35568	IRS1	Q05513	PRKCZ	S1037	A1042T	1042	Missense	distal	5	no	31.965	31.692	EPSD	COSMIC	31.494	Down-regulation
AGC_PKC_PKCi_PRKCZ_ST	P35568	IRS1	Q05513	PRKCZ	S1037	S1043F	1043	Missense	distal	6	no	31.965	27.762	EPSD	COSMIC	31.494	Loss
AGC_PKC_PKCi_PRKCZ_ST	P35568	IRS1	Q05513	PRKCZ	S1100	R1097W	1097	Missense	distal	-3	no	34.706	10.950	EPSD	COSMIC	31.494	Loss
AGC_PKC_PKCi_PRKCZ_ST	P35568	IRS1	Q05513	PRKCZ	S1100	E1102K	1102	Missense	proximal	2	no	34.706	44.312	EPSD	COSMIC	31.494	Up-regulation
AGC_PKC_PKCi_PRKCZ_ST	P35568	IRS1	Q05513	PRKCZ	S1101	R1097W	1097	Missense	distal	-4	no	30.885	31.605	EPSD	COSMIC	31.494	Gain
AGC_PKC_PKCi_PRKCZ_ST	P35568	IRS1	Q05513	PRKCZ	S1101	E1102K	1102	Missense	proximal	1	no	30.885	32.826	EPSD	COSMIC	31.494	Gain
AGC_PKC_PKCi_PRKCZ_ST	P35568	IRS1	Q05513	PRKCZ	S1142	R1140C	1140	Missense	proximal	-2	no	38.241	24.450	EPSD	COSMIC;CCLE	31.494	Loss
AGC_PKC_PKCi_PRKCZ_ST	P35568	IRS1	Q05513	PRKCZ	S1143	R1140C	1140	Missense	distal	-3	no	38.195	18.161	EPSD	COSMIC;CCLE	31.494	Loss
AGC_PKC_PKCi_PRKCZ_ST	P35568	IRS1	Q05513	PRKCZ	S1218	G1212V	1212	Missense	distal	-6	no	40.982	41.115	EPSD	COSMIC	31.494	Up-regulation
AGC_PKC_PKCi_PRKCZ_ST	P35568	IRS1	Q05513	PRKCZ	S1218	R1220C	1220	Missense	proximal	2	no	40.982	29.793	EPSD	COSMIC	31.494	Loss
AGC_PKC_PKCi_PRKCZ_ST	P35568	IRS1	Q05513	PRKCZ	S1218	D1225Y	1225	Missense	distal	7	no	40.982	41.658	EPSD	COSMIC	31.494	Up-regulation
AGC_PKC_PKCi_PRKCZ_ST	P35568	IRS1	Q05513	PRKCZ	S1218	E1224Q	1224	Missense	distal	6	no	40.982	39.862	EPSD	COSMIC	31.494	Down-regulation
AGC_PKC_PKCi_PRKCZ_ST	P35568	IRS1	Q05513	PRKCZ	T1219	G1212V	1212	Missense	distal	-7	no	41.313	39.819	EPSD	COSMIC	31.494	Down-regulation
AGC_PKC_PKCi_PRKCZ_ST	P35568	IRS1	Q05513	PRKCZ	T1219	R1220C	1220	Missense	proximal	1	no	41.313	38.997	EPSD	COSMIC	31.494	Down-regulation
AGC_PKC_PKCi_PRKCZ_ST	P35568	IRS1	Q05513	PRKCZ	T1219	D1225Y	1225	Missense	distal	6	no	41.313	34.120	EPSD	COSMIC	31.494	Down-regulation
AGC_PKC_PKCi_PRKCZ_ST	P35568	IRS1	Q05513	PRKCZ	T1219	E1224Q	1224	Missense	distal	5	no	41.313	41.312	EPSD	COSMIC	31.494	Down-regulation
AGC_PKC_PKCi_PRKCZ_ST	P35568	IRS1	Q05513	PRKCZ	T1219	L1226V	1226	Missense	distal	7	no	41.313	40.678	EPSD	COSMIC	31.494	Down-regulation
AGC_PKC_PKCi_PRKCZ_ST	P35568	IRS1	Q05513	PRKCZ	S1222	R1220C	1220	Missense	proximal	-2	no	41.403	27.612	EPSD	COSMIC	31.494	Loss
AGC_PKC_PKCi_PRKCZ_ST	P35568	IRS1	Q05513	PRKCZ	S1222	D1225Y	1225	Missense	distal	3	no	41.403	34.512	EPSD	COSMIC	31.494	Down-regulation
AGC_PKC_PKCi_PRKCZ_ST	P35568	IRS1	Q05513	PRKCZ	S1222	A1228V	1228	Missense	distal	6	no	41.403	39.482	EPSD	COSMIC	31.494	Down-regulation
AGC_PKC_PKCi_PRKCZ_ST	P35568	IRS1	Q05513	PRKCZ	S1222	E1224Q	1224	Missense	proximal	2	no	41.403	45.682	EPSD	COSMIC	31.494	Up-regulation
AGC_PKC_PKCi_PRKCZ_ST	P35568	IRS1	Q05513	PRKCZ	S1222	L1226V	1226	Missense	distal	4	no	41.403	42.648	EPSD	COSMIC	31.494	Up-regulation
AGC_PKC_PKCi_PRKCZ_ST	P35568	IRS1	Q05513	PRKCZ	S1223	R1220C	1220	Missense	distal	-3	no	49.574	29.540	EPSD	COSMIC	31.494	Loss
AGC_PKC_PKCi_PRKCZ_ST	P35568	IRS1	Q05513	PRKCZ	S1223	D1225Y	1225	Missense	proximal	2	no	49.574	43.506	EPSD	COSMIC	31.494	Down-regulation
AGC_PKC_PKCi_PRKCZ_ST	P35568	IRS1	Q05513	PRKCZ	S1223	A1228V	1228	Missense	distal	5	no	49.574	49.101	EPSD	COSMIC	31.494	Down-regulation
AGC_PKC_PKCi_PRKCZ_ST	P35568	IRS1	Q05513	PRKCZ	S1223	E1224Q	1224	Missense	proximal	1	no	49.574	50.889	EPSD	COSMIC	31.494	Up-regulation
AGC_PKC_PKCi_PRKCZ_ST	P35568	IRS1	Q05513	PRKCZ	S1223	L1226V	1226	Missense	distal	3	no	49.574	45.407	EPSD	COSMIC	31.494	Down-regulation
AGC_PKC_PKCi_PRKCZ_ST	P35568	IRS1	Q05513	PRKCZ	S1227	R1220C	1220	Missense	distal	-7	no	44.292	38.458	EPSD	COSMIC	31.494	Down-regulation
AGC_PKC_PKCi_PRKCZ_ST	P35568	IRS1	Q05513	PRKCZ	S1227	D1225Y	1225	Missense	proximal	-2	no	44.292	39.384	EPSD	COSMIC	31.494	Down-regulation
AGC_PKC_PKCi_PRKCZ_ST	P35568	IRS1	Q05513	PRKCZ	S1227	A1228V	1228	Missense	proximal	1	no	44.292	44.939	EPSD	COSMIC	31.494	Up-regulation
AGC_PKC_PKCi_PRKCZ_ST	P35568	IRS1	Q05513	PRKCZ	S1227	E1224Q	1224	Missense	distal	-3	no	44.292	50.837	EPSD	COSMIC	31.494	Up-regulation
AGC_PKC_PKCi_PRKCZ_ST	P35568	IRS1	Q05513	PRKCZ	S1227	L1226V	1226	Missense	proximal	-1	no	44.292	44.755	EPSD	COSMIC	31.494	Up-regulation
AGC_PKC_PKCi_PRKCZ_ST	Q8N2W9	PIAS4	Q05513	PRKCZ	S18	G25C	25	Missense	distal	7	no	41.522	42.472	PhosphoSitePlus	COSMIC	31.494	Up-regulation
AGC_PKC_PKCi_PRKCZ_ST	Q8N2W9	PIAS4	Q05513	PRKCZ	S18	R16L	16	Missense	proximal	-2	no	41.522	29.963	PhosphoSitePlus	COSMIC	31.494	Loss
AGC_PKC_PKCi_PRKCZ_ST	Q8N2W9	PIAS4	Q05513	PRKCZ	S416	A409T	409	Missense	distal	-7	no	37.456	35.327	EPSD	COSMIC;GDSC	31.494	Down-regulation
AGC_PKC_PKCi_PRKCZ_ST	P35222	CTNNB1	Q05513	PRKCZ	S29	Q26R	26	Missense	distal	-3	no	26.270	38.157	EPSD	COSMIC;GDSC;CCLE	31.494	Gain
AGC_PKC_PKCi_PRKCZ_ST	P35222	CTNNB1	Q05513	PRKCZ	T40	P44S	44	Missense	distal	4	no	24.491	31.528	EPSD	COSMIC	31.494	Gain
AGC_PKC_PKCi_PRKCZ_ST	P35222	CTNNB1	Q05513	PRKCZ	T40	P44A	44	Missense	distal	4	no	24.491	32.124	EPSD	COSMIC	31.494	Gain
AGC_PKC_PKCi_PRKCZ_ST	P35222	CTNNB1	Q05513	PRKCZ	T40	T42R	42	Missense	proximal	2	no	24.491	33.429	EPSD	COSMIC	31.494	Gain
AGC_PKC_PKCi_PRKCZ_ST	P35222	CTNNB1	Q05513	PRKCZ	S45	P44S	44	Missense	proximal	-1	no	30.732	31.588	PhosphoSitePlus	COSMIC	31.494	Gain
AGC_PKC_PKCi_PRKCZ_ST	P35222	CTNNB1	Q05513	PRKCZ	S45	G38A	38	Missense	distal	-7	no	30.732	33.181	PhosphoSitePlus	COSMIC	31.494	Gain
AGC_PKC_PKCi_PRKCZ_ST	P35222	CTNNB1	Q05513	PRKCZ	S45	P44A	44	Missense	proximal	-1	no	30.732	32.280	PhosphoSitePlus	COSMIC	31.494	Gain
AGC_PKC_PKCi_PRKCZ_ST	P35222	CTNNB1	Q05513	PRKCZ	S45	K49R	49	Missense	distal	4	no	30.732	33.463	PhosphoSitePlus	COSMIC	31.494	Gain
AGC_PKC_PKCi_PRKCZ_ST	P35222	CTNNB1	Q05513	PRKCZ	S45	T42R	42	Missense	distal	-3	no	30.732	42.303	PhosphoSitePlus	COSMIC	31.494	Gain
AGC_PKC_PKCi_PRKCZ_ST	P35222	CTNNB1	Q05513	PRKCZ	S45	T42K	42	Missense	distal	-3	no	30.732	37.165	PhosphoSitePlus	COSMIC	31.494	Gain
AGC_PKC_PKCi_PRKCZ_ST	P35222	CTNNB1	Q05513	PRKCZ	S45	S47G	47	Missense	proximal	2	no	30.732	31.599	PhosphoSitePlus	COSMIC	31.494	Gain
AGC_PKC_PKCi_PRKCZ_ST	P35222	CTNNB1	Q05513	PRKCZ	S45	G38D	38	Missense	distal	-7	no	30.732	32.866	PhosphoSitePlus	COSMIC	31.494	Gain
AGC_PKC_PKCi_PRKCZ_ST	P35222	CTNNB1	Q05513	PRKCZ	S45	L46V	46	Missense	proximal	1	no	30.732	31.890	PhosphoSitePlus	COSMIC	31.494	Gain
AGC_PKC_PKCi_PRKCZ_ST	P35222	CTNNB1	Q05513	PRKCZ	S45	S47L	47	Missense	proximal	2	no	30.732	33.291	PhosphoSitePlus	COSMIC	31.494	Gain
AGC_PKC_PKCi_PRKCZ_ST	P35222	CTNNB1	Q05513	PRKCZ	S45	L46M	46	Missense	proximal	1	no	30.732	32.293	PhosphoSitePlus	COSMIC	31.494	Gain
AGC_PKC_PKCi_PRKCZ_ST	P35222	CTNNB1	Q05513	PRKCZ	S45	S47T	47	Missense	proximal	2	no	30.732	31.821	PhosphoSitePlus	COSMIC	31.494	Gain
AGC_PKC_PKCi_PRKCZ_ST	P35222	CTNNB1	Q05513	PRKCZ	S45	S47R	47	Missense	proximal	2	no	30.732	40.758	PhosphoSitePlus	COSMIC	31.494	Gain
AGC_PKC_PKCi_PRKCZ_ST	P35222	CTNNB1	Q05513	PRKCZ	S45	T40P	40	Missense	distal	-5	no	30.732	32.116	PhosphoSitePlus	COSMIC	31.494	Gain
AGC_PKC_PKCi_PRKCZ_ST	P35222	CTNNB1	Q05513	PRKCZ	S222	R225C	225	Missense	distal	3	no	40.754	25.694	EPSD	COSMIC;CCLE	31.494	Loss
AGC_PKC_PKCi_PRKCZ_ST	P35222	CTNNB1	Q05513	PRKCZ	T393	S389L	389	Missense	distal	-4	no	31.311	31.572	EPSD	COSMIC	31.494	Gain
AGC_PKC_PKCi_PRKCZ_ST	P35222	CTNNB1	Q05513	PRKCZ	T472	E479K	479	Missense	distal	7	no	35.794	35.516	EPSD	COSMIC	31.494	Down-regulation
AGC_PKC_PKCi_PRKCZ_ST	P35222	CTNNB1	Q05513	PRKCZ	T472	L468V	468	Missense	distal	-4	no	35.794	35.718	EPSD	COSMIC	31.494	Down-regulation
AGC_PKC_PKCi_PRKCZ_ST	P35222	CTNNB1	Q05513	PRKCZ	T472	A478T	478	Missense	distal	6	no	35.794	32.850	EPSD	COSMIC	31.494	Down-regulation
AGC_PKC_PKCi_PRKCZ_ST	P35222	CTNNB1	Q05513	PRKCZ	T472	H475Q	475	Missense	distal	3	no	35.794	36.426	EPSD	COSMIC	31.494	Up-regulation
AGC_PKC_PKCi_PRKCZ_ST	P35222	CTNNB1	Q05513	PRKCZ	T472	L471Q	471	Missense	proximal	-1	no	35.794	36.429	EPSD	COSMIC	31.494	Up-regulation
AGC_PKC_PKCi_PRKCZ_ST	P35222	CTNNB1	Q05513	PRKCZ	T472	R469C	469	Missense	distal	-3	no	35.794	15.760	EPSD	COSMIC	31.494	Loss
AGC_PKC_PKCi_PRKCZ_ST	P35222	CTNNB1	Q05513	PRKCZ	T472	A478G	478	Missense	distal	6	no	35.794	33.148	EPSD	COSMIC	31.494	Down-regulation
AGC_PKC_PKCi_PRKCZ_ST	P35222	CTNNB1	Q05513	PRKCZ	S473	E479K	479	Missense	distal	6	no	34.823	36.315	EPSD	COSMIC	31.494	Up-regulation
AGC_PKC_PKCi_PRKCZ_ST	P35222	CTNNB1	Q05513	PRKCZ	S473	T472S	472	Missense	proximal	-1	no	34.823	35.078	EPSD	COSMIC	31.494	Up-regulation
AGC_PKC_PKCi_PRKCZ_ST	P35222	CTNNB1	Q05513	PRKCZ	S473	L468V	468	Missense	distal	-5	no	34.823	34.561	EPSD	COSMIC	31.494	Down-regulation
AGC_PKC_PKCi_PRKCZ_ST	P35222	CTNNB1	Q05513	PRKCZ	S473	A478T	478	Missense	distal	5	no	34.823	34.550	EPSD	COSMIC	31.494	Down-regulation
AGC_PKC_PKCi_PRKCZ_ST	P35222	CTNNB1	Q05513	PRKCZ	S473	H475Q	475	Missense	proximal	2	no	34.823	31.107	EPSD	COSMIC	31.494	Loss
AGC_PKC_PKCi_PRKCZ_ST	P35222	CTNNB1	Q05513	PRKCZ	S473	L471Q	471	Missense	proximal	-2	no	34.823	36.396	EPSD	COSMIC	31.494	Up-regulation
AGC_PKC_PKCi_PRKCZ_ST	P35222	CTNNB1	Q05513	PRKCZ	S473	R469C	469	Missense	distal	-4	no	34.823	35.485	EPSD	COSMIC	31.494	Up-regulation
AGC_PKC_PKCi_PRKCZ_ST	P35222	CTNNB1	Q05513	PRKCZ	S473	A478G	478	Missense	distal	5	no	34.823	34.688	EPSD	COSMIC	31.494	Down-regulation
AGC_PKC_PKCi_PRKCZ_ST	P35222	CTNNB1	Q05513	PRKCZ	T547	T551K	551	Missense	distal	4	no	41.763	45.519	EPSD	COSMIC	31.494	Up-regulation
AGC_PKC_PKCi_PRKCZ_ST	P35222	CTNNB1	Q05513	PRKCZ	T547	R549C	549	Missense	proximal	2	no	41.763	30.574	EPSD	COSMIC	31.494	Loss
AGC_PKC_PKCi_PRKCZ_ST	P35222	CTNNB1	Q05513	PRKCZ	T547	Q545K	545	Missense	proximal	-2	no	41.763	46.524	EPSD	COSMIC	31.494	Up-regulation
AGC_PKC_PKCi_PRKCZ_ST	P35222	CTNNB1	Q05513	PRKCZ	T547	A543T	543	Missense	distal	-4	no	41.763	41.811	EPSD	COSMIC	31.494	Up-regulation
AGC_PKC_PKCi_PRKCZ_ST	P35222	CTNNB1	Q05513	PRKCZ	T547	R550H	550	Missense	distal	3	no	41.763	35.534	EPSD	COSMIC	31.494	Down-regulation
AGC_PKC_PKCi_PRKCZ_ST	P35222	CTNNB1	Q05513	PRKCZ	T547	L540F	540	Missense	distal	-7	no	41.763	40.226	EPSD	COSMIC	31.494	Down-regulation
AGC_PKC_PKCi_PRKCZ_ST	P35222	CTNNB1	Q05513	PRKCZ	T547	R550L	550	Missense	distal	3	no	41.763	33.543	EPSD	COSMIC	31.494	Down-regulation
AGC_PKC_PKCi_PRKCZ_ST	P35222	CTNNB1	Q05513	PRKCZ	T547	A543V	543	Missense	distal	-4	no	41.763	42.184	EPSD	COSMIC	31.494	Up-regulation
AGC_PKC_PKCi_PRKCZ_ST	P35222	CTNNB1	Q05513	PRKCZ	T547	D546E	546	Missense	proximal	-1	no	41.763	41.123	EPSD	COSMIC	31.494	Down-regulation
AGC_PKC_PKCi_PRKCZ_ST	P35222	CTNNB1	Q05513	PRKCZ	T547	S552F	552	Missense	distal	5	no	41.763	41.584	EPSD	COSMIC	31.494	Down-regulation
AGC_PKC_PKCi_PRKCZ_ST	P35222	CTNNB1	Q05513	PRKCZ	T547	G554D	554	Missense	distal	7	no	41.763	41.093	EPSD	COSMIC	31.494	Down-regulation
AGC_PKC_PKCi_PRKCZ_ST	P35222	CTNNB1	Q05513	PRKCZ	T547	R550Q	550	Missense	distal	3	no	41.763	36.166	EPSD	COSMIC	31.494	Down-regulation
AGC_PKC_PKCi_PRKCZ_ST	P35222	CTNNB1	Q05513	PRKCZ	T547	T551I	551	Missense	distal	4	no	41.763	39.904	EPSD	COSMIC	31.494	Down-regulation
AGC_PKC_PKCi_PRKCZ_ST	P35222	CTNNB1	Q05513	PRKCZ	S552	T551K	551	Missense	proximal	-1	no	34.285	35.143	EPSD	COSMIC	31.494	Up-regulation
AGC_PKC_PKCi_PRKCZ_ST	P35222	CTNNB1	Q05513	PRKCZ	S552	R549C	549	Missense	distal	-3	no	34.285	14.251	EPSD	COSMIC	31.494	Loss
AGC_PKC_PKCi_PRKCZ_ST	P35222	CTNNB1	Q05513	PRKCZ	S552	Q545K	545	Missense	distal	-7	no	34.285	37.555	EPSD	COSMIC	31.494	Up-regulation
AGC_PKC_PKCi_PRKCZ_ST	P35222	CTNNB1	Q05513	PRKCZ	S552	Q558H	558	Missense	distal	6	no	34.285	39.134	EPSD	COSMIC	31.494	Up-regulation
AGC_PKC_PKCi_PRKCZ_ST	P35222	CTNNB1	Q05513	PRKCZ	S552	G555A	555	Missense	distal	3	no	34.285	34.814	EPSD	COSMIC	31.494	Up-regulation
AGC_PKC_PKCi_PRKCZ_ST	P35222	CTNNB1	Q05513	PRKCZ	S552	R550H	550	Missense	proximal	-2	no	34.285	25.432	EPSD	COSMIC	31.494	Loss
AGC_PKC_PKCi_PRKCZ_ST	P35222	CTNNB1	Q05513	PRKCZ	S552	R550L	550	Missense	proximal	-2	no	34.285	22.725	EPSD	COSMIC	31.494	Loss
AGC_PKC_PKCi_PRKCZ_ST	P35222	CTNNB1	Q05513	PRKCZ	S552	D546E	546	Missense	distal	-6	no	34.285	34.493	EPSD	COSMIC	31.494	Up-regulation
AGC_PKC_PKCi_PRKCZ_ST	P35222	CTNNB1	Q05513	PRKCZ	S552	S552F	552	Missense	central	0	yes	34.285	0.000	EPSD	COSMIC	31.494	Loss
AGC_PKC_PKCi_PRKCZ_ST	P35222	CTNNB1	Q05513	PRKCZ	S552	T547S	547	Missense	distal	-5	no	34.285	34.278	EPSD	COSMIC	31.494	Down-regulation
AGC_PKC_PKCi_PRKCZ_ST	P35222	CTNNB1	Q05513	PRKCZ	S552	G554D	554	Missense	proximal	2	no	34.285	39.494	EPSD	COSMIC	31.494	Up-regulation
AGC_PKC_PKCi_PRKCZ_ST	P35222	CTNNB1	Q05513	PRKCZ	S552	R550Q	550	Missense	proximal	-2	no	34.285	24.298	EPSD	COSMIC	31.494	Loss
AGC_PKC_PKCi_PRKCZ_ST	P35222	CTNNB1	Q05513	PRKCZ	S552	T551I	551	Missense	proximal	-1	no	34.285	34.058	EPSD	COSMIC	31.494	Down-regulation
AGC_PKC_PKCi_PRKCZ_ST	P35222	CTNNB1	Q05513	PRKCZ	S675	E677D	677	Missense	proximal	2	no	26.994	35.193	EPSD	COSMIC	31.494	Gain
AGC_PKC_PKCi_PRKCZ_ST	P35222	CTNNB1	Q05513	PRKCZ	S680	E677D	677	Missense	distal	-3	no	27.933	37.892	EPSD	COSMIC	31.494	Gain
AGC_PKC_PKCi_PRKCZ_ST	P35612	ADD2	Q05513	PRKCZ	S25	P29L	29	Missense	distal	4	no	38.606	34.820	EPSD	COSMIC	31.494	Down-regulation
AGC_PKC_PKCi_PRKCZ_ST	P35612	ADD2	Q05513	PRKCZ	S25	Q18R	18	Missense	distal	-7	no	38.606	42.319	EPSD	COSMIC	31.494	Up-regulation
AGC_PKC_PKCi_PRKCZ_ST	P35612	ADD2	Q05513	PRKCZ	S25	R23C	23	Missense	proximal	-2	no	38.606	24.815	EPSD	COSMIC	31.494	Loss
AGC_PKC_PKCi_PRKCZ_ST	P35612	ADD2	Q05513	PRKCZ	S25	E30K	30	Missense	distal	5	no	38.606	38.868	EPSD	COSMIC	31.494	Up-regulation
AGC_PKC_PKCi_PRKCZ_ST	P35612	ADD2	Q05513	PRKCZ	S472	S471N	471	Missense	proximal	-1	no	40.395	40.137	EPSD	COSMIC	31.494	Down-regulation
AGC_PKC_PKCi_PRKCZ_ST	P35612	ADD2	Q05513	PRKCZ	T631	E624D	624	Missense	distal	-7	no	37.410	41.134	EPSD	COSMIC	31.494	Up-regulation
AGC_PKC_PKCi_PRKCZ_ST	P35612	ADD2	Q05513	PRKCZ	S703	P702S	702	Missense	proximal	-1	no	32.105	32.961	EPSD	COSMIC	31.494	Up-regulation
AGC_PKC_PKCi_PRKCZ_ST	P35612	ADD2	Q05513	PRKCZ	S703	P698L	698	Missense	distal	-5	no	32.105	32.228	EPSD	COSMIC	31.494	Up-regulation
AGC_PKC_PKCi_PRKCZ_ST	P35612	ADD2	Q05513	PRKCZ	S703	F709Y	709	Missense	distal	6	no	32.105	32.069	EPSD	COSMIC	31.494	Down-regulation
AGC_PKC_PKCi_PRKCZ_ST	P35612	ADD2	Q05513	PRKCZ	S703	F709L	709	Missense	distal	6	no	32.105	36.526	EPSD	COSMIC	31.494	Up-regulation
AGC_PKC_PKCi_PRKCZ_ST	P35612	ADD2	Q05513	PRKCZ	S713	P712S	712	Missense	proximal	-1	no	51.158	52.014	PhosphoSitePlus	COSMIC	31.494	Up-regulation
AGC_PKC_PKCi_PRKCZ_ST	P35612	ADD2	Q05513	PRKCZ	S713	F709Y	709	Missense	distal	-4	no	51.158	51.075	PhosphoSitePlus	COSMIC	31.494	Down-regulation
AGC_PKC_PKCi_PRKCZ_ST	P35612	ADD2	Q05513	PRKCZ	S713	S718R	718	Missense	distal	5	no	51.158	51.744	PhosphoSitePlus	COSMIC;GDSC;CCLE	31.494	Up-regulation
AGC_PKC_PKCi_PRKCZ_ST	P35612	ADD2	Q05513	PRKCZ	S713	F709L	709	Missense	distal	-4	no	51.158	51.307	PhosphoSitePlus	COSMIC	31.494	Up-regulation
AGC_PKC_PKCi_PRKCZ_ST	P35612	ADD2	Q05513	PRKCZ	S718	P712S	712	Missense	distal	-6	no	50.333	50.056	EPSD	COSMIC	31.494	Down-regulation
AGC_PKC_PKCi_PRKCZ_ST	P35612	ADD2	Q05513	PRKCZ	S718	S718R	718	Missense	central	0	yes	50.333	0.000	EPSD	COSMIC;GDSC;CCLE	31.494	Loss
AGC_PKC_PKCi_PRKCZ_ST	P35611	ADD1	Q05513	PRKCZ	S358	G361V	361	Missense	distal	3	no	33.099	24.235	EPSD	COSMIC	31.494	Loss
AGC_PKC_PKCi_PRKCZ_ST	P35611	ADD1	Q05513	PRKCZ	S481	G477E	477	Missense	distal	-4	no	37.015	37.206	EPSD	COSMIC	31.494	Up-regulation
AGC_PKC_PKCi_PRKCZ_ST	P35611	ADD1	Q05513	PRKCZ	S481	K474T	474	Missense	distal	-7	no	37.015	33.104	EPSD	COSMIC	31.494	Down-regulation
AGC_PKC_PKCi_PRKCZ_ST	P35611	ADD1	Q05513	PRKCZ	S600	E598G	598	Missense	proximal	-2	no	34.711	39.137	EPSD	COSMIC	31.494	Up-regulation
AGC_PKC_PKCi_PRKCZ_ST	P35611	ADD1	Q05513	PRKCZ	S600	P602S	602	Missense	proximal	2	no	34.711	37.229	EPSD	COSMIC	31.494	Up-regulation
AGC_PKC_PKCi_PRKCZ_ST	P35611	ADD1	Q05513	PRKCZ	S632	T636P	636	Missense	distal	4	no	40.609	38.833	EPSD	COSMIC	31.494	Down-regulation
AGC_PKC_PKCi_PRKCZ_ST	P35611	ADD1	Q05513	PRKCZ	S632	P639H	639	Missense	distal	7	no	40.609	36.803	EPSD	COSMIC	31.494	Down-regulation
AGC_PKC_PKCi_PRKCZ_ST	P35611	ADD1	Q05513	PRKCZ	T636	P639H	639	Missense	distal	3	no	23.392	33.230	EPSD	COSMIC	31.494	Gain
AGC_PKC_PKCi_PRKCZ_ST	P35611	ADD1	Q05513	PRKCZ	S710	G709V	709	Missense	proximal	-1	no	34.885	34.006	EPSD	COSMIC	31.494	Down-regulation
AGC_PKC_PKCi_PRKCZ_ST	P35611	ADD1	Q05513	PRKCZ	S710	S710F	710	Missense	central	0	yes	34.885	0.000	EPSD	COSMIC	31.494	Loss
AGC_PKC_PKCi_PRKCZ_ST	P35611	ADD1	Q05513	PRKCZ	S710	A703V	703	Missense	distal	-7	no	34.885	30.942	EPSD	COSMIC	31.494	Loss
AGC_PKC_PKCi_PRKCZ_ST	P35611	ADD1	Q05513	PRKCZ	S710	G712D	712	Missense	proximal	2	no	34.885	40.094	EPSD	COSMIC	31.494	Up-regulation
AGC_PKC_PKCi_PRKCZ_ST	P35611	ADD1	Q05513	PRKCZ	S716	G709V	709	Missense	distal	-7	no	32.842	31.349	EPSD	COSMIC	31.494	Loss
AGC_PKC_PKCi_PRKCZ_ST	P35611	ADD1	Q05513	PRKCZ	S716	S710F	710	Missense	distal	-6	no	32.842	32.946	EPSD	COSMIC	31.494	Up-regulation
AGC_PKC_PKCi_PRKCZ_ST	P35611	ADD1	Q05513	PRKCZ	S716	G712D	712	Missense	distal	-4	no	32.842	32.982	EPSD	COSMIC	31.494	Up-regulation
AGC_PKC_PKCi_PRKCZ_ST	P35611	ADD1	Q05513	PRKCZ	S726	S726L	726	Missense	central	0	yes	67.935	0.000	PhosphoSitePlus	COSMIC	31.494	Loss
AGC_PKC_PKCi_PRKCZ_ST	P35611	ADD1	Q05513	PRKCZ	S731	S726L	726	Missense	distal	-5	no	49.943	51.458	EPSD	COSMIC	31.494	Up-regulation
AGC_PKC_PKCi_PRKCZ_ST	Q9UJZ1	STOML2	Q05513	PRKCZ	S21	R26Q	26	Missense	distal	5	no	37.672	37.044	EPSD	COSMIC	31.494	Down-regulation
AGC_PKC_PKCi_PRKCZ_ST	Q9UJZ1	STOML2	Q05513	PRKCZ	S29	R26Q	26	Missense	distal	-3	no	32.184	20.297	EPSD	COSMIC	31.494	Loss
AGC_PKC_PKCi_PRKCZ_ST	Q9UJZ1	STOML2	Q05513	PRKCZ	S29	S30C	30	Missense	proximal	1	no	32.184	32.307	EPSD	COSMIC	31.494	Up-regulation
AGC_PKC_PKCi_PRKCZ_ST	Q9UJZ1	STOML2	Q05513	PRKCZ	S142	R148Q	148	Missense	distal	6	no	34.784	28.892	EPSD	COSMIC	31.494	Loss
AGC_PKC_PKCi_PRKCZ_ST	Q9UJZ1	STOML2	Q05513	PRKCZ	S142	G139D	139	Missense	distal	-3	no	34.784	40.548	EPSD	COSMIC	31.494	Up-regulation
AGC_PKC_PKCi_PRKCZ_ST	Q9UJZ1	STOML2	Q05513	PRKCZ	S307	D304N	304	Missense	distal	-3	no	31.904	27.484	EPSD	COSMIC	31.494	Loss
AGC_PKC_PKCi_PRKCZ_ST	P55211	CASP9	Q05513	PRKCZ	S195	R192H	192	Missense	distal	-3	no	37.525	29.096	EPSD	COSMIC	31.494	Loss
AGC_PKC_PKCi_PRKCZ_ST	P55211	CASP9	Q05513	PRKCZ	S195	R193C	193	Missense	proximal	-2	no	37.525	23.734	EPSD	COSMIC	31.494	Loss
AGC_PKC_PKCi_PRKCZ_ST	P55211	CASP9	Q05513	PRKCZ	S195	S196Y	196	Missense	proximal	1	no	37.525	37.436	EPSD	COSMIC	31.494	Down-regulation
AGC_PKC_PKCi_PRKCZ_ST	P78563	ADARB1	Q05513	PRKCZ	S26	S26P	26	Missense	central	0	yes	33.331	0.000	EPSD	COSMIC	31.494	Loss
AGC_PKC_PKCi_PRKCZ_ST	P78563	ADARB1	Q05513	PRKCZ	S31	S26P	26	Missense	distal	-5	no	32.318	33.710	EPSD	COSMIC	31.494	Up-regulation
AGC_PKC_PKCi_PRKCZ_ST	P78563	ADARB1	Q05513	PRKCZ	S429	Q427R	427	Missense	proximal	-2	no	36.197	46.184	EPSD	COSMIC	31.494	Up-regulation
AGC_PKC_PKCi_PRKCZ_ST	Q9UIQ6	LNPEP	Q05513	PRKCZ	S73	L77R	77	Missense	distal	4	no	24.070	36.119	EPSD	COSMIC	31.494	Gain
AGC_PKC_PKCi_PRKCZ_ST	Q9UIQ6	LNPEP	Q05513	PRKCZ	S80	L77R	77	Missense	distal	-3	no	37.021	49.338	PhosphoSitePlus	COSMIC	31.494	Up-regulation
AGC_PKC_PKCi_PRKCZ_ST	Q9UIQ6	LNPEP	Q05513	PRKCZ	S80	G78C	78	Missense	proximal	-2	no	37.021	33.924	PhosphoSitePlus	COSMIC	31.494	Down-regulation
AGC_PKC_PKCi_PRKCZ_ST	Q9UIQ6	LNPEP	Q05513	PRKCZ	S80	G87D	87	Missense	distal	7	no	37.021	36.351	PhosphoSitePlus	COSMIC	31.494	Down-regulation
AGC_PKC_PKCi_PRKCZ_ST	Q9UIQ6	LNPEP	Q05513	PRKCZ	S86	G87D	87	Missense	proximal	1	no	41.194	40.791	EPSD	COSMIC	31.494	Down-regulation
AGC_PKC_PKCi_PRKCZ_ST	Q9UIQ6	LNPEP	Q05513	PRKCZ	S91	G87D	87	Missense	distal	-4	no	40.113	40.254	EPSD	COSMIC	31.494	Up-regulation
AGC_PKC_PKCi_PRKCZ_ST	Q15466	NR0B2	Q05513	PRKCZ	T55	H53R	53	Missense	proximal	-2	no	32.103	40.956	PhosphoSitePlus	COSMIC	31.494	Up-regulation
AGC_PKC_PKCi_PRKCZ_ST	P28329	CHAT	Q05513	PRKCZ	T25	R32W	32	Missense	distal	7	no	43.692	46.822	EPSD	COSMIC	31.494	Up-regulation
AGC_PKC_PKCi_PRKCZ_ST	P28329	CHAT	Q05513	PRKCZ	S125	K122N	122	Missense	distal	-3	no	38.571	30.815	EPSD	COSMIC	31.494	Loss
AGC_PKC_PKCi_PRKCZ_ST	P28329	CHAT	Q05513	PRKCZ	S125	A120T	120	Missense	distal	-5	no	38.571	39.914	EPSD	COSMIC	31.494	Up-regulation
AGC_PKC_PKCi_PRKCZ_ST	P28329	CHAT	Q05513	PRKCZ	S125	A120G	120	Missense	distal	-5	no	38.571	39.984	EPSD	COSMIC	31.494	Up-regulation
AGC_PKC_PKCi_PRKCZ_ST	P28329	CHAT	Q05513	PRKCZ	S125	E127D	127	Missense	proximal	2	no	38.571	46.771	EPSD	COSMIC	31.494	Up-regulation
AGC_PKC_PKCi_PRKCZ_ST	P28329	CHAT	Q05513	PRKCZ	S125	S129Y	129	Missense	distal	4	no	38.571	32.991	EPSD	COSMIC	31.494	Down-regulation
AGC_PKC_PKCi_PRKCZ_ST	P28329	CHAT	Q05513	PRKCZ	T373	R375Q	375	Missense	proximal	2	no	42.238	34.369	EPSD	COSMIC	31.494	Down-regulation
AGC_PKC_PKCi_PRKCZ_ST	P28329	CHAT	Q05513	PRKCZ	T373	K370R	370	Missense	distal	-3	no	42.238	47.376	EPSD	COSMIC	31.494	Up-regulation
AGC_PKC_PKCi_PRKCZ_ST	P28329	CHAT	Q05513	PRKCZ	T373	T366M	366	Missense	distal	-7	no	42.238	43.433	EPSD	COSMIC	31.494	Up-regulation
AGC_PKC_PKCi_PRKCZ_ST	P28329	CHAT	Q05513	PRKCZ	T373	V369M	369	Missense	distal	-4	no	42.238	41.832	EPSD	COSMIC	31.494	Down-regulation
AGC_PKC_PKCi_PRKCZ_ST	P28329	CHAT	Q05513	PRKCZ	T373	D376G	376	Missense	distal	3	no	42.238	43.752	EPSD	COSMIC	31.494	Up-regulation
AGC_PKC_PKCi_PRKCZ_ST	P28329	CHAT	Q05513	PRKCZ	S377	R375Q	375	Missense	proximal	-2	no	38.172	28.185	EPSD	COSMIC	31.494	Loss
AGC_PKC_PKCi_PRKCZ_ST	P28329	CHAT	Q05513	PRKCZ	S377	R383S	383	Missense	distal	6	no	38.172	33.759	EPSD	COSMIC	31.494	Down-regulation
AGC_PKC_PKCi_PRKCZ_ST	P28329	CHAT	Q05513	PRKCZ	S377	K370R	370	Missense	distal	-7	no	38.172	38.615	EPSD	COSMIC	31.494	Up-regulation
AGC_PKC_PKCi_PRKCZ_ST	P28329	CHAT	Q05513	PRKCZ	S377	R383C	383	Missense	distal	6	no	38.172	31.161	EPSD	COSMIC	31.494	Loss
AGC_PKC_PKCi_PRKCZ_ST	P28329	CHAT	Q05513	PRKCZ	S377	D376G	376	Missense	proximal	-1	no	38.172	38.690	EPSD	COSMIC	31.494	Up-regulation
AGC_PKC_PKCi_PRKCZ_ST	P28329	CHAT	Q05513	PRKCZ	S377	R383H	383	Missense	distal	6	no	38.172	37.129	EPSD	COSMIC	31.494	Down-regulation
AGC_PKC_PKCi_PRKCZ_ST	P28329	CHAT	Q05513	PRKCZ	S465	R466Q	466	Missense	proximal	1	no	35.215	32.942	EPSD	COSMIC	31.494	Down-regulation
AGC_PKC_PKCi_PRKCZ_ST	P28329	CHAT	Q05513	PRKCZ	S465	R466L	466	Missense	proximal	1	no	35.215	33.083	EPSD	COSMIC	31.494	Down-regulation
AGC_PKC_PKCi_PRKCZ_ST	P28329	CHAT	Q05513	PRKCZ	S558	E555K	555	Missense	distal	-3	no	30.107	43.402	EPSD	COSMIC	31.494	Gain
AGC_PKC_PKCi_PRKCZ_ST	P28329	CHAT	Q05513	PRKCZ	S558	V551A	551	Missense	distal	-7	no	30.107	34.050	EPSD	COSMIC	31.494	Gain
AGC_PKC_PKCi_PRKCZ_ST	P46937	YAP1	Q05513	PRKCZ	S105	R106G	106	Missense	proximal	1	no	34.124	32.411	EPSD	COSMIC	31.494	Down-regulation
AGC_PKC_PKCi_PRKCZ_ST	P46937	YAP1	Q05513	PRKCZ	S105	S105P	105	Missense	central	0	yes	34.124	0.000	EPSD	COSMIC	31.494	Loss
AGC_PKC_PKCi_PRKCZ_ST	P46937	YAP1	Q05513	PRKCZ	S105	K102R	102	Missense	distal	-3	no	34.124	39.262	EPSD	COSMIC	31.494	Up-regulation
AGC_PKC_PKCi_PRKCZ_ST	P46937	YAP1	Q05513	PRKCZ	S109	R106G	106	Missense	distal	-3	no	47.612	33.374	EPSD;PhosphoSitePlus	COSMIC	31.494	Down-regulation
AGC_PKC_PKCi_PRKCZ_ST	P46937	YAP1	Q05513	PRKCZ	S109	S105P	105	Missense	distal	-4	no	47.612	48.010	EPSD;PhosphoSitePlus	COSMIC	31.494	Up-regulation
AGC_PKC_PKCi_PRKCZ_ST	P46937	YAP1	Q05513	PRKCZ	S109	K102R	102	Missense	distal	-7	no	47.612	48.054	EPSD;PhosphoSitePlus	COSMIC	31.494	Up-regulation
AGC_PKC_PKCi_PRKCZ_ST	P46937	YAP1	Q05513	PRKCZ	S164	Q162R	162	Missense	proximal	-2	no	22.955	32.942	EPSD	COSMIC	31.494	Gain
AGC_PKC_PKCi_PRKCZ_ST	P46937	YAP1	Q05513	PRKCZ	S184	A180T	180	Missense	distal	-4	no	34.757	34.804	EPSD	COSMIC	31.494	Up-regulation
AGC_PKC_PKCi_PRKCZ_ST	P46937	YAP1	Q05513	PRKCZ	S274	P278S	278	Missense	distal	4	no	27.782	34.818	EPSD	COSMIC	31.494	Gain
AGC_PKC_PKCi_PRKCZ_ST	P46937	YAP1	Q05513	PRKCZ	S274	S276R	276	Missense	proximal	2	no	27.782	37.809	EPSD	COSMIC	31.494	Gain
AGC_PKC_PKCi_PRKCZ_ST	P46937	YAP1	Q05513	PRKCZ	S393	E396K	396	Missense	distal	3	no	25.470	34.913	EPSD	COSMIC	31.494	Gain
AGC_PKC_PKCi_PRKCZ_ST	P46937	YAP1	Q05513	PRKCZ	S397	D399G	399	Missense	proximal	2	no	36.276	31.067	EPSD	COSMIC	31.494	Loss
AGC_PKC_PKCi_PRKCZ_ST	P46937	YAP1	Q05513	PRKCZ	S397	T390I	390	Missense	distal	-7	no	36.276	33.174	EPSD	COSMIC	31.494	Down-regulation
AGC_PKC_PKCi_PRKCZ_ST	P46937	YAP1	Q05513	PRKCZ	S397	E396K	396	Missense	proximal	-1	no	36.276	37.390	EPSD	COSMIC	31.494	Up-regulation
AGC_PKC_PKCi_PRKCZ_ST	P46937	YAP1	Q05513	PRKCZ	S397	D399H	399	Missense	proximal	2	no	36.276	36.072	EPSD	COSMIC	31.494	Down-regulation
AGC_PKC_PKCi_PRKCZ_ST	P46937	YAP1	Q05513	PRKCZ	S397	D395G	395	Missense	proximal	-2	no	36.276	32.295	EPSD	COSMIC	31.494	Down-regulation
AGC_PKC_PKCi_PRKCZ_ST	P46937	YAP1	Q05513	PRKCZ	S408	R411Q	411	Missense	distal	3	no	34.382	28.785	EPSD	COSMIC	31.494	Loss
AGC_PKC_PKCi_PRKCZ_ST	P46937	YAP1	Q05513	PRKCZ	T428	D427H	427	Missense	proximal	-1	no	34.511	34.685	EPSD	COSMIC	31.494	Up-regulation
AGC_PKC_PKCi_PRKCZ_ST	P46937	YAP1	Q05513	PRKCZ	T428	S432C	432	Missense	distal	4	no	34.511	19.581	EPSD	COSMIC	31.494	Loss
AGC_PKC_PKCi_PRKCZ_ST	P46937	YAP1	Q05513	PRKCZ	T428	I429L	429	Missense	proximal	1	no	34.511	33.827	EPSD	COSMIC	31.494	Down-regulation
AGC_PKC_PKCi_PRKCZ_ST	P46937	YAP1	Q05513	PRKCZ	T428	P435L	435	Missense	distal	7	no	34.511	31.981	EPSD	COSMIC	31.494	Down-regulation
AGC_PKC_PKCi_PRKCZ_ST	P46937	YAP1	Q05513	PRKCZ	S499	L501I	501	Missense	proximal	2	no	38.495	33.315	EPSD	COSMIC	31.494	Down-regulation
AGC_PKC_PKCi_PRKCZ_ST	Q5JVS0	HABP4	Q05513	PRKCZ	T354	N360H	360	Missense	distal	6	no	30.770	33.509	EPSD;PhosphoSitePlus	COSMIC	31.494	Gain
AGC_PKC_PKCi_PRKCZ_ST	Q5JVS0	HABP4	Q05513	PRKCZ	T375	R379Q	379	Missense	distal	4	no	43.427	40.210	PhosphoSitePlus;EPSD	COSMIC	31.494	Down-regulation
AGC_PKC_PKCi_PRKCZ_ST	Q5JVS0	HABP4	Q05513	PRKCZ	T375	R379W	379	Missense	distal	4	no	43.427	29.556	PhosphoSitePlus;EPSD	COSMIC;GDSC	31.494	Loss
AGC_PKC_PKCi_PRKCZ_ST	Q5JVS0	HABP4	Q05513	PRKCZ	T375	G377A	377	Missense	proximal	2	no	43.427	45.259	PhosphoSitePlus;EPSD	COSMIC	31.494	Up-regulation
AGC_PKC_PKCi_PRKCZ_ST	O14920	IKBKB	Q05513	PRKCZ	S177	E172G	172	Missense	distal	-5	no	38.061	37.568	PhosphoSitePlus;EPSD	COSMIC	31.494	Down-regulation
AGC_PKC_PKCi_PRKCZ_ST	O14920	IKBKB	Q05513	PRKCZ	S177	K171E	171	Missense	distal	-6	no	38.061	38.504	PhosphoSitePlus;EPSD	COSMIC;CCLE	31.494	Up-regulation
AGC_PKC_PKCi_PRKCZ_ST	O14920	IKBKB	Q05513	PRKCZ	S177	A170T	170	Missense	distal	-7	no	38.061	35.932	PhosphoSitePlus;EPSD	COSMIC	31.494	Down-regulation
AGC_PKC_PKCi_PRKCZ_ST	O14920	IKBKB	Q05513	PRKCZ	S177	K171T	171	Missense	distal	-6	no	38.061	38.214	PhosphoSitePlus;EPSD	COSMIC	31.494	Up-regulation
AGC_PKC_PKCi_PRKCZ_ST	O14920	IKBKB	Q05513	PRKCZ	S177	K171M	171	Missense	distal	-6	no	38.061	38.174	PhosphoSitePlus;EPSD	COSMIC	31.494	Up-regulation
AGC_PKC_PKCi_PRKCZ_ST	O14920	IKBKB	Q05513	PRKCZ	S177	K171Q	171	Missense	distal	-6	no	38.061	38.239	PhosphoSitePlus;EPSD	COSMIC	31.494	Up-regulation
AGC_PKC_PKCi_PRKCZ_ST	O14920	IKBKB	Q05513	PRKCZ	S267	N264K	264	Missense	distal	-3	no	30.572	38.329	EPSD	COSMIC	31.494	Gain
AGC_PKC_PKCi_PRKCZ_ST	O14920	IKBKB	Q05513	PRKCZ	S267	N264H	264	Missense	distal	-3	no	30.572	35.038	EPSD	COSMIC	31.494	Gain
AGC_PKC_PKCi_PRKCZ_ST	Q8IX03	WWC1	Q05513	PRKCZ	S793	S793N	793	Missense	central	0	yes	34.090	0.000	EPSD	COSMIC	31.494	Loss
AGC_PKC_PKCi_PRKCZ_ST	Q8IX03	WWC1	Q05513	PRKCZ	S876	E873K	873	Missense	distal	-3	no	23.834	37.129	EPSD	COSMIC	31.494	Gain
AGC_PKC_PKCi_PRKCZ_ST	Q8IX03	WWC1	Q05513	PRKCZ	T923	K928Q	928	Missense	distal	5	no	31.551	31.289	EPSD	COSMIC	31.494	Loss
AGC_PKC_PKCi_PRKCZ_ST	Q8IX03	WWC1	Q05513	PRKCZ	S947	T951I	951	Missense	distal	4	no	32.425	30.565	EPSD	COSMIC	31.494	Loss
AGC_PKC_PKCi_PRKCZ_ST	Q8IX03	WWC1	Q05513	PRKCZ	S962	R966P	966	Missense	distal	4	no	43.096	34.833	EPSD	COSMIC	31.494	Down-regulation
AGC_PKC_PKCi_PRKCZ_ST	Q8IX03	WWC1	Q05513	PRKCZ	S974	S981F	981	Missense	distal	7	no	37.061	38.357	EPSD	COSMIC	31.494	Up-regulation
AGC_PKC_PKCi_PRKCZ_ST	Q8IX03	WWC1	Q05513	PRKCZ	S974	M970I	970	Missense	distal	-4	no	37.061	37.362	EPSD	COSMIC	31.494	Up-regulation
AGC_PKC_PKCi_PRKCZ_ST	Q8IX03	WWC1	Q05513	PRKCZ	S974	S981L	981	Missense	distal	7	no	37.061	37.840	EPSD	COSMIC	31.494	Up-regulation
AGC_PKC_PKCi_PRKCZ_ST	Q8IX03	WWC1	Q05513	PRKCZ	S978	S981F	981	Missense	distal	3	no	37.486	30.432	PhosphoSitePlus;EPSD	COSMIC	31.494	Loss
AGC_PKC_PKCi_PRKCZ_ST	Q8IX03	WWC1	Q05513	PRKCZ	S978	S981L	981	Missense	distal	3	no	37.486	38.764	PhosphoSitePlus;EPSD	COSMIC	31.494	Up-regulation
AGC_PKC_PKCi_PRKCZ_ST	Q16612	NREP	Q05513	PRKCZ	S59	S59F	59	Missense	central	0	yes	36.358	0.000	PhosphoSitePlus	COSMIC	31.494	Loss
AGC_PKC_PKCi_PRKCZ_ST	Q16612	NREP	Q05513	PRKCZ	S59	H66Y	66	Missense	distal	7	no	36.358	39.218	PhosphoSitePlus	COSMIC	31.494	Up-regulation
AGC_PKC_PKCi_PRKCZ_ST	Q16612	NREP	Q05513	PRKCZ	S59	P60T	60	Missense	proximal	1	no	36.358	36.012	PhosphoSitePlus	COSMIC	31.494	Down-regulation
AGC_PKC_PKCi_PRKCZ_ST	Q16612	NREP	Q05513	PRKCZ	S59	L65R	65	Missense	distal	6	no	36.358	40.551	PhosphoSitePlus	COSMIC	31.494	Up-regulation
AGC_PKC_PKCi_PRKCZ_ST	P55040	GEM	Q05513	PRKCZ	T12	Q10H	10	Missense	proximal	-2	no	39.531	40.665	EPSD	COSMIC	31.494	Up-regulation
AGC_PKC_PKCi_PRKCZ_ST	P55040	GEM	Q05513	PRKCZ	T12	G11C	11	Missense	proximal	-1	no	39.531	38.047	EPSD	COSMIC	31.494	Down-regulation
AGC_PKC_PKCi_PRKCZ_ST	P55040	GEM	Q05513	PRKCZ	T12	G14D	14	Missense	proximal	2	no	39.531	44.740	EPSD	COSMIC;GDSC;CCLE	31.494	Up-regulation
AGC_PKC_PKCi_PRKCZ_ST	P55040	GEM	Q05513	PRKCZ	T49	R43C	43	Missense	distal	-6	no	31.274	31.884	EPSD	COSMIC;GDSC	31.494	Gain
AGC_PKC_PKCi_PRKCZ_ST	P55040	GEM	Q05513	PRKCZ	T49	R43H	43	Missense	distal	-6	no	31.274	31.618	EPSD	COSMIC	31.494	Gain
AGC_PKC_PKCi_PRKCZ_ST	P55040	GEM	Q05513	PRKCZ	S261	R268L	268	Missense	distal	7	no	45.568	46.304	PhosphoSitePlus	COSMIC	31.494	Up-regulation
AGC_PKC_PKCi_PRKCZ_ST	P55040	GEM	Q05513	PRKCZ	S287	L285F	285	Missense	proximal	-2	no	32.483	29.735	EPSD	COSMIC	31.494	Loss
AGC_PKC_PKCi_PRKCZ_ST	P55040	GEM	Q05513	PRKCZ	S287	L285I	285	Missense	proximal	-2	no	32.483	27.821	EPSD	COSMIC;GDSC;CCLE	31.494	Loss
AGC_PKC_PKCi_PRKCZ_ST	P55040	GEM	Q05513	PRKCZ	S287	C290Y	290	Missense	distal	3	no	32.483	35.617	EPSD	COSMIC;GDSC;CCLE	31.494	Up-regulation
AGC_PKC_PKCi_PRKCZ_ST	P55040	GEM	Q05513	PRKCZ	S289	L285F	285	Missense	distal	-4	no	41.537	41.388	EPSD	COSMIC	31.494	Down-regulation
AGC_PKC_PKCi_PRKCZ_ST	P55040	GEM	Q05513	PRKCZ	S289	L285I	285	Missense	distal	-4	no	41.537	41.356	EPSD	COSMIC;GDSC;CCLE	31.494	Down-regulation
AGC_PKC_PKCi_PRKCZ_ST	P55040	GEM	Q05513	PRKCZ	S289	C290Y	290	Missense	proximal	1	no	41.537	41.325	EPSD	COSMIC;GDSC;CCLE	31.494	Down-regulation
AGC_PKC_PKCi_PRKCZ_ST	Q12933	TRAF2	Q05513	PRKCZ	S55	C57Y	57	Missense	proximal	2	no	34.062	35.234	PhosphoSitePlus	COSMIC	31.494	Up-regulation
AGC_PKC_PKCi_PRKCZ_ST	Q12933	TRAF2	Q05513	PRKCZ	S55	H51R	51	Missense	distal	-4	no	34.062	33.847	PhosphoSitePlus	COSMIC	31.494	Down-regulation
AGC_PKC_PKCi_PRKCZ_ST	Q12933	TRAF2	Q05513	PRKCZ	S162	H165Y	165	Missense	distal	3	no	37.114	31.417	EPSD	COSMIC	31.494	Loss
AGC_PKC_PKCi_PRKCZ_ST	Q12933	TRAF2	Q05513	PRKCZ	S262	A264T	264	Missense	proximal	2	no	33.818	32.206	EPSD	COSMIC	31.494	Down-regulation
AGC_PKC_PKCi_PRKCZ_ST	Q12933	TRAF2	Q05513	PRKCZ	S262	S266P	266	Missense	distal	4	no	33.818	26.781	EPSD	COSMIC	31.494	Loss
AGC_PKC_PKCi_PRKCZ_ST	Q12933	TRAF2	Q05513	PRKCZ	S262	P256L	256	Missense	distal	-6	no	33.818	33.566	EPSD	COSMIC	31.494	Down-regulation
AGC_PKC_PKCi_PRKCZ_ST	Q12933	TRAF2	Q05513	PRKCZ	S274	A280T	280	Missense	distal	6	no	37.917	34.973	EPSD	COSMIC	31.494	Down-regulation
AGC_PKC_PKCi_PRKCZ_ST	Q12933	TRAF2	Q05513	PRKCZ	S274	S274I	274	Missense	central	0	yes	37.917	0.000	EPSD	COSMIC	31.494	Loss
AGC_PKC_PKCi_PRKCZ_ST	Q12933	TRAF2	Q05513	PRKCZ	S274	E273K	273	Missense	proximal	-1	no	37.917	39.031	EPSD	COSMIC;GDSC;CCLE	31.494	Up-regulation
AGC_PKC_PKCi_PRKCZ_ST	Q12933	TRAF2	Q05513	PRKCZ	T401	I394M	394	Missense	distal	-7	no	27.801	32.098	EPSD	COSMIC	31.494	Gain
AGC_PKC_PKCi_PRKCZ_ST	P14598	NCF1	Q05513	PRKCZ	S288	V287A	287	Missense	proximal	-1	no	31.117	32.041	EPSD	COSMIC	31.494	Gain
AGC_PKC_PKCi_PRKCZ_ST	P14598	NCF1	Q05513	PRKCZ	T356	P349R	349	Missense	distal	-7	no	32.913	39.907	EPSD	COSMIC	31.494	Up-regulation
AGC_PKC_PKCi_PRKCZ_ST	Q04206	RELA	Q05513	PRKCZ	S131	R124W	124	Missense	distal	-7	no	36.152	28.001	EPSD	COSMIC	31.494	Loss
AGC_PKC_PKCi_PRKCZ_ST	Q04206	RELA	Q05513	PRKCZ	S238	S240L	240	Missense	proximal	2	no	40.708	43.267	EPSD	COSMIC	31.494	Up-regulation
AGC_PKC_PKCi_PRKCZ_ST	Q04206	RELA	Q05513	PRKCZ	S269	R267C	267	Missense	proximal	-2	no	36.479	22.688	EPSD	COSMIC	31.494	Loss
AGC_PKC_PKCi_PRKCZ_ST	Q04206	RELA	Q05513	PRKCZ	S269	R274Q	274	Missense	distal	5	no	36.479	35.851	EPSD	COSMIC	31.494	Down-regulation
AGC_PKC_PKCi_PRKCZ_ST	Q04206	RELA	Q05513	PRKCZ	S276	D277N	277	Missense	proximal	1	no	44.397	44.599	EPSD	COSMIC;CCLE	31.494	Up-regulation
AGC_PKC_PKCi_PRKCZ_ST	Q04206	RELA	Q05513	PRKCZ	S276	R274Q	274	Missense	proximal	-2	no	44.397	34.411	EPSD	COSMIC	31.494	Down-regulation
AGC_PKC_PKCi_PRKCZ_ST	Q04206	RELA	Q05513	PRKCZ	S276	R278Q	278	Missense	proximal	2	no	44.397	36.528	EPSD	COSMIC	31.494	Down-regulation
AGC_PKC_PKCi_PRKCZ_ST	Q04206	RELA	Q05513	PRKCZ	S311	M313I	313	Missense	proximal	2	no	37.373	31.497	PhosphoSitePlus	COSMIC	31.494	Down-regulation
AGC_PKC_PKCi_PRKCZ_ST	Q04206	RELA	Q05513	PRKCZ	S311	K314N	314	Missense	distal	3	no	37.373	30.788	PhosphoSitePlus	COSMIC	31.494	Loss
AGC_PKC_PKCi_PRKCZ_ST	Q04206	RELA	Q05513	PRKCZ	S311	T305A	305	Missense	distal	-6	no	37.373	37.226	PhosphoSitePlus	COSMIC	31.494	Down-regulation
AGC_PKC_PKCi_PRKCZ_ST	Q04206	RELA	Q05513	PRKCZ	T505	E498V	498	Missense	distal	-7	no	44.864	44.959	EPSD	COSMIC	31.494	Up-regulation
AGC_PKC_PKCi_PRKCZ_ST	Q04206	RELA	Q05513	PRKCZ	T505	R502P	502	Missense	distal	-3	no	44.864	25.993	EPSD	COSMIC	31.494	Loss
AGC_PKC_PKCi_PRKCZ_ST	Q04206	RELA	Q05513	PRKCZ	T505	T501I	501	Missense	distal	-4	no	44.864	45.131	EPSD	COSMIC	31.494	Up-regulation
AGC_PKC_PKCi_PRKCZ_ST	Q04206	RELA	Q05513	PRKCZ	T505	A499T	499	Missense	distal	-6	no	44.864	45.011	EPSD	COSMIC	31.494	Up-regulation
AGC_PKC_PKCi_PRKCZ_ST	Q04206	RELA	Q05513	PRKCZ	S536	F534L	534	Missense	proximal	-2	no	42.930	45.677	EPSD	COSMIC	31.494	Up-regulation
AGC_PKC_PKCi_PRKCZ_ST	Q16236	NFE2L2	Q05513	PRKCZ	S40	F37S	37	Missense	distal	-3	no	30.141	31.737	PhosphoSitePlus	COSMIC	31.494	Gain
AGC_PKC_PKCi_PRKCZ_ST	Q16236	NFE2L2	Q05513	PRKCZ	S40	S33R	33	Missense	distal	-7	no	30.141	35.293	PhosphoSitePlus	COSMIC	31.494	Gain
AGC_PKC_PKCi_PRKCZ_ST	Q16236	NFE2L2	Q05513	PRKCZ	S40	F37L	37	Missense	distal	-3	no	30.141	32.846	PhosphoSitePlus	COSMIC	31.494	Gain
AGC_PKC_PKCi_PRKCZ_ST	Q16236	NFE2L2	Q05513	PRKCZ	S400	V404A	404	Missense	distal	4	no	23.285	33.457	EPSD	COSMIC	31.494	Gain
AGC_PKC_PKCi_PRKCZ_ST	Q16236	NFE2L2	Q05513	PRKCZ	S447	H446Q	446	Missense	proximal	-1	no	49.201	48.837	EPSD	COSMIC	31.494	Down-regulation
AGC_PKC_PKCi_PRKCZ_ST	Q16236	NFE2L2	Q05513	PRKCZ	S447	D444H	444	Missense	distal	-3	no	49.201	49.246	EPSD	COSMIC	31.494	Up-regulation
Other_PLK_PLK2_PLK3_ST	P15336	ATF2	Q9H4B4	PLK3	T52	K48R	48	Missense	distal	-4	no	10.293	10.644	EPSD	COSMIC	8.404	Up-regulation
Other_PLK_PLK2_PLK3_ST	P15336	ATF2	Q9H4B4	PLK3	T52	M51I	51	Missense	proximal	-1	no	10.293	11.367	EPSD	COSMIC	8.404	Up-regulation
Other_PLK_PLK2_PLK3_ST	P15336	ATF2	Q9H4B4	PLK3	T52	H45N	45	Missense	distal	-7	no	10.293	10.023	EPSD	COSMIC	8.404	Down-regulation
Other_PLK_PLK2_PLK3_ST	P15336	ATF2	Q9H4B4	PLK3	T52	R59C	59	Missense	distal	7	no	10.293	9.621	EPSD	COSMIC	8.404	Down-regulation
Other_PLK_PLK2_PLK3_ST	P15336	ATF2	Q9H4B4	PLK3	T52	G56V	56	Missense	distal	4	no	10.293	9.664	EPSD	COSMIC	8.404	Down-regulation
Other_PLK_PLK2_PLK3_ST	P15336	ATF2	Q9H4B4	PLK3	T69	T73A	73	Missense	distal	4	no	16.687	17.501	PhosphoSitePlus;EPSD	COSMIC	8.404	Up-regulation
Other_PLK_PLK2_PLK3_ST	P15336	ATF2	Q9H4B4	PLK3	T69	F75L	75	Missense	distal	6	no	16.687	16.458	PhosphoSitePlus;EPSD	COSMIC	8.404	Down-regulation
Other_PLK_PLK2_PLK3_ST	P15336	ATF2	Q9H4B4	PLK3	T69	R74T	74	Missense	distal	5	no	16.687	15.923	PhosphoSitePlus;EPSD	COSMIC	8.404	Down-regulation
Other_PLK_PLK2_PLK3_ST	P15336	ATF2	Q9H4B4	PLK3	T69	I64V	64	Missense	distal	-5	no	16.687	15.314	PhosphoSitePlus;EPSD	COSMIC	8.404	Down-regulation
Other_PLK_PLK2_PLK3_ST	P15336	ATF2	Q9H4B4	PLK3	T69	D67E	67	Missense	proximal	-2	no	16.687	19.753	PhosphoSitePlus;EPSD	COSMIC	8.404	Up-regulation
Other_PLK_PLK2_PLK3_ST	P15336	ATF2	Q9H4B4	PLK3	T71	T73A	73	Missense	proximal	2	no	15.978	14.826	EPSD;PhosphoSitePlus	COSMIC	8.404	Down-regulation
Other_PLK_PLK2_PLK3_ST	P15336	ATF2	Q9H4B4	PLK3	T71	F75L	75	Missense	distal	4	no	15.978	15.229	EPSD;PhosphoSitePlus	COSMIC	8.404	Down-regulation
Other_PLK_PLK2_PLK3_ST	P15336	ATF2	Q9H4B4	PLK3	T71	R74T	74	Missense	distal	3	no	15.978	16.728	EPSD;PhosphoSitePlus	COSMIC	8.404	Up-regulation
Other_PLK_PLK2_PLK3_ST	P15336	ATF2	Q9H4B4	PLK3	T71	I64V	64	Missense	distal	-7	no	15.978	15.902	EPSD;PhosphoSitePlus	COSMIC	8.404	Down-regulation
Other_PLK_PLK2_PLK3_ST	P15336	ATF2	Q9H4B4	PLK3	T71	D67E	67	Missense	distal	-4	no	15.978	14.117	EPSD;PhosphoSitePlus	COSMIC	8.404	Down-regulation
Other_PLK_PLK2_PLK3_ST	P15336	ATF2	Q9H4B4	PLK3	S100	M107I	107	Missense	distal	7	no	8.696	7.403	EPSD	COSMIC;GDSC;CCLE	8.404	Loss
Other_PLK_PLK2_PLK3_ST	P15336	ATF2	Q9H4B4	PLK3	S100	K105T	105	Missense	distal	5	no	8.696	8.252	EPSD	COSMIC;GDSC;CCLE	8.404	Loss
Other_PLK_PLK2_PLK3_ST	P15336	ATF2	Q9H4B4	PLK3	S100	K106R	106	Missense	distal	6	no	8.696	8.316	EPSD	COSMIC	8.404	Loss
Other_PLK_PLK2_PLK3_ST	P15336	ATF2	Q9H4B4	PLK3	S112	M107I	107	Missense	distal	-5	no	8.645	10.311	EPSD	COSMIC;GDSC;CCLE	8.404	Up-regulation
Other_PLK_PLK2_PLK3_ST	P15336	ATF2	Q9H4B4	PLK3	S112	K105T	105	Missense	distal	-7	no	8.645	8.342	EPSD	COSMIC;GDSC;CCLE	8.404	Loss
Other_PLK_PLK2_PLK3_ST	P15336	ATF2	Q9H4B4	PLK3	S112	K106R	106	Missense	distal	-6	no	8.645	8.450	EPSD	COSMIC	8.404	Down-regulation
Other_PLK_PLK2_PLK3_ST	P15336	ATF2	Q9H4B4	PLK3	S112	D110E	110	Missense	proximal	-2	no	8.645	11.710	EPSD	COSMIC	8.404	Up-regulation
Other_PLK_PLK2_PLK3_ST	P15336	ATF2	Q9H4B4	PLK3	S127	E125K	125	Missense	proximal	-2	no	10.839	5.943	EPSD	COSMIC	8.404	Loss
Other_PLK_PLK2_PLK3_ST	P15336	ATF2	Q9H4B4	PLK3	S127	S127F	127	Missense	central	0	yes	10.839	0.000	EPSD	COSMIC	8.404	Loss
Other_PLK_PLK2_PLK3_ST	P15336	ATF2	Q9H4B4	PLK3	T145	P141T	141	Missense	distal	-4	no	9.265	8.399	EPSD	COSMIC	8.404	Loss
Other_PLK_PLK2_PLK3_ST	P15336	ATF2	Q9H4B4	PLK3	T145	P141L	141	Missense	distal	-4	no	9.265	9.557	EPSD	COSMIC	8.404	Up-regulation
Other_PLK_PLK2_PLK3_ST	P15336	ATF2	Q9H4B4	PLK3	T145	D147Y	147	Missense	proximal	2	no	9.265	7.758	EPSD	COSMIC	8.404	Loss
Other_PLK_PLK2_PLK3_ST	P15336	ATF2	Q9H4B4	PLK3	T145	T144I	144	Missense	proximal	-1	no	9.265	10.570	EPSD	COSMIC	8.404	Up-regulation
Other_PLK_PLK2_PLK3_ST	P15336	ATF2	Q9H4B4	PLK3	S310	T305I	305	Missense	distal	-5	no	9.437	9.959	EPSD	COSMIC	8.404	Up-regulation
Other_PLK_PLK2_PLK3_ST	P15336	ATF2	Q9H4B4	PLK3	S310	R311Q	311	Missense	proximal	1	no	9.437	9.538	EPSD	COSMIC;GDSC;CCLE	8.404	Up-regulation
Other_PLK_PLK2_PLK3_ST	P15336	ATF2	Q9H4B4	PLK3	S310	Q316K	316	Missense	distal	6	no	9.437	9.824	EPSD	COSMIC	8.404	Up-regulation
Other_PLK_PLK2_PLK3_ST	P15336	ATF2	Q9H4B4	PLK3	S310	Q317H	317	Missense	distal	7	no	9.437	8.943	EPSD	COSMIC	8.404	Down-regulation
Other_PLK_PLK2_PLK3_ST	P15336	ATF2	Q9H4B4	PLK3	T322	Q316K	316	Missense	distal	-6	no	8.380	8.687	EPSD	COSMIC	8.404	Gain
Other_PLK_PLK2_PLK3_ST	P15336	ATF2	Q9H4B4	PLK3	T322	Q317H	317	Missense	distal	-5	no	8.380	8.978	EPSD	COSMIC	8.404	Gain
Other_PLK_PLK2_PLK3_ST	P15336	ATF2	Q9H4B4	PLK3	S328	P326T	326	Missense	proximal	-2	no	6.195	8.949	EPSD	COSMIC	8.404	Gain
Other_PLK_PLK2_PLK3_ST	P15336	ATF2	Q9H4B4	PLK3	T336	Q337K	337	Missense	proximal	1	no	8.857	9.056	EPSD	COSMIC	8.404	Up-regulation
Other_PLK_PLK2_PLK3_ST	P15336	ATF2	Q9H4B4	PLK3	T336	Q335H	335	Missense	proximal	-1	no	8.857	9.453	EPSD	COSMIC	8.404	Up-regulation
Other_PLK_PLK2_PLK3_ST	P15336	ATF2	Q9H4B4	PLK3	T336	R343L	343	Missense	distal	7	no	8.857	8.994	EPSD	COSMIC	8.404	Up-regulation
Other_PLK_PLK2_PLK3_ST	P15336	ATF2	Q9H4B4	PLK3	T336	P334S	334	Missense	proximal	-2	no	8.857	9.942	EPSD	COSMIC	8.404	Up-regulation
Other_PLK_PLK2_PLK3_ST	P15336	ATF2	Q9H4B4	PLK3	T336	H331Y	331	Missense	distal	-5	no	8.857	7.828	EPSD	COSMIC	8.404	Loss
Other_PLK_PLK2_PLK3_ST	P15336	ATF2	Q9H4B4	PLK3	T336	R343Q	343	Missense	distal	7	no	8.857	9.078	EPSD	COSMIC	8.404	Up-regulation
Other_PLK_PLK2_PLK3_ST	P15336	ATF2	Q9H4B4	PLK3	S442	S442L	442	Missense	central	0	yes	9.235	0.000	EPSD	COSMIC	8.404	Loss
Other_PLK_PLK2_PLK3_ST	P15336	ATF2	Q9H4B4	PLK3	S442	P444L	444	Missense	proximal	2	no	9.235	9.258	EPSD	COSMIC	8.404	Up-regulation
Other_PLK_PLK2_PLK3_ST	P15336	ATF2	Q9H4B4	PLK3	S442	P444T	444	Missense	proximal	2	no	9.235	10.914	EPSD	COSMIC	8.404	Up-regulation
Other_PLK_PLK2_PLK3_ST	P15336	ATF2	Q9H4B4	PLK3	S442	S437G	437	Missense	distal	-5	no	9.235	9.330	EPSD	COSMIC	8.404	Up-regulation
Other_PLK_PLK2_PLK3_ST	P15336	ATF2	Q9H4B4	PLK3	S442	S442P	442	Missense	central	0	yes	9.235	0.000	EPSD	COSMIC	8.404	Loss
Other_PLK_PLK2_PLK3_ST	P15336	ATF2	Q9H4B4	PLK3	S442	P444Q	444	Missense	proximal	2	no	9.235	9.525	EPSD	COSMIC	8.404	Up-regulation
Other_PLK_PLK2_PLK3_ST	P15336	ATF2	Q9H4B4	PLK3	S442	S437T	437	Missense	distal	-5	no	9.235	9.880	EPSD	COSMIC	8.404	Up-regulation
Other_PLK_PLK2_PLK3_ST	P15336	ATF2	Q9H4B4	PLK3	S458	S455T	455	Missense	distal	-3	no	8.099	9.100	EPSD	COSMIC	8.404	Gain
Other_PLK_PLK2_PLK3_ST	P62258	YWHAE	Q9H4B4	PLK3	T38	V35L	35	Missense	distal	-3	no	10.359	11.405	EPSD	COSMIC;GDSC;CCLE	8.404	Up-regulation
Other_PLK_PLK2_PLK3_ST	P62258	YWHAE	Q9H4B4	PLK3	T38	E36K	36	Missense	proximal	-2	no	10.359	5.463	EPSD	COSMIC	8.404	Loss
Other_PLK_PLK2_PLK3_ST	P62258	YWHAE	Q9H4B4	PLK3	S46	Y49C	49	Missense	distal	3	no	11.599	10.093	EPSD	COSMIC	8.404	Down-regulation
Other_PLK_PLK2_PLK3_ST	P62258	YWHAE	Q9H4B4	PLK3	S46	K50N	50	Missense	distal	4	no	11.599	10.574	EPSD	COSMIC	8.404	Down-regulation
Other_PLK_PLK2_PLK3_ST	P62258	YWHAE	Q9H4B4	PLK3	T208	T208M	208	Missense	central	0	yes	16.671	0.000	PhosphoSitePlus	COSMIC	8.404	Loss
Other_PLK_PLK2_PLK3_ST	P62258	YWHAE	Q9H4B4	PLK3	T208	I203V	203	Missense	distal	-5	no	16.671	15.297	PhosphoSitePlus	COSMIC	8.404	Down-regulation
Other_PLK_PLK2_PLK3_ST	P62258	YWHAE	Q9H4B4	PLK3	T208	A204T	204	Missense	distal	-4	no	16.671	16.105	PhosphoSitePlus	COSMIC	8.404	Down-regulation
Other_PLK_PLK2_PLK3_ST	P62258	YWHAE	Q9H4B4	PLK3	S210	T208M	208	Missense	proximal	-2	no	11.170	10.485	EPSD	COSMIC	8.404	Down-regulation
Other_PLK_PLK2_PLK3_ST	P62258	YWHAE	Q9H4B4	PLK3	S210	I203V	203	Missense	distal	-7	no	11.170	11.093	EPSD	COSMIC	8.404	Down-regulation
Other_PLK_PLK2_PLK3_ST	P62258	YWHAE	Q9H4B4	PLK3	S210	A204T	204	Missense	distal	-6	no	11.170	10.461	EPSD	COSMIC	8.404	Down-regulation
Other_PLK_PLK2_PLK3_ST	P62258	YWHAE	Q9H4B4	PLK3	S213	T208M	208	Missense	distal	-5	no	8.508	7.363	EPSD	COSMIC	8.404	Loss
Other_PLK_PLK2_PLK3_ST	P62258	YWHAE	Q9H4B4	PLK3	S213	I220T	220	Missense	distal	7	no	8.508	9.124	EPSD	COSMIC	8.404	Up-regulation
Other_PLK_PLK2_PLK3_ST	O96017	CHEK2	Q9H4B4	PLK3	T26	V25I	25	Missense	proximal	-1	no	7.523	8.882	EPSD	COSMIC	8.404	Gain
Other_PLK_PLK2_PLK3_ST	O96017	CHEK2	Q9H4B4	PLK3	S62	Q69R	69	Missense	distal	7	no	16.118	15.897	EPSD;PhosphoSitePlus	COSMIC	8.404	Down-regulation
Other_PLK_PLK2_PLK3_ST	O96017	CHEK2	Q9H4B4	PLK3	T65	Q69R	69	Missense	distal	4	no	8.947	8.902	EPSD	COSMIC	8.404	Down-regulation
Other_PLK_PLK2_PLK3_ST	O96017	CHEK2	Q9H4B4	PLK3	S73	Q69R	69	Missense	distal	-4	no	16.249	16.478	PhosphoSitePlus;EPSD	COSMIC	8.404	Up-regulation
Other_PLK_PLK2_PLK3_ST	O96017	CHEK2	Q9H4B4	PLK3	S120	R117M	117	Missense	distal	-3	no	6.377	9.057	EPSD	COSMIC	8.404	Gain
Other_PLK_PLK2_PLK3_ST	O96017	CHEK2	Q9H4B4	PLK3	S140	T133K	133	Missense	distal	-7	no	10.344	10.647	EPSD	COSMIC	8.404	Up-regulation
Other_PLK_PLK2_PLK3_ST	O96017	CHEK2	Q9H4B4	PLK3	S140	R137Q	137	Missense	distal	-3	no	10.344	11.567	EPSD	COSMIC	8.404	Up-regulation
Other_PLK_PLK2_PLK3_ST	O96017	CHEK2	Q9H4B4	PLK3	S140	R145L	145	Missense	distal	5	no	10.344	10.238	EPSD	COSMIC	8.404	Down-regulation
Other_PLK_PLK2_PLK3_ST	O96017	CHEK2	Q9H4B4	PLK3	S140	F144L	144	Missense	distal	4	no	10.344	9.595	EPSD	COSMIC	8.404	Down-regulation
Other_PLK_PLK2_PLK3_ST	O96017	CHEK2	Q9H4B4	PLK3	S164	E161Q	161	Missense	distal	-3	no	11.800	8.796	EPSD	COSMIC	8.404	Down-regulation
Other_PLK_PLK2_PLK3_ST	O96017	CHEK2	Q9H4B4	PLK3	S164	H163D	163	Missense	proximal	-1	no	11.800	11.510	EPSD	COSMIC	8.404	Down-regulation
Other_PLK_PLK2_PLK3_ST	O96017	CHEK2	Q9H4B4	PLK3	S164	T168S	168	Missense	distal	4	no	11.800	12.232	EPSD	COSMIC	8.404	Up-regulation
Other_PLK_PLK2_PLK3_ST	O96017	CHEK2	Q9H4B4	PLK3	S164	S164N	164	Missense	central	0	yes	11.800	0.000	EPSD	COSMIC;CCLE	8.404	Loss
Other_PLK_PLK2_PLK3_ST	O96017	CHEK2	Q9H4B4	PLK3	S164	Y159C	159	Missense	distal	-5	no	11.800	11.494	EPSD	COSMIC	8.404	Down-regulation
Other_PLK_PLK2_PLK3_ST	O96017	CHEK2	Q9H4B4	PLK3	S164	F169L	169	Missense	distal	5	no	11.800	11.374	EPSD	COSMIC;CCLE	8.404	Down-regulation
Other_PLK_PLK2_PLK3_ST	O96017	CHEK2	Q9H4B4	PLK3	S164	V170I	170	Missense	distal	6	no	11.800	12.334	EPSD	COSMIC	8.404	Up-regulation
Other_PLK_PLK2_PLK3_ST	O96017	CHEK2	Q9H4B4	PLK3	S164	I160M	160	Missense	distal	-4	no	11.800	11.614	EPSD	COSMIC	8.404	Down-regulation
Other_PLK_PLK2_PLK3_ST	O96017	CHEK2	Q9H4B4	PLK3	T205	V200I	200	Missense	distal	-5	no	7.261	8.634	EPSD	COSMIC	8.404	Gain
Other_PLK_PLK2_PLK3_ST	O96017	CHEK2	Q9H4B4	PLK3	T225	D218N	218	Missense	distal	-7	no	9.976	9.961	EPSD	COSMIC	8.404	Down-regulation
Other_PLK_PLK2_PLK3_ST	O96017	CHEK2	Q9H4B4	PLK3	T225	A230P	230	Missense	distal	5	no	9.976	10.432	EPSD	COSMIC	8.404	Up-regulation
Other_PLK_PLK2_PLK3_ST	O96017	CHEK2	Q9H4B4	PLK3	T225	A230S	230	Missense	distal	5	no	9.976	10.472	EPSD	COSMIC	8.404	Up-regulation
Other_PLK_PLK2_PLK3_ST	O96017	CHEK2	Q9H4B4	PLK3	T225	A230T	230	Missense	distal	5	no	9.976	9.607	EPSD	COSMIC	8.404	Down-regulation
Other_PLK_PLK2_PLK3_ST	O96017	CHEK2	Q9H4B4	PLK3	S357	D361Y	361	Missense	distal	4	no	9.449	9.530	EPSD	COSMIC	8.404	Up-regulation
Other_PLK_PLK2_PLK3_ST	O96017	CHEK2	Q9H4B4	PLK3	S357	E360Q	360	Missense	distal	3	no	9.449	8.123	EPSD	COSMIC	8.404	Loss
Other_PLK_PLK2_PLK3_ST	O96017	CHEK2	Q9H4B4	PLK3	S357	D361E	361	Missense	distal	4	no	9.449	8.650	EPSD	COSMIC	8.404	Down-regulation
Other_PLK_PLK2_PLK3_ST	O96017	CHEK2	Q9H4B4	PLK3	S357	S356L	356	Missense	proximal	-1	no	9.449	9.601	EPSD	COSMIC	8.404	Up-regulation
Other_PLK_PLK2_PLK3_ST	O96017	CHEK2	Q9H4B4	PLK3	S357	L355P	355	Missense	proximal	-2	no	9.449	7.285	EPSD	COSMIC;CCLE	8.404	Loss
Other_PLK_PLK2_PLK3_ST	O96017	CHEK2	Q9H4B4	PLK3	T387	A392S	392	Missense	distal	5	no	8.352	8.847	EPSD	COSMIC	8.404	Gain
Other_PLK_PLK2_PLK3_ST	O96017	CHEK2	Q9H4B4	PLK3	T441	I448S	448	Missense	distal	7	no	9.441	10.843	EPSD	COSMIC	8.404	Up-regulation
Other_PLK_PLK2_PLK3_ST	O96017	CHEK2	Q9H4B4	PLK3	T441	K437Q	437	Missense	distal	-4	no	9.441	9.564	EPSD	COSMIC	8.404	Up-regulation
Other_PLK_PLK2_PLK3_ST	O96017	CHEK2	Q9H4B4	PLK3	T441	I448T	448	Missense	distal	7	no	9.441	10.058	EPSD	COSMIC	8.404	Up-regulation
Other_PLK_PLK2_PLK3_ST	O96017	CHEK2	Q9H4B4	PLK3	T441	T441I	441	Missense	central	0	yes	9.441	0.000	EPSD	COSMIC	8.404	Loss
Other_PLK_PLK2_PLK3_ST	O96017	CHEK2	Q9H4B4	PLK3	T441	G443V	443	Missense	proximal	2	no	9.441	9.272	EPSD	COSMIC	8.404	Down-regulation
Other_PLK_PLK2_PLK3_ST	O96017	CHEK2	Q9H4B4	PLK3	S456	E457K	457	Missense	proximal	1	no	7.930	9.015	EPSD	COSMIC	8.404	Gain
Other_PLK_PLK2_PLK3_ST	O96017	CHEK2	Q9H4B4	PLK3	S456	V451L	451	Missense	distal	-5	no	7.930	8.531	EPSD	COSMIC	8.404	Gain
Other_PLK_PLK2_PLK3_ST	P11388	TOP2A	Q9H4B4	PLK3	S812	L817V	817	Missense	distal	5	no	9.560	9.076	EPSD	COSMIC	8.404	Down-regulation
Other_PLK_PLK2_PLK3_ST	P11388	TOP2A	Q9H4B4	PLK3	S812	M809V	809	Missense	distal	-3	no	9.560	7.684	EPSD	COSMIC	8.404	Loss
Other_PLK_PLK2_PLK3_ST	P11388	TOP2A	Q9H4B4	PLK3	T825	H824Q	824	Missense	proximal	-1	no	10.489	9.892	EPSD	COSMIC	8.404	Down-regulation
Other_PLK_PLK2_PLK3_ST	P11388	TOP2A	Q9H4B4	PLK3	T898	K893N	893	Missense	distal	-5	no	8.855	8.125	EPSD	COSMIC	8.404	Loss
Other_PLK_PLK2_PLK3_ST	P11388	TOP2A	Q9H4B4	PLK3	T950	T947I	947	Missense	distal	-3	no	9.241	4.420	EPSD	COSMIC	8.404	Loss
Other_PLK_PLK2_PLK3_ST	P11388	TOP2A	Q9H4B4	PLK3	T950	T947A	947	Missense	distal	-3	no	9.241	8.903	EPSD	COSMIC	8.404	Down-regulation
Other_PLK_PLK2_PLK3_ST	P11388	TOP2A	Q9H4B4	PLK3	T950	T950A	950	Missense	central	0	yes	9.241	0.000	EPSD	COSMIC	8.404	Loss
Other_PLK_PLK2_PLK3_ST	P11388	TOP2A	Q9H4B4	PLK3	S1106	K1110E	1110	Missense	distal	4	no	9.872	8.647	EPSD	COSMIC;GDSC	8.404	Down-regulation
Other_PLK_PLK2_PLK3_ST	P11388	TOP2A	Q9H4B4	PLK3	S1115	K1110E	1110	Missense	distal	-5	no	10.674	9.434	EPSD	COSMIC;GDSC	8.404	Down-regulation
Other_PLK_PLK2_PLK3_ST	P11388	TOP2A	Q9H4B4	PLK3	S1121	Y1127C	1127	Missense	distal	6	no	11.717	12.207	EPSD	COSMIC	8.404	Up-regulation
Other_PLK_PLK2_PLK3_ST	P11388	TOP2A	Q9H4B4	PLK3	S1247	E1242K	1242	Missense	distal	-5	no	7.538	8.778	EPSD	COSMIC	8.404	Gain
Other_PLK_PLK2_PLK3_ST	P11388	TOP2A	Q9H4B4	PLK3	T1272	K1276T	1276	Missense	distal	4	no	10.675	10.012	EPSD	COSMIC	8.404	Down-regulation
Other_PLK_PLK2_PLK3_ST	P11388	TOP2A	Q9H4B4	PLK3	S1302	D1304G	1304	Missense	proximal	2	no	10.669	9.092	EPSD	COSMIC	8.404	Down-regulation
Other_PLK_PLK2_PLK3_ST	P11388	TOP2A	Q9H4B4	PLK3	S1377	D1383N	1383	Missense	distal	6	no	10.867	10.219	EPSD	COSMIC	8.404	Down-regulation
Other_PLK_PLK2_PLK3_ST	P11388	TOP2A	Q9H4B4	PLK3	S1393	V1388L	1388	Missense	distal	-5	no	9.666	10.266	EPSD	COSMIC	8.404	Up-regulation
Other_PLK_PLK2_PLK3_ST	P11388	TOP2A	Q9H4B4	PLK3	T1470	R1463C	1463	Missense	distal	-7	no	10.946	10.899	EPSD	COSMIC;GDSC;CCLE	8.404	Down-regulation
Other_PLK_PLK2_PLK3_ST	P11388	TOP2A	Q9H4B4	PLK3	T1470	R1464H	1464	Missense	distal	-6	no	10.946	11.828	EPSD	COSMIC	8.404	Up-regulation
Other_PLK_PLK2_PLK3_ST	P60484	PTEN	Q9H4B4	PLK3	S294	S294R	294	Missense	central	0	yes	11.776	0.000	EPSD	COSMIC	8.404	Loss
Other_PLK_PLK2_PLK3_ST	P60484	PTEN	Q9H4B4	PLK3	S294	G293V	293	Missense	proximal	-1	no	11.776	10.847	EPSD	COSMIC	8.404	Down-regulation
Other_PLK_PLK2_PLK3_ST	P60484	PTEN	Q9H4B4	PLK3	S294	E291K	291	Missense	distal	-3	no	11.776	8.703	EPSD	COSMIC	8.404	Down-regulation
Other_PLK_PLK2_PLK3_ST	P60484	PTEN	Q9H4B4	PLK3	S294	S294N	294	Missense	central	0	yes	11.776	0.000	EPSD	COSMIC	8.404	Loss
Other_PLK_PLK2_PLK3_ST	P60484	PTEN	Q9H4B4	PLK3	S294	C296G	296	Missense	proximal	2	no	11.776	12.171	EPSD	COSMIC	8.404	Up-regulation
Other_PLK_PLK2_PLK3_ST	P60484	PTEN	Q9H4B4	PLK3	S294	E288K	288	Missense	distal	-6	no	11.776	9.370	EPSD	COSMIC	8.404	Down-regulation
Other_PLK_PLK2_PLK3_ST	P60484	PTEN	Q9H4B4	PLK3	S294	S287L	287	Missense	distal	-7	no	11.776	11.370	EPSD	COSMIC	8.404	Down-regulation
Other_PLK_PLK2_PLK3_ST	P60484	PTEN	Q9H4B4	PLK3	S294	K289E	289	Missense	distal	-5	no	11.776	10.536	EPSD	COSMIC	8.404	Down-regulation
Other_PLK_PLK2_PLK3_ST	P60484	PTEN	Q9H4B4	PLK3	S294	E299V	299	Missense	distal	5	no	11.776	12.125	EPSD	COSMIC	8.404	Up-regulation
Other_PLK_PLK2_PLK3_ST	P60484	PTEN	Q9H4B4	PLK3	S294	I300V	300	Missense	distal	6	no	11.776	11.242	EPSD	COSMIC	8.404	Down-regulation
Other_PLK_PLK2_PLK3_ST	P60484	PTEN	Q9H4B4	PLK3	S302	I300V	300	Missense	proximal	-2	no	5.683	9.466	EPSD	COSMIC	8.404	Gain
Other_PLK_PLK2_PLK3_ST	P60484	PTEN	Q9H4B4	PLK3	T321	L325P	325	Missense	distal	4	no	8.272	8.515	EPSD	COSMIC	8.404	Gain
Other_PLK_PLK2_PLK3_ST	P60484	PTEN	Q9H4B4	PLK3	T321	L325H	325	Missense	distal	4	no	8.272	8.506	EPSD	COSMIC	8.404	Gain
Other_PLK_PLK2_PLK3_ST	P60484	PTEN	Q9H4B4	PLK3	T321	V317G	317	Missense	distal	-4	no	8.272	9.046	EPSD	COSMIC	8.404	Gain
Other_PLK_PLK2_PLK3_ST	P60484	PTEN	Q9H4B4	PLK3	T321	E314K	314	Missense	distal	-7	no	8.272	8.725	EPSD	COSMIC	8.404	Gain
Other_PLK_PLK2_PLK3_ST	P60484	PTEN	Q9H4B4	PLK3	T321	N323T	323	Missense	proximal	2	no	8.272	8.966	EPSD	COSMIC	8.404	Gain
Other_PLK_PLK2_PLK3_ST	P60484	PTEN	Q9H4B4	PLK3	T321	N323M	323	Missense	proximal	2	no	8.272	9.128	EPSD	COSMIC	8.404	Gain
Other_PLK_PLK2_PLK3_ST	P60484	PTEN	Q9H4B4	PLK3	T350	V343G	343	Missense	distal	-7	no	8.035	8.458	EPSD	COSMIC	8.404	Gain
Other_PLK_PLK2_PLK3_ST	P60484	PTEN	Q9H4B4	PLK3	S355	P357Q	357	Missense	proximal	2	no	11.481	11.771	EPSD	COSMIC	8.404	Up-regulation
Other_PLK_PLK2_PLK3_ST	P60484	PTEN	Q9H4B4	PLK3	S355	P357L	357	Missense	proximal	2	no	11.481	11.504	EPSD	COSMIC	8.404	Up-regulation
Other_PLK_PLK2_PLK3_ST	P60484	PTEN	Q9H4B4	PLK3	S355	P357S	357	Missense	proximal	2	no	11.481	12.367	EPSD	COSMIC	8.404	Up-regulation
Other_PLK_PLK2_PLK3_ST	P60484	PTEN	Q9H4B4	PLK3	S355	S361N	361	Missense	distal	6	no	11.481	10.855	EPSD	COSMIC	8.404	Down-regulation
Other_PLK_PLK2_PLK3_ST	P60484	PTEN	Q9H4B4	PLK3	S355	T348I	348	Missense	distal	-7	no	11.481	11.754	EPSD	COSMIC	8.404	Up-regulation
Other_PLK_PLK2_PLK3_ST	P60484	PTEN	Q9H4B4	PLK3	S355	S355L	355	Missense	central	0	yes	11.481	0.000	EPSD	COSMIC	8.404	Loss
Other_PLK_PLK2_PLK3_ST	P60484	PTEN	Q9H4B4	PLK3	S355	E358D	358	Missense	distal	3	no	11.481	10.426	EPSD	COSMIC	8.404	Down-regulation
Other_PLK_PLK2_PLK3_ST	P60484	PTEN	Q9H4B4	PLK3	S355	T348R	348	Missense	distal	-7	no	11.481	11.706	EPSD	COSMIC	8.404	Up-regulation
Other_PLK_PLK2_PLK3_ST	P60484	PTEN	Q9H4B4	PLK3	S361	P357Q	357	Missense	distal	-4	no	8.850	8.119	EPSD	COSMIC	8.404	Loss
Other_PLK_PLK2_PLK3_ST	P60484	PTEN	Q9H4B4	PLK3	S361	V365I	365	Missense	distal	4	no	8.850	9.715	EPSD	COSMIC	8.404	Up-regulation
Other_PLK_PLK2_PLK3_ST	P60484	PTEN	Q9H4B4	PLK3	S361	P357L	357	Missense	distal	-4	no	8.850	9.141	EPSD	COSMIC	8.404	Up-regulation
Other_PLK_PLK2_PLK3_ST	P60484	PTEN	Q9H4B4	PLK3	S361	P357S	357	Missense	distal	-4	no	8.850	7.730	EPSD	COSMIC	8.404	Loss
Other_PLK_PLK2_PLK3_ST	P60484	PTEN	Q9H4B4	PLK3	S361	S364C	364	Missense	distal	3	no	8.850	9.090	EPSD	COSMIC	8.404	Up-regulation
Other_PLK_PLK2_PLK3_ST	P60484	PTEN	Q9H4B4	PLK3	S361	S361N	361	Missense	central	0	yes	8.850	0.000	EPSD	COSMIC	8.404	Loss
Other_PLK_PLK2_PLK3_ST	P60484	PTEN	Q9H4B4	PLK3	S361	S355L	355	Missense	distal	-6	no	8.850	6.026	EPSD	COSMIC	8.404	Loss
Other_PLK_PLK2_PLK3_ST	P60484	PTEN	Q9H4B4	PLK3	S361	E358D	358	Missense	distal	-3	no	8.850	7.434	EPSD	COSMIC	8.404	Loss
Other_PLK_PLK2_PLK3_ST	P60484	PTEN	Q9H4B4	PLK3	S362	V369G	369	Missense	distal	7	no	10.455	9.922	EPSD	COSMIC	8.404	Down-regulation
Other_PLK_PLK2_PLK3_ST	P60484	PTEN	Q9H4B4	PLK3	S362	P357Q	357	Missense	distal	-5	no	10.455	9.270	EPSD	COSMIC	8.404	Down-regulation
Other_PLK_PLK2_PLK3_ST	P60484	PTEN	Q9H4B4	PLK3	S362	V365I	365	Missense	distal	3	no	10.455	8.422	EPSD	COSMIC	8.404	Down-regulation
Other_PLK_PLK2_PLK3_ST	P60484	PTEN	Q9H4B4	PLK3	S362	P357L	357	Missense	distal	-5	no	10.455	9.407	EPSD	COSMIC	8.404	Down-regulation
Other_PLK_PLK2_PLK3_ST	P60484	PTEN	Q9H4B4	PLK3	S362	P357S	357	Missense	distal	-5	no	10.455	9.013	EPSD	COSMIC	8.404	Down-regulation
Other_PLK_PLK2_PLK3_ST	P60484	PTEN	Q9H4B4	PLK3	S362	S364C	364	Missense	proximal	2	no	10.455	10.009	EPSD	COSMIC	8.404	Down-regulation
Other_PLK_PLK2_PLK3_ST	P60484	PTEN	Q9H4B4	PLK3	S362	S361N	361	Missense	proximal	-1	no	10.455	10.131	EPSD	COSMIC	8.404	Down-regulation
Other_PLK_PLK2_PLK3_ST	P60484	PTEN	Q9H4B4	PLK3	S362	S355L	355	Missense	distal	-7	no	10.455	10.050	EPSD	COSMIC	8.404	Down-regulation
Other_PLK_PLK2_PLK3_ST	P60484	PTEN	Q9H4B4	PLK3	S362	E358D	358	Missense	distal	-4	no	10.455	12.316	EPSD	COSMIC	8.404	Up-regulation
Other_PLK_PLK2_PLK3_ST	P60484	PTEN	Q9H4B4	PLK3	T366	V369G	369	Missense	distal	3	no	17.213	16.903	PhosphoSitePlus;EPSD	COSMIC	8.404	Down-regulation
Other_PLK_PLK2_PLK3_ST	P60484	PTEN	Q9H4B4	PLK3	T366	V365I	365	Missense	proximal	-1	no	17.213	18.572	PhosphoSitePlus;EPSD	COSMIC	8.404	Up-regulation
Other_PLK_PLK2_PLK3_ST	P60484	PTEN	Q9H4B4	PLK3	T366	S364C	364	Missense	proximal	-2	no	17.213	15.015	PhosphoSitePlus;EPSD	COSMIC	8.404	Down-regulation
Other_PLK_PLK2_PLK3_ST	P60484	PTEN	Q9H4B4	PLK3	T366	S361N	361	Missense	distal	-5	no	17.213	17.040	PhosphoSitePlus;EPSD	COSMIC	8.404	Down-regulation
Other_PLK_PLK2_PLK3_ST	P60484	PTEN	Q9H4B4	PLK3	S370	V369G	369	Missense	proximal	-1	no	17.644	18.573	EPSD;PhosphoSitePlus	COSMIC	8.404	Up-regulation
Other_PLK_PLK2_PLK3_ST	P60484	PTEN	Q9H4B4	PLK3	S370	D375N	375	Missense	distal	5	no	17.644	16.837	EPSD;PhosphoSitePlus	COSMIC	8.404	Down-regulation
Other_PLK_PLK2_PLK3_ST	P60484	PTEN	Q9H4B4	PLK3	S370	V365I	365	Missense	distal	-5	no	17.644	19.018	EPSD;PhosphoSitePlus	COSMIC	8.404	Up-regulation
Other_PLK_PLK2_PLK3_ST	P60484	PTEN	Q9H4B4	PLK3	S370	S364C	364	Missense	distal	-6	no	17.644	16.712	EPSD;PhosphoSitePlus	COSMIC	8.404	Down-regulation
Other_PLK_PLK2_PLK3_ST	P60484	PTEN	Q9H4B4	PLK3	S385	D384G	384	Missense	proximal	-1	no	8.016	8.564	EPSD	COSMIC	8.404	Gain
Other_PLK_PLK2_PLK3_ST	O43852	CALU	Q9H4B4	PLK3	S35	H30P	30	Missense	distal	-5	no	10.177	10.763	EPSD	COSMIC	8.404	Up-regulation
Other_PLK_PLK2_PLK3_ST	O43852	CALU	Q9H4B4	PLK3	S35	P32S	32	Missense	distal	-3	no	10.177	10.484	EPSD	COSMIC	8.404	Up-regulation
Other_PLK_PLK2_PLK3_ST	O43852	CALU	Q9H4B4	PLK3	S35	D41H	41	Missense	distal	6	no	10.177	10.480	EPSD	COSMIC	8.404	Up-regulation
Other_PLK_PLK2_PLK3_ST	O43852	CALU	Q9H4B4	PLK3	S35	K37T	37	Missense	proximal	2	no	10.177	10.921	EPSD	COSMIC	8.404	Up-regulation
Other_PLK_PLK2_PLK3_ST	O43852	CALU	Q9H4B4	PLK3	S44	D46N	46	Missense	proximal	2	no	16.153	14.727	PhosphoSitePlus;EPSD	COSMIC;CCLE	8.404	Down-regulation
Other_PLK_PLK2_PLK3_ST	O43852	CALU	Q9H4B4	PLK3	S44	D41H	41	Missense	distal	-3	no	16.153	14.164	PhosphoSitePlus;EPSD	COSMIC	8.404	Down-regulation
Other_PLK_PLK2_PLK3_ST	O43852	CALU	Q9H4B4	PLK3	S44	K37T	37	Missense	distal	-7	no	16.153	15.851	PhosphoSitePlus;EPSD	COSMIC	8.404	Down-regulation
Other_PLK_PLK2_PLK3_ST	O43852	CALU	Q9H4B4	PLK3	T60	T65I	65	Missense	distal	5	no	17.370	17.901	EPSD;PhosphoSitePlus	COSMIC	8.404	Up-regulation
Other_PLK_PLK2_PLK3_ST	O43852	CALU	Q9H4B4	PLK3	T60	D62Y	62	Missense	proximal	2	no	17.370	15.863	EPSD;PhosphoSitePlus	COSMIC;GDSC;CCLE	8.404	Down-regulation
Other_PLK_PLK2_PLK3_ST	O43852	CALU	Q9H4B4	PLK3	T65	T65I	65	Missense	central	0	yes	10.306	0.000	EPSD	COSMIC	8.404	Loss
Other_PLK_PLK2_PLK3_ST	O43852	CALU	Q9H4B4	PLK3	T65	D62Y	62	Missense	distal	-3	no	10.306	8.202	EPSD	COSMIC;GDSC;CCLE	8.404	Loss
Other_PLK_PLK2_PLK3_ST	O43852	CALU	Q9H4B4	PLK3	T89	G86E	86	Missense	distal	-3	no	8.003	11.998	EPSD	COSMIC	8.404	Gain
Other_PLK_PLK2_PLK3_ST	O43852	CALU	Q9H4B4	PLK3	T89	G86W	86	Missense	distal	-3	no	8.003	10.382	EPSD	COSMIC	8.404	Gain
Other_PLK_PLK2_PLK3_ST	O43852	CALU	Q9H4B4	PLK3	S125	G122D	122	Missense	distal	-3	no	6.329	8.909	EPSD	COSMIC	8.404	Gain
Other_PLK_PLK2_PLK3_ST	O43852	CALU	Q9H4B4	PLK3	T177	A178T	178	Missense	proximal	1	no	17.477	16.279	EPSD;PhosphoSitePlus	COSMIC	8.404	Down-regulation
Other_PLK_PLK2_PLK3_ST	O43852	CALU	Q9H4B4	PLK3	T177	F179L	179	Missense	proximal	2	no	17.477	16.746	EPSD;PhosphoSitePlus	COSMIC	8.404	Down-regulation
Other_PLK_PLK2_PLK3_ST	O43852	CALU	Q9H4B4	PLK3	T177	P182A	182	Missense	distal	5	no	17.477	17.022	EPSD;PhosphoSitePlus	COSMIC	8.404	Down-regulation
Other_PLK_PLK2_PLK3_ST	O43852	CALU	Q9H4B4	PLK3	T196	N203S	203	Missense	distal	7	no	16.416	17.012	EPSD;PhosphoSitePlus	COSMIC	8.404	Up-regulation
Other_PLK_PLK2_PLK3_ST	O43852	CALU	Q9H4B4	PLK3	T196	I200M	200	Missense	distal	4	no	16.416	16.415	EPSD;PhosphoSitePlus	COSMIC	8.404	Down-regulation
Other_PLK_PLK2_PLK3_ST	O43852	CALU	Q9H4B4	PLK3	T196	D190H	190	Missense	distal	-6	no	16.416	15.124	EPSD;PhosphoSitePlus	COSMIC	8.404	Down-regulation
Other_PLK_PLK2_PLK3_ST	O43852	CALU	Q9H4B4	PLK3	T224	P227T	227	Missense	distal	3	no	8.780	9.323	EPSD	COSMIC	8.404	Up-regulation
Other_PLK_PLK2_PLK3_ST	O43852	CALU	Q9H4B4	PLK3	T224	T224I	224	Missense	central	0	yes	8.780	0.000	EPSD	COSMIC	8.404	Loss
Other_PLK_PLK2_PLK3_ST	O43852	CALU	Q9H4B4	PLK3	T254	I258F	258	Missense	distal	4	no	16.980	17.860	EPSD;PhosphoSitePlus	COSMIC	8.404	Up-regulation
Other_PLK_PLK2_PLK3_ST	O43852	CALU	Q9H4B4	PLK3	T254	K251N	251	Missense	distal	-3	no	16.980	14.915	EPSD;PhosphoSitePlus	COSMIC	8.404	Down-regulation
Other_PLK_PLK2_PLK3_ST	O43852	CALU	Q9H4B4	PLK3	T254	P260S	260	Missense	distal	6	no	16.980	16.684	EPSD;PhosphoSitePlus	COSMIC	8.404	Down-regulation
Other_PLK_PLK2_PLK3_ST	O43852	CALU	Q9H4B4	PLK3	T254	D250G	250	Missense	distal	-4	no	16.980	16.272	EPSD;PhosphoSitePlus	COSMIC	8.404	Down-regulation
Other_PLK_PLK2_PLK3_ST	P08238	HSP90AB1	Q9H4B4	PLK3	S45	S45C	45	Missense	central	0	yes	9.492	0.000	EPSD	COSMIC	8.404	Loss
Other_PLK_PLK2_PLK3_ST	P08238	HSP90AB1	Q9H4B4	PLK3	S45	R41L	41	Missense	distal	-4	no	9.492	10.286	EPSD	COSMIC	8.404	Up-regulation
Other_PLK_PLK2_PLK3_ST	P08238	HSP90AB1	Q9H4B4	PLK3	S164	R168H	168	Missense	distal	4	no	8.346	9.412	EPSD	COSMIC	8.404	Gain
Other_PLK_PLK2_PLK3_ST	P08238	HSP90AB1	Q9H4B4	PLK3	S164	R168G	168	Missense	distal	4	no	8.346	8.810	EPSD	COSMIC	8.404	Gain
Other_PLK_PLK2_PLK3_ST	P08238	HSP90AB1	Q9H4B4	PLK3	T297	T297A	297	Missense	central	0	yes	11.067	0.000	EPSD	COSMIC	8.404	Loss
Other_PLK_PLK2_PLK3_ST	P08238	HSP90AB1	Q9H4B4	PLK3	S434	G440E	440	Missense	distal	6	no	12.129	10.869	EPSD	COSMIC	8.404	Down-regulation
Other_PLK_PLK2_PLK3_ST	P08238	HSP90AB1	Q9H4B4	PLK3	T446	R450H	450	Missense	distal	4	no	8.306	9.371	EPSD	COSMIC;GDSC	8.404	Gain
Other_PLK_PLK2_PLK3_ST	P08238	HSP90AB1	Q9H4B4	PLK3	T446	R448L	448	Missense	proximal	2	no	8.306	8.647	EPSD	COSMIC	8.404	Gain
Other_PLK_PLK2_PLK3_ST	P08238	HSP90AB1	Q9H4B4	PLK3	T446	G440E	440	Missense	distal	-6	no	8.306	9.893	EPSD	COSMIC	8.404	Gain
Other_PLK_PLK2_PLK3_ST	P08238	HSP90AB1	Q9H4B4	PLK3	T467	E471Q	471	Missense	distal	4	no	8.268	9.026	EPSD	COSMIC	8.404	Gain
Other_PLK_PLK2_PLK3_ST	P08238	HSP90AB1	Q9H4B4	PLK3	T467	Y472C	472	Missense	distal	5	no	8.268	8.552	EPSD	COSMIC	8.404	Gain
Other_PLK_PLK2_PLK3_ST	P08238	HSP90AB1	Q9H4B4	PLK3	T467	Y472H	472	Missense	distal	5	no	8.268	8.960	EPSD	COSMIC;GDSC;CCLE	8.404	Gain
Other_PLK_PLK2_PLK3_ST	P08238	HSP90AB1	Q9H4B4	PLK3	T467	V473A	473	Missense	distal	6	no	8.268	8.487	EPSD	COSMIC;GDSC;CCLE	8.404	Gain
Other_PLK_PLK2_PLK3_ST	P08238	HSP90AB1	Q9H4B4	PLK3	S468	T467I	467	Missense	proximal	-1	no	11.153	12.458	EPSD	COSMIC	8.404	Up-regulation
Other_PLK_PLK2_PLK3_ST	P08238	HSP90AB1	Q9H4B4	PLK3	S468	E471Q	471	Missense	distal	3	no	11.153	9.827	EPSD	COSMIC	8.404	Down-regulation
Other_PLK_PLK2_PLK3_ST	P08238	HSP90AB1	Q9H4B4	PLK3	S468	Y472C	472	Missense	distal	4	no	11.153	11.323	EPSD	COSMIC	8.404	Up-regulation
Other_PLK_PLK2_PLK3_ST	P08238	HSP90AB1	Q9H4B4	PLK3	S468	Y472H	472	Missense	distal	4	no	11.153	12.051	EPSD	COSMIC;GDSC;CCLE	8.404	Up-regulation
Other_PLK_PLK2_PLK3_ST	P08238	HSP90AB1	Q9H4B4	PLK3	S468	V473A	473	Missense	distal	5	no	11.153	11.348	EPSD	COSMIC;GDSC;CCLE	8.404	Up-regulation
Other_PLK_PLK2_PLK3_ST	P08238	HSP90AB1	Q9H4B4	PLK3	S474	T467I	467	Missense	distal	-7	no	11.232	11.505	EPSD	COSMIC	8.404	Up-regulation
Other_PLK_PLK2_PLK3_ST	P08238	HSP90AB1	Q9H4B4	PLK3	S474	E471Q	471	Missense	distal	-3	no	11.232	8.228	EPSD	COSMIC	8.404	Loss
Other_PLK_PLK2_PLK3_ST	P08238	HSP90AB1	Q9H4B4	PLK3	S474	Y472C	472	Missense	proximal	-2	no	11.232	11.316	EPSD	COSMIC	8.404	Up-regulation
Other_PLK_PLK2_PLK3_ST	P08238	HSP90AB1	Q9H4B4	PLK3	S474	Y472H	472	Missense	proximal	-2	no	11.232	12.180	EPSD	COSMIC;GDSC;CCLE	8.404	Up-regulation
Other_PLK_PLK2_PLK3_ST	P08238	HSP90AB1	Q9H4B4	PLK3	S474	V473A	473	Missense	proximal	-1	no	11.232	11.661	EPSD	COSMIC;GDSC;CCLE	8.404	Up-regulation
Other_PLK_PLK2_PLK3_ST	P08238	HSP90AB1	Q9H4B4	PLK3	S556	E555D	555	Missense	proximal	-1	no	8.238	8.905	EPSD	COSMIC;GDSC;CCLE	8.404	Gain
Other_PLK_PLK2_PLK3_ST	P08238	HSP90AB1	Q9H4B4	PLK3	T579	I580F	580	Missense	proximal	1	no	10.122	10.636	EPSD	COSMIC	8.404	Up-regulation
Other_PLK_PLK2_PLK3_ST	P08238	HSP90AB1	Q9H4B4	PLK3	T579	D572N	572	Missense	distal	-7	no	10.122	10.107	EPSD	COSMIC	8.404	Down-regulation
Other_PLK_PLK2_PLK3_ST	P08238	HSP90AB1	Q9H4B4	PLK3	T616	Q609H	609	Missense	distal	-7	no	9.868	9.827	EPSD	COSMIC	8.404	Down-regulation
Other_PLK_PLK2_PLK3_ST	P08238	HSP90AB1	Q9H4B4	PLK3	T616	A622T	622	Missense	distal	6	no	9.868	9.275	EPSD	COSMIC	8.404	Down-regulation
Other_PLK_PLK2_PLK3_ST	P08238	HSP90AB1	Q9H4B4	PLK3	S718	A717V	717	Missense	proximal	-1	no	9.874	9.445	PhosphoSitePlus	COSMIC;GDSC;CCLE	8.404	Down-regulation
Other_PLK_PLK2_PLK3_ST	P06748	NPM1	Q9H4B4	PLK3	S10	R13S	13	Missense	distal	3	no	8.628	8.296	EPSD	COSMIC	8.404	Loss
Other_PLK_PLK2_PLK3_ST	P06748	NPM1	Q9H4B4	PLK3	S10	P14L	14	Missense	distal	4	no	8.628	8.385	EPSD	COSMIC	8.404	Loss
Other_PLK_PLK2_PLK3_ST	P06748	NPM1	Q9H4B4	PLK3	S222	F228S	228	Missense	distal	6	no	9.608	9.130	EPSD	COSMIC	8.404	Down-regulation
Other_PLK_PLK2_PLK3_ST	P06748	NPM1	Q9H4B4	PLK3	S222	G224R	224	Missense	proximal	2	no	9.608	8.454	EPSD	COSMIC	8.404	Down-regulation
Other_PLK_PLK2_PLK3_ST	P06748	NPM1	Q9H4B4	PLK3	S222	S227F	227	Missense	distal	5	no	9.608	9.827	EPSD	COSMIC	8.404	Up-regulation
Other_PLK_PLK2_PLK3_ST	P06748	NPM1	Q9H4B4	PLK3	T234	F228S	228	Missense	distal	-6	no	7.568	9.885	EPSD	COSMIC	8.404	Gain
Other_PLK_PLK2_PLK3_ST	P06748	NPM1	Q9H4B4	PLK3	S243	D246N	246	Missense	distal	3	no	10.094	8.756	EPSD	COSMIC	8.404	Down-regulation
Other_PLK_PLK2_PLK3_ST	P06748	NPM1	Q9H4B4	PLK3	S243	A249G	249	Missense	distal	6	no	10.094	10.477	EPSD	COSMIC	8.404	Up-regulation
Other_PLK_PLK2_PLK3_ST	P06748	NPM1	Q9H4B4	PLK3	S254	I255V	255	Missense	proximal	1	no	11.211	10.348	EPSD	COSMIC	8.404	Down-regulation
Other_PLK_PLK2_PLK3_ST	P06748	NPM1	Q9H4B4	PLK3	S254	L261F	261	Missense	distal	7	no	11.211	10.210	EPSD	COSMIC	8.404	Down-regulation
Other_PLK_PLK2_PLK3_ST	P06748	NPM1	Q9H4B4	PLK3	S254	S260C	260	Missense	distal	6	no	11.211	11.510	EPSD	COSMIC	8.404	Up-regulation
Other_PLK_PLK2_PLK3_ST	P06748	NPM1	Q9H4B4	PLK3	S254	A249G	249	Missense	distal	-5	no	11.211	11.550	EPSD	COSMIC	8.404	Up-regulation
Other_PLK_PLK2_PLK3_ST	P30307	CDC25C	Q9H4B4	PLK3	S14	P19S	19	Missense	distal	5	no	10.589	10.629	EPSD	COSMIC	8.404	Up-regulation
Other_PLK_PLK2_PLK3_ST	P30307	CDC25C	Q9H4B4	PLK3	S57	L54V	54	Missense	distal	-3	no	10.785	9.739	EPSD	COSMIC	8.404	Down-regulation
Other_PLK_PLK2_PLK3_ST	P30307	CDC25C	Q9H4B4	PLK3	S57	V50A	50	Missense	distal	-7	no	10.785	10.427	EPSD	COSMIC	8.404	Down-regulation
Other_PLK_PLK2_PLK3_ST	P30307	CDC25C	Q9H4B4	PLK3	S57	F53L	53	Missense	distal	-4	no	10.785	9.934	EPSD	COSMIC	8.404	Down-regulation
Other_PLK_PLK2_PLK3_ST	P30307	CDC25C	Q9H4B4	PLK3	T67	R70L	70	Missense	distal	3	no	7.873	9.310	EPSD	COSMIC	8.404	Gain
Other_PLK_PLK2_PLK3_ST	P30307	CDC25C	Q9H4B4	PLK3	S168	S168F	168	Missense	central	0	yes	10.346	0.000	EPSD	COSMIC	8.404	Loss
Other_PLK_PLK2_PLK3_ST	P30307	CDC25C	Q9H4B4	PLK3	S168	S161L	161	Missense	distal	-7	no	10.346	9.941	EPSD	COSMIC	8.404	Down-regulation
Other_PLK_PLK2_PLK3_ST	P30307	CDC25C	Q9H4B4	PLK3	S191	A187E	187	Missense	distal	-4	no	18.165	16.552	EPSD;PhosphoSitePlus	COSMIC	8.404	Down-regulation
Other_PLK_PLK2_PLK3_ST	P30307	CDC25C	Q9H4B4	PLK3	S191	S198F	198	Missense	distal	7	no	18.165	16.815	EPSD;PhosphoSitePlus	COSMIC	8.404	Down-regulation
Other_PLK_PLK2_PLK3_ST	P30307	CDC25C	Q9H4B4	PLK3	S191	E189K	189	Missense	proximal	-2	no	18.165	13.270	EPSD;PhosphoSitePlus	COSMIC	8.404	Down-regulation
Other_PLK_PLK2_PLK3_ST	P30307	CDC25C	Q9H4B4	PLK3	S191	S191L	191	Missense	central	0	yes	18.165	0.000	EPSD;PhosphoSitePlus	COSMIC	8.404	Loss
Other_PLK_PLK2_PLK3_ST	P30307	CDC25C	Q9H4B4	PLK3	S191	E189D	189	Missense	proximal	-2	no	18.165	15.100	EPSD;PhosphoSitePlus	COSMIC	8.404	Down-regulation
Other_PLK_PLK2_PLK3_ST	P30307	CDC25C	Q9H4B4	PLK3	S198	S198F	198	Missense	central	0	yes	14.670	0.000	PhosphoSitePlus;EPSD	COSMIC	8.404	Loss
Other_PLK_PLK2_PLK3_ST	P30307	CDC25C	Q9H4B4	PLK3	S198	S191L	191	Missense	distal	-7	no	14.670	14.265	PhosphoSitePlus;EPSD	COSMIC	8.404	Down-regulation
Other_PLK_PLK2_PLK3_ST	P30307	CDC25C	Q9H4B4	PLK3	S277	D276N	276	Missense	proximal	-1	no	9.436	9.081	EPSD	COSMIC	8.404	Down-regulation
Other_PLK_PLK2_PLK3_ST	P05412	JUN	Q9H4B4	PLK3	T8	N15D	15	Missense	distal	7	no	9.222	9.632	EPSD	COSMIC	8.404	Up-regulation
Other_PLK_PLK2_PLK3_ST	P05412	JUN	Q9H4B4	PLK3	T8	T8I	8	Missense	central	0	yes	9.222	0.000	EPSD	COSMIC	8.404	Loss
Other_PLK_PLK2_PLK3_ST	P05412	JUN	Q9H4B4	PLK3	T8	D12H	12	Missense	distal	4	no	9.222	10.201	EPSD	COSMIC	8.404	Up-regulation
Other_PLK_PLK2_PLK3_ST	P05412	JUN	Q9H4B4	PLK3	S37	M38I	38	Missense	proximal	1	no	10.283	10.818	EPSD	COSMIC	8.404	Up-regulation
Other_PLK_PLK2_PLK3_ST	P05412	JUN	Q9H4B4	PLK3	S37	K32E	32	Missense	distal	-5	no	10.283	9.043	EPSD	COSMIC	8.404	Down-regulation
Other_PLK_PLK2_PLK3_ST	P05412	JUN	Q9H4B4	PLK3	S37	P31L	31	Missense	distal	-6	no	10.283	8.272	EPSD	COSMIC	8.404	Loss
Other_PLK_PLK2_PLK3_ST	P05412	JUN	Q9H4B4	PLK3	S37	S37R	37	Missense	central	0	yes	10.283	0.000	EPSD	COSMIC	8.404	Loss
Other_PLK_PLK2_PLK3_ST	P05412	JUN	Q9H4B4	PLK3	S37	Q36H	36	Missense	proximal	-1	no	10.283	10.879	EPSD	COSMIC	8.404	Up-regulation
Other_PLK_PLK2_PLK3_ST	P05412	JUN	Q9H4B4	PLK3	S37	S37N	37	Missense	central	0	yes	10.283	0.000	EPSD	COSMIC	8.404	Loss
Other_PLK_PLK2_PLK3_ST	P05412	JUN	Q9H4B4	PLK3	S63	K56N	56	Missense	distal	-7	no	17.555	17.318	EPSD;PhosphoSitePlus	COSMIC	8.404	Down-regulation
Other_PLK_PLK2_PLK3_ST	P05412	JUN	Q9H4B4	PLK3	S63	L61F	61	Missense	proximal	-2	no	17.555	16.016	EPSD;PhosphoSitePlus	COSMIC	8.404	Down-regulation
Other_PLK_PLK2_PLK3_ST	P05412	JUN	Q9H4B4	PLK3	S73	R78H	78	Missense	distal	5	no	16.576	17.057	PhosphoSitePlus;EPSD	COSMIC	8.404	Up-regulation
Other_PLK_PLK2_PLK3_ST	P05412	JUN	Q9H4B4	PLK3	T95	P92Q	92	Missense	distal	-3	no	7.629	8.411	EPSD	COSMIC	8.404	Gain
Other_PLK_PLK2_PLK3_ST	P04637	TP53	Q9H4B4	PLK3	S9	E11Q	11	Missense	proximal	2	no	9.149	6.871	EPSD	COSMIC;GDSC;CCLE	8.404	Loss
Other_PLK_PLK2_PLK3_ST	P04637	TP53	Q9H4B4	PLK3	S9	Q16L	16	Missense	distal	7	no	9.149	9.064	EPSD	COSMIC;GDSC;CCLE	8.404	Down-regulation
Other_PLK_PLK2_PLK3_ST	P04637	TP53	Q9H4B4	PLK3	S9	P13S	13	Missense	distal	4	no	9.149	8.357	EPSD	COSMIC	8.404	Loss
Other_PLK_PLK2_PLK3_ST	P04637	TP53	Q9H4B4	PLK3	S9	V10I	10	Missense	proximal	1	no	9.149	10.012	EPSD	COSMIC	8.404	Up-regulation
Other_PLK_PLK2_PLK3_ST	P04637	TP53	Q9H4B4	PLK3	S9	P8L	8	Missense	proximal	-1	no	9.149	9.073	EPSD	COSMIC	8.404	Down-regulation
Other_PLK_PLK2_PLK3_ST	P04637	TP53	Q9H4B4	PLK3	S9	P8S	8	Missense	proximal	-1	no	9.149	8.921	EPSD	COSMIC	8.404	Down-regulation
Other_PLK_PLK2_PLK3_ST	P04637	TP53	Q9H4B4	PLK3	S9	P13L	13	Missense	distal	4	no	9.149	8.905	EPSD	COSMIC	8.404	Down-regulation
Other_PLK_PLK2_PLK3_ST	P04637	TP53	Q9H4B4	PLK3	S9	Q5H	5	Missense	distal	-4	no	9.149	10.179	EPSD	COSMIC	8.404	Up-regulation
Other_PLK_PLK2_PLK3_ST	P04637	TP53	Q9H4B4	PLK3	S9	V10G	10	Missense	proximal	1	no	9.149	9.468	EPSD	COSMIC	8.404	Up-regulation
Other_PLK_PLK2_PLK3_ST	P04637	TP53	Q9H4B4	PLK3	S9	E3G	3	Missense	distal	-6	no	9.149	7.561	EPSD	COSMIC	8.404	Loss
Other_PLK_PLK2_PLK3_ST	P04637	TP53	Q9H4B4	PLK3	S9	D7H	7	Missense	proximal	-2	no	9.149	6.150	EPSD	COSMIC	8.404	Loss
Other_PLK_PLK2_PLK3_ST	P04637	TP53	Q9H4B4	PLK3	S9	S9G	9	Missense	central	0	yes	9.149	0.000	EPSD	COSMIC	8.404	Loss
Other_PLK_PLK2_PLK3_ST	P04637	TP53	Q9H4B4	PLK3	S9	S15I	15	Missense	distal	6	no	9.149	9.342	EPSD	COSMIC	8.404	Up-regulation
Other_PLK_PLK2_PLK3_ST	P04637	TP53	Q9H4B4	PLK3	S9	D7Y	7	Missense	proximal	-2	no	9.149	5.202	EPSD	COSMIC	8.404	Loss
Other_PLK_PLK2_PLK3_ST	P04637	TP53	Q9H4B4	PLK3	S20	S20L	20	Missense	central	0	yes	14.863	0.000	PhosphoSitePlus	COSMIC	8.404	Loss
Other_PLK_PLK2_PLK3_ST	P04637	TP53	Q9H4B4	PLK3	S20	Q16L	16	Missense	distal	-4	no	14.863	15.886	PhosphoSitePlus	COSMIC;GDSC;CCLE	8.404	Up-regulation
Other_PLK_PLK2_PLK3_ST	P04637	TP53	Q9H4B4	PLK3	S20	P13S	13	Missense	distal	-7	no	14.863	14.648	PhosphoSitePlus	COSMIC	8.404	Down-regulation
Other_PLK_PLK2_PLK3_ST	P04637	TP53	Q9H4B4	PLK3	S20	E17K	17	Missense	distal	-3	no	14.863	11.790	PhosphoSitePlus	COSMIC	8.404	Down-regulation
Other_PLK_PLK2_PLK3_ST	P04637	TP53	Q9H4B4	PLK3	S20	P13L	13	Missense	distal	-7	no	14.863	14.243	PhosphoSitePlus	COSMIC	8.404	Down-regulation
Other_PLK_PLK2_PLK3_ST	P04637	TP53	Q9H4B4	PLK3	S20	L26P	26	Missense	distal	6	no	14.863	14.911	PhosphoSitePlus	COSMIC	8.404	Up-regulation
Other_PLK_PLK2_PLK3_ST	P04637	TP53	Q9H4B4	PLK3	S20	T18A	18	Missense	proximal	-2	no	14.863	12.734	PhosphoSitePlus	COSMIC	8.404	Down-regulation
Other_PLK_PLK2_PLK3_ST	P04637	TP53	Q9H4B4	PLK3	S20	F19S	19	Missense	proximal	-1	no	14.863	14.242	PhosphoSitePlus	COSMIC	8.404	Down-regulation
Other_PLK_PLK2_PLK3_ST	P04637	TP53	Q9H4B4	PLK3	S20	E17V	17	Missense	distal	-3	no	14.863	11.440	PhosphoSitePlus	COSMIC	8.404	Down-regulation
Other_PLK_PLK2_PLK3_ST	P04637	TP53	Q9H4B4	PLK3	S20	P27T	27	Missense	distal	7	no	14.863	14.173	PhosphoSitePlus	COSMIC	8.404	Down-regulation
Other_PLK_PLK2_PLK3_ST	P04637	TP53	Q9H4B4	PLK3	S20	T18I	18	Missense	proximal	-2	no	14.863	9.248	PhosphoSitePlus	COSMIC	8.404	Down-regulation
Other_PLK_PLK2_PLK3_ST	P04637	TP53	Q9H4B4	PLK3	S20	T18K	18	Missense	proximal	-2	no	14.863	13.028	PhosphoSitePlus	COSMIC	8.404	Down-regulation
Other_PLK_PLK2_PLK3_ST	P04637	TP53	Q9H4B4	PLK3	S20	T18R	18	Missense	proximal	-2	no	14.863	10.910	PhosphoSitePlus	COSMIC	8.404	Down-regulation
Other_PLK_PLK2_PLK3_ST	P04637	TP53	Q9H4B4	PLK3	S20	S15I	15	Missense	distal	-5	no	14.863	16.030	PhosphoSitePlus	COSMIC	8.404	Up-regulation
Other_PLK_PLK2_PLK3_ST	P04637	TP53	Q9H4B4	PLK3	S46	M40I	40	Missense	distal	-6	no	10.086	7.763	EPSD	COSMIC	8.404	Loss
Other_PLK_PLK2_PLK3_ST	P04637	TP53	Q9H4B4	PLK3	S46	W53C	53	Missense	distal	7	no	10.086	9.016	EPSD	COSMIC	8.404	Down-regulation
Other_PLK_PLK2_PLK3_ST	P04637	TP53	Q9H4B4	PLK3	S46	W53G	53	Missense	distal	7	no	10.086	9.157	EPSD	COSMIC	8.404	Down-regulation
Other_PLK_PLK2_PLK3_ST	P04637	TP53	Q9H4B4	PLK3	S46	S46F	46	Missense	central	0	yes	10.086	0.000	EPSD	COSMIC	8.404	Loss
Other_PLK_PLK2_PLK3_ST	P04637	TP53	Q9H4B4	PLK3	S46	D49Y	49	Missense	distal	3	no	10.086	10.041	EPSD	COSMIC	8.404	Down-regulation
Other_PLK_PLK2_PLK3_ST	P04637	TP53	Q9H4B4	PLK3	S46	P47L	47	Missense	proximal	1	no	10.086	10.175	EPSD	COSMIC	8.404	Up-regulation
Other_PLK_PLK2_PLK3_ST	P04637	TP53	Q9H4B4	PLK3	S46	D49H	49	Missense	distal	3	no	10.086	8.995	EPSD	COSMIC;GDSC;CCLE	8.404	Down-regulation
Other_PLK_PLK2_PLK3_ST	P04637	TP53	Q9H4B4	PLK3	S46	P47S	47	Missense	proximal	1	no	10.086	9.481	EPSD	COSMIC	8.404	Down-regulation
Other_PLK_PLK2_PLK3_ST	P04637	TP53	Q9H4B4	PLK3	S46	D41N	41	Missense	distal	-5	no	10.086	10.858	EPSD	COSMIC	8.404	Up-regulation
Other_PLK_PLK2_PLK3_ST	P04637	TP53	Q9H4B4	PLK3	S46	D48H	48	Missense	proximal	2	no	10.086	8.907	EPSD	COSMIC	8.404	Down-regulation
Other_PLK_PLK2_PLK3_ST	P04637	TP53	Q9H4B4	PLK3	S46	D49N	49	Missense	distal	3	no	10.086	8.747	EPSD	COSMIC	8.404	Down-regulation
Other_PLK_PLK2_PLK3_ST	P04637	TP53	Q9H4B4	PLK3	S46	M44I	44	Missense	proximal	-2	no	10.086	5.155	EPSD	COSMIC	8.404	Loss
Other_PLK_PLK2_PLK3_ST	P04637	TP53	Q9H4B4	PLK3	S46	Q52H	52	Missense	distal	6	no	10.086	10.668	EPSD	COSMIC	8.404	Up-regulation
Other_PLK_PLK2_PLK3_ST	P04637	TP53	Q9H4B4	PLK3	S46	D49V	49	Missense	distal	3	no	10.086	9.818	EPSD	COSMIC	8.404	Down-regulation
Other_PLK_PLK2_PLK3_ST	P04637	TP53	Q9H4B4	PLK3	S46	A39V	39	Missense	distal	-7	no	10.086	10.444	EPSD	COSMIC	8.404	Up-regulation
Other_PLK_PLK2_PLK3_ST	P04637	TP53	Q9H4B4	PLK3	S46	A39S	39	Missense	distal	-7	no	10.086	10.942	EPSD	COSMIC	8.404	Up-regulation
Other_PLK_PLK2_PLK3_ST	P04637	TP53	Q9H4B4	PLK3	S46	D42Y	42	Missense	distal	-4	no	10.086	9.364	EPSD	COSMIC	8.404	Down-regulation
Other_PLK_PLK2_PLK3_ST	P04637	TP53	Q9H4B4	PLK3	S46	M44R	44	Missense	proximal	-2	no	10.086	6.817	EPSD	COSMIC	8.404	Loss
Other_PLK_PLK2_PLK3_ST	P04637	TP53	Q9H4B4	PLK3	S46	S46P	46	Missense	central	0	yes	10.086	0.000	EPSD	COSMIC	8.404	Loss
Other_PLK_PLK2_PLK3_ST	P04637	TP53	Q9H4B4	PLK3	S46	M44V	44	Missense	proximal	-2	no	10.086	8.938	EPSD	COSMIC	8.404	Down-regulation
Other_PLK_PLK2_PLK3_ST	P04637	TP53	Q9H4B4	PLK3	S46	L45P	45	Missense	proximal	-1	no	10.086	10.161	EPSD	COSMIC	8.404	Up-regulation
Other_PLK_PLK2_PLK3_ST	P04637	TP53	Q9H4B4	PLK3	S46	M44T	44	Missense	proximal	-2	no	10.086	10.771	EPSD	COSMIC	8.404	Up-regulation
Other_PLK_PLK2_PLK3_ST	P04637	TP53	Q9H4B4	PLK3	S46	A39T	39	Missense	distal	-7	no	10.086	10.248	EPSD	COSMIC	8.404	Up-regulation
Other_PLK_PLK2_PLK3_ST	P04637	TP53	Q9H4B4	PLK3	S46	L43F	43	Missense	distal	-3	no	10.086	9.277	EPSD	COSMIC	8.404	Down-regulation
Other_PLK_PLK2_PLK3_ST	P04637	TP53	Q9H4B4	PLK3	S46	D41H	41	Missense	distal	-5	no	10.086	11.886	EPSD	COSMIC	8.404	Up-regulation
Other_PLK_PLK2_PLK3_ST	P04637	TP53	Q9H4B4	PLK3	S46	D49E	49	Missense	distal	3	no	10.086	11.141	EPSD	COSMIC	8.404	Up-regulation
Other_PLK_PLK2_PLK3_ST	P04637	TP53	Q9H4B4	PLK3	S46	D49G	49	Missense	distal	3	no	10.086	9.509	EPSD	COSMIC	8.404	Down-regulation
Other_PLK_PLK2_PLK3_ST	P04637	TP53	Q9H4B4	PLK3	S46	D48A	48	Missense	proximal	2	no	10.086	8.201	EPSD	COSMIC	8.404	Loss
Other_PLK_PLK2_PLK3_ST	P04637	TP53	Q9H4B4	PLK3	S46	D48Y	48	Missense	proximal	2	no	10.086	8.579	EPSD	COSMIC	8.404	Down-regulation
Other_PLK_PLK2_PLK3_ST	P04637	TP53	Q9H4B4	PLK3	S46	D48E	48	Missense	proximal	2	no	10.086	10.241	EPSD	COSMIC	8.404	Up-regulation
Other_PLK_PLK2_PLK3_ST	P04637	TP53	Q9H4B4	PLK3	S46	D49I	49	Missense	distal	3	no	10.086	7.785	EPSD	COSMIC	8.404	Loss
Other_PLK_PLK2_PLK3_ST	P04637	TP53	Q9H4B4	PLK3	S46	D41E	41	Missense	distal	-5	no	10.086	10.348	EPSD	COSMIC	8.404	Up-regulation
Other_PLK_PLK2_PLK3_ST	P04637	TP53	Q9H4B4	PLK3	T150	P151N	151	Missense	proximal	1	no	9.520	8.099	EPSD	COSMIC	8.404	Loss
Other_PLK_PLK2_PLK3_ST	P04637	TP53	Q9H4B4	PLK3	T150	P152A	152	Missense	proximal	2	no	9.520	10.047	EPSD	COSMIC	8.404	Up-regulation
Other_PLK_PLK2_PLK3_ST	P04637	TP53	Q9H4B4	PLK3	T150	P152T	152	Missense	proximal	2	no	9.520	11.199	EPSD	COSMIC	8.404	Up-regulation
Other_PLK_PLK2_PLK3_ST	P04637	TP53	Q9H4B4	PLK3	T150	P152H	152	Missense	proximal	2	no	9.520	10.753	EPSD	COSMIC	8.404	Up-regulation
Other_PLK_PLK2_PLK3_ST	P04637	TP53	Q9H4B4	PLK3	T150	P153T	153	Missense	distal	3	no	9.520	10.063	EPSD	COSMIC	8.404	Up-regulation
Other_PLK_PLK2_PLK3_ST	P04637	TP53	Q9H4B4	PLK3	T150	V147I	147	Missense	distal	-3	no	9.520	5.644	EPSD	COSMIC	8.404	Loss
Other_PLK_PLK2_PLK3_ST	P04637	TP53	Q9H4B4	PLK3	T150	P153L	153	Missense	distal	3	no	9.520	10.750	EPSD	COSMIC	8.404	Up-regulation
Other_PLK_PLK2_PLK3_ST	P04637	TP53	Q9H4B4	PLK3	T150	V147D	147	Missense	distal	-3	no	9.520	11.528	EPSD	COSMIC;GDSC;CCLE	8.404	Up-regulation
Other_PLK_PLK2_PLK3_ST	P04637	TP53	Q9H4B4	PLK3	T150	S149P	149	Missense	proximal	-1	no	9.520	9.747	EPSD	COSMIC	8.404	Up-regulation
Other_PLK_PLK2_PLK3_ST	P04637	TP53	Q9H4B4	PLK3	T150	P152K	152	Missense	proximal	2	no	9.520	10.455	EPSD	COSMIC	8.404	Up-regulation
Other_PLK_PLK2_PLK3_ST	P04637	TP53	Q9H4B4	PLK3	T150	P153S	153	Missense	distal	3	no	9.520	8.981	EPSD	COSMIC	8.404	Down-regulation
Other_PLK_PLK2_PLK3_ST	P04637	TP53	Q9H4B4	PLK3	T150	G154C	154	Missense	distal	4	no	9.520	9.394	EPSD	COSMIC	8.404	Down-regulation
Other_PLK_PLK2_PLK3_ST	P04637	TP53	Q9H4B4	PLK3	T150	S149F	149	Missense	proximal	-1	no	9.520	10.142	EPSD	COSMIC	8.404	Up-regulation
Other_PLK_PLK2_PLK3_ST	P04637	TP53	Q9H4B4	PLK3	T150	G154D	154	Missense	distal	4	no	9.520	9.143	EPSD	COSMIC	8.404	Down-regulation
Other_PLK_PLK2_PLK3_ST	P04637	TP53	Q9H4B4	PLK3	T150	V157I	157	Missense	distal	7	no	9.520	8.603	EPSD	COSMIC	8.404	Down-regulation
Other_PLK_PLK2_PLK3_ST	P04637	TP53	Q9H4B4	PLK3	T150	W146R	146	Missense	distal	-4	no	9.520	8.161	EPSD	COSMIC	8.404	Loss
Other_PLK_PLK2_PLK3_ST	P04637	TP53	Q9H4B4	PLK3	T150	Q144R	144	Missense	distal	-6	no	9.520	9.633	EPSD	COSMIC	8.404	Up-regulation
Other_PLK_PLK2_PLK3_ST	P04637	TP53	Q9H4B4	PLK3	T150	D148V	148	Missense	proximal	-2	no	9.520	7.692	EPSD	COSMIC	8.404	Loss
Other_PLK_PLK2_PLK3_ST	P04637	TP53	Q9H4B4	PLK3	T150	S149Y	149	Missense	proximal	-1	no	9.520	9.135	EPSD	COSMIC	8.404	Down-regulation
Other_PLK_PLK2_PLK3_ST	P04637	TP53	Q9H4B4	PLK3	T150	T150I	150	Missense	central	0	yes	9.520	0.000	EPSD	COSMIC	8.404	Loss
Other_PLK_PLK2_PLK3_ST	P04637	TP53	Q9H4B4	PLK3	T150	S149T	149	Missense	proximal	-1	no	9.520	9.224	EPSD	COSMIC	8.404	Down-regulation
Other_PLK_PLK2_PLK3_ST	P04637	TP53	Q9H4B4	PLK3	T150	W146G	146	Missense	distal	-4	no	9.520	7.902	EPSD	COSMIC	8.404	Loss
Other_PLK_PLK2_PLK3_ST	P04637	TP53	Q9H4B4	PLK3	T150	L145M	145	Missense	distal	-5	no	9.520	8.628	EPSD	COSMIC	8.404	Down-regulation
Other_PLK_PLK2_PLK3_ST	P04637	TP53	Q9H4B4	PLK3	T150	V143L	143	Missense	distal	-7	no	9.520	9.613	EPSD	COSMIC	8.404	Up-regulation
Other_PLK_PLK2_PLK3_ST	P04637	TP53	Q9H4B4	PLK3	T150	R156S	156	Missense	distal	6	no	9.520	9.771	EPSD	COSMIC	8.404	Up-regulation
Other_PLK_PLK2_PLK3_ST	P04637	TP53	Q9H4B4	PLK3	T150	D148E	148	Missense	proximal	-2	no	9.520	12.585	EPSD	COSMIC	8.404	Up-regulation
Other_PLK_PLK2_PLK3_ST	P04637	TP53	Q9H4B4	PLK3	T150	V147F	147	Missense	distal	-3	no	9.520	9.757	EPSD	COSMIC	8.404	Up-regulation
Other_PLK_PLK2_PLK3_ST	P04637	TP53	Q9H4B4	PLK3	T150	T155A	155	Missense	distal	5	no	9.520	9.889	EPSD	COSMIC	8.404	Up-regulation
Other_PLK_PLK2_PLK3_ST	P04637	TP53	Q9H4B4	PLK3	T150	V147E	147	Missense	distal	-3	no	9.520	12.944	EPSD	COSMIC	8.404	Up-regulation
Other_PLK_PLK2_PLK3_ST	P04637	TP53	Q9H4B4	PLK3	T150	G154I	154	Missense	distal	4	no	9.520	9.756	EPSD	COSMIC	8.404	Up-regulation
Other_PLK_PLK2_PLK3_ST	P04637	TP53	Q9H4B4	PLK3	T150	D148G	148	Missense	proximal	-2	no	9.520	7.446	EPSD	COSMIC	8.404	Loss
Other_PLK_PLK2_PLK3_ST	P04637	TP53	Q9H4B4	PLK3	T150	Q144K	144	Missense	distal	-6	no	9.520	9.827	EPSD	COSMIC	8.404	Up-regulation
Other_PLK_PLK2_PLK3_ST	P04637	TP53	Q9H4B4	PLK3	T150	V147A	147	Missense	distal	-3	no	9.520	10.127	EPSD	COSMIC	8.404	Up-regulation
Other_PLK_PLK2_PLK3_ST	P04637	TP53	Q9H4B4	PLK3	T150	L145V	145	Missense	distal	-5	no	9.520	8.920	EPSD	COSMIC	8.404	Down-regulation
Other_PLK_PLK2_PLK3_ST	P04637	TP53	Q9H4B4	PLK3	T150	T150K	150	Missense	central	0	yes	9.520	0.000	EPSD	COSMIC	8.404	Loss
Other_PLK_PLK2_PLK3_ST	P04637	TP53	Q9H4B4	PLK3	T150	P153H	153	Missense	distal	3	no	9.520	9.682	EPSD	COSMIC	8.404	Up-regulation
Other_PLK_PLK2_PLK3_ST	P04637	TP53	Q9H4B4	PLK3	T150	V157E	157	Missense	distal	7	no	9.520	10.122	EPSD	COSMIC	8.404	Up-regulation
Other_PLK_PLK2_PLK3_ST	P04637	TP53	Q9H4B4	PLK3	T150	T155S	155	Missense	distal	5	no	9.520	10.385	EPSD	COSMIC;CCLE	8.404	Up-regulation
Other_PLK_PLK2_PLK3_ST	P04637	TP53	Q9H4B4	PLK3	T150	D148H	148	Missense	proximal	-2	no	9.520	6.522	EPSD	COSMIC	8.404	Loss
Other_PLK_PLK2_PLK3_ST	P04637	TP53	Q9H4B4	PLK3	T150	P153A	153	Missense	distal	3	no	9.520	9.947	EPSD	COSMIC	8.404	Up-regulation
Other_PLK_PLK2_PLK3_ST	P04637	TP53	Q9H4B4	PLK3	T150	T150R	150	Missense	central	0	yes	9.520	0.000	EPSD	COSMIC	8.404	Loss
Other_PLK_PLK2_PLK3_ST	P04637	TP53	Q9H4B4	PLK3	T150	T155L	155	Missense	distal	5	no	9.520	10.179	EPSD	COSMIC	8.404	Up-regulation
Other_PLK_PLK2_PLK3_ST	P04637	TP53	Q9H4B4	PLK3	T150	G154A	154	Missense	distal	4	no	9.520	9.720	EPSD	COSMIC	8.404	Up-regulation
Other_PLK_PLK2_PLK3_ST	P04637	TP53	Q9H4B4	PLK3	T150	T150A	150	Missense	central	0	yes	9.520	0.000	EPSD	COSMIC	8.404	Loss
Other_PLK_PLK2_PLK3_ST	P04637	TP53	Q9H4B4	PLK3	T150	W146C	146	Missense	distal	-4	no	9.520	8.049	EPSD	COSMIC	8.404	Loss
Other_PLK_PLK2_PLK3_ST	P04637	TP53	Q9H4B4	PLK3	T150	P153F	153	Missense	distal	3	no	9.520	10.040	EPSD	COSMIC	8.404	Up-regulation
Other_PLK_PLK2_PLK3_ST	P04637	TP53	Q9H4B4	PLK3	T150	D148Y	148	Missense	proximal	-2	no	9.520	5.574	EPSD	COSMIC	8.404	Loss
Other_PLK_PLK2_PLK3_ST	P04637	TP53	Q9H4B4	PLK3	T150	G154R	154	Missense	distal	4	no	9.520	9.056	EPSD	COSMIC	8.404	Down-regulation
Other_PLK_PLK2_PLK3_ST	P04637	TP53	Q9H4B4	PLK3	S183	G187V	187	Missense	distal	4	no	12.054	11.425	EPSD	COSMIC	8.404	Down-regulation
Other_PLK_PLK2_PLK3_ST	P04637	TP53	Q9H4B4	PLK3	S183	G187D	187	Missense	distal	4	no	12.054	11.676	EPSD	COSMIC	8.404	Down-regulation
Other_PLK_PLK2_PLK3_ST	P04637	TP53	Q9H4B4	PLK3	S183	G187A	187	Missense	distal	4	no	12.054	12.254	EPSD	COSMIC	8.404	Up-regulation
Other_PLK_PLK2_PLK3_ST	P04637	TP53	Q9H4B4	PLK3	S183	S183C	183	Missense	central	0	yes	12.054	0.000	EPSD	COSMIC	8.404	Loss
Other_PLK_PLK2_PLK3_ST	P04637	TP53	Q9H4B4	PLK3	S183	S183P	183	Missense	central	0	yes	12.054	0.000	EPSD	COSMIC	8.404	Loss
Other_PLK_PLK2_PLK3_ST	P04637	TP53	Q9H4B4	PLK3	S183	S185G	185	Missense	proximal	2	no	12.054	12.003	EPSD	COSMIC	8.404	Down-regulation
Other_PLK_PLK2_PLK3_ST	P04637	TP53	Q9H4B4	PLK3	S183	P190N	190	Missense	distal	7	no	12.054	11.553	EPSD	COSMIC	8.404	Down-regulation
Other_PLK_PLK2_PLK3_ST	P04637	TP53	Q9H4B4	PLK3	S183	D184N	184	Missense	proximal	1	no	12.054	10.844	EPSD	COSMIC	8.404	Down-regulation
Other_PLK_PLK2_PLK3_ST	P04637	TP53	Q9H4B4	PLK3	S183	S185R	185	Missense	proximal	2	no	12.054	10.849	EPSD	COSMIC	8.404	Down-regulation
Other_PLK_PLK2_PLK3_ST	P04637	TP53	Q9H4B4	PLK3	S183	S183L	183	Missense	central	0	yes	12.054	0.000	EPSD	COSMIC	8.404	Loss
Other_PLK_PLK2_PLK3_ST	P04637	TP53	Q9H4B4	PLK3	S183	R181L	181	Missense	proximal	-2	no	12.054	15.418	EPSD	COSMIC	8.404	Up-regulation
Other_PLK_PLK2_PLK3_ST	P04637	TP53	Q9H4B4	PLK3	S183	H178P	178	Missense	distal	-5	no	12.054	12.640	EPSD	COSMIC	8.404	Up-regulation
Other_PLK_PLK2_PLK3_ST	P04637	TP53	Q9H4B4	PLK3	S183	D186N	186	Missense	distal	3	no	12.054	10.715	EPSD	COSMIC	8.404	Down-regulation
Other_PLK_PLK2_PLK3_ST	P04637	TP53	Q9H4B4	PLK3	S183	A189S	189	Missense	distal	6	no	12.054	12.176	EPSD	COSMIC	8.404	Up-regulation
Other_PLK_PLK2_PLK3_ST	P04637	TP53	Q9H4B4	PLK3	S183	H178L	178	Missense	distal	-5	no	12.054	11.593	EPSD	COSMIC	8.404	Down-regulation
Other_PLK_PLK2_PLK3_ST	P04637	TP53	Q9H4B4	PLK3	S183	D184Y	184	Missense	proximal	1	no	12.054	11.999	EPSD	COSMIC	8.404	Down-regulation
Other_PLK_PLK2_PLK3_ST	P04637	TP53	Q9H4B4	PLK3	S183	L188V	188	Missense	distal	5	no	12.054	11.570	EPSD	COSMIC	8.404	Down-regulation
Other_PLK_PLK2_PLK3_ST	P04637	TP53	Q9H4B4	PLK3	S183	A189V	189	Missense	distal	6	no	12.054	11.835	EPSD	COSMIC	8.404	Down-regulation
Other_PLK_PLK2_PLK3_ST	P04637	TP53	Q9H4B4	PLK3	S183	H178Y	178	Missense	distal	-5	no	12.054	11.026	EPSD	COSMIC	8.404	Down-regulation
Other_PLK_PLK2_PLK3_ST	P04637	TP53	Q9H4B4	PLK3	S183	D186E	186	Missense	distal	3	no	12.054	13.109	EPSD	COSMIC	8.404	Up-regulation
Other_PLK_PLK2_PLK3_ST	P04637	TP53	Q9H4B4	PLK3	S183	C182Y	182	Missense	proximal	-1	no	12.054	11.367	EPSD	COSMIC	8.404	Down-regulation
Other_PLK_PLK2_PLK3_ST	P04637	TP53	Q9H4B4	PLK3	S183	D186H	186	Missense	distal	3	no	12.054	10.963	EPSD	COSMIC	8.404	Down-regulation
Other_PLK_PLK2_PLK3_ST	P04637	TP53	Q9H4B4	PLK3	S183	L188Q	188	Missense	distal	5	no	12.054	11.999	EPSD	COSMIC	8.404	Down-regulation
Other_PLK_PLK2_PLK3_ST	P04637	TP53	Q9H4B4	PLK3	S183	H178N	178	Missense	distal	-5	no	12.054	11.026	EPSD	COSMIC	8.404	Down-regulation
Other_PLK_PLK2_PLK3_ST	P04637	TP53	Q9H4B4	PLK3	S183	G187R	187	Missense	distal	4	no	12.054	11.590	EPSD	COSMIC;GDSC	8.404	Down-regulation
Other_PLK_PLK2_PLK3_ST	P04637	TP53	Q9H4B4	PLK3	S183	C182S	182	Missense	proximal	-1	no	12.054	11.752	EPSD	COSMIC	8.404	Down-regulation
Other_PLK_PLK2_PLK3_ST	P04637	TP53	Q9H4B4	PLK3	S183	P190F	190	Missense	distal	7	no	12.054	10.798	EPSD	COSMIC	8.404	Down-regulation
Other_PLK_PLK2_PLK3_ST	P04637	TP53	Q9H4B4	PLK3	S183	G187C	187	Missense	distal	4	no	12.054	11.928	EPSD	COSMIC	8.404	Down-regulation
Other_PLK_PLK2_PLK3_ST	P04637	TP53	Q9H4B4	PLK3	S183	S185T	185	Missense	proximal	2	no	12.054	12.847	EPSD	COSMIC	8.404	Up-regulation
Other_PLK_PLK2_PLK3_ST	P04637	TP53	Q9H4B4	PLK3	S183	P190H	190	Missense	distal	7	no	12.054	11.389	EPSD	COSMIC	8.404	Down-regulation
Other_PLK_PLK2_PLK3_ST	P04637	TP53	Q9H4B4	PLK3	S183	S185N	185	Missense	proximal	2	no	12.054	12.153	EPSD	COSMIC	8.404	Up-regulation
Other_PLK_PLK2_PLK3_ST	P04637	TP53	Q9H4B4	PLK3	S183	D186G	186	Missense	distal	3	no	12.054	11.477	EPSD	COSMIC	8.404	Down-regulation
Other_PLK_PLK2_PLK3_ST	P04637	TP53	Q9H4B4	PLK3	S183	D186V	186	Missense	distal	3	no	12.054	11.787	EPSD	COSMIC	8.404	Down-regulation
Other_PLK_PLK2_PLK3_ST	P04637	TP53	Q9H4B4	PLK3	S183	P177I	177	Missense	distal	-6	no	12.054	10.684	EPSD	COSMIC	8.404	Down-regulation
Other_PLK_PLK2_PLK3_ST	P04637	TP53	Q9H4B4	PLK3	S183	P190A	190	Missense	distal	7	no	12.054	11.964	EPSD	COSMIC	8.404	Down-regulation
Other_PLK_PLK2_PLK3_ST	P04637	TP53	Q9H4B4	PLK3	S183	S185C	185	Missense	proximal	2	no	12.054	11.608	EPSD	COSMIC	8.404	Down-regulation
Other_PLK_PLK2_PLK3_ST	P04637	TP53	Q9H4B4	PLK3	S183	S185I	185	Missense	proximal	2	no	12.054	11.063	EPSD	COSMIC	8.404	Down-regulation
Other_PLK_PLK2_PLK3_ST	P04637	TP53	Q9H4B4	PLK3	S183	A189P	189	Missense	distal	6	no	12.054	12.472	EPSD	COSMIC	8.404	Up-regulation
Other_PLK_PLK2_PLK3_ST	P04637	TP53	Q9H4B4	PLK3	S183	E180Q	180	Missense	distal	-3	no	12.054	9.050	EPSD	COSMIC	8.404	Down-regulation
Other_PLK_PLK2_PLK3_ST	P04637	TP53	Q9H4B4	PLK3	S183	R181S	181	Missense	proximal	-2	no	12.054	14.339	EPSD	COSMIC	8.404	Up-regulation
Other_PLK_PLK2_PLK3_ST	P04637	TP53	Q9H4B4	PLK3	S183	C182R	182	Missense	proximal	-1	no	12.054	11.566	EPSD	COSMIC	8.404	Down-regulation
Other_PLK_PLK2_PLK3_ST	P04637	TP53	Q9H4B4	PLK3	S183	E180G	180	Missense	distal	-3	no	12.054	8.058	EPSD	COSMIC	8.404	Loss
Other_PLK_PLK2_PLK3_ST	P04637	TP53	Q9H4B4	PLK3	S183	L188M	188	Missense	distal	5	no	12.054	11.965	EPSD	COSMIC	8.404	Down-regulation
Other_PLK_PLK2_PLK3_ST	P04637	TP53	Q9H4B4	PLK3	S183	P177F	177	Missense	distal	-6	no	12.054	10.551	EPSD	COSMIC	8.404	Down-regulation
Other_PLK_PLK2_PLK3_ST	P04637	TP53	Q9H4B4	PLK3	S183	D184E	184	Missense	proximal	1	no	12.054	10.727	EPSD	COSMIC	8.404	Down-regulation
Other_PLK_PLK2_PLK3_ST	P04637	TP53	Q9H4B4	PLK3	S183	A189G	189	Missense	distal	6	no	12.054	12.436	EPSD	COSMIC	8.404	Up-regulation
Other_PLK_PLK2_PLK3_ST	P04637	TP53	Q9H4B4	PLK3	S183	R181G	181	Missense	proximal	-2	no	12.054	13.928	EPSD	COSMIC	8.404	Up-regulation
Other_PLK_PLK2_PLK3_ST	P04637	TP53	Q9H4B4	PLK3	S183	D186X	186	Missense	distal	3	no	12.054	11.213	EPSD	COSMIC	8.404	Down-regulation
Other_PLK_PLK2_PLK3_ST	P04637	TP53	Q9H4B4	PLK3	S183	R181Y	181	Missense	proximal	-2	no	12.054	12.056	EPSD	COSMIC	8.404	Up-regulation
Other_PLK_PLK2_PLK3_ST	P04637	TP53	Q9H4B4	PLK3	S183	D184G	184	Missense	proximal	1	no	12.054	11.856	EPSD	COSMIC	8.404	Down-regulation
Other_PLK_PLK2_PLK3_ST	P04637	TP53	Q9H4B4	PLK3	T304	S303F	303	Missense	proximal	-1	no	7.878	8.499	EPSD	COSMIC	8.404	Gain
Other_PLK_PLK2_PLK3_ST	P04637	TP53	Q9H4B4	PLK3	T304	P301L	301	Missense	distal	-3	no	7.878	9.286	EPSD	COSMIC	8.404	Gain
Other_PLK_PLK2_PLK3_ST	P04637	TP53	Q9H4B4	PLK3	T304	H297P	297	Missense	distal	-7	no	7.878	8.452	EPSD	COSMIC	8.404	Gain
Other_PLK_PLK2_PLK3_ST	P04637	TP53	Q9H4B4	PLK3	T304	G302E	302	Missense	proximal	-2	no	7.878	13.018	EPSD	COSMIC	8.404	Gain
Other_PLK_PLK2_PLK3_ST	P04637	TP53	Q9H4B4	PLK3	T304	N310L	310	Missense	distal	6	no	7.878	8.752	EPSD	COSMIC	8.404	Gain
Other_PLK_PLK2_PLK3_ST	P04637	TP53	Q9H4B4	PLK3	T304	N311Y	311	Missense	distal	7	no	7.878	9.259	EPSD	COSMIC	8.404	Gain
Other_PLK_PLK2_PLK3_ST	P04637	TP53	Q9H4B4	PLK3	T304	L299P	299	Missense	distal	-5	no	7.878	8.926	EPSD	COSMIC	8.404	Gain
Other_PLK_PLK2_PLK3_ST	P04637	TP53	Q9H4B4	PLK3	T304	N310H	310	Missense	distal	6	no	7.878	8.829	EPSD	COSMIC	8.404	Gain
Other_PLK_PLK2_PLK3_ST	P04637	TP53	Q9H4B4	PLK3	T304	R306Q	306	Missense	proximal	2	no	7.878	8.486	EPSD	COSMIC	8.404	Gain
Other_PLK_PLK2_PLK3_ST	P04637	TP53	Q9H4B4	PLK3	T304	N310D	310	Missense	distal	6	no	7.878	8.526	EPSD	COSMIC	8.404	Gain
Other_PLK_PLK2_PLK3_ST	P04637	TP53	Q9H4B4	PLK3	T304	P301A	301	Missense	distal	-3	no	7.878	8.848	EPSD	COSMIC	8.404	Gain
Other_PLK_PLK2_PLK3_ST	P04637	TP53	Q9H4B4	PLK3	T304	P301Q	301	Missense	distal	-3	no	7.878	8.660	EPSD	COSMIC	8.404	Gain
Other_PLK_PLK2_PLK3_ST	P04637	TP53	Q9H4B4	PLK3	S315	N310T	310	Missense	distal	-5	no	11.511	12.329	EPSD	COSMIC	8.404	Up-regulation
Other_PLK_PLK2_PLK3_ST	P04637	TP53	Q9H4B4	PLK3	S315	Q317R	317	Missense	proximal	2	no	11.511	10.902	EPSD	COSMIC	8.404	Down-regulation
Other_PLK_PLK2_PLK3_ST	P04637	TP53	Q9H4B4	PLK3	S315	P309S	309	Missense	distal	-6	no	11.511	12.324	EPSD	COSMIC;GDSC;CCLE	8.404	Up-regulation
Other_PLK_PLK2_PLK3_ST	P04637	TP53	Q9H4B4	PLK3	S315	K319E	319	Missense	distal	4	no	11.511	10.286	EPSD	COSMIC	8.404	Down-regulation
Other_PLK_PLK2_PLK3_ST	P04637	TP53	Q9H4B4	PLK3	S315	P322L	322	Missense	distal	7	no	11.511	11.256	EPSD	COSMIC	8.404	Down-regulation
Other_PLK_PLK2_PLK3_ST	P04637	TP53	Q9H4B4	PLK3	S315	K320N	320	Missense	distal	5	no	11.511	11.067	EPSD	COSMIC;GDSC;CCLE	8.404	Down-regulation
Other_PLK_PLK2_PLK3_ST	P04637	TP53	Q9H4B4	PLK3	S315	N310L	310	Missense	distal	-5	no	11.511	12.077	EPSD	COSMIC	8.404	Up-regulation
Other_PLK_PLK2_PLK3_ST	P04637	TP53	Q9H4B4	PLK3	S315	T312S	312	Missense	distal	-3	no	11.511	10.509	EPSD	COSMIC	8.404	Down-regulation
Other_PLK_PLK2_PLK3_ST	P04637	TP53	Q9H4B4	PLK3	S315	N311Y	311	Missense	distal	-4	no	11.511	13.021	EPSD	COSMIC	8.404	Up-regulation
Other_PLK_PLK2_PLK3_ST	P04637	TP53	Q9H4B4	PLK3	S315	P322R	322	Missense	distal	7	no	11.511	11.118	EPSD	COSMIC	8.404	Down-regulation
Other_PLK_PLK2_PLK3_ST	P04637	TP53	Q9H4B4	PLK3	S315	N311K	311	Missense	distal	-4	no	11.511	12.942	EPSD	COSMIC	8.404	Up-regulation
Other_PLK_PLK2_PLK3_ST	P04637	TP53	Q9H4B4	PLK3	S315	Q317K	317	Missense	proximal	2	no	11.511	12.155	EPSD	COSMIC	8.404	Up-regulation
Other_PLK_PLK2_PLK3_ST	P04637	TP53	Q9H4B4	PLK3	S315	S315P	315	Missense	central	0	yes	11.511	0.000	EPSD	COSMIC	8.404	Loss
Other_PLK_PLK2_PLK3_ST	P04637	TP53	Q9H4B4	PLK3	S315	N310H	310	Missense	distal	-5	no	11.511	12.538	EPSD	COSMIC	8.404	Up-regulation
Other_PLK_PLK2_PLK3_ST	P04637	TP53	Q9H4B4	PLK3	S315	S314C	314	Missense	proximal	-1	no	11.511	11.812	EPSD	COSMIC	8.404	Up-regulation
Other_PLK_PLK2_PLK3_ST	P04637	TP53	Q9H4B4	PLK3	S315	P318A	318	Missense	distal	3	no	11.511	11.938	EPSD	COSMIC	8.404	Up-regulation
Other_PLK_PLK2_PLK3_ST	P04637	TP53	Q9H4B4	PLK3	S315	P316L	316	Missense	proximal	1	no	11.511	11.600	EPSD	COSMIC	8.404	Up-regulation
Other_PLK_PLK2_PLK3_ST	P04637	TP53	Q9H4B4	PLK3	S315	L308M	308	Missense	distal	-7	no	11.511	11.125	EPSD	COSMIC	8.404	Down-regulation
Other_PLK_PLK2_PLK3_ST	P04637	TP53	Q9H4B4	PLK3	S315	S313C	313	Missense	proximal	-2	no	11.511	9.312	EPSD	COSMIC	8.404	Down-regulation
Other_PLK_PLK2_PLK3_ST	P04637	TP53	Q9H4B4	PLK3	S315	N311H	311	Missense	distal	-4	no	11.511	14.095	EPSD	COSMIC	8.404	Up-regulation
Other_PLK_PLK2_PLK3_ST	P04637	TP53	Q9H4B4	PLK3	S315	L308V	308	Missense	distal	-7	no	11.511	11.418	EPSD	COSMIC	8.404	Down-regulation
Other_PLK_PLK2_PLK3_ST	P04637	TP53	Q9H4B4	PLK3	S315	S314F	314	Missense	proximal	-1	no	11.511	12.132	EPSD	COSMIC	8.404	Up-regulation
Other_PLK_PLK2_PLK3_ST	P04637	TP53	Q9H4B4	PLK3	S315	K319R	319	Missense	distal	4	no	11.511	10.998	EPSD	COSMIC	8.404	Down-regulation
Other_PLK_PLK2_PLK3_ST	P04637	TP53	Q9H4B4	PLK3	S315	T312A	312	Missense	distal	-3	no	11.511	11.172	EPSD	COSMIC	8.404	Down-regulation
Other_PLK_PLK2_PLK3_ST	P04637	TP53	Q9H4B4	PLK3	S315	N310D	310	Missense	distal	-5	no	11.511	10.738	EPSD	COSMIC	8.404	Down-regulation
Other_PLK_PLK2_PLK3_ST	P04637	TP53	Q9H4B4	PLK3	S315	N311D	311	Missense	distal	-4	no	11.511	13.743	EPSD	COSMIC	8.404	Up-regulation
Other_PLK_PLK2_PLK3_ST	P04637	TP53	Q9H4B4	PLK3	S315	P309R	309	Missense	distal	-6	no	11.511	10.234	EPSD	COSMIC	8.404	Down-regulation
Other_PLK_PLK2_PLK3_ST	P04637	TP53	Q9H4B4	PLK3	S315	S313N	313	Missense	proximal	-2	no	11.511	10.333	EPSD	COSMIC	8.404	Down-regulation
Other_PLK_PLK2_PLK3_ST	P04637	TP53	Q9H4B4	PLK3	S315	Q317P	317	Missense	proximal	2	no	11.511	11.221	EPSD	COSMIC	8.404	Down-regulation
Other_PLK_PLK2_PLK3_ST	P04637	TP53	Q9H4B4	PLK3	S315	P316S	316	Missense	proximal	1	no	11.511	10.906	EPSD	COSMIC	8.404	Down-regulation
Other_PLK_PLK2_PLK3_ST	P04637	TP53	Q9H4B4	PLK3	S367	G361E	361	Missense	distal	-6	no	8.049	9.636	EPSD	COSMIC	8.404	Gain
Other_PLK_PLK2_PLK3_ST	P04637	TP53	Q9H4B4	PLK3	S367	A364D	364	Missense	distal	-3	no	8.049	9.450	EPSD	COSMIC	8.404	Gain
Other_PLK_PLK2_PLK3_ST	P04637	TP53	Q9H4B4	PLK3	S367	G374S	374	Missense	distal	7	no	8.049	9.067	EPSD	COSMIC	8.404	Gain
Other_PLK_PLK2_PLK3_ST	P04637	TP53	Q9H4B4	PLK3	S367	S371P	371	Missense	distal	4	no	8.049	8.841	EPSD	COSMIC	8.404	Gain
Other_PLK_PLK2_PLK3_ST	P14635	CCNB1	Q9H4B4	PLK3	S116	E113D	113	Missense	distal	-3	no	8.529	7.113	EPSD	COSMIC;GDSC;CCLE	8.404	Loss
Other_PLK_PLK2_PLK3_ST	P14635	CCNB1	Q9H4B4	PLK3	S133	A136V	136	Missense	distal	3	no	15.446	16.004	PhosphoSitePlus	COSMIC	8.404	Up-regulation
Other_PLK_PLK2_PLK3_ST	Q14790	CASP8	Q9H4B4	PLK3	S21	K23E	23	Missense	proximal	2	no	7.111	8.744	EPSD	COSMIC	8.404	Gain
Other_PLK_PLK2_PLK3_ST	Q14790	CASP8	Q9H4B4	PLK3	S26	S21F	21	Missense	distal	-5	no	8.632	8.850	EPSD	COSMIC	8.404	Up-regulation
Other_PLK_PLK2_PLK3_ST	Q14790	CASP8	Q9H4B4	PLK3	S26	K23E	23	Missense	distal	-3	no	8.632	11.705	EPSD	COSMIC	8.404	Up-regulation
Other_PLK_PLK2_PLK3_ST	Q14790	CASP8	Q9H4B4	PLK3	S26	D28Y	28	Missense	proximal	2	no	8.632	7.125	EPSD	COSMIC	8.404	Loss
Other_PLK_PLK2_PLK3_ST	Q14790	CASP8	Q9H4B4	PLK3	S26	Y29H	29	Missense	distal	3	no	8.632	7.586	EPSD	COSMIC	8.404	Loss
Other_PLK_PLK2_PLK3_ST	Q14790	CASP8	Q9H4B4	PLK3	S113	V112M	112	Missense	proximal	-1	no	8.576	8.862	EPSD	COSMIC	8.404	Up-regulation
Other_PLK_PLK2_PLK3_ST	Q14790	CASP8	Q9H4B4	PLK3	S113	S109P	109	Missense	distal	-4	no	8.576	9.696	EPSD	COSMIC	8.404	Up-regulation
Other_PLK_PLK2_PLK3_ST	Q14790	CASP8	Q9H4B4	PLK3	S113	E116K	116	Missense	distal	3	no	8.576	7.463	EPSD	COSMIC	8.404	Loss
Other_PLK_PLK2_PLK3_ST	Q14790	CASP8	Q9H4B4	PLK3	S113	S119Y	119	Missense	distal	6	no	8.576	8.385	EPSD	COSMIC	8.404	Loss
Other_PLK_PLK2_PLK3_ST	Q14790	CASP8	Q9H4B4	PLK3	S113	E110K	110	Missense	distal	-3	no	8.576	5.503	EPSD	COSMIC	8.404	Loss
Other_PLK_PLK2_PLK3_ST	Q14790	CASP8	Q9H4B4	PLK3	S113	I108T	108	Missense	distal	-5	no	8.576	8.055	EPSD	COSMIC	8.404	Loss
Other_PLK_PLK2_PLK3_ST	Q14790	CASP8	Q9H4B4	PLK3	S113	E116V	116	Missense	distal	3	no	8.576	7.253	EPSD	COSMIC	8.404	Loss
Other_PLK_PLK2_PLK3_ST	Q14790	CASP8	Q9H4B4	PLK3	S113	F120L	120	Missense	distal	7	no	8.576	9.577	EPSD	COSMIC	8.404	Up-regulation
Other_PLK_PLK2_PLK3_ST	Q14790	CASP8	Q9H4B4	PLK3	S113	S119F	119	Missense	distal	6	no	8.576	9.054	EPSD	COSMIC	8.404	Up-regulation
Other_PLK_PLK2_PLK3_ST	Q14790	CASP8	Q9H4B4	PLK3	S113	S119P	119	Missense	distal	6	no	8.576	8.872	EPSD	COSMIC	8.404	Up-regulation
Other_PLK_PLK2_PLK3_ST	Q14790	CASP8	Q9H4B4	PLK3	S186	E184Q	184	Missense	proximal	-2	no	11.171	6.414	EPSD	COSMIC	8.404	Loss
Other_PLK_PLK2_PLK3_ST	Q14790	CASP8	Q9H4B4	PLK3	S186	S186N	186	Missense	central	0	yes	11.171	0.000	EPSD	COSMIC	8.404	Loss
Other_PLK_PLK2_PLK3_ST	Q14790	CASP8	Q9H4B4	PLK3	S186	E179D	179	Missense	distal	-7	no	11.171	11.403	EPSD	COSMIC	8.404	Up-regulation
Other_PLK_PLK2_PLK3_ST	Q14790	CASP8	Q9H4B4	PLK3	S186	S188A	188	Missense	proximal	2	no	11.171	10.812	EPSD	COSMIC	8.404	Down-regulation
Other_PLK_PLK2_PLK3_ST	Q14790	CASP8	Q9H4B4	PLK3	S186	E179Q	179	Missense	distal	-7	no	11.171	11.699	EPSD	COSMIC	8.404	Up-regulation
Other_PLK_PLK2_PLK3_ST	Q14790	CASP8	Q9H4B4	PLK3	S188	E184Q	184	Missense	distal	-4	no	9.479	10.662	EPSD	COSMIC	8.404	Up-regulation
Other_PLK_PLK2_PLK3_ST	Q14790	CASP8	Q9H4B4	PLK3	S188	S186N	186	Missense	proximal	-2	no	9.479	8.302	EPSD	COSMIC	8.404	Loss
Other_PLK_PLK2_PLK3_ST	Q14790	CASP8	Q9H4B4	PLK3	S188	S188A	188	Missense	central	0	yes	9.479	0.000	EPSD	COSMIC	8.404	Loss
Other_PLK_PLK2_PLK3_ST	Q14790	CASP8	Q9H4B4	PLK3	S192	S186N	186	Missense	distal	-6	no	12.522	12.224	EPSD	COSMIC	8.404	Down-regulation
Other_PLK_PLK2_PLK3_ST	Q14790	CASP8	Q9H4B4	PLK3	S192	S188A	188	Missense	distal	-4	no	12.522	13.343	EPSD	COSMIC	8.404	Up-regulation
Other_PLK_PLK2_PLK3_ST	Q14790	CASP8	Q9H4B4	PLK3	S209	S211L	211	Missense	proximal	2	no	9.243	8.379	EPSD	COSMIC	8.404	Loss
Other_PLK_PLK2_PLK3_ST	Q14790	CASP8	Q9H4B4	PLK3	S209	C203G	203	Missense	distal	-6	no	9.243	9.098	EPSD	COSMIC	8.404	Down-regulation
Other_PLK_PLK2_PLK3_ST	Q14790	CASP8	Q9H4B4	PLK3	S209	C203Y	203	Missense	distal	-6	no	9.243	9.431	EPSD	COSMIC	8.404	Up-regulation
Other_PLK_PLK2_PLK3_ST	Q14790	CASP8	Q9H4B4	PLK3	S209	V205I	205	Missense	distal	-4	no	9.243	10.567	EPSD	COSMIC	8.404	Up-regulation
Other_PLK_PLK2_PLK3_ST	Q14790	CASP8	Q9H4B4	PLK3	S209	S209L	209	Missense	central	0	yes	9.243	0.000	EPSD	COSMIC	8.404	Loss
Other_PLK_PLK2_PLK3_ST	Q14790	CASP8	Q9H4B4	PLK3	S209	T207I	207	Missense	proximal	-2	no	9.243	3.627	EPSD	COSMIC	8.404	Loss
Other_PLK_PLK2_PLK3_ST	Q14790	CASP8	Q9H4B4	PLK3	S209	S211C	211	Missense	proximal	2	no	9.243	8.796	EPSD	COSMIC	8.404	Down-regulation
Other_PLK_PLK2_PLK3_ST	Q14790	CASP8	Q9H4B4	PLK3	S209	D216G	216	Missense	distal	7	no	9.243	8.411	EPSD	COSMIC	8.404	Down-regulation
Other_PLK_PLK2_PLK3_ST	Q14790	CASP8	Q9H4B4	PLK3	S209	P212L	212	Missense	distal	3	no	9.243	10.473	EPSD	COSMIC	8.404	Up-regulation
Other_PLK_PLK2_PLK3_ST	Q14790	CASP8	Q9H4B4	PLK3	S209	P212T	212	Missense	distal	3	no	9.243	9.786	EPSD	COSMIC	8.404	Up-regulation
Other_PLK_PLK2_PLK3_ST	Q14790	CASP8	Q9H4B4	PLK3	S209	P212A	212	Missense	distal	3	no	9.243	9.670	EPSD	COSMIC	8.404	Up-regulation
Other_PLK_PLK2_PLK3_ST	Q14790	CASP8	Q9H4B4	PLK3	S209	R213S	213	Missense	distal	4	no	9.243	9.525	EPSD	COSMIC	8.404	Up-regulation
Other_PLK_PLK2_PLK3_ST	Q14790	CASP8	Q9H4B4	PLK3	S219	R213S	213	Missense	distal	-6	no	8.318	10.407	EPSD	COSMIC	8.404	Gain
Other_PLK_PLK2_PLK3_ST	Q14790	CASP8	Q9H4B4	PLK3	T273	E275D	275	Missense	proximal	2	no	16.799	16.644	PhosphoSitePlus	COSMIC	8.404	Down-regulation
Other_PLK_PLK2_PLK3_ST	Q14790	CASP8	Q9H4B4	PLK3	T273	E275Q	275	Missense	proximal	2	no	16.799	14.522	PhosphoSitePlus	COSMIC	8.404	Down-regulation
Other_PLK_PLK2_PLK3_ST	Q14790	CASP8	Q9H4B4	PLK3	T273	T273I	273	Missense	central	0	yes	16.799	0.000	PhosphoSitePlus	COSMIC	8.404	Loss
Other_PLK_PLK2_PLK3_ST	Q14790	CASP8	Q9H4B4	PLK3	T273	H278L	278	Missense	distal	5	no	16.799	16.212	PhosphoSitePlus	COSMIC	8.404	Down-regulation
Other_PLK_PLK2_PLK3_ST	Q14790	CASP8	Q9H4B4	PLK3	T273	L277F	277	Missense	distal	4	no	16.799	17.548	PhosphoSitePlus	COSMIC	8.404	Up-regulation
Other_PLK_PLK2_PLK3_ST	Q14790	CASP8	Q9H4B4	PLK3	T273	D266N	266	Missense	distal	-7	no	16.799	16.784	PhosphoSitePlus	COSMIC	8.404	Down-regulation
Other_PLK_PLK2_PLK3_ST	Q14790	CASP8	Q9H4B4	PLK3	T273	E280Q	280	Missense	distal	7	no	16.799	16.417	PhosphoSitePlus	COSMIC	8.404	Down-regulation
Other_PLK_PLK2_PLK3_ST	Q14790	CASP8	Q9H4B4	PLK3	T273	E276K	276	Missense	distal	3	no	16.799	15.686	PhosphoSitePlus	COSMIC	8.404	Down-regulation
Other_PLK_PLK2_PLK3_ST	Q14790	CASP8	Q9H4B4	PLK3	T273	A267T	267	Missense	distal	-6	no	16.799	16.091	PhosphoSitePlus	COSMIC	8.404	Down-regulation
Other_PLK_PLK2_PLK3_ST	Q14790	CASP8	Q9H4B4	PLK3	T273	F274Y	274	Missense	proximal	1	no	16.799	15.884	PhosphoSitePlus	COSMIC	8.404	Down-regulation
Other_PLK_PLK2_PLK3_ST	Q14790	CASP8	Q9H4B4	PLK3	T273	F274L	274	Missense	proximal	1	no	16.799	16.240	PhosphoSitePlus	COSMIC	8.404	Down-regulation
Other_PLK_PLK2_PLK3_ST	Q14790	CASP8	Q9H4B4	PLK3	T273	T272M	272	Missense	proximal	-1	no	16.799	17.030	PhosphoSitePlus	COSMIC	8.404	Up-regulation
Other_PLK_PLK2_PLK3_ST	Q14790	CASP8	Q9H4B4	PLK3	T273	E276V	276	Missense	distal	3	no	16.799	15.476	PhosphoSitePlus	COSMIC	8.404	Down-regulation
Other_PLK_PLK2_PLK3_ST	Q14790	CASP8	Q9H4B4	PLK3	T273	F274C	274	Missense	proximal	1	no	16.799	15.787	PhosphoSitePlus	COSMIC	8.404	Down-regulation
Other_PLK_PLK2_PLK3_ST	Q14790	CASP8	Q9H4B4	PLK3	T273	H278N	278	Missense	distal	5	no	16.799	15.554	PhosphoSitePlus	COSMIC	8.404	Down-regulation
Other_PLK_PLK2_PLK3_ST	Q14790	CASP8	Q9H4B4	PLK3	T273	G268V	268	Missense	distal	-5	no	16.799	16.498	PhosphoSitePlus	COSMIC	8.404	Down-regulation
Other_PLK_PLK2_PLK3_ST	Q14790	CASP8	Q9H4B4	PLK3	T273	G268R	268	Missense	distal	-5	no	16.799	17.063	PhosphoSitePlus	COSMIC	8.404	Up-regulation
Other_PLK_PLK2_PLK3_ST	Q14790	CASP8	Q9H4B4	PLK3	T273	H278Y	278	Missense	distal	5	no	16.799	16.108	PhosphoSitePlus	COSMIC	8.404	Down-regulation
Other_PLK_PLK2_PLK3_ST	Q14790	CASP8	Q9H4B4	PLK3	S305	C309Y	309	Missense	distal	4	no	10.915	10.745	EPSD	COSMIC	8.404	Down-regulation
Other_PLK_PLK2_PLK3_ST	Q14790	CASP8	Q9H4B4	PLK3	S305	D303H	303	Missense	proximal	-2	no	10.915	7.917	EPSD	COSMIC	8.404	Loss
Other_PLK_PLK2_PLK3_ST	Q14790	CASP8	Q9H4B4	PLK3	S305	L301P	301	Missense	distal	-4	no	10.915	10.623	EPSD	COSMIC;CCLE	8.404	Down-regulation
Other_PLK_PLK2_PLK3_ST	Q14790	CASP8	Q9H4B4	PLK3	S305	H304D	304	Missense	proximal	-1	no	10.915	10.625	EPSD	COSMIC	8.404	Down-regulation
Other_PLK_PLK2_PLK3_ST	Q14790	CASP8	Q9H4B4	PLK3	S305	D303G	303	Missense	proximal	-2	no	10.915	8.841	EPSD	COSMIC	8.404	Down-regulation
Other_PLK_PLK2_PLK3_ST	Q14790	CASP8	Q9H4B4	PLK3	S305	C312S	312	Missense	distal	7	no	10.915	12.074	EPSD	COSMIC	8.404	Up-regulation
Other_PLK_PLK2_PLK3_ST	Q14790	CASP8	Q9H4B4	PLK3	S305	N306S	306	Missense	proximal	1	no	10.915	11.731	EPSD	COSMIC	8.404	Up-regulation
Other_PLK_PLK2_PLK3_ST	Q14790	CASP8	Q9H4B4	PLK3	S305	D308Y	308	Missense	distal	3	no	10.915	10.870	EPSD	COSMIC	8.404	Down-regulation
Other_PLK_PLK2_PLK3_ST	Q14790	CASP8	Q9H4B4	PLK3	S305	D303V	303	Missense	proximal	-2	no	10.915	9.087	EPSD	COSMIC	8.404	Down-regulation
Other_PLK_PLK2_PLK3_ST	Q14790	CASP8	Q9H4B4	PLK3	S305	I298V	298	Missense	distal	-7	no	10.915	10.839	EPSD	COSMIC	8.404	Down-regulation
Other_PLK_PLK2_PLK3_ST	Q14790	CASP8	Q9H4B4	PLK3	S305	C312Y	312	Missense	distal	7	no	10.915	12.859	EPSD	COSMIC;CCLE	8.404	Up-regulation
Other_PLK_PLK2_PLK3_ST	Q14790	CASP8	Q9H4B4	PLK3	S305	C312F	312	Missense	distal	7	no	10.915	10.723	EPSD	COSMIC	8.404	Down-regulation
Other_PLK_PLK2_PLK3_ST	Q14790	CASP8	Q9H4B4	PLK3	S305	D308V	308	Missense	distal	3	no	10.915	10.648	EPSD	COSMIC	8.404	Down-regulation
Other_PLK_PLK2_PLK3_ST	Q14790	CASP8	Q9H4B4	PLK3	S305	D303N	303	Missense	proximal	-2	no	10.915	8.073	EPSD	COSMIC	8.404	Loss
Other_PLK_PLK2_PLK3_ST	Q14790	CASP8	Q9H4B4	PLK3	S305	M307T	307	Missense	proximal	2	no	10.915	10.753	EPSD	COSMIC	8.404	Down-regulation
Other_PLK_PLK2_PLK3_ST	Q14790	CASP8	Q9H4B4	PLK3	S305	D308G	308	Missense	distal	3	no	10.915	10.338	EPSD	COSMIC	8.404	Down-regulation
Other_PLK_PLK2_PLK3_ST	Q14790	CASP8	Q9H4B4	PLK3	S375	P379L	379	Missense	distal	4	no	9.500	9.257	EPSD	COSMIC	8.404	Down-regulation
Other_PLK_PLK2_PLK3_ST	Q14790	CASP8	Q9H4B4	PLK3	S375	P379S	379	Missense	distal	4	no	9.500	8.708	EPSD	COSMIC	8.404	Down-regulation
Other_PLK_PLK2_PLK3_ST	Q14790	CASP8	Q9H4B4	PLK3	S375	P379Q	379	Missense	distal	4	no	9.500	8.471	EPSD	COSMIC	8.404	Down-regulation
Other_PLK_PLK2_PLK3_ST	Q14790	CASP8	Q9H4B4	PLK3	S375	P379T	379	Missense	distal	4	no	9.500	8.275	EPSD	COSMIC	8.404	Loss
Other_PLK_PLK2_PLK3_ST	Q14790	CASP8	Q9H4B4	PLK3	S375	S375L	375	Missense	central	0	yes	9.500	0.000	EPSD	COSMIC	8.404	Loss
Other_PLK_PLK2_PLK3_ST	Q14790	CASP8	Q9H4B4	PLK3	S375	E376V	376	Missense	proximal	1	no	9.500	10.309	EPSD	COSMIC	8.404	Up-regulation
Other_PLK_PLK2_PLK3_ST	Q14790	CASP8	Q9H4B4	PLK3	S375	E372D	372	Missense	distal	-3	no	9.500	8.084	EPSD	COSMIC	8.404	Loss
Other_PLK_PLK2_PLK3_ST	P30304	CDC25A	Q9H4B4	PLK3	S239	P244T	244	Missense	distal	5	no	10.258	9.433	EPSD	COSMIC	8.404	Down-regulation
Other_PLK_PLK2_PLK3_ST	P30304	CDC25A	Q9H4B4	PLK3	S239	C236Y	236	Missense	distal	-3	no	10.258	12.366	EPSD	COSMIC	8.404	Up-regulation
Other_PLK_PLK2_PLK3_ST	P30304	CDC25A	Q9H4B4	PLK3	S239	C236S	236	Missense	distal	-3	no	10.258	12.407	EPSD	COSMIC	8.404	Up-regulation
Other_PLK_PLK2_PLK3_ST	P30304	CDC25A	Q9H4B4	PLK3	S266	L264V	264	Missense	proximal	-2	no	8.413	7.170	EPSD	COSMIC	8.404	Loss
Other_PLK_PLK2_PLK3_ST	P30304	CDC25A	Q9H4B4	PLK3	S266	R270Q	270	Missense	distal	4	no	8.413	8.458	EPSD	COSMIC	8.404	Up-regulation
Other_PLK_PLK2_PLK3_ST	P30304	CDC25A	Q9H4B4	PLK3	S317	S320Y	320	Missense	distal	3	no	7.385	9.131	EPSD	COSMIC	8.404	Gain
Other_PLK_PLK2_PLK3_ST	P30304	CDC25A	Q9H4B4	PLK3	S519	L521M	521	Missense	proximal	2	no	9.895	11.714	EPSD	COSMIC	8.404	Up-regulation
Other_PLK_PLK2_PLK3_ST	Q16625	OCLN	Q9H4B4	PLK3	S378	G372D	372	Missense	distal	-6	no	7.874	9.037	EPSD	COSMIC	8.404	Gain
Other_PLK_PLK2_PLK3_ST	Q16143	SNCB	Q9H4B4	PLK3	S118	Y119F	119	Missense	proximal	1	no	12.203	13.117	PhosphoSitePlus	COSMIC	8.404	Up-regulation
Other_PLK_PLK2_PLK3_ST	Q16143	SNCB	Q9H4B4	PLK3	S118	M112K	112	Missense	distal	-6	no	12.203	10.168	PhosphoSitePlus	COSMIC	8.404	Down-regulation
Other_PLK_PLK2_PLK3_ST	Q16143	SNCB	Q9H4B4	PLK3	S118	Y119C	119	Missense	proximal	1	no	12.203	12.105	PhosphoSitePlus	COSMIC	8.404	Down-regulation
Other_PLK_PLK2_PLK3_ST	Q16143	SNCB	Q9H4B4	PLK3	S118	Q124K	124	Missense	distal	6	no	12.203	12.589	PhosphoSitePlus	COSMIC	8.404	Up-regulation
Other_PLK_PLK2_PLK3_ST	Q16143	SNCB	Q9H4B4	PLK3	S118	E117A	117	Missense	proximal	-1	no	12.203	12.918	PhosphoSitePlus	COSMIC	8.404	Up-regulation
Other_PLK_PLK2_PLK3_ST	Q16665	HIF1A	Q9H4B4	PLK3	S58	L54I	54	Missense	distal	-4	no	11.014	10.512	EPSD	COSMIC	8.404	Down-regulation
Other_PLK_PLK2_PLK3_ST	Q16665	HIF1A	Q9H4B4	PLK3	S58	S58Y	58	Missense	central	0	yes	11.014	0.000	EPSD	COSMIC	8.404	Loss
Other_PLK_PLK2_PLK3_ST	Q16665	HIF1A	Q9H4B4	PLK3	S58	I64M	64	Missense	distal	6	no	11.014	10.697	EPSD	COSMIC	8.404	Down-regulation
Other_PLK_PLK2_PLK3_ST	Q16665	HIF1A	Q9H4B4	PLK3	S58	S52L	52	Missense	distal	-6	no	11.014	8.190	EPSD	COSMIC	8.404	Loss
Other_PLK_PLK2_PLK3_ST	Q16665	HIF1A	Q9H4B4	PLK3	T63	S58Y	58	Missense	distal	-5	no	9.042	8.868	EPSD	COSMIC	8.404	Down-regulation
Other_PLK_PLK2_PLK3_ST	Q16665	HIF1A	Q9H4B4	PLK3	T63	R68P	68	Missense	distal	5	no	9.042	9.102	EPSD	COSMIC	8.404	Up-regulation
Other_PLK_PLK2_PLK3_ST	Q16665	HIF1A	Q9H4B4	PLK3	T63	I64M	64	Missense	proximal	1	no	9.042	8.507	EPSD	COSMIC	8.404	Down-regulation
Other_PLK_PLK2_PLK3_ST	Q16665	HIF1A	Q9H4B4	PLK3	T63	Y66C	66	Missense	distal	3	no	9.042	7.536	EPSD	COSMIC	8.404	Loss
Other_PLK_PLK2_PLK3_ST	Q16665	HIF1A	Q9H4B4	PLK3	T149	T149R	149	Missense	central	0	yes	9.051	0.000	EPSD	COSMIC	8.404	Loss
Other_PLK_PLK2_PLK3_ST	Q16665	HIF1A	Q9H4B4	PLK3	T149	V155M	155	Missense	distal	6	no	9.051	9.268	EPSD	COSMIC	8.404	Up-regulation
Other_PLK_PLK2_PLK3_ST	Q16665	HIF1A	Q9H4B4	PLK3	T290	H292R	292	Missense	proximal	2	no	11.599	10.047	EPSD	COSMIC	8.404	Down-regulation
Other_PLK_PLK2_PLK3_ST	Q16665	HIF1A	Q9H4B4	PLK3	T290	D283H	283	Missense	distal	-7	no	11.599	11.854	EPSD	COSMIC;GDSC;CCLE	8.404	Up-regulation
Other_PLK_PLK2_PLK3_ST	Q16665	HIF1A	Q9H4B4	PLK3	T290	T290A	290	Missense	central	0	yes	11.599	0.000	EPSD	COSMIC	8.404	Loss
Other_PLK_PLK2_PLK3_ST	Q16665	HIF1A	Q9H4B4	PLK3	T296	H292R	292	Missense	distal	-4	no	10.927	10.126	EPSD	COSMIC	8.404	Down-regulation
Other_PLK_PLK2_PLK3_ST	Q16665	HIF1A	Q9H4B4	PLK3	T296	T290A	290	Missense	distal	-6	no	10.927	11.635	EPSD	COSMIC	8.404	Up-regulation
Other_PLK_PLK2_PLK3_ST	Q16665	HIF1A	Q9H4B4	PLK3	T455	P452A	452	Missense	distal	-3	no	10.106	11.076	EPSD	COSMIC	8.404	Up-regulation
Other_PLK_PLK2_PLK3_ST	Q16665	HIF1A	Q9H4B4	PLK3	T455	A456T	456	Missense	proximal	1	no	10.106	8.908	EPSD	COSMIC	8.404	Down-regulation
Other_PLK_PLK2_PLK3_ST	Q16665	HIF1A	Q9H4B4	PLK3	T455	A456S	456	Missense	proximal	1	no	10.106	9.625	EPSD	COSMIC	8.404	Down-regulation
Other_PLK_PLK2_PLK3_ST	Q16665	HIF1A	Q9H4B4	PLK3	S488	T490A	490	Missense	proximal	2	no	11.796	10.644	EPSD	COSMIC	8.404	Down-regulation
Other_PLK_PLK2_PLK3_ST	Q16665	HIF1A	Q9H4B4	PLK3	S488	Q495K	495	Missense	distal	7	no	11.796	11.676	EPSD	COSMIC	8.404	Down-regulation
Other_PLK_PLK2_PLK3_ST	Q16665	HIF1A	Q9H4B4	PLK3	S488	Q495R	495	Missense	distal	7	no	11.796	11.575	EPSD	COSMIC	8.404	Down-regulation
Other_PLK_PLK2_PLK3_ST	Q16665	HIF1A	Q9H4B4	PLK3	S500	Q497H	497	Missense	distal	-3	no	10.251	9.850	EPSD	COSMIC	8.404	Down-regulation
Other_PLK_PLK2_PLK3_ST	Q16665	HIF1A	Q9H4B4	PLK3	S500	R507K	507	Missense	distal	7	no	10.251	10.352	EPSD	COSMIC	8.404	Up-regulation
Other_PLK_PLK2_PLK3_ST	Q16665	HIF1A	Q9H4B4	PLK3	S500	P501L	501	Missense	proximal	1	no	10.251	10.340	EPSD	COSMIC	8.404	Up-regulation
Other_PLK_PLK2_PLK3_ST	Q16665	HIF1A	Q9H4B4	PLK3	S500	Q495K	495	Missense	distal	-5	no	10.251	10.552	EPSD	COSMIC	8.404	Up-regulation
Other_PLK_PLK2_PLK3_ST	Q16665	HIF1A	Q9H4B4	PLK3	S500	Q495R	495	Missense	distal	-5	no	10.251	10.353	EPSD	COSMIC	8.404	Up-regulation
Other_PLK_PLK2_PLK3_ST	Q16665	HIF1A	Q9H4B4	PLK3	S500	D503N	503	Missense	distal	3	no	10.251	8.913	EPSD	COSMIC	8.404	Down-regulation
Other_PLK_PLK2_PLK3_ST	Q16665	HIF1A	Q9H4B4	PLK3	S510	R507K	507	Missense	distal	-3	no	8.689	9.843	EPSD	COSMIC	8.404	Up-regulation
Other_PLK_PLK2_PLK3_ST	Q16665	HIF1A	Q9H4B4	PLK3	S510	E512V	512	Missense	proximal	2	no	8.689	6.787	EPSD	COSMIC;GDSC	8.404	Loss
Other_PLK_PLK2_PLK3_ST	Q16665	HIF1A	Q9H4B4	PLK3	S510	P516H	516	Missense	distal	6	no	8.689	8.719	EPSD	COSMIC	8.404	Up-regulation
Other_PLK_PLK2_PLK3_ST	Q16665	HIF1A	Q9H4B4	PLK3	S510	S517T	517	Missense	distal	7	no	8.689	7.904	EPSD	COSMIC	8.404	Loss
Other_PLK_PLK2_PLK3_ST	Q16665	HIF1A	Q9H4B4	PLK3	S510	D503N	503	Missense	distal	-7	no	8.689	8.673	EPSD	COSMIC	8.404	Down-regulation
Other_PLK_PLK2_PLK3_ST	Q16665	HIF1A	Q9H4B4	PLK3	S515	E512V	512	Missense	distal	-3	no	11.169	7.745	EPSD	COSMIC;GDSC	8.404	Loss
Other_PLK_PLK2_PLK3_ST	Q16665	HIF1A	Q9H4B4	PLK3	S515	P516H	516	Missense	proximal	1	no	11.169	11.055	EPSD	COSMIC	8.404	Down-regulation
Other_PLK_PLK2_PLK3_ST	Q16665	HIF1A	Q9H4B4	PLK3	S515	S517T	517	Missense	proximal	2	no	11.169	11.962	EPSD	COSMIC	8.404	Up-regulation
Other_PLK_PLK2_PLK3_ST	Q16665	HIF1A	Q9H4B4	PLK3	S515	Y522H	522	Missense	distal	7	no	11.169	9.624	EPSD	COSMIC	8.404	Down-regulation
Other_PLK_PLK2_PLK3_ST	Q16665	HIF1A	Q9H4B4	PLK3	S525	M527V	527	Missense	proximal	2	no	9.569	8.393	EPSD	COSMIC	8.404	Loss
Other_PLK_PLK2_PLK3_ST	Q16665	HIF1A	Q9H4B4	PLK3	S525	D524G	524	Missense	proximal	-1	no	9.569	10.117	EPSD	COSMIC	8.404	Up-regulation
Other_PLK_PLK2_PLK3_ST	Q16665	HIF1A	Q9H4B4	PLK3	S525	Y522H	522	Missense	distal	-3	no	9.569	9.684	EPSD	COSMIC	8.404	Up-regulation
Other_PLK_PLK2_PLK3_ST	Q16665	HIF1A	Q9H4B4	PLK3	S576	D570G	570	Missense	distal	-6	no	16.574	15.412	PhosphoSitePlus;EPSD	COSMIC	8.404	Down-regulation
Other_PLK_PLK2_PLK3_ST	Q16665	HIF1A	Q9H4B4	PLK3	S576	P582S	582	Missense	distal	6	no	16.574	16.279	PhosphoSitePlus;EPSD	COSMIC	8.404	Down-regulation
Other_PLK_PLK2_PLK3_ST	Q16665	HIF1A	Q9H4B4	PLK3	S576	D569G	569	Missense	distal	-7	no	16.574	17.113	PhosphoSitePlus;EPSD	COSMIC	8.404	Up-regulation
Other_PLK_PLK2_PLK3_ST	Q16665	HIF1A	Q9H4B4	PLK3	S576	D578N	578	Missense	proximal	2	no	16.574	15.148	PhosphoSitePlus;EPSD	COSMIC	8.404	Down-regulation
Other_PLK_PLK2_PLK3_ST	Q16665	HIF1A	Q9H4B4	PLK3	S576	D571H	571	Missense	distal	-5	no	16.574	18.374	PhosphoSitePlus;EPSD	COSMIC	8.404	Up-regulation
Other_PLK_PLK2_PLK3_ST	Q16665	HIF1A	Q9H4B4	PLK3	S643	A640P	640	Missense	distal	-3	no	9.370	8.400	EPSD	COSMIC;GDSC	8.404	Loss
Other_PLK_PLK2_PLK3_ST	Q16665	HIF1A	Q9H4B4	PLK3	S643	P642S	642	Missense	proximal	-1	no	9.370	9.143	EPSD	COSMIC	8.404	Down-regulation
Other_PLK_PLK2_PLK3_ST	Q16665	HIF1A	Q9H4B4	PLK3	S643	K636N	636	Missense	distal	-7	no	9.370	9.133	EPSD	COSMIC	8.404	Down-regulation
Other_PLK_PLK2_PLK3_ST	Q16665	HIF1A	Q9H4B4	PLK3	S687	P685Q	685	Missense	proximal	-2	no	7.428	8.485	EPSD	COSMIC	8.404	Gain
Other_PLK_PLK2_PLK3_ST	P37840	SNCA	Q9H4B4	PLK3	S129	A124S	124	Missense	distal	-5	no	13.118	13.362	PhosphoSitePlus	COSMIC	8.404	Up-regulation
Other_PLK_PLK2_PLK3_ST	P37840	SNCA	Q9H4B4	PLK3	S129	E130V	130	Missense	proximal	1	no	13.118	13.927	PhosphoSitePlus	COSMIC	8.404	Up-regulation
Other_PLK_PLK2_PLK3_ST	P37840	SNCA	Q9H4B4	PLK3	S129	D135E	135	Missense	distal	6	no	13.118	12.096	PhosphoSitePlus	COSMIC;GDSC;CCLE	8.404	Down-regulation
Other_PLK_PLK2_PLK3_ST	P37840	SNCA	Q9H4B4	PLK3	S129	E130A	130	Missense	proximal	1	no	13.118	14.532	PhosphoSitePlus	COSMIC	8.404	Up-regulation
Other_PLK_PLK2_PLK3_ST	P37840	SNCA	Q9H4B4	PLK3	S129	E123K	123	Missense	distal	-6	no	13.118	10.712	PhosphoSitePlus	COSMIC	8.404	Down-regulation
CMGC_MAPK_JNK_MAPK10_ST	P01106	MYC	P53779	MAPK10	T8	N9H	9	Missense	proximal	1	no	-0.001	0.000	EPSD	COSMIC	0.000	Gain
CMGC_MAPK_JNK_MAPK10_ST	P01106	MYC	P53779	MAPK10	T8	S6D	6	Missense	proximal	-2	no	-0.001	0.000	EPSD	COSMIC	0.000	Gain
CMGC_MAPK_JNK_MAPK10_ST	P01106	MYC	P53779	MAPK10	T58	P59L	59	Missense	proximal	1	no	0.023	-0.003	EPSD;PhosphoSitePlus	COSMIC;CCLE	0.000	Loss
CMGC_MAPK_JNK_MAPK10_ST	P01106	MYC	P53779	MAPK10	T58	T58N	58	Missense	central	0	yes	0.023	0.000	EPSD;PhosphoSitePlus	COSMIC;CCLE	0.000	Loss
CMGC_MAPK_JNK_MAPK10_ST	P01106	MYC	P53779	MAPK10	T58	T58A	58	Missense	central	0	yes	0.023	0.000	EPSD;PhosphoSitePlus	COSMIC;CCLE	0.000	Loss
CMGC_MAPK_JNK_MAPK10_ST	P01106	MYC	P53779	MAPK10	T58	P59A	59	Missense	proximal	1	no	0.023	-0.002	EPSD;PhosphoSitePlus	COSMIC;CCLE	0.000	Loss
CMGC_MAPK_JNK_MAPK10_ST	P01106	MYC	P53779	MAPK10	T58	P59R	59	Missense	proximal	1	no	0.023	-0.002	EPSD;PhosphoSitePlus	COSMIC	0.000	Loss
CMGC_MAPK_JNK_MAPK10_ST	P01106	MYC	P53779	MAPK10	T58	P59S	59	Missense	proximal	1	no	0.023	-0.003	EPSD;PhosphoSitePlus	COSMIC;CCLE	0.000	Loss
CMGC_MAPK_JNK_MAPK10_ST	P01106	MYC	P53779	MAPK10	T58	T58I	58	Missense	central	0	yes	0.023	0.000	EPSD;PhosphoSitePlus	COSMIC;CCLE	0.000	Loss
CMGC_MAPK_JNK_MAPK10_ST	P01106	MYC	P53779	MAPK10	T58	T58P	58	Missense	central	0	yes	0.023	0.000	EPSD;PhosphoSitePlus	COSMIC	0.000	Loss
CMGC_MAPK_JNK_MAPK10_ST	P01106	MYC	P53779	MAPK10	T58	P59Q	59	Missense	proximal	1	no	0.023	-0.002	EPSD;PhosphoSitePlus	COSMIC;CCLE	0.000	Loss
CMGC_MAPK_JNK_MAPK10_ST	P01106	MYC	P53779	MAPK10	T58	P59T	59	Missense	proximal	1	no	0.023	-0.002	EPSD;PhosphoSitePlus	COSMIC	0.000	Loss
CMGC_MAPK_JNK_MAPK10_ST	P01106	MYC	P53779	MAPK10	S62	S62P	62	Missense	central	0	yes	0.023	0.000	EPSD;PhosphoSitePlus	COSMIC;CCLE	0.000	Loss
CMGC_MAPK_JNK_MAPK10_ST	P01106	MYC	P53779	MAPK10	S62	P63L	63	Missense	proximal	1	no	0.023	-0.003	EPSD;PhosphoSitePlus	COSMIC	0.000	Loss
CMGC_MAPK_JNK_MAPK10_ST	P01106	MYC	P53779	MAPK10	S62	P63H	63	Missense	proximal	1	no	0.023	-0.001	EPSD;PhosphoSitePlus	COSMIC	0.000	Loss
CMGC_MAPK_JNK_MAPK10_ST	P01106	MYC	P53779	MAPK10	S62	S62F	62	Missense	central	0	yes	0.023	0.000	EPSD;PhosphoSitePlus	COSMIC	0.000	Loss
CMGC_MAPK_JNK_MAPK10_ST	P01106	MYC	P53779	MAPK10	S62	P63S	63	Missense	proximal	1	no	0.023	-0.003	EPSD;PhosphoSitePlus	COSMIC;CCLE	0.000	Loss
CMGC_MAPK_JNK_MAPK10_ST	P01106	MYC	P53779	MAPK10	S62	P63A	63	Missense	proximal	1	no	0.023	-0.002	EPSD;PhosphoSitePlus	COSMIC	0.000	Loss
CMGC_MAPK_JNK_MAPK10_ST	P01106	MYC	P53779	MAPK10	S62	P63R	63	Missense	proximal	1	no	0.023	-0.001	EPSD;PhosphoSitePlus	COSMIC	0.000	Loss
CMGC_MAPK_JNK_MAPK10_ST	P01106	MYC	P53779	MAPK10	S62	P63T	63	Missense	proximal	1	no	0.023	-0.002	EPSD;PhosphoSitePlus	COSMIC	0.000	Loss
CMGC_MAPK_JNK_MAPK10_ST	P01106	MYC	P53779	MAPK10	S62	S62A	62	Missense	central	0	yes	0.023	0.000	EPSD;PhosphoSitePlus	COSMIC	0.000	Loss
CMGC_MAPK_JNK_MAPK10_ST	P01106	MYC	P53779	MAPK10	S64	R65C	65	Missense	proximal	1	no	-0.001	0.000	EPSD	COSMIC	0.000	Gain
CMGC_MAPK_JNK_MAPK10_ST	P01106	MYC	P53779	MAPK10	S71	S71L	71	Missense	central	0	yes	0.024	0.000	PhosphoSitePlus;EPSD	COSMIC	0.000	Loss
CMGC_MAPK_JNK_MAPK10_ST	P01106	MYC	P53779	MAPK10	S71	S71W	71	Missense	central	0	yes	0.024	0.000	PhosphoSitePlus;EPSD	COSMIC	0.000	Loss
CMGC_MAPK_JNK_MAPK10_ST	P01106	MYC	P53779	MAPK10	S71	S73P	73	Missense	proximal	2	no	0.024	0.023	PhosphoSitePlus;EPSD	COSMIC	0.000	Down-regulation
CMGC_MAPK_JNK_MAPK10_ST	P01106	MYC	P53779	MAPK10	S71	P72F	72	Missense	proximal	1	no	0.024	0.000	PhosphoSitePlus;EPSD	COSMIC	0.000	Down-regulation
CMGC_MAPK_JNK_MAPK10_ST	P01106	MYC	P53779	MAPK10	S71	P72R	72	Missense	proximal	1	no	0.024	-0.001	PhosphoSitePlus;EPSD	COSMIC	0.000	Loss
CMGC_MAPK_JNK_MAPK10_ST	P01106	MYC	P53779	MAPK10	S73	Y74N	74	Missense	proximal	1	no	0.001	-0.001	EPSD	COSMIC;CCLE	0.000	Loss
CMGC_MAPK_JNK_MAPK10_ST	P01106	MYC	P53779	MAPK10	S73	Y74H	74	Missense	proximal	1	no	0.001	0.000	EPSD	COSMIC	0.000	Down-regulation
CMGC_MAPK_JNK_MAPK10_ST	P01106	MYC	P53779	MAPK10	S73	S73P	73	Missense	central	0	yes	0.001	0.000	EPSD	COSMIC	0.000	Loss
CMGC_MAPK_JNK_MAPK10_ST	P01106	MYC	P53779	MAPK10	T78	P79S	79	Missense	proximal	1	no	0.023	-0.003	EPSD	COSMIC	0.000	Loss
CMGC_MAPK_JNK_MAPK10_ST	P01106	MYC	P53779	MAPK10	S81	L82H	82	Missense	proximal	1	no	-0.002	0.000	EPSD	COSMIC	0.000	Gain
CMGC_MAPK_JNK_MAPK10_ST	P01106	MYC	P53779	MAPK10	S151	Y152N	152	Missense	proximal	1	no	0.000	-0.001	EPSD	COSMIC	0.000	Loss
CMGC_MAPK_JNK_MAPK10_ST	P01106	MYC	P53779	MAPK10	S159	G160D	160	Missense	proximal	1	no	-0.002	0.000	EPSD	COSMIC	0.000	Gain
CMGC_MAPK_JNK_MAPK10_ST	P01106	MYC	P53779	MAPK10	S161	P162R	162	Missense	proximal	1	no	0.023	-0.001	EPSD	COSMIC	0.000	Loss
CMGC_MAPK_JNK_MAPK10_ST	P01106	MYC	P53779	MAPK10	S161	S161N	161	Missense	central	0	yes	0.023	0.000	EPSD	COSMIC	0.000	Loss
CMGC_MAPK_JNK_MAPK10_ST	P01106	MYC	P53779	MAPK10	T173	S174Y	174	Missense	proximal	1	no	-0.003	0.001	EPSD	COSMIC	0.000	Gain
CMGC_MAPK_JNK_MAPK10_ST	P01106	MYC	P53779	MAPK10	S175	L176F	176	Missense	proximal	1	no	-0.002	0.000	EPSD	COSMIC	0.000	Gain
CMGC_MAPK_JNK_MAPK10_ST	P01106	MYC	P53779	MAPK10	S175	L176M	176	Missense	proximal	1	no	-0.002	0.000	EPSD	COSMIC	0.000	Gain
CMGC_MAPK_JNK_MAPK10_ST	P01106	MYC	P53779	MAPK10	S204	S203R	203	Missense	proximal	-1	no	0.024	0.023	EPSD	COSMIC	0.000	Down-regulation
CMGC_MAPK_JNK_MAPK10_ST	P01106	MYC	P53779	MAPK10	S204	S203N	203	Missense	proximal	-1	no	0.024	0.023	EPSD	COSMIC;CCLE	0.000	Down-regulation
CMGC_MAPK_JNK_MAPK10_ST	P01106	MYC	P53779	MAPK10	S204	S203I	203	Missense	proximal	-1	no	0.024	0.023	EPSD	COSMIC	0.000	Down-regulation
CMGC_MAPK_JNK_MAPK10_ST	P01106	MYC	P53779	MAPK10	S204	P205S	205	Missense	proximal	1	no	0.024	-0.003	EPSD	COSMIC	0.000	Loss
CMGC_MAPK_JNK_MAPK10_ST	P01106	MYC	P53779	MAPK10	S204	S204A	204	Missense	central	0	yes	0.024	0.000	EPSD	COSMIC	0.000	Loss
CMGC_MAPK_JNK_MAPK10_ST	P01106	MYC	P53779	MAPK10	S204	S207P	207	Missense	distal	3	no	0.024	0.023	EPSD	COSMIC	0.000	Down-regulation
CMGC_MAPK_JNK_MAPK10_ST	P01106	MYC	P53779	MAPK10	S249	S250C	250	Missense	proximal	1	no	-0.003	0.000	EPSD	COSMIC	0.000	Gain
CMGC_MAPK_JNK_MAPK10_ST	P01106	MYC	P53779	MAPK10	S250	D251N	251	Missense	proximal	1	no	0.000	-0.001	EPSD	COSMIC;CCLE	0.000	Loss
CMGC_MAPK_JNK_MAPK10_ST	P01106	MYC	P53779	MAPK10	S250	S250I	250	Missense	central	0	yes	0.000	0.000	EPSD	COSMIC	0.000	Loss
CMGC_MAPK_JNK_MAPK10_ST	P01106	MYC	P53779	MAPK10	S250	S250C	250	Missense	central	0	yes	0.000	0.000	EPSD	COSMIC	0.000	Loss
CMGC_MAPK_JNK_MAPK10_ST	P01106	MYC	P53779	MAPK10	S250	D251E	251	Missense	proximal	1	no	0.000	-0.002	EPSD	COSMIC	0.000	Loss
CMGC_MAPK_JNK_MAPK10_ST	P01106	MYC	P53779	MAPK10	S250	S250R	250	Missense	central	0	yes	0.000	0.000	EPSD	COSMIC	0.000	Loss
CMGC_MAPK_JNK_MAPK10_ST	P01106	MYC	P53779	MAPK10	S281	P282A	282	Missense	proximal	1	no	0.023	-0.002	EPSD	COSMIC	0.000	Loss
CMGC_MAPK_JNK_MAPK10_ST	P01106	MYC	P53779	MAPK10	S281	S281F	281	Missense	central	0	yes	0.023	0.000	EPSD	COSMIC	0.000	Loss
CMGC_MAPK_JNK_MAPK10_ST	P01106	MYC	P53779	MAPK10	S293	S293C	293	Missense	central	0	yes	0.024	0.000	EPSD	COSMIC	0.000	Loss
CMGC_MAPK_JNK_MAPK10_ST	P01106	MYC	P53779	MAPK10	S293	S293R	293	Missense	central	0	yes	0.024	0.000	EPSD	COSMIC	0.000	Loss
CMGC_MAPK_JNK_MAPK10_ST	P01106	MYC	P53779	MAPK10	S344	S347F	347	Missense	distal	3	no	0.024	0.023	EPSD	COSMIC	0.000	Down-regulation
CMGC_MAPK_JNK_MAPK10_ST	P01106	MYC	P53779	MAPK10	T358	H359R	359	Missense	proximal	1	no	0.000	-0.001	EPSD	COSMIC	0.000	Loss
CMGC_MAPK_JNK_MAPK10_ST	P01106	MYC	P53779	MAPK10	T358	T358R	358	Missense	central	0	yes	0.000	0.000	EPSD	COSMIC	0.000	Loss
CMGC_MAPK_JNK_MAPK10_ST	P05067	APP	P53779	MAPK10	S573	D574Y	574	Missense	proximal	1	no	-0.001	0.000	EPSD	COSMIC	0.000	Gain
CMGC_MAPK_JNK_MAPK10_ST	P05067	APP	P53779	MAPK10	S587	P584Q	584	Missense	distal	-3	no	0.002	0.001	EPSD	COSMIC	0.000	Down-regulation
CMGC_MAPK_JNK_MAPK10_ST	P05067	APP	P53779	MAPK10	T598	E599D	599	Missense	proximal	1	no	-0.002	0.000	EPSD	COSMIC	0.000	Gain
CMGC_MAPK_JNK_MAPK10_ST	P05067	APP	P53779	MAPK10	T729	S730Y	730	Missense	proximal	1	no	-0.003	0.001	EPSD	COSMIC	0.000	Gain
CMGC_MAPK_JNK_MAPK10_ST	P38936	CDKN1A	P53779	MAPK10	S31	R32C	32	Missense	proximal	1	no	-0.001	0.000	EPSD	COSMIC	0.000	Gain
CMGC_MAPK_JNK_MAPK10_ST	P38936	CDKN1A	P53779	MAPK10	T57	T57R	57	Missense	central	0	yes	0.023	0.000	EPSD	COSMIC	0.000	Loss
CMGC_MAPK_JNK_MAPK10_ST	P54259	ATN1	P53779	MAPK10	S34	P35L	35	Missense	proximal	1	no	0.023	-0.002	EPSD	COSMIC	0.000	Loss
CMGC_MAPK_JNK_MAPK10_ST	P54259	ATN1	P53779	MAPK10	S103	D104N	104	Missense	proximal	1	no	0.000	-0.001	EPSD	COSMIC	0.000	Loss
CMGC_MAPK_JNK_MAPK10_ST	P54259	ATN1	P53779	MAPK10	S887	E888D	888	Missense	proximal	1	no	-0.003	0.000	EPSD	COSMIC	0.000	Gain
CMGC_MAPK_JNK_MAPK10_ST	P55957	BID	P53779	MAPK10	S65	H66L	66	Missense	proximal	1	no	0.000	-0.002	EPSD	COSMIC	0.000	Loss
CMGC_MAPK_JNK_MAPK10_ST	P55957	BID	P53779	MAPK10	S96	R99H	99	Missense	distal	3	no	0.000	-0.001	EPSD	COSMIC;CCLE	0.000	Loss
CMGC_MAPK_JNK_MAPK10_ST	P55957	BID	P53779	MAPK10	S96	M97V	97	Missense	proximal	1	no	0.000	-0.002	EPSD	COSMIC	0.000	Loss
CMGC_MAPK_JNK_MAPK10_ST	P55957	BID	P53779	MAPK10	S96	S96N	96	Missense	central	0	yes	0.000	0.000	EPSD	COSMIC	0.000	Loss
CMGC_MAPK_JNK_MAPK10_ST	O95644	NFATC1	P53779	MAPK10	S117	P118L	118	Missense	proximal	1	no	0.024	-0.002	EPSD	COSMIC	0.000	Loss
CMGC_MAPK_JNK_MAPK10_ST	O95644	NFATC1	P53779	MAPK10	S233	S233F	233	Missense	central	0	yes	0.023	0.000	EPSD	COSMIC	0.000	Loss
CMGC_MAPK_JNK_MAPK10_ST	O95644	NFATC1	P53779	MAPK10	S237	S237P	237	Missense	central	0	yes	0.024	0.000	EPSD	COSMIC	0.000	Loss
CMGC_MAPK_JNK_MAPK10_ST	O95644	NFATC1	P53779	MAPK10	T284	T284M	284	Missense	central	0	yes	0.023	0.000	EPSD	COSMIC	0.000	Loss
CMGC_MAPK_JNK_MAPK10_ST	O95644	NFATC1	P53779	MAPK10	S286	S286L	286	Missense	central	0	yes	0.023	0.000	EPSD	COSMIC;GDSC	0.000	Loss
CMGC_MAPK_JNK_MAPK10_ST	O95644	NFATC1	P53779	MAPK10	S286	P287L	287	Missense	proximal	1	no	0.023	-0.002	EPSD	COSMIC	0.000	Loss
CMGC_MAPK_JNK_MAPK10_ST	O95644	NFATC1	P53779	MAPK10	S406	S406F	406	Missense	central	0	yes	0.001	0.000	EPSD	COSMIC;CCLE	0.000	Loss
CMGC_MAPK_JNK_MAPK10_ST	O95644	NFATC1	P53779	MAPK10	S409	P410L	410	Missense	proximal	1	no	0.023	-0.003	EPSD	COSMIC	0.000	Loss
CMGC_MAPK_JNK_MAPK10_ST	O95644	NFATC1	P53779	MAPK10	T504	T505P	505	Missense	proximal	1	no	-0.002	0.023	EPSD	COSMIC	0.000	Gain
CMGC_MAPK_JNK_MAPK10_ST	O95644	NFATC1	P53779	MAPK10	S723	V718L	718	Missense	distal	-5	no	0.022	0.023	EPSD	COSMIC	0.000	Up-regulation
CMGC_MAPK_JNK_MAPK10_ST	O95644	NFATC1	P53779	MAPK10	S723	P724L	724	Missense	proximal	1	no	0.022	-0.003	EPSD	COSMIC	0.000	Loss
CMGC_MAPK_JNK_MAPK10_ST	O95644	NFATC1	P53779	MAPK10	S813	S813L	813	Missense	central	0	yes	0.023	0.000	EPSD	COSMIC	0.000	Loss
CMGC_MAPK_JNK_MAPK10_ST	Q06481	APLP2	P53779	MAPK10	S213	S213L	213	Missense	central	0	yes	0.000	0.000	EPSD	COSMIC	0.000	Loss
Other_NEK_NEK1_NEK1_ST	P21796	VDAC1	Q96PY6	NEK1	T258	L251P	251	Missense	distal	-7	no	2.700	2.444	EPSD	COSMIC	2.106	Down-regulation
Other_NEK_NEK1_NEK1_ST	P40337	VHL	Q96PY6	NEK1	S80	V84L	84	Missense	distal	4	no	1.943	2.187	EPSD	COSMIC	2.106	Gain
Other_NEK_NEK1_NEK1_ST	P40337	VHL	Q96PY6	NEK1	S80	V84M	84	Missense	distal	4	no	1.943	2.143	EPSD	COSMIC	2.106	Gain
Other_NEK_NEK1_NEK1_ST	P40337	VHL	Q96PY6	NEK1	T100	Q96P	96	Missense	distal	-4	no	4.611	4.621	EPSD;PhosphoSitePlus	COSMIC	2.106	Up-regulation
Other_NEK_NEK1_NEK1_ST	P40337	VHL	Q96PY6	NEK1	T100	R107C	107	Missense	distal	7	no	4.611	4.609	EPSD;PhosphoSitePlus	COSMIC	2.106	Down-regulation
Other_NEK_NEK1_NEK1_ST	P40337	VHL	Q96PY6	NEK1	T100	G93R	93	Missense	distal	-7	no	4.611	4.399	EPSD;PhosphoSitePlus	COSMIC	2.106	Down-regulation
Other_NEK_NEK1_NEK1_ST	P40337	VHL	Q96PY6	NEK1	T100	E94K	94	Missense	distal	-6	no	4.611	4.650	EPSD;PhosphoSitePlus	COSMIC	2.106	Up-regulation
Other_NEK_NEK1_NEK1_ST	P40337	VHL	Q96PY6	NEK1	T100	G106D	106	Missense	distal	6	no	4.611	4.623	EPSD;PhosphoSitePlus	COSMIC	2.106	Up-regulation
Other_NEK_NEK1_NEK1_ST	P40337	VHL	Q96PY6	NEK1	T100	L101R	101	Missense	proximal	1	no	4.611	4.564	EPSD;PhosphoSitePlus	COSMIC	2.106	Down-regulation
Other_NEK_NEK1_NEK1_ST	P40337	VHL	Q96PY6	NEK1	T100	P99L	99	Missense	proximal	-1	no	4.611	4.731	EPSD;PhosphoSitePlus	COSMIC	2.106	Up-regulation
Other_NEK_NEK1_NEK1_ST	P40337	VHL	Q96PY6	NEK1	T100	G93V	93	Missense	distal	-7	no	4.611	4.199	EPSD;PhosphoSitePlus	COSMIC	2.106	Down-regulation
Other_NEK_NEK1_NEK1_ST	P40337	VHL	Q96PY6	NEK1	T100	T105M	105	Missense	distal	5	no	4.611	4.631	EPSD;PhosphoSitePlus	COSMIC	2.106	Up-regulation
Other_NEK_NEK1_NEK1_ST	P40337	VHL	Q96PY6	NEK1	T100	Y98N	98	Missense	proximal	-2	no	4.611	4.592	EPSD;PhosphoSitePlus	COSMIC	2.106	Down-regulation
Other_NEK_NEK1_NEK1_ST	P40337	VHL	Q96PY6	NEK1	T100	G106A	106	Missense	distal	6	no	4.611	4.553	EPSD;PhosphoSitePlus	COSMIC	2.106	Down-regulation
Other_NEK_NEK1_NEK1_ST	P40337	VHL	Q96PY6	NEK1	T100	G93S	93	Missense	distal	-7	no	4.611	4.128	EPSD;PhosphoSitePlus	COSMIC	2.106	Down-regulation
Other_NEK_NEK1_NEK1_ST	P40337	VHL	Q96PY6	NEK1	T100	T100A	100	Missense	central	0	yes	4.611	0.000	EPSD;PhosphoSitePlus	COSMIC	2.106	Loss
Other_NEK_NEK1_NEK1_ST	P40337	VHL	Q96PY6	NEK1	T100	P95Q	95	Missense	distal	-5	no	4.611	4.625	EPSD;PhosphoSitePlus	COSMIC	2.106	Up-regulation
Other_NEK_NEK1_NEK1_ST	P40337	VHL	Q96PY6	NEK1	T100	T105K	105	Missense	distal	5	no	4.611	4.588	EPSD;PhosphoSitePlus	COSMIC	2.106	Down-regulation
Other_NEK_NEK1_NEK1_ST	P40337	VHL	Q96PY6	NEK1	T100	Y98S	98	Missense	proximal	-2	no	4.611	4.429	EPSD;PhosphoSitePlus	COSMIC	2.106	Down-regulation
Other_NEK_NEK1_NEK1_ST	P40337	VHL	Q96PY6	NEK1	T100	T105P	105	Missense	distal	5	no	4.611	4.680	EPSD;PhosphoSitePlus	COSMIC	2.106	Up-regulation
Other_NEK_NEK1_NEK1_ST	P40337	VHL	Q96PY6	NEK1	T100	Y98F	98	Missense	proximal	-2	no	4.611	4.583	EPSD;PhosphoSitePlus	COSMIC	2.106	Down-regulation
Other_NEK_NEK1_NEK1_ST	P40337	VHL	Q96PY6	NEK1	T100	Q96H	96	Missense	distal	-4	no	4.611	4.488	EPSD;PhosphoSitePlus	COSMIC	2.106	Down-regulation
Other_NEK_NEK1_NEK1_ST	P40337	VHL	Q96PY6	NEK1	T100	P97L	97	Missense	distal	-3	no	4.611	4.349	EPSD;PhosphoSitePlus	COSMIC	2.106	Down-regulation
Other_NEK_NEK1_NEK1_ST	P40337	VHL	Q96PY6	NEK1	T100	Y98C	98	Missense	proximal	-2	no	4.611	4.624	EPSD;PhosphoSitePlus	COSMIC	2.106	Up-regulation
Other_NEK_NEK1_NEK1_ST	P40337	VHL	Q96PY6	NEK1	T100	P102S	102	Missense	proximal	2	no	4.611	4.532	EPSD;PhosphoSitePlus	COSMIC	2.106	Down-regulation
Other_NEK_NEK1_NEK1_ST	P40337	VHL	Q96PY6	NEK1	T100	G106V	106	Missense	distal	6	no	4.611	4.572	EPSD;PhosphoSitePlus	COSMIC	2.106	Down-regulation
Other_NEK_NEK1_NEK1_ST	P40337	VHL	Q96PY6	NEK1	T100	P95R	95	Missense	distal	-5	no	4.611	4.680	EPSD;PhosphoSitePlus	COSMIC	2.106	Up-regulation
Other_NEK_NEK1_NEK1_ST	P40337	VHL	Q96PY6	NEK1	T100	P102L	102	Missense	proximal	2	no	4.611	4.661	EPSD;PhosphoSitePlus	COSMIC	2.106	Up-regulation
Other_NEK_NEK1_NEK1_ST	P40337	VHL	Q96PY6	NEK1	T100	G93D	93	Missense	distal	-7	no	4.611	4.667	EPSD;PhosphoSitePlus	COSMIC	2.106	Up-regulation
Other_NEK_NEK1_NEK1_ST	P40337	VHL	Q96PY6	NEK1	T100	P97S	97	Missense	distal	-3	no	4.611	4.417	EPSD;PhosphoSitePlus	COSMIC	2.106	Down-regulation
Other_NEK_NEK1_NEK1_ST	P40337	VHL	Q96PY6	NEK1	T100	R107G	107	Missense	distal	7	no	4.611	4.612	EPSD;PhosphoSitePlus	COSMIC	2.106	Up-regulation
Other_NEK_NEK1_NEK1_ST	P40337	VHL	Q96PY6	NEK1	T100	L101Q	101	Missense	proximal	1	no	4.611	4.484	EPSD;PhosphoSitePlus	COSMIC	2.106	Down-regulation
Other_NEK_NEK1_NEK1_ST	P40337	VHL	Q96PY6	NEK1	T100	P102A	102	Missense	proximal	2	no	4.611	4.565	EPSD;PhosphoSitePlus	COSMIC	2.106	Down-regulation
Other_NEK_NEK1_NEK1_ST	P40337	VHL	Q96PY6	NEK1	T105	R107C	107	Missense	proximal	2	no	4.846	4.837	PhosphoSitePlus;EPSD	COSMIC	2.106	Down-regulation
Other_NEK_NEK1_NEK1_ST	P40337	VHL	Q96PY6	NEK1	T105	G106D	106	Missense	proximal	1	no	4.846	4.803	PhosphoSitePlus;EPSD	COSMIC	2.106	Down-regulation
Other_NEK_NEK1_NEK1_ST	P40337	VHL	Q96PY6	NEK1	T105	H110Y	110	Missense	distal	5	no	4.846	4.820	PhosphoSitePlus;EPSD	COSMIC	2.106	Down-regulation
Other_NEK_NEK1_NEK1_ST	P40337	VHL	Q96PY6	NEK1	T105	H110N	110	Missense	distal	5	no	4.846	4.754	PhosphoSitePlus;EPSD	COSMIC	2.106	Down-regulation
Other_NEK_NEK1_NEK1_ST	P40337	VHL	Q96PY6	NEK1	T105	L101R	101	Missense	distal	-4	no	4.846	4.762	PhosphoSitePlus;EPSD	COSMIC	2.106	Down-regulation
Other_NEK_NEK1_NEK1_ST	P40337	VHL	Q96PY6	NEK1	T105	Y112D	112	Missense	distal	7	no	4.846	4.852	PhosphoSitePlus;EPSD	COSMIC	2.106	Up-regulation
Other_NEK_NEK1_NEK1_ST	P40337	VHL	Q96PY6	NEK1	T105	I109S	109	Missense	distal	4	no	4.846	4.458	PhosphoSitePlus;EPSD	COSMIC	2.106	Down-regulation
Other_NEK_NEK1_NEK1_ST	P40337	VHL	Q96PY6	NEK1	T105	H110R	110	Missense	distal	5	no	4.846	4.736	PhosphoSitePlus;EPSD	COSMIC	2.106	Down-regulation
Other_NEK_NEK1_NEK1_ST	P40337	VHL	Q96PY6	NEK1	T105	P99L	99	Missense	distal	-6	no	4.846	4.909	PhosphoSitePlus;EPSD	COSMIC	2.106	Up-regulation
Other_NEK_NEK1_NEK1_ST	P40337	VHL	Q96PY6	NEK1	T105	T105M	105	Missense	central	0	yes	4.846	0.000	PhosphoSitePlus;EPSD	COSMIC	2.106	Loss
Other_NEK_NEK1_NEK1_ST	P40337	VHL	Q96PY6	NEK1	T105	I109F	109	Missense	distal	4	no	4.846	4.482	PhosphoSitePlus;EPSD	COSMIC	2.106	Down-regulation
Other_NEK_NEK1_NEK1_ST	P40337	VHL	Q96PY6	NEK1	T105	Y98N	98	Missense	distal	-7	no	4.846	4.452	PhosphoSitePlus;EPSD	COSMIC	2.106	Down-regulation
Other_NEK_NEK1_NEK1_ST	P40337	VHL	Q96PY6	NEK1	T105	G106A	106	Missense	proximal	1	no	4.846	4.586	PhosphoSitePlus;EPSD	COSMIC	2.106	Down-regulation
Other_NEK_NEK1_NEK1_ST	P40337	VHL	Q96PY6	NEK1	T105	T100A	100	Missense	distal	-5	no	4.846	4.758	PhosphoSitePlus;EPSD	COSMIC	2.106	Down-regulation
Other_NEK_NEK1_NEK1_ST	P40337	VHL	Q96PY6	NEK1	T105	T105K	105	Missense	central	0	yes	4.846	0.000	PhosphoSitePlus;EPSD	COSMIC	2.106	Loss
Other_NEK_NEK1_NEK1_ST	P40337	VHL	Q96PY6	NEK1	T105	Y98S	98	Missense	distal	-7	no	4.846	4.389	PhosphoSitePlus;EPSD	COSMIC	2.106	Down-regulation
Other_NEK_NEK1_NEK1_ST	P40337	VHL	Q96PY6	NEK1	T105	T105P	105	Missense	central	0	yes	4.846	0.000	PhosphoSitePlus;EPSD	COSMIC	2.106	Loss
Other_NEK_NEK1_NEK1_ST	P40337	VHL	Q96PY6	NEK1	T105	Y98F	98	Missense	distal	-7	no	4.846	4.640	PhosphoSitePlus;EPSD	COSMIC	2.106	Down-regulation
Other_NEK_NEK1_NEK1_ST	P40337	VHL	Q96PY6	NEK1	T105	Y98C	98	Missense	distal	-7	no	4.846	4.674	PhosphoSitePlus;EPSD	COSMIC	2.106	Down-regulation
Other_NEK_NEK1_NEK1_ST	P40337	VHL	Q96PY6	NEK1	T105	P102S	102	Missense	distal	-3	no	4.846	4.652	PhosphoSitePlus;EPSD	COSMIC	2.106	Down-regulation
Other_NEK_NEK1_NEK1_ST	P40337	VHL	Q96PY6	NEK1	T105	G106V	106	Missense	proximal	1	no	4.846	4.655	PhosphoSitePlus;EPSD	COSMIC	2.106	Down-regulation
Other_NEK_NEK1_NEK1_ST	P40337	VHL	Q96PY6	NEK1	T105	P102L	102	Missense	distal	-3	no	4.846	4.584	PhosphoSitePlus;EPSD	COSMIC	2.106	Down-regulation
Other_NEK_NEK1_NEK1_ST	P40337	VHL	Q96PY6	NEK1	T105	R107G	107	Missense	proximal	2	no	4.846	4.941	PhosphoSitePlus;EPSD	COSMIC	2.106	Up-regulation
Other_NEK_NEK1_NEK1_ST	P40337	VHL	Q96PY6	NEK1	T105	L101Q	101	Missense	distal	-4	no	4.846	4.924	PhosphoSitePlus;EPSD	COSMIC	2.106	Up-regulation
Other_NEK_NEK1_NEK1_ST	P40337	VHL	Q96PY6	NEK1	T105	S111P	111	Missense	distal	6	no	4.846	4.807	PhosphoSitePlus;EPSD	COSMIC	2.106	Down-regulation
Other_NEK_NEK1_NEK1_ST	P40337	VHL	Q96PY6	NEK1	T105	P102A	102	Missense	distal	-3	no	4.846	4.732	PhosphoSitePlus;EPSD	COSMIC	2.106	Down-regulation
Other_NEK_NEK1_NEK1_ST	P40337	VHL	Q96PY6	NEK1	S168	V166F	166	Missense	proximal	-2	no	4.486	4.485	EPSD;PhosphoSitePlus	COSMIC	2.106	Down-regulation
Other_NEK_NEK1_NEK1_ST	P40337	VHL	Q96PY6	NEK1	S168	C162W	162	Missense	distal	-6	no	4.486	4.450	EPSD;PhosphoSitePlus	COSMIC	2.106	Down-regulation
Other_NEK_NEK1_NEK1_ST	P40337	VHL	Q96PY6	NEK1	S168	K171N	171	Missense	distal	3	no	4.486	4.455	EPSD;PhosphoSitePlus	COSMIC	2.106	Down-regulation
Other_NEK_NEK1_NEK1_ST	P40337	VHL	Q96PY6	NEK1	S168	L163P	163	Missense	distal	-5	no	4.486	4.468	EPSD;PhosphoSitePlus	COSMIC	2.106	Down-regulation
Other_NEK_NEK1_NEK1_ST	P40337	VHL	Q96PY6	NEK1	S168	R167Q	167	Missense	proximal	-1	no	4.486	4.410	EPSD;PhosphoSitePlus	COSMIC	2.106	Down-regulation
Other_NEK_NEK1_NEK1_ST	P40337	VHL	Q96PY6	NEK1	S168	Q164R	164	Missense	distal	-4	no	4.486	4.324	EPSD;PhosphoSitePlus	COSMIC	2.106	Down-regulation
Other_NEK_NEK1_NEK1_ST	P40337	VHL	Q96PY6	NEK1	S168	V166D	166	Missense	proximal	-2	no	4.486	4.505	EPSD;PhosphoSitePlus	COSMIC	2.106	Up-regulation
Other_NEK_NEK1_NEK1_ST	P40337	VHL	Q96PY6	NEK1	S168	V166G	166	Missense	proximal	-2	no	4.486	4.564	EPSD;PhosphoSitePlus	COSMIC	2.106	Up-regulation
Other_NEK_NEK1_NEK1_ST	P40337	VHL	Q96PY6	NEK1	S168	Y175D	175	Missense	distal	7	no	4.486	4.492	EPSD;PhosphoSitePlus	COSMIC	2.106	Up-regulation
Other_NEK_NEK1_NEK1_ST	P40337	VHL	Q96PY6	NEK1	S168	R161G	161	Missense	distal	-7	no	4.486	4.698	EPSD;PhosphoSitePlus	COSMIC	2.106	Up-regulation
Other_NEK_NEK1_NEK1_ST	P40337	VHL	Q96PY6	NEK1	S168	Q164P	164	Missense	distal	-4	no	4.486	4.496	EPSD;PhosphoSitePlus	COSMIC	2.106	Up-regulation
Other_NEK_NEK1_NEK1_ST	P40337	VHL	Q96PY6	NEK1	S168	C162Y	162	Missense	distal	-6	no	4.486	4.489	EPSD;PhosphoSitePlus	COSMIC	2.106	Up-regulation
Other_NEK_NEK1_NEK1_ST	P40337	VHL	Q96PY6	NEK1	S168	L163H	163	Missense	distal	-5	no	4.486	4.505	EPSD;PhosphoSitePlus	COSMIC	2.106	Up-regulation
Other_NEK_NEK1_NEK1_ST	P40337	VHL	Q96PY6	NEK1	S168	V170D	170	Missense	proximal	2	no	4.486	4.579	EPSD;PhosphoSitePlus	COSMIC	2.106	Up-regulation
Other_NEK_NEK1_NEK1_ST	P40337	VHL	Q96PY6	NEK1	S168	P172T	172	Missense	distal	4	no	4.486	4.416	EPSD;PhosphoSitePlus	COSMIC	2.106	Down-regulation
Other_NEK_NEK1_NEK1_ST	P40337	VHL	Q96PY6	NEK1	S168	V165I	165	Missense	distal	-3	no	4.486	4.610	EPSD;PhosphoSitePlus	COSMIC	2.106	Up-regulation
Other_NEK_NEK1_NEK1_ST	P40337	VHL	Q96PY6	NEK1	S168	R161L	161	Missense	distal	-7	no	4.486	4.826	EPSD;PhosphoSitePlus	COSMIC	2.106	Up-regulation
Other_NEK_NEK1_NEK1_ST	P40337	VHL	Q96PY6	NEK1	S168	V170A	170	Missense	proximal	2	no	4.486	4.527	EPSD;PhosphoSitePlus	COSMIC	2.106	Up-regulation
Other_NEK_NEK1_NEK1_ST	P40337	VHL	Q96PY6	NEK1	S168	V165L	165	Missense	distal	-3	no	4.486	4.449	EPSD;PhosphoSitePlus	COSMIC	2.106	Down-regulation
Other_NEK_NEK1_NEK1_ST	P40337	VHL	Q96PY6	NEK1	S168	Q164L	164	Missense	distal	-4	no	4.486	4.408	EPSD;PhosphoSitePlus	COSMIC	2.106	Down-regulation
Other_NEK_NEK1_NEK1_ST	P40337	VHL	Q96PY6	NEK1	S168	E173Q	173	Missense	distal	5	no	4.486	4.555	EPSD;PhosphoSitePlus	COSMIC	2.106	Up-regulation
Other_NEK_NEK1_NEK1_ST	P40337	VHL	Q96PY6	NEK1	S168	Q164H	164	Missense	distal	-4	no	4.486	4.362	EPSD;PhosphoSitePlus	COSMIC	2.106	Down-regulation
Other_NEK_NEK1_NEK1_ST	P40337	VHL	Q96PY6	NEK1	S168	V166I	166	Missense	proximal	-2	no	4.486	4.533	EPSD;PhosphoSitePlus	COSMIC	2.106	Up-regulation
Other_NEK_NEK1_NEK1_ST	P40337	VHL	Q96PY6	NEK1	S168	S168C	168	Missense	central	0	yes	4.486	0.000	EPSD;PhosphoSitePlus	COSMIC	2.106	Loss
Other_NEK_NEK1_NEK1_ST	P40337	VHL	Q96PY6	NEK1	S168	L163R	163	Missense	distal	-5	no	4.486	4.538	EPSD;PhosphoSitePlus	COSMIC	2.106	Up-regulation
Other_NEK_NEK1_NEK1_ST	P40337	VHL	Q96PY6	NEK1	S168	N174D	174	Missense	distal	6	no	4.486	4.388	EPSD;PhosphoSitePlus	COSMIC	2.106	Down-regulation
Other_NEK_NEK1_NEK1_ST	P40337	VHL	Q96PY6	NEK1	S168	L169Q	169	Missense	proximal	1	no	4.486	4.358	EPSD;PhosphoSitePlus	COSMIC	2.106	Down-regulation
Other_NEK_NEK1_NEK1_ST	P40337	VHL	Q96PY6	NEK1	S168	L163F	163	Missense	distal	-5	no	4.486	4.446	EPSD;PhosphoSitePlus	COSMIC	2.106	Down-regulation
Other_NEK_NEK1_NEK1_ST	P40337	VHL	Q96PY6	NEK1	S168	P172S	172	Missense	distal	4	no	4.486	4.283	EPSD;PhosphoSitePlus	COSMIC	2.106	Down-regulation
Other_NEK_NEK1_NEK1_ST	P40337	VHL	Q96PY6	NEK1	S183	D187V	187	Missense	distal	4	no	3.991	3.910	EPSD;PhosphoSitePlus	COSMIC	2.106	Down-regulation
Other_NEK_NEK1_NEK1_ST	P40337	VHL	Q96PY6	NEK1	S183	E186K	186	Missense	distal	3	no	3.991	4.042	EPSD;PhosphoSitePlus	COSMIC	2.106	Up-regulation
Other_NEK_NEK1_NEK1_ST	P40337	VHL	Q96PY6	NEK1	S183	L188V	188	Missense	distal	5	no	3.991	3.859	EPSD;PhosphoSitePlus	COSMIC	2.106	Down-regulation
Other_NEK_NEK1_NEK1_ST	P40337	VHL	Q96PY6	NEK1	S183	E189K	189	Missense	distal	6	no	3.991	4.027	EPSD;PhosphoSitePlus	COSMIC	2.106	Up-regulation
Other_NEK_NEK1_NEK1_ST	P40337	VHL	Q96PY6	NEK1	S183	L184R	184	Missense	proximal	1	no	3.991	3.943	EPSD;PhosphoSitePlus	COSMIC	2.106	Down-regulation
Other_NEK_NEK1_NEK1_ST	P40337	VHL	Q96PY6	NEK1	S183	I180V	180	Missense	distal	-3	no	3.991	3.866	EPSD;PhosphoSitePlus	COSMIC	2.106	Down-regulation
Other_NEK_NEK1_NEK1_ST	P40337	VHL	Q96PY6	NEK1	S183	E189V	189	Missense	distal	6	no	3.991	3.962	EPSD;PhosphoSitePlus	COSMIC	2.106	Down-regulation
Other_NEK_NEK1_NEK1_ST	P40337	VHL	Q96PY6	NEK1	S183	Y185F	185	Missense	proximal	2	no	3.991	3.956	EPSD;PhosphoSitePlus	COSMIC	2.106	Down-regulation
Other_NEK_NEK1_NEK1_ST	P40337	VHL	Q96PY6	NEK1	S183	D187N	187	Missense	distal	4	no	3.991	3.746	EPSD;PhosphoSitePlus	COSMIC	2.106	Down-regulation
Other_NEK_NEK1_NEK1_ST	P40337	VHL	Q96PY6	NEK1	S183	S183L	183	Missense	central	0	yes	3.991	0.000	EPSD;PhosphoSitePlus	COSMIC	2.106	Loss
Other_NEK_NEK1_NEK1_ST	P40337	VHL	Q96PY6	NEK1	S183	V181I	181	Missense	proximal	-2	no	3.991	4.038	EPSD;PhosphoSitePlus	COSMIC	2.106	Up-regulation
Other_NEK_NEK1_NEK1_ST	P40337	VHL	Q96PY6	NEK1	S183	L184H	184	Missense	proximal	1	no	3.991	3.971	EPSD;PhosphoSitePlus	COSMIC	2.106	Down-regulation
Other_NEK_NEK1_NEK1_ST	P40337	VHL	Q96PY6	NEK1	S183	I180N	180	Missense	distal	-3	no	3.991	4.013	EPSD;PhosphoSitePlus	COSMIC;GDSC;CCLE	2.106	Up-regulation
Other_NEK_NEK1_NEK1_ST	P40337	VHL	Q96PY6	NEK1	S183	L178R	178	Missense	distal	-5	no	3.991	4.043	EPSD;PhosphoSitePlus	COSMIC	2.106	Up-regulation
Other_NEK_NEK1_NEK1_ST	P40337	VHL	Q96PY6	NEK1	S183	L188Q	188	Missense	distal	5	no	3.991	3.897	EPSD;PhosphoSitePlus	COSMIC	2.106	Down-regulation
Other_NEK_NEK1_NEK1_ST	P40337	VHL	Q96PY6	NEK1	S183	R176W	176	Missense	distal	-7	no	3.991	3.904	EPSD;PhosphoSitePlus	COSMIC	2.106	Down-regulation
Other_NEK_NEK1_NEK1_ST	P40337	VHL	Q96PY6	NEK1	S183	R182M	182	Missense	proximal	-1	no	3.991	4.046	EPSD;PhosphoSitePlus	COSMIC	2.106	Up-regulation
Other_NEK_NEK1_NEK1_ST	P40337	VHL	Q96PY6	NEK1	S183	L178M	178	Missense	distal	-5	no	3.991	3.981	EPSD;PhosphoSitePlus	COSMIC	2.106	Down-regulation
Other_NEK_NEK1_NEK1_ST	P40337	VHL	Q96PY6	NEK1	S183	R182K	182	Missense	proximal	-1	no	3.991	3.818	EPSD;PhosphoSitePlus	COSMIC	2.106	Down-regulation
Other_NEK_NEK1_NEK1_ST	P40337	VHL	Q96PY6	NEK1	S183	D179N	179	Missense	distal	-4	no	3.991	4.078	EPSD;PhosphoSitePlus	COSMIC	2.106	Up-regulation
Other_NEK_NEK1_NEK1_ST	P40337	VHL	Q96PY6	NEK1	S183	E189Q	189	Missense	distal	6	no	3.991	3.970	EPSD;PhosphoSitePlus	COSMIC	2.106	Down-regulation
Other_NEK_NEK1_NEK1_ST	P40337	VHL	Q96PY6	NEK1	S183	R176K	176	Missense	distal	-7	no	3.991	3.762	EPSD;PhosphoSitePlus	COSMIC	2.106	Down-regulation
Other_NEK_NEK1_NEK1_ST	P40337	VHL	Q96PY6	NEK1	T202	L198P	198	Missense	distal	-4	no	3.643	3.731	EPSD;PhosphoSitePlus	COSMIC	2.106	Up-regulation
Other_NEK_NEK1_NEK1_ST	P40337	VHL	Q96PY6	NEK1	T202	L201P	201	Missense	proximal	-1	no	3.643	3.524	EPSD;PhosphoSitePlus	COSMIC	2.106	Down-regulation
Other_NEK_NEK1_NEK1_ST	P40337	VHL	Q96PY6	NEK1	T202	R200W	200	Missense	proximal	-2	no	3.643	3.651	EPSD;PhosphoSitePlus	COSMIC	2.106	Up-regulation
Other_NEK_NEK1_NEK1_ST	P40337	VHL	Q96PY6	NEK1	T202	H208N	208	Missense	distal	6	no	3.643	3.729	EPSD;PhosphoSitePlus	COSMIC	2.106	Up-regulation
Other_NEK_NEK1_NEK1_ST	P40337	VHL	Q96PY6	NEK1	T202	A207V	207	Missense	distal	5	no	3.643	3.604	EPSD;PhosphoSitePlus	COSMIC	2.106	Down-regulation
Other_NEK_NEK1_NEK1_ST	P40337	VHL	Q96PY6	NEK1	T202	A207T	207	Missense	distal	5	no	3.643	3.607	EPSD;PhosphoSitePlus	COSMIC	2.106	Down-regulation
Other_NEK_NEK1_NEK1_ST	P40337	VHL	Q96PY6	NEK1	T202	E199G	199	Missense	distal	-3	no	3.643	3.469	EPSD;PhosphoSitePlus	COSMIC	2.106	Down-regulation
Other_NEK_NEK1_NEK1_ST	P40337	VHL	Q96PY6	NEK1	T202	R205H	205	Missense	distal	3	no	3.643	3.604	EPSD;PhosphoSitePlus	COSMIC	2.106	Down-regulation
Other_NEK_NEK1_NEK1_ST	P40337	VHL	Q96PY6	NEK1	T202	Q195R	195	Missense	distal	-7	no	3.643	3.676	EPSD;PhosphoSitePlus	COSMIC	2.106	Up-regulation
Other_NEK_NEK1_NEK1_ST	P40337	VHL	Q96PY6	NEK1	T202	E204K	204	Missense	proximal	2	no	3.643	3.606	EPSD;PhosphoSitePlus	COSMIC	2.106	Down-regulation
Other_NEK_NEK1_NEK1_ST	P40337	VHL	Q96PY6	NEK1	T202	E204G	204	Missense	proximal	2	no	3.643	3.784	EPSD;PhosphoSitePlus	COSMIC	2.106	Up-regulation
Other_NEK_NEK1_NEK1_ST	P40337	VHL	Q96PY6	NEK1	T202	E204D	204	Missense	proximal	2	no	3.643	3.689	EPSD;PhosphoSitePlus	COSMIC	2.106	Up-regulation
Other_NEK_NEK1_NEK1_ST	P40337	VHL	Q96PY6	NEK1	T202	L198R	198	Missense	distal	-4	no	3.643	3.559	EPSD;PhosphoSitePlus	COSMIC	2.106	Down-regulation
Other_NEK_NEK1_NEK1_ST	Q92698	RAD54L	Q96PY6	NEK1	S176	S170I	170	Missense	distal	-6	no	2.052	2.159	EPSD	COSMIC	2.106	Gain
Other_NEK_NEK1_NEK1_ST	Q92698	RAD54L	Q96PY6	NEK1	S572	K574R	574	Missense	proximal	2	no	4.189	4.271	PhosphoSitePlus	COSMIC	2.106	Up-regulation
Other_NEK_NEK1_NEK1_ST	Q92698	RAD54L	Q96PY6	NEK1	S572	G576V	576	Missense	distal	4	no	4.189	3.850	PhosphoSitePlus	COSMIC	2.106	Down-regulation
Other_NEK_NEK1_NEK1_ST	Q92698	RAD54L	Q96PY6	NEK1	S572	G577S	577	Missense	distal	5	no	4.189	4.005	PhosphoSitePlus	COSMIC	2.106	Down-regulation
Other_NEK_NEK1_NEK1_ST	Q92698	RAD54L	Q96PY6	NEK1	S572	G579V	579	Missense	distal	7	no	4.189	4.150	PhosphoSitePlus	COSMIC	2.106	Down-regulation
Other_NEK_NEK1_NEK1_ST	O14777	NDC80	Q96PY6	NEK1	T34	T31A	31	Missense	distal	-3	no	2.401	2.477	EPSD	COSMIC	2.106	Up-regulation
Other_NEK_NEK1_NEK1_ST	O14777	NDC80	Q96PY6	NEK1	S165	A163T	163	Missense	proximal	-2	no	4.395	4.267	PhosphoSitePlus	COSMIC	2.106	Down-regulation
CMGC_CDK_CCRK_CDK20_ST	P24941	CDK2	Q8IZL9	CDK20	T160	P155S	155	Missense	distal	-5	no	5.811	5.702	PhosphoSitePlus	COSMIC	1.958	Down-regulation
CMGC_CDK_CCRK_CDK20_ST	P24941	CDK2	Q8IZL9	CDK20	T160	V164L	164	Missense	distal	4	no	5.811	5.783	PhosphoSitePlus	COSMIC	1.958	Down-regulation
CMGC_CDK_CCRK_CDK20_ST	P24941	CDK2	Q8IZL9	CDK20	T221	R217W	217	Missense	distal	-4	no	2.458	2.462	EPSD	COSMIC	1.958	Up-regulation
CMGC_CDK_CCRK_CDK20_ST	P24941	CDK2	Q8IZL9	CDK20	T221	R217L	217	Missense	distal	-4	no	2.458	2.465	EPSD	COSMIC	1.958	Up-regulation
CMGC_CDK_CCRK_CDK20_ST	P24941	CDK2	Q8IZL9	CDK20	T221	V226M	226	Missense	distal	5	no	2.458	2.683	EPSD	COSMIC	1.958	Up-regulation
CMGC_CDK_CCRK_CDK20_ST	P24941	CDK2	Q8IZL9	CDK20	T221	R214W	214	Missense	distal	-7	no	2.458	2.505	EPSD	COSMIC	1.958	Up-regulation
TK_Axl_AXL_Y	Q92556	ELMO1	P30530	AXL	Y720	P717T	717	Missense	distal	-3	no	0.006	0.005	PhosphoSitePlus;EPSD	COSMIC	0.002	Down-regulation
TK_Axl_AXL_Y	P08631	HCK	P30530	AXL	Y330	Y330H	330	Missense	central	0	yes	0.004	0.000	EPSD	COSMIC	0.002	Loss
TK_Axl_AXL_Y	P42229	STAT5A	P30530	AXL	Y682	Y682C	682	Missense	central	0	yes	0.002	0.000	EPSD	COSMIC	0.002	Loss
TK_Axl_AXL_Y	P42229	STAT5A	P30530	AXL	Y682	A688D	688	Missense	distal	6	no	0.002	0.003	EPSD	COSMIC	0.002	Up-regulation
TK_Axl_AXL_Y	P51692	STAT5B	P30530	AXL	Y665	Y665F	665	Missense	central	0	yes	0.003	0.000	EPSD	COSMIC	0.002	Loss
TK_Axl_AXL_Y	P40763	STAT3	P30530	AXL	Y705	G700R	700	Missense	distal	-5	no	0.006	0.005	PhosphoSitePlus	COSMIC	0.002	Down-regulation
TK_Axl_AXL_Y	P12931	SRC	P30530	AXL	Y338	T341A	341	Missense	distal	3	no	0.004	0.003	EPSD	COSMIC	0.002	Down-regulation
TK_Axl_AXL_Y	P12931	SRC	P30530	AXL	Y338	T341M	341	Missense	distal	3	no	0.004	0.003	EPSD	COSMIC	0.002	Down-regulation
TK_Axl_AXL_Y	P12931	SRC	P30530	AXL	Y419	Y419H	419	Missense	central	0	yes	0.011	0.000	PhosphoSitePlus	COSMIC	0.002	Loss
TK_Axl_AXL_Y	P12931	SRC	P30530	AXL	Y439	Y439S	439	Missense	central	0	yes	0.002	0.000	EPSD	COSMIC	0.002	Loss
TK_Axl_AXL_Y	P06239	LCK	P30530	AXL	Y51	P57L	57	Missense	distal	6	no	0.001	0.002	EPSD	COSMIC	0.002	Gain
TK_Axl_AXL_Y	P06241	FYN	P30530	AXL	Y420	R413Q	413	Missense	distal	-7	no	0.011	0.010	PhosphoSitePlus	COSMIC	0.002	Down-regulation
TK_Axl_AXL_Y	P06241	FYN	P30530	AXL	Y440	T433M	433	Missense	distal	-7	no	0.002	0.001	EPSD	COSMIC	0.002	Loss
TK_Axl_AXL_Y	P06241	FYN	P30530	AXL	Y515	Y515C	515	Missense	central	0	yes	0.002	0.000	EPSD	COSMIC;GDSC;CCLE	0.002	Loss
TK_Axl_AXL_Y	P07947	YES1	P30530	AXL	Y32	P36L	36	Missense	distal	4	no	0.004	0.003	EPSD	COSMIC	0.002	Down-regulation
CAMK_DAPK_DAPK_DAPK3_ST	Q96A00	PPP1R14A	O43293	DAPK3	S16	A20T	20	Missense	distal	4	no	8.680	8.643	EPSD	COSMIC	6.449	Down-regulation
CAMK_DAPK_DAPK_DAPK3_ST	Q96A00	PPP1R14A	O43293	DAPK3	S16	P23A	23	Missense	distal	7	no	8.680	8.685	EPSD	COSMIC	6.449	Up-regulation
CAMK_DAPK_DAPK_DAPK3_ST	Q96A00	PPP1R14A	O43293	DAPK3	T38	V39I	39	Missense	proximal	1	no	9.447	9.436	EPSD;PhosphoSitePlus	COSMIC;CCLE	6.449	Down-regulation
CAMK_DAPK_DAPK_DAPK3_ST	Q96A00	PPP1R14A	O43293	DAPK3	T38	D42N	42	Missense	distal	4	no	9.447	9.407	EPSD;PhosphoSitePlus	COSMIC	6.449	Down-regulation
CAMK_DAPK_DAPK_DAPK3_ST	Q96A00	PPP1R14A	O43293	DAPK3	S128	P122L	122	Missense	distal	-6	no	6.517	6.830	EPSD	COSMIC	6.449	Up-regulation
CAMK_DAPK_DAPK_DAPK3_ST	O43293	DAPK3	O43293	DAPK3	S50	R47H	47	Missense	distal	-3	no	10.604	6.072	EPSD	COSMIC	6.449	Loss
CAMK_DAPK_DAPK_DAPK3_ST	O43293	DAPK3	O43293	DAPK3	S50	R54L	54	Missense	distal	4	no	10.604	10.652	EPSD	COSMIC	6.449	Up-regulation
CAMK_DAPK_DAPK_DAPK3_ST	O43293	DAPK3	O43293	DAPK3	S50	R53Q	53	Missense	distal	3	no	10.604	10.757	EPSD	COSMIC	6.449	Up-regulation
CAMK_DAPK_DAPK_DAPK3_ST	O43293	DAPK3	O43293	DAPK3	S50	F43L	43	Missense	distal	-7	no	10.604	11.220	EPSD	COSMIC	6.449	Up-regulation
CAMK_DAPK_DAPK_DAPK3_ST	O43293	DAPK3	O43293	DAPK3	S50	S57T	57	Missense	distal	7	no	10.604	10.643	EPSD	COSMIC	6.449	Up-regulation
CAMK_DAPK_DAPK_DAPK3_ST	O43293	DAPK3	O43293	DAPK3	T180	T180I	180	Missense	central	0	yes	9.757	0.000	EPSD;PhosphoSitePlus	COSMIC	6.449	Loss
CAMK_DAPK_DAPK_DAPK3_ST	O43293	DAPK3	O43293	DAPK3	T180	E173K	173	Missense	distal	-7	no	9.757	10.747	EPSD;PhosphoSitePlus	COSMIC	6.449	Up-regulation
CAMK_DAPK_DAPK_DAPK3_ST	O43293	DAPK3	O43293	DAPK3	T225	T225M	225	Missense	central	0	yes	10.089	0.000	EPSD;PhosphoSitePlus	COSMIC	6.449	Loss
CAMK_DAPK_DAPK_DAPK3_ST	O43293	DAPK3	O43293	DAPK3	T225	V232M	232	Missense	distal	7	no	10.089	10.063	EPSD;PhosphoSitePlus	COSMIC	6.449	Down-regulation
CAMK_DAPK_DAPK_DAPK3_ST	O43293	DAPK3	O43293	DAPK3	T265	E271Q	271	Missense	distal	6	no	12.236	12.217	EPSD;PhosphoSitePlus	COSMIC	6.449	Down-regulation
CAMK_DAPK_DAPK_DAPK3_ST	O43293	DAPK3	O43293	DAPK3	T265	K258N	258	Missense	distal	-7	no	12.236	11.110	EPSD;PhosphoSitePlus	COSMIC	6.449	Down-regulation
CAMK_DAPK_DAPK_DAPK3_ST	O43293	DAPK3	O43293	DAPK3	T299	Y305C	305	Missense	distal	6	no	12.364	12.359	EPSD;PhosphoSitePlus	COSMIC;CCLE	6.449	Down-regulation
CAMK_DAPK_DAPK_DAPK3_ST	O43293	DAPK3	O43293	DAPK3	T299	R296C	296	Missense	distal	-3	no	12.364	6.260	EPSD;PhosphoSitePlus	COSMIC	6.449	Loss
CAMK_DAPK_DAPK_DAPK3_ST	O43293	DAPK3	O43293	DAPK3	T299	T300M	300	Missense	proximal	1	no	12.364	12.376	EPSD;PhosphoSitePlus	COSMIC;CCLE	6.449	Up-regulation
CAMK_DAPK_DAPK_DAPK3_ST	O43293	DAPK3	O43293	DAPK3	T299	R295L	295	Missense	distal	-4	no	12.364	12.001	EPSD;PhosphoSitePlus	COSMIC	6.449	Down-regulation
CAMK_DAPK_DAPK_DAPK3_ST	O43293	DAPK3	O43293	DAPK3	T299	Y305H	305	Missense	distal	6	no	12.364	12.348	EPSD;PhosphoSitePlus	COSMIC	6.449	Down-regulation
CAMK_DAPK_DAPK_DAPK3_ST	O43293	DAPK3	O43293	DAPK3	T306	Y305C	305	Missense	proximal	-1	no	11.911	11.871	PhosphoSitePlus;EPSD	COSMIC;CCLE	6.449	Down-regulation
CAMK_DAPK_DAPK_DAPK3_ST	O43293	DAPK3	O43293	DAPK3	T306	T300M	300	Missense	distal	-6	no	11.911	11.973	PhosphoSitePlus;EPSD	COSMIC;CCLE	6.449	Up-regulation
CAMK_DAPK_DAPK_DAPK3_ST	O43293	DAPK3	O43293	DAPK3	T306	Y305H	305	Missense	proximal	-1	no	11.911	11.815	PhosphoSitePlus;EPSD	COSMIC	6.449	Down-regulation
CAMK_DAPK_DAPK_DAPK3_ST	O43293	DAPK3	O43293	DAPK3	S311	Y305C	305	Missense	distal	-6	no	11.084	10.844	EPSD;PhosphoSitePlus	COSMIC;CCLE	6.449	Down-regulation
CAMK_DAPK_DAPK_DAPK3_ST	O43293	DAPK3	O43293	DAPK3	S311	Y305H	305	Missense	distal	-6	no	11.084	10.552	EPSD;PhosphoSitePlus	COSMIC	6.449	Down-regulation
CAMK_DAPK_DAPK_DAPK3_ST	O43293	DAPK3	O43293	DAPK3	S414	E421K	421	Missense	distal	7	no	6.695	6.550	EPSD	COSMIC	6.449	Down-regulation
CAMK_DAPK_DAPK_DAPK3_ST	O43293	DAPK3	O43293	DAPK3	S414	R419C	419	Missense	distal	5	no	6.695	6.380	EPSD	COSMIC	6.449	Loss
CAMK_DAPK_DAPK_DAPK3_ST	Q00987	MDM2	O43293	DAPK3	T47	G42A	42	Missense	distal	-5	no	6.776	7.618	EPSD	COSMIC	6.449	Up-regulation
CAMK_DAPK_DAPK_DAPK3_ST	Q00987	MDM2	O43293	DAPK3	T47	L54V	54	Missense	distal	7	no	6.776	6.745	EPSD	COSMIC	6.449	Down-regulation
CAMK_DAPK_DAPK_DAPK3_ST	Q00987	MDM2	O43293	DAPK3	T47	S40L	40	Missense	distal	-7	no	6.776	7.375	EPSD	COSMIC	6.449	Up-regulation
CAMK_DAPK_DAPK_DAPK3_ST	Q00987	MDM2	O43293	DAPK3	T47	E52Q	52	Missense	distal	5	no	6.776	6.907	EPSD	COSMIC	6.449	Up-regulation
CAMK_DAPK_DAPK_DAPK3_ST	Q00987	MDM2	O43293	DAPK3	T47	A43E	43	Missense	distal	-4	no	6.776	6.935	EPSD	COSMIC	6.449	Up-regulation
CAMK_DAPK_DAPK_DAPK3_ST	Q00987	MDM2	O43293	DAPK3	T47	G42C	42	Missense	distal	-5	no	6.776	6.547	EPSD	COSMIC	6.449	Down-regulation
CAMK_DAPK_DAPK_DAPK3_ST	Q00987	MDM2	O43293	DAPK3	T47	Q44K	44	Missense	distal	-3	no	6.776	8.193	EPSD	COSMIC	6.449	Up-regulation
CAMK_DAPK_DAPK_DAPK3_ST	Q00987	MDM2	O43293	DAPK3	T47	K45Q	45	Missense	proximal	-2	no	6.776	6.331	EPSD	COSMIC;CCLE	6.449	Loss
CAMK_DAPK_DAPK_DAPK3_ST	Q00987	MDM2	O43293	DAPK3	T158	P156R	156	Missense	proximal	-2	no	6.571	8.394	EPSD	COSMIC	6.449	Up-regulation
CAMK_DAPK_DAPK_DAPK3_ST	Q00987	MDM2	O43293	DAPK3	T158	R155T	155	Missense	distal	-3	no	6.571	1.734	EPSD	COSMIC	6.449	Loss
CAMK_DAPK_DAPK_DAPK3_ST	Q00987	MDM2	O43293	DAPK3	T158	S160F	160	Missense	proximal	2	no	6.571	6.657	EPSD	COSMIC	6.449	Up-regulation
CAMK_DAPK_DAPK_DAPK3_ST	Q00987	MDM2	O43293	DAPK3	T158	H151Y	151	Missense	distal	-7	no	6.571	5.847	EPSD	COSMIC	6.449	Loss
CAMK_DAPK_DAPK_DAPK3_ST	Q00987	MDM2	O43293	DAPK3	T158	P156S	156	Missense	proximal	-2	no	6.571	6.857	EPSD	COSMIC	6.449	Up-regulation
CAMK_DAPK_DAPK_DAPK3_ST	Q00987	MDM2	O43293	DAPK3	T158	S159R	159	Missense	proximal	1	no	6.571	6.555	EPSD	COSMIC	6.449	Down-regulation
CAMK_DAPK_DAPK_DAPK3_ST	Q00987	MDM2	O43293	DAPK3	T158	S159G	159	Missense	proximal	1	no	6.571	6.621	EPSD	COSMIC	6.449	Up-regulation
CAMK_DAPK_DAPK_DAPK3_ST	Q00987	MDM2	O43293	DAPK3	T158	S159N	159	Missense	proximal	1	no	6.571	6.578	EPSD	COSMIC	6.449	Up-regulation
CAMK_DAPK_DAPK_DAPK3_ST	Q00987	MDM2	O43293	DAPK3	T158	R161T	161	Missense	distal	3	no	6.571	6.878	EPSD	COSMIC	6.449	Up-regulation
CAMK_DAPK_DAPK_DAPK3_ST	Q00987	MDM2	O43293	DAPK3	S166	E170D	170	Missense	distal	4	no	13.811	13.805	PhosphoSitePlus;EPSD	COSMIC	6.449	Down-regulation
CAMK_DAPK_DAPK_DAPK3_ST	Q00987	MDM2	O43293	DAPK3	S166	S160F	160	Missense	distal	-6	no	13.811	14.310	PhosphoSitePlus;EPSD	COSMIC	6.449	Up-regulation
CAMK_DAPK_DAPK_DAPK3_ST	Q00987	MDM2	O43293	DAPK3	S166	S159R	159	Missense	distal	-7	no	13.811	15.581	PhosphoSitePlus;EPSD	COSMIC	6.449	Up-regulation
CAMK_DAPK_DAPK_DAPK3_ST	Q00987	MDM2	O43293	DAPK3	S166	S159G	159	Missense	distal	-7	no	13.811	13.560	PhosphoSitePlus;EPSD	COSMIC	6.449	Down-regulation
CAMK_DAPK_DAPK_DAPK3_ST	Q00987	MDM2	O43293	DAPK3	S166	D173Y	173	Missense	distal	7	no	13.811	13.785	PhosphoSitePlus;EPSD	COSMIC	6.449	Down-regulation
CAMK_DAPK_DAPK_DAPK3_ST	Q00987	MDM2	O43293	DAPK3	S166	S166C	166	Missense	central	0	yes	13.811	0.000	PhosphoSitePlus;EPSD	COSMIC	6.449	Loss
CAMK_DAPK_DAPK_DAPK3_ST	Q00987	MDM2	O43293	DAPK3	S166	E167Q	167	Missense	proximal	1	no	13.811	13.828	PhosphoSitePlus;EPSD	COSMIC	6.449	Up-regulation
CAMK_DAPK_DAPK_DAPK3_ST	Q00987	MDM2	O43293	DAPK3	S166	S159N	159	Missense	distal	-7	no	13.811	14.709	PhosphoSitePlus;EPSD	COSMIC	6.449	Up-regulation
CAMK_DAPK_DAPK_DAPK3_ST	Q00987	MDM2	O43293	DAPK3	S166	R161T	161	Missense	distal	-5	no	13.811	11.560	PhosphoSitePlus;EPSD	COSMIC	6.449	Down-regulation
CAMK_DAPK_DAPK_DAPK3_ST	Q00987	MDM2	O43293	DAPK3	S166	S166F	166	Missense	central	0	yes	13.811	0.000	PhosphoSitePlus;EPSD	COSMIC	6.449	Loss
CAMK_DAPK_DAPK_DAPK3_ST	Q00987	MDM2	O43293	DAPK3	S186	R183H	183	Missense	distal	-3	no	11.436	6.904	EPSD;PhosphoSitePlus	COSMIC	6.449	Down-regulation
CAMK_DAPK_DAPK_DAPK3_ST	Q00987	MDM2	O43293	DAPK3	S186	I189V	189	Missense	distal	3	no	11.436	11.780	EPSD;PhosphoSitePlus	COSMIC	6.449	Up-regulation
CAMK_DAPK_DAPK_DAPK3_ST	Q00987	MDM2	O43293	DAPK3	S186	K185R	185	Missense	proximal	-1	no	11.436	11.315	EPSD;PhosphoSitePlus	COSMIC	6.449	Down-regulation
CAMK_DAPK_DAPK_DAPK3_ST	Q00987	MDM2	O43293	DAPK3	S186	S190F	190	Missense	distal	4	no	11.436	11.496	EPSD;PhosphoSitePlus	COSMIC	6.449	Up-regulation
CAMK_DAPK_DAPK_DAPK3_ST	Q00987	MDM2	O43293	DAPK3	S186	R183C	183	Missense	distal	-3	no	11.436	5.332	EPSD;PhosphoSitePlus	COSMIC	6.449	Loss
CAMK_DAPK_DAPK_DAPK3_ST	Q00987	MDM2	O43293	DAPK3	S186	R179P	179	Missense	distal	-7	no	11.436	10.663	EPSD;PhosphoSitePlus	COSMIC	6.449	Down-regulation
CAMK_DAPK_DAPK_DAPK3_ST	Q00987	MDM2	O43293	DAPK3	S188	K185R	185	Missense	distal	-3	no	5.268	7.983	EPSD	COSMIC	6.449	Gain
CAMK_DAPK_DAPK_DAPK3_ST	Q00987	MDM2	O43293	DAPK3	S190	K185R	185	Missense	distal	-5	no	5.625	6.456	EPSD	COSMIC	6.449	Gain
CAMK_DAPK_DAPK_DAPK3_ST	Q00987	MDM2	O43293	DAPK3	T351	G356S	356	Missense	distal	5	no	6.716	7.136	EPSD	COSMIC	6.449	Up-regulation
CAMK_DAPK_DAPK_DAPK3_ST	Q00987	MDM2	O43293	DAPK3	T351	E355Q	355	Missense	distal	4	no	6.716	6.683	EPSD	COSMIC	6.449	Down-regulation
CAMK_DAPK_DAPK_DAPK3_ST	Q00987	MDM2	O43293	DAPK3	T351	E354K	354	Missense	distal	3	no	6.716	7.437	EPSD	COSMIC	6.449	Up-regulation
CAMK_DAPK_DAPK_DAPK3_ST	Q00987	MDM2	O43293	DAPK3	T351	E355K	355	Missense	distal	4	no	6.716	6.691	EPSD	COSMIC	6.449	Down-regulation
CAMK_DAPK_DAPK_DAPK3_ST	Q00987	MDM2	O43293	DAPK3	T419	E413K	413	Missense	distal	-6	no	7.625	7.090	EPSD	COSMIC	6.449	Down-regulation
CAMK_DAPK_DAPK_DAPK3_ST	Q00987	MDM2	O43293	DAPK3	T419	E413G	413	Missense	distal	-6	no	7.625	8.183	EPSD	COSMIC	6.449	Up-regulation
CAMK_DAPK_DAPK_DAPK3_ST	Q00987	MDM2	O43293	DAPK3	T419	E415Q	415	Missense	distal	-4	no	7.625	7.601	EPSD	COSMIC	6.449	Down-regulation
CAMK_DAPK_DAPK_DAPK3_ST	Q00987	MDM2	O43293	DAPK3	T419	T419I	419	Missense	central	0	yes	7.625	0.000	EPSD	COSMIC	6.449	Loss
CAMK_DAPK_DAPK_DAPK3_ST	Q00987	MDM2	O43293	DAPK3	T419	S425C	425	Missense	distal	6	no	7.625	7.638	EPSD	COSMIC	6.449	Up-regulation
CAMK_DAPK_DAPK_DAPK3_ST	Q00987	MDM2	O43293	DAPK3	T419	F414I	414	Missense	distal	-5	no	7.625	8.536	EPSD	COSMIC	6.449	Up-regulation
CAMK_DAPK_DAPK_DAPK3_ST	Q00987	MDM2	O43293	DAPK3	T419	V426A	426	Missense	distal	7	no	7.625	7.586	EPSD	COSMIC	6.449	Down-regulation
CAMK_DAPK_DAPK_DAPK3_ST	P40429	RPL13A	O43293	DAPK3	T64	R61Q	61	Missense	distal	-3	no	9.982	5.851	EPSD	COSMIC	6.449	Loss
CAMK_DAPK_DAPK_DAPK3_ST	P40429	RPL13A	O43293	DAPK3	T64	P66L	66	Missense	proximal	2	no	9.982	10.022	EPSD	COSMIC	6.449	Up-regulation
CAMK_DAPK_DAPK_DAPK3_ST	P40429	RPL13A	O43293	DAPK3	T64	T64I	64	Missense	central	0	yes	9.982	0.000	EPSD	COSMIC	6.449	Loss
CAMK_DAPK_DAPK_DAPK3_ST	P40429	RPL13A	O43293	DAPK3	T64	T64N	64	Missense	central	0	yes	9.982	0.000	EPSD	COSMIC	6.449	Loss
CAMK_DAPK_DAPK_DAPK3_ST	O14950	MYL12B	O43293	DAPK3	T19	M25L	25	Missense	distal	6	no	10.367	10.377	EPSD;PhosphoSitePlus	COSMIC	6.449	Up-regulation
CAMK_DAPK_DAPK_DAPK3_ST	O14950	MYL12B	O43293	DAPK3	T19	K12N	12	Missense	distal	-7	no	10.367	9.241	EPSD;PhosphoSitePlus	COSMIC	6.449	Down-regulation
CAMK_DAPK_DAPK_DAPK3_ST	O14950	MYL12B	O43293	DAPK3	S20	M25L	25	Missense	distal	5	no	11.851	11.830	PhosphoSitePlus;EPSD	COSMIC	6.449	Down-regulation
CAMK_DAPK_DAPK_DAPK3_ST	P04637	TP53	O43293	DAPK3	S20	T18R	18	Missense	proximal	-2	no	4.971	6.908	PhosphoSitePlus	COSMIC	6.449	Gain
CAMK_DAPK_DAPK_DAPK3_ST	P04637	TP53	O43293	DAPK3	S149	W146R	146	Missense	distal	-3	no	2.414	8.306	EPSD	COSMIC	6.449	Gain
CAMK_DAPK_DAPK_DAPK3_ST	P04637	TP53	O43293	DAPK3	S215	R209G	209	Missense	distal	-6	no	5.367	6.560	EPSD	COSMIC	6.449	Gain
CAMK_DAPK_DAPK_DAPK3_ST	P04637	TP53	O43293	DAPK3	S215	R209C	209	Missense	distal	-6	no	5.367	6.459	EPSD	COSMIC	6.449	Gain
CAMK_DAPK_DAPK_DAPK3_ST	P04637	TP53	O43293	DAPK3	S215	D208E	208	Missense	distal	-7	no	5.367	6.975	EPSD	COSMIC	6.449	Gain
CAMK_DAPK_DAPK_DAPK3_ST	P04637	TP53	O43293	DAPK3	S215	F212I	212	Missense	distal	-3	no	5.367	6.595	EPSD	COSMIC	6.449	Gain
CAMK_DAPK_DAPK_DAPK3_ST	P04637	TP53	O43293	DAPK3	S215	N210K	210	Missense	distal	-5	no	5.367	6.783	EPSD	COSMIC	6.449	Gain
CAMK_DAPK_DAPK_DAPK3_ST	P04637	TP53	O43293	DAPK3	S215	F212S	212	Missense	distal	-3	no	5.367	6.730	EPSD	COSMIC	6.449	Gain
CAMK_DAPK_DAPK_DAPK3_ST	P04637	TP53	O43293	DAPK3	T284	D281R	281	Missense	distal	-3	no	1.913	9.058	EPSD	COSMIC	6.449	Gain
CAMK_DAPK_DAPK_DAPK3_ST	P04637	TP53	O43293	DAPK3	T312	P309R	309	Missense	distal	-3	no	4.446	8.775	EPSD	COSMIC	6.449	Gain
CAMK_DAPK_DAPK_DAPK3_ST	P04637	TP53	O43293	DAPK3	S362	S367F	367	Missense	distal	5	no	7.685	7.347	EPSD	COSMIC	6.449	Down-regulation
CAMK_DAPK_DAPK_DAPK3_ST	P04637	TP53	O43293	DAPK3	S362	G361E	361	Missense	proximal	-1	no	7.685	7.647	EPSD	COSMIC	6.449	Down-regulation
CAMK_DAPK_DAPK_DAPK3_ST	P04637	TP53	O43293	DAPK3	S362	E358V	358	Missense	distal	-4	no	7.685	7.325	EPSD	COSMIC	6.449	Down-regulation
CAMK_DAPK_DAPK_DAPK3_ST	P04637	TP53	O43293	DAPK3	S362	P359S	359	Missense	distal	-3	no	7.685	7.381	EPSD	COSMIC	6.449	Down-regulation
CAMK_DAPK_DAPK_DAPK3_ST	P04637	TP53	O43293	DAPK3	S362	A364D	364	Missense	proximal	2	no	7.685	7.761	EPSD	COSMIC	6.449	Up-regulation
CAMK_DAPK_DAPK_DAPK3_ST	P04637	TP53	O43293	DAPK3	S362	H365Y	365	Missense	distal	3	no	7.685	7.703	EPSD	COSMIC	6.449	Up-regulation
CAMK_DAPK_DAPK_DAPK3_ST	P04637	TP53	O43293	DAPK3	S362	G360A	360	Missense	proximal	-2	no	7.685	8.346	EPSD	COSMIC	6.449	Up-regulation
CAMK_DAPK_DAPK_DAPK3_ST	P04637	TP53	O43293	DAPK3	S362	A364T	364	Missense	proximal	2	no	7.685	7.692	EPSD	COSMIC	6.449	Up-regulation
CAMK_DAPK_DAPK_DAPK3_ST	P04637	TP53	O43293	DAPK3	S362	G356W	356	Missense	distal	-6	no	7.685	7.501	EPSD	COSMIC	6.449	Down-regulation
CAMK_DAPK_DAPK_DAPK3_ST	P04637	TP53	O43293	DAPK3	S362	S366A	366	Missense	distal	4	no	7.685	7.672	EPSD	COSMIC	6.449	Down-regulation
CAMK_DAPK_DAPK_DAPK3_ST	P04637	TP53	O43293	DAPK3	S362	E358Q	358	Missense	distal	-4	no	7.685	7.661	EPSD	COSMIC	6.449	Down-regulation
CAMK_DAPK_DAPK_DAPK3_ST	P04637	TP53	O43293	DAPK3	S362	G361R	361	Missense	proximal	-1	no	7.685	7.452	EPSD	COSMIC	6.449	Down-regulation
CAMK_DAPK_DAPK_DAPK3_ST	P04637	TP53	O43293	DAPK3	S362	E358K	358	Missense	distal	-4	no	7.685	7.862	EPSD	COSMIC	6.449	Up-regulation
CAMK_DAPK_DAPK_DAPK3_ST	P04637	TP53	O43293	DAPK3	S366	S367F	367	Missense	proximal	1	no	8.392	8.437	EPSD	COSMIC	6.449	Up-regulation
CAMK_DAPK_DAPK_DAPK3_ST	P04637	TP53	O43293	DAPK3	S366	K370N	370	Missense	distal	4	no	8.392	8.370	EPSD	COSMIC	6.449	Down-regulation
CAMK_DAPK_DAPK_DAPK3_ST	P04637	TP53	O43293	DAPK3	S366	G361E	361	Missense	distal	-5	no	8.392	9.123	EPSD	COSMIC	6.449	Up-regulation
CAMK_DAPK_DAPK_DAPK3_ST	P04637	TP53	O43293	DAPK3	S366	P359S	359	Missense	distal	-7	no	8.392	7.396	EPSD	COSMIC	6.449	Down-regulation
CAMK_DAPK_DAPK_DAPK3_ST	P04637	TP53	O43293	DAPK3	S366	A364D	364	Missense	proximal	-2	no	8.392	6.902	EPSD	COSMIC	6.449	Down-regulation
CAMK_DAPK_DAPK_DAPK3_ST	P04637	TP53	O43293	DAPK3	S366	H365Y	365	Missense	proximal	-1	no	8.392	8.487	EPSD	COSMIC	6.449	Up-regulation
CAMK_DAPK_DAPK_DAPK3_ST	P04637	TP53	O43293	DAPK3	S366	G360A	360	Missense	distal	-6	no	8.392	7.854	EPSD	COSMIC	6.449	Down-regulation
CAMK_DAPK_DAPK_DAPK3_ST	P04637	TP53	O43293	DAPK3	S366	A364T	364	Missense	proximal	-2	no	8.392	7.882	EPSD	COSMIC	6.449	Down-regulation
CAMK_DAPK_DAPK_DAPK3_ST	P04637	TP53	O43293	DAPK3	S366	S366A	366	Missense	central	0	yes	8.392	0.000	EPSD	COSMIC	6.449	Loss
CAMK_DAPK_DAPK_DAPK3_ST	P04637	TP53	O43293	DAPK3	S366	G361R	361	Missense	distal	-5	no	8.392	10.952	EPSD	COSMIC	6.449	Up-regulation
CAMK_DAPK_DAPK_DAPK3_ST	P04637	TP53	O43293	DAPK3	S366	K370Q	370	Missense	distal	4	no	8.392	8.384	EPSD	COSMIC	6.449	Down-regulation
CAMK_DAPK_DAPK_DAPK3_ST	P04637	TP53	O43293	DAPK3	S366	K373R	373	Missense	distal	7	no	8.392	8.479	EPSD	COSMIC	6.449	Up-regulation
CAMK_DAPK_DAPK_DAPK3_ST	P04637	TP53	O43293	DAPK3	S366	S371P	371	Missense	distal	5	no	8.392	8.201	EPSD	COSMIC	6.449	Down-regulation
CAMK_DAPK_DAPK_DAPK3_ST	P38936	CDKN1A	O43293	DAPK3	S31	R32C	32	Missense	proximal	1	no	6.680	6.733	EPSD	COSMIC	6.449	Up-regulation
CAMK_DAPK_DAPK_DAPK3_ST	P38936	CDKN1A	O43293	DAPK3	S31	P24S	24	Missense	distal	-7	no	6.680	5.683	EPSD	COSMIC	6.449	Loss
CAMK_DAPK_DAPK_DAPK3_ST	P38936	CDKN1A	O43293	DAPK3	S31	S27T	27	Missense	distal	-4	no	6.680	6.800	EPSD	COSMIC	6.449	Up-regulation
CAMK_DAPK_DAPK_DAPK3_ST	P38936	CDKN1A	O43293	DAPK3	T97	G90R	90	Missense	distal	-7	no	11.362	13.382	EPSD	COSMIC	6.449	Up-regulation
CAMK_DAPK_DAPK_DAPK3_ST	P38936	CDKN1A	O43293	DAPK3	T97	T97I	97	Missense	central	0	yes	11.362	0.000	EPSD	COSMIC	6.449	Loss
CAMK_DAPK_DAPK_DAPK3_ST	P38936	CDKN1A	O43293	DAPK3	S98	T97I	97	Missense	proximal	-1	no	6.600	6.778	EPSD	COSMIC	6.449	Up-regulation
CAMK_DAPK_DAPK_DAPK3_ST	P38936	CDKN1A	O43293	DAPK3	T145	D149N	149	Missense	distal	4	no	14.198	14.157	PhosphoSitePlus	COSMIC	6.449	Down-regulation
CAMK_DAPK_DAPK_DAPK3_ST	P38936	CDKN1A	O43293	DAPK3	T145	R143W	143	Missense	proximal	-2	no	14.198	11.878	PhosphoSitePlus	COSMIC;GDSC;CCLE	6.449	Down-regulation
CAMK_DAPK_DAPK_DAPK3_ST	P38936	CDKN1A	O43293	DAPK3	T145	Q138E	138	Missense	distal	-7	no	14.198	14.245	PhosphoSitePlus	COSMIC	6.449	Up-regulation
CAMK_DAPK_DAPK_DAPK3_ST	P38936	CDKN1A	O43293	DAPK3	T145	G139C	139	Missense	distal	-6	no	14.198	14.097	PhosphoSitePlus	COSMIC	6.449	Down-regulation
CAMK_DAPK_DAPK_DAPK3_ST	P38936	CDKN1A	O43293	DAPK3	S146	T145S	145	Missense	proximal	-1	no	6.558	6.635	EPSD	COSMIC	6.449	Up-regulation
CAMK_DAPK_DAPK_DAPK3_ST	P38936	CDKN1A	O43293	DAPK3	S146	D149N	149	Missense	distal	3	no	6.558	7.198	EPSD	COSMIC	6.449	Up-regulation
CAMK_DAPK_DAPK_DAPK3_ST	P38936	CDKN1A	O43293	DAPK3	S146	R143W	143	Missense	distal	-3	no	6.558	0.666	EPSD	COSMIC;GDSC;CCLE	6.449	Loss
CAMK_DAPK_DAPK_DAPK3_ST	P38936	CDKN1A	O43293	DAPK3	S146	G139C	139	Missense	distal	-7	no	6.558	6.652	EPSD	COSMIC	6.449	Up-regulation
TK_FGFR_FGFR2_Y	P21802	FGFR2	P21802	FGFR2	Y466	G462V	462	Missense	distal	-4	no	2.991	2.760	EPSD	COSMIC	1.189	Down-regulation
TK_FGFR_FGFR2_Y	P21802	FGFR2	P21802	FGFR2	Y466	E470Q	470	Missense	distal	4	no	2.991	2.969	EPSD	COSMIC	1.189	Down-regulation
TK_FGFR_FGFR2_Y	P21802	FGFR2	P21802	FGFR2	Y466	V463I	463	Missense	distal	-3	no	2.991	3.014	EPSD	COSMIC	1.189	Up-regulation
TK_FGFR_FGFR2_Y	P21802	FGFR2	P21802	FGFR2	Y466	P469S	469	Missense	distal	3	no	2.991	3.008	EPSD	COSMIC	1.189	Up-regulation
TK_FGFR_FGFR2_Y	P21802	FGFR2	P21802	FGFR2	Y466	E470D	470	Missense	distal	4	no	2.991	2.998	EPSD	COSMIC	1.189	Up-regulation
TK_FGFR_FGFR2_Y	P21802	FGFR2	P21802	FGFR2	Y466	D471Y	471	Missense	distal	5	no	2.991	2.706	EPSD	COSMIC	1.189	Down-regulation
TK_FGFR_FGFR2_Y	P21802	FGFR2	P21802	FGFR2	Y466	D471N	471	Missense	distal	5	no	2.991	3.202	EPSD	COSMIC	1.189	Up-regulation
TK_FGFR_FGFR2_Y	P21802	FGFR2	P21802	FGFR2	Y466	V463D	463	Missense	distal	-3	no	2.991	2.966	EPSD	COSMIC	1.189	Down-regulation
TK_FGFR_FGFR2_Y	P21802	FGFR2	P21802	FGFR2	Y466	L460V	460	Missense	distal	-6	no	2.991	3.205	EPSD	COSMIC	1.189	Up-regulation
TK_FGFR_FGFR2_Y	P21802	FGFR2	P21802	FGFR2	Y466	G462A	462	Missense	distal	-4	no	2.991	2.851	EPSD	COSMIC	1.189	Down-regulation
TK_FGFR_FGFR2_Y	P21802	FGFR2	P21802	FGFR2	Y466	A461V	461	Missense	distal	-5	no	2.991	2.980	EPSD	COSMIC	1.189	Down-regulation
TK_FGFR_FGFR2_Y	P21802	FGFR2	P21802	FGFR2	Y466	A461S	461	Missense	distal	-5	no	2.991	3.001	EPSD	COSMIC	1.189	Up-regulation
TK_FGFR_FGFR2_Y	P21802	FGFR2	P21802	FGFR2	Y466	E467K	467	Missense	proximal	1	no	2.991	3.011	EPSD	COSMIC	1.189	Up-regulation
TK_FGFR_FGFR2_Y	P21802	FGFR2	P21802	FGFR2	Y466	G462W	462	Missense	distal	-4	no	2.991	2.792	EPSD	COSMIC	1.189	Down-regulation
TK_FGFR_FGFR2_Y	P21802	FGFR2	P21802	FGFR2	Y466	G462R	462	Missense	distal	-4	no	2.991	2.717	EPSD	COSMIC	1.189	Down-regulation
TK_FGFR_FGFR2_Y	P21802	FGFR2	P21802	FGFR2	Y466	P469Q	469	Missense	distal	3	no	2.991	2.927	EPSD	COSMIC	1.189	Down-regulation
TK_FGFR_FGFR2_Y	P21802	FGFR2	P21802	FGFR2	Y586	V593M	593	Missense	distal	7	no	3.301	3.297	EPSD	COSMIC	1.189	Down-regulation
TK_FGFR_FGFR2_Y	P21802	FGFR2	P21802	FGFR2	Y586	M584R	584	Missense	proximal	-2	no	3.301	3.300	EPSD	COSMIC;CCLE	1.189	Down-regulation
TK_FGFR_FGFR2_Y	P21802	FGFR2	P21802	FGFR2	Y586	P581Q	581	Missense	distal	-5	no	3.301	3.297	EPSD	COSMIC	1.189	Down-regulation
TK_FGFR_FGFR2_Y	P21802	FGFR2	P21802	FGFR2	Y586	N591Y	591	Missense	distal	5	no	3.301	2.805	EPSD	COSMIC	1.189	Down-regulation
TK_FGFR_FGFR2_Y	P21802	FGFR2	P21802	FGFR2	Y586	S587C	587	Missense	proximal	1	no	3.301	3.315	EPSD	COSMIC	1.189	Up-regulation
TK_FGFR_FGFR2_Y	P21802	FGFR2	P21802	FGFR2	Y586	R592C	592	Missense	distal	6	no	3.301	3.232	EPSD	COSMIC	1.189	Down-regulation
TK_FGFR_FGFR2_Y	P21802	FGFR2	P21802	FGFR2	Y586	D589G	589	Missense	distal	3	no	3.301	3.009	EPSD	COSMIC	1.189	Down-regulation
TK_FGFR_FGFR2_Y	P21802	FGFR2	P21802	FGFR2	Y586	P582L	582	Missense	distal	-4	no	3.301	3.012	EPSD	COSMIC;CCLE	1.189	Down-regulation
TK_FGFR_FGFR2_Y	P21802	FGFR2	P21802	FGFR2	Y586	R592G	592	Missense	distal	6	no	3.301	3.683	EPSD	COSMIC	1.189	Up-regulation
TK_FGFR_FGFR2_Y	P21802	FGFR2	P21802	FGFR2	Y586	G583R	583	Missense	distal	-3	no	3.301	3.324	EPSD	COSMIC	1.189	Up-regulation
TK_FGFR_FGFR2_Y	P21802	FGFR2	P21802	FGFR2	Y586	G583V	583	Missense	distal	-3	no	3.301	3.334	EPSD	COSMIC	1.189	Up-regulation
TK_FGFR_FGFR2_Y	P21802	FGFR2	P21802	FGFR2	Y586	I590M	590	Missense	distal	4	no	3.301	3.278	EPSD	COSMIC	1.189	Down-regulation
TK_FGFR_FGFR2_Y	P21802	FGFR2	P21802	FGFR2	Y586	E585G	585	Missense	proximal	-1	no	3.301	3.168	EPSD	COSMIC	1.189	Down-regulation
TK_FGFR_FGFR2_Y	P21802	FGFR2	P21802	FGFR2	Y586	D589Y	589	Missense	distal	3	no	3.301	3.186	EPSD	COSMIC	1.189	Down-regulation
TK_FGFR_FGFR2_Y	P21802	FGFR2	P21802	FGFR2	Y588	E595K	595	Missense	distal	7	no	3.238	3.237	EPSD	COSMIC	1.189	Down-regulation
TK_FGFR_FGFR2_Y	P21802	FGFR2	P21802	FGFR2	Y588	V593M	593	Missense	distal	5	no	3.238	3.099	EPSD	COSMIC	1.189	Down-regulation
TK_FGFR_FGFR2_Y	P21802	FGFR2	P21802	FGFR2	Y588	M584R	584	Missense	distal	-4	no	3.238	3.080	EPSD	COSMIC;CCLE	1.189	Down-regulation
TK_FGFR_FGFR2_Y	P21802	FGFR2	P21802	FGFR2	Y588	P594H	594	Missense	distal	6	no	3.238	2.672	EPSD	COSMIC	1.189	Down-regulation
TK_FGFR_FGFR2_Y	P21802	FGFR2	P21802	FGFR2	Y588	P581Q	581	Missense	distal	-7	no	3.238	3.229	EPSD	COSMIC	1.189	Down-regulation
TK_FGFR_FGFR2_Y	P21802	FGFR2	P21802	FGFR2	Y588	N591Y	591	Missense	distal	3	no	3.238	3.364	EPSD	COSMIC	1.189	Up-regulation
TK_FGFR_FGFR2_Y	P21802	FGFR2	P21802	FGFR2	Y588	S587C	587	Missense	proximal	-1	no	3.238	3.112	EPSD	COSMIC	1.189	Down-regulation
TK_FGFR_FGFR2_Y	P21802	FGFR2	P21802	FGFR2	Y588	R592C	592	Missense	distal	4	no	3.238	3.233	EPSD	COSMIC	1.189	Down-regulation
TK_FGFR_FGFR2_Y	P21802	FGFR2	P21802	FGFR2	Y588	D589G	589	Missense	proximal	1	no	3.238	3.237	EPSD	COSMIC	1.189	Down-regulation
TK_FGFR_FGFR2_Y	P21802	FGFR2	P21802	FGFR2	Y588	P582L	582	Missense	distal	-6	no	3.238	3.353	EPSD	COSMIC;CCLE	1.189	Up-regulation
TK_FGFR_FGFR2_Y	P21802	FGFR2	P21802	FGFR2	Y588	G583R	583	Missense	distal	-5	no	3.238	3.244	EPSD	COSMIC	1.189	Up-regulation
TK_FGFR_FGFR2_Y	P21802	FGFR2	P21802	FGFR2	Y588	G583V	583	Missense	distal	-5	no	3.238	3.216	EPSD	COSMIC	1.189	Down-regulation
TK_FGFR_FGFR2_Y	P21802	FGFR2	P21802	FGFR2	Y588	I590M	590	Missense	proximal	2	no	3.238	3.180	EPSD	COSMIC	1.189	Down-regulation
TK_FGFR_FGFR2_Y	P21802	FGFR2	P21802	FGFR2	Y588	P594L	594	Missense	distal	6	no	3.238	2.843	EPSD	COSMIC	1.189	Down-regulation
TK_FGFR_FGFR2_Y	P21802	FGFR2	P21802	FGFR2	Y588	P594S	594	Missense	distal	6	no	3.238	2.574	EPSD	COSMIC	1.189	Down-regulation
TK_FGFR_FGFR2_Y	P21802	FGFR2	P21802	FGFR2	Y588	E585G	585	Missense	distal	-3	no	3.238	3.242	EPSD	COSMIC	1.189	Up-regulation
TK_FGFR_FGFR2_Y	P21802	FGFR2	P21802	FGFR2	Y588	D589Y	589	Missense	proximal	1	no	3.238	3.239	EPSD	COSMIC	1.189	Up-regulation
TK_FGFR_FGFR2_Y	P21802	FGFR2	P21802	FGFR2	Y656	D655N	655	Missense	proximal	-1	no	3.779	3.742	EPSD	COSMIC	1.189	Down-regulation
TK_FGFR_FGFR2_Y	P21802	FGFR2	P21802	FGFR2	Y656	K659E	659	Missense	distal	3	no	3.779	3.369	EPSD	COSMIC;CCLE	1.189	Down-regulation
TK_FGFR_FGFR2_Y	P21802	FGFR2	P21802	FGFR2	Y656	K659N	659	Missense	distal	3	no	3.779	3.551	EPSD	COSMIC	1.189	Down-regulation
TK_FGFR_FGFR2_Y	P21802	FGFR2	P21802	FGFR2	Y656	K659M	659	Missense	distal	3	no	3.779	3.555	EPSD	COSMIC	1.189	Down-regulation
TK_FGFR_FGFR2_Y	P21802	FGFR2	P21802	FGFR2	Y656	D650H	650	Missense	distal	-6	no	3.779	3.270	EPSD	COSMIC	1.189	Down-regulation
TK_FGFR_FGFR2_Y	P21802	FGFR2	P21802	FGFR2	Y656	D655G	655	Missense	proximal	-1	no	3.779	3.620	EPSD	COSMIC	1.189	Down-regulation
TK_FGFR_FGFR2_Y	P21802	FGFR2	P21802	FGFR2	Y656	K659R	659	Missense	distal	3	no	3.779	3.655	EPSD	COSMIC	1.189	Down-regulation
TK_FGFR_FGFR2_Y	P21802	FGFR2	P21802	FGFR2	Y656	I654T	654	Missense	proximal	-2	no	3.779	3.778	EPSD	COSMIC	1.189	Down-regulation
TK_FGFR_FGFR2_Y	P21802	FGFR2	P21802	FGFR2	Y656	D650Y	650	Missense	distal	-6	no	3.779	3.481	EPSD	COSMIC	1.189	Down-regulation
TK_FGFR_FGFR2_Y	P21802	FGFR2	P21802	FGFR2	Y656	N652S	652	Missense	distal	-4	no	3.779	3.512	EPSD	COSMIC	1.189	Down-regulation
TK_FGFR_FGFR2_Y	P21802	FGFR2	P21802	FGFR2	Y656	R649S	649	Missense	distal	-7	no	3.779	3.680	EPSD	COSMIC	1.189	Down-regulation
TK_FGFR_FGFR2_Y	P21802	FGFR2	P21802	FGFR2	Y656	R649G	649	Missense	distal	-7	no	3.779	3.700	EPSD	COSMIC	1.189	Down-regulation
TK_FGFR_FGFR2_Y	P21802	FGFR2	P21802	FGFR2	Y656	R649M	649	Missense	distal	-7	no	3.779	3.750	EPSD	COSMIC	1.189	Down-regulation
TK_FGFR_FGFR2_Y	P21802	FGFR2	P21802	FGFR2	Y657	K659E	659	Missense	proximal	2	no	3.400	3.272	EPSD	COSMIC;CCLE	1.189	Down-regulation
TK_FGFR_FGFR2_Y	P21802	FGFR2	P21802	FGFR2	Y657	K659N	659	Missense	proximal	2	no	3.400	3.338	EPSD	COSMIC	1.189	Down-regulation
TK_FGFR_FGFR2_Y	P21802	FGFR2	P21802	FGFR2	Y657	R664W	664	Missense	distal	7	no	3.400	3.403	EPSD	COSMIC	1.189	Up-regulation
TK_FGFR_FGFR2_Y	P21802	FGFR2	P21802	FGFR2	Y657	K659M	659	Missense	proximal	2	no	3.400	3.341	EPSD	COSMIC	1.189	Down-regulation
TK_FGFR_FGFR2_Y	P21802	FGFR2	P21802	FGFR2	Y657	D650H	650	Missense	distal	-7	no	3.400	3.345	EPSD	COSMIC	1.189	Down-regulation
TK_FGFR_FGFR2_Y	P21802	FGFR2	P21802	FGFR2	Y657	D655G	655	Missense	proximal	-2	no	3.400	3.398	EPSD	COSMIC	1.189	Down-regulation
TK_FGFR_FGFR2_Y	P21802	FGFR2	P21802	FGFR2	Y657	K659R	659	Missense	proximal	2	no	3.400	3.363	EPSD	COSMIC	1.189	Down-regulation
TK_FGFR_FGFR2_Y	P21802	FGFR2	P21802	FGFR2	Y657	I654T	654	Missense	distal	-3	no	3.400	3.325	EPSD	COSMIC	1.189	Down-regulation
TK_FGFR_FGFR2_Y	P21802	FGFR2	P21802	FGFR2	Y657	D650Y	650	Missense	distal	-7	no	3.400	3.374	EPSD	COSMIC	1.189	Down-regulation
TK_FGFR_FGFR2_Y	P21802	FGFR2	P21802	FGFR2	Y657	N652S	652	Missense	distal	-5	no	3.400	3.441	EPSD	COSMIC	1.189	Up-regulation
TK_FGFR_FGFR2_Y	P21802	FGFR2	P21802	FGFR2	Y769	L770V	770	Missense	proximal	1	no	2.917	2.916	PhosphoSitePlus	COSMIC	1.189	Down-regulation
TK_FGFR_FGFR2_Y	P21802	FGFR2	P21802	FGFR2	Y769	L772F	772	Missense	distal	3	no	2.917	3.032	PhosphoSitePlus	COSMIC	1.189	Up-regulation
TK_FGFR_FGFR2_Y	P21802	FGFR2	P21802	FGFR2	Y769	E767K	767	Missense	proximal	-2	no	2.917	2.913	PhosphoSitePlus	COSMIC	1.189	Down-regulation
TK_FGFR_FGFR2_Y	P21802	FGFR2	P21802	FGFR2	Y769	S773N	773	Missense	distal	4	no	2.917	2.905	PhosphoSitePlus	COSMIC	1.189	Down-regulation
TK_FGFR_FGFR2_Y	P21802	FGFR2	P21802	FGFR2	Y769	D771N	771	Missense	proximal	2	no	2.917	2.870	PhosphoSitePlus	COSMIC	1.189	Down-regulation
TK_FGFR_FGFR2_Y	P21802	FGFR2	P21802	FGFR2	Y769	L763V	763	Missense	distal	-6	no	2.917	3.131	PhosphoSitePlus	COSMIC	1.189	Up-regulation
TK_FGFR_FGFR2_Y	P21802	FGFR2	P21802	FGFR2	Y769	P775S	775	Missense	distal	6	no	2.917	2.253	PhosphoSitePlus	COSMIC	1.189	Down-regulation
TK_FGFR_FGFR2_Y	P21802	FGFR2	P21802	FGFR2	Y769	L770F	770	Missense	proximal	1	no	2.917	2.922	PhosphoSitePlus	COSMIC	1.189	Up-regulation
TK_FGFR_FGFR2_Y	P35222	CTNNB1	P21802	FGFR2	Y30	I35N	35	Missense	distal	5	no	0.494	1.224	EPSD	COSMIC	1.189	Gain
TK_FGFR_FGFR2_Y	P35222	CTNNB1	P21802	FGFR2	Y64	G69E	69	Missense	distal	5	no	0.667	1.400	EPSD	COSMIC	1.189	Gain
TK_FGFR_FGFR2_Y	P35222	CTNNB1	P21802	FGFR2	Y142	D144N	144	Missense	proximal	2	no	3.637	3.590	PhosphoSitePlus	COSMIC	1.189	Down-regulation
TK_FGFR_FGFR2_Y	P35222	CTNNB1	P21802	FGFR2	Y142	E147K	147	Missense	distal	5	no	3.637	2.894	PhosphoSitePlus	COSMIC	1.189	Down-regulation
TK_FGFR_FGFR2_Y	P35222	CTNNB1	P21802	FGFR2	Y142	A149V	149	Missense	distal	7	no	3.637	3.620	PhosphoSitePlus	COSMIC	1.189	Down-regulation
TK_FGFR_FGFR2_Y	P35222	CTNNB1	P21802	FGFR2	Y142	A149T	149	Missense	distal	7	no	3.637	3.631	PhosphoSitePlus	COSMIC	1.189	Down-regulation
TK_FGFR_FGFR2_Y	P35222	CTNNB1	P21802	FGFR2	Y142	I140T	140	Missense	proximal	-2	no	3.637	3.636	PhosphoSitePlus	COSMIC	1.189	Down-regulation
TK_FGFR_FGFR2_Y	P35222	CTNNB1	P21802	FGFR2	Y142	A146T	146	Missense	distal	4	no	3.637	3.661	PhosphoSitePlus	COSMIC	1.189	Up-regulation
TK_FGFR_FGFR2_Y	P35222	CTNNB1	P21802	FGFR2	Y748	D755Y	755	Missense	distal	7	no	1.346	1.358	EPSD	COSMIC	1.189	Up-regulation
TK_FGFR_FGFR2_Y	P35222	CTNNB1	P21802	FGFR2	Y748	D751N	751	Missense	distal	3	no	1.346	1.105	EPSD	COSMIC	1.189	Loss
TK_FGFR_FGFR2_Y	P35222	CTNNB1	P21802	FGFR2	Y748	D755V	755	Missense	distal	7	no	1.346	1.365	EPSD	COSMIC;CCLE	1.189	Up-regulation
TK_FGFR_FGFR2_Y	P35222	CTNNB1	P21802	FGFR2	Y748	H742Y	742	Missense	distal	-6	no	1.346	1.557	EPSD	COSMIC	1.189	Up-regulation
TK_FGFR_FGFR2_Y	P35222	CTNNB1	P21802	FGFR2	Y748	D755H	755	Missense	distal	7	no	1.346	1.367	EPSD	COSMIC	1.189	Up-regulation
TK_FGFR_FGFR2_Y	P60484	PTEN	P21802	FGFR2	Y240	R234Q	234	Missense	distal	-6	no	3.649	3.328	PhosphoSitePlus	COSMIC	1.189	Down-regulation
TK_FGFR_FGFR2_Y	P60484	PTEN	P21802	FGFR2	Y240	D236E	236	Missense	distal	-4	no	3.649	3.747	PhosphoSitePlus	COSMIC	1.189	Up-regulation
TK_FGFR_FGFR2_Y	P60484	PTEN	P21802	FGFR2	Y240	F241V	241	Missense	proximal	1	no	3.649	3.643	PhosphoSitePlus	COSMIC	1.189	Down-regulation
TK_FGFR_FGFR2_Y	P60484	PTEN	P21802	FGFR2	Y240	F238L	238	Missense	proximal	-2	no	3.649	3.648	PhosphoSitePlus	COSMIC	1.189	Down-regulation
TK_FGFR_FGFR2_Y	P60484	PTEN	P21802	FGFR2	Y240	E242K	242	Missense	proximal	2	no	3.649	3.777	PhosphoSitePlus	COSMIC	1.189	Up-regulation
TK_FGFR_FGFR2_Y	P60484	PTEN	P21802	FGFR2	Y240	R233G	233	Missense	distal	-7	no	3.649	3.569	PhosphoSitePlus	COSMIC;CCLE	1.189	Down-regulation
TK_FGFR_FGFR2_Y	P60484	PTEN	P21802	FGFR2	Y240	R234G	234	Missense	distal	-6	no	3.649	3.378	PhosphoSitePlus	COSMIC;CCLE	1.189	Down-regulation
TK_FGFR_FGFR2_Y	P60484	PTEN	P21802	FGFR2	Y240	F243L	243	Missense	distal	3	no	3.649	3.534	PhosphoSitePlus	COSMIC	1.189	Down-regulation
TK_FGFR_FGFR2_Y	P60484	PTEN	P21802	FGFR2	Y240	E235G	235	Missense	distal	-5	no	3.649	3.657	PhosphoSitePlus	COSMIC	1.189	Up-regulation
TK_FGFR_FGFR2_Y	P60484	PTEN	P21802	FGFR2	Y240	R234W	234	Missense	distal	-6	no	3.649	3.507	PhosphoSitePlus	COSMIC	1.189	Down-regulation
TK_FGFR_FGFR2_Y	P60484	PTEN	P21802	FGFR2	Y240	E235K	235	Missense	distal	-5	no	3.649	3.652	PhosphoSitePlus	COSMIC	1.189	Up-regulation
TK_FGFR_FGFR2_Y	P60484	PTEN	P21802	FGFR2	Y240	R234L	234	Missense	distal	-6	no	3.649	3.291	PhosphoSitePlus	COSMIC	1.189	Down-regulation
TK_FGFR_FGFR2_Y	P60484	PTEN	P21802	FGFR2	Y240	F241L	241	Missense	proximal	1	no	3.649	3.644	PhosphoSitePlus	COSMIC;GDSC;CCLE	1.189	Down-regulation
TK_FGFR_FGFR2_Y	P60484	PTEN	P21802	FGFR2	Y240	P244S	244	Missense	distal	4	no	3.649	3.652	PhosphoSitePlus	COSMIC	1.189	Up-regulation
TK_FGFR_FGFR2_Y	P60484	PTEN	P21802	FGFR2	Y240	L247S	247	Missense	distal	7	no	3.649	3.637	PhosphoSitePlus	COSMIC	1.189	Down-regulation
TK_FGFR_FGFR2_Y	P62993	GRB2	P21802	FGFR2	Y7	F9L	9	Missense	proximal	2	no	1.633	1.599	EPSD	COSMIC	1.189	Down-regulation
CAMK_CAMKL_BRSK_BRSK1_ST	Q8TDC3	BRSK1	Q8TDC3-2	BRSK1	T189	S190N	190	Missense	proximal	1	no	1.236	1.125	EPSD	COSMIC	0.579	Down-regulation
CAMK_CAMKL_BRSK_BRSK1_ST	Q8TDC3	BRSK1	Q8TDC3-2	BRSK1	T189	P194L	194	Missense	distal	5	no	1.236	1.270	EPSD	COSMIC	0.579	Up-regulation
CAMK_CAMKL_BRSK_BRSK1_ST	Q8TDC3	BRSK1	Q8TDC3-2	BRSK1	T189	G183E	183	Missense	distal	-6	no	1.236	1.256	EPSD	COSMIC	0.579	Up-regulation
CAMK_CAMKL_BRSK_BRSK1_ST	Q8TDC3	BRSK1	Q8TDC3-2	BRSK1	S193	S190N	190	Missense	distal	-3	no	1.181	1.175	EPSD	COSMIC	0.579	Down-regulation
CAMK_CAMKL_BRSK_BRSK1_ST	Q8TDC3	BRSK1	Q8TDC3-2	BRSK1	S193	E200D	200	Missense	distal	7	no	1.181	1.166	EPSD	COSMIC	0.579	Down-regulation
CAMK_CAMKL_BRSK_BRSK1_ST	Q8TDC3	BRSK1	Q8TDC3-2	BRSK1	S193	P194L	194	Missense	proximal	1	no	1.181	1.239	EPSD	COSMIC	0.579	Up-regulation
CAMK_CAMKL_BRSK_BRSK1_ST	Q8TDC3	BRSK1	Q8TDC3-2	BRSK1	S275	K272I	272	Missense	distal	-3	no	0.690	0.681	EPSD	COSMIC	0.579	Down-regulation
CAMK_CAMKL_BRSK_BRSK1_ST	Q8TDC3	BRSK1	Q8TDC3-2	BRSK1	S311	G313R	313	Missense	proximal	2	no	0.675	0.669	EPSD	COSMIC	0.579	Down-regulation
CAMK_CAMKL_BRSK_BRSK1_ST	Q8TDC3	BRSK1	Q8TDC3-2	BRSK1	S311	G313E	313	Missense	proximal	2	no	0.675	0.699	EPSD	COSMIC	0.579	Up-regulation
CAMK_CAMKL_BRSK_BRSK1_ST	Q8TDC3	BRSK1	Q8TDC3-2	BRSK1	S311	D318Y	318	Missense	distal	7	no	0.675	0.683	EPSD	COSMIC	0.579	Up-regulation
CAMK_CAMKL_BRSK_BRSK1_ST	Q8TDC3	BRSK1	Q8TDC3-2	BRSK1	S388	P385L	385	Missense	distal	-3	no	0.731	0.737	EPSD	COSMIC	0.579	Up-regulation
CAMK_CAMKL_BRSK_BRSK1_ST	Q8TDC3	BRSK1	Q8TDC3-2	BRSK1	S388	G391E	391	Missense	distal	3	no	0.731	0.675	EPSD	COSMIC;GDSC;CCLE	0.579	Down-regulation
CAMK_CAMKL_BRSK_BRSK1_ST	Q8TDC3	BRSK1	Q8TDC3-2	BRSK1	S388	G391R	391	Missense	distal	3	no	0.731	0.665	EPSD	COSMIC	0.579	Down-regulation
CAMK_CAMKL_BRSK_BRSK1_ST	Q8TDC3	BRSK1	Q8TDC3-2	BRSK1	S388	D383Y	383	Missense	distal	-5	no	0.731	0.720	EPSD	COSMIC	0.579	Down-regulation
CAMK_CAMKL_BRSK_BRSK1_ST	Q8TDC3	BRSK1	Q8TDC3-2	BRSK1	S388	R389H	389	Missense	proximal	1	no	0.731	0.681	EPSD	COSMIC	0.579	Down-regulation
CAMK_CAMKL_BRSK_BRSK1_ST	Q8TDC3	BRSK1	Q8TDC3-2	BRSK1	S388	M386I	386	Missense	proximal	-2	no	0.731	0.672	EPSD	COSMIC	0.579	Down-regulation
CAMK_CAMKL_BRSK_BRSK1_ST	Q8TDC3	BRSK1	Q8TDC3-2	BRSK1	S404	S399F	399	Missense	distal	-5	no	0.565	0.617	EPSD	COSMIC	0.579	Gain
CAMK_CAMKL_BRSK_BRSK1_ST	Q8TDC3	BRSK1	Q8TDC3-2	BRSK1	T406	S413F	413	Missense	distal	7	no	0.778	0.763	EPSD	COSMIC	0.579	Down-regulation
CAMK_CAMKL_BRSK_BRSK1_ST	Q8TDC3	BRSK1	Q8TDC3-2	BRSK1	T406	G410R	410	Missense	distal	4	no	0.778	0.777	EPSD	COSMIC	0.579	Down-regulation
CAMK_CAMKL_BRSK_BRSK1_ST	Q8TDC3	BRSK1	Q8TDC3-2	BRSK1	T406	S404C	404	Missense	proximal	-2	no	0.778	0.696	EPSD	COSMIC	0.579	Down-regulation
CAMK_CAMKL_BRSK_BRSK1_ST	Q8TDC3	BRSK1	Q8TDC3-2	BRSK1	T406	S399F	399	Missense	distal	-7	no	0.778	0.791	EPSD	COSMIC	0.579	Up-regulation
CAMK_CAMKL_BRSK_BRSK1_ST	Q8TDC3	BRSK1	Q8TDC3-2	BRSK1	S442	R449M	449	Missense	distal	7	no	0.607	0.620	EPSD	COSMIC	0.579	Up-regulation
CAMK_CAMKL_BRSK_BRSK1_ST	Q8TDC3	BRSK1	Q8TDC3-2	BRSK1	S442	A436V	436	Missense	distal	-6	no	0.607	0.680	EPSD	COSMIC	0.579	Up-regulation
CAMK_CAMKL_BRSK_BRSK1_ST	Q8TDC3	BRSK1	Q8TDC3-2	BRSK1	S446	R449M	449	Missense	distal	3	no	0.571	0.591	EPSD	COSMIC	0.579	Gain
CAMK_CAMKL_BRSK_BRSK1_ST	Q8TDC3	BRSK1	Q8TDC3-2	BRSK1	S446	P451L	451	Missense	distal	5	no	0.571	0.605	EPSD	COSMIC	0.579	Gain
CAMK_CAMKL_BRSK_BRSK1_ST	Q8TDC3	BRSK1	Q8TDC3-2	BRSK1	T500	P506S	506	Missense	distal	6	no	0.587	0.490	EPSD	COSMIC	0.579	Loss
CAMK_CAMKL_BRSK_BRSK1_ST	Q8TDC3	BRSK1	Q8TDC3-2	BRSK1	T500	P493Q	493	Missense	distal	-7	no	0.587	0.579	EPSD	COSMIC	0.579	Down-regulation
CAMK_CAMKL_BRSK_BRSK1_ST	Q8TDC3	BRSK1	Q8TDC3-2	BRSK1	T500	P493L	493	Missense	distal	-7	no	0.587	0.582	EPSD	COSMIC	0.579	Down-regulation
CAMK_CAMKL_BRSK_BRSK1_ST	Q8TDC3	BRSK1	Q8TDC3-2	BRSK1	S508	P506S	506	Missense	proximal	-2	no	0.419	0.614	EPSD	COSMIC	0.579	Gain
CAMK_CAMKL_BRSK_BRSK1_ST	Q8TDC3	BRSK1	Q8TDC3-2	BRSK1	S511	P509Q	509	Missense	proximal	-2	no	0.573	0.646	EPSD	COSMIC	0.579	Gain
CAMK_CAMKL_BRSK_BRSK1_ST	Q8TDC3	BRSK1	Q8TDC3-2	BRSK1	S511	P509L	509	Missense	proximal	-2	no	0.573	0.728	EPSD	COSMIC	0.579	Gain
CAMK_CAMKL_BRSK_BRSK1_ST	Q8TDC3	BRSK1	Q8TDC3-2	BRSK1	S519	G514R	514	Missense	distal	-5	no	0.672	0.663	EPSD	COSMIC	0.579	Down-regulation
CAMK_CAMKL_BRSK_BRSK1_ST	Q8TDC3	BRSK1	Q8TDC3-2	BRSK1	S519	R525W	525	Missense	distal	6	no	0.672	0.737	EPSD	COSMIC	0.579	Up-regulation
CAMK_CAMKL_BRSK_BRSK1_ST	Q8TDC3	BRSK1	Q8TDC3-2	BRSK1	S519	T523M	523	Missense	distal	4	no	0.672	0.692	EPSD	COSMIC	0.579	Up-regulation
CAMK_CAMKL_BRSK_BRSK1_ST	Q8TDC3	BRSK1	Q8TDC3-2	BRSK1	T575	R569H	569	Missense	distal	-6	no	0.588	0.474	EPSD	COSMIC	0.579	Loss
CAMK_CAMKL_BRSK_BRSK1_ST	Q8TDC3	BRSK1	Q8TDC3-2	BRSK1	T575	S580C	580	Missense	distal	5	no	0.588	0.641	EPSD	COSMIC	0.579	Up-regulation
CAMK_CAMKL_BRSK_BRSK1_ST	Q8TDC3	BRSK1	Q8TDC3-2	BRSK1	T575	R568H	568	Missense	distal	-7	no	0.588	0.595	EPSD	COSMIC	0.579	Up-regulation
CAMK_CAMKL_BRSK_BRSK1_ST	Q8TDC3	BRSK1	Q8TDC3-2	BRSK1	S580	P584S	584	Missense	distal	4	no	0.639	0.668	EPSD	COSMIC	0.579	Up-regulation
CAMK_CAMKL_BRSK_BRSK1_ST	Q8TDC3	BRSK1	Q8TDC3-2	BRSK1	S580	S580C	580	Missense	central	0	yes	0.639	0.000	EPSD	COSMIC	0.579	Loss
CAMK_CAMKL_BRSK_BRSK1_ST	Q8TDC3	BRSK1	Q8TDC3-2	BRSK1	S580	S586F	586	Missense	distal	6	no	0.639	0.679	EPSD	COSMIC	0.579	Up-regulation
CAMK_CAMKL_BRSK_BRSK1_ST	Q8TDC3	BRSK1	Q8TDC3-2	BRSK1	T583	P588L	588	Missense	distal	5	no	0.653	0.687	EPSD	COSMIC	0.579	Up-regulation
CAMK_CAMKL_BRSK_BRSK1_ST	Q8TDC3	BRSK1	Q8TDC3-2	BRSK1	T583	P588Q	588	Missense	distal	5	no	0.653	0.620	EPSD	COSMIC;GDSC;CCLE	0.579	Down-regulation
CAMK_CAMKL_BRSK_BRSK1_ST	Q8TDC3	BRSK1	Q8TDC3-2	BRSK1	T583	P584S	584	Missense	proximal	1	no	0.653	0.759	EPSD	COSMIC	0.579	Up-regulation
CAMK_CAMKL_BRSK_BRSK1_ST	Q8TDC3	BRSK1	Q8TDC3-2	BRSK1	T583	S580C	580	Missense	distal	-3	no	0.653	0.639	EPSD	COSMIC	0.579	Down-regulation
CAMK_CAMKL_BRSK_BRSK1_ST	Q8TDC3	BRSK1	Q8TDC3-2	BRSK1	T583	S586F	586	Missense	distal	3	no	0.653	0.710	EPSD	COSMIC	0.579	Up-regulation
CAMK_CAMKL_BRSK_BRSK1_ST	Q8TDC3	BRSK1	Q8TDC3-2	BRSK1	T583	P588T	588	Missense	distal	5	no	0.653	0.624	EPSD	COSMIC	0.579	Down-regulation
CAMK_CAMKL_BRSK_BRSK1_ST	Q8TDC3	BRSK1	Q8TDC3-2	BRSK1	S676	P677S	677	Missense	proximal	1	no	0.545	0.651	EPSD	COSMIC	0.579	Gain
CAMK_CAMKL_BRSK_BRSK1_ST	Q8TDC3	BRSK1	Q8TDC3-2	BRSK1	S676	P677L	677	Missense	proximal	1	no	0.545	0.604	EPSD	COSMIC	0.579	Gain
CAMK_CAMKL_BRSK_BRSK1_ST	Q8TDC3	BRSK1	Q8TDC3-2	BRSK1	T691	V690I	690	Missense	proximal	-1	no	0.794	0.815	EPSD	COSMIC	0.579	Up-regulation
CAMK_CAMKL_BRSK_BRSK1_ST	Q8TDC3	BRSK1	Q8TDC3-2	BRSK1	T691	L694V	694	Missense	distal	3	no	0.794	0.846	EPSD	COSMIC	0.579	Up-regulation
CAMK_CAMKL_BRSK_BRSK1_ST	Q8TDC3	BRSK1	Q8TDC3-2	BRSK1	T691	G697D	697	Missense	distal	6	no	0.794	0.774	EPSD	COSMIC	0.579	Down-regulation
CAMK_CAMKL_BRSK_BRSK1_ST	Q13131	PRKAA1	Q8TDC3-2	BRSK1	S254	N249H	249	Missense	distal	-5	no	0.764	0.734	EPSD	COSMIC	0.579	Down-regulation
CAMK_CAMKL_BRSK_BRSK1_ST	Q13131	PRKAA1	Q8TDC3-2	BRSK1	S254	L248F	248	Missense	distal	-6	no	0.764	0.676	EPSD	COSMIC	0.579	Down-regulation
CAMK_CAMKL_BRSK_BRSK1_ST	Q13131	PRKAA1	Q8TDC3-2	BRSK1	S496	V497A	497	Missense	proximal	1	no	0.657	0.655	EPSD	COSMIC	0.579	Down-regulation
CAMK_CAMKL_BRSK_BRSK1_ST	Q13131	PRKAA1	Q8TDC3-2	BRSK1	S496	R501G	501	Missense	distal	5	no	0.657	0.696	EPSD	COSMIC	0.579	Up-regulation
CAMK_CAMKL_BRSK_BRSK1_ST	Q13131	PRKAA1	Q8TDC3-2	BRSK1	S498	R501G	501	Missense	distal	3	no	0.561	0.626	EPSD	COSMIC	0.579	Gain
CAMK_CAMKL_BRSK_BRSK1_ST	Q13131	PRKAA1	Q8TDC3-2	BRSK1	S523	S524F	524	Missense	proximal	1	no	0.695	0.609	EPSD	COSMIC	0.579	Down-regulation
CAMK_CAMKL_BRSK_BRSK1_ST	Q13131	PRKAA1	Q8TDC3-2	BRSK1	T526	S524F	524	Missense	proximal	-2	no	0.642	0.487	EPSD	COSMIC	0.579	Loss
CAMK_CAMKL_BRSK_BRSK1_ST	Q13131	PRKAA1	Q8TDC3-2	BRSK1	T526	S531F	531	Missense	distal	5	no	0.642	0.679	EPSD	COSMIC	0.579	Up-regulation
CAMK_CAMKL_BRSK_BRSK1_ST	Q13131	PRKAA1	Q8TDC3-2	BRSK1	S527	S524F	524	Missense	distal	-3	no	0.676	0.661	EPSD	COSMIC	0.579	Down-regulation
CAMK_CAMKL_BRSK_BRSK1_ST	Q13131	PRKAA1	Q8TDC3-2	BRSK1	S527	S531F	531	Missense	distal	4	no	0.676	0.660	EPSD	COSMIC	0.579	Down-regulation
CAMK_CAMKL_BRSK_BRSK1_ST	Q13131	PRKAA1	Q8TDC3-2	BRSK1	S530	S524F	524	Missense	distal	-6	no	0.688	0.683	EPSD	COSMIC	0.579	Down-regulation
CAMK_CAMKL_BRSK_BRSK1_ST	Q13131	PRKAA1	Q8TDC3-2	BRSK1	S530	S531F	531	Missense	proximal	1	no	0.688	0.602	EPSD	COSMIC	0.579	Down-regulation
CAMK_CAMKL_BRSK_BRSK1_ST	Q13131	PRKAA1	Q8TDC3-2	BRSK1	S541	P539S	539	Missense	proximal	-2	no	0.411	0.606	EPSD	COSMIC	0.579	Gain
CAMK_CAMKL_BRSK_BRSK1_ST	P30291	WEE1	Q8TDC3-2	BRSK1	T278	D271G	271	Missense	distal	-7	no	0.653	0.655	EPSD	COSMIC	0.579	Up-regulation
CAMK_CAMKL_BRSK_BRSK1_ST	P30291	WEE1	Q8TDC3-2	BRSK1	S571	A577T	577	Missense	distal	6	no	0.650	0.691	EPSD	COSMIC;CCLE	0.579	Up-regulation
CAMK_CAMKL_BRSK_BRSK1_ST	P30291	WEE1	Q8TDC3-2	BRSK1	S642	R639H	639	Missense	distal	-3	no	0.793	0.790	PhosphoSitePlus	COSMIC	0.579	Down-regulation
CAMK_CAMKL_BRSK_BRSK1_ST	P23258	TUBG1	Q8TDC3-2	BRSK1	S131	R124W	124	Missense	distal	-7	no	1.301	1.315	PhosphoSitePlus	COSMIC	0.579	Up-regulation
CAMK_CAMKL_BRSK_BRSK1_ST	P30305	CDC25B	Q8TDC3-2	BRSK1	T58	P51L	51	Missense	distal	-7	no	0.721	0.716	EPSD	COSMIC	0.579	Down-regulation
CAMK_CAMKL_BRSK_BRSK1_ST	P30305	CDC25B	Q8TDC3-2	BRSK1	T58	Q57R	57	Missense	proximal	-1	no	0.721	0.783	EPSD	COSMIC	0.579	Up-regulation
CAMK_CAMKL_BRSK_BRSK1_ST	P30305	CDC25B	Q8TDC3-2	BRSK1	S89	S83I	83	Missense	distal	-6	no	0.506	0.585	EPSD	COSMIC	0.579	Gain
CAMK_CAMKL_BRSK_BRSK1_ST	P30305	CDC25B	Q8TDC3-2	BRSK1	S115	A109V	109	Missense	distal	-6	no	0.711	0.783	EPSD	COSMIC	0.579	Up-regulation
CAMK_CAMKL_BRSK_BRSK1_ST	P30305	CDC25B	Q8TDC3-2	BRSK1	S323	S323N	323	Missense	central	0	yes	0.747	0.000	EPSD	COSMIC	0.579	Loss
CAMK_CAMKL_BRSK_BRSK1_ST	P30305	CDC25B	Q8TDC3-2	BRSK1	S323	P325L	325	Missense	proximal	2	no	0.747	0.740	EPSD	COSMIC	0.579	Down-regulation
CAMK_CAMKL_BRSK_BRSK1_ST	P30305	CDC25B	Q8TDC3-2	BRSK1	S323	R320G	320	Missense	distal	-3	no	0.747	0.737	EPSD	COSMIC	0.579	Down-regulation
CAMK_CAMKL_BRSK_BRSK1_ST	P30305	CDC25B	Q8TDC3-2	BRSK1	S323	S321F	321	Missense	proximal	-2	no	0.747	0.592	EPSD	COSMIC	0.579	Down-regulation
CAMK_CAMKL_BRSK_BRSK1_ST	P30305	CDC25B	Q8TDC3-2	BRSK1	S323	R330Q	330	Missense	distal	7	no	0.747	0.766	EPSD	COSMIC	0.579	Up-regulation
CAMK_CAMKL_BRSK_BRSK1_ST	P30305	CDC25B	Q8TDC3-2	BRSK1	S323	P322L	322	Missense	proximal	-1	no	0.747	0.768	EPSD	COSMIC	0.579	Up-regulation
CAMK_CAMKL_BRSK_BRSK1_ST	P30305	CDC25B	Q8TDC3-2	BRSK1	S323	R317W	317	Missense	distal	-6	no	0.747	0.703	EPSD	COSMIC	0.579	Down-regulation
CAMK_CAMKL_BRSK_BRSK1_ST	P30305	CDC25B	Q8TDC3-2	BRSK1	T355	R352Q	352	Missense	distal	-3	no	0.630	0.623	EPSD	COSMIC	0.579	Down-regulation
CAMK_CAMKL_BRSK_BRSK1_ST	P30305	CDC25B	Q8TDC3-2	BRSK1	T355	R350T	350	Missense	distal	-5	no	0.630	0.643	EPSD	COSMIC	0.579	Up-regulation
CAMK_CAMKL_BRSK_BRSK1_ST	P30305	CDC25B	Q8TDC3-2	BRSK1	S375	S373N	373	Missense	proximal	-2	no	1.213	1.066	PhosphoSitePlus	COSMIC	0.579	Down-regulation
CAMK_CAMKL_BRSK_BRSK1_ST	P30305	CDC25B	Q8TDC3-2	BRSK1	S375	R372C	372	Missense	distal	-3	no	1.213	1.205	PhosphoSitePlus	COSMIC	0.579	Down-regulation
CAMK_CAMKL_BRSK_BRSK1_ST	P30305	CDC25B	Q8TDC3-2	BRSK1	S375	V370I	370	Missense	distal	-5	no	1.213	1.224	PhosphoSitePlus	COSMIC;GDSC;CCLE	0.579	Up-regulation
CAMK_CAMKL_BRSK_BRSK1_ST	P30305	CDC25B	Q8TDC3-2	BRSK1	S375	E380K	380	Missense	distal	5	no	1.213	1.231	PhosphoSitePlus	COSMIC	0.579	Up-regulation
CAMK_CAMKL_BRSK_BRSK1_ST	P30305	CDC25B	Q8TDC3-2	BRSK1	S397	A399V	399	Missense	proximal	2	no	0.696	0.677	EPSD	COSMIC	0.579	Down-regulation
CAMK_CAMKL_BRSK_BRSK1_ST	P30307	CDC25C	Q8TDC3-2	BRSK1	S168	S168F	168	Missense	central	0	yes	0.633	0.000	EPSD	COSMIC	0.579	Loss
CAMK_CAMKL_BRSK_BRSK1_ST	P30307	CDC25C	Q8TDC3-2	BRSK1	S168	S161L	161	Missense	distal	-7	no	0.633	0.646	EPSD	COSMIC	0.579	Up-regulation
CAMK_CAMKL_BRSK_BRSK1_ST	P30307	CDC25C	Q8TDC3-2	BRSK1	S207	G210R	210	Missense	distal	3	no	0.747	0.682	EPSD	COSMIC	0.579	Down-regulation
CAMK_CAMKL_BRSK_BRSK1_ST	P30307	CDC25C	Q8TDC3-2	BRSK1	S216	S216L	216	Missense	central	0	yes	1.279	0.000	PhosphoSitePlus	COSMIC	0.579	Loss
CAMK_CAMKL_BRSK_BRSK1_ST	P30307	CDC25C	Q8TDC3-2	BRSK1	S216	G210R	210	Missense	distal	-6	no	1.279	1.309	PhosphoSitePlus	COSMIC	0.579	Up-regulation
CAMK_CAMKL_BRSK_BRSK1_ST	P30307	CDC25C	Q8TDC3-2	BRSK1	S451	R448Q	448	Missense	distal	-3	no	0.689	0.682	EPSD	COSMIC	0.579	Down-regulation
TK_Ack_TNK2_Y	P10275	AR	Q07912	TNK2	Y225	Y225D	225	Missense	central	0	yes	0.000	0.000	EPSD	COSMIC	0.000	Loss
TK_Ack_TNK2_Y	P10275	AR	Q07912	TNK2	Y364	Y364N	364	Missense	central	0	yes	0.000	0.000	EPSD	COSMIC	0.000	Loss
TK_Ack_TNK2_Y	P10275	AR	Q07912	TNK2	Y504	Y504C	504	Missense	central	0	yes	0.000	0.000	EPSD	COSMIC;CCLE	0.000	Loss
TK_Ack_TNK2_Y	P10275	AR	Q07912	TNK2	Y552	Y552H	552	Missense	central	0	yes	0.000	0.000	EPSD	COSMIC;GDSC;CCLE	0.000	Loss
TK_Ack_TNK2_Y	Q07912	TNK2	Q07912	TNK2	Y859	Y859S	859	Missense	central	0	yes	0.000	0.000	EPSD	COSMIC;CCLE	0.000	Loss
AGC_Akt_AKT3_ST	Q9UKV8	AGO2	Q9Y243	AKT3	S387	Y393H	393	Missense	distal	6	no	8.468	8.456	PhosphoSitePlus	COSMIC	2.840	Down-regulation
AGC_Akt_AKT3_ST	Q9UKV8	AGO2	Q9Y243	AKT3	S798	P802Q	802	Missense	distal	4	no	3.376	3.366	EPSD	COSMIC	2.840	Down-regulation
AGC_Akt_AKT3_ST	Q96ST2	IWS1	Q9Y243	AKT3	S329	K326R	326	Missense	distal	-3	no	2.629	4.471	EPSD	COSMIC	2.840	Gain
AGC_Akt_AKT3_ST	Q96ST2	IWS1	Q9Y243	AKT3	S415	D416N	416	Missense	proximal	1	no	3.508	3.516	EPSD	COSMIC	2.840	Up-regulation
AGC_Akt_AKT3_ST	Q96ST2	IWS1	Q9Y243	AKT3	T435	S429L	429	Missense	distal	-6	no	4.093	3.958	EPSD	COSMIC	2.840	Down-regulation
AGC_Akt_AKT3_ST	Q96ST2	IWS1	Q9Y243	AKT3	S465	E469K	469	Missense	distal	4	no	3.133	3.173	EPSD	COSMIC	2.840	Up-regulation
AGC_Akt_AKT3_ST	Q96ST2	IWS1	Q9Y243	AKT3	S513	E507K	507	Missense	distal	-6	no	3.554	3.532	EPSD	COSMIC	2.840	Down-regulation
AGC_Akt_AKT3_ST	O15119	TBX3	Q9Y243	AKT3	T399	S396T	396	Missense	distal	-3	no	3.265	3.404	EPSD	COSMIC	2.840	Up-regulation
AGC_Akt_AKT3_ST	O15119	TBX3	Q9Y243	AKT3	T399	E402K	402	Missense	distal	3	no	3.265	3.365	EPSD	COSMIC	2.840	Up-regulation
AGC_Akt_AKT3_ST	O15119	TBX3	Q9Y243	AKT3	T399	R405L	405	Missense	distal	6	no	3.265	3.180	EPSD	COSMIC	2.840	Down-regulation
AGC_Akt_AKT3_ST	O15119	TBX3	Q9Y243	AKT3	T399	R405S	405	Missense	distal	6	no	3.265	3.178	EPSD	COSMIC;CCLE	2.840	Down-regulation
AGC_Akt_AKT3_ST	O15119	TBX3	Q9Y243	AKT3	T399	S396F	396	Missense	distal	-3	no	3.265	3.345	EPSD	COSMIC	2.840	Up-regulation
AGC_Akt_AKT3_ST	O15119	TBX3	Q9Y243	AKT3	T399	T398I	398	Missense	proximal	-1	no	3.265	2.604	EPSD	COSMIC	2.840	Loss
AGC_Akt_AKT3_ST	O15119	TBX3	Q9Y243	AKT3	T399	R405G	405	Missense	distal	6	no	3.265	3.187	EPSD	COSMIC	2.840	Down-regulation
AGC_Akt_AKT3_ST	O15119	TBX3	Q9Y243	AKT3	T399	S396C	396	Missense	distal	-3	no	3.265	3.476	EPSD	COSMIC	2.840	Up-regulation
AGC_Akt_AKT3_ST	O15119	TBX3	Q9Y243	AKT3	T399	S396P	396	Missense	distal	-3	no	3.265	3.474	EPSD	COSMIC	2.840	Up-regulation
AGC_Akt_AKT3_ST	O15119	TBX3	Q9Y243	AKT3	S432	R427H	427	Missense	distal	-5	no	3.279	2.146	EPSD	COSMIC	2.840	Loss
AGC_Akt_AKT3_ST	O15119	TBX3	Q9Y243	AKT3	S432	A431T	431	Missense	proximal	-1	no	3.279	3.136	EPSD	COSMIC	2.840	Down-regulation
AGC_Akt_AKT3_ST	O15119	TBX3	Q9Y243	AKT3	S432	D434E	434	Missense	proximal	2	no	3.279	3.444	EPSD	COSMIC	2.840	Up-regulation
AGC_Akt_AKT3_ST	O15119	TBX3	Q9Y243	AKT3	S432	S425G	425	Missense	distal	-7	no	3.279	3.175	EPSD	COSMIC	2.840	Down-regulation
AGC_Akt_AKT3_ST	O15119	TBX3	Q9Y243	AKT3	S432	D429H	429	Missense	distal	-3	no	3.279	3.433	EPSD	COSMIC	2.840	Up-regulation
AGC_Akt_AKT3_ST	O15119	TBX3	Q9Y243	AKT3	S432	R427Q	427	Missense	distal	-5	no	3.279	2.092	EPSD	COSMIC;CCLE	2.840	Loss
AGC_Akt_AKT3_ST	O15119	TBX3	Q9Y243	AKT3	S432	G426W	426	Missense	distal	-6	no	3.279	3.189	EPSD	COSMIC;GDSC;CCLE	2.840	Down-regulation
AGC_Akt_AKT3_ST	O15119	TBX3	Q9Y243	AKT3	S432	P433R	433	Missense	proximal	1	no	3.279	3.258	EPSD	COSMIC	2.840	Down-regulation
AGC_Akt_AKT3_ST	O15119	TBX3	Q9Y243	AKT3	S432	R436L	436	Missense	distal	4	no	3.279	3.232	EPSD	COSMIC	2.840	Down-regulation
AGC_Akt_AKT3_ST	O15119	TBX3	Q9Y243	AKT3	S432	R436H	436	Missense	distal	4	no	3.279	3.347	EPSD	COSMIC	2.840	Up-regulation
AGC_Akt_AKT3_ST	O15119	TBX3	Q9Y243	AKT3	S432	S438R	438	Missense	distal	6	no	3.279	3.366	EPSD	COSMIC	2.840	Up-regulation
AGC_Akt_AKT3_ST	O15119	TBX3	Q9Y243	AKT3	S432	D434N	434	Missense	proximal	2	no	3.279	3.580	EPSD	COSMIC	2.840	Up-regulation
AGC_Akt_AKT3_ST	O15119	TBX3	Q9Y243	AKT3	T441	S443L	443	Missense	proximal	2	no	2.450	2.921	EPSD	COSMIC	2.840	Gain
AGC_Akt_AKT3_ST	O15119	TBX3	Q9Y243	AKT3	T441	S438R	438	Missense	distal	-3	no	2.450	5.074	EPSD	COSMIC	2.840	Gain
AGC_Akt_AKT3_ST	O15119	TBX3	Q9Y243	AKT3	S443	R447H	447	Missense	distal	4	no	2.945	3.014	EPSD	COSMIC	2.840	Up-regulation
AGC_Akt_AKT3_ST	O15119	TBX3	Q9Y243	AKT3	S443	R436L	436	Missense	distal	-7	no	2.945	2.809	EPSD	COSMIC	2.840	Loss
AGC_Akt_AKT3_ST	O15119	TBX3	Q9Y243	AKT3	S443	R436H	436	Missense	distal	-7	no	2.945	2.867	EPSD	COSMIC	2.840	Down-regulation
AGC_Akt_AKT3_ST	O15119	TBX3	Q9Y243	AKT3	S443	G448S	448	Missense	distal	5	no	2.945	3.062	EPSD	COSMIC	2.840	Up-regulation
AGC_Akt_AKT3_ST	O15119	TBX3	Q9Y243	AKT3	S443	S443L	443	Missense	central	0	yes	2.945	0.000	EPSD	COSMIC	2.840	Loss
AGC_Akt_AKT3_ST	O15119	TBX3	Q9Y243	AKT3	S443	S438R	438	Missense	distal	-5	no	2.945	4.196	EPSD	COSMIC	2.840	Up-regulation
AGC_Akt_AKT3_ST	O15119	TBX3	Q9Y243	AKT3	S443	A440T	440	Missense	distal	-3	no	2.945	2.435	EPSD	COSMIC;CCLE	2.840	Loss
AGC_Akt_AKT3_ST	O15119	TBX3	Q9Y243	AKT3	T462	P464T	464	Missense	proximal	2	no	3.316	2.779	EPSD	COSMIC	2.840	Loss
AGC_Akt_AKT3_ST	O15119	TBX3	Q9Y243	AKT3	T462	R459S	459	Missense	distal	-3	no	3.316	0.693	EPSD	COSMIC	2.840	Loss
AGC_Akt_AKT3_ST	O15119	TBX3	Q9Y243	AKT3	T462	A463V	463	Missense	proximal	1	no	3.316	3.346	EPSD	COSMIC	2.840	Up-regulation
AGC_Akt_AKT3_ST	O15119	TBX3	Q9Y243	AKT3	T462	E469Q	469	Missense	distal	7	no	3.316	3.189	EPSD	COSMIC	2.840	Down-regulation
AGC_Akt_AKT3_ST	O15119	TBX3	Q9Y243	AKT3	T462	R459H	459	Missense	distal	-3	no	3.316	1.003	EPSD	COSMIC	2.840	Loss
AGC_Akt_AKT3_ST	O15119	TBX3	Q9Y243	AKT3	T462	R459C	459	Missense	distal	-3	no	3.316	0.904	EPSD	COSMIC	2.840	Loss
AGC_Akt_AKT3_ST	O15119	TBX3	Q9Y243	AKT3	T462	P464L	464	Missense	proximal	2	no	3.316	3.461	EPSD	COSMIC;CCLE	2.840	Up-regulation
AGC_Akt_AKT3_ST	O15119	TBX3	Q9Y243	AKT3	S680	S683F	683	Missense	distal	3	no	3.050	2.933	EPSD	COSMIC	2.840	Down-regulation
AGC_Akt_AKT3_ST	O15119	TBX3	Q9Y243	AKT3	S680	A685V	685	Missense	distal	5	no	3.050	2.965	EPSD	COSMIC	2.840	Down-regulation
AGC_Akt_AKT3_ST	O15119	TBX3	Q9Y243	AKT3	S680	A678V	678	Missense	proximal	-2	no	3.050	2.485	EPSD	COSMIC	2.840	Loss
AGC_Akt_AKT3_ST	O15119	TBX3	Q9Y243	AKT3	S680	A676S	676	Missense	distal	-4	no	3.050	3.043	EPSD	COSMIC	2.840	Down-regulation
AGC_Akt_AKT3_ST	O15119	TBX3	Q9Y243	AKT3	S680	A675T	675	Missense	distal	-5	no	3.050	2.764	EPSD	COSMIC	2.840	Loss
AGC_Akt_AKT3_ST	O15119	TBX3	Q9Y243	AKT3	S680	A679T	679	Missense	proximal	-1	no	3.050	2.907	EPSD	COSMIC	2.840	Down-regulation
AGC_Akt_AKT3_ST	O15119	TBX3	Q9Y243	AKT3	S680	A679P	679	Missense	proximal	-1	no	3.050	2.266	EPSD	COSMIC	2.840	Loss
AGC_Akt_AKT3_ST	O15119	TBX3	Q9Y243	AKT3	S680	V684M	684	Missense	distal	4	no	3.050	3.003	EPSD	COSMIC	2.840	Down-regulation
AGC_Akt_AKT3_ST	O15119	TBX3	Q9Y243	AKT3	S680	A675V	675	Missense	distal	-5	no	3.050	2.387	EPSD	COSMIC	2.840	Loss
AGC_Akt_AKT3_ST	O15119	TBX3	Q9Y243	AKT3	S680	S680R	680	Missense	central	0	yes	3.050	0.000	EPSD	COSMIC	2.840	Loss
AGC_Akt_AKT3_ST	O15119	TBX3	Q9Y243	AKT3	S680	D687H	687	Missense	distal	7	no	3.050	3.007	EPSD	COSMIC	2.840	Down-regulation
AGC_Akt_AKT3_ST	O15119	TBX3	Q9Y243	AKT3	S680	K673R	673	Missense	distal	-7	no	3.050	3.061	EPSD	COSMIC	2.840	Up-regulation
AGC_Akt_AKT3_ST	O15119	TBX3	Q9Y243	AKT3	S680	V686M	686	Missense	distal	6	no	3.050	3.038	EPSD	COSMIC	2.840	Down-regulation
AGC_Akt_AKT3_ST	O15119	TBX3	Q9Y243	AKT3	S680	V674G	674	Missense	distal	-6	no	3.050	3.089	EPSD	COSMIC	2.840	Up-regulation
AGC_Akt_AKT3_ST	O15119	TBX3	Q9Y243	AKT3	S680	A682S	682	Missense	proximal	2	no	3.050	2.993	EPSD	COSMIC	2.840	Down-regulation
AGC_Akt_AKT3_ST	O15119	TBX3	Q9Y243	AKT3	S683	S680R	680	Missense	distal	-3	no	2.028	4.651	EPSD	COSMIC	2.840	Gain
AGC_Akt_AKT3_ST	O15119	TBX3	Q9Y243	AKT3	S690	R695C	695	Missense	distal	5	no	2.797	2.980	EPSD	COSMIC	2.840	Gain
AGC_Akt_AKT3_ST	O15119	TBX3	Q9Y243	AKT3	S690	D687H	687	Missense	distal	-3	no	2.797	2.951	EPSD	COSMIC	2.840	Gain
AGC_Akt_AKT3_ST	O15119	TBX3	Q9Y243	AKT3	S690	N693K	693	Missense	distal	3	no	2.797	2.933	EPSD	COSMIC	2.840	Gain
AGC_Akt_AKT3_ST	O15119	TBX3	Q9Y243	AKT3	S690	N693S	693	Missense	distal	3	no	2.797	2.903	EPSD	COSMIC;GDSC	2.840	Gain
AGC_Akt_AKT3_ST	O15119	TBX3	Q9Y243	AKT3	S697	S694R	694	Missense	distal	-3	no	1.533	4.157	EPSD	COSMIC	2.840	Gain
AGC_Akt_AKT3_ST	O15119	TBX3	Q9Y243	AKT3	T698	S703C	703	Missense	distal	5	no	4.823	4.931	EPSD	COSMIC	2.840	Up-regulation
AGC_Akt_AKT3_ST	O15119	TBX3	Q9Y243	AKT3	T698	S702N	702	Missense	distal	4	no	4.823	4.704	EPSD	COSMIC	2.840	Down-regulation
AGC_Akt_AKT3_ST	O15119	TBX3	Q9Y243	AKT3	T698	R695C	695	Missense	distal	-3	no	4.823	2.411	EPSD	COSMIC	2.840	Loss
AGC_Akt_AKT3_ST	O15119	TBX3	Q9Y243	AKT3	T698	S694R	694	Missense	distal	-4	no	4.823	4.844	EPSD	COSMIC	2.840	Up-regulation
AGC_Akt_AKT3_ST	O15119	TBX3	Q9Y243	AKT3	T698	E691Q	691	Missense	distal	-7	no	4.823	4.816	EPSD	COSMIC	2.840	Down-regulation
AGC_Akt_AKT3_ST	O15119	TBX3	Q9Y243	AKT3	T698	M704T	704	Missense	distal	6	no	4.823	4.842	EPSD	COSMIC;CCLE	2.840	Up-regulation
AGC_Akt_AKT3_ST	O15119	TBX3	Q9Y243	AKT3	T698	N693K	693	Missense	distal	-5	no	4.823	5.399	EPSD	COSMIC	2.840	Up-regulation
AGC_Akt_AKT3_ST	O15119	TBX3	Q9Y243	AKT3	T698	E691D	691	Missense	distal	-7	no	4.823	4.858	EPSD	COSMIC	2.840	Up-regulation
AGC_Akt_AKT3_ST	O15119	TBX3	Q9Y243	AKT3	T698	S703F	703	Missense	distal	5	no	4.823	4.726	EPSD	COSMIC	2.840	Down-regulation
AGC_Akt_AKT3_ST	O15119	TBX3	Q9Y243	AKT3	T698	N693S	693	Missense	distal	-5	no	4.823	5.008	EPSD	COSMIC;GDSC	2.840	Up-regulation
AGC_Akt_AKT3_ST	O15119	TBX3	Q9Y243	AKT3	S700	S703C	703	Missense	distal	3	no	2.878	2.810	EPSD	COSMIC	2.840	Loss
AGC_Akt_AKT3_ST	O15119	TBX3	Q9Y243	AKT3	S700	S702N	702	Missense	proximal	2	no	2.878	3.290	EPSD	COSMIC	2.840	Up-regulation
AGC_Akt_AKT3_ST	O15119	TBX3	Q9Y243	AKT3	S700	R695C	695	Missense	distal	-5	no	2.878	1.689	EPSD	COSMIC	2.840	Loss
AGC_Akt_AKT3_ST	O15119	TBX3	Q9Y243	AKT3	S700	S694R	694	Missense	distal	-6	no	2.878	2.930	EPSD	COSMIC	2.840	Up-regulation
AGC_Akt_AKT3_ST	O15119	TBX3	Q9Y243	AKT3	S700	M704T	704	Missense	distal	4	no	2.878	3.051	EPSD	COSMIC;CCLE	2.840	Up-regulation
AGC_Akt_AKT3_ST	O15119	TBX3	Q9Y243	AKT3	S700	N693K	693	Missense	distal	-7	no	2.878	3.000	EPSD	COSMIC	2.840	Up-regulation
AGC_Akt_AKT3_ST	O15119	TBX3	Q9Y243	AKT3	S700	L706V	706	Missense	distal	6	no	2.878	2.890	EPSD	COSMIC;CCLE	2.840	Up-regulation
AGC_Akt_AKT3_ST	O15119	TBX3	Q9Y243	AKT3	S700	S703F	703	Missense	distal	3	no	2.878	2.761	EPSD	COSMIC	2.840	Loss
AGC_Akt_AKT3_ST	O15119	TBX3	Q9Y243	AKT3	S700	N693S	693	Missense	distal	-7	no	2.878	3.037	EPSD	COSMIC;GDSC	2.840	Up-regulation
AGC_Akt_AKT3_ST	O15119	TBX3	Q9Y243	AKT3	S702	S703C	703	Missense	proximal	1	no	2.940	2.965	EPSD	COSMIC	2.840	Up-regulation
AGC_Akt_AKT3_ST	O15119	TBX3	Q9Y243	AKT3	S702	S702N	702	Missense	central	0	yes	2.940	0.000	EPSD	COSMIC	2.840	Loss
AGC_Akt_AKT3_ST	O15119	TBX3	Q9Y243	AKT3	S702	R695C	695	Missense	distal	-7	no	2.940	2.831	EPSD	COSMIC	2.840	Loss
AGC_Akt_AKT3_ST	O15119	TBX3	Q9Y243	AKT3	S702	K709I	709	Missense	distal	7	no	2.940	3.075	EPSD	COSMIC	2.840	Up-regulation
AGC_Akt_AKT3_ST	O15119	TBX3	Q9Y243	AKT3	S702	M704T	704	Missense	proximal	2	no	2.940	2.412	EPSD	COSMIC;CCLE	2.840	Loss
AGC_Akt_AKT3_ST	O15119	TBX3	Q9Y243	AKT3	S702	L706V	706	Missense	distal	4	no	2.940	3.063	EPSD	COSMIC;CCLE	2.840	Up-regulation
AGC_Akt_AKT3_ST	O15119	TBX3	Q9Y243	AKT3	S702	S703F	703	Missense	proximal	1	no	2.940	2.972	EPSD	COSMIC	2.840	Up-regulation
AGC_Akt_AKT3_ST	O15119	TBX3	Q9Y243	AKT3	S703	L706V	706	Missense	distal	3	no	2.771	2.888	EPSD	COSMIC;CCLE	2.840	Gain
AGC_Akt_AKT3_ST	O15119	TBX3	Q9Y243	AKT3	S719	A712T	712	Missense	distal	-7	no	6.326	6.328	PhosphoSitePlus	COSMIC	2.840	Up-regulation
AGC_Akt_AKT3_ST	O15119	TBX3	Q9Y243	AKT3	S719	L721M	721	Missense	proximal	2	no	6.326	6.172	PhosphoSitePlus	COSMIC;CCLE	2.840	Down-regulation
AGC_Akt_AKT3_ST	O15119	TBX3	Q9Y243	AKT3	S719	R726W	726	Missense	distal	7	no	6.326	6.483	PhosphoSitePlus	COSMIC	2.840	Up-regulation
AGC_Akt_AKT3_ST	O15119	TBX3	Q9Y243	AKT3	S719	A716V	716	Missense	distal	-3	no	6.326	5.278	PhosphoSitePlus	COSMIC	2.840	Down-regulation
AGC_Akt_AKT3_ST	O15119	TBX3	Q9Y243	AKT3	S719	A716E	716	Missense	distal	-3	no	6.326	5.630	PhosphoSitePlus	COSMIC	2.840	Down-regulation
AGC_Akt_AKT3_ST	O15119	TBX3	Q9Y243	AKT3	S719	E715K	715	Missense	distal	-4	no	6.326	6.343	PhosphoSitePlus	COSMIC	2.840	Up-regulation
AGC_Akt_AKT3_ST	O15119	TBX3	Q9Y243	AKT3	S719	Q725K	725	Missense	distal	6	no	6.326	6.309	PhosphoSitePlus	COSMIC	2.840	Down-regulation
AGC_Akt_AKT3_ST	O15119	TBX3	Q9Y243	AKT3	S719	S723C	723	Missense	distal	4	no	6.326	6.213	PhosphoSitePlus	COSMIC	2.840	Down-regulation
AGC_Akt_AKT3_ST	O15119	TBX3	Q9Y243	AKT3	S729	R726W	726	Missense	distal	-3	no	3.665	0.999	EPSD	COSMIC	2.840	Loss
AGC_Akt_AKT3_ST	O15119	TBX3	Q9Y243	AKT3	S729	P735L	735	Missense	distal	6	no	3.665	3.643	EPSD	COSMIC	2.840	Down-regulation
AGC_Akt_AKT3_ST	O15119	TBX3	Q9Y243	AKT3	S729	L727F	727	Missense	proximal	-2	no	3.665	3.634	EPSD	COSMIC	2.840	Down-regulation
AGC_Akt_AKT3_ST	O15119	TBX3	Q9Y243	AKT3	S729	Q725K	725	Missense	distal	-4	no	3.665	3.673	EPSD	COSMIC	2.840	Up-regulation
AGC_Akt_AKT3_ST	O15119	TBX3	Q9Y243	AKT3	S729	G730V	730	Missense	proximal	1	no	3.665	3.657	EPSD	COSMIC	2.840	Down-regulation
AGC_Akt_AKT3_ST	O15119	TBX3	Q9Y243	AKT3	S729	D736E	736	Missense	distal	7	no	3.665	3.710	EPSD	COSMIC	2.840	Up-regulation
AGC_Akt_AKT3_ST	O15119	TBX3	Q9Y243	AKT3	S729	S723C	723	Missense	distal	-6	no	3.665	3.645	EPSD	COSMIC	2.840	Down-regulation
AGC_Akt_AKT3_ST	O15119	TBX3	Q9Y243	AKT3	S729	D736H	736	Missense	distal	7	no	3.665	3.622	EPSD	COSMIC	2.840	Down-regulation
AGC_Akt_AKT3_ST	O15119	TBX3	Q9Y243	AKT3	S729	S729R	729	Missense	central	0	yes	3.665	0.000	EPSD	COSMIC	2.840	Loss
AGC_Akt_AKT3_ST	O15119	TBX3	Q9Y243	AKT3	S729	D736N	736	Missense	distal	7	no	3.665	3.834	EPSD	COSMIC	2.840	Up-regulation
AGC_Akt_AKT3_ST	O15119	TBX3	Q9Y243	AKT3	S740	P735L	735	Missense	distal	-5	no	3.869	3.952	EPSD	COSMIC	2.840	Up-regulation
AGC_Akt_AKT3_ST	O15119	TBX3	Q9Y243	AKT3	S740	D736E	736	Missense	distal	-4	no	3.869	3.861	EPSD	COSMIC	2.840	Down-regulation
AGC_Akt_AKT3_ST	O15119	TBX3	Q9Y243	AKT3	S740	D736H	736	Missense	distal	-4	no	3.869	3.856	EPSD	COSMIC	2.840	Down-regulation
AGC_Akt_AKT3_ST	O15119	TBX3	Q9Y243	AKT3	S740	D736N	736	Missense	distal	-4	no	3.869	3.841	EPSD	COSMIC	2.840	Down-regulation
AGC_Akt_AKT3_ST	O15119	TBX3	Q9Y243	AKT3	S742	P735L	735	Missense	distal	-7	no	5.611	5.566	EPSD	COSMIC	2.840	Down-regulation
AGC_Akt_AKT3_ST	O15119	TBX3	Q9Y243	AKT3	S742	D736E	736	Missense	distal	-6	no	5.611	5.624	EPSD	COSMIC	2.840	Up-regulation
AGC_Akt_AKT3_ST	O15119	TBX3	Q9Y243	AKT3	S742	D736H	736	Missense	distal	-6	no	5.611	5.594	EPSD	COSMIC	2.840	Down-regulation
AGC_Akt_AKT3_ST	O15119	TBX3	Q9Y243	AKT3	S742	D736N	736	Missense	distal	-6	no	5.611	5.574	EPSD	COSMIC	2.840	Down-regulation
AGC_Akt_AKT3_ST	P15056	BRAF	Q9Y243	AKT3	S335	T332I	332	Missense	distal	-3	no	3.225	3.059	EPSD	COSMIC	2.840	Down-regulation
AGC_Akt_AKT3_ST	P15056	BRAF	Q9Y243	AKT3	S335	L331F	331	Missense	distal	-4	no	3.225	3.266	EPSD	COSMIC	2.840	Up-regulation
AGC_Akt_AKT3_ST	P15056	BRAF	Q9Y243	AKT3	S335	P334S	334	Missense	proximal	-1	no	3.225	4.168	EPSD	COSMIC	2.840	Up-regulation
AGC_Akt_AKT3_ST	P15056	BRAF	Q9Y243	AKT3	S335	P341T	341	Missense	distal	6	no	3.225	3.222	EPSD	COSMIC	2.840	Down-regulation
AGC_Akt_AKT3_ST	P15056	BRAF	Q9Y243	AKT3	S335	S339F	339	Missense	distal	4	no	3.225	3.127	EPSD	COSMIC	2.840	Down-regulation
AGC_Akt_AKT3_ST	P15056	BRAF	Q9Y243	AKT3	S335	P341S	341	Missense	distal	6	no	3.225	3.201	EPSD	COSMIC	2.840	Down-regulation
AGC_Akt_AKT3_ST	P15056	BRAF	Q9Y243	AKT3	S335	S337L	337	Missense	proximal	2	no	3.225	3.696	EPSD	COSMIC	2.840	Up-regulation
AGC_Akt_AKT3_ST	P15056	BRAF	Q9Y243	AKT3	S335	S337P	337	Missense	proximal	2	no	3.225	3.551	EPSD	COSMIC	2.840	Up-regulation
AGC_Akt_AKT3_ST	P15056	BRAF	Q9Y243	AKT3	S339	P334S	334	Missense	distal	-5	no	2.797	2.850	EPSD	COSMIC	2.840	Gain
AGC_Akt_AKT3_ST	P15056	BRAF	Q9Y243	AKT3	S363	S365L	365	Missense	proximal	2	no	2.533	3.004	EPSD	COSMIC	2.840	Gain
AGC_Akt_AKT3_ST	P15056	BRAF	Q9Y243	AKT3	S365	R360Q	360	Missense	distal	-5	no	9.586	8.399	PhosphoSitePlus;EPSD	COSMIC	2.840	Down-regulation
AGC_Akt_AKT3_ST	P15056	BRAF	Q9Y243	AKT3	S365	S365L	365	Missense	central	0	yes	9.586	0.000	PhosphoSitePlus;EPSD	COSMIC	2.840	Loss
AGC_Akt_AKT3_ST	P15056	BRAF	Q9Y243	AKT3	S365	R362L	362	Missense	distal	-3	no	9.586	7.053	PhosphoSitePlus;EPSD	COSMIC	2.840	Down-regulation
AGC_Akt_AKT3_ST	P15056	BRAF	Q9Y243	AKT3	T411	P407L	407	Missense	distal	-4	no	2.951	2.898	EPSD	COSMIC	2.840	Down-regulation
AGC_Akt_AKT3_ST	P15056	BRAF	Q9Y243	AKT3	T411	A404V	404	Missense	distal	-7	no	2.951	2.781	EPSD	COSMIC	2.840	Loss
AGC_Akt_AKT3_ST	P15056	BRAF	Q9Y243	AKT3	T411	V413M	413	Missense	proximal	2	no	2.951	3.059	EPSD	COSMIC	2.840	Up-regulation
AGC_Akt_AKT3_ST	P15056	BRAF	Q9Y243	AKT3	T411	N412S	412	Missense	proximal	1	no	2.951	2.922	EPSD	COSMIC	2.840	Down-regulation
AGC_Akt_AKT3_ST	P15056	BRAF	Q9Y243	AKT3	T411	L416S	416	Missense	distal	5	no	2.951	2.850	EPSD	COSMIC	2.840	Down-regulation
AGC_Akt_AKT3_ST	P15056	BRAF	Q9Y243	AKT3	S429	P422A	422	Missense	distal	-7	no	8.364	8.508	EPSD;PhosphoSitePlus	COSMIC	2.840	Up-regulation
AGC_Akt_AKT3_ST	P15056	BRAF	Q9Y243	AKT3	S429	S428L	428	Missense	proximal	-1	no	8.364	7.398	EPSD;PhosphoSitePlus	COSMIC	2.840	Down-regulation
AGC_Akt_AKT3_ST	P15056	BRAF	Q9Y243	AKT3	S429	R424L	424	Missense	distal	-5	no	8.364	7.143	EPSD;PhosphoSitePlus	COSMIC	2.840	Down-regulation
AGC_Akt_AKT3_ST	P15056	BRAF	Q9Y243	AKT3	S431	S428L	428	Missense	distal	-3	no	4.867	4.957	EPSD	COSMIC	2.840	Up-regulation
AGC_Akt_AKT3_ST	P15056	BRAF	Q9Y243	AKT3	S431	R424L	424	Missense	distal	-7	no	4.867	4.730	EPSD	COSMIC	2.840	Down-regulation
AGC_Akt_AKT3_ST	P15056	BRAF	Q9Y243	AKT3	T440	S447N	447	Missense	distal	7	no	3.952	4.002	EPSD	COSMIC	2.840	Up-regulation
AGC_Akt_AKT3_ST	P15056	BRAF	Q9Y243	AKT3	T440	R443I	443	Missense	distal	3	no	3.952	3.839	EPSD	COSMIC	2.840	Down-regulation
AGC_Akt_AKT3_ST	P15056	BRAF	Q9Y243	AKT3	T440	R443T	443	Missense	distal	3	no	3.952	3.950	EPSD	COSMIC	2.840	Down-regulation
AGC_Akt_AKT3_ST	P15056	BRAF	Q9Y243	AKT3	T440	K439T	439	Missense	proximal	-1	no	3.952	4.277	EPSD	COSMIC	2.840	Up-regulation
AGC_Akt_AKT3_ST	P15056	BRAF	Q9Y243	AKT3	T440	G442S	442	Missense	proximal	2	no	3.952	3.901	EPSD	COSMIC	2.840	Down-regulation
AGC_Akt_AKT3_ST	P15056	BRAF	Q9Y243	AKT3	T440	T440P	440	Missense	central	0	yes	3.952	0.000	EPSD	COSMIC	2.840	Loss
AGC_Akt_AKT3_ST	P15056	BRAF	Q9Y243	AKT3	T440	L441V	441	Missense	proximal	1	no	3.952	3.943	EPSD	COSMIC	2.840	Down-regulation
AGC_Akt_AKT3_ST	P15056	BRAF	Q9Y243	AKT3	T440	K439Q	439	Missense	proximal	-1	no	3.952	3.501	EPSD	COSMIC	2.840	Down-regulation
AGC_Akt_AKT3_ST	P15056	BRAF	Q9Y243	AKT3	T440	S447C	447	Missense	distal	7	no	3.952	3.815	EPSD	COSMIC	2.840	Down-regulation
AGC_Akt_AKT3_ST	P15056	BRAF	Q9Y243	AKT3	T440	G442D	442	Missense	proximal	2	no	3.952	4.011	EPSD	COSMIC	2.840	Up-regulation
AGC_Akt_AKT3_ST	P15056	BRAF	Q9Y243	AKT3	T440	T440I	440	Missense	central	0	yes	3.952	0.000	EPSD	COSMIC	2.840	Loss
AGC_Akt_AKT3_ST	P15056	BRAF	Q9Y243	AKT3	S446	S447N	447	Missense	proximal	1	no	4.270	4.300	EPSD	COSMIC	2.840	Up-regulation
AGC_Akt_AKT3_ST	P15056	BRAF	Q9Y243	AKT3	S446	P453H	453	Missense	distal	7	no	4.270	4.097	EPSD	COSMIC	2.840	Down-regulation
AGC_Akt_AKT3_ST	P15056	BRAF	Q9Y243	AKT3	S446	P453T	453	Missense	distal	7	no	4.270	4.077	EPSD	COSMIC	2.840	Down-regulation
AGC_Akt_AKT3_ST	P15056	BRAF	Q9Y243	AKT3	S446	R443I	443	Missense	distal	-3	no	4.270	1.621	EPSD	COSMIC	2.840	Loss
AGC_Akt_AKT3_ST	P15056	BRAF	Q9Y243	AKT3	S446	W450L	450	Missense	distal	4	no	4.270	4.182	EPSD	COSMIC	2.840	Down-regulation
AGC_Akt_AKT3_ST	P15056	BRAF	Q9Y243	AKT3	S446	R443T	443	Missense	distal	-3	no	4.270	1.787	EPSD	COSMIC	2.840	Loss
AGC_Akt_AKT3_ST	P15056	BRAF	Q9Y243	AKT3	S446	K439T	439	Missense	distal	-7	no	4.270	4.335	EPSD	COSMIC	2.840	Up-regulation
AGC_Akt_AKT3_ST	P15056	BRAF	Q9Y243	AKT3	S446	G442S	442	Missense	distal	-4	no	4.270	4.274	EPSD	COSMIC	2.840	Up-regulation
AGC_Akt_AKT3_ST	P15056	BRAF	Q9Y243	AKT3	S446	T440P	440	Missense	distal	-6	no	4.270	4.249	EPSD	COSMIC	2.840	Down-regulation
AGC_Akt_AKT3_ST	P15056	BRAF	Q9Y243	AKT3	S446	L441V	441	Missense	distal	-5	no	4.270	3.995	EPSD	COSMIC	2.840	Down-regulation
AGC_Akt_AKT3_ST	P15056	BRAF	Q9Y243	AKT3	S446	K439Q	439	Missense	distal	-7	no	4.270	4.178	EPSD	COSMIC	2.840	Down-regulation
AGC_Akt_AKT3_ST	P15056	BRAF	Q9Y243	AKT3	S446	S447C	447	Missense	proximal	1	no	4.270	4.294	EPSD	COSMIC	2.840	Up-regulation
AGC_Akt_AKT3_ST	P15056	BRAF	Q9Y243	AKT3	S446	D449E	449	Missense	distal	3	no	4.270	4.295	EPSD	COSMIC	2.840	Up-regulation
AGC_Akt_AKT3_ST	P15056	BRAF	Q9Y243	AKT3	S446	G442D	442	Missense	distal	-4	no	4.270	4.278	EPSD	COSMIC	2.840	Up-regulation
AGC_Akt_AKT3_ST	P15056	BRAF	Q9Y243	AKT3	S446	T440I	440	Missense	distal	-6	no	4.270	4.229	EPSD	COSMIC	2.840	Down-regulation
AGC_Akt_AKT3_ST	P15056	BRAF	Q9Y243	AKT3	S446	W450R	450	Missense	distal	4	no	4.270	4.228	EPSD	COSMIC	2.840	Down-regulation
AGC_Akt_AKT3_ST	P15056	BRAF	Q9Y243	AKT3	S446	D449Y	449	Missense	distal	3	no	4.270	4.316	EPSD	COSMIC	2.840	Up-regulation
AGC_Akt_AKT3_ST	P15056	BRAF	Q9Y243	AKT3	S447	S447N	447	Missense	central	0	yes	5.637	0.000	EPSD	COSMIC	2.840	Loss
AGC_Akt_AKT3_ST	P15056	BRAF	Q9Y243	AKT3	S447	P453H	453	Missense	distal	6	no	5.637	5.631	EPSD	COSMIC	2.840	Down-regulation
AGC_Akt_AKT3_ST	P15056	BRAF	Q9Y243	AKT3	S447	P453T	453	Missense	distal	6	no	5.637	5.634	EPSD	COSMIC	2.840	Down-regulation
AGC_Akt_AKT3_ST	P15056	BRAF	Q9Y243	AKT3	S447	R443I	443	Missense	distal	-4	no	5.637	5.607	EPSD	COSMIC	2.840	Down-regulation
AGC_Akt_AKT3_ST	P15056	BRAF	Q9Y243	AKT3	S447	W450L	450	Missense	distal	3	no	5.637	5.517	EPSD	COSMIC	2.840	Down-regulation
AGC_Akt_AKT3_ST	P15056	BRAF	Q9Y243	AKT3	S447	R443T	443	Missense	distal	-4	no	5.637	5.636	EPSD	COSMIC	2.840	Down-regulation
AGC_Akt_AKT3_ST	P15056	BRAF	Q9Y243	AKT3	S447	G442S	442	Missense	distal	-5	no	5.637	5.720	EPSD	COSMIC	2.840	Up-regulation
AGC_Akt_AKT3_ST	P15056	BRAF	Q9Y243	AKT3	S447	T440P	440	Missense	distal	-7	no	5.637	5.491	EPSD	COSMIC	2.840	Down-regulation
AGC_Akt_AKT3_ST	P15056	BRAF	Q9Y243	AKT3	S447	D454N	454	Missense	distal	7	no	5.637	5.807	EPSD	COSMIC	2.840	Up-regulation
AGC_Akt_AKT3_ST	P15056	BRAF	Q9Y243	AKT3	S447	L441V	441	Missense	distal	-6	no	5.637	5.799	EPSD	COSMIC	2.840	Up-regulation
AGC_Akt_AKT3_ST	P15056	BRAF	Q9Y243	AKT3	S447	S447C	447	Missense	central	0	yes	5.637	0.000	EPSD	COSMIC	2.840	Loss
AGC_Akt_AKT3_ST	P15056	BRAF	Q9Y243	AKT3	S447	D449E	449	Missense	proximal	2	no	5.637	5.803	EPSD	COSMIC	2.840	Up-regulation
AGC_Akt_AKT3_ST	P15056	BRAF	Q9Y243	AKT3	S447	G442D	442	Missense	distal	-5	no	5.637	5.754	EPSD	COSMIC	2.840	Up-regulation
AGC_Akt_AKT3_ST	P15056	BRAF	Q9Y243	AKT3	S447	T440I	440	Missense	distal	-7	no	5.637	5.430	EPSD	COSMIC	2.840	Down-regulation
AGC_Akt_AKT3_ST	P15056	BRAF	Q9Y243	AKT3	S447	W450R	450	Missense	distal	3	no	5.637	5.817	EPSD	COSMIC	2.840	Up-regulation
AGC_Akt_AKT3_ST	P15056	BRAF	Q9Y243	AKT3	S447	D449Y	449	Missense	proximal	2	no	5.637	5.617	EPSD	COSMIC	2.840	Down-regulation
AGC_Akt_AKT3_ST	P15056	BRAF	Q9Y243	AKT3	T458	G455R	455	Missense	distal	-3	no	1.118	3.772	EPSD	COSMIC	2.840	Gain
AGC_Akt_AKT3_ST	P15056	BRAF	Q9Y243	AKT3	S465	Y472S	472	Missense	distal	7	no	2.664	2.842	EPSD	COSMIC	2.840	Gain
AGC_Akt_AKT3_ST	P15056	BRAF	Q9Y243	AKT3	S465	T470I	470	Missense	distal	5	no	2.664	2.899	EPSD	COSMIC	2.840	Gain
AGC_Akt_AKT3_ST	P15056	BRAF	Q9Y243	AKT3	S465	G460R	460	Missense	distal	-5	no	2.664	3.997	EPSD	COSMIC	2.840	Gain
AGC_Akt_AKT3_ST	P15056	BRAF	Q9Y243	AKT3	S465	I463S	463	Missense	proximal	-2	no	2.664	3.657	EPSD	COSMIC	2.840	Gain
AGC_Akt_AKT3_ST	P15056	BRAF	Q9Y243	AKT3	S467	G464R	464	Missense	distal	-3	no	2.337	4.992	EPSD	COSMIC	2.840	Gain
AGC_Akt_AKT3_ST	P15056	BRAF	Q9Y243	AKT3	T599	L597S	597	Missense	proximal	-2	no	1.983	2.923	EPSD	COSMIC	2.840	Gain
AGC_Akt_AKT3_ST	P15056	BRAF	Q9Y243	AKT3	S602	T599R	599	Missense	distal	-3	no	1.233	3.717	EPSD	COSMIC	2.840	Gain
AGC_Akt_AKT3_ST	P15056	BRAF	Q9Y243	AKT3	S607	W604R	604	Missense	distal	-3	no	1.267	3.933	EPSD	COSMIC	2.840	Gain
AGC_Akt_AKT3_ST	P15056	BRAF	Q9Y243	AKT3	S614	Q609R	609	Missense	distal	-5	no	1.720	2.906	EPSD	COSMIC	2.840	Gain
AGC_Akt_AKT3_ST	P15056	BRAF	Q9Y243	AKT3	S720	E715K	715	Missense	distal	-5	no	2.636	3.138	EPSD	COSMIC	2.840	Gain
AGC_Akt_AKT3_ST	P15056	BRAF	Q9Y243	AKT3	S729	S732F	732	Missense	distal	3	no	4.901	4.784	EPSD	COSMIC	2.840	Down-regulation
AGC_Akt_AKT3_ST	P15056	BRAF	Q9Y243	AKT3	S729	A728D	728	Missense	proximal	-1	no	4.901	4.239	EPSD	COSMIC	2.840	Down-regulation
AGC_Akt_AKT3_ST	P15056	BRAF	Q9Y243	AKT3	S729	S727T	727	Missense	proximal	-2	no	4.901	4.587	EPSD	COSMIC	2.840	Down-regulation
AGC_Akt_AKT3_ST	P15056	BRAF	Q9Y243	AKT3	S729	H725Q	725	Missense	distal	-4	no	4.901	4.916	EPSD	COSMIC	2.840	Up-regulation
AGC_Akt_AKT3_ST	Q7Z589	EMSY	Q9Y243	AKT3	T115	V114A	114	Missense	proximal	-1	no	2.197	2.945	EPSD	COSMIC	2.840	Gain
AGC_Akt_AKT3_ST	Q7Z589	EMSY	Q9Y243	AKT3	S129	H126R	126	Missense	distal	-3	no	0.538	2.851	EPSD	COSMIC	2.840	Gain
AGC_Akt_AKT3_ST	Q7Z589	EMSY	Q9Y243	AKT3	S173	P169S	169	Missense	distal	-4	no	3.048	3.045	EPSD	COSMIC	2.840	Down-regulation
AGC_Akt_AKT3_ST	Q7Z589	EMSY	Q9Y243	AKT3	S173	A172T	172	Missense	proximal	-1	no	3.048	2.905	EPSD	COSMIC	2.840	Down-regulation
AGC_Akt_AKT3_ST	Q7Z589	EMSY	Q9Y243	AKT3	S173	N177D	177	Missense	distal	4	no	3.048	3.117	EPSD	COSMIC	2.840	Up-regulation
AGC_Akt_AKT3_ST	Q7Z589	EMSY	Q9Y243	AKT3	S173	R170S	170	Missense	distal	-3	no	3.048	0.425	EPSD	COSMIC	2.840	Loss
AGC_Akt_AKT3_ST	Q7Z589	EMSY	Q9Y243	AKT3	S173	P171S	171	Missense	proximal	-2	no	3.048	3.993	EPSD	COSMIC	2.840	Up-regulation
AGC_Akt_AKT3_ST	Q7Z589	EMSY	Q9Y243	AKT3	S173	V166I	166	Missense	distal	-7	no	3.048	3.013	EPSD	COSMIC	2.840	Down-regulation
AGC_Akt_AKT3_ST	Q7Z589	EMSY	Q9Y243	AKT3	S173	P171L	171	Missense	proximal	-2	no	3.048	3.053	EPSD	COSMIC	2.840	Up-regulation
AGC_Akt_AKT3_ST	Q7Z589	EMSY	Q9Y243	AKT3	S173	P174S	174	Missense	proximal	1	no	3.048	3.018	EPSD	COSMIC	2.840	Down-regulation
AGC_Akt_AKT3_ST	Q7Z589	EMSY	Q9Y243	AKT3	S173	V180I	180	Missense	distal	7	no	3.048	2.976	EPSD	COSMIC	2.840	Down-regulation
AGC_Akt_AKT3_ST	Q7Z589	EMSY	Q9Y243	AKT3	S173	S176C	176	Missense	distal	3	no	3.048	2.980	EPSD	COSMIC	2.840	Down-regulation
AGC_Akt_AKT3_ST	Q7Z589	EMSY	Q9Y243	AKT3	S176	P174S	174	Missense	proximal	-2	no	1.929	2.874	EPSD	COSMIC	2.840	Gain
AGC_Akt_AKT3_ST	Q7Z589	EMSY	Q9Y243	AKT3	T207	S211F	211	Missense	distal	4	no	4.707	4.609	PhosphoSitePlus;EPSD	COSMIC	2.840	Down-regulation
AGC_Akt_AKT3_ST	Q7Z589	EMSY	Q9Y243	AKT3	T207	S210F	210	Missense	distal	3	no	4.707	4.590	PhosphoSitePlus;EPSD	COSMIC	2.840	Down-regulation
AGC_Akt_AKT3_ST	Q7Z589	EMSY	Q9Y243	AKT3	T207	S212I	212	Missense	distal	5	no	4.707	4.838	PhosphoSitePlus;EPSD	COSMIC	2.840	Up-regulation
AGC_Akt_AKT3_ST	Q7Z589	EMSY	Q9Y243	AKT3	T207	S209F	209	Missense	proximal	2	no	4.707	4.833	PhosphoSitePlus;EPSD	COSMIC	2.840	Up-regulation
AGC_Akt_AKT3_ST	Q7Z589	EMSY	Q9Y243	AKT3	T207	S211I	211	Missense	distal	4	no	4.707	4.597	PhosphoSitePlus;EPSD	COSMIC	2.840	Down-regulation
AGC_Akt_AKT3_ST	Q7Z589	EMSY	Q9Y243	AKT3	T207	K203R	203	Missense	distal	-4	no	4.707	4.714	PhosphoSitePlus;EPSD	COSMIC	2.840	Up-regulation
AGC_Akt_AKT3_ST	Q7Z589	EMSY	Q9Y243	AKT3	T207	R206Q	206	Missense	proximal	-1	no	4.707	4.649	PhosphoSitePlus;EPSD	COSMIC	2.840	Down-regulation
AGC_Akt_AKT3_ST	Q7Z589	EMSY	Q9Y243	AKT3	T207	S213C	213	Missense	distal	6	no	4.707	4.715	PhosphoSitePlus;EPSD	COSMIC	2.840	Up-regulation
AGC_Akt_AKT3_ST	Q7Z589	EMSY	Q9Y243	AKT3	S209	S211F	211	Missense	proximal	2	no	4.066	4.193	EPSD;PhosphoSitePlus	COSMIC	2.840	Up-regulation
AGC_Akt_AKT3_ST	Q7Z589	EMSY	Q9Y243	AKT3	S209	S210F	210	Missense	proximal	1	no	4.066	4.098	EPSD;PhosphoSitePlus	COSMIC	2.840	Up-regulation
AGC_Akt_AKT3_ST	Q7Z589	EMSY	Q9Y243	AKT3	S209	S212I	212	Missense	distal	3	no	4.066	4.005	EPSD;PhosphoSitePlus	COSMIC	2.840	Down-regulation
AGC_Akt_AKT3_ST	Q7Z589	EMSY	Q9Y243	AKT3	S209	S209F	209	Missense	central	0	yes	4.066	0.000	EPSD;PhosphoSitePlus	COSMIC	2.840	Loss
AGC_Akt_AKT3_ST	Q7Z589	EMSY	Q9Y243	AKT3	S209	S211I	211	Missense	proximal	2	no	4.066	4.373	EPSD;PhosphoSitePlus	COSMIC	2.840	Up-regulation
AGC_Akt_AKT3_ST	Q7Z589	EMSY	Q9Y243	AKT3	S209	K203R	203	Missense	distal	-6	no	4.066	4.111	EPSD;PhosphoSitePlus	COSMIC	2.840	Up-regulation
AGC_Akt_AKT3_ST	Q7Z589	EMSY	Q9Y243	AKT3	S209	R206Q	206	Missense	distal	-3	no	4.066	1.861	EPSD;PhosphoSitePlus	COSMIC	2.840	Loss
AGC_Akt_AKT3_ST	Q7Z589	EMSY	Q9Y243	AKT3	S209	S213C	213	Missense	distal	4	no	4.066	3.953	EPSD;PhosphoSitePlus	COSMIC	2.840	Down-regulation
AGC_Akt_AKT3_ST	Q7Z589	EMSY	Q9Y243	AKT3	S210	S211F	211	Missense	proximal	1	no	3.689	3.721	EPSD	COSMIC	2.840	Up-regulation
AGC_Akt_AKT3_ST	Q7Z589	EMSY	Q9Y243	AKT3	S210	S210F	210	Missense	central	0	yes	3.689	0.000	EPSD	COSMIC	2.840	Loss
AGC_Akt_AKT3_ST	Q7Z589	EMSY	Q9Y243	AKT3	S210	S212I	212	Missense	proximal	2	no	3.689	3.996	EPSD	COSMIC	2.840	Up-regulation
AGC_Akt_AKT3_ST	Q7Z589	EMSY	Q9Y243	AKT3	S210	S209F	209	Missense	proximal	-1	no	3.689	2.694	EPSD	COSMIC	2.840	Loss
AGC_Akt_AKT3_ST	Q7Z589	EMSY	Q9Y243	AKT3	S210	S211I	211	Missense	proximal	1	no	3.689	3.718	EPSD	COSMIC	2.840	Up-regulation
AGC_Akt_AKT3_ST	Q7Z589	EMSY	Q9Y243	AKT3	S210	K203R	203	Missense	distal	-7	no	3.689	3.700	EPSD	COSMIC	2.840	Up-regulation
AGC_Akt_AKT3_ST	Q7Z589	EMSY	Q9Y243	AKT3	S210	R206Q	206	Missense	distal	-4	no	3.689	3.674	EPSD	COSMIC	2.840	Down-regulation
AGC_Akt_AKT3_ST	Q7Z589	EMSY	Q9Y243	AKT3	S210	S213C	213	Missense	distal	3	no	3.689	3.621	EPSD	COSMIC	2.840	Down-regulation
AGC_Akt_AKT3_ST	Q7Z589	EMSY	Q9Y243	AKT3	S211	S211F	211	Missense	central	0	yes	4.644	0.000	EPSD	COSMIC	2.840	Loss
AGC_Akt_AKT3_ST	Q7Z589	EMSY	Q9Y243	AKT3	S211	S210F	210	Missense	proximal	-1	no	4.644	3.650	EPSD	COSMIC	2.840	Down-regulation
AGC_Akt_AKT3_ST	Q7Z589	EMSY	Q9Y243	AKT3	S211	S212I	212	Missense	proximal	1	no	4.644	4.674	EPSD	COSMIC	2.840	Up-regulation
AGC_Akt_AKT3_ST	Q7Z589	EMSY	Q9Y243	AKT3	S211	K218R	218	Missense	distal	7	no	4.644	4.632	EPSD	COSMIC	2.840	Down-regulation
AGC_Akt_AKT3_ST	Q7Z589	EMSY	Q9Y243	AKT3	S211	S209F	209	Missense	proximal	-2	no	4.644	3.673	EPSD	COSMIC	2.840	Down-regulation
AGC_Akt_AKT3_ST	Q7Z589	EMSY	Q9Y243	AKT3	S211	S211I	211	Missense	central	0	yes	4.644	0.000	EPSD	COSMIC	2.840	Loss
AGC_Akt_AKT3_ST	Q7Z589	EMSY	Q9Y243	AKT3	S211	R206Q	206	Missense	distal	-5	no	4.644	3.458	EPSD	COSMIC	2.840	Down-regulation
AGC_Akt_AKT3_ST	Q7Z589	EMSY	Q9Y243	AKT3	S211	S213C	213	Missense	proximal	2	no	4.644	4.851	EPSD	COSMIC	2.840	Up-regulation
AGC_Akt_AKT3_ST	Q7Z589	EMSY	Q9Y243	AKT3	T315	P320S	320	Missense	distal	5	no	2.814	2.896	EPSD	COSMIC	2.840	Gain
AGC_Akt_AKT3_ST	Q7Z589	EMSY	Q9Y243	AKT3	T315	P319S	319	Missense	distal	4	no	2.814	2.901	EPSD	COSMIC	2.840	Gain
AGC_Akt_AKT3_ST	Q7Z589	EMSY	Q9Y243	AKT3	T506	G505S	505	Missense	proximal	-1	no	2.095	3.034	EPSD	COSMIC	2.840	Gain
AGC_Akt_AKT3_ST	Q7Z589	EMSY	Q9Y243	AKT3	T530	T530A	530	Missense	central	0	yes	3.734	0.000	EPSD	COSMIC	2.840	Loss
AGC_Akt_AKT3_ST	Q7Z589	EMSY	Q9Y243	AKT3	T530	A523V	523	Missense	distal	-7	no	3.734	3.565	EPSD	COSMIC	2.840	Down-regulation
AGC_Akt_AKT3_ST	Q7Z589	EMSY	Q9Y243	AKT3	T530	A529T	529	Missense	proximal	-1	no	3.734	3.591	EPSD	COSMIC	2.840	Down-regulation
AGC_Akt_AKT3_ST	Q7Z589	EMSY	Q9Y243	AKT3	T530	A524V	524	Missense	distal	-6	no	3.734	3.790	EPSD	COSMIC	2.840	Up-regulation
AGC_Akt_AKT3_ST	Q7Z589	EMSY	Q9Y243	AKT3	S705	E700K	700	Missense	distal	-5	no	2.568	3.071	EPSD	COSMIC	2.840	Gain
AGC_Akt_AKT3_ST	Q7Z589	EMSY	Q9Y243	AKT3	S1136	T1133R	1133	Missense	distal	-3	no	1.710	4.193	EPSD	COSMIC	2.840	Gain
AGC_Akt_AKT3_ST	Q7Z589	EMSY	Q9Y243	AKT3	S1213	C1207G	1207	Missense	distal	-6	no	2.779	2.864	EPSD	COSMIC	2.840	Gain
STE_STE11_MEKK1_MAP3K1_ST	O14733	MAP2K7	Q13233	MAP3K1	S265	L259R	259	Missense	distal	-6	no	2.426	2.459	EPSD	COSMIC	2.285	Up-regulation
STE_STE11_MEKK1_MAP3K1_ST	O14733	MAP2K7	Q13233	MAP3K1	S265	S271T	271	Missense	distal	6	no	2.426	2.025	EPSD	COSMIC	2.285	Loss
STE_STE11_MEKK1_MAP3K1_ST	O14733	MAP2K7	Q13233	MAP3K1	S265	G263S	263	Missense	proximal	-2	no	2.426	2.701	EPSD	COSMIC	2.285	Up-regulation
STE_STE11_MEKK1_MAP3K1_ST	O14733	MAP2K7	Q13233	MAP3K1	S265	S271C	271	Missense	distal	6	no	2.426	1.924	EPSD	COSMIC;GDSC;CCLE	2.285	Loss
STE_STE11_MEKK1_MAP3K1_ST	O14733	MAP2K7	Q13233	MAP3K1	S271	A278T	278	Missense	distal	7	no	4.764	4.768	PhosphoSitePlus;EPSD	COSMIC	2.285	Up-regulation
STE_STE11_MEKK1_MAP3K1_ST	O14733	MAP2K7	Q13233	MAP3K1	S271	S277C	277	Missense	distal	6	no	4.764	4.262	PhosphoSitePlus;EPSD	COSMIC	2.285	Down-regulation
STE_STE11_MEKK1_MAP3K1_ST	O14733	MAP2K7	Q13233	MAP3K1	S271	T275A	275	Missense	distal	4	no	4.764	4.419	PhosphoSitePlus;EPSD	COSMIC	2.285	Down-regulation
STE_STE11_MEKK1_MAP3K1_ST	O14733	MAP2K7	Q13233	MAP3K1	S271	R276W	276	Missense	distal	5	no	4.764	4.857	PhosphoSitePlus;EPSD	COSMIC	2.285	Up-regulation
STE_STE11_MEKK1_MAP3K1_ST	O14733	MAP2K7	Q13233	MAP3K1	S271	S271C	271	Missense	central	0	yes	4.764	0.000	PhosphoSitePlus;EPSD	COSMIC;GDSC;CCLE	2.285	Loss
STE_STE11_MEKK1_MAP3K1_ST	O14733	MAP2K7	Q13233	MAP3K1	T275	A282T	282	Missense	distal	7	no	4.996	5.000	EPSD;PhosphoSitePlus	COSMIC	2.285	Up-regulation
STE_STE11_MEKK1_MAP3K1_ST	O14733	MAP2K7	Q13233	MAP3K1	T275	A278T	278	Missense	distal	3	no	4.996	5.001	EPSD;PhosphoSitePlus	COSMIC	2.285	Up-regulation
STE_STE11_MEKK1_MAP3K1_ST	O14733	MAP2K7	Q13233	MAP3K1	T275	S277C	277	Missense	proximal	2	no	4.996	3.586	EPSD;PhosphoSitePlus	COSMIC	2.285	Down-regulation
STE_STE11_MEKK1_MAP3K1_ST	O14733	MAP2K7	Q13233	MAP3K1	T275	T275A	275	Missense	central	0	yes	4.996	0.000	EPSD;PhosphoSitePlus	COSMIC	2.285	Loss
STE_STE11_MEKK1_MAP3K1_ST	O14733	MAP2K7	Q13233	MAP3K1	T275	S271T	271	Missense	distal	-4	no	4.996	4.410	EPSD;PhosphoSitePlus	COSMIC	2.285	Down-regulation
STE_STE11_MEKK1_MAP3K1_ST	O14733	MAP2K7	Q13233	MAP3K1	T275	R276W	276	Missense	proximal	1	no	4.996	4.893	EPSD;PhosphoSitePlus	COSMIC	2.285	Down-regulation
STE_STE11_MEKK1_MAP3K1_ST	O14733	MAP2K7	Q13233	MAP3K1	T275	S271C	271	Missense	distal	-4	no	4.996	4.294	EPSD;PhosphoSitePlus	COSMIC;GDSC;CCLE	2.285	Down-regulation
STE_STE11_MEKK1_MAP3K1_ST	P46531	NOTCH1	Q13233	MAP3K1	S900	C895W	895	Missense	distal	-5	no	2.321	2.307	EPSD	COSMIC	2.285	Down-regulation
STE_STE11_MEKK1_MAP3K1_ST	P46531	NOTCH1	Q13233	MAP3K1	S900	G898S	898	Missense	proximal	-2	no	2.321	2.596	EPSD	COSMIC	2.285	Up-regulation
STE_STE11_MEKK1_MAP3K1_ST	P46531	NOTCH1	Q13233	MAP3K1	S900	R902H	902	Missense	proximal	2	no	2.321	1.689	EPSD	COSMIC	2.285	Loss
STE_STE11_MEKK1_MAP3K1_ST	P46531	NOTCH1	Q13233	MAP3K1	S900	C904W	904	Missense	distal	4	no	2.321	2.387	EPSD	COSMIC	2.285	Up-regulation
STE_STE11_MEKK1_MAP3K1_ST	P46531	NOTCH1	Q13233	MAP3K1	S900	G901V	901	Missense	proximal	1	no	2.321	2.266	EPSD	COSMIC	2.285	Loss
STE_STE11_MEKK1_MAP3K1_ST	P46531	NOTCH1	Q13233	MAP3K1	T1930	E1929D	1929	Missense	proximal	-1	no	2.233	2.300	EPSD	COSMIC	2.285	Gain
STE_STE11_MEKK1_MAP3K1_ST	P46531	NOTCH1	Q13233	MAP3K1	T1930	E1929K	1929	Missense	proximal	-1	no	2.233	2.298	EPSD	COSMIC	2.285	Gain
STE_STE11_MEKK1_MAP3K1_ST	P46531	NOTCH1	Q13233	MAP3K1	T1930	G1928S	1928	Missense	proximal	-2	no	2.233	2.508	EPSD	COSMIC	2.285	Gain
STE_STE11_MEKK1_MAP3K1_ST	P46531	NOTCH1	Q13233	MAP3K1	S1939	A1943V	1943	Missense	distal	4	no	2.355	2.330	EPSD	COSMIC	2.285	Down-regulation
STE_STE11_MEKK1_MAP3K1_ST	P46531	NOTCH1	Q13233	MAP3K1	S1939	A1944T	1944	Missense	distal	5	no	2.355	2.385	EPSD	COSMIC;CCLE	2.285	Up-regulation
STE_STE11_MEKK1_MAP3K1_ST	P46531	NOTCH1	Q13233	MAP3K1	S1939	R1937C	1937	Missense	proximal	-2	no	2.355	2.118	EPSD	COSMIC	2.285	Loss
STE_STE11_MEKK1_MAP3K1_ST	P46531	NOTCH1	Q13233	MAP3K1	S1939	S1941F	1941	Missense	proximal	2	no	2.355	1.203	EPSD	COSMIC	2.285	Loss
STE_STE11_MEKK1_MAP3K1_ST	P46531	NOTCH1	Q13233	MAP3K1	S1939	R1940C	1940	Missense	proximal	1	no	2.355	2.150	EPSD	COSMIC	2.285	Loss
STE_STE11_MEKK1_MAP3K1_ST	P46531	NOTCH1	Q13233	MAP3K1	S1939	A1935V	1935	Missense	distal	-4	no	2.355	1.857	EPSD	COSMIC	2.285	Loss
STE_STE11_MEKK1_MAP3K1_ST	P46531	NOTCH1	Q13233	MAP3K1	T1997	A2002V	2002	Missense	distal	5	no	2.767	2.794	EPSD	COSMIC	2.285	Up-regulation
STE_STE11_MEKK1_MAP3K1_ST	P46531	NOTCH1	Q13233	MAP3K1	T1997	R2004H	2004	Missense	distal	7	no	2.767	2.769	EPSD	COSMIC	2.285	Up-regulation
STE_STE11_MEKK1_MAP3K1_ST	P46531	NOTCH1	Q13233	MAP3K1	T2132	P2133A	2133	Missense	proximal	1	no	2.608	2.169	EPSD	COSMIC	2.285	Loss
STE_STE11_MEKK1_MAP3K1_ST	P46531	NOTCH1	Q13233	MAP3K1	T2132	L2139F	2139	Missense	distal	7	no	2.608	2.607	EPSD	COSMIC	2.285	Down-regulation
STE_STE11_MEKK1_MAP3K1_ST	P46531	NOTCH1	Q13233	MAP3K1	T2132	G2131N	2131	Missense	proximal	-1	no	2.608	2.636	EPSD	COSMIC	2.285	Up-regulation
STE_STE11_MEKK1_MAP3K1_ST	P46531	NOTCH1	Q13233	MAP3K1	T2132	T2132M	2132	Missense	central	0	yes	2.608	0.000	EPSD	COSMIC	2.285	Loss
STE_STE11_MEKK1_MAP3K1_ST	P46531	NOTCH1	Q13233	MAP3K1	T2132	L2139P	2139	Missense	distal	7	no	2.608	2.604	EPSD	COSMIC	2.285	Down-regulation
STE_STE11_MEKK1_MAP3K1_ST	P46531	NOTCH1	Q13233	MAP3K1	T2132	L2129V	2129	Missense	distal	-3	no	2.608	2.845	EPSD	COSMIC	2.285	Up-regulation
STE_STE11_MEKK1_MAP3K1_ST	P46531	NOTCH1	Q13233	MAP3K1	S2215	D2212N	2212	Missense	distal	-3	no	2.244	2.527	EPSD	COSMIC	2.285	Gain
STE_STE11_MEKK1_MAP3K1_ST	P46531	NOTCH1	Q13233	MAP3K1	T2511	P2514R	2514	Missense	distal	3	no	4.557	4.576	PhosphoSitePlus	COSMIC	2.285	Up-regulation
STE_STE11_MEKK1_MAP3K1_ST	P46531	NOTCH1	Q13233	MAP3K1	T2511	P2517L	2517	Missense	distal	6	no	4.557	4.214	PhosphoSitePlus	COSMIC	2.285	Down-regulation
STE_STE11_MEKK1_MAP3K1_ST	P46531	NOTCH1	Q13233	MAP3K1	T2511	H2507R	2507	Missense	distal	-4	no	4.557	4.598	PhosphoSitePlus	COSMIC	2.285	Up-regulation
STE_STE11_MEKK1_MAP3K1_ST	P46531	NOTCH1	Q13233	MAP3K1	T2511	H2507Y	2507	Missense	distal	-4	no	4.557	4.692	PhosphoSitePlus	COSMIC	2.285	Up-regulation
STE_STE11_MEKK1_MAP3K1_ST	P46531	NOTCH1	Q13233	MAP3K1	T2511	F2509S	2509	Missense	proximal	-2	no	4.557	4.756	PhosphoSitePlus	COSMIC	2.285	Up-regulation
STE_STE11_MEKK1_MAP3K1_ST	P46531	NOTCH1	Q13233	MAP3K1	T2511	L2510F	2510	Missense	proximal	-1	no	4.557	4.540	PhosphoSitePlus	COSMIC	2.285	Down-regulation
STE_STE11_MEKK1_MAP3K1_ST	P46531	NOTCH1	Q13233	MAP3K1	T2511	P2508A	2508	Missense	distal	-3	no	4.557	4.902	PhosphoSitePlus	COSMIC	2.285	Up-regulation
STE_STE11_MEKK1_MAP3K1_ST	P46531	NOTCH1	Q13233	MAP3K1	T2511	P2514S	2514	Missense	distal	3	no	4.557	4.551	PhosphoSitePlus	COSMIC	2.285	Down-regulation
STE_STE11_MEKK1_MAP3K1_ST	P46531	NOTCH1	Q13233	MAP3K1	T2511	S2516A	2516	Missense	distal	5	no	4.557	4.633	PhosphoSitePlus	COSMIC	2.285	Up-regulation
STE_STE11_MEKK1_MAP3K1_ST	P46531	NOTCH1	Q13233	MAP3K1	T2511	L2510R	2510	Missense	proximal	-1	no	4.557	4.531	PhosphoSitePlus	COSMIC	2.285	Down-regulation
STE_STE11_MEKK1_MAP3K1_ST	P46531	NOTCH1	Q13233	MAP3K1	T2511	S2513F	2513	Missense	proximal	2	no	4.557	3.405	PhosphoSitePlus	COSMIC	2.285	Down-regulation
STE_STE11_MEKK1_MAP3K1_ST	P46531	NOTCH1	Q13233	MAP3K1	T2511	P2514L	2514	Missense	distal	3	no	4.557	4.571	PhosphoSitePlus	COSMIC	2.285	Up-regulation
STE_STE11_MEKK1_MAP3K1_ST	P46531	NOTCH1	Q13233	MAP3K1	T2511	E2515K	2515	Missense	distal	4	no	4.557	4.639	PhosphoSitePlus	COSMIC	2.285	Up-regulation
STE_STE11_MEKK1_MAP3K1_ST	P46531	NOTCH1	Q13233	MAP3K1	T2511	L2510H	2510	Missense	proximal	-1	no	4.557	4.536	PhosphoSitePlus	COSMIC	2.285	Down-regulation
STE_STE11_MEKK1_MAP3K1_ST	P46531	NOTCH1	Q13233	MAP3K1	T2511	E2506K	2506	Missense	distal	-5	no	4.557	4.707	PhosphoSitePlus	COSMIC	2.285	Up-regulation
STE_STE11_MEKK1_MAP3K1_ST	P46531	NOTCH1	Q13233	MAP3K1	S2513	F2509S	2509	Missense	distal	-4	no	1.800	2.366	EPSD	COSMIC	2.285	Gain
STE_STE11_MEKK1_MAP3K1_ST	P46531	NOTCH1	Q13233	MAP3K1	S2516	F2509S	2509	Missense	distal	-7	no	2.280	2.309	EPSD	COSMIC	2.285	Gain
STE_STE11_MEKK1_MAP3K1_ST	P46531	NOTCH1	Q13233	MAP3K1	S2516	L2510F	2510	Missense	distal	-6	no	2.280	2.299	EPSD	COSMIC	2.285	Gain
STE_STE11_MEKK1_MAP3K1_ST	P46531	NOTCH1	Q13233	MAP3K1	S2516	L2510R	2510	Missense	distal	-6	no	2.280	2.314	EPSD	COSMIC	2.285	Gain
STE_STE11_MEKK1_MAP3K1_ST	P46531	NOTCH1	Q13233	MAP3K1	S2516	S2513F	2513	Missense	distal	-3	no	2.280	2.464	EPSD	COSMIC	2.285	Gain
STE_STE11_MEKK1_MAP3K1_ST	P46531	NOTCH1	Q13233	MAP3K1	S2516	E2515K	2515	Missense	proximal	-1	no	2.280	2.346	EPSD	COSMIC	2.285	Gain
STE_STE11_MEKK1_MAP3K1_ST	P46531	NOTCH1	Q13233	MAP3K1	S2523	P2525L	2525	Missense	proximal	2	no	2.117	2.499	EPSD	COSMIC	2.285	Gain
STE_STE11_MEKK1_MAP3K1_ST	P46531	NOTCH1	Q13233	MAP3K1	S2523	P2525S	2525	Missense	proximal	2	no	2.117	3.134	EPSD	COSMIC	2.285	Gain
STE_STE11_MEKK1_MAP3K1_ST	Q8NHW3	MAFA	Q13233	MAP3K1	S14	L11P	11	Missense	distal	-3	no	4.785	4.414	PhosphoSitePlus;EPSD	COSMIC	2.285	Down-regulation
STE_STE11_MEKK1_MAP3K1_ST	Q8NHW3	MAFA	Q13233	MAP3K1	T134	N127K	127	Missense	distal	-7	no	2.579	2.573	EPSD	COSMIC	2.285	Down-regulation
STE_STE11_MEKK1_MAP3K1_ST	Q13158	FADD	Q13233	MAP3K1	S194	S194F	194	Missense	central	0	yes	3.865	0.000	PhosphoSitePlus	COSMIC	2.285	Loss
Other_Bud32_TP53RK_ST	P04637	TP53	Q96S44	TP53RK	S15	E11Q	11	Missense	distal	-4	no	5.157	5.162	PhosphoSitePlus	COSMIC;GDSC;CCLE	2.118	Up-regulation
Other_Bud32_TP53RK_ST	P04637	TP53	Q96S44	TP53RK	S15	S20L	20	Missense	distal	5	no	5.157	5.280	PhosphoSitePlus	COSMIC	2.118	Up-regulation
Other_Bud32_TP53RK_ST	P04637	TP53	Q96S44	TP53RK	S15	Q16L	16	Missense	proximal	1	no	5.157	5.148	PhosphoSitePlus	COSMIC;GDSC;CCLE	2.118	Down-regulation
Other_Bud32_TP53RK_ST	P04637	TP53	Q96S44	TP53RK	S15	P13S	13	Missense	proximal	-2	no	5.157	5.140	PhosphoSitePlus	COSMIC	2.118	Down-regulation
Other_Bud32_TP53RK_ST	P04637	TP53	Q96S44	TP53RK	S15	E17K	17	Missense	proximal	2	no	5.157	5.131	PhosphoSitePlus	COSMIC	2.118	Down-regulation
Other_Bud32_TP53RK_ST	P04637	TP53	Q96S44	TP53RK	S15	V10I	10	Missense	distal	-5	no	5.157	4.930	PhosphoSitePlus	COSMIC	2.118	Down-regulation
Other_Bud32_TP53RK_ST	P04637	TP53	Q96S44	TP53RK	S15	P8L	8	Missense	distal	-7	no	5.157	5.168	PhosphoSitePlus	COSMIC	2.118	Up-regulation
Other_Bud32_TP53RK_ST	P04637	TP53	Q96S44	TP53RK	S15	P8S	8	Missense	distal	-7	no	5.157	5.261	PhosphoSitePlus	COSMIC	2.118	Up-regulation
Other_Bud32_TP53RK_ST	P04637	TP53	Q96S44	TP53RK	S15	P13L	13	Missense	proximal	-2	no	5.157	5.177	PhosphoSitePlus	COSMIC	2.118	Up-regulation
Other_Bud32_TP53RK_ST	P04637	TP53	Q96S44	TP53RK	S15	V10G	10	Missense	distal	-5	no	5.157	5.589	PhosphoSitePlus	COSMIC	2.118	Up-regulation
Other_Bud32_TP53RK_ST	P04637	TP53	Q96S44	TP53RK	S15	T18A	18	Missense	distal	3	no	5.157	5.133	PhosphoSitePlus	COSMIC	2.118	Down-regulation
Other_Bud32_TP53RK_ST	P04637	TP53	Q96S44	TP53RK	S15	F19S	19	Missense	distal	4	no	5.157	4.573	PhosphoSitePlus	COSMIC	2.118	Down-regulation
Other_Bud32_TP53RK_ST	P04637	TP53	Q96S44	TP53RK	S15	E17V	17	Missense	proximal	2	no	5.157	5.160	PhosphoSitePlus	COSMIC	2.118	Up-regulation
Other_Bud32_TP53RK_ST	P04637	TP53	Q96S44	TP53RK	S15	S9G	9	Missense	distal	-6	no	5.157	5.164	PhosphoSitePlus	COSMIC	2.118	Up-regulation
Other_Bud32_TP53RK_ST	P04637	TP53	Q96S44	TP53RK	S15	T18I	18	Missense	distal	3	no	5.157	5.127	PhosphoSitePlus	COSMIC	2.118	Down-regulation
Other_Bud32_TP53RK_ST	P04637	TP53	Q96S44	TP53RK	S15	T18K	18	Missense	distal	3	no	5.157	5.134	PhosphoSitePlus	COSMIC	2.118	Down-regulation
Other_Bud32_TP53RK_ST	P04637	TP53	Q96S44	TP53RK	S15	T18R	18	Missense	distal	3	no	5.157	5.137	PhosphoSitePlus	COSMIC	2.118	Down-regulation
Other_Bud32_TP53RK_ST	P04637	TP53	Q96S44	TP53RK	S15	S15I	15	Missense	central	0	yes	5.157	0.000	PhosphoSitePlus	COSMIC	2.118	Loss
Other_Bud32_TP53RK_ST	P04637	TP53	Q96S44	TP53RK	S46	M40I	40	Missense	distal	-6	no	2.106	2.119	EPSD	COSMIC	2.118	Gain
Other_Bud32_TP53RK_ST	P04637	TP53	Q96S44	TP53RK	S46	W53G	53	Missense	distal	7	no	2.106	2.541	EPSD	COSMIC	2.118	Gain
Other_Bud32_TP53RK_ST	P04637	TP53	Q96S44	TP53RK	S46	D49Y	49	Missense	distal	3	no	2.106	2.151	EPSD	COSMIC	2.118	Gain
Other_Bud32_TP53RK_ST	P04637	TP53	Q96S44	TP53RK	S46	D49H	49	Missense	distal	3	no	2.106	2.143	EPSD	COSMIC;GDSC;CCLE	2.118	Gain
Other_Bud32_TP53RK_ST	P04637	TP53	Q96S44	TP53RK	S46	D48H	48	Missense	proximal	2	no	2.106	2.136	EPSD	COSMIC	2.118	Gain
Other_Bud32_TP53RK_ST	P04637	TP53	Q96S44	TP53RK	S46	D49N	49	Missense	distal	3	no	2.106	2.188	EPSD	COSMIC	2.118	Gain
Other_Bud32_TP53RK_ST	P04637	TP53	Q96S44	TP53RK	S46	D49V	49	Missense	distal	3	no	2.106	2.174	EPSD	COSMIC	2.118	Gain
Other_Bud32_TP53RK_ST	P04637	TP53	Q96S44	TP53RK	S46	A39S	39	Missense	distal	-7	no	2.106	2.153	EPSD	COSMIC	2.118	Gain
Other_Bud32_TP53RK_ST	P04637	TP53	Q96S44	TP53RK	S46	M44V	44	Missense	proximal	-2	no	2.106	2.131	EPSD	COSMIC	2.118	Gain
Other_Bud32_TP53RK_ST	P04637	TP53	Q96S44	TP53RK	S46	L43F	43	Missense	distal	-3	no	2.106	2.210	EPSD	COSMIC	2.118	Gain
Other_Bud32_TP53RK_ST	P04637	TP53	Q96S44	TP53RK	S46	D49E	49	Missense	distal	3	no	2.106	2.285	EPSD	COSMIC	2.118	Gain
Other_Bud32_TP53RK_ST	P04637	TP53	Q96S44	TP53RK	S46	D48A	48	Missense	proximal	2	no	2.106	2.135	EPSD	COSMIC	2.118	Gain
Other_Bud32_TP53RK_ST	P04637	TP53	Q96S44	TP53RK	S46	D48E	48	Missense	proximal	2	no	2.106	2.170	EPSD	COSMIC	2.118	Gain
Other_Bud32_TP53RK_ST	P04637	TP53	Q96S44	TP53RK	S46	D49I	49	Missense	distal	3	no	2.106	2.146	EPSD	COSMIC	2.118	Gain
Other_Bud32_TP53RK_ST	P04637	TP53	Q96S44	TP53RK	S215	P219L	219	Missense	distal	4	no	1.875	2.391	EPSD	COSMIC	2.118	Gain
Other_Bud32_TP53RK_ST	P04637	TP53	Q96S44	TP53RK	S215	N210D	210	Missense	distal	-5	no	1.875	2.393	EPSD	COSMIC	2.118	Gain
Other_Bud32_TP53RK_ST	P04637	TP53	Q96S44	TP53RK	S215	P222L	222	Missense	distal	7	no	1.875	2.192	EPSD	COSMIC	2.118	Gain
Other_Bud32_TP53RK_ST	P04637	TP53	Q96S44	TP53RK	S215	P222A	222	Missense	distal	7	no	1.875	2.149	EPSD	COSMIC	2.118	Gain
TK_ALK_ALK_Y	Q9UM73	ALK	Q9UM73	ALK	Y1278	R1275X	1275	Missense	distal	-3	no	5.275	5.249	PhosphoSitePlus	COSMIC	2.462	Down-regulation
TK_ALK_ALK_Y	Q9UM73	ALK	Q9UM73	ALK	Y1278	Y1278S	1278	Missense	central	0	yes	5.275	0.000	PhosphoSitePlus	COSMIC	2.462	Loss
TK_ALK_ALK_Y	Q9UM73	ALK	Q9UM73	ALK	Y1278	G1272R	1272	Missense	distal	-6	no	5.275	4.849	PhosphoSitePlus	COSMIC	2.462	Down-regulation
TK_ALK_ALK_Y	Q9UM73	ALK	Q9UM73	ALK	Y1278	A1274T	1274	Missense	distal	-4	no	5.275	4.887	PhosphoSitePlus	COSMIC	2.462	Down-regulation
TK_ALK_ALK_Y	Q9UM73	ALK	Q9UM73	ALK	Y1278	M1273I	1273	Missense	distal	-5	no	5.275	5.288	PhosphoSitePlus	COSMIC	2.462	Up-regulation
TK_ALK_ALK_Y	Q9UM73	ALK	Q9UM73	ALK	Y1278	A1280V	1280	Missense	proximal	2	no	5.275	5.194	PhosphoSitePlus	COSMIC	2.462	Down-regulation
TK_ALK_ALK_Y	Q9UM73	ALK	Q9UM73	ALK	Y1278	K1285N	1285	Missense	distal	7	no	5.275	4.926	PhosphoSitePlus	COSMIC	2.462	Down-regulation
TK_ALK_ALK_Y	Q9UM73	ALK	Q9UM73	ALK	Y1278	I1277T	1277	Missense	proximal	-1	no	5.275	5.289	PhosphoSitePlus	COSMIC	2.462	Up-regulation
TK_ALK_ALK_Y	Q9UM73	ALK	Q9UM73	ALK	Y1282	R1275X	1275	Missense	distal	-7	no	5.394	5.295	EPSD	COSMIC	2.462	Down-regulation
TK_ALK_ALK_Y	Q9UM73	ALK	Q9UM73	ALK	Y1282	Y1278S	1278	Missense	distal	-4	no	5.394	5.627	EPSD	COSMIC	2.462	Up-regulation
TK_ALK_ALK_Y	Q9UM73	ALK	Q9UM73	ALK	Y1282	A1280V	1280	Missense	proximal	-2	no	5.394	5.216	EPSD	COSMIC	2.462	Down-regulation
TK_ALK_ALK_Y	Q9UM73	ALK	Q9UM73	ALK	Y1282	G1286R	1286	Missense	distal	4	no	5.394	5.239	EPSD	COSMIC	2.462	Down-regulation
TK_ALK_ALK_Y	Q9UM73	ALK	Q9UM73	ALK	Y1282	K1285N	1285	Missense	distal	3	no	5.394	5.400	EPSD	COSMIC	2.462	Up-regulation
TK_ALK_ALK_Y	Q9UM73	ALK	Q9UM73	ALK	Y1282	I1277T	1277	Missense	distal	-5	no	5.394	5.397	EPSD	COSMIC	2.462	Up-regulation
TK_ALK_ALK_Y	Q9UM73	ALK	Q9UM73	ALK	Y1283	Y1278S	1278	Missense	distal	-5	no	5.097	4.920	EPSD	COSMIC	2.462	Down-regulation
TK_ALK_ALK_Y	Q9UM73	ALK	Q9UM73	ALK	Y1283	A1280V	1280	Missense	distal	-3	no	5.097	5.088	EPSD	COSMIC	2.462	Down-regulation
TK_ALK_ALK_Y	Q9UM73	ALK	Q9UM73	ALK	Y1283	G1286R	1286	Missense	distal	3	no	5.097	5.084	EPSD	COSMIC	2.462	Down-regulation
TK_ALK_ALK_Y	Q9UM73	ALK	Q9UM73	ALK	Y1283	K1285N	1285	Missense	proximal	2	no	5.097	5.038	EPSD	COSMIC	2.462	Down-regulation
TK_ALK_ALK_Y	Q9UM73	ALK	Q9UM73	ALK	Y1283	I1277T	1277	Missense	distal	-6	no	5.097	4.842	EPSD	COSMIC	2.462	Down-regulation
TK_ALK_ALK_Y	P23246	SFPQ	Q9UM73	ALK	Y293	R287S	287	Missense	distal	-6	no	5.156	5.031	PhosphoSitePlus	COSMIC	2.462	Down-regulation
TK_ALK_ALK_Y	P40763	STAT3	Q9UM73	ALK	Y705	D698N	698	Missense	distal	-7	no	5.411	5.351	PhosphoSitePlus	COSMIC	2.462	Down-regulation
TK_ALK_ALK_Y	P40763	STAT3	Q9UM73	ALK	Y705	G700R	700	Missense	distal	-5	no	5.411	5.128	PhosphoSitePlus	COSMIC	2.462	Down-regulation
TK_ALK_ALK_Y	P40763	STAT3	Q9UM73	ALK	Y705	I711L	711	Missense	distal	6	no	5.411	5.397	PhosphoSitePlus	COSMIC	2.462	Down-regulation
TK_ALK_ALK_Y	Q06124	PTPN11	Q9UM73	ALK	Y546	S552F	552	Missense	distal	6	no	5.403	5.430	EPSD	COSMIC	2.462	Up-regulation
TK_ALK_ALK_Y	Q06124	PTPN11	Q9UM73	ALK	Y546	E545K	545	Missense	proximal	-1	no	5.403	5.291	EPSD	COSMIC	2.462	Down-regulation
TK_ALK_ALK_Y	Q06124	PTPN11	Q9UM73	ALK	Y546	E545D	545	Missense	proximal	-1	no	5.403	5.259	EPSD	COSMIC	2.462	Down-regulation
TK_ALK_ALK_Y	Q06124	PTPN11	Q9UM73	ALK	Y546	I549L	549	Missense	distal	3	no	5.403	5.417	EPSD	COSMIC	2.462	Up-regulation
TK_ALK_ALK_Y	Q06124	PTPN11	Q9UM73	ALK	Y546	Y546C	546	Missense	central	0	yes	5.403	0.000	EPSD	COSMIC	2.462	Loss
TK_ALK_ALK_Y	Q06124	PTPN11	Q9UM73	ALK	Y546	N548T	548	Missense	proximal	2	no	5.403	5.334	EPSD	COSMIC	2.462	Down-regulation
TK_ALK_ALK_Y	Q06124	PTPN11	Q9UM73	ALK	Y546	G543E	543	Missense	distal	-3	no	5.403	5.415	EPSD	COSMIC	2.462	Up-regulation
TK_ALK_ALK_Y	Q06124	PTPN11	Q9UM73	ALK	Y584	D579E	579	Missense	distal	-5	no	4.823	4.461	EPSD	COSMIC	2.462	Down-regulation
TK_ALK_ALK_Y	Q06124	PTPN11	Q9UM73	ALK	Y584	R582G	582	Missense	proximal	-2	no	4.823	4.578	EPSD	COSMIC	2.462	Down-regulation
TK_ALK_ALK_Y	Q06124	PTPN11	Q9UM73	ALK	Y584	V583A	583	Missense	proximal	-1	no	4.823	4.794	EPSD	COSMIC	2.462	Down-regulation
TK_ALK_ALK_Y	Q06124	PTPN11	Q9UM73	ALK	Y584	V587A	587	Missense	distal	3	no	4.823	4.811	EPSD	COSMIC	2.462	Down-regulation
TK_ALK_ALK_Y	Q06124	PTPN11	Q9UM73	ALK	Y584	S580I	580	Missense	distal	-4	no	4.823	4.559	EPSD	COSMIC	2.462	Down-regulation
TK_ALK_ALK_Y	P62993	GRB2	Q9UM73	ALK	Y160	D166V	166	Missense	distal	6	no	5.249	5.251	PhosphoSitePlus	COSMIC	2.462	Up-regulation
TK_ALK_ALK_Y	P62993	GRB2	Q9UM73	ALK	Y160	L164I	164	Missense	distal	4	no	5.249	5.042	PhosphoSitePlus	COSMIC	2.462	Down-regulation
AGC_RSK_MSK_RPS6KA5_ST	P16220	CREB1	O75582	RPS6KA5	S98	S103N	103	Missense	distal	5	no	1.750	1.742	EPSD	COSMIC	1.456	Down-regulation
AGC_RSK_MSK_RPS6KA5_ST	P16220	CREB1	O75582	RPS6KA5	S98	R95I	95	Missense	distal	-3	no	1.750	0.698	EPSD	COSMIC	1.456	Loss
AGC_RSK_MSK_RPS6KA5_ST	P16220	CREB1	O75582	RPS6KA5	S98	I102M	102	Missense	distal	4	no	1.750	1.759	EPSD	COSMIC	1.456	Up-regulation
AGC_RSK_MSK_RPS6KA5_ST	P16220	CREB1	O75582	RPS6KA5	S108	S103N	103	Missense	distal	-5	no	1.753	1.747	EPSD	COSMIC	1.456	Down-regulation
AGC_RSK_MSK_RPS6KA5_ST	P16220	CREB1	O75582	RPS6KA5	S108	E109K	109	Missense	proximal	1	no	1.753	1.742	EPSD	COSMIC	1.456	Down-regulation
AGC_RSK_MSK_RPS6KA5_ST	P16220	CREB1	O75582	RPS6KA5	S108	I102M	102	Missense	distal	-6	no	1.753	1.749	EPSD	COSMIC	1.456	Down-regulation
AGC_RSK_MSK_RPS6KA5_ST	P16220	CREB1	O75582	RPS6KA5	S111	E109K	109	Missense	proximal	-2	no	1.214	1.725	EPSD	COSMIC	1.456	Gain
AGC_RSK_MSK_RPS6KA5_ST	P16220	CREB1	O75582	RPS6KA5	S114	S117N	117	Missense	distal	3	no	1.594	1.603	EPSD	COSMIC	1.456	Up-regulation
AGC_RSK_MSK_RPS6KA5_ST	P16220	CREB1	O75582	RPS6KA5	S114	V118L	118	Missense	distal	4	no	1.594	1.612	EPSD	COSMIC	1.456	Up-regulation
AGC_RSK_MSK_RPS6KA5_ST	P16220	CREB1	O75582	RPS6KA5	S114	E109K	109	Missense	distal	-5	no	1.594	1.608	EPSD	COSMIC	1.456	Up-regulation
AGC_RSK_MSK_RPS6KA5_ST	P16220	CREB1	O75582	RPS6KA5	S114	V118I	118	Missense	distal	4	no	1.594	1.608	EPSD	COSMIC	1.456	Up-regulation
AGC_RSK_MSK_RPS6KA5_ST	P16220	CREB1	O75582	RPS6KA5	S133	L128R	128	Missense	distal	-5	no	3.674	3.715	PhosphoSitePlus	COSMIC	1.456	Up-regulation
AGC_RSK_MSK_RPS6KA5_ST	P16220	CREB1	O75582	RPS6KA5	S270	A269T	269	Missense	proximal	-1	no	1.461	1.431	EPSD	COSMIC	1.456	Loss
AGC_RSK_MSK_RPS6KA5_ST	P16220	CREB1	O75582	RPS6KA5	S270	P264T	264	Missense	distal	-6	no	1.461	1.465	EPSD	COSMIC;GDSC;CCLE	1.456	Up-regulation
AGC_RSK_MSK_RPS6KA5_ST	P16220	CREB1	O75582	RPS6KA5	S271	A269T	269	Missense	proximal	-2	no	1.550	0.831	EPSD	COSMIC	1.456	Loss
AGC_RSK_MSK_RPS6KA5_ST	P16220	CREB1	O75582	RPS6KA5	S271	P264T	264	Missense	distal	-7	no	1.550	1.559	EPSD	COSMIC;GDSC;CCLE	1.456	Up-regulation
AGC_RSK_MSK_RPS6KA5_ST	O75582	RPS6KA5	O75582	RPS6KA5	S212	F213V	213	Missense	proximal	1	no	2.933	2.936	EPSD;PhosphoSitePlus	COSMIC	1.456	Up-regulation
AGC_RSK_MSK_RPS6KA5_ST	O75582	RPS6KA5	O75582	RPS6KA5	S212	Y219C	219	Missense	distal	7	no	2.933	2.930	EPSD;PhosphoSitePlus	COSMIC	1.456	Down-regulation
AGC_RSK_MSK_RPS6KA5_ST	O75582	RPS6KA5	O75582	RPS6KA5	S212	E206K	206	Missense	distal	-6	no	2.933	2.904	EPSD;PhosphoSitePlus	COSMIC	1.456	Down-regulation
AGC_RSK_MSK_RPS6KA5_ST	O75582	RPS6KA5	O75582	RPS6KA5	S253	G251R	251	Missense	proximal	-2	no	1.025	2.755	EPSD	COSMIC	1.456	Gain
AGC_RSK_MSK_RPS6KA5_ST	O75582	RPS6KA5	O75582	RPS6KA5	S381	R386H	386	Missense	distal	5	no	1.719	1.704	EPSD;PhosphoSitePlus	COSMIC	1.456	Down-regulation
AGC_RSK_MSK_RPS6KA5_ST	O75582	RPS6KA5	O75582	RPS6KA5	S694	Q692R	692	Missense	proximal	-2	no	1.132	2.719	EPSD	COSMIC	1.456	Gain
AGC_RSK_MSK_RPS6KA5_ST	O75582	RPS6KA5	O75582	RPS6KA5	S695	Q692R	692	Missense	distal	-3	no	0.890	1.816	EPSD	COSMIC	1.456	Gain
AGC_RSK_MSK_RPS6KA5_ST	O75582	RPS6KA5	O75582	RPS6KA5	S750	T755M	755	Missense	distal	5	no	1.561	1.570	EPSD;PhosphoSitePlus	COSMIC;GDSC;CCLE	1.456	Up-regulation
AGC_RSK_MSK_RPS6KA5_ST	O75582	RPS6KA5	O75582	RPS6KA5	S750	R756C	756	Missense	distal	6	no	1.561	1.567	EPSD;PhosphoSitePlus	COSMIC	1.456	Up-regulation
AGC_RSK_MSK_RPS6KA5_ST	O75582	RPS6KA5	O75582	RPS6KA5	S750	E754D	754	Missense	distal	4	no	1.561	1.557	EPSD;PhosphoSitePlus	COSMIC	1.456	Down-regulation
AGC_RSK_MSK_RPS6KA5_ST	O75582	RPS6KA5	O75582	RPS6KA5	S750	E754K	754	Missense	distal	4	no	1.561	1.591	EPSD;PhosphoSitePlus	COSMIC	1.456	Up-regulation
AGC_RSK_MSK_RPS6KA5_ST	O75582	RPS6KA5	O75582	RPS6KA5	S758	E761K	761	Missense	distal	3	no	2.440	2.464	EPSD;PhosphoSitePlus	COSMIC	1.456	Up-regulation
AGC_RSK_MSK_RPS6KA5_ST	O75582	RPS6KA5	O75582	RPS6KA5	S758	T755M	755	Missense	distal	-3	no	2.440	2.491	EPSD;PhosphoSitePlus	COSMIC;GDSC;CCLE	1.456	Up-regulation
AGC_RSK_MSK_RPS6KA5_ST	O75582	RPS6KA5	O75582	RPS6KA5	S758	R756C	756	Missense	proximal	-2	no	2.440	0.759	EPSD;PhosphoSitePlus	COSMIC	1.456	Loss
AGC_RSK_MSK_RPS6KA5_ST	O75582	RPS6KA5	O75582	RPS6KA5	S758	E754D	754	Missense	distal	-4	no	2.440	2.449	EPSD;PhosphoSitePlus	COSMIC	1.456	Up-regulation
AGC_RSK_MSK_RPS6KA5_ST	O75582	RPS6KA5	O75582	RPS6KA5	S758	E754K	754	Missense	distal	-4	no	2.440	2.386	EPSD;PhosphoSitePlus	COSMIC	1.456	Down-regulation
AGC_RSK_MSK_RPS6KA5_ST	O75582	RPS6KA5	O75582	RPS6KA5	S759	E761K	761	Missense	proximal	2	no	2.201	2.227	EPSD	COSMIC	1.456	Up-regulation
AGC_RSK_MSK_RPS6KA5_ST	O75582	RPS6KA5	O75582	RPS6KA5	S759	T755M	755	Missense	distal	-4	no	2.201	2.138	EPSD	COSMIC;GDSC;CCLE	1.456	Down-regulation
AGC_RSK_MSK_RPS6KA5_ST	O75582	RPS6KA5	O75582	RPS6KA5	S759	R756C	756	Missense	distal	-3	no	2.201	1.226	EPSD	COSMIC	1.456	Loss
AGC_RSK_MSK_RPS6KA5_ST	O75582	RPS6KA5	O75582	RPS6KA5	S759	S766P	766	Missense	distal	7	no	2.201	2.239	EPSD	COSMIC	1.456	Up-regulation
AGC_RSK_MSK_RPS6KA5_ST	O75582	RPS6KA5	O75582	RPS6KA5	S759	E754K	754	Missense	distal	-5	no	2.201	2.215	EPSD	COSMIC	1.456	Up-regulation
AGC_RSK_MSK_RPS6KA5_ST	P10276	RARA	O75582	RPS6KA5	S219	E215G	215	Missense	distal	-4	no	2.659	2.657	EPSD	COSMIC	1.456	Down-regulation
AGC_RSK_MSK_RPS6KA5_ST	P10276	RARA	O75582	RPS6KA5	S219	S219Y	219	Missense	central	0	yes	2.659	0.000	EPSD	COSMIC	1.456	Loss
AGC_RSK_MSK_RPS6KA5_ST	P10276	RARA	O75582	RPS6KA5	S219	D221G	221	Missense	proximal	2	no	2.659	2.663	EPSD	COSMIC	1.456	Up-regulation
AGC_RSK_MSK_RPS6KA5_ST	P10276	RARA	O75582	RPS6KA5	S219	L220V	220	Missense	proximal	1	no	2.659	2.662	EPSD	COSMIC	1.456	Up-regulation
AGC_RSK_MSK_RPS6KA5_ST	P10276	RARA	O75582	RPS6KA5	S219	S214Y	214	Missense	distal	-5	no	2.659	2.654	EPSD	COSMIC	1.456	Down-regulation
AGC_RSK_MSK_RPS6KA5_ST	P10276	RARA	O75582	RPS6KA5	S369	H372Y	372	Missense	distal	3	no	3.638	3.623	PhosphoSitePlus	COSMIC	1.456	Down-regulation
AGC_RSK_MSK_RPS6KA5_ST	P10276	RARA	O75582	RPS6KA5	S369	R370H	370	Missense	proximal	1	no	3.638	3.653	PhosphoSitePlus	COSMIC;GDSC	1.456	Up-regulation
AGC_RSK_MSK_RPS6KA5_ST	P10276	RARA	O75582	RPS6KA5	S369	V363M	363	Missense	distal	-6	no	3.638	3.623	PhosphoSitePlus	COSMIC;GDSC;CCLE	1.456	Down-regulation
AGC_RSK_MSK_RPS6KA5_ST	P10276	RARA	O75582	RPS6KA5	S369	P371R	371	Missense	proximal	2	no	3.638	3.712	PhosphoSitePlus	COSMIC	1.456	Up-regulation
AGC_RSK_MSK_RPS6KA5_ST	P10276	RARA	O75582	RPS6KA5	S369	R367K	367	Missense	proximal	-2	no	3.638	2.284	PhosphoSitePlus	COSMIC	1.456	Down-regulation
AGC_RSK_MSK_RPS6KA5_ST	P10276	RARA	O75582	RPS6KA5	S456	P450F	450	Missense	distal	-6	no	2.660	2.658	EPSD	COSMIC	1.456	Down-regulation
AGC_RSK_MSK_RPS6KA5_ST	P10276	RARA	O75582	RPS6KA5	S456	S461C	461	Missense	distal	5	no	2.660	2.653	EPSD	COSMIC	1.456	Down-regulation
AGC_RSK_MSK_RPS6KA5_ST	P10276	RARA	O75582	RPS6KA5	S456	R454K	454	Missense	proximal	-2	no	2.660	1.306	EPSD	COSMIC	1.456	Loss
AGC_RSK_MSK_RPS6KA5_ST	P10276	RARA	O75582	RPS6KA5	S456	P457L	457	Missense	proximal	1	no	2.660	2.657	EPSD	COSMIC	1.456	Down-regulation
AGC_RSK_MSK_RPS6KA5_ST	P10276	RARA	O75582	RPS6KA5	S456	S452F	452	Missense	distal	-4	no	2.660	2.696	EPSD	COSMIC	1.456	Up-regulation
AGC_RSK_MSK_RPS6KA5_ST	P10276	RARA	O75582	RPS6KA5	S456	A458S	458	Missense	proximal	2	no	2.660	2.654	EPSD	COSMIC;CCLE	1.456	Down-regulation
AGC_RSK_MSK_RPS6KA5_ST	P10276	RARA	O75582	RPS6KA5	S456	S456R	456	Missense	central	0	yes	2.660	0.000	EPSD	COSMIC;CCLE	1.456	Loss
AGC_RSK_MSK_RPS6KA5_ST	P10276	RARA	O75582	RPS6KA5	S456	S451R	451	Missense	distal	-5	no	2.660	2.695	EPSD	COSMIC	1.456	Up-regulation
AGC_RSK_MSK_RPS6KA5_ST	P10276	RARA	O75582	RPS6KA5	S456	P457S	457	Missense	proximal	1	no	2.660	2.664	EPSD	COSMIC	1.456	Up-regulation
AGC_RSK_MSK_RPS6KA5_ST	P10276	RARA	O75582	RPS6KA5	S456	S456C	456	Missense	central	0	yes	2.660	0.000	EPSD	COSMIC	1.456	Loss
AGC_RSK_MSK_RPS6KA5_ST	P54253	ATXN1	O75582	RPS6KA5	S25	R24P	24	Missense	proximal	-1	no	1.538	1.502	EPSD	COSMIC	1.456	Down-regulation
AGC_RSK_MSK_RPS6KA5_ST	P54253	ATXN1	O75582	RPS6KA5	S25	S26F	26	Missense	proximal	1	no	1.538	1.531	EPSD	COSMIC	1.456	Down-regulation
AGC_RSK_MSK_RPS6KA5_ST	P54253	ATXN1	O75582	RPS6KA5	S26	R24P	24	Missense	proximal	-2	no	2.709	0.842	EPSD	COSMIC	1.456	Loss
AGC_RSK_MSK_RPS6KA5_ST	P54253	ATXN1	O75582	RPS6KA5	S26	A30S	30	Missense	distal	4	no	2.709	2.689	EPSD	COSMIC	1.456	Down-regulation
AGC_RSK_MSK_RPS6KA5_ST	P54253	ATXN1	O75582	RPS6KA5	S26	S26F	26	Missense	central	0	yes	2.709	0.000	EPSD	COSMIC	1.456	Loss
AGC_RSK_MSK_RPS6KA5_ST	P54253	ATXN1	O75582	RPS6KA5	S82	A80T	80	Missense	proximal	-2	no	1.492	0.773	EPSD	COSMIC	1.456	Loss
AGC_RSK_MSK_RPS6KA5_ST	P54253	ATXN1	O75582	RPS6KA5	S82	P89T	89	Missense	distal	7	no	1.492	1.505	EPSD	COSMIC	1.456	Up-regulation
AGC_RSK_MSK_RPS6KA5_ST	P54253	ATXN1	O75582	RPS6KA5	S82	P89S	89	Missense	distal	7	no	1.492	1.455	EPSD	COSMIC	1.456	Loss
AGC_RSK_MSK_RPS6KA5_ST	P54253	ATXN1	O75582	RPS6KA5	S91	P89S	89	Missense	proximal	-2	no	1.066	1.529	EPSD	COSMIC	1.456	Gain
AGC_RSK_MSK_RPS6KA5_ST	P54253	ATXN1	O75582	RPS6KA5	S262	G258C	258	Missense	distal	-4	no	1.676	1.669	EPSD	COSMIC	1.456	Down-regulation
AGC_RSK_MSK_RPS6KA5_ST	P54253	ATXN1	O75582	RPS6KA5	S406	E404D	404	Missense	proximal	-2	no	2.009	2.048	EPSD	COSMIC	1.456	Up-regulation
AGC_RSK_MSK_RPS6KA5_ST	P54253	ATXN1	O75582	RPS6KA5	S406	R403H	403	Missense	distal	-3	no	2.009	1.095	EPSD	COSMIC	1.456	Loss
AGC_RSK_MSK_RPS6KA5_ST	P54253	ATXN1	O75582	RPS6KA5	S406	A405T	405	Missense	proximal	-1	no	2.009	1.979	EPSD	COSMIC	1.456	Down-regulation
AGC_RSK_MSK_RPS6KA5_ST	P54253	ATXN1	O75582	RPS6KA5	S406	L410V	410	Missense	distal	4	no	2.009	1.992	EPSD	COSMIC	1.456	Down-regulation
AGC_RSK_MSK_RPS6KA5_ST	P54253	ATXN1	O75582	RPS6KA5	S408	E404D	404	Missense	distal	-4	no	1.720	1.729	EPSD	COSMIC	1.456	Up-regulation
AGC_RSK_MSK_RPS6KA5_ST	P54253	ATXN1	O75582	RPS6KA5	S408	R403H	403	Missense	distal	-5	no	1.720	1.684	EPSD	COSMIC	1.456	Down-regulation
AGC_RSK_MSK_RPS6KA5_ST	P54253	ATXN1	O75582	RPS6KA5	S408	D412N	412	Missense	distal	4	no	1.720	1.724	EPSD	COSMIC	1.456	Up-regulation
AGC_RSK_MSK_RPS6KA5_ST	P54253	ATXN1	O75582	RPS6KA5	S408	G415D	415	Missense	distal	7	no	1.720	1.724	EPSD	COSMIC	1.456	Up-regulation
AGC_RSK_MSK_RPS6KA5_ST	P54253	ATXN1	O75582	RPS6KA5	S408	A405T	405	Missense	distal	-3	no	1.720	1.330	EPSD	COSMIC	1.456	Loss
AGC_RSK_MSK_RPS6KA5_ST	P54253	ATXN1	O75582	RPS6KA5	S408	L410V	410	Missense	proximal	2	no	1.720	1.711	EPSD	COSMIC	1.456	Down-regulation
AGC_RSK_MSK_RPS6KA5_ST	P18846	ATF1	O75582	RPS6KA5	S36	E39G	39	Missense	distal	3	no	1.454	1.464	EPSD	COSMIC	1.456	Gain
AGC_RSK_MSK_RPS6KA5_ST	P18846	ATF1	O75582	RPS6KA5	S36	E39K	39	Missense	distal	3	no	1.454	1.479	EPSD	COSMIC	1.456	Gain
AGC_RSK_MSK_RPS6KA5_ST	P18846	ATF1	O75582	RPS6KA5	S41	E39K	39	Missense	proximal	-2	no	1.048	1.559	EPSD	COSMIC	1.456	Gain
AGC_RSK_MSK_RPS6KA5_ST	P18846	ATF1	O75582	RPS6KA5	S63	P62L	62	Missense	proximal	-1	no	4.068	4.071	PhosphoSitePlus	COSMIC;CCLE	1.456	Up-regulation
AGC_RSK_MSK_RPS6KA5_ST	P18846	ATF1	O75582	RPS6KA5	S189	P191A	191	Missense	proximal	2	no	1.428	1.462	EPSD	COSMIC	1.456	Gain
AGC_RSK_MSK_RPS6KA5_ST	P18846	ATF1	O75582	RPS6KA5	S189	R182G	182	Missense	distal	-7	no	1.428	1.500	EPSD	COSMIC;GDSC;CCLE	1.456	Gain
AGC_RSK_MSK_RPS6KA5_ST	Q04206	RELA	O75582	RPS6KA5	S45	E39Q	39	Missense	distal	-6	no	1.469	1.453	EPSD	COSMIC	1.456	Loss
AGC_RSK_MSK_RPS6KA5_ST	Q04206	RELA	O75582	RPS6KA5	S131	R124W	124	Missense	distal	-7	no	1.423	1.494	EPSD	COSMIC	1.456	Gain
AGC_RSK_MSK_RPS6KA5_ST	Q04206	RELA	O75582	RPS6KA5	S238	S240L	240	Missense	proximal	2	no	3.013	2.988	EPSD	COSMIC	1.456	Down-regulation
AGC_RSK_MSK_RPS6KA5_ST	Q04206	RELA	O75582	RPS6KA5	S269	R267C	267	Missense	proximal	-2	no	2.579	0.898	EPSD	COSMIC	1.456	Loss
AGC_RSK_MSK_RPS6KA5_ST	Q04206	RELA	O75582	RPS6KA5	S269	R274Q	274	Missense	distal	5	no	2.579	2.562	EPSD	COSMIC	1.456	Down-regulation
AGC_RSK_MSK_RPS6KA5_ST	Q04206	RELA	O75582	RPS6KA5	S276	R274Q	274	Missense	proximal	-2	no	4.060	2.473	PhosphoSitePlus	COSMIC	1.456	Down-regulation
AGC_RSK_MSK_RPS6KA5_ST	Q04206	RELA	O75582	RPS6KA5	S276	R278Q	278	Missense	proximal	2	no	4.060	4.002	PhosphoSitePlus	COSMIC	1.456	Down-regulation
AGC_RSK_MSK_RPS6KA5_ST	Q04206	RELA	O75582	RPS6KA5	S281	D277N	277	Missense	distal	-4	no	2.260	2.247	EPSD	COSMIC;CCLE	1.456	Down-regulation
AGC_RSK_MSK_RPS6KA5_ST	Q04206	RELA	O75582	RPS6KA5	S281	R274Q	274	Missense	distal	-7	no	2.260	2.325	EPSD	COSMIC	1.456	Up-regulation
AGC_RSK_MSK_RPS6KA5_ST	Q04206	RELA	O75582	RPS6KA5	S281	R278Q	278	Missense	distal	-3	no	2.260	1.334	EPSD	COSMIC	1.456	Loss
AGC_RSK_MSK_RPS6KA5_ST	Q04206	RELA	O75582	RPS6KA5	S316	M313I	313	Missense	distal	-3	no	1.662	1.624	EPSD	COSMIC	1.456	Down-regulation
AGC_RSK_MSK_RPS6KA5_ST	Q04206	RELA	O75582	RPS6KA5	S316	K314N	314	Missense	proximal	-2	no	1.662	1.220	EPSD	COSMIC	1.456	Loss
AGC_RSK_MSK_RPS6KA5_ST	Q04206	RELA	O75582	RPS6KA5	S338	P334S	334	Missense	distal	-4	no	2.724	2.684	EPSD	COSMIC	1.456	Down-regulation
AGC_RSK_MSK_RPS6KA5_ST	Q9H4A3	WNK1	O75582	RPS6KA5	T60	R58Q	58	Missense	proximal	-2	no	2.066	0.479	PhosphoSitePlus	COSMIC	1.456	Loss
AGC_RSK_MSK_RPS6KA5_ST	Q9H4A3	WNK1	O75582	RPS6KA5	S167	S167F	167	Missense	central	0	yes	1.931	0.000	EPSD	COSMIC	1.456	Loss
AGC_RSK_MSK_RPS6KA5_ST	Q9H4A3	WNK1	O75582	RPS6KA5	S167	V166L	166	Missense	proximal	-1	no	1.931	1.943	EPSD	COSMIC	1.456	Up-regulation
AGC_RSK_MSK_RPS6KA5_ST	Q9H4A3	WNK1	O75582	RPS6KA5	S231	G228D	228	Missense	distal	-3	no	2.509	2.445	EPSD	COSMIC	1.456	Down-regulation
AGC_RSK_MSK_RPS6KA5_ST	Q9H4A3	WNK1	O75582	RPS6KA5	S306	L303R	303	Missense	distal	-3	no	1.293	2.339	EPSD	COSMIC	1.456	Gain
AGC_RSK_MSK_RPS6KA5_ST	Q9H4A3	WNK1	O75582	RPS6KA5	S378	L374R	374	Missense	distal	-4	no	2.926	2.808	EPSD	COSMIC	1.456	Down-regulation
AGC_RSK_MSK_RPS6KA5_ST	Q9H4A3	WNK1	O75582	RPS6KA5	S378	A372P	372	Missense	distal	-6	no	2.926	2.965	EPSD	COSMIC	1.456	Up-regulation
AGC_RSK_MSK_RPS6KA5_ST	Q9H4A3	WNK1	O75582	RPS6KA5	S378	S378P	378	Missense	central	0	yes	2.926	0.000	EPSD	COSMIC	1.456	Loss
AGC_RSK_MSK_RPS6KA5_ST	Q9H4A3	WNK1	O75582	RPS6KA5	T436	S437R	437	Missense	proximal	1	no	1.714	1.687	EPSD	COSMIC	1.456	Down-regulation
AGC_RSK_MSK_RPS6KA5_ST	Q9H4A3	WNK1	O75582	RPS6KA5	T436	S443T	443	Missense	distal	7	no	1.714	1.764	EPSD	COSMIC	1.456	Up-regulation
AGC_RSK_MSK_RPS6KA5_ST	Q9H4A3	WNK1	O75582	RPS6KA5	T436	V439A	439	Missense	distal	3	no	1.714	1.761	EPSD	COSMIC	1.456	Up-regulation
AGC_RSK_MSK_RPS6KA5_ST	Q9H4A3	WNK1	O75582	RPS6KA5	T436	A429V	429	Missense	distal	-7	no	1.714	1.753	EPSD	COSMIC	1.456	Up-regulation
AGC_RSK_MSK_RPS6KA5_ST	Q9H4A3	WNK1	O75582	RPS6KA5	S437	S437R	437	Missense	central	0	yes	1.497	0.000	EPSD	COSMIC	1.456	Loss
AGC_RSK_MSK_RPS6KA5_ST	Q9H4A3	WNK1	O75582	RPS6KA5	S437	S443T	443	Missense	distal	6	no	1.497	1.508	EPSD	COSMIC	1.456	Up-regulation
AGC_RSK_MSK_RPS6KA5_ST	Q9H4A3	WNK1	O75582	RPS6KA5	S437	V439A	439	Missense	proximal	2	no	1.497	1.537	EPSD	COSMIC	1.456	Up-regulation
AGC_RSK_MSK_RPS6KA5_ST	Q9H4A3	WNK1	O75582	RPS6KA5	S469	Q462K	462	Missense	distal	-7	no	2.679	2.665	EPSD	COSMIC	1.456	Down-regulation
AGC_RSK_MSK_RPS6KA5_ST	Q9H4A3	WNK1	O75582	RPS6KA5	S469	I470V	470	Missense	proximal	1	no	2.679	2.681	EPSD	COSMIC	1.456	Up-regulation
AGC_RSK_MSK_RPS6KA5_ST	Q9H4A3	WNK1	O75582	RPS6KA5	S563	R561S	561	Missense	proximal	-2	no	2.710	1.307	EPSD	COSMIC	1.456	Loss
AGC_RSK_MSK_RPS6KA5_ST	Q9H4A3	WNK1	O75582	RPS6KA5	S563	R561I	561	Missense	proximal	-2	no	2.710	0.900	EPSD	COSMIC;GDSC;CCLE	1.456	Loss
AGC_RSK_MSK_RPS6KA5_ST	Q9H4A3	WNK1	O75582	RPS6KA5	S1105	R1100Q	1100	Missense	distal	-5	no	2.890	2.854	EPSD	COSMIC	1.456	Down-regulation
AGC_RSK_MSK_RPS6KA5_ST	Q9H4A3	WNK1	O75582	RPS6KA5	S1105	S1110C	1110	Missense	distal	5	no	2.890	2.883	EPSD	COSMIC	1.456	Down-regulation
AGC_RSK_MSK_RPS6KA5_ST	Q9H4A3	WNK1	O75582	RPS6KA5	S1105	H1112Y	1112	Missense	distal	7	no	2.890	2.900	EPSD	COSMIC;GDSC;CCLE	1.456	Up-regulation
AGC_RSK_MSK_RPS6KA5_ST	Q9H4A3	WNK1	O75582	RPS6KA5	S1105	R1107K	1107	Missense	proximal	2	no	2.890	2.842	EPSD	COSMIC	1.456	Down-regulation
AGC_RSK_MSK_RPS6KA5_ST	Q9H4A3	WNK1	O75582	RPS6KA5	S1105	T1098I	1098	Missense	distal	-7	no	2.890	2.873	EPSD	COSMIC	1.456	Down-regulation
AGC_RSK_MSK_RPS6KA5_ST	Q9H4A3	WNK1	O75582	RPS6KA5	S1110	S1110C	1110	Missense	central	0	yes	2.208	0.000	EPSD	COSMIC	1.456	Loss
AGC_RSK_MSK_RPS6KA5_ST	Q9H4A3	WNK1	O75582	RPS6KA5	S1110	H1112Y	1112	Missense	proximal	2	no	2.208	2.199	EPSD	COSMIC;GDSC;CCLE	1.456	Down-regulation
AGC_RSK_MSK_RPS6KA5_ST	Q9H4A3	WNK1	O75582	RPS6KA5	S1110	R1107K	1107	Missense	distal	-3	no	2.208	1.457	EPSD	COSMIC	1.456	Down-regulation
AGC_RSK_MSK_RPS6KA5_ST	Q9H4A3	WNK1	O75582	RPS6KA5	S1218	G1216R	1216	Missense	proximal	-2	no	0.990	2.721	EPSD	COSMIC	1.456	Gain
AGC_RSK_MSK_RPS6KA5_ST	Q9H4A3	WNK1	O75582	RPS6KA5	S1235	A1233T	1233	Missense	proximal	-2	no	1.550	0.831	EPSD	COSMIC	1.456	Loss
AGC_RSK_MSK_RPS6KA5_ST	Q9H4A3	WNK1	O75582	RPS6KA5	S1235	P1230S	1230	Missense	distal	-5	no	1.550	1.558	EPSD	COSMIC	1.456	Up-regulation
AGC_RSK_MSK_RPS6KA5_ST	Q9H4A3	WNK1	O75582	RPS6KA5	S1235	A1233V	1233	Missense	proximal	-2	no	1.550	0.812	EPSD	COSMIC	1.456	Loss
AGC_RSK_MSK_RPS6KA5_ST	Q9H4A3	WNK1	O75582	RPS6KA5	S1285	A1287S	1287	Missense	proximal	2	no	1.504	1.498	EPSD	COSMIC	1.456	Down-regulation
AGC_RSK_MSK_RPS6KA5_ST	Q9H4A3	WNK1	O75582	RPS6KA5	S1285	A1284E	1284	Missense	proximal	-1	no	1.504	1.480	EPSD	COSMIC	1.456	Down-regulation
AGC_RSK_MSK_RPS6KA5_ST	Q9H4A3	WNK1	O75582	RPS6KA5	S1285	A1283D	1283	Missense	proximal	-2	no	1.504	0.844	EPSD	COSMIC	1.456	Loss
AGC_RSK_MSK_RPS6KA5_ST	Q9H4A3	WNK1	O75582	RPS6KA5	S1285	A1284T	1284	Missense	proximal	-1	no	1.504	1.473	EPSD	COSMIC	1.456	Down-regulation
AGC_RSK_MSK_RPS6KA5_ST	Q9H4A3	WNK1	O75582	RPS6KA5	S1297	S1302A	1302	Missense	distal	5	no	1.548	1.547	EPSD	COSMIC	1.456	Down-regulation
AGC_RSK_MSK_RPS6KA5_ST	Q9H4A3	WNK1	O75582	RPS6KA5	S1297	S1302F	1302	Missense	distal	5	no	1.548	1.540	EPSD	COSMIC	1.456	Down-regulation
AGC_RSK_MSK_RPS6KA5_ST	Q9H4A3	WNK1	O75582	RPS6KA5	S1297	Q1304L	1304	Missense	distal	7	no	1.548	1.559	EPSD	COSMIC	1.456	Up-regulation
AGC_RSK_MSK_RPS6KA5_ST	Q9H4A3	WNK1	O75582	RPS6KA5	S1297	H1296Y	1296	Missense	proximal	-1	no	1.548	1.543	EPSD	COSMIC;CCLE	1.456	Down-regulation
AGC_RSK_MSK_RPS6KA5_ST	Q9H4A3	WNK1	O75582	RPS6KA5	S1297	S1297C	1297	Missense	central	0	yes	1.548	0.000	EPSD	COSMIC	1.456	Loss
AGC_RSK_MSK_RPS6KA5_ST	Q9H4A3	WNK1	O75582	RPS6KA5	S1299	S1302A	1302	Missense	distal	3	no	1.417	1.457	EPSD	COSMIC	1.456	Gain
AGC_RSK_MSK_RPS6KA5_ST	Q9H4A3	WNK1	O75582	RPS6KA5	S1300	S1302A	1302	Missense	proximal	2	no	1.518	1.523	EPSD	COSMIC	1.456	Up-regulation
AGC_RSK_MSK_RPS6KA5_ST	Q9H4A3	WNK1	O75582	RPS6KA5	S1300	S1302F	1302	Missense	proximal	2	no	1.518	1.492	EPSD	COSMIC	1.456	Down-regulation
AGC_RSK_MSK_RPS6KA5_ST	Q9H4A3	WNK1	O75582	RPS6KA5	S1300	Q1304L	1304	Missense	distal	4	no	1.518	1.513	EPSD	COSMIC	1.456	Down-regulation
AGC_RSK_MSK_RPS6KA5_ST	Q9H4A3	WNK1	O75582	RPS6KA5	S1300	Q1305K	1305	Missense	distal	5	no	1.518	1.524	EPSD	COSMIC	1.456	Up-regulation
AGC_RSK_MSK_RPS6KA5_ST	Q9H4A3	WNK1	O75582	RPS6KA5	S1300	H1296Y	1296	Missense	distal	-4	no	1.518	1.538	EPSD	COSMIC;CCLE	1.456	Up-regulation
AGC_RSK_MSK_RPS6KA5_ST	Q9H4A3	WNK1	O75582	RPS6KA5	S1300	S1297C	1297	Missense	distal	-3	no	1.518	1.413	EPSD	COSMIC	1.456	Loss
AGC_RSK_MSK_RPS6KA5_ST	Q9H4A3	WNK1	O75582	RPS6KA5	S1308	S1302A	1302	Missense	distal	-6	no	1.653	1.607	EPSD	COSMIC	1.456	Down-regulation
AGC_RSK_MSK_RPS6KA5_ST	Q9H4A3	WNK1	O75582	RPS6KA5	S1308	S1302F	1302	Missense	distal	-6	no	1.653	1.644	EPSD	COSMIC	1.456	Down-regulation
AGC_RSK_MSK_RPS6KA5_ST	Q9H4A3	WNK1	O75582	RPS6KA5	S1308	R1312H	1312	Missense	distal	4	no	1.653	1.625	EPSD	COSMIC	1.456	Down-regulation
AGC_RSK_MSK_RPS6KA5_ST	Q9H4A3	WNK1	O75582	RPS6KA5	S1308	Q1304L	1304	Missense	distal	-4	no	1.653	1.668	EPSD	COSMIC	1.456	Up-regulation
AGC_RSK_MSK_RPS6KA5_ST	Q9H4A3	WNK1	O75582	RPS6KA5	S1308	E1309Q	1309	Missense	proximal	1	no	1.653	1.650	EPSD	COSMIC	1.456	Down-regulation
AGC_RSK_MSK_RPS6KA5_ST	Q9H4A3	WNK1	O75582	RPS6KA5	S1308	Q1305K	1305	Missense	distal	-3	no	1.653	1.828	EPSD	COSMIC	1.456	Up-regulation
AGC_RSK_MSK_RPS6KA5_ST	Q9H4A3	WNK1	O75582	RPS6KA5	S1308	M1315V	1315	Missense	distal	7	no	1.653	1.670	EPSD	COSMIC	1.456	Up-regulation
AGC_RSK_MSK_RPS6KA5_ST	Q9H4A3	WNK1	O75582	RPS6KA5	S1528	S1528N	1528	Missense	central	0	yes	1.518	0.000	EPSD	COSMIC	1.456	Loss
AGC_RSK_MSK_RPS6KA5_ST	Q9H4A3	WNK1	O75582	RPS6KA5	S1528	S1535N	1535	Missense	distal	7	no	1.518	1.547	EPSD	COSMIC;GDSC;CCLE	1.456	Up-regulation
AGC_RSK_MSK_RPS6KA5_ST	Q9H4A3	WNK1	O75582	RPS6KA5	S1528	V1522M	1522	Missense	distal	-6	no	1.518	1.503	EPSD	COSMIC	1.456	Down-regulation
AGC_RSK_MSK_RPS6KA5_ST	Q9H4A3	WNK1	O75582	RPS6KA5	S1805	Q1799E	1799	Missense	distal	-6	no	1.717	1.733	EPSD	COSMIC;GDSC;CCLE	1.456	Up-regulation
AGC_RSK_MSK_RPS6KA5_ST	Q9H4A3	WNK1	O75582	RPS6KA5	S1805	M1808I	1808	Missense	distal	3	no	1.717	1.710	EPSD	COSMIC	1.456	Down-regulation
AGC_RSK_MSK_RPS6KA5_ST	Q9H4A3	WNK1	O75582	RPS6KA5	S1805	L1804F	1804	Missense	proximal	-1	no	1.717	1.711	EPSD	COSMIC	1.456	Down-regulation
AGC_RSK_MSK_RPS6KA5_ST	Q9H4A3	WNK1	O75582	RPS6KA5	S1838	S1838C	1838	Missense	central	0	yes	1.567	0.000	EPSD	COSMIC	1.456	Loss
AGC_RSK_MSK_RPS6KA5_ST	Q9H4A3	WNK1	O75582	RPS6KA5	S1838	S1838F	1838	Missense	central	0	yes	1.567	0.000	EPSD	COSMIC	1.456	Loss
AGC_RSK_MSK_RPS6KA5_ST	Q9H4A3	WNK1	O75582	RPS6KA5	S1838	S1838Y	1838	Missense	central	0	yes	1.567	0.000	EPSD	COSMIC	1.456	Loss
AGC_RSK_MSK_RPS6KA5_ST	Q9H4A3	WNK1	O75582	RPS6KA5	S1838	Q1834L	1834	Missense	distal	-4	no	1.567	1.583	EPSD	COSMIC	1.456	Up-regulation
AGC_RSK_MSK_RPS6KA5_ST	Q9H4A3	WNK1	O75582	RPS6KA5	S1838	P1833Q	1833	Missense	distal	-5	no	1.567	1.575	EPSD	COSMIC	1.456	Up-regulation
AGC_RSK_MSK_RPS6KA5_ST	Q9H4A3	WNK1	O75582	RPS6KA5	S1838	T1831K	1831	Missense	distal	-7	no	1.567	1.526	EPSD	COSMIC	1.456	Down-regulation
AGC_RSK_MSK_RPS6KA5_ST	Q9H4A3	WNK1	O75582	RPS6KA5	S1849	K1856T	1856	Missense	distal	7	no	1.601	1.640	EPSD	COSMIC	1.456	Up-regulation
AGC_RSK_MSK_RPS6KA5_ST	Q9H4A3	WNK1	O75582	RPS6KA5	S1849	V1854A	1854	Missense	distal	5	no	1.601	1.611	EPSD	COSMIC	1.456	Up-regulation
AGC_RSK_MSK_RPS6KA5_ST	Q9H4A3	WNK1	O75582	RPS6KA5	S1849	S1849N	1849	Missense	central	0	yes	1.601	0.000	EPSD	COSMIC	1.456	Loss
AGC_RSK_MSK_RPS6KA5_ST	Q9H4A3	WNK1	O75582	RPS6KA5	S1959	K1966E	1966	Missense	distal	7	no	2.597	2.619	EPSD	COSMIC	1.456	Up-regulation
AGC_RSK_MSK_RPS6KA5_ST	Q9H4A3	WNK1	O75582	RPS6KA5	S1959	G1956S	1956	Missense	distal	-3	no	2.597	2.721	EPSD	COSMIC	1.456	Up-regulation
AGC_RSK_MSK_RPS6KA5_ST	Q9H4A3	WNK1	O75582	RPS6KA5	S2051	Q2048K	2048	Missense	distal	-3	no	1.346	1.521	EPSD	COSMIC;GDSC;CCLE	1.456	Gain
AGC_RSK_MSK_RPS6KA5_ST	Q9H4A3	WNK1	O75582	RPS6KA5	S2121	P2119H	2119	Missense	proximal	-2	no	1.473	1.761	EPSD	COSMIC	1.456	Up-regulation
AGC_RSK_MSK_RPS6KA5_ST	Q9H4A3	WNK1	O75582	RPS6KA5	S2121	P2119R	2119	Missense	proximal	-2	no	1.473	3.339	EPSD	COSMIC	1.456	Up-regulation
AGC_RSK_MSK_RPS6KA5_ST	Q9H4A3	WNK1	O75582	RPS6KA5	S2121	A2118V	2118	Missense	distal	-3	no	1.473	1.053	EPSD	COSMIC	1.456	Loss
AGC_RSK_MSK_RPS6KA5_ST	Q9H4A3	WNK1	O75582	RPS6KA5	T2128	K2131N	2131	Missense	distal	3	no	2.040	2.010	EPSD	COSMIC	1.456	Down-regulation
AGC_RSK_MSK_RPS6KA5_ST	Q9H4A3	WNK1	O75582	RPS6KA5	T2128	S2135C	2135	Missense	distal	7	no	2.040	2.065	EPSD	COSMIC	1.456	Up-regulation
AGC_RSK_MSK_RPS6KA5_ST	Q9H4A3	WNK1	O75582	RPS6KA5	T2128	K2134R	2134	Missense	distal	6	no	2.040	2.036	EPSD	COSMIC	1.456	Down-regulation
AGC_RSK_MSK_RPS6KA5_ST	Q9H4A3	WNK1	O75582	RPS6KA5	S2136	K2131N	2131	Missense	distal	-5	no	1.576	1.563	EPSD	COSMIC	1.456	Down-regulation
AGC_RSK_MSK_RPS6KA5_ST	Q9H4A3	WNK1	O75582	RPS6KA5	S2136	S2135C	2135	Missense	proximal	-1	no	1.576	1.574	EPSD	COSMIC	1.456	Down-regulation
AGC_RSK_MSK_RPS6KA5_ST	Q9H4A3	WNK1	O75582	RPS6KA5	S2136	K2134R	2134	Missense	proximal	-2	no	1.576	2.929	EPSD	COSMIC	1.456	Up-regulation
AGC_RSK_MSK_RPS6KA5_ST	Q9H4A3	WNK1	O75582	RPS6KA5	S2139	P2146H	2146	Missense	distal	7	no	2.716	2.698	EPSD	COSMIC	1.456	Down-regulation
AGC_RSK_MSK_RPS6KA5_ST	Q9H4A3	WNK1	O75582	RPS6KA5	S2139	S2135C	2135	Missense	distal	-4	no	2.716	2.737	EPSD	COSMIC	1.456	Up-regulation
AGC_RSK_MSK_RPS6KA5_ST	Q9H4A3	WNK1	O75582	RPS6KA5	S2139	K2134R	2134	Missense	distal	-5	no	2.716	2.746	EPSD	COSMIC	1.456	Up-regulation
AGC_RSK_MSK_RPS6KA5_ST	Q9H4A3	WNK1	O75582	RPS6KA5	S2139	K2144E	2144	Missense	distal	5	no	2.716	2.707	EPSD	COSMIC;GDSC;CCLE	1.456	Down-regulation
AGC_RSK_MSK_RPS6KA5_ST	Q9H4A3	WNK1	O75582	RPS6KA5	S2140	P2146H	2146	Missense	distal	6	no	2.045	2.042	EPSD	COSMIC	1.456	Down-regulation
AGC_RSK_MSK_RPS6KA5_ST	Q9H4A3	WNK1	O75582	RPS6KA5	S2140	S2135C	2135	Missense	distal	-5	no	2.045	2.041	EPSD	COSMIC	1.456	Down-regulation
AGC_RSK_MSK_RPS6KA5_ST	Q9H4A3	WNK1	O75582	RPS6KA5	S2140	K2134R	2134	Missense	distal	-6	no	2.045	1.988	EPSD	COSMIC	1.456	Down-regulation
AGC_RSK_MSK_RPS6KA5_ST	Q9H4A3	WNK1	O75582	RPS6KA5	S2140	K2144E	2144	Missense	distal	4	no	2.045	2.015	EPSD	COSMIC;GDSC;CCLE	1.456	Down-regulation
AGC_RSK_MSK_RPS6KA5_ST	Q9H4A3	WNK1	O75582	RPS6KA5	S2270	R2267M	2267	Missense	distal	-3	no	3.662	2.648	EPSD	COSMIC	1.456	Down-regulation
AGC_RSK_MSK_RPS6KA5_ST	Q9H4A3	WNK1	O75582	RPS6KA5	S2286	G2289W	2289	Missense	distal	3	no	2.228	2.216	EPSD	COSMIC	1.456	Down-regulation
AGC_RSK_MSK_RPS6KA5_ST	Q9H4A3	WNK1	O75582	RPS6KA5	S2286	A2287E	2287	Missense	proximal	1	no	2.228	2.238	EPSD	COSMIC	1.456	Up-regulation
AGC_RSK_MSK_RPS6KA5_ST	Q9H4A3	WNK1	O75582	RPS6KA5	S2309	S2306F	2306	Missense	distal	-3	no	1.582	1.408	EPSD	COSMIC	1.456	Loss
AGC_RSK_MSK_RPS6KA5_ST	Q9H4A3	WNK1	O75582	RPS6KA5	S2372	G2376D	2376	Missense	distal	4	no	1.480	1.478	EPSD	COSMIC	1.456	Down-regulation
AGC_RSK_MSK_RPS6KA5_ST	Q9H4A3	WNK1	O75582	RPS6KA5	S2372	S2377T	2377	Missense	distal	5	no	1.480	1.464	EPSD	COSMIC	1.456	Down-regulation
AGC_RSK_MSK_RPS6KA5_ST	P11831	SRF	O75582	RPS6KA5	S16	A9T	9	Missense	distal	-7	no	2.719	2.765	EPSD	COSMIC	1.456	Up-regulation
AGC_RSK_MSK_RPS6KA5_ST	P11831	SRF	O75582	RPS6KA5	T159	R157C	157	Missense	proximal	-2	no	1.791	0.110	EPSD	COSMIC	1.456	Loss
AGC_RSK_MSK_RPS6KA5_ST	P11831	SRF	O75582	RPS6KA5	S237	T244P	244	Missense	distal	7	no	2.866	2.854	EPSD	COSMIC;GDSC;CCLE	1.456	Down-regulation
AGC_RSK_MSK_RPS6KA5_ST	P11831	SRF	O75582	RPS6KA5	S311	S316G	316	Missense	distal	5	no	1.567	1.562	EPSD	COSMIC	1.456	Down-regulation
AGC_RSK_MSK_RPS6KA5_ST	P11831	SRF	O75582	RPS6KA5	S311	P305L	305	Missense	distal	-6	no	1.567	1.560	EPSD	COSMIC	1.456	Down-regulation
AGC_RSK_MSK_RPS6KA5_ST	P11831	SRF	O75582	RPS6KA5	S311	S313G	313	Missense	proximal	2	no	1.567	1.545	EPSD	COSMIC	1.456	Down-regulation
AGC_RSK_MSK_RPS6KA5_ST	P11831	SRF	O75582	RPS6KA5	S316	S316G	316	Missense	central	0	yes	1.748	0.000	EPSD	COSMIC	1.456	Loss
AGC_RSK_MSK_RPS6KA5_ST	P11831	SRF	O75582	RPS6KA5	S316	S313G	313	Missense	distal	-3	no	1.748	1.625	EPSD	COSMIC	1.456	Down-regulation
AGC_RSK_MSK_RPS6KA5_ST	P11831	SRF	O75582	RPS6KA5	S316	T321A	321	Missense	distal	5	no	1.748	1.764	EPSD	COSMIC	1.456	Up-regulation
AGC_RSK_MSK_RPS6KA5_ST	P11831	SRF	O75582	RPS6KA5	S435	V430M	430	Missense	distal	-5	no	1.457	1.464	EPSD	COSMIC	1.456	Up-regulation
AGC_RSK_MSK_RPS6KA5_ST	P11831	SRF	O75582	RPS6KA5	S435	T429I	429	Missense	distal	-6	no	1.457	1.448	EPSD	COSMIC	1.456	Loss
AGC_RSK_MSK_RPS6KA5_ST	P11831	SRF	O75582	RPS6KA5	S435	A433T	433	Missense	proximal	-2	no	1.457	0.738	EPSD	COSMIC	1.456	Loss
AGC_RSK_MSK_RPS6KA5_ST	P11831	SRF	O75582	RPS6KA5	S435	A433V	433	Missense	proximal	-2	no	1.457	0.719	EPSD	COSMIC	1.456	Loss
AGC_RSK_MSK_RPS6KA5_ST	P11831	SRF	O75582	RPS6KA5	S435	A437S	437	Missense	proximal	2	no	1.457	1.451	EPSD	COSMIC	1.456	Loss
AGC_RSK_MSK_RPS6KA5_ST	P19419	ELK1	O75582	RPS6KA5	S303	P305S	305	Missense	proximal	2	no	1.903	1.931	EPSD	COSMIC	1.456	Up-regulation
AGC_RSK_MSK_RPS6KA5_ST	P19419	ELK1	O75582	RPS6KA5	S303	Q309R	309	Missense	distal	6	no	1.903	1.897	EPSD	COSMIC	1.456	Down-regulation
AGC_RSK_MSK_RPS6KA5_ST	P19419	ELK1	O75582	RPS6KA5	S304	P305S	305	Missense	proximal	1	no	1.739	1.743	EPSD	COSMIC	1.456	Up-regulation
AGC_RSK_MSK_RPS6KA5_ST	P19419	ELK1	O75582	RPS6KA5	S304	Q309R	309	Missense	distal	5	no	1.739	1.755	EPSD	COSMIC	1.456	Up-regulation
AGC_RSK_MSK_RPS6KA5_ST	P07101	TH	O75582	RPS6KA5	S19	R15S	15	Missense	distal	-4	no	2.445	2.539	EPSD	COSMIC	1.456	Up-regulation
AGC_RSK_MSK_RPS6KA5_ST	P07101	TH	O75582	RPS6KA5	S19	A17V	17	Missense	proximal	-2	no	2.445	1.707	EPSD	COSMIC;CCLE	1.456	Down-regulation
AGC_RSK_MSK_RPS6KA5_ST	P07101	TH	O75582	RPS6KA5	S19	S19C	19	Missense	central	0	yes	2.445	0.000	EPSD	COSMIC;GDSC;CCLE	1.456	Loss
AGC_RSK_MSK_RPS6KA5_ST	P07101	TH	O75582	RPS6KA5	S19	V18M	18	Missense	proximal	-1	no	2.445	2.463	EPSD	COSMIC	1.456	Up-regulation
AGC_RSK_MSK_RPS6KA5_ST	P07101	TH	O75582	RPS6KA5	S71	R64Q	64	Missense	distal	-7	no	3.730	3.795	EPSD	COSMIC;CCLE	1.456	Up-regulation
AGC_RSK_MSK_RPS6KA5_ST	P07101	TH	O75582	RPS6KA5	S509	S509F	509	Missense	central	0	yes	2.614	0.000	EPSD	COSMIC	1.456	Loss
AGC_RSK_MSK_RPS6KA5_ST	P07101	TH	O75582	RPS6KA5	S509	V506M	506	Missense	distal	-3	no	2.614	2.695	EPSD	COSMIC	1.456	Up-regulation
AGC_RSK_MSK_RPS6KA5_ST	P07101	TH	O75582	RPS6KA5	S509	P503H	503	Missense	distal	-6	no	2.614	2.597	EPSD	COSMIC	1.456	Down-regulation
TK_EGFR_EGFR_Y	P52735	VAV2	P00533	EGFR	Y142	S144N	144	Missense	proximal	2	no	11.200	12.758	PhosphoSitePlus;EPSD	COSMIC	6.466	Up-regulation
TK_EGFR_EGFR_Y	P52735	VAV2	P00533	EGFR	Y142	R143L	143	Missense	proximal	1	no	11.200	12.628	PhosphoSitePlus;EPSD	COSMIC	6.466	Up-regulation
TK_EGFR_EGFR_Y	P52735	VAV2	P00533	EGFR	Y159	P163L	163	Missense	distal	4	no	15.767	15.911	EPSD;PhosphoSitePlus	COSMIC;CCLE	6.466	Up-regulation
TK_EGFR_EGFR_Y	P52735	VAV2	P00533	EGFR	Y224	L230M	230	Missense	distal	6	no	6.534	7.471	EPSD	COSMIC	6.466	Up-regulation
TK_EGFR_EGFR_Y	P52735	VAV2	P00533	EGFR	Y224	R229Q	229	Missense	distal	5	no	6.534	6.719	EPSD	COSMIC	6.466	Up-regulation
TK_EGFR_EGFR_Y	P52735	VAV2	P00533	EGFR	Y549	T555A	555	Missense	distal	6	no	8.366	8.713	EPSD	COSMIC;CCLE	6.466	Up-regulation
TK_EGFR_EGFR_Y	Q8NFJ5	GPRC5A	P00533	EGFR	Y317	T315M	315	Missense	proximal	-2	no	9.261	6.864	EPSD;PhosphoSitePlus	COSMIC	6.466	Down-regulation
TK_EGFR_EGFR_Y	Q8NFJ5	GPRC5A	P00533	EGFR	Y320	T315M	315	Missense	distal	-5	no	8.152	7.396	PhosphoSitePlus;EPSD	COSMIC	6.466	Down-regulation
TK_EGFR_EGFR_Y	P29353	SHC1	P00533	EGFR	Y349	E343K	343	Missense	distal	-6	no	12.290	12.255	EPSD	COSMIC	6.466	Down-regulation
TK_EGFR_EGFR_Y	P29353	SHC1	P00533	EGFR	Y349	N351Y	351	Missense	proximal	2	no	12.290	9.194	EPSD	COSMIC	6.466	Down-regulation
TK_EGFR_EGFR_Y	P29353	SHC1	P00533	EGFR	Y349	P354L	354	Missense	distal	5	no	12.290	12.249	EPSD	COSMIC	6.466	Down-regulation
TK_EGFR_EGFR_Y	P29353	SHC1	P00533	EGFR	Y349	E343D	343	Missense	distal	-6	no	12.290	12.249	EPSD	COSMIC	6.466	Down-regulation
TK_EGFR_EGFR_Y	P29353	SHC1	P00533	EGFR	Y350	E343K	343	Missense	distal	-7	no	13.414	12.813	EPSD	COSMIC	6.466	Down-regulation
TK_EGFR_EGFR_Y	P29353	SHC1	P00533	EGFR	Y350	E357D	357	Missense	distal	7	no	13.414	13.271	EPSD	COSMIC;GDSC	6.466	Down-regulation
TK_EGFR_EGFR_Y	P29353	SHC1	P00533	EGFR	Y350	N351Y	351	Missense	proximal	1	no	13.414	13.845	EPSD	COSMIC	6.466	Up-regulation
TK_EGFR_EGFR_Y	P29353	SHC1	P00533	EGFR	Y350	P354L	354	Missense	distal	4	no	13.414	13.558	EPSD	COSMIC	6.466	Up-regulation
TK_EGFR_EGFR_Y	P29353	SHC1	P00533	EGFR	Y350	E343D	343	Missense	distal	-7	no	13.414	13.187	EPSD	COSMIC	6.466	Down-regulation
TK_EGFR_EGFR_Y	P29353	SHC1	P00533	EGFR	Y427	V430I	430	Missense	distal	3	no	16.057	15.890	EPSD	COSMIC	6.466	Down-regulation
TK_EGFR_EGFR_Y	P29353	SHC1	P00533	EGFR	Y427	S426C	426	Missense	proximal	-1	no	16.057	15.090	EPSD	COSMIC	6.466	Down-regulation
TK_EGFR_EGFR_Y	P29353	SHC1	P00533	EGFR	Y427	S426P	426	Missense	proximal	-1	no	16.057	16.106	EPSD	COSMIC	6.466	Up-regulation
TK_EGFR_EGFR_Y	Q01813	PFKP	P00533	EGFR	Y394	A398P	398	Missense	distal	4	no	6.278	6.595	EPSD	COSMIC	6.466	Gain
TK_EGFR_EGFR_Y	Q8IVM0	CCDC50	P00533	EGFR	Y145	R138H	138	Missense	distal	-7	no	6.831	6.449	EPSD	COSMIC	6.466	Loss
TK_EGFR_EGFR_Y	Q8IVM0	CCDC50	P00533	EGFR	Y145	D142N	142	Missense	distal	-3	no	6.831	5.497	EPSD	COSMIC;GDSC;CCLE	6.466	Loss
TK_EGFR_EGFR_Y	Q8IVM0	CCDC50	P00533	EGFR	Y145	M151T	151	Missense	distal	6	no	6.831	5.965	EPSD	COSMIC	6.466	Loss
TK_EGFR_EGFR_Y	Q8IVM0	CCDC50	P00533	EGFR	Y217	R223W	223	Missense	distal	6	no	8.637	8.651	EPSD;PhosphoSitePlus	COSMIC	6.466	Up-regulation
TK_EGFR_EGFR_Y	Q8IVM0	CCDC50	P00533	EGFR	Y217	E224D	224	Missense	distal	7	no	8.637	8.494	EPSD;PhosphoSitePlus	COSMIC;CCLE	6.466	Down-regulation
TK_EGFR_EGFR_Y	Q8IVM0	CCDC50	P00533	EGFR	Y217	K218R	218	Missense	proximal	1	no	8.637	7.815	EPSD;PhosphoSitePlus	COSMIC	6.466	Down-regulation
TK_EGFR_EGFR_Y	Q8IVM0	CCDC50	P00533	EGFR	Y217	R223Q	223	Missense	distal	6	no	8.637	8.845	EPSD;PhosphoSitePlus	COSMIC	6.466	Up-regulation
TK_EGFR_EGFR_Y	Q8IVM0	CCDC50	P00533	EGFR	Y279	D278G	278	Missense	proximal	-1	no	8.640	7.483	EPSD;PhosphoSitePlus	COSMIC	6.466	Down-regulation
TK_EGFR_EGFR_Y	Q8IVM0	CCDC50	P00533	EGFR	Y279	T283A	283	Missense	distal	4	no	8.640	8.456	EPSD;PhosphoSitePlus	COSMIC;CCLE	6.466	Down-regulation
TK_EGFR_EGFR_Y	Q8IVM0	CCDC50	P00533	EGFR	Y279	A277V	277	Missense	proximal	-2	no	8.640	7.665	EPSD;PhosphoSitePlus	COSMIC	6.466	Down-regulation
TK_EGFR_EGFR_Y	P00533	EGFR	P00533	EGFR	Y112	G109E	109	Missense	distal	-3	no	4.672	8.325	EPSD	COSMIC	6.466	Gain
TK_EGFR_EGFR_Y	P00533	EGFR	P00533	EGFR	Y764	V769M	769	Missense	distal	5	no	8.694	8.849	EPSD	COSMIC	6.466	Up-regulation
TK_EGFR_EGFR_Y	P00533	EGFR	P00533	EGFR	Y764	S768G	768	Missense	distal	4	no	8.694	9.023	EPSD	COSMIC	6.466	Up-regulation
TK_EGFR_EGFR_Y	P00533	EGFR	P00533	EGFR	Y764	D761N	761	Missense	distal	-3	no	8.694	7.360	EPSD	COSMIC	6.466	Down-regulation
TK_EGFR_EGFR_Y	P00533	EGFR	P00533	EGFR	Y764	Y764S	764	Missense	central	0	yes	8.694	0.000	EPSD	COSMIC	6.466	Loss
TK_EGFR_EGFR_Y	P00533	EGFR	P00533	EGFR	Y764	D770N	770	Missense	distal	6	no	8.694	9.441	EPSD	COSMIC	6.466	Up-regulation
TK_EGFR_EGFR_Y	P00533	EGFR	P00533	EGFR	Y764	I759V	759	Missense	distal	-5	no	8.694	8.627	EPSD	COSMIC	6.466	Down-regulation
TK_EGFR_EGFR_Y	P00533	EGFR	P00533	EGFR	Y764	D761G	761	Missense	distal	-3	no	8.694	6.135	EPSD	COSMIC	6.466	Loss
TK_EGFR_EGFR_Y	P00533	EGFR	P00533	EGFR	Y764	A767V	767	Missense	distal	3	no	8.694	8.836	EPSD	COSMIC	6.466	Up-regulation
TK_EGFR_EGFR_Y	P00533	EGFR	P00533	EGFR	Y764	E758G	758	Missense	distal	-6	no	8.694	8.587	EPSD	COSMIC	6.466	Down-regulation
TK_EGFR_EGFR_Y	P00533	EGFR	P00533	EGFR	Y764	K757N	757	Missense	distal	-7	no	8.694	8.747	EPSD	COSMIC	6.466	Up-regulation
TK_EGFR_EGFR_Y	P00533	EGFR	P00533	EGFR	Y764	V765E	765	Missense	proximal	1	no	8.694	7.540	EPSD	COSMIC	6.466	Down-regulation
TK_EGFR_EGFR_Y	P00533	EGFR	P00533	EGFR	Y764	S768N	768	Missense	distal	4	no	8.694	8.430	EPSD	COSMIC	6.466	Down-regulation
TK_EGFR_EGFR_Y	P00533	EGFR	P00533	EGFR	Y764	A763V	763	Missense	proximal	-1	no	8.694	7.190	EPSD	COSMIC	6.466	Down-regulation
TK_EGFR_EGFR_Y	P00533	EGFR	P00533	EGFR	Y764	V765M	765	Missense	proximal	1	no	8.694	7.470	EPSD	COSMIC	6.466	Down-regulation
TK_EGFR_EGFR_Y	P00533	EGFR	P00533	EGFR	Y764	S768C	768	Missense	distal	4	no	8.694	9.407	EPSD	COSMIC	6.466	Up-regulation
TK_EGFR_EGFR_Y	P00533	EGFR	P00533	EGFR	Y764	A763D	763	Missense	proximal	-1	no	8.694	9.982	EPSD	COSMIC	6.466	Up-regulation
TK_EGFR_EGFR_Y	P00533	EGFR	P00533	EGFR	Y764	S768T	768	Missense	distal	4	no	8.694	9.124	EPSD	COSMIC	6.466	Up-regulation
TK_EGFR_EGFR_Y	P00533	EGFR	P00533	EGFR	Y764	D761Y	761	Missense	distal	-3	no	8.694	6.680	EPSD	COSMIC	6.466	Down-regulation
TK_EGFR_EGFR_Y	P00533	EGFR	P00533	EGFR	Y764	L760P	760	Missense	distal	-4	no	8.694	9.197	EPSD	COSMIC	6.466	Up-regulation
TK_EGFR_EGFR_Y	P00533	EGFR	P00533	EGFR	Y764	V765L	765	Missense	proximal	1	no	8.694	8.137	EPSD	COSMIC	6.466	Down-regulation
TK_EGFR_EGFR_Y	P00533	EGFR	P00533	EGFR	Y764	E758K	758	Missense	distal	-6	no	8.694	8.659	EPSD	COSMIC	6.466	Down-regulation
TK_EGFR_EGFR_Y	P00533	EGFR	P00533	EGFR	Y764	L760F	760	Missense	distal	-4	no	8.694	10.564	EPSD	COSMIC	6.466	Up-regulation
TK_EGFR_EGFR_Y	P00533	EGFR	P00533	EGFR	Y764	M766Q	766	Missense	proximal	2	no	8.694	10.335	EPSD	COSMIC	6.466	Up-regulation
TK_EGFR_EGFR_Y	P00533	EGFR	P00533	EGFR	Y764	K757R	757	Missense	distal	-7	no	8.694	9.031	EPSD	COSMIC	6.466	Up-regulation
TK_EGFR_EGFR_Y	P00533	EGFR	P00533	EGFR	Y764	V765G	765	Missense	proximal	1	no	8.694	7.636	EPSD	COSMIC	6.466	Down-regulation
TK_EGFR_EGFR_Y	P00533	EGFR	P00533	EGFR	Y764	E758D	758	Missense	distal	-6	no	8.694	8.652	EPSD	COSMIC	6.466	Down-regulation
TK_EGFR_EGFR_Y	P00533	EGFR	P00533	EGFR	Y764	V769A	769	Missense	distal	5	no	8.694	8.869	EPSD	COSMIC	6.466	Up-regulation
TK_EGFR_EGFR_Y	P00533	EGFR	P00533	EGFR	Y764	M766L	766	Missense	proximal	2	no	8.694	7.047	EPSD	COSMIC	6.466	Down-regulation
TK_EGFR_EGFR_Y	P00533	EGFR	P00533	EGFR	Y764	M766I	766	Missense	proximal	2	no	8.694	8.733	EPSD	COSMIC	6.466	Up-regulation
TK_EGFR_EGFR_Y	P00533	EGFR	P00533	EGFR	Y764	S768V	768	Missense	distal	4	no	8.694	9.068	EPSD	COSMIC	6.466	Up-regulation
TK_EGFR_EGFR_Y	P00533	EGFR	P00533	EGFR	Y764	K757M	757	Missense	distal	-7	no	8.694	8.675	EPSD	COSMIC	6.466	Down-regulation
TK_EGFR_EGFR_Y	P00533	EGFR	P00533	EGFR	Y764	M766T	766	Missense	proximal	2	no	8.694	9.276	EPSD	COSMIC	6.466	Up-regulation
TK_EGFR_EGFR_Y	P00533	EGFR	P00533	EGFR	Y869	H870R	870	Missense	proximal	1	no	12.957	11.622	EPSD;PhosphoSitePlus	COSMIC	6.466	Down-regulation
TK_EGFR_EGFR_Y	P00533	EGFR	P00533	EGFR	Y869	A864T	864	Missense	distal	-5	no	12.957	12.899	EPSD;PhosphoSitePlus	COSMIC	6.466	Down-regulation
TK_EGFR_EGFR_Y	P00533	EGFR	P00533	EGFR	Y869	G873E	873	Missense	distal	4	no	12.957	12.556	EPSD;PhosphoSitePlus	COSMIC	6.466	Down-regulation
TK_EGFR_EGFR_Y	P00533	EGFR	P00533	EGFR	Y869	A871G	871	Missense	proximal	2	no	12.957	12.943	EPSD;PhosphoSitePlus	COSMIC	6.466	Down-regulation
TK_EGFR_EGFR_Y	P00533	EGFR	P00533	EGFR	Y869	A871V	871	Missense	proximal	2	no	12.957	11.645	EPSD;PhosphoSitePlus	COSMIC	6.466	Down-regulation
TK_EGFR_EGFR_Y	P00533	EGFR	P00533	EGFR	Y869	A864E	864	Missense	distal	-5	no	12.957	13.394	EPSD;PhosphoSitePlus	COSMIC	6.466	Up-regulation
TK_EGFR_EGFR_Y	P00533	EGFR	P00533	EGFR	Y869	K867T	867	Missense	proximal	-2	no	12.957	12.924	EPSD;PhosphoSitePlus	COSMIC	6.466	Down-regulation
TK_EGFR_EGFR_Y	P00533	EGFR	P00533	EGFR	Y869	A871E	871	Missense	proximal	2	no	12.957	14.589	EPSD;PhosphoSitePlus	COSMIC	6.466	Up-regulation
TK_EGFR_EGFR_Y	P00533	EGFR	P00533	EGFR	Y869	E868K	868	Missense	proximal	-1	no	12.957	10.558	EPSD;PhosphoSitePlus	COSMIC	6.466	Down-regulation
TK_EGFR_EGFR_Y	P00533	EGFR	P00533	EGFR	Y869	G863D	863	Missense	distal	-6	no	12.957	13.022	EPSD;PhosphoSitePlus	COSMIC	6.466	Up-regulation
TK_EGFR_EGFR_Y	P00533	EGFR	P00533	EGFR	Y869	E866D	866	Missense	distal	-3	no	12.957	11.862	EPSD;PhosphoSitePlus	COSMIC;GDSC;CCLE	6.466	Down-regulation
TK_EGFR_EGFR_Y	P00533	EGFR	P00533	EGFR	Y869	L862Q	862	Missense	distal	-7	no	12.957	13.053	EPSD;PhosphoSitePlus	COSMIC	6.466	Up-regulation
TK_EGFR_EGFR_Y	P00533	EGFR	P00533	EGFR	Y869	A871T	871	Missense	proximal	2	no	12.957	12.525	EPSD;PhosphoSitePlus	COSMIC	6.466	Down-regulation
TK_EGFR_EGFR_Y	P00533	EGFR	P00533	EGFR	Y869	L862V	862	Missense	distal	-7	no	12.957	12.589	EPSD;PhosphoSitePlus	COSMIC	6.466	Down-regulation
TK_EGFR_EGFR_Y	P00533	EGFR	P00533	EGFR	Y869	H870N	870	Missense	proximal	1	no	12.957	13.071	EPSD;PhosphoSitePlus	COSMIC	6.466	Up-regulation
TK_EGFR_EGFR_Y	P00533	EGFR	P00533	EGFR	Y869	E868G	868	Missense	proximal	-1	no	12.957	11.874	EPSD;PhosphoSitePlus	COSMIC	6.466	Down-regulation
TK_EGFR_EGFR_Y	P00533	EGFR	P00533	EGFR	Y869	G873Q	873	Missense	distal	4	no	12.957	12.802	EPSD;PhosphoSitePlus	COSMIC	6.466	Down-regulation
TK_EGFR_EGFR_Y	P00533	EGFR	P00533	EGFR	Y869	E872K	872	Missense	distal	3	no	12.957	12.798	EPSD;PhosphoSitePlus	COSMIC	6.466	Down-regulation
TK_EGFR_EGFR_Y	P00533	EGFR	P00533	EGFR	Y869	G863S	863	Missense	distal	-6	no	12.957	13.000	EPSD;PhosphoSitePlus	COSMIC	6.466	Up-regulation
TK_EGFR_EGFR_Y	P00533	EGFR	P00533	EGFR	Y869	E868D	868	Missense	proximal	-1	no	12.957	13.031	EPSD;PhosphoSitePlus	COSMIC	6.466	Up-regulation
TK_EGFR_EGFR_Y	P00533	EGFR	P00533	EGFR	Y869	G874D	874	Missense	distal	5	no	12.957	12.961	EPSD;PhosphoSitePlus	COSMIC	6.466	Up-regulation
TK_EGFR_EGFR_Y	P00533	EGFR	P00533	EGFR	Y869	G874S	874	Missense	distal	5	no	12.957	13.028	EPSD;PhosphoSitePlus	COSMIC	6.466	Up-regulation
TK_EGFR_EGFR_Y	P00533	EGFR	P00533	EGFR	Y869	H870Y	870	Missense	proximal	1	no	12.957	13.501	EPSD;PhosphoSitePlus	COSMIC	6.466	Up-regulation
TK_EGFR_EGFR_Y	P00533	EGFR	P00533	EGFR	Y869	L862R	862	Missense	distal	-7	no	12.957	13.608	EPSD;PhosphoSitePlus	COSMIC	6.466	Up-regulation
TK_EGFR_EGFR_Y	P00533	EGFR	P00533	EGFR	Y869	Y869C	869	Missense	central	0	yes	12.957	0.000	EPSD;PhosphoSitePlus	COSMIC	6.466	Loss
TK_EGFR_EGFR_Y	P00533	EGFR	P00533	EGFR	Y869	L862P	862	Missense	distal	-7	no	12.957	13.037	EPSD;PhosphoSitePlus	COSMIC	6.466	Up-regulation
TK_EGFR_EGFR_Y	P00533	EGFR	P00533	EGFR	Y869	E865K	865	Missense	distal	-4	no	12.957	10.845	EPSD;PhosphoSitePlus	COSMIC	6.466	Down-regulation
TK_EGFR_EGFR_Y	P00533	EGFR	P00533	EGFR	Y869	E866V	866	Missense	distal	-3	no	12.957	8.380	EPSD;PhosphoSitePlus	COSMIC	6.466	Down-regulation
TK_EGFR_EGFR_Y	P00533	EGFR	P00533	EGFR	Y869	E866G	866	Missense	distal	-3	no	12.957	9.303	EPSD;PhosphoSitePlus	COSMIC	6.466	Down-regulation
TK_EGFR_EGFR_Y	P00533	EGFR	P00533	EGFR	Y869	K875R	875	Missense	distal	6	no	12.957	12.553	EPSD;PhosphoSitePlus	COSMIC	6.466	Down-regulation
TK_EGFR_EGFR_Y	P00533	EGFR	P00533	EGFR	Y869	G873R	873	Missense	distal	4	no	12.957	13.418	EPSD;PhosphoSitePlus	COSMIC	6.466	Up-regulation
TK_EGFR_EGFR_Y	P00533	EGFR	P00533	EGFR	Y869	E868V	868	Missense	proximal	-1	no	12.957	10.240	EPSD;PhosphoSitePlus	COSMIC	6.466	Down-regulation
TK_EGFR_EGFR_Y	P00533	EGFR	P00533	EGFR	Y869	E866Q	866	Missense	distal	-3	no	12.957	9.998	EPSD;PhosphoSitePlus	COSMIC	6.466	Down-regulation
TK_EGFR_EGFR_Y	P00533	EGFR	P00533	EGFR	Y869	G863V	863	Missense	distal	-6	no	12.957	13.013	EPSD;PhosphoSitePlus	COSMIC	6.466	Up-regulation
TK_EGFR_EGFR_Y	P00533	EGFR	P00533	EGFR	Y998	F997L	997	Missense	proximal	-1	no	7.773	7.493	EPSD	COSMIC	6.466	Down-regulation
TK_EGFR_EGFR_Y	P00533	EGFR	P00533	EGFR	Y998	M1002V	1002	Missense	distal	4	no	7.773	7.616	EPSD	COSMIC	6.466	Down-regulation
TK_EGFR_EGFR_Y	P00533	EGFR	P00533	EGFR	Y998	E1004K	1004	Missense	distal	6	no	7.773	7.814	EPSD	COSMIC	6.466	Up-regulation
TK_EGFR_EGFR_Y	P00533	EGFR	P00533	EGFR	Y998	M1002I	1002	Missense	distal	4	no	7.773	7.588	EPSD	COSMIC	6.466	Down-regulation
TK_EGFR_EGFR_Y	P00533	EGFR	P00533	EGFR	Y998	R999C	999	Missense	proximal	1	no	7.773	9.600	EPSD	COSMIC	6.466	Up-regulation
TK_EGFR_EGFR_Y	P00533	EGFR	P00533	EGFR	Y1016	P1019S	1019	Missense	distal	3	no	9.841	10.209	PhosphoSitePlus;EPSD	COSMIC	6.466	Up-regulation
TK_EGFR_EGFR_Y	P00533	EGFR	P00533	EGFR	Y1016	D1014G	1014	Missense	proximal	-2	no	9.841	6.603	PhosphoSitePlus;EPSD	COSMIC	6.466	Down-regulation
TK_EGFR_EGFR_Y	P00533	EGFR	P00533	EGFR	Y1016	G1022S	1022	Missense	distal	6	no	9.841	9.593	PhosphoSitePlus;EPSD	COSMIC	6.466	Down-regulation
TK_EGFR_EGFR_Y	P00533	EGFR	P00533	EGFR	Y1016	D1014V	1014	Missense	proximal	-2	no	9.841	6.910	PhosphoSitePlus;EPSD	COSMIC	6.466	Down-regulation
TK_EGFR_EGFR_Y	P00533	EGFR	P00533	EGFR	Y1016	V1011E	1011	Missense	distal	-5	no	9.841	11.242	PhosphoSitePlus;EPSD	COSMIC	6.466	Up-regulation
TK_EGFR_EGFR_Y	P00533	EGFR	P00533	EGFR	Y1016	D1014N	1014	Missense	proximal	-2	no	9.841	9.889	PhosphoSitePlus;EPSD	COSMIC	6.466	Up-regulation
TK_EGFR_EGFR_Y	P00533	EGFR	P00533	EGFR	Y1016	V1010L	1010	Missense	distal	-6	no	9.841	9.821	PhosphoSitePlus;EPSD	COSMIC	6.466	Down-regulation
TK_EGFR_EGFR_Y	P00533	EGFR	P00533	EGFR	Y1016	V1011M	1011	Missense	distal	-5	no	9.841	9.992	PhosphoSitePlus;EPSD	COSMIC;GDSC;CCLE	6.466	Up-regulation
TK_EGFR_EGFR_Y	P00533	EGFR	P00533	EGFR	Y1016	D1012H	1012	Missense	distal	-4	no	9.841	8.367	PhosphoSitePlus;EPSD	COSMIC	6.466	Down-regulation
TK_EGFR_EGFR_Y	P00533	EGFR	P00533	EGFR	Y1016	E1015K	1015	Missense	proximal	-1	no	9.841	7.442	PhosphoSitePlus;EPSD	COSMIC	6.466	Down-regulation
TK_EGFR_EGFR_Y	P00533	EGFR	P00533	EGFR	Y1016	D1009Y	1009	Missense	distal	-7	no	9.841	8.933	PhosphoSitePlus;EPSD	COSMIC	6.466	Down-regulation
TK_EGFR_EGFR_Y	P00533	EGFR	P00533	EGFR	Y1016	Q1020H	1020	Missense	distal	4	no	9.841	10.556	PhosphoSitePlus;EPSD	COSMIC	6.466	Up-regulation
TK_EGFR_EGFR_Y	P00533	EGFR	P00533	EGFR	Y1016	V1010M	1010	Missense	distal	-6	no	9.841	9.835	PhosphoSitePlus;EPSD	COSMIC	6.466	Down-regulation
TK_EGFR_EGFR_Y	P00533	EGFR	P00533	EGFR	Y1092	I1093M	1093	Missense	proximal	1	no	10.686	11.126	EPSD;PhosphoSitePlus	COSMIC	6.466	Up-regulation
TK_EGFR_EGFR_Y	P00533	EGFR	P00533	EGFR	Y1092	N1094Y	1094	Missense	proximal	2	no	10.686	7.590	EPSD;PhosphoSitePlus	COSMIC	6.466	Down-regulation
TK_EGFR_EGFR_Y	P00533	EGFR	P00533	EGFR	Y1092	P1088S	1088	Missense	distal	-4	no	10.686	11.344	EPSD;PhosphoSitePlus	COSMIC	6.466	Up-regulation
TK_EGFR_EGFR_Y	P00533	EGFR	P00533	EGFR	Y1110	N1107K	1107	Missense	distal	-3	no	11.780	11.503	EPSD;PhosphoSitePlus	COSMIC	6.466	Down-regulation
TK_EGFR_EGFR_Y	P00533	EGFR	P00533	EGFR	Y1110	V1109I	1109	Missense	proximal	-1	no	11.780	13.399	EPSD;PhosphoSitePlus	COSMIC	6.466	Up-regulation
TK_EGFR_EGFR_Y	P00533	EGFR	P00533	EGFR	Y1110	Q1106L	1106	Missense	distal	-4	no	11.780	9.443	EPSD;PhosphoSitePlus	COSMIC	6.466	Down-regulation
TK_EGFR_EGFR_Y	P00533	EGFR	P00533	EGFR	Y1110	N1112S	1112	Missense	proximal	2	no	11.780	10.223	EPSD;PhosphoSitePlus	COSMIC	6.466	Down-regulation
TK_EGFR_EGFR_Y	P00533	EGFR	P00533	EGFR	Y1110	V1105M	1105	Missense	distal	-5	no	11.780	11.931	EPSD;PhosphoSitePlus	COSMIC	6.466	Up-regulation
TK_EGFR_EGFR_Y	P00533	EGFR	P00533	EGFR	Y1110	P1108R	1108	Missense	proximal	-2	no	11.780	9.411	EPSD;PhosphoSitePlus	COSMIC	6.466	Down-regulation
TK_EGFR_EGFR_Y	P00533	EGFR	P00533	EGFR	Y1110	H1111N	1111	Missense	proximal	1	no	11.780	11.894	EPSD;PhosphoSitePlus	COSMIC	6.466	Up-regulation
TK_EGFR_EGFR_Y	P00533	EGFR	P00533	EGFR	Y1125	A1118T	1118	Missense	distal	-7	no	11.851	11.752	EPSD	COSMIC;GDSC;CCLE	6.466	Down-regulation
TK_EGFR_EGFR_Y	P00533	EGFR	P00533	EGFR	Y1125	H1124Q	1124	Missense	proximal	-1	no	11.851	10.529	EPSD	COSMIC;CCLE	6.466	Down-regulation
TK_EGFR_EGFR_Y	P00533	EGFR	P00533	EGFR	Y1125	S1130G	1130	Missense	distal	5	no	11.851	11.780	EPSD	COSMIC;GDSC;CCLE	6.466	Down-regulation
TK_EGFR_EGFR_Y	P00533	EGFR	P00533	EGFR	Y1125	H1129Y	1129	Missense	distal	4	no	11.851	11.888	EPSD	COSMIC	6.466	Up-regulation
TK_EGFR_EGFR_Y	P00533	EGFR	P00533	EGFR	Y1125	S1130R	1130	Missense	distal	5	no	11.851	11.679	EPSD	COSMIC	6.466	Down-regulation
TK_EGFR_EGFR_Y	P00533	EGFR	P00533	EGFR	Y1125	A1118S	1118	Missense	distal	-7	no	11.851	11.424	EPSD	COSMIC	6.466	Down-regulation
TK_EGFR_EGFR_Y	P00533	EGFR	P00533	EGFR	Y1125	S1120N	1120	Missense	distal	-5	no	11.851	11.843	EPSD	COSMIC	6.466	Down-regulation
TK_EGFR_EGFR_Y	P00533	EGFR	P00533	EGFR	Y1125	D1127N	1127	Missense	proximal	2	no	11.851	12.038	EPSD	COSMIC;GDSC;CCLE	6.466	Up-regulation
TK_EGFR_EGFR_Y	P00533	EGFR	P00533	EGFR	Y1138	E1137K	1137	Missense	proximal	-1	no	10.965	8.566	EPSD	COSMIC	6.466	Down-regulation
TK_EGFR_EGFR_Y	P00533	EGFR	P00533	EGFR	Y1138	P1136L	1136	Missense	proximal	-2	no	10.965	5.544	EPSD	COSMIC	6.466	Loss
TK_EGFR_EGFR_Y	P00533	EGFR	P00533	EGFR	Y1138	N1140S	1140	Missense	proximal	2	no	10.965	9.408	EPSD	COSMIC	6.466	Down-regulation
TK_EGFR_EGFR_Y	P00533	EGFR	P00533	EGFR	Y1138	P1136A	1136	Missense	proximal	-2	no	10.965	10.088	EPSD	COSMIC	6.466	Down-regulation
TK_EGFR_EGFR_Y	P00533	EGFR	P00533	EGFR	Y1172	P1170S	1170	Missense	proximal	-2	no	9.835	10.097	EPSD;PhosphoSitePlus	COSMIC	6.466	Up-regulation
TK_EGFR_EGFR_Y	P00533	EGFR	P00533	EGFR	Y1172	Q1174R	1174	Missense	proximal	2	no	9.835	7.916	EPSD;PhosphoSitePlus	COSMIC;CCLE	6.466	Down-regulation
TK_EGFR_EGFR_Y	P00533	EGFR	P00533	EGFR	Y1172	L1167V	1167	Missense	distal	-5	no	9.835	9.723	EPSD;PhosphoSitePlus	COSMIC	6.466	Down-regulation
TK_EGFR_EGFR_Y	P00533	EGFR	P00533	EGFR	Y1172	D1175V	1175	Missense	distal	3	no	9.835	10.382	EPSD;PhosphoSitePlus	COSMIC	6.466	Up-regulation
TK_EGFR_EGFR_Y	P00533	EGFR	P00533	EGFR	Y1172	D1168Y	1168	Missense	distal	-4	no	9.835	8.386	EPSD;PhosphoSitePlus	COSMIC	6.466	Down-regulation
TK_EGFR_EGFR_Y	P35222	CTNNB1	P00533	EGFR	Y30	Q28E	28	Missense	proximal	-2	no	6.275	8.285	EPSD	COSMIC	6.466	Gain
TK_EGFR_EGFR_Y	P35222	CTNNB1	P00533	EGFR	Y30	G34L	34	Missense	distal	4	no	6.275	6.652	EPSD	COSMIC	6.466	Gain
TK_EGFR_EGFR_Y	P35222	CTNNB1	P00533	EGFR	Y30	S33L	33	Missense	distal	3	no	6.275	6.529	EPSD	COSMIC;CCLE	6.466	Gain
TK_EGFR_EGFR_Y	P35222	CTNNB1	P00533	EGFR	Y30	S23R	23	Missense	distal	-7	no	6.275	6.600	EPSD	COSMIC	6.466	Gain
TK_EGFR_EGFR_Y	P35222	CTNNB1	P00533	EGFR	Y30	W25R	25	Missense	distal	-5	no	6.275	7.602	EPSD	COSMIC	6.466	Gain
TK_EGFR_EGFR_Y	P35222	CTNNB1	P00533	EGFR	Y30	W25L	25	Missense	distal	-5	no	6.275	7.321	EPSD	COSMIC	6.466	Gain
TK_EGFR_EGFR_Y	P35222	CTNNB1	P00533	EGFR	Y30	I35N	35	Missense	distal	5	no	6.275	6.467	EPSD	COSMIC	6.466	Gain
TK_EGFR_EGFR_Y	P35222	CTNNB1	P00533	EGFR	Y30	L31Q	31	Missense	proximal	1	no	6.275	6.670	EPSD	COSMIC	6.466	Gain
TK_EGFR_EGFR_Y	P35222	CTNNB1	P00533	EGFR	Y30	G34C	34	Missense	distal	4	no	6.275	6.659	EPSD	COSMIC	6.466	Gain
TK_EGFR_EGFR_Y	P35222	CTNNB1	P00533	EGFR	Y654	T653R	653	Missense	proximal	-1	no	6.536	7.030	EPSD;PhosphoSitePlus	COSMIC	6.466	Up-regulation
TK_EGFR_EGFR_Y	P35222	CTNNB1	P00533	EGFR	Y654	A657T	657	Missense	distal	3	no	6.536	6.293	EPSD;PhosphoSitePlus	COSMIC	6.466	Loss
TK_EGFR_EGFR_Y	P35222	CTNNB1	P00533	EGFR	Y654	R647G	647	Missense	distal	-7	no	6.536	6.256	EPSD;PhosphoSitePlus	COSMIC	6.466	Loss
TK_EGFR_EGFR_Y	P35222	CTNNB1	P00533	EGFR	Y654	R661Q	661	Missense	distal	7	no	6.536	6.520	EPSD;PhosphoSitePlus	COSMIC;CCLE	6.466	Down-regulation
TK_EGFR_EGFR_Y	P35222	CTNNB1	P00533	EGFR	Y654	A652V	652	Missense	proximal	-2	no	6.536	5.560	EPSD;PhosphoSitePlus	COSMIC	6.466	Loss
TK_EGFR_EGFR_Y	P35222	CTNNB1	P00533	EGFR	Y654	R661L	661	Missense	distal	7	no	6.536	6.239	EPSD;PhosphoSitePlus	COSMIC	6.466	Loss
TK_EGFR_EGFR_Y	P35222	CTNNB1	P00533	EGFR	Y654	R661P	661	Missense	distal	7	no	6.536	6.529	EPSD;PhosphoSitePlus	COSMIC	6.466	Down-regulation
TK_EGFR_EGFR_Y	P35222	CTNNB1	P00533	EGFR	Y654	V658F	658	Missense	distal	4	no	6.536	6.907	EPSD;PhosphoSitePlus	COSMIC;GDSC	6.466	Up-regulation
TK_EGFR_EGFR_Y	P35222	CTNNB1	P00533	EGFR	Y654	L659S	659	Missense	distal	5	no	6.536	6.804	EPSD;PhosphoSitePlus	COSMIC	6.466	Up-regulation
TK_EGFR_EGFR_Y	P35222	CTNNB1	P00533	EGFR	Y654	V651F	651	Missense	distal	-3	no	6.536	6.768	EPSD;PhosphoSitePlus	COSMIC	6.466	Up-regulation
TK_EGFR_EGFR_Y	P35222	CTNNB1	P00533	EGFR	Y654	A656T	656	Missense	proximal	2	no	6.536	6.104	EPSD;PhosphoSitePlus	COSMIC	6.466	Loss
TK_EGFR_EGFR_Y	P35222	CTNNB1	P00533	EGFR	Y716	Y716C	716	Missense	central	0	yes	7.581	0.000	EPSD	COSMIC	6.466	Loss
TK_EGFR_EGFR_Y	P35222	CTNNB1	P00533	EGFR	Y716	H720P	720	Missense	distal	4	no	7.581	7.254	EPSD	COSMIC	6.466	Down-regulation
TK_EGFR_EGFR_Y	P35222	CTNNB1	P00533	EGFR	Y716	R717C	717	Missense	proximal	1	no	7.581	9.409	EPSD	COSMIC	6.466	Up-regulation
TK_EGFR_EGFR_Y	P35222	CTNNB1	P00533	EGFR	Y716	S715R	715	Missense	proximal	-1	no	7.581	7.327	EPSD	COSMIC	6.466	Down-regulation
TK_EGFR_EGFR_Y	P35222	CTNNB1	P00533	EGFR	Y716	D712N	712	Missense	distal	-4	no	7.581	8.673	EPSD	COSMIC	6.466	Up-regulation
TK_EGFR_EGFR_Y	P35222	CTNNB1	P00533	EGFR	Y716	P714S	714	Missense	proximal	-2	no	7.581	7.844	EPSD	COSMIC	6.466	Up-regulation
TK_EGFR_EGFR_Y	P35222	CTNNB1	P00533	EGFR	Y716	Y709C	709	Missense	distal	-7	no	7.581	7.819	EPSD	COSMIC	6.466	Up-regulation
TK_EGFR_EGFR_Y	P35222	CTNNB1	P00533	EGFR	Y716	R710C	710	Missense	distal	-6	no	7.581	7.608	EPSD	COSMIC	6.466	Up-regulation
TK_EGFR_EGFR_Y	P35222	CTNNB1	P00533	EGFR	Y716	G723S	723	Missense	distal	7	no	7.581	7.259	EPSD	COSMIC	6.466	Down-regulation
TK_EGFR_EGFR_Y	P19174	PLCG1	P00533	EGFR	Y472	E473K	473	Missense	proximal	1	no	10.012	10.004	EPSD	COSMIC	6.466	Down-regulation
TK_EGFR_EGFR_Y	P19174	PLCG1	P00533	EGFR	Y506	H508Q	508	Missense	proximal	2	no	6.186	6.871	EPSD	COSMIC	6.466	Gain
TK_EGFR_EGFR_Y	P19174	PLCG1	P00533	EGFR	Y669	W668G	668	Missense	proximal	-1	no	5.795	8.939	EPSD	COSMIC	6.466	Gain
TK_EGFR_EGFR_Y	P19174	PLCG1	P00533	EGFR	Y702	I704M	704	Missense	proximal	2	no	7.167	7.128	EPSD	COSMIC	6.466	Down-regulation
TK_EGFR_EGFR_Y	P19174	PLCG1	P00533	EGFR	Y702	R707L	707	Missense	distal	5	no	7.167	7.071	EPSD	COSMIC	6.466	Down-regulation
TK_EGFR_EGFR_Y	P19174	PLCG1	P00533	EGFR	Y702	S705C	705	Missense	distal	3	no	7.167	7.053	EPSD	COSMIC	6.466	Down-regulation
TK_EGFR_EGFR_Y	P19174	PLCG1	P00533	EGFR	Y771	Y775F	775	Missense	distal	4	no	10.925	10.744	PhosphoSitePlus;EPSD	COSMIC	6.466	Down-regulation
TK_EGFR_EGFR_Y	P19174	PLCG1	P00533	EGFR	Y1253	G1247A	1247	Missense	distal	-6	no	11.096	11.200	EPSD	COSMIC	6.466	Up-regulation
TK_EGFR_EGFR_Y	P19174	PLCG1	P00533	EGFR	Y1253	P1256Q	1256	Missense	distal	3	no	11.096	11.338	EPSD	COSMIC	6.466	Up-regulation
TK_EGFR_EGFR_Y	P19174	PLCG1	P00533	EGFR	Y1253	E1258K	1258	Missense	distal	5	no	11.096	11.084	EPSD	COSMIC	6.466	Down-regulation
TK_EGFR_EGFR_Y	P19174	PLCG1	P00533	EGFR	Y1253	Q1254K	1254	Missense	proximal	1	no	11.096	10.095	EPSD	COSMIC	6.466	Down-regulation
TK_EGFR_EGFR_Y	Q05397	PTK2	P00533	EGFR	Y397	S390A	390	Missense	distal	-7	no	17.838	18.266	EPSD	COSMIC	6.466	Up-regulation
TK_EGFR_EGFR_Y	Q05397	PTK2	P00533	EGFR	Y397	D402V	402	Missense	distal	5	no	17.838	17.745	EPSD	COSMIC	6.466	Down-regulation
TK_EGFR_EGFR_Y	Q05397	PTK2	P00533	EGFR	Y397	E404A	404	Missense	distal	7	no	17.838	17.846	EPSD	COSMIC	6.466	Up-regulation
TK_EGFR_EGFR_Y	Q05397	PTK2	P00533	EGFR	Y397	V391A	391	Missense	distal	-6	no	17.838	17.887	EPSD	COSMIC	6.466	Up-regulation
TK_EGFR_EGFR_Y	Q05397	PTK2	P00533	EGFR	Y407	D402V	402	Missense	distal	-5	no	12.749	11.716	EPSD	COSMIC	6.466	Down-regulation
TK_EGFR_EGFR_Y	Q05397	PTK2	P00533	EGFR	Y407	D405G	405	Missense	proximal	-2	no	12.749	9.511	EPSD	COSMIC	6.466	Down-regulation
TK_EGFR_EGFR_Y	Q05397	PTK2	P00533	EGFR	Y407	R413S	413	Missense	distal	6	no	12.749	12.670	EPSD	COSMIC	6.466	Down-regulation
TK_EGFR_EGFR_Y	Q05397	PTK2	P00533	EGFR	Y407	E404A	404	Missense	distal	-3	no	12.749	9.456	EPSD	COSMIC	6.466	Down-regulation
TK_EGFR_EGFR_Y	Q05397	PTK2	P00533	EGFR	Y577	A579V	579	Missense	proximal	2	no	6.649	5.337	EPSD	COSMIC	6.466	Loss
TK_EGFR_EGFR_Y	Q05397	PTK2	P00533	EGFR	Y742	S745Y	745	Missense	distal	3	no	7.192	6.700	EPSD	COSMIC	6.466	Down-regulation
TK_EGFR_EGFR_Y	Q05397	PTK2	P00533	EGFR	Y898	E900V	900	Missense	proximal	2	no	6.638	3.694	EPSD	COSMIC	6.466	Loss
TK_EGFR_EGFR_Y	Q05397	PTK2	P00533	EGFR	Y925	G930C	930	Missense	distal	5	no	10.595	10.596	EPSD	COSMIC	6.466	Up-regulation
TK_EGFR_EGFR_Y	Q05397	PTK2	P00533	EGFR	Y925	D918G	918	Missense	distal	-7	no	10.595	10.280	EPSD	COSMIC	6.466	Down-regulation
TK_EGFR_EGFR_Y	Q05397	PTK2	P00533	EGFR	Y925	E926K	926	Missense	proximal	1	no	10.595	10.587	EPSD	COSMIC	6.466	Down-regulation
TK_EGFR_EGFR_Y	Q05397	PTK2	P00533	EGFR	Y925	Y925C	925	Missense	central	0	yes	10.595	0.000	EPSD	COSMIC	6.466	Loss
TK_EGFR_EGFR_Y	Q05397	PTK2	P00533	EGFR	Y925	R919L	919	Missense	distal	-6	no	10.595	10.603	EPSD	COSMIC	6.466	Up-regulation
TK_EGFR_EGFR_Y	Q05397	PTK2	P00533	EGFR	Y925	R919Q	919	Missense	distal	-6	no	10.595	10.602	EPSD	COSMIC	6.466	Up-regulation
TK_EGFR_EGFR_Y	P12004	PCNA	P00533	EGFR	Y211	L205V	205	Missense	distal	-6	no	7.900	7.920	PhosphoSitePlus	COSMIC	6.466	Up-regulation
TK_EGFR_EGFR_Y	Q13480	GAB1	P00533	EGFR	Y285	T289I	289	Missense	distal	4	no	10.197	10.113	EPSD;PhosphoSitePlus	COSMIC	6.466	Down-regulation
TK_EGFR_EGFR_Y	Q13480	GAB1	P00533	EGFR	Y307	D308G	308	Missense	proximal	1	no	7.462	7.056	EPSD	COSMIC	6.466	Down-regulation
TK_EGFR_EGFR_Y	Q13480	GAB1	P00533	EGFR	Y307	P311A	311	Missense	distal	4	no	7.462	7.145	EPSD	COSMIC	6.466	Down-regulation
TK_EGFR_EGFR_Y	Q13480	GAB1	P00533	EGFR	Y307	D308V	308	Missense	proximal	1	no	7.462	8.114	EPSD	COSMIC	6.466	Up-regulation
TK_EGFR_EGFR_Y	Q13480	GAB1	P00533	EGFR	Y373	A378S	378	Missense	distal	5	no	9.862	9.848	EPSD;PhosphoSitePlus	COSMIC	6.466	Down-regulation
TK_EGFR_EGFR_Y	Q13480	GAB1	P00533	EGFR	Y373	A366V	366	Missense	distal	-7	no	9.862	8.741	EPSD;PhosphoSitePlus	COSMIC	6.466	Down-regulation
TK_EGFR_EGFR_Y	Q13480	GAB1	P00533	EGFR	Y406	P413L	413	Missense	distal	7	no	12.131	11.840	PhosphoSitePlus;EPSD	COSMIC	6.466	Down-regulation
TK_EGFR_EGFR_Y	Q13480	GAB1	P00533	EGFR	Y447	P449H	449	Missense	proximal	2	no	12.802	12.540	EPSD;PhosphoSitePlus	COSMIC	6.466	Down-regulation
TK_EGFR_EGFR_Y	Q13480	GAB1	P00533	EGFR	Y447	E441Q	441	Missense	distal	-6	no	12.802	12.731	EPSD;PhosphoSitePlus	COSMIC	6.466	Down-regulation
TK_EGFR_EGFR_Y	Q13480	GAB1	P00533	EGFR	Y589	L596M	596	Missense	distal	7	no	15.609	15.826	EPSD;PhosphoSitePlus	COSMIC	6.466	Up-regulation
TK_EGFR_EGFR_Y	Q13480	GAB1	P00533	EGFR	Y589	N595D	595	Missense	distal	6	no	15.609	14.862	EPSD;PhosphoSitePlus	COSMIC	6.466	Down-regulation
TK_EGFR_EGFR_Y	Q13480	GAB1	P00533	EGFR	Y589	P591H	591	Missense	proximal	2	no	15.609	15.347	EPSD;PhosphoSitePlus	COSMIC	6.466	Down-regulation
TK_EGFR_EGFR_Y	Q13480	GAB1	P00533	EGFR	Y589	N593S	593	Missense	distal	4	no	15.609	15.872	EPSD;PhosphoSitePlus	COSMIC	6.466	Up-regulation
TK_EGFR_EGFR_Y	Q13480	GAB1	P00533	EGFR	Y589	S585R	585	Missense	distal	-4	no	15.609	15.556	EPSD;PhosphoSitePlus	COSMIC	6.466	Down-regulation
TK_EGFR_EGFR_Y	Q13480	GAB1	P00533	EGFR	Y589	N588K	588	Missense	proximal	-1	no	15.609	13.509	EPSD;PhosphoSitePlus	COSMIC	6.466	Down-regulation
TK_EGFR_EGFR_Y	Q13480	GAB1	P00533	EGFR	Y627	D631F	631	Missense	distal	4	no	10.746	11.233	EPSD;PhosphoSitePlus	COSMIC	6.466	Up-regulation
TK_EGFR_EGFR_Y	Q13480	GAB1	P00533	EGFR	Y627	D631Y	631	Missense	distal	4	no	10.746	11.414	EPSD;PhosphoSitePlus	COSMIC	6.466	Up-regulation
TK_EGFR_EGFR_Y	Q13480	GAB1	P00533	EGFR	Y627	D631V	631	Missense	distal	4	no	10.746	10.862	EPSD;PhosphoSitePlus	COSMIC	6.466	Up-regulation
TK_EGFR_EGFR_Y	Q13480	GAB1	P00533	EGFR	Y627	Q624L	624	Missense	distal	-3	no	10.746	8.076	EPSD;PhosphoSitePlus	COSMIC	6.466	Down-regulation
TK_EGFR_EGFR_Y	Q13480	GAB1	P00533	EGFR	Y627	L632I	632	Missense	distal	5	no	10.746	10.856	EPSD;PhosphoSitePlus	COSMIC	6.466	Up-regulation
TK_EGFR_EGFR_Y	Q13480	GAB1	P00533	EGFR	Y627	D631N	631	Missense	distal	4	no	10.746	10.224	EPSD;PhosphoSitePlus	COSMIC	6.466	Down-regulation
TK_EGFR_EGFR_Y	Q14457	BECN1	P00533	EGFR	Y233	Q240H	240	Missense	distal	7	no	7.122	6.837	PhosphoSitePlus;EPSD	COSMIC	6.466	Down-regulation
TK_EGFR_EGFR_Y	O14939	PLD2	P00533	EGFR	Y169	R172H	172	Missense	distal	3	no	8.543	8.669	EPSD	COSMIC	6.466	Up-regulation
TK_EGFR_EGFR_Y	P40818	USP8	P00533	EGFR	Y717	S718P	718	Missense	proximal	1	no	9.285	10.140	PhosphoSitePlus;EPSD	COSMIC	6.466	Up-regulation
TK_EGFR_EGFR_Y	P40818	USP8	P00533	EGFR	Y717	S718C	718	Missense	proximal	1	no	9.285	10.552	PhosphoSitePlus;EPSD	COSMIC	6.466	Up-regulation
TK_EGFR_EGFR_Y	P40818	USP8	P00533	EGFR	Y717	S718F	718	Missense	proximal	1	no	9.285	10.706	PhosphoSitePlus;EPSD	COSMIC	6.466	Up-regulation
TK_EGFR_EGFR_Y	P40818	USP8	P00533	EGFR	Y717	S719P	719	Missense	proximal	2	no	9.285	9.306	PhosphoSitePlus;EPSD	COSMIC	6.466	Up-regulation
TK_EGFR_EGFR_Y	P40818	USP8	P00533	EGFR	Y717	D721N	721	Missense	distal	4	no	9.285	8.763	PhosphoSitePlus;EPSD	COSMIC	6.466	Down-regulation
TK_EGFR_EGFR_Y	P40818	USP8	P00533	EGFR	Y717	R715H	715	Missense	proximal	-2	no	9.285	9.428	PhosphoSitePlus;EPSD	COSMIC	6.466	Up-regulation
TK_EGFR_EGFR_Y	P40818	USP8	P00533	EGFR	Y717	Y717S	717	Missense	central	0	yes	9.285	0.000	PhosphoSitePlus;EPSD	COSMIC	6.466	Loss
TK_EGFR_EGFR_Y	P40818	USP8	P00533	EGFR	Y717	S716Y	716	Missense	proximal	-1	no	9.285	7.959	PhosphoSitePlus;EPSD	COSMIC	6.466	Down-regulation
TK_EGFR_EGFR_Y	P40818	USP8	P00533	EGFR	Y717	P720L	720	Missense	distal	3	no	9.285	9.907	PhosphoSitePlus;EPSD	COSMIC	6.466	Up-regulation
TK_EGFR_EGFR_Y	P40818	USP8	P00533	EGFR	Y717	Y717C	717	Missense	central	0	yes	9.285	0.000	PhosphoSitePlus;EPSD	COSMIC	6.466	Loss
TK_EGFR_EGFR_Y	P40818	USP8	P00533	EGFR	Y717	L713R	713	Missense	distal	-4	no	9.285	10.393	PhosphoSitePlus;EPSD	COSMIC	6.466	Up-regulation
TK_EGFR_EGFR_Y	O00767	SCD	P00533	EGFR	Y55	P57S	57	Missense	proximal	2	no	15.341	15.320	EPSD;PhosphoSitePlus	COSMIC	6.466	Down-regulation
TK_EGFR_EGFR_Y	O00767	SCD	P00533	EGFR	Y59	P57S	57	Missense	proximal	-2	no	8.552	8.814	EPSD	COSMIC	6.466	Up-regulation
TK_EGFR_EGFR_Y	O00767	SCD	P00533	EGFR	Y59	G64S	64	Missense	distal	5	no	8.552	8.623	EPSD	COSMIC	6.466	Up-regulation
TK_EGFR_EGFR_Y	O00767	SCD	P00533	EGFR	Y71	W73R	73	Missense	proximal	2	no	4.638	7.399	EPSD	COSMIC	6.466	Gain
TK_EGFR_EGFR_Y	P04083	ANXA1	P00533	EGFR	Y39	V36E	36	Missense	distal	-3	no	5.723	10.300	EPSD	COSMIC;CCLE	6.466	Gain
TK_EGFR_EGFR_Y	P11171	EPB41	P00533	EGFR	Y660	D655G	655	Missense	distal	-5	no	11.750	10.820	EPSD	COSMIC	6.466	Down-regulation
TK_EGFR_EGFR_Y	P11171	EPB41	P00533	EGFR	Y660	M667L	667	Missense	distal	7	no	11.750	11.532	EPSD	COSMIC	6.466	Down-regulation
TK_EGFR_EGFR_Y	P11171	EPB41	P00533	EGFR	Y660	G656D	656	Missense	distal	-4	no	11.750	11.427	EPSD	COSMIC	6.466	Down-regulation
TK_EGFR_EGFR_Y	P11171	EPB41	P00533	EGFR	Y660	G656S	656	Missense	distal	-4	no	11.750	10.110	EPSD	COSMIC	6.466	Down-regulation
TK_EGFR_EGFR_Y	P11171	EPB41	P00533	EGFR	Y660	I661T	661	Missense	proximal	1	no	11.750	12.363	EPSD	COSMIC	6.466	Up-regulation
TK_EGFR_EGFR_Y	P11171	EPB41	P00533	EGFR	Y660	R653S	653	Missense	distal	-7	no	11.750	11.424	EPSD	COSMIC	6.466	Down-regulation
TK_EGFR_EGFR_Y	Q9UBN7	HDAC6	P00533	EGFR	Y570	S568Y	568	Missense	proximal	-2	no	9.897	6.607	PhosphoSitePlus	COSMIC	6.466	Down-regulation
TK_EGFR_EGFR_Y	Q9UBN7	HDAC6	P00533	EGFR	Y570	P573F	573	Missense	distal	3	no	9.897	9.898	PhosphoSitePlus	COSMIC	6.466	Up-regulation
TK_EGFR_EGFR_Y	Q9UBN7	HDAC6	P00533	EGFR	Y570	P573H	573	Missense	distal	3	no	9.897	9.744	PhosphoSitePlus	COSMIC	6.466	Down-regulation
TK_EGFR_EGFR_Y	Q9UBN7	HDAC6	P00533	EGFR	Y570	C572F	572	Missense	proximal	2	no	9.897	10.253	PhosphoSitePlus	COSMIC	6.466	Up-regulation
TK_EGFR_EGFR_Y	Q9UBN7	HDAC6	P00533	EGFR	Y570	D567Y	567	Missense	distal	-3	no	9.897	7.884	PhosphoSitePlus	COSMIC	6.466	Down-regulation
TK_EGFR_EGFR_Y	Q38SD2	LRRK1	P00533	EGFR	Y971	A976T	976	Missense	distal	5	no	11.746	11.635	PhosphoSitePlus	COSMIC	6.466	Down-regulation
TK_EGFR_EGFR_Y	Q38SD2	LRRK1	P00533	EGFR	Y971	Q973K	973	Missense	proximal	2	no	11.746	10.852	PhosphoSitePlus	COSMIC	6.466	Down-regulation
TK_EGFR_EGFR_Y	Q13315	ATM	P00533	EGFR	Y370	T372A	372	Missense	proximal	2	no	7.915	8.347	PhosphoSitePlus	COSMIC	6.466	Up-regulation
TK_EGFR_EGFR_Y	Q13315	ATM	P00533	EGFR	Y380	Y380N	380	Missense	central	0	yes	6.903	0.000	EPSD	COSMIC	6.466	Loss
TK_EGFR_EGFR_Y	Q13315	ATM	P00533	EGFR	Y380	P383A	383	Missense	distal	3	no	6.903	7.297	EPSD	COSMIC;GDSC;CCLE	6.466	Up-regulation
TK_EGFR_EGFR_Y	Q13315	ATM	P00533	EGFR	Y2404	I2401V	2401	Missense	distal	-3	no	5.649	6.604	EPSD	COSMIC	6.466	Gain
TK_EGFR_EGFR_Y	Q13315	ATM	P00533	EGFR	Y2969	L2965F	2965	Missense	distal	-4	no	9.042	10.912	EPSD	COSMIC;GDSC;CCLE	6.466	Up-regulation
TK_EGFR_EGFR_Y	Q13315	ATM	P00533	EGFR	Y2969	P2974L	2974	Missense	distal	5	no	9.042	9.001	EPSD	COSMIC;GDSC	6.466	Down-regulation
TK_EGFR_EGFR_Y	Q13315	ATM	P00533	EGFR	Y2969	D2976N	2976	Missense	distal	7	no	9.042	9.327	EPSD	COSMIC	6.466	Up-regulation
TK_EGFR_EGFR_Y	Q13315	ATM	P00533	EGFR	Y2969	P2974S	2974	Missense	distal	5	no	9.042	9.269	EPSD	COSMIC	6.466	Up-regulation
TK_EGFR_EGFR_Y	Q9P0J1	PDP1	P00533	EGFR	Y381	N377S	377	Missense	distal	-4	no	10.792	8.383	PhosphoSitePlus	COSMIC;GDSC;CCLE	6.466	Down-regulation
TK_EGFR_EGFR_Y	O15455	TLR3	P00533	EGFR	Y858	N861S	861	Missense	distal	3	no	9.583	9.487	PhosphoSitePlus	COSMIC	6.466	Down-regulation
TK_EGFR_EGFR_Y	O15455	TLR3	P00533	EGFR	Y858	D857A	857	Missense	proximal	-1	no	9.583	8.295	PhosphoSitePlus	COSMIC	6.466	Down-regulation
TK_EGFR_EGFR_Y	O95477	ABCA1	P00533	EGFR	Y325	I319V	319	Missense	distal	-6	no	9.459	9.468	EPSD	COSMIC;CCLE	6.466	Up-regulation
TK_EGFR_EGFR_Y	O15492	RGS16	P00533	EGFR	Y168	T161I	161	Missense	distal	-7	no	10.754	10.043	PhosphoSitePlus	COSMIC	6.466	Down-regulation
TK_EGFR_EGFR_Y	Q9P219	CCDC88C	P00533	EGFR	Y219	D218G	218	Missense	proximal	-1	no	11.339	10.182	EPSD	COSMIC	6.466	Down-regulation
TK_EGFR_EGFR_Y	P18031	PTPN1	P00533	EGFR	Y46	F52L	52	Missense	distal	6	no	7.735	7.232	EPSD	COSMIC	6.466	Down-regulation
TK_EGFR_EGFR_Y	P18031	PTPN1	P00533	EGFR	Y66	A69V	69	Missense	distal	3	no	12.851	12.992	PhosphoSitePlus	COSMIC	6.466	Up-regulation
TK_EGFR_EGFR_Y	P18031	PTPN1	P00533	EGFR	Y66	L71M	71	Missense	distal	5	no	12.851	13.113	PhosphoSitePlus	COSMIC	6.466	Up-regulation
TK_EGFR_EGFR_Y	P18031	PTPN1	P00533	EGFR	Y66	N64I	64	Missense	proximal	-2	no	12.851	9.474	PhosphoSitePlus	COSMIC	6.466	Down-regulation
TK_EGFR_EGFR_Y	P18031	PTPN1	P00533	EGFR	Y66	I72T	72	Missense	distal	6	no	12.851	12.558	PhosphoSitePlus	COSMIC	6.466	Down-regulation
TK_EGFR_EGFR_Y	P15311	EZR	P00533	EGFR	Y116	P119S	119	Missense	distal	3	no	10.057	10.425	EPSD	COSMIC	6.466	Up-regulation
TK_EGFR_EGFR_Y	P15311	EZR	P00533	EGFR	Y205	E199K	199	Missense	distal	-6	no	7.639	7.605	EPSD	COSMIC	6.466	Down-regulation
TK_EGFR_EGFR_Y	P15311	EZR	P00533	EGFR	Y354	R350Q	350	Missense	distal	-4	no	8.003	9.232	PhosphoSitePlus;EPSD	COSMIC	6.466	Up-regulation
TK_EGFR_EGFR_Y	P15311	EZR	P00533	EGFR	Y354	R350W	350	Missense	distal	-4	no	8.003	6.576	PhosphoSitePlus;EPSD	COSMIC	6.466	Down-regulation
TK_EGFR_EGFR_Y	P15311	EZR	P00533	EGFR	Y499	S505N	505	Missense	distal	6	no	12.598	13.209	EPSD	COSMIC	6.466	Up-regulation
TK_EGFR_EGFR_Y	P15311	EZR	P00533	EGFR	Y499	A494P	494	Missense	distal	-5	no	12.598	11.706	EPSD	COSMIC	6.466	Down-regulation
TK_EGFR_EGFR_Y	P15311	EZR	P00533	EGFR	Y499	T497M	497	Missense	proximal	-2	no	12.598	10.201	EPSD	COSMIC;GDSC	6.466	Down-regulation
TK_EGFR_EGFR_Y	P15311	EZR	P00533	EGFR	Y499	E492D	492	Missense	distal	-7	no	12.598	12.370	EPSD	COSMIC	6.466	Down-regulation
TK_EGFR_EGFR_Y	Q92529	SHC3	P00533	EGFR	Y406	S402P	402	Missense	distal	-4	no	12.044	11.386	EPSD	COSMIC	6.466	Down-regulation
TK_EGFR_EGFR_Y	Q92529	SHC3	P00533	EGFR	Y424	P422T	422	Missense	proximal	-2	no	11.166	9.296	EPSD	COSMIC;GDSC;CCLE	6.466	Down-regulation
TK_EGFR_EGFR_Y	P07948	LYN	P00533	EGFR	Y32	R34M	34	Missense	proximal	2	no	9.229	9.506	PhosphoSitePlus	COSMIC	6.466	Up-regulation
TK_EGFR_EGFR_Y	P07948	LYN	P00533	EGFR	Y117	S115R	115	Missense	proximal	-2	no	7.078	4.446	EPSD	COSMIC	6.466	Loss
TK_EGFR_EGFR_Y	P07948	LYN	P00533	EGFR	Y117	V118M	118	Missense	proximal	1	no	7.078	5.854	EPSD	COSMIC;CCLE	6.466	Loss
TK_EGFR_EGFR_Y	P07948	LYN	P00533	EGFR	Y316	E320Q	320	Missense	distal	4	no	7.732	7.978	EPSD	COSMIC	6.466	Up-regulation
TK_EGFR_EGFR_Y	P48050	KCNJ4	P00533	EGFR	Y234	L237M	237	Missense	distal	3	no	8.609	7.979	PhosphoSitePlus	COSMIC	6.466	Down-regulation
TK_EGFR_EGFR_Y	P48050	KCNJ4	P00533	EGFR	Y234	E233K	233	Missense	proximal	-1	no	8.609	6.209	PhosphoSitePlus	COSMIC	6.466	Loss
TK_EGFR_EGFR_Y	P14618	PKM	P00533	EGFR	Y175	V176M	176	Missense	proximal	1	no	7.028	5.805	EPSD	COSMIC	6.466	Loss
TK_EGFR_EGFR_Y	P14618	PKM	P00533	EGFR	Y175	V170M	170	Missense	distal	-5	no	7.028	7.179	EPSD	COSMIC	6.466	Up-regulation
TK_EGFR_EGFR_Y	P14618	PKM	P00533	EGFR	Y390	E396K	396	Missense	distal	6	no	7.756	7.797	EPSD	COSMIC;GDSC;CCLE	6.466	Up-regulation
TK_EGFR_EGFR_Y	P14618	PKM	P00533	EGFR	Y390	E397V	397	Missense	distal	7	no	7.756	7.645	EPSD	COSMIC	6.466	Down-regulation
TK_EGFR_EGFR_Y	P14618	PKM	P00533	EGFR	Y390	R383H	383	Missense	distal	-7	no	7.756	7.374	EPSD	COSMIC;CCLE	6.466	Down-regulation
TK_EGFR_EGFR_Y	Q8TDY4	ASAP3	P00533	EGFR	Y76	A79V	79	Missense	distal	3	no	10.997	11.138	EPSD	COSMIC	6.466	Up-regulation
TK_EGFR_EGFR_Y	Q8TDY4	ASAP3	P00533	EGFR	Y535	A541E	541	Missense	distal	6	no	6.799	7.105	EPSD	COSMIC	6.466	Up-regulation
TK_EGFR_EGFR_Y	Q8TDY4	ASAP3	P00533	EGFR	Y843	G836W	836	Missense	distal	-7	no	10.611	9.626	EPSD	COSMIC	6.466	Down-regulation
TK_EGFR_EGFR_Y	Q8TDY4	ASAP3	P00533	EGFR	Y843	G836V	836	Missense	distal	-7	no	10.611	9.872	EPSD	COSMIC	6.466	Down-regulation
TK_EGFR_EGFR_Y	Q8TDY4	ASAP3	P00533	EGFR	Y843	P845L	845	Missense	proximal	2	no	10.611	7.746	EPSD	COSMIC	6.466	Down-regulation
TK_EGFR_EGFR_Y	Q14164	IKBKE	P00533	EGFR	Y153	E147G	147	Missense	distal	-6	no	13.253	13.147	EPSD;PhosphoSitePlus	COSMIC	6.466	Down-regulation
TK_EGFR_EGFR_Y	Q14164	IKBKE	P00533	EGFR	Y153	K154R	154	Missense	proximal	1	no	13.253	12.431	EPSD;PhosphoSitePlus	COSMIC	6.466	Down-regulation
TK_EGFR_EGFR_Y	Q14164	IKBKE	P00533	EGFR	Y153	G159A	159	Missense	distal	6	no	13.253	13.141	EPSD;PhosphoSitePlus	COSMIC	6.466	Down-regulation
TK_EGFR_EGFR_Y	Q14164	IKBKE	P00533	EGFR	Y153	Y153C	153	Missense	central	0	yes	13.253	0.000	EPSD;PhosphoSitePlus	COSMIC	6.466	Loss
TK_EGFR_EGFR_Y	Q14164	IKBKE	P00533	EGFR	Y153	A160T	160	Missense	distal	7	no	13.253	13.166	EPSD;PhosphoSitePlus	COSMIC	6.466	Down-regulation
TK_EGFR_EGFR_Y	Q14164	IKBKE	P00533	EGFR	Y153	G159S	159	Missense	distal	6	no	13.253	13.005	EPSD;PhosphoSitePlus	COSMIC	6.466	Down-regulation
TK_EGFR_EGFR_Y	Q14164	IKBKE	P00533	EGFR	Y153	I152N	152	Missense	proximal	-1	no	13.253	14.052	EPSD;PhosphoSitePlus	COSMIC	6.466	Up-regulation
TK_EGFR_EGFR_Y	Q14164	IKBKE	P00533	EGFR	Y179	G175R	175	Missense	distal	-4	no	10.842	9.150	PhosphoSitePlus;EPSD	COSMIC	6.466	Down-regulation
TK_EGFR_EGFR_Y	Q14164	IKBKE	P00533	EGFR	Y179	Y179F	179	Missense	central	0	yes	10.842	0.000	PhosphoSitePlus;EPSD	COSMIC	6.466	Loss
TK_EGFR_EGFR_Y	Q14164	IKBKE	P00533	EGFR	Y179	E177Q	177	Missense	proximal	-2	no	10.842	8.831	PhosphoSitePlus;EPSD	COSMIC	6.466	Down-regulation
TK_EGFR_EGFR_Y	Q3V6T2	CCDC88A	P00533	EGFR	Y758	G760C	760	Missense	proximal	2	no	8.329	6.848	EPSD	COSMIC	6.466	Down-regulation
TK_EGFR_EGFR_Y	Q3V6T2	CCDC88A	P00533	EGFR	Y758	R753H	753	Missense	distal	-5	no	8.329	8.670	EPSD	COSMIC;GDSC;CCLE	6.466	Up-regulation
TK_EGFR_EGFR_Y	Q3V6T2	CCDC88A	P00533	EGFR	Y1384	K1382T	1382	Missense	proximal	-2	no	6.874	6.841	EPSD	COSMIC	6.466	Down-regulation
TK_EGFR_EGFR_Y	Q3V6T2	CCDC88A	P00533	EGFR	Y1384	S1387C	1387	Missense	distal	3	no	6.874	6.761	EPSD	COSMIC	6.466	Down-regulation
TK_EGFR_EGFR_Y	Q3V6T2	CCDC88A	P00533	EGFR	Y1384	F1383C	1383	Missense	proximal	-1	no	6.874	6.304	EPSD	COSMIC	6.466	Loss
TK_EGFR_EGFR_Y	Q3V6T2	CCDC88A	P00533	EGFR	Y1384	F1383V	1383	Missense	proximal	-1	no	6.874	5.582	EPSD	COSMIC	6.466	Loss
TK_EGFR_EGFR_Y	Q3V6T2	CCDC88A	P00533	EGFR	Y1384	P1388L	1388	Missense	distal	4	no	6.874	7.018	EPSD	COSMIC	6.466	Up-regulation
TK_EGFR_EGFR_Y	Q3V6T2	CCDC88A	P00533	EGFR	Y1765	S1768C	1768	Missense	distal	3	no	9.180	9.066	PhosphoSitePlus;EPSD	COSMIC	6.466	Down-regulation
TK_EGFR_EGFR_Y	Q3V6T2	CCDC88A	P00533	EGFR	Y1765	S1769Y	1769	Missense	distal	4	no	9.180	10.106	PhosphoSitePlus;EPSD	COSMIC	6.466	Up-regulation
TK_EGFR_EGFR_Y	Q3V6T2	CCDC88A	P00533	EGFR	Y1765	K1760N	1760	Missense	distal	-5	no	9.180	9.464	PhosphoSitePlus;EPSD	COSMIC	6.466	Up-regulation
TK_EGFR_EGFR_Y	Q3V6T2	CCDC88A	P00533	EGFR	Y1765	A1770T	1770	Missense	distal	5	no	9.180	9.069	PhosphoSitePlus;EPSD	COSMIC	6.466	Down-regulation
TK_EGFR_EGFR_Y	Q3V6T2	CCDC88A	P00533	EGFR	Y1765	P1758L	1758	Missense	distal	-7	no	9.180	9.100	PhosphoSitePlus;EPSD	COSMIC	6.466	Down-regulation
TK_EGFR_EGFR_Y	Q3V6T2	CCDC88A	P00533	EGFR	Y1765	A1770V	1770	Missense	distal	5	no	9.180	9.005	PhosphoSitePlus;EPSD	COSMIC	6.466	Down-regulation
TK_EGFR_EGFR_Y	Q3V6T2	CCDC88A	P00533	EGFR	Y1799	P1803S	1803	Missense	distal	4	no	8.742	8.180	EPSD;PhosphoSitePlus	COSMIC	6.466	Down-regulation
TK_EGFR_EGFR_Y	Q3V6T2	CCDC88A	P00533	EGFR	Y1799	S1796C	1796	Missense	distal	-3	no	8.742	7.553	EPSD;PhosphoSitePlus	COSMIC	6.466	Down-regulation
TK_EGFR_EGFR_Y	Q3V6T2	CCDC88A	P00533	EGFR	Y1799	A1800E	1800	Missense	proximal	1	no	8.742	8.155	EPSD;PhosphoSitePlus	COSMIC	6.466	Down-regulation
TK_EGFR_EGFR_Y	Q3V6T2	CCDC88A	P00533	EGFR	Y1799	R1804C	1804	Missense	distal	5	no	8.742	8.844	EPSD;PhosphoSitePlus	COSMIC	6.466	Up-regulation
TK_EGFR_EGFR_Y	Q3V6T2	CCDC88A	P00533	EGFR	Y1799	P1798L	1798	Missense	proximal	-1	no	8.742	8.016	EPSD;PhosphoSitePlus	COSMIC	6.466	Down-regulation
TK_EGFR_EGFR_Y	Q92952	KCNN1	P00533	EGFR	Y109	S107I	107	Missense	proximal	-2	no	7.204	4.692	PhosphoSitePlus	COSMIC	6.466	Loss
TK_EGFR_EGFR_Y	Q92952	KCNN1	P00533	EGFR	Y109	R105H	105	Missense	distal	-4	no	7.204	7.100	PhosphoSitePlus	COSMIC	6.466	Down-regulation
TK_EGFR_EGFR_Y	P37231	PPARG	P00533	EGFR	Y102	L97R	97	Missense	distal	-5	no	7.404	7.686	EPSD	COSMIC	6.466	Up-regulation
TK_EGFR_EGFR_Y	P37231	PPARG	P00533	EGFR	Y102	V108A	108	Missense	distal	6	no	7.404	7.821	EPSD	COSMIC	6.466	Up-regulation
TK_EGFR_EGFR_Y	Q9UKV8	AGO2	P00533	EGFR	Y393	Y393H	393	Missense	central	0	yes	8.879	0.000	PhosphoSitePlus	COSMIC	6.466	Loss
TK_EGFR_EGFR_Y	Q9UKV8	AGO2	P00533	EGFR	Y749	H742P	742	Missense	distal	-7	no	9.529	9.340	EPSD	COSMIC	6.466	Down-regulation
STE_STE20_PAKA_PAK2_ST	Q53QZ3	ARHGAP15	Q13177	PAK2	S233	R231S	231	Missense	proximal	-2	no	18.208	-5.516	EPSD	COSMIC	14.606	Loss
STE_STE20_PAKA_PAK2_ST	Q53QZ3	ARHGAP15	Q13177	PAK2	S233	R231G	231	Missense	proximal	-2	no	18.208	-1.120	EPSD	COSMIC	14.606	Loss
STE_STE20_PAKA_PAK2_ST	Q53QZ3	ARHGAP15	Q13177	PAK2	S233	F236V	236	Missense	distal	3	no	18.208	18.747	EPSD	COSMIC	14.606	Up-regulation
STE_STE20_PAKA_PAK2_ST	Q53QZ3	ARHGAP15	Q13177	PAK2	S233	H230N	230	Missense	distal	-3	no	18.208	18.660	EPSD	COSMIC;GDSC;CCLE	14.606	Up-regulation
STE_STE20_PAKA_PAK2_ST	Q53QZ3	ARHGAP15	Q13177	PAK2	S241	S243F	243	Missense	proximal	2	no	19.522	23.595	EPSD	COSMIC	14.606	Up-regulation
STE_STE20_PAKA_PAK2_ST	Q53QZ3	ARHGAP15	Q13177	PAK2	S241	F236V	236	Missense	distal	-5	no	19.522	18.237	EPSD	COSMIC	14.606	Down-regulation
STE_STE20_PAKA_PAK2_ST	Q53QZ3	ARHGAP15	Q13177	PAK2	S292	R289H	289	Missense	distal	-3	no	18.434	3.591	EPSD;PhosphoSitePlus	COSMIC	14.606	Loss
STE_STE20_PAKA_PAK2_ST	Q53QZ3	ARHGAP15	Q13177	PAK2	S292	C287W	287	Missense	distal	-5	no	18.434	17.520	EPSD;PhosphoSitePlus	COSMIC	14.606	Down-regulation
STE_STE20_PAKA_PAK2_ST	Q53QZ3	ARHGAP15	Q13177	PAK2	S292	S292F	292	Missense	central	0	yes	18.434	0.000	EPSD;PhosphoSitePlus	COSMIC	14.606	Loss
STE_STE20_PAKA_PAK2_ST	Q53QZ3	ARHGAP15	Q13177	PAK2	S292	E290K	290	Missense	proximal	-2	no	18.434	21.968	EPSD;PhosphoSitePlus	COSMIC	14.606	Up-regulation
STE_STE20_PAKA_PAK2_ST	Q53QZ3	ARHGAP15	Q13177	PAK2	S292	V294I	294	Missense	proximal	2	no	18.434	14.938	EPSD;PhosphoSitePlus	COSMIC	14.606	Down-regulation
STE_STE20_PAKA_PAK2_ST	Q53QZ3	ARHGAP15	Q13177	PAK2	S292	K299Q	299	Missense	distal	7	no	18.434	24.170	EPSD;PhosphoSitePlus	COSMIC	14.606	Up-regulation
STE_STE20_PAKA_PAK2_ST	Q53QZ3	ARHGAP15	Q13177	PAK2	T324	R317L	317	Missense	distal	-7	no	14.399	15.683	EPSD	COSMIC	14.606	Gain
STE_STE20_PAKA_PAK2_ST	Q53QZ3	ARHGAP15	Q13177	PAK2	T324	R329T	329	Missense	distal	5	no	14.399	14.972	EPSD	COSMIC;GDSC;CCLE	14.606	Gain
STE_STE20_PAKA_PAK2_ST	Q53QZ3	ARHGAP15	Q13177	PAK2	S343	H349Y	349	Missense	distal	6	no	24.999	25.589	EPSD	COSMIC;GDSC;CCLE	14.606	Up-regulation
STE_STE20_PAKA_PAK2_ST	Q53QZ3	ARHGAP15	Q13177	PAK2	S343	D341Y	341	Missense	proximal	-2	no	24.999	28.587	EPSD	COSMIC	14.606	Up-regulation
STE_STE20_PAKA_PAK2_ST	Q53QZ3	ARHGAP15	Q13177	PAK2	S343	H349Q	349	Missense	distal	6	no	24.999	25.537	EPSD	COSMIC	14.606	Up-regulation
STE_STE20_PAKA_PAK2_ST	Q53QZ3	ARHGAP15	Q13177	PAK2	S343	W345C	345	Missense	proximal	2	no	24.999	20.620	EPSD	COSMIC	14.606	Down-regulation
STE_STE20_PAKA_PAK2_ST	Q53QZ3	ARHGAP15	Q13177	PAK2	S343	H349D	349	Missense	distal	6	no	24.999	26.124	EPSD	COSMIC	14.606	Up-regulation
STE_STE20_PAKA_PAK2_ST	Q53QZ3	ARHGAP15	Q13177	PAK2	S393	K392N	392	Missense	proximal	-1	no	34.562	25.137	EPSD	COSMIC	14.606	Down-regulation
STE_STE20_PAKA_PAK2_ST	Q53QZ3	ARHGAP15	Q13177	PAK2	T405	N402K	402	Missense	distal	-3	no	9.825	23.936	EPSD	COSMIC	14.606	Gain
STE_STE20_PAKA_PAK2_ST	Q13177	PAK2	Q13177	PAK2	S19	I22M	22	Missense	distal	3	no	28.410	24.826	EPSD	COSMIC	14.606	Down-regulation
STE_STE20_PAKA_PAK2_ST	Q13177	PAK2	Q13177	PAK2	S19	P15H	15	Missense	distal	-4	no	28.410	26.335	EPSD	COSMIC	14.606	Down-regulation
STE_STE20_PAKA_PAK2_ST	Q13177	PAK2	Q13177	PAK2	S20	I22M	22	Missense	proximal	2	no	32.118	28.555	EPSD	COSMIC	14.606	Down-regulation
STE_STE20_PAKA_PAK2_ST	Q13177	PAK2	Q13177	PAK2	S20	P15H	15	Missense	distal	-5	no	32.118	29.488	EPSD	COSMIC	14.606	Down-regulation
STE_STE20_PAKA_PAK2_ST	Q13177	PAK2	Q13177	PAK2	S141	Y139N	139	Missense	proximal	-2	no	32.805	5.987	EPSD	COSMIC	14.606	Loss
STE_STE20_PAKA_PAK2_ST	Q13177	PAK2	Q13177	PAK2	S192	R196Q	196	Missense	distal	4	no	30.965	31.265	EPSD	COSMIC	14.606	Up-regulation
STE_STE20_PAKA_PAK2_ST	Q13177	PAK2	Q13177	PAK2	S197	R196Q	196	Missense	proximal	-1	no	23.729	16.555	EPSD	COSMIC	14.606	Down-regulation
STE_STE20_PAKA_PAK2_ST	Q13177	PAK2	Q13177	PAK2	S401	G405R	405	Missense	distal	4	no	14.649	11.182	EPSD	COSMIC	14.606	Loss
STE_STE20_PAKA_PAK2_ST	Q13177	PAK2	Q13177	PAK2	S401	P395H	395	Missense	distal	-6	no	14.649	17.515	EPSD	COSMIC	14.606	Up-regulation
STE_STE20_PAKA_PAK2_ST	Q13177	PAK2	Q13177	PAK2	T402	G405R	405	Missense	distal	3	no	35.000	33.642	PhosphoSitePlus	COSMIC	14.606	Down-regulation
STE_STE20_PAKA_PAK2_ST	Q13177	PAK2	Q13177	PAK2	T402	P395H	395	Missense	distal	-7	no	35.000	34.133	PhosphoSitePlus	COSMIC	14.606	Down-regulation
STE_STE20_PAKA_PAK2_ST	Q13177	PAK2	Q13177	PAK2	S490	E486V	486	Missense	distal	-4	no	22.155	23.576	EPSD	COSMIC	14.606	Up-regulation
STE_STE20_PAKA_PAK2_ST	P05412	JUN	Q13177	PAK2	T8	N15D	15	Missense	distal	7	no	19.613	21.921	PhosphoSitePlus;EPSD	COSMIC	14.606	Up-regulation
STE_STE20_PAKA_PAK2_ST	P05412	JUN	Q13177	PAK2	T8	T8I	8	Missense	central	0	yes	19.613	0.000	PhosphoSitePlus;EPSD	COSMIC	14.606	Loss
STE_STE20_PAKA_PAK2_ST	P05412	JUN	Q13177	PAK2	T8	D12H	12	Missense	distal	4	no	19.613	16.946	PhosphoSitePlus;EPSD	COSMIC	14.606	Down-regulation
STE_STE20_PAKA_PAK2_ST	P05412	JUN	Q13177	PAK2	S37	M38I	38	Missense	proximal	1	no	16.937	15.508	EPSD	COSMIC	14.606	Down-regulation
STE_STE20_PAKA_PAK2_ST	P05412	JUN	Q13177	PAK2	S37	K32E	32	Missense	distal	-5	no	16.937	15.559	EPSD	COSMIC	14.606	Down-regulation
STE_STE20_PAKA_PAK2_ST	P05412	JUN	Q13177	PAK2	S37	P31L	31	Missense	distal	-6	no	16.937	16.580	EPSD	COSMIC	14.606	Down-regulation
STE_STE20_PAKA_PAK2_ST	P05412	JUN	Q13177	PAK2	S37	S37R	37	Missense	central	0	yes	16.937	0.000	EPSD	COSMIC	14.606	Loss
STE_STE20_PAKA_PAK2_ST	P05412	JUN	Q13177	PAK2	S37	Q36H	36	Missense	proximal	-1	no	16.937	18.750	EPSD	COSMIC	14.606	Up-regulation
STE_STE20_PAKA_PAK2_ST	P05412	JUN	Q13177	PAK2	S37	S37N	37	Missense	central	0	yes	16.937	0.000	EPSD	COSMIC	14.606	Loss
STE_STE20_PAKA_PAK2_ST	P05412	JUN	Q13177	PAK2	S48	L53F	53	Missense	distal	5	no	15.111	12.141	EPSD	COSMIC	14.606	Loss
STE_STE20_PAKA_PAK2_ST	P05412	JUN	Q13177	PAK2	S48	L49M	49	Missense	proximal	1	no	15.111	16.518	EPSD	COSMIC	14.606	Up-regulation
STE_STE20_PAKA_PAK2_ST	P05412	JUN	Q13177	PAK2	S48	P51T	51	Missense	distal	3	no	15.111	13.713	EPSD	COSMIC;CCLE	14.606	Loss
STE_STE20_PAKA_PAK2_ST	P05412	JUN	Q13177	PAK2	S58	L53F	53	Missense	distal	-5	no	14.800	16.894	EPSD	COSMIC	14.606	Up-regulation
STE_STE20_PAKA_PAK2_ST	P05412	JUN	Q13177	PAK2	S58	K56N	56	Missense	proximal	-2	no	14.800	-12.413	EPSD	COSMIC	14.606	Loss
STE_STE20_PAKA_PAK2_ST	P05412	JUN	Q13177	PAK2	S58	P51T	51	Missense	distal	-7	no	14.800	14.660	EPSD	COSMIC;CCLE	14.606	Down-regulation
STE_STE20_PAKA_PAK2_ST	P05412	JUN	Q13177	PAK2	S58	L61F	61	Missense	distal	3	no	14.800	15.933	EPSD	COSMIC	14.606	Up-regulation
STE_STE20_PAKA_PAK2_ST	P05412	JUN	Q13177	PAK2	S83	I81M	81	Missense	proximal	-2	no	9.510	15.274	EPSD	COSMIC	14.606	Gain
STE_STE20_PAKA_PAK2_ST	P05412	JUN	Q13177	PAK2	T89	P92Q	92	Missense	distal	3	no	33.388	30.562	EPSD;PhosphoSitePlus	COSMIC	14.606	Down-regulation
STE_STE20_PAKA_PAK2_ST	P05412	JUN	Q13177	PAK2	T89	P94S	94	Missense	distal	5	no	33.388	34.934	EPSD;PhosphoSitePlus	COSMIC	14.606	Up-regulation
STE_STE20_PAKA_PAK2_ST	P05412	JUN	Q13177	PAK2	T93	P100L	100	Missense	distal	7	no	24.978	27.404	EPSD;PhosphoSitePlus	COSMIC	14.606	Up-regulation
STE_STE20_PAKA_PAK2_ST	P05412	JUN	Q13177	PAK2	T93	P92Q	92	Missense	proximal	-1	no	24.978	24.518	EPSD;PhosphoSitePlus	COSMIC	14.606	Down-regulation
STE_STE20_PAKA_PAK2_ST	P05412	JUN	Q13177	PAK2	T93	L98M	98	Missense	distal	5	no	24.978	25.243	EPSD;PhosphoSitePlus	COSMIC	14.606	Up-regulation
STE_STE20_PAKA_PAK2_ST	P05412	JUN	Q13177	PAK2	T93	P94S	94	Missense	proximal	1	no	24.978	27.300	EPSD;PhosphoSitePlus	COSMIC	14.606	Up-regulation
STE_STE20_PAKA_PAK2_ST	P05412	JUN	Q13177	PAK2	S243	P240Q	240	Missense	distal	-3	no	17.257	9.718	EPSD	COSMIC	14.606	Loss
STE_STE20_PAKA_PAK2_ST	P05412	JUN	Q13177	PAK2	S243	T239I	239	Missense	distal	-4	no	17.257	17.645	EPSD	COSMIC	14.606	Up-regulation
STE_STE20_PAKA_PAK2_ST	P05412	JUN	Q13177	PAK2	T286	E293K	293	Missense	distal	7	no	28.963	26.258	EPSD;PhosphoSitePlus	COSMIC	14.606	Down-regulation
STE_STE20_PAKA_PAK2_ST	P05412	JUN	Q13177	PAK2	T286	L287S	287	Missense	proximal	1	no	28.963	29.943	EPSD;PhosphoSitePlus	COSMIC	14.606	Up-regulation
STE_STE20_PAKA_PAK2_ST	P05412	JUN	Q13177	PAK2	T286	E293Q	293	Missense	distal	7	no	28.963	31.994	EPSD;PhosphoSitePlus	COSMIC	14.606	Up-regulation
STE_STE20_PAKA_PAK2_ST	P01106	MYC	Q13177	PAK2	S62	P57S	57	Missense	distal	-5	no	23.852	22.941	EPSD	COSMIC;CCLE	14.606	Down-regulation
STE_STE20_PAKA_PAK2_ST	P01106	MYC	Q13177	PAK2	S62	S62P	62	Missense	central	0	yes	23.852	0.000	EPSD	COSMIC;CCLE	14.606	Loss
STE_STE20_PAKA_PAK2_ST	P01106	MYC	Q13177	PAK2	S62	P59L	59	Missense	distal	-3	no	23.852	24.198	EPSD	COSMIC;CCLE	14.606	Up-regulation
STE_STE20_PAKA_PAK2_ST	P01106	MYC	Q13177	PAK2	S62	T58N	58	Missense	distal	-4	no	23.852	25.361	EPSD	COSMIC;CCLE	14.606	Up-regulation
STE_STE20_PAKA_PAK2_ST	P01106	MYC	Q13177	PAK2	S62	P60H	60	Missense	proximal	-2	no	23.852	28.221	EPSD	COSMIC;CCLE	14.606	Up-regulation
STE_STE20_PAKA_PAK2_ST	P01106	MYC	Q13177	PAK2	S62	P63L	63	Missense	proximal	1	no	23.852	25.194	EPSD	COSMIC	14.606	Up-regulation
STE_STE20_PAKA_PAK2_ST	P01106	MYC	Q13177	PAK2	S62	P63H	63	Missense	proximal	1	no	23.852	25.030	EPSD	COSMIC	14.606	Up-regulation
STE_STE20_PAKA_PAK2_ST	P01106	MYC	Q13177	PAK2	S62	T58A	58	Missense	distal	-4	no	23.852	23.422	EPSD	COSMIC;CCLE	14.606	Down-regulation
STE_STE20_PAKA_PAK2_ST	P01106	MYC	Q13177	PAK2	S62	P59A	59	Missense	distal	-3	no	23.852	29.777	EPSD	COSMIC;CCLE	14.606	Up-regulation
STE_STE20_PAKA_PAK2_ST	P01106	MYC	Q13177	PAK2	S62	P59R	59	Missense	distal	-3	no	23.852	33.456	EPSD	COSMIC	14.606	Up-regulation
STE_STE20_PAKA_PAK2_ST	P01106	MYC	Q13177	PAK2	S62	P60A	60	Missense	proximal	-2	no	23.852	15.730	EPSD	COSMIC;CCLE	14.606	Down-regulation
STE_STE20_PAKA_PAK2_ST	P01106	MYC	Q13177	PAK2	S62	P57T	57	Missense	distal	-5	no	23.852	24.253	EPSD	COSMIC;CCLE	14.606	Up-regulation
STE_STE20_PAKA_PAK2_ST	P01106	MYC	Q13177	PAK2	S62	P59S	59	Missense	distal	-3	no	23.852	22.796	EPSD	COSMIC;CCLE	14.606	Down-regulation
STE_STE20_PAKA_PAK2_ST	P01106	MYC	Q13177	PAK2	S62	S62F	62	Missense	central	0	yes	23.852	0.000	EPSD	COSMIC	14.606	Loss
STE_STE20_PAKA_PAK2_ST	P01106	MYC	Q13177	PAK2	S62	T58I	58	Missense	distal	-4	no	23.852	24.240	EPSD	COSMIC;CCLE	14.606	Up-regulation
STE_STE20_PAKA_PAK2_ST	P01106	MYC	Q13177	PAK2	S62	T58P	58	Missense	distal	-4	no	23.852	24.788	EPSD	COSMIC	14.606	Up-regulation
STE_STE20_PAKA_PAK2_ST	P01106	MYC	Q13177	PAK2	S62	S64R	64	Missense	proximal	2	no	23.852	16.554	EPSD	COSMIC;CCLE	14.606	Down-regulation
STE_STE20_PAKA_PAK2_ST	P01106	MYC	Q13177	PAK2	S62	P57L	57	Missense	distal	-5	no	23.852	21.299	EPSD	COSMIC;CCLE	14.606	Down-regulation
STE_STE20_PAKA_PAK2_ST	P01106	MYC	Q13177	PAK2	S62	P63S	63	Missense	proximal	1	no	23.852	26.174	EPSD	COSMIC;CCLE	14.606	Up-regulation
STE_STE20_PAKA_PAK2_ST	P01106	MYC	Q13177	PAK2	S62	R66H	66	Missense	distal	4	no	23.852	23.283	EPSD	COSMIC	14.606	Down-regulation
STE_STE20_PAKA_PAK2_ST	P01106	MYC	Q13177	PAK2	S62	P57F	57	Missense	distal	-5	no	23.852	23.394	EPSD	COSMIC	14.606	Down-regulation
STE_STE20_PAKA_PAK2_ST	P01106	MYC	Q13177	PAK2	S62	P59Q	59	Missense	distal	-3	no	23.852	16.314	EPSD	COSMIC;CCLE	14.606	Down-regulation
STE_STE20_PAKA_PAK2_ST	P01106	MYC	Q13177	PAK2	S62	P59T	59	Missense	distal	-3	no	23.852	26.026	EPSD	COSMIC	14.606	Up-regulation
STE_STE20_PAKA_PAK2_ST	P01106	MYC	Q13177	PAK2	S62	P60S	60	Missense	proximal	-2	no	23.852	9.453	EPSD	COSMIC	14.606	Loss
STE_STE20_PAKA_PAK2_ST	P01106	MYC	Q13177	PAK2	S62	P63A	63	Missense	proximal	1	no	23.852	24.137	EPSD	COSMIC	14.606	Up-regulation
STE_STE20_PAKA_PAK2_ST	P01106	MYC	Q13177	PAK2	S62	S64N	64	Missense	proximal	2	no	23.852	21.442	EPSD	COSMIC	14.606	Down-regulation
STE_STE20_PAKA_PAK2_ST	P01106	MYC	Q13177	PAK2	S62	P60L	60	Missense	proximal	-2	no	23.852	14.309	EPSD	COSMIC	14.606	Loss
STE_STE20_PAKA_PAK2_ST	P01106	MYC	Q13177	PAK2	S62	P57A	57	Missense	distal	-5	no	23.852	21.525	EPSD	COSMIC	14.606	Down-regulation
STE_STE20_PAKA_PAK2_ST	P01106	MYC	Q13177	PAK2	S62	L56V	56	Missense	distal	-6	no	23.852	22.660	EPSD	COSMIC	14.606	Down-regulation
STE_STE20_PAKA_PAK2_ST	P01106	MYC	Q13177	PAK2	S62	P63R	63	Missense	proximal	1	no	23.852	21.792	EPSD	COSMIC	14.606	Down-regulation
STE_STE20_PAKA_PAK2_ST	P01106	MYC	Q13177	PAK2	S62	L56M	56	Missense	distal	-6	no	23.852	27.173	EPSD	COSMIC	14.606	Up-regulation
STE_STE20_PAKA_PAK2_ST	P01106	MYC	Q13177	PAK2	S62	L69V	69	Missense	distal	7	no	23.852	24.624	EPSD	COSMIC	14.606	Up-regulation
STE_STE20_PAKA_PAK2_ST	P01106	MYC	Q13177	PAK2	S62	P63T	63	Missense	proximal	1	no	23.852	24.476	EPSD	COSMIC	14.606	Up-regulation
STE_STE20_PAKA_PAK2_ST	P01106	MYC	Q13177	PAK2	S62	S67F	67	Missense	distal	5	no	23.852	22.363	EPSD	COSMIC	14.606	Down-regulation
STE_STE20_PAKA_PAK2_ST	P01106	MYC	Q13177	PAK2	S62	S62A	62	Missense	central	0	yes	23.852	0.000	EPSD	COSMIC	14.606	Loss
STE_STE20_PAKA_PAK2_ST	P01106	MYC	Q13177	PAK2	S62	P57R	57	Missense	distal	-5	no	23.852	20.872	EPSD	COSMIC	14.606	Down-regulation
STE_STE20_PAKA_PAK2_ST	P01106	MYC	Q13177	PAK2	S62	L69P	69	Missense	distal	7	no	23.852	21.427	EPSD	COSMIC	14.606	Down-regulation
STE_STE20_PAKA_PAK2_ST	P01106	MYC	Q13177	PAK2	S62	P60T	60	Missense	proximal	-2	no	23.852	25.442	EPSD	COSMIC;CCLE	14.606	Up-regulation
STE_STE20_PAKA_PAK2_ST	P01106	MYC	Q13177	PAK2	S62	L69F	69	Missense	distal	7	no	23.852	25.061	EPSD	COSMIC	14.606	Up-regulation
STE_STE20_PAKA_PAK2_ST	P01106	MYC	Q13177	PAK2	S62	S64T	64	Missense	proximal	2	no	23.852	20.954	EPSD	COSMIC	14.606	Down-regulation
STE_STE20_PAKA_PAK2_ST	P01106	MYC	Q13177	PAK2	S62	R65C	65	Missense	distal	3	no	23.852	22.783	EPSD	COSMIC	14.606	Down-regulation
STE_STE20_PAKA_PAK2_ST	P01106	MYC	Q13177	PAK2	S62	L55P	55	Missense	distal	-7	no	23.852	22.572	EPSD	COSMIC	14.606	Down-regulation
STE_STE20_PAKA_PAK2_ST	P01106	MYC	Q13177	PAK2	S62	L55M	55	Missense	distal	-7	no	23.852	22.258	EPSD	COSMIC	14.606	Down-regulation
STE_STE20_PAKA_PAK2_ST	P01106	MYC	Q13177	PAK2	S67	S62P	62	Missense	distal	-5	no	17.246	18.157	EPSD	COSMIC;CCLE	14.606	Up-regulation
STE_STE20_PAKA_PAK2_ST	P01106	MYC	Q13177	PAK2	S67	P60H	60	Missense	distal	-7	no	17.246	16.379	EPSD	COSMIC;CCLE	14.606	Down-regulation
STE_STE20_PAKA_PAK2_ST	P01106	MYC	Q13177	PAK2	S67	P63L	63	Missense	distal	-4	no	17.246	16.793	EPSD	COSMIC	14.606	Down-regulation
STE_STE20_PAKA_PAK2_ST	P01106	MYC	Q13177	PAK2	S67	P63H	63	Missense	distal	-4	no	17.246	15.171	EPSD	COSMIC	14.606	Down-regulation
STE_STE20_PAKA_PAK2_ST	P01106	MYC	Q13177	PAK2	S67	P60A	60	Missense	distal	-7	no	17.246	17.189	EPSD	COSMIC;CCLE	14.606	Down-regulation
STE_STE20_PAKA_PAK2_ST	P01106	MYC	Q13177	PAK2	S67	S62F	62	Missense	distal	-5	no	17.246	17.699	EPSD	COSMIC	14.606	Up-regulation
STE_STE20_PAKA_PAK2_ST	P01106	MYC	Q13177	PAK2	S67	C70R	70	Missense	distal	3	no	17.246	18.316	EPSD	COSMIC	14.606	Up-regulation
STE_STE20_PAKA_PAK2_ST	P01106	MYC	Q13177	PAK2	S67	S64R	64	Missense	distal	-3	no	17.246	27.906	EPSD	COSMIC;CCLE	14.606	Up-regulation
STE_STE20_PAKA_PAK2_ST	P01106	MYC	Q13177	PAK2	S67	P63S	63	Missense	distal	-4	no	17.246	16.619	EPSD	COSMIC;CCLE	14.606	Down-regulation
STE_STE20_PAKA_PAK2_ST	P01106	MYC	Q13177	PAK2	S67	R66H	66	Missense	proximal	-1	no	17.246	11.885	EPSD	COSMIC	14.606	Loss
STE_STE20_PAKA_PAK2_ST	P01106	MYC	Q13177	PAK2	S67	P60S	60	Missense	distal	-7	no	17.246	16.949	EPSD	COSMIC	14.606	Down-regulation
STE_STE20_PAKA_PAK2_ST	P01106	MYC	Q13177	PAK2	S67	S71L	71	Missense	distal	4	no	17.246	17.194	EPSD	COSMIC	14.606	Down-regulation
STE_STE20_PAKA_PAK2_ST	P01106	MYC	Q13177	PAK2	S67	P63A	63	Missense	distal	-4	no	17.246	15.880	EPSD	COSMIC	14.606	Down-regulation
STE_STE20_PAKA_PAK2_ST	P01106	MYC	Q13177	PAK2	S67	S64N	64	Missense	distal	-3	no	17.246	13.515	EPSD	COSMIC	14.606	Loss
STE_STE20_PAKA_PAK2_ST	P01106	MYC	Q13177	PAK2	S67	P60L	60	Missense	distal	-7	no	17.246	18.527	EPSD	COSMIC	14.606	Up-regulation
STE_STE20_PAKA_PAK2_ST	P01106	MYC	Q13177	PAK2	S67	Y74N	74	Missense	distal	7	no	17.246	18.552	EPSD	COSMIC;CCLE	14.606	Up-regulation
STE_STE20_PAKA_PAK2_ST	P01106	MYC	Q13177	PAK2	S67	P63R	63	Missense	distal	-4	no	17.246	16.018	EPSD	COSMIC	14.606	Down-regulation
STE_STE20_PAKA_PAK2_ST	P01106	MYC	Q13177	PAK2	S67	L69V	69	Missense	proximal	2	no	17.246	23.277	EPSD	COSMIC	14.606	Up-regulation
STE_STE20_PAKA_PAK2_ST	P01106	MYC	Q13177	PAK2	S67	P63T	63	Missense	distal	-4	no	17.246	16.310	EPSD	COSMIC	14.606	Down-regulation
STE_STE20_PAKA_PAK2_ST	P01106	MYC	Q13177	PAK2	S67	Y74H	74	Missense	distal	7	no	17.246	16.589	EPSD	COSMIC	14.606	Down-regulation
STE_STE20_PAKA_PAK2_ST	P01106	MYC	Q13177	PAK2	S67	S67F	67	Missense	central	0	yes	17.246	0.000	EPSD	COSMIC	14.606	Loss
STE_STE20_PAKA_PAK2_ST	P01106	MYC	Q13177	PAK2	S67	S62A	62	Missense	distal	-5	no	17.246	15.830	EPSD	COSMIC	14.606	Down-regulation
STE_STE20_PAKA_PAK2_ST	P01106	MYC	Q13177	PAK2	S67	L69P	69	Missense	proximal	2	no	17.246	14.038	EPSD	COSMIC	14.606	Loss
STE_STE20_PAKA_PAK2_ST	P01106	MYC	Q13177	PAK2	S67	C70W	70	Missense	distal	3	no	17.246	17.457	EPSD	COSMIC	14.606	Up-regulation
STE_STE20_PAKA_PAK2_ST	P01106	MYC	Q13177	PAK2	S67	P60T	60	Missense	distal	-7	no	17.246	17.107	EPSD	COSMIC;CCLE	14.606	Down-regulation
STE_STE20_PAKA_PAK2_ST	P01106	MYC	Q13177	PAK2	S67	S71W	71	Missense	distal	4	no	17.246	18.574	EPSD	COSMIC	14.606	Up-regulation
STE_STE20_PAKA_PAK2_ST	P01106	MYC	Q13177	PAK2	S67	L69F	69	Missense	proximal	2	no	17.246	25.022	EPSD	COSMIC	14.606	Up-regulation
STE_STE20_PAKA_PAK2_ST	P01106	MYC	Q13177	PAK2	S67	S73P	73	Missense	distal	6	no	17.246	18.274	EPSD	COSMIC	14.606	Up-regulation
STE_STE20_PAKA_PAK2_ST	P01106	MYC	Q13177	PAK2	S67	S64T	64	Missense	distal	-3	no	17.246	20.476	EPSD	COSMIC	14.606	Up-regulation
STE_STE20_PAKA_PAK2_ST	P01106	MYC	Q13177	PAK2	S67	R65C	65	Missense	proximal	-2	no	17.246	5.645	EPSD	COSMIC	14.606	Loss
STE_STE20_PAKA_PAK2_ST	P01106	MYC	Q13177	PAK2	S67	P72F	72	Missense	distal	5	no	17.246	17.303	EPSD	COSMIC	14.606	Up-regulation
STE_STE20_PAKA_PAK2_ST	P01106	MYC	Q13177	PAK2	S67	P72R	72	Missense	distal	5	no	17.246	17.746	EPSD	COSMIC	14.606	Up-regulation
STE_STE20_PAKA_PAK2_ST	P01106	MYC	Q13177	PAK2	S159	K157T	157	Missense	proximal	-2	no	13.916	14.834	EPSD	COSMIC	14.606	Gain
STE_STE20_PAKA_PAK2_ST	P01106	MYC	Q13177	PAK2	S159	A155S	155	Missense	distal	-4	no	13.916	14.655	EPSD	COSMIC	14.606	Gain
STE_STE20_PAKA_PAK2_ST	P01106	MYC	Q13177	PAK2	S159	Y152N	152	Missense	distal	-7	no	13.916	15.922	EPSD	COSMIC	14.606	Gain
STE_STE20_PAKA_PAK2_ST	P01106	MYC	Q13177	PAK2	S159	A154T	154	Missense	distal	-5	no	13.916	16.644	EPSD	COSMIC	14.606	Gain
STE_STE20_PAKA_PAK2_ST	P01106	MYC	Q13177	PAK2	S159	Q153H	153	Missense	distal	-6	no	13.916	16.786	EPSD	COSMIC	14.606	Gain
STE_STE20_PAKA_PAK2_ST	P01106	MYC	Q13177	PAK2	S159	A165D	165	Missense	distal	6	no	13.916	15.172	EPSD	COSMIC	14.606	Gain
STE_STE20_PAKA_PAK2_ST	P01106	MYC	Q13177	PAK2	S249	D251N	251	Missense	proximal	2	no	8.377	19.852	EPSD	COSMIC;CCLE	14.606	Gain
STE_STE20_PAKA_PAK2_ST	P01106	MYC	Q13177	PAK2	S249	P246R	246	Missense	distal	-3	no	8.377	17.981	EPSD	COSMIC	14.606	Gain
STE_STE20_PAKA_PAK2_ST	P01106	MYC	Q13177	PAK2	S250	P245S	245	Missense	distal	-5	no	17.884	16.973	EPSD	COSMIC	14.606	Down-regulation
STE_STE20_PAKA_PAK2_ST	P01106	MYC	Q13177	PAK2	S250	E257G	257	Missense	distal	7	no	17.884	20.657	EPSD	COSMIC	14.606	Up-regulation
STE_STE20_PAKA_PAK2_ST	P01106	MYC	Q13177	PAK2	S250	E253K	253	Missense	distal	3	no	17.884	16.484	EPSD	COSMIC	14.606	Down-regulation
STE_STE20_PAKA_PAK2_ST	P01106	MYC	Q13177	PAK2	S250	S249I	249	Missense	proximal	-1	no	17.884	19.311	EPSD	COSMIC	14.606	Up-regulation
STE_STE20_PAKA_PAK2_ST	P01106	MYC	Q13177	PAK2	S250	D251N	251	Missense	proximal	1	no	17.884	20.068	EPSD	COSMIC;CCLE	14.606	Up-regulation
STE_STE20_PAKA_PAK2_ST	P01106	MYC	Q13177	PAK2	S250	P245A	245	Missense	distal	-5	no	17.884	15.557	EPSD	COSMIC	14.606	Down-regulation
STE_STE20_PAKA_PAK2_ST	P01106	MYC	Q13177	PAK2	S250	S252F	252	Missense	proximal	2	no	17.884	21.957	EPSD	COSMIC	14.606	Up-regulation
STE_STE20_PAKA_PAK2_ST	P01106	MYC	Q13177	PAK2	S250	S249N	249	Missense	proximal	-1	no	17.884	13.716	EPSD	COSMIC;CCLE	14.606	Loss
STE_STE20_PAKA_PAK2_ST	P01106	MYC	Q13177	PAK2	S250	S249T	249	Missense	proximal	-1	no	17.884	16.912	EPSD	COSMIC	14.606	Down-regulation
STE_STE20_PAKA_PAK2_ST	P01106	MYC	Q13177	PAK2	S250	T244K	244	Missense	distal	-6	no	17.884	18.212	EPSD	COSMIC	14.606	Up-regulation
STE_STE20_PAKA_PAK2_ST	P01106	MYC	Q13177	PAK2	S250	P245Q	245	Missense	distal	-5	no	17.884	16.522	EPSD	COSMIC	14.606	Down-regulation
STE_STE20_PAKA_PAK2_ST	P01106	MYC	Q13177	PAK2	S250	P246S	246	Missense	distal	-4	no	17.884	17.257	EPSD	COSMIC	14.606	Down-regulation
STE_STE20_PAKA_PAK2_ST	P01106	MYC	Q13177	PAK2	S250	S250I	250	Missense	central	0	yes	17.884	0.000	EPSD	COSMIC	14.606	Loss
STE_STE20_PAKA_PAK2_ST	P01106	MYC	Q13177	PAK2	S250	S250C	250	Missense	central	0	yes	17.884	0.000	EPSD	COSMIC	14.606	Loss
STE_STE20_PAKA_PAK2_ST	P01106	MYC	Q13177	PAK2	S250	P246R	246	Missense	distal	-4	no	17.884	16.656	EPSD	COSMIC	14.606	Down-regulation
STE_STE20_PAKA_PAK2_ST	P01106	MYC	Q13177	PAK2	S250	E243G	243	Missense	distal	-7	no	17.884	18.700	EPSD	COSMIC	14.606	Up-regulation
STE_STE20_PAKA_PAK2_ST	P01106	MYC	Q13177	PAK2	S250	D251E	251	Missense	proximal	1	no	17.884	19.791	EPSD	COSMIC	14.606	Up-regulation
STE_STE20_PAKA_PAK2_ST	P01106	MYC	Q13177	PAK2	S250	P245L	245	Missense	distal	-5	no	17.884	15.331	EPSD	COSMIC	14.606	Down-regulation
STE_STE20_PAKA_PAK2_ST	P01106	MYC	Q13177	PAK2	S250	S250R	250	Missense	central	0	yes	17.884	0.000	EPSD	COSMIC	14.606	Loss
STE_STE20_PAKA_PAK2_ST	P01106	MYC	Q13177	PAK2	S250	S252Y	252	Missense	proximal	2	no	17.884	23.077	EPSD	COSMIC	14.606	Up-regulation
STE_STE20_PAKA_PAK2_ST	P01106	MYC	Q13177	PAK2	S250	E257Q	257	Missense	distal	7	no	17.884	20.915	EPSD	COSMIC	14.606	Up-regulation
STE_STE20_PAKA_PAK2_ST	P01106	MYC	Q13177	PAK2	S250	T247I	247	Missense	distal	-3	no	17.884	11.703	EPSD	COSMIC	14.606	Loss
STE_STE20_PAKA_PAK2_ST	P01106	MYC	Q13177	PAK2	S250	E243Q	243	Missense	distal	-7	no	17.884	17.791	EPSD	COSMIC	14.606	Down-regulation
STE_STE20_PAKA_PAK2_ST	P01106	MYC	Q13177	PAK2	S250	S249R	249	Missense	proximal	-1	no	17.884	18.738	EPSD	COSMIC;CCLE	14.606	Up-regulation
STE_STE20_PAKA_PAK2_ST	P01106	MYC	Q13177	PAK2	S250	E243V	243	Missense	distal	-7	no	17.884	19.333	EPSD	COSMIC	14.606	Up-regulation
STE_STE20_PAKA_PAK2_ST	P01106	MYC	Q13177	PAK2	S279	S283F	283	Missense	distal	4	no	19.143	21.302	EPSD	COSMIC	14.606	Up-regulation
STE_STE20_PAKA_PAK2_ST	P01106	MYC	Q13177	PAK2	S279	S277L	277	Missense	proximal	-2	no	19.143	23.999	EPSD	COSMIC	14.606	Up-regulation
STE_STE20_PAKA_PAK2_ST	P01106	MYC	Q13177	PAK2	S279	S279C	279	Missense	central	0	yes	19.143	0.000	EPSD	COSMIC	14.606	Loss
STE_STE20_PAKA_PAK2_ST	P01106	MYC	Q13177	PAK2	S279	S283Y	283	Missense	distal	4	no	19.143	19.303	EPSD	COSMIC	14.606	Up-regulation
STE_STE20_PAKA_PAK2_ST	P01106	MYC	Q13177	PAK2	S279	P273H	273	Missense	distal	-6	no	19.143	22.009	EPSD	COSMIC	14.606	Up-regulation
STE_STE20_PAKA_PAK2_ST	P01106	MYC	Q13177	PAK2	S279	P282A	282	Missense	distal	3	no	19.143	17.792	EPSD	COSMIC	14.606	Down-regulation
STE_STE20_PAKA_PAK2_ST	P01106	MYC	Q13177	PAK2	S279	G285E	285	Missense	distal	6	no	19.143	18.314	EPSD	COSMIC	14.606	Down-regulation
STE_STE20_PAKA_PAK2_ST	P01106	MYC	Q13177	PAK2	S279	G280R	280	Missense	proximal	1	no	19.143	18.723	EPSD	COSMIC	14.606	Down-regulation
STE_STE20_PAKA_PAK2_ST	P01106	MYC	Q13177	PAK2	S279	G274D	274	Missense	distal	-5	no	19.143	20.208	EPSD	COSMIC	14.606	Up-regulation
STE_STE20_PAKA_PAK2_ST	P01106	MYC	Q13177	PAK2	S279	A272P	272	Missense	distal	-7	no	19.143	19.199	EPSD	COSMIC	14.606	Up-regulation
STE_STE20_PAKA_PAK2_ST	P01106	MYC	Q13177	PAK2	S279	S281F	281	Missense	proximal	2	no	19.143	23.215	EPSD	COSMIC	14.606	Up-regulation
STE_STE20_PAKA_PAK2_ST	P01106	MYC	Q13177	PAK2	S337	V330L	330	Missense	distal	-7	no	24.946	24.598	EPSD	COSMIC	14.606	Down-regulation
STE_STE20_PAKA_PAK2_ST	P01106	MYC	Q13177	PAK2	S337	I336V	336	Missense	proximal	-1	no	24.946	14.883	EPSD	COSMIC	14.606	Down-regulation
STE_STE20_PAKA_PAK2_ST	P01106	MYC	Q13177	PAK2	S337	L333P	333	Missense	distal	-4	no	24.946	25.400	EPSD	COSMIC	14.606	Up-regulation
STE_STE20_PAKA_PAK2_ST	P01106	MYC	Q13177	PAK2	S337	L333V	333	Missense	distal	-4	no	24.946	25.442	EPSD	COSMIC	14.606	Up-regulation
STE_STE20_PAKA_PAK2_ST	P01106	MYC	Q13177	PAK2	T358	N360T	360	Missense	proximal	2	no	39.755	39.268	EPSD;PhosphoSitePlus	COSMIC	14.606	Down-regulation
STE_STE20_PAKA_PAK2_ST	P01106	MYC	Q13177	PAK2	T358	R364C	364	Missense	distal	6	no	39.755	40.086	EPSD;PhosphoSitePlus	COSMIC	14.606	Up-regulation
STE_STE20_PAKA_PAK2_ST	P01106	MYC	Q13177	PAK2	T358	V361A	361	Missense	distal	3	no	39.755	38.976	EPSD;PhosphoSitePlus	COSMIC	14.606	Down-regulation
STE_STE20_PAKA_PAK2_ST	P01106	MYC	Q13177	PAK2	T358	V354D	354	Missense	distal	-4	no	39.755	40.708	EPSD;PhosphoSitePlus	COSMIC	14.606	Up-regulation
STE_STE20_PAKA_PAK2_ST	P01106	MYC	Q13177	PAK2	T358	E351K	351	Missense	distal	-7	no	39.755	38.725	EPSD;PhosphoSitePlus	COSMIC	14.606	Down-regulation
STE_STE20_PAKA_PAK2_ST	P01106	MYC	Q13177	PAK2	T358	H359R	359	Missense	proximal	1	no	39.755	36.517	EPSD;PhosphoSitePlus	COSMIC	14.606	Down-regulation
STE_STE20_PAKA_PAK2_ST	P01106	MYC	Q13177	PAK2	T358	Q365K	365	Missense	distal	7	no	39.755	34.019	EPSD;PhosphoSitePlus	COSMIC	14.606	Down-regulation
STE_STE20_PAKA_PAK2_ST	P01106	MYC	Q13177	PAK2	T358	R357L	357	Missense	proximal	-1	no	39.755	41.526	EPSD;PhosphoSitePlus	COSMIC	14.606	Up-regulation
STE_STE20_PAKA_PAK2_ST	P01106	MYC	Q13177	PAK2	T358	L362S	362	Missense	distal	4	no	39.755	39.807	EPSD;PhosphoSitePlus	COSMIC	14.606	Up-regulation
STE_STE20_PAKA_PAK2_ST	P01106	MYC	Q13177	PAK2	T358	E352G	352	Missense	distal	-6	no	39.755	35.967	EPSD;PhosphoSitePlus	COSMIC	14.606	Down-regulation
STE_STE20_PAKA_PAK2_ST	P01106	MYC	Q13177	PAK2	T358	R356W	356	Missense	proximal	-2	no	39.755	9.830	EPSD;PhosphoSitePlus	COSMIC	14.606	Loss
STE_STE20_PAKA_PAK2_ST	P01106	MYC	Q13177	PAK2	T358	V361L	361	Missense	distal	3	no	39.755	38.084	EPSD;PhosphoSitePlus	COSMIC	14.606	Down-regulation
STE_STE20_PAKA_PAK2_ST	P01106	MYC	Q13177	PAK2	T358	T358R	358	Missense	central	0	yes	39.755	0.000	EPSD;PhosphoSitePlus	COSMIC	14.606	Loss
STE_STE20_PAKA_PAK2_ST	P01106	MYC	Q13177	PAK2	S373	R378C	378	Missense	distal	5	no	32.787	32.343	EPSD;PhosphoSitePlus	COSMIC	14.606	Down-regulation
STE_STE20_PAKA_PAK2_ST	P01106	MYC	Q13177	PAK2	S373	F374L	374	Missense	proximal	1	no	32.787	31.194	EPSD;PhosphoSitePlus	COSMIC	14.606	Down-regulation
STE_STE20_PAKA_PAK2_ST	P01106	MYC	Q13177	PAK2	S373	S373G	373	Missense	central	0	yes	32.787	0.000	EPSD;PhosphoSitePlus	COSMIC	14.606	Loss
STE_STE20_PAKA_PAK2_ST	P01106	MYC	Q13177	PAK2	S373	R372L	372	Missense	proximal	-1	no	32.787	34.558	EPSD;PhosphoSitePlus	COSMIC	14.606	Up-regulation
STE_STE20_PAKA_PAK2_ST	P01106	MYC	Q13177	PAK2	S373	E369K	369	Missense	distal	-4	no	32.787	32.740	EPSD;PhosphoSitePlus	COSMIC	14.606	Down-regulation
STE_STE20_PAKA_PAK2_ST	P01106	MYC	Q13177	PAK2	S373	A376V	376	Missense	distal	3	no	32.787	33.567	EPSD;PhosphoSitePlus	COSMIC	14.606	Up-regulation
STE_STE20_PAKA_PAK2_ST	P01106	MYC	Q13177	PAK2	S373	Q380H	380	Missense	distal	7	no	32.787	30.165	EPSD;PhosphoSitePlus	COSMIC	14.606	Down-regulation
STE_STE20_PAKA_PAK2_ST	P01106	MYC	Q13177	PAK2	S373	S373R	373	Missense	central	0	yes	32.787	0.000	EPSD;PhosphoSitePlus	COSMIC	14.606	Loss
STE_STE20_PAKA_PAK2_ST	P01106	MYC	Q13177	PAK2	S373	R372W	372	Missense	proximal	-1	no	32.787	29.497	EPSD;PhosphoSitePlus	COSMIC	14.606	Down-regulation
STE_STE20_PAKA_PAK2_ST	P01106	MYC	Q13177	PAK2	S373	L377S	377	Missense	distal	4	no	32.787	32.839	EPSD;PhosphoSitePlus	COSMIC	14.606	Up-regulation
STE_STE20_PAKA_PAK2_ST	P01106	MYC	Q13177	PAK2	T400	L404M	404	Missense	distal	4	no	26.109	24.690	PhosphoSitePlus;EPSD	COSMIC	14.606	Down-regulation
STE_STE20_PAKA_PAK2_ST	P01106	MYC	Q13177	PAK2	T400	S405T	405	Missense	distal	5	no	26.109	25.635	PhosphoSitePlus;EPSD	COSMIC	14.606	Down-regulation
STE_STE20_PAKA_PAK2_ST	P01106	MYC	Q13177	PAK2	T400	A399T	399	Missense	proximal	-1	no	26.109	21.512	PhosphoSitePlus;EPSD	COSMIC	14.606	Down-regulation
STE_STE20_PAKA_PAK2_ST	P49023	PXN	Q13177	PAK2	S135	V133I	133	Missense	proximal	-2	no	23.779	21.975	EPSD	COSMIC	14.606	Down-regulation
STE_STE20_PAKA_PAK2_ST	P49023	PXN	Q13177	PAK2	S135	T136M	136	Missense	proximal	1	no	23.779	25.904	EPSD	COSMIC	14.606	Up-regulation
STE_STE20_PAKA_PAK2_ST	P49023	PXN	Q13177	PAK2	S230	P231L	231	Missense	proximal	1	no	19.331	20.672	EPSD	COSMIC;CCLE	14.606	Up-regulation
STE_STE20_PAKA_PAK2_ST	P49023	PXN	Q13177	PAK2	S230	P229L	229	Missense	proximal	-1	no	19.331	27.815	EPSD	COSMIC	14.606	Up-regulation
STE_STE20_PAKA_PAK2_ST	P49023	PXN	Q13177	PAK2	S258	R256H	256	Missense	proximal	-2	no	19.957	15.001	EPSD	COSMIC	14.606	Down-regulation
STE_STE20_PAKA_PAK2_ST	P49023	PXN	Q13177	PAK2	S272	Q279K	279	Missense	distal	7	no	29.251	23.516	PhosphoSitePlus;EPSD	COSMIC	14.606	Down-regulation
STE_STE20_PAKA_PAK2_ST	P49023	PXN	Q13177	PAK2	S274	Q279K	279	Missense	distal	5	no	31.516	33.171	EPSD;PhosphoSitePlus	COSMIC	14.606	Up-regulation
STE_STE20_PAKA_PAK2_ST	P49023	PXN	Q13177	PAK2	S302	P304L	304	Missense	proximal	2	no	17.695	20.903	EPSD	COSMIC	14.606	Up-regulation
STE_STE20_PAKA_PAK2_ST	P49023	PXN	Q13177	PAK2	S302	P304R	304	Missense	proximal	2	no	17.695	17.309	EPSD	COSMIC	14.606	Down-regulation
STE_STE20_PAKA_PAK2_ST	P49023	PXN	Q13177	PAK2	S302	G300R	300	Missense	proximal	-2	no	17.695	37.023	EPSD	COSMIC	14.606	Up-regulation
STE_STE20_PAKA_PAK2_ST	P49023	PXN	Q13177	PAK2	S302	E309K	309	Missense	distal	7	no	17.695	14.990	EPSD	COSMIC	14.606	Down-regulation
STE_STE20_PAKA_PAK2_ST	P49023	PXN	Q13177	PAK2	S302	D298Y	298	Missense	distal	-4	no	17.695	15.030	EPSD	COSMIC	14.606	Down-regulation
STE_STE20_PAKA_PAK2_ST	P49023	PXN	Q13177	PAK2	S302	S303R	303	Missense	proximal	1	no	17.695	13.313	EPSD	COSMIC	14.606	Loss
STE_STE20_PAKA_PAK2_ST	P49023	PXN	Q13177	PAK2	S302	G306R	306	Missense	distal	4	no	17.695	14.228	EPSD	COSMIC	14.606	Loss
STE_STE20_PAKA_PAK2_ST	P49023	PXN	Q13177	PAK2	S302	R301Q	301	Missense	proximal	-1	no	17.695	10.521	EPSD	COSMIC	14.606	Loss
STE_STE20_PAKA_PAK2_ST	P49023	PXN	Q13177	PAK2	S302	G299S	299	Missense	distal	-3	no	17.695	11.764	EPSD	COSMIC	14.606	Loss
STE_STE20_PAKA_PAK2_ST	P49023	PXN	Q13177	PAK2	S303	P304L	304	Missense	proximal	1	no	32.352	33.694	EPSD	COSMIC	14.606	Up-regulation
STE_STE20_PAKA_PAK2_ST	P49023	PXN	Q13177	PAK2	S303	P304R	304	Missense	proximal	1	no	32.352	30.292	EPSD	COSMIC	14.606	Down-regulation
STE_STE20_PAKA_PAK2_ST	P49023	PXN	Q13177	PAK2	S303	G300R	300	Missense	distal	-3	no	32.352	37.081	EPSD	COSMIC	14.606	Up-regulation
STE_STE20_PAKA_PAK2_ST	P49023	PXN	Q13177	PAK2	S303	E309K	309	Missense	distal	6	no	32.352	32.094	EPSD	COSMIC	14.606	Down-regulation
STE_STE20_PAKA_PAK2_ST	P49023	PXN	Q13177	PAK2	S303	D298Y	298	Missense	distal	-5	no	32.352	30.116	EPSD	COSMIC	14.606	Down-regulation
STE_STE20_PAKA_PAK2_ST	P49023	PXN	Q13177	PAK2	S303	S303R	303	Missense	central	0	yes	32.352	0.000	EPSD	COSMIC	14.606	Loss
STE_STE20_PAKA_PAK2_ST	P49023	PXN	Q13177	PAK2	S303	G306R	306	Missense	distal	3	no	32.352	30.994	EPSD	COSMIC	14.606	Down-regulation
STE_STE20_PAKA_PAK2_ST	P49023	PXN	Q13177	PAK2	S303	R301Q	301	Missense	proximal	-2	no	32.352	19.443	EPSD	COSMIC	14.606	Down-regulation
STE_STE20_PAKA_PAK2_ST	P49023	PXN	Q13177	PAK2	S303	G299S	299	Missense	distal	-4	no	32.352	31.520	EPSD	COSMIC	14.606	Down-regulation
STE_STE20_PAKA_PAK2_ST	P49023	PXN	Q13177	PAK2	S320	S322A	322	Missense	proximal	2	no	19.499	13.538	EPSD	COSMIC	14.606	Loss
STE_STE20_PAKA_PAK2_ST	P49023	PXN	Q13177	PAK2	S332	P328S	328	Missense	distal	-4	no	24.417	23.790	EPSD	COSMIC	14.606	Down-regulation
STE_STE20_PAKA_PAK2_ST	P49023	PXN	Q13177	PAK2	S332	L338P	338	Missense	distal	6	no	24.417	24.669	EPSD	COSMIC	14.606	Up-regulation
STE_STE20_PAKA_PAK2_ST	P49023	PXN	Q13177	PAK2	S332	G331W	331	Missense	proximal	-1	no	24.417	25.258	EPSD	COSMIC	14.606	Up-regulation
STE_STE20_PAKA_PAK2_ST	Q05682	CALD1	Q13177	PAK2	T83	T82I	82	Missense	proximal	-1	no	20.183	22.581	EPSD	COSMIC	14.606	Up-regulation
STE_STE20_PAKA_PAK2_ST	Q05682	CALD1	Q13177	PAK2	T86	T82I	82	Missense	distal	-4	no	23.975	24.363	EPSD	COSMIC	14.606	Up-regulation
STE_STE20_PAKA_PAK2_ST	Q05682	CALD1	Q13177	PAK2	T86	D91N	91	Missense	distal	5	no	23.975	26.096	EPSD	COSMIC	14.606	Up-regulation
STE_STE20_PAKA_PAK2_ST	Q05682	CALD1	Q13177	PAK2	S129	L130P	130	Missense	proximal	1	no	17.725	16.384	EPSD	COSMIC	14.606	Down-regulation
STE_STE20_PAKA_PAK2_ST	Q05682	CALD1	Q13177	PAK2	S129	S129R	129	Missense	central	0	yes	17.725	0.000	EPSD	COSMIC	14.606	Loss
STE_STE20_PAKA_PAK2_ST	Q05682	CALD1	Q13177	PAK2	S129	D122N	122	Missense	distal	-7	no	17.725	18.831	EPSD	COSMIC	14.606	Up-regulation
STE_STE20_PAKA_PAK2_ST	Q05682	CALD1	Q13177	PAK2	S131	S129R	129	Missense	proximal	-2	no	-6.157	17.567	EPSD	COSMIC	14.606	Gain
STE_STE20_PAKA_PAK2_ST	Q05682	CALD1	Q13177	PAK2	S171	S171C	171	Missense	central	0	yes	19.578	0.000	EPSD	COSMIC	14.606	Loss
STE_STE20_PAKA_PAK2_ST	Q05682	CALD1	Q13177	PAK2	S171	V168F	168	Missense	distal	-3	no	19.578	1.801	EPSD	COSMIC	14.606	Loss
STE_STE20_PAKA_PAK2_ST	Q05682	CALD1	Q13177	PAK2	S171	Y172C	172	Missense	proximal	1	no	19.578	17.173	EPSD	COSMIC	14.606	Down-regulation
STE_STE20_PAKA_PAK2_ST	Q05682	CALD1	Q13177	PAK2	S202	K199T	199	Missense	distal	-3	no	39.887	32.737	EPSD	COSMIC	14.606	Down-regulation
STE_STE20_PAKA_PAK2_ST	Q05682	CALD1	Q13177	PAK2	S480	R484H	484	Missense	distal	4	no	20.328	19.759	EPSD	COSMIC	14.606	Down-regulation
STE_STE20_PAKA_PAK2_ST	Q05682	CALD1	Q13177	PAK2	S480	M482I	482	Missense	proximal	2	no	20.328	23.891	EPSD	COSMIC	14.606	Up-regulation
STE_STE20_PAKA_PAK2_ST	Q05682	CALD1	Q13177	PAK2	S480	R484Q	484	Missense	distal	4	no	20.328	20.628	EPSD	COSMIC	14.606	Up-regulation
STE_STE20_PAKA_PAK2_ST	Q05682	CALD1	Q13177	PAK2	S480	R484L	484	Missense	distal	4	no	20.328	19.328	EPSD	COSMIC;GDSC	14.606	Down-regulation
STE_STE20_PAKA_PAK2_ST	Q05682	CALD1	Q13177	PAK2	S480	R484G	484	Missense	distal	4	no	20.328	23.795	EPSD	COSMIC	14.606	Up-regulation
STE_STE20_PAKA_PAK2_ST	Q05682	CALD1	Q13177	PAK2	S480	E477K	477	Missense	distal	-3	no	20.328	39.342	EPSD	COSMIC	14.606	Up-regulation
STE_STE20_PAKA_PAK2_ST	Q05682	CALD1	Q13177	PAK2	S518	R512H	512	Missense	distal	-6	no	15.654	15.412	EPSD	COSMIC	14.606	Down-regulation
STE_STE20_PAKA_PAK2_ST	Q05682	CALD1	Q13177	PAK2	S642	G641S	641	Missense	proximal	-1	no	14.303	17.581	EPSD	COSMIC	14.606	Gain
STE_STE20_PAKA_PAK2_ST	Q05682	CALD1	Q13177	PAK2	S642	R649Q	649	Missense	distal	7	no	14.303	14.795	EPSD	COSMIC	14.606	Gain
STE_STE20_PAKA_PAK2_ST	Q05682	CALD1	Q13177	PAK2	S665	S661I	661	Missense	distal	-4	no	15.524	15.603	EPSD	COSMIC	14.606	Up-regulation
STE_STE20_PAKA_PAK2_ST	Q05682	CALD1	Q13177	PAK2	S714	R710G	710	Missense	distal	-4	no	30.407	31.840	EPSD;PhosphoSitePlus	COSMIC	14.606	Up-regulation
STE_STE20_PAKA_PAK2_ST	Q05682	CALD1	Q13177	PAK2	S714	V709A	709	Missense	distal	-5	no	30.407	29.823	EPSD;PhosphoSitePlus	COSMIC	14.606	Down-regulation
STE_STE20_PAKA_PAK2_ST	Q05682	CALD1	Q13177	PAK2	S714	R710C	710	Missense	distal	-4	no	30.407	30.950	EPSD;PhosphoSitePlus	COSMIC;GDSC;CCLE	14.606	Up-regulation
STE_STE20_PAKA_PAK2_ST	Q05682	CALD1	Q13177	PAK2	S714	E707K	707	Missense	distal	-7	no	30.407	29.377	EPSD;PhosphoSitePlus	COSMIC	14.606	Down-regulation
STE_STE20_PAKA_PAK2_ST	Q05682	CALD1	Q13177	PAK2	S744	R745H	745	Missense	proximal	1	no	29.070	32.308	PhosphoSitePlus;EPSD	COSMIC	14.606	Up-regulation
STE_STE20_PAKA_PAK2_ST	P55210	CASP7	Q13177	PAK2	S29	R28W	28	Missense	proximal	-1	no	19.973	16.683	EPSD	COSMIC	14.606	Down-regulation
STE_STE20_PAKA_PAK2_ST	P55210	CASP7	Q13177	PAK2	S29	S30L	30	Missense	proximal	1	no	19.973	18.993	EPSD	COSMIC	14.606	Down-regulation
STE_STE20_PAKA_PAK2_ST	P55210	CASP7	Q13177	PAK2	S29	R28Q	28	Missense	proximal	-1	no	19.973	12.799	EPSD	COSMIC	14.606	Loss
STE_STE20_PAKA_PAK2_ST	P55210	CASP7	Q13177	PAK2	S29	K25N	25	Missense	distal	-4	no	19.973	21.971	EPSD	COSMIC	14.606	Up-regulation
STE_STE20_PAKA_PAK2_ST	P55210	CASP7	Q13177	PAK2	S30	R28W	28	Missense	proximal	-2	no	33.997	4.072	PhosphoSitePlus;EPSD	COSMIC	14.606	Loss
STE_STE20_PAKA_PAK2_ST	P55210	CASP7	Q13177	PAK2	S30	S30L	30	Missense	central	0	yes	33.997	0.000	PhosphoSitePlus;EPSD	COSMIC	14.606	Loss
STE_STE20_PAKA_PAK2_ST	P55210	CASP7	Q13177	PAK2	S30	R28Q	28	Missense	proximal	-2	no	33.997	21.088	PhosphoSitePlus;EPSD	COSMIC	14.606	Down-regulation
STE_STE20_PAKA_PAK2_ST	P55210	CASP7	Q13177	PAK2	S30	K25N	25	Missense	distal	-5	no	33.997	33.124	PhosphoSitePlus;EPSD	COSMIC	14.606	Down-regulation
STE_STE20_PAKA_PAK2_ST	P55210	CASP7	Q13177	PAK2	T50	R52W	52	Missense	proximal	2	no	9.017	16.089	EPSD	COSMIC	14.606	Gain
STE_STE20_PAKA_PAK2_ST	P55210	CASP7	Q13177	PAK2	T173	L174F	174	Missense	proximal	1	no	29.180	30.773	EPSD;PhosphoSitePlus	COSMIC	14.606	Up-regulation
STE_STE20_PAKA_PAK2_ST	P55210	CASP7	Q13177	PAK2	T173	E176K	176	Missense	distal	3	no	29.180	27.779	EPSD;PhosphoSitePlus	COSMIC;CCLE	14.606	Down-regulation
STE_STE20_PAKA_PAK2_ST	P55210	CASP7	Q13177	PAK2	T173	L180F	180	Missense	distal	7	no	29.180	30.388	EPSD;PhosphoSitePlus	COSMIC	14.606	Up-regulation
STE_STE20_PAKA_PAK2_ST	P55210	CASP7	Q13177	PAK2	T173	G168S	168	Missense	distal	-5	no	29.180	29.973	EPSD;PhosphoSitePlus	COSMIC	14.606	Up-regulation
STE_STE20_PAKA_PAK2_ST	P55210	CASP7	Q13177	PAK2	S239	R233W	233	Missense	distal	-6	no	34.165	28.622	EPSD;PhosphoSitePlus	COSMIC	14.606	Down-regulation
STE_STE20_PAKA_PAK2_ST	P55210	CASP7	Q13177	PAK2	S239	W232G	232	Missense	distal	-7	no	34.165	33.425	EPSD;PhosphoSitePlus	COSMIC	14.606	Down-regulation
STE_STE20_PAKA_PAK2_ST	P55210	CASP7	Q13177	PAK2	S239	G236E	236	Missense	distal	-3	no	34.165	19.599	EPSD;PhosphoSitePlus	COSMIC	14.606	Down-regulation
STE_STE20_PAKA_PAK2_ST	P55210	CASP7	Q13177	PAK2	S239	P235S	235	Missense	distal	-4	no	34.165	33.537	EPSD;PhosphoSitePlus	COSMIC	14.606	Down-regulation
STE_STE20_PAKA_PAK2_ST	P55210	CASP7	Q13177	PAK2	S239	S234R	234	Missense	distal	-5	no	34.165	32.096	EPSD;PhosphoSitePlus	COSMIC	14.606	Down-regulation
STE_STE20_PAKA_PAK2_ST	P55210	CASP7	Q13177	PAK2	S239	S234N	234	Missense	distal	-5	no	34.165	32.830	EPSD;PhosphoSitePlus	COSMIC	14.606	Down-regulation
STE_STE20_PAKA_PAK2_ST	P55210	CASP7	Q13177	PAK2	S239	G236V	236	Missense	distal	-3	no	34.165	19.923	EPSD;PhosphoSitePlus	COSMIC	14.606	Down-regulation
STE_STE20_PAKA_PAK2_ST	Q16659	MAPK6	Q13177	PAK2	S189	W196L	196	Missense	distal	7	no	38.455	38.169	PhosphoSitePlus	COSMIC	14.606	Down-regulation
STE_STE20_PAKA_PAK2_ST	Q16659	MAPK6	Q13177	PAK2	S189	W196C	196	Missense	distal	7	no	38.455	36.933	PhosphoSitePlus	COSMIC	14.606	Down-regulation
STE_STE20_PAKA_PAK2_ST	Q16659	MAPK6	Q13177	PAK2	S189	H184R	184	Missense	distal	-5	no	38.455	38.105	PhosphoSitePlus	COSMIC	14.606	Down-regulation
STE_STE20_PAKA_PAK2_ST	Q16659	MAPK6	Q13177	PAK2	S450	K447R	447	Missense	distal	-3	no	20.229	20.510	EPSD	COSMIC	14.606	Up-regulation
STE_STE20_PAKA_PAK2_ST	Q16659	MAPK6	Q13177	PAK2	S451	K447R	447	Missense	distal	-4	no	25.098	25.294	EPSD	COSMIC	14.606	Up-regulation
STE_STE20_PAKA_PAK2_ST	Q16659	MAPK6	Q13177	PAK2	T626	D630Y	630	Missense	distal	4	no	16.415	13.529	EPSD	COSMIC	14.606	Loss
STE_STE20_PAKA_PAK2_ST	Q16659	MAPK6	Q13177	PAK2	T626	F632L	632	Missense	distal	6	no	16.415	15.660	EPSD	COSMIC	14.606	Down-regulation
STE_STE20_PAKA_PAK2_ST	Q16659	MAPK6	Q13177	PAK2	S627	F632L	632	Missense	distal	5	no	13.391	16.360	EPSD	COSMIC	14.606	Gain
STE_STE20_PAKA_PAK2_ST	Q16659	MAPK6	Q13177	PAK2	S704	P706L	706	Missense	proximal	2	no	22.003	25.212	EPSD	COSMIC	14.606	Up-regulation
STE_STE20_PAKA_PAK2_ST	Q16659	MAPK6	Q13177	PAK2	S705	P706L	706	Missense	proximal	1	no	17.680	19.022	EPSD	COSMIC	14.606	Up-regulation
STE_STE20_PAKA_PAK2_ST	P00519	ABL1	Q13177	PAK2	S59	G57E	57	Missense	proximal	-2	no	9.207	16.348	EPSD	COSMIC	14.606	Gain
STE_STE20_PAKA_PAK2_ST	P00519	ABL1	Q13177	PAK2	S265	K263N	263	Missense	proximal	-2	no	17.594	-9.619	EPSD	COSMIC	14.606	Loss
STE_STE20_PAKA_PAK2_ST	P00519	ABL1	Q13177	PAK2	S265	S265R	265	Missense	central	0	yes	17.594	0.000	EPSD	COSMIC	14.606	Loss
STE_STE20_PAKA_PAK2_ST	P00519	ABL1	Q13177	PAK2	S265	Y264C	264	Missense	proximal	-1	no	17.594	12.975	EPSD	COSMIC	14.606	Loss
STE_STE20_PAKA_PAK2_ST	P00519	ABL1	Q13177	PAK2	S265	V270M	270	Missense	distal	5	no	17.594	19.615	EPSD	COSMIC	14.606	Up-regulation
STE_STE20_PAKA_PAK2_ST	P00519	ABL1	Q13177	PAK2	S265	S265N	265	Missense	central	0	yes	17.594	0.000	EPSD	COSMIC;CCLE	14.606	Loss
STE_STE20_PAKA_PAK2_ST	P00519	ABL1	Q13177	PAK2	S265	V268L	268	Missense	distal	3	no	17.594	15.923	EPSD	COSMIC	14.606	Down-regulation
STE_STE20_PAKA_PAK2_ST	P00519	ABL1	Q13177	PAK2	S265	T267A	267	Missense	proximal	2	no	17.594	14.531	EPSD	COSMIC	14.606	Loss
STE_STE20_PAKA_PAK2_ST	P00519	ABL1	Q13177	PAK2	S265	E258A	258	Missense	distal	-7	no	17.594	17.357	EPSD	COSMIC	14.606	Down-regulation
STE_STE20_PAKA_PAK2_ST	P00519	ABL1	Q13177	PAK2	S265	E258V	258	Missense	distal	-7	no	17.594	19.042	EPSD	COSMIC	14.606	Up-regulation
STE_STE20_PAKA_PAK2_ST	P00519	ABL1	Q13177	PAK2	S265	Y264N	264	Missense	proximal	-1	no	17.594	16.213	EPSD	COSMIC	14.606	Down-regulation
STE_STE20_PAKA_PAK2_ST	P00519	ABL1	Q13177	PAK2	S265	V268A	268	Missense	distal	3	no	17.594	16.814	EPSD	COSMIC	14.606	Down-regulation
STE_STE20_PAKA_PAK2_ST	P00519	ABL1	Q13177	PAK2	S265	V260A	260	Missense	distal	-5	no	17.594	17.010	EPSD	COSMIC	14.606	Down-regulation
STE_STE20_PAKA_PAK2_ST	P00519	ABL1	Q13177	PAK2	T267	S265R	265	Missense	proximal	-2	no	-3.846	19.878	EPSD	COSMIC	14.606	Gain
STE_STE20_PAKA_PAK2_ST	P00519	ABL1	Q13177	PAK2	T394	F401L	401	Missense	distal	7	no	20.086	18.877	EPSD	COSMIC	14.606	Down-regulation
STE_STE20_PAKA_PAK2_ST	P00519	ABL1	Q13177	PAK2	T394	A397P	397	Missense	distal	3	no	20.086	21.436	EPSD	COSMIC	14.606	Up-regulation
STE_STE20_PAKA_PAK2_ST	P00519	ABL1	Q13177	PAK2	T394	H396R	396	Missense	proximal	2	no	20.086	16.888	EPSD	COSMIC	14.606	Down-regulation
STE_STE20_PAKA_PAK2_ST	P00519	ABL1	Q13177	PAK2	T394	L387M	387	Missense	distal	-7	no	20.086	18.491	EPSD	COSMIC	14.606	Down-regulation
STE_STE20_PAKA_PAK2_ST	P00519	ABL1	Q13177	PAK2	T394	M388L	388	Missense	distal	-6	no	20.086	16.765	EPSD	COSMIC	14.606	Down-regulation
STE_STE20_PAKA_PAK2_ST	P00519	ABL1	Q13177	PAK2	T394	G398R	398	Missense	distal	4	no	20.086	16.618	EPSD	COSMIC	14.606	Down-regulation
STE_STE20_PAKA_PAK2_ST	P00519	ABL1	Q13177	PAK2	T394	A399T	399	Missense	distal	5	no	20.086	19.048	EPSD	COSMIC	14.606	Down-regulation
STE_STE20_PAKA_PAK2_ST	P00519	ABL1	Q13177	PAK2	T394	T389A	389	Missense	distal	-5	no	20.086	17.358	EPSD	COSMIC	14.606	Down-regulation
STE_STE20_PAKA_PAK2_ST	P00519	ABL1	Q13177	PAK2	T394	K400E	400	Missense	distal	6	no	20.086	20.343	EPSD	COSMIC	14.606	Up-regulation
STE_STE20_PAKA_PAK2_ST	P00519	ABL1	Q13177	PAK2	T394	T394A	394	Missense	central	0	yes	20.086	0.000	EPSD	COSMIC	14.606	Loss
STE_STE20_PAKA_PAK2_ST	P00519	ABL1	Q13177	PAK2	T394	H396P	396	Missense	proximal	2	no	20.086	17.274	EPSD	COSMIC	14.606	Down-regulation
STE_STE20_PAKA_PAK2_ST	P00519	ABL1	Q13177	PAK2	T394	D391N	391	Missense	distal	-3	no	20.086	18.353	EPSD	COSMIC	14.606	Down-regulation
STE_STE20_PAKA_PAK2_ST	P00519	ABL1	Q13177	PAK2	T394	L387F	387	Missense	distal	-7	no	20.086	20.926	EPSD	COSMIC	14.606	Up-regulation
STE_STE20_PAKA_PAK2_ST	P00519	ABL1	Q13177	PAK2	T394	H396Y	396	Missense	proximal	2	no	20.086	29.379	EPSD	COSMIC	14.606	Up-regulation
STE_STE20_PAKA_PAK2_ST	P00519	ABL1	Q13177	PAK2	T394	G390W	390	Missense	distal	-4	no	20.086	19.969	EPSD	COSMIC	14.606	Down-regulation
STE_STE20_PAKA_PAK2_ST	P00519	ABL1	Q13177	PAK2	S618	K616R	616	Missense	proximal	-2	no	28.019	36.673	EPSD;PhosphoSitePlus	COSMIC	14.606	Up-regulation
STE_STE20_PAKA_PAK2_ST	P00519	ABL1	Q13177	PAK2	S619	G626D	626	Missense	distal	7	no	51.499	53.407	PhosphoSitePlus;EPSD	COSMIC	14.606	Up-regulation
STE_STE20_PAKA_PAK2_ST	P00519	ABL1	Q13177	PAK2	S619	G626S	626	Missense	distal	7	no	51.499	46.207	PhosphoSitePlus;EPSD	COSMIC	14.606	Down-regulation
STE_STE20_PAKA_PAK2_ST	P00519	ABL1	Q13177	PAK2	S619	K616R	616	Missense	distal	-3	no	51.499	51.780	PhosphoSitePlus;EPSD	COSMIC	14.606	Up-regulation
STE_STE20_PAKA_PAK2_ST	P00519	ABL1	Q13177	PAK2	S642	G644V	644	Missense	proximal	2	no	12.417	22.114	EPSD	COSMIC	14.606	Gain
STE_STE20_PAKA_PAK2_ST	P00519	ABL1	Q13177	PAK2	S663	P669L	669	Missense	distal	6	no	14.971	14.719	EPSD	COSMIC	14.606	Down-regulation
STE_STE20_PAKA_PAK2_ST	P00519	ABL1	Q13177	PAK2	S663	N670S	670	Missense	distal	7	no	14.971	10.078	EPSD	COSMIC	14.606	Loss
STE_STE20_PAKA_PAK2_ST	P00519	ABL1	Q13177	PAK2	S663	P662L	662	Missense	proximal	-1	no	14.971	23.455	EPSD	COSMIC;CCLE	14.606	Up-regulation
STE_STE20_PAKA_PAK2_ST	P00519	ABL1	Q13177	PAK2	S663	P669S	669	Missense	distal	6	no	14.971	13.943	EPSD	COSMIC;CCLE	14.606	Loss
STE_STE20_PAKA_PAK2_ST	P00519	ABL1	Q13177	PAK2	S663	S663R	663	Missense	central	0	yes	14.971	0.000	EPSD	COSMIC	14.606	Loss
STE_STE20_PAKA_PAK2_ST	P00519	ABL1	Q13177	PAK2	S663	G665L	665	Missense	proximal	2	no	14.971	18.636	EPSD	COSMIC	14.606	Up-regulation
STE_STE20_PAKA_PAK2_ST	P00519	ABL1	Q13177	PAK2	S663	K658N	658	Missense	distal	-5	no	14.971	14.098	EPSD	COSMIC	14.606	Loss
STE_STE20_PAKA_PAK2_ST	P00519	ABL1	Q13177	PAK2	S679	G677R	677	Missense	proximal	-2	no	-2.431	16.897	EPSD	COSMIC	14.606	Gain
STE_STE20_PAKA_PAK2_ST	P00519	ABL1	Q13177	PAK2	T779	P783L	783	Missense	distal	4	no	14.837	13.041	EPSD	COSMIC	14.606	Loss
STE_STE20_PAKA_PAK2_ST	P00519	ABL1	Q13177	PAK2	S804	V797I	797	Missense	distal	-7	no	16.642	16.096	EPSD	COSMIC	14.606	Down-regulation
STE_STE20_PAKA_PAK2_ST	P00519	ABL1	Q13177	PAK2	S804	G807S	807	Missense	distal	3	no	16.642	11.310	EPSD	COSMIC	14.606	Loss
STE_STE20_PAKA_PAK2_ST	P00519	ABL1	Q13177	PAK2	S804	P806L	806	Missense	proximal	2	no	16.642	19.851	EPSD	COSMIC	14.606	Up-regulation
STE_STE20_PAKA_PAK2_ST	P00519	ABL1	Q13177	PAK2	S828	H832D	832	Missense	distal	4	no	13.577	16.244	EPSD	COSMIC	14.606	Gain
STE_STE20_PAKA_PAK2_ST	P00519	ABL1	Q13177	PAK2	S936	S943T	943	Missense	distal	7	no	14.636	18.798	EPSD	COSMIC	14.606	Up-regulation
STE_STE20_PAKA_PAK2_ST	P00519	ABL1	Q13177	PAK2	T963	P961Q	961	Missense	proximal	-2	no	15.429	11.845	EPSD	COSMIC	14.606	Loss
STE_STE20_PAKA_PAK2_ST	P00519	ABL1	Q13177	PAK2	T963	V959M	959	Missense	distal	-4	no	15.429	13.529	EPSD	COSMIC	14.606	Loss
STE_STE20_PAKA_PAK2_ST	P35240	NF2	Q13177	PAK2	T180	E182V	182	Missense	proximal	2	no	2.991	15.758	EPSD	COSMIC	14.606	Gain
STE_STE20_PAKA_PAK2_ST	P35240	NF2	Q13177	PAK2	T189	E186D	186	Missense	distal	-3	no	9.643	16.279	EPSD	COSMIC	14.606	Gain
STE_STE20_PAKA_PAK2_ST	P35240	NF2	Q13177	PAK2	T251	E247K	247	Missense	distal	-4	no	23.380	23.333	EPSD	COSMIC	14.606	Down-regulation
STE_STE20_PAKA_PAK2_ST	P35240	NF2	Q13177	PAK2	T251	K253N	253	Missense	proximal	2	no	23.380	25.612	EPSD	COSMIC	14.606	Up-regulation
STE_STE20_PAKA_PAK2_ST	P35240	NF2	Q13177	PAK2	T251	P257L	257	Missense	distal	6	no	23.380	23.128	EPSD	COSMIC	14.606	Down-regulation
STE_STE20_PAKA_PAK2_ST	P35240	NF2	Q13177	PAK2	T251	P257Q	257	Missense	distal	6	no	23.380	23.778	EPSD	COSMIC	14.606	Up-regulation
STE_STE20_PAKA_PAK2_ST	P35240	NF2	Q13177	PAK2	T251	R249C	249	Missense	proximal	-2	no	23.380	11.778	EPSD	COSMIC	14.606	Loss
STE_STE20_PAKA_PAK2_ST	P35240	NF2	Q13177	PAK2	T251	R249H	249	Missense	proximal	-2	no	23.380	18.423	EPSD	COSMIC	14.606	Down-regulation
STE_STE20_PAKA_PAK2_ST	P35240	NF2	Q13177	PAK2	T251	R249P	249	Missense	proximal	-2	no	23.380	14.055	EPSD	COSMIC	14.606	Loss
STE_STE20_PAKA_PAK2_ST	P35240	NF2	Q13177	PAK2	S255	R262Q	262	Missense	distal	7	no	24.681	25.174	EPSD	COSMIC	14.606	Up-regulation
STE_STE20_PAKA_PAK2_ST	P35240	NF2	Q13177	PAK2	S255	K253N	253	Missense	proximal	-2	no	24.681	-2.532	EPSD	COSMIC	14.606	Loss
STE_STE20_PAKA_PAK2_ST	P35240	NF2	Q13177	PAK2	S255	P257L	257	Missense	proximal	2	no	24.681	27.890	EPSD	COSMIC	14.606	Up-regulation
STE_STE20_PAKA_PAK2_ST	P35240	NF2	Q13177	PAK2	S255	P257Q	257	Missense	proximal	2	no	24.681	27.948	EPSD	COSMIC	14.606	Up-regulation
STE_STE20_PAKA_PAK2_ST	P35240	NF2	Q13177	PAK2	S255	R249C	249	Missense	distal	-6	no	24.681	20.091	EPSD	COSMIC	14.606	Down-regulation
STE_STE20_PAKA_PAK2_ST	P35240	NF2	Q13177	PAK2	S255	R249H	249	Missense	distal	-6	no	24.681	24.439	EPSD	COSMIC	14.606	Down-regulation
STE_STE20_PAKA_PAK2_ST	P35240	NF2	Q13177	PAK2	S255	R249P	249	Missense	distal	-6	no	24.681	21.573	EPSD	COSMIC	14.606	Down-regulation
STE_STE20_PAKA_PAK2_ST	P35240	NF2	Q13177	PAK2	S265	R262Q	262	Missense	distal	-3	no	26.682	9.540	EPSD	COSMIC	14.606	Loss
STE_STE20_PAKA_PAK2_ST	P35240	NF2	Q13177	PAK2	S265	E270D	270	Missense	distal	5	no	26.682	23.125	EPSD	COSMIC	14.606	Down-regulation
STE_STE20_PAKA_PAK2_ST	P35240	NF2	Q13177	PAK2	T415	A416E	416	Missense	proximal	1	no	16.554	16.258	EPSD	COSMIC	14.606	Down-regulation
STE_STE20_PAKA_PAK2_ST	P35240	NF2	Q13177	PAK2	T415	E421K	421	Missense	distal	6	no	16.554	16.297	EPSD	COSMIC	14.606	Down-regulation
STE_STE20_PAKA_PAK2_ST	P35240	NF2	Q13177	PAK2	T415	E408D	408	Missense	distal	-7	no	16.554	17.449	EPSD	COSMIC	14.606	Up-regulation
STE_STE20_PAKA_PAK2_ST	P35240	NF2	Q13177	PAK2	T415	R418G	418	Missense	distal	3	no	16.554	17.912	EPSD	COSMIC	14.606	Up-regulation
STE_STE20_PAKA_PAK2_ST	P35240	NF2	Q13177	PAK2	T415	E421D	421	Missense	distal	6	no	16.554	17.049	EPSD	COSMIC	14.606	Up-regulation
STE_STE20_PAKA_PAK2_ST	P35240	NF2	Q13177	PAK2	T415	E422K	422	Missense	distal	7	no	16.554	13.850	EPSD	COSMIC	14.606	Loss
STE_STE20_PAKA_PAK2_ST	P35240	NF2	Q13177	PAK2	S518	T512S	512	Missense	distal	-6	no	42.102	39.879	PhosphoSitePlus	COSMIC	14.606	Down-regulation
STE_STE20_PAKA_PAK2_ST	P35240	NF2	Q13177	PAK2	S518	M514V	514	Missense	distal	-4	no	42.102	44.002	PhosphoSitePlus	COSMIC	14.606	Up-regulation
STE_STE20_PAKA_PAK2_ST	P35240	NF2	Q13177	PAK2	S518	S518F	518	Missense	central	0	yes	42.102	0.000	PhosphoSitePlus	COSMIC	14.606	Loss
STE_STE20_PAKA_PAK2_ST	P35240	NF2	Q13177	PAK2	S518	D511H	511	Missense	distal	-7	no	42.102	40.159	PhosphoSitePlus	COSMIC	14.606	Down-regulation
STE_STE20_PAKA_PAK2_ST	P35240	NF2	Q13177	PAK2	S518	E520D	520	Missense	proximal	2	no	42.102	38.655	PhosphoSitePlus	COSMIC	14.606	Down-regulation
STE_STE20_PAKA_PAK2_ST	P35240	NF2	Q13177	PAK2	S518	E522K	522	Missense	distal	4	no	42.102	42.986	PhosphoSitePlus	COSMIC	14.606	Up-regulation
STE_STE20_PAKA_PAK2_ST	P35240	NF2	Q13177	PAK2	S518	E522Q	522	Missense	distal	4	no	42.102	42.814	PhosphoSitePlus	COSMIC	14.606	Up-regulation
STE_STE20_PAKA_PAK2_ST	P35240	NF2	Q13177	PAK2	S518	L517V	517	Missense	proximal	-1	no	42.102	30.840	PhosphoSitePlus	COSMIC	14.606	Down-regulation
STE_STE20_PAKA_PAK2_ST	Q15796	SMAD2	Q13177	PAK2	S47	K53E	53	Missense	distal	6	no	21.511	21.769	EPSD	COSMIC	14.606	Up-regulation
STE_STE20_PAKA_PAK2_ST	Q15796	SMAD2	Q13177	PAK2	S47	W40G	40	Missense	distal	-7	no	21.511	20.772	EPSD	COSMIC	14.606	Down-regulation
STE_STE20_PAKA_PAK2_ST	Q15796	SMAD2	Q13177	PAK2	S47	A44T	44	Missense	distal	-3	no	21.511	17.760	EPSD	COSMIC	14.606	Down-regulation
STE_STE20_PAKA_PAK2_ST	Q15796	SMAD2	Q13177	PAK2	S47	K54T	54	Missense	distal	7	no	21.511	25.857	EPSD	COSMIC	14.606	Up-regulation
STE_STE20_PAKA_PAK2_ST	Q15796	SMAD2	Q13177	PAK2	S47	E42Q	42	Missense	distal	-5	no	21.511	22.900	EPSD	COSMIC	14.606	Up-regulation
STE_STE20_PAKA_PAK2_ST	Q15796	SMAD2	Q13177	PAK2	T172	Y165D	165	Missense	distal	-7	no	19.293	20.192	EPSD	COSMIC	14.606	Up-regulation
STE_STE20_PAKA_PAK2_ST	Q15796	SMAD2	Q13177	PAK2	T172	P177S	177	Missense	distal	5	no	19.293	20.839	EPSD	COSMIC;GDSC;CCLE	14.606	Up-regulation
STE_STE20_PAKA_PAK2_ST	Q15796	SMAD2	Q13177	PAK2	T172	R169G	169	Missense	distal	-3	no	19.293	14.564	EPSD	COSMIC	14.606	Loss
STE_STE20_PAKA_PAK2_ST	Q15796	SMAD2	Q13177	PAK2	T172	Y167C	167	Missense	distal	-5	no	19.293	21.623	EPSD	COSMIC	14.606	Up-regulation
STE_STE20_PAKA_PAK2_ST	Q15796	SMAD2	Q13177	PAK2	T172	H166Q	166	Missense	distal	-6	no	19.293	16.423	EPSD	COSMIC	14.606	Down-regulation
STE_STE20_PAKA_PAK2_ST	Q15796	SMAD2	Q13177	PAK2	T172	Y165F	165	Missense	distal	-7	no	19.293	21.238	EPSD	COSMIC	14.606	Up-regulation
STE_STE20_PAKA_PAK2_ST	Q15796	SMAD2	Q13177	PAK2	T197	D195H	195	Missense	proximal	-2	no	9.768	17.447	EPSD	COSMIC	14.606	Gain
STE_STE20_PAKA_PAK2_ST	Q15796	SMAD2	Q13177	PAK2	S417	M416V	416	Missense	proximal	-1	no	32.504	15.429	PhosphoSitePlus	COSMIC	14.606	Down-regulation
STE_STE20_PAKA_PAK2_ST	Q15796	SMAD2	Q13177	PAK2	S417	M416R	416	Missense	proximal	-1	no	32.504	24.920	PhosphoSitePlus	COSMIC	14.606	Down-regulation
STE_STE20_PAKA_PAK2_ST	Q15796	SMAD2	Q13177	PAK2	S417	R410G	410	Missense	distal	-7	no	32.504	33.504	PhosphoSitePlus	COSMIC	14.606	Up-regulation
STE_STE20_PAKA_PAK2_ST	Q15796	SMAD2	Q13177	PAK2	S417	K420Q	420	Missense	distal	3	no	32.504	32.995	PhosphoSitePlus	COSMIC	14.606	Up-regulation
STE_STE20_PAKA_PAK2_ST	Q15796	SMAD2	Q13177	PAK2	S417	S417N	417	Missense	central	0	yes	32.504	0.000	PhosphoSitePlus	COSMIC	14.606	Loss
STE_STE20_PAKA_PAK2_ST	Q15796	SMAD2	Q13177	PAK2	S417	T413N	413	Missense	distal	-4	no	32.504	34.013	PhosphoSitePlus	COSMIC	14.606	Up-regulation
STE_STE20_PAKA_PAK2_ST	Q15796	SMAD2	Q13177	PAK2	T430	S433N	433	Missense	distal	3	no	25.015	28.429	EPSD	COSMIC	14.606	Up-regulation
STE_STE20_PAKA_PAK2_ST	Q15796	SMAD2	Q13177	PAK2	T430	V431A	431	Missense	proximal	1	no	25.015	23.459	EPSD	COSMIC	14.606	Down-regulation
STE_STE20_PAKA_PAK2_ST	Q15796	SMAD2	Q13177	PAK2	T430	T432I	432	Missense	proximal	2	no	25.015	26.744	EPSD	COSMIC	14.606	Up-regulation
STE_STE20_PAKA_PAK2_ST	Q15796	SMAD2	Q13177	PAK2	T430	R427Q	427	Missense	distal	-3	no	25.015	7.873	EPSD	COSMIC	14.606	Loss
STE_STE20_PAKA_PAK2_ST	Q15796	SMAD2	Q13177	PAK2	T430	S433R	433	Missense	distal	3	no	25.015	28.990	EPSD	COSMIC	14.606	Up-regulation
STE_STE20_PAKA_PAK2_ST	Q15796	SMAD2	Q13177	PAK2	T430	T430M	430	Missense	central	0	yes	25.015	0.000	EPSD	COSMIC	14.606	Loss
STE_STE20_PAKA_PAK2_ST	Q15796	SMAD2	Q13177	PAK2	T430	C436W	436	Missense	distal	6	no	25.015	24.185	EPSD	COSMIC	14.606	Down-regulation
STE_STE20_PAKA_PAK2_ST	Q15796	SMAD2	Q13177	PAK2	S465	C463Y	463	Missense	proximal	-2	no	12.394	14.947	EPSD	COSMIC	14.606	Gain
STE_STE20_PAKA_PAK2_ST	Q15796	SMAD2	Q13177	PAK2	S465	P459H	459	Missense	distal	-6	no	12.394	15.259	EPSD	COSMIC	14.606	Gain
STE_STE20_PAKA_PAK2_ST	Q15796	SMAD2	Q13177	PAK2	S465	S464L	464	Missense	proximal	-1	no	12.394	15.018	EPSD	COSMIC	14.606	Gain
STE_STE20_PAKA_PAK2_ST	Q04637	EIF4G1	Q13177	PAK2	S204	G199D	199	Missense	distal	-5	no	27.843	28.909	EPSD	COSMIC	14.606	Up-regulation
STE_STE20_PAKA_PAK2_ST	Q04637	EIF4G1	Q13177	PAK2	S204	P208L	208	Missense	distal	4	no	27.843	26.046	EPSD	COSMIC	14.606	Down-regulation
STE_STE20_PAKA_PAK2_ST	Q04637	EIF4G1	Q13177	PAK2	S204	R201C	201	Missense	distal	-3	no	27.843	10.662	EPSD	COSMIC	14.606	Loss
STE_STE20_PAKA_PAK2_ST	Q04637	EIF4G1	Q13177	PAK2	S204	R201H	201	Missense	distal	-3	no	27.843	13.000	EPSD	COSMIC	14.606	Loss
STE_STE20_PAKA_PAK2_ST	Q04637	EIF4G1	Q13177	PAK2	S204	T211M	211	Missense	distal	7	no	27.843	23.303	EPSD	COSMIC	14.606	Down-regulation
STE_STE20_PAKA_PAK2_ST	Q04637	EIF4G1	Q13177	PAK2	S314	P315S	315	Missense	proximal	1	no	19.342	21.664	EPSD	COSMIC	14.606	Up-regulation
STE_STE20_PAKA_PAK2_ST	Q04637	EIF4G1	Q13177	PAK2	S314	R312H	312	Missense	proximal	-2	no	19.342	14.386	EPSD	COSMIC	14.606	Loss
STE_STE20_PAKA_PAK2_ST	Q04637	EIF4G1	Q13177	PAK2	S332	T330R	330	Missense	proximal	-2	no	11.768	19.504	EPSD	COSMIC	14.606	Gain
STE_STE20_PAKA_PAK2_ST	Q04637	EIF4G1	Q13177	PAK2	T489	A493T	493	Missense	distal	4	no	14.061	15.057	EPSD	COSMIC	14.606	Gain
STE_STE20_PAKA_PAK2_ST	Q04637	EIF4G1	Q13177	PAK2	T677	S679F	679	Missense	proximal	2	no	22.455	26.528	EPSD	COSMIC	14.606	Up-regulation
STE_STE20_PAKA_PAK2_ST	Q04637	EIF4G1	Q13177	PAK2	T677	R675H	675	Missense	proximal	-2	no	22.455	17.498	EPSD	COSMIC	14.606	Down-regulation
STE_STE20_PAKA_PAK2_ST	Q04637	EIF4G1	Q13177	PAK2	T677	R681H	681	Missense	distal	4	no	22.455	21.886	EPSD	COSMIC	14.606	Down-regulation
STE_STE20_PAKA_PAK2_ST	Q04637	EIF4G1	Q13177	PAK2	T677	R675Q	675	Missense	proximal	-2	no	22.455	9.546	EPSD	COSMIC	14.606	Loss
STE_STE20_PAKA_PAK2_ST	Q04637	EIF4G1	Q13177	PAK2	T677	R681Q	681	Missense	distal	4	no	22.455	22.755	EPSD	COSMIC	14.606	Up-regulation
STE_STE20_PAKA_PAK2_ST	Q04637	EIF4G1	Q13177	PAK2	S679	S679F	679	Missense	central	0	yes	16.493	0.000	EPSD	COSMIC	14.606	Loss
STE_STE20_PAKA_PAK2_ST	Q04637	EIF4G1	Q13177	PAK2	S679	R675H	675	Missense	distal	-4	no	16.493	15.646	EPSD	COSMIC	14.606	Down-regulation
STE_STE20_PAKA_PAK2_ST	Q04637	EIF4G1	Q13177	PAK2	S679	G686D	686	Missense	distal	7	no	16.493	18.401	EPSD	COSMIC	14.606	Up-regulation
STE_STE20_PAKA_PAK2_ST	Q04637	EIF4G1	Q13177	PAK2	S679	R681H	681	Missense	proximal	2	no	16.493	19.691	EPSD	COSMIC	14.606	Up-regulation
STE_STE20_PAKA_PAK2_ST	Q04637	EIF4G1	Q13177	PAK2	S679	R675Q	675	Missense	distal	-4	no	16.493	16.566	EPSD	COSMIC	14.606	Up-regulation
STE_STE20_PAKA_PAK2_ST	Q04637	EIF4G1	Q13177	PAK2	S679	R681Q	681	Missense	proximal	2	no	16.493	20.145	EPSD	COSMIC	14.606	Up-regulation
STE_STE20_PAKA_PAK2_ST	Q04637	EIF4G1	Q13177	PAK2	S766	L768M	768	Missense	proximal	2	no	26.595	25.567	EPSD	COSMIC	14.606	Down-regulation
STE_STE20_PAKA_PAK2_ST	Q04637	EIF4G1	Q13177	PAK2	S766	S766F	766	Missense	central	0	yes	26.595	0.000	EPSD	COSMIC	14.606	Loss
STE_STE20_PAKA_PAK2_ST	Q04637	EIF4G1	Q13177	PAK2	S766	R762H	762	Missense	distal	-4	no	26.595	25.749	EPSD	COSMIC;CCLE	14.606	Down-regulation
STE_STE20_PAKA_PAK2_ST	Q04637	EIF4G1	Q13177	PAK2	S766	L771P	771	Missense	distal	5	no	26.595	23.568	EPSD	COSMIC	14.606	Down-regulation
STE_STE20_PAKA_PAK2_ST	Q04637	EIF4G1	Q13177	PAK2	S766	D759Y	759	Missense	distal	-7	no	26.595	25.696	EPSD	COSMIC	14.606	Down-regulation
STE_STE20_PAKA_PAK2_ST	Q04637	EIF4G1	Q13177	PAK2	S766	R763H	763	Missense	distal	-3	no	26.595	11.752	EPSD	COSMIC	14.606	Loss
STE_STE20_PAKA_PAK2_ST	Q04637	EIF4G1	Q13177	PAK2	S895	G897E	897	Missense	proximal	2	no	31.597	28.526	PhosphoSitePlus	COSMIC	14.606	Down-regulation
STE_STE20_PAKA_PAK2_ST	Q04637	EIF4G1	Q13177	PAK2	S895	G897R	897	Missense	proximal	2	no	31.597	31.667	PhosphoSitePlus	COSMIC;GDSC	14.606	Up-regulation
STE_STE20_PAKA_PAK2_ST	Q04637	EIF4G1	Q13177	PAK2	S895	R888Q	888	Missense	distal	-7	no	31.597	31.688	PhosphoSitePlus	COSMIC	14.606	Up-regulation
STE_STE20_PAKA_PAK2_ST	Q04637	EIF4G1	Q13177	PAK2	S895	R894C	894	Missense	proximal	-1	no	31.597	23.336	PhosphoSitePlus	COSMIC	14.606	Down-regulation
STE_STE20_PAKA_PAK2_ST	Q04637	EIF4G1	Q13177	PAK2	S895	R893W	893	Missense	proximal	-2	no	31.597	1.672	PhosphoSitePlus	COSMIC	14.606	Loss
STE_STE20_PAKA_PAK2_ST	Q04637	EIF4G1	Q13177	PAK2	S895	I890V	890	Missense	distal	-5	no	31.597	30.144	PhosphoSitePlus	COSMIC	14.606	Down-regulation
STE_STE20_PAKA_PAK2_ST	Q04637	EIF4G1	Q13177	PAK2	S895	R894H	894	Missense	proximal	-1	no	31.597	26.235	PhosphoSitePlus	COSMIC;GDSC;CCLE	14.606	Down-regulation
STE_STE20_PAKA_PAK2_ST	Q04637	EIF4G1	Q13177	PAK2	S895	I902V	902	Missense	distal	7	no	31.597	33.932	PhosphoSitePlus	COSMIC	14.606	Up-regulation
STE_STE20_PAKA_PAK2_ST	Q04637	EIF4G1	Q13177	PAK2	S895	R888H	888	Missense	distal	-7	no	31.597	30.733	PhosphoSitePlus	COSMIC	14.606	Down-regulation
STE_STE20_PAKA_PAK2_ST	Q04637	EIF4G1	Q13177	PAK2	S895	R894W	894	Missense	proximal	-1	no	31.597	28.306	PhosphoSitePlus	COSMIC	14.606	Down-regulation
STE_STE20_PAKA_PAK2_ST	Q04637	EIF4G1	Q13177	PAK2	S895	L896P	896	Missense	proximal	1	no	31.597	30.255	PhosphoSitePlus	COSMIC	14.606	Down-regulation
STE_STE20_PAKA_PAK2_ST	Q04637	EIF4G1	Q13177	PAK2	T1001	D1003Y	1003	Missense	proximal	2	no	0.346	19.425	EPSD	COSMIC;GDSC;CCLE	14.606	Gain
STE_STE20_PAKA_PAK2_ST	Q04637	EIF4G1	Q13177	PAK2	T1054	W1052R	1052	Missense	proximal	-2	no	-10.274	19.651	EPSD	COSMIC	14.606	Gain
STE_STE20_PAKA_PAK2_ST	Q04637	EIF4G1	Q13177	PAK2	S1092	L1091R	1091	Missense	proximal	-1	no	28.254	26.483	EPSD	COSMIC	14.606	Down-regulation
STE_STE20_PAKA_PAK2_ST	Q04637	EIF4G1	Q13177	PAK2	S1092	G1089W	1089	Missense	distal	-3	no	28.254	14.582	EPSD	COSMIC	14.606	Loss
STE_STE20_PAKA_PAK2_ST	Q04637	EIF4G1	Q13177	PAK2	S1092	G1096D	1096	Missense	distal	4	no	28.254	26.884	EPSD	COSMIC	14.606	Down-regulation
STE_STE20_PAKA_PAK2_ST	Q04637	EIF4G1	Q13177	PAK2	S1092	P1087S	1087	Missense	distal	-5	no	28.254	27.343	EPSD	COSMIC	14.606	Down-regulation
STE_STE20_PAKA_PAK2_ST	Q04637	EIF4G1	Q13177	PAK2	S1092	S1097I	1097	Missense	distal	5	no	28.254	26.923	EPSD	COSMIC	14.606	Down-regulation
STE_STE20_PAKA_PAK2_ST	Q04637	EIF4G1	Q13177	PAK2	S1092	S1098I	1098	Missense	distal	6	no	28.254	29.928	EPSD	COSMIC	14.606	Up-regulation
STE_STE20_PAKA_PAK2_ST	Q04637	EIF4G1	Q13177	PAK2	S1097	L1091R	1091	Missense	distal	-6	no	14.282	17.747	EPSD	COSMIC	14.606	Gain
STE_STE20_PAKA_PAK2_ST	Q04637	EIF4G1	Q13177	PAK2	S1097	G1102R	1102	Missense	distal	5	no	14.282	15.480	EPSD	COSMIC	14.606	Gain
STE_STE20_PAKA_PAK2_ST	Q04637	EIF4G1	Q13177	PAK2	S1097	G1096D	1096	Missense	proximal	-1	no	14.282	19.801	EPSD	COSMIC	14.606	Gain
STE_STE20_PAKA_PAK2_ST	Q04637	EIF4G1	Q13177	PAK2	S1098	L1091R	1091	Missense	distal	-7	no	16.332	15.047	EPSD	COSMIC	14.606	Down-regulation
STE_STE20_PAKA_PAK2_ST	Q04637	EIF4G1	Q13177	PAK2	S1098	G1102R	1102	Missense	distal	4	no	16.332	12.864	EPSD	COSMIC	14.606	Loss
STE_STE20_PAKA_PAK2_ST	Q04637	EIF4G1	Q13177	PAK2	S1098	P1105H	1105	Missense	distal	7	no	16.332	15.939	EPSD	COSMIC	14.606	Down-regulation
STE_STE20_PAKA_PAK2_ST	Q04637	EIF4G1	Q13177	PAK2	S1098	G1096D	1096	Missense	proximal	-2	no	16.332	23.024	EPSD	COSMIC	14.606	Up-regulation
STE_STE20_PAKA_PAK2_ST	Q04637	EIF4G1	Q13177	PAK2	S1098	S1097I	1097	Missense	proximal	-1	no	16.332	17.758	EPSD	COSMIC	14.606	Up-regulation
STE_STE20_PAKA_PAK2_ST	Q04637	EIF4G1	Q13177	PAK2	S1098	A1103P	1103	Missense	distal	5	no	16.332	14.222	EPSD	COSMIC	14.606	Loss
STE_STE20_PAKA_PAK2_ST	Q04637	EIF4G1	Q13177	PAK2	S1098	S1098I	1098	Missense	central	0	yes	16.332	0.000	EPSD	COSMIC	14.606	Loss
STE_STE20_PAKA_PAK2_ST	Q04637	EIF4G1	Q13177	PAK2	S1106	S1110F	1110	Missense	distal	4	no	23.858	26.017	EPSD	COSMIC	14.606	Up-regulation
STE_STE20_PAKA_PAK2_ST	Q04637	EIF4G1	Q13177	PAK2	S1106	S1110P	1110	Missense	distal	4	no	23.858	25.603	EPSD	COSMIC	14.606	Up-regulation
STE_STE20_PAKA_PAK2_ST	Q04637	EIF4G1	Q13177	PAK2	S1106	G1102R	1102	Missense	distal	-4	no	23.858	22.424	EPSD	COSMIC	14.606	Down-regulation
STE_STE20_PAKA_PAK2_ST	Q04637	EIF4G1	Q13177	PAK2	S1106	P1105H	1105	Missense	proximal	-1	no	23.858	25.210	EPSD	COSMIC	14.606	Up-regulation
STE_STE20_PAKA_PAK2_ST	Q04637	EIF4G1	Q13177	PAK2	S1106	A1109V	1109	Missense	distal	3	no	23.858	24.638	EPSD	COSMIC	14.606	Up-regulation
STE_STE20_PAKA_PAK2_ST	Q04637	EIF4G1	Q13177	PAK2	S1106	A1108T	1108	Missense	proximal	2	no	23.858	26.921	EPSD	COSMIC	14.606	Up-regulation
STE_STE20_PAKA_PAK2_ST	Q04637	EIF4G1	Q13177	PAK2	S1106	S1106P	1106	Missense	central	0	yes	23.858	0.000	EPSD	COSMIC	14.606	Loss
STE_STE20_PAKA_PAK2_ST	Q04637	EIF4G1	Q13177	PAK2	S1106	A1103P	1103	Missense	distal	-3	no	23.858	17.933	EPSD	COSMIC	14.606	Down-regulation
STE_STE20_PAKA_PAK2_ST	Q04637	EIF4G1	Q13177	PAK2	S1106	A1109T	1109	Missense	distal	3	no	23.858	23.811	EPSD	COSMIC	14.606	Down-regulation
STE_STE20_PAKA_PAK2_ST	Q04637	EIF4G1	Q13177	PAK2	T1117	A1116V	1116	Missense	proximal	-1	no	22.105	9.843	EPSD	COSMIC	14.606	Loss
STE_STE20_PAKA_PAK2_ST	Q04637	EIF4G1	Q13177	PAK2	T1117	S1110F	1110	Missense	distal	-7	no	22.105	24.523	EPSD	COSMIC	14.606	Up-regulation
STE_STE20_PAKA_PAK2_ST	Q04637	EIF4G1	Q13177	PAK2	T1117	S1110P	1110	Missense	distal	-7	no	22.105	22.403	EPSD	COSMIC	14.606	Up-regulation
STE_STE20_PAKA_PAK2_ST	Q04637	EIF4G1	Q13177	PAK2	T1117	T1117A	1117	Missense	central	0	yes	22.105	0.000	EPSD	COSMIC	14.606	Loss
STE_STE20_PAKA_PAK2_ST	Q04637	EIF4G1	Q13177	PAK2	T1117	R1114H	1114	Missense	distal	-3	no	22.105	7.262	EPSD	COSMIC;CCLE	14.606	Loss
STE_STE20_PAKA_PAK2_ST	Q04637	EIF4G1	Q13177	PAK2	T1117	S1118R	1118	Missense	proximal	1	no	22.105	17.724	EPSD	COSMIC	14.606	Down-regulation
STE_STE20_PAKA_PAK2_ST	Q04637	EIF4G1	Q13177	PAK2	T1117	R1122H	1122	Missense	distal	5	no	22.105	24.959	EPSD	COSMIC	14.606	Up-regulation
STE_STE20_PAKA_PAK2_ST	Q04637	EIF4G1	Q13177	PAK2	T1117	R1114S	1114	Missense	distal	-3	no	22.105	11.445	EPSD	COSMIC	14.606	Loss
STE_STE20_PAKA_PAK2_ST	Q04637	EIF4G1	Q13177	PAK2	T1119	A1116V	1116	Missense	distal	-3	no	14.783	-0.509	EPSD	COSMIC	14.606	Loss
STE_STE20_PAKA_PAK2_ST	Q04637	EIF4G1	Q13177	PAK2	T1119	T1117A	1117	Missense	proximal	-2	no	14.783	5.071	EPSD	COSMIC	14.606	Loss
STE_STE20_PAKA_PAK2_ST	Q04637	EIF4G1	Q13177	PAK2	T1119	R1114H	1114	Missense	distal	-5	no	14.783	15.133	EPSD	COSMIC;CCLE	14.606	Up-regulation
STE_STE20_PAKA_PAK2_ST	Q04637	EIF4G1	Q13177	PAK2	T1119	S1118R	1118	Missense	proximal	-1	no	14.783	15.637	EPSD	COSMIC	14.606	Up-regulation
STE_STE20_PAKA_PAK2_ST	Q04637	EIF4G1	Q13177	PAK2	T1119	A1125S	1125	Missense	distal	6	no	14.783	14.026	EPSD	COSMIC	14.606	Loss
STE_STE20_PAKA_PAK2_ST	Q04637	EIF4G1	Q13177	PAK2	T1119	R1122H	1122	Missense	distal	3	no	14.783	11.675	EPSD	COSMIC	14.606	Loss
STE_STE20_PAKA_PAK2_ST	Q04637	EIF4G1	Q13177	PAK2	T1119	R1114S	1114	Missense	distal	-5	no	14.783	16.852	EPSD	COSMIC	14.606	Up-regulation
STE_STE20_PAKA_PAK2_ST	Q04637	EIF4G1	Q13177	PAK2	S1124	T1117A	1117	Missense	distal	-7	no	21.620	21.703	EPSD	COSMIC	14.606	Up-regulation
STE_STE20_PAKA_PAK2_ST	Q04637	EIF4G1	Q13177	PAK2	S1124	S1118R	1118	Missense	distal	-6	no	21.620	25.672	EPSD	COSMIC	14.606	Up-regulation
STE_STE20_PAKA_PAK2_ST	Q04637	EIF4G1	Q13177	PAK2	S1124	A1125S	1125	Missense	proximal	1	no	21.620	23.657	EPSD	COSMIC	14.606	Up-regulation
STE_STE20_PAKA_PAK2_ST	Q04637	EIF4G1	Q13177	PAK2	S1124	R1122H	1122	Missense	proximal	-2	no	21.620	16.663	EPSD	COSMIC	14.606	Down-regulation
STE_STE20_PAKA_PAK2_ST	Q04637	EIF4G1	Q13177	PAK2	S1124	A1129V	1129	Missense	distal	5	no	21.620	20.780	EPSD	COSMIC	14.606	Down-regulation
STE_STE20_PAKA_PAK2_ST	Q04637	EIF4G1	Q13177	PAK2	T1132	R1139H	1139	Missense	distal	7	no	15.815	13.686	EPSD	COSMIC	14.606	Loss
STE_STE20_PAKA_PAK2_ST	Q04637	EIF4G1	Q13177	PAK2	T1132	A1125S	1125	Missense	distal	-7	no	15.815	15.575	EPSD	COSMIC	14.606	Down-regulation
STE_STE20_PAKA_PAK2_ST	Q04637	EIF4G1	Q13177	PAK2	T1132	A1129V	1129	Missense	distal	-3	no	15.815	0.523	EPSD	COSMIC	14.606	Loss
STE_STE20_PAKA_PAK2_ST	Q04637	EIF4G1	Q13177	PAK2	T1132	T1132P	1132	Missense	central	0	yes	15.815	0.000	EPSD	COSMIC	14.606	Loss
STE_STE20_PAKA_PAK2_ST	Q04637	EIF4G1	Q13177	PAK2	T1132	D1136Y	1136	Missense	distal	4	no	15.815	12.929	EPSD	COSMIC	14.606	Loss
STE_STE20_PAKA_PAK2_ST	Q04637	EIF4G1	Q13177	PAK2	S1134	D1136Y	1136	Missense	proximal	2	no	4.901	23.981	EPSD	COSMIC	14.606	Gain
STE_STE20_PAKA_PAK2_ST	Q04637	EIF4G1	Q13177	PAK2	S1145	R1150M	1150	Missense	distal	5	no	29.958	32.749	EPSD	COSMIC	14.606	Up-regulation
STE_STE20_PAKA_PAK2_ST	Q04637	EIF4G1	Q13177	PAK2	S1145	R1139H	1139	Missense	distal	-6	no	29.958	29.716	EPSD	COSMIC	14.606	Down-regulation
STE_STE20_PAKA_PAK2_ST	Q04637	EIF4G1	Q13177	PAK2	S1145	E1152K	1152	Missense	distal	7	no	29.958	27.253	EPSD	COSMIC	14.606	Down-regulation
STE_STE20_PAKA_PAK2_ST	Q04637	EIF4G1	Q13177	PAK2	S1145	E1149Q	1149	Missense	distal	4	no	29.958	30.670	EPSD	COSMIC	14.606	Up-regulation
STE_STE20_PAKA_PAK2_ST	Q04637	EIF4G1	Q13177	PAK2	S1145	R1143M	1143	Missense	proximal	-2	no	29.958	22.930	EPSD	COSMIC	14.606	Down-regulation
STE_STE20_PAKA_PAK2_ST	Q04637	EIF4G1	Q13177	PAK2	S1145	G1151D	1151	Missense	distal	6	no	29.958	29.623	EPSD	COSMIC	14.606	Down-regulation
STE_STE20_PAKA_PAK2_ST	Q04637	EIF4G1	Q13177	PAK2	S1145	R1148Q	1148	Missense	distal	3	no	29.958	28.144	EPSD	COSMIC	14.606	Down-regulation
STE_STE20_PAKA_PAK2_ST	Q04637	EIF4G1	Q13177	PAK2	S1164	R1166W	1166	Missense	proximal	2	no	10.974	18.045	EPSD	COSMIC	14.606	Gain
STE_STE20_PAKA_PAK2_ST	Q70Z35	PREX2	Q13177	PAK2	T374	E371K	371	Missense	distal	-3	no	8.689	27.703	EPSD	COSMIC	14.606	Gain
STE_STE20_PAKA_PAK2_ST	Q70Z35	PREX2	Q13177	PAK2	S1052	Q1046K	1046	Missense	distal	-6	no	15.309	16.920	EPSD	COSMIC	14.606	Up-regulation
STE_STE20_PAKA_PAK2_ST	Q70Z35	PREX2	Q13177	PAK2	S1052	S1052F	1052	Missense	central	0	yes	15.309	0.000	EPSD	COSMIC	14.606	Loss
STE_STE20_PAKA_PAK2_ST	Q70Z35	PREX2	Q13177	PAK2	S1052	S1057T	1057	Missense	distal	5	no	15.309	14.835	EPSD	COSMIC	14.606	Down-regulation
STE_STE20_PAKA_PAK2_ST	Q70Z35	PREX2	Q13177	PAK2	S1065	I1069M	1069	Missense	distal	4	no	23.060	19.578	EPSD	COSMIC	14.606	Down-regulation
STE_STE20_PAKA_PAK2_ST	Q70Z35	PREX2	Q13177	PAK2	S1065	D1072N	1072	Missense	distal	7	no	23.060	20.752	EPSD	COSMIC	14.606	Down-regulation
STE_STE20_PAKA_PAK2_ST	Q70Z35	PREX2	Q13177	PAK2	S1065	P1070T	1070	Missense	distal	5	no	23.060	24.132	EPSD	COSMIC	14.606	Up-regulation
STE_STE20_PAKA_PAK2_ST	Q70Z35	PREX2	Q13177	PAK2	S1107	S1113R	1113	Missense	distal	6	no	36.962	38.185	PhosphoSitePlus	COSMIC	14.606	Up-regulation
STE_STE20_PAKA_PAK2_ST	Q8IYU2	HACE1	Q13177	PAK2	S385	M379T	379	Missense	distal	-6	no	35.489	33.804	PhosphoSitePlus	COSMIC	14.606	Down-regulation
STE_STE20_PAKA_PAK2_ST	Q8IYU2	HACE1	Q13177	PAK2	S385	D384N	384	Missense	proximal	-1	no	35.489	29.080	PhosphoSitePlus	COSMIC	14.606	Down-regulation
CMGC_MAPK_ERK7_MAPK15_ST	Q8TD08	MAPK15	Q8TD08	MAPK15	T175	T180I	180	Missense	distal	5	no	10.983	11.124	EPSD;PhosphoSitePlus	COSMIC	5.395	Up-regulation
CMGC_MAPK_ERK7_MAPK15_ST	Q8TD08	MAPK15	Q8TD08	MAPK15	T175	E176D	176	Missense	proximal	1	no	10.983	10.067	EPSD;PhosphoSitePlus	COSMIC	5.395	Down-regulation
CMGC_MAPK_ERK7_MAPK15_ST	Q8TD08	MAPK15	Q8TD08	MAPK15	S192	E187D	187	Missense	distal	-5	no	10.763	10.256	EPSD;PhosphoSitePlus	COSMIC	5.395	Down-regulation
CMGC_MAPK_ERK7_MAPK15_ST	Q8TD08	MAPK15	Q8TD08	MAPK15	S331	R338C	338	Missense	distal	7	no	11.674	12.009	EPSD;PhosphoSitePlus	COSMIC	5.395	Up-regulation
CMGC_MAPK_ERK7_MAPK15_ST	Q8TD08	MAPK15	Q8TD08	MAPK15	S331	V328A	328	Missense	distal	-3	no	11.674	11.546	EPSD;PhosphoSitePlus	COSMIC;GDSC;CCLE	5.395	Down-regulation
CMGC_MAPK_ERK7_MAPK15_ST	Q8TD08	MAPK15	Q8TD08	MAPK15	T352	S353L	353	Missense	proximal	1	no	9.993	8.259	EPSD;PhosphoSitePlus	COSMIC	5.395	Down-regulation
CMGC_MAPK_ERK7_MAPK15_ST	Q8TD08	MAPK15	Q8TD08	MAPK15	T352	P358L	358	Missense	distal	6	no	9.993	10.196	EPSD;PhosphoSitePlus	COSMIC	5.395	Up-regulation
CMGC_MAPK_ERK7_MAPK15_ST	Q8TD08	MAPK15	Q8TD08	MAPK15	S362	P358L	358	Missense	distal	-4	no	9.448	9.502	EPSD;PhosphoSitePlus	COSMIC	5.395	Up-regulation
CMGC_MAPK_ERK7_MAPK15_ST	Q8TD08	MAPK15	Q8TD08	MAPK15	S379	G385D	385	Missense	distal	6	no	10.779	10.318	EPSD;PhosphoSitePlus	COSMIC	5.395	Down-regulation
CMGC_MAPK_ERK7_MAPK15_ST	Q8TD08	MAPK15	Q8TD08	MAPK15	S379	A373V	373	Missense	distal	-6	no	10.779	10.766	EPSD;PhosphoSitePlus	COSMIC	5.395	Down-regulation
CMGC_MAPK_ERK7_MAPK15_ST	Q8TD08	MAPK15	Q8TD08	MAPK15	S379	A373P	373	Missense	distal	-6	no	10.779	10.791	EPSD;PhosphoSitePlus	COSMIC	5.395	Up-regulation
CMGC_MAPK_ERK7_MAPK15_ST	Q8TD08	MAPK15	Q8TD08	MAPK15	S379	R372K	372	Missense	distal	-7	no	10.779	10.641	EPSD;PhosphoSitePlus	COSMIC	5.395	Down-regulation
CMGC_MAPK_ERK7_MAPK15_ST	Q8TD08	MAPK15	Q8TD08	MAPK15	S379	G385S	385	Missense	distal	6	no	10.779	9.869	EPSD;PhosphoSitePlus	COSMIC	5.395	Down-regulation
CMGC_MAPK_ERK7_MAPK15_ST	Q8TD08	MAPK15	Q8TD08	MAPK15	T381	G385D	385	Missense	distal	4	no	10.411	10.447	PhosphoSitePlus;EPSD	COSMIC	5.395	Up-regulation
CMGC_MAPK_ERK7_MAPK15_ST	Q8TD08	MAPK15	Q8TD08	MAPK15	T381	G385S	385	Missense	distal	4	no	10.411	10.768	PhosphoSitePlus;EPSD	COSMIC	5.395	Up-regulation
CMGC_MAPK_ERK7_MAPK15_ST	P25963	NFKBIA	Q8TD08	MAPK15	S32	M37K	37	Missense	distal	5	no	9.810	9.967	EPSD;PhosphoSitePlus	COSMIC	5.395	Up-regulation
CMGC_MAPK_ERK7_MAPK15_ST	P25963	NFKBIA	Q8TD08	MAPK15	S32	S36P	36	Missense	distal	4	no	9.810	9.517	EPSD;PhosphoSitePlus	COSMIC	5.395	Down-regulation
CMGC_MAPK_ERK7_MAPK15_ST	P25963	NFKBIA	Q8TD08	MAPK15	S32	S32N	32	Missense	central	0	yes	9.810	0.000	EPSD;PhosphoSitePlus	COSMIC	5.395	Loss
CMGC_MAPK_ERK7_MAPK15_ST	P25963	NFKBIA	Q8TD08	MAPK15	S36	M37K	37	Missense	proximal	1	no	10.289	10.236	PhosphoSitePlus;EPSD	COSMIC	5.395	Down-regulation
CMGC_MAPK_ERK7_MAPK15_ST	P25963	NFKBIA	Q8TD08	MAPK15	S36	E40D	40	Missense	distal	4	no	10.289	10.128	PhosphoSitePlus;EPSD	COSMIC	5.395	Down-regulation
CMGC_MAPK_ERK7_MAPK15_ST	P25963	NFKBIA	Q8TD08	MAPK15	S36	E43K	43	Missense	distal	7	no	10.289	10.924	PhosphoSitePlus;EPSD	COSMIC	5.395	Up-regulation
CMGC_MAPK_ERK7_MAPK15_ST	P25963	NFKBIA	Q8TD08	MAPK15	S36	S36P	36	Missense	central	0	yes	10.289	0.000	PhosphoSitePlus;EPSD	COSMIC	5.395	Loss
CMGC_MAPK_ERK7_MAPK15_ST	P25963	NFKBIA	Q8TD08	MAPK15	S36	E43Q	43	Missense	distal	7	no	10.289	10.575	PhosphoSitePlus;EPSD	COSMIC	5.395	Up-regulation
CMGC_MAPK_ERK7_MAPK15_ST	P25963	NFKBIA	Q8TD08	MAPK15	S36	S32N	32	Missense	distal	-4	no	10.289	10.337	PhosphoSitePlus;EPSD	COSMIC	5.395	Up-regulation
CMGC_MAPK_ERK7_MAPK15_ST	P25963	NFKBIA	Q8TD08	MAPK15	S283	E284D	284	Missense	proximal	1	no	5.408	4.492	EPSD	COSMIC	5.395	Loss
CMGC_MAPK_ERK7_MAPK15_ST	P25963	NFKBIA	Q8TD08	MAPK15	S283	E287V	287	Missense	distal	4	no	5.408	5.124	EPSD	COSMIC	5.395	Loss
CMGC_MAPK_ERK7_MAPK15_ST	P25963	NFKBIA	Q8TD08	MAPK15	S283	Y289C	289	Missense	distal	6	no	5.408	5.383	EPSD	COSMIC	5.395	Loss
CMGC_MAPK_ERK7_MAPK15_ST	P25963	NFKBIA	Q8TD08	MAPK15	S283	N276K	276	Missense	distal	-7	no	5.408	5.441	EPSD	COSMIC	5.395	Up-regulation
CMGC_MAPK_ERK7_MAPK15_ST	P05412	JUN	Q8TD08	MAPK15	T62	K56N	56	Missense	distal	-6	no	6.477	6.521	EPSD	COSMIC	5.395	Up-regulation
CMGC_MAPK_ERK7_MAPK15_ST	P05412	JUN	Q8TD08	MAPK15	T62	L61F	61	Missense	proximal	-1	no	6.477	6.365	EPSD	COSMIC	5.395	Down-regulation
CMGC_MAPK_ERK7_MAPK15_ST	P05412	JUN	Q8TD08	MAPK15	S63	K56N	56	Missense	distal	-7	no	11.097	11.064	EPSD;PhosphoSitePlus	COSMIC	5.395	Down-regulation
CMGC_MAPK_ERK7_MAPK15_ST	P05412	JUN	Q8TD08	MAPK15	S63	L61F	61	Missense	proximal	-2	no	11.097	11.067	EPSD;PhosphoSitePlus	COSMIC	5.395	Down-regulation
CMGC_MAPK_ERK7_MAPK15_ST	P05412	JUN	Q8TD08	MAPK15	S73	R78H	78	Missense	distal	5	no	11.823	12.003	PhosphoSitePlus;EPSD	COSMIC	5.395	Up-regulation
CMGC_MAPK_ERK7_MAPK15_ST	P05412	JUN	Q8TD08	MAPK15	T89	P92Q	92	Missense	distal	3	no	5.426	5.417	EPSD	COSMIC	5.395	Down-regulation
CMGC_MAPK_ERK7_MAPK15_ST	P05412	JUN	Q8TD08	MAPK15	T89	P94S	94	Missense	distal	5	no	5.426	5.005	EPSD	COSMIC	5.395	Loss
TK_Ret_RET_Y	P27986	PIK3R1	P07949	RET	Y203	Y203C	203	Missense	central	0	yes	52.559	0.000	PhosphoSitePlus	COSMIC	28.094	Loss
TK_Ret_RET_Y	P27986	PIK3R1	P07949	RET	Y203	L209F	209	Missense	distal	6	no	52.559	52.142	PhosphoSitePlus	COSMIC	28.094	Down-regulation
TK_Ret_RET_Y	P27986	PIK3R1	P07949	RET	Y203	E205K	205	Missense	proximal	2	no	52.559	52.625	PhosphoSitePlus	COSMIC	28.094	Up-regulation
TK_Ret_RET_Y	P27986	PIK3R1	P07949	RET	Y203	A210D	210	Missense	distal	7	no	52.559	47.564	PhosphoSitePlus	COSMIC	28.094	Down-regulation
TK_Ret_RET_Y	P27986	PIK3R1	P07949	RET	Y368	G375R	375	Missense	distal	7	no	21.838	29.560	EPSD	COSMIC	28.094	Gain
TK_Ret_RET_Y	P07949	RET	P07949	RET	Y687	A682V	682	Missense	distal	-5	no	50.930	50.923	EPSD;PhosphoSitePlus	COSMIC	28.094	Down-regulation
TK_Ret_RET_Y	P07949	RET	P07949	RET	Y687	Q681H	681	Missense	distal	-6	no	50.930	50.944	EPSD;PhosphoSitePlus	COSMIC	28.094	Up-regulation
TK_Ret_RET_Y	P07949	RET	P07949	RET	Y687	P684L	684	Missense	distal	-3	no	50.930	49.740	EPSD;PhosphoSitePlus	COSMIC	28.094	Down-regulation
TK_Ret_RET_Y	P07949	RET	P07949	RET	Y687	S690F	690	Missense	distal	3	no	50.930	49.223	EPSD;PhosphoSitePlus	COSMIC	28.094	Down-regulation
TK_Ret_RET_Y	P07949	RET	P07949	RET	Y687	P684S	684	Missense	distal	-3	no	50.930	51.606	EPSD;PhosphoSitePlus	COSMIC	28.094	Up-regulation
TK_Ret_RET_Y	P07949	RET	P07949	RET	Y791	I788V	788	Missense	distal	-3	no	26.069	28.674	EPSD	COSMIC	28.094	Gain
TK_Ret_RET_Y	P07949	RET	P07949	RET	Y806	A807P	807	Missense	proximal	1	no	31.198	30.343	EPSD;PhosphoSitePlus	COSMIC	28.094	Down-regulation
TK_Ret_RET_Y	P07949	RET	P07949	RET	Y806	P799L	799	Missense	distal	-7	no	31.198	27.616	EPSD;PhosphoSitePlus	COSMIC	28.094	Loss
TK_Ret_RET_Y	P07949	RET	P07949	RET	Y806	V804M	804	Missense	proximal	-2	no	31.198	29.780	EPSD;PhosphoSitePlus	COSMIC;GDSC	28.094	Down-regulation
TK_Ret_RET_Y	P07949	RET	P07949	RET	Y806	K808E	808	Missense	proximal	2	no	31.198	31.132	EPSD;PhosphoSitePlus	COSMIC	28.094	Down-regulation
TK_Ret_RET_Y	P07949	RET	P07949	RET	Y809	A807P	807	Missense	proximal	-2	no	39.481	40.026	EPSD;PhosphoSitePlus	COSMIC	28.094	Up-regulation
TK_Ret_RET_Y	P07949	RET	P07949	RET	Y809	L816P	816	Missense	distal	7	no	39.481	43.338	EPSD;PhosphoSitePlus	COSMIC	28.094	Up-regulation
TK_Ret_RET_Y	P07949	RET	P07949	RET	Y809	V804M	804	Missense	distal	-5	no	39.481	39.317	EPSD;PhosphoSitePlus	COSMIC;GDSC	28.094	Down-regulation
TK_Ret_RET_Y	P07949	RET	P07949	RET	Y809	K808E	808	Missense	proximal	-1	no	39.481	39.473	EPSD;PhosphoSitePlus	COSMIC	28.094	Down-regulation
TK_Ret_RET_Y	P07949	RET	P07949	RET	Y826	R833C	833	Missense	distal	7	no	41.269	32.915	PhosphoSitePlus;EPSD	COSMIC	28.094	Down-regulation
TK_Ret_RET_Y	P07949	RET	P07949	RET	Y826	G828A	828	Missense	proximal	2	no	41.269	41.610	PhosphoSitePlus;EPSD	COSMIC	28.094	Up-regulation
TK_Ret_RET_Y	P07949	RET	P07949	RET	Y826	R820S	820	Missense	distal	-6	no	41.269	41.297	PhosphoSitePlus;EPSD	COSMIC	28.094	Up-regulation
TK_Ret_RET_Y	P07949	RET	P07949	RET	Y826	Y826F	826	Missense	central	0	yes	41.269	0.000	PhosphoSitePlus;EPSD	COSMIC	28.094	Loss
TK_Ret_RET_Y	P07949	RET	P07949	RET	Y826	R833H	833	Missense	distal	7	no	41.269	33.161	PhosphoSitePlus;EPSD	COSMIC	28.094	Down-regulation
TK_Ret_RET_Y	P07949	RET	P07949	RET	Y826	G830A	830	Missense	distal	4	no	41.269	43.136	PhosphoSitePlus;EPSD	COSMIC	28.094	Up-regulation
TK_Ret_RET_Y	P07949	RET	P07949	RET	Y826	R820L	820	Missense	distal	-6	no	41.269	41.267	PhosphoSitePlus;EPSD	COSMIC	28.094	Down-regulation
TK_Ret_RET_Y	P07949	RET	P07949	RET	Y826	K821E	821	Missense	distal	-5	no	41.269	41.139	PhosphoSitePlus;EPSD	COSMIC	28.094	Down-regulation
TK_Ret_RET_Y	P07949	RET	P07949	RET	Y900	D903N	903	Missense	distal	3	no	36.527	36.024	EPSD;PhosphoSitePlus	COSMIC	28.094	Down-regulation
TK_Ret_RET_Y	P07949	RET	P07949	RET	Y900	V899I	899	Missense	proximal	-1	no	36.527	36.718	EPSD;PhosphoSitePlus	COSMIC	28.094	Up-regulation
TK_Ret_RET_Y	P07949	RET	P07949	RET	Y900	S904P	904	Missense	distal	4	no	36.527	37.024	EPSD;PhosphoSitePlus	COSMIC	28.094	Up-regulation
TK_Ret_RET_Y	P07949	RET	P07949	RET	Y900	V906M	906	Missense	distal	6	no	36.527	36.707	EPSD;PhosphoSitePlus	COSMIC	28.094	Up-regulation
TK_Ret_RET_Y	P07949	RET	P07949	RET	Y900	R897Q	897	Missense	distal	-3	no	36.527	35.603	EPSD;PhosphoSitePlus	COSMIC	28.094	Down-regulation
TK_Ret_RET_Y	P07949	RET	P07949	RET	Y900	E902K	902	Missense	proximal	2	no	36.527	36.593	EPSD;PhosphoSitePlus	COSMIC	28.094	Up-regulation
TK_Ret_RET_Y	P07949	RET	P07949	RET	Y900	R897P	897	Missense	distal	-3	no	36.527	37.396	EPSD;PhosphoSitePlus	COSMIC	28.094	Up-regulation
TK_Ret_RET_Y	P07949	RET	P07949	RET	Y900	Y905D	905	Missense	distal	5	no	36.527	36.861	EPSD;PhosphoSitePlus	COSMIC	28.094	Up-regulation
TK_Ret_RET_Y	P07949	RET	P07949	RET	Y900	L895S	895	Missense	distal	-5	no	36.527	37.169	EPSD;PhosphoSitePlus	COSMIC	28.094	Up-regulation
TK_Ret_RET_Y	P07949	RET	P07949	RET	Y900	S904F	904	Missense	distal	4	no	36.527	33.262	EPSD;PhosphoSitePlus	COSMIC	28.094	Down-regulation
TK_Ret_RET_Y	P07949	RET	P07949	RET	Y900	S904L	904	Missense	distal	4	no	36.527	35.178	EPSD;PhosphoSitePlus	COSMIC	28.094	Down-regulation
TK_Ret_RET_Y	P07949	RET	P07949	RET	Y900	L895W	895	Missense	distal	-5	no	36.527	36.024	EPSD;PhosphoSitePlus	COSMIC	28.094	Down-regulation
TK_Ret_RET_Y	P07949	RET	P07949	RET	Y905	D903N	903	Missense	proximal	-2	no	53.485	51.121	EPSD;PhosphoSitePlus	COSMIC	28.094	Down-regulation
TK_Ret_RET_Y	P07949	RET	P07949	RET	Y905	V899I	899	Missense	distal	-6	no	53.485	53.442	EPSD;PhosphoSitePlus	COSMIC	28.094	Down-regulation
TK_Ret_RET_Y	P07949	RET	P07949	RET	Y905	S904P	904	Missense	proximal	-1	no	53.485	53.579	EPSD;PhosphoSitePlus	COSMIC	28.094	Up-regulation
TK_Ret_RET_Y	P07949	RET	P07949	RET	Y905	G911D	911	Missense	distal	6	no	53.485	53.543	EPSD;PhosphoSitePlus	COSMIC	28.094	Up-regulation
TK_Ret_RET_Y	P07949	RET	P07949	RET	Y905	V906M	906	Missense	proximal	1	no	53.485	53.112	EPSD;PhosphoSitePlus	COSMIC	28.094	Down-regulation
TK_Ret_RET_Y	P07949	RET	P07949	RET	Y905	E902K	902	Missense	distal	-3	no	53.485	53.522	EPSD;PhosphoSitePlus	COSMIC	28.094	Up-regulation
TK_Ret_RET_Y	P07949	RET	P07949	RET	Y905	Y905D	905	Missense	central	0	yes	53.485	0.000	EPSD;PhosphoSitePlus	COSMIC	28.094	Loss
TK_Ret_RET_Y	P07949	RET	P07949	RET	Y905	S904F	904	Missense	proximal	-1	no	53.485	53.703	EPSD;PhosphoSitePlus	COSMIC	28.094	Up-regulation
TK_Ret_RET_Y	P07949	RET	P07949	RET	Y905	S904L	904	Missense	proximal	-1	no	53.485	53.591	EPSD;PhosphoSitePlus	COSMIC	28.094	Up-regulation
TK_Ret_RET_Y	P07949	RET	P07949	RET	Y905	R908K	908	Missense	distal	3	no	53.485	52.953	EPSD;PhosphoSitePlus	COSMIC	28.094	Down-regulation
TK_Ret_RET_Y	P07949	RET	P07949	RET	Y981	R982C	982	Missense	proximal	1	no	39.068	38.486	EPSD;PhosphoSitePlus	COSMIC	28.094	Down-regulation
TK_Ret_RET_Y	P07949	RET	P07949	RET	Y981	R982S	982	Missense	proximal	1	no	39.068	40.831	EPSD;PhosphoSitePlus	COSMIC	28.094	Up-regulation
TK_Ret_RET_Y	P07949	RET	P07949	RET	Y981	S977I	977	Missense	distal	-4	no	39.068	27.874	EPSD;PhosphoSitePlus	COSMIC	28.094	Loss
TK_Ret_RET_Y	P07949	RET	P07949	RET	Y981	E978Q	978	Missense	distal	-3	no	39.068	37.128	EPSD;PhosphoSitePlus	COSMIC	28.094	Down-regulation
TK_Ret_RET_Y	P07949	RET	P07949	RET	Y981	S977R	977	Missense	distal	-4	no	39.068	32.453	EPSD;PhosphoSitePlus	COSMIC	28.094	Down-regulation
TK_Ret_RET_Y	P07949	RET	P07949	RET	Y981	M980T	980	Missense	proximal	-1	no	39.068	39.149	EPSD;PhosphoSitePlus	COSMIC;GDSC	28.094	Up-regulation
TK_Ret_RET_Y	P07949	RET	P07949	RET	Y1015	M1009I	1009	Missense	distal	-6	no	48.606	48.551	EPSD;PhosphoSitePlus	COSMIC	28.094	Down-regulation
TK_Ret_RET_Y	P07949	RET	P07949	RET	Y1015	M1009K	1009	Missense	distal	-6	no	48.606	48.602	EPSD;PhosphoSitePlus	COSMIC	28.094	Down-regulation
TK_Ret_RET_Y	P07949	RET	P07949	RET	Y1015	R1013K	1013	Missense	proximal	-2	no	48.606	46.450	EPSD;PhosphoSitePlus	COSMIC	28.094	Down-regulation
TK_Ret_RET_Y	P07949	RET	P07949	RET	Y1015	M1009T	1009	Missense	distal	-6	no	48.606	48.585	EPSD;PhosphoSitePlus	COSMIC	28.094	Down-regulation
TK_Ret_RET_Y	P07949	RET	P07949	RET	Y1015	R1013T	1013	Missense	proximal	-2	no	48.606	47.820	EPSD;PhosphoSitePlus	COSMIC	28.094	Down-regulation
TK_Ret_RET_Y	P07949	RET	P07949	RET	Y1015	K1011E	1011	Missense	distal	-4	no	48.606	49.275	EPSD;PhosphoSitePlus	COSMIC	28.094	Up-regulation
TK_Ret_RET_Y	P07949	RET	P07949	RET	Y1015	T1022A	1022	Missense	distal	7	no	48.606	48.813	EPSD;PhosphoSitePlus	COSMIC	28.094	Up-regulation
TK_Ret_RET_Y	P07949	RET	P07949	RET	Y1015	M1008T	1008	Missense	distal	-7	no	48.606	52.701	EPSD;PhosphoSitePlus	COSMIC	28.094	Up-regulation
TK_Ret_RET_Y	P07949	RET	P07949	RET	Y1029	S1026F	1026	Missense	distal	-3	no	38.638	35.808	EPSD;PhosphoSitePlus	COSMIC	28.094	Down-regulation
TK_Ret_RET_Y	P07949	RET	P07949	RET	Y1029	T1022A	1022	Missense	distal	-7	no	38.638	37.510	EPSD;PhosphoSitePlus	COSMIC	28.094	Down-regulation
TK_Ret_RET_Y	P07949	RET	P07949	RET	Y1029	E1036Q	1036	Missense	distal	7	no	38.638	34.120	EPSD;PhosphoSitePlus	COSMIC	28.094	Down-regulation
TK_Ret_RET_Y	P07949	RET	P07949	RET	Y1029	D1031Y	1031	Missense	proximal	2	no	38.638	37.730	EPSD;PhosphoSitePlus	COSMIC	28.094	Down-regulation
TK_Ret_RET_Y	P07949	RET	P07949	RET	Y1029	S1024F	1024	Missense	distal	-5	no	38.638	36.934	EPSD;PhosphoSitePlus	COSMIC	28.094	Down-regulation
TK_Ret_RET_Y	P07949	RET	P07949	RET	Y1062	T1055A	1055	Missense	distal	-7	no	59.960	58.832	EPSD;PhosphoSitePlus	COSMIC	28.094	Down-regulation
TK_Ret_RET_Y	P07949	RET	P07949	RET	Y1062	K1060R	1060	Missense	proximal	-2	no	59.960	62.115	EPSD;PhosphoSitePlus	COSMIC	28.094	Up-regulation
TK_Ret_RET_Y	P07949	RET	P07949	RET	Y1062	E1058K	1058	Missense	distal	-4	no	59.960	59.291	EPSD;PhosphoSitePlus	COSMIC	28.094	Down-regulation
TK_Ret_RET_Y	P07949	RET	P07949	RET	Y1062	G1063C	1063	Missense	proximal	1	no	59.960	60.129	EPSD;PhosphoSitePlus	COSMIC	28.094	Up-regulation
TK_Ret_RET_Y	P07949	RET	P07949	RET	Y1062	N1068S	1068	Missense	distal	6	no	59.960	60.448	EPSD;PhosphoSitePlus	COSMIC	28.094	Up-regulation
TK_Ret_RET_Y	P07949	RET	P07949	RET	Y1062	M1064L	1064	Missense	proximal	2	no	59.960	59.722	EPSD;PhosphoSitePlus	COSMIC	28.094	Down-regulation
TK_Ret_RET_Y	P07949	RET	P07949	RET	Y1062	P1067L	1067	Missense	distal	5	no	59.960	59.467	EPSD;PhosphoSitePlus	COSMIC	28.094	Down-regulation
TK_Ret_RET_Y	P07949	RET	P07949	RET	Y1062	G1063D	1063	Missense	proximal	1	no	59.960	62.089	EPSD;PhosphoSitePlus	COSMIC	28.094	Up-regulation
TK_Ret_RET_Y	P07949	RET	P07949	RET	Y1090	T1085A	1085	Missense	distal	-5	no	37.417	38.286	EPSD;PhosphoSitePlus	COSMIC	28.094	Up-regulation
TK_Ret_RET_Y	P07949	RET	P07949	RET	Y1090	T1085S	1085	Missense	distal	-5	no	37.417	38.492	EPSD;PhosphoSitePlus	COSMIC	28.094	Up-regulation
TK_Ret_RET_Y	P07949	RET	P07949	RET	Y1090	P1088L	1088	Missense	proximal	-2	no	37.417	33.584	EPSD;PhosphoSitePlus	COSMIC	28.094	Down-regulation
TK_Ret_RET_Y	P07949	RET	P07949	RET	Y1090	S1094R	1094	Missense	distal	4	no	37.417	37.565	EPSD;PhosphoSitePlus	COSMIC	28.094	Up-regulation
TK_Ret_RET_Y	P07949	RET	P07949	RET	Y1090	V1095L	1095	Missense	distal	5	no	37.417	37.170	EPSD;PhosphoSitePlus	COSMIC	28.094	Down-regulation
TK_Ret_RET_Y	P07949	RET	P07949	RET	Y1090	S1094G	1094	Missense	distal	4	no	37.417	35.876	EPSD;PhosphoSitePlus	COSMIC	28.094	Down-regulation
TK_Ret_RET_Y	P07949	RET	P07949	RET	Y1096	S1094R	1094	Missense	proximal	-2	no	59.110	59.697	EPSD;PhosphoSitePlus	COSMIC	28.094	Up-regulation
TK_Ret_RET_Y	P07949	RET	P07949	RET	Y1096	V1095L	1095	Missense	proximal	-1	no	59.110	59.207	EPSD;PhosphoSitePlus	COSMIC	28.094	Up-regulation
TK_Ret_RET_Y	P07949	RET	P07949	RET	Y1096	W1099Y	1099	Missense	distal	3	no	59.110	58.889	EPSD;PhosphoSitePlus	COSMIC	28.094	Down-regulation
TK_Ret_RET_Y	P07949	RET	P07949	RET	Y1096	S1094G	1094	Missense	proximal	-2	no	59.110	55.418	EPSD;PhosphoSitePlus	COSMIC	28.094	Down-regulation
TK_Ret_RET_Y	O15530	PDPK1	P07949	RET	Y9	V12M	12	Missense	distal	3	no	35.274	34.975	PhosphoSitePlus	COSMIC	28.094	Down-regulation
TK_Ret_RET_Y	O15530	PDPK1	P07949	RET	Y9	R3G	3	Missense	distal	-6	no	35.274	35.230	PhosphoSitePlus	COSMIC	28.094	Down-regulation
TK_Ret_RET_Y	O15530	PDPK1	P07949	RET	Y248	Y248H	248	Missense	central	0	yes	37.834	0.000	EPSD	COSMIC	28.094	Loss
TK_Ret_RET_Y	O15530	PDPK1	P07949	RET	Y373	N378I	378	Missense	distal	5	no	29.217	28.869	EPSD	COSMIC	28.094	Down-regulation
TK_Ret_RET_Y	O15530	PDPK1	P07949	RET	Y415	D418N	418	Missense	distal	3	no	37.150	36.646	EPSD	COSMIC	28.094	Down-regulation
TK_Ret_RET_Y	Q99704	DOK1	P07949	RET	Y315	D320N	320	Missense	distal	5	no	32.697	32.748	EPSD	COSMIC	28.094	Up-regulation
TK_Ret_RET_Y	Q99704	DOK1	P07949	RET	Y398	V393L	393	Missense	distal	-5	no	52.200	51.771	PhosphoSitePlus	COSMIC	28.094	Down-regulation
TK_Ret_RET_Y	Q99704	DOK1	P07949	RET	Y409	P414S	414	Missense	distal	5	no	29.158	29.229	EPSD	COSMIC	28.094	Up-regulation
TK_Ret_RET_Y	Q99704	DOK1	P07949	RET	Y409	R415Q	415	Missense	distal	6	no	29.158	28.783	EPSD	COSMIC	28.094	Down-regulation
TK_Ret_RET_Y	Q99704	DOK1	P07949	RET	Y409	A410D	410	Missense	proximal	1	no	29.158	29.268	EPSD	COSMIC	28.094	Up-regulation
TK_Ret_RET_Y	Q99704	DOK1	P07949	RET	Y409	A410T	410	Missense	proximal	1	no	29.158	27.724	EPSD	COSMIC	28.094	Loss
TK_Ret_RET_Y	Q99704	DOK1	P07949	RET	Y409	P413L	413	Missense	distal	4	no	29.158	27.313	EPSD	COSMIC	28.094	Loss
TK_Ret_RET_Y	Q99704	DOK1	P07949	RET	Y409	R415W	415	Missense	distal	6	no	29.158	28.761	EPSD	COSMIC	28.094	Down-regulation
TK_Ret_RET_Y	Q99704	DOK1	P07949	RET	Y409	V411M	411	Missense	proximal	2	no	29.158	28.954	EPSD	COSMIC	28.094	Down-regulation
TK_Ret_RET_Y	Q99704	DOK1	P07949	RET	Y449	H444D	444	Missense	distal	-5	no	35.175	35.935	EPSD	COSMIC	28.094	Up-regulation
TK_Ret_RET_Y	Q99704	DOK1	P07949	RET	Y449	A447V	447	Missense	proximal	-2	no	35.175	33.908	EPSD	COSMIC	28.094	Down-regulation
TK_Ret_RET_Y	Q05397	PTK2	P07949	RET	Y576	R569L	569	Missense	distal	-7	no	43.100	39.471	EPSD;PhosphoSitePlus	COSMIC	28.094	Down-regulation
TK_Ret_RET_Y	Q05397	PTK2	P07949	RET	Y576	A579V	579	Missense	distal	3	no	43.100	43.482	EPSD;PhosphoSitePlus	COSMIC	28.094	Up-regulation
TK_Ret_RET_Y	Q05397	PTK2	P07949	RET	Y577	A579V	579	Missense	proximal	2	no	45.218	45.339	EPSD;PhosphoSitePlus	COSMIC	28.094	Up-regulation
TK_Ret_RET_Y	Q05397	PTK2	P07949	RET	Y861	D868N	868	Missense	distal	7	no	43.327	41.974	EPSD;PhosphoSitePlus	COSMIC	28.094	Down-regulation
TK_Ret_RET_Y	Q05397	PTK2	P07949	RET	Y861	G865C	865	Missense	distal	4	no	43.327	42.856	EPSD;PhosphoSitePlus	COSMIC	28.094	Down-regulation
TK_Ret_RET_Y	Q05397	PTK2	P07949	RET	Y898	E900V	900	Missense	proximal	2	no	32.715	32.795	EPSD	COSMIC	28.094	Up-regulation
TK_Ret_RET_Y	Q05397	PTK2	P07949	RET	Y925	G930C	930	Missense	distal	5	no	45.626	45.619	PhosphoSitePlus;EPSD	COSMIC	28.094	Down-regulation
TK_Ret_RET_Y	Q05397	PTK2	P07949	RET	Y925	D918G	918	Missense	distal	-7	no	45.626	41.803	PhosphoSitePlus;EPSD	COSMIC	28.094	Down-regulation
TK_Ret_RET_Y	Q05397	PTK2	P07949	RET	Y925	E926K	926	Missense	proximal	1	no	45.626	45.547	PhosphoSitePlus;EPSD	COSMIC	28.094	Down-regulation
TK_Ret_RET_Y	Q05397	PTK2	P07949	RET	Y925	Y925C	925	Missense	central	0	yes	45.626	0.000	PhosphoSitePlus;EPSD	COSMIC	28.094	Loss
TK_Ret_RET_Y	Q05397	PTK2	P07949	RET	Y925	R919L	919	Missense	distal	-6	no	45.626	45.625	PhosphoSitePlus;EPSD	COSMIC	28.094	Down-regulation
TK_Ret_RET_Y	Q05397	PTK2	P07949	RET	Y925	R919Q	919	Missense	distal	-6	no	45.626	45.583	PhosphoSitePlus;EPSD	COSMIC	28.094	Down-regulation
TK_Ret_RET_Y	Q05397	PTK2	P07949	RET	Y1016	Q1019H	1019	Missense	distal	3	no	34.089	34.387	EPSD	COSMIC	28.094	Up-regulation
TK_Ret_RET_Y	Q05397	PTK2	P07949	RET	Y1016	M1020T	1020	Missense	distal	4	no	34.089	34.063	EPSD	COSMIC	28.094	Down-regulation
TK_Ret_RET_Y	Q05397	PTK2	P07949	RET	Y1016	A1023T	1023	Missense	distal	7	no	34.089	33.881	EPSD	COSMIC	28.094	Down-regulation
TK_Ret_RET_Y	P19174	PLCG1	P07949	RET	Y93	F99L	99	Missense	distal	6	no	30.815	31.232	EPSD	COSMIC	28.094	Up-regulation
TK_Ret_RET_Y	P19174	PLCG1	P07949	RET	Y93	R88W	88	Missense	distal	-5	no	30.815	30.385	EPSD	COSMIC	28.094	Down-regulation
TK_Ret_RET_Y	P19174	PLCG1	P07949	RET	Y506	P507S	507	Missense	proximal	1	no	28.381	29.730	EPSD	COSMIC	28.094	Up-regulation
TK_Ret_RET_Y	P19174	PLCG1	P07949	RET	Y506	Y509H	509	Missense	distal	3	no	28.381	28.626	EPSD	COSMIC	28.094	Up-regulation
TK_Ret_RET_Y	P19174	PLCG1	P07949	RET	Y506	H508Q	508	Missense	proximal	2	no	28.381	28.268	EPSD	COSMIC	28.094	Down-regulation
TK_Ret_RET_Y	P19174	PLCG1	P07949	RET	Y506	H508R	508	Missense	proximal	2	no	28.381	28.833	EPSD	COSMIC	28.094	Up-regulation
TK_Ret_RET_Y	P19174	PLCG1	P07949	RET	Y669	W668G	668	Missense	proximal	-1	no	39.231	39.253	EPSD	COSMIC	28.094	Up-regulation
TK_Ret_RET_Y	P19174	PLCG1	P07949	RET	Y669	A671S	671	Missense	proximal	2	no	39.231	39.501	EPSD	COSMIC	28.094	Up-regulation
TK_Ret_RET_Y	P19174	PLCG1	P07949	RET	Y669	A662G	662	Missense	distal	-7	no	39.231	34.770	EPSD	COSMIC	28.094	Down-regulation
TK_Ret_RET_Y	P19174	PLCG1	P07949	RET	Y669	S665I	665	Missense	distal	-4	no	39.231	28.037	EPSD	COSMIC	28.094	Loss
TK_Ret_RET_Y	P19174	PLCG1	P07949	RET	Y669	A662T	662	Missense	distal	-7	no	39.231	40.359	EPSD	COSMIC;GDSC;CCLE	28.094	Up-regulation
TK_Ret_RET_Y	P19174	PLCG1	P07949	RET	Y771	Y775F	775	Missense	distal	4	no	29.084	28.322	EPSD	COSMIC	28.094	Down-regulation
TK_Ret_RET_Y	Q8N4X5	AFAP1L2	P07949	RET	Y54	S47I	47	Missense	distal	-7	no	39.951	35.313	PhosphoSitePlus	COSMIC;CCLE	28.094	Down-regulation
TK_Ret_RET_Y	Q8N4X5	AFAP1L2	P07949	RET	Y124	E118D	118	Missense	distal	-6	no	30.292	30.287	EPSD	COSMIC	28.094	Down-regulation
TK_Ret_RET_Y	Q8N4X5	AFAP1L2	P07949	RET	Y413	P407R	407	Missense	distal	-6	no	30.679	30.671	EPSD	COSMIC;GDSC;CCLE	28.094	Down-regulation
TK_Ret_RET_Y	Q8N4X5	AFAP1L2	P07949	RET	Y413	K420N	420	Missense	distal	7	no	30.679	28.256	EPSD	COSMIC	28.094	Down-regulation
TK_Ret_RET_Y	Q8N4X5	AFAP1L2	P07949	RET	Y457	A462S	462	Missense	distal	5	no	38.835	38.880	EPSD	COSMIC	28.094	Up-regulation
TK_Ret_RET_Y	Q8N4X5	AFAP1L2	P07949	RET	Y457	D458G	458	Missense	proximal	1	no	38.835	36.706	EPSD	COSMIC	28.094	Down-regulation
TK_Ret_RET_Y	Q8N4X5	AFAP1L2	P07949	RET	Y537	E530K	530	Missense	distal	-7	no	36.315	35.404	EPSD	COSMIC	28.094	Down-regulation
TK_Ret_RET_Y	Q8N4X5	AFAP1L2	P07949	RET	Y668	T661S	661	Missense	distal	-7	no	34.635	32.805	EPSD	COSMIC	28.094	Down-regulation
TK_Ret_RET_Y	P45984	MAPK9	P07949	RET	Y185	R189W	189	Missense	distal	4	no	56.127	54.198	PhosphoSitePlus	COSMIC	28.094	Down-regulation
TK_Ret_RET_Y	P45984	MAPK9	P07949	RET	Y185	R192Q	192	Missense	distal	7	no	56.127	45.857	PhosphoSitePlus	COSMIC	28.094	Down-regulation
TK_Ret_RET_Y	P45984	MAPK9	P07949	RET	Y185	R189Q	189	Missense	distal	4	no	56.127	53.160	PhosphoSitePlus	COSMIC	28.094	Down-regulation
TK_Ret_RET_Y	P31749	AKT1	P07949	RET	Y315	E322Q	322	Missense	distal	7	no	39.688	35.170	PhosphoSitePlus	COSMIC	28.094	Down-regulation
TK_Ret_RET_Y	P31749	AKT1	P07949	RET	Y315	T312I	312	Missense	distal	-3	no	39.688	38.352	PhosphoSitePlus	COSMIC	28.094	Down-regulation
TK_Ret_RET_Y	P31749	AKT1	P07949	RET	Y315	V320L	320	Missense	distal	5	no	39.688	39.441	PhosphoSitePlus	COSMIC	28.094	Down-regulation
TK_Ret_RET_Y	P28482	MAPK1	P07949	RET	Y25	P23S	23	Missense	proximal	-2	no	29.557	28.633	EPSD	COSMIC	28.094	Down-regulation
TK_Ret_RET_Y	P28482	MAPK1	P07949	RET	Y25	I31M	31	Missense	distal	6	no	29.557	30.805	EPSD	COSMIC	28.094	Up-regulation
TK_Ret_RET_Y	P28482	MAPK1	P07949	RET	Y36	E33Q	33	Missense	distal	-3	no	32.135	30.196	EPSD	COSMIC	28.094	Down-regulation
TK_Ret_RET_Y	P28482	MAPK1	P07949	RET	Y36	G34D	34	Missense	proximal	-2	no	32.135	36.189	EPSD	COSMIC	28.094	Up-regulation
TK_Ret_RET_Y	P28482	MAPK1	P07949	RET	Y36	I31M	31	Missense	distal	-5	no	32.135	33.168	EPSD	COSMIC	28.094	Up-regulation
TK_Ret_RET_Y	P28482	MAPK1	P07949	RET	Y187	F183S	183	Missense	distal	-4	no	57.218	67.173	PhosphoSitePlus	COSMIC	28.094	Up-regulation
TK_Ret_RET_Y	P28482	MAPK1	P07949	RET	Y205	I211V	211	Missense	distal	6	no	35.107	36.174	EPSD	COSMIC	28.094	Up-regulation
TK_Ret_RET_Y	P28482	MAPK1	P07949	RET	Y205	G204C	204	Missense	proximal	-1	no	35.107	35.084	EPSD	COSMIC	28.094	Down-regulation
TK_Ret_RET_Y	P28482	MAPK1	P07949	RET	Y205	T206I	206	Missense	proximal	1	no	35.107	34.695	EPSD	COSMIC	28.094	Down-regulation
TK_Ret_RET_Y	P45983	MAPK8	P07949	RET	Y185	R189G	189	Missense	distal	4	no	57.788	56.099	PhosphoSitePlus	COSMIC	28.094	Down-regulation
TK_Ret_RET_Y	P45983	MAPK8	P07949	RET	Y185	T183A	183	Missense	proximal	-2	no	57.788	58.366	PhosphoSitePlus	COSMIC	28.094	Up-regulation
TK_Ret_RET_Y	P27361	MAPK3	P07949	RET	Y204	G199D	199	Missense	distal	-5	no	57.849	58.926	PhosphoSitePlus	COSMIC	28.094	Up-regulation
TK_Ret_RET_Y	P27361	MAPK3	P07949	RET	Y204	R211Q	211	Missense	distal	7	no	57.849	47.579	PhosphoSitePlus	COSMIC	28.094	Down-regulation
TK_Ret_RET_Y	P27361	MAPK3	P07949	RET	Y204	R211P	211	Missense	distal	7	no	57.849	55.475	PhosphoSitePlus	COSMIC	28.094	Down-regulation
TK_Ret_RET_Y	P27361	MAPK3	P07949	RET	Y204	T202M	202	Missense	proximal	-2	no	57.849	55.741	PhosphoSitePlus	COSMIC	28.094	Down-regulation
TK_Ret_RET_Y	P27361	MAPK3	P07949	RET	Y204	Y204C	204	Missense	central	0	yes	57.849	0.000	PhosphoSitePlus	COSMIC	28.094	Loss
TK_Ret_RET_Y	P27361	MAPK3	P07949	RET	Y204	L201P	201	Missense	distal	-3	no	57.849	59.039	PhosphoSitePlus	COSMIC	28.094	Up-regulation
TK_Ret_RET_Y	P27361	MAPK3	P07949	RET	Y222	S219F	219	Missense	distal	-3	no	34.972	32.143	EPSD	COSMIC	28.094	Down-regulation
TK_Ret_RET_Y	P27361	MAPK3	P07949	RET	Y222	M216I	216	Missense	distal	-6	no	34.972	34.918	EPSD	COSMIC;CCLE	28.094	Down-regulation
TK_Ret_RET_Y	P27361	MAPK3	P07949	RET	Y222	T223M	223	Missense	proximal	1	no	34.972	36.398	EPSD	COSMIC	28.094	Up-regulation
TK_Ret_RET_Y	Q16539	MAPK14	P07949	RET	Y182	T185I	185	Missense	distal	3	no	61.617	60.381	PhosphoSitePlus	COSMIC	28.094	Down-regulation
TK_Ret_RET_Y	Q16539	MAPK14	P07949	RET	Y258	Q260R	260	Missense	proximal	2	no	32.577	33.142	EPSD	COSMIC	28.094	Up-regulation
AGC_Akt_AKT1_ST	P19634	SLC9A1	P31749	AKT1	S648	R645W	645	Missense	distal	-3	no	15.140	6.199	PhosphoSitePlus;EPSD	COSMIC;GDSC;CCLE	7.780	Loss
AGC_Akt_AKT1_ST	P19634	SLC9A1	P31749	AKT1	S648	R645L	645	Missense	distal	-3	no	15.140	8.146	PhosphoSitePlus;EPSD	COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	P19634	SLC9A1	P31749	AKT1	S703	R700H	700	Missense	distal	-3	no	15.032	10.333	EPSD;PhosphoSitePlus	COSMIC;GDSC;CCLE	7.780	Down-regulation
AGC_Akt_AKT1_ST	P19634	SLC9A1	P31749	AKT1	S770	P772L	772	Missense	proximal	2	no	12.104	11.894	EPSD	COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	P19634	SLC9A1	P31749	AKT1	S770	P772S	772	Missense	proximal	2	no	12.104	12.440	EPSD	COSMIC	7.780	Up-regulation
AGC_Akt_AKT1_ST	P19634	SLC9A1	P31749	AKT1	S787	P780S	780	Missense	distal	-7	no	8.218	8.412	EPSD	COSMIC	7.780	Up-regulation
AGC_Akt_AKT1_ST	P19634	SLC9A1	P31749	AKT1	S787	P786S	786	Missense	proximal	-1	no	8.218	8.247	EPSD	COSMIC	7.780	Up-regulation
AGC_Akt_AKT1_ST	Q06187	BTK	P31749	AKT1	S21	Q16H	16	Missense	distal	-5	no	8.937	10.070	EPSD	COSMIC	7.780	Up-regulation
AGC_Akt_AKT1_ST	Q06187	BTK	P31749	AKT1	S21	S14P	14	Missense	distal	-7	no	8.937	8.743	EPSD	COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	Q06187	BTK	P31749	AKT1	S21	S14F	14	Missense	distal	-7	no	8.937	8.659	EPSD	COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	Q06187	BTK	P31749	AKT1	S51	G47R	47	Missense	distal	-4	no	15.721	16.536	EPSD;PhosphoSitePlus	COSMIC;GDSC;CCLE	7.780	Up-regulation
AGC_Akt_AKT1_ST	Q06187	BTK	P31749	AKT1	S51	R46H	46	Missense	distal	-5	no	15.721	12.626	EPSD;PhosphoSitePlus	COSMIC;GDSC;CCLE	7.780	Down-regulation
AGC_Akt_AKT1_ST	Q06187	BTK	P31749	AKT1	S51	D57N	57	Missense	distal	6	no	15.721	15.803	EPSD;PhosphoSitePlus	COSMIC	7.780	Up-regulation
AGC_Akt_AKT1_ST	Q06187	BTK	P31749	AKT1	S51	E45K	45	Missense	distal	-6	no	15.721	15.788	EPSD;PhosphoSitePlus	COSMIC	7.780	Up-regulation
AGC_Akt_AKT1_ST	Q06187	BTK	P31749	AKT1	S86	S93L	93	Missense	distal	7	no	10.175	10.109	EPSD	COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	Q06187	BTK	P31749	AKT1	S86	R82I	82	Missense	distal	-4	no	10.175	8.708	EPSD	COSMIC;CCLE	7.780	Down-regulation
AGC_Akt_AKT1_ST	Q06187	BTK	P31749	AKT1	S86	P80Q	80	Missense	distal	-6	no	10.175	10.189	EPSD	COSMIC	7.780	Up-regulation
AGC_Akt_AKT1_ST	Q06187	BTK	P31749	AKT1	S86	P80S	80	Missense	distal	-6	no	10.175	10.239	EPSD	COSMIC	7.780	Up-regulation
AGC_Akt_AKT1_ST	Q06187	BTK	P31749	AKT1	S86	R82K	82	Missense	distal	-4	no	10.175	10.162	EPSD	COSMIC;GDSC;CCLE	7.780	Down-regulation
AGC_Akt_AKT1_ST	Q06187	BTK	P31749	AKT1	S87	S93L	93	Missense	distal	6	no	8.724	8.620	EPSD	COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	Q06187	BTK	P31749	AKT1	S87	R82I	82	Missense	distal	-5	no	8.724	4.156	EPSD	COSMIC;CCLE	7.780	Loss
AGC_Akt_AKT1_ST	Q06187	BTK	P31749	AKT1	S87	P80Q	80	Missense	distal	-7	no	8.724	8.779	EPSD	COSMIC	7.780	Up-regulation
AGC_Akt_AKT1_ST	Q06187	BTK	P31749	AKT1	S87	P80S	80	Missense	distal	-7	no	8.724	8.918	EPSD	COSMIC	7.780	Up-regulation
AGC_Akt_AKT1_ST	Q06187	BTK	P31749	AKT1	S87	R82K	82	Missense	distal	-5	no	8.724	6.326	EPSD	COSMIC;GDSC;CCLE	7.780	Loss
AGC_Akt_AKT1_ST	Q06187	BTK	P31749	AKT1	S174	S180Y	180	Missense	distal	6	no	13.063	12.975	EPSD	COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	Q06187	BTK	P31749	AKT1	S174	G178W	178	Missense	distal	4	no	13.063	13.148	EPSD	COSMIC	7.780	Up-regulation
AGC_Akt_AKT1_ST	Q06187	BTK	P31749	AKT1	S174	G173E	173	Missense	proximal	-1	no	13.063	13.079	EPSD	COSMIC	7.780	Up-regulation
AGC_Akt_AKT1_ST	Q06187	BTK	P31749	AKT1	S174	L168F	168	Missense	distal	-6	no	13.063	13.039	EPSD	COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	Q06187	BTK	P31749	AKT1	S310	T316A	316	Missense	distal	6	no	9.280	9.177	EPSD	COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	Q06187	BTK	P31749	AKT1	S310	D308N	308	Missense	proximal	-2	no	9.280	9.987	EPSD	COSMIC	7.780	Up-regulation
AGC_Akt_AKT1_ST	Q06187	BTK	P31749	AKT1	S310	A312P	312	Missense	proximal	2	no	9.280	9.319	EPSD	COSMIC	7.780	Up-regulation
AGC_Akt_AKT1_ST	Q06187	BTK	P31749	AKT1	S310	D308Y	308	Missense	proximal	-2	no	9.280	9.751	EPSD	COSMIC	7.780	Up-regulation
AGC_Akt_AKT1_ST	Q06187	BTK	P31749	AKT1	T495	E488K	488	Missense	distal	-7	no	14.279	14.472	PhosphoSitePlus;EPSD	COSMIC	7.780	Up-regulation
AGC_Akt_AKT1_ST	Q06187	BTK	P31749	AKT1	T495	Q496E	496	Missense	proximal	1	no	14.279	14.334	PhosphoSitePlus;EPSD	COSMIC	7.780	Up-regulation
AGC_Akt_AKT1_ST	Q06187	BTK	P31749	AKT1	T495	E488G	488	Missense	distal	-7	no	14.279	14.243	PhosphoSitePlus;EPSD	COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	Q06187	BTK	P31749	AKT1	T495	H491Y	491	Missense	distal	-4	no	14.279	14.393	PhosphoSitePlus;EPSD	COSMIC	7.780	Up-regulation
AGC_Akt_AKT1_ST	Q06187	BTK	P31749	AKT1	T495	Q494K	494	Missense	proximal	-1	no	14.279	14.308	PhosphoSitePlus;EPSD	COSMIC	7.780	Up-regulation
AGC_Akt_AKT1_ST	Q06187	BTK	P31749	AKT1	S623	V626L	626	Missense	distal	3	no	10.647	10.639	EPSD	COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	Q9NR28	DIABLO	P31749	AKT1	S9	W7R	7	Missense	proximal	-2	no	6.879	8.133	EPSD	COSMIC	7.780	Gain
AGC_Akt_AKT1_ST	Q9NR28	DIABLO	P31749	AKT1	T13	V12L	12	Missense	proximal	-1	no	12.671	12.677	EPSD	COSMIC	7.780	Up-regulation
AGC_Akt_AKT1_ST	Q9NR28	DIABLO	P31749	AKT1	T13	W7R	7	Missense	distal	-6	no	12.671	12.818	EPSD	COSMIC	7.780	Up-regulation
AGC_Akt_AKT1_ST	Q9NR28	DIABLO	P31749	AKT1	S67	Q61R	61	Missense	distal	-6	no	8.220	8.305	PhosphoSitePlus	COSMIC	7.780	Up-regulation
AGC_Akt_AKT1_ST	Q9NR28	DIABLO	P31749	AKT1	S67	A72T	72	Missense	distal	5	no	8.220	8.272	PhosphoSitePlus	COSMIC	7.780	Up-regulation
AGC_Akt_AKT1_ST	Q9NR28	DIABLO	P31749	AKT1	S69	A72T	72	Missense	distal	3	no	7.840	7.897	EPSD	COSMIC	7.780	Up-regulation
AGC_Akt_AKT1_ST	Q9NR28	DIABLO	P31749	AKT1	S69	R76I	76	Missense	distal	7	no	7.840	7.735	EPSD	COSMIC	7.780	Loss
AGC_Akt_AKT1_ST	Q9NR28	DIABLO	P31749	AKT1	T220	R227L	227	Missense	distal	7	no	10.595	10.521	EPSD	COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	Q9NR28	DIABLO	P31749	AKT1	T220	Q221E	221	Missense	proximal	1	no	10.595	10.650	EPSD	COSMIC	7.780	Up-regulation
AGC_Akt_AKT1_ST	Q9NR28	DIABLO	P31749	AKT1	T220	R217H	217	Missense	distal	-3	no	10.595	5.896	EPSD	COSMIC	7.780	Loss
AGC_Akt_AKT1_ST	Q9NR28	DIABLO	P31749	AKT1	S230	R227L	227	Missense	distal	-3	no	13.712	6.718	EPSD	COSMIC	7.780	Loss
AGC_Akt_AKT1_ST	Q9NR28	DIABLO	P31749	AKT1	S230	R237C	237	Missense	distal	7	no	13.712	13.582	EPSD	COSMIC;CCLE	7.780	Down-regulation
AGC_Akt_AKT1_ST	O43521	BCL2L11	P31749	AKT1	T34	A32D	32	Missense	proximal	-2	no	8.560	7.619	EPSD	COSMIC	7.780	Loss
AGC_Akt_AKT1_ST	O43521	BCL2L11	P31749	AKT1	T34	A32T	32	Missense	proximal	-2	no	8.560	8.945	EPSD	COSMIC	7.780	Up-regulation
AGC_Akt_AKT1_ST	O43521	BCL2L11	P31749	AKT1	T34	R29S	29	Missense	distal	-5	no	8.560	4.090	EPSD	COSMIC	7.780	Loss
AGC_Akt_AKT1_ST	O43521	BCL2L11	P31749	AKT1	T34	R29K	29	Missense	distal	-5	no	8.560	6.163	EPSD	COSMIC	7.780	Loss
AGC_Akt_AKT1_ST	O43521	BCL2L11	P31749	AKT1	S87	S86T	86	Missense	proximal	-1	no	10.333	10.339	PhosphoSitePlus	COSMIC	7.780	Up-regulation
AGC_Akt_AKT1_ST	O43521	BCL2L11	P31749	AKT1	S87	S93F	93	Missense	distal	6	no	10.333	10.213	PhosphoSitePlus	COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	O43521	BCL2L11	P31749	AKT1	S87	R84K	84	Missense	distal	-3	no	10.333	5.812	PhosphoSitePlus	COSMIC	7.780	Loss
AGC_Akt_AKT1_ST	O43521	BCL2L11	P31749	AKT1	S87	S94T	94	Missense	distal	7	no	10.333	10.343	PhosphoSitePlus	COSMIC	7.780	Up-regulation
AGC_Akt_AKT1_ST	O43521	BCL2L11	P31749	AKT1	S90	S86T	86	Missense	distal	-4	no	8.219	8.275	EPSD	COSMIC	7.780	Up-regulation
AGC_Akt_AKT1_ST	O43521	BCL2L11	P31749	AKT1	S90	F97L	97	Missense	distal	7	no	8.219	8.226	EPSD	COSMIC	7.780	Up-regulation
AGC_Akt_AKT1_ST	O43521	BCL2L11	P31749	AKT1	S90	S93F	93	Missense	distal	3	no	8.219	8.120	EPSD	COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	O43521	BCL2L11	P31749	AKT1	S90	R84K	84	Missense	distal	-6	no	8.219	8.204	EPSD	COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	O43521	BCL2L11	P31749	AKT1	S90	S94T	94	Missense	distal	4	no	8.219	8.214	EPSD	COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	O43521	BCL2L11	P31749	AKT1	S94	F97L	97	Missense	distal	3	no	13.394	13.395	EPSD	COSMIC	7.780	Up-regulation
AGC_Akt_AKT1_ST	O43521	BCL2L11	P31749	AKT1	S94	D100G	100	Missense	distal	6	no	13.394	13.438	EPSD	COSMIC	7.780	Up-regulation
AGC_Akt_AKT1_ST	O43521	BCL2L11	P31749	AKT1	S94	S93F	93	Missense	proximal	-1	no	13.394	13.359	EPSD	COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	O43521	BCL2L11	P31749	AKT1	S109	S104R	104	Missense	distal	-5	no	4.663	9.133	EPSD	COSMIC	7.780	Gain
AGC_Akt_AKT1_ST	P29474	NOS3	P31749	AKT1	S102	P106S	106	Missense	distal	4	no	10.188	10.033	EPSD	COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	P29474	NOS3	P31749	AKT1	S260	P265L	265	Missense	distal	5	no	7.871	7.857	EPSD	COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	P29474	NOS3	P31749	AKT1	S260	D264N	264	Missense	distal	4	no	7.871	7.755	EPSD	COSMIC	7.780	Loss
AGC_Akt_AKT1_ST	P29474	NOS3	P31749	AKT1	S260	G259V	259	Missense	proximal	-1	no	7.871	7.865	EPSD	COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	P29474	NOS3	P31749	AKT1	T495	G489S	489	Missense	distal	-6	no	11.190	11.269	EPSD	COSMIC	7.780	Up-regulation
AGC_Akt_AKT1_ST	P29474	NOS3	P31749	AKT1	T495	G489D	489	Missense	distal	-6	no	11.190	11.151	EPSD	COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	P29474	NOS3	P31749	AKT1	S615	K610Q	610	Missense	distal	-5	no	11.942	10.111	PhosphoSitePlus;EPSD	COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	P29474	NOS3	P31749	AKT1	S633	D637H	637	Missense	distal	4	no	17.774	17.745	EPSD	COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	P29474	NOS3	P31749	AKT1	S633	N635T	635	Missense	proximal	2	no	17.774	17.969	EPSD	COSMIC	7.780	Up-regulation
AGC_Akt_AKT1_ST	P29474	NOS3	P31749	AKT1	S634	D637H	637	Missense	distal	3	no	10.558	10.570	EPSD	COSMIC	7.780	Up-regulation
AGC_Akt_AKT1_ST	P29474	NOS3	P31749	AKT1	S634	A641T	641	Missense	distal	7	no	10.558	10.619	EPSD	COSMIC	7.780	Up-regulation
AGC_Akt_AKT1_ST	P29474	NOS3	P31749	AKT1	S634	N635T	635	Missense	proximal	1	no	10.558	10.840	EPSD	COSMIC	7.780	Up-regulation
AGC_Akt_AKT1_ST	P29474	NOS3	P31749	AKT1	T785	Q788L	788	Missense	distal	3	no	9.168	9.143	EPSD	COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	P29474	NOS3	P31749	AKT1	T785	R782H	782	Missense	distal	-3	no	9.168	4.469	EPSD	COSMIC;CCLE	7.780	Loss
AGC_Akt_AKT1_ST	P29474	NOS3	P31749	AKT1	S1202	S1198L	1198	Missense	distal	-4	no	7.845	6.721	EPSD	COSMIC	7.780	Loss
AGC_Akt_AKT1_ST	Q86V81	ALYREF	P31749	AKT1	T219	R224G	224	Missense	distal	5	no	11.247	11.176	EPSD;PhosphoSitePlus	COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	P19484	TFEB	P31749	AKT1	S142	N137H	137	Missense	distal	-5	no	6.525	7.915	EPSD	COSMIC	7.780	Gain
AGC_Akt_AKT1_ST	P19484	TFEB	P31749	AKT1	S227	R234Q	234	Missense	distal	7	no	7.870	7.814	EPSD	COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	P19484	TFEB	P31749	AKT1	S227	E221D	221	Missense	distal	-6	no	7.870	7.798	EPSD	COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	P19484	TFEB	P31749	AKT1	S463	R464C	464	Missense	proximal	1	no	11.685	11.157	EPSD	COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	P19484	TFEB	P31749	AKT1	S463	A458S	458	Missense	distal	-5	no	11.685	11.069	EPSD	COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	P19484	TFEB	P31749	AKT1	S463	S462N	462	Missense	proximal	-1	no	11.685	11.667	EPSD	COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	P19484	TFEB	P31749	AKT1	S467	R464C	464	Missense	distal	-3	no	15.178	9.005	PhosphoSitePlus	COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	P19484	TFEB	P31749	AKT1	S467	S462N	462	Missense	distal	-5	no	15.178	15.164	PhosphoSitePlus	COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	P19484	TFEB	P31749	AKT1	S469	R464C	464	Missense	distal	-5	no	11.305	7.228	EPSD	COSMIC	7.780	Loss
AGC_Akt_AKT1_ST	P19484	TFEB	P31749	AKT1	S469	S462N	462	Missense	distal	-7	no	11.305	11.191	EPSD	COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	P31749	AKT1	P31749	AKT1	T65	L62R	62	Missense	distal	-3	no	2.611	9.605	EPSD	COSMIC	7.780	Gain
AGC_Akt_AKT1_ST	P31749	AKT1	P31749	AKT1	T72	C77F	77	Missense	distal	5	no	15.377	15.424	PhosphoSitePlus;EPSD	COSMIC	7.780	Up-regulation
AGC_Akt_AKT1_ST	P31749	AKT1	P31749	AKT1	T72	R67Q	67	Missense	distal	-5	no	15.377	11.150	PhosphoSitePlus;EPSD	COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	P31749	AKT1	P31749	AKT1	T72	R76H	76	Missense	distal	4	no	15.377	15.562	PhosphoSitePlus;EPSD	COSMIC	7.780	Up-regulation
AGC_Akt_AKT1_ST	P31749	AKT1	P31749	AKT1	T72	R69L	69	Missense	distal	-3	no	15.377	8.383	PhosphoSitePlus;EPSD	COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	P31749	AKT1	P31749	AKT1	T72	Q79R	79	Missense	distal	7	no	15.377	15.433	PhosphoSitePlus;EPSD	COSMIC	7.780	Up-regulation
AGC_Akt_AKT1_ST	P31749	AKT1	P31749	AKT1	T72	P70L	70	Missense	proximal	-2	no	15.377	15.345	PhosphoSitePlus;EPSD	COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	P31749	AKT1	P31749	AKT1	S124	G123D	123	Missense	proximal	-1	no	10.847	10.828	EPSD	COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	P31749	AKT1	P31749	AKT1	S124	D127N	127	Missense	distal	3	no	10.847	10.902	EPSD	COSMIC	7.780	Up-regulation
AGC_Akt_AKT1_ST	P31749	AKT1	P31749	AKT1	S124	G130R	130	Missense	distal	6	no	10.847	10.950	EPSD	COSMIC	7.780	Up-regulation
AGC_Akt_AKT1_ST	P31749	AKT1	P31749	AKT1	S126	G123D	123	Missense	distal	-3	no	8.454	9.259	EPSD	COSMIC	7.780	Up-regulation
AGC_Akt_AKT1_ST	P31749	AKT1	P31749	AKT1	S126	D127N	127	Missense	proximal	1	no	8.454	8.578	EPSD	COSMIC	7.780	Up-regulation
AGC_Akt_AKT1_ST	P31749	AKT1	P31749	AKT1	S126	E133Q	133	Missense	distal	7	no	8.454	8.439	EPSD	COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	P31749	AKT1	P31749	AKT1	S126	G130R	130	Missense	distal	4	no	8.454	8.291	EPSD	COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	P31749	AKT1	P31749	AKT1	S246	S240P	240	Missense	distal	-6	no	15.300	15.236	EPSD;PhosphoSitePlus	COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	P31749	AKT1	P31749	AKT1	S246	A250V	250	Missense	distal	4	no	15.300	15.356	EPSD;PhosphoSitePlus	COSMIC	7.780	Up-regulation
AGC_Akt_AKT1_ST	P31749	AKT1	P31749	AKT1	S246	Y253C	253	Missense	distal	7	no	15.300	15.221	EPSD;PhosphoSitePlus	COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	P31749	AKT1	P31749	AKT1	S246	R243H	243	Missense	distal	-3	no	15.300	10.602	EPSD;PhosphoSitePlus	COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	P31749	AKT1	P31749	AKT1	S246	S240C	240	Missense	distal	-6	no	15.300	15.154	EPSD;PhosphoSitePlus	COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	P31749	AKT1	P31749	AKT1	S396	S396F	396	Missense	central	0	yes	7.852	0.000	EPSD	COSMIC	7.780	Loss
AGC_Akt_AKT1_ST	P31749	AKT1	P31749	AKT1	S396	G394W	394	Missense	proximal	-2	no	7.852	7.105	EPSD	COSMIC	7.780	Loss
AGC_Akt_AKT1_ST	P31749	AKT1	P31749	AKT1	S396	G395S	395	Missense	proximal	-1	no	7.852	7.882	EPSD	COSMIC	7.780	Up-regulation
AGC_Akt_AKT1_ST	P31749	AKT1	P31749	AKT1	S396	A399T	399	Missense	distal	3	no	7.852	7.909	EPSD	COSMIC	7.780	Up-regulation
AGC_Akt_AKT1_ST	P31749	AKT1	P31749	AKT1	S422	V416M	416	Missense	distal	-6	no	8.142	8.155	EPSD	COSMIC	7.780	Up-regulation
AGC_Akt_AKT1_ST	P31749	AKT1	P31749	AKT1	S422	S422R	422	Missense	central	0	yes	8.142	0.000	EPSD	COSMIC	7.780	Loss
AGC_Akt_AKT1_ST	P31749	AKT1	P31749	AKT1	S473	S477N	477	Missense	distal	4	no	7.952	8.061	EPSD	COSMIC	7.780	Up-regulation
AGC_Akt_AKT1_ST	P31749	AKT1	P31749	AKT1	S473	P470L	470	Missense	distal	-3	no	7.952	7.598	EPSD	COSMIC	7.780	Loss
AGC_Akt_AKT1_ST	P31749	AKT1	P31749	AKT1	S475	S477N	477	Missense	proximal	2	no	7.786	7.517	EPSD	COSMIC	7.780	Loss
AGC_Akt_AKT1_ST	P31749	AKT1	P31749	AKT1	S475	P470L	470	Missense	distal	-5	no	7.786	7.670	EPSD	COSMIC	7.780	Loss
AGC_Akt_AKT1_ST	P19174	PLCG1	P31749	AKT1	T513	H508R	508	Missense	distal	-5	no	5.361	8.456	EPSD	COSMIC	7.780	Gain
AGC_Akt_AKT1_ST	P19174	PLCG1	P31749	AKT1	S539	P535S	535	Missense	distal	-4	no	7.472	8.208	EPSD	COSMIC	7.780	Gain
AGC_Akt_AKT1_ST	P19174	PLCG1	P31749	AKT1	S582	G577R	577	Missense	distal	-5	no	4.074	8.138	EPSD	COSMIC	7.780	Gain
AGC_Akt_AKT1_ST	P19174	PLCG1	P31749	AKT1	S701	I704M	704	Missense	distal	3	no	8.721	8.767	EPSD	COSMIC	7.780	Up-regulation
AGC_Akt_AKT1_ST	P19174	PLCG1	P31749	AKT1	S701	R707L	707	Missense	distal	6	no	8.721	8.619	EPSD	COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	P19174	PLCG1	P31749	AKT1	S701	S705C	705	Missense	distal	4	no	8.721	9.066	EPSD	COSMIC	7.780	Up-regulation
AGC_Akt_AKT1_ST	P19174	PLCG1	P31749	AKT1	S981	P984L	984	Missense	distal	3	no	10.532	10.515	EPSD	COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	P19174	PLCG1	P31749	AKT1	S981	R978Q	978	Missense	distal	-3	no	10.532	3.320	EPSD	COSMIC	7.780	Loss
AGC_Akt_AKT1_ST	P19174	PLCG1	P31749	AKT1	S1248	H1241Y	1241	Missense	distal	-7	no	14.465	14.504	PhosphoSitePlus	COSMIC;CCLE	7.780	Up-regulation
AGC_Akt_AKT1_ST	P19174	PLCG1	P31749	AKT1	S1248	G1247A	1247	Missense	proximal	-1	no	14.465	14.473	PhosphoSitePlus	COSMIC	7.780	Up-regulation
AGC_Akt_AKT1_ST	P19174	PLCG1	P31749	AKT1	S1248	A1244T	1244	Missense	distal	-4	no	14.465	15.243	PhosphoSitePlus	COSMIC	7.780	Up-regulation
AGC_Akt_AKT1_ST	P19174	PLCG1	P31749	AKT1	S1248	Q1254K	1254	Missense	distal	6	no	14.465	14.547	PhosphoSitePlus	COSMIC	7.780	Up-regulation
AGC_Akt_AKT1_ST	P29375	KDM5A	P31749	AKT1	T223	Q224R	224	Missense	proximal	1	no	12.552	12.847	EPSD	COSMIC	7.780	Up-regulation
AGC_Akt_AKT1_ST	P29375	KDM5A	P31749	AKT1	T223	R219K	219	Missense	distal	-4	no	12.552	12.538	EPSD	COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	P29375	KDM5A	P31749	AKT1	T223	R220L	220	Missense	distal	-3	no	12.552	5.558	EPSD	COSMIC	7.780	Loss
AGC_Akt_AKT1_ST	P29375	KDM5A	P31749	AKT1	T223	R220H	220	Missense	distal	-3	no	12.552	7.853	EPSD	COSMIC;GDSC;CCLE	7.780	Down-regulation
AGC_Akt_AKT1_ST	P29375	KDM5A	P31749	AKT1	T223	D229H	229	Missense	distal	6	no	12.552	12.581	EPSD	COSMIC	7.780	Up-regulation
AGC_Akt_AKT1_ST	P29375	KDM5A	P31749	AKT1	S225	Q224R	224	Missense	proximal	-1	no	13.181	13.214	EPSD;PhosphoSitePlus	COSMIC	7.780	Up-regulation
AGC_Akt_AKT1_ST	P29375	KDM5A	P31749	AKT1	S225	R219K	219	Missense	distal	-6	no	13.181	13.167	EPSD;PhosphoSitePlus	COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	P29375	KDM5A	P31749	AKT1	S225	R220L	220	Missense	distal	-5	no	13.181	9.055	EPSD;PhosphoSitePlus	COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	P29375	KDM5A	P31749	AKT1	S225	R220H	220	Missense	distal	-5	no	13.181	10.087	EPSD;PhosphoSitePlus	COSMIC;GDSC;CCLE	7.780	Down-regulation
AGC_Akt_AKT1_ST	P29375	KDM5A	P31749	AKT1	S225	D229H	229	Missense	distal	4	no	13.181	13.152	EPSD;PhosphoSitePlus	COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	P29375	KDM5A	P31749	AKT1	S227	Q224R	224	Missense	distal	-3	no	7.266	14.477	EPSD	COSMIC	7.780	Gain
AGC_Akt_AKT1_ST	P29375	KDM5A	P31749	AKT1	T285	M279I	279	Missense	distal	-6	no	16.140	16.082	EPSD;PhosphoSitePlus	COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	P29375	KDM5A	P31749	AKT1	T285	F290L	290	Missense	distal	5	no	16.140	16.146	EPSD;PhosphoSitePlus	COSMIC	7.780	Up-regulation
AGC_Akt_AKT1_ST	P29375	KDM5A	P31749	AKT1	T285	K283T	283	Missense	proximal	-2	no	16.140	15.823	EPSD;PhosphoSitePlus	COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	P29375	KDM5A	P31749	AKT1	T285	D292N	292	Missense	distal	7	no	16.140	16.182	EPSD;PhosphoSitePlus	COSMIC	7.780	Up-regulation
AGC_Akt_AKT1_ST	P29375	KDM5A	P31749	AKT1	T285	R282G	282	Missense	distal	-3	no	16.140	9.384	EPSD;PhosphoSitePlus	COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	P29375	KDM5A	P31749	AKT1	T285	V291F	291	Missense	distal	6	no	16.140	16.134	EPSD;PhosphoSitePlus	COSMIC;GDSC	7.780	Down-regulation
AGC_Akt_AKT1_ST	P29375	KDM5A	P31749	AKT1	S287	Y294F	294	Missense	distal	7	no	10.380	10.349	PhosphoSitePlus;EPSD	COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	P29375	KDM5A	P31749	AKT1	S287	F290L	290	Missense	distal	3	no	10.380	10.381	PhosphoSitePlus;EPSD	COSMIC	7.780	Up-regulation
AGC_Akt_AKT1_ST	P29375	KDM5A	P31749	AKT1	S287	K283T	283	Missense	distal	-4	no	10.380	10.364	PhosphoSitePlus;EPSD	COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	P29375	KDM5A	P31749	AKT1	S287	D292N	292	Missense	distal	5	no	10.380	10.420	PhosphoSitePlus;EPSD	COSMIC	7.780	Up-regulation
AGC_Akt_AKT1_ST	P29375	KDM5A	P31749	AKT1	S287	L293P	293	Missense	distal	6	no	10.380	10.390	PhosphoSitePlus;EPSD	COSMIC	7.780	Up-regulation
AGC_Akt_AKT1_ST	P29375	KDM5A	P31749	AKT1	S287	R282G	282	Missense	distal	-5	no	10.380	6.316	PhosphoSitePlus;EPSD	COSMIC	7.780	Loss
AGC_Akt_AKT1_ST	P29375	KDM5A	P31749	AKT1	S287	V291F	291	Missense	distal	4	no	10.380	10.396	PhosphoSitePlus;EPSD	COSMIC;GDSC	7.780	Up-regulation
AGC_Akt_AKT1_ST	P29375	KDM5A	P31749	AKT1	T362	Y361S	361	Missense	proximal	-1	no	10.750	10.776	EPSD	COSMIC	7.780	Up-regulation
AGC_Akt_AKT1_ST	P29375	KDM5A	P31749	AKT1	T362	Y361H	361	Missense	proximal	-1	no	10.750	10.742	EPSD	COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	P29375	KDM5A	P31749	AKT1	S399	R396W	396	Missense	distal	-3	no	10.261	1.320	EPSD	COSMIC	7.780	Loss
AGC_Akt_AKT1_ST	P29375	KDM5A	P31749	AKT1	S399	R396Q	396	Missense	distal	-3	no	10.261	3.050	EPSD	COSMIC	7.780	Loss
AGC_Akt_AKT1_ST	P29375	KDM5A	P31749	AKT1	S399	E402K	402	Missense	distal	3	no	10.261	10.304	EPSD	COSMIC	7.780	Up-regulation
AGC_Akt_AKT1_ST	P29375	KDM5A	P31749	AKT1	S399	L397Q	397	Missense	proximal	-2	no	10.261	10.417	EPSD	COSMIC	7.780	Up-regulation
AGC_Akt_AKT1_ST	P29375	KDM5A	P31749	AKT1	S811	Q810R	810	Missense	proximal	-1	no	8.345	8.377	EPSD	COSMIC	7.780	Up-regulation
AGC_Akt_AKT1_ST	P29375	KDM5A	P31749	AKT1	S811	H808L	808	Missense	distal	-3	no	8.345	6.050	EPSD	COSMIC	7.780	Loss
AGC_Akt_AKT1_ST	P29375	KDM5A	P31749	AKT1	S811	R816S	816	Missense	distal	5	no	8.345	8.338	EPSD	COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	P29375	KDM5A	P31749	AKT1	S811	R809K	809	Missense	proximal	-2	no	8.345	8.784	EPSD	COSMIC	7.780	Up-regulation
AGC_Akt_AKT1_ST	P29375	KDM5A	P31749	AKT1	S811	T817A	817	Missense	distal	6	no	8.345	8.242	EPSD	COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	P29375	KDM5A	P31749	AKT1	S811	T817I	817	Missense	distal	6	no	8.345	8.160	EPSD	COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	P29375	KDM5A	P31749	AKT1	S1067	H1068D	1068	Missense	proximal	1	no	8.000	7.964	EPSD	COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	P29375	KDM5A	P31749	AKT1	S1067	S1066F	1066	Missense	proximal	-1	no	8.000	7.965	EPSD	COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	P29375	KDM5A	P31749	AKT1	S1067	S1066C	1066	Missense	proximal	-1	no	8.000	7.939	EPSD	COSMIC;GDSC	7.780	Down-regulation
AGC_Akt_AKT1_ST	P29375	KDM5A	P31749	AKT1	S1067	K1064N	1064	Missense	distal	-3	no	8.000	5.043	EPSD	COSMIC	7.780	Loss
AGC_Akt_AKT1_ST	P29375	KDM5A	P31749	AKT1	T1225	R1220S	1220	Missense	distal	-5	no	15.216	10.745	EPSD;PhosphoSitePlus	COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	P29375	KDM5A	P31749	AKT1	S1255	Q1262H	1262	Missense	distal	7	no	12.019	12.003	EPSD;PhosphoSitePlus	COSMIC;GDSC;CCLE	7.780	Down-regulation
AGC_Akt_AKT1_ST	P29375	KDM5A	P31749	AKT1	S1255	R1252C	1252	Missense	distal	-3	no	12.019	5.845	EPSD;PhosphoSitePlus	COSMIC	7.780	Loss
AGC_Akt_AKT1_ST	P29375	KDM5A	P31749	AKT1	T1292	A1288T	1288	Missense	distal	-4	no	11.073	11.851	EPSD	COSMIC	7.780	Up-regulation
AGC_Akt_AKT1_ST	P29375	KDM5A	P31749	AKT1	S1326	S1331P	1331	Missense	distal	5	no	11.803	11.750	EPSD	COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	P29375	KDM5A	P31749	AKT1	S1326	R1323L	1323	Missense	distal	-3	no	11.803	4.809	EPSD	COSMIC	7.780	Loss
AGC_Akt_AKT1_ST	P29375	KDM5A	P31749	AKT1	S1410	P1416R	1416	Missense	distal	6	no	8.778	8.870	EPSD	COSMIC	7.780	Up-regulation
AGC_Akt_AKT1_ST	P29375	KDM5A	P31749	AKT1	S1410	S1414G	1414	Missense	distal	4	no	8.778	8.952	EPSD	COSMIC	7.780	Up-regulation
AGC_Akt_AKT1_ST	P29375	KDM5A	P31749	AKT1	S1410	P1416Q	1416	Missense	distal	6	no	8.778	8.799	EPSD	COSMIC	7.780	Up-regulation
AGC_Akt_AKT1_ST	P29375	KDM5A	P31749	AKT1	S1410	P1416S	1416	Missense	distal	6	no	8.778	8.872	EPSD	COSMIC	7.780	Up-regulation
AGC_Akt_AKT1_ST	P29375	KDM5A	P31749	AKT1	S1410	R1417K	1417	Missense	distal	7	no	8.778	8.771	EPSD	COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	P29375	KDM5A	P31749	AKT1	S1423	P1416R	1416	Missense	distal	-7	no	7.576	7.826	EPSD	COSMIC	7.780	Gain
AGC_Akt_AKT1_ST	P49815	TSC2	P31749	AKT1	S311	G305E	305	Missense	distal	-6	no	11.618	11.652	EPSD	COSMIC	7.780	Up-regulation
AGC_Akt_AKT1_ST	P49815	TSC2	P31749	AKT1	S311	A306T	306	Missense	distal	-5	no	11.618	11.743	EPSD	COSMIC	7.780	Up-regulation
AGC_Akt_AKT1_ST	P49815	TSC2	P31749	AKT1	S311	Y310C	310	Missense	proximal	-1	no	11.618	11.584	EPSD	COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	P49815	TSC2	P31749	AKT1	S311	P316L	316	Missense	distal	5	no	11.618	11.605	EPSD	COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	P49815	TSC2	P31749	AKT1	S311	S311Y	311	Missense	central	0	yes	11.618	0.000	EPSD	COSMIC	7.780	Loss
AGC_Akt_AKT1_ST	P49815	TSC2	P31749	AKT1	S311	G305V	305	Missense	distal	-6	no	11.618	11.622	EPSD	COSMIC	7.780	Up-regulation
AGC_Akt_AKT1_ST	P49815	TSC2	P31749	AKT1	S311	A306S	306	Missense	distal	-5	no	11.618	11.003	EPSD	COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	P49815	TSC2	P31749	AKT1	S540	S540F	540	Missense	central	0	yes	11.290	0.000	EPSD	COSMIC	7.780	Loss
AGC_Akt_AKT1_ST	P49815	TSC2	P31749	AKT1	S540	P542L	542	Missense	proximal	2	no	11.290	11.081	EPSD	COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	P49815	TSC2	P31749	AKT1	S540	S538P	538	Missense	proximal	-2	no	11.290	10.466	EPSD	COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	P49815	TSC2	P31749	AKT1	S540	L539F	539	Missense	proximal	-1	no	11.290	11.284	EPSD	COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	P49815	TSC2	P31749	AKT1	S540	P543Q	543	Missense	distal	3	no	11.290	11.299	EPSD	COSMIC	7.780	Up-regulation
AGC_Akt_AKT1_ST	P49815	TSC2	P31749	AKT1	T603	Y598C	598	Missense	distal	-5	no	7.292	7.823	EPSD	COSMIC	7.780	Gain
AGC_Akt_AKT1_ST	P49815	TSC2	P31749	AKT1	S937	E942K	942	Missense	distal	5	no	11.585	11.619	EPSD	COSMIC	7.780	Up-regulation
AGC_Akt_AKT1_ST	P49815	TSC2	P31749	AKT1	S937	R936Q	936	Missense	proximal	-1	no	11.585	11.553	EPSD	COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	P49815	TSC2	P31749	AKT1	S937	A935S	935	Missense	proximal	-2	no	11.585	12.038	EPSD	COSMIC	7.780	Up-regulation
AGC_Akt_AKT1_ST	P49815	TSC2	P31749	AKT1	S937	S932N	932	Missense	distal	-5	no	11.585	11.571	EPSD	COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	P49815	TSC2	P31749	AKT1	S937	T938I	938	Missense	proximal	1	no	11.585	11.144	EPSD	COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	P49815	TSC2	P31749	AKT1	S939	E942K	942	Missense	distal	3	no	15.360	15.403	EPSD;PhosphoSitePlus	COSMIC	7.780	Up-regulation
AGC_Akt_AKT1_ST	P49815	TSC2	P31749	AKT1	S939	R936Q	936	Missense	distal	-3	no	15.360	8.149	EPSD;PhosphoSitePlus	COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	P49815	TSC2	P31749	AKT1	S939	K945E	945	Missense	distal	6	no	15.360	15.291	EPSD;PhosphoSitePlus	COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	P49815	TSC2	P31749	AKT1	S939	A935S	935	Missense	distal	-4	no	15.360	16.082	EPSD;PhosphoSitePlus	COSMIC	7.780	Up-regulation
AGC_Akt_AKT1_ST	P49815	TSC2	P31749	AKT1	S939	S932N	932	Missense	distal	-7	no	15.360	15.246	EPSD;PhosphoSitePlus	COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	P49815	TSC2	P31749	AKT1	S939	S946I	946	Missense	distal	7	no	15.360	15.262	EPSD;PhosphoSitePlus	COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	P49815	TSC2	P31749	AKT1	S939	T938I	938	Missense	proximal	-1	no	15.360	15.305	EPSD;PhosphoSitePlus	COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	P49815	TSC2	P31749	AKT1	S946	E942K	942	Missense	distal	-4	no	10.866	11.450	EPSD	COSMIC	7.780	Up-regulation
AGC_Akt_AKT1_ST	P49815	TSC2	P31749	AKT1	S946	K945E	945	Missense	proximal	-1	no	10.866	10.845	EPSD	COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	P49815	TSC2	P31749	AKT1	S946	S946I	946	Missense	central	0	yes	10.866	0.000	EPSD	COSMIC	7.780	Loss
AGC_Akt_AKT1_ST	P49815	TSC2	P31749	AKT1	S979	S979R	979	Missense	central	0	yes	9.108	0.000	EPSD	COSMIC	7.780	Loss
AGC_Akt_AKT1_ST	P49815	TSC2	P31749	AKT1	S979	E984V	984	Missense	distal	5	no	9.108	9.081	EPSD	COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	P49815	TSC2	P31749	AKT1	S979	R976W	976	Missense	distal	-3	no	9.108	0.168	EPSD	COSMIC	7.780	Loss
AGC_Akt_AKT1_ST	P49815	TSC2	P31749	AKT1	S979	S981R	981	Missense	proximal	2	no	9.108	8.936	EPSD	COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	P49815	TSC2	P31749	AKT1	S979	V982I	982	Missense	distal	3	no	9.108	9.067	EPSD	COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	P49815	TSC2	P31749	AKT1	S981	R988Q	988	Missense	distal	7	no	14.283	14.227	EPSD;PhosphoSitePlus	COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	P49815	TSC2	P31749	AKT1	S981	S979R	979	Missense	proximal	-2	no	14.283	14.094	EPSD;PhosphoSitePlus	COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	P49815	TSC2	P31749	AKT1	S981	E984V	984	Missense	distal	3	no	14.283	14.234	EPSD;PhosphoSitePlus	COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	P49815	TSC2	P31749	AKT1	S981	R976W	976	Missense	distal	-5	no	14.283	8.763	EPSD;PhosphoSitePlus	COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	P49815	TSC2	P31749	AKT1	S981	S981R	981	Missense	central	0	yes	14.283	0.000	EPSD;PhosphoSitePlus	COSMIC	7.780	Loss
AGC_Akt_AKT1_ST	P49815	TSC2	P31749	AKT1	S981	V982I	982	Missense	proximal	1	no	14.283	14.035	EPSD;PhosphoSitePlus	COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	P49815	TSC2	P31749	AKT1	S981	V987A	987	Missense	distal	6	no	14.283	14.314	EPSD;PhosphoSitePlus	COSMIC	7.780	Up-regulation
AGC_Akt_AKT1_ST	P49815	TSC2	P31749	AKT1	S983	R988Q	988	Missense	distal	5	no	9.011	8.960	EPSD	COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	P49815	TSC2	P31749	AKT1	S983	S979R	979	Missense	distal	-4	no	9.011	9.096	EPSD	COSMIC	7.780	Up-regulation
AGC_Akt_AKT1_ST	P49815	TSC2	P31749	AKT1	S983	E984V	984	Missense	proximal	1	no	9.011	9.105	EPSD	COSMIC	7.780	Up-regulation
AGC_Akt_AKT1_ST	P49815	TSC2	P31749	AKT1	S983	R976W	976	Missense	distal	-7	no	9.011	8.588	EPSD	COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	P49815	TSC2	P31749	AKT1	S983	S981R	981	Missense	proximal	-2	no	9.011	8.822	EPSD	COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	P49815	TSC2	P31749	AKT1	S983	V982I	982	Missense	proximal	-1	no	9.011	8.996	EPSD	COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	P49815	TSC2	P31749	AKT1	S983	V987A	987	Missense	distal	4	no	9.011	8.955	EPSD	COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	P49815	TSC2	P31749	AKT1	T993	R988Q	988	Missense	distal	-5	no	12.911	8.683	EPSD	COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	P49815	TSC2	P31749	AKT1	T993	T993M	993	Missense	central	0	yes	12.911	0.000	EPSD	COSMIC	7.780	Loss
AGC_Akt_AKT1_ST	P49815	TSC2	P31749	AKT1	T993	S999T	999	Missense	distal	6	no	12.911	12.931	EPSD	COSMIC	7.780	Up-regulation
AGC_Akt_AKT1_ST	P49815	TSC2	P31749	AKT1	T993	S999L	999	Missense	distal	6	no	12.911	12.807	EPSD	COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	P49815	TSC2	P31749	AKT1	T993	V987A	987	Missense	distal	-6	no	12.911	12.931	EPSD	COSMIC	7.780	Up-regulation
AGC_Akt_AKT1_ST	P49815	TSC2	P31749	AKT1	T993	S999P	999	Missense	distal	6	no	12.911	12.817	EPSD	COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	P49815	TSC2	P31749	AKT1	S1079	G1074R	1074	Missense	distal	-5	no	5.985	10.049	EPSD	COSMIC	7.780	Gain
AGC_Akt_AKT1_ST	P49815	TSC2	P31749	AKT1	S1130	V1128I	1128	Missense	proximal	-2	no	15.071	15.020	EPSD	COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	P49815	TSC2	P31749	AKT1	S1130	M1131L	1131	Missense	proximal	1	no	15.071	15.232	EPSD	COSMIC	7.780	Up-regulation
AGC_Akt_AKT1_ST	P49815	TSC2	P31749	AKT1	S1130	A1124V	1124	Missense	distal	-6	no	15.071	15.050	EPSD	COSMIC;CCLE	7.780	Down-regulation
AGC_Akt_AKT1_ST	P49815	TSC2	P31749	AKT1	S1130	R1125Q	1125	Missense	distal	-5	no	15.071	10.843	EPSD	COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	P49815	TSC2	P31749	AKT1	S1130	R1127W	1127	Missense	distal	-3	no	15.071	6.130	EPSD	COSMIC	7.780	Loss
AGC_Akt_AKT1_ST	P49815	TSC2	P31749	AKT1	S1130	S1132L	1132	Missense	proximal	2	no	15.071	14.525	EPSD	COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	P49815	TSC2	P31749	AKT1	S1130	R1129C	1129	Missense	proximal	-1	no	15.071	15.000	EPSD	COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	P49815	TSC2	P31749	AKT1	S1130	S1130C	1130	Missense	central	0	yes	15.071	0.000	EPSD	COSMIC	7.780	Loss
AGC_Akt_AKT1_ST	P49815	TSC2	P31749	AKT1	S1130	H1135R	1135	Missense	distal	5	no	15.071	15.145	EPSD	COSMIC	7.780	Up-regulation
AGC_Akt_AKT1_ST	P49815	TSC2	P31749	AKT1	S1130	G1134S	1134	Missense	distal	4	no	15.071	14.897	EPSD	COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	P49815	TSC2	P31749	AKT1	S1132	V1128I	1128	Missense	distal	-4	no	14.362	14.075	EPSD	COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	P49815	TSC2	P31749	AKT1	S1132	M1131L	1131	Missense	proximal	-1	no	14.362	14.363	EPSD	COSMIC	7.780	Up-regulation
AGC_Akt_AKT1_ST	P49815	TSC2	P31749	AKT1	S1132	R1125Q	1125	Missense	distal	-7	no	14.362	14.168	EPSD	COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	P49815	TSC2	P31749	AKT1	S1132	R1127W	1127	Missense	distal	-5	no	14.362	8.843	EPSD	COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	P49815	TSC2	P31749	AKT1	S1132	S1132L	1132	Missense	central	0	yes	14.362	0.000	EPSD	COSMIC	7.780	Loss
AGC_Akt_AKT1_ST	P49815	TSC2	P31749	AKT1	S1132	R1129C	1129	Missense	distal	-3	no	14.362	8.189	EPSD	COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	P49815	TSC2	P31749	AKT1	S1132	S1130C	1130	Missense	proximal	-2	no	14.362	12.710	EPSD	COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	P49815	TSC2	P31749	AKT1	S1132	H1135R	1135	Missense	distal	3	no	14.362	14.446	EPSD	COSMIC	7.780	Up-regulation
AGC_Akt_AKT1_ST	P49815	TSC2	P31749	AKT1	S1132	G1134S	1134	Missense	proximal	2	no	14.362	14.694	EPSD	COSMIC	7.780	Up-regulation
AGC_Akt_AKT1_ST	P49815	TSC2	P31749	AKT1	T1271	P1265S	1265	Missense	distal	-6	no	11.438	11.502	EPSD	COSMIC	7.780	Up-regulation
AGC_Akt_AKT1_ST	P49815	TSC2	P31749	AKT1	T1271	L1278M	1278	Missense	distal	7	no	11.438	11.446	EPSD	COSMIC	7.780	Up-regulation
AGC_Akt_AKT1_ST	P49815	TSC2	P31749	AKT1	T1271	S1274P	1274	Missense	distal	3	no	11.438	11.357	EPSD	COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	P49815	TSC2	P31749	AKT1	T1271	A1273V	1273	Missense	proximal	2	no	11.438	11.276	EPSD	COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	P49815	TSC2	P31749	AKT1	T1271	R1268G	1268	Missense	distal	-3	no	11.438	4.682	EPSD	COSMIC	7.780	Loss
AGC_Akt_AKT1_ST	P49815	TSC2	P31749	AKT1	T1271	S1276L	1276	Missense	distal	5	no	11.438	11.372	EPSD	COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	P49815	TSC2	P31749	AKT1	T1271	S1274N	1274	Missense	distal	3	no	11.438	11.382	EPSD	COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	P49815	TSC2	P31749	AKT1	T1271	S1269L	1269	Missense	proximal	-2	no	11.438	10.581	EPSD	COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	P49815	TSC2	P31749	AKT1	S1334	S1334C	1334	Missense	central	0	yes	11.126	0.000	EPSD	COSMIC	7.780	Loss
AGC_Akt_AKT1_ST	P49815	TSC2	P31749	AKT1	S1334	S1341F	1341	Missense	distal	7	no	11.126	11.052	EPSD	COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	P49815	TSC2	P31749	AKT1	S1334	R1329H	1329	Missense	distal	-5	no	11.126	8.031	EPSD	COSMIC;GDSC	7.780	Down-regulation
AGC_Akt_AKT1_ST	P49815	TSC2	P31749	AKT1	S1334	A1332V	1332	Missense	proximal	-2	no	11.126	10.388	EPSD	COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	P49815	TSC2	P31749	AKT1	S1334	T1330M	1330	Missense	distal	-4	no	11.126	10.161	EPSD	COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	P49815	TSC2	P31749	AKT1	S1334	S1334R	1334	Missense	central	0	yes	11.126	0.000	EPSD	COSMIC	7.780	Loss
AGC_Akt_AKT1_ST	P49815	TSC2	P31749	AKT1	S1334	R1335Q	1335	Missense	proximal	1	no	11.126	10.831	EPSD	COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	P49815	TSC2	P31749	AKT1	S1337	S1334R	1334	Missense	distal	-3	no	4.807	12.583	EPSD	COSMIC	7.780	Gain
AGC_Akt_AKT1_ST	P49815	TSC2	P31749	AKT1	S1338	S1334C	1334	Missense	distal	-4	no	13.473	11.880	EPSD	COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	P49815	TSC2	P31749	AKT1	S1338	S1341F	1341	Missense	distal	3	no	13.473	13.375	EPSD	COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	P49815	TSC2	P31749	AKT1	S1338	A1332V	1332	Missense	distal	-6	no	13.473	13.452	EPSD	COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	P49815	TSC2	P31749	AKT1	S1338	E1344D	1344	Missense	distal	6	no	13.473	13.383	EPSD	COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	P49815	TSC2	P31749	AKT1	S1338	S1334R	1334	Missense	distal	-4	no	13.473	13.559	EPSD	COSMIC	7.780	Up-regulation
AGC_Akt_AKT1_ST	P49815	TSC2	P31749	AKT1	S1338	R1335Q	1335	Missense	distal	-3	no	13.473	6.262	EPSD	COSMIC	7.780	Loss
AGC_Akt_AKT1_ST	P49815	TSC2	P31749	AKT1	S1340	S1334C	1334	Missense	distal	-6	no	9.262	9.116	EPSD	COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	P49815	TSC2	P31749	AKT1	S1340	S1341F	1341	Missense	proximal	1	no	9.262	9.280	EPSD	COSMIC	7.780	Up-regulation
AGC_Akt_AKT1_ST	P49815	TSC2	P31749	AKT1	S1340	E1344D	1344	Missense	distal	4	no	9.262	9.409	EPSD	COSMIC	7.780	Up-regulation
AGC_Akt_AKT1_ST	P49815	TSC2	P31749	AKT1	S1340	S1334R	1334	Missense	distal	-6	no	9.262	9.297	EPSD	COSMIC	7.780	Up-regulation
AGC_Akt_AKT1_ST	P49815	TSC2	P31749	AKT1	S1340	S1346C	1346	Missense	distal	6	no	9.262	9.059	EPSD	COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	P49815	TSC2	P31749	AKT1	S1340	R1335Q	1335	Missense	distal	-5	no	9.262	5.035	EPSD	COSMIC	7.780	Loss
AGC_Akt_AKT1_ST	P49815	TSC2	P31749	AKT1	S1364	S1365L	1365	Missense	proximal	1	no	9.317	9.416	EPSD	COSMIC	7.780	Up-regulation
AGC_Akt_AKT1_ST	P49815	TSC2	P31749	AKT1	S1364	V1363M	1363	Missense	proximal	-1	no	9.317	9.323	EPSD	COSMIC	7.780	Up-regulation
AGC_Akt_AKT1_ST	P49815	TSC2	P31749	AKT1	S1364	R1361Q	1361	Missense	distal	-3	no	9.317	2.106	EPSD	COSMIC	7.780	Loss
AGC_Akt_AKT1_ST	P49815	TSC2	P31749	AKT1	S1364	G1367S	1367	Missense	distal	3	no	9.317	9.408	EPSD	COSMIC	7.780	Up-regulation
AGC_Akt_AKT1_ST	P49815	TSC2	P31749	AKT1	S1364	S1364F	1364	Missense	central	0	yes	9.317	0.000	EPSD	COSMIC	7.780	Loss
AGC_Akt_AKT1_ST	P49815	TSC2	P31749	AKT1	S1364	P1358H	1358	Missense	distal	-6	no	9.317	9.297	EPSD	COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	P49815	TSC2	P31749	AKT1	S1364	S1371R	1371	Missense	distal	7	no	9.317	9.324	EPSD	COSMIC	7.780	Up-regulation
AGC_Akt_AKT1_ST	P49815	TSC2	P31749	AKT1	S1364	S1364L	1364	Missense	central	0	yes	9.317	0.000	EPSD	COSMIC	7.780	Loss
AGC_Akt_AKT1_ST	P49815	TSC2	P31749	AKT1	S1386	S1383R	1383	Missense	distal	-3	no	5.090	12.867	EPSD	COSMIC	7.780	Gain
AGC_Akt_AKT1_ST	P49815	TSC2	P31749	AKT1	S1387	S1383C	1383	Missense	distal	-4	no	8.028	6.435	EPSD	COSMIC	7.780	Loss
AGC_Akt_AKT1_ST	P49815	TSC2	P31749	AKT1	S1387	S1383N	1383	Missense	distal	-4	no	8.028	7.461	EPSD	COSMIC	7.780	Loss
AGC_Akt_AKT1_ST	P49815	TSC2	P31749	AKT1	S1387	S1387L	1387	Missense	central	0	yes	8.028	0.000	EPSD	COSMIC	7.780	Loss
AGC_Akt_AKT1_ST	P49815	TSC2	P31749	AKT1	S1387	S1383R	1383	Missense	distal	-4	no	8.028	8.114	EPSD	COSMIC	7.780	Up-regulation
AGC_Akt_AKT1_ST	P49815	TSC2	P31749	AKT1	S1387	E1390G	1390	Missense	distal	3	no	8.028	7.978	EPSD	COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	P49815	TSC2	P31749	AKT1	S1387	P1389H	1389	Missense	proximal	2	no	8.028	7.831	EPSD	COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	P49815	TSC2	P31749	AKT1	S1387	S1385F	1385	Missense	proximal	-2	no	8.028	7.161	EPSD	COSMIC	7.780	Loss
AGC_Akt_AKT1_ST	P49815	TSC2	P31749	AKT1	S1387	E1390D	1390	Missense	distal	3	no	8.028	7.957	EPSD	COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	P49815	TSC2	P31749	AKT1	S1388	S1383R	1383	Missense	distal	-5	no	4.170	8.640	EPSD	COSMIC	7.780	Gain
AGC_Akt_AKT1_ST	P49815	TSC2	P31749	AKT1	S1418	E1413D	1413	Missense	distal	-5	no	8.245	8.294	EPSD	COSMIC	7.780	Up-regulation
AGC_Akt_AKT1_ST	P49815	TSC2	P31749	AKT1	S1418	P1412T	1412	Missense	distal	-6	no	8.245	8.340	EPSD	COSMIC	7.780	Up-regulation
AGC_Akt_AKT1_ST	P49815	TSC2	P31749	AKT1	S1418	S1420C	1420	Missense	proximal	2	no	8.245	7.421	EPSD	COSMIC	7.780	Loss
AGC_Akt_AKT1_ST	P49815	TSC2	P31749	AKT1	S1420	E1413D	1413	Missense	distal	-7	no	13.504	13.283	EPSD	COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	P49815	TSC2	P31749	AKT1	S1420	S1427R	1427	Missense	distal	7	no	13.504	13.512	EPSD	COSMIC	7.780	Up-regulation
AGC_Akt_AKT1_ST	P49815	TSC2	P31749	AKT1	S1420	S1420C	1420	Missense	central	0	yes	13.504	0.000	EPSD	COSMIC	7.780	Loss
AGC_Akt_AKT1_ST	P49815	TSC2	P31749	AKT1	T1422	A1429S	1429	Missense	distal	7	no	7.861	7.912	EPSD	COSMIC;GDSC	7.780	Up-regulation
AGC_Akt_AKT1_ST	P49815	TSC2	P31749	AKT1	T1422	A1429V	1429	Missense	distal	7	no	7.861	7.857	EPSD	COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	P49815	TSC2	P31749	AKT1	T1422	S1427R	1427	Missense	distal	5	no	7.861	7.869	EPSD	COSMIC	7.780	Up-regulation
AGC_Akt_AKT1_ST	P49815	TSC2	P31749	AKT1	T1422	S1420C	1420	Missense	proximal	-2	no	7.861	6.209	EPSD	COSMIC	7.780	Loss
AGC_Akt_AKT1_ST	P49815	TSC2	P31749	AKT1	S1454	S1454N	1454	Missense	central	0	yes	10.888	0.000	EPSD	COSMIC	7.780	Loss
AGC_Akt_AKT1_ST	P49815	TSC2	P31749	AKT1	S1454	Y1461H	1461	Missense	distal	7	no	10.888	10.867	EPSD	COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	P49815	TSC2	P31749	AKT1	S1454	R1459Q	1459	Missense	distal	5	no	10.888	10.837	EPSD	COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	P49815	TSC2	P31749	AKT1	S1454	S1454G	1454	Missense	central	0	yes	10.888	0.000	EPSD	COSMIC	7.780	Loss
AGC_Akt_AKT1_ST	P49815	TSC2	P31749	AKT1	S1454	R1451I	1451	Missense	distal	-3	no	10.888	3.807	EPSD	COSMIC	7.780	Loss
AGC_Akt_AKT1_ST	P49815	TSC2	P31749	AKT1	T1462	S1464F	1464	Missense	proximal	2	no	14.274	13.697	PhosphoSitePlus;EPSD	COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	P49815	TSC2	P31749	AKT1	T1462	S1464Y	1464	Missense	proximal	2	no	14.274	13.902	PhosphoSitePlus;EPSD	COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	P49815	TSC2	P31749	AKT1	T1462	Y1461H	1461	Missense	proximal	-1	no	14.274	14.266	PhosphoSitePlus;EPSD	COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	P49815	TSC2	P31749	AKT1	T1462	R1459Q	1459	Missense	distal	-3	no	14.274	7.063	PhosphoSitePlus;EPSD	COSMIC	7.780	Loss
AGC_Akt_AKT1_ST	P49815	TSC2	P31749	AKT1	T1462	I1463N	1463	Missense	proximal	1	no	14.274	14.434	PhosphoSitePlus;EPSD	COSMIC	7.780	Up-regulation
AGC_Akt_AKT1_ST	P49815	TSC2	P31749	AKT1	T1462	D1465N	1465	Missense	distal	3	no	14.274	14.330	PhosphoSitePlus;EPSD	COSMIC	7.780	Up-regulation
AGC_Akt_AKT1_ST	P49815	TSC2	P31749	AKT1	T1462	P1468T	1468	Missense	distal	6	no	14.274	14.389	PhosphoSitePlus;EPSD	COSMIC	7.780	Up-regulation
AGC_Akt_AKT1_ST	P49815	TSC2	P31749	AKT1	T1462	T1462I	1462	Missense	central	0	yes	14.274	0.000	PhosphoSitePlus;EPSD	COSMIC	7.780	Loss
AGC_Akt_AKT1_ST	P49815	TSC2	P31749	AKT1	T1462	S1464C	1464	Missense	proximal	2	no	14.274	13.450	PhosphoSitePlus;EPSD	COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	P49815	TSC2	P31749	AKT1	S1464	S1464F	1464	Missense	central	0	yes	8.023	0.000	EPSD	COSMIC	7.780	Loss
AGC_Akt_AKT1_ST	P49815	TSC2	P31749	AKT1	S1464	S1464Y	1464	Missense	central	0	yes	8.023	0.000	EPSD	COSMIC	7.780	Loss
AGC_Akt_AKT1_ST	P49815	TSC2	P31749	AKT1	S1464	Y1461H	1461	Missense	distal	-3	no	8.023	10.914	EPSD	COSMIC	7.780	Up-regulation
AGC_Akt_AKT1_ST	P49815	TSC2	P31749	AKT1	S1464	R1459Q	1459	Missense	distal	-5	no	8.023	3.796	EPSD	COSMIC	7.780	Loss
AGC_Akt_AKT1_ST	P49815	TSC2	P31749	AKT1	S1464	I1463N	1463	Missense	proximal	-1	no	8.023	8.055	EPSD	COSMIC	7.780	Up-regulation
AGC_Akt_AKT1_ST	P49815	TSC2	P31749	AKT1	S1464	R1471M	1471	Missense	distal	7	no	8.023	7.957	EPSD	COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	P49815	TSC2	P31749	AKT1	S1464	R1470H	1470	Missense	distal	6	no	8.023	7.904	EPSD	COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	P49815	TSC2	P31749	AKT1	S1464	D1465N	1465	Missense	proximal	1	no	8.023	8.148	EPSD	COSMIC	7.780	Up-regulation
AGC_Akt_AKT1_ST	P49815	TSC2	P31749	AKT1	S1464	P1468T	1468	Missense	distal	4	no	8.023	7.862	EPSD	COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	P49815	TSC2	P31749	AKT1	S1464	T1462I	1462	Missense	proximal	-2	no	8.023	6.849	EPSD	COSMIC	7.780	Loss
AGC_Akt_AKT1_ST	P49815	TSC2	P31749	AKT1	S1464	S1464C	1464	Missense	central	0	yes	8.023	0.000	EPSD	COSMIC	7.780	Loss
AGC_Akt_AKT1_ST	P49815	TSC2	P31749	AKT1	S1798	R1795H	1795	Missense	distal	-3	no	18.057	13.358	EPSD	COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	P49815	TSC2	P31749	AKT1	S1798	R1793Q	1793	Missense	distal	-5	no	18.057	13.829	EPSD	COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	P49815	TSC2	P31749	AKT1	S1798	R1795C	1795	Missense	distal	-3	no	18.057	11.883	EPSD	COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	P49815	TSC2	P31749	AKT1	S1798	R1793W	1793	Missense	distal	-5	no	18.057	12.537	EPSD	COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	P49815	TSC2	P31749	AKT1	S1798	G1791S	1791	Missense	distal	-7	no	18.057	18.243	EPSD	COSMIC	7.780	Up-regulation
AGC_Akt_AKT1_ST	P49815	TSC2	P31749	AKT1	S1798	T1804I	1804	Missense	distal	6	no	18.057	17.872	EPSD	COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	P49815	TSC2	P31749	AKT1	S1798	R1793H	1793	Missense	distal	-5	no	18.057	14.962	EPSD	COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	P49815	TSC2	P31749	AKT1	S1798	R1793C	1793	Missense	distal	-5	no	18.057	13.980	EPSD	COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	P49815	TSC2	P31749	AKT1	S1799	R1795H	1795	Missense	distal	-4	no	8.617	7.558	EPSD	COSMIC	7.780	Loss
AGC_Akt_AKT1_ST	P49815	TSC2	P31749	AKT1	S1799	R1793Q	1793	Missense	distal	-6	no	8.617	8.533	EPSD	COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	P49815	TSC2	P31749	AKT1	S1799	R1795C	1795	Missense	distal	-4	no	8.617	6.938	EPSD	COSMIC	7.780	Loss
AGC_Akt_AKT1_ST	P49815	TSC2	P31749	AKT1	S1799	R1793W	1793	Missense	distal	-6	no	8.617	8.469	EPSD	COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	P49815	TSC2	P31749	AKT1	S1799	T1804I	1804	Missense	distal	5	no	8.617	8.520	EPSD	COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	P49815	TSC2	P31749	AKT1	S1799	F1806C	1806	Missense	distal	7	no	8.617	8.568	EPSD	COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	P49815	TSC2	P31749	AKT1	S1799	R1793H	1793	Missense	distal	-6	no	8.617	8.498	EPSD	COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	P49815	TSC2	P31749	AKT1	S1799	R1793C	1793	Missense	distal	-6	no	8.617	8.436	EPSD	COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	Q15633	TARBP2	P31749	AKT1	T179	Q182R	182	Missense	distal	3	no	8.679	8.735	EPSD	COSMIC	7.780	Up-regulation
AGC_Akt_AKT1_ST	Q15633	TARBP2	P31749	AKT1	T179	T179I	179	Missense	central	0	yes	8.679	0.000	EPSD	COSMIC;GDSC	7.780	Loss
AGC_Akt_AKT1_ST	Q15633	TARBP2	P31749	AKT1	S283	I276T	276	Missense	distal	-7	no	10.998	11.420	PhosphoSitePlus	COSMIC	7.780	Up-regulation
AGC_Akt_AKT1_ST	Q15633	TARBP2	P31749	AKT1	S283	S278Y	278	Missense	distal	-5	no	10.998	10.860	PhosphoSitePlus	COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	Q15633	TARBP2	P31749	AKT1	S283	L279I	279	Missense	distal	-4	no	10.998	10.740	PhosphoSitePlus	COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	P14618	PKM	P31749	AKT1	S6	A11V	11	Missense	distal	5	no	8.617	8.609	EPSD	COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	P14618	PKM	P31749	AKT1	S6	G9R	9	Missense	distal	3	no	8.617	8.692	EPSD	COSMIC	7.780	Up-regulation
AGC_Akt_AKT1_ST	P14618	PKM	P31749	AKT1	T10	A11V	11	Missense	proximal	1	no	8.264	8.336	EPSD	COSMIC	7.780	Up-regulation
AGC_Akt_AKT1_ST	P14618	PKM	P31749	AKT1	T10	G9R	9	Missense	proximal	-1	no	8.264	8.304	EPSD	COSMIC	7.780	Up-regulation
AGC_Akt_AKT1_ST	P14618	PKM	P31749	AKT1	T10	Q14H	14	Missense	distal	4	no	8.264	8.325	EPSD	COSMIC	7.780	Up-regulation
AGC_Akt_AKT1_ST	P14618	PKM	P31749	AKT1	S37	R32L	32	Missense	distal	-5	no	8.626	4.499	PhosphoSitePlus;EPSD	COSMIC	7.780	Loss
AGC_Akt_AKT1_ST	P14618	PKM	P31749	AKT1	T95	I88T	88	Missense	distal	-7	no	10.620	11.042	EPSD	COSMIC	7.780	Up-regulation
AGC_Akt_AKT1_ST	P14618	PKM	P31749	AKT1	T95	A94V	94	Missense	proximal	-1	no	10.620	10.605	EPSD	COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	P14618	PKM	P31749	AKT1	T95	P102L	102	Missense	distal	7	no	10.620	10.612	EPSD	COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	P14618	PKM	P31749	AKT1	S97	I103T	103	Missense	distal	6	no	11.366	11.551	EPSD;PhosphoSitePlus	COSMIC	7.780	Up-regulation
AGC_Akt_AKT1_ST	P14618	PKM	P31749	AKT1	S97	A94V	94	Missense	distal	-3	no	11.366	10.804	EPSD;PhosphoSitePlus	COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	P14618	PKM	P31749	AKT1	S97	P102L	102	Missense	distal	5	no	11.366	11.353	EPSD;PhosphoSitePlus	COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	P14618	PKM	P31749	AKT1	S249	F244L	244	Missense	distal	-5	no	11.640	11.036	EPSD	COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	P14618	PKM	P31749	AKT1	S249	E253D	253	Missense	distal	4	no	11.640	11.786	EPSD	COSMIC	7.780	Up-regulation
AGC_Akt_AKT1_ST	P14618	PKM	P31749	AKT1	S420	G415R	415	Missense	distal	-5	no	4.221	8.286	EPSD	COSMIC	7.780	Gain
AGC_Akt_AKT1_ST	P14618	PKM	P31749	AKT1	S519	P517H	517	Missense	proximal	-2	no	12.016	11.791	EPSD	COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	P14618	PKM	P31749	AKT1	S519	R526C	526	Missense	distal	7	no	12.016	11.886	EPSD	COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	P14618	PKM	P31749	AKT1	S519	R516H	516	Missense	distal	-3	no	12.016	7.317	EPSD	COSMIC	7.780	Loss
AGC_Akt_AKT1_ST	P02545	LMNA	P31749	AKT1	T10	G13A	13	Missense	distal	3	no	13.130	13.163	EPSD	COSMIC	7.780	Up-regulation
AGC_Akt_AKT1_ST	P02545	LMNA	P31749	AKT1	S12	G13A	13	Missense	proximal	1	no	12.055	12.286	EPSD	COSMIC	7.780	Up-regulation
AGC_Akt_AKT1_ST	P02545	LMNA	P31749	AKT1	S51	E55K	55	Missense	distal	4	no	8.659	8.558	EPSD	COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	P02545	LMNA	P31749	AKT1	S75	K78E	78	Missense	distal	3	no	11.162	11.118	EPSD	COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	P02545	LMNA	P31749	AKT1	S75	E73K	73	Missense	proximal	-2	no	11.162	11.821	EPSD	COSMIC	7.780	Up-regulation
AGC_Akt_AKT1_ST	P02545	LMNA	P31749	AKT1	S149	A147T	147	Missense	proximal	-2	no	8.537	8.923	EPSD	COSMIC	7.780	Up-regulation
AGC_Akt_AKT1_ST	P02545	LMNA	P31749	AKT1	S149	K155N	155	Missense	distal	6	no	8.537	8.459	EPSD	COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	P02545	LMNA	P31749	AKT1	S149	R156L	156	Missense	distal	7	no	8.537	8.463	EPSD	COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	P02545	LMNA	P31749	AKT1	T199	Q198K	198	Missense	proximal	-1	no	9.810	9.838	EPSD	COSMIC	7.780	Up-regulation
AGC_Akt_AKT1_ST	P02545	LMNA	P31749	AKT1	T199	L197M	197	Missense	proximal	-2	no	9.810	9.827	EPSD	COSMIC	7.780	Up-regulation
AGC_Akt_AKT1_ST	P02545	LMNA	P31749	AKT1	T224	N231D	231	Missense	distal	7	no	12.014	11.972	EPSD	COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	P02545	LMNA	P31749	AKT1	T224	V227M	227	Missense	distal	3	no	12.014	12.018	EPSD	COSMIC	7.780	Up-regulation
AGC_Akt_AKT1_ST	P02545	LMNA	P31749	AKT1	T224	R225Q	225	Missense	proximal	1	no	12.014	11.719	EPSD	COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	P02545	LMNA	P31749	AKT1	S268	L271P	271	Missense	distal	3	no	7.922	7.939	EPSD	COSMIC	7.780	Up-regulation
AGC_Akt_AKT1_ST	P02545	LMNA	P31749	AKT1	S268	L271R	271	Missense	distal	3	no	7.922	8.004	EPSD	COSMIC	7.780	Up-regulation
AGC_Akt_AKT1_ST	P02545	LMNA	P31749	AKT1	S268	Y267C	267	Missense	proximal	-1	no	7.922	7.888	EPSD	COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	P02545	LMNA	P31749	AKT1	S268	D272Y	272	Missense	distal	4	no	7.922	7.834	EPSD	COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	P02545	LMNA	P31749	AKT1	S268	A269V	269	Missense	proximal	1	no	7.922	7.995	EPSD	COSMIC	7.780	Up-regulation
AGC_Akt_AKT1_ST	P02545	LMNA	P31749	AKT1	S301	R298L	298	Missense	distal	-3	no	14.685	7.691	EPSD;PhosphoSitePlus	COSMIC	7.780	Loss
AGC_Akt_AKT1_ST	P02545	LMNA	P31749	AKT1	S301	R298C	298	Missense	distal	-3	no	14.685	8.511	EPSD;PhosphoSitePlus	COSMIC;GDSC;CCLE	7.780	Down-regulation
AGC_Akt_AKT1_ST	P02545	LMNA	P31749	AKT1	S301	R296C	296	Missense	distal	-5	no	14.685	10.608	EPSD;PhosphoSitePlus	COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	P02545	LMNA	P31749	AKT1	S303	R298L	298	Missense	distal	-5	no	9.098	4.972	EPSD	COSMIC	7.780	Loss
AGC_Akt_AKT1_ST	P02545	LMNA	P31749	AKT1	S303	R298C	298	Missense	distal	-5	no	9.098	5.021	EPSD	COSMIC;GDSC;CCLE	7.780	Loss
AGC_Akt_AKT1_ST	P02545	LMNA	P31749	AKT1	S303	Q310K	310	Missense	distal	7	no	9.098	9.147	EPSD	COSMIC	7.780	Up-regulation
AGC_Akt_AKT1_ST	P02545	LMNA	P31749	AKT1	S303	R296C	296	Missense	distal	-7	no	9.098	8.619	EPSD	COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	P02545	LMNA	P31749	AKT1	S326	D325N	325	Missense	proximal	-1	no	8.203	8.233	EPSD	COSMIC	7.780	Up-regulation
AGC_Akt_AKT1_ST	P02545	LMNA	P31749	AKT1	S392	L389R	389	Missense	distal	-3	no	5.502	12.496	EPSD	COSMIC	7.780	Gain
AGC_Akt_AKT1_ST	P02545	LMNA	P31749	AKT1	T394	L389R	389	Missense	distal	-5	no	6.198	10.325	EPSD	COSMIC	7.780	Gain
AGC_Akt_AKT1_ST	P02545	LMNA	P31749	AKT1	S404	S403F	403	Missense	proximal	-1	no	14.842	14.808	PhosphoSitePlus;EPSD	COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	P02545	LMNA	P31749	AKT1	S404	R401W	401	Missense	distal	-3	no	14.842	5.902	PhosphoSitePlus;EPSD	COSMIC	7.780	Loss
AGC_Akt_AKT1_ST	P02545	LMNA	P31749	AKT1	S406	S403F	403	Missense	distal	-3	no	7.840	10.022	EPSD	COSMIC	7.780	Up-regulation
AGC_Akt_AKT1_ST	P02545	LMNA	P31749	AKT1	S406	R401W	401	Missense	distal	-5	no	7.840	2.320	EPSD	COSMIC	7.780	Loss
AGC_Akt_AKT1_ST	P02545	LMNA	P31749	AKT1	S423	R427H	427	Missense	distal	4	no	9.391	9.576	EPSD	COSMIC;GDSC;CCLE	7.780	Up-regulation
AGC_Akt_AKT1_ST	P02545	LMNA	P31749	AKT1	S423	S428C	428	Missense	distal	5	no	9.391	9.273	EPSD	COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	P02545	LMNA	P31749	AKT1	S423	R419H	419	Missense	distal	-4	no	9.391	8.332	EPSD	COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	P02545	LMNA	P31749	AKT1	S423	E422G	422	Missense	proximal	-1	no	9.391	9.376	EPSD	COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	P02545	LMNA	P31749	AKT1	T424	R427H	427	Missense	distal	3	no	8.524	8.440	EPSD	COSMIC;GDSC;CCLE	7.780	Down-regulation
AGC_Akt_AKT1_ST	P02545	LMNA	P31749	AKT1	T424	S428C	428	Missense	distal	4	no	8.524	8.868	EPSD	COSMIC	7.780	Up-regulation
AGC_Akt_AKT1_ST	P02545	LMNA	P31749	AKT1	T424	R419H	419	Missense	distal	-5	no	8.524	5.429	EPSD	COSMIC	7.780	Loss
AGC_Akt_AKT1_ST	P02545	LMNA	P31749	AKT1	T424	E422G	422	Missense	proximal	-2	no	8.524	8.237	EPSD	COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	P02545	LMNA	P31749	AKT1	T548	D555Y	555	Missense	distal	7	no	11.111	11.145	EPSD	COSMIC	7.780	Up-regulation
AGC_Akt_AKT1_ST	P02545	LMNA	P31749	AKT1	T585	S583A	583	Missense	proximal	-2	no	8.795	8.343	EPSD	COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	P02545	LMNA	P31749	AKT1	T585	N580K	580	Missense	distal	-5	no	8.795	10.883	EPSD	COSMIC	7.780	Up-regulation
AGC_Akt_AKT1_ST	P02545	LMNA	P31749	AKT1	T585	C588W	588	Missense	distal	3	no	8.795	8.844	EPSD	COSMIC	7.780	Up-regulation
AGC_Akt_AKT1_ST	P02545	LMNA	P31749	AKT1	S632	G634V	634	Missense	proximal	2	no	9.330	9.124	EPSD	COSMIC;CCLE	7.780	Down-regulation
AGC_Akt_AKT1_ST	P02545	LMNA	P31749	AKT1	S632	S636I	636	Missense	distal	4	no	9.330	9.591	EPSD	COSMIC;CCLE	7.780	Up-regulation
AGC_Akt_AKT1_ST	P02545	LMNA	P31749	AKT1	S652	Q659L	659	Missense	distal	7	no	8.128	8.110	EPSD	COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	P02545	LMNA	P31749	AKT1	S652	R654Q	654	Missense	proximal	2	no	8.128	8.011	EPSD	COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	P02545	LMNA	P31749	AKT1	S657	I663M	663	Missense	distal	6	no	12.872	12.938	EPSD	COSMIC	7.780	Up-regulation
AGC_Akt_AKT1_ST	P02545	LMNA	P31749	AKT1	S657	Q659L	659	Missense	proximal	2	no	12.872	12.616	EPSD	COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	P02545	LMNA	P31749	AKT1	S657	R654Q	654	Missense	distal	-3	no	12.872	5.661	EPSD	COSMIC	7.780	Loss
AGC_Akt_AKT1_ST	P38398	BRCA1	P31749	AKT1	S76	R71G	71	Missense	distal	-5	no	10.091	6.027	EPSD	COSMIC	7.780	Loss
AGC_Akt_AKT1_ST	P38398	BRCA1	P31749	AKT1	S76	Q81E	81	Missense	distal	5	no	10.091	10.102	EPSD	COSMIC	7.780	Up-regulation
AGC_Akt_AKT1_ST	P38398	BRCA1	P31749	AKT1	S76	T77M	77	Missense	proximal	1	no	10.091	9.835	EPSD	COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	P38398	BRCA1	P31749	AKT1	S76	S76R	76	Missense	central	0	yes	10.091	0.000	EPSD	COSMIC	7.780	Loss
AGC_Akt_AKT1_ST	P38398	BRCA1	P31749	AKT1	S76	R71K	71	Missense	distal	-5	no	10.091	7.694	EPSD	COSMIC	7.780	Loss
AGC_Akt_AKT1_ST	P38398	BRCA1	P31749	AKT1	S76	Q81R	81	Missense	distal	5	no	10.091	10.142	EPSD	COSMIC	7.780	Up-regulation
AGC_Akt_AKT1_ST	P38398	BRCA1	P31749	AKT1	S76	S80N	80	Missense	distal	4	no	10.091	10.201	EPSD	COSMIC	7.780	Up-regulation
AGC_Akt_AKT1_ST	P38398	BRCA1	P31749	AKT1	S114	E111K	111	Missense	distal	-3	no	6.840	8.891	EPSD	COSMIC	7.780	Gain
AGC_Akt_AKT1_ST	P38398	BRCA1	P31749	AKT1	S335	C328Y	328	Missense	distal	-7	no	12.299	12.516	EPSD	COSMIC;GDSC;CCLE	7.780	Up-regulation
AGC_Akt_AKT1_ST	P38398	BRCA1	P31749	AKT1	S335	K338I	338	Missense	distal	3	no	12.299	12.166	EPSD	COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	P38398	BRCA1	P31749	AKT1	S335	P334S	334	Missense	proximal	-1	no	12.299	12.328	EPSD	COSMIC	7.780	Up-regulation
AGC_Akt_AKT1_ST	P38398	BRCA1	P31749	AKT1	S335	S335N	335	Missense	central	0	yes	12.299	0.000	EPSD	COSMIC	7.780	Loss
AGC_Akt_AKT1_ST	P38398	BRCA1	P31749	AKT1	S335	R332Q	332	Missense	distal	-3	no	12.299	5.088	EPSD	COSMIC	7.780	Loss
AGC_Akt_AKT1_ST	P38398	BRCA1	P31749	AKT1	S335	D330N	330	Missense	distal	-5	no	12.299	11.860	EPSD	COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	P38398	BRCA1	P31749	AKT1	S335	R332W	332	Missense	distal	-3	no	12.299	3.358	EPSD	COSMIC	7.780	Loss
AGC_Akt_AKT1_ST	P38398	BRCA1	P31749	AKT1	S335	R331G	331	Missense	distal	-4	no	12.299	11.484	EPSD	COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	P38398	BRCA1	P31749	AKT1	S335	S335I	335	Missense	central	0	yes	12.299	0.000	EPSD	COSMIC	7.780	Loss
AGC_Akt_AKT1_ST	P38398	BRCA1	P31749	AKT1	S335	E337V	337	Missense	proximal	2	no	12.299	11.950	EPSD	COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	P38398	BRCA1	P31749	AKT1	T336	K338I	338	Missense	proximal	2	no	7.874	7.201	EPSD	COSMIC	7.780	Loss
AGC_Akt_AKT1_ST	P38398	BRCA1	P31749	AKT1	T336	P334S	334	Missense	proximal	-2	no	7.874	8.698	EPSD	COSMIC	7.780	Up-regulation
AGC_Akt_AKT1_ST	P38398	BRCA1	P31749	AKT1	T336	S335N	335	Missense	proximal	-1	no	7.874	7.856	EPSD	COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	P38398	BRCA1	P31749	AKT1	T336	R332Q	332	Missense	distal	-4	no	7.874	7.253	EPSD	COSMIC	7.780	Loss
AGC_Akt_AKT1_ST	P38398	BRCA1	P31749	AKT1	T336	D330N	330	Missense	distal	-6	no	7.874	7.945	EPSD	COSMIC	7.780	Up-regulation
AGC_Akt_AKT1_ST	P38398	BRCA1	P31749	AKT1	T336	R332W	332	Missense	distal	-4	no	7.874	6.324	EPSD	COSMIC	7.780	Loss
AGC_Akt_AKT1_ST	P38398	BRCA1	P31749	AKT1	T336	R331G	331	Missense	distal	-5	no	7.874	3.809	EPSD	COSMIC	7.780	Loss
AGC_Akt_AKT1_ST	P38398	BRCA1	P31749	AKT1	T336	S335I	335	Missense	proximal	-1	no	7.874	7.824	EPSD	COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	P38398	BRCA1	P31749	AKT1	T336	E337V	337	Missense	proximal	1	no	7.874	7.968	EPSD	COSMIC	7.780	Up-regulation
AGC_Akt_AKT1_ST	P38398	BRCA1	P31749	AKT1	S449	H448R	448	Missense	proximal	-1	no	10.000	10.045	EPSD	COSMIC	7.780	Up-regulation
AGC_Akt_AKT1_ST	P38398	BRCA1	P31749	AKT1	S449	K443E	443	Missense	distal	-6	no	10.000	9.934	EPSD	COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	P38398	BRCA1	P31749	AKT1	S449	N455T	455	Missense	distal	6	no	10.000	10.088	EPSD	COSMIC	7.780	Up-regulation
AGC_Akt_AKT1_ST	P38398	BRCA1	P31749	AKT1	S449	I456T	456	Missense	distal	7	no	10.000	10.108	EPSD	COSMIC;GDSC;CCLE	7.780	Up-regulation
AGC_Akt_AKT1_ST	P38398	BRCA1	P31749	AKT1	S451	H448R	448	Missense	distal	-3	no	10.512	15.211	EPSD	COSMIC	7.780	Up-regulation
AGC_Akt_AKT1_ST	P38398	BRCA1	P31749	AKT1	S451	N455T	455	Missense	distal	4	no	10.512	10.398	EPSD	COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	P38398	BRCA1	P31749	AKT1	S451	I456T	456	Missense	distal	5	no	10.512	10.609	EPSD	COSMIC;GDSC;CCLE	7.780	Up-regulation
AGC_Akt_AKT1_ST	P38398	BRCA1	P31749	AKT1	T509	R506S	506	Missense	distal	-3	no	15.352	7.575	PhosphoSitePlus;EPSD	COSMIC	7.780	Loss
AGC_Akt_AKT1_ST	P38398	BRCA1	P31749	AKT1	T509	R504C	504	Missense	distal	-5	no	15.352	11.275	PhosphoSitePlus;EPSD	COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	P38398	BRCA1	P31749	AKT1	T509	S510L	510	Missense	proximal	1	no	15.352	15.450	PhosphoSitePlus;EPSD	COSMIC	7.780	Up-regulation
AGC_Akt_AKT1_ST	P38398	BRCA1	P31749	AKT1	T509	L512F	512	Missense	distal	3	no	15.352	15.351	PhosphoSitePlus;EPSD	COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	P38398	BRCA1	P31749	AKT1	T509	R507K	507	Missense	proximal	-2	no	15.352	15.791	PhosphoSitePlus;EPSD	COSMIC	7.780	Up-regulation
AGC_Akt_AKT1_ST	P38398	BRCA1	P31749	AKT1	T509	R507I	507	Missense	proximal	-2	no	15.352	14.299	PhosphoSitePlus;EPSD	COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	P38398	BRCA1	P31749	AKT1	S510	R506S	506	Missense	distal	-4	no	13.497	13.411	EPSD	COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	P38398	BRCA1	P31749	AKT1	S510	R504C	504	Missense	distal	-6	no	13.497	13.316	EPSD	COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	P38398	BRCA1	P31749	AKT1	S510	S510L	510	Missense	central	0	yes	13.497	0.000	EPSD	COSMIC	7.780	Loss
AGC_Akt_AKT1_ST	P38398	BRCA1	P31749	AKT1	S510	L512F	512	Missense	proximal	2	no	13.497	13.465	EPSD	COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	P38398	BRCA1	P31749	AKT1	S510	R507K	507	Missense	distal	-3	no	13.497	8.977	EPSD	COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	P38398	BRCA1	P31749	AKT1	S510	R507I	507	Missense	distal	-3	no	13.497	6.416	EPSD	COSMIC	7.780	Loss
AGC_Akt_AKT1_ST	P38398	BRCA1	P31749	AKT1	S615	H619N	619	Missense	distal	4	no	16.200	16.114	EPSD	COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	P38398	BRCA1	P31749	AKT1	S615	R613K	613	Missense	proximal	-2	no	16.200	16.639	EPSD	COSMIC	7.780	Up-regulation
AGC_Akt_AKT1_ST	P38398	BRCA1	P31749	AKT1	S615	K608N	608	Missense	distal	-7	no	16.200	16.043	EPSD	COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	P38398	BRCA1	P31749	AKT1	S615	R610S	610	Missense	distal	-5	no	16.200	11.729	EPSD	COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	P38398	BRCA1	P31749	AKT1	S615	S616N	616	Missense	proximal	1	no	16.200	16.111	EPSD	COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	P38398	BRCA1	P31749	AKT1	S616	H619N	619	Missense	distal	3	no	12.943	12.987	EPSD	COSMIC	7.780	Up-regulation
AGC_Akt_AKT1_ST	P38398	BRCA1	P31749	AKT1	S616	R613K	613	Missense	distal	-3	no	12.943	8.423	EPSD	COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	P38398	BRCA1	P31749	AKT1	S616	R610S	610	Missense	distal	-6	no	12.943	12.909	EPSD	COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	P38398	BRCA1	P31749	AKT1	S616	S616N	616	Missense	central	0	yes	12.943	0.000	EPSD	COSMIC	7.780	Loss
AGC_Akt_AKT1_ST	P38398	BRCA1	P31749	AKT1	T617	H619N	619	Missense	proximal	2	no	10.620	10.884	EPSD	COSMIC	7.780	Up-regulation
AGC_Akt_AKT1_ST	P38398	BRCA1	P31749	AKT1	T617	R613K	613	Missense	distal	-4	no	10.620	10.606	EPSD	COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	P38398	BRCA1	P31749	AKT1	T617	R610S	610	Missense	distal	-7	no	10.620	10.564	EPSD	COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	P38398	BRCA1	P31749	AKT1	T617	S616N	616	Missense	proximal	-1	no	10.620	10.602	EPSD	COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	P38398	BRCA1	P31749	AKT1	S632	N630H	630	Missense	proximal	-2	no	11.231	10.867	EPSD	COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	P38398	BRCA1	P31749	AKT1	S632	P633S	633	Missense	proximal	1	no	11.231	11.386	EPSD	COSMIC	7.780	Up-regulation
AGC_Akt_AKT1_ST	P38398	BRCA1	P31749	AKT1	S632	P634S	634	Missense	proximal	2	no	11.231	11.567	EPSD	COSMIC	7.780	Up-regulation
AGC_Akt_AKT1_ST	P38398	BRCA1	P31749	AKT1	S632	S628N	628	Missense	distal	-4	no	11.231	10.664	EPSD	COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	P38398	BRCA1	P31749	AKT1	S632	T637N	637	Missense	distal	5	no	11.231	11.196	EPSD	COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	P38398	BRCA1	P31749	AKT1	S632	E638D	638	Missense	distal	6	no	11.231	11.141	EPSD	COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	P38398	BRCA1	P31749	AKT1	S632	C636F	636	Missense	distal	4	no	11.231	11.082	EPSD	COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	P38398	BRCA1	P31749	AKT1	S632	P634R	634	Missense	proximal	2	no	11.231	11.395	EPSD	COSMIC	7.780	Up-regulation
AGC_Akt_AKT1_ST	P38398	BRCA1	P31749	AKT1	T637	P634R	634	Missense	distal	-3	no	3.203	9.843	EPSD	COSMIC	7.780	Gain
AGC_Akt_AKT1_ST	P38398	BRCA1	P31749	AKT1	S694	Q687P	687	Missense	distal	-7	no	11.050	10.994	EPSD;PhosphoSitePlus	COSMIC;GDSC;CCLE	7.780	Down-regulation
AGC_Akt_AKT1_ST	P38398	BRCA1	P31749	AKT1	S694	D693N	693	Missense	proximal	-1	no	11.050	11.080	EPSD;PhosphoSitePlus	COSMIC	7.780	Up-regulation
AGC_Akt_AKT1_ST	P38398	BRCA1	P31749	AKT1	S694	S694N	694	Missense	central	0	yes	11.050	0.000	EPSD;PhosphoSitePlus	COSMIC	7.780	Loss
AGC_Akt_AKT1_ST	P38398	BRCA1	P31749	AKT1	S694	R691I	691	Missense	distal	-3	no	11.050	3.969	EPSD;PhosphoSitePlus	COSMIC	7.780	Loss
AGC_Akt_AKT1_ST	P38398	BRCA1	P31749	AKT1	S694	D695N	695	Missense	proximal	1	no	11.050	11.174	EPSD;PhosphoSitePlus	COSMIC	7.780	Up-regulation
AGC_Akt_AKT1_ST	P38398	BRCA1	P31749	AKT1	S694	S694F	694	Missense	central	0	yes	11.050	0.000	EPSD;PhosphoSitePlus	COSMIC	7.780	Loss
AGC_Akt_AKT1_ST	P38398	BRCA1	P31749	AKT1	S694	S694Y	694	Missense	central	0	yes	11.050	0.000	EPSD;PhosphoSitePlus	COSMIC	7.780	Loss
AGC_Akt_AKT1_ST	P38398	BRCA1	P31749	AKT1	T696	D693N	693	Missense	distal	-3	no	9.561	8.035	EPSD	COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	P38398	BRCA1	P31749	AKT1	T696	S694N	694	Missense	proximal	-2	no	9.561	8.875	EPSD	COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	P38398	BRCA1	P31749	AKT1	T696	R691I	691	Missense	distal	-5	no	9.561	4.994	EPSD	COSMIC	7.780	Loss
AGC_Akt_AKT1_ST	P38398	BRCA1	P31749	AKT1	T696	D695N	695	Missense	proximal	-1	no	9.561	9.591	EPSD	COSMIC	7.780	Up-regulation
AGC_Akt_AKT1_ST	P38398	BRCA1	P31749	AKT1	T696	S694F	694	Missense	proximal	-2	no	9.561	8.694	EPSD	COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	P38398	BRCA1	P31749	AKT1	T696	S694Y	694	Missense	proximal	-2	no	9.561	8.639	EPSD	COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	P38398	BRCA1	P31749	AKT1	S767	S770L	770	Missense	distal	3	no	9.166	9.069	EPSD	COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	P38398	BRCA1	P31749	AKT1	S767	S763F	763	Missense	distal	-4	no	9.166	7.998	EPSD	COSMIC;GDSC;CCLE	7.780	Down-regulation
AGC_Akt_AKT1_ST	P38398	BRCA1	P31749	AKT1	S767	P773S	773	Missense	distal	6	no	9.166	9.260	EPSD	COSMIC	7.780	Up-regulation
AGC_Akt_AKT1_ST	P38398	BRCA1	P31749	AKT1	S767	E765K	765	Missense	proximal	-2	no	9.166	9.825	EPSD	COSMIC	7.780	Up-regulation
AGC_Akt_AKT1_ST	P38398	BRCA1	P31749	AKT1	S767	V772A	772	Missense	distal	5	no	9.166	9.175	EPSD	COSMIC;GDSC	7.780	Up-regulation
AGC_Akt_AKT1_ST	P38398	BRCA1	P31749	AKT1	S844	E842K	842	Missense	proximal	-2	no	12.608	13.267	EPSD	COSMIC	7.780	Up-regulation
AGC_Akt_AKT1_ST	P38398	BRCA1	P31749	AKT1	S844	R841W	841	Missense	distal	-3	no	12.608	3.667	EPSD	COSMIC	7.780	Loss
AGC_Akt_AKT1_ST	P38398	BRCA1	P31749	AKT1	S844	E849G	849	Missense	distal	5	no	12.608	12.577	EPSD	COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	P38398	BRCA1	P31749	AKT1	S844	T843A	843	Missense	proximal	-1	no	12.608	12.581	EPSD	COSMIC;GDSC;CCLE	7.780	Down-regulation
AGC_Akt_AKT1_ST	P38398	BRCA1	P31749	AKT1	S956	R951M	951	Missense	distal	-5	no	8.809	4.286	EPSD	COSMIC	7.780	Loss
AGC_Akt_AKT1_ST	P38398	BRCA1	P31749	AKT1	S956	E962K	962	Missense	distal	6	no	8.809	8.878	EPSD	COSMIC;GDSC;CCLE	7.780	Up-regulation
AGC_Akt_AKT1_ST	P38398	BRCA1	P31749	AKT1	S956	R951K	951	Missense	distal	-5	no	8.809	6.411	EPSD	COSMIC	7.780	Loss
AGC_Akt_AKT1_ST	P38398	BRCA1	P31749	AKT1	S956	C953Y	953	Missense	distal	-3	no	8.809	7.393	EPSD	COSMIC	7.780	Loss
AGC_Akt_AKT1_ST	P38398	BRCA1	P31749	AKT1	S1191	E1185Q	1185	Missense	distal	-6	no	11.771	11.767	EPSD	COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	P38398	BRCA1	P31749	AKT1	S1191	P1190H	1190	Missense	proximal	-1	no	11.771	11.766	EPSD	COSMIC;GDSC;CCLE	7.780	Down-regulation
AGC_Akt_AKT1_ST	P38398	BRCA1	P31749	AKT1	S1191	P1190F	1190	Missense	proximal	-1	no	11.771	11.765	EPSD	COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	P38398	BRCA1	P31749	AKT1	S1191	P1192F	1192	Missense	proximal	1	no	11.771	11.944	EPSD	COSMIC	7.780	Up-regulation
AGC_Akt_AKT1_ST	P38398	BRCA1	P31749	AKT1	S1191	P1190L	1190	Missense	proximal	-1	no	11.771	11.772	EPSD	COSMIC	7.780	Up-regulation
AGC_Akt_AKT1_ST	P38398	BRCA1	P31749	AKT1	S1191	P1192S	1192	Missense	proximal	1	no	11.771	11.926	EPSD	COSMIC	7.780	Up-regulation
AGC_Akt_AKT1_ST	P38398	BRCA1	P31749	AKT1	S1191	P1192L	1192	Missense	proximal	1	no	11.771	12.025	EPSD	COSMIC	7.780	Up-regulation
AGC_Akt_AKT1_ST	P38398	BRCA1	P31749	AKT1	S1191	R1188K	1188	Missense	distal	-3	no	11.771	7.251	EPSD	COSMIC	7.780	Loss
AGC_Akt_AKT1_ST	P38398	BRCA1	P31749	AKT1	S1191	H1197Y	1197	Missense	distal	6	no	11.771	11.803	EPSD	COSMIC	7.780	Up-regulation
AGC_Akt_AKT1_ST	P38398	BRCA1	P31749	AKT1	S1211	E1214K	1214	Missense	distal	3	no	9.013	9.057	EPSD	COSMIC	7.780	Up-regulation
AGC_Akt_AKT1_ST	P38398	BRCA1	P31749	AKT1	S1211	K1208T	1208	Missense	distal	-3	no	9.013	6.512	EPSD	COSMIC	7.780	Loss
AGC_Akt_AKT1_ST	P38398	BRCA1	P31749	AKT1	S1211	S1212P	1212	Missense	proximal	1	no	9.013	8.858	EPSD	COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	P38398	BRCA1	P31749	AKT1	S1211	R1204K	1204	Missense	distal	-7	no	9.013	9.000	EPSD	COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	P38398	BRCA1	P31749	AKT1	S1211	E1210K	1210	Missense	proximal	-1	no	9.013	9.034	EPSD	COSMIC	7.780	Up-regulation
AGC_Akt_AKT1_ST	P38398	BRCA1	P31749	AKT1	S1211	K1207T	1207	Missense	distal	-4	no	9.013	8.997	EPSD	COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	P38398	BRCA1	P31749	AKT1	T1246	Q1240E	1240	Missense	distal	-6	no	11.072	11.075	EPSD	COSMIC	7.780	Up-regulation
AGC_Akt_AKT1_ST	P38398	BRCA1	P31749	AKT1	T1246	S1245N	1245	Missense	proximal	-1	no	11.072	11.054	EPSD	COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	P38398	BRCA1	P31749	AKT1	T1246	H1244Y	1244	Missense	proximal	-2	no	11.072	11.199	EPSD	COSMIC	7.780	Up-regulation
AGC_Akt_AKT1_ST	P38398	BRCA1	P31749	AKT1	T1246	Q1240L	1240	Missense	distal	-6	no	11.072	11.071	EPSD	COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	P38398	BRCA1	P31749	AKT1	T1246	L1252Q	1252	Missense	distal	6	no	11.072	11.103	EPSD	COSMIC	7.780	Up-regulation
AGC_Akt_AKT1_ST	P38398	BRCA1	P31749	AKT1	T1246	S1241F	1241	Missense	distal	-5	no	11.072	12.020	EPSD	COSMIC	7.780	Up-regulation
AGC_Akt_AKT1_ST	P38398	BRCA1	P31749	AKT1	T1246	T1246A	1246	Missense	central	0	yes	11.072	0.000	EPSD	COSMIC	7.780	Loss
AGC_Akt_AKT1_ST	P38398	BRCA1	P31749	AKT1	T1246	T1249P	1249	Missense	distal	3	no	11.072	10.991	EPSD	COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	P38398	BRCA1	P31749	AKT1	T1246	S1245Y	1245	Missense	proximal	-1	no	11.072	11.046	EPSD	COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	P38398	BRCA1	P31749	AKT1	T1246	S1245A	1245	Missense	proximal	-1	no	11.072	11.051	EPSD	COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	P38398	BRCA1	P31749	AKT1	T1246	S1239T	1239	Missense	distal	-7	no	11.072	11.122	EPSD	COSMIC	7.780	Up-regulation
AGC_Akt_AKT1_ST	P38398	BRCA1	P31749	AKT1	T1246	S1245F	1245	Missense	proximal	-1	no	11.072	11.037	EPSD	COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	P38398	BRCA1	P31749	AKT1	S1328	G1332R	1332	Missense	distal	4	no	12.039	11.876	EPSD	COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	P38398	BRCA1	P31749	AKT1	S1330	G1332R	1332	Missense	proximal	2	no	8.174	8.334	EPSD	COSMIC	7.780	Up-regulation
AGC_Akt_AKT1_ST	P38398	BRCA1	P31749	AKT1	S1516	S1512I	1512	Missense	distal	-4	no	8.392	7.010	EPSD	COSMIC	7.780	Loss
AGC_Akt_AKT1_ST	P38398	BRCA1	P31749	AKT1	S1516	N1519S	1519	Missense	distal	3	no	8.392	8.448	EPSD	COSMIC	7.780	Up-regulation
AGC_Akt_AKT1_ST	P38398	BRCA1	P31749	AKT1	S1516	G1515E	1515	Missense	proximal	-1	no	8.392	8.407	EPSD	COSMIC	7.780	Up-regulation
AGC_Akt_AKT1_ST	P38398	BRCA1	P31749	AKT1	S1516	L1517V	1517	Missense	proximal	1	no	8.392	8.292	EPSD	COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	P38398	BRCA1	P31749	AKT1	S1516	L1517P	1517	Missense	proximal	1	no	8.392	8.138	EPSD	COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	P38398	BRCA1	P31749	AKT1	S1516	P1523L	1523	Missense	distal	7	no	8.392	8.384	EPSD	COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	P38398	BRCA1	P31749	AKT1	T1675	A1669S	1669	Missense	distal	-6	no	11.680	11.735	EPSD	COSMIC	7.780	Up-regulation
AGC_Akt_AKT1_ST	P38398	BRCA1	P31749	AKT1	T1675	L1676F	1676	Missense	proximal	1	no	11.680	11.599	EPSD	COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	P38398	BRCA1	P31749	AKT1	T1675	T1675A	1675	Missense	central	0	yes	11.680	0.000	EPSD	COSMIC	7.780	Loss
AGC_Akt_AKT1_ST	P38398	BRCA1	P31749	AKT1	T1675	I1680V	1680	Missense	distal	5	no	11.680	11.717	EPSD	COSMIC	7.780	Up-regulation
AGC_Akt_AKT1_ST	P38398	BRCA1	P31749	AKT1	T1675	E1682K	1682	Missense	distal	7	no	11.680	11.714	EPSD	COSMIC	7.780	Up-regulation
AGC_Akt_AKT1_ST	P38398	BRCA1	P31749	AKT1	T1675	I1674F	1674	Missense	proximal	-1	no	11.680	11.695	EPSD	COSMIC	7.780	Up-regulation
AGC_Akt_AKT1_ST	P38398	BRCA1	P31749	AKT1	T1675	R1670K	1670	Missense	distal	-5	no	11.680	9.283	EPSD	COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	P38398	BRCA1	P31749	AKT1	T1675	R1670I	1670	Missense	distal	-5	no	11.680	7.113	EPSD	COSMIC	7.780	Loss
AGC_Akt_AKT1_ST	P38398	BRCA1	P31749	AKT1	T1700	C1697R	1697	Missense	distal	-3	no	3.732	9.906	EPSD	COSMIC	7.780	Gain
AGC_Akt_AKT1_ST	Q16584	MAP3K11	P31749	AKT1	T503	H500R	500	Missense	distal	-3	no	6.142	10.841	EPSD	COSMIC	7.780	Gain
AGC_Akt_AKT1_ST	Q16584	MAP3K11	P31749	AKT1	S674	T680M	680	Missense	distal	6	no	16.907	16.787	PhosphoSitePlus	COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	Q16584	MAP3K11	P31749	AKT1	S674	G672R	672	Missense	proximal	-2	no	16.907	17.413	PhosphoSitePlus	COSMIC	7.780	Up-regulation
AGC_Akt_AKT1_ST	Q16584	MAP3K11	P31749	AKT1	S674	R671H	671	Missense	distal	-3	no	16.907	12.208	PhosphoSitePlus	COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	Q16584	MAP3K11	P31749	AKT1	S674	P679L	679	Missense	distal	5	no	16.907	16.893	PhosphoSitePlus	COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	Q16584	MAP3K11	P31749	AKT1	S674	P667S	667	Missense	distal	-7	no	16.907	17.101	PhosphoSitePlus	COSMIC	7.780	Up-regulation
AGC_Akt_AKT1_ST	Q16584	MAP3K11	P31749	AKT1	S724	P719R	719	Missense	distal	-5	no	4.120	8.131	EPSD	COSMIC	7.780	Gain
AGC_Akt_AKT1_ST	Q16584	MAP3K11	P31749	AKT1	T738	R735C	735	Missense	distal	-3	no	11.934	5.760	EPSD	COSMIC;GDSC	7.780	Loss
AGC_Akt_AKT1_ST	Q16584	MAP3K11	P31749	AKT1	T738	R735S	735	Missense	distal	-3	no	11.934	4.157	EPSD	COSMIC	7.780	Loss
AGC_Akt_AKT1_ST	Q16584	MAP3K11	P31749	AKT1	S740	R735C	735	Missense	distal	-5	no	9.218	5.141	EPSD	COSMIC;GDSC	7.780	Loss
AGC_Akt_AKT1_ST	Q16584	MAP3K11	P31749	AKT1	S740	R735S	735	Missense	distal	-5	no	9.218	4.748	EPSD	COSMIC	7.780	Loss
AGC_Akt_AKT1_ST	Q16584	MAP3K11	P31749	AKT1	T752	P750S	750	Missense	proximal	-2	no	8.094	8.919	EPSD	COSMIC	7.780	Up-regulation
AGC_Akt_AKT1_ST	Q16584	MAP3K11	P31749	AKT1	S780	P786S	786	Missense	distal	6	no	8.768	8.861	EPSD	COSMIC	7.780	Up-regulation
AGC_Akt_AKT1_ST	Q16584	MAP3K11	P31749	AKT1	S780	R773H	773	Missense	distal	-7	no	8.768	8.466	EPSD	COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	P55211	CASP9	P31749	AKT1	T125	T125P	125	Missense	central	0	yes	10.550	0.000	EPSD	COSMIC	7.780	Loss
AGC_Akt_AKT1_ST	P55211	CASP9	P31749	AKT1	T181	S183F	183	Missense	proximal	2	no	11.872	11.295	EPSD	COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	P55211	CASP9	P31749	AKT1	S183	S183F	183	Missense	central	0	yes	17.682	0.000	EPSD	COSMIC	7.780	Loss
AGC_Akt_AKT1_ST	P55211	CASP9	P31749	AKT1	S195	R192H	192	Missense	distal	-3	no	12.401	7.702	EPSD	COSMIC	7.780	Loss
AGC_Akt_AKT1_ST	P55211	CASP9	P31749	AKT1	S195	R193C	193	Missense	proximal	-2	no	12.401	10.936	EPSD	COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	P55211	CASP9	P31749	AKT1	S195	S196Y	196	Missense	proximal	1	no	12.401	12.393	EPSD	COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	P55211	CASP9	P31749	AKT1	S196	R192H	192	Missense	distal	-4	no	15.219	14.160	PhosphoSitePlus	COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	P55211	CASP9	P31749	AKT1	S196	R193C	193	Missense	distal	-3	no	15.219	9.046	PhosphoSitePlus	COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	P55211	CASP9	P31749	AKT1	S196	S196Y	196	Missense	central	0	yes	15.219	0.000	PhosphoSitePlus	COSMIC	7.780	Loss
AGC_Akt_AKT1_ST	O60343	TBC1D4	P31749	AKT1	S66	Q67R	67	Missense	proximal	1	no	11.471	11.766	EPSD	COSMIC	7.780	Up-regulation
AGC_Akt_AKT1_ST	O60343	TBC1D4	P31749	AKT1	S66	G73D	73	Missense	distal	7	no	11.471	11.467	EPSD	COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	O60343	TBC1D4	P31749	AKT1	S66	E70K	70	Missense	distal	4	no	11.471	11.370	EPSD	COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	O60343	TBC1D4	P31749	AKT1	S66	G73S	73	Missense	distal	7	no	11.471	11.544	EPSD	COSMIC	7.780	Up-regulation
AGC_Akt_AKT1_ST	O60343	TBC1D4	P31749	AKT1	S304	E302K	302	Missense	proximal	-2	no	7.249	7.909	EPSD	COSMIC	7.780	Gain
AGC_Akt_AKT1_ST	O60343	TBC1D4	P31749	AKT1	S318	G321S	321	Missense	distal	3	no	15.833	15.924	PhosphoSitePlus;EPSD	COSMIC;GDSC	7.780	Up-regulation
AGC_Akt_AKT1_ST	O60343	TBC1D4	P31749	AKT1	S318	R324W	324	Missense	distal	6	no	15.833	15.675	PhosphoSitePlus;EPSD	COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	O60343	TBC1D4	P31749	AKT1	S330	P335L	335	Missense	distal	5	no	10.553	10.540	EPSD	COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	O60343	TBC1D4	P31749	AKT1	S330	R324W	324	Missense	distal	-6	no	10.553	10.406	EPSD	COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	O60343	TBC1D4	P31749	AKT1	S330	H327Y	327	Missense	distal	-3	no	10.553	7.663	EPSD	COSMIC	7.780	Loss
AGC_Akt_AKT1_ST	O60343	TBC1D4	P31749	AKT1	S341	P335L	335	Missense	distal	-6	no	16.535	16.549	EPSD;PhosphoSitePlus	COSMIC	7.780	Up-regulation
AGC_Akt_AKT1_ST	O60343	TBC1D4	P31749	AKT1	S341	S344C	344	Missense	distal	3	no	16.535	16.358	EPSD;PhosphoSitePlus	COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	O60343	TBC1D4	P31749	AKT1	S485	Q481H	481	Missense	distal	-4	no	9.754	9.316	EPSD	COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	O60343	TBC1D4	P31749	AKT1	S486	Q481H	481	Missense	distal	-5	no	6.737	7.870	EPSD	COSMIC	7.780	Gain
AGC_Akt_AKT1_ST	O60343	TBC1D4	P31749	AKT1	S570	R577M	577	Missense	distal	7	no	9.973	9.906	EPSD;PhosphoSitePlus	COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	O60343	TBC1D4	P31749	AKT1	S621	P618R	618	Missense	distal	-3	no	4.206	10.846	EPSD	COSMIC	7.780	Gain
AGC_Akt_AKT1_ST	O60343	TBC1D4	P31749	AKT1	S751	L758I	758	Missense	distal	7	no	16.107	16.076	EPSD;PhosphoSitePlus	COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	O60343	TBC1D4	P31749	AKT1	S771	R773Q	773	Missense	proximal	2	no	11.807	11.690	EPSD	COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	O60343	TBC1D4	P31749	AKT1	S771	R775H	775	Missense	distal	4	no	11.807	11.992	EPSD	COSMIC	7.780	Up-regulation
AGC_Akt_AKT1_ST	O60343	TBC1D4	P31749	AKT1	S782	S787A	787	Missense	distal	5	no	11.626	11.575	EPSD	COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	O60343	TBC1D4	P31749	AKT1	S782	A781D	781	Missense	proximal	-1	no	11.626	11.599	EPSD	COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	O60343	TBC1D4	P31749	AKT1	S782	P783A	783	Missense	proximal	1	no	11.626	11.708	EPSD	COSMIC	7.780	Up-regulation
AGC_Akt_AKT1_ST	O60343	TBC1D4	P31749	AKT1	S782	R775H	775	Missense	distal	-7	no	11.626	11.325	EPSD	COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	O60343	TBC1D4	P31749	AKT1	S872	S872F	872	Missense	central	0	yes	8.588	0.000	EPSD	COSMIC	7.780	Loss
AGC_Akt_AKT1_ST	O60343	TBC1D4	P31749	AKT1	S1050	Q1052H	1052	Missense	proximal	2	no	10.165	9.922	EPSD	COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	O60343	TBC1D4	P31749	AKT1	S1050	I1053M	1053	Missense	distal	3	no	10.165	10.211	EPSD	COSMIC	7.780	Up-regulation
AGC_Akt_AKT1_ST	O60343	TBC1D4	P31749	AKT1	S1126	L1123R	1123	Missense	distal	-3	no	5.145	12.139	EPSD	COSMIC;GDSC;CCLE	7.780	Gain
AGC_Akt_AKT1_ST	O60343	TBC1D4	P31749	AKT1	S1126	L1121R	1121	Missense	distal	-5	no	5.145	9.271	EPSD	COSMIC	7.780	Gain
AGC_Akt_AKT1_ST	O60343	TBC1D4	P31749	AKT1	S1207	A1205T	1205	Missense	proximal	-2	no	10.377	10.763	EPSD	COSMIC	7.780	Up-regulation
AGC_Akt_AKT1_ST	Q2PPJ7	RALGAPA2	P31749	AKT1	S364	R370Q	370	Missense	distal	6	no	9.946	9.875	EPSD	COSMIC;GDSC;CCLE	7.780	Down-regulation
AGC_Akt_AKT1_ST	Q2PPJ7	RALGAPA2	P31749	AKT1	S373	R370Q	370	Missense	distal	-3	no	11.748	4.537	EPSD	COSMIC;GDSC;CCLE	7.780	Loss
AGC_Akt_AKT1_ST	Q2PPJ7	RALGAPA2	P31749	AKT1	S373	L372R	372	Missense	proximal	-1	no	11.748	11.787	EPSD	COSMIC	7.780	Up-regulation
AGC_Akt_AKT1_ST	Q2PPJ7	RALGAPA2	P31749	AKT1	S375	R370Q	370	Missense	distal	-5	no	9.734	5.507	EPSD	COSMIC;GDSC;CCLE	7.780	Loss
AGC_Akt_AKT1_ST	Q2PPJ7	RALGAPA2	P31749	AKT1	S375	L372R	372	Missense	distal	-3	no	9.734	16.728	EPSD	COSMIC	7.780	Up-regulation
AGC_Akt_AKT1_ST	Q2PPJ7	RALGAPA2	P31749	AKT1	S376	L372R	372	Missense	distal	-4	no	6.619	7.829	EPSD	COSMIC	7.780	Gain
AGC_Akt_AKT1_ST	Q2PPJ7	RALGAPA2	P31749	AKT1	S478	R483H	483	Missense	distal	5	no	8.596	8.522	EPSD	COSMIC;GDSC;CCLE	7.780	Down-regulation
AGC_Akt_AKT1_ST	Q2PPJ7	RALGAPA2	P31749	AKT1	S478	R477Q	477	Missense	proximal	-1	no	8.596	8.564	EPSD	COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	Q2PPJ7	RALGAPA2	P31749	AKT1	S479	R483H	483	Missense	distal	4	no	7.731	7.915	EPSD	COSMIC;GDSC;CCLE	7.780	Gain
AGC_Akt_AKT1_ST	Q2PPJ7	RALGAPA2	P31749	AKT1	S480	R483H	483	Missense	distal	3	no	13.486	13.402	EPSD	COSMIC;GDSC;CCLE	7.780	Down-regulation
AGC_Akt_AKT1_ST	Q2PPJ7	RALGAPA2	P31749	AKT1	S480	R477Q	477	Missense	distal	-3	no	13.486	6.275	EPSD	COSMIC	7.780	Loss
AGC_Akt_AKT1_ST	Q2PPJ7	RALGAPA2	P31749	AKT1	S486	R483H	483	Missense	distal	-3	no	9.893	5.194	EPSD;PhosphoSitePlus	COSMIC;GDSC;CCLE	7.780	Loss
AGC_Akt_AKT1_ST	Q2PPJ7	RALGAPA2	P31749	AKT1	S766	R763W	763	Missense	distal	-3	no	11.428	2.488	EPSD	COSMIC	7.780	Loss
AGC_Akt_AKT1_ST	Q2PPJ7	RALGAPA2	P31749	AKT1	S768	R763W	763	Missense	distal	-5	no	8.956	3.436	EPSD	COSMIC	7.780	Loss
AGC_Akt_AKT1_ST	Q2PPJ7	RALGAPA2	P31749	AKT1	S820	L827F	827	Missense	distal	7	no	9.942	9.935	EPSD	COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	Q2PPJ7	RALGAPA2	P31749	AKT1	S821	L827F	827	Missense	distal	6	no	11.519	11.503	EPSD	COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	Q2PPJ7	RALGAPA2	P31749	AKT1	S844	S844N	844	Missense	central	0	yes	16.116	0.000	EPSD	COSMIC	7.780	Loss
AGC_Akt_AKT1_ST	Q2PPJ7	RALGAPA2	P31749	AKT1	S846	S844N	844	Missense	proximal	-2	no	11.253	10.567	EPSD	COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	Q2PPJ7	RALGAPA2	P31749	AKT1	S1467	D1465E	1465	Missense	proximal	-2	no	9.698	10.683	EPSD	COSMIC	7.780	Up-regulation
AGC_Akt_AKT1_ST	Q2PPJ7	RALGAPA2	P31749	AKT1	S1467	R1464S	1464	Missense	distal	-3	no	9.698	1.922	EPSD	COSMIC	7.780	Loss
AGC_Akt_AKT1_ST	Q2PPJ7	RALGAPA2	P31749	AKT1	S1493	H1500R	1500	Missense	distal	7	no	10.565	10.636	EPSD	COSMIC	7.780	Up-regulation
AGC_Akt_AKT1_ST	Q2PPJ7	RALGAPA2	P31749	AKT1	S1493	N1488S	1488	Missense	distal	-5	no	10.565	10.579	EPSD	COSMIC	7.780	Up-regulation
AGC_Akt_AKT1_ST	Q2PPJ7	RALGAPA2	P31749	AKT1	T1646	E1645K	1645	Missense	proximal	-1	no	8.788	8.809	EPSD	COSMIC	7.780	Up-regulation
AGC_Akt_AKT1_ST	Q2PPJ7	RALGAPA2	P31749	AKT1	T1646	V1651L	1651	Missense	distal	5	no	8.788	8.781	EPSD	COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	Q2PPJ7	RALGAPA2	P31749	AKT1	T1646	A1650S	1650	Missense	distal	4	no	8.788	8.664	EPSD	COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	Q3V6T2	CCDC88A	P31749	AKT1	S245	H248Y	248	Missense	distal	3	no	11.676	11.707	EPSD	COSMIC	7.780	Up-regulation
AGC_Akt_AKT1_ST	Q3V6T2	CCDC88A	P31749	AKT1	S245	S250L	250	Missense	distal	5	no	11.676	11.609	EPSD	COSMIC;GDSC;CCLE	7.780	Down-regulation
AGC_Akt_AKT1_ST	Q3V6T2	CCDC88A	P31749	AKT1	S245	R242Q	242	Missense	distal	-3	no	11.676	4.465	EPSD	COSMIC	7.780	Loss
AGC_Akt_AKT1_ST	Q3V6T2	CCDC88A	P31749	AKT1	S245	R246T	246	Missense	proximal	1	no	11.676	11.724	EPSD	COSMIC	7.780	Up-regulation
AGC_Akt_AKT1_ST	Q3V6T2	CCDC88A	P31749	AKT1	S775	N774K	774	Missense	proximal	-1	no	8.329	8.354	EPSD	COSMIC	7.780	Up-regulation
AGC_Akt_AKT1_ST	Q3V6T2	CCDC88A	P31749	AKT1	S775	I779V	779	Missense	distal	4	no	8.329	8.248	EPSD	COSMIC;GDSC;CCLE	7.780	Down-regulation
AGC_Akt_AKT1_ST	Q3V6T2	CCDC88A	P31749	AKT1	S913	R908H	908	Missense	distal	-5	no	8.703	5.609	EPSD	COSMIC;CCLE	7.780	Loss
AGC_Akt_AKT1_ST	Q3V6T2	CCDC88A	P31749	AKT1	S1151	L1152F	1152	Missense	proximal	1	no	8.348	8.267	EPSD	COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	Q3V6T2	CCDC88A	P31749	AKT1	S1151	S1151F	1151	Missense	central	0	yes	8.348	0.000	EPSD	COSMIC	7.780	Loss
AGC_Akt_AKT1_ST	Q3V6T2	CCDC88A	P31749	AKT1	S1151	D1148N	1148	Missense	distal	-3	no	8.348	6.822	EPSD	COSMIC	7.780	Loss
AGC_Akt_AKT1_ST	Q3V6T2	CCDC88A	P31749	AKT1	S1151	E1145V	1145	Missense	distal	-6	no	8.348	8.319	EPSD	COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	Q3V6T2	CCDC88A	P31749	AKT1	S1151	K1158E	1158	Missense	distal	7	no	8.348	8.315	EPSD	COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	Q3V6T2	CCDC88A	P31749	AKT1	S1417	R1414H	1414	Missense	distal	-3	no	15.901	11.202	PhosphoSitePlus	COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	Q3V6T2	CCDC88A	P31749	AKT1	S1417	R1414C	1414	Missense	distal	-3	no	15.901	9.727	PhosphoSitePlus	COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	Q3V6T2	CCDC88A	P31749	AKT1	S1417	R1412W	1412	Missense	distal	-5	no	15.901	10.381	PhosphoSitePlus	COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	Q3V6T2	CCDC88A	P31749	AKT1	S1417	R1412L	1412	Missense	distal	-5	no	15.901	11.775	PhosphoSitePlus	COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	Q3V6T2	CCDC88A	P31749	AKT1	T1419	R1414H	1414	Missense	distal	-5	no	12.092	8.997	EPSD	COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	Q3V6T2	CCDC88A	P31749	AKT1	T1419	R1414C	1414	Missense	distal	-5	no	12.092	8.015	EPSD	COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	Q3V6T2	CCDC88A	P31749	AKT1	T1419	R1412W	1412	Missense	distal	-7	no	12.092	11.668	EPSD	COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	Q3V6T2	CCDC88A	P31749	AKT1	T1419	R1412L	1412	Missense	distal	-7	no	12.092	11.802	EPSD	COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	Q3V6T2	CCDC88A	P31749	AKT1	S1427	F1431C	1431	Missense	distal	4	no	12.029	12.178	EPSD	COSMIC;CCLE	7.780	Up-regulation
AGC_Akt_AKT1_ST	Q3V6T2	CCDC88A	P31749	AKT1	S1462	K1459N	1459	Missense	distal	-3	no	8.042	5.086	EPSD	COSMIC	7.780	Loss
AGC_Akt_AKT1_ST	Q3V6T2	CCDC88A	P31749	AKT1	S1462	K1459Q	1459	Missense	distal	-3	no	8.042	5.351	EPSD	COSMIC	7.780	Loss
AGC_Akt_AKT1_ST	Q3V6T2	CCDC88A	P31749	AKT1	S1491	S1489F	1489	Missense	proximal	-2	no	10.933	10.066	EPSD	COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	Q3V6T2	CCDC88A	P31749	AKT1	S1491	R1487C	1487	Missense	distal	-4	no	10.933	9.254	EPSD	COSMIC;GDSC	7.780	Down-regulation
AGC_Akt_AKT1_ST	Q3V6T2	CCDC88A	P31749	AKT1	S1491	D1494N	1494	Missense	distal	3	no	10.933	10.988	EPSD	COSMIC;CCLE	7.780	Up-regulation
AGC_Akt_AKT1_ST	Q3V6T2	CCDC88A	P31749	AKT1	S1587	R1592T	1592	Missense	distal	5	no	12.246	12.239	EPSD	COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	Q3V6T2	CCDC88A	P31749	AKT1	S1587	V1580A	1580	Missense	distal	-7	no	12.246	12.374	EPSD	COSMIC	7.780	Up-regulation
AGC_Akt_AKT1_ST	Q3V6T2	CCDC88A	P31749	AKT1	S1587	A1586T	1586	Missense	proximal	-1	no	12.246	12.273	EPSD	COSMIC	7.780	Up-regulation
AGC_Akt_AKT1_ST	Q3V6T2	CCDC88A	P31749	AKT1	S1587	G1591A	1591	Missense	distal	4	no	12.246	12.196	EPSD	COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	Q3V6T2	CCDC88A	P31749	AKT1	T1595	S1598Y	1598	Missense	distal	3	no	9.982	9.913	EPSD	COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	Q3V6T2	CCDC88A	P31749	AKT1	T1595	R1592T	1592	Missense	distal	-3	no	9.982	2.960	EPSD	COSMIC	7.780	Loss
AGC_Akt_AKT1_ST	Q3V6T2	CCDC88A	P31749	AKT1	T1595	T1595A	1595	Missense	central	0	yes	9.982	0.000	EPSD	COSMIC	7.780	Loss
AGC_Akt_AKT1_ST	Q3V6T2	CCDC88A	P31749	AKT1	T1595	S1598N	1598	Missense	distal	3	no	9.982	9.925	EPSD	COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	Q3V6T2	CCDC88A	P31749	AKT1	T1595	G1591A	1591	Missense	distal	-4	no	9.982	9.989	EPSD	COSMIC	7.780	Up-regulation
AGC_Akt_AKT1_ST	Q3V6T2	CCDC88A	P31749	AKT1	T1595	S1598G	1598	Missense	distal	3	no	9.982	9.891	EPSD	COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	Q3V6T2	CCDC88A	P31749	AKT1	S1653	I1660M	1660	Missense	distal	7	no	9.881	9.920	EPSD	COSMIC	7.780	Up-regulation
AGC_Akt_AKT1_ST	Q3V6T2	CCDC88A	P31749	AKT1	S1653	R1651T	1651	Missense	proximal	-2	no	9.881	10.003	EPSD	COSMIC	7.780	Up-regulation
AGC_Akt_AKT1_ST	Q3V6T2	CCDC88A	P31749	AKT1	S1653	L1656F	1656	Missense	distal	3	no	9.881	9.880	EPSD	COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	Q3V6T2	CCDC88A	P31749	AKT1	S1675	G1677E	1677	Missense	proximal	2	no	7.705	7.848	EPSD	COSMIC	7.780	Gain
AGC_Akt_AKT1_ST	Q3V6T2	CCDC88A	P31749	AKT1	S1675	H1669R	1669	Missense	distal	-6	no	7.705	7.824	EPSD	COSMIC	7.780	Gain
AGC_Akt_AKT1_ST	Q3V6T2	CCDC88A	P31749	AKT1	S1695	K1692R	1692	Missense	distal	-3	no	6.502	11.022	EPSD	COSMIC	7.780	Gain
AGC_Akt_AKT1_ST	Q3V6T2	CCDC88A	P31749	AKT1	S1715	D1708G	1708	Missense	distal	-7	no	7.902	8.088	EPSD	COSMIC	7.780	Up-regulation
AGC_Akt_AKT1_ST	Q3V6T2	CCDC88A	P31749	AKT1	S1715	D1708H	1708	Missense	distal	-7	no	7.902	8.029	EPSD	COSMIC	7.780	Up-regulation
AGC_Akt_AKT1_ST	Q3V6T2	CCDC88A	P31749	AKT1	S1736	P1740S	1740	Missense	distal	4	no	11.281	11.125	EPSD	COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	Q3V6T2	CCDC88A	P31749	AKT1	S1736	V1735L	1735	Missense	proximal	-1	no	11.281	11.287	EPSD	COSMIC	7.780	Up-regulation
AGC_Akt_AKT1_ST	Q3V6T2	CCDC88A	P31749	AKT1	T1764	S1768C	1768	Missense	distal	4	no	8.207	8.552	EPSD	COSMIC	7.780	Up-regulation
AGC_Akt_AKT1_ST	Q3V6T2	CCDC88A	P31749	AKT1	T1764	S1769Y	1769	Missense	distal	5	no	8.207	8.164	EPSD	COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	Q3V6T2	CCDC88A	P31749	AKT1	T1764	K1760N	1760	Missense	distal	-4	no	8.207	7.568	EPSD	COSMIC	7.780	Loss
AGC_Akt_AKT1_ST	Q3V6T2	CCDC88A	P31749	AKT1	T1764	A1770T	1770	Missense	distal	6	no	8.207	8.310	EPSD	COSMIC	7.780	Up-regulation
AGC_Akt_AKT1_ST	Q3V6T2	CCDC88A	P31749	AKT1	T1764	P1758L	1758	Missense	distal	-6	no	8.207	8.221	EPSD	COSMIC	7.780	Up-regulation
AGC_Akt_AKT1_ST	Q3V6T2	CCDC88A	P31749	AKT1	T1764	A1770V	1770	Missense	distal	6	no	8.207	8.176	EPSD	COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	Q3V6T2	CCDC88A	P31749	AKT1	S1796	R1791K	1791	Missense	distal	-5	no	10.067	7.669	EPSD	COSMIC	7.780	Loss
AGC_Akt_AKT1_ST	Q3V6T2	CCDC88A	P31749	AKT1	S1796	P1803S	1803	Missense	distal	7	no	10.067	10.125	EPSD	COSMIC	7.780	Up-regulation
AGC_Akt_AKT1_ST	Q3V6T2	CCDC88A	P31749	AKT1	S1796	S1796C	1796	Missense	central	0	yes	10.067	0.000	EPSD	COSMIC	7.780	Loss
AGC_Akt_AKT1_ST	Q3V6T2	CCDC88A	P31749	AKT1	S1796	A1800E	1800	Missense	distal	4	no	10.067	10.021	EPSD	COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	Q3V6T2	CCDC88A	P31749	AKT1	S1796	P1798L	1798	Missense	proximal	2	no	10.067	9.857	EPSD	COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	Q3V6T2	CCDC88A	P31749	AKT1	S1807	A1812V	1812	Missense	distal	5	no	12.540	12.531	EPSD	COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	Q3V6T2	CCDC88A	P31749	AKT1	S1807	V1808M	1808	Missense	proximal	1	no	12.540	12.478	EPSD	COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	Q3V6T2	CCDC88A	P31749	AKT1	S1807	V1808L	1808	Missense	proximal	1	no	12.540	12.639	EPSD	COSMIC	7.780	Up-regulation
AGC_Akt_AKT1_ST	Q3V6T2	CCDC88A	P31749	AKT1	S1807	P1803S	1803	Missense	distal	-4	no	12.540	13.276	EPSD	COSMIC	7.780	Up-regulation
AGC_Akt_AKT1_ST	Q3V6T2	CCDC88A	P31749	AKT1	S1807	A1800E	1800	Missense	distal	-7	no	12.540	12.539	EPSD	COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	Q3V6T2	CCDC88A	P31749	AKT1	S1807	E1813K	1813	Missense	distal	6	no	12.540	12.609	EPSD	COSMIC	7.780	Up-regulation
AGC_Akt_AKT1_ST	Q3V6T2	CCDC88A	P31749	AKT1	S1807	R1804C	1804	Missense	distal	-3	no	12.540	6.366	EPSD	COSMIC	7.780	Loss
AGC_Akt_AKT1_ST	Q3V6T2	CCDC88A	P31749	AKT1	S1820	R1817K	1817	Missense	distal	-3	no	12.296	7.775	EPSD	COSMIC	7.780	Loss
AGC_Akt_AKT1_ST	Q3V6T2	CCDC88A	P31749	AKT1	S1820	R1817Q	1817	Missense	distal	-3	no	12.296	5.084	EPSD	COSMIC	7.780	Loss
AGC_Akt_AKT1_ST	Q3V6T2	CCDC88A	P31749	AKT1	S1820	F1824S	1824	Missense	distal	4	no	12.296	12.100	EPSD	COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	Q3V6T2	CCDC88A	P31749	AKT1	S1820	E1813K	1813	Missense	distal	-7	no	12.296	12.488	EPSD	COSMIC	7.780	Up-regulation
AGC_Akt_AKT1_ST	Q3V6T2	CCDC88A	P31749	AKT1	S1820	T1815S	1815	Missense	distal	-5	no	12.296	11.555	EPSD	COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	Q3V6T2	CCDC88A	P31749	AKT1	S1820	R1818K	1818	Missense	proximal	-2	no	12.296	12.735	EPSD	COSMIC	7.780	Up-regulation
AGC_Akt_AKT1_ST	Q3V6T2	CCDC88A	P31749	AKT1	S1820	K1827N	1827	Missense	distal	7	no	12.296	12.260	EPSD	COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	Q3V6T2	CCDC88A	P31749	AKT1	S1820	L1825F	1825	Missense	distal	5	no	12.296	12.290	EPSD	COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	P42345	MTOR	P31749	AKT1	T314	G307R	307	Missense	distal	-7	no	11.505	11.747	EPSD	COSMIC	7.780	Up-regulation
AGC_Akt_AKT1_ST	P42345	MTOR	P31749	AKT1	T314	T314N	314	Missense	central	0	yes	11.505	0.000	EPSD	COSMIC	7.780	Loss
AGC_Akt_AKT1_ST	P42345	MTOR	P31749	AKT1	T314	F319L	319	Missense	distal	5	no	11.505	11.511	EPSD	COSMIC	7.780	Up-regulation
AGC_Akt_AKT1_ST	P42345	MTOR	P31749	AKT1	T314	Q320H	320	Missense	distal	6	no	11.505	11.457	EPSD	COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	P42345	MTOR	P31749	AKT1	T631	R628H	628	Missense	distal	-3	no	10.213	5.515	EPSD	COSMIC	7.780	Loss
AGC_Akt_AKT1_ST	P42345	MTOR	P31749	AKT1	T631	S633F	633	Missense	proximal	2	no	10.213	9.636	EPSD	COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	P42345	MTOR	P31749	AKT1	T631	R628C	628	Missense	distal	-3	no	10.213	4.040	EPSD	COSMIC	7.780	Loss
AGC_Akt_AKT1_ST	P42345	MTOR	P31749	AKT1	T631	C626Y	626	Missense	distal	-5	no	10.213	9.682	EPSD	COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	P42345	MTOR	P31749	AKT1	T631	L636P	636	Missense	distal	5	no	10.213	10.227	EPSD	COSMIC	7.780	Up-regulation
AGC_Akt_AKT1_ST	P42345	MTOR	P31749	AKT1	S720	G716S	716	Missense	distal	-4	no	10.171	10.900	EPSD	COSMIC	7.780	Up-regulation
AGC_Akt_AKT1_ST	P42345	MTOR	P31749	AKT1	S720	R717L	717	Missense	distal	-3	no	10.171	3.177	EPSD	COSMIC	7.780	Loss
AGC_Akt_AKT1_ST	P42345	MTOR	P31749	AKT1	S720	V715M	715	Missense	distal	-5	no	10.171	9.963	EPSD	COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	P42345	MTOR	P31749	AKT1	S720	M727V	727	Missense	distal	7	no	10.171	10.175	EPSD	COSMIC	7.780	Up-regulation
AGC_Akt_AKT1_ST	P42345	MTOR	P31749	AKT1	S720	G716D	716	Missense	distal	-4	no	10.171	9.612	EPSD	COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	P42345	MTOR	P31749	AKT1	S720	S720I	720	Missense	central	0	yes	10.171	0.000	EPSD	COSMIC	7.780	Loss
AGC_Akt_AKT1_ST	P42345	MTOR	P31749	AKT1	S913	D911Y	911	Missense	proximal	-2	no	11.968	12.439	EPSD	COSMIC	7.780	Up-regulation
AGC_Akt_AKT1_ST	P42345	MTOR	P31749	AKT1	S913	D907N	907	Missense	distal	-6	no	11.968	12.040	EPSD	COSMIC	7.780	Up-regulation
AGC_Akt_AKT1_ST	P42345	MTOR	P31749	AKT1	S1166	Q1165H	1165	Missense	proximal	-1	no	8.003	7.991	EPSD	COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	P42345	MTOR	P31749	AKT1	S1166	R1161Q	1161	Missense	distal	-5	no	8.003	3.776	EPSD	COSMIC;CCLE	7.780	Loss
AGC_Akt_AKT1_ST	P42345	MTOR	P31749	AKT1	S1166	R1170H	1170	Missense	distal	4	no	8.003	8.188	EPSD	COSMIC	7.780	Up-regulation
AGC_Akt_AKT1_ST	P42345	MTOR	P31749	AKT1	S1166	R1170P	1170	Missense	distal	4	no	8.003	8.148	EPSD	COSMIC	7.780	Up-regulation
AGC_Akt_AKT1_ST	P42345	MTOR	P31749	AKT1	S1288	L1292M	1292	Missense	distal	4	no	10.483	10.458	EPSD	COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	P42345	MTOR	P31749	AKT1	S1288	R1286Q	1286	Missense	proximal	-2	no	10.483	9.970	EPSD	COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	P42345	MTOR	P31749	AKT1	S1288	S1295L	1295	Missense	distal	7	no	10.483	10.416	EPSD	COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	P42345	MTOR	P31749	AKT1	S1821	R1818C	1818	Missense	distal	-3	no	11.710	5.536	EPSD	COSMIC	7.780	Loss
AGC_Akt_AKT1_ST	P42345	MTOR	P31749	AKT1	S1821	H1819Y	1819	Missense	proximal	-2	no	11.710	11.837	EPSD	COSMIC	7.780	Up-regulation
AGC_Akt_AKT1_ST	P42345	MTOR	P31749	AKT1	S1821	H1819D	1819	Missense	proximal	-2	no	11.710	11.366	EPSD	COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	P42345	MTOR	P31749	AKT1	S1893	F1888I	1888	Missense	distal	-5	no	12.435	11.390	EPSD	COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	P42345	MTOR	P31749	AKT1	S1893	L1894F	1894	Missense	proximal	1	no	12.435	12.354	EPSD	COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	P42345	MTOR	P31749	AKT1	S1893	F1889V	1889	Missense	distal	-4	no	12.435	12.509	EPSD	COSMIC	7.780	Up-regulation
AGC_Akt_AKT1_ST	P42345	MTOR	P31749	AKT1	S1893	N1899D	1899	Missense	distal	6	no	12.435	12.354	EPSD	COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	P42345	MTOR	P31749	AKT1	S1893	F1889Y	1889	Missense	distal	-4	no	12.435	12.743	EPSD	COSMIC	7.780	Up-regulation
AGC_Akt_AKT1_ST	P42345	MTOR	P31749	AKT1	T1948	R1950K	1950	Missense	proximal	2	no	10.263	10.451	EPSD	COSMIC	7.780	Up-regulation
AGC_Akt_AKT1_ST	P42345	MTOR	P31749	AKT1	T1948	I1946T	1946	Missense	proximal	-2	no	10.263	11.437	EPSD	COSMIC	7.780	Up-regulation
AGC_Akt_AKT1_ST	P42345	MTOR	P31749	AKT1	T1948	D1947H	1947	Missense	proximal	-1	no	10.263	10.277	EPSD	COSMIC	7.780	Up-regulation
AGC_Akt_AKT1_ST	P42345	MTOR	P31749	AKT1	T1948	R1955C	1955	Missense	distal	7	no	10.263	10.133	EPSD	COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	P42345	MTOR	P31749	AKT1	S2155	I2156T	2156	Missense	proximal	1	no	8.471	8.913	EPSD	COSMIC	7.780	Up-regulation
AGC_Akt_AKT1_ST	P42345	MTOR	P31749	AKT1	S2155	R2152H	2152	Missense	distal	-3	no	8.471	3.772	EPSD	COSMIC	7.780	Loss
AGC_Akt_AKT1_ST	P42345	MTOR	P31749	AKT1	S2155	I2150V	2150	Missense	distal	-5	no	8.471	8.724	EPSD	COSMIC	7.780	Up-regulation
AGC_Akt_AKT1_ST	P42345	MTOR	P31749	AKT1	S2155	Q2154E	2154	Missense	proximal	-1	no	8.471	8.478	EPSD	COSMIC	7.780	Up-regulation
AGC_Akt_AKT1_ST	P42345	MTOR	P31749	AKT1	S2155	P2158L	2158	Missense	distal	3	no	8.471	8.454	EPSD	COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	P42345	MTOR	P31749	AKT1	S2155	P2158S	2158	Missense	distal	3	no	8.471	8.552	EPSD	COSMIC	7.780	Up-regulation
AGC_Akt_AKT1_ST	P42345	MTOR	P31749	AKT1	S2221	L2216I	2216	Missense	distal	-5	no	8.739	8.297	EPSD	COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	P42345	MTOR	P31749	AKT1	S2221	S2215P	2215	Missense	distal	-6	no	8.739	8.674	EPSD	COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	P42345	MTOR	P31749	AKT1	S2221	L2220F	2220	Missense	proximal	-1	no	8.739	8.732	EPSD	COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	P42345	MTOR	P31749	AKT1	S2221	R2224K	2224	Missense	distal	3	no	8.739	8.757	EPSD	COSMIC	7.780	Up-regulation
AGC_Akt_AKT1_ST	P42345	MTOR	P31749	AKT1	T2444	D2447N	2447	Missense	distal	3	no	12.611	12.666	EPSD	COSMIC	7.780	Up-regulation
AGC_Akt_AKT1_ST	P42345	MTOR	P31749	AKT1	T2444	T2446M	2446	Missense	proximal	2	no	12.611	12.269	EPSD	COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	P42345	MTOR	P31749	AKT1	T2446	D2447N	2447	Missense	proximal	1	no	15.598	15.723	PhosphoSitePlus;EPSD	COSMIC	7.780	Up-regulation
AGC_Akt_AKT1_ST	P42345	MTOR	P31749	AKT1	T2446	T2446M	2446	Missense	central	0	yes	15.598	0.000	PhosphoSitePlus;EPSD	COSMIC	7.780	Loss
AGC_Akt_AKT1_ST	P42345	MTOR	P31749	AKT1	S2448	D2447N	2447	Missense	proximal	-1	no	17.580	17.610	EPSD;PhosphoSitePlus	COSMIC	7.780	Up-regulation
AGC_Akt_AKT1_ST	P42345	MTOR	P31749	AKT1	S2448	T2446M	2446	Missense	proximal	-2	no	17.580	16.807	EPSD;PhosphoSitePlus	COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	P42345	MTOR	P31749	AKT1	S2450	D2447N	2447	Missense	distal	-3	no	11.759	10.233	EPSD	COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	P42345	MTOR	P31749	AKT1	S2450	I2457M	2457	Missense	distal	7	no	11.759	11.798	EPSD	COSMIC	7.780	Up-regulation
AGC_Akt_AKT1_ST	P42345	MTOR	P31749	AKT1	S2450	T2446M	2446	Missense	distal	-4	no	11.759	10.794	EPSD	COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	P42345	MTOR	P31749	AKT1	T2473	E2477K	2477	Missense	distal	4	no	8.095	7.994	EPSD	COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	P42345	MTOR	P31749	AKT1	T2473	G2472E	2472	Missense	proximal	-1	no	8.095	8.110	EPSD	COSMIC	7.780	Up-regulation
AGC_Akt_AKT1_ST	P42345	MTOR	P31749	AKT1	T2473	P2476L	2476	Missense	distal	3	no	8.095	8.078	EPSD	COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	P42345	MTOR	P31749	AKT1	T2473	V2475M	2475	Missense	proximal	2	no	8.095	8.216	EPSD	COSMIC	7.780	Up-regulation
AGC_Akt_AKT1_ST	P42345	MTOR	P31749	AKT1	S2514	D2516N	2516	Missense	proximal	2	no	10.472	10.802	EPSD	COSMIC	7.780	Up-regulation
AGC_Akt_AKT1_ST	P42345	MTOR	P31749	AKT1	S2514	D2512H	2512	Missense	proximal	-2	no	10.472	10.816	EPSD	COSMIC	7.780	Up-regulation
AGC_Akt_AKT1_ST	P42345	MTOR	P31749	AKT1	S2514	R2511W	2511	Missense	distal	-3	no	10.472	1.532	EPSD	COSMIC	7.780	Loss
AGC_Akt_AKT1_ST	P42345	MTOR	P31749	AKT1	S2514	D2517G	2517	Missense	distal	3	no	10.472	10.493	EPSD	COSMIC	7.780	Up-regulation
AGC_Akt_AKT1_ST	P42345	MTOR	P31749	AKT1	S2514	K2507R	2507	Missense	distal	-7	no	10.472	10.485	EPSD	COSMIC	7.780	Up-regulation
AGC_Akt_AKT1_ST	P35232	PHB	P31749	AKT1	T108	E112D	112	Missense	distal	4	no	9.561	9.708	EPSD	COSMIC	7.780	Up-regulation
AGC_Akt_AKT1_ST	P35232	PHB	P31749	AKT1	T108	P104L	104	Missense	distal	-4	no	9.561	9.174	EPSD	COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	P35232	PHB	P31749	AKT1	T108	F107L	107	Missense	proximal	-1	no	9.561	9.567	EPSD	COSMIC	7.780	Up-regulation
AGC_Akt_AKT1_ST	P35232	PHB	P31749	AKT1	T108	D115N	115	Missense	distal	7	no	9.561	9.603	EPSD	COSMIC;GDSC;CCLE	7.780	Up-regulation
AGC_Akt_AKT1_ST	P35232	PHB	P31749	AKT1	S151	D153N	153	Missense	proximal	2	no	11.967	12.297	EPSD	COSMIC	7.780	Up-regulation
AGC_Akt_AKT1_ST	P35232	PHB	P31749	AKT1	T258	R253H	253	Missense	distal	-5	no	16.968	13.873	PhosphoSitePlus	COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	P35232	PHB	P31749	AKT1	T258	G263W	263	Missense	distal	5	no	16.968	16.944	PhosphoSitePlus	COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	Q13045	FLII	P31749	AKT1	S90	P97S	97	Missense	distal	7	no	10.721	10.779	EPSD	COSMIC	7.780	Up-regulation
AGC_Akt_AKT1_ST	Q13045	FLII	P31749	AKT1	S90	K92R	92	Missense	proximal	2	no	10.721	10.533	EPSD	COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	Q13045	FLII	P31749	AKT1	S90	V85M	85	Missense	distal	-5	no	10.721	10.513	EPSD	COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	Q13045	FLII	P31749	AKT1	S406	A403P	403	Missense	distal	-3	no	8.560	8.223	EPSD	COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	Q13045	FLII	P31749	AKT1	S406	A403G	403	Missense	distal	-3	no	8.560	8.107	EPSD	COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	Q13045	FLII	P31749	AKT1	S406	A413V	413	Missense	distal	7	no	8.560	8.555	EPSD	COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	Q13045	FLII	P31749	AKT1	S406	A411T	411	Missense	distal	5	no	8.560	8.611	EPSD	COSMIC	7.780	Up-regulation
AGC_Akt_AKT1_ST	Q13045	FLII	P31749	AKT1	S406	A412T	412	Missense	distal	6	no	8.560	8.663	EPSD	COSMIC	7.780	Up-regulation
AGC_Akt_AKT1_ST	Q13045	FLII	P31749	AKT1	S436	R433C	433	Missense	distal	-3	no	16.954	10.781	PhosphoSitePlus	COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	Q13045	FLII	P31749	AKT1	S436	R429L	429	Missense	distal	-7	no	16.954	16.665	PhosphoSitePlus	COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	Q13045	FLII	P31749	AKT1	S436	D440E	440	Missense	distal	4	no	16.954	16.808	PhosphoSitePlus	COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	Q13045	FLII	P31749	AKT1	S436	R432C	432	Missense	distal	-4	no	16.954	15.276	PhosphoSitePlus	COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	Q13045	FLII	P31749	AKT1	S436	D439E	439	Missense	distal	3	no	16.954	17.025	PhosphoSitePlus	COSMIC	7.780	Up-regulation
AGC_Akt_AKT1_ST	Q13045	FLII	P31749	AKT1	T665	K671T	671	Missense	distal	6	no	8.822	8.832	EPSD	COSMIC	7.780	Up-regulation
AGC_Akt_AKT1_ST	Q13045	FLII	P31749	AKT1	T665	R660L	660	Missense	distal	-5	no	8.822	4.696	EPSD	COSMIC	7.780	Loss
AGC_Akt_AKT1_ST	Q13045	FLII	P31749	AKT1	T665	A662G	662	Missense	distal	-3	no	8.822	8.369	EPSD	COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	Q13045	FLII	P31749	AKT1	T665	Q663P	663	Missense	proximal	-2	no	8.822	8.699	EPSD	COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	Q13045	FLII	P31749	AKT1	T665	A672T	672	Missense	distal	7	no	8.822	8.883	EPSD	COSMIC	7.780	Up-regulation
AGC_Akt_AKT1_ST	Q13045	FLII	P31749	AKT1	T818	R813W	813	Missense	distal	-5	no	14.407	8.888	EPSD	COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	Q13045	FLII	P31749	AKT1	T818	R815H	815	Missense	distal	-3	no	14.407	9.709	EPSD	COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	Q13045	FLII	P31749	AKT1	T818	R815C	815	Missense	distal	-3	no	14.407	8.234	EPSD	COSMIC;CCLE	7.780	Down-regulation
AGC_Akt_AKT1_ST	Q9UGI0	ZRANB1	P31749	AKT1	S78	M82I	82	Missense	distal	4	no	15.915	16.013	PhosphoSitePlus;EPSD	COSMIC	7.780	Up-regulation
AGC_Akt_AKT1_ST	Q9UGI0	ZRANB1	P31749	AKT1	S78	R75K	75	Missense	distal	-3	no	15.915	11.395	PhosphoSitePlus;EPSD	COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	Q9UGI0	ZRANB1	P31749	AKT1	T105	R112W	112	Missense	distal	7	no	7.923	7.825	EPSD	COSMIC;GDSC;CCLE	7.780	Down-regulation
AGC_Akt_AKT1_ST	Q9UGI0	ZRANB1	P31749	AKT1	S115	R112W	112	Missense	distal	-3	no	11.781	2.841	EPSD	COSMIC;GDSC;CCLE	7.780	Loss
AGC_Akt_AKT1_ST	Q9UGI0	ZRANB1	P31749	AKT1	S115	S119Y	119	Missense	distal	4	no	11.781	11.917	EPSD	COSMIC	7.780	Up-regulation
AGC_Akt_AKT1_ST	Q9UGI0	ZRANB1	P31749	AKT1	S115	R114M	114	Missense	proximal	-1	no	11.781	11.742	EPSD	COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	Q9UGI0	ZRANB1	P31749	AKT1	T117	R112W	112	Missense	distal	-5	no	17.579	12.059	EPSD;PhosphoSitePlus	COSMIC;GDSC;CCLE	7.780	Down-regulation
AGC_Akt_AKT1_ST	Q9UGI0	ZRANB1	P31749	AKT1	T117	S119Y	119	Missense	proximal	2	no	17.579	17.207	EPSD;PhosphoSitePlus	COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	Q9UGI0	ZRANB1	P31749	AKT1	T117	R114M	114	Missense	distal	-3	no	17.579	10.074	EPSD;PhosphoSitePlus	COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	Q9UGI0	ZRANB1	P31749	AKT1	S119	R112W	112	Missense	distal	-7	no	12.143	11.720	EPSD	COSMIC;GDSC;CCLE	7.780	Down-regulation
AGC_Akt_AKT1_ST	Q9UGI0	ZRANB1	P31749	AKT1	S119	S119Y	119	Missense	central	0	yes	12.143	0.000	EPSD	COSMIC	7.780	Loss
AGC_Akt_AKT1_ST	Q9UGI0	ZRANB1	P31749	AKT1	S119	R114M	114	Missense	distal	-5	no	12.143	7.621	EPSD	COSMIC	7.780	Loss
AGC_Akt_AKT1_ST	Q9UGI0	ZRANB1	P31749	AKT1	S336	T333R	333	Missense	distal	-3	no	2.997	10.018	EPSD	COSMIC	7.780	Gain
AGC_Akt_AKT1_ST	Q9UGI0	ZRANB1	P31749	AKT1	T552	R549Q	549	Missense	distal	-3	no	9.258	2.046	EPSD	COSMIC	7.780	Loss
AGC_Akt_AKT1_ST	Q9UGI0	ZRANB1	P31749	AKT1	T694	P692L	692	Missense	proximal	-2	no	11.373	11.341	EPSD	COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	Q9UGI0	ZRANB1	P31749	AKT1	T694	R691Q	691	Missense	distal	-3	no	11.373	4.162	EPSD	COSMIC	7.780	Loss
AGC_Akt_AKT1_ST	Q13043	STK4	P31749	AKT1	S21	D20N	20	Missense	proximal	-1	no	7.766	7.796	EPSD	COSMIC	7.780	Gain
AGC_Akt_AKT1_ST	Q13043	STK4	P31749	AKT1	T120	R115L	115	Missense	distal	-5	no	13.999	9.873	EPSD;PhosphoSitePlus	COSMIC;GDSC;CCLE	7.780	Down-regulation
AGC_Akt_AKT1_ST	Q13043	STK4	P31749	AKT1	T120	E123K	123	Missense	distal	3	no	13.999	14.043	EPSD;PhosphoSitePlus	COSMIC	7.780	Up-regulation
AGC_Akt_AKT1_ST	Q13043	STK4	P31749	AKT1	T122	R115L	115	Missense	distal	-7	no	11.495	11.205	EPSD	COSMIC;GDSC;CCLE	7.780	Down-regulation
AGC_Akt_AKT1_ST	Q13043	STK4	P31749	AKT1	T122	E123K	123	Missense	proximal	1	no	11.495	11.658	EPSD	COSMIC	7.780	Up-regulation
AGC_Akt_AKT1_ST	Q13043	STK4	P31749	AKT1	S307	R310W	310	Missense	distal	3	no	11.863	11.751	EPSD	COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	Q13043	STK4	P31749	AKT1	S307	V312M	312	Missense	distal	5	no	11.863	11.866	EPSD	COSMIC	7.780	Up-regulation
AGC_Akt_AKT1_ST	Q13043	STK4	P31749	AKT1	S307	R304H	304	Missense	distal	-3	no	11.863	7.164	EPSD	COSMIC	7.780	Loss
AGC_Akt_AKT1_ST	Q13043	STK4	P31749	AKT1	T387	R384S	384	Missense	distal	-3	no	12.521	4.744	EPSD;PhosphoSitePlus	COSMIC	7.780	Loss
AGC_Akt_AKT1_ST	Q99683	MAP3K5	P31749	AKT1	S83	G81S	81	Missense	proximal	-2	no	15.754	16.449	PhosphoSitePlus	COSMIC	7.780	Up-regulation
AGC_Akt_AKT1_ST	Q99683	MAP3K5	P31749	AKT1	S83	G87S	87	Missense	distal	4	no	15.754	15.581	PhosphoSitePlus	COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	Q99683	MAP3K5	P31749	AKT1	S966	V969I	969	Missense	distal	3	no	11.671	11.630	EPSD	COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	Q99683	MAP3K5	P31749	AKT1	T1015	G1012R	1012	Missense	distal	-3	no	3.235	9.991	EPSD	COSMIC	7.780	Gain
AGC_Akt_AKT1_ST	Q99683	MAP3K5	P31749	AKT1	T1059	A1052T	1052	Missense	distal	-7	no	11.135	11.334	EPSD	COSMIC	7.780	Up-regulation
AGC_Akt_AKT1_ST	O43464	HTRA2	P31749	AKT1	S13	G11S	11	Missense	proximal	-2	no	10.311	11.006	EPSD	COSMIC;CCLE	7.780	Up-regulation
AGC_Akt_AKT1_ST	O43464	HTRA2	P31749	AKT1	S41	L39R	39	Missense	proximal	-2	no	9.709	10.377	EPSD	COSMIC	7.780	Up-regulation
AGC_Akt_AKT1_ST	O43464	HTRA2	P31749	AKT1	S44	L39R	39	Missense	distal	-5	no	4.473	8.600	EPSD	COSMIC	7.780	Gain
AGC_Akt_AKT1_ST	O43464	HTRA2	P31749	AKT1	T54	V50G	50	Missense	distal	-4	no	7.629	7.994	EPSD	COSMIC	7.780	Gain
AGC_Akt_AKT1_ST	O43464	HTRA2	P31749	AKT1	S96	T101N	101	Missense	distal	5	no	17.614	17.580	EPSD	COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	O43464	HTRA2	P31749	AKT1	S142	S137R	137	Missense	distal	-5	no	4.107	8.577	EPSD	COSMIC	7.780	Gain
AGC_Akt_AKT1_ST	O43464	HTRA2	P31749	AKT1	S350	R344H	344	Missense	distal	-6	no	9.506	9.387	EPSD	COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	O43464	HTRA2	P31749	AKT1	S350	G356W	356	Missense	distal	6	no	9.506	9.452	EPSD	COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	O43464	HTRA2	P31749	AKT1	S435	R442W	442	Missense	distal	7	no	12.291	12.193	EPSD	COSMIC;GDSC;CCLE	7.780	Down-regulation
AGC_Akt_AKT1_ST	O43464	HTRA2	P31749	AKT1	S435	A430G	430	Missense	distal	-5	no	12.291	12.081	EPSD	COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	O43464	HTRA2	P31749	AKT1	S435	A438T	438	Missense	distal	3	no	12.291	12.348	EPSD	COSMIC	7.780	Up-regulation
AGC_Akt_AKT1_ST	Q9UN36	NDRG2	P31749	AKT1	T330	S328F	328	Missense	proximal	-2	no	10.623	9.756	EPSD	COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	Q9UN36	NDRG2	P31749	AKT1	T330	S332F	332	Missense	proximal	2	no	10.623	10.046	EPSD	COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	Q9UN36	NDRG2	P31749	AKT1	T330	A331S	331	Missense	proximal	1	no	10.623	10.697	EPSD	COSMIC	7.780	Up-regulation
AGC_Akt_AKT1_ST	Q9UN36	NDRG2	P31749	AKT1	T330	L325M	325	Missense	distal	-5	no	10.623	10.227	EPSD	COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	Q9UN36	NDRG2	P31749	AKT1	T330	R324C	324	Missense	distal	-6	no	10.623	10.443	EPSD	COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	Q9UN36	NDRG2	P31749	AKT1	T330	A337E	337	Missense	distal	7	no	10.623	10.640	EPSD	COSMIC	7.780	Up-regulation
AGC_Akt_AKT1_ST	Q9UN36	NDRG2	P31749	AKT1	S332	S328F	328	Missense	distal	-4	no	15.948	14.780	EPSD;PhosphoSitePlus	COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	Q9UN36	NDRG2	P31749	AKT1	S332	S338G	338	Missense	distal	6	no	15.948	15.842	EPSD;PhosphoSitePlus	COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	Q9UN36	NDRG2	P31749	AKT1	S332	S332F	332	Missense	central	0	yes	15.948	0.000	EPSD;PhosphoSitePlus	COSMIC	7.780	Loss
AGC_Akt_AKT1_ST	Q9UN36	NDRG2	P31749	AKT1	S332	A331S	331	Missense	proximal	-1	no	15.948	15.968	EPSD;PhosphoSitePlus	COSMIC	7.780	Up-regulation
AGC_Akt_AKT1_ST	Q9UN36	NDRG2	P31749	AKT1	S332	L325M	325	Missense	distal	-7	no	15.948	15.965	EPSD;PhosphoSitePlus	COSMIC	7.780	Up-regulation
AGC_Akt_AKT1_ST	Q9UN36	NDRG2	P31749	AKT1	S332	A337E	337	Missense	distal	5	no	15.948	15.966	EPSD;PhosphoSitePlus	COSMIC	7.780	Up-regulation
AGC_Akt_AKT1_ST	Q9UN36	NDRG2	P31749	AKT1	T334	S328F	328	Missense	distal	-6	no	9.795	9.721	EPSD	COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	Q9UN36	NDRG2	P31749	AKT1	T334	S338G	338	Missense	distal	4	no	9.795	9.969	EPSD	COSMIC	7.780	Up-regulation
AGC_Akt_AKT1_ST	Q9UN36	NDRG2	P31749	AKT1	T334	S332F	332	Missense	proximal	-2	no	9.795	8.929	EPSD	COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	Q9UN36	NDRG2	P31749	AKT1	T334	A331S	331	Missense	distal	-3	no	9.795	8.322	EPSD	COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	Q9UN36	NDRG2	P31749	AKT1	T334	A337E	337	Missense	distal	3	no	9.795	9.812	EPSD	COSMIC	7.780	Up-regulation
AGC_Akt_AKT1_ST	Q9UN36	NDRG2	P31749	AKT1	S346	L349M	349	Missense	distal	3	no	13.688	13.700	EPSD	COSMIC	7.780	Up-regulation
AGC_Akt_AKT1_ST	Q9UN36	NDRG2	P31749	AKT1	S346	S353G	353	Missense	distal	7	no	13.688	13.614	EPSD	COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	Q9UN36	NDRG2	P31749	AKT1	S346	R345L	345	Missense	proximal	-1	no	13.688	13.649	EPSD	COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	Q9UN36	NDRG2	P31749	AKT1	T348	S355F	355	Missense	distal	7	no	15.892	15.818	PhosphoSitePlus;EPSD	COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	Q9UN36	NDRG2	P31749	AKT1	T348	L349M	349	Missense	proximal	1	no	15.892	15.731	PhosphoSitePlus;EPSD	COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	Q9UN36	NDRG2	P31749	AKT1	T348	S353G	353	Missense	distal	5	no	15.892	15.829	PhosphoSitePlus;EPSD	COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	Q9UN36	NDRG2	P31749	AKT1	T348	R345L	345	Missense	distal	-3	no	15.892	8.898	PhosphoSitePlus;EPSD	COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	Q9UN36	NDRG2	P31749	AKT1	S350	S355F	355	Missense	distal	5	no	19.104	19.032	EPSD	COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	Q9UN36	NDRG2	P31749	AKT1	S350	S353G	353	Missense	distal	3	no	19.104	19.013	EPSD	COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	Q9UN36	NDRG2	P31749	AKT1	S350	R345L	345	Missense	distal	-5	no	19.104	14.978	EPSD	COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	Q9UN36	NDRG2	P31749	AKT1	S352	S359F	359	Missense	distal	7	no	11.781	11.708	EPSD	COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	Q9UN36	NDRG2	P31749	AKT1	S352	S355F	355	Missense	distal	3	no	11.781	11.683	EPSD	COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	Q9UN36	NDRG2	P31749	AKT1	S352	L349M	349	Missense	distal	-3	no	11.781	11.270	EPSD	COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	Q9UN36	NDRG2	P31749	AKT1	S352	S353G	353	Missense	proximal	1	no	11.781	11.477	EPSD	COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	Q9UN36	NDRG2	P31749	AKT1	S352	R345L	345	Missense	distal	-7	no	11.781	11.492	EPSD	COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	Q9UN36	NDRG2	P31749	AKT1	S359	S359F	359	Missense	central	0	yes	7.976	0.000	EPSD	COSMIC	7.780	Loss
AGC_Akt_AKT1_ST	Q9UN36	NDRG2	P31749	AKT1	S359	S355F	355	Missense	distal	-4	no	7.976	6.808	EPSD	COSMIC	7.780	Loss
AGC_Akt_AKT1_ST	Q9UN36	NDRG2	P31749	AKT1	S359	S360L	360	Missense	proximal	1	no	7.976	8.075	EPSD	COSMIC	7.780	Up-regulation
AGC_Akt_AKT1_ST	Q9UN36	NDRG2	P31749	AKT1	S359	P363S	363	Missense	distal	4	no	7.976	7.820	EPSD	COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	Q9UN36	NDRG2	P31749	AKT1	S359	S353G	353	Missense	distal	-6	no	7.976	7.897	EPSD	COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	Q9UN36	NDRG2	P31749	AKT1	S359	P363L	363	Missense	distal	4	no	7.976	8.009	EPSD	COSMIC	7.780	Up-regulation
AGC_Akt_AKT1_ST	Q9UN36	NDRG2	P31749	AKT1	S360	S355F	355	Missense	distal	-5	no	6.878	7.827	EPSD	COSMIC	7.780	Gain
AGC_Akt_AKT1_ST	O95999	BCL10	P31749	AKT1	T52	I46K	46	Missense	distal	-6	no	11.782	11.923	EPSD	COSMIC	7.780	Up-regulation
AGC_Akt_AKT1_ST	O95999	BCL10	P31749	AKT1	T52	E54G	54	Missense	proximal	2	no	11.782	11.639	EPSD	COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	O95999	BCL10	P31749	AKT1	T52	E53Q	53	Missense	proximal	1	no	11.782	11.728	EPSD	COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	O95999	BCL10	P31749	AKT1	S121	G116R	116	Missense	distal	-5	no	4.584	8.649	EPSD	COSMIC	7.780	Gain
AGC_Akt_AKT1_ST	O95999	BCL10	P31749	AKT1	S218	L225F	225	Missense	distal	7	no	9.371	9.364	PhosphoSitePlus;EPSD	COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	O95999	BCL10	P31749	AKT1	S218	G213R	213	Missense	distal	-5	no	9.371	13.436	PhosphoSitePlus;EPSD	COSMIC	7.780	Up-regulation
AGC_Akt_AKT1_ST	O95999	BCL10	P31749	AKT1	S218	P224S	224	Missense	distal	6	no	9.371	9.465	PhosphoSitePlus;EPSD	COSMIC	7.780	Up-regulation
AGC_Akt_AKT1_ST	O95999	BCL10	P31749	AKT1	S227	T229S	229	Missense	proximal	2	no	7.837	7.912	EPSD	COSMIC	7.780	Up-regulation
AGC_Akt_AKT1_ST	O95999	BCL10	P31749	AKT1	S227	L225F	225	Missense	proximal	-2	no	7.837	7.827	EPSD	COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	O95999	BCL10	P31749	AKT1	S227	S227L	227	Missense	central	0	yes	7.837	0.000	EPSD	COSMIC	7.780	Loss
AGC_Akt_AKT1_ST	O95999	BCL10	P31749	AKT1	S227	P224S	224	Missense	distal	-3	no	7.837	6.700	EPSD	COSMIC	7.780	Loss
AGC_Akt_AKT1_ST	O95999	BCL10	P31749	AKT1	T229	L225F	225	Missense	distal	-4	no	12.071	12.027	EPSD	COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	O95999	BCL10	P31749	AKT1	T229	S227L	227	Missense	proximal	-2	no	12.071	11.214	EPSD	COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	O95999	BCL10	P31749	AKT1	T229	P224S	224	Missense	distal	-5	no	12.071	11.611	EPSD	COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	O95999	BCL10	P31749	AKT1	S231	T229S	229	Missense	proximal	-2	no	18.236	18.302	EPSD;PhosphoSitePlus	COSMIC	7.780	Up-regulation
AGC_Akt_AKT1_ST	O95999	BCL10	P31749	AKT1	S231	L225F	225	Missense	distal	-6	no	18.236	18.212	EPSD;PhosphoSitePlus	COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	O95999	BCL10	P31749	AKT1	S231	S227L	227	Missense	distal	-4	no	18.236	17.112	EPSD;PhosphoSitePlus	COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	O95999	BCL10	P31749	AKT1	S231	P224S	224	Missense	distal	-7	no	18.236	18.430	EPSD;PhosphoSitePlus	COSMIC	7.780	Up-regulation
AGC_Akt_AKT1_ST	P35240	NF2	P31749	AKT1	S13	S13Y	13	Missense	central	0	yes	9.220	0.000	EPSD	COSMIC	7.780	Loss
AGC_Akt_AKT1_ST	P35240	NF2	P31749	AKT1	S13	M9T	9	Missense	distal	-4	no	9.220	10.186	EPSD	COSMIC	7.780	Up-regulation
AGC_Akt_AKT1_ST	P35240	NF2	P31749	AKT1	S13	R8L	8	Missense	distal	-5	no	9.220	5.094	EPSD	COSMIC	7.780	Loss
AGC_Akt_AKT1_ST	P35240	NF2	P31749	AKT1	S13	P19R	19	Missense	distal	6	no	9.220	9.312	EPSD	COSMIC	7.780	Up-regulation
AGC_Akt_AKT1_ST	P35240	NF2	P31749	AKT1	T230	R225Q	225	Missense	distal	-5	no	10.354	6.126	EPSD;PhosphoSitePlus	COSMIC	7.780	Loss
AGC_Akt_AKT1_ST	P35240	NF2	P31749	AKT1	T230	G235R	235	Missense	distal	5	no	10.354	10.424	EPSD;PhosphoSitePlus	COSMIC	7.780	Up-regulation
AGC_Akt_AKT1_ST	P35240	NF2	P31749	AKT1	T230	G235E	235	Missense	distal	5	no	10.354	10.384	EPSD;PhosphoSitePlus	COSMIC	7.780	Up-regulation
AGC_Akt_AKT1_ST	P35240	NF2	P31749	AKT1	S265	R262Q	262	Missense	distal	-3	no	9.943	2.732	EPSD	COSMIC	7.780	Loss
AGC_Akt_AKT1_ST	P35240	NF2	P31749	AKT1	S265	E270D	270	Missense	distal	5	no	9.943	9.901	EPSD	COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	P35240	NF2	P31749	AKT1	S267	R262Q	262	Missense	distal	-5	no	8.370	4.143	EPSD	COSMIC	7.780	Loss
AGC_Akt_AKT1_ST	P35240	NF2	P31749	AKT1	S267	E270D	270	Missense	distal	3	no	8.370	8.300	EPSD	COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	P35240	NF2	P31749	AKT1	S267	I273F	273	Missense	distal	6	no	8.370	8.415	EPSD	COSMIC	7.780	Up-regulation
AGC_Akt_AKT1_ST	P35240	NF2	P31749	AKT1	S315	S315Y	315	Missense	central	0	yes	11.067	0.000	PhosphoSitePlus;EPSD	COSMIC	7.780	Loss
AGC_Akt_AKT1_ST	P35240	NF2	P31749	AKT1	S315	D314N	314	Missense	proximal	-1	no	11.067	11.097	PhosphoSitePlus;EPSD	COSMIC	7.780	Up-regulation
AGC_Akt_AKT1_ST	P35240	NF2	P31749	AKT1	S315	Q319H	319	Missense	distal	4	no	11.067	11.129	PhosphoSitePlus;EPSD	COSMIC	7.780	Up-regulation
AGC_Akt_AKT1_ST	P35240	NF2	P31749	AKT1	S315	Q320R	320	Missense	distal	5	no	11.067	11.118	PhosphoSitePlus;EPSD	COSMIC	7.780	Up-regulation
AGC_Akt_AKT1_ST	P35240	NF2	P31749	AKT1	S315	K322I	322	Missense	distal	7	no	11.067	10.970	PhosphoSitePlus;EPSD	COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	P35240	NF2	P31749	AKT1	S315	R309C	309	Missense	distal	-6	no	11.067	10.887	PhosphoSitePlus;EPSD	COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	P35240	NF2	P31749	AKT1	S315	R309H	309	Missense	distal	-6	no	11.067	10.948	PhosphoSitePlus;EPSD	COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	P35240	NF2	P31749	AKT1	S315	R310C	310	Missense	distal	-5	no	11.067	6.990	PhosphoSitePlus;EPSD	COSMIC	7.780	Loss
AGC_Akt_AKT1_ST	P35240	NF2	P31749	AKT1	S315	R310H	310	Missense	distal	-5	no	11.067	7.972	PhosphoSitePlus;EPSD	COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	P35240	NF2	P31749	AKT1	S571	E564K	564	Missense	distal	-7	no	11.247	11.439	EPSD	COSMIC	7.780	Up-regulation
AGC_Akt_AKT1_ST	P35240	NF2	P31749	AKT1	S571	G569S	569	Missense	proximal	-2	no	11.247	11.941	EPSD	COSMIC	7.780	Up-regulation
AGC_Akt_AKT1_ST	P35240	NF2	P31749	AKT1	T581	K579N	579	Missense	proximal	-2	no	8.855	7.919	EPSD	COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	P35240	NF2	P31749	AKT1	T581	R588Q	588	Missense	distal	7	no	8.855	8.799	EPSD	COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	P35240	NF2	P31749	AKT1	T581	R588L	588	Missense	distal	7	no	8.855	8.781	EPSD	COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	P35240	NF2	P31749	AKT1	T581	L580F	580	Missense	proximal	-1	no	8.855	8.849	EPSD	COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	P35240	NF2	P31749	AKT1	T581	K586N	586	Missense	distal	5	no	8.855	8.819	EPSD	COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	P35240	NF2	P31749	AKT1	S584	K579N	579	Missense	distal	-5	no	8.521	6.434	EPSD	COSMIC	7.780	Loss
AGC_Akt_AKT1_ST	P35240	NF2	P31749	AKT1	S584	V589M	589	Missense	distal	5	no	8.521	8.524	EPSD	COSMIC	7.780	Up-regulation
AGC_Akt_AKT1_ST	P35240	NF2	P31749	AKT1	S584	A590D	590	Missense	distal	6	no	8.521	8.454	EPSD	COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	P35240	NF2	P31749	AKT1	S584	R588Q	588	Missense	distal	4	no	8.521	8.645	EPSD	COSMIC	7.780	Up-regulation
AGC_Akt_AKT1_ST	P35240	NF2	P31749	AKT1	S584	R588L	588	Missense	distal	4	no	8.521	8.699	EPSD	COSMIC	7.780	Up-regulation
AGC_Akt_AKT1_ST	P35240	NF2	P31749	AKT1	S584	A590T	590	Missense	distal	6	no	8.521	8.624	EPSD	COSMIC	7.780	Up-regulation
AGC_Akt_AKT1_ST	P35240	NF2	P31749	AKT1	S584	L580F	580	Missense	distal	-4	no	8.521	8.478	EPSD	COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	P35240	NF2	P31749	AKT1	S584	K586N	586	Missense	proximal	2	no	8.521	8.236	EPSD	COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	Q92547	TOPBP1	P31749	AKT1	T185	T188A	188	Missense	distal	3	no	7.886	7.829	EPSD	COSMIC;GDSC;CCLE	7.780	Down-regulation
AGC_Akt_AKT1_ST	Q92547	TOPBP1	P31749	AKT1	S471	N469S	469	Missense	proximal	-2	no	9.143	9.829	EPSD	COSMIC;GDSC;CCLE	7.780	Up-regulation
AGC_Akt_AKT1_ST	Q92547	TOPBP1	P31749	AKT1	T779	P780L	780	Missense	proximal	1	no	8.056	8.310	EPSD	COSMIC	7.780	Up-regulation
AGC_Akt_AKT1_ST	Q92547	TOPBP1	P31749	AKT1	T779	T776P	776	Missense	distal	-3	no	8.056	8.438	EPSD	COSMIC	7.780	Up-regulation
AGC_Akt_AKT1_ST	Q92547	TOPBP1	P31749	AKT1	T779	T776I	776	Missense	distal	-3	no	8.056	7.997	EPSD	COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	Q92547	TOPBP1	P31749	AKT1	T779	F786C	786	Missense	distal	7	no	8.056	8.008	EPSD	COSMIC;GDSC;CCLE	7.780	Down-regulation
AGC_Akt_AKT1_ST	Q92547	TOPBP1	P31749	AKT1	S788	R792C	792	Missense	distal	4	no	10.424	10.758	EPSD	COSMIC;CCLE	7.780	Up-regulation
AGC_Akt_AKT1_ST	Q92547	TOPBP1	P31749	AKT1	S788	A790G	790	Missense	proximal	2	no	10.424	10.468	EPSD	COSMIC	7.780	Up-regulation
AGC_Akt_AKT1_ST	Q92547	TOPBP1	P31749	AKT1	S788	F786C	786	Missense	proximal	-2	no	10.424	9.638	EPSD	COSMIC;GDSC;CCLE	7.780	Down-regulation
AGC_Akt_AKT1_ST	Q92547	TOPBP1	P31749	AKT1	S805	R800T	800	Missense	distal	-5	no	9.379	5.649	EPSD	COSMIC	7.780	Loss
AGC_Akt_AKT1_ST	Q92547	TOPBP1	P31749	AKT1	S860	R857M	857	Missense	distal	-3	no	12.893	5.387	EPSD	COSMIC	7.780	Loss
AGC_Akt_AKT1_ST	Q92547	TOPBP1	P31749	AKT1	S860	V866G	866	Missense	distal	6	no	12.893	12.901	EPSD	COSMIC	7.780	Up-regulation
AGC_Akt_AKT1_ST	Q92547	TOPBP1	P31749	AKT1	S860	S853N	853	Missense	distal	-7	no	12.893	12.779	EPSD	COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	Q92547	TOPBP1	P31749	AKT1	S921	A927V	927	Missense	distal	6	no	8.988	8.956	EPSD	COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	Q92547	TOPBP1	P31749	AKT1	S1159	C1166Y	1166	Missense	distal	7	no	15.377	15.457	PhosphoSitePlus	COSMIC	7.780	Up-regulation
AGC_Akt_AKT1_ST	Q92547	TOPBP1	P31749	AKT1	S1216	P1222S	1222	Missense	distal	6	no	8.218	8.312	EPSD	COSMIC	7.780	Up-regulation
AGC_Akt_AKT1_ST	Q92547	TOPBP1	P31749	AKT1	S1216	P1211L	1211	Missense	distal	-5	no	8.218	8.102	EPSD	COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	Q92547	TOPBP1	P31749	AKT1	S1216	K1212T	1212	Missense	distal	-4	no	8.218	8.202	EPSD	COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	Q92547	TOPBP1	P31749	AKT1	T1256	P1250H	1250	Missense	distal	-6	no	10.715	10.694	EPSD	COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	Q15672	TWIST1	P31749	AKT1	T121	R120C	120	Missense	proximal	-1	no	14.091	14.021	PhosphoSitePlus;EPSD	COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	Q15672	TWIST1	P31749	AKT1	S123	R120C	120	Missense	distal	-3	no	16.369	10.196	EPSD;PhosphoSitePlus	COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	P00533	EGFR	P31749	AKT1	S227	G221V	221	Missense	distal	-6	no	14.385	14.389	EPSD	COSMIC	7.780	Up-regulation
AGC_Akt_AKT1_ST	P00533	EGFR	P31749	AKT1	S227	R222H	222	Missense	distal	-5	no	14.385	11.290	EPSD	COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	P00533	EGFR	P31749	AKT1	S227	G221W	221	Missense	distal	-6	no	14.385	14.351	EPSD	COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	P00533	EGFR	P31749	AKT1	S227	S227Y	227	Missense	central	0	yes	14.385	0.000	EPSD	COSMIC	7.780	Loss
AGC_Akt_AKT1_ST	P00533	EGFR	P31749	AKT1	S227	G225C	225	Missense	proximal	-2	no	14.385	13.427	EPSD	COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	P00533	EGFR	P31749	AKT1	S227	S220F	220	Missense	distal	-7	no	14.385	14.107	EPSD	COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	P00533	EGFR	P31749	AKT1	S227	C231S	231	Missense	distal	4	no	14.385	14.040	EPSD	COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	P00533	EGFR	P31749	AKT1	S229	R222H	222	Missense	distal	-7	no	10.795	10.493	PhosphoSitePlus	COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	P00533	EGFR	P31749	AKT1	S229	S227Y	227	Missense	proximal	-2	no	10.795	9.873	PhosphoSitePlus	COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	P00533	EGFR	P31749	AKT1	S229	G225C	225	Missense	distal	-4	no	10.795	9.931	PhosphoSitePlus	COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	P00533	EGFR	P31749	AKT1	S229	C231S	231	Missense	proximal	2	no	10.795	11.619	PhosphoSitePlus	COSMIC	7.780	Up-regulation
AGC_Akt_AKT1_ST	P00533	EGFR	P31749	AKT1	S645	T648A	648	Missense	distal	3	no	7.881	7.824	EPSD	COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	P00533	EGFR	P31749	AKT1	S645	P641H	641	Missense	distal	-4	no	7.881	7.644	EPSD	COSMIC	7.780	Loss
AGC_Akt_AKT1_ST	P00533	EGFR	P31749	AKT1	S645	K642N	642	Missense	distal	-3	no	7.881	4.925	EPSD	COSMIC	7.780	Loss
AGC_Akt_AKT1_ST	P00533	EGFR	P31749	AKT1	S645	P644S	644	Missense	proximal	-1	no	7.881	7.910	EPSD	COSMIC	7.780	Up-regulation
AGC_Akt_AKT1_ST	P00533	EGFR	P31749	AKT1	S645	A647T	647	Missense	proximal	2	no	7.881	8.182	EPSD	COSMIC	7.780	Up-regulation
AGC_Akt_AKT1_ST	P00533	EGFR	P31749	AKT1	S645	I643V	643	Missense	proximal	-2	no	7.881	7.932	EPSD	COSMIC	7.780	Up-regulation
AGC_Akt_AKT1_ST	P00533	EGFR	P31749	AKT1	S645	G652R	652	Missense	distal	7	no	7.881	7.962	EPSD	COSMIC	7.780	Up-regulation
AGC_Akt_AKT1_ST	P00533	EGFR	P31749	AKT1	S645	G652W	652	Missense	distal	7	no	7.881	7.863	EPSD	COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	P00533	EGFR	P31749	AKT1	T678	R680Q	680	Missense	proximal	2	no	12.009	11.892	EPSD	COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	P00533	EGFR	P31749	AKT1	T678	V674F	674	Missense	distal	-4	no	12.009	11.935	EPSD	COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	P00533	EGFR	P31749	AKT1	T678	R675Q	675	Missense	distal	-3	no	12.009	4.798	EPSD	COSMIC;GDSC	7.780	Loss
AGC_Akt_AKT1_ST	P00533	EGFR	P31749	AKT1	T678	R680W	680	Missense	proximal	2	no	12.009	11.554	EPSD	COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	P00533	EGFR	P31749	AKT1	T678	H672Y	672	Missense	distal	-6	no	12.009	12.035	EPSD	COSMIC	7.780	Up-regulation
AGC_Akt_AKT1_ST	P00533	EGFR	P31749	AKT1	T678	R680G	680	Missense	proximal	2	no	12.009	11.849	EPSD	COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	P00533	EGFR	P31749	AKT1	T678	K676R	676	Missense	proximal	-2	no	12.009	11.570	EPSD	COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	P00533	EGFR	P31749	AKT1	T678	R671C	671	Missense	distal	-7	no	12.009	11.530	EPSD	COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	P00533	EGFR	P31749	AKT1	T678	R677C	677	Missense	proximal	-1	no	12.009	11.939	EPSD	COSMIC;GDSC;CCLE	7.780	Down-regulation
AGC_Akt_AKT1_ST	P00533	EGFR	P31749	AKT1	T678	R671H	671	Missense	distal	-7	no	12.009	11.708	EPSD	COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	P00533	EGFR	P31749	AKT1	S752	E749K	749	Missense	distal	-3	no	6.636	8.688	EPSD	COSMIC	7.780	Gain
AGC_Akt_AKT1_ST	P00533	EGFR	P31749	AKT1	T892	Y891D	891	Missense	proximal	-1	no	9.917	9.894	EPSD	COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	P00533	EGFR	P31749	AKT1	T892	L887I	887	Missense	distal	-5	no	9.917	9.475	EPSD	COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	P00533	EGFR	P31749	AKT1	T892	H893R	893	Missense	proximal	1	no	9.917	10.239	EPSD	COSMIC	7.780	Up-regulation
AGC_Akt_AKT1_ST	P00533	EGFR	P31749	AKT1	T892	V897I	897	Missense	distal	5	no	9.917	9.879	EPSD	COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	P00533	EGFR	P31749	AKT1	T892	V897A	897	Missense	distal	5	no	9.917	9.925	EPSD	COSMIC	7.780	Up-regulation
AGC_Akt_AKT1_ST	P00533	EGFR	P31749	AKT1	T892	R889G	889	Missense	distal	-3	no	9.917	3.160	EPSD	COSMIC	7.780	Loss
AGC_Akt_AKT1_ST	P00533	EGFR	P31749	AKT1	S991	F997L	997	Missense	distal	6	no	10.653	10.669	EPSD	COSMIC	7.780	Up-regulation
AGC_Akt_AKT1_ST	P00533	EGFR	P31749	AKT1	S991	D984N	984	Missense	distal	-7	no	10.653	10.910	EPSD	COSMIC	7.780	Up-regulation
AGC_Akt_AKT1_ST	P00533	EGFR	P31749	AKT1	S991	M987R	987	Missense	distal	-4	no	10.653	11.648	EPSD	COSMIC	7.780	Up-regulation
AGC_Akt_AKT1_ST	P00533	EGFR	P31749	AKT1	S1036	T1041A	1041	Missense	distal	5	no	10.626	10.575	EPSD	COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	P00533	EGFR	P31749	AKT1	S1036	S1036R	1036	Missense	central	0	yes	10.626	0.000	EPSD	COSMIC	7.780	Loss
AGC_Akt_AKT1_ST	P00533	EGFR	P31749	AKT1	S1036	L1034I	1034	Missense	proximal	-2	no	10.626	10.242	EPSD	COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	P00533	EGFR	P31749	AKT1	S1039	S1036R	1036	Missense	distal	-3	no	4.046	11.823	EPSD	COSMIC	7.780	Gain
AGC_Akt_AKT1_ST	P00533	EGFR	P31749	AKT1	S1071	F1065L	1065	Missense	distal	-6	no	10.987	11.011	EPSD	COSMIC	7.780	Up-regulation
AGC_Akt_AKT1_ST	P00533	EGFR	P31749	AKT1	S1071	G1075D	1075	Missense	distal	4	no	10.987	11.038	EPSD	COSMIC	7.780	Up-regulation
AGC_Akt_AKT1_ST	P00533	EGFR	P31749	AKT1	S1071	Q1067L	1067	Missense	distal	-4	no	10.987	10.399	EPSD	COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	P00533	EGFR	P31749	AKT1	S1071	Y1069C	1069	Missense	proximal	-2	no	10.987	10.256	EPSD	COSMIC;GDSC;CCLE	7.780	Down-regulation
AGC_Akt_AKT1_ST	P00533	EGFR	P31749	AKT1	S1071	S1064G	1064	Missense	distal	-7	no	10.987	10.801	EPSD	COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	P00533	EGFR	P31749	AKT1	S1071	S1071L	1071	Missense	central	0	yes	10.987	0.000	EPSD	COSMIC	7.780	Loss
AGC_Akt_AKT1_ST	P00533	EGFR	P31749	AKT1	S1071	S1064R	1064	Missense	distal	-7	no	10.987	11.043	EPSD	COSMIC	7.780	Up-regulation
AGC_Akt_AKT1_ST	P00533	EGFR	P31749	AKT1	S1071	S1070T	1070	Missense	proximal	-1	no	10.987	10.993	EPSD	COSMIC	7.780	Up-regulation
AGC_Akt_AKT1_ST	P00533	EGFR	P31749	AKT1	S1071	S1064N	1064	Missense	distal	-7	no	10.987	10.873	EPSD	COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	P00533	EGFR	P31749	AKT1	S1190	G1189D	1189	Missense	proximal	-1	no	7.988	7.969	EPSD	COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	P00533	EGFR	P31749	AKT1	S1190	K1188T	1188	Missense	proximal	-2	no	7.988	7.671	EPSD	COSMIC	7.780	Loss
AGC_Akt_AKT1_ST	P00533	EGFR	P31749	AKT1	S1190	K1188E	1188	Missense	proximal	-2	no	7.988	7.329	EPSD	COSMIC	7.780	Loss
AGC_Akt_AKT1_ST	P00533	EGFR	P31749	AKT1	S1190	N1184D	1184	Missense	distal	-6	no	7.988	7.916	EPSD	COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	P00533	EGFR	P31749	AKT1	S1190	G1185S	1185	Missense	distal	-5	no	7.988	7.582	EPSD	COSMIC	7.780	Loss
AGC_Akt_AKT1_ST	P00533	EGFR	P31749	AKT1	S1204	R1199M	1199	Missense	distal	-5	no	11.475	6.953	EPSD	COSMIC	7.780	Loss
AGC_Akt_AKT1_ST	P00533	EGFR	P31749	AKT1	S1204	S1204R	1204	Missense	central	0	yes	11.475	0.000	EPSD	COSMIC	7.780	Loss
AGC_Akt_AKT1_ST	P00533	EGFR	P31749	AKT1	S1204	A1201T	1201	Missense	distal	-3	no	11.475	10.756	EPSD	COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	P00533	EGFR	P31749	AKT1	S1204	F1207C	1207	Missense	distal	3	no	11.475	11.396	EPSD	COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	P00533	EGFR	P31749	AKT1	S1204	R1199T	1199	Missense	distal	-5	no	11.475	7.745	EPSD	COSMIC	7.780	Loss
AGC_Akt_AKT1_ST	P00533	EGFR	P31749	AKT1	S1204	V1200I	1200	Missense	distal	-4	no	11.475	11.187	EPSD	COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	Q8TDN4	CABLES1	P31749	AKT1	S67	L74V	74	Missense	distal	7	no	10.220	10.231	EPSD	COSMIC	7.780	Up-regulation
AGC_Akt_AKT1_ST	Q8TDN4	CABLES1	P31749	AKT1	S242	G246R	246	Missense	distal	4	no	14.471	14.309	EPSD	COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	Q8TDN4	CABLES1	P31749	AKT1	S287	R284C	284	Missense	distal	-3	no	16.255	10.082	EPSD	COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	Q8TDN4	CABLES1	P31749	AKT1	S287	R284H	284	Missense	distal	-3	no	16.255	11.557	EPSD	COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	Q8TDN4	CABLES1	P31749	AKT1	T309	R308Q	308	Missense	proximal	-1	no	10.541	10.509	EPSD;PhosphoSitePlus	COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	Q8TDN4	CABLES1	P31749	AKT1	T309	P314S	314	Missense	distal	5	no	10.541	10.594	EPSD;PhosphoSitePlus	COSMIC	7.780	Up-regulation
AGC_Akt_AKT1_ST	Q8TDN4	CABLES1	P31749	AKT1	T309	R305Q	305	Missense	distal	-4	no	10.541	9.920	EPSD;PhosphoSitePlus	COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	Q8TDN4	CABLES1	P31749	AKT1	T309	P303T	303	Missense	distal	-6	no	10.541	10.636	EPSD;PhosphoSitePlus	COSMIC	7.780	Up-regulation
AGC_Akt_AKT1_ST	Q8TDN4	CABLES1	P31749	AKT1	S311	R308Q	308	Missense	distal	-3	no	15.323	8.112	EPSD	COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	Q8TDN4	CABLES1	P31749	AKT1	S311	P314S	314	Missense	distal	3	no	15.323	15.405	EPSD	COSMIC	7.780	Up-regulation
AGC_Akt_AKT1_ST	Q8TDN4	CABLES1	P31749	AKT1	S311	K317R	317	Missense	distal	6	no	15.323	15.312	EPSD	COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	Q8TDN4	CABLES1	P31749	AKT1	S311	R305Q	305	Missense	distal	-6	no	15.323	15.239	EPSD	COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	Q8TDN4	CABLES1	P31749	AKT1	S313	R308Q	308	Missense	distal	-5	no	10.129	5.901	EPSD	COSMIC	7.780	Loss
AGC_Akt_AKT1_ST	Q8TDN4	CABLES1	P31749	AKT1	S313	P314S	314	Missense	proximal	1	no	10.129	10.284	EPSD	COSMIC	7.780	Up-regulation
AGC_Akt_AKT1_ST	Q8TDN4	CABLES1	P31749	AKT1	S313	K317R	317	Missense	distal	4	no	10.129	10.162	EPSD	COSMIC	7.780	Up-regulation
AGC_Akt_AKT1_ST	Q8TDN4	CABLES1	P31749	AKT1	S429	S432C	432	Missense	distal	3	no	11.263	11.085	EPSD	COSMIC;GDSC;CCLE	7.780	Down-regulation
AGC_Akt_AKT1_ST	Q8TDN4	CABLES1	P31749	AKT1	S429	L433F	433	Missense	distal	4	no	11.263	11.270	EPSD	COSMIC	7.780	Up-regulation
AGC_Akt_AKT1_ST	Q8TDN4	CABLES1	P31749	AKT1	S429	R431H	431	Missense	proximal	2	no	11.263	10.901	EPSD	COSMIC;GDSC;CCLE	7.780	Down-regulation
AGC_Akt_AKT1_ST	Q8TDN4	CABLES1	P31749	AKT1	S434	G440S	440	Missense	distal	6	no	12.832	12.937	EPSD	COSMIC	7.780	Up-regulation
AGC_Akt_AKT1_ST	Q8TDN4	CABLES1	P31749	AKT1	S434	S432C	432	Missense	proximal	-2	no	12.832	11.179	EPSD	COSMIC;GDSC;CCLE	7.780	Down-regulation
AGC_Akt_AKT1_ST	Q8TDN4	CABLES1	P31749	AKT1	S434	R437Q	437	Missense	distal	3	no	12.832	12.776	EPSD	COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	Q8TDN4	CABLES1	P31749	AKT1	S434	L433F	433	Missense	proximal	-1	no	12.832	12.826	EPSD	COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	Q8TDN4	CABLES1	P31749	AKT1	S434	R431H	431	Missense	distal	-3	no	12.832	8.133	EPSD	COSMIC;GDSC;CCLE	7.780	Down-regulation
AGC_Akt_AKT1_ST	P38936	CDKN1A	P31749	AKT1	T97	G90R	90	Missense	distal	-7	no	11.891	12.134	EPSD	COSMIC	7.780	Up-regulation
AGC_Akt_AKT1_ST	P38936	CDKN1A	P31749	AKT1	T97	T97I	97	Missense	central	0	yes	11.891	0.000	EPSD	COSMIC	7.780	Loss
AGC_Akt_AKT1_ST	P38936	CDKN1A	P31749	AKT1	S98	T97I	97	Missense	proximal	-1	no	8.115	8.060	EPSD	COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	P38936	CDKN1A	P31749	AKT1	T145	D149N	149	Missense	distal	4	no	17.056	16.941	EPSD;PhosphoSitePlus	COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	P38936	CDKN1A	P31749	AKT1	T145	R143W	143	Missense	proximal	-2	no	17.056	15.802	EPSD;PhosphoSitePlus	COSMIC;GDSC;CCLE	7.780	Down-regulation
AGC_Akt_AKT1_ST	P38936	CDKN1A	P31749	AKT1	T145	Q138E	138	Missense	distal	-7	no	17.056	17.044	EPSD;PhosphoSitePlus	COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	P38936	CDKN1A	P31749	AKT1	T145	G139C	139	Missense	distal	-6	no	17.056	16.989	EPSD;PhosphoSitePlus	COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	P38936	CDKN1A	P31749	AKT1	S146	T145S	145	Missense	proximal	-1	no	16.217	16.211	PhosphoSitePlus;EPSD	COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	P38936	CDKN1A	P31749	AKT1	S146	D149N	149	Missense	distal	3	no	16.217	16.272	PhosphoSitePlus;EPSD	COSMIC	7.780	Up-regulation
AGC_Akt_AKT1_ST	P38936	CDKN1A	P31749	AKT1	S146	R143W	143	Missense	distal	-3	no	16.217	7.276	PhosphoSitePlus;EPSD	COSMIC;GDSC;CCLE	7.780	Loss
AGC_Akt_AKT1_ST	P38936	CDKN1A	P31749	AKT1	S146	G139C	139	Missense	distal	-7	no	16.217	15.980	PhosphoSitePlus;EPSD	COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	P38936	CDKN1A	P31749	AKT1	S153	R156W	156	Missense	distal	3	no	9.724	9.612	EPSD	COSMIC;GDSC;CCLE	7.780	Down-regulation
AGC_Akt_AKT1_ST	P38936	CDKN1A	P31749	AKT1	S153	I158M	158	Missense	distal	5	no	9.724	9.764	EPSD	COSMIC	7.780	Up-regulation
AGC_Akt_AKT1_ST	P38936	CDKN1A	P31749	AKT1	S153	D149N	149	Missense	distal	-4	no	9.724	10.445	EPSD	COSMIC	7.780	Up-regulation
AGC_Akt_AKT1_ST	P38936	CDKN1A	P31749	AKT1	S153	R155C	155	Missense	proximal	2	no	9.724	9.071	EPSD	COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	P38936	CDKN1A	P31749	AKT1	S160	R156W	156	Missense	distal	-4	no	10.380	8.831	EPSD	COSMIC;GDSC;CCLE	7.780	Down-regulation
AGC_Akt_AKT1_ST	P38936	CDKN1A	P31749	AKT1	S160	I158M	158	Missense	proximal	-2	no	10.380	10.781	EPSD	COSMIC	7.780	Up-regulation
AGC_Akt_AKT1_ST	P38936	CDKN1A	P31749	AKT1	S160	R155C	155	Missense	distal	-5	no	10.380	6.303	EPSD	COSMIC	7.780	Loss
AGC_Akt_AKT1_ST	O75030	MITF	P31749	AKT1	S405	L406H	406	Missense	proximal	1	no	10.170	9.894	EPSD	COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	O75030	MITF	P31749	AKT1	S405	A399D	399	Missense	distal	-6	no	10.170	10.107	EPSD	COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	O75030	MITF	P31749	AKT1	S405	S405I	405	Missense	central	0	yes	10.170	0.000	EPSD	COSMIC	7.780	Loss
AGC_Akt_AKT1_ST	O75030	MITF	P31749	AKT1	S405	R400W	400	Missense	distal	-5	no	10.170	4.650	EPSD	COSMIC	7.780	Loss
AGC_Akt_AKT1_ST	O75030	MITF	P31749	AKT1	S511	A507T	507	Missense	distal	-4	no	7.238	8.016	EPSD	COSMIC	7.780	Gain
AGC_Akt_AKT1_ST	O75030	MITF	P31749	AKT1	S512	S512I	512	Missense	central	0	yes	11.955	0.000	EPSD	COSMIC	7.780	Loss
AGC_Akt_AKT1_ST	O75030	MITF	P31749	AKT1	S512	A507T	507	Missense	distal	-5	no	11.955	12.079	EPSD	COSMIC	7.780	Up-regulation
AGC_Akt_AKT1_ST	O75030	MITF	P31749	AKT1	S512	R513W	513	Missense	proximal	1	no	11.955	11.662	EPSD	COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	O75030	MITF	P31749	AKT1	S512	S518I	518	Missense	distal	6	no	11.955	11.790	EPSD	COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	O75030	MITF	P31749	AKT1	S512	S511I	511	Missense	proximal	-1	no	11.955	11.905	EPSD	COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	O75030	MITF	P31749	AKT1	S515	S512I	512	Missense	distal	-3	no	8.872	9.568	EPSD	COSMIC	7.780	Up-regulation
AGC_Akt_AKT1_ST	O75030	MITF	P31749	AKT1	S515	R513W	513	Missense	proximal	-2	no	8.872	7.618	EPSD	COSMIC	7.780	Loss
AGC_Akt_AKT1_ST	O75030	MITF	P31749	AKT1	S515	T522M	522	Missense	distal	7	no	8.872	8.803	EPSD	COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	O75030	MITF	P31749	AKT1	S515	S518I	518	Missense	distal	3	no	8.872	8.741	EPSD	COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	O75030	MITF	P31749	AKT1	S515	S511I	511	Missense	distal	-4	no	8.872	7.491	EPSD	COSMIC	7.780	Loss
AGC_Akt_AKT1_ST	O75030	MITF	P31749	AKT1	S516	S512I	512	Missense	distal	-4	no	15.700	14.319	PhosphoSitePlus	COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	O75030	MITF	P31749	AKT1	S516	R513W	513	Missense	distal	-3	no	15.700	6.760	PhosphoSitePlus	COSMIC	7.780	Loss
AGC_Akt_AKT1_ST	O75030	MITF	P31749	AKT1	S516	T522M	522	Missense	distal	6	no	15.700	15.581	PhosphoSitePlus	COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	O75030	MITF	P31749	AKT1	S516	S518I	518	Missense	proximal	2	no	15.700	15.044	PhosphoSitePlus	COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	O75030	MITF	P31749	AKT1	S516	S511I	511	Missense	distal	-5	no	15.700	15.603	PhosphoSitePlus	COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	O75030	MITF	P31749	AKT1	S518	S512I	512	Missense	distal	-6	no	11.452	11.332	EPSD	COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	O75030	MITF	P31749	AKT1	S518	R513W	513	Missense	distal	-5	no	11.452	5.932	EPSD	COSMIC	7.780	Loss
AGC_Akt_AKT1_ST	O75030	MITF	P31749	AKT1	S518	T522M	522	Missense	distal	4	no	11.452	11.621	EPSD	COSMIC	7.780	Up-regulation
AGC_Akt_AKT1_ST	O75030	MITF	P31749	AKT1	S518	S518I	518	Missense	central	0	yes	11.452	0.000	EPSD	COSMIC	7.780	Loss
AGC_Akt_AKT1_ST	O75030	MITF	P31749	AKT1	S518	S511I	511	Missense	distal	-7	no	11.452	11.080	EPSD	COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	P51617	IRAK1	P31749	AKT1	T66	R61C	61	Missense	distal	-5	no	8.706	4.629	EPSD	COSMIC	7.780	Loss
AGC_Akt_AKT1_ST	P51617	IRAK1	P31749	AKT1	T66	C59W	59	Missense	distal	-7	no	8.706	8.761	EPSD	COSMIC	7.780	Up-regulation
AGC_Akt_AKT1_ST	P51617	IRAK1	P31749	AKT1	S120	I121L	121	Missense	proximal	1	no	11.741	12.088	EPSD	COSMIC	7.780	Up-regulation
AGC_Akt_AKT1_ST	P51617	IRAK1	P31749	AKT1	S120	T114A	114	Missense	distal	-6	no	11.741	11.655	EPSD	COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	P51617	IRAK1	P31749	AKT1	S371	R366C	366	Missense	distal	-5	no	9.035	4.958	EPSD	COSMIC;GDSC	7.780	Loss
AGC_Akt_AKT1_ST	P51617	IRAK1	P31749	AKT1	S371	G369V	369	Missense	proximal	-2	no	9.035	8.539	EPSD	COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	P51617	IRAK1	P31749	AKT1	T512	R507K	507	Missense	distal	-5	no	10.258	7.861	EPSD	COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	P51617	IRAK1	P31749	AKT1	T512	E516D	516	Missense	distal	4	no	10.258	10.404	EPSD	COSMIC	7.780	Up-regulation
AGC_Akt_AKT1_ST	P51617	IRAK1	P31749	AKT1	T512	Y515C	515	Missense	distal	3	no	10.258	10.150	EPSD	COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	P51617	IRAK1	P31749	AKT1	S556	G557V	557	Missense	proximal	1	no	11.753	12.057	EPSD	COSMIC	7.780	Up-regulation
AGC_Akt_AKT1_ST	P51617	IRAK1	P31749	AKT1	S556	S550R	550	Missense	distal	-6	no	11.753	11.788	EPSD	COSMIC	7.780	Up-regulation
AGC_Akt_AKT1_ST	P51617	IRAK1	P31749	AKT1	S556	P560A	560	Missense	distal	4	no	11.753	11.722	EPSD	COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	P62136	PPP1CA	P31749	AKT1	S48	I51T	51	Missense	distal	3	no	8.633	8.763	EPSD	COSMIC	7.780	Up-regulation
AGC_Akt_AKT1_ST	P62136	PPP1CA	P31749	AKT1	S48	P50H	50	Missense	proximal	2	no	8.633	8.436	EPSD	COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	P62136	PPP1CA	P31749	AKT1	S48	R43L	43	Missense	distal	-5	no	8.633	4.506	EPSD	COSMIC	7.780	Loss
AGC_Akt_AKT1_ST	P62136	PPP1CA	P31749	AKT1	S310	Q308L	308	Missense	proximal	-2	no	7.885	7.729	EPSD	COSMIC	7.780	Loss
AGC_Akt_AKT1_ST	P62136	PPP1CA	P31749	AKT1	S310	G304W	304	Missense	distal	-6	no	7.885	7.851	EPSD	COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	P62136	PPP1CA	P31749	AKT1	S310	Y306F	306	Missense	distal	-4	no	7.885	7.577	EPSD	COSMIC	7.780	Loss
AGC_Akt_AKT1_ST	P62136	PPP1CA	P31749	AKT1	S310	K303N	303	Missense	distal	-7	no	7.885	7.728	EPSD	COSMIC	7.780	Loss
AGC_Akt_AKT1_ST	P62136	PPP1CA	P31749	AKT1	S310	Y306C	306	Missense	distal	-4	no	7.885	7.152	EPSD	COSMIC	7.780	Loss
AGC_Akt_AKT1_ST	P62136	PPP1CA	P31749	AKT1	S310	G307W	307	Missense	distal	-3	no	7.885	5.701	EPSD	COSMIC	7.780	Loss
AGC_Akt_AKT1_ST	P62136	PPP1CA	P31749	AKT1	S310	G315W	315	Missense	distal	5	no	7.885	7.861	EPSD	COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	P62136	PPP1CA	P31749	AKT1	T320	P321T	321	Missense	proximal	1	no	13.114	13.463	PhosphoSitePlus	COSMIC	7.780	Up-regulation
AGC_Akt_AKT1_ST	P62136	PPP1CA	P31749	AKT1	T320	P322S	322	Missense	proximal	2	no	13.114	13.451	PhosphoSitePlus	COSMIC	7.780	Up-regulation
AGC_Akt_AKT1_ST	P62136	PPP1CA	P31749	AKT1	T320	R323H	323	Missense	distal	3	no	13.114	13.031	PhosphoSitePlus	COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	P62136	PPP1CA	P31749	AKT1	T320	A326T	326	Missense	distal	6	no	13.114	13.217	PhosphoSitePlus	COSMIC	7.780	Up-regulation
AGC_Akt_AKT1_ST	P62136	PPP1CA	P31749	AKT1	T320	G315W	315	Missense	distal	-5	no	13.114	11.659	PhosphoSitePlus	COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	P62136	PPP1CA	P31749	AKT1	S325	P321T	321	Missense	distal	-4	no	7.896	8.688	EPSD	COSMIC	7.780	Up-regulation
AGC_Akt_AKT1_ST	P62136	PPP1CA	P31749	AKT1	S325	P322S	322	Missense	distal	-3	no	7.896	6.759	EPSD	COSMIC	7.780	Loss
AGC_Akt_AKT1_ST	P62136	PPP1CA	P31749	AKT1	S325	A328V	328	Missense	distal	3	no	7.896	7.864	EPSD	COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	P62136	PPP1CA	P31749	AKT1	S325	R323H	323	Missense	proximal	-2	no	7.896	7.035	EPSD	COSMIC	7.780	Loss
AGC_Akt_AKT1_ST	P62136	PPP1CA	P31749	AKT1	S325	A326T	326	Missense	proximal	1	no	7.896	8.162	EPSD	COSMIC	7.780	Up-regulation
AGC_Akt_AKT1_ST	O75376	NCOR1	P31749	AKT1	S24	Y20F	20	Missense	distal	-4	no	8.966	8.658	EPSD	COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	O75376	NCOR1	P31749	AKT1	S24	R19H	19	Missense	distal	-5	no	8.966	5.871	EPSD	COSMIC	7.780	Loss
AGC_Akt_AKT1_ST	O75376	NCOR1	P31749	AKT1	S24	Y27N	27	Missense	distal	3	no	8.966	8.978	EPSD	COSMIC	7.780	Up-regulation
AGC_Akt_AKT1_ST	O75376	NCOR1	P31749	AKT1	S70	E74K	74	Missense	distal	4	no	11.234	11.133	EPSD	COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	O75376	NCOR1	P31749	AKT1	S79	E74K	74	Missense	distal	-5	no	6.157	7.855	EPSD	COSMIC	7.780	Gain
AGC_Akt_AKT1_ST	O75376	NCOR1	P31749	AKT1	S88	R81Q	81	Missense	distal	-7	no	11.655	11.461	EPSD	COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	O75376	NCOR1	P31749	AKT1	S88	R85T	85	Missense	distal	-3	no	11.655	4.634	EPSD	COSMIC	7.780	Loss
AGC_Akt_AKT1_ST	O75376	NCOR1	P31749	AKT1	S88	S88G	88	Missense	central	0	yes	11.655	0.000	EPSD	COSMIC	7.780	Loss
AGC_Akt_AKT1_ST	O75376	NCOR1	P31749	AKT1	S88	E90G	90	Missense	proximal	2	no	11.655	11.512	EPSD	COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	O75376	NCOR1	P31749	AKT1	S88	H93Y	93	Missense	distal	5	no	11.655	11.678	EPSD	COSMIC	7.780	Up-regulation
AGC_Akt_AKT1_ST	O75376	NCOR1	P31749	AKT1	S88	S88R	88	Missense	central	0	yes	11.655	0.000	EPSD	COSMIC	7.780	Loss
AGC_Akt_AKT1_ST	O75376	NCOR1	P31749	AKT1	S115	S115F	115	Missense	central	0	yes	9.262	0.000	EPSD	COSMIC	7.780	Loss
AGC_Akt_AKT1_ST	O75376	NCOR1	P31749	AKT1	S115	H118D	118	Missense	distal	3	no	9.262	9.250	EPSD	COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	O75376	NCOR1	P31749	AKT1	S115	R121C	121	Missense	distal	6	no	9.262	9.060	EPSD	COSMIC;GDSC;CCLE	7.780	Down-regulation
AGC_Akt_AKT1_ST	O75376	NCOR1	P31749	AKT1	S224	P226S	226	Missense	proximal	2	no	7.573	7.909	EPSD	COSMIC	7.780	Gain
AGC_Akt_AKT1_ST	O75376	NCOR1	P31749	AKT1	S224	P225T	225	Missense	proximal	1	no	7.573	7.921	EPSD	COSMIC	7.780	Gain
AGC_Akt_AKT1_ST	O75376	NCOR1	P31749	AKT1	S370	R365S	365	Missense	distal	-5	no	8.643	4.173	EPSD	COSMIC	7.780	Loss
AGC_Akt_AKT1_ST	O75376	NCOR1	P31749	AKT1	S370	G366A	366	Missense	distal	-4	no	8.643	8.650	EPSD	COSMIC	7.780	Up-regulation
AGC_Akt_AKT1_ST	O75376	NCOR1	P31749	AKT1	S370	A367G	367	Missense	distal	-3	no	8.643	8.190	EPSD	COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	O75376	NCOR1	P31749	AKT1	S401	L400I	400	Missense	proximal	-1	no	11.034	11.013	EPSD	COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	O75376	NCOR1	P31749	AKT1	S401	E394D	394	Missense	distal	-7	no	11.034	10.812	EPSD	COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	O75376	NCOR1	P31749	AKT1	T586	R581S	581	Missense	distal	-5	no	9.066	4.596	EPSD	COSMIC	7.780	Loss
AGC_Akt_AKT1_ST	O75376	NCOR1	P31749	AKT1	T586	R584L	584	Missense	proximal	-2	no	9.066	8.398	EPSD	COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	O75376	NCOR1	P31749	AKT1	T586	T590A	590	Missense	distal	4	no	9.066	9.196	EPSD	COSMIC	7.780	Up-regulation
AGC_Akt_AKT1_ST	O75376	NCOR1	P31749	AKT1	T590	R584L	584	Missense	distal	-6	no	12.112	12.027	EPSD	COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	O75376	NCOR1	P31749	AKT1	T590	T590A	590	Missense	central	0	yes	12.112	0.000	EPSD	COSMIC	7.780	Loss
AGC_Akt_AKT1_ST	O75376	NCOR1	P31749	AKT1	S875	A868V	868	Missense	distal	-7	no	8.222	8.093	EPSD	COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	O75376	NCOR1	P31749	AKT1	S875	Q874H	874	Missense	proximal	-1	no	8.222	8.209	EPSD	COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	O75376	NCOR1	P31749	AKT1	S875	P871S	871	Missense	distal	-4	no	8.222	8.958	EPSD	COSMIC	7.780	Up-regulation
AGC_Akt_AKT1_ST	O75376	NCOR1	P31749	AKT1	S875	T882M	882	Missense	distal	7	no	8.222	8.153	EPSD	COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	O75376	NCOR1	P31749	AKT1	S875	P873L	873	Missense	proximal	-2	no	8.222	8.189	EPSD	COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	O75376	NCOR1	P31749	AKT1	S875	S880G	880	Missense	distal	5	no	8.222	8.159	EPSD	COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	O75376	NCOR1	P31749	AKT1	S875	E872D	872	Missense	distal	-3	no	8.222	8.842	EPSD	COSMIC	7.780	Up-regulation
AGC_Akt_AKT1_ST	O75376	NCOR1	P31749	AKT1	T991	S990Y	990	Missense	proximal	-1	no	9.546	9.520	EPSD	COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	O75376	NCOR1	P31749	AKT1	T991	K998N	998	Missense	distal	7	no	9.546	9.510	EPSD	COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	O75376	NCOR1	P31749	AKT1	T991	R988I	988	Missense	distal	-3	no	9.546	2.465	EPSD	COSMIC	7.780	Loss
AGC_Akt_AKT1_ST	O75376	NCOR1	P31749	AKT1	T991	C994Y	994	Missense	distal	3	no	9.546	9.654	EPSD	COSMIC	7.780	Up-regulation
AGC_Akt_AKT1_ST	O75376	NCOR1	P31749	AKT1	S1151	S1157N	1157	Missense	distal	6	no	8.316	8.248	EPSD	COSMIC;CCLE	7.780	Down-regulation
AGC_Akt_AKT1_ST	O75376	NCOR1	P31749	AKT1	S1151	V1155M	1155	Missense	distal	4	no	8.316	8.299	EPSD	COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	O75376	NCOR1	P31749	AKT1	S1151	S1154P	1154	Missense	distal	3	no	8.316	8.234	EPSD	COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	O75376	NCOR1	P31749	AKT1	S1151	P1149S	1149	Missense	proximal	-2	no	8.316	9.140	EPSD	COSMIC	7.780	Up-regulation
AGC_Akt_AKT1_ST	O75376	NCOR1	P31749	AKT1	S1151	R1146Q	1146	Missense	distal	-5	no	8.316	4.088	EPSD	COSMIC	7.780	Loss
AGC_Akt_AKT1_ST	O75376	NCOR1	P31749	AKT1	S1206	K1207Q	1207	Missense	proximal	1	no	10.744	10.526	EPSD	COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	O75376	NCOR1	P31749	AKT1	S1206	A1204D	1204	Missense	proximal	-2	no	10.744	9.802	EPSD	COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	O75376	NCOR1	P31749	AKT1	S1206	E1202Q	1202	Missense	distal	-4	no	10.744	10.720	EPSD	COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	O75376	NCOR1	P31749	AKT1	S1206	E1203G	1203	Missense	distal	-3	no	10.744	10.559	EPSD	COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	O75376	NCOR1	P31749	AKT1	S1206	G1208S	1208	Missense	proximal	2	no	10.744	11.076	EPSD	COSMIC	7.780	Up-regulation
AGC_Akt_AKT1_ST	O75376	NCOR1	P31749	AKT1	T1232	R1233Q	1233	Missense	proximal	1	no	10.472	10.177	EPSD	COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	O75376	NCOR1	P31749	AKT1	T1232	R1229Q	1229	Missense	distal	-3	no	10.472	3.261	EPSD	COSMIC	7.780	Loss
AGC_Akt_AKT1_ST	O75376	NCOR1	P31749	AKT1	S1234	R1233Q	1233	Missense	proximal	-1	no	9.438	9.406	EPSD	COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	O75376	NCOR1	P31749	AKT1	S1234	R1229Q	1229	Missense	distal	-5	no	9.438	5.210	EPSD	COSMIC	7.780	Loss
AGC_Akt_AKT1_ST	O75376	NCOR1	P31749	AKT1	S1266	P1264S	1264	Missense	proximal	-2	no	7.124	7.948	EPSD	COSMIC	7.780	Gain
AGC_Akt_AKT1_ST	O75376	NCOR1	P31749	AKT1	S1307	E1309Q	1309	Missense	proximal	2	no	9.458	9.357	EPSD	COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	O75376	NCOR1	P31749	AKT1	S1307	R1302T	1302	Missense	distal	-5	no	9.458	5.728	EPSD	COSMIC	7.780	Loss
AGC_Akt_AKT1_ST	O75376	NCOR1	P31749	AKT1	S1307	D1310N	1310	Missense	distal	3	no	9.458	9.513	EPSD	COSMIC	7.780	Up-regulation
AGC_Akt_AKT1_ST	O75376	NCOR1	P31749	AKT1	S1307	F1308S	1308	Missense	proximal	1	no	9.458	9.440	EPSD	COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	O75376	NCOR1	P31749	AKT1	T1333	G1330R	1330	Missense	distal	-3	no	4.632	11.388	EPSD	COSMIC	7.780	Gain
AGC_Akt_AKT1_ST	O75376	NCOR1	P31749	AKT1	T1361	R1365C	1365	Missense	distal	4	no	8.177	8.511	EPSD	COSMIC	7.780	Up-regulation
AGC_Akt_AKT1_ST	O75376	NCOR1	P31749	AKT1	T1361	I1359M	1359	Missense	proximal	-2	no	8.177	8.579	EPSD	COSMIC	7.780	Up-regulation
AGC_Akt_AKT1_ST	O75376	NCOR1	P31749	AKT1	T1361	R1365Q	1365	Missense	distal	4	no	8.177	8.301	EPSD	COSMIC	7.780	Up-regulation
AGC_Akt_AKT1_ST	O75376	NCOR1	P31749	AKT1	S1450	T1449M	1449	Missense	proximal	-1	no	15.706	15.671	PhosphoSitePlus	COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	O75376	NCOR1	P31749	AKT1	S1450	S1450L	1450	Missense	central	0	yes	15.706	0.000	PhosphoSitePlus	COSMIC	7.780	Loss
AGC_Akt_AKT1_ST	O75376	NCOR1	P31749	AKT1	S1450	V1444A	1444	Missense	distal	-6	no	15.706	15.726	PhosphoSitePlus	COSMIC;GDSC;CCLE	7.780	Up-regulation
AGC_Akt_AKT1_ST	O75376	NCOR1	P31749	AKT1	S1450	S1453T	1453	Missense	distal	3	no	15.706	15.705	PhosphoSitePlus	COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	O75376	NCOR1	P31749	AKT1	S1450	R1447W	1447	Missense	distal	-3	no	15.706	6.765	PhosphoSitePlus	COSMIC	7.780	Loss
AGC_Akt_AKT1_ST	O75376	NCOR1	P31749	AKT1	S1487	M1492I	1492	Missense	distal	5	no	9.010	8.970	EPSD	COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	O75376	NCOR1	P31749	AKT1	S1487	A1481E	1481	Missense	distal	-6	no	9.010	9.019	EPSD	COSMIC	7.780	Up-regulation
AGC_Akt_AKT1_ST	O75376	NCOR1	P31749	AKT1	S1487	Q1489E	1489	Missense	proximal	2	no	9.010	9.111	EPSD	COSMIC	7.780	Up-regulation
AGC_Akt_AKT1_ST	O75376	NCOR1	P31749	AKT1	S1487	N1490S	1490	Missense	distal	3	no	9.010	9.067	EPSD	COSMIC	7.780	Up-regulation
AGC_Akt_AKT1_ST	O75376	NCOR1	P31749	AKT1	T1555	R1561W	1561	Missense	distal	6	no	10.415	10.257	EPSD	COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	O75376	NCOR1	P31749	AKT1	T1555	G1553A	1553	Missense	proximal	-2	no	10.415	10.657	EPSD	COSMIC	7.780	Up-regulation
AGC_Akt_AKT1_ST	O75376	NCOR1	P31749	AKT1	S1592	P1593S	1593	Missense	proximal	1	no	11.967	12.122	EPSD	COSMIC	7.780	Up-regulation
AGC_Akt_AKT1_ST	O75376	NCOR1	P31749	AKT1	S1592	S1599N	1599	Missense	distal	7	no	11.967	11.931	EPSD	COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	O75376	NCOR1	P31749	AKT1	S1636	P1641L	1641	Missense	distal	5	no	11.783	11.769	EPSD	COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	O75376	NCOR1	P31749	AKT1	S1636	G1643S	1643	Missense	distal	7	no	11.783	11.856	EPSD	COSMIC	7.780	Up-regulation
AGC_Akt_AKT1_ST	O75376	NCOR1	P31749	AKT1	S1636	G1634E	1634	Missense	proximal	-2	no	11.783	12.069	EPSD	COSMIC	7.780	Up-regulation
AGC_Akt_AKT1_ST	O75376	NCOR1	P31749	AKT1	S1733	A1732V	1732	Missense	proximal	-1	no	7.840	7.826	EPSD	COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	O75376	NCOR1	P31749	AKT1	S1733	S1733Y	1733	Missense	central	0	yes	7.840	0.000	EPSD	COSMIC	7.780	Loss
AGC_Akt_AKT1_ST	O75376	NCOR1	P31749	AKT1	S1733	R1728W	1728	Missense	distal	-5	no	7.840	2.320	EPSD	COSMIC;GDSC;CCLE	7.780	Loss
AGC_Akt_AKT1_ST	O75376	NCOR1	P31749	AKT1	S1733	R1728Q	1728	Missense	distal	-5	no	7.840	3.613	EPSD	COSMIC;GDSC;CCLE	7.780	Loss
AGC_Akt_AKT1_ST	O75376	NCOR1	P31749	AKT1	S1733	P1740T	1740	Missense	distal	7	no	7.840	7.909	EPSD	COSMIC	7.780	Up-regulation
AGC_Akt_AKT1_ST	O75376	NCOR1	P31749	AKT1	S1733	D1735N	1735	Missense	proximal	2	no	7.840	8.170	EPSD	COSMIC	7.780	Up-regulation
AGC_Akt_AKT1_ST	O75376	NCOR1	P31749	AKT1	S1742	R1747Q	1747	Missense	distal	5	no	9.780	9.729	EPSD	COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	O75376	NCOR1	P31749	AKT1	S1742	P1740T	1740	Missense	proximal	-2	no	9.780	10.538	EPSD	COSMIC	7.780	Up-regulation
AGC_Akt_AKT1_ST	O75376	NCOR1	P31749	AKT1	S1742	D1735N	1735	Missense	distal	-7	no	9.780	10.037	EPSD	COSMIC	7.780	Up-regulation
AGC_Akt_AKT1_ST	O75376	NCOR1	P31749	AKT1	S1742	S1742L	1742	Missense	central	0	yes	9.780	0.000	EPSD	COSMIC	7.780	Loss
AGC_Akt_AKT1_ST	O75376	NCOR1	P31749	AKT1	S1750	R1747Q	1747	Missense	distal	-3	no	11.999	4.788	EPSD	COSMIC	7.780	Loss
AGC_Akt_AKT1_ST	O75376	NCOR1	P31749	AKT1	S1750	R1755H	1755	Missense	distal	5	no	11.999	11.925	EPSD	COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	O75376	NCOR1	P31749	AKT1	S1750	S1750C	1750	Missense	central	0	yes	11.999	0.000	EPSD	COSMIC	7.780	Loss
AGC_Akt_AKT1_ST	O75376	NCOR1	P31749	AKT1	S1750	P1757S	1757	Missense	distal	7	no	11.999	12.058	EPSD	COSMIC	7.780	Up-regulation
AGC_Akt_AKT1_ST	O75376	NCOR1	P31749	AKT1	S1758	S1758L	1758	Missense	central	0	yes	11.618	0.000	EPSD	COSMIC	7.780	Loss
AGC_Akt_AKT1_ST	O75376	NCOR1	P31749	AKT1	S1758	R1755H	1755	Missense	distal	-3	no	11.618	6.919	EPSD	COSMIC	7.780	Loss
AGC_Akt_AKT1_ST	O75376	NCOR1	P31749	AKT1	S1758	S1758P	1758	Missense	central	0	yes	11.618	0.000	EPSD	COSMIC	7.780	Loss
AGC_Akt_AKT1_ST	O75376	NCOR1	P31749	AKT1	S1758	P1757S	1757	Missense	proximal	-1	no	11.618	11.647	EPSD	COSMIC	7.780	Up-regulation
AGC_Akt_AKT1_ST	O75376	NCOR1	P31749	AKT1	S1758	V1761I	1761	Missense	distal	3	no	11.618	11.577	EPSD	COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	O75376	NCOR1	P31749	AKT1	S1760	S1758L	1758	Missense	proximal	-2	no	9.917	9.060	EPSD	COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	O75376	NCOR1	P31749	AKT1	S1760	R1755H	1755	Missense	distal	-5	no	9.917	6.822	EPSD	COSMIC	7.780	Loss
AGC_Akt_AKT1_ST	O75376	NCOR1	P31749	AKT1	S1760	S1758P	1758	Missense	proximal	-2	no	9.917	9.092	EPSD	COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	O75376	NCOR1	P31749	AKT1	S1760	P1757S	1757	Missense	distal	-3	no	9.917	8.780	EPSD	COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	O75376	NCOR1	P31749	AKT1	S1760	V1761I	1761	Missense	proximal	1	no	9.917	9.669	EPSD	COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	O75376	NCOR1	P31749	AKT1	S1955	R1950H	1950	Missense	distal	-5	no	8.599	5.504	EPSD	COSMIC;GDSC;CCLE	7.780	Loss
AGC_Akt_AKT1_ST	O75376	NCOR1	P31749	AKT1	S1955	D1956V	1956	Missense	proximal	1	no	8.599	8.811	EPSD	COSMIC;GDSC;CCLE	7.780	Up-regulation
AGC_Akt_AKT1_ST	O75376	NCOR1	P31749	AKT1	T1968	D1971N	1971	Missense	distal	3	no	9.539	9.595	EPSD	COSMIC	7.780	Up-regulation
AGC_Akt_AKT1_ST	O75376	NCOR1	P31749	AKT1	T1968	A1972S	1972	Missense	distal	4	no	9.539	9.415	EPSD	COSMIC;CCLE	7.780	Down-regulation
AGC_Akt_AKT1_ST	O75376	NCOR1	P31749	AKT1	T1968	R1965S	1965	Missense	distal	-3	no	9.539	1.763	EPSD	COSMIC	7.780	Loss
AGC_Akt_AKT1_ST	O75376	NCOR1	P31749	AKT1	S1970	D1971N	1971	Missense	proximal	1	no	9.236	9.360	EPSD	COSMIC	7.780	Up-regulation
AGC_Akt_AKT1_ST	O75376	NCOR1	P31749	AKT1	S1970	A1972S	1972	Missense	proximal	2	no	9.236	9.612	EPSD	COSMIC;CCLE	7.780	Up-regulation
AGC_Akt_AKT1_ST	O75376	NCOR1	P31749	AKT1	S1970	R1965S	1965	Missense	distal	-5	no	9.236	4.766	EPSD	COSMIC	7.780	Loss
AGC_Akt_AKT1_ST	O75376	NCOR1	P31749	AKT1	S2023	R2018T	2018	Missense	distal	-5	no	8.368	4.638	EPSD	COSMIC	7.780	Loss
AGC_Akt_AKT1_ST	O75376	NCOR1	P31749	AKT1	S2023	H2016N	2016	Missense	distal	-7	no	8.368	8.499	EPSD	COSMIC	7.780	Up-regulation
AGC_Akt_AKT1_ST	O75376	NCOR1	P31749	AKT1	S2023	Y2017C	2017	Missense	distal	-6	no	8.368	8.281	EPSD	COSMIC;CCLE	7.780	Down-regulation
AGC_Akt_AKT1_ST	O75376	NCOR1	P31749	AKT1	S2023	R2018Q	2018	Missense	distal	-5	no	8.368	4.141	EPSD	COSMIC	7.780	Loss
AGC_Akt_AKT1_ST	O75376	NCOR1	P31749	AKT1	S2023	S2025F	2025	Missense	proximal	2	no	8.368	7.791	EPSD	COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	O75376	NCOR1	P31749	AKT1	T2050	A2052V	2052	Missense	proximal	2	no	10.037	9.874	EPSD	COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	O75376	NCOR1	P31749	AKT1	T2050	D2053G	2053	Missense	distal	3	no	10.037	10.057	EPSD	COSMIC	7.780	Up-regulation
AGC_Akt_AKT1_ST	O75376	NCOR1	P31749	AKT1	T2050	T2050K	2050	Missense	central	0	yes	10.037	0.000	EPSD	COSMIC	7.780	Loss
AGC_Akt_AKT1_ST	O75376	NCOR1	P31749	AKT1	T2050	T2045I	2045	Missense	distal	-5	no	10.037	9.199	EPSD	COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	O75376	NCOR1	P31749	AKT1	T2050	R2047W	2047	Missense	distal	-3	no	10.037	1.096	EPSD	COSMIC	7.780	Loss
AGC_Akt_AKT1_ST	O75376	NCOR1	P31749	AKT1	S2070	S2070L	2070	Missense	central	0	yes	8.269	0.000	EPSD	COSMIC;CCLE	7.780	Loss
AGC_Akt_AKT1_ST	O75376	NCOR1	P31749	AKT1	T2097	E2104K	2104	Missense	distal	7	no	10.708	10.742	EPSD	COSMIC	7.780	Up-regulation
AGC_Akt_AKT1_ST	O75376	NCOR1	P31749	AKT1	T2097	R2100H	2100	Missense	distal	3	no	10.708	10.624	EPSD	COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	O75376	NCOR1	P31749	AKT1	T2097	T2091A	2091	Missense	distal	-6	no	10.708	10.622	EPSD	COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	O75376	NCOR1	P31749	AKT1	T2097	N2099H	2099	Missense	proximal	2	no	10.708	10.444	EPSD	COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	O75376	NCOR1	P31749	AKT1	S2117	R2118C	2118	Missense	proximal	1	no	11.593	11.065	EPSD	COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	O75376	NCOR1	P31749	AKT1	S2117	L2124V	2124	Missense	distal	7	no	11.593	11.604	EPSD	COSMIC	7.780	Up-regulation
AGC_Akt_AKT1_ST	O75376	NCOR1	P31749	AKT1	S2117	H2111L	2111	Missense	distal	-6	no	11.593	11.627	EPSD	COSMIC	7.780	Up-regulation
AGC_Akt_AKT1_ST	O75376	NCOR1	P31749	AKT1	S2117	Q2113E	2113	Missense	distal	-4	no	11.593	11.617	EPSD	COSMIC	7.780	Up-regulation
AGC_Akt_AKT1_ST	O75376	NCOR1	P31749	AKT1	S2117	L2124I	2124	Missense	distal	7	no	11.593	11.562	EPSD	COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	O75376	NCOR1	P31749	AKT1	S2117	H2112N	2112	Missense	distal	-5	no	11.593	10.203	EPSD	COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	O75376	NCOR1	P31749	AKT1	S2140	E2138K	2138	Missense	proximal	-2	no	7.139	7.799	EPSD	COSMIC	7.780	Gain
AGC_Akt_AKT1_ST	O75376	NCOR1	P31749	AKT1	S2144	S2143L	2143	Missense	proximal	-1	no	10.794	10.765	EPSD	COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	O75376	NCOR1	P31749	AKT1	S2144	H2141Y	2141	Missense	distal	-3	no	10.794	7.903	EPSD	COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	O75376	NCOR1	P31749	AKT1	S2144	E2145K	2145	Missense	proximal	1	no	10.794	10.957	EPSD	COSMIC	7.780	Up-regulation
AGC_Akt_AKT1_ST	O75376	NCOR1	P31749	AKT1	S2144	V2142I	2142	Missense	proximal	-2	no	10.794	10.743	EPSD	COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	O75376	NCOR1	P31749	AKT1	S2144	E2138K	2138	Missense	distal	-6	no	10.794	10.860	EPSD	COSMIC	7.780	Up-regulation
AGC_Akt_AKT1_ST	O75376	NCOR1	P31749	AKT1	S2144	E2148K	2148	Missense	distal	4	no	10.794	10.693	EPSD	COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	O75376	NCOR1	P31749	AKT1	S2184	P2185S	2185	Missense	proximal	1	no	9.265	9.420	EPSD	COSMIC	7.780	Up-regulation
AGC_Akt_AKT1_ST	O75376	NCOR1	P31749	AKT1	S2184	R2183C	2183	Missense	proximal	-1	no	9.265	9.194	EPSD	COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	O75376	NCOR1	P31749	AKT1	S2184	S2187N	2187	Missense	distal	3	no	9.265	9.209	EPSD	COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	O75376	NCOR1	P31749	AKT1	S2184	S2184F	2184	Missense	central	0	yes	9.265	0.000	EPSD	COSMIC	7.780	Loss
AGC_Akt_AKT1_ST	O75376	NCOR1	P31749	AKT1	S2184	A2182T	2182	Missense	proximal	-2	no	9.265	9.650	EPSD	COSMIC	7.780	Up-regulation
AGC_Akt_AKT1_ST	O75376	NCOR1	P31749	AKT1	S2184	E2177Q	2177	Missense	distal	-7	no	9.265	9.276	EPSD	COSMIC	7.780	Up-regulation
AGC_Akt_AKT1_ST	O75376	NCOR1	P31749	AKT1	S2219	M2226V	2226	Missense	distal	7	no	8.285	8.288	EPSD	COSMIC	7.780	Up-regulation
AGC_Akt_AKT1_ST	O75376	NCOR1	P31749	AKT1	S2253	P2257H	2257	Missense	distal	4	no	11.398	11.438	EPSD	COSMIC	7.780	Up-regulation
AGC_Akt_AKT1_ST	O75376	NCOR1	P31749	AKT1	S2253	S2246L	2246	Missense	distal	-7	no	11.398	11.164	EPSD	COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	O75376	NCOR1	P31749	AKT1	S2253	S2253Y	2253	Missense	central	0	yes	11.398	0.000	EPSD	COSMIC;GDSC;CCLE	7.780	Loss
AGC_Akt_AKT1_ST	O75376	NCOR1	P31749	AKT1	S2328	S2332L	2332	Missense	distal	4	no	8.086	8.275	EPSD	COSMIC	7.780	Up-regulation
AGC_Akt_AKT1_ST	O75376	NCOR1	P31749	AKT1	S2328	K2323Q	2323	Missense	distal	-5	no	8.086	6.256	EPSD	COSMIC	7.780	Loss
AGC_Akt_AKT1_ST	O75376	NCOR1	P31749	AKT1	S2328	K2325N	2325	Missense	distal	-3	no	8.086	5.130	EPSD	COSMIC	7.780	Loss
AGC_Akt_AKT1_ST	O75376	NCOR1	P31749	AKT1	S2328	I2327M	2327	Missense	proximal	-1	no	8.086	8.107	EPSD	COSMIC	7.780	Up-regulation
AGC_Akt_AKT1_ST	O75376	NCOR1	P31749	AKT1	S2352	R2349W	2349	Missense	distal	-3	no	11.251	2.310	EPSD	COSMIC	7.780	Loss
AGC_Akt_AKT1_ST	O75376	NCOR1	P31749	AKT1	S2352	E2348K	2348	Missense	distal	-4	no	11.251	11.835	EPSD	COSMIC	7.780	Up-regulation
AGC_Akt_AKT1_ST	O75376	NCOR1	P31749	AKT1	S2352	S2355P	2355	Missense	distal	3	no	11.251	11.169	EPSD	COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	O75376	NCOR1	P31749	AKT1	S2377	P2384L	2384	Missense	distal	7	no	9.488	9.480	EPSD	COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	O75376	NCOR1	P31749	AKT1	S2394	P2387S	2387	Missense	distal	-7	no	11.708	11.902	EPSD	COSMIC	7.780	Up-regulation
AGC_Akt_AKT1_ST	O75376	NCOR1	P31749	AKT1	S2394	T2396S	2396	Missense	proximal	2	no	11.708	11.783	EPSD	COSMIC	7.780	Up-regulation
AGC_Akt_AKT1_ST	O75376	NCOR1	P31749	AKT1	S2394	R2391W	2391	Missense	distal	-3	no	11.708	2.768	EPSD	COSMIC	7.780	Loss
AGC_Akt_AKT1_ST	O75376	NCOR1	P31749	AKT1	T2396	R2391W	2391	Missense	distal	-5	no	9.216	3.696	EPSD	COSMIC	7.780	Loss
AGC_Akt_AKT1_ST	O75376	NCOR1	P31749	AKT1	S2429	E2423G	2423	Missense	distal	-6	no	7.847	7.814	EPSD	COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	O75376	NCOR1	P31749	AKT1	S2429	E2423A	2423	Missense	distal	-6	no	7.847	7.838	EPSD	COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	P12755	SKI	P31749	AKT1	T103	C101F	101	Missense	proximal	-2	no	9.827	10.613	EPSD	COSMIC	7.780	Up-regulation
AGC_Akt_AKT1_ST	P12755	SKI	P31749	AKT1	S325	P328H	328	Missense	distal	3	no	8.452	8.433	EPSD	COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	P12755	SKI	P31749	AKT1	S325	S326F	326	Missense	proximal	1	no	8.452	8.469	EPSD	COSMIC	7.780	Up-regulation
AGC_Akt_AKT1_ST	P12755	SKI	P31749	AKT1	S326	P328H	328	Missense	proximal	2	no	10.792	10.595	EPSD	COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	P12755	SKI	P31749	AKT1	S326	S326F	326	Missense	central	0	yes	10.792	0.000	EPSD	COSMIC	7.780	Loss
AGC_Akt_AKT1_ST	P12755	SKI	P31749	AKT1	S383	A388V	388	Missense	distal	5	no	10.698	10.690	EPSD	COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	P12755	SKI	P31749	AKT1	S383	A385S	385	Missense	proximal	2	no	10.698	11.074	EPSD	COSMIC	7.780	Up-regulation
AGC_Akt_AKT1_ST	P12755	SKI	P31749	AKT1	S383	R380Q	380	Missense	distal	-3	no	10.698	3.487	EPSD	COSMIC	7.780	Loss
AGC_Akt_AKT1_ST	P12755	SKI	P31749	AKT1	S720	G722V	722	Missense	proximal	2	no	8.380	8.174	EPSD	COSMIC;CCLE	7.780	Down-regulation
AGC_Akt_AKT1_ST	P05106	ITGB3	P31749	AKT1	T767	N769S	769	Missense	proximal	2	no	9.579	9.847	EPSD	COSMIC	7.780	Up-regulation
AGC_Akt_AKT1_ST	P05106	ITGB3	P31749	AKT1	T777	A776V	776	Missense	proximal	-1	no	9.005	8.991	EPSD	COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	P05106	ITGB3	P31749	AKT1	T777	E775K	775	Missense	proximal	-2	no	9.005	9.664	EPSD	COSMIC	7.780	Up-regulation
AGC_Akt_AKT1_ST	P05106	ITGB3	P31749	AKT1	S778	A776V	776	Missense	proximal	-2	no	9.215	8.477	EPSD	COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	P05106	ITGB3	P31749	AKT1	S778	E775K	775	Missense	distal	-3	no	9.215	11.266	EPSD	COSMIC	7.780	Up-regulation
AGC_Akt_AKT1_ST	P05106	ITGB3	P31749	AKT1	T779	A776V	776	Missense	distal	-3	no	8.504	7.941	PhosphoSitePlus	COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	P05106	ITGB3	P31749	AKT1	T779	E775K	775	Missense	distal	-4	no	8.504	9.087	PhosphoSitePlus	COSMIC	7.780	Up-regulation
AGC_Akt_AKT1_ST	Q9BXL7	CARD11	P31749	AKT1	S34	H31R	31	Missense	distal	-3	no	7.263	11.962	EPSD	COSMIC	7.780	Gain
AGC_Akt_AKT1_ST	Q9BXL7	CARD11	P31749	AKT1	S116	T112I	112	Missense	distal	-4	no	12.134	10.697	EPSD	COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	Q9BXL7	CARD11	P31749	AKT1	S116	G123D	123	Missense	distal	7	no	12.134	12.131	EPSD	COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	Q9BXL7	CARD11	P31749	AKT1	S116	S116P	116	Missense	central	0	yes	12.134	0.000	EPSD	COSMIC	7.780	Loss
AGC_Akt_AKT1_ST	Q9BXL7	CARD11	P31749	AKT1	S116	F115L	115	Missense	proximal	-1	no	12.134	12.140	EPSD	COSMIC	7.780	Up-regulation
AGC_Akt_AKT1_ST	Q9BXL7	CARD11	P31749	AKT1	S116	T117A	117	Missense	proximal	1	no	12.134	11.867	EPSD	COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	Q9BXL7	CARD11	P31749	AKT1	S116	R113Q	113	Missense	distal	-3	no	12.134	4.923	EPSD	COSMIC	7.780	Loss
AGC_Akt_AKT1_ST	Q9BXL7	CARD11	P31749	AKT1	S116	F115S	115	Missense	proximal	-1	no	12.134	12.169	EPSD	COSMIC	7.780	Up-regulation
AGC_Akt_AKT1_ST	Q9BXL7	CARD11	P31749	AKT1	S116	R114K	114	Missense	proximal	-2	no	12.134	12.574	EPSD	COSMIC;GDSC;CCLE	7.780	Up-regulation
AGC_Akt_AKT1_ST	Q9BXL7	CARD11	P31749	AKT1	S116	G123C	123	Missense	distal	7	no	12.134	12.085	EPSD	COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	Q9BXL7	CARD11	P31749	AKT1	T117	T112I	112	Missense	distal	-5	no	10.169	9.331	EPSD	COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	Q9BXL7	CARD11	P31749	AKT1	T117	G123D	123	Missense	distal	6	no	10.169	10.125	EPSD	COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	Q9BXL7	CARD11	P31749	AKT1	T117	S116P	116	Missense	proximal	-1	no	10.169	10.140	EPSD	COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	Q9BXL7	CARD11	P31749	AKT1	T117	F115L	115	Missense	proximal	-2	no	10.169	10.179	EPSD	COSMIC	7.780	Up-regulation
AGC_Akt_AKT1_ST	Q9BXL7	CARD11	P31749	AKT1	T117	T117A	117	Missense	central	0	yes	10.169	0.000	EPSD	COSMIC	7.780	Loss
AGC_Akt_AKT1_ST	Q9BXL7	CARD11	P31749	AKT1	T117	R113Q	113	Missense	distal	-4	no	10.169	9.548	EPSD	COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	Q9BXL7	CARD11	P31749	AKT1	T117	F115S	115	Missense	proximal	-2	no	10.169	11.035	EPSD	COSMIC	7.780	Up-regulation
AGC_Akt_AKT1_ST	Q9BXL7	CARD11	P31749	AKT1	T117	R114K	114	Missense	distal	-3	no	10.169	5.648	EPSD	COSMIC;GDSC;CCLE	7.780	Loss
AGC_Akt_AKT1_ST	Q9BXL7	CARD11	P31749	AKT1	T117	G123C	123	Missense	distal	6	no	10.169	10.071	EPSD	COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	Q9BXL7	CARD11	P31749	AKT1	S212	K215M	215	Missense	distal	3	no	9.759	9.671	EPSD	COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	Q9BXL7	CARD11	P31749	AKT1	S212	A205V	205	Missense	distal	-7	no	9.759	9.630	EPSD	COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	Q9BXL7	CARD11	P31749	AKT1	S212	A209S	209	Missense	distal	-3	no	9.759	8.285	EPSD	COSMIC;GDSC;CCLE	7.780	Down-regulation
AGC_Akt_AKT1_ST	Q9BXL7	CARD11	P31749	AKT1	S212	M217L	217	Missense	distal	5	no	9.759	9.749	EPSD	COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	Q9BXL7	CARD11	P31749	AKT1	S212	E214D	214	Missense	proximal	2	no	9.759	9.349	EPSD	COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	Q9BXL7	CARD11	P31749	AKT1	S212	E213K	213	Missense	proximal	1	no	9.759	9.922	EPSD	COSMIC	7.780	Up-regulation
AGC_Akt_AKT1_ST	Q9BXL7	CARD11	P31749	AKT1	S439	E432K	432	Missense	distal	-7	no	12.607	12.799	EPSD	COSMIC	7.780	Up-regulation
AGC_Akt_AKT1_ST	Q9BXL7	CARD11	P31749	AKT1	S439	D441N	441	Missense	proximal	2	no	12.607	12.937	EPSD	COSMIC	7.780	Up-regulation
AGC_Akt_AKT1_ST	Q9BXL7	CARD11	P31749	AKT1	S439	N444K	444	Missense	distal	5	no	12.607	12.642	EPSD	COSMIC	7.780	Up-regulation
AGC_Akt_AKT1_ST	Q9BXL7	CARD11	P31749	AKT1	S439	R436W	436	Missense	distal	-3	no	12.607	3.666	EPSD	COSMIC	7.780	Loss
AGC_Akt_AKT1_ST	Q9BXL7	CARD11	P31749	AKT1	S439	R437C	437	Missense	proximal	-2	no	12.607	11.143	EPSD	COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	Q9BXL7	CARD11	P31749	AKT1	S439	R436Q	436	Missense	distal	-3	no	12.607	5.395	EPSD	COSMIC;GDSC;CCLE	7.780	Loss
AGC_Akt_AKT1_ST	Q9BXL7	CARD11	P31749	AKT1	S439	S439F	439	Missense	central	0	yes	12.607	0.000	EPSD	COSMIC	7.780	Loss
AGC_Akt_AKT1_ST	Q9BXL7	CARD11	P31749	AKT1	S442	D441N	441	Missense	proximal	-1	no	8.450	8.480	EPSD	COSMIC	7.780	Up-regulation
AGC_Akt_AKT1_ST	Q9BXL7	CARD11	P31749	AKT1	S442	N444K	444	Missense	proximal	2	no	8.450	8.736	EPSD	COSMIC	7.780	Up-regulation
AGC_Akt_AKT1_ST	Q9BXL7	CARD11	P31749	AKT1	S442	R436W	436	Missense	distal	-6	no	8.450	8.303	EPSD	COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	Q9BXL7	CARD11	P31749	AKT1	S442	R437C	437	Missense	distal	-5	no	8.450	4.374	EPSD	COSMIC	7.780	Loss
AGC_Akt_AKT1_ST	Q9BXL7	CARD11	P31749	AKT1	S442	R436Q	436	Missense	distal	-6	no	8.450	8.366	EPSD	COSMIC;GDSC;CCLE	7.780	Down-regulation
AGC_Akt_AKT1_ST	Q9BXL7	CARD11	P31749	AKT1	S442	S439F	439	Missense	distal	-3	no	8.450	10.632	EPSD	COSMIC	7.780	Up-regulation
AGC_Akt_AKT1_ST	Q9BXL7	CARD11	P31749	AKT1	T456	P454S	454	Missense	proximal	-2	no	7.355	8.180	EPSD	COSMIC	7.780	Gain
AGC_Akt_AKT1_ST	Q9BXL7	CARD11	P31749	AKT1	T456	N452S	452	Missense	distal	-4	no	7.355	7.922	EPSD	COSMIC	7.780	Gain
AGC_Akt_AKT1_ST	Q9BXL7	CARD11	P31749	AKT1	S512	R509I	509	Missense	distal	-3	no	11.042	3.961	EPSD	COSMIC	7.780	Loss
AGC_Akt_AKT1_ST	Q9BXL7	CARD11	P31749	AKT1	S512	P513F	513	Missense	proximal	1	no	11.042	11.215	EPSD	COSMIC	7.780	Up-regulation
AGC_Akt_AKT1_ST	Q9BXL7	CARD11	P31749	AKT1	S512	P513S	513	Missense	proximal	1	no	11.042	11.197	EPSD	COSMIC	7.780	Up-regulation
AGC_Akt_AKT1_ST	Q9BXL7	CARD11	P31749	AKT1	S512	S512F	512	Missense	central	0	yes	11.042	0.000	EPSD	COSMIC	7.780	Loss
AGC_Akt_AKT1_ST	Q9BXL7	CARD11	P31749	AKT1	S512	P513L	513	Missense	proximal	1	no	11.042	11.296	EPSD	COSMIC	7.780	Up-regulation
AGC_Akt_AKT1_ST	Q9BXL7	CARD11	P31749	AKT1	S512	P513H	513	Missense	proximal	1	no	11.042	11.020	EPSD	COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	Q9BXL7	CARD11	P31749	AKT1	S512	A510V	510	Missense	proximal	-2	no	11.042	10.304	EPSD	COSMIC;GDSC;CCLE	7.780	Down-regulation
AGC_Akt_AKT1_ST	Q9BXL7	CARD11	P31749	AKT1	S515	S512F	512	Missense	distal	-3	no	5.725	7.907	EPSD	COSMIC	7.780	Gain
AGC_Akt_AKT1_ST	Q9BXL7	CARD11	P31749	AKT1	T545	G540R	540	Missense	distal	-5	no	5.253	9.317	EPSD	COSMIC;GDSC	7.780	Gain
AGC_Akt_AKT1_ST	Q9BXL7	CARD11	P31749	AKT1	S558	R557S	557	Missense	proximal	-1	no	11.722	11.711	EPSD;PhosphoSitePlus	COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	Q9BXL7	CARD11	P31749	AKT1	S558	P554S	554	Missense	distal	-4	no	11.722	12.458	EPSD;PhosphoSitePlus	COSMIC	7.780	Up-regulation
AGC_Akt_AKT1_ST	Q9BXL7	CARD11	P31749	AKT1	S558	A565V	565	Missense	distal	7	no	11.722	11.717	EPSD;PhosphoSitePlus	COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	Q9BXL7	CARD11	P31749	AKT1	S558	P553T	553	Missense	distal	-5	no	11.722	12.002	EPSD;PhosphoSitePlus	COSMIC	7.780	Up-regulation
AGC_Akt_AKT1_ST	Q9BXL7	CARD11	P31749	AKT1	S558	A565T	565	Missense	distal	7	no	11.722	11.782	EPSD;PhosphoSitePlus	COSMIC	7.780	Up-regulation
AGC_Akt_AKT1_ST	Q9BXL7	CARD11	P31749	AKT1	S558	S559C	559	Missense	proximal	1	no	11.722	11.338	EPSD;PhosphoSitePlus	COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	Q9BXL7	CARD11	P31749	AKT1	S562	G569E	569	Missense	distal	7	no	7.778	7.818	EPSD	COSMIC	7.780	Gain
AGC_Akt_AKT1_ST	Q9BXL7	CARD11	P31749	AKT1	S562	P568Q	568	Missense	distal	6	no	7.778	7.800	EPSD	COSMIC	7.780	Gain
AGC_Akt_AKT1_ST	Q9BXL7	CARD11	P31749	AKT1	S562	P567S	567	Missense	distal	5	no	7.778	7.831	EPSD	COSMIC	7.780	Gain
AGC_Akt_AKT1_ST	Q9BXL7	CARD11	P31749	AKT1	S562	A565T	565	Missense	distal	3	no	7.778	7.835	EPSD	COSMIC	7.780	Gain
AGC_Akt_AKT1_ST	Q9BXL7	CARD11	P31749	AKT1	S562	S559C	559	Missense	distal	-3	no	7.778	9.381	EPSD	COSMIC	7.780	Gain
AGC_Akt_AKT1_ST	Q9BXL7	CARD11	P31749	AKT1	T586	P582S	582	Missense	distal	-4	no	7.247	7.983	EPSD	COSMIC	7.780	Gain
AGC_Akt_AKT1_ST	Q9BXL7	CARD11	P31749	AKT1	S644	L645P	645	Missense	proximal	1	no	12.029	11.776	EPSD;PhosphoSitePlus	COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	Q9BXL7	CARD11	P31749	AKT1	S644	L645Q	645	Missense	proximal	1	no	12.029	11.781	EPSD;PhosphoSitePlus	COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	Q9BXL7	CARD11	P31749	AKT1	S644	F649S	649	Missense	distal	5	no	12.029	12.102	EPSD;PhosphoSitePlus	COSMIC	7.780	Up-regulation
AGC_Akt_AKT1_ST	Q9BXL7	CARD11	P31749	AKT1	S644	M639V	639	Missense	distal	-5	no	12.029	12.237	EPSD;PhosphoSitePlus	COSMIC	7.780	Up-regulation
AGC_Akt_AKT1_ST	Q9BXL7	CARD11	P31749	AKT1	S644	R647S	647	Missense	distal	3	no	12.029	12.046	EPSD;PhosphoSitePlus	COSMIC	7.780	Up-regulation
AGC_Akt_AKT1_ST	Q9BXL7	CARD11	P31749	AKT1	S652	T654I	654	Missense	proximal	2	no	10.482	9.900	PhosphoSitePlus;EPSD	COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	Q9BXL7	CARD11	P31749	AKT1	S652	L645P	645	Missense	distal	-7	no	10.482	10.521	PhosphoSitePlus;EPSD	COSMIC	7.780	Up-regulation
AGC_Akt_AKT1_ST	Q9BXL7	CARD11	P31749	AKT1	S652	L645Q	645	Missense	distal	-7	no	10.482	10.577	PhosphoSitePlus;EPSD	COSMIC	7.780	Up-regulation
AGC_Akt_AKT1_ST	Q9BXL7	CARD11	P31749	AKT1	S652	F649S	649	Missense	distal	-3	no	10.482	8.300	PhosphoSitePlus;EPSD	COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	Q9BXL7	CARD11	P31749	AKT1	S652	R647S	647	Missense	distal	-5	no	10.482	6.011	PhosphoSitePlus;EPSD	COSMIC	7.780	Loss
AGC_Akt_AKT1_ST	Q9BXL7	CARD11	P31749	AKT1	S655	T654I	654	Missense	proximal	-1	no	7.875	7.819	EPSD	COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	Q9BXL7	CARD11	P31749	AKT1	S655	R660L	660	Missense	distal	5	no	7.875	7.801	EPSD	COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	Q9BXL7	CARD11	P31749	AKT1	S655	R660W	660	Missense	distal	5	no	7.875	7.780	EPSD	COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	Q9BXL7	CARD11	P31749	AKT1	S655	R660Q	660	Missense	distal	5	no	7.875	7.824	EPSD	COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	Q9BXL7	CARD11	P31749	AKT1	S655	F649S	649	Missense	distal	-6	no	7.875	7.949	EPSD	COSMIC	7.780	Up-regulation
AGC_Akt_AKT1_ST	Q9BXL7	CARD11	P31749	AKT1	T871	L878F	878	Missense	distal	7	no	8.814	8.806	EPSD	COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	Q9BXL7	CARD11	P31749	AKT1	T871	R866Q	866	Missense	distal	-5	no	8.814	4.586	EPSD	COSMIC	7.780	Loss
AGC_Akt_AKT1_ST	Q9BXL7	CARD11	P31749	AKT1	T871	L868F	868	Missense	distal	-3	no	8.814	10.213	EPSD	COSMIC	7.780	Up-regulation
AGC_Akt_AKT1_ST	Q9BXL7	CARD11	P31749	AKT1	T871	T864A	864	Missense	distal	-7	no	8.814	8.614	EPSD	COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	Q9BXL7	CARD11	P31749	AKT1	T871	R869Q	869	Missense	proximal	-2	no	8.814	8.301	EPSD	COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	Q9BXL7	CARD11	P31749	AKT1	S923	P926S	926	Missense	distal	3	no	14.521	14.602	EPSD	COSMIC	7.780	Up-regulation
AGC_Akt_AKT1_ST	Q9BXL7	CARD11	P31749	AKT1	S923	S929R	929	Missense	distal	6	no	14.521	14.519	EPSD	COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	Q9BXL7	CARD11	P31749	AKT1	S923	R920C	920	Missense	distal	-3	no	14.521	8.347	EPSD	COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	Q9BXL7	CARD11	P31749	AKT1	S923	S925N	925	Missense	proximal	2	no	14.521	14.252	EPSD	COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	Q9BXL7	CARD11	P31749	AKT1	S923	R918Q	918	Missense	distal	-5	no	14.521	10.293	EPSD	COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	Q9BXL7	CARD11	P31749	AKT1	S925	P926S	926	Missense	proximal	1	no	7.654	7.810	EPSD	COSMIC	7.780	Gain
AGC_Akt_AKT1_ST	Q9BXL7	CARD11	P31749	AKT1	T1020	Q1018H	1018	Missense	proximal	-2	no	11.802	11.453	EPSD	COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	Q9BXL7	CARD11	P31749	AKT1	T1020	E1021K	1021	Missense	proximal	1	no	11.802	11.965	EPSD	COSMIC	7.780	Up-regulation
AGC_Akt_AKT1_ST	Q9BXL7	CARD11	P31749	AKT1	T1020	R1016K	1016	Missense	distal	-4	no	11.802	11.788	EPSD	COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	Q9BXL7	CARD11	P31749	AKT1	T1020	R1017K	1017	Missense	distal	-3	no	11.802	7.281	EPSD	COSMIC	7.780	Loss
AGC_Akt_AKT1_ST	Q9BXL7	CARD11	P31749	AKT1	T1020	I1024T	1024	Missense	distal	4	no	11.802	11.535	EPSD	COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	Q9BXL7	CARD11	P31749	AKT1	T1020	L1015F	1015	Missense	distal	-5	no	11.802	12.406	EPSD	COSMIC	7.780	Up-regulation
AGC_Akt_AKT1_ST	Q9BXL7	CARD11	P31749	AKT1	T1020	E1013K	1013	Missense	distal	-7	no	11.802	11.994	EPSD	COSMIC	7.780	Up-regulation
AGC_Akt_AKT1_ST	P19544	WT1	P31749	AKT1	S273	S268R	268	Missense	distal	-5	no	3.769	8.239	EPSD	COSMIC	7.780	Gain
AGC_Akt_AKT1_ST	P19544	WT1	P31749	AKT1	S365	R363S	363	Missense	proximal	-2	no	11.843	12.032	EPSD	COSMIC	7.780	Up-regulation
AGC_Akt_AKT1_ST	P19544	WT1	P31749	AKT1	S365	R372H	372	Missense	distal	7	no	11.843	11.771	EPSD	COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	P19544	WT1	P31749	AKT1	S365	R363Q	363	Missense	proximal	-2	no	11.843	11.330	EPSD	COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	P19544	WT1	P31749	AKT1	S365	R372C	372	Missense	distal	7	no	11.843	11.713	EPSD	COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	P19544	WT1	P31749	AKT1	S365	R363G	363	Missense	proximal	-2	no	11.843	11.337	EPSD	COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	P19544	WT1	P31749	AKT1	S365	R363L	363	Missense	proximal	-2	no	11.843	11.175	EPSD	COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	P19544	WT1	P31749	AKT1	S365	R363W	363	Missense	proximal	-2	no	11.843	10.589	EPSD	COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	P19544	WT1	P31749	AKT1	S428	F425L	425	Missense	distal	-3	no	9.245	7.845	EPSD	COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	P98177	FOXO4	P31749	AKT1	S197	A190G	190	Missense	distal	-7	no	15.494	15.457	EPSD;PhosphoSitePlus	COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	P98177	FOXO4	P31749	AKT1	S197	R194L	194	Missense	distal	-3	no	15.494	8.500	EPSD;PhosphoSitePlus	COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	P98177	FOXO4	P31749	AKT1	S197	A196T	196	Missense	proximal	-1	no	15.494	15.521	EPSD;PhosphoSitePlus	COSMIC	7.780	Up-regulation
AGC_Akt_AKT1_ST	P98177	FOXO4	P31749	AKT1	S197	A196V	196	Missense	proximal	-1	no	15.494	15.480	EPSD;PhosphoSitePlus	COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	P98177	FOXO4	P31749	AKT1	S197	R193S	193	Missense	distal	-4	no	15.494	15.409	EPSD;PhosphoSitePlus	COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	P98177	FOXO4	P31749	AKT1	S197	D199N	199	Missense	proximal	2	no	15.494	15.824	EPSD;PhosphoSitePlus	COSMIC	7.780	Up-regulation
AGC_Akt_AKT1_ST	P98177	FOXO4	P31749	AKT1	S217	S217F	217	Missense	central	0	yes	9.924	0.000	EPSD	COSMIC	7.780	Loss
AGC_Akt_AKT1_ST	P98177	FOXO4	P31749	AKT1	S217	P222Q	222	Missense	distal	5	no	9.924	9.933	EPSD	COSMIC	7.780	Up-regulation
AGC_Akt_AKT1_ST	P98177	FOXO4	P31749	AKT1	S217	L219M	219	Missense	proximal	2	no	9.924	10.053	EPSD	COSMIC	7.780	Up-regulation
AGC_Akt_AKT1_ST	P98177	FOXO4	P31749	AKT1	S260	P258S	258	Missense	proximal	-2	no	11.154	11.978	EPSD	COSMIC	7.780	Up-regulation
AGC_Akt_AKT1_ST	P98177	FOXO4	P31749	AKT1	S260	R257H	257	Missense	distal	-3	no	11.154	6.455	EPSD	COSMIC;GDSC;CCLE	7.780	Loss
AGC_Akt_AKT1_ST	P98177	FOXO4	P31749	AKT1	S262	P258S	258	Missense	distal	-4	no	16.238	16.974	PhosphoSitePlus;EPSD	COSMIC	7.780	Up-regulation
AGC_Akt_AKT1_ST	P98177	FOXO4	P31749	AKT1	S262	T269N	269	Missense	distal	7	no	16.238	16.192	PhosphoSitePlus;EPSD	COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	P98177	FOXO4	P31749	AKT1	S262	R257H	257	Missense	distal	-5	no	16.238	13.143	PhosphoSitePlus;EPSD	COSMIC;GDSC;CCLE	7.780	Down-regulation
AGC_Akt_AKT1_ST	P10276	RARA	P31749	AKT1	S369	H372Y	372	Missense	distal	3	no	16.466	16.498	EPSD	COSMIC	7.780	Up-regulation
AGC_Akt_AKT1_ST	P10276	RARA	P31749	AKT1	S369	R370H	370	Missense	proximal	1	no	16.466	16.143	EPSD	COSMIC;GDSC	7.780	Down-regulation
AGC_Akt_AKT1_ST	P10276	RARA	P31749	AKT1	S369	V363M	363	Missense	distal	-6	no	16.466	16.479	EPSD	COSMIC;GDSC;CCLE	7.780	Up-regulation
AGC_Akt_AKT1_ST	P10276	RARA	P31749	AKT1	S369	P371R	371	Missense	proximal	2	no	16.466	16.630	EPSD	COSMIC	7.780	Up-regulation
AGC_Akt_AKT1_ST	P10276	RARA	P31749	AKT1	S369	R367K	367	Missense	proximal	-2	no	16.466	16.905	EPSD	COSMIC	7.780	Up-regulation
AGC_Akt_AKT1_ST	P10276	RARA	P31749	AKT1	S447	P450F	450	Missense	distal	3	no	9.176	9.159	EPSD	COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	P10276	RARA	P31749	AKT1	S447	G442C	442	Missense	distal	-5	no	9.176	9.164	EPSD	COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	P10276	RARA	P31749	AKT1	S447	R454K	454	Missense	distal	7	no	9.176	9.169	EPSD	COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	P10276	RARA	P31749	AKT1	S447	S452F	452	Missense	distal	5	no	9.176	9.104	EPSD	COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	P10276	RARA	P31749	AKT1	S447	S447F	447	Missense	central	0	yes	9.176	0.000	EPSD	COSMIC	7.780	Loss
AGC_Akt_AKT1_ST	P10276	RARA	P31749	AKT1	S447	S451R	451	Missense	distal	4	no	9.176	9.187	EPSD	COSMIC	7.780	Up-regulation
AGC_Akt_AKT1_ST	P10276	RARA	P31749	AKT1	S449	P450F	450	Missense	proximal	1	no	9.466	9.639	EPSD	COSMIC	7.780	Up-regulation
AGC_Akt_AKT1_ST	P10276	RARA	P31749	AKT1	S449	G442C	442	Missense	distal	-7	no	9.466	9.230	EPSD	COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	P10276	RARA	P31749	AKT1	S449	R454K	454	Missense	distal	5	no	9.466	9.460	EPSD	COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	P10276	RARA	P31749	AKT1	S449	S452F	452	Missense	distal	3	no	9.466	9.368	EPSD	COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	P10276	RARA	P31749	AKT1	S449	S456R	456	Missense	distal	7	no	9.466	9.474	EPSD	COSMIC;CCLE	7.780	Up-regulation
AGC_Akt_AKT1_ST	P10276	RARA	P31749	AKT1	S449	S447F	447	Missense	proximal	-2	no	9.466	8.600	EPSD	COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	P10276	RARA	P31749	AKT1	S449	S451R	451	Missense	proximal	2	no	9.466	9.295	EPSD	COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	P10276	RARA	P31749	AKT1	S449	S456C	456	Missense	distal	7	no	9.466	9.344	EPSD	COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	P10276	RARA	P31749	AKT1	S451	P450F	450	Missense	proximal	-1	no	9.348	9.342	EPSD	COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	P10276	RARA	P31749	AKT1	S451	R454K	454	Missense	distal	3	no	9.348	9.367	EPSD	COSMIC	7.780	Up-regulation
AGC_Akt_AKT1_ST	P10276	RARA	P31749	AKT1	S451	P457L	457	Missense	distal	6	no	9.348	9.338	EPSD	COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	P10276	RARA	P31749	AKT1	S451	S452F	452	Missense	proximal	1	no	9.348	9.366	EPSD	COSMIC	7.780	Up-regulation
AGC_Akt_AKT1_ST	P10276	RARA	P31749	AKT1	S451	A458S	458	Missense	distal	7	no	9.348	9.399	EPSD	COSMIC;CCLE	7.780	Up-regulation
AGC_Akt_AKT1_ST	P10276	RARA	P31749	AKT1	S451	S456R	456	Missense	distal	5	no	9.348	9.355	EPSD	COSMIC;CCLE	7.780	Up-regulation
AGC_Akt_AKT1_ST	P10276	RARA	P31749	AKT1	S451	S447F	447	Missense	distal	-4	no	9.348	8.180	EPSD	COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	P10276	RARA	P31749	AKT1	S451	S451R	451	Missense	central	0	yes	9.348	0.000	EPSD	COSMIC	7.780	Loss
AGC_Akt_AKT1_ST	P10276	RARA	P31749	AKT1	S451	P457S	457	Missense	distal	6	no	9.348	9.441	EPSD	COSMIC	7.780	Up-regulation
AGC_Akt_AKT1_ST	P10276	RARA	P31749	AKT1	S451	S456C	456	Missense	distal	5	no	9.348	9.229	EPSD	COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	P10276	RARA	P31749	AKT1	S455	S452F	452	Missense	distal	-3	no	5.992	8.174	EPSD	COSMIC	7.780	Gain
AGC_Akt_AKT1_ST	P10276	RARA	P31749	AKT1	S456	S451R	451	Missense	distal	-5	no	7.264	11.735	EPSD	COSMIC	7.780	Gain
AGC_Akt_AKT1_ST	P10276	RARA	P31749	AKT1	T459	S461C	461	Missense	proximal	2	no	9.676	8.852	EPSD	COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	P10276	RARA	P31749	AKT1	T459	R454K	454	Missense	distal	-5	no	9.676	7.279	EPSD	COSMIC	7.780	Loss
AGC_Akt_AKT1_ST	P10276	RARA	P31749	AKT1	T459	P457L	457	Missense	proximal	-2	no	9.676	9.644	EPSD	COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	P10276	RARA	P31749	AKT1	T459	S452F	452	Missense	distal	-7	no	9.676	9.399	EPSD	COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	P10276	RARA	P31749	AKT1	T459	A458S	458	Missense	proximal	-1	no	9.676	9.697	EPSD	COSMIC;CCLE	7.780	Up-regulation
AGC_Akt_AKT1_ST	P10276	RARA	P31749	AKT1	T459	S456R	456	Missense	distal	-3	no	9.676	17.453	EPSD	COSMIC;CCLE	7.780	Up-regulation
AGC_Akt_AKT1_ST	P10276	RARA	P31749	AKT1	T459	P457S	457	Missense	proximal	-2	no	9.676	10.501	EPSD	COSMIC	7.780	Up-regulation
AGC_Akt_AKT1_ST	P10276	RARA	P31749	AKT1	T459	S456C	456	Missense	distal	-3	no	9.676	11.279	EPSD	COSMIC	7.780	Up-regulation
AGC_Akt_AKT1_ST	P10276	RARA	P31749	AKT1	S461	S456R	456	Missense	distal	-5	no	5.951	10.421	EPSD	COSMIC;CCLE	7.780	Gain
AGC_Akt_AKT1_ST	Q96S44	TP53RK	P31749	AKT1	T8	G12S	12	Missense	distal	4	no	12.189	12.016	EPSD	COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	P08727	KRT19	P31749	AKT1	S9	Y4F	4	Missense	distal	-5	no	7.162	8.249	EPSD	COSMIC;CCLE	7.780	Gain
AGC_Akt_AKT1_ST	P08727	KRT19	P31749	AKT1	S10	Y4F	4	Missense	distal	-6	no	13.670	13.654	EPSD	COSMIC;CCLE	7.780	Down-regulation
AGC_Akt_AKT1_ST	P08727	KRT19	P31749	AKT1	S10	G17V	17	Missense	distal	7	no	13.670	13.688	EPSD	COSMIC	7.780	Up-regulation
AGC_Akt_AKT1_ST	P08727	KRT19	P31749	AKT1	T12	G17V	17	Missense	distal	5	no	10.134	10.138	EPSD	COSMIC	7.780	Up-regulation
AGC_Akt_AKT1_ST	P08727	KRT19	P31749	AKT1	S14	G17V	17	Missense	distal	3	no	8.082	8.083	EPSD	COSMIC	7.780	Up-regulation
AGC_Akt_AKT1_ST	P08727	KRT19	P31749	AKT1	S93	L95P	95	Missense	proximal	2	no	9.315	9.524	EPSD	COSMIC	7.780	Up-regulation
AGC_Akt_AKT1_ST	P08727	KRT19	P31749	AKT1	S93	R90P	90	Missense	distal	-3	no	9.315	2.675	EPSD	COSMIC	7.780	Loss
AGC_Akt_AKT1_ST	P08727	KRT19	P31749	AKT1	S128	S124P	124	Missense	distal	-4	no	10.090	9.353	EPSD	COSMIC;GDSC	7.780	Down-regulation
AGC_Akt_AKT1_ST	P08727	KRT19	P31749	AKT1	T171	R176C	176	Missense	distal	5	no	9.225	9.099	EPSD	COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	P63104	YWHAZ	P31749	AKT1	S58	R55C	55	Missense	distal	-3	no	11.487	5.314	PhosphoSitePlus	COSMIC	7.780	Loss
AGC_Akt_AKT1_ST	P63104	YWHAZ	P31749	AKT1	T88	T88M	88	Missense	central	0	yes	9.570	0.000	EPSD	COSMIC	7.780	Loss
AGC_Akt_AKT1_ST	P63104	YWHAZ	P31749	AKT1	T88	E87V	87	Missense	proximal	-1	no	9.570	9.549	EPSD	COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	Q9Y3M2	CBY1	P31749	AKT1	S20	R16Q	16	Missense	distal	-4	no	10.579	9.958	PhosphoSitePlus	COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	Q9Y3M2	CBY1	P31749	AKT1	S22	R16Q	16	Missense	distal	-6	no	8.719	8.635	EPSD	COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	P98170	XIAP	P31749	AKT1	S9	G8R	8	Missense	proximal	-1	no	8.912	8.952	EPSD	COSMIC	7.780	Up-regulation
AGC_Akt_AKT1_ST	P98170	XIAP	P31749	AKT1	S9	A15T	15	Missense	distal	6	no	8.912	9.015	EPSD	COSMIC	7.780	Up-regulation
AGC_Akt_AKT1_ST	P98170	XIAP	P31749	AKT1	T32	E25Q	25	Missense	distal	-7	no	10.213	10.225	EPSD	COSMIC	7.780	Up-regulation
AGC_Akt_AKT1_ST	P98170	XIAP	P31749	AKT1	T32	G39D	39	Missense	distal	7	no	10.213	10.210	EPSD	COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	P98170	XIAP	P31749	AKT1	T32	E25K	25	Missense	distal	-7	no	10.213	10.406	EPSD	COSMIC	7.780	Up-regulation
AGC_Akt_AKT1_ST	P98170	XIAP	P31749	AKT1	S87	R91I	91	Missense	distal	4	no	15.077	15.328	PhosphoSitePlus	COSMIC	7.780	Up-regulation
AGC_Akt_AKT1_ST	P98170	XIAP	P31749	AKT1	S87	P88Q	88	Missense	proximal	1	no	15.077	15.082	PhosphoSitePlus	COSMIC	7.780	Up-regulation
AGC_Akt_AKT1_ST	P98170	XIAP	P31749	AKT1	S218	H223Q	223	Missense	distal	5	no	9.119	9.142	EPSD	COSMIC	7.780	Up-regulation
AGC_Akt_AKT1_ST	P98170	XIAP	P31749	AKT1	S261	L256V	256	Missense	distal	-5	no	12.601	12.413	EPSD	COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	P98170	XIAP	P31749	AKT1	S261	N259S	259	Missense	proximal	-2	no	12.601	13.287	EPSD	COSMIC	7.780	Up-regulation
AGC_Akt_AKT1_ST	P98170	XIAP	P31749	AKT1	T359	R365G	365	Missense	distal	6	no	8.121	8.017	EPSD	COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	P98170	XIAP	P31749	AKT1	T359	V353A	353	Missense	distal	-6	no	8.121	8.142	EPSD	COSMIC	7.780	Up-regulation
AGC_Akt_AKT1_ST	P98170	XIAP	P31749	AKT1	S361	R365G	365	Missense	distal	4	no	8.845	9.008	EPSD	COSMIC	7.780	Up-regulation
AGC_Akt_AKT1_ST	P98170	XIAP	P31749	AKT1	S361	D367Y	367	Missense	distal	6	no	8.845	8.906	EPSD	COSMIC	7.780	Up-regulation
AGC_Akt_AKT1_ST	P98170	XIAP	P31749	AKT1	T363	R365G	365	Missense	proximal	2	no	8.331	8.171	EPSD	COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	P98170	XIAP	P31749	AKT1	T363	D367Y	367	Missense	distal	4	no	8.331	8.242	EPSD	COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	P98170	XIAP	P31749	AKT1	S436	T437I	437	Missense	proximal	1	no	9.045	8.603	EPSD	COSMIC;GDSC;CCLE	7.780	Down-regulation
AGC_Akt_AKT1_ST	P98170	XIAP	P31749	AKT1	S436	Q432H	432	Missense	distal	-4	no	9.045	8.607	EPSD	COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	P98170	XIAP	P31749	AKT1	S436	S430L	430	Missense	distal	-6	no	9.045	8.995	EPSD	COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	Q92879	CELF1	P31749	AKT1	S28	L32M	32	Missense	distal	4	no	12.783	12.758	PhosphoSitePlus	COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	Q92879	CELF1	P31749	AKT1	S28	R33Q	33	Missense	distal	5	no	12.783	12.732	PhosphoSitePlus	COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	Q92879	CELF1	P31749	AKT1	S28	P24L	24	Missense	distal	-4	no	12.783	12.395	PhosphoSitePlus	COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	Q92879	CELF1	P31749	AKT1	S28	R33W	33	Missense	distal	5	no	12.783	12.688	PhosphoSitePlus	COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	Q92879	CELF1	P31749	AKT1	S52	Q53K	53	Missense	proximal	1	no	8.547	8.764	EPSD	COSMIC	7.780	Up-regulation
AGC_Akt_AKT1_ST	Q92879	CELF1	P31749	AKT1	S52	D50E	50	Missense	proximal	-2	no	8.547	9.531	EPSD	COSMIC	7.780	Up-regulation
AGC_Akt_AKT1_ST	Q92879	CELF1	P31749	AKT1	S52	R49T	49	Missense	distal	-3	no	8.547	1.525	EPSD	COSMIC	7.780	Loss
AGC_Akt_AKT1_ST	Q92879	CELF1	P31749	AKT1	S302	S299R	299	Missense	distal	-3	no	3.244	11.021	EPSD	COSMIC	7.780	Gain
AGC_Akt_AKT1_ST	Q92879	CELF1	P31749	AKT1	S304	S299R	299	Missense	distal	-5	no	5.219	9.689	EPSD	COSMIC	7.780	Gain
AGC_Akt_AKT1_ST	Q92879	CELF1	P31749	AKT1	S305	S302R	302	Missense	distal	-3	no	4.019	11.796	EPSD	COSMIC	7.780	Gain
AGC_Akt_AKT1_ST	P08047	SP1	P31749	AKT1	S73	E72K	72	Missense	proximal	-1	no	11.657	11.678	EPSD	COSMIC	7.780	Up-regulation
AGC_Akt_AKT1_ST	P08047	SP1	P31749	AKT1	S73	N79K	79	Missense	distal	6	no	11.657	11.735	EPSD	COSMIC	7.780	Up-regulation
AGC_Akt_AKT1_ST	P08047	SP1	P31749	AKT1	T651	R654M	654	Missense	distal	3	no	10.632	10.563	EPSD	COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	P08047	SP1	P31749	AKT1	T651	R644W	644	Missense	distal	-7	no	10.632	10.209	EPSD	COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	P08047	SP1	P31749	AKT1	T651	R654G	654	Missense	distal	3	no	10.632	10.558	EPSD	COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	P08047	SP1	P31749	AKT1	T651	R648C	648	Missense	distal	-3	no	10.632	4.458	EPSD	COSMIC	7.780	Loss
AGC_Akt_AKT1_ST	P08047	SP1	P31749	AKT1	T651	R648H	648	Missense	distal	-3	no	10.632	5.933	EPSD	COSMIC	7.780	Loss
AGC_Akt_AKT1_ST	P08047	SP1	P31749	AKT1	S670	Q674H	674	Missense	distal	4	no	9.797	9.859	EPSD	COSMIC	7.780	Up-regulation
AGC_Akt_AKT1_ST	P08047	SP1	P31749	AKT1	T679	Q674H	674	Missense	distal	-5	no	7.623	8.756	EPSD;PhosphoSitePlus	COSMIC	7.780	Gain
AGC_Akt_AKT1_ST	P08047	SP1	P31749	AKT1	T681	Q674H	674	Missense	distal	-7	no	11.855	11.748	EPSD	COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	P08047	SP1	P31749	AKT1	T681	R678H	678	Missense	distal	-3	no	11.855	7.157	EPSD	COSMIC	7.780	Loss
AGC_Akt_AKT1_ST	P08047	SP1	P31749	AKT1	S698	H700Y	700	Missense	proximal	2	no	7.812	7.973	PhosphoSitePlus;EPSD	COSMIC	7.780	Up-regulation
AGC_Akt_AKT1_ST	P08047	SP1	P31749	AKT1	S702	H700Y	700	Missense	proximal	-2	no	9.716	9.843	EPSD	COSMIC	7.780	Up-regulation
AGC_Akt_AKT1_ST	P49841	GSK3B	P31749	AKT1	T7	S9F	9	Missense	proximal	2	no	11.492	10.914	EPSD	COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	P49841	GSK3B	P31749	AKT1	T7	S2P	2	Missense	distal	-5	no	11.492	11.952	EPSD	COSMIC	7.780	Up-regulation
AGC_Akt_AKT1_ST	P49841	GSK3B	P31749	AKT1	S9	S9F	9	Missense	central	0	yes	17.010	0.000	PhosphoSitePlus	COSMIC	7.780	Loss
AGC_Akt_AKT1_ST	P49841	GSK3B	P31749	AKT1	S9	P16A	16	Missense	distal	7	no	17.010	17.017	PhosphoSitePlus	COSMIC	7.780	Up-regulation
AGC_Akt_AKT1_ST	P49841	GSK3B	P31749	AKT1	S9	S2P	2	Missense	distal	-7	no	17.010	16.816	PhosphoSitePlus	COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	P49841	GSK3B	P31749	AKT1	S13	S9F	9	Missense	distal	-4	no	7.992	6.825	EPSD	COSMIC	7.780	Loss
AGC_Akt_AKT1_ST	P49841	GSK3B	P31749	AKT1	S13	P16A	16	Missense	distal	3	no	7.992	8.016	EPSD	COSMIC	7.780	Up-regulation
AGC_Akt_AKT1_ST	P49841	GSK3B	P31749	AKT1	S35	D31Y	31	Missense	distal	-4	no	10.668	11.096	EPSD	COSMIC	7.780	Up-regulation
AGC_Akt_AKT1_ST	P49841	GSK3B	P31749	AKT1	S35	D33N	33	Missense	proximal	-2	no	10.668	11.376	EPSD	COSMIC	7.780	Up-regulation
AGC_Akt_AKT1_ST	P49841	GSK3B	P31749	AKT1	S35	S35R	35	Missense	central	0	yes	10.668	0.000	EPSD	COSMIC	7.780	Loss
AGC_Akt_AKT1_ST	P49841	GSK3B	P31749	AKT1	S35	V41G	41	Missense	distal	6	no	10.668	10.677	EPSD	COSMIC	7.780	Up-regulation
AGC_Akt_AKT1_ST	P49841	GSK3B	P31749	AKT1	S35	V37G	37	Missense	proximal	2	no	10.668	10.874	EPSD	COSMIC	7.780	Up-regulation
AGC_Akt_AKT1_ST	P49841	GSK3B	P31749	AKT1	S35	D33G	33	Missense	proximal	-2	no	10.668	11.367	EPSD	COSMIC;GDSC;CCLE	7.780	Up-regulation
AGC_Akt_AKT1_ST	P49841	GSK3B	P31749	AKT1	S35	D33H	33	Missense	proximal	-2	no	10.668	11.012	EPSD	COSMIC	7.780	Up-regulation
AGC_Akt_AKT1_ST	P49841	GSK3B	P31749	AKT1	S147	P154S	154	Missense	distal	7	no	10.133	10.191	EPSD	COSMIC	7.780	Up-regulation
AGC_Akt_AKT1_ST	P49841	GSK3B	P31749	AKT1	S147	Y146C	146	Missense	proximal	-1	no	10.133	10.099	EPSD	COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	P49841	GSK3B	P31749	AKT1	S147	R148Q	148	Missense	proximal	1	no	10.133	9.838	EPSD	COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	P49841	GSK3B	P31749	AKT1	S147	S147N	147	Missense	central	0	yes	10.133	0.000	EPSD	COSMIC	7.780	Loss
AGC_Akt_AKT1_ST	P49841	GSK3B	P31749	AKT1	S147	Y140C	140	Missense	distal	-7	no	10.133	9.916	EPSD	COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	P49841	GSK3B	P31749	AKT1	S147	A143G	143	Missense	distal	-4	no	10.133	10.126	EPSD	COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	P49841	GSK3B	P31749	AKT1	S147	R141S	141	Missense	distal	-6	no	10.133	10.099	EPSD	COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	P49841	GSK3B	P31749	AKT1	T408	R405S	405	Missense	distal	-3	no	12.001	4.225	EPSD	COSMIC	7.780	Loss
AGC_Akt_AKT1_ST	P49841	GSK3B	P31749	AKT1	T408	T402I	402	Missense	distal	-6	no	12.001	11.850	EPSD	COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	P49841	GSK3B	P31749	AKT1	T408	R405H	405	Missense	distal	-3	no	12.001	7.302	EPSD	COSMIC;CCLE	7.780	Loss
AGC_Akt_AKT1_ST	P23396	RPS3	P31749	AKT1	T70	V72E	72	Missense	proximal	2	no	14.505	14.854	PhosphoSitePlus	COSMIC	7.780	Up-regulation
AGC_Akt_AKT1_ST	P23396	RPS3	P31749	AKT1	T70	Q74R	74	Missense	distal	4	no	14.505	14.382	PhosphoSitePlus	COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	P23396	RPS3	P31749	AKT1	T70	R76M	76	Missense	distal	6	no	14.505	14.408	PhosphoSitePlus	COSMIC;CCLE	7.780	Down-regulation
AGC_Akt_AKT1_ST	P23396	RPS3	P31749	AKT1	S149	K148N	148	Missense	proximal	-1	no	11.883	11.859	EPSD	COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	P23396	RPS3	P31749	AKT1	S149	V153L	153	Missense	distal	4	no	11.883	11.892	EPSD	COSMIC	7.780	Up-regulation
AGC_Akt_AKT1_ST	P23396	RPS3	P31749	AKT1	S149	K151N	151	Missense	proximal	2	no	11.883	11.598	EPSD	COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	Q53EL6	PDCD4	P31749	AKT1	S76	G81E	81	Missense	distal	5	no	11.265	11.296	EPSD	COSMIC	7.780	Up-regulation
AGC_Akt_AKT1_ST	Q53EL6	PDCD4	P31749	AKT1	S78	G81E	81	Missense	distal	3	no	8.800	8.850	EPSD	COSMIC	7.780	Up-regulation
AGC_Akt_AKT1_ST	Q53EL6	PDCD4	P31749	AKT1	S78	A84V	84	Missense	distal	6	no	8.800	8.768	EPSD	COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	Q53EL6	PDCD4	P31749	AKT1	S224	G228W	228	Missense	distal	4	no	7.759	7.844	EPSD	COSMIC	7.780	Gain
AGC_Akt_AKT1_ST	Q53EL6	PDCD4	P31749	AKT1	S313	G307V	307	Missense	distal	-6	no	13.372	13.376	EPSD	COSMIC	7.780	Up-regulation
AGC_Akt_AKT1_ST	Q53EL6	PDCD4	P31749	AKT1	S457	G451D	451	Missense	distal	-6	no	19.966	19.927	EPSD;PhosphoSitePlus	COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	P61247	RPS3A	P31749	AKT1	T10	V3I	3	Missense	distal	-7	no	10.266	10.171	EPSD;PhosphoSitePlus	COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	P61247	RPS3A	P31749	AKT1	S154	N147K	147	Missense	distal	-7	no	11.269	11.426	EPSD	COSMIC	7.780	Up-regulation
AGC_Akt_AKT1_ST	P61247	RPS3A	P31749	AKT1	S154	Q157P	157	Missense	distal	3	no	11.269	11.261	EPSD	COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	P61247	RPS3A	P31749	AKT1	S154	R151Q	151	Missense	distal	-3	no	11.269	4.058	EPSD	COSMIC	7.780	Loss
AGC_Akt_AKT1_ST	P61247	RPS3A	P31749	AKT1	T242	S237R	237	Missense	distal	-5	no	5.839	10.309	EPSD	COSMIC	7.780	Gain
AGC_Akt_AKT1_ST	Q9H6Z4	RANBP3	P31749	AKT1	T75	S72R	72	Missense	distal	-3	no	2.236	10.012	EPSD	COSMIC	7.780	Gain
AGC_Akt_AKT1_ST	Q9H6Z4	RANBP3	P31749	AKT1	S100	S100F	100	Missense	central	0	yes	10.647	0.000	EPSD	COSMIC	7.780	Loss
AGC_Akt_AKT1_ST	Q9H6Z4	RANBP3	P31749	AKT1	S100	A93V	93	Missense	distal	-7	no	10.647	10.519	EPSD	COSMIC;CCLE	7.780	Down-regulation
AGC_Akt_AKT1_ST	Q9H6Z4	RANBP3	P31749	AKT1	T124	K120R	120	Missense	distal	-4	no	10.503	10.516	EPSD	COSMIC	7.780	Up-regulation
AGC_Akt_AKT1_ST	Q9H6Z4	RANBP3	P31749	AKT1	S125	K120R	120	Missense	distal	-5	no	8.185	10.583	EPSD	COSMIC	7.780	Up-regulation
AGC_Akt_AKT1_ST	Q9H6Z4	RANBP3	P31749	AKT1	S126	K120R	120	Missense	distal	-6	no	17.477	17.492	PhosphoSitePlus	COSMIC	7.780	Up-regulation
AGC_Akt_AKT1_ST	Q9H6Z4	RANBP3	P31749	AKT1	S186	P182S	182	Missense	distal	-4	no	7.378	8.114	EPSD	COSMIC	7.780	Gain
AGC_Akt_AKT1_ST	Q9H6Z4	RANBP3	P31749	AKT1	S221	D225N	225	Missense	distal	4	no	11.061	10.946	EPSD	COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	Q9H6Z4	RANBP3	P31749	AKT1	S333	M327I	327	Missense	distal	-6	no	11.137	11.079	EPSD	COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	Q9H6Z4	RANBP3	P31749	AKT1	S333	L332W	332	Missense	proximal	-1	no	11.137	11.116	EPSD	COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	Q9H6Z4	RANBP3	P31749	AKT1	S333	P334T	334	Missense	proximal	1	no	11.137	11.486	EPSD	COSMIC	7.780	Up-regulation
AGC_Akt_AKT1_ST	P49918	CDKN1C	P31749	AKT1	S306	G303V	303	Missense	distal	-3	no	7.937	7.828	EPSD	COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	Q9BVI0	PHF20	P31749	AKT1	S157	S158A	158	Missense	proximal	1	no	8.595	8.522	EPSD	COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	Q9BVI0	PHF20	P31749	AKT1	S265	R258S	258	Missense	distal	-7	no	15.666	15.610	PhosphoSitePlus;EPSD	COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	Q9BVI0	PHF20	P31749	AKT1	S265	P268S	268	Missense	distal	3	no	15.666	15.747	PhosphoSitePlus;EPSD	COSMIC	7.780	Up-regulation
AGC_Akt_AKT1_ST	Q9BVI0	PHF20	P31749	AKT1	S291	G293R	293	Missense	proximal	2	no	15.793	15.953	EPSD;PhosphoSitePlus	COSMIC	7.780	Up-regulation
AGC_Akt_AKT1_ST	Q9BVI0	PHF20	P31749	AKT1	S291	G293V	293	Missense	proximal	2	no	15.793	15.587	EPSD;PhosphoSitePlus	COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	Q9BVI0	PHF20	P31749	AKT1	S291	R287T	287	Missense	distal	-4	no	15.793	15.763	EPSD;PhosphoSitePlus	COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	Q9BVI0	PHF20	P31749	AKT1	S328	N334D	334	Missense	distal	6	no	12.591	12.509	EPSD	COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	Q9BVI0	PHF20	P31749	AKT1	S329	N334D	334	Missense	distal	5	no	10.877	10.837	EPSD	COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	Q9BVI0	PHF20	P31749	AKT1	S332	N334D	334	Missense	proximal	2	no	9.521	9.191	EPSD	COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	Q9BVI0	PHF20	P31749	AKT1	T333	N334D	334	Missense	proximal	1	no	10.213	10.088	EPSD	COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	Q9BVI0	PHF20	P31749	AKT1	S500	P499T	499	Missense	proximal	-1	no	10.263	10.298	EPSD	COSMIC	7.780	Up-regulation
AGC_Akt_AKT1_ST	Q9BVI0	PHF20	P31749	AKT1	S500	P505L	505	Missense	distal	5	no	10.263	10.249	EPSD	COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	Q9BVI0	PHF20	P31749	AKT1	S502	P499T	499	Missense	distal	-3	no	8.563	8.182	EPSD	COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	Q9BVI0	PHF20	P31749	AKT1	S502	P505L	505	Missense	distal	3	no	8.563	8.547	EPSD	COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	P35226	BMI1	P31749	AKT1	S315	N310K	310	Missense	distal	-5	no	8.854	10.941	EPSD	COSMIC	7.780	Up-regulation
AGC_Akt_AKT1_ST	P35226	BMI1	P31749	AKT1	S315	S315L	315	Missense	central	0	yes	8.854	0.000	EPSD	COSMIC	7.780	Loss
AGC_Akt_AKT1_ST	P35226	BMI1	P31749	AKT1	S315	P312H	312	Missense	distal	-3	no	8.854	10.795	EPSD	COSMIC	7.780	Up-regulation
AGC_Akt_AKT1_ST	P35226	BMI1	P31749	AKT1	S316	N310K	310	Missense	distal	-6	no	19.382	19.449	PhosphoSitePlus	COSMIC	7.780	Up-regulation
AGC_Akt_AKT1_ST	P35226	BMI1	P31749	AKT1	S316	S315L	315	Missense	proximal	-1	no	19.382	19.354	PhosphoSitePlus	COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	P35226	BMI1	P31749	AKT1	S316	P312H	312	Missense	distal	-4	no	19.382	19.145	PhosphoSitePlus	COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	Q15910	EZH2	P31749	AKT1	S8	G5W	5	Missense	distal	-3	no	8.046	5.862	EPSD	COSMIC	7.780	Loss
AGC_Akt_AKT1_ST	Q15910	EZH2	P31749	AKT1	S8	G2C	2	Missense	distal	-6	no	8.046	7.979	EPSD	COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	Q15910	EZH2	P31749	AKT1	S8	S8F	8	Missense	central	0	yes	8.046	0.000	EPSD	COSMIC	7.780	Loss
AGC_Akt_AKT1_ST	Q15910	EZH2	P31749	AKT1	S8	G2S	2	Missense	distal	-6	no	8.046	8.125	EPSD	COSMIC	7.780	Up-regulation
AGC_Akt_AKT1_ST	Q15910	EZH2	P31749	AKT1	S8	V13A	13	Missense	distal	5	no	8.046	8.055	EPSD	COSMIC	7.780	Up-regulation
AGC_Akt_AKT1_ST	Q15910	EZH2	P31749	AKT1	S8	Q3L	3	Missense	distal	-5	no	8.046	8.147	EPSD	COSMIC	7.780	Up-regulation
AGC_Akt_AKT1_ST	Q15910	EZH2	P31749	AKT1	S8	G5R	5	Missense	distal	-3	no	8.046	14.802	EPSD	COSMIC	7.780	Up-regulation
AGC_Akt_AKT1_ST	Q15910	EZH2	P31749	AKT1	S21	R16Q	16	Missense	distal	-5	no	15.763	11.535	PhosphoSitePlus	COSMIC;GDSC;CCLE	7.780	Down-regulation
AGC_Akt_AKT1_ST	Q15910	EZH2	P31749	AKT1	S21	Q28R	28	Missense	distal	7	no	15.763	15.819	PhosphoSitePlus	COSMIC	7.780	Up-regulation
AGC_Akt_AKT1_ST	Q15910	EZH2	P31749	AKT1	S21	L26P	26	Missense	distal	5	no	15.763	15.776	PhosphoSitePlus	COSMIC	7.780	Up-regulation
AGC_Akt_AKT1_ST	Q15910	EZH2	P31749	AKT1	S21	R18H	18	Missense	distal	-3	no	15.763	11.064	PhosphoSitePlus	COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	Q15910	EZH2	P31749	AKT1	S21	R16W	16	Missense	distal	-5	no	15.763	10.243	PhosphoSitePlus	COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	Q15910	EZH2	P31749	AKT1	S212	R207W	207	Missense	distal	-5	no	10.215	4.695	EPSD	COSMIC	7.780	Loss
AGC_Akt_AKT1_ST	Q15910	EZH2	P31749	AKT1	S212	R213H	213	Missense	proximal	1	no	10.215	9.893	EPSD	COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	Q15910	EZH2	P31749	AKT1	S212	R213C	213	Missense	proximal	1	no	10.215	9.687	EPSD	COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	Q15910	EZH2	P31749	AKT1	S212	K210E	210	Missense	proximal	-2	no	10.215	9.556	EPSD	COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	Q15910	EZH2	P31749	AKT1	S212	P219S	219	Missense	distal	7	no	10.215	10.274	EPSD	COSMIC;GDSC;CCLE	7.780	Up-regulation
AGC_Akt_AKT1_ST	Q15910	EZH2	P31749	AKT1	S212	P215S	215	Missense	distal	3	no	10.215	10.297	EPSD	COSMIC;GDSC	7.780	Up-regulation
AGC_Akt_AKT1_ST	Q15910	EZH2	P31749	AKT1	S212	R216W	216	Missense	distal	4	no	10.215	10.462	EPSD	COSMIC	7.780	Up-regulation
AGC_Akt_AKT1_ST	Q15910	EZH2	P31749	AKT1	S212	H206Q	206	Missense	distal	-6	no	10.215	10.250	EPSD	COSMIC	7.780	Up-regulation
AGC_Akt_AKT1_ST	Q15910	EZH2	P31749	AKT1	S277	S271C	271	Missense	distal	-6	no	12.745	12.599	EPSD	COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	Q15910	EZH2	P31749	AKT1	S277	H279Q	279	Missense	proximal	2	no	12.745	12.989	EPSD	COSMIC	7.780	Up-regulation
AGC_Akt_AKT1_ST	Q15910	EZH2	P31749	AKT1	S277	H282Y	282	Missense	distal	5	no	12.745	12.769	EPSD	COSMIC	7.780	Up-regulation
AGC_Akt_AKT1_ST	Q15910	EZH2	P31749	AKT1	S277	T283M	283	Missense	distal	6	no	12.745	12.626	EPSD	COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	Q15910	EZH2	P31749	AKT1	S277	H279Y	279	Missense	proximal	2	no	12.745	12.906	EPSD	COSMIC;GDSC;CCLE	7.780	Up-regulation
AGC_Akt_AKT1_ST	Q15910	EZH2	P31749	AKT1	S277	S280C	280	Missense	distal	3	no	12.745	12.568	EPSD	COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	Q15910	EZH2	P31749	AKT1	T302	H297R	297	Missense	distal	-5	no	5.409	8.504	EPSD	COSMIC	7.780	Gain
AGC_Akt_AKT1_ST	Q15910	EZH2	P31749	AKT1	T305	H300R	300	Missense	distal	-5	no	5.493	8.588	EPSD	COSMIC	7.780	Gain
AGC_Akt_AKT1_ST	Q15910	EZH2	P31749	AKT1	T311	R308Q	308	Missense	distal	-3	no	12.206	4.995	EPSD	COSMIC	7.780	Loss
AGC_Akt_AKT1_ST	Q15910	EZH2	P31749	AKT1	T311	N317S	317	Missense	distal	6	no	12.206	12.273	EPSD	COSMIC	7.780	Up-regulation
AGC_Akt_AKT1_ST	Q15910	EZH2	P31749	AKT1	T311	L315V	315	Missense	distal	4	no	12.206	12.197	EPSD	COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	Q15910	EZH2	P31749	AKT1	T311	N304S	304	Missense	distal	-7	no	12.206	12.320	EPSD	COSMIC	7.780	Up-regulation
AGC_Akt_AKT1_ST	Q15910	EZH2	P31749	AKT1	T311	R308L	308	Missense	distal	-3	no	12.206	5.212	EPSD	COSMIC	7.780	Loss
AGC_Akt_AKT1_ST	Q15910	EZH2	P31749	AKT1	T311	R308W	308	Missense	distal	-3	no	12.206	3.265	EPSD	COSMIC	7.780	Loss
AGC_Akt_AKT1_ST	Q15910	EZH2	P31749	AKT1	T311	L315P	315	Missense	distal	4	no	12.206	12.173	EPSD	COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	Q15910	EZH2	P31749	AKT1	T311	E312K	312	Missense	proximal	1	no	12.206	12.369	EPSD	COSMIC	7.780	Up-regulation
AGC_Akt_AKT1_ST	Q15910	EZH2	P31749	AKT1	T311	N310S	310	Missense	proximal	-1	no	12.206	12.224	EPSD	COSMIC	7.780	Up-regulation
AGC_Akt_AKT1_ST	Q15910	EZH2	P31749	AKT1	T345	R342W	342	Missense	distal	-3	no	10.433	1.493	EPSD	COSMIC	7.780	Loss
AGC_Akt_AKT1_ST	Q15910	EZH2	P31749	AKT1	T345	R349C	349	Missense	distal	4	no	10.433	10.767	EPSD	COSMIC	7.780	Up-regulation
AGC_Akt_AKT1_ST	Q15910	EZH2	P31749	AKT1	T345	R342Q	342	Missense	distal	-3	no	10.433	3.222	EPSD	COSMIC;CCLE	7.780	Loss
AGC_Akt_AKT1_ST	Q15910	EZH2	P31749	AKT1	T345	R342L	342	Missense	distal	-3	no	10.433	3.439	EPSD	COSMIC	7.780	Loss
AGC_Akt_AKT1_ST	Q15910	EZH2	P31749	AKT1	T345	A340T	340	Missense	distal	-5	no	10.433	10.558	EPSD	COSMIC;CCLE	7.780	Up-regulation
AGC_Akt_AKT1_ST	Q15910	EZH2	P31749	AKT1	T345	E341K	341	Missense	distal	-4	no	10.433	11.017	EPSD	COSMIC	7.780	Up-regulation
AGC_Akt_AKT1_ST	Q15910	EZH2	P31749	AKT1	T345	L338F	338	Missense	distal	-7	no	10.433	10.389	EPSD	COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	Q15910	EZH2	P31749	AKT1	S362	P359S	359	Missense	distal	-3	no	8.380	7.244	EPSD	COSMIC	7.780	Loss
AGC_Akt_AKT1_ST	Q15910	EZH2	P31749	AKT1	S362	S363N	363	Missense	proximal	1	no	8.380	8.292	EPSD	COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	Q15910	EZH2	P31749	AKT1	S362	P368S	368	Missense	distal	6	no	8.380	8.474	EPSD	COSMIC	7.780	Up-regulation
AGC_Akt_AKT1_ST	Q15910	EZH2	P31749	AKT1	S362	R357L	357	Missense	distal	-5	no	8.380	4.254	EPSD	COSMIC	7.780	Loss
AGC_Akt_AKT1_ST	Q15910	EZH2	P31749	AKT1	S362	S363C	363	Missense	proximal	1	no	8.380	7.997	EPSD	COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	Q15910	EZH2	P31749	AKT1	S362	R355G	355	Missense	distal	-7	no	8.380	8.138	EPSD	COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	Q15910	EZH2	P31749	AKT1	S362	N361T	361	Missense	proximal	-1	no	8.380	8.404	EPSD	COSMIC	7.780	Up-regulation
AGC_Akt_AKT1_ST	Q15910	EZH2	P31749	AKT1	S362	S366L	366	Missense	distal	4	no	8.380	8.569	EPSD	COSMIC	7.780	Up-regulation
AGC_Akt_AKT1_ST	Q15910	EZH2	P31749	AKT1	T367	S363N	363	Missense	distal	-4	no	10.054	9.487	EPSD	COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	Q15910	EZH2	P31749	AKT1	T367	P368S	368	Missense	proximal	1	no	10.054	10.209	EPSD	COSMIC	7.780	Up-regulation
AGC_Akt_AKT1_ST	Q15910	EZH2	P31749	AKT1	T367	E374Q	374	Missense	distal	7	no	10.054	10.039	EPSD	COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	Q15910	EZH2	P31749	AKT1	T367	L373V	373	Missense	distal	6	no	10.054	10.043	EPSD	COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	Q15910	EZH2	P31749	AKT1	T367	S363C	363	Missense	distal	-4	no	10.054	8.461	EPSD	COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	Q15910	EZH2	P31749	AKT1	T367	N361T	361	Missense	distal	-6	no	10.054	10.131	EPSD	COSMIC	7.780	Up-regulation
AGC_Akt_AKT1_ST	Q15910	EZH2	P31749	AKT1	T367	S366L	366	Missense	proximal	-1	no	10.054	10.025	EPSD	COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	Q15910	EZH2	P31749	AKT1	S406	R413W	413	Missense	distal	7	no	8.358	8.260	EPSD	COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	Q15910	EZH2	P31749	AKT1	S406	S405L	405	Missense	proximal	-1	no	8.358	8.329	EPSD	COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	Q15910	EZH2	P31749	AKT1	S406	E409K	409	Missense	distal	3	no	8.358	8.401	EPSD	COSMIC	7.780	Up-regulation
AGC_Akt_AKT1_ST	Q15910	EZH2	P31749	AKT1	S406	S408F	408	Missense	proximal	2	no	8.358	7.781	EPSD	COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	Q15910	EZH2	P31749	AKT1	S406	S412F	412	Missense	distal	6	no	8.358	8.238	EPSD	COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	Q15910	EZH2	P31749	AKT1	S406	R413Q	413	Missense	distal	7	no	8.358	8.302	EPSD	COSMIC;CCLE	7.780	Down-regulation
AGC_Akt_AKT1_ST	Q15910	EZH2	P31749	AKT1	T416	P422L	422	Missense	distal	6	no	8.747	8.737	EPSD	COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	Q15910	EZH2	P31749	AKT1	T416	P422Q	422	Missense	distal	6	no	8.747	8.768	EPSD	COSMIC	7.780	Up-regulation
AGC_Akt_AKT1_ST	Q15910	EZH2	P31749	AKT1	T416	R413W	413	Missense	distal	-3	no	8.747	-0.194	EPSD	COSMIC	7.780	Loss
AGC_Akt_AKT1_ST	Q15910	EZH2	P31749	AKT1	T416	P417L	417	Missense	proximal	1	no	8.747	9.000	EPSD	COSMIC	7.780	Up-regulation
AGC_Akt_AKT1_ST	Q15910	EZH2	P31749	AKT1	T416	E409K	409	Missense	distal	-7	no	8.747	8.939	EPSD	COSMIC	7.780	Up-regulation
AGC_Akt_AKT1_ST	Q15910	EZH2	P31749	AKT1	T416	S412F	412	Missense	distal	-4	no	8.747	7.579	EPSD	COSMIC	7.780	Loss
AGC_Akt_AKT1_ST	Q15910	EZH2	P31749	AKT1	T416	N423T	423	Missense	distal	7	no	8.747	8.792	EPSD	COSMIC	7.780	Up-regulation
AGC_Akt_AKT1_ST	Q15910	EZH2	P31749	AKT1	T416	Q415E	415	Missense	proximal	-1	no	8.747	8.754	EPSD	COSMIC	7.780	Up-regulation
AGC_Akt_AKT1_ST	Q15910	EZH2	P31749	AKT1	T416	P417Q	417	Missense	proximal	1	no	8.747	8.752	EPSD	COSMIC	7.780	Up-regulation
AGC_Akt_AKT1_ST	Q15910	EZH2	P31749	AKT1	T416	R413Q	413	Missense	distal	-3	no	8.747	1.535	EPSD	COSMIC;CCLE	7.780	Loss
AGC_Akt_AKT1_ST	Q15910	EZH2	P31749	AKT1	S475	P479A	479	Missense	distal	4	no	9.507	9.475	EPSD	COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	Q15910	EZH2	P31749	AKT1	S475	P479S	479	Missense	distal	4	no	9.507	9.351	EPSD	COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	Q15910	EZH2	P31749	AKT1	S475	A482T	482	Missense	distal	7	no	9.507	9.568	EPSD	COSMIC	7.780	Up-regulation
AGC_Akt_AKT1_ST	Q15910	EZH2	P31749	AKT1	S475	S474F	474	Missense	proximal	-1	no	9.507	9.472	EPSD	COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	Q15910	EZH2	P31749	AKT1	S475	P481S	481	Missense	distal	6	no	9.507	9.601	EPSD	COSMIC	7.780	Up-regulation
AGC_Akt_AKT1_ST	Q15910	EZH2	P31749	AKT1	S475	E473K	473	Missense	proximal	-2	no	9.507	10.166	EPSD	COSMIC	7.780	Up-regulation
AGC_Akt_AKT1_ST	Q15910	EZH2	P31749	AKT1	S475	S474Y	474	Missense	proximal	-1	no	9.507	9.481	EPSD	COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	Q15910	EZH2	P31749	AKT1	S514	N515T	515	Missense	proximal	1	no	7.504	7.786	EPSD	COSMIC	7.780	Gain
AGC_Akt_AKT1_ST	Q15910	EZH2	P31749	AKT1	S690	R685S	685	Missense	distal	-5	no	8.977	4.507	EPSD	COSMIC	7.780	Loss
AGC_Akt_AKT1_ST	Q15910	EZH2	P31749	AKT1	S690	R685C	685	Missense	distal	-5	no	8.977	4.900	EPSD	COSMIC	7.780	Loss
AGC_Akt_AKT1_ST	Q15910	EZH2	P31749	AKT1	S690	K683N	683	Missense	distal	-7	no	8.977	8.820	EPSD	COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	Q15910	EZH2	P31749	AKT1	S690	S690P	690	Missense	central	0	yes	8.977	0.000	EPSD	COSMIC	7.780	Loss
AGC_Akt_AKT1_ST	Q15910	EZH2	P31749	AKT1	S690	N688T	688	Missense	proximal	-2	no	8.977	9.596	EPSD	COSMIC	7.780	Up-regulation
AGC_Akt_AKT1_ST	Q15910	EZH2	P31749	AKT1	S690	H689Y	689	Missense	proximal	-1	no	8.977	8.985	EPSD	COSMIC	7.780	Up-regulation
AGC_Akt_AKT1_ST	Q15910	EZH2	P31749	AKT1	S690	H689R	689	Missense	proximal	-1	no	8.977	9.022	EPSD	COSMIC	7.780	Up-regulation
AGC_Akt_AKT1_ST	Q15910	EZH2	P31749	AKT1	S690	N692D	692	Missense	proximal	2	no	8.977	8.647	EPSD	COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	Q15910	EZH2	P31749	AKT1	S690	N688I	688	Missense	proximal	-2	no	8.977	8.422	EPSD	COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	Q15910	EZH2	P31749	AKT1	S690	S690I	690	Missense	central	0	yes	8.977	0.000	EPSD	COSMIC	7.780	Loss
AGC_Akt_AKT1_ST	Q15910	EZH2	P31749	AKT1	S729	Y726H	726	Missense	distal	-3	no	5.785	8.675	EPSD	COSMIC	7.780	Gain
AGC_Akt_AKT1_ST	Q96BF3	TMIGD2	P31749	AKT1	S220	K214T	214	Missense	distal	-6	no	12.161	12.171	PhosphoSitePlus	COSMIC	7.780	Up-regulation
AGC_Akt_AKT1_ST	Q96BF3	TMIGD2	P31749	AKT1	S220	F226S	226	Missense	distal	6	no	12.161	12.280	PhosphoSitePlus	COSMIC	7.780	Up-regulation
AGC_Akt_AKT1_ST	Q96BF3	TMIGD2	P31749	AKT1	S220	P227R	227	Missense	distal	7	no	12.161	12.226	PhosphoSitePlus	COSMIC	7.780	Up-regulation
AGC_Akt_AKT1_ST	Q96BF3	TMIGD2	P31749	AKT1	S220	G213E	213	Missense	distal	-7	no	12.161	12.197	PhosphoSitePlus	COSMIC	7.780	Up-regulation
AGC_Akt_AKT1_ST	Q96BF3	TMIGD2	P31749	AKT1	S220	P227L	227	Missense	distal	7	no	12.161	12.153	PhosphoSitePlus	COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	Q96BF3	TMIGD2	P31749	AKT1	T268	G275R	275	Missense	distal	7	no	8.266	8.346	EPSD	COSMIC	7.780	Up-regulation
AGC_Akt_AKT1_ST	Q96BF3	TMIGD2	P31749	AKT1	T268	S262F	262	Missense	distal	-6	no	8.266	8.191	EPSD	COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	P49760	CLK2	P31749	AKT1	S9	R15Q	15	Missense	distal	6	no	13.250	13.179	EPSD	COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	P49760	CLK2	P31749	AKT1	S9	Y7F	7	Missense	proximal	-2	no	13.250	13.305	EPSD	COSMIC	7.780	Up-regulation
AGC_Akt_AKT1_ST	P49760	CLK2	P31749	AKT1	S10	R15Q	15	Missense	distal	5	no	9.218	9.168	EPSD	COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	P49760	CLK2	P31749	AKT1	S10	Y7F	7	Missense	distal	-3	no	9.218	11.213	EPSD	COSMIC	7.780	Up-regulation
AGC_Akt_AKT1_ST	P49760	CLK2	P31749	AKT1	S17	R19C	19	Missense	proximal	2	no	8.588	7.935	EPSD	COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	P49760	CLK2	P31749	AKT1	S17	H21Y	21	Missense	distal	4	no	8.588	8.528	EPSD	COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	P49760	CLK2	P31749	AKT1	S17	R15Q	15	Missense	proximal	-2	no	8.588	8.075	EPSD	COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	P49760	CLK2	P31749	AKT1	S34	S36L	36	Missense	proximal	2	no	16.698	16.153	PhosphoSitePlus;EPSD	COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	P49760	CLK2	P31749	AKT1	S36	T42A	42	Missense	distal	6	no	17.235	17.132	EPSD	COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	P49760	CLK2	P31749	AKT1	S36	S36L	36	Missense	central	0	yes	17.235	0.000	EPSD	COSMIC	7.780	Loss
AGC_Akt_AKT1_ST	P49760	CLK2	P31749	AKT1	S50	R45H	45	Missense	distal	-5	no	15.690	12.595	EPSD	COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	P49760	CLK2	P31749	AKT1	S50	R45C	45	Missense	distal	-5	no	15.690	11.613	EPSD	COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	P49760	CLK2	P31749	AKT1	S57	D60N	60	Missense	distal	3	no	11.612	11.667	EPSD	COSMIC	7.780	Up-regulation
AGC_Akt_AKT1_ST	P49760	CLK2	P31749	AKT1	S106	R103Q	103	Missense	distal	-3	no	11.851	4.640	EPSD	COSMIC	7.780	Loss
AGC_Akt_AKT1_ST	P49760	CLK2	P31749	AKT1	T127	R120W	120	Missense	distal	-7	no	15.979	15.556	EPSD;PhosphoSitePlus	COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	P49760	CLK2	P31749	AKT1	T127	R123H	123	Missense	distal	-4	no	15.979	14.920	EPSD;PhosphoSitePlus	COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	P49760	CLK2	P31749	AKT1	T127	S132L	132	Missense	distal	5	no	15.979	15.912	EPSD;PhosphoSitePlus	COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	P49760	CLK2	P31749	AKT1	T127	R120Q	120	Missense	distal	-7	no	15.979	15.784	EPSD;PhosphoSitePlus	COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	P49760	CLK2	P31749	AKT1	T127	S131T	131	Missense	distal	4	no	15.979	15.974	EPSD;PhosphoSitePlus	COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	P49760	CLK2	P31749	AKT1	S133	S132L	132	Missense	proximal	-1	no	13.315	13.286	EPSD	COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	P49760	CLK2	P31749	AKT1	S133	S131T	131	Missense	proximal	-2	no	13.315	13.248	EPSD	COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	P49760	CLK2	P31749	AKT1	S133	R138W	138	Missense	distal	5	no	13.315	13.220	EPSD	COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	P49760	CLK2	P31749	AKT1	S133	S136N	136	Missense	distal	3	no	13.315	13.259	EPSD	COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	P49760	CLK2	P31749	AKT1	S133	R138Q	138	Missense	distal	5	no	13.315	13.264	EPSD	COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	P49760	CLK2	P31749	AKT1	S142	R138W	138	Missense	distal	-4	no	11.120	9.571	EPSD	COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	P49760	CLK2	P31749	AKT1	S142	S136N	136	Missense	distal	-6	no	11.120	11.074	EPSD	COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	P49760	CLK2	P31749	AKT1	S142	E144Q	144	Missense	proximal	2	no	11.120	11.020	EPSD	COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	P49760	CLK2	P31749	AKT1	S142	R138Q	138	Missense	distal	-4	no	11.120	10.499	EPSD	COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	P49760	CLK2	P31749	AKT1	S167	S167G	167	Missense	central	0	yes	8.416	0.000	EPSD	COSMIC	7.780	Loss
AGC_Akt_AKT1_ST	P49760	CLK2	P31749	AKT1	S167	G170V	170	Missense	distal	3	no	8.416	8.417	EPSD	COSMIC	7.780	Up-regulation
AGC_Akt_AKT1_ST	P49760	CLK2	P31749	AKT1	S167	Q160K	160	Missense	distal	-7	no	8.416	8.597	EPSD	COSMIC	7.780	Up-regulation
AGC_Akt_AKT1_ST	P10275	AR	P31749	AKT1	S16	A22T	22	Missense	distal	6	no	12.059	12.161	EPSD	COSMIC	7.780	Up-regulation
AGC_Akt_AKT1_ST	P10275	AR	P31749	AKT1	S16	F23L	23	Missense	distal	7	no	12.059	12.066	EPSD	COSMIC	7.780	Up-regulation
AGC_Akt_AKT1_ST	P10275	AR	P31749	AKT1	S16	R13W	13	Missense	distal	-3	no	12.059	3.118	EPSD	COSMIC	7.780	Loss
AGC_Akt_AKT1_ST	P10275	AR	P31749	AKT1	S16	G21A	21	Missense	distal	5	no	12.059	12.070	EPSD	COSMIC	7.780	Up-regulation
AGC_Akt_AKT1_ST	P10275	AR	P31749	AKT1	S16	P12A	12	Missense	distal	-4	no	12.059	12.073	EPSD	COSMIC	7.780	Up-regulation
AGC_Akt_AKT1_ST	P10275	AR	P31749	AKT1	T18	A22T	22	Missense	distal	4	no	9.744	9.614	EPSD	COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	P10275	AR	P31749	AKT1	T18	F23L	23	Missense	distal	5	no	9.744	9.750	EPSD	COSMIC	7.780	Up-regulation
AGC_Akt_AKT1_ST	P10275	AR	P31749	AKT1	T18	Q24H	24	Missense	distal	6	no	9.744	9.695	EPSD	COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	P10275	AR	P31749	AKT1	T18	R13W	13	Missense	distal	-5	no	9.744	4.224	EPSD	COSMIC	7.780	Loss
AGC_Akt_AKT1_ST	P10275	AR	P31749	AKT1	T18	G21A	21	Missense	distal	3	no	9.744	9.777	EPSD	COSMIC	7.780	Up-regulation
AGC_Akt_AKT1_ST	P10275	AR	P31749	AKT1	T18	P12A	12	Missense	distal	-6	no	9.744	9.753	EPSD	COSMIC	7.780	Up-regulation
AGC_Akt_AKT1_ST	P10275	AR	P31749	AKT1	S215	S220F	220	Missense	distal	5	no	14.508	14.435	EPSD;PhosphoSitePlus	COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	P10275	AR	P31749	AKT1	S215	S215L	215	Missense	central	0	yes	14.508	0.000	EPSD;PhosphoSitePlus	COSMIC	7.780	Loss
AGC_Akt_AKT1_ST	P10275	AR	P31749	AKT1	S215	A217V	217	Missense	proximal	2	no	14.508	14.346	EPSD;PhosphoSitePlus	COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	P10275	AR	P31749	AKT1	S215	A217D	217	Missense	proximal	2	no	14.508	14.285	EPSD;PhosphoSitePlus	COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	P10275	AR	P31749	AKT1	S215	A217T	217	Missense	proximal	2	no	14.508	14.809	EPSD;PhosphoSitePlus	COSMIC	7.780	Up-regulation
AGC_Akt_AKT1_ST	P10275	AR	P31749	AKT1	S215	A214V	214	Missense	proximal	-1	no	14.508	14.494	EPSD;PhosphoSitePlus	COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	P10275	AR	P31749	AKT1	S244	K241R	241	Missense	distal	-3	no	7.182	11.702	EPSD	COSMIC	7.780	Gain
AGC_Akt_AKT1_ST	P10275	AR	P31749	AKT1	S246	K241R	241	Missense	distal	-5	no	6.761	9.158	EPSD	COSMIC	7.780	Gain
AGC_Akt_AKT1_ST	P10275	AR	P31749	AKT1	S424	G421R	421	Missense	distal	-3	no	5.934	12.690	EPSD	COSMIC	7.780	Gain
AGC_Akt_AKT1_ST	P10275	AR	P31749	AKT1	S426	G421R	421	Missense	distal	-5	no	5.008	9.072	EPSD	COSMIC	7.780	Gain
AGC_Akt_AKT1_ST	P10275	AR	P31749	AKT1	S651	S648R	648	Missense	distal	-3	no	5.651	13.427	EPSD	COSMIC	7.780	Gain
AGC_Akt_AKT1_ST	P10275	AR	P31749	AKT1	T653	S648R	648	Missense	distal	-5	no	6.631	11.101	EPSD	COSMIC	7.780	Gain
AGC_Akt_AKT1_ST	P10275	AR	P31749	AKT1	T657	E654K	654	Missense	distal	-3	no	5.796	7.847	EPSD	COSMIC	7.780	Gain
AGC_Akt_AKT1_ST	P10275	AR	P31749	AKT1	S792	G796E	796	Missense	distal	4	no	14.676	14.581	PhosphoSitePlus;EPSD	COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	P10275	AR	P31749	AKT1	S792	L798P	798	Missense	distal	6	no	14.676	14.686	PhosphoSitePlus;EPSD	COSMIC	7.780	Up-regulation
AGC_Akt_AKT1_ST	P10275	AR	P31749	AKT1	S792	Q799E	799	Missense	distal	7	no	14.676	14.690	PhosphoSitePlus;EPSD	COSMIC	7.780	Up-regulation
AGC_Akt_AKT1_ST	P10275	AR	P31749	AKT1	S792	S792F	792	Missense	central	0	yes	14.676	0.000	PhosphoSitePlus;EPSD	COSMIC	7.780	Loss
AGC_Akt_AKT1_ST	P10275	AR	P31749	AKT1	S792	E794G	794	Missense	proximal	2	no	14.676	14.533	PhosphoSitePlus;EPSD	COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	P10275	AR	P31749	AKT1	S792	S792P	792	Missense	central	0	yes	14.676	0.000	PhosphoSitePlus;EPSD	COSMIC	7.780	Loss
AGC_Akt_AKT1_ST	P10275	AR	P31749	AKT1	S792	H790Q	790	Missense	proximal	-2	no	14.676	15.024	PhosphoSitePlus;EPSD	COSMIC	7.780	Up-regulation
AGC_Akt_AKT1_ST	P10275	AR	P31749	AKT1	S792	E794D	794	Missense	proximal	2	no	14.676	14.266	PhosphoSitePlus;EPSD	COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	Q9BRQ0	PYGO2	P31749	AKT1	S48	R45Q	45	Missense	distal	-3	no	14.059	6.848	PhosphoSitePlus	COSMIC	7.780	Loss
AGC_Akt_AKT1_ST	Q9BRQ0	PYGO2	P31749	AKT1	S48	P41L	41	Missense	distal	-7	no	14.059	14.020	PhosphoSitePlus	COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	Q9BRQ0	PYGO2	P31749	AKT1	S48	Q51E	51	Missense	distal	3	no	14.059	14.091	PhosphoSitePlus	COSMIC	7.780	Up-regulation
AGC_Akt_AKT1_ST	Q9BRQ0	PYGO2	P31749	AKT1	S48	A54S	54	Missense	distal	6	no	14.059	14.142	PhosphoSitePlus	COSMIC	7.780	Up-regulation
AGC_Akt_AKT1_ST	Q9BRQ0	PYGO2	P31749	AKT1	T50	R45Q	45	Missense	distal	-5	no	11.889	7.661	EPSD	COSMIC	7.780	Loss
AGC_Akt_AKT1_ST	Q9BRQ0	PYGO2	P31749	AKT1	T50	Q51E	51	Missense	proximal	1	no	11.889	11.943	EPSD	COSMIC	7.780	Up-regulation
AGC_Akt_AKT1_ST	Q9BRQ0	PYGO2	P31749	AKT1	T50	A54S	54	Missense	distal	4	no	11.889	11.765	EPSD	COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	Q9BRQ0	PYGO2	P31749	AKT1	T302	G297R	297	Missense	distal	-5	no	4.154	8.218	EPSD	COSMIC	7.780	Gain
AGC_Akt_AKT1_ST	Q00987	MDM2	P31749	AKT1	T158	P156R	156	Missense	proximal	-2	no	10.861	11.497	EPSD	COSMIC	7.780	Up-regulation
AGC_Akt_AKT1_ST	Q00987	MDM2	P31749	AKT1	T158	R155T	155	Missense	distal	-3	no	10.861	3.840	EPSD	COSMIC	7.780	Loss
AGC_Akt_AKT1_ST	Q00987	MDM2	P31749	AKT1	T158	S160F	160	Missense	proximal	2	no	10.861	10.284	EPSD	COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	Q00987	MDM2	P31749	AKT1	T158	H151Y	151	Missense	distal	-7	no	10.861	10.901	EPSD	COSMIC	7.780	Up-regulation
AGC_Akt_AKT1_ST	Q00987	MDM2	P31749	AKT1	T158	P156S	156	Missense	proximal	-2	no	10.861	11.686	EPSD	COSMIC	7.780	Up-regulation
AGC_Akt_AKT1_ST	Q00987	MDM2	P31749	AKT1	T158	S159R	159	Missense	proximal	1	no	10.861	11.006	EPSD	COSMIC	7.780	Up-regulation
AGC_Akt_AKT1_ST	Q00987	MDM2	P31749	AKT1	T158	S159G	159	Missense	proximal	1	no	10.861	10.557	EPSD	COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	Q00987	MDM2	P31749	AKT1	T158	S159N	159	Missense	proximal	1	no	10.861	10.773	EPSD	COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	Q00987	MDM2	P31749	AKT1	T158	R161T	161	Missense	distal	3	no	10.861	10.877	EPSD	COSMIC	7.780	Up-regulation
AGC_Akt_AKT1_ST	Q00987	MDM2	P31749	AKT1	S160	P156R	156	Missense	distal	-4	no	7.868	8.689	EPSD	COSMIC	7.780	Up-regulation
AGC_Akt_AKT1_ST	Q00987	MDM2	P31749	AKT1	S160	R155T	155	Missense	distal	-5	no	7.868	4.138	EPSD	COSMIC	7.780	Loss
AGC_Akt_AKT1_ST	Q00987	MDM2	P31749	AKT1	S160	S160F	160	Missense	central	0	yes	7.868	0.000	EPSD	COSMIC	7.780	Loss
AGC_Akt_AKT1_ST	Q00987	MDM2	P31749	AKT1	S160	P156S	156	Missense	distal	-4	no	7.868	8.604	EPSD	COSMIC	7.780	Up-regulation
AGC_Akt_AKT1_ST	Q00987	MDM2	P31749	AKT1	S160	S159R	159	Missense	proximal	-1	no	7.868	7.878	EPSD	COSMIC	7.780	Up-regulation
AGC_Akt_AKT1_ST	Q00987	MDM2	P31749	AKT1	S160	S159G	159	Missense	proximal	-1	no	7.868	7.838	EPSD	COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	Q00987	MDM2	P31749	AKT1	S160	S166C	166	Missense	distal	6	no	7.868	7.665	EPSD	COSMIC	7.780	Loss
AGC_Akt_AKT1_ST	Q00987	MDM2	P31749	AKT1	S160	E167Q	167	Missense	distal	7	no	7.868	7.853	EPSD	COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	Q00987	MDM2	P31749	AKT1	S160	S159N	159	Missense	proximal	-1	no	7.868	7.849	EPSD	COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	Q00987	MDM2	P31749	AKT1	S160	R161T	161	Missense	proximal	1	no	7.868	7.916	EPSD	COSMIC	7.780	Up-regulation
AGC_Akt_AKT1_ST	Q00987	MDM2	P31749	AKT1	S160	S166F	166	Missense	distal	6	no	7.868	7.748	EPSD	COSMIC	7.780	Loss
AGC_Akt_AKT1_ST	Q00987	MDM2	P31749	AKT1	S166	E170D	170	Missense	distal	4	no	17.583	17.729	PhosphoSitePlus;EPSD	COSMIC	7.780	Up-regulation
AGC_Akt_AKT1_ST	Q00987	MDM2	P31749	AKT1	S166	S160F	160	Missense	distal	-6	no	17.583	17.509	PhosphoSitePlus;EPSD	COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	Q00987	MDM2	P31749	AKT1	S166	S159R	159	Missense	distal	-7	no	17.583	17.639	PhosphoSitePlus;EPSD	COSMIC	7.780	Up-regulation
AGC_Akt_AKT1_ST	Q00987	MDM2	P31749	AKT1	S166	S159G	159	Missense	distal	-7	no	17.583	17.397	PhosphoSitePlus;EPSD	COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	Q00987	MDM2	P31749	AKT1	S166	D173Y	173	Missense	distal	7	no	17.583	17.617	PhosphoSitePlus;EPSD	COSMIC	7.780	Up-regulation
AGC_Akt_AKT1_ST	Q00987	MDM2	P31749	AKT1	S166	S166C	166	Missense	central	0	yes	17.583	0.000	PhosphoSitePlus;EPSD	COSMIC	7.780	Loss
AGC_Akt_AKT1_ST	Q00987	MDM2	P31749	AKT1	S166	E167Q	167	Missense	proximal	1	no	17.583	17.529	PhosphoSitePlus;EPSD	COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	Q00987	MDM2	P31749	AKT1	S166	S159N	159	Missense	distal	-7	no	17.583	17.469	PhosphoSitePlus;EPSD	COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	Q00987	MDM2	P31749	AKT1	S166	R161T	161	Missense	distal	-5	no	17.583	13.853	PhosphoSitePlus;EPSD	COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	Q00987	MDM2	P31749	AKT1	S166	S166F	166	Missense	central	0	yes	17.583	0.000	PhosphoSitePlus;EPSD	COSMIC	7.780	Loss
AGC_Akt_AKT1_ST	Q00987	MDM2	P31749	AKT1	T168	E170D	170	Missense	proximal	2	no	8.194	7.784	EPSD	COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	Q00987	MDM2	P31749	AKT1	T168	D173Y	173	Missense	distal	5	no	8.194	8.225	EPSD	COSMIC	7.780	Up-regulation
AGC_Akt_AKT1_ST	Q00987	MDM2	P31749	AKT1	T168	S166C	166	Missense	proximal	-2	no	8.194	6.541	EPSD	COSMIC	7.780	Loss
AGC_Akt_AKT1_ST	Q00987	MDM2	P31749	AKT1	T168	E167Q	167	Missense	proximal	-1	no	8.194	8.187	EPSD	COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	Q00987	MDM2	P31749	AKT1	T168	R161T	161	Missense	distal	-7	no	8.194	8.188	EPSD	COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	Q00987	MDM2	P31749	AKT1	T168	S166F	166	Missense	proximal	-2	no	8.194	7.327	EPSD	COSMIC	7.780	Loss
AGC_Akt_AKT1_ST	Q00987	MDM2	P31749	AKT1	S186	R183H	183	Missense	distal	-3	no	15.851	11.153	EPSD;PhosphoSitePlus	COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	Q00987	MDM2	P31749	AKT1	S186	I189V	189	Missense	distal	3	no	15.851	15.892	EPSD;PhosphoSitePlus	COSMIC	7.780	Up-regulation
AGC_Akt_AKT1_ST	Q00987	MDM2	P31749	AKT1	S186	K185R	185	Missense	proximal	-1	no	15.851	15.855	EPSD;PhosphoSitePlus	COSMIC	7.780	Up-regulation
AGC_Akt_AKT1_ST	Q00987	MDM2	P31749	AKT1	S186	S190F	190	Missense	distal	4	no	15.851	16.047	EPSD;PhosphoSitePlus	COSMIC	7.780	Up-regulation
AGC_Akt_AKT1_ST	Q00987	MDM2	P31749	AKT1	S186	R183C	183	Missense	distal	-3	no	15.851	9.678	EPSD;PhosphoSitePlus	COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	Q00987	MDM2	P31749	AKT1	S186	R179P	179	Missense	distal	-7	no	15.851	15.601	EPSD;PhosphoSitePlus	COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	Q00987	MDM2	P31749	AKT1	S188	R183H	183	Missense	distal	-5	no	11.766	8.671	EPSD;PhosphoSitePlus	COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	Q00987	MDM2	P31749	AKT1	S188	I189V	189	Missense	proximal	1	no	11.766	12.013	EPSD;PhosphoSitePlus	COSMIC	7.780	Up-regulation
AGC_Akt_AKT1_ST	Q00987	MDM2	P31749	AKT1	S188	K185R	185	Missense	distal	-3	no	11.766	16.286	EPSD;PhosphoSitePlus	COSMIC	7.780	Up-regulation
AGC_Akt_AKT1_ST	Q00987	MDM2	P31749	AKT1	S188	S190F	190	Missense	proximal	2	no	11.766	11.188	EPSD;PhosphoSitePlus	COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	Q00987	MDM2	P31749	AKT1	S188	R183C	183	Missense	distal	-5	no	11.766	7.689	EPSD;PhosphoSitePlus	COSMIC	7.780	Loss
AGC_Akt_AKT1_ST	Q00987	MDM2	P31749	AKT1	S190	R183H	183	Missense	distal	-7	no	9.490	9.189	EPSD	COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	Q00987	MDM2	P31749	AKT1	S190	I189V	189	Missense	proximal	-1	no	9.490	9.505	EPSD	COSMIC	7.780	Up-regulation
AGC_Akt_AKT1_ST	Q00987	MDM2	P31749	AKT1	S190	K185R	185	Missense	distal	-5	no	9.490	11.888	EPSD	COSMIC	7.780	Up-regulation
AGC_Akt_AKT1_ST	Q00987	MDM2	P31749	AKT1	S190	S190F	190	Missense	central	0	yes	9.490	0.000	EPSD	COSMIC	7.780	Loss
AGC_Akt_AKT1_ST	Q00987	MDM2	P31749	AKT1	S190	R183C	183	Missense	distal	-7	no	9.490	9.011	EPSD	COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	Q00987	MDM2	P31749	AKT1	S190	S196F	196	Missense	distal	6	no	9.490	9.371	EPSD	COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	Q00987	MDM2	P31749	AKT1	S246	D243H	243	Missense	distal	-3	no	6.807	8.059	EPSD	COSMIC	7.780	Gain
AGC_Akt_AKT1_ST	Q00987	MDM2	P31749	AKT1	S290	E285K	285	Missense	distal	-5	no	7.136	8.833	EPSD	COSMIC	7.780	Gain
AGC_Akt_AKT1_ST	Q00987	MDM2	P31749	AKT1	T419	E413K	413	Missense	distal	-6	no	11.535	11.601	EPSD	COSMIC	7.780	Up-regulation
AGC_Akt_AKT1_ST	Q00987	MDM2	P31749	AKT1	T419	E413G	413	Missense	distal	-6	no	11.535	11.502	EPSD	COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	Q00987	MDM2	P31749	AKT1	T419	E415Q	415	Missense	distal	-4	no	11.535	11.511	EPSD	COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	Q00987	MDM2	P31749	AKT1	T419	T419I	419	Missense	central	0	yes	11.535	0.000	EPSD	COSMIC	7.780	Loss
AGC_Akt_AKT1_ST	Q00987	MDM2	P31749	AKT1	T419	S425C	425	Missense	distal	6	no	11.535	11.332	EPSD	COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	Q00987	MDM2	P31749	AKT1	T419	F414I	414	Missense	distal	-5	no	11.535	10.489	EPSD	COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	Q00987	MDM2	P31749	AKT1	T419	V426A	426	Missense	distal	7	no	11.535	11.539	EPSD	COSMIC	7.780	Up-regulation
AGC_Akt_AKT1_ST	Q96B36	AKT1S1	P31749	AKT1	T73	P78A	78	Missense	distal	5	no	11.218	11.220	EPSD	COSMIC	7.780	Up-regulation
AGC_Akt_AKT1_ST	Q96B36	AKT1S1	P31749	AKT1	T73	A74T	74	Missense	proximal	1	no	11.218	11.485	EPSD	COSMIC	7.780	Up-regulation
AGC_Akt_AKT1_ST	Q96B36	AKT1S1	P31749	AKT1	T73	A79S	79	Missense	distal	6	no	11.218	11.300	EPSD	COSMIC	7.780	Up-regulation
AGC_Akt_AKT1_ST	Q96B36	AKT1S1	P31749	AKT1	T73	A79V	79	Missense	distal	6	no	11.218	11.186	EPSD	COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	Q96B36	AKT1S1	P31749	AKT1	T73	R76Q	76	Missense	distal	3	no	11.218	11.162	EPSD	COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	Q96B36	AKT1S1	P31749	AKT1	T73	P78S	78	Missense	distal	5	no	11.218	11.271	EPSD	COSMIC	7.780	Up-regulation
AGC_Akt_AKT1_ST	Q96B36	AKT1S1	P31749	AKT1	S202	D204N	204	Missense	proximal	2	no	10.870	11.200	EPSD	COSMIC	7.780	Up-regulation
AGC_Akt_AKT1_ST	Q96B36	AKT1S1	P31749	AKT1	S202	A200V	200	Missense	proximal	-2	no	10.870	10.132	EPSD	COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	Q96B36	AKT1S1	P31749	AKT1	S202	E205K	205	Missense	distal	3	no	10.870	10.914	EPSD	COSMIC	7.780	Up-regulation
AGC_Akt_AKT1_ST	Q96B36	AKT1S1	P31749	AKT1	S202	T198I	198	Missense	distal	-4	no	10.870	9.433	EPSD	COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	Q96B36	AKT1S1	P31749	AKT1	S202	R201W	201	Missense	proximal	-1	no	10.870	10.809	EPSD	COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	Q96B36	AKT1S1	P31749	AKT1	S202	T198A	198	Missense	distal	-4	no	10.870	10.092	EPSD	COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	Q96B36	AKT1S1	P31749	AKT1	S202	S203L	203	Missense	proximal	1	no	10.870	10.969	EPSD	COSMIC	7.780	Up-regulation
AGC_Akt_AKT1_ST	Q96B36	AKT1S1	P31749	AKT1	S202	P209L	209	Missense	distal	7	no	10.870	10.862	EPSD	COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	Q96B36	AKT1S1	P31749	AKT1	S203	E205K	205	Missense	proximal	2	no	7.628	7.833	EPSD	COSMIC	7.780	Gain
AGC_Akt_AKT1_ST	Q96B36	AKT1S1	P31749	AKT1	T233	V226E	226	Missense	distal	-7	no	9.167	9.294	EPSD	COSMIC	7.780	Up-regulation
AGC_Akt_AKT1_ST	Q13950	RUNX2	P31749	AKT1	S28	P29H	29	Missense	proximal	1	no	13.000	12.978	EPSD;PhosphoSitePlus	COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	Q13950	RUNX2	P31749	AKT1	S31	P36S	36	Missense	distal	5	no	8.646	8.699	EPSD	COSMIC	7.780	Up-regulation
AGC_Akt_AKT1_ST	Q13950	RUNX2	P31749	AKT1	S31	P29H	29	Missense	proximal	-2	no	8.646	8.421	EPSD	COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	Q13950	RUNX2	P31749	AKT1	S32	P29H	29	Missense	distal	-3	no	5.858	7.799	EPSD	COSMIC	7.780	Gain
AGC_Akt_AKT1_ST	Q13950	RUNX2	P31749	AKT1	S118	D117N	117	Missense	proximal	-1	no	11.719	11.749	EPSD	COSMIC	7.780	Up-regulation
AGC_Akt_AKT1_ST	Q13950	RUNX2	P31749	AKT1	S118	L122M	122	Missense	distal	4	no	11.719	11.695	EPSD	COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	Q13950	RUNX2	P31749	AKT1	S196	G189C	189	Missense	distal	-7	no	11.166	10.929	EPSD;PhosphoSitePlus	COSMIC;CCLE	7.780	Down-regulation
AGC_Akt_AKT1_ST	Q13950	RUNX2	P31749	AKT1	S196	V203F	203	Missense	distal	7	no	11.166	11.147	EPSD;PhosphoSitePlus	COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	Q13950	RUNX2	P31749	AKT1	S196	G192E	192	Missense	distal	-4	no	11.166	11.383	EPSD;PhosphoSitePlus	COSMIC	7.780	Up-regulation
AGC_Akt_AKT1_ST	Q13950	RUNX2	P31749	AKT1	T198	V203F	203	Missense	distal	5	no	10.635	10.622	EPSD;PhosphoSitePlus	COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	Q13950	RUNX2	P31749	AKT1	T198	G192E	192	Missense	distal	-6	no	10.635	10.668	EPSD;PhosphoSitePlus	COSMIC	7.780	Up-regulation
AGC_Akt_AKT1_ST	Q13950	RUNX2	P31749	AKT1	T220	V221E	221	Missense	proximal	1	no	8.535	8.440	EPSD	COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	Q13950	RUNX2	P31749	AKT1	T220	Y213H	213	Missense	distal	-7	no	8.535	8.496	EPSD	COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	Q13950	RUNX2	P31749	AKT1	T220	R215G	215	Missense	distal	-5	no	8.535	4.471	EPSD	COSMIC	7.780	Loss
AGC_Akt_AKT1_ST	Q13950	RUNX2	P31749	AKT1	S294	S293P	293	Missense	proximal	-1	no	8.071	8.042	EPSD	COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	Q13950	RUNX2	P31749	AKT1	S294	S298F	298	Missense	distal	4	no	8.071	8.267	EPSD	COSMIC	7.780	Up-regulation
AGC_Akt_AKT1_ST	Q13950	RUNX2	P31749	AKT1	S340	R338C	338	Missense	proximal	-2	no	9.152	7.687	EPSD	COSMIC	7.780	Loss
AGC_Akt_AKT1_ST	Q13950	RUNX2	P31749	AKT1	S340	A345D	345	Missense	distal	5	no	9.152	9.128	EPSD	COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	Q13950	RUNX2	P31749	AKT1	S503	S503F	503	Missense	central	0	yes	8.669	0.000	EPSD	COSMIC	7.780	Loss
AGC_Akt_AKT1_ST	Q13950	RUNX2	P31749	AKT1	S503	A496T	496	Missense	distal	-7	no	8.669	8.869	EPSD	COSMIC	7.780	Up-regulation
AGC_Akt_AKT1_ST	O60825	PFKFB2	P31749	AKT1	S29	S32C	32	Missense	distal	3	no	8.511	8.334	EPSD	COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	O60825	PFKFB2	P31749	AKT1	S29	M34T	34	Missense	distal	5	no	8.511	8.568	EPSD	COSMIC	7.780	Up-regulation
AGC_Akt_AKT1_ST	O60825	PFKFB2	P31749	AKT1	T52	T52A	52	Missense	central	0	yes	10.138	0.000	EPSD	COSMIC	7.780	Loss
AGC_Akt_AKT1_ST	O60825	PFKFB2	P31749	AKT1	T52	G45D	45	Missense	distal	-7	no	10.138	9.953	EPSD	COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	O60825	PFKFB2	P31749	AKT1	T59	I65V	65	Missense	distal	6	no	8.764	8.815	EPSD	COSMIC	7.780	Up-regulation
AGC_Akt_AKT1_ST	O60825	PFKFB2	P31749	AKT1	T59	T52A	52	Missense	distal	-7	no	8.764	8.565	EPSD	COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	O60825	PFKFB2	P31749	AKT1	T59	R60H	60	Missense	proximal	1	no	8.764	8.442	EPSD	COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	O60825	PFKFB2	P31749	AKT1	T59	W64L	64	Missense	distal	5	no	8.764	8.785	EPSD	COSMIC	7.780	Up-regulation
AGC_Akt_AKT1_ST	O60825	PFKFB2	P31749	AKT1	S84	A81S	81	Missense	distal	-3	no	8.731	7.258	EPSD	COSMIC	7.780	Loss
AGC_Akt_AKT1_ST	O60825	PFKFB2	P31749	AKT1	S84	V82A	82	Missense	proximal	-2	no	8.731	9.469	EPSD	COSMIC	7.780	Up-regulation
AGC_Akt_AKT1_ST	O60825	PFKFB2	P31749	AKT1	S84	S84Y	84	Missense	central	0	yes	8.731	0.000	EPSD	COSMIC	7.780	Loss
AGC_Akt_AKT1_ST	O60825	PFKFB2	P31749	AKT1	S84	F91C	91	Missense	distal	7	no	8.731	8.682	EPSD	COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	O60825	PFKFB2	P31749	AKT1	S466	V460L	460	Missense	distal	-6	no	16.116	16.141	PhosphoSitePlus;EPSD	COSMIC	7.780	Up-regulation
AGC_Akt_AKT1_ST	O60825	PFKFB2	P31749	AKT1	S466	S473L	473	Missense	distal	7	no	16.116	16.049	PhosphoSitePlus;EPSD	COSMIC;GDSC	7.780	Down-regulation
AGC_Akt_AKT1_ST	O60825	PFKFB2	P31749	AKT1	S466	R461S	461	Missense	distal	-5	no	16.116	11.645	PhosphoSitePlus;EPSD	COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	O60825	PFKFB2	P31749	AKT1	S466	R461C	461	Missense	distal	-5	no	16.116	12.039	PhosphoSitePlus;EPSD	COSMIC;GDSC	7.780	Down-regulation
AGC_Akt_AKT1_ST	O60825	PFKFB2	P31749	AKT1	S466	S466F	466	Missense	central	0	yes	16.116	0.000	PhosphoSitePlus;EPSD	COSMIC	7.780	Loss
AGC_Akt_AKT1_ST	O60825	PFKFB2	P31749	AKT1	T468	S473L	473	Missense	distal	5	no	7.975	7.909	EPSD	COSMIC;GDSC	7.780	Down-regulation
AGC_Akt_AKT1_ST	O60825	PFKFB2	P31749	AKT1	T468	R461S	461	Missense	distal	-7	no	7.975	7.919	EPSD	COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	O60825	PFKFB2	P31749	AKT1	T468	R461C	461	Missense	distal	-7	no	7.975	7.496	EPSD	COSMIC;GDSC	7.780	Loss
AGC_Akt_AKT1_ST	O60825	PFKFB2	P31749	AKT1	T468	S466F	466	Missense	proximal	-2	no	7.975	7.108	EPSD	COSMIC	7.780	Loss
AGC_Akt_AKT1_ST	O60825	PFKFB2	P31749	AKT1	S483	K490N	490	Missense	distal	7	no	16.631	16.596	EPSD;PhosphoSitePlus	COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	O60825	PFKFB2	P31749	AKT1	S483	R478P	478	Missense	distal	-5	no	16.631	12.621	EPSD;PhosphoSitePlus	COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	O60825	PFKFB2	P31749	AKT1	S493	R496H	496	Missense	distal	3	no	8.042	7.958	EPSD	COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	O60825	PFKFB2	P31749	AKT1	S493	P491S	491	Missense	proximal	-2	no	8.042	8.866	EPSD	COSMIC	7.780	Up-regulation
AGC_Akt_AKT1_ST	O60825	PFKFB2	P31749	AKT1	S493	K490N	490	Missense	distal	-3	no	8.042	5.086	EPSD	COSMIC	7.780	Loss
AGC_Akt_AKT1_ST	O60825	PFKFB2	P31749	AKT1	S493	R496S	496	Missense	distal	3	no	8.042	8.059	EPSD	COSMIC	7.780	Up-regulation
AGC_Akt_AKT1_ST	O60825	PFKFB2	P31749	AKT1	S493	S493N	493	Missense	central	0	yes	8.042	0.000	EPSD	COSMIC	7.780	Loss
AGC_Akt_AKT1_ST	Q14CB8	ARHGAP19	P31749	AKT1	S358	R355Q	355	Missense	distal	-3	no	14.787	7.575	EPSD	COSMIC;GDSC	7.780	Loss
AGC_Akt_AKT1_ST	Q14CB8	ARHGAP19	P31749	AKT1	S358	R355W	355	Missense	distal	-3	no	14.787	5.846	EPSD	COSMIC	7.780	Loss
AGC_Akt_AKT1_ST	Q14CB8	ARHGAP19	P31749	AKT1	S420	S420C	420	Missense	central	0	yes	13.320	0.000	EPSD	COSMIC	7.780	Loss
AGC_Akt_AKT1_ST	Q14CB8	ARHGAP19	P31749	AKT1	S422	S420C	420	Missense	proximal	-2	no	15.684	14.032	PhosphoSitePlus	COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	Q14CB8	ARHGAP19	P31749	AKT1	S424	S420C	420	Missense	distal	-4	no	16.448	14.855	EPSD	COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	Q14CB8	ARHGAP19	P31749	AKT1	S424	V431G	431	Missense	distal	7	no	16.448	16.430	EPSD	COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	Q14CB8	ARHGAP19	P31749	AKT1	T446	S449C	449	Missense	distal	3	no	8.349	8.172	EPSD	COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	Q14CB8	ARHGAP19	P31749	AKT1	S468	L465I	465	Missense	distal	-3	no	9.604	9.516	EPSD	COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	Q14CB8	ARHGAP19	P31749	AKT1	S468	L465F	465	Missense	distal	-3	no	9.604	11.003	EPSD	COSMIC	7.780	Up-regulation
AGC_Akt_AKT1_ST	Q96ST2	IWS1	P31749	AKT1	S157	A156V	156	Missense	proximal	-1	no	7.937	7.922	EPSD	COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	Q96ST2	IWS1	P31749	AKT1	S157	P155S	155	Missense	proximal	-2	no	7.937	8.761	EPSD	COSMIC	7.780	Up-regulation
AGC_Akt_AKT1_ST	Q96ST2	IWS1	P31749	AKT1	S157	E160K	160	Missense	distal	3	no	7.937	7.980	EPSD	COSMIC	7.780	Up-regulation
AGC_Akt_AKT1_ST	Q96ST2	IWS1	P31749	AKT1	S235	N239K	239	Missense	distal	4	no	7.817	7.685	EPSD	COSMIC	7.780	Loss
AGC_Akt_AKT1_ST	Q96ST2	IWS1	P31749	AKT1	S235	R231G	231	Missense	distal	-4	no	7.817	7.002	EPSD	COSMIC	7.780	Loss
AGC_Akt_AKT1_ST	Q96ST2	IWS1	P31749	AKT1	S329	D334N	334	Missense	distal	5	no	8.673	8.713	EPSD	COSMIC	7.780	Up-regulation
AGC_Akt_AKT1_ST	Q96ST2	IWS1	P31749	AKT1	S329	K326R	326	Missense	distal	-3	no	8.673	13.193	EPSD	COSMIC	7.780	Up-regulation
AGC_Akt_AKT1_ST	Q96ST2	IWS1	P31749	AKT1	S415	D416N	416	Missense	proximal	1	no	12.216	12.340	EPSD	COSMIC	7.780	Up-regulation
AGC_Akt_AKT1_ST	Q96ST2	IWS1	P31749	AKT1	T435	S429L	429	Missense	distal	-6	no	11.271	11.220	EPSD	COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	Q96ST2	IWS1	P31749	AKT1	S511	E507K	507	Missense	distal	-4	no	8.095	8.679	EPSD	COSMIC	7.780	Up-regulation
AGC_Akt_AKT1_ST	O60285	NUAK1	P31749	AKT1	S266	I262T	262	Missense	distal	-4	no	11.701	13.139	EPSD	COSMIC	7.780	Up-regulation
AGC_Akt_AKT1_ST	O60285	NUAK1	P31749	AKT1	S266	G268E	268	Missense	proximal	2	no	11.701	11.844	EPSD	COSMIC	7.780	Up-regulation
AGC_Akt_AKT1_ST	O60285	NUAK1	P31749	AKT1	S266	R271L	271	Missense	distal	5	no	11.701	11.627	EPSD	COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	O60285	NUAK1	P31749	AKT1	S266	R271W	271	Missense	distal	5	no	11.701	11.606	EPSD	COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	O60285	NUAK1	P31749	AKT1	S413	G415S	415	Missense	proximal	2	no	11.837	12.169	EPSD	COSMIC	7.780	Up-regulation
AGC_Akt_AKT1_ST	O60285	NUAK1	P31749	AKT1	S413	V420L	420	Missense	distal	7	no	11.837	11.826	EPSD	COSMIC;GDSC;CCLE	7.780	Down-regulation
AGC_Akt_AKT1_ST	O60285	NUAK1	P31749	AKT1	S566	R563L	563	Missense	distal	-3	no	12.954	5.960	EPSD	COSMIC	7.780	Loss
AGC_Akt_AKT1_ST	O60285	NUAK1	P31749	AKT1	S570	R563L	563	Missense	distal	-7	no	12.692	12.403	EPSD	COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	O60285	NUAK1	P31749	AKT1	S570	S576N	576	Missense	distal	6	no	12.692	12.625	EPSD	COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	O60285	NUAK1	P31749	AKT1	S600	R595H	595	Missense	distal	-5	no	14.420	11.325	PhosphoSitePlus	COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	O60285	NUAK1	P31749	AKT1	S600	S603F	603	Missense	distal	3	no	14.420	14.322	PhosphoSitePlus	COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	O60285	NUAK1	P31749	AKT1	S600	P593T	593	Missense	distal	-7	no	14.420	14.665	PhosphoSitePlus	COSMIC	7.780	Up-regulation
AGC_Akt_AKT1_ST	O60285	NUAK1	P31749	AKT1	S600	F607V	607	Missense	distal	7	no	14.420	14.439	PhosphoSitePlus	COSMIC	7.780	Up-regulation
AGC_Akt_AKT1_ST	O60285	NUAK1	P31749	AKT1	S636	R629W	629	Missense	distal	-7	no	8.216	7.793	EPSD	COSMIC;GDSC	7.780	Down-regulation
AGC_Akt_AKT1_ST	O60285	NUAK1	P31749	AKT1	S636	F637V	637	Missense	proximal	1	no	8.216	8.197	EPSD	COSMIC;GDSC;CCLE	7.780	Down-regulation
AGC_Akt_AKT1_ST	O60285	NUAK1	P31749	AKT1	S636	R629Q	629	Missense	distal	-7	no	8.216	8.022	EPSD	COSMIC;CCLE	7.780	Down-regulation
AGC_Akt_AKT1_ST	Q5XUX0	FBXO31	P31749	AKT1	T103	R99H	99	Missense	distal	-4	no	9.387	8.328	EPSD	COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	Q5XUX0	FBXO31	P31749	AKT1	T127	G128D	128	Missense	proximal	1	no	8.142	8.234	EPSD	COSMIC	7.780	Up-regulation
AGC_Akt_AKT1_ST	Q5XUX0	FBXO31	P31749	AKT1	T127	G128V	128	Missense	proximal	1	no	8.142	8.446	EPSD	COSMIC	7.780	Up-regulation
AGC_Akt_AKT1_ST	Q5XUX0	FBXO31	P31749	AKT1	T127	G128S	128	Missense	proximal	1	no	8.142	8.447	EPSD	COSMIC	7.780	Up-regulation
AGC_Akt_AKT1_ST	Q5XUX0	FBXO31	P31749	AKT1	S403	P404L	404	Missense	proximal	1	no	8.709	8.963	EPSD	COSMIC;GDSC;CCLE	7.780	Up-regulation
AGC_Akt_AKT1_ST	Q5XUX0	FBXO31	P31749	AKT1	S403	R398G	398	Missense	distal	-5	no	8.709	4.645	EPSD	COSMIC	7.780	Loss
AGC_Akt_AKT1_ST	Q5XUX0	FBXO31	P31749	AKT1	S403	P404S	404	Missense	proximal	1	no	8.709	8.864	EPSD	COSMIC	7.780	Up-regulation
AGC_Akt_AKT1_ST	Q5XUX0	FBXO31	P31749	AKT1	S403	A405S	405	Missense	proximal	2	no	8.709	9.085	EPSD	COSMIC	7.780	Up-regulation
AGC_Akt_AKT1_ST	Q9Y283	INVS	P31749	AKT1	S700	G698S	698	Missense	proximal	-2	no	8.086	8.781	EPSD	COSMIC	7.780	Up-regulation
AGC_Akt_AKT1_ST	Q9Y283	INVS	P31749	AKT1	T864	S868C	868	Missense	distal	4	no	12.036	12.381	EPSD;PhosphoSitePlus	COSMIC	7.780	Up-regulation
AGC_Akt_AKT1_ST	Q9Y283	INVS	P31749	AKT1	T864	R861M	861	Missense	distal	-3	no	12.036	4.530	EPSD;PhosphoSitePlus	COSMIC	7.780	Loss
AGC_Akt_AKT1_ST	Q9Y283	INVS	P31749	AKT1	T864	D870N	870	Missense	distal	6	no	12.036	12.118	EPSD;PhosphoSitePlus	COSMIC	7.780	Up-regulation
AGC_Akt_AKT1_ST	Q9Y283	INVS	P31749	AKT1	T864	L867M	867	Missense	distal	3	no	12.036	12.049	EPSD;PhosphoSitePlus	COSMIC	7.780	Up-regulation
AGC_Akt_AKT1_ST	Q9Y283	INVS	P31749	AKT1	S865	S868C	868	Missense	distal	3	no	10.087	9.910	EPSD;PhosphoSitePlus	COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	Q9Y283	INVS	P31749	AKT1	S865	R861M	861	Missense	distal	-4	no	10.087	9.092	EPSD;PhosphoSitePlus	COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	Q9Y283	INVS	P31749	AKT1	S865	D870N	870	Missense	distal	5	no	10.087	10.127	EPSD;PhosphoSitePlus	COSMIC	7.780	Up-regulation
AGC_Akt_AKT1_ST	Q9Y283	INVS	P31749	AKT1	S865	L867M	867	Missense	proximal	2	no	10.087	10.216	EPSD;PhosphoSitePlus	COSMIC	7.780	Up-regulation
AGC_Akt_AKT1_ST	Q9Y283	INVS	P31749	AKT1	T866	S868C	868	Missense	proximal	2	no	9.905	9.080	PhosphoSitePlus;EPSD	COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	Q9Y283	INVS	P31749	AKT1	T866	R861M	861	Missense	distal	-5	no	9.905	5.383	PhosphoSitePlus;EPSD	COSMIC	7.780	Loss
AGC_Akt_AKT1_ST	Q9Y283	INVS	P31749	AKT1	T866	D870N	870	Missense	distal	4	no	9.905	9.790	PhosphoSitePlus;EPSD	COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	Q9Y283	INVS	P31749	AKT1	T866	L867M	867	Missense	proximal	1	no	9.905	9.743	PhosphoSitePlus;EPSD	COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	Q9Y283	INVS	P31749	AKT1	S1019	H1015N	1015	Missense	distal	-4	no	7.616	8.022	EPSD	COSMIC	7.780	Gain
AGC_Akt_AKT1_ST	Q9Y283	INVS	P31749	AKT1	S1023	R1027C	1027	Missense	distal	4	no	9.831	10.165	EPSD	COSMIC;CCLE	7.780	Up-regulation
AGC_Akt_AKT1_ST	Q9Y283	INVS	P31749	AKT1	S1030	R1027C	1027	Missense	distal	-3	no	9.814	3.641	EPSD	COSMIC;CCLE	7.780	Loss
AGC_Akt_AKT1_ST	Q9Y283	INVS	P31749	AKT1	S1030	L1034I	1034	Missense	distal	4	no	9.814	9.887	EPSD	COSMIC	7.780	Up-regulation
AGC_Akt_AKT1_ST	Q9Y283	INVS	P31749	AKT1	S1030	Q1035H	1035	Missense	distal	5	no	9.814	9.791	EPSD	COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	Q9Y283	INVS	P31749	AKT1	S1030	I1037T	1037	Missense	distal	7	no	9.814	9.922	EPSD	COSMIC	7.780	Up-regulation
AGC_Akt_AKT1_ST	Q9Y283	INVS	P31749	AKT1	S1032	R1027C	1027	Missense	distal	-5	no	8.309	4.232	EPSD	COSMIC;CCLE	7.780	Loss
AGC_Akt_AKT1_ST	Q9Y283	INVS	P31749	AKT1	S1032	L1034I	1034	Missense	proximal	2	no	8.309	8.198	EPSD	COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	Q9Y283	INVS	P31749	AKT1	S1032	Q1035H	1035	Missense	distal	3	no	8.309	8.281	EPSD	COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	Q9Y283	INVS	P31749	AKT1	S1032	I1037T	1037	Missense	distal	5	no	8.309	8.406	EPSD	COSMIC	7.780	Up-regulation
AGC_Akt_AKT1_ST	Q9Y283	INVS	P31749	AKT1	S1050	Y1051D	1051	Missense	proximal	1	no	14.182	13.977	EPSD	COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	Q9Y283	INVS	P31749	AKT1	S1050	L1053M	1053	Missense	distal	3	no	14.182	14.195	EPSD	COSMIC	7.780	Up-regulation
AGC_Akt_AKT1_ST	Q9Y283	INVS	P31749	AKT1	S1050	Q1054P	1054	Missense	distal	4	no	14.182	14.204	EPSD	COSMIC	7.780	Up-regulation
AGC_Akt_AKT1_ST	Q9Y283	INVS	P31749	AKT1	S1050	S1046P	1046	Missense	distal	-4	no	14.182	13.446	EPSD	COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	Q9UPY5	SLC7A11	P31749	AKT1	S26	P33H	33	Missense	distal	7	no	10.440	10.434	PhosphoSitePlus	COSMIC;GDSC;CCLE	7.780	Down-regulation
AGC_Akt_AKT1_ST	Q9UPY5	SLC7A11	P31749	AKT1	S26	P33T	33	Missense	distal	7	no	10.440	10.509	PhosphoSitePlus	COSMIC	7.780	Up-regulation
AGC_Akt_AKT1_ST	O43524	FOXO3	P31749	AKT1	S30	R29L	29	Missense	proximal	-1	no	10.570	10.531	EPSD	COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	O43524	FOXO3	P31749	AKT1	T32	R29L	29	Missense	distal	-3	no	15.456	8.462	PhosphoSitePlus;EPSD	COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	O43524	FOXO3	P31749	AKT1	S75	M77L	77	Missense	proximal	2	no	12.604	12.475	EPSD	COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	O43524	FOXO3	P31749	AKT1	S253	S253F	253	Missense	central	0	yes	16.516	0.000	EPSD;PhosphoSitePlus	COSMIC	7.780	Loss
AGC_Akt_AKT1_ST	O43524	FOXO3	P31749	AKT1	S253	R248W	248	Missense	distal	-5	no	16.516	10.996	EPSD;PhosphoSitePlus	COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	O43524	FOXO3	P31749	AKT1	S280	Q275R	275	Missense	distal	-5	no	4.318	8.545	EPSD	COSMIC	7.780	Gain
AGC_Akt_AKT1_ST	O43524	FOXO3	P31749	AKT1	T313	S318C	318	Missense	distal	5	no	10.817	10.698	EPSD	COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	O43524	FOXO3	P31749	AKT1	S315	S318C	318	Missense	distal	3	no	16.048	15.871	EPSD	COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	O43524	FOXO3	P31749	AKT1	S413	F414Y	414	Missense	proximal	1	no	11.407	11.382	EPSD	COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	O43524	FOXO3	P31749	AKT1	S551	M557R	557	Missense	distal	6	no	11.257	11.354	EPSD	COSMIC	7.780	Up-regulation
AGC_Akt_AKT1_ST	O43524	FOXO3	P31749	AKT1	S553	M557R	557	Missense	distal	4	no	9.351	9.199	EPSD	COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	P46527	CDKN1B	P31749	AKT1	S10	R5L	5	Missense	distal	-5	no	9.798	5.672	EPSD;PhosphoSitePlus	COSMIC	7.780	Loss
AGC_Akt_AKT1_ST	P46527	CDKN1B	P31749	AKT1	S10	E14K	14	Missense	distal	4	no	9.798	9.697	EPSD;PhosphoSitePlus	COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	P46527	CDKN1B	P31749	AKT1	S10	M16T	16	Missense	distal	6	no	9.798	9.917	EPSD;PhosphoSitePlus	COSMIC	7.780	Up-regulation
AGC_Akt_AKT1_ST	P46527	CDKN1B	P31749	AKT1	S10	N3D	3	Missense	distal	-7	no	9.798	9.540	EPSD;PhosphoSitePlus	COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	P46527	CDKN1B	P31749	AKT1	S10	P11S	11	Missense	proximal	1	no	9.798	9.953	EPSD;PhosphoSitePlus	COSMIC	7.780	Up-regulation
AGC_Akt_AKT1_ST	P46527	CDKN1B	P31749	AKT1	S10	S12N	12	Missense	proximal	2	no	9.798	9.529	EPSD;PhosphoSitePlus	COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	P46527	CDKN1B	P31749	AKT1	S10	D17E	17	Missense	distal	7	no	9.798	9.841	EPSD;PhosphoSitePlus	COSMIC	7.780	Up-regulation
AGC_Akt_AKT1_ST	P46527	CDKN1B	P31749	AKT1	S110	Q107R	107	Missense	distal	-3	no	3.421	10.633	EPSD	COSMIC	7.780	Gain
AGC_Akt_AKT1_ST	P46527	CDKN1B	P31749	AKT1	T157	A156V	156	Missense	proximal	-1	no	13.829	13.815	PhosphoSitePlus;EPSD	COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	P46527	CDKN1B	P31749	AKT1	T157	D158Y	158	Missense	proximal	1	no	13.829	14.035	PhosphoSitePlus;EPSD	COSMIC	7.780	Up-regulation
AGC_Akt_AKT1_ST	P46527	CDKN1B	P31749	AKT1	T157	T157N	157	Missense	central	0	yes	13.829	0.000	PhosphoSitePlus;EPSD	COSMIC	7.780	Loss
AGC_Akt_AKT1_ST	P46527	CDKN1B	P31749	AKT1	T157	D159Y	159	Missense	proximal	2	no	13.829	14.056	PhosphoSitePlus;EPSD	COSMIC	7.780	Up-regulation
AGC_Akt_AKT1_ST	P46527	CDKN1B	P31749	AKT1	T157	S161F	161	Missense	distal	4	no	13.829	14.025	PhosphoSitePlus;EPSD	COSMIC	7.780	Up-regulation
AGC_Akt_AKT1_ST	P46527	CDKN1B	P31749	AKT1	T170	N168K	168	Missense	proximal	-2	no	7.441	8.378	EPSD	COSMIC	7.780	Gain
AGC_Akt_AKT1_ST	P46527	CDKN1B	P31749	AKT1	T198	R194K	194	Missense	distal	-4	no	12.810	12.797	EPSD;PhosphoSitePlus	COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	P84103	SRSF3	P31749	AKT1	S95	R90S	90	Missense	distal	-5	no	8.835	4.364	EPSD	COSMIC	7.780	Loss
AGC_Akt_AKT1_ST	P84103	SRSF3	P31749	AKT1	S124	S130F	130	Missense	distal	6	no	10.269	10.149	EPSD	COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	P84103	SRSF3	P31749	AKT1	S126	D132V	132	Missense	distal	6	no	13.180	13.215	EPSD	COSMIC	7.780	Up-regulation
AGC_Akt_AKT1_ST	P84103	SRSF3	P31749	AKT1	S126	S130F	130	Missense	distal	4	no	13.180	13.376	EPSD	COSMIC	7.780	Up-regulation
AGC_Akt_AKT1_ST	P84103	SRSF3	P31749	AKT1	S128	D132V	132	Missense	distal	4	no	17.309	17.264	PhosphoSitePlus;EPSD	COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	P84103	SRSF3	P31749	AKT1	S128	S130F	130	Missense	proximal	2	no	17.309	16.732	PhosphoSitePlus;EPSD	COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	P84103	SRSF3	P31749	AKT1	S128	R134K	134	Missense	distal	6	no	17.309	17.321	PhosphoSitePlus;EPSD	COSMIC	7.780	Up-regulation
AGC_Akt_AKT1_ST	P84103	SRSF3	P31749	AKT1	S128	R134G	134	Missense	distal	6	no	17.309	17.205	PhosphoSitePlus;EPSD	COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	P84103	SRSF3	P31749	AKT1	S130	D132V	132	Missense	proximal	2	no	16.169	16.230	EPSD;PhosphoSitePlus	COSMIC	7.780	Up-regulation
AGC_Akt_AKT1_ST	P84103	SRSF3	P31749	AKT1	S130	S130F	130	Missense	central	0	yes	16.169	0.000	EPSD;PhosphoSitePlus	COSMIC	7.780	Loss
AGC_Akt_AKT1_ST	P84103	SRSF3	P31749	AKT1	S130	R134K	134	Missense	distal	4	no	16.169	16.136	EPSD;PhosphoSitePlus	COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	P84103	SRSF3	P31749	AKT1	S130	R134G	134	Missense	distal	4	no	16.169	16.332	EPSD;PhosphoSitePlus	COSMIC	7.780	Up-regulation
AGC_Akt_AKT1_ST	P84103	SRSF3	P31749	AKT1	S138	D132V	132	Missense	distal	-6	no	16.412	16.455	EPSD;PhosphoSitePlus	COSMIC	7.780	Up-regulation
AGC_Akt_AKT1_ST	P84103	SRSF3	P31749	AKT1	S138	R141W	141	Missense	distal	3	no	16.412	16.300	EPSD;PhosphoSitePlus	COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	P84103	SRSF3	P31749	AKT1	S138	R134K	134	Missense	distal	-4	no	16.412	16.398	EPSD;PhosphoSitePlus	COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	P84103	SRSF3	P31749	AKT1	S138	R134G	134	Missense	distal	-4	no	16.412	15.597	EPSD;PhosphoSitePlus	COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	P84103	SRSF3	P31749	AKT1	S140	R141W	141	Missense	proximal	1	no	16.590	16.297	EPSD;PhosphoSitePlus	COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	P84103	SRSF3	P31749	AKT1	S140	R134K	134	Missense	distal	-6	no	16.590	16.575	EPSD;PhosphoSitePlus	COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	P84103	SRSF3	P31749	AKT1	S140	R134G	134	Missense	distal	-6	no	16.590	16.476	EPSD;PhosphoSitePlus	COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	P84103	SRSF3	P31749	AKT1	S148	R141W	141	Missense	distal	-7	no	13.610	13.187	EPSD	COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	P84103	SRSF3	P31749	AKT1	S156	R163K	163	Missense	distal	7	no	15.818	15.810	EPSD	COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	P84103	SRSF3	P31749	AKT1	S158	R163K	163	Missense	distal	5	no	18.645	18.638	EPSD	COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	P84103	SRSF3	P31749	AKT1	S160	R163K	163	Missense	distal	3	no	18.378	18.397	EPSD	COSMIC	7.780	Up-regulation
AGC_Akt_AKT1_ST	Q13188	STK3	P31749	AKT1	S15	S18C	18	Missense	distal	3	no	10.241	10.064	EPSD	COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	Q13188	STK3	P31749	AKT1	S15	K10T	10	Missense	distal	-5	no	10.241	8.909	EPSD	COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	Q13188	STK3	P31749	AKT1	S15	E16D	16	Missense	proximal	1	no	10.241	10.124	EPSD	COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	Q13188	STK3	P31749	AKT1	T117	R112K	112	Missense	distal	-5	no	13.333	10.936	EPSD;PhosphoSitePlus	COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	Q13188	STK3	P31749	AKT1	T117	I110T	110	Missense	distal	-7	no	13.333	13.755	EPSD;PhosphoSitePlus	COSMIC	7.780	Up-regulation
AGC_Akt_AKT1_ST	Q13188	STK3	P31749	AKT1	T117	R114Q	114	Missense	distal	-3	no	13.333	6.122	EPSD;PhosphoSitePlus	COSMIC	7.780	Loss
AGC_Akt_AKT1_ST	Q13188	STK3	P31749	AKT1	T384	R390S	390	Missense	distal	6	no	10.753	10.754	PhosphoSitePlus;EPSD	COSMIC	7.780	Up-regulation
AGC_Akt_AKT1_ST	Q13188	STK3	P31749	AKT1	T384	T378A	378	Missense	distal	-6	no	10.753	10.667	PhosphoSitePlus;EPSD	COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	Q13188	STK3	P31749	AKT1	T384	V388I	388	Missense	distal	4	no	10.753	10.834	PhosphoSitePlus;EPSD	COSMIC	7.780	Up-regulation
AGC_Akt_AKT1_ST	Q92794	KAT6A	P31749	AKT1	T332	R337H	337	Missense	distal	5	no	9.379	9.305	EPSD	COSMIC;GDSC;CCLE	7.780	Down-regulation
AGC_Akt_AKT1_ST	Q92794	KAT6A	P31749	AKT1	T369	T369I	369	Missense	central	0	yes	17.379	0.000	PhosphoSitePlus	COSMIC	7.780	Loss
AGC_Akt_AKT1_ST	Q92794	KAT6A	P31749	AKT1	T369	L370V	370	Missense	proximal	1	no	17.379	17.279	PhosphoSitePlus	COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	Q92794	KAT6A	P31749	AKT1	T369	A375S	375	Missense	distal	6	no	17.379	17.461	PhosphoSitePlus	COSMIC	7.780	Up-regulation
AGC_Akt_AKT1_ST	Q92794	KAT6A	P31749	AKT1	S371	T369I	369	Missense	proximal	-2	no	11.150	9.975	EPSD	COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	Q92794	KAT6A	P31749	AKT1	S371	L370V	370	Missense	proximal	-1	no	11.150	11.143	EPSD	COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	Q92794	KAT6A	P31749	AKT1	S371	A375S	375	Missense	distal	4	no	11.150	11.025	EPSD	COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	Q92794	KAT6A	P31749	AKT1	S371	S378L	378	Missense	distal	7	no	11.150	11.083	EPSD	COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	Q92794	KAT6A	P31749	AKT1	S812	S816C	816	Missense	distal	4	no	8.450	8.795	EPSD	COSMIC	7.780	Up-regulation
AGC_Akt_AKT1_ST	Q92794	KAT6A	P31749	AKT1	S812	R807S	807	Missense	distal	-5	no	8.450	3.979	EPSD	COSMIC	7.780	Loss
AGC_Akt_AKT1_ST	Q92794	KAT6A	P31749	AKT1	S812	I811N	811	Missense	proximal	-1	no	8.450	8.481	EPSD	COSMIC	7.780	Up-regulation
AGC_Akt_AKT1_ST	Q92794	KAT6A	P31749	AKT1	S812	S818P	818	Missense	distal	6	no	8.450	8.356	EPSD	COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	Q92794	KAT6A	P31749	AKT1	S941	P946A	946	Missense	distal	5	no	11.309	11.311	EPSD	COSMIC	7.780	Up-regulation
AGC_Akt_AKT1_ST	Q92794	KAT6A	P31749	AKT1	S941	P936S	936	Missense	distal	-5	no	11.309	10.849	EPSD	COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	Q92794	KAT6A	P31749	AKT1	S941	R939T	939	Missense	proximal	-2	no	11.309	11.431	EPSD	COSMIC	7.780	Up-regulation
AGC_Akt_AKT1_ST	Q92794	KAT6A	P31749	AKT1	S974	P970S	970	Missense	distal	-4	no	11.254	11.990	EPSD	COSMIC	7.780	Up-regulation
AGC_Akt_AKT1_ST	Q92794	KAT6A	P31749	AKT1	S974	S974N	974	Missense	central	0	yes	11.254	0.000	EPSD	COSMIC	7.780	Loss
AGC_Akt_AKT1_ST	Q92794	KAT6A	P31749	AKT1	S985	E989K	989	Missense	distal	4	no	9.520	9.419	EPSD	COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	Q92794	KAT6A	P31749	AKT1	S987	E989K	989	Missense	proximal	2	no	10.278	10.483	EPSD	COSMIC	7.780	Up-regulation
AGC_Akt_AKT1_ST	Q92794	KAT6A	P31749	AKT1	S1001	R998L	998	Missense	distal	-3	no	11.664	4.670	EPSD	COSMIC;CCLE	7.780	Loss
AGC_Akt_AKT1_ST	Q92794	KAT6A	P31749	AKT1	S1001	R998W	998	Missense	distal	-3	no	11.664	2.724	EPSD	COSMIC	7.780	Loss
AGC_Akt_AKT1_ST	Q92794	KAT6A	P31749	AKT1	S1089	R1086L	1086	Missense	distal	-3	no	10.985	3.991	EPSD	COSMIC	7.780	Loss
AGC_Akt_AKT1_ST	Q92794	KAT6A	P31749	AKT1	S1090	R1086L	1086	Missense	distal	-4	no	13.066	11.857	EPSD	COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	Q92794	KAT6A	P31749	AKT1	S1104	R1102K	1102	Missense	proximal	-2	no	7.450	7.889	EPSD	COSMIC	7.780	Gain
AGC_Akt_AKT1_ST	Q92794	KAT6A	P31749	AKT1	S1136	R1131C	1131	Missense	distal	-5	no	8.489	4.412	EPSD	COSMIC	7.780	Loss
AGC_Akt_AKT1_ST	Q92794	KAT6A	P31749	AKT1	S1136	D1141E	1141	Missense	distal	5	no	8.489	8.531	EPSD	COSMIC	7.780	Up-regulation
AGC_Akt_AKT1_ST	Q9UKV3	ACIN1	P31749	AKT1	T9	T13N	13	Missense	distal	4	no	11.750	11.864	EPSD	COSMIC;GDSC;CCLE	7.780	Up-regulation
AGC_Akt_AKT1_ST	Q9UKV3	ACIN1	P31749	AKT1	T9	V16I	16	Missense	distal	7	no	11.750	11.707	EPSD	COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	Q9UKV3	ACIN1	P31749	AKT1	S10	T13N	13	Missense	distal	3	no	8.812	8.757	EPSD	COSMIC;GDSC;CCLE	7.780	Down-regulation
AGC_Akt_AKT1_ST	Q9UKV3	ACIN1	P31749	AKT1	S10	V16I	16	Missense	distal	6	no	8.812	8.762	EPSD	COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	Q9UKV3	ACIN1	P31749	AKT1	T13	T13N	13	Missense	central	0	yes	8.479	0.000	EPSD	COSMIC;GDSC;CCLE	7.780	Loss
AGC_Akt_AKT1_ST	Q9UKV3	ACIN1	P31749	AKT1	T13	V16I	16	Missense	distal	3	no	8.479	8.438	EPSD	COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	Q9UKV3	ACIN1	P31749	AKT1	S207	E212D	212	Missense	distal	5	no	10.916	10.873	EPSD	COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	Q9UKV3	ACIN1	P31749	AKT1	S207	E212K	212	Missense	distal	5	no	10.916	10.949	EPSD	COSMIC	7.780	Up-regulation
AGC_Akt_AKT1_ST	Q9UKV3	ACIN1	P31749	AKT1	S208	E212D	212	Missense	distal	4	no	7.840	7.986	EPSD	COSMIC	7.780	Up-regulation
AGC_Akt_AKT1_ST	Q9UKV3	ACIN1	P31749	AKT1	S208	E212K	212	Missense	distal	4	no	7.840	7.739	EPSD	COSMIC	7.780	Loss
AGC_Akt_AKT1_ST	Q9UKV3	ACIN1	P31749	AKT1	S229	V231I	231	Missense	proximal	2	no	11.478	11.360	EPSD	COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	Q9UKV3	ACIN1	P31749	AKT1	S229	S228A	228	Missense	proximal	-1	no	11.478	11.458	EPSD	COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	Q9UKV3	ACIN1	P31749	AKT1	S240	E241D	241	Missense	proximal	1	no	9.060	8.942	EPSD	COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	Q9UKV3	ACIN1	P31749	AKT1	T326	P324L	324	Missense	proximal	-2	no	10.447	10.415	EPSD	COSMIC;GDSC	7.780	Down-regulation
AGC_Akt_AKT1_ST	Q9UKV3	ACIN1	P31749	AKT1	S328	P324L	324	Missense	distal	-4	no	10.539	10.151	EPSD	COSMIC;GDSC	7.780	Down-regulation
AGC_Akt_AKT1_ST	Q9UKV3	ACIN1	P31749	AKT1	S377	E371K	371	Missense	distal	-6	no	8.358	8.424	EPSD	COSMIC	7.780	Up-regulation
AGC_Akt_AKT1_ST	Q9UKV3	ACIN1	P31749	AKT1	S386	P390L	390	Missense	distal	4	no	8.920	8.953	EPSD	COSMIC	7.780	Up-regulation
AGC_Akt_AKT1_ST	Q9UKV3	ACIN1	P31749	AKT1	S386	P389L	389	Missense	distal	3	no	8.920	8.904	EPSD	COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	Q9UKV3	ACIN1	P31749	AKT1	S388	P390L	390	Missense	proximal	2	no	10.362	10.153	EPSD	COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	Q9UKV3	ACIN1	P31749	AKT1	S388	P389L	389	Missense	proximal	1	no	10.362	10.616	EPSD	COSMIC	7.780	Up-regulation
AGC_Akt_AKT1_ST	Q9UKV3	ACIN1	P31749	AKT1	S400	V402L	402	Missense	proximal	2	no	8.911	8.903	EPSD	COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	Q9UKV3	ACIN1	P31749	AKT1	S400	R396W	396	Missense	distal	-4	no	8.911	7.361	EPSD	COSMIC	7.780	Loss
AGC_Akt_AKT1_ST	Q9UKV3	ACIN1	P31749	AKT1	T414	E411K	411	Missense	distal	-3	no	5.905	7.956	EPSD	COSMIC	7.780	Gain
AGC_Akt_AKT1_ST	Q9UKV3	ACIN1	P31749	AKT1	S424	P430L	430	Missense	distal	6	no	8.061	8.051	EPSD	COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	Q9UKV3	ACIN1	P31749	AKT1	S467	T461S	461	Missense	distal	-6	no	7.876	7.845	EPSD	COSMIC;GDSC;CCLE	7.780	Down-regulation
AGC_Akt_AKT1_ST	Q9UKV3	ACIN1	P31749	AKT1	S490	D485H	485	Missense	distal	-5	no	7.030	7.980	EPSD	COSMIC	7.780	Gain
AGC_Akt_AKT1_ST	Q9UKV3	ACIN1	P31749	AKT1	S561	R558I	558	Missense	distal	-3	no	10.184	3.103	EPSD	COSMIC	7.780	Loss
AGC_Akt_AKT1_ST	Q9UKV3	ACIN1	P31749	AKT1	S561	A560V	560	Missense	proximal	-1	no	10.184	10.169	EPSD	COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	Q9UKV3	ACIN1	P31749	AKT1	S561	P566R	566	Missense	distal	5	no	10.184	10.244	EPSD	COSMIC	7.780	Up-regulation
AGC_Akt_AKT1_ST	Q9UKV3	ACIN1	P31749	AKT1	S561	S561Y	561	Missense	central	0	yes	10.184	0.000	EPSD	COSMIC	7.780	Loss
AGC_Akt_AKT1_ST	Q9UKV3	ACIN1	P31749	AKT1	S561	R559C	559	Missense	proximal	-2	no	10.184	8.720	EPSD	COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	Q9UKV3	ACIN1	P31749	AKT1	S561	H562D	562	Missense	proximal	1	no	10.184	10.148	EPSD	COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	Q9UKV3	ACIN1	P31749	AKT1	S561	H562P	562	Missense	proximal	1	no	10.184	10.206	EPSD	COSMIC	7.780	Up-regulation
AGC_Akt_AKT1_ST	Q9UKV3	ACIN1	P31749	AKT1	T563	R558I	558	Missense	distal	-5	no	8.730	4.162	EPSD	COSMIC	7.780	Loss
AGC_Akt_AKT1_ST	Q9UKV3	ACIN1	P31749	AKT1	T563	A560V	560	Missense	distal	-3	no	8.730	8.168	EPSD	COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	Q9UKV3	ACIN1	P31749	AKT1	T563	P566R	566	Missense	distal	3	no	8.730	8.795	EPSD	COSMIC	7.780	Up-regulation
AGC_Akt_AKT1_ST	Q9UKV3	ACIN1	P31749	AKT1	T563	S561Y	561	Missense	proximal	-2	no	8.730	7.808	EPSD	COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	Q9UKV3	ACIN1	P31749	AKT1	T563	R559C	559	Missense	distal	-4	no	8.730	7.051	EPSD	COSMIC	7.780	Loss
AGC_Akt_AKT1_ST	Q9UKV3	ACIN1	P31749	AKT1	T563	H562D	562	Missense	proximal	-1	no	8.730	8.716	EPSD	COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	Q9UKV3	ACIN1	P31749	AKT1	T563	H562P	562	Missense	proximal	-1	no	8.730	8.735	EPSD	COSMIC	7.780	Up-regulation
AGC_Akt_AKT1_ST	Q9UKV3	ACIN1	P31749	AKT1	S583	S576L	576	Missense	distal	-7	no	12.629	12.395	EPSD	COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	Q9UKV3	ACIN1	P31749	AKT1	S583	S589L	589	Missense	distal	6	no	12.629	12.525	EPSD	COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	Q9UKV3	ACIN1	P31749	AKT1	S585	S591C	591	Missense	distal	6	no	10.277	10.074	EPSD	COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	Q9UKV3	ACIN1	P31749	AKT1	S585	S589L	589	Missense	distal	4	no	10.277	10.466	EPSD	COSMIC	7.780	Up-regulation
AGC_Akt_AKT1_ST	Q9UKV3	ACIN1	P31749	AKT1	S593	G600S	600	Missense	distal	7	no	13.530	13.604	EPSD	COSMIC	7.780	Up-regulation
AGC_Akt_AKT1_ST	Q9UKV3	ACIN1	P31749	AKT1	S593	G600V	600	Missense	distal	7	no	13.530	13.549	EPSD	COSMIC	7.780	Up-regulation
AGC_Akt_AKT1_ST	Q9UKV3	ACIN1	P31749	AKT1	S593	S591C	591	Missense	proximal	-2	no	13.530	11.878	EPSD	COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	Q9UKV3	ACIN1	P31749	AKT1	S593	S589L	589	Missense	distal	-4	no	13.530	12.406	EPSD	COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	Q9UKV3	ACIN1	P31749	AKT1	S595	G600S	600	Missense	distal	5	no	16.348	16.411	EPSD	COSMIC	7.780	Up-regulation
AGC_Akt_AKT1_ST	Q9UKV3	ACIN1	P31749	AKT1	S595	S601Y	601	Missense	distal	6	no	16.348	16.260	EPSD	COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	Q9UKV3	ACIN1	P31749	AKT1	S595	G600V	600	Missense	distal	5	no	16.348	16.351	EPSD	COSMIC	7.780	Up-regulation
AGC_Akt_AKT1_ST	Q9UKV3	ACIN1	P31749	AKT1	S595	R602H	602	Missense	distal	7	no	16.348	16.277	EPSD	COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	Q9UKV3	ACIN1	P31749	AKT1	S595	S591C	591	Missense	distal	-4	no	16.348	14.755	EPSD	COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	Q9UKV3	ACIN1	P31749	AKT1	S595	S589L	589	Missense	distal	-6	no	16.348	16.298	EPSD	COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	Q9UKV3	ACIN1	P31749	AKT1	S599	G600S	600	Missense	proximal	1	no	9.211	9.516	EPSD	COSMIC	7.780	Up-regulation
AGC_Akt_AKT1_ST	Q9UKV3	ACIN1	P31749	AKT1	S599	P606R	606	Missense	distal	7	no	9.211	9.277	EPSD	COSMIC	7.780	Up-regulation
AGC_Akt_AKT1_ST	Q9UKV3	ACIN1	P31749	AKT1	S599	S601Y	601	Missense	proximal	2	no	9.211	8.839	EPSD	COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	Q9UKV3	ACIN1	P31749	AKT1	S599	G600V	600	Missense	proximal	1	no	9.211	9.515	EPSD	COSMIC	7.780	Up-regulation
AGC_Akt_AKT1_ST	Q9UKV3	ACIN1	P31749	AKT1	S599	R602H	602	Missense	distal	3	no	9.211	9.128	EPSD	COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	Q9UKV3	ACIN1	P31749	AKT1	S599	S603C	603	Missense	distal	4	no	9.211	9.556	EPSD	COSMIC	7.780	Up-regulation
AGC_Akt_AKT1_ST	Q9UKV3	ACIN1	P31749	AKT1	S599	S603F	603	Missense	distal	4	no	9.211	9.407	EPSD	COSMIC	7.780	Up-regulation
AGC_Akt_AKT1_ST	Q9UKV3	ACIN1	P31749	AKT1	S605	G600S	600	Missense	distal	-5	no	10.344	9.939	EPSD	COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	Q9UKV3	ACIN1	P31749	AKT1	S605	P606R	606	Missense	proximal	1	no	10.344	10.644	EPSD	COSMIC	7.780	Up-regulation
AGC_Akt_AKT1_ST	Q9UKV3	ACIN1	P31749	AKT1	S605	S601Y	601	Missense	distal	-4	no	10.344	9.485	EPSD	COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	Q9UKV3	ACIN1	P31749	AKT1	S605	G600V	600	Missense	distal	-5	no	10.344	10.094	EPSD	COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	Q9UKV3	ACIN1	P31749	AKT1	S605	R602H	602	Missense	distal	-3	no	10.344	5.646	EPSD	COSMIC	7.780	Loss
AGC_Akt_AKT1_ST	Q9UKV3	ACIN1	P31749	AKT1	S605	R608Q	608	Missense	distal	3	no	10.344	10.288	EPSD	COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	Q9UKV3	ACIN1	P31749	AKT1	S605	S603C	603	Missense	proximal	-2	no	10.344	8.692	EPSD	COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	Q9UKV3	ACIN1	P31749	AKT1	S605	S603F	603	Missense	proximal	-2	no	10.344	9.478	EPSD	COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	Q9UKV3	ACIN1	P31749	AKT1	S609	P606R	606	Missense	distal	-3	no	6.661	13.301	EPSD	COSMIC	7.780	Gain
AGC_Akt_AKT1_ST	Q9UKV3	ACIN1	P31749	AKT1	S631	R624H	624	Missense	distal	-7	no	10.506	10.204	EPSD	COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	Q9UKV3	ACIN1	P31749	AKT1	S631	G630S	630	Missense	proximal	-1	no	10.506	10.535	EPSD	COSMIC	7.780	Up-regulation
AGC_Akt_AKT1_ST	Q9UKV3	ACIN1	P31749	AKT1	S631	R638K	638	Missense	distal	7	no	10.506	10.498	EPSD	COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	Q9UKV3	ACIN1	P31749	AKT1	S635	G630S	630	Missense	distal	-5	no	13.515	13.109	EPSD	COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	Q9UKV3	ACIN1	P31749	AKT1	S635	R638K	638	Missense	distal	3	no	13.515	13.534	EPSD	COSMIC	7.780	Up-regulation
AGC_Akt_AKT1_ST	Q9UKV3	ACIN1	P31749	AKT1	S637	R644H	644	Missense	distal	7	no	9.196	9.124	EPSD	COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	Q9UKV3	ACIN1	P31749	AKT1	S637	G630S	630	Missense	distal	-7	no	9.196	9.382	EPSD	COSMIC	7.780	Up-regulation
AGC_Akt_AKT1_ST	Q9UKV3	ACIN1	P31749	AKT1	S637	S643L	643	Missense	distal	6	no	9.196	9.092	EPSD	COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	Q9UKV3	ACIN1	P31749	AKT1	S637	R638K	638	Missense	proximal	1	no	9.196	9.119	EPSD	COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	Q9UKV3	ACIN1	P31749	AKT1	S643	R644H	644	Missense	proximal	1	no	16.166	15.844	EPSD	COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	Q9UKV3	ACIN1	P31749	AKT1	S643	S643L	643	Missense	central	0	yes	16.166	0.000	EPSD	COSMIC	7.780	Loss
AGC_Akt_AKT1_ST	Q9UKV3	ACIN1	P31749	AKT1	S643	R638K	638	Missense	distal	-5	no	16.166	13.769	EPSD	COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	Q9UKV3	ACIN1	P31749	AKT1	S645	R644H	644	Missense	proximal	-1	no	16.880	16.836	EPSD	COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	Q9UKV3	ACIN1	P31749	AKT1	S645	S643L	643	Missense	proximal	-2	no	16.880	16.023	EPSD	COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	Q9UKV3	ACIN1	P31749	AKT1	S645	R638K	638	Missense	distal	-7	no	16.880	16.867	EPSD	COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	Q9UKV3	ACIN1	P31749	AKT1	S647	R644H	644	Missense	distal	-3	no	16.700	12.001	EPSD	COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	Q9UKV3	ACIN1	P31749	AKT1	S647	S643L	643	Missense	distal	-4	no	16.700	15.576	EPSD	COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	Q9UKV3	ACIN1	P31749	AKT1	S649	R644H	644	Missense	distal	-5	no	15.202	12.108	EPSD	COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	Q9UKV3	ACIN1	P31749	AKT1	S649	S643L	643	Missense	distal	-6	no	15.202	15.152	EPSD	COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	Q9UKV3	ACIN1	P31749	AKT1	S665	S661L	661	Missense	distal	-4	no	11.178	10.054	EPSD	COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	Q9UKV3	ACIN1	P31749	AKT1	T699	R696K	696	Missense	distal	-3	no	12.101	7.580	EPSD	COSMIC	7.780	Loss
AGC_Akt_AKT1_ST	Q9UKV3	ACIN1	P31749	AKT1	S701	R696K	696	Missense	distal	-5	no	9.519	7.122	EPSD	COSMIC	7.780	Loss
AGC_Akt_AKT1_ST	Q9UKV3	ACIN1	P31749	AKT1	S710	S714T	714	Missense	distal	4	no	11.643	11.638	EPSD	COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	Q9UKV3	ACIN1	P31749	AKT1	S815	P817L	817	Missense	proximal	2	no	8.218	8.009	EPSD	COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	Q9UKV3	ACIN1	P31749	AKT1	T855	R849H	849	Missense	distal	-6	no	8.452	8.333	EPSD	COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	Q9UKV3	ACIN1	P31749	AKT1	S983	G988R	988	Missense	distal	5	no	12.353	12.423	EPSD	COSMIC	7.780	Up-regulation
AGC_Akt_AKT1_ST	Q9UKV3	ACIN1	P31749	AKT1	S983	V989L	989	Missense	distal	6	no	12.353	12.363	EPSD	COSMIC	7.780	Up-regulation
AGC_Akt_AKT1_ST	Q9UKV3	ACIN1	P31749	AKT1	T1159	R1160Q	1160	Missense	proximal	1	no	11.318	11.023	EPSD	COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	Q9UKV3	ACIN1	P31749	AKT1	T1159	R1156Q	1156	Missense	distal	-3	no	11.318	4.106	EPSD	COSMIC;GDSC;CCLE	7.780	Loss
AGC_Akt_AKT1_ST	Q9UKV3	ACIN1	P31749	AKT1	T1159	R1158L	1158	Missense	proximal	-1	no	11.318	11.279	EPSD	COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	Q9UKV3	ACIN1	P31749	AKT1	T1159	R1158Q	1158	Missense	proximal	-1	no	11.318	11.285	EPSD	COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	Q9UKV3	ACIN1	P31749	AKT1	S1161	R1160Q	1160	Missense	proximal	-1	no	14.927	14.895	EPSD	COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	Q9UKV3	ACIN1	P31749	AKT1	S1161	R1167Q	1167	Missense	distal	6	no	14.927	14.856	EPSD	COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	Q9UKV3	ACIN1	P31749	AKT1	S1161	R1156Q	1156	Missense	distal	-5	no	14.927	10.699	EPSD	COSMIC;GDSC;CCLE	7.780	Down-regulation
AGC_Akt_AKT1_ST	Q9UKV3	ACIN1	P31749	AKT1	S1161	R1158L	1158	Missense	distal	-3	no	14.927	7.933	EPSD	COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	Q9UKV3	ACIN1	P31749	AKT1	S1161	R1158Q	1158	Missense	distal	-3	no	14.927	7.716	EPSD	COSMIC	7.780	Loss
AGC_Akt_AKT1_ST	Q9UKV3	ACIN1	P31749	AKT1	S1176	R1177Q	1177	Missense	proximal	1	no	8.383	8.088	EPSD	COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	Q9UKV3	ACIN1	P31749	AKT1	S1176	R1181L	1181	Missense	distal	5	no	8.383	8.309	EPSD	COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	Q9UKV3	ACIN1	P31749	AKT1	S1176	K1169N	1169	Missense	distal	-7	no	8.383	8.226	EPSD	COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	Q9UKV3	ACIN1	P31749	AKT1	S1176	R1171L	1171	Missense	distal	-5	no	8.383	4.257	EPSD	COSMIC	7.780	Loss
AGC_Akt_AKT1_ST	Q9UKV3	ACIN1	P31749	AKT1	S1176	R1171S	1171	Missense	distal	-5	no	8.383	3.913	EPSD	COSMIC	7.780	Loss
AGC_Akt_AKT1_ST	Q9UKV3	ACIN1	P31749	AKT1	S1176	R1183W	1183	Missense	distal	7	no	8.383	8.285	EPSD	COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	Q9UKV3	ACIN1	P31749	AKT1	S1178	R1177Q	1177	Missense	proximal	-1	no	12.207	12.174	EPSD	COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	Q9UKV3	ACIN1	P31749	AKT1	S1178	R1181L	1181	Missense	distal	3	no	12.207	12.125	EPSD	COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	Q9UKV3	ACIN1	P31749	AKT1	S1178	R1171L	1171	Missense	distal	-7	no	12.207	11.917	EPSD	COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	Q9UKV3	ACIN1	P31749	AKT1	S1178	R1171S	1171	Missense	distal	-7	no	12.207	12.151	EPSD	COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	Q9UKV3	ACIN1	P31749	AKT1	S1178	R1183W	1183	Missense	distal	5	no	12.207	12.112	EPSD	COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	Q9UKV3	ACIN1	P31749	AKT1	S1180	R1177Q	1177	Missense	distal	-3	no	16.215	9.004	PhosphoSitePlus	COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	Q9UKV3	ACIN1	P31749	AKT1	S1180	R1181L	1181	Missense	proximal	1	no	16.215	16.169	PhosphoSitePlus	COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	Q9UKV3	ACIN1	P31749	AKT1	S1180	R1183W	1183	Missense	distal	3	no	16.215	16.103	PhosphoSitePlus	COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	Q9UKV3	ACIN1	P31749	AKT1	S1284	R1281W	1281	Missense	distal	-3	no	14.748	5.807	EPSD	COSMIC	7.780	Loss
AGC_Akt_AKT1_ST	Q9UKV3	ACIN1	P31749	AKT1	S1284	R1281Q	1281	Missense	distal	-3	no	14.748	7.537	EPSD	COSMIC;GDSC;CCLE	7.780	Loss
AGC_Akt_AKT1_ST	Q9UKV3	ACIN1	P31749	AKT1	S1284	S1284N	1284	Missense	central	0	yes	14.748	0.000	EPSD	COSMIC	7.780	Loss
AGC_Akt_AKT1_ST	Q9UKV3	ACIN1	P31749	AKT1	S1284	R1277Q	1277	Missense	distal	-7	no	14.748	14.553	EPSD	COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	Q9UKV3	ACIN1	P31749	AKT1	S1325	S1331G	1331	Missense	distal	6	no	9.002	8.897	EPSD	COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	Q9UKV3	ACIN1	P31749	AKT1	S1325	H1324Q	1324	Missense	proximal	-1	no	9.002	9.015	EPSD	COSMIC	7.780	Up-regulation
AGC_Akt_AKT1_ST	Q9UKV3	ACIN1	P31749	AKT1	S1325	R1318C	1318	Missense	distal	-7	no	9.002	8.523	EPSD	COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	Q9UKV3	ACIN1	P31749	AKT1	S1325	R1330W	1330	Missense	distal	5	no	9.002	8.908	EPSD	COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	Q9UKV3	ACIN1	P31749	AKT1	S1325	S1329N	1329	Missense	distal	4	no	9.002	9.112	EPSD	COSMIC	7.780	Up-regulation
AGC_Akt_AKT1_ST	Q9UKV3	ACIN1	P31749	AKT1	S1325	S1327I	1327	Missense	proximal	2	no	9.002	8.346	EPSD	COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	Q9UKV3	ACIN1	P31749	AKT1	S1325	R1328C	1328	Missense	distal	3	no	9.002	8.842	EPSD	COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	Q9UKV3	ACIN1	P31749	AKT1	S1327	S1331G	1331	Missense	distal	4	no	13.043	13.217	EPSD	COSMIC	7.780	Up-regulation
AGC_Akt_AKT1_ST	Q9UKV3	ACIN1	P31749	AKT1	S1327	H1324Q	1324	Missense	distal	-3	no	13.043	10.531	EPSD	COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	Q9UKV3	ACIN1	P31749	AKT1	S1327	R1330W	1330	Missense	distal	3	no	13.043	12.931	EPSD	COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	Q9UKV3	ACIN1	P31749	AKT1	S1327	S1329N	1329	Missense	proximal	2	no	13.043	12.774	EPSD	COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	Q9UKV3	ACIN1	P31749	AKT1	S1327	S1327I	1327	Missense	central	0	yes	13.043	0.000	EPSD	COSMIC	7.780	Loss
AGC_Akt_AKT1_ST	Q9UKV3	ACIN1	P31749	AKT1	S1327	R1328C	1328	Missense	proximal	1	no	13.043	12.515	EPSD	COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	Q9UKV3	ACIN1	P31749	AKT1	S1329	S1331G	1331	Missense	proximal	2	no	16.581	16.249	EPSD	COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	Q9UKV3	ACIN1	P31749	AKT1	S1329	H1324Q	1324	Missense	distal	-5	no	16.581	15.448	EPSD	COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	Q9UKV3	ACIN1	P31749	AKT1	S1329	R1330W	1330	Missense	proximal	1	no	16.581	16.288	EPSD	COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	Q9UKV3	ACIN1	P31749	AKT1	S1329	S1329N	1329	Missense	central	0	yes	16.581	0.000	EPSD	COSMIC	7.780	Loss
AGC_Akt_AKT1_ST	Q9UKV3	ACIN1	P31749	AKT1	S1329	S1327I	1327	Missense	proximal	-2	no	16.581	15.340	EPSD	COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	Q9UKV3	ACIN1	P31749	AKT1	S1329	R1328C	1328	Missense	proximal	-1	no	16.581	16.510	EPSD	COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	Q9UKV3	ACIN1	P31749	AKT1	S1331	S1331G	1331	Missense	central	0	yes	19.055	0.000	EPSD	COSMIC	7.780	Loss
AGC_Akt_AKT1_ST	Q9UKV3	ACIN1	P31749	AKT1	S1331	H1324Q	1324	Missense	distal	-7	no	19.055	19.162	EPSD	COSMIC	7.780	Up-regulation
AGC_Akt_AKT1_ST	Q9UKV3	ACIN1	P31749	AKT1	S1331	R1330W	1330	Missense	proximal	-1	no	19.055	18.994	EPSD	COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	Q9UKV3	ACIN1	P31749	AKT1	S1331	S1329N	1329	Missense	proximal	-2	no	19.055	18.369	EPSD	COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	Q9UKV3	ACIN1	P31749	AKT1	S1331	R1337L	1337	Missense	distal	6	no	19.055	18.953	EPSD	COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	Q9UKV3	ACIN1	P31749	AKT1	S1331	S1327I	1327	Missense	distal	-4	no	19.055	17.673	EPSD	COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	Q9UKV3	ACIN1	P31749	AKT1	S1331	R1328C	1328	Missense	distal	-3	no	19.055	12.882	EPSD	COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	Q07352	ZFP36L1	P31749	AKT1	S54	L57Q	57	Missense	distal	3	no	11.489	11.514	EPSD	COSMIC	7.780	Up-regulation
AGC_Akt_AKT1_ST	Q07352	ZFP36L1	P31749	AKT1	S54	P50L	50	Missense	distal	-4	no	11.489	11.101	EPSD	COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	Q07352	ZFP36L1	P31749	AKT1	T56	L57Q	57	Missense	proximal	1	no	10.539	10.290	EPSD	COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	Q07352	ZFP36L1	P31749	AKT1	T56	P50L	50	Missense	distal	-6	no	10.539	10.553	EPSD	COSMIC	7.780	Up-regulation
AGC_Akt_AKT1_ST	Q07352	ZFP36L1	P31749	AKT1	S90	S92L	92	Missense	proximal	2	no	14.321	13.775	EPSD	COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	Q07352	ZFP36L1	P31749	AKT1	S92	L98P	98	Missense	distal	6	no	16.289	16.299	PhosphoSitePlus;EPSD	COSMIC	7.780	Up-regulation
AGC_Akt_AKT1_ST	Q07352	ZFP36L1	P31749	AKT1	S92	S92L	92	Missense	central	0	yes	16.289	0.000	PhosphoSitePlus;EPSD	COSMIC	7.780	Loss
AGC_Akt_AKT1_ST	Q07352	ZFP36L1	P31749	AKT1	T148	T155M	155	Missense	distal	7	no	10.497	10.428	EPSD	COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	Q07352	ZFP36L1	P31749	AKT1	S192	R195C	195	Missense	distal	3	no	10.035	9.874	EPSD	COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	Q07352	ZFP36L1	P31749	AKT1	S192	A188T	188	Missense	distal	-4	no	10.035	10.813	EPSD	COSMIC	7.780	Up-regulation
AGC_Akt_AKT1_ST	Q07352	ZFP36L1	P31749	AKT1	S192	L191F	191	Missense	proximal	-1	no	10.035	10.029	EPSD	COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	Q07352	ZFP36L1	P31749	AKT1	S203	A205V	205	Missense	proximal	2	no	8.916	8.754	EPSD;PhosphoSitePlus	COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	Q07352	ZFP36L1	P31749	AKT1	S203	H200R	200	Missense	distal	-3	no	8.916	13.615	EPSD;PhosphoSitePlus	COSMIC	7.780	Up-regulation
AGC_Akt_AKT1_ST	Q07352	ZFP36L1	P31749	AKT1	S283	D290E	290	Missense	distal	7	no	10.331	10.374	EPSD	COSMIC	7.780	Up-regulation
AGC_Akt_AKT1_ST	Q07352	ZFP36L1	P31749	AKT1	S316	S311C	311	Missense	distal	-5	no	9.838	10.232	EPSD	COSMIC;GDSC	7.780	Up-regulation
AGC_Akt_AKT1_ST	Q07352	ZFP36L1	P31749	AKT1	S318	S311C	311	Missense	distal	-7	no	9.296	8.873	EPSD	COSMIC;GDSC	7.780	Down-regulation
AGC_Akt_AKT1_ST	Q07352	ZFP36L1	P31749	AKT1	S331	R326H	326	Missense	distal	-5	no	9.959	6.864	EPSD	COSMIC	7.780	Loss
AGC_Akt_AKT1_ST	Q9Y3C5	RNF11	P31749	AKT1	T9	G2K	2	Missense	distal	-7	no	8.105	8.334	EPSD	COSMIC	7.780	Up-regulation
AGC_Akt_AKT1_ST	Q9Y3C5	RNF11	P31749	AKT1	T135	C139Y	139	Missense	distal	4	no	11.853	11.644	PhosphoSitePlus	COSMIC;GDSC;CCLE	7.780	Down-regulation
AGC_Akt_AKT1_ST	Q14315	FLNC	P31749	AKT1	T423	Q418H	418	Missense	distal	-5	no	9.759	10.892	EPSD	COSMIC	7.780	Up-regulation
AGC_Akt_AKT1_ST	Q14315	FLNC	P31749	AKT1	S729	R727L	727	Missense	proximal	-2	no	8.740	8.071	EPSD	COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	Q14315	FLNC	P31749	AKT1	S729	R727C	727	Missense	proximal	-2	no	8.740	7.276	EPSD	COSMIC	7.780	Loss
AGC_Akt_AKT1_ST	Q14315	FLNC	P31749	AKT1	S729	G722S	722	Missense	distal	-7	no	8.740	8.926	EPSD	COSMIC;GDSC;CCLE	7.780	Up-regulation
AGC_Akt_AKT1_ST	Q14315	FLNC	P31749	AKT1	S729	G724S	724	Missense	distal	-5	no	8.740	8.334	EPSD	COSMIC;GDSC;CCLE	7.780	Down-regulation
AGC_Akt_AKT1_ST	Q14315	FLNC	P31749	AKT1	S729	V731M	731	Missense	proximal	2	no	8.740	8.861	EPSD	COSMIC	7.780	Up-regulation
AGC_Akt_AKT1_ST	Q14315	FLNC	P31749	AKT1	S1005	P1012S	1012	Missense	distal	7	no	10.467	10.525	EPSD	COSMIC	7.780	Up-regulation
AGC_Akt_AKT1_ST	Q14315	FLNC	P31749	AKT1	S1005	D1000E	1000	Missense	distal	-5	no	10.467	10.418	EPSD	COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	Q14315	FLNC	P31749	AKT1	S1005	V1001L	1001	Missense	distal	-4	no	10.467	10.437	EPSD	COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	Q14315	FLNC	P31749	AKT1	S1007	P1012S	1012	Missense	distal	5	no	9.815	9.868	EPSD	COSMIC	7.780	Up-regulation
AGC_Akt_AKT1_ST	Q14315	FLNC	P31749	AKT1	S1007	D1000E	1000	Missense	distal	-7	no	9.815	10.036	EPSD	COSMIC	7.780	Up-regulation
AGC_Akt_AKT1_ST	Q14315	FLNC	P31749	AKT1	S1007	V1001L	1001	Missense	distal	-6	no	9.815	9.840	EPSD	COSMIC	7.780	Up-regulation
AGC_Akt_AKT1_ST	Q14315	FLNC	P31749	AKT1	S1893	G1890R	1890	Missense	distal	-3	no	4.636	11.392	EPSD	COSMIC	7.780	Gain
AGC_Akt_AKT1_ST	Q14315	FLNC	P31749	AKT1	S1927	G1924R	1924	Missense	distal	-3	no	2.865	9.621	EPSD	COSMIC	7.780	Gain
AGC_Akt_AKT1_ST	Q14315	FLNC	P31749	AKT1	S1985	E1988K	1988	Missense	distal	3	no	10.952	10.995	EPSD	COSMIC	7.780	Up-regulation
AGC_Akt_AKT1_ST	Q14315	FLNC	P31749	AKT1	S1985	P1984S	1984	Missense	proximal	-1	no	10.952	10.981	EPSD	COSMIC	7.780	Up-regulation
AGC_Akt_AKT1_ST	Q14315	FLNC	P31749	AKT1	S1985	P1990T	1990	Missense	distal	5	no	10.952	11.005	EPSD	COSMIC	7.780	Up-regulation
AGC_Akt_AKT1_ST	Q14315	FLNC	P31749	AKT1	S1985	P1990S	1990	Missense	distal	5	no	10.952	11.005	EPSD	COSMIC	7.780	Up-regulation
AGC_Akt_AKT1_ST	Q14315	FLNC	P31749	AKT1	S1985	A1979T	1979	Missense	distal	-6	no	10.952	11.038	EPSD	COSMIC	7.780	Up-regulation
AGC_Akt_AKT1_ST	Q14315	FLNC	P31749	AKT1	S1985	E1989K	1989	Missense	distal	4	no	10.952	10.851	EPSD	COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	Q14315	FLNC	P31749	AKT1	S1985	A1979V	1979	Missense	distal	-6	no	10.952	10.931	EPSD	COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	Q14315	FLNC	P31749	AKT1	T2179	S2181I	2181	Missense	proximal	2	no	12.798	12.142	EPSD	COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	Q14315	FLNC	P31749	AKT1	T2179	R2176H	2176	Missense	distal	-3	no	12.798	8.099	EPSD	COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	Q14315	FLNC	P31749	AKT1	T2179	R2173C	2173	Missense	distal	-6	no	12.798	12.618	EPSD	COSMIC;GDSC;CCLE	7.780	Down-regulation
AGC_Akt_AKT1_ST	Q14315	FLNC	P31749	AKT1	T2179	T2177N	2177	Missense	proximal	-2	no	12.798	12.179	EPSD	COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	Q14315	FLNC	P31749	AKT1	S2181	S2181I	2181	Missense	central	0	yes	11.571	0.000	EPSD	COSMIC	7.780	Loss
AGC_Akt_AKT1_ST	Q14315	FLNC	P31749	AKT1	S2181	R2187H	2187	Missense	distal	6	no	11.571	11.451	EPSD	COSMIC;GDSC;CCLE	7.780	Down-regulation
AGC_Akt_AKT1_ST	Q14315	FLNC	P31749	AKT1	S2181	R2176H	2176	Missense	distal	-5	no	11.571	8.476	EPSD	COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	Q14315	FLNC	P31749	AKT1	S2181	T2177N	2177	Missense	distal	-4	no	11.571	10.948	EPSD	COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	Q14315	FLNC	P31749	AKT1	S2233	R2230L	2230	Missense	distal	-3	no	15.302	8.308	PhosphoSitePlus	COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	Q14315	FLNC	P31749	AKT1	S2233	R2239L	2239	Missense	distal	6	no	15.302	15.199	PhosphoSitePlus	COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	Q14315	FLNC	P31749	AKT1	T2412	S2415L	2415	Missense	distal	3	no	12.147	12.049	EPSD	COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	Q14315	FLNC	P31749	AKT1	T2412	R2410W	2410	Missense	proximal	-2	no	12.147	10.892	EPSD	COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	Q14315	FLNC	P31749	AKT1	T2412	R2409H	2409	Missense	distal	-3	no	12.147	7.448	EPSD	COSMIC	7.780	Loss
AGC_Akt_AKT1_ST	Q14315	FLNC	P31749	AKT1	T2414	S2415L	2415	Missense	proximal	1	no	9.293	9.391	EPSD	COSMIC	7.780	Up-regulation
AGC_Akt_AKT1_ST	Q14315	FLNC	P31749	AKT1	T2414	R2410W	2410	Missense	distal	-4	no	9.293	7.743	EPSD	COSMIC	7.780	Loss
AGC_Akt_AKT1_ST	Q14315	FLNC	P31749	AKT1	T2414	R2409H	2409	Missense	distal	-5	no	9.293	6.198	EPSD	COSMIC	7.780	Loss
AGC_Akt_AKT1_ST	Q14315	FLNC	P31749	AKT1	T2414	G2420R	2420	Missense	distal	6	no	9.293	9.397	EPSD	COSMIC	7.780	Up-regulation
AGC_Akt_AKT1_ST	Q14315	FLNC	P31749	AKT1	T2446	P2447H	2447	Missense	proximal	1	no	8.924	8.902	EPSD	COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	Q14315	FLNC	P31749	AKT1	T2446	E2453K	2453	Missense	distal	7	no	8.924	8.958	EPSD	COSMIC	7.780	Up-regulation
AGC_Akt_AKT1_ST	Q14315	FLNC	P31749	AKT1	T2446	R2443W	2443	Missense	distal	-3	no	8.924	-0.016	EPSD	COSMIC	7.780	Loss
AGC_Akt_AKT1_ST	Q14315	FLNC	P31749	AKT1	T2446	P2447L	2447	Missense	proximal	1	no	8.924	9.178	EPSD	COSMIC;GDSC;CCLE	7.780	Up-regulation
AGC_Akt_AKT1_ST	Q14315	FLNC	P31749	AKT1	T2446	I2440T	2440	Missense	distal	-6	no	8.924	9.075	EPSD	COSMIC	7.780	Up-regulation
AGC_Akt_AKT1_ST	Q14315	FLNC	P31749	AKT1	S2448	P2447H	2447	Missense	proximal	-1	no	10.470	10.465	EPSD	COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	Q14315	FLNC	P31749	AKT1	S2448	E2453K	2453	Missense	distal	5	no	10.470	10.504	EPSD	COSMIC	7.780	Up-regulation
AGC_Akt_AKT1_ST	Q14315	FLNC	P31749	AKT1	S2448	R2443W	2443	Missense	distal	-5	no	10.470	4.950	EPSD	COSMIC	7.780	Loss
AGC_Akt_AKT1_ST	Q14315	FLNC	P31749	AKT1	S2448	P2447L	2447	Missense	proximal	-1	no	10.470	10.471	EPSD	COSMIC;GDSC;CCLE	7.780	Up-regulation
AGC_Akt_AKT1_ST	Q14315	FLNC	P31749	AKT1	S2448	Y2455C	2455	Missense	distal	7	no	10.470	10.390	EPSD	COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	Q14315	FLNC	P31749	AKT1	S2624	S2619T	2619	Missense	distal	-5	no	12.121	12.861	EPSD	COSMIC	7.780	Up-regulation
AGC_Akt_AKT1_ST	Q14315	FLNC	P31749	AKT1	S2624	Y2625F	2625	Missense	proximal	1	no	12.121	12.146	EPSD	COSMIC	7.780	Up-regulation
AGC_Akt_AKT1_ST	Q14315	FLNC	P31749	AKT1	S2626	S2619T	2619	Missense	distal	-7	no	8.485	8.535	EPSD	COSMIC	7.780	Up-regulation
AGC_Akt_AKT1_ST	Q14315	FLNC	P31749	AKT1	S2626	Y2625F	2625	Missense	proximal	-1	no	8.485	8.476	EPSD	COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	Q14315	FLNC	P31749	AKT1	S2646	F2649S	2649	Missense	distal	3	no	8.723	8.821	EPSD	COSMIC;CCLE	7.780	Up-regulation
AGC_Akt_AKT1_ST	Q15027	ACAP1	P31749	AKT1	S371	L368R	368	Missense	distal	-3	no	4.075	11.069	EPSD	COSMIC	7.780	Gain
AGC_Akt_AKT1_ST	Q15027	ACAP1	P31749	AKT1	S459	T461P	461	Missense	proximal	2	no	7.976	7.714	EPSD	COSMIC	7.780	Loss
AGC_Akt_AKT1_ST	Q15027	ACAP1	P31749	AKT1	S720	D714E	714	Missense	distal	-6	no	10.787	10.859	EPSD	COSMIC	7.780	Up-regulation
AGC_Akt_AKT1_ST	Q15027	ACAP1	P31749	AKT1	S720	D718G	718	Missense	proximal	-2	no	10.787	11.486	EPSD	COSMIC	7.780	Up-regulation
AGC_Akt_AKT1_ST	Q15027	ACAP1	P31749	AKT1	S724	D718G	718	Missense	distal	-6	no	7.816	7.855	EPSD	COSMIC	7.780	Up-regulation
AGC_Akt_AKT1_ST	Q15027	ACAP1	P31749	AKT1	S731	R732S	732	Missense	proximal	1	no	9.397	9.252	EPSD	COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	Q15027	ACAP1	P31749	AKT1	S731	R732C	732	Missense	proximal	1	no	9.397	8.869	EPSD	COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	Q13107	USP4	P31749	AKT1	S244	P251L	251	Missense	distal	7	no	10.240	10.232	EPSD	COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	Q13107	USP4	P31749	AKT1	S248	P251L	251	Missense	distal	3	no	8.144	8.128	EPSD	COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	Q13107	USP4	P31749	AKT1	S248	S253F	253	Missense	distal	5	no	8.144	8.072	EPSD	COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	Q13107	USP4	P31749	AKT1	S445	H452N	452	Missense	distal	7	no	14.403	14.432	PhosphoSitePlus	COSMIC	7.780	Up-regulation
AGC_Akt_AKT1_ST	Q13107	USP4	P31749	AKT1	S445	S445Y	445	Missense	central	0	yes	14.403	0.000	PhosphoSitePlus	COSMIC	7.780	Loss
AGC_Akt_AKT1_ST	Q13107	USP4	P31749	AKT1	S445	R442M	442	Missense	distal	-3	no	14.403	6.898	PhosphoSitePlus	COSMIC	7.780	Loss
AGC_Akt_AKT1_ST	Q13107	USP4	P31749	AKT1	S592	S595F	595	Missense	distal	3	no	9.018	8.919	EPSD	COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	Q13107	USP4	P31749	AKT1	S592	A599V	599	Missense	distal	7	no	9.018	9.013	EPSD	COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	Q13107	USP4	P31749	AKT1	S593	S595F	595	Missense	proximal	2	no	13.949	13.372	EPSD	COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	Q13107	USP4	P31749	AKT1	S593	A599V	599	Missense	distal	6	no	13.949	13.918	EPSD	COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	Q13107	USP4	P31749	AKT1	S595	S595F	595	Missense	central	0	yes	8.917	0.000	EPSD	COSMIC	7.780	Loss
AGC_Akt_AKT1_ST	Q13107	USP4	P31749	AKT1	S595	A599V	599	Missense	distal	4	no	8.917	8.973	EPSD	COSMIC	7.780	Up-regulation
AGC_Akt_AKT1_ST	Q13107	USP4	P31749	AKT1	T775	I782T	782	Missense	distal	7	no	8.183	8.291	EPSD	COSMIC	7.780	Up-regulation
AGC_Akt_AKT1_ST	Q13107	USP4	P31749	AKT1	S829	S829F	829	Missense	central	0	yes	7.863	0.000	EPSD	COSMIC	7.780	Loss
AGC_Akt_AKT1_ST	Q13107	USP4	P31749	AKT1	S829	V822A	822	Missense	distal	-7	no	7.863	7.991	EPSD	COSMIC;GDSC;CCLE	7.780	Up-regulation
AGC_Akt_AKT1_ST	Q13107	USP4	P31749	AKT1	S829	R827H	827	Missense	proximal	-2	no	7.863	7.002	EPSD	COSMIC	7.780	Loss
AGC_Akt_AKT1_ST	Q13107	USP4	P31749	AKT1	T943	S938F	938	Missense	distal	-5	no	7.090	8.038	EPSD	COSMIC	7.780	Gain
AGC_Akt_AKT1_ST	Q13107	USP4	P31749	AKT1	S947	R944Q	944	Missense	distal	-3	no	12.260	5.049	EPSD	COSMIC	7.780	Loss
AGC_Akt_AKT1_ST	Q13107	USP4	P31749	AKT1	S947	G951R	951	Missense	distal	4	no	12.260	12.098	EPSD	COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	P03372	ESR1	P31749	AKT1	S154	A148E	148	Missense	distal	-6	no	11.303	11.311	EPSD	COSMIC	7.780	Up-regulation
AGC_Akt_AKT1_ST	P03372	ESR1	P31749	AKT1	S154	R151K	151	Missense	distal	-3	no	11.303	6.782	EPSD	COSMIC	7.780	Loss
AGC_Akt_AKT1_ST	P03372	ESR1	P31749	AKT1	S154	P147Q	147	Missense	distal	-7	no	11.303	11.358	EPSD	COSMIC	7.780	Up-regulation
AGC_Akt_AKT1_ST	P03372	ESR1	P31749	AKT1	S154	R158C	158	Missense	distal	4	no	11.303	11.637	EPSD	COSMIC	7.780	Up-regulation
AGC_Akt_AKT1_ST	P03372	ESR1	P31749	AKT1	S154	Q159L	159	Missense	distal	5	no	11.303	11.279	EPSD	COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	P03372	ESR1	P31749	AKT1	S154	R157Q	157	Missense	distal	3	no	11.303	11.246	EPSD	COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	P03372	ESR1	P31749	AKT1	S154	N156T	156	Missense	proximal	2	no	11.303	11.497	EPSD	COSMIC	7.780	Up-regulation
AGC_Akt_AKT1_ST	P03372	ESR1	P31749	AKT1	S154	G160D	160	Missense	distal	6	no	11.303	11.258	EPSD	COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	P03372	ESR1	P31749	AKT1	S154	P152S	152	Missense	proximal	-2	no	11.303	12.127	EPSD	COSMIC	7.780	Up-regulation
AGC_Akt_AKT1_ST	P03372	ESR1	P31749	AKT1	S154	P152L	152	Missense	proximal	-2	no	11.303	11.270	EPSD	COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	P03372	ESR1	P31749	AKT1	S167	G172R	172	Missense	distal	5	no	16.129	16.200	PhosphoSitePlus;EPSD	COSMIC	7.780	Up-regulation
AGC_Akt_AKT1_ST	P03372	ESR1	P31749	AKT1	S167	M174I	174	Missense	distal	7	no	16.129	16.091	PhosphoSitePlus;EPSD	COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	P03372	ESR1	P31749	AKT1	S167	D170Y	170	Missense	distal	3	no	16.129	16.173	PhosphoSitePlus;EPSD	COSMIC	7.780	Up-regulation
AGC_Akt_AKT1_ST	P03372	ESR1	P31749	AKT1	S167	G160D	160	Missense	distal	-7	no	16.129	15.944	PhosphoSitePlus;EPSD	COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	P03372	ESR1	P31749	AKT1	S236	R241G	241	Missense	distal	5	no	13.602	13.531	EPSD	COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	P03372	ESR1	P31749	AKT1	S236	R241W	241	Missense	distal	5	no	13.602	13.507	EPSD	COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	P03372	ESR1	P31749	AKT1	S236	R233G	233	Missense	distal	-3	no	13.602	6.846	EPSD	COSMIC	7.780	Loss
AGC_Akt_AKT1_ST	P03372	ESR1	P31749	AKT1	S236	C237Y	237	Missense	proximal	1	no	13.602	13.978	EPSD	COSMIC	7.780	Up-regulation
AGC_Akt_AKT1_ST	P03372	ESR1	P31749	AKT1	S236	Q238H	238	Missense	proximal	2	no	13.602	13.358	EPSD	COSMIC;CCLE	7.780	Down-regulation
AGC_Akt_AKT1_ST	P03372	ESR1	P31749	AKT1	S236	R243L	243	Missense	distal	7	no	13.602	13.528	EPSD	COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	P03372	ESR1	P31749	AKT1	S305	K303R	303	Missense	proximal	-2	no	12.276	11.836	EPSD;PhosphoSitePlus	COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	P03372	ESR1	P31749	AKT1	S305	K299R	299	Missense	distal	-6	no	12.276	12.290	EPSD;PhosphoSitePlus	COSMIC	7.780	Up-regulation
AGC_Akt_AKT1_ST	P03372	ESR1	P31749	AKT1	S305	N304S	304	Missense	proximal	-1	no	12.276	12.294	EPSD;PhosphoSitePlus	COSMIC	7.780	Up-regulation
AGC_Akt_AKT1_ST	P03372	ESR1	P31749	AKT1	S305	R300C	300	Missense	distal	-5	no	12.276	8.199	EPSD;PhosphoSitePlus	COSMIC;CCLE	7.780	Down-regulation
AGC_Akt_AKT1_ST	P03372	ESR1	P31749	AKT1	S305	A307P	307	Missense	proximal	2	no	12.276	12.315	EPSD;PhosphoSitePlus	COSMIC	7.780	Up-regulation
AGC_Akt_AKT1_ST	P03372	ESR1	P31749	AKT1	S305	N304H	304	Missense	proximal	-1	no	12.276	12.259	EPSD;PhosphoSitePlus	COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	P03372	ESR1	P31749	AKT1	S341	S338R	338	Missense	distal	-3	no	3.301	11.077	EPSD	COSMIC	7.780	Gain
AGC_Akt_AKT1_ST	Q12778	FOXO1	P31749	AKT1	S22	R21L	21	Missense	proximal	-1	no	10.495	10.456	EPSD	COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	Q12778	FOXO1	P31749	AKT1	S22	T24M	24	Missense	proximal	2	no	10.495	10.153	EPSD	COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	Q12778	FOXO1	P31749	AKT1	S22	E15Q	15	Missense	distal	-7	no	10.495	10.506	EPSD	COSMIC	7.780	Up-regulation
AGC_Akt_AKT1_ST	Q12778	FOXO1	P31749	AKT1	S22	R21S	21	Missense	proximal	-1	no	10.495	10.484	EPSD	COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	Q12778	FOXO1	P31749	AKT1	S22	P28S	28	Missense	distal	6	no	10.495	10.588	EPSD	COSMIC	7.780	Up-regulation
AGC_Akt_AKT1_ST	Q12778	FOXO1	P31749	AKT1	S22	P26L	26	Missense	distal	4	no	10.495	10.527	EPSD	COSMIC	7.780	Up-regulation
AGC_Akt_AKT1_ST	Q12778	FOXO1	P31749	AKT1	S22	C23W	23	Missense	proximal	1	no	10.495	10.730	EPSD	COSMIC	7.780	Up-regulation
AGC_Akt_AKT1_ST	Q12778	FOXO1	P31749	AKT1	S22	P26A	26	Missense	distal	4	no	10.495	10.463	EPSD	COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	Q12778	FOXO1	P31749	AKT1	S22	R19P	19	Missense	distal	-3	no	10.495	3.855	EPSD	COSMIC	7.780	Loss
AGC_Akt_AKT1_ST	Q12778	FOXO1	P31749	AKT1	S22	P16T	16	Missense	distal	-6	no	10.495	10.589	EPSD	COSMIC	7.780	Up-regulation
AGC_Akt_AKT1_ST	Q12778	FOXO1	P31749	AKT1	S22	W25R	25	Missense	distal	3	no	10.495	10.606	EPSD	COSMIC	7.780	Up-regulation
AGC_Akt_AKT1_ST	Q12778	FOXO1	P31749	AKT1	T24	R21L	21	Missense	distal	-3	no	14.694	7.700	EPSD;PhosphoSitePlus	COSMIC	7.780	Loss
AGC_Akt_AKT1_ST	Q12778	FOXO1	P31749	AKT1	T24	T24M	24	Missense	central	0	yes	14.694	0.000	EPSD;PhosphoSitePlus	COSMIC	7.780	Loss
AGC_Akt_AKT1_ST	Q12778	FOXO1	P31749	AKT1	T24	R21S	21	Missense	distal	-3	no	14.694	6.918	EPSD;PhosphoSitePlus	COSMIC	7.780	Loss
AGC_Akt_AKT1_ST	Q12778	FOXO1	P31749	AKT1	T24	P28S	28	Missense	distal	4	no	14.694	14.538	EPSD;PhosphoSitePlus	COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	Q12778	FOXO1	P31749	AKT1	T24	P26L	26	Missense	proximal	2	no	14.694	14.485	EPSD;PhosphoSitePlus	COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	Q12778	FOXO1	P31749	AKT1	T24	C23W	23	Missense	proximal	-1	no	14.694	14.704	EPSD;PhosphoSitePlus	COSMIC	7.780	Up-regulation
AGC_Akt_AKT1_ST	Q12778	FOXO1	P31749	AKT1	T24	P26A	26	Missense	proximal	2	no	14.694	14.654	EPSD;PhosphoSitePlus	COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	Q12778	FOXO1	P31749	AKT1	T24	R19P	19	Missense	distal	-5	no	14.694	10.684	EPSD;PhosphoSitePlus	COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	Q12778	FOXO1	P31749	AKT1	T24	W25R	25	Missense	proximal	1	no	14.694	14.987	EPSD;PhosphoSitePlus	COSMIC	7.780	Up-regulation
AGC_Akt_AKT1_ST	Q12778	FOXO1	P31749	AKT1	S206	S203R	203	Missense	distal	-3	no	2.216	9.992	EPSD	COSMIC	7.780	Gain
AGC_Akt_AKT1_ST	Q12778	FOXO1	P31749	AKT1	S276	Q278L	278	Missense	proximal	2	no	8.877	8.621	EPSD	COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	Q12778	FOXO1	P31749	AKT1	S276	L277F	277	Missense	proximal	1	no	8.877	8.796	EPSD	COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	Q12778	FOXO1	P31749	AKT1	T317	P315F	315	Missense	proximal	-2	no	10.948	10.906	EPSD	COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	Q12778	FOXO1	P31749	AKT1	T317	W310C	310	Missense	distal	-7	no	10.948	10.893	EPSD	COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	Q12778	FOXO1	P31749	AKT1	S319	P315F	315	Missense	distal	-4	no	17.079	16.647	PhosphoSitePlus;EPSD	COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	Q12778	FOXO1	P31749	AKT1	T648	S644I	644	Missense	distal	-4	no	8.077	6.695	EPSD	COSMIC	7.780	Loss
AGC_Akt_AKT1_ST	Q12778	FOXO1	P31749	AKT1	S651	S644I	644	Missense	distal	-7	no	9.253	8.881	EPSD	COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	P24941	CDK2	P31749	AKT1	T39	K34N	34	Missense	distal	-5	no	11.312	9.225	PhosphoSitePlus	COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	P24941	CDK2	P31749	AKT1	T39	P45L	45	Missense	distal	6	no	11.312	11.302	PhosphoSitePlus	COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	P24941	CDK2	P31749	AKT1	T39	E42K	42	Missense	distal	3	no	11.312	11.356	PhosphoSitePlus	COSMIC	7.780	Up-regulation
AGC_Akt_AKT1_ST	P24941	CDK2	P31749	AKT1	T41	K34N	34	Missense	distal	-7	no	8.353	8.196	EPSD	COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	P24941	CDK2	P31749	AKT1	T41	P45L	45	Missense	distal	4	no	8.353	8.386	EPSD	COSMIC	7.780	Up-regulation
AGC_Akt_AKT1_ST	P24941	CDK2	P31749	AKT1	T41	E42K	42	Missense	proximal	1	no	8.353	8.517	EPSD	COSMIC	7.780	Up-regulation
AGC_Akt_AKT1_ST	P24941	CDK2	P31749	AKT1	S53	K56Q	56	Missense	distal	3	no	10.981	10.906	EPSD	COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	P24941	CDK2	P31749	AKT1	S53	N59S	59	Missense	distal	6	no	10.981	11.048	EPSD	COSMIC	7.780	Up-regulation
AGC_Akt_AKT1_ST	P24941	CDK2	P31749	AKT1	T160	P155S	155	Missense	distal	-5	no	10.875	10.415	EPSD	COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	P24941	CDK2	P31749	AKT1	T160	V164L	164	Missense	distal	4	no	10.875	10.883	EPSD	COSMIC	7.780	Up-regulation
AGC_Akt_AKT1_ST	P55316	FOXG1	P31749	AKT1	S277	T270M	270	Missense	distal	-7	no	13.906	13.640	EPSD	COSMIC;GDSC;CCLE	7.780	Down-regulation
AGC_Akt_AKT1_ST	P55316	FOXG1	P31749	AKT1	S277	T270K	270	Missense	distal	-7	no	13.906	13.898	EPSD	COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	P55316	FOXG1	P31749	AKT1	S277	T279N	279	Missense	proximal	2	no	13.906	13.712	EPSD	COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	P55316	FOXG1	P31749	AKT1	S277	R281W	281	Missense	distal	4	no	13.906	14.153	EPSD	COSMIC	7.780	Up-regulation
AGC_Akt_AKT1_ST	P55316	FOXG1	P31749	AKT1	T278	T279N	279	Missense	proximal	1	no	12.506	12.225	EPSD	COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	P55316	FOXG1	P31749	AKT1	T278	R281W	281	Missense	distal	3	no	12.506	12.395	EPSD	COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	P55316	FOXG1	P31749	AKT1	T279	F286L	286	Missense	distal	7	no	15.575	15.582	PhosphoSitePlus	COSMIC	7.780	Up-regulation
AGC_Akt_AKT1_ST	P55316	FOXG1	P31749	AKT1	T279	T279N	279	Missense	central	0	yes	15.575	0.000	PhosphoSitePlus	COSMIC	7.780	Loss
AGC_Akt_AKT1_ST	P55316	FOXG1	P31749	AKT1	T279	R281W	281	Missense	proximal	2	no	15.575	15.119	PhosphoSitePlus	COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	P55316	FOXG1	P31749	AKT1	S280	F286L	286	Missense	distal	6	no	9.778	9.794	EPSD	COSMIC	7.780	Up-regulation
AGC_Akt_AKT1_ST	P55316	FOXG1	P31749	AKT1	S280	T279N	279	Missense	proximal	-1	no	9.778	9.754	EPSD	COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	P55316	FOXG1	P31749	AKT1	S280	R281W	281	Missense	proximal	1	no	9.778	9.486	EPSD	COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	P15056	BRAF	P31749	AKT1	T244	F247L	247	Missense	distal	3	no	8.175	8.176	EPSD	COSMIC	7.780	Up-regulation
AGC_Akt_AKT1_ST	P15056	BRAF	P31749	AKT1	T244	V238I	238	Missense	distal	-6	no	8.175	8.130	EPSD	COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	P15056	BRAF	P31749	AKT1	T244	F243S	243	Missense	proximal	-1	no	8.175	8.209	EPSD	COSMIC	7.780	Up-regulation
AGC_Akt_AKT1_ST	P15056	BRAF	P31749	AKT1	S363	R360Q	360	Missense	distal	-3	no	12.988	5.776	EPSD	COSMIC	7.780	Loss
AGC_Akt_AKT1_ST	P15056	BRAF	P31749	AKT1	S363	S365L	365	Missense	proximal	2	no	12.988	12.442	EPSD	COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	P15056	BRAF	P31749	AKT1	S363	R362L	362	Missense	proximal	-1	no	12.988	12.949	EPSD	COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	P15056	BRAF	P31749	AKT1	S363	Q356K	356	Missense	distal	-7	no	12.988	13.169	EPSD	COSMIC	7.780	Up-regulation
AGC_Akt_AKT1_ST	P15056	BRAF	P31749	AKT1	S363	F357S	357	Missense	distal	-6	no	12.988	13.062	EPSD	COSMIC	7.780	Up-regulation
AGC_Akt_AKT1_ST	P15056	BRAF	P31749	AKT1	S365	R360Q	360	Missense	distal	-5	no	16.893	12.665	PhosphoSitePlus;EPSD	COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	P15056	BRAF	P31749	AKT1	S365	S365L	365	Missense	central	0	yes	16.893	0.000	PhosphoSitePlus;EPSD	COSMIC	7.780	Loss
AGC_Akt_AKT1_ST	P15056	BRAF	P31749	AKT1	S365	R362L	362	Missense	distal	-3	no	16.893	9.899	PhosphoSitePlus;EPSD	COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	P15056	BRAF	P31749	AKT1	S394	G387V	387	Missense	distal	-7	no	9.120	9.029	EPSD	COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	P15056	BRAF	P31749	AKT1	S394	A400S	400	Missense	distal	6	no	9.120	9.202	EPSD	COSMIC	7.780	Up-regulation
AGC_Akt_AKT1_ST	P15056	BRAF	P31749	AKT1	S429	P422A	422	Missense	distal	-7	no	17.215	17.260	EPSD;PhosphoSitePlus	COSMIC	7.780	Up-regulation
AGC_Akt_AKT1_ST	P15056	BRAF	P31749	AKT1	S429	S428L	428	Missense	proximal	-1	no	17.215	17.187	EPSD;PhosphoSitePlus	COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	P15056	BRAF	P31749	AKT1	S429	R424L	424	Missense	distal	-5	no	17.215	13.089	EPSD;PhosphoSitePlus	COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	P15056	BRAF	P31749	AKT1	S430	S428L	428	Missense	proximal	-2	no	8.153	7.297	EPSD	COSMIC	7.780	Loss
AGC_Akt_AKT1_ST	P15056	BRAF	P31749	AKT1	S430	R424L	424	Missense	distal	-6	no	8.153	8.068	EPSD	COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	P15056	BRAF	P31749	AKT1	S431	S428L	428	Missense	distal	-3	no	9.847	10.630	EPSD	COSMIC	7.780	Up-regulation
AGC_Akt_AKT1_ST	P15056	BRAF	P31749	AKT1	S431	R424L	424	Missense	distal	-7	no	9.847	9.558	EPSD	COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	P15056	BRAF	P31749	AKT1	T440	S447N	447	Missense	distal	7	no	13.648	13.613	EPSD	COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	P15056	BRAF	P31749	AKT1	T440	R443I	443	Missense	distal	3	no	13.648	13.534	EPSD	COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	P15056	BRAF	P31749	AKT1	T440	R443T	443	Missense	distal	3	no	13.648	13.664	EPSD	COSMIC	7.780	Up-regulation
AGC_Akt_AKT1_ST	P15056	BRAF	P31749	AKT1	T440	K439T	439	Missense	proximal	-1	no	13.648	13.647	EPSD	COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	P15056	BRAF	P31749	AKT1	T440	G442S	442	Missense	proximal	2	no	13.648	13.980	EPSD	COSMIC	7.780	Up-regulation
AGC_Akt_AKT1_ST	P15056	BRAF	P31749	AKT1	T440	T440P	440	Missense	central	0	yes	13.648	0.000	EPSD	COSMIC	7.780	Loss
AGC_Akt_AKT1_ST	P15056	BRAF	P31749	AKT1	T440	L441V	441	Missense	proximal	1	no	13.648	13.548	EPSD	COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	P15056	BRAF	P31749	AKT1	T440	K439Q	439	Missense	proximal	-1	no	13.648	13.620	EPSD	COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	P15056	BRAF	P31749	AKT1	T440	S447C	447	Missense	distal	7	no	13.648	13.526	EPSD	COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	P15056	BRAF	P31749	AKT1	T440	G442D	442	Missense	proximal	2	no	13.648	13.381	EPSD	COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	P15056	BRAF	P31749	AKT1	T440	T440I	440	Missense	central	0	yes	13.648	0.000	EPSD	COSMIC	7.780	Loss
AGC_Akt_AKT1_ST	P15056	BRAF	P31749	AKT1	S446	S447N	447	Missense	proximal	1	no	11.248	11.160	EPSD	COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	P15056	BRAF	P31749	AKT1	S446	P453H	453	Missense	distal	7	no	11.248	11.243	EPSD	COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	P15056	BRAF	P31749	AKT1	S446	P453T	453	Missense	distal	7	no	11.248	11.317	EPSD	COSMIC	7.780	Up-regulation
AGC_Akt_AKT1_ST	P15056	BRAF	P31749	AKT1	S446	R443I	443	Missense	distal	-3	no	11.248	4.168	EPSD	COSMIC	7.780	Loss
AGC_Akt_AKT1_ST	P15056	BRAF	P31749	AKT1	S446	W450L	450	Missense	distal	4	no	11.248	11.179	EPSD	COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	P15056	BRAF	P31749	AKT1	S446	R443T	443	Missense	distal	-3	no	11.248	4.227	EPSD	COSMIC	7.780	Loss
AGC_Akt_AKT1_ST	P15056	BRAF	P31749	AKT1	S446	K439T	439	Missense	distal	-7	no	11.248	11.256	EPSD	COSMIC	7.780	Up-regulation
AGC_Akt_AKT1_ST	P15056	BRAF	P31749	AKT1	S446	G442S	442	Missense	distal	-4	no	11.248	11.978	EPSD	COSMIC	7.780	Up-regulation
AGC_Akt_AKT1_ST	P15056	BRAF	P31749	AKT1	S446	T440P	440	Missense	distal	-6	no	11.248	11.154	EPSD	COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	P15056	BRAF	P31749	AKT1	S446	L441V	441	Missense	distal	-5	no	11.248	11.060	EPSD	COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	P15056	BRAF	P31749	AKT1	S446	K439Q	439	Missense	distal	-7	no	11.248	11.067	EPSD	COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	P15056	BRAF	P31749	AKT1	S446	S447C	447	Missense	proximal	1	no	11.248	10.865	EPSD	COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	P15056	BRAF	P31749	AKT1	S446	D449E	449	Missense	distal	3	no	11.248	11.319	EPSD	COSMIC	7.780	Up-regulation
AGC_Akt_AKT1_ST	P15056	BRAF	P31749	AKT1	S446	G442D	442	Missense	distal	-4	no	11.248	10.690	EPSD	COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	P15056	BRAF	P31749	AKT1	S446	T440I	440	Missense	distal	-6	no	11.248	11.097	EPSD	COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	P15056	BRAF	P31749	AKT1	S446	W450R	450	Missense	distal	4	no	11.248	11.001	EPSD	COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	P15056	BRAF	P31749	AKT1	S446	D449Y	449	Missense	distal	3	no	11.248	11.292	EPSD	COSMIC	7.780	Up-regulation
AGC_Akt_AKT1_ST	P15056	BRAF	P31749	AKT1	S447	S447N	447	Missense	central	0	yes	9.898	0.000	EPSD	COSMIC	7.780	Loss
AGC_Akt_AKT1_ST	P15056	BRAF	P31749	AKT1	S447	P453H	453	Missense	distal	6	no	9.898	9.871	EPSD	COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	P15056	BRAF	P31749	AKT1	S447	P453T	453	Missense	distal	6	no	9.898	10.012	EPSD	COSMIC	7.780	Up-regulation
AGC_Akt_AKT1_ST	P15056	BRAF	P31749	AKT1	S447	R443I	443	Missense	distal	-4	no	9.898	8.431	EPSD	COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	P15056	BRAF	P31749	AKT1	S447	W450L	450	Missense	distal	3	no	9.898	9.929	EPSD	COSMIC	7.780	Up-regulation
AGC_Akt_AKT1_ST	P15056	BRAF	P31749	AKT1	S447	R443T	443	Missense	distal	-4	no	9.898	9.868	EPSD	COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	P15056	BRAF	P31749	AKT1	S447	G442S	442	Missense	distal	-5	no	9.898	9.492	EPSD	COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	P15056	BRAF	P31749	AKT1	S447	T440P	440	Missense	distal	-7	no	9.898	9.654	EPSD	COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	P15056	BRAF	P31749	AKT1	S447	D454N	454	Missense	distal	7	no	9.898	9.940	EPSD	COSMIC	7.780	Up-regulation
AGC_Akt_AKT1_ST	P15056	BRAF	P31749	AKT1	S447	L441V	441	Missense	distal	-6	no	9.898	9.873	EPSD	COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	P15056	BRAF	P31749	AKT1	S447	S447C	447	Missense	central	0	yes	9.898	0.000	EPSD	COSMIC	7.780	Loss
AGC_Akt_AKT1_ST	P15056	BRAF	P31749	AKT1	S447	D449E	449	Missense	proximal	2	no	9.898	10.308	EPSD	COSMIC	7.780	Up-regulation
AGC_Akt_AKT1_ST	P15056	BRAF	P31749	AKT1	S447	G442D	442	Missense	distal	-5	no	9.898	9.917	EPSD	COSMIC	7.780	Up-regulation
AGC_Akt_AKT1_ST	P15056	BRAF	P31749	AKT1	S447	T440I	440	Missense	distal	-7	no	9.898	9.476	EPSD	COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	P15056	BRAF	P31749	AKT1	S447	W450R	450	Missense	distal	3	no	9.898	10.010	EPSD	COSMIC	7.780	Up-regulation
AGC_Akt_AKT1_ST	P15056	BRAF	P31749	AKT1	S447	D449Y	449	Missense	proximal	2	no	9.898	10.125	EPSD	COSMIC	7.780	Up-regulation
AGC_Akt_AKT1_ST	P15056	BRAF	P31749	AKT1	S465	G469X	469	Missense	distal	4	no	11.227	11.232	EPSD	COSMIC	7.780	Up-regulation
AGC_Akt_AKT1_ST	P15056	BRAF	P31749	AKT1	S465	G469S	469	Missense	distal	4	no	11.227	11.053	EPSD	COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	P15056	BRAF	P31749	AKT1	S465	Y472S	472	Missense	distal	7	no	11.227	11.269	EPSD	COSMIC	7.780	Up-regulation
AGC_Akt_AKT1_ST	P15056	BRAF	P31749	AKT1	S465	Y472C	472	Missense	distal	7	no	11.227	11.147	EPSD	COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	P15056	BRAF	P31749	AKT1	S465	S467F	467	Missense	proximal	2	no	11.227	10.649	EPSD	COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	P15056	BRAF	P31749	AKT1	S465	V459L	459	Missense	distal	-6	no	11.227	11.252	EPSD	COSMIC	7.780	Up-regulation
AGC_Akt_AKT1_ST	P15056	BRAF	P31749	AKT1	S465	G464R	464	Missense	proximal	-1	no	11.227	11.267	EPSD	COSMIC	7.780	Up-regulation
AGC_Akt_AKT1_ST	P15056	BRAF	P31749	AKT1	S465	G469L	469	Missense	distal	4	no	11.227	11.241	EPSD	COSMIC	7.780	Up-regulation
AGC_Akt_AKT1_ST	P15056	BRAF	P31749	AKT1	S465	F468S	468	Missense	distal	3	no	11.227	11.325	EPSD	COSMIC	7.780	Up-regulation
AGC_Akt_AKT1_ST	P15056	BRAF	P31749	AKT1	S465	S465F	465	Missense	central	0	yes	11.227	0.000	EPSD	COSMIC	7.780	Loss
AGC_Akt_AKT1_ST	P15056	BRAF	P31749	AKT1	S465	V471A	471	Missense	distal	6	no	11.227	11.258	EPSD	COSMIC	7.780	Up-regulation
AGC_Akt_AKT1_ST	P15056	BRAF	P31749	AKT1	S465	R462I	462	Missense	distal	-3	no	11.227	4.146	EPSD	COSMIC	7.780	Loss
AGC_Akt_AKT1_ST	P15056	BRAF	P31749	AKT1	S465	T470I	470	Missense	distal	5	no	11.227	11.130	EPSD	COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	P15056	BRAF	P31749	AKT1	S465	I463N	463	Missense	proximal	-2	no	11.227	11.782	EPSD	COSMIC	7.780	Up-regulation
AGC_Akt_AKT1_ST	P15056	BRAF	P31749	AKT1	S465	G460R	460	Missense	distal	-5	no	11.227	15.291	EPSD	COSMIC	7.780	Up-regulation
AGC_Akt_AKT1_ST	P15056	BRAF	P31749	AKT1	S465	I463S	463	Missense	proximal	-2	no	11.227	12.468	EPSD	COSMIC	7.780	Up-regulation
AGC_Akt_AKT1_ST	P15056	BRAF	P31749	AKT1	S467	G469X	469	Missense	proximal	2	no	9.345	9.226	EPSD	COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	P15056	BRAF	P31749	AKT1	S467	G469S	469	Missense	proximal	2	no	9.345	9.677	EPSD	COSMIC	7.780	Up-regulation
AGC_Akt_AKT1_ST	P15056	BRAF	P31749	AKT1	S467	Y472S	472	Missense	distal	5	no	9.345	9.388	EPSD	COSMIC	7.780	Up-regulation
AGC_Akt_AKT1_ST	P15056	BRAF	P31749	AKT1	S467	Y472C	472	Missense	distal	5	no	9.345	9.269	EPSD	COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	P15056	BRAF	P31749	AKT1	S467	S467F	467	Missense	central	0	yes	9.345	0.000	EPSD	COSMIC	7.780	Loss
AGC_Akt_AKT1_ST	P15056	BRAF	P31749	AKT1	S467	G464R	464	Missense	distal	-3	no	9.345	16.101	EPSD	COSMIC	7.780	Up-regulation
AGC_Akt_AKT1_ST	P15056	BRAF	P31749	AKT1	S467	G469L	469	Missense	proximal	2	no	9.345	9.131	EPSD	COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	P15056	BRAF	P31749	AKT1	S467	F468S	468	Missense	proximal	1	no	9.345	9.327	EPSD	COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	P15056	BRAF	P31749	AKT1	S467	S465F	465	Missense	proximal	-2	no	9.345	8.478	EPSD	COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	P15056	BRAF	P31749	AKT1	S467	V471A	471	Missense	distal	4	no	9.345	9.289	EPSD	COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	P15056	BRAF	P31749	AKT1	S467	R462I	462	Missense	distal	-5	no	9.345	4.777	EPSD	COSMIC	7.780	Loss
AGC_Akt_AKT1_ST	P15056	BRAF	P31749	AKT1	S467	T470I	470	Missense	distal	3	no	9.345	9.215	EPSD	COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	P15056	BRAF	P31749	AKT1	S467	I463N	463	Missense	distal	-4	no	9.345	10.159	EPSD	COSMIC	7.780	Up-regulation
AGC_Akt_AKT1_ST	P15056	BRAF	P31749	AKT1	S467	G460R	460	Missense	distal	-7	no	9.345	9.587	EPSD	COSMIC	7.780	Up-regulation
AGC_Akt_AKT1_ST	P15056	BRAF	P31749	AKT1	S467	F468L	468	Missense	proximal	1	no	9.345	9.426	EPSD	COSMIC	7.780	Up-regulation
AGC_Akt_AKT1_ST	P15056	BRAF	P31749	AKT1	S467	I463S	463	Missense	distal	-4	no	9.345	10.726	EPSD	COSMIC	7.780	Up-regulation
AGC_Akt_AKT1_ST	P15056	BRAF	P31749	AKT1	S579	L577S	577	Missense	proximal	-2	no	7.333	8.190	EPSD	COSMIC	7.780	Gain
AGC_Akt_AKT1_ST	P15056	BRAF	P31749	AKT1	S602	L597R	597	Missense	distal	-5	no	3.667	7.794	EPSD	COSMIC;GDSC;CCLE	7.780	Gain
AGC_Akt_AKT1_ST	P15056	BRAF	P31749	AKT1	S602	T599R	599	Missense	distal	-3	no	3.667	10.689	EPSD	COSMIC	7.780	Gain
AGC_Akt_AKT1_ST	P15056	BRAF	P31749	AKT1	S607	W604R	604	Missense	distal	-3	no	3.521	12.461	EPSD	COSMIC	7.780	Gain
AGC_Akt_AKT1_ST	P15056	BRAF	P31749	AKT1	S614	Q609R	609	Missense	distal	-5	no	3.732	7.960	EPSD	COSMIC	7.780	Gain
AGC_Akt_AKT1_ST	P15056	BRAF	P31749	AKT1	S729	S732F	732	Missense	distal	3	no	11.274	11.176	EPSD	COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	P15056	BRAF	P31749	AKT1	S729	A728D	728	Missense	proximal	-1	no	11.274	11.247	EPSD	COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	P15056	BRAF	P31749	AKT1	S729	S727T	727	Missense	proximal	-2	no	11.274	11.207	EPSD	COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	P15056	BRAF	P31749	AKT1	S729	H725Q	725	Missense	distal	-4	no	11.274	11.712	EPSD	COSMIC	7.780	Up-regulation
AGC_Akt_AKT1_ST	Q9Y2V2	CARHSP1	P31749	AKT1	S17	G19R	19	Missense	proximal	2	no	8.770	8.930	EPSD	COSMIC	7.780	Up-regulation
AGC_Akt_AKT1_ST	Q9Y2V2	CARHSP1	P31749	AKT1	S30	R35W	35	Missense	distal	5	no	15.777	15.682	EPSD	COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	Q9Y2V2	CARHSP1	P31749	AKT1	S30	R29C	29	Missense	proximal	-1	no	15.777	15.706	EPSD	COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	Q9Y2V2	CARHSP1	P31749	AKT1	S30	P33S	33	Missense	distal	3	no	15.777	15.858	EPSD	COSMIC	7.780	Up-regulation
AGC_Akt_AKT1_ST	Q9Y2V2	CARHSP1	P31749	AKT1	S32	V39A	39	Missense	distal	7	no	15.393	15.397	EPSD	COSMIC	7.780	Up-regulation
AGC_Akt_AKT1_ST	Q9Y2V2	CARHSP1	P31749	AKT1	S32	R35W	35	Missense	distal	3	no	15.393	15.281	EPSD	COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	Q9Y2V2	CARHSP1	P31749	AKT1	S32	R29C	29	Missense	distal	-3	no	15.393	9.219	EPSD	COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	Q9Y2V2	CARHSP1	P31749	AKT1	S32	P33S	33	Missense	proximal	1	no	15.393	15.548	EPSD	COSMIC	7.780	Up-regulation
AGC_Akt_AKT1_ST	Q9Y2V2	CARHSP1	P31749	AKT1	T50	R46H	46	Missense	distal	-4	no	13.027	11.968	EPSD	COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	Q9Y2V2	CARHSP1	P31749	AKT1	S52	R46H	46	Missense	distal	-6	no	17.128	17.009	PhosphoSitePlus	COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	Q9Y2V2	CARHSP1	P31749	AKT1	T139	I145M	145	Missense	distal	6	no	8.510	8.575	EPSD	COSMIC	7.780	Up-regulation
AGC_Akt_AKT1_ST	Q9Y2V2	CARHSP1	P31749	AKT1	S141	I145M	145	Missense	distal	4	no	8.201	8.103	EPSD	COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	O14745	SLC9A3R1	P31749	AKT1	S269	K266R	266	Missense	distal	-3	no	7.395	11.915	EPSD	COSMIC	7.780	Gain
AGC_Akt_AKT1_ST	O14745	SLC9A3R1	P31749	AKT1	S290	L285M	285	Missense	distal	-5	no	11.028	10.632	EPSD	COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	O14745	SLC9A3R1	P31749	AKT1	S290	S294G	294	Missense	distal	4	no	11.028	11.201	EPSD	COSMIC	7.780	Up-regulation
AGC_Akt_AKT1_ST	O14745	SLC9A3R1	P31749	AKT1	S290	E296K	296	Missense	distal	6	no	11.028	11.097	EPSD	COSMIC	7.780	Up-regulation
AGC_Akt_AKT1_ST	O14745	SLC9A3R1	P31749	AKT1	S340	A343D	343	Missense	distal	3	no	10.058	10.004	EPSD	COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	O14745	SLC9A3R1	P31749	AKT1	S340	D347E	347	Missense	distal	7	no	10.058	10.101	EPSD	COSMIC	7.780	Up-regulation
AGC_Akt_AKT1_ST	P53365	ARFIP2	P31749	AKT1	T11	A9T	9	Missense	proximal	-2	no	7.557	7.943	EPSD	COSMIC	7.780	Gain
AGC_Akt_AKT1_ST	P53365	ARFIP2	P31749	AKT1	S72	S74N	74	Missense	proximal	2	no	12.451	12.182	EPSD	COSMIC;GDSC;CCLE	7.780	Down-regulation
AGC_Akt_AKT1_ST	P53365	ARFIP2	P31749	AKT1	S72	G68D	68	Missense	distal	-4	no	12.451	11.892	EPSD	COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	P53365	ARFIP2	P31749	AKT1	S72	S74R	74	Missense	proximal	2	no	12.451	12.279	EPSD	COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	P53365	ARFIP2	P31749	AKT1	S72	T75S	75	Missense	distal	3	no	12.451	12.452	EPSD	COSMIC	7.780	Up-regulation
AGC_Akt_AKT1_ST	P53365	ARFIP2	P31749	AKT1	S74	S74N	74	Missense	central	0	yes	9.738	0.000	EPSD	COSMIC;GDSC;CCLE	7.780	Loss
AGC_Akt_AKT1_ST	P53365	ARFIP2	P31749	AKT1	S74	G68D	68	Missense	distal	-6	no	9.738	9.699	EPSD	COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	P53365	ARFIP2	P31749	AKT1	S74	S74R	74	Missense	central	0	yes	9.738	0.000	EPSD	COSMIC	7.780	Loss
AGC_Akt_AKT1_ST	P53365	ARFIP2	P31749	AKT1	S74	P80S	80	Missense	distal	6	no	9.738	9.832	EPSD	COSMIC	7.780	Up-regulation
AGC_Akt_AKT1_ST	P53365	ARFIP2	P31749	AKT1	S74	T75S	75	Missense	proximal	1	no	9.738	9.545	EPSD	COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	P53365	ARFIP2	P31749	AKT1	S78	S74R	74	Missense	distal	-4	no	7.724	7.809	EPSD	COSMIC	7.780	Gain
AGC_Akt_AKT1_ST	P53365	ARFIP2	P31749	AKT1	S78	P80S	80	Missense	proximal	2	no	7.724	8.060	EPSD	COSMIC	7.780	Gain
AGC_Akt_AKT1_ST	P53365	ARFIP2	P31749	AKT1	S260	E259Q	259	Missense	proximal	-1	no	14.754	14.746	PhosphoSitePlus	COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	P53365	ARFIP2	P31749	AKT1	S260	T254M	254	Missense	distal	-6	no	14.754	14.661	PhosphoSitePlus	COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	Q9P0N9	TBC1D7	P31749	AKT1	T39	R36C	36	Missense	distal	-3	no	9.062	2.889	EPSD	COSMIC	7.780	Loss
AGC_Akt_AKT1_ST	Q9P0N9	TBC1D7	P31749	AKT1	T39	R36S	36	Missense	distal	-3	no	9.062	1.286	EPSD	COSMIC;GDSC;CCLE	7.780	Loss
AGC_Akt_AKT1_ST	Q9P0N9	TBC1D7	P31749	AKT1	S124	D131V	131	Missense	distal	7	no	12.487	12.509	PhosphoSitePlus	COSMIC	7.780	Up-regulation
AGC_Akt_AKT1_ST	Q05195	MXD1	P31749	AKT1	T94	L97V	97	Missense	distal	3	no	11.703	11.710	EPSD	COSMIC	7.780	Up-regulation
AGC_Akt_AKT1_ST	Q05195	MXD1	P31749	AKT1	T94	R91Q	91	Missense	distal	-3	no	11.703	4.491	EPSD	COSMIC	7.780	Loss
AGC_Akt_AKT1_ST	Q05195	MXD1	P31749	AKT1	T94	S90I	90	Missense	distal	-4	no	11.703	10.321	EPSD	COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	Q05195	MXD1	P31749	AKT1	T94	E88K	88	Missense	distal	-6	no	11.703	11.769	EPSD	COSMIC	7.780	Up-regulation
AGC_Akt_AKT1_ST	Q05195	MXD1	P31749	AKT1	T94	R91G	91	Missense	distal	-3	no	11.703	4.947	EPSD	COSMIC;GDSC;CCLE	7.780	Loss
AGC_Akt_AKT1_ST	Q05195	MXD1	P31749	AKT1	S96	L97V	97	Missense	proximal	1	no	9.660	9.560	EPSD	COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	Q05195	MXD1	P31749	AKT1	S96	R91Q	91	Missense	distal	-5	no	9.660	5.432	EPSD	COSMIC	7.780	Loss
AGC_Akt_AKT1_ST	Q05195	MXD1	P31749	AKT1	S96	S90I	90	Missense	distal	-6	no	9.660	9.540	EPSD	COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	Q05195	MXD1	P31749	AKT1	S96	R91G	91	Missense	distal	-5	no	9.660	5.595	EPSD	COSMIC;GDSC;CCLE	7.780	Loss
AGC_Akt_AKT1_ST	Q05195	MXD1	P31749	AKT1	S145	E139Q	139	Missense	distal	-6	no	14.110	14.106	PhosphoSitePlus	COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	Q05195	MXD1	P31749	AKT1	S145	S151F	151	Missense	distal	6	no	14.110	13.990	PhosphoSitePlus	COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	Q05195	MXD1	P31749	AKT1	S145	R142Q	142	Missense	distal	-3	no	14.110	6.899	PhosphoSitePlus	COSMIC	7.780	Loss
AGC_Akt_AKT1_ST	Q05195	MXD1	P31749	AKT1	S145	S145F	145	Missense	central	0	yes	14.110	0.000	PhosphoSitePlus	COSMIC	7.780	Loss
AGC_Akt_AKT1_ST	Q05195	MXD1	P31749	AKT1	S145	T149I	149	Missense	distal	4	no	14.110	14.376	PhosphoSitePlus	COSMIC	7.780	Up-regulation
AGC_Akt_AKT1_ST	Q05195	MXD1	P31749	AKT1	S194	M192I	192	Missense	proximal	-2	no	8.343	7.942	EPSD	COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	Q05195	MXD1	P31749	AKT1	S194	S191R	191	Missense	distal	-3	no	8.343	16.119	EPSD	COSMIC	7.780	Up-regulation
AGC_Akt_AKT1_ST	Q05195	MXD1	P31749	AKT1	S194	R189W	189	Missense	distal	-5	no	8.343	2.823	EPSD	COSMIC	7.780	Loss
AGC_Akt_AKT1_ST	P62753	RPS6	P31749	AKT1	T34	M32L	32	Missense	proximal	-2	no	11.725	11.708	EPSD	COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	P62753	RPS6	P31749	AKT1	T34	F27L	27	Missense	distal	-7	no	11.725	11.769	EPSD	COSMIC	7.780	Up-regulation
AGC_Akt_AKT1_ST	P62753	RPS6	P31749	AKT1	T181	I176V	176	Missense	distal	-5	no	9.580	9.833	EPSD	COSMIC	7.780	Up-regulation
AGC_Akt_AKT1_ST	P62753	RPS6	P31749	AKT1	T181	V184L	184	Missense	distal	3	no	9.580	9.572	EPSD	COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	Q14457	BECN1	P31749	AKT1	S10	K5R	5	Missense	distal	-5	no	8.163	10.560	EPSD	COSMIC	7.780	Up-regulation
AGC_Akt_AKT1_ST	Q14457	BECN1	P31749	AKT1	T119	L122P	122	Missense	distal	3	no	9.392	9.408	EPSD	COSMIC	7.780	Up-regulation
AGC_Akt_AKT1_ST	Q14457	BECN1	P31749	AKT1	T119	D124E	124	Missense	distal	5	no	9.392	9.434	EPSD	COSMIC	7.780	Up-regulation
AGC_Akt_AKT1_ST	Q14457	BECN1	P31749	AKT1	S234	Q240H	240	Missense	distal	6	no	10.326	10.277	EPSD	COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	Q9Y5S9	RBM8A	P31749	AKT1	S56	E63K	63	Missense	distal	7	no	8.991	9.025	EPSD	COSMIC	7.780	Up-regulation
AGC_Akt_AKT1_ST	Q9Y5S9	RBM8A	P31749	AKT1	S56	E58K	58	Missense	proximal	2	no	8.991	9.196	EPSD	COSMIC	7.780	Up-regulation
AGC_Akt_AKT1_ST	Q9Y5S9	RBM8A	P31749	AKT1	S166	R165H	165	Missense	proximal	-1	no	15.380	15.336	EPSD	COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	Q9Y5S9	RBM8A	P31749	AKT1	S166	P169S	169	Missense	distal	3	no	15.380	15.461	EPSD	COSMIC	7.780	Up-regulation
AGC_Akt_AKT1_ST	Q9Y5S9	RBM8A	P31749	AKT1	S166	R171W	171	Missense	distal	5	no	15.380	15.286	EPSD	COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	Q9Y5S9	RBM8A	P31749	AKT1	S166	R172H	172	Missense	distal	6	no	15.380	15.261	EPSD	COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	Q9Y5S9	RBM8A	P31749	AKT1	S166	R163I	163	Missense	distal	-3	no	15.380	8.299	EPSD	COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	Q9Y5S9	RBM8A	P31749	AKT1	S166	R159I	159	Missense	distal	-7	no	15.380	14.952	EPSD	COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	Q9Y5S9	RBM8A	P31749	AKT1	S166	R172L	172	Missense	distal	6	no	15.380	15.278	EPSD	COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	Q9Y5S9	RBM8A	P31749	AKT1	S166	R164H	164	Missense	proximal	-2	no	15.380	14.519	EPSD	COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	Q9Y5S9	RBM8A	P31749	AKT1	S166	R171T	171	Missense	distal	5	no	15.380	15.373	EPSD	COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	Q9Y5S9	RBM8A	P31749	AKT1	S168	R165H	165	Missense	distal	-3	no	18.571	13.872	PhosphoSitePlus	COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	Q9Y5S9	RBM8A	P31749	AKT1	S168	P169S	169	Missense	proximal	1	no	18.571	18.726	PhosphoSitePlus	COSMIC	7.780	Up-regulation
AGC_Akt_AKT1_ST	Q9Y5S9	RBM8A	P31749	AKT1	S168	R171W	171	Missense	distal	3	no	18.571	18.459	PhosphoSitePlus	COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	Q9Y5S9	RBM8A	P31749	AKT1	S168	R172H	172	Missense	distal	4	no	18.571	18.755	PhosphoSitePlus	COSMIC	7.780	Up-regulation
AGC_Akt_AKT1_ST	Q9Y5S9	RBM8A	P31749	AKT1	S168	R163I	163	Missense	distal	-5	no	18.571	14.003	PhosphoSitePlus	COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	Q9Y5S9	RBM8A	P31749	AKT1	S168	R172L	172	Missense	distal	4	no	18.571	18.748	PhosphoSitePlus	COSMIC	7.780	Up-regulation
AGC_Akt_AKT1_ST	Q9Y5S9	RBM8A	P31749	AKT1	S168	R164H	164	Missense	distal	-4	no	18.571	17.512	PhosphoSitePlus	COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	Q9Y5S9	RBM8A	P31749	AKT1	S168	R171T	171	Missense	distal	3	no	18.571	18.586	PhosphoSitePlus	COSMIC	7.780	Up-regulation
AGC_Akt_AKT1_ST	P67809	YBX1	P31749	AKT1	S102	T108I	108	Missense	distal	6	no	8.722	8.537	PhosphoSitePlus	COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	O14757	CHEK1	P31749	AKT1	S280	R275S	275	Missense	distal	-5	no	12.979	8.508	PhosphoSitePlus	COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	O14757	CHEK1	P31749	AKT1	S280	P276L	276	Missense	distal	-4	no	12.979	12.591	PhosphoSitePlus	COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	O14757	CHEK1	P31749	AKT1	T382	K375R	375	Missense	distal	-7	no	10.085	10.098	EPSD	COSMIC	7.780	Up-regulation
AGC_Akt_AKT1_ST	O14757	CHEK1	P31749	AKT1	T382	L384F	384	Missense	proximal	2	no	10.085	10.053	EPSD	COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	O14757	CHEK1	P31749	AKT1	T382	M377I	377	Missense	distal	-5	no	10.085	10.040	EPSD	COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	O14757	CHEK1	P31749	AKT1	T382	K375Q	375	Missense	distal	-7	no	10.085	9.904	EPSD	COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	Q13131	PRKAA1	P31749	AKT1	S65	G70A	70	Missense	distal	5	no	11.607	11.619	EPSD	COSMIC	7.780	Up-regulation
AGC_Akt_AKT1_ST	Q13131	PRKAA1	P31749	AKT1	S65	R64W	64	Missense	proximal	-1	no	11.607	11.547	EPSD	COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	Q13131	PRKAA1	P31749	AKT1	S65	R64C	64	Missense	proximal	-1	no	11.607	11.537	EPSD	COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	Q13131	PRKAA1	P31749	AKT1	S496	V497A	497	Missense	proximal	1	no	13.385	13.312	PhosphoSitePlus	COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	Q13131	PRKAA1	P31749	AKT1	S496	R501G	501	Missense	distal	5	no	13.385	13.314	PhosphoSitePlus	COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	Q13131	PRKAA1	P31749	AKT1	S498	V497A	497	Missense	proximal	-1	no	9.782	9.796	EPSD	COSMIC	7.780	Up-regulation
AGC_Akt_AKT1_ST	Q13131	PRKAA1	P31749	AKT1	S498	R501G	501	Missense	distal	3	no	9.782	9.708	EPSD	COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	Q13131	PRKAA1	P31749	AKT1	S498	R505K	505	Missense	distal	7	no	9.782	9.774	EPSD	COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	Q13131	PRKAA1	P31749	AKT1	S498	R505G	505	Missense	distal	7	no	9.782	9.701	EPSD	COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	Q13131	PRKAA1	P31749	AKT1	S506	R501G	501	Missense	distal	-5	no	9.651	5.587	EPSD	COSMIC	7.780	Loss
AGC_Akt_AKT1_ST	Q13131	PRKAA1	P31749	AKT1	S506	R505K	505	Missense	proximal	-1	no	9.651	9.648	EPSD	COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	Q13131	PRKAA1	P31749	AKT1	S506	R505G	505	Missense	proximal	-1	no	9.651	9.611	EPSD	COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	Q13131	PRKAA1	P31749	AKT1	S508	R501G	501	Missense	distal	-7	no	11.164	10.922	EPSD	COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	Q13131	PRKAA1	P31749	AKT1	S508	R505K	505	Missense	distal	-3	no	11.164	6.644	EPSD	COSMIC	7.780	Loss
AGC_Akt_AKT1_ST	Q13131	PRKAA1	P31749	AKT1	S508	R505G	505	Missense	distal	-3	no	11.164	4.408	EPSD	COSMIC	7.780	Loss
AGC_Akt_AKT1_ST	Q13131	PRKAA1	P31749	AKT1	S541	P539S	539	Missense	proximal	-2	no	11.160	11.984	EPSD	COSMIC	7.780	Up-regulation
AGC_Akt_AKT1_ST	Q13131	PRKAA1	P31749	AKT1	S541	P539T	539	Missense	proximal	-2	no	11.160	11.918	EPSD	COSMIC	7.780	Up-regulation
AGC_Akt_AKT1_ST	Q13131	PRKAA1	P31749	AKT1	T543	P539S	539	Missense	distal	-4	no	9.458	10.194	EPSD	COSMIC	7.780	Up-regulation
AGC_Akt_AKT1_ST	Q13131	PRKAA1	P31749	AKT1	T543	P539T	539	Missense	distal	-4	no	9.458	10.250	EPSD	COSMIC	7.780	Up-regulation
AGC_Akt_AKT1_ST	Q9UQC2	GAB2	P31749	AKT1	S132	D126E	126	Missense	distal	-6	no	9.716	9.788	EPSD	COSMIC	7.780	Up-regulation
AGC_Akt_AKT1_ST	Q9UQC2	GAB2	P31749	AKT1	S132	R129S	129	Missense	distal	-3	no	9.716	1.939	EPSD	COSMIC	7.780	Loss
AGC_Akt_AKT1_ST	Q9UQC2	GAB2	P31749	AKT1	S132	P138R	138	Missense	distal	6	no	9.716	9.808	EPSD	COSMIC	7.780	Up-regulation
AGC_Akt_AKT1_ST	Q9UQC2	GAB2	P31749	AKT1	S132	V131I	131	Missense	proximal	-1	no	9.716	9.701	EPSD	COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	Q9UQC2	GAB2	P31749	AKT1	S141	P138R	138	Missense	distal	-3	no	5.646	12.286	EPSD	COSMIC	7.780	Gain
AGC_Akt_AKT1_ST	Q9UQC2	GAB2	P31749	AKT1	S159	S164F	164	Missense	distal	5	no	15.575	15.502	PhosphoSitePlus	COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	Q9UQC2	GAB2	P31749	AKT1	S159	K157N	157	Missense	proximal	-2	no	15.575	14.638	PhosphoSitePlus	COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	Q9UQC2	GAB2	P31749	AKT1	S159	P161L	161	Missense	proximal	2	no	15.575	15.366	PhosphoSitePlus	COSMIC;GDSC;CCLE	7.780	Down-regulation
AGC_Akt_AKT1_ST	Q9UQC2	GAB2	P31749	AKT1	S159	R154Q	154	Missense	distal	-5	no	15.575	11.347	PhosphoSitePlus	COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	Q9UQC2	GAB2	P31749	AKT1	S159	R156H	156	Missense	distal	-3	no	15.575	10.876	PhosphoSitePlus	COSMIC;GDSC;CCLE	7.780	Down-regulation
AGC_Akt_AKT1_ST	Q9UQC2	GAB2	P31749	AKT1	S159	S162L	162	Missense	distal	3	no	15.575	15.477	PhosphoSitePlus	COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	Q9UQC2	GAB2	P31749	AKT1	T225	Q232R	232	Missense	distal	7	no	10.382	10.438	EPSD	COSMIC	7.780	Up-regulation
AGC_Akt_AKT1_ST	Q9UQC2	GAB2	P31749	AKT1	T259	T259M	259	Missense	central	0	yes	10.546	0.000	EPSD	COSMIC	7.780	Loss
AGC_Akt_AKT1_ST	Q9UQC2	GAB2	P31749	AKT1	T259	N258S	258	Missense	proximal	-1	no	10.546	10.564	EPSD	COSMIC	7.780	Up-regulation
AGC_Akt_AKT1_ST	Q9UQC2	GAB2	P31749	AKT1	S264	T259M	259	Missense	distal	-5	no	8.031	7.239	EPSD	COSMIC	7.780	Loss
AGC_Akt_AKT1_ST	Q9UQC2	GAB2	P31749	AKT1	S264	P269S	269	Missense	distal	5	no	8.031	8.084	EPSD	COSMIC	7.780	Up-regulation
AGC_Akt_AKT1_ST	Q9UQC2	GAB2	P31749	AKT1	S264	N258S	258	Missense	distal	-6	no	8.031	8.078	EPSD	COSMIC	7.780	Up-regulation
AGC_Akt_AKT1_ST	Q9UQC2	GAB2	P31749	AKT1	T265	T259M	259	Missense	distal	-6	no	7.788	7.695	EPSD	COSMIC	7.780	Loss
AGC_Akt_AKT1_ST	Q9UQC2	GAB2	P31749	AKT1	T265	P269S	269	Missense	distal	4	no	7.788	7.632	EPSD	COSMIC	7.780	Loss
AGC_Akt_AKT1_ST	Q9UQC2	GAB2	P31749	AKT1	T265	N258S	258	Missense	distal	-7	no	7.788	7.902	EPSD	COSMIC	7.780	Up-regulation
AGC_Akt_AKT1_ST	Q9UQC2	GAB2	P31749	AKT1	T331	T331N	331	Missense	central	0	yes	9.973	0.000	EPSD	COSMIC	7.780	Loss
AGC_Akt_AKT1_ST	Q9UQC2	GAB2	P31749	AKT1	S368	Q370R	370	Missense	proximal	2	no	10.747	10.864	EPSD	COSMIC	7.780	Up-regulation
AGC_Akt_AKT1_ST	Q9UQC2	GAB2	P31749	AKT1	S368	G367D	367	Missense	proximal	-1	no	10.747	10.728	EPSD	COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	Q9UQC2	GAB2	P31749	AKT1	T385	S379I	379	Missense	distal	-6	no	9.593	9.473	EPSD	COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	Q9UQC2	GAB2	P31749	AKT1	T385	A383T	383	Missense	proximal	-2	no	9.593	9.979	EPSD	COSMIC	7.780	Up-regulation
AGC_Akt_AKT1_ST	Q9UQC2	GAB2	P31749	AKT1	T385	L392P	392	Missense	distal	7	no	9.593	9.601	EPSD	COSMIC	7.780	Up-regulation
AGC_Akt_AKT1_ST	Q9UQC2	GAB2	P31749	AKT1	T391	L392P	392	Missense	proximal	1	no	9.409	9.155	EPSD	COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	Q9UQC2	GAB2	P31749	AKT1	S404	S405L	405	Missense	proximal	1	no	10.238	10.336	EPSD	COSMIC	7.780	Up-regulation
AGC_Akt_AKT1_ST	Q9UQC2	GAB2	P31749	AKT1	S404	R399Q	399	Missense	distal	-5	no	10.238	6.010	EPSD	COSMIC	7.780	Loss
AGC_Akt_AKT1_ST	Q9UQC2	GAB2	P31749	AKT1	S405	S405L	405	Missense	central	0	yes	11.247	0.000	EPSD	COSMIC	7.780	Loss
AGC_Akt_AKT1_ST	Q9UQC2	GAB2	P31749	AKT1	S405	R399Q	399	Missense	distal	-6	no	11.247	11.162	EPSD	COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	Q9UQC2	GAB2	P31749	AKT1	S425	G420R	420	Missense	distal	-5	no	4.946	9.011	EPSD	COSMIC	7.780	Gain
AGC_Akt_AKT1_ST	Q9UQC2	GAB2	P31749	AKT1	S445	S443L	443	Missense	proximal	-2	no	11.344	10.487	EPSD	COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	Q9UQC2	GAB2	P31749	AKT1	S445	D444Y	444	Missense	proximal	-1	no	11.344	11.366	EPSD	COSMIC	7.780	Up-regulation
AGC_Akt_AKT1_ST	Q9UQC2	GAB2	P31749	AKT1	S445	S448Y	448	Missense	distal	3	no	11.344	11.275	EPSD	COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	Q9UQC2	GAB2	P31749	AKT1	S445	R442Q	442	Missense	distal	-3	no	11.344	4.132	EPSD	COSMIC;GDSC	7.780	Loss
AGC_Akt_AKT1_ST	Q9UQC2	GAB2	P31749	AKT1	S472	A468S	468	Missense	distal	-4	no	7.480	8.202	EPSD	COSMIC	7.780	Gain
AGC_Akt_AKT1_ST	Q9UQC2	GAB2	P31749	AKT1	S503	S503R	503	Missense	central	0	yes	10.024	0.000	EPSD	COSMIC;CCLE	7.780	Loss
AGC_Akt_AKT1_ST	Q9UQC2	GAB2	P31749	AKT1	S503	P497H	497	Missense	distal	-6	no	10.024	10.003	EPSD	COSMIC;GDSC;CCLE	7.780	Down-regulation
AGC_Akt_AKT1_ST	Q9UQC2	GAB2	P31749	AKT1	S503	G505A	505	Missense	proximal	2	no	10.024	9.980	EPSD	COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	Q9UQC2	GAB2	P31749	AKT1	S503	R500L	500	Missense	distal	-3	no	10.024	3.030	EPSD	COSMIC	7.780	Loss
AGC_Akt_AKT1_ST	Q9UQC2	GAB2	P31749	AKT1	S503	G505E	505	Missense	proximal	2	no	10.024	10.167	EPSD	COSMIC	7.780	Up-regulation
AGC_Akt_AKT1_ST	Q9UQC2	GAB2	P31749	AKT1	S506	S503R	503	Missense	distal	-3	no	2.872	10.648	EPSD	COSMIC;CCLE	7.780	Gain
AGC_Akt_AKT1_ST	Q9UQC2	GAB2	P31749	AKT1	T534	V535I	535	Missense	proximal	1	no	8.861	8.613	EPSD	COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	Q9UQC2	GAB2	P31749	AKT1	T534	D537G	537	Missense	distal	3	no	8.861	8.882	EPSD	COSMIC	7.780	Up-regulation
AGC_Akt_AKT1_ST	Q9UQC2	GAB2	P31749	AKT1	T534	R531S	531	Missense	distal	-3	no	8.861	1.084	EPSD	COSMIC	7.780	Loss
AGC_Akt_AKT1_ST	Q9UQC2	GAB2	P31749	AKT1	T534	E538K	538	Missense	distal	4	no	8.861	8.760	EPSD	COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	Q9UQC2	GAB2	P31749	AKT1	S550	R551K	551	Missense	proximal	1	no	8.746	8.669	EPSD	COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	Q9UQC2	GAB2	P31749	AKT1	S550	P544H	544	Missense	distal	-6	no	8.746	8.725	EPSD	COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	Q9UQC2	GAB2	P31749	AKT1	S550	A552V	552	Missense	proximal	2	no	8.746	8.584	EPSD	COSMIC;GDSC;CCLE	7.780	Down-regulation
AGC_Akt_AKT1_ST	Q9UQC2	GAB2	P31749	AKT1	S550	R551S	551	Missense	proximal	1	no	8.746	8.601	EPSD	COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	Q9UQC2	GAB2	P31749	AKT1	S631	V635I	635	Missense	distal	4	no	13.738	13.820	EPSD	COSMIC	7.780	Up-regulation
AGC_Akt_AKT1_ST	Q9UQC2	GAB2	P31749	AKT1	S631	S631C	631	Missense	central	0	yes	13.738	0.000	EPSD	COSMIC	7.780	Loss
AGC_Akt_AKT1_ST	Q9UQC2	GAB2	P31749	AKT1	S633	V635I	635	Missense	proximal	2	no	9.200	9.082	EPSD	COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	Q9UQC2	GAB2	P31749	AKT1	S633	S631C	631	Missense	proximal	-2	no	9.200	7.548	EPSD	COSMIC	7.780	Loss
AGC_Akt_AKT1_ST	P23769	GATA2	P31749	AKT1	S182	T188M	188	Missense	distal	6	no	8.663	8.543	EPSD	COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	P23769	GATA2	P31749	AKT1	S182	D184N	184	Missense	proximal	2	no	8.663	8.993	EPSD	COSMIC	7.780	Up-regulation
AGC_Akt_AKT1_ST	P23769	GATA2	P31749	AKT1	S182	P177Q	177	Missense	distal	-5	no	8.663	8.445	EPSD	COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	P23769	GATA2	P31749	AKT1	S288	R293W	293	Missense	distal	5	no	12.407	12.312	EPSD	COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	P23769	GATA2	P31749	AKT1	S288	R293Q	293	Missense	distal	5	no	12.407	12.356	EPSD	COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	P23769	GATA2	P31749	AKT1	S290	R293W	293	Missense	distal	3	no	13.645	13.533	EPSD	COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	P23769	GATA2	P31749	AKT1	S290	N297K	297	Missense	distal	7	no	13.645	13.680	EPSD	COSMIC	7.780	Up-regulation
AGC_Akt_AKT1_ST	P23769	GATA2	P31749	AKT1	S290	R293Q	293	Missense	distal	3	no	13.645	13.589	EPSD	COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	P23769	GATA2	P31749	AKT1	S290	N297S	297	Missense	distal	7	no	13.645	13.680	EPSD	COSMIC	7.780	Up-regulation
AGC_Akt_AKT1_ST	P23769	GATA2	P31749	AKT1	S340	K334T	334	Missense	distal	-6	no	10.890	10.901	EPSD	COSMIC	7.780	Up-regulation
AGC_Akt_AKT1_ST	P23769	GATA2	P31749	AKT1	S340	G346V	346	Missense	distal	6	no	10.890	10.882	EPSD	COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	P23769	GATA2	P31749	AKT1	S340	T347A	347	Missense	distal	7	no	10.890	10.830	EPSD	COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	P23769	GATA2	P31749	AKT1	S401	S404T	404	Missense	distal	3	no	16.125	16.124	PhosphoSitePlus	COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	P23769	GATA2	P31749	AKT1	S401	K405E	405	Missense	distal	4	no	16.125	16.226	PhosphoSitePlus	COSMIC	7.780	Up-regulation
AGC_Akt_AKT1_ST	P23769	GATA2	P31749	AKT1	S401	R396L	396	Missense	distal	-5	no	16.125	11.999	PhosphoSitePlus	COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	P23769	GATA2	P31749	AKT1	S401	M400L	400	Missense	proximal	-1	no	16.125	16.126	PhosphoSitePlus	COSMIC;GDSC;CCLE	7.780	Up-regulation
AGC_Akt_AKT1_ST	P23769	GATA2	P31749	AKT1	S401	R398W	398	Missense	distal	-3	no	16.125	7.185	PhosphoSitePlus	COSMIC	7.780	Loss
AGC_Akt_AKT1_ST	P23769	GATA2	P31749	AKT1	S401	S401Y	401	Missense	central	0	yes	16.125	0.000	PhosphoSitePlus	COSMIC	7.780	Loss
AGC_Akt_AKT1_ST	P41002	CCNF	P31749	AKT1	S754	S758R	758	Missense	distal	4	no	10.612	10.623	EPSD	COSMIC	7.780	Up-regulation
AGC_Akt_AKT1_ST	Q05397	PTK2	P31749	AKT1	T24	L22F	22	Missense	proximal	-2	no	8.787	8.777	EPSD	COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	Q05397	PTK2	P31749	AKT1	T24	R28H	28	Missense	distal	4	no	8.787	8.972	EPSD	COSMIC	7.780	Up-regulation
AGC_Akt_AKT1_ST	Q05397	PTK2	P31749	AKT1	S239	E245K	245	Missense	distal	6	no	10.719	10.789	EPSD	COSMIC	7.780	Up-regulation
AGC_Akt_AKT1_ST	Q05397	PTK2	P31749	AKT1	S239	L241P	241	Missense	proximal	2	no	10.719	10.928	EPSD	COSMIC	7.780	Up-regulation
AGC_Akt_AKT1_ST	Q05397	PTK2	P31749	AKT1	S390	S390A	390	Missense	central	0	yes	10.293	0.000	EPSD	COSMIC	7.780	Loss
AGC_Akt_AKT1_ST	Q05397	PTK2	P31749	AKT1	S390	V391A	391	Missense	proximal	1	no	10.293	10.220	EPSD	COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	Q05397	PTK2	P31749	AKT1	S390	A388T	388	Missense	proximal	-2	no	10.293	10.678	EPSD	COSMIC	7.780	Up-regulation
AGC_Akt_AKT1_ST	Q05397	PTK2	P31749	AKT1	S517	D519H	519	Missense	proximal	2	no	12.096	12.161	EPSD	COSMIC	7.780	Up-regulation
AGC_Akt_AKT1_ST	Q05397	PTK2	P31749	AKT1	S517	S522C	522	Missense	distal	5	no	12.096	11.977	EPSD	COSMIC;GDSC;CCLE	7.780	Down-regulation
AGC_Akt_AKT1_ST	Q05397	PTK2	P31749	AKT1	S574	R569L	569	Missense	distal	-5	no	7.896	3.770	EPSD	COSMIC	7.780	Loss
AGC_Akt_AKT1_ST	Q05397	PTK2	P31749	AKT1	S574	A579V	579	Missense	distal	5	no	7.896	7.887	EPSD	COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	Q05397	PTK2	P31749	AKT1	S695	R690L	690	Missense	distal	-5	no	15.318	11.192	PhosphoSitePlus;EPSD	COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	Q05397	PTK2	P31749	AKT1	S695	R692K	692	Missense	distal	-3	no	15.318	10.798	PhosphoSitePlus;EPSD	COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	Q05397	PTK2	P31749	AKT1	S695	T700M	700	Missense	distal	5	no	15.318	15.261	PhosphoSitePlus;EPSD	COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	Q05397	PTK2	P31749	AKT1	T700	G706R	706	Missense	distal	6	no	11.391	11.495	EPSD;PhosphoSitePlus	COSMIC	7.780	Up-regulation
AGC_Akt_AKT1_ST	Q05397	PTK2	P31749	AKT1	T700	T700M	700	Missense	central	0	yes	11.391	0.000	EPSD;PhosphoSitePlus	COSMIC	7.780	Loss
AGC_Akt_AKT1_ST	Q05397	PTK2	P31749	AKT1	S702	G706R	706	Missense	distal	4	no	8.751	8.589	EPSD	COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	Q05397	PTK2	P31749	AKT1	S702	S708R	708	Missense	distal	6	no	8.751	8.750	EPSD	COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	Q05397	PTK2	P31749	AKT1	S702	T700M	700	Missense	proximal	-2	no	8.751	7.978	EPSD	COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	Q05397	PTK2	P31749	AKT1	S722	G728E	728	Missense	distal	6	no	9.370	9.417	EPSD	COSMIC	7.780	Up-regulation
AGC_Akt_AKT1_ST	Q05397	PTK2	P31749	AKT1	S722	S722I	722	Missense	central	0	yes	9.370	0.000	EPSD	COSMIC	7.780	Loss
AGC_Akt_AKT1_ST	P54253	ATXN1	P31749	AKT1	T22	R17Q	17	Missense	distal	-5	no	8.868	4.641	EPSD	COSMIC	7.780	Loss
AGC_Akt_AKT1_ST	P54253	ATXN1	P31749	AKT1	T22	R24P	24	Missense	proximal	2	no	8.868	8.704	EPSD	COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	P54253	ATXN1	P31749	AKT1	T22	S26F	26	Missense	distal	4	no	8.868	9.064	EPSD	COSMIC	7.780	Up-regulation
AGC_Akt_AKT1_ST	P54253	ATXN1	P31749	AKT1	S252	Y247H	247	Missense	distal	-5	no	6.415	7.928	EPSD	COSMIC	7.780	Gain
AGC_Akt_AKT1_ST	P54253	ATXN1	P31749	AKT1	S262	G258C	258	Missense	distal	-4	no	12.639	11.775	EPSD	COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	P54253	ATXN1	P31749	AKT1	S312	K307R	307	Missense	distal	-5	no	8.426	10.823	EPSD	COSMIC	7.780	Up-regulation
AGC_Akt_AKT1_ST	P54253	ATXN1	P31749	AKT1	S406	E404D	404	Missense	proximal	-2	no	12.949	11.964	EPSD	COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	P54253	ATXN1	P31749	AKT1	S406	R403H	403	Missense	distal	-3	no	12.949	8.250	EPSD	COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	P54253	ATXN1	P31749	AKT1	S406	D412N	412	Missense	distal	6	no	12.949	13.031	EPSD	COSMIC	7.780	Up-regulation
AGC_Akt_AKT1_ST	P54253	ATXN1	P31749	AKT1	S406	A405T	405	Missense	proximal	-1	no	12.949	12.976	EPSD	COSMIC	7.780	Up-regulation
AGC_Akt_AKT1_ST	P54253	ATXN1	P31749	AKT1	S406	L410V	410	Missense	distal	4	no	12.949	12.941	EPSD	COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	P54253	ATXN1	P31749	AKT1	S408	E404D	404	Missense	distal	-4	no	8.502	7.726	EPSD	COSMIC	7.780	Loss
AGC_Akt_AKT1_ST	P54253	ATXN1	P31749	AKT1	S408	R403H	403	Missense	distal	-5	no	8.502	5.408	EPSD	COSMIC	7.780	Loss
AGC_Akt_AKT1_ST	P54253	ATXN1	P31749	AKT1	S408	D412N	412	Missense	distal	4	no	8.502	8.387	EPSD	COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	P54253	ATXN1	P31749	AKT1	S408	G415D	415	Missense	distal	7	no	8.502	8.499	EPSD	COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	P54253	ATXN1	P31749	AKT1	S408	A405T	405	Missense	distal	-3	no	8.502	7.784	EPSD	COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	P54253	ATXN1	P31749	AKT1	S408	L410V	410	Missense	proximal	2	no	8.502	8.510	EPSD	COSMIC	7.780	Up-regulation
AGC_Akt_AKT1_ST	Q9BRS8	LARP6	P31749	AKT1	S51	P46S	46	Missense	distal	-5	no	10.446	9.986	EPSD	COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	Q9BRS8	LARP6	P31749	AKT1	S247	P241L	241	Missense	distal	-6	no	11.465	11.478	EPSD	COSMIC;CCLE	7.780	Up-regulation
AGC_Akt_AKT1_ST	Q9BRS8	LARP6	P31749	AKT1	S247	P241S	241	Missense	distal	-6	no	11.465	11.529	EPSD	COSMIC	7.780	Up-regulation
AGC_Akt_AKT1_ST	Q9BRS8	LARP6	P31749	AKT1	S247	V253L	253	Missense	distal	6	no	11.465	11.475	EPSD	COSMIC	7.780	Up-regulation
AGC_Akt_AKT1_ST	Q9BRS8	LARP6	P31749	AKT1	S247	R244W	244	Missense	distal	-3	no	11.465	2.524	EPSD	COSMIC	7.780	Loss
AGC_Akt_AKT1_ST	Q9BRS8	LARP6	P31749	AKT1	S384	T379R	379	Missense	distal	-5	no	5.671	9.400	EPSD	COSMIC	7.780	Gain
AGC_Akt_AKT1_ST	Q9BRS8	LARP6	P31749	AKT1	S451	P448R	448	Missense	distal	-3	no	7.702	14.342	PhosphoSitePlus	COSMIC	7.780	Gain
AGC_Akt_AKT1_ST	P07550	ADRB2	P31749	AKT1	T68	T66M	66	Missense	proximal	-2	no	8.233	7.460	EPSD	COSMIC	7.780	Loss
AGC_Akt_AKT1_ST	P07550	ADRB2	P31749	AKT1	T68	R63C	63	Missense	distal	-5	no	8.233	4.157	EPSD	COSMIC;CCLE	7.780	Loss
AGC_Akt_AKT1_ST	P07550	ADRB2	P31749	AKT1	S262	C265S	265	Missense	distal	3	no	12.766	12.943	EPSD	COSMIC	7.780	Up-regulation
AGC_Akt_AKT1_ST	P07550	ADRB2	P31749	AKT1	S262	S261F	261	Missense	proximal	-1	no	12.766	12.732	EPSD	COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	P07550	ADRB2	P31749	AKT1	S346	R343H	343	Missense	distal	-3	no	13.056	8.357	PhosphoSitePlus	COSMIC;GDSC;CCLE	7.780	Down-regulation
AGC_Akt_AKT1_ST	P07550	ADRB2	P31749	AKT1	S346	S345Y	345	Missense	proximal	-1	no	13.056	13.030	PhosphoSitePlus	COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	P07550	ADRB2	P31749	AKT1	S407	R404W	404	Missense	distal	-3	no	13.355	4.414	EPSD	COSMIC;CCLE	7.780	Loss
AGC_Akt_AKT1_ST	P07550	ADRB2	P31749	AKT1	S407	N409S	409	Missense	proximal	2	no	13.355	13.623	EPSD	COSMIC	7.780	Up-regulation
AGC_Akt_AKT1_ST	P07550	ADRB2	P31749	AKT1	S407	S407N	407	Missense	central	0	yes	13.355	0.000	EPSD	COSMIC	7.780	Loss
AGC_Akt_AKT1_ST	P54578	USP14	P31749	AKT1	S230	S230R	230	Missense	central	0	yes	8.882	0.000	EPSD	COSMIC	7.780	Loss
AGC_Akt_AKT1_ST	P54578	USP14	P31749	AKT1	S230	S230F	230	Missense	central	0	yes	8.882	0.000	EPSD	COSMIC	7.780	Loss
AGC_Akt_AKT1_ST	P54578	USP14	P31749	AKT1	S230	P236T	236	Missense	distal	6	no	8.882	8.996	EPSD	COSMIC	7.780	Up-regulation
AGC_Akt_AKT1_ST	P54578	USP14	P31749	AKT1	S338	E335D	335	Missense	distal	-3	no	7.320	7.941	EPSD	COSMIC;GDSC;CCLE	7.780	Gain
AGC_Akt_AKT1_ST	P54578	USP14	P31749	AKT1	S394	D390N	390	Missense	distal	-4	no	7.190	7.911	EPSD	COSMIC	7.780	Gain
AGC_Akt_AKT1_ST	P04150	NR3C1	P31749	AKT1	S16	R23K	23	Missense	distal	7	no	8.249	8.242	EPSD	COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	P04150	NR3C1	P31749	AKT1	S16	R11I	11	Missense	distal	-5	no	8.249	3.682	EPSD	COSMIC;GDSC;CCLE	7.780	Loss
AGC_Akt_AKT1_ST	P04150	NR3C1	P31749	AKT1	S16	P15L	15	Missense	proximal	-1	no	8.249	8.250	EPSD	COSMIC	7.780	Up-regulation
AGC_Akt_AKT1_ST	P04150	NR3C1	P31749	AKT1	S134	E137D	137	Missense	distal	3	no	12.534	12.463	PhosphoSitePlus	COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	P04150	NR3C1	P31749	AKT1	S134	S132L	132	Missense	proximal	-2	no	12.534	11.677	PhosphoSitePlus	COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	P04150	NR3C1	P31749	AKT1	S404	P405T	405	Missense	proximal	1	no	10.029	10.377	EPSD	COSMIC	7.780	Up-regulation
AGC_Akt_AKT1_ST	Q9H4A3	WNK1	P31749	AKT1	S10	P13L	13	Missense	distal	3	no	8.025	8.009	EPSD	COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	Q9H4A3	WNK1	P31749	AKT1	S11	P13L	13	Missense	proximal	2	no	8.753	8.544	EPSD	COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	Q9H4A3	WNK1	P31749	AKT1	T60	R58Q	58	Missense	proximal	-2	no	14.328	13.815	PhosphoSitePlus	COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	Q9H4A3	WNK1	P31749	AKT1	S167	S167F	167	Missense	central	0	yes	12.586	0.000	EPSD	COSMIC	7.780	Loss
AGC_Akt_AKT1_ST	Q9H4A3	WNK1	P31749	AKT1	S167	V166L	166	Missense	proximal	-1	no	12.586	12.593	EPSD	COSMIC	7.780	Up-regulation
AGC_Akt_AKT1_ST	Q9H4A3	WNK1	P31749	AKT1	S306	L303R	303	Missense	distal	-3	no	5.244	12.238	EPSD	COSMIC	7.780	Gain
AGC_Akt_AKT1_ST	Q9H4A3	WNK1	P31749	AKT1	T308	L303R	303	Missense	distal	-5	no	4.321	8.447	EPSD	COSMIC	7.780	Gain
AGC_Akt_AKT1_ST	Q9H4A3	WNK1	P31749	AKT1	S378	L374R	374	Missense	distal	-4	no	8.741	9.951	EPSD	COSMIC	7.780	Up-regulation
AGC_Akt_AKT1_ST	Q9H4A3	WNK1	P31749	AKT1	S378	A372P	372	Missense	distal	-6	no	8.741	8.732	EPSD	COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	Q9H4A3	WNK1	P31749	AKT1	S378	S378P	378	Missense	central	0	yes	8.741	0.000	EPSD	COSMIC	7.780	Loss
AGC_Akt_AKT1_ST	Q9H4A3	WNK1	P31749	AKT1	T436	S437R	437	Missense	proximal	1	no	9.482	9.627	EPSD	COSMIC	7.780	Up-regulation
AGC_Akt_AKT1_ST	Q9H4A3	WNK1	P31749	AKT1	T436	S443T	443	Missense	distal	7	no	9.482	9.492	EPSD	COSMIC	7.780	Up-regulation
AGC_Akt_AKT1_ST	Q9H4A3	WNK1	P31749	AKT1	T436	V439A	439	Missense	distal	3	no	9.482	9.514	EPSD	COSMIC	7.780	Up-regulation
AGC_Akt_AKT1_ST	Q9H4A3	WNK1	P31749	AKT1	T436	A429V	429	Missense	distal	-7	no	9.482	9.354	EPSD	COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	Q9H4A3	WNK1	P31749	AKT1	S437	S437R	437	Missense	central	0	yes	11.159	0.000	EPSD	COSMIC	7.780	Loss
AGC_Akt_AKT1_ST	Q9H4A3	WNK1	P31749	AKT1	S437	S443T	443	Missense	distal	6	no	11.159	11.180	EPSD	COSMIC	7.780	Up-regulation
AGC_Akt_AKT1_ST	Q9H4A3	WNK1	P31749	AKT1	S437	V439A	439	Missense	proximal	2	no	11.159	11.322	EPSD	COSMIC	7.780	Up-regulation
AGC_Akt_AKT1_ST	Q9H4A3	WNK1	P31749	AKT1	S443	S437R	437	Missense	distal	-6	no	8.050	8.085	EPSD	COSMIC	7.780	Up-regulation
AGC_Akt_AKT1_ST	Q9H4A3	WNK1	P31749	AKT1	S443	P450L	450	Missense	distal	7	no	8.050	8.042	EPSD	COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	Q9H4A3	WNK1	P31749	AKT1	S443	V439A	439	Missense	distal	-4	no	8.050	8.422	EPSD	COSMIC	7.780	Up-regulation
AGC_Akt_AKT1_ST	Q9H4A3	WNK1	P31749	AKT1	S1105	R1100Q	1100	Missense	distal	-5	no	9.494	5.267	EPSD	COSMIC	7.780	Loss
AGC_Akt_AKT1_ST	Q9H4A3	WNK1	P31749	AKT1	S1105	S1110C	1110	Missense	distal	5	no	9.494	9.376	EPSD	COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	Q9H4A3	WNK1	P31749	AKT1	S1105	H1112Y	1112	Missense	distal	7	no	9.494	9.516	EPSD	COSMIC;GDSC;CCLE	7.780	Up-regulation
AGC_Akt_AKT1_ST	Q9H4A3	WNK1	P31749	AKT1	S1105	R1107K	1107	Missense	proximal	2	no	9.494	9.683	EPSD	COSMIC	7.780	Up-regulation
AGC_Akt_AKT1_ST	Q9H4A3	WNK1	P31749	AKT1	S1105	T1098I	1098	Missense	distal	-7	no	9.494	9.072	EPSD	COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	Q9H4A3	WNK1	P31749	AKT1	S1108	S1110C	1110	Missense	proximal	2	no	9.070	8.245	EPSD	COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	Q9H4A3	WNK1	P31749	AKT1	S1108	H1112Y	1112	Missense	distal	4	no	9.070	9.010	EPSD	COSMIC;GDSC;CCLE	7.780	Down-regulation
AGC_Akt_AKT1_ST	Q9H4A3	WNK1	P31749	AKT1	S1108	R1107K	1107	Missense	proximal	-1	no	9.070	9.066	EPSD	COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	Q9H4A3	WNK1	P31749	AKT1	S1110	S1110C	1110	Missense	central	0	yes	10.716	0.000	EPSD	COSMIC	7.780	Loss
AGC_Akt_AKT1_ST	Q9H4A3	WNK1	P31749	AKT1	S1110	H1112Y	1112	Missense	proximal	2	no	10.716	10.877	EPSD	COSMIC;GDSC;CCLE	7.780	Up-regulation
AGC_Akt_AKT1_ST	Q9H4A3	WNK1	P31749	AKT1	S1110	R1107K	1107	Missense	distal	-3	no	10.716	6.196	EPSD	COSMIC	7.780	Loss
AGC_Akt_AKT1_ST	Q9H4A3	WNK1	P31749	AKT1	S1116	S1110C	1110	Missense	distal	-6	no	10.085	9.939	EPSD	COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	Q9H4A3	WNK1	P31749	AKT1	S1116	H1112Y	1112	Missense	distal	-4	no	10.085	10.198	EPSD	COSMIC;GDSC;CCLE	7.780	Up-regulation
AGC_Akt_AKT1_ST	Q9H4A3	WNK1	P31749	AKT1	S1116	R1121S	1121	Missense	distal	5	no	10.085	10.077	EPSD	COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	Q9H4A3	WNK1	P31749	AKT1	S1261	P1262L	1262	Missense	proximal	1	no	10.878	11.132	EPSD	COSMIC	7.780	Up-regulation
AGC_Akt_AKT1_ST	Q9H4A3	WNK1	P31749	AKT1	S1261	R1267Q	1267	Missense	distal	6	no	10.878	10.807	EPSD	COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	Q9H4A3	WNK1	P31749	AKT1	S1805	Q1799E	1799	Missense	distal	-6	no	13.675	13.679	EPSD	COSMIC;GDSC;CCLE	7.780	Up-regulation
AGC_Akt_AKT1_ST	Q9H4A3	WNK1	P31749	AKT1	S1805	M1808I	1808	Missense	distal	3	no	13.675	13.629	EPSD	COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	Q9H4A3	WNK1	P31749	AKT1	S1805	L1804F	1804	Missense	proximal	-1	no	13.675	13.669	EPSD	COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	Q9H4A3	WNK1	P31749	AKT1	S1961	K1966E	1966	Missense	distal	5	no	8.137	8.104	EPSD	COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	Q9H4A3	WNK1	P31749	AKT1	S1961	G1956S	1956	Missense	distal	-5	no	8.137	7.731	EPSD	COSMIC	7.780	Loss
AGC_Akt_AKT1_ST	Q9H4A3	WNK1	P31749	AKT1	S2051	Q2048K	2048	Missense	distal	-3	no	6.972	9.663	EPSD	COSMIC;GDSC;CCLE	7.780	Gain
AGC_Akt_AKT1_ST	Q9H4A3	WNK1	P31749	AKT1	T2128	K2131N	2131	Missense	distal	3	no	15.861	15.802	EPSD	COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	Q9H4A3	WNK1	P31749	AKT1	T2128	S2135C	2135	Missense	distal	7	no	15.861	15.739	EPSD	COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	Q9H4A3	WNK1	P31749	AKT1	T2128	K2134R	2134	Missense	distal	6	no	15.861	15.849	EPSD	COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	Q9H4A3	WNK1	P31749	AKT1	S2139	K2134R	2134	Missense	distal	-5	no	6.611	9.008	EPSD	COSMIC	7.780	Gain
AGC_Akt_AKT1_ST	Q9H4A3	WNK1	P31749	AKT1	S2140	P2146H	2146	Missense	distal	6	no	11.743	11.716	EPSD	COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	Q9H4A3	WNK1	P31749	AKT1	S2140	S2135C	2135	Missense	distal	-5	no	11.743	12.137	EPSD	COSMIC	7.780	Up-regulation
AGC_Akt_AKT1_ST	Q9H4A3	WNK1	P31749	AKT1	S2140	K2134R	2134	Missense	distal	-6	no	11.743	11.757	EPSD	COSMIC	7.780	Up-regulation
AGC_Akt_AKT1_ST	Q9H4A3	WNK1	P31749	AKT1	S2140	K2144E	2144	Missense	distal	4	no	11.743	11.844	EPSD	COSMIC;GDSC;CCLE	7.780	Up-regulation
AGC_Akt_AKT1_ST	Q9H4A3	WNK1	P31749	AKT1	T2245	D2249N	2249	Missense	distal	4	no	11.901	11.786	EPSD	COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	Q9H4A3	WNK1	P31749	AKT1	T2245	D2248H	2248	Missense	distal	3	no	11.901	11.913	EPSD	COSMIC	7.780	Up-regulation
AGC_Akt_AKT1_ST	Q9H4A3	WNK1	P31749	AKT1	T2247	D2249N	2249	Missense	proximal	2	no	8.204	8.534	EPSD	COSMIC	7.780	Up-regulation
AGC_Akt_AKT1_ST	Q9H4A3	WNK1	P31749	AKT1	T2247	D2248H	2248	Missense	proximal	1	no	8.204	8.239	EPSD	COSMIC	7.780	Up-regulation
AGC_Akt_AKT1_ST	Q9H4A3	WNK1	P31749	AKT1	S2270	R2267M	2267	Missense	distal	-3	no	10.968	3.462	EPSD	COSMIC	7.780	Loss
AGC_Akt_AKT1_ST	Q9H4A3	WNK1	P31749	AKT1	S2286	G2289W	2289	Missense	distal	3	no	11.387	11.350	EPSD	COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	Q9H4A3	WNK1	P31749	AKT1	S2286	A2287E	2287	Missense	proximal	1	no	11.387	11.365	EPSD	COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	Q9H4A3	WNK1	P31749	AKT1	S2372	G2376D	2376	Missense	distal	4	no	12.008	12.059	EPSD	COSMIC	7.780	Up-regulation
AGC_Akt_AKT1_ST	Q9NPC1	LTB4R2	P31749	AKT1	S246	G250R	250	Missense	distal	4	no	11.137	10.975	EPSD	COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	Q9NPC1	LTB4R2	P31749	AKT1	T336	L335V	335	Missense	proximal	-1	no	10.072	10.066	EPSD	COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	Q9NPC1	LTB4R2	P31749	AKT1	S342	L335V	335	Missense	distal	-7	no	10.051	10.007	EPSD	COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	Q9NPC1	LTB4R2	P31749	AKT1	S342	G348D	348	Missense	distal	6	no	10.051	10.007	EPSD	COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	Q9NPC1	LTB4R2	P31749	AKT1	T355	L358P	358	Missense	distal	3	no	15.917	15.933	EPSD	COSMIC;GDSC;CCLE	7.780	Up-regulation
AGC_Akt_AKT1_ST	Q9NPC1	LTB4R2	P31749	AKT1	T355	G348D	348	Missense	distal	-7	no	15.917	15.731	EPSD	COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	Q9NPC1	LTB4R2	P31749	AKT1	T355	G354W	354	Missense	proximal	-1	no	15.917	15.896	EPSD	COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	P21333	FLNA	P31749	AKT1	S215	C210R	210	Missense	distal	-5	no	4.278	8.355	EPSD	COSMIC	7.780	Gain
AGC_Akt_AKT1_ST	P21333	FLNA	P31749	AKT1	S343	D337N	337	Missense	distal	-6	no	14.230	14.301	EPSD	COSMIC	7.780	Up-regulation
AGC_Akt_AKT1_ST	P21333	FLNA	P31749	AKT1	S343	N339H	339	Missense	distal	-4	no	14.230	13.823	EPSD	COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	P21333	FLNA	P31749	AKT1	S343	V350L	350	Missense	distal	7	no	14.230	14.218	EPSD	COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	P21333	FLNA	P31749	AKT1	T790	A797S	797	Missense	distal	7	no	8.600	8.651	EPSD	COSMIC	7.780	Up-regulation
AGC_Akt_AKT1_ST	P21333	FLNA	P31749	AKT1	T833	T835M	835	Missense	proximal	2	no	9.292	8.950	EPSD	COSMIC;GDSC;CCLE	7.780	Down-regulation
AGC_Akt_AKT1_ST	P21333	FLNA	P31749	AKT1	S962	S959R	959	Missense	distal	-3	no	4.388	12.164	EPSD	COSMIC	7.780	Gain
AGC_Akt_AKT1_ST	P21333	FLNA	P31749	AKT1	T1377	K1372R	1372	Missense	distal	-5	no	6.847	9.244	EPSD	COSMIC	7.780	Gain
AGC_Akt_AKT1_ST	P21333	FLNA	P31749	AKT1	S1812	G1806V	1806	Missense	distal	-6	no	9.361	9.365	EPSD	COSMIC	7.780	Up-regulation
AGC_Akt_AKT1_ST	P21333	FLNA	P31749	AKT1	S1812	T1805I	1805	Missense	distal	-7	no	9.361	8.938	EPSD	COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	P21333	FLNA	P31749	AKT1	S2152	R2149Q	2149	Missense	distal	-3	no	14.900	7.688	PhosphoSitePlus	COSMIC	7.780	Loss
AGC_Akt_AKT1_ST	P21333	FLNA	P31749	AKT1	S2152	P2151S	2151	Missense	proximal	-1	no	14.900	14.929	PhosphoSitePlus	COSMIC	7.780	Up-regulation
AGC_Akt_AKT1_ST	P21333	FLNA	P31749	AKT1	S2152	V2156I	2156	Missense	distal	4	no	14.900	14.981	PhosphoSitePlus	COSMIC	7.780	Up-regulation
AGC_Akt_AKT1_ST	P21333	FLNA	P31749	AKT1	S2152	R2149W	2149	Missense	distal	-3	no	14.900	5.959	PhosphoSitePlus	COSMIC	7.780	Loss
AGC_Akt_AKT1_ST	P21333	FLNA	P31749	AKT1	S2152	V2153A	2153	Missense	proximal	1	no	14.900	14.827	PhosphoSitePlus	COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	P21333	FLNA	P31749	AKT1	T2336	V2337F	2337	Missense	proximal	1	no	12.361	12.380	EPSD	COSMIC	7.780	Up-regulation
AGC_Akt_AKT1_ST	P21333	FLNA	P31749	AKT1	T2336	V2337I	2337	Missense	proximal	1	no	12.361	12.113	EPSD	COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	P21333	FLNA	P31749	AKT1	T2336	S2343N	2343	Missense	distal	7	no	12.361	12.325	EPSD	COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	P21333	FLNA	P31749	AKT1	S2338	G2344W	2344	Missense	distal	6	no	9.813	9.758	EPSD	COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	P21333	FLNA	P31749	AKT1	S2338	V2337I	2337	Missense	proximal	-1	no	9.813	9.798	EPSD	COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	P21333	FLNA	P31749	AKT1	S2338	S2343N	2343	Missense	distal	5	no	9.813	9.778	EPSD	COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	P21333	FLNA	P31749	AKT1	S2372	D2365N	2365	Missense	distal	-7	no	8.250	8.507	EPSD	COSMIC	7.780	Up-regulation
AGC_Akt_AKT1_ST	P21333	FLNA	P31749	AKT1	S2372	C2378S	2378	Missense	distal	6	no	8.250	8.453	EPSD	COSMIC	7.780	Up-regulation
AGC_Akt_AKT1_ST	P21333	FLNA	P31749	AKT1	S2372	S2370N	2370	Missense	proximal	-2	no	8.250	7.564	EPSD	COSMIC	7.780	Loss
AGC_Akt_AKT1_ST	P21333	FLNA	P31749	AKT1	S2523	V2522I	2522	Missense	proximal	-1	no	11.041	11.026	EPSD	COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	P21333	FLNA	P31749	AKT1	S2523	H2528Q	2528	Missense	distal	5	no	11.041	11.064	EPSD	COSMIC	7.780	Up-regulation
AGC_Akt_AKT1_ST	P21333	FLNA	P31749	AKT1	S2523	H2525P	2525	Missense	proximal	2	no	11.041	11.238	EPSD	COSMIC	7.780	Up-regulation
AGC_Akt_AKT1_ST	P21333	FLNA	P31749	AKT1	S2615	Y2618C	2618	Missense	distal	3	no	12.935	12.826	EPSD	COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	P21333	FLNA	P31749	AKT1	S2617	Y2618C	2618	Missense	proximal	1	no	8.044	7.668	EPSD	COSMIC	7.780	Loss
AGC_Akt_AKT1_ST	P21333	FLNA	P31749	AKT1	S2617	K2623N	2623	Missense	distal	6	no	8.044	7.966	EPSD	COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	P30291	WEE1	P31749	AKT1	T257	R253L	253	Missense	distal	-4	no	14.609	13.399	EPSD	COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	P30291	WEE1	P31749	AKT1	T257	R254T	254	Missense	distal	-3	no	14.609	7.587	EPSD	COSMIC	7.780	Loss
AGC_Akt_AKT1_ST	P30291	WEE1	P31749	AKT1	S559	P558S	558	Missense	proximal	-1	no	10.760	10.789	EPSD	COSMIC	7.780	Up-regulation
AGC_Akt_AKT1_ST	P30291	WEE1	P31749	AKT1	S559	R556I	556	Missense	distal	-3	no	10.760	3.679	EPSD	COSMIC	7.780	Loss
AGC_Akt_AKT1_ST	P30291	WEE1	P31749	AKT1	S642	R639H	639	Missense	distal	-3	no	13.451	8.753	PhosphoSitePlus	COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	P30291	WEE1	P31749	AKT1	T644	R639H	639	Missense	distal	-5	no	10.057	6.962	EPSD	COSMIC	7.780	Loss
AGC_Akt_AKT1_ST	P78371	CCT2	P31749	AKT1	T99	G96R	96	Missense	distal	-3	no	2.700	9.456	EPSD	COSMIC	7.780	Gain
AGC_Akt_AKT1_ST	P78371	CCT2	P31749	AKT1	S101	G96R	96	Missense	distal	-5	no	4.769	8.834	EPSD	COSMIC	7.780	Gain
AGC_Akt_AKT1_ST	P78371	CCT2	P31749	AKT1	T134	A136T	136	Missense	proximal	2	no	10.179	10.480	EPSD	COSMIC	7.780	Up-regulation
AGC_Akt_AKT1_ST	P78371	CCT2	P31749	AKT1	S143	G149D	149	Missense	distal	6	no	8.120	8.076	EPSD	COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	P78371	CCT2	P31749	AKT1	S143	S150C	150	Missense	distal	7	no	8.120	7.997	EPSD	COSMIC;GDSC;CCLE	7.780	Down-regulation
AGC_Akt_AKT1_ST	P78371	CCT2	P31749	AKT1	S143	A136T	136	Missense	distal	-7	no	8.120	8.319	EPSD	COSMIC	7.780	Up-regulation
AGC_Akt_AKT1_ST	P78371	CCT2	P31749	AKT1	T379	D384G	384	Missense	distal	5	no	10.191	10.202	EPSD	COSMIC	7.780	Up-regulation
AGC_Akt_AKT1_ST	P41279	MAP3K8	P31749	AKT1	S62	E69D	69	Missense	distal	7	no	12.056	12.013	EPSD	COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	P41279	MAP3K8	P31749	AKT1	S443	R442G	442	Missense	proximal	-1	no	12.799	12.759	EPSD	COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	P41279	MAP3K8	P31749	AKT1	S443	D447G	447	Missense	distal	4	no	12.799	12.748	EPSD	COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	P41279	MAP3K8	P31749	AKT1	S443	R442C	442	Missense	proximal	-1	no	12.799	12.729	EPSD	COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	P41279	MAP3K8	P31749	AKT1	S443	K439T	439	Missense	distal	-4	no	12.799	12.783	EPSD	COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	Q96QB1	DLC1	P31749	AKT1	S354	D353N	353	Missense	proximal	-1	no	14.062	14.092	EPSD	COSMIC	7.780	Up-regulation
AGC_Akt_AKT1_ST	Q96QB1	DLC1	P31749	AKT1	S354	D348E	348	Missense	distal	-6	no	14.062	14.134	EPSD	COSMIC;GDSC;CCLE	7.780	Up-regulation
AGC_Akt_AKT1_ST	Q96QB1	DLC1	P31749	AKT1	S354	S354N	354	Missense	central	0	yes	14.062	0.000	EPSD	COSMIC	7.780	Loss
AGC_Akt_AKT1_ST	Q96QB1	DLC1	P31749	AKT1	T384	G381R	381	Missense	distal	-3	no	5.200	11.956	EPSD	COSMIC	7.780	Gain
AGC_Akt_AKT1_ST	Q96QB1	DLC1	P31749	AKT1	S523	E528G	528	Missense	distal	5	no	10.489	10.458	EPSD	COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	Q96QB1	DLC1	P31749	AKT1	S523	D525N	525	Missense	proximal	2	no	10.489	10.819	EPSD	COSMIC	7.780	Up-regulation
AGC_Akt_AKT1_ST	Q96QB1	DLC1	P31749	AKT1	S523	R522Q	522	Missense	proximal	-1	no	10.489	10.456	EPSD	COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	Q96QB1	DLC1	P31749	AKT1	S523	D529N	529	Missense	distal	6	no	10.489	10.570	EPSD	COSMIC	7.780	Up-regulation
AGC_Akt_AKT1_ST	Q96QB1	DLC1	P31749	AKT1	S548	R546K	546	Missense	proximal	-2	no	8.566	9.005	EPSD	COSMIC	7.780	Up-regulation
AGC_Akt_AKT1_ST	Q96QB1	DLC1	P31749	AKT1	S548	E552D	552	Missense	distal	4	no	8.566	8.712	EPSD	COSMIC	7.780	Up-regulation
AGC_Akt_AKT1_ST	Q96QB1	DLC1	P31749	AKT1	S548	F553I	553	Missense	distal	5	no	8.566	8.541	EPSD	COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	Q96QB1	DLC1	P31749	AKT1	S548	R542K	542	Missense	distal	-6	no	8.566	8.551	EPSD	COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	Q96QB1	DLC1	P31749	AKT1	S548	E552K	552	Missense	distal	4	no	8.566	8.465	EPSD	COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	Q96QB1	DLC1	P31749	AKT1	S548	S544G	544	Missense	distal	-4	no	8.566	7.837	EPSD	COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	Q96QB1	DLC1	P31749	AKT1	S548	D554N	554	Missense	distal	6	no	8.566	8.647	EPSD	COSMIC	7.780	Up-regulation
AGC_Akt_AKT1_ST	Q96QB1	DLC1	P31749	AKT1	S598	S599R	599	Missense	proximal	1	no	10.137	10.282	EPSD	COSMIC	7.780	Up-regulation
AGC_Akt_AKT1_ST	Q96QB1	DLC1	P31749	AKT1	S598	L603I	603	Missense	distal	5	no	10.137	10.107	EPSD	COSMIC;CCLE	7.780	Down-regulation
AGC_Akt_AKT1_ST	Q96QB1	DLC1	P31749	AKT1	S598	S598R	598	Missense	central	0	yes	10.137	0.000	EPSD	COSMIC	7.780	Loss
AGC_Akt_AKT1_ST	Q96QB1	DLC1	P31749	AKT1	S598	S605L	605	Missense	distal	7	no	10.137	10.071	EPSD	COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	Q96QB1	DLC1	P31749	AKT1	T600	S599R	599	Missense	proximal	-1	no	8.833	8.843	EPSD	COSMIC	7.780	Up-regulation
AGC_Akt_AKT1_ST	Q96QB1	DLC1	P31749	AKT1	T600	A607T	607	Missense	distal	7	no	8.833	8.893	EPSD	COSMIC	7.780	Up-regulation
AGC_Akt_AKT1_ST	Q96QB1	DLC1	P31749	AKT1	T600	L603I	603	Missense	distal	3	no	8.833	8.799	EPSD	COSMIC;CCLE	7.780	Down-regulation
AGC_Akt_AKT1_ST	Q96QB1	DLC1	P31749	AKT1	T600	S598R	598	Missense	proximal	-2	no	8.833	8.644	EPSD	COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	Q96QB1	DLC1	P31749	AKT1	T600	S605L	605	Missense	distal	5	no	8.833	8.766	EPSD	COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	Q96QB1	DLC1	P31749	AKT1	T600	H606Y	606	Missense	distal	6	no	8.833	8.865	EPSD	COSMIC	7.780	Up-regulation
AGC_Akt_AKT1_ST	Q96QB1	DLC1	P31749	AKT1	S602	S599R	599	Missense	distal	-3	no	3.268	11.044	EPSD	COSMIC	7.780	Gain
AGC_Akt_AKT1_ST	Q96QB1	DLC1	P31749	AKT1	S620	S626F	626	Missense	distal	6	no	11.667	11.548	EPSD	COSMIC;GDSC;CCLE	7.780	Down-regulation
AGC_Akt_AKT1_ST	Q96QB1	DLC1	P31749	AKT1	S620	R617W	617	Missense	distal	-3	no	11.667	2.727	EPSD	COSMIC	7.780	Loss
AGC_Akt_AKT1_ST	Q96QB1	DLC1	P31749	AKT1	S620	V621I	621	Missense	proximal	1	no	11.667	11.420	EPSD	COSMIC;GDSC;CCLE	7.780	Down-regulation
AGC_Akt_AKT1_ST	Q96QB1	DLC1	P31749	AKT1	S666	T664M	664	Missense	proximal	-2	no	9.369	8.596	EPSD	COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	Q96QB1	DLC1	P31749	AKT1	S666	R665C	665	Missense	proximal	-1	no	9.369	9.299	EPSD	COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	Q96QB1	DLC1	P31749	AKT1	S666	S666N	666	Missense	central	0	yes	9.369	0.000	EPSD	COSMIC	7.780	Loss
AGC_Akt_AKT1_ST	Q96QB1	DLC1	P31749	AKT1	S666	R670W	670	Missense	distal	4	no	9.369	9.616	EPSD	COSMIC	7.780	Up-regulation
AGC_Akt_AKT1_ST	Q96QB1	DLC1	P31749	AKT1	S666	R670Q	670	Missense	distal	4	no	9.369	9.492	EPSD	COSMIC	7.780	Up-regulation
AGC_Akt_AKT1_ST	Q96QB1	DLC1	P31749	AKT1	S673	S666N	666	Missense	distal	-7	no	11.401	11.286	EPSD	COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	Q96QB1	DLC1	P31749	AKT1	S673	R670W	670	Missense	distal	-3	no	11.401	2.460	EPSD	COSMIC	7.780	Loss
AGC_Akt_AKT1_ST	Q96QB1	DLC1	P31749	AKT1	S673	R670Q	670	Missense	distal	-3	no	11.401	4.189	EPSD	COSMIC	7.780	Loss
AGC_Akt_AKT1_ST	Q96QB1	DLC1	P31749	AKT1	S733	M728V	728	Missense	distal	-5	no	10.316	10.524	EPSD	COSMIC	7.780	Up-regulation
AGC_Akt_AKT1_ST	Q96QB1	DLC1	P31749	AKT1	S733	T738M	738	Missense	distal	5	no	10.316	10.259	EPSD	COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	Q96QB1	DLC1	P31749	AKT1	S733	R730Q	730	Missense	distal	-3	no	10.316	3.105	EPSD	COSMIC;GDSC	7.780	Loss
AGC_Akt_AKT1_ST	Q96QB1	DLC1	P31749	AKT1	S733	R732T	732	Missense	proximal	-1	no	10.316	10.312	EPSD	COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	Q96QB1	DLC1	P31749	AKT1	S733	S733F	733	Missense	central	0	yes	10.316	0.000	EPSD	COSMIC	7.780	Loss
AGC_Akt_AKT1_ST	Q96QB1	DLC1	P31749	AKT1	S735	S741T	741	Missense	distal	6	no	16.477	16.498	PhosphoSitePlus;EPSD	COSMIC	7.780	Up-regulation
AGC_Akt_AKT1_ST	Q96QB1	DLC1	P31749	AKT1	S735	M728V	728	Missense	distal	-7	no	16.477	16.415	PhosphoSitePlus;EPSD	COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	Q96QB1	DLC1	P31749	AKT1	S735	T738M	738	Missense	distal	3	no	16.477	16.393	PhosphoSitePlus;EPSD	COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	Q96QB1	DLC1	P31749	AKT1	S735	R730Q	730	Missense	distal	-5	no	16.477	12.249	PhosphoSitePlus;EPSD	COSMIC;GDSC	7.780	Down-regulation
AGC_Akt_AKT1_ST	Q96QB1	DLC1	P31749	AKT1	S735	R732T	732	Missense	distal	-3	no	16.477	9.455	PhosphoSitePlus;EPSD	COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	Q96QB1	DLC1	P31749	AKT1	S735	S733F	733	Missense	proximal	-2	no	16.477	15.610	PhosphoSitePlus;EPSD	COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	Q96QB1	DLC1	P31749	AKT1	S737	S744T	744	Missense	distal	7	no	10.749	10.759	EPSD	COSMIC	7.780	Up-regulation
AGC_Akt_AKT1_ST	Q96QB1	DLC1	P31749	AKT1	S737	S741T	741	Missense	distal	4	no	10.749	10.744	EPSD	COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	Q96QB1	DLC1	P31749	AKT1	S737	T738M	738	Missense	proximal	1	no	10.749	10.493	EPSD	COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	Q96QB1	DLC1	P31749	AKT1	S737	R730Q	730	Missense	distal	-7	no	10.749	10.555	EPSD	COSMIC;GDSC	7.780	Down-regulation
AGC_Akt_AKT1_ST	Q96QB1	DLC1	P31749	AKT1	S737	R732T	732	Missense	distal	-5	no	10.749	7.019	EPSD	COSMIC	7.780	Loss
AGC_Akt_AKT1_ST	Q96QB1	DLC1	P31749	AKT1	S737	S733F	733	Missense	distal	-4	no	10.749	9.581	EPSD	COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	Q96QB1	DLC1	P31749	AKT1	S764	S757N	757	Missense	distal	-7	no	12.778	12.664	EPSD	COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	Q96QB1	DLC1	P31749	AKT1	S764	R763Q	763	Missense	proximal	-1	no	12.778	12.746	EPSD	COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	Q96QB1	DLC1	P31749	AKT1	S764	T762S	762	Missense	proximal	-2	no	12.778	12.844	EPSD	COSMIC	7.780	Up-regulation
AGC_Akt_AKT1_ST	Q96QB1	DLC1	P31749	AKT1	S764	R771Q	771	Missense	distal	7	no	12.778	12.722	EPSD	COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	Q96QB1	DLC1	P31749	AKT1	S764	R763W	763	Missense	proximal	-1	no	12.778	12.717	EPSD	COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	Q96QB1	DLC1	P31749	AKT1	S764	A767G	767	Missense	distal	3	no	12.778	12.745	EPSD	COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	Q96QB1	DLC1	P31749	AKT1	S766	R763Q	763	Missense	distal	-3	no	15.353	8.142	EPSD;PhosphoSitePlus	COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	Q96QB1	DLC1	P31749	AKT1	S766	T762S	762	Missense	distal	-4	no	15.353	15.297	EPSD;PhosphoSitePlus	COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	Q96QB1	DLC1	P31749	AKT1	S766	R771Q	771	Missense	distal	5	no	15.353	15.302	EPSD;PhosphoSitePlus	COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	Q96QB1	DLC1	P31749	AKT1	S766	R763W	763	Missense	distal	-3	no	15.353	6.413	EPSD;PhosphoSitePlus	COSMIC	7.780	Loss
AGC_Akt_AKT1_ST	Q96QB1	DLC1	P31749	AKT1	S766	A767G	767	Missense	proximal	1	no	15.353	15.122	EPSD;PhosphoSitePlus	COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	Q96QB1	DLC1	P31749	AKT1	S830	N833D	833	Missense	distal	3	no	7.909	7.853	EPSD	COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	Q96QB1	DLC1	P31749	AKT1	S830	S828F	828	Missense	proximal	-2	no	7.909	7.042	EPSD	COSMIC	7.780	Loss
AGC_Akt_AKT1_ST	Q96QB1	DLC1	P31749	AKT1	S830	T823I	823	Missense	distal	-7	no	7.909	7.486	EPSD	COSMIC	7.780	Loss
AGC_Akt_AKT1_ST	Q96QB1	DLC1	P31749	AKT1	S842	G845S	845	Missense	distal	3	no	9.815	9.906	EPSD	COSMIC	7.780	Up-regulation
AGC_Akt_AKT1_ST	Q96QB1	DLC1	P31749	AKT1	S842	T840M	840	Missense	proximal	-2	no	9.815	9.042	EPSD	COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	Q96QB1	DLC1	P31749	AKT1	S842	P846F	846	Missense	distal	4	no	9.815	9.855	EPSD	COSMIC	7.780	Up-regulation
AGC_Akt_AKT1_ST	Q96QB1	DLC1	P31749	AKT1	S856	R853M	853	Missense	distal	-3	no	11.907	4.402	EPSD	COSMIC	7.780	Loss
AGC_Akt_AKT1_ST	Q96QB1	DLC1	P31749	AKT1	S856	N855D	855	Missense	proximal	-1	no	11.907	11.877	EPSD	COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	Q96QB1	DLC1	P31749	AKT1	S856	S859G	859	Missense	distal	3	no	11.907	11.817	EPSD	COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	Q96QB1	DLC1	P31749	AKT1	S856	E862K	862	Missense	distal	6	no	11.907	11.977	EPSD	COSMIC	7.780	Up-regulation
AGC_Akt_AKT1_ST	Q96QB1	DLC1	P31749	AKT1	S857	R853M	853	Missense	distal	-4	no	9.035	8.040	EPSD	COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	Q96QB1	DLC1	P31749	AKT1	S857	N855D	855	Missense	proximal	-2	no	9.035	8.328	EPSD	COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	Q96QB1	DLC1	P31749	AKT1	S857	S859G	859	Missense	proximal	2	no	9.035	8.703	EPSD	COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	Q96QB1	DLC1	P31749	AKT1	S857	E862K	862	Missense	distal	5	no	9.035	9.069	EPSD	COSMIC	7.780	Up-regulation
AGC_Akt_AKT1_ST	Q96QB1	DLC1	P31749	AKT1	S868	R875H	875	Missense	distal	7	no	12.939	12.867	EPSD	COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	Q96QB1	DLC1	P31749	AKT1	S868	E862K	862	Missense	distal	-6	no	12.939	13.006	EPSD	COSMIC	7.780	Up-regulation
AGC_Akt_AKT1_ST	Q96QB1	DLC1	P31749	AKT1	S869	R875H	875	Missense	distal	6	no	13.477	13.358	EPSD	COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	Q96QB1	DLC1	P31749	AKT1	S869	E862K	862	Missense	distal	-7	no	13.477	13.670	EPSD	COSMIC	7.780	Up-regulation
AGC_Akt_AKT1_ST	Q96QB1	DLC1	P31749	AKT1	S870	R875H	875	Missense	distal	5	no	10.064	9.990	EPSD	COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	Q96QB1	DLC1	P31749	AKT1	S945	P942R	942	Missense	distal	-3	no	1.775	8.415	EPSD	COSMIC	7.780	Gain
AGC_Akt_AKT1_ST	Q96QB1	DLC1	P31749	AKT1	S986	G989V	989	Missense	distal	3	no	12.650	12.651	EPSD	COSMIC	7.780	Up-regulation
AGC_Akt_AKT1_ST	Q96QB1	DLC1	P31749	AKT1	S986	R983K	983	Missense	distal	-3	no	12.650	8.130	EPSD	COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	Q96QB1	DLC1	P31749	AKT1	S986	G987A	987	Missense	proximal	1	no	12.650	12.881	EPSD	COSMIC	7.780	Up-regulation
AGC_Akt_AKT1_ST	Q96QB1	DLC1	P31749	AKT1	S986	E979K	979	Missense	distal	-7	no	12.650	12.843	EPSD	COSMIC	7.780	Up-regulation
AGC_Akt_AKT1_ST	Q96QB1	DLC1	P31749	AKT1	S1004	H1009Y	1009	Missense	distal	5	no	15.281	15.304	EPSD;PhosphoSitePlus	COSMIC	7.780	Up-regulation
AGC_Akt_AKT1_ST	Q96QB1	DLC1	P31749	AKT1	S1004	R1001Q	1001	Missense	distal	-3	no	15.281	8.069	EPSD;PhosphoSitePlus	COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	Q96QB1	DLC1	P31749	AKT1	S1004	S1004I	1004	Missense	central	0	yes	15.281	0.000	EPSD;PhosphoSitePlus	COSMIC	7.780	Loss
AGC_Akt_AKT1_ST	Q96QB1	DLC1	P31749	AKT1	S1015	C1022F	1022	Missense	distal	7	no	7.777	7.825	EPSD	COSMIC	7.780	Gain
AGC_Akt_AKT1_ST	Q96QB1	DLC1	P31749	AKT1	S1015	H1009Y	1009	Missense	distal	-6	no	7.777	7.802	EPSD	COSMIC	7.780	Gain
AGC_Akt_AKT1_ST	Q96QB1	DLC1	P31749	AKT1	S1167	N1164K	1164	Missense	distal	-3	no	5.033	7.990	EPSD	COSMIC	7.780	Gain
AGC_Akt_AKT1_ST	Q96QB1	DLC1	P31749	AKT1	S1244	M1249I	1249	Missense	distal	5	no	12.859	12.819	EPSD	COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	Q96QB1	DLC1	P31749	AKT1	S1254	D1259Y	1259	Missense	distal	5	no	11.719	11.751	EPSD	COSMIC	7.780	Up-regulation
AGC_Akt_AKT1_ST	Q96QB1	DLC1	P31749	AKT1	S1254	M1249I	1249	Missense	distal	-5	no	11.719	11.674	EPSD	COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	Q96QB1	DLC1	P31749	AKT1	S1296	E1289K	1289	Missense	distal	-7	no	7.618	7.811	EPSD	COSMIC	7.780	Gain
AGC_Akt_AKT1_ST	Q96QB1	DLC1	P31749	AKT1	S1296	R1294S	1294	Missense	proximal	-2	no	7.618	7.807	EPSD	COSMIC	7.780	Gain
AGC_Akt_AKT1_ST	Q96QB1	DLC1	P31749	AKT1	T1298	N1295D	1295	Missense	distal	-3	no	6.332	7.858	EPSD	COSMIC	7.780	Gain
AGC_Akt_AKT1_ST	Q96QB1	DLC1	P31749	AKT1	S1516	F1515L	1515	Missense	proximal	-1	no	9.256	9.263	EPSD	COSMIC	7.780	Up-regulation
AGC_Akt_AKT1_ST	P26373	RPL13	P31749	AKT1	S77	V70A	70	Missense	distal	-7	no	10.529	10.657	EPSD	COSMIC	7.780	Up-regulation
AGC_Akt_AKT1_ST	P26373	RPL13	P31749	AKT1	S77	A84G	84	Missense	distal	7	no	10.529	10.506	EPSD	COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	P26373	RPL13	P31749	AKT1	S77	E80K	80	Missense	distal	3	no	10.529	10.572	EPSD	COSMIC	7.780	Up-regulation
AGC_Akt_AKT1_ST	P26373	RPL13	P31749	AKT1	S97	R92W	92	Missense	distal	-5	no	9.562	4.042	EPSD	COSMIC	7.780	Loss
AGC_Akt_AKT1_ST	P26373	RPL13	P31749	AKT1	S106	A112T	112	Missense	distal	6	no	15.515	15.617	PhosphoSitePlus	COSMIC	7.780	Up-regulation
AGC_Akt_AKT1_ST	P26373	RPL13	P31749	AKT1	S132	S139N	139	Missense	distal	7	no	11.763	11.728	EPSD	COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	P26373	RPL13	P31749	AKT1	S132	K135N	135	Missense	distal	3	no	11.763	11.705	EPSD	COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	P26373	RPL13	P31749	AKT1	S132	P128L	128	Missense	distal	-4	no	11.763	11.376	EPSD	COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	P26373	RPL13	P31749	AKT1	T170	R167L	167	Missense	distal	-3	no	11.384	4.390	EPSD	COSMIC;CCLE	7.780	Loss
AGC_Akt_AKT1_ST	P26373	RPL13	P31749	AKT1	T170	N175S	175	Missense	distal	5	no	11.384	11.418	EPSD	COSMIC	7.780	Up-regulation
AGC_Akt_AKT1_ST	P55072	VCP	P31749	AKT1	T56	K62T	62	Missense	distal	6	no	10.933	10.943	EPSD	COSMIC	7.780	Up-regulation
AGC_Akt_AKT1_ST	P55072	VCP	P31749	AKT1	S352	I353T	353	Missense	proximal	1	no	12.816	13.258	PhosphoSitePlus;EPSD	COSMIC	7.780	Up-regulation
AGC_Akt_AKT1_ST	P55072	VCP	P31749	AKT1	S352	I353N	353	Missense	proximal	1	no	12.816	12.976	PhosphoSitePlus;EPSD	COSMIC	7.780	Up-regulation
AGC_Akt_AKT1_ST	P55072	VCP	P31749	AKT1	S705	S702F	702	Missense	distal	-3	no	8.293	10.475	EPSD	COSMIC	7.780	Up-regulation
AGC_Akt_AKT1_ST	P55072	VCP	P31749	AKT1	S746	A743V	743	Missense	distal	-3	no	11.046	10.484	EPSD;PhosphoSitePlus	COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	P55072	VCP	P31749	AKT1	S746	R753W	753	Missense	distal	7	no	11.046	10.948	EPSD;PhosphoSitePlus	COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	P55072	VCP	P31749	AKT1	S748	A743V	743	Missense	distal	-5	no	12.791	12.331	EPSD;PhosphoSitePlus	COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	P55072	VCP	P31749	AKT1	S748	R753W	753	Missense	distal	5	no	12.791	12.697	EPSD;PhosphoSitePlus	COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	P55072	VCP	P31749	AKT1	S775	P774S	774	Missense	proximal	-1	no	9.150	9.179	EPSD	COSMIC	7.780	Up-regulation
AGC_Akt_AKT1_ST	P55072	VCP	P31749	AKT1	S775	G769A	769	Missense	distal	-6	no	9.150	9.175	EPSD	COSMIC	7.780	Up-regulation
AGC_Akt_AKT1_ST	Q92793	CREBBP	P31749	AKT1	S18	F22L	22	Missense	distal	4	no	10.959	10.951	EPSD	COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	Q92793	CREBBP	P31749	AKT1	S18	P12H	12	Missense	distal	-6	no	10.959	10.938	EPSD	COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	Q92793	CREBBP	P31749	AKT1	S18	P20T	20	Missense	proximal	2	no	10.959	11.220	EPSD	COSMIC	7.780	Up-regulation
AGC_Akt_AKT1_ST	Q92793	CREBBP	P31749	AKT1	S18	G21D	21	Missense	distal	3	no	10.959	10.938	EPSD	COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	Q92793	CREBBP	P31749	AKT1	S19	F22L	22	Missense	distal	3	no	12.442	12.443	EPSD	COSMIC	7.780	Up-regulation
AGC_Akt_AKT1_ST	Q92793	CREBBP	P31749	AKT1	S19	P12H	12	Missense	distal	-7	no	12.442	12.391	EPSD	COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	Q92793	CREBBP	P31749	AKT1	S19	P20T	20	Missense	proximal	1	no	12.442	12.791	EPSD	COSMIC	7.780	Up-regulation
AGC_Akt_AKT1_ST	Q92793	CREBBP	P31749	AKT1	S19	G21D	21	Missense	proximal	2	no	12.442	12.175	EPSD	COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	Q92793	CREBBP	P31749	AKT1	S78	S78C	78	Missense	central	0	yes	10.808	0.000	EPSD	COSMIC	7.780	Loss
AGC_Akt_AKT1_ST	Q92793	CREBBP	P31749	AKT1	S78	L74V	74	Missense	distal	-4	no	10.808	10.838	EPSD	COSMIC	7.780	Up-regulation
AGC_Akt_AKT1_ST	Q92793	CREBBP	P31749	AKT1	S78	N83T	83	Missense	distal	5	no	10.808	10.843	EPSD	COSMIC;GDSC;CCLE	7.780	Up-regulation
AGC_Akt_AKT1_ST	Q92793	CREBBP	P31749	AKT1	S80	S78C	78	Missense	proximal	-2	no	9.208	7.556	EPSD	COSMIC	7.780	Loss
AGC_Akt_AKT1_ST	Q92793	CREBBP	P31749	AKT1	S80	L74V	74	Missense	distal	-6	no	9.208	9.184	EPSD	COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	Q92793	CREBBP	P31749	AKT1	S80	N83T	83	Missense	distal	3	no	9.208	9.264	EPSD	COSMIC;GDSC;CCLE	7.780	Up-regulation
AGC_Akt_AKT1_ST	Q92793	CREBBP	P31749	AKT1	S381	M388R	388	Missense	distal	7	no	11.446	11.512	EPSD	COSMIC	7.780	Up-regulation
AGC_Akt_AKT1_ST	Q92793	CREBBP	P31749	AKT1	S381	R378Q	378	Missense	distal	-3	no	11.446	4.235	EPSD	COSMIC	7.780	Loss
AGC_Akt_AKT1_ST	Q92793	CREBBP	P31749	AKT1	S381	N374I	374	Missense	distal	-7	no	11.446	11.188	EPSD	COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	Q92793	CREBBP	P31749	AKT1	S745	R742P	742	Missense	distal	-3	no	12.849	6.209	EPSD	COSMIC	7.780	Loss
AGC_Akt_AKT1_ST	Q92793	CREBBP	P31749	AKT1	S745	M747V	747	Missense	proximal	2	no	12.849	12.728	EPSD	COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	Q92793	CREBBP	P31749	AKT1	S745	V751A	751	Missense	distal	6	no	12.849	12.881	EPSD	COSMIC	7.780	Up-regulation
AGC_Akt_AKT1_ST	Q92793	CREBBP	P31749	AKT1	S745	R742L	742	Missense	distal	-3	no	12.849	5.855	EPSD	COSMIC	7.780	Loss
AGC_Akt_AKT1_ST	Q92793	CREBBP	P31749	AKT1	T974	V978M	978	Missense	distal	4	no	10.364	10.348	EPSD	COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	Q92793	CREBBP	P31749	AKT1	T974	P975S	975	Missense	proximal	1	no	10.364	10.519	EPSD	COSMIC	7.780	Up-regulation
AGC_Akt_AKT1_ST	Q92793	CREBBP	P31749	AKT1	T974	D969H	969	Missense	distal	-5	no	10.364	11.315	EPSD	COSMIC	7.780	Up-regulation
AGC_Akt_AKT1_ST	Q92793	CREBBP	P31749	AKT1	T974	A981T	981	Missense	distal	7	no	10.364	10.425	EPSD	COSMIC;GDSC	7.780	Up-regulation
AGC_Akt_AKT1_ST	Q92793	CREBBP	P31749	AKT1	T974	S977L	977	Missense	distal	3	no	10.364	10.267	EPSD	COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	Q92793	CREBBP	P31749	AKT1	T974	S967N	967	Missense	distal	-7	no	10.364	10.250	EPSD	COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	Q92793	CREBBP	P31749	AKT1	T974	S977P	977	Missense	distal	3	no	10.364	10.283	EPSD	COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	Q92793	CREBBP	P31749	AKT1	T974	N970I	970	Missense	distal	-4	no	10.364	9.549	EPSD	COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	Q92793	CREBBP	P31749	AKT1	S976	V978M	978	Missense	proximal	2	no	8.736	8.857	EPSD	COSMIC	7.780	Up-regulation
AGC_Akt_AKT1_ST	Q92793	CREBBP	P31749	AKT1	S976	P975S	975	Missense	proximal	-1	no	8.736	8.765	EPSD	COSMIC	7.780	Up-regulation
AGC_Akt_AKT1_ST	Q92793	CREBBP	P31749	AKT1	S976	D969H	969	Missense	distal	-7	no	8.736	8.862	EPSD	COSMIC	7.780	Up-regulation
AGC_Akt_AKT1_ST	Q92793	CREBBP	P31749	AKT1	S976	A981T	981	Missense	distal	5	no	8.736	8.787	EPSD	COSMIC;GDSC	7.780	Up-regulation
AGC_Akt_AKT1_ST	Q92793	CREBBP	P31749	AKT1	S976	S977L	977	Missense	proximal	1	no	8.736	8.834	EPSD	COSMIC	7.780	Up-regulation
AGC_Akt_AKT1_ST	Q92793	CREBBP	P31749	AKT1	S976	S977P	977	Missense	proximal	1	no	8.736	8.580	EPSD	COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	Q92793	CREBBP	P31749	AKT1	S976	N970I	970	Missense	distal	-6	no	8.736	8.662	EPSD	COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	Q92793	CREBBP	P31749	AKT1	S976	E982G	982	Missense	distal	6	no	8.736	8.689	EPSD	COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	Q92793	CREBBP	P31749	AKT1	S976	E982V	982	Missense	distal	6	no	8.736	8.681	EPSD	COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	Q92793	CREBBP	P31749	AKT1	S1072	G1069R	1069	Missense	distal	-3	no	5.633	12.389	EPSD	COSMIC	7.780	Gain
AGC_Akt_AKT1_ST	Q92793	CREBBP	P31749	AKT1	S1074	G1069R	1069	Missense	distal	-5	no	6.973	11.037	EPSD	COSMIC	7.780	Gain
AGC_Akt_AKT1_ST	Q92793	CREBBP	P31749	AKT1	S1108	P1110L	1110	Missense	proximal	2	no	9.863	9.654	EPSD	COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	Q92793	CREBBP	P31749	AKT1	S1108	R1103L	1103	Missense	distal	-5	no	9.863	5.737	EPSD	COSMIC	7.780	Loss
AGC_Akt_AKT1_ST	Q92793	CREBBP	P31749	AKT1	S1108	R1112W	1112	Missense	distal	4	no	9.863	10.110	EPSD	COSMIC	7.780	Up-regulation
AGC_Akt_AKT1_ST	Q92793	CREBBP	P31749	AKT1	S1108	P1114S	1114	Missense	distal	6	no	9.863	9.957	EPSD	COSMIC	7.780	Up-regulation
AGC_Akt_AKT1_ST	Q92793	CREBBP	P31749	AKT1	S1108	V1115I	1115	Missense	distal	7	no	9.863	9.821	EPSD	COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	Q92793	CREBBP	P31749	AKT1	S1108	Q1113H	1113	Missense	distal	5	no	9.863	9.840	EPSD	COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	Q92793	CREBBP	P31749	AKT1	S1108	S1108L	1108	Missense	central	0	yes	9.863	0.000	EPSD	COSMIC;GDSC;CCLE	7.780	Loss
AGC_Akt_AKT1_ST	Q92793	CREBBP	P31749	AKT1	S1108	Y1102C	1102	Missense	distal	-6	no	9.863	9.776	EPSD	COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	Q92793	CREBBP	P31749	AKT1	T1274	V1281I	1281	Missense	distal	7	no	8.300	8.257	EPSD	COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	Q92793	CREBBP	P31749	AKT1	T1274	K1269N	1269	Missense	distal	-5	no	8.300	6.213	EPSD	COSMIC	7.780	Loss
AGC_Akt_AKT1_ST	Q92793	CREBBP	P31749	AKT1	T1274	K1271R	1271	Missense	distal	-3	no	8.300	12.820	EPSD	COSMIC	7.780	Up-regulation
AGC_Akt_AKT1_ST	Q92793	CREBBP	P31749	AKT1	T1274	P1277A	1277	Missense	distal	3	no	8.300	8.324	EPSD	COSMIC	7.780	Up-regulation
AGC_Akt_AKT1_ST	Q92793	CREBBP	P31749	AKT1	T1274	D1273N	1273	Missense	proximal	-1	no	8.300	8.330	EPSD	COSMIC	7.780	Up-regulation
AGC_Akt_AKT1_ST	Q92793	CREBBP	P31749	AKT1	T1274	D1276H	1276	Missense	proximal	2	no	8.300	8.366	EPSD	COSMIC	7.780	Up-regulation
AGC_Akt_AKT1_ST	Q92793	CREBBP	P31749	AKT1	T1274	D1276E	1276	Missense	proximal	2	no	8.300	8.710	EPSD	COSMIC	7.780	Up-regulation
AGC_Akt_AKT1_ST	Q92793	CREBBP	P31749	AKT1	S1568	A1571D	1571	Missense	distal	3	no	11.882	11.828	EPSD	COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	Q92793	CREBBP	P31749	AKT1	S1568	K1564E	1564	Missense	distal	-4	no	11.882	11.298	EPSD	COSMIC;GDSC;CCLE	7.780	Down-regulation
AGC_Akt_AKT1_ST	Q92793	CREBBP	P31749	AKT1	S1568	R1563S	1563	Missense	distal	-5	no	11.882	7.412	EPSD	COSMIC;CCLE	7.780	Loss
AGC_Akt_AKT1_ST	Q92793	CREBBP	P31749	AKT1	S1609	K1606R	1606	Missense	distal	-3	no	7.645	12.165	EPSD	COSMIC	7.780	Gain
AGC_Akt_AKT1_ST	Q92793	CREBBP	P31749	AKT1	S1680	H1675R	1675	Missense	distal	-5	no	5.581	8.676	EPSD	COSMIC	7.780	Gain
AGC_Akt_AKT1_ST	Q92793	CREBBP	P31749	AKT1	S1761	P1759T	1759	Missense	proximal	-2	no	7.164	7.922	EPSD	COSMIC	7.780	Gain
AGC_Akt_AKT1_ST	Q92793	CREBBP	P31749	AKT1	S1761	Q1756R	1756	Missense	distal	-5	no	7.164	11.391	EPSD	COSMIC	7.780	Gain
AGC_Akt_AKT1_ST	Q92793	CREBBP	P31749	AKT1	S1767	Q1765L	1765	Missense	proximal	-2	no	7.818	7.662	EPSD	COSMIC	7.780	Loss
AGC_Akt_AKT1_ST	Q92793	CREBBP	P31749	AKT1	S1767	Q1765R	1765	Missense	proximal	-2	no	7.818	8.330	EPSD	COSMIC	7.780	Up-regulation
AGC_Akt_AKT1_ST	Q92793	CREBBP	P31749	AKT1	S1771	Q1765R	1765	Missense	distal	-6	no	12.661	12.746	EPSD	COSMIC	7.780	Up-regulation
AGC_Akt_AKT1_ST	Q92793	CREBBP	P31749	AKT1	S1791	C1795R	1795	Missense	distal	4	no	10.203	9.869	EPSD	COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	Q92793	CREBBP	P31749	AKT1	S1791	N1789K	1789	Missense	proximal	-2	no	10.203	11.140	EPSD	COSMIC	7.780	Up-regulation
AGC_Akt_AKT1_ST	Q92793	CREBBP	P31749	AKT1	S1791	Q1784H	1784	Missense	distal	-7	no	10.203	10.096	EPSD	COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	Q92793	CREBBP	P31749	AKT1	S1791	M1798I	1798	Missense	distal	7	no	10.203	10.165	EPSD	COSMIC;GDSC;CCLE	7.780	Down-regulation
AGC_Akt_AKT1_ST	Q92793	CREBBP	P31749	AKT1	S1791	S1791P	1791	Missense	central	0	yes	10.203	0.000	EPSD	COSMIC	7.780	Loss
AGC_Akt_AKT1_ST	Q92793	CREBBP	P31749	AKT1	T1871	R1866C	1866	Missense	distal	-5	no	15.103	11.026	PhosphoSitePlus	COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	Q92793	CREBBP	P31749	AKT1	T1871	R1866L	1866	Missense	distal	-5	no	15.103	10.976	PhosphoSitePlus	COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	Q92793	CREBBP	P31749	AKT1	T1871	R1868L	1868	Missense	distal	-3	no	15.103	8.109	PhosphoSitePlus	COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	Q92793	CREBBP	P31749	AKT1	T1871	T1874I	1874	Missense	distal	3	no	15.103	14.973	PhosphoSitePlus	COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	Q92793	CREBBP	P31749	AKT1	T1871	A1870P	1870	Missense	proximal	-1	no	15.103	15.094	PhosphoSitePlus	COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	Q92793	CREBBP	P31749	AKT1	T1931	R1926Q	1926	Missense	distal	-5	no	8.972	4.745	EPSD	COSMIC	7.780	Loss
AGC_Akt_AKT1_ST	Q92793	CREBBP	P31749	AKT1	T1931	P1938H	1938	Missense	distal	7	no	8.972	8.966	EPSD	COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	Q92793	CREBBP	P31749	AKT1	T1931	T1932M	1932	Missense	proximal	1	no	8.972	8.716	EPSD	COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	Q92793	CREBBP	P31749	AKT1	T1931	R1926W	1926	Missense	distal	-5	no	8.972	3.452	EPSD	COSMIC	7.780	Loss
AGC_Akt_AKT1_ST	Q92793	CREBBP	P31749	AKT1	T1931	Q1928H	1928	Missense	distal	-3	no	8.972	11.485	EPSD	COSMIC	7.780	Up-regulation
AGC_Akt_AKT1_ST	Q92793	CREBBP	P31749	AKT1	T1990	R1985L	1985	Missense	distal	-5	no	8.260	4.134	EPSD	COSMIC	7.780	Loss
AGC_Akt_AKT1_ST	Q92793	CREBBP	P31749	AKT1	T1990	P1997L	1997	Missense	distal	7	no	8.260	8.252	EPSD	COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	Q92793	CREBBP	P31749	AKT1	T1990	P1991L	1991	Missense	proximal	1	no	8.260	8.514	EPSD	COSMIC	7.780	Up-regulation
AGC_Akt_AKT1_ST	Q92793	CREBBP	P31749	AKT1	T1990	R1985H	1985	Missense	distal	-5	no	8.260	5.165	EPSD	COSMIC	7.780	Loss
AGC_Akt_AKT1_ST	Q92793	CREBBP	P31749	AKT1	T1990	A1996V	1996	Missense	distal	6	no	8.260	8.229	EPSD	COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	Q92793	CREBBP	P31749	AKT1	S2063	V2056M	2056	Missense	distal	-7	no	12.488	12.550	EPSD	COSMIC	7.780	Up-regulation
AGC_Akt_AKT1_ST	Q92793	CREBBP	P31749	AKT1	S2063	S2065N	2065	Missense	proximal	2	no	12.488	12.219	EPSD	COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	Q92793	CREBBP	P31749	AKT1	S2065	S2065N	2065	Missense	central	0	yes	10.199	0.000	EPSD	COSMIC	7.780	Loss
AGC_Akt_AKT1_ST	Q92793	CREBBP	P31749	AKT1	S2356	P2358S	2358	Missense	proximal	2	no	11.114	11.450	EPSD	COSMIC	7.780	Up-regulation
AGC_Akt_AKT1_ST	Q92793	CREBBP	P31749	AKT1	S2356	P2352L	2352	Missense	distal	-4	no	11.114	10.726	EPSD	COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	Q92793	CREBBP	P31749	AKT1	S2356	P2363L	2363	Missense	distal	7	no	11.114	11.106	EPSD	COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	Q92793	CREBBP	P31749	AKT1	S2356	S2361F	2361	Missense	distal	5	no	11.114	11.041	EPSD	COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	Q92793	CREBBP	P31749	AKT1	S2356	S2356P	2356	Missense	central	0	yes	11.114	0.000	EPSD	COSMIC	7.780	Loss
AGC_Akt_AKT1_ST	Q92793	CREBBP	P31749	AKT1	S2356	R2353W	2353	Missense	distal	-3	no	11.114	2.173	EPSD	COSMIC	7.780	Loss
AGC_Akt_AKT1_ST	Q92793	CREBBP	P31749	AKT1	S2422	P2415L	2415	Missense	distal	-7	no	11.531	11.492	EPSD	COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	Q92793	CREBBP	P31749	AKT1	S2422	A2419V	2419	Missense	distal	-3	no	11.531	10.969	EPSD	COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	Q92793	CREBBP	P31749	AKT1	S2422	D2429Y	2429	Missense	distal	7	no	11.531	11.565	EPSD	COSMIC	7.780	Up-regulation
AGC_Akt_AKT1_ST	Q92793	CREBBP	P31749	AKT1	S2422	S2421F	2421	Missense	proximal	-1	no	11.531	11.497	EPSD	COSMIC;GDSC;CCLE	7.780	Down-regulation
AGC_Akt_AKT1_ST	P08670	VIM	P31749	AKT1	S7	R4K	4	Missense	distal	-3	no	12.841	8.321	EPSD	COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	P08670	VIM	P31749	AKT1	S9	R4K	4	Missense	distal	-5	no	10.359	7.962	EPSD	COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	P08670	VIM	P31749	AKT1	S26	S27R	27	Missense	proximal	1	no	11.796	11.941	EPSD	COSMIC	7.780	Up-regulation
AGC_Akt_AKT1_ST	P08670	VIM	P31749	AKT1	S39	R36H	36	Missense	distal	-3	no	11.642	6.944	PhosphoSitePlus	COSMIC	7.780	Loss
AGC_Akt_AKT1_ST	P08670	VIM	P31749	AKT1	S39	S34P	34	Missense	distal	-5	no	11.642	12.102	PhosphoSitePlus	COSMIC	7.780	Up-regulation
AGC_Akt_AKT1_ST	P08670	VIM	P31749	AKT1	T48	S55A	55	Missense	distal	7	no	9.132	9.081	EPSD	COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	P08670	VIM	P31749	AKT1	T48	S51N	51	Missense	distal	3	no	9.132	9.076	EPSD	COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	P08670	VIM	P31749	AKT1	S55	G59N	59	Missense	distal	4	no	8.851	8.787	EPSD	COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	P08670	VIM	P31749	AKT1	S55	S55A	55	Missense	central	0	yes	8.851	0.000	EPSD	COSMIC	7.780	Loss
AGC_Akt_AKT1_ST	P08670	VIM	P31749	AKT1	S55	G59V	59	Missense	distal	4	no	8.851	8.858	EPSD	COSMIC	7.780	Up-regulation
AGC_Akt_AKT1_ST	P08670	VIM	P31749	AKT1	S55	S51N	51	Missense	distal	-4	no	8.851	8.284	EPSD	COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	P08670	VIM	P31749	AKT1	S55	S56Y	56	Missense	proximal	1	no	8.851	8.844	EPSD	COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	P08670	VIM	P31749	AKT1	S72	R71Q	71	Missense	proximal	-1	no	10.158	10.126	EPSD	COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	P08670	VIM	P31749	AKT1	S72	S65F	65	Missense	distal	-7	no	10.158	9.880	EPSD	COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	P08670	VIM	P31749	AKT1	S72	V77L	77	Missense	distal	5	no	10.158	10.151	EPSD	COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	P08670	VIM	P31749	AKT1	S72	R69C	69	Missense	distal	-3	no	10.158	3.984	EPSD	COSMIC	7.780	Loss
AGC_Akt_AKT1_ST	P08670	VIM	P31749	AKT1	S278	V279M	279	Missense	proximal	1	no	8.023	7.961	EPSD	COSMIC;GDSC;CCLE	7.780	Down-regulation
AGC_Akt_AKT1_ST	P08670	VIM	P31749	AKT1	S278	N283S	283	Missense	distal	5	no	8.023	8.058	EPSD	COSMIC	7.780	Up-regulation
AGC_Akt_AKT1_ST	P08670	VIM	P31749	AKT1	S278	D271V	271	Missense	distal	-7	no	8.023	8.117	EPSD	COSMIC	7.780	Up-regulation
AGC_Akt_AKT1_ST	P08670	VIM	P31749	AKT1	S316	A312T	312	Missense	distal	-4	no	7.048	7.826	EPSD	COSMIC	7.780	Gain
AGC_Akt_AKT1_ST	P08670	VIM	P31749	AKT1	T449	T446R	446	Missense	distal	-3	no	5.049	12.070	EPSD	COSMIC	7.780	Gain
AGC_Akt_AKT1_ST	Q7L5N1	COPS6	P31749	AKT1	S60	Q61P	61	Missense	proximal	1	no	9.584	9.579	PhosphoSitePlus	COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	Q7L5N1	COPS6	P31749	AKT1	S60	M58T	58	Missense	proximal	-2	no	9.584	10.357	PhosphoSitePlus	COSMIC	7.780	Up-regulation
AGC_Akt_AKT1_ST	Q7L5N1	COPS6	P31749	AKT1	T216	S211R	211	Missense	distal	-5	no	3.794	8.265	EPSD	COSMIC	7.780	Gain
AGC_Akt_AKT1_ST	Q96F86	EDC3	P31749	AKT1	S109	S109C	109	Missense	central	0	yes	8.092	0.000	EPSD	COSMIC	7.780	Loss
AGC_Akt_AKT1_ST	Q96F86	EDC3	P31749	AKT1	S110	S109C	109	Missense	proximal	-1	no	7.836	7.776	EPSD	COSMIC	7.780	Loss
AGC_Akt_AKT1_ST	Q96F86	EDC3	P31749	AKT1	S125	K119N	119	Missense	distal	-6	no	8.609	8.542	EPSD	COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	Q96F86	EDC3	P31749	AKT1	S125	V130F	130	Missense	distal	5	no	8.609	8.596	EPSD	COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	Q96F86	EDC3	P31749	AKT1	S125	P132S	132	Missense	distal	7	no	8.609	8.667	EPSD	COSMIC;GDSC;CCLE	7.780	Up-regulation
AGC_Akt_AKT1_ST	Q96F86	EDC3	P31749	AKT1	S161	R167K	167	Missense	distal	6	no	16.373	16.384	PhosphoSitePlus	COSMIC	7.780	Up-regulation
AGC_Akt_AKT1_ST	Q96F86	EDC3	P31749	AKT1	S161	R157C	157	Missense	distal	-4	no	16.373	14.694	PhosphoSitePlus	COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	Q96F86	EDC3	P31749	AKT1	S163	R167K	167	Missense	distal	4	no	8.191	8.157	EPSD	COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	Q96F86	EDC3	P31749	AKT1	S163	R157C	157	Missense	distal	-6	no	8.191	8.010	EPSD	COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	Q96F86	EDC3	P31749	AKT1	S233	E239K	239	Missense	distal	6	no	11.116	11.185	EPSD	COSMIC	7.780	Up-regulation
AGC_Akt_AKT1_ST	Q96F86	EDC3	P31749	AKT1	T308	R303W	303	Missense	distal	-5	no	8.418	2.898	EPSD	COSMIC	7.780	Loss
AGC_Akt_AKT1_ST	Q96F86	EDC3	P31749	AKT1	T308	G309S	309	Missense	proximal	1	no	8.418	8.723	EPSD	COSMIC	7.780	Up-regulation
AGC_Akt_AKT1_ST	P14598	NCF1	P31749	AKT1	T45	R42W	42	Missense	distal	-3	no	11.183	2.242	EPSD	COSMIC	7.780	Loss
AGC_Akt_AKT1_ST	P14598	NCF1	P31749	AKT1	T93	A87T	87	Missense	distal	-6	no	12.081	12.167	EPSD	COSMIC	7.780	Up-regulation
AGC_Akt_AKT1_ST	P14598	NCF1	P31749	AKT1	T93	T100M	100	Missense	distal	7	no	12.081	12.012	EPSD	COSMIC;GDSC	7.780	Down-regulation
AGC_Akt_AKT1_ST	P14598	NCF1	P31749	AKT1	T95	T100M	100	Missense	distal	5	no	9.024	8.967	EPSD	COSMIC;GDSC	7.780	Down-regulation
AGC_Akt_AKT1_ST	P14598	NCF1	P31749	AKT1	S345	P349R	349	Missense	distal	4	no	8.508	8.363	EPSD	COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	P05455	SSB	P31749	AKT1	S94	P98R	98	Missense	distal	4	no	12.297	12.152	EPSD	COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	P05455	SSB	P31749	AKT1	S94	S94I	94	Missense	central	0	yes	12.297	0.000	EPSD	COSMIC	7.780	Loss
AGC_Akt_AKT1_ST	P05455	SSB	P31749	AKT1	T101	P98R	98	Missense	distal	-3	no	4.507	11.147	EPSD	COSMIC	7.780	Gain
AGC_Akt_AKT1_ST	P05455	SSB	P31749	AKT1	S366	E372K	372	Missense	distal	6	no	8.048	8.118	EPSD	COSMIC	7.780	Up-regulation
AGC_Akt_AKT1_ST	P05455	SSB	P31749	AKT1	S366	S366I	366	Missense	central	0	yes	8.048	0.000	EPSD	COSMIC	7.780	Loss
AGC_Akt_AKT1_ST	P05455	SSB	P31749	AKT1	T389	V382M	382	Missense	distal	-7	no	16.283	16.345	PhosphoSitePlus	COSMIC	7.780	Up-regulation
AGC_Akt_AKT1_ST	P20749	BCL3	P31749	AKT1	S367	K361E	361	Missense	distal	-6	no	12.624	12.558	EPSD	COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	P20749	BCL3	P31749	AKT1	S369	P375S	375	Missense	distal	6	no	9.057	9.150	EPSD	COSMIC	7.780	Up-regulation
AGC_Akt_AKT1_ST	P20749	BCL3	P31749	AKT1	S382	R388G	388	Missense	distal	6	no	9.514	9.410	EPSD	COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	P20749	BCL3	P31749	AKT1	S382	T381S	381	Missense	proximal	-1	no	9.514	9.508	EPSD	COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	P20749	BCL3	P31749	AKT1	S382	P375S	375	Missense	distal	-7	no	9.514	9.708	EPSD	COSMIC	7.780	Up-regulation
AGC_Akt_AKT1_ST	P20749	BCL3	P31749	AKT1	S382	R377Q	377	Missense	distal	-5	no	9.514	5.286	EPSD	COSMIC	7.780	Loss
AGC_Akt_AKT1_ST	P20749	BCL3	P31749	AKT1	S382	P383H	383	Missense	proximal	1	no	9.514	9.491	EPSD	COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	P20749	BCL3	P31749	AKT1	S386	P383H	383	Missense	distal	-3	no	6.172	8.113	EPSD	COSMIC	7.780	Gain
AGC_Akt_AKT1_ST	P20749	BCL3	P31749	AKT1	S448	P444Q	444	Missense	distal	-4	no	9.964	10.165	EPSD	COSMIC	7.780	Up-regulation
AGC_Akt_AKT1_ST	Q5UE93	PIK3R6	P31749	AKT1	T125	A120V	120	Missense	distal	-5	no	9.315	8.855	EPSD	COSMIC;CCLE	7.780	Down-regulation
AGC_Akt_AKT1_ST	Q5UE93	PIK3R6	P31749	AKT1	T125	T125K	125	Missense	central	0	yes	9.315	0.000	EPSD	COSMIC	7.780	Loss
AGC_Akt_AKT1_ST	Q5UE93	PIK3R6	P31749	AKT1	S217	H224N	224	Missense	distal	7	no	9.559	9.588	EPSD	COSMIC	7.780	Up-regulation
AGC_Akt_AKT1_ST	Q5UE93	PIK3R6	P31749	AKT1	S308	R305H	305	Missense	distal	-3	no	10.929	6.231	EPSD	COSMIC	7.780	Loss
AGC_Akt_AKT1_ST	Q5UE93	PIK3R6	P31749	AKT1	S308	R311L	311	Missense	distal	3	no	10.929	10.848	EPSD	COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	Q5UE93	PIK3R6	P31749	AKT1	S308	Q309H	309	Missense	proximal	1	no	10.929	10.902	EPSD	COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	Q5UE93	PIK3R6	P31749	AKT1	S401	T397I	397	Missense	distal	-4	no	9.797	8.359	EPSD	COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	Q5UE93	PIK3R6	P31749	AKT1	T442	E441K	441	Missense	proximal	-1	no	8.819	8.841	EPSD	COSMIC	7.780	Up-regulation
AGC_Akt_AKT1_ST	Q5UE93	PIK3R6	P31749	AKT1	T442	E441V	441	Missense	proximal	-1	no	8.819	8.799	EPSD	COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	Q5UE93	PIK3R6	P31749	AKT1	T442	E441G	441	Missense	proximal	-1	no	8.819	8.804	EPSD	COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	Q5UE93	PIK3R6	P31749	AKT1	T607	S600G	600	Missense	distal	-7	no	14.171	13.985	PhosphoSitePlus	COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	Q5UE93	PIK3R6	P31749	AKT1	S680	Q677R	677	Missense	distal	-3	no	1.009	8.220	EPSD	COSMIC	7.780	Gain
AGC_Akt_AKT1_ST	Q5UE93	PIK3R6	P31749	AKT1	T687	R684M	684	Missense	distal	-3	no	10.628	3.122	EPSD	COSMIC	7.780	Loss
AGC_Akt_AKT1_ST	Q5UE93	PIK3R6	P31749	AKT1	T687	R681Q	681	Missense	distal	-6	no	10.628	10.543	EPSD	COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	Q5UE93	PIK3R6	P31749	AKT1	S689	R684M	684	Missense	distal	-5	no	8.809	4.286	EPSD	COSMIC	7.780	Loss
AGC_Akt_AKT1_ST	Q5UE93	PIK3R6	P31749	AKT1	S689	R696H	696	Missense	distal	7	no	8.809	8.737	EPSD	COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	Q5UE93	PIK3R6	P31749	AKT1	S689	R696C	696	Missense	distal	7	no	8.809	8.679	EPSD	COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	Q96J02	ITCH	P31749	AKT1	T214	S210F	210	Missense	distal	-4	no	8.773	7.605	EPSD	COSMIC	7.780	Loss
AGC_Akt_AKT1_ST	Q96J02	ITCH	P31749	AKT1	T214	N219K	219	Missense	distal	5	no	8.773	8.808	EPSD	COSMIC	7.780	Up-regulation
AGC_Akt_AKT1_ST	Q96J02	ITCH	P31749	AKT1	T214	R215Q	215	Missense	proximal	1	no	8.773	8.478	EPSD	COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	Q96J02	ITCH	P31749	AKT1	T214	R215G	215	Missense	proximal	1	no	8.773	8.323	EPSD	COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	Q96J02	ITCH	P31749	AKT1	T218	N219K	219	Missense	proximal	1	no	10.607	10.763	EPSD	COSMIC	7.780	Up-regulation
AGC_Akt_AKT1_ST	Q96J02	ITCH	P31749	AKT1	T218	R215Q	215	Missense	distal	-3	no	10.607	3.395	EPSD	COSMIC	7.780	Loss
AGC_Akt_AKT1_ST	Q96J02	ITCH	P31749	AKT1	T218	R215G	215	Missense	distal	-3	no	10.607	3.851	EPSD	COSMIC	7.780	Loss
AGC_Akt_AKT1_ST	Q96J02	ITCH	P31749	AKT1	T218	D222N	222	Missense	distal	4	no	10.607	10.492	EPSD	COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	Q96J02	ITCH	P31749	AKT1	S236	S242P	242	Missense	distal	6	no	11.109	11.015	EPSD	COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	Q96J02	ITCH	P31749	AKT1	S236	S242F	242	Missense	distal	6	no	11.109	10.989	EPSD	COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	Q96J02	ITCH	P31749	AKT1	S257	S257Y	257	Missense	central	0	yes	8.345	0.000	PhosphoSitePlus	COSMIC	7.780	Loss
AGC_Akt_AKT1_ST	Q96J02	ITCH	P31749	AKT1	S257	P253H	253	Missense	distal	-4	no	8.345	8.109	PhosphoSitePlus	COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	Q96J02	ITCH	P31749	AKT1	S257	P262S	262	Missense	distal	5	no	8.345	8.398	PhosphoSitePlus	COSMIC	7.780	Up-regulation
AGC_Akt_AKT1_ST	Q96J02	ITCH	P31749	AKT1	T385	W386L	386	Missense	proximal	1	no	11.921	12.167	EPSD	COSMIC	7.780	Up-regulation
AGC_Akt_AKT1_ST	Q96J02	ITCH	P31749	AKT1	T385	H379R	379	Missense	distal	-6	no	11.921	12.039	EPSD	COSMIC;CCLE	7.780	Up-regulation
AGC_Akt_AKT1_ST	Q96J02	ITCH	P31749	AKT1	T385	H379D	379	Missense	distal	-6	no	11.921	11.887	EPSD	COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	Q96J02	ITCH	P31749	AKT1	S393	R395W	395	Missense	proximal	2	no	8.892	8.436	EPSD	COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	Q96J02	ITCH	P31749	AKT1	S393	W386L	386	Missense	distal	-7	no	8.892	9.025	EPSD	COSMIC	7.780	Up-regulation
AGC_Akt_AKT1_ST	Q96J02	ITCH	P31749	AKT1	T504	R501I	501	Missense	distal	-3	no	12.659	5.578	EPSD	COSMIC	7.780	Loss
AGC_Akt_AKT1_ST	Q96J02	ITCH	P31749	AKT1	T505	R501I	501	Missense	distal	-4	no	12.283	10.816	EPSD	COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	P0DMV8	HSPA1A	P31749	AKT1	T419	I414M	414	Missense	distal	-5	no	11.399	11.445	EPSD	COSMIC	7.780	Up-regulation
AGC_Akt_AKT1_ST	P0DMV8	HSPA1A	P31749	AKT1	S631	G626C	626	Missense	distal	-5	no	9.808	9.796	PhosphoSitePlus	COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	P0DMV8	HSPA1A	P31749	AKT1	S631	G629A	629	Missense	proximal	-2	no	9.808	10.051	PhosphoSitePlus	COSMIC	7.780	Up-regulation
AGC_Akt_AKT1_ST	P0DMV8	HSPA1A	P31749	AKT1	S633	G626C	626	Missense	distal	-7	no	8.994	8.757	EPSD	COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	P0DMV8	HSPA1A	P31749	AKT1	S633	G629A	629	Missense	distal	-4	no	8.994	9.001	EPSD	COSMIC	7.780	Up-regulation
AGC_Akt_AKT1_ST	P29401	TKT	P31749	AKT1	S104	D106Y	106	Missense	proximal	2	no	11.957	12.183	EPSD	COSMIC;GDSC	7.780	Up-regulation
AGC_Akt_AKT1_ST	P29401	TKT	P31749	AKT1	S104	L107F	107	Missense	distal	3	no	11.957	11.956	EPSD	COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	P29401	TKT	P31749	AKT1	S105	D106Y	106	Missense	proximal	1	no	7.744	7.950	EPSD	COSMIC;GDSC	7.780	Gain
AGC_Akt_AKT1_ST	P29401	TKT	P31749	AKT1	T249	S256Y	256	Missense	distal	7	no	11.903	11.860	EPSD	COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	P29401	TKT	P31749	AKT1	T249	G247V	247	Missense	proximal	-2	no	11.903	11.407	EPSD	COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	P29401	TKT	P31749	AKT1	T249	E252Q	252	Missense	distal	3	no	11.903	11.871	EPSD	COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	P29401	TKT	P31749	AKT1	T249	T249A	249	Missense	central	0	yes	11.903	0.000	EPSD	COSMIC	7.780	Loss
AGC_Akt_AKT1_ST	P29401	TKT	P31749	AKT1	S305	R302C	302	Missense	distal	-3	no	8.443	2.270	EPSD	COSMIC	7.780	Loss
AGC_Akt_AKT1_ST	P29401	TKT	P31749	AKT1	T382	A377V	377	Missense	distal	-5	no	11.548	11.088	PhosphoSitePlus;EPSD	COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	P29401	TKT	P31749	AKT1	T382	P384L	384	Missense	proximal	2	no	11.548	11.339	PhosphoSitePlus;EPSD	COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	P29401	TKT	P31749	AKT1	S406	A404T	404	Missense	proximal	-2	no	8.598	8.983	EPSD	COSMIC;CCLE	7.780	Up-regulation
AGC_Akt_AKT1_ST	P29401	TKT	P31749	AKT1	S406	R401C	401	Missense	distal	-5	no	8.598	4.521	EPSD	COSMIC	7.780	Loss
AGC_Akt_AKT1_ST	P29401	TKT	P31749	AKT1	S406	I410M	410	Missense	distal	4	no	8.598	8.500	EPSD	COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	P29401	TKT	P31749	AKT1	S406	R401H	401	Missense	distal	-5	no	8.598	5.503	EPSD	COSMIC	7.780	Loss
AGC_Akt_AKT1_ST	O15360	FANCA	P31749	AKT1	S309	T306R	306	Missense	distal	-3	no	3.541	10.562	EPSD	COSMIC	7.780	Gain
AGC_Akt_AKT1_ST	O15360	FANCA	P31749	AKT1	T323	T323I	323	Missense	central	0	yes	10.569	0.000	EPSD	COSMIC	7.780	Loss
AGC_Akt_AKT1_ST	O15360	FANCA	P31749	AKT1	S347	R350Q	350	Missense	distal	3	no	10.908	10.852	EPSD	COSMIC;GDSC	7.780	Down-regulation
AGC_Akt_AKT1_ST	O15360	FANCA	P31749	AKT1	S347	W346C	346	Missense	proximal	-1	no	10.908	10.898	EPSD	COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	O15360	FANCA	P31749	AKT1	S347	M342I	342	Missense	distal	-5	no	10.908	10.863	EPSD	COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	O15360	FANCA	P31749	AKT1	S391	L390I	390	Missense	proximal	-1	no	8.824	8.804	EPSD	COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	O15360	FANCA	P31749	AKT1	S581	Y578C	578	Missense	distal	-3	no	7.952	9.367	EPSD	COSMIC	7.780	Up-regulation
AGC_Akt_AKT1_ST	O15360	FANCA	P31749	AKT1	S581	L588F	588	Missense	distal	7	no	7.952	7.944	EPSD	COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	O15360	FANCA	P31749	AKT1	S581	V580M	580	Missense	proximal	-1	no	7.952	7.957	EPSD	COSMIC;GDSC;CCLE	7.780	Up-regulation
AGC_Akt_AKT1_ST	O15360	FANCA	P31749	AKT1	S581	Y579F	579	Missense	proximal	-2	no	7.952	8.007	EPSD	COSMIC	7.780	Up-regulation
AGC_Akt_AKT1_ST	O15360	FANCA	P31749	AKT1	S858	R853Q	853	Missense	distal	-5	no	8.747	4.520	EPSD	COSMIC;CCLE	7.780	Loss
AGC_Akt_AKT1_ST	O15360	FANCA	P31749	AKT1	S858	S858R	858	Missense	central	0	yes	8.747	0.000	EPSD	COSMIC;GDSC	7.780	Loss
AGC_Akt_AKT1_ST	O15360	FANCA	P31749	AKT1	S858	I865N	865	Missense	distal	7	no	8.747	8.809	EPSD	COSMIC	7.780	Up-regulation
AGC_Akt_AKT1_ST	O15360	FANCA	P31749	AKT1	S1149	S1149P	1149	Missense	central	0	yes	15.442	0.000	PhosphoSitePlus	COSMIC	7.780	Loss
AGC_Akt_AKT1_ST	O15360	FANCA	P31749	AKT1	S1149	L1143V	1143	Missense	distal	-6	no	15.442	15.417	PhosphoSitePlus	COSMIC;GDSC	7.780	Down-regulation
AGC_Akt_AKT1_ST	O15360	FANCA	P31749	AKT1	S1149	R1144Q	1144	Missense	distal	-5	no	15.442	11.214	PhosphoSitePlus	COSMIC;GDSC;CCLE	7.780	Down-regulation
AGC_Akt_AKT1_ST	O15360	FANCA	P31749	AKT1	S1149	S1149F	1149	Missense	central	0	yes	15.442	0.000	PhosphoSitePlus	COSMIC	7.780	Loss
AGC_Akt_AKT1_ST	O15360	FANCA	P31749	AKT1	S1191	S1191G	1191	Missense	central	0	yes	10.292	0.000	EPSD	COSMIC	7.780	Loss
AGC_Akt_AKT1_ST	O15360	FANCA	P31749	AKT1	S1191	R1186M	1186	Missense	distal	-5	no	10.292	5.770	EPSD	COSMIC	7.780	Loss
AGC_Akt_AKT1_ST	O15360	FANCA	P31749	AKT1	S1191	R1195W	1195	Missense	distal	4	no	10.292	10.539	EPSD	COSMIC	7.780	Up-regulation
AGC_Akt_AKT1_ST	O15360	FANCA	P31749	AKT1	S1301	I1300M	1300	Missense	proximal	-1	no	13.469	13.489	EPSD	COSMIC	7.780	Up-regulation
AGC_Akt_AKT1_ST	O15360	FANCA	P31749	AKT1	S1301	K1299N	1299	Missense	proximal	-2	no	13.469	12.532	EPSD	COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	Q9BPZ7	MAPKAP1	P31749	AKT1	S84	T86K	86	Missense	proximal	2	no	11.019	11.110	EPSD	COSMIC	7.780	Up-regulation
AGC_Akt_AKT1_ST	Q9BPZ7	MAPKAP1	P31749	AKT1	S84	E91K	91	Missense	distal	7	no	11.019	11.053	EPSD	COSMIC	7.780	Up-regulation
AGC_Akt_AKT1_ST	Q9BPZ7	MAPKAP1	P31749	AKT1	S84	R82K	82	Missense	proximal	-2	no	11.019	11.458	EPSD	COSMIC	7.780	Up-regulation
AGC_Akt_AKT1_ST	Q9BPZ7	MAPKAP1	P31749	AKT1	T86	T86K	86	Missense	central	0	yes	15.537	0.000	PhosphoSitePlus	COSMIC	7.780	Loss
AGC_Akt_AKT1_ST	Q9BPZ7	MAPKAP1	P31749	AKT1	T86	E91K	91	Missense	distal	5	no	15.537	15.571	PhosphoSitePlus	COSMIC	7.780	Up-regulation
AGC_Akt_AKT1_ST	Q9BPZ7	MAPKAP1	P31749	AKT1	T86	R82K	82	Missense	distal	-4	no	15.537	15.524	PhosphoSitePlus	COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	Q9BPZ7	MAPKAP1	P31749	AKT1	S216	Q213R	213	Missense	distal	-3	no	3.736	10.948	EPSD	COSMIC	7.780	Gain
AGC_Akt_AKT1_ST	Q9BPZ7	MAPKAP1	P31749	AKT1	S315	S315F	315	Missense	central	0	yes	13.816	0.000	EPSD	COSMIC	7.780	Loss
AGC_Akt_AKT1_ST	Q9BPZ7	MAPKAP1	P31749	AKT1	S315	A308V	308	Missense	distal	-7	no	13.816	13.688	EPSD	COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	Q9BPZ7	MAPKAP1	P31749	AKT1	S315	R311T	311	Missense	distal	-4	no	13.816	13.786	EPSD	COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	Q9BPZ7	MAPKAP1	P31749	AKT1	S512	S519F	519	Missense	distal	7	no	12.910	12.836	EPSD	COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	P53602	MVD	P31749	AKT1	S96	P103L	103	Missense	distal	7	no	16.708	16.700	PhosphoSitePlus	COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	P53602	MVD	P31749	AKT1	S96	R97W	97	Missense	proximal	1	no	16.708	16.415	PhosphoSitePlus	COSMIC;CCLE	7.780	Down-regulation
AGC_Akt_AKT1_ST	P53602	MVD	P31749	AKT1	S96	R93W	93	Missense	distal	-3	no	16.708	7.767	PhosphoSitePlus	COSMIC	7.780	Loss
AGC_Akt_AKT1_ST	P53602	MVD	P31749	AKT1	S156	R153P	153	Missense	distal	-3	no	11.774	5.134	EPSD	COSMIC	7.780	Loss
AGC_Akt_AKT1_ST	P53602	MVD	P31749	AKT1	S156	R153C	153	Missense	distal	-3	no	11.774	5.601	EPSD	COSMIC	7.780	Loss
AGC_Akt_AKT1_ST	P53602	MVD	P31749	AKT1	S156	S162I	162	Missense	distal	6	no	11.774	11.610	EPSD	COSMIC;GDSC;CCLE	7.780	Down-regulation
AGC_Akt_AKT1_ST	P53602	MVD	P31749	AKT1	S158	R153P	153	Missense	distal	-5	no	8.711	4.700	EPSD	COSMIC	7.780	Loss
AGC_Akt_AKT1_ST	P53602	MVD	P31749	AKT1	S158	R153C	153	Missense	distal	-5	no	8.711	4.634	EPSD	COSMIC	7.780	Loss
AGC_Akt_AKT1_ST	P53602	MVD	P31749	AKT1	S158	S162I	162	Missense	distal	4	no	8.711	8.972	EPSD	COSMIC;GDSC;CCLE	7.780	Up-regulation
AGC_Akt_AKT1_ST	Q9BWT1	CDCA7	P31749	AKT1	S95	Q93L	93	Missense	proximal	-2	no	12.517	12.361	EPSD	COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	Q9BWT1	CDCA7	P31749	AKT1	T163	V167I	167	Missense	distal	4	no	14.466	14.548	PhosphoSitePlus	COSMIC	7.780	Up-regulation
AGC_Akt_AKT1_ST	Q9BWT1	CDCA7	P31749	AKT1	T163	R162C	162	Missense	proximal	-1	no	14.466	14.396	PhosphoSitePlus	COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	Q9BWT1	CDCA7	P31749	AKT1	T163	G166D	166	Missense	distal	3	no	14.466	14.446	PhosphoSitePlus	COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	Q9BWT1	CDCA7	P31749	AKT1	S231	R225T	225	Missense	distal	-6	no	11.194	11.191	EPSD	COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	Q13185	CBX3	P31749	AKT1	S93	K90N	90	Missense	distal	-3	no	8.448	5.492	EPSD	COSMIC	7.780	Loss
AGC_Akt_AKT1_ST	Q13185	CBX3	P31749	AKT1	S95	K90N	90	Missense	distal	-5	no	10.725	8.637	EPSD	COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	Q13185	CBX3	P31749	AKT1	S97	K90N	90	Missense	distal	-7	no	9.435	9.278	EPSD	COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	Q15942	ZYX	P31749	AKT1	S11	P6S	6	Missense	distal	-5	no	8.020	7.560	EPSD	COSMIC	7.780	Loss
AGC_Akt_AKT1_ST	Q15942	ZYX	P31749	AKT1	S11	S13F	13	Missense	proximal	2	no	8.020	7.442	EPSD	COSMIC	7.780	Loss
AGC_Akt_AKT1_ST	Q15942	ZYX	P31749	AKT1	S142	E139K	139	Missense	distal	-3	no	6.920	8.971	PhosphoSitePlus	COSMIC	7.780	Gain
AGC_Akt_AKT1_ST	Q15942	ZYX	P31749	AKT1	S143	E139K	139	Missense	distal	-4	no	10.254	10.838	EPSD	COSMIC	7.780	Up-regulation
AGC_Akt_AKT1_ST	Q15942	ZYX	P31749	AKT1	S170	R167Q	167	Missense	distal	-3	no	11.209	3.998	EPSD	COSMIC	7.780	Loss
AGC_Akt_AKT1_ST	Q15942	ZYX	P31749	AKT1	S170	P174L	174	Missense	distal	4	no	11.209	11.242	EPSD	COSMIC	7.780	Up-regulation
AGC_Akt_AKT1_ST	Q15942	ZYX	P31749	AKT1	S170	S170F	170	Missense	central	0	yes	11.209	0.000	EPSD	COSMIC	7.780	Loss
AGC_Akt_AKT1_ST	Q15942	ZYX	P31749	AKT1	S206	P203H	203	Missense	distal	-3	no	6.784	8.725	EPSD	COSMIC;GDSC;CCLE	7.780	Gain
AGC_Akt_AKT1_ST	Q15942	ZYX	P31749	AKT1	S258	S259F	259	Missense	proximal	1	no	8.170	8.188	EPSD	COSMIC	7.780	Up-regulation
AGC_Akt_AKT1_ST	Q15942	ZYX	P31749	AKT1	S258	A261T	261	Missense	distal	3	no	8.170	8.227	EPSD	COSMIC	7.780	Up-regulation
AGC_Akt_AKT1_ST	Q9UNN5	FAF1	P31749	AKT1	S270	E276G	276	Missense	distal	6	no	13.035	12.989	EPSD	COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	Q9UNN5	FAF1	P31749	AKT1	S270	R268I	268	Missense	proximal	-2	no	13.035	11.983	EPSD	COSMIC;GDSC;CCLE	7.780	Down-regulation
AGC_Akt_AKT1_ST	Q09472	EP300	P31749	AKT1	S12	E7K	7	Missense	distal	-5	no	6.570	8.268	EPSD	COSMIC	7.780	Gain
AGC_Akt_AKT1_ST	Q09472	EP300	P31749	AKT1	S12	G9R	9	Missense	distal	-3	no	6.570	13.326	EPSD	COSMIC	7.780	Gain
AGC_Akt_AKT1_ST	Q09472	EP300	P31749	AKT1	S19	A13T	13	Missense	distal	-6	no	8.729	8.815	EPSD	COSMIC	7.780	Up-regulation
AGC_Akt_AKT1_ST	Q09472	EP300	P31749	AKT1	S19	P21L	21	Missense	proximal	2	no	8.729	8.520	EPSD	COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	Q09472	EP300	P31749	AKT1	S19	A13V	13	Missense	distal	-6	no	8.729	8.709	EPSD	COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	Q09472	EP300	P31749	AKT1	S19	S12A	12	Missense	distal	-7	no	8.729	8.580	EPSD	COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	Q09472	EP300	P31749	AKT1	S20	A13T	13	Missense	distal	-7	no	11.821	12.021	EPSD	COSMIC	7.780	Up-regulation
AGC_Akt_AKT1_ST	Q09472	EP300	P31749	AKT1	S20	P21L	21	Missense	proximal	1	no	11.821	12.075	EPSD	COSMIC	7.780	Up-regulation
AGC_Akt_AKT1_ST	Q09472	EP300	P31749	AKT1	S20	A13V	13	Missense	distal	-7	no	11.821	11.693	EPSD	COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	Q09472	EP300	P31749	AKT1	S89	M95V	95	Missense	distal	6	no	11.079	11.064	EPSD	COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	Q09472	EP300	P31749	AKT1	S89	S87Y	87	Missense	proximal	-2	no	11.079	10.157	EPSD	COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	Q09472	EP300	P31749	AKT1	S831	L827P	827	Missense	distal	-4	no	8.571	8.959	EPSD	COSMIC	7.780	Up-regulation
AGC_Akt_AKT1_ST	Q09472	EP300	P31749	AKT1	S831	R838S	838	Missense	distal	7	no	8.571	8.564	EPSD	COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	Q09472	EP300	P31749	AKT1	T841	T845S	845	Missense	distal	4	no	10.699	10.704	EPSD	COSMIC	7.780	Up-regulation
AGC_Akt_AKT1_ST	Q09472	EP300	P31749	AKT1	T841	P842S	842	Missense	proximal	1	no	10.699	10.854	EPSD	COSMIC;CCLE	7.780	Up-regulation
AGC_Akt_AKT1_ST	Q09472	EP300	P31749	AKT1	T841	T839I	839	Missense	proximal	-2	no	10.699	9.524	EPSD	COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	Q09472	EP300	P31749	AKT1	T841	P846S	846	Missense	distal	5	no	10.699	10.752	EPSD	COSMIC	7.780	Up-regulation
AGC_Akt_AKT1_ST	Q09472	EP300	P31749	AKT1	T841	P847S	847	Missense	distal	6	no	10.699	10.793	EPSD	COSMIC	7.780	Up-regulation
AGC_Akt_AKT1_ST	Q09472	EP300	P31749	AKT1	T841	P842L	842	Missense	proximal	1	no	10.699	10.953	EPSD	COSMIC	7.780	Up-regulation
AGC_Akt_AKT1_ST	Q09472	EP300	P31749	AKT1	T841	R838S	838	Missense	distal	-3	no	10.699	2.923	EPSD	COSMIC	7.780	Loss
AGC_Akt_AKT1_ST	Q09472	EP300	P31749	AKT1	T885	P882R	882	Missense	distal	-3	no	4.846	11.486	EPSD	COSMIC	7.780	Gain
AGC_Akt_AKT1_ST	Q09472	EP300	P31749	AKT1	T887	P882R	882	Missense	distal	-5	no	4.307	8.318	EPSD	COSMIC	7.780	Gain
AGC_Akt_AKT1_ST	Q09472	EP300	P31749	AKT1	S1072	R1067C	1067	Missense	distal	-5	no	9.721	5.644	EPSD	COSMIC;CCLE	7.780	Loss
AGC_Akt_AKT1_ST	Q09472	EP300	P31749	AKT1	S1072	Y1066N	1066	Missense	distal	-6	no	9.721	9.733	EPSD	COSMIC	7.780	Up-regulation
AGC_Akt_AKT1_ST	Q09472	EP300	P31749	AKT1	S1072	R1076H	1076	Missense	distal	4	no	9.721	9.906	EPSD	COSMIC	7.780	Up-regulation
AGC_Akt_AKT1_ST	Q09472	EP300	P31749	AKT1	S1072	D1069N	1069	Missense	distal	-3	no	9.721	8.195	EPSD	COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	Q09472	EP300	P31749	AKT1	S1072	P1078H	1078	Missense	distal	6	no	9.721	9.694	EPSD	COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	Q09472	EP300	P31749	AKT1	S1072	P1078L	1078	Missense	distal	6	no	9.721	9.711	EPSD	COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	Q09472	EP300	P31749	AKT1	S1072	S1072F	1072	Missense	central	0	yes	9.721	0.000	EPSD	COSMIC	7.780	Loss
AGC_Akt_AKT1_ST	Q09472	EP300	P31749	AKT1	S1072	R1076S	1076	Missense	distal	4	no	9.721	9.710	EPSD	COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	Q09472	EP300	P31749	AKT1	T1190	D1188N	1188	Missense	proximal	-2	no	8.801	9.508	EPSD	COSMIC	7.780	Up-regulation
AGC_Akt_AKT1_ST	Q09472	EP300	P31749	AKT1	T1190	R1197W	1197	Missense	distal	7	no	8.801	8.702	EPSD	COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	Q09472	EP300	P31749	AKT1	T1190	Q1195H	1195	Missense	distal	5	no	8.801	8.777	EPSD	COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	Q09472	EP300	P31749	AKT1	T1190	C1183Y	1183	Missense	distal	-7	no	8.801	9.017	EPSD	COSMIC	7.780	Up-regulation
AGC_Akt_AKT1_ST	Q09472	EP300	P31749	AKT1	S1295	T1300I	1300	Missense	distal	5	no	11.851	11.754	EPSD	COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	Q09472	EP300	P31749	AKT1	S1295	L1298R	1298	Missense	distal	3	no	11.851	11.932	EPSD	COSMIC	7.780	Up-regulation
AGC_Akt_AKT1_ST	Q09472	EP300	P31749	AKT1	S1577	G1572R	1572	Missense	distal	-5	no	4.596	8.661	EPSD	COSMIC	7.780	Gain
AGC_Akt_AKT1_ST	Q09472	EP300	P31749	AKT1	T1632	L1639P	1639	Missense	distal	7	no	7.981	7.989	EPSD	COSMIC	7.780	Up-regulation
AGC_Akt_AKT1_ST	Q09472	EP300	P31749	AKT1	T1632	D1625V	1625	Missense	distal	-7	no	7.981	8.075	EPSD	COSMIC	7.780	Up-regulation
AGC_Akt_AKT1_ST	Q09472	EP300	P31749	AKT1	T1632	D1628N	1628	Missense	distal	-4	no	7.981	8.701	EPSD	COSMIC	7.780	Up-regulation
AGC_Akt_AKT1_ST	Q09472	EP300	P31749	AKT1	T1632	R1627Q	1627	Missense	distal	-5	no	7.981	3.753	EPSD	COSMIC	7.780	Loss
AGC_Akt_AKT1_ST	Q09472	EP300	P31749	AKT1	T1632	G1626V	1626	Missense	distal	-6	no	7.981	7.985	EPSD	COSMIC	7.780	Up-regulation
AGC_Akt_AKT1_ST	Q09472	EP300	P31749	AKT1	T1632	H1638Y	1638	Missense	distal	6	no	7.981	8.013	EPSD	COSMIC	7.780	Up-regulation
AGC_Akt_AKT1_ST	Q09472	EP300	P31749	AKT1	T1632	D1625G	1625	Missense	distal	-7	no	7.981	8.166	EPSD	COSMIC	7.780	Up-regulation
AGC_Akt_AKT1_ST	Q09472	EP300	P31749	AKT1	S1734	S1730Y	1730	Missense	distal	-4	no	12.320	11.461	EPSD	COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	Q09472	EP300	P31749	AKT1	S1734	S1730F	1730	Missense	distal	-4	no	12.320	11.153	EPSD	COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	Q09472	EP300	P31749	AKT1	S1734	R1732H	1732	Missense	proximal	-2	no	12.320	11.460	EPSD	COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	Q09472	EP300	P31749	AKT1	S1754	R1749L	1749	Missense	distal	-5	no	10.638	6.512	EPSD	COSMIC	7.780	Loss
AGC_Akt_AKT1_ST	Q09472	EP300	P31749	AKT1	S1754	L1755V	1755	Missense	proximal	1	no	10.638	10.539	EPSD	COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	Q09472	EP300	P31749	AKT1	S1834	G1839D	1839	Missense	distal	5	no	16.157	16.145	PhosphoSitePlus	COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	Q09472	EP300	P31749	AKT1	S1834	T1838N	1838	Missense	distal	4	no	16.157	16.271	PhosphoSitePlus	COSMIC	7.780	Up-regulation
AGC_Akt_AKT1_ST	Q09472	EP300	P31749	AKT1	S1834	G1839S	1839	Missense	distal	5	no	16.157	16.220	PhosphoSitePlus	COSMIC	7.780	Up-regulation
AGC_Akt_AKT1_ST	Q09472	EP300	P31749	AKT1	S1834	R1837W	1837	Missense	distal	3	no	16.157	16.045	PhosphoSitePlus	COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	Q09472	EP300	P31749	AKT1	S2320	H2324T	2324	Missense	distal	4	no	10.616	10.416	EPSD	COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	Q09472	EP300	P31749	AKT1	S2320	P2314T	2314	Missense	distal	-6	no	10.616	10.711	EPSD	COSMIC	7.780	Up-regulation
AGC_Akt_AKT1_ST	Q09472	EP300	P31749	AKT1	S2320	R2317W	2317	Missense	distal	-3	no	10.616	1.676	EPSD	COSMIC	7.780	Loss
AGC_Akt_AKT1_ST	Q09472	EP300	P31749	AKT1	S2320	H2324Y	2324	Missense	distal	4	no	10.616	10.557	EPSD	COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	Q99623	PHB2	P31749	AKT1	T169	R166W	166	Missense	distal	-3	no	10.513	1.573	EPSD	COSMIC;CCLE	7.780	Loss
AGC_Akt_AKT1_ST	Q99623	PHB2	P31749	AKT1	T169	R165C	165	Missense	distal	-4	no	10.513	8.835	EPSD	COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	Q99623	PHB2	P31749	AKT1	S176	D180Y	180	Missense	distal	4	no	8.363	8.274	EPSD;PhosphoSitePlus	COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	Q99623	PHB2	P31749	AKT1	T194	A196V	196	Missense	proximal	2	no	10.881	10.719	EPSD	COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	Q99623	PHB2	P31749	AKT1	S293	K296N	296	Missense	distal	3	no	8.338	8.279	EPSD	COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	Q99623	PHB2	P31749	AKT1	S293	R289S	289	Missense	distal	-4	no	8.338	8.252	EPSD	COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	Q99623	PHB2	P31749	AKT1	S293	K298Q	298	Missense	distal	5	no	8.338	8.293	EPSD	COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	Q99623	PHB2	P31749	AKT1	S293	K298T	298	Missense	distal	5	no	8.338	8.337	EPSD	COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	Q9UBP6	METTL1	P31749	AKT1	S177	R174L	174	Missense	distal	-3	no	12.435	5.442	EPSD	COSMIC	7.780	Loss
AGC_Akt_AKT1_ST	Q9UBP6	METTL1	P31749	AKT1	S177	R174Q	174	Missense	distal	-3	no	12.435	5.224	EPSD	COSMIC	7.780	Loss
AGC_Akt_AKT1_ST	P17302	GJA1	P31749	AKT1	S244	K243N	243	Missense	proximal	-1	no	11.197	11.172	EPSD	COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	P17302	GJA1	P31749	AKT1	S244	D245Y	245	Missense	proximal	1	no	11.197	11.403	EPSD	COSMIC	7.780	Up-regulation
AGC_Akt_AKT1_ST	P17302	GJA1	P31749	AKT1	S296	R299L	299	Missense	distal	3	no	9.909	9.828	EPSD	COSMIC;GDSC;CCLE	7.780	Down-regulation
AGC_Akt_AKT1_ST	P17302	GJA1	P31749	AKT1	S296	N302S	302	Missense	distal	6	no	9.909	9.977	EPSD	COSMIC	7.780	Up-regulation
AGC_Akt_AKT1_ST	P17302	GJA1	P31749	AKT1	S306	N302S	302	Missense	distal	-4	no	7.263	7.830	EPSD	COSMIC	7.780	Gain
AGC_Akt_AKT1_ST	P17302	GJA1	P31749	AKT1	S365	P363L	363	Missense	proximal	-2	no	13.378	13.345	EPSD	COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	P17302	GJA1	P31749	AKT1	S365	R370S	370	Missense	distal	5	no	13.378	13.370	EPSD	COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	P17302	GJA1	P31749	AKT1	S368	P363L	363	Missense	distal	-5	no	7.958	7.842	EPSD	COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	P17302	GJA1	P31749	AKT1	S368	R370S	370	Missense	proximal	2	no	7.958	8.130	EPSD	COSMIC	7.780	Up-regulation
AGC_Akt_AKT1_ST	P17302	GJA1	P31749	AKT1	S369	P363L	363	Missense	distal	-6	no	14.385	14.398	EPSD	COSMIC	7.780	Up-regulation
AGC_Akt_AKT1_ST	P17302	GJA1	P31749	AKT1	S369	R370S	370	Missense	proximal	1	no	14.385	14.240	EPSD	COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	P17302	GJA1	P31749	AKT1	S372	R370S	370	Missense	proximal	-2	no	8.283	8.472	EPSD	COSMIC	7.780	Up-regulation
AGC_Akt_AKT1_ST	P17302	GJA1	P31749	AKT1	S373	R370S	370	Missense	distal	-3	no	14.796	7.019	PhosphoSitePlus	COSMIC	7.780	Loss
AGC_Akt_AKT1_ST	Q9H4X1	RGCC	P31749	AKT1	S64	A66G	66	Missense	proximal	2	no	11.300	11.343	EPSD	COSMIC	7.780	Up-regulation
AGC_Akt_AKT1_ST	Q9H4X1	RGCC	P31749	AKT1	S65	A66G	66	Missense	proximal	1	no	12.435	12.204	EPSD	COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	Q9H4X1	RGCC	P31749	AKT1	S67	A66G	66	Missense	proximal	-1	no	9.315	9.306	EPSD	COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	P06748	NPM1	P31749	AKT1	S48	K54N	54	Missense	distal	6	no	11.025	10.947	PhosphoSitePlus	COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	P06748	NPM1	P31749	AKT1	S106	G113V	113	Missense	distal	7	no	9.646	9.665	EPSD	COSMIC	7.780	Up-regulation
AGC_Akt_AKT1_ST	P06748	NPM1	P31749	AKT1	S106	I111N	111	Missense	distal	5	no	9.646	9.709	EPSD	COSMIC	7.780	Up-regulation
AGC_Akt_AKT1_ST	P06748	NPM1	P31749	AKT1	S227	G224R	224	Missense	distal	-3	no	4.879	11.635	EPSD	COSMIC	7.780	Gain
AGC_Akt_AKT1_ST	Q92945	KHSRP	P31749	AKT1	S193	S193C	193	Missense	central	0	yes	13.425	0.000	PhosphoSitePlus	COSMIC;CCLE	7.780	Loss
AGC_Akt_AKT1_ST	Q92945	KHSRP	P31749	AKT1	T195	S193C	193	Missense	proximal	-2	no	10.007	8.354	EPSD	COSMIC;CCLE	7.780	Down-regulation
AGC_Akt_AKT1_ST	Q92945	KHSRP	P31749	AKT1	S319	G312R	312	Missense	distal	-7	no	7.921	8.163	EPSD	COSMIC	7.780	Up-regulation
AGC_Akt_AKT1_ST	O60331	PIP5K1C	P31749	AKT1	S66	E68K	68	Missense	proximal	2	no	7.730	7.935	EPSD	COSMIC	7.780	Gain
AGC_Akt_AKT1_ST	O60331	PIP5K1C	P31749	AKT1	T135	R142S	142	Missense	distal	7	no	9.425	9.418	EPSD	COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	O60331	PIP5K1C	P31749	AKT1	T135	R142C	142	Missense	distal	7	no	9.425	9.295	EPSD	COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	O60331	PIP5K1C	P31749	AKT1	T135	R142H	142	Missense	distal	7	no	9.425	9.353	EPSD	COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	O60331	PIP5K1C	P31749	AKT1	S448	T442M	442	Missense	distal	-6	no	12.315	12.222	EPSD	COSMIC;CCLE	7.780	Down-regulation
AGC_Akt_AKT1_ST	O60331	PIP5K1C	P31749	AKT1	S448	S448F	448	Missense	central	0	yes	12.315	0.000	EPSD	COSMIC	7.780	Loss
AGC_Akt_AKT1_ST	O60331	PIP5K1C	P31749	AKT1	S449	T442M	442	Missense	distal	-7	no	9.630	9.364	EPSD	COSMIC;CCLE	7.780	Down-regulation
AGC_Akt_AKT1_ST	O60331	PIP5K1C	P31749	AKT1	S449	S448F	448	Missense	proximal	-1	no	9.630	9.595	EPSD	COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	O60331	PIP5K1C	P31749	AKT1	S541	R538L	538	Missense	distal	-3	no	11.411	4.417	EPSD	COSMIC	7.780	Loss
AGC_Akt_AKT1_ST	O60331	PIP5K1C	P31749	AKT1	T543	R538L	538	Missense	distal	-5	no	10.500	6.374	EPSD	COSMIC	7.780	Loss
AGC_Akt_AKT1_ST	O60331	PIP5K1C	P31749	AKT1	T553	R552G	552	Missense	proximal	-1	no	14.941	14.902	EPSD	COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	O60331	PIP5K1C	P31749	AKT1	T553	R552C	552	Missense	proximal	-1	no	14.941	14.871	EPSD	COSMIC;GDSC;CCLE	7.780	Down-regulation
AGC_Akt_AKT1_ST	O60331	PIP5K1C	P31749	AKT1	T553	R552L	552	Missense	proximal	-1	no	14.941	14.903	EPSD	COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	O60331	PIP5K1C	P31749	AKT1	S555	R552G	552	Missense	distal	-3	no	16.291	9.535	PhosphoSitePlus	COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	O60331	PIP5K1C	P31749	AKT1	S555	R552C	552	Missense	distal	-3	no	16.291	10.118	PhosphoSitePlus	COSMIC;GDSC;CCLE	7.780	Down-regulation
AGC_Akt_AKT1_ST	O60331	PIP5K1C	P31749	AKT1	S555	R552L	552	Missense	distal	-3	no	16.291	9.297	PhosphoSitePlus	COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	O60331	PIP5K1C	P31749	AKT1	S556	R552G	552	Missense	distal	-4	no	8.805	7.990	EPSD	COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	O60331	PIP5K1C	P31749	AKT1	S556	R552C	552	Missense	distal	-4	no	8.805	7.126	EPSD	COSMIC;GDSC;CCLE	7.780	Loss
AGC_Akt_AKT1_ST	O60331	PIP5K1C	P31749	AKT1	S556	R552L	552	Missense	distal	-4	no	8.805	7.595	EPSD	COSMIC	7.780	Loss
AGC_Akt_AKT1_ST	O60331	PIP5K1C	P31749	AKT1	S650	L652F	652	Missense	proximal	2	no	7.851	7.819	EPSD	COSMIC;CCLE	7.780	Down-regulation
AGC_Akt_AKT1_ST	O60331	PIP5K1C	P31749	AKT1	S650	H653P	653	Missense	distal	3	no	7.851	7.870	EPSD	COSMIC	7.780	Up-regulation
AGC_Akt_AKT1_ST	Q12906	ILF3	P31749	AKT1	S545	E542K	542	Missense	distal	-3	no	6.297	8.348	EPSD	COSMIC;CCLE	7.780	Gain
AGC_Akt_AKT1_ST	Q12906	ILF3	P31749	AKT1	S647	R644Q	644	Missense	distal	-3	no	16.183	8.972	PhosphoSitePlus	COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	Q12906	ILF3	P31749	AKT1	S647	R653W	653	Missense	distal	6	no	16.183	16.025	PhosphoSitePlus	COSMIC;GDSC	7.780	Down-regulation
AGC_Akt_AKT1_ST	Q12906	ILF3	P31749	AKT1	S647	R642Q	642	Missense	distal	-5	no	16.183	11.955	PhosphoSitePlus	COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	Q12906	ILF3	P31749	AKT1	S647	R649W	649	Missense	proximal	2	no	16.183	15.728	PhosphoSitePlus	COSMIC;CCLE	7.780	Down-regulation
AGC_Akt_AKT1_ST	Q12906	ILF3	P31749	AKT1	S696	S691R	691	Missense	distal	-5	no	3.636	8.106	EPSD	COSMIC	7.780	Gain
AGC_Akt_AKT1_ST	Q12906	ILF3	P31749	AKT1	S710	G705R	705	Missense	distal	-5	no	3.983	8.047	EPSD	COSMIC	7.780	Gain
AGC_Akt_AKT1_ST	Q12906	ILF3	P31749	AKT1	S820	G817S	817	Missense	distal	-3	no	8.780	7.759	EPSD	COSMIC;CCLE	7.780	Loss
AGC_Akt_AKT1_ST	Q12906	ILF3	P31749	AKT1	S854	G851R	851	Missense	distal	-3	no	6.963	13.719	EPSD	COSMIC	7.780	Gain
AGC_Akt_AKT1_ST	Q8IYJ3	SYTL1	P31749	AKT1	S111	A117D	117	Missense	distal	6	no	13.062	12.995	EPSD	COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	Q8IYJ3	SYTL1	P31749	AKT1	T112	A117D	117	Missense	distal	5	no	11.863	11.839	EPSD	COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	Q8IYJ3	SYTL1	P31749	AKT1	S237	S239I	239	Missense	proximal	2	no	10.420	9.764	EPSD	COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	Q8IYJ3	SYTL1	P31749	AKT1	S237	R234S	234	Missense	distal	-3	no	10.420	2.644	EPSD	COSMIC	7.780	Loss
AGC_Akt_AKT1_ST	Q8IYJ3	SYTL1	P31749	AKT1	S239	S239I	239	Missense	central	0	yes	10.114	0.000	EPSD	COSMIC	7.780	Loss
AGC_Akt_AKT1_ST	Q8IYJ3	SYTL1	P31749	AKT1	S239	R234S	234	Missense	distal	-5	no	10.114	5.643	EPSD	COSMIC	7.780	Loss
AGC_Akt_AKT1_ST	Q8IYJ3	SYTL1	P31749	AKT1	S301	V305I	305	Missense	distal	4	no	11.324	11.405	EPSD	COSMIC	7.780	Up-regulation
AGC_Akt_AKT1_ST	Q8IYJ3	SYTL1	P31749	AKT1	S301	R298H	298	Missense	distal	-3	no	11.324	6.625	EPSD	COSMIC	7.780	Loss
AGC_Akt_AKT1_ST	Q8IYJ3	SYTL1	P31749	AKT1	S468	R461H	461	Missense	distal	-7	no	9.752	9.450	EPSD	COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	Q8IYJ3	SYTL1	P31749	AKT1	S468	R466Q	466	Missense	proximal	-2	no	9.752	9.239	EPSD	COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	Q8IYJ3	SYTL1	P31749	AKT1	S470	R466Q	466	Missense	distal	-4	no	12.416	11.795	EPSD	COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	Q8WYL5	SSH1	P31749	AKT1	T11	A14T	14	Missense	distal	3	no	12.776	12.833	EPSD	COSMIC	7.780	Up-regulation
AGC_Akt_AKT1_ST	Q8WYL5	SSH1	P31749	AKT1	S13	A14T	14	Missense	proximal	1	no	11.720	11.987	EPSD	COSMIC	7.780	Up-regulation
AGC_Akt_AKT1_ST	Q8WYL5	SSH1	P31749	AKT1	S37	E40K	40	Missense	distal	3	no	9.289	9.332	EPSD	COSMIC	7.780	Up-regulation
AGC_Akt_AKT1_ST	Q8WYL5	SSH1	P31749	AKT1	S37	S39N	39	Missense	proximal	2	no	9.289	9.020	EPSD	COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	Q8WYL5	SSH1	P31749	AKT1	S237	P235S	235	Missense	proximal	-2	no	10.340	11.164	EPSD	COSMIC	7.780	Up-regulation
AGC_Akt_AKT1_ST	Q8WYL5	SSH1	P31749	AKT1	S402	V397M	397	Missense	distal	-5	no	11.598	11.390	EPSD	COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	Q8WYL5	SSH1	P31749	AKT1	S402	G396C	396	Missense	distal	-6	no	11.598	11.531	EPSD	COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	Q8WYL5	SSH1	P31749	AKT1	T430	M437I	437	Missense	distal	7	no	12.426	12.388	EPSD	COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	Q8WYL5	SSH1	P31749	AKT1	T430	R427H	427	Missense	distal	-3	no	12.426	7.727	EPSD	COSMIC	7.780	Loss
AGC_Akt_AKT1_ST	Q8WYL5	SSH1	P31749	AKT1	T430	A434V	434	Missense	distal	4	no	12.426	12.482	EPSD	COSMIC	7.780	Up-regulation
AGC_Akt_AKT1_ST	Q8WYL5	SSH1	P31749	AKT1	T430	A434S	434	Missense	distal	4	no	12.426	12.302	EPSD	COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	Q8WYL5	SSH1	P31749	AKT1	S441	M437I	437	Missense	distal	-4	no	11.875	11.402	EPSD	COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	Q8WYL5	SSH1	P31749	AKT1	S441	A434V	434	Missense	distal	-7	no	11.875	11.746	EPSD	COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	Q8WYL5	SSH1	P31749	AKT1	S441	A434S	434	Missense	distal	-7	no	11.875	12.024	EPSD	COSMIC	7.780	Up-regulation
AGC_Akt_AKT1_ST	Q8WYL5	SSH1	P31749	AKT1	S441	R438L	438	Missense	distal	-3	no	11.875	4.881	EPSD	COSMIC	7.780	Loss
AGC_Akt_AKT1_ST	Q8WYL5	SSH1	P31749	AKT1	S441	R438H	438	Missense	distal	-3	no	11.875	7.176	EPSD	COSMIC	7.780	Loss
AGC_Akt_AKT1_ST	Q8WYL5	SSH1	P31749	AKT1	S441	R438C	438	Missense	distal	-3	no	11.875	5.701	EPSD	COSMIC	7.780	Loss
AGC_Akt_AKT1_ST	Q8WYL5	SSH1	P31749	AKT1	T462	R459H	459	Missense	distal	-3	no	8.742	4.043	EPSD	COSMIC;GDSC	7.780	Loss
AGC_Akt_AKT1_ST	Q8WYL5	SSH1	P31749	AKT1	S464	R459H	459	Missense	distal	-5	no	9.723	6.629	EPSD	COSMIC;GDSC	7.780	Loss
AGC_Akt_AKT1_ST	Q8WYL5	SSH1	P31749	AKT1	S515	P517S	517	Missense	proximal	2	no	11.612	11.949	EPSD	COSMIC	7.780	Up-regulation
AGC_Akt_AKT1_ST	Q8WYL5	SSH1	P31749	AKT1	S515	R512W	512	Missense	distal	-3	no	11.612	2.672	EPSD	COSMIC	7.780	Loss
AGC_Akt_AKT1_ST	Q8WYL5	SSH1	P31749	AKT1	S583	R580Q	580	Missense	distal	-3	no	14.261	7.050	EPSD	COSMIC	7.780	Loss
AGC_Akt_AKT1_ST	Q8WYL5	SSH1	P31749	AKT1	S583	R580W	580	Missense	distal	-3	no	14.261	5.321	EPSD	COSMIC	7.780	Loss
AGC_Akt_AKT1_ST	Q8WYL5	SSH1	P31749	AKT1	S583	S576G	576	Missense	distal	-7	no	14.261	14.075	EPSD	COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	Q8WYL5	SSH1	P31749	AKT1	S696	R697M	697	Missense	proximal	1	no	8.131	7.923	EPSD	COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	Q8WYL5	SSH1	P31749	AKT1	S696	P690S	690	Missense	distal	-6	no	8.131	8.195	EPSD	COSMIC	7.780	Up-regulation
AGC_Akt_AKT1_ST	Q8WYL5	SSH1	P31749	AKT1	S834	V835L	835	Missense	proximal	1	no	12.667	12.767	EPSD	COSMIC	7.780	Up-regulation
AGC_Akt_AKT1_ST	Q8WYL5	SSH1	P31749	AKT1	S834	V835M	835	Missense	proximal	1	no	12.667	12.606	EPSD	COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	Q8WYL5	SSH1	P31749	AKT1	S834	A840V	840	Missense	distal	6	no	12.667	12.636	EPSD	COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	Q8WYL5	SSH1	P31749	AKT1	S883	G878R	878	Missense	distal	-5	no	6.610	10.674	EPSD	COSMIC	7.780	Gain
AGC_Akt_AKT1_ST	Q8WYL5	SSH1	P31749	AKT1	T968	R975H	975	Missense	distal	7	no	9.242	9.170	EPSD	COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	Q8WYL5	SSH1	P31749	AKT1	T968	R961Q	961	Missense	distal	-7	no	9.242	9.048	EPSD	COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	Q8WYL5	SSH1	P31749	AKT1	T968	S971F	971	Missense	distal	3	no	9.242	9.144	EPSD	COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	Q8WYL5	SSH1	P31749	AKT1	T968	A965T	965	Missense	distal	-3	no	9.242	8.523	EPSD	COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	Q8WYL5	SSH1	P31749	AKT1	T968	A965V	965	Missense	distal	-3	no	9.242	8.680	EPSD	COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	Q8WYL5	SSH1	P31749	AKT1	T968	R975C	975	Missense	distal	7	no	9.242	9.112	EPSD	COSMIC;GDSC;CCLE	7.780	Down-regulation
AGC_Akt_AKT1_ST	Q8WYL5	SSH1	P31749	AKT1	T968	R963W	963	Missense	distal	-5	no	9.242	3.722	EPSD	COSMIC	7.780	Loss
AGC_Akt_AKT1_ST	Q8WYL5	SSH1	P31749	AKT1	S978	R975H	975	Missense	distal	-3	no	12.062	7.363	EPSD	COSMIC	7.780	Loss
AGC_Akt_AKT1_ST	Q8WYL5	SSH1	P31749	AKT1	S978	S971F	971	Missense	distal	-7	no	12.062	11.784	EPSD	COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	Q8WYL5	SSH1	P31749	AKT1	S978	R975C	975	Missense	distal	-3	no	12.062	5.888	EPSD	COSMIC;GDSC;CCLE	7.780	Loss
AGC_Akt_AKT1_ST	O15111	CHUK	P31749	AKT1	T23	E16V	16	Missense	distal	-7	no	13.896	13.768	PhosphoSitePlus	COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	O15111	CHUK	P31749	AKT1	T23	M17T	17	Missense	distal	-6	no	13.896	13.988	PhosphoSitePlus	COSMIC	7.780	Up-regulation
AGC_Akt_AKT1_ST	P35222	CTNNB1	P31749	AKT1	S23	Q28E	28	Missense	distal	5	no	11.090	11.101	EPSD	COSMIC	7.780	Up-regulation
AGC_Akt_AKT1_ST	P35222	CTNNB1	P31749	AKT1	S23	A21V	21	Missense	proximal	-2	no	11.090	10.352	EPSD	COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	P35222	CTNNB1	P31749	AKT1	S23	A21T	21	Missense	proximal	-2	no	11.090	11.475	EPSD	COSMIC	7.780	Up-regulation
AGC_Akt_AKT1_ST	P35222	CTNNB1	P31749	AKT1	S23	V22I	22	Missense	proximal	-1	no	11.090	11.075	EPSD	COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	P35222	CTNNB1	P31749	AKT1	S23	S29P	29	Missense	distal	6	no	11.090	10.996	EPSD	COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	P35222	CTNNB1	P31749	AKT1	S23	A20V	20	Missense	distal	-3	no	11.090	10.528	EPSD	COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	P35222	CTNNB1	P31749	AKT1	S23	P16T	16	Missense	distal	-7	no	11.090	11.334	EPSD	COSMIC	7.780	Up-regulation
AGC_Akt_AKT1_ST	P35222	CTNNB1	P31749	AKT1	S23	D17H	17	Missense	distal	-6	no	11.090	11.124	EPSD	COSMIC	7.780	Up-regulation
AGC_Akt_AKT1_ST	P35222	CTNNB1	P31749	AKT1	S23	Q27H	27	Missense	distal	4	no	11.090	11.151	EPSD	COSMIC	7.780	Up-regulation
AGC_Akt_AKT1_ST	P35222	CTNNB1	P31749	AKT1	S23	S23N	23	Missense	central	0	yes	11.090	0.000	EPSD	COSMIC	7.780	Loss
AGC_Akt_AKT1_ST	P35222	CTNNB1	P31749	AKT1	S23	S29F	29	Missense	distal	6	no	11.090	10.970	EPSD	COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	P35222	CTNNB1	P31749	AKT1	S23	Y30C	30	Missense	distal	7	no	11.090	11.010	EPSD	COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	P35222	CTNNB1	P31749	AKT1	S23	S29Y	29	Missense	distal	6	no	11.090	11.002	EPSD	COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	P35222	CTNNB1	P31749	AKT1	S23	S23R	23	Missense	central	0	yes	11.090	0.000	EPSD	COSMIC	7.780	Loss
AGC_Akt_AKT1_ST	P35222	CTNNB1	P31749	AKT1	S23	H24Y	24	Missense	proximal	1	no	11.090	11.260	EPSD	COSMIC	7.780	Up-regulation
AGC_Akt_AKT1_ST	P35222	CTNNB1	P31749	AKT1	S23	W25R	25	Missense	proximal	2	no	11.090	11.545	EPSD	COSMIC	7.780	Up-regulation
AGC_Akt_AKT1_ST	P35222	CTNNB1	P31749	AKT1	S23	V22A	22	Missense	proximal	-1	no	11.090	11.104	EPSD	COSMIC	7.780	Up-regulation
AGC_Akt_AKT1_ST	P35222	CTNNB1	P31749	AKT1	S23	W25L	25	Missense	proximal	2	no	11.090	11.172	EPSD	COSMIC	7.780	Up-regulation
AGC_Akt_AKT1_ST	P35222	CTNNB1	P31749	AKT1	S23	H24Q	24	Missense	proximal	1	no	11.090	11.118	EPSD	COSMIC	7.780	Up-regulation
AGC_Akt_AKT1_ST	P35222	CTNNB1	P31749	AKT1	S23	S23G	23	Missense	central	0	yes	11.090	0.000	EPSD	COSMIC	7.780	Loss
AGC_Akt_AKT1_ST	P35222	CTNNB1	P31749	AKT1	S23	V22G	22	Missense	proximal	-1	no	11.090	11.095	EPSD	COSMIC	7.780	Up-regulation
AGC_Akt_AKT1_ST	P35222	CTNNB1	P31749	AKT1	S23	S29A	29	Missense	distal	6	no	11.090	11.008	EPSD	COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	P35222	CTNNB1	P31749	AKT1	S23	D17Y	17	Missense	distal	-6	no	11.090	11.150	EPSD	COSMIC	7.780	Up-regulation
AGC_Akt_AKT1_ST	P35222	CTNNB1	P31749	AKT1	S23	A21D	21	Missense	proximal	-2	no	11.090	10.149	EPSD	COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	P35222	CTNNB1	P31749	AKT1	S23	P16L	16	Missense	distal	-7	no	11.090	11.050	EPSD	COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	P35222	CTNNB1	P31749	AKT1	S23	Y30S	30	Missense	distal	7	no	11.090	11.133	EPSD	COSMIC	7.780	Up-regulation
AGC_Akt_AKT1_ST	P35222	CTNNB1	P31749	AKT1	S23	H24R	24	Missense	proximal	1	no	11.090	11.413	EPSD	COSMIC	7.780	Up-regulation
AGC_Akt_AKT1_ST	P35222	CTNNB1	P31749	AKT1	S23	Q26R	26	Missense	distal	3	no	11.090	11.146	EPSD	COSMIC;GDSC;CCLE	7.780	Up-regulation
AGC_Akt_AKT1_ST	P35222	CTNNB1	P31749	AKT1	S23	R18K	18	Missense	distal	-5	no	11.090	8.693	EPSD	COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	P35222	CTNNB1	P31749	AKT1	S23	Q28R	28	Missense	distal	5	no	11.090	11.141	EPSD	COSMIC	7.780	Up-regulation
AGC_Akt_AKT1_ST	P35222	CTNNB1	P31749	AKT1	S23	P16S	16	Missense	distal	-7	no	11.090	11.284	EPSD	COSMIC	7.780	Up-regulation
AGC_Akt_AKT1_ST	P35222	CTNNB1	P31749	AKT1	S23	A20T	20	Missense	distal	-3	no	11.090	10.371	EPSD	COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	P35222	CTNNB1	P31749	AKT1	S23	S29T	29	Missense	distal	6	no	11.090	11.111	EPSD	COSMIC	7.780	Up-regulation
AGC_Akt_AKT1_ST	P35222	CTNNB1	P31749	AKT1	S23	K19D	19	Missense	distal	-4	no	11.090	9.730	EPSD	COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	P35222	CTNNB1	P31749	AKT1	S29	Q26R	26	Missense	distal	-3	no	4.155	11.366	EPSD	COSMIC;GDSC;CCLE	7.780	Gain
AGC_Akt_AKT1_ST	P35222	CTNNB1	P31749	AKT1	T41	H36R	36	Missense	distal	-5	no	6.156	9.250	EPSD	COSMIC	7.780	Gain
AGC_Akt_AKT1_ST	P35222	CTNNB1	P31749	AKT1	S45	T42R	42	Missense	distal	-3	no	6.410	13.432	EPSD	COSMIC	7.780	Gain
AGC_Akt_AKT1_ST	P35222	CTNNB1	P31749	AKT1	S45	T42K	42	Missense	distal	-3	no	6.410	8.912	EPSD	COSMIC	7.780	Gain
AGC_Akt_AKT1_ST	P35222	CTNNB1	P31749	AKT1	S47	T42R	42	Missense	distal	-5	no	5.040	8.769	EPSD	COSMIC	7.780	Gain
AGC_Akt_AKT1_ST	P35222	CTNNB1	P31749	AKT1	S129	Q130H	130	Missense	proximal	1	no	8.080	8.052	EPSD	COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	P35222	CTNNB1	P31749	AKT1	S129	K133M	133	Missense	distal	4	no	8.080	8.266	EPSD	COSMIC	7.780	Up-regulation
AGC_Akt_AKT1_ST	P35222	CTNNB1	P31749	AKT1	S129	V122G	122	Missense	distal	-7	no	8.080	8.171	EPSD	COSMIC	7.780	Up-regulation
AGC_Akt_AKT1_ST	P35222	CTNNB1	P31749	AKT1	S179	H176R	176	Missense	distal	-3	no	4.924	9.623	EPSD	COSMIC	7.780	Gain
AGC_Akt_AKT1_ST	P35222	CTNNB1	P31749	AKT1	T217	T214A	214	Missense	distal	-3	no	7.095	7.814	EPSD	COSMIC	7.780	Gain
AGC_Akt_AKT1_ST	P35222	CTNNB1	P31749	AKT1	T332	V325I	325	Missense	distal	-7	no	11.856	11.761	EPSD	COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	P35222	CTNNB1	P31749	AKT1	T332	L336V	336	Missense	distal	4	no	11.856	11.847	EPSD	COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	P35222	CTNNB1	P31749	AKT1	T332	I327T	327	Missense	distal	-5	no	11.856	12.693	EPSD	COSMIC	7.780	Up-regulation
AGC_Akt_AKT1_ST	P35222	CTNNB1	P31749	AKT1	T332	I327V	327	Missense	distal	-5	no	11.856	12.108	EPSD	COSMIC	7.780	Up-regulation
AGC_Akt_AKT1_ST	P35222	CTNNB1	P31749	AKT1	T332	K335R	335	Missense	distal	3	no	11.856	11.837	EPSD	COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	P35222	CTNNB1	P31749	AKT1	T332	K335Q	335	Missense	distal	3	no	11.856	11.781	EPSD	COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	P35222	CTNNB1	P31749	AKT1	T332	L337P	337	Missense	distal	5	no	11.856	11.869	EPSD	COSMIC	7.780	Up-regulation
AGC_Akt_AKT1_ST	P35222	CTNNB1	P31749	AKT1	T472	E479K	479	Missense	distal	7	no	10.054	10.087	EPSD	COSMIC	7.780	Up-regulation
AGC_Akt_AKT1_ST	P35222	CTNNB1	P31749	AKT1	T472	L468V	468	Missense	distal	-4	no	10.054	10.084	EPSD	COSMIC	7.780	Up-regulation
AGC_Akt_AKT1_ST	P35222	CTNNB1	P31749	AKT1	T472	A478T	478	Missense	distal	6	no	10.054	10.156	EPSD	COSMIC	7.780	Up-regulation
AGC_Akt_AKT1_ST	P35222	CTNNB1	P31749	AKT1	T472	H475Q	475	Missense	distal	3	no	10.054	10.081	EPSD	COSMIC	7.780	Up-regulation
AGC_Akt_AKT1_ST	P35222	CTNNB1	P31749	AKT1	T472	L471Q	471	Missense	proximal	-1	no	10.054	10.060	EPSD	COSMIC	7.780	Up-regulation
AGC_Akt_AKT1_ST	P35222	CTNNB1	P31749	AKT1	T472	R469C	469	Missense	distal	-3	no	10.054	3.880	EPSD	COSMIC	7.780	Loss
AGC_Akt_AKT1_ST	P35222	CTNNB1	P31749	AKT1	T472	A478G	478	Missense	distal	6	no	10.054	10.031	EPSD	COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	P35222	CTNNB1	P31749	AKT1	T547	T551K	551	Missense	distal	4	no	9.356	9.339	EPSD	COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	P35222	CTNNB1	P31749	AKT1	T547	R549C	549	Missense	proximal	2	no	9.356	8.704	EPSD	COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	P35222	CTNNB1	P31749	AKT1	T547	Q545K	545	Missense	proximal	-2	no	9.356	10.308	EPSD	COSMIC	7.780	Up-regulation
AGC_Akt_AKT1_ST	P35222	CTNNB1	P31749	AKT1	T547	A543T	543	Missense	distal	-4	no	9.356	10.134	EPSD	COSMIC	7.780	Up-regulation
AGC_Akt_AKT1_ST	P35222	CTNNB1	P31749	AKT1	T547	R550H	550	Missense	distal	3	no	9.356	9.273	EPSD	COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	P35222	CTNNB1	P31749	AKT1	T547	L540F	540	Missense	distal	-7	no	9.356	9.312	EPSD	COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	P35222	CTNNB1	P31749	AKT1	T547	R550L	550	Missense	distal	3	no	9.356	9.275	EPSD	COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	P35222	CTNNB1	P31749	AKT1	T547	A543V	543	Missense	distal	-4	no	9.356	8.984	EPSD	COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	P35222	CTNNB1	P31749	AKT1	T547	D546E	546	Missense	proximal	-1	no	9.356	9.390	EPSD	COSMIC	7.780	Up-regulation
AGC_Akt_AKT1_ST	P35222	CTNNB1	P31749	AKT1	T547	S552F	552	Missense	distal	5	no	9.356	9.284	EPSD	COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	P35222	CTNNB1	P31749	AKT1	T547	G554D	554	Missense	distal	7	no	9.356	9.353	EPSD	COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	P35222	CTNNB1	P31749	AKT1	T547	R550Q	550	Missense	distal	3	no	9.356	9.300	EPSD	COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	P35222	CTNNB1	P31749	AKT1	T547	T551I	551	Missense	distal	4	no	9.356	9.623	EPSD	COSMIC	7.780	Up-regulation
AGC_Akt_AKT1_ST	P35222	CTNNB1	P31749	AKT1	S552	R549C	549	Missense	distal	-3	no	12.531	6.357	PhosphoSitePlus	COSMIC	7.780	Loss
AGC_Akt_AKT1_ST	P35222	CTNNB1	P31749	AKT1	S552	Q545K	545	Missense	distal	-7	no	12.531	12.712	PhosphoSitePlus	COSMIC	7.780	Up-regulation
AGC_Akt_AKT1_ST	P35222	CTNNB1	P31749	AKT1	S552	Q558H	558	Missense	distal	6	no	12.531	12.482	PhosphoSitePlus	COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	P35222	CTNNB1	P31749	AKT1	S552	G555A	555	Missense	distal	3	no	12.531	12.564	PhosphoSitePlus	COSMIC	7.780	Up-regulation
AGC_Akt_AKT1_ST	P35222	CTNNB1	P31749	AKT1	S552	R550H	550	Missense	proximal	-2	no	12.531	11.670	PhosphoSitePlus	COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	P35222	CTNNB1	P31749	AKT1	S552	R550L	550	Missense	proximal	-2	no	12.531	11.862	PhosphoSitePlus	COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	P35222	CTNNB1	P31749	AKT1	S552	D546E	546	Missense	distal	-6	no	12.531	12.603	PhosphoSitePlus	COSMIC	7.780	Up-regulation
AGC_Akt_AKT1_ST	P35222	CTNNB1	P31749	AKT1	S552	S552F	552	Missense	central	0	yes	12.531	0.000	PhosphoSitePlus	COSMIC	7.780	Loss
AGC_Akt_AKT1_ST	P35222	CTNNB1	P31749	AKT1	S552	T547S	547	Missense	distal	-5	no	12.531	11.790	PhosphoSitePlus	COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	P35222	CTNNB1	P31749	AKT1	S552	G554D	554	Missense	proximal	2	no	12.531	12.264	PhosphoSitePlus	COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	P35222	CTNNB1	P31749	AKT1	S552	R550Q	550	Missense	proximal	-2	no	12.531	12.018	PhosphoSitePlus	COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	P35222	CTNNB1	P31749	AKT1	S552	T551I	551	Missense	proximal	-1	no	12.531	12.475	PhosphoSitePlus	COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	P35222	CTNNB1	P31749	AKT1	S675	R673W	673	Missense	proximal	-2	no	7.903	6.649	EPSD	COSMIC	7.780	Loss
AGC_Akt_AKT1_ST	P35222	CTNNB1	P31749	AKT1	S675	S680I	680	Missense	distal	5	no	7.903	7.806	EPSD	COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	P35222	CTNNB1	P31749	AKT1	S675	E677D	677	Missense	proximal	2	no	7.903	7.493	EPSD	COSMIC	7.780	Loss
AGC_Akt_AKT1_ST	P35222	CTNNB1	P31749	AKT1	S675	R673H	673	Missense	proximal	-2	no	7.903	7.042	EPSD	COSMIC	7.780	Loss
AGC_Akt_AKT1_ST	P35222	CTNNB1	P31749	AKT1	S675	L678F	678	Missense	distal	3	no	7.903	7.902	EPSD	COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	P35222	CTNNB1	P31749	AKT1	S675	R673C	673	Missense	proximal	-2	no	7.903	6.439	EPSD	COSMIC	7.780	Loss
AGC_Akt_AKT1_ST	P35222	CTNNB1	P31749	AKT1	S715	Y716C	716	Missense	proximal	1	no	9.638	9.261	EPSD	COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	P35222	CTNNB1	P31749	AKT1	S715	H720P	720	Missense	distal	5	no	9.638	9.651	EPSD	COSMIC	7.780	Up-regulation
AGC_Akt_AKT1_ST	P35222	CTNNB1	P31749	AKT1	S715	R717C	717	Missense	proximal	2	no	9.638	8.985	EPSD	COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	P35222	CTNNB1	P31749	AKT1	S715	S715R	715	Missense	central	0	yes	9.638	0.000	EPSD	COSMIC	7.780	Loss
AGC_Akt_AKT1_ST	P35222	CTNNB1	P31749	AKT1	S715	D712N	712	Missense	distal	-3	no	9.638	8.112	EPSD	COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	P35222	CTNNB1	P31749	AKT1	S715	P714S	714	Missense	proximal	-1	no	9.638	9.667	EPSD	COSMIC	7.780	Up-regulation
AGC_Akt_AKT1_ST	P35222	CTNNB1	P31749	AKT1	S715	Y709C	709	Missense	distal	-6	no	9.638	9.550	EPSD	COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	P35222	CTNNB1	P31749	AKT1	S715	R710C	710	Missense	distal	-5	no	9.638	5.561	EPSD	COSMIC	7.780	Loss
AGC_Akt_AKT1_ST	P35222	CTNNB1	P31749	AKT1	S718	S715R	715	Missense	distal	-3	no	4.675	12.452	EPSD	COSMIC	7.780	Gain
AGC_Akt_AKT1_ST	P54274	TERF1	P31749	AKT1	T271	S274Y	274	Missense	distal	3	no	10.789	10.720	EPSD	COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	P54274	TERF1	P31749	AKT1	T273	S274Y	274	Missense	proximal	1	no	15.133	15.126	PhosphoSitePlus	COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	P54274	TERF1	P31749	AKT1	T344	T348K	348	Missense	distal	4	no	10.990	10.972	EPSD	COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	P54274	TERF1	P31749	AKT1	T344	P345H	345	Missense	proximal	1	no	10.990	10.967	EPSD	COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	P54274	TERF1	P31749	AKT1	T344	S347R	347	Missense	distal	3	no	10.990	10.973	EPSD	COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	P54274	TERF1	P31749	AKT1	T358	A357S	357	Missense	proximal	-1	no	12.453	12.474	EPSD	COSMIC	7.780	Up-regulation
AGC_Akt_AKT1_ST	P54274	TERF1	P31749	AKT1	T358	P363A	363	Missense	distal	5	no	12.453	12.455	EPSD	COSMIC	7.780	Up-regulation
AGC_Akt_AKT1_ST	P54274	TERF1	P31749	AKT1	T358	S354I	354	Missense	distal	-4	no	12.453	11.071	EPSD	COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	P54274	TERF1	P31749	AKT1	T358	A357D	357	Missense	proximal	-1	no	12.453	12.426	EPSD	COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	P54274	TERF1	P31749	AKT1	S434	S434C	434	Missense	central	0	yes	9.370	0.000	EPSD	COSMIC	7.780	Loss
AGC_Akt_AKT1_ST	P54274	TERF1	P31749	AKT1	S434	I433N	433	Missense	proximal	-1	no	9.370	9.401	EPSD	COSMIC	7.780	Up-regulation
AGC_Akt_AKT1_ST	Q86VP3	PACS2	P31749	AKT1	S43	R40S	40	Missense	distal	-3	no	11.944	4.167	EPSD	COSMIC	7.780	Loss
AGC_Akt_AKT1_ST	Q86VP3	PACS2	P31749	AKT1	T125	I126F	126	Missense	proximal	1	no	10.903	11.170	EPSD	COSMIC	7.780	Up-regulation
AGC_Akt_AKT1_ST	Q86VP3	PACS2	P31749	AKT1	T125	R120C	120	Missense	distal	-5	no	10.903	6.826	EPSD	COSMIC	7.780	Loss
AGC_Akt_AKT1_ST	Q86VP3	PACS2	P31749	AKT1	T242	S244F	244	Missense	proximal	2	no	8.663	8.085	EPSD	COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	Q86VP3	PACS2	P31749	AKT1	S244	S244F	244	Missense	central	0	yes	12.671	0.000	EPSD	COSMIC	7.780	Loss
AGC_Akt_AKT1_ST	Q86VP3	PACS2	P31749	AKT1	T246	K252N	252	Missense	distal	6	no	8.830	8.752	EPSD	COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	Q86VP3	PACS2	P31749	AKT1	T246	S244F	244	Missense	proximal	-2	no	8.830	7.963	EPSD	COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	Q86VP3	PACS2	P31749	AKT1	S366	T372M	372	Missense	distal	6	no	11.282	11.163	EPSD	COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	Q86VP3	PACS2	P31749	AKT1	S366	P365L	365	Missense	proximal	-1	no	11.282	11.283	EPSD	COSMIC	7.780	Up-regulation
AGC_Akt_AKT1_ST	Q86VP3	PACS2	P31749	AKT1	S366	S366P	366	Missense	central	0	yes	11.282	0.000	EPSD	COSMIC	7.780	Loss
AGC_Akt_AKT1_ST	Q86VP3	PACS2	P31749	AKT1	S368	T372M	372	Missense	distal	4	no	8.837	9.006	EPSD	COSMIC	7.780	Up-regulation
AGC_Akt_AKT1_ST	Q86VP3	PACS2	P31749	AKT1	S368	P365L	365	Missense	distal	-3	no	8.837	8.483	EPSD	COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	Q86VP3	PACS2	P31749	AKT1	S368	S366P	366	Missense	proximal	-2	no	8.837	8.013	EPSD	COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	Q86VP3	PACS2	P31749	AKT1	S416	V418F	418	Missense	proximal	2	no	7.792	7.752	EPSD	COSMIC	7.780	Loss
AGC_Akt_AKT1_ST	Q86VP3	PACS2	P31749	AKT1	S416	L417I	417	Missense	proximal	1	no	7.792	7.445	EPSD	COSMIC	7.780	Loss
AGC_Akt_AKT1_ST	Q86VP3	PACS2	P31749	AKT1	S435	R441W	441	Missense	distal	6	no	12.145	11.986	EPSD	COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	Q86VP3	PACS2	P31749	AKT1	S435	R432Q	432	Missense	distal	-3	no	12.145	4.933	EPSD	COSMIC;CCLE	7.780	Loss
AGC_Akt_AKT1_ST	Q86VP3	PACS2	P31749	AKT1	S435	S435G	435	Missense	central	0	yes	12.145	0.000	EPSD	COSMIC	7.780	Loss
AGC_Akt_AKT1_ST	Q86VP3	PACS2	P31749	AKT1	S435	R434Q	434	Missense	proximal	-1	no	12.145	12.112	EPSD	COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	Q86VP3	PACS2	P31749	AKT1	T436	R441W	441	Missense	distal	5	no	8.417	8.322	EPSD	COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	Q86VP3	PACS2	P31749	AKT1	T436	R432Q	432	Missense	distal	-4	no	8.417	7.796	EPSD	COSMIC;CCLE	7.780	Down-regulation
AGC_Akt_AKT1_ST	Q86VP3	PACS2	P31749	AKT1	T436	S435G	435	Missense	proximal	-1	no	8.417	8.387	EPSD	COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	Q86VP3	PACS2	P31749	AKT1	T436	R434Q	434	Missense	proximal	-2	no	8.417	7.904	EPSD	COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	Q86VP3	PACS2	P31749	AKT1	S437	R441W	441	Missense	distal	4	no	15.176	15.423	PhosphoSitePlus	COSMIC	7.780	Up-regulation
AGC_Akt_AKT1_ST	Q86VP3	PACS2	P31749	AKT1	S437	R432Q	432	Missense	distal	-5	no	15.176	10.948	PhosphoSitePlus	COSMIC;CCLE	7.780	Down-regulation
AGC_Akt_AKT1_ST	Q86VP3	PACS2	P31749	AKT1	S437	S435G	435	Missense	proximal	-2	no	15.176	14.481	PhosphoSitePlus	COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	Q86VP3	PACS2	P31749	AKT1	S437	R434Q	434	Missense	distal	-3	no	15.176	7.964	PhosphoSitePlus	COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	Q86VP3	PACS2	P31749	AKT1	S453	P460L	460	Missense	distal	7	no	10.559	10.551	EPSD	COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	Q86VP3	PACS2	P31749	AKT1	S453	S453I	453	Missense	central	0	yes	10.559	0.000	EPSD	COSMIC	7.780	Loss
AGC_Akt_AKT1_ST	Q86VP3	PACS2	P31749	AKT1	S453	A451T	451	Missense	proximal	-2	no	10.559	10.945	EPSD	COSMIC	7.780	Up-regulation
AGC_Akt_AKT1_ST	Q86VP3	PACS2	P31749	AKT1	T704	G701R	701	Missense	distal	-3	no	4.822	11.578	EPSD	COSMIC	7.780	Gain
AGC_Akt_AKT1_ST	Q86VP3	PACS2	P31749	AKT1	S706	G701R	701	Missense	distal	-5	no	5.235	9.299	EPSD	COSMIC	7.780	Gain
AGC_Akt_AKT1_ST	Q86VP3	PACS2	P31749	AKT1	S720	P714H	714	Missense	distal	-6	no	8.182	8.161	EPSD	COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	Q86VP3	PACS2	P31749	AKT1	S720	T722M	722	Missense	proximal	2	no	8.182	7.840	EPSD	COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	Q86VP3	PACS2	P31749	AKT1	S720	A719D	719	Missense	proximal	-1	no	8.182	8.155	EPSD	COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	Q86VP3	PACS2	P31749	AKT1	S720	S726F	726	Missense	distal	6	no	8.182	8.062	EPSD	COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	Q86VP3	PACS2	P31749	AKT1	S720	P714S	714	Missense	distal	-6	no	8.182	8.246	EPSD	COSMIC	7.780	Up-regulation
AGC_Akt_AKT1_ST	Q86VP3	PACS2	P31749	AKT1	S786	P789H	789	Missense	distal	3	no	8.435	8.417	EPSD	COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	Q86VP3	PACS2	P31749	AKT1	S786	R781Q	781	Missense	distal	-5	no	8.435	4.208	EPSD	COSMIC	7.780	Loss
AGC_Akt_AKT1_ST	Q86VP3	PACS2	P31749	AKT1	S790	P789H	789	Missense	proximal	-1	no	10.861	10.856	EPSD	COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	Q86VP3	PACS2	P31749	AKT1	S790	T797M	797	Missense	distal	7	no	10.861	10.792	EPSD	COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	Q86VP3	PACS2	P31749	AKT1	S790	A794D	794	Missense	distal	4	no	10.861	10.961	EPSD	COSMIC	7.780	Up-regulation
AGC_Akt_AKT1_ST	Q99490	AGAP2	P31749	AKT1	S523	R525Q	525	Missense	proximal	2	no	8.050	7.932	EPSD	COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	Q99490	AGAP2	P31749	AKT1	S648	A651V	651	Missense	distal	3	no	13.167	13.135	EPSD	COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	Q99490	AGAP2	P31749	AKT1	S648	R654Q	654	Missense	distal	6	no	13.167	13.096	EPSD	COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	Q99490	AGAP2	P31749	AKT1	S648	A642T	642	Missense	distal	-6	no	13.167	13.253	EPSD	COSMIC	7.780	Up-regulation
AGC_Akt_AKT1_ST	Q99490	AGAP2	P31749	AKT1	S648	R653H	653	Missense	distal	5	no	13.167	13.093	EPSD	COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	Q99490	AGAP2	P31749	AKT1	S648	R641Q	641	Missense	distal	-7	no	13.167	12.972	EPSD	COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	Q99490	AGAP2	P31749	AKT1	S648	R654W	654	Missense	distal	6	no	13.167	13.009	EPSD	COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	Q99490	AGAP2	P31749	AKT1	S648	R654G	654	Missense	distal	6	no	13.167	13.063	EPSD	COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	Q99490	AGAP2	P31749	AKT1	S656	A651V	651	Missense	distal	-5	no	11.284	10.824	EPSD	COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	Q99490	AGAP2	P31749	AKT1	S656	D657A	657	Missense	proximal	1	no	11.284	11.424	EPSD	COSMIC	7.780	Up-regulation
AGC_Akt_AKT1_ST	Q99490	AGAP2	P31749	AKT1	S656	R654Q	654	Missense	proximal	-2	no	11.284	10.772	EPSD	COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	Q99490	AGAP2	P31749	AKT1	S656	R653H	653	Missense	distal	-3	no	11.284	6.586	EPSD	COSMIC	7.780	Loss
AGC_Akt_AKT1_ST	Q99490	AGAP2	P31749	AKT1	S656	R654W	654	Missense	proximal	-2	no	11.284	10.030	EPSD	COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	Q99490	AGAP2	P31749	AKT1	S656	R654G	654	Missense	proximal	-2	no	11.284	10.778	EPSD	COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	Q99490	AGAP2	P31749	AKT1	S745	S750P	750	Missense	distal	5	no	10.502	10.449	EPSD	COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	Q99490	AGAP2	P31749	AKT1	S745	R739W	739	Missense	distal	-6	no	10.502	10.355	EPSD	COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	Q99490	AGAP2	P31749	AKT1	S745	S745F	745	Missense	central	0	yes	10.502	0.000	EPSD	COSMIC	7.780	Loss
AGC_Akt_AKT1_ST	Q99490	AGAP2	P31749	AKT1	S808	A804P	804	Missense	distal	-4	no	11.078	11.064	EPSD	COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	Q99490	AGAP2	P31749	AKT1	S808	R801W	801	Missense	distal	-7	no	11.078	10.655	EPSD	COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	Q99490	AGAP2	P31749	AKT1	T839	R834K	834	Missense	distal	-5	no	11.095	8.698	EPSD	COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	Q99490	AGAP2	P31749	AKT1	T839	K836N	836	Missense	distal	-3	no	11.095	8.138	EPSD	COSMIC;GDSC;CCLE	7.780	Down-regulation
AGC_Akt_AKT1_ST	Q99490	AGAP2	P31749	AKT1	S985	D990E	990	Missense	distal	5	no	11.831	11.873	EPSD	COSMIC;GDSC	7.780	Up-regulation
AGC_Akt_AKT1_ST	Q99490	AGAP2	P31749	AKT1	S985	R982C	982	Missense	distal	-3	no	11.831	5.657	EPSD	COSMIC	7.780	Loss
AGC_Akt_AKT1_ST	Q8N6T7	SIRT6	P31749	AKT1	T167	R164Q	164	Missense	distal	-3	no	10.227	3.015	EPSD	COSMIC	7.780	Loss
AGC_Akt_AKT1_ST	Q8N6T7	SIRT6	P31749	AKT1	T167	T162I	162	Missense	distal	-5	no	10.227	9.389	EPSD	COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	Q8N6T7	SIRT6	P31749	AKT1	T294	P292L	292	Missense	proximal	-2	no	10.514	10.482	EPSD	COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	Q8N6T7	SIRT6	P31749	AKT1	T337	R333P	333	Missense	distal	-4	no	7.818	6.996	EPSD	COSMIC	7.780	Loss
AGC_Akt_AKT1_ST	Q8N6T7	SIRT6	P31749	AKT1	S338	R333P	333	Missense	distal	-5	no	17.700	13.690	PhosphoSitePlus	COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	O14746	TERT	P31749	AKT1	S227	R224C	224	Missense	distal	-3	no	16.135	9.962	PhosphoSitePlus;EPSD	COSMIC;CCLE	7.780	Down-regulation
AGC_Akt_AKT1_ST	O14746	TERT	P31749	AKT1	S227	G225E	225	Missense	proximal	-2	no	16.135	16.422	PhosphoSitePlus;EPSD	COSMIC	7.780	Up-regulation
AGC_Akt_AKT1_ST	O14746	TERT	P31749	AKT1	S227	L234F	234	Missense	distal	7	no	16.135	16.128	PhosphoSitePlus;EPSD	COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	O14746	TERT	P31749	AKT1	S227	R224H	224	Missense	distal	-3	no	16.135	11.437	PhosphoSitePlus;EPSD	COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	O14746	TERT	P31749	AKT1	S227	L232V	232	Missense	distal	5	no	16.135	16.142	PhosphoSitePlus;EPSD	COSMIC	7.780	Up-regulation
AGC_Akt_AKT1_ST	O14746	TERT	P31749	AKT1	T618	E611K	611	Missense	distal	-7	no	8.229	8.422	EPSD	COSMIC	7.780	Up-regulation
AGC_Akt_AKT1_ST	O14746	TERT	P31749	AKT1	T618	A615T	615	Missense	distal	-3	no	8.229	7.510	EPSD	COSMIC	7.780	Loss
AGC_Akt_AKT1_ST	O14746	TERT	P31749	AKT1	T618	R613S	613	Missense	distal	-5	no	8.229	3.759	EPSD	COSMIC	7.780	Loss
AGC_Akt_AKT1_ST	O14746	TERT	P31749	AKT1	T618	S619F	619	Missense	proximal	1	no	8.229	8.247	EPSD	COSMIC	7.780	Up-regulation
AGC_Akt_AKT1_ST	O14746	TERT	P31749	AKT1	S824	V826I	826	Missense	proximal	2	no	14.874	14.756	EPSD;PhosphoSitePlus	COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	O14746	TERT	P31749	AKT1	S824	K823R	823	Missense	proximal	-1	no	14.874	14.878	EPSD;PhosphoSitePlus	COSMIC	7.780	Up-regulation
AGC_Akt_AKT1_ST	O14746	TERT	P31749	AKT1	S824	R819H	819	Missense	distal	-5	no	14.874	11.780	EPSD;PhosphoSitePlus	COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	O14746	TERT	P31749	AKT1	S824	G822C	822	Missense	proximal	-2	no	14.874	13.917	EPSD;PhosphoSitePlus	COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	O14746	TERT	P31749	AKT1	S824	G822D	822	Missense	proximal	-2	no	14.874	14.176	EPSD;PhosphoSitePlus	COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	O14746	TERT	P31749	AKT1	S824	A817V	817	Missense	distal	-7	no	14.874	14.746	EPSD;PhosphoSitePlus	COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	O14746	TERT	P31749	AKT1	S984	D988N	988	Missense	distal	4	no	8.560	8.445	EPSD	COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	O14746	TERT	P31749	AKT1	S984	V977L	977	Missense	distal	-7	no	8.560	8.604	EPSD	COSMIC	7.780	Up-regulation
AGC_Akt_AKT1_ST	P21453	S1PR1	P31749	AKT1	T236	R238L	238	Missense	proximal	2	no	16.477	16.104	PhosphoSitePlus	COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	P21453	S1PR1	P31749	AKT1	T236	R233C	233	Missense	distal	-3	no	16.477	10.304	PhosphoSitePlus	COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	P21453	S1PR1	P31749	AKT1	T236	R234S	234	Missense	proximal	-2	no	16.477	16.666	PhosphoSitePlus	COSMIC;GDSC;CCLE	7.780	Up-regulation
AGC_Akt_AKT1_ST	P21453	S1PR1	P31749	AKT1	T236	T230A	230	Missense	distal	-6	no	16.477	16.391	PhosphoSitePlus	COSMIC;CCLE	7.780	Down-regulation
AGC_Akt_AKT1_ST	P21453	S1PR1	P31749	AKT1	T236	R238H	238	Missense	proximal	2	no	16.477	16.116	PhosphoSitePlus	COSMIC;GDSC	7.780	Down-regulation
AGC_Akt_AKT1_ST	P21453	S1PR1	P31749	AKT1	S355	M348V	348	Missense	distal	-7	no	13.849	13.787	EPSD	COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	P21453	S1PR1	P31749	AKT1	S355	R352L	352	Missense	distal	-3	no	13.849	6.855	EPSD	COSMIC	7.780	Loss
AGC_Akt_AKT1_ST	P21453	S1PR1	P31749	AKT1	S355	P361R	361	Missense	distal	6	no	13.849	13.941	EPSD	COSMIC	7.780	Up-regulation
AGC_Akt_AKT1_ST	P21453	S1PR1	P31749	AKT1	S355	H360N	360	Missense	distal	5	no	13.849	13.881	EPSD	COSMIC;CCLE	7.780	Up-regulation
AGC_Akt_AKT1_ST	P21453	S1PR1	P31749	AKT1	S355	D356Y	356	Missense	proximal	1	no	13.849	14.055	EPSD	COSMIC	7.780	Up-regulation
AGC_Akt_AKT1_ST	P21453	S1PR1	P31749	AKT1	S355	S359F	359	Missense	distal	4	no	13.849	14.045	EPSD	COSMIC	7.780	Up-regulation
AGC_Akt_AKT1_ST	P21453	S1PR1	P31749	AKT1	S355	E349Q	349	Missense	distal	-6	no	13.849	13.845	EPSD	COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	P21453	S1PR1	P31749	AKT1	S355	K354E	354	Missense	proximal	-1	no	13.849	13.828	EPSD	COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	P46937	YAP1	P31749	AKT1	S61	E62D	62	Missense	proximal	1	no	11.635	11.517	EPSD	COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	P46937	YAP1	P31749	AKT1	T63	E62D	62	Missense	proximal	-1	no	8.987	8.953	EPSD	COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	P46937	YAP1	P31749	AKT1	S105	R106G	106	Missense	proximal	1	no	8.034	7.584	EPSD	COSMIC	7.780	Loss
AGC_Akt_AKT1_ST	P46937	YAP1	P31749	AKT1	S105	S105P	105	Missense	central	0	yes	8.034	0.000	EPSD	COSMIC	7.780	Loss
AGC_Akt_AKT1_ST	P46937	YAP1	P31749	AKT1	S105	K102R	102	Missense	distal	-3	no	8.034	12.554	EPSD	COSMIC	7.780	Up-regulation
AGC_Akt_AKT1_ST	P46937	YAP1	P31749	AKT1	S109	R106G	106	Missense	distal	-3	no	13.488	6.732	EPSD	COSMIC	7.780	Loss
AGC_Akt_AKT1_ST	P46937	YAP1	P31749	AKT1	S109	S105P	105	Missense	distal	-4	no	13.488	12.752	EPSD	COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	P46937	YAP1	P31749	AKT1	S109	K102R	102	Missense	distal	-7	no	13.488	13.502	EPSD	COSMIC	7.780	Up-regulation
AGC_Akt_AKT1_ST	P46937	YAP1	P31749	AKT1	S127	L132R	132	Missense	distal	5	no	11.042	11.116	PhosphoSitePlus	COSMIC	7.780	Up-regulation
AGC_Akt_AKT1_ST	P46937	YAP1	P31749	AKT1	S127	Q133H	133	Missense	distal	6	no	11.042	10.993	PhosphoSitePlus	COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	P46937	YAP1	P31749	AKT1	S127	S127F	127	Missense	central	0	yes	11.042	0.000	PhosphoSitePlus	COSMIC	7.780	Loss
AGC_Akt_AKT1_ST	P46937	YAP1	P31749	AKT1	S127	A125G	125	Missense	proximal	-2	no	11.042	10.799	PhosphoSitePlus	COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	P46937	YAP1	P31749	AKT1	S164	D170N	170	Missense	distal	6	no	11.562	11.644	EPSD	COSMIC	7.780	Up-regulation
AGC_Akt_AKT1_ST	P46937	YAP1	P31749	AKT1	S164	I167T	167	Missense	distal	3	no	11.562	11.692	EPSD	COSMIC	7.780	Up-regulation
AGC_Akt_AKT1_ST	P46937	YAP1	P31749	AKT1	S164	Q162R	162	Missense	proximal	-2	no	11.562	12.075	EPSD	COSMIC	7.780	Up-regulation
AGC_Akt_AKT1_ST	P46937	YAP1	P31749	AKT1	S164	L160H	160	Missense	distal	-4	no	11.562	11.713	EPSD	COSMIC	7.780	Up-regulation
AGC_Akt_AKT1_ST	P46937	YAP1	P31749	AKT1	S164	E166G	166	Missense	proximal	2	no	11.562	11.419	EPSD	COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	P46937	YAP1	P31749	AKT1	S257	L259R	259	Missense	proximal	2	no	9.146	9.519	EPSD	COSMIC	7.780	Up-regulation
AGC_Akt_AKT1_ST	P46937	YAP1	P31749	AKT1	S336	A338T	338	Missense	proximal	2	no	7.534	7.835	EPSD	COSMIC	7.780	Gain
AGC_Akt_AKT1_ST	P46937	YAP1	P31749	AKT1	T378	N380T	380	Missense	proximal	2	no	9.656	9.851	EPSD	COSMIC	7.780	Up-regulation
AGC_Akt_AKT1_ST	P46937	YAP1	P31749	AKT1	T378	S382C	382	Missense	distal	4	no	9.656	10.001	EPSD	COSMIC	7.780	Up-regulation
AGC_Akt_AKT1_ST	P46937	YAP1	P31749	AKT1	T378	D383H	383	Missense	distal	5	no	9.656	9.665	EPSD	COSMIC	7.780	Up-regulation
AGC_Akt_AKT1_ST	P46937	YAP1	P31749	AKT1	T378	T378I	378	Missense	central	0	yes	9.656	0.000	EPSD	COSMIC	7.780	Loss
AGC_Akt_AKT1_ST	P46937	YAP1	P31749	AKT1	T378	S371F	371	Missense	distal	-7	no	9.656	9.379	EPSD	COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	P46937	YAP1	P31749	AKT1	T378	D383G	383	Missense	distal	5	no	9.656	9.668	EPSD	COSMIC	7.780	Up-regulation
AGC_Akt_AKT1_ST	P46937	YAP1	P31749	AKT1	T378	S382T	382	Missense	distal	4	no	9.656	9.651	EPSD	COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	P46937	YAP1	P31749	AKT1	T378	F385L	385	Missense	distal	7	no	9.656	9.664	EPSD	COSMIC	7.780	Up-regulation
AGC_Akt_AKT1_ST	P46937	YAP1	P31749	AKT1	T378	T376A	376	Missense	proximal	-2	no	9.656	9.271	EPSD	COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	P46937	YAP1	P31749	AKT1	T378	T376P	376	Missense	proximal	-2	no	9.656	8.899	EPSD	COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	P46937	YAP1	P31749	AKT1	T378	T378M	378	Missense	central	0	yes	9.656	0.000	EPSD	COSMIC	7.780	Loss
AGC_Akt_AKT1_ST	P46937	YAP1	P31749	AKT1	T378	M377V	377	Missense	proximal	-1	no	9.656	9.651	EPSD	COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	P46937	YAP1	P31749	AKT1	T378	M377I	377	Missense	proximal	-1	no	9.656	9.636	EPSD	COSMIC;GDSC;CCLE	7.780	Down-regulation
AGC_Akt_AKT1_ST	P46937	YAP1	P31749	AKT1	S397	D399G	399	Missense	proximal	2	no	12.580	12.847	EPSD	COSMIC	7.780	Up-regulation
AGC_Akt_AKT1_ST	P46937	YAP1	P31749	AKT1	S397	T390I	390	Missense	distal	-7	no	12.580	12.157	EPSD	COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	P46937	YAP1	P31749	AKT1	S397	E396K	396	Missense	proximal	-1	no	12.580	12.601	EPSD	COSMIC	7.780	Up-regulation
AGC_Akt_AKT1_ST	P46937	YAP1	P31749	AKT1	S397	D399H	399	Missense	proximal	2	no	12.580	12.646	EPSD	COSMIC	7.780	Up-regulation
AGC_Akt_AKT1_ST	P46937	YAP1	P31749	AKT1	S397	D395G	395	Missense	proximal	-2	no	12.580	13.278	EPSD	COSMIC	7.780	Up-regulation
AGC_Akt_AKT1_ST	P46937	YAP1	P31749	AKT1	S499	L501I	501	Missense	proximal	2	no	9.760	9.649	EPSD	COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	Q9H9Q4	NHEJ1	P31749	AKT1	T181	S188F	188	Missense	distal	7	no	13.742	13.669	PhosphoSitePlus	COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	Q9H9Q4	NHEJ1	P31749	AKT1	T181	D177Y	177	Missense	distal	-4	no	13.742	14.171	PhosphoSitePlus	COSMIC	7.780	Up-regulation
AGC_Akt_AKT1_ST	Q9NWV8	BABAM1	P31749	AKT1	S116	G115S	115	Missense	proximal	-1	no	8.098	8.128	EPSD	COSMIC	7.780	Up-regulation
AGC_Akt_AKT1_ST	Q9NWV8	BABAM1	P31749	AKT1	S116	S112L	112	Missense	distal	-4	no	8.098	6.974	EPSD	COSMIC;GDSC;CCLE	7.780	Loss
AGC_Akt_AKT1_ST	Q86TI0	TBC1D1	P31749	AKT1	S235	R230M	230	Missense	distal	-5	no	8.951	4.429	EPSD	COSMIC;GDSC;CCLE	7.780	Loss
AGC_Akt_AKT1_ST	Q86TI0	TBC1D1	P31749	AKT1	S235	R230K	230	Missense	distal	-5	no	8.951	6.554	EPSD	COSMIC	7.780	Loss
AGC_Akt_AKT1_ST	Q86TI0	TBC1D1	P31749	AKT1	S235	S237F	237	Missense	proximal	2	no	8.951	8.374	EPSD	COSMIC;GDSC;CCLE	7.780	Down-regulation
AGC_Akt_AKT1_ST	Q86TI0	TBC1D1	P31749	AKT1	S237	R230M	230	Missense	distal	-7	no	9.224	8.952	EPSD	COSMIC;GDSC;CCLE	7.780	Down-regulation
AGC_Akt_AKT1_ST	Q86TI0	TBC1D1	P31749	AKT1	S237	S243L	243	Missense	distal	6	no	9.224	9.121	EPSD	COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	Q86TI0	TBC1D1	P31749	AKT1	S237	R230K	230	Missense	distal	-7	no	9.224	9.211	EPSD	COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	Q86TI0	TBC1D1	P31749	AKT1	S237	S237F	237	Missense	central	0	yes	9.224	0.000	EPSD	COSMIC;GDSC;CCLE	7.780	Loss
AGC_Akt_AKT1_ST	Q86TI0	TBC1D1	P31749	AKT1	T294	V300I	300	Missense	distal	6	no	8.234	8.183	EPSD	COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	Q86TI0	TBC1D1	P31749	AKT1	T294	S298Y	298	Missense	distal	4	no	8.234	8.370	EPSD	COSMIC	7.780	Up-regulation
AGC_Akt_AKT1_ST	Q86TI0	TBC1D1	P31749	AKT1	T505	S507F	507	Missense	proximal	2	no	12.351	11.773	EPSD	COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	Q86TI0	TBC1D1	P31749	AKT1	T505	R502T	502	Missense	distal	-3	no	12.351	5.329	EPSD	COSMIC;GDSC;CCLE	7.780	Loss
AGC_Akt_AKT1_ST	Q86TI0	TBC1D1	P31749	AKT1	S507	S507F	507	Missense	central	0	yes	9.996	0.000	EPSD	COSMIC	7.780	Loss
AGC_Akt_AKT1_ST	Q86TI0	TBC1D1	P31749	AKT1	S507	R502T	502	Missense	distal	-5	no	9.996	6.266	EPSD	COSMIC;GDSC;CCLE	7.780	Loss
AGC_Akt_AKT1_ST	Q86TI0	TBC1D1	P31749	AKT1	S527	E523K	523	Missense	distal	-4	no	7.920	8.504	EPSD	COSMIC	7.780	Up-regulation
AGC_Akt_AKT1_ST	Q86TI0	TBC1D1	P31749	AKT1	S627	Y625C	625	Missense	proximal	-2	no	11.603	10.872	EPSD	COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	Q86TI0	TBC1D1	P31749	AKT1	S627	T632A	632	Missense	distal	5	no	11.603	11.551	EPSD	COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	Q86TI0	TBC1D1	P31749	AKT1	S627	R624G	624	Missense	distal	-3	no	11.603	4.847	EPSD	COSMIC	7.780	Loss
AGC_Akt_AKT1_ST	Q86TI0	TBC1D1	P31749	AKT1	S629	Y625C	625	Missense	distal	-4	no	11.727	10.994	EPSD	COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	Q86TI0	TBC1D1	P31749	AKT1	S629	T632A	632	Missense	distal	3	no	11.727	11.670	EPSD	COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	Q86TI0	TBC1D1	P31749	AKT1	S629	R624G	624	Missense	distal	-5	no	11.727	7.663	EPSD	COSMIC	7.780	Loss
AGC_Akt_AKT1_ST	Q86TI0	TBC1D1	P31749	AKT1	T671	A670T	670	Missense	proximal	-1	no	10.768	10.795	EPSD	COSMIC	7.780	Up-regulation
AGC_Akt_AKT1_ST	Q86TI0	TBC1D1	P31749	AKT1	T671	V669I	669	Missense	proximal	-2	no	10.768	10.717	EPSD	COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	Q86TI0	TBC1D1	P31749	AKT1	T716	R718H	718	Missense	proximal	2	no	8.197	7.836	EPSD	COSMIC;GDSC	7.780	Down-regulation
AGC_Akt_AKT1_ST	Q86TI0	TBC1D1	P31749	AKT1	S717	R718H	718	Missense	proximal	1	no	8.913	8.590	EPSD	COSMIC;GDSC	7.780	Down-regulation
AGC_Akt_AKT1_ST	Q86TI0	TBC1D1	P31749	AKT1	S1150	R1148W	1148	Missense	proximal	-2	no	11.421	10.167	EPSD	COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	Q86TI0	TBC1D1	P31749	AKT1	S1154	R1148W	1148	Missense	distal	-6	no	11.797	11.649	EPSD	COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	Q9Y2I7	PIKFYVE	P31749	AKT1	T22	H26R	26	Missense	distal	4	no	10.847	10.662	EPSD	COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	Q9Y2I7	PIKFYVE	P31749	AKT1	S85	Q78L	78	Missense	distal	-7	no	12.329	12.234	EPSD	COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	Q9Y2I7	PIKFYVE	P31749	AKT1	S85	V86A	86	Missense	proximal	1	no	12.329	12.257	EPSD	COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	Q9Y2I7	PIKFYVE	P31749	AKT1	T90	V86A	86	Missense	distal	-4	no	9.944	10.316	EPSD	COSMIC	7.780	Up-regulation
AGC_Akt_AKT1_ST	Q9Y2I7	PIKFYVE	P31749	AKT1	S105	R110G	110	Missense	distal	5	no	10.955	10.884	EPSD	COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	Q9Y2I7	PIKFYVE	P31749	AKT1	S105	R111Q	111	Missense	distal	6	no	10.955	10.884	EPSD	COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	Q9Y2I7	PIKFYVE	P31749	AKT1	S132	L138I	138	Missense	distal	6	no	11.907	11.846	EPSD	COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	Q9Y2I7	PIKFYVE	P31749	AKT1	S132	Q127P	127	Missense	distal	-5	no	11.907	12.125	EPSD	COSMIC	7.780	Up-regulation
AGC_Akt_AKT1_ST	Q9Y2I7	PIKFYVE	P31749	AKT1	S219	S219L	219	Missense	central	0	yes	9.673	0.000	EPSD	COSMIC	7.780	Loss
AGC_Akt_AKT1_ST	Q9Y2I7	PIKFYVE	P31749	AKT1	S291	G297E	297	Missense	distal	6	no	11.762	11.808	EPSD	COSMIC	7.780	Up-regulation
AGC_Akt_AKT1_ST	Q9Y2I7	PIKFYVE	P31749	AKT1	S318	P319S	319	Missense	proximal	1	no	11.141	11.296	PhosphoSitePlus;EPSD	COSMIC	7.780	Up-regulation
AGC_Akt_AKT1_ST	Q9Y2I7	PIKFYVE	P31749	AKT1	T341	R334G	334	Missense	distal	-7	no	9.937	9.695	EPSD	COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	Q9Y2I7	PIKFYVE	P31749	AKT1	S499	P494L	494	Missense	distal	-5	no	9.990	9.874	EPSD	COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	Q9Y2I7	PIKFYVE	P31749	AKT1	S501	P494L	494	Missense	distal	-7	no	8.102	8.062	EPSD	COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	Q9Y2I7	PIKFYVE	P31749	AKT1	S845	T838I	838	Missense	distal	-7	no	13.120	12.698	EPSD	COSMIC;CCLE	7.780	Down-regulation
AGC_Akt_AKT1_ST	Q9Y2I7	PIKFYVE	P31749	AKT1	S845	T838A	838	Missense	distal	-7	no	13.120	12.920	EPSD	COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	Q9Y2I7	PIKFYVE	P31749	AKT1	S1474	S1475F	1475	Missense	proximal	1	no	12.258	12.276	EPSD	COSMIC	7.780	Up-regulation
AGC_Akt_AKT1_ST	Q9Y2I7	PIKFYVE	P31749	AKT1	S1474	R1471K	1471	Missense	distal	-3	no	12.258	7.738	EPSD	COSMIC	7.780	Loss
AGC_Akt_AKT1_ST	Q9Y2I7	PIKFYVE	P31749	AKT1	S1496	A1492T	1492	Missense	distal	-4	no	7.543	8.320	EPSD	COSMIC	7.780	Gain
AGC_Akt_AKT1_ST	Q9Y2I7	PIKFYVE	P31749	AKT1	S1522	P1527L	1527	Missense	distal	5	no	8.574	8.561	EPSD	COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	Q9Y2I7	PIKFYVE	P31749	AKT1	S1522	S1526C	1526	Missense	distal	4	no	8.574	8.919	EPSD	COSMIC	7.780	Up-regulation
AGC_Akt_AKT1_ST	Q9Y2I7	PIKFYVE	P31749	AKT1	S1522	K1516M	1516	Missense	distal	-6	no	8.574	8.492	EPSD	COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	Q9Y2I7	PIKFYVE	P31749	AKT1	S1522	P1521H	1521	Missense	proximal	-1	no	8.574	8.569	EPSD	COSMIC;GDSC;CCLE	7.780	Down-regulation
AGC_Akt_AKT1_ST	Q9Y2I7	PIKFYVE	P31749	AKT1	S1522	G1528R	1528	Missense	distal	6	no	8.574	8.678	EPSD	COSMIC	7.780	Up-regulation
AGC_Akt_AKT1_ST	Q9Y2I7	PIKFYVE	P31749	AKT1	T2026	V2032F	2032	Missense	distal	6	no	10.327	10.321	EPSD	COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	Q9Y4P1	ATG4B	P31749	AKT1	S34	R31I	31	Missense	distal	-3	no	11.739	4.658	PhosphoSitePlus	COSMIC	7.780	Loss
AGC_Akt_AKT1_ST	Q9Y4P1	ATG4B	P31749	AKT1	S34	E41K	41	Missense	distal	7	no	11.739	11.773	PhosphoSitePlus	COSMIC	7.780	Up-regulation
AGC_Akt_AKT1_ST	Q9Y4P1	ATG4B	P31749	AKT1	S383	E378G	378	Missense	distal	-5	no	8.846	8.876	EPSD	COSMIC	7.780	Up-regulation
AGC_Akt_AKT1_ST	Q6R327	RICTOR	P31749	AKT1	S21	E23D	23	Missense	proximal	2	no	15.434	15.024	EPSD	COSMIC;GDSC;CCLE	7.780	Down-regulation
AGC_Akt_AKT1_ST	Q6R327	RICTOR	P31749	AKT1	S21	P27S	27	Missense	distal	6	no	15.434	15.528	EPSD	COSMIC	7.780	Up-regulation
AGC_Akt_AKT1_ST	Q6R327	RICTOR	P31749	AKT1	S21	R14Q	14	Missense	distal	-7	no	15.434	15.240	EPSD	COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	Q6R327	RICTOR	P31749	AKT1	S21	G17E	17	Missense	distal	-4	no	15.434	15.651	EPSD	COSMIC	7.780	Up-regulation
AGC_Akt_AKT1_ST	Q6R327	RICTOR	P31749	AKT1	S35	E40D	40	Missense	distal	5	no	10.036	9.994	EPSD	COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	Q6R327	RICTOR	P31749	AKT1	S35	D29E	29	Missense	distal	-6	no	10.036	10.108	EPSD	COSMIC	7.780	Up-regulation
AGC_Akt_AKT1_ST	Q6R327	RICTOR	P31749	AKT1	S383	P378L	378	Missense	distal	-5	no	13.047	12.931	EPSD	COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	Q6R327	RICTOR	P31749	AKT1	S383	R384G	384	Missense	proximal	1	no	13.047	12.597	EPSD	COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	Q6R327	RICTOR	P31749	AKT1	S383	R380L	380	Missense	distal	-3	no	13.047	6.053	EPSD	COSMIC	7.780	Loss
AGC_Akt_AKT1_ST	Q6R327	RICTOR	P31749	AKT1	S383	L377I	377	Missense	distal	-6	no	13.047	12.977	EPSD	COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	Q6R327	RICTOR	P31749	AKT1	S383	H379Y	379	Missense	distal	-4	no	13.047	13.160	EPSD	COSMIC	7.780	Up-regulation
AGC_Akt_AKT1_ST	Q6R327	RICTOR	P31749	AKT1	S810	S816F	816	Missense	distal	6	no	9.152	9.032	EPSD	COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	Q6R327	RICTOR	P31749	AKT1	S810	L804V	804	Missense	distal	-6	no	9.152	9.127	EPSD	COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	Q6R327	RICTOR	P31749	AKT1	S1035	P1041S	1041	Missense	distal	6	no	11.352	11.446	EPSD	COSMIC;GDSC;CCLE	7.780	Up-regulation
AGC_Akt_AKT1_ST	Q6R327	RICTOR	P31749	AKT1	S1035	T1029A	1029	Missense	distal	-6	no	11.352	11.266	EPSD	COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	Q6R327	RICTOR	P31749	AKT1	S1037	P1041S	1041	Missense	distal	4	no	9.015	8.859	EPSD	COSMIC;GDSC;CCLE	7.780	Down-regulation
AGC_Akt_AKT1_ST	Q6R327	RICTOR	P31749	AKT1	T1133	D1140E	1140	Missense	distal	7	no	10.556	10.599	EPSD	COSMIC	7.780	Up-regulation
AGC_Akt_AKT1_ST	Q6R327	RICTOR	P31749	AKT1	T1133	T1135A	1135	Missense	proximal	2	no	10.556	10.255	EPSD	COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	Q6R327	RICTOR	P31749	AKT1	T1133	D1140Y	1140	Missense	distal	7	no	10.556	10.590	EPSD	COSMIC	7.780	Up-regulation
AGC_Akt_AKT1_ST	Q6R327	RICTOR	P31749	AKT1	T1135	D1140E	1140	Missense	distal	5	no	13.824	13.866	PhosphoSitePlus	COSMIC	7.780	Up-regulation
AGC_Akt_AKT1_ST	Q6R327	RICTOR	P31749	AKT1	T1135	T1135A	1135	Missense	central	0	yes	13.824	0.000	PhosphoSitePlus	COSMIC	7.780	Loss
AGC_Akt_AKT1_ST	Q6R327	RICTOR	P31749	AKT1	T1135	D1140Y	1140	Missense	distal	5	no	13.824	13.856	PhosphoSitePlus	COSMIC	7.780	Up-regulation
AGC_Akt_AKT1_ST	Q6R327	RICTOR	P31749	AKT1	T1198	T1198A	1198	Missense	central	0	yes	8.944	0.000	EPSD	COSMIC	7.780	Loss
AGC_Akt_AKT1_ST	Q6R327	RICTOR	P31749	AKT1	S1219	K1214Q	1214	Missense	distal	-5	no	11.267	9.436	EPSD	COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	Q6R327	RICTOR	P31749	AKT1	S1219	M1213L	1213	Missense	distal	-6	no	11.267	11.278	EPSD	COSMIC	7.780	Up-regulation
AGC_Akt_AKT1_ST	Q6R327	RICTOR	P31749	AKT1	S1219	Q1218P	1218	Missense	proximal	-1	no	11.267	11.259	EPSD	COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	Q6R327	RICTOR	P31749	AKT1	S1302	A1309V	1309	Missense	distal	7	no	13.316	13.312	EPSD	COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	Q6R327	RICTOR	P31749	AKT1	S1302	P1297S	1297	Missense	distal	-5	no	13.316	12.856	EPSD	COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	Q6R327	RICTOR	P31749	AKT1	S1302	R1299K	1299	Missense	distal	-3	no	13.316	8.796	EPSD	COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	Q6R327	RICTOR	P31749	AKT1	S1408	R1410W	1410	Missense	proximal	2	no	14.254	13.799	EPSD	COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	Q6R327	RICTOR	P31749	AKT1	S1408	S1406F	1406	Missense	proximal	-2	no	14.254	13.387	EPSD	COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	Q6R327	RICTOR	P31749	AKT1	S1408	T1402P	1402	Missense	distal	-6	no	14.254	14.159	EPSD	COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	Q6R327	RICTOR	P31749	AKT1	S1408	R1410Q	1410	Missense	proximal	2	no	14.254	14.137	EPSD	COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	Q6R327	RICTOR	P31749	AKT1	S1415	R1410W	1410	Missense	distal	-5	no	8.908	3.388	EPSD	COSMIC	7.780	Loss
AGC_Akt_AKT1_ST	Q6R327	RICTOR	P31749	AKT1	S1415	G1420S	1420	Missense	distal	5	no	8.908	8.971	EPSD	COSMIC	7.780	Up-regulation
AGC_Akt_AKT1_ST	Q6R327	RICTOR	P31749	AKT1	S1415	S1421L	1421	Missense	distal	6	no	8.908	8.804	EPSD	COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	Q6R327	RICTOR	P31749	AKT1	S1415	R1410Q	1410	Missense	distal	-5	no	8.908	4.680	EPSD	COSMIC	7.780	Loss
AGC_Akt_AKT1_ST	Q9Y261	FOXA2	P31749	AKT1	T156	P160L	160	Missense	distal	4	no	11.910	11.942	PhosphoSitePlus	COSMIC	7.780	Up-regulation
AGC_Akt_AKT1_ST	Q9Y261	FOXA2	P31749	AKT1	T156	A158S	158	Missense	proximal	2	no	11.910	12.285	PhosphoSitePlus	COSMIC	7.780	Up-regulation
AGC_Akt_AKT1_ST	Q9Y261	FOXA2	P31749	AKT1	T156	S154R	154	Missense	proximal	-2	no	11.910	11.721	PhosphoSitePlus	COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	Q9Y261	FOXA2	P31749	AKT1	T156	Y162C	162	Missense	distal	6	no	11.910	11.795	PhosphoSitePlus	COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	Q9Y261	FOXA2	P31749	AKT1	T156	R153C	153	Missense	distal	-3	no	11.910	5.736	PhosphoSitePlus	COSMIC	7.780	Loss
AGC_Akt_AKT1_ST	Q9Y261	FOXA2	P31749	AKT1	T156	S163L	163	Missense	distal	7	no	11.910	11.843	PhosphoSitePlus	COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	Q9Y261	FOXA2	P31749	AKT1	T156	A158T	158	Missense	proximal	2	no	11.910	12.211	PhosphoSitePlus	COSMIC	7.780	Up-regulation
AGC_Akt_AKT1_ST	Q9Y261	FOXA2	P31749	AKT1	T156	H157Q	157	Missense	proximal	1	no	11.910	11.937	PhosphoSitePlus	COSMIC	7.780	Up-regulation
AGC_Akt_AKT1_ST	Q9Y261	FOXA2	P31749	AKT1	T156	Y155C	155	Missense	proximal	-1	no	11.910	11.875	PhosphoSitePlus	COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	Q9Y261	FOXA2	P31749	AKT1	S212	R208H	208	Missense	distal	-4	no	8.020	6.961	EPSD	COSMIC	7.780	Loss
AGC_Akt_AKT1_ST	Q9Y261	FOXA2	P31749	AKT1	S212	I207L	207	Missense	distal	-5	no	8.020	8.461	EPSD	COSMIC	7.780	Up-regulation
AGC_Akt_AKT1_ST	Q9Y261	FOXA2	P31749	AKT1	S212	H209Y	209	Missense	distal	-3	no	8.020	5.129	EPSD	COSMIC	7.780	Loss
AGC_Akt_AKT1_ST	Q9Y261	FOXA2	P31749	AKT1	S212	R208C	208	Missense	distal	-4	no	8.020	6.341	EPSD	COSMIC	7.780	Loss
AGC_Akt_AKT1_ST	Q9Y261	FOXA2	P31749	AKT1	S212	F217S	217	Missense	distal	5	no	8.020	8.092	EPSD	COSMIC	7.780	Up-regulation
AGC_Akt_AKT1_ST	Q9Y261	FOXA2	P31749	AKT1	S212	L211F	211	Missense	proximal	-1	no	8.020	8.014	EPSD	COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	Q9Y261	FOXA2	P31749	AKT1	S212	I207M	207	Missense	distal	-5	no	8.020	8.065	EPSD	COSMIC	7.780	Up-regulation
AGC_Akt_AKT1_ST	Q9Y261	FOXA2	P31749	AKT1	S212	L218R	218	Missense	distal	6	no	8.020	8.122	EPSD	COSMIC	7.780	Up-regulation
AGC_Akt_AKT1_ST	Q9Y261	FOXA2	P31749	AKT1	S212	F217L	217	Missense	distal	5	no	8.020	8.026	EPSD	COSMIC	7.780	Up-regulation
AGC_Akt_AKT1_ST	Q9Y261	FOXA2	P31749	AKT1	S212	S212F	212	Missense	central	0	yes	8.020	0.000	EPSD	COSMIC	7.780	Loss
AGC_Akt_AKT1_ST	Q9Y261	FOXA2	P31749	AKT1	S212	F217Y	217	Missense	distal	5	no	8.020	8.049	EPSD	COSMIC	7.780	Up-regulation
AGC_Akt_AKT1_ST	Q9Y261	FOXA2	P31749	AKT1	S212	S206F	206	Missense	distal	-6	no	8.020	7.945	EPSD	COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	Q9Y261	FOXA2	P31749	AKT1	S212	D215Y	215	Missense	distal	3	no	8.020	8.063	EPSD	COSMIC	7.780	Up-regulation
AGC_Akt_AKT1_ST	Q9Y261	FOXA2	P31749	AKT1	S212	I207T	207	Missense	distal	-5	no	8.020	8.857	EPSD	COSMIC	7.780	Up-regulation
AGC_Akt_AKT1_ST	P45985	MAP2K4	P31749	AKT1	T78	E74K	74	Missense	distal	-4	no	10.970	11.554	EPSD	COSMIC	7.780	Up-regulation
AGC_Akt_AKT1_ST	P45985	MAP2K4	P31749	AKT1	T78	P71S	71	Missense	distal	-7	no	10.970	11.164	EPSD	COSMIC	7.780	Up-regulation
AGC_Akt_AKT1_ST	P45985	MAP2K4	P31749	AKT1	T78	R77G	77	Missense	proximal	-1	no	10.970	10.930	EPSD	COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	P45985	MAP2K4	P31749	AKT1	T78	G85R	85	Missense	distal	7	no	10.970	11.051	EPSD	COSMIC	7.780	Up-regulation
AGC_Akt_AKT1_ST	P45985	MAP2K4	P31749	AKT1	S80	E74K	74	Missense	distal	-6	no	16.956	17.023	PhosphoSitePlus	COSMIC	7.780	Up-regulation
AGC_Akt_AKT1_ST	P45985	MAP2K4	P31749	AKT1	S80	R77G	77	Missense	distal	-3	no	16.956	10.200	PhosphoSitePlus	COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	P45985	MAP2K4	P31749	AKT1	S80	G85R	85	Missense	distal	5	no	16.956	17.026	PhosphoSitePlus	COSMIC	7.780	Up-regulation
AGC_Akt_AKT1_ST	P45985	MAP2K4	P31749	AKT1	S90	G85R	85	Missense	distal	-5	no	6.710	10.774	EPSD	COSMIC	7.780	Gain
AGC_Akt_AKT1_ST	P45985	MAP2K4	P31749	AKT1	S251	C246R	246	Missense	distal	-5	no	5.348	9.425	EPSD	COSMIC	7.780	Gain
AGC_Akt_AKT1_ST	P45985	MAP2K4	P31749	AKT1	S257	L254R	254	Missense	distal	-3	no	2.963	9.956	EPSD	COSMIC;GDSC;CCLE	7.780	Gain
AGC_Akt_AKT1_ST	P45985	MAP2K4	P31749	AKT1	S288	G283R	283	Missense	distal	-5	no	4.387	8.452	EPSD	COSMIC	7.780	Gain
AGC_Akt_AKT1_ST	P45985	MAP2K4	P31749	AKT1	S292	G294R	294	Missense	proximal	2	no	9.191	9.352	EPSD	COSMIC	7.780	Up-regulation
AGC_Akt_AKT1_ST	P45985	MAP2K4	P31749	AKT1	S292	S292N	292	Missense	central	0	yes	9.191	0.000	EPSD	COSMIC	7.780	Loss
AGC_Akt_AKT1_ST	P45985	MAP2K4	P31749	AKT1	S292	D289G	289	Missense	distal	-3	no	9.191	8.386	EPSD	COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	P45985	MAP2K4	P31749	AKT1	S292	S288F	288	Missense	distal	-4	no	9.191	8.024	EPSD	COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	P45985	MAP2K4	P31749	AKT1	S292	D289Y	289	Missense	distal	-3	no	9.191	7.553	EPSD	COSMIC	7.780	Loss
AGC_Akt_AKT1_ST	P45985	MAP2K4	P31749	AKT1	S292	E299D	299	Missense	distal	7	no	9.191	9.148	EPSD	COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	P45985	MAP2K4	P31749	AKT1	S292	V290F	290	Missense	proximal	-2	no	9.191	9.515	EPSD	COSMIC	7.780	Up-regulation
AGC_Akt_AKT1_ST	P45985	MAP2K4	P31749	AKT1	S292	S292R	292	Missense	central	0	yes	9.191	0.000	EPSD	COSMIC	7.780	Loss
AGC_Akt_AKT1_ST	P45985	MAP2K4	P31749	AKT1	S292	I295F	295	Missense	distal	3	no	9.191	9.224	EPSD	COSMIC	7.780	Up-regulation
AGC_Akt_AKT1_ST	P45985	MAP2K4	P31749	AKT1	S292	S288P	288	Missense	distal	-4	no	9.191	8.455	EPSD	COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	P45985	MAP2K4	P31749	AKT1	S292	S288C	288	Missense	distal	-4	no	9.191	7.598	EPSD	COSMIC	7.780	Loss
AGC_Akt_AKT1_ST	P45985	MAP2K4	P31749	AKT1	S292	G294V	294	Missense	proximal	2	no	9.191	8.985	EPSD	COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	P45985	MAP2K4	P31749	AKT1	S292	D289V	289	Missense	distal	-3	no	9.191	8.277	EPSD	COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	P45985	MAP2K4	P31749	AKT1	S292	D289N	289	Missense	distal	-3	no	9.191	7.665	EPSD	COSMIC	7.780	Loss
AGC_Akt_AKT1_ST	P45985	MAP2K4	P31749	AKT1	S292	E299V	299	Missense	distal	7	no	9.191	9.170	EPSD	COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	P45985	MAP2K4	P31749	AKT1	S292	D285N	285	Missense	distal	-7	no	9.191	9.449	EPSD	COSMIC	7.780	Up-regulation
AGC_Akt_AKT1_ST	P45985	MAP2K4	P31749	AKT1	S292	W291R	291	Missense	proximal	-1	no	9.191	9.252	EPSD	COSMIC	7.780	Up-regulation
AGC_Akt_AKT1_ST	P45985	MAP2K4	P31749	AKT1	S292	I295M	295	Missense	distal	3	no	9.191	9.237	EPSD	COSMIC	7.780	Up-regulation
AGC_Akt_AKT1_ST	P45985	MAP2K4	P31749	AKT1	S292	L297F	297	Missense	distal	5	no	9.191	9.185	EPSD	COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	P45985	MAP2K4	P31749	AKT1	S292	T296R	296	Missense	distal	4	no	9.191	9.207	EPSD	COSMIC	7.780	Up-regulation
AGC_Akt_AKT1_ST	P45985	MAP2K4	P31749	AKT1	T296	W291R	291	Missense	distal	-5	no	2.670	8.190	EPSD	COSMIC	7.780	Gain
AGC_Akt_AKT1_ST	Q96CG3	TIFA	P31749	AKT1	T9	T14I	14	Missense	distal	5	no	8.390	8.293	PhosphoSitePlus	COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	Q96CG3	TIFA	P31749	AKT1	S174	E178Q	178	Missense	distal	4	no	8.143	8.198	EPSD	COSMIC	7.780	Up-regulation
AGC_Akt_AKT1_ST	Q96CG3	TIFA	P31749	AKT1	S174	S171F	171	Missense	distal	-3	no	8.143	10.325	EPSD	COSMIC	7.780	Up-regulation
AGC_Akt_AKT1_ST	Q96CG3	TIFA	P31749	AKT1	S175	E178Q	178	Missense	distal	3	no	7.812	7.781	EPSD	COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	Q96CG3	TIFA	P31749	AKT1	S175	S171F	171	Missense	distal	-4	no	7.812	6.644	EPSD	COSMIC	7.780	Loss
AGC_Akt_AKT1_ST	Q8WX93	PALLD	P31749	AKT1	S13	D16Y	16	Missense	distal	3	no	8.762	8.805	EPSD	COSMIC	7.780	Up-regulation
AGC_Akt_AKT1_ST	Q8WX93	PALLD	P31749	AKT1	S13	F10L	10	Missense	distal	-3	no	8.762	7.363	EPSD	COSMIC;CCLE	7.780	Loss
AGC_Akt_AKT1_ST	Q8WX93	PALLD	P31749	AKT1	S192	G195E	195	Missense	distal	3	no	12.748	12.798	EPSD	COSMIC	7.780	Up-regulation
AGC_Akt_AKT1_ST	Q8WX93	PALLD	P31749	AKT1	S192	K187R	187	Missense	distal	-5	no	12.748	15.145	EPSD	COSMIC	7.780	Up-regulation
AGC_Akt_AKT1_ST	Q8WX93	PALLD	P31749	AKT1	S356	I361V	361	Missense	distal	5	no	7.847	7.884	EPSD	COSMIC	7.780	Up-regulation
AGC_Akt_AKT1_ST	Q8WX93	PALLD	P31749	AKT1	S356	G351V	351	Missense	distal	-5	no	7.847	7.597	EPSD	COSMIC	7.780	Loss
AGC_Akt_AKT1_ST	Q8WX93	PALLD	P31749	AKT1	S356	S356F	356	Missense	central	0	yes	7.847	0.000	EPSD	COSMIC	7.780	Loss
AGC_Akt_AKT1_ST	Q8WX93	PALLD	P31749	AKT1	S356	D353Y	353	Missense	distal	-3	no	7.847	6.208	EPSD	COSMIC	7.780	Loss
AGC_Akt_AKT1_ST	Q8WX93	PALLD	P31749	AKT1	S356	G351S	351	Missense	distal	-5	no	7.847	7.441	EPSD	COSMIC	7.780	Loss
AGC_Akt_AKT1_ST	Q8WX93	PALLD	P31749	AKT1	S356	S356Y	356	Missense	central	0	yes	7.847	0.000	EPSD	COSMIC	7.780	Loss
AGC_Akt_AKT1_ST	Q8WX93	PALLD	P31749	AKT1	S392	Q387K	387	Missense	distal	-5	no	7.153	8.984	EPSD	COSMIC	7.780	Gain
AGC_Akt_AKT1_ST	Q8WX93	PALLD	P31749	AKT1	S394	Q387K	387	Missense	distal	-7	no	8.071	8.252	EPSD	COSMIC	7.780	Up-regulation
AGC_Akt_AKT1_ST	Q8WX93	PALLD	P31749	AKT1	S394	T391I	391	Missense	distal	-3	no	8.071	8.012	EPSD	COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	Q8WX93	PALLD	P31749	AKT1	S394	S399L	399	Missense	distal	5	no	8.071	8.005	EPSD	COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	Q8WX93	PALLD	P31749	AKT1	S479	G478R	478	Missense	proximal	-1	no	8.089	8.129	EPSD	COSMIC	7.780	Up-regulation
AGC_Akt_AKT1_ST	Q8WX93	PALLD	P31749	AKT1	S479	R476G	476	Missense	distal	-3	no	8.089	1.333	EPSD	COSMIC	7.780	Loss
AGC_Akt_AKT1_ST	Q8WX93	PALLD	P31749	AKT1	S479	G478V	478	Missense	proximal	-1	no	8.089	8.084	EPSD	COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	Q8WX93	PALLD	P31749	AKT1	S479	G478W	478	Missense	proximal	-1	no	8.089	8.068	EPSD	COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	Q7Z6J0	SH3RF1	P31749	AKT1	S58	G57A	57	Missense	proximal	-1	no	8.450	8.459	EPSD	COSMIC	7.780	Up-regulation
AGC_Akt_AKT1_ST	Q7Z6J0	SH3RF1	P31749	AKT1	S125	G118V	118	Missense	distal	-7	no	10.727	10.635	EPSD	COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	Q7Z6J0	SH3RF1	P31749	AKT1	S125	G118R	118	Missense	distal	-7	no	10.727	10.969	EPSD	COSMIC	7.780	Up-regulation
AGC_Akt_AKT1_ST	Q7Z6J0	SH3RF1	P31749	AKT1	S304	K300N	300	Missense	distal	-4	no	10.102	9.463	PhosphoSitePlus	COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	Q7Z6J0	SH3RF1	P31749	AKT1	T306	K300N	300	Missense	distal	-6	no	8.492	8.425	EPSD	COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	Q7Z6J0	SH3RF1	P31749	AKT1	T509	P503S	503	Missense	distal	-6	no	10.462	10.526	EPSD	COSMIC	7.780	Up-regulation
AGC_Akt_AKT1_ST	Q7Z6J0	SH3RF1	P31749	AKT1	T529	P533L	533	Missense	distal	4	no	11.455	11.487	EPSD	COSMIC	7.780	Up-regulation
AGC_Akt_AKT1_ST	Q7Z6J0	SH3RF1	P31749	AKT1	T529	R526W	526	Missense	distal	-3	no	11.455	2.514	EPSD	COSMIC	7.780	Loss
AGC_Akt_AKT1_ST	Q7Z6J0	SH3RF1	P31749	AKT1	T684	P678L	678	Missense	distal	-6	no	9.469	9.483	EPSD	COSMIC	7.780	Up-regulation
AGC_Akt_AKT1_ST	Q7Z6J0	SH3RF1	P31749	AKT1	T684	L686F	686	Missense	proximal	2	no	9.469	9.438	EPSD	COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	Q7Z6J0	SH3RF1	P31749	AKT1	S735	R730Q	730	Missense	distal	-5	no	10.577	6.349	EPSD	COSMIC	7.780	Loss
AGC_Akt_AKT1_ST	Q7Z6J0	SH3RF1	P31749	AKT1	S735	S735F	735	Missense	central	0	yes	10.577	0.000	EPSD	COSMIC	7.780	Loss
AGC_Akt_AKT1_ST	Q7Z6J0	SH3RF1	P31749	AKT1	S800	P807L	807	Missense	distal	7	no	12.055	12.047	EPSD	COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	Q7Z6J0	SH3RF1	P31749	AKT1	S818	S818F	818	Missense	central	0	yes	8.748	0.000	EPSD	COSMIC	7.780	Loss
AGC_Akt_AKT1_ST	Q8NCD3	HJURP	P31749	AKT1	S201	R199G	199	Missense	proximal	-2	no	8.190	7.684	EPSD	COSMIC	7.780	Loss
AGC_Akt_AKT1_ST	Q8NCD3	HJURP	P31749	AKT1	S201	A206V	206	Missense	distal	5	no	8.190	8.181	EPSD	COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	Q8NCD3	HJURP	P31749	AKT1	S201	R196C	196	Missense	distal	-5	no	8.190	4.113	EPSD	COSMIC	7.780	Loss
AGC_Akt_AKT1_ST	Q8NCD3	HJURP	P31749	AKT1	S276	P279L	279	Missense	distal	3	no	11.646	11.630	EPSD	COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	Q8NCD3	HJURP	P31749	AKT1	S276	L275I	275	Missense	proximal	-1	no	11.646	11.625	EPSD	COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	Q8NCD3	HJURP	P31749	AKT1	S276	H269L	269	Missense	distal	-7	no	11.646	11.658	EPSD	COSMIC;GDSC;CCLE	7.780	Up-regulation
AGC_Akt_AKT1_ST	Q8NCD3	HJURP	P31749	AKT1	T380	R377C	377	Missense	distal	-3	no	12.598	6.425	EPSD	COSMIC	7.780	Loss
AGC_Akt_AKT1_ST	Q8NCD3	HJURP	P31749	AKT1	T380	R377H	377	Missense	distal	-3	no	12.598	7.900	EPSD	COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	Q8NCD3	HJURP	P31749	AKT1	T380	K375N	375	Missense	distal	-5	no	12.598	10.511	EPSD	COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	Q8NCD3	HJURP	P31749	AKT1	S382	R377C	377	Missense	distal	-5	no	10.087	6.010	EPSD	COSMIC	7.780	Loss
AGC_Akt_AKT1_ST	Q8NCD3	HJURP	P31749	AKT1	S382	R377H	377	Missense	distal	-5	no	10.087	6.992	EPSD	COSMIC	7.780	Loss
AGC_Akt_AKT1_ST	Q8NCD3	HJURP	P31749	AKT1	S382	K375N	375	Missense	distal	-7	no	10.087	9.930	EPSD	COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	Q8NCD3	HJURP	P31749	AKT1	S448	E444K	444	Missense	distal	-4	no	7.773	8.357	EPSD	COSMIC	7.780	Gain
AGC_Akt_AKT1_ST	Q8NCD3	HJURP	P31749	AKT1	S486	G479D	479	Missense	distal	-7	no	13.501	13.315	PhosphoSitePlus	COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	Q8NCD3	HJURP	P31749	AKT1	S486	T482I	482	Missense	distal	-4	no	13.501	12.063	PhosphoSitePlus	COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	Q8NCD3	HJURP	P31749	AKT1	S486	K493N	493	Missense	distal	7	no	13.501	13.465	PhosphoSitePlus	COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	Q8NCD3	HJURP	P31749	AKT1	S486	A492E	492	Missense	distal	6	no	13.501	13.524	PhosphoSitePlus	COSMIC	7.780	Up-regulation
AGC_Akt_AKT1_ST	Q8NCD3	HJURP	P31749	AKT1	S489	T482I	482	Missense	distal	-7	no	8.222	7.800	EPSD	COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	Q8NCD3	HJURP	P31749	AKT1	S489	K493N	493	Missense	distal	4	no	8.222	8.354	EPSD	COSMIC	7.780	Up-regulation
AGC_Akt_AKT1_ST	Q8NCD3	HJURP	P31749	AKT1	S489	A492E	492	Missense	distal	3	no	8.222	8.239	EPSD	COSMIC	7.780	Up-regulation
AGC_Akt_AKT1_ST	Q8NCD3	HJURP	P31749	AKT1	S496	K493N	493	Missense	distal	-3	no	8.578	5.621	EPSD	COSMIC	7.780	Loss
AGC_Akt_AKT1_ST	Q8NCD3	HJURP	P31749	AKT1	S496	A492E	492	Missense	distal	-4	no	8.578	8.788	EPSD	COSMIC	7.780	Up-regulation
AGC_Akt_AKT1_ST	Q8NCD3	HJURP	P31749	AKT1	S498	K493N	493	Missense	distal	-5	no	10.479	8.391	EPSD	COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	Q8NCD3	HJURP	P31749	AKT1	S498	A492E	492	Missense	distal	-6	no	10.479	10.487	EPSD	COSMIC	7.780	Up-regulation
AGC_Akt_AKT1_ST	Q8NCD3	HJURP	P31749	AKT1	S555	G550R	550	Missense	distal	-5	no	6.436	10.500	EPSD	COSMIC	7.780	Gain
AGC_Akt_AKT1_ST	Q8NCD3	HJURP	P31749	AKT1	S557	G550R	550	Missense	distal	-7	no	9.611	9.853	EPSD	COSMIC	7.780	Up-regulation
AGC_Akt_AKT1_ST	Q8NCD3	HJURP	P31749	AKT1	S736	R731K	731	Missense	distal	-5	no	11.394	8.996	EPSD	COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	P35568	IRS1	P31749	AKT1	S36	G40V	40	Missense	distal	4	no	9.585	9.591	EPSD	COSMIC	7.780	Up-regulation
AGC_Akt_AKT1_ST	P35568	IRS1	P31749	AKT1	S36	G39R	39	Missense	distal	3	no	9.585	9.659	EPSD	COSMIC	7.780	Up-regulation
AGC_Akt_AKT1_ST	P35568	IRS1	P31749	AKT1	S36	A34S	34	Missense	proximal	-2	no	9.585	10.037	EPSD	COSMIC	7.780	Up-regulation
AGC_Akt_AKT1_ST	P35568	IRS1	P31749	AKT1	S36	V31I	31	Missense	distal	-5	no	9.585	9.332	EPSD	COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	P35568	IRS1	P31749	AKT1	S189	R184C	184	Missense	distal	-5	no	9.152	5.075	EPSD	COSMIC	7.780	Loss
AGC_Akt_AKT1_ST	P35568	IRS1	P31749	AKT1	S189	Y183C	183	Missense	distal	-6	no	9.152	9.065	EPSD	COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	P35568	IRS1	P31749	AKT1	S189	L185F	185	Missense	distal	-4	no	9.152	9.108	EPSD	COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	P35568	IRS1	P31749	AKT1	S189	K190N	190	Missense	proximal	1	no	9.152	8.996	EPSD	COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	P35568	IRS1	P31749	AKT1	S189	S189N	189	Missense	central	0	yes	9.152	0.000	EPSD	COSMIC	7.780	Loss
AGC_Akt_AKT1_ST	P35568	IRS1	P31749	AKT1	S193	K190N	190	Missense	distal	-3	no	9.594	6.638	EPSD	COSMIC	7.780	Loss
AGC_Akt_AKT1_ST	P35568	IRS1	P31749	AKT1	S193	S189N	189	Missense	distal	-4	no	9.594	9.027	EPSD	COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	P35568	IRS1	P31749	AKT1	S268	R265C	265	Missense	distal	-3	no	11.282	5.108	EPSD	COSMIC	7.780	Loss
AGC_Akt_AKT1_ST	P35568	IRS1	P31749	AKT1	S268	S274P	274	Missense	distal	6	no	11.282	11.188	EPSD	COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	P35568	IRS1	P31749	AKT1	S270	R265C	265	Missense	distal	-5	no	14.918	10.841	EPSD	COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	P35568	IRS1	P31749	AKT1	S270	S274P	274	Missense	distal	4	no	14.918	15.074	EPSD	COSMIC	7.780	Up-regulation
AGC_Akt_AKT1_ST	P35568	IRS1	P31749	AKT1	S272	R265C	265	Missense	distal	-7	no	12.914	12.435	EPSD	COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	P35568	IRS1	P31749	AKT1	S272	S274P	274	Missense	proximal	2	no	12.914	12.578	EPSD	COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	P35568	IRS1	P31749	AKT1	T305	R301C	301	Missense	distal	-4	no	13.125	11.447	EPSD	COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	P35568	IRS1	P31749	AKT1	T305	E306K	306	Missense	proximal	1	no	13.125	13.289	EPSD	COSMIC	7.780	Up-regulation
AGC_Akt_AKT1_ST	P35568	IRS1	P31749	AKT1	T305	A310T	310	Missense	distal	5	no	13.125	13.177	EPSD	COSMIC	7.780	Up-regulation
AGC_Akt_AKT1_ST	P35568	IRS1	P31749	AKT1	T305	R302L	302	Missense	distal	-3	no	13.125	6.131	EPSD	COSMIC	7.780	Loss
AGC_Akt_AKT1_ST	P35568	IRS1	P31749	AKT1	T305	I308M	308	Missense	distal	3	no	13.125	13.171	EPSD	COSMIC	7.780	Up-regulation
AGC_Akt_AKT1_ST	P35568	IRS1	P31749	AKT1	T305	A310V	310	Missense	distal	5	no	13.125	13.117	EPSD	COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	P35568	IRS1	P31749	AKT1	S307	R301C	301	Missense	distal	-6	no	16.317	16.136	EPSD	COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	P35568	IRS1	P31749	AKT1	S307	E306K	306	Missense	proximal	-1	no	16.317	16.338	EPSD	COSMIC	7.780	Up-regulation
AGC_Akt_AKT1_ST	P35568	IRS1	P31749	AKT1	S307	A310T	310	Missense	distal	3	no	16.317	16.374	EPSD	COSMIC	7.780	Up-regulation
AGC_Akt_AKT1_ST	P35568	IRS1	P31749	AKT1	S307	P313L	313	Missense	distal	6	no	16.317	16.307	EPSD	COSMIC;GDSC;CCLE	7.780	Down-regulation
AGC_Akt_AKT1_ST	P35568	IRS1	P31749	AKT1	S307	R302L	302	Missense	distal	-5	no	16.317	12.190	EPSD	COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	P35568	IRS1	P31749	AKT1	S307	I308M	308	Missense	proximal	1	no	16.317	16.502	EPSD	COSMIC	7.780	Up-regulation
AGC_Akt_AKT1_ST	P35568	IRS1	P31749	AKT1	S307	A310V	310	Missense	distal	3	no	16.317	16.285	EPSD	COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	P35568	IRS1	P31749	AKT1	T309	E306K	306	Missense	distal	-3	no	9.758	11.809	EPSD	COSMIC	7.780	Up-regulation
AGC_Akt_AKT1_ST	P35568	IRS1	P31749	AKT1	T309	A310T	310	Missense	proximal	1	no	9.758	10.025	EPSD	COSMIC	7.780	Up-regulation
AGC_Akt_AKT1_ST	P35568	IRS1	P31749	AKT1	T309	P313L	313	Missense	distal	4	no	9.758	9.791	EPSD	COSMIC;GDSC;CCLE	7.780	Up-regulation
AGC_Akt_AKT1_ST	P35568	IRS1	P31749	AKT1	T309	M316V	316	Missense	distal	7	no	9.758	9.762	EPSD	COSMIC	7.780	Up-regulation
AGC_Akt_AKT1_ST	P35568	IRS1	P31749	AKT1	T309	R302L	302	Missense	distal	-7	no	9.758	9.469	EPSD	COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	P35568	IRS1	P31749	AKT1	T309	M316I	316	Missense	distal	7	no	9.758	9.720	EPSD	COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	P35568	IRS1	P31749	AKT1	T309	I308M	308	Missense	proximal	-1	no	9.758	9.778	EPSD	COSMIC	7.780	Up-regulation
AGC_Akt_AKT1_ST	P35568	IRS1	P31749	AKT1	T309	A310V	310	Missense	proximal	1	no	9.758	9.831	EPSD	COSMIC	7.780	Up-regulation
AGC_Akt_AKT1_ST	P35568	IRS1	P31749	AKT1	S330	R327L	327	Missense	distal	-3	no	14.092	7.098	EPSD	COSMIC	7.780	Loss
AGC_Akt_AKT1_ST	P35568	IRS1	P31749	AKT1	S330	R325H	325	Missense	distal	-5	no	14.092	10.997	EPSD	COSMIC;CCLE	7.780	Down-regulation
AGC_Akt_AKT1_ST	P35568	IRS1	P31749	AKT1	S330	R327C	327	Missense	distal	-3	no	14.092	7.919	EPSD	COSMIC;CCLE	7.780	Down-regulation
AGC_Akt_AKT1_ST	P35568	IRS1	P31749	AKT1	S330	E333K	333	Missense	distal	3	no	14.092	14.136	EPSD	COSMIC	7.780	Up-regulation
AGC_Akt_AKT1_ST	P35568	IRS1	P31749	AKT1	S330	G332R	332	Missense	proximal	2	no	14.092	14.252	EPSD	COSMIC	7.780	Up-regulation
AGC_Akt_AKT1_ST	P35568	IRS1	P31749	AKT1	S330	R325C	325	Missense	distal	-5	no	14.092	10.015	EPSD	COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	P35568	IRS1	P31749	AKT1	S330	F324L	324	Missense	distal	-6	no	14.092	14.116	EPSD	COSMIC	7.780	Up-regulation
AGC_Akt_AKT1_ST	P35568	IRS1	P31749	AKT1	T335	G332R	332	Missense	distal	-3	no	2.657	9.413	EPSD	COSMIC	7.780	Gain
AGC_Akt_AKT1_ST	P35568	IRS1	P31749	AKT1	S337	G332R	332	Missense	distal	-5	no	5.009	9.073	EPSD	COSMIC	7.780	Gain
AGC_Akt_AKT1_ST	P35568	IRS1	P31749	AKT1	S341	S341L	341	Missense	central	0	yes	10.756	0.000	EPSD	COSMIC	7.780	Loss
AGC_Akt_AKT1_ST	P35568	IRS1	P31749	AKT1	S341	P346S	346	Missense	distal	5	no	10.756	10.809	EPSD	COSMIC	7.780	Up-regulation
AGC_Akt_AKT1_ST	P35568	IRS1	P31749	AKT1	S362	L369F	369	Missense	distal	7	no	8.382	8.375	EPSD	COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	P35568	IRS1	P31749	AKT1	S362	A356P	356	Missense	distal	-6	no	8.382	8.373	EPSD	COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	P35568	IRS1	P31749	AKT1	S362	R364Q	364	Missense	proximal	2	no	8.382	8.264	EPSD	COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	P35568	IRS1	P31749	AKT1	S362	R358Q	358	Missense	distal	-4	no	8.382	7.761	EPSD	COSMIC	7.780	Loss
AGC_Akt_AKT1_ST	P35568	IRS1	P31749	AKT1	S362	G361S	361	Missense	proximal	-1	no	8.382	8.411	EPSD	COSMIC	7.780	Up-regulation
AGC_Akt_AKT1_ST	P35568	IRS1	P31749	AKT1	S413	S415L	415	Missense	proximal	2	no	12.105	11.559	EPSD	COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	P35568	IRS1	P31749	AKT1	S413	G418V	418	Missense	distal	5	no	12.105	12.108	EPSD	COSMIC;GDSC;CCLE	7.780	Up-regulation
AGC_Akt_AKT1_ST	P35568	IRS1	P31749	AKT1	S415	S415L	415	Missense	central	0	yes	8.256	0.000	EPSD	COSMIC	7.780	Loss
AGC_Akt_AKT1_ST	P35568	IRS1	P31749	AKT1	S415	G418V	418	Missense	distal	3	no	8.256	8.257	EPSD	COSMIC;GDSC;CCLE	7.780	Up-regulation
AGC_Akt_AKT1_ST	P35568	IRS1	P31749	AKT1	S415	D422N	422	Missense	distal	7	no	8.256	8.297	EPSD	COSMIC	7.780	Up-regulation
AGC_Akt_AKT1_ST	P35568	IRS1	P31749	AKT1	S444	G451C	451	Missense	distal	7	no	7.937	7.888	EPSD	COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	P35568	IRS1	P31749	AKT1	S444	R439Q	439	Missense	distal	-5	no	7.937	3.710	EPSD	COSMIC	7.780	Loss
AGC_Akt_AKT1_ST	P35568	IRS1	P31749	AKT1	S444	D448E	448	Missense	distal	4	no	7.937	7.791	EPSD	COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	P35568	IRS1	P31749	AKT1	S444	S441Y	441	Missense	distal	-3	no	7.937	8.124	EPSD	COSMIC	7.780	Up-regulation
AGC_Akt_AKT1_ST	P35568	IRS1	P31749	AKT1	S444	S441F	441	Missense	distal	-3	no	7.937	10.119	EPSD	COSMIC	7.780	Up-regulation
AGC_Akt_AKT1_ST	P35568	IRS1	P31749	AKT1	S444	R443C	443	Missense	proximal	-1	no	7.937	7.867	EPSD	COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	P35568	IRS1	P31749	AKT1	S444	P447L	447	Missense	distal	3	no	7.937	7.921	EPSD	COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	P35568	IRS1	P31749	AKT1	S444	R443L	443	Missense	proximal	-1	no	7.937	7.898	EPSD	COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	P35568	IRS1	P31749	AKT1	S444	S444I	444	Missense	central	0	yes	7.937	0.000	EPSD	COSMIC	7.780	Loss
AGC_Akt_AKT1_ST	P35568	IRS1	P31749	AKT1	S444	S449P	449	Missense	distal	5	no	7.937	7.884	EPSD	COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	P35568	IRS1	P31749	AKT1	T446	G451C	451	Missense	distal	5	no	8.852	8.796	EPSD	COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	P35568	IRS1	P31749	AKT1	T446	R439Q	439	Missense	distal	-7	no	8.852	8.658	EPSD	COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	P35568	IRS1	P31749	AKT1	T446	D448E	448	Missense	proximal	2	no	8.852	9.262	EPSD	COSMIC	7.780	Up-regulation
AGC_Akt_AKT1_ST	P35568	IRS1	P31749	AKT1	T446	S441Y	441	Missense	distal	-5	no	8.852	8.714	EPSD	COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	P35568	IRS1	P31749	AKT1	T446	T453I	453	Missense	distal	7	no	8.852	8.744	EPSD	COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	P35568	IRS1	P31749	AKT1	T446	S441F	441	Missense	distal	-5	no	8.852	9.801	EPSD	COSMIC	7.780	Up-regulation
AGC_Akt_AKT1_ST	P35568	IRS1	P31749	AKT1	T446	R443C	443	Missense	distal	-3	no	8.852	2.679	EPSD	COSMIC	7.780	Loss
AGC_Akt_AKT1_ST	P35568	IRS1	P31749	AKT1	T446	P447L	447	Missense	proximal	1	no	8.852	9.106	EPSD	COSMIC	7.780	Up-regulation
AGC_Akt_AKT1_ST	P35568	IRS1	P31749	AKT1	T446	R443L	443	Missense	distal	-3	no	8.852	1.858	EPSD	COSMIC	7.780	Loss
AGC_Akt_AKT1_ST	P35568	IRS1	P31749	AKT1	T446	S444I	444	Missense	proximal	-2	no	8.852	7.611	EPSD	COSMIC	7.780	Loss
AGC_Akt_AKT1_ST	P35568	IRS1	P31749	AKT1	T446	S449P	449	Missense	distal	3	no	8.852	8.771	EPSD	COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	P35568	IRS1	P31749	AKT1	T525	T530A	530	Missense	distal	5	no	14.903	14.852	EPSD	COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	P35568	IRS1	P31749	AKT1	T525	R520L	520	Missense	distal	-5	no	14.903	10.777	EPSD	COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	P35568	IRS1	P31749	AKT1	T525	F521I	521	Missense	distal	-4	no	14.903	14.689	EPSD	COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	P35568	IRS1	P31749	AKT1	T525	H526Y	526	Missense	proximal	1	no	14.903	15.074	EPSD	COSMIC	7.780	Up-regulation
AGC_Akt_AKT1_ST	P35568	IRS1	P31749	AKT1	T525	G529D	529	Missense	distal	4	no	14.903	14.954	EPSD	COSMIC	7.780	Up-regulation
AGC_Akt_AKT1_ST	P35568	IRS1	P31749	AKT1	S527	T530A	530	Missense	distal	3	no	16.468	16.411	EPSD	COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	P35568	IRS1	P31749	AKT1	S527	R520L	520	Missense	distal	-7	no	16.468	16.179	EPSD	COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	P35568	IRS1	P31749	AKT1	S527	T533I	533	Missense	distal	6	no	16.468	16.283	EPSD	COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	P35568	IRS1	P31749	AKT1	S527	F521I	521	Missense	distal	-6	no	16.468	16.423	EPSD	COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	P35568	IRS1	P31749	AKT1	S527	H526Y	526	Missense	proximal	-1	no	16.468	16.476	EPSD	COSMIC	7.780	Up-regulation
AGC_Akt_AKT1_ST	P35568	IRS1	P31749	AKT1	S527	G529D	529	Missense	proximal	2	no	16.468	16.201	EPSD	COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	P35568	IRS1	P31749	AKT1	S574	P578S	578	Missense	distal	4	no	7.811	7.655	EPSD	COSMIC	7.780	Loss
AGC_Akt_AKT1_ST	P35568	IRS1	P31749	AKT1	S574	F576L	576	Missense	proximal	2	no	7.811	7.843	EPSD	COSMIC	7.780	Up-regulation
AGC_Akt_AKT1_ST	P35568	IRS1	P31749	AKT1	S603	H598R	598	Missense	distal	-5	no	12.032	15.127	EPSD	COSMIC	7.780	Up-regulation
AGC_Akt_AKT1_ST	P35568	IRS1	P31749	AKT1	S603	G596E	596	Missense	distal	-7	no	12.032	12.068	EPSD	COSMIC	7.780	Up-regulation
AGC_Akt_AKT1_ST	P35568	IRS1	P31749	AKT1	S603	H599Y	599	Missense	distal	-4	no	12.032	12.146	EPSD	COSMIC	7.780	Up-regulation
AGC_Akt_AKT1_ST	P35568	IRS1	P31749	AKT1	S603	H599Q	599	Missense	distal	-4	no	12.032	12.470	EPSD	COSMIC	7.780	Up-regulation
AGC_Akt_AKT1_ST	P35568	IRS1	P31749	AKT1	T605	H598R	598	Missense	distal	-7	no	9.252	9.553	EPSD	COSMIC	7.780	Up-regulation
AGC_Akt_AKT1_ST	P35568	IRS1	P31749	AKT1	T605	H599Y	599	Missense	distal	-6	no	9.252	9.277	EPSD	COSMIC	7.780	Up-regulation
AGC_Akt_AKT1_ST	P35568	IRS1	P31749	AKT1	T605	H599Q	599	Missense	distal	-6	no	9.252	9.286	EPSD	COSMIC	7.780	Up-regulation
AGC_Akt_AKT1_ST	P35568	IRS1	P31749	AKT1	S629	G628D	628	Missense	proximal	-1	no	11.601	11.583	PhosphoSitePlus	COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	P35568	IRS1	P31749	AKT1	S629	R626Q	626	Missense	distal	-3	no	11.601	4.390	PhosphoSitePlus	COSMIC	7.780	Loss
AGC_Akt_AKT1_ST	P35568	IRS1	P31749	AKT1	S629	V622M	622	Missense	distal	-7	no	11.601	11.663	PhosphoSitePlus	COSMIC	7.780	Up-regulation
AGC_Akt_AKT1_ST	P35568	IRS1	P31749	AKT1	S629	G630E	630	Missense	proximal	1	no	11.601	11.810	PhosphoSitePlus	COSMIC	7.780	Up-regulation
AGC_Akt_AKT1_ST	P35568	IRS1	P31749	AKT1	S792	Q787R	787	Missense	distal	-5	no	4.618	8.846	EPSD	COSMIC	7.780	Gain
AGC_Akt_AKT1_ST	P35568	IRS1	P31749	AKT1	T793	S792F	792	Missense	proximal	-1	no	10.368	10.333	EPSD	COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	P35568	IRS1	P31749	AKT1	T793	R790C	790	Missense	distal	-3	no	10.368	4.194	EPSD	COSMIC	7.780	Loss
AGC_Akt_AKT1_ST	P35568	IRS1	P31749	AKT1	T793	Q787R	787	Missense	distal	-6	no	10.368	10.452	EPSD	COSMIC	7.780	Up-regulation
AGC_Akt_AKT1_ST	P35568	IRS1	P31749	AKT1	S795	S792F	792	Missense	distal	-3	no	5.779	7.961	EPSD	COSMIC	7.780	Gain
AGC_Akt_AKT1_ST	P35568	IRS1	P31749	AKT1	T859	T859M	859	Missense	central	0	yes	8.975	0.000	EPSD	COSMIC	7.780	Loss
AGC_Akt_AKT1_ST	P35568	IRS1	P31749	AKT1	T859	L855P	855	Missense	distal	-4	no	8.975	9.363	EPSD	COSMIC	7.780	Up-regulation
AGC_Akt_AKT1_ST	P35568	IRS1	P31749	AKT1	T859	R857Q	857	Missense	proximal	-2	no	8.975	8.463	EPSD	COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	P35568	IRS1	P31749	AKT1	T859	G864W	864	Missense	distal	5	no	8.975	8.951	EPSD	COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	P35568	IRS1	P31749	AKT1	T859	R854L	854	Missense	distal	-5	no	8.975	4.849	EPSD	COSMIC	7.780	Loss
AGC_Akt_AKT1_ST	P35568	IRS1	P31749	AKT1	T859	P858H	858	Missense	proximal	-1	no	8.975	8.970	EPSD	COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	P35568	IRS1	P31749	AKT1	S862	T859M	859	Missense	distal	-3	no	8.757	8.273	EPSD	COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	P35568	IRS1	P31749	AKT1	S862	L855P	855	Missense	distal	-7	no	8.757	8.797	EPSD	COSMIC	7.780	Up-regulation
AGC_Akt_AKT1_ST	P35568	IRS1	P31749	AKT1	S862	R857Q	857	Missense	distal	-5	no	8.757	4.530	EPSD	COSMIC	7.780	Loss
AGC_Akt_AKT1_ST	P35568	IRS1	P31749	AKT1	S862	G864W	864	Missense	proximal	2	no	8.757	8.462	EPSD	COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	P35568	IRS1	P31749	AKT1	S862	P858H	858	Missense	distal	-4	no	8.757	8.520	EPSD	COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	P35568	IRS1	P31749	AKT1	S985	P983S	983	Missense	proximal	-2	no	9.896	10.720	EPSD	COSMIC	7.780	Up-regulation
AGC_Akt_AKT1_ST	P35568	IRS1	P31749	AKT1	S985	S985N	985	Missense	central	0	yes	9.896	0.000	EPSD	COSMIC	7.780	Loss
AGC_Akt_AKT1_ST	P35568	IRS1	P31749	AKT1	S985	M992K	992	Missense	distal	7	no	9.896	9.955	EPSD	COSMIC	7.780	Up-regulation
AGC_Akt_AKT1_ST	P35568	IRS1	P31749	AKT1	S1084	P1079S	1079	Missense	distal	-5	no	10.904	10.444	EPSD	COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	P35568	IRS1	P31749	AKT1	S1084	S1078I	1078	Missense	distal	-6	no	10.904	10.784	EPSD	COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	P35568	IRS1	P31749	AKT1	S1084	V1087A	1087	Missense	distal	3	no	10.904	10.936	EPSD	COSMIC	7.780	Up-regulation
AGC_Akt_AKT1_ST	P35568	IRS1	P31749	AKT1	S1084	R1081C	1081	Missense	distal	-3	no	10.904	4.730	EPSD	COSMIC	7.780	Loss
AGC_Akt_AKT1_ST	P35568	IRS1	P31749	AKT1	S1100	R1097W	1097	Missense	distal	-3	no	13.515	4.574	EPSD	COSMIC	7.780	Loss
AGC_Akt_AKT1_ST	P35568	IRS1	P31749	AKT1	S1100	E1102K	1102	Missense	proximal	2	no	13.515	13.720	EPSD	COSMIC	7.780	Up-regulation
AGC_Akt_AKT1_ST	P35568	IRS1	P31749	AKT1	S1101	R1097W	1097	Missense	distal	-4	no	16.825	15.276	EPSD	COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	P35568	IRS1	P31749	AKT1	S1101	E1102K	1102	Missense	proximal	1	no	16.825	16.989	EPSD	COSMIC	7.780	Up-regulation
AGC_Akt_AKT1_ST	P35568	IRS1	P31749	AKT1	T1103	R1097W	1097	Missense	distal	-6	no	7.892	7.744	EPSD	COSMIC	7.780	Loss
AGC_Akt_AKT1_ST	P35568	IRS1	P31749	AKT1	T1103	E1102K	1102	Missense	proximal	-1	no	7.892	7.913	EPSD	COSMIC	7.780	Up-regulation
AGC_Akt_AKT1_ST	P35568	IRS1	P31749	AKT1	S1105	E1102K	1102	Missense	distal	-3	no	6.422	8.473	EPSD	COSMIC	7.780	Gain
AGC_Akt_AKT1_ST	P35568	IRS1	P31749	AKT1	S1142	R1140C	1140	Missense	proximal	-2	no	8.598	7.134	EPSD	COSMIC;CCLE	7.780	Loss
AGC_Akt_AKT1_ST	P35568	IRS1	P31749	AKT1	S1143	R1140C	1140	Missense	distal	-3	no	12.388	6.214	EPSD	COSMIC;CCLE	7.780	Loss
AGC_Akt_AKT1_ST	P35568	IRS1	P31749	AKT1	S1213	H1208R	1208	Missense	distal	-5	no	6.584	9.678	EPSD	COSMIC	7.780	Gain
AGC_Akt_AKT1_ST	P35568	IRS1	P31749	AKT1	S1223	R1220C	1220	Missense	distal	-3	no	13.710	7.536	EPSD	COSMIC	7.780	Loss
AGC_Akt_AKT1_ST	P35568	IRS1	P31749	AKT1	S1223	D1225Y	1225	Missense	proximal	2	no	13.710	13.936	EPSD	COSMIC	7.780	Up-regulation
AGC_Akt_AKT1_ST	P35568	IRS1	P31749	AKT1	S1223	A1228V	1228	Missense	distal	5	no	13.710	13.701	EPSD	COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	P35568	IRS1	P31749	AKT1	S1223	E1224Q	1224	Missense	proximal	1	no	13.710	13.656	EPSD	COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	P35568	IRS1	P31749	AKT1	S1223	L1226V	1226	Missense	distal	3	no	13.710	13.718	EPSD	COSMIC	7.780	Up-regulation
AGC_Akt_AKT1_ST	P35568	IRS1	P31749	AKT1	S1231	D1225Y	1225	Missense	distal	-6	no	8.367	8.426	EPSD	COSMIC	7.780	Up-regulation
AGC_Akt_AKT1_ST	P35568	IRS1	P31749	AKT1	S1231	Q1235P	1235	Missense	distal	4	no	8.367	8.389	EPSD	COSMIC	7.780	Up-regulation
AGC_Akt_AKT1_ST	P35568	IRS1	P31749	AKT1	S1231	A1228V	1228	Missense	distal	-3	no	8.367	7.804	EPSD	COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	P35568	IRS1	P31749	AKT1	S1231	E1224Q	1224	Missense	distal	-7	no	8.367	8.378	EPSD	COSMIC	7.780	Up-regulation
AGC_Akt_AKT1_ST	P35568	IRS1	P31749	AKT1	S1231	L1226V	1226	Missense	distal	-5	no	8.367	8.178	EPSD	COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	Q16875	PFKFB3	P31749	AKT1	S211	S211L	211	Missense	central	0	yes	9.597	0.000	EPSD	COSMIC	7.780	Loss
AGC_Akt_AKT1_ST	Q16875	PFKFB3	P31749	AKT1	S211	S211P	211	Missense	central	0	yes	9.597	0.000	EPSD	COSMIC	7.780	Loss
AGC_Akt_AKT1_ST	Q16875	PFKFB3	P31749	AKT1	S211	S211R	211	Missense	central	0	yes	9.597	0.000	EPSD	COSMIC	7.780	Loss
AGC_Akt_AKT1_ST	Q16875	PFKFB3	P31749	AKT1	S211	S211N	211	Missense	central	0	yes	9.597	0.000	EPSD	COSMIC	7.780	Loss
AGC_Akt_AKT1_ST	Q16875	PFKFB3	P31749	AKT1	S280	E287D	287	Missense	distal	7	no	8.046	8.002	EPSD	COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	Q16875	PFKFB3	P31749	AKT1	T359	G360R	360	Missense	proximal	1	no	9.224	9.673	EPSD	COSMIC	7.780	Up-regulation
AGC_Akt_AKT1_ST	Q16875	PFKFB3	P31749	AKT1	T359	R356C	356	Missense	distal	-3	no	9.224	3.050	EPSD	COSMIC	7.780	Loss
AGC_Akt_AKT1_ST	Q16875	PFKFB3	P31749	AKT1	T359	Y354C	354	Missense	distal	-5	no	9.224	9.755	EPSD	COSMIC	7.780	Up-regulation
AGC_Akt_AKT1_ST	Q16875	PFKFB3	P31749	AKT1	S446	R443Q	443	Missense	distal	-3	no	10.569	3.358	EPSD	COSMIC	7.780	Loss
AGC_Akt_AKT1_ST	Q16875	PFKFB3	P31749	AKT1	S446	K451R	451	Missense	distal	5	no	10.569	10.575	EPSD	COSMIC	7.780	Up-regulation
AGC_Akt_AKT1_ST	Q16875	PFKFB3	P31749	AKT1	S446	K450E	450	Missense	distal	4	no	10.569	10.670	EPSD	COSMIC	7.780	Up-regulation
AGC_Akt_AKT1_ST	Q16875	PFKFB3	P31749	AKT1	S461	S467N	467	Missense	distal	6	no	12.705	12.637	PhosphoSitePlus	COSMIC;GDSC;CCLE	7.780	Down-regulation
AGC_Akt_AKT1_ST	Q16875	PFKFB3	P31749	AKT1	S461	S467L	467	Missense	distal	6	no	12.705	12.601	PhosphoSitePlus	COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	Q16875	PFKFB3	P31749	AKT1	T463	S467N	467	Missense	distal	4	no	8.557	8.666	EPSD	COSMIC;GDSC;CCLE	7.780	Up-regulation
AGC_Akt_AKT1_ST	Q16875	PFKFB3	P31749	AKT1	T463	S467L	467	Missense	distal	4	no	8.557	8.745	EPSD	COSMIC	7.780	Up-regulation
AGC_Akt_AKT1_ST	Q16875	PFKFB3	P31749	AKT1	S478	E481K	481	Missense	distal	3	no	13.716	13.760	EPSD	COSMIC	7.780	Up-regulation
AGC_Akt_AKT1_ST	Q15118	PDK1	P31749	AKT1	T346	R348H	348	Missense	proximal	2	no	14.110	13.749	PhosphoSitePlus	COSMIC;GDSC	7.780	Down-regulation
AGC_Akt_AKT1_ST	Q15118	PDK1	P31749	AKT1	T346	R343C	343	Missense	distal	-3	no	14.110	7.936	PhosphoSitePlus	COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	Q15118	PDK1	P31749	AKT1	T346	R348C	348	Missense	proximal	2	no	14.110	13.457	PhosphoSitePlus	COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	P29317	EPHA2	P31749	AKT1	S433	R428C	428	Missense	distal	-5	no	10.266	6.189	EPSD	COSMIC;GDSC;CCLE	7.780	Loss
AGC_Akt_AKT1_ST	P29317	EPHA2	P31749	AKT1	S433	V432I	432	Missense	proximal	-1	no	10.266	10.252	EPSD	COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	P29317	EPHA2	P31749	AKT1	S433	R428H	428	Missense	distal	-5	no	10.266	7.171	EPSD	COSMIC	7.780	Loss
AGC_Akt_AKT1_ST	P29317	EPHA2	P31749	AKT1	S897	V904G	904	Missense	distal	7	no	10.610	10.592	PhosphoSitePlus	COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	P29317	EPHA2	P31749	AKT1	S897	R890C	890	Missense	distal	-7	no	10.610	10.131	PhosphoSitePlus	COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	P29317	EPHA2	P31749	AKT1	S897	T898M	898	Missense	proximal	1	no	10.610	10.354	PhosphoSitePlus	COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	P29317	EPHA2	P31749	AKT1	S899	V904G	904	Missense	distal	5	no	9.398	9.395	EPSD	COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	P29317	EPHA2	P31749	AKT1	S899	T898M	898	Missense	proximal	-1	no	9.398	9.363	EPSD	COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	P29317	EPHA2	P31749	AKT1	S910	E911K	911	Missense	proximal	1	no	11.195	11.359	EPSD	COSMIC;CCLE	7.780	Up-regulation
AGC_Akt_AKT1_ST	P29317	EPHA2	P31749	AKT1	S910	V904G	904	Missense	distal	-6	no	11.195	11.192	EPSD	COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	P29317	EPHA2	P31749	AKT1	S910	T908M	908	Missense	proximal	-2	no	11.195	10.422	EPSD	COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	O15519	CFLAR	P31749	AKT1	S248	S248L	248	Missense	central	0	yes	9.004	0.000	EPSD	COSMIC;GDSC	7.780	Loss
AGC_Akt_AKT1_ST	O15519	CFLAR	P31749	AKT1	S248	P250A	250	Missense	proximal	2	no	9.004	8.964	EPSD	COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	O15519	CFLAR	P31749	AKT1	S273	D269G	269	Missense	distal	-4	no	8.098	8.657	PhosphoSitePlus	COSMIC	7.780	Up-regulation
AGC_Akt_AKT1_ST	P26358	DNMT1	P31749	AKT1	T12	P16L	16	Missense	distal	4	no	11.540	11.573	EPSD	COSMIC	7.780	Up-regulation
AGC_Akt_AKT1_ST	P26358	DNMT1	P31749	AKT1	T12	P11S	11	Missense	proximal	-1	no	11.540	11.569	EPSD	COSMIC	7.780	Up-regulation
AGC_Akt_AKT1_ST	P26358	DNMT1	P31749	AKT1	T12	A17T	17	Missense	distal	5	no	11.540	11.592	EPSD	COSMIC	7.780	Up-regulation
AGC_Akt_AKT1_ST	P26358	DNMT1	P31749	AKT1	S74	R69H	69	Missense	distal	-5	no	11.321	8.226	EPSD	COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	P26358	DNMT1	P31749	AKT1	S74	E71K	71	Missense	distal	-3	no	11.321	13.372	EPSD	COSMIC	7.780	Up-regulation
AGC_Akt_AKT1_ST	P26358	DNMT1	P31749	AKT1	S141	R140K	140	Missense	proximal	-1	no	10.414	10.410	EPSD	COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	P26358	DNMT1	P31749	AKT1	S141	R136C	136	Missense	distal	-5	no	10.414	6.337	EPSD	COSMIC	7.780	Loss
AGC_Akt_AKT1_ST	P26358	DNMT1	P31749	AKT1	S141	D144N	144	Missense	distal	3	no	10.414	10.469	EPSD	COSMIC	7.780	Up-regulation
AGC_Akt_AKT1_ST	P26358	DNMT1	P31749	AKT1	S143	R140K	140	Missense	distal	-3	no	11.970	7.450	PhosphoSitePlus	COSMIC	7.780	Loss
AGC_Akt_AKT1_ST	P26358	DNMT1	P31749	AKT1	S143	R136C	136	Missense	distal	-7	no	11.970	11.491	PhosphoSitePlus	COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	P26358	DNMT1	P31749	AKT1	S143	D144N	144	Missense	proximal	1	no	11.970	12.094	PhosphoSitePlus	COSMIC	7.780	Up-regulation
AGC_Akt_AKT1_ST	P26358	DNMT1	P31749	AKT1	T162	I167F	167	Missense	distal	5	no	10.663	10.687	EPSD	COSMIC	7.780	Up-regulation
AGC_Akt_AKT1_ST	P26358	DNMT1	P31749	AKT1	T162	T166I	166	Missense	distal	4	no	10.663	10.929	EPSD	COSMIC	7.780	Up-regulation
AGC_Akt_AKT1_ST	P26358	DNMT1	P31749	AKT1	T162	S161G	161	Missense	proximal	-1	no	10.663	10.633	EPSD	COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	P26358	DNMT1	P31749	AKT1	T162	T165I	165	Missense	distal	3	no	10.663	10.533	EPSD	COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	P26358	DNMT1	P31749	AKT1	T166	I167F	167	Missense	proximal	1	no	9.916	10.182	EPSD	COSMIC	7.780	Up-regulation
AGC_Akt_AKT1_ST	P26358	DNMT1	P31749	AKT1	T166	T166I	166	Missense	central	0	yes	9.916	0.000	EPSD	COSMIC	7.780	Loss
AGC_Akt_AKT1_ST	P26358	DNMT1	P31749	AKT1	T166	S161G	161	Missense	distal	-5	no	9.916	10.322	EPSD	COSMIC	7.780	Up-regulation
AGC_Akt_AKT1_ST	P26358	DNMT1	P31749	AKT1	T166	T165I	165	Missense	proximal	-1	no	9.916	9.860	EPSD	COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	P26358	DNMT1	P31749	AKT1	T166	H170D	170	Missense	distal	4	no	9.916	9.945	EPSD	COSMIC	7.780	Up-regulation
AGC_Akt_AKT1_ST	P26358	DNMT1	P31749	AKT1	T168	I167F	167	Missense	proximal	-1	no	8.038	8.053	EPSD	COSMIC	7.780	Up-regulation
AGC_Akt_AKT1_ST	P26358	DNMT1	P31749	AKT1	T168	T166I	166	Missense	proximal	-2	no	8.038	6.864	EPSD	COSMIC	7.780	Loss
AGC_Akt_AKT1_ST	P26358	DNMT1	P31749	AKT1	T168	S161G	161	Missense	distal	-7	no	8.038	7.852	EPSD	COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	P26358	DNMT1	P31749	AKT1	T168	T165I	165	Missense	distal	-3	no	8.038	7.979	EPSD	COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	P26358	DNMT1	P31749	AKT1	T168	P175S	175	Missense	distal	7	no	8.038	8.097	EPSD	COSMIC	7.780	Up-regulation
AGC_Akt_AKT1_ST	P26358	DNMT1	P31749	AKT1	T168	H170D	170	Missense	proximal	2	no	8.038	7.972	EPSD	COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	P26358	DNMT1	P31749	AKT1	S189	S189L	189	Missense	central	0	yes	10.378	0.000	EPSD	COSMIC	7.780	Loss
AGC_Akt_AKT1_ST	P26358	DNMT1	P31749	AKT1	S189	S192F	192	Missense	distal	3	no	10.378	10.280	EPSD	COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	P26358	DNMT1	P31749	AKT1	T208	R215T	215	Missense	distal	7	no	12.194	12.197	EPSD	COSMIC;CCLE	7.780	Up-regulation
AGC_Akt_AKT1_ST	P26358	DNMT1	P31749	AKT1	T208	R205H	205	Missense	distal	-3	no	12.194	7.496	EPSD	COSMIC	7.780	Loss
AGC_Akt_AKT1_ST	P26358	DNMT1	P31749	AKT1	T208	R215K	215	Missense	distal	7	no	12.194	12.187	EPSD	COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	P26358	DNMT1	P31749	AKT1	S209	R215T	215	Missense	distal	6	no	15.580	15.602	EPSD	COSMIC;CCLE	7.780	Up-regulation
AGC_Akt_AKT1_ST	P26358	DNMT1	P31749	AKT1	S209	P216L	216	Missense	distal	7	no	15.580	15.572	EPSD	COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	P26358	DNMT1	P31749	AKT1	S209	R205H	205	Missense	distal	-4	no	15.580	14.521	EPSD	COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	P26358	DNMT1	P31749	AKT1	S209	P216Q	216	Missense	distal	7	no	15.580	15.590	EPSD	COSMIC	7.780	Up-regulation
AGC_Akt_AKT1_ST	P26358	DNMT1	P31749	AKT1	S209	R215K	215	Missense	distal	6	no	15.580	15.592	EPSD	COSMIC	7.780	Up-regulation
AGC_Akt_AKT1_ST	P26358	DNMT1	P31749	AKT1	S227	T229M	229	Missense	proximal	2	no	9.927	9.585	EPSD	COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	P26358	DNMT1	P31749	AKT1	S227	S227A	227	Missense	central	0	yes	9.927	0.000	EPSD	COSMIC	7.780	Loss
AGC_Akt_AKT1_ST	P26358	DNMT1	P31749	AKT1	S227	R230C	230	Missense	distal	3	no	9.927	9.766	EPSD	COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	P26358	DNMT1	P31749	AKT1	S227	R230H	230	Missense	distal	3	no	9.927	9.843	EPSD	COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	P26358	DNMT1	P31749	AKT1	S227	S227L	227	Missense	central	0	yes	9.927	0.000	EPSD	COSMIC	7.780	Loss
AGC_Akt_AKT1_ST	P26358	DNMT1	P31749	AKT1	S227	G228E	228	Missense	proximal	1	no	9.927	10.136	EPSD	COSMIC	7.780	Up-regulation
AGC_Akt_AKT1_ST	P26358	DNMT1	P31749	AKT1	S227	E220Q	220	Missense	distal	-7	no	9.927	9.938	EPSD	COSMIC	7.780	Up-regulation
AGC_Akt_AKT1_ST	P26358	DNMT1	P31749	AKT1	S227	R224K	224	Missense	distal	-3	no	9.927	5.407	EPSD	COSMIC	7.780	Loss
AGC_Akt_AKT1_ST	P26358	DNMT1	P31749	AKT1	T229	T229M	229	Missense	central	0	yes	9.854	0.000	EPSD	COSMIC	7.780	Loss
AGC_Akt_AKT1_ST	P26358	DNMT1	P31749	AKT1	T229	S227A	227	Missense	proximal	-2	no	9.854	9.402	EPSD	COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	P26358	DNMT1	P31749	AKT1	T229	R230C	230	Missense	proximal	1	no	9.854	9.325	EPSD	COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	P26358	DNMT1	P31749	AKT1	T229	R230H	230	Missense	proximal	1	no	9.854	9.531	EPSD	COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	P26358	DNMT1	P31749	AKT1	T229	S227L	227	Missense	proximal	-2	no	9.854	8.997	EPSD	COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	P26358	DNMT1	P31749	AKT1	T229	E236D	236	Missense	distal	7	no	9.854	9.811	EPSD	COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	P26358	DNMT1	P31749	AKT1	T229	G228E	228	Missense	proximal	-1	no	9.854	9.869	EPSD	COSMIC	7.780	Up-regulation
AGC_Akt_AKT1_ST	P26358	DNMT1	P31749	AKT1	T229	R224K	224	Missense	distal	-5	no	9.854	7.457	EPSD	COSMIC	7.780	Loss
AGC_Akt_AKT1_ST	P26358	DNMT1	P31749	AKT1	S247	P252L	252	Missense	distal	5	no	12.892	12.879	EPSD	COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	P26358	DNMT1	P31749	AKT1	S247	R246Q	246	Missense	proximal	-1	no	12.892	12.860	EPSD	COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	P26358	DNMT1	P31749	AKT1	S247	P254H	254	Missense	distal	7	no	12.892	12.887	EPSD	COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	P26358	DNMT1	P31749	AKT1	S247	R246C	246	Missense	proximal	-1	no	12.892	12.822	EPSD	COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	P26358	DNMT1	P31749	AKT1	S247	R246H	246	Missense	proximal	-1	no	12.892	12.848	EPSD	COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	P26358	DNMT1	P31749	AKT1	T249	P252L	252	Missense	distal	3	no	15.139	15.123	EPSD	COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	P26358	DNMT1	P31749	AKT1	T249	R246Q	246	Missense	distal	-3	no	15.139	7.928	EPSD	COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	P26358	DNMT1	P31749	AKT1	T249	P254H	254	Missense	distal	5	no	15.139	15.126	EPSD	COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	P26358	DNMT1	P31749	AKT1	T249	R246C	246	Missense	distal	-3	no	15.139	8.966	EPSD	COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	P26358	DNMT1	P31749	AKT1	T249	R246H	246	Missense	distal	-3	no	15.139	10.440	EPSD	COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	P26358	DNMT1	P31749	AKT1	S288	K291N	291	Missense	distal	3	no	7.827	7.768	EPSD	COSMIC	7.780	Loss
AGC_Akt_AKT1_ST	P26358	DNMT1	P31749	AKT1	S288	R287K	287	Missense	proximal	-1	no	7.827	7.823	EPSD	COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	P26358	DNMT1	P31749	AKT1	S288	D282Y	282	Missense	distal	-6	no	7.827	7.887	EPSD	COSMIC	7.780	Up-regulation
AGC_Akt_AKT1_ST	P26358	DNMT1	P31749	AKT1	S288	Q289E	289	Missense	proximal	1	no	7.827	7.881	EPSD	COSMIC	7.780	Up-regulation
AGC_Akt_AKT1_ST	P26358	DNMT1	P31749	AKT1	S288	S288N	288	Missense	central	0	yes	7.827	0.000	EPSD	COSMIC	7.780	Loss
AGC_Akt_AKT1_ST	P26358	DNMT1	P31749	AKT1	S288	K284Q	284	Missense	distal	-4	no	7.827	7.219	EPSD	COSMIC	7.780	Loss
AGC_Akt_AKT1_ST	P26358	DNMT1	P31749	AKT1	S288	D282N	282	Missense	distal	-6	no	7.827	7.899	EPSD	COSMIC	7.780	Up-regulation
AGC_Akt_AKT1_ST	P26358	DNMT1	P31749	AKT1	T327	R325H	325	Missense	proximal	-2	no	11.335	10.475	EPSD	COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	P26358	DNMT1	P31749	AKT1	T327	R325L	325	Missense	proximal	-2	no	11.335	10.667	EPSD	COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	P26358	DNMT1	P31749	AKT1	T327	P332L	332	Missense	distal	5	no	11.335	11.322	EPSD	COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	P26358	DNMT1	P31749	AKT1	T327	E321G	321	Missense	distal	-6	no	11.335	11.302	EPSD	COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	P26358	DNMT1	P31749	AKT1	T328	R325H	325	Missense	distal	-3	no	16.306	11.607	EPSD	COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	P26358	DNMT1	P31749	AKT1	T328	R325L	325	Missense	distal	-3	no	16.306	9.312	EPSD	COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	P26358	DNMT1	P31749	AKT1	T328	P332L	332	Missense	distal	4	no	16.306	16.338	EPSD	COSMIC	7.780	Up-regulation
AGC_Akt_AKT1_ST	P26358	DNMT1	P31749	AKT1	T328	E321G	321	Missense	distal	-7	no	16.306	16.270	EPSD	COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	P26358	DNMT1	P31749	AKT1	T342	R339P	339	Missense	distal	-3	no	11.100	4.460	EPSD	COSMIC	7.780	Loss
AGC_Akt_AKT1_ST	P26358	DNMT1	P31749	AKT1	T342	A340T	340	Missense	proximal	-2	no	11.100	11.485	EPSD	COSMIC;CCLE	7.780	Up-regulation
AGC_Akt_AKT1_ST	P26358	DNMT1	P31749	AKT1	T342	R339H	339	Missense	distal	-3	no	11.100	6.401	EPSD	COSMIC	7.780	Loss
AGC_Akt_AKT1_ST	P26358	DNMT1	P31749	AKT1	S387	T382R	382	Missense	distal	-5	no	6.012	9.742	EPSD	COSMIC	7.780	Gain
AGC_Akt_AKT1_ST	P26358	DNMT1	P31749	AKT1	S549	E547D	547	Missense	proximal	-2	no	8.532	7.547	EPSD	COSMIC	7.780	Loss
AGC_Akt_AKT1_ST	P26358	DNMT1	P31749	AKT1	S549	R544H	544	Missense	distal	-5	no	8.532	5.437	EPSD	COSMIC	7.780	Loss
AGC_Akt_AKT1_ST	P26358	DNMT1	P31749	AKT1	S549	S549C	549	Missense	central	0	yes	8.532	0.000	EPSD	COSMIC	7.780	Loss
AGC_Akt_AKT1_ST	P26358	DNMT1	P31749	AKT1	S549	F556L	556	Missense	distal	7	no	8.532	8.539	EPSD	COSMIC	7.780	Up-regulation
AGC_Akt_AKT1_ST	P26358	DNMT1	P31749	AKT1	S549	A554T	554	Missense	distal	5	no	8.532	8.583	EPSD	COSMIC	7.780	Up-regulation
AGC_Akt_AKT1_ST	P26358	DNMT1	P31749	AKT1	S549	A554P	554	Missense	distal	5	no	8.532	8.530	EPSD	COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	P26358	DNMT1	P31749	AKT1	S878	P879S	879	Missense	proximal	1	no	10.775	10.930	EPSD	COSMIC;CCLE	7.780	Up-regulation
AGC_Akt_AKT1_ST	P26358	DNMT1	P31749	AKT1	S878	E877K	877	Missense	proximal	-1	no	10.775	10.796	EPSD	COSMIC	7.780	Up-regulation
AGC_Akt_AKT1_ST	P26358	DNMT1	P31749	AKT1	S878	T882I	882	Missense	distal	4	no	10.775	11.041	EPSD	COSMIC	7.780	Up-regulation
AGC_Akt_AKT1_ST	P26358	DNMT1	P31749	AKT1	S954	K951R	951	Missense	distal	-3	no	5.177	9.697	EPSD	COSMIC	7.780	Gain
AGC_Akt_AKT1_ST	P26358	DNMT1	P31749	AKT1	S977	S977F	977	Missense	central	0	yes	13.136	0.000	EPSD	COSMIC	7.780	Loss
AGC_Akt_AKT1_ST	P26358	DNMT1	P31749	AKT1	S977	H972Q	972	Missense	distal	-5	no	13.136	12.004	EPSD	COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	P26358	DNMT1	P31749	AKT1	S977	K981N	981	Missense	distal	4	no	13.136	13.268	EPSD	COSMIC	7.780	Up-regulation
AGC_Akt_AKT1_ST	P26358	DNMT1	P31749	AKT1	S977	D978H	978	Missense	proximal	1	no	13.136	13.171	EPSD	COSMIC	7.780	Up-regulation
AGC_Akt_AKT1_ST	P26358	DNMT1	P31749	AKT1	S977	R974W	974	Missense	distal	-3	no	13.136	4.196	EPSD	COSMIC	7.780	Loss
AGC_Akt_AKT1_ST	P26358	DNMT1	P31749	AKT1	S977	N984S	984	Missense	distal	7	no	13.136	13.172	EPSD	COSMIC	7.780	Up-regulation
AGC_Akt_AKT1_ST	P26358	DNMT1	P31749	AKT1	S977	D978N	978	Missense	proximal	1	no	13.136	13.261	EPSD	COSMIC	7.780	Up-regulation
AGC_Akt_AKT1_ST	P26358	DNMT1	P31749	AKT1	S977	R974C	974	Missense	distal	-3	no	13.136	6.963	EPSD	COSMIC	7.780	Loss
AGC_Akt_AKT1_ST	P26358	DNMT1	P31749	AKT1	S1095	A1091S	1091	Missense	distal	-4	no	8.006	8.728	EPSD	COSMIC	7.780	Up-regulation
AGC_Akt_AKT1_ST	P26358	DNMT1	P31749	AKT1	S1095	N1101K	1101	Missense	distal	6	no	8.006	8.084	EPSD	COSMIC	7.780	Up-regulation
AGC_Akt_AKT1_ST	P26358	DNMT1	P31749	AKT1	S1095	K1092T	1092	Missense	distal	-3	no	8.006	5.505	EPSD	COSMIC	7.780	Loss
AGC_Akt_AKT1_ST	P26358	DNMT1	P31749	AKT1	S1095	D1098V	1098	Missense	distal	3	no	8.006	8.028	EPSD	COSMIC	7.780	Up-regulation
AGC_Akt_AKT1_ST	P26358	DNMT1	P31749	AKT1	S1095	E1097Q	1097	Missense	proximal	2	no	8.006	7.905	EPSD	COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	P26358	DNMT1	P31749	AKT1	S1122	P1127Q	1127	Missense	distal	5	no	7.798	7.808	EPSD	COSMIC	7.780	Up-regulation
AGC_Akt_AKT1_ST	P26358	DNMT1	P31749	AKT1	S1122	P1127L	1127	Missense	distal	5	no	7.798	7.785	EPSD	COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	P26358	DNMT1	P31749	AKT1	S1122	S1128N	1128	Missense	distal	6	no	7.798	7.731	EPSD	COSMIC	7.780	Loss
AGC_Akt_AKT1_ST	P26358	DNMT1	P31749	AKT1	S1122	K1121N	1121	Missense	proximal	-1	no	7.798	7.774	EPSD	COSMIC	7.780	Loss
AGC_Akt_AKT1_ST	P26358	DNMT1	P31749	AKT1	S1122	G1118D	1118	Missense	distal	-4	no	7.798	7.240	EPSD	COSMIC	7.780	Loss
AGC_Akt_AKT1_ST	P26358	DNMT1	P31749	AKT1	S1122	E1129G	1129	Missense	distal	7	no	7.798	7.759	EPSD	COSMIC	7.780	Loss
AGC_Akt_AKT1_ST	P26358	DNMT1	P31749	AKT1	S1122	Q1123P	1123	Missense	proximal	1	no	7.798	7.793	EPSD	COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	P26358	DNMT1	P31749	AKT1	S1549	R1551Q	1551	Missense	proximal	2	no	10.709	10.592	EPSD	COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	P26358	DNMT1	P31749	AKT1	S1549	E1552D	1552	Missense	distal	3	no	10.709	10.639	EPSD	COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	P26358	DNMT1	P31749	AKT1	S1549	R1551W	1551	Missense	proximal	2	no	10.709	10.254	EPSD	COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	P26358	DNMT1	P31749	AKT1	S1549	R1555H	1555	Missense	distal	6	no	10.709	10.590	EPSD	COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	P26358	DNMT1	P31749	AKT1	S1549	R1555C	1555	Missense	distal	6	no	10.709	10.508	EPSD	COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	P26358	DNMT1	P31749	AKT1	S1605	A1600V	1600	Missense	distal	-5	no	9.912	9.452	EPSD	COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	P26358	DNMT1	P31749	AKT1	S1605	E1602Q	1602	Missense	distal	-3	no	9.912	9.273	EPSD	COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	P26358	DNMT1	P31749	AKT1	S1605	R1601Q	1601	Missense	distal	-4	no	9.912	9.291	EPSD	COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	P78362	SRPK2	P31749	AKT1	T492	T498A	498	Missense	distal	6	no	11.906	11.804	PhosphoSitePlus	COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	P78362	SRPK2	P31749	AKT1	T492	S497R	497	Missense	distal	5	no	11.906	11.914	PhosphoSitePlus	COSMIC	7.780	Up-regulation
AGC_Akt_AKT1_ST	P78362	SRPK2	P31749	AKT1	S494	T498A	498	Missense	distal	4	no	16.808	16.937	EPSD	COSMIC	7.780	Up-regulation
AGC_Akt_AKT1_ST	P78362	SRPK2	P31749	AKT1	S494	S497R	497	Missense	distal	3	no	16.808	16.791	EPSD	COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	P78362	SRPK2	P31749	AKT1	S496	T498A	498	Missense	proximal	2	no	10.250	9.949	EPSD	COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	P78362	SRPK2	P31749	AKT1	S496	S497R	497	Missense	proximal	1	no	10.250	10.395	EPSD	COSMIC	7.780	Up-regulation
AGC_Akt_AKT1_ST	P78362	SRPK2	P31749	AKT1	S616	R621L	621	Missense	distal	5	no	10.889	10.815	EPSD	COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	Q96KG9	SCYL1	P31749	AKT1	S41	G40V	40	Missense	proximal	-1	no	8.542	8.536	EPSD	COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	Q96KG9	SCYL1	P31749	AKT1	T469	A471V	471	Missense	proximal	2	no	13.647	13.485	PhosphoSitePlus	COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	Q96KG9	SCYL1	P31749	AKT1	S723	P716A	716	Missense	distal	-7	no	12.444	12.488	EPSD	COSMIC	7.780	Up-regulation
AGC_Akt_AKT1_ST	Q96KG9	SCYL1	P31749	AKT1	S723	E724D	724	Missense	proximal	1	no	12.444	12.326	EPSD	COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	Q96KG9	SCYL1	P31749	AKT1	S723	D717N	717	Missense	distal	-6	no	12.444	12.515	EPSD	COSMIC	7.780	Up-regulation
AGC_Akt_AKT1_ST	Q96KG9	SCYL1	P31749	AKT1	T748	A744T	744	Missense	distal	-4	no	9.472	10.250	EPSD	COSMIC	7.780	Up-regulation
AGC_Akt_AKT1_ST	Q96KG9	SCYL1	P31749	AKT1	T748	L742I	742	Missense	distal	-6	no	9.472	9.403	EPSD	COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	P15976	GATA1	P31749	AKT1	S116	D123Y	123	Missense	distal	7	no	12.092	12.126	EPSD	COSMIC	7.780	Up-regulation
AGC_Akt_AKT1_ST	P15976	GATA1	P31749	AKT1	S116	Q119R	119	Missense	distal	3	no	12.092	12.148	EPSD	COSMIC	7.780	Up-regulation
AGC_Akt_AKT1_ST	P15976	GATA1	P31749	AKT1	S116	R113S	113	Missense	distal	-3	no	12.092	4.315	EPSD	COSMIC	7.780	Loss
AGC_Akt_AKT1_ST	P15976	GATA1	P31749	AKT1	S116	R113C	113	Missense	distal	-3	no	12.092	5.918	EPSD	COSMIC;GDSC;CCLE	7.780	Loss
AGC_Akt_AKT1_ST	P15976	GATA1	P31749	AKT1	S116	R113L	113	Missense	distal	-3	no	12.092	5.098	EPSD	COSMIC	7.780	Loss
AGC_Akt_AKT1_ST	P15976	GATA1	P31749	AKT1	S116	R113H	113	Missense	distal	-3	no	12.092	7.393	EPSD	COSMIC	7.780	Loss
AGC_Akt_AKT1_ST	P15976	GATA1	P31749	AKT1	S116	V109L	109	Missense	distal	-7	no	12.092	12.136	EPSD	COSMIC	7.780	Up-regulation
AGC_Akt_AKT1_ST	P15976	GATA1	P31749	AKT1	S129	G126R	126	Missense	distal	-3	no	5.831	12.587	EPSD	COSMIC	7.780	Gain
AGC_Akt_AKT1_ST	P15976	GATA1	P31749	AKT1	S131	G126R	126	Missense	distal	-5	no	5.193	9.258	EPSD	COSMIC	7.780	Gain
AGC_Akt_AKT1_ST	P15976	GATA1	P31749	AKT1	S142	E139K	139	Missense	distal	-3	no	6.924	8.975	EPSD	COSMIC	7.780	Gain
AGC_Akt_AKT1_ST	P15976	GATA1	P31749	AKT1	T256	R253W	253	Missense	distal	-3	no	10.228	1.288	EPSD	COSMIC	7.780	Loss
AGC_Akt_AKT1_ST	P15976	GATA1	P31749	AKT1	T256	G255R	255	Missense	proximal	-1	no	10.228	10.268	EPSD	COSMIC;GDSC;CCLE	7.780	Up-regulation
AGC_Akt_AKT1_ST	P15976	GATA1	P31749	AKT1	T256	A254E	254	Missense	proximal	-2	no	10.228	10.272	EPSD	COSMIC;GDSC;CCLE	7.780	Up-regulation
AGC_Akt_AKT1_ST	P15976	GATA1	P31749	AKT1	T256	R253P	253	Missense	distal	-3	no	10.228	3.589	EPSD	COSMIC	7.780	Loss
AGC_Akt_AKT1_ST	P15976	GATA1	P31749	AKT1	S310	K308R	308	Missense	proximal	-2	no	17.117	16.678	PhosphoSitePlus	COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	P15976	GATA1	P31749	AKT1	S310	K315N	315	Missense	distal	5	no	17.117	17.081	PhosphoSitePlus	COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	P15976	GATA1	P31749	AKT1	S310	R307C	307	Missense	distal	-3	no	17.117	10.943	PhosphoSitePlus	COSMIC;CCLE	7.780	Down-regulation
AGC_Akt_AKT1_ST	P15976	GATA1	P31749	AKT1	S310	N306S	306	Missense	distal	-4	no	17.117	17.684	PhosphoSitePlus	COSMIC	7.780	Up-regulation
AGC_Akt_AKT1_ST	P15976	GATA1	P31749	AKT1	S310	K314E	314	Missense	distal	4	no	17.117	17.218	PhosphoSitePlus	COSMIC	7.780	Up-regulation
AGC_Akt_AKT1_ST	P15976	GATA1	P31749	AKT1	S310	R317L	317	Missense	distal	7	no	17.117	17.043	PhosphoSitePlus	COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	P15976	GATA1	P31749	AKT1	S310	G313E	313	Missense	distal	3	no	17.117	17.167	PhosphoSitePlus	COSMIC	7.780	Up-regulation
AGC_Akt_AKT1_ST	P15976	GATA1	P31749	AKT1	S319	S319C	319	Missense	central	0	yes	10.053	0.000	EPSD	COSMIC	7.780	Loss
AGC_Akt_AKT1_ST	P15976	GATA1	P31749	AKT1	S319	G325E	325	Missense	distal	6	no	10.053	10.100	EPSD	COSMIC	7.780	Up-regulation
AGC_Akt_AKT1_ST	P15976	GATA1	P31749	AKT1	S319	A326T	326	Missense	distal	7	no	10.053	10.114	EPSD	COSMIC	7.780	Up-regulation
AGC_Akt_AKT1_ST	P15976	GATA1	P31749	AKT1	S319	K315N	315	Missense	distal	-4	no	10.053	9.414	EPSD	COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	P15976	GATA1	P31749	AKT1	S319	K314E	314	Missense	distal	-5	no	10.053	8.356	EPSD	COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	P15976	GATA1	P31749	AKT1	S319	G323D	323	Missense	distal	4	no	10.053	10.105	EPSD	COSMIC	7.780	Up-regulation
AGC_Akt_AKT1_ST	P15976	GATA1	P31749	AKT1	S319	L321V	321	Missense	proximal	2	no	10.053	10.061	EPSD	COSMIC	7.780	Up-regulation
AGC_Akt_AKT1_ST	P15976	GATA1	P31749	AKT1	S319	G318S	318	Missense	proximal	-1	no	10.053	10.083	EPSD	COSMIC	7.780	Up-regulation
AGC_Akt_AKT1_ST	P15976	GATA1	P31749	AKT1	S319	R317L	317	Missense	proximal	-2	no	10.053	9.385	EPSD	COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	P15976	GATA1	P31749	AKT1	S319	G313E	313	Missense	distal	-6	no	10.053	10.087	EPSD	COSMIC	7.780	Up-regulation
AGC_Akt_AKT1_ST	P15976	GATA1	P31749	AKT1	S320	S319C	319	Missense	proximal	-1	no	13.443	13.383	EPSD	COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	P15976	GATA1	P31749	AKT1	S320	G325E	325	Missense	distal	5	no	13.443	13.473	EPSD	COSMIC	7.780	Up-regulation
AGC_Akt_AKT1_ST	P15976	GATA1	P31749	AKT1	S320	A326T	326	Missense	distal	6	no	13.443	13.546	EPSD	COSMIC	7.780	Up-regulation
AGC_Akt_AKT1_ST	P15976	GATA1	P31749	AKT1	S320	K315N	315	Missense	distal	-5	no	13.443	11.356	EPSD	COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	P15976	GATA1	P31749	AKT1	S320	K314E	314	Missense	distal	-6	no	13.443	13.376	EPSD	COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	P15976	GATA1	P31749	AKT1	S320	A327V	327	Missense	distal	7	no	13.443	13.439	EPSD	COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	P15976	GATA1	P31749	AKT1	S320	G323D	323	Missense	distal	3	no	13.443	13.422	EPSD	COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	P15976	GATA1	P31749	AKT1	S320	L321V	321	Missense	proximal	1	no	13.443	13.343	EPSD	COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	P15976	GATA1	P31749	AKT1	S320	G318S	318	Missense	proximal	-2	no	13.443	14.138	EPSD	COSMIC	7.780	Up-regulation
AGC_Akt_AKT1_ST	P15976	GATA1	P31749	AKT1	S320	R317L	317	Missense	distal	-3	no	13.443	6.449	EPSD	COSMIC	7.780	Loss
AGC_Akt_AKT1_ST	P15976	GATA1	P31749	AKT1	S320	G313E	313	Missense	distal	-7	no	13.443	13.479	EPSD	COSMIC	7.780	Up-regulation
AGC_Akt_AKT1_ST	Q99418	CYTH2	P31749	AKT1	T276	G270W	270	Missense	distal	-6	no	11.605	11.571	PhosphoSitePlus	COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	Q99418	CYTH2	P31749	AKT1	T276	T276M	276	Missense	central	0	yes	11.605	0.000	PhosphoSitePlus	COSMIC	7.780	Loss
AGC_Akt_AKT1_ST	Q99418	CYTH2	P31749	AKT1	T276	W281L	281	Missense	distal	5	no	11.605	11.626	PhosphoSitePlus	COSMIC	7.780	Up-regulation
AGC_Akt_AKT1_ST	Q99418	CYTH2	P31749	AKT1	T276	R273L	273	Missense	distal	-3	no	11.605	4.611	PhosphoSitePlus	COSMIC	7.780	Loss
AGC_Akt_AKT1_ST	Q99418	CYTH2	P31749	AKT1	T276	R273W	273	Missense	distal	-3	no	11.605	2.665	PhosphoSitePlus	COSMIC	7.780	Loss
AGC_Akt_AKT1_ST	Q99418	CYTH2	P31749	AKT1	T276	G272S	272	Missense	distal	-4	no	11.605	12.334	PhosphoSitePlus	COSMIC	7.780	Up-regulation
AGC_Akt_AKT1_ST	Q99418	CYTH2	P31749	AKT1	S392	K388M	388	Missense	distal	-4	no	15.149	14.167	EPSD	COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	Q99418	CYTH2	P31749	AKT1	S392	I391S	391	Missense	proximal	-1	no	15.149	15.198	EPSD	COSMIC	7.780	Up-regulation
AGC_Akt_AKT1_ST	Q99502	EYA1	P31749	AKT1	S299	G298C	298	Missense	proximal	-1	no	16.579	16.548	PhosphoSitePlus	COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	Q99502	EYA1	P31749	AKT1	S299	R297G	297	Missense	proximal	-2	no	16.579	16.073	PhosphoSitePlus	COSMIC;GDSC;CCLE	7.780	Down-regulation
AGC_Akt_AKT1_ST	Q99502	EYA1	P31749	AKT1	S299	R297Q	297	Missense	proximal	-2	no	16.579	16.066	PhosphoSitePlus	COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	Q99502	EYA1	P31749	AKT1	S299	R304H	304	Missense	distal	5	no	16.579	16.505	PhosphoSitePlus	COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	Q99502	EYA1	P31749	AKT1	S299	L295S	295	Missense	distal	-4	no	16.579	17.703	PhosphoSitePlus	COSMIC	7.780	Up-regulation
AGC_Akt_AKT1_ST	Q99502	EYA1	P31749	AKT1	S299	R296G	296	Missense	distal	-3	no	16.579	9.823	PhosphoSitePlus	COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	Q99502	EYA1	P31749	AKT1	S299	R296Q	296	Missense	distal	-3	no	16.579	9.368	PhosphoSitePlus	COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	Q99502	EYA1	P31749	AKT1	S299	R304G	304	Missense	distal	5	no	16.579	16.509	PhosphoSitePlus	COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	Q99502	EYA1	P31749	AKT1	S314	D318N	318	Missense	distal	4	no	7.980	7.865	EPSD	COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	Q99502	EYA1	P31749	AKT1	S314	P317Q	317	Missense	distal	3	no	7.980	7.989	EPSD	COSMIC	7.780	Up-regulation
AGC_Akt_AKT1_ST	Q99502	EYA1	P31749	AKT1	S314	D320E	320	Missense	distal	6	no	7.980	8.071	EPSD	COSMIC	7.780	Up-regulation
AGC_Akt_AKT1_ST	Q99502	EYA1	P31749	AKT1	S314	S319F	319	Missense	distal	5	no	7.980	7.908	EPSD	COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	Q99502	EYA1	P31749	AKT1	S314	S314A	314	Missense	central	0	yes	7.980	0.000	EPSD	COSMIC	7.780	Loss
AGC_Akt_AKT1_ST	Q99502	EYA1	P31749	AKT1	S314	N311K	311	Missense	distal	-3	no	7.980	10.937	EPSD	COSMIC	7.780	Up-regulation
AGC_Akt_AKT1_ST	Q99502	EYA1	P31749	AKT1	S314	P316Q	316	Missense	proximal	2	no	7.980	8.027	EPSD	COSMIC	7.780	Up-regulation
AGC_Akt_AKT1_ST	Q99502	EYA1	P31749	AKT1	S314	P315S	315	Missense	proximal	1	no	7.980	8.136	EPSD	COSMIC	7.780	Up-regulation
AGC_Akt_AKT1_ST	Q99502	EYA1	P31749	AKT1	S314	R308G	308	Missense	distal	-6	no	7.980	7.866	EPSD	COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	Q99502	EYA1	P31749	AKT1	S314	S314F	314	Missense	central	0	yes	7.980	0.000	EPSD	COSMIC	7.780	Loss
AGC_Akt_AKT1_ST	Q99502	EYA1	P31749	AKT1	S314	S314Y	314	Missense	central	0	yes	7.980	0.000	EPSD	COSMIC	7.780	Loss
AGC_Akt_AKT1_ST	Q99502	EYA1	P31749	AKT1	S314	D318H	318	Missense	distal	4	no	7.980	7.951	EPSD	COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	Q99502	EYA1	P31749	AKT1	S314	D318Y	318	Missense	distal	4	no	7.980	7.891	EPSD	COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	Q99502	EYA1	P31749	AKT1	S314	P315T	315	Missense	proximal	1	no	7.980	8.329	EPSD	COSMIC	7.780	Up-regulation
AGC_Akt_AKT1_ST	P17542	TAL1	P31749	AKT1	S7	S7N	7	Missense	central	0	yes	12.747	0.000	EPSD	COSMIC	7.780	Loss
AGC_Akt_AKT1_ST	P17542	TAL1	P31749	AKT1	S7	R11H	11	Missense	distal	4	no	12.747	12.932	EPSD	COSMIC	7.780	Up-regulation
AGC_Akt_AKT1_ST	P17542	TAL1	P31749	AKT1	S139	Q142K	142	Missense	distal	3	no	9.657	9.732	EPSD	COSMIC	7.780	Up-regulation
AGC_Akt_AKT1_ST	P17542	TAL1	P31749	AKT1	S172	R169K	169	Missense	distal	-3	no	11.400	6.880	EPSD	COSMIC	7.780	Loss
AGC_Akt_AKT1_ST	P17542	TAL1	P31749	AKT1	S172	M176I	176	Missense	distal	4	no	11.400	11.498	EPSD	COSMIC	7.780	Up-regulation
AGC_Akt_AKT1_ST	P17542	TAL1	P31749	AKT1	S172	E175K	175	Missense	distal	3	no	11.400	11.444	EPSD	COSMIC	7.780	Up-regulation
AGC_Akt_AKT1_ST	P17542	TAL1	P31749	AKT1	S172	S172Y	172	Missense	central	0	yes	11.400	0.000	EPSD	COSMIC	7.780	Loss
AGC_Akt_AKT1_ST	P17542	TAL1	P31749	AKT1	S172	T179S	179	Missense	distal	7	no	11.400	11.390	EPSD	COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	P17542	TAL1	P31749	AKT1	S172	P171H	171	Missense	proximal	-1	no	11.400	11.395	EPSD	COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	P17542	TAL1	P31749	AKT1	T216	P218H	218	Missense	proximal	2	no	8.004	7.807	EPSD	COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	P17542	TAL1	P31749	AKT1	T216	E209K	209	Missense	distal	-7	no	8.004	8.197	EPSD	COSMIC	7.780	Up-regulation
AGC_Akt_AKT1_ST	P17542	TAL1	P31749	AKT1	T216	R211C	211	Missense	distal	-5	no	8.004	3.927	EPSD	COSMIC	7.780	Loss
AGC_Akt_AKT1_ST	P17542	TAL1	P31749	AKT1	S224	P218H	218	Missense	distal	-6	no	8.208	8.188	EPSD	COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	P17542	TAL1	P31749	AKT1	S224	R230H	230	Missense	distal	6	no	8.208	8.089	EPSD	COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	P17542	TAL1	P31749	AKT1	S224	K225M	225	Missense	proximal	1	no	8.208	8.077	EPSD	COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	P17542	TAL1	P31749	AKT1	T256	Q252E	252	Missense	distal	-4	no	11.600	11.623	EPSD	COSMIC	7.780	Up-regulation
AGC_Akt_AKT1_ST	P17542	TAL1	P31749	AKT1	T256	G263R	263	Missense	distal	7	no	11.600	11.680	EPSD	COSMIC	7.780	Up-regulation
AGC_Akt_AKT1_ST	P17542	TAL1	P31749	AKT1	S316	R315H	315	Missense	proximal	-1	no	8.110	8.065	EPSD	COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	P17542	TAL1	P31749	AKT1	S316	R315L	315	Missense	proximal	-1	no	8.110	8.071	EPSD	COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	P17542	TAL1	P31749	AKT1	S316	A314T	314	Missense	proximal	-2	no	8.110	8.495	EPSD	COSMIC;CCLE	7.780	Up-regulation
AGC_Akt_AKT1_ST	P17542	TAL1	P31749	AKT1	S316	T313M	313	Missense	distal	-3	no	8.110	7.626	EPSD	COSMIC	7.780	Loss
AGC_Akt_AKT1_ST	Q92934	BAD	P31749	AKT1	S25	A27T	27	Missense	proximal	2	no	8.979	9.280	EPSD	COSMIC;GDSC;CCLE	7.780	Up-regulation
AGC_Akt_AKT1_ST	Q92934	BAD	P31749	AKT1	S75	A78E	78	Missense	distal	3	no	15.295	15.312	EPSD	COSMIC	7.780	Up-regulation
AGC_Akt_AKT1_ST	Q92934	BAD	P31749	AKT1	S97	P102L	102	Missense	distal	5	no	10.874	10.860	EPSD	COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	Q92934	BAD	P31749	AKT1	S97	S97P	97	Missense	central	0	yes	10.874	0.000	EPSD	COSMIC	7.780	Loss
AGC_Akt_AKT1_ST	Q92934	BAD	P31749	AKT1	S97	R98H	98	Missense	proximal	1	no	10.874	10.551	EPSD	COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	Q92934	BAD	P31749	AKT1	S97	P101S	101	Missense	distal	4	no	10.874	10.718	EPSD	COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	Q92934	BAD	P31749	AKT1	S99	P102L	102	Missense	distal	3	no	15.195	15.178	PhosphoSitePlus	COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	Q92934	BAD	P31749	AKT1	S99	S97P	97	Missense	proximal	-2	no	15.195	14.370	PhosphoSitePlus	COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	Q92934	BAD	P31749	AKT1	S99	R98H	98	Missense	proximal	-1	no	15.195	15.150	PhosphoSitePlus	COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	Q92934	BAD	P31749	AKT1	S99	P101S	101	Missense	proximal	2	no	15.195	15.531	PhosphoSitePlus	COSMIC	7.780	Up-regulation
AGC_Akt_AKT1_ST	Q92934	BAD	P31749	AKT1	S118	S124F	124	Missense	distal	6	no	10.696	10.577	EPSD	COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	Q92934	BAD	P31749	AKT1	S134	K127N	127	Missense	distal	-7	no	11.762	11.605	EPSD	COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	Q92934	BAD	P31749	AKT1	S134	K133N	133	Missense	proximal	-1	no	11.762	11.738	EPSD	COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	Q92934	BAD	P31749	AKT1	S145	W147R	147	Missense	proximal	2	no	9.942	10.397	EPSD	COSMIC	7.780	Up-regulation
AGC_Akt_AKT1_ST	Q92934	BAD	P31749	AKT1	S153	W147R	147	Missense	distal	-6	no	8.003	8.151	EPSD	COSMIC	7.780	Up-regulation
AGC_Akt_AKT1_ST	Q92934	BAD	P31749	AKT1	S164	R161S	161	Missense	distal	-3	no	13.174	5.398	EPSD	COSMIC;GDSC	7.780	Loss
AGC_Akt_AKT1_ST	Q92934	BAD	P31749	AKT1	S164	P166S	166	Missense	proximal	2	no	13.174	13.510	EPSD	COSMIC	7.780	Up-regulation
AGC_Akt_AKT1_ST	Q92934	BAD	P31749	AKT1	S164	R161G	161	Missense	distal	-3	no	13.174	6.418	EPSD	COSMIC	7.780	Loss
AGC_Akt_AKT1_ST	P09651	HNRNPA1	P31749	AKT1	S6	S6Y	6	Missense	central	0	yes	9.809	0.000	EPSD	COSMIC	7.780	Loss
AGC_Akt_AKT1_ST	P09651	HNRNPA1	P31749	AKT1	S6	E5K	5	Missense	proximal	-1	no	9.809	9.830	EPSD	COSMIC	7.780	Up-regulation
AGC_Akt_AKT1_ST	P09651	HNRNPA1	P31749	AKT1	S22	G19R	19	Missense	distal	-3	no	6.405	13.161	EPSD	COSMIC	7.780	Gain
AGC_Akt_AKT1_ST	P09651	HNRNPA1	P31749	AKT1	S197	G203C	203	Missense	distal	6	no	10.758	10.661	EPSD	COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	P09651	HNRNPA1	P31749	AKT1	S199	G203C	203	Missense	distal	4	no	17.470	17.641	PhosphoSitePlus	COSMIC	7.780	Up-regulation
AGC_Akt_AKT1_ST	P09651	HNRNPA1	P31749	AKT1	S360	G358S	358	Missense	proximal	-2	no	7.681	8.376	EPSD	COSMIC	7.780	Gain
AGC_Akt_AKT1_ST	P09651	HNRNPA1	P31749	AKT1	S360	G356R	356	Missense	distal	-4	no	7.681	8.496	EPSD	COSMIC	7.780	Gain
AGC_Akt_AKT1_ST	P09651	HNRNPA1	P31749	AKT1	S361	G358S	358	Missense	distal	-3	no	8.142	7.122	EPSD	COSMIC	7.780	Loss
AGC_Akt_AKT1_ST	P09651	HNRNPA1	P31749	AKT1	S361	G356R	356	Missense	distal	-5	no	8.142	12.207	EPSD	COSMIC	7.780	Up-regulation
AGC_Akt_AKT1_ST	P09651	HNRNPA1	P31749	AKT1	S361	S362N	362	Missense	proximal	1	no	8.142	8.054	EPSD	COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	P09651	HNRNPA1	P31749	AKT1	S361	G355V	355	Missense	distal	-6	no	8.142	8.146	EPSD	COSMIC	7.780	Up-regulation
AGC_Akt_AKT1_ST	P09651	HNRNPA1	P31749	AKT1	S361	Y366C	366	Missense	distal	5	no	8.142	8.067	EPSD	COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	P09651	HNRNPA1	P31749	AKT1	S361	G358V	358	Missense	distal	-3	no	8.142	8.033	EPSD	COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	P09651	HNRNPA1	P31749	AKT1	S362	G358S	358	Missense	distal	-4	no	8.009	8.738	EPSD	COSMIC	7.780	Up-regulation
AGC_Akt_AKT1_ST	P09651	HNRNPA1	P31749	AKT1	S362	G356R	356	Missense	distal	-6	no	8.009	8.123	EPSD	COSMIC	7.780	Up-regulation
AGC_Akt_AKT1_ST	P09651	HNRNPA1	P31749	AKT1	S362	S362N	362	Missense	central	0	yes	8.009	0.000	EPSD	COSMIC	7.780	Loss
AGC_Akt_AKT1_ST	P09651	HNRNPA1	P31749	AKT1	S362	G355V	355	Missense	distal	-7	no	8.009	7.917	EPSD	COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	P09651	HNRNPA1	P31749	AKT1	S362	Y366C	366	Missense	distal	4	no	8.009	8.218	EPSD	COSMIC	7.780	Up-regulation
AGC_Akt_AKT1_ST	P09651	HNRNPA1	P31749	AKT1	S362	G358V	358	Missense	distal	-4	no	8.009	7.644	EPSD	COSMIC	7.780	Loss
AGC_Akt_AKT1_ST	P09651	HNRNPA1	P31749	AKT1	S363	G356R	356	Missense	distal	-7	no	7.745	7.987	EPSD	COSMIC	7.780	Gain
AGC_Akt_AKT1_ST	P84022	SMAD3	P31749	AKT1	S37	E32R	32	Missense	distal	-5	no	5.328	9.423	EPSD	COSMIC	7.780	Gain
AGC_Akt_AKT1_ST	P84022	SMAD3	P31749	AKT1	T132	H126R	126	Missense	distal	-6	no	9.972	10.090	EPSD	COSMIC	7.780	Up-regulation
AGC_Akt_AKT1_ST	P84022	SMAD3	P31749	AKT1	T132	P137L	137	Missense	distal	5	no	9.972	9.958	EPSD	COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	P84022	SMAD3	P31749	AKT1	T132	V134A	134	Missense	proximal	2	no	9.972	10.134	EPSD	COSMIC	7.780	Up-regulation
AGC_Akt_AKT1_ST	P84022	SMAD3	P31749	AKT1	T132	V138L	138	Missense	distal	6	no	9.972	9.982	EPSD	COSMIC	7.780	Up-regulation
AGC_Akt_AKT1_ST	P84022	SMAD3	P31749	AKT1	T132	P136R	136	Missense	distal	4	no	9.972	9.827	EPSD	COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	P84022	SMAD3	P31749	AKT1	T132	P133L	133	Missense	proximal	1	no	9.972	10.225	EPSD	COSMIC	7.780	Up-regulation
AGC_Akt_AKT1_ST	P84022	SMAD3	P31749	AKT1	T388	S391R	391	Missense	distal	3	no	10.153	10.137	EPSD	COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	P84022	SMAD3	P31749	AKT1	T388	G381E	381	Missense	distal	-7	no	10.153	10.189	EPSD	COSMIC	7.780	Up-regulation
AGC_Akt_AKT1_ST	P84022	SMAD3	P31749	AKT1	T412	D408Y	408	Missense	distal	-4	no	7.628	8.056	EPSD	COSMIC	7.780	Gain
AGC_Akt_AKT1_ST	P84022	SMAD3	P31749	AKT1	S423	S423G	423	Missense	central	0	yes	12.093	0.000	EPSD	COSMIC	7.780	Loss
AGC_Akt_AKT1_ST	P84022	SMAD3	P31749	AKT1	S423	S423I	423	Missense	central	0	yes	12.093	0.000	EPSD	COSMIC	7.780	Loss
AGC_Akt_AKT1_ST	P84022	SMAD3	P31749	AKT1	S423	S422Y	422	Missense	proximal	-1	no	12.093	12.067	EPSD	COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	P84022	SMAD3	P31749	AKT1	S423	C421Y	421	Missense	proximal	-2	no	12.093	12.823	EPSD	COSMIC	7.780	Up-regulation
AGC_Akt_AKT1_ST	P84022	SMAD3	P31749	AKT1	S423	R420C	420	Missense	distal	-3	no	12.093	5.919	EPSD	COSMIC	7.780	Loss
AGC_Akt_AKT1_ST	P84022	SMAD3	P31749	AKT1	S425	S423G	423	Missense	proximal	-2	no	9.123	8.428	EPSD	COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	P84022	SMAD3	P31749	AKT1	S425	S423I	423	Missense	proximal	-2	no	9.123	7.882	EPSD	COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	P84022	SMAD3	P31749	AKT1	S425	S422Y	422	Missense	distal	-3	no	9.123	9.310	EPSD	COSMIC	7.780	Up-regulation
AGC_Akt_AKT1_ST	P84022	SMAD3	P31749	AKT1	S425	C421Y	421	Missense	distal	-4	no	9.123	9.857	EPSD	COSMIC	7.780	Up-regulation
AGC_Akt_AKT1_ST	P84022	SMAD3	P31749	AKT1	S425	R420C	420	Missense	distal	-5	no	9.123	5.046	EPSD	COSMIC	7.780	Loss
AGC_Akt_AKT1_ST	P18031	PTPN1	P31749	AKT1	S50	I57V	57	Missense	distal	7	no	15.185	15.228	PhosphoSitePlus	COSMIC;GDSC;CCLE	7.780	Up-regulation
AGC_Akt_AKT1_ST	P18031	PTPN1	P31749	AKT1	S50	F52L	52	Missense	proximal	2	no	15.185	15.217	PhosphoSitePlus	COSMIC	7.780	Up-regulation
AGC_Akt_AKT1_ST	P18031	PTPN1	P31749	AKT1	S203	V198F	198	Missense	distal	-5	no	7.285	8.078	EPSD	COSMIC	7.780	Gain
AGC_Akt_AKT1_ST	P18031	PTPN1	P31749	AKT1	S203	E200K	200	Missense	distal	-3	no	7.285	9.336	EPSD	COSMIC	7.780	Gain
AGC_Akt_AKT1_ST	P18031	PTPN1	P31749	AKT1	T224	S222A	222	Missense	proximal	-2	no	9.882	9.430	EPSD	COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	P18031	PTPN1	P31749	AKT1	T224	C226F	226	Missense	proximal	2	no	9.882	10.130	EPSD	COSMIC	7.780	Up-regulation
AGC_Akt_AKT1_ST	P18031	PTPN1	P31749	AKT1	S243	K248T	248	Missense	distal	5	no	9.744	9.742	EPSD	COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	P18031	PTPN1	P31749	AKT1	S352	E349K	349	Missense	distal	-3	no	5.944	7.995	EPSD	COSMIC	7.780	Gain
AGC_Akt_AKT1_ST	P18031	PTPN1	P31749	AKT1	T368	S365R	365	Missense	distal	-3	no	1.251	9.027	EPSD	COSMIC	7.780	Gain
AGC_Akt_AKT1_ST	P18031	PTPN1	P31749	AKT1	S378	G377R	377	Missense	proximal	-1	no	8.454	8.493	EPSD	COSMIC	7.780	Up-regulation
AGC_Akt_AKT1_ST	P18031	PTPN1	P31749	AKT1	S378	R373Q	373	Missense	distal	-5	no	8.454	4.226	EPSD	COSMIC	7.780	Loss
AGC_Akt_AKT1_ST	P18031	PTPN1	P31749	AKT1	S378	A385S	385	Missense	distal	7	no	8.454	8.504	EPSD	COSMIC	7.780	Up-regulation
AGC_Akt_AKT1_ST	P18031	PTPN1	P31749	AKT1	S378	A385V	385	Missense	distal	7	no	8.454	8.449	EPSD	COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	P18031	PTPN1	P31749	AKT1	S378	R373L	373	Missense	distal	-5	no	8.454	4.327	EPSD	COSMIC	7.780	Loss
AGC_Akt_AKT1_ST	P18031	PTPN1	P31749	AKT1	S378	S372I	372	Missense	distal	-6	no	8.454	8.333	EPSD	COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	P68400	CSNK2A1	P31749	AKT1	T13	R19T	19	Missense	distal	6	no	15.151	15.173	PhosphoSitePlus	COSMIC	7.780	Up-regulation
AGC_Akt_AKT1_ST	P68400	CSNK2A1	P31749	AKT1	S194	S194F	194	Missense	central	0	yes	10.046	0.000	EPSD	COSMIC	7.780	Loss
AGC_Akt_AKT1_ST	Q96HP0	DOCK6	P31749	AKT1	S30	P33L	33	Missense	distal	3	no	13.110	13.094	EPSD	COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	Q96HP0	DOCK6	P31749	AKT1	S30	Q24H	24	Missense	distal	-6	no	13.110	13.075	EPSD	COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	Q96HP0	DOCK6	P31749	AKT1	S40	P33L	33	Missense	distal	-7	no	12.727	12.688	EPSD	COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	Q96HP0	DOCK6	P31749	AKT1	S439	A443T	443	Missense	distal	4	no	9.361	9.231	EPSD	COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	Q96HP0	DOCK6	P31749	AKT1	S439	D441E	441	Missense	proximal	2	no	9.361	9.771	EPSD	COSMIC	7.780	Up-regulation
AGC_Akt_AKT1_ST	Q96HP0	DOCK6	P31749	AKT1	S483	R481C	481	Missense	proximal	-2	no	12.700	11.236	EPSD	COSMIC;CCLE	7.780	Down-regulation
AGC_Akt_AKT1_ST	Q96HP0	DOCK6	P31749	AKT1	S483	R488Q	488	Missense	distal	5	no	12.700	12.649	EPSD	COSMIC;CCLE	7.780	Down-regulation
AGC_Akt_AKT1_ST	Q96HP0	DOCK6	P31749	AKT1	S484	R481C	481	Missense	distal	-3	no	11.184	5.011	EPSD	COSMIC;CCLE	7.780	Loss
AGC_Akt_AKT1_ST	Q96HP0	DOCK6	P31749	AKT1	S484	P491L	491	Missense	distal	7	no	11.184	11.176	EPSD	COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	Q96HP0	DOCK6	P31749	AKT1	S484	R488Q	488	Missense	distal	4	no	11.184	11.307	EPSD	COSMIC;CCLE	7.780	Up-regulation
AGC_Akt_AKT1_ST	Q96HP0	DOCK6	P31749	AKT1	T493	P491L	491	Missense	proximal	-2	no	14.032	14.000	EPSD	COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	Q96HP0	DOCK6	P31749	AKT1	T493	R488Q	488	Missense	distal	-5	no	14.032	9.805	EPSD	COSMIC;CCLE	7.780	Down-regulation
AGC_Akt_AKT1_ST	Q96HP0	DOCK6	P31749	AKT1	S872	R869S	869	Missense	distal	-3	no	11.378	3.601	EPSD	COSMIC	7.780	Loss
AGC_Akt_AKT1_ST	Q96HP0	DOCK6	P31749	AKT1	S1073	S1071F	1071	Missense	proximal	-2	no	8.260	7.393	EPSD	COSMIC	7.780	Loss
AGC_Akt_AKT1_ST	Q96HP0	DOCK6	P31749	AKT1	S1073	T1078I	1078	Missense	distal	5	no	8.260	8.163	EPSD	COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	Q96HP0	DOCK6	P31749	AKT1	S1073	P1072R	1072	Missense	proximal	-1	no	8.260	8.300	EPSD	COSMIC	7.780	Up-regulation
AGC_Akt_AKT1_ST	Q96HP0	DOCK6	P31749	AKT1	S1075	P1072R	1072	Missense	distal	-3	no	6.941	13.581	EPSD	COSMIC	7.780	Gain
AGC_Akt_AKT1_ST	Q96HP0	DOCK6	P31749	AKT1	T1077	P1072R	1072	Missense	distal	-5	no	4.950	8.960	EPSD	COSMIC	7.780	Gain
AGC_Akt_AKT1_ST	Q96HP0	DOCK6	P31749	AKT1	S1194	G1187S	1187	Missense	distal	-7	no	15.967	16.153	PhosphoSitePlus	COSMIC	7.780	Up-regulation
AGC_Akt_AKT1_ST	Q96HP0	DOCK6	P31749	AKT1	S1343	R1340C	1340	Missense	distal	-3	no	14.730	8.556	EPSD	COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	Q96HP0	DOCK6	P31749	AKT1	S2036	A2040S	2040	Missense	distal	4	no	7.860	7.736	EPSD	COSMIC	7.780	Loss
AGC_Akt_AKT1_ST	Q96HP0	DOCK6	P31749	AKT1	S2036	R2039T	2039	Missense	distal	3	no	7.860	7.876	EPSD	COSMIC	7.780	Up-regulation
AGC_Akt_AKT1_ST	P62424	RPL7A	P31749	AKT1	T106	R113S	113	Missense	distal	7	no	12.130	12.123	PhosphoSitePlus	COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	P62424	RPL7A	P31749	AKT1	T200	A203T	203	Missense	distal	3	no	8.949	9.006	EPSD	COSMIC	7.780	Up-regulation
AGC_Akt_AKT1_ST	P22736	NR4A1	P31749	AKT1	S23	R18C	18	Missense	distal	-5	no	9.619	5.542	EPSD	COSMIC	7.780	Loss
AGC_Akt_AKT1_ST	P22736	NR4A1	P31749	AKT1	T174	E168K	168	Missense	distal	-6	no	9.744	9.811	EPSD	COSMIC	7.780	Up-regulation
AGC_Akt_AKT1_ST	P22736	NR4A1	P31749	AKT1	S201	P198R	198	Missense	distal	-3	no	6.280	12.920	EPSD	COSMIC;GDSC;CCLE	7.780	Gain
AGC_Akt_AKT1_ST	P22736	NR4A1	P31749	AKT1	S341	G344R	344	Missense	distal	3	no	12.553	12.628	EPSD	COSMIC	7.780	Up-regulation
AGC_Akt_AKT1_ST	P22736	NR4A1	P31749	AKT1	S341	R348W	348	Missense	distal	7	no	12.553	12.455	EPSD	COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	P22736	NR4A1	P31749	AKT1	S341	R345Q	345	Missense	distal	4	no	12.553	12.676	EPSD	COSMIC	7.780	Up-regulation
AGC_Akt_AKT1_ST	P22736	NR4A1	P31749	AKT1	S341	R338L	338	Missense	distal	-3	no	12.553	5.559	EPSD	COSMIC	7.780	Loss
AGC_Akt_AKT1_ST	P22736	NR4A1	P31749	AKT1	S341	R338Q	338	Missense	distal	-3	no	12.553	5.342	EPSD	COSMIC	7.780	Loss
AGC_Akt_AKT1_ST	P22736	NR4A1	P31749	AKT1	S351	G344R	344	Missense	distal	-7	no	14.750	14.992	PhosphoSitePlus	COSMIC	7.780	Up-regulation
AGC_Akt_AKT1_ST	P22736	NR4A1	P31749	AKT1	S351	R348W	348	Missense	distal	-3	no	14.750	5.809	PhosphoSitePlus	COSMIC	7.780	Loss
AGC_Akt_AKT1_ST	P22736	NR4A1	P31749	AKT1	S351	P350S	350	Missense	proximal	-1	no	14.750	14.779	PhosphoSitePlus	COSMIC	7.780	Up-regulation
AGC_Akt_AKT1_ST	P22736	NR4A1	P31749	AKT1	S351	R345Q	345	Missense	distal	-6	no	14.750	14.666	PhosphoSitePlus	COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	P22736	NR4A1	P31749	AKT1	S351	P353L	353	Missense	proximal	2	no	14.750	14.541	PhosphoSitePlus	COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	P22736	NR4A1	P31749	AKT1	S351	P357L	357	Missense	distal	6	no	14.750	14.740	PhosphoSitePlus	COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	P42858	HTT	P31749	AKT1	S417	R416H	416	Missense	proximal	-1	no	11.391	11.347	EPSD	COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	P42858	HTT	P31749	AKT1	S419	R416H	416	Missense	distal	-3	no	17.050	12.351	PhosphoSitePlus	COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	P42858	HTT	P31749	AKT1	S463	V461A	461	Missense	proximal	-2	no	9.890	10.628	EPSD	COSMIC	7.780	Up-regulation
AGC_Akt_AKT1_ST	P42858	HTT	P31749	AKT1	S463	R458T	458	Missense	distal	-5	no	9.890	6.160	EPSD	COSMIC;GDSC;CCLE	7.780	Loss
AGC_Akt_AKT1_ST	P42858	HTT	P31749	AKT1	S620	E615K	615	Missense	distal	-5	no	6.565	8.263	EPSD	COSMIC	7.780	Gain
AGC_Akt_AKT1_ST	P42858	HTT	P31749	AKT1	S621	E615K	615	Missense	distal	-6	no	11.834	11.900	EPSD	COSMIC	7.780	Up-regulation
AGC_Akt_AKT1_ST	P42858	HTT	P31749	AKT1	S640	M633T	633	Missense	distal	-7	no	12.805	13.072	EPSD	COSMIC	7.780	Up-regulation
AGC_Akt_AKT1_ST	P42858	HTT	P31749	AKT1	S1111	L1105P	1105	Missense	distal	-6	no	9.187	9.174	EPSD	COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	P42858	HTT	P31749	AKT1	S1111	P1117S	1117	Missense	distal	6	no	9.187	9.280	EPSD	COSMIC	7.780	Up-regulation
AGC_Akt_AKT1_ST	P42858	HTT	P31749	AKT1	S1111	A1115G	1115	Missense	distal	4	no	9.187	9.236	EPSD	COSMIC	7.780	Up-regulation
AGC_Akt_AKT1_ST	P42858	HTT	P31749	AKT1	S1349	Y1355H	1355	Missense	distal	6	no	8.613	8.581	EPSD	COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	P42858	HTT	P31749	AKT1	S1862	S1862N	1862	Missense	central	0	yes	8.434	0.000	EPSD	COSMIC	7.780	Loss
AGC_Akt_AKT1_ST	P42858	HTT	P31749	AKT1	S1864	S1862N	1862	Missense	proximal	-2	no	11.103	10.417	EPSD	COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	P42858	HTT	P31749	AKT1	S1865	S1862N	1862	Missense	distal	-3	no	8.516	8.815	EPSD	COSMIC	7.780	Up-regulation
AGC_Akt_AKT1_ST	P42858	HTT	P31749	AKT1	S2114	G2119C	2119	Missense	distal	5	no	12.204	12.149	EPSD	COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	P42858	HTT	P31749	AKT1	T2455	G2457S	2457	Missense	proximal	2	no	8.834	9.166	EPSD	COSMIC	7.780	Up-regulation
AGC_Akt_AKT1_ST	P42858	HTT	P31749	AKT1	T2455	I2450V	2450	Missense	distal	-5	no	8.834	9.087	EPSD	COSMIC	7.780	Up-regulation
AGC_Akt_AKT1_ST	P42858	HTT	P31749	AKT1	T2455	S2460N	2460	Missense	distal	5	no	8.834	8.800	EPSD	COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	P42858	HTT	P31749	AKT1	S2548	R2542K	2542	Missense	distal	-6	no	11.391	11.377	EPSD	COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	P05787	KRT8	P31749	AKT1	S9	S9F	9	Missense	central	0	yes	8.946	0.000	EPSD	COSMIC	7.780	Loss
AGC_Akt_AKT1_ST	P05787	KRT8	P31749	AKT1	S13	S9F	9	Missense	distal	-4	no	9.637	8.469	EPSD	COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	P05787	KRT8	P31749	AKT1	T26	S31A	31	Missense	distal	5	no	12.661	12.610	EPSD	COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	P05787	KRT8	P31749	AKT1	T26	S31Y	31	Missense	distal	5	no	12.661	12.618	EPSD	COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	P05787	KRT8	P31749	AKT1	S35	S31A	31	Missense	distal	-4	no	12.612	11.890	EPSD	COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	P05787	KRT8	P31749	AKT1	S35	S36L	36	Missense	proximal	1	no	12.612	12.711	EPSD	COSMIC	7.780	Up-regulation
AGC_Akt_AKT1_ST	P05787	KRT8	P31749	AKT1	S35	S31Y	31	Missense	distal	-4	no	12.612	11.753	EPSD	COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	P05787	KRT8	P31749	AKT1	S35	S35F	35	Missense	central	0	yes	12.612	0.000	EPSD	COSMIC	7.780	Loss
AGC_Akt_AKT1_ST	P05787	KRT8	P31749	AKT1	S37	S43F	43	Missense	distal	6	no	8.163	8.044	EPSD	COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	P05787	KRT8	P31749	AKT1	S37	S31A	31	Missense	distal	-6	no	8.163	8.108	EPSD	COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	P05787	KRT8	P31749	AKT1	S37	S36L	36	Missense	proximal	-1	no	8.163	8.135	EPSD	COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	P05787	KRT8	P31749	AKT1	S37	S43I	43	Missense	distal	6	no	8.163	7.999	EPSD	COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	P05787	KRT8	P31749	AKT1	S37	S43R	43	Missense	distal	6	no	8.163	8.162	EPSD	COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	P05787	KRT8	P31749	AKT1	S37	S31Y	31	Missense	distal	-6	no	8.163	8.104	EPSD	COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	P05787	KRT8	P31749	AKT1	S37	S35F	35	Missense	proximal	-2	no	8.163	7.297	EPSD	COSMIC	7.780	Loss
AGC_Akt_AKT1_ST	P05787	KRT8	P31749	AKT1	S43	S43F	43	Missense	central	0	yes	11.867	0.000	EPSD	COSMIC	7.780	Loss
AGC_Akt_AKT1_ST	P05787	KRT8	P31749	AKT1	S43	S36L	36	Missense	distal	-7	no	11.867	11.633	EPSD	COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	P05787	KRT8	P31749	AKT1	S43	S43I	43	Missense	central	0	yes	11.867	0.000	EPSD	COSMIC	7.780	Loss
AGC_Akt_AKT1_ST	P05787	KRT8	P31749	AKT1	S43	S43R	43	Missense	central	0	yes	11.867	0.000	EPSD	COSMIC	7.780	Loss
AGC_Akt_AKT1_ST	P05787	KRT8	P31749	AKT1	S74	S71R	71	Missense	distal	-3	no	2.232	10.009	EPSD	COSMIC	7.780	Gain
AGC_Akt_AKT1_ST	P05787	KRT8	P31749	AKT1	S280	R273C	273	Missense	distal	-7	no	9.529	9.050	EPSD	COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	P05787	KRT8	P31749	AKT1	T305	R301C	301	Missense	distal	-4	no	12.294	10.615	EPSD	COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	P05787	KRT8	P31749	AKT1	T305	M310I	310	Missense	distal	5	no	12.294	12.254	EPSD	COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	P05787	KRT8	P31749	AKT1	T305	R302H	302	Missense	distal	-3	no	12.294	7.595	EPSD	COSMIC	7.780	Loss
AGC_Akt_AKT1_ST	P05787	KRT8	P31749	AKT1	T305	E306G	306	Missense	proximal	1	no	12.294	12.084	EPSD	COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	P05787	KRT8	P31749	AKT1	T305	R302C	302	Missense	distal	-3	no	12.294	6.120	EPSD	COSMIC;GDSC	7.780	Loss
AGC_Akt_AKT1_ST	P05787	KRT8	P31749	AKT1	T305	R301Q	301	Missense	distal	-4	no	12.294	11.672	EPSD	COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	P05787	KRT8	P31749	AKT1	S315	M310I	310	Missense	distal	-5	no	10.926	10.881	EPSD	COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	P05787	KRT8	P31749	AKT1	S315	R316Q	316	Missense	proximal	1	no	10.926	10.631	EPSD	COSMIC;GDSC;CCLE	7.780	Down-regulation
AGC_Akt_AKT1_ST	P05787	KRT8	P31749	AKT1	S315	R316W	316	Missense	proximal	1	no	10.926	10.634	EPSD	COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	P05787	KRT8	P31749	AKT1	S404	E398K	398	Missense	distal	-6	no	11.574	11.640	EPSD	COSMIC	7.780	Up-regulation
AGC_Akt_AKT1_ST	P05787	KRT8	P31749	AKT1	S404	G405A	405	Missense	proximal	1	no	11.574	11.805	EPSD	COSMIC	7.780	Up-regulation
AGC_Akt_AKT1_ST	P05787	KRT8	P31749	AKT1	S404	E403K	403	Missense	proximal	-1	no	11.574	11.595	EPSD	COSMIC	7.780	Up-regulation
AGC_Akt_AKT1_ST	P05787	KRT8	P31749	AKT1	S457	R459M	459	Missense	proximal	2	no	13.915	13.670	EPSD	COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	P05787	KRT8	P31749	AKT1	S457	S458F	458	Missense	proximal	1	no	13.915	13.932	EPSD	COSMIC	7.780	Up-regulation
AGC_Akt_AKT1_ST	P05787	KRT8	P31749	AKT1	S457	S458T	458	Missense	proximal	1	no	13.915	14.108	EPSD	COSMIC	7.780	Up-regulation
AGC_Akt_AKT1_ST	P05787	KRT8	P31749	AKT1	S457	R454G	454	Missense	distal	-3	no	13.915	7.159	EPSD	COSMIC	7.780	Loss
AGC_Akt_AKT1_ST	P05787	KRT8	P31749	AKT1	S458	R459M	459	Missense	proximal	1	no	7.870	7.662	EPSD	COSMIC	7.780	Loss
AGC_Akt_AKT1_ST	P05787	KRT8	P31749	AKT1	S458	S458F	458	Missense	central	0	yes	7.870	0.000	EPSD	COSMIC	7.780	Loss
AGC_Akt_AKT1_ST	P05787	KRT8	P31749	AKT1	S458	R454G	454	Missense	distal	-4	no	7.870	7.055	EPSD	COSMIC	7.780	Loss
AGC_Akt_AKT1_ST	P05787	KRT8	P31749	AKT1	S475	S477F	477	Missense	proximal	2	no	9.810	9.233	EPSD	COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	P05787	KRT8	P31749	AKT1	S475	S478C	478	Missense	distal	3	no	9.810	9.633	EPSD	COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	P40818	USP8	P31749	AKT1	S14	L11F	11	Missense	distal	-3	no	8.128	9.528	EPSD	COSMIC	7.780	Up-regulation
AGC_Akt_AKT1_ST	P40818	USP8	P31749	AKT1	S32	S35R	35	Missense	distal	3	no	8.807	8.790	EPSD	COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	P40818	USP8	P31749	AKT1	S425	K424Q	424	Missense	proximal	-1	no	10.780	10.751	EPSD	COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	P40818	USP8	P31749	AKT1	S427	K424Q	424	Missense	distal	-3	no	11.043	8.352	EPSD	COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	P40818	USP8	P31749	AKT1	T577	P576T	576	Missense	proximal	-1	no	9.779	9.815	EPSD	COSMIC	7.780	Up-regulation
AGC_Akt_AKT1_ST	P40818	USP8	P31749	AKT1	T623	K630E	630	Missense	distal	7	no	10.471	10.437	EPSD	COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	P40818	USP8	P31749	AKT1	S641	T637S	637	Missense	distal	-4	no	11.629	11.573	EPSD	COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	P40818	USP8	P31749	AKT1	S641	E643D	643	Missense	proximal	2	no	11.629	11.219	EPSD	COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	P40818	USP8	P31749	AKT1	S711	S718P	718	Missense	distal	7	no	14.396	14.337	EPSD	COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	P40818	USP8	P31749	AKT1	S711	S718C	718	Missense	distal	7	no	14.396	14.273	EPSD	COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	P40818	USP8	P31749	AKT1	S711	S718F	718	Missense	distal	7	no	14.396	14.322	EPSD	COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	P40818	USP8	P31749	AKT1	S711	R715H	715	Missense	distal	4	no	14.396	14.580	EPSD	COSMIC	7.780	Up-regulation
AGC_Akt_AKT1_ST	P40818	USP8	P31749	AKT1	S711	Y717S	717	Missense	distal	6	no	14.396	14.484	EPSD	COSMIC	7.780	Up-regulation
AGC_Akt_AKT1_ST	P40818	USP8	P31749	AKT1	S711	S716Y	716	Missense	distal	5	no	14.396	14.352	EPSD	COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	P40818	USP8	P31749	AKT1	S711	Y717C	717	Missense	distal	6	no	14.396	14.281	EPSD	COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	P40818	USP8	P31749	AKT1	S711	L713R	713	Missense	proximal	2	no	14.396	14.769	EPSD	COSMIC	7.780	Up-regulation
AGC_Akt_AKT1_ST	P40818	USP8	P31749	AKT1	S716	L713R	713	Missense	distal	-3	no	3.856	10.850	EPSD	COSMIC	7.780	Gain
AGC_Akt_AKT1_ST	P40818	USP8	P31749	AKT1	S718	S718P	718	Missense	central	0	yes	11.474	0.000	PhosphoSitePlus	COSMIC	7.780	Loss
AGC_Akt_AKT1_ST	P40818	USP8	P31749	AKT1	S718	S718C	718	Missense	central	0	yes	11.474	0.000	PhosphoSitePlus	COSMIC	7.780	Loss
AGC_Akt_AKT1_ST	P40818	USP8	P31749	AKT1	S718	S718F	718	Missense	central	0	yes	11.474	0.000	PhosphoSitePlus	COSMIC	7.780	Loss
AGC_Akt_AKT1_ST	P40818	USP8	P31749	AKT1	S718	S719P	719	Missense	proximal	1	no	11.474	11.319	PhosphoSitePlus	COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	P40818	USP8	P31749	AKT1	S718	A725T	725	Missense	distal	7	no	11.474	11.535	PhosphoSitePlus	COSMIC	7.780	Up-regulation
AGC_Akt_AKT1_ST	P40818	USP8	P31749	AKT1	S718	D721N	721	Missense	distal	3	no	11.474	11.529	PhosphoSitePlus	COSMIC	7.780	Up-regulation
AGC_Akt_AKT1_ST	P40818	USP8	P31749	AKT1	S718	R715H	715	Missense	distal	-3	no	11.474	6.775	PhosphoSitePlus	COSMIC	7.780	Loss
AGC_Akt_AKT1_ST	P40818	USP8	P31749	AKT1	S718	Y717S	717	Missense	proximal	-1	no	11.474	11.500	PhosphoSitePlus	COSMIC	7.780	Up-regulation
AGC_Akt_AKT1_ST	P40818	USP8	P31749	AKT1	S718	S716Y	716	Missense	proximal	-2	no	11.474	10.552	PhosphoSitePlus	COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	P40818	USP8	P31749	AKT1	S718	P720L	720	Missense	proximal	2	no	11.474	11.265	PhosphoSitePlus	COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	P40818	USP8	P31749	AKT1	S718	Y717C	717	Missense	proximal	-1	no	11.474	11.440	PhosphoSitePlus	COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	P40818	USP8	P31749	AKT1	S718	L713R	713	Missense	distal	-5	no	11.474	15.600	PhosphoSitePlus	COSMIC	7.780	Up-regulation
AGC_Akt_AKT1_ST	P40818	USP8	P31749	AKT1	T735	T735A	735	Missense	central	0	yes	11.383	0.000	EPSD	COSMIC	7.780	Loss
AGC_Akt_AKT1_ST	P40818	USP8	P31749	AKT1	T735	V736I	736	Missense	proximal	1	no	11.383	11.136	EPSD	COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	P40818	USP8	P31749	AKT1	T735	T735I	735	Missense	central	0	yes	11.383	0.000	EPSD	COSMIC	7.780	Loss
AGC_Akt_AKT1_ST	P40818	USP8	P31749	AKT1	T735	K731N	731	Missense	distal	-4	no	11.383	10.744	EPSD	COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	P40818	USP8	P31749	AKT1	T737	T735A	735	Missense	proximal	-2	no	9.216	8.830	EPSD	COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	P40818	USP8	P31749	AKT1	T737	V736I	736	Missense	proximal	-1	no	9.216	9.201	EPSD	COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	P40818	USP8	P31749	AKT1	T737	N744S	744	Missense	distal	7	no	9.216	9.251	EPSD	COSMIC	7.780	Up-regulation
AGC_Akt_AKT1_ST	P40818	USP8	P31749	AKT1	T737	T735I	735	Missense	proximal	-2	no	9.216	8.041	EPSD	COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	P40818	USP8	P31749	AKT1	T737	K731N	731	Missense	distal	-6	no	9.216	9.149	EPSD	COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	P40818	USP8	P31749	AKT1	S972	E974G	974	Missense	proximal	2	no	11.301	11.158	EPSD	COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	P40818	USP8	P31749	AKT1	S972	T978I	978	Missense	distal	6	no	11.301	11.116	EPSD	COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	Q969H0	FBXW7	P31749	AKT1	S18	K11R	11	Missense	distal	-7	no	11.004	11.017	EPSD	COSMIC	7.780	Up-regulation
AGC_Akt_AKT1_ST	Q969H0	FBXW7	P31749	AKT1	S18	R13L	13	Missense	distal	-5	no	11.004	6.877	EPSD	COSMIC	7.780	Loss
AGC_Akt_AKT1_ST	Q969H0	FBXW7	P31749	AKT1	S227	R223L	223	Missense	distal	-4	no	15.464	14.254	PhosphoSitePlus	COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	Q969H0	FBXW7	P31749	AKT1	S227	P230L	230	Missense	distal	3	no	15.464	15.447	PhosphoSitePlus	COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	Q969H0	FBXW7	P31749	AKT1	S227	R223C	223	Missense	distal	-4	no	15.464	13.785	PhosphoSitePlus	COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	Q969H0	FBXW7	P31749	AKT1	S227	R222Q	222	Missense	distal	-5	no	15.464	11.236	PhosphoSitePlus	COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	Q969H0	FBXW7	P31749	AKT1	S227	L234M	234	Missense	distal	7	no	15.464	15.471	PhosphoSitePlus	COSMIC	7.780	Up-regulation
AGC_Akt_AKT1_ST	Q969H0	FBXW7	P31749	AKT1	S372	H379Y	379	Missense	distal	7	no	8.784	8.806	EPSD	COSMIC	7.780	Up-regulation
AGC_Akt_AKT1_ST	Q969H0	FBXW7	P31749	AKT1	S372	H379P	379	Missense	distal	7	no	8.784	8.790	EPSD	COSMIC	7.780	Up-regulation
AGC_Akt_AKT1_ST	Q969H0	FBXW7	P31749	AKT1	S372	R367P	367	Missense	distal	-5	no	8.784	4.774	EPSD	COSMIC	7.780	Loss
AGC_Akt_AKT1_ST	Q969H0	FBXW7	P31749	AKT1	S372	V375M	375	Missense	distal	3	no	8.784	8.789	EPSD	COSMIC	7.780	Up-regulation
AGC_Akt_AKT1_ST	Q969H0	FBXW7	P31749	AKT1	S372	H379R	379	Missense	distal	7	no	8.784	8.856	EPSD	COSMIC	7.780	Up-regulation
AGC_Akt_AKT1_ST	Q969H0	FBXW7	P31749	AKT1	S372	G378E	378	Missense	distal	6	no	8.784	8.830	EPSD	COSMIC	7.780	Up-regulation
AGC_Akt_AKT1_ST	Q969H0	FBXW7	P31749	AKT1	S372	P373L	373	Missense	proximal	1	no	8.784	9.038	EPSD	COSMIC	7.780	Up-regulation
AGC_Akt_AKT1_ST	Q969H0	FBXW7	P31749	AKT1	S372	E369G	369	Missense	distal	-3	no	8.784	8.600	EPSD	COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	Q969H0	FBXW7	P31749	AKT1	S372	R366S	366	Missense	distal	-6	no	8.784	8.750	EPSD	COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	Q969H0	FBXW7	P31749	AKT1	S372	R366T	366	Missense	distal	-6	no	8.784	8.781	EPSD	COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	Q969H0	FBXW7	P31749	AKT1	S372	L376S	376	Missense	distal	4	no	8.784	8.596	EPSD	COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	Q969H0	FBXW7	P31749	AKT1	S372	R366M	366	Missense	distal	-6	no	8.784	8.688	EPSD	COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	Q969H0	FBXW7	P31749	AKT1	T692	A685E	685	Missense	distal	-7	no	12.179	12.178	EPSD	COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	Q969H0	FBXW7	P31749	AKT1	T692	A685V	685	Missense	distal	-7	no	12.179	12.051	EPSD	COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	Q969H0	FBXW7	P31749	AKT1	T692	G687V	687	Missense	distal	-5	no	12.179	11.929	EPSD	COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	Q969H0	FBXW7	P31749	AKT1	T692	S688I	688	Missense	distal	-4	no	12.179	10.797	EPSD	COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	Q969H0	FBXW7	P31749	AKT1	T692	V686D	686	Missense	distal	-6	no	12.179	12.136	EPSD	COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	Q969H0	FBXW7	P31749	AKT1	T692	T692I	692	Missense	central	0	yes	12.179	0.000	EPSD	COSMIC	7.780	Loss
AGC_Akt_AKT1_ST	Q969H0	FBXW7	P31749	AKT1	T692	R689E	689	Missense	distal	-3	no	12.179	5.608	EPSD	COSMIC	7.780	Loss
AGC_Akt_AKT1_ST	Q969H0	FBXW7	P31749	AKT1	T692	V699L	699	Missense	distal	7	no	12.179	12.168	EPSD	COSMIC;GDSC;CCLE	7.780	Down-regulation
AGC_Akt_AKT1_ST	Q04912	MST1R	P31749	AKT1	S217	R220H	220	Missense	distal	3	no	11.885	11.801	EPSD	COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	Q04912	MST1R	P31749	AKT1	S217	R214H	214	Missense	distal	-3	no	11.885	7.186	EPSD	COSMIC	7.780	Loss
AGC_Akt_AKT1_ST	Q04912	MST1R	P31749	AKT1	S217	P213L	213	Missense	distal	-4	no	11.885	11.498	EPSD	COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	Q04912	MST1R	P31749	AKT1	S1056	D1063N	1063	Missense	distal	7	no	10.291	10.332	EPSD	COSMIC;GDSC;CCLE	7.780	Up-regulation
AGC_Akt_AKT1_ST	Q04912	MST1R	P31749	AKT1	S1056	K1054Q	1054	Missense	proximal	-2	no	10.291	9.339	EPSD	COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	Q04912	MST1R	P31749	AKT1	S1056	I1057M	1057	Missense	proximal	1	no	10.291	10.476	EPSD	COSMIC	7.780	Up-regulation
AGC_Akt_AKT1_ST	Q04912	MST1R	P31749	AKT1	S1056	R1053W	1053	Missense	distal	-3	no	10.291	1.350	EPSD	COSMIC	7.780	Loss
AGC_Akt_AKT1_ST	Q04912	MST1R	P31749	AKT1	S1394	R1389Q	1389	Missense	distal	-5	no	17.552	13.325	PhosphoSitePlus	COSMIC;GDSC	7.780	Down-regulation
AGC_Akt_AKT1_ST	Q04912	MST1R	P31749	AKT1	S1394	R1389W	1389	Missense	distal	-5	no	17.552	12.032	PhosphoSitePlus	COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	Q04912	MST1R	P31749	AKT1	S1394	R1391W	1391	Missense	distal	-3	no	17.552	8.612	PhosphoSitePlus	COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	Q04912	MST1R	P31749	AKT1	S1394	R1388C	1388	Missense	distal	-6	no	17.552	17.372	PhosphoSitePlus	COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	Q7Z589	EMSY	P31749	AKT1	S129	H126R	126	Missense	distal	-3	no	6.118	10.817	EPSD	COSMIC	7.780	Gain
AGC_Akt_AKT1_ST	Q7Z589	EMSY	P31749	AKT1	S173	P169S	169	Missense	distal	-4	no	9.940	10.676	EPSD	COSMIC	7.780	Up-regulation
AGC_Akt_AKT1_ST	Q7Z589	EMSY	P31749	AKT1	S173	A172T	172	Missense	proximal	-1	no	9.940	9.967	EPSD	COSMIC	7.780	Up-regulation
AGC_Akt_AKT1_ST	Q7Z589	EMSY	P31749	AKT1	S173	N177D	177	Missense	distal	4	no	9.940	10.055	EPSD	COSMIC	7.780	Up-regulation
AGC_Akt_AKT1_ST	Q7Z589	EMSY	P31749	AKT1	S173	R170S	170	Missense	distal	-3	no	9.940	2.164	EPSD	COSMIC	7.780	Loss
AGC_Akt_AKT1_ST	Q7Z589	EMSY	P31749	AKT1	S173	P171S	171	Missense	proximal	-2	no	9.940	10.764	EPSD	COSMIC	7.780	Up-regulation
AGC_Akt_AKT1_ST	Q7Z589	EMSY	P31749	AKT1	S173	V166I	166	Missense	distal	-7	no	9.940	9.845	EPSD	COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	Q7Z589	EMSY	P31749	AKT1	S173	P171L	171	Missense	proximal	-2	no	9.940	9.908	EPSD	COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	Q7Z589	EMSY	P31749	AKT1	S173	P174S	174	Missense	proximal	1	no	9.940	10.095	EPSD	COSMIC	7.780	Up-regulation
AGC_Akt_AKT1_ST	Q7Z589	EMSY	P31749	AKT1	S173	V180I	180	Missense	distal	7	no	9.940	9.898	EPSD	COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	Q7Z589	EMSY	P31749	AKT1	S173	S176C	176	Missense	distal	3	no	9.940	9.763	EPSD	COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	Q7Z589	EMSY	P31749	AKT1	S193	Y188H	188	Missense	distal	-5	no	6.460	7.973	EPSD	COSMIC	7.780	Gain
AGC_Akt_AKT1_ST	Q7Z589	EMSY	P31749	AKT1	T207	S211F	211	Missense	distal	4	no	14.849	15.045	EPSD	COSMIC	7.780	Up-regulation
AGC_Akt_AKT1_ST	Q7Z589	EMSY	P31749	AKT1	T207	S210F	210	Missense	distal	3	no	14.849	14.751	EPSD	COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	Q7Z589	EMSY	P31749	AKT1	T207	S212I	212	Missense	distal	5	no	14.849	14.752	EPSD	COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	Q7Z589	EMSY	P31749	AKT1	T207	S209F	209	Missense	proximal	2	no	14.849	14.272	EPSD	COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	Q7Z589	EMSY	P31749	AKT1	T207	S211I	211	Missense	distal	4	no	14.849	15.110	EPSD	COSMIC	7.780	Up-regulation
AGC_Akt_AKT1_ST	Q7Z589	EMSY	P31749	AKT1	T207	K203R	203	Missense	distal	-4	no	14.849	14.863	EPSD	COSMIC	7.780	Up-regulation
AGC_Akt_AKT1_ST	Q7Z589	EMSY	P31749	AKT1	T207	R206Q	206	Missense	proximal	-1	no	14.849	14.817	EPSD	COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	Q7Z589	EMSY	P31749	AKT1	T207	S213C	213	Missense	distal	6	no	14.849	14.646	EPSD	COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	Q7Z589	EMSY	P31749	AKT1	S209	S211F	211	Missense	proximal	2	no	17.159	16.582	PhosphoSitePlus	COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	Q7Z589	EMSY	P31749	AKT1	S209	S210F	210	Missense	proximal	1	no	17.159	17.177	PhosphoSitePlus	COSMIC	7.780	Up-regulation
AGC_Akt_AKT1_ST	Q7Z589	EMSY	P31749	AKT1	S209	S212I	212	Missense	distal	3	no	17.159	17.029	PhosphoSitePlus	COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	Q7Z589	EMSY	P31749	AKT1	S209	S209F	209	Missense	central	0	yes	17.159	0.000	PhosphoSitePlus	COSMIC	7.780	Loss
AGC_Akt_AKT1_ST	Q7Z589	EMSY	P31749	AKT1	S209	S211I	211	Missense	proximal	2	no	17.159	16.503	PhosphoSitePlus	COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	Q7Z589	EMSY	P31749	AKT1	S209	K203R	203	Missense	distal	-6	no	17.159	17.174	PhosphoSitePlus	COSMIC	7.780	Up-regulation
AGC_Akt_AKT1_ST	Q7Z589	EMSY	P31749	AKT1	S209	R206Q	206	Missense	distal	-3	no	17.159	9.948	PhosphoSitePlus	COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	Q7Z589	EMSY	P31749	AKT1	S209	S213C	213	Missense	distal	4	no	17.159	17.504	PhosphoSitePlus	COSMIC	7.780	Up-regulation
AGC_Akt_AKT1_ST	Q7Z589	EMSY	P31749	AKT1	S210	S211F	211	Missense	proximal	1	no	10.213	10.231	EPSD	COSMIC	7.780	Up-regulation
AGC_Akt_AKT1_ST	Q7Z589	EMSY	P31749	AKT1	S210	S210F	210	Missense	central	0	yes	10.213	0.000	EPSD	COSMIC	7.780	Loss
AGC_Akt_AKT1_ST	Q7Z589	EMSY	P31749	AKT1	S210	S212I	212	Missense	proximal	2	no	10.213	9.557	EPSD	COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	Q7Z589	EMSY	P31749	AKT1	S210	S209F	209	Missense	proximal	-1	no	10.213	10.178	EPSD	COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	Q7Z589	EMSY	P31749	AKT1	S210	S211I	211	Missense	proximal	1	no	10.213	9.964	EPSD	COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	Q7Z589	EMSY	P31749	AKT1	S210	K203R	203	Missense	distal	-7	no	10.213	10.226	EPSD	COSMIC	7.780	Up-regulation
AGC_Akt_AKT1_ST	Q7Z589	EMSY	P31749	AKT1	S210	R206Q	206	Missense	distal	-4	no	10.213	9.592	EPSD	COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	Q7Z589	EMSY	P31749	AKT1	S210	S213C	213	Missense	distal	3	no	10.213	10.036	EPSD	COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	Q7Z589	EMSY	P31749	AKT1	S211	S211F	211	Missense	central	0	yes	9.785	0.000	EPSD	COSMIC	7.780	Loss
AGC_Akt_AKT1_ST	Q7Z589	EMSY	P31749	AKT1	S211	S210F	210	Missense	proximal	-1	no	9.785	9.750	EPSD	COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	Q7Z589	EMSY	P31749	AKT1	S211	S212I	212	Missense	proximal	1	no	9.785	9.536	EPSD	COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	Q7Z589	EMSY	P31749	AKT1	S211	K218R	218	Missense	distal	7	no	9.785	9.792	EPSD	COSMIC	7.780	Up-regulation
AGC_Akt_AKT1_ST	Q7Z589	EMSY	P31749	AKT1	S211	S209F	209	Missense	proximal	-2	no	9.785	8.918	EPSD	COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	Q7Z589	EMSY	P31749	AKT1	S211	S211I	211	Missense	central	0	yes	9.785	0.000	EPSD	COSMIC	7.780	Loss
AGC_Akt_AKT1_ST	Q7Z589	EMSY	P31749	AKT1	S211	R206Q	206	Missense	distal	-5	no	9.785	5.557	EPSD	COSMIC	7.780	Loss
AGC_Akt_AKT1_ST	Q7Z589	EMSY	P31749	AKT1	S211	S213C	213	Missense	proximal	2	no	9.785	8.960	EPSD	COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	Q7Z589	EMSY	P31749	AKT1	S385	P386S	386	Missense	proximal	1	no	12.279	12.435	EPSD	COSMIC	7.780	Up-regulation
AGC_Akt_AKT1_ST	Q7Z589	EMSY	P31749	AKT1	S385	K387N	387	Missense	proximal	2	no	12.279	11.994	EPSD	COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	Q7Z589	EMSY	P31749	AKT1	S385	V390M	390	Missense	distal	5	no	12.279	12.282	EPSD	COSMIC	7.780	Up-regulation
AGC_Akt_AKT1_ST	Q7Z589	EMSY	P31749	AKT1	S385	A392S	392	Missense	distal	7	no	12.279	12.330	EPSD	COSMIC	7.780	Up-regulation
AGC_Akt_AKT1_ST	Q7Z589	EMSY	P31749	AKT1	S385	R382I	382	Missense	distal	-3	no	12.279	5.199	EPSD	COSMIC	7.780	Loss
AGC_Akt_AKT1_ST	Q7Z589	EMSY	P31749	AKT1	S385	M378V	378	Missense	distal	-7	no	12.279	12.218	EPSD	COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	Q7Z589	EMSY	P31749	AKT1	S407	K402N	402	Missense	distal	-5	no	9.121	7.033	EPSD	COSMIC	7.780	Loss
AGC_Akt_AKT1_ST	Q7Z589	EMSY	P31749	AKT1	S407	P401S	401	Missense	distal	-6	no	9.121	9.185	EPSD	COSMIC	7.780	Up-regulation
AGC_Akt_AKT1_ST	Q7Z589	EMSY	P31749	AKT1	S407	Y413C	413	Missense	distal	6	no	9.121	9.006	EPSD	COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	Q7Z589	EMSY	P31749	AKT1	S407	Q410R	410	Missense	distal	3	no	9.121	9.177	EPSD	COSMIC;GDSC	7.780	Up-regulation
AGC_Akt_AKT1_ST	Q7Z589	EMSY	P31749	AKT1	S407	Q411R	411	Missense	distal	4	no	9.121	8.997	EPSD	COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	Q7Z589	EMSY	P31749	AKT1	S538	I539M	539	Missense	proximal	1	no	8.113	8.299	EPSD	COSMIC	7.780	Up-regulation
AGC_Akt_AKT1_ST	Q7Z589	EMSY	P31749	AKT1	S538	I540M	540	Missense	proximal	2	no	8.113	8.353	EPSD	COSMIC	7.780	Up-regulation
AGC_Akt_AKT1_ST	Q7Z589	EMSY	P31749	AKT1	S793	K788N	788	Missense	distal	-5	no	9.791	7.704	EPSD	COSMIC	7.780	Loss
AGC_Akt_AKT1_ST	Q7Z589	EMSY	P31749	AKT1	S793	E792G	792	Missense	proximal	-1	no	9.791	9.776	EPSD	COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	Q7Z589	EMSY	P31749	AKT1	S793	R796G	796	Missense	distal	3	no	9.791	9.717	EPSD	COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	Q7Z589	EMSY	P31749	AKT1	S793	E792K	792	Missense	proximal	-1	no	9.791	9.812	EPSD	COSMIC	7.780	Up-regulation
AGC_Akt_AKT1_ST	Q7Z589	EMSY	P31749	AKT1	S793	Q797L	797	Missense	distal	4	no	9.791	9.845	EPSD	COSMIC	7.780	Up-regulation
AGC_Akt_AKT1_ST	Q7Z589	EMSY	P31749	AKT1	T799	E792G	792	Missense	distal	-7	no	10.433	10.397	EPSD	COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	Q7Z589	EMSY	P31749	AKT1	T799	R796G	796	Missense	distal	-3	no	10.433	3.677	EPSD	COSMIC	7.780	Loss
AGC_Akt_AKT1_ST	Q7Z589	EMSY	P31749	AKT1	T799	L802P	802	Missense	distal	3	no	10.433	10.449	EPSD	COSMIC	7.780	Up-regulation
AGC_Akt_AKT1_ST	Q7Z589	EMSY	P31749	AKT1	T799	A806T	806	Missense	distal	7	no	10.433	10.494	EPSD	COSMIC	7.780	Up-regulation
AGC_Akt_AKT1_ST	Q7Z589	EMSY	P31749	AKT1	T799	E792K	792	Missense	distal	-7	no	10.433	10.626	EPSD	COSMIC	7.780	Up-regulation
AGC_Akt_AKT1_ST	Q7Z589	EMSY	P31749	AKT1	T799	Q797L	797	Missense	proximal	-2	no	10.433	10.277	EPSD	COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	Q7Z589	EMSY	P31749	AKT1	S821	E814K	814	Missense	distal	-7	no	7.671	7.863	EPSD	COSMIC	7.780	Gain
AGC_Akt_AKT1_ST	Q7Z589	EMSY	P31749	AKT1	S1136	T1133R	1133	Missense	distal	-3	no	2.971	9.993	EPSD	COSMIC	7.780	Gain
AGC_Akt_AKT1_ST	Q7Z589	EMSY	P31749	AKT1	S1212	E1209K	1209	Missense	distal	-3	no	7.093	9.144	EPSD	COSMIC	7.780	Gain
AGC_Akt_AKT1_ST	Q7Z589	EMSY	P31749	AKT1	S1213	E1209K	1209	Missense	distal	-4	no	7.477	8.061	EPSD	COSMIC	7.780	Gain
AGC_Akt_AKT1_ST	P45880	VDAC2	P31749	AKT1	T7	I14T	14	Missense	distal	7	no	8.183	8.291	EPSD	COSMIC	7.780	Up-regulation
AGC_Akt_AKT1_ST	P45880	VDAC2	P31749	AKT1	T7	H4Q	4	Missense	distal	-3	no	8.183	5.671	EPSD	COSMIC	7.780	Loss
AGC_Akt_AKT1_ST	P63000	RAC1	P31749	AKT1	S71	L67I	67	Missense	distal	-4	no	13.601	13.344	PhosphoSitePlus	COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	P63000	RAC1	P31749	AKT1	S71	D65Y	65	Missense	distal	-6	no	13.601	13.661	PhosphoSitePlus	COSMIC	7.780	Up-regulation
AGC_Akt_AKT1_ST	P63000	RAC1	P31749	AKT1	S71	P69L	69	Missense	proximal	-2	no	13.601	13.569	PhosphoSitePlus	COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	P63000	RAC1	P31749	AKT1	S71	D65N	65	Missense	distal	-6	no	13.601	13.673	PhosphoSitePlus	COSMIC	7.780	Up-regulation
AGC_Akt_AKT1_ST	P63000	RAC1	P31749	AKT1	T125	I126M	126	Missense	proximal	1	no	8.880	9.066	EPSD	COSMIC	7.780	Up-regulation
AGC_Akt_AKT1_ST	P63000	RAC1	P31749	AKT1	T125	L119F	119	Missense	distal	-6	no	8.880	8.856	EPSD	COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	P63000	RAC1	P31749	AKT1	T125	D121N	121	Missense	distal	-4	no	8.880	9.601	EPSD	COSMIC	7.780	Up-regulation
AGC_Akt_AKT1_ST	Q15121	PEA15	P31749	AKT1	S90	R85L	85	Missense	distal	-5	no	9.680	5.554	EPSD	COSMIC	7.780	Loss
AGC_Akt_AKT1_ST	Q15121	PEA15	P31749	AKT1	S90	R85G	85	Missense	distal	-5	no	9.680	5.616	EPSD	COSMIC	7.780	Loss
AGC_Akt_AKT1_ST	Q15121	PEA15	P31749	AKT1	S104	K106N	106	Missense	proximal	2	no	12.656	12.371	EPSD	COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	Q15121	PEA15	P31749	AKT1	S116	I121M	121	Missense	distal	5	no	11.638	11.678	PhosphoSitePlus	COSMIC	7.780	Up-regulation
AGC_Akt_AKT1_ST	O96028	NSD2	P31749	AKT1	S56	L53F	53	Missense	distal	-3	no	6.948	8.348	EPSD	COSMIC	7.780	Gain
AGC_Akt_AKT1_ST	O96028	NSD2	P31749	AKT1	S102	G109W	109	Missense	distal	7	no	10.866	10.848	EPSD	COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	O96028	NSD2	P31749	AKT1	S102	E104K	104	Missense	proximal	2	no	10.866	11.071	EPSD	COSMIC	7.780	Up-regulation
AGC_Akt_AKT1_ST	O96028	NSD2	P31749	AKT1	S102	R99C	99	Missense	distal	-3	no	10.866	4.693	EPSD	COSMIC	7.780	Loss
AGC_Akt_AKT1_ST	O96028	NSD2	P31749	AKT1	S102	D95N	95	Missense	distal	-7	no	10.866	11.124	EPSD	COSMIC	7.780	Up-regulation
AGC_Akt_AKT1_ST	O96028	NSD2	P31749	AKT1	S121	K125N	125	Missense	distal	4	no	7.977	8.109	EPSD	COSMIC	7.780	Up-regulation
AGC_Akt_AKT1_ST	O96028	NSD2	P31749	AKT1	S172	S172N	172	Missense	central	0	yes	17.124	0.000	PhosphoSitePlus	COSMIC	7.780	Loss
AGC_Akt_AKT1_ST	O96028	NSD2	P31749	AKT1	S172	K170T	170	Missense	proximal	-2	no	17.124	16.807	PhosphoSitePlus	COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	O96028	NSD2	P31749	AKT1	S172	A165T	165	Missense	distal	-7	no	17.124	17.324	PhosphoSitePlus	COSMIC	7.780	Up-regulation
AGC_Akt_AKT1_ST	O96028	NSD2	P31749	AKT1	S172	A165V	165	Missense	distal	-7	no	17.124	16.996	PhosphoSitePlus	COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	O96028	NSD2	P31749	AKT1	S172	S177F	177	Missense	distal	5	no	17.124	17.052	PhosphoSitePlus	COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	O96028	NSD2	P31749	AKT1	S172	I173L	173	Missense	proximal	1	no	17.124	17.471	PhosphoSitePlus	COSMIC	7.780	Up-regulation
AGC_Akt_AKT1_ST	O96028	NSD2	P31749	AKT1	S172	S172C	172	Missense	central	0	yes	17.124	0.000	PhosphoSitePlus	COSMIC	7.780	Loss
AGC_Akt_AKT1_ST	O96028	NSD2	P31749	AKT1	S172	K174T	174	Missense	proximal	2	no	17.124	17.033	PhosphoSitePlus	COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	O96028	NSD2	P31749	AKT1	S407	R401W	401	Missense	distal	-6	no	11.153	11.006	EPSD	COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	O96028	NSD2	P31749	AKT1	S407	L405R	405	Missense	proximal	-2	no	11.153	11.822	EPSD	COSMIC	7.780	Up-regulation
AGC_Akt_AKT1_ST	O96028	NSD2	P31749	AKT1	S407	E410V	410	Missense	distal	3	no	11.153	11.105	EPSD	COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	O96028	NSD2	P31749	AKT1	S407	E413K	413	Missense	distal	6	no	11.153	11.223	EPSD	COSMIC	7.780	Up-regulation
AGC_Akt_AKT1_ST	O96028	NSD2	P31749	AKT1	S408	L405R	405	Missense	distal	-3	no	4.340	11.334	EPSD	COSMIC	7.780	Gain
AGC_Akt_AKT1_ST	O96028	NSD2	P31749	AKT1	T422	G419R	419	Missense	distal	-3	no	3.330	10.086	EPSD	COSMIC	7.780	Gain
AGC_Akt_AKT1_ST	O96028	NSD2	P31749	AKT1	S437	P439H	439	Missense	proximal	2	no	8.520	8.323	EPSD	COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	O96028	NSD2	P31749	AKT1	S437	P438S	438	Missense	proximal	1	no	8.520	8.675	EPSD	COSMIC	7.780	Up-regulation
AGC_Akt_AKT1_ST	O96028	NSD2	P31749	AKT1	S437	V435I	435	Missense	proximal	-2	no	8.520	8.469	EPSD	COSMIC;GDSC	7.780	Down-regulation
AGC_Akt_AKT1_ST	O96028	NSD2	P31749	AKT1	S437	R441M	441	Missense	distal	4	no	8.520	8.673	EPSD	COSMIC	7.780	Up-regulation
AGC_Akt_AKT1_ST	O96028	NSD2	P31749	AKT1	S437	R432K	432	Missense	distal	-5	no	8.520	6.123	EPSD	COSMIC	7.780	Loss
AGC_Akt_AKT1_ST	O96028	NSD2	P31749	AKT1	S437	G434R	434	Missense	distal	-3	no	8.520	15.276	EPSD	COSMIC	7.780	Up-regulation
AGC_Akt_AKT1_ST	O96028	NSD2	P31749	AKT1	S437	D430G	430	Missense	distal	-7	no	8.520	8.706	EPSD	COSMIC	7.780	Up-regulation
AGC_Akt_AKT1_ST	O96028	NSD2	P31749	AKT1	T444	P439H	439	Missense	distal	-5	no	12.047	12.962	EPSD	COSMIC	7.780	Up-regulation
AGC_Akt_AKT1_ST	O96028	NSD2	P31749	AKT1	T444	P438S	438	Missense	distal	-6	no	12.047	12.111	EPSD	COSMIC	7.780	Up-regulation
AGC_Akt_AKT1_ST	O96028	NSD2	P31749	AKT1	T444	R441M	441	Missense	distal	-3	no	12.047	4.541	EPSD	COSMIC	7.780	Loss
AGC_Akt_AKT1_ST	O96028	NSD2	P31749	AKT1	T445	P439H	439	Missense	distal	-6	no	8.245	8.225	EPSD	COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	O96028	NSD2	P31749	AKT1	T445	P438S	438	Missense	distal	-7	no	8.245	8.439	EPSD	COSMIC	7.780	Up-regulation
AGC_Akt_AKT1_ST	O96028	NSD2	P31749	AKT1	T445	R441M	441	Missense	distal	-4	no	8.245	7.250	EPSD	COSMIC	7.780	Loss
AGC_Akt_AKT1_ST	O96028	NSD2	P31749	AKT1	T551	D552G	552	Missense	proximal	1	no	14.693	14.601	EPSD	COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	O96028	NSD2	P31749	AKT1	T551	R557Q	557	Missense	distal	6	no	14.693	14.622	EPSD	COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	O96028	NSD2	P31749	AKT1	T551	D552E	552	Missense	proximal	1	no	14.693	14.810	EPSD	COSMIC	7.780	Up-regulation
AGC_Akt_AKT1_ST	O96028	NSD2	P31749	AKT1	T551	L556I	556	Missense	distal	5	no	14.693	14.663	EPSD	COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	O96028	NSD2	P31749	AKT1	S555	D552G	552	Missense	distal	-3	no	11.167	10.361	EPSD	COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	O96028	NSD2	P31749	AKT1	S555	R557Q	557	Missense	proximal	2	no	11.167	11.049	EPSD	COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	O96028	NSD2	P31749	AKT1	S555	D552E	552	Missense	distal	-3	no	11.167	10.546	EPSD	COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	O96028	NSD2	P31749	AKT1	S555	D560H	560	Missense	distal	5	no	11.167	11.175	EPSD	COSMIC;GDSC	7.780	Up-regulation
AGC_Akt_AKT1_ST	O96028	NSD2	P31749	AKT1	S555	L556I	556	Missense	proximal	1	no	11.167	10.819	EPSD	COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	O96028	NSD2	P31749	AKT1	S571	T566M	566	Missense	distal	-5	no	11.074	10.281	EPSD	COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	O96028	NSD2	P31749	AKT1	S571	K573E	573	Missense	proximal	2	no	11.074	10.869	EPSD	COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	O96028	NSD2	P31749	AKT1	S571	S571Y	571	Missense	central	0	yes	11.074	0.000	EPSD	COSMIC	7.780	Loss
AGC_Akt_AKT1_ST	O96028	NSD2	P31749	AKT1	S571	E576K	576	Missense	distal	5	no	11.074	11.108	EPSD	COSMIC	7.780	Up-regulation
AGC_Akt_AKT1_ST	O96028	NSD2	P31749	AKT1	S571	K565T	565	Missense	distal	-6	no	11.074	11.085	EPSD	COSMIC	7.780	Up-regulation
AGC_Akt_AKT1_ST	O96028	NSD2	P31749	AKT1	T605	R602W	602	Missense	distal	-3	no	14.319	5.379	EPSD	COSMIC	7.780	Loss
AGC_Akt_AKT1_ST	O96028	NSD2	P31749	AKT1	T605	A606T	606	Missense	proximal	1	no	14.319	14.586	EPSD	COSMIC	7.780	Up-regulation
AGC_Akt_AKT1_ST	O96028	NSD2	P31749	AKT1	T605	R602Q	602	Missense	distal	-3	no	14.319	7.108	EPSD	COSMIC	7.780	Loss
AGC_Akt_AKT1_ST	O96028	NSD2	P31749	AKT1	T605	R600Q	600	Missense	distal	-5	no	14.319	10.092	EPSD	COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	O96028	NSD2	P31749	AKT1	T605	R602L	602	Missense	distal	-3	no	14.319	7.325	EPSD	COSMIC	7.780	Loss
AGC_Akt_AKT1_ST	P04792	HSPB1	P31749	AKT1	S9	P14S	14	Missense	distal	5	no	10.774	10.827	EPSD	COSMIC	7.780	Up-regulation
AGC_Akt_AKT1_ST	P04792	HSPB1	P31749	AKT1	S9	F8L	8	Missense	proximal	-1	no	10.774	10.780	EPSD	COSMIC	7.780	Up-regulation
AGC_Akt_AKT1_ST	P04792	HSPB1	P31749	AKT1	S9	R5C	5	Missense	distal	-4	no	10.774	9.096	EPSD	COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	P04792	HSPB1	P31749	AKT1	S15	P14S	14	Missense	proximal	-1	no	10.969	10.998	EPSD	COSMIC	7.780	Up-regulation
AGC_Akt_AKT1_ST	P04792	HSPB1	P31749	AKT1	S15	R20W	20	Missense	distal	5	no	10.969	10.875	EPSD	COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	P04792	HSPB1	P31749	AKT1	S15	R20Q	20	Missense	distal	5	no	10.969	10.919	EPSD	COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	P04792	HSPB1	P31749	AKT1	S15	F8L	8	Missense	distal	-7	no	10.969	11.013	EPSD	COSMIC	7.780	Up-regulation
AGC_Akt_AKT1_ST	P04792	HSPB1	P31749	AKT1	S78	R75C	75	Missense	distal	-3	no	12.081	5.907	EPSD	COSMIC	7.780	Loss
AGC_Akt_AKT1_ST	P04792	HSPB1	P31749	AKT1	S82	R75C	75	Missense	distal	-7	no	12.296	11.817	PhosphoSitePlus	COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	P04792	HSPB1	P31749	AKT1	T139	R140Q	140	Missense	proximal	1	no	8.247	7.952	EPSD	COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	P04792	HSPB1	P31749	AKT1	T143	R140Q	140	Missense	distal	-3	no	13.469	6.258	EPSD	COSMIC	7.780	Loss
AGC_Akt_AKT1_ST	P53804	TTC3	P31749	AKT1	S759	L753V	753	Missense	distal	-6	no	8.002	7.977	EPSD	COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	P53804	TTC3	P31749	AKT1	S1915	T1918I	1918	Missense	distal	3	no	9.870	9.740	EPSD	COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	P56270	MAZ	P31749	AKT1	S222	K216N	216	Missense	distal	-6	no	10.247	10.180	EPSD	COSMIC;CCLE	7.780	Down-regulation
AGC_Akt_AKT1_ST	P56270	MAZ	P31749	AKT1	S222	S222L	222	Missense	central	0	yes	10.247	0.000	EPSD	COSMIC	7.780	Loss
AGC_Akt_AKT1_ST	P56270	MAZ	P31749	AKT1	S222	A215V	215	Missense	distal	-7	no	10.247	10.119	EPSD	COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	P56270	MAZ	P31749	AKT1	S300	S300L	300	Missense	central	0	yes	7.856	0.000	EPSD	COSMIC	7.780	Loss
AGC_Akt_AKT1_ST	P56270	MAZ	P31749	AKT1	S300	E304Q	304	Missense	distal	4	no	7.856	7.911	EPSD	COSMIC	7.780	Up-regulation
AGC_Akt_AKT1_ST	P56270	MAZ	P31749	AKT1	S323	D330A	330	Missense	distal	7	no	9.412	9.439	EPSD	COSMIC	7.780	Up-regulation
AGC_Akt_AKT1_ST	P09601	HMOX1	P31749	AKT1	S8	D7H	7	Missense	proximal	-1	no	9.807	9.820	EPSD	COSMIC	7.780	Up-regulation
AGC_Akt_AKT1_ST	P09601	HMOX1	P31749	AKT1	S8	L13F	13	Missense	distal	5	no	9.807	9.801	EPSD	COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	P09601	HMOX1	P31749	AKT1	S188	R185S	185	Missense	distal	-3	no	16.283	8.507	PhosphoSitePlus	COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	P09601	HMOX1	P31749	AKT1	S188	R185L	185	Missense	distal	-3	no	16.283	9.289	PhosphoSitePlus	COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	P09601	HMOX1	P31749	AKT1	S188	P193L	193	Missense	distal	5	no	16.283	16.269	PhosphoSitePlus	COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	Q13009	TIAM1	P31749	AKT1	T26	S20G	20	Missense	distal	-6	no	11.882	11.803	EPSD	COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	Q13009	TIAM1	P31749	AKT1	S33	R37W	37	Missense	distal	4	no	9.995	10.242	EPSD	COSMIC	7.780	Up-regulation
AGC_Akt_AKT1_ST	Q13009	TIAM1	P31749	AKT1	S33	R38K	38	Missense	distal	5	no	9.995	9.989	EPSD	COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	Q13009	TIAM1	P31749	AKT1	S33	R40H	40	Missense	distal	7	no	9.995	9.923	EPSD	COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	Q13009	TIAM1	P31749	AKT1	S43	V47G	47	Missense	distal	4	no	15.019	15.013	EPSD	COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	Q13009	TIAM1	P31749	AKT1	S43	I48T	48	Missense	distal	5	no	15.019	15.117	EPSD	COSMIC	7.780	Up-regulation
AGC_Akt_AKT1_ST	Q13009	TIAM1	P31749	AKT1	S43	R37W	37	Missense	distal	-6	no	15.019	14.872	EPSD	COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	Q13009	TIAM1	P31749	AKT1	S43	R38K	38	Missense	distal	-5	no	15.019	12.622	EPSD	COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	Q13009	TIAM1	P31749	AKT1	S43	R40H	40	Missense	distal	-3	no	15.019	10.321	EPSD	COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	Q13009	TIAM1	P31749	AKT1	S55	I48T	48	Missense	distal	-7	no	7.441	7.863	EPSD	COSMIC	7.780	Gain
AGC_Akt_AKT1_ST	Q13009	TIAM1	P31749	AKT1	S55	S52F	52	Missense	distal	-3	no	7.441	9.623	EPSD	COSMIC;GDSC;CCLE	7.780	Gain
AGC_Akt_AKT1_ST	Q13009	TIAM1	P31749	AKT1	S60	S58F	58	Missense	proximal	-2	no	13.091	12.224	EPSD	COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	Q13009	TIAM1	P31749	AKT1	S102	S102C	102	Missense	central	0	yes	9.939	0.000	EPSD	COSMIC	7.780	Loss
AGC_Akt_AKT1_ST	Q13009	TIAM1	P31749	AKT1	S102	S106T	106	Missense	distal	4	no	9.939	9.934	EPSD	COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	Q13009	TIAM1	P31749	AKT1	S102	S107P	107	Missense	distal	5	no	9.939	9.886	EPSD	COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	Q13009	TIAM1	P31749	AKT1	T104	S102C	102	Missense	proximal	-2	no	8.676	7.024	EPSD	COSMIC	7.780	Loss
AGC_Akt_AKT1_ST	Q13009	TIAM1	P31749	AKT1	T104	S106T	106	Missense	proximal	2	no	8.676	8.602	EPSD	COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	Q13009	TIAM1	P31749	AKT1	T104	S107P	107	Missense	distal	3	no	8.676	8.595	EPSD	COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	Q13009	TIAM1	P31749	AKT1	S170	S164C	164	Missense	distal	-6	no	9.616	9.470	EPSD	COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	Q13009	TIAM1	P31749	AKT1	S170	S164L	164	Missense	distal	-6	no	9.616	9.565	EPSD	COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	Q13009	TIAM1	P31749	AKT1	S224	R217L	217	Missense	distal	-7	no	9.607	9.318	EPSD	COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	Q13009	TIAM1	P31749	AKT1	T353	S350F	350	Missense	distal	-3	no	7.359	9.541	EPSD	COSMIC	7.780	Gain
AGC_Akt_AKT1_ST	Q13009	TIAM1	P31749	AKT1	S368	S372I	372	Missense	distal	4	no	7.702	7.963	EPSD	COSMIC	7.780	Gain
AGC_Akt_AKT1_ST	Q13009	TIAM1	P31749	AKT1	T679	V675A	675	Missense	distal	-4	no	9.345	9.717	EPSD	COSMIC	7.780	Up-regulation
AGC_Akt_AKT1_ST	Q13009	TIAM1	P31749	AKT1	S687	S687I	687	Missense	central	0	yes	11.534	0.000	EPSD	COSMIC	7.780	Loss
AGC_Akt_AKT1_ST	Q13009	TIAM1	P31749	AKT1	S694	S687I	687	Missense	distal	-7	no	8.523	8.150	EPSD	COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	Q13009	TIAM1	P31749	AKT1	S1036	A1030T	1030	Missense	distal	-6	no	8.483	8.569	EPSD	COSMIC	7.780	Up-regulation
AGC_Akt_AKT1_ST	Q13009	TIAM1	P31749	AKT1	S1036	A1030V	1030	Missense	distal	-6	no	8.483	8.462	EPSD	COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	Q13009	TIAM1	P31749	AKT1	S1036	D1037N	1037	Missense	proximal	1	no	8.483	8.607	EPSD	COSMIC	7.780	Up-regulation
AGC_Akt_AKT1_ST	Q13009	TIAM1	P31749	AKT1	S1036	Q1034H	1034	Missense	proximal	-2	no	8.483	8.134	EPSD	COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	Q13009	TIAM1	P31749	AKT1	S1143	R1138C	1138	Missense	distal	-5	no	9.376	5.299	EPSD	COSMIC	7.780	Loss
AGC_Akt_AKT1_ST	Q13009	TIAM1	P31749	AKT1	S1143	F1145S	1145	Missense	proximal	2	no	9.376	9.954	EPSD	COSMIC	7.780	Up-regulation
AGC_Akt_AKT1_ST	Q13009	TIAM1	P31749	AKT1	S1143	R1138H	1138	Missense	distal	-5	no	9.376	6.281	EPSD	COSMIC;GDSC;CCLE	7.780	Loss
AGC_Akt_AKT1_ST	Q13009	TIAM1	P31749	AKT1	S1143	T1150I	1150	Missense	distal	7	no	9.376	9.268	EPSD	COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	Q13009	TIAM1	P31749	AKT1	S1143	R1138P	1138	Missense	distal	-5	no	9.376	5.366	EPSD	COSMIC	7.780	Loss
AGC_Akt_AKT1_ST	Q13009	TIAM1	P31749	AKT1	S1143	A1144V	1144	Missense	proximal	1	no	9.376	9.449	EPSD	COSMIC	7.780	Up-regulation
AGC_Akt_AKT1_ST	Q13009	TIAM1	P31749	AKT1	S1143	S1148N	1148	Missense	distal	5	no	9.376	9.342	EPSD	COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	Q13009	TIAM1	P31749	AKT1	S1143	A1147S	1147	Missense	distal	4	no	9.376	9.252	EPSD	COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	Q13009	TIAM1	P31749	AKT1	S1321	H1318R	1318	Missense	distal	-3	no	6.931	11.629	EPSD	COSMIC	7.780	Gain
AGC_Akt_AKT1_ST	Q13009	TIAM1	P31749	AKT1	T1405	R1399I	1399	Missense	distal	-6	no	7.860	7.705	EPSD	COSMIC	7.780	Loss
AGC_Akt_AKT1_ST	Q13009	TIAM1	P31749	AKT1	T1405	L1408I	1408	Missense	distal	3	no	7.860	7.826	EPSD	COSMIC;CCLE	7.780	Down-regulation
AGC_Akt_AKT1_ST	Q13009	TIAM1	P31749	AKT1	T1405	H1398Y	1398	Missense	distal	-7	no	7.860	7.899	EPSD	COSMIC	7.780	Up-regulation
AGC_Akt_AKT1_ST	Q13009	TIAM1	P31749	AKT1	T1405	S1411F	1411	Missense	distal	6	no	7.860	7.740	EPSD	COSMIC	7.780	Loss
AGC_Akt_AKT1_ST	Q13009	TIAM1	P31749	AKT1	T1405	L1408R	1408	Missense	distal	3	no	7.860	7.941	EPSD	COSMIC	7.780	Up-regulation
AGC_Akt_AKT1_ST	Q13009	TIAM1	P31749	AKT1	S1411	L1408R	1408	Missense	distal	-3	no	5.007	12.001	EPSD	COSMIC	7.780	Gain
AGC_Akt_AKT1_ST	Q13009	TIAM1	P31749	AKT1	S1437	A1435E	1435	Missense	proximal	-2	no	12.334	12.378	EPSD	COSMIC	7.780	Up-regulation
AGC_Akt_AKT1_ST	Q13009	TIAM1	P31749	AKT1	S1437	G1444E	1444	Missense	distal	7	no	12.334	12.374	EPSD	COSMIC	7.780	Up-regulation
AGC_Akt_AKT1_ST	Q13009	TIAM1	P31749	AKT1	S1437	A1438S	1438	Missense	proximal	1	no	12.334	12.408	EPSD	COSMIC;CCLE	7.780	Up-regulation
AGC_Akt_AKT1_ST	Q13009	TIAM1	P31749	AKT1	S1532	S1534G	1534	Missense	proximal	2	no	8.334	8.002	EPSD	COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	Q13009	TIAM1	P31749	AKT1	S1532	R1527W	1527	Missense	distal	-5	no	8.334	2.815	EPSD	COSMIC	7.780	Loss
AGC_Akt_AKT1_ST	Q13009	TIAM1	P31749	AKT1	S1532	I1533M	1533	Missense	proximal	1	no	8.334	8.520	EPSD	COSMIC	7.780	Up-regulation
AGC_Akt_AKT1_ST	Q13009	TIAM1	P31749	AKT1	S1532	Q1525L	1525	Missense	distal	-7	no	8.334	8.239	EPSD	COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	Q13009	TIAM1	P31749	AKT1	S1532	R1536W	1536	Missense	distal	4	no	8.334	8.581	EPSD	COSMIC	7.780	Up-regulation
AGC_Akt_AKT1_ST	Q13009	TIAM1	P31749	AKT1	S1532	R1527Q	1527	Missense	distal	-5	no	8.334	4.107	EPSD	COSMIC	7.780	Loss
AGC_Akt_AKT1_ST	O15151	MDM4	P31749	AKT1	S20	S15R	15	Missense	distal	-5	no	6.902	11.372	EPSD	COSMIC	7.780	Gain
AGC_Akt_AKT1_ST	O15151	MDM4	P31749	AKT1	T150	S144L	144	Missense	distal	-6	no	13.761	13.710	EPSD	COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	O15151	MDM4	P31749	AKT1	T150	P156H	156	Missense	distal	6	no	13.761	13.733	EPSD	COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	O15151	MDM4	P31749	AKT1	T150	I155V	155	Missense	distal	5	no	13.761	13.798	EPSD	COSMIC	7.780	Up-regulation
AGC_Akt_AKT1_ST	O15151	MDM4	P31749	AKT1	T150	R147K	147	Missense	distal	-3	no	13.761	9.240	EPSD	COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	O15151	MDM4	P31749	AKT1	S291	V296I	296	Missense	distal	5	no	8.920	8.883	EPSD	COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	O15151	MDM4	P31749	AKT1	S291	L284P	284	Missense	distal	-7	no	8.920	8.960	EPSD	COSMIC	7.780	Up-regulation
AGC_Akt_AKT1_ST	O15151	MDM4	P31749	AKT1	S291	V298G	298	Missense	distal	7	no	8.920	8.902	EPSD	COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	O15151	MDM4	P31749	AKT1	S291	E297D	297	Missense	distal	6	no	8.920	8.830	EPSD	COSMIC;GDSC;CCLE	7.780	Down-regulation
AGC_Akt_AKT1_ST	O15151	MDM4	P31749	AKT1	S291	D286N	286	Missense	distal	-5	no	8.920	8.482	EPSD	COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	O15151	MDM4	P31749	AKT1	S291	S289F	289	Missense	proximal	-2	no	8.920	8.054	EPSD	COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	O15151	MDM4	P31749	AKT1	S342	L337V	337	Missense	distal	-5	no	9.130	8.942	EPSD	COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	O15151	MDM4	P31749	AKT1	S342	S342F	342	Missense	central	0	yes	9.130	0.000	EPSD	COSMIC	7.780	Loss
AGC_Akt_AKT1_ST	O15151	MDM4	P31749	AKT1	S344	L337V	337	Missense	distal	-7	no	8.555	8.511	EPSD	COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	O15151	MDM4	P31749	AKT1	S344	S342F	342	Missense	proximal	-2	no	8.555	7.688	EPSD	COSMIC	7.780	Loss
AGC_Akt_AKT1_ST	O15151	MDM4	P31749	AKT1	S367	S367L	367	Missense	central	0	yes	11.696	0.000	PhosphoSitePlus	COSMIC;GDSC;CCLE	7.780	Loss
AGC_Akt_AKT1_ST	O15151	MDM4	P31749	AKT1	S367	V370F	370	Missense	distal	3	no	11.696	11.687	PhosphoSitePlus	COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	O15151	MDM4	P31749	AKT1	S367	T365I	365	Missense	proximal	-2	no	11.696	10.521	PhosphoSitePlus	COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	O15151	MDM4	P31749	AKT1	S367	R364G	364	Missense	distal	-3	no	11.696	4.940	PhosphoSitePlus	COSMIC	7.780	Loss
AGC_Akt_AKT1_ST	Q7Z5H3	ARHGAP22	P31749	AKT1	S14	A9V	9	Missense	distal	-5	no	15.608	15.148	EPSD	COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	Q7Z5H3	ARHGAP22	P31749	AKT1	S14	R13C	13	Missense	proximal	-1	no	15.608	15.538	EPSD	COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	Q7Z5H3	ARHGAP22	P31749	AKT1	S16	A9V	9	Missense	distal	-7	no	18.130	18.002	PhosphoSitePlus	COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	Q7Z5H3	ARHGAP22	P31749	AKT1	S16	R13C	13	Missense	distal	-3	no	18.130	11.957	PhosphoSitePlus	COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	Q7Z5H3	ARHGAP22	P31749	AKT1	S346	T350M	350	Missense	distal	4	no	11.408	11.577	EPSD	COSMIC	7.780	Up-regulation
AGC_Akt_AKT1_ST	Q7Z5H3	ARHGAP22	P31749	AKT1	S346	K344R	344	Missense	proximal	-2	no	11.408	10.969	EPSD	COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	Q7Z5H3	ARHGAP22	P31749	AKT1	S346	A351T	351	Missense	distal	5	no	11.408	11.460	EPSD	COSMIC	7.780	Up-regulation
AGC_Akt_AKT1_ST	Q7Z5H3	ARHGAP22	P31749	AKT1	S346	R343W	343	Missense	distal	-3	no	11.408	2.468	EPSD	COSMIC	7.780	Loss
AGC_Akt_AKT1_ST	Q7Z5H3	ARHGAP22	P31749	AKT1	S346	R343Q	343	Missense	distal	-3	no	11.408	4.197	EPSD	COSMIC	7.780	Loss
AGC_Akt_AKT1_ST	Q7Z5H3	ARHGAP22	P31749	AKT1	S346	V340M	340	Missense	distal	-6	no	11.408	11.422	EPSD	COSMIC	7.780	Up-regulation
AGC_Akt_AKT1_ST	Q7Z5H3	ARHGAP22	P31749	AKT1	S359	G356R	356	Missense	distal	-3	no	5.324	12.080	EPSD	COSMIC	7.780	Gain
AGC_Akt_AKT1_ST	Q7Z5H3	ARHGAP22	P31749	AKT1	S395	V401M	401	Missense	distal	6	no	11.981	11.996	EPSD	COSMIC	7.780	Up-regulation
AGC_Akt_AKT1_ST	Q7Z5H3	ARHGAP22	P31749	AKT1	S395	A402T	402	Missense	distal	7	no	11.981	12.042	EPSD	COSMIC	7.780	Up-regulation
AGC_Akt_AKT1_ST	Q7Z5H3	ARHGAP22	P31749	AKT1	S417	S414R	414	Missense	distal	-3	no	3.761	11.537	EPSD	COSMIC;CCLE	7.780	Gain
AGC_Akt_AKT1_ST	Q7Z5H3	ARHGAP22	P31749	AKT1	S437	S430R	430	Missense	distal	-7	no	7.986	8.042	EPSD	COSMIC	7.780	Up-regulation
AGC_Akt_AKT1_ST	Q7Z5H3	ARHGAP22	P31749	AKT1	S437	S430F	430	Missense	distal	-7	no	7.986	7.708	EPSD	COSMIC	7.780	Loss
AGC_Akt_AKT1_ST	Q7Z5H3	ARHGAP22	P31749	AKT1	S437	R436L	436	Missense	proximal	-1	no	7.986	7.947	EPSD	COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	Q7Z5H3	ARHGAP22	P31749	AKT1	S437	G444R	444	Missense	distal	7	no	7.986	8.067	EPSD	COSMIC	7.780	Up-regulation
AGC_Akt_AKT1_ST	Q7Z5H3	ARHGAP22	P31749	AKT1	S437	R436H	436	Missense	proximal	-1	no	7.986	7.941	EPSD	COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	Q7Z5H3	ARHGAP22	P31749	AKT1	S437	R433Q	433	Missense	distal	-4	no	7.986	7.365	EPSD	COSMIC	7.780	Loss
AGC_Akt_AKT1_ST	Q7Z5H3	ARHGAP22	P31749	AKT1	S437	S437N	437	Missense	central	0	yes	7.986	0.000	EPSD	COSMIC	7.780	Loss
AGC_Akt_AKT1_ST	Q7Z5H3	ARHGAP22	P31749	AKT1	S437	S431L	431	Missense	distal	-6	no	7.986	7.935	EPSD	COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	Q7Z5H3	ARHGAP22	P31749	AKT1	S439	R436L	436	Missense	distal	-3	no	10.399	3.405	EPSD	COSMIC	7.780	Loss
AGC_Akt_AKT1_ST	Q7Z5H3	ARHGAP22	P31749	AKT1	S439	G444R	444	Missense	distal	5	no	10.399	10.469	EPSD	COSMIC	7.780	Up-regulation
AGC_Akt_AKT1_ST	Q7Z5H3	ARHGAP22	P31749	AKT1	S439	R436H	436	Missense	distal	-3	no	10.399	5.700	EPSD	COSMIC	7.780	Loss
AGC_Akt_AKT1_ST	Q7Z5H3	ARHGAP22	P31749	AKT1	S439	R433Q	433	Missense	distal	-6	no	10.399	10.315	EPSD	COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	Q7Z5H3	ARHGAP22	P31749	AKT1	S439	S437N	437	Missense	proximal	-2	no	10.399	9.713	EPSD	COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	Q7Z5H3	ARHGAP22	P31749	AKT1	S439	G446R	446	Missense	distal	7	no	10.399	10.480	EPSD	COSMIC	7.780	Up-regulation
AGC_Akt_AKT1_ST	Q7Z5H3	ARHGAP22	P31749	AKT1	S441	R436L	436	Missense	distal	-5	no	9.968	5.842	EPSD	COSMIC	7.780	Loss
AGC_Akt_AKT1_ST	Q7Z5H3	ARHGAP22	P31749	AKT1	S441	G444R	444	Missense	distal	3	no	9.968	10.042	EPSD	COSMIC	7.780	Up-regulation
AGC_Akt_AKT1_ST	Q7Z5H3	ARHGAP22	P31749	AKT1	S441	R436H	436	Missense	distal	-5	no	9.968	6.873	EPSD	COSMIC	7.780	Loss
AGC_Akt_AKT1_ST	Q7Z5H3	ARHGAP22	P31749	AKT1	S441	S437N	437	Missense	distal	-4	no	9.968	9.401	EPSD	COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	Q7Z5H3	ARHGAP22	P31749	AKT1	S441	G446R	446	Missense	distal	5	no	9.968	10.038	EPSD	COSMIC	7.780	Up-regulation
AGC_Akt_AKT1_ST	Q7Z5H3	ARHGAP22	P31749	AKT1	S447	G444R	444	Missense	distal	-3	no	6.025	12.781	EPSD	COSMIC	7.780	Gain
AGC_Akt_AKT1_ST	Q7Z5H3	ARHGAP22	P31749	AKT1	S467	G464R	464	Missense	distal	-3	no	4.401	11.157	EPSD	COSMIC	7.780	Gain
AGC_Akt_AKT1_ST	Q7Z5H3	ARHGAP22	P31749	AKT1	S476	S483T	483	Missense	distal	7	no	12.616	12.626	EPSD	COSMIC	7.780	Up-regulation
AGC_Akt_AKT1_ST	Q7Z5H3	ARHGAP22	P31749	AKT1	S476	R479W	479	Missense	distal	3	no	12.616	12.504	EPSD	COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	Q7Z5H3	ARHGAP22	P31749	AKT1	S476	R473S	473	Missense	distal	-3	no	12.616	4.839	EPSD	COSMIC	7.780	Loss
AGC_Akt_AKT1_ST	Q7Z5H3	ARHGAP22	P31749	AKT1	S476	R473K	473	Missense	distal	-3	no	12.616	8.096	EPSD	COSMIC	7.780	Down-regulation
AGC_Akt_AKT1_ST	Q7Z5H3	ARHGAP22	P31749	AKT1	S636	E640G	640	Missense	distal	4	no	8.147	8.243	EPSD	COSMIC;GDSC;CCLE	7.780	Up-regulation
TK_Src_SrcB_LYN_Y	Q9GZY6	LAT2	P07948	LYN	Y110	E108K	108	Missense	proximal	-2	no	3.541	2.827	EPSD;PhosphoSitePlus	COSMIC	1.526	Down-regulation
TK_Src_SrcB_LYN_Y	Q9GZY6	LAT2	P07948	LYN	Y110	G105E	105	Missense	distal	-5	no	3.541	4.444	EPSD;PhosphoSitePlus	COSMIC	1.526	Up-regulation
TK_Src_SrcB_LYN_Y	Q9GZY6	LAT2	P07948	LYN	Y136	E137V	137	Missense	proximal	1	no	3.254	2.958	EPSD;PhosphoSitePlus	COSMIC	1.526	Down-regulation
TK_Src_SrcB_LYN_Y	P30419	NMT1	P07948	LYN	Y117	T122M	122	Missense	distal	5	no	2.734	2.546	EPSD	COSMIC;GDSC;CCLE	1.526	Down-regulation
TK_Src_SrcB_LYN_Y	P30419	NMT1	P07948	LYN	Y180	T174S	174	Missense	distal	-6	no	3.896	3.616	PhosphoSitePlus	COSMIC	1.526	Down-regulation
TK_Src_SrcB_LYN_Y	P30419	NMT1	P07948	LYN	Y180	T174A	174	Missense	distal	-6	no	3.896	3.513	PhosphoSitePlus	COSMIC	1.526	Down-regulation
TK_Src_SrcB_LYN_Y	P02730	SLC4A1	P07948	LYN	Y8	M11T	11	Missense	distal	3	no	2.139	1.147	EPSD;PhosphoSitePlus	COSMIC	1.526	Loss
TK_Src_SrcB_LYN_Y	P02730	SLC4A1	P07948	LYN	Y8	D6Y	6	Missense	proximal	-2	no	2.139	1.227	EPSD;PhosphoSitePlus	COSMIC	1.526	Loss
TK_Src_SrcB_LYN_Y	P02730	SLC4A1	P07948	LYN	Y21	E17Q	17	Missense	distal	-4	no	3.161	3.479	EPSD;PhosphoSitePlus	COSMIC	1.526	Up-regulation
TK_Src_SrcB_LYN_Y	P02730	SLC4A1	P07948	LYN	Y21	Y21C	21	Missense	central	0	yes	3.161	0.000	EPSD;PhosphoSitePlus	COSMIC	1.526	Loss
TK_Src_SrcB_LYN_Y	P02730	SLC4A1	P07948	LYN	Y359	N365S	365	Missense	distal	6	no	5.387	5.207	EPSD;PhosphoSitePlus	COSMIC	1.526	Down-regulation
TK_Src_SrcB_LYN_Y	P02730	SLC4A1	P07948	LYN	Y359	D355N	355	Missense	distal	-4	no	5.387	4.952	EPSD;PhosphoSitePlus	COSMIC	1.526	Down-regulation
TK_Src_SrcB_LYN_Y	P00519	ABL1	P07948	LYN	Y70	G76E	76	Missense	distal	6	no	3.222	3.335	EPSD;PhosphoSitePlus	COSMIC	1.526	Up-regulation
TK_Src_SrcB_LYN_Y	P00519	ABL1	P07948	LYN	Y70	D77E	77	Missense	distal	7	no	3.222	3.233	EPSD;PhosphoSitePlus	COSMIC	1.526	Up-regulation
TK_Src_SrcB_LYN_Y	P00519	ABL1	P07948	LYN	Y70	S75G	75	Missense	distal	5	no	3.222	4.633	EPSD;PhosphoSitePlus	COSMIC	1.526	Up-regulation
TK_Src_SrcB_LYN_Y	P00519	ABL1	P07948	LYN	Y70	V67I	67	Missense	distal	-3	no	3.222	2.150	EPSD;PhosphoSitePlus	COSMIC	1.526	Down-regulation
TK_Src_SrcB_LYN_Y	P00519	ABL1	P07948	LYN	Y115	G109V	109	Missense	distal	-6	no	4.726	5.245	EPSD;PhosphoSitePlus	COSMIC	1.526	Up-regulation
TK_Src_SrcB_LYN_Y	P00519	ABL1	P07948	LYN	Y128	K124N	124	Missense	distal	-4	no	3.089	3.275	EPSD;PhosphoSitePlus	COSMIC	1.526	Up-regulation
TK_Src_SrcB_LYN_Y	P00519	ABL1	P07948	LYN	Y128	P131L	131	Missense	distal	3	no	3.089	2.439	EPSD;PhosphoSitePlus	COSMIC	1.526	Down-regulation
TK_Src_SrcB_LYN_Y	P00519	ABL1	P07948	LYN	Y128	R134H	134	Missense	distal	6	no	3.089	2.968	EPSD;PhosphoSitePlus	COSMIC	1.526	Down-regulation
TK_Src_SrcB_LYN_Y	P00519	ABL1	P07948	LYN	Y139	G144E	144	Missense	distal	5	no	5.477	3.682	EPSD;PhosphoSitePlus	COSMIC	1.526	Down-regulation
TK_Src_SrcB_LYN_Y	P00519	ABL1	P07948	LYN	Y139	A137S	137	Missense	proximal	-2	no	5.477	6.361	EPSD;PhosphoSitePlus	COSMIC	1.526	Up-regulation
TK_Src_SrcB_LYN_Y	P00519	ABL1	P07948	LYN	Y139	R134H	134	Missense	distal	-5	no	5.477	4.799	EPSD;PhosphoSitePlus	COSMIC	1.526	Down-regulation
TK_Src_SrcB_LYN_Y	P00519	ABL1	P07948	LYN	Y172	R166K	166	Missense	distal	-6	no	5.321	5.302	EPSD;PhosphoSitePlus	COSMIC;CCLE	1.526	Down-regulation
TK_Src_SrcB_LYN_Y	P00519	ABL1	P07948	LYN	Y172	E168K	168	Missense	distal	-4	no	5.321	4.948	EPSD;PhosphoSitePlus	COSMIC	1.526	Down-regulation
TK_Src_SrcB_LYN_Y	P00519	ABL1	P07948	LYN	Y172	Y167H	167	Missense	distal	-5	no	5.321	6.184	EPSD;PhosphoSitePlus	COSMIC	1.526	Up-regulation
TK_Src_SrcB_LYN_Y	P00519	ABL1	P07948	LYN	Y185	R191C	191	Missense	distal	6	no	2.945	2.481	EPSD;PhosphoSitePlus	COSMIC	1.526	Down-regulation
TK_Src_SrcB_LYN_Y	P00519	ABL1	P07948	LYN	Y185	S187F	187	Missense	proximal	2	no	2.945	3.150	EPSD;PhosphoSitePlus	COSMIC	1.526	Up-regulation
TK_Src_SrcB_LYN_Y	P00519	ABL1	P07948	LYN	Y185	L184R	184	Missense	proximal	-1	no	2.945	2.001	EPSD;PhosphoSitePlus	COSMIC	1.526	Down-regulation
TK_Src_SrcB_LYN_Y	P00519	ABL1	P07948	LYN	Y215	R220H	220	Missense	distal	5	no	1.584	0.816	EPSD;PhosphoSitePlus	COSMIC	1.526	Loss
TK_Src_SrcB_LYN_Y	P00519	ABL1	P07948	LYN	Y215	P218S	218	Missense	distal	3	no	1.584	-0.760	EPSD;PhosphoSitePlus	COSMIC	1.526	Loss
TK_Src_SrcB_LYN_Y	P00519	ABL1	P07948	LYN	Y215	T212R	212	Missense	distal	-3	no	1.584	-0.368	EPSD;PhosphoSitePlus	COSMIC	1.526	Loss
TK_Src_SrcB_LYN_Y	P00519	ABL1	P07948	LYN	Y226	R220H	220	Missense	distal	-6	no	3.025	3.400	EPSD;PhosphoSitePlus	COSMIC	1.526	Up-regulation
TK_Src_SrcB_LYN_Y	P00519	ABL1	P07948	LYN	Y226	N231S	231	Missense	distal	5	no	3.025	2.417	EPSD;PhosphoSitePlus	COSMIC	1.526	Down-regulation
TK_Src_SrcB_LYN_Y	P00519	ABL1	P07948	LYN	Y226	G227S	227	Missense	proximal	1	no	3.025	3.374	EPSD;PhosphoSitePlus	COSMIC	1.526	Up-regulation
TK_Src_SrcB_LYN_Y	P00519	ABL1	P07948	LYN	Y226	N231K	231	Missense	distal	5	no	3.025	3.709	EPSD;PhosphoSitePlus	COSMIC	1.526	Up-regulation
TK_Src_SrcB_LYN_Y	P00519	ABL1	P07948	LYN	Y232	N231S	231	Missense	proximal	-1	no	2.013	0.716	EPSD	COSMIC	1.526	Loss
TK_Src_SrcB_LYN_Y	P00519	ABL1	P07948	LYN	Y232	M237I	237	Missense	distal	5	no	2.013	2.490	EPSD	COSMIC	1.526	Up-regulation
TK_Src_SrcB_LYN_Y	P00519	ABL1	P07948	LYN	Y232	G227S	227	Missense	distal	-5	no	2.013	2.306	EPSD	COSMIC	1.526	Up-regulation
TK_Src_SrcB_LYN_Y	P00519	ABL1	P07948	LYN	Y232	N231K	231	Missense	proximal	-1	no	2.013	1.891	EPSD	COSMIC	1.526	Down-regulation
TK_Src_SrcB_LYN_Y	P00519	ABL1	P07948	LYN	Y232	E238K	238	Missense	distal	6	no	2.013	1.952	EPSD	COSMIC	1.526	Down-regulation
TK_Src_SrcB_LYN_Y	P00519	ABL1	P07948	LYN	Y232	W235L	235	Missense	distal	3	no	2.013	0.928	EPSD	COSMIC	1.526	Loss
TK_Src_SrcB_LYN_Y	P00519	ABL1	P07948	LYN	Y393	R386Q	386	Missense	distal	-7	no	4.563	4.526	PhosphoSitePlus;EPSD	COSMIC	1.526	Down-regulation
TK_Src_SrcB_LYN_Y	P00519	ABL1	P07948	LYN	Y393	A397P	397	Missense	distal	4	no	4.563	4.780	PhosphoSitePlus;EPSD	COSMIC	1.526	Up-regulation
TK_Src_SrcB_LYN_Y	P00519	ABL1	P07948	LYN	Y393	H396R	396	Missense	distal	3	no	4.563	6.384	PhosphoSitePlus;EPSD	COSMIC	1.526	Up-regulation
TK_Src_SrcB_LYN_Y	P00519	ABL1	P07948	LYN	Y393	L387M	387	Missense	distal	-6	no	4.563	5.061	PhosphoSitePlus;EPSD	COSMIC	1.526	Up-regulation
TK_Src_SrcB_LYN_Y	P00519	ABL1	P07948	LYN	Y393	M388L	388	Missense	distal	-5	no	4.563	4.068	PhosphoSitePlus;EPSD	COSMIC	1.526	Down-regulation
TK_Src_SrcB_LYN_Y	P00519	ABL1	P07948	LYN	Y393	G398R	398	Missense	distal	5	no	4.563	3.829	PhosphoSitePlus;EPSD	COSMIC	1.526	Down-regulation
TK_Src_SrcB_LYN_Y	P00519	ABL1	P07948	LYN	Y393	A399T	399	Missense	distal	6	no	4.563	4.557	PhosphoSitePlus;EPSD	COSMIC	1.526	Down-regulation
TK_Src_SrcB_LYN_Y	P00519	ABL1	P07948	LYN	Y393	T389A	389	Missense	distal	-4	no	4.563	4.756	PhosphoSitePlus;EPSD	COSMIC	1.526	Up-regulation
TK_Src_SrcB_LYN_Y	P00519	ABL1	P07948	LYN	Y393	K400E	400	Missense	distal	7	no	4.563	4.522	PhosphoSitePlus;EPSD	COSMIC	1.526	Down-regulation
TK_Src_SrcB_LYN_Y	P00519	ABL1	P07948	LYN	Y393	T394A	394	Missense	proximal	1	no	4.563	3.244	PhosphoSitePlus;EPSD	COSMIC	1.526	Down-regulation
TK_Src_SrcB_LYN_Y	P00519	ABL1	P07948	LYN	Y393	H396P	396	Missense	distal	3	no	4.563	7.824	PhosphoSitePlus;EPSD	COSMIC	1.526	Up-regulation
TK_Src_SrcB_LYN_Y	P00519	ABL1	P07948	LYN	Y393	D391N	391	Missense	proximal	-2	no	4.563	4.496	PhosphoSitePlus;EPSD	COSMIC	1.526	Down-regulation
TK_Src_SrcB_LYN_Y	P00519	ABL1	P07948	LYN	Y393	L387F	387	Missense	distal	-6	no	4.563	5.002	PhosphoSitePlus;EPSD	COSMIC	1.526	Up-regulation
TK_Src_SrcB_LYN_Y	P00519	ABL1	P07948	LYN	Y393	H396Y	396	Missense	distal	3	no	4.563	3.511	PhosphoSitePlus;EPSD	COSMIC	1.526	Down-regulation
TK_Src_SrcB_LYN_Y	P00519	ABL1	P07948	LYN	Y393	G390W	390	Missense	distal	-3	no	4.563	3.422	PhosphoSitePlus;EPSD	COSMIC	1.526	Down-regulation
TK_Src_SrcB_LYN_Y	P00519	ABL1	P07948	LYN	Y1064	F1066L	1066	Missense	proximal	2	no	2.096	1.723	EPSD	COSMIC	1.526	Down-regulation
TK_Src_SrcB_LYN_Y	P00519	ABL1	P07948	LYN	Y1064	C1067R	1067	Missense	distal	3	no	2.096	1.681	EPSD	COSMIC	1.526	Down-regulation
TK_Src_SrcB_LYN_Y	P00519	ABL1	P07948	LYN	Y1064	L1063H	1063	Missense	proximal	-1	no	2.096	2.370	EPSD	COSMIC	1.526	Up-regulation
TK_Src_SrcB_LYN_Y	P00519	ABL1	P07948	LYN	Y1064	T1065S	1065	Missense	proximal	1	no	2.096	1.828	EPSD	COSMIC	1.526	Down-regulation
TK_Src_SrcB_LYN_Y	P25490	YY1	P07948	LYN	Y8	D5N	5	Missense	distal	-3	no	2.606	2.565	PhosphoSitePlus;EPSD	COSMIC	1.526	Down-regulation
TK_Src_SrcB_LYN_Y	P25490	YY1	P07948	LYN	Y254	P249S	249	Missense	distal	-5	no	2.433	2.199	EPSD;PhosphoSitePlus	COSMIC	1.526	Down-regulation
TK_Src_SrcB_LYN_Y	P25490	YY1	P07948	LYN	Y254	E253K	253	Missense	proximal	-1	no	2.433	1.756	EPSD;PhosphoSitePlus	COSMIC	1.526	Down-regulation
TK_Src_SrcB_LYN_Y	P25490	YY1	P07948	LYN	Y383	R381M	381	Missense	proximal	-2	no	3.286	0.811	EPSD;PhosphoSitePlus	COSMIC;CCLE	1.526	Loss
TK_Src_SrcB_LYN_Y	P25490	YY1	P07948	LYN	Y383	C385F	385	Missense	proximal	2	no	3.286	4.424	EPSD;PhosphoSitePlus	COSMIC	1.526	Up-regulation
TK_Src_SrcB_LYN_Y	O43823	AKAP8	P07948	LYN	Y51	T50A	50	Missense	proximal	-1	no	5.524	3.907	EPSD;PhosphoSitePlus	COSMIC	1.526	Down-regulation
TK_Src_SrcB_LYN_Y	O43823	AKAP8	P07948	LYN	Y53	T50A	50	Missense	distal	-3	no	2.068	0.132	PhosphoSitePlus;EPSD	COSMIC	1.526	Loss
TK_Src_SrcB_LYN_Y	O43823	AKAP8	P07948	LYN	Y80	T86I	86	Missense	distal	6	no	1.900	1.780	EPSD;PhosphoSitePlus	COSMIC	1.526	Down-regulation
TK_Src_SrcB_LYN_Y	O43823	AKAP8	P07948	LYN	Y80	D87N	87	Missense	distal	7	no	1.900	1.920	EPSD;PhosphoSitePlus	COSMIC	1.526	Up-regulation
TK_Src_SrcB_LYN_Y	O43823	AKAP8	P07948	LYN	Y80	S79P	79	Missense	proximal	-1	no	1.900	3.206	EPSD;PhosphoSitePlus	COSMIC	1.526	Up-regulation
TK_Src_SrcB_LYN_Y	O43823	AKAP8	P07948	LYN	Y146	D153N	153	Missense	distal	7	no	4.024	4.044	EPSD;PhosphoSitePlus	COSMIC;GDSC;CCLE	1.526	Up-regulation
TK_Src_SrcB_LYN_Y	O43823	AKAP8	P07948	LYN	Y146	N144S	144	Missense	proximal	-2	no	4.024	4.569	EPSD;PhosphoSitePlus	COSMIC	1.526	Up-regulation
TK_Src_SrcB_LYN_Y	O43823	AKAP8	P07948	LYN	Y150	F156L	156	Missense	distal	6	no	2.172	2.361	EPSD;PhosphoSitePlus	COSMIC	1.526	Up-regulation
TK_Src_SrcB_LYN_Y	O43823	AKAP8	P07948	LYN	Y150	D153N	153	Missense	distal	3	no	2.172	2.892	EPSD;PhosphoSitePlus	COSMIC;GDSC;CCLE	1.526	Up-regulation
TK_Src_SrcB_LYN_Y	O43823	AKAP8	P07948	LYN	Y150	N144S	144	Missense	distal	-6	no	2.172	2.041	EPSD;PhosphoSitePlus	COSMIC	1.526	Down-regulation
TK_Src_SrcB_LYN_Y	O43823	AKAP8	P07948	LYN	Y154	F156L	156	Missense	proximal	2	no	2.317	1.943	EPSD;PhosphoSitePlus	COSMIC	1.526	Down-regulation
TK_Src_SrcB_LYN_Y	O43823	AKAP8	P07948	LYN	Y154	D153N	153	Missense	proximal	-1	no	2.317	2.118	EPSD;PhosphoSitePlus	COSMIC;GDSC;CCLE	1.526	Down-regulation
TK_Src_SrcB_LYN_Y	O43823	AKAP8	P07948	LYN	Y154	D161N	161	Missense	distal	7	no	2.317	2.336	EPSD;PhosphoSitePlus	COSMIC	1.526	Up-regulation
TK_Src_SrcB_LYN_Y	O43823	AKAP8	P07948	LYN	Y170	A177T	177	Missense	distal	7	no	1.993	1.963	EPSD;PhosphoSitePlus	COSMIC	1.526	Down-regulation
TK_Src_SrcB_LYN_Y	O43823	AKAP8	P07948	LYN	Y170	R174Q	174	Missense	distal	4	no	1.993	1.873	EPSD;PhosphoSitePlus	COSMIC;CCLE	1.526	Down-regulation
TK_Src_SrcB_LYN_Y	O43823	AKAP8	P07948	LYN	Y170	C173Y	173	Missense	distal	3	no	1.993	-1.296	EPSD;PhosphoSitePlus	COSMIC	1.526	Loss
TK_Src_SrcB_LYN_Y	O43823	AKAP8	P07948	LYN	Y170	D175N	175	Missense	distal	5	no	1.993	1.847	EPSD;PhosphoSitePlus	COSMIC	1.526	Down-regulation
TK_Src_SrcB_LYN_Y	O43823	AKAP8	P07948	LYN	Y170	G168W	168	Missense	proximal	-2	no	1.993	-2.555	EPSD;PhosphoSitePlus	COSMIC	1.526	Loss
TK_Src_SrcB_LYN_Y	O43823	AKAP8	P07948	LYN	Y229	G234D	234	Missense	distal	5	no	2.645	1.990	EPSD	COSMIC	1.526	Down-regulation
TK_Src_SrcB_LYN_Y	O43823	AKAP8	P07948	LYN	Y311	F308C	308	Missense	distal	-3	no	4.451	4.361	EPSD;PhosphoSitePlus	COSMIC	1.526	Down-regulation
TK_Src_SrcB_LYN_Y	O43823	AKAP8	P07948	LYN	Y311	R305W	305	Missense	distal	-6	no	4.451	4.190	EPSD;PhosphoSitePlus	COSMIC;CCLE	1.526	Down-regulation
TK_Src_SrcB_LYN_Y	O43823	AKAP8	P07948	LYN	Y311	E312K	312	Missense	proximal	1	no	4.451	3.464	EPSD;PhosphoSitePlus	COSMIC	1.526	Down-regulation
TK_Src_SrcB_LYN_Y	P31995	FCGR2C	P07948	LYN	Y287	G292S	292	Missense	distal	5	no	4.381	2.970	EPSD	COSMIC	1.526	Down-regulation
TK_Src_SrcB_LYN_Y	P31995	FCGR2C	P07948	LYN	Y294	G292S	292	Missense	proximal	-2	no	1.837	2.814	EPSD	COSMIC	1.526	Up-regulation
TK_Src_SrcB_LYN_Y	P11274	BCR	P07948	LYN	Y177	E181D	181	Missense	distal	4	no	5.347	5.195	PhosphoSitePlus	COSMIC	1.526	Down-regulation
TK_Src_SrcB_LYN_Y	P11274	BCR	P07948	LYN	Y246	G241S	241	Missense	distal	-5	no	3.979	4.272	EPSD	COSMIC	1.526	Up-regulation
TK_Src_SrcB_LYN_Y	P11274	BCR	P07948	LYN	Y279	I282M	282	Missense	distal	3	no	2.613	2.858	EPSD	COSMIC	1.526	Up-regulation
TK_Src_SrcB_LYN_Y	P11274	BCR	P07948	LYN	Y279	E275D	275	Missense	distal	-4	no	2.613	2.861	EPSD	COSMIC	1.526	Up-regulation
TK_Src_SrcB_LYN_Y	P11274	BCR	P07948	LYN	Y279	P278S	278	Missense	proximal	-1	no	2.613	1.308	EPSD	COSMIC	1.526	Loss
TK_Src_SrcB_LYN_Y	P11274	BCR	P07948	LYN	Y279	P272L	272	Missense	distal	-7	no	2.613	2.367	EPSD	COSMIC	1.526	Down-regulation
TK_Src_SrcB_LYN_Y	P11274	BCR	P07948	LYN	Y279	V284L	284	Missense	distal	5	no	2.613	3.777	EPSD	COSMIC	1.526	Up-regulation
TK_Src_SrcB_LYN_Y	P11274	BCR	P07948	LYN	Y283	I282M	282	Missense	proximal	-1	no	2.669	2.423	EPSD	COSMIC	1.526	Down-regulation
TK_Src_SrcB_LYN_Y	P11274	BCR	P07948	LYN	Y283	E289G	289	Missense	distal	6	no	2.669	2.556	EPSD	COSMIC	1.526	Down-regulation
TK_Src_SrcB_LYN_Y	P11274	BCR	P07948	LYN	Y283	P278S	278	Missense	distal	-5	no	2.669	2.435	EPSD	COSMIC	1.526	Down-regulation
TK_Src_SrcB_LYN_Y	P11274	BCR	P07948	LYN	Y283	V284L	284	Missense	proximal	1	no	2.669	1.467	EPSD	COSMIC	1.526	Loss
TK_Src_SrcB_LYN_Y	P11274	BCR	P07948	LYN	Y360	R364Q	364	Missense	distal	4	no	2.787	2.667	EPSD	COSMIC	1.526	Down-regulation
TK_Src_SrcB_LYN_Y	P11274	BCR	P07948	LYN	Y360	M362I	362	Missense	proximal	2	no	2.787	2.381	EPSD	COSMIC	1.526	Down-regulation
TK_Src_SrcB_LYN_Y	P11274	BCR	P07948	LYN	Y455	L453Q	453	Missense	proximal	-2	no	0.066	1.635	EPSD	COSMIC	1.526	Gain
TK_Src_SrcB_LYN_Y	P11274	BCR	P07948	LYN	Y561	F560L	560	Missense	proximal	-1	no	2.514	2.118	EPSD	COSMIC	1.526	Down-regulation
TK_Src_SrcB_LYN_Y	P11274	BCR	P07948	LYN	Y561	R567H	567	Missense	distal	6	no	2.514	2.394	EPSD	COSMIC;GDSC;CCLE	1.526	Down-regulation
TK_Src_SrcB_LYN_Y	P11274	BCR	P07948	LYN	Y561	E555K	555	Missense	distal	-6	no	2.514	2.083	EPSD	COSMIC	1.526	Down-regulation
TK_Src_SrcB_LYN_Y	P11274	BCR	P07948	LYN	Y910	S906F	906	Missense	distal	-4	no	2.129	1.642	EPSD	COSMIC	1.526	Down-regulation
TK_Src_SrcB_LYN_Y	O15492	RGS16	P07948	LYN	Y168	T161I	161	Missense	distal	-7	no	3.923	4.232	EPSD;PhosphoSitePlus	COSMIC	1.526	Up-regulation
TK_Src_SrcB_LYN_Y	Q06187	BTK	P07948	LYN	Y223	L222F	222	Missense	proximal	-1	no	2.734	3.130	PhosphoSitePlus;EPSD	COSMIC	1.526	Up-regulation
TK_Src_SrcB_LYN_Y	Q06187	BTK	P07948	LYN	Y223	D224N	224	Missense	proximal	1	no	2.734	2.744	PhosphoSitePlus;EPSD	COSMIC	1.526	Up-regulation
TK_Src_SrcB_LYN_Y	Q06187	BTK	P07948	LYN	Y223	K217R	217	Missense	distal	-6	no	2.734	2.753	PhosphoSitePlus;EPSD	COSMIC	1.526	Up-regulation
TK_Src_SrcB_LYN_Y	Q06187	BTK	P07948	LYN	Y551	L547Q	547	Missense	distal	-4	no	6.089	7.599	EPSD;PhosphoSitePlus	COSMIC	1.526	Up-regulation
TK_Src_SrcB_LYN_Y	Q06187	BTK	P07948	LYN	Y551	R544W	544	Missense	distal	-7	no	6.089	6.203	EPSD;PhosphoSitePlus	COSMIC	1.526	Up-regulation
TK_Src_SrcB_LYN_Y	Q06187	BTK	P07948	LYN	Y551	S553R	553	Missense	proximal	2	no	6.089	5.926	EPSD;PhosphoSitePlus	COSMIC	1.526	Down-regulation
TK_Src_SrcB_LYN_Y	Q06187	BTK	P07948	LYN	Y551	R544M	544	Missense	distal	-7	no	6.089	6.242	EPSD;PhosphoSitePlus	COSMIC	1.526	Up-regulation
TK_Src_SrcB_LYN_Y	Q06187	BTK	P07948	LYN	Y551	E550K	550	Missense	proximal	-1	no	6.089	5.412	EPSD;PhosphoSitePlus	COSMIC	1.526	Down-regulation
TK_Src_SrcB_LYN_Y	P12318	FCGR2A	P07948	LYN	Y281	T277I	277	Missense	distal	-4	no	4.134	2.221	EPSD	COSMIC	1.526	Down-regulation
TK_Src_SrcB_LYN_Y	P12318	FCGR2A	P07948	LYN	Y281	G286D	286	Missense	distal	5	no	4.134	3.479	EPSD	COSMIC	1.526	Down-regulation
TK_Src_SrcB_LYN_Y	P12318	FCGR2A	P07948	LYN	Y281	G286S	286	Missense	distal	5	no	4.134	2.724	EPSD	COSMIC;CCLE	1.526	Down-regulation
TK_Src_SrcB_LYN_Y	P12318	FCGR2A	P07948	LYN	Y288	G286D	286	Missense	proximal	-2	no	2.252	2.751	EPSD	COSMIC	1.526	Up-regulation
TK_Src_SrcB_LYN_Y	P12318	FCGR2A	P07948	LYN	Y288	G286S	286	Missense	proximal	-2	no	2.252	3.229	EPSD	COSMIC;CCLE	1.526	Up-regulation
TK_Src_SrcB_LYN_Y	P32927	CSF2RB	P07948	LYN	Y822	L825F	825	Missense	distal	3	no	3.906	3.045	EPSD;PhosphoSitePlus	COSMIC	1.526	Down-regulation
TK_Src_SrcB_LYN_Y	P15391	CD19	P07948	LYN	Y348	G341E	341	Missense	distal	-7	no	2.608	2.855	EPSD	COSMIC	1.526	Up-regulation
TK_Src_SrcB_LYN_Y	P15391	CD19	P07948	LYN	Y378	G373S	373	Missense	distal	-5	no	3.346	3.638	EPSD	COSMIC	1.526	Up-regulation
TK_Src_SrcB_LYN_Y	P15391	CD19	P07948	LYN	Y378	S377P	377	Missense	proximal	-1	no	3.346	4.651	EPSD	COSMIC	1.526	Up-regulation
TK_Src_SrcB_LYN_Y	P15391	CD19	P07948	LYN	Y439	S433F	433	Missense	distal	-6	no	2.774	2.876	EPSD	COSMIC	1.526	Up-regulation
TK_Src_SrcB_LYN_Y	P15391	CD19	P07948	LYN	Y439	G436C	436	Missense	distal	-3	no	2.774	1.916	EPSD	COSMIC;GDSC;CCLE	1.526	Down-regulation
TK_Src_SrcB_LYN_Y	P15391	CD19	P07948	LYN	Y500	M503I	503	Missense	distal	3	no	2.374	2.130	EPSD;PhosphoSitePlus	COSMIC	1.526	Down-regulation
TK_Src_SrcB_LYN_Y	P15391	CD19	P07948	LYN	Y500	E501K	501	Missense	proximal	1	no	2.374	1.388	EPSD;PhosphoSitePlus	COSMIC	1.526	Loss
TK_Src_SrcB_LYN_Y	P15391	CD19	P07948	LYN	Y500	Y500C	500	Missense	central	0	yes	2.374	0.000	EPSD;PhosphoSitePlus	COSMIC	1.526	Loss
TK_Src_SrcB_LYN_Y	P15391	CD19	P07948	LYN	Y500	S497F	497	Missense	distal	-3	no	2.374	1.253	EPSD;PhosphoSitePlus	COSMIC	1.526	Loss
TK_Src_SrcB_LYN_Y	P15391	CD19	P07948	LYN	Y500	D502N	502	Missense	proximal	2	no	2.374	2.238	EPSD;PhosphoSitePlus	COSMIC	1.526	Down-regulation
TK_Src_SrcB_LYN_Y	P15391	CD19	P07948	LYN	Y500	G496E	496	Missense	distal	-4	no	2.374	3.437	EPSD;PhosphoSitePlus	COSMIC	1.526	Up-regulation
TK_Src_SrcB_LYN_Y	P15391	CD19	P07948	LYN	Y531	P537T	537	Missense	distal	6	no	6.658	6.389	PhosphoSitePlus;EPSD	COSMIC;CCLE	1.526	Down-regulation
TK_Src_SrcB_LYN_Y	P15391	CD19	P07948	LYN	Y531	D529A	529	Missense	proximal	-2	no	6.658	6.252	PhosphoSitePlus;EPSD	COSMIC	1.526	Down-regulation
TK_Src_SrcB_LYN_Y	P15391	CD19	P07948	LYN	Y531	N533S	533	Missense	proximal	2	no	6.658	6.648	PhosphoSitePlus;EPSD	COSMIC	1.526	Down-regulation
TK_Src_SrcB_LYN_Y	P15391	CD19	P07948	LYN	Y531	M534I	534	Missense	distal	3	no	6.658	6.413	PhosphoSitePlus;EPSD	COSMIC	1.526	Down-regulation
TK_Src_SrcB_LYN_Y	P15391	CD19	P07948	LYN	Y531	E532K	532	Missense	proximal	1	no	6.658	5.671	PhosphoSitePlus;EPSD	COSMIC	1.526	Down-regulation
TK_Src_SrcB_LYN_Y	P15391	CD19	P07948	LYN	Y531	D529N	529	Missense	proximal	-2	no	6.658	6.591	PhosphoSitePlus;EPSD	COSMIC	1.526	Down-regulation
TK_Src_SrcB_LYN_Y	Q13568	IRF5	P07948	LYN	Y136	P132S	132	Missense	distal	-4	no	1.247	2.544	EPSD	COSMIC	1.526	Gain
TK_Src_SrcB_LYN_Y	Q13568	IRF5	P07948	LYN	Y335	R338Q	338	Missense	distal	3	no	5.361	4.179	EPSD;PhosphoSitePlus	COSMIC	1.526	Down-regulation
TK_Src_SrcB_LYN_Y	Q13263	TRIM28	P07948	LYN	Y449	V445M	445	Missense	distal	-4	no	3.114	3.248	EPSD;PhosphoSitePlus	COSMIC	1.526	Up-regulation
TK_Src_SrcB_LYN_Y	Q13263	TRIM28	P07948	LYN	Y449	P442L	442	Missense	distal	-7	no	3.114	2.868	EPSD;PhosphoSitePlus	COSMIC;GDSC	1.526	Down-regulation
TK_Src_SrcB_LYN_Y	Q13263	TRIM28	P07948	LYN	Y517	E523D	523	Missense	distal	6	no	3.224	3.344	PhosphoSitePlus;EPSD	COSMIC	1.526	Up-regulation
TK_Src_SrcB_LYN_Y	Q14790	CASP8	P07948	LYN	Y235	G234E	234	Missense	proximal	-1	no	0.693	2.519	EPSD	COSMIC	1.526	Gain
TK_Src_SrcB_LYN_Y	Q14790	CASP8	P07948	LYN	Y334	A331T	331	Missense	distal	-3	no	1.011	2.946	EPSD	COSMIC	1.526	Gain
TK_Src_SrcB_LYN_Y	Q14790	CASP8	P07948	LYN	Y334	Q339R	339	Missense	distal	5	no	1.011	2.238	EPSD	COSMIC	1.526	Gain
TK_Src_SrcB_LYN_Y	Q14790	CASP8	P07948	LYN	Y334	G328V	328	Missense	distal	-6	no	1.011	1.530	EPSD	COSMIC	1.526	Gain
TK_Src_SrcB_LYN_Y	Q14790	CASP8	P07948	LYN	Y334	G328E	328	Missense	distal	-6	no	1.011	1.554	EPSD	COSMIC	1.526	Gain
TK_Src_SrcB_LYN_Y	Q14790	CASP8	P07948	LYN	Y380	P379L	379	Missense	proximal	-1	no	5.343	4.677	PhosphoSitePlus;EPSD	COSMIC	1.526	Down-regulation
TK_Src_SrcB_LYN_Y	Q14790	CASP8	P07948	LYN	Y380	P379S	379	Missense	proximal	-1	no	5.343	4.037	PhosphoSitePlus;EPSD	COSMIC	1.526	Down-regulation
TK_Src_SrcB_LYN_Y	Q14790	CASP8	P07948	LYN	Y380	L385P	385	Missense	distal	5	no	5.343	4.677	PhosphoSitePlus;EPSD	COSMIC	1.526	Down-regulation
TK_Src_SrcB_LYN_Y	Q14790	CASP8	P07948	LYN	Y380	P379Q	379	Missense	proximal	-1	no	5.343	4.902	PhosphoSitePlus;EPSD	COSMIC	1.526	Down-regulation
TK_Src_SrcB_LYN_Y	Q14790	CASP8	P07948	LYN	Y380	P379T	379	Missense	proximal	-1	no	5.343	6.090	PhosphoSitePlus;EPSD	COSMIC	1.526	Up-regulation
TK_Src_SrcB_LYN_Y	Q14790	CASP8	P07948	LYN	Y380	S375L	375	Missense	distal	-5	no	5.343	4.646	PhosphoSitePlus;EPSD	COSMIC	1.526	Down-regulation
TK_Src_SrcB_LYN_Y	Q14790	CASP8	P07948	LYN	Y380	D384N	384	Missense	distal	4	no	5.343	5.506	PhosphoSitePlus;EPSD	COSMIC	1.526	Up-regulation
TK_Src_SrcB_LYN_Y	Q14790	CASP8	P07948	LYN	Y380	E376V	376	Missense	distal	-4	no	5.343	4.233	PhosphoSitePlus;EPSD	COSMIC	1.526	Down-regulation
TK_Src_SrcB_LYN_Y	Q14790	CASP8	P07948	LYN	Y380	S386L	386	Missense	distal	6	no	5.343	5.291	PhosphoSitePlus;EPSD	COSMIC	1.526	Down-regulation
TK_Src_SrcB_LYN_Y	Q14790	CASP8	P07948	LYN	Y448	T441I	441	Missense	distal	-7	no	3.836	4.145	EPSD;PhosphoSitePlus	COSMIC	1.526	Up-regulation
TK_Src_SrcB_LYN_Y	Q14790	CASP8	P07948	LYN	Y448	I442T	442	Missense	distal	-6	no	3.836	4.364	EPSD;PhosphoSitePlus	COSMIC	1.526	Up-regulation
TK_Src_SrcB_LYN_Y	Q14790	CASP8	P07948	LYN	Y448	T444I	444	Missense	distal	-4	no	3.836	1.923	EPSD;PhosphoSitePlus	COSMIC	1.526	Down-regulation
TK_Src_SrcB_LYN_Y	Q14790	CASP8	P07948	LYN	Y448	D455H	455	Missense	distal	7	no	3.836	3.903	EPSD;PhosphoSitePlus	COSMIC	1.526	Up-regulation
TK_Src_SrcB_LYN_Y	Q14790	CASP8	P07948	LYN	Y448	D455G	455	Missense	distal	7	no	3.836	3.908	EPSD;PhosphoSitePlus	COSMIC	1.526	Up-regulation
TK_Src_SrcB_LYN_Y	Q14790	CASP8	P07948	LYN	Y448	D455V	455	Missense	distal	7	no	3.836	3.862	EPSD;PhosphoSitePlus	COSMIC	1.526	Up-regulation
TK_Src_SrcB_LYN_Y	Q14790	CASP8	P07948	LYN	Y448	D455N	455	Missense	distal	7	no	3.836	3.856	EPSD;PhosphoSitePlus	COSMIC	1.526	Up-regulation
TK_Src_SrcB_LYN_Y	Q14790	CASP8	P07948	LYN	Y448	D454G	454	Missense	distal	6	no	3.836	3.603	EPSD;PhosphoSitePlus	COSMIC	1.526	Down-regulation
TK_Src_SrcB_LYN_Y	Q14790	CASP8	P07948	LYN	Y448	T444P	444	Missense	distal	-4	no	3.836	2.258	EPSD;PhosphoSitePlus	COSMIC	1.526	Down-regulation
TK_Src_SrcB_LYN_Y	Q14790	CASP8	P07948	LYN	Y448	L443P	443	Missense	distal	-5	no	3.836	4.767	EPSD;PhosphoSitePlus	COSMIC	1.526	Up-regulation
TK_Src_SrcB_LYN_Y	P29350	PTPN6	P07948	LYN	Y306	I302N	302	Missense	distal	-4	no	2.085	3.936	EPSD	COSMIC	1.526	Up-regulation
TK_Src_SrcB_LYN_Y	P29350	PTPN6	P07948	LYN	Y377	N381K	381	Missense	distal	4	no	2.801	2.693	EPSD	COSMIC	1.526	Down-regulation
TK_Src_SrcB_LYN_Y	P29350	PTPN6	P07948	LYN	Y377	G375W	375	Missense	proximal	-2	no	2.801	-1.747	EPSD	COSMIC	1.526	Loss
TK_Src_SrcB_LYN_Y	P29350	PTPN6	P07948	LYN	Y536	E535G	535	Missense	proximal	-1	no	5.656	3.831	PhosphoSitePlus	COSMIC	1.526	Down-regulation
TK_Src_SrcB_LYN_Y	P29350	PTPN6	P07948	LYN	Y536	G537R	537	Missense	proximal	1	no	5.656	5.700	PhosphoSitePlus	COSMIC	1.526	Up-regulation
TK_Src_SrcB_LYN_Y	P29350	PTPN6	P07948	LYN	Y564	N571Y	571	Missense	distal	7	no	4.298	4.265	EPSD	COSMIC	1.526	Down-regulation
TK_Src_SrcB_LYN_Y	P46527	CDKN1B	P07948	LYN	Y74	G72A	72	Missense	proximal	-2	no	1.475	1.569	EPSD	COSMIC	1.526	Gain
TK_Src_SrcB_LYN_Y	P46527	CDKN1B	P07948	LYN	Y74	W76G	76	Missense	proximal	2	no	1.475	1.957	EPSD	COSMIC	1.526	Gain
TK_Src_SrcB_LYN_Y	P46527	CDKN1B	P07948	LYN	Y88	P91S	91	Missense	distal	3	no	4.687	2.344	PhosphoSitePlus	COSMIC	1.526	Down-regulation
TK_Src_SrcB_LYN_Y	P46527	CDKN1B	P07948	LYN	Y88	R90K	90	Missense	proximal	2	no	4.687	4.719	PhosphoSitePlus	COSMIC	1.526	Up-regulation
TK_Src_SrcB_LYN_Y	P46527	CDKN1B	P07948	LYN	Y88	R93W	93	Missense	distal	5	no	4.687	5.849	PhosphoSitePlus	COSMIC	1.526	Up-regulation
TK_Src_SrcB_LYN_Y	P46527	CDKN1B	P07948	LYN	Y88	P94L	94	Missense	distal	6	no	4.687	4.358	PhosphoSitePlus	COSMIC	1.526	Down-regulation
TK_Src_SrcB_LYN_Y	P46527	CDKN1B	P07948	LYN	Y88	Y88C	88	Missense	central	0	yes	4.687	0.000	PhosphoSitePlus	COSMIC	1.526	Loss
TK_Src_SrcB_LYN_Y	P60484	PTEN	P07948	LYN	Y27	D24A	24	Missense	distal	-3	no	1.661	0.914	EPSD	COSMIC	1.526	Loss
TK_Src_SrcB_LYN_Y	P60484	PTEN	P07948	LYN	Y27	F21S	21	Missense	distal	-6	no	1.661	1.558	EPSD	COSMIC	1.526	Down-regulation
TK_Src_SrcB_LYN_Y	P60484	PTEN	P07948	LYN	Y27	A34G	34	Missense	distal	7	no	1.661	1.728	EPSD	COSMIC	1.526	Up-regulation
TK_Src_SrcB_LYN_Y	P60484	PTEN	P07948	LYN	Y27	L23V	23	Missense	distal	-4	no	1.661	1.742	EPSD	COSMIC	1.526	Up-regulation
TK_Src_SrcB_LYN_Y	P60484	PTEN	P07948	LYN	Y27	L23F	23	Missense	distal	-4	no	1.661	1.959	EPSD	COSMIC	1.526	Up-regulation
TK_Src_SrcB_LYN_Y	P60484	PTEN	P07948	LYN	Y27	D24N	24	Missense	distal	-3	no	1.661	1.620	EPSD	COSMIC	1.526	Down-regulation
TK_Src_SrcB_LYN_Y	P60484	PTEN	P07948	LYN	Y27	Y27H	27	Missense	central	0	yes	1.661	0.000	EPSD	COSMIC	1.526	Loss
TK_Src_SrcB_LYN_Y	P60484	PTEN	P07948	LYN	Y27	L25S	25	Missense	proximal	-2	no	1.661	4.530	EPSD	COSMIC	1.526	Up-regulation
TK_Src_SrcB_LYN_Y	P60484	PTEN	P07948	LYN	Y27	I28M	28	Missense	proximal	1	no	1.661	1.541	EPSD	COSMIC	1.526	Down-regulation
TK_Src_SrcB_LYN_Y	P60484	PTEN	P07948	LYN	Y27	N31H	31	Missense	distal	4	no	1.661	1.394	EPSD	COSMIC	1.526	Loss
TK_Src_SrcB_LYN_Y	P60484	PTEN	P07948	LYN	Y27	G20V	20	Missense	distal	-7	no	1.661	1.672	EPSD	COSMIC	1.526	Up-regulation
TK_Src_SrcB_LYN_Y	P60484	PTEN	P07948	LYN	Y27	G20E	20	Missense	distal	-7	no	1.661	1.908	EPSD	COSMIC	1.526	Up-regulation
TK_Src_SrcB_LYN_Y	P60484	PTEN	P07948	LYN	Y27	P30S	30	Missense	distal	3	no	1.661	-0.683	EPSD	COSMIC	1.526	Loss
TK_Src_SrcB_LYN_Y	P60484	PTEN	P07948	LYN	Y27	T26P	26	Missense	proximal	-1	no	1.661	0.913	EPSD	COSMIC	1.526	Loss
TK_Src_SrcB_LYN_Y	P60484	PTEN	P07948	LYN	Y27	D22G	22	Missense	distal	-5	no	1.661	2.089	EPSD	COSMIC	1.526	Up-regulation
TK_Src_SrcB_LYN_Y	P60484	PTEN	P07948	LYN	Y27	D24Y	24	Missense	distal	-3	no	1.661	1.614	EPSD	COSMIC;CCLE	1.526	Down-regulation
TK_Src_SrcB_LYN_Y	P60484	PTEN	P07948	LYN	Y27	T26I	26	Missense	proximal	-1	no	1.661	1.261	EPSD	COSMIC	1.526	Loss
TK_Src_SrcB_LYN_Y	P60484	PTEN	P07948	LYN	Y27	A34D	34	Missense	distal	7	no	1.661	1.656	EPSD	COSMIC	1.526	Down-regulation
TK_Src_SrcB_LYN_Y	P60484	PTEN	P07948	LYN	Y27	G20R	20	Missense	distal	-7	no	1.661	1.601	EPSD	COSMIC	1.526	Down-regulation
TK_Src_SrcB_LYN_Y	P60484	PTEN	P07948	LYN	Y27	Y27S	27	Missense	central	0	yes	1.661	0.000	EPSD	COSMIC	1.526	Loss
TK_Src_SrcB_LYN_Y	P60484	PTEN	P07948	LYN	Y27	L23S	23	Missense	distal	-4	no	1.661	2.446	EPSD	COSMIC	1.526	Up-regulation
TK_Src_SrcB_LYN_Y	P60484	PTEN	P07948	LYN	Y27	D22Y	22	Missense	distal	-5	no	1.661	1.362	EPSD	COSMIC	1.526	Loss
TK_Src_SrcB_LYN_Y	P60484	PTEN	P07948	LYN	Y27	D22E	22	Missense	distal	-5	no	1.661	2.992	EPSD	COSMIC	1.526	Up-regulation
TK_Src_SrcB_LYN_Y	P60484	PTEN	P07948	LYN	Y27	T26A	26	Missense	proximal	-1	no	1.661	0.043	EPSD	COSMIC	1.526	Loss
TK_Src_SrcB_LYN_Y	P60484	PTEN	P07948	LYN	Y46	I50N	50	Missense	distal	4	no	2.264	2.411	EPSD	COSMIC	1.526	Up-regulation
TK_Src_SrcB_LYN_Y	P60484	PTEN	P07948	LYN	Y46	V45A	45	Missense	proximal	-1	no	2.264	1.910	EPSD	COSMIC	1.526	Down-regulation
TK_Src_SrcB_LYN_Y	P60484	PTEN	P07948	LYN	Y46	A39T	39	Missense	distal	-7	no	2.264	1.944	EPSD	COSMIC	1.526	Down-regulation
TK_Src_SrcB_LYN_Y	P60484	PTEN	P07948	LYN	Y46	V53G	53	Missense	distal	7	no	2.264	2.309	EPSD	COSMIC	1.526	Up-regulation
TK_Src_SrcB_LYN_Y	P60484	PTEN	P07948	LYN	Y46	Y46C	46	Missense	central	0	yes	2.264	0.000	EPSD	COSMIC;GDSC;CCLE	1.526	Loss
TK_Src_SrcB_LYN_Y	P60484	PTEN	P07948	LYN	Y46	L42R	42	Missense	distal	-4	no	2.264	1.434	EPSD	COSMIC;GDSC;CCLE	1.526	Loss
TK_Src_SrcB_LYN_Y	P60484	PTEN	P07948	LYN	Y46	N49I	49	Missense	distal	3	no	2.264	2.588	EPSD	COSMIC	1.526	Up-regulation
TK_Src_SrcB_LYN_Y	P60484	PTEN	P07948	LYN	Y46	V53A	53	Missense	distal	7	no	2.264	2.243	EPSD	COSMIC	1.526	Down-regulation
TK_Src_SrcB_LYN_Y	P60484	PTEN	P07948	LYN	Y46	R47G	47	Missense	proximal	1	no	2.264	2.220	EPSD	COSMIC;GDSC;CCLE	1.526	Down-regulation
TK_Src_SrcB_LYN_Y	P60484	PTEN	P07948	LYN	Y46	A39E	39	Missense	distal	-7	no	2.264	2.500	EPSD	COSMIC	1.526	Up-regulation
TK_Src_SrcB_LYN_Y	P60484	PTEN	P07948	LYN	Y46	D52N	52	Missense	distal	6	no	2.264	2.263	EPSD	COSMIC	1.526	Down-regulation
TK_Src_SrcB_LYN_Y	P60484	PTEN	P07948	LYN	Y46	D52G	52	Missense	distal	6	no	2.264	2.031	EPSD	COSMIC	1.526	Down-regulation
TK_Src_SrcB_LYN_Y	P60484	PTEN	P07948	LYN	Y46	L42F	42	Missense	distal	-4	no	2.264	2.562	EPSD	COSMIC	1.526	Up-regulation
TK_Src_SrcB_LYN_Y	P60484	PTEN	P07948	LYN	Y46	N48D	48	Missense	proximal	2	no	2.264	2.400	EPSD	COSMIC	1.526	Up-regulation
TK_Src_SrcB_LYN_Y	P60484	PTEN	P07948	LYN	Y46	R47S	47	Missense	proximal	1	no	2.264	2.568	EPSD	COSMIC	1.526	Up-regulation
TK_Src_SrcB_LYN_Y	P60484	PTEN	P07948	LYN	Y46	V45I	45	Missense	proximal	-1	no	2.264	3.128	EPSD	COSMIC	1.526	Up-regulation
TK_Src_SrcB_LYN_Y	P60484	PTEN	P07948	LYN	Y46	R41K	41	Missense	distal	-5	no	2.264	1.527	EPSD	COSMIC	1.526	Down-regulation
TK_Src_SrcB_LYN_Y	P60484	PTEN	P07948	LYN	Y46	L42H	42	Missense	distal	-4	no	2.264	2.457	EPSD	COSMIC	1.526	Up-regulation
TK_Src_SrcB_LYN_Y	P60484	PTEN	P07948	LYN	Y68	C71W	71	Missense	distal	3	no	0.181	1.640	EPSD	COSMIC	1.526	Gain
TK_Src_SrcB_LYN_Y	P60484	PTEN	P07948	LYN	Y68	E73K	73	Missense	distal	5	no	0.181	1.858	EPSD	COSMIC	1.526	Gain
TK_Src_SrcB_LYN_Y	P60484	PTEN	P07948	LYN	Y155	L152V	152	Missense	distal	-3	no	-0.138	1.693	EPSD	COSMIC	1.526	Gain
TK_Src_SrcB_LYN_Y	P60484	PTEN	P07948	LYN	Y178	L181Q	181	Missense	distal	3	no	4.329	2.357	EPSD	COSMIC	1.526	Down-regulation
TK_Src_SrcB_LYN_Y	P60484	PTEN	P07948	LYN	Y178	Y176F	176	Missense	proximal	-2	no	4.329	2.650	EPSD	COSMIC	1.526	Down-regulation
TK_Src_SrcB_LYN_Y	P60484	PTEN	P07948	LYN	Y178	Y174D	174	Missense	distal	-4	no	4.329	4.690	EPSD	COSMIC	1.526	Up-regulation
TK_Src_SrcB_LYN_Y	P60484	PTEN	P07948	LYN	Y178	Y174N	174	Missense	distal	-4	no	4.329	4.256	EPSD	COSMIC	1.526	Down-regulation
TK_Src_SrcB_LYN_Y	P60484	PTEN	P07948	LYN	Y178	R172W	172	Missense	distal	-6	no	4.329	4.068	EPSD	COSMIC	1.526	Down-regulation
TK_Src_SrcB_LYN_Y	P60484	PTEN	P07948	LYN	Y178	R173P	173	Missense	distal	-5	no	4.329	4.042	EPSD	COSMIC;GDSC;CCLE	1.526	Down-regulation
TK_Src_SrcB_LYN_Y	P60484	PTEN	P07948	LYN	Y178	L182F	182	Missense	distal	4	no	4.329	4.255	EPSD	COSMIC	1.526	Down-regulation
TK_Src_SrcB_LYN_Y	P60484	PTEN	P07948	LYN	Y178	H185Y	185	Missense	distal	7	no	4.329	4.249	EPSD	COSMIC	1.526	Down-regulation
TK_Src_SrcB_LYN_Y	P60484	PTEN	P07948	LYN	Y178	V175M	175	Missense	distal	-3	no	4.329	3.844	EPSD	COSMIC	1.526	Down-regulation
TK_Src_SrcB_LYN_Y	P60484	PTEN	P07948	LYN	Y178	N184I	184	Missense	distal	6	no	4.329	4.038	EPSD	COSMIC	1.526	Down-regulation
TK_Src_SrcB_LYN_Y	P60484	PTEN	P07948	LYN	Y178	Y178H	178	Missense	central	0	yes	4.329	0.000	EPSD	COSMIC	1.526	Loss
TK_Src_SrcB_LYN_Y	P60484	PTEN	P07948	LYN	Y178	L182V	182	Missense	distal	4	no	4.329	4.328	EPSD	COSMIC	1.526	Down-regulation
TK_Src_SrcB_LYN_Y	P60484	PTEN	P07948	LYN	Y178	Y177H	177	Missense	proximal	-1	no	4.329	4.531	EPSD	COSMIC	1.526	Up-regulation
TK_Src_SrcB_LYN_Y	P60484	PTEN	P07948	LYN	Y178	Q171P	171	Missense	distal	-7	no	4.329	4.467	EPSD	COSMIC	1.526	Up-regulation
TK_Src_SrcB_LYN_Y	P60484	PTEN	P07948	LYN	Y178	K183N	183	Missense	distal	5	no	4.329	3.645	EPSD	COSMIC	1.526	Down-regulation
TK_Src_SrcB_LYN_Y	P60484	PTEN	P07948	LYN	Y178	S179I	179	Missense	proximal	1	no	4.329	3.754	EPSD	COSMIC	1.526	Down-regulation
TK_Src_SrcB_LYN_Y	P60484	PTEN	P07948	LYN	Y178	Y176C	176	Missense	proximal	-2	no	4.329	0.511	EPSD	COSMIC	1.526	Loss
TK_Src_SrcB_LYN_Y	P60484	PTEN	P07948	LYN	Y178	Y178D	178	Missense	central	0	yes	4.329	0.000	EPSD	COSMIC	1.526	Loss
TK_Src_SrcB_LYN_Y	P60484	PTEN	P07948	LYN	Y178	V175A	175	Missense	distal	-3	no	4.329	3.368	EPSD	COSMIC	1.526	Down-regulation
TK_Src_SrcB_LYN_Y	P60484	PTEN	P07948	LYN	Y178	Y174C	174	Missense	distal	-4	no	4.329	1.194	EPSD	COSMIC	1.526	Loss
TK_Src_SrcB_LYN_Y	P60484	PTEN	P07948	LYN	Y178	Y178F	178	Missense	central	0	yes	4.329	0.000	EPSD	COSMIC	1.526	Loss
TK_Src_SrcB_LYN_Y	P60484	PTEN	P07948	LYN	Y178	Q171H	171	Missense	distal	-7	no	4.329	4.618	EPSD	COSMIC	1.526	Up-regulation
TK_Src_SrcB_LYN_Y	P60484	PTEN	P07948	LYN	Y178	R173S	173	Missense	distal	-5	no	4.329	3.807	EPSD	COSMIC	1.526	Down-regulation
TK_Src_SrcB_LYN_Y	P60484	PTEN	P07948	LYN	Y178	L181R	181	Missense	distal	3	no	4.329	3.539	EPSD	COSMIC	1.526	Down-regulation
TK_Src_SrcB_LYN_Y	P60484	PTEN	P07948	LYN	Y178	Y178N	178	Missense	central	0	yes	4.329	0.000	EPSD	COSMIC	1.526	Loss
TK_Src_SrcB_LYN_Y	P60484	PTEN	P07948	LYN	Y178	Y174H	174	Missense	distal	-4	no	4.329	3.444	EPSD	COSMIC	1.526	Down-regulation
TK_Src_SrcB_LYN_Y	P60484	PTEN	P07948	LYN	Y240	R234Q	234	Missense	distal	-6	no	1.505	1.727	PhosphoSitePlus	COSMIC	1.526	Gain
TK_Src_SrcB_LYN_Y	P60484	PTEN	P07948	LYN	Y240	F241V	241	Missense	proximal	1	no	1.505	1.745	PhosphoSitePlus	COSMIC	1.526	Gain
TK_Src_SrcB_LYN_Y	P60484	PTEN	P07948	LYN	Y240	F238L	238	Missense	proximal	-2	no	1.505	1.706	PhosphoSitePlus	COSMIC	1.526	Gain
TK_Src_SrcB_LYN_Y	P60484	PTEN	P07948	LYN	Y240	R233G	233	Missense	distal	-7	no	1.505	1.565	PhosphoSitePlus	COSMIC;CCLE	1.526	Gain
TK_Src_SrcB_LYN_Y	P60484	PTEN	P07948	LYN	Y240	F243L	243	Missense	distal	3	no	1.505	2.366	PhosphoSitePlus	COSMIC	1.526	Gain
TK_Src_SrcB_LYN_Y	P60484	PTEN	P07948	LYN	Y315	L318F	318	Missense	distal	3	no	3.455	2.594	EPSD	COSMIC	1.526	Down-regulation
TK_Src_SrcB_LYN_Y	P60484	PTEN	P07948	LYN	Y315	L320V	320	Missense	distal	5	no	3.455	2.291	EPSD	COSMIC	1.526	Down-regulation
TK_Src_SrcB_LYN_Y	P60484	PTEN	P07948	LYN	Y315	Y315H	315	Missense	central	0	yes	3.455	0.000	EPSD	COSMIC	1.526	Loss
TK_Src_SrcB_LYN_Y	P60484	PTEN	P07948	LYN	Y315	L318P	318	Missense	distal	3	no	3.455	4.105	EPSD	COSMIC	1.526	Up-regulation
TK_Src_SrcB_LYN_Y	P60484	PTEN	P07948	LYN	Y315	R308H	308	Missense	distal	-7	no	3.455	3.706	EPSD	COSMIC	1.526	Up-regulation
TK_Src_SrcB_LYN_Y	P60484	PTEN	P07948	LYN	Y315	V317G	317	Missense	proximal	2	no	3.455	3.485	EPSD	COSMIC	1.526	Up-regulation
TK_Src_SrcB_LYN_Y	P60484	PTEN	P07948	LYN	Y315	E314K	314	Missense	proximal	-1	no	3.455	2.777	EPSD	COSMIC	1.526	Down-regulation
TK_Src_SrcB_LYN_Y	P60484	PTEN	P07948	LYN	Y315	T321I	321	Missense	distal	6	no	3.455	3.334	EPSD	COSMIC	1.526	Down-regulation
TK_Src_SrcB_LYN_Y	P60484	PTEN	P07948	LYN	Y377	D375N	375	Missense	proximal	-2	no	3.487	3.421	EPSD	COSMIC	1.526	Down-regulation
TK_Src_SrcB_LYN_Y	P60484	PTEN	P07948	LYN	Y377	T383I	383	Missense	distal	6	no	3.487	3.367	EPSD	COSMIC	1.526	Down-regulation
TK_Src_SrcB_LYN_Y	P60484	PTEN	P07948	LYN	Y377	D384N	384	Missense	distal	7	no	3.487	3.507	EPSD	COSMIC	1.526	Up-regulation
TK_Src_SrcB_LYN_Y	P60484	PTEN	P07948	LYN	Y377	T382S	382	Missense	distal	5	no	3.487	2.766	EPSD	COSMIC	1.526	Down-regulation
TK_Src_SrcB_LYN_Y	P60484	PTEN	P07948	LYN	Y377	D384G	384	Missense	distal	7	no	3.487	3.559	EPSD	COSMIC	1.526	Up-regulation
TK_Src_SrcB_LYN_Y	P60484	PTEN	P07948	LYN	Y379	D375N	375	Missense	distal	-4	no	1.716	1.281	EPSD	COSMIC	1.526	Loss
TK_Src_SrcB_LYN_Y	P60484	PTEN	P07948	LYN	Y379	T383I	383	Missense	distal	4	no	1.716	1.450	EPSD	COSMIC	1.526	Loss
TK_Src_SrcB_LYN_Y	P60484	PTEN	P07948	LYN	Y379	D384N	384	Missense	distal	5	no	1.716	1.569	EPSD	COSMIC	1.526	Down-regulation
TK_Src_SrcB_LYN_Y	P60484	PTEN	P07948	LYN	Y379	T382S	382	Missense	distal	3	no	1.716	1.028	EPSD	COSMIC	1.526	Loss
TK_Src_SrcB_LYN_Y	P60484	PTEN	P07948	LYN	Y379	D384G	384	Missense	distal	5	no	1.716	2.371	EPSD	COSMIC	1.526	Up-regulation
TK_Src_SrcB_LYN_Y	P22681	CBL	P07948	LYN	Y141	R139T	139	Missense	proximal	-2	no	2.213	2.097	EPSD	COSMIC	1.526	Down-regulation
TK_Src_SrcB_LYN_Y	P22681	CBL	P07948	LYN	Y141	Y141C	141	Missense	central	0	yes	2.213	0.000	EPSD	COSMIC	1.526	Loss
TK_Src_SrcB_LYN_Y	P22681	CBL	P07948	LYN	Y337	R333M	333	Missense	distal	-4	no	0.912	1.957	EPSD	COSMIC	1.526	Gain
TK_Src_SrcB_LYN_Y	P22681	CBL	P07948	LYN	Y337	G335S	335	Missense	proximal	-2	no	0.912	1.889	EPSD	COSMIC	1.526	Gain
TK_Src_SrcB_LYN_Y	P22681	CBL	P07948	LYN	Y371	M374V	374	Missense	distal	3	no	2.726	2.467	PhosphoSitePlus	COSMIC	1.526	Down-regulation
TK_Src_SrcB_LYN_Y	P22681	CBL	P07948	LYN	Y371	Y371S	371	Missense	central	0	yes	2.726	0.000	PhosphoSitePlus	COSMIC	1.526	Loss
TK_Src_SrcB_LYN_Y	P22681	CBL	P07948	LYN	Y371	Y371N	371	Missense	central	0	yes	2.726	0.000	PhosphoSitePlus	COSMIC	1.526	Loss
TK_Src_SrcB_LYN_Y	P22681	CBL	P07948	LYN	Y371	Q367P	367	Missense	distal	-4	no	2.726	0.705	PhosphoSitePlus	COSMIC	1.526	Loss
TK_Src_SrcB_LYN_Y	P22681	CBL	P07948	LYN	Y371	Y368N	368	Missense	distal	-3	no	2.726	2.732	PhosphoSitePlus	COSMIC	1.526	Up-regulation
TK_Src_SrcB_LYN_Y	P22681	CBL	P07948	LYN	Y371	Y371C	371	Missense	central	0	yes	2.726	0.000	PhosphoSitePlus	COSMIC	1.526	Loss
TK_Src_SrcB_LYN_Y	P22681	CBL	P07948	LYN	Y371	Y371D	371	Missense	central	0	yes	2.726	0.000	PhosphoSitePlus	COSMIC	1.526	Loss
TK_Src_SrcB_LYN_Y	P22681	CBL	P07948	LYN	Y371	Q367R	367	Missense	distal	-4	no	2.726	0.386	PhosphoSitePlus	COSMIC	1.526	Loss
TK_Src_SrcB_LYN_Y	P22681	CBL	P07948	LYN	Y371	S376F	376	Missense	distal	5	no	2.726	3.102	PhosphoSitePlus	COSMIC	1.526	Up-regulation
TK_Src_SrcB_LYN_Y	P22681	CBL	P07948	LYN	Y371	L370F	370	Missense	proximal	-1	no	2.726	3.122	PhosphoSitePlus	COSMIC	1.526	Up-regulation
TK_Src_SrcB_LYN_Y	P22681	CBL	P07948	LYN	Y371	T377A	377	Missense	distal	6	no	2.726	2.732	PhosphoSitePlus	COSMIC	1.526	Up-regulation
TK_Src_SrcB_LYN_Y	P22681	CBL	P07948	LYN	Y371	E366D	366	Missense	distal	-5	no	2.726	1.394	PhosphoSitePlus	COSMIC	1.526	Loss
TK_Src_SrcB_LYN_Y	P22681	CBL	P07948	LYN	Y371	E366Q	366	Missense	distal	-5	no	2.726	1.551	PhosphoSitePlus	COSMIC	1.526	Down-regulation
TK_Src_SrcB_LYN_Y	P22681	CBL	P07948	LYN	Y371	G375P	375	Missense	distal	4	no	2.726	2.923	PhosphoSitePlus	COSMIC	1.526	Up-regulation
TK_Src_SrcB_LYN_Y	P22681	CBL	P07948	LYN	Y371	G375S	375	Missense	distal	4	no	2.726	2.739	PhosphoSitePlus	COSMIC	1.526	Up-regulation
TK_Src_SrcB_LYN_Y	P22681	CBL	P07948	LYN	Y674	A677V	677	Missense	distal	3	no	1.400	2.535	EPSD	COSMIC	1.526	Gain
TK_Src_SrcB_LYN_Y	P22681	CBL	P07948	LYN	Y674	A678T	678	Missense	distal	4	no	1.400	1.682	EPSD	COSMIC	1.526	Gain
TK_Src_SrcB_LYN_Y	P22681	CBL	P07948	LYN	Y700	M701V	701	Missense	proximal	1	no	0.737	1.651	EPSD	COSMIC	1.526	Gain
TK_Src_SrcB_LYN_Y	P22681	CBL	P07948	LYN	Y700	S705C	705	Missense	distal	5	no	0.737	2.859	EPSD	COSMIC	1.526	Gain
TK_Src_SrcB_LYN_Y	P14317	HCLS1	P07948	LYN	Y83	G85D	85	Missense	proximal	2	no	1.814	2.061	EPSD	COSMIC	1.526	Up-regulation
TK_Src_SrcB_LYN_Y	P14317	HCLS1	P07948	LYN	Y83	G88E	88	Missense	distal	5	no	1.814	0.020	EPSD	COSMIC	1.526	Loss
TK_Src_SrcB_LYN_Y	P14317	HCLS1	P07948	LYN	Y83	K78R	78	Missense	distal	-5	no	1.814	2.551	EPSD	COSMIC	1.526	Up-regulation
TK_Src_SrcB_LYN_Y	P14317	HCLS1	P07948	LYN	Y83	G84E	84	Missense	proximal	1	no	1.814	2.677	EPSD	COSMIC	1.526	Up-regulation
TK_Src_SrcB_LYN_Y	P14317	HCLS1	P07948	LYN	Y190	G193C	193	Missense	distal	3	no	2.670	4.292	EPSD	COSMIC	1.526	Up-regulation
TK_Src_SrcB_LYN_Y	P14317	HCLS1	P07948	LYN	Y190	G193S	193	Missense	distal	3	no	2.670	2.973	EPSD	COSMIC	1.526	Up-regulation
TK_Src_SrcB_LYN_Y	P14317	HCLS1	P07948	LYN	Y222	E216D	216	Missense	distal	-6	no	5.208	4.984	PhosphoSitePlus	COSMIC	1.526	Down-regulation
TK_Src_SrcB_LYN_Y	P14317	HCLS1	P07948	LYN	Y222	A217V	217	Missense	distal	-5	no	5.208	6.376	PhosphoSitePlus	COSMIC	1.526	Up-regulation
TK_Src_SrcB_LYN_Y	P14317	HCLS1	P07948	LYN	Y222	T226A	226	Missense	distal	4	no	5.208	4.926	PhosphoSitePlus	COSMIC	1.526	Down-regulation
TK_Src_SrcB_LYN_Y	P14317	HCLS1	P07948	LYN	Y360	Y360S	360	Missense	central	0	yes	1.772	0.000	EPSD	COSMIC	1.526	Loss
TK_Src_SrcB_LYN_Y	P14317	HCLS1	P07948	LYN	Y360	E367Q	367	Missense	distal	7	no	1.772	1.734	EPSD	COSMIC	1.526	Down-regulation
TK_Src_SrcB_LYN_Y	P14317	HCLS1	P07948	LYN	Y360	E355K	355	Missense	distal	-5	no	1.772	0.946	EPSD	COSMIC	1.526	Loss
TK_Src_SrcB_LYN_Y	P14317	HCLS1	P07948	LYN	Y360	E365A	365	Missense	distal	5	no	1.772	2.469	EPSD	COSMIC	1.526	Up-regulation
TK_Src_SrcB_LYN_Y	P14317	HCLS1	P07948	LYN	Y360	E361G	361	Missense	proximal	1	no	1.772	0.909	EPSD	COSMIC	1.526	Loss
TK_Src_SrcB_LYN_Y	P14317	HCLS1	P07948	LYN	Y360	A362P	362	Missense	proximal	2	no	1.772	1.505	EPSD	COSMIC;GDSC	1.526	Loss
TK_Src_SrcB_LYN_Y	P14317	HCLS1	P07948	LYN	Y360	V354L	354	Missense	distal	-6	no	1.772	1.131	EPSD	COSMIC	1.526	Loss
TK_Src_SrcB_LYN_Y	P14317	HCLS1	P07948	LYN	Y360	E356K	356	Missense	distal	-4	no	1.772	1.399	EPSD	COSMIC	1.526	Loss
TK_Src_SrcB_LYN_Y	P14317	HCLS1	P07948	LYN	Y360	P358S	358	Missense	proximal	-2	no	1.772	2.401	EPSD	COSMIC	1.526	Up-regulation
TK_Src_SrcB_LYN_Y	P14317	HCLS1	P07948	LYN	Y378	E373A	373	Missense	distal	-5	no	4.497	2.992	EPSD	COSMIC;CCLE	1.526	Down-regulation
TK_Src_SrcB_LYN_Y	P14317	HCLS1	P07948	LYN	Y378	M384I	384	Missense	distal	6	no	4.497	4.281	EPSD	COSMIC	1.526	Down-regulation
TK_Src_SrcB_LYN_Y	P14317	HCLS1	P07948	LYN	Y378	E382A	382	Missense	distal	4	no	4.497	4.345	EPSD	COSMIC	1.526	Down-regulation
TK_Src_SrcB_LYN_Y	P14317	HCLS1	P07948	LYN	Y397	D396E	396	Missense	proximal	-1	no	4.274	4.630	EPSD	COSMIC	1.526	Up-regulation
TK_Src_SrcB_LYN_Y	P14317	HCLS1	P07948	LYN	Y397	E392K	392	Missense	distal	-5	no	4.274	3.448	EPSD	COSMIC	1.526	Down-regulation
TK_Src_SrcB_LYN_Y	P14317	HCLS1	P07948	LYN	Y397	E404Q	404	Missense	distal	7	no	4.274	4.236	EPSD	COSMIC;CCLE	1.526	Down-regulation
TK_Src_SrcB_LYN_Y	P14317	HCLS1	P07948	LYN	Y397	G395E	395	Missense	proximal	-2	no	4.274	4.600	EPSD	COSMIC	1.526	Up-regulation
TK_Src_SrcB_LYN_Y	Q8N6F7	GCSAM	P07948	LYN	Y80	Q78H	78	Missense	proximal	-2	no	2.509	3.094	EPSD	COSMIC	1.526	Up-regulation
TK_Src_SrcB_LYN_Y	Q8N6F7	GCSAM	P07948	LYN	Y80	E83K	83	Missense	distal	3	no	2.509	1.207	EPSD	COSMIC	1.526	Loss
TK_Src_SrcB_LYN_Y	Q8N6F7	GCSAM	P07948	LYN	Y80	D74G	74	Missense	distal	-6	no	2.509	2.190	EPSD	COSMIC	1.526	Down-regulation
TK_Src_SrcB_LYN_Y	Q8N6F7	GCSAM	P07948	LYN	Y107	N101D	101	Missense	distal	-6	no	4.450	4.424	EPSD;PhosphoSitePlus	COSMIC	1.526	Down-regulation
TK_Src_SrcB_LYN_Y	Q8N6F7	GCSAM	P07948	LYN	Y107	G100W	100	Missense	distal	-7	no	4.450	4.503	EPSD;PhosphoSitePlus	COSMIC	1.526	Up-regulation
TK_Src_SrcB_LYN_Y	Q8N6F7	GCSAM	P07948	LYN	Y128	S129L	129	Missense	proximal	1	no	3.885	2.901	PhosphoSitePlus;EPSD	COSMIC	1.526	Down-regulation
TK_Src_SrcB_LYN_Y	O14920	IKBKB	P07948	LYN	Y188	L194Q	194	Missense	distal	6	no	2.113	2.175	PhosphoSitePlus;EPSD	COSMIC	1.526	Up-regulation
TK_Src_SrcB_LYN_Y	O14920	IKBKB	P07948	LYN	Y199	D204N	204	Missense	distal	5	no	2.659	2.512	EPSD;PhosphoSitePlus	COSMIC	1.526	Down-regulation
TK_Src_SrcB_LYN_Y	O14920	IKBKB	P07948	LYN	Y199	L194Q	194	Missense	distal	-5	no	2.659	2.792	EPSD;PhosphoSitePlus	COSMIC	1.526	Up-regulation
TK_Src_SrcB_LYN_Y	O14920	IKBKB	P07948	LYN	Y199	V201I	201	Missense	proximal	2	no	2.659	2.202	EPSD;PhosphoSitePlus	COSMIC	1.526	Down-regulation
TK_Src_SrcB_LYN_Y	Q9H792	PEAK1	P07948	LYN	Y387	E388K	388	Missense	proximal	1	no	1.850	0.863	EPSD	COSMIC	1.526	Loss
TK_Src_SrcB_LYN_Y	Q9H792	PEAK1	P07948	LYN	Y616	H611Q	611	Missense	distal	-5	no	2.500	2.093	EPSD	COSMIC;GDSC;CCLE	1.526	Down-regulation
TK_Src_SrcB_LYN_Y	Q9H792	PEAK1	P07948	LYN	Y880	R874L	874	Missense	distal	-6	no	2.188	1.935	EPSD	COSMIC	1.526	Down-regulation
TK_Src_SrcB_LYN_Y	Q9H792	PEAK1	P07948	LYN	Y880	N884S	884	Missense	distal	4	no	2.188	2.058	EPSD	COSMIC	1.526	Down-regulation
TK_Src_SrcB_LYN_Y	Q9H792	PEAK1	P07948	LYN	Y1215	R1220K	1220	Missense	distal	5	no	2.268	2.884	EPSD	COSMIC	1.526	Up-regulation
TK_Src_SrcB_LYN_Y	Q9H792	PEAK1	P07948	LYN	Y1372	L1375F	1375	Missense	distal	3	no	2.096	1.235	EPSD	COSMIC;GDSC;CCLE	1.526	Loss
TK_Src_SrcB_LYN_Y	Q9H792	PEAK1	P07948	LYN	Y1620	R1627H	1627	Missense	distal	7	no	3.096	3.146	EPSD	COSMIC	1.526	Up-regulation
TK_Src_SrcB_LYN_Y	P11802	CDK4	P07948	LYN	Y17	A10D	10	Missense	distal	-7	no	3.291	3.422	PhosphoSitePlus	COSMIC	1.526	Up-regulation
TK_Src_SrcB_LYN_Y	P11802	CDK4	P07948	LYN	Y17	K22R	22	Missense	distal	5	no	3.291	2.675	PhosphoSitePlus	COSMIC	1.526	Down-regulation
TK_Src_SrcB_LYN_Y	P11802	CDK4	P07948	LYN	Y17	A23T	23	Missense	distal	6	no	3.291	3.284	PhosphoSitePlus	COSMIC	1.526	Down-regulation
TK_Src_SrcB_LYN_Y	P11802	CDK4	P07948	LYN	Y165	Q168E	168	Missense	distal	3	no	0.483	2.300	EPSD	COSMIC	1.526	Gain
TK_Src_SrcB_LYN_Y	P42768	WAS	P07948	LYN	Y54	G60V	60	Missense	distal	6	no	2.706	2.814	EPSD	COSMIC	1.526	Up-regulation
TK_Src_SrcB_LYN_Y	P42768	WAS	P07948	LYN	Y54	P59L	59	Missense	distal	5	no	2.706	3.372	EPSD	COSMIC;GDSC;CCLE	1.526	Up-regulation
TK_Src_SrcB_LYN_Y	P42768	WAS	P07948	LYN	Y102	T109P	109	Missense	distal	7	no	2.571	2.576	EPSD	COSMIC	1.526	Up-regulation
TK_Src_SrcB_LYN_Y	P42768	WAS	P07948	LYN	Y102	E100K	100	Missense	proximal	-2	no	2.571	1.858	EPSD	COSMIC	1.526	Down-regulation
TK_Src_SrcB_LYN_Y	P42768	WAS	P07948	LYN	Y102	W97C	97	Missense	distal	-5	no	2.571	2.427	EPSD	COSMIC	1.526	Down-regulation
TK_Src_SrcB_LYN_Y	P42768	WAS	P07948	LYN	Y212	T208M	208	Missense	distal	-4	no	3.424	2.572	EPSD	COSMIC	1.526	Down-regulation
TK_Src_SrcB_LYN_Y	P42768	WAS	P07948	LYN	Y212	R213L	213	Missense	proximal	1	no	3.424	2.745	EPSD	COSMIC	1.526	Down-regulation
TK_Src_SrcB_LYN_Y	P33993	MCM7	P07948	LYN	Y126	R120Q	120	Missense	distal	-6	no	1.746	1.968	EPSD	COSMIC	1.526	Up-regulation
TK_Src_SrcB_LYN_Y	P33993	MCM7	P07948	LYN	Y600	T599I	599	Missense	proximal	-1	no	3.399	2.999	PhosphoSitePlus	COSMIC	1.526	Down-regulation
TK_Src_SrcB_LYN_Y	P33993	MCM7	P07948	LYN	Y600	T599P	599	Missense	proximal	-1	no	3.399	2.651	PhosphoSitePlus	COSMIC	1.526	Down-regulation
TK_Src_SrcB_LYN_Y	P33993	MCM7	P07948	LYN	Y600	R604W	604	Missense	distal	4	no	3.399	3.376	PhosphoSitePlus	COSMIC	1.526	Down-regulation
TK_Src_SrcB_LYN_Y	Q9UN19	DAPP1	P07948	LYN	Y139	S137F	137	Missense	proximal	-2	no	8.133	5.064	PhosphoSitePlus	COSMIC	1.526	Down-regulation
TK_Src_SrcB_LYN_Y	P35354	PTGS2	P07948	LYN	Y116	D111E	111	Missense	distal	-5	no	1.193	2.525	EPSD	COSMIC	1.526	Gain
TK_Src_SrcB_LYN_Y	P35354	PTGS2	P07948	LYN	Y120	D119G	119	Missense	proximal	-1	no	2.017	0.548	PhosphoSitePlus	COSMIC	1.526	Loss
TK_Src_SrcB_LYN_Y	P35354	PTGS2	P07948	LYN	Y120	Y116C	116	Missense	distal	-4	no	2.017	-1.118	PhosphoSitePlus	COSMIC;GDSC;CCLE	1.526	Loss
TK_Src_SrcB_LYN_Y	P35354	PTGS2	P07948	LYN	Y248	Y248H	248	Missense	central	0	yes	2.244	0.000	EPSD	COSMIC;GDSC;CCLE	1.526	Loss
TK_Src_SrcB_LYN_Y	P35354	PTGS2	P07948	LYN	Y248	E246D	246	Missense	proximal	-2	no	2.244	2.417	EPSD	COSMIC	1.526	Up-regulation
TK_Src_SrcB_LYN_Y	P35354	PTGS2	P07948	LYN	Y248	D244G	244	Missense	distal	-4	no	2.244	0.934	EPSD	COSMIC	1.526	Loss
TK_Src_SrcB_LYN_Y	P35354	PTGS2	P07948	LYN	Y248	I242M	242	Missense	distal	-6	no	2.244	2.654	EPSD	COSMIC	1.526	Up-regulation
TK_Src_SrcB_LYN_Y	Q12972	PPP1R8	P07948	LYN	Y264	G265R	265	Missense	proximal	1	no	4.182	4.226	EPSD	COSMIC;GDSC;CCLE	1.526	Up-regulation
TK_Src_SrcB_LYN_Y	Q12972	PPP1R8	P07948	LYN	Y264	G261R	261	Missense	distal	-3	no	4.182	3.940	EPSD	COSMIC	1.526	Down-regulation
TK_Src_SrcB_LYN_Y	Q12972	PPP1R8	P07948	LYN	Y264	P269L	269	Missense	distal	5	no	4.182	4.848	EPSD	COSMIC	1.526	Up-regulation
TK_Src_SrcB_LYN_Y	Q12972	PPP1R8	P07948	LYN	Y264	P269H	269	Missense	distal	5	no	4.182	3.702	EPSD	COSMIC	1.526	Down-regulation
AGC_RSK_RSKp90_RPS6KA3_ST	Q14934	NFATC4	P51812	RPS6KA3	S73	P75H	75	Missense	proximal	2	no	1.827	1.804	EPSD	COSMIC	1.803	Down-regulation
AGC_RSK_RSKp90_RPS6KA3_ST	Q14934	NFATC4	P51812	RPS6KA3	S73	P66H	66	Missense	distal	-7	no	1.827	1.833	EPSD	COSMIC	1.803	Up-regulation
AGC_RSK_RSKp90_RPS6KA3_ST	Q14934	NFATC4	P51812	RPS6KA3	S73	P66A	66	Missense	distal	-7	no	1.827	1.822	EPSD	COSMIC	1.803	Down-regulation
AGC_RSK_RSKp90_RPS6KA3_ST	Q14934	NFATC4	P51812	RPS6KA3	S73	P69L	69	Missense	distal	-4	no	1.827	1.790	EPSD	COSMIC	1.803	Loss
AGC_RSK_RSKp90_RPS6KA3_ST	Q14934	NFATC4	P51812	RPS6KA3	S73	R77Q	77	Missense	distal	4	no	1.827	1.861	EPSD	COSMIC	1.803	Up-regulation
AGC_RSK_RSKp90_RPS6KA3_ST	Q14934	NFATC4	P51812	RPS6KA3	S73	P78A	78	Missense	distal	5	no	1.827	1.813	EPSD	COSMIC	1.803	Down-regulation
AGC_RSK_RSKp90_RPS6KA3_ST	Q14934	NFATC4	P51812	RPS6KA3	S73	S73L	73	Missense	central	0	yes	1.827	0.000	EPSD	COSMIC	1.803	Loss
AGC_RSK_RSKp90_RPS6KA3_ST	Q14934	NFATC4	P51812	RPS6KA3	S120	P125H	125	Missense	distal	5	no	3.451	3.472	EPSD	COSMIC	1.803	Up-regulation
AGC_RSK_RSKp90_RPS6KA3_ST	Q14934	NFATC4	P51812	RPS6KA3	S120	S122C	122	Missense	proximal	2	no	3.451	3.350	EPSD	COSMIC	1.803	Down-regulation
AGC_RSK_RSKp90_RPS6KA3_ST	Q14934	NFATC4	P51812	RPS6KA3	S120	S120Y	120	Missense	central	0	yes	3.451	0.000	EPSD	COSMIC	1.803	Loss
AGC_RSK_RSKp90_RPS6KA3_ST	Q14934	NFATC4	P51812	RPS6KA3	S120	P123S	123	Missense	distal	3	no	3.451	3.446	EPSD	COSMIC	1.803	Down-regulation
AGC_RSK_RSKp90_RPS6KA3_ST	Q14934	NFATC4	P51812	RPS6KA3	S120	P125Q	125	Missense	distal	5	no	3.451	3.446	EPSD	COSMIC	1.803	Down-regulation
AGC_RSK_RSKp90_RPS6KA3_ST	Q14934	NFATC4	P51812	RPS6KA3	S120	P127L	127	Missense	distal	7	no	3.451	3.469	EPSD	COSMIC	1.803	Up-regulation
AGC_RSK_RSKp90_RPS6KA3_ST	Q14934	NFATC4	P51812	RPS6KA3	S120	T124M	124	Missense	distal	4	no	3.451	3.423	EPSD	COSMIC	1.803	Down-regulation
AGC_RSK_RSKp90_RPS6KA3_ST	Q14934	NFATC4	P51812	RPS6KA3	S168	G163R	163	Missense	distal	-5	no	1.542	1.910	EPSD	COSMIC	1.803	Gain
AGC_RSK_RSKp90_RPS6KA3_ST	Q14934	NFATC4	P51812	RPS6KA3	S217	R219I	219	Missense	proximal	2	no	1.806	1.703	EPSD	COSMIC	1.803	Loss
AGC_RSK_RSKp90_RPS6KA3_ST	Q14934	NFATC4	P51812	RPS6KA3	S217	S217L	217	Missense	central	0	yes	1.806	0.000	EPSD	COSMIC;CCLE	1.803	Loss
AGC_RSK_RSKp90_RPS6KA3_ST	Q14934	NFATC4	P51812	RPS6KA3	S217	R219Q	219	Missense	proximal	2	no	1.806	1.724	EPSD	COSMIC	1.803	Loss
AGC_RSK_RSKp90_RPS6KA3_ST	Q14934	NFATC4	P51812	RPS6KA3	S217	P216L	216	Missense	proximal	-1	no	1.806	1.791	EPSD	COSMIC	1.803	Loss
AGC_RSK_RSKp90_RPS6KA3_ST	Q14934	NFATC4	P51812	RPS6KA3	S217	P214Q	214	Missense	distal	-3	no	1.806	1.414	EPSD	COSMIC	1.803	Loss
AGC_RSK_RSKp90_RPS6KA3_ST	Q14934	NFATC4	P51812	RPS6KA3	S217	P224T	224	Missense	distal	7	no	1.806	1.827	EPSD	COSMIC	1.803	Up-regulation
AGC_RSK_RSKp90_RPS6KA3_ST	Q14934	NFATC4	P51812	RPS6KA3	S217	R223W	223	Missense	distal	6	no	1.806	1.738	EPSD	COSMIC	1.803	Loss
AGC_RSK_RSKp90_RPS6KA3_ST	Q14934	NFATC4	P51812	RPS6KA3	S221	R219I	219	Missense	proximal	-2	no	2.028	1.484	EPSD	COSMIC	1.803	Loss
AGC_RSK_RSKp90_RPS6KA3_ST	Q14934	NFATC4	P51812	RPS6KA3	S221	P227Q	227	Missense	distal	6	no	2.028	2.025	EPSD	COSMIC	1.803	Down-regulation
AGC_RSK_RSKp90_RPS6KA3_ST	Q14934	NFATC4	P51812	RPS6KA3	S221	P227H	227	Missense	distal	6	no	2.028	2.014	EPSD	COSMIC	1.803	Down-regulation
AGC_RSK_RSKp90_RPS6KA3_ST	Q14934	NFATC4	P51812	RPS6KA3	S221	E228K	228	Missense	distal	7	no	2.028	2.014	EPSD	COSMIC	1.803	Down-regulation
AGC_RSK_RSKp90_RPS6KA3_ST	Q14934	NFATC4	P51812	RPS6KA3	S221	S217L	217	Missense	distal	-4	no	2.028	1.936	EPSD	COSMIC;CCLE	1.803	Down-regulation
AGC_RSK_RSKp90_RPS6KA3_ST	Q14934	NFATC4	P51812	RPS6KA3	S221	R219Q	219	Missense	proximal	-2	no	2.028	1.503	EPSD	COSMIC	1.803	Loss
AGC_RSK_RSKp90_RPS6KA3_ST	Q14934	NFATC4	P51812	RPS6KA3	S221	P216L	216	Missense	distal	-5	no	2.028	2.006	EPSD	COSMIC	1.803	Down-regulation
AGC_RSK_RSKp90_RPS6KA3_ST	Q14934	NFATC4	P51812	RPS6KA3	S221	P224T	224	Missense	distal	3	no	2.028	2.032	EPSD	COSMIC	1.803	Up-regulation
AGC_RSK_RSKp90_RPS6KA3_ST	Q14934	NFATC4	P51812	RPS6KA3	S221	R223W	223	Missense	proximal	2	no	2.028	1.925	EPSD	COSMIC	1.803	Down-regulation
AGC_RSK_RSKp90_RPS6KA3_ST	Q14934	NFATC4	P51812	RPS6KA3	S221	T226S	226	Missense	distal	5	no	2.028	1.955	EPSD	COSMIC	1.803	Down-regulation
AGC_RSK_RSKp90_RPS6KA3_ST	Q14934	NFATC4	P51812	RPS6KA3	T226	R219I	219	Missense	distal	-7	no	2.154	2.180	EPSD	COSMIC	1.803	Up-regulation
AGC_RSK_RSKp90_RPS6KA3_ST	Q14934	NFATC4	P51812	RPS6KA3	T226	P227Q	227	Missense	proximal	1	no	2.154	2.146	EPSD	COSMIC	1.803	Down-regulation
AGC_RSK_RSKp90_RPS6KA3_ST	Q14934	NFATC4	P51812	RPS6KA3	T226	P227H	227	Missense	proximal	1	no	2.154	2.166	EPSD	COSMIC	1.803	Up-regulation
AGC_RSK_RSKp90_RPS6KA3_ST	Q14934	NFATC4	P51812	RPS6KA3	T226	E228K	228	Missense	proximal	2	no	2.154	2.179	EPSD	COSMIC	1.803	Up-regulation
AGC_RSK_RSKp90_RPS6KA3_ST	Q14934	NFATC4	P51812	RPS6KA3	T226	R219Q	219	Missense	distal	-7	no	2.154	2.174	EPSD	COSMIC	1.803	Up-regulation
AGC_RSK_RSKp90_RPS6KA3_ST	Q14934	NFATC4	P51812	RPS6KA3	T226	P224T	224	Missense	proximal	-2	no	2.154	2.073	EPSD	COSMIC	1.803	Down-regulation
AGC_RSK_RSKp90_RPS6KA3_ST	Q14934	NFATC4	P51812	RPS6KA3	T226	R223W	223	Missense	distal	-3	no	2.154	-0.388	EPSD	COSMIC	1.803	Loss
AGC_RSK_RSKp90_RPS6KA3_ST	Q14934	NFATC4	P51812	RPS6KA3	T226	W231S	231	Missense	distal	5	no	2.154	2.095	EPSD	COSMIC	1.803	Down-regulation
AGC_RSK_RSKp90_RPS6KA3_ST	Q14934	NFATC4	P51812	RPS6KA3	S246	P253L	253	Missense	distal	7	no	1.857	1.875	EPSD	COSMIC	1.803	Up-regulation
AGC_RSK_RSKp90_RPS6KA3_ST	Q14934	NFATC4	P51812	RPS6KA3	S246	R241L	241	Missense	distal	-5	no	1.857	1.511	EPSD	COSMIC	1.803	Loss
AGC_RSK_RSKp90_RPS6KA3_ST	Q14934	NFATC4	P51812	RPS6KA3	S246	R241Q	241	Missense	distal	-5	no	1.857	1.494	EPSD	COSMIC	1.803	Loss
AGC_RSK_RSKp90_RPS6KA3_ST	Q14934	NFATC4	P51812	RPS6KA3	S264	P257S	257	Missense	distal	-7	no	3.343	3.333	EPSD	COSMIC	1.803	Down-regulation
AGC_RSK_RSKp90_RPS6KA3_ST	Q14934	NFATC4	P51812	RPS6KA3	S264	R261W	261	Missense	distal	-3	no	3.343	0.801	EPSD	COSMIC	1.803	Loss
AGC_RSK_RSKp90_RPS6KA3_ST	Q14934	NFATC4	P51812	RPS6KA3	S264	P260Q	260	Missense	distal	-4	no	3.343	3.330	EPSD	COSMIC	1.803	Down-regulation
AGC_RSK_RSKp90_RPS6KA3_ST	Q14934	NFATC4	P51812	RPS6KA3	S264	R261Q	261	Missense	distal	-3	no	3.343	0.837	EPSD	COSMIC	1.803	Loss
AGC_RSK_RSKp90_RPS6KA3_ST	Q14934	NFATC4	P51812	RPS6KA3	S264	P265L	265	Missense	proximal	1	no	3.343	3.363	EPSD	COSMIC	1.803	Up-regulation
AGC_RSK_RSKp90_RPS6KA3_ST	Q14934	NFATC4	P51812	RPS6KA3	S264	Y271H	271	Missense	distal	7	no	3.343	3.336	EPSD	COSMIC	1.803	Down-regulation
AGC_RSK_RSKp90_RPS6KA3_ST	Q14934	NFATC4	P51812	RPS6KA3	S264	R269Q	269	Missense	distal	5	no	3.343	3.410	EPSD	COSMIC	1.803	Up-regulation
AGC_RSK_RSKp90_RPS6KA3_ST	Q14934	NFATC4	P51812	RPS6KA3	S264	R269W	269	Missense	distal	5	no	3.343	3.435	EPSD	COSMIC	1.803	Up-regulation
AGC_RSK_RSKp90_RPS6KA3_ST	Q14934	NFATC4	P51812	RPS6KA3	S264	R270H	270	Missense	distal	6	no	3.343	3.276	EPSD	COSMIC	1.803	Down-regulation
AGC_RSK_RSKp90_RPS6KA3_ST	Q14934	NFATC4	P51812	RPS6KA3	S264	R270C	270	Missense	distal	6	no	3.343	3.272	EPSD	COSMIC	1.803	Down-regulation
AGC_RSK_RSKp90_RPS6KA3_ST	Q14934	NFATC4	P51812	RPS6KA3	S264	S259F	259	Missense	distal	-5	no	3.343	3.210	EPSD	COSMIC	1.803	Down-regulation
AGC_RSK_RSKp90_RPS6KA3_ST	Q14934	NFATC4	P51812	RPS6KA3	S272	P277Q	277	Missense	distal	5	no	4.134	4.130	EPSD	COSMIC	1.803	Down-regulation
AGC_RSK_RSKp90_RPS6KA3_ST	Q14934	NFATC4	P51812	RPS6KA3	S272	S272F	272	Missense	central	0	yes	4.134	0.000	EPSD	COSMIC	1.803	Loss
AGC_RSK_RSKp90_RPS6KA3_ST	Q14934	NFATC4	P51812	RPS6KA3	S272	G275S	275	Missense	distal	3	no	4.134	4.127	EPSD	COSMIC	1.803	Down-regulation
AGC_RSK_RSKp90_RPS6KA3_ST	Q14934	NFATC4	P51812	RPS6KA3	S272	S273L	273	Missense	proximal	1	no	4.134	4.193	EPSD	COSMIC	1.803	Up-regulation
AGC_RSK_RSKp90_RPS6KA3_ST	Q14934	NFATC4	P51812	RPS6KA3	S272	P265L	265	Missense	distal	-7	no	4.134	4.143	EPSD	COSMIC	1.803	Up-regulation
AGC_RSK_RSKp90_RPS6KA3_ST	Q14934	NFATC4	P51812	RPS6KA3	S272	Y271H	271	Missense	proximal	-1	no	4.134	4.140	EPSD	COSMIC	1.803	Up-regulation
AGC_RSK_RSKp90_RPS6KA3_ST	Q14934	NFATC4	P51812	RPS6KA3	S272	R269Q	269	Missense	distal	-3	no	4.134	1.628	EPSD	COSMIC	1.803	Loss
AGC_RSK_RSKp90_RPS6KA3_ST	Q14934	NFATC4	P51812	RPS6KA3	S272	S272P	272	Missense	central	0	yes	4.134	0.000	EPSD	COSMIC	1.803	Loss
AGC_RSK_RSKp90_RPS6KA3_ST	Q14934	NFATC4	P51812	RPS6KA3	S272	R269W	269	Missense	distal	-3	no	4.134	1.592	EPSD	COSMIC	1.803	Loss
AGC_RSK_RSKp90_RPS6KA3_ST	Q14934	NFATC4	P51812	RPS6KA3	S272	R270H	270	Missense	proximal	-2	no	4.134	3.578	EPSD	COSMIC	1.803	Down-regulation
AGC_RSK_RSKp90_RPS6KA3_ST	Q14934	NFATC4	P51812	RPS6KA3	S272	R270C	270	Missense	proximal	-2	no	4.134	3.553	EPSD	COSMIC	1.803	Down-regulation
AGC_RSK_RSKp90_RPS6KA3_ST	Q14934	NFATC4	P51812	RPS6KA3	S272	S274L	274	Missense	proximal	2	no	4.134	4.028	EPSD	COSMIC	1.803	Down-regulation
AGC_RSK_RSKp90_RPS6KA3_ST	Q14934	NFATC4	P51812	RPS6KA3	S273	P277Q	277	Missense	distal	4	no	3.758	3.756	EPSD	COSMIC	1.803	Down-regulation
AGC_RSK_RSKp90_RPS6KA3_ST	Q14934	NFATC4	P51812	RPS6KA3	S273	S272F	272	Missense	proximal	-1	no	3.758	3.698	EPSD	COSMIC	1.803	Down-regulation
AGC_RSK_RSKp90_RPS6KA3_ST	Q14934	NFATC4	P51812	RPS6KA3	S273	G275S	275	Missense	proximal	2	no	3.758	3.843	EPSD	COSMIC	1.803	Up-regulation
AGC_RSK_RSKp90_RPS6KA3_ST	Q14934	NFATC4	P51812	RPS6KA3	S273	S273L	273	Missense	central	0	yes	3.758	0.000	EPSD	COSMIC	1.803	Loss
AGC_RSK_RSKp90_RPS6KA3_ST	Q14934	NFATC4	P51812	RPS6KA3	S273	Y271H	271	Missense	proximal	-2	no	3.758	3.770	EPSD	COSMIC	1.803	Up-regulation
AGC_RSK_RSKp90_RPS6KA3_ST	Q14934	NFATC4	P51812	RPS6KA3	S273	R269Q	269	Missense	distal	-4	no	3.758	3.592	EPSD	COSMIC	1.803	Down-regulation
AGC_RSK_RSKp90_RPS6KA3_ST	Q14934	NFATC4	P51812	RPS6KA3	S273	S272P	272	Missense	proximal	-1	no	3.758	3.732	EPSD	COSMIC	1.803	Down-regulation
AGC_RSK_RSKp90_RPS6KA3_ST	Q14934	NFATC4	P51812	RPS6KA3	S273	R269W	269	Missense	distal	-4	no	3.758	3.568	EPSD	COSMIC	1.803	Down-regulation
AGC_RSK_RSKp90_RPS6KA3_ST	Q14934	NFATC4	P51812	RPS6KA3	S273	R270H	270	Missense	distal	-3	no	3.758	1.220	EPSD	COSMIC	1.803	Loss
AGC_RSK_RSKp90_RPS6KA3_ST	Q14934	NFATC4	P51812	RPS6KA3	S273	R270C	270	Missense	distal	-3	no	3.758	1.147	EPSD	COSMIC	1.803	Loss
AGC_RSK_RSKp90_RPS6KA3_ST	Q14934	NFATC4	P51812	RPS6KA3	S273	S274L	274	Missense	proximal	1	no	3.758	3.817	EPSD	COSMIC	1.803	Up-regulation
AGC_RSK_RSKp90_RPS6KA3_ST	Q14934	NFATC4	P51812	RPS6KA3	S278	G275S	275	Missense	distal	-3	no	1.447	1.822	EPSD	COSMIC	1.803	Gain
AGC_RSK_RSKp90_RPS6KA3_ST	Q14934	NFATC4	P51812	RPS6KA3	S281	R286W	286	Missense	distal	5	no	1.930	2.021	EPSD;PhosphoSitePlus	COSMIC	1.803	Up-regulation
AGC_RSK_RSKp90_RPS6KA3_ST	Q14934	NFATC4	P51812	RPS6KA3	S281	P277Q	277	Missense	distal	-4	no	1.930	1.916	EPSD;PhosphoSitePlus	COSMIC	1.803	Down-regulation
AGC_RSK_RSKp90_RPS6KA3_ST	Q14934	NFATC4	P51812	RPS6KA3	S281	S285P	285	Missense	distal	4	no	1.930	1.969	EPSD;PhosphoSitePlus	COSMIC	1.803	Up-regulation
AGC_RSK_RSKp90_RPS6KA3_ST	Q14934	NFATC4	P51812	RPS6KA3	S281	G275S	275	Missense	distal	-6	no	1.930	1.963	EPSD;PhosphoSitePlus	COSMIC	1.803	Up-regulation
AGC_RSK_RSKp90_RPS6KA3_ST	Q14934	NFATC4	P51812	RPS6KA3	S281	G288W	288	Missense	distal	7	no	1.930	1.924	EPSD;PhosphoSitePlus	COSMIC	1.803	Down-regulation
AGC_RSK_RSKp90_RPS6KA3_ST	Q14934	NFATC4	P51812	RPS6KA3	S281	P282A	282	Missense	proximal	1	no	1.930	1.911	EPSD;PhosphoSitePlus	COSMIC	1.803	Down-regulation
AGC_RSK_RSKp90_RPS6KA3_ST	Q14934	NFATC4	P51812	RPS6KA3	S281	R286H	286	Missense	distal	5	no	1.930	2.022	EPSD;PhosphoSitePlus	COSMIC	1.803	Up-regulation
AGC_RSK_RSKp90_RPS6KA3_ST	Q14934	NFATC4	P51812	RPS6KA3	S281	R287H	287	Missense	distal	6	no	1.930	1.862	EPSD;PhosphoSitePlus	COSMIC	1.803	Down-regulation
AGC_RSK_RSKp90_RPS6KA3_ST	Q14934	NFATC4	P51812	RPS6KA3	S281	R287S	287	Missense	distal	6	no	1.930	1.911	EPSD;PhosphoSitePlus	COSMIC	1.803	Down-regulation
AGC_RSK_RSKp90_RPS6KA3_ST	Q14934	NFATC4	P51812	RPS6KA3	S281	S281F	281	Missense	central	0	yes	1.930	0.000	EPSD;PhosphoSitePlus	COSMIC	1.803	Loss
AGC_RSK_RSKp90_RPS6KA3_ST	Q14934	NFATC4	P51812	RPS6KA3	S281	S274L	274	Missense	distal	-7	no	1.930	1.949	EPSD;PhosphoSitePlus	COSMIC	1.803	Up-regulation
AGC_RSK_RSKp90_RPS6KA3_ST	Q14934	NFATC4	P51812	RPS6KA3	S285	R286W	286	Missense	proximal	1	no	1.826	1.916	PhosphoSitePlus;EPSD	COSMIC	1.803	Up-regulation
AGC_RSK_RSKp90_RPS6KA3_ST	Q14934	NFATC4	P51812	RPS6KA3	S285	S285P	285	Missense	central	0	yes	1.826	0.000	PhosphoSitePlus;EPSD	COSMIC	1.803	Loss
AGC_RSK_RSKp90_RPS6KA3_ST	Q14934	NFATC4	P51812	RPS6KA3	S285	P282A	282	Missense	distal	-3	no	1.826	1.830	PhosphoSitePlus;EPSD	COSMIC	1.803	Up-regulation
AGC_RSK_RSKp90_RPS6KA3_ST	Q14934	NFATC4	P51812	RPS6KA3	S285	R286H	286	Missense	proximal	1	no	1.826	1.918	PhosphoSitePlus;EPSD	COSMIC	1.803	Up-regulation
AGC_RSK_RSKp90_RPS6KA3_ST	Q14934	NFATC4	P51812	RPS6KA3	S285	R287H	287	Missense	proximal	2	no	1.826	1.725	PhosphoSitePlus;EPSD	COSMIC	1.803	Loss
AGC_RSK_RSKp90_RPS6KA3_ST	Q14934	NFATC4	P51812	RPS6KA3	S285	R287S	287	Missense	proximal	2	no	1.826	1.819	PhosphoSitePlus;EPSD	COSMIC	1.803	Down-regulation
AGC_RSK_RSKp90_RPS6KA3_ST	Q14934	NFATC4	P51812	RPS6KA3	S285	S281F	281	Missense	distal	-4	no	1.826	1.684	PhosphoSitePlus;EPSD	COSMIC	1.803	Loss
AGC_RSK_RSKp90_RPS6KA3_ST	Q14934	NFATC4	P51812	RPS6KA3	S285	G291R	291	Missense	distal	6	no	1.826	1.890	PhosphoSitePlus;EPSD	COSMIC	1.803	Up-regulation
AGC_RSK_RSKp90_RPS6KA3_ST	Q14934	NFATC4	P51812	RPS6KA3	S289	R286W	286	Missense	distal	-3	no	4.121	1.579	EPSD;PhosphoSitePlus	COSMIC	1.803	Loss
AGC_RSK_RSKp90_RPS6KA3_ST	Q14934	NFATC4	P51812	RPS6KA3	S289	S285P	285	Missense	distal	-4	no	4.121	4.065	EPSD;PhosphoSitePlus	COSMIC	1.803	Down-regulation
AGC_RSK_RSKp90_RPS6KA3_ST	Q14934	NFATC4	P51812	RPS6KA3	S289	G288W	288	Missense	proximal	-1	no	4.121	4.118	EPSD;PhosphoSitePlus	COSMIC	1.803	Down-regulation
AGC_RSK_RSKp90_RPS6KA3_ST	Q14934	NFATC4	P51812	RPS6KA3	S289	P282A	282	Missense	distal	-7	no	4.121	4.117	EPSD;PhosphoSitePlus	COSMIC	1.803	Down-regulation
AGC_RSK_RSKp90_RPS6KA3_ST	Q14934	NFATC4	P51812	RPS6KA3	S289	R286H	286	Missense	distal	-3	no	4.121	1.583	EPSD;PhosphoSitePlus	COSMIC	1.803	Loss
AGC_RSK_RSKp90_RPS6KA3_ST	Q14934	NFATC4	P51812	RPS6KA3	S289	R287H	287	Missense	proximal	-2	no	4.121	3.565	EPSD;PhosphoSitePlus	COSMIC	1.803	Down-regulation
AGC_RSK_RSKp90_RPS6KA3_ST	Q14934	NFATC4	P51812	RPS6KA3	S289	R287S	287	Missense	proximal	-2	no	4.121	3.706	EPSD;PhosphoSitePlus	COSMIC	1.803	Down-regulation
AGC_RSK_RSKp90_RPS6KA3_ST	Q14934	NFATC4	P51812	RPS6KA3	S289	G291R	291	Missense	proximal	2	no	4.121	4.214	EPSD;PhosphoSitePlus	COSMIC	1.803	Up-regulation
AGC_RSK_RSKp90_RPS6KA3_ST	Q14934	NFATC4	P51812	RPS6KA3	S289	G294E	294	Missense	distal	5	no	4.121	4.095	EPSD;PhosphoSitePlus	COSMIC	1.803	Down-regulation
AGC_RSK_RSKp90_RPS6KA3_ST	Q14934	NFATC4	P51812	RPS6KA3	S325	P327S	327	Missense	proximal	2	no	1.753	1.824	EPSD	COSMIC	1.803	Gain
AGC_RSK_RSKp90_RPS6KA3_ST	Q14934	NFATC4	P51812	RPS6KA3	S325	R332L	332	Missense	distal	7	no	1.753	1.809	EPSD	COSMIC	1.803	Gain
AGC_RSK_RSKp90_RPS6KA3_ST	Q14934	NFATC4	P51812	RPS6KA3	S334	R332W	332	Missense	proximal	-2	no	4.170	3.612	EPSD	COSMIC	1.803	Down-regulation
AGC_RSK_RSKp90_RPS6KA3_ST	Q14934	NFATC4	P51812	RPS6KA3	S334	S335P	335	Missense	proximal	1	no	4.170	4.209	EPSD	COSMIC	1.803	Up-regulation
AGC_RSK_RSKp90_RPS6KA3_ST	Q14934	NFATC4	P51812	RPS6KA3	S334	P327L	327	Missense	distal	-7	no	4.170	4.179	EPSD	COSMIC	1.803	Up-regulation
AGC_RSK_RSKp90_RPS6KA3_ST	Q14934	NFATC4	P51812	RPS6KA3	S334	R331Q	331	Missense	distal	-3	no	4.170	1.664	EPSD	COSMIC	1.803	Loss
AGC_RSK_RSKp90_RPS6KA3_ST	Q14934	NFATC4	P51812	RPS6KA3	S334	P327S	327	Missense	distal	-7	no	4.170	4.160	EPSD	COSMIC	1.803	Down-regulation
AGC_RSK_RSKp90_RPS6KA3_ST	Q14934	NFATC4	P51812	RPS6KA3	S334	R331W	331	Missense	distal	-3	no	4.170	1.628	EPSD	COSMIC	1.803	Loss
AGC_RSK_RSKp90_RPS6KA3_ST	Q14934	NFATC4	P51812	RPS6KA3	S334	K329R	329	Missense	distal	-5	no	4.170	4.458	EPSD	COSMIC	1.803	Up-regulation
AGC_RSK_RSKp90_RPS6KA3_ST	Q14934	NFATC4	P51812	RPS6KA3	S334	R332L	332	Missense	proximal	-2	no	4.170	3.664	EPSD	COSMIC	1.803	Down-regulation
AGC_RSK_RSKp90_RPS6KA3_ST	Q14934	NFATC4	P51812	RPS6KA3	S335	R332W	332	Missense	distal	-3	no	3.504	0.962	EPSD	COSMIC	1.803	Loss
AGC_RSK_RSKp90_RPS6KA3_ST	Q14934	NFATC4	P51812	RPS6KA3	S335	S335P	335	Missense	central	0	yes	3.504	0.000	EPSD	COSMIC	1.803	Loss
AGC_RSK_RSKp90_RPS6KA3_ST	Q14934	NFATC4	P51812	RPS6KA3	S335	R331Q	331	Missense	distal	-4	no	3.504	3.339	EPSD	COSMIC	1.803	Down-regulation
AGC_RSK_RSKp90_RPS6KA3_ST	Q14934	NFATC4	P51812	RPS6KA3	S335	P342A	342	Missense	distal	7	no	3.504	3.496	EPSD	COSMIC	1.803	Down-regulation
AGC_RSK_RSKp90_RPS6KA3_ST	Q14934	NFATC4	P51812	RPS6KA3	S335	R331W	331	Missense	distal	-4	no	3.504	3.314	EPSD	COSMIC	1.803	Down-regulation
AGC_RSK_RSKp90_RPS6KA3_ST	Q14934	NFATC4	P51812	RPS6KA3	S335	K329R	329	Missense	distal	-6	no	3.504	3.558	EPSD	COSMIC	1.803	Up-regulation
AGC_RSK_RSKp90_RPS6KA3_ST	Q14934	NFATC4	P51812	RPS6KA3	S335	R332L	332	Missense	distal	-3	no	3.504	1.274	EPSD	COSMIC	1.803	Loss
AGC_RSK_RSKp90_RPS6KA3_ST	Q14934	NFATC4	P51812	RPS6KA3	S349	P355S	355	Missense	distal	6	no	1.771	1.806	EPSD	COSMIC	1.803	Gain
AGC_RSK_RSKp90_RPS6KA3_ST	Q14934	NFATC4	P51812	RPS6KA3	S532	L527I	527	Missense	distal	-5	no	1.843	1.820	EPSD	COSMIC	1.803	Down-regulation
AGC_RSK_RSKp90_RPS6KA3_ST	Q14934	NFATC4	P51812	RPS6KA3	S532	R537M	537	Missense	distal	5	no	1.843	1.923	EPSD	COSMIC	1.803	Up-regulation
AGC_RSK_RSKp90_RPS6KA3_ST	Q14934	NFATC4	P51812	RPS6KA3	S532	R530Q	530	Missense	proximal	-2	no	1.843	1.318	EPSD	COSMIC	1.803	Loss
AGC_RSK_RSKp90_RPS6KA3_ST	Q14934	NFATC4	P51812	RPS6KA3	S532	G525R	525	Missense	distal	-7	no	1.843	1.817	EPSD	COSMIC	1.803	Down-regulation
AGC_RSK_RSKp90_RPS6KA3_ST	Q14934	NFATC4	P51812	RPS6KA3	S532	R530W	530	Missense	proximal	-2	no	1.843	1.285	EPSD	COSMIC	1.803	Loss
AGC_RSK_RSKp90_RPS6KA3_ST	Q14934	NFATC4	P51812	RPS6KA3	S532	E535K	535	Missense	distal	3	no	1.843	1.841	EPSD	COSMIC	1.803	Down-regulation
AGC_RSK_RSKp90_RPS6KA3_ST	Q14934	NFATC4	P51812	RPS6KA3	S532	R537Q	537	Missense	distal	5	no	1.843	1.910	EPSD	COSMIC	1.803	Up-regulation
AGC_RSK_RSKp90_RPS6KA3_ST	Q14934	NFATC4	P51812	RPS6KA3	S676	P677A	677	Missense	proximal	1	no	4.037	4.018	EPSD;PhosphoSitePlus	COSMIC	1.803	Down-regulation
AGC_RSK_RSKp90_RPS6KA3_ST	Q14934	NFATC4	P51812	RPS6KA3	S676	S676N	676	Missense	central	0	yes	4.037	0.000	EPSD;PhosphoSitePlus	COSMIC	1.803	Loss
AGC_RSK_RSKp90_RPS6KA3_ST	Q14934	NFATC4	P51812	RPS6KA3	S676	G671W	671	Missense	distal	-5	no	4.037	4.024	EPSD;PhosphoSitePlus	COSMIC	1.803	Down-regulation
AGC_RSK_RSKp90_RPS6KA3_ST	Q14934	NFATC4	P51812	RPS6KA3	S676	R675H	675	Missense	proximal	-1	no	4.037	3.969	EPSD;PhosphoSitePlus	COSMIC;CCLE	1.803	Down-regulation
AGC_RSK_RSKp90_RPS6KA3_ST	Q14934	NFATC4	P51812	RPS6KA3	S676	R672W	672	Missense	distal	-4	no	4.037	3.847	EPSD;PhosphoSitePlus	COSMIC	1.803	Down-regulation
AGC_RSK_RSKp90_RPS6KA3_ST	Q14934	NFATC4	P51812	RPS6KA3	S676	S669A	669	Missense	distal	-7	no	4.037	4.043	EPSD;PhosphoSitePlus	COSMIC	1.803	Up-regulation
AGC_RSK_RSKp90_RPS6KA3_ST	Q14934	NFATC4	P51812	RPS6KA3	S676	G671R	671	Missense	distal	-5	no	4.037	4.406	EPSD;PhosphoSitePlus	COSMIC	1.803	Up-regulation
AGC_RSK_RSKp90_RPS6KA3_ST	Q14934	NFATC4	P51812	RPS6KA3	S676	F683C	683	Missense	distal	7	no	4.037	4.024	EPSD;PhosphoSitePlus	COSMIC	1.803	Down-regulation
AGC_RSK_RSKp90_RPS6KA3_ST	Q14934	NFATC4	P51812	RPS6KA3	S676	R675C	675	Missense	proximal	-1	no	4.037	3.964	EPSD;PhosphoSitePlus	COSMIC	1.803	Down-regulation
AGC_RSK_RSKp90_RPS6KA3_ST	Q99683	MAP3K5	P51812	RPS6KA3	S82	G81S	81	Missense	proximal	-1	no	2.365	2.401	EPSD	COSMIC	1.803	Up-regulation
AGC_RSK_RSKp90_RPS6KA3_ST	Q99683	MAP3K5	P51812	RPS6KA3	S82	G87S	87	Missense	distal	5	no	2.365	2.294	EPSD	COSMIC	1.803	Down-regulation
AGC_RSK_RSKp90_RPS6KA3_ST	Q99683	MAP3K5	P51812	RPS6KA3	S83	G81S	81	Missense	proximal	-2	no	4.412	4.530	PhosphoSitePlus;EPSD	COSMIC	1.803	Up-regulation
AGC_RSK_RSKp90_RPS6KA3_ST	Q99683	MAP3K5	P51812	RPS6KA3	S83	G87S	87	Missense	distal	4	no	4.412	4.350	PhosphoSitePlus;EPSD	COSMIC	1.803	Down-regulation
AGC_RSK_RSKp90_RPS6KA3_ST	Q99683	MAP3K5	P51812	RPS6KA3	S719	Q720E	720	Missense	proximal	1	no	2.810	2.817	EPSD	COSMIC	1.803	Up-regulation
AGC_RSK_RSKp90_RPS6KA3_ST	Q99683	MAP3K5	P51812	RPS6KA3	S719	R714K	714	Missense	distal	-5	no	2.810	2.522	EPSD	COSMIC	1.803	Down-regulation
AGC_RSK_RSKp90_RPS6KA3_ST	Q99683	MAP3K5	P51812	RPS6KA3	S966	V969I	969	Missense	distal	3	no	4.046	4.045	EPSD	COSMIC	1.803	Down-regulation
AGC_RSK_RSKp90_RPS6KA3_ST	Q99683	MAP3K5	P51812	RPS6KA3	T1015	G1012R	1012	Missense	distal	-3	no	-0.561	1.821	EPSD	COSMIC	1.803	Gain
AGC_RSK_RSKp90_RPS6KA3_ST	Q99683	MAP3K5	P51812	RPS6KA3	T1059	A1052T	1052	Missense	distal	-7	no	2.286	2.301	EPSD	COSMIC	1.803	Up-regulation
AGC_RSK_RSKp90_RPS6KA3_ST	Q99683	MAP3K5	P51812	RPS6KA3	S1072	E1071K	1071	Missense	proximal	-1	no	2.149	2.167	EPSD	COSMIC	1.803	Up-regulation
AGC_RSK_RSKp90_RPS6KA3_ST	Q92934	BAD	P51812	RPS6KA3	S74	A78E	78	Missense	distal	4	no	1.804	1.821	EPSD	COSMIC	1.803	Up-regulation
AGC_RSK_RSKp90_RPS6KA3_ST	Q92934	BAD	P51812	RPS6KA3	S75	A78E	78	Missense	distal	3	no	4.372	4.374	PhosphoSitePlus;EPSD	COSMIC	1.803	Up-regulation
AGC_RSK_RSKp90_RPS6KA3_ST	Q92934	BAD	P51812	RPS6KA3	S97	P102L	102	Missense	distal	5	no	3.885	3.923	EPSD	COSMIC	1.803	Up-regulation
AGC_RSK_RSKp90_RPS6KA3_ST	Q92934	BAD	P51812	RPS6KA3	S97	S97P	97	Missense	central	0	yes	3.885	0.000	EPSD	COSMIC	1.803	Loss
AGC_RSK_RSKp90_RPS6KA3_ST	Q92934	BAD	P51812	RPS6KA3	S97	R98H	98	Missense	proximal	1	no	3.885	3.977	EPSD	COSMIC	1.803	Up-regulation
AGC_RSK_RSKp90_RPS6KA3_ST	Q92934	BAD	P51812	RPS6KA3	S97	P101S	101	Missense	distal	4	no	3.885	3.845	EPSD	COSMIC	1.803	Down-regulation
AGC_RSK_RSKp90_RPS6KA3_ST	Q92934	BAD	P51812	RPS6KA3	S99	P102L	102	Missense	distal	3	no	4.010	4.014	EPSD;PhosphoSitePlus	COSMIC	1.803	Up-regulation
AGC_RSK_RSKp90_RPS6KA3_ST	Q92934	BAD	P51812	RPS6KA3	S99	S97P	97	Missense	proximal	-2	no	4.010	3.956	EPSD;PhosphoSitePlus	COSMIC	1.803	Down-regulation
AGC_RSK_RSKp90_RPS6KA3_ST	Q92934	BAD	P51812	RPS6KA3	S99	R98H	98	Missense	proximal	-1	no	4.010	3.941	EPSD;PhosphoSitePlus	COSMIC	1.803	Down-regulation
AGC_RSK_RSKp90_RPS6KA3_ST	Q92934	BAD	P51812	RPS6KA3	S99	P101S	101	Missense	proximal	2	no	4.010	4.081	EPSD;PhosphoSitePlus	COSMIC	1.803	Up-regulation
AGC_RSK_RSKp90_RPS6KA3_ST	Q92934	BAD	P51812	RPS6KA3	S118	S124F	124	Missense	distal	6	no	4.319	4.251	EPSD	COSMIC	1.803	Down-regulation
AGC_RSK_RSKp90_RPS6KA3_ST	Q92934	BAD	P51812	RPS6KA3	S134	K127N	127	Missense	distal	-7	no	3.650	3.658	EPSD	COSMIC	1.803	Up-regulation
AGC_RSK_RSKp90_RPS6KA3_ST	Q92934	BAD	P51812	RPS6KA3	S134	K133N	133	Missense	proximal	-1	no	3.650	3.636	EPSD	COSMIC	1.803	Down-regulation
AGC_RSK_RSKp90_RPS6KA3_ST	Q92934	BAD	P51812	RPS6KA3	S144	W147R	147	Missense	distal	3	no	1.897	1.889	EPSD	COSMIC	1.803	Down-regulation
AGC_RSK_RSKp90_RPS6KA3_ST	Q92934	BAD	P51812	RPS6KA3	S145	W147R	147	Missense	proximal	2	no	3.509	3.612	EPSD	COSMIC	1.803	Up-regulation
AGC_RSK_RSKp90_RPS6KA3_ST	Q92934	BAD	P51812	RPS6KA3	S164	R161S	161	Missense	distal	-3	no	3.626	1.619	EPSD	COSMIC;GDSC	1.803	Loss
AGC_RSK_RSKp90_RPS6KA3_ST	Q92934	BAD	P51812	RPS6KA3	S164	P166S	166	Missense	proximal	2	no	3.626	3.697	EPSD	COSMIC	1.803	Up-regulation
AGC_RSK_RSKp90_RPS6KA3_ST	Q92934	BAD	P51812	RPS6KA3	S164	R161G	161	Missense	distal	-3	no	3.626	1.244	EPSD	COSMIC	1.803	Loss
AGC_RSK_RSKp90_RPS6KA3_ST	Q8IX03	WWC1	P51812	RPS6KA3	S33	R40S	40	Missense	distal	7	no	3.708	3.719	EPSD	COSMIC	1.803	Up-regulation
AGC_RSK_RSKp90_RPS6KA3_ST	Q8IX03	WWC1	P51812	RPS6KA3	S141	V134I	134	Missense	distal	-7	no	1.934	1.930	EPSD	COSMIC;CCLE	1.803	Down-regulation
AGC_RSK_RSKp90_RPS6KA3_ST	Q8IX03	WWC1	P51812	RPS6KA3	S141	K138T	138	Missense	distal	-3	no	1.934	1.462	EPSD	COSMIC	1.803	Loss
AGC_RSK_RSKp90_RPS6KA3_ST	Q8IX03	WWC1	P51812	RPS6KA3	S141	S141F	141	Missense	central	0	yes	1.934	0.000	EPSD	COSMIC	1.803	Loss
AGC_RSK_RSKp90_RPS6KA3_ST	Q8IX03	WWC1	P51812	RPS6KA3	S208	S208R	208	Missense	central	0	yes	1.900	0.000	EPSD	COSMIC	1.803	Loss
AGC_RSK_RSKp90_RPS6KA3_ST	Q8IX03	WWC1	P51812	RPS6KA3	S208	D204Y	204	Missense	distal	-4	no	1.900	1.898	EPSD	COSMIC	1.803	Down-regulation
AGC_RSK_RSKp90_RPS6KA3_ST	Q8IX03	WWC1	P51812	RPS6KA3	S268	P272R	272	Missense	distal	4	no	1.826	1.790	EPSD	COSMIC	1.803	Loss
AGC_RSK_RSKp90_RPS6KA3_ST	Q8IX03	WWC1	P51812	RPS6KA3	S270	Q276R	276	Missense	distal	6	no	1.810	1.866	EPSD	COSMIC	1.803	Up-regulation
AGC_RSK_RSKp90_RPS6KA3_ST	Q8IX03	WWC1	P51812	RPS6KA3	S270	P272R	272	Missense	proximal	2	no	1.810	1.888	EPSD	COSMIC	1.803	Up-regulation
AGC_RSK_RSKp90_RPS6KA3_ST	Q8IX03	WWC1	P51812	RPS6KA3	S358	G365W	365	Missense	distal	7	no	3.731	3.725	EPSD	COSMIC	1.803	Down-regulation
AGC_RSK_RSKp90_RPS6KA3_ST	Q8IX03	WWC1	P51812	RPS6KA3	S358	R360H	360	Missense	proximal	2	no	3.731	3.630	EPSD	COSMIC	1.803	Down-regulation
AGC_RSK_RSKp90_RPS6KA3_ST	Q8IX03	WWC1	P51812	RPS6KA3	S437	S434F	434	Missense	distal	-3	no	1.936	1.083	EPSD	COSMIC	1.803	Loss
AGC_RSK_RSKp90_RPS6KA3_ST	Q8IX03	WWC1	P51812	RPS6KA3	S438	S434F	434	Missense	distal	-4	no	2.135	1.992	EPSD	COSMIC	1.803	Down-regulation
AGC_RSK_RSKp90_RPS6KA3_ST	Q8IX03	WWC1	P51812	RPS6KA3	S441	S434F	434	Missense	distal	-7	no	1.947	1.972	EPSD	COSMIC	1.803	Up-regulation
AGC_RSK_RSKp90_RPS6KA3_ST	Q8IX03	WWC1	P51812	RPS6KA3	S441	S448Y	448	Missense	distal	7	no	1.947	1.993	EPSD	COSMIC	1.803	Up-regulation
AGC_RSK_RSKp90_RPS6KA3_ST	Q8IX03	WWC1	P51812	RPS6KA3	S525	L521V	521	Missense	distal	-4	no	4.098	4.068	EPSD	COSMIC	1.803	Down-regulation
AGC_RSK_RSKp90_RPS6KA3_ST	Q8IX03	WWC1	P51812	RPS6KA3	T912	P913S	913	Missense	proximal	1	no	1.905	1.865	EPSD	COSMIC	1.803	Down-regulation
AGC_RSK_RSKp90_RPS6KA3_ST	Q8IX03	WWC1	P51812	RPS6KA3	S922	K928Q	928	Missense	distal	6	no	1.866	1.853	EPSD	COSMIC	1.803	Down-regulation
AGC_RSK_RSKp90_RPS6KA3_ST	Q8IX03	WWC1	P51812	RPS6KA3	T923	K928Q	928	Missense	distal	5	no	1.879	1.894	EPSD	COSMIC	1.803	Up-regulation
AGC_RSK_RSKp90_RPS6KA3_ST	Q8IX03	WWC1	P51812	RPS6KA3	T929	K928Q	928	Missense	proximal	-1	no	2.595	2.582	EPSD;PhosphoSitePlus	COSMIC	1.803	Down-regulation
AGC_RSK_RSKp90_RPS6KA3_ST	Q8IX03	WWC1	P51812	RPS6KA3	S931	K928Q	928	Missense	distal	-3	no	1.905	1.365	EPSD	COSMIC	1.803	Loss
AGC_RSK_RSKp90_RPS6KA3_ST	Q8IX03	WWC1	P51812	RPS6KA3	S947	T951I	951	Missense	distal	4	no	3.802	3.784	PhosphoSitePlus;EPSD	COSMIC	1.803	Down-regulation
AGC_RSK_RSKp90_RPS6KA3_ST	Q8IX03	WWC1	P51812	RPS6KA3	S953	T951I	951	Missense	proximal	-2	no	1.896	1.903	EPSD	COSMIC	1.803	Up-regulation
AGC_RSK_RSKp90_RPS6KA3_ST	Q8IX03	WWC1	P51812	RPS6KA3	S974	S981F	981	Missense	distal	7	no	2.314	2.372	EPSD	COSMIC	1.803	Up-regulation
AGC_RSK_RSKp90_RPS6KA3_ST	Q8IX03	WWC1	P51812	RPS6KA3	S974	M970I	970	Missense	distal	-4	no	2.314	2.296	EPSD	COSMIC	1.803	Down-regulation
AGC_RSK_RSKp90_RPS6KA3_ST	Q8IX03	WWC1	P51812	RPS6KA3	S974	S981L	981	Missense	distal	7	no	2.314	2.360	EPSD	COSMIC	1.803	Up-regulation
AGC_RSK_RSKp90_RPS6KA3_ST	Q8IX03	WWC1	P51812	RPS6KA3	S975	S981F	981	Missense	distal	6	no	3.999	3.931	EPSD	COSMIC	1.803	Down-regulation
AGC_RSK_RSKp90_RPS6KA3_ST	Q8IX03	WWC1	P51812	RPS6KA3	S975	M970I	970	Missense	distal	-5	no	3.999	3.976	EPSD	COSMIC	1.803	Down-regulation
AGC_RSK_RSKp90_RPS6KA3_ST	Q8IX03	WWC1	P51812	RPS6KA3	S975	S981L	981	Missense	distal	6	no	3.999	3.946	EPSD	COSMIC	1.803	Down-regulation
AGC_RSK_RSKp90_RPS6KA3_ST	Q8IX03	WWC1	P51812	RPS6KA3	S978	S981F	981	Missense	distal	3	no	1.965	1.975	EPSD	COSMIC	1.803	Up-regulation
AGC_RSK_RSKp90_RPS6KA3_ST	Q8IX03	WWC1	P51812	RPS6KA3	S978	S981L	981	Missense	distal	3	no	1.965	1.973	EPSD	COSMIC	1.803	Up-regulation
AGC_RSK_RSKp90_RPS6KA3_ST	Q14790	CASP8	P51812	RPS6KA3	S170	I167N	167	Missense	distal	-3	no	1.552	1.894	EPSD	COSMIC	1.803	Gain
AGC_RSK_RSKp90_RPS6KA3_ST	Q14790	CASP8	P51812	RPS6KA3	S186	E184Q	184	Missense	proximal	-2	no	1.810	1.815	EPSD	COSMIC	1.803	Up-regulation
AGC_RSK_RSKp90_RPS6KA3_ST	Q14790	CASP8	P51812	RPS6KA3	S186	S186N	186	Missense	central	0	yes	1.810	0.000	EPSD	COSMIC	1.803	Loss
AGC_RSK_RSKp90_RPS6KA3_ST	Q14790	CASP8	P51812	RPS6KA3	S186	E179D	179	Missense	distal	-7	no	1.810	1.816	EPSD	COSMIC	1.803	Up-regulation
AGC_RSK_RSKp90_RPS6KA3_ST	Q14790	CASP8	P51812	RPS6KA3	S186	S188A	188	Missense	proximal	2	no	1.810	1.750	EPSD	COSMIC	1.803	Loss
AGC_RSK_RSKp90_RPS6KA3_ST	Q14790	CASP8	P51812	RPS6KA3	S186	E179Q	179	Missense	distal	-7	no	1.810	1.809	EPSD	COSMIC	1.803	Down-regulation
AGC_RSK_RSKp90_RPS6KA3_ST	Q14790	CASP8	P51812	RPS6KA3	S188	E184Q	184	Missense	distal	-4	no	3.586	3.590	EPSD	COSMIC	1.803	Up-regulation
AGC_RSK_RSKp90_RPS6KA3_ST	Q14790	CASP8	P51812	RPS6KA3	S188	S186N	186	Missense	proximal	-2	no	3.586	3.536	EPSD	COSMIC	1.803	Down-regulation
AGC_RSK_RSKp90_RPS6KA3_ST	Q14790	CASP8	P51812	RPS6KA3	S188	S188A	188	Missense	central	0	yes	3.586	0.000	EPSD	COSMIC	1.803	Loss
AGC_RSK_RSKp90_RPS6KA3_ST	Q14790	CASP8	P51812	RPS6KA3	T263	H264N	264	Missense	proximal	1	no	2.347	2.331	PhosphoSitePlus	COSMIC	1.803	Down-regulation
AGC_RSK_RSKp90_RPS6KA3_ST	Q14790	CASP8	P51812	RPS6KA3	T263	D266N	266	Missense	distal	3	no	2.347	2.345	PhosphoSitePlus	COSMIC	1.803	Down-regulation
AGC_RSK_RSKp90_RPS6KA3_ST	Q14790	CASP8	P51812	RPS6KA3	T263	H264Y	264	Missense	proximal	1	no	2.347	2.358	PhosphoSitePlus	COSMIC	1.803	Up-regulation
AGC_RSK_RSKp90_RPS6KA3_ST	Q14790	CASP8	P51812	RPS6KA3	T263	A267T	267	Missense	distal	4	no	2.347	2.397	PhosphoSitePlus	COSMIC	1.803	Up-regulation
AGC_RSK_RSKp90_RPS6KA3_ST	Q14790	CASP8	P51812	RPS6KA3	T263	G268V	268	Missense	distal	5	no	2.347	2.355	PhosphoSitePlus	COSMIC	1.803	Up-regulation
AGC_RSK_RSKp90_RPS6KA3_ST	Q14790	CASP8	P51812	RPS6KA3	T263	G268R	268	Missense	distal	5	no	2.347	2.245	PhosphoSitePlus	COSMIC	1.803	Down-regulation
AGC_RSK_RSKp90_RPS6KA3_ST	Q14790	CASP8	P51812	RPS6KA3	T263	D259Y	259	Missense	distal	-4	no	2.347	2.345	PhosphoSitePlus	COSMIC	1.803	Down-regulation
AGC_RSK_RSKp90_RPS6KA3_ST	Q14790	CASP8	P51812	RPS6KA3	T263	R258S	258	Missense	distal	-5	no	2.347	2.030	PhosphoSitePlus	COSMIC	1.803	Down-regulation
AGC_RSK_RSKp90_RPS6KA3_ST	Q14790	CASP8	P51812	RPS6KA3	T263	S256N	256	Missense	distal	-7	no	2.347	2.359	PhosphoSitePlus	COSMIC	1.803	Up-regulation
AGC_RSK_RSKp90_RPS6KA3_ST	Q14790	CASP8	P51812	RPS6KA3	T263	R260S	260	Missense	distal	-3	no	2.347	0.339	PhosphoSitePlus	COSMIC	1.803	Loss
AGC_RSK_RSKp90_RPS6KA3_ST	Q14790	CASP8	P51812	RPS6KA3	T263	G262V	262	Missense	proximal	-1	no	2.347	2.332	PhosphoSitePlus	COSMIC	1.803	Down-regulation
AGC_RSK_RSKp90_RPS6KA3_ST	Q14790	CASP8	P51812	RPS6KA3	S347	C345R	345	Missense	proximal	-2	no	1.598	2.179	EPSD	COSMIC	1.803	Gain
AGC_RSK_RSKp90_RPS6KA3_ST	P16220	CREB1	P51812	RPS6KA3	S98	S103N	103	Missense	distal	5	no	3.726	3.772	EPSD	COSMIC	1.803	Up-regulation
AGC_RSK_RSKp90_RPS6KA3_ST	P16220	CREB1	P51812	RPS6KA3	S98	R95I	95	Missense	distal	-3	no	3.726	1.259	EPSD	COSMIC	1.803	Loss
AGC_RSK_RSKp90_RPS6KA3_ST	P16220	CREB1	P51812	RPS6KA3	S98	I102M	102	Missense	distal	4	no	3.726	3.716	EPSD	COSMIC	1.803	Down-regulation
AGC_RSK_RSKp90_RPS6KA3_ST	P16220	CREB1	P51812	RPS6KA3	S111	S117N	117	Missense	distal	6	no	1.833	1.794	EPSD	COSMIC	1.803	Loss
AGC_RSK_RSKp90_RPS6KA3_ST	P16220	CREB1	P51812	RPS6KA3	S111	V118L	118	Missense	distal	7	no	1.833	1.829	EPSD	COSMIC	1.803	Down-regulation
AGC_RSK_RSKp90_RPS6KA3_ST	P16220	CREB1	P51812	RPS6KA3	S111	E109K	109	Missense	proximal	-2	no	1.833	1.944	EPSD	COSMIC	1.803	Up-regulation
AGC_RSK_RSKp90_RPS6KA3_ST	P16220	CREB1	P51812	RPS6KA3	S111	V118I	118	Missense	distal	7	no	1.833	1.823	EPSD	COSMIC	1.803	Down-regulation
AGC_RSK_RSKp90_RPS6KA3_ST	P16220	CREB1	P51812	RPS6KA3	S129	L128R	128	Missense	proximal	-1	no	1.762	1.833	EPSD	COSMIC	1.803	Gain
AGC_RSK_RSKp90_RPS6KA3_ST	P16220	CREB1	P51812	RPS6KA3	S133	L128R	128	Missense	distal	-5	no	4.306	4.652	PhosphoSitePlus	COSMIC	1.803	Up-regulation
AGC_RSK_RSKp90_RPS6KA3_ST	P49841	GSK3B	P51812	RPS6KA3	T7	S9F	9	Missense	proximal	2	no	2.033	1.902	EPSD	COSMIC	1.803	Down-regulation
AGC_RSK_RSKp90_RPS6KA3_ST	P49841	GSK3B	P51812	RPS6KA3	T7	S2P	2	Missense	distal	-5	no	2.033	2.026	EPSD	COSMIC	1.803	Down-regulation
AGC_RSK_RSKp90_RPS6KA3_ST	P49841	GSK3B	P51812	RPS6KA3	S9	S9F	9	Missense	central	0	yes	4.283	0.000	PhosphoSitePlus	COSMIC	1.803	Loss
AGC_RSK_RSKp90_RPS6KA3_ST	P49841	GSK3B	P51812	RPS6KA3	S9	P16A	16	Missense	distal	7	no	4.283	4.274	PhosphoSitePlus	COSMIC	1.803	Down-regulation
AGC_RSK_RSKp90_RPS6KA3_ST	P49841	GSK3B	P51812	RPS6KA3	S9	S2P	2	Missense	distal	-7	no	4.283	4.293	PhosphoSitePlus	COSMIC	1.803	Up-regulation
AGC_RSK_RSKp90_RPS6KA3_ST	P49841	GSK3B	P51812	RPS6KA3	S35	D31Y	31	Missense	distal	-4	no	1.823	1.821	EPSD	COSMIC	1.803	Down-regulation
AGC_RSK_RSKp90_RPS6KA3_ST	P49841	GSK3B	P51812	RPS6KA3	S35	D33N	33	Missense	proximal	-2	no	1.823	1.931	EPSD	COSMIC	1.803	Up-regulation
AGC_RSK_RSKp90_RPS6KA3_ST	P49841	GSK3B	P51812	RPS6KA3	S35	S35R	35	Missense	central	0	yes	1.823	0.000	EPSD	COSMIC	1.803	Loss
AGC_RSK_RSKp90_RPS6KA3_ST	P49841	GSK3B	P51812	RPS6KA3	S35	V41G	41	Missense	distal	6	no	1.823	1.839	EPSD	COSMIC	1.803	Up-regulation
AGC_RSK_RSKp90_RPS6KA3_ST	P49841	GSK3B	P51812	RPS6KA3	S35	V37G	37	Missense	proximal	2	no	1.823	1.854	EPSD	COSMIC	1.803	Up-regulation
AGC_RSK_RSKp90_RPS6KA3_ST	P49841	GSK3B	P51812	RPS6KA3	S35	D33G	33	Missense	proximal	-2	no	1.823	1.864	EPSD	COSMIC;GDSC;CCLE	1.803	Up-regulation
AGC_RSK_RSKp90_RPS6KA3_ST	P49841	GSK3B	P51812	RPS6KA3	S35	D33H	33	Missense	proximal	-2	no	1.823	1.841	EPSD	COSMIC	1.803	Up-regulation
AGC_RSK_RSKp90_RPS6KA3_ST	P49841	GSK3B	P51812	RPS6KA3	S147	P154S	154	Missense	distal	7	no	3.392	3.365	EPSD	COSMIC	1.803	Down-regulation
AGC_RSK_RSKp90_RPS6KA3_ST	P49841	GSK3B	P51812	RPS6KA3	S147	Y146C	146	Missense	proximal	-1	no	3.392	3.393	EPSD	COSMIC	1.803	Up-regulation
AGC_RSK_RSKp90_RPS6KA3_ST	P49841	GSK3B	P51812	RPS6KA3	S147	R148Q	148	Missense	proximal	1	no	3.392	3.464	EPSD	COSMIC	1.803	Up-regulation
AGC_RSK_RSKp90_RPS6KA3_ST	P49841	GSK3B	P51812	RPS6KA3	S147	S147N	147	Missense	central	0	yes	3.392	0.000	EPSD	COSMIC	1.803	Loss
AGC_RSK_RSKp90_RPS6KA3_ST	P49841	GSK3B	P51812	RPS6KA3	S147	Y140C	140	Missense	distal	-7	no	3.392	3.391	EPSD	COSMIC	1.803	Down-regulation
AGC_RSK_RSKp90_RPS6KA3_ST	P49841	GSK3B	P51812	RPS6KA3	S147	A143G	143	Missense	distal	-4	no	3.392	3.353	EPSD	COSMIC	1.803	Down-regulation
AGC_RSK_RSKp90_RPS6KA3_ST	P49841	GSK3B	P51812	RPS6KA3	S147	R141S	141	Missense	distal	-6	no	3.392	3.344	EPSD	COSMIC	1.803	Down-regulation
AGC_RSK_RSKp90_RPS6KA3_ST	Q9H6Z4	RANBP3	P51812	RPS6KA3	S35	E39V	39	Missense	distal	4	no	1.785	1.810	EPSD	COSMIC;GDSC;CCLE	1.803	Gain
AGC_RSK_RSKp90_RPS6KA3_ST	Q9H6Z4	RANBP3	P51812	RPS6KA3	S74	P79S	79	Missense	distal	5	no	1.889	1.849	EPSD	COSMIC	1.803	Down-regulation
AGC_RSK_RSKp90_RPS6KA3_ST	Q9H6Z4	RANBP3	P51812	RPS6KA3	S74	S72R	72	Missense	proximal	-2	no	1.889	2.304	EPSD	COSMIC	1.803	Up-regulation
AGC_RSK_RSKp90_RPS6KA3_ST	Q9H6Z4	RANBP3	P51812	RPS6KA3	S74	S72G	72	Missense	proximal	-2	no	1.889	1.771	EPSD	COSMIC	1.803	Loss
AGC_RSK_RSKp90_RPS6KA3_ST	Q9H6Z4	RANBP3	P51812	RPS6KA3	T75	S72R	72	Missense	distal	-3	no	-0.094	1.913	EPSD	COSMIC	1.803	Gain
AGC_RSK_RSKp90_RPS6KA3_ST	Q9H6Z4	RANBP3	P51812	RPS6KA3	T124	K120R	120	Missense	distal	-4	no	1.813	1.940	EPSD	COSMIC	1.803	Up-regulation
AGC_RSK_RSKp90_RPS6KA3_ST	Q9H6Z4	RANBP3	P51812	RPS6KA3	S125	K120R	120	Missense	distal	-5	no	1.609	1.897	EPSD	COSMIC	1.803	Gain
AGC_RSK_RSKp90_RPS6KA3_ST	Q9H6Z4	RANBP3	P51812	RPS6KA3	S126	K120R	120	Missense	distal	-6	no	3.977	4.030	PhosphoSitePlus	COSMIC	1.803	Up-regulation
AGC_RSK_RSKp90_RPS6KA3_ST	Q9H6Z4	RANBP3	P51812	RPS6KA3	S221	D225N	225	Missense	distal	4	no	3.790	3.776	EPSD	COSMIC	1.803	Down-regulation
AGC_RSK_RSKp90_RPS6KA3_ST	Q9H6Z4	RANBP3	P51812	RPS6KA3	S240	E234Q	234	Missense	distal	-6	no	2.005	2.011	EPSD	COSMIC;GDSC;CCLE	1.803	Up-regulation
AGC_RSK_RSKp90_RPS6KA3_ST	Q9H6Z4	RANBP3	P51812	RPS6KA3	S333	M327I	327	Missense	distal	-6	no	3.229	3.222	EPSD	COSMIC	1.803	Down-regulation
AGC_RSK_RSKp90_RPS6KA3_ST	Q9H6Z4	RANBP3	P51812	RPS6KA3	S333	L332W	332	Missense	proximal	-1	no	3.229	3.231	EPSD	COSMIC	1.803	Up-regulation
AGC_RSK_RSKp90_RPS6KA3_ST	Q9H6Z4	RANBP3	P51812	RPS6KA3	S333	P334T	334	Missense	proximal	1	no	3.229	3.261	EPSD	COSMIC	1.803	Up-regulation
AGC_RSK_RSKp90_RPS6KA3_ST	P07101	TH	P51812	RPS6KA3	S19	R15S	15	Missense	distal	-4	no	3.611	3.515	EPSD	COSMIC	1.803	Down-regulation
AGC_RSK_RSKp90_RPS6KA3_ST	P07101	TH	P51812	RPS6KA3	S19	A17V	17	Missense	proximal	-2	no	3.611	3.440	EPSD	COSMIC;CCLE	1.803	Down-regulation
AGC_RSK_RSKp90_RPS6KA3_ST	P07101	TH	P51812	RPS6KA3	S19	S19C	19	Missense	central	0	yes	3.611	0.000	EPSD	COSMIC;GDSC;CCLE	1.803	Loss
AGC_RSK_RSKp90_RPS6KA3_ST	P07101	TH	P51812	RPS6KA3	S19	V18M	18	Missense	proximal	-1	no	3.611	3.630	EPSD	COSMIC	1.803	Up-regulation
AGC_RSK_RSKp90_RPS6KA3_ST	P07101	TH	P51812	RPS6KA3	S71	R64Q	64	Missense	distal	-7	no	4.398	4.417	EPSD;PhosphoSitePlus	COSMIC;CCLE	1.803	Up-regulation
AGC_RSK_RSKp90_RPS6KA3_ST	P07101	TH	P51812	RPS6KA3	S509	V506M	506	Missense	distal	-3	no	1.321	1.829	EPSD	COSMIC	1.803	Gain
AGC_RSK_RSKp90_RPS6KA3_ST	P19525	EIF2AK2	P51812	RPS6KA3	S181	S178F	178	Missense	distal	-3	no	1.851	0.997	EPSD	COSMIC;CCLE	1.803	Loss
AGC_RSK_RSKp90_RPS6KA3_ST	P19525	EIF2AK2	P51812	RPS6KA3	S181	D175Y	175	Missense	distal	-6	no	1.851	1.846	EPSD	COSMIC	1.803	Down-regulation
AGC_RSK_RSKp90_RPS6KA3_ST	P19525	EIF2AK2	P51812	RPS6KA3	S181	S179F	179	Missense	proximal	-2	no	1.851	1.613	EPSD	COSMIC	1.803	Loss
AGC_RSK_RSKp90_RPS6KA3_ST	P19525	EIF2AK2	P51812	RPS6KA3	S181	T185M	185	Missense	distal	4	no	1.851	1.823	EPSD	COSMIC	1.803	Down-regulation
AGC_RSK_RSKp90_RPS6KA3_ST	P19525	EIF2AK2	P51812	RPS6KA3	S242	S242F	242	Missense	central	0	yes	2.402	0.000	EPSD	COSMIC	1.803	Loss
AGC_RSK_RSKp90_RPS6KA3_ST	P19525	EIF2AK2	P51812	RPS6KA3	S242	P245S	245	Missense	distal	3	no	2.402	2.397	EPSD	COSMIC	1.803	Down-regulation
AGC_RSK_RSKp90_RPS6KA3_ST	P19525	EIF2AK2	P51812	RPS6KA3	T529	S530Y	530	Missense	proximal	1	no	2.234	2.296	EPSD	COSMIC	1.803	Up-regulation
AGC_RSK_RSKp90_RPS6KA3_ST	P19525	EIF2AK2	P51812	RPS6KA3	S530	S530Y	530	Missense	central	0	yes	1.974	0.000	EPSD	COSMIC	1.803	Loss
AGC_RSK_RSKp90_RPS6KA3_ST	P19525	EIF2AK2	P51812	RPS6KA3	T537	S530Y	530	Missense	distal	-7	no	1.788	1.807	EPSD	COSMIC	1.803	Gain
AGC_RSK_RSKp90_RPS6KA3_ST	P03372	ESR1	P51812	RPS6KA3	S154	A148E	148	Missense	distal	-6	no	3.503	3.488	EPSD	COSMIC	1.803	Down-regulation
AGC_RSK_RSKp90_RPS6KA3_ST	P03372	ESR1	P51812	RPS6KA3	S154	R151K	151	Missense	distal	-3	no	3.503	1.536	EPSD	COSMIC	1.803	Loss
AGC_RSK_RSKp90_RPS6KA3_ST	P03372	ESR1	P51812	RPS6KA3	S154	R158C	158	Missense	distal	4	no	3.503	3.562	EPSD	COSMIC	1.803	Up-regulation
AGC_RSK_RSKp90_RPS6KA3_ST	P03372	ESR1	P51812	RPS6KA3	S154	Q159L	159	Missense	distal	5	no	3.503	3.546	EPSD	COSMIC	1.803	Up-regulation
AGC_RSK_RSKp90_RPS6KA3_ST	P03372	ESR1	P51812	RPS6KA3	S154	R157Q	157	Missense	distal	3	no	3.503	3.508	EPSD	COSMIC	1.803	Up-regulation
AGC_RSK_RSKp90_RPS6KA3_ST	P03372	ESR1	P51812	RPS6KA3	S154	N156T	156	Missense	proximal	2	no	3.503	3.452	EPSD	COSMIC	1.803	Down-regulation
AGC_RSK_RSKp90_RPS6KA3_ST	P03372	ESR1	P51812	RPS6KA3	S154	G160D	160	Missense	distal	6	no	3.503	3.496	EPSD	COSMIC	1.803	Down-regulation
AGC_RSK_RSKp90_RPS6KA3_ST	P03372	ESR1	P51812	RPS6KA3	S154	P152S	152	Missense	proximal	-2	no	3.503	3.557	EPSD	COSMIC	1.803	Up-regulation
AGC_RSK_RSKp90_RPS6KA3_ST	P03372	ESR1	P51812	RPS6KA3	S154	P152L	152	Missense	proximal	-2	no	3.503	3.466	EPSD	COSMIC	1.803	Down-regulation
AGC_RSK_RSKp90_RPS6KA3_ST	P03372	ESR1	P51812	RPS6KA3	S167	G172R	172	Missense	distal	5	no	4.193	4.091	PhosphoSitePlus	COSMIC	1.803	Down-regulation
AGC_RSK_RSKp90_RPS6KA3_ST	P03372	ESR1	P51812	RPS6KA3	S167	M174I	174	Missense	distal	7	no	4.193	4.200	PhosphoSitePlus	COSMIC	1.803	Up-regulation
AGC_RSK_RSKp90_RPS6KA3_ST	P03372	ESR1	P51812	RPS6KA3	S167	D170Y	170	Missense	distal	3	no	4.193	4.194	PhosphoSitePlus	COSMIC	1.803	Up-regulation
AGC_RSK_RSKp90_RPS6KA3_ST	P03372	ESR1	P51812	RPS6KA3	S167	G160D	160	Missense	distal	-7	no	4.193	4.194	PhosphoSitePlus	COSMIC	1.803	Up-regulation
AGC_RSK_RSKp90_RPS6KA3_ST	P03372	ESR1	P51812	RPS6KA3	S236	R241G	241	Missense	distal	5	no	4.297	4.399	EPSD	COSMIC	1.803	Up-regulation
AGC_RSK_RSKp90_RPS6KA3_ST	P03372	ESR1	P51812	RPS6KA3	S236	R241W	241	Missense	distal	5	no	4.297	4.388	EPSD	COSMIC	1.803	Up-regulation
AGC_RSK_RSKp90_RPS6KA3_ST	P03372	ESR1	P51812	RPS6KA3	S236	R233G	233	Missense	distal	-3	no	4.297	1.915	EPSD	COSMIC	1.803	Down-regulation
AGC_RSK_RSKp90_RPS6KA3_ST	P03372	ESR1	P51812	RPS6KA3	S236	C237Y	237	Missense	proximal	1	no	4.297	4.300	EPSD	COSMIC	1.803	Up-regulation
AGC_RSK_RSKp90_RPS6KA3_ST	P03372	ESR1	P51812	RPS6KA3	S236	Q238H	238	Missense	proximal	2	no	4.297	4.278	EPSD	COSMIC;CCLE	1.803	Down-regulation
AGC_RSK_RSKp90_RPS6KA3_ST	P03372	ESR1	P51812	RPS6KA3	S236	R243L	243	Missense	distal	7	no	4.297	4.353	EPSD	COSMIC	1.803	Up-regulation
AGC_RSK_RSKp90_RPS6KA3_ST	P03372	ESR1	P51812	RPS6KA3	S305	K303R	303	Missense	proximal	-2	no	1.964	2.383	EPSD	COSMIC	1.803	Up-regulation
AGC_RSK_RSKp90_RPS6KA3_ST	P03372	ESR1	P51812	RPS6KA3	S305	K299R	299	Missense	distal	-6	no	1.964	2.017	EPSD	COSMIC	1.803	Up-regulation
AGC_RSK_RSKp90_RPS6KA3_ST	P03372	ESR1	P51812	RPS6KA3	S305	N304S	304	Missense	proximal	-1	no	1.964	1.992	EPSD	COSMIC	1.803	Up-regulation
AGC_RSK_RSKp90_RPS6KA3_ST	P03372	ESR1	P51812	RPS6KA3	S305	R300C	300	Missense	distal	-5	no	1.964	1.563	EPSD	COSMIC;CCLE	1.803	Loss
AGC_RSK_RSKp90_RPS6KA3_ST	P03372	ESR1	P51812	RPS6KA3	S305	A307P	307	Missense	proximal	2	no	1.964	1.952	EPSD	COSMIC	1.803	Down-regulation
AGC_RSK_RSKp90_RPS6KA3_ST	P03372	ESR1	P51812	RPS6KA3	S305	N304H	304	Missense	proximal	-1	no	1.964	1.953	EPSD	COSMIC	1.803	Down-regulation
AGC_RSK_RSKp90_RPS6KA3_ST	P03372	ESR1	P51812	RPS6KA3	S341	S338R	338	Missense	distal	-3	no	1.681	3.689	EPSD	COSMIC	1.803	Gain
AGC_RSK_RSKp90_RPS6KA3_ST	P03372	ESR1	P51812	RPS6KA3	S559	G557R	557	Missense	proximal	-2	no	1.495	2.028	EPSD	COSMIC	1.803	Gain
AGC_RSK_RSKp90_RPS6KA3_ST	P62753	RPS6	P51812	RPS6KA3	T34	M32L	32	Missense	proximal	-2	no	2.055	2.053	EPSD	COSMIC	1.803	Down-regulation
AGC_RSK_RSKp90_RPS6KA3_ST	P62753	RPS6	P51812	RPS6KA3	T34	F27L	27	Missense	distal	-7	no	2.055	2.049	EPSD	COSMIC	1.803	Down-regulation
AGC_RSK_RSKp90_RPS6KA3_ST	P62753	RPS6	P51812	RPS6KA3	T181	I176V	176	Missense	distal	-5	no	1.930	1.869	EPSD	COSMIC	1.803	Down-regulation
AGC_RSK_RSKp90_RPS6KA3_ST	P67809	YBX1	P51812	RPS6KA3	S102	T108I	108	Missense	distal	6	no	1.917	1.932	PhosphoSitePlus	COSMIC	1.803	Up-regulation
AGC_RSK_RSKp90_RPS6KA3_ST	Q9BSI4	TINF2	P51812	RPS6KA3	S324	M318I	318	Missense	distal	-6	no	3.280	3.273	EPSD	COSMIC	1.803	Down-regulation
AGC_RSK_RSKp90_RPS6KA3_ST	Q9NYV6	RRN3	P51812	RPS6KA3	S17	P11S	11	Missense	distal	-6	no	1.842	1.859	EPSD	COSMIC	1.803	Up-regulation
AGC_RSK_RSKp90_RPS6KA3_ST	Q9NYV6	RRN3	P51812	RPS6KA3	S17	G12E	12	Missense	distal	-5	no	1.842	1.840	EPSD	COSMIC	1.803	Down-regulation
AGC_RSK_RSKp90_RPS6KA3_ST	Q9NYV6	RRN3	P51812	RPS6KA3	S635	T629M	629	Missense	distal	-6	no	3.682	3.693	EPSD	COSMIC	1.803	Up-regulation
AGC_RSK_RSKp90_RPS6KA3_ST	P13796	LCP1	P51812	RPS6KA3	S5	D8N	8	Missense	distal	3	no	2.014	2.013	PhosphoSitePlus	COSMIC	1.803	Down-regulation
AGC_RSK_RSKp90_RPS6KA3_ST	P13796	LCP1	P51812	RPS6KA3	S5	E9D	9	Missense	distal	4	no	2.014	2.031	PhosphoSitePlus	COSMIC	1.803	Up-regulation
AGC_RSK_RSKp90_RPS6KA3_ST	P13796	LCP1	P51812	RPS6KA3	T54	V50I	50	Missense	distal	-4	no	2.019	2.050	EPSD	COSMIC	1.803	Up-regulation
AGC_RSK_RSKp90_RPS6KA3_ST	P13796	LCP1	P51812	RPS6KA3	T54	R49G	49	Missense	distal	-5	no	2.019	1.651	EPSD	COSMIC	1.803	Loss
AGC_RSK_RSKp90_RPS6KA3_ST	P13796	LCP1	P51812	RPS6KA3	S202	G205W	205	Missense	distal	3	no	1.948	1.947	EPSD	COSMIC	1.803	Down-regulation
AGC_RSK_RSKp90_RPS6KA3_ST	P13796	LCP1	P51812	RPS6KA3	S202	A197S	197	Missense	distal	-5	no	1.948	1.945	EPSD	COSMIC	1.803	Down-regulation
AGC_RSK_RSKp90_RPS6KA3_ST	P13796	LCP1	P51812	RPS6KA3	S202	L196V	196	Missense	distal	-6	no	1.948	1.938	EPSD	COSMIC	1.803	Down-regulation
AGC_RSK_RSKp90_RPS6KA3_ST	P13796	LCP1	P51812	RPS6KA3	T503	L507I	507	Missense	distal	4	no	2.317	2.306	EPSD	COSMIC	1.803	Down-regulation
AGC_RSK_RSKp90_RPS6KA3_ST	P13796	LCP1	P51812	RPS6KA3	S535	K533E	533	Missense	proximal	-2	no	1.805	1.694	EPSD	COSMIC	1.803	Loss
AGC_RSK_RSKp90_RPS6KA3_ST	P13796	LCP1	P51812	RPS6KA3	S535	K542N	542	Missense	distal	7	no	1.805	1.816	EPSD	COSMIC	1.803	Up-regulation
AGC_RSK_RSKp90_RPS6KA3_ST	P13796	LCP1	P51812	RPS6KA3	S536	K533E	533	Missense	distal	-3	no	1.826	1.352	EPSD	COSMIC	1.803	Loss
AGC_RSK_RSKp90_RPS6KA3_ST	P13796	LCP1	P51812	RPS6KA3	S536	K542N	542	Missense	distal	6	no	1.826	1.812	EPSD	COSMIC	1.803	Down-regulation
AGC_RSK_RSKp90_RPS6KA3_ST	P13796	LCP1	P51812	RPS6KA3	S537	K533E	533	Missense	distal	-4	no	1.846	1.803	EPSD	COSMIC	1.803	Down-regulation
AGC_RSK_RSKp90_RPS6KA3_ST	P13796	LCP1	P51812	RPS6KA3	S537	K542N	542	Missense	distal	5	no	1.846	1.872	EPSD	COSMIC	1.803	Up-regulation
AGC_RSK_RSKp90_RPS6KA3_ST	P13796	LCP1	P51812	RPS6KA3	S539	K533E	533	Missense	distal	-6	no	2.264	2.244	EPSD	COSMIC	1.803	Down-regulation
AGC_RSK_RSKp90_RPS6KA3_ST	P13796	LCP1	P51812	RPS6KA3	S539	K542N	542	Missense	distal	3	no	2.264	2.267	EPSD	COSMIC	1.803	Up-regulation
AGC_RSK_RSKp90_RPS6KA3_ST	P19105	MYL12A	P51812	RPS6KA3	T10	K7R	7	Missense	distal	-3	no	0.353	2.320	EPSD	COSMIC	1.803	Gain
AGC_RSK_RSKp90_RPS6KA3_ST	P19105	MYL12A	P51812	RPS6KA3	S19	P14H	14	Missense	distal	-5	no	3.466	3.407	PhosphoSitePlus	COSMIC	1.803	Down-regulation
AGC_RSK_RSKp90_RPS6KA3_ST	P19105	MYL12A	P51812	RPS6KA3	S19	R16C	16	Missense	distal	-3	no	3.466	0.856	PhosphoSitePlus	COSMIC;GDSC;CCLE	1.803	Loss
AGC_RSK_RSKp90_RPS6KA3_ST	P19105	MYL12A	P51812	RPS6KA3	S19	R16H	16	Missense	distal	-3	no	3.466	0.928	PhosphoSitePlus	COSMIC;GDSC;CCLE	1.803	Loss
AGC_RSK_RSKp90_RPS6KA3_ST	P19105	MYL12A	P51812	RPS6KA3	S19	A17S	17	Missense	proximal	-2	no	3.466	3.504	PhosphoSitePlus	COSMIC	1.803	Up-regulation
AGC_RSK_RSKp90_RPS6KA3_ST	P19105	MYL12A	P51812	RPS6KA3	S19	R13H	13	Missense	distal	-6	no	3.466	3.387	PhosphoSitePlus	COSMIC	1.803	Down-regulation
AGC_RSK_RSKp90_RPS6KA3_ST	Q9UL17	TBX21	P51812	RPS6KA3	S394	G388E	388	Missense	distal	-6	no	3.886	3.893	EPSD	COSMIC;CCLE	1.803	Up-regulation
AGC_RSK_RSKp90_RPS6KA3_ST	Q9UL17	TBX21	P51812	RPS6KA3	S394	E396K	396	Missense	proximal	2	no	3.886	3.910	EPSD	COSMIC	1.803	Up-regulation
AGC_RSK_RSKp90_RPS6KA3_ST	Q9UL17	TBX21	P51812	RPS6KA3	S394	H393N	393	Missense	proximal	-1	no	3.886	3.896	EPSD	COSMIC	1.803	Up-regulation
AGC_RSK_RSKp90_RPS6KA3_ST	Q9UL17	TBX21	P51812	RPS6KA3	S403	E396K	396	Missense	distal	-7	no	3.868	3.863	EPSD	COSMIC	1.803	Down-regulation
AGC_RSK_RSKp90_RPS6KA3_ST	Q9UL17	TBX21	P51812	RPS6KA3	S503	R501S	501	Missense	proximal	-2	no	4.048	3.632	PhosphoSitePlus;EPSD	COSMIC	1.803	Down-regulation
AGC_RSK_RSKp90_RPS6KA3_ST	Q9UL17	TBX21	P51812	RPS6KA3	S503	R500M	500	Missense	distal	-3	no	4.048	1.731	PhosphoSitePlus;EPSD	COSMIC	1.803	Loss
AGC_RSK_RSKp90_RPS6KA3_ST	Q9UL17	TBX21	P51812	RPS6KA3	S503	V502M	502	Missense	proximal	-1	no	4.048	4.067	PhosphoSitePlus;EPSD	COSMIC	1.803	Up-regulation
AGC_RSK_RSKp90_RPS6KA3_ST	Q9UL17	TBX21	P51812	RPS6KA3	S503	S503F	503	Missense	central	0	yes	4.048	0.000	PhosphoSitePlus;EPSD	COSMIC	1.803	Loss
AGC_RSK_RSKp90_RPS6KA3_ST	Q9UL17	TBX21	P51812	RPS6KA3	S507	R501S	501	Missense	distal	-6	no	1.879	1.831	EPSD;PhosphoSitePlus	COSMIC	1.803	Down-regulation
AGC_RSK_RSKp90_RPS6KA3_ST	Q9UL17	TBX21	P51812	RPS6KA3	S507	R500M	500	Missense	distal	-7	no	1.879	1.902	EPSD;PhosphoSitePlus	COSMIC	1.803	Up-regulation
AGC_RSK_RSKp90_RPS6KA3_ST	Q9UL17	TBX21	P51812	RPS6KA3	S507	S513F	513	Missense	distal	6	no	1.879	1.811	EPSD;PhosphoSitePlus	COSMIC	1.803	Down-regulation
AGC_RSK_RSKp90_RPS6KA3_ST	Q9UL17	TBX21	P51812	RPS6KA3	S507	V502M	502	Missense	distal	-5	no	1.879	1.963	EPSD;PhosphoSitePlus	COSMIC	1.803	Up-regulation
AGC_RSK_RSKp90_RPS6KA3_ST	Q9UL17	TBX21	P51812	RPS6KA3	S507	S503F	503	Missense	distal	-4	no	1.879	1.736	EPSD;PhosphoSitePlus	COSMIC	1.803	Loss
AGC_RSK_RSKp90_RPS6KA3_ST	P53355	DAPK1	P51812	RPS6KA3	S57	R63Q	63	Missense	distal	6	no	3.715	3.659	EPSD	COSMIC	1.803	Down-regulation
AGC_RSK_RSKp90_RPS6KA3_ST	P53355	DAPK1	P51812	RPS6KA3	S57	G55D	55	Missense	proximal	-2	no	3.715	3.675	EPSD	COSMIC	1.803	Down-regulation
AGC_RSK_RSKp90_RPS6KA3_ST	P53355	DAPK1	P51812	RPS6KA3	S66	R63Q	63	Missense	distal	-3	no	3.996	1.489	EPSD	COSMIC	1.803	Loss
AGC_RSK_RSKp90_RPS6KA3_ST	P53355	DAPK1	P51812	RPS6KA3	S289	A288T	288	Missense	proximal	-1	no	4.083	4.054	PhosphoSitePlus	COSMIC	1.803	Down-regulation
AGC_RSK_RSKp90_RPS6KA3_ST	P53355	DAPK1	P51812	RPS6KA3	S289	V291A	291	Missense	proximal	2	no	4.083	4.138	PhosphoSitePlus	COSMIC	1.803	Up-regulation
AGC_RSK_RSKp90_RPS6KA3_ST	P53355	DAPK1	P51812	RPS6KA3	S313	V309I	309	Missense	distal	-4	no	3.844	3.875	EPSD	COSMIC	1.803	Up-regulation
AGC_RSK_RSKp90_RPS6KA3_ST	P53355	DAPK1	P51812	RPS6KA3	S313	R310H	310	Missense	distal	-3	no	3.844	1.306	EPSD	COSMIC	1.803	Loss
AGC_RSK_RSKp90_RPS6KA3_ST	P53355	DAPK1	P51812	RPS6KA3	S724	R730K	730	Missense	distal	6	no	2.514	2.470	EPSD	COSMIC	1.803	Down-regulation
AGC_RSK_RSKp90_RPS6KA3_ST	P53355	DAPK1	P51812	RPS6KA3	S724	R720Q	720	Missense	distal	-4	no	2.514	2.349	EPSD	COSMIC	1.803	Down-regulation
AGC_RSK_RSKp90_RPS6KA3_ST	P53355	DAPK1	P51812	RPS6KA3	S725	R730K	730	Missense	distal	5	no	3.723	3.774	EPSD	COSMIC	1.803	Up-regulation
AGC_RSK_RSKp90_RPS6KA3_ST	P53355	DAPK1	P51812	RPS6KA3	S725	R720Q	720	Missense	distal	-5	no	3.723	3.360	EPSD	COSMIC	1.803	Down-regulation
AGC_RSK_RSKp90_RPS6KA3_ST	P53355	DAPK1	P51812	RPS6KA3	S728	R730K	730	Missense	proximal	2	no	1.910	1.848	EPSD	COSMIC	1.803	Down-regulation
AGC_RSK_RSKp90_RPS6KA3_ST	P53355	DAPK1	P51812	RPS6KA3	S728	P733L	733	Missense	distal	5	no	1.910	1.949	EPSD	COSMIC	1.803	Up-regulation
AGC_RSK_RSKp90_RPS6KA3_ST	P53355	DAPK1	P51812	RPS6KA3	S762	P767L	767	Missense	distal	5	no	3.212	3.250	EPSD	COSMIC	1.803	Up-regulation
AGC_RSK_RSKp90_RPS6KA3_ST	P53355	DAPK1	P51812	RPS6KA3	S762	M764V	764	Missense	proximal	2	no	3.212	3.178	EPSD	COSMIC	1.803	Down-regulation
AGC_RSK_RSKp90_RPS6KA3_ST	P53355	DAPK1	P51812	RPS6KA3	S762	F765S	765	Missense	distal	3	no	3.212	3.202	EPSD	COSMIC	1.803	Down-regulation
AGC_RSK_RSKp90_RPS6KA3_ST	P53355	DAPK1	P51812	RPS6KA3	S762	R761C	761	Missense	proximal	-1	no	3.212	3.138	EPSD	COSMIC	1.803	Down-regulation
AGC_RSK_RSKp90_RPS6KA3_ST	Q16821	PPP1R3A	P51812	RPS6KA3	S46	P39R	39	Missense	distal	-7	no	4.523	4.503	PhosphoSitePlus;EPSD	COSMIC;GDSC;CCLE	1.803	Down-regulation
AGC_RSK_RSKp90_RPS6KA3_ST	Q16821	PPP1R3A	P51812	RPS6KA3	S46	G45S	45	Missense	proximal	-1	no	4.523	4.560	PhosphoSitePlus;EPSD	COSMIC	1.803	Up-regulation
AGC_RSK_RSKp90_RPS6KA3_ST	Q16821	PPP1R3A	P51812	RPS6KA3	S46	R44L	44	Missense	proximal	-2	no	4.523	4.017	PhosphoSitePlus;EPSD	COSMIC	1.803	Down-regulation
AGC_RSK_RSKp90_RPS6KA3_ST	Q16821	PPP1R3A	P51812	RPS6KA3	S46	S42C	42	Missense	distal	-4	no	4.523	4.420	PhosphoSitePlus;EPSD	COSMIC	1.803	Down-regulation
AGC_RSK_RSKp90_RPS6KA3_ST	Q16821	PPP1R3A	P51812	RPS6KA3	S48	G45S	45	Missense	distal	-3	no	1.929	2.303	EPSD	COSMIC	1.803	Up-regulation
AGC_RSK_RSKp90_RPS6KA3_ST	Q16821	PPP1R3A	P51812	RPS6KA3	S48	R44L	44	Missense	distal	-4	no	1.929	1.741	EPSD	COSMIC	1.803	Loss
AGC_RSK_RSKp90_RPS6KA3_ST	Q16821	PPP1R3A	P51812	RPS6KA3	S48	S42C	42	Missense	distal	-6	no	1.929	1.890	EPSD	COSMIC	1.803	Down-regulation
AGC_RSK_RSKp90_RPS6KA3_ST	Q16821	PPP1R3A	P51812	RPS6KA3	S49	G45S	45	Missense	distal	-4	no	1.834	1.913	EPSD	COSMIC	1.803	Up-regulation
AGC_RSK_RSKp90_RPS6KA3_ST	Q16821	PPP1R3A	P51812	RPS6KA3	S49	R44L	44	Missense	distal	-5	no	1.834	1.488	EPSD	COSMIC	1.803	Loss
AGC_RSK_RSKp90_RPS6KA3_ST	Q16821	PPP1R3A	P51812	RPS6KA3	S49	S42C	42	Missense	distal	-7	no	1.834	1.852	EPSD	COSMIC	1.803	Up-regulation
AGC_RSK_RSKp90_RPS6KA3_ST	Q16821	PPP1R3A	P51812	RPS6KA3	S65	S65L	65	Missense	central	0	yes	4.168	0.000	EPSD;PhosphoSitePlus	COSMIC;CCLE	1.803	Loss
AGC_RSK_RSKp90_RPS6KA3_ST	Q16821	PPP1R3A	P51812	RPS6KA3	S65	G60V	60	Missense	distal	-5	no	4.168	4.107	EPSD;PhosphoSitePlus	COSMIC	1.803	Down-regulation
AGC_RSK_RSKp90_RPS6KA3_ST	Q16821	PPP1R3A	P51812	RPS6KA3	S65	R62G	62	Missense	distal	-3	no	4.168	1.786	EPSD;PhosphoSitePlus	COSMIC	1.803	Loss
AGC_RSK_RSKp90_RPS6KA3_ST	Q16821	PPP1R3A	P51812	RPS6KA3	S65	A67V	67	Missense	proximal	2	no	4.168	4.112	EPSD;PhosphoSitePlus	COSMIC	1.803	Down-regulation
AGC_RSK_RSKp90_RPS6KA3_ST	Q16821	PPP1R3A	P51812	RPS6KA3	S65	D68N	68	Missense	distal	3	no	4.168	4.166	EPSD;PhosphoSitePlus	COSMIC	1.803	Down-regulation
AGC_RSK_RSKp90_RPS6KA3_ST	Q16821	PPP1R3A	P51812	RPS6KA3	S332	E338K	338	Missense	distal	6	no	3.566	3.580	EPSD	COSMIC	1.803	Up-regulation
AGC_RSK_RSKp90_RPS6KA3_ST	Q16821	PPP1R3A	P51812	RPS6KA3	S332	A334S	334	Missense	proximal	2	no	3.566	3.626	EPSD	COSMIC	1.803	Up-regulation
AGC_RSK_RSKp90_RPS6KA3_ST	Q16821	PPP1R3A	P51812	RPS6KA3	S332	T330N	330	Missense	proximal	-2	no	3.566	3.651	EPSD	COSMIC;CCLE	1.803	Up-regulation
AGC_RSK_RSKp90_RPS6KA3_ST	Q16821	PPP1R3A	P51812	RPS6KA3	S332	I328V	328	Missense	distal	-4	no	3.566	3.535	EPSD	COSMIC	1.803	Down-regulation
AGC_RSK_RSKp90_RPS6KA3_ST	Q16821	PPP1R3A	P51812	RPS6KA3	S332	D337N	337	Missense	distal	5	no	3.566	3.546	EPSD	COSMIC	1.803	Down-regulation
AGC_RSK_RSKp90_RPS6KA3_ST	Q16821	PPP1R3A	P51812	RPS6KA3	S375	S377R	377	Missense	proximal	2	no	3.509	3.516	EPSD	COSMIC;GDSC	1.803	Up-regulation
AGC_RSK_RSKp90_RPS6KA3_ST	Q16821	PPP1R3A	P51812	RPS6KA3	S375	S379P	379	Missense	distal	4	no	3.509	3.548	EPSD	COSMIC	1.803	Up-regulation
AGC_RSK_RSKp90_RPS6KA3_ST	Q16821	PPP1R3A	P51812	RPS6KA3	S375	D368E	368	Missense	distal	-7	no	3.509	3.502	EPSD	COSMIC	1.803	Down-regulation
AGC_RSK_RSKp90_RPS6KA3_ST	Q16821	PPP1R3A	P51812	RPS6KA3	S377	S377R	377	Missense	central	0	yes	2.147	0.000	EPSD	COSMIC;GDSC	1.803	Loss
AGC_RSK_RSKp90_RPS6KA3_ST	Q16821	PPP1R3A	P51812	RPS6KA3	S377	S379P	379	Missense	proximal	2	no	2.147	2.076	EPSD	COSMIC	1.803	Down-regulation
AGC_RSK_RSKp90_RPS6KA3_ST	Q16821	PPP1R3A	P51812	RPS6KA3	T578	S582F	582	Missense	distal	4	no	1.750	1.831	EPSD	COSMIC;GDSC;CCLE	1.803	Gain
AGC_RSK_RSKp90_RPS6KA3_ST	Q16821	PPP1R3A	P51812	RPS6KA3	S737	K734R	734	Missense	distal	-3	no	1.625	3.592	EPSD	COSMIC	1.803	Gain
AGC_RSK_RSKp90_RPS6KA3_ST	Q16821	PPP1R3A	P51812	RPS6KA3	S743	E738A	738	Missense	distal	-5	no	1.755	1.811	EPSD	COSMIC	1.803	Gain
AGC_RSK_RSKp90_RPS6KA3_ST	P18848	ATF4	P51812	RPS6KA3	S74	G81E	81	Missense	distal	7	no	1.839	1.828	EPSD	COSMIC	1.803	Down-regulation
AGC_RSK_RSKp90_RPS6KA3_ST	P18848	ATF4	P51812	RPS6KA3	S74	S71A	71	Missense	distal	-3	no	1.839	1.735	EPSD	COSMIC	1.803	Loss
AGC_RSK_RSKp90_RPS6KA3_ST	P18848	ATF4	P51812	RPS6KA3	S74	S69I	69	Missense	distal	-5	no	1.839	1.786	EPSD	COSMIC	1.803	Loss
AGC_RSK_RSKp90_RPS6KA3_ST	P32314	FOXN2	P51812	RPS6KA3	T15	A18V	18	Missense	distal	3	no	1.918	1.923	EPSD	COSMIC	1.803	Up-regulation
AGC_RSK_RSKp90_RPS6KA3_ST	P32314	FOXN2	P51812	RPS6KA3	T15	R12G	12	Missense	distal	-3	no	1.918	-0.464	EPSD	COSMIC	1.803	Loss
AGC_RSK_RSKp90_RPS6KA3_ST	P32314	FOXN2	P51812	RPS6KA3	T15	R12K	12	Missense	distal	-3	no	1.918	-0.049	EPSD	COSMIC	1.803	Loss
AGC_RSK_RSKp90_RPS6KA3_ST	P32314	FOXN2	P51812	RPS6KA3	T15	A13S	13	Missense	proximal	-2	no	1.918	1.956	EPSD	COSMIC	1.803	Up-regulation
AGC_RSK_RSKp90_RPS6KA3_ST	P32314	FOXN2	P51812	RPS6KA3	S318	S322F	322	Missense	distal	4	no	1.742	1.823	EPSD	COSMIC	1.803	Gain
AGC_RSK_RSKp90_RPS6KA3_ST	P40763	STAT3	P51812	RPS6KA3	S599	R595L	595	Missense	distal	-4	no	1.954	1.766	EPSD	COSMIC	1.803	Loss
AGC_RSK_RSKp90_RPS6KA3_ST	P40763	STAT3	P51812	RPS6KA3	S691	D698N	698	Missense	distal	7	no	3.562	3.549	EPSD	COSMIC	1.803	Down-regulation
AGC_RSK_RSKp90_RPS6KA3_ST	P40763	STAT3	P51812	RPS6KA3	S691	G684R	684	Missense	distal	-7	no	3.562	3.535	EPSD	COSMIC	1.803	Down-regulation
AGC_RSK_RSKp90_RPS6KA3_ST	P40763	STAT3	P51812	RPS6KA3	S701	D698N	698	Missense	distal	-3	no	1.478	1.925	EPSD	COSMIC	1.803	Gain
AGC_RSK_RSKp90_RPS6KA3_ST	P40763	STAT3	P51812	RPS6KA3	S727	D723N	723	Missense	distal	-4	no	2.103	2.141	PhosphoSitePlus	COSMIC	1.803	Up-regulation
AGC_RSK_RSKp90_RPS6KA3_ST	P11362	FGFR1	P51812	RPS6KA3	T428	I421V	421	Missense	distal	-7	no	2.143	2.147	EPSD	COSMIC;GDSC;CCLE	1.803	Up-regulation
AGC_RSK_RSKp90_RPS6KA3_ST	P11362	FGFR1	P51812	RPS6KA3	T428	S430F	430	Missense	proximal	2	no	2.143	2.011	EPSD	COSMIC	1.803	Down-regulation
AGC_RSK_RSKp90_RPS6KA3_ST	P11362	FGFR1	P51812	RPS6KA3	T428	S434N	434	Missense	distal	6	no	2.143	2.103	EPSD	COSMIC	1.803	Down-regulation
AGC_RSK_RSKp90_RPS6KA3_ST	P11362	FGFR1	P51812	RPS6KA3	T428	P422S	422	Missense	distal	-6	no	2.143	2.159	EPSD	COSMIC	1.803	Up-regulation
AGC_RSK_RSKp90_RPS6KA3_ST	P11362	FGFR1	P51812	RPS6KA3	T428	A431T	431	Missense	distal	3	no	2.143	2.147	EPSD	COSMIC	1.803	Up-regulation
AGC_RSK_RSKp90_RPS6KA3_ST	P11362	FGFR1	P51812	RPS6KA3	T428	A431S	431	Missense	distal	3	no	2.143	2.139	EPSD	COSMIC	1.803	Down-regulation
AGC_RSK_RSKp90_RPS6KA3_ST	P11362	FGFR1	P51812	RPS6KA3	S439	S436F	436	Missense	distal	-3	no	1.931	1.078	EPSD	COSMIC	1.803	Loss
AGC_RSK_RSKp90_RPS6KA3_ST	P11362	FGFR1	P51812	RPS6KA3	S439	R445W	445	Missense	distal	6	no	1.931	1.862	EPSD	COSMIC	1.803	Down-regulation
AGC_RSK_RSKp90_RPS6KA3_ST	P11362	FGFR1	P51812	RPS6KA3	S439	R445Q	445	Missense	distal	6	no	1.931	1.874	EPSD	COSMIC	1.803	Down-regulation
AGC_RSK_RSKp90_RPS6KA3_ST	P11362	FGFR1	P51812	RPS6KA3	S439	S434N	434	Missense	distal	-5	no	1.931	1.927	EPSD	COSMIC	1.803	Down-regulation
AGC_RSK_RSKp90_RPS6KA3_ST	P11362	FGFR1	P51812	RPS6KA3	S439	R445L	445	Missense	distal	6	no	1.931	1.859	EPSD	COSMIC	1.803	Down-regulation
AGC_RSK_RSKp90_RPS6KA3_ST	P11362	FGFR1	P51812	RPS6KA3	S450	S451F	451	Missense	proximal	1	no	2.632	2.716	EPSD	COSMIC	1.803	Up-regulation
AGC_RSK_RSKp90_RPS6KA3_ST	P11362	FGFR1	P51812	RPS6KA3	S450	R448Q	448	Missense	proximal	-2	no	2.632	2.107	EPSD	COSMIC	1.803	Down-regulation
AGC_RSK_RSKp90_RPS6KA3_ST	P11362	FGFR1	P51812	RPS6KA3	S450	S451C	451	Missense	proximal	1	no	2.632	2.691	EPSD	COSMIC	1.803	Up-regulation
AGC_RSK_RSKp90_RPS6KA3_ST	P11362	FGFR1	P51812	RPS6KA3	S450	R445W	445	Missense	distal	-5	no	2.632	2.250	EPSD	COSMIC	1.803	Down-regulation
AGC_RSK_RSKp90_RPS6KA3_ST	P11362	FGFR1	P51812	RPS6KA3	S450	R445Q	445	Missense	distal	-5	no	2.632	2.270	EPSD	COSMIC	1.803	Down-regulation
AGC_RSK_RSKp90_RPS6KA3_ST	P11362	FGFR1	P51812	RPS6KA3	S450	T454N	454	Missense	distal	4	no	2.632	2.601	EPSD	COSMIC	1.803	Down-regulation
AGC_RSK_RSKp90_RPS6KA3_ST	P11362	FGFR1	P51812	RPS6KA3	S450	S447P	447	Missense	distal	-3	no	2.632	2.525	EPSD	COSMIC	1.803	Down-regulation
AGC_RSK_RSKp90_RPS6KA3_ST	P11362	FGFR1	P51812	RPS6KA3	S450	M456I	456	Missense	distal	6	no	2.632	2.625	EPSD	COSMIC;GDSC	1.803	Down-regulation
AGC_RSK_RSKp90_RPS6KA3_ST	P11362	FGFR1	P51812	RPS6KA3	S450	M456V	456	Missense	distal	6	no	2.632	2.614	EPSD	COSMIC	1.803	Down-regulation
AGC_RSK_RSKp90_RPS6KA3_ST	P11362	FGFR1	P51812	RPS6KA3	S450	S447L	447	Missense	distal	-3	no	2.632	2.409	EPSD	COSMIC	1.803	Down-regulation
AGC_RSK_RSKp90_RPS6KA3_ST	P11362	FGFR1	P51812	RPS6KA3	S450	R448L	448	Missense	proximal	-2	no	2.632	2.126	EPSD	COSMIC	1.803	Down-regulation
AGC_RSK_RSKp90_RPS6KA3_ST	P11362	FGFR1	P51812	RPS6KA3	S450	R445L	445	Missense	distal	-5	no	2.632	2.286	EPSD	COSMIC	1.803	Down-regulation
AGC_RSK_RSKp90_RPS6KA3_ST	P11362	FGFR1	P51812	RPS6KA3	S450	L457R	457	Missense	distal	7	no	2.632	2.576	EPSD	COSMIC	1.803	Down-regulation
AGC_RSK_RSKp90_RPS6KA3_ST	P11362	FGFR1	P51812	RPS6KA3	S451	S451F	451	Missense	central	0	yes	4.041	0.000	EPSD	COSMIC	1.803	Loss
AGC_RSK_RSKp90_RPS6KA3_ST	P11362	FGFR1	P51812	RPS6KA3	S451	R448Q	448	Missense	distal	-3	no	4.041	1.534	EPSD	COSMIC	1.803	Loss
AGC_RSK_RSKp90_RPS6KA3_ST	P11362	FGFR1	P51812	RPS6KA3	S451	S451C	451	Missense	central	0	yes	4.041	0.000	EPSD	COSMIC	1.803	Loss
AGC_RSK_RSKp90_RPS6KA3_ST	P11362	FGFR1	P51812	RPS6KA3	S451	R445W	445	Missense	distal	-6	no	4.041	3.961	EPSD	COSMIC	1.803	Down-regulation
AGC_RSK_RSKp90_RPS6KA3_ST	P11362	FGFR1	P51812	RPS6KA3	S451	R445Q	445	Missense	distal	-6	no	4.041	3.974	EPSD	COSMIC	1.803	Down-regulation
AGC_RSK_RSKp90_RPS6KA3_ST	P11362	FGFR1	P51812	RPS6KA3	S451	T454N	454	Missense	distal	3	no	4.041	4.038	EPSD	COSMIC	1.803	Down-regulation
AGC_RSK_RSKp90_RPS6KA3_ST	P11362	FGFR1	P51812	RPS6KA3	S451	S447P	447	Missense	distal	-4	no	4.041	3.985	EPSD	COSMIC	1.803	Down-regulation
AGC_RSK_RSKp90_RPS6KA3_ST	P11362	FGFR1	P51812	RPS6KA3	S451	M456I	456	Missense	distal	5	no	4.041	4.053	EPSD	COSMIC;GDSC	1.803	Up-regulation
AGC_RSK_RSKp90_RPS6KA3_ST	P11362	FGFR1	P51812	RPS6KA3	S451	M456V	456	Missense	distal	5	no	4.041	4.071	EPSD	COSMIC	1.803	Up-regulation
AGC_RSK_RSKp90_RPS6KA3_ST	P11362	FGFR1	P51812	RPS6KA3	S451	S447L	447	Missense	distal	-4	no	4.041	3.948	EPSD	COSMIC	1.803	Down-regulation
AGC_RSK_RSKp90_RPS6KA3_ST	P11362	FGFR1	P51812	RPS6KA3	S451	R448L	448	Missense	distal	-3	no	4.041	1.810	EPSD	COSMIC	1.803	Down-regulation
AGC_RSK_RSKp90_RPS6KA3_ST	P11362	FGFR1	P51812	RPS6KA3	S451	R445L	445	Missense	distal	-6	no	4.041	3.958	EPSD	COSMIC	1.803	Down-regulation
AGC_RSK_RSKp90_RPS6KA3_ST	P11362	FGFR1	P51812	RPS6KA3	S451	L457R	457	Missense	distal	6	no	4.041	4.112	EPSD	COSMIC	1.803	Up-regulation
AGC_RSK_RSKp90_RPS6KA3_ST	P11362	FGFR1	P51812	RPS6KA3	S786	S779C	779	Missense	distal	-7	no	1.919	1.937	EPSD	COSMIC	1.803	Up-regulation
AGC_RSK_RSKp90_RPS6KA3_ST	P11362	FGFR1	P51812	RPS6KA3	S786	G791E	791	Missense	distal	5	no	1.919	1.893	EPSD	COSMIC	1.803	Down-regulation
AGC_RSK_RSKp90_RPS6KA3_ST	P11362	FGFR1	P51812	RPS6KA3	S786	R784Q	784	Missense	proximal	-2	no	1.919	1.394	EPSD	COSMIC	1.803	Loss
AGC_RSK_RSKp90_RPS6KA3_ST	P11362	FGFR1	P51812	RPS6KA3	S786	R784W	784	Missense	proximal	-2	no	1.919	1.361	EPSD	COSMIC	1.803	Loss
AGC_RSK_RSKp90_RPS6KA3_ST	P11362	FGFR1	P51812	RPS6KA3	S786	S789C	789	Missense	distal	3	no	1.919	1.927	EPSD	COSMIC	1.803	Up-regulation
AGC_RSK_RSKp90_RPS6KA3_ST	P11362	FGFR1	P51812	RPS6KA3	S786	D782N	782	Missense	distal	-4	no	1.919	1.957	EPSD	COSMIC	1.803	Up-regulation
AGC_RSK_RSKp90_RPS6KA3_ST	P11362	FGFR1	P51812	RPS6KA3	S786	S790P	790	Missense	distal	4	no	1.919	1.958	EPSD	COSMIC	1.803	Up-regulation
AGC_RSK_RSKp90_RPS6KA3_ST	P11362	FGFR1	P51812	RPS6KA3	T787	S794F	794	Missense	distal	7	no	1.784	1.842	EPSD	COSMIC	1.803	Gain
AGC_RSK_RSKp90_RPS6KA3_ST	P11362	FGFR1	P51812	RPS6KA3	T787	D782N	782	Missense	distal	-5	no	1.784	1.858	EPSD	COSMIC	1.803	Gain
AGC_RSK_RSKp90_RPS6KA3_ST	P11362	FGFR1	P51812	RPS6KA3	S789	G791E	791	Missense	proximal	2	no	1.807	1.812	PhosphoSitePlus	COSMIC	1.803	Up-regulation
AGC_RSK_RSKp90_RPS6KA3_ST	P11362	FGFR1	P51812	RPS6KA3	S789	R784Q	784	Missense	distal	-5	no	1.807	1.444	PhosphoSitePlus	COSMIC	1.803	Loss
AGC_RSK_RSKp90_RPS6KA3_ST	P11362	FGFR1	P51812	RPS6KA3	S789	S794F	794	Missense	distal	5	no	1.807	1.905	PhosphoSitePlus	COSMIC	1.803	Up-regulation
AGC_RSK_RSKp90_RPS6KA3_ST	P11362	FGFR1	P51812	RPS6KA3	S789	V795I	795	Missense	distal	6	no	1.807	1.818	PhosphoSitePlus	COSMIC	1.803	Up-regulation
AGC_RSK_RSKp90_RPS6KA3_ST	P11362	FGFR1	P51812	RPS6KA3	S789	R784W	784	Missense	distal	-5	no	1.807	1.425	PhosphoSitePlus	COSMIC	1.803	Loss
AGC_RSK_RSKp90_RPS6KA3_ST	P11362	FGFR1	P51812	RPS6KA3	S789	S789C	789	Missense	central	0	yes	1.807	0.000	PhosphoSitePlus	COSMIC	1.803	Loss
AGC_RSK_RSKp90_RPS6KA3_ST	P11362	FGFR1	P51812	RPS6KA3	S789	D782N	782	Missense	distal	-7	no	1.807	1.802	PhosphoSitePlus	COSMIC	1.803	Loss
AGC_RSK_RSKp90_RPS6KA3_ST	P11362	FGFR1	P51812	RPS6KA3	S789	S790P	790	Missense	proximal	1	no	1.807	1.846	PhosphoSitePlus	COSMIC	1.803	Up-regulation
AGC_RSK_RSKp90_RPS6KA3_ST	P16949	STMN1	P51812	RPS6KA3	S16	R14C	14	Missense	proximal	-2	no	2.071	1.490	PhosphoSitePlus	COSMIC	1.803	Loss
AGC_RSK_RSKp90_RPS6KA3_ST	P16949	STMN1	P51812	RPS6KA3	S16	Q18E	18	Missense	proximal	2	no	2.071	2.066	PhosphoSitePlus	COSMIC	1.803	Down-regulation
AGC_RSK_RSKp90_RPS6KA3_ST	P16949	STMN1	P51812	RPS6KA3	S63	R61S	61	Missense	proximal	-2	no	4.110	3.695	EPSD	COSMIC	1.803	Down-regulation
AGC_RSK_RSKp90_RPS6KA3_ST	P16949	STMN1	P51812	RPS6KA3	S139	E132K	132	Missense	distal	-7	no	1.844	1.838	EPSD	COSMIC	1.803	Down-regulation
AGC_RSK_RSKp90_RPS6KA3_ST	P16949	STMN1	P51812	RPS6KA3	S139	E145K	145	Missense	distal	6	no	1.844	1.857	EPSD	COSMIC	1.803	Up-regulation
AGC_RSK_RSKp90_RPS6KA3_ST	P29317	EPHA2	P51812	RPS6KA3	S433	R428C	428	Missense	distal	-5	no	1.959	1.558	EPSD	COSMIC;GDSC;CCLE	1.803	Loss
AGC_RSK_RSKp90_RPS6KA3_ST	P29317	EPHA2	P51812	RPS6KA3	S433	V432I	432	Missense	proximal	-1	no	1.959	1.972	EPSD	COSMIC	1.803	Up-regulation
AGC_RSK_RSKp90_RPS6KA3_ST	P29317	EPHA2	P51812	RPS6KA3	S433	R428H	428	Missense	distal	-5	no	1.959	1.576	EPSD	COSMIC	1.803	Loss
AGC_RSK_RSKp90_RPS6KA3_ST	P29317	EPHA2	P51812	RPS6KA3	S636	S635F	635	Missense	proximal	-1	no	1.915	1.855	EPSD	COSMIC	1.803	Down-regulation
AGC_RSK_RSKp90_RPS6KA3_ST	P29317	EPHA2	P51812	RPS6KA3	S897	V904G	904	Missense	distal	7	no	3.710	3.703	PhosphoSitePlus	COSMIC	1.803	Down-regulation
AGC_RSK_RSKp90_RPS6KA3_ST	P29317	EPHA2	P51812	RPS6KA3	S897	R890C	890	Missense	distal	-7	no	3.710	3.737	PhosphoSitePlus	COSMIC	1.803	Up-regulation
AGC_RSK_RSKp90_RPS6KA3_ST	P29317	EPHA2	P51812	RPS6KA3	S897	T898M	898	Missense	proximal	1	no	3.710	3.675	PhosphoSitePlus	COSMIC	1.803	Down-regulation
AGC_RSK_RSKp90_RPS6KA3_ST	P29317	EPHA2	P51812	RPS6KA3	S899	V904G	904	Missense	distal	5	no	2.455	2.446	EPSD	COSMIC	1.803	Down-regulation
AGC_RSK_RSKp90_RPS6KA3_ST	P29317	EPHA2	P51812	RPS6KA3	S899	T898M	898	Missense	proximal	-1	no	2.455	2.471	EPSD	COSMIC	1.803	Up-regulation
AGC_RSK_RSKp90_RPS6KA3_ST	P29317	EPHA2	P51812	RPS6KA3	S910	E911K	911	Missense	proximal	1	no	3.449	3.426	EPSD	COSMIC;CCLE	1.803	Down-regulation
AGC_RSK_RSKp90_RPS6KA3_ST	P29317	EPHA2	P51812	RPS6KA3	S910	V904G	904	Missense	distal	-6	no	3.449	3.461	EPSD	COSMIC	1.803	Up-regulation
AGC_RSK_RSKp90_RPS6KA3_ST	P29317	EPHA2	P51812	RPS6KA3	S910	T908M	908	Missense	proximal	-2	no	3.449	3.495	EPSD	COSMIC	1.803	Up-regulation
AGC_RSK_RSKp90_RPS6KA3_ST	P48764	SLC9A3	P51812	RPS6KA3	S555	E549K	549	Missense	distal	-6	no	3.739	3.759	EPSD	COSMIC	1.803	Up-regulation
AGC_RSK_RSKp90_RPS6KA3_ST	P48764	SLC9A3	P51812	RPS6KA3	S555	I559F	559	Missense	distal	4	no	3.739	3.761	EPSD	COSMIC	1.803	Up-regulation
AGC_RSK_RSKp90_RPS6KA3_ST	P48764	SLC9A3	P51812	RPS6KA3	S555	R552H	552	Missense	distal	-3	no	3.739	1.200	EPSD	COSMIC	1.803	Loss
AGC_RSK_RSKp90_RPS6KA3_ST	P48764	SLC9A3	P51812	RPS6KA3	S555	A548T	548	Missense	distal	-7	no	3.739	3.754	EPSD	COSMIC	1.803	Up-regulation
AGC_RSK_RSKp90_RPS6KA3_ST	P48764	SLC9A3	P51812	RPS6KA3	S563	I559F	559	Missense	distal	-4	no	3.937	3.886	EPSD	COSMIC	1.803	Down-regulation
AGC_RSK_RSKp90_RPS6KA3_ST	P48764	SLC9A3	P51812	RPS6KA3	S663	R658W	658	Missense	distal	-5	no	4.081	3.699	PhosphoSitePlus	COSMIC	1.803	Down-regulation
AGC_RSK_RSKp90_RPS6KA3_ST	P48764	SLC9A3	P51812	RPS6KA3	S693	P695H	695	Missense	proximal	2	no	3.629	3.606	EPSD	COSMIC	1.803	Down-regulation
AGC_RSK_RSKp90_RPS6KA3_ST	P48764	SLC9A3	P51812	RPS6KA3	S693	S693I	693	Missense	central	0	yes	3.629	0.000	EPSD	COSMIC	1.803	Loss
AGC_RSK_RSKp90_RPS6KA3_ST	P48764	SLC9A3	P51812	RPS6KA3	S693	G697W	697	Missense	distal	4	no	3.629	3.622	EPSD	COSMIC	1.803	Down-regulation
AGC_RSK_RSKp90_RPS6KA3_ST	P48764	SLC9A3	P51812	RPS6KA3	S808	R805S	805	Missense	distal	-3	no	4.040	2.033	EPSD	COSMIC	1.803	Down-regulation
AGC_RSK_RSKp90_RPS6KA3_ST	P48764	SLC9A3	P51812	RPS6KA3	S810	R805S	805	Missense	distal	-5	no	2.158	1.841	EPSD	COSMIC	1.803	Down-regulation
AGC_RSK_RSKp90_RPS6KA3_ST	P48764	SLC9A3	P51812	RPS6KA3	S810	A817E	817	Missense	distal	7	no	2.158	2.173	EPSD	COSMIC	1.803	Up-regulation
AGC_RSK_RSKp90_RPS6KA3_ST	P48764	SLC9A3	P51812	RPS6KA3	S831	S831Y	831	Missense	central	0	yes	1.813	0.000	EPSD	COSMIC	1.803	Loss
AGC_RSK_RSKp90_RPS6KA3_ST	Q96RK0	CIC	P51812	RPS6KA3	S12	R6G	6	Missense	distal	-6	no	1.931	1.850	EPSD	COSMIC	1.803	Down-regulation
AGC_RSK_RSKp90_RPS6KA3_ST	Q96RK0	CIC	P51812	RPS6KA3	S12	P10S	10	Missense	proximal	-2	no	1.931	1.986	EPSD	COSMIC	1.803	Up-regulation
AGC_RSK_RSKp90_RPS6KA3_ST	Q96RK0	CIC	P51812	RPS6KA3	S77	E83K	83	Missense	distal	6	no	1.800	1.813	EPSD	COSMIC	1.803	Gain
AGC_RSK_RSKp90_RPS6KA3_ST	Q96RK0	CIC	P51812	RPS6KA3	S77	R84Q	84	Missense	distal	7	no	1.800	1.837	EPSD	COSMIC	1.803	Gain
AGC_RSK_RSKp90_RPS6KA3_ST	Q96RK0	CIC	P51812	RPS6KA3	S77	R84W	84	Missense	distal	7	no	1.800	1.848	EPSD	COSMIC	1.803	Gain
AGC_RSK_RSKp90_RPS6KA3_ST	Q96RK0	CIC	P51812	RPS6KA3	S142	R139Q	139	Missense	distal	-3	no	3.738	1.231	EPSD	COSMIC	1.803	Loss
AGC_RSK_RSKp90_RPS6KA3_ST	Q96RK0	CIC	P51812	RPS6KA3	S142	E137Q	137	Missense	distal	-5	no	3.738	3.745	EPSD	COSMIC	1.803	Up-regulation
AGC_RSK_RSKp90_RPS6KA3_ST	Q96RK0	CIC	P51812	RPS6KA3	S142	P135R	135	Missense	distal	-7	no	3.738	3.718	EPSD	COSMIC	1.803	Down-regulation
AGC_RSK_RSKp90_RPS6KA3_ST	Q96RK0	CIC	P51812	RPS6KA3	S173	R170L	170	Missense	distal	-3	no	3.665	1.435	PhosphoSitePlus	COSMIC	1.803	Loss
AGC_RSK_RSKp90_RPS6KA3_ST	Q96RK0	CIC	P51812	RPS6KA3	S173	G167R	167	Missense	distal	-6	no	3.665	3.746	PhosphoSitePlus	COSMIC	1.803	Up-regulation
AGC_RSK_RSKp90_RPS6KA3_ST	Q96RK0	CIC	P51812	RPS6KA3	S173	S173F	173	Missense	central	0	yes	3.665	0.000	PhosphoSitePlus	COSMIC	1.803	Loss
AGC_RSK_RSKp90_RPS6KA3_ST	Q96RK0	CIC	P51812	RPS6KA3	S173	G167E	167	Missense	distal	-6	no	3.665	3.673	PhosphoSitePlus	COSMIC	1.803	Up-regulation
AGC_RSK_RSKp90_RPS6KA3_ST	Q96RK0	CIC	P51812	RPS6KA3	S173	E180K	180	Missense	distal	7	no	3.665	3.651	PhosphoSitePlus	COSMIC	1.803	Down-regulation
AGC_RSK_RSKp90_RPS6KA3_ST	Q96RK0	CIC	P51812	RPS6KA3	S173	L177I	177	Missense	distal	4	no	3.665	3.654	PhosphoSitePlus	COSMIC	1.803	Down-regulation
AGC_RSK_RSKp90_RPS6KA3_ST	Q96RK0	CIC	P51812	RPS6KA3	S175	R170L	170	Missense	distal	-5	no	1.834	1.488	EPSD	COSMIC	1.803	Loss
AGC_RSK_RSKp90_RPS6KA3_ST	Q96RK0	CIC	P51812	RPS6KA3	S175	S173F	173	Missense	proximal	-2	no	1.834	1.596	EPSD	COSMIC	1.803	Loss
AGC_RSK_RSKp90_RPS6KA3_ST	Q96RK0	CIC	P51812	RPS6KA3	S175	R181L	181	Missense	distal	6	no	1.834	1.762	EPSD	COSMIC	1.803	Loss
AGC_RSK_RSKp90_RPS6KA3_ST	Q96RK0	CIC	P51812	RPS6KA3	S175	E180K	180	Missense	distal	5	no	1.834	1.809	EPSD	COSMIC	1.803	Down-regulation
AGC_RSK_RSKp90_RPS6KA3_ST	Q96RK0	CIC	P51812	RPS6KA3	S175	L177I	177	Missense	proximal	2	no	1.834	1.845	EPSD	COSMIC	1.803	Up-regulation
AGC_RSK_RSKp90_RPS6KA3_ST	Q96RK0	CIC	P51812	RPS6KA3	S231	S231N	231	Missense	central	0	yes	3.134	0.000	EPSD	COSMIC	1.803	Loss
AGC_RSK_RSKp90_RPS6KA3_ST	Q96RK0	CIC	P51812	RPS6KA3	S231	W238C	238	Missense	distal	7	no	3.134	3.140	EPSD	COSMIC	1.803	Up-regulation
AGC_RSK_RSKp90_RPS6KA3_ST	Q96RK0	CIC	P51812	RPS6KA3	S231	D226G	226	Missense	distal	-5	no	3.134	3.160	EPSD	COSMIC	1.803	Up-regulation
AGC_RSK_RSKp90_RPS6KA3_ST	Q96RK0	CIC	P51812	RPS6KA3	S231	D226H	226	Missense	distal	-5	no	3.134	3.145	EPSD	COSMIC	1.803	Up-regulation
AGC_RSK_RSKp90_RPS6KA3_ST	Q96RK0	CIC	P51812	RPS6KA3	S231	K232Q	232	Missense	proximal	1	no	3.134	3.149	EPSD	COSMIC	1.803	Up-regulation
AGC_RSK_RSKp90_RPS6KA3_ST	Q96RK0	CIC	P51812	RPS6KA3	S231	T229I	229	Missense	proximal	-2	no	3.134	3.141	EPSD	COSMIC	1.803	Up-regulation
AGC_RSK_RSKp90_RPS6KA3_ST	Q96RK0	CIC	P51812	RPS6KA3	S231	N227H	227	Missense	distal	-4	no	3.134	3.105	EPSD	COSMIC	1.803	Down-regulation
AGC_RSK_RSKp90_RPS6KA3_ST	Q96RK0	CIC	P51812	RPS6KA3	S231	D226Y	226	Missense	distal	-5	no	3.134	3.137	EPSD	COSMIC	1.803	Up-regulation
AGC_RSK_RSKp90_RPS6KA3_ST	Q96RK0	CIC	P51812	RPS6KA3	S231	R228G	228	Missense	distal	-3	no	3.134	0.752	EPSD	COSMIC	1.803	Loss
AGC_RSK_RSKp90_RPS6KA3_ST	Q96RK0	CIC	P51812	RPS6KA3	S231	W238R	238	Missense	distal	7	no	3.134	3.086	EPSD	COSMIC	1.803	Down-regulation
AGC_RSK_RSKp90_RPS6KA3_ST	Q96RK0	CIC	P51812	RPS6KA3	S231	E236K	236	Missense	distal	5	no	3.134	3.110	EPSD	COSMIC	1.803	Down-regulation
AGC_RSK_RSKp90_RPS6KA3_ST	Q96RK0	CIC	P51812	RPS6KA3	S277	D273E	273	Missense	distal	-4	no	4.091	4.119	EPSD	COSMIC	1.803	Up-regulation
AGC_RSK_RSKp90_RPS6KA3_ST	Q96RK0	CIC	P51812	RPS6KA3	S279	L286Q	286	Missense	distal	7	no	2.543	2.524	EPSD	COSMIC	1.803	Down-regulation
AGC_RSK_RSKp90_RPS6KA3_ST	Q96RK0	CIC	P51812	RPS6KA3	S279	D273E	273	Missense	distal	-6	no	2.543	2.553	EPSD	COSMIC	1.803	Up-regulation
AGC_RSK_RSKp90_RPS6KA3_ST	Q96RK0	CIC	P51812	RPS6KA3	S285	L286Q	286	Missense	proximal	1	no	1.803	1.774	EPSD	COSMIC	1.803	Loss
AGC_RSK_RSKp90_RPS6KA3_ST	Q96RK0	CIC	P51812	RPS6KA3	S285	H292R	292	Missense	distal	7	no	1.803	1.754	EPSD	COSMIC	1.803	Loss
AGC_RSK_RSKp90_RPS6KA3_ST	Q96RK0	CIC	P51812	RPS6KA3	S285	G287W	287	Missense	proximal	2	no	1.803	1.792	EPSD	COSMIC	1.803	Loss
AGC_RSK_RSKp90_RPS6KA3_ST	Q96RK0	CIC	P51812	RPS6KA3	S299	T303M	303	Missense	distal	4	no	3.678	3.650	EPSD	COSMIC	1.803	Down-regulation
AGC_RSK_RSKp90_RPS6KA3_ST	Q96RK0	CIC	P51812	RPS6KA3	S299	H292R	292	Missense	distal	-7	no	3.678	3.652	EPSD	COSMIC	1.803	Down-regulation
AGC_RSK_RSKp90_RPS6KA3_ST	Q96RK0	CIC	P51812	RPS6KA3	S299	M300I	300	Missense	proximal	1	no	3.678	3.691	EPSD	COSMIC	1.803	Up-regulation
AGC_RSK_RSKp90_RPS6KA3_ST	Q96RK0	CIC	P51812	RPS6KA3	S299	A306T	306	Missense	distal	7	no	3.678	3.707	EPSD	COSMIC	1.803	Up-regulation
AGC_RSK_RSKp90_RPS6KA3_ST	Q96RK0	CIC	P51812	RPS6KA3	S301	T303M	303	Missense	proximal	2	no	4.114	4.162	EPSD	COSMIC	1.803	Up-regulation
AGC_RSK_RSKp90_RPS6KA3_ST	Q96RK0	CIC	P51812	RPS6KA3	S301	M300I	300	Missense	proximal	-1	no	4.114	4.107	EPSD	COSMIC	1.803	Down-regulation
AGC_RSK_RSKp90_RPS6KA3_ST	Q96RK0	CIC	P51812	RPS6KA3	S301	A306T	306	Missense	distal	5	no	4.114	4.162	EPSD	COSMIC	1.803	Up-regulation
AGC_RSK_RSKp90_RPS6KA3_ST	Q96RK0	CIC	P51812	RPS6KA3	S334	P331S	331	Missense	distal	-3	no	2.036	2.143	EPSD	COSMIC	1.803	Up-regulation
AGC_RSK_RSKp90_RPS6KA3_ST	Q96RK0	CIC	P51812	RPS6KA3	S334	R340L	340	Missense	distal	6	no	2.036	1.965	EPSD	COSMIC;CCLE	1.803	Down-regulation
AGC_RSK_RSKp90_RPS6KA3_ST	Q96RK0	CIC	P51812	RPS6KA3	T343	R340L	340	Missense	distal	-3	no	2.613	0.382	EPSD	COSMIC;CCLE	1.803	Loss
AGC_RSK_RSKp90_RPS6KA3_ST	Q96RK0	CIC	P51812	RPS6KA3	T343	A350V	350	Missense	distal	7	no	2.613	2.645	EPSD	COSMIC	1.803	Up-regulation
AGC_RSK_RSKp90_RPS6KA3_ST	Q96RK0	CIC	P51812	RPS6KA3	S356	A354S	354	Missense	proximal	-2	no	4.102	4.140	EPSD	COSMIC	1.803	Up-regulation
AGC_RSK_RSKp90_RPS6KA3_ST	Q96RK0	CIC	P51812	RPS6KA3	S356	R351W	351	Missense	distal	-5	no	4.102	3.721	EPSD	COSMIC	1.803	Down-regulation
AGC_RSK_RSKp90_RPS6KA3_ST	Q96RK0	CIC	P51812	RPS6KA3	S356	G359E	359	Missense	distal	3	no	4.102	4.100	EPSD	COSMIC	1.803	Down-regulation
AGC_RSK_RSKp90_RPS6KA3_ST	Q96RK0	CIC	P51812	RPS6KA3	S356	R353Q	353	Missense	distal	-3	no	4.102	1.596	EPSD	COSMIC	1.803	Loss
AGC_RSK_RSKp90_RPS6KA3_ST	Q96RK0	CIC	P51812	RPS6KA3	S356	A350V	350	Missense	distal	-6	no	4.102	4.068	EPSD	COSMIC	1.803	Down-regulation
AGC_RSK_RSKp90_RPS6KA3_ST	Q96RK0	CIC	P51812	RPS6KA3	S356	G359R	359	Missense	distal	3	no	4.102	4.094	EPSD	COSMIC	1.803	Down-regulation
AGC_RSK_RSKp90_RPS6KA3_ST	Q96RK0	CIC	P51812	RPS6KA3	S362	G359R	359	Missense	distal	-3	no	1.124	3.506	EPSD	COSMIC	1.803	Gain
AGC_RSK_RSKp90_RPS6KA3_ST	Q96RK0	CIC	P51812	RPS6KA3	S496	S501Y	501	Missense	distal	5	no	1.897	1.972	EPSD	COSMIC	1.803	Up-regulation
AGC_RSK_RSKp90_RPS6KA3_ST	Q96RK0	CIC	P51812	RPS6KA3	S496	P497S	497	Missense	proximal	1	no	1.897	1.857	EPSD	COSMIC	1.803	Down-regulation
AGC_RSK_RSKp90_RPS6KA3_ST	Q96RK0	CIC	P51812	RPS6KA3	S496	R500H	500	Missense	distal	4	no	1.897	1.949	EPSD	COSMIC;GDSC;CCLE	1.803	Up-regulation
AGC_RSK_RSKp90_RPS6KA3_ST	Q96RK0	CIC	P51812	RPS6KA3	S502	R507H	507	Missense	distal	5	no	1.722	1.815	EPSD	COSMIC;GDSC	1.803	Gain
AGC_RSK_RSKp90_RPS6KA3_ST	Q96RK0	CIC	P51812	RPS6KA3	S538	S535F	535	Missense	distal	-3	no	1.807	0.954	EPSD	COSMIC	1.803	Loss
AGC_RSK_RSKp90_RPS6KA3_ST	Q96RK0	CIC	P51812	RPS6KA3	S538	A536V	536	Missense	proximal	-2	no	1.807	1.637	EPSD	COSMIC	1.803	Loss
AGC_RSK_RSKp90_RPS6KA3_ST	Q96RK0	CIC	P51812	RPS6KA3	S538	A531T	531	Missense	distal	-7	no	1.807	1.823	EPSD	COSMIC	1.803	Up-regulation
AGC_RSK_RSKp90_RPS6KA3_ST	Q96RK0	CIC	P51812	RPS6KA3	S538	P532L	532	Missense	distal	-6	no	1.807	1.790	EPSD	COSMIC	1.803	Loss
AGC_RSK_RSKp90_RPS6KA3_ST	Q96RK0	CIC	P51812	RPS6KA3	S538	S538L	538	Missense	central	0	yes	1.807	0.000	EPSD	COSMIC	1.803	Loss
AGC_RSK_RSKp90_RPS6KA3_ST	Q96RK0	CIC	P51812	RPS6KA3	S538	A544P	544	Missense	distal	6	no	1.807	1.800	EPSD	COSMIC	1.803	Loss
AGC_RSK_RSKp90_RPS6KA3_ST	Q96RK0	CIC	P51812	RPS6KA3	S541	S535F	535	Missense	distal	-6	no	1.907	1.851	EPSD	COSMIC	1.803	Down-regulation
AGC_RSK_RSKp90_RPS6KA3_ST	Q96RK0	CIC	P51812	RPS6KA3	S541	A536V	536	Missense	distal	-5	no	1.907	1.790	EPSD	COSMIC	1.803	Loss
AGC_RSK_RSKp90_RPS6KA3_ST	Q96RK0	CIC	P51812	RPS6KA3	S541	A546T	546	Missense	distal	5	no	1.907	1.954	EPSD	COSMIC	1.803	Up-regulation
AGC_RSK_RSKp90_RPS6KA3_ST	Q96RK0	CIC	P51812	RPS6KA3	S541	S538L	538	Missense	distal	-3	no	1.907	1.683	EPSD	COSMIC	1.803	Loss
AGC_RSK_RSKp90_RPS6KA3_ST	Q96RK0	CIC	P51812	RPS6KA3	S541	A544P	544	Missense	distal	3	no	1.907	1.908	EPSD	COSMIC	1.803	Up-regulation
AGC_RSK_RSKp90_RPS6KA3_ST	Q96RK0	CIC	P51812	RPS6KA3	S543	A536V	536	Missense	distal	-7	no	2.204	2.219	EPSD	COSMIC	1.803	Up-regulation
AGC_RSK_RSKp90_RPS6KA3_ST	Q96RK0	CIC	P51812	RPS6KA3	S543	A546T	546	Missense	distal	3	no	2.204	2.209	EPSD	COSMIC	1.803	Up-regulation
AGC_RSK_RSKp90_RPS6KA3_ST	Q96RK0	CIC	P51812	RPS6KA3	S543	S538L	538	Missense	distal	-5	no	2.204	2.175	EPSD	COSMIC	1.803	Down-regulation
AGC_RSK_RSKp90_RPS6KA3_ST	Q96RK0	CIC	P51812	RPS6KA3	S543	A544P	544	Missense	proximal	1	no	2.204	2.223	EPSD	COSMIC	1.803	Up-regulation
AGC_RSK_RSKp90_RPS6KA3_ST	Q96RK0	CIC	P51812	RPS6KA3	S562	Q560R	560	Missense	proximal	-2	no	1.378	1.903	EPSD	COSMIC	1.803	Gain
AGC_RSK_RSKp90_RPS6KA3_ST	Q96RK0	CIC	P51812	RPS6KA3	S605	R600C	600	Missense	distal	-5	no	3.884	3.483	EPSD	COSMIC;CCLE	1.803	Down-regulation
AGC_RSK_RSKp90_RPS6KA3_ST	Q96RK0	CIC	P51812	RPS6KA3	S605	E604K	604	Missense	proximal	-1	no	3.884	3.901	EPSD	COSMIC	1.803	Up-regulation
AGC_RSK_RSKp90_RPS6KA3_ST	Q96RK0	CIC	P51812	RPS6KA3	S605	F598L	598	Missense	distal	-7	no	3.884	3.878	EPSD	COSMIC	1.803	Down-regulation
AGC_RSK_RSKp90_RPS6KA3_ST	Q96RK0	CIC	P51812	RPS6KA3	S605	P603L	603	Missense	proximal	-2	no	3.884	3.847	EPSD	COSMIC	1.803	Down-regulation
AGC_RSK_RSKp90_RPS6KA3_ST	Q96RK0	CIC	P51812	RPS6KA3	S605	P611S	611	Missense	distal	6	no	3.884	3.919	EPSD	COSMIC	1.803	Up-regulation
AGC_RSK_RSKp90_RPS6KA3_ST	Q96RK0	CIC	P51812	RPS6KA3	S605	R599W	599	Missense	distal	-6	no	3.884	3.804	EPSD	COSMIC	1.803	Down-regulation
AGC_RSK_RSKp90_RPS6KA3_ST	Q96RK0	CIC	P51812	RPS6KA3	S649	A656V	656	Missense	distal	7	no	3.204	3.235	EPSD	COSMIC	1.803	Up-regulation
AGC_RSK_RSKp90_RPS6KA3_ST	Q96RK0	CIC	P51812	RPS6KA3	S649	A645T	645	Missense	distal	-4	no	3.204	3.124	EPSD	COSMIC	1.803	Down-regulation
AGC_RSK_RSKp90_RPS6KA3_ST	Q96RK0	CIC	P51812	RPS6KA3	S649	R646T	646	Missense	distal	-3	no	3.204	0.765	EPSD	COSMIC	1.803	Loss
AGC_RSK_RSKp90_RPS6KA3_ST	Q96RK0	CIC	P51812	RPS6KA3	S721	G720V	720	Missense	proximal	-1	no	1.823	1.809	EPSD	COSMIC	1.803	Down-regulation
AGC_RSK_RSKp90_RPS6KA3_ST	Q96RK0	CIC	P51812	RPS6KA3	S721	G714V	714	Missense	distal	-7	no	1.823	1.827	EPSD	COSMIC	1.803	Up-regulation
AGC_RSK_RSKp90_RPS6KA3_ST	Q96RK0	CIC	P51812	RPS6KA3	S721	R716W	716	Missense	distal	-5	no	1.823	1.442	EPSD	COSMIC	1.803	Loss
AGC_RSK_RSKp90_RPS6KA3_ST	Q96RK0	CIC	P51812	RPS6KA3	S721	S726R	726	Missense	distal	5	no	1.823	1.792	EPSD	COSMIC	1.803	Loss
AGC_RSK_RSKp90_RPS6KA3_ST	Q96RK0	CIC	P51812	RPS6KA3	S721	S721F	721	Missense	central	0	yes	1.823	0.000	EPSD	COSMIC	1.803	Loss
AGC_RSK_RSKp90_RPS6KA3_ST	Q96RK0	CIC	P51812	RPS6KA3	S721	S721C	721	Missense	central	0	yes	1.823	0.000	EPSD	COSMIC	1.803	Loss
AGC_RSK_RSKp90_RPS6KA3_ST	Q96RK0	CIC	P51812	RPS6KA3	S739	P742S	742	Missense	distal	3	no	1.976	1.971	EPSD	COSMIC	1.803	Down-regulation
AGC_RSK_RSKp90_RPS6KA3_ST	Q96RK0	CIC	P51812	RPS6KA3	S739	K732Q	732	Missense	distal	-7	no	1.976	1.981	EPSD	COSMIC	1.803	Up-regulation
AGC_RSK_RSKp90_RPS6KA3_ST	Q96RK0	CIC	P51812	RPS6KA3	S902	A900V	900	Missense	proximal	-2	no	1.899	1.728	EPSD	COSMIC	1.803	Loss
AGC_RSK_RSKp90_RPS6KA3_ST	Q96RK0	CIC	P51812	RPS6KA3	S902	P896L	896	Missense	distal	-6	no	1.899	1.881	EPSD	COSMIC	1.803	Down-regulation
AGC_RSK_RSKp90_RPS6KA3_ST	Q96RK0	CIC	P51812	RPS6KA3	S902	P897R	897	Missense	distal	-5	no	1.899	2.223	EPSD	COSMIC	1.803	Up-regulation
AGC_RSK_RSKp90_RPS6KA3_ST	Q96RK0	CIC	P51812	RPS6KA3	S982	P987S	987	Missense	distal	5	no	1.945	1.905	EPSD	COSMIC	1.803	Down-regulation
AGC_RSK_RSKp90_RPS6KA3_ST	Q96RK0	CIC	P51812	RPS6KA3	S982	P983S	983	Missense	proximal	1	no	1.945	1.906	EPSD	COSMIC	1.803	Down-regulation
AGC_RSK_RSKp90_RPS6KA3_ST	Q96RK0	CIC	P51812	RPS6KA3	S982	L986V	986	Missense	distal	4	no	1.945	1.943	EPSD	COSMIC;GDSC	1.803	Down-regulation
AGC_RSK_RSKp90_RPS6KA3_ST	Q96RK0	CIC	P51812	RPS6KA3	S982	P980L	980	Missense	proximal	-2	no	1.945	1.908	EPSD	COSMIC	1.803	Down-regulation
AGC_RSK_RSKp90_RPS6KA3_ST	Q96RK0	CIC	P51812	RPS6KA3	T1217	A1218V	1218	Missense	proximal	1	no	1.921	1.969	EPSD	COSMIC	1.803	Up-regulation
AGC_RSK_RSKp90_RPS6KA3_ST	Q96RK0	CIC	P51812	RPS6KA3	T1217	E1215D	1215	Missense	proximal	-2	no	1.921	1.878	EPSD	COSMIC	1.803	Down-regulation
AGC_RSK_RSKp90_RPS6KA3_ST	Q96RK0	CIC	P51812	RPS6KA3	T1217	P1210T	1210	Missense	distal	-7	no	1.921	1.931	EPSD	COSMIC	1.803	Up-regulation
AGC_RSK_RSKp90_RPS6KA3_ST	Q96RK0	CIC	P51812	RPS6KA3	T1217	R1214Q	1214	Missense	distal	-3	no	1.921	-0.586	EPSD	COSMIC	1.803	Loss
AGC_RSK_RSKp90_RPS6KA3_ST	Q96RK0	CIC	P51812	RPS6KA3	T1217	E1222Q	1222	Missense	distal	5	no	1.921	1.912	EPSD	COSMIC	1.803	Down-regulation
AGC_RSK_RSKp90_RPS6KA3_ST	Q96RK0	CIC	P51812	RPS6KA3	T1217	E1222G	1222	Missense	distal	5	no	1.921	1.947	EPSD	COSMIC	1.803	Up-regulation
AGC_RSK_RSKp90_RPS6KA3_ST	Q96RK0	CIC	P51812	RPS6KA3	S1245	T1242R	1242	Missense	distal	-3	no	1.179	3.618	EPSD	COSMIC	1.803	Gain
AGC_RSK_RSKp90_RPS6KA3_ST	Q96RK0	CIC	P51812	RPS6KA3	S1246	P1248L	1248	Missense	proximal	2	no	1.922	1.886	EPSD	COSMIC	1.803	Down-regulation
AGC_RSK_RSKp90_RPS6KA3_ST	Q96RK0	CIC	P51812	RPS6KA3	S1246	W1239R	1239	Missense	distal	-7	no	1.922	1.896	EPSD	COSMIC	1.803	Down-regulation
AGC_RSK_RSKp90_RPS6KA3_ST	Q96RK0	CIC	P51812	RPS6KA3	S1246	P1248S	1248	Missense	proximal	2	no	1.922	1.993	EPSD	COSMIC	1.803	Up-regulation
AGC_RSK_RSKp90_RPS6KA3_ST	Q96RK0	CIC	P51812	RPS6KA3	S1246	T1242R	1242	Missense	distal	-4	no	1.922	2.137	EPSD	COSMIC	1.803	Up-regulation
AGC_RSK_RSKp90_RPS6KA3_ST	Q96RK0	CIC	P51812	RPS6KA3	S1246	T1240R	1240	Missense	distal	-6	no	1.922	2.004	EPSD	COSMIC	1.803	Up-regulation
AGC_RSK_RSKp90_RPS6KA3_ST	Q96RK0	CIC	P51812	RPS6KA3	S1310	G1316R	1316	Missense	distal	6	no	1.756	1.819	EPSD	COSMIC	1.803	Gain
AGC_RSK_RSKp90_RPS6KA3_ST	Q96RK0	CIC	P51812	RPS6KA3	S1351	S1344F	1344	Missense	distal	-7	no	3.301	3.326	EPSD	COSMIC	1.803	Up-regulation
AGC_RSK_RSKp90_RPS6KA3_ST	Q96RK0	CIC	P51812	RPS6KA3	S1351	R1348K	1348	Missense	distal	-3	no	3.301	1.334	EPSD	COSMIC	1.803	Loss
AGC_RSK_RSKp90_RPS6KA3_ST	Q96RK0	CIC	P51812	RPS6KA3	S1397	D1401E	1401	Missense	distal	4	no	4.077	4.060	EPSD	COSMIC	1.803	Down-regulation
AGC_RSK_RSKp90_RPS6KA3_ST	Q96RK0	CIC	P51812	RPS6KA3	S1397	D1401H	1401	Missense	distal	4	no	4.077	4.073	EPSD	COSMIC	1.803	Down-regulation
AGC_RSK_RSKp90_RPS6KA3_ST	Q96RK0	CIC	P51812	RPS6KA3	S1397	D1399H	1399	Missense	proximal	2	no	4.077	4.086	EPSD	COSMIC	1.803	Up-regulation
AGC_RSK_RSKp90_RPS6KA3_ST	Q96RK0	CIC	P51812	RPS6KA3	S1418	S1418C	1418	Missense	central	0	yes	4.322	0.000	EPSD	COSMIC	1.803	Loss
AGC_RSK_RSKp90_RPS6KA3_ST	Q96RK0	CIC	P51812	RPS6KA3	S1418	R1412H	1412	Missense	distal	-6	no	4.322	4.242	EPSD	COSMIC	1.803	Down-regulation
AGC_RSK_RSKp90_RPS6KA3_ST	Q96RK0	CIC	P51812	RPS6KA3	S1418	R1417L	1417	Missense	proximal	-1	no	4.322	4.251	EPSD	COSMIC	1.803	Down-regulation
AGC_RSK_RSKp90_RPS6KA3_ST	Q96RK0	CIC	P51812	RPS6KA3	S1418	S1421G	1421	Missense	distal	3	no	4.322	4.329	EPSD	COSMIC	1.803	Up-regulation
AGC_RSK_RSKp90_RPS6KA3_ST	Q96RK0	CIC	P51812	RPS6KA3	S1418	R1416H	1416	Missense	proximal	-2	no	4.322	3.766	EPSD	COSMIC;CCLE	1.803	Down-regulation
AGC_RSK_RSKp90_RPS6KA3_ST	Q96RK0	CIC	P51812	RPS6KA3	S1418	P1424S	1424	Missense	distal	6	no	4.322	4.356	EPSD	COSMIC	1.803	Up-regulation
AGC_RSK_RSKp90_RPS6KA3_ST	Q96RK0	CIC	P51812	RPS6KA3	S1418	S1419G	1419	Missense	proximal	1	no	4.322	4.380	EPSD	COSMIC	1.803	Up-regulation
AGC_RSK_RSKp90_RPS6KA3_ST	Q96RK0	CIC	P51812	RPS6KA3	S1418	R1415L	1415	Missense	distal	-3	no	4.322	2.091	EPSD	COSMIC	1.803	Down-regulation
AGC_RSK_RSKp90_RPS6KA3_ST	Q96RK0	CIC	P51812	RPS6KA3	S1418	S1422W	1422	Missense	distal	4	no	4.322	4.377	EPSD	COSMIC	1.803	Up-regulation
AGC_RSK_RSKp90_RPS6KA3_ST	Q96RK0	CIC	P51812	RPS6KA3	S1419	S1418C	1418	Missense	proximal	-1	no	4.181	4.137	EPSD	COSMIC	1.803	Down-regulation
AGC_RSK_RSKp90_RPS6KA3_ST	Q96RK0	CIC	P51812	RPS6KA3	S1419	R1412H	1412	Missense	distal	-7	no	4.181	4.207	EPSD	COSMIC	1.803	Up-regulation
AGC_RSK_RSKp90_RPS6KA3_ST	Q96RK0	CIC	P51812	RPS6KA3	S1419	R1417L	1417	Missense	proximal	-2	no	4.181	3.674	EPSD	COSMIC	1.803	Down-regulation
AGC_RSK_RSKp90_RPS6KA3_ST	Q96RK0	CIC	P51812	RPS6KA3	S1419	S1421G	1421	Missense	proximal	2	no	4.181	4.096	EPSD	COSMIC	1.803	Down-regulation
AGC_RSK_RSKp90_RPS6KA3_ST	Q96RK0	CIC	P51812	RPS6KA3	S1419	R1416H	1416	Missense	distal	-3	no	4.181	1.643	EPSD	COSMIC;CCLE	1.803	Loss
AGC_RSK_RSKp90_RPS6KA3_ST	Q96RK0	CIC	P51812	RPS6KA3	S1419	P1424S	1424	Missense	distal	5	no	4.181	4.141	EPSD	COSMIC	1.803	Down-regulation
AGC_RSK_RSKp90_RPS6KA3_ST	Q96RK0	CIC	P51812	RPS6KA3	S1419	S1419G	1419	Missense	central	0	yes	4.181	0.000	EPSD	COSMIC	1.803	Loss
AGC_RSK_RSKp90_RPS6KA3_ST	Q96RK0	CIC	P51812	RPS6KA3	S1419	R1415L	1415	Missense	distal	-4	no	4.181	3.992	EPSD	COSMIC	1.803	Down-regulation
AGC_RSK_RSKp90_RPS6KA3_ST	Q96RK0	CIC	P51812	RPS6KA3	S1419	S1422W	1422	Missense	distal	3	no	4.181	4.188	EPSD	COSMIC	1.803	Up-regulation
AGC_RSK_RSKp90_RPS6KA3_ST	Q96RK0	CIC	P51812	RPS6KA3	S1421	S1418C	1418	Missense	distal	-3	no	2.094	1.491	EPSD	COSMIC	1.803	Loss
AGC_RSK_RSKp90_RPS6KA3_ST	Q96RK0	CIC	P51812	RPS6KA3	S1421	R1417L	1417	Missense	distal	-4	no	2.094	1.906	EPSD	COSMIC	1.803	Down-regulation
AGC_RSK_RSKp90_RPS6KA3_ST	Q96RK0	CIC	P51812	RPS6KA3	S1421	S1421G	1421	Missense	central	0	yes	2.094	0.000	EPSD	COSMIC	1.803	Loss
AGC_RSK_RSKp90_RPS6KA3_ST	Q96RK0	CIC	P51812	RPS6KA3	S1421	R1416H	1416	Missense	distal	-5	no	2.094	1.711	EPSD	COSMIC;CCLE	1.803	Loss
AGC_RSK_RSKp90_RPS6KA3_ST	Q96RK0	CIC	P51812	RPS6KA3	S1421	P1427L	1427	Missense	distal	6	no	2.094	2.076	EPSD	COSMIC	1.803	Down-regulation
AGC_RSK_RSKp90_RPS6KA3_ST	Q96RK0	CIC	P51812	RPS6KA3	S1421	P1424S	1424	Missense	distal	3	no	2.094	2.089	EPSD	COSMIC	1.803	Down-regulation
AGC_RSK_RSKp90_RPS6KA3_ST	Q96RK0	CIC	P51812	RPS6KA3	S1421	S1419G	1419	Missense	proximal	-2	no	2.094	1.976	EPSD	COSMIC	1.803	Down-regulation
AGC_RSK_RSKp90_RPS6KA3_ST	Q96RK0	CIC	P51812	RPS6KA3	S1421	R1415L	1415	Missense	distal	-6	no	2.094	2.012	EPSD	COSMIC	1.803	Down-regulation
AGC_RSK_RSKp90_RPS6KA3_ST	Q96RK0	CIC	P51812	RPS6KA3	S1421	S1422W	1422	Missense	proximal	1	no	2.094	2.143	EPSD	COSMIC	1.803	Up-regulation
AGC_RSK_RSKp90_RPS6KA3_ST	Q96RK0	CIC	P51812	RPS6KA3	S1422	S1418C	1418	Missense	distal	-4	no	1.966	1.862	EPSD	COSMIC	1.803	Down-regulation
AGC_RSK_RSKp90_RPS6KA3_ST	Q96RK0	CIC	P51812	RPS6KA3	S1422	R1417L	1417	Missense	distal	-5	no	1.966	1.620	EPSD	COSMIC	1.803	Loss
AGC_RSK_RSKp90_RPS6KA3_ST	Q96RK0	CIC	P51812	RPS6KA3	S1422	S1421G	1421	Missense	proximal	-1	no	1.966	1.929	EPSD	COSMIC	1.803	Down-regulation
AGC_RSK_RSKp90_RPS6KA3_ST	Q96RK0	CIC	P51812	RPS6KA3	S1422	R1416H	1416	Missense	distal	-6	no	1.966	1.886	EPSD	COSMIC;CCLE	1.803	Down-regulation
AGC_RSK_RSKp90_RPS6KA3_ST	Q96RK0	CIC	P51812	RPS6KA3	S1422	P1427L	1427	Missense	distal	5	no	1.966	2.004	EPSD	COSMIC	1.803	Up-regulation
AGC_RSK_RSKp90_RPS6KA3_ST	Q96RK0	CIC	P51812	RPS6KA3	S1422	P1424S	1424	Missense	proximal	2	no	1.966	2.037	EPSD	COSMIC	1.803	Up-regulation
AGC_RSK_RSKp90_RPS6KA3_ST	Q96RK0	CIC	P51812	RPS6KA3	S1422	S1419G	1419	Missense	distal	-3	no	1.966	1.591	EPSD	COSMIC	1.803	Loss
AGC_RSK_RSKp90_RPS6KA3_ST	Q96RK0	CIC	P51812	RPS6KA3	S1422	R1415L	1415	Missense	distal	-7	no	1.966	1.995	EPSD	COSMIC	1.803	Up-regulation
AGC_RSK_RSKp90_RPS6KA3_ST	Q96RK0	CIC	P51812	RPS6KA3	S1422	S1422W	1422	Missense	central	0	yes	1.966	0.000	EPSD	COSMIC	1.803	Loss
AGC_RSK_RSKp90_RPS6KA3_ST	P25963	NFKBIA	P51812	RPS6KA3	S32	M37K	37	Missense	distal	5	no	3.469	3.440	PhosphoSitePlus	COSMIC	1.803	Down-regulation
AGC_RSK_RSKp90_RPS6KA3_ST	P25963	NFKBIA	P51812	RPS6KA3	S32	S36P	36	Missense	distal	4	no	3.469	3.508	PhosphoSitePlus	COSMIC	1.803	Up-regulation
AGC_RSK_RSKp90_RPS6KA3_ST	P25963	NFKBIA	P51812	RPS6KA3	S32	S32N	32	Missense	central	0	yes	3.469	0.000	PhosphoSitePlus	COSMIC	1.803	Loss
AGC_RSK_RSKp90_RPS6KA3_ST	P05198	EIF2S1	P51812	RPS6KA3	S58	R55H	55	Missense	distal	-3	no	4.028	1.490	EPSD	COSMIC	1.803	Loss
AGC_RSK_RSKp90_RPS6KA3_ST	P05198	EIF2S1	P51812	RPS6KA3	S58	R55C	55	Missense	distal	-3	no	4.028	1.418	EPSD	COSMIC	1.803	Loss
AGC_RSK_RSKp90_RPS6KA3_ST	P49840	GSK3A	P51812	RPS6KA3	S97	V104I	104	Missense	distal	7	no	1.974	1.964	EPSD	COSMIC;GDSC;CCLE	1.803	Down-regulation
AGC_RSK_RSKp90_RPS6KA3_ST	O14649	KCNK3	P51812	RPS6KA3	S392	R385H	385	Missense	distal	-7	no	2.012	2.038	EPSD	COSMIC	1.803	Up-regulation
CK1_TTBK_TTBK2_ST	Q7L0J3	SV2A	Q6IQ55	TTBK2	S42	R48H	48	Missense	distal	6	no	7.526	7.554	EPSD;PhosphoSitePlus	COSMIC	3.341	Up-regulation
CK1_TTBK_TTBK2_ST	Q7L0J3	SV2A	Q6IQ55	TTBK2	S42	F49I	49	Missense	distal	7	no	7.526	7.547	EPSD;PhosphoSitePlus	COSMIC	3.341	Up-regulation
CK1_TTBK_TTBK2_ST	Q7L0J3	SV2A	Q6IQ55	TTBK2	S42	R36K	36	Missense	distal	-6	no	7.526	7.403	EPSD;PhosphoSitePlus	COSMIC	3.341	Down-regulation
CK1_TTBK_TTBK2_ST	Q7L0J3	SV2A	Q6IQ55	TTBK2	S42	V37A	37	Missense	distal	-5	no	7.526	7.817	EPSD;PhosphoSitePlus	COSMIC;GDSC;CCLE	3.341	Up-regulation
CK1_TTBK_TTBK2_ST	Q7L0J3	SV2A	Q6IQ55	TTBK2	S45	R48H	48	Missense	distal	3	no	7.586	7.578	EPSD;PhosphoSitePlus	COSMIC	3.341	Down-regulation
CK1_TTBK_TTBK2_ST	Q7L0J3	SV2A	Q6IQ55	TTBK2	S45	F49I	49	Missense	distal	4	no	7.586	7.693	EPSD;PhosphoSitePlus	COSMIC	3.341	Up-regulation
CK1_TTBK_TTBK2_ST	Q7L0J3	SV2A	Q6IQ55	TTBK2	S47	R48H	48	Missense	proximal	1	no	7.658	7.624	PhosphoSitePlus;EPSD	COSMIC	3.341	Down-regulation
CK1_TTBK_TTBK2_ST	Q7L0J3	SV2A	Q6IQ55	TTBK2	S47	F49I	49	Missense	proximal	2	no	7.658	7.621	PhosphoSitePlus;EPSD	COSMIC	3.341	Down-regulation
CK1_TTBK_TTBK2_ST	Q7L0J3	SV2A	Q6IQ55	TTBK2	S80	H87L	87	Missense	distal	7	no	6.833	6.866	EPSD;PhosphoSitePlus	COSMIC	3.341	Up-regulation
CK1_TTBK_TTBK2_ST	Q7L0J3	SV2A	Q6IQ55	TTBK2	S80	D73N	73	Missense	distal	-7	no	6.833	6.469	EPSD;PhosphoSitePlus	COSMIC	3.341	Down-regulation
CK1_TTBK_TTBK2_ST	Q7L0J3	SV2A	Q6IQ55	TTBK2	S81	D88H	88	Missense	distal	7	no	7.524	7.567	EPSD;PhosphoSitePlus	COSMIC	3.341	Up-regulation
CK1_TTBK_TTBK2_ST	Q7L0J3	SV2A	Q6IQ55	TTBK2	S81	D88E	88	Missense	distal	7	no	7.524	7.505	EPSD;PhosphoSitePlus	COSMIC	3.341	Down-regulation
CK1_TTBK_TTBK2_ST	Q7L0J3	SV2A	Q6IQ55	TTBK2	S81	D88A	88	Missense	distal	7	no	7.524	7.565	EPSD;PhosphoSitePlus	COSMIC	3.341	Up-regulation
CK1_TTBK_TTBK2_ST	Q7L0J3	SV2A	Q6IQ55	TTBK2	S81	H87L	87	Missense	distal	6	no	7.524	7.400	EPSD;PhosphoSitePlus	COSMIC	3.341	Down-regulation
CK1_TTBK_TTBK2_ST	Q7L0J3	SV2A	Q6IQ55	TTBK2	T84	D88H	88	Missense	distal	4	no	6.838	7.019	EPSD;PhosphoSitePlus	COSMIC	3.341	Up-regulation
CK1_TTBK_TTBK2_ST	Q7L0J3	SV2A	Q6IQ55	TTBK2	T84	D88E	88	Missense	distal	4	no	6.838	6.774	EPSD;PhosphoSitePlus	COSMIC	3.341	Down-regulation
CK1_TTBK_TTBK2_ST	Q7L0J3	SV2A	Q6IQ55	TTBK2	T84	D88A	88	Missense	distal	4	no	6.838	6.989	EPSD;PhosphoSitePlus	COSMIC	3.341	Up-regulation
CK1_TTBK_TTBK2_ST	Q7L0J3	SV2A	Q6IQ55	TTBK2	T84	H87L	87	Missense	distal	3	no	6.838	6.851	EPSD;PhosphoSitePlus	COSMIC	3.341	Up-regulation
CK1_TTBK_TTBK2_ST	Q7L0J3	SV2A	Q6IQ55	TTBK2	T84	E89K	89	Missense	distal	5	no	6.838	4.849	EPSD;PhosphoSitePlus	COSMIC	3.341	Down-regulation
CK1_TTBK_TTBK2_ST	Q7L0J3	SV2A	Q6IQ55	TTBK2	S482	R483H	483	Missense	proximal	1	no	3.525	3.491	EPSD	COSMIC	3.341	Down-regulation
CK1_TTBK_TTBK2_ST	Q7L0J3	SV2A	Q6IQ55	TTBK2	S482	A481T	481	Missense	proximal	-1	no	3.525	3.527	EPSD	COSMIC;CCLE	3.341	Up-regulation
CK1_TTBK_TTBK2_ST	Q7L0J3	SV2A	Q6IQ55	TTBK2	S482	G489R	489	Missense	distal	7	no	3.525	3.520	EPSD	COSMIC	3.341	Down-regulation
CK1_TTBK_TTBK2_ST	Q7L0J3	SV2A	Q6IQ55	TTBK2	S482	V486E	486	Missense	distal	4	no	3.525	3.172	EPSD	COSMIC	3.341	Loss
CK1_TTBK_TTBK2_ST	Q7L0J3	SV2A	Q6IQ55	TTBK2	S482	R483L	483	Missense	proximal	1	no	3.525	3.546	EPSD	COSMIC	3.341	Up-regulation
CK1_TTBK_TTBK2_ST	O00139	KIF2A	Q6IQ55	TTBK2	S121	S128Y	128	Missense	distal	7	no	3.670	3.700	EPSD	COSMIC	3.341	Up-regulation
CK1_TTBK_TTBK2_ST	O00139	KIF2A	Q6IQ55	TTBK2	S121	R119Q	119	Missense	proximal	-2	no	3.670	3.658	EPSD	COSMIC	3.341	Down-regulation
CK1_TTBK_TTBK2_ST	O00139	KIF2A	Q6IQ55	TTBK2	S135	V142I	142	Missense	distal	7	no	6.777	6.741	PhosphoSitePlus	COSMIC	3.341	Down-regulation
CK1_TTBK_TTBK2_ST	O00139	KIF2A	Q6IQ55	TTBK2	S135	S128Y	128	Missense	distal	-7	no	6.777	6.306	PhosphoSitePlus	COSMIC	3.341	Down-regulation
CK1_TTBK_TTBK2_ST	O00139	KIF2A	Q6IQ55	TTBK2	S135	P141L	141	Missense	distal	6	no	6.777	6.684	PhosphoSitePlus	COSMIC	3.341	Down-regulation
CK1_TTBK_TTBK2_ST	O00139	KIF2A	Q6IQ55	TTBK2	S157	E162A	162	Missense	distal	5	no	4.143	2.449	EPSD	COSMIC	3.341	Loss
CK1_TTBK_TTBK2_ST	O00139	KIF2A	Q6IQ55	TTBK2	S250	M255I	255	Missense	distal	5	no	3.357	3.141	EPSD	COSMIC	3.341	Loss
CK1_TTBK_TTBK2_ST	O00139	KIF2A	Q6IQ55	TTBK2	S250	D252H	252	Missense	proximal	2	no	3.357	3.446	EPSD	COSMIC	3.341	Up-regulation
CK1_TTBK_TTBK2_ST	O00139	KIF2A	Q6IQ55	TTBK2	S604	S604F	604	Missense	central	0	yes	3.853	0.000	EPSD	COSMIC	3.341	Loss
CK1_TTBK_TTBK2_ST	O00139	KIF2A	Q6IQ55	TTBK2	S604	V603I	603	Missense	proximal	-1	no	3.853	3.850	EPSD	COSMIC	3.341	Down-regulation
CK1_TTBK_TTBK2_ST	O00139	KIF2A	Q6IQ55	TTBK2	S604	Q598H	598	Missense	distal	-6	no	3.853	3.903	EPSD	COSMIC	3.341	Up-regulation
CK1_TTBK_TTBK2_ST	O00139	KIF2A	Q6IQ55	TTBK2	S615	E612K	612	Missense	distal	-3	no	3.490	3.528	EPSD	COSMIC	3.341	Up-regulation
CK1_TTBK_TTBK2_ST	O00139	KIF2A	Q6IQ55	TTBK2	S635	R637Q	637	Missense	proximal	2	no	3.672	3.634	EPSD	COSMIC	3.341	Down-regulation
CK1_TTBK_TTBK2_ST	O00139	KIF2A	Q6IQ55	TTBK2	S635	H628Y	628	Missense	distal	-7	no	3.672	3.527	EPSD	COSMIC	3.341	Down-regulation
CK1_TTBK_TTBK2_ST	O00139	KIF2A	Q6IQ55	TTBK2	S635	I636V	636	Missense	proximal	1	no	3.672	3.739	EPSD	COSMIC	3.341	Up-regulation
CK1_TTBK_TTBK2_ST	O00139	KIF2A	Q6IQ55	TTBK2	S635	E640K	640	Missense	distal	5	no	3.672	1.683	EPSD	COSMIC	3.341	Loss
CK1_TTBK_TTBK2_ST	O00139	KIF2A	Q6IQ55	TTBK2	S683	K680T	680	Missense	distal	-3	no	3.698	3.706	EPSD	COSMIC	3.341	Up-regulation
CK1_TTBK_TTBK2_ST	O00139	KIF2A	Q6IQ55	TTBK2	S683	S683C	683	Missense	central	0	yes	3.698	0.000	EPSD	COSMIC	3.341	Loss
CK1_TTBK_TTBK2_ST	O00139	KIF2A	Q6IQ55	TTBK2	S683	R678Q	678	Missense	distal	-5	no	3.698	3.936	EPSD	COSMIC	3.341	Up-regulation
CK1_TTBK_TTBK2_ST	O00139	KIF2A	Q6IQ55	TTBK2	S683	R678W	678	Missense	distal	-5	no	3.698	3.831	EPSD	COSMIC;CCLE	3.341	Up-regulation
CK1_TTBK_TTBK2_ST	O00139	KIF2A	Q6IQ55	TTBK2	S683	V681E	681	Missense	proximal	-2	no	3.698	3.623	EPSD	COSMIC	3.341	Down-regulation
CK1_TTBK_TTBK2_ST	O00139	KIF2A	Q6IQ55	TTBK2	S683	S683Y	683	Missense	central	0	yes	3.698	0.000	EPSD	COSMIC	3.341	Loss
TK_Tec_BTK_Y	P78347	GTF2I	Q06187	BTK	Y248	E242K	242	Missense	distal	-6	no	3.535	3.529	PhosphoSitePlus;EPSD	COSMIC	1.787	Down-regulation
TK_Tec_BTK_Y	P78347	GTF2I	Q06187	BTK	Y398	H393Y	393	Missense	distal	-5	no	3.382	3.119	EPSD	COSMIC	1.787	Down-regulation
TK_Tec_BTK_Y	P78347	GTF2I	Q06187	BTK	Y398	Q391P	391	Missense	distal	-7	no	3.382	3.223	EPSD	COSMIC	1.787	Down-regulation
TK_Tec_BTK_Y	P78347	GTF2I	Q06187	BTK	Y398	L397F	397	Missense	proximal	-1	no	3.382	2.141	EPSD	COSMIC	1.787	Down-regulation
TK_Tec_BTK_Y	P16885	PLCG2	Q06187	BTK	Y495	H494L	494	Missense	proximal	-1	no	1.017	2.222	EPSD	COSMIC	1.787	Gain
TK_Tec_BTK_Y	P16885	PLCG2	Q06187	BTK	Y753	M758I	758	Missense	distal	5	no	3.510	3.637	PhosphoSitePlus;EPSD	COSMIC	1.787	Up-regulation
TK_Tec_BTK_Y	P16885	PLCG2	Q06187	BTK	Y753	S751F	751	Missense	proximal	-2	no	3.510	3.640	PhosphoSitePlus;EPSD	COSMIC	1.787	Up-regulation
TK_Tec_BTK_Y	P16885	PLCG2	Q06187	BTK	Y759	P762L	762	Missense	distal	3	no	3.275	3.345	EPSD;PhosphoSitePlus	COSMIC	1.787	Up-regulation
TK_Tec_BTK_Y	P16885	PLCG2	Q06187	BTK	Y759	M758I	758	Missense	proximal	-1	no	3.275	4.120	EPSD;PhosphoSitePlus	COSMIC	1.787	Up-regulation
TK_Tec_BTK_Y	P16885	PLCG2	Q06187	BTK	Y1197	E1191D	1191	Missense	distal	-6	no	3.522	3.509	EPSD	COSMIC	1.787	Down-regulation
TK_Tec_BTK_Y	P16885	PLCG2	Q06187	BTK	Y1197	L1203P	1203	Missense	distal	6	no	3.522	3.280	EPSD	COSMIC	1.787	Down-regulation
TK_Tec_BTK_Y	P16885	PLCG2	Q06187	BTK	Y1217	L1223V	1223	Missense	distal	6	no	3.342	3.134	EPSD	COSMIC	1.787	Down-regulation
TK_Tec_BTK_Y	P58753	TIRAP	Q06187	BTK	Y86	V90M	90	Missense	distal	4	no	3.268	3.289	EPSD;PhosphoSitePlus	COSMIC	1.787	Up-regulation
TK_Tec_BTK_Y	P58753	TIRAP	Q06187	BTK	Y86	D87Y	87	Missense	proximal	1	no	3.268	3.363	EPSD;PhosphoSitePlus	COSMIC	1.787	Up-regulation
TK_Tec_BTK_Y	P58753	TIRAP	Q06187	BTK	Y106	S105F	105	Missense	proximal	-1	no	2.946	2.478	PhosphoSitePlus;EPSD	COSMIC	1.787	Down-regulation
TK_Tec_BTK_Y	P58753	TIRAP	Q06187	BTK	Y106	S105Y	105	Missense	proximal	-1	no	2.946	2.068	PhosphoSitePlus;EPSD	COSMIC	1.787	Down-regulation
TK_Tec_BTK_Y	P58753	TIRAP	Q06187	BTK	Y187	M194T	194	Missense	distal	7	no	3.246	3.177	EPSD;PhosphoSitePlus	COSMIC;GDSC;CCLE	1.787	Down-regulation
TK_Tec_BTK_Y	Q06187	BTK	Q06187	BTK	Y134	Q127K	127	Missense	distal	-7	no	1.560	1.882	EPSD	COSMIC	1.787	Gain
TK_Tec_BTK_Y	Q06187	BTK	Q06187	BTK	Y223	L222F	222	Missense	proximal	-1	no	3.703	2.462	PhosphoSitePlus;EPSD	COSMIC	1.787	Down-regulation
TK_Tec_BTK_Y	Q06187	BTK	Q06187	BTK	Y223	D224N	224	Missense	proximal	1	no	3.703	3.569	PhosphoSitePlus;EPSD	COSMIC	1.787	Down-regulation
TK_Tec_BTK_Y	Q06187	BTK	Q06187	BTK	Y223	K217R	217	Missense	distal	-6	no	3.703	3.725	PhosphoSitePlus;EPSD	COSMIC	1.787	Up-regulation
TK_Tec_BTK_Y	Q06187	BTK	Q06187	BTK	Y241	D239Y	239	Missense	proximal	-2	no	1.825	1.895	EPSD	COSMIC	1.787	Up-regulation
TK_Tec_BTK_Y	Q06187	BTK	Q06187	BTK	Y241	S247N	247	Missense	distal	6	no	1.825	1.666	EPSD	COSMIC	1.787	Loss
TK_Tec_BTK_Y	Q06187	BTK	Q06187	BTK	Y241	F242V	242	Missense	proximal	1	no	1.825	1.862	EPSD	COSMIC	1.787	Up-regulation
TK_Tec_BTK_Y	Q06187	BTK	Q06187	BTK	Y551	L547Q	547	Missense	distal	-4	no	2.892	2.906	EPSD;PhosphoSitePlus	COSMIC	1.787	Up-regulation
TK_Tec_BTK_Y	Q06187	BTK	Q06187	BTK	Y551	R544W	544	Missense	distal	-7	no	2.892	2.441	EPSD;PhosphoSitePlus	COSMIC	1.787	Down-regulation
TK_Tec_BTK_Y	Q06187	BTK	Q06187	BTK	Y551	S553R	553	Missense	proximal	2	no	2.892	2.826	EPSD;PhosphoSitePlus	COSMIC	1.787	Down-regulation
TK_Tec_BTK_Y	Q06187	BTK	Q06187	BTK	Y551	R544M	544	Missense	distal	-7	no	2.892	2.579	EPSD;PhosphoSitePlus	COSMIC	1.787	Down-regulation
TK_Tec_BTK_Y	Q06187	BTK	Q06187	BTK	Y551	E550K	550	Missense	proximal	-1	no	2.892	2.514	EPSD;PhosphoSitePlus	COSMIC	1.787	Down-regulation
TK_Tec_BTK_Y	Q06187	BTK	Q06187	BTK	Y617	R615C	615	Missense	proximal	-2	no	1.915	1.963	EPSD	COSMIC	1.787	Up-regulation
TK_Tec_BTK_Y	Q08881	ITK	Q06187	BTK	Y180	E173A	173	Missense	distal	-7	no	4.386	4.451	PhosphoSitePlus	COSMIC	1.787	Up-regulation
TK_Tec_BTK_Y	Q08881	ITK	Q06187	BTK	Y180	P187S	187	Missense	distal	7	no	4.386	4.513	PhosphoSitePlus	COSMIC	1.787	Up-regulation
TK_Tec_BTK_Y	P51813	BMX	Q06187	BTK	Y216	T211P	211	Missense	distal	-5	no	3.101	3.040	PhosphoSitePlus	COSMIC	1.787	Down-regulation
TK_Tec_BTK_Y	P51813	BMX	Q06187	BTK	Y216	S220L	220	Missense	distal	4	no	3.101	3.089	PhosphoSitePlus	COSMIC	1.787	Down-regulation
TK_Tec_BTK_Y	P51813	BMX	Q06187	BTK	Y224	S220L	220	Missense	distal	-4	no	3.767	3.772	EPSD	COSMIC	1.787	Up-regulation
TK_Tec_BTK_Y	P51813	BMX	Q06187	BTK	Y224	S226F	226	Missense	proximal	2	no	3.767	3.710	EPSD	COSMIC	1.787	Down-regulation
TKL_IRAK_IRAK4_ST	Q96FA3	PELI1	Q9NWZ3	IRAK4	S70	A66V	66	Missense	distal	-4	no	171.120	183.686	EPSD;PhosphoSitePlus	COSMIC;CCLE	132.233	Up-regulation
TKL_IRAK_IRAK4_ST	Q96FA3	PELI1	Q9NWZ3	IRAK4	S70	P63L	63	Missense	distal	-7	no	171.120	150.419	EPSD;PhosphoSitePlus	COSMIC	132.233	Down-regulation
TKL_IRAK_IRAK4_ST	Q96FA3	PELI1	Q9NWZ3	IRAK4	T86	E90D	90	Missense	distal	4	no	195.317	185.987	EPSD;PhosphoSitePlus	COSMIC	132.233	Down-regulation
TKL_IRAK_IRAK4_ST	Q96FA3	PELI1	Q9NWZ3	IRAK4	T127	S123R	123	Missense	distal	-4	no	207.540	214.660	EPSD;PhosphoSitePlus	COSMIC	132.233	Up-regulation
TKL_IRAK_IRAK4_ST	Q96FA3	PELI1	Q9NWZ3	IRAK4	S293	R296K	296	Missense	distal	3	no	169.983	166.537	EPSD;PhosphoSitePlus	COSMIC	132.233	Down-regulation
TKL_IRAK_IRAK4_ST	P51617	IRAK1	Q9NWZ3	IRAK4	S375	G369V	369	Missense	distal	-6	no	118.821	153.394	EPSD	COSMIC	132.233	Gain
TKL_IRAK_IRAK4_ST	P51617	IRAK1	Q9NWZ3	IRAK4	S376	G369V	369	Missense	distal	-7	no	184.823	192.922	EPSD;PhosphoSitePlus	COSMIC	132.233	Up-regulation
TKL_IRAK_IRAK4_ST	P51617	IRAK1	Q9NWZ3	IRAK4	S376	R380W	380	Missense	distal	4	no	184.823	166.650	EPSD;PhosphoSitePlus	COSMIC	132.233	Down-regulation
TKL_IRAK_IRAK4_ST	P51617	IRAK1	Q9NWZ3	IRAK4	T381	R380W	380	Missense	proximal	-1	no	170.123	171.154	EPSD	COSMIC	132.233	Up-regulation
TKL_IRAK_IRAK4_ST	P51617	IRAK1	Q9NWZ3	IRAK4	T387	E393K	393	Missense	distal	6	no	205.395	219.741	PhosphoSitePlus;EPSD	COSMIC;GDSC;CCLE	132.233	Up-regulation
TKL_IRAK_IRAK4_ST	P51617	IRAK1	Q9NWZ3	IRAK4	T387	P392L	392	Missense	distal	5	no	205.395	191.192	PhosphoSitePlus;EPSD	COSMIC	132.233	Down-regulation
TKL_IRAK_IRAK4_ST	P51617	IRAK1	Q9NWZ3	IRAK4	T387	R380W	380	Missense	distal	-7	no	205.395	190.176	PhosphoSitePlus;EPSD	COSMIC	132.233	Down-regulation
TKL_IRAK_IRAK4_ST	Q9NWZ3	IRAK4	Q9NWZ3	IRAK4	S114	E116Q	116	Missense	proximal	2	no	208.867	212.847	EPSD;PhosphoSitePlus	COSMIC	132.233	Up-regulation
TKL_IRAK_IRAK4_ST	Q9NWZ3	IRAK4	Q9NWZ3	IRAK4	S114	T119P	119	Missense	distal	5	no	208.867	200.289	EPSD;PhosphoSitePlus	COSMIC	132.233	Down-regulation
TKL_IRAK_IRAK4_ST	Q9NWZ3	IRAK4	Q9NWZ3	IRAK4	S114	I118V	118	Missense	distal	4	no	208.867	220.496	EPSD;PhosphoSitePlus	COSMIC	132.233	Up-regulation
TKL_IRAK_IRAK4_ST	Q9NWZ3	IRAK4	Q9NWZ3	IRAK4	S150	P148A	148	Missense	proximal	-2	no	169.510	170.274	EPSD;PhosphoSitePlus	COSMIC	132.233	Up-regulation
TKL_IRAK_IRAK4_ST	Q9NWZ3	IRAK4	Q9NWZ3	IRAK4	S150	M146I	146	Missense	distal	-4	no	169.510	146.462	EPSD;PhosphoSitePlus	COSMIC	132.233	Down-regulation
TKL_IRAK_IRAK4_ST	Q9NWZ3	IRAK4	Q9NWZ3	IRAK4	S151	P148A	148	Missense	distal	-3	no	174.237	175.558	EPSD;PhosphoSitePlus	COSMIC	132.233	Up-regulation
TKL_IRAK_IRAK4_ST	Q9NWZ3	IRAK4	Q9NWZ3	IRAK4	S151	M146I	146	Missense	distal	-5	no	174.237	167.013	EPSD;PhosphoSitePlus	COSMIC	132.233	Down-regulation
TKL_IRAK_IRAK4_ST	Q9NWZ3	IRAK4	Q9NWZ3	IRAK4	S152	P148A	148	Missense	distal	-4	no	174.796	158.688	EPSD;PhosphoSitePlus	COSMIC	132.233	Down-regulation
TKL_IRAK_IRAK4_ST	Q9NWZ3	IRAK4	Q9NWZ3	IRAK4	S152	M146I	146	Missense	distal	-6	no	174.796	166.823	EPSD;PhosphoSitePlus	COSMIC	132.233	Down-regulation
TKL_IRAK_IRAK4_ST	Q9NWZ3	IRAK4	Q9NWZ3	IRAK4	S152	E159Q	159	Missense	distal	7	no	174.796	178.944	EPSD;PhosphoSitePlus	COSMIC	132.233	Up-regulation
TKL_IRAK_IRAK4_ST	Q9NWZ3	IRAK4	Q9NWZ3	IRAK4	S157	E159Q	159	Missense	proximal	2	no	134.629	138.609	EPSD	COSMIC	132.233	Up-regulation
TKL_IRAK_IRAK4_ST	Q9NWZ3	IRAK4	Q9NWZ3	IRAK4	S157	R164C	164	Missense	distal	7	no	134.629	116.770	EPSD	COSMIC	132.233	Loss
TKL_IRAK_IRAK4_ST	Q9NWZ3	IRAK4	Q9NWZ3	IRAK4	S157	D162N	162	Missense	distal	5	no	134.629	153.611	EPSD	COSMIC	132.233	Up-regulation
TKL_IRAK_IRAK4_ST	Q9NWZ3	IRAK4	Q9NWZ3	IRAK4	S157	R164T	164	Missense	distal	7	no	134.629	141.511	EPSD	COSMIC	132.233	Up-regulation
TKL_IRAK_IRAK4_ST	Q9NWZ3	IRAK4	Q9NWZ3	IRAK4	T342	Q341K	341	Missense	proximal	-1	no	199.999	199.452	EPSD;PhosphoSitePlus	COSMIC	132.233	Down-regulation
TKL_IRAK_IRAK4_ST	Q9NWZ3	IRAK4	Q9NWZ3	IRAK4	T342	A340T	340	Missense	proximal	-2	no	199.999	203.441	EPSD;PhosphoSitePlus	COSMIC	132.233	Up-regulation
TKL_IRAK_IRAK4_ST	Q9NWZ3	IRAK4	Q9NWZ3	IRAK4	T345	Q341K	341	Missense	distal	-4	no	160.697	159.351	EPSD;PhosphoSitePlus	COSMIC	132.233	Down-regulation
TKL_IRAK_IRAK4_ST	Q9NWZ3	IRAK4	Q9NWZ3	IRAK4	T345	A340T	340	Missense	distal	-5	no	160.697	166.934	EPSD;PhosphoSitePlus	COSMIC	132.233	Up-regulation
TKL_IRAK_IRAK4_ST	Q9NWZ3	IRAK4	Q9NWZ3	IRAK4	S346	Q341K	341	Missense	distal	-5	no	196.241	197.486	EPSD;PhosphoSitePlus	COSMIC	132.233	Up-regulation
TKL_IRAK_IRAK4_ST	Q9NWZ3	IRAK4	Q9NWZ3	IRAK4	S346	A340T	340	Missense	distal	-6	no	196.241	201.787	EPSD;PhosphoSitePlus	COSMIC	132.233	Up-regulation
TKL_IRAK_IRAK4_ST	Q9NWZ3	IRAK4	Q9NWZ3	IRAK4	T352	M355I	355	Missense	distal	3	no	150.820	140.682	EPSD;PhosphoSitePlus	COSMIC	132.233	Down-regulation
TKL_IRAK_IRAK4_ST	Q9NWZ3	IRAK4	Q9NWZ3	IRAK4	T352	M355V	355	Missense	distal	3	no	150.820	158.748	EPSD;PhosphoSitePlus	COSMIC	132.233	Up-regulation
TKL_IRAK_IRAK4_ST	Q9NWZ3	IRAK4	Q9NWZ3	IRAK4	S423	A428T	428	Missense	distal	5	no	140.113	155.066	EPSD	COSMIC	132.233	Up-regulation
TKL_IRAK_IRAK4_ST	Q9NWZ3	IRAK4	Q9NWZ3	IRAK4	S423	A428V	428	Missense	distal	5	no	140.113	151.938	EPSD	COSMIC	132.233	Up-regulation
TKL_IRAK_IRAK4_ST	Q9NWZ3	IRAK4	Q9NWZ3	IRAK4	S425	A428T	428	Missense	distal	3	no	115.942	138.052	EPSD	COSMIC	132.233	Gain
TKL_IRAK_IRAK4_ST	P14598	NCF1	Q9NWZ3	IRAK4	T133	T138K	138	Missense	distal	5	no	213.222	221.803	EPSD;PhosphoSitePlus	COSMIC	132.233	Up-regulation
TKL_IRAK_IRAK4_ST	P14598	NCF1	Q9NWZ3	IRAK4	T138	T138K	138	Missense	central	0	yes	227.545	0.000	EPSD;PhosphoSitePlus	COSMIC	132.233	Loss
TKL_IRAK_IRAK4_ST	P14598	NCF1	Q9NWZ3	IRAK4	T138	D144E	144	Missense	distal	6	no	227.545	257.999	EPSD;PhosphoSitePlus	COSMIC	132.233	Up-regulation
TKL_IRAK_IRAK4_ST	P14598	NCF1	Q9NWZ3	IRAK4	S173	N166D	166	Missense	distal	-7	no	148.443	130.616	EPSD	COSMIC	132.233	Loss
TKL_IRAK_IRAK4_ST	P14598	NCF1	Q9NWZ3	IRAK4	S173	E174K	174	Missense	proximal	1	no	148.443	153.376	EPSD	COSMIC	132.233	Up-regulation
TKL_IRAK_IRAK4_ST	P14598	NCF1	Q9NWZ3	IRAK4	T179	E174K	174	Missense	distal	-5	no	125.316	136.691	EPSD	COSMIC	132.233	Gain
TKL_IRAK_IRAK4_ST	P14598	NCF1	Q9NWZ3	IRAK4	S288	V287A	287	Missense	proximal	-1	no	186.376	187.011	EPSD;PhosphoSitePlus	COSMIC	132.233	Up-regulation
TKL_IRAK_IRAK4_ST	P14598	NCF1	Q9NWZ3	IRAK4	S345	P349R	349	Missense	distal	4	no	185.713	189.855	EPSD;PhosphoSitePlus	COSMIC	132.233	Up-regulation
TKL_IRAK_IRAK4_ST	P14598	NCF1	Q9NWZ3	IRAK4	S348	P349R	349	Missense	proximal	1	no	178.847	181.759	PhosphoSitePlus;EPSD	COSMIC	132.233	Up-regulation
TKL_IRAK_IRAK4_ST	P14598	NCF1	Q9NWZ3	IRAK4	T356	P349R	349	Missense	distal	-7	no	159.483	157.479	EPSD;PhosphoSitePlus	COSMIC	132.233	Down-regulation
CK1_TTBK_TTBK1_ST	P10636	MAPT	Q5TCY1	TTBK1	S228	S227N	227	Missense	proximal	-1	no	11.654	11.427	EPSD	COSMIC	7.699	Down-regulation
CK1_TTBK_TTBK1_ST	P10636	MAPT	Q5TCY1	TTBK1	S228	S227I	227	Missense	proximal	-1	no	11.654	11.662	EPSD	COSMIC	7.699	Up-regulation
CK1_TTBK_TTBK1_ST	P10636	MAPT	Q5TCY1	TTBK1	S228	E226K	226	Missense	proximal	-2	no	11.654	11.653	EPSD	COSMIC	7.699	Down-regulation
CK1_TTBK_TTBK1_ST	P10636	MAPT	Q5TCY1	TTBK1	S228	Q230R	230	Missense	proximal	2	no	11.654	11.691	EPSD	COSMIC	7.699	Up-regulation
CK1_TTBK_TTBK1_ST	P10636	MAPT	Q5TCY1	TTBK1	S228	P233S	233	Missense	distal	5	no	11.654	11.749	EPSD	COSMIC	7.699	Up-regulation
CK1_TTBK_TTBK1_ST	P10636	MAPT	Q5TCY1	TTBK1	S228	D225E	225	Missense	distal	-3	no	11.654	11.598	EPSD	COSMIC	7.699	Down-regulation
CK1_TTBK_TTBK1_ST	P10636	MAPT	Q5TCY1	TTBK1	S228	S227G	227	Missense	proximal	-1	no	11.654	11.266	EPSD	COSMIC	7.699	Down-regulation
CK1_TTBK_TTBK1_ST	P10636	MAPT	Q5TCY1	TTBK1	S228	S235L	235	Missense	distal	7	no	11.654	11.374	EPSD	COSMIC	7.699	Down-regulation
CK1_TTBK_TTBK1_ST	P10636	MAPT	Q5TCY1	TTBK1	S238	A237T	237	Missense	proximal	-1	no	11.337	11.405	EPSD	COSMIC	7.699	Up-regulation
CK1_TTBK_TTBK1_ST	P10636	MAPT	Q5TCY1	TTBK1	S238	A240S	240	Missense	proximal	2	no	11.337	11.350	EPSD	COSMIC	7.699	Up-regulation
CK1_TTBK_TTBK1_ST	P10636	MAPT	Q5TCY1	TTBK1	S238	D242N	242	Missense	distal	4	no	11.337	10.782	EPSD	COSMIC	7.699	Down-regulation
CK1_TTBK_TTBK1_ST	P10636	MAPT	Q5TCY1	TTBK1	S238	R244W	244	Missense	distal	6	no	11.337	11.903	EPSD	COSMIC	7.699	Up-regulation
CK1_TTBK_TTBK1_ST	P10636	MAPT	Q5TCY1	TTBK1	S238	S238P	238	Missense	central	0	yes	11.337	0.000	EPSD	COSMIC	7.699	Loss
CK1_TTBK_TTBK1_ST	P10636	MAPT	Q5TCY1	TTBK1	S238	P233S	233	Missense	distal	-5	no	11.337	11.171	EPSD	COSMIC	7.699	Down-regulation
CK1_TTBK_TTBK1_ST	P10636	MAPT	Q5TCY1	TTBK1	S238	S238F	238	Missense	central	0	yes	11.337	0.000	EPSD	COSMIC	7.699	Loss
CK1_TTBK_TTBK1_ST	P10636	MAPT	Q5TCY1	TTBK1	S238	G243D	243	Missense	distal	5	no	11.337	11.300	EPSD	COSMIC	7.699	Down-regulation
CK1_TTBK_TTBK1_ST	P10636	MAPT	Q5TCY1	TTBK1	S238	S235L	235	Missense	distal	-3	no	11.337	11.263	EPSD	COSMIC	7.699	Down-regulation
CK1_TTBK_TTBK1_ST	P10636	MAPT	Q5TCY1	TTBK1	S382	G385V	385	Missense	distal	3	no	9.123	8.820	EPSD	COSMIC	7.699	Down-regulation
CK1_TTBK_TTBK1_ST	P10636	MAPT	Q5TCY1	TTBK1	S382	T386I	386	Missense	distal	4	no	9.123	8.979	EPSD	COSMIC	7.699	Down-regulation
CK1_TTBK_TTBK1_ST	P10636	MAPT	Q5TCY1	TTBK1	S382	R377W	377	Missense	distal	-5	no	9.123	8.881	EPSD	COSMIC	7.699	Down-regulation
CK1_TTBK_TTBK1_ST	P10636	MAPT	Q5TCY1	TTBK1	S382	D389N	389	Missense	distal	7	no	9.123	9.239	EPSD	COSMIC;GDSC;CCLE	7.699	Up-regulation
CK1_TTBK_TTBK1_ST	P10636	MAPT	Q5TCY1	TTBK1	S396	R398C	398	Missense	proximal	2	no	11.125	11.097	EPSD	COSMIC	7.699	Down-regulation
CK1_TTBK_TTBK1_ST	P10636	MAPT	Q5TCY1	TTBK1	S396	S396F	396	Missense	central	0	yes	11.125	0.000	EPSD	COSMIC	7.699	Loss
CK1_TTBK_TTBK1_ST	P10636	MAPT	Q5TCY1	TTBK1	S396	D389N	389	Missense	distal	-7	no	11.125	10.712	EPSD	COSMIC;GDSC;CCLE	7.699	Down-regulation
CK1_TTBK_TTBK1_ST	P10636	MAPT	Q5TCY1	TTBK1	T403	L410F	410	Missense	distal	7	no	7.586	7.799	EPSD	COSMIC	7.699	Gain
CK1_TTBK_TTBK1_ST	P10636	MAPT	Q5TCY1	TTBK1	S411	L410F	410	Missense	proximal	-1	no	10.521	10.314	EPSD	COSMIC	7.699	Down-regulation
CK1_TTBK_TTBK1_ST	P10636	MAPT	Q5TCY1	TTBK1	S411	P412S	412	Missense	proximal	1	no	10.521	5.110	EPSD	COSMIC	7.699	Loss
CK1_TTBK_TTBK1_ST	P10636	MAPT	Q5TCY1	TTBK1	S502	P506S	506	Missense	distal	4	no	8.048	7.824	EPSD	COSMIC	7.699	Down-regulation
CK1_TTBK_TTBK1_ST	P10636	MAPT	Q5TCY1	TTBK1	S502	A495T	495	Missense	distal	-7	no	8.048	6.916	EPSD	COSMIC	7.699	Loss
CK1_TTBK_TTBK1_ST	P10636	MAPT	Q5TCY1	TTBK1	S502	G509V	509	Missense	distal	7	no	8.048	7.737	EPSD	COSMIC	7.699	Down-regulation
CK1_TTBK_TTBK1_ST	P10636	MAPT	Q5TCY1	TTBK1	S502	P506L	506	Missense	distal	4	no	8.048	7.768	EPSD	COSMIC	7.699	Down-regulation
CK1_TTBK_TTBK1_ST	P10636	MAPT	Q5TCY1	TTBK1	S508	P506S	506	Missense	proximal	-2	no	11.808	11.652	EPSD	COSMIC	7.699	Down-regulation
CK1_TTBK_TTBK1_ST	P10636	MAPT	Q5TCY1	TTBK1	S508	R511C	511	Missense	distal	3	no	11.808	11.680	EPSD	COSMIC;CCLE	7.699	Down-regulation
CK1_TTBK_TTBK1_ST	P10636	MAPT	Q5TCY1	TTBK1	S508	G509V	509	Missense	proximal	1	no	11.808	10.857	EPSD	COSMIC	7.699	Down-regulation
CK1_TTBK_TTBK1_ST	P10636	MAPT	Q5TCY1	TTBK1	S508	P506L	506	Missense	proximal	-2	no	11.808	11.747	EPSD	COSMIC	7.699	Down-regulation
CK1_TTBK_TTBK1_ST	P10636	MAPT	Q5TCY1	TTBK1	S512	P506S	506	Missense	distal	-6	no	11.085	12.425	EPSD	COSMIC	7.699	Up-regulation
CK1_TTBK_TTBK1_ST	P10636	MAPT	Q5TCY1	TTBK1	S512	G518V	518	Missense	distal	6	no	11.085	11.972	EPSD	COSMIC	7.699	Up-regulation
CK1_TTBK_TTBK1_ST	P10636	MAPT	Q5TCY1	TTBK1	S512	R511C	511	Missense	proximal	-1	no	11.085	10.962	EPSD	COSMIC;CCLE	7.699	Down-regulation
CK1_TTBK_TTBK1_ST	P10636	MAPT	Q5TCY1	TTBK1	S512	G509V	509	Missense	distal	-3	no	11.085	11.113	EPSD	COSMIC	7.699	Up-regulation
CK1_TTBK_TTBK1_ST	P10636	MAPT	Q5TCY1	TTBK1	S512	P506L	506	Missense	distal	-6	no	11.085	10.992	EPSD	COSMIC	7.699	Down-regulation
CK1_TTBK_TTBK1_ST	P10636	MAPT	Q5TCY1	TTBK1	S515	G521V	521	Missense	distal	6	no	14.725	15.611	EPSD	COSMIC	7.699	Up-regulation
CK1_TTBK_TTBK1_ST	P10636	MAPT	Q5TCY1	TTBK1	S515	G518V	518	Missense	distal	3	no	14.725	14.421	EPSD	COSMIC	7.699	Down-regulation
CK1_TTBK_TTBK1_ST	P10636	MAPT	Q5TCY1	TTBK1	S515	R511C	511	Missense	distal	-4	no	14.725	14.692	EPSD	COSMIC;CCLE	7.699	Down-regulation
CK1_TTBK_TTBK1_ST	P10636	MAPT	Q5TCY1	TTBK1	S515	G509V	509	Missense	distal	-6	no	14.725	14.374	EPSD	COSMIC	7.699	Down-regulation
CK1_TTBK_TTBK1_ST	P10636	MAPT	Q5TCY1	TTBK1	S516	G521V	521	Missense	distal	5	no	14.085	14.199	EPSD	COSMIC	7.699	Up-regulation
CK1_TTBK_TTBK1_ST	P10636	MAPT	Q5TCY1	TTBK1	S516	G518V	518	Missense	proximal	2	no	14.085	14.114	EPSD	COSMIC	7.699	Up-regulation
CK1_TTBK_TTBK1_ST	P10636	MAPT	Q5TCY1	TTBK1	S516	R511C	511	Missense	distal	-5	no	14.085	13.870	EPSD	COSMIC;CCLE	7.699	Down-regulation
CK1_TTBK_TTBK1_ST	P10636	MAPT	Q5TCY1	TTBK1	S516	G509V	509	Missense	distal	-7	no	14.085	14.872	EPSD	COSMIC	7.699	Up-regulation
CK1_TTBK_TTBK1_ST	P10636	MAPT	Q5TCY1	TTBK1	S519	G521V	521	Missense	proximal	2	no	19.267	19.296	EPSD	COSMIC	7.699	Up-regulation
CK1_TTBK_TTBK1_ST	P10636	MAPT	Q5TCY1	TTBK1	S519	R526H	526	Missense	distal	7	no	19.267	19.549	EPSD	COSMIC	7.699	Up-regulation
CK1_TTBK_TTBK1_ST	P10636	MAPT	Q5TCY1	TTBK1	S519	G518V	518	Missense	proximal	-1	no	19.267	19.424	EPSD	COSMIC	7.699	Up-regulation
CK1_TTBK_TTBK1_ST	P10636	MAPT	Q5TCY1	TTBK1	T522	G521V	521	Missense	proximal	-1	no	12.073	12.229	EPSD	COSMIC	7.699	Up-regulation
CK1_TTBK_TTBK1_ST	P10636	MAPT	Q5TCY1	TTBK1	T522	R526H	526	Missense	distal	4	no	12.073	12.317	EPSD	COSMIC	7.699	Up-regulation
CK1_TTBK_TTBK1_ST	P10636	MAPT	Q5TCY1	TTBK1	T522	G518V	518	Missense	distal	-4	no	12.073	12.024	EPSD	COSMIC	7.699	Down-regulation
CK1_TTBK_TTBK1_ST	P10636	MAPT	Q5TCY1	TTBK1	T522	R528S	528	Missense	distal	6	no	12.073	13.928	EPSD	COSMIC	7.699	Up-regulation
CK1_TTBK_TTBK1_ST	P10636	MAPT	Q5TCY1	TTBK1	S525	R526H	526	Missense	proximal	1	no	7.425	9.053	EPSD	COSMIC	7.699	Gain
CK1_TTBK_TTBK1_ST	P10636	MAPT	Q5TCY1	TTBK1	S525	G518V	518	Missense	distal	-7	no	7.425	8.212	EPSD	COSMIC	7.699	Gain
CK1_TTBK_TTBK1_ST	P10636	MAPT	Q5TCY1	TTBK1	T529	R526H	526	Missense	distal	-3	no	11.833	11.862	EPSD	COSMIC	7.699	Up-regulation
CK1_TTBK_TTBK1_ST	P10636	MAPT	Q5TCY1	TTBK1	T529	R528S	528	Missense	proximal	-1	no	11.833	11.851	EPSD	COSMIC	7.699	Up-regulation
CK1_TTBK_TTBK1_ST	P10636	MAPT	Q5TCY1	TTBK1	T529	P530S	530	Missense	proximal	1	no	11.833	6.422	EPSD	COSMIC	7.699	Loss
CK1_TTBK_TTBK1_ST	P10636	MAPT	Q5TCY1	TTBK1	T529	P536H	536	Missense	distal	7	no	11.833	11.990	EPSD	COSMIC	7.699	Up-regulation
CK1_TTBK_TTBK1_ST	P10636	MAPT	Q5TCY1	TTBK1	T529	P535Q	535	Missense	distal	6	no	11.833	12.146	EPSD	COSMIC	7.699	Up-regulation
CK1_TTBK_TTBK1_ST	P10636	MAPT	Q5TCY1	TTBK1	T548	P550S	550	Missense	proximal	2	no	9.498	9.499	EPSD	COSMIC	7.699	Up-regulation
CK1_TTBK_TTBK1_ST	P10636	MAPT	Q5TCY1	TTBK1	T548	P553R	553	Missense	distal	5	no	9.498	9.787	EPSD	COSMIC	7.699	Up-regulation
CK1_TTBK_TTBK1_ST	P10636	MAPT	Q5TCY1	TTBK1	T548	P553L	553	Missense	distal	5	no	9.498	9.685	EPSD	COSMIC	7.699	Up-regulation
CK1_TTBK_TTBK1_ST	P10636	MAPT	Q5TCY1	TTBK1	T548	P549L	549	Missense	proximal	1	no	9.498	6.633	EPSD	COSMIC	7.699	Loss
CK1_TTBK_TTBK1_ST	P10636	MAPT	Q5TCY1	TTBK1	T548	S555F	555	Missense	distal	7	no	9.498	9.431	EPSD	COSMIC	7.699	Down-regulation
CK1_TTBK_TTBK1_ST	P10636	MAPT	Q5TCY1	TTBK1	T548	P553Q	553	Missense	distal	5	no	9.498	9.540	EPSD	COSMIC	7.699	Up-regulation
CK1_TTBK_TTBK1_ST	P10636	MAPT	Q5TCY1	TTBK1	S552	P550S	550	Missense	proximal	-2	no	11.750	11.593	EPSD	COSMIC	7.699	Down-regulation
CK1_TTBK_TTBK1_ST	P10636	MAPT	Q5TCY1	TTBK1	S552	R559C	559	Missense	distal	7	no	11.750	11.993	EPSD	COSMIC	7.699	Up-regulation
CK1_TTBK_TTBK1_ST	P10636	MAPT	Q5TCY1	TTBK1	S552	P553R	553	Missense	proximal	1	no	11.750	5.540	EPSD	COSMIC	7.699	Loss
CK1_TTBK_TTBK1_ST	P10636	MAPT	Q5TCY1	TTBK1	S552	P553L	553	Missense	proximal	1	no	11.750	8.885	EPSD	COSMIC	7.699	Down-regulation
CK1_TTBK_TTBK1_ST	P10636	MAPT	Q5TCY1	TTBK1	S552	P549L	549	Missense	distal	-3	no	11.750	11.743	EPSD	COSMIC	7.699	Down-regulation
CK1_TTBK_TTBK1_ST	P10636	MAPT	Q5TCY1	TTBK1	S552	S555F	555	Missense	distal	3	no	11.750	11.975	EPSD	COSMIC	7.699	Up-regulation
CK1_TTBK_TTBK1_ST	P10636	MAPT	Q5TCY1	TTBK1	S552	P553Q	553	Missense	proximal	1	no	11.750	7.071	EPSD	COSMIC	7.699	Loss
CK1_TTBK_TTBK1_ST	P10636	MAPT	Q5TCY1	TTBK1	S555	P550S	550	Missense	distal	-5	no	8.530	8.364	EPSD	COSMIC	7.699	Down-regulation
CK1_TTBK_TTBK1_ST	P10636	MAPT	Q5TCY1	TTBK1	S555	R559C	559	Missense	distal	4	no	8.530	8.800	EPSD	COSMIC	7.699	Up-regulation
CK1_TTBK_TTBK1_ST	P10636	MAPT	Q5TCY1	TTBK1	S555	P553R	553	Missense	proximal	-2	no	8.530	8.359	EPSD	COSMIC	7.699	Down-regulation
CK1_TTBK_TTBK1_ST	P10636	MAPT	Q5TCY1	TTBK1	S555	P553L	553	Missense	proximal	-2	no	8.530	8.469	EPSD	COSMIC	7.699	Down-regulation
CK1_TTBK_TTBK1_ST	P10636	MAPT	Q5TCY1	TTBK1	S555	P549L	549	Missense	distal	-6	no	8.530	8.437	EPSD	COSMIC	7.699	Down-regulation
CK1_TTBK_TTBK1_ST	P10636	MAPT	Q5TCY1	TTBK1	S555	S555F	555	Missense	central	0	yes	8.530	0.000	EPSD	COSMIC	7.699	Loss
CK1_TTBK_TTBK1_ST	P10636	MAPT	Q5TCY1	TTBK1	S555	P553Q	553	Missense	proximal	-2	no	8.530	8.405	EPSD	COSMIC	7.699	Down-regulation
CK1_TTBK_TTBK1_ST	P10636	MAPT	Q5TCY1	TTBK1	S713	E708D	708	Missense	distal	-5	no	12.492	12.624	EPSD	COSMIC	7.699	Up-regulation
CK1_TTBK_TTBK1_ST	P10636	MAPT	Q5TCY1	TTBK1	S713	G706R	706	Missense	distal	-7	no	12.492	11.876	EPSD	COSMIC	7.699	Down-regulation
CK1_TTBK_TTBK1_ST	P10636	MAPT	Q5TCY1	TTBK1	S713	V710M	710	Missense	distal	-3	no	12.492	12.468	EPSD	COSMIC	7.699	Down-regulation
CK1_TTBK_TTBK1_ST	P10636	MAPT	Q5TCY1	TTBK1	S713	E708K	708	Missense	distal	-5	no	12.492	12.765	EPSD	COSMIC	7.699	Up-regulation
CK1_TTBK_TTBK1_ST	P10636	MAPT	Q5TCY1	TTBK1	S713	V710A	710	Missense	distal	-3	no	12.492	12.498	EPSD	COSMIC	7.699	Up-regulation
CK1_TTBK_TTBK1_ST	P10636	MAPT	Q5TCY1	TTBK1	S721	R723W	723	Missense	proximal	2	no	14.656	14.626	EPSD	COSMIC	7.699	Down-regulation
CK1_TTBK_TTBK1_ST	P10636	MAPT	Q5TCY1	TTBK1	S721	V728M	728	Missense	distal	7	no	14.656	14.644	EPSD	COSMIC	7.699	Down-regulation
CK1_TTBK_TTBK1_ST	P10636	MAPT	Q5TCY1	TTBK1	S721	V728A	728	Missense	distal	7	no	14.656	14.517	EPSD	COSMIC	7.699	Down-regulation
CK1_TTBK_TTBK1_ST	P10636	MAPT	Q5TCY1	TTBK1	S733	G732S	732	Missense	proximal	-1	no	12.247	12.636	EPSD	COSMIC	7.699	Up-regulation
CK1_TTBK_TTBK1_ST	P10636	MAPT	Q5TCY1	TTBK1	S733	D735N	735	Missense	proximal	2	no	12.247	12.274	EPSD	COSMIC	7.699	Up-regulation
CK1_TTBK_TTBK1_ST	P10636	MAPT	Q5TCY1	TTBK1	S733	G732C	732	Missense	proximal	-1	no	12.247	12.495	EPSD	COSMIC	7.699	Up-regulation
CK1_TTBK_TTBK1_ST	P10636	MAPT	Q5TCY1	TTBK1	S733	V728M	728	Missense	distal	-5	no	12.247	12.134	EPSD	COSMIC	7.699	Down-regulation
CK1_TTBK_TTBK1_ST	P10636	MAPT	Q5TCY1	TTBK1	S733	V728A	728	Missense	distal	-5	no	12.247	11.670	EPSD	COSMIC	7.699	Down-regulation
CK1_TTBK_TTBK1_ST	P10636	MAPT	Q5TCY1	TTBK1	S739	G732S	732	Missense	distal	-7	no	11.793	13.356	EPSD	COSMIC	7.699	Up-regulation
CK1_TTBK_TTBK1_ST	P10636	MAPT	Q5TCY1	TTBK1	S739	D735N	735	Missense	distal	-4	no	11.793	11.814	EPSD	COSMIC	7.699	Up-regulation
CK1_TTBK_TTBK1_ST	P10636	MAPT	Q5TCY1	TTBK1	S739	G732C	732	Missense	distal	-7	no	11.793	11.955	EPSD	COSMIC	7.699	Up-regulation
CK1_TTBK_TTBK1_ST	P10636	MAPT	Q5TCY1	TTBK1	S739	T744M	744	Missense	distal	5	no	11.793	11.764	EPSD	COSMIC	7.699	Down-regulation
CK1_TTBK_TTBK1_ST	P10636	MAPT	Q5TCY1	TTBK1	S739	A743T	743	Missense	distal	4	no	11.793	11.834	EPSD	COSMIC	7.699	Up-regulation
CK1_TTBK_TTBK1_ST	P10636	MAPT	Q5TCY1	TTBK1	T744	E748K	748	Missense	distal	4	no	10.882	10.829	EPSD	COSMIC	7.699	Down-regulation
CK1_TTBK_TTBK1_ST	P10636	MAPT	Q5TCY1	TTBK1	T744	T744M	744	Missense	central	0	yes	10.882	0.000	EPSD	COSMIC	7.699	Loss
CK1_TTBK_TTBK1_ST	P10636	MAPT	Q5TCY1	TTBK1	T744	A743T	743	Missense	proximal	-1	no	10.882	10.950	EPSD	COSMIC	7.699	Up-regulation
TKL_MLK_ZAK_MAP3K20_ST	Q9NYL2	MAP3K20	Q9NYL2	MAP3K20	T161	M164L	164	Missense	distal	3	no	7.367	7.310	EPSD;PhosphoSitePlus	COSMIC	2.674	Down-regulation
TKL_MLK_ZAK_MAP3K20_ST	Q9NYL2	MAP3K20	Q9NYL2	MAP3K20	T161	G168R	168	Missense	distal	7	no	7.367	7.438	EPSD;PhosphoSitePlus	COSMIC	2.674	Up-regulation
TKL_MLK_ZAK_MAP3K20_ST	Q9NYL2	MAP3K20	Q9NYL2	MAP3K20	S165	M164L	164	Missense	proximal	-1	no	7.793	7.693	EPSD;PhosphoSitePlus	COSMIC	2.674	Down-regulation
TKL_MLK_ZAK_MAP3K20_ST	Q9NYL2	MAP3K20	Q9NYL2	MAP3K20	S165	F170L	170	Missense	distal	5	no	7.793	8.115	EPSD;PhosphoSitePlus	COSMIC	2.674	Up-regulation
TKL_MLK_ZAK_MAP3K20_ST	Q9NYL2	MAP3K20	Q9NYL2	MAP3K20	S165	G168R	168	Missense	distal	3	no	7.793	7.535	EPSD;PhosphoSitePlus	COSMIC	2.674	Down-regulation
TKL_MLK_ZAK_MAP3K20_ST	Q9NYL2	MAP3K20	Q9NYL2	MAP3K20	T586	R580Q	580	Missense	distal	-6	no	2.877	2.425	EPSD	COSMIC	2.674	Loss
TKL_MLK_ZAK_MAP3K20_ST	Q9NYL2	MAP3K20	Q9NYL2	MAP3K20	T586	R590H	590	Missense	distal	4	no	2.877	2.668	EPSD	COSMIC	2.674	Loss
TKL_MLK_ZAK_MAP3K20_ST	Q9NYL2	MAP3K20	Q9NYL2	MAP3K20	T586	N585D	585	Missense	proximal	-1	no	2.877	3.017	EPSD	COSMIC	2.674	Up-regulation
TKL_MLK_ZAK_MAP3K20_ST	Q9NYL2	MAP3K20	Q9NYL2	MAP3K20	T586	R580W	580	Missense	distal	-6	no	2.877	2.387	EPSD	COSMIC	2.674	Loss
TKL_MLK_ZAK_MAP3K20_ST	Q9NYL2	MAP3K20	Q9NYL2	MAP3K20	T666	Y673N	673	Missense	distal	7	no	2.880	2.928	EPSD	COSMIC	2.674	Up-regulation
TKL_MLK_ZAK_MAP3K20_ST	Q9NYL2	MAP3K20	Q9NYL2	MAP3K20	T666	S668L	668	Missense	proximal	2	no	2.880	2.891	EPSD	COSMIC	2.674	Up-regulation
TKL_MLK_ZAK_MAP3K20_ST	Q9NYL2	MAP3K20	Q9NYL2	MAP3K20	T666	E669K	669	Missense	distal	3	no	2.880	2.963	EPSD	COSMIC	2.674	Up-regulation
TKL_MLK_ZAK_MAP3K20_ST	Q9NYL2	MAP3K20	Q9NYL2	MAP3K20	T666	E669Q	669	Missense	distal	3	no	2.880	2.457	EPSD	COSMIC	2.674	Loss
TKL_MLK_ZAK_MAP3K20_ST	Q9NYL2	MAP3K20	Q9NYL2	MAP3K20	T666	S667F	667	Missense	proximal	1	no	2.880	2.903	EPSD	COSMIC	2.674	Up-regulation
TKL_MLK_ZAK_MAP3K20_ST	Q9NYL2	MAP3K20	Q9NYL2	MAP3K20	S690	S685G	685	Missense	distal	-5	no	2.448	3.207	EPSD	COSMIC	2.674	Gain
TKL_MLK_ZAK_MAP3K20_ST	Q9NYL2	MAP3K20	Q9NYL2	MAP3K20	S718	L722F	722	Missense	distal	4	no	3.077	2.925	EPSD	COSMIC	2.674	Down-regulation
TKL_MLK_ZAK_MAP3K20_ST	Q9NYL2	MAP3K20	Q9NYL2	MAP3K20	S718	H725D	725	Missense	distal	7	no	3.077	2.802	EPSD	COSMIC	2.674	Down-regulation
TKL_MLK_ZAK_MAP3K20_ST	Q9NYL2	MAP3K20	Q9NYL2	MAP3K20	S764	T769K	769	Missense	distal	5	no	3.821	3.666	EPSD	COSMIC	2.674	Down-regulation
TKL_MLK_ZAK_MAP3K20_ST	Q9NYL2	MAP3K20	Q9NYL2	MAP3K20	S764	G767S	767	Missense	distal	3	no	3.821	3.006	EPSD	COSMIC	2.674	Down-regulation
TKL_MLK_ZAK_MAP3K20_ST	Q9NYL2	MAP3K20	Q9NYL2	MAP3K20	S764	E759D	759	Missense	distal	-5	no	3.821	3.868	EPSD	COSMIC	2.674	Up-regulation
TKL_MLK_ZAK_MAP3K20_ST	O96017	CHEK2	Q9NYL2	MAP3K20	S62	Q69R	69	Missense	distal	7	no	2.593	2.842	EPSD	COSMIC	2.674	Gain
TKL_MLK_ZAK_MAP3K20_ST	O96017	CHEK2	Q9NYL2	MAP3K20	T68	Q69R	69	Missense	proximal	1	no	7.577	7.567	PhosphoSitePlus	COSMIC	2.674	Down-regulation
TKL_MLK_ZAK_MAP3K20_ST	O96017	CHEK2	Q9NYL2	MAP3K20	S140	R145L	145	Missense	distal	5	no	2.477	2.681	EPSD	COSMIC	2.674	Gain
TKL_MLK_ZAK_MAP3K20_ST	O96017	CHEK2	Q9NYL2	MAP3K20	S210	D203N	203	Missense	distal	-7	no	2.499	2.740	EPSD	COSMIC	2.674	Gain
TKL_MLK_ZAK_MAP3K20_ST	O96017	CHEK2	Q9NYL2	MAP3K20	S210	T205I	205	Missense	distal	-5	no	2.499	2.715	EPSD	COSMIC	2.674	Gain
TKL_MLK_ZAK_MAP3K20_ST	O96017	CHEK2	Q9NYL2	MAP3K20	T383	M381I	381	Missense	proximal	-2	no	2.532	2.761	EPSD	COSMIC	2.674	Gain
TKL_MLK_ZAK_MAP3K20_ST	O96017	CHEK2	Q9NYL2	MAP3K20	T383	M381V	381	Missense	proximal	-2	no	2.532	2.953	EPSD	COSMIC	2.674	Gain
TKL_MLK_ZAK_MAP3K20_ST	O96017	CHEK2	Q9NYL2	MAP3K20	T383	S379C	379	Missense	distal	-4	no	2.532	2.840	EPSD	COSMIC	2.674	Gain
TKL_MLK_ZAK_MAP3K20_ST	O96017	CHEK2	Q9NYL2	MAP3K20	S435	K437Q	437	Missense	proximal	2	no	3.094	3.004	EPSD	COSMIC	2.674	Down-regulation
TKL_MLK_ZAK_MAP3K20_ST	O96017	CHEK2	Q9NYL2	MAP3K20	S435	T441I	441	Missense	distal	6	no	3.094	3.143	EPSD	COSMIC	2.674	Up-regulation
TKL_MLK_ZAK_MAP3K20_ST	O96017	CHEK2	Q9NYL2	MAP3K20	T441	I448S	448	Missense	distal	7	no	3.549	3.109	EPSD	COSMIC	2.674	Down-regulation
TKL_MLK_ZAK_MAP3K20_ST	O96017	CHEK2	Q9NYL2	MAP3K20	T441	K437Q	437	Missense	distal	-4	no	3.549	3.254	EPSD	COSMIC	2.674	Down-regulation
TKL_MLK_ZAK_MAP3K20_ST	O96017	CHEK2	Q9NYL2	MAP3K20	T441	I448T	448	Missense	distal	7	no	3.549	3.336	EPSD	COSMIC	2.674	Down-regulation
TKL_MLK_ZAK_MAP3K20_ST	O96017	CHEK2	Q9NYL2	MAP3K20	T441	T441I	441	Missense	central	0	yes	3.549	0.000	EPSD	COSMIC	2.674	Loss
TKL_MLK_ZAK_MAP3K20_ST	O96017	CHEK2	Q9NYL2	MAP3K20	T441	G443V	443	Missense	proximal	2	no	3.549	3.740	EPSD	COSMIC	2.674	Up-regulation
TKL_MLK_ZAK_MAP3K20_ST	O96017	CHEK2	Q9NYL2	MAP3K20	S505	Q510H	510	Missense	distal	5	no	3.271	3.046	EPSD	COSMIC	2.674	Down-regulation
TKL_MLK_ZAK_MAP3K20_ST	O96017	CHEK2	Q9NYL2	MAP3K20	S516	R519Q	519	Missense	distal	3	no	2.827	2.465	EPSD	COSMIC	2.674	Loss
TKL_MLK_ZAK_MAP3K20_ST	O96017	CHEK2	Q9NYL2	MAP3K20	S516	R523P	523	Missense	distal	7	no	2.827	2.582	EPSD	COSMIC	2.674	Loss
TKL_MLK_ZAK_MAP3K20_ST	O96017	CHEK2	Q9NYL2	MAP3K20	S516	R519G	519	Missense	distal	3	no	2.827	3.084	EPSD	COSMIC	2.674	Up-regulation
TKL_MLK_ZAK_MAP3K20_ST	O96017	CHEK2	Q9NYL2	MAP3K20	S516	R523H	523	Missense	distal	7	no	2.827	2.695	EPSD	COSMIC	2.674	Down-regulation
TKL_MLK_ZAK_MAP3K20_ST	O96017	CHEK2	Q9NYL2	MAP3K20	S516	Q510H	510	Missense	distal	-6	no	2.827	2.674	EPSD	COSMIC	2.674	Down-regulation
TKL_MLK_ZAK_MAP3K20_ST	O96017	CHEK2	Q9NYL2	MAP3K20	S518	R519Q	519	Missense	proximal	1	no	3.168	3.178	EPSD	COSMIC	2.674	Up-regulation
TKL_MLK_ZAK_MAP3K20_ST	O96017	CHEK2	Q9NYL2	MAP3K20	S518	R523P	523	Missense	distal	5	no	3.168	2.989	EPSD	COSMIC	2.674	Down-regulation
TKL_MLK_ZAK_MAP3K20_ST	O96017	CHEK2	Q9NYL2	MAP3K20	S518	R519G	519	Missense	proximal	1	no	3.168	3.207	EPSD	COSMIC	2.674	Up-regulation
TKL_MLK_ZAK_MAP3K20_ST	O96017	CHEK2	Q9NYL2	MAP3K20	S518	R523H	523	Missense	distal	5	no	3.168	2.804	EPSD	COSMIC	2.674	Down-regulation
TKL_MLK_ZAK_MAP3K20_ST	O96017	CHEK2	Q9NYL2	MAP3K20	S518	E524K	524	Missense	distal	6	no	3.168	3.202	EPSD	COSMIC	2.674	Up-regulation
CAMK_CAMKL_NuaK_NUAK1_ST	P38936	CDKN1A	O60285	NUAK1	T97	G90R	90	Missense	distal	-7	no	4.897	5.124	EPSD	COSMIC	4.034	Up-regulation
CAMK_CAMKL_NuaK_NUAK1_ST	P38936	CDKN1A	O60285	NUAK1	T97	T97I	97	Missense	central	0	yes	4.897	0.000	EPSD	COSMIC	4.034	Loss
CAMK_CAMKL_NuaK_NUAK1_ST	P38936	CDKN1A	O60285	NUAK1	S98	T97I	97	Missense	proximal	-1	no	4.313	4.195	EPSD	COSMIC	4.034	Down-regulation
CAMK_CAMKL_NuaK_NUAK1_ST	P38936	CDKN1A	O60285	NUAK1	S130	E125Q	125	Missense	distal	-5	no	4.669	4.654	EPSD	COSMIC	4.034	Down-regulation
CAMK_CAMKL_NuaK_NUAK1_ST	P38936	CDKN1A	O60285	NUAK1	S130	S137T	137	Missense	distal	7	no	4.669	4.659	EPSD	COSMIC	4.034	Down-regulation
CAMK_CAMKL_NuaK_NUAK1_ST	P38936	CDKN1A	O60285	NUAK1	S137	R143W	143	Missense	distal	6	no	5.630	5.636	EPSD	COSMIC;GDSC;CCLE	4.034	Up-regulation
CAMK_CAMKL_NuaK_NUAK1_ST	P38936	CDKN1A	O60285	NUAK1	S137	Q138E	138	Missense	proximal	1	no	5.630	5.602	EPSD	COSMIC	4.034	Down-regulation
CAMK_CAMKL_NuaK_NUAK1_ST	P38936	CDKN1A	O60285	NUAK1	S137	G139C	139	Missense	proximal	2	no	5.630	5.413	EPSD	COSMIC	4.034	Down-regulation
CAMK_CAMKL_NuaK_NUAK1_ST	P38936	CDKN1A	O60285	NUAK1	S146	T145S	145	Missense	proximal	-1	no	5.858	5.555	PhosphoSitePlus	COSMIC	4.034	Down-regulation
CAMK_CAMKL_NuaK_NUAK1_ST	P38936	CDKN1A	O60285	NUAK1	S146	D149N	149	Missense	distal	3	no	5.858	5.840	PhosphoSitePlus	COSMIC	4.034	Down-regulation
CAMK_CAMKL_NuaK_NUAK1_ST	P38936	CDKN1A	O60285	NUAK1	S146	R143W	143	Missense	distal	-3	no	5.858	3.569	PhosphoSitePlus	COSMIC;GDSC;CCLE	4.034	Loss
CAMK_CAMKL_NuaK_NUAK1_ST	P38936	CDKN1A	O60285	NUAK1	S146	G139C	139	Missense	distal	-7	no	5.858	5.745	PhosphoSitePlus	COSMIC	4.034	Down-regulation
CAMK_CAMKL_NuaK_NUAK1_ST	P38936	CDKN1A	O60285	NUAK1	S153	R156W	156	Missense	distal	3	no	5.516	5.525	EPSD	COSMIC;GDSC;CCLE	4.034	Up-regulation
CAMK_CAMKL_NuaK_NUAK1_ST	P38936	CDKN1A	O60285	NUAK1	S153	I158M	158	Missense	distal	5	no	5.516	5.089	EPSD	COSMIC	4.034	Down-regulation
CAMK_CAMKL_NuaK_NUAK1_ST	P38936	CDKN1A	O60285	NUAK1	S153	D149N	149	Missense	distal	-4	no	5.516	5.555	EPSD	COSMIC	4.034	Up-regulation
CAMK_CAMKL_NuaK_NUAK1_ST	P38936	CDKN1A	O60285	NUAK1	S153	R155C	155	Missense	proximal	2	no	5.516	5.410	EPSD	COSMIC	4.034	Down-regulation
CAMK_CAMKL_NuaK_NUAK1_ST	P10636	MAPT	O60285	NUAK1	S214	E210Q	210	Missense	distal	-4	no	5.065	4.874	EPSD	COSMIC	4.034	Down-regulation
CAMK_CAMKL_NuaK_NUAK1_ST	P10636	MAPT	O60285	NUAK1	S214	G207E	207	Missense	distal	-7	no	5.065	5.025	EPSD	COSMIC	4.034	Down-regulation
CAMK_CAMKL_NuaK_NUAK1_ST	P10636	MAPT	O60285	NUAK1	S228	S227N	227	Missense	proximal	-1	no	3.770	4.162	EPSD	COSMIC	4.034	Gain
CAMK_CAMKL_NuaK_NUAK1_ST	P10636	MAPT	O60285	NUAK1	S228	E226K	226	Missense	proximal	-2	no	3.770	4.035	EPSD	COSMIC	4.034	Gain
CAMK_CAMKL_NuaK_NUAK1_ST	P10636	MAPT	O60285	NUAK1	S228	S227G	227	Missense	proximal	-1	no	3.770	4.362	EPSD	COSMIC	4.034	Gain
CAMK_CAMKL_NuaK_NUAK1_ST	P10636	MAPT	O60285	NUAK1	S369	R370W	370	Missense	proximal	1	no	4.000	4.064	EPSD	COSMIC	4.034	Gain
CAMK_CAMKL_NuaK_NUAK1_ST	P10636	MAPT	O60285	NUAK1	S382	G385V	385	Missense	distal	3	no	4.317	4.288	EPSD	COSMIC	4.034	Down-regulation
CAMK_CAMKL_NuaK_NUAK1_ST	P10636	MAPT	O60285	NUAK1	S382	T386I	386	Missense	distal	4	no	4.317	4.559	EPSD	COSMIC	4.034	Up-regulation
CAMK_CAMKL_NuaK_NUAK1_ST	P10636	MAPT	O60285	NUAK1	S382	R377W	377	Missense	distal	-5	no	4.317	4.299	EPSD	COSMIC	4.034	Down-regulation
CAMK_CAMKL_NuaK_NUAK1_ST	P10636	MAPT	O60285	NUAK1	S382	D389N	389	Missense	distal	7	no	4.317	4.362	EPSD	COSMIC;GDSC;CCLE	4.034	Up-regulation
CAMK_CAMKL_NuaK_NUAK1_ST	P10636	MAPT	O60285	NUAK1	S388	G385V	385	Missense	distal	-3	no	5.031	4.112	EPSD	COSMIC	4.034	Down-regulation
CAMK_CAMKL_NuaK_NUAK1_ST	P10636	MAPT	O60285	NUAK1	S388	T386I	386	Missense	proximal	-2	no	5.031	5.423	EPSD	COSMIC	4.034	Up-regulation
CAMK_CAMKL_NuaK_NUAK1_ST	P10636	MAPT	O60285	NUAK1	S388	D389N	389	Missense	proximal	1	no	5.031	5.001	EPSD	COSMIC;GDSC;CCLE	4.034	Down-regulation
CAMK_CAMKL_NuaK_NUAK1_ST	P10636	MAPT	O60285	NUAK1	S438	S443Y	443	Missense	distal	5	no	4.184	4.437	EPSD	COSMIC	4.034	Up-regulation
CAMK_CAMKL_NuaK_NUAK1_ST	P10636	MAPT	O60285	NUAK1	S451	S447P	447	Missense	distal	-4	no	4.528	4.400	EPSD	COSMIC	4.034	Down-regulation
CAMK_CAMKL_NuaK_NUAK1_ST	P10636	MAPT	O60285	NUAK1	S451	R448Q	448	Missense	distal	-3	no	4.528	2.312	EPSD	COSMIC	4.034	Loss
CAMK_CAMKL_NuaK_NUAK1_ST	P10636	MAPT	O60285	NUAK1	T470	T466M	466	Missense	distal	-4	no	4.777	4.947	EPSD	COSMIC;GDSC;CCLE	4.034	Up-regulation
CAMK_CAMKL_NuaK_NUAK1_ST	P10636	MAPT	O60285	NUAK1	T470	K467T	467	Missense	distal	-3	no	4.777	2.944	EPSD	COSMIC	4.034	Loss
CAMK_CAMKL_NuaK_NUAK1_ST	P10636	MAPT	O60285	NUAK1	T470	P477L	477	Missense	distal	7	no	4.777	4.648	EPSD	COSMIC	4.034	Down-regulation
CAMK_CAMKL_NuaK_NUAK1_ST	P10636	MAPT	O60285	NUAK1	T470	P477S	477	Missense	distal	7	no	4.777	4.892	EPSD	COSMIC	4.034	Up-regulation
CAMK_CAMKL_NuaK_NUAK1_ST	P10636	MAPT	O60285	NUAK1	S502	P506S	506	Missense	distal	4	no	4.101	3.653	EPSD	COSMIC	4.034	Loss
CAMK_CAMKL_NuaK_NUAK1_ST	P10636	MAPT	O60285	NUAK1	S502	A495T	495	Missense	distal	-7	no	4.101	4.171	EPSD	COSMIC	4.034	Up-regulation
CAMK_CAMKL_NuaK_NUAK1_ST	P10636	MAPT	O60285	NUAK1	S502	G509V	509	Missense	distal	7	no	4.101	3.884	EPSD	COSMIC	4.034	Loss
CAMK_CAMKL_NuaK_NUAK1_ST	P10636	MAPT	O60285	NUAK1	S502	P506L	506	Missense	distal	4	no	4.101	5.174	EPSD	COSMIC	4.034	Up-regulation
CAMK_CAMKL_NuaK_NUAK1_ST	P10636	MAPT	O60285	NUAK1	S531	R526H	526	Missense	distal	-5	no	4.912	4.842	EPSD	COSMIC	4.034	Down-regulation
CAMK_CAMKL_NuaK_NUAK1_ST	P10636	MAPT	O60285	NUAK1	S531	R528S	528	Missense	distal	-3	no	4.912	2.884	EPSD	COSMIC	4.034	Loss
CAMK_CAMKL_NuaK_NUAK1_ST	P10636	MAPT	O60285	NUAK1	S531	P530S	530	Missense	proximal	-1	no	4.912	4.752	EPSD	COSMIC	4.034	Down-regulation
CAMK_CAMKL_NuaK_NUAK1_ST	P10636	MAPT	O60285	NUAK1	S531	P536H	536	Missense	distal	5	no	4.912	5.146	EPSD	COSMIC	4.034	Up-regulation
CAMK_CAMKL_NuaK_NUAK1_ST	P10636	MAPT	O60285	NUAK1	S531	P535Q	535	Missense	distal	4	no	4.912	4.660	EPSD	COSMIC	4.034	Down-regulation
CAMK_CAMKL_NuaK_NUAK1_ST	P10636	MAPT	O60285	NUAK1	S579	T580N	580	Missense	proximal	1	no	9.984	9.969	EPSD	COSMIC	4.034	Down-regulation
CAMK_CAMKL_NuaK_NUAK1_ST	P10636	MAPT	O60285	NUAK1	S579	G578S	578	Missense	proximal	-1	no	9.984	9.393	EPSD	COSMIC	4.034	Down-regulation
CAMK_CAMKL_NuaK_NUAK1_ST	P10636	MAPT	O60285	NUAK1	S610	N613D	613	Missense	distal	3	no	6.530	6.548	EPSD	COSMIC	4.034	Up-regulation
CAMK_CAMKL_NuaK_NUAK1_ST	P10636	MAPT	O60285	NUAK1	S610	C608W	608	Missense	proximal	-2	no	6.530	6.490	EPSD	COSMIC	4.034	Down-regulation
CAMK_CAMKL_NuaK_NUAK1_ST	P10636	MAPT	O60285	NUAK1	S610	S610L	610	Missense	central	0	yes	6.530	0.000	EPSD	COSMIC	4.034	Loss
CAMK_CAMKL_NuaK_NUAK1_ST	P10636	MAPT	O60285	NUAK1	S641	H647Y	647	Missense	distal	6	no	5.629	5.620	EPSD	COSMIC	4.034	Down-regulation
CAMK_CAMKL_NuaK_NUAK1_ST	P10636	MAPT	O60285	NUAK1	S669	S673F	673	Missense	distal	4	no	3.432	4.897	EPSD	COSMIC	4.034	Gain
CAMK_CAMKL_NuaK_NUAK1_ST	P10636	MAPT	O60285	NUAK1	S673	V680I	680	Missense	distal	7	no	8.887	9.162	EPSD	COSMIC	4.034	Up-regulation
CAMK_CAMKL_NuaK_NUAK1_ST	P10636	MAPT	O60285	NUAK1	S673	S669L	669	Missense	distal	-4	no	8.887	8.706	EPSD	COSMIC	4.034	Down-regulation
CAMK_CAMKL_NuaK_NUAK1_ST	P10636	MAPT	O60285	NUAK1	S673	R666K	666	Missense	distal	-7	no	8.887	8.407	EPSD	COSMIC	4.034	Down-regulation
CAMK_CAMKL_NuaK_NUAK1_ST	P10636	MAPT	O60285	NUAK1	S673	S673F	673	Missense	central	0	yes	8.887	0.000	EPSD	COSMIC	4.034	Loss
CAMK_CAMKL_NuaK_NUAK1_ST	P10636	MAPT	O60285	NUAK1	S673	K670N	670	Missense	distal	-3	no	8.887	7.160	EPSD	COSMIC	4.034	Down-regulation
CAMK_CAMKL_NuaK_NUAK1_ST	P10636	MAPT	O60285	NUAK1	S673	L674Q	674	Missense	proximal	1	no	8.887	8.920	EPSD	COSMIC	4.034	Up-regulation
CAMK_CAMKL_NuaK_NUAK1_ST	O14974	PPP1R12A	O60285	NUAK1	S445	A448V	448	Missense	distal	3	no	9.000	8.967	EPSD;PhosphoSitePlus	COSMIC	4.034	Down-regulation
CAMK_CAMKL_NuaK_NUAK1_ST	O14974	PPP1R12A	O60285	NUAK1	S472	R469C	469	Missense	distal	-3	no	9.804	8.126	PhosphoSitePlus;EPSD	COSMIC	4.034	Down-regulation
CAMK_CAMKL_NuaK_NUAK1_ST	O14974	PPP1R12A	O60285	NUAK1	S472	A465S	465	Missense	distal	-7	no	9.804	9.890	PhosphoSitePlus;EPSD	COSMIC	4.034	Up-regulation
CAMK_CAMKL_NuaK_NUAK1_ST	O14974	PPP1R12A	O60285	NUAK1	S472	S478C	478	Missense	distal	6	no	9.804	9.780	PhosphoSitePlus;EPSD	COSMIC	4.034	Down-regulation
CAMK_CAMKL_NuaK_NUAK1_ST	O14974	PPP1R12A	O60285	NUAK1	S554	S554F	554	Missense	central	0	yes	5.509	0.000	EPSD	COSMIC	4.034	Loss
CAMK_CAMKL_NuaK_NUAK1_ST	O14974	PPP1R12A	O60285	NUAK1	S554	S554C	554	Missense	central	0	yes	5.509	0.000	EPSD	COSMIC	4.034	Loss
CAMK_CAMKL_NuaK_NUAK1_ST	O14974	PPP1R12A	O60285	NUAK1	S572	T575A	575	Missense	distal	3	no	4.106	4.133	EPSD	COSMIC	4.034	Up-regulation
CAMK_CAMKL_NuaK_NUAK1_ST	O14974	PPP1R12A	O60285	NUAK1	S572	T573A	573	Missense	proximal	1	no	4.106	4.179	EPSD	COSMIC	4.034	Up-regulation
CAMK_CAMKL_NuaK_NUAK1_ST	O14974	PPP1R12A	O60285	NUAK1	S602	S601F	601	Missense	proximal	-1	no	3.569	4.039	EPSD	COSMIC	4.034	Gain
CAMK_CAMKL_NuaK_NUAK1_ST	O14974	PPP1R12A	O60285	NUAK1	S668	R663I	663	Missense	distal	-5	no	4.184	4.236	EPSD	COSMIC	4.034	Up-regulation
CAMK_CAMKL_NuaK_NUAK1_ST	O14974	PPP1R12A	O60285	NUAK1	S716	R718Q	718	Missense	proximal	2	no	4.110	4.041	EPSD	COSMIC	4.034	Down-regulation
CAMK_CAMKL_NuaK_NUAK1_ST	O14974	PPP1R12A	O60285	NUAK1	S921	S922P	922	Missense	proximal	1	no	4.692	4.698	EPSD	COSMIC	4.034	Up-regulation
CAMK_CAMKL_NuaK_NUAK1_ST	O14974	PPP1R12A	O60285	NUAK1	S929	S922P	922	Missense	distal	-7	no	5.157	5.003	EPSD	COSMIC	4.034	Down-regulation
CAMK_CAMKL_NuaK_NUAK1_ST	O14974	PPP1R12A	O60285	NUAK1	S929	D931N	931	Missense	proximal	2	no	5.157	5.181	EPSD	COSMIC	4.034	Up-regulation
CAMK_CAMKL_NuaK_NUAK1_ST	P55212	CASP6	O60285	NUAK1	S3	S5L	5	Missense	proximal	2	no	4.590	4.186	EPSD	COSMIC	4.034	Down-regulation
CAMK_CAMKL_NuaK_NUAK1_ST	P55212	CASP6	O60285	NUAK1	S79	D80Y	80	Missense	proximal	1	no	4.402	4.399	EPSD	COSMIC	4.034	Down-regulation
CAMK_CAMKL_NuaK_NUAK1_ST	P55212	CASP6	O60285	NUAK1	S79	R76H	76	Missense	distal	-3	no	4.402	1.762	EPSD	COSMIC;GDSC;CCLE	4.034	Loss
CAMK_CAMKL_NuaK_NUAK1_ST	P55212	CASP6	O60285	NUAK1	S257	R259S	259	Missense	proximal	2	no	9.653	9.794	PhosphoSitePlus	COSMIC	4.034	Up-regulation
CAMK_CAMKL_NuaK_NUAK1_ST	P04637	TP53	O60285	NUAK1	S6	E3G	3	Missense	distal	-3	no	3.480	4.405	EPSD	COSMIC	4.034	Gain
CAMK_CAMKL_NuaK_NUAK1_ST	P04637	TP53	O60285	NUAK1	S15	E11Q	11	Missense	distal	-4	no	7.071	6.879	EPSD;PhosphoSitePlus	COSMIC;GDSC;CCLE	4.034	Down-regulation
CAMK_CAMKL_NuaK_NUAK1_ST	P04637	TP53	O60285	NUAK1	S15	S20L	20	Missense	distal	5	no	7.071	7.476	EPSD;PhosphoSitePlus	COSMIC	4.034	Up-regulation
CAMK_CAMKL_NuaK_NUAK1_ST	P04637	TP53	O60285	NUAK1	S15	Q16L	16	Missense	proximal	1	no	7.071	7.037	EPSD;PhosphoSitePlus	COSMIC;GDSC;CCLE	4.034	Down-regulation
CAMK_CAMKL_NuaK_NUAK1_ST	P04637	TP53	O60285	NUAK1	S15	P13S	13	Missense	proximal	-2	no	7.071	6.969	EPSD;PhosphoSitePlus	COSMIC	4.034	Down-regulation
CAMK_CAMKL_NuaK_NUAK1_ST	P04637	TP53	O60285	NUAK1	S15	E17K	17	Missense	proximal	2	no	7.071	6.722	EPSD;PhosphoSitePlus	COSMIC	4.034	Down-regulation
CAMK_CAMKL_NuaK_NUAK1_ST	P04637	TP53	O60285	NUAK1	S15	V10I	10	Missense	distal	-5	no	7.071	7.012	EPSD;PhosphoSitePlus	COSMIC	4.034	Down-regulation
CAMK_CAMKL_NuaK_NUAK1_ST	P04637	TP53	O60285	NUAK1	S15	P8L	8	Missense	distal	-7	no	7.071	7.085	EPSD;PhosphoSitePlus	COSMIC	4.034	Up-regulation
CAMK_CAMKL_NuaK_NUAK1_ST	P04637	TP53	O60285	NUAK1	S15	P8S	8	Missense	distal	-7	no	7.071	7.224	EPSD;PhosphoSitePlus	COSMIC	4.034	Up-regulation
CAMK_CAMKL_NuaK_NUAK1_ST	P04637	TP53	O60285	NUAK1	S15	P13L	13	Missense	proximal	-2	no	7.071	6.110	EPSD;PhosphoSitePlus	COSMIC	4.034	Down-regulation
CAMK_CAMKL_NuaK_NUAK1_ST	P04637	TP53	O60285	NUAK1	S15	V10G	10	Missense	distal	-5	no	7.071	6.988	EPSD;PhosphoSitePlus	COSMIC	4.034	Down-regulation
CAMK_CAMKL_NuaK_NUAK1_ST	P04637	TP53	O60285	NUAK1	S15	T18A	18	Missense	distal	3	no	7.071	7.097	EPSD;PhosphoSitePlus	COSMIC	4.034	Up-regulation
CAMK_CAMKL_NuaK_NUAK1_ST	P04637	TP53	O60285	NUAK1	S15	F19S	19	Missense	distal	4	no	7.071	5.605	EPSD;PhosphoSitePlus	COSMIC	4.034	Down-regulation
CAMK_CAMKL_NuaK_NUAK1_ST	P04637	TP53	O60285	NUAK1	S15	E17V	17	Missense	proximal	2	no	7.071	6.754	EPSD;PhosphoSitePlus	COSMIC	4.034	Down-regulation
CAMK_CAMKL_NuaK_NUAK1_ST	P04637	TP53	O60285	NUAK1	S15	S9G	9	Missense	distal	-6	no	7.071	7.170	EPSD;PhosphoSitePlus	COSMIC	4.034	Up-regulation
CAMK_CAMKL_NuaK_NUAK1_ST	P04637	TP53	O60285	NUAK1	S15	T18I	18	Missense	distal	3	no	7.071	7.020	EPSD;PhosphoSitePlus	COSMIC	4.034	Down-regulation
CAMK_CAMKL_NuaK_NUAK1_ST	P04637	TP53	O60285	NUAK1	S15	T18K	18	Missense	distal	3	no	7.071	7.128	EPSD;PhosphoSitePlus	COSMIC	4.034	Up-regulation
CAMK_CAMKL_NuaK_NUAK1_ST	P04637	TP53	O60285	NUAK1	S15	T18R	18	Missense	distal	3	no	7.071	7.063	EPSD;PhosphoSitePlus	COSMIC	4.034	Down-regulation
CAMK_CAMKL_NuaK_NUAK1_ST	P04637	TP53	O60285	NUAK1	S15	S15I	15	Missense	central	0	yes	7.071	0.000	EPSD;PhosphoSitePlus	COSMIC	4.034	Loss
CAMK_CAMKL_NuaK_NUAK1_ST	P04637	TP53	O60285	NUAK1	S183	G187V	187	Missense	distal	4	no	3.021	4.281	EPSD	COSMIC	4.034	Gain
CAMK_CAMKL_NuaK_NUAK1_ST	P04637	TP53	O60285	NUAK1	S376	H380Y	380	Missense	distal	4	no	3.598	4.223	EPSD	COSMIC	4.034	Gain
CAMK_CAMKL_NuaK_NUAK1_ST	P04637	TP53	O60285	NUAK1	S376	G374S	374	Missense	proximal	-2	no	3.598	4.339	EPSD	COSMIC	4.034	Gain
CAMK_CAMKL_NuaK_NUAK1_ST	P04637	TP53	O60285	NUAK1	S392	P390L	390	Missense	proximal	-2	no	6.382	5.421	PhosphoSitePlus;EPSD	COSMIC	4.034	Down-regulation
CAMK_CAMKL_NuaK_NUAK1_ST	P04637	TP53	O60285	NUAK1	S392	S392P	392	Missense	central	0	yes	6.382	0.000	PhosphoSitePlus;EPSD	COSMIC	4.034	Loss
CAMK_CAMKL_NuaK_NUAK1_ST	P04637	TP53	O60285	NUAK1	S392	K386N	386	Missense	distal	-6	no	6.382	6.404	PhosphoSitePlus;EPSD	COSMIC	4.034	Up-regulation
CAMK_CAMKL_NuaK_NUAK1_ST	P04637	TP53	O60285	NUAK1	S392	G389E	389	Missense	distal	-3	no	6.382	5.457	PhosphoSitePlus;EPSD	COSMIC	4.034	Down-regulation
CAMK_CAMKL_NuaK_NUAK1_ST	P04637	TP53	O60285	NUAK1	S392	S392L	392	Missense	central	0	yes	6.382	0.000	PhosphoSitePlus;EPSD	COSMIC	4.034	Loss
CAMK_CAMKL_NuaK_NUAK1_ST	P04637	TP53	O60285	NUAK1	S392	D391N	391	Missense	proximal	-1	no	6.382	6.273	PhosphoSitePlus;EPSD	COSMIC	4.034	Down-regulation
CAMK_CAMKL_NuaK_NUAK1_ST	P04637	TP53	O60285	NUAK1	S392	D391Y	391	Missense	proximal	-1	no	6.382	6.052	PhosphoSitePlus;EPSD	COSMIC	4.034	Down-regulation
CAMK_CAMKL_NuaK_NUAK1_ST	P04637	TP53	O60285	NUAK1	S392	G389V	389	Missense	distal	-3	no	6.382	5.462	PhosphoSitePlus;EPSD	COSMIC	4.034	Down-regulation
CAMK_CAMKL_NuaK_NUAK1_ST	O95835	LATS1	O60285	NUAK1	S42	N40S	40	Missense	proximal	-2	no	3.603	4.282	EPSD	COSMIC	4.034	Gain
CAMK_CAMKL_NuaK_NUAK1_ST	O95835	LATS1	O60285	NUAK1	S204	S204G	204	Missense	central	0	yes	4.356	0.000	EPSD	COSMIC	4.034	Loss
CAMK_CAMKL_NuaK_NUAK1_ST	O95835	LATS1	O60285	NUAK1	S204	Y200S	200	Missense	distal	-4	no	4.356	4.535	EPSD	COSMIC	4.034	Up-regulation
CAMK_CAMKL_NuaK_NUAK1_ST	O95835	LATS1	O60285	NUAK1	S204	A199T	199	Missense	distal	-5	no	4.356	4.302	EPSD	COSMIC	4.034	Down-regulation
CAMK_CAMKL_NuaK_NUAK1_ST	O95835	LATS1	O60285	NUAK1	S204	S202F	202	Missense	proximal	-2	no	4.356	3.728	EPSD	COSMIC	4.034	Loss
CAMK_CAMKL_NuaK_NUAK1_ST	O95835	LATS1	O60285	NUAK1	S387	P386L	386	Missense	proximal	-1	no	4.540	4.897	EPSD	COSMIC	4.034	Up-regulation
CAMK_CAMKL_NuaK_NUAK1_ST	O95835	LATS1	O60285	NUAK1	S387	S394Y	394	Missense	distal	7	no	4.540	4.448	EPSD	COSMIC	4.034	Down-regulation
CAMK_CAMKL_NuaK_NUAK1_ST	O95835	LATS1	O60285	NUAK1	S408	G403E	403	Missense	distal	-5	no	4.127	4.078	EPSD	COSMIC	4.034	Down-regulation
CAMK_CAMKL_NuaK_NUAK1_ST	O95835	LATS1	O60285	NUAK1	S464	N471K	471	Missense	distal	7	no	9.586	9.489	PhosphoSitePlus	COSMIC	4.034	Down-regulation
CAMK_CAMKL_NuaK_NUAK1_ST	O95835	LATS1	O60285	NUAK1	S596	N599I	599	Missense	distal	3	no	5.604	5.552	EPSD	COSMIC	4.034	Down-regulation
CAMK_CAMKL_NuaK_NUAK1_ST	O95835	LATS1	O60285	NUAK1	S596	S593R	593	Missense	distal	-3	no	5.604	7.632	EPSD	COSMIC	4.034	Up-regulation
CAMK_CAMKL_NuaK_NUAK1_ST	O95835	LATS1	O60285	NUAK1	S596	E592K	592	Missense	distal	-4	no	5.604	5.415	EPSD	COSMIC	4.034	Down-regulation
CAMK_CAMKL_NuaK_NUAK1_ST	O95835	LATS1	O60285	NUAK1	S596	E598K	598	Missense	proximal	2	no	5.604	5.255	EPSD	COSMIC	4.034	Down-regulation
CAMK_CAMKL_NuaK_NUAK1_ST	O95835	LATS1	O60285	NUAK1	S596	K595N	595	Missense	proximal	-1	no	5.604	5.796	EPSD	COSMIC	4.034	Up-regulation
CAMK_CAMKL_NuaK_NUAK1_ST	O95835	LATS1	O60285	NUAK1	S596	N599H	599	Missense	distal	3	no	5.604	5.615	EPSD	COSMIC	4.034	Up-regulation
CAMK_CAMKL_NuaK_NUAK1_ST	O95835	LATS1	O60285	NUAK1	S596	S593C	593	Missense	distal	-3	no	5.604	5.954	EPSD	COSMIC	4.034	Up-regulation
CAMK_CAMKL_NuaK_NUAK1_ST	O95835	LATS1	O60285	NUAK1	S633	F639L	639	Missense	distal	6	no	4.312	4.301	EPSD	COSMIC	4.034	Down-regulation
CAMK_CAMKL_NuaK_NUAK1_ST	O95835	LATS1	O60285	NUAK1	S633	S629P	629	Missense	distal	-4	no	4.312	4.184	EPSD	COSMIC	4.034	Down-regulation
CAMK_CAMKL_NuaK_NUAK1_ST	O95835	LATS1	O60285	NUAK1	S633	R627M	627	Missense	distal	-6	no	4.312	4.467	EPSD	COSMIC	4.034	Up-regulation
CAMK_CAMKL_NuaK_NUAK1_ST	O95835	LATS1	O60285	NUAK1	S633	Q632E	632	Missense	proximal	-1	no	4.312	4.624	EPSD	COSMIC	4.034	Up-regulation
CAMK_CAMKL_NuaK_NUAK1_ST	O95835	LATS1	O60285	NUAK1	S872	E878D	878	Missense	distal	6	no	4.576	4.561	EPSD	COSMIC	4.034	Down-regulation
CAMK_CAMKL_NuaK_NUAK1_ST	O95835	LATS1	O60285	NUAK1	S872	S876R	876	Missense	distal	4	no	4.576	4.832	EPSD	COSMIC	4.034	Up-regulation
Other_ULK_ULK_ULK2_ST	O15027	SEC16A	Q8IYT8	ULK2	S122	P128L	128	Missense	distal	6	no	3.942	3.944	EPSD	COSMIC	3.097	Up-regulation
Other_ULK_ULK_ULK2_ST	O15027	SEC16A	Q8IYT8	ULK2	S136	P143L	143	Missense	distal	7	no	4.720	4.753	EPSD	COSMIC	3.097	Up-regulation
Other_ULK_ULK_ULK2_ST	O15027	SEC16A	Q8IYT8	ULK2	S179	P183L	183	Missense	distal	4	no	4.491	4.458	EPSD	COSMIC	3.097	Down-regulation
Other_ULK_ULK_ULK2_ST	O15027	SEC16A	Q8IYT8	ULK2	T337	T334A	334	Missense	distal	-3	no	3.733	3.728	EPSD	COSMIC	3.097	Down-regulation
Other_ULK_ULK_ULK2_ST	O15027	SEC16A	Q8IYT8	ULK2	S346	G353R	353	Missense	distal	7	no	3.321	3.462	EPSD	COSMIC	3.097	Up-regulation
Other_ULK_ULK_ULK2_ST	O15027	SEC16A	Q8IYT8	ULK2	S346	S351N	351	Missense	distal	5	no	3.321	3.344	EPSD	COSMIC	3.097	Up-regulation
Other_ULK_ULK_ULK2_ST	O15027	SEC16A	Q8IYT8	ULK2	S356	P361L	361	Missense	distal	5	no	3.295	3.248	EPSD	COSMIC	3.097	Down-regulation
Other_ULK_ULK_ULK2_ST	O15027	SEC16A	Q8IYT8	ULK2	S356	L355R	355	Missense	proximal	-1	no	3.295	2.875	EPSD	COSMIC;GDSC	3.097	Loss
Other_ULK_ULK_ULK2_ST	O15027	SEC16A	Q8IYT8	ULK2	S356	G353R	353	Missense	distal	-3	no	3.295	3.973	EPSD	COSMIC	3.097	Up-regulation
Other_ULK_ULK_ULK2_ST	O15027	SEC16A	Q8IYT8	ULK2	S356	R354T	354	Missense	proximal	-2	no	3.295	3.321	EPSD	COSMIC	3.097	Up-regulation
Other_ULK_ULK_ULK2_ST	O15027	SEC16A	Q8IYT8	ULK2	S356	S351N	351	Missense	distal	-5	no	3.295	3.253	EPSD	COSMIC	3.097	Down-regulation
Other_ULK_ULK_ULK2_ST	O15027	SEC16A	Q8IYT8	ULK2	S358	P361L	361	Missense	distal	3	no	3.930	3.878	EPSD	COSMIC	3.097	Down-regulation
Other_ULK_ULK_ULK2_ST	O15027	SEC16A	Q8IYT8	ULK2	S358	L355R	355	Missense	distal	-3	no	3.930	4.394	EPSD	COSMIC;GDSC	3.097	Up-regulation
Other_ULK_ULK_ULK2_ST	O15027	SEC16A	Q8IYT8	ULK2	S358	G353R	353	Missense	distal	-5	no	3.930	3.919	EPSD	COSMIC	3.097	Down-regulation
Other_ULK_ULK_ULK2_ST	O15027	SEC16A	Q8IYT8	ULK2	S358	R354T	354	Missense	distal	-4	no	3.930	4.082	EPSD	COSMIC	3.097	Up-regulation
Other_ULK_ULK_ULK2_ST	O15027	SEC16A	Q8IYT8	ULK2	S358	S351N	351	Missense	distal	-7	no	3.930	3.989	EPSD	COSMIC	3.097	Up-regulation
Other_ULK_ULK_ULK2_ST	O15027	SEC16A	Q8IYT8	ULK2	S381	G382D	382	Missense	proximal	1	no	3.545	3.647	EPSD	COSMIC	3.097	Up-regulation
Other_ULK_ULK_ULK2_ST	O15027	SEC16A	Q8IYT8	ULK2	S381	P376L	376	Missense	distal	-5	no	3.545	3.536	EPSD	COSMIC	3.097	Down-regulation
Other_ULK_ULK_ULK2_ST	O15027	SEC16A	Q8IYT8	ULK2	S381	F385L	385	Missense	distal	4	no	3.545	3.484	EPSD	COSMIC	3.097	Down-regulation
Other_ULK_ULK_ULK2_ST	O15027	SEC16A	Q8IYT8	ULK2	S381	S383I	383	Missense	proximal	2	no	3.545	3.447	EPSD	COSMIC	3.097	Down-regulation
Other_ULK_ULK_ULK2_ST	O15027	SEC16A	Q8IYT8	ULK2	S391	G395D	395	Missense	distal	4	no	3.669	3.567	EPSD	COSMIC;GDSC;CCLE	3.097	Down-regulation
Other_ULK_ULK_ULK2_ST	O15027	SEC16A	Q8IYT8	ULK2	S391	T397K	397	Missense	distal	6	no	3.669	3.668	EPSD	COSMIC	3.097	Down-regulation
Other_ULK_ULK_ULK2_ST	O15027	SEC16A	Q8IYT8	ULK2	S391	V393I	393	Missense	proximal	2	no	3.669	3.269	EPSD	COSMIC	3.097	Down-regulation
Other_ULK_ULK_ULK2_ST	O15027	SEC16A	Q8IYT8	ULK2	S391	F385L	385	Missense	distal	-6	no	3.669	3.686	EPSD	COSMIC	3.097	Up-regulation
Other_ULK_ULK_ULK2_ST	O15027	SEC16A	Q8IYT8	ULK2	S432	S431N	431	Missense	proximal	-1	no	3.203	3.014	EPSD	COSMIC;CCLE	3.097	Loss
Other_ULK_ULK_ULK2_ST	O15027	SEC16A	Q8IYT8	ULK2	S432	E434K	434	Missense	proximal	2	no	3.203	3.016	EPSD	COSMIC	3.097	Loss
Other_ULK_ULK_ULK2_ST	O15027	SEC16A	Q8IYT8	ULK2	S432	P435L	435	Missense	distal	3	no	3.203	3.151	EPSD	COSMIC;CCLE	3.097	Down-regulation
Other_ULK_ULK_ULK2_ST	O15027	SEC16A	Q8IYT8	ULK2	S432	P435Q	435	Missense	distal	3	no	3.203	3.187	EPSD	COSMIC	3.097	Down-regulation
Other_ULK_ULK_ULK2_ST	O15027	SEC16A	Q8IYT8	ULK2	S531	A532V	532	Missense	proximal	1	no	2.539	3.590	EPSD	COSMIC	3.097	Gain
Other_ULK_ULK_ULK2_ST	O15027	SEC16A	Q8IYT8	ULK2	S551	L553P	553	Missense	proximal	2	no	2.786	3.225	EPSD	COSMIC	3.097	Gain
Other_ULK_ULK_ULK2_ST	O15027	SEC16A	Q8IYT8	ULK2	S596	A598V	598	Missense	proximal	2	no	4.084	4.370	EPSD	COSMIC;GDSC;CCLE	3.097	Up-regulation
Other_ULK_ULK_ULK2_ST	O15027	SEC16A	Q8IYT8	ULK2	S596	P600L	600	Missense	distal	4	no	4.084	4.051	EPSD	COSMIC	3.097	Down-regulation
Other_ULK_ULK_ULK2_ST	O15027	SEC16A	Q8IYT8	ULK2	S596	A599T	599	Missense	distal	3	no	4.084	3.980	EPSD	COSMIC	3.097	Down-regulation
Other_ULK_ULK_ULK2_ST	O15027	SEC16A	Q8IYT8	ULK2	S596	R593W	593	Missense	distal	-3	no	4.084	3.400	EPSD	COSMIC;GDSC;CCLE	3.097	Down-regulation
Other_ULK_ULK_ULK2_ST	O15027	SEC16A	Q8IYT8	ULK2	S596	P600Q	600	Missense	distal	4	no	4.084	4.122	EPSD	COSMIC	3.097	Up-regulation
Other_ULK_ULK_ULK2_ST	O15027	SEC16A	Q8IYT8	ULK2	S597	A598V	598	Missense	proximal	1	no	2.226	3.277	EPSD	COSMIC;GDSC;CCLE	3.097	Gain
Other_ULK_ULK_ULK2_ST	O15027	SEC16A	Q8IYT8	ULK2	S668	Q663P	663	Missense	distal	-5	no	8.682	8.563	EPSD	COSMIC	3.097	Down-regulation
Other_ULK_ULK_ULK2_ST	O15027	SEC16A	Q8IYT8	ULK2	S668	A662D	662	Missense	distal	-6	no	8.682	8.361	EPSD	COSMIC	3.097	Down-regulation
Other_ULK_ULK_ULK2_ST	O15027	SEC16A	Q8IYT8	ULK2	S668	S672L	672	Missense	distal	4	no	8.682	8.769	EPSD	COSMIC	3.097	Up-regulation
Other_ULK_ULK_ULK2_ST	O15027	SEC16A	Q8IYT8	ULK2	S668	F667L	667	Missense	proximal	-1	no	8.682	8.710	EPSD	COSMIC	3.097	Up-regulation
Other_ULK_ULK_ULK2_ST	O15027	SEC16A	Q8IYT8	ULK2	S771	R767H	767	Missense	distal	-4	no	3.216	3.304	EPSD	COSMIC	3.097	Up-regulation
Other_ULK_ULK_ULK2_ST	O15027	SEC16A	Q8IYT8	ULK2	S771	P774L	774	Missense	distal	3	no	3.216	3.164	EPSD	COSMIC	3.097	Down-regulation
Other_ULK_ULK_ULK2_ST	O15027	SEC16A	Q8IYT8	ULK2	S771	P774S	774	Missense	distal	3	no	3.216	3.117	EPSD	COSMIC	3.097	Down-regulation
Other_ULK_ULK_ULK2_ST	O15027	SEC16A	Q8IYT8	ULK2	S771	G775R	775	Missense	distal	4	no	3.216	3.282	EPSD	COSMIC	3.097	Up-regulation
Other_ULK_ULK_ULK2_ST	O15027	SEC16A	Q8IYT8	ULK2	S771	A769T	769	Missense	proximal	-2	no	3.216	3.245	EPSD	COSMIC	3.097	Up-regulation
Other_ULK_ULK_ULK2_ST	O15027	SEC16A	Q8IYT8	ULK2	S771	R767L	767	Missense	distal	-4	no	3.216	3.237	EPSD	COSMIC;GDSC;CCLE	3.097	Up-regulation
Other_ULK_ULK_ULK2_ST	O15027	SEC16A	Q8IYT8	ULK2	S771	R767C	767	Missense	distal	-4	no	3.216	3.274	EPSD	COSMIC	3.097	Up-regulation
Other_ULK_ULK_ULK2_ST	O15027	SEC16A	Q8IYT8	ULK2	S779	P774L	774	Missense	distal	-5	no	3.511	3.502	EPSD	COSMIC	3.097	Down-regulation
Other_ULK_ULK_ULK2_ST	O15027	SEC16A	Q8IYT8	ULK2	S779	P774S	774	Missense	distal	-5	no	3.511	3.597	EPSD	COSMIC	3.097	Up-regulation
Other_ULK_ULK_ULK2_ST	O15027	SEC16A	Q8IYT8	ULK2	S779	S783N	783	Missense	distal	4	no	3.511	3.637	EPSD	COSMIC	3.097	Up-regulation
Other_ULK_ULK_ULK2_ST	O15027	SEC16A	Q8IYT8	ULK2	S779	G775R	775	Missense	distal	-4	no	3.511	3.419	EPSD	COSMIC	3.097	Down-regulation
Other_ULK_ULK_ULK2_ST	O15027	SEC16A	Q8IYT8	ULK2	S785	A792V	792	Missense	distal	7	no	3.640	3.421	EPSD	COSMIC	3.097	Down-regulation
Other_ULK_ULK_ULK2_ST	O15027	SEC16A	Q8IYT8	ULK2	S785	S783N	783	Missense	proximal	-2	no	3.640	3.618	EPSD	COSMIC	3.097	Down-regulation
Other_ULK_ULK_ULK2_ST	O15027	SEC16A	Q8IYT8	ULK2	S806	N801S	801	Missense	distal	-5	no	3.369	3.411	EPSD	COSMIC	3.097	Up-regulation
Other_ULK_ULK_ULK2_ST	O15027	SEC16A	Q8IYT8	ULK2	S806	T812A	812	Missense	distal	6	no	3.369	3.375	EPSD	COSMIC	3.097	Up-regulation
Other_ULK_ULK_ULK2_ST	O15027	SEC16A	Q8IYT8	ULK2	T812	G814R	814	Missense	proximal	2	no	3.141	3.717	EPSD	COSMIC	3.097	Up-regulation
Other_ULK_ULK_ULK2_ST	O15027	SEC16A	Q8IYT8	ULK2	T812	T812A	812	Missense	central	0	yes	3.141	0.000	EPSD	COSMIC	3.097	Loss
Other_ULK_ULK_ULK2_ST	O15027	SEC16A	Q8IYT8	ULK2	T812	G814E	814	Missense	proximal	2	no	3.141	3.334	EPSD	COSMIC	3.097	Up-regulation
Other_ULK_ULK_ULK2_ST	O15027	SEC16A	Q8IYT8	ULK2	T812	T819A	819	Missense	distal	7	no	3.141	3.181	EPSD	COSMIC	3.097	Up-regulation
Other_ULK_ULK_ULK2_ST	O15027	SEC16A	Q8IYT8	ULK2	T819	G814R	814	Missense	distal	-5	no	3.672	3.661	EPSD	COSMIC	3.097	Down-regulation
Other_ULK_ULK_ULK2_ST	O15027	SEC16A	Q8IYT8	ULK2	T819	T812A	812	Missense	distal	-7	no	3.672	3.670	EPSD	COSMIC	3.097	Down-regulation
Other_ULK_ULK_ULK2_ST	O15027	SEC16A	Q8IYT8	ULK2	T819	G814E	814	Missense	distal	-5	no	3.672	3.684	EPSD	COSMIC	3.097	Up-regulation
Other_ULK_ULK_ULK2_ST	O15027	SEC16A	Q8IYT8	ULK2	T819	T823I	823	Missense	distal	4	no	3.672	3.709	EPSD	COSMIC	3.097	Up-regulation
Other_ULK_ULK_ULK2_ST	O15027	SEC16A	Q8IYT8	ULK2	T819	T819A	819	Missense	central	0	yes	3.672	0.000	EPSD	COSMIC	3.097	Loss
Other_ULK_ULK_ULK2_ST	O15027	SEC16A	Q8IYT8	ULK2	S1044	S1048N	1048	Missense	distal	4	no	3.054	3.179	EPSD	COSMIC	3.097	Gain
Other_ULK_ULK_ULK2_ST	O15027	SEC16A	Q8IYT8	ULK2	S1044	E1039K	1039	Missense	distal	-5	no	3.054	3.103	EPSD	COSMIC;CCLE	3.097	Gain
Other_ULK_ULK_ULK2_ST	O15027	SEC16A	Q8IYT8	ULK2	S1044	P1038A	1038	Missense	distal	-6	no	3.054	3.117	EPSD	COSMIC	3.097	Gain
Other_ULK_ULK_ULK2_ST	O15027	SEC16A	Q8IYT8	ULK2	S1072	Y1065C	1065	Missense	distal	-7	no	3.541	3.545	EPSD	COSMIC	3.097	Up-regulation
Other_ULK_ULK_ULK2_ST	O15027	SEC16A	Q8IYT8	ULK2	S1072	S1075N	1075	Missense	distal	3	no	3.541	3.676	EPSD	COSMIC	3.097	Up-regulation
Other_ULK_ULK_ULK2_ST	O15027	SEC16A	Q8IYT8	ULK2	S1178	L1185P	1185	Missense	distal	7	no	4.301	4.268	EPSD	COSMIC	3.097	Down-regulation
Other_ULK_ULK_ULK2_ST	O15027	SEC16A	Q8IYT8	ULK2	S1178	A1176E	1176	Missense	proximal	-2	no	4.301	4.322	EPSD	COSMIC	3.097	Up-regulation
Other_ULK_ULK_ULK2_ST	O15027	SEC16A	Q8IYT8	ULK2	S1178	R1177W	1177	Missense	proximal	-1	no	4.301	4.572	EPSD	COSMIC	3.097	Up-regulation
Other_ULK_ULK_ULK2_ST	O15027	SEC16A	Q8IYT8	ULK2	S1178	A1182T	1182	Missense	distal	4	no	4.301	4.344	EPSD	COSMIC	3.097	Up-regulation
Other_ULK_ULK_ULK2_ST	O15027	SEC16A	Q8IYT8	ULK2	S1181	L1185P	1185	Missense	distal	4	no	3.183	3.216	EPSD	COSMIC	3.097	Up-regulation
Other_ULK_ULK_ULK2_ST	O15027	SEC16A	Q8IYT8	ULK2	S1181	A1176E	1176	Missense	distal	-5	no	3.183	3.108	EPSD	COSMIC	3.097	Down-regulation
Other_ULK_ULK_ULK2_ST	O15027	SEC16A	Q8IYT8	ULK2	S1181	R1188C	1188	Missense	distal	7	no	3.183	3.046	EPSD	COSMIC	3.097	Loss
Other_ULK_ULK_ULK2_ST	O15027	SEC16A	Q8IYT8	ULK2	S1181	R1177W	1177	Missense	distal	-4	no	3.183	3.274	EPSD	COSMIC	3.097	Up-regulation
Other_ULK_ULK_ULK2_ST	O15027	SEC16A	Q8IYT8	ULK2	S1181	A1182T	1182	Missense	proximal	1	no	3.183	3.466	EPSD	COSMIC	3.097	Up-regulation
Other_ULK_ULK_ULK2_ST	O15027	SEC16A	Q8IYT8	ULK2	S1184	R1189H	1189	Missense	distal	5	no	3.833	3.795	EPSD	COSMIC	3.097	Down-regulation
Other_ULK_ULK_ULK2_ST	O15027	SEC16A	Q8IYT8	ULK2	S1184	S1191C	1191	Missense	distal	7	no	3.833	3.717	EPSD	COSMIC	3.097	Down-regulation
Other_ULK_ULK_ULK2_ST	O15027	SEC16A	Q8IYT8	ULK2	S1184	L1185P	1185	Missense	proximal	1	no	3.833	2.912	EPSD	COSMIC	3.097	Loss
Other_ULK_ULK_ULK2_ST	O15027	SEC16A	Q8IYT8	ULK2	S1184	R1188C	1188	Missense	distal	4	no	3.833	3.754	EPSD	COSMIC	3.097	Down-regulation
Other_ULK_ULK_ULK2_ST	O15027	SEC16A	Q8IYT8	ULK2	S1184	R1177W	1177	Missense	distal	-7	no	3.833	3.777	EPSD	COSMIC	3.097	Down-regulation
Other_ULK_ULK_ULK2_ST	O15027	SEC16A	Q8IYT8	ULK2	S1184	A1182T	1182	Missense	proximal	-2	no	3.833	3.861	EPSD	COSMIC	3.097	Up-regulation
Other_ULK_ULK_ULK2_ST	O15027	SEC16A	Q8IYT8	ULK2	S1187	R1189H	1189	Missense	proximal	2	no	4.264	4.004	EPSD	COSMIC	3.097	Down-regulation
Other_ULK_ULK_ULK2_ST	O15027	SEC16A	Q8IYT8	ULK2	S1187	S1191C	1191	Missense	distal	4	no	4.264	4.411	EPSD	COSMIC	3.097	Up-regulation
Other_ULK_ULK_ULK2_ST	O15027	SEC16A	Q8IYT8	ULK2	S1187	L1185P	1185	Missense	proximal	-2	no	4.264	4.252	EPSD	COSMIC	3.097	Down-regulation
Other_ULK_ULK_ULK2_ST	O15027	SEC16A	Q8IYT8	ULK2	S1187	R1188C	1188	Missense	proximal	1	no	4.264	4.211	EPSD	COSMIC	3.097	Down-regulation
Other_ULK_ULK_ULK2_ST	O15027	SEC16A	Q8IYT8	ULK2	S1187	A1182T	1182	Missense	distal	-5	no	4.264	4.178	EPSD	COSMIC	3.097	Down-regulation
Other_ULK_ULK_ULK2_ST	O15027	SEC16A	Q8IYT8	ULK2	S1193	R1189H	1189	Missense	distal	-4	no	3.645	3.732	EPSD	COSMIC	3.097	Up-regulation
Other_ULK_ULK_ULK2_ST	O15027	SEC16A	Q8IYT8	ULK2	S1193	S1191C	1191	Missense	proximal	-2	no	3.645	3.619	EPSD	COSMIC	3.097	Down-regulation
Other_ULK_ULK_ULK2_ST	O15027	SEC16A	Q8IYT8	ULK2	S1193	H1197N	1197	Missense	distal	4	no	3.645	3.440	EPSD	COSMIC	3.097	Down-regulation
Other_ULK_ULK_ULK2_ST	O15027	SEC16A	Q8IYT8	ULK2	S1193	R1188C	1188	Missense	distal	-5	no	3.645	3.705	EPSD	COSMIC	3.097	Up-regulation
Other_ULK_ULK_ULK2_ST	O15027	SEC16A	Q8IYT8	ULK2	S1196	R1189H	1189	Missense	distal	-7	no	3.181	3.206	EPSD	COSMIC	3.097	Up-regulation
Other_ULK_ULK_ULK2_ST	O15027	SEC16A	Q8IYT8	ULK2	S1196	S1191C	1191	Missense	distal	-5	no	3.181	3.172	EPSD	COSMIC	3.097	Down-regulation
Other_ULK_ULK_ULK2_ST	O15027	SEC16A	Q8IYT8	ULK2	S1196	H1197N	1197	Missense	proximal	1	no	3.181	2.829	EPSD	COSMIC	3.097	Loss
Other_ULK_ULK_ULK2_ST	O15027	SEC16A	Q8IYT8	ULK2	S1199	H1197N	1197	Missense	proximal	-2	no	3.161	3.158	EPSD	COSMIC	3.097	Down-regulation
Other_ULK_ULK_ULK2_ST	O15027	SEC16A	Q8IYT8	ULK2	S1199	H1205Y	1205	Missense	distal	6	no	3.161	3.179	EPSD	COSMIC	3.097	Up-regulation
Other_ULK_ULK_ULK2_ST	O15027	SEC16A	Q8IYT8	ULK2	S1204	H1197N	1197	Missense	distal	-7	no	3.365	3.280	EPSD	COSMIC	3.097	Down-regulation
Other_ULK_ULK_ULK2_ST	O15027	SEC16A	Q8IYT8	ULK2	S1204	A1209S	1209	Missense	distal	5	no	3.365	3.468	EPSD	COSMIC	3.097	Up-regulation
Other_ULK_ULK_ULK2_ST	O15027	SEC16A	Q8IYT8	ULK2	S1204	H1205Y	1205	Missense	proximal	1	no	3.365	3.557	EPSD	COSMIC	3.097	Up-regulation
Other_ULK_ULK_ULK2_ST	O15027	SEC16A	Q8IYT8	ULK2	S1211	P1218Q	1218	Missense	distal	7	no	4.462	4.257	EPSD	COSMIC	3.097	Down-regulation
Other_ULK_ULK_ULK2_ST	O15027	SEC16A	Q8IYT8	ULK2	S1211	L1216P	1216	Missense	distal	5	no	4.462	4.508	EPSD	COSMIC	3.097	Up-regulation
Other_ULK_ULK_ULK2_ST	O15027	SEC16A	Q8IYT8	ULK2	S1211	A1209S	1209	Missense	proximal	-2	no	4.462	4.512	EPSD	COSMIC	3.097	Up-regulation
Other_ULK_ULK_ULK2_ST	O15027	SEC16A	Q8IYT8	ULK2	S1211	P1215L	1215	Missense	distal	4	no	4.462	4.428	EPSD	COSMIC	3.097	Down-regulation
Other_ULK_ULK_ULK2_ST	O15027	SEC16A	Q8IYT8	ULK2	S1211	H1205Y	1205	Missense	distal	-6	no	4.462	3.884	EPSD	COSMIC	3.097	Down-regulation
Other_ULK_ULK_ULK2_ST	O15027	SEC16A	Q8IYT8	ULK2	S1236	R1231W	1231	Missense	distal	-5	no	3.523	3.550	EPSD	COSMIC	3.097	Up-regulation
Other_ULK_ULK_ULK2_ST	O15027	SEC16A	Q8IYT8	ULK2	S1236	S1235N	1235	Missense	proximal	-1	no	3.523	3.335	EPSD	COSMIC;GDSC;CCLE	3.097	Down-regulation
Other_ULK_ULK_ULK2_ST	O15027	SEC16A	Q8IYT8	ULK2	S1236	R1231H	1231	Missense	distal	-5	no	3.523	3.420	EPSD	COSMIC;GDSC;CCLE	3.097	Down-regulation
Other_ULK_ULK_ULK2_ST	O15027	SEC16A	Q8IYT8	ULK2	S1259	R1260I	1260	Missense	proximal	1	no	2.535	3.202	EPSD	COSMIC	3.097	Gain
Other_ULK_ULK_ULK2_ST	O15027	SEC16A	Q8IYT8	ULK2	S1268	C1273S	1273	Missense	distal	5	no	3.055	3.097	EPSD	COSMIC	3.097	Gain
Other_ULK_ULK_ULK2_ST	O15027	SEC16A	Q8IYT8	ULK2	T1551	A1546P	1546	Missense	distal	-5	no	3.204	3.090	EPSD	COSMIC	3.097	Loss
Other_ULK_ULK_ULK2_ST	O15027	SEC16A	Q8IYT8	ULK2	T1551	M1548I	1548	Missense	distal	-3	no	3.204	3.112	EPSD	COSMIC	3.097	Down-regulation
Other_ULK_ULK_ULK2_ST	O15027	SEC16A	Q8IYT8	ULK2	T1551	T1547A	1547	Missense	distal	-4	no	3.204	3.078	EPSD	COSMIC	3.097	Loss
Other_ULK_ULK_ULK2_ST	O15027	SEC16A	Q8IYT8	ULK2	T1551	L1552P	1552	Missense	proximal	1	no	3.204	2.284	EPSD	COSMIC	3.097	Loss
Other_ULK_ULK_ULK2_ST	O15027	SEC16A	Q8IYT8	ULK2	S1554	M1548I	1548	Missense	distal	-6	no	3.259	3.529	EPSD	COSMIC	3.097	Up-regulation
Other_ULK_ULK_ULK2_ST	O15027	SEC16A	Q8IYT8	ULK2	S1554	T1547A	1547	Missense	distal	-7	no	3.259	3.257	EPSD	COSMIC	3.097	Down-regulation
Other_ULK_ULK_ULK2_ST	O15027	SEC16A	Q8IYT8	ULK2	S1554	A1561T	1561	Missense	distal	7	no	3.259	3.218	EPSD	COSMIC	3.097	Down-regulation
Other_ULK_ULK_ULK2_ST	O15027	SEC16A	Q8IYT8	ULK2	S1554	L1552P	1552	Missense	proximal	-2	no	3.259	3.247	EPSD	COSMIC	3.097	Down-regulation
Other_ULK_ULK_ULK2_ST	O15027	SEC16A	Q8IYT8	ULK2	S1554	A1560V	1560	Missense	distal	6	no	3.259	3.262	EPSD	COSMIC	3.097	Up-regulation
Other_ULK_ULK_ULK2_ST	O15027	SEC16A	Q8IYT8	ULK2	S1731	P1727S	1727	Missense	distal	-4	no	3.350	2.911	EPSD	COSMIC	3.097	Loss
Other_ULK_ULK_ULK2_ST	O15027	SEC16A	Q8IYT8	ULK2	S1766	P1767L	1767	Missense	proximal	1	no	2.378	3.298	EPSD	COSMIC	3.097	Gain
Other_ULK_ULK_ULK2_ST	O15027	SEC16A	Q8IYT8	ULK2	S1768	S1765L	1765	Missense	distal	-3	no	3.014	3.646	EPSD	COSMIC	3.097	Gain
Other_ULK_ULK_ULK2_ST	O15027	SEC16A	Q8IYT8	ULK2	S1768	P1767L	1767	Missense	proximal	-1	no	3.014	3.335	EPSD	COSMIC	3.097	Gain
Other_ULK_ULK_ULK2_ST	O15027	SEC16A	Q8IYT8	ULK2	S1844	P1851L	1851	Missense	distal	7	no	3.686	3.719	EPSD	COSMIC;GDSC	3.097	Up-regulation
Other_ULK_ULK_ULK2_ST	O15027	SEC16A	Q8IYT8	ULK2	S1859	L1860F	1860	Missense	proximal	1	no	3.477	3.357	EPSD	COSMIC	3.097	Down-regulation
Other_ULK_ULK_ULK2_ST	O15027	SEC16A	Q8IYT8	ULK2	S1859	E1862K	1862	Missense	distal	3	no	3.477	3.528	EPSD	COSMIC	3.097	Up-regulation
Other_ULK_ULK_ULK2_ST	O15027	SEC16A	Q8IYT8	ULK2	S1859	E1865K	1865	Missense	distal	6	no	3.477	3.459	EPSD	COSMIC	3.097	Down-regulation
Other_ULK_ULK_ULK2_ST	O15027	SEC16A	Q8IYT8	ULK2	S1859	E1866D	1866	Missense	distal	7	no	3.477	3.392	EPSD	COSMIC	3.097	Down-regulation
Other_ULK_ULK_ULK2_ST	O15027	SEC16A	Q8IYT8	ULK2	S1903	E1909K	1909	Missense	distal	6	no	3.218	3.199	EPSD	COSMIC	3.097	Down-regulation
Other_ULK_ULK_ULK2_ST	O15027	SEC16A	Q8IYT8	ULK2	S1981	P1975S	1975	Missense	distal	-6	no	3.951	3.774	EPSD	COSMIC	3.097	Down-regulation
Other_ULK_ULK_ULK2_ST	O15027	SEC16A	Q8IYT8	ULK2	S1981	P1975L	1975	Missense	distal	-6	no	3.951	3.932	EPSD	COSMIC	3.097	Down-regulation
Other_ULK_ULK_ULK2_ST	O15027	SEC16A	Q8IYT8	ULK2	S1981	P1983S	1983	Missense	proximal	2	no	3.951	3.737	EPSD	COSMIC	3.097	Down-regulation
Other_ULK_ULK_ULK2_ST	O15027	SEC16A	Q8IYT8	ULK2	S1981	P1978S	1978	Missense	distal	-3	no	3.951	3.984	EPSD	COSMIC;CCLE	3.097	Up-regulation
Other_ULK_ULK_ULK2_ST	O15027	SEC16A	Q8IYT8	ULK2	S2113	S2119N	2119	Missense	distal	6	no	3.771	3.750	EPSD	COSMIC	3.097	Down-regulation
Other_ULK_ULK_ULK2_ST	O15027	SEC16A	Q8IYT8	ULK2	S2117	S2119N	2119	Missense	proximal	2	no	3.662	3.809	EPSD	COSMIC	3.097	Up-regulation
Other_ULK_ULK_ULK2_ST	O15027	SEC16A	Q8IYT8	ULK2	S2122	S2119N	2119	Missense	distal	-3	no	3.690	3.938	EPSD	COSMIC	3.097	Up-regulation
Other_ULK_ULK_ULK2_ST	A2RUS2	DENND3	Q8IYT8	ULK2	S368	I369M	369	Missense	proximal	1	no	3.130	3.055	EPSD	COSMIC	3.097	Loss
Other_ULK_ULK_ULK2_ST	A2RUS2	DENND3	Q8IYT8	ULK2	S472	H466Q	466	Missense	distal	-6	no	9.056	8.438	PhosphoSitePlus;EPSD	COSMIC	3.097	Down-regulation
Other_ULK_ULK_ULK2_ST	A2RUS2	DENND3	Q8IYT8	ULK2	S490	S490N	490	Missense	central	0	yes	9.018	0.000	EPSD;PhosphoSitePlus	COSMIC	3.097	Loss
Other_ULK_ULK_ULK2_ST	A2RUS2	DENND3	Q8IYT8	ULK2	S490	R492W	492	Missense	proximal	2	no	9.018	8.409	EPSD;PhosphoSitePlus	COSMIC	3.097	Down-regulation
Other_ULK_ULK_ULK2_ST	A2RUS2	DENND3	Q8IYT8	ULK2	S490	L491P	491	Missense	proximal	1	no	9.018	8.098	EPSD;PhosphoSitePlus	COSMIC	3.097	Down-regulation
Other_ULK_ULK_ULK2_ST	A2RUS2	DENND3	Q8IYT8	ULK2	S503	T509M	509	Missense	distal	6	no	3.204	3.200	EPSD	COSMIC;GDSC;CCLE	3.097	Down-regulation
Other_ULK_ULK_ULK2_ST	A2RUS2	DENND3	Q8IYT8	ULK2	S503	P510T	510	Missense	distal	7	no	3.204	3.120	EPSD	COSMIC	3.097	Down-regulation
Other_ULK_ULK_ULK2_ST	A2RUS2	DENND3	Q8IYT8	ULK2	S503	R500K	500	Missense	distal	-3	no	3.204	2.495	EPSD	COSMIC	3.097	Loss
Other_ULK_ULK_ULK2_ST	A2RUS2	DENND3	Q8IYT8	ULK2	T1172	C1174R	1174	Missense	proximal	2	no	2.637	3.280	EPSD	COSMIC	3.097	Gain
Other_PEK_HRI_EIF2AK1_ST	P05198	EIF2S1	Q9BQI3	EIF2AK1	S49	R54W	54	Missense	distal	5	no	7.554	7.523	EPSD;PhosphoSitePlus	GDSC;CCLE	2.464	Down-regulation
Other_PEK_HRI_EIF2AK1_ST	P05198	EIF2S1	Q9BQI3	EIF2AK1	S52	R54W	54	Missense	proximal	2	no	8.502	8.484	PhosphoSitePlus;EPSD	GDSC;CCLE	2.464	Down-regulation
AGC_PKC_PKCd_PRKCD_ST	Q9UQL6	HDAC5	Q05655	PRKCD	S1108	E1114Q	1114	Missense	distal	6	no	13.327	13.334	EPSD	GDSC	7.604	Up-regulation
AGC_PKC_PKCd_PRKCD_ST	P18433	PTPRA	Q05655	PRKCD	S189	G195V	195	Missense	distal	6	no	10.453	10.444	EPSD	GDSC	7.604	Down-regulation
AGC_PKC_PKCd_PRKCD_ST	P18433	PTPRA	Q05655	PRKCD	S193	G195V	195	Missense	proximal	2	no	7.813	7.774	EPSD	GDSC	7.604	Down-regulation
AGC_PKC_PKCd_PRKCD_ST	P18433	PTPRA	Q05655	PRKCD	T672	S670T	670	Missense	proximal	-2	no	8.225	7.111	EPSD	GDSC	7.604	Loss
AGC_PKC_PKCd_PRKCD_ST	Q9UQ13	SHOC2	Q05655	PRKCD	S85	P79H	79	Missense	distal	-6	no	11.553	11.578	EPSD	GDSC;CCLE	7.604	Up-regulation
AGC_PKC_PKCd_PRKCD_ST	Q9UQ13	SHOC2	Q05655	PRKCD	S86	P79H	79	Missense	distal	-7	no	11.454	11.449	EPSD	GDSC;CCLE	7.604	Down-regulation
AGC_PKC_PKCd_PRKCD_ST	Q9UQ13	SHOC2	Q05655	PRKCD	S221	K226T	226	Missense	distal	5	no	10.060	9.673	EPSD	GDSC;CCLE	7.604	Down-regulation
AGC_PKC_PKCd_PRKCD_ST	Q9UQ13	SHOC2	Q05655	PRKCD	S297	A304V	304	Missense	distal	7	no	10.402	10.364	EPSD;PhosphoSitePlus	GDSC;CCLE	7.604	Down-regulation
AGC_PKC_PKCd_PRKCD_ST	P53004	BLVRA	Q05655	PRKCD	S21	R18G	18	Missense	distal	-3	no	15.400	10.191	EPSD;PhosphoSitePlus	GDSC	7.604	Down-regulation
AGC_PKC_PKCd_PRKCD_ST	P35611	ADD1	Q05655	PRKCD	S404	E411A	411	Missense	distal	7	no	12.122	12.141	EPSD	GDSC;CCLE	7.604	Up-regulation
AGC_PKC_PKCd_PRKCD_ST	P35611	ADD1	Q05655	PRKCD	S408	S415T	415	Missense	distal	7	no	11.745	11.737	EPSD	GDSC	7.604	Down-regulation
AGC_PKC_PKCd_PRKCD_ST	P35611	ADD1	Q05655	PRKCD	S408	E411A	411	Missense	distal	3	no	11.745	11.997	EPSD	GDSC;CCLE	7.604	Up-regulation
AGC_PKC_PKCd_PRKCD_ST	P35611	ADD1	Q05655	PRKCD	S408	A414V	414	Missense	distal	6	no	11.745	11.728	EPSD	GDSC;CCLE	7.604	Down-regulation
AGC_PKC_PKCd_PRKCD_ST	P35611	ADD1	Q05655	PRKCD	S481	H478Y	478	Missense	distal	-3	no	8.617	6.993	EPSD	GDSC	7.604	Loss
AGC_PKC_PKCd_PRKCD_ST	P14598	NCF1	Q05655	PRKCD	T45	H51L	51	Missense	distal	6	no	9.067	9.055	EPSD	GDSC	7.604	Down-regulation
AGC_PKC_PKCd_PRKCD_ST	P14598	NCF1	Q05655	PRKCD	T45	V40G	40	Missense	distal	-5	no	9.067	9.083	EPSD	GDSC	7.604	Up-regulation
AGC_PKC_PKCd_PRKCD_ST	P14598	NCF1	Q05655	PRKCD	T93	Q91K	91	Missense	proximal	-2	no	3.602	7.791	EPSD	GDSC;CCLE	7.604	Gain
AGC_PKC_PKCd_PRKCD_ST	P14598	NCF1	Q05655	PRKCD	S320	Y324H	324	Missense	distal	4	no	9.608	9.861	EPSD;PhosphoSitePlus	GDSC;CCLE	7.604	Up-regulation
AGC_PKC_PKCd_PRKCD_ST	P14598	NCF1	Q05655	PRKCD	S328	Y324H	324	Missense	distal	-4	no	17.699	17.538	EPSD;PhosphoSitePlus	GDSC;CCLE	7.604	Down-regulation
AGC_PKC_PKCd_PRKCD_ST	P15407	FOSL1	Q05655	PRKCD	S251	S246*	246	Missense	distal	-5	no	9.698	9.320	EPSD	GDSC	7.604	Down-regulation
AGC_PKC_PKCd_PRKCD_ST	P15407	FOSL1	Q05655	PRKCD	S252	S246*	246	Missense	distal	-6	no	11.747	12.249	EPSD	GDSC	7.604	Up-regulation
AGC_PKC_PKCd_PRKCD_ST	Q9UBS0	RPS6KB2	Q05655	PRKCD	S416	R419Q	419	Missense	distal	3	no	9.315	8.237	EPSD	GDSC;CCLE	7.604	Down-regulation
AGC_PKC_PKCd_PRKCD_ST	Q9UBS0	RPS6KB2	Q05655	PRKCD	S468	R465C	465	Missense	distal	-3	no	11.931	6.612	EPSD	GDSC;CCLE	7.604	Loss
AGC_PKC_PKCd_PRKCD_ST	Q9UBS0	RPS6KB2	Q05655	PRKCD	T470	R465C	465	Missense	distal	-5	no	9.021	8.544	EPSD	GDSC;CCLE	7.604	Down-regulation
AGC_PKC_PKCd_PRKCD_ST	Q9H257	CARD9	Q05655	PRKCD	S431	Q436R	436	Missense	distal	5	no	10.159	10.493	EPSD	GDSC;CCLE	7.604	Up-regulation
AGC_PKC_PKCd_PRKCD_ST	P05107	ITGB2	Q05655	PRKCD	S496	K499N	499	Missense	distal	3	no	8.090	6.955	EPSD	GDSC;CCLE	7.604	Loss
AGC_PKC_PKCd_PRKCD_ST	Q05655	PRKCD	Q05655	PRKCD	S299	S304P	304	Missense	distal	5	no	13.252	13.284	EPSD;PhosphoSitePlus	GDSC;CCLE	7.604	Up-regulation
AGC_PKC_PKCd_PRKCD_ST	Q05655	PRKCD	Q05655	PRKCD	S302	S304P	304	Missense	proximal	2	no	9.128	9.372	EPSD;PhosphoSitePlus	GDSC;CCLE	7.604	Up-regulation
AGC_PKC_PKCd_PRKCD_ST	Q05655	PRKCD	Q05655	PRKCD	S304	S304P	304	Missense	central	0	yes	8.265	0.000	EPSD;PhosphoSitePlus	GDSC;CCLE	7.604	Loss
AGC_PKC_PKCd_PRKCD_ST	Q05655	PRKCD	Q05655	PRKCD	S559	T564M	564	Missense	distal	5	no	8.200	8.038	EPSD	GDSC	7.604	Down-regulation
AGC_PKC_PKCd_PRKCD_ST	P13796	LCP1	Q05655	PRKCD	T503	W496*	496	Missense	distal	-7	no	9.340	9.336	EPSD	GDSC	7.604	Down-regulation
AGC_PKC_PKCd_PRKCD_ST	Q9HBA0	TRPV4	Q05655	PRKCD	S189	T193I	193	Missense	distal	4	no	7.627	7.375	EPSD;PhosphoSitePlus	GDSC;CCLE	7.604	Loss
AGC_PKC_PKCd_PRKCD_ST	Q13501	SQSTM1	Q05655	PRKCD	T269	E274K	274	Missense	distal	5	no	7.197	7.635	EPSD	GDSC;CCLE	7.604	Gain
AGC_PKC_PKCd_PRKCD_ST	Q13501	SQSTM1	Q05655	PRKCD	S272	E274K	274	Missense	proximal	2	no	3.706	9.461	EPSD	GDSC;CCLE	7.604	Gain
AGC_PKC_PKCd_PRKCD_ST	Q13501	SQSTM1	Q05655	PRKCD	S276	E274K	274	Missense	proximal	-2	no	3.700	8.680	EPSD	GDSC;CCLE	7.604	Gain
AGC_PKC_PKCd_PRKCD_ST	Q13501	SQSTM1	Q05655	PRKCD	S277	E274K	274	Missense	distal	-3	no	3.550	7.935	EPSD	GDSC;CCLE	7.604	Gain
AGC_PKC_PKCd_PRKCD_ST	P05787	KRT8	Q05655	PRKCD	S2	T6S	6	Missense	distal	4	no	7.619	7.654	EPSD	GDSC;CCLE	7.604	Up-regulation
AGC_PKC_PKCd_PRKCD_ST	P05787	KRT8	Q05655	PRKCD	S9	T6S	6	Missense	distal	-3	no	8.549	9.066	EPSD	GDSC;CCLE	7.604	Up-regulation
AGC_PKC_PKCd_PRKCD_ST	P05787	KRT8	Q05655	PRKCD	S13	T6S	6	Missense	distal	-7	no	8.045	8.050	EPSD	GDSC;CCLE	7.604	Up-regulation
AGC_PKC_PKCd_PRKCD_ST	P05787	KRT8	Q05655	PRKCD	S74	L76R	76	Missense	proximal	2	no	2.522	9.399	PhosphoSitePlus	GDSC;CCLE	7.604	Gain
AGC_PKC_PKCd_PRKCD_ST	P05787	KRT8	Q05655	PRKCD	S456	T455A	455	Missense	proximal	-1	no	9.616	9.600	EPSD	GDSC	7.604	Down-regulation
AGC_PKC_PKCd_PRKCD_ST	P05787	KRT8	Q05655	PRKCD	S457	T455A	455	Missense	proximal	-2	no	13.673	14.825	EPSD	GDSC	7.604	Up-regulation
AGC_PKC_PKCd_PRKCD_ST	P04406	GAPDH	Q05655	PRKCD	S25	T19A	19	Missense	distal	-6	no	9.327	9.404	EPSD	GDSC;CCLE	7.604	Up-regulation
AGC_PKC_PKCd_PRKCD_ST	P51398	DAP3	Q05655	PRKCD	S31	A33T	33	Missense	proximal	2	no	9.607	8.575	PhosphoSitePlus;EPSD	GDSC;CCLE	7.604	Down-regulation
AGC_PKC_PKCd_PRKCD_ST	P51398	DAP3	Q05655	PRKCD	S44	E43K	43	Missense	proximal	-1	no	8.907	9.081	EPSD	GDSC;CCLE	7.604	Up-regulation
AGC_PKC_PKCd_PRKCD_ST	P51398	DAP3	Q05655	PRKCD	S44	A47G	47	Missense	distal	3	no	8.907	8.693	EPSD	GDSC;CCLE	7.604	Down-regulation
AGC_PKC_PKCd_PRKCD_ST	P51398	DAP3	Q05655	PRKCD	T273	L268F	268	Missense	distal	-5	no	11.344	11.390	EPSD	GDSC	7.604	Up-regulation
AGC_PKC_PKCd_PRKCD_ST	P62753	RPS6	Q05655	PRKCD	S235	S242F	242	Missense	distal	7	no	16.067	16.019	PhosphoSitePlus;EPSD	GDSC	7.604	Down-regulation
AGC_PKC_PKCd_PRKCD_ST	P62753	RPS6	Q05655	PRKCD	S236	S242F	242	Missense	distal	6	no	14.320	14.293	EPSD;PhosphoSitePlus	GDSC	7.604	Down-regulation
AGC_PKC_PKCd_PRKCD_ST	P62753	RPS6	Q05655	PRKCD	S240	S242F	242	Missense	proximal	2	no	9.107	9.050	EPSD	GDSC	7.604	Down-regulation
AGC_PKC_PKCd_PRKCD_ST	P62753	RPS6	Q05655	PRKCD	T241	S242F	242	Missense	proximal	1	no	12.317	12.267	EPSD	GDSC	7.604	Down-regulation
AGC_PKC_PKCd_PRKCD_ST	Q14247	CTTN	Q05655	PRKCD	S109	E103K	103	Missense	distal	-6	no	7.847	7.428	EPSD	GDSC;CCLE	7.604	Loss
AGC_PKC_PKCd_PRKCD_ST	Q14247	CTTN	Q05655	PRKCD	S109	V115A	115	Missense	distal	6	no	7.847	7.864	EPSD	GDSC;CCLE	7.604	Up-regulation
AGC_PKC_PKCd_PRKCD_ST	Q14247	CTTN	Q05655	PRKCD	S113	V115A	115	Missense	proximal	2	no	7.527	8.674	EPSD	GDSC;CCLE	7.604	Gain
AGC_PKC_PKCd_PRKCD_ST	Q14247	CTTN	Q05655	PRKCD	S117	V115A	115	Missense	proximal	-2	no	7.793	8.424	EPSD	GDSC;CCLE	7.604	Up-regulation
AGC_PKC_PKCd_PRKCD_ST	P98082	DAB2	Q05655	PRKCD	S24	K28R	28	Missense	distal	4	no	12.739	12.747	PhosphoSitePlus	GDSC;CCLE	7.604	Up-regulation
AGC_PKC_PKCd_PRKCD_ST	P98082	DAB2	Q05655	PRKCD	S249	S249Y	249	Missense	central	0	yes	8.261	0.000	EPSD	GDSC;CCLE	7.604	Loss
AGC_PKC_PKCd_PRKCD_ST	P98082	DAB2	Q05655	PRKCD	S367	W364R	364	Missense	distal	-3	no	2.371	7.667	EPSD	GDSC	7.604	Gain
AGC_PKC_PKCd_PRKCD_ST	P98082	DAB2	Q05655	PRKCD	S436	R441K	441	Missense	distal	5	no	10.180	10.241	EPSD	GDSC;CCLE	7.604	Up-regulation
AGC_PKC_PKCd_PRKCD_ST	P98082	DAB2	Q05655	PRKCD	S436	I430V	430	Missense	distal	-6	no	10.180	10.154	EPSD	GDSC	7.604	Down-regulation
AGC_PKC_PKCd_PRKCD_ST	Q9Y2R2	PTPN22	Q05655	PRKCD	S692	S692C	692	Missense	central	0	yes	9.496	0.000	EPSD	GDSC	7.604	Loss
AGC_PKC_PKCd_PRKCD_ST	Q9Y2R2	PTPN22	Q05655	PRKCD	S692	P695S	695	Missense	distal	3	no	9.496	9.502	EPSD	GDSC;CCLE	7.604	Up-regulation
AGC_PKC_PKCd_PRKCD_ST	Q9Y2R2	PTPN22	Q05655	PRKCD	S751	S751N	751	Missense	central	0	yes	11.808	0.000	EPSD	GDSC	7.604	Loss
AGC_PKC_PKCd_PRKCD_ST	Q15139	PRKD1	Q05655	PRKCD	S397	N403S	403	Missense	distal	6	no	8.054	8.081	EPSD	GDSC	7.604	Up-regulation
AGC_PKC_PKCd_PRKCD_ST	Q15139	PRKD1	Q05655	PRKCD	S412	R408M	408	Missense	distal	-4	no	8.277	8.671	EPSD;PhosphoSitePlus	GDSC;CCLE	7.604	Up-regulation
AGC_PKC_PKCd_PRKCD_ST	Q15139	PRKD1	Q05655	PRKCD	S829	K826E	826	Missense	distal	-3	no	11.806	7.421	EPSD	GDSC;CCLE	7.604	Loss
AGC_PKC_PKCd_PRKCD_ST	P05230	FGF1	Q05655	PRKCD	S131	V124A	124	Missense	distal	-7	no	12.592	12.598	PhosphoSitePlus	GDSC;CCLE	7.604	Up-regulation
AGC_PKC_PKCd_PRKCD_ST	P17405	SMPD1	Q05655	PRKCD	S7	M1T	1	Missense	distal	-6	no	8.709	8.511	EPSD	GDSC	7.604	Down-regulation
AGC_PKC_PKCd_PRKCD_ST	P28329	CHAT	Q05655	PRKCD	S377	E382K	382	Missense	distal	5	no	8.071	8.509	EPSD	GDSC;CCLE	7.604	Up-regulation
AGC_PKC_PKCd_PRKCD_ST	P28329	CHAT	Q05655	PRKCD	S464	S465R	465	Missense	proximal	1	no	9.423	9.517	EPSD	GDSC;CCLE	7.604	Up-regulation
AGC_PKC_PKCd_PRKCD_ST	P28329	CHAT	Q05655	PRKCD	S473	P478L	478	Missense	distal	5	no	8.924	8.702	EPSD	GDSC;CCLE	7.604	Down-regulation
AGC_PKC_PKCd_PRKCD_ST	P28329	CHAT	Q05655	PRKCD	S473	P480S	480	Missense	distal	7	no	8.924	8.953	EPSD	GDSC;CCLE	7.604	Up-regulation
AGC_PKC_PKCd_PRKCD_ST	P28329	CHAT	Q05655	PRKCD	S473	P480L	480	Missense	distal	7	no	8.924	8.894	EPSD	GDSC;CCLE	7.604	Down-regulation
AGC_PKC_PKCd_PRKCD_ST	P28329	CHAT	Q05655	PRKCD	S558	E555D	555	Missense	distal	-3	no	9.671	10.052	EPSD	GDSC;CCLE	7.604	Up-regulation
AGC_PKC_PKCd_PRKCD_ST	P28329	CHAT	Q05655	PRKCD	S594	A590D	590	Missense	distal	-4	no	9.664	9.710	EPSD	GDSC;CCLE	7.604	Up-regulation
AGC_PKC_PKCd_PRKCD_ST	P04637	TP53	Q05655	PRKCD	S99	K101*	101	Missense	proximal	2	no	8.382	0.897	EPSD	GDSC	7.604	Loss
AGC_PKC_PKCd_PRKCD_ST	P04637	TP53	Q05655	PRKCD	S99	Q100*	100	Missense	proximal	1	no	8.382	8.209	EPSD	GDSC	7.604	Down-regulation
AGC_PKC_PKCd_PRKCD_ST	P04637	TP53	Q05655	PRKCD	S99	S94*	94	Missense	distal	-5	no	8.382	8.004	EPSD	GDSC	7.604	Down-regulation
AGC_PKC_PKCd_PRKCD_ST	P04637	TP53	Q05655	PRKCD	S183	S183*	183	Missense	central	0	yes	7.852	0.000	EPSD	GDSC	7.604	Loss
AGC_PKC_PKCd_PRKCD_ST	P04637	TP53	Q05655	PRKCD	S183	E180*	180	Missense	distal	-3	no	7.852	6.581	EPSD	GDSC	7.604	Loss
AGC_PKC_PKCd_PRKCD_ST	P04637	TP53	Q05655	PRKCD	T211	R213*	213	Missense	proximal	2	no	12.679	4.016	EPSD	GDSC	7.604	Loss
AGC_PKC_PKCd_PRKCD_ST	P04637	TP53	Q05655	PRKCD	T211	R209*	209	Missense	proximal	-2	no	12.679	5.058	EPSD	GDSC	7.604	Loss
AGC_PKC_PKCd_PRKCD_ST	P04637	TP53	Q05655	PRKCD	T211	E204*	204	Missense	distal	-7	no	12.679	12.662	EPSD	GDSC	7.604	Down-regulation
AGC_PKC_PKCd_PRKCD_ST	P04637	TP53	Q05655	PRKCD	S215	R213*	213	Missense	proximal	-2	no	7.714	0.094	EPSD	GDSC	7.604	Loss
AGC_PKC_PKCd_PRKCD_ST	P04637	TP53	Q05655	PRKCD	S215	R209*	209	Missense	distal	-6	no	7.714	8.417	EPSD	GDSC	7.604	Up-regulation
AGC_PKC_PKCd_PRKCD_ST	P04637	TP53	Q05655	PRKCD	S269	E271*	271	Missense	proximal	2	no	8.933	7.203	EPSD	GDSC	7.604	Loss
AGC_PKC_PKCd_PRKCD_ST	P04637	TP53	Q05655	PRKCD	S366	G360V	360	Missense	distal	-6	no	9.437	9.489	EPSD	GDSC;CCLE	7.604	Up-regulation
AGC_PKC_PKCd_PRKCD_ST	P06401	PGR	Q05655	PRKCD	S276	F275S	275	Missense	proximal	-1	no	10.275	10.382	EPSD	GDSC;CCLE	7.604	Up-regulation
AGC_PKC_PKCd_PRKCD_ST	P06401	PGR	Q05655	PRKCD	S397	E395G	395	Missense	proximal	-2	no	8.825	9.287	EPSD	GDSC;CCLE	7.604	Up-regulation
AGC_PKC_PKCd_PRKCD_ST	P06401	PGR	Q05655	PRKCD	S400	E395G	395	Missense	distal	-5	no	10.978	10.948	PhosphoSitePlus	GDSC;CCLE	7.604	Down-regulation
AGC_PKC_PKCd_PRKCD_ST	Q8TCU6	PREX1	Q05655	PRKCD	T308	R303W	303	Missense	distal	-5	no	8.800	8.255	EPSD	GDSC	7.604	Down-regulation
AGC_PKC_PKCd_PRKCD_ST	Q8TCU6	PREX1	Q05655	PRKCD	S310	R303W	303	Missense	distal	-7	no	7.760	7.726	EPSD	GDSC	7.604	Down-regulation
AGC_PKC_PKCd_PRKCD_ST	Q8TCU6	PREX1	Q05655	PRKCD	S993	P986T	986	Missense	distal	-7	no	14.544	14.540	EPSD	GDSC;CCLE	7.604	Down-regulation
AGC_PKC_PKCd_PRKCD_ST	Q8TCU6	PREX1	Q05655	PRKCD	S993	R995H	995	Missense	proximal	2	no	14.544	8.983	EPSD	GDSC;CCLE	7.604	Down-regulation
AGC_PKC_PKCd_PRKCD_ST	Q8TCU6	PREX1	Q05655	PRKCD	S1001	R995H	995	Missense	distal	-6	no	11.614	11.916	EPSD	GDSC;CCLE	7.604	Up-regulation
AGC_PKC_PKCd_PRKCD_ST	P78536	ADAM17	Q05655	PRKCD	T87	Q92K	92	Missense	distal	5	no	7.297	7.693	EPSD	GDSC;CCLE	7.604	Gain
AGC_PKC_PKCd_PRKCD_ST	P21730	C5AR1	Q05655	PRKCD	S314	L315H	315	Missense	proximal	1	no	8.341	8.355	EPSD	GDSC;CCLE	7.604	Up-regulation
AGC_PKC_PKCd_PRKCD_ST	P21730	C5AR1	Q05655	PRKCD	S332	T339A	339	Missense	distal	7	no	9.823	9.805	EPSD	GDSC;CCLE	7.604	Down-regulation
AGC_PKC_PKCd_PRKCD_ST	P21730	C5AR1	Q05655	PRKCD	S332	R337H	337	Missense	distal	5	no	9.823	9.471	EPSD	GDSC;CCLE	7.604	Down-regulation
AGC_PKC_PKCd_PRKCD_ST	P35568	IRS1	Q05655	PRKCD	S24	H26R	26	Missense	proximal	2	no	11.075	16.635	EPSD	GDSC;CCLE	7.604	Up-regulation
AGC_PKC_PKCd_PRKCD_ST	P35568	IRS1	Q05655	PRKCD	S268	R267C	267	Missense	proximal	-1	no	8.493	8.282	EPSD	GDSC;CCLE	7.604	Down-regulation
AGC_PKC_PKCd_PRKCD_ST	P35568	IRS1	Q05655	PRKCD	S270	R267C	267	Missense	distal	-3	no	9.706	4.386	EPSD	GDSC;CCLE	7.604	Loss
AGC_PKC_PKCd_PRKCD_ST	P35568	IRS1	Q05655	PRKCD	S362	R364W	364	Missense	proximal	2	no	14.525	7.852	EPSD	GDSC	7.604	Down-regulation
AGC_PKC_PKCd_PRKCD_ST	P35568	IRS1	Q05655	PRKCD	S362	P368A	368	Missense	distal	6	no	14.525	14.513	EPSD	GDSC;CCLE	7.604	Down-regulation
AGC_PKC_PKCd_PRKCD_ST	P35568	IRS1	Q05655	PRKCD	S383	R381C	381	Missense	proximal	-2	no	7.873	1.879	EPSD	GDSC;CCLE	7.604	Loss
AGC_PKC_PKCd_PRKCD_ST	P35568	IRS1	Q05655	PRKCD	S383	A386S	386	Missense	distal	3	no	7.873	7.939	EPSD	GDSC;CCLE	7.604	Up-regulation
AGC_PKC_PKCd_PRKCD_ST	P35568	IRS1	Q05655	PRKCD	S383	P376L	376	Missense	distal	-7	no	7.873	7.862	EPSD	GDSC;CCLE	7.604	Down-regulation
AGC_PKC_PKCd_PRKCD_ST	P35568	IRS1	Q05655	PRKCD	S412	R411*	411	Missense	proximal	-1	no	8.948	8.631	EPSD	GDSC	7.604	Down-regulation
AGC_PKC_PKCd_PRKCD_ST	P35568	IRS1	Q05655	PRKCD	S413	R411*	411	Missense	proximal	-2	no	12.056	4.435	EPSD	GDSC	7.604	Loss
AGC_PKC_PKCd_PRKCD_ST	P35568	IRS1	Q05655	PRKCD	S603	G597E	597	Missense	distal	-6	no	8.411	8.388	EPSD	GDSC	7.604	Down-regulation
AGC_PKC_PKCd_PRKCD_ST	P35568	IRS1	Q05655	PRKCD	S636	A642S	642	Missense	distal	6	no	10.727	10.745	EPSD	GDSC;CCLE	7.604	Up-regulation
AGC_PKC_PKCd_PRKCD_ST	P35568	IRS1	Q05655	PRKCD	S641	A642S	642	Missense	proximal	1	no	7.529	7.609	EPSD	GDSC;CCLE	7.604	Gain
AGC_PKC_PKCd_PRKCD_ST	P35568	IRS1	Q05655	PRKCD	S869	L871F	871	Missense	proximal	2	no	8.590	9.347	EPSD	GDSC;CCLE	7.604	Up-regulation
AGC_PKC_PKCd_PRKCD_ST	P35568	IRS1	Q05655	PRKCD	T870	L871F	871	Missense	proximal	1	no	7.797	7.802	EPSD	GDSC;CCLE	7.604	Up-regulation
AGC_PKC_PKCd_PRKCD_ST	P35568	IRS1	Q05655	PRKCD	S1084	S1084R	1084	Missense	central	0	yes	12.466	0.000	EPSD	GDSC	7.604	Loss
AGC_PKC_PKCd_PRKCD_ST	P35568	IRS1	Q05655	PRKCD	S1084	A1085D	1085	Missense	proximal	1	no	12.466	12.469	EPSD	GDSC;CCLE	7.604	Up-regulation
AGC_PKC_PKCd_PRKCD_ST	P35568	IRS1	Q05655	PRKCD	S1084	R1089G	1089	Missense	distal	5	no	12.466	12.023	EPSD	GDSC;CCLE	7.604	Down-regulation
AGC_PKC_PKCd_PRKCD_ST	P35568	IRS1	Q05655	PRKCD	S1100	R1096G	1096	Missense	distal	-4	no	12.851	13.236	EPSD	GDSC;CCLE	7.604	Up-regulation
AGC_PKC_PKCd_PRKCD_ST	P35568	IRS1	Q05655	PRKCD	S1101	R1096G	1096	Missense	distal	-5	no	9.221	8.808	EPSD	GDSC;CCLE	7.604	Down-regulation
AGC_PKC_PKCd_PRKCD_ST	P35568	IRS1	Q05655	PRKCD	S1218	S1218P	1218	Missense	central	0	yes	11.542	0.000	EPSD	GDSC	7.604	Loss
AGC_PKC_PKCd_PRKCD_ST	P35568	IRS1	Q05655	PRKCD	T1219	S1218P	1218	Missense	proximal	-1	no	8.904	8.864	EPSD	GDSC	7.604	Down-regulation
AGC_PKC_PKCd_PRKCD_ST	P35568	IRS1	Q05655	PRKCD	S1222	S1218P	1218	Missense	distal	-4	no	8.311	8.332	EPSD	GDSC	7.604	Up-regulation
AGC_PKC_PKCd_PRKCD_ST	P35568	IRS1	Q05655	PRKCD	S1223	S1218P	1218	Missense	distal	-5	no	13.549	13.540	EPSD	GDSC	7.604	Down-regulation
AGC_PKC_PKCd_PRKCD_ST	Q9NRY6	PLSCR3	Q05655	PRKCD	S230	R227W	227	Missense	distal	-3	no	8.291	2.995	EPSD	GDSC	7.604	Loss
AGC_PKC_PKCd_PRKCD_ST	P53671	LIMK2	Q05655	PRKCD	S298	S297F	297	Missense	proximal	-1	no	8.307	8.200	EPSD	GDSC	7.604	Down-regulation
AGC_PKC_PKCd_PRKCD_ST	P23396	RPS3	Q05655	PRKCD	S139	R143Q	143	Missense	distal	4	no	7.778	7.190	EPSD	GDSC;CCLE	7.604	Loss
AGC_PKC_PKCd_PRKCD_ST	P23396	RPS3	Q05655	PRKCD	S149	G155D	155	Missense	distal	6	no	12.233	12.239	EPSD	GDSC;CCLE	7.604	Up-regulation
AGC_PKC_PKCd_PRKCD_ST	P23396	RPS3	Q05655	PRKCD	S149	R143Q	143	Missense	distal	-6	no	12.233	12.536	EPSD	GDSC;CCLE	7.604	Up-regulation
AGC_PKC_PKCd_PRKCD_ST	O14939	PLD2	Q05655	PRKCD	S155	R149Q	149	Missense	distal	-6	no	8.536	8.838	EPSD	GDSC;CCLE	7.604	Up-regulation
AGC_PKC_PKCd_PRKCD_ST	O14939	PLD2	Q05655	PRKCD	T274	R281W	281	Missense	distal	7	no	13.611	13.446	EPSD	GDSC;CCLE	7.604	Down-regulation
AGC_PKC_PKCd_PRKCD_ST	O14939	PLD2	Q05655	PRKCD	T274	Q268*	268	Missense	distal	-6	no	13.611	14.011	EPSD	GDSC	7.604	Up-regulation
AGC_PKC_PKCd_PRKCD_ST	O14939	PLD2	Q05655	PRKCD	S493	P487T	487	Missense	distal	-6	no	9.471	9.435	EPSD	GDSC;CCLE	7.604	Down-regulation
AGC_PKC_PKCd_PRKCD_ST	O95817	BAG3	Q05655	PRKCD	S165	G167R	167	Missense	proximal	2	no	3.080	9.412	EPSD	GDSC;CCLE	7.604	Gain
AGC_PKC_PKCd_PRKCD_ST	O95817	BAG3	Q05655	PRKCD	S173	G167R	167	Missense	distal	-6	no	8.090	7.698	EPSD	GDSC;CCLE	7.604	Down-regulation
AGC_PKC_PKCd_PRKCD_ST	O95817	BAG3	Q05655	PRKCD	S191	S187N	187	Missense	distal	-4	no	9.348	9.502	EPSD	GDSC;CCLE	7.604	Up-regulation
AGC_PKC_PKCd_PRKCD_ST	O95817	BAG3	Q05655	PRKCD	S264	F266S	266	Missense	proximal	2	no	8.309	8.365	EPSD	GDSC;CCLE	7.604	Up-regulation
AGC_PKC_PKCd_PRKCD_ST	O95817	BAG3	Q05655	PRKCD	S269	R276Q	276	Missense	distal	7	no	7.782	7.691	EPSD	GDSC	7.604	Down-regulation
AGC_PKC_PKCd_PRKCD_ST	O95817	BAG3	Q05655	PRKCD	S269	F266S	266	Missense	distal	-3	no	7.782	7.730	EPSD	GDSC;CCLE	7.604	Down-regulation
AGC_PKC_PKCd_PRKCD_ST	O95817	BAG3	Q05655	PRKCD	S279	R276Q	276	Missense	distal	-3	no	9.528	4.371	EPSD	GDSC	7.604	Loss
AGC_PKC_PKCd_PRKCD_ST	O95817	BAG3	Q05655	PRKCD	S359	E360*	360	Missense	proximal	1	no	8.570	8.409	EPSD	GDSC	7.604	Down-regulation
AGC_PKC_PKCd_PRKCD_ST	O95817	BAG3	Q05655	PRKCD	S386	P380S	380	Missense	distal	-6	no	8.821	8.744	EPSD	GDSC	7.604	Down-regulation
AGC_PKC_PKCd_PRKCD_ST	P29353	SHC1	Q05655	PRKCD	S17	L13F	13	Missense	distal	-4	no	9.086	9.057	EPSD	GDSC;CCLE	7.604	Down-regulation
AGC_PKC_PKCd_PRKCD_ST	P29353	SHC1	Q05655	PRKCD	S17	L18F	18	Missense	proximal	1	no	9.086	9.092	EPSD	GDSC	7.604	Up-regulation
AGC_PKC_PKCd_PRKCD_ST	P29353	SHC1	Q05655	PRKCD	S80	G82E	82	Missense	proximal	2	no	7.765	7.164	EPSD	GDSC	7.604	Loss
AGC_PKC_PKCd_PRKCD_ST	P29353	SHC1	Q05655	PRKCD	S139	T145P	145	Missense	distal	6	no	9.770	9.771	EPSD	GDSC;CCLE	7.604	Up-regulation
AGC_PKC_PKCd_PRKCD_ST	O00165	HAX1	Q05655	PRKCD	S212	K209R	209	Missense	distal	-3	no	7.164	8.200	EPSD	GDSC;CCLE	7.604	Gain
AGC_PKC_PKCd_PRKCD_ST	P35222	CTNNB1	Q05655	PRKCD	S179	H176Y	176	Missense	distal	-3	no	8.737	7.113	EPSD	GDSC;CCLE	7.604	Loss
AGC_PKC_PKCd_PRKCD_ST	P35222	CTNNB1	Q05655	PRKCD	T547	R549H	549	Missense	proximal	2	no	10.676	5.115	EPSD	GDSC;CCLE	7.604	Loss
AGC_PKC_PKCd_PRKCD_ST	P35222	CTNNB1	Q05655	PRKCD	S552	R549H	549	Missense	distal	-3	no	13.381	9.127	EPSD	GDSC;CCLE	7.604	Down-regulation
AGC_PKC_PKCd_PRKCD_ST	P35222	CTNNB1	Q05655	PRKCD	S675	Y670*	670	Missense	distal	-5	no	11.304	11.128	EPSD	GDSC	7.604	Down-regulation
AGC_PKC_PKCd_PRKCD_ST	Q96C90	PPP1R14B	Q05655	PRKCD	T57	Q53E	53	Missense	distal	-4	no	8.969	9.019	PhosphoSitePlus	GDSC;CCLE	7.604	Up-regulation
AGC_PKC_PKCd_PRKCD_ST	Q96C90	PPP1R14B	Q05655	PRKCD	S142	G137S	137	Missense	distal	-5	no	8.494	8.633	EPSD	GDSC;CCLE	7.604	Up-regulation
AGC_PKC_PKCd_PRKCD_ST	Q96C90	PPP1R14B	Q05655	PRKCD	S142	R136Q	136	Missense	distal	-6	no	8.494	8.797	EPSD	GDSC;CCLE	7.604	Up-regulation
AGC_PKC_PKCd_PRKCD_ST	P49841	GSK3B	Q05655	PRKCD	T7	T8P	8	Missense	proximal	1	no	7.670	7.707	EPSD	GDSC	7.604	Up-regulation
AGC_PKC_PKCd_PRKCD_ST	P49841	GSK3B	Q05655	PRKCD	S9	T8P	8	Missense	proximal	-1	no	8.872	8.893	PhosphoSitePlus	GDSC	7.604	Up-regulation
AGC_PKC_PKCd_PRKCD_ST	P49841	GSK3B	Q05655	PRKCD	S13	T8P	8	Missense	distal	-5	no	9.596	9.613	EPSD	GDSC	7.604	Up-regulation
AGC_PKC_PKCd_PRKCD_ST	P49841	GSK3B	Q05655	PRKCD	S25	S21L	21	Missense	distal	-4	no	10.292	10.453	EPSD	GDSC;CCLE	7.604	Up-regulation
AGC_PKC_PKCd_PRKCD_ST	O00429	DNM1L	Q05655	PRKCD	T78	E82*	82	Missense	distal	4	no	9.612	9.190	EPSD	GDSC	7.604	Down-regulation
AGC_PKC_PKCd_PRKCD_ST	O00429	DNM1L	Q05655	PRKCD	T79	E82*	82	Missense	distal	3	no	8.492	7.918	EPSD	GDSC	7.604	Down-regulation
AGC_PKC_PKCd_PRKCD_ST	O00429	DNM1L	Q05655	PRKCD	S637	V632A	632	Missense	distal	-5	no	18.032	18.118	EPSD	GDSC;CCLE	7.604	Up-regulation
AGC_PKC_PKCd_PRKCD_ST	Q01543	FLI1	Q05655	PRKCD	S79	S86G	86	Missense	distal	7	no	8.546	8.501	EPSD	GDSC;CCLE	7.604	Down-regulation
AGC_PKC_PKCd_PRKCD_ST	Q01543	FLI1	Q05655	PRKCD	S215	L214F	214	Missense	proximal	-1	no	13.714	13.723	EPSD	GDSC;CCLE	7.604	Up-regulation
AGC_PKC_PKCd_PRKCD_ST	Q9UQ80	PA2G4	Q05655	PRKCD	T261	S262L	262	Missense	proximal	1	no	9.778	9.723	EPSD	GDSC;CCLE	7.604	Down-regulation
AGC_PKC_PKCd_PRKCD_ST	Q9UQ80	PA2G4	Q05655	PRKCD	S262	S262L	262	Missense	central	0	yes	7.689	0.000	EPSD	GDSC;CCLE	7.604	Loss
AGC_PKC_PKCd_PRKCD_ST	Q9UQ80	PA2G4	Q05655	PRKCD	T279	A275V	275	Missense	distal	-4	no	8.141	8.226	EPSD	GDSC;CCLE	7.604	Up-regulation
AGC_PKC_PKCd_PRKCD_ST	Q9UQ80	PA2G4	Q05655	PRKCD	S363	Q359*	359	Missense	distal	-4	no	10.325	10.629	EPSD	GDSC	7.604	Up-regulation
AGC_PKC_PKCd_PRKCD_ST	Q9UQ80	PA2G4	Q05655	PRKCD	T366	Q359*	359	Missense	distal	-7	no	12.737	12.716	EPSD	GDSC	7.604	Down-regulation
AGC_PKC_PKCd_PRKCD_ST	P04040	CAT	Q05655	PRKCD	S167	F161V	161	Missense	distal	-6	no	8.389	8.426	PhosphoSitePlus	GDSC	7.604	Up-regulation
AGC_PKC_PKCd_PRKCD_ST	P12931	SRC	Q05655	PRKCD	S180	T183M	183	Missense	distal	3	no	8.337	8.206	EPSD	GDSC	7.604	Down-regulation
AGC_PKC_PKCd_PRKCD_ST	P52757	CHN2	Q05655	PRKCD	S85	A79T	79	Missense	distal	-6	no	13.564	13.486	EPSD	GDSC;CCLE	7.604	Down-regulation
AGC_PKC_PKCd_PRKCD_ST	P52757	CHN2	Q05655	PRKCD	S167	V166A	166	Missense	proximal	-1	no	11.819	11.869	EPSD	GDSC;CCLE	7.604	Up-regulation
AGC_PKC_PKCd_PRKCD_ST	P52757	CHN2	Q05655	PRKCD	S171	V166A	166	Missense	distal	-5	no	12.251	12.337	PhosphoSitePlus	GDSC;CCLE	7.604	Up-regulation
AGC_PKC_PKCd_PRKCD_ST	P30086	PEBP1	Q05655	PRKCD	S52	L58H	58	Missense	distal	6	no	7.624	7.637	EPSD	GDSC	7.604	Up-regulation
AGC_PKC_PKCd_PRKCD_ST	P30086	PEBP1	Q05655	PRKCD	S52	P50A	50	Missense	proximal	-2	no	7.624	7.277	EPSD	GDSC;CCLE	7.604	Loss
AGC_PKC_PKCd_PRKCD_ST	Q8IV61	RASGRP3	Q05655	PRKCD	T133	K140*	140	Missense	distal	7	no	19.126	18.901	PhosphoSitePlus	GDSC	7.604	Down-regulation
AGC_PKC_PKCd_PRKCD_ST	Q8IV61	RASGRP3	Q05655	PRKCD	S385	S387*	387	Missense	proximal	2	no	8.525	5.926	EPSD	GDSC	7.604	Loss
AGC_PKC_PKCd_PRKCD_ST	Q8IV61	RASGRP3	Q05655	PRKCD	S552	A548T	548	Missense	distal	-4	no	8.325	8.294	EPSD	GDSC;CCLE	7.604	Down-regulation
AGC_PKC_PKCd_PRKCD_ST	Q8IV61	RASGRP3	Q05655	PRKCD	S552	G558A	558	Missense	distal	6	no	8.325	8.333	EPSD	GDSC;CCLE	7.604	Up-regulation
CAMK_PIM_PIM2_ST	P52789	HK2	Q9P1W9	PIM2	T473	R470H	470	Missense	distal	-3	no	7.049	5.871	PhosphoSitePlus	GDSC;CCLE	4.322	Down-regulation
CAMK_PIM_PIM2_ST	P38936	CDKN1A	Q9P1W9	PIM2	S31	L37P	37	Missense	distal	6	no	4.430	4.533	EPSD	GDSC	4.322	Up-regulation
CAMK_PIM_PIM2_ST	P38936	CDKN1A	Q9P1W9	PIM2	S31	Q29R	29	Missense	proximal	-2	no	4.430	5.154	EPSD	GDSC;CCLE	4.322	Up-regulation
CAMK_PIM_PIM2_ST	P38936	CDKN1A	Q9P1W9	PIM2	T145	R143Q	143	Missense	proximal	-2	no	11.610	10.886	PhosphoSitePlus;EPSD	GDSC;CCLE	4.322	Down-regulation
CAMK_PIM_PIM2_ST	P38936	CDKN1A	Q9P1W9	PIM2	S146	R143Q	143	Missense	distal	-3	no	9.959	8.314	EPSD;PhosphoSitePlus	GDSC;CCLE	4.322	Down-regulation
CAMK_PIM_PIM2_ST	P35568	IRS1	Q9P1W9	PIM2	S270	R267C	267	Missense	distal	-3	no	5.498	3.851	EPSD	GDSC;CCLE	4.322	Loss
CAMK_PIM_PIM2_ST	P35568	IRS1	Q9P1W9	PIM2	S272	R267C	267	Missense	distal	-5	no	5.034	2.025	EPSD	GDSC;CCLE	4.322	Loss
CAMK_PIM_PIM2_ST	P35568	IRS1	Q9P1W9	PIM2	S415	R411*	411	Missense	distal	-4	no	5.097	5.210	EPSD	GDSC	4.322	Up-regulation
CAMK_PIM_PIM2_ST	P35568	IRS1	Q9P1W9	PIM2	S641	A642S	642	Missense	proximal	1	no	4.990	4.921	EPSD	GDSC;CCLE	4.322	Down-regulation
CAMK_PIM_PIM2_ST	P35568	IRS1	Q9P1W9	PIM2	S736	P737S	737	Missense	proximal	1	no	4.364	4.487	EPSD	GDSC	4.322	Up-regulation
CAMK_PIM_PIM2_ST	P35568	IRS1	Q9P1W9	PIM2	T859	R854C	854	Missense	distal	-5	no	5.482	2.473	EPSD	GDSC	4.322	Loss
CAMK_PIM_PIM2_ST	P35568	IRS1	Q9P1W9	PIM2	T938	P931L	931	Missense	distal	-7	no	4.540	4.177	EPSD	GDSC;CCLE	4.322	Loss
CAMK_PIM_PIM2_ST	P35568	IRS1	Q9P1W9	PIM2	S1101	R1096G	1096	Missense	distal	-5	no	12.128	8.792	PhosphoSitePlus	GDSC;CCLE	4.322	Down-regulation
CAMK_CAMK2_CAMK2A_ST	Q14524	SCN5A	Q9UQM7	CAMK2A	S11	S11I	11	Missense	central	0	yes	7.285	0.000	EPSD;PhosphoSitePlus	GDSC;CCLE	4.810	Loss
CAMK_CAMK2_CAMK2A_ST	Q14524	SCN5A	Q9UQM7	CAMK2A	S12	S11I	11	Missense	proximal	-1	no	5.341	5.167	EPSD;PhosphoSitePlus	GDSC;CCLE	4.810	Down-regulation
CAMK_CAMK2_CAMK2A_ST	Q14524	SCN5A	Q9UQM7	CAMK2A	T17	S11I	11	Missense	distal	-6	no	8.351	8.327	EPSD;PhosphoSitePlus	GDSC;CCLE	4.810	Down-regulation
CAMK_CAMK2_CAMK2A_ST	Q14524	SCN5A	Q9UQM7	CAMK2A	S516	T512I	512	Missense	distal	-4	no	7.724	7.627	EPSD;PhosphoSitePlus	GDSC;CCLE	4.810	Down-regulation
CAMK_CAMK2_CAMK2A_ST	Q14524	SCN5A	Q9UQM7	CAMK2A	S571	A572D	572	Missense	proximal	1	no	6.593	6.380	EPSD;PhosphoSitePlus	GDSC	4.810	Down-regulation
CAMK_CAMK2_CAMK2A_ST	Q14524	SCN5A	Q9UQM7	CAMK2A	S571	T570I	570	Missense	proximal	-1	no	6.593	6.580	EPSD;PhosphoSitePlus	GDSC;CCLE	4.810	Down-regulation
CAMK_CAMK2_CAMK2A_ST	Q14524	SCN5A	Q9UQM7	CAMK2A	S571	P576H	576	Missense	distal	5	no	6.593	6.795	EPSD;PhosphoSitePlus	GDSC;CCLE	4.810	Up-regulation
CAMK_CAMK2_CAMK2A_ST	Q14524	SCN5A	Q9UQM7	CAMK2A	S571	R569G	569	Missense	proximal	-2	no	6.593	6.363	EPSD;PhosphoSitePlus	GDSC;CCLE	4.810	Down-regulation
CAMK_CAMK2_CAMK2A_ST	Q14524	SCN5A	Q9UQM7	CAMK2A	S581	P576H	576	Missense	distal	-5	no	4.885	4.759	EPSD	GDSC;CCLE	4.810	Loss
CAMK_CAMK2_CAMK2A_ST	Q14524	SCN5A	Q9UQM7	CAMK2A	T594	N598H	598	Missense	distal	4	no	7.816	7.836	EPSD	GDSC;CCLE	4.810	Up-regulation
CAMK_CAMK2_CAMK2A_ST	Q14524	SCN5A	Q9UQM7	CAMK2A	S664	S671N	671	Missense	distal	7	no	7.191	7.237	EPSD;PhosphoSitePlus	GDSC;CCLE	4.810	Up-regulation
CAMK_CAMK2_CAMK2A_ST	P35367	HRH1	Q9UQM7	CAMK2A	S363	S363P	363	Missense	central	0	yes	6.631	0.000	EPSD	GDSC	4.810	Loss
CAMK_CAMK2_CAMK2A_ST	P15036	ETS2	Q9UQM7	CAMK2A	S246	S245C	245	Missense	proximal	-1	no	8.446	8.029	EPSD;PhosphoSitePlus	GDSC	4.810	Down-regulation
CAMK_CAMK2_CAMK2A_ST	P15036	ETS2	Q9UQM7	CAMK2A	S289	F286S	286	Missense	distal	-3	no	-3.549	5.538	EPSD	GDSC;CCLE	4.810	Gain
CAMK_CAMK2_CAMK2A_ST	Q9Y618	NCOR2	Q9UQM7	CAMK2A	S88	E94G	94	Missense	distal	6	no	6.621	6.542	EPSD	GDSC;CCLE	4.810	Down-regulation
CAMK_CAMK2_CAMK2A_ST	Q9Y618	NCOR2	Q9UQM7	CAMK2A	S140	S140N	140	Missense	central	0	yes	5.987	0.000	EPSD	GDSC;CCLE	4.810	Loss
CAMK_CAMK2_CAMK2A_ST	Q9Y618	NCOR2	Q9UQM7	CAMK2A	T550	K549R	549	Missense	proximal	-1	no	5.344	5.194	EPSD	GDSC	4.810	Down-regulation
CAMK_CAMK2_CAMK2A_ST	Q9Y618	NCOR2	Q9UQM7	CAMK2A	T550	E543K	543	Missense	distal	-7	no	5.344	5.236	EPSD	GDSC;CCLE	4.810	Down-regulation
CAMK_CAMK2_CAMK2A_ST	Q9Y618	NCOR2	Q9UQM7	CAMK2A	S939	T946P	946	Missense	distal	7	no	7.929	7.933	EPSD	GDSC	4.810	Up-regulation
CAMK_CAMK2_CAMK2A_ST	Q14654	KCNJ11	Q9UQM7	CAMK2A	T224	K222Q	222	Missense	proximal	-2	no	5.257	5.298	EPSD;PhosphoSitePlus	GDSC;CCLE	4.810	Up-regulation
CAMK_CAMK2_CAMK2A_ST	O15273	TCAP	Q9UQM7	CAMK2A	T109	E105Q	105	Missense	distal	-4	no	5.609	5.447	EPSD	GDSC	4.810	Down-regulation
CAMK_CAMK2_CAMK2A_ST	O15273	TCAP	Q9UQM7	CAMK2A	S157	R153H	153	Missense	distal	-4	no	9.266	9.142	PhosphoSitePlus;EPSD	GDSC	4.810	Down-regulation
CAMK_CAMK2_CAMK2A_ST	O15273	TCAP	Q9UQM7	CAMK2A	S159	R153H	153	Missense	distal	-6	no	4.874	4.827	EPSD	GDSC	4.810	Down-regulation
CAMK_CAMK2_CAMK2A_ST	P28329	CHAT	Q9UQM7	CAMK2A	S125	E128*	128	Missense	distal	3	no	6.995	6.348	EPSD	GDSC	4.810	Down-regulation
CAMK_CAMK2_CAMK2A_ST	P28329	CHAT	Q9UQM7	CAMK2A	S473	P478L	478	Missense	distal	5	no	8.060	8.001	EPSD	GDSC;CCLE	4.810	Down-regulation
CAMK_CAMK2_CAMK2A_ST	P28329	CHAT	Q9UQM7	CAMK2A	S473	P480S	480	Missense	distal	7	no	8.060	7.962	EPSD	GDSC;CCLE	4.810	Down-regulation
CAMK_CAMK2_CAMK2A_ST	P28329	CHAT	Q9UQM7	CAMK2A	S473	P480L	480	Missense	distal	7	no	8.060	8.125	EPSD	GDSC;CCLE	4.810	Up-regulation
CAMK_CAMK2_CAMK2A_ST	P35270	SPR	Q9UQM7	CAMK2A	S213	R219*	219	Missense	distal	6	no	9.050	8.870	PhosphoSitePlus	GDSC	4.810	Down-regulation
CAMK_CAMK2_CAMK2A_ST	P35270	SPR	Q9UQM7	CAMK2A	S243	F250V	250	Missense	distal	7	no	6.278	6.108	EPSD	GDSC;CCLE	4.810	Down-regulation
CAMK_CAMK2_CAMK2A_ST	P43003	SLC1A3	Q9UQM7	CAMK2A	T26	Q19*	19	Missense	distal	-7	no	7.224	7.662	PhosphoSitePlus;EPSD	GDSC	4.810	Up-regulation
CAMK_CAMK2_CAMK2A_ST	Q15796	SMAD2	Q9UQM7	CAMK2A	S465	S464*	464	Missense	proximal	-1	no	7.825	7.375	EPSD	GDSC	4.810	Down-regulation
CAMK_CAMK2_CAMK2A_ST	P46527	CDKN1B	Q9UQM7	CAMK2A	T157	P155L	155	Missense	proximal	-2	no	8.037	7.927	EPSD	GDSC;CCLE	4.810	Down-regulation
CAMK_CAMK2_CAMK2A_ST	P46527	CDKN1B	Q9UQM7	CAMK2A	S175	G177S	177	Missense	proximal	2	no	5.426	5.421	EPSD	GDSC;CCLE	4.810	Down-regulation
CAMK_CAMK2_CAMK2A_ST	P46527	CDKN1B	Q9UQM7	CAMK2A	S183	G177S	177	Missense	distal	-6	no	5.521	5.428	EPSD	GDSC;CCLE	4.810	Down-regulation
CAMK_CAMK2_CAMK2A_ST	P11831	SRF	Q9UQM7	CAMK2A	S372	A365D	365	Missense	distal	-7	no	4.910	5.359	EPSD	GDSC;CCLE	4.810	Up-regulation
CAMK_CAMK2_CAMK2A_ST	Q92736	RYR2	Q9UQM7	CAMK2A	S2031	R2026H	2026	Missense	distal	-5	no	6.199	6.145	EPSD	GDSC	4.810	Down-regulation
CAMK_CAMK2_CAMK2A_ST	Q9UQL6	HDAC5	Q9UQM7	CAMK2A	S1108	E1114Q	1114	Missense	distal	6	no	9.007	8.996	EPSD	GDSC	4.810	Down-regulation
CAMK_CAMK2_CAMK2A_ST	O14713	ITGB1BP1	Q9UQM7	CAMK2A	S25	S28F	28	Missense	distal	3	no	9.192	8.815	EPSD	GDSC;CCLE	4.810	Down-regulation
CAMK_CAMK2_CAMK2A_ST	P31645	SLC6A4	Q9UQM7	CAMK2A	S13	A14V	14	Missense	proximal	1	no	5.858	6.210	PhosphoSitePlus	GDSC;CCLE	4.810	Up-regulation
CAMK_CAMK2_CAMK2A_ST	P31645	SLC6A4	Q9UQM7	CAMK2A	S40	N45S	45	Missense	distal	5	no	6.166	6.279	EPSD	GDSC;CCLE	4.810	Up-regulation
CAMK_CAMK2_CAMK2A_ST	P21333	FLNA	Q9UQM7	CAMK2A	S123	K127N	127	Missense	distal	4	no	7.119	7.086	EPSD	GDSC;CCLE	4.810	Down-regulation
CAMK_CAMK2_CAMK2A_ST	P21333	FLNA	Q9UQM7	CAMK2A	S343	P348L	348	Missense	distal	5	no	5.546	5.487	EPSD	GDSC;CCLE	4.810	Down-regulation
CAMK_CAMK2_CAMK2A_ST	P21333	FLNA	Q9UQM7	CAMK2A	S343	R340H	340	Missense	distal	-3	no	5.546	0.049	EPSD	GDSC	4.810	Loss
CAMK_CAMK2_CAMK2A_ST	P21333	FLNA	Q9UQM7	CAMK2A	S440	Q447*	447	Missense	distal	7	no	4.755	5.114	EPSD	GDSC	4.810	Gain
CAMK_CAMK2_CAMK2A_ST	P21333	FLNA	Q9UQM7	CAMK2A	S512	Y506C	506	Missense	distal	-6	no	4.723	4.842	EPSD	GDSC;CCLE	4.810	Gain
CAMK_CAMK2_CAMK2A_ST	P21333	FLNA	Q9UQM7	CAMK2A	S630	R634G	634	Missense	distal	4	no	6.038	6.112	EPSD	GDSC	4.810	Up-regulation
CAMK_CAMK2_CAMK2A_ST	P21333	FLNA	Q9UQM7	CAMK2A	S748	W749L	749	Missense	proximal	1	no	4.247	5.015	EPSD	GDSC	4.810	Gain
CAMK_CAMK2_CAMK2A_ST	P21333	FLNA	Q9UQM7	CAMK2A	T1275	S1279N	1279	Missense	distal	4	no	6.437	6.357	EPSD	GDSC;CCLE	4.810	Down-regulation
CAMK_CAMK2_CAMK2A_ST	P21333	FLNA	Q9UQM7	CAMK2A	T1286	S1279N	1279	Missense	distal	-7	no	7.466	7.563	EPSD	GDSC;CCLE	4.810	Up-regulation
CAMK_CAMK2_CAMK2A_ST	P21333	FLNA	Q9UQM7	CAMK2A	T1286	R1283Q	1283	Missense	distal	-3	no	7.466	3.895	EPSD	GDSC;CCLE	4.810	Loss
CAMK_CAMK2_CAMK2A_ST	P21333	FLNA	Q9UQM7	CAMK2A	S1423	G1420S	1420	Missense	distal	-3	no	5.362	5.500	EPSD	GDSC;CCLE	4.810	Up-regulation
CAMK_CAMK2_CAMK2A_ST	P21333	FLNA	Q9UQM7	CAMK2A	S1423	V1426I	1426	Missense	distal	3	no	5.362	5.139	EPSD	GDSC;CCLE	4.810	Down-regulation
CAMK_CAMK2_CAMK2A_ST	P21333	FLNA	Q9UQM7	CAMK2A	S1812	A1816V	1816	Missense	distal	4	no	6.255	6.201	EPSD	GDSC;CCLE	4.810	Down-regulation
CAMK_CAMK2_CAMK2A_ST	P21333	FLNA	Q9UQM7	CAMK2A	S1812	R1809Q	1809	Missense	distal	-3	no	6.255	2.684	EPSD	GDSC;CCLE	4.810	Loss
CAMK_CAMK2_CAMK2A_ST	P21333	FLNA	Q9UQM7	CAMK2A	S1906	E1903K	1903	Missense	distal	-3	no	2.883	5.734	EPSD	GDSC	4.810	Gain
CAMK_CAMK2_CAMK2A_ST	P21333	FLNA	Q9UQM7	CAMK2A	S2284	I2283L	2283	Missense	proximal	-1	no	6.163	6.126	EPSD	GDSC	4.810	Down-regulation
CAMK_CAMK2_CAMK2A_ST	P21333	FLNA	Q9UQM7	CAMK2A	T2336	R2334C	2334	Missense	proximal	-2	no	5.750	4.947	EPSD	GDSC	4.810	Down-regulation
CAMK_CAMK2_CAMK2A_ST	P21333	FLNA	Q9UQM7	CAMK2A	S2352	P2350A	2350	Missense	proximal	-2	no	5.610	5.711	EPSD	GDSC;CCLE	4.810	Up-regulation
CAMK_CAMK2_CAMK2A_ST	O43526	KCNQ2	Q9UQM7	CAMK2A	S445	V443A	443	Missense	proximal	-2	no	7.611	8.028	EPSD	GDSC;CCLE	4.810	Up-regulation
CAMK_CAMK2_CAMK2A_ST	O43526	KCNQ2	Q9UQM7	CAMK2A	S445	V450M	450	Missense	distal	5	no	7.611	7.603	EPSD	GDSC	4.810	Down-regulation
CAMK_CAMK2_CAMK2A_ST	O43526	KCNQ2	Q9UQM7	CAMK2A	S457	P458L	458	Missense	proximal	1	no	4.369	5.028	EPSD	GDSC	4.810	Gain
CAMK_CAMK2_CAMK2A_ST	O43526	KCNQ2	Q9UQM7	CAMK2A	S468	S468R	468	Missense	central	0	yes	9.877	0.000	EPSD	GDSC;CCLE	4.810	Loss
CAMK_CAMK2_CAMK2A_ST	O43526	KCNQ2	Q9UQM7	CAMK2A	S503	R497H	497	Missense	distal	-6	no	4.957	4.910	EPSD	GDSC;CCLE	4.810	Down-regulation
CAMK_CAMK2_CAMK2A_ST	P35222	CTNNB1	Q9UQM7	CAMK2A	S552	R549H	549	Missense	distal	-3	no	8.308	2.810	PhosphoSitePlus;EPSD	GDSC;CCLE	4.810	Loss
CAMK_CAMK2_CAMK2A_ST	P35222	CTNNB1	Q9UQM7	CAMK2A	S675	Y670*	670	Missense	distal	-5	no	6.091	6.137	EPSD	GDSC	4.810	Up-regulation
CAMK_CAMK2_CAMK2A_ST	O14490	DLGAP1	Q9UQM7	CAMK2A	S134	S132C	132	Missense	proximal	-2	no	7.707	6.975	EPSD	GDSC;CCLE	4.810	Down-regulation
CAMK_CAMK2_CAMK2A_ST	O14490	DLGAP1	Q9UQM7	CAMK2A	S346	M351I	351	Missense	distal	5	no	6.665	6.571	EPSD	GDSC;CCLE	4.810	Down-regulation
CAMK_CAMK2_CAMK2A_ST	O14490	DLGAP1	Q9UQM7	CAMK2A	S493	S491T	491	Missense	proximal	-2	no	7.165	7.122	EPSD	GDSC;CCLE	4.810	Down-regulation
CAMK_CAMK2_CAMK2A_ST	P09917	ALOX5	Q9UQM7	CAMK2A	T105	F98L	98	Missense	distal	-7	no	6.840	6.374	EPSD	GDSC;CCLE	4.810	Down-regulation
CAMK_CAMK2_CAMK2A_ST	P41134	ID1	Q9UQM7	CAMK2A	S5	G6C	6	Missense	proximal	1	no	4.710	4.991	EPSD	GDSC;CCLE	4.810	Gain
CAMK_CAMK2_CAMK2A_ST	P41134	ID1	Q9UQM7	CAMK2A	S36	E30Q	30	Missense	distal	-6	no	5.316	5.392	PhosphoSitePlus	GDSC;CCLE	4.810	Up-regulation
CAMK_CAMK2_CAMK2A_ST	P55055	NR1H2	Q9UQM7	CAMK2A	S426	T429M	429	Missense	distal	3	no	6.813	6.827	PhosphoSitePlus	GDSC;CCLE	4.810	Up-regulation
CAMK_CAMK2_CAMK2A_ST	P51790	CLCN3	Q9UQM7	CAMK2A	S109	R106W	106	Missense	distal	-3	no	8.332	-3.689	PhosphoSitePlus	GDSC;CCLE	4.810	Loss
CAMK_CAMK2_CAMK2A_ST	P40189	IL6ST	Q9UQM7	CAMK2A	S782	V776A	776	Missense	distal	-6	no	8.741	8.586	PhosphoSitePlus	GDSC;CCLE	4.810	Down-regulation
CAMK_CAMK2_CAMK2A_ST	P40189	IL6ST	Q9UQM7	CAMK2A	T890	E886Q	886	Missense	distal	-4	no	7.308	7.145	EPSD	GDSC;CCLE	4.810	Down-regulation
CAMK_CAMK2_CAMK2A_ST	Q00613	HSF1	Q9UQM7	CAMK2A	T120	N114S	114	Missense	distal	-6	no	7.050	6.948	EPSD	GDSC;CCLE	4.810	Down-regulation
CAMK_CAMK2_CAMK2A_ST	Q00613	HSF1	Q9UQM7	CAMK2A	S121	N114S	114	Missense	distal	-7	no	5.278	5.181	EPSD	GDSC;CCLE	4.810	Down-regulation
CAMK_CAMK2_CAMK2A_ST	Q00613	HSF1	Q9UQM7	CAMK2A	S290	R296H	296	Missense	distal	6	no	6.695	6.670	EPSD	GDSC;CCLE	4.810	Down-regulation
CAMK_CAMK2_CAMK2A_ST	Q00613	HSF1	Q9UQM7	CAMK2A	T355	R360Q	360	Missense	distal	5	no	6.031	6.030	EPSD	GDSC	4.810	Down-regulation
CAMK_CAMK2_CAMK2A_ST	Q00613	HSF1	Q9UQM7	CAMK2A	T355	R360W	360	Missense	distal	5	no	6.031	5.656	EPSD	GDSC;CCLE	4.810	Down-regulation
CAMK_CAMK2_CAMK2A_ST	Q00613	HSF1	Q9UQM7	CAMK2A	S363	R360Q	360	Missense	distal	-3	no	6.498	2.927	EPSD	GDSC	4.810	Loss
CAMK_CAMK2_CAMK2A_ST	Q00613	HSF1	Q9UQM7	CAMK2A	S363	R360W	360	Missense	distal	-3	no	6.498	-5.522	EPSD	GDSC;CCLE	4.810	Loss
CAMK_CAMK2_CAMK2A_ST	Q00613	HSF1	Q9UQM7	CAMK2A	S458	S458I	458	Missense	central	0	yes	4.973	0.000	EPSD	GDSC;CCLE	4.810	Loss
CAMK_CAMK2_CAMK2A_ST	Q4G163	FBXO43	Q9UQM7	CAMK2A	S385	S381P	381	Missense	distal	-4	no	6.448	6.070	EPSD	GDSC;CCLE	4.810	Down-regulation
CAMK_CAMK2_CAMK2A_ST	P55042	RRAD	Q9UQM7	CAMK2A	S257	Q250R	250	Missense	distal	-7	no	7.537	7.480	EPSD	GDSC;CCLE	4.810	Down-regulation
CAMK_CAMK2_CAMK2A_ST	P16949	STMN1	Q9UQM7	CAMK2A	S16	E10K	10	Missense	distal	-6	no	6.341	6.442	PhosphoSitePlus	GDSC;CCLE	4.810	Up-regulation
CAMK_CAMK2_CAMK2A_ST	P16949	STMN1	Q9UQM7	CAMK2A	S16	E10*	10	Missense	distal	-6	no	6.341	6.629	PhosphoSitePlus	GDSC	4.810	Up-regulation
CAMK_CAMK2_CAMK2A_ST	P16949	STMN1	Q9UQM7	CAMK2A	S139	E138*	138	Missense	proximal	-1	no	6.940	6.245	EPSD	GDSC	4.810	Down-regulation
CAMK_CAMK2_CAMK2A_ST	Q9Y496	KIF3A	Q9UQM7	CAMK2A	S207	K204R	204	Missense	distal	-3	no	6.388	8.656	EPSD	GDSC	4.810	Up-regulation
CAMK_CAMK2_CAMK2A_ST	Q9Y496	KIF3A	Q9UQM7	CAMK2A	T672	R671*	671	Missense	proximal	-1	no	7.746	7.384	EPSD	GDSC	4.810	Down-regulation
CAMK_CAMK2_CAMK2A_ST	Q9Y4D2	DAGLA	Q9UQM7	CAMK2A	S743	L742P	742	Missense	proximal	-1	no	5.894	5.918	EPSD	GDSC;CCLE	4.810	Up-regulation
CAMK_CAMK2_CAMK2A_ST	Q9Y4D2	DAGLA	Q9UQM7	CAMK2A	S743	A750V	750	Missense	distal	7	no	5.894	5.923	EPSD	GDSC	4.810	Up-regulation
CAMK_CAMK2_CAMK2A_ST	Q9Y4D2	DAGLA	Q9UQM7	CAMK2A	S798	R804Q	804	Missense	distal	6	no	6.335	6.341	EPSD	GDSC;CCLE	4.810	Up-regulation
CAMK_CAMK2_CAMK2A_ST	Q9Y4D2	DAGLA	Q9UQM7	CAMK2A	S850	P855S	855	Missense	distal	5	no	5.879	6.109	EPSD	GDSC;CCLE	4.810	Up-regulation
CAMK_CAMK2_CAMK2A_ST	Q9Y4D2	DAGLA	Q9UQM7	CAMK2A	S954	A947V	947	Missense	distal	-7	no	4.938	5.378	EPSD	GDSC;CCLE	4.810	Up-regulation
CAMK_CAMK2_CAMK2A_ST	Q9BXL7	CARD11	Q9UQM7	CAMK2A	S520	Q523E	523	Missense	distal	3	no	5.861	6.069	EPSD	GDSC;CCLE	4.810	Up-regulation
CAMK_CAMK2_CAMK2A_ST	Q9BXL7	CARD11	Q9UQM7	CAMK2A	S558	R557H	557	Missense	proximal	-1	no	6.946	7.092	EPSD	GDSC	4.810	Up-regulation
CAMK_CAMK2_CAMK2A_ST	Q9BXL7	CARD11	Q9UQM7	CAMK2A	S618	H617R	617	Missense	proximal	-1	no	5.235	5.090	EPSD	GDSC;CCLE	4.810	Down-regulation
CAMK_CAMK2_CAMK2A_ST	Q9BXL7	CARD11	Q9UQM7	CAMK2A	S620	H617R	617	Missense	distal	-3	no	2.763	8.261	EPSD	GDSC;CCLE	4.810	Gain
CAMK_CAMK2_CAMK2A_ST	Q9BXL7	CARD11	Q9UQM7	CAMK2A	S644	K642N	642	Missense	proximal	-2	no	8.796	8.698	EPSD	GDSC;CCLE	4.810	Down-regulation
CAMK_CAMK2_CAMK2A_ST	Q9BXL7	CARD11	Q9UQM7	CAMK2A	S923	G928R	928	Missense	distal	5	no	6.853	6.896	EPSD	GDSC	4.810	Up-regulation
CAMK_CAMK2_CAMK2A_ST	Q9BXL7	CARD11	Q9UQM7	CAMK2A	S923	S923L	923	Missense	central	0	yes	6.853	0.000	EPSD	GDSC;CCLE	4.810	Loss
CAMK_CAMK2_CAMK2A_ST	Q01970	PLCB3	Q9UQM7	CAMK2A	S537	G542S	542	Missense	distal	5	no	4.634	4.817	PhosphoSitePlus	GDSC;CCLE	4.810	Gain
CAMK_CAMK2_CAMK2A_ST	Q01970	PLCB3	Q9UQM7	CAMK2A	S814	A815V	815	Missense	proximal	1	no	4.771	5.122	EPSD	GDSC;CCLE	4.810	Gain
CAMK_CAMK2_CAMK2A_ST	Q01970	PLCB3	Q9UQM7	CAMK2A	S814	R817H	817	Missense	distal	3	no	4.771	4.825	EPSD	GDSC;CCLE	4.810	Gain
CAMK_CAMK2_CAMK2A_ST	Q01970	PLCB3	Q9UQM7	CAMK2A	S1105	R1102C	1102	Missense	distal	-3	no	9.060	3.480	EPSD	GDSC;CCLE	4.810	Loss
CAMK_CAMK2_CAMK2A_ST	P16070	CD44	Q9UQM7	CAMK2A	S184	T189S	189	Missense	distal	5	no	4.795	4.956	EPSD	GDSC;CCLE	4.810	Gain
CAMK_CAMK2_CAMK2A_ST	P16070	CD44	Q9UQM7	CAMK2A	S291	S293Y	293	Missense	proximal	2	no	8.268	6.532	EPSD	GDSC;CCLE	4.810	Down-regulation
CAMK_CAMK2_CAMK2A_ST	P16070	CD44	Q9UQM7	CAMK2A	S420	R413P	413	Missense	distal	-7	no	5.968	6.129	EPSD	GDSC;CCLE	4.810	Up-regulation
CAMK_CAMK2_CAMK2A_ST	P16070	CD44	Q9UQM7	CAMK2A	S697	A703T	703	Missense	distal	6	no	5.717	5.627	EPSD	GDSC;CCLE	4.810	Down-regulation
CAMK_CAMK2_CAMK2A_ST	P16070	CD44	Q9UQM7	CAMK2A	S706	A703T	703	Missense	distal	-3	no	5.701	5.064	PhosphoSitePlus	GDSC;CCLE	4.810	Down-regulation
CAMK_CAMK2_CAMK2A_ST	P16070	CD44	Q9UQM7	CAMK2A	S706	M709R	709	Missense	distal	3	no	5.701	5.787	PhosphoSitePlus	GDSC;CCLE	4.810	Up-regulation
CAMK_CAMK2_CAMK2A_ST	P16070	CD44	Q9UQM7	CAMK2A	S717	S717L	717	Missense	central	0	yes	6.559	0.000	EPSD	GDSC	4.810	Loss
CAMK_CAMK2_CAMK2A_ST	P16070	CD44	Q9UQM7	CAMK2A	S718	S717L	717	Missense	proximal	-1	no	5.165	4.955	EPSD	GDSC	4.810	Down-regulation
CAMK_CAMK2_CAMK2A_ST	Q14674	ESPL1	Q9UQM7	CAMK2A	S1433	V1440I	1440	Missense	distal	7	no	5.412	5.527	EPSD	GDSC;CCLE	4.810	Up-regulation
CAMK_CAMK2_CAMK2A_ST	Q14674	ESPL1	Q9UQM7	CAMK2A	S1455	G1453D	1453	Missense	proximal	-2	no	5.460	5.336	EPSD	GDSC;CCLE	4.810	Down-regulation
CAMK_CAMK2_CAMK2A_ST	Q14674	ESPL1	Q9UQM7	CAMK2A	S1820	A1816S	1816	Missense	distal	-4	no	5.228	5.219	EPSD	GDSC	4.810	Down-regulation
CAMK_CAMK2_CAMK2A_ST	O95180	CACNA1H	Q9UQM7	CAMK2A	S1587	T1588N	1588	Missense	proximal	1	no	5.655	5.230	EPSD	GDSC;CCLE	4.810	Down-regulation
CAMK_CAMK2_CAMK2A_ST	O95180	CACNA1H	Q9UQM7	CAMK2A	S1587	S1587G	1587	Missense	central	0	yes	5.655	0.000	EPSD	GDSC	4.810	Loss
CAMK_CAMK2_CAMK2A_ST	O95180	CACNA1H	Q9UQM7	CAMK2A	S1587	A1594S	1594	Missense	distal	7	no	5.655	5.609	EPSD	GDSC	4.810	Down-regulation
CAMK_CAMK2_CAMK2A_ST	O95180	CACNA1H	Q9UQM7	CAMK2A	S1587	A1594V	1594	Missense	distal	7	no	5.655	5.684	EPSD	GDSC	4.810	Up-regulation
CAMK_CAMK2_CAMK2A_ST	O95180	CACNA1H	Q9UQM7	CAMK2A	S1920	K1918N	1918	Missense	proximal	-2	no	5.199	5.101	EPSD	GDSC;CCLE	4.810	Down-regulation
CAMK_CAMK2_CAMK2A_ST	O95180	CACNA1H	Q9UQM7	CAMK2A	S1926	M1933T	1933	Missense	distal	7	no	8.009	8.001	EPSD	GDSC;CCLE	4.810	Down-regulation
CAMK_CAMK2_CAMK2A_ST	O95180	CACNA1H	Q9UQM7	CAMK2A	S2137	A2140T	2140	Missense	distal	3	no	8.990	8.755	EPSD	GDSC	4.810	Down-regulation
CAMK_CAMK2_CAMK2A_ST	O95180	CACNA1H	Q9UQM7	CAMK2A	S2137	F2143L	2143	Missense	distal	6	no	8.990	9.032	EPSD	GDSC;CCLE	4.810	Up-regulation
CAMK_CAMK2_CAMK2A_ST	Q14457	BECN1	Q9UQM7	CAMK2A	S15	Q13*	13	Missense	proximal	-2	no	5.837	5.304	EPSD	GDSC	4.810	Down-regulation
CAMK_CAMK2_CAMK2A_ST	Q14457	BECN1	Q9UQM7	CAMK2A	S15	S10N	10	Missense	distal	-5	no	5.837	5.900	EPSD	GDSC;CCLE	4.810	Up-regulation
CAMK_CAMK2_CAMK2A_ST	Q13224	GRIN2B	Q9UQM7	CAMK2A	S930	R926*	926	Missense	distal	-4	no	6.367	5.918	EPSD	GDSC	4.810	Down-regulation
CAMK_CAMK2_CAMK2A_ST	P42261	GRIA1	Q9UQM7	CAMK2A	T858	S863I	863	Missense	distal	5	no	6.756	6.487	EPSD	GDSC;CCLE	4.810	Down-regulation
CAMK_CAMK2_CAMK2A_ST	P42261	GRIA1	Q9UQM7	CAMK2A	T858	T858P	858	Missense	central	0	yes	6.756	0.000	EPSD	GDSC	4.810	Loss
CAMK_CAMK2_CAMK2A_ST	Q04760	GLO1	Q9UQM7	CAMK2A	S45	P42L	42	Missense	distal	-3	no	5.182	4.978	EPSD	GDSC;CCLE	4.810	Down-regulation
CAMK_CAMK2_CAMK2A_ST	Q04760	GLO1	Q9UQM7	CAMK2A	S45	R38*	38	Missense	distal	-7	no	5.182	5.677	EPSD	GDSC	4.810	Up-regulation
CAMK_CAMK2_CAMK2A_ST	P10636	MAPT	Q9UQM7	CAMK2A	S171	D177V	177	Missense	distal	6	no	5.997	5.845	EPSD	GDSC	4.810	Down-regulation
CAMK_CAMK2_CAMK2A_ST	P10636	MAPT	Q9UQM7	CAMK2A	S214	V218G	218	Missense	distal	4	no	8.732	8.742	EPSD	GDSC	4.810	Up-regulation
CAMK_CAMK2_CAMK2A_ST	P10636	MAPT	Q9UQM7	CAMK2A	S341	P340L	340	Missense	proximal	-1	no	7.485	7.461	EPSD	GDSC;CCLE	4.810	Down-regulation
CAMK_CAMK2_CAMK2A_ST	P10636	MAPT	Q9UQM7	CAMK2A	S341	G339S	339	Missense	proximal	-2	no	7.485	7.643	EPSD	GDSC;CCLE	4.810	Up-regulation
CAMK_CAMK2_CAMK2A_ST	P10636	MAPT	Q9UQM7	CAMK2A	T470	A475V	475	Missense	distal	5	no	5.245	5.027	EPSD	GDSC;CCLE	4.810	Down-regulation
CAMK_CAMK2_CAMK2A_ST	P10636	MAPT	Q9UQM7	CAMK2A	S637	V635I	635	Missense	proximal	-2	no	4.621	4.863	EPSD	GDSC	4.810	Gain
CAMK_CAMK2_CAMK2A_ST	P10636	MAPT	Q9UQM7	CAMK2A	S733	S739C	739	Missense	distal	6	no	7.015	6.852	EPSD	GDSC	4.810	Down-regulation
CAMK_CAMK2_CAMK2A_ST	P26678	PLN	Q9UQM7	CAMK2A	S16	P21L	21	Missense	distal	5	no	9.816	9.757	EPSD	GDSC;CCLE	4.810	Down-regulation
CAMK_CAMK2_CAMK2A_ST	P26678	PLN	Q9UQM7	CAMK2A	T17	P21L	21	Missense	distal	4	no	9.546	9.509	PhosphoSitePlus	GDSC;CCLE	4.810	Down-regulation
Other_Aur_AURKA_ST	O43379	WDR62	O14965	AURKA	S979	P983R	983	Missense	distal	4	no	39.825	39.347	EPSD	GDSC;CCLE	39.062	Down-regulation
Other_Aur_AURKA_ST	O43379	WDR62	O14965	AURKA	S980	P983R	983	Missense	distal	3	no	42.627	42.213	EPSD	GDSC;CCLE	39.062	Down-regulation
Other_Aur_AURKA_ST	Q9UNN5	FAF1	O14965	AURKA	S212	Y207H	207	Missense	distal	-5	no	43.863	43.800	EPSD	GDSC;CCLE	39.062	Down-regulation
Other_Aur_AURKA_ST	Q9UNN5	FAF1	O14965	AURKA	S269	R275W	275	Missense	distal	6	no	39.220	39.429	EPSD	GDSC	39.062	Up-regulation
Other_Aur_AURKA_ST	Q9UNN5	FAF1	O14965	AURKA	S270	R275W	275	Missense	distal	5	no	41.982	42.981	EPSD	GDSC	39.062	Up-regulation
Other_Aur_AURKA_ST	O14965	AURKA	O14965	AURKA	S83	V84A	84	Missense	proximal	1	no	43.988	44.168	EPSD;PhosphoSitePlus	GDSC	39.062	Up-regulation
Other_Aur_AURKA_ST	O14965	AURKA	O14965	AURKA	S104	P110H	110	Missense	distal	6	no	48.023	48.064	EPSD;PhosphoSitePlus	GDSC;CCLE	39.062	Up-regulation
Other_Aur_AURKA_ST	Q14980	NUMA1	O14965	AURKA	S271	N265K	265	Missense	distal	-6	no	41.767	36.608	EPSD	GDSC;CCLE	39.062	Loss
Other_Aur_AURKA_ST	Q14980	NUMA1	O14965	AURKA	S395	P402L	402	Missense	distal	7	no	47.790	47.873	EPSD	GDSC	39.062	Up-regulation
Other_Aur_AURKA_ST	Q14980	NUMA1	O14965	AURKA	S633	D632N	632	Missense	proximal	-1	no	48.213	45.051	EPSD	GDSC	39.062	Down-regulation
Other_Aur_AURKA_ST	Q14980	NUMA1	O14965	AURKA	S633	A627T	627	Missense	distal	-6	no	48.213	47.992	EPSD	GDSC;CCLE	39.062	Down-regulation
Other_Aur_AURKA_ST	Q14980	NUMA1	O14965	AURKA	S633	T636I	636	Missense	distal	3	no	48.213	51.230	EPSD	GDSC;CCLE	39.062	Up-regulation
Other_Aur_AURKA_ST	Q14980	NUMA1	O14965	AURKA	S717	E721K	721	Missense	distal	4	no	39.501	39.485	EPSD	GDSC;CCLE	39.062	Down-regulation
Other_Aur_AURKA_ST	Q14980	NUMA1	O14965	AURKA	S717	R724G	724	Missense	distal	7	no	39.501	39.638	EPSD	GDSC	39.062	Up-regulation
Other_Aur_AURKA_ST	Q14980	NUMA1	O14965	AURKA	S1203	S1203N	1203	Missense	central	0	yes	44.554	0.000	EPSD	GDSC;CCLE	39.062	Loss
Other_Aur_AURKA_ST	Q14980	NUMA1	O14965	AURKA	T1804	G1801S	1801	Missense	distal	-3	no	44.896	43.611	EPSD;PhosphoSitePlus	GDSC	39.062	Down-regulation
Other_Aur_AURKA_ST	Q14980	NUMA1	O14965	AURKA	S1830	Y1836S	1836	Missense	distal	6	no	41.852	41.922	EPSD	GDSC;CCLE	39.062	Up-regulation
Other_Aur_AURKA_ST	Q14980	NUMA1	O14965	AURKA	T1851	S1852T	1852	Missense	proximal	1	no	41.206	44.455	EPSD	GDSC;CCLE	39.062	Up-regulation
Other_Aur_AURKA_ST	Q14980	NUMA1	O14965	AURKA	S1853	S1852T	1852	Missense	proximal	-1	no	38.087	39.789	EPSD	GDSC;CCLE	39.062	Gain
Other_Aur_AURKA_ST	Q14980	NUMA1	O14965	AURKA	T1879	R1877H	1877	Missense	proximal	-2	no	45.315	38.077	EPSD	GDSC;CCLE	39.062	Loss
Other_Aur_AURKA_ST	Q14980	NUMA1	O14965	AURKA	S1883	R1877H	1877	Missense	distal	-6	no	42.852	40.682	EPSD	GDSC;CCLE	39.062	Down-regulation
Other_Aur_AURKA_ST	Q14980	NUMA1	O14965	AURKA	S2047	M2048I	2048	Missense	proximal	1	no	49.503	46.940	EPSD;PhosphoSitePlus	GDSC	39.062	Down-regulation
Other_Aur_AURKA_ST	Q14980	NUMA1	O14965	AURKA	T2080	S2077P	2077	Missense	distal	-3	no	40.306	38.127	EPSD	GDSC	39.062	Loss
Other_Aur_AURKA_ST	Q14980	NUMA1	O14965	AURKA	T2080	S2082R	2082	Missense	proximal	2	no	40.306	39.101	EPSD	GDSC	39.062	Down-regulation
Other_Aur_AURKA_ST	Q14980	NUMA1	O14965	AURKA	T2080	S2077Y	2077	Missense	distal	-3	no	40.306	37.170	EPSD	GDSC	39.062	Loss
Other_Aur_AURKA_ST	Q14980	NUMA1	O14965	AURKA	T2084	S2077P	2077	Missense	distal	-7	no	43.308	45.168	EPSD;PhosphoSitePlus	GDSC	39.062	Up-regulation
Other_Aur_AURKA_ST	Q14980	NUMA1	O14965	AURKA	T2084	S2082R	2082	Missense	proximal	-2	no	43.308	56.467	EPSD;PhosphoSitePlus	GDSC	39.062	Up-regulation
Other_Aur_AURKA_ST	Q14980	NUMA1	O14965	AURKA	T2084	S2077Y	2077	Missense	distal	-7	no	43.308	43.495	EPSD;PhosphoSitePlus	GDSC	39.062	Up-regulation
Other_Aur_AURKA_ST	Q14980	NUMA1	O14965	AURKA	T2084	A2091G	2091	Missense	distal	7	no	43.308	43.481	EPSD;PhosphoSitePlus	GDSC	39.062	Up-regulation
Other_Aur_AURKA_ST	Q96R06	SPAG5	O14965	AURKA	S157	T155K	155	Missense	proximal	-2	no	31.940	44.650	EPSD	GDSC	39.062	Gain
Other_Aur_AURKA_ST	Q96R06	SPAG5	O14965	AURKA	S217	C216W	216	Missense	proximal	-1	no	45.045	48.936	EPSD	GDSC	39.062	Up-regulation
Other_Aur_AURKA_ST	Q96R06	SPAG5	O14965	AURKA	S362	N358Y	358	Missense	distal	-4	no	40.293	39.796	EPSD	GDSC;CCLE	39.062	Down-regulation
Other_Aur_AURKA_ST	Q96R06	SPAG5	O14965	AURKA	S362	R360H	360	Missense	proximal	-2	no	40.293	33.055	EPSD	GDSC	39.062	Loss
Other_Aur_AURKA_ST	Q96R06	SPAG5	O14965	AURKA	S367	R360H	360	Missense	distal	-7	no	44.908	43.432	EPSD	GDSC	39.062	Down-regulation
Other_Aur_AURKA_ST	Q14203	DCTN1	O14965	AURKA	S31	R32L	32	Missense	proximal	1	no	37.875	40.305	EPSD	GDSC;CCLE	39.062	Gain
Other_Aur_AURKA_ST	Q14203	DCTN1	O14965	AURKA	T1001	E999Q	999	Missense	proximal	-2	no	29.809	39.817	EPSD	GDSC;CCLE	39.062	Gain
Other_Aur_AURKA_ST	P00352	ALDH1A1	O14965	AURKA	S207	L200F	200	Missense	distal	-7	no	53.109	52.753	EPSD	GDSC;CCLE	39.062	Down-regulation
Other_Aur_AURKA_ST	P46937	YAP1	O14965	AURKA	S94	P98L	98	Missense	distal	4	no	40.709	40.856	EPSD	GDSC;CCLE	39.062	Up-regulation
Other_Aur_AURKA_ST	P46937	YAP1	O14965	AURKA	S163	R161*	161	Missense	proximal	-2	no	46.607	-30.011	EPSD	GDSC	39.062	Loss
Other_Aur_AURKA_ST	P46937	YAP1	O14965	AURKA	S164	R161*	161	Missense	distal	-3	no	45.881	2.651	EPSD	GDSC	39.062	Loss
Other_Aur_AURKA_ST	P46937	YAP1	O14965	AURKA	S350	A347S	347	Missense	distal	-3	no	37.682	39.095	EPSD	GDSC	39.062	Gain
Other_Aur_AURKA_ST	P46937	YAP1	O14965	AURKA	S382	D383A	383	Missense	proximal	1	no	38.299	39.142	EPSD	GDSC;CCLE	39.062	Gain
Other_Aur_AURKA_ST	Q92974	ARHGEF2	O14965	AURKA	S142	R141H	141	Missense	proximal	-1	no	47.482	47.072	EPSD	GDSC	39.062	Down-regulation
Other_Aur_AURKA_ST	Q92974	ARHGEF2	O14965	AURKA	S143	R141H	141	Missense	proximal	-2	no	47.935	40.697	EPSD	GDSC	39.062	Down-regulation
Other_Aur_AURKA_ST	P38398	BRCA1	O14965	AURKA	S184	S186F	186	Missense	proximal	2	no	40.926	40.230	EPSD	GDSC;CCLE	39.062	Down-regulation
Other_Aur_AURKA_ST	P38398	BRCA1	O14965	AURKA	T509	L502*	502	Missense	distal	-7	no	43.947	37.628	EPSD	GDSC	39.062	Loss
Other_Aur_AURKA_ST	P38398	BRCA1	O14965	AURKA	S1580	P1579S	1579	Missense	proximal	-1	no	43.247	43.462	EPSD	GDSC;CCLE	39.062	Up-regulation
Other_Aur_AURKA_ST	P38398	BRCA1	O14965	AURKA	S1598	S1596A	1596	Missense	proximal	-2	no	38.883	40.403	EPSD	GDSC	39.062	Gain
Other_Aur_AURKA_ST	P12755	SKI	O14965	AURKA	S347	P346H	346	Missense	proximal	-1	no	40.452	40.246	EPSD	GDSC;CCLE	39.062	Down-regulation
Other_Aur_AURKA_ST	P12755	SKI	O14965	AURKA	S347	S347F	347	Missense	central	0	yes	40.452	0.000	EPSD	GDSC;CCLE	39.062	Loss
Other_Aur_AURKA_ST	P12755	SKI	O14965	AURKA	S377	Q374R	374	Missense	distal	-3	no	40.998	50.661	EPSD	GDSC;CCLE	39.062	Up-regulation
Other_Aur_AURKA_ST	P12755	SKI	O14965	AURKA	S404	R402G	402	Missense	proximal	-2	no	42.731	32.587	EPSD	GDSC;CCLE	39.062	Loss
Other_Aur_AURKA_ST	P12755	SKI	O14965	AURKA	T458	P462A	462	Missense	distal	4	no	42.601	42.687	EPSD	GDSC	39.062	Up-regulation
Other_Aur_AURKA_ST	Q9BQG0	MYBBP1A	O14965	AURKA	S514	E511G	511	Missense	distal	-3	no	35.144	39.315	EPSD	GDSC	39.062	Gain
Other_Aur_AURKA_ST	Q9BQG0	MYBBP1A	O14965	AURKA	S635	R634W	634	Missense	proximal	-1	no	38.280	41.955	EPSD	GDSC	39.062	Gain
Other_Aur_AURKA_ST	Q9BQG0	MYBBP1A	O14965	AURKA	S1241	T1239A	1239	Missense	proximal	-2	no	34.028	41.604	EPSD	GDSC;CCLE	39.062	Gain
Other_Aur_AURKA_ST	Q9BQG0	MYBBP1A	O14965	AURKA	S1303	R1297W	1297	Missense	distal	-6	no	51.884	37.733	PhosphoSitePlus	GDSC	39.062	Loss
Other_Aur_AURKA_ST	Q9HC77	CENPJ	O14965	AURKA	S529	R535W	535	Missense	distal	6	no	43.885	44.094	EPSD	GDSC;CCLE	39.062	Up-regulation
Other_Aur_AURKA_ST	Q9HC77	CENPJ	O14965	AURKA	S717	G724S	724	Missense	distal	7	no	41.443	41.323	EPSD	GDSC;CCLE	39.062	Down-regulation
Other_Aur_AURKA_ST	Q9BT25	HAUS8	O14965	AURKA	T97	D101N	101	Missense	distal	4	no	43.808	42.726	EPSD	GDSC;CCLE	39.062	Down-regulation
Other_Aur_AURKA_ST	Q8TEW0	PARD3	O14965	AURKA	S143	P137S	137	Missense	distal	-6	no	44.529	45.079	EPSD	GDSC;CCLE	39.062	Up-regulation
Other_Aur_AURKA_ST	Q8TEW0	PARD3	O14965	AURKA	S144	P137S	137	Missense	distal	-7	no	55.088	53.228	EPSD	GDSC;CCLE	39.062	Down-regulation
Other_Aur_AURKA_ST	Q8TEW0	PARD3	O14965	AURKA	S174	G178D	178	Missense	distal	4	no	44.902	44.832	EPSD	GDSC;CCLE	39.062	Down-regulation
Other_Aur_AURKA_ST	Q8TEW0	PARD3	O14965	AURKA	S174	T176A	176	Missense	proximal	2	no	44.902	46.162	EPSD	GDSC	39.062	Up-regulation
Other_Aur_AURKA_ST	Q8TEW0	PARD3	O14965	AURKA	S174	R172H	172	Missense	proximal	-2	no	44.902	37.664	EPSD	GDSC;CCLE	39.062	Loss
Other_Aur_AURKA_ST	Q8TEW0	PARD3	O14965	AURKA	T401	T401R	401	Missense	central	0	yes	39.537	0.000	EPSD	GDSC;CCLE	39.062	Loss
Other_Aur_AURKA_ST	Q8TEW0	PARD3	O14965	AURKA	S665	T661I	661	Missense	distal	-4	no	42.295	34.588	EPSD	GDSC;CCLE	39.062	Loss
Other_Aur_AURKA_ST	Q8TEW0	PARD3	O14965	AURKA	S892	E899K	899	Missense	distal	7	no	40.397	40.286	EPSD	GDSC;CCLE	39.062	Down-regulation
Other_Aur_AURKA_ST	Q8TEW0	PARD3	O14965	AURKA	T1176	D1172Y	1172	Missense	distal	-4	no	47.137	50.696	EPSD	GDSC;CCLE	39.062	Up-regulation
Other_Aur_AURKA_ST	Q8TEW0	PARD3	O14965	AURKA	S1222	R1226W	1226	Missense	distal	4	no	42.703	43.656	EPSD	GDSC	39.062	Up-regulation
Other_Aur_AURKA_ST	Q8NHV4	NEDD1	O14965	AURKA	S89	S94C	94	Missense	distal	5	no	40.660	41.657	EPSD	GDSC	39.062	Up-regulation
Other_Aur_AURKA_ST	P03372	ESR1	O14965	AURKA	S154	R151H	151	Missense	distal	-3	no	44.115	38.342	EPSD	GDSC	39.062	Loss
Other_Aur_AURKA_ST	P03372	ESR1	O14965	AURKA	S154	G160S	160	Missense	distal	6	no	44.115	44.117	EPSD	GDSC	39.062	Up-regulation
Other_Aur_AURKA_ST	P03372	ESR1	O14965	AURKA	S167	G160S	160	Missense	distal	-7	no	51.493	52.807	PhosphoSitePlus;EPSD	GDSC	39.062	Up-regulation
Other_Aur_AURKA_ST	P03372	ESR1	O14965	AURKA	S167	R164I	164	Missense	distal	-3	no	51.493	43.223	PhosphoSitePlus;EPSD	GDSC;CCLE	39.062	Down-regulation
Other_Aur_AURKA_ST	P03372	ESR1	O14965	AURKA	S236	R241L	241	Missense	distal	5	no	39.350	39.257	EPSD	GDSC;CCLE	39.062	Down-regulation
Other_Aur_AURKA_ST	P03372	ESR1	O14965	AURKA	S305	K299N	299	Missense	distal	-6	no	43.639	48.799	EPSD;PhosphoSitePlus	GDSC;CCLE	39.062	Up-regulation
Other_Aur_AURKA_ST	P03372	ESR1	O14965	AURKA	S305	I298V	298	Missense	distal	-7	no	43.639	44.180	EPSD;PhosphoSitePlus	GDSC	39.062	Up-regulation
Other_Aur_AURKA_ST	P06748	NPM1	O14965	AURKA	S137	A144T	144	Missense	distal	7	no	39.719	39.709	EPSD	GDSC;CCLE	39.062	Down-regulation
Other_Aur_AURKA_ST	P06748	NPM1	O14965	AURKA	S143	A144T	144	Missense	proximal	1	no	49.237	47.565	EPSD	GDSC;CCLE	39.062	Down-regulation
Other_Aur_AURKA_ST	P06748	NPM1	O14965	AURKA	S243	E245Q	245	Missense	proximal	2	no	45.603	45.942	EPSD	GDSC	39.062	Up-regulation
Other_Aur_AURKA_ST	Q15398	DLGAP5	O14965	AURKA	T66	V61I	61	Missense	distal	-5	no	49.713	49.716	EPSD	GDSC	39.062	Up-regulation
Other_Aur_AURKA_ST	Q15398	DLGAP5	O14965	AURKA	S757	M752I	752	Missense	distal	-5	no	43.830	43.810	EPSD;PhosphoSitePlus	GDSC;CCLE	39.062	Down-regulation
Other_Aur_AURKA_ST	Q13158	FADD	O14965	AURKA	S69	R64H	64	Missense	distal	-5	no	42.411	42.355	EPSD	GDSC;CCLE	39.062	Down-regulation
Other_Aur_AURKA_ST	Q13158	FADD	O14965	AURKA	S69	H73N	73	Missense	distal	4	no	42.411	41.398	EPSD	GDSC;CCLE	39.062	Down-regulation
Other_Aur_AURKA_ST	Q13158	FADD	O14965	AURKA	S69	L66P	66	Missense	distal	-3	no	42.411	41.268	EPSD	GDSC;CCLE	39.062	Down-regulation
Other_Aur_AURKA_ST	Q13158	FADD	O14965	AURKA	S69	L75V	75	Missense	distal	6	no	42.411	42.386	EPSD	GDSC;CCLE	39.062	Down-regulation
Other_Aur_AURKA_ST	Q9NRM7	LATS2	O14965	AURKA	S83	A76T	76	Missense	distal	-7	no	49.494	49.036	PhosphoSitePlus;EPSD	GDSC;CCLE	39.062	Down-regulation
Other_Aur_AURKA_ST	Q9NRM7	LATS2	O14965	AURKA	S380	G385S	385	Missense	distal	5	no	70.275	70.174	EPSD;PhosphoSitePlus	GDSC	39.062	Down-regulation
Other_Aur_AURKA_ST	Q9NRM7	LATS2	O14965	AURKA	S380	T374P	374	Missense	distal	-6	no	70.275	69.730	EPSD;PhosphoSitePlus	GDSC	39.062	Down-regulation
Other_Aur_AURKA_ST	Q9NRM7	LATS2	O14965	AURKA	S835	W842L	842	Missense	distal	7	no	49.319	49.105	EPSD	GDSC;CCLE	39.062	Down-regulation
Other_Aur_AURKA_ST	O14777	NDC80	O14965	AURKA	S55	K53R	53	Missense	proximal	-2	no	48.968	55.472	EPSD;PhosphoSitePlus	GDSC;CCLE	39.062	Up-regulation
Other_Aur_AURKA_ST	Q99708	RBBP8	O14965	AURKA	T361	G354R	354	Missense	distal	-7	no	39.739	41.626	EPSD	GDSC;CCLE	39.062	Up-regulation
Other_Aur_AURKA_ST	Q99708	RBBP8	O14965	AURKA	T361	K357N	357	Missense	distal	-4	no	39.739	39.382	EPSD	GDSC	39.062	Down-regulation
Other_Aur_AURKA_ST	Q99708	RBBP8	O14965	AURKA	T596	E597Q	597	Missense	proximal	1	no	37.177	39.427	EPSD	GDSC;CCLE	39.062	Gain
Other_Aur_AURKA_ST	Q99708	RBBP8	O14965	AURKA	S743	A741V	741	Missense	proximal	-2	no	42.256	42.854	EPSD	GDSC;CCLE	39.062	Up-regulation
Other_Aur_AURKA_ST	Q99708	RBBP8	O14965	AURKA	S743	E737G	737	Missense	distal	-6	no	42.256	42.633	EPSD	GDSC;CCLE	39.062	Up-regulation
Other_Aur_AURKA_ST	Q49MG5	MAP9	O14965	AURKA	S180	R179K	179	Missense	proximal	-1	no	41.687	41.339	EPSD	GDSC;CCLE	39.062	Down-regulation
Other_Aur_AURKA_ST	Q49MG5	MAP9	O14965	AURKA	S247	L252I	252	Missense	distal	5	no	37.080	39.166	EPSD	GDSC;CCLE	39.062	Gain
Other_Aur_AURKA_ST	Q49MG5	MAP9	O14965	AURKA	S305	D311G	311	Missense	distal	6	no	46.356	46.205	EPSD;PhosphoSitePlus	GDSC;CCLE	39.062	Down-regulation
Other_Aur_AURKA_ST	Q49MG5	MAP9	O14965	AURKA	S363	S363P	363	Missense	central	0	yes	40.835	0.000	EPSD	GDSC	39.062	Loss
Other_Aur_AURKA_ST	Q49MG5	MAP9	O14965	AURKA	S370	S363P	363	Missense	distal	-7	no	39.850	41.710	EPSD	GDSC	39.062	Up-regulation
Other_Aur_AURKA_ST	Q49MG5	MAP9	O14965	AURKA	T377	S378Y	378	Missense	proximal	1	no	39.173	43.250	EPSD	GDSC	39.062	Up-regulation
Other_Aur_AURKA_ST	Q49MG5	MAP9	O14965	AURKA	T377	L381M	381	Missense	distal	4	no	39.173	39.958	EPSD	GDSC	39.062	Up-regulation
Other_Aur_AURKA_ST	Q49MG5	MAP9	O14965	AURKA	S385	S378Y	378	Missense	distal	-7	no	42.090	42.277	EPSD	GDSC	39.062	Up-regulation
Other_Aur_AURKA_ST	Q49MG5	MAP9	O14965	AURKA	S385	L381M	381	Missense	distal	-4	no	42.090	42.033	EPSD	GDSC	39.062	Down-regulation
Other_Aur_AURKA_ST	Q96EB6	SIRT1	O14965	AURKA	S172	T177I	177	Missense	distal	5	no	43.161	43.671	EPSD	GDSC;CCLE	39.062	Up-regulation
Other_Aur_AURKA_ST	O43521	BCL2L11	O14965	AURKA	S90	G95E	95	Missense	distal	5	no	41.931	41.837	EPSD	GDSC;CCLE	39.062	Down-regulation
Other_Aur_AURKA_ST	O43521	BCL2L11	O14965	AURKA	S93	G95E	95	Missense	proximal	2	no	48.846	49.136	EPSD;PhosphoSitePlus	GDSC;CCLE	39.062	Up-regulation
Other_Aur_AURKA_ST	O43521	BCL2L11	O14965	AURKA	S94	G95E	95	Missense	proximal	1	no	49.381	48.842	EPSD;PhosphoSitePlus	GDSC;CCLE	39.062	Down-regulation
Other_Aur_AURKA_ST	O43521	BCL2L11	O14965	AURKA	S98	G95E	95	Missense	distal	-3	no	47.342	43.171	PhosphoSitePlus;EPSD	GDSC;CCLE	39.062	Down-regulation
Other_Aur_AURKA_ST	O43521	BCL2L11	O14965	AURKA	S113	A106P	106	Missense	distal	-7	no	40.152	42.127	EPSD	GDSC;CCLE	39.062	Up-regulation
Other_Aur_AURKA_ST	Q14511	NEDD9	O14965	AURKA	T126	V120I	120	Missense	distal	-6	no	40.028	33.246	EPSD	GDSC;CCLE	39.062	Loss
Other_Aur_AURKA_ST	Q14511	NEDD9	O14965	AURKA	T126	G123D	123	Missense	distal	-3	no	40.028	34.731	EPSD	GDSC;CCLE	39.062	Loss
Other_Aur_AURKA_ST	Q14511	NEDD9	O14965	AURKA	S296	S296N	296	Missense	central	0	yes	48.185	0.000	PhosphoSitePlus	GDSC;CCLE	39.062	Loss
Other_Aur_AURKA_ST	Q14511	NEDD9	O14965	AURKA	S296	P289L	289	Missense	distal	-7	no	48.185	46.512	PhosphoSitePlus	GDSC	39.062	Down-regulation
Other_Aur_AURKA_ST	Q9ULW0	TPX2	O14965	AURKA	S218	E216A	216	Missense	proximal	-2	no	32.268	41.276	EPSD	GDSC;CCLE	39.062	Gain
Other_Aur_AURKA_ST	Q9ULW0	TPX2	O14965	AURKA	S358	C364F	364	Missense	distal	6	no	41.277	41.611	EPSD	GDSC;CCLE	39.062	Up-regulation
Other_Aur_AURKA_ST	Q9ULW0	TPX2	O14965	AURKA	T499	M497I	497	Missense	proximal	-2	no	40.933	39.734	EPSD	GDSC;CCLE	39.062	Down-regulation
Other_Aur_AURKA_ST	Q9ULW0	TPX2	O14965	AURKA	T588	K583N	583	Missense	distal	-5	no	45.458	45.527	EPSD	GDSC;CCLE	39.062	Up-regulation
Other_Aur_AURKA_ST	Q9UPY8	MAPRE3	O14965	AURKA	S176	A179S	179	Missense	distal	3	no	52.054	53.509	PhosphoSitePlus	GDSC;CCLE	39.062	Up-regulation
Other_Aur_AURKA_ST	P04637	TP53	O14965	AURKA	S106	K101*	101	Missense	distal	-5	no	42.716	42.850	PhosphoSitePlus;EPSD	GDSC	39.062	Up-regulation
Other_Aur_AURKA_ST	P04637	TP53	O14965	AURKA	S106	Q100*	100	Missense	distal	-6	no	42.716	27.218	PhosphoSitePlus;EPSD	GDSC	39.062	Loss
Other_Aur_AURKA_ST	P04637	TP53	O14965	AURKA	S106	Y107*	107	Missense	proximal	1	no	42.716	18.458	PhosphoSitePlus;EPSD	GDSC	39.062	Loss
Other_Aur_AURKA_ST	P04637	TP53	O14965	AURKA	S183	S183*	183	Missense	central	0	yes	41.241	0.000	EPSD	GDSC	39.062	Loss
Other_Aur_AURKA_ST	P04637	TP53	O14965	AURKA	S183	E180*	180	Missense	distal	-3	no	41.241	7.375	EPSD	GDSC	39.062	Loss
Other_Aur_AURKA_ST	P04637	TP53	O14965	AURKA	S215	R213*	213	Missense	proximal	-2	no	49.444	-27.174	EPSD;PhosphoSitePlus	GDSC	39.062	Loss
Other_Aur_AURKA_ST	P04637	TP53	O14965	AURKA	S215	R209*	209	Missense	distal	-6	no	49.444	33.080	EPSD;PhosphoSitePlus	GDSC	39.062	Loss
Other_Aur_AURKA_ST	P04637	TP53	O14965	AURKA	S269	E271*	271	Missense	proximal	2	no	39.770	40.795	EPSD	GDSC	39.062	Up-regulation
Other_Aur_AURKA_ST	P04637	TP53	O14965	AURKA	S313	R306*	306	Missense	distal	-7	no	41.824	35.119	EPSD	GDSC	39.062	Loss
Other_Aur_AURKA_ST	P04637	TP53	O14965	AURKA	S313	Q317*	317	Missense	distal	4	no	41.824	43.738	EPSD	GDSC	39.062	Up-regulation
Other_Aur_AURKA_ST	P04637	TP53	O14965	AURKA	S313	K319*	319	Missense	distal	6	no	41.824	42.231	EPSD	GDSC	39.062	Up-regulation
Other_Aur_AURKA_ST	P04637	TP53	O14965	AURKA	S315	Q317*	317	Missense	proximal	2	no	43.992	44.678	EPSD;PhosphoSitePlus	GDSC	39.062	Up-regulation
Other_Aur_AURKA_ST	P04637	TP53	O14965	AURKA	S315	K319*	319	Missense	distal	4	no	43.992	45.346	EPSD;PhosphoSitePlus	GDSC	39.062	Up-regulation
Other_Aur_AURKA_ST	Q13526	PIN1	O14965	AURKA	S105	D102E	102	Missense	distal	-3	no	38.090	39.216	EPSD	GDSC;CCLE	39.062	Gain
Other_Aur_AURKA_ST	Q8IX03	WWC1	O14965	AURKA	T912	K906E	906	Missense	distal	-6	no	41.443	40.260	EPSD	GDSC;CCLE	39.062	Down-regulation
Other_Aur_AURKA_ST	Q8IX03	WWC1	O14965	AURKA	T912	L919F	919	Missense	distal	7	no	41.443	41.492	EPSD	GDSC;CCLE	39.062	Up-regulation
Other_Aur_AURKA_ST	Q8IX03	WWC1	O14965	AURKA	S922	L919F	919	Missense	distal	-3	no	43.693	39.113	EPSD	GDSC;CCLE	39.062	Down-regulation
Other_Aur_AURKA_ST	Q8IX03	WWC1	O14965	AURKA	S922	R920Q	920	Missense	proximal	-2	no	43.693	33.054	EPSD	GDSC;CCLE	39.062	Loss
Other_Aur_AURKA_ST	Q8IX03	WWC1	O14965	AURKA	S945	R941Q	941	Missense	distal	-4	no	40.984	41.138	EPSD	GDSC	39.062	Up-regulation
Other_Aur_AURKA_ST	Q8IX03	WWC1	O14965	AURKA	S978	R972W	972	Missense	distal	-6	no	54.263	40.112	EPSD	GDSC;CCLE	39.062	Down-regulation
Other_Aur_AURKA_ST	Q8IX03	WWC1	O14965	AURKA	S978	I985V	985	Missense	distal	7	no	54.263	54.225	EPSD	GDSC;CCLE	39.062	Down-regulation
Other_Aur_AURKA_ST	P10275	AR	O14965	AURKA	S336	G334R	334	Missense	proximal	-2	no	39.251	49.394	EPSD	GDSC;CCLE	39.062	Up-regulation
Other_Aur_AURKA_ST	O15360	FANCA	O14965	AURKA	S1374	T1375A	1375	Missense	proximal	1	no	40.044	41.716	EPSD	GDSC;CCLE	39.062	Up-regulation
Other_Aur_AURKA_ST	P53667	LIMK1	O14965	AURKA	T261	H259R	259	Missense	proximal	-2	no	38.585	45.824	EPSD	GDSC	39.062	Gain
Other_Aur_AURKA_ST	P53667	LIMK1	O14965	AURKA	S337	P336L	336	Missense	proximal	-1	no	39.376	38.022	EPSD	GDSC	39.062	Loss
Other_Aur_AURKA_ST	P53667	LIMK1	O14965	AURKA	T508	R506C	506	Missense	proximal	-2	no	40.996	25.699	PhosphoSitePlus;EPSD	GDSC;CCLE	39.062	Loss
Other_Aur_AURKA_ST	Q9BXS6	NUSAP1	O14965	AURKA	S154	K161R	161	Missense	distal	7	no	40.925	40.969	EPSD	GDSC;CCLE	39.062	Up-regulation
Other_Aur_AURKA_ST	Q9BXS6	NUSAP1	O14965	AURKA	T166	K161R	161	Missense	distal	-5	no	40.083	40.108	EPSD	GDSC;CCLE	39.062	Up-regulation
Other_Aur_AURKA_ST	Q9BXS6	NUSAP1	O14965	AURKA	T166	G173E	173	Missense	distal	7	no	40.083	40.012	EPSD	GDSC	39.062	Down-regulation
Other_Aur_AURKA_ST	Q9BXS6	NUSAP1	O14965	AURKA	S296	P301S	301	Missense	distal	5	no	39.557	40.219	EPSD	GDSC;CCLE	39.062	Up-regulation
Other_Aur_AURKA_ST	Q9BXS6	NUSAP1	O14965	AURKA	S363	V357A	357	Missense	distal	-6	no	40.882	41.718	EPSD	GDSC	39.062	Up-regulation
Other_Aur_AURKA_ST	Q9BXS6	NUSAP1	O14965	AURKA	S363	Y370C	370	Missense	distal	7	no	40.882	40.824	EPSD	GDSC;CCLE	39.062	Down-regulation
Other_Aur_AURKA_ST	P49736	MCM2	O14965	AURKA	S32	T25A	25	Missense	distal	-7	no	38.758	39.216	EPSD	GDSC;CCLE	39.062	Gain
Other_Aur_AURKA_ST	P49736	MCM2	O14965	AURKA	T39	S40F	40	Missense	proximal	1	no	33.239	39.719	EPSD	GDSC;CCLE	39.062	Gain
Other_Aur_AURKA_ST	P49736	MCM2	O14965	AURKA	T158	E162K	162	Missense	distal	4	no	43.684	43.668	EPSD	GDSC;CCLE	39.062	Down-regulation
Other_Aur_AURKA_ST	P49736	MCM2	O14965	AURKA	S599	A603V	603	Missense	distal	4	no	42.613	42.320	EPSD	GDSC;CCLE	39.062	Down-regulation
Other_Aur_AURKA_ST	P49736	MCM2	O14965	AURKA	S809	K807R	807	Missense	proximal	-2	no	34.304	40.808	EPSD	GDSC	39.062	Gain
Other_Aur_AURKA_ST	Q9Y6A5	TACC3	O14965	AURKA	S34	R37G	37	Missense	distal	3	no	51.131	51.790	EPSD	GDSC;CCLE	39.062	Up-regulation
Other_Aur_AURKA_ST	Q9Y6A5	TACC3	O14965	AURKA	S39	R37G	37	Missense	proximal	-2	no	40.106	29.962	EPSD	GDSC;CCLE	39.062	Loss
Other_Aur_AURKA_ST	Q9Y6A5	TACC3	O14965	AURKA	T87	Q84*	84	Missense	distal	-3	no	47.660	14.093	EPSD	GDSC	39.062	Loss
Other_Aur_AURKA_ST	Q9Y6A5	TACC3	O14965	AURKA	S175	G172E	172	Missense	distal	-3	no	39.080	34.909	EPSD	GDSC;CCLE	39.062	Loss
Other_Aur_AURKA_ST	Q9Y6A5	TACC3	O14965	AURKA	S175	S175F	175	Missense	central	0	yes	39.080	0.000	EPSD	GDSC;CCLE	39.062	Loss
Other_Aur_AURKA_ST	Q9Y6A5	TACC3	O14965	AURKA	T196	D192N	192	Missense	distal	-4	no	41.851	45.908	EPSD	GDSC;CCLE	39.062	Up-regulation
Other_Aur_AURKA_ST	Q9Y6A5	TACC3	O14965	AURKA	T196	R193K	193	Missense	distal	-3	no	41.851	34.026	EPSD	GDSC;CCLE	39.062	Loss
Other_Aur_AURKA_ST	Q9Y6A5	TACC3	O14965	AURKA	S330	S331L	331	Missense	proximal	1	no	37.150	42.800	EPSD	GDSC;CCLE	39.062	Gain
Other_Aur_AURKA_ST	Q9Y6A5	TACC3	O14965	AURKA	S402	M396I	396	Missense	distal	-6	no	46.420	39.495	EPSD	GDSC;CCLE	39.062	Down-regulation
Other_Aur_AURKA_ST	Q9Y6A5	TACC3	O14965	AURKA	S570	V577M	577	Missense	distal	7	no	48.144	48.028	EPSD	GDSC	39.062	Down-regulation
Other_Aur_AURKA_ST	P30305	CDC25B	O14965	AURKA	T86	R93Q	93	Missense	distal	7	no	39.121	39.064	EPSD	GDSC;CCLE	39.062	Down-regulation
Other_Aur_AURKA_ST	P30305	CDC25B	O14965	AURKA	T86	S89T	89	Missense	distal	3	no	39.121	36.535	EPSD	GDSC;CCLE	39.062	Loss
Other_Aur_AURKA_ST	P30305	CDC25B	O14965	AURKA	S89	R93Q	93	Missense	distal	4	no	42.061	42.475	EPSD	GDSC;CCLE	39.062	Up-regulation
Other_Aur_AURKA_ST	P30305	CDC25B	O14965	AURKA	S178	E179K	179	Missense	proximal	1	no	47.032	49.056	EPSD	GDSC	39.062	Up-regulation
Other_Aur_AURKA_ST	P30305	CDC25B	O14965	AURKA	S182	E179K	179	Missense	distal	-3	no	42.157	43.696	EPSD	GDSC	39.062	Up-regulation
Other_Aur_AURKA_ST	P30305	CDC25B	O14965	AURKA	S375	R369C	369	Missense	distal	-6	no	39.179	32.131	EPSD	GDSC	39.062	Loss
Other_Aur_AURKA_ST	P30305	CDC25B	O14965	AURKA	S513	Y511H	511	Missense	proximal	-2	no	35.422	42.060	EPSD	GDSC	39.062	Gain
Atypical_GTF2F1_GTF2F1_ST	P35269	GTF2F1	P35269	GTF2F1	S442	K444N	444	Missense	proximal	2	no	2.096	2.296	EPSD	GDSC;CCLE	1.654	Up-regulation
Atypical_GTF2F1_GTF2F1_ST	P35269	GTF2F1	P35269	GTF2F1	T445	K444N	444	Missense	proximal	-1	no	2.314	2.251	EPSD	GDSC;CCLE	1.654	Down-regulation
Atypical_GTF2F1_GTF2F1_ST	P35269	GTF2F1	P35269	GTF2F1	T445	V452M	452	Missense	distal	7	no	2.314	2.307	EPSD	GDSC	1.654	Down-regulation
Atypical_GTF2F1_GTF2F1_ST	P13631	RARG	P35269	GTF2F1	S43	G50D	50	Missense	distal	7	no	3.549	3.568	EPSD	GDSC;CCLE	1.654	Up-regulation
AGC_NDR_LATS_LATS1_ST	Q9NQS7	INCENP	O95835	LATS1	S197	R194C	194	Missense	distal	-3	no	0.003	0.000	EPSD	GDSC	0.001	Loss
AGC_NDR_LATS_LATS1_ST	Q9NQS7	INCENP	O95835	LATS1	T199	R194C	194	Missense	distal	-5	no	0.001	0.000	EPSD	GDSC	0.001	Loss
AGC_NDR_LATS_LATS1_ST	Q9NQS7	INCENP	O95835	LATS1	T298	P293H	293	Missense	distal	-5	no	0.000	0.001	EPSD	GDSC;CCLE	0.001	Gain
AGC_NDR_LATS_LATS1_ST	Q9NQS7	INCENP	O95835	LATS1	S323	Q320H	320	Missense	distal	-3	no	0.000	0.001	EPSD	GDSC;CCLE	0.001	Gain
AGC_NDR_LATS_LATS1_ST	P46937	YAP1	O95835	LATS1	S164	R161*	161	Missense	distal	-3	no	0.005	0.002	EPSD;PhosphoSitePlus	GDSC	0.001	Down-regulation
AGC_NDR_LATS_LATS1_ST	P04049	RAF1	O95835	LATS1	S357	S352F	352	Missense	distal	-5	no	0.002	0.003	EPSD	GDSC;CCLE	0.001	Up-regulation
AGC_NDR_LATS_LATS1_ST	Q4VCS5	AMOT	O95835	LATS1	S264	H261N	261	Missense	distal	-3	no	0.001	0.000	EPSD	GDSC;CCLE	0.001	Loss
AGC_NDR_LATS_LATS1_ST	Q4VCS5	AMOT	O95835	LATS1	T709	T709A	709	Missense	central	0	yes	0.002	0.000	EPSD	GDSC;CCLE	0.001	Loss
AGC_NDR_LATS_LATS1_ST	Q4VCS5	AMOT	O95835	LATS1	S712	D707H	707	Missense	distal	-5	no	0.000	0.002	EPSD	GDSC	0.001	Gain
AGC_NDR_LATS_LATS1_ST	Q9GZV5	WWTR1	O95835	LATS1	S89	S89L	89	Missense	central	0	yes	0.005	0.000	PhosphoSitePlus	GDSC;CCLE	0.001	Loss
AGC_NDR_LATS_LATS1_ST	Q9GZV5	WWTR1	O95835	LATS1	S117	S117P	117	Missense	central	0	yes	0.005	0.000	EPSD	GDSC;CCLE	0.001	Loss
TK_PDGFR_PDGFRB_Y	P09619	PDGFRB	P09619	PDGFRB	Y686	I679N	679	Missense	distal	-7	no	43.099	45.266	EPSD	GDSC	43.065	Up-regulation
TK_PDGFR_PDGFRB_Y	P09619	PDGFRB	P09619	PDGFRB	Y751	M754T	754	Missense	distal	3	no	65.534	65.422	EPSD;PhosphoSitePlus	GDSC;CCLE	43.065	Down-regulation
TK_PDGFR_PDGFRB_Y	P09619	PDGFRB	P09619	PDGFRB	Y771	P774L	774	Missense	distal	3	no	66.784	66.677	EPSD;PhosphoSitePlus	GDSC;CCLE	43.065	Down-regulation
TK_PDGFR_PDGFRB_Y	P09619	PDGFRB	P09619	PDGFRB	Y775	P774L	774	Missense	proximal	-1	no	66.836	56.792	EPSD;PhosphoSitePlus	GDSC;CCLE	43.065	Down-regulation
TK_PDGFR_PDGFRB_Y	P09619	PDGFRB	P09619	PDGFRB	Y778	P774L	774	Missense	distal	-4	no	65.044	61.027	EPSD;PhosphoSitePlus	GDSC;CCLE	43.065	Down-regulation
TK_PDGFR_PDGFRB_Y	P16234	PDGFRA	P09619	PDGFRB	Y572	P577T	577	Missense	distal	5	no	50.468	32.291	EPSD	GDSC;CCLE	43.065	Loss
TK_PDGFR_PDGFRB_Y	P16234	PDGFRA	P09619	PDGFRB	Y574	P577T	577	Missense	distal	3	no	51.135	51.387	EPSD	GDSC;CCLE	43.065	Up-regulation
TK_PDGFR_PDGFRB_Y	P16234	PDGFRA	P09619	PDGFRB	Y582	P577T	577	Missense	distal	-5	no	57.225	57.689	EPSD	GDSC;CCLE	43.065	Up-regulation
TK_PDGFR_PDGFRB_Y	P16234	PDGFRA	P09619	PDGFRB	Y731	D730A	730	Missense	proximal	-1	no	55.105	55.477	EPSD	GDSC;CCLE	43.065	Up-regulation
TK_PDGFR_PDGFRB_Y	P16234	PDGFRA	P09619	PDGFRB	Y849	N848I	848	Missense	proximal	-1	no	72.976	65.239	EPSD	GDSC;CCLE	43.065	Down-regulation
TK_PDGFR_PDGFRB_Y	P42684	ABL2	P09619	PDGFRB	Y80	P73L	73	Missense	distal	-7	no	43.485	37.576	EPSD	GDSC	43.065	Loss
TK_PDGFR_PDGFRB_Y	Q13769	THOC5	P09619	PDGFRB	Y225	Q230R	230	Missense	distal	5	no	69.391	64.110	PhosphoSitePlus	GDSC;CCLE	43.065	Down-regulation
TK_PDGFR_PDGFRB_Y	P19174	PLCG1	P09619	PDGFRB	Y669	E667G	667	Missense	proximal	-2	no	39.835	44.997	EPSD	GDSC	43.065	Gain
TK_PDGFR_PDGFRB_Y	P19174	PLCG1	P09619	PDGFRB	Y833	R830*	830	Missense	distal	-3	no	46.545	40.833	EPSD	GDSC	43.065	Loss
TK_PDGFR_PDGFRB_Y	Q07912	TNK2	P09619	PDGFRB	Y518	P520L	520	Missense	proximal	2	no	49.239	40.536	EPSD	GDSC	43.065	Loss
TK_FGFR_FGFR4_Y	P22455	FGFR4	P22455	FGFR4	Y754	L757F	757	Missense	distal	3	no	4.451	4.483	PhosphoSitePlus	GDSC;CCLE	1.608	Up-regulation
CMGC_CDK_CDK7_CDK7_ST	P21127	CDK11B	P50613	CDK7	S38	R41W	41	Missense	distal	3	no	14.733	15.046	EPSD	GDSC;CCLE	13.598	Up-regulation
CMGC_CDK_CDK7_CDK7_ST	P21127	CDK11B	P50613	CDK7	T61	Y67C	67	Missense	distal	6	no	18.051	17.802	EPSD	GDSC;CCLE	13.598	Down-regulation
CMGC_CDK_CDK7_CDK7_ST	P21127	CDK11B	P50613	CDK7	T61	Y67*	67	Missense	distal	6	no	18.051	17.963	EPSD	GDSC	13.598	Down-regulation
CMGC_CDK_CDK7_CDK7_ST	P21127	CDK11B	P50613	CDK7	S92	R93Q	93	Missense	proximal	1	no	11.798	14.101	EPSD	GDSC	13.598	Gain
CMGC_CDK_CDK7_CDK7_ST	P49736	MCM2	P50613	CDK7	S27	T25A	25	Missense	proximal	-2	no	18.849	19.143	EPSD;PhosphoSitePlus	GDSC;CCLE	13.598	Up-regulation
CMGC_CDK_CDK7_CDK7_ST	P49736	MCM2	P50613	CDK7	S27	D22Y	22	Missense	distal	-5	no	18.849	18.803	EPSD;PhosphoSitePlus	GDSC;CCLE	13.598	Down-regulation
CMGC_CDK_CDK7_CDK7_ST	P49736	MCM2	P50613	CDK7	S40	S40F	40	Missense	central	0	yes	22.651	0.000	EPSD;PhosphoSitePlus	GDSC;CCLE	13.598	Loss
CMGC_CDK_CDK7_CDK7_ST	P49736	MCM2	P50613	CDK7	S40	R44G	44	Missense	distal	4	no	22.651	20.253	EPSD;PhosphoSitePlus	GDSC;CCLE	13.598	Down-regulation
CMGC_CDK_CDK7_CDK7_ST	P49736	MCM2	P50613	CDK7	S40	P42L	42	Missense	proximal	2	no	22.651	22.236	EPSD;PhosphoSitePlus	GDSC;CCLE	13.598	Down-regulation
CMGC_CDK_CDK7_CDK7_ST	P49736	MCM2	P50613	CDK7	S41	S40F	40	Missense	proximal	-1	no	22.804	22.195	EPSD;PhosphoSitePlus	GDSC;CCLE	13.598	Down-regulation
CMGC_CDK_CDK7_CDK7_ST	P49736	MCM2	P50613	CDK7	S41	R44G	44	Missense	distal	3	no	22.804	22.053	EPSD;PhosphoSitePlus	GDSC;CCLE	13.598	Down-regulation
CMGC_CDK_CDK7_CDK7_ST	P49736	MCM2	P50613	CDK7	S41	P42L	42	Missense	proximal	1	no	22.804	15.333	EPSD;PhosphoSitePlus	GDSC;CCLE	13.598	Down-regulation
CMGC_CDK_CDK7_CDK7_ST	P49736	MCM2	P50613	CDK7	S53	E52Q	52	Missense	proximal	-1	no	21.071	21.364	EPSD;PhosphoSitePlus	GDSC;CCLE	13.598	Up-regulation
CMGC_CDK_CDK7_CDK7_ST	P49736	MCM2	P50613	CDK7	T59	E52Q	52	Missense	distal	-7	no	23.482	22.317	EPSD;PhosphoSitePlus	GDSC;CCLE	13.598	Down-regulation
CMGC_CDK_CDK7_CDK7_ST	P49736	MCM2	P50613	CDK7	T59	G61E	61	Missense	proximal	2	no	23.482	22.751	EPSD;PhosphoSitePlus	GDSC;CCLE	13.598	Down-regulation
CMGC_CDK_CDK7_CDK7_ST	P49736	MCM2	P50613	CDK7	S108	R115L	115	Missense	distal	7	no	26.698	23.104	EPSD;PhosphoSitePlus	GDSC;CCLE	13.598	Down-regulation
CMGC_CDK_CDK7_CDK7_ST	P49736	MCM2	P50613	CDK7	T598	A603V	603	Missense	distal	5	no	18.631	16.589	EPSD	GDSC;CCLE	13.598	Down-regulation
CMGC_CDK_CDK7_CDK7_ST	P49736	MCM2	P50613	CDK7	S801	K807R	807	Missense	distal	6	no	13.207	14.310	EPSD	GDSC	13.598	Gain
CMGC_CDK_CDK7_CDK7_ST	P49736	MCM2	P50613	CDK7	S813	K807R	807	Missense	distal	-6	no	17.979	18.132	EPSD	GDSC	13.598	Up-regulation
CMGC_CDK_CDK7_CDK7_ST	P24941	CDK2	P50613	CDK7	T160	P155L	155	Missense	distal	-5	no	33.784	32.341	EPSD;PhosphoSitePlus	GDSC;CCLE	13.598	Down-regulation
CMGC_CDK_CDK7_CDK7_ST	Q00534	CDK6	P50613	CDK7	S317	H313Y	313	Missense	distal	-4	no	14.253	14.044	EPSD	GDSC;CCLE	13.598	Down-regulation
CMGC_CDK_CDK7_CDK7_ST	Q00534	CDK6	P50613	CDK7	S317	S317C	317	Missense	central	0	yes	14.253	0.000	EPSD	GDSC	13.598	Loss
CMGC_CDK_CDK7_CDK7_ST	P04637	TP53	P50613	CDK7	S33	Q38*	38	Missense	distal	5	no	20.872	20.520	EPSD;PhosphoSitePlus	GDSC	13.598	Down-regulation
CMGC_CDK_CDK7_CDK7_ST	P04637	TP53	P50613	CDK7	T81	A74S	74	Missense	distal	-7	no	16.811	17.148	EPSD	GDSC;CCLE	13.598	Up-regulation
CMGC_CDK_CDK7_CDK7_ST	P04637	TP53	P50613	CDK7	S127	Y126*	126	Missense	proximal	-1	no	17.259	17.099	EPSD	GDSC	13.598	Down-regulation
CMGC_CDK_CDK7_CDK7_ST	P04637	TP53	P50613	CDK7	S127	K120*	120	Missense	distal	-7	no	17.259	16.303	EPSD	GDSC	13.598	Down-regulation
CMGC_CDK_CDK7_CDK7_ST	P04637	TP53	P50613	CDK7	S315	Q317*	317	Missense	proximal	2	no	14.594	16.876	EPSD	GDSC	13.598	Up-regulation
CMGC_CDK_CDK7_CDK7_ST	P04637	TP53	P50613	CDK7	S315	K319*	319	Missense	distal	4	no	14.594	16.575	EPSD	GDSC	13.598	Up-regulation
CMGC_CDK_CDK7_CDK7_ST	P04637	TP53	P50613	CDK7	T387	G389W	389	Missense	proximal	2	no	12.323	15.138	EPSD	GDSC;CCLE	13.598	Gain
CMGC_CDK_CDK7_CDK7_ST	O00267	SUPT5H	P50613	CDK7	S686	G682D	682	Missense	distal	-4	no	14.289	13.985	EPSD	GDSC;CCLE	13.598	Down-regulation
CMGC_CDK_CDK7_CDK7_ST	O00267	SUPT5H	P50613	CDK7	S763	R757C	757	Missense	distal	-6	no	23.713	23.338	EPSD	GDSC;CCLE	13.598	Down-regulation
CMGC_CDK_CDK7_CDK7_ST	O00267	SUPT5H	P50613	CDK7	T806	G811D	811	Missense	distal	5	no	16.696	17.225	EPSD	GDSC;CCLE	13.598	Up-regulation
CMGC_CDK_CDK7_CDK7_ST	O00267	SUPT5H	P50613	CDK7	T806	D810G	810	Missense	distal	4	no	16.696	13.601	EPSD	GDSC;CCLE	13.598	Down-regulation
CMGC_CDK_CDK7_CDK7_ST	O00267	SUPT5H	P50613	CDK7	S812	G811D	811	Missense	proximal	-1	no	14.513	14.694	EPSD	GDSC;CCLE	13.598	Up-regulation
CMGC_CDK_CDK7_CDK7_ST	O00267	SUPT5H	P50613	CDK7	S812	D810G	810	Missense	proximal	-2	no	14.513	14.873	EPSD	GDSC;CCLE	13.598	Up-regulation
CMGC_CDK_CDK7_CDK7_ST	O00267	SUPT5H	P50613	CDK7	T814	G811D	811	Missense	distal	-3	no	14.065	13.301	EPSD	GDSC;CCLE	13.598	Loss
CMGC_CDK_CDK7_CDK7_ST	O00267	SUPT5H	P50613	CDK7	T814	D810G	810	Missense	distal	-4	no	14.065	14.369	EPSD	GDSC;CCLE	13.598	Up-regulation
CMGC_CDK_CDK7_CDK7_ST	O00267	SUPT5H	P50613	CDK7	T828	T828M	828	Missense	central	0	yes	20.944	0.000	EPSD	GDSC;CCLE	13.598	Loss
CMGC_CDK_CDK7_CDK7_ST	O00267	SUPT5H	P50613	CDK7	S867	Q869L	869	Missense	proximal	2	no	20.493	20.795	EPSD	GDSC;CCLE	13.598	Up-regulation
CMGC_CDK_CDK7_CDK7_ST	P50750	CDK9	P50613	CDK7	T330	F336L	336	Missense	distal	6	no	14.167	15.289	EPSD	GDSC	13.598	Up-regulation
CMGC_CDK_CDK7_CDK7_ST	P24928	POLR2A	P50613	CDK7	S1571	P1569L	1569	Missense	proximal	-2	no	14.917	15.134	EPSD	GDSC;CCLE	13.598	Up-regulation
CMGC_CDK_CDK7_CDK7_ST	P24928	POLR2A	P50613	CDK7	S1571	T1568S	1568	Missense	distal	-3	no	14.917	14.733	EPSD	GDSC;CCLE	13.598	Down-regulation
CMGC_CDK_CDK7_CDK7_ST	P24928	POLR2A	P50613	CDK7	S1616	S1616F	1616	Missense	central	0	yes	21.364	0.000	PhosphoSitePlus;EPSD	GDSC;CCLE	13.598	Loss
CMGC_CDK_CDK7_CDK7_ST	P24928	POLR2A	P50613	CDK7	S1619	S1616F	1616	Missense	distal	-3	no	22.614	21.585	EPSD;PhosphoSitePlus	GDSC;CCLE	13.598	Down-regulation
CMGC_CDK_CDK7_CDK7_ST	P24928	POLR2A	P50613	CDK7	S1621	S1616F	1616	Missense	distal	-5	no	20.619	18.565	EPSD;PhosphoSitePlus	GDSC;CCLE	13.598	Down-regulation
CMGC_CDK_CDK7_CDK7_ST	P24928	POLR2A	P50613	CDK7	S1766	P1764L	1764	Missense	proximal	-2	no	17.842	18.059	EPSD	GDSC;CCLE	13.598	Up-regulation
CMGC_CDK_CDK7_CDK7_ST	P24928	POLR2A	P50613	CDK7	S1962	I1961V	1961	Missense	proximal	-1	no	20.322	20.227	EPSD	GDSC;CCLE	13.598	Down-regulation
CMGC_CDK_CDK7_CDK7_ST	P10276	RARA	P50613	CDK7	S74	P78L	78	Missense	distal	4	no	15.000	13.426	EPSD	GDSC;CCLE	13.598	Loss
CMGC_CDK_CDK7_CDK7_ST	P10276	RARA	P50613	CDK7	S77	P78L	78	Missense	proximal	1	no	23.434	15.964	PhosphoSitePlus	GDSC;CCLE	13.598	Down-regulation
CMGC_CDK_CDK7_CDK7_ST	Q9H0D6	XRN2	P50613	CDK7	T379	K373E	373	Missense	distal	-6	no	15.247	15.541	EPSD	GDSC;CCLE	13.598	Up-regulation
CMGC_CDK_CDK7_CDK7_ST	Q9H0D6	XRN2	P50613	CDK7	T439	R446I	446	Missense	distal	7	no	25.194	25.670	PhosphoSitePlus	GDSC;CCLE	13.598	Up-regulation
CMGC_CDK_CDK7_CDK7_ST	Q9H0D6	XRN2	P50613	CDK7	S448	P449A	449	Missense	proximal	1	no	20.679	1.925	EPSD	GDSC;CCLE	13.598	Loss
CMGC_CDK_CDK7_CDK7_ST	Q9H0D6	XRN2	P50613	CDK7	S448	S451C	451	Missense	distal	3	no	20.679	21.174	EPSD	GDSC;CCLE	13.598	Up-regulation
CMGC_CDK_CDK7_CDK7_ST	Q9H0D6	XRN2	P50613	CDK7	S448	R446I	446	Missense	proximal	-2	no	20.679	20.985	EPSD	GDSC;CCLE	13.598	Up-regulation
CMGC_CDK_CDK7_CDK7_ST	Q01094	E2F1	P50613	CDK7	S313	G309E	309	Missense	distal	-4	no	13.787	12.879	EPSD	GDSC;CCLE	13.598	Loss
CMGC_CDK_CDK7_CDK7_ST	Q01094	E2F1	P50613	CDK7	T344	L351V	351	Missense	distal	7	no	14.121	16.338	EPSD	GDSC;CCLE	13.598	Up-regulation
CMGC_CDK_CDK7_CDK7_ST	Q01094	E2F1	P50613	CDK7	T344	S349Y	349	Missense	distal	5	no	14.121	11.648	EPSD	GDSC;CCLE	13.598	Loss
CMGC_CDK_CDK7_CDK7_ST	Q01094	E2F1	P50613	CDK7	S364	P357Q	357	Missense	distal	-7	no	15.270	14.112	EPSD	GDSC	13.598	Down-regulation
CMGC_CDK_CDK7_CDK7_ST	Q01094	E2F1	P50613	CDK7	S403	A408T	408	Missense	distal	5	no	24.807	23.229	EPSD;PhosphoSitePlus	GDSC;CCLE	13.598	Down-regulation
CMGC_CDK_CDK7_CDK7_ST	Q9BYE7	PCGF6	P50613	CDK7	S115	D117N	117	Missense	proximal	2	no	14.289	13.387	EPSD	GDSC;CCLE	13.598	Loss
CMGC_CDK_CDK7_CDK7_ST	Q9BYE7	PCGF6	P50613	CDK7	S115	R121H	121	Missense	distal	6	no	14.289	13.616	EPSD	GDSC	13.598	Down-regulation
CMGC_CDK_CDK7_CDK7_ST	Q9BYE7	PCGF6	P50613	CDK7	S345	G341V	341	Missense	distal	-4	no	14.779	14.314	EPSD	GDSC;CCLE	13.598	Down-regulation
CMGC_CDK_CDK7_CDK7_ST	Q9BYE7	PCGF6	P50613	CDK7	S345	H339R	339	Missense	distal	-6	no	14.779	15.491	EPSD	GDSC;CCLE	13.598	Up-regulation
CMGC_CDK_CDK7_CDK7_ST	P13631	RARG	P50613	CDK7	S43	G50D	50	Missense	distal	7	no	21.011	18.530	EPSD	GDSC;CCLE	13.598	Down-regulation
CMGC_CDK_CDK7_CDK7_ST	Q9NYV4	CDK12	P50613	CDK7	T82	T82A	82	Missense	central	0	yes	13.919	0.000	EPSD	GDSC;CCLE	13.598	Loss
CMGC_CDK_CDK7_CDK7_ST	Q9NYV4	CDK12	P50613	CDK7	S681	P683L	683	Missense	proximal	2	no	13.627	13.212	EPSD	GDSC;CCLE	13.598	Loss
CMGC_CDK_CDK7_CDK7_ST	Q9NYV4	CDK12	P50613	CDK7	S685	P683L	683	Missense	proximal	-2	no	15.799	16.015	EPSD	GDSC;CCLE	13.598	Up-regulation
CMGC_CDK_CDK7_CDK7_ST	Q9NYV4	CDK12	P50613	CDK7	S949	R950*	950	Missense	proximal	1	no	14.633	6.566	EPSD	GDSC	13.598	Loss
CMGC_CDK_CDK7_CDK7_ST	Q9NYV4	CDK12	P50613	CDK7	S949	I948V	948	Missense	proximal	-1	no	14.633	14.538	EPSD	GDSC;CCLE	13.598	Down-regulation
CMGC_CDK_CDK7_CDK7_ST	Q9NYV4	CDK12	P50613	CDK7	S954	R950*	950	Missense	distal	-4	no	18.266	19.553	EPSD	GDSC	13.598	Up-regulation
CMGC_CDK_CDK7_CDK7_ST	Q9NYV4	CDK12	P50613	CDK7	S954	I948V	948	Missense	distal	-6	no	18.266	18.271	EPSD	GDSC;CCLE	13.598	Up-regulation
CMGC_CDK_CDK7_CDK7_ST	Q9NYV4	CDK12	P50613	CDK7	S1063	E1069*	1069	Missense	distal	6	no	14.709	13.901	EPSD	GDSC	13.598	Down-regulation
CMGC_CDK_CDK7_CDK7_ST	Q9NYV4	CDK12	P50613	CDK7	S1083	Q1088*	1088	Missense	distal	5	no	16.701	16.349	EPSD	GDSC	13.598	Down-regulation
CMGC_CDK_CDK7_CDK7_ST	P10275	AR	P50613	CDK7	S516	E523D	523	Missense	distal	7	no	26.004	23.313	PhosphoSitePlus	GDSC	13.598	Down-regulation
AGC_NDR_NDR_STK38_ST	P46937	YAP1	Q15208	STK38	S94	P98L	98	Missense	distal	4	no	0.214	0.215	EPSD	GDSC;CCLE	0.133	Up-regulation
AGC_NDR_NDR_STK38_ST	P46937	YAP1	Q15208	STK38	S164	R161*	161	Missense	distal	-3	no	2.147	1.658	EPSD;PhosphoSitePlus	GDSC	0.133	Down-regulation
AGC_NDR_NDR_STK38_ST	Q02241	KIF23	Q15208	STK38	S684	V683I	683	Missense	proximal	-1	no	0.350	0.349	EPSD	GDSC;CCLE	0.133	Down-regulation
AGC_NDR_NDR_STK38_ST	Q02241	KIF23	Q15208	STK38	S686	V683I	683	Missense	distal	-3	no	0.137	0.240	EPSD	GDSC;CCLE	0.133	Up-regulation
AGC_NDR_NDR_STK38_ST	Q02241	KIF23	Q15208	STK38	T843	A841V	841	Missense	proximal	-2	no	0.224	0.219	EPSD	GDSC	0.133	Down-regulation
CAMK_CAMKL_AMPK_PRKAA1_ST	Q9Y478	PRKAB1	Q13131	PRKAA1	S24	G27V	27	Missense	distal	3	no	60.885	60.579	EPSD;PhosphoSitePlus	GDSC	56.683	Down-regulation
CAMK_CAMKL_AMPK_PRKAA1_ST	Q9Y478	PRKAB1	Q13131	PRKAA1	S25	G27V	27	Missense	proximal	2	no	60.119	61.574	EPSD	GDSC	56.683	Up-regulation
CAMK_CAMKL_AMPK_PRKAA1_ST	Q9Y478	PRKAB1	Q13131	PRKAA1	S108	N110Y	110	Missense	proximal	2	no	64.453	64.230	PhosphoSitePlus;EPSD	GDSC;CCLE	56.683	Down-regulation
CAMK_CAMKL_AMPK_PRKAA1_ST	P10636	MAPT	Q13131	PRKAA1	S171	D177V	177	Missense	distal	6	no	59.279	59.468	EPSD	GDSC	56.683	Up-regulation
CAMK_CAMKL_AMPK_PRKAA1_ST	P10636	MAPT	Q13131	PRKAA1	S214	V218G	218	Missense	distal	4	no	71.752	68.566	EPSD;PhosphoSitePlus	GDSC	56.683	Down-regulation
CAMK_CAMKL_AMPK_PRKAA1_ST	P05091	ALDH2	Q13131	PRKAA1	T441	G443R	443	Missense	proximal	2	no	66.092	66.696	EPSD	GDSC;CCLE	56.683	Up-regulation
CAMK_CAMKL_AMPK_PRKAA1_ST	Q7Z3C6	ATG9A	Q13131	PRKAA1	S654	Q659H	659	Missense	distal	5	no	62.685	62.447	EPSD	GDSC	56.683	Down-regulation
CAMK_CAMKL_AMPK_PRKAA1_ST	Q7Z3C6	ATG9A	Q13131	PRKAA1	S738	R732H	732	Missense	distal	-6	no	63.700	62.166	EPSD	GDSC	56.683	Down-regulation
CAMK_CAMKL_AMPK_PRKAA1_ST	Q7Z3C6	ATG9A	Q13131	PRKAA1	S761	A760V	760	Missense	proximal	-1	no	63.081	62.990	PhosphoSitePlus	GDSC;CCLE	56.683	Down-regulation
CAMK_CAMKL_AMPK_PRKAA1_ST	Q7Z628	NET1	Q13131	PRKAA1	T119	G117D	117	Missense	proximal	-2	no	55.992	57.584	EPSD	GDSC;CCLE	56.683	Gain
CAMK_CAMKL_AMPK_PRKAA1_ST	Q7Z628	NET1	Q13131	PRKAA1	S140	K137R	137	Missense	distal	-3	no	52.044	56.685	EPSD	GDSC;CCLE	56.683	Gain
CAMK_CAMKL_AMPK_PRKAA1_ST	P07954	FH	Q13131	PRKAA1	T56	E53K	53	Missense	distal	-3	no	64.956	68.797	EPSD	GDSC;CCLE	56.683	Up-regulation
CAMK_CAMKL_AMPK_PRKAA1_ST	Q8IY63	AMOTL1	Q13131	PRKAA1	S724	N718K	718	Missense	distal	-6	no	58.458	57.326	EPSD	GDSC;CCLE	56.683	Down-regulation
CAMK_CAMKL_AMPK_PRKAA1_ST	Q13131	PRKAA1	Q13131	PRKAA1	T37	G34R	34	Missense	distal	-3	no	56.820	65.855	EPSD	GDSC;CCLE	56.683	Up-regulation
CAMK_CAMKL_AMPK_PRKAA1_ST	Q15036	SNX17	Q13131	PRKAA1	S335	G342A	342	Missense	distal	7	no	58.513	58.692	EPSD	GDSC	56.683	Up-regulation
CAMK_CAMKL_AMPK_PRKAA1_ST	Q15036	SNX17	Q13131	PRKAA1	S388	K394N	394	Missense	distal	6	no	58.391	58.328	EPSD	GDSC	56.683	Down-regulation
CAMK_CAMKL_AMPK_PRKAA1_ST	Q15036	SNX17	Q13131	PRKAA1	T425	R426L	426	Missense	proximal	1	no	57.049	57.111	EPSD	GDSC;CCLE	56.683	Up-regulation
CAMK_CAMKL_AMPK_PRKAA1_ST	Q15036	SNX17	Q13131	PRKAA1	S428	R426L	426	Missense	proximal	-2	no	60.645	59.458	EPSD	GDSC;CCLE	56.683	Down-regulation
CAMK_CAMKL_AMPK_PRKAA1_ST	Q9UQL6	HDAC5	Q13131	PRKAA1	S1108	E1114Q	1114	Missense	distal	6	no	60.786	60.935	EPSD	GDSC	56.683	Up-regulation
CAMK_CAMKL_AMPK_PRKAA1_ST	P04406	GAPDH	Q13131	PRKAA1	S122	S125C	125	Missense	distal	3	no	57.178	55.347	PhosphoSitePlus	GDSC;CCLE	56.683	Loss
CAMK_CAMKL_AMPK_PRKAA1_ST	P04406	GAPDH	Q13131	PRKAA1	T237	P236S	236	Missense	proximal	-1	no	66.762	66.807	EPSD	GDSC;CCLE	56.683	Up-regulation
CAMK_CAMKL_AMPK_PRKAA1_ST	P04406	GAPDH	Q13131	PRKAA1	S241	P236S	236	Missense	distal	-5	no	57.768	58.326	EPSD	GDSC;CCLE	56.683	Up-regulation
CAMK_CAMKL_AMPK_PRKAA1_ST	P04406	GAPDH	Q13131	PRKAA1	T294	A297G	297	Missense	distal	3	no	51.839	57.021	EPSD	GDSC;CCLE	56.683	Gain
CAMK_CAMKL_AMPK_PRKAA1_ST	P29474	NOS3	Q13131	PRKAA1	S633	R627Q	627	Missense	distal	-6	no	77.542	77.900	EPSD;PhosphoSitePlus	GDSC;CCLE	56.683	Up-regulation
CAMK_CAMKL_AMPK_PRKAA1_ST	P29474	NOS3	Q13131	PRKAA1	S633	R628Q	628	Missense	distal	-5	no	77.542	71.860	EPSD;PhosphoSitePlus	GDSC	56.683	Down-regulation
CAMK_CAMKL_AMPK_PRKAA1_ST	P29474	NOS3	Q13131	PRKAA1	S634	R627Q	627	Missense	distal	-7	no	61.470	61.647	EPSD	GDSC;CCLE	56.683	Up-regulation
CAMK_CAMKL_AMPK_PRKAA1_ST	P29474	NOS3	Q13131	PRKAA1	S634	R628Q	628	Missense	distal	-6	no	61.470	61.828	EPSD	GDSC	56.683	Up-regulation
CAMK_CAMKL_AMPK_PRKAA1_ST	P29474	NOS3	Q13131	PRKAA1	S634	A641S	641	Missense	distal	7	no	61.470	61.342	EPSD	GDSC;CCLE	56.683	Down-regulation
CAMK_CAMKL_AMPK_PRKAA1_ST	P29474	NOS3	Q13131	PRKAA1	S1177	R1174C	1174	Missense	distal	-3	no	71.268	57.120	PhosphoSitePlus;EPSD	GDSC;CCLE	56.683	Down-regulation
CAMK_CAMKL_AMPK_PRKAA1_ST	P29474	NOS3	Q13131	PRKAA1	S1177	R1172C	1172	Missense	distal	-5	no	71.268	69.914	PhosphoSitePlus;EPSD	GDSC;CCLE	56.683	Down-regulation
CAMK_CAMKL_AMPK_PRKAA1_ST	P29474	NOS3	Q13131	PRKAA1	S1177	T1175S	1175	Missense	proximal	-2	no	71.268	73.951	PhosphoSitePlus;EPSD	GDSC;CCLE	56.683	Up-regulation
CAMK_CAMKL_AMPK_PRKAA1_ST	P29474	NOS3	Q13131	PRKAA1	S1177	T1170K	1170	Missense	distal	-7	no	71.268	73.728	PhosphoSitePlus;EPSD	GDSC	56.683	Up-regulation
CAMK_CAMKL_AMPK_PRKAA1_ST	P29474	NOS3	Q13131	PRKAA1	S1177	I1173T	1173	Missense	distal	-4	no	71.268	72.811	PhosphoSitePlus;EPSD	GDSC;CCLE	56.683	Up-regulation
CAMK_CAMKL_AMPK_PRKAA1_ST	P29474	NOS3	Q13131	PRKAA1	S1179	R1174C	1174	Missense	distal	-5	no	63.880	62.526	EPSD	GDSC;CCLE	56.683	Down-regulation
CAMK_CAMKL_AMPK_PRKAA1_ST	P29474	NOS3	Q13131	PRKAA1	S1179	R1172C	1172	Missense	distal	-7	no	63.880	62.488	EPSD	GDSC;CCLE	56.683	Down-regulation
CAMK_CAMKL_AMPK_PRKAA1_ST	P29474	NOS3	Q13131	PRKAA1	S1179	T1175S	1175	Missense	distal	-4	no	63.880	65.136	EPSD	GDSC;CCLE	56.683	Up-regulation
CAMK_CAMKL_AMPK_PRKAA1_ST	P29474	NOS3	Q13131	PRKAA1	S1179	I1173T	1173	Missense	distal	-6	no	63.880	67.020	EPSD	GDSC;CCLE	56.683	Up-regulation
CAMK_CAMKL_AMPK_PRKAA1_ST	P50552	VASP	Q13131	PRKAA1	S157	R155Q	155	Missense	proximal	-2	no	63.922	64.385	EPSD	GDSC	56.683	Up-regulation
CAMK_CAMKL_AMPK_PRKAA1_ST	P50552	VASP	Q13131	PRKAA1	S157	N158H	158	Missense	proximal	1	no	63.922	66.787	EPSD	GDSC	56.683	Up-regulation
CAMK_CAMKL_AMPK_PRKAA1_ST	P50552	VASP	Q13131	PRKAA1	S338	T335M	335	Missense	distal	-3	no	58.626	59.854	EPSD	GDSC	56.683	Up-regulation
CAMK_CAMKL_AMPK_PRKAA1_ST	P50552	VASP	Q13131	PRKAA1	S338	Q345*	345	Missense	distal	7	no	58.626	59.751	EPSD	GDSC	56.683	Up-regulation
CAMK_CAMKL_AMPK_PRKAA1_ST	Q9UQK1	PPP1R3C	Q13131	PRKAA1	T170	R167*	167	Missense	distal	-3	no	70.453	29.595	EPSD	GDSC	56.683	Loss
CAMK_CAMKL_AMPK_PRKAA1_ST	P23458	JAK1	Q13131	PRKAA1	S228	E223*	223	Missense	distal	-5	no	57.763	55.507	EPSD	GDSC	56.683	Loss
CAMK_CAMKL_AMPK_PRKAA1_ST	P23458	JAK1	Q13131	PRKAA1	S515	F516S	516	Missense	proximal	1	no	65.849	61.309	EPSD;PhosphoSitePlus	GDSC;CCLE	56.683	Down-regulation
CAMK_CAMKL_AMPK_PRKAA1_ST	P23458	JAK1	Q13131	PRKAA1	S518	F516S	516	Missense	proximal	-2	no	58.438	60.636	PhosphoSitePlus;EPSD	GDSC;CCLE	56.683	Up-regulation
CAMK_CAMKL_AMPK_PRKAA1_ST	P46937	YAP1	Q13131	PRKAA1	S94	P98L	98	Missense	distal	4	no	60.995	67.735	EPSD;PhosphoSitePlus	GDSC;CCLE	56.683	Up-regulation
CAMK_CAMKL_AMPK_PRKAA1_ST	P46937	YAP1	Q13131	PRKAA1	S229	A228V	228	Missense	proximal	-1	no	57.527	57.436	EPSD	GDSC;CCLE	56.683	Down-regulation
CAMK_CAMKL_AMPK_PRKAA1_ST	P46937	YAP1	Q13131	PRKAA1	T378	D383A	383	Missense	distal	5	no	66.144	66.083	EPSD	GDSC;CCLE	56.683	Down-regulation
CAMK_CAMKL_AMPK_PRKAA1_ST	P46937	YAP1	Q13131	PRKAA1	S382	D383A	383	Missense	proximal	1	no	61.508	60.752	EPSD	GDSC;CCLE	56.683	Down-regulation
CAMK_CAMKL_AMPK_PRKAA1_ST	P46937	YAP1	Q13131	PRKAA1	T390	D383A	383	Missense	distal	-7	no	57.287	55.469	EPSD	GDSC;CCLE	56.683	Loss
CAMK_CAMKL_AMPK_PRKAA1_ST	P46937	YAP1	Q13131	PRKAA1	S499	S499G	499	Missense	central	0	yes	57.882	0.000	EPSD	GDSC;CCLE	56.683	Loss
CAMK_CAMKL_AMPK_PRKAA1_ST	P63244	RACK1	Q13131	PRKAA1	T39	S35F	35	Missense	distal	-4	no	60.886	59.039	EPSD	GDSC	56.683	Down-regulation
CAMK_CAMKL_AMPK_PRKAA1_ST	Q9H0B6	KLC2	Q13131	PRKAA1	S328	Q326K	326	Missense	proximal	-2	no	56.562	57.478	EPSD	GDSC;CCLE	56.683	Gain
CAMK_CAMKL_AMPK_PRKAA1_ST	Q9H0B6	KLC2	Q13131	PRKAA1	S499	R501K	501	Missense	proximal	2	no	59.269	59.385	EPSD	GDSC;CCLE	56.683	Up-regulation
CAMK_CAMKL_AMPK_PRKAA1_ST	Q9H0B6	KLC2	Q13131	PRKAA1	S519	G514R	514	Missense	distal	-5	no	55.434	58.443	EPSD	GDSC	56.683	Gain
CAMK_CAMKL_AMPK_PRKAA1_ST	Q9H0B6	KLC2	Q13131	PRKAA1	S545	A552V	552	Missense	distal	7	no	79.895	77.477	PhosphoSitePlus;EPSD	GDSC	56.683	Down-regulation
CAMK_CAMKL_AMPK_PRKAA1_ST	Q9H0B6	KLC2	Q13131	PRKAA1	S557	A552V	552	Missense	distal	-5	no	62.084	60.891	EPSD	GDSC	56.683	Down-regulation
CAMK_CAMKL_AMPK_PRKAA1_ST	P09874	PARP1	Q13131	PRKAA1	S257	E251K	251	Missense	distal	-6	no	65.400	65.770	EPSD	GDSC;CCLE	56.683	Up-regulation
CAMK_CAMKL_AMPK_PRKAA1_ST	P09874	PARP1	Q13131	PRKAA1	S299	E297*	297	Missense	proximal	-2	no	58.219	51.547	EPSD	GDSC	56.683	Loss
CAMK_CAMKL_AMPK_PRKAA1_ST	P09874	PARP1	Q13131	PRKAA1	T361	P358L	358	Missense	distal	-3	no	60.148	59.041	EPSD	GDSC	56.683	Down-regulation
CAMK_CAMKL_AMPK_PRKAA1_ST	P09874	PARP1	Q13131	PRKAA1	T361	R355G	355	Missense	distal	-6	no	60.148	59.183	EPSD	GDSC	56.683	Down-regulation
CAMK_CAMKL_AMPK_PRKAA1_ST	P09874	PARP1	Q13131	PRKAA1	T361	D354A	354	Missense	distal	-7	no	60.148	58.330	EPSD	GDSC;CCLE	56.683	Down-regulation
CAMK_CAMKL_AMPK_PRKAA1_ST	P09874	PARP1	Q13131	PRKAA1	S455	N450S	450	Missense	distal	-5	no	44.912	59.840	EPSD	GDSC	56.683	Gain
CAMK_CAMKL_AMPK_PRKAA1_ST	P09874	PARP1	Q13131	PRKAA1	S507	S507N	507	Missense	central	0	yes	61.478	0.000	EPSD	GDSC;CCLE	56.683	Loss
CAMK_CAMKL_AMPK_PRKAA1_ST	P09874	PARP1	Q13131	PRKAA1	S606	M604I	604	Missense	proximal	-2	no	58.313	58.849	EPSD	GDSC;CCLE	56.683	Up-regulation
CAMK_CAMKL_AMPK_PRKAA1_ST	P09874	PARP1	Q13131	PRKAA1	S681	A685T	685	Missense	distal	4	no	69.737	67.169	EPSD	GDSC;CCLE	56.683	Down-regulation
CAMK_CAMKL_AMPK_PRKAA1_ST	P52292	KPNA2	Q13131	PRKAA1	S55	S62Y	62	Missense	distal	7	no	58.087	58.336	EPSD	GDSC;CCLE	56.683	Up-regulation
CAMK_CAMKL_AMPK_PRKAA1_ST	P52292	KPNA2	Q13131	PRKAA1	S105	Q98E	98	Missense	distal	-7	no	57.175	57.209	PhosphoSitePlus	GDSC;CCLE	56.683	Up-regulation
CAMK_CAMKL_AMPK_PRKAA1_ST	P52292	KPNA2	Q13131	PRKAA1	T232	T230A	230	Missense	proximal	-2	no	58.401	59.059	EPSD	GDSC;CCLE	56.683	Up-regulation
CAMK_CAMKL_AMPK_PRKAA1_ST	P52292	KPNA2	Q13131	PRKAA1	T232	N228D	228	Missense	distal	-4	no	58.401	64.171	EPSD	GDSC;CCLE	56.683	Up-regulation
CAMK_CAMKL_AMPK_PRKAA1_ST	O00418	EEF2K	Q13131	PRKAA1	S72	Y69H	69	Missense	distal	-3	no	49.790	58.164	EPSD	GDSC;CCLE	56.683	Gain
CAMK_CAMKL_AMPK_PRKAA1_ST	O60825	PFKFB2	Q13131	PRKAA1	T52	R49Q	49	Missense	distal	-3	no	59.424	51.480	EPSD	GDSC;CCLE	56.683	Loss
CAMK_CAMKL_AMPK_PRKAA1_ST	O60825	PFKFB2	Q13131	PRKAA1	T52	V54M	54	Missense	proximal	2	no	59.424	58.572	EPSD	GDSC	56.683	Down-regulation
CAMK_CAMKL_AMPK_PRKAA1_ST	O60825	PFKFB2	Q13131	PRKAA1	T52	R49L	49	Missense	distal	-3	no	59.424	49.457	EPSD	GDSC;CCLE	56.683	Loss
CAMK_CAMKL_AMPK_PRKAA1_ST	O60825	PFKFB2	Q13131	PRKAA1	T458	N451H	451	Missense	distal	-7	no	57.719	54.790	EPSD	GDSC	56.683	Loss
CAMK_CAMKL_AMPK_PRKAA1_ST	O60825	PFKFB2	Q13131	PRKAA1	T458	N456S	456	Missense	proximal	-2	no	57.719	58.379	EPSD	GDSC;CCLE	56.683	Up-regulation
CAMK_CAMKL_AMPK_PRKAA1_ST	O60825	PFKFB2	Q13131	PRKAA1	S466	S472G	472	Missense	distal	6	no	70.731	70.503	PhosphoSitePlus	GDSC;CCLE	56.683	Down-regulation
CAMK_CAMKL_AMPK_PRKAA1_ST	O60825	PFKFB2	Q13131	PRKAA1	S483	P488L	488	Missense	distal	5	no	60.167	60.160	EPSD	GDSC;CCLE	56.683	Down-regulation
CAMK_CAMKL_AMPK_PRKAA1_ST	O60825	PFKFB2	Q13131	PRKAA1	S493	P494A	494	Missense	proximal	1	no	59.079	58.117	EPSD	GDSC;CCLE	56.683	Down-regulation
CAMK_CAMKL_AMPK_PRKAA1_ST	O60825	PFKFB2	Q13131	PRKAA1	S493	Q498L	498	Missense	distal	5	no	59.079	59.031	EPSD	GDSC;CCLE	56.683	Down-regulation
CAMK_CAMKL_AMPK_PRKAA1_ST	O60825	PFKFB2	Q13131	PRKAA1	S493	R496C	496	Missense	distal	3	no	59.079	57.899	EPSD	GDSC	56.683	Down-regulation
CAMK_CAMKL_AMPK_PRKAA1_ST	O60825	PFKFB2	Q13131	PRKAA1	S493	M500L	500	Missense	distal	7	no	59.079	61.083	EPSD	GDSC;CCLE	56.683	Up-regulation
CAMK_CAMKL_AMPK_PRKAA1_ST	O60825	PFKFB2	Q13131	PRKAA1	S493	P488L	488	Missense	distal	-5	no	59.079	63.820	EPSD	GDSC;CCLE	56.683	Up-regulation
CAMK_CAMKL_AMPK_PRKAA1_ST	P13569	CFTR	Q13131	PRKAA1	S686	T690A	690	Missense	distal	4	no	67.697	70.265	EPSD	GDSC;CCLE	56.683	Up-regulation
CAMK_CAMKL_AMPK_PRKAA1_ST	P13569	CFTR	Q13131	PRKAA1	S686	K688N	688	Missense	proximal	2	no	67.697	67.243	EPSD	GDSC;CCLE	56.683	Down-regulation
CAMK_CAMKL_AMPK_PRKAA1_ST	P13569	CFTR	Q13131	PRKAA1	S686	E681V	681	Missense	distal	-5	no	67.697	64.452	EPSD	GDSC	56.683	Down-regulation
CAMK_CAMKL_AMPK_PRKAA1_ST	P13569	CFTR	Q13131	PRKAA1	S712	I705T	705	Missense	distal	-7	no	58.167	58.665	EPSD	GDSC;CCLE	56.683	Up-regulation
CAMK_CAMKL_AMPK_PRKAA1_ST	P13569	CFTR	Q13131	PRKAA1	S813	Q814L	814	Missense	proximal	1	no	62.646	63.587	EPSD;PhosphoSitePlus	GDSC;CCLE	56.683	Up-regulation
CAMK_CAMKL_AMPK_PRKAA1_ST	P13569	CFTR	Q13131	PRKAA1	S1248	G1244E	1244	Missense	distal	-4	no	65.680	69.233	EPSD	GDSC;CCLE	56.683	Up-regulation
CAMK_CAMKL_AMPK_PRKAA1_ST	P13569	CFTR	Q13131	PRKAA1	S1455	R1453W	1453	Missense	proximal	-2	no	60.208	57.869	EPSD	GDSC	56.683	Down-regulation
CAMK_CAMKL_AMPK_PRKAA1_ST	P22460	KCNA5	Q13131	PRKAA1	S127	V122I	122	Missense	distal	-5	no	57.242	62.685	EPSD	GDSC	56.683	Up-regulation
CAMK_CAMKL_AMPK_PRKAA1_ST	P22460	KCNA5	Q13131	PRKAA1	S127	N125D	125	Missense	proximal	-2	no	57.242	56.191	EPSD	GDSC;CCLE	56.683	Loss
CAMK_CAMKL_AMPK_PRKAA1_ST	P22460	KCNA5	Q13131	PRKAA1	S127	S127F	127	Missense	central	0	yes	57.242	0.000	EPSD	GDSC;CCLE	56.683	Loss
CAMK_CAMKL_AMPK_PRKAA1_ST	P22460	KCNA5	Q13131	PRKAA1	S557	S557R	557	Missense	central	0	yes	59.359	0.000	EPSD	GDSC;CCLE	56.683	Loss
CAMK_CAMKL_AMPK_PRKAA1_ST	O43524	FOXO3	Q13131	PRKAA1	S253	R249W	249	Missense	distal	-4	no	63.963	55.300	EPSD	GDSC;CCLE	56.683	Loss
CAMK_CAMKL_AMPK_PRKAA1_ST	O43524	FOXO3	Q13131	PRKAA1	T313	V320I	320	Missense	distal	7	no	69.035	70.233	EPSD	GDSC;CCLE	56.683	Up-regulation
CAMK_CAMKL_AMPK_PRKAA1_ST	O43524	FOXO3	Q13131	PRKAA1	S413	R410W	410	Missense	distal	-3	no	72.932	-20.068	EPSD;PhosphoSitePlus	GDSC;CCLE	56.683	Loss
CAMK_CAMKL_AMPK_PRKAA1_ST	O43524	FOXO3	Q13131	PRKAA1	S413	M408V	408	Missense	distal	-5	no	72.932	68.236	EPSD;PhosphoSitePlus	GDSC;CCLE	56.683	Down-regulation
CAMK_CAMKL_AMPK_PRKAA1_ST	O43524	FOXO3	Q13131	PRKAA1	S555	E561D	561	Missense	distal	6	no	67.996	67.523	EPSD;PhosphoSitePlus	GDSC	56.683	Down-regulation
CAMK_CAMKL_AMPK_PRKAA1_ST	O43524	FOXO3	Q13131	PRKAA1	S564	E561D	561	Missense	distal	-3	no	61.248	59.877	EPSD	GDSC	56.683	Down-regulation
CAMK_CAMKL_AMPK_PRKAA1_ST	P46527	CDKN1B	Q13131	PRKAA1	S83	E86K	86	Missense	distal	3	no	58.576	60.301	EPSD	GDSC;CCLE	56.683	Up-regulation
CAMK_CAMKL_AMPK_PRKAA1_ST	P46527	CDKN1B	Q13131	PRKAA1	S140	E146Q	146	Missense	distal	6	no	63.949	64.098	EPSD	GDSC;CCLE	56.683	Up-regulation
CAMK_CAMKL_AMPK_PRKAA1_ST	P46527	CDKN1B	Q13131	PRKAA1	S140	P137L	137	Missense	distal	-3	no	63.949	62.842	EPSD	GDSC;CCLE	56.683	Down-regulation
CAMK_CAMKL_AMPK_PRKAA1_ST	P46527	CDKN1B	Q13131	PRKAA1	T157	P155L	155	Missense	proximal	-2	no	57.685	54.710	EPSD	GDSC;CCLE	56.683	Loss
CAMK_CAMKL_AMPK_PRKAA1_ST	P46527	CDKN1B	Q13131	PRKAA1	S175	G177S	177	Missense	proximal	2	no	59.348	59.857	EPSD	GDSC;CCLE	56.683	Up-regulation
CAMK_CAMKL_AMPK_PRKAA1_ST	P08151	GLI1	Q13131	PRKAA1	S84	P87S	87	Missense	distal	3	no	60.430	62.668	EPSD	GDSC;CCLE	56.683	Up-regulation
CAMK_CAMKL_AMPK_PRKAA1_ST	P08151	GLI1	Q13131	PRKAA1	S89	P87S	87	Missense	proximal	-2	no	60.189	59.640	EPSD	GDSC;CCLE	56.683	Down-regulation
CAMK_CAMKL_AMPK_PRKAA1_ST	P08151	GLI1	Q13131	PRKAA1	S538	R531H	531	Missense	distal	-7	no	58.830	55.807	EPSD	GDSC;CCLE	56.683	Loss
CAMK_CAMKL_AMPK_PRKAA1_ST	P08151	GLI1	Q13131	PRKAA1	S538	R542C	542	Missense	distal	4	no	58.830	37.977	EPSD	GDSC;CCLE	56.683	Loss
CAMK_CAMKL_AMPK_PRKAA1_ST	P08151	GLI1	Q13131	PRKAA1	S538	S545G	545	Missense	distal	7	no	58.830	58.780	EPSD	GDSC;CCLE	56.683	Down-regulation
CAMK_CAMKL_AMPK_PRKAA1_ST	P08151	GLI1	Q13131	PRKAA1	S545	R542C	542	Missense	distal	-3	no	73.952	59.804	EPSD	GDSC;CCLE	56.683	Down-regulation
CAMK_CAMKL_AMPK_PRKAA1_ST	P08151	GLI1	Q13131	PRKAA1	S545	S545G	545	Missense	central	0	yes	73.952	0.000	EPSD	GDSC;CCLE	56.683	Loss
CAMK_CAMKL_AMPK_PRKAA1_ST	P08151	GLI1	Q13131	PRKAA1	S939	V936I	936	Missense	distal	-3	no	56.934	51.951	EPSD	GDSC;CCLE	56.683	Loss
CAMK_CAMKL_AMPK_PRKAA1_ST	Q9BZL4	PPP1R12C	Q13131	PRKAA1	S544	K547N	547	Missense	distal	3	no	57.037	58.275	EPSD	GDSC;CCLE	56.683	Up-regulation
CAMK_CAMKL_AMPK_PRKAA1_ST	Q9BZL4	PPP1R12C	Q13131	PRKAA1	S559	R557Q	557	Missense	proximal	-2	no	63.273	63.735	EPSD	GDSC;CCLE	56.683	Up-regulation
CAMK_CAMKL_AMPK_PRKAA1_ST	P04637	TP53	Q13131	PRKAA1	S99	Q100*	100	Missense	proximal	1	no	54.806	57.386	EPSD	GDSC	56.683	Gain
CAMK_CAMKL_AMPK_PRKAA1_ST	P04637	TP53	Q13131	PRKAA1	S106	K101*	101	Missense	distal	-5	no	57.242	57.634	EPSD	GDSC	56.683	Up-regulation
CAMK_CAMKL_AMPK_PRKAA1_ST	P04637	TP53	Q13131	PRKAA1	S106	Q100*	100	Missense	distal	-6	no	57.242	52.883	EPSD	GDSC	56.683	Loss
CAMK_CAMKL_AMPK_PRKAA1_ST	P04637	TP53	Q13131	PRKAA1	S106	Y107*	107	Missense	proximal	1	no	57.242	55.640	EPSD	GDSC	56.683	Loss
CAMK_CAMKL_AMPK_PRKAA1_ST	P04637	TP53	Q13131	PRKAA1	S269	E271*	271	Missense	proximal	2	no	57.267	55.010	EPSD	GDSC	56.683	Loss
CAMK_CAMKL_AMPK_PRKAA1_ST	P04637	TP53	Q13131	PRKAA1	S313	Q317*	317	Missense	distal	4	no	54.373	57.588	EPSD	GDSC	56.683	Gain
CAMK_CAMKL_AMPK_PRKAA1_ST	P04637	TP53	Q13131	PRKAA1	S367	G360V	360	Missense	distal	-7	no	60.689	58.891	EPSD	GDSC;CCLE	56.683	Down-regulation
CAMK_CAMKL_AMPK_PRKAA1_ST	P00533	EGFR	Q13131	PRKAA1	S752	A750E	750	Missense	proximal	-2	no	59.697	60.585	EPSD	GDSC	56.683	Up-regulation
CAMK_CAMKL_AMPK_PRKAA1_ST	P00533	EGFR	Q13131	PRKAA1	T1150	W1157C	1157	Missense	distal	7	no	66.138	65.946	EPSD	GDSC;CCLE	56.683	Down-regulation
CAMK_CAMKL_AMPK_PRKAA1_ST	Q92538	GBF1	Q13131	PRKAA1	S1298	G1295R	1295	Missense	distal	-3	no	59.577	68.613	EPSD	GDSC	56.683	Up-regulation
CAMK_CAMKL_AMPK_PRKAA1_ST	Q92538	GBF1	Q13131	PRKAA1	S1444	G1437C	1437	Missense	distal	-7	no	59.605	56.797	EPSD	GDSC;CCLE	56.683	Down-regulation
CAMK_CAMKL_AMPK_PRKAA1_ST	Q92538	GBF1	Q13131	PRKAA1	S1444	K1451R	1451	Missense	distal	7	no	59.605	60.492	EPSD	GDSC;CCLE	56.683	Up-regulation
CAMK_CAMKL_AMPK_PRKAA1_ST	Q92538	GBF1	Q13131	PRKAA1	S1453	K1451R	1451	Missense	proximal	-2	no	57.301	55.923	EPSD	GDSC;CCLE	56.683	Loss
CAMK_CAMKL_AMPK_PRKAA1_ST	Q92538	GBF1	Q13131	PRKAA1	S1457	K1451R	1451	Missense	distal	-6	no	64.775	66.256	EPSD	GDSC;CCLE	56.683	Up-regulation
CAMK_CAMKL_AMPK_PRKAA1_ST	Q92538	GBF1	Q13131	PRKAA1	S1465	R1471W	1471	Missense	distal	6	no	59.588	59.098	EPSD	GDSC;CCLE	56.683	Down-regulation
CAMK_CAMKL_AMPK_PRKAA1_ST	Q92538	GBF1	Q13131	PRKAA1	S1773	E1769K	1769	Missense	distal	-4	no	57.439	54.314	EPSD	GDSC;CCLE	56.683	Loss
CAMK_CAMKL_AMPK_PRKAA1_ST	P60891	PRPS1	Q13131	PRKAA1	S180	D183N	183	Missense	distal	3	no	66.721	67.975	PhosphoSitePlus	GDSC;CCLE	56.683	Up-regulation
CAMK_CAMKL_AMPK_PRKAA1_ST	P60891	PRPS1	Q13131	PRKAA1	S308	T303A	303	Missense	distal	-5	no	55.922	57.914	EPSD	GDSC	56.683	Gain
CAMK_CAMKL_AMPK_PRKAA1_ST	P19429	TNNI3	Q13131	PRKAA1	T119	T119N	119	Missense	central	0	yes	58.629	0.000	EPSD	GDSC;CCLE	56.683	Loss
CAMK_CAMKL_AMPK_PRKAA1_ST	Q14457	BECN1	Q13131	PRKAA1	S104	M109I	109	Missense	distal	5	no	57.919	58.027	EPSD	GDSC;CCLE	56.683	Up-regulation
CAMK_CAMKL_AMPK_PRKAA1_ST	Q14457	BECN1	Q13131	PRKAA1	T108	M109I	109	Missense	proximal	1	no	59.691	56.069	EPSD	GDSC;CCLE	56.683	Loss
CAMK_CAMKL_AMPK_PRKAA1_ST	Q8N122	RPTOR	Q13131	PRKAA1	S721	R716I	716	Missense	distal	-5	no	59.616	61.372	EPSD	GDSC;CCLE	56.683	Up-regulation
CAMK_CAMKL_AMPK_PRKAA1_ST	Q8N122	RPTOR	Q13131	PRKAA1	S721	R718H	718	Missense	distal	-3	no	59.616	51.760	EPSD	GDSC;CCLE	56.683	Loss
CAMK_CAMKL_AMPK_PRKAA1_ST	Q8N122	RPTOR	Q13131	PRKAA1	S722	R716I	716	Missense	distal	-6	no	64.569	61.424	EPSD;PhosphoSitePlus	GDSC;CCLE	56.683	Down-regulation
CAMK_CAMKL_AMPK_PRKAA1_ST	Q8N122	RPTOR	Q13131	PRKAA1	S722	R718H	718	Missense	distal	-4	no	64.569	61.182	EPSD;PhosphoSitePlus	GDSC;CCLE	56.683	Down-regulation
CAMK_CAMKL_AMPK_PRKAA1_ST	Q8N122	RPTOR	Q13131	PRKAA1	T731	S734N	734	Missense	distal	3	no	59.290	61.283	EPSD	GDSC;CCLE	56.683	Up-regulation
CAMK_CAMKL_AMPK_PRKAA1_ST	Q8N122	RPTOR	Q13131	PRKAA1	S791	S798P	798	Missense	distal	7	no	62.734	62.236	EPSD	GDSC	56.683	Down-regulation
CAMK_CAMKL_AMPK_PRKAA1_ST	Q8N122	RPTOR	Q13131	PRKAA1	S792	S798P	798	Missense	distal	6	no	68.942	68.926	PhosphoSitePlus;EPSD	GDSC	56.683	Down-regulation
CAMK_CAMKL_AMPK_PRKAA1_ST	Q8N122	RPTOR	Q13131	PRKAA1	S794	S798P	798	Missense	distal	4	no	60.973	60.821	EPSD	GDSC	56.683	Down-regulation
CAMK_CAMKL_AMPK_PRKAA1_ST	Q13621	SLC12A1	Q13131	PRKAA1	S130	P124S	124	Missense	distal	-6	no	62.602	62.252	PhosphoSitePlus	GDSC;CCLE	56.683	Down-regulation
CAMK_CAMKL_AMPK_PRKAA1_ST	Q13621	SLC12A1	Q13131	PRKAA1	S130	Q137K	137	Missense	distal	7	no	62.602	60.352	PhosphoSitePlus	GDSC;CCLE	56.683	Down-regulation
CAMK_CAMKL_AMPK_PRKAA1_ST	Q13621	SLC12A1	Q13131	PRKAA1	S1003	H1001Q	1001	Missense	proximal	-2	no	56.970	60.153	EPSD	GDSC;CCLE	56.683	Up-regulation
CAMK_CAMKL_AMPK_PRKAA1_ST	Q13621	SLC12A1	Q13131	PRKAA1	S1003	P997L	997	Missense	distal	-6	no	56.970	56.930	EPSD	GDSC	56.683	Down-regulation
CAMK_CAMKL_AMPK_PRKAA1_ST	Q13621	SLC12A1	Q13131	PRKAA1	S1003	A1010V	1010	Missense	distal	7	no	56.970	54.551	EPSD	GDSC	56.683	Loss
CAMK_CAMKL_AMPK_PRKAA1_ST	Q13621	SLC12A1	Q13131	PRKAA1	S1003	R999S	999	Missense	distal	-4	no	56.970	55.905	EPSD	GDSC;CCLE	56.683	Loss
CAMK_CAMKL_AMPK_PRKAA1_ST	O75925	PIAS1	Q13131	PRKAA1	T71	R64L	64	Missense	distal	-7	no	59.434	58.002	EPSD	GDSC;CCLE	56.683	Down-regulation
CAMK_CAMKL_AMPK_PRKAA1_ST	O75925	PIAS1	Q13131	PRKAA1	S510	V505A	505	Missense	distal	-5	no	64.495	65.688	PhosphoSitePlus	GDSC;CCLE	56.683	Up-regulation
CAMK_CAMKL_AMPK_PRKAA1_ST	Q13362	PPP2R5C	Q13131	PRKAA1	S298	E301*	301	Missense	distal	3	no	59.027	58.674	PhosphoSitePlus;EPSD	GDSC	56.683	Down-regulation
CAMK_CAMKL_AMPK_PRKAA1_ST	Q13362	PPP2R5C	Q13131	PRKAA1	S497	R495L	495	Missense	proximal	-2	no	63.865	62.678	EPSD	GDSC	56.683	Down-regulation
CAMK_CAMKL_AMPK_PRKAA1_ST	P41235	HNF4A	Q13131	PRKAA1	S143	R136W	136	Missense	distal	-7	no	62.819	64.618	EPSD	GDSC	56.683	Up-regulation
CAMK_CAMKL_AMPK_PRKAA1_ST	P41235	HNF4A	Q13131	PRKAA1	T166	N173D	173	Missense	distal	7	no	65.932	64.411	EPSD	GDSC;CCLE	56.683	Down-regulation
CAMK_CAMKL_AMPK_PRKAA1_ST	P41235	HNF4A	Q13131	PRKAA1	S170	N173D	173	Missense	distal	3	no	56.727	55.474	EPSD	GDSC;CCLE	56.683	Loss
CAMK_CAMKL_AMPK_PRKAA1_ST	P41235	HNF4A	Q13131	PRKAA1	S303	R310Q	310	Missense	distal	7	no	58.110	59.474	EPSD	GDSC;CCLE	56.683	Up-regulation
CAMK_CAMKL_AMPK_PRKAA1_ST	P41235	HNF4A	Q13131	PRKAA1	S313	R312H	312	Missense	proximal	-1	no	57.846	57.865	PhosphoSitePlus	GDSC;CCLE	56.683	Up-regulation
CAMK_CAMKL_AMPK_PRKAA1_ST	P41235	HNF4A	Q13131	PRKAA1	S313	R310Q	310	Missense	distal	-3	no	57.846	49.901	PhosphoSitePlus	GDSC;CCLE	56.683	Loss
CAMK_CAMKL_AMPK_PRKAA1_ST	P49674	CSNK1E	Q13131	PRKAA1	S368	R365T	365	Missense	distal	-3	no	60.311	46.200	EPSD	GDSC;CCLE	56.683	Loss
CAMK_CAMKL_AMPK_PRKAA1_ST	P49674	CSNK1E	Q13131	PRKAA1	S368	P364S	364	Missense	distal	-4	no	60.311	61.554	EPSD	GDSC;CCLE	56.683	Up-regulation
CAMK_CAMKL_AMPK_PRKAA1_ST	P49674	CSNK1E	Q13131	PRKAA1	S377	A384V	384	Missense	distal	7	no	60.788	58.369	EPSD	GDSC;CCLE	56.683	Down-regulation
CAMK_CAMKL_AMPK_PRKAA1_ST	P49674	CSNK1E	Q13131	PRKAA1	S389	A384V	384	Missense	distal	-5	no	66.528	65.336	PhosphoSitePlus	GDSC;CCLE	56.683	Down-regulation
CAMK_CAMKL_AMPK_PRKAA1_ST	P49674	CSNK1E	Q13131	PRKAA1	S389	V388I	388	Missense	proximal	-1	no	66.528	66.612	PhosphoSitePlus	GDSC;CCLE	56.683	Up-regulation
CAMK_CAMKL_AMPK_PRKAA1_ST	P49674	CSNK1E	Q13131	PRKAA1	S390	A384V	384	Missense	distal	-6	no	63.455	61.604	EPSD	GDSC;CCLE	56.683	Down-regulation
CAMK_CAMKL_AMPK_PRKAA1_ST	P49674	CSNK1E	Q13131	PRKAA1	S390	V388I	388	Missense	proximal	-2	no	63.455	61.570	EPSD	GDSC;CCLE	56.683	Down-regulation
CAMK_CAMKL_AMPK_PRKAA1_ST	P49674	CSNK1E	Q13131	PRKAA1	S391	A384V	384	Missense	distal	-7	no	55.516	56.841	EPSD	GDSC;CCLE	56.683	Gain
CAMK_CAMKL_AMPK_PRKAA1_ST	P04626	ERBB2	Q13131	PRKAA1	S1051	R1048C	1048	Missense	distal	-3	no	60.932	46.784	EPSD	GDSC;CCLE	56.683	Loss
CAMK_CAMKL_AMPK_PRKAA1_ST	Q14694	USP10	Q13131	PRKAA1	S35	S28L	28	Missense	distal	-7	no	68.183	65.755	EPSD	GDSC;CCLE	56.683	Down-regulation
CAMK_CAMKL_AMPK_PRKAA1_ST	P22460	KCNA5	Q13131	PRKAA1	S559	S557R	557	Missense	proximal	-2	no	57.162	55.923	PhosphoSitePlus	GDSC;CCLE	56.683	Loss
CAMK_CAMKL_AMPK_PRKAA1_ST	O15360	FANCA	Q13131	PRKAA1	S73	S75G	75	Missense	proximal	2	no	60.311	59.802	EPSD	GDSC;CCLE	56.683	Down-regulation
CAMK_CAMKL_AMPK_PRKAA1_ST	O15360	FANCA	Q13131	PRKAA1	S347	R350W	350	Missense	distal	3	no	62.410	64.468	PhosphoSitePlus	GDSC;CCLE	56.683	Up-regulation
CAMK_CAMKL_AMPK_PRKAA1_ST	O95239	KIF4A	Q13131	PRKAA1	S894	T893P	893	Missense	proximal	-1	no	60.543	60.555	EPSD	GDSC;CCLE	56.683	Up-regulation
CAMK_CAMKL_AMPK_PRKAA1_ST	O95239	KIF4A	Q13131	PRKAA1	S1048	D1043N	1043	Missense	distal	-5	no	58.577	44.501	EPSD	GDSC;CCLE	56.683	Loss
CAMK_CAMKL_AMPK_PRKAA1_ST	O95239	KIF4A	Q13131	PRKAA1	S1186	D1189V	1189	Missense	distal	3	no	58.170	58.326	EPSD	GDSC	56.683	Up-regulation
CAMK_CAMKL_AMPK_PRKAA1_ST	O75385	ULK1	Q13131	PRKAA1	S304	T309P	309	Missense	distal	5	no	62.291	62.284	EPSD	GDSC	56.683	Down-regulation
CAMK_CAMKL_AMPK_PRKAA1_ST	O75385	ULK1	Q13131	PRKAA1	S304	G301S	301	Missense	distal	-3	no	62.291	61.931	EPSD	GDSC;CCLE	56.683	Down-regulation
CAMK_CAMKL_AMPK_PRKAA1_ST	O75385	ULK1	Q13131	PRKAA1	S304	S310P	310	Missense	distal	6	no	62.291	62.276	EPSD	GDSC	56.683	Down-regulation
CAMK_CAMKL_AMPK_PRKAA1_ST	O75385	ULK1	Q13131	PRKAA1	S317	S310P	310	Missense	distal	-7	no	64.086	61.819	EPSD	GDSC	56.683	Down-regulation
CAMK_CAMKL_AMPK_PRKAA1_ST	O75385	ULK1	Q13131	PRKAA1	S424	A418T	418	Missense	distal	-6	no	57.223	57.020	EPSD	GDSC	56.683	Down-regulation
CAMK_CAMKL_AMPK_PRKAA1_ST	O75385	ULK1	Q13131	PRKAA1	S424	C426R	426	Missense	proximal	2	no	57.223	58.614	EPSD	GDSC;CCLE	56.683	Up-regulation
CAMK_CAMKL_AMPK_PRKAA1_ST	O75385	ULK1	Q13131	PRKAA1	S429	C426R	426	Missense	distal	-3	no	46.504	60.651	EPSD	GDSC;CCLE	56.683	Gain
CAMK_CAMKL_AMPK_PRKAA1_ST	O75385	ULK1	Q13131	PRKAA1	S495	V489I	489	Missense	distal	-6	no	66.399	64.908	EPSD	GDSC;CCLE	56.683	Down-regulation
CAMK_CAMKL_AMPK_PRKAA1_ST	O75385	ULK1	Q13131	PRKAA1	S556	L550P	550	Missense	distal	-6	no	75.749	75.789	EPSD	GDSC	56.683	Up-regulation
CAMK_CAMKL_AMPK_PRKAA1_ST	O75385	ULK1	Q13131	PRKAA1	S556	N559K	559	Missense	distal	3	no	75.749	74.511	EPSD	GDSC;CCLE	56.683	Down-regulation
CAMK_CAMKL_AMPK_PRKAA1_ST	O75385	ULK1	Q13131	PRKAA1	S638	Q640K	640	Missense	proximal	2	no	63.868	64.461	PhosphoSitePlus	GDSC;CCLE	56.683	Up-regulation
CAMK_CAMKL_AMPK_PRKAA1_ST	O75385	ULK1	Q13131	PRKAA1	S694	R697H	697	Missense	distal	3	no	59.634	56.066	EPSD	GDSC;CCLE	56.683	Loss
CAMK_CAMKL_AMPK_PRKAA1_ST	O75385	ULK1	Q13131	PRKAA1	S694	D700G	700	Missense	distal	6	no	59.634	59.706	EPSD	GDSC;CCLE	56.683	Up-regulation
CAMK_CAMKL_AMPK_PRKAA1_ST	O75385	ULK1	Q13131	PRKAA1	S694	R691Q	691	Missense	distal	-3	no	59.634	51.690	EPSD	GDSC	56.683	Loss
CAMK_CAMKL_AMPK_PRKAA1_ST	O75385	ULK1	Q13131	PRKAA1	S696	R697H	697	Missense	proximal	1	no	54.049	57.047	EPSD	GDSC;CCLE	56.683	Gain
CAMK_CAMKL_AMPK_PRKAA1_ST	Q05469	LIPE	Q13131	PRKAA1	S200	G205R	205	Missense	distal	5	no	63.427	63.506	EPSD	GDSC;CCLE	56.683	Up-regulation
CAMK_CAMKL_AMPK_PRKAA1_ST	Q05469	LIPE	Q13131	PRKAA1	T202	G205R	205	Missense	distal	3	no	56.926	55.073	EPSD	GDSC;CCLE	56.683	Loss
CAMK_CAMKL_AMPK_PRKAA1_ST	Q05469	LIPE	Q13131	PRKAA1	T202	T208I	208	Missense	distal	6	no	56.926	56.670	EPSD	GDSC;CCLE	56.683	Loss
CAMK_CAMKL_AMPK_PRKAA1_ST	Q05469	LIPE	Q13131	PRKAA1	S218	I215K	215	Missense	distal	-3	no	50.783	59.541	EPSD	GDSC;CCLE	56.683	Gain
CAMK_CAMKL_AMPK_PRKAA1_ST	Q05469	LIPE	Q13131	PRKAA1	S621	E617Q	617	Missense	distal	-4	no	56.754	55.340	EPSD	GDSC	56.683	Loss
CAMK_CAMKL_AMPK_PRKAA1_ST	Q05469	LIPE	Q13131	PRKAA1	S621	S616G	616	Missense	distal	-5	no	56.754	56.751	EPSD	GDSC	56.683	Down-regulation
CAMK_CAMKL_AMPK_PRKAA1_ST	Q05469	LIPE	Q13131	PRKAA1	S855	S855F	855	Missense	central	0	yes	68.178	0.000	PhosphoSitePlus	GDSC;CCLE	56.683	Loss
CAMK_CAMKL_AMPK_PRKAA1_ST	Q05469	LIPE	Q13131	PRKAA1	S855	P862R	862	Missense	distal	7	no	68.178	68.090	PhosphoSitePlus	GDSC;CCLE	56.683	Down-regulation
CAMK_CAMKL_AMPK_PRKAA1_ST	Q6N021	TET2	Q13131	PRKAA1	S99	R96H	96	Missense	distal	-3	no	59.609	51.753	PhosphoSitePlus	GDSC;CCLE	56.683	Loss
CAMK_CAMKL_AMPK_PRKAA1_ST	Q6N021	TET2	Q13131	PRKAA1	S315	F316Y	316	Missense	proximal	1	no	58.201	55.977	EPSD	GDSC	56.683	Loss
CAMK_CAMKL_AMPK_PRKAA1_ST	Q6N021	TET2	Q13131	PRKAA1	S585	R581H	581	Missense	distal	-4	no	62.930	59.544	EPSD	GDSC;CCLE	56.683	Down-regulation
CAMK_CAMKL_AMPK_PRKAA1_ST	Q6N021	TET2	Q13131	PRKAA1	S1449	A1443S	1443	Missense	distal	-6	no	64.294	63.624	EPSD	GDSC;CCLE	56.683	Down-regulation
CAMK_CAMKL_AMPK_PRKAA1_ST	Q86TI0	TBC1D1	Q13131	PRKAA1	S407	E403Q	403	Missense	distal	-4	no	57.512	56.098	EPSD	GDSC;CCLE	56.683	Loss
CAMK_CAMKL_AMPK_PRKAA1_ST	Q9H3M7	TXNIP	Q13131	PRKAA1	S304	G301D	301	Missense	distal	-3	no	62.361	61.543	EPSD	GDSC;CCLE	56.683	Down-regulation
CAMK_CAMKL_AMPK_PRKAA1_ST	Q9H3M7	TXNIP	Q13131	PRKAA1	S308	G301D	301	Missense	distal	-7	no	62.136	60.832	PhosphoSitePlus	GDSC;CCLE	56.683	Down-regulation
CAMK_CAMKL_AMPK_PRKAA1_ST	Q9H3M7	TXNIP	Q13131	PRKAA1	S361	D360N	360	Missense	proximal	-1	no	58.179	58.139	EPSD	GDSC	56.683	Down-regulation
CAMK_CAMKL_AMPK_PRKAA1_ST	Q00613	HSF1	Q13131	PRKAA1	T120	N114S	114	Missense	distal	-6	no	65.215	65.094	EPSD	GDSC;CCLE	56.683	Down-regulation
CAMK_CAMKL_AMPK_PRKAA1_ST	Q00613	HSF1	Q13131	PRKAA1	S121	N114S	114	Missense	distal	-7	no	61.132	62.223	PhosphoSitePlus	GDSC;CCLE	56.683	Up-regulation
CAMK_CAMKL_AMPK_PRKAA1_ST	Q00613	HSF1	Q13131	PRKAA1	S290	R296H	296	Missense	distal	6	no	68.858	68.963	EPSD	GDSC;CCLE	56.683	Up-regulation
CAMK_CAMKL_AMPK_PRKAA1_ST	Q00613	HSF1	Q13131	PRKAA1	S363	R360Q	360	Missense	distal	-3	no	58.558	50.614	EPSD	GDSC	56.683	Loss
CAMK_CAMKL_AMPK_PRKAA1_ST	Q00613	HSF1	Q13131	PRKAA1	S363	R360W	360	Missense	distal	-3	no	58.558	-34.442	EPSD	GDSC;CCLE	56.683	Loss
CAMK_CAMKL_AMPK_PRKAA1_ST	Q00613	HSF1	Q13131	PRKAA1	S498	E502K	502	Missense	distal	4	no	51.559	57.315	EPSD	GDSC	56.683	Gain
CAMK_CAMKL_AMPK_PRKAA1_ST	Q16875	PFKFB3	Q13131	PRKAA1	S83	Q81H	81	Missense	proximal	-2	no	66.571	63.388	EPSD	GDSC;CCLE	56.683	Down-regulation
CAMK_CAMKL_AMPK_PRKAA1_ST	P14859	POU2F1	Q13131	PRKAA1	S78	S81L	81	Missense	distal	3	no	57.356	55.374	EPSD	GDSC	56.683	Loss
CAMK_CAMKL_AMPK_PRKAA1_ST	Q14247	CTTN	Q13131	PRKAA1	S113	V115A	115	Missense	proximal	2	no	59.382	58.236	EPSD	GDSC;CCLE	56.683	Down-regulation
CAMK_CAMKL_AMPK_PRKAA1_ST	P15056	BRAF	Q13131	PRKAA1	S151	R146Q	146	Missense	distal	-5	no	59.762	54.080	EPSD	GDSC;CCLE	56.683	Loss
CAMK_CAMKL_AMPK_PRKAA1_ST	P15056	BRAF	Q13131	PRKAA1	S363	D361G	361	Missense	proximal	-2	no	60.159	58.566	EPSD	GDSC;CCLE	56.683	Down-regulation
CAMK_CAMKL_AMPK_PRKAA1_ST	P15056	BRAF	Q13131	PRKAA1	S365	D361G	361	Missense	distal	-4	no	71.119	67.605	EPSD	GDSC;CCLE	56.683	Down-regulation
CAMK_CAMKL_AMPK_PRKAA1_ST	O14929	HAT1	Q13131	PRKAA1	S301	L305I	305	Missense	distal	4	no	61.163	58.087	EPSD	GDSC;CCLE	56.683	Down-regulation
CAMK_CAMKL_AMPK_PRKAA1_ST	Q12778	FOXO1	Q13131	PRKAA1	S218	L219P	219	Missense	proximal	1	no	57.131	57.424	EPSD	GDSC;CCLE	56.683	Up-regulation
CAMK_CAMKL_AMPK_PRKAA1_ST	Q12778	FOXO1	Q13131	PRKAA1	S218	I213S	213	Missense	distal	-5	no	57.131	52.370	EPSD	GDSC;CCLE	56.683	Loss
CAMK_CAMKL_AMPK_PRKAA1_ST	Q12778	FOXO1	Q13131	PRKAA1	S329	T333A	333	Missense	distal	4	no	59.724	62.292	EPSD	GDSC;CCLE	56.683	Up-regulation
CAMK_CAMKL_AMPK_PRKAA1_ST	Q12778	FOXO1	Q13131	PRKAA1	T333	T333A	333	Missense	central	0	yes	60.509	0.000	EPSD	GDSC;CCLE	56.683	Loss
CAMK_CAMKL_AMPK_PRKAA1_ST	P43405	SYK	Q13131	PRKAA1	S316	E315K	315	Missense	proximal	-1	no	59.006	58.980	EPSD	GDSC;CCLE	56.683	Down-regulation
CAMK_CAMKL_AMPK_PRKAA1_ST	Q9NR19	ACSS2	Q13131	PRKAA1	S659	R665P	665	Missense	distal	6	no	60.751	60.842	PhosphoSitePlus	GDSC;CCLE	56.683	Up-regulation
CAMK_CAMKL_AMPK_PRKAA1_ST	O00763	ACACB	Q13131	PRKAA1	S37	P43L	43	Missense	distal	6	no	68.031	68.180	EPSD	GDSC	56.683	Up-regulation
CAMK_CAMKL_AMPK_PRKAA1_ST	O00763	ACACB	Q13131	PRKAA1	S192	R189Q	189	Missense	distal	-3	no	59.804	51.859	EPSD	GDSC	56.683	Loss
CAMK_CAMKL_AMPK_PRKAA1_ST	O00763	ACACB	Q13131	PRKAA1	S1557	E1564Q	1564	Missense	distal	7	no	67.527	69.081	EPSD	GDSC;CCLE	56.683	Up-regulation
CAMK_CAMKL_AMPK_PRKAA1_ST	O00763	ACACB	Q13131	PRKAA1	T1641	A1644V	1644	Missense	distal	3	no	54.868	59.744	EPSD	GDSC;CCLE	56.683	Gain
CAMK_CAMKL_AMPK_PRKAA1_ST	Q13501	SQSTM1	Q13131	PRKAA1	S180	S180*	180	Missense	central	0	yes	57.331	0.000	EPSD	GDSC	56.683	Loss
CAMK_CAMKL_AMPK_PRKAA1_ST	Q13501	SQSTM1	Q13131	PRKAA1	S349	L356P	356	Missense	distal	7	no	61.532	60.992	EPSD	GDSC;CCLE	56.683	Down-regulation
CAMK_CAMKL_AMPK_PRKAA1_ST	Q13501	SQSTM1	Q13131	PRKAA1	S349	Q354*	354	Missense	distal	5	no	61.532	61.345	EPSD	GDSC	56.683	Down-regulation
CMGC_CDK_CRK7_CDK12_ST	P24928	POLR2A	Q9NYV4	CDK12	T368	I367T	367	Missense	proximal	-1	no	4.124	4.107	EPSD	GDSC;CCLE	0.929	Down-regulation
CMGC_CDK_CRK7_CDK12_ST	P24928	POLR2A	Q9NYV4	CDK12	T1568	P1569L	1569	Missense	proximal	1	no	5.189	0.309	EPSD	GDSC;CCLE	0.929	Loss
CMGC_CDK_CRK7_CDK12_ST	P24928	POLR2A	Q9NYV4	CDK12	S1571	P1569L	1569	Missense	proximal	-2	no	5.658	5.710	EPSD	GDSC;CCLE	0.929	Up-regulation
CMGC_CDK_CRK7_CDK12_ST	P24928	POLR2A	Q9NYV4	CDK12	S1571	T1568S	1568	Missense	distal	-3	no	5.658	5.656	EPSD	GDSC;CCLE	0.929	Down-regulation
CMGC_CDK_CRK7_CDK12_ST	P24928	POLR2A	Q9NYV4	CDK12	S1574	P1569L	1569	Missense	distal	-5	no	4.953	4.817	EPSD	GDSC;CCLE	0.929	Down-regulation
CMGC_CDK_CRK7_CDK12_ST	P24928	POLR2A	Q9NYV4	CDK12	S1574	T1568S	1568	Missense	distal	-6	no	4.953	4.954	EPSD	GDSC;CCLE	0.929	Up-regulation
CMGC_CDK_CRK7_CDK12_ST	P24928	POLR2A	Q9NYV4	CDK12	S1616	S1616F	1616	Missense	central	0	yes	4.346	0.000	PhosphoSitePlus;EPSD	GDSC;CCLE	0.929	Loss
CMGC_CDK_CRK7_CDK12_ST	P24928	POLR2A	Q9NYV4	CDK12	S1619	S1616F	1616	Missense	distal	-3	no	3.907	3.864	EPSD;PhosphoSitePlus	GDSC;CCLE	0.929	Down-regulation
CMGC_CDK_CRK7_CDK12_ST	P24928	POLR2A	Q9NYV4	CDK12	S1621	S1616F	1616	Missense	distal	-5	no	1.088	1.066	EPSD	GDSC;CCLE	0.929	Down-regulation
CMGC_CDK_CRK7_CDK12_ST	P24928	POLR2A	Q9NYV4	CDK12	S1766	P1764L	1764	Missense	proximal	-2	no	3.736	3.788	EPSD	GDSC;CCLE	0.929	Up-regulation
CMGC_CDK_CRK7_CDK12_ST	P24928	POLR2A	Q9NYV4	CDK12	S1850	Y1853H	1853	Missense	distal	3	no	3.936	3.939	EPSD	GDSC;CCLE	0.929	Up-regulation
CMGC_CDK_CRK7_CDK12_ST	P24928	POLR2A	Q9NYV4	CDK12	T1854	Y1853H	1853	Missense	proximal	-1	no	4.352	4.349	EPSD	GDSC;CCLE	0.929	Down-regulation
CMGC_CDK_CRK7_CDK12_ST	P24928	POLR2A	Q9NYV4	CDK12	S1857	P1862T	1862	Missense	distal	5	no	4.546	4.557	EPSD	GDSC;CCLE	0.929	Up-regulation
CMGC_CDK_CRK7_CDK12_ST	P24928	POLR2A	Q9NYV4	CDK12	S1857	Y1853H	1853	Missense	distal	-4	no	4.546	4.571	EPSD	GDSC;CCLE	0.929	Up-regulation
CMGC_CDK_CRK7_CDK12_ST	P24928	POLR2A	Q9NYV4	CDK12	S1861	P1862T	1862	Missense	proximal	1	no	4.330	0.144	EPSD	GDSC;CCLE	0.929	Loss
CMGC_CDK_CRK7_CDK12_ST	P24928	POLR2A	Q9NYV4	CDK12	S1864	P1862T	1862	Missense	proximal	-2	no	3.958	3.998	EPSD	GDSC;CCLE	0.929	Up-regulation
CMGC_CDK_CRK7_CDK12_ST	P24928	POLR2A	Q9NYV4	CDK12	S1868	P1862T	1862	Missense	distal	-6	no	4.193	4.170	EPSD	GDSC;CCLE	0.929	Down-regulation
CMGC_CDK_CRK7_CDK12_ST	P24928	POLR2A	Q9NYV4	CDK12	S1958	I1961V	1961	Missense	distal	3	no	4.711	4.709	EPSD	GDSC;CCLE	0.929	Down-regulation
CMGC_CDK_CRK7_CDK12_ST	P24928	POLR2A	Q9NYV4	CDK12	S1962	I1961V	1961	Missense	proximal	-1	no	4.400	4.389	EPSD	GDSC;CCLE	0.929	Down-regulation
CAMK_CAMK1_CAMK4_ST	Q9UQL6	HDAC5	Q16566	CAMK4	S1108	E1114Q	1114	Missense	distal	6	no	10.348	10.246	EPSD	GDSC	9.847	Down-regulation
CAMK_CAMK1_CAMK4_ST	P16220	CREB1	Q16566	CAMK4	S114	S111L	111	Missense	distal	-3	no	10.753	7.158	EPSD	GDSC;CCLE	9.847	Loss
CAMK_CAMK1_CAMK4_ST	P14866	HNRNPL	Q16566	CAMK4	S530	V532M	532	Missense	proximal	2	no	10.781	10.771	EPSD	GDSC;CCLE	9.847	Down-regulation
CAMK_CAMK1_CAMK4_ST	P14866	HNRNPL	Q16566	CAMK4	S531	V532M	532	Missense	proximal	1	no	12.818	12.887	EPSD	GDSC;CCLE	9.847	Up-regulation
CAMK_CAMK1_CAMK4_ST	P14866	HNRNPL	Q16566	CAMK4	S536	V532M	532	Missense	distal	-4	no	15.370	15.571	EPSD	GDSC;CCLE	9.847	Up-regulation
CAMK_CAMK1_CAMK4_ST	P14866	HNRNPL	Q16566	CAMK4	S539	V532M	532	Missense	distal	-7	no	10.787	10.706	EPSD	GDSC;CCLE	9.847	Down-regulation
CAMK_CAMK1_CAMK4_ST	Q99623	PHB2	Q16566	CAMK4	S91	G95V	95	Missense	distal	4	no	15.761	15.850	PhosphoSitePlus	GDSC;CCLE	9.847	Up-regulation
CAMK_CAMK1_CAMK4_ST	Q99623	PHB2	Q16566	CAMK4	S92	G95V	95	Missense	distal	3	no	12.195	12.172	EPSD	GDSC;CCLE	9.847	Down-regulation
CAMK_CAMK1_CAMK4_ST	Q99623	PHB2	Q16566	CAMK4	S96	G95V	95	Missense	proximal	-1	no	10.857	10.798	EPSD	GDSC;CCLE	9.847	Down-regulation
CAMK_CAMK1_CAMK4_ST	Q99623	PHB2	Q16566	CAMK4	T194	R191Q	191	Missense	distal	-3	no	10.549	5.867	EPSD	GDSC	9.847	Loss
CAMK_CAMK1_CAMK4_ST	Q99623	PHB2	Q16566	CAMK4	T194	Q201P	201	Missense	distal	7	no	10.549	9.578	EPSD	GDSC;CCLE	9.847	Loss
CAMK_CAMK1_CAMK4_ST	P16949	STMN1	Q16566	CAMK4	S16	E10K	10	Missense	distal	-6	no	14.860	15.056	PhosphoSitePlus	GDSC;CCLE	9.847	Up-regulation
CAMK_CAMK1_CAMK4_ST	P16949	STMN1	Q16566	CAMK4	S16	E10*	10	Missense	distal	-6	no	14.860	14.624	PhosphoSitePlus	GDSC	9.847	Down-regulation
CAMK_CAMKL_AMPK_PRKAA2_ST	P09874	PARP1	P54646	PRKAA2	S455	N450S	450	Missense	distal	-5	no	53.514	52.608	EPSD	GDSC	46.832	Down-regulation
CAMK_CAMKL_AMPK_PRKAA2_ST	O00418	EEF2K	P54646	PRKAA2	S66	Y69H	69	Missense	distal	3	no	46.464	50.446	EPSD	GDSC;CCLE	46.832	Gain
CAMK_CAMKL_AMPK_PRKAA2_ST	O00418	EEF2K	P54646	PRKAA2	S492	N490T	490	Missense	proximal	-2	no	56.130	55.424	EPSD	GDSC	46.832	Down-regulation
CAMK_CAMKL_AMPK_PRKAA2_ST	O00418	EEF2K	P54646	PRKAA2	S492	H495P	495	Missense	distal	3	no	56.130	54.197	EPSD	GDSC	46.832	Down-regulation
CAMK_CAMKL_AMPK_PRKAA2_ST	O00418	EEF2K	P54646	PRKAA2	S492	S491P	491	Missense	proximal	-1	no	56.130	55.827	EPSD	GDSC	46.832	Down-regulation
CAMK_CAMKL_AMPK_PRKAA2_ST	P28562	DUSP1	P54646	PRKAA2	S334	R331*	331	Missense	distal	-3	no	71.466	55.413	PhosphoSitePlus	GDSC	46.832	Down-regulation
CAMK_CAMKL_AMPK_PRKAA2_ST	P30260	CDC27	P54646	PRKAA2	S276	P280L	280	Missense	distal	4	no	43.178	51.511	EPSD	GDSC;CCLE	46.832	Gain
CAMK_CAMKL_AMPK_PRKAA2_ST	P30260	CDC27	P54646	PRKAA2	T279	P280L	280	Missense	proximal	1	no	51.368	51.485	EPSD	GDSC;CCLE	46.832	Up-regulation
CAMK_CAMKL_AMPK_PRKAA2_ST	P30260	CDC27	P54646	PRKAA2	T279	A274P	274	Missense	distal	-5	no	51.368	46.576	EPSD	GDSC	46.832	Loss
CAMK_CAMKL_AMPK_PRKAA2_ST	P30260	CDC27	P54646	PRKAA2	T279	S281R	281	Missense	proximal	2	no	51.368	48.241	EPSD	GDSC	46.832	Down-regulation
CAMK_CAMKL_AMPK_PRKAA2_ST	P30260	CDC27	P54646	PRKAA2	S296	P290Q	290	Missense	distal	-6	no	47.929	48.346	EPSD	GDSC	46.832	Up-regulation
CAMK_CAMKL_AMPK_PRKAA2_ST	O43524	FOXO3	P54646	PRKAA2	S253	R249W	249	Missense	distal	-4	no	51.904	49.837	EPSD	GDSC;CCLE	46.832	Down-regulation
CAMK_CAMKL_AMPK_PRKAA2_ST	O43524	FOXO3	P54646	PRKAA2	S315	V320I	320	Missense	distal	5	no	54.324	54.317	EPSD	GDSC;CCLE	46.832	Down-regulation
CAMK_CAMKL_AMPK_PRKAA2_ST	O43524	FOXO3	P54646	PRKAA2	T319	V320I	320	Missense	proximal	1	no	52.081	52.129	EPSD	GDSC;CCLE	46.832	Up-regulation
CAMK_CAMKL_AMPK_PRKAA2_ST	O43524	FOXO3	P54646	PRKAA2	S413	R410W	410	Missense	distal	-3	no	68.510	52.366	EPSD;PhosphoSitePlus	GDSC;CCLE	46.832	Down-regulation
CAMK_CAMKL_AMPK_PRKAA2_ST	O43524	FOXO3	P54646	PRKAA2	S413	M408V	408	Missense	distal	-5	no	68.510	62.908	EPSD;PhosphoSitePlus	GDSC;CCLE	46.832	Down-regulation
CAMK_CAMKL_AMPK_PRKAA2_ST	O43524	FOXO3	P54646	PRKAA2	S555	E561D	561	Missense	distal	6	no	66.106	65.497	EPSD;PhosphoSitePlus	GDSC	46.832	Down-regulation
CAMK_CAMKL_AMPK_PRKAA2_ST	P08151	GLI1	P54646	PRKAA2	S84	P87S	87	Missense	distal	3	no	47.664	51.401	EPSD	GDSC;CCLE	46.832	Up-regulation
CAMK_CAMKL_AMPK_PRKAA2_ST	P08151	GLI1	P54646	PRKAA2	S89	P87S	87	Missense	proximal	-2	no	54.351	53.780	EPSD	GDSC;CCLE	46.832	Down-regulation
CAMK_CAMKL_AMPK_PRKAA2_ST	P08151	GLI1	P54646	PRKAA2	S545	R542C	542	Missense	distal	-3	no	59.044	45.771	EPSD	GDSC;CCLE	46.832	Loss
CAMK_CAMKL_AMPK_PRKAA2_ST	P08151	GLI1	P54646	PRKAA2	S545	S545G	545	Missense	central	0	yes	59.044	0.000	EPSD	GDSC;CCLE	46.832	Loss
CAMK_CAMKL_AMPK_PRKAA2_ST	P08151	GLI1	P54646	PRKAA2	S937	V936I	936	Missense	proximal	-1	no	48.235	47.883	EPSD	GDSC;CCLE	46.832	Down-regulation
CAMK_CAMKL_AMPK_PRKAA2_ST	Q9BZL4	PPP1R12C	P54646	PRKAA2	S325	S327N	327	Missense	proximal	2	no	53.368	43.700	EPSD	GDSC;CCLE	46.832	Loss
CAMK_CAMKL_AMPK_PRKAA2_ST	Q9BZL4	PPP1R12C	P54646	PRKAA2	S399	G396D	396	Missense	distal	-3	no	54.644	59.494	EPSD	GDSC	46.832	Up-regulation
CAMK_CAMKL_AMPK_PRKAA2_ST	Q9BZL4	PPP1R12C	P54646	PRKAA2	S399	T393P	393	Missense	distal	-6	no	54.644	53.836	EPSD	GDSC	46.832	Down-regulation
CAMK_CAMKL_AMPK_PRKAA2_ST	Q9BZL4	PPP1R12C	P54646	PRKAA2	S559	R557Q	557	Missense	proximal	-2	no	49.854	46.530	EPSD	GDSC;CCLE	46.832	Loss
CAMK_CAMKL_AMPK_PRKAA2_ST	Q9BXM7	PINK1	P54646	PRKAA2	S495	R492*	492	Missense	distal	-3	no	68.340	52.286	EPSD;PhosphoSitePlus	GDSC	46.832	Down-regulation
CAMK_CAMKL_AMPK_PRKAA2_ST	Q92819	HAS2	P54646	PRKAA2	S334	R333P	333	Missense	proximal	-1	no	50.856	50.851	EPSD	GDSC;CCLE	46.832	Down-regulation
CAMK_CAMKL_AMPK_PRKAA2_ST	Q9UQB8	BAIAP2	P54646	PRKAA2	T360	K359R	359	Missense	proximal	-1	no	49.934	50.080	EPSD	GDSC;CCLE	46.832	Up-regulation
CAMK_CAMKL_AMPK_PRKAA2_ST	Q9UQB8	BAIAP2	P54646	PRKAA2	T360	T356I	356	Missense	distal	-4	no	49.934	49.357	EPSD	GDSC	46.832	Down-regulation
CAMK_CAMKL_AMPK_PRKAA2_ST	Q9UQB8	BAIAP2	P54646	PRKAA2	S366	K359R	359	Missense	distal	-7	no	65.938	65.639	PhosphoSitePlus	GDSC;CCLE	46.832	Down-regulation
CAMK_CAMKL_AMPK_PRKAA2_ST	Q13177	PAK2	P54646	PRKAA2	S19	A13S	13	Missense	distal	-6	no	48.254	49.650	EPSD	GDSC;CCLE	46.832	Up-regulation
CAMK_CAMKL_AMPK_PRKAA2_ST	Q13177	PAK2	P54646	PRKAA2	S20	A13S	13	Missense	distal	-7	no	62.155	62.273	PhosphoSitePlus	GDSC;CCLE	46.832	Up-regulation
CAMK_CAMKL_AMPK_PRKAA2_ST	Q13177	PAK2	P54646	PRKAA2	T238	I242T	242	Missense	distal	4	no	55.175	57.662	EPSD	GDSC;CCLE	46.832	Up-regulation
CAMK_CAMKL_AMPK_PRKAA2_ST	Q13177	PAK2	P54646	PRKAA2	S507	S508I	508	Missense	proximal	1	no	58.874	58.700	EPSD	GDSC;CCLE	46.832	Down-regulation
CAMK_CAMKL_AMPK_PRKAA2_ST	O14920	IKBKB	P54646	PRKAA2	S689	G685W	685	Missense	distal	-4	no	47.393	47.272	EPSD	GDSC;CCLE	46.832	Down-regulation
CAMK_CAMKL_AMPK_PRKAA2_ST	O14920	IKBKB	P54646	PRKAA2	S692	G685W	685	Missense	distal	-7	no	50.831	50.885	EPSD	GDSC;CCLE	46.832	Up-regulation
CAMK_CAMKL_AMPK_PRKAA2_ST	P05549	TFAP2A	P54646	PRKAA2	S219	L218F	218	Missense	proximal	-1	no	67.563	66.949	PhosphoSitePlus	GDSC;CCLE	46.832	Down-regulation
AGC_NDR_NDR_STK38L_ST	O60285	NUAK1	Q9Y2H1	STK38L	T211	S215I	215	Missense	distal	4	no	8.221	7.162	PhosphoSitePlus	GDSC;CCLE	2.379	Down-regulation
AGC_NDR_NDR_STK38L_ST	O60285	NUAK1	Q9Y2H1	STK38L	S444	A448V	448	Missense	distal	4	no	2.435	1.345	EPSD	GDSC	2.379	Loss
AGC_NDR_NDR_STK38L_ST	Q96QF0	RAB3IP	Q9Y2H1	STK38L	S154	D148G	148	Missense	distal	-6	no	3.223	3.216	EPSD	GDSC	2.379	Down-regulation
AGC_NDR_NDR_STK38L_ST	Q96QF0	RAB3IP	Q9Y2H1	STK38L	T257	S263F	263	Missense	distal	6	no	2.497	2.469	EPSD	GDSC	2.379	Down-regulation
AGC_NDR_NDR_STK38L_ST	Q96QF0	RAB3IP	Q9Y2H1	STK38L	T257	S262N	262	Missense	distal	5	no	2.497	2.666	EPSD	GDSC	2.379	Up-regulation
AGC_NDR_NDR_STK38L_ST	Q96QF0	RAB3IP	Q9Y2H1	STK38L	T257	V259A	259	Missense	proximal	2	no	2.497	2.341	EPSD	GDSC	2.379	Loss
AGC_NDR_NDR_STK38L_ST	Q96QF0	RAB3IP	Q9Y2H1	STK38L	S266	T265A	265	Missense	proximal	-1	no	2.583	2.811	EPSD	GDSC	2.379	Up-regulation
AGC_NDR_NDR_STK38L_ST	Q96QF0	RAB3IP	Q9Y2H1	STK38L	S266	S263F	263	Missense	distal	-3	no	2.583	2.737	EPSD	GDSC	2.379	Up-regulation
AGC_NDR_NDR_STK38L_ST	Q96QF0	RAB3IP	Q9Y2H1	STK38L	S266	S262N	262	Missense	distal	-4	no	2.583	2.515	EPSD	GDSC	2.379	Down-regulation
AGC_NDR_NDR_STK38L_ST	Q96QF0	RAB3IP	Q9Y2H1	STK38L	S266	V259A	259	Missense	distal	-7	no	2.583	2.584	EPSD	GDSC	2.379	Up-regulation
AGC_NDR_NDR_STK38L_ST	P46937	YAP1	Q9Y2H1	STK38L	S94	P98L	98	Missense	distal	4	no	4.182	4.348	EPSD	GDSC;CCLE	2.379	Up-regulation
AGC_NDR_NDR_STK38L_ST	P46937	YAP1	Q9Y2H1	STK38L	S105	P98L	98	Missense	distal	-7	no	3.816	3.817	EPSD	GDSC;CCLE	2.379	Up-regulation
AGC_NDR_NDR_STK38L_ST	P46937	YAP1	Q9Y2H1	STK38L	T154	R161*	161	Missense	distal	7	no	2.447	2.437	EPSD	GDSC	2.379	Down-regulation
AGC_NDR_NDR_STK38L_ST	P46937	YAP1	Q9Y2H1	STK38L	T378	D383A	383	Missense	distal	5	no	3.593	3.557	EPSD	GDSC;CCLE	2.379	Down-regulation
AGC_NDR_NDR_STK38L_ST	P46937	YAP1	Q9Y2H1	STK38L	T379	D383A	383	Missense	distal	4	no	2.065	3.139	EPSD	GDSC;CCLE	2.379	Gain
AGC_NDR_NDR_STK38L_ST	P46937	YAP1	Q9Y2H1	STK38L	S499	S499G	499	Missense	central	0	yes	2.920	0.000	EPSD	GDSC;CCLE	2.379	Loss
CK1_CK1_CK1-D_CSNK1E_ST	O15055	PER2	P49674	CSNK1E	S56	G62W	62	Missense	distal	6	no	22.846	20.582	EPSD	GDSC;CCLE	22.404	Loss
CK1_CK1_CK1-D_CSNK1E_ST	O15055	PER2	P49674	CSNK1E	S662	A664V	664	Missense	proximal	2	no	39.470	37.304	PhosphoSitePlus;EPSD	GDSC	22.404	Down-regulation
CK1_CK1_CK1-D_CSNK1E_ST	O15055	PER2	P49674	CSNK1E	S665	A664V	664	Missense	proximal	-1	no	39.530	31.862	EPSD;PhosphoSitePlus	GDSC	22.404	Down-regulation
CK1_CK1_CK1-D_CSNK1E_ST	O15055	PER2	P49674	CSNK1E	S668	A664V	664	Missense	distal	-4	no	35.036	29.635	EPSD;PhosphoSitePlus	GDSC	22.404	Down-regulation
CK1_CK1_CK1-D_CSNK1E_ST	O15055	PER2	P49674	CSNK1E	S810	G812E	812	Missense	proximal	2	no	25.780	27.212	EPSD	GDSC;CCLE	22.404	Up-regulation
CK1_CK1_CK1-D_CSNK1E_ST	O15055	PER2	P49674	CSNK1E	T1013	A1020T	1020	Missense	distal	7	no	27.830	27.938	EPSD	GDSC;CCLE	22.404	Up-regulation
CK1_CK1_CK1-D_CSNK1E_ST	O15055	PER2	P49674	CSNK1E	T1015	A1020T	1020	Missense	distal	5	no	27.017	26.469	EPSD	GDSC;CCLE	22.404	Down-regulation
CK1_CK1_CK1-D_CSNK1E_ST	Q92997	DVL3	P49674	CSNK1E	S125	D132G	132	Missense	distal	7	no	29.683	29.727	EPSD	GDSC	22.404	Up-regulation
CK1_CK1_CK1-D_CSNK1E_ST	Q92997	DVL3	P49674	CSNK1E	S137	D132G	132	Missense	distal	-5	no	29.116	29.658	EPSD	GDSC	22.404	Up-regulation
CK1_CK1_CK1-D_CSNK1E_ST	Q92997	DVL3	P49674	CSNK1E	S564	G561S	561	Missense	distal	-3	no	24.646	24.369	EPSD	GDSC;CCLE	22.404	Down-regulation
CK1_CK1_CK1-D_CSNK1E_ST	Q92997	DVL3	P49674	CSNK1E	S564	G562R	562	Missense	proximal	-2	no	24.646	19.939	EPSD	GDSC;CCLE	22.404	Loss
CK1_CK1_CK1-D_CSNK1E_ST	Q92997	DVL3	P49674	CSNK1E	S567	G561S	561	Missense	distal	-6	no	37.739	38.825	EPSD	GDSC;CCLE	22.404	Up-regulation
CK1_CK1_CK1-D_CSNK1E_ST	Q92997	DVL3	P49674	CSNK1E	S567	G562R	562	Missense	distal	-5	no	37.739	36.728	EPSD	GDSC;CCLE	22.404	Down-regulation
CK1_CK1_CK1-D_CSNK1E_ST	Q92997	DVL3	P49674	CSNK1E	S622	A629D	629	Missense	distal	7	no	23.100	22.817	EPSD	GDSC;CCLE	22.404	Down-regulation
CK1_CK1_CK1-D_CSNK1E_ST	Q92997	DVL3	P49674	CSNK1E	S633	A629D	629	Missense	distal	-4	no	23.284	20.619	EPSD;PhosphoSitePlus	GDSC;CCLE	22.404	Loss
CK1_CK1_CK1-D_CSNK1E_ST	Q92997	DVL3	P49674	CSNK1E	S636	A629D	629	Missense	distal	-7	no	26.308	26.309	EPSD;PhosphoSitePlus	GDSC;CCLE	22.404	Up-regulation
CK1_CK1_CK1-D_CSNK1E_ST	Q92997	DVL3	P49674	CSNK1E	S697	A696T	696	Missense	proximal	-1	no	30.413	24.638	EPSD	GDSC;CCLE	22.404	Down-regulation
CK1_CK1_CK1-D_CSNK1E_ST	Q92997	DVL3	P49674	CSNK1E	S697	R698T	698	Missense	proximal	1	no	30.413	30.534	EPSD	GDSC;CCLE	22.404	Up-regulation
CK1_CK1_CK1-D_CSNK1E_ST	O95863	SNAI1	P49674	CSNK1E	S104	S111L	111	Missense	distal	7	no	33.743	34.332	PhosphoSitePlus;EPSD	GDSC;CCLE	22.404	Up-regulation
CK1_CK1_CK1-D_CSNK1E_ST	O95863	SNAI1	P49674	CSNK1E	S107	S111L	111	Missense	distal	4	no	39.045	39.189	EPSD;PhosphoSitePlus	GDSC;CCLE	22.404	Up-regulation
CK1_CK1_CK1-D_CSNK1E_ST	Q8TD43	TRPM4	P49674	CSNK1E	S1098	S1102A	1102	Missense	distal	4	no	24.945	24.990	EPSD	GDSC;CCLE	22.404	Up-regulation
CK1_CK1_CK1-D_CSNK1E_ST	Q9Y6Q9	NCOA3	P49674	CSNK1E	S102	Q96R	96	Missense	distal	-6	no	34.349	33.892	PhosphoSitePlus	GDSC;CCLE	22.404	Down-regulation
CK1_CK1_CK1-D_CSNK1E_ST	Q9Y6Q9	NCOA3	P49674	CSNK1E	S652	S657F	657	Missense	distal	5	no	24.559	25.564	EPSD	GDSC;CCLE	22.404	Up-regulation
CK1_CK1_CK1-D_CSNK1E_ST	Q9Y6Q9	NCOA3	P49674	CSNK1E	S662	S657F	657	Missense	distal	-5	no	24.334	22.614	EPSD	GDSC;CCLE	22.404	Down-regulation
CK1_CK1_CK1-D_CSNK1E_ST	Q9Y6Q9	NCOA3	P49674	CSNK1E	S715	V721I	721	Missense	distal	6	no	25.096	26.695	EPSD	GDSC	22.404	Up-regulation
CK1_CK1_CK1-D_CSNK1E_ST	Q9Y6Q9	NCOA3	P49674	CSNK1E	S916	S917L	917	Missense	proximal	1	no	24.860	24.209	EPSD	GDSC	22.404	Down-regulation
CK1_CK1_CK1-D_CSNK1E_ST	P49674	CSNK1E	P49674	CSNK1E	S323	G318W	318	Missense	distal	-5	no	32.443	30.621	PhosphoSitePlus;EPSD	GDSC;CCLE	22.404	Down-regulation
CK1_CK1_CK1-D_CSNK1E_ST	P49674	CSNK1E	P49674	CSNK1E	T325	G318W	318	Missense	distal	-7	no	34.999	34.996	EPSD;PhosphoSitePlus	GDSC;CCLE	22.404	Down-regulation
CK1_CK1_CK1-D_CSNK1E_ST	P49674	CSNK1E	P49674	CSNK1E	S368	R365T	365	Missense	distal	-3	no	35.358	35.301	EPSD;PhosphoSitePlus	GDSC;CCLE	22.404	Down-regulation
CK1_CK1_CK1-D_CSNK1E_ST	P49674	CSNK1E	P49674	CSNK1E	S368	P364S	364	Missense	distal	-4	no	35.358	37.173	EPSD;PhosphoSitePlus	GDSC;CCLE	22.404	Up-regulation
CK1_CK1_CK1-D_CSNK1E_ST	P49674	CSNK1E	P49674	CSNK1E	S390	A384V	384	Missense	distal	-6	no	23.913	23.199	EPSD	GDSC;CCLE	22.404	Down-regulation
CK1_CK1_CK1-D_CSNK1E_ST	P49674	CSNK1E	P49674	CSNK1E	S390	V388I	388	Missense	proximal	-2	no	23.913	24.252	EPSD	GDSC;CCLE	22.404	Up-regulation
CK1_CK1_CK1-D_CSNK1E_ST	O14641	DVL2	P49674	CSNK1E	S131	G127S	127	Missense	distal	-4	no	21.828	26.115	EPSD	GDSC;CCLE	22.404	Gain
CK1_CK1_CK1-D_CSNK1E_ST	O14641	DVL2	P49674	CSNK1E	S591	R596Q	596	Missense	distal	5	no	27.923	26.392	EPSD	GDSC;CCLE	22.404	Down-regulation
CK1_CK1_CK1-D_CSNK1E_ST	O14641	DVL2	P49674	CSNK1E	S594	R596Q	596	Missense	proximal	2	no	27.965	29.798	EPSD	GDSC;CCLE	22.404	Up-regulation
CK1_CK1_CK1-D_CSNK1E_ST	O14641	DVL2	P49674	CSNK1E	S597	R596Q	596	Missense	proximal	-1	no	20.862	23.709	EPSD	GDSC;CCLE	22.404	Gain
CK1_CK1_CK1-D_CSNK1E_ST	Q13148	TARDBP	P49674	CSNK1E	S91	V96M	96	Missense	distal	5	no	22.843	21.633	EPSD	GDSC;CCLE	22.404	Loss
CK1_CK1_CK1-D_CSNK1E_ST	Q13148	TARDBP	P49674	CSNK1E	S92	V96M	96	Missense	distal	4	no	27.727	27.636	EPSD	GDSC;CCLE	22.404	Down-regulation
CK1_CK1_CK1-D_CSNK1E_ST	Q13148	TARDBP	P49674	CSNK1E	S389	A388V	388	Missense	proximal	-1	no	25.241	17.573	EPSD	GDSC;CCLE	22.404	Loss
CK1_CK1_CK1-D_CSNK1E_ST	Q13148	TARDBP	P49674	CSNK1E	S404	G400D	400	Missense	distal	-4	no	23.075	25.590	EPSD	GDSC;CCLE	22.404	Up-regulation
CK1_CK1_CK1-D_CSNK1E_ST	O75581	LRP6	P49674	CSNK1E	S122	I119V	119	Missense	distal	-3	no	27.140	24.664	EPSD	GDSC;CCLE	22.404	Down-regulation
CK1_CK1_CK1-D_CSNK1E_ST	O75581	LRP6	P49674	CSNK1E	S122	R118Q	118	Missense	distal	-4	no	27.140	28.891	EPSD	GDSC	22.404	Up-regulation
CK1_CK1_CK1-D_CSNK1E_ST	O75581	LRP6	P49674	CSNK1E	S1472	T1479I	1479	Missense	distal	7	no	35.188	34.995	EPSD	GDSC	22.404	Down-regulation
CK1_CK1_CK1-D_CSNK1E_ST	O75581	LRP6	P49674	CSNK1E	T1476	T1479I	1479	Missense	distal	3	no	25.298	26.439	EPSD	GDSC	22.404	Up-regulation
CK1_CK1_CK1-D_CSNK1E_ST	Q13114	TRAF3	P49674	CSNK1E	S349	V354L	354	Missense	distal	5	no	37.747	37.612	PhosphoSitePlus	GDSC;CCLE	22.404	Down-regulation
CK1_CK1_CK1-D_CSNK1E_ST	P25054	APC	P49674	CSNK1E	S102	S98I	98	Missense	distal	-4	no	29.973	25.634	EPSD	GDSC;CCLE	22.404	Down-regulation
CK1_CK1_CK1-D_CSNK1E_ST	P25054	APC	P49674	CSNK1E	S111	M115V	115	Missense	distal	4	no	23.480	23.571	EPSD	GDSC;CCLE	22.404	Up-regulation
CK1_CK1_CK1-D_CSNK1E_ST	P25054	APC	P49674	CSNK1E	S117	M115V	115	Missense	proximal	-2	no	20.865	23.163	EPSD	GDSC;CCLE	22.404	Gain
CK1_CK1_CK1-D_CSNK1E_ST	P25054	APC	P49674	CSNK1E	S296	R302*	302	Missense	distal	6	no	24.861	17.548	EPSD	GDSC	22.404	Loss
CK1_CK1_CK1-D_CSNK1E_ST	P25054	APC	P49674	CSNK1E	T1079	T1082S	1082	Missense	distal	3	no	18.856	23.995	EPSD	GDSC;CCLE	22.404	Gain
CK1_CK1_CK1-D_CSNK1E_ST	P25054	APC	P49674	CSNK1E	S1117	R1114*	1114	Missense	distal	-3	no	22.552	16.643	EPSD	GDSC	22.404	Loss
CK1_CK1_CK1-D_CSNK1E_ST	P25054	APC	P49674	CSNK1E	S1219	S1213P	1213	Missense	distal	-6	no	23.419	22.763	EPSD	GDSC;CCLE	22.404	Down-regulation
CK1_CK1_CK1-D_CSNK1E_ST	P25054	APC	P49674	CSNK1E	S1219	A1225S	1225	Missense	distal	6	no	23.419	27.118	EPSD	GDSC;CCLE	22.404	Up-regulation
CK1_CK1_CK1-D_CSNK1E_ST	P25054	APC	P49674	CSNK1E	S1219	E1216K	1216	Missense	distal	-3	no	23.419	24.509	EPSD	GDSC;CCLE	22.404	Up-regulation
CK1_CK1_CK1-D_CSNK1E_ST	P25054	APC	P49674	CSNK1E	S1340	Q1338*	1338	Missense	proximal	-2	no	23.203	13.213	EPSD	GDSC	22.404	Loss
CK1_CK1_CK1-D_CSNK1E_ST	P25054	APC	P49674	CSNK1E	S1340	S1344*	1344	Missense	distal	4	no	23.203	23.625	EPSD	GDSC	22.404	Up-regulation
CK1_CK1_CK1-D_CSNK1E_ST	P25054	APC	P49674	CSNK1E	S1340	G1339R	1339	Missense	proximal	-1	no	23.203	18.121	EPSD	GDSC;CCLE	22.404	Loss
CK1_CK1_CK1-D_CSNK1E_ST	P25054	APC	P49674	CSNK1E	S1344	Q1338*	1338	Missense	distal	-6	no	23.502	20.911	EPSD	GDSC	22.404	Loss
CK1_CK1_CK1-D_CSNK1E_ST	P25054	APC	P49674	CSNK1E	S1344	S1344*	1344	Missense	central	0	yes	23.502	0.000	EPSD	GDSC	22.404	Loss
CK1_CK1_CK1-D_CSNK1E_ST	P25054	APC	P49674	CSNK1E	S1344	G1339R	1339	Missense	distal	-5	no	23.502	22.491	EPSD	GDSC;CCLE	22.404	Down-regulation
CK1_CK1_CK1-D_CSNK1E_ST	P25054	APC	P49674	CSNK1E	T1368	Q1367*	1367	Missense	proximal	-1	no	27.840	15.558	EPSD	GDSC	22.404	Loss
CK1_CK1_CK1-D_CSNK1E_ST	P25054	APC	P49674	CSNK1E	S1389	S1392*	1392	Missense	distal	3	no	25.057	10.820	EPSD	GDSC	22.404	Loss
CK1_CK1_CK1-D_CSNK1E_ST	P25054	APC	P49674	CSNK1E	S1392	S1392*	1392	Missense	central	0	yes	34.913	0.000	EPSD;PhosphoSitePlus	GDSC	22.404	Loss
CK1_CK1_CK1-D_CSNK1E_ST	P25054	APC	P49674	CSNK1E	S1505	G1499*	1499	Missense	distal	-6	no	29.860	27.486	EPSD	GDSC	22.404	Down-regulation
CK1_CK1_CK1-D_CSNK1E_ST	P25054	APC	P49674	CSNK1E	S2110	N2109S	2109	Missense	proximal	-1	no	29.100	35.883	EPSD	GDSC	22.404	Up-regulation
CK1_CK1_CK1-D_CSNK1E_ST	P25054	APC	P49674	CSNK1E	S2241	K2248*	2248	Missense	distal	7	no	30.815	31.103	EPSD	GDSC	22.404	Up-regulation
CK1_CK1_CK1-D_CSNK1E_ST	P25054	APC	P49674	CSNK1E	S2244	K2248*	2248	Missense	distal	4	no	27.434	27.840	EPSD	GDSC	22.404	Up-regulation
CK1_CK1_CK1-D_CSNK1E_ST	P25054	APC	P49674	CSNK1E	T2266	S2262N	2262	Missense	distal	-4	no	23.530	17.996	EPSD	GDSC;CCLE	22.404	Loss
CK1_CK1_CK1-D_CSNK1E_ST	P25054	APC	P49674	CSNK1E	S2464	F2462S	2462	Missense	proximal	-2	no	27.851	35.888	EPSD	GDSC;CCLE	22.404	Up-regulation
CK1_CK1_CK1-D_CSNK1E_ST	P25054	APC	P49674	CSNK1E	S2464	P2467L	2467	Missense	distal	3	no	27.851	22.030	EPSD	GDSC;CCLE	22.404	Loss
CK1_CK1_CK1-D_CSNK1E_ST	P25054	APC	P49674	CSNK1E	S2473	P2467L	2467	Missense	distal	-6	no	31.375	30.751	EPSD	GDSC;CCLE	22.404	Down-regulation
CK1_CK1_CK1-D_CSNK1E_ST	P25054	APC	P49674	CSNK1E	T2546	W2547C	2547	Missense	proximal	1	no	24.642	25.149	EPSD	GDSC;CCLE	22.404	Up-regulation
CK1_CK1_CK1-D_CSNK1E_ST	P25054	APC	P49674	CSNK1E	T2563	V2561L	2561	Missense	proximal	-2	no	24.739	19.252	EPSD	GDSC;CCLE	22.404	Loss
CK1_CK1_CK1-D_CSNK1E_ST	P25054	APC	P49674	CSNK1E	S2569	S2575Y	2575	Missense	distal	6	no	23.725	19.496	EPSD	GDSC	22.404	Loss
CK1_CK1_CK1-D_CSNK1E_ST	P25054	APC	P49674	CSNK1E	S2577	S2575Y	2575	Missense	proximal	-2	no	25.007	19.472	EPSD	GDSC	22.404	Loss
CK1_CK1_CK1-D_CSNK1E_ST	P25054	APC	P49674	CSNK1E	S2580	S2575Y	2575	Missense	distal	-5	no	32.695	31.011	EPSD	GDSC	22.404	Down-regulation
CK1_CK1_CK1-D_CSNK1E_ST	P25054	APC	P49674	CSNK1E	S2674	R2673G	2673	Missense	proximal	-1	no	18.389	23.472	EPSD	GDSC;CCLE	22.404	Gain
CK1_CK1_CK1-D_CSNK1E_ST	P25054	APC	P49674	CSNK1E	S2687	V2686A	2686	Missense	proximal	-1	no	19.178	26.846	EPSD	GDSC;CCLE	22.404	Gain
CK1_CK1_CK1-D_CSNK1E_ST	P25054	APC	P49674	CSNK1E	S2772	A2778V	2778	Missense	distal	6	no	23.426	21.924	EPSD	GDSC	22.404	Loss
CK1_CK1_CK1-D_CSNK1E_ST	P25054	APC	P49674	CSNK1E	T2776	A2778V	2778	Missense	proximal	2	no	25.531	23.365	EPSD	GDSC	22.404	Down-regulation
CK1_CK1_CK1-D_CSNK1E_ST	P25054	APC	P49674	CSNK1E	T2828	H2834Y	2834	Missense	distal	6	no	26.711	24.539	EPSD	GDSC;CCLE	22.404	Down-regulation
CK1_CK1_CK1-D_CSNK1E_ST	P35222	CTNNB1	P49674	CSNK1E	T556	R549H	549	Missense	distal	-7	no	23.473	23.472	EPSD	GDSC;CCLE	22.404	Down-regulation
CK1_CK1_CK1-D_CSNK1E_ST	Q13541	EIF4EBP1	P49674	CSNK1E	T50	K57R	57	Missense	distal	7	no	32.732	32.495	EPSD;PhosphoSitePlus	GDSC	22.404	Down-regulation
CK1_CK1_CK1-D_CSNK1E_ST	Q9BZL6	PRKD2	P49674	CSNK1E	S43	Q50*	50	Missense	distal	7	no	22.985	23.407	EPSD	GDSC	22.404	Up-regulation
CK1_CK1_CK1-D_CSNK1E_ST	Q9BZL6	PRKD2	P49674	CSNK1E	S238	S245T	245	Missense	distal	7	no	29.192	29.743	EPSD	GDSC;CCLE	22.404	Up-regulation
CK1_CK1_CK1-D_CSNK1E_ST	Q9BZL6	PRKD2	P49674	CSNK1E	S239	S245T	245	Missense	distal	6	no	22.518	17.933	EPSD	GDSC;CCLE	22.404	Loss
CK1_CK1_CK1-D_CSNK1E_ST	Q9BZL6	PRKD2	P49674	CSNK1E	S241	S245T	245	Missense	distal	4	no	32.129	32.202	EPSD	GDSC;CCLE	22.404	Up-regulation
CK1_CK1_CK1-D_CSNK1E_ST	Q9BZL6	PRKD2	P49674	CSNK1E	S244	S245T	245	Missense	proximal	1	no	36.151	35.539	PhosphoSitePlus	GDSC;CCLE	22.404	Down-regulation
CK1_CK1_CK1-D_CSNK1E_ST	Q9BZL6	PRKD2	P49674	CSNK1E	S344	G348V	348	Missense	distal	4	no	22.484	22.483	EPSD	GDSC;CCLE	22.404	Down-regulation
CK1_CK1_CK1-D_CSNK1E_ST	Q9BZL6	PRKD2	P49674	CSNK1E	S347	G348V	348	Missense	proximal	1	no	22.533	23.196	EPSD	GDSC;CCLE	22.404	Up-regulation
CK1_CK1_CK1-D_CSNK1E_ST	Q9BZL6	PRKD2	P49674	CSNK1E	T714	A719S	719	Missense	distal	5	no	27.170	26.668	EPSD	GDSC;CCLE	22.404	Down-regulation
CK1_CK1_CK1-D_CSNK1E_ST	Q9BZL6	PRKD2	P49674	CSNK1E	T714	R708C	708	Missense	distal	-6	no	27.170	26.801	EPSD	GDSC;CCLE	22.404	Down-regulation
CK1_CK1_CK1-D_CSNK1E_ST	O60716	CTNND1	P49674	CSNK1E	T111	T113P	113	Missense	proximal	2	no	24.169	21.759	EPSD	GDSC	22.404	Loss
CK1_CK1_CK1-D_CSNK1E_ST	O60716	CTNND1	P49674	CSNK1E	T128	T133I	133	Missense	distal	5	no	21.448	22.487	EPSD	GDSC;CCLE	22.404	Gain
CK1_CK1_CK1-D_CSNK1E_ST	O60716	CTNND1	P49674	CSNK1E	S268	G267W	267	Missense	proximal	-1	no	44.781	34.886	PhosphoSitePlus	GDSC;CCLE	22.404	Down-regulation
CK1_CK1_CK1-D_CSNK1E_ST	O60716	CTNND1	P49674	CSNK1E	S861	R858Q	858	Missense	distal	-3	no	23.023	22.862	EPSD	GDSC	22.404	Down-regulation
CK1_CK1_CK1-D_CSNK1E_ST	O60353	FZD6	P49674	CSNK1E	S624	S624C	624	Missense	central	0	yes	31.668	0.000	EPSD	GDSC;CCLE	22.404	Loss
CAMK_CAMK1_CAMK1_ST	P46527	CDKN1B	Q14012	CAMK1	T157	P155L	155	Missense	proximal	-2	no	48.065	54.306	PhosphoSitePlus;EPSD	GDSC;CCLE	32.882	Up-regulation
CAMK_CAMK1_CAMK1_ST	P46527	CDKN1B	Q14012	CAMK1	T170	G177S	177	Missense	distal	7	no	43.298	43.317	EPSD	GDSC;CCLE	32.882	Up-regulation
CAMK_CAMK1_CAMK1_ST	Q9NP62	GCM1	Q14012	CAMK1	S47	I44T	44	Missense	distal	-3	no	46.907	36.897	PhosphoSitePlus	GDSC;CCLE	32.882	Down-regulation
CAMK_CAMK1_CAMK1_ST	Q9NP62	GCM1	Q14012	CAMK1	S269	R272*	272	Missense	distal	3	no	39.497	39.516	EPSD	GDSC	32.882	Up-regulation
CAMK_CAMK1_CAMK1_ST	O43432	EIF4G3	Q14012	CAMK1	T168	P169A	169	Missense	proximal	1	no	36.626	41.026	EPSD	GDSC;CCLE	32.882	Up-regulation
CAMK_CAMK1_CAMK1_ST	O43432	EIF4G3	Q14012	CAMK1	S176	P181L	181	Missense	distal	5	no	37.890	39.808	EPSD	GDSC;CCLE	32.882	Up-regulation
CAMK_CAMK1_CAMK1_ST	O43432	EIF4G3	Q14012	CAMK1	S176	P169A	169	Missense	distal	-7	no	37.890	38.233	EPSD	GDSC;CCLE	32.882	Up-regulation
CAMK_CAMK1_CAMK1_ST	O43432	EIF4G3	Q14012	CAMK1	S741	Q737K	737	Missense	distal	-4	no	39.711	39.899	EPSD	GDSC	32.882	Up-regulation
CAMK_CAMK1_CAMK1_ST	O43432	EIF4G3	Q14012	CAMK1	S741	P735Q	735	Missense	distal	-6	no	39.711	38.233	EPSD	GDSC	32.882	Down-regulation
CAMK_CAMK1_CAMK1_ST	O43432	EIF4G3	Q14012	CAMK1	S866	Q859H	859	Missense	distal	-7	no	38.565	38.544	EPSD	GDSC;CCLE	32.882	Down-regulation
CAMK_CAMK1_CAMK1_ST	O43432	EIF4G3	Q14012	CAMK1	T1127	G1130E	1130	Missense	distal	3	no	39.298	39.278	EPSD	GDSC;CCLE	32.882	Down-regulation
CAMK_CAMK1_CAMK1_ST	O43432	EIF4G3	Q14012	CAMK1	T1150	F1151S	1151	Missense	proximal	1	no	37.406	38.139	EPSD	GDSC;CCLE	32.882	Up-regulation
CAMK_CAMK1_CAMK1_ST	O43432	EIF4G3	Q14012	CAMK1	S1156	F1151S	1151	Missense	distal	-5	no	48.289	44.342	PhosphoSitePlus	GDSC;CCLE	32.882	Down-regulation
CAMK_CAMK1_CAMK1_ST	O43432	EIF4G3	Q14012	CAMK1	S1156	D1162V	1162	Missense	distal	6	no	48.289	48.404	PhosphoSitePlus	GDSC	32.882	Up-regulation
CAMK_CAMK1_CAMK1_ST	O43432	EIF4G3	Q14012	CAMK1	S1165	D1162V	1162	Missense	distal	-3	no	3.803	37.022	EPSD	GDSC	32.882	Gain
CAMK_CAMK1_CAMK1_ST	Q05469	LIPE	Q14012	CAMK1	S855	S855F	855	Missense	central	0	yes	51.500	0.000	PhosphoSitePlus	GDSC;CCLE	32.882	Loss
CAMK_CAMK1_CAMK1_ST	Q05469	LIPE	Q14012	CAMK1	S855	P862R	862	Missense	distal	7	no	51.500	50.932	PhosphoSitePlus	GDSC;CCLE	32.882	Down-regulation
CAMK_CAMK1_CAMK1_ST	Q9UQM7	CAMK2A	Q14012	CAMK1	S78	E82K	82	Missense	distal	4	no	32.651	33.122	EPSD	GDSC;CCLE	32.882	Gain
CAMK_CAMK1_CAMK1_ST	Q9UQM7	CAMK2A	Q14012	CAMK1	T276	W270*	270	Missense	distal	-6	no	40.965	41.120	EPSD	GDSC	32.882	Up-regulation
CAMK_CAMK1_CAMK1_ST	Q9Y570	PPME1	Q14012	CAMK1	S15	R12C	12	Missense	distal	-3	no	50.189	9.505	PhosphoSitePlus	GDSC	32.882	Loss
CAMK_CAMK1_CAMK1_ST	Q9Y570	PPME1	Q14012	CAMK1	S265	I268V	268	Missense	distal	3	no	33.108	33.121	EPSD	GDSC;CCLE	32.882	Up-regulation
CAMK_CAMK1_CAMK1_ST	Q9Y570	PPME1	Q14012	CAMK1	S265	E260V	260	Missense	distal	-5	no	33.108	33.893	EPSD	GDSC;CCLE	32.882	Up-regulation
TK_Src_SrcA_YES1_Y	P09917	ALOX5	P07947	YES1	Y446	A447S	447	Missense	proximal	1	no	20.656	18.696	EPSD;PhosphoSitePlus	GDSC	16.372	Down-regulation
TK_Src_SrcA_YES1_Y	Q05397	PTK2	P07947	YES1	Y407	T406I	406	Missense	proximal	-1	no	18.472	18.025	EPSD	GDSC;CCLE	16.372	Down-regulation
TK_Src_SrcA_YES1_Y	Q05397	PTK2	P07947	YES1	Y407	P410H	410	Missense	distal	3	no	18.472	15.620	EPSD	GDSC;CCLE	16.372	Loss
TK_Src_SrcA_YES1_Y	P04626	ERBB2	P07947	YES1	Y1005	S1007*	1007	Missense	proximal	2	no	17.646	17.355	EPSD	GDSC	16.372	Down-regulation
TK_Src_SrcA_YES1_Y	P04626	ERBB2	P07947	YES1	Y1248	V1253M	1253	Missense	distal	5	no	16.654	14.822	EPSD	GDSC;CCLE	16.372	Loss
TK_Src_SrcA_YES1_Y	Q969T9	WBP2	P07947	YES1	Y192	Q194K	194	Missense	proximal	2	no	34.604	34.842	EPSD;PhosphoSitePlus	GDSC	16.372	Up-regulation
TK_Src_SrcA_YES1_Y	Q969T9	WBP2	P07947	YES1	Y241	M242T	242	Missense	proximal	1	no	17.240	16.878	EPSD	GDSC;CCLE	16.372	Down-regulation
TK_Src_SrcA_YES1_Y	P46527	CDKN1B	P07947	YES1	Y88	E86K	86	Missense	proximal	-2	no	30.194	30.137	EPSD;PhosphoSitePlus	GDSC;CCLE	16.372	Down-regulation
TK_Src_SrcA_YES1_Y	P46527	CDKN1B	P07947	YES1	Y89	E86K	86	Missense	distal	-3	no	28.772	23.931	PhosphoSitePlus;EPSD	GDSC;CCLE	16.372	Down-regulation
Other_IKK_TBK1_ST	Q96FA3	PELI1	Q9UHD2	TBK1	T80	T86N	86	Missense	distal	6	no	178.443	181.177	PhosphoSitePlus;EPSD	GDSC;CCLE	145.681	Up-regulation
Other_IKK_TBK1_ST	Q96FA3	PELI1	Q9UHD2	TBK1	S82	T86N	86	Missense	distal	4	no	154.905	151.590	EPSD	GDSC;CCLE	145.681	Down-regulation
Other_IKK_TBK1_ST	Q96FA3	PELI1	Q9UHD2	TBK1	S125	D126A	126	Missense	proximal	1	no	148.101	139.008	EPSD	GDSC;CCLE	145.681	Loss
Other_IKK_TBK1_ST	Q96FA3	PELI1	Q9UHD2	TBK1	T288	P292S	292	Missense	distal	4	no	175.899	182.121	EPSD;PhosphoSitePlus	GDSC;CCLE	145.681	Up-regulation
Other_IKK_TBK1_ST	Q96FA3	PELI1	Q9UHD2	TBK1	S293	P292S	292	Missense	proximal	-1	no	183.079	182.676	EPSD;PhosphoSitePlus	GDSC;CCLE	145.681	Down-regulation
Other_IKK_TBK1_ST	Q13501	SQSTM1	Q9UHD2	TBK1	S182	S180*	180	Missense	proximal	-2	no	146.626	144.209	EPSD	GDSC	145.681	Loss
Other_IKK_TBK1_ST	Q13501	SQSTM1	Q9UHD2	TBK1	S266	T269A	269	Missense	distal	3	no	163.942	163.216	EPSD	GDSC;CCLE	145.681	Down-regulation
Other_IKK_TBK1_ST	Q13501	SQSTM1	Q9UHD2	TBK1	S272	T269A	269	Missense	distal	-3	no	160.990	160.198	EPSD	GDSC;CCLE	145.681	Down-regulation
Other_IKK_TBK1_ST	Q13501	SQSTM1	Q9UHD2	TBK1	S272	E274K	274	Missense	proximal	2	no	160.990	159.096	EPSD	GDSC;CCLE	145.681	Down-regulation
Other_IKK_TBK1_ST	Q13501	SQSTM1	Q9UHD2	TBK1	S275	T269A	269	Missense	distal	-6	no	154.122	153.127	EPSD	GDSC;CCLE	145.681	Down-regulation
Other_IKK_TBK1_ST	Q13501	SQSTM1	Q9UHD2	TBK1	S275	E274K	274	Missense	proximal	-1	no	154.122	154.983	EPSD	GDSC;CCLE	145.681	Up-regulation
Other_IKK_TBK1_ST	Q13501	SQSTM1	Q9UHD2	TBK1	S276	T269A	269	Missense	distal	-7	no	158.047	157.902	EPSD	GDSC;CCLE	145.681	Down-regulation
Other_IKK_TBK1_ST	Q13501	SQSTM1	Q9UHD2	TBK1	S276	E274K	274	Missense	proximal	-2	no	158.047	157.111	EPSD	GDSC;CCLE	145.681	Down-regulation
Other_IKK_TBK1_ST	Q13501	SQSTM1	Q9UHD2	TBK1	S355	L356P	356	Missense	proximal	1	no	155.173	148.103	EPSD	GDSC;CCLE	145.681	Down-regulation
Other_IKK_TBK1_ST	Q13501	SQSTM1	Q9UHD2	TBK1	S355	Q354*	354	Missense	proximal	-1	no	155.173	157.739	EPSD	GDSC	145.681	Up-regulation
Other_IKK_TBK1_ST	Q13501	SQSTM1	Q9UHD2	TBK1	S365	S370P	370	Missense	distal	5	no	156.094	155.423	EPSD	GDSC	145.681	Down-regulation
Other_IKK_TBK1_ST	Q13501	SQSTM1	Q9UHD2	TBK1	S366	S370P	370	Missense	distal	4	no	155.023	148.801	EPSD	GDSC	145.681	Down-regulation
Other_IKK_TBK1_ST	Q96CV9	OPTN	Q9UHD2	TBK1	S162	N169T	169	Missense	distal	7	no	148.195	148.130	EPSD	GDSC;CCLE	145.681	Down-regulation
Other_IKK_TBK1_ST	Q96CV9	OPTN	Q9UHD2	TBK1	S162	L166V	166	Missense	distal	4	no	148.195	153.549	EPSD	GDSC;CCLE	145.681	Up-regulation
Other_IKK_TBK1_ST	Q96CV9	OPTN	Q9UHD2	TBK1	S513	E516Q	516	Missense	distal	3	no	179.077	178.740	EPSD;PhosphoSitePlus	GDSC;CCLE	145.681	Down-regulation
Other_IKK_TBK1_ST	Q96CV9	OPTN	Q9UHD2	TBK1	S519	E516Q	516	Missense	distal	-3	no	150.700	154.650	EPSD	GDSC;CCLE	145.681	Up-regulation
Other_IKK_TBK1_ST	P23443	RPS6KB1	Q9UHD2	TBK1	S503	P505L	505	Missense	proximal	2	no	143.163	146.038	EPSD	GDSC	145.681	Gain
Other_IKK_TBK1_ST	Q8TEV9	SMCR8	Q9UHD2	TBK1	S465	M462V	462	Missense	distal	-3	no	149.808	151.039	EPSD	GDSC;CCLE	145.681	Up-regulation
Other_IKK_TBK1_ST	Q8TEV9	SMCR8	Q9UHD2	TBK1	S465	S468G	468	Missense	distal	3	no	149.808	151.402	EPSD	GDSC;CCLE	145.681	Up-regulation
Other_IKK_TBK1_ST	Q8TEV9	SMCR8	Q9UHD2	TBK1	S465	D461G	461	Missense	distal	-4	no	149.808	148.905	EPSD	GDSC;CCLE	145.681	Down-regulation
Other_IKK_TBK1_ST	Q8TEV9	SMCR8	Q9UHD2	TBK1	S467	M462V	462	Missense	distal	-5	no	160.327	160.432	EPSD	GDSC;CCLE	145.681	Up-regulation
Other_IKK_TBK1_ST	Q8TEV9	SMCR8	Q9UHD2	TBK1	S467	S468G	468	Missense	proximal	1	no	160.327	158.998	EPSD	GDSC;CCLE	145.681	Down-regulation
Other_IKK_TBK1_ST	Q8TEV9	SMCR8	Q9UHD2	TBK1	S467	D461G	461	Missense	distal	-6	no	160.327	146.264	EPSD	GDSC;CCLE	145.681	Down-regulation
Other_IKK_TBK1_ST	Q8TEV9	SMCR8	Q9UHD2	TBK1	S471	S468G	468	Missense	distal	-3	no	165.570	163.697	EPSD	GDSC;CCLE	145.681	Down-regulation
Other_IKK_TBK1_ST	Q8TEV9	SMCR8	Q9UHD2	TBK1	S516	T522P	522	Missense	distal	6	no	159.533	158.835	EPSD	GDSC	145.681	Down-regulation
Other_IKK_TBK1_ST	Q8TEV9	SMCR8	Q9UHD2	TBK1	S521	T522P	522	Missense	proximal	1	no	131.235	171.459	EPSD	GDSC	145.681	Gain
Other_IKK_TBK1_ST	Q8TEV9	SMCR8	Q9UHD2	TBK1	T796	T796P	796	Missense	central	0	yes	176.896	0.000	PhosphoSitePlus;EPSD	GDSC	145.681	Loss
Other_IKK_TBK1_ST	Q8TEV9	SMCR8	Q9UHD2	TBK1	T796	L800M	800	Missense	distal	4	no	176.896	178.009	PhosphoSitePlus;EPSD	GDSC;CCLE	145.681	Up-regulation
Other_IKK_TBK1_ST	Q14653	IRF3	Q9UHD2	TBK1	S385	T390A	390	Missense	distal	5	no	181.022	180.850	EPSD;PhosphoSitePlus	GDSC;CCLE	145.681	Down-regulation
Other_IKK_TBK1_ST	Q14653	IRF3	Q9UHD2	TBK1	S385	R380Q	380	Missense	distal	-5	no	181.022	182.304	EPSD;PhosphoSitePlus	GDSC;CCLE	145.681	Up-regulation
Other_IKK_TBK1_ST	Q14653	IRF3	Q9UHD2	TBK1	S386	T390A	390	Missense	distal	4	no	184.690	188.580	EPSD;PhosphoSitePlus	GDSC;CCLE	145.681	Up-regulation
Other_IKK_TBK1_ST	Q14653	IRF3	Q9UHD2	TBK1	S386	R380Q	380	Missense	distal	-6	no	184.690	190.837	EPSD;PhosphoSitePlus	GDSC;CCLE	145.681	Up-regulation
Other_IKK_TBK1_ST	Q14653	IRF3	Q9UHD2	TBK1	T390	T390A	390	Missense	central	0	yes	156.230	0.000	EPSD	GDSC;CCLE	145.681	Loss
Other_IKK_TBK1_ST	Q14653	IRF3	Q9UHD2	TBK1	S396	T390A	390	Missense	distal	-6	no	177.185	176.190	EPSD;PhosphoSitePlus	GDSC;CCLE	145.681	Down-regulation
Other_IKK_TBK1_ST	Q01094	E2F1	Q9UHD2	TBK1	T329	R323K	323	Missense	distal	-6	no	145.979	136.847	EPSD	GDSC	145.681	Loss
Other_IKK_TBK1_ST	Q01094	E2F1	Q9UHD2	TBK1	T329	A324T	324	Missense	distal	-5	no	145.979	145.971	EPSD	GDSC	145.681	Down-regulation
Other_IKK_TBK1_ST	Q01094	E2F1	Q9UHD2	TBK1	T344	L351V	351	Missense	distal	7	no	154.924	154.981	EPSD	GDSC;CCLE	145.681	Up-regulation
Other_IKK_TBK1_ST	Q01094	E2F1	Q9UHD2	TBK1	T344	S349Y	349	Missense	distal	5	no	154.924	151.736	EPSD	GDSC;CCLE	145.681	Down-regulation
Other_IKK_TBK1_ST	Q01094	E2F1	Q9UHD2	TBK1	S347	L351V	351	Missense	distal	4	no	145.460	150.815	EPSD	GDSC;CCLE	145.681	Gain
Other_IKK_TBK1_ST	Q01094	E2F1	Q9UHD2	TBK1	S349	L351V	351	Missense	proximal	2	no	145.505	148.034	EPSD	GDSC;CCLE	145.681	Gain
Other_IKK_TBK1_ST	P31749	AKT1	Q9UHD2	TBK1	T308	K307N	307	Missense	proximal	-1	no	166.338	166.441	EPSD;PhosphoSitePlus	GDSC;CCLE	145.681	Up-regulation
Other_IKK_TBK1_ST	P31749	AKT1	Q9UHD2	TBK1	S473	G478S	478	Missense	distal	5	no	176.752	180.355	PhosphoSitePlus;EPSD	GDSC;CCLE	145.681	Up-regulation
Other_IKK_TBK1_ST	P31749	AKT1	Q9UHD2	TBK1	S475	G478S	478	Missense	distal	3	no	156.921	155.327	EPSD	GDSC;CCLE	145.681	Down-regulation
Other_IKK_TBK1_ST	P31749	AKT1	Q9UHD2	TBK1	S477	G478S	478	Missense	proximal	1	no	145.361	146.690	EPSD	GDSC;CCLE	145.681	Gain
Other_IKK_TBK1_ST	Q9UHD2	TBK1	Q9UHD2	TBK1	T176	P182L	182	Missense	distal	6	no	158.077	160.545	EPSD	GDSC;CCLE	145.681	Up-regulation
Other_IKK_TBK1_ST	Q9UHD2	TBK1	Q9UHD2	TBK1	T333	H336Y	336	Missense	distal	3	no	161.014	161.443	EPSD	GDSC;CCLE	145.681	Up-regulation
Other_IKK_TBK1_ST	Q9UHD2	TBK1	Q9UHD2	TBK1	S509	L508I	508	Missense	proximal	-1	no	158.064	158.665	EPSD	GDSC	145.681	Up-regulation
Other_IKK_TBK1_ST	Q9UHD2	TBK1	Q9UHD2	TBK1	S510	L508I	508	Missense	proximal	-2	no	161.396	160.520	EPSD	GDSC	145.681	Down-regulation
Other_IKK_TBK1_ST	Q8IUC6	TICAM1	Q9UHD2	TBK1	T341	T342P	342	Missense	proximal	1	no	112.124	152.349	EPSD	GDSC;CCLE	145.681	Gain
Other_IKK_TBK1_ST	Q8IUC6	TICAM1	Q9UHD2	TBK1	S343	D340Y	340	Missense	distal	-3	no	146.451	145.422	EPSD	GDSC;CCLE	145.681	Loss
Other_IKK_TBK1_ST	Q8IUC6	TICAM1	Q9UHD2	TBK1	S343	T342P	342	Missense	proximal	-1	no	146.451	146.668	EPSD	GDSC;CCLE	145.681	Up-regulation
Other_IKK_TBK1_ST	Q8IUC6	TICAM1	Q9UHD2	TBK1	S343	T346I	346	Missense	distal	3	no	146.451	145.817	EPSD	GDSC;CCLE	145.681	Down-regulation
Other_IKK_TBK1_ST	Q04206	RELA	Q9UHD2	TBK1	S261	D259G	259	Missense	proximal	-2	no	152.743	151.324	EPSD	GDSC;CCLE	145.681	Down-regulation
Other_IKK_TBK1_ST	Q04206	RELA	Q9UHD2	TBK1	S261	A258T	258	Missense	distal	-3	no	152.743	153.534	EPSD	GDSC;CCLE	145.681	Up-regulation
Other_IKK_TBK1_ST	Q7Z434	MAVS	Q9UHD2	TBK1	T388	T393I	393	Missense	distal	5	no	147.669	146.282	EPSD	GDSC;CCLE	145.681	Down-regulation
Other_IKK_TBK1_ST	P30086	PEBP1	Q9UHD2	TBK1	S52	L58H	58	Missense	distal	6	no	146.491	143.620	EPSD	GDSC	145.681	Loss
Other_IKK_TBK1_ST	P30086	PEBP1	Q9UHD2	TBK1	S52	P50A	50	Missense	proximal	-2	no	146.491	146.579	EPSD	GDSC;CCLE	145.681	Up-regulation
Other_IKK_TBK1_ST	P30086	PEBP1	Q9UHD2	TBK1	S60	L58H	58	Missense	proximal	-2	no	153.647	152.683	EPSD	GDSC	145.681	Down-regulation
Other_IKK_TBK1_ST	P03372	ESR1	Q9UHD2	TBK1	S305	K299N	299	Missense	distal	-6	no	183.655	188.890	PhosphoSitePlus	GDSC;CCLE	145.681	Up-regulation
Other_IKK_TBK1_ST	P03372	ESR1	Q9UHD2	TBK1	S305	I298V	298	Missense	distal	-7	no	183.655	184.414	PhosphoSitePlus	GDSC	145.681	Up-regulation
TK_Tie_TEK_Y	Q02763	TEK	Q02763	TEK	Y1102	T1105I	1105	Missense	distal	3	no	2.672	2.676	EPSD	GDSC	0.993	Up-regulation
TK_Tie_TEK_Y	Q02763	TEK	Q02763	TEK	Y1102	N1104D	1104	Missense	proximal	2	no	2.672	2.092	EPSD	GDSC	0.993	Down-regulation
TK_Tie_TEK_Y	Q02763	TEK	Q02763	TEK	Y1108	T1105I	1105	Missense	distal	-3	no	2.631	2.618	EPSD;PhosphoSitePlus	GDSC	0.993	Down-regulation
TK_Tie_TEK_Y	Q02763	TEK	Q02763	TEK	Y1108	N1104D	1104	Missense	distal	-4	no	2.631	2.591	EPSD;PhosphoSitePlus	GDSC	0.993	Down-regulation
CAMK_PKD_PRKD3_ST	Q9UQL6	HDAC5	O94806	PRKD3	S7	S7L	7	Missense	central	0	yes	2.665	0.000	EPSD	GDSC	1.136	Loss
CAMK_PKD_PRKD3_ST	Q9UQL6	HDAC5	O94806	PRKD3	S1108	E1114Q	1114	Missense	distal	6	no	1.221	1.217	EPSD	GDSC	1.136	Down-regulation
CAMK_PKD_PRKD3_ST	Q9Y2X7	GIT1	O94806	PRKD3	S25	S25Y	25	Missense	central	0	yes	1.575	0.000	EPSD	GDSC	1.136	Loss
AGC_PKC_PKCa_PRKCB_ST	P10636	MAPT	P05771-2	PRKCB	S171	D177V	177	Missense	distal	6	no	2.924	2.417	EPSD	GDSC	0.942	Down-regulation
AGC_PKC_PKCa_PRKCB_ST	P10636	MAPT	P05771-2	PRKCB	S214	V218G	218	Missense	distal	4	no	1.656	1.236	EPSD	GDSC	0.942	Down-regulation
AGC_PKC_PKCa_PRKCB_ST	P10636	MAPT	P05771-2	PRKCB	S355	E353D	353	Missense	proximal	-2	no	3.476	2.563	EPSD	GDSC;CCLE	0.942	Down-regulation
AGC_PKC_PKCa_PRKCB_ST	P10636	MAPT	P05771-2	PRKCB	T470	A475V	475	Missense	distal	5	no	3.997	3.862	EPSD	GDSC;CCLE	0.942	Down-regulation
AGC_PKC_PKCa_PRKCB_ST	P10636	MAPT	P05771-2	PRKCB	S633	V635I	635	Missense	proximal	2	no	1.139	1.159	EPSD	GDSC	0.942	Up-regulation
AGC_PKC_PKCa_PRKCB_ST	P10636	MAPT	P05771-2	PRKCB	S637	V635I	635	Missense	proximal	-2	no	4.072	4.102	EPSD	GDSC	0.942	Up-regulation
AGC_PKC_PKCa_PRKCB_ST	P05107	ITGB2	P05771-2	PRKCB	S496	K499N	499	Missense	distal	3	no	3.467	3.321	EPSD	GDSC;CCLE	0.942	Down-regulation
AGC_PKC_PKCa_PRKCB_ST	Q8NER1	TRPV1	P05771-2	PRKCB	S194	N192D	192	Missense	proximal	-2	no	1.478	0.953	EPSD	GDSC;CCLE	0.942	Down-regulation
AGC_PKC_PKCa_PRKCB_ST	Q8NER1	TRPV1	P05771-2	PRKCB	S194	A193S	193	Missense	proximal	-1	no	1.478	1.449	EPSD	GDSC;CCLE	0.942	Down-regulation
AGC_PKC_PKCa_PRKCB_ST	Q8NER1	TRPV1	P05771-2	PRKCB	S502	V508M	508	Missense	distal	6	no	4.026	4.342	EPSD	GDSC	0.942	Up-regulation
AGC_PKC_PKCa_PRKCB_ST	Q8NER1	TRPV1	P05771-2	PRKCB	S801	E799D	799	Missense	proximal	-2	no	7.183	6.270	EPSD	GDSC;CCLE	0.942	Down-regulation
AGC_PKC_PKCa_PRKCB_ST	Q8NER1	TRPV1	P05771-2	PRKCB	S801	R803*	803	Missense	proximal	2	no	7.183	-2.962	EPSD	GDSC	0.942	Loss
AGC_PKC_PKCa_PRKCB_ST	P98082	DAB2	P05771-2	PRKCB	S24	K28R	28	Missense	distal	4	no	12.413	12.527	PhosphoSitePlus	GDSC;CCLE	0.942	Up-regulation
AGC_PKC_PKCa_PRKCB_ST	P98082	DAB2	P05771-2	PRKCB	S249	S249Y	249	Missense	central	0	yes	4.764	0.000	EPSD	GDSC;CCLE	0.942	Loss
AGC_PKC_PKCa_PRKCB_ST	P98082	DAB2	P05771-2	PRKCB	S390	V391A	391	Missense	proximal	1	no	3.515	3.139	EPSD	GDSC;CCLE	0.942	Down-regulation
AGC_PKC_PKCa_PRKCB_ST	P98082	DAB2	P05771-2	PRKCB	S436	R441K	441	Missense	distal	5	no	1.854	1.915	EPSD	GDSC;CCLE	0.942	Up-regulation
AGC_PKC_PKCa_PRKCB_ST	P98082	DAB2	P05771-2	PRKCB	S436	I430V	430	Missense	distal	-6	no	1.854	1.890	EPSD	GDSC	0.942	Up-regulation
AGC_PKC_PKCa_PRKCB_ST	P98082	DAB2	P05771-2	PRKCB	S723	P719H	719	Missense	distal	-4	no	1.537	1.422	EPSD	GDSC	0.942	Down-regulation
AGC_PKC_PKCa_PRKCB_ST	P05771	PRKCB	P05771-2	PRKCB	S16	S16N	16	Missense	central	0	yes	2.322	0.000	EPSD	GDSC;CCLE	0.942	Loss
AGC_PKC_PKCa_PRKCB_ST	P05771	PRKCB	P05771-2	PRKCB	T17	S16N	16	Missense	proximal	-1	no	3.564	3.708	EPSD	GDSC;CCLE	0.942	Up-regulation
AGC_PKC_PKCa_PRKCB_ST	P05771	PRKCB	P05771-2	PRKCB	T48	C50*	50	Missense	proximal	2	no	2.065	-3.587	EPSD	GDSC	0.942	Loss
AGC_PKC_PKCa_PRKCB_ST	P05771	PRKCB	P05771-2	PRKCB	S241	E243K	243	Missense	proximal	2	no	-3.272	2.142	EPSD	GDSC;CCLE	0.942	Gain
AGC_PKC_PKCa_PRKCB_ST	P05771	PRKCB	P05771-2	PRKCB	T314	V316A	316	Missense	proximal	2	no	1.587	-1.110	EPSD	GDSC;CCLE	0.942	Loss
AGC_PKC_PKCa_PRKCB_ST	P05771	PRKCB	P05771-2	PRKCB	T314	E319K	319	Missense	distal	5	no	1.587	1.757	EPSD	GDSC;CCLE	0.942	Up-regulation
AGC_PKC_PKCa_PRKCB_ST	P53004	BLVRA	P05771-2	PRKCB	S21	R18G	18	Missense	distal	-3	no	6.698	2.483	EPSD	GDSC	0.942	Down-regulation
AGC_PKC_PKCa_PRKCB_ST	Q07869	PPARA	P05771-2	PRKCB	S230	I228V	228	Missense	proximal	-2	no	2.949	2.918	PhosphoSitePlus;EPSD	GDSC;CCLE	0.942	Down-regulation
AGC_PKC_PKCa_PRKCB_ST	P15336	ATF2	P05771-2	PRKCB	S340	R342H	342	Missense	proximal	2	no	2.871	-3.490	EPSD	GDSC;CCLE	0.942	Loss
AGC_PKC_PKCa_PRKCB_ST	P43629	KIR3DL1	P05771-2	PRKCB	S245	R247Q	247	Missense	proximal	2	no	3.334	-3.215	EPSD	GDSC	0.942	Loss
AGC_PKC_PKCa_PRKCB_ST	P43629	KIR3DL1	P05771-2	PRKCB	S245	R247W	247	Missense	proximal	2	no	3.334	-6.179	EPSD	GDSC;CCLE	0.942	Loss
AGC_PKC_PKCa_PRKCB_ST	P43629	KIR3DL1	P05771-2	PRKCB	S245	V240A	240	Missense	distal	-5	no	3.334	3.363	EPSD	GDSC;CCLE	0.942	Up-regulation
AGC_PKC_PKCa_PRKCB_ST	P43629	KIR3DL1	P05771-2	PRKCB	S245	E238D	238	Missense	distal	-7	no	3.334	3.257	EPSD	GDSC	0.942	Down-regulation
AGC_PKC_PKCa_PRKCB_ST	P43629	KIR3DL1	P05771-2	PRKCB	S245	S239I	239	Missense	distal	-6	no	3.334	3.288	EPSD	GDSC;CCLE	0.942	Down-regulation
AGC_PKC_PKCa_PRKCB_ST	P43629	KIR3DL1	P05771-2	PRKCB	S296	G289R	289	Missense	distal	-7	no	2.010	1.659	EPSD	GDSC	0.942	Down-regulation
AGC_PKC_PKCa_PRKCB_ST	P43629	KIR3DL1	P05771-2	PRKCB	S296	G295S	295	Missense	proximal	-1	no	2.010	1.939	EPSD	GDSC	0.942	Down-regulation
AGC_PKC_PKCa_PRKCB_ST	P43629	KIR3DL1	P05771-2	PRKCB	S415	P422S	422	Missense	distal	7	no	7.824	7.731	PhosphoSitePlus	GDSC;CCLE	0.942	Down-regulation
AGC_PKC_PKCa_PRKCB_ST	P56537	EIF6	P05771-2	PRKCB	S6	E8Q	8	Missense	proximal	2	no	1.585	2.073	EPSD	GDSC	0.942	Up-regulation
AGC_PKC_PKCa_PRKCB_ST	P56537	EIF6	P05771-2	PRKCB	S6	A5S	5	Missense	proximal	-1	no	1.585	1.556	EPSD	GDSC	0.942	Down-regulation
AGC_PKC_PKCa_PRKCB_ST	P56537	EIF6	P05771-2	PRKCB	S235	R237Q	237	Missense	proximal	2	no	2.749	-3.800	PhosphoSitePlus	GDSC;CCLE	0.942	Loss
AGC_PKC_PKCa_PRKCB_ST	P56537	EIF6	P05771-2	PRKCB	S239	R237Q	237	Missense	proximal	-2	no	1.491	0.519	EPSD	GDSC;CCLE	0.942	Loss
AGC_PKC_PKCa_PRKCB_ST	Q06124	PTPN11	P05771-2	PRKCB	S580	V583M	583	Missense	distal	3	no	9.230	9.554	EPSD	GDSC;CCLE	0.942	Up-regulation
AGC_PKC_PKCa_PRKCB_ST	P49841	GSK3B	P05771-2	PRKCB	S2	T8P	8	Missense	distal	6	no	3.927	4.142	EPSD	GDSC	0.942	Up-regulation
AGC_PKC_PKCa_PRKCB_ST	P49841	GSK3B	P05771-2	PRKCB	S9	T8P	8	Missense	proximal	-1	no	2.332	2.090	PhosphoSitePlus	GDSC	0.942	Down-regulation
AGC_PKC_PKCa_PRKCB_ST	P49841	GSK3B	P05771-2	PRKCB	S13	T8P	8	Missense	distal	-5	no	1.665	1.589	EPSD	GDSC	0.942	Down-regulation
AGC_PKC_PKCa_PRKCB_ST	P35579	MYH9	P05771-2	PRKCB	S541	T538I	538	Missense	distal	-3	no	1.313	0.599	EPSD	GDSC;CCLE	0.942	Loss
AGC_PKC_PKCa_PRKCB_ST	P35579	MYH9	P05771-2	PRKCB	S1122	Q1117*	1117	Missense	distal	-5	no	1.709	1.386	EPSD	GDSC	0.942	Down-regulation
AGC_PKC_PKCa_PRKCB_ST	P35579	MYH9	P05771-2	PRKCB	S1122	R1124H	1124	Missense	proximal	2	no	1.709	-4.653	EPSD	GDSC;CCLE	0.942	Loss
AGC_PKC_PKCa_PRKCB_ST	P35579	MYH9	P05771-2	PRKCB	T1208	A1213G	1213	Missense	distal	5	no	2.263	2.112	EPSD	GDSC;CCLE	0.942	Down-regulation
AGC_PKC_PKCa_PRKCB_ST	P35579	MYH9	P05771-2	PRKCB	S1243	R1247H	1247	Missense	distal	4	no	2.520	1.698	EPSD	GDSC;CCLE	0.942	Down-regulation
AGC_PKC_PKCa_PRKCB_ST	P35579	MYH9	P05771-2	PRKCB	S1340	E1346*	1346	Missense	distal	6	no	6.141	4.568	EPSD	GDSC	0.942	Down-regulation
AGC_PKC_PKCa_PRKCB_ST	P35579	MYH9	P05771-2	PRKCB	S1398	L1397P	1397	Missense	proximal	-1	no	4.442	4.391	EPSD	GDSC;CCLE	0.942	Down-regulation
AGC_PKC_PKCa_PRKCB_ST	P35579	MYH9	P05771-2	PRKCB	S1398	L1394P	1394	Missense	distal	-4	no	4.442	4.480	EPSD	GDSC;CCLE	0.942	Up-regulation
AGC_PKC_PKCa_PRKCB_ST	P35579	MYH9	P05771-2	PRKCB	S1480	L1479M	1479	Missense	proximal	-1	no	0.806	1.007	EPSD	GDSC;CCLE	0.942	Gain
AGC_PKC_PKCa_PRKCB_ST	P35579	MYH9	P05771-2	PRKCB	S1808	Y1805*	1805	Missense	distal	-3	no	1.603	-0.253	EPSD	GDSC	0.942	Loss
AGC_PKC_PKCa_PRKCB_ST	Q9UBS0	RPS6KB2	P05771-2	PRKCB	T228	G231S	231	Missense	distal	3	no	1.590	1.853	EPSD	GDSC;CCLE	0.942	Up-regulation
AGC_PKC_PKCa_PRKCB_ST	Q9UBS0	RPS6KB2	P05771-2	PRKCB	S417	R419Q	419	Missense	proximal	2	no	1.767	-4.781	EPSD	GDSC;CCLE	0.942	Loss
AGC_PKC_PKCa_PRKCB_ST	Q9UBS0	RPS6KB2	P05771-2	PRKCB	S468	R465C	465	Missense	distal	-3	no	3.257	-0.643	EPSD	GDSC;CCLE	0.942	Loss
AGC_PKC_PKCa_PRKCB_ST	Q9UBS0	RPS6KB2	P05771-2	PRKCB	T470	R465C	465	Missense	distal	-5	no	1.712	1.479	EPSD	GDSC;CCLE	0.942	Down-regulation
AGC_PKC_PKCa_PRKCB_ST	Q9H1D0	TRPV6	P05771-2	PRKCB	S182	A187T	187	Missense	distal	5	no	3.656	3.594	EPSD	GDSC;CCLE	0.942	Down-regulation
AGC_PKC_PKCa_PRKCB_ST	Q9H1D0	TRPV6	P05771-2	PRKCB	S184	A187T	187	Missense	distal	3	no	3.920	4.314	PhosphoSitePlus;EPSD	GDSC;CCLE	0.942	Up-regulation
AGC_PKC_PKCa_PRKCB_ST	P21730	C5AR1	P05771-2	PRKCB	S332	T339A	339	Missense	distal	7	no	1.111	1.201	EPSD	GDSC;CCLE	0.942	Up-regulation
AGC_PKC_PKCa_PRKCB_ST	P21730	C5AR1	P05771-2	PRKCB	S332	R337H	337	Missense	distal	5	no	1.111	0.734	EPSD	GDSC;CCLE	0.942	Loss
AGC_PKC_PKCa_PRKCB_ST	P21730	C5AR1	P05771-2	PRKCB	S334	T339A	339	Missense	distal	5	no	0.990	1.052	PhosphoSitePlus	GDSC;CCLE	0.942	Up-regulation
AGC_PKC_PKCa_PRKCB_ST	P21730	C5AR1	P05771-2	PRKCB	S334	R337H	337	Missense	distal	3	no	0.990	0.185	PhosphoSitePlus	GDSC;CCLE	0.942	Loss
AGC_PKC_PKCa_PRKCB_ST	P14598	NCF1	P05771-2	PRKCB	T93	Q91K	91	Missense	proximal	-2	no	0.072	1.154	EPSD	GDSC;CCLE	0.942	Gain
AGC_PKC_PKCa_PRKCB_ST	P14598	NCF1	P05771-2	PRKCB	S320	Y324H	324	Missense	distal	4	no	1.012	0.793	PhosphoSitePlus;EPSD	GDSC;CCLE	0.942	Loss
AGC_PKC_PKCa_PRKCB_ST	P14598	NCF1	P05771-2	PRKCB	S328	Y324H	324	Missense	distal	-4	no	6.012	6.122	EPSD;PhosphoSitePlus	GDSC;CCLE	0.942	Up-regulation
AGC_PKC_PKCa_PRKCB_ST	Q14152	EIF3A	P05771-2	PRKCB	S978	D984E	984	Missense	distal	6	no	3.884	4.284	EPSD	GDSC	0.942	Up-regulation
AGC_PKC_PKCa_PRKCB_ST	Q14152	EIF3A	P05771-2	PRKCB	S988	D984E	984	Missense	distal	-4	no	3.944	3.838	EPSD	GDSC	0.942	Down-regulation
AGC_PKC_PKCa_PRKCB_ST	Q14152	EIF3A	P05771-2	PRKCB	S1028	L1022M	1022	Missense	distal	-6	no	3.070	3.128	EPSD	GDSC	0.942	Up-regulation
AGC_PKC_PKCa_PRKCB_ST	Q14152	EIF3A	P05771-2	PRKCB	S1262	D1266N	1266	Missense	distal	4	no	2.811	3.064	EPSD	GDSC	0.942	Up-regulation
AGC_PKC_PKCa_PRKCB_ST	Q14152	EIF3A	P05771-2	PRKCB	S1262	S1262A	1262	Missense	central	0	yes	2.811	0.000	EPSD	GDSC	0.942	Loss
AGC_PKC_PKCa_PRKCB_ST	Q14152	EIF3A	P05771-2	PRKCB	S1262	S1256F	1256	Missense	distal	-6	no	2.811	2.706	EPSD	GDSC;CCLE	0.942	Down-regulation
AGC_PKC_PKCa_PRKCB_ST	Q14152	EIF3A	P05771-2	PRKCB	S1263	D1266N	1266	Missense	distal	3	no	6.275	6.330	EPSD	GDSC	0.942	Up-regulation
AGC_PKC_PKCa_PRKCB_ST	Q14152	EIF3A	P05771-2	PRKCB	S1263	S1262A	1262	Missense	proximal	-1	no	6.275	6.303	EPSD	GDSC	0.942	Up-regulation
AGC_PKC_PKCa_PRKCB_ST	Q14152	EIF3A	P05771-2	PRKCB	S1263	R1270K	1270	Missense	distal	7	no	6.275	6.385	EPSD	GDSC;CCLE	0.942	Up-regulation
AGC_PKC_PKCa_PRKCB_ST	Q14152	EIF3A	P05771-2	PRKCB	S1263	S1256F	1256	Missense	distal	-7	no	6.275	6.347	EPSD	GDSC;CCLE	0.942	Up-regulation
AGC_PKC_PKCa_PRKCB_ST	P20700	LMNB1	P05771-2	PRKCB	T219	R226C	226	Missense	distal	7	no	4.447	4.644	EPSD	GDSC	0.942	Up-regulation
AGC_PKC_PKCa_PRKCB_ST	P20700	LMNB1	P05771-2	PRKCB	S232	R226C	226	Missense	distal	-6	no	4.265	3.910	EPSD	GDSC	0.942	Down-regulation
AGC_PKC_PKCa_PRKCB_ST	P20700	LMNB1	P05771-2	PRKCB	T411	R416Q	416	Missense	distal	5	no	2.783	2.806	EPSD	GDSC;CCLE	0.942	Up-regulation
AGC_PKC_PKCa_PRKCB_ST	P20700	LMNB1	P05771-2	PRKCB	T411	K417T	417	Missense	distal	6	no	2.783	1.861	EPSD	GDSC;CCLE	0.942	Down-regulation
AGC_PKC_PKCa_PRKCB_ST	Q04637	EIF4G1	P05771-2	PRKCB	T179	R183*	183	Missense	distal	4	no	2.988	1.797	EPSD	GDSC	0.942	Down-regulation
AGC_PKC_PKCa_PRKCB_ST	Q04637	EIF4G1	P05771-2	PRKCB	T179	K174R	174	Missense	distal	-5	no	2.988	3.026	EPSD	GDSC	0.942	Up-regulation
AGC_PKC_PKCa_PRKCB_ST	Q04637	EIF4G1	P05771-2	PRKCB	T179	T179P	179	Missense	central	0	yes	2.988	0.000	EPSD	GDSC;CCLE	0.942	Loss
AGC_PKC_PKCa_PRKCB_ST	Q04637	EIF4G1	P05771-2	PRKCB	S1041	G1043R	1043	Missense	proximal	2	no	-5.069	3.665	EPSD	GDSC;CCLE	0.942	Gain
AGC_PKC_PKCa_PRKCB_ST	Q04637	EIF4G1	P05771-2	PRKCB	S1077	K1074T	1074	Missense	distal	-3	no	2.648	-0.064	EPSD	GDSC	0.942	Loss
AGC_PKC_PKCa_PRKCB_ST	Q04637	EIF4G1	P05771-2	PRKCB	T1182	D1175V	1175	Missense	distal	-7	no	2.924	3.119	EPSD	GDSC;CCLE	0.942	Up-regulation
AGC_PKC_PKCa_PRKCB_ST	P62491	RAB11A	P05771-2	PRKCB	S177	K179*	179	Missense	proximal	2	no	5.356	-3.165	PhosphoSitePlus	GDSC	0.942	Loss
AGC_PKC_PKCa_PRKCB_ST	P62491	RAB11A	P05771-2	PRKCB	S177	V176A	176	Missense	proximal	-1	no	5.356	5.252	PhosphoSitePlus	GDSC;CCLE	0.942	Down-regulation
AGC_PKC_PKCa_PRKCB_ST	O15350	TP73	P05771-2	PRKCB	S388	Y389C	389	Missense	proximal	1	no	2.009	0.184	PhosphoSitePlus	GDSC;CCLE	0.942	Loss
AGC_PKC_PKCa_PRKCB_ST	P28329	CHAT	P05771-2	PRKCB	S244	D250G	250	Missense	distal	6	no	1.015	0.334	EPSD	GDSC;CCLE	0.942	Loss
AGC_PKC_PKCa_PRKCB_ST	P28329	CHAT	P05771-2	PRKCB	S377	E382K	382	Missense	distal	5	no	1.429	1.599	EPSD	GDSC;CCLE	0.942	Up-regulation
AGC_PKC_PKCa_PRKCB_ST	P28329	CHAT	P05771-2	PRKCB	T462	S465R	465	Missense	distal	3	no	1.163	1.928	EPSD	GDSC;CCLE	0.942	Up-regulation
AGC_PKC_PKCa_PRKCB_ST	P28329	CHAT	P05771-2	PRKCB	S464	S465R	465	Missense	proximal	1	no	5.753	7.777	EPSD	GDSC;CCLE	0.942	Up-regulation
AGC_PKC_PKCa_PRKCB_ST	P28329	CHAT	P05771-2	PRKCB	S465	S465R	465	Missense	central	0	yes	4.475	0.000	EPSD	GDSC;CCLE	0.942	Loss
AGC_PKC_PKCa_PRKCB_ST	P28329	CHAT	P05771-2	PRKCB	S558	E555D	555	Missense	distal	-3	no	6.129	5.334	EPSD	GDSC;CCLE	0.942	Down-regulation
AGC_PKC_PKCa_PRKCB_ST	P28329	CHAT	P05771-2	PRKCB	S594	A590D	590	Missense	distal	-4	no	2.132	2.067	EPSD	GDSC;CCLE	0.942	Down-regulation
AGC_PKC_PKCa_PRKCB_ST	P35637	FUS	P05771-2	PRKCB	T326	D327H	327	Missense	proximal	1	no	2.138	2.135	EPSD	GDSC;CCLE	0.942	Down-regulation
AGC_PKC_PKCa_PRKCB_ST	P35637	FUS	P05771-2	PRKCB	S360	S360F	360	Missense	central	0	yes	1.325	0.000	EPSD	GDSC;CCLE	0.942	Loss
AGC_PKC_PKCa_PRKCB_ST	Q9UBU3	GHRL	P05771-2	PRKCB	S41	K42N	42	Missense	proximal	1	no	9.523	6.704	PhosphoSitePlus	GDSC;CCLE	0.942	Down-regulation
AGC_PKC_PKCa_PRKCB_ST	P49840	GSK3A	P05771-2	PRKCB	S266	R272*	272	Missense	distal	6	no	2.948	1.029	EPSD	GDSC	0.942	Down-regulation
TK_Syk_SYK_Y	P02730	SLC4A1	P43405	SYK	Y21	E19D	19	Missense	proximal	-2	no	26.467	27.273	EPSD;PhosphoSitePlus	GDSC;CCLE	13.041	Up-regulation
TK_Syk_SYK_Y	P02730	SLC4A1	P43405	SYK	Y359	G366V	366	Missense	distal	7	no	17.193	17.058	EPSD;PhosphoSitePlus	GDSC;CCLE	13.041	Down-regulation
TK_Syk_SYK_Y	P29353	SHC1	P43405	SYK	Y349	Y349H	349	Missense	central	0	yes	15.004	0.000	EPSD	GDSC;CCLE	13.041	Loss
TK_Syk_SYK_Y	P29353	SHC1	P43405	SYK	Y350	Y349H	349	Missense	proximal	-1	no	15.904	16.855	EPSD	GDSC;CCLE	13.041	Up-regulation
TK_Syk_SYK_Y	Q8IWV1	LAX1	P43405	SYK	Y268	Q263R	263	Missense	distal	-5	no	21.314	21.267	PhosphoSitePlus;EPSD	GDSC;CCLE	13.041	Down-regulation
TK_Syk_SYK_Y	Q8IWV1	LAX1	P43405	SYK	Y373	E374D	374	Missense	proximal	1	no	29.132	25.492	EPSD;PhosphoSitePlus	GDSC;CCLE	13.041	Down-regulation
TK_Syk_SYK_Y	P19174	PLCG1	P43405	SYK	Y783	E785K	785	Missense	proximal	2	no	15.446	13.389	EPSD;PhosphoSitePlus	GDSC;CCLE	13.041	Down-regulation
TK_Syk_SYK_Y	Q8WV28	BLNK	P43405	SYK	Y84	M83I	83	Missense	proximal	-1	no	22.896	22.913	EPSD;PhosphoSitePlus	GDSC;CCLE	13.041	Up-regulation
TK_Syk_SYK_Y	Q8WV28	BLNK	P43405	SYK	Y96	P100L	100	Missense	distal	4	no	27.373	26.395	PhosphoSitePlus;EPSD	GDSC;CCLE	13.041	Down-regulation
TK_Syk_SYK_Y	Q8WV28	BLNK	P43405	SYK	Y119	I120T	120	Missense	proximal	1	no	14.514	14.098	EPSD	GDSC	13.041	Down-regulation
TK_Syk_SYK_Y	Q8WV28	BLNK	P43405	SYK	Y178	V182M	182	Missense	distal	4	no	20.252	20.531	EPSD;PhosphoSitePlus	GDSC	13.041	Up-regulation
TK_Syk_SYK_Y	Q8WV28	BLNK	P43405	SYK	Y178	E175G	175	Missense	distal	-3	no	20.252	17.595	EPSD;PhosphoSitePlus	GDSC	13.041	Down-regulation
TK_Syk_SYK_Y	Q8WV28	BLNK	P43405	SYK	Y189	V182M	182	Missense	distal	-7	no	24.592	24.325	EPSD;PhosphoSitePlus	GDSC	13.041	Down-regulation
TK_Syk_SYK_Y	Q8WV28	BLNK	P43405	SYK	Y189	Y189H	189	Missense	central	0	yes	24.592	0.000	EPSD;PhosphoSitePlus	GDSC;CCLE	13.041	Loss
TK_Syk_SYK_Y	P16885	PLCG2	P43405	SYK	Y1048	P1050Q	1050	Missense	proximal	2	no	16.841	16.694	EPSD	GDSC;CCLE	13.041	Down-regulation
TK_Syk_SYK_Y	P14317	HCLS1	P43405	SYK	Y378	N376T	376	Missense	proximal	-2	no	30.061	29.238	PhosphoSitePlus;EPSD	GDSC	13.041	Down-regulation
TK_Syk_SYK_Y	P14317	HCLS1	P43405	SYK	Y378	N376H	376	Missense	proximal	-2	no	30.061	28.904	PhosphoSitePlus;EPSD	GDSC	13.041	Down-regulation
TK_Syk_SYK_Y	P14317	HCLS1	P43405	SYK	Y397	V400A	400	Missense	distal	3	no	29.543	30.321	EPSD;PhosphoSitePlus	GDSC;CCLE	13.041	Up-regulation
TK_Syk_SYK_Y	P12318	FCGR2A	P43405	SYK	Y281	L274F	274	Missense	distal	-7	no	23.005	22.427	EPSD;PhosphoSitePlus	GDSC	13.041	Down-regulation
TK_Syk_SYK_Y	P12318	FCGR2A	P43405	SYK	Y304	D300N	300	Missense	distal	-4	no	15.344	14.101	PhosphoSitePlus;EPSD	GDSC;CCLE	13.041	Down-regulation
TK_Syk_SYK_Y	P13569	CFTR	P43405	SYK	Y512	I507V	507	Missense	distal	-5	no	13.984	13.936	PhosphoSitePlus	GDSC;CCLE	13.041	Down-regulation
TK_Syk_SYK_Y	Q9GZY6	LAT2	P43405	SYK	Y40	R46H	46	Missense	distal	6	no	13.112	13.135	EPSD	GDSC	13.041	Up-regulation
TK_Syk_SYK_Y	Q9GZY6	LAT2	P43405	SYK	Y110	M116V	116	Missense	distal	6	no	20.418	20.377	EPSD	GDSC	13.041	Down-regulation
TK_Syk_SYK_Y	Q9GZY6	LAT2	P43405	SYK	Y110	I111V	111	Missense	proximal	1	no	20.418	21.641	EPSD	GDSC	13.041	Up-regulation
TK_Syk_SYK_Y	Q9GZY6	LAT2	P43405	SYK	Y233	V234M	234	Missense	proximal	1	no	21.413	19.595	PhosphoSitePlus;EPSD	GDSC;CCLE	13.041	Down-regulation
TK_Syk_SYK_Y	Q14247	CTTN	P43405	SYK	Y486	E490K	490	Missense	distal	4	no	16.556	16.151	EPSD	GDSC;CCLE	13.041	Down-regulation
TK_Syk_SYK_Y	P52566	ARHGDIB	P43405	SYK	Y24	E17D	17	Missense	distal	-7	no	17.657	17.234	PhosphoSitePlus	GDSC;CCLE	13.041	Down-regulation
TK_Syk_SYK_Y	P42229	STAT5A	P43405	SYK	Y694	P697L	697	Missense	distal	3	no	15.261	11.526	PhosphoSitePlus	GDSC	13.041	Loss
TK_Syk_SYK_Y	P22681	CBL	P43405	SYK	Y455	N454K	454	Missense	proximal	-1	no	16.274	13.972	EPSD	GDSC;CCLE	13.041	Down-regulation
TK_Syk_SYK_Y	P22681	CBL	P43405	SYK	Y700	Y700C	700	Missense	central	0	yes	20.796	0.000	PhosphoSitePlus;EPSD	GDSC;CCLE	13.041	Loss
TK_Syk_SYK_Y	P22681	CBL	P43405	SYK	Y731	Q738*	738	Missense	distal	7	no	19.225	18.676	EPSD;PhosphoSitePlus	GDSC	13.041	Down-regulation
TK_Syk_SYK_Y	P22681	CBL	P43405	SYK	Y774	D772E	772	Missense	proximal	-2	no	27.322	26.516	EPSD;PhosphoSitePlus	GDSC	13.041	Down-regulation
TK_Syk_SYK_Y	P37840	SNCA	P43405	SYK	Y125	M127I	127	Missense	proximal	2	no	26.604	26.190	EPSD;PhosphoSitePlus	GDSC	13.041	Down-regulation
TK_Syk_SYK_Y	P37840	SNCA	P43405	SYK	Y125	E130G	130	Missense	distal	5	no	26.604	26.819	EPSD;PhosphoSitePlus	GDSC	13.041	Up-regulation
TK_Syk_SYK_Y	P37840	SNCA	P43405	SYK	Y133	M127I	127	Missense	distal	-6	no	19.060	19.110	PhosphoSitePlus;EPSD	GDSC	13.041	Up-regulation
TK_Syk_SYK_Y	P37840	SNCA	P43405	SYK	Y133	E130G	130	Missense	distal	-3	no	19.060	16.403	PhosphoSitePlus;EPSD	GDSC	13.041	Down-regulation
TK_Syk_SYK_Y	P37840	SNCA	P43405	SYK	Y136	E130G	130	Missense	distal	-6	no	20.521	19.626	EPSD;PhosphoSitePlus	GDSC	13.041	Down-regulation
TK_Syk_SYK_Y	P43405	SYK	P43405	SYK	Y131	K133E	133	Missense	proximal	2	no	11.073	13.131	EPSD	GDSC;CCLE	13.041	Gain
TK_Syk_SYK_Y	P43405	SYK	P43405	SYK	Y348	P355L	355	Missense	distal	7	no	25.445	24.745	EPSD;PhosphoSitePlus	GDSC;CCLE	13.041	Down-regulation
TK_Syk_SYK_Y	P43405	SYK	P43405	SYK	Y352	P355L	355	Missense	distal	3	no	19.592	15.857	PhosphoSitePlus;EPSD	GDSC;CCLE	13.041	Down-regulation
TK_Syk_SYK_Y	P43405	SYK	P43405	SYK	Y525	R520S	520	Missense	distal	-5	no	17.499	18.127	EPSD;PhosphoSitePlus	GDSC	13.041	Up-regulation
TK_Syk_SYK_Y	P43405	SYK	P43405	SYK	Y526	R520S	520	Missense	distal	-6	no	17.966	18.488	EPSD;PhosphoSitePlus	GDSC	13.041	Up-regulation
TK_Syk_SYK_Y	Q06187	BTK	P43405	SYK	Y551	D549A	549	Missense	proximal	-2	no	15.858	11.504	PhosphoSitePlus	GDSC;CCLE	13.041	Loss
TK_Syk_SYK_Y	Q8N6F7	GCSAM	P43405	SYK	Y80	Y80D	80	Missense	central	0	yes	13.551	0.000	EPSD	GDSC	13.041	Loss
TK_Syk_SYK_Y	Q8N6F7	GCSAM	P43405	SYK	Y148	R142*	142	Missense	distal	-6	no	20.333	19.598	EPSD	GDSC	13.041	Down-regulation
TK_Syk_SYK_Y	Q8N6F7	GCSAM	P43405	SYK	Y148	A141T	141	Missense	distal	-7	no	20.333	20.701	EPSD	GDSC;CCLE	13.041	Up-regulation
TK_Syk_SYK_Y	Q13094	LCP2	P43405	SYK	Y113	S107Y	107	Missense	distal	-6	no	26.457	25.720	PhosphoSitePlus;EPSD	GDSC;CCLE	13.041	Down-regulation
TK_Syk_SYK_Y	Q13094	LCP2	P43405	SYK	Y128	G126E	126	Missense	proximal	-2	no	32.230	34.010	EPSD;PhosphoSitePlus	GDSC	13.041	Up-regulation
STE_STE20_FRAY_STK39_ST	Q13621	SLC12A1	Q9UEW8	STK39	S91	A88V	88	Missense	distal	-3	no	87.080	87.784	EPSD	GDSC;CCLE	61.825	Up-regulation
STE_STE20_FRAY_STK39_ST	Q13621	SLC12A1	Q9UEW8	STK39	T95	A88V	88	Missense	distal	-7	no	174.299	174.408	EPSD;PhosphoSitePlus	GDSC;CCLE	61.825	Up-regulation
STE_STE20_FRAY_STK39_ST	Q13621	SLC12A1	Q9UEW8	STK39	S120	P124S	124	Missense	distal	4	no	64.347	63.330	EPSD	GDSC;CCLE	61.825	Down-regulation
STE_STE20_FRAY_STK39_ST	Q9Y6R1	SLC4A4	Q9UEW8	STK39	S38	R40M	40	Missense	proximal	2	no	82.066	90.897	EPSD	GDSC;CCLE	61.825	Up-regulation
STE_STE20_FRAY_STK39_ST	Q9Y6R1	SLC4A4	Q9UEW8	STK39	T49	E53*	53	Missense	distal	4	no	94.930	95.473	EPSD	GDSC	61.825	Up-regulation
STE_STE20_FRAY_STK39_ST	Q9Y6R1	SLC4A4	Q9UEW8	STK39	T207	L200V	200	Missense	distal	-7	no	82.087	80.769	EPSD	GDSC;CCLE	61.825	Down-regulation
STE_STE20_FRAY_STK39_ST	P55011	SLC12A2	Q9UEW8	STK39	T986	G982D	982	Missense	distal	-4	no	101.283	109.987	EPSD	GDSC;CCLE	61.825	Up-regulation
STE_STE20_FRAY_STK39_ST	Q9H2X9	SLC12A5	Q9UEW8	STK39	S54	K61N	61	Missense	distal	7	no	63.461	63.447	EPSD	GDSC;CCLE	61.825	Down-regulation
STE_STE20_FRAY_STK39_ST	Q9H2X9	SLC12A5	Q9UEW8	STK39	S54	I52M	52	Missense	proximal	-2	no	63.461	67.154	EPSD	GDSC;CCLE	61.825	Up-regulation
STE_STE20_FRAY_STK39_ST	Q9H2X9	SLC12A5	Q9UEW8	STK39	S54	P50L	50	Missense	distal	-4	no	63.461	42.095	EPSD	GDSC;CCLE	61.825	Loss
STE_STE20_FRAY_STK39_ST	Q9Y666	SLC12A7	Q9UEW8	STK39	T958	A963V	963	Missense	distal	5	no	81.330	85.264	EPSD	GDSC;CCLE	61.825	Up-regulation
STE_STE20_FRAY_STK39_ST	Q9Y666	SLC12A7	Q9UEW8	STK39	S960	A963V	963	Missense	distal	3	no	72.283	71.585	EPSD	GDSC;CCLE	61.825	Down-regulation
STE_STE20_FRAY_STK39_ST	Q9Y666	SLC12A7	Q9UEW8	STK39	T962	A963V	963	Missense	proximal	1	no	71.316	88.108	EPSD	GDSC;CCLE	61.825	Up-regulation
STE_STE20_FRAY_STK39_ST	Q9UHW9	SLC12A6	Q9UEW8	STK39	S96	G99R	99	Missense	distal	3	no	125.264	126.822	EPSD;PhosphoSitePlus	GDSC;CCLE	61.825	Up-regulation
STE_STE20_FRAY_STK39_ST	Q9UP95	SLC12A4	Q9UEW8	STK39	T5	H3R	3	Missense	proximal	-2	no	86.231	83.002	EPSD;PhosphoSitePlus	GDSC;CCLE	61.825	Down-regulation
STE_STE20_FRAY_STK39_ST	Q9UP95	SLC12A4	Q9UEW8	STK39	T1021	R1017Q	1017	Missense	distal	-4	no	60.673	63.217	EPSD	GDSC;CCLE	61.825	Gain
STE_STE20_FRAY_STK39_ST	P55017	SLC12A3	Q9UEW8	STK39	T14	D12Y	12	Missense	proximal	-2	no	75.566	76.343	EPSD	GDSC	61.825	Up-regulation
STE_STE20_FRAY_STK39_ST	P55017	SLC12A3	Q9UEW8	STK39	T14	A13P	13	Missense	proximal	-1	no	75.566	78.409	EPSD	GDSC	61.825	Up-regulation
STE_STE20_FRAY_STK39_ST	P55017	SLC12A3	Q9UEW8	STK39	T55	T60M	60	Missense	distal	5	no	164.354	158.184	EPSD;PhosphoSitePlus	GDSC	61.825	Down-regulation
STE_STE20_FRAY_STK39_ST	P55017	SLC12A3	Q9UEW8	STK39	T60	T60M	60	Missense	central	0	yes	159.444	0.000	PhosphoSitePlus;EPSD	GDSC	61.825	Loss
STE_STE20_FRAY_STK39_ST	P55017	SLC12A3	Q9UEW8	STK39	T66	T60M	60	Missense	distal	-6	no	69.898	76.254	EPSD	GDSC	61.825	Up-regulation
STE_STE20_FRAY_STK39_ST	P55017	SLC12A3	Q9UEW8	STK39	T753	A749V	749	Missense	distal	-4	no	63.580	70.869	EPSD	GDSC;CCLE	61.825	Up-regulation
TKL_IRAK_IRAK1_ST	Q96FA3	PELI1	P51617	IRAK1	T80	T86N	86	Missense	distal	6	no	113.437	101.395	PhosphoSitePlus;EPSD	GDSC;CCLE	67.712	Down-regulation
TKL_IRAK_IRAK1_ST	Q96FA3	PELI1	P51617	IRAK1	S82	T86N	86	Missense	distal	4	no	122.719	120.271	EPSD;PhosphoSitePlus	GDSC;CCLE	67.712	Down-regulation
TKL_IRAK_IRAK1_ST	Q96FA3	PELI1	P51617	IRAK1	T86	T86N	86	Missense	central	0	yes	110.913	0.000	EPSD;PhosphoSitePlus	GDSC;CCLE	67.712	Loss
TKL_IRAK_IRAK1_ST	Q96FA3	PELI1	P51617	IRAK1	S125	D126A	126	Missense	proximal	1	no	117.669	117.724	EPSD;PhosphoSitePlus	GDSC;CCLE	67.712	Up-regulation
TKL_IRAK_IRAK1_ST	Q96FA3	PELI1	P51617	IRAK1	T127	D126A	126	Missense	proximal	-1	no	125.413	124.563	EPSD;PhosphoSitePlus	GDSC;CCLE	67.712	Down-regulation
TKL_IRAK_IRAK1_ST	Q96FA3	PELI1	P51617	IRAK1	T288	P292S	292	Missense	distal	4	no	130.428	130.557	EPSD;PhosphoSitePlus	GDSC;CCLE	67.712	Up-regulation
TKL_IRAK_IRAK1_ST	Q96FA3	PELI1	P51617	IRAK1	S293	P292S	292	Missense	proximal	-1	no	116.243	113.188	EPSD;PhosphoSitePlus	GDSC;CCLE	67.712	Down-regulation
TKL_IRAK_IRAK1_ST	P51617	IRAK1	P51617	IRAK1	S119	A125T	125	Missense	distal	6	no	77.258	69.822	EPSD	GDSC	67.712	Down-regulation
TKL_IRAK_IRAK1_ST	P51617	IRAK1	P51617	IRAK1	S131	A125T	125	Missense	distal	-6	no	80.572	68.677	EPSD	GDSC	67.712	Down-regulation
TKL_IRAK_IRAK1_ST	Q9HAT8	PELI2	P51617	IRAK1	S235	V239I	239	Missense	distal	4	no	78.469	76.488	EPSD	GDSC;CCLE	67.712	Down-regulation
TKL_IRAK_IRAK1_ST	Q9HAT8	PELI2	P51617	IRAK1	T237	V239I	239	Missense	proximal	2	no	68.495	62.486	EPSD	GDSC;CCLE	67.712	Loss
CMGC_CDKL_CDKL5_ST	Q9HCJ2	LRRC4C	O76039	CDKL5	S173	R170G	170	Missense	distal	-3	no	4.176	3.678	EPSD	GDSC;CCLE	2.968	Down-regulation
CMGC_CDKL_CDKL5_ST	Q9HCJ2	LRRC4C	O76039	CDKL5	S383	S378Y	378	Missense	distal	-5	no	2.790	3.282	EPSD	GDSC	2.968	Gain
CMGC_CDKL_CDKL5_ST	Q9UPN4	CEP131	O76039	CDKL5	T23	D19E	19	Missense	distal	-4	no	3.308	3.311	EPSD	GDSC	2.968	Up-regulation
CMGC_CDKL_CDKL5_ST	Q9UPN4	CEP131	O76039	CDKL5	S146	S144N	144	Missense	proximal	-2	no	2.145	3.020	EPSD	GDSC	2.968	Gain
CMGC_CDKL_CDKL5_ST	Q9UPN4	CEP131	O76039	CDKL5	S549	D545N	545	Missense	distal	-4	no	3.467	3.457	EPSD	GDSC	2.968	Down-regulation
CMGC_CDKL_CDKL5_ST	O76039	CDKL5	O76039	CDKL5	T169	E170*	170	Missense	proximal	1	no	12.683	12.625	EPSD;PhosphoSitePlus	GDSC	2.968	Down-regulation
CMGC_CDKL_CDKL5_ST	O76039	CDKL5	O76039	CDKL5	S526	P527S	527	Missense	proximal	1	no	2.979	2.937	EPSD	GDSC;CCLE	2.968	Loss
CMGC_CDKL_CDKL5_ST	O76039	CDKL5	O76039	CDKL5	S796	Q791P	791	Missense	distal	-5	no	3.186	3.522	EPSD	GDSC	2.968	Up-regulation
CMGC_CDKL_CDKL5_ST	O76039	CDKL5	O76039	CDKL5	T803	S810F	810	Missense	distal	7	no	2.974	3.007	EPSD	GDSC;CCLE	2.968	Up-regulation
CMGC_CDKL_CDKL5_ST	Q66K74	MAP1S	O76039	CDKL5	S321	G318S	318	Missense	distal	-3	no	4.124	4.137	EPSD	GDSC;CCLE	2.968	Up-regulation
CMGC_CDKL_CDKL5_ST	Q66K74	MAP1S	O76039	CDKL5	T925	K922N	922	Missense	distal	-3	no	5.304	5.070	EPSD	GDSC;CCLE	2.968	Down-regulation
CMGC_CDKL_CDKL5_ST	Q8TDM6	DLG5	O76039	CDKL5	S711	R707L	707	Missense	distal	-4	no	3.698	3.707	EPSD	GDSC;CCLE	2.968	Up-regulation
CMGC_CDKL_CDKL5_ST	Q8TDM6	DLG5	O76039	CDKL5	T849	F847L	847	Missense	proximal	-2	no	4.364	4.749	EPSD	GDSC	2.968	Up-regulation
CMGC_CDKL_CDKL5_ST	Q8TDM6	DLG5	O76039	CDKL5	S897	D898E	898	Missense	proximal	1	no	3.860	3.887	EPSD	GDSC;CCLE	2.968	Up-regulation
CMGC_CDKL_CDKL5_ST	Q8TDM6	DLG5	O76039	CDKL5	S897	R896H	896	Missense	proximal	-1	no	3.860	3.878	EPSD	GDSC	2.968	Up-regulation
CMGC_CDKL_CDKL5_ST	Q8TDM6	DLG5	O76039	CDKL5	S900	D898E	898	Missense	proximal	-2	no	3.768	3.794	EPSD	GDSC;CCLE	2.968	Up-regulation
CMGC_CDKL_CDKL5_ST	Q8TDM6	DLG5	O76039	CDKL5	S1118	R1111H	1111	Missense	distal	-7	no	4.571	5.506	EPSD	GDSC;CCLE	2.968	Up-regulation
CMGC_MAPK_p38_MAPK11_ST	P15336	ATF2	Q15759	MAPK11	T69	V63A	63	Missense	distal	-6	no	47.733	47.880	PhosphoSitePlus;EPSD	GDSC;CCLE	33.886	Up-regulation
CMGC_MAPK_p38_MAPK11_ST	P15336	ATF2	Q15759	MAPK11	S136	Q134H	134	Missense	proximal	-2	no	36.910	37.038	EPSD	GDSC;CCLE	33.886	Up-regulation
CMGC_MAPK_p38_MAPK11_ST	P15336	ATF2	Q15759	MAPK11	T325	H331L	331	Missense	distal	6	no	40.490	40.487	EPSD	GDSC;CCLE	33.886	Down-regulation
CMGC_MAPK_p38_MAPK11_ST	P15336	ATF2	Q15759	MAPK11	S328	H331L	331	Missense	distal	3	no	36.572	36.104	EPSD	GDSC;CCLE	33.886	Down-regulation
CMGC_MAPK_p38_MAPK11_ST	P15336	ATF2	Q15759	MAPK11	T333	H331L	331	Missense	proximal	-2	no	42.604	42.870	EPSD	GDSC;CCLE	33.886	Up-regulation
CMGC_MAPK_p38_MAPK11_ST	P04179	SOD2	Q15759	MAPK11	T79	A83V	83	Missense	distal	4	no	45.525	43.510	PhosphoSitePlus;EPSD	GDSC	33.886	Down-regulation
CMGC_MAPK_p38_MAPK11_ST	P04179	SOD2	Q15759	MAPK11	S106	E112G	112	Missense	distal	6	no	47.202	47.233	EPSD;PhosphoSitePlus	GDSC	33.886	Up-regulation
CMGC_MAPK_p38_MAPK11_ST	O00418	EEF2K	Q15759	MAPK11	S74	Y69H	69	Missense	distal	-5	no	41.457	41.342	EPSD	GDSC;CCLE	33.886	Down-regulation
CMGC_MAPK_p38_MAPK11_ST	Q00613	HSF1	Q15759	MAPK11	S292	R296H	296	Missense	distal	4	no	44.972	44.092	EPSD	GDSC;CCLE	33.886	Down-regulation
CMGC_MAPK_p38_MAPK11_ST	Q00613	HSF1	Q15759	MAPK11	S303	P308L	308	Missense	distal	5	no	47.052	46.955	EPSD;PhosphoSitePlus	GDSC	33.886	Down-regulation
CMGC_MAPK_p38_MAPK11_ST	Q00613	HSF1	Q15759	MAPK11	S303	R296H	296	Missense	distal	-7	no	47.052	46.943	EPSD;PhosphoSitePlus	GDSC;CCLE	33.886	Down-regulation
CMGC_MAPK_p38_MAPK11_ST	Q00613	HSF1	Q15759	MAPK11	S307	P308L	308	Missense	proximal	1	no	47.026	37.208	PhosphoSitePlus;EPSD	GDSC	33.886	Down-regulation
CMGC_MAPK_p38_MAPK11_ST	Q00613	HSF1	Q15759	MAPK11	S307	E312A	312	Missense	distal	5	no	47.026	46.634	PhosphoSitePlus;EPSD	GDSC	33.886	Down-regulation
CMGC_MAPK_p38_MAPK11_ST	Q00613	HSF1	Q15759	MAPK11	S314	P308L	308	Missense	distal	-6	no	37.205	37.144	EPSD	GDSC	33.886	Down-regulation
CMGC_MAPK_p38_MAPK11_ST	Q00613	HSF1	Q15759	MAPK11	S314	E312A	312	Missense	proximal	-2	no	37.205	37.249	EPSD	GDSC	33.886	Up-regulation
CMGC_MAPK_p38_MAPK11_ST	Q00613	HSF1	Q15759	MAPK11	T346	V345I	345	Missense	proximal	-1	no	35.196	34.741	EPSD	GDSC	33.886	Down-regulation
CMGC_MAPK_p38_MAPK11_ST	Q00613	HSF1	Q15759	MAPK11	S363	R360Q	360	Missense	distal	-3	no	44.089	43.915	EPSD	GDSC	33.886	Down-regulation
CMGC_MAPK_p38_MAPK11_ST	Q00613	HSF1	Q15759	MAPK11	S363	R360W	360	Missense	distal	-3	no	44.089	44.427	EPSD	GDSC;CCLE	33.886	Up-regulation
CMGC_MAPK_p38_MAPK11_ST	Q00613	HSF1	Q15759	MAPK11	S419	S419R	419	Missense	central	0	yes	42.318	0.000	EPSD	GDSC	33.886	Loss
CMGC_MAPK_p38_MAPK11_ST	Q00613	HSF1	Q15759	MAPK11	S419	S421W	421	Missense	proximal	2	no	42.318	40.702	EPSD	GDSC	33.886	Down-regulation
CMGC_MAPK_p38_MAPK11_ST	Q00613	HSF1	Q15759	MAPK11	S419	V422L	422	Missense	distal	3	no	42.318	42.391	EPSD	GDSC;CCLE	33.886	Up-regulation
CMGC_MAPK_p38_MAPK11_ST	Q00613	HSF1	Q15759	MAPK11	S458	S458I	458	Missense	central	0	yes	42.074	0.000	EPSD	GDSC;CCLE	33.886	Loss
CMGC_MAPK_p38_MAPK11_ST	Q8N122	RPTOR	Q15759	MAPK11	S696	L694F	694	Missense	proximal	-2	no	35.586	34.750	EPSD	GDSC;CCLE	33.886	Down-regulation
CMGC_MAPK_p38_MAPK11_ST	Q8N122	RPTOR	Q15759	MAPK11	S711	R716I	716	Missense	distal	5	no	44.879	45.408	EPSD	GDSC;CCLE	33.886	Up-regulation
CMGC_MAPK_p38_MAPK11_ST	Q8N122	RPTOR	Q15759	MAPK11	S711	R718H	718	Missense	distal	7	no	44.879	44.748	EPSD	GDSC;CCLE	33.886	Down-regulation
CMGC_MAPK_p38_MAPK11_ST	Q8N122	RPTOR	Q15759	MAPK11	T714	R716I	716	Missense	proximal	2	no	41.037	38.814	EPSD	GDSC;CCLE	33.886	Down-regulation
CMGC_MAPK_p38_MAPK11_ST	Q8N122	RPTOR	Q15759	MAPK11	T714	R718H	718	Missense	distal	4	no	41.037	40.157	EPSD	GDSC;CCLE	33.886	Down-regulation
CMGC_MAPK_p38_MAPK11_ST	Q8N122	RPTOR	Q15759	MAPK11	T731	S734N	734	Missense	distal	3	no	37.316	36.692	EPSD	GDSC;CCLE	33.886	Down-regulation
CMGC_MAPK_p38_MAPK11_ST	Q8N122	RPTOR	Q15759	MAPK11	S877	S881P	881	Missense	distal	4	no	36.051	35.647	EPSD	GDSC;CCLE	33.886	Down-regulation
CMGC_MAPK_p38_MAPK11_ST	Q8N122	RPTOR	Q15759	MAPK11	S887	S881P	881	Missense	distal	-6	no	42.638	42.543	EPSD	GDSC;CCLE	33.886	Down-regulation
CMGC_MAPK_p38_MAPK11_ST	Q8N122	RPTOR	Q15759	MAPK11	T917	Y916H	916	Missense	proximal	-1	no	46.103	45.634	EPSD	GDSC;CCLE	33.886	Down-regulation
CMGC_MAPK_p38_MAPK11_ST	Q01094	E2F1	Q15759	MAPK11	S307	G309E	309	Missense	proximal	2	no	34.651	35.301	EPSD	GDSC;CCLE	33.886	Up-regulation
CMGC_MAPK_p38_MAPK11_ST	Q01094	E2F1	Q15759	MAPK11	T311	G309E	309	Missense	proximal	-2	no	37.432	37.812	EPSD	GDSC;CCLE	33.886	Up-regulation
CMGC_MAPK_p38_MAPK11_ST	Q01094	E2F1	Q15759	MAPK11	S349	L351V	351	Missense	proximal	2	no	35.962	34.696	EPSD	GDSC;CCLE	33.886	Down-regulation
CMGC_MAPK_p38_MAPK11_ST	Q01094	E2F1	Q15759	MAPK11	S349	S349Y	349	Missense	central	0	yes	35.962	0.000	EPSD	GDSC;CCLE	33.886	Loss
CMGC_MAPK_p38_MAPK11_ST	Q01094	E2F1	Q15759	MAPK11	S352	P357Q	357	Missense	distal	5	no	35.108	34.910	EPSD	GDSC	33.886	Down-regulation
CMGC_MAPK_p38_MAPK11_ST	Q01094	E2F1	Q15759	MAPK11	S352	L351V	351	Missense	proximal	-1	no	35.108	34.755	EPSD	GDSC;CCLE	33.886	Down-regulation
CMGC_MAPK_p38_MAPK11_ST	Q01094	E2F1	Q15759	MAPK11	S352	S349Y	349	Missense	distal	-3	no	35.108	35.499	EPSD	GDSC;CCLE	33.886	Up-regulation
CMGC_MAPK_p38_MAPK11_ST	Q01094	E2F1	Q15759	MAPK11	S403	A408T	408	Missense	distal	5	no	47.567	47.958	EPSD;PhosphoSitePlus	GDSC;CCLE	33.886	Up-regulation
CMGC_MAPK_p38_MAPK11_ST	P00533	EGFR	Q15759	MAPK11	S227	N234D	234	Missense	distal	7	no	34.848	34.917	EPSD	GDSC;CCLE	33.886	Up-regulation
CMGC_MAPK_p38_MAPK11_ST	P00533	EGFR	Q15759	MAPK11	S645	I646L	646	Missense	proximal	1	no	-3.986	34.988	EPSD	GDSC;CCLE	33.886	Gain
CMGC_MAPK_p38_MAPK11_ST	P00533	EGFR	Q15759	MAPK11	S752	A750E	750	Missense	proximal	-2	no	45.508	45.465	EPSD	GDSC	33.886	Down-regulation
CMGC_MAPK_p38_MAPK11_ST	Q8IW41	MAPKAPK5	Q15759	MAPK11	S212	P213Q	213	Missense	proximal	1	no	39.481	7.339	EPSD	GDSC;CCLE	33.886	Loss
CMGC_MAPK_p38_MAPK11_ST	Q8IW41	MAPKAPK5	Q15759	MAPK11	S212	P215S	215	Missense	distal	3	no	39.481	39.945	EPSD	GDSC;CCLE	33.886	Up-regulation
CMGC_MAPK_p38_MAPK11_ST	Q8IW41	MAPKAPK5	Q15759	MAPK11	T214	P213Q	213	Missense	proximal	-1	no	41.160	41.026	EPSD	GDSC;CCLE	33.886	Down-regulation
CMGC_MAPK_p38_MAPK11_ST	Q8IW41	MAPKAPK5	Q15759	MAPK11	T214	P215S	215	Missense	proximal	1	no	41.160	25.661	EPSD	GDSC;CCLE	33.886	Loss
CMGC_MAPK_p38_MAPK11_ST	P30305	CDC25B	Q15759	MAPK11	S117	A124S	124	Missense	distal	7	no	43.493	44.192	EPSD	GDSC;CCLE	33.886	Up-regulation
CMGC_MAPK_p38_MAPK11_ST	P30305	CDC25B	Q15759	MAPK11	S160	V154A	154	Missense	distal	-6	no	34.688	34.835	EPSD	GDSC	33.886	Up-regulation
CMGC_MAPK_p38_MAPK11_ST	P30305	CDC25B	Q15759	MAPK11	S186	E179K	179	Missense	distal	-7	no	36.692	36.779	EPSD	GDSC	33.886	Up-regulation
CMGC_MAPK_p38_MAPK11_ST	P30305	CDC25B	Q15759	MAPK11	S186	E193Q	193	Missense	distal	7	no	36.692	36.061	EPSD	GDSC;CCLE	33.886	Down-regulation
CMGC_MAPK_p38_MAPK11_ST	P30305	CDC25B	Q15759	MAPK11	S375	R369C	369	Missense	distal	-6	no	37.282	37.089	EPSD	GDSC	33.886	Down-regulation
CMGC_MAPK_p38_MAPK11_ST	P30305	CDC25B	Q15759	MAPK11	S476	K479R	479	Missense	distal	3	no	38.233	37.354	EPSD	GDSC;CCLE	33.886	Down-regulation
CMGC_MAPK_p38_MAPK11_ST	P41235	HNF4A	Q15759	MAPK11	S167	N173D	173	Missense	distal	6	no	47.102	47.091	PhosphoSitePlus	GDSC;CCLE	33.886	Down-regulation
CMGC_MAPK_p38_MAPK11_ST	P41235	HNF4A	Q15759	MAPK11	S378	A385V	385	Missense	distal	7	no	41.933	41.542	EPSD	GDSC;CCLE	33.886	Down-regulation
CMGC_MAPK_p38_MAPK11_ST	P41235	HNF4A	Q15759	MAPK11	S378	P379H	379	Missense	proximal	1	no	41.933	0.872	EPSD	GDSC;CCLE	33.886	Loss
CMGC_MAPK_p38_MAPK11_ST	P17544	ATF7	Q15759	MAPK11	T51	Q50R	50	Missense	proximal	-1	no	48.874	48.932	PhosphoSitePlus	GDSC;CCLE	33.886	Up-regulation
CMGC_MAPK_p38_MAPK11_ST	P17544	ATF7	Q15759	MAPK11	T53	Q50R	50	Missense	distal	-3	no	52.229	52.403	EPSD	GDSC;CCLE	33.886	Up-regulation
CMGC_MAPK_p38_MAPK11_ST	P17544	ATF7	Q15759	MAPK11	S108	M107I	107	Missense	proximal	-1	no	33.895	32.959	EPSD	GDSC	33.886	Loss
CMGC_MAPK_p38_MAPK11_ST	P17544	ATF7	Q15759	MAPK11	T112	M107I	107	Missense	distal	-5	no	44.708	44.499	EPSD	GDSC	33.886	Down-regulation
CMGC_MAPK_p38_MAPK11_ST	P17544	ATF7	Q15759	MAPK11	S132	S136G	136	Missense	distal	4	no	36.141	35.867	EPSD	GDSC	33.886	Down-regulation
CMGC_MAPK_p38_MAPK11_ST	P17544	ATF7	Q15759	MAPK11	S136	S136G	136	Missense	central	0	yes	42.677	0.000	EPSD	GDSC	33.886	Loss
CMGC_MAPK_p38_MAPK11_ST	P17544	ATF7	Q15759	MAPK11	S139	S136G	136	Missense	distal	-3	no	40.831	40.634	EPSD	GDSC	33.886	Down-regulation
CMGC_MAPK_p38_MAPK11_ST	P17544	ATF7	Q15759	MAPK11	S315	S315P	315	Missense	central	0	yes	35.327	0.000	EPSD	GDSC	33.886	Loss
CMGC_MAPK_p38_MAPK11_ST	P17544	ATF7	Q15759	MAPK11	S322	S315P	315	Missense	distal	-7	no	41.778	41.639	EPSD	GDSC	33.886	Down-regulation
CMGC_MAPK_p38_MAPK11_ST	P17544	ATF7	Q15759	MAPK11	T486	P487S	487	Missense	proximal	1	no	36.749	21.250	EPSD	GDSC;CCLE	33.886	Loss
CMGC_MAPK_p38_MAPK11_ST	Q02156	PRKCE	Q15759	MAPK11	S329	P330L	330	Missense	proximal	1	no	42.861	33.044	EPSD	GDSC;CCLE	33.886	Loss
CMGC_MAPK_p38_MAPK11_ST	Q02156	PRKCE	Q15759	MAPK11	S337	P330L	330	Missense	distal	-7	no	34.854	34.768	EPSD	GDSC;CCLE	33.886	Down-regulation
CMGC_MAPK_p38_MAPK11_ST	Q02156	PRKCE	Q15759	MAPK11	S381	R377Q	377	Missense	distal	-4	no	48.729	46.930	EPSD	GDSC	33.886	Down-regulation
CMGC_MAPK_p38_MAPK11_ST	Q01844	EWSR1	Q15759	MAPK11	S259	Q256*	256	Missense	distal	-3	no	34.104	34.889	EPSD	GDSC	33.886	Up-regulation
CMGC_MAPK_p38_MAPK11_ST	P30281	CCND3	Q15759	MAPK11	S133	P134S	134	Missense	proximal	1	no	42.758	27.259	EPSD	GDSC	33.886	Loss
CMGC_MAPK_p38_MAPK11_ST	P04150	NR3C1	Q15759	MAPK11	S340	Y334*	334	Missense	distal	-6	no	36.454	36.217	EPSD	GDSC	33.886	Down-regulation
TK_EGFR_ERBB4_Y	Q15303	ERBB4	Q15303	ERBB4	Y1081	Y1081N	1081	Missense	central	0	yes	0.000	0.000	EPSD	GDSC;CCLE	0.000	Loss
Other_NKF2_PINK1_ST	Q9BXM7	PINK1	Q9BXM7	PINK1	S402	P399L	399	Missense	distal	-3	no	24.684	24.849	PhosphoSitePlus;EPSD	GDSC;CCLE	11.649	Up-regulation
Other_NKF2_PINK1_ST	Q8IXI2	RHOT1	Q9BXM7	PINK1	S156	Q163*	163	Missense	distal	7	no	26.785	27.550	PhosphoSitePlus	GDSC	11.649	Up-regulation
Other_NKF2_PINK1_ST	O60260	PRKN	Q9BXM7	PINK1	S65	I69V	69	Missense	distal	4	no	27.647	27.433	PhosphoSitePlus	GDSC	11.649	Down-regulation
TKL_RAF_RAF_RAF1_ST	P04049	RAF1	P04049	RAF1	T182	D186V	186	Missense	distal	4	no	7.941	8.308	EPSD	GDSC;CCLE	7.934	Up-regulation
TKL_RAF_RAF_RAF1_ST	P04049	RAF1	P04049	RAF1	S204	P207S	207	Missense	distal	3	no	10.128	8.966	EPSD	GDSC;CCLE	7.934	Down-regulation
TKL_RAF_RAF_RAF1_ST	P04049	RAF1	P04049	RAF1	S211	P207S	207	Missense	distal	-4	no	6.132	9.398	EPSD	GDSC;CCLE	7.934	Gain
TKL_RAF_RAF_RAF1_ST	P04049	RAF1	P04049	RAF1	S220	V226I	226	Missense	distal	6	no	8.780	8.830	EPSD	GDSC;CCLE	7.934	Up-regulation
TKL_RAF_RAF_RAF1_ST	P04049	RAF1	P04049	RAF1	S227	V226I	226	Missense	proximal	-1	no	8.404	8.466	EPSD	GDSC;CCLE	7.934	Up-regulation
TKL_RAF_RAF_RAF1_ST	P04049	RAF1	P04049	RAF1	S257	Q253P	253	Missense	distal	-4	no	11.654	9.665	EPSD	GDSC	7.934	Down-regulation
TKL_RAF_RAF_RAF1_ST	P04049	RAF1	P04049	RAF1	S259	Q253P	253	Missense	distal	-6	no	15.532	15.857	EPSD;PhosphoSitePlus	GDSC	7.934	Up-regulation
TKL_RAF_RAF_RAF1_ST	P04049	RAF1	P04049	RAF1	S338	E343G	343	Missense	distal	5	no	14.086	14.301	EPSD;PhosphoSitePlus	GDSC;CCLE	7.934	Up-regulation
TKL_RAF_RAF_RAF1_ST	P04049	RAF1	P04049	RAF1	S621	P614L	614	Missense	distal	-7	no	15.150	15.201	PhosphoSitePlus;EPSD	GDSC;CCLE	7.934	Up-regulation
TKL_RAF_RAF_RAF1_ST	Q13118	KLF10	P04049	RAF1	T93	L92F	92	Missense	proximal	-1	no	13.824	13.651	PhosphoSitePlus	GDSC;CCLE	7.934	Down-regulation
TKL_RAF_RAF_RAF1_ST	Q13118	KLF10	P04049	RAF1	S353	Q360E	360	Missense	distal	7	no	8.658	9.342	EPSD	GDSC;CCLE	7.934	Up-regulation
TKL_RAF_RAF_RAF1_ST	Q13118	KLF10	P04049	RAF1	T394	T390M	390	Missense	distal	-4	no	8.435	8.404	EPSD	GDSC	7.934	Down-regulation
TKL_RAF_RAF_RAF1_ST	Q92934	BAD	P04049	RAF1	S134	T137K	137	Missense	distal	3	no	8.211	8.477	EPSD	GDSC	7.934	Up-regulation
TKL_RAF_RAF_RAF1_ST	Q92934	BAD	P04049	RAF1	S134	L129F	129	Missense	distal	-5	no	8.211	7.992	EPSD	GDSC	7.934	Down-regulation
TKL_RAF_RAF_RAF1_ST	Q92934	BAD	P04049	RAF1	S144	F151L	151	Missense	distal	7	no	12.633	12.079	EPSD	GDSC;CCLE	7.934	Down-regulation
TKL_RAF_RAF_RAF1_ST	Q92934	BAD	P04049	RAF1	S144	T137K	137	Missense	distal	-7	no	12.633	12.618	EPSD	GDSC	7.934	Down-regulation
TKL_RAF_RAF_RAF1_ST	Q92934	BAD	P04049	RAF1	T148	F151L	151	Missense	distal	3	no	8.089	7.561	EPSD	GDSC;CCLE	7.934	Loss
TKL_RAF_RAF_RAF1_ST	Q05639	EEF1A2	P04049	RAF1	S21	T22I	22	Missense	proximal	1	no	12.629	12.728	PhosphoSitePlus	GDSC;CCLE	7.934	Up-regulation
TKL_RAF_RAF_RAF1_ST	O14974	PPP1R12A	P04049	RAF1	S585	S589T	589	Missense	distal	4	no	9.716	8.719	EPSD	GDSC;CCLE	7.934	Down-regulation
TKL_RAF_RAF_RAF1_ST	O14974	PPP1R12A	P04049	RAF1	S716	R720T	720	Missense	distal	4	no	7.331	8.104	EPSD	GDSC;CCLE	7.934	Gain
TKL_RAF_RAF_RAF1_ST	O14974	PPP1R12A	P04049	RAF1	S759	R760T	760	Missense	proximal	1	no	9.199	9.321	EPSD	GDSC;CCLE	7.934	Up-regulation
TKL_RAF_RAF_RAF1_ST	O14974	PPP1R12A	P04049	RAF1	S995	R993K	993	Missense	proximal	-2	no	8.713	8.710	EPSD	GDSC;CCLE	7.934	Down-regulation
CAMK_MAPKAPK_MK2_MAPKAPK2_ST	Q8N5C8	TAB3	P49137	MAPKAPK2	S82	G87*	87	Missense	distal	5	no	12.230	12.322	EPSD	GDSC	11.681	Up-regulation
CAMK_MAPKAPK_MK2_MAPKAPK2_ST	Q8N5C8	TAB3	P49137	MAPKAPK2	S103	H100Q	100	Missense	distal	-3	no	12.834	11.830	EPSD	GDSC;CCLE	11.681	Down-regulation
CAMK_MAPKAPK_MK2_MAPKAPK2_ST	Q8N5C8	TAB3	P49137	MAPKAPK2	S356	L351I	351	Missense	distal	-5	no	12.174	11.986	EPSD	GDSC;CCLE	11.681	Down-regulation
CAMK_MAPKAPK_MK2_MAPKAPK2_ST	Q8N5C8	TAB3	P49137	MAPKAPK2	S357	L351I	351	Missense	distal	-6	no	12.050	12.057	EPSD	GDSC;CCLE	11.681	Up-regulation
CAMK_MAPKAPK_MK2_MAPKAPK2_ST	Q8N5C8	TAB3	P49137	MAPKAPK2	S409	S408N	408	Missense	proximal	-1	no	15.751	15.766	EPSD	GDSC;CCLE	11.681	Up-regulation
CAMK_MAPKAPK_MK2_MAPKAPK2_ST	Q8N5C8	TAB3	P49137	MAPKAPK2	S411	S408N	408	Missense	distal	-3	no	12.529	12.313	EPSD	GDSC;CCLE	11.681	Down-regulation
CAMK_MAPKAPK_MK2_MAPKAPK2_ST	Q8N5C8	TAB3	P49137	MAPKAPK2	S415	S408N	408	Missense	distal	-7	no	17.875	17.925	EPSD	GDSC;CCLE	11.681	Up-regulation
CAMK_MAPKAPK_MK2_MAPKAPK2_ST	Q8N5C8	TAB3	P49137	MAPKAPK2	S444	T440A	440	Missense	distal	-4	no	15.072	15.197	EPSD	GDSC;CCLE	11.681	Up-regulation
CAMK_MAPKAPK_MK2_MAPKAPK2_ST	Q8N5C8	TAB3	P49137	MAPKAPK2	S563	R561S	561	Missense	proximal	-2	no	17.200	19.467	EPSD	GDSC;CCLE	11.681	Up-regulation
CAMK_MAPKAPK_MK2_MAPKAPK2_ST	P30305	CDC25B	P49137	MAPKAPK2	S91	R93Q	93	Missense	proximal	2	no	13.750	13.446	EPSD	GDSC;CCLE	11.681	Down-regulation
CAMK_MAPKAPK_MK2_MAPKAPK2_ST	P30305	CDC25B	P49137	MAPKAPK2	S91	S89T	89	Missense	proximal	-2	no	13.750	11.996	EPSD	GDSC;CCLE	11.681	Down-regulation
CAMK_MAPKAPK_MK2_MAPKAPK2_ST	P30305	CDC25B	P49137	MAPKAPK2	S117	A124S	124	Missense	distal	7	no	13.328	13.128	EPSD	GDSC;CCLE	11.681	Down-regulation
CAMK_MAPKAPK_MK2_MAPKAPK2_ST	P30305	CDC25B	P49137	MAPKAPK2	S151	V154A	154	Missense	distal	3	no	12.970	13.075	EPSD	GDSC	11.681	Up-regulation
CAMK_MAPKAPK_MK2_MAPKAPK2_ST	P30305	CDC25B	P49137	MAPKAPK2	S178	E179K	179	Missense	proximal	1	no	17.061	16.596	EPSD	GDSC	11.681	Down-regulation
CAMK_MAPKAPK_MK2_MAPKAPK2_ST	P30305	CDC25B	P49137	MAPKAPK2	S375	R369C	369	Missense	distal	-6	no	19.277	19.327	EPSD;PhosphoSitePlus	GDSC	11.681	Up-regulation
CAMK_MAPKAPK_MK2_MAPKAPK2_ST	P17302	GJA1	P49137	MAPKAPK2	S296	G291D	291	Missense	distal	-5	no	16.244	16.348	EPSD	GDSC;CCLE	11.681	Up-regulation
CAMK_MAPKAPK_MK2_MAPKAPK2_ST	P17302	GJA1	P49137	MAPKAPK2	S296	R299C	299	Missense	distal	3	no	16.244	16.194	EPSD	GDSC;CCLE	11.681	Down-regulation
CAMK_MAPKAPK_MK2_MAPKAPK2_ST	P17302	GJA1	P49137	MAPKAPK2	S296	V289G	289	Missense	distal	-7	no	16.244	16.268	EPSD	GDSC;CCLE	11.681	Up-regulation
CAMK_MAPKAPK_MK2_MAPKAPK2_ST	P17302	GJA1	P49137	MAPKAPK2	S296	D292G	292	Missense	distal	-4	no	16.244	16.322	EPSD	GDSC;CCLE	11.681	Up-regulation
CAMK_MAPKAPK_MK2_MAPKAPK2_ST	P04792	HSPB1	P49137	MAPKAPK2	S158	S155P	155	Missense	distal	-3	no	13.817	15.482	EPSD	GDSC;CCLE	11.681	Up-regulation
CAMK_MAPKAPK_MK2_MAPKAPK2_ST	Q96J92	WNK4	P49137	MAPKAPK2	S47	R41G	41	Missense	distal	-6	no	16.734	16.806	EPSD	GDSC;CCLE	11.681	Up-regulation
CAMK_MAPKAPK_MK2_MAPKAPK2_ST	Q96J92	WNK4	P49137	MAPKAPK2	S680	R675W	675	Missense	distal	-5	no	16.618	16.263	EPSD	GDSC;CCLE	11.681	Down-regulation
CAMK_MAPKAPK_MK2_MAPKAPK2_ST	Q96J92	WNK4	P49137	MAPKAPK2	S682	R675W	675	Missense	distal	-7	no	12.775	12.853	EPSD	GDSC;CCLE	11.681	Up-regulation
CAMK_MAPKAPK_MK2_MAPKAPK2_ST	Q6JBY9	RCSD1	P49137	MAPKAPK2	S50	R44Q	44	Missense	distal	-6	no	12.794	12.848	EPSD	GDSC;CCLE	11.681	Up-regulation
CAMK_MAPKAPK_MK2_MAPKAPK2_ST	Q6JBY9	RCSD1	P49137	MAPKAPK2	S50	P56S	56	Missense	distal	6	no	12.794	12.811	EPSD	GDSC;CCLE	11.681	Up-regulation
CAMK_MAPKAPK_MK2_MAPKAPK2_ST	Q6JBY9	RCSD1	P49137	MAPKAPK2	S50	P56A	56	Missense	distal	6	no	12.794	12.801	EPSD	GDSC	11.681	Up-regulation
CAMK_MAPKAPK_MK2_MAPKAPK2_ST	Q6JBY9	RCSD1	P49137	MAPKAPK2	S123	S120R	120	Missense	distal	-3	no	9.872	16.201	EPSD	GDSC;CCLE	11.681	Gain
CAMK_MAPKAPK_MK2_MAPKAPK2_ST	Q6JBY9	RCSD1	P49137	MAPKAPK2	S211	L207W	207	Missense	distal	-4	no	13.244	13.270	EPSD	GDSC	11.681	Up-regulation
CAMK_MAPKAPK_MK2_MAPKAPK2_ST	Q9UKV8	AGO2	P49137	MAPKAPK2	S798	A801E	801	Missense	distal	3	no	17.334	17.272	EPSD	GDSC;CCLE	11.681	Down-regulation
CAMK_MAPKAPK_MK2_MAPKAPK2_ST	O95816	BAG2	P49137	MAPKAPK2	S73	S66N	66	Missense	distal	-7	no	13.310	13.360	EPSD	GDSC;CCLE	11.681	Up-regulation
CAMK_MAPKAPK_MK2_MAPKAPK2_ST	Q9Y580	RBM7	P49137	MAPKAPK2	S155	K159I	159	Missense	distal	4	no	15.293	15.345	EPSD	GDSC;CCLE	11.681	Up-regulation
CAMK_MAPKAPK_MK2_MAPKAPK2_ST	Q9Y580	RBM7	P49137	MAPKAPK2	S155	M154L	154	Missense	proximal	-1	no	15.293	15.285	EPSD	GDSC;CCLE	11.681	Down-regulation
CAMK_MAPKAPK_MK2_MAPKAPK2_ST	Q9Y580	RBM7	P49137	MAPKAPK2	S155	M154K	154	Missense	proximal	-1	no	15.293	15.296	EPSD	GDSC;CCLE	11.681	Up-regulation
CAMK_MAPKAPK_MK2_MAPKAPK2_ST	O00418	EEF2K	P49137	MAPKAPK2	S66	Y69H	69	Missense	distal	3	no	12.392	12.437	EPSD	GDSC;CCLE	11.681	Up-regulation
CAMK_MAPKAPK_MK2_MAPKAPK2_ST	O00418	EEF2K	P49137	MAPKAPK2	S71	Y69H	69	Missense	proximal	-2	no	13.537	13.710	EPSD	GDSC;CCLE	11.681	Up-regulation
CAMK_MAPKAPK_MK2_MAPKAPK2_ST	O00418	EEF2K	P49137	MAPKAPK2	S72	Y69H	69	Missense	distal	-3	no	11.866	12.848	EPSD	GDSC;CCLE	11.681	Up-regulation
CAMK_MAPKAPK_MK2_MAPKAPK2_ST	O00418	EEF2K	P49137	MAPKAPK2	S500	H495P	495	Missense	distal	-5	no	11.595	11.909	EPSD	GDSC	11.681	Gain
CAMK_MAPKAPK_MK2_MAPKAPK2_ST	P05783	KRT18	P49137	MAPKAPK2	S127	H128L	128	Missense	proximal	1	no	12.738	13.304	EPSD	GDSC	11.681	Up-regulation
CAMK_MAPKAPK_MK2_MAPKAPK2_ST	Q07352	ZFP36L1	P49137	MAPKAPK2	T148	L144F	144	Missense	distal	-4	no	14.848	15.039	EPSD	GDSC;CCLE	11.681	Up-regulation
CAMK_MAPKAPK_MK2_MAPKAPK2_ST	Q9NQC3	RTN4	P49137	MAPKAPK2	S239	L238V	238	Missense	proximal	-1	no	13.945	13.947	EPSD	GDSC;CCLE	11.681	Up-regulation
CAMK_MAPKAPK_MK2_MAPKAPK2_ST	Q9NQC3	RTN4	P49137	MAPKAPK2	S245	L238V	238	Missense	distal	-7	no	11.788	11.790	EPSD	GDSC;CCLE	11.681	Up-regulation
CAMK_MAPKAPK_MK2_MAPKAPK2_ST	Q9NQC3	RTN4	P49137	MAPKAPK2	S440	S440N	440	Missense	central	0	yes	12.476	0.000	EPSD	GDSC	11.681	Loss
CAMK_MAPKAPK_MK2_MAPKAPK2_ST	P53350	PLK1	P49137	MAPKAPK2	S565	E568*	568	Missense	distal	3	no	12.059	11.877	EPSD	GDSC	11.681	Down-regulation
CAMK_MAPKAPK_MK2_MAPKAPK2_ST	Q9UPN4	CEP131	P49137	MAPKAPK2	T23	D19E	19	Missense	distal	-4	no	11.711	11.539	EPSD	GDSC	11.681	Loss
CAMK_MAPKAPK_MK2_MAPKAPK2_ST	Q9UPN4	CEP131	P49137	MAPKAPK2	S89	E94Q	94	Missense	distal	5	no	18.455	18.601	EPSD	GDSC	11.681	Up-regulation
CAMK_MAPKAPK_MK2_MAPKAPK2_ST	Q9UPN4	CEP131	P49137	MAPKAPK2	S114	S114N	114	Missense	central	0	yes	15.748	0.000	EPSD	GDSC	11.681	Loss
CAMK_MAPKAPK_MK2_MAPKAPK2_ST	Q9UPN4	CEP131	P49137	MAPKAPK2	S120	S114N	114	Missense	distal	-6	no	12.275	12.347	EPSD	GDSC	11.681	Up-regulation
CAMK_MAPKAPK_MK2_MAPKAPK2_ST	Q9UPN4	CEP131	P49137	MAPKAPK2	S146	S144N	144	Missense	proximal	-2	no	16.590	14.226	EPSD	GDSC	11.681	Down-regulation
CAMK_MAPKAPK_MK2_MAPKAPK2_ST	Q9UPN4	CEP131	P49137	MAPKAPK2	S416	L411Q	411	Missense	distal	-5	no	15.297	14.238	EPSD	GDSC	11.681	Down-regulation
CAMK_MAPKAPK_MK2_MAPKAPK2_ST	P31749	AKT1	P49137	MAPKAPK2	S473	G478S	478	Missense	distal	5	no	12.620	12.331	PhosphoSitePlus	GDSC;CCLE	11.681	Down-regulation
CAMK_MAPKAPK_MK2_MAPKAPK2_ST	P31749	AKT1	P49137	MAPKAPK2	S477	G478S	478	Missense	proximal	1	no	12.069	12.489	EPSD	GDSC;CCLE	11.681	Up-regulation
CAMK_MAPKAPK_MK2_MAPKAPK2_ST	O15511	ARPC5	P49137	MAPKAPK2	S77	A70T	70	Missense	distal	-7	no	16.791	16.771	PhosphoSitePlus	GDSC;CCLE	11.681	Down-regulation
CAMK_MAPKAPK_MK2_MAPKAPK2_ST	P04637	TP53	P49137	MAPKAPK2	S183	S183*	183	Missense	central	0	yes	12.691	0.000	EPSD	GDSC	11.681	Loss
CAMK_MAPKAPK_MK2_MAPKAPK2_ST	P04637	TP53	P49137	MAPKAPK2	S183	E180*	180	Missense	distal	-3	no	12.691	9.752	EPSD	GDSC	11.681	Loss
CAMK_MAPKAPK_MK2_MAPKAPK2_ST	P04637	TP53	P49137	MAPKAPK2	S314	Q317*	317	Missense	distal	3	no	12.556	12.523	EPSD	GDSC	11.681	Down-regulation
CAMK_MAPKAPK_MK2_MAPKAPK2_ST	P04637	TP53	P49137	MAPKAPK2	S314	K319*	319	Missense	distal	5	no	12.556	12.632	EPSD	GDSC	11.681	Up-regulation
CAMK_MAPKAPK_MK2_MAPKAPK2_ST	P04637	TP53	P49137	MAPKAPK2	S315	Q317*	317	Missense	proximal	2	no	12.896	12.692	EPSD	GDSC	11.681	Down-regulation
CAMK_MAPKAPK_MK2_MAPKAPK2_ST	P04637	TP53	P49137	MAPKAPK2	S315	K319*	319	Missense	distal	4	no	12.896	12.836	EPSD	GDSC	11.681	Down-regulation
CAMK_MAPKAPK_MK2_MAPKAPK2_ST	P04637	TP53	P49137	MAPKAPK2	S366	G360V	360	Missense	distal	-6	no	15.431	15.390	EPSD	GDSC;CCLE	11.681	Down-regulation
CAMK_MAPKAPK_MK2_MAPKAPK2_ST	Q14134	TRIM29	P49137	MAPKAPK2	S21	R20Q	20	Missense	proximal	-1	no	12.763	12.787	EPSD	GDSC;CCLE	11.681	Up-regulation
CAMK_MAPKAPK_MK2_MAPKAPK2_ST	Q14134	TRIM29	P49137	MAPKAPK2	S23	R20Q	20	Missense	distal	-3	no	18.844	13.081	EPSD	GDSC;CCLE	11.681	Down-regulation
CAMK_MAPKAPK_MK2_MAPKAPK2_ST	Q14134	TRIM29	P49137	MAPKAPK2	S256	K253R	253	Missense	distal	-3	no	11.221	16.345	EPSD	GDSC;CCLE	11.681	Gain
CAMK_MAPKAPK_MK2_MAPKAPK2_ST	Q14134	TRIM29	P49137	MAPKAPK2	S301	K294M	294	Missense	distal	-7	no	14.704	14.693	EPSD	GDSC;CCLE	11.681	Down-regulation
CAMK_MAPKAPK_MK2_MAPKAPK2_ST	Q14134	TRIM29	P49137	MAPKAPK2	S472	G479S	479	Missense	distal	7	no	12.203	12.408	EPSD	GDSC	11.681	Up-regulation
CAMK_MAPKAPK_MK2_MAPKAPK2_ST	Q14134	TRIM29	P49137	MAPKAPK2	S550	P557H	557	Missense	distal	7	no	13.078	12.525	PhosphoSitePlus;EPSD	GDSC;CCLE	11.681	Down-regulation
CAMK_MAPKAPK_MK2_MAPKAPK2_ST	Q14134	TRIM29	P49137	MAPKAPK2	S552	P557H	557	Missense	distal	5	no	19.038	19.280	EPSD;PhosphoSitePlus	GDSC;CCLE	11.681	Up-regulation
CAMK_MAPKAPK_MK2_MAPKAPK2_ST	O95453	PARN	P49137	MAPKAPK2	S167	V171A	171	Missense	distal	4	no	12.562	12.712	EPSD	GDSC;CCLE	11.681	Up-regulation
CAMK_MAPKAPK_MK2_MAPKAPK2_ST	O95453	PARN	P49137	MAPKAPK2	S342	L343I	343	Missense	proximal	1	no	12.180	12.077	EPSD	GDSC;CCLE	11.681	Down-regulation
CAMK_MAPKAPK_MK2_MAPKAPK2_ST	O95453	PARN	P49137	MAPKAPK2	T527	S530I	530	Missense	distal	3	no	12.253	12.144	EPSD	GDSC;CCLE	11.681	Down-regulation
CAMK_MAPKAPK_MK2_MAPKAPK2_ST	O95453	PARN	P49137	MAPKAPK2	S623	G622E	622	Missense	proximal	-1	no	13.123	13.107	EPSD	GDSC	11.681	Down-regulation
CAMK_MAPKAPK_MK2_MAPKAPK2_ST	O95453	PARN	P49137	MAPKAPK2	S625	G622E	622	Missense	distal	-3	no	7.360	12.724	EPSD	GDSC	11.681	Gain
CAMK_MAPKAPK_MK2_MAPKAPK2_ST	P17844	DDX5	P49137	MAPKAPK2	S279	E285*	285	Missense	distal	6	no	11.872	11.850	EPSD	GDSC	11.681	Down-regulation
CAMK_MAPKAPK_MK2_MAPKAPK2_ST	Q92904	DAZL	P49137	MAPKAPK2	S65	S58R	58	Missense	distal	-7	no	14.833	14.798	PhosphoSitePlus	GDSC;CCLE	11.681	Down-regulation
CAMK_MAPKAPK_MK2_MAPKAPK2_ST	Q13546	RIPK1	P49137	MAPKAPK2	S416	R413H	413	Missense	distal	-3	no	14.768	10.009	EPSD	GDSC;CCLE	11.681	Loss
CAMK_MAPKAPK_MK2_MAPKAPK2_ST	P11831	SRF	P49137	MAPKAPK2	S189	V183G	183	Missense	distal	-6	no	12.735	12.775	EPSD	GDSC;CCLE	11.681	Up-regulation
CAMK_MAPKAPK_MK2_MAPKAPK2_ST	P11831	SRF	P49137	MAPKAPK2	S189	E190K	190	Missense	proximal	1	no	12.735	12.270	EPSD	GDSC;CCLE	11.681	Down-regulation
CAMK_MAPKAPK_MK2_MAPKAPK2_ST	P11831	SRF	P49137	MAPKAPK2	S251	S253C	253	Missense	proximal	2	no	12.468	12.069	EPSD	GDSC;CCLE	11.681	Down-regulation
CAMK_MAPKAPK_MK2_MAPKAPK2_ST	Q13263	TRIM28	P49137	MAPKAPK2	S285	R282C	282	Missense	distal	-3	no	16.286	7.886	EPSD	GDSC;CCLE	11.681	Loss
CAMK_MAPKAPK_MK2_MAPKAPK2_ST	Q13263	TRIM28	P49137	MAPKAPK2	S473	S471F	471	Missense	proximal	-2	no	19.200	13.774	PhosphoSitePlus	GDSC;CCLE	11.681	Down-regulation
CAMK_MAPKAPK_MK2_MAPKAPK2_ST	Q13263	TRIM28	P49137	MAPKAPK2	S501	Q502H	502	Missense	proximal	1	no	12.041	12.105	EPSD	GDSC;CCLE	11.681	Up-regulation
CAMK_MAPKAPK_MK2_MAPKAPK2_ST	Q13263	TRIM28	P49137	MAPKAPK2	S501	V505I	505	Missense	distal	4	no	12.041	11.981	EPSD	GDSC;CCLE	11.681	Down-regulation
CAMK_MAPKAPK_MK2_MAPKAPK2_ST	Q13263	TRIM28	P49137	MAPKAPK2	S594	S601L	601	Missense	distal	7	no	14.830	14.474	EPSD	GDSC;CCLE	11.681	Down-regulation
CAMK_MAPKAPK_MK2_MAPKAPK2_ST	Q13263	TRIM28	P49137	MAPKAPK2	S598	V605G	605	Missense	distal	7	no	14.103	14.122	EPSD	GDSC	11.681	Up-regulation
CAMK_MAPKAPK_MK2_MAPKAPK2_ST	Q13263	TRIM28	P49137	MAPKAPK2	S598	S601L	601	Missense	distal	3	no	14.103	13.988	EPSD	GDSC;CCLE	11.681	Down-regulation
CAMK_MAPKAPK_MK2_MAPKAPK2_ST	P33241	LSP1	P49137	MAPKAPK2	S177	Q171P	171	Missense	distal	-6	no	17.187	17.120	EPSD	GDSC;CCLE	11.681	Down-regulation
CAMK_MAPKAPK_MK2_MAPKAPK2_ST	P33241	LSP1	P49137	MAPKAPK2	S204	R207H	207	Missense	distal	3	no	18.238	18.101	EPSD	GDSC;CCLE	11.681	Down-regulation
CAMK_MAPKAPK_MK2_MAPKAPK2_ST	P33241	LSP1	P49137	MAPKAPK2	S214	R207H	207	Missense	distal	-7	no	13.750	13.841	EPSD	GDSC;CCLE	11.681	Up-regulation
CAMK_MAPKAPK_MK2_MAPKAPK2_ST	P33241	LSP1	P49137	MAPKAPK2	S252	L255M	255	Missense	distal	3	no	19.119	19.169	PhosphoSitePlus	GDSC	11.681	Up-regulation
CAMK_MAPKAPK_MK2_MAPKAPK2_ST	P33241	LSP1	P49137	MAPKAPK2	S252	R249L	249	Missense	distal	-3	no	19.119	14.029	PhosphoSitePlus	GDSC;CCLE	11.681	Down-regulation
CAMK_MAPKAPK_MK2_MAPKAPK2_ST	P33241	LSP1	P49137	MAPKAPK2	S252	P256S	256	Missense	distal	4	no	19.119	19.178	PhosphoSitePlus	GDSC	11.681	Up-regulation
CAMK_MAPKAPK_MK2_MAPKAPK2_ST	P33241	LSP1	P49137	MAPKAPK2	S257	L255M	255	Missense	proximal	-2	no	12.185	13.416	EPSD	GDSC	11.681	Up-regulation
CAMK_MAPKAPK_MK2_MAPKAPK2_ST	P33241	LSP1	P49137	MAPKAPK2	S257	P256S	256	Missense	proximal	-1	no	12.185	12.184	EPSD	GDSC	11.681	Down-regulation
CAMK_MAPKAPK_MK2_MAPKAPK2_ST	O75925	PIAS1	P49137	MAPKAPK2	S92	S92F	92	Missense	central	0	yes	13.120	0.000	EPSD	GDSC	11.681	Loss
CAMK_MAPKAPK_MK2_MAPKAPK2_ST	O75925	PIAS1	P49137	MAPKAPK2	S106	S106P	106	Missense	central	0	yes	12.369	0.000	EPSD	GDSC;CCLE	11.681	Loss
CAMK_MAPKAPK_MK2_MAPKAPK2_ST	O75925	PIAS1	P49137	MAPKAPK2	S451	S446T	446	Missense	distal	-5	no	12.877	12.795	EPSD	GDSC;CCLE	11.681	Down-regulation
CAMK_MAPKAPK_MK2_MAPKAPK2_ST	O75925	PIAS1	P49137	MAPKAPK2	S503	S497R	497	Missense	distal	-6	no	11.873	11.886	EPSD	GDSC;CCLE	11.681	Up-regulation
CAMK_MAPKAPK_MK2_MAPKAPK2_ST	O75925	PIAS1	P49137	MAPKAPK2	S503	V505A	505	Missense	proximal	2	no	11.873	12.179	EPSD	GDSC;CCLE	11.681	Up-regulation
CAMK_MAPKAPK_MK2_MAPKAPK2_ST	O75925	PIAS1	P49137	MAPKAPK2	S510	V505A	505	Missense	distal	-5	no	17.412	16.741	EPSD	GDSC;CCLE	11.681	Down-regulation
CAMK_MAPKAPK_MK2_MAPKAPK2_ST	Q9NY61	AATF	P49137	MAPKAPK2	S155	K162R	162	Missense	distal	7	no	14.094	14.318	EPSD	GDSC;CCLE	11.681	Up-regulation
CAMK_MAPKAPK_MK2_MAPKAPK2_ST	Q9NY61	AATF	P49137	MAPKAPK2	T366	R363M	363	Missense	distal	-3	no	12.539	4.148	PhosphoSitePlus	GDSC;CCLE	11.681	Loss
CAMK_MAPKAPK_MK2_MAPKAPK2_ST	Q9NY61	AATF	P49137	MAPKAPK2	T366	T366A	366	Missense	central	0	yes	12.539	0.000	PhosphoSitePlus	GDSC;CCLE	11.681	Loss
CAMK_MAPKAPK_MK2_MAPKAPK2_ST	Q00613	HSF1	P49137	MAPKAPK2	S290	R296H	296	Missense	distal	6	no	15.437	15.406	EPSD	GDSC;CCLE	11.681	Down-regulation
CAMK_MAPKAPK_MK2_MAPKAPK2_ST	Q00613	HSF1	P49137	MAPKAPK2	S292	R296H	296	Missense	distal	4	no	15.145	14.906	EPSD	GDSC;CCLE	11.681	Down-regulation
CAMK_MAPKAPK_MK2_MAPKAPK2_ST	Q00613	HSF1	P49137	MAPKAPK2	S303	P308L	308	Missense	distal	5	no	11.597	11.684	EPSD	GDSC	11.681	Gain
CAMK_MAPKAPK_MK2_MAPKAPK2_ST	Q00613	HSF1	P49137	MAPKAPK2	S303	R296H	296	Missense	distal	-7	no	11.597	11.688	EPSD	GDSC;CCLE	11.681	Gain
CAMK_MAPKAPK_MK2_MAPKAPK2_ST	Q00613	HSF1	P49137	MAPKAPK2	S307	P308L	308	Missense	proximal	1	no	12.426	12.517	EPSD	GDSC	11.681	Up-regulation
CAMK_MAPKAPK_MK2_MAPKAPK2_ST	Q00613	HSF1	P49137	MAPKAPK2	S307	E312A	312	Missense	distal	5	no	12.426	12.374	EPSD	GDSC	11.681	Down-regulation
CAMK_MAPKAPK_MK2_MAPKAPK2_ST	Q00613	HSF1	P49137	MAPKAPK2	S314	E312A	312	Missense	proximal	-2	no	10.737	12.586	EPSD	GDSC	11.681	Gain
CAMK_MAPKAPK_MK2_MAPKAPK2_ST	Q00613	HSF1	P49137	MAPKAPK2	S338	V345I	345	Missense	distal	7	no	12.439	12.399	EPSD	GDSC	11.681	Down-regulation
CAMK_MAPKAPK_MK2_MAPKAPK2_ST	Q00613	HSF1	P49137	MAPKAPK2	T355	R360Q	360	Missense	distal	5	no	13.826	14.045	EPSD	GDSC	11.681	Up-regulation
CAMK_MAPKAPK_MK2_MAPKAPK2_ST	Q00613	HSF1	P49137	MAPKAPK2	T355	R360W	360	Missense	distal	5	no	13.826	14.046	EPSD	GDSC;CCLE	11.681	Up-regulation
CAMK_MAPKAPK_MK2_MAPKAPK2_ST	Q00613	HSF1	P49137	MAPKAPK2	S363	R360Q	360	Missense	distal	-3	no	18.111	12.347	EPSD	GDSC	11.681	Down-regulation
CAMK_MAPKAPK_MK2_MAPKAPK2_ST	Q00613	HSF1	P49137	MAPKAPK2	S363	R360W	360	Missense	distal	-3	no	18.111	9.532	EPSD	GDSC;CCLE	11.681	Loss
CAMK_MAPKAPK_MK2_MAPKAPK2_ST	Q00613	HSF1	P49137	MAPKAPK2	S458	S458I	458	Missense	central	0	yes	12.274	0.000	EPSD	GDSC;CCLE	11.681	Loss
CAMK_MAPKAPK_MK2_MAPKAPK2_ST	Q07817	BCL2L1	P49137	MAPKAPK2	S49	S43L	43	Missense	distal	-6	no	13.185	13.217	EPSD	GDSC;CCLE	11.681	Up-regulation
CAMK_MAPKAPK_MK2_MAPKAPK2_ST	Q07817	BCL2L1	P49137	MAPKAPK2	S49	P55S	55	Missense	distal	6	no	13.185	13.202	EPSD	GDSC;CCLE	11.681	Up-regulation
CAMK_MAPKAPK_MK2_MAPKAPK2_ST	Q07817	BCL2L1	P49137	MAPKAPK2	S62	P55S	55	Missense	distal	-7	no	12.896	12.899	PhosphoSitePlus	GDSC;CCLE	11.681	Up-regulation
CAMK_MAPKAPK_MK2_MAPKAPK2_ST	Q07817	BCL2L1	P49137	MAPKAPK2	S62	T69I	69	Missense	distal	7	no	12.896	12.331	PhosphoSitePlus	GDSC;CCLE	11.681	Down-regulation
CAMK_MAPKAPK_MK2_MAPKAPK2_ST	Q07817	BCL2L1	P49137	MAPKAPK2	S62	G67V	67	Missense	distal	5	no	12.896	12.790	PhosphoSitePlus	GDSC;CCLE	11.681	Down-regulation
CAMK_MAPKAPK_MK2_MAPKAPK2_ST	Q16875	PFKFB3	P49137	MAPKAPK2	S478	R475H	475	Missense	distal	-3	no	15.214	10.455	EPSD	GDSC;CCLE	11.681	Loss
CAMK_MAPKAPK_MK2_MAPKAPK2_ST	P49815	TSC2	P49137	MAPKAPK2	S609	A614T	614	Missense	distal	5	no	12.074	11.992	EPSD	GDSC	11.681	Down-regulation
CAMK_MAPKAPK_MK2_MAPKAPK2_ST	P49815	TSC2	P49137	MAPKAPK2	S609	I606V	606	Missense	distal	-3	no	12.074	9.635	EPSD	GDSC;CCLE	11.681	Loss
CAMK_MAPKAPK_MK2_MAPKAPK2_ST	P49815	TSC2	P49137	MAPKAPK2	S981	R988C	988	Missense	distal	7	no	21.035	20.782	EPSD	GDSC;CCLE	11.681	Down-regulation
CAMK_MAPKAPK_MK2_MAPKAPK2_ST	P49815	TSC2	P49137	MAPKAPK2	S983	R988C	988	Missense	distal	5	no	12.332	12.558	EPSD	GDSC;CCLE	11.681	Up-regulation
CAMK_MAPKAPK_MK2_MAPKAPK2_ST	P49815	TSC2	P49137	MAPKAPK2	S1045	P1042R	1042	Missense	distal	-3	no	9.054	13.719	EPSD	GDSC;CCLE	11.681	Gain
CAMK_MAPKAPK_MK2_MAPKAPK2_ST	P49815	TSC2	P49137	MAPKAPK2	S1155	R1159W	1159	Missense	distal	4	no	14.029	13.918	EPSD	GDSC	11.681	Down-regulation
CAMK_MAPKAPK_MK2_MAPKAPK2_ST	P49815	TSC2	P49137	MAPKAPK2	S1259	L1266M	1266	Missense	distal	7	no	12.844	13.056	EPSD	GDSC;CCLE	11.681	Up-regulation
CAMK_MAPKAPK_MK2_MAPKAPK2_ST	P49815	TSC2	P49137	MAPKAPK2	T1271	L1266M	1266	Missense	distal	-5	no	17.058	16.302	EPSD	GDSC;CCLE	11.681	Down-regulation
CAMK_MAPKAPK_MK2_MAPKAPK2_ST	P49815	TSC2	P49137	MAPKAPK2	S1418	S1411R	1411	Missense	distal	-7	no	12.237	12.203	EPSD	GDSC;CCLE	11.681	Down-regulation
CAMK_MAPKAPK_MK2_MAPKAPK2_ST	P49815	TSC2	P49137	MAPKAPK2	S1730	Y1736S	1736	Missense	distal	6	no	14.551	14.592	EPSD	GDSC	11.681	Up-regulation
CAMK_MAPKAPK_MK2_MAPKAPK2_ST	P30307	CDC25C	P49137	MAPKAPK2	S38	E34Q	34	Missense	distal	-4	no	14.586	14.699	EPSD	GDSC;CCLE	11.681	Up-regulation
CAMK_MAPKAPK_MK2_MAPKAPK2_ST	P30307	CDC25C	P49137	MAPKAPK2	S451	R458Q	458	Missense	distal	7	no	18.092	17.729	EPSD	GDSC;CCLE	11.681	Down-regulation
CAMK_MAPKAPK_MK2_MAPKAPK2_ST	P35900	KRT20	P49137	MAPKAPK2	T31	V24A	24	Missense	distal	-7	no	13.404	13.360	EPSD	GDSC;CCLE	11.681	Down-regulation
CAMK_MAPKAPK_MK2_MAPKAPK2_ST	P35900	KRT20	P49137	MAPKAPK2	S118	A119V	119	Missense	proximal	1	no	12.619	12.868	EPSD	GDSC;CCLE	11.681	Up-regulation
CAMK_CAMKL_MARK_MARK3_ST	P27448	MARK3	P27448-3	MARK3	S383	R388T	388	Missense	distal	5	no	295.051	295.881	EPSD	GDSC;CCLE	255.132	Up-regulation
CAMK_CAMKL_MARK_MARK3_ST	P27448	MARK3	P27448-3	MARK3	S390	R388T	388	Missense	proximal	-2	no	263.021	247.777	EPSD	GDSC;CCLE	255.132	Loss
CAMK_CAMKL_MARK_MARK3_ST	P27448	MARK3	P27448-3	MARK3	S390	S396I	396	Missense	distal	6	no	263.021	268.139	EPSD	GDSC;CCLE	255.132	Up-regulation
CAMK_CAMKL_MARK_MARK3_ST	P27448	MARK3	P27448-3	MARK3	S391	R388T	388	Missense	distal	-3	no	258.245	234.255	EPSD	GDSC;CCLE	255.132	Loss
CAMK_CAMKL_MARK_MARK3_ST	P27448	MARK3	P27448-3	MARK3	S391	S396I	396	Missense	distal	5	no	258.245	249.550	EPSD	GDSC;CCLE	255.132	Loss
CAMK_CAMKL_MARK_MARK3_ST	P27448	MARK3	P27448-3	MARK3	S499	R505*	505	Missense	distal	6	no	263.040	257.393	EPSD	GDSC	255.132	Down-regulation
CAMK_CAMKL_MARK_MARK3_ST	P27448	MARK3	P27448-3	MARK3	S499	S499A	499	Missense	central	0	yes	263.040	0.000	EPSD	GDSC;CCLE	255.132	Loss
CAMK_CAMKL_MARK_MARK3_ST	P27448	MARK3	P27448-3	MARK3	T576	P581L	581	Missense	distal	5	no	260.044	301.754	EPSD	GDSC;CCLE	255.132	Up-regulation
CAMK_CAMKL_MARK_MARK3_ST	P27448	MARK3	P27448-3	MARK3	T576	G579A	579	Missense	distal	3	no	260.044	258.494	EPSD	GDSC	255.132	Down-regulation
CAMK_CAMKL_MARK_MARK3_ST	P27448	MARK3	P27448-3	MARK3	T576	R572W	572	Missense	distal	-4	no	260.044	246.479	EPSD	GDSC;CCLE	255.132	Loss
CAMK_CAMKL_MARK_MARK3_ST	P27448	MARK3	P27448-3	MARK3	T591	R597*	597	Missense	distal	6	no	257.916	252.270	EPSD	GDSC	255.132	Loss
CAMK_CAMKL_MARK_MARK3_ST	P27448	MARK3	P27448-3	MARK3	S598	R597*	597	Missense	proximal	-1	no	498.268	499.017	EPSD;PhosphoSitePlus	GDSC	255.132	Up-regulation
CAMK_CAMKL_MARK_MARK3_ST	P27448	MARK3	P27448-3	MARK3	S601	R597*	597	Missense	distal	-4	no	377.882	361.754	PhosphoSitePlus;EPSD	GDSC	255.132	Down-regulation
CAMK_CAMKL_MARK_MARK3_ST	P27448	MARK3	P27448-3	MARK3	T602	R597*	597	Missense	distal	-5	no	369.966	353.140	EPSD;PhosphoSitePlus	GDSC	255.132	Down-regulation
CAMK_CAMKL_MARK_MARK3_ST	P27448	MARK3	P27448-3	MARK3	T627	E630D	630	Missense	distal	3	no	339.169	339.139	EPSD	GDSC;CCLE	255.132	Down-regulation
CAMK_CAMKL_MARK_MARK3_ST	P27448	MARK3	P27448-3	MARK3	T627	I622M	622	Missense	distal	-5	no	339.169	399.326	EPSD	GDSC;CCLE	255.132	Up-regulation
CAMK_CAMKL_MARK_MARK3_ST	P27448	MARK3	P27448-3	MARK3	S663	S663I	663	Missense	central	0	yes	360.773	0.000	EPSD	GDSC;CCLE	255.132	Loss
CAMK_CAMKL_MARK_MARK3_ST	P27448	MARK3	P27448-3	MARK3	S668	S663I	663	Missense	distal	-5	no	261.915	274.649	EPSD	GDSC;CCLE	255.132	Up-regulation
CAMK_CAMKL_MARK_MARK3_ST	P27448	MARK3	P27448-3	MARK3	S669	S663I	663	Missense	distal	-6	no	418.837	418.371	EPSD	GDSC;CCLE	255.132	Down-regulation
CK1_CK1_CK1-G_CSNK1G2_ST	Q14457	BECN1	P78368	CSNK1G2	S7	Q13*	13	Missense	distal	6	no	1.776	1.753	EPSD	GDSC	1.578	Down-regulation
CK1_CK1_CK1-G_CSNK1G2_ST	Q14457	BECN1	P78368	CSNK1G2	S7	S10N	10	Missense	distal	3	no	1.776	0.479	EPSD	GDSC;CCLE	1.578	Loss
CK1_CK1_CK1-G_CSNK1G2_ST	Q14457	BECN1	P78368	CSNK1G2	T11	Q13*	13	Missense	proximal	2	no	2.345	2.367	EPSD	GDSC	1.578	Up-regulation
CK1_CK1_CK1-G_CSNK1G2_ST	Q14457	BECN1	P78368	CSNK1G2	T11	S10N	10	Missense	proximal	-1	no	2.345	2.549	EPSD	GDSC;CCLE	1.578	Up-regulation
CK1_CK1_CK1-G_CSNK1G2_ST	O14654	IRS4	P78368	CSNK1G2	S558	A553T	553	Missense	distal	-5	no	1.678	1.619	EPSD	GDSC;CCLE	1.578	Down-regulation
CK1_CK1_CK1-G_CSNK1G2_ST	O14654	IRS4	P78368	CSNK1G2	T643	G650A	650	Missense	distal	7	no	3.133	3.105	EPSD	GDSC;CCLE	1.578	Down-regulation
CK1_CK1_CK1-G_CSNK1G2_ST	O14654	IRS4	P78368	CSNK1G2	T709	A708V	708	Missense	proximal	-1	no	2.376	2.373	EPSD	GDSC;CCLE	1.578	Down-regulation
CK1_CK1_CK1-G_CSNK1G2_ST	O14654	IRS4	P78368	CSNK1G2	S770	N765D	765	Missense	distal	-5	no	2.537	2.215	EPSD	GDSC;CCLE	1.578	Down-regulation
CK1_CK1_CK1-G_CSNK1G2_ST	O14654	IRS4	P78368	CSNK1G2	S770	E767D	767	Missense	distal	-3	no	2.537	2.517	EPSD	GDSC	1.578	Down-regulation
CK1_CK1_CK1-G_CSNK1G2_ST	O14654	IRS4	P78368	CSNK1G2	S1063	P1069S	1069	Missense	distal	6	no	1.472	1.587	EPSD	GDSC	1.578	Gain
AGC_PKC_PKCd_PRKCQ_ST	P35241	RDX	Q04759	PRKCQ	T564	K563N	563	Missense	proximal	-1	no	1.468	1.462	PhosphoSitePlus	GDSC;CCLE	1.204	Down-regulation
AGC_PKC_PKCd_PRKCQ_ST	O15530	PDPK1	Q04759	PRKCQ	S410	G403D	403	Missense	distal	-7	no	1.791	1.792	EPSD	GDSC;CCLE	1.204	Up-regulation
AGC_PKC_PKCd_PRKCQ_ST	Q92934	BAD	Q04759	PRKCQ	S134	T137K	137	Missense	distal	3	no	1.741	1.756	EPSD	GDSC	1.204	Up-regulation
AGC_PKC_PKCd_PRKCQ_ST	Q92934	BAD	Q04759	PRKCQ	S134	L129F	129	Missense	distal	-5	no	1.741	1.795	EPSD	GDSC	1.204	Up-regulation
AGC_PKC_PKCd_PRKCQ_ST	Q92934	BAD	Q04759	PRKCQ	S144	F151L	151	Missense	distal	7	no	1.214	1.227	EPSD	GDSC;CCLE	1.204	Up-regulation
AGC_PKC_PKCd_PRKCQ_ST	Q92934	BAD	Q04759	PRKCQ	S144	T137K	137	Missense	distal	-7	no	1.214	1.200	EPSD	GDSC	1.204	Loss
AGC_PKC_PKCd_PRKCQ_ST	Q92934	BAD	Q04759	PRKCQ	S145	F151L	151	Missense	distal	6	no	2.381	2.373	EPSD	GDSC;CCLE	1.204	Down-regulation
AGC_PKC_PKCd_PRKCQ_ST	Q04759	PRKCQ	Q04759	PRKCQ	S657	F651L	651	Missense	distal	-6	no	1.776	1.820	EPSD	GDSC;CCLE	1.204	Up-regulation
AGC_PKC_PKCd_PRKCQ_ST	Q04759	PRKCQ	Q04759	PRKCQ	S676	R680I	680	Missense	distal	4	no	2.038	1.867	EPSD	GDSC;CCLE	1.204	Down-regulation
AGC_PKC_PKCd_PRKCQ_ST	Q04759	PRKCQ	Q04759	PRKCQ	S695	N698S	698	Missense	distal	3	no	1.753	1.759	EPSD	GDSC;CCLE	1.204	Up-regulation
AGC_PKC_PKCd_PRKCQ_ST	Q04759	PRKCQ	Q04759	PRKCQ	S706	R703Q	703	Missense	distal	-3	no	1.770	0.542	EPSD	GDSC;CCLE	1.204	Loss
AGC_PKC_PKCd_PRKCQ_ST	P35568	IRS1	Q04759	PRKCQ	S24	H26R	26	Missense	proximal	2	no	1.549	1.775	EPSD	GDSC;CCLE	1.204	Up-regulation
AGC_PKC_PKCd_PRKCQ_ST	P35568	IRS1	Q04759	PRKCQ	S268	R267C	267	Missense	proximal	-1	no	1.946	1.934	EPSD	GDSC;CCLE	1.204	Down-regulation
AGC_PKC_PKCd_PRKCQ_ST	P35568	IRS1	Q04759	PRKCQ	S270	R267C	267	Missense	distal	-3	no	2.580	1.281	EPSD	GDSC;CCLE	1.204	Down-regulation
AGC_PKC_PKCd_PRKCQ_ST	P35568	IRS1	Q04759	PRKCQ	S272	R267C	267	Missense	distal	-5	no	1.399	1.137	EPSD	GDSC;CCLE	1.204	Loss
AGC_PKC_PKCd_PRKCQ_ST	P35568	IRS1	Q04759	PRKCQ	S362	R364W	364	Missense	proximal	2	no	1.815	1.551	EPSD	GDSC	1.204	Down-regulation
AGC_PKC_PKCd_PRKCQ_ST	P35568	IRS1	Q04759	PRKCQ	S362	P368A	368	Missense	distal	6	no	1.815	1.813	EPSD	GDSC;CCLE	1.204	Down-regulation
AGC_PKC_PKCd_PRKCQ_ST	P35568	IRS1	Q04759	PRKCQ	S374	H371R	371	Missense	distal	-3	no	0.221	1.334	EPSD	GDSC	1.204	Gain
AGC_PKC_PKCd_PRKCQ_ST	P35568	IRS1	Q04759	PRKCQ	S383	R381C	381	Missense	proximal	-2	no	1.259	0.555	EPSD	GDSC;CCLE	1.204	Loss
AGC_PKC_PKCd_PRKCQ_ST	P35568	IRS1	Q04759	PRKCQ	S383	A386S	386	Missense	distal	3	no	1.259	1.262	EPSD	GDSC;CCLE	1.204	Up-regulation
AGC_PKC_PKCd_PRKCQ_ST	P35568	IRS1	Q04759	PRKCQ	S383	P376L	376	Missense	distal	-7	no	1.259	1.266	EPSD	GDSC;CCLE	1.204	Up-regulation
AGC_PKC_PKCd_PRKCQ_ST	P35568	IRS1	Q04759	PRKCQ	S412	R411*	411	Missense	proximal	-1	no	1.494	1.481	EPSD	GDSC	1.204	Down-regulation
AGC_PKC_PKCd_PRKCQ_ST	P35568	IRS1	Q04759	PRKCQ	S413	R411*	411	Missense	proximal	-2	no	2.138	1.420	EPSD	GDSC	1.204	Down-regulation
AGC_PKC_PKCd_PRKCQ_ST	P35568	IRS1	Q04759	PRKCQ	S603	G597E	597	Missense	distal	-6	no	2.139	2.148	EPSD	GDSC	1.204	Up-regulation
AGC_PKC_PKCd_PRKCQ_ST	P35568	IRS1	Q04759	PRKCQ	S641	A642S	642	Missense	proximal	1	no	1.435	1.433	EPSD	GDSC;CCLE	1.204	Down-regulation
AGC_PKC_PKCd_PRKCQ_ST	P35568	IRS1	Q04759	PRKCQ	S869	L871F	871	Missense	proximal	2	no	1.781	1.835	EPSD	GDSC;CCLE	1.204	Up-regulation
AGC_PKC_PKCd_PRKCQ_ST	P35568	IRS1	Q04759	PRKCQ	S1084	S1084R	1084	Missense	central	0	yes	1.829	0.000	EPSD	GDSC	1.204	Loss
AGC_PKC_PKCd_PRKCQ_ST	P35568	IRS1	Q04759	PRKCQ	S1084	A1085D	1085	Missense	proximal	1	no	1.829	1.821	EPSD	GDSC;CCLE	1.204	Down-regulation
AGC_PKC_PKCd_PRKCQ_ST	P35568	IRS1	Q04759	PRKCQ	S1084	R1089G	1089	Missense	distal	5	no	1.829	1.798	EPSD	GDSC;CCLE	1.204	Down-regulation
AGC_PKC_PKCd_PRKCQ_ST	P35568	IRS1	Q04759	PRKCQ	S1100	R1096G	1096	Missense	distal	-4	no	2.727	2.668	EPSD	GDSC;CCLE	1.204	Down-regulation
AGC_PKC_PKCd_PRKCQ_ST	P35568	IRS1	Q04759	PRKCQ	S1101	R1096G	1096	Missense	distal	-5	no	2.483	2.214	PhosphoSitePlus	GDSC;CCLE	1.204	Down-regulation
AGC_PKC_PKCd_PRKCQ_ST	P35568	IRS1	Q04759	PRKCQ	S1222	S1218P	1218	Missense	distal	-4	no	1.283	1.276	EPSD	GDSC	1.204	Down-regulation
AGC_PKC_PKCd_PRKCQ_ST	P35568	IRS1	Q04759	PRKCQ	S1223	S1218P	1218	Missense	distal	-5	no	2.309	2.307	EPSD	GDSC	1.204	Down-regulation
AGC_PKC_PKCd_PRKCQ_ST	Q3V6T2	CCDC88A	Q04759	PRKCQ	S1702	L1706V	1706	Missense	distal	4	no	1.507	1.490	EPSD	GDSC	1.204	Down-regulation
AGC_PKC_PKCd_PRKCQ_ST	O95267	RASGRP1	Q04759	PRKCQ	T184	R177H	177	Missense	distal	-7	no	1.751	1.771	PhosphoSitePlus	GDSC	1.204	Up-regulation
AGC_PKC_PKCd_PRKCQ_ST	Q9BXL7	CARD11	Q04759	PRKCQ	S520	Q523E	523	Missense	distal	3	no	2.190	2.185	EPSD	GDSC;CCLE	1.204	Down-regulation
AGC_PKC_PKCd_PRKCQ_ST	Q9BXL7	CARD11	Q04759	PRKCQ	S558	R557H	557	Missense	proximal	-1	no	2.001	1.991	EPSD	GDSC	1.204	Down-regulation
AGC_PKC_PKCd_PRKCQ_ST	Q9BXL7	CARD11	Q04759	PRKCQ	S559	R557H	557	Missense	proximal	-2	no	1.890	1.287	PhosphoSitePlus	GDSC	1.204	Down-regulation
AGC_PKC_PKCd_PRKCQ_ST	Q9BXL7	CARD11	Q04759	PRKCQ	S619	H617R	617	Missense	proximal	-2	no	0.648	1.251	EPSD	GDSC;CCLE	1.204	Gain
AGC_PKC_PKCd_PRKCQ_ST	Q9BXL7	CARD11	Q04759	PRKCQ	S620	H617R	617	Missense	distal	-3	no	0.803	1.916	EPSD	GDSC;CCLE	1.204	Gain
AGC_PKC_PKCd_PRKCQ_ST	Q9BXL7	CARD11	Q04759	PRKCQ	S644	K642N	642	Missense	proximal	-2	no	2.782	2.366	EPSD	GDSC;CCLE	1.204	Down-regulation
AGC_PKC_PKCd_PRKCQ_ST	Q9BXL7	CARD11	Q04759	PRKCQ	S652	H658Q	658	Missense	distal	6	no	1.778	1.780	EPSD	GDSC;CCLE	1.204	Up-regulation
AGC_PKC_PKCd_PRKCQ_ST	Q9BXL7	CARD11	Q04759	PRKCQ	S886	D882V	882	Missense	distal	-4	no	1.869	1.863	EPSD	GDSC;CCLE	1.204	Down-regulation
AGC_PKC_PKCd_PRKCQ_ST	Q9BXL7	CARD11	Q04759	PRKCQ	S923	G928R	928	Missense	distal	5	no	2.375	2.406	EPSD	GDSC	1.204	Up-regulation
AGC_PKC_PKCd_PRKCQ_ST	Q9BXL7	CARD11	Q04759	PRKCQ	S923	S923L	923	Missense	central	0	yes	2.375	0.000	EPSD	GDSC;CCLE	1.204	Loss
AGC_PKC_PKCd_PRKCQ_ST	P01116	KRAS	Q04759	PRKCQ	S172	I171M	171	Missense	proximal	-1	no	2.221	2.223	EPSD	GDSC;CCLE	1.204	Up-regulation
AGC_PKC_PKCd_PRKCQ_ST	P15407	FOSL1	Q04759	PRKCQ	S251	S246*	246	Missense	distal	-5	no	1.542	1.456	EPSD	GDSC	1.204	Down-regulation
AGC_PKC_PKCd_PRKCQ_ST	P15407	FOSL1	Q04759	PRKCQ	S252	S246*	246	Missense	distal	-6	no	2.235	2.328	EPSD	GDSC	1.204	Up-regulation
AGC_PKC_PKCd_PRKCQ_ST	P15407	FOSL1	Q04759	PRKCQ	S253	S246*	246	Missense	distal	-7	no	1.518	1.524	EPSD	GDSC	1.204	Up-regulation
AGC_PKC_PKCd_PRKCQ_ST	P26038	MSN	Q04759	PRKCQ	S6	V9M	9	Missense	distal	3	no	1.727	1.735	EPSD	GDSC;CCLE	1.204	Up-regulation
AGC_PKC_PKCd_PRKCQ_ST	P26038	MSN	Q04759	PRKCQ	S74	V70L	70	Missense	distal	-4	no	2.000	2.005	EPSD	GDSC	1.204	Up-regulation
AGC_PKC_PKCd_PRKCQ_ST	P26038	MSN	Q04759	PRKCQ	S214	L218M	218	Missense	distal	4	no	2.190	2.222	EPSD	GDSC;CCLE	1.204	Up-regulation
AGC_PKC_PKCd_PRKCQ_ST	P26038	MSN	Q04759	PRKCQ	S440	R435*	435	Missense	distal	-5	no	1.649	1.373	EPSD	GDSC	1.204	Down-regulation
AGC_PKC_PKCd_PRKCQ_ST	O43516	WIPF1	Q04759	PRKCQ	S137	P130L	130	Missense	distal	-7	no	2.250	2.257	EPSD	GDSC;CCLE	1.204	Up-regulation
AGC_PKC_PKCd_PRKCQ_ST	O43516	WIPF1	Q04759	PRKCQ	S203	P204L	204	Missense	proximal	1	no	1.566	1.562	EPSD	GDSC;CCLE	1.204	Down-regulation
AGC_PKC_PKCd_PRKCQ_ST	O43516	WIPF1	Q04759	PRKCQ	S214	P217L	217	Missense	distal	3	no	1.518	1.512	EPSD	GDSC	1.204	Down-regulation
AGC_PKC_PKCd_PRKCQ_ST	O43516	WIPF1	Q04759	PRKCQ	S340	Q336*	336	Missense	distal	-4	no	1.634	1.617	EPSD	GDSC	1.204	Down-regulation
AGC_PKC_PKCd_PRKCQ_ST	O43516	WIPF1	Q04759	PRKCQ	S390	N388T	388	Missense	proximal	-2	no	1.714	1.688	EPSD	GDSC	1.204	Down-regulation
AGC_PKC_PKCd_PRKCQ_ST	O43516	WIPF1	Q04759	PRKCQ	S424	S424G	424	Missense	central	0	yes	1.282	0.000	EPSD	GDSC;CCLE	1.204	Loss
AGC_PKC_PKCd_PRKCQ_ST	O43516	WIPF1	Q04759	PRKCQ	S488	E492G	492	Missense	distal	4	no	2.044	2.047	PhosphoSitePlus	GDSC;CCLE	1.204	Up-regulation
AGC_PKC_PKCd_PRKCQ_ST	Q9Y4G8	RAPGEF2	Q04759	PRKCQ	S478	E472Q	472	Missense	distal	-6	no	1.434	1.383	EPSD	GDSC;CCLE	1.204	Down-regulation
AGC_PKC_PKCd_PRKCQ_ST	Q9Y4G8	RAPGEF2	Q04759	PRKCQ	S1153	S1152F	1152	Missense	proximal	-1	no	1.545	1.542	EPSD	GDSC;CCLE	1.204	Down-regulation
AGC_PKC_PKCd_PRKCQ_ST	Q13191	CBLB	Q04759	PRKCQ	T471	R468*	468	Missense	distal	-3	no	1.691	0.403	EPSD	GDSC	1.204	Loss
AGC_PKC_PKCd_PRKCQ_ST	Q13191	CBLB	Q04759	PRKCQ	T471	N466K	466	Missense	distal	-5	no	1.691	1.855	EPSD	GDSC;CCLE	1.204	Up-regulation
AGC_PKC_PKCd_PRKCQ_ST	Q13191	CBLB	Q04759	PRKCQ	S476	T479A	479	Missense	distal	3	no	1.610	1.617	EPSD	GDSC;CCLE	1.204	Up-regulation
AGC_PKC_PKCd_PRKCQ_ST	Q13191	CBLB	Q04759	PRKCQ	S533	C535G	535	Missense	proximal	2	no	1.241	1.226	EPSD	GDSC;CCLE	1.204	Down-regulation
AGC_PKC_PKCd_PRKCQ_ST	Q13191	CBLB	Q04759	PRKCQ	S580	H577R	577	Missense	distal	-3	no	0.807	1.920	EPSD	GDSC;CCLE	1.204	Gain
AGC_PKC_PKCd_PRKCQ_ST	Q13191	CBLB	Q04759	PRKCQ	S634	L638F	638	Missense	distal	4	no	1.742	1.773	EPSD	GDSC;CCLE	1.204	Up-regulation
AGC_PKC_PKCd_PRKCQ_ST	Q13191	CBLB	Q04759	PRKCQ	S672	R670Q	670	Missense	proximal	-2	no	1.394	0.738	EPSD	GDSC	1.204	Loss
AGC_PKC_PKCd_PRKCQ_ST	Q13191	CBLB	Q04759	PRKCQ	S793	H791Y	791	Missense	proximal	-2	no	1.494	1.447	EPSD	GDSC;CCLE	1.204	Down-regulation
AGC_PKC_PKCd_PRKCQ_ST	Q13191	CBLB	Q04759	PRKCQ	S886	N883D	883	Missense	distal	-3	no	1.420	1.200	EPSD	GDSC	1.204	Loss
AGC_PKC_PKCd_PRKCQ_ST	Q13191	CBLB	Q04759	PRKCQ	S977	L980I	980	Missense	distal	3	no	1.450	1.451	EPSD	GDSC;CCLE	1.204	Up-regulation
AGC_PKC_PKCd_PRKCQ_ST	Q5JVS0	HABP4	Q04759	PRKCQ	T375	R376Q	376	Missense	proximal	1	no	1.246	1.230	PhosphoSitePlus;EPSD	GDSC;CCLE	1.204	Down-regulation
AGC_PKC_PKCd_PRKCQ_ST	O14974	PPP1R12A	Q04759	PRKCQ	S541	K538*	538	Missense	distal	-3	no	2.101	1.230	EPSD	GDSC	1.204	Down-regulation
AGC_PKC_PKCd_PRKCQ_ST	O14974	PPP1R12A	Q04759	PRKCQ	S541	E545K	545	Missense	distal	4	no	2.101	2.224	EPSD	GDSC;CCLE	1.204	Up-regulation
AGC_PKC_PKCd_PRKCQ_ST	O14974	PPP1R12A	Q04759	PRKCQ	S542	K538*	538	Missense	distal	-4	no	1.712	1.673	EPSD	GDSC	1.204	Down-regulation
AGC_PKC_PKCd_PRKCQ_ST	O14974	PPP1R12A	Q04759	PRKCQ	S542	E545K	545	Missense	distal	3	no	1.712	1.726	EPSD	GDSC;CCLE	1.204	Up-regulation
AGC_PKC_PKCd_PRKCQ_ST	O14974	PPP1R12A	Q04759	PRKCQ	S716	R720T	720	Missense	distal	4	no	2.440	2.268	EPSD	GDSC;CCLE	1.204	Down-regulation
AGC_PKC_PKCd_PRKCQ_ST	O14974	PPP1R12A	Q04759	PRKCQ	S716	R715L	715	Missense	proximal	-1	no	2.440	2.427	EPSD	GDSC;CCLE	1.204	Down-regulation
AGC_PKC_PKCd_PRKCQ_ST	O14974	PPP1R12A	Q04759	PRKCQ	S903	R900*	900	Missense	distal	-3	no	1.716	0.428	EPSD	GDSC	1.204	Loss
AGC_PKC_PKCd_PRKCQ_ST	O14974	PPP1R12A	Q04759	PRKCQ	S995	R993K	993	Missense	proximal	-2	no	2.086	1.843	EPSD	GDSC;CCLE	1.204	Down-regulation
AGC_PKC_PKCd_PRKCQ_ST	Q15052	ARHGEF6	Q04759	PRKCQ	S124	R121H	121	Missense	distal	-3	no	1.795	0.682	EPSD	GDSC	1.204	Loss
AGC_PKC_PKCd_PRKCQ_ST	Q15052	ARHGEF6	Q04759	PRKCQ	S150	T152I	152	Missense	proximal	2	no	1.234	1.229	EPSD	GDSC;CCLE	1.204	Down-regulation
AGC_PKC_PKCd_PRKCQ_ST	Q15052	ARHGEF6	Q04759	PRKCQ	S225	V229I	229	Missense	distal	4	no	2.148	2.172	PhosphoSitePlus;EPSD	GDSC	1.204	Up-regulation
AGC_PKC_PKCd_PRKCQ_ST	Q15052	ARHGEF6	Q04759	PRKCQ	S488	R486Q	486	Missense	proximal	-2	no	1.525	0.869	EPSD;PhosphoSitePlus	GDSC;CCLE	1.204	Loss
AGC_PKC_PKCd_PRKCQ_ST	Q15052	ARHGEF6	Q04759	PRKCQ	S620	L616S	616	Missense	distal	-4	no	1.272	1.297	EPSD	GDSC;CCLE	1.204	Up-regulation
AGC_PKC_PKCd_PRKCQ_ST	Q15052	ARHGEF6	Q04759	PRKCQ	S640	E643*	643	Missense	distal	3	no	1.823	1.820	EPSD	GDSC	1.204	Down-regulation
AGC_PKC_PKCd_PRKCQ_ST	Q15052	ARHGEF6	Q04759	PRKCQ	S649	E643*	643	Missense	distal	-6	no	1.243	1.252	EPSD	GDSC	1.204	Up-regulation
AGC_PKC_PKCd_PRKCQ_ST	Q15052	ARHGEF6	Q04759	PRKCQ	S649	A652V	652	Missense	distal	3	no	1.243	1.235	EPSD	GDSC;CCLE	1.204	Down-regulation
AGC_PKC_PKCd_PRKCQ_ST	Q15052	ARHGEF6	Q04759	PRKCQ	S684	P686T	686	Missense	proximal	2	no	2.236	2.172	EPSD	GDSC;CCLE	1.204	Down-regulation
AGC_PKC_PKCd_PRKCQ_ST	Q8IV61	RASGRP3	Q04759	PRKCQ	T133	K140*	140	Missense	distal	7	no	2.341	2.408	PhosphoSitePlus	GDSC	1.204	Up-regulation
AGC_PKC_PKCd_PRKCQ_ST	Q8IV61	RASGRP3	Q04759	PRKCQ	S385	S387*	387	Missense	proximal	2	no	1.489	1.456	EPSD	GDSC	1.204	Down-regulation
AGC_PKC_PKCd_PRKCQ_ST	Q8IV61	RASGRP3	Q04759	PRKCQ	S552	A548T	548	Missense	distal	-4	no	1.608	1.588	EPSD	GDSC;CCLE	1.204	Down-regulation
AGC_PKC_PKCd_PRKCQ_ST	Q8IV61	RASGRP3	Q04759	PRKCQ	S552	G558A	558	Missense	distal	6	no	1.608	1.623	EPSD	GDSC;CCLE	1.204	Up-regulation
AGC_PKA_PRKACB_ST	Q01130	SRSF2	P22694	PRKACB	S128	R133W	133	Missense	distal	5	no	2.373	2.374	EPSD;PhosphoSitePlus	GDSC;CCLE	2.323	Up-regulation
AGC_PKA_PRKACB_ST	Q01130	SRSF2	P22694	PRKACB	S130	R133W	133	Missense	distal	3	no	2.496	2.451	EPSD;PhosphoSitePlus	GDSC;CCLE	2.323	Down-regulation
AGC_PKA_PRKACB_ST	Q01130	SRSF2	P22694	PRKACB	S134	R133W	133	Missense	proximal	-1	no	2.934	2.957	EPSD	GDSC;CCLE	2.323	Up-regulation
AGC_PKA_PRKACB_ST	Q01130	SRSF2	P22694	PRKACB	S136	R133W	133	Missense	distal	-3	no	3.388	1.287	EPSD	GDSC;CCLE	2.323	Loss
CK1_CK1_CK1-G_CSNK1G1_ST	P25054	APC	Q9HCP0	CSNK1G1	S95	S98I	98	Missense	distal	3	no	2.401	2.239	EPSD	GDSC;CCLE	1.928	Down-regulation
CK1_CK1_CK1-G_CSNK1G1_ST	P25054	APC	Q9HCP0	CSNK1G1	S98	S98I	98	Missense	central	0	yes	2.046	0.000	EPSD	GDSC;CCLE	1.928	Loss
CK1_CK1_CK1-G_CSNK1G1_ST	P25054	APC	Q9HCP0	CSNK1G1	S299	R302*	302	Missense	distal	3	no	1.952	1.929	EPSD	GDSC	1.928	Down-regulation
CK1_CK1_CK1-G_CSNK1G1_ST	P25054	APC	Q9HCP0	CSNK1G1	S559	R564*	564	Missense	distal	5	no	2.048	2.050	EPSD	GDSC	1.928	Up-regulation
CK1_CK1_CK1-G_CSNK1G1_ST	P25054	APC	Q9HCP0	CSNK1G1	S874	R876*	876	Missense	proximal	2	no	2.555	2.552	EPSD	GDSC	1.928	Down-regulation
CK1_CK1_CK1-G_CSNK1G1_ST	P25054	APC	Q9HCP0	CSNK1G1	S1180	K1182*	1182	Missense	proximal	2	no	2.050	2.039	EPSD	GDSC	1.928	Down-regulation
CK1_CK1_CK1-G_CSNK1G1_ST	P25054	APC	Q9HCP0	CSNK1G1	S1371	Q1367*	1367	Missense	distal	-4	no	1.970	1.977	EPSD	GDSC	1.928	Up-regulation
CK1_CK1_CK1-G_CSNK1G1_ST	P25054	APC	Q9HCP0	CSNK1G1	S1504	G1499*	1499	Missense	distal	-5	no	5.966	6.001	EPSD;PhosphoSitePlus	GDSC	1.928	Up-regulation
CK1_CK1_CK1-G_CSNK1G1_ST	P25054	APC	Q9HCP0	CSNK1G1	S1505	G1499*	1499	Missense	distal	-6	no	5.317	4.981	EPSD;PhosphoSitePlus	GDSC	1.928	Down-regulation
CK1_CK1_CK1-G_CSNK1G1_ST	P25054	APC	Q9HCP0	CSNK1G1	S1507	E1513*	1513	Missense	distal	6	no	5.668	5.518	PhosphoSitePlus;EPSD	GDSC	1.928	Down-regulation
CK1_CK1_CK1-G_CSNK1G1_ST	P25054	APC	Q9HCP0	CSNK1G1	S1510	E1513*	1513	Missense	distal	3	no	5.287	5.293	EPSD;PhosphoSitePlus	GDSC	1.928	Up-regulation
CK1_CK1_CK1-G_CSNK1G1_ST	P25054	APC	Q9HCP0	CSNK1G1	S2034	S2028T	2028	Missense	distal	-6	no	2.197	1.641	EPSD	GDSC;CCLE	1.928	Loss
CK1_CK1_CK1-G_CSNK1G1_ST	P25054	APC	Q9HCP0	CSNK1G1	S2146	G2145V	2145	Missense	proximal	-1	no	2.097	2.047	EPSD	GDSC;CCLE	1.928	Down-regulation
CK1_CK1_CK1-G_CSNK1G1_ST	P25054	APC	Q9HCP0	CSNK1G1	S2146	L2150V	2150	Missense	distal	4	no	2.097	2.016	EPSD	GDSC;CCLE	1.928	Down-regulation
CK1_CK1_CK1-G_CSNK1G1_ST	P25054	APC	Q9HCP0	CSNK1G1	T2269	S2262N	2262	Missense	distal	-7	no	1.982	1.819	EPSD	GDSC;CCLE	1.928	Loss
CK1_CK1_CK1-G_CSNK1G1_ST	P25054	APC	Q9HCP0	CSNK1G1	S2349	L2342F	2342	Missense	distal	-7	no	1.975	1.873	EPSD	GDSC;CCLE	1.928	Loss
CK1_CK1_CK1-G_CSNK1G1_ST	P25054	APC	Q9HCP0	CSNK1G1	S2466	P2467L	2467	Missense	proximal	1	no	1.876	2.219	EPSD	GDSC;CCLE	1.928	Gain
CK1_CK1_CK1-G_CSNK1G1_ST	P25054	APC	Q9HCP0	CSNK1G1	S2468	F2462S	2462	Missense	distal	-6	no	1.333	2.251	EPSD	GDSC;CCLE	1.928	Gain
CK1_CK1_CK1-G_CSNK1G1_ST	P25054	APC	Q9HCP0	CSNK1G1	S2575	S2575Y	2575	Missense	central	0	yes	2.091	0.000	EPSD	GDSC	1.928	Loss
CK1_CK1_CK1-G_CSNK1G1_ST	P25054	APC	Q9HCP0	CSNK1G1	S2627	S2625I	2625	Missense	proximal	-2	no	2.082	2.061	EPSD	GDSC;CCLE	1.928	Down-regulation
CK1_CK1_CK1-G_CSNK1G1_ST	O75581	LRP6	Q9HCP0	CSNK1G1	S646	R644*	644	Missense	proximal	-2	no	2.084	2.082	EPSD	GDSC	1.928	Down-regulation
CK1_CK1_CK1-G_CSNK1G1_ST	O75581	LRP6	Q9HCP0	CSNK1G1	T1479	T1479I	1479	Missense	central	0	yes	5.577	0.000	PhosphoSitePlus	GDSC	1.928	Loss
CK1_CK1_CK1-G_CSNK1G1_ST	O75581	LRP6	Q9HCP0	CSNK1G1	S1496	R1495Q	1495	Missense	proximal	-1	no	1.912	1.935	EPSD	GDSC	1.928	Gain
CAMK_CAMKL_CHK1_CHEK1_ST	Q6PD62	CTR9	O14757	CHEK1	T263	D265N	265	Missense	proximal	2	no	12.864	12.580	EPSD	GDSC;CCLE	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q6PD62	CTR9	O14757	CHEK1	S941	K939N	939	Missense	proximal	-2	no	12.944	13.215	EPSD	GDSC	5.604	Up-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q6PD62	CTR9	O14757	CHEK1	S1081	D1086V	1086	Missense	distal	5	no	8.022	7.850	PhosphoSitePlus	GDSC;CCLE	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q6PD62	CTR9	O14757	CHEK1	S1081	D1082Y	1082	Missense	proximal	1	no	8.022	7.900	PhosphoSitePlus	GDSC;CCLE	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q6PD62	CTR9	O14757	CHEK1	S1114	G1115R	1115	Missense	proximal	1	no	8.649	8.657	EPSD	GDSC;CCLE	5.604	Up-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q6PD62	CTR9	O14757	CHEK1	S1125	S1130*	1130	Missense	distal	5	no	6.650	6.251	EPSD	GDSC	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	P11047	LAMC1	O14757	CHEK1	S1149	I1145V	1145	Missense	distal	-4	no	5.583	5.863	EPSD	GDSC;CCLE	5.604	Gain
CAMK_CAMKL_CHK1_CHEK1_ST	P11047	LAMC1	O14757	CHEK1	S1552	S1552I	1552	Missense	central	0	yes	6.723	0.000	EPSD	GDSC;CCLE	5.604	Loss
CAMK_CAMKL_CHK1_CHEK1_ST	P11047	LAMC1	O14757	CHEK1	S1559	S1552I	1552	Missense	distal	-7	no	14.923	14.280	EPSD	GDSC;CCLE	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q9NUU7	DDX19A	O14757	CHEK1	S92	P86S	86	Missense	distal	-6	no	7.232	7.134	PhosphoSitePlus	GDSC;CCLE	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	P22626	HNRNPA2B1	O14757	CHEK1	S231	G224*	224	Missense	distal	-7	no	7.700	5.895	EPSD	GDSC	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	P84098	RPL19	O14757	CHEK1	T29	N34S	34	Missense	distal	5	no	6.088	6.090	EPSD	GDSC	5.604	Up-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	P67809	YBX1	O14757	CHEK1	S176	E169A	169	Missense	distal	-7	no	6.877	7.103	EPSD	GDSC	5.604	Up-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	P67809	YBX1	O14757	CHEK1	T271	G268R	268	Missense	distal	-3	no	3.544	11.318	EPSD	GDSC	5.604	Gain
CAMK_CAMKL_CHK1_CHEK1_ST	Q7Z2Z1	TICRR	O14757	CHEK1	T207	V211M	211	Missense	distal	4	no	8.967	8.966	EPSD	GDSC	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q7Z2Z1	TICRR	O14757	CHEK1	S891	P893R	893	Missense	proximal	2	no	7.297	7.279	EPSD	GDSC	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q7Z2Z1	TICRR	O14757	CHEK1	S938	P934S	934	Missense	distal	-4	no	11.595	11.359	EPSD	GDSC	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q7Z2Z1	TICRR	O14757	CHEK1	S1026	A1027S	1027	Missense	proximal	1	no	8.434	8.416	EPSD	GDSC;CCLE	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q7Z2Z1	TICRR	O14757	CHEK1	S1057	P1058A	1058	Missense	proximal	1	no	9.076	9.130	EPSD	GDSC;CCLE	5.604	Up-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q7Z2Z1	TICRR	O14757	CHEK1	S1894	T1896N	1896	Missense	proximal	2	no	7.027	7.601	EPSD;PhosphoSitePlus	GDSC	5.604	Up-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q7Z2Z1	TICRR	O14757	CHEK1	S1894	K1901Q	1901	Missense	distal	7	no	7.027	7.107	EPSD;PhosphoSitePlus	GDSC	5.604	Up-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q7Z2Z1	TICRR	O14757	CHEK1	T1898	T1896N	1896	Missense	proximal	-2	no	9.472	9.407	PhosphoSitePlus;EPSD	GDSC	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q7Z2Z1	TICRR	O14757	CHEK1	T1898	K1901Q	1901	Missense	distal	3	no	9.472	9.887	PhosphoSitePlus;EPSD	GDSC	5.604	Up-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q9NRL2	BAZ1A	O14757	CHEK1	S601	Y606H	606	Missense	distal	5	no	7.837	8.204	EPSD	GDSC;CCLE	5.604	Up-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q9NRL2	BAZ1A	O14757	CHEK1	T771	D773N	773	Missense	proximal	2	no	6.558	6.273	EPSD	GDSC	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q9NRL2	BAZ1A	O14757	CHEK1	S960	Y964C	964	Missense	distal	4	no	9.431	9.411	EPSD	GDSC;CCLE	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q9NRL2	BAZ1A	O14757	CHEK1	S960	R957Q	957	Missense	distal	-3	no	9.431	2.224	EPSD	GDSC;CCLE	5.604	Loss
CAMK_CAMKL_CHK1_CHEK1_ST	Q9NRL2	BAZ1A	O14757	CHEK1	S1320	A1321V	1321	Missense	proximal	1	no	8.923	8.898	PhosphoSitePlus	GDSC;CCLE	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q9NRL2	BAZ1A	O14757	CHEK1	S1320	I1318V	1318	Missense	proximal	-2	no	8.923	8.986	PhosphoSitePlus	GDSC	5.604	Up-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q9NRL2	BAZ1A	O14757	CHEK1	S1540	V1542A	1542	Missense	proximal	2	no	6.375	6.938	EPSD	GDSC	5.604	Up-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	P54132	BLM	O14757	CHEK1	S42	K40E	40	Missense	proximal	-2	no	6.851	6.994	EPSD	GDSC	5.604	Up-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	P54132	BLM	O14757	CHEK1	S269	E265G	265	Missense	distal	-4	no	9.017	8.840	EPSD	GDSC;CCLE	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	P54132	BLM	O14757	CHEK1	S460	H457R	457	Missense	distal	-3	no	3.903	9.713	EPSD	GDSC;CCLE	5.604	Gain
CAMK_CAMKL_CHK1_CHEK1_ST	P54132	BLM	O14757	CHEK1	S539	E546D	546	Missense	distal	7	no	8.908	8.966	PhosphoSitePlus;EPSD	GDSC;CCLE	5.604	Up-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	P54132	BLM	O14757	CHEK1	S597	A603V	603	Missense	distal	6	no	5.636	5.524	EPSD	GDSC;CCLE	5.604	Loss
CAMK_CAMKL_CHK1_CHEK1_ST	P54132	BLM	O14757	CHEK1	S602	A603V	603	Missense	proximal	1	no	7.824	7.800	EPSD	GDSC;CCLE	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	P54132	BLM	O14757	CHEK1	S646	S648G	648	Missense	proximal	2	no	9.083	9.018	EPSD;PhosphoSitePlus	GDSC;CCLE	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	P54132	BLM	O14757	CHEK1	S646	K653T	653	Missense	distal	7	no	9.083	8.848	EPSD;PhosphoSitePlus	GDSC	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	P54132	BLM	O14757	CHEK1	S823	P822T	822	Missense	proximal	-1	no	6.061	5.819	EPSD	GDSC;CCLE	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	P54132	BLM	O14757	CHEK1	S1375	S1368A	1368	Missense	distal	-7	no	5.848	6.298	EPSD	GDSC	5.604	Up-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q14669	TRIP12	O14757	CHEK1	T54	K59Q	59	Missense	distal	5	no	8.431	8.383	EPSD	GDSC;CCLE	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q14669	TRIP12	O14757	CHEK1	T54	A52T	52	Missense	proximal	-2	no	8.431	8.570	EPSD	GDSC;CCLE	5.604	Up-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q14669	TRIP12	O14757	CHEK1	S85	A89T	89	Missense	distal	4	no	7.771	7.589	EPSD	GDSC;CCLE	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q14669	TRIP12	O14757	CHEK1	S312	K307N	307	Missense	distal	-5	no	7.808	6.914	EPSD	GDSC;CCLE	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q14669	TRIP12	O14757	CHEK1	S780	I778T	778	Missense	proximal	-2	no	8.069	8.195	EPSD	GDSC	5.604	Up-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q9UKI8	TLK1	O14757	CHEK1	S105	G102R	102	Missense	distal	-3	no	0.996	8.771	EPSD	GDSC;CCLE	5.604	Gain
CAMK_CAMKL_CHK1_CHEK1_ST	P49761	CLK3	O14757	CHEK1	S157	R154*	154	Missense	distal	-3	no	10.275	-36.672	PhosphoSitePlus	GDSC	5.604	Loss
CAMK_CAMKL_CHK1_CHEK1_ST	P49761	CLK3	O14757	CHEK1	S173	R172G	172	Missense	proximal	-1	no	8.724	8.742	EPSD	GDSC	5.604	Up-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	P49761	CLK3	O14757	CHEK1	S175	R172G	172	Missense	distal	-3	no	8.264	0.490	EPSD	GDSC	5.604	Loss
CAMK_CAMKL_CHK1_CHEK1_ST	P49761	CLK3	O14757	CHEK1	S186	R183*	183	Missense	distal	-3	no	13.199	-33.748	EPSD	GDSC	5.604	Loss
CAMK_CAMKL_CHK1_CHEK1_ST	P49761	CLK3	O14757	CHEK1	S243	R244Q	244	Missense	proximal	1	no	9.239	9.247	EPSD	GDSC	5.604	Up-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	P49761	CLK3	O14757	CHEK1	S265	R261H	261	Missense	distal	-4	no	10.395	10.198	EPSD	GDSC;CCLE	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	P49761	CLK3	O14757	CHEK1	S267	R261H	261	Missense	distal	-6	no	8.524	8.634	EPSD	GDSC;CCLE	5.604	Up-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	P49761	CLK3	O14757	CHEK1	S463	R465*	465	Missense	proximal	2	no	6.624	6.021	EPSD	GDSC	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	P85299	PRR5	O14757	CHEK1	S240	R239C	239	Missense	proximal	-1	no	12.950	12.985	PhosphoSitePlus	GDSC;CCLE	5.604	Up-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	P85299	PRR5	O14757	CHEK1	S240	R233H	233	Missense	distal	-7	no	12.950	12.891	PhosphoSitePlus	GDSC	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	P85299	PRR5	O14757	CHEK1	S240	R233C	233	Missense	distal	-7	no	12.950	12.222	PhosphoSitePlus	GDSC;CCLE	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	P04637	TP53	O14757	CHEK1	S37	Q38*	38	Missense	proximal	1	no	8.422	8.342	PhosphoSitePlus;EPSD	GDSC	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	P04637	TP53	O14757	CHEK1	S366	G360V	360	Missense	distal	-6	no	7.200	7.174	EPSD	GDSC;CCLE	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q12789	GTF3C1	O14757	CHEK1	S667	R673*	673	Missense	distal	6	no	13.699	14.384	PhosphoSitePlus	GDSC	5.604	Up-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q12789	GTF3C1	O14757	CHEK1	S695	D700N	700	Missense	distal	5	no	7.572	7.483	EPSD	GDSC;CCLE	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q12789	GTF3C1	O14757	CHEK1	S836	R842W	842	Missense	distal	6	no	7.266	7.732	EPSD	GDSC;CCLE	5.604	Up-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q12789	GTF3C1	O14757	CHEK1	S836	R838M	838	Missense	proximal	2	no	7.266	7.434	EPSD	GDSC;CCLE	5.604	Up-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q12789	GTF3C1	O14757	CHEK1	S845	R842W	842	Missense	distal	-3	no	6.410	-27.193	EPSD	GDSC;CCLE	5.604	Loss
CAMK_CAMKL_CHK1_CHEK1_ST	Q12789	GTF3C1	O14757	CHEK1	S845	R838M	838	Missense	distal	-7	no	6.410	6.269	EPSD	GDSC;CCLE	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q12789	GTF3C1	O14757	CHEK1	S1062	R1057C	1057	Missense	distal	-5	no	11.732	11.054	EPSD	GDSC;CCLE	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q12789	GTF3C1	O14757	CHEK1	S1063	R1057C	1057	Missense	distal	-6	no	7.279	7.395	EPSD	GDSC;CCLE	5.604	Up-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q12789	GTF3C1	O14757	CHEK1	S1641	A1638V	1638	Missense	distal	-3	no	6.862	5.110	EPSD	GDSC;CCLE	5.604	Loss
CAMK_CAMKL_CHK1_CHEK1_ST	Q12789	GTF3C1	O14757	CHEK1	S1865	T1860N	1860	Missense	distal	-5	no	10.048	9.409	EPSD	GDSC;CCLE	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q12789	GTF3C1	O14757	CHEK1	S1865	A1864T	1864	Missense	proximal	-1	no	10.048	9.919	EPSD	GDSC	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q5T8P6	RBM26	O14757	CHEK1	S176	S178T	178	Missense	proximal	2	no	8.076	7.685	EPSD	GDSC;CCLE	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q5T8P6	RBM26	O14757	CHEK1	S180	S178T	178	Missense	proximal	-2	no	10.411	10.665	EPSD	GDSC;CCLE	5.604	Up-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q5T8P6	RBM26	O14757	CHEK1	S184	S178T	178	Missense	distal	-6	no	9.977	10.046	EPSD	GDSC;CCLE	5.604	Up-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q27J81	INF2	O14757	CHEK1	S372	P373L	373	Missense	proximal	1	no	9.890	9.917	EPSD	GDSC;CCLE	5.604	Up-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q27J81	INF2	O14757	CHEK1	S574	R578P	578	Missense	distal	4	no	7.239	7.328	PhosphoSitePlus	GDSC;CCLE	5.604	Up-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q27J81	INF2	O14757	CHEK1	S586	D591N	591	Missense	distal	5	no	7.871	7.782	EPSD	GDSC;CCLE	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q27J81	INF2	O14757	CHEK1	S607	P609L	609	Missense	proximal	2	no	8.081	7.764	EPSD	GDSC;CCLE	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q27J81	INF2	O14757	CHEK1	S1077	R1074K	1074	Missense	distal	-3	no	12.154	8.329	EPSD	GDSC	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	P30304	CDC25A	O14757	CHEK1	S76	G75C	75	Missense	proximal	-1	no	13.331	13.349	PhosphoSitePlus;EPSD	GDSC;CCLE	5.604	Up-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	P30304	CDC25A	O14757	CHEK1	S124	D130G	130	Missense	distal	6	no	10.290	10.685	EPSD;PhosphoSitePlus	GDSC	5.604	Up-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	P30304	CDC25A	O14757	CHEK1	S124	I131V	131	Missense	distal	7	no	10.290	10.710	EPSD;PhosphoSitePlus	GDSC	5.604	Up-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	P30304	CDC25A	O14757	CHEK1	S293	S287N	287	Missense	distal	-6	no	9.771	9.812	EPSD;PhosphoSitePlus	GDSC	5.604	Up-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	P46013	MKI67	O14757	CHEK1	T109	R116H	116	Missense	distal	7	no	7.616	7.323	EPSD	GDSC;CCLE	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	P46013	MKI67	O14757	CHEK1	S125	Q118H	118	Missense	distal	-7	no	7.054	6.737	EPSD	GDSC	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	P46013	MKI67	O14757	CHEK1	S166	D165G	165	Missense	proximal	-1	no	8.077	8.126	EPSD	GDSC;CCLE	5.604	Up-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	P46013	MKI67	O14757	CHEK1	S396	R400*	400	Missense	distal	4	no	9.227	9.361	EPSD	GDSC	5.604	Up-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	P46013	MKI67	O14757	CHEK1	T401	R400*	400	Missense	proximal	-1	no	9.023	9.209	EPSD	GDSC	5.604	Up-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	P46013	MKI67	O14757	CHEK1	S660	S660P	660	Missense	central	0	yes	7.377	0.000	EPSD	GDSC	5.604	Loss
CAMK_CAMKL_CHK1_CHEK1_ST	P46013	MKI67	O14757	CHEK1	S853	K850E	850	Missense	distal	-3	no	9.469	6.206	EPSD	GDSC;CCLE	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	P46013	MKI67	O14757	CHEK1	T1335	G1328V	1328	Missense	distal	-7	no	9.811	9.826	EPSD	GDSC;CCLE	5.604	Up-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	P46013	MKI67	O14757	CHEK1	T1335	R1332W	1332	Missense	distal	-3	no	9.811	-23.792	EPSD	GDSC	5.604	Loss
CAMK_CAMKL_CHK1_CHEK1_ST	P46013	MKI67	O14757	CHEK1	S1533	A1534T	1534	Missense	proximal	1	no	12.861	12.851	EPSD	GDSC;CCLE	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	P46013	MKI67	O14757	CHEK1	S1533	L1527F	1527	Missense	distal	-6	no	12.861	13.111	EPSD	GDSC;CCLE	5.604	Up-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	P46013	MKI67	O14757	CHEK1	S1533	H1539Q	1539	Missense	distal	6	no	12.861	12.567	EPSD	GDSC;CCLE	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	P46013	MKI67	O14757	CHEK1	T1577	A1582V	1582	Missense	distal	5	no	11.310	11.206	EPSD	GDSC;CCLE	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	P46013	MKI67	O14757	CHEK1	T1577	Q1583R	1583	Missense	distal	6	no	11.310	11.317	EPSD	GDSC;CCLE	5.604	Up-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	P46013	MKI67	O14757	CHEK1	T1635	R1632W	1632	Missense	distal	-3	no	7.087	-26.516	EPSD	GDSC	5.604	Loss
CAMK_CAMKL_CHK1_CHEK1_ST	P46013	MKI67	O14757	CHEK1	T1635	S1636F	1636	Missense	proximal	1	no	7.087	7.083	EPSD	GDSC;CCLE	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	P46013	MKI67	O14757	CHEK1	T1764	E1767*	1767	Missense	distal	3	no	9.501	6.604	PhosphoSitePlus	GDSC	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	P46013	MKI67	O14757	CHEK1	T2212	I2205V	2205	Missense	distal	-7	no	5.175	5.611	EPSD	GDSC;CCLE	5.604	Gain
CAMK_CAMKL_CHK1_CHEK1_ST	P46013	MKI67	O14757	CHEK1	S2382	R2379*	2379	Missense	distal	-3	no	9.988	-36.959	EPSD	GDSC	5.604	Loss
CAMK_CAMKL_CHK1_CHEK1_ST	P46013	MKI67	O14757	CHEK1	S2920	T2927A	2927	Missense	distal	7	no	5.683	5.799	EPSD	GDSC;CCLE	5.604	Up-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	P46013	MKI67	O14757	CHEK1	S3041	S3041*	3041	Missense	central	0	yes	11.028	0.000	EPSD	GDSC	5.604	Loss
CAMK_CAMKL_CHK1_CHEK1_ST	Q9UJM3	ERRFI1	O14757	CHEK1	S251	R245K	245	Missense	distal	-6	no	15.938	15.927	EPSD;PhosphoSitePlus	GDSC	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q9UJM3	ERRFI1	O14757	CHEK1	S251	R247K	247	Missense	distal	-4	no	15.938	16.039	EPSD;PhosphoSitePlus	GDSC	5.604	Up-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q9BXW9	FANCD2	O14757	CHEK1	S8	S10P	10	Missense	proximal	2	no	8.107	8.030	EPSD	GDSC	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q9BXW9	FANCD2	O14757	CHEK1	S272	M267I	267	Missense	distal	-5	no	4.404	6.746	EPSD	GDSC;CCLE	5.604	Gain
CAMK_CAMKL_CHK1_CHEK1_ST	Q9BXW9	FANCD2	O14757	CHEK1	S331	A329G	329	Missense	proximal	-2	no	10.926	10.944	PhosphoSitePlus	GDSC	5.604	Up-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q9UKM9	RALY	O14757	CHEK1	T160	R156Q	156	Missense	distal	-4	no	7.506	7.666	PhosphoSitePlus	GDSC;CCLE	5.604	Up-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q9UKM9	RALY	O14757	CHEK1	T160	R157P	157	Missense	distal	-3	no	7.506	0.369	PhosphoSitePlus	GDSC;CCLE	5.604	Loss
CAMK_CAMKL_CHK1_CHEK1_ST	Q14966	ZNF638	O14757	CHEK1	S36	P34H	34	Missense	proximal	-2	no	9.476	9.356	EPSD	GDSC	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q14966	ZNF638	O14757	CHEK1	S36	M32V	32	Missense	distal	-4	no	9.476	9.632	EPSD	GDSC	5.604	Up-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q14966	ZNF638	O14757	CHEK1	S560	R557*	557	Missense	distal	-3	no	8.999	-37.948	EPSD	GDSC	5.604	Loss
CAMK_CAMKL_CHK1_CHEK1_ST	Q14966	ZNF638	O14757	CHEK1	S801	A798D	798	Missense	distal	-3	no	6.110	3.485	EPSD	GDSC	5.604	Loss
CAMK_CAMKL_CHK1_CHEK1_ST	Q14966	ZNF638	O14757	CHEK1	S1052	D1051H	1051	Missense	proximal	-1	no	5.557	5.714	EPSD	GDSC;CCLE	5.604	Gain
CAMK_CAMKL_CHK1_CHEK1_ST	Q14966	ZNF638	O14757	CHEK1	S1468	G1467R	1467	Missense	proximal	-1	no	9.304	9.287	EPSD	GDSC	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q14966	ZNF638	O14757	CHEK1	S1479	Y1483C	1483	Missense	distal	4	no	6.658	6.638	EPSD	GDSC;CCLE	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q14966	ZNF638	O14757	CHEK1	T1487	Y1483C	1483	Missense	distal	-4	no	9.382	9.493	EPSD	GDSC;CCLE	5.604	Up-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q99590	SCAF11	O14757	CHEK1	T331	T327A	327	Missense	distal	-4	no	8.052	8.482	EPSD	GDSC;CCLE	5.604	Up-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q99590	SCAF11	O14757	CHEK1	S902	R908G	908	Missense	distal	6	no	7.337	7.461	EPSD	GDSC	5.604	Up-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q99590	SCAF11	O14757	CHEK1	S911	R908G	908	Missense	distal	-3	no	10.838	3.064	EPSD	GDSC	5.604	Loss
CAMK_CAMKL_CHK1_CHEK1_ST	Q99590	SCAF11	O14757	CHEK1	S943	K950T	950	Missense	distal	7	no	6.778	6.543	EPSD	GDSC;CCLE	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q99590	SCAF11	O14757	CHEK1	S951	K950T	950	Missense	proximal	-1	no	8.936	9.127	EPSD	GDSC;CCLE	5.604	Up-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q99590	SCAF11	O14757	CHEK1	S953	K950T	950	Missense	distal	-3	no	8.300	-8.444	EPSD	GDSC;CCLE	5.604	Loss
CAMK_CAMKL_CHK1_CHEK1_ST	Q99590	SCAF11	O14757	CHEK1	S1127	S1122C	1122	Missense	distal	-5	no	7.093	6.626	PhosphoSitePlus	GDSC;CCLE	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q99590	SCAF11	O14757	CHEK1	S1127	E1130K	1130	Missense	distal	3	no	7.093	6.277	PhosphoSitePlus	GDSC;CCLE	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q99590	SCAF11	O14757	CHEK1	S1170	N1168H	1168	Missense	proximal	-2	no	8.243	8.217	EPSD	GDSC;CCLE	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q9UQ35	SRRM2	O14757	CHEK1	S24	R21H	21	Missense	distal	-3	no	11.692	5.882	EPSD	GDSC;CCLE	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q9UQ35	SRRM2	O14757	CHEK1	T111	A117V	117	Missense	distal	6	no	6.570	6.458	EPSD	GDSC	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q9UQ35	SRRM2	O14757	CHEK1	S212	R219G	219	Missense	distal	7	no	6.451	6.457	EPSD	GDSC	5.604	Up-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q9UQ35	SRRM2	O14757	CHEK1	S220	R219G	219	Missense	proximal	-1	no	8.015	8.032	EPSD	GDSC	5.604	Up-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q9UQ35	SRRM2	O14757	CHEK1	S222	R219G	219	Missense	distal	-3	no	11.709	3.935	EPSD	GDSC	5.604	Loss
CAMK_CAMKL_CHK1_CHEK1_ST	Q9UQ35	SRRM2	O14757	CHEK1	S297	R294Q	294	Missense	distal	-3	no	8.855	1.648	EPSD	GDSC;CCLE	5.604	Loss
CAMK_CAMKL_CHK1_CHEK1_ST	Q9UQ35	SRRM2	O14757	CHEK1	T348	K342R	342	Missense	distal	-6	no	5.816	5.826	EPSD	GDSC;CCLE	5.604	Up-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q9UQ35	SRRM2	O14757	CHEK1	S404	R403P	403	Missense	proximal	-1	no	9.541	9.827	EPSD	GDSC;CCLE	5.604	Up-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q9UQ35	SRRM2	O14757	CHEK1	S506	Q512P	512	Missense	distal	6	no	10.490	11.029	EPSD	GDSC;CCLE	5.604	Up-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q9UQ35	SRRM2	O14757	CHEK1	S510	Q512P	512	Missense	proximal	2	no	8.007	7.497	EPSD	GDSC;CCLE	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q9UQ35	SRRM2	O14757	CHEK1	S518	Q512P	512	Missense	distal	-6	no	9.935	10.031	EPSD	GDSC;CCLE	5.604	Up-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q9UQ35	SRRM2	O14757	CHEK1	S534	P537S	537	Missense	distal	3	no	10.389	10.060	EPSD	GDSC	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q9UQ35	SRRM2	O14757	CHEK1	S536	P537S	537	Missense	proximal	1	no	10.394	10.431	EPSD	GDSC	5.604	Up-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q9UQ35	SRRM2	O14757	CHEK1	S543	P537S	537	Missense	distal	-6	no	5.717	5.620	EPSD	GDSC	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q9UQ35	SRRM2	O14757	CHEK1	S564	S562T	562	Missense	proximal	-2	no	10.230	10.484	EPSD	GDSC;CCLE	5.604	Up-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q9UQ35	SRRM2	O14757	CHEK1	S644	R648C	648	Missense	distal	4	no	6.073	6.177	EPSD	GDSC;CCLE	5.604	Up-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q9UQ35	SRRM2	O14757	CHEK1	S649	R648C	648	Missense	proximal	-1	no	8.534	8.569	EPSD	GDSC;CCLE	5.604	Up-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q9UQ35	SRRM2	O14757	CHEK1	T651	R648C	648	Missense	distal	-3	no	9.375	1.283	EPSD	GDSC;CCLE	5.604	Loss
CAMK_CAMKL_CHK1_CHEK1_ST	Q9UQ35	SRRM2	O14757	CHEK1	S669	R670L	670	Missense	proximal	1	no	8.147	8.113	EPSD	GDSC;CCLE	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q9UQ35	SRRM2	O14757	CHEK1	S671	R670L	670	Missense	proximal	-1	no	10.095	10.194	EPSD	GDSC;CCLE	5.604	Up-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q9UQ35	SRRM2	O14757	CHEK1	T673	R670L	670	Missense	distal	-3	no	9.960	-8.587	EPSD	GDSC;CCLE	5.604	Loss
CAMK_CAMKL_CHK1_CHEK1_ST	Q9UQ35	SRRM2	O14757	CHEK1	T673	R680H	680	Missense	distal	7	no	9.960	9.667	EPSD	GDSC;CCLE	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q9UQ35	SRRM2	O14757	CHEK1	S683	R680H	680	Missense	distal	-3	no	9.973	4.164	EPSD	GDSC;CCLE	5.604	Loss
CAMK_CAMKL_CHK1_CHEK1_ST	Q9UQ35	SRRM2	O14757	CHEK1	T685	R680H	680	Missense	distal	-5	no	9.371	6.906	EPSD	GDSC;CCLE	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q9UQ35	SRRM2	O14757	CHEK1	S702	R705S	705	Missense	distal	3	no	8.184	8.186	EPSD	GDSC	5.604	Up-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q9UQ35	SRRM2	O14757	CHEK1	S704	R705S	705	Missense	proximal	1	no	8.404	8.378	EPSD	GDSC	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q9UQ35	SRRM2	O14757	CHEK1	S706	R705S	705	Missense	proximal	-1	no	7.487	7.326	EPSD	GDSC	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q9UQ35	SRRM2	O14757	CHEK1	T736	R740S	740	Missense	distal	4	no	6.428	6.377	EPSD	GDSC	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q9UQ35	SRRM2	O14757	CHEK1	S743	R740S	740	Missense	distal	-3	no	6.639	-3.057	EPSD	GDSC	5.604	Loss
CAMK_CAMKL_CHK1_CHEK1_ST	Q9UQ35	SRRM2	O14757	CHEK1	S745	R740S	740	Missense	distal	-5	no	8.179	7.967	EPSD	GDSC	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q9UQ35	SRRM2	O14757	CHEK1	S799	P794L	794	Missense	distal	-5	no	5.671	10.378	EPSD	GDSC;CCLE	5.604	Up-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q9UQ35	SRRM2	O14757	CHEK1	S943	P938L	938	Missense	distal	-5	no	3.515	8.221	EPSD	GDSC	5.604	Gain
CAMK_CAMKL_CHK1_CHEK1_ST	Q9UQ35	SRRM2	O14757	CHEK1	S1101	S1099F	1099	Missense	proximal	-2	no	6.646	6.935	EPSD	GDSC;CCLE	5.604	Up-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q9UQ35	SRRM2	O14757	CHEK1	S1140	P1133S	1133	Missense	distal	-7	no	6.166	6.836	EPSD	GDSC;CCLE	5.604	Up-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q9UQ35	SRRM2	O14757	CHEK1	S1214	G1217V	1217	Missense	distal	3	no	6.835	7.261	EPSD	GDSC;CCLE	5.604	Up-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q9UQ35	SRRM2	O14757	CHEK1	S1266	T1265I	1265	Missense	proximal	-1	no	6.016	5.929	EPSD	GDSC;CCLE	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q9UQ35	SRRM2	O14757	CHEK1	S1375	K1372R	1372	Missense	distal	-3	no	2.964	6.789	EPSD	GDSC	5.604	Gain
CAMK_CAMKL_CHK1_CHEK1_ST	Q9UQ35	SRRM2	O14757	CHEK1	S1419	E1426*	1426	Missense	distal	7	no	8.175	6.888	EPSD	GDSC	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q9UQ35	SRRM2	O14757	CHEK1	S1421	E1426*	1426	Missense	distal	5	no	6.266	5.782	EPSD	GDSC	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q9UQ35	SRRM2	O14757	CHEK1	S1436	S1439G	1439	Missense	distal	3	no	12.624	12.537	EPSD	GDSC;CCLE	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q9UQ35	SRRM2	O14757	CHEK1	S1441	S1439G	1439	Missense	proximal	-2	no	7.836	7.968	EPSD	GDSC;CCLE	5.604	Up-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q9UQ35	SRRM2	O14757	CHEK1	S1443	S1439G	1439	Missense	distal	-4	no	5.936	6.270	EPSD	GDSC;CCLE	5.604	Up-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q9UQ35	SRRM2	O14757	CHEK1	S1443	D1449H	1449	Missense	distal	6	no	5.936	6.495	EPSD	GDSC;CCLE	5.604	Up-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q9UQ35	SRRM2	O14757	CHEK1	S1451	D1449H	1449	Missense	proximal	-2	no	9.066	9.182	EPSD	GDSC;CCLE	5.604	Up-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q9UQ35	SRRM2	O14757	CHEK1	S1499	N1506H	1506	Missense	distal	7	no	8.804	8.375	EPSD;PhosphoSitePlus	GDSC	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q9UQ35	SRRM2	O14757	CHEK1	S1501	N1506H	1506	Missense	distal	5	no	8.668	8.583	EPSD	GDSC	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q9UQ35	SRRM2	O14757	CHEK1	S1559	D1560N	1560	Missense	proximal	1	no	7.111	7.003	EPSD	GDSC	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q9UQ35	SRRM2	O14757	CHEK1	S1579	D1586A	1586	Missense	distal	7	no	7.043	6.701	EPSD	GDSC;CCLE	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q9UQ35	SRRM2	O14757	CHEK1	S1581	D1586A	1586	Missense	distal	5	no	7.711	7.643	EPSD	GDSC;CCLE	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q9UQ35	SRRM2	O14757	CHEK1	S1596	R1594W	1594	Missense	proximal	-2	no	6.205	6.326	EPSD	GDSC;CCLE	5.604	Up-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q9UQ35	SRRM2	O14757	CHEK1	S1598	R1594W	1594	Missense	distal	-4	no	6.624	5.862	EPSD	GDSC;CCLE	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q9UQ35	SRRM2	O14757	CHEK1	S1600	R1594W	1594	Missense	distal	-6	no	8.519	8.839	EPSD	GDSC;CCLE	5.604	Up-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q9UQ35	SRRM2	O14757	CHEK1	S1600	D1606H	1606	Missense	distal	6	no	8.519	9.078	EPSD	GDSC;CCLE	5.604	Up-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q9UQ35	SRRM2	O14757	CHEK1	S1640	P1647S	1647	Missense	distal	7	no	7.474	7.419	EPSD	GDSC;CCLE	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q9UQ35	SRRM2	O14757	CHEK1	S1648	P1647S	1647	Missense	proximal	-1	no	12.260	11.813	EPSD	GDSC;CCLE	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q9UQ35	SRRM2	O14757	CHEK1	S1648	S1652I	1652	Missense	distal	4	no	12.260	12.311	EPSD	GDSC;CCLE	5.604	Up-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q9UQ35	SRRM2	O14757	CHEK1	S1690	R1692L	1692	Missense	proximal	2	no	6.896	6.597	EPSD	GDSC;CCLE	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q9UQ35	SRRM2	O14757	CHEK1	S1691	R1692L	1692	Missense	proximal	1	no	5.807	5.772	EPSD	GDSC;CCLE	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q9UQ35	SRRM2	O14757	CHEK1	S1729	S1729L	1729	Missense	central	0	yes	6.212	0.000	EPSD	GDSC;CCLE	5.604	Loss
CAMK_CAMKL_CHK1_CHEK1_ST	Q9UQ35	SRRM2	O14757	CHEK1	S1749	T1756I	1756	Missense	distal	7	no	11.554	11.329	EPSD	GDSC	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q9UQ35	SRRM2	O14757	CHEK1	S1762	T1756I	1756	Missense	distal	-6	no	7.307	7.236	EPSD	GDSC	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q9UQ35	SRRM2	O14757	CHEK1	T1784	R1787C	1787	Missense	distal	3	no	6.236	5.289	EPSD	GDSC	5.604	Loss
CAMK_CAMKL_CHK1_CHEK1_ST	Q9UQ35	SRRM2	O14757	CHEK1	S1791	R1787C	1787	Missense	distal	-4	no	9.800	9.426	EPSD	GDSC	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q9UQ35	SRRM2	O14757	CHEK1	S1793	R1787C	1787	Missense	distal	-6	no	10.373	10.489	EPSD	GDSC	5.604	Up-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q9UQ35	SRRM2	O14757	CHEK1	S1842	S1842C	1842	Missense	central	0	yes	9.900	0.000	EPSD	GDSC;CCLE	5.604	Loss
CAMK_CAMKL_CHK1_CHEK1_ST	Q9UQ35	SRRM2	O14757	CHEK1	T1844	S1842C	1842	Missense	proximal	-2	no	8.740	8.787	EPSD	GDSC;CCLE	5.604	Up-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q9UQ35	SRRM2	O14757	CHEK1	S1866	R1867G	1867	Missense	proximal	1	no	10.039	10.030	EPSD	GDSC	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q9UQ35	SRRM2	O14757	CHEK1	S1878	R1875*	1875	Missense	distal	-3	no	6.953	-39.994	EPSD	GDSC	5.604	Loss
CAMK_CAMKL_CHK1_CHEK1_ST	Q9UQ35	SRRM2	O14757	CHEK1	T1880	R1875*	1875	Missense	distal	-5	no	6.239	5.678	EPSD	GDSC	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q9UQ35	SRRM2	O14757	CHEK1	S1937	R1944C	1944	Missense	distal	7	no	8.934	8.528	EPSD	GDSC;CCLE	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q9UQ35	SRRM2	O14757	CHEK1	T1939	R1944C	1944	Missense	distal	5	no	8.050	7.806	EPSD	GDSC;CCLE	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q9UQ35	SRRM2	O14757	CHEK1	T1941	R1944C	1944	Missense	distal	3	no	10.178	9.231	EPSD	GDSC;CCLE	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q9UQ35	SRRM2	O14757	CHEK1	S1946	R1944C	1944	Missense	proximal	-2	no	11.287	11.236	EPSD	GDSC;CCLE	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q9UQ35	SRRM2	O14757	CHEK1	S1948	R1944C	1944	Missense	distal	-4	no	10.690	10.316	EPSD	GDSC;CCLE	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q9UQ35	SRRM2	O14757	CHEK1	T1950	R1944C	1944	Missense	distal	-6	no	9.383	9.499	EPSD	GDSC;CCLE	5.604	Up-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q9UQ35	SRRM2	O14757	CHEK1	S2032	R2039H	2039	Missense	distal	7	no	12.257	11.964	EPSD	GDSC	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q9UQ35	SRRM2	O14757	CHEK1	T2034	R2039H	2039	Missense	distal	5	no	6.689	6.705	EPSD	GDSC	5.604	Up-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q9UQ35	SRRM2	O14757	CHEK1	S2042	R2039H	2039	Missense	distal	-3	no	12.881	7.072	EPSD	GDSC	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q9UQ35	SRRM2	O14757	CHEK1	S2044	R2039H	2039	Missense	distal	-5	no	9.101	6.636	EPSD	GDSC	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q9UQ35	SRRM2	O14757	CHEK1	S2046	R2052P	2052	Missense	distal	6	no	8.169	8.701	EPSD	GDSC	5.604	Up-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q9UQ35	SRRM2	O14757	CHEK1	S2046	R2052C	2052	Missense	distal	6	no	8.169	8.463	EPSD	GDSC	5.604	Up-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q9UQ35	SRRM2	O14757	CHEK1	S2046	R2039H	2039	Missense	distal	-7	no	8.169	8.110	EPSD	GDSC	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q9UQ35	SRRM2	O14757	CHEK1	S2054	R2052P	2052	Missense	proximal	-2	no	7.310	7.495	EPSD	GDSC	5.604	Up-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q9UQ35	SRRM2	O14757	CHEK1	S2054	R2052C	2052	Missense	proximal	-2	no	7.310	7.259	EPSD	GDSC	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q9UQ35	SRRM2	O14757	CHEK1	S2054	R2057H	2057	Missense	distal	3	no	7.310	7.341	EPSD	GDSC;CCLE	5.604	Up-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q9UQ35	SRRM2	O14757	CHEK1	S2056	R2052P	2052	Missense	distal	-4	no	10.857	10.785	EPSD	GDSC	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q9UQ35	SRRM2	O14757	CHEK1	S2056	R2052C	2052	Missense	distal	-4	no	10.857	10.483	EPSD	GDSC	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q9UQ35	SRRM2	O14757	CHEK1	S2056	R2057H	2057	Missense	proximal	1	no	10.857	10.791	EPSD	GDSC;CCLE	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q9UQ35	SRRM2	O14757	CHEK1	T2058	R2052P	2052	Missense	distal	-6	no	7.889	8.067	EPSD	GDSC	5.604	Up-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q9UQ35	SRRM2	O14757	CHEK1	T2058	R2052C	2052	Missense	distal	-6	no	7.889	8.005	EPSD	GDSC	5.604	Up-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q9UQ35	SRRM2	O14757	CHEK1	T2058	R2057H	2057	Missense	proximal	-1	no	7.889	8.015	EPSD	GDSC;CCLE	5.604	Up-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q9UQ35	SRRM2	O14757	CHEK1	T2247	T2252A	2252	Missense	distal	5	no	5.444	5.685	EPSD	GDSC;CCLE	5.604	Gain
CAMK_CAMKL_CHK1_CHEK1_ST	Q9UQ35	SRRM2	O14757	CHEK1	T2261	N2255I	2255	Missense	distal	-6	no	5.910	5.868	EPSD	GDSC;CCLE	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q9UQ35	SRRM2	O14757	CHEK1	T2316	T2316I	2316	Missense	central	0	yes	6.674	0.000	EPSD	GDSC;CCLE	5.604	Loss
CAMK_CAMKL_CHK1_CHEK1_ST	Q9UQ35	SRRM2	O14757	CHEK1	T2316	A2321T	2321	Missense	distal	5	no	6.674	6.433	EPSD	GDSC;CCLE	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q9UQ35	SRRM2	O14757	CHEK1	T2397	S2394R	2394	Missense	distal	-3	no	-3.791	5.905	EPSD	GDSC;CCLE	5.604	Gain
CAMK_CAMKL_CHK1_CHEK1_ST	Q9UQ35	SRRM2	O14757	CHEK1	S2407	P2414Q	2414	Missense	distal	7	no	13.696	13.888	EPSD	GDSC	5.604	Up-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q9UQ35	SRRM2	O14757	CHEK1	T2409	P2414Q	2414	Missense	distal	5	no	6.681	6.736	EPSD	GDSC	5.604	Up-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q9UQ35	SRRM2	O14757	CHEK1	S2421	P2414Q	2414	Missense	distal	-7	no	7.443	8.111	EPSD	GDSC	5.604	Up-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q9UQ35	SRRM2	O14757	CHEK1	S2533	R2530W	2530	Missense	distal	-3	no	7.570	-26.033	EPSD	GDSC;CCLE	5.604	Loss
CAMK_CAMKL_CHK1_CHEK1_ST	Q9UQ35	SRRM2	O14757	CHEK1	S2608	S2613R	2613	Missense	distal	5	no	6.702	6.599	EPSD	GDSC;CCLE	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q9UQ35	SRRM2	O14757	CHEK1	S2608	R2606H	2606	Missense	proximal	-2	no	6.702	6.767	EPSD	GDSC;CCLE	5.604	Up-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q9UQ35	SRRM2	O14757	CHEK1	S2609	S2613R	2613	Missense	distal	4	no	8.854	8.904	EPSD	GDSC;CCLE	5.604	Up-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q9UQ35	SRRM2	O14757	CHEK1	S2609	R2606H	2606	Missense	distal	-3	no	8.854	3.044	EPSD	GDSC;CCLE	5.604	Loss
CAMK_CAMKL_CHK1_CHEK1_ST	Q9UQ35	SRRM2	O14757	CHEK1	S2692	R2699H	2699	Missense	distal	7	no	6.488	6.195	EPSD	GDSC;CCLE	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q9UQ35	SRRM2	O14757	CHEK1	S2702	R2699H	2699	Missense	distal	-3	no	8.080	2.270	EPSD	GDSC;CCLE	5.604	Loss
CAMK_CAMKL_CHK1_CHEK1_ST	Q9P2D1	CHD7	O14757	CHEK1	S417	P415L	415	Missense	proximal	-2	no	9.414	9.235	EPSD	GDSC;CCLE	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q9P2D1	CHD7	O14757	CHEK1	S417	G416R	416	Missense	proximal	-1	no	9.414	9.397	EPSD	GDSC;CCLE	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q9P2D1	CHD7	O14757	CHEK1	T689	T687A	687	Missense	proximal	-2	no	7.870	7.731	EPSD	GDSC	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q9P2D1	CHD7	O14757	CHEK1	T689	K683E	683	Missense	distal	-6	no	7.870	7.838	EPSD	GDSC	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q9P2D1	CHD7	O14757	CHEK1	T689	K683T	683	Missense	distal	-6	no	7.870	8.030	EPSD	GDSC	5.604	Up-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q9P2D1	CHD7	O14757	CHEK1	T1227	E1223Q	1223	Missense	distal	-4	no	6.721	6.678	PhosphoSitePlus	GDSC;CCLE	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q9P2D1	CHD7	O14757	CHEK1	S1566	S1566I	1566	Missense	central	0	yes	8.900	0.000	EPSD	GDSC;CCLE	5.604	Loss
CAMK_CAMKL_CHK1_CHEK1_ST	Q9P2D1	CHD7	O14757	CHEK1	T1635	E1636K	1636	Missense	proximal	1	no	9.656	9.582	EPSD	GDSC;CCLE	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q9P2D1	CHD7	O14757	CHEK1	T1635	V1639I	1639	Missense	distal	4	no	9.656	9.596	EPSD	GDSC;CCLE	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q9P2D1	CHD7	O14757	CHEK1	T2350	P2347S	2347	Missense	distal	-3	no	6.411	3.852	EPSD	GDSC;CCLE	5.604	Loss
CAMK_CAMKL_CHK1_CHEK1_ST	Q9P2D1	CHD7	O14757	CHEK1	T2350	P2357S	2357	Missense	distal	7	no	6.411	6.356	EPSD	GDSC;CCLE	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q9P2D1	CHD7	O14757	CHEK1	T2494	N2499D	2499	Missense	distal	5	no	11.447	11.536	EPSD	GDSC;CCLE	5.604	Up-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q13439	GOLGA4	O14757	CHEK1	S37	S40Y	40	Missense	distal	3	no	8.135	6.908	EPSD	GDSC;CCLE	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q13439	GOLGA4	O14757	CHEK1	T39	S40Y	40	Missense	proximal	1	no	8.217	8.200	EPSD	GDSC;CCLE	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q13439	GOLGA4	O14757	CHEK1	S41	S40Y	40	Missense	proximal	-1	no	6.884	7.213	EPSD	GDSC;CCLE	5.604	Up-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q13439	GOLGA4	O14757	CHEK1	S179	S185L	185	Missense	distal	6	no	6.395	6.804	EPSD	GDSC;CCLE	5.604	Up-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q9UEY8	ADD3	O14757	CHEK1	S42	R46*	46	Missense	distal	4	no	7.170	7.303	EPSD	GDSC	5.604	Up-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q9UEY8	ADD3	O14757	CHEK1	T651	T653I	653	Missense	proximal	2	no	6.124	6.009	EPSD	GDSC;CCLE	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q9UEY8	ADD3	O14757	CHEK1	S693	K688E	688	Missense	distal	-5	no	8.097	5.535	PhosphoSitePlus	GDSC;CCLE	5.604	Loss
CAMK_CAMKL_CHK1_CHEK1_ST	Q9BW19	KIFC1	O14757	CHEK1	S71	V69I	69	Missense	proximal	-2	no	5.969	5.906	EPSD	GDSC;CCLE	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q9BW19	KIFC1	O14757	CHEK1	T326	G323A	323	Missense	distal	-3	no	4.733	5.796	EPSD	GDSC	5.604	Gain
CAMK_CAMKL_CHK1_CHEK1_ST	Q9BW19	KIFC1	O14757	CHEK1	T359	S361G	361	Missense	proximal	2	no	7.057	6.992	EPSD	GDSC;CCLE	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q96T58	SPEN	O14757	CHEK1	S278	D282E	282	Missense	distal	4	no	7.149	7.057	EPSD	GDSC;CCLE	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q96T58	SPEN	O14757	CHEK1	S278	S283*	283	Missense	distal	5	no	7.149	6.750	EPSD	GDSC	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q96T58	SPEN	O14757	CHEK1	T534	Q531R	531	Missense	distal	-3	no	2.558	9.765	EPSD	GDSC;CCLE	5.604	Gain
CAMK_CAMKL_CHK1_CHEK1_ST	Q96T58	SPEN	O14757	CHEK1	S646	P651L	651	Missense	distal	5	no	6.338	6.176	EPSD	GDSC;CCLE	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q96T58	SPEN	O14757	CHEK1	S727	R733C	733	Missense	distal	6	no	8.901	9.195	EPSD	GDSC	5.604	Up-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q96T58	SPEN	O14757	CHEK1	S736	R733C	733	Missense	distal	-3	no	13.238	5.147	EPSD	GDSC	5.604	Loss
CAMK_CAMKL_CHK1_CHEK1_ST	Q96T58	SPEN	O14757	CHEK1	S749	Y756*	756	Missense	distal	7	no	7.076	6.637	EPSD	GDSC	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q96T58	SPEN	O14757	CHEK1	S749	E752Q	752	Missense	distal	3	no	7.076	6.676	EPSD	GDSC;CCLE	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q96T58	SPEN	O14757	CHEK1	S757	Y756*	756	Missense	proximal	-1	no	6.656	6.674	EPSD	GDSC	5.604	Up-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q96T58	SPEN	O14757	CHEK1	S757	E752Q	752	Missense	distal	-5	no	6.656	7.646	EPSD	GDSC;CCLE	5.604	Up-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q96T58	SPEN	O14757	CHEK1	S946	E950D	950	Missense	distal	4	no	6.815	6.907	EPSD	GDSC;CCLE	5.604	Up-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q96T58	SPEN	O14757	CHEK1	S1082	R1079S	1079	Missense	distal	-3	no	8.936	-0.760	EPSD	GDSC;CCLE	5.604	Loss
CAMK_CAMKL_CHK1_CHEK1_ST	Q96T58	SPEN	O14757	CHEK1	S1168	H1165R	1165	Missense	distal	-3	no	2.935	8.744	EPSD	GDSC;CCLE	5.604	Gain
CAMK_CAMKL_CHK1_CHEK1_ST	Q96T58	SPEN	O14757	CHEK1	S1252	T1258S	1258	Missense	distal	6	no	9.043	8.732	EPSD	GDSC;CCLE	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q96T58	SPEN	O14757	CHEK1	S1369	R1371*	1371	Missense	proximal	2	no	9.734	9.130	EPSD	GDSC	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q96T58	SPEN	O14757	CHEK1	S1369	S1364G	1364	Missense	distal	-5	no	9.734	9.780	EPSD	GDSC	5.604	Up-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q96T58	SPEN	O14757	CHEK1	S1424	S1424G	1424	Missense	central	0	yes	9.156	0.000	EPSD	GDSC	5.604	Loss
CAMK_CAMKL_CHK1_CHEK1_ST	Q96T58	SPEN	O14757	CHEK1	S1424	D1419G	1419	Missense	distal	-5	no	9.156	9.978	EPSD	GDSC;CCLE	5.604	Up-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q96T58	SPEN	O14757	CHEK1	S1453	E1449Q	1449	Missense	distal	-4	no	13.331	13.288	EPSD	GDSC;CCLE	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q96T58	SPEN	O14757	CHEK1	T1826	A1831T	1831	Missense	distal	5	no	7.038	6.797	EPSD	GDSC;CCLE	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q96T58	SPEN	O14757	CHEK1	T1826	Q1829*	1829	Missense	distal	3	no	7.038	4.542	EPSD	GDSC	5.604	Loss
CAMK_CAMKL_CHK1_CHEK1_ST	Q96T58	SPEN	O14757	CHEK1	S2407	Q2413*	2413	Missense	distal	6	no	6.767	7.459	EPSD	GDSC	5.604	Up-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q96T58	SPEN	O14757	CHEK1	T2423	P2428T	2428	Missense	distal	5	no	6.850	6.709	EPSD	GDSC;CCLE	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q96T58	SPEN	O14757	CHEK1	T2423	S2426F	2426	Missense	distal	3	no	6.850	7.038	EPSD	GDSC	5.604	Up-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q96T58	SPEN	O14757	CHEK1	S2512	S2515F	2515	Missense	distal	3	no	5.483	5.671	EPSD	GDSC;CCLE	5.604	Gain
CAMK_CAMKL_CHK1_CHEK1_ST	Q96T58	SPEN	O14757	CHEK1	T3102	S3107N	3107	Missense	distal	5	no	6.301	6.299	EPSD	GDSC;CCLE	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q9NRM7	LATS2	O14757	CHEK1	S380	G385S	385	Missense	distal	5	no	16.516	16.707	EPSD	GDSC	5.604	Up-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q9NRM7	LATS2	O14757	CHEK1	S380	T374P	374	Missense	distal	-6	no	16.516	16.544	EPSD	GDSC	5.604	Up-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q9NRM7	LATS2	O14757	CHEK1	S598	S592L	592	Missense	distal	-6	no	6.398	6.422	EPSD	GDSC	5.604	Up-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q9NRM7	LATS2	O14757	CHEK1	S835	W842L	842	Missense	distal	7	no	7.876	8.277	PhosphoSitePlus;EPSD	GDSC;CCLE	5.604	Up-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q9NRM7	LATS2	O14757	CHEK1	S839	W842L	842	Missense	distal	3	no	5.616	5.323	EPSD	GDSC;CCLE	5.604	Loss
CAMK_CAMKL_CHK1_CHEK1_ST	Q5UIP0	RIF1	O14757	CHEK1	S740	M739I	739	Missense	proximal	-1	no	7.255	7.162	EPSD	GDSC;CCLE	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q5UIP0	RIF1	O14757	CHEK1	S782	Q777*	777	Missense	distal	-5	no	6.330	6.166	EPSD	GDSC	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q5UIP0	RIF1	O14757	CHEK1	S1184	S1189P	1189	Missense	distal	5	no	7.967	7.885	EPSD	GDSC;CCLE	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q5UIP0	RIF1	O14757	CHEK1	S1236	N1241D	1241	Missense	distal	5	no	7.864	7.953	EPSD	GDSC	5.604	Up-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q5UIP0	RIF1	O14757	CHEK1	S1418	R1419W	1419	Missense	proximal	1	no	8.615	8.585	EPSD	GDSC;CCLE	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q5UIP0	RIF1	O14757	CHEK1	S1418	R1420*	1420	Missense	proximal	2	no	8.615	8.012	EPSD	GDSC	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q5UIP0	RIF1	O14757	CHEK1	S1422	R1419W	1419	Missense	distal	-3	no	7.244	-26.360	EPSD	GDSC;CCLE	5.604	Loss
CAMK_CAMKL_CHK1_CHEK1_ST	Q5UIP0	RIF1	O14757	CHEK1	S1422	R1420*	1420	Missense	proximal	-2	no	7.244	7.344	EPSD	GDSC	5.604	Up-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q5UIP0	RIF1	O14757	CHEK1	S1579	S1576R	1576	Missense	distal	-3	no	-3.511	6.185	EPSD	GDSC;CCLE	5.604	Gain
CAMK_CAMKL_CHK1_CHEK1_ST	Q5UIP0	RIF1	O14757	CHEK1	T1656	E1655Q	1655	Missense	proximal	-1	no	6.845	6.951	EPSD	GDSC;CCLE	5.604	Up-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q5UIP0	RIF1	O14757	CHEK1	S1688	R1686*	1686	Missense	proximal	-2	no	8.193	8.293	EPSD	GDSC	5.604	Up-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q5UIP0	RIF1	O14757	CHEK1	S1793	D1789G	1789	Missense	distal	-4	no	6.332	6.296	EPSD	GDSC;CCLE	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q5UIP0	RIF1	O14757	CHEK1	S2393	S2391T	2391	Missense	proximal	-2	no	6.016	6.270	EPSD	GDSC;CCLE	5.604	Up-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q96GD4	AURKB	O14757	CHEK1	S331	P325S	325	Missense	distal	-6	no	7.984	7.887	PhosphoSitePlus	GDSC	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q9NXE8	CWC25	O14757	CHEK1	S195	R198C	198	Missense	distal	3	no	9.059	8.112	EPSD	GDSC;CCLE	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q9NXE8	CWC25	O14757	CHEK1	S201	R198C	198	Missense	distal	-3	no	8.239	0.148	EPSD	GDSC;CCLE	5.604	Loss
CAMK_CAMKL_CHK1_CHEK1_ST	Q9NXE8	CWC25	O14757	CHEK1	S272	R277G	277	Missense	distal	5	no	5.663	5.575	EPSD	GDSC;CCLE	5.604	Loss
CAMK_CAMKL_CHK1_CHEK1_ST	Q9NXE8	CWC25	O14757	CHEK1	S295	S299R	299	Missense	distal	4	no	8.612	8.662	EPSD	GDSC	5.604	Up-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q9NXE8	CWC25	O14757	CHEK1	T311	T314A	314	Missense	distal	3	no	10.509	10.747	EPSD	GDSC	5.604	Up-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q9NXE8	CWC25	O14757	CHEK1	S318	T314A	314	Missense	distal	-4	no	9.670	10.100	EPSD	GDSC	5.604	Up-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q9NXE8	CWC25	O14757	CHEK1	S337	E339*	339	Missense	proximal	2	no	9.505	8.257	PhosphoSitePlus	GDSC	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q9NXE8	CWC25	O14757	CHEK1	S337	G331R	331	Missense	distal	-6	no	9.505	9.387	PhosphoSitePlus	GDSC	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q96PK6	RBM14	O14757	CHEK1	T206	T206I	206	Missense	central	0	yes	7.813	0.000	EPSD	GDSC;CCLE	5.604	Loss
CAMK_CAMKL_CHK1_CHEK1_ST	Q96PK6	RBM14	O14757	CHEK1	S294	A297T	297	Missense	distal	3	no	5.932	5.695	EPSD	GDSC;CCLE	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q96PK6	RBM14	O14757	CHEK1	S520	A513E	513	Missense	distal	-7	no	10.194	9.967	EPSD	GDSC;CCLE	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q9Y520	PRRC2C	O14757	CHEK1	S453	R450G	450	Missense	distal	-3	no	8.461	0.687	EPSD	GDSC	5.604	Loss
CAMK_CAMKL_CHK1_CHEK1_ST	O75151	PHF2	O14757	CHEK1	S474	E468*	468	Missense	distal	-6	no	5.381	5.726	EPSD	GDSC	5.604	Gain
CAMK_CAMKL_CHK1_CHEK1_ST	O75151	PHF2	O14757	CHEK1	S929	G924C	924	Missense	distal	-5	no	8.732	8.218	PhosphoSitePlus	GDSC;CCLE	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	P52272	HNRNPM	O14757	CHEK1	S124	E130*	130	Missense	distal	6	no	4.791	5.834	EPSD	GDSC	5.604	Gain
CAMK_CAMKL_CHK1_CHEK1_ST	P52272	HNRNPM	O14757	CHEK1	S204	L202I	202	Missense	proximal	-2	no	7.595	7.618	EPSD	GDSC;CCLE	5.604	Up-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	P52272	HNRNPM	O14757	CHEK1	S225	V230G	230	Missense	distal	5	no	7.770	7.664	EPSD	GDSC	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	P52272	HNRNPM	O14757	CHEK1	S446	G451D	451	Missense	distal	5	no	8.749	9.027	EPSD	GDSC;CCLE	5.604	Up-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	P52272	HNRNPM	O14757	CHEK1	S452	G451D	451	Missense	proximal	-1	no	10.492	10.443	EPSD	GDSC;CCLE	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	P52272	HNRNPM	O14757	CHEK1	S481	R478H	478	Missense	distal	-3	no	10.530	4.720	EPSD	GDSC;CCLE	5.604	Loss
CAMK_CAMKL_CHK1_CHEK1_ST	Q15648	MED1	O14757	CHEK1	S256	R249G	249	Missense	distal	-7	no	6.456	6.494	EPSD	GDSC	5.604	Up-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q15648	MED1	O14757	CHEK1	S256	S250F	250	Missense	distal	-6	no	6.456	6.730	EPSD	GDSC;CCLE	5.604	Up-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q15648	MED1	O14757	CHEK1	S503	R500*	500	Missense	distal	-3	no	7.993	-38.954	EPSD	GDSC	5.604	Loss
CAMK_CAMKL_CHK1_CHEK1_ST	Q15648	MED1	O14757	CHEK1	S503	C501Y	501	Missense	proximal	-2	no	7.993	8.058	EPSD	GDSC;CCLE	5.604	Up-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q15648	MED1	O14757	CHEK1	S671	G674S	674	Missense	distal	3	no	12.462	12.549	EPSD	GDSC	5.604	Up-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q15648	MED1	O14757	CHEK1	S671	M678I	678	Missense	distal	7	no	12.462	12.185	EPSD	GDSC;CCLE	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q15648	MED1	O14757	CHEK1	S771	D778N	778	Missense	distal	7	no	7.402	7.240	EPSD	GDSC;CCLE	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q15648	MED1	O14757	CHEK1	S951	M947T	947	Missense	distal	-4	no	8.786	8.590	EPSD	GDSC;CCLE	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q15648	MED1	O14757	CHEK1	S1207	G1201V	1201	Missense	distal	-6	no	5.984	5.958	EPSD	GDSC;CCLE	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q16204	CCDC6	O14757	CHEK1	S419	P412A	412	Missense	distal	-7	no	6.785	7.905	EPSD	GDSC;CCLE	5.604	Up-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q16204	CCDC6	O14757	CHEK1	S464	S459L	459	Missense	distal	-5	no	2.486	5.674	EPSD	GDSC	5.604	Gain
CAMK_CAMKL_CHK1_CHEK1_ST	Q9Y2T7	YBX2	O14757	CHEK1	T115	G108R	108	Missense	distal	-7	no	11.717	11.679	PhosphoSitePlus	GDSC;CCLE	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q9Y2T7	YBX2	O14757	CHEK1	T115	D114Y	114	Missense	proximal	-1	no	11.717	11.917	PhosphoSitePlus	GDSC;CCLE	5.604	Up-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q9Y2T7	YBX2	O14757	CHEK1	S189	M195I	195	Missense	distal	6	no	12.256	11.898	EPSD	GDSC;CCLE	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q9Y2T7	YBX2	O14757	CHEK1	S189	F183S	183	Missense	distal	-6	no	12.256	11.983	EPSD	GDSC;CCLE	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q86WB0	ZC3HC1	O14757	CHEK1	T379	R374G	374	Missense	distal	-5	no	9.170	9.005	EPSD	GDSC;CCLE	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q86WB0	ZC3HC1	O14757	CHEK1	S407	K401Q	401	Missense	distal	-6	no	13.059	13.151	EPSD	GDSC	5.604	Up-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q86WB0	ZC3HC1	O14757	CHEK1	S407	K401E	401	Missense	distal	-6	no	13.059	13.027	EPSD	GDSC;CCLE	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q86WB0	ZC3HC1	O14757	CHEK1	S471	T477M	477	Missense	distal	6	no	8.256	8.347	EPSD	GDSC;CCLE	5.604	Up-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q86WB0	ZC3HC1	O14757	CHEK1	S471	H468Y	468	Missense	distal	-3	no	8.256	-2.878	EPSD	GDSC;CCLE	5.604	Loss
CAMK_CAMKL_CHK1_CHEK1_ST	P08631	HCK	O14757	CHEK1	T36	G33R	33	Missense	distal	-3	no	-1.624	6.150	EPSD	GDSC	5.604	Gain
CAMK_CAMKL_CHK1_CHEK1_ST	P08631	HCK	O14757	CHEK1	S181	V184M	184	Missense	distal	3	no	5.617	5.191	EPSD	GDSC	5.604	Loss
CAMK_CAMKL_CHK1_CHEK1_ST	P49790	NUP153	O14757	CHEK1	S320	K317N	317	Missense	distal	-3	no	7.054	0.511	EPSD	GDSC;CCLE	5.604	Loss
CAMK_CAMKL_CHK1_CHEK1_ST	P49790	NUP153	O14757	CHEK1	S359	Q360E	360	Missense	proximal	1	no	6.536	6.602	EPSD	GDSC;CCLE	5.604	Up-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	P49790	NUP153	O14757	CHEK1	S359	V357E	357	Missense	proximal	-2	no	6.536	6.406	EPSD	GDSC	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	P49790	NUP153	O14757	CHEK1	S607	D610A	610	Missense	distal	3	no	7.698	6.235	EPSD	GDSC	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	P49790	NUP153	O14757	CHEK1	S1019	S1019F	1019	Missense	central	0	yes	9.747	0.000	EPSD	GDSC;CCLE	5.604	Loss
CAMK_CAMKL_CHK1_CHEK1_ST	Q9NWH9	SLTM	O14757	CHEK1	S330	S324N	324	Missense	distal	-6	no	6.399	6.440	EPSD	GDSC;CCLE	5.604	Up-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q9NWH9	SLTM	O14757	CHEK1	S962	E955Q	955	Missense	distal	-7	no	9.658	9.433	EPSD	GDSC;CCLE	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q9NWH9	SLTM	O14757	CHEK1	S973	G970R	970	Missense	distal	-3	no	0.842	8.617	EPSD	GDSC;CCLE	5.604	Gain
CAMK_CAMKL_CHK1_CHEK1_ST	O15294	OGT	O14757	CHEK1	S20	A25V	25	Missense	distal	5	no	11.636	11.532	PhosphoSitePlus	GDSC;CCLE	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	O15294	OGT	O14757	CHEK1	S491	R485L	485	Missense	distal	-6	no	5.861	5.965	EPSD	GDSC;CCLE	5.604	Up-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	P10636	MAPT	O14757	CHEK1	S171	D177V	177	Missense	distal	6	no	5.554	6.014	EPSD	GDSC	5.604	Gain
CAMK_CAMKL_CHK1_CHEK1_ST	P10636	MAPT	O14757	CHEK1	S214	V218G	218	Missense	distal	4	no	12.525	12.481	EPSD	GDSC	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	P10636	MAPT	O14757	CHEK1	S341	P340L	340	Missense	proximal	-1	no	10.855	10.669	EPSD	GDSC;CCLE	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	P10636	MAPT	O14757	CHEK1	S341	G339S	339	Missense	proximal	-2	no	10.855	10.722	EPSD	GDSC;CCLE	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	P10636	MAPT	O14757	CHEK1	S637	V635I	635	Missense	proximal	-2	no	7.829	7.766	EPSD	GDSC	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	P10636	MAPT	O14757	CHEK1	S641	V635I	635	Missense	distal	-6	no	9.317	9.304	EPSD	GDSC	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q14676	MDC1	O14757	CHEK1	S168	R161G	161	Missense	distal	-7	no	6.964	7.002	EPSD	GDSC;CCLE	5.604	Up-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q14676	MDC1	O14757	CHEK1	S485	L480F	480	Missense	distal	-5	no	13.565	10.001	EPSD	GDSC	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q14676	MDC1	O14757	CHEK1	S981	T980I	980	Missense	proximal	-1	no	5.787	5.700	EPSD	GDSC;CCLE	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q14676	MDC1	O14757	CHEK1	S1086	Q1083H	1083	Missense	distal	-3	no	4.931	6.328	EPSD	GDSC;CCLE	5.604	Gain
CAMK_CAMKL_CHK1_CHEK1_ST	Q14676	MDC1	O14757	CHEK1	T1179	Q1176R	1176	Missense	distal	-3	no	1.876	9.083	EPSD	GDSC	5.604	Gain
CAMK_CAMKL_CHK1_CHEK1_ST	Q14676	MDC1	O14757	CHEK1	T1220	A1227V	1227	Missense	distal	7	no	8.632	8.711	EPSD	GDSC	5.604	Up-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q14676	MDC1	O14757	CHEK1	T1295	V1301L	1301	Missense	distal	6	no	8.594	8.727	EPSD	GDSC	5.604	Up-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q14676	MDC1	O14757	CHEK1	T1302	V1301L	1301	Missense	proximal	-1	no	8.841	8.846	EPSD	GDSC	5.604	Up-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q14676	MDC1	O14757	CHEK1	S1702	E1699K	1699	Missense	distal	-3	no	4.355	7.618	EPSD	GDSC;CCLE	5.604	Gain
CAMK_CAMKL_CHK1_CHEK1_ST	Q14676	MDC1	O14757	CHEK1	S1814	R1811L	1811	Missense	distal	-3	no	8.693	-9.854	EPSD	GDSC;CCLE	5.604	Loss
CAMK_CAMKL_CHK1_CHEK1_ST	P52292	KPNA2	O14757	CHEK1	T230	T230A	230	Missense	central	0	yes	5.966	0.000	EPSD	GDSC;CCLE	5.604	Loss
CAMK_CAMKL_CHK1_CHEK1_ST	P52292	KPNA2	O14757	CHEK1	T230	N228D	228	Missense	proximal	-2	no	5.966	5.824	EPSD	GDSC;CCLE	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	P25205	MCM3	O14757	CHEK1	S160	A167S	167	Missense	distal	7	no	12.830	12.780	PhosphoSitePlus	GDSC;CCLE	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	P25205	MCM3	O14757	CHEK1	S564	M562I	562	Missense	proximal	-2	no	6.591	6.577	EPSD	GDSC;CCLE	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	O95707	POP4	O14757	CHEK1	S10	Y6C	6	Missense	distal	-4	no	6.269	6.380	PhosphoSitePlus	GDSC;CCLE	5.604	Up-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	P35612	ADD2	O14757	CHEK1	S62	P61L	61	Missense	proximal	-1	no	6.159	5.973	EPSD	GDSC	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	P35612	ADD2	O14757	CHEK1	S396	E390K	390	Missense	distal	-6	no	10.020	10.052	EPSD	GDSC	5.604	Up-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	P35612	ADD2	O14757	CHEK1	S667	S667N	667	Missense	central	0	yes	6.906	0.000	EPSD	GDSC;CCLE	5.604	Loss
CAMK_CAMKL_CHK1_CHEK1_ST	P35612	ADD2	O14757	CHEK1	T671	S667N	667	Missense	distal	-4	no	6.141	6.436	EPSD	GDSC;CCLE	5.604	Up-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	P35612	ADD2	O14757	CHEK1	T711	R710Q	710	Missense	proximal	-1	no	6.300	6.316	EPSD	GDSC;CCLE	5.604	Up-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	P35612	ADD2	O14757	CHEK1	S713	R710Q	710	Missense	distal	-3	no	8.097	0.891	PhosphoSitePlus	GDSC;CCLE	5.604	Loss
CAMK_CAMKL_CHK1_CHEK1_ST	P35611	ADD1	O14757	CHEK1	S408	S415T	415	Missense	distal	7	no	8.571	8.504	EPSD	GDSC	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	P35611	ADD1	O14757	CHEK1	S408	E411A	411	Missense	distal	3	no	8.571	7.205	EPSD	GDSC;CCLE	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	P35611	ADD1	O14757	CHEK1	S408	A414V	414	Missense	distal	6	no	8.571	8.459	EPSD	GDSC;CCLE	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	P35611	ADD1	O14757	CHEK1	T482	H478Y	478	Missense	distal	-4	no	8.115	7.827	EPSD	GDSC	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q6UB98	ANKRD12	O14757	CHEK1	S526	D529G	529	Missense	distal	3	no	7.615	5.970	EPSD	GDSC;CCLE	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q6UB98	ANKRD12	O14757	CHEK1	S1047	A1049S	1049	Missense	proximal	2	no	10.093	9.637	EPSD	GDSC	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q6UB98	ANKRD12	O14757	CHEK1	S1056	A1049S	1049	Missense	distal	-7	no	6.113	5.663	EPSD	GDSC	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q6UB98	ANKRD12	O14757	CHEK1	S1056	K1055R	1055	Missense	proximal	-1	no	6.113	6.261	EPSD	GDSC;CCLE	5.604	Up-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q6UB98	ANKRD12	O14757	CHEK1	S1085	S1079R	1079	Missense	distal	-6	no	8.603	8.523	EPSD	GDSC;CCLE	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q6UB98	ANKRD12	O14757	CHEK1	S1085	F1080C	1080	Missense	distal	-5	no	8.603	8.512	EPSD	GDSC;CCLE	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q6UB98	ANKRD12	O14757	CHEK1	S1143	E1137*	1137	Missense	distal	-6	no	14.270	14.615	EPSD	GDSC	5.604	Up-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q6UB98	ANKRD12	O14757	CHEK1	S1311	R1308*	1308	Missense	distal	-3	no	6.033	-40.914	EPSD	GDSC	5.604	Loss
CAMK_CAMKL_CHK1_CHEK1_ST	Q6UB98	ANKRD12	O14757	CHEK1	S1790	R1785Q	1785	Missense	distal	-5	no	9.650	9.254	EPSD	GDSC;CCLE	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q6UB98	ANKRD12	O14757	CHEK1	S1790	P1793R	1793	Missense	distal	3	no	9.650	9.318	EPSD	GDSC;CCLE	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q9H8N7	ZNF395	O14757	CHEK1	S66	P65T	65	Missense	proximal	-1	no	6.704	6.461	EPSD	GDSC;CCLE	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q9H8N7	ZNF395	O14757	CHEK1	S275	K271E	271	Missense	distal	-4	no	8.740	8.842	EPSD	GDSC;CCLE	5.604	Up-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q9H8N7	ZNF395	O14757	CHEK1	S447	R446Q	446	Missense	proximal	-1	no	8.186	8.202	PhosphoSitePlus	GDSC;CCLE	5.604	Up-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q9H8N7	ZNF395	O14757	CHEK1	S447	P442S	442	Missense	distal	-5	no	8.186	9.705	PhosphoSitePlus	GDSC;CCLE	5.604	Up-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q9H8N7	ZNF395	O14757	CHEK1	S449	R446Q	446	Missense	distal	-3	no	10.362	3.155	EPSD	GDSC;CCLE	5.604	Loss
CAMK_CAMKL_CHK1_CHEK1_ST	Q9H8N7	ZNF395	O14757	CHEK1	S449	P442S	442	Missense	distal	-7	no	10.362	11.032	EPSD	GDSC;CCLE	5.604	Up-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q9H8N7	ZNF395	O14757	CHEK1	S474	P470L	470	Missense	distal	-4	no	8.825	8.641	EPSD	GDSC;CCLE	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	P12956	XRCC6	O14757	CHEK1	T334	I327V	327	Missense	distal	-7	no	6.400	6.836	EPSD	GDSC;CCLE	5.604	Up-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	P12956	XRCC6	O14757	CHEK1	S520	S520F	520	Missense	central	0	yes	11.067	0.000	EPSD	GDSC;CCLE	5.604	Loss
CAMK_CAMKL_CHK1_CHEK1_ST	Q13257	MAD2L1	O14757	CHEK1	S130	E127K	127	Missense	distal	-3	no	2.415	5.678	EPSD	GDSC;CCLE	5.604	Gain
CAMK_CAMKL_CHK1_CHEK1_ST	Q13043	STK4	O14757	CHEK1	T360	T353A	353	Missense	distal	-7	no	4.335	5.652	EPSD	GDSC	5.604	Gain
CAMK_CAMKL_CHK1_CHEK1_ST	O75592	MYCBP2	O14757	CHEK1	S1176	A1183T	1183	Missense	distal	7	no	6.584	6.467	EPSD	GDSC;CCLE	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	O75592	MYCBP2	O14757	CHEK1	S1189	A1183T	1183	Missense	distal	-6	no	7.319	7.514	EPSD	GDSC;CCLE	5.604	Up-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	O75592	MYCBP2	O14757	CHEK1	S2445	P2447T	2447	Missense	proximal	2	no	8.657	8.342	EPSD	GDSC;CCLE	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	O75592	MYCBP2	O14757	CHEK1	S2445	G2440R	2440	Missense	distal	-5	no	8.657	8.822	EPSD	GDSC;CCLE	5.604	Up-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	O75592	MYCBP2	O14757	CHEK1	S2689	S2684P	2684	Missense	distal	-5	no	5.830	4.311	EPSD	GDSC;CCLE	5.604	Loss
CAMK_CAMKL_CHK1_CHEK1_ST	O75592	MYCBP2	O14757	CHEK1	S2745	L2750S	2750	Missense	distal	5	no	9.153	9.397	EPSD	GDSC	5.604	Up-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	O75592	MYCBP2	O14757	CHEK1	S2768	R2771*	2771	Missense	distal	3	no	10.948	9.514	EPSD	GDSC	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	O75592	MYCBP2	O14757	CHEK1	S2774	R2771*	2771	Missense	distal	-3	no	6.470	-40.476	EPSD	GDSC	5.604	Loss
CAMK_CAMKL_CHK1_CHEK1_ST	O75592	MYCBP2	O14757	CHEK1	S2831	D2825Y	2825	Missense	distal	-6	no	7.183	7.517	EPSD	GDSC;CCLE	5.604	Up-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	O75592	MYCBP2	O14757	CHEK1	S2858	T2859M	2859	Missense	proximal	1	no	6.461	6.440	EPSD	GDSC;CCLE	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	O75592	MYCBP2	O14757	CHEK1	S2860	T2859M	2859	Missense	proximal	-1	no	10.860	10.867	EPSD	GDSC;CCLE	5.604	Up-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	O75592	MYCBP2	O14757	CHEK1	S2865	T2859M	2859	Missense	distal	-6	no	5.740	5.733	EPSD	GDSC;CCLE	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	O75592	MYCBP2	O14757	CHEK1	S2865	D2869E	2869	Missense	distal	4	no	5.740	5.648	EPSD	GDSC;CCLE	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	O75592	MYCBP2	O14757	CHEK1	S2882	N2889K	2889	Missense	distal	7	no	6.114	6.052	EPSD	GDSC;CCLE	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	O75592	MYCBP2	O14757	CHEK1	S3481	L3487P	3487	Missense	distal	6	no	12.798	13.008	EPSD	GDSC;CCLE	5.604	Up-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	O75592	MYCBP2	O14757	CHEK1	S3489	L3487P	3487	Missense	proximal	-2	no	10.182	10.361	EPSD	GDSC;CCLE	5.604	Up-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	O75592	MYCBP2	O14757	CHEK1	S3758	R3765*	3765	Missense	distal	7	no	10.523	9.476	EPSD	GDSC	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q9BRD0	BUD13	O14757	CHEK1	S184	P190S	190	Missense	distal	6	no	11.487	10.868	EPSD	GDSC;CCLE	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q9BRD0	BUD13	O14757	CHEK1	S197	P190S	190	Missense	distal	-7	no	11.188	11.858	EPSD	GDSC;CCLE	5.604	Up-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q9BRD0	BUD13	O14757	CHEK1	T399	D405A	405	Missense	distal	6	no	7.950	8.522	EPSD	GDSC	5.604	Up-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q9BRD0	BUD13	O14757	CHEK1	S401	D405A	405	Missense	distal	4	no	11.927	12.071	EPSD	GDSC	5.604	Up-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	O60343	TBC1D4	O14757	CHEK1	S318	Q323P	323	Missense	distal	5	no	9.143	9.089	EPSD	GDSC;CCLE	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	O60343	TBC1D4	O14757	CHEK1	S341	R337W	337	Missense	distal	-4	no	7.708	6.946	EPSD	GDSC;CCLE	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	O60343	TBC1D4	O14757	CHEK1	S341	R336*	336	Missense	distal	-5	no	7.708	7.147	EPSD	GDSC	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	O60343	TBC1D4	O14757	CHEK1	S771	R769Q	769	Missense	proximal	-2	no	9.775	9.821	EPSD	GDSC;CCLE	5.604	Up-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	O60343	TBC1D4	O14757	CHEK1	S771	R769W	769	Missense	proximal	-2	no	9.775	9.896	EPSD	GDSC	5.604	Up-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	O60343	TBC1D4	O14757	CHEK1	S1207	S1207N	1207	Missense	central	0	yes	11.305	0.000	EPSD	GDSC;CCLE	5.604	Loss
CAMK_CAMKL_CHK1_CHEK1_ST	P36507	MAP2K2	O14757	CHEK1	S306	P301A	301	Missense	distal	-5	no	8.439	7.230	EPSD	GDSC;CCLE	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q9GZR7	DDX24	O14757	CHEK1	S82	Q79L	79	Missense	distal	-3	no	7.723	-3.617	PhosphoSitePlus	GDSC	5.604	Loss
CAMK_CAMKL_CHK1_CHEK1_ST	Q9GZR7	DDX24	O14757	CHEK1	S208	F212L	212	Missense	distal	4	no	8.739	8.677	EPSD	GDSC;CCLE	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q9GZR7	DDX24	O14757	CHEK1	T532	K531E	531	Missense	proximal	-1	no	5.746	5.804	EPSD	GDSC;CCLE	5.604	Up-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q14247	CTTN	O14757	CHEK1	S106	E103K	103	Missense	distal	-3	no	2.550	5.812	EPSD	GDSC;CCLE	5.604	Gain
CAMK_CAMKL_CHK1_CHEK1_ST	Q14247	CTTN	O14757	CHEK1	S113	V115A	115	Missense	proximal	2	no	11.869	12.432	EPSD	GDSC;CCLE	5.604	Up-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q14247	CTTN	O14757	CHEK1	S405	Q409K	409	Missense	distal	4	no	5.971	5.873	EPSD	GDSC;CCLE	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	P39748	FEN1	O14757	CHEK1	T195	L190V	190	Missense	distal	-5	no	12.080	8.603	PhosphoSitePlus	GDSC;CCLE	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	P39748	FEN1	O14757	CHEK1	S255	R261W	261	Missense	distal	6	no	8.229	8.696	EPSD	GDSC	5.604	Up-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	P39748	FEN1	O14757	CHEK1	S255	I259M	259	Missense	distal	4	no	8.229	8.288	EPSD	GDSC	5.604	Up-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	P39748	FEN1	O14757	CHEK1	S255	R262*	262	Missense	distal	7	no	8.229	7.183	EPSD	GDSC	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	P39748	FEN1	O14757	CHEK1	S335	S335N	335	Missense	central	0	yes	8.627	0.000	EPSD	GDSC;CCLE	5.604	Loss
CAMK_CAMKL_CHK1_CHEK1_ST	Q13263	TRIM28	O14757	CHEK1	S285	R282C	282	Missense	distal	-3	no	8.908	0.817	EPSD	GDSC;CCLE	5.604	Loss
CAMK_CAMKL_CHK1_CHEK1_ST	Q13263	TRIM28	O14757	CHEK1	T415	G414S	414	Missense	proximal	-1	no	5.657	5.479	EPSD	GDSC;CCLE	5.604	Loss
CAMK_CAMKL_CHK1_CHEK1_ST	Q13263	TRIM28	O14757	CHEK1	T415	T415I	415	Missense	central	0	yes	5.657	0.000	EPSD	GDSC;CCLE	5.604	Loss
CAMK_CAMKL_CHK1_CHEK1_ST	Q13263	TRIM28	O14757	CHEK1	S473	S471F	471	Missense	proximal	-2	no	8.214	8.504	PhosphoSitePlus	GDSC;CCLE	5.604	Up-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q13263	TRIM28	O14757	CHEK1	S594	S601L	601	Missense	distal	7	no	8.218	8.210	EPSD	GDSC;CCLE	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q13263	TRIM28	O14757	CHEK1	S752	S752*	752	Missense	central	0	yes	6.033	0.000	EPSD	GDSC	5.604	Loss
CAMK_CAMKL_CHK1_CHEK1_ST	Q13263	TRIM28	O14757	CHEK1	S756	S752*	752	Missense	distal	-4	no	8.323	7.425	EPSD	GDSC	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	P49792	RANBP2	O14757	CHEK1	S26	R23G	23	Missense	distal	-3	no	10.697	2.922	EPSD	GDSC;CCLE	5.604	Loss
CAMK_CAMKL_CHK1_CHEK1_ST	P49792	RANBP2	O14757	CHEK1	S313	R310*	310	Missense	distal	-3	no	7.683	-39.264	EPSD	GDSC	5.604	Loss
CAMK_CAMKL_CHK1_CHEK1_ST	P49792	RANBP2	O14757	CHEK1	S767	R769*	769	Missense	proximal	2	no	6.870	6.266	EPSD	GDSC	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	P49792	RANBP2	O14757	CHEK1	T1226	I1221L	1221	Missense	distal	-5	no	10.522	12.553	EPSD	GDSC;CCLE	5.604	Up-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	P49792	RANBP2	O14757	CHEK1	S1833	S1832P	1832	Missense	proximal	-1	no	6.053	6.500	EPSD	GDSC;CCLE	5.604	Up-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	P49792	RANBP2	O14757	CHEK1	S1955	F1961I	1961	Missense	distal	6	no	9.165	8.804	EPSD	GDSC;CCLE	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	P49792	RANBP2	O14757	CHEK1	S2766	T2768A	2768	Missense	proximal	2	no	4.914	5.762	EPSD	GDSC;CCLE	5.604	Gain
CAMK_CAMKL_CHK1_CHEK1_ST	Q9BQG0	MYBBP1A	O14757	CHEK1	T79	T79M	79	Missense	central	0	yes	8.017	0.000	EPSD	GDSC;CCLE	5.604	Loss
CAMK_CAMKL_CHK1_CHEK1_ST	Q9BQG0	MYBBP1A	O14757	CHEK1	T637	R634W	634	Missense	distal	-3	no	6.856	-26.747	EPSD	GDSC	5.604	Loss
CAMK_CAMKL_CHK1_CHEK1_ST	Q9BQG0	MYBBP1A	O14757	CHEK1	T637	R636H	636	Missense	proximal	-1	no	6.856	6.981	EPSD	GDSC;CCLE	5.604	Up-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q9BQG0	MYBBP1A	O14757	CHEK1	S775	N777K	777	Missense	proximal	2	no	8.939	9.348	EPSD	GDSC;CCLE	5.604	Up-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q9BQG0	MYBBP1A	O14757	CHEK1	S1243	T1239A	1239	Missense	distal	-4	no	8.906	9.336	EPSD	GDSC;CCLE	5.604	Up-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q9HC62	SENP2	O14757	CHEK1	S322	Y315C	315	Missense	distal	-7	no	5.083	5.753	EPSD	GDSC;CCLE	5.604	Gain
CAMK_CAMKL_CHK1_CHEK1_ST	Q08AD1	CAMSAP2	O14757	CHEK1	S86	R83H	83	Missense	distal	-3	no	9.242	3.433	EPSD	GDSC	5.604	Loss
CAMK_CAMKL_CHK1_CHEK1_ST	Q08AD1	CAMSAP2	O14757	CHEK1	T826	D827H	827	Missense	proximal	1	no	6.153	6.008	EPSD	GDSC;CCLE	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	P30305	CDC25B	O14757	CHEK1	S151	V154A	154	Missense	distal	3	no	9.075	8.830	EPSD	GDSC	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	P30305	CDC25B	O14757	CHEK1	S178	E179K	179	Missense	proximal	1	no	10.481	10.407	EPSD	GDSC	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	P30305	CDC25B	O14757	CHEK1	S182	E179K	179	Missense	distal	-3	no	3.727	6.990	EPSD	GDSC	5.604	Gain
CAMK_CAMKL_CHK1_CHEK1_ST	P30305	CDC25B	O14757	CHEK1	S375	R369C	369	Missense	distal	-6	no	9.149	9.265	EPSD	GDSC	5.604	Up-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q5JSZ5	PRRC2B	O14757	CHEK1	S104	T102M	102	Missense	proximal	-2	no	5.996	5.884	EPSD	GDSC;CCLE	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q5JSZ5	PRRC2B	O14757	CHEK1	S120	T126I	126	Missense	distal	6	no	8.802	8.534	EPSD	GDSC;CCLE	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q5JSZ5	PRRC2B	O14757	CHEK1	S480	D486Y	486	Missense	distal	6	no	7.562	8.487	EPSD	GDSC;CCLE	5.604	Up-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q5JSZ5	PRRC2B	O14757	CHEK1	S480	E485G	485	Missense	distal	5	no	7.562	7.285	EPSD	GDSC;CCLE	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q5JSZ5	PRRC2B	O14757	CHEK1	T1251	D1252N	1252	Missense	proximal	1	no	9.182	9.075	EPSD	GDSC;CCLE	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q5JSZ5	PRRC2B	O14757	CHEK1	S1470	E1473K	1473	Missense	distal	3	no	7.134	6.318	EPSD	GDSC	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q5JSZ5	PRRC2B	O14757	CHEK1	S1470	P1476R	1476	Missense	distal	6	no	7.134	6.602	EPSD	GDSC	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q5JSZ5	PRRC2B	O14757	CHEK1	S1858	L1852R	1852	Missense	distal	-6	no	6.978	6.874	EPSD	GDSC;CCLE	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q5JSZ5	PRRC2B	O14757	CHEK1	S2161	P2168A	2168	Missense	distal	7	no	9.690	9.684	EPSD	GDSC;CCLE	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q5JSZ5	PRRC2B	O14757	CHEK1	S2161	A2162S	2162	Missense	proximal	1	no	9.690	9.672	EPSD	GDSC;CCLE	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	P02545	LMNA	O14757	CHEK1	S75	E82V	82	Missense	distal	7	no	10.848	10.643	EPSD	GDSC	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	P02545	LMNA	O14757	CHEK1	S404	G411C	411	Missense	distal	7	no	7.892	7.480	EPSD	GDSC;CCLE	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	P02545	LMNA	O14757	CHEK1	S404	S403P	403	Missense	proximal	-1	no	7.892	8.339	EPSD	GDSC;CCLE	5.604	Up-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	P02545	LMNA	O14757	CHEK1	S657	S662I	662	Missense	distal	5	no	10.155	10.012	EPSD	GDSC;CCLE	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	P02545	LMNA	O14757	CHEK1	S657	N660I	660	Missense	distal	3	no	10.155	8.939	EPSD	GDSC;CCLE	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	O15151	MDM4	O14757	CHEK1	S127	I130F	130	Missense	distal	3	no	6.492	7.055	EPSD	GDSC;CCLE	5.604	Up-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	O15151	MDM4	O14757	CHEK1	S367	R363Q	363	Missense	distal	-4	no	8.466	8.626	EPSD;PhosphoSitePlus	GDSC;CCLE	5.604	Up-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	O95625	ZBTB11	O14757	CHEK1	T15	Y13S	13	Missense	proximal	-2	no	9.898	9.786	EPSD	GDSC	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q9UMR2	DDX19B	O14757	CHEK1	S93	R98W	98	Missense	distal	5	no	7.232	7.063	PhosphoSitePlus	GDSC;CCLE	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q9UMR2	DDX19B	O14757	CHEK1	S93	S90L	90	Missense	distal	-3	no	7.232	-1.619	PhosphoSitePlus	GDSC	5.604	Loss
CAMK_CAMKL_CHK1_CHEK1_ST	Q9UMR2	DDX19B	O14757	CHEK1	S93	S93Y	93	Missense	central	0	yes	7.232	0.000	PhosphoSitePlus	GDSC	5.604	Loss
CAMK_CAMKL_CHK1_CHEK1_ST	Q9UMR2	DDX19B	O14757	CHEK1	S347	A346G	346	Missense	proximal	-1	no	7.002	6.848	EPSD	GDSC;CCLE	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q92974	ARHGEF2	O14757	CHEK1	S142	R141H	141	Missense	proximal	-1	no	6.650	6.776	EPSD	GDSC	5.604	Up-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q9Y570	PPME1	O14757	CHEK1	S15	R12C	12	Missense	distal	-3	no	13.534	5.443	PhosphoSitePlus	GDSC	5.604	Loss
CAMK_CAMKL_CHK1_CHEK1_ST	Q9Y570	PPME1	O14757	CHEK1	S42	P35H	35	Missense	distal	-7	no	9.468	9.819	EPSD	GDSC	5.604	Up-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q9Y570	PPME1	O14757	CHEK1	S306	R303*	303	Missense	distal	-3	no	8.610	-38.337	EPSD	GDSC	5.604	Loss
CAMK_CAMKL_CHK1_CHEK1_ST	Q9Y570	PPME1	O14757	CHEK1	S306	L310V	310	Missense	distal	4	no	8.610	8.685	EPSD	GDSC;CCLE	5.604	Up-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	P27816	MAP4	O14757	CHEK1	S253	T248I	248	Missense	distal	-5	no	7.271	7.296	EPSD	GDSC	5.604	Up-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	P27816	MAP4	O14757	CHEK1	T451	A447S	447	Missense	distal	-4	no	9.226	8.846	EPSD	GDSC;CCLE	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	P27816	MAP4	O14757	CHEK1	S602	S602N	602	Missense	central	0	yes	8.609	0.000	EPSD	GDSC	5.604	Loss
CAMK_CAMKL_CHK1_CHEK1_ST	P27816	MAP4	O14757	CHEK1	S801	S803G	803	Missense	proximal	2	no	6.145	6.080	EPSD	GDSC;CCLE	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	P27816	MAP4	O14757	CHEK1	S801	A808V	808	Missense	distal	7	no	6.145	6.224	EPSD	GDSC;CCLE	5.604	Up-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	P27816	MAP4	O14757	CHEK1	T900	P902L	902	Missense	proximal	2	no	5.698	5.381	EPSD	GDSC	5.604	Loss
CAMK_CAMKL_CHK1_CHEK1_ST	P27816	MAP4	O14757	CHEK1	T909	P902L	902	Missense	distal	-7	no	7.205	6.991	EPSD	GDSC	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	O43395	PRPF3	O14757	CHEK1	S174	P170T	170	Missense	distal	-4	no	8.206	7.919	EPSD	GDSC	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	O43395	PRPF3	O14757	CHEK1	S552	K556N	556	Missense	distal	4	no	7.654	7.721	EPSD	GDSC;CCLE	5.604	Up-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	O43395	PRPF3	O14757	CHEK1	S552	R549*	549	Missense	distal	-3	no	7.654	-39.293	EPSD	GDSC	5.604	Loss
CAMK_CAMKL_CHK1_CHEK1_ST	Q00341	HDLBP	O14757	CHEK1	T757	R754H	754	Missense	distal	-3	no	9.881	4.072	EPSD	GDSC;CCLE	5.604	Loss
CAMK_CAMKL_CHK1_CHEK1_ST	Q00341	HDLBP	O14757	CHEK1	T842	G841S	841	Missense	proximal	-1	no	9.276	9.098	EPSD	GDSC;CCLE	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q86WR7	PROSER2	O14757	CHEK1	S179	P180A	180	Missense	proximal	1	no	7.143	7.198	EPSD	GDSC	5.604	Up-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q14004	CDK13	O14757	CHEK1	S397	S395C	395	Missense	proximal	-2	no	8.338	8.385	EPSD	GDSC;CCLE	5.604	Up-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q14004	CDK13	O14757	CHEK1	T1058	S1065F	1065	Missense	distal	7	no	7.433	7.003	EPSD	GDSC	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q14004	CDK13	O14757	CHEK1	T1271	E1266K	1266	Missense	distal	-5	no	3.165	5.727	EPSD	GDSC;CCLE	5.604	Gain
CAMK_CAMKL_CHK1_CHEK1_ST	Q6T4R5	NHS	O14757	CHEK1	S471	G469V	469	Missense	proximal	-2	no	5.591	5.649	EPSD	GDSC;CCLE	5.604	Gain
CAMK_CAMKL_CHK1_CHEK1_ST	Q6T4R5	NHS	O14757	CHEK1	S1530	S1535T	1535	Missense	distal	5	no	8.239	8.017	EPSD	GDSC	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q5JTH9	RRP12	O14757	CHEK1	S180	R177H	177	Missense	distal	-3	no	10.028	4.219	EPSD	GDSC	5.604	Loss
CAMK_CAMKL_CHK1_CHEK1_ST	Q5JTH9	RRP12	O14757	CHEK1	S829	T828P	828	Missense	proximal	-1	no	6.515	6.757	EPSD	GDSC	5.604	Up-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q5JTH9	RRP12	O14757	CHEK1	S829	P835S	835	Missense	distal	6	no	6.515	5.895	EPSD	GDSC	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q9HAW4	CLSPN	O14757	CHEK1	S341	E346*	346	Missense	distal	5	no	5.730	5.246	EPSD	GDSC	5.604	Loss
CAMK_CAMKL_CHK1_CHEK1_ST	Q9HAW4	CLSPN	O14757	CHEK1	S798	G805R	805	Missense	distal	7	no	7.299	7.294	EPSD	GDSC	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q9HAW4	CLSPN	O14757	CHEK1	S810	G805R	805	Missense	distal	-5	no	7.595	7.760	EPSD	GDSC	5.604	Up-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q9HAW4	CLSPN	O14757	CHEK1	S1223	R1224L	1224	Missense	proximal	1	no	9.247	9.212	EPSD	GDSC	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q9HAW4	CLSPN	O14757	CHEK1	S1246	A1241V	1241	Missense	distal	-5	no	7.155	9.595	EPSD	GDSC	5.604	Up-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q14738	PPP2R5D	O14757	CHEK1	S88	R91C	91	Missense	distal	3	no	8.975	8.028	EPSD	GDSC;CCLE	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q14738	PPP2R5D	O14757	CHEK1	S89	R91C	91	Missense	proximal	2	no	7.439	7.173	EPSD	GDSC;CCLE	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	P15822	HIVEP1	O14757	CHEK1	S698	S698N	698	Missense	central	0	yes	7.030	0.000	EPSD	GDSC;CCLE	5.604	Loss
CAMK_CAMKL_CHK1_CHEK1_ST	P15822	HIVEP1	O14757	CHEK1	S1147	E1152K	1152	Missense	distal	5	no	12.535	12.470	EPSD	GDSC;CCLE	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	P15822	HIVEP1	O14757	CHEK1	S1368	R1361Q	1361	Missense	distal	-7	no	9.521	9.779	EPSD	GDSC;CCLE	5.604	Up-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	P15822	HIVEP1	O14757	CHEK1	S1749	S1744N	1744	Missense	distal	-5	no	10.716	11.209	PhosphoSitePlus	GDSC	5.604	Up-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	P15822	HIVEP1	O14757	CHEK1	S2273	P2274S	2274	Missense	proximal	1	no	7.067	7.104	EPSD	GDSC;CCLE	5.604	Up-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	P15822	HIVEP1	O14757	CHEK1	S2273	P2274L	2274	Missense	proximal	1	no	7.067	7.095	EPSD	GDSC;CCLE	5.604	Up-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	P15822	HIVEP1	O14757	CHEK1	T2699	P2694L	2694	Missense	distal	-5	no	6.307	11.014	EPSD	GDSC	5.604	Up-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q53F19	NCBP3	O14757	CHEK1	S193	A198V	198	Missense	distal	5	no	11.703	11.599	EPSD	GDSC	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q53F19	NCBP3	O14757	CHEK1	S210	E207K	207	Missense	distal	-3	no	3.792	7.055	EPSD	GDSC	5.604	Gain
CAMK_CAMKL_CHK1_CHEK1_ST	Q53F19	NCBP3	O14757	CHEK1	S387	A388V	388	Missense	proximal	1	no	7.910	7.885	EPSD	GDSC	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q53F19	NCBP3	O14757	CHEK1	S389	A388V	388	Missense	proximal	-1	no	7.654	7.576	EPSD	GDSC	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q53F19	NCBP3	O14757	CHEK1	S393	A388V	388	Missense	distal	-5	no	5.145	7.584	EPSD	GDSC	5.604	Gain
CAMK_CAMKL_CHK1_CHEK1_ST	Q53F19	NCBP3	O14757	CHEK1	S444	S444G	444	Missense	central	0	yes	9.003	0.000	EPSD	GDSC	5.604	Loss
CAMK_CAMKL_CHK1_CHEK1_ST	Q53F19	NCBP3	O14757	CHEK1	S530	G524C	524	Missense	distal	-6	no	5.879	5.877	EPSD	GDSC	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q9HB96	FANCE	O14757	CHEK1	S180	G174E	174	Missense	distal	-6	no	9.078	8.918	EPSD	GDSC;CCLE	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q9HB96	FANCE	O14757	CHEK1	S204	S204L	204	Missense	central	0	yes	8.434	0.000	EPSD	GDSC	5.604	Loss
CAMK_CAMKL_CHK1_CHEK1_ST	Q9HB96	FANCE	O14757	CHEK1	S204	R201I	201	Missense	distal	-3	no	8.434	-0.324	EPSD	GDSC	5.604	Loss
CAMK_CAMKL_CHK1_CHEK1_ST	Q9HB96	FANCE	O14757	CHEK1	T346	G340R	340	Missense	distal	-6	no	9.035	8.918	PhosphoSitePlus;EPSD	GDSC	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q9HB96	FANCE	O14757	CHEK1	S374	R371Q	371	Missense	distal	-3	no	14.596	7.389	EPSD;PhosphoSitePlus	GDSC	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	P06493	CDK1	O14757	CHEK1	T25	V30L	30	Missense	distal	5	no	10.871	10.712	EPSD	GDSC	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	P06493	CDK1	O14757	CHEK1	T183	S178L	178	Missense	distal	-5	no	7.979	11.167	EPSD	GDSC;CCLE	5.604	Up-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q9BY77	POLDIP3	O14757	CHEK1	S375	S368C	368	Missense	distal	-7	no	6.093	5.106	EPSD	GDSC	5.604	Loss
CAMK_CAMKL_CHK1_CHEK1_ST	P18858	LIG1	O14757	CHEK1	S419	I424T	424	Missense	distal	5	no	7.217	7.138	EPSD	GDSC	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	P18858	LIG1	O14757	CHEK1	S419	L414R	414	Missense	distal	-5	no	7.217	4.241	EPSD	GDSC	5.604	Loss
CAMK_CAMKL_CHK1_CHEK1_ST	P18858	LIG1	O14757	CHEK1	S447	A443T	443	Missense	distal	-4	no	8.545	8.115	EPSD	GDSC	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	P18858	LIG1	O14757	CHEK1	S552	R549W	549	Missense	distal	-3	no	7.927	-25.676	EPSD	GDSC;CCLE	5.604	Loss
CAMK_CAMKL_CHK1_CHEK1_ST	P18858	LIG1	O14757	CHEK1	S901	Q906R	906	Missense	distal	5	no	14.400	14.324	EPSD	GDSC;CCLE	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	P43405	SYK	O14757	CHEK1	T256	I262L	262	Missense	distal	6	no	8.766	9.133	EPSD	GDSC	5.604	Up-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	P43405	SYK	O14757	CHEK1	S316	E315K	315	Missense	proximal	-1	no	8.686	8.628	EPSD	GDSC;CCLE	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	P52294	KPNA1	O14757	CHEK1	S13	K12Q	12	Missense	proximal	-1	no	10.253	10.417	EPSD	GDSC	5.604	Up-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q8N4C8	MINK1	O14757	CHEK1	S749	A753T	753	Missense	distal	4	no	8.314	8.132	EPSD	GDSC;CCLE	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q8N4C8	MINK1	O14757	CHEK1	S993	D988N	988	Missense	distal	-5	no	10.038	11.306	EPSD	GDSC	5.604	Up-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	P30307	CDC25C	O14757	CHEK1	S38	E34Q	34	Missense	distal	-4	no	10.974	10.931	EPSD	GDSC;CCLE	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	P30307	CDC25C	O14757	CHEK1	S147	K140E	140	Missense	distal	-7	no	7.791	7.093	EPSD	GDSC;CCLE	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	P30307	CDC25C	O14757	CHEK1	S247	G248D	248	Missense	proximal	1	no	8.170	8.257	EPSD	GDSC	5.604	Up-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	P30307	CDC25C	O14757	CHEK1	S451	R458Q	458	Missense	distal	7	no	6.936	7.091	EPSD	GDSC;CCLE	5.604	Up-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	P06400	RB1	O14757	CHEK1	S83	S82*	82	Missense	proximal	-1	no	6.116	6.463	EPSD	GDSC	5.604	Up-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	P06400	RB1	O14757	CHEK1	S83	W78*	78	Missense	distal	-5	no	6.116	6.414	EPSD	GDSC	5.604	Up-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	P06400	RB1	O14757	CHEK1	S163	E166*	166	Missense	distal	3	no	7.685	4.788	EPSD	GDSC	5.604	Loss
CAMK_CAMKL_CHK1_CHEK1_ST	Q96ST3	SIN3A	O14757	CHEK1	T432	R429*	429	Missense	distal	-3	no	9.233	-37.714	EPSD	GDSC	5.604	Loss
CAMK_CAMKL_CHK1_CHEK1_ST	Q96ST3	SIN3A	O14757	CHEK1	S641	A645P	645	Missense	distal	4	no	6.078	6.024	EPSD	GDSC;CCLE	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q96ST3	SIN3A	O14757	CHEK1	S641	E647K	647	Missense	distal	6	no	6.078	6.348	EPSD	GDSC;CCLE	5.604	Up-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q96ST3	SIN3A	O14757	CHEK1	S755	E759*	759	Missense	distal	4	no	5.642	5.868	EPSD	GDSC	5.604	Up-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q96ST3	SIN3A	O14757	CHEK1	S864	P861R	861	Missense	distal	-3	no	-0.001	7.135	EPSD	GDSC	5.604	Gain
CAMK_CAMKL_CHK1_CHEK1_ST	Q96ST3	SIN3A	O14757	CHEK1	S911	L904P	904	Missense	distal	-7	no	13.347	13.562	EPSD	GDSC;CCLE	5.604	Up-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q96ST3	SIN3A	O14757	CHEK1	S911	A913V	913	Missense	proximal	2	no	13.347	12.784	EPSD	GDSC;CCLE	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q32P44	EML3	O14757	CHEK1	S156	S163*	163	Missense	distal	7	no	9.006	8.052	EPSD	GDSC	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q32P44	EML3	O14757	CHEK1	S157	S163*	163	Missense	distal	6	no	7.989	8.762	EPSD	GDSC	5.604	Up-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q32P44	EML3	O14757	CHEK1	S490	S488R	488	Missense	proximal	-2	no	9.058	9.157	EPSD	GDSC;CCLE	5.604	Up-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q32P44	EML3	O14757	CHEK1	S887	P886L	886	Missense	proximal	-1	no	8.202	8.016	EPSD	GDSC;CCLE	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q32P44	EML3	O14757	CHEK1	S887	P886S	886	Missense	proximal	-1	no	8.202	7.755	EPSD	GDSC;CCLE	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q9Y4F5	CEP170B	O14757	CHEK1	S224	F226L	226	Missense	proximal	2	no	10.436	10.186	EPSD	GDSC	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q9Y4F5	CEP170B	O14757	CHEK1	S224	R220W	220	Missense	distal	-4	no	10.436	9.674	EPSD	GDSC	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q9Y4F5	CEP170B	O14757	CHEK1	S371	A370S	370	Missense	proximal	-1	no	8.771	8.438	EPSD	GDSC	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q9Y4F5	CEP170B	O14757	CHEK1	S371	K368E	368	Missense	distal	-3	no	8.771	5.508	EPSD	GDSC	5.604	Loss
CAMK_CAMKL_CHK1_CHEK1_ST	Q9Y4F5	CEP170B	O14757	CHEK1	T793	G790R	790	Missense	distal	-3	no	-1.481	6.294	EPSD	GDSC	5.604	Gain
CAMK_CAMKL_CHK1_CHEK1_ST	Q9Y4F5	CEP170B	O14757	CHEK1	S930	S930F	930	Missense	central	0	yes	7.980	0.000	EPSD	GDSC;CCLE	5.604	Loss
CAMK_CAMKL_CHK1_CHEK1_ST	Q9Y4F5	CEP170B	O14757	CHEK1	S930	A923G	923	Missense	distal	-7	no	7.980	7.309	EPSD	GDSC;CCLE	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q9Y4F5	CEP170B	O14757	CHEK1	S1114	T1117I	1117	Missense	distal	3	no	12.353	12.122	EPSD	GDSC	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q8WWI1	LMO7	O14757	CHEK1	S56	I60T	60	Missense	distal	4	no	10.722	10.682	EPSD	GDSC;CCLE	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q8WWI1	LMO7	O14757	CHEK1	S246	R239M	239	Missense	distal	-7	no	8.531	8.390	EPSD	GDSC	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q8WWI1	LMO7	O14757	CHEK1	S392	I393M	393	Missense	proximal	1	no	8.963	8.985	EPSD	GDSC	5.604	Up-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q8WWI1	LMO7	O14757	CHEK1	T1216	P1213R	1213	Missense	distal	-3	no	0.445	7.582	EPSD	GDSC	5.604	Gain
CMGC_MAPK_ERK1_MAPK3_ST	P11388	TOP2A	P27361	MAPK3	S230	L231P	231	Missense	proximal	1	no	4.643	13.681	EPSD	GDSC;CCLE	9.358	Gain
CMGC_MAPK_ERK1_MAPK3_ST	P11388	TOP2A	P27361	MAPK3	T950	L944S	944	Missense	distal	-6	no	16.507	16.838	EPSD	GDSC;CCLE	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P11388	TOP2A	P27361	MAPK3	S1213	G1216C	1216	Missense	distal	3	no	14.675	14.604	EPSD;PhosphoSitePlus	GDSC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P11388	TOP2A	P27361	MAPK3	S1354	S1361F	1361	Missense	distal	7	no	16.824	17.315	EPSD;PhosphoSitePlus	GDSC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P11388	TOP2A	P27361	MAPK3	T1360	S1361F	1361	Missense	proximal	1	no	7.362	10.202	EPSD	GDSC	9.358	Gain
CMGC_MAPK_ERK1_MAPK3_ST	P11388	TOP2A	P27361	MAPK3	S1361	S1361F	1361	Missense	central	0	yes	15.263	0.000	PhosphoSitePlus;EPSD	GDSC	9.358	Loss
CMGC_MAPK_ERK1_MAPK3_ST	P11388	TOP2A	P27361	MAPK3	S1393	S1392*	1392	Missense	proximal	-1	no	15.613	15.341	EPSD;PhosphoSitePlus	GDSC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P11388	TOP2A	P27361	MAPK3	T1427	S1428P	1428	Missense	proximal	1	no	5.747	14.801	EPSD	GDSC;CCLE	9.358	Gain
CMGC_MAPK_ERK1_MAPK3_ST	Q07820	MCL1	P27361	MAPK3	S121	M120V	120	Missense	proximal	-1	no	14.022	14.094	EPSD	GDSC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P15056	BRAF	P27361	MAPK3	S151	R146Q	146	Missense	distal	-5	no	14.464	14.457	EPSD	GDSC;CCLE	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P15056	BRAF	P27361	MAPK3	S317	A320S	320	Missense	distal	3	no	15.604	15.648	EPSD	GDSC;CCLE	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P15056	BRAF	P27361	MAPK3	S319	A320S	320	Missense	proximal	1	no	11.603	11.789	EPSD	GDSC;CCLE	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P15056	BRAF	P27361	MAPK3	T401	A400V	400	Missense	proximal	-1	no	15.379	15.429	PhosphoSitePlus;EPSD	GDSC;CCLE	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P15056	BRAF	P27361	MAPK3	S750	A747V	747	Missense	distal	-3	no	17.108	17.128	EPSD	GDSC;CCLE	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P15056	BRAF	P27361	MAPK3	T753	A747V	747	Missense	distal	-6	no	19.962	19.948	EPSD;PhosphoSitePlus	GDSC;CCLE	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P15056	BRAF	P27361	MAPK3	T753	G759*	759	Missense	distal	6	no	19.962	19.260	EPSD;PhosphoSitePlus	GDSC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P04626	ERBB2	P27361	MAPK3	S1151	P1149S	1149	Missense	proximal	-2	no	17.420	16.344	EPSD	GDSC;CCLE	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P10636	MAPT	P27361	MAPK3	S46	Q49H	49	Missense	distal	3	no	15.672	15.680	EPSD;PhosphoSitePlus	GDSC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P10636	MAPT	P27361	MAPK3	S46	A41V	41	Missense	distal	-5	no	15.672	15.695	EPSD;PhosphoSitePlus	GDSC;CCLE	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P10636	MAPT	P27361	MAPK3	T50	Q49H	49	Missense	proximal	-1	no	16.613	16.654	EPSD;PhosphoSitePlus	GDSC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P10636	MAPT	P27361	MAPK3	S228	R222H	222	Missense	distal	-6	no	17.196	17.191	EPSD	GDSC;CCLE	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P10636	MAPT	P27361	MAPK3	T470	A475V	475	Missense	distal	5	no	14.131	14.119	EPSD	GDSC;CCLE	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P10636	MAPT	P27361	MAPK3	S739	S739C	739	Missense	central	0	yes	19.967	0.000	EPSD	GDSC	9.358	Loss
CMGC_MAPK_ERK1_MAPK3_ST	P10636	MAPT	P27361	MAPK3	T744	S739C	739	Missense	distal	-5	no	9.660	9.498	EPSD	GDSC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q13541	EIF4EBP1	P27361	MAPK3	S65	P66T	66	Missense	proximal	1	no	14.573	5.696	PhosphoSitePlus	GDSC	9.358	Loss
CMGC_MAPK_ERK1_MAPK3_ST	Q13541	EIF4EBP1	P27361	MAPK3	T70	P66T	66	Missense	distal	-4	no	16.526	16.495	EPSD	GDSC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q13541	EIF4EBP1	P27361	MAPK3	S101	G108S	108	Missense	distal	7	no	17.868	17.728	EPSD	GDSC;CCLE	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q13541	EIF4EBP1	P27361	MAPK3	S112	G108S	108	Missense	distal	-4	no	10.620	10.658	EPSD	GDSC;CCLE	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q16828	DUSP6	P27361	MAPK3	S197	S202R	202	Missense	distal	5	no	17.628	17.484	EPSD;PhosphoSitePlus	GDSC;CCLE	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q16828	DUSP6	P27361	MAPK3	S205	S202R	202	Missense	distal	-3	no	9.420	9.382	EPSD	GDSC;CCLE	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P41235	HNF4A	P27361	MAPK3	S142	R136W	136	Missense	distal	-6	no	9.379	8.856	EPSD;PhosphoSitePlus	GDSC	9.358	Loss
CMGC_MAPK_ERK1_MAPK3_ST	P41235	HNF4A	P27361	MAPK3	S167	N173D	173	Missense	distal	6	no	14.115	14.167	EPSD;PhosphoSitePlus	GDSC;CCLE	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P41235	HNF4A	P27361	MAPK3	S378	A385V	385	Missense	distal	7	no	16.130	16.103	EPSD	GDSC;CCLE	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P41235	HNF4A	P27361	MAPK3	S378	P379H	379	Missense	proximal	1	no	16.130	8.375	EPSD	GDSC;CCLE	9.358	Loss
CMGC_MAPK_ERK1_MAPK3_ST	P41235	HNF4A	P27361	MAPK3	T455	G451R	451	Missense	distal	-4	no	9.549	9.510	EPSD	GDSC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P41235	HNF4A	P27361	MAPK3	T455	G451E	451	Missense	distal	-4	no	9.549	9.563	EPSD	GDSC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P41235	HNF4A	P27361	MAPK3	S461	I463V	463	Missense	proximal	2	no	10.418	10.428	EPSD;PhosphoSitePlus	GDSC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P41235	HNF4A	P27361	MAPK3	S461	I463T	463	Missense	proximal	2	no	10.418	10.442	EPSD;PhosphoSitePlus	GDSC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P41235	HNF4A	P27361	MAPK3	S461	P466L	466	Missense	distal	5	no	10.418	10.190	EPSD;PhosphoSitePlus	GDSC;CCLE	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q9NYV6	RRN3	P27361	MAPK3	S44	F41I	41	Missense	distal	-3	no	15.208	15.238	EPSD	GDSC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q9NYV6	RRN3	P27361	MAPK3	S172	D176N	176	Missense	distal	4	no	10.486	10.460	EPSD	GDSC;CCLE	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q9NYV6	RRN3	P27361	MAPK3	T200	W202L	202	Missense	proximal	2	no	16.458	16.507	EPSD	GDSC;CCLE	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q9NYV6	RRN3	P27361	MAPK3	S409	A412V	412	Missense	distal	3	no	10.269	10.275	EPSD	GDSC;CCLE	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q9NYV6	RRN3	P27361	MAPK3	T623	P624Q	624	Missense	proximal	1	no	16.050	8.106	EPSD	GDSC;CCLE	9.358	Loss
CMGC_MAPK_ERK1_MAPK3_ST	Q9NYV6	RRN3	P27361	MAPK3	S625	P624Q	624	Missense	proximal	-1	no	9.466	9.380	EPSD	GDSC;CCLE	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q9NYV6	RRN3	P27361	MAPK3	S626	P624Q	624	Missense	proximal	-2	no	12.891	11.127	EPSD	GDSC;CCLE	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P49790	NUP153	P27361	MAPK3	T102	A106T	106	Missense	distal	4	no	13.795	14.013	EPSD	GDSC;CCLE	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P49790	NUP153	P27361	MAPK3	S320	K317N	317	Missense	distal	-3	no	17.303	17.310	EPSD;PhosphoSitePlus	GDSC;CCLE	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P49790	NUP153	P27361	MAPK3	T413	E409G	409	Missense	distal	-4	no	14.096	14.082	EPSD;PhosphoSitePlus	GDSC;CCLE	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P49790	NUP153	P27361	MAPK3	T486	S481N	481	Missense	distal	-5	no	10.174	10.134	EPSD	GDSC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P49790	NUP153	P27361	MAPK3	S500	A507V	507	Missense	distal	7	no	16.603	16.575	EPSD	GDSC;CCLE	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P49790	NUP153	P27361	MAPK3	S614	D610A	610	Missense	distal	-4	no	15.797	15.700	EPSD	GDSC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P49790	NUP153	P27361	MAPK3	S687	A680T	680	Missense	distal	-7	no	13.863	13.790	EPSD	GDSC;CCLE	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P49790	NUP153	P27361	MAPK3	T747	C742Y	742	Missense	distal	-5	no	13.833	13.931	EPSD	GDSC;CCLE	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P49790	NUP153	P27361	MAPK3	T747	V754M	754	Missense	distal	7	no	13.833	13.965	EPSD	GDSC;CCLE	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P49790	NUP153	P27361	MAPK3	T996	S994C	994	Missense	proximal	-2	no	13.637	11.197	EPSD	GDSC;CCLE	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P49790	NUP153	P27361	MAPK3	T1032	T1032I	1032	Missense	central	0	yes	14.509	0.000	EPSD	GDSC;CCLE	9.358	Loss
CMGC_MAPK_ERK1_MAPK3_ST	P49790	NUP153	P27361	MAPK3	T1032	I1039M	1039	Missense	distal	7	no	14.509	14.560	EPSD	GDSC;CCLE	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P04049	RAF1	P27361	MAPK3	S25	G24S	24	Missense	proximal	-1	no	10.015	10.081	EPSD	GDSC;CCLE	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P04049	RAF1	P27361	MAPK3	S29	G24S	24	Missense	distal	-5	no	15.915	15.958	EPSD	GDSC;CCLE	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P04049	RAF1	P27361	MAPK3	S252	Q253P	253	Missense	proximal	1	no	8.636	16.580	EPSD	GDSC	9.358	Gain
CMGC_MAPK_ERK1_MAPK3_ST	P04049	RAF1	P27361	MAPK3	T260	Q253P	253	Missense	distal	-7	no	13.506	13.462	EPSD	GDSC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P04049	RAF1	P27361	MAPK3	S339	E343G	343	Missense	distal	4	no	10.322	10.262	EPSD	GDSC;CCLE	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P04049	RAF1	P27361	MAPK3	S359	S352F	352	Missense	distal	-7	no	9.764	9.983	EPSD	GDSC;CCLE	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P04049	RAF1	P27361	MAPK3	S624	A629S	629	Missense	distal	5	no	9.147	9.403	EPSD	GDSC;CCLE	9.358	Gain
CMGC_MAPK_ERK1_MAPK3_ST	Q16690	DUSP5	P27361	MAPK3	T321	T321M	321	Missense	central	0	yes	16.427	0.000	EPSD;PhosphoSitePlus	GDSC;CCLE	9.358	Loss
CMGC_MAPK_ERK1_MAPK3_ST	P15336	ATF2	P27361	MAPK3	T69	V63A	63	Missense	distal	-6	no	14.813	14.826	PhosphoSitePlus;EPSD	GDSC;CCLE	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P15336	ATF2	P27361	MAPK3	S136	Q134H	134	Missense	proximal	-2	no	16.279	16.816	EPSD	GDSC;CCLE	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P15336	ATF2	P27361	MAPK3	T325	H331L	331	Missense	distal	6	no	14.306	14.172	EPSD	GDSC;CCLE	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P15336	ATF2	P27361	MAPK3	S328	H331L	331	Missense	distal	3	no	17.676	17.658	EPSD	GDSC;CCLE	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P15336	ATF2	P27361	MAPK3	T333	H331L	331	Missense	proximal	-2	no	15.687	15.530	EPSD	GDSC;CCLE	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P49023	PXN	P27361	MAPK3	S85	S83F	83	Missense	proximal	-2	no	15.864	14.564	EPSD	GDSC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P49023	PXN	P27361	MAPK3	S85	V87E	87	Missense	proximal	2	no	15.864	15.881	EPSD	GDSC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P49023	PXN	P27361	MAPK3	S130	P129L	129	Missense	proximal	-1	no	15.799	15.704	EPSD;PhosphoSitePlus	GDSC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P49023	PXN	P27361	MAPK3	S188	G191R	191	Missense	distal	3	no	16.817	16.810	EPSD	GDSC;CCLE	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P49023	PXN	P27361	MAPK3	S188	S188R	188	Missense	central	0	yes	16.817	0.000	EPSD	GDSC	9.358	Loss
CMGC_MAPK_ERK1_MAPK3_ST	P49023	PXN	P27361	MAPK3	S303	R301G	301	Missense	proximal	-2	no	16.789	16.073	EPSD	GDSC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P49023	PXN	P27361	MAPK3	S303	S302G	302	Missense	proximal	-1	no	16.789	16.723	EPSD	GDSC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P49023	PXN	P27361	MAPK3	S303	G305R	305	Missense	proximal	2	no	16.789	16.794	EPSD	GDSC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P49023	PXN	P27361	MAPK3	S320	S321N	321	Missense	proximal	1	no	10.939	5.904	EPSD	GDSC;CCLE	9.358	Loss
CMGC_MAPK_ERK1_MAPK3_ST	P49023	PXN	P27361	MAPK3	S322	S321N	321	Missense	proximal	-1	no	17.609	17.560	EPSD	GDSC;CCLE	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P49023	PXN	P27361	MAPK3	S332	G331R	331	Missense	proximal	-1	no	10.497	10.521	EPSD	GDSC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P14618	PKM	P27361	MAPK3	S243	S249F	249	Missense	distal	6	no	10.490	9.777	EPSD	GDSC;CCLE	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P14618	PKM	P27361	MAPK3	S243	D250V	250	Missense	distal	7	no	10.490	10.702	EPSD	GDSC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P56270	MAZ	P27361	MAPK3	S323	R327C	327	Missense	distal	4	no	10.768	10.411	EPSD	GDSC;CCLE	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P56270	MAZ	P27361	MAPK3	S468	Q470*	470	Missense	proximal	2	no	12.051	11.994	EPSD	GDSC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P56270	MAZ	P27361	MAPK3	S469	Q470*	470	Missense	proximal	1	no	12.228	-9.882	EPSD	GDSC	9.358	Loss
CMGC_MAPK_ERK1_MAPK3_ST	P56270	MAZ	P27361	MAPK3	S474	Q470*	470	Missense	distal	-4	no	11.715	11.484	EPSD	GDSC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q9BUB5	MKNK1	P27361	MAPK3	S460	T463I	463	Missense	distal	3	no	19.168	19.130	EPSD	GDSC;CCLE	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q9BUB5	MKNK1	P27361	MAPK3	S460	R455H	455	Missense	distal	-5	no	19.168	19.177	EPSD	GDSC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q9UJY1	HSPB8	P27361	MAPK3	T87	E84*	84	Missense	distal	-3	no	14.689	14.489	EPSD;PhosphoSitePlus	GDSC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q9UJY1	HSPB8	P27361	MAPK3	T87	P88S	88	Missense	proximal	1	no	14.689	5.635	EPSD;PhosphoSitePlus	GDSC;CCLE	9.358	Loss
CMGC_MAPK_ERK1_MAPK3_ST	Q05682	CALD1	P27361	MAPK3	S480	D483V	483	Missense	distal	3	no	10.179	10.152	EPSD	GDSC;CCLE	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q05682	CALD1	P27361	MAPK3	T753	N757S	757	Missense	distal	4	no	14.328	14.475	EPSD	GDSC;CCLE	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q05682	CALD1	P27361	MAPK3	S759	P764L	764	Missense	distal	5	no	13.838	13.610	PhosphoSitePlus;EPSD	GDSC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q05682	CALD1	P27361	MAPK3	S759	S765T	765	Missense	distal	6	no	13.838	13.683	PhosphoSitePlus;EPSD	GDSC;CCLE	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q05682	CALD1	P27361	MAPK3	S759	N757S	757	Missense	proximal	-2	no	13.838	14.783	PhosphoSitePlus;EPSD	GDSC;CCLE	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q05682	CALD1	P27361	MAPK3	S789	T791A	791	Missense	proximal	2	no	18.446	18.419	EPSD;PhosphoSitePlus	GDSC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P38936	CDKN1A	P27361	MAPK3	T57	E56*	56	Missense	proximal	-1	no	13.226	12.979	EPSD	GDSC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P38936	CDKN1A	P27361	MAPK3	S137	R143Q	143	Missense	distal	6	no	10.411	10.342	EPSD	GDSC;CCLE	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P38936	CDKN1A	P27361	MAPK3	T145	R143Q	143	Missense	proximal	-2	no	9.904	9.541	EPSD	GDSC;CCLE	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q92934	BAD	P27361	MAPK3	S25	D29N	29	Missense	distal	4	no	18.920	18.893	EPSD	GDSC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q92934	BAD	P27361	MAPK3	S124	L129F	129	Missense	distal	5	no	10.499	10.345	EPSD	GDSC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q92934	BAD	P27361	MAPK3	T139	T137K	137	Missense	proximal	-2	no	9.743	8.388	EPSD	GDSC	9.358	Loss
CMGC_MAPK_ERK1_MAPK3_ST	Q92934	BAD	P27361	MAPK3	S144	F151L	151	Missense	distal	7	no	9.462	9.241	EPSD	GDSC;CCLE	9.358	Loss
CMGC_MAPK_ERK1_MAPK3_ST	Q92934	BAD	P27361	MAPK3	S144	T137K	137	Missense	distal	-7	no	9.462	9.469	EPSD	GDSC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q92934	BAD	P27361	MAPK3	S146	F151L	151	Missense	distal	5	no	12.087	12.240	EPSD	GDSC;CCLE	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q92934	BAD	P27361	MAPK3	S153	F151L	151	Missense	proximal	-2	no	9.155	10.147	EPSD	GDSC;CCLE	9.358	Gain
CMGC_MAPK_ERK1_MAPK3_ST	Q9H8Y8	GORASP2	P27361	MAPK3	S245	G248E	248	Missense	distal	3	no	16.426	16.428	EPSD	GDSC;CCLE	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q9H8Y8	GORASP2	P27361	MAPK3	S432	P434A	434	Missense	proximal	2	no	11.605	11.568	EPSD	GDSC;CCLE	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q9H8Y8	GORASP2	P27361	MAPK3	T433	P434A	434	Missense	proximal	1	no	18.295	9.056	EPSD	GDSC;CCLE	9.358	Loss
CMGC_MAPK_ERK1_MAPK3_ST	Q9H8Y8	GORASP2	P27361	MAPK3	S436	P434A	434	Missense	proximal	-2	no	11.768	9.417	EPSD	GDSC;CCLE	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q9H8Y8	GORASP2	P27361	MAPK3	S441	P434A	434	Missense	distal	-7	no	10.611	10.723	EPSD	GDSC;CCLE	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P19793	RXRA	P27361	MAPK3	S17	P22L	22	Missense	distal	5	no	9.954	9.727	EPSD	GDSC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P19793	RXRA	P27361	MAPK3	S18	R25*	25	Missense	distal	7	no	9.114	9.665	EPSD	GDSC	9.358	Gain
CMGC_MAPK_ERK1_MAPK3_ST	P19793	RXRA	P27361	MAPK3	S21	R25*	25	Missense	distal	4	no	18.489	18.069	EPSD	GDSC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P19793	RXRA	P27361	MAPK3	S21	P22L	22	Missense	proximal	1	no	18.489	9.451	EPSD	GDSC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P78536	ADAM17	P27361	MAPK3	S770	H771R	771	Missense	proximal	1	no	11.205	9.461	EPSD	GDSC;CCLE	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P78536	ADAM17	P27361	MAPK3	S770	Q763H	763	Missense	distal	-7	no	11.205	11.195	EPSD	GDSC;CCLE	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q8WX93	PALLD	P27361	MAPK3	S71	S71Y	71	Missense	central	0	yes	15.044	0.000	EPSD	GDSC;CCLE	9.358	Loss
CMGC_MAPK_ERK1_MAPK3_ST	Q8WX93	PALLD	P27361	MAPK3	T100	T100K	100	Missense	central	0	yes	14.893	0.000	EPSD	GDSC;CCLE	9.358	Loss
CMGC_MAPK_ERK1_MAPK3_ST	Q8WX93	PALLD	P27361	MAPK3	S115	S118*	118	Missense	distal	3	no	16.440	16.340	EPSD	GDSC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q8WX93	PALLD	P27361	MAPK3	S125	S118*	118	Missense	distal	-7	no	14.755	15.060	EPSD	GDSC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q8WX93	PALLD	P27361	MAPK3	T147	E141K	141	Missense	distal	-6	no	13.536	13.394	EPSD	GDSC;CCLE	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q8WX93	PALLD	P27361	MAPK3	S166	L168Q	168	Missense	proximal	2	no	9.452	9.453	EPSD	GDSC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q8WX93	PALLD	P27361	MAPK3	S166	P164H	164	Missense	proximal	-2	no	9.452	8.224	EPSD	GDSC;CCLE	9.358	Loss
CMGC_MAPK_ERK1_MAPK3_ST	Q8WX93	PALLD	P27361	MAPK3	S192	P193L	193	Missense	proximal	1	no	13.583	4.545	EPSD	GDSC;CCLE	9.358	Loss
CMGC_MAPK_ERK1_MAPK3_ST	Q8WX93	PALLD	P27361	MAPK3	S192	S199P	199	Missense	distal	7	no	13.583	13.660	EPSD	GDSC;CCLE	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q8WX93	PALLD	P27361	MAPK3	S198	S199P	199	Missense	proximal	1	no	7.428	16.481	EPSD	GDSC;CCLE	9.358	Gain
CMGC_MAPK_ERK1_MAPK3_ST	Q8WX93	PALLD	P27361	MAPK3	S199	P193L	193	Missense	distal	-6	no	15.780	15.532	EPSD	GDSC;CCLE	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q8WX93	PALLD	P27361	MAPK3	S199	S199P	199	Missense	central	0	yes	15.780	0.000	EPSD	GDSC;CCLE	9.358	Loss
CMGC_MAPK_ERK1_MAPK3_ST	Q8WX93	PALLD	P27361	MAPK3	S206	S199P	199	Missense	distal	-7	no	15.447	15.485	EPSD	GDSC;CCLE	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q8WX93	PALLD	P27361	MAPK3	S484	D486Y	486	Missense	proximal	2	no	15.389	15.379	EPSD	GDSC;CCLE	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q9UBN7	HDAC6	P27361	MAPK3	S412	R418W	418	Missense	distal	6	no	14.743	13.920	EPSD	GDSC;CCLE	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q9UBN7	HDAC6	P27361	MAPK3	T527	R529H	529	Missense	proximal	2	no	14.189	14.186	EPSD	GDSC;CCLE	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q9UBN7	HDAC6	P27361	MAPK3	T1031	P1033S	1033	Missense	proximal	2	no	16.435	16.437	EPSD;PhosphoSitePlus	GDSC;CCLE	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q9UBN7	HDAC6	P27361	MAPK3	S1035	P1033S	1033	Missense	proximal	-2	no	17.446	16.370	PhosphoSitePlus;EPSD	GDSC;CCLE	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q04637	EIF4G1	P27361	MAPK3	T43	Q37*	37	Missense	distal	-6	no	12.683	12.174	EPSD	GDSC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q04637	EIF4G1	P27361	MAPK3	S257	P264L	264	Missense	distal	7	no	10.015	10.208	EPSD	GDSC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q04637	EIF4G1	P27361	MAPK3	S261	P264L	264	Missense	distal	3	no	18.445	18.408	EPSD	GDSC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q04637	EIF4G1	P27361	MAPK3	S263	P264L	264	Missense	proximal	1	no	16.762	7.724	EPSD	GDSC	9.358	Loss
CMGC_MAPK_ERK1_MAPK3_ST	Q04637	EIF4G1	P27361	MAPK3	T265	P264L	264	Missense	proximal	-1	no	17.256	17.162	EPSD	GDSC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q04637	EIF4G1	P27361	MAPK3	S267	P264L	264	Missense	distal	-3	no	17.935	17.851	EPSD	GDSC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q04637	EIF4G1	P27361	MAPK3	S269	S276C	276	Missense	distal	7	no	18.952	19.564	EPSD	GDSC;CCLE	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q04637	EIF4G1	P27361	MAPK3	S269	P264L	264	Missense	distal	-5	no	18.952	18.898	EPSD	GDSC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q04637	EIF4G1	P27361	MAPK3	S314	A321V	321	Missense	distal	7	no	16.880	16.852	EPSD	GDSC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q04637	EIF4G1	P27361	MAPK3	S314	R312C	312	Missense	proximal	-2	no	16.880	14.764	EPSD	GDSC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q04637	EIF4G1	P27361	MAPK3	T318	A321V	321	Missense	distal	3	no	15.004	15.011	EPSD	GDSC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q04637	EIF4G1	P27361	MAPK3	T318	R312C	312	Missense	distal	-6	no	15.004	14.606	EPSD	GDSC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q04637	EIF4G1	P27361	MAPK3	S353	E360K	360	Missense	distal	7	no	9.377	9.448	EPSD	GDSC;CCLE	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q04637	EIF4G1	P27361	MAPK3	S488	P486S	486	Missense	proximal	-2	no	9.928	8.852	EPSD	GDSC	9.358	Loss
CMGC_MAPK_ERK1_MAPK3_ST	Q04637	EIF4G1	P27361	MAPK3	T489	P486S	486	Missense	distal	-3	no	14.445	14.437	EPSD	GDSC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q04637	EIF4G1	P27361	MAPK3	S598	E591*	591	Missense	distal	-7	no	9.166	9.438	EPSD	GDSC	9.358	Gain
CMGC_MAPK_ERK1_MAPK3_ST	Q04637	EIF4G1	P27361	MAPK3	T1179	D1175V	1175	Missense	distal	-4	no	14.976	14.860	EPSD	GDSC;CCLE	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q04637	EIF4G1	P27361	MAPK3	S1271	L1275H	1275	Missense	distal	4	no	14.412	14.475	EPSD	GDSC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P50616	TOB1	P27361	MAPK3	S152	H159Y	159	Missense	distal	7	no	16.831	16.949	EPSD;PhosphoSitePlus	GDSC;CCLE	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P50616	TOB1	P27361	MAPK3	S154	H159Y	159	Missense	distal	5	no	17.394	17.286	PhosphoSitePlus;EPSD	GDSC;CCLE	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P50616	TOB1	P27361	MAPK3	S164	H159Y	159	Missense	distal	-5	no	16.627	16.600	EPSD;PhosphoSitePlus	GDSC;CCLE	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P50616	TOB1	P27361	MAPK3	T166	H159Y	159	Missense	distal	-7	no	9.578	9.625	EPSD	GDSC;CCLE	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P49815	TSC2	P27361	MAPK3	S960	V963M	963	Missense	distal	3	no	14.575	14.550	EPSD	GDSC;CCLE	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P49815	TSC2	P27361	MAPK3	S1045	P1042R	1042	Missense	distal	-3	no	14.972	14.926	EPSD	GDSC;CCLE	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P49815	TSC2	P27361	MAPK3	S1155	R1159W	1159	Missense	distal	4	no	14.750	14.282	EPSD	GDSC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P49815	TSC2	P27361	MAPK3	S1411	S1411R	1411	Missense	central	0	yes	15.709	0.000	EPSD	GDSC;CCLE	9.358	Loss
CMGC_MAPK_ERK1_MAPK3_ST	P10415	BCL2	P27361	MAPK3	T56	P59T	59	Missense	distal	3	no	15.980	15.962	EPSD;PhosphoSitePlus	GDSC;CCLE	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P10415	BCL2	P27361	MAPK3	T56	H55P	55	Missense	proximal	-1	no	15.980	16.025	EPSD;PhosphoSitePlus	GDSC;CCLE	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q9NQ66	PLCB1	P27361	MAPK3	T39	I41F	41	Missense	proximal	2	no	15.226	15.211	EPSD	GDSC;CCLE	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q9NQ66	PLCB1	P27361	MAPK3	S387	V391L	391	Missense	distal	4	no	9.702	9.722	EPSD	GDSC;CCLE	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q9NQ66	PLCB1	P27361	MAPK3	S417	D416G	416	Missense	proximal	-1	no	16.108	16.089	EPSD	GDSC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q9NQ66	PLCB1	P27361	MAPK3	S417	E412Q	412	Missense	distal	-5	no	16.108	16.089	EPSD	GDSC;CCLE	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q9NQ66	PLCB1	P27361	MAPK3	S501	P502T	502	Missense	proximal	1	no	17.376	8.499	EPSD	GDSC	9.358	Loss
CMGC_MAPK_ERK1_MAPK3_ST	Q9NQ66	PLCB1	P27361	MAPK3	S501	P502L	502	Missense	proximal	1	no	17.376	8.338	EPSD	GDSC	9.358	Loss
CMGC_MAPK_ERK1_MAPK3_ST	Q9NQ66	PLCB1	P27361	MAPK3	S982	K975N	975	Missense	distal	-7	no	17.827	17.811	PhosphoSitePlus	GDSC;CCLE	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P17655	CAPN2	P27361	MAPK3	S50	A57S	57	Missense	distal	7	no	11.625	11.279	PhosphoSitePlus	GDSC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P17655	CAPN2	P27361	MAPK3	T406	T406I	406	Missense	central	0	yes	9.557	0.000	EPSD	GDSC	9.358	Loss
CMGC_MAPK_ERK1_MAPK3_ST	P28324	ELK4	P27361	MAPK3	S180	P181A	181	Missense	proximal	1	no	17.767	8.528	EPSD	GDSC;CCLE	9.358	Loss
CMGC_MAPK_ERK1_MAPK3_ST	P28324	ELK4	P27361	MAPK3	T185	P181A	181	Missense	distal	-4	no	14.448	14.343	EPSD	GDSC;CCLE	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P28324	ELK4	P27361	MAPK3	S215	I210V	210	Missense	distal	-5	no	16.641	16.659	EPSD	GDSC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	O75030	MITF	P27361	MAPK3	T23	E26K	26	Missense	distal	3	no	11.407	11.396	EPSD	GDSC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	O75030	MITF	P27361	MAPK3	S175	P178R	178	Missense	distal	3	no	10.252	10.225	EPSD	GDSC;CCLE	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	O75030	MITF	P27361	MAPK3	S180	P178R	178	Missense	proximal	-2	no	20.188	18.787	EPSD	GDSC;CCLE	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P03372	ESR1	P27361	MAPK3	S294	K299N	299	Missense	distal	5	no	14.592	14.621	EPSD	GDSC;CCLE	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P03372	ESR1	P27361	MAPK3	S294	I298V	298	Missense	distal	4	no	14.592	14.709	EPSD	GDSC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q13614	MTMR2	P27361	MAPK3	S26	S29C	29	Missense	distal	3	no	10.236	10.150	EPSD	GDSC;CCLE	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q13614	MTMR2	P27361	MAPK3	S27	S29C	29	Missense	proximal	2	no	10.494	10.432	EPSD	GDSC;CCLE	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q13614	MTMR2	P27361	MAPK3	S29	S29C	29	Missense	central	0	yes	10.079	0.000	EPSD	GDSC;CCLE	9.358	Loss
CMGC_MAPK_ERK1_MAPK3_ST	P41212	ETV6	P27361	MAPK3	S22	S26T	26	Missense	distal	4	no	18.707	18.594	EPSD	GDSC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P41212	ETV6	P27361	MAPK3	S29	S26T	26	Missense	distal	-3	no	9.503	9.473	EPSD	GDSC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P41212	ETV6	P27361	MAPK3	T31	S26T	26	Missense	distal	-5	no	15.403	15.387	EPSD	GDSC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P41212	ETV6	P27361	MAPK3	T161	R163M	163	Missense	proximal	2	no	13.998	13.967	EPSD	GDSC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P41212	ETV6	P27361	MAPK3	T161	S165Y	165	Missense	distal	4	no	13.998	13.782	EPSD	GDSC;CCLE	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P41212	ETV6	P27361	MAPK3	S213	P214S	214	Missense	proximal	1	no	15.938	6.885	EPSD;PhosphoSitePlus	GDSC;CCLE	9.358	Loss
CMGC_MAPK_ERK1_MAPK3_ST	P41212	ETV6	P27361	MAPK3	S236	N243D	243	Missense	distal	7	no	10.493	10.434	EPSD	GDSC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P41212	ETV6	P27361	MAPK3	S238	N243D	243	Missense	distal	5	no	17.742	17.822	EPSD	GDSC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P41212	ETV6	P27361	MAPK3	S248	N243D	243	Missense	distal	-5	no	9.596	9.602	EPSD	GDSC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P41212	ETV6	P27361	MAPK3	S257	Q260*	260	Missense	distal	3	no	18.675	18.597	PhosphoSitePlus;EPSD	GDSC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P41212	ETV6	P27361	MAPK3	S257	R259L	259	Missense	proximal	2	no	18.675	18.664	PhosphoSitePlus;EPSD	GDSC;CCLE	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P41212	ETV6	P27361	MAPK3	S257	S256F	256	Missense	proximal	-1	no	18.675	18.471	PhosphoSitePlus;EPSD	GDSC;CCLE	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P41212	ETV6	P27361	MAPK3	S307	Y314C	314	Missense	distal	7	no	9.603	9.960	EPSD	GDSC;CCLE	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P12980	LYL1	P27361	MAPK3	S260	R266G	266	Missense	distal	6	no	19.473	19.483	EPSD	GDSC;CCLE	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P12980	LYL1	P27361	MAPK3	S276	T273P	273	Missense	distal	-3	no	18.036	18.074	EPSD	GDSC;CCLE	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P12980	LYL1	P27361	MAPK3	S276	T273N	273	Missense	distal	-3	no	18.036	18.021	EPSD	GDSC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P08047	SP1	P27361	MAPK3	S59	A66G	66	Missense	distal	7	no	16.761	16.555	PhosphoSitePlus;EPSD	GDSC;CCLE	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P08047	SP1	P27361	MAPK3	S73	A66G	66	Missense	distal	-7	no	14.920	14.808	EPSD	GDSC;CCLE	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P08047	SP1	P27361	MAPK3	T739	T737A	737	Missense	proximal	-2	no	15.700	14.335	EPSD;PhosphoSitePlus	GDSC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P08047	SP1	P27361	MAPK3	T739	G736V	736	Missense	distal	-3	no	15.700	15.660	EPSD;PhosphoSitePlus	GDSC;CCLE	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P08047	SP1	P27361	MAPK3	T739	A738T	738	Missense	proximal	-1	no	15.700	15.803	EPSD;PhosphoSitePlus	GDSC;CCLE	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P55211	CASP9	P27361	MAPK3	T125	P123L	123	Missense	proximal	-2	no	16.610	15.226	PhosphoSitePlus	GDSC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P55211	CASP9	P27361	MAPK3	S302	E306K	306	Missense	distal	4	no	16.569	16.530	EPSD	GDSC;CCLE	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P55211	CASP9	P27361	MAPK3	S307	E306K	306	Missense	proximal	-1	no	16.881	16.851	EPSD	GDSC;CCLE	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	O43561	LAT	P27361	MAPK3	S35	D42N	42	Missense	distal	7	no	10.171	10.230	EPSD	GDSC;CCLE	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	O43561	LAT	P27361	MAPK3	S74	T68P	68	Missense	distal	-6	no	9.977	10.061	EPSD	GDSC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q15788	NCOA1	P27361	MAPK3	S16	S9F	9	Missense	distal	-7	no	12.112	12.332	EPSD	GDSC;CCLE	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q15788	NCOA1	P27361	MAPK3	S22	T26P	26	Missense	distal	4	no	17.253	17.317	EPSD	GDSC;CCLE	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q15788	NCOA1	P27361	MAPK3	S488	S482C	482	Missense	distal	-6	no	15.305	14.746	EPSD	GDSC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q15788	NCOA1	P27361	MAPK3	S488	I481T	481	Missense	distal	-7	no	15.305	15.190	EPSD	GDSC;CCLE	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q15788	NCOA1	P27361	MAPK3	T1026	T1020K	1020	Missense	distal	-6	no	13.828	13.838	EPSD	GDSC;CCLE	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q15788	NCOA1	P27361	MAPK3	T1179	P1180L	1180	Missense	proximal	1	no	17.543	8.505	PhosphoSitePlus;EPSD	GDSC;CCLE	9.358	Loss
CMGC_MAPK_ERK1_MAPK3_ST	Q15788	NCOA1	P27361	MAPK3	S1185	P1180L	1180	Missense	distal	-5	no	16.519	16.464	EPSD;PhosphoSitePlus	GDSC;CCLE	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q15788	NCOA1	P27361	MAPK3	T1426	G1423E	1423	Missense	distal	-3	no	20.148	20.161	EPSD	GDSC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q15788	NCOA1	P27361	MAPK3	T1426	S1422L	1422	Missense	distal	-4	no	20.148	20.008	EPSD	GDSC;CCLE	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q96RK0	CIC	P27361	MAPK3	S191	N193D	193	Missense	proximal	2	no	15.426	15.432	EPSD	GDSC;CCLE	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q96RK0	CIC	P27361	MAPK3	S502	P509A	509	Missense	distal	7	no	10.102	10.371	EPSD	GDSC;CCLE	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q96RK0	CIC	P27361	MAPK3	T583	A587V	587	Missense	distal	4	no	16.618	16.726	EPSD	GDSC;CCLE	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q96RK0	CIC	P27361	MAPK3	S700	N702S	702	Missense	proximal	2	no	15.564	15.582	EPSD	GDSC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q96RK0	CIC	P27361	MAPK3	S946	P952S	952	Missense	distal	6	no	16.358	16.488	EPSD	GDSC;CCLE	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q96RK0	CIC	P27361	MAPK3	T1318	R1321C	1321	Missense	distal	3	no	14.369	14.306	EPSD	GDSC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q96RK0	CIC	P27361	MAPK3	T1318	E1323V	1323	Missense	distal	5	no	14.369	14.126	EPSD	GDSC;CCLE	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q96RK0	CIC	P27361	MAPK3	S1373	S1378C	1378	Missense	distal	5	no	15.892	15.369	EPSD	GDSC;CCLE	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q96RK0	CIC	P27361	MAPK3	S1382	S1378C	1378	Missense	distal	-4	no	14.315	14.077	EPSD	GDSC;CCLE	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q96RK0	CIC	P27361	MAPK3	S1461	L1467V	1467	Missense	distal	6	no	9.672	9.590	EPSD	GDSC;CCLE	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P61586	RHOA	P27361	MAPK3	S73	Y66D	66	Missense	distal	-7	no	11.807	11.731	EPSD	GDSC;CCLE	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P61586	RHOA	P27361	MAPK3	T100	T100A	100	Missense	central	0	yes	13.651	0.000	EPSD;PhosphoSitePlus	GDSC;CCLE	9.358	Loss
CMGC_MAPK_ERK1_MAPK3_ST	Q92793	CREBBP	P27361	MAPK3	S93	G98V	98	Missense	distal	5	no	16.984	16.782	PhosphoSitePlus	GDSC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q92793	CREBBP	P27361	MAPK3	S448	Q443*	443	Missense	distal	-5	no	16.314	16.178	EPSD	GDSC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q92793	CREBBP	P27361	MAPK3	S448	P449L	449	Missense	proximal	1	no	16.314	7.276	EPSD	GDSC;CCLE	9.358	Loss
CMGC_MAPK_ERK1_MAPK3_ST	Q92793	CREBBP	P27361	MAPK3	S745	G740E	740	Missense	distal	-5	no	14.467	14.476	EPSD	GDSC;CCLE	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q92793	CREBBP	P27361	MAPK3	S1578	T1574A	1574	Missense	distal	-4	no	9.970	9.897	EPSD	GDSC;CCLE	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q92793	CREBBP	P27361	MAPK3	S1578	E1573A	1573	Missense	distal	-5	no	9.970	9.906	EPSD	GDSC;CCLE	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q92793	CREBBP	P27361	MAPK3	S1763	S1761*	1761	Missense	proximal	-2	no	17.993	13.546	EPSD	GDSC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q92793	CREBBP	P27361	MAPK3	S1763	R1769P	1769	Missense	distal	6	no	17.993	18.105	EPSD	GDSC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q92793	CREBBP	P27361	MAPK3	S1884	Q1879*	1879	Missense	distal	-5	no	17.209	17.073	EPSD	GDSC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q01860	POU5F1	P27361	MAPK3	S355	M357T	357	Missense	proximal	2	no	18.958	18.990	EPSD	GDSC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P49841	GSK3B	P27361	MAPK3	T7	T8P	8	Missense	proximal	1	no	8.076	16.953	EPSD	GDSC	9.358	Gain
CMGC_MAPK_ERK1_MAPK3_ST	P49841	GSK3B	P27361	MAPK3	T324	R319*	319	Missense	distal	-5	no	14.724	14.580	EPSD	GDSC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q16584	MAP3K11	P27361	MAPK3	S524	S524L	524	Missense	central	0	yes	15.473	0.000	EPSD	GDSC	9.358	Loss
CMGC_MAPK_ERK1_MAPK3_ST	Q16584	MAP3K11	P27361	MAPK3	S570	S569T	569	Missense	proximal	-1	no	17.779	17.748	EPSD	GDSC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q16584	MAP3K11	P27361	MAPK3	S674	T676R	676	Missense	proximal	2	no	16.454	16.453	EPSD	GDSC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q16584	MAP3K11	P27361	MAPK3	S674	P681S	681	Missense	distal	7	no	16.454	16.377	EPSD	GDSC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q16584	MAP3K11	P27361	MAPK3	T677	T676R	676	Missense	proximal	-1	no	17.924	17.913	EPSD	GDSC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q16584	MAP3K11	P27361	MAPK3	T677	P681S	681	Missense	distal	4	no	17.924	17.973	EPSD	GDSC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q16584	MAP3K11	P27361	MAPK3	T680	T676R	676	Missense	distal	-4	no	15.975	15.956	EPSD	GDSC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q16584	MAP3K11	P27361	MAPK3	T680	P681S	681	Missense	proximal	1	no	15.975	6.922	EPSD	GDSC	9.358	Loss
CMGC_MAPK_ERK1_MAPK3_ST	Q16584	MAP3K11	P27361	MAPK3	T682	T676R	676	Missense	distal	-6	no	15.983	15.991	EPSD	GDSC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q16584	MAP3K11	P27361	MAPK3	T682	P681S	681	Missense	proximal	-1	no	15.983	15.977	EPSD	GDSC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q16584	MAP3K11	P27361	MAPK3	S693	P692S	692	Missense	proximal	-1	no	17.772	17.766	EPSD	GDSC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q16584	MAP3K11	P27361	MAPK3	S780	R787W	787	Missense	distal	7	no	11.080	11.656	EPSD	GDSC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q16584	MAP3K11	P27361	MAPK3	S789	R787W	787	Missense	proximal	-2	no	16.353	14.456	EPSD	GDSC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q16584	MAP3K11	P27361	MAPK3	S793	R787W	787	Missense	distal	-6	no	17.525	17.002	EPSD	GDSC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q16584	MAP3K11	P27361	MAPK3	S815	A818P	818	Missense	distal	3	no	11.816	11.864	EPSD	GDSC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q96FF9	CDCA5	P27361	MAPK3	S15	G16E	16	Missense	proximal	1	no	8.350	10.641	EPSD	GDSC	9.358	Gain
CMGC_MAPK_ERK1_MAPK3_ST	Q96FF9	CDCA5	P27361	MAPK3	S21	G16E	16	Missense	distal	-5	no	17.568	17.577	EPSD	GDSC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q96FF9	CDCA5	P27361	MAPK3	T111	P109S	109	Missense	proximal	-2	no	16.827	15.751	EPSD	GDSC;CCLE	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q96FF9	CDCA5	P27361	MAPK3	S114	P109S	109	Missense	distal	-5	no	9.766	9.771	EPSD	GDSC;CCLE	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q96FF9	CDCA5	P27361	MAPK3	T115	P109S	109	Missense	distal	-6	no	15.340	15.425	EPSD	GDSC;CCLE	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q96FF9	CDCA5	P27361	MAPK3	S209	P210Q	210	Missense	proximal	1	no	14.429	6.485	PhosphoSitePlus;EPSD	GDSC	9.358	Loss
CMGC_MAPK_ERK1_MAPK3_ST	P23396	RPS3	P27361	MAPK3	T220	T221P	221	Missense	proximal	1	no	8.365	17.242	EPSD	GDSC	9.358	Gain
CMGC_MAPK_ERK1_MAPK3_ST	P23396	RPS3	P27361	MAPK3	T221	T221P	221	Missense	central	0	yes	19.601	0.000	EPSD	GDSC	9.358	Loss
CMGC_MAPK_ERK1_MAPK3_ST	P23396	RPS3	P27361	MAPK3	T221	D215V	215	Missense	distal	-6	no	19.601	19.332	EPSD	GDSC;CCLE	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P23396	RPS3	P27361	MAPK3	S224	T221P	221	Missense	distal	-3	no	11.691	11.730	EPSD	GDSC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q8IZP0	ABI1	P27361	MAPK3	T196	R194Q	194	Missense	proximal	-2	no	14.732	14.368	EPSD	GDSC;CCLE	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q8IZP0	ABI1	P27361	MAPK3	T336	G331A	331	Missense	distal	-5	no	15.296	15.240	EPSD	GDSC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q8IZP0	ABI1	P27361	MAPK3	S466	M468I	468	Missense	proximal	2	no	9.532	9.541	EPSD	GDSC;CCLE	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P35658	NUP214	P27361	MAPK3	S433	T439P	439	Missense	distal	6	no	9.866	9.891	EPSD	GDSC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P35658	NUP214	P27361	MAPK3	T434	T439P	439	Missense	distal	5	no	14.751	14.844	EPSD	GDSC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P35658	NUP214	P27361	MAPK3	T437	T439P	439	Missense	proximal	2	no	16.689	16.698	EPSD	GDSC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P35658	NUP214	P27361	MAPK3	S440	T439P	439	Missense	proximal	-1	no	9.966	10.002	EPSD	GDSC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P35658	NUP214	P27361	MAPK3	S441	T439P	439	Missense	proximal	-2	no	8.902	9.887	EPSD	GDSC	9.358	Gain
CMGC_MAPK_ERK1_MAPK3_ST	P35658	NUP214	P27361	MAPK3	S625	G622E	622	Missense	distal	-3	no	9.540	9.553	EPSD	GDSC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P35658	NUP214	P27361	MAPK3	T628	G622E	622	Missense	distal	-6	no	14.879	14.925	EPSD	GDSC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P35658	NUP214	P27361	MAPK3	S666	A673V	673	Missense	distal	7	no	17.714	17.686	EPSD	GDSC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P35658	NUP214	P27361	MAPK3	T670	A673V	673	Missense	distal	3	no	13.880	13.887	EPSD	GDSC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P35658	NUP214	P27361	MAPK3	S678	A673V	673	Missense	distal	-5	no	16.323	16.346	EPSD	GDSC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P35658	NUP214	P27361	MAPK3	S1081	A1088V	1088	Missense	distal	7	no	14.585	14.557	EPSD	GDSC;CCLE	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P35658	NUP214	P27361	MAPK3	T1243	Q1240*	1240	Missense	distal	-3	no	15.805	15.631	EPSD	GDSC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P35658	NUP214	P27361	MAPK3	S1307	A1302V	1302	Missense	distal	-5	no	9.475	9.498	EPSD	GDSC;CCLE	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P35658	NUP214	P27361	MAPK3	S1809	G1807R	1807	Missense	proximal	-2	no	15.741	16.457	PhosphoSitePlus;EPSD	GDSC;CCLE	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P35658	NUP214	P27361	MAPK3	S1963	F1970L	1970	Missense	distal	7	no	17.142	16.921	EPSD	GDSC;CCLE	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P35658	NUP214	P27361	MAPK3	T1981	P1986L	1986	Missense	distal	5	no	10.100	9.872	EPSD	GDSC;CCLE	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P35658	NUP214	P27361	MAPK3	S1985	P1986L	1986	Missense	proximal	1	no	14.286	5.248	EPSD	GDSC;CCLE	9.358	Loss
CMGC_MAPK_ERK1_MAPK3_ST	P35658	NUP214	P27361	MAPK3	S2002	S2006L	2006	Missense	distal	4	no	16.922	16.719	EPSD	GDSC;CCLE	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q15672	TWIST1	P27361	MAPK3	S99	E104Q	104	Missense	distal	5	no	17.724	17.602	EPSD	GDSC;CCLE	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q15672	TWIST1	P27361	MAPK3	S102	E104Q	104	Missense	proximal	2	no	10.246	10.233	EPSD	GDSC;CCLE	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q15796	SMAD2	P27361	MAPK3	S458	S464*	464	Missense	distal	6	no	15.165	14.232	EPSD	GDSC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q15796	SMAD2	P27361	MAPK3	S464	S464*	464	Missense	central	0	yes	9.782	0.000	EPSD	GDSC	9.358	Loss
CMGC_MAPK_ERK1_MAPK3_ST	P16144	ITGB4	P27361	MAPK3	S19	A15V	15	Missense	distal	-4	no	10.849	10.829	EPSD	GDSC;CCLE	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P16144	ITGB4	P27361	MAPK3	S99	D93Y	93	Missense	distal	-6	no	9.797	9.604	EPSD	GDSC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P16144	ITGB4	P27361	MAPK3	S99	Q104E	104	Missense	distal	5	no	9.797	9.919	EPSD	GDSC;CCLE	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P16144	ITGB4	P27361	MAPK3	S102	Q104E	104	Missense	proximal	2	no	16.331	16.344	EPSD	GDSC;CCLE	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P16144	ITGB4	P27361	MAPK3	S397	E404*	404	Missense	distal	7	no	9.948	10.564	EPSD	GDSC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P16144	ITGB4	P27361	MAPK3	S397	T393A	393	Missense	distal	-4	no	9.948	9.874	EPSD	GDSC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P16144	ITGB4	P27361	MAPK3	T776	S781G	781	Missense	distal	5	no	16.164	16.099	EPSD	GDSC;CCLE	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P16144	ITGB4	P27361	MAPK3	T776	G782E	782	Missense	distal	6	no	16.164	16.265	EPSD	GDSC;CCLE	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P16144	ITGB4	P27361	MAPK3	S1696	V1692L	1692	Missense	distal	-4	no	14.845	14.857	EPSD	GDSC;CCLE	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	O95817	BAG3	P27361	MAPK3	S7	M9V	9	Missense	proximal	2	no	16.326	16.344	EPSD	GDSC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	O95817	BAG3	P27361	MAPK3	S7	M1I	1	Missense	distal	-6	no	16.326	16.349	EPSD	GDSC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	O95817	BAG3	P27361	MAPK3	T62	G68A	68	Missense	distal	6	no	12.549	12.256	EPSD	GDSC;CCLE	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	O95817	BAG3	P27361	MAPK3	S64	G68A	68	Missense	distal	4	no	10.615	10.445	EPSD	GDSC;CCLE	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	O95817	BAG3	P27361	MAPK3	S65	G68A	68	Missense	distal	3	no	11.121	11.092	EPSD	GDSC;CCLE	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	O95817	BAG3	P27361	MAPK3	S173	G167R	167	Missense	distal	-6	no	15.221	15.123	EPSD	GDSC;CCLE	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	O95817	BAG3	P27361	MAPK3	S183	S187N	187	Missense	distal	4	no	9.410	9.264	EPSD	GDSC;CCLE	9.358	Loss
CMGC_MAPK_ERK1_MAPK3_ST	O95817	BAG3	P27361	MAPK3	S264	F266S	266	Missense	proximal	2	no	13.797	13.847	EPSD	GDSC;CCLE	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	O95817	BAG3	P27361	MAPK3	S279	R276Q	276	Missense	distal	-3	no	16.045	16.037	EPSD	GDSC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	O95817	BAG3	P27361	MAPK3	S291	V298M	298	Missense	distal	7	no	17.901	18.033	EPSD	GDSC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	O95817	BAG3	P27361	MAPK3	S377	P380S	380	Missense	distal	3	no	15.872	15.867	EPSD	GDSC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	O95817	BAG3	P27361	MAPK3	S386	P380S	380	Missense	distal	-6	no	17.196	17.280	EPSD	GDSC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	O95817	BAG3	P27361	MAPK3	T406	G411R	411	Missense	distal	5	no	13.749	13.670	EPSD	GDSC;CCLE	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P20339	RAB5A	P27361	MAPK3	T202	R197T	197	Missense	distal	-5	no	11.081	11.111	EPSD	GDSC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q15648	MED1	P27361	MAPK3	T212	H205Y	205	Missense	distal	-7	no	15.272	15.318	EPSD	GDSC;CCLE	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q15648	MED1	P27361	MAPK3	T212	Y210C	210	Missense	proximal	-2	no	15.272	13.065	EPSD	GDSC;CCLE	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q15648	MED1	P27361	MAPK3	T562	G559S	559	Missense	distal	-3	no	15.389	15.422	EPSD	GDSC;CCLE	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q15648	MED1	P27361	MAPK3	T562	F567L	567	Missense	distal	5	no	15.389	15.543	EPSD	GDSC;CCLE	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q15648	MED1	P27361	MAPK3	S675	G674S	674	Missense	proximal	-1	no	16.204	16.270	EPSD	GDSC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q15648	MED1	P27361	MAPK3	S675	M678I	678	Missense	distal	3	no	16.204	16.214	EPSD	GDSC;CCLE	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q15648	MED1	P27361	MAPK3	S675	I680M	680	Missense	distal	5	no	16.204	16.206	EPSD	GDSC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q15648	MED1	P27361	MAPK3	S848	A845T	845	Missense	distal	-3	no	15.619	15.680	EPSD	GDSC;CCLE	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q15648	MED1	P27361	MAPK3	S848	S851G	851	Missense	distal	3	no	15.619	15.603	EPSD	GDSC;CCLE	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q15648	MED1	P27361	MAPK3	S853	N856D	856	Missense	distal	3	no	17.767	17.777	EPSD	GDSC;CCLE	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q15648	MED1	P27361	MAPK3	S853	S851G	851	Missense	proximal	-2	no	17.767	16.726	EPSD	GDSC;CCLE	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q15648	MED1	P27361	MAPK3	S1207	G1201V	1201	Missense	distal	-6	no	14.894	14.627	EPSD	GDSC;CCLE	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q15648	MED1	P27361	MAPK3	S1223	I1225F	1225	Missense	proximal	2	no	15.688	15.673	EPSD	GDSC;CCLE	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q15648	MED1	P27361	MAPK3	S1374	S1375F	1375	Missense	proximal	1	no	6.933	9.772	EPSD	GDSC;CCLE	9.358	Gain
CMGC_MAPK_ERK1_MAPK3_ST	Q15648	MED1	P27361	MAPK3	S1401	S1403T	1403	Missense	proximal	2	no	16.180	16.169	EPSD	GDSC;CCLE	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q15648	MED1	P27361	MAPK3	S1536	D1541E	1541	Missense	distal	5	no	17.958	17.976	EPSD	GDSC;CCLE	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	O75582	RPS6KA5	P27361	MAPK3	S253	E260G	260	Missense	distal	7	no	14.937	14.972	EPSD	GDSC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	O75582	RPS6KA5	P27361	MAPK3	S253	D258H	258	Missense	distal	5	no	14.937	14.871	EPSD	GDSC;CCLE	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	O75582	RPS6KA5	P27361	MAPK3	T581	K580R	580	Missense	proximal	-1	no	17.145	17.159	EPSD;PhosphoSitePlus	GDSC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	O75582	RPS6KA5	P27361	MAPK3	S757	T755P	755	Missense	proximal	-2	no	8.622	9.607	EPSD	GDSC;CCLE	9.358	Gain
CMGC_MAPK_ERK1_MAPK3_ST	O75582	RPS6KA5	P27361	MAPK3	T793	S788R	788	Missense	distal	-5	no	9.895	9.849	EPSD	GDSC;CCLE	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P29590	PML	P27361	MAPK3	S527	P526T	526	Missense	proximal	-1	no	19.970	19.934	EPSD;PhosphoSitePlus	GDSC;CCLE	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P29590	PML	P27361	MAPK3	S527	V532I	532	Missense	distal	5	no	19.970	19.843	EPSD;PhosphoSitePlus	GDSC;CCLE	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P29590	PML	P27361	MAPK3	S530	P526T	526	Missense	distal	-4	no	18.937	18.906	EPSD;PhosphoSitePlus	GDSC;CCLE	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P29590	PML	P27361	MAPK3	S530	V532I	532	Missense	proximal	2	no	18.937	18.927	EPSD;PhosphoSitePlus	GDSC;CCLE	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P29590	PML	P27361	MAPK3	S804	M806V	806	Missense	proximal	2	no	10.169	10.187	EPSD	GDSC;CCLE	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P29590	PML	P27361	MAPK3	T867	R861Q	861	Missense	distal	-6	no	17.550	17.560	EPSD	GDSC;CCLE	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P29590	PML	P27361	MAPK3	T867	L869R	869	Missense	proximal	2	no	17.550	17.561	EPSD	GDSC;CCLE	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	O15027	SEC16A	P27361	MAPK3	T19	P13S	13	Missense	distal	-6	no	16.670	16.754	EPSD	GDSC;CCLE	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	O15027	SEC16A	P27361	MAPK3	S122	P128S	128	Missense	distal	6	no	11.074	11.204	EPSD	GDSC;CCLE	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	O15027	SEC16A	P27361	MAPK3	S122	S122G	122	Missense	central	0	yes	11.074	0.000	EPSD	GDSC	9.358	Loss
CMGC_MAPK_ERK1_MAPK3_ST	O15027	SEC16A	P27361	MAPK3	T123	P128S	128	Missense	distal	5	no	9.400	9.443	EPSD	GDSC;CCLE	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	O15027	SEC16A	P27361	MAPK3	T123	S122G	122	Missense	proximal	-1	no	9.400	9.334	EPSD	GDSC	9.358	Loss
CMGC_MAPK_ERK1_MAPK3_ST	O15027	SEC16A	P27361	MAPK3	S136	L139R	139	Missense	distal	3	no	13.354	13.364	EPSD	GDSC;CCLE	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	O15027	SEC16A	P27361	MAPK3	S153	H149P	149	Missense	distal	-4	no	9.913	9.948	EPSD	GDSC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	O15027	SEC16A	P27361	MAPK3	S164	G162E	162	Missense	proximal	-2	no	14.950	15.420	EPSD	GDSC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	O15027	SEC16A	P27361	MAPK3	S164	R168H	168	Missense	distal	4	no	14.950	14.956	EPSD	GDSC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	O15027	SEC16A	P27361	MAPK3	S164	R161Q	161	Missense	distal	-3	no	14.950	14.942	EPSD	GDSC;CCLE	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	O15027	SEC16A	P27361	MAPK3	S346	H339R	339	Missense	distal	-7	no	10.009	10.020	EPSD	GDSC;CCLE	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	O15027	SEC16A	P27361	MAPK3	S346	S342N	342	Missense	distal	-4	no	10.009	9.948	EPSD	GDSC;CCLE	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	O15027	SEC16A	P27361	MAPK3	S542	V538M	538	Missense	distal	-4	no	14.056	14.028	EPSD	GDSC;CCLE	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	O15027	SEC16A	P27361	MAPK3	S847	A846V	846	Missense	proximal	-1	no	9.555	9.604	EPSD	GDSC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	O15027	SEC16A	P27361	MAPK3	S1044	S1045P	1045	Missense	proximal	1	no	6.005	15.058	EPSD	GDSC	9.358	Gain
CMGC_MAPK_ERK1_MAPK3_ST	O15027	SEC16A	P27361	MAPK3	S1423	P1429R	1429	Missense	distal	6	no	9.762	9.650	EPSD	GDSC;CCLE	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	O15027	SEC16A	P27361	MAPK3	T1729	L1722P	1722	Missense	distal	-7	no	16.604	16.496	EPSD	GDSC;CCLE	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	O15027	SEC16A	P27361	MAPK3	S1905	P1900L	1900	Missense	distal	-5	no	18.669	18.614	EPSD	GDSC;CCLE	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	O15027	SEC16A	P27361	MAPK3	S1905	T1898R	1898	Missense	distal	-7	no	18.669	18.676	EPSD	GDSC;CCLE	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	O15027	SEC16A	P27361	MAPK3	S1905	T1898M	1898	Missense	distal	-7	no	18.669	18.798	EPSD	GDSC;CCLE	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	O15027	SEC16A	P27361	MAPK3	S1905	S1903F	1903	Missense	proximal	-2	no	18.669	17.369	EPSD	GDSC;CCLE	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	O15027	SEC16A	P27361	MAPK3	S1905	Q1899*	1899	Missense	distal	-6	no	18.669	18.161	EPSD	GDSC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	O15027	SEC16A	P27361	MAPK3	T2053	P2052L	2052	Missense	proximal	-1	no	13.944	13.850	EPSD	GDSC;CCLE	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q9NRA0	SPHK2	P27361	MAPK3	T503	S496F	496	Missense	distal	-7	no	14.766	14.985	EPSD	GDSC;CCLE	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P05412	JUN	P27361	MAPK3	T91	H87R	87	Missense	distal	-4	no	15.046	15.032	EPSD	GDSC;CCLE	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P05412	JUN	P27361	MAPK3	T93	H87R	87	Missense	distal	-6	no	12.688	12.692	EPSD	GDSC;CCLE	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q03060	CREM	P27361	MAPK3	S24	H26R	26	Missense	proximal	2	no	11.372	11.375	EPSD	GDSC;CCLE	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q00613	HSF1	P27361	MAPK3	S292	R296H	296	Missense	distal	4	no	16.604	16.611	EPSD	GDSC;CCLE	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q00613	HSF1	P27361	MAPK3	S303	P308L	308	Missense	distal	5	no	17.854	17.626	EPSD	GDSC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q00613	HSF1	P27361	MAPK3	S303	R296H	296	Missense	distal	-7	no	17.854	17.843	EPSD	GDSC;CCLE	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q00613	HSF1	P27361	MAPK3	S307	P308L	308	Missense	proximal	1	no	16.210	7.172	PhosphoSitePlus;EPSD	GDSC	9.358	Loss
CMGC_MAPK_ERK1_MAPK3_ST	Q00613	HSF1	P27361	MAPK3	S307	E312A	312	Missense	distal	5	no	16.210	15.979	PhosphoSitePlus;EPSD	GDSC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q00613	HSF1	P27361	MAPK3	S314	P308L	308	Missense	distal	-6	no	17.255	17.008	EPSD	GDSC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q00613	HSF1	P27361	MAPK3	S314	E312A	312	Missense	proximal	-2	no	17.255	16.550	EPSD	GDSC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q00613	HSF1	P27361	MAPK3	S363	R360Q	360	Missense	distal	-3	no	17.748	17.740	EPSD	GDSC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q00613	HSF1	P27361	MAPK3	S363	R360W	360	Missense	distal	-3	no	17.748	17.581	EPSD	GDSC;CCLE	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q00613	HSF1	P27361	MAPK3	S419	S419R	419	Missense	central	0	yes	15.478	0.000	EPSD	GDSC	9.358	Loss
CMGC_MAPK_ERK1_MAPK3_ST	Q00613	HSF1	P27361	MAPK3	S419	S421W	421	Missense	proximal	2	no	15.478	15.405	EPSD	GDSC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q00613	HSF1	P27361	MAPK3	S419	V422L	422	Missense	distal	3	no	15.478	15.483	EPSD	GDSC;CCLE	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q00613	HSF1	P27361	MAPK3	S458	S458I	458	Missense	central	0	yes	15.842	0.000	EPSD	GDSC;CCLE	9.358	Loss
CMGC_MAPK_ERK1_MAPK3_ST	Q00613	HSF1	P27361	MAPK3	S498	E502K	502	Missense	distal	4	no	9.746	9.708	EPSD	GDSC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q9UIG0	BAZ1B	P27361	MAPK3	S197	T203A	203	Missense	distal	6	no	17.898	17.527	EPSD	GDSC;CCLE	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q9UIG0	BAZ1B	P27361	MAPK3	S330	L332V	332	Missense	proximal	2	no	17.584	17.582	EPSD	GDSC;CCLE	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q9UIG0	BAZ1B	P27361	MAPK3	S423	K425R	425	Missense	proximal	2	no	16.421	16.424	EPSD	GDSC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q9UIG0	BAZ1B	P27361	MAPK3	S1468	S1468N	1468	Missense	central	0	yes	9.795	0.000	EPSD	GDSC	9.358	Loss
CMGC_MAPK_ERK1_MAPK3_ST	Q9ULV5	HSF4	P27361	MAPK3	S40	D34E	34	Missense	distal	-6	no	13.622	13.666	EPSD	GDSC;CCLE	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q9ULV5	HSF4	P27361	MAPK3	S298	D302G	302	Missense	distal	4	no	17.561	17.520	PhosphoSitePlus	GDSC;CCLE	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q9ULV5	HSF4	P27361	MAPK3	S340	G337W	337	Missense	distal	-3	no	14.072	13.899	EPSD	GDSC;CCLE	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q8N122	RPTOR	P27361	MAPK3	S696	L694F	694	Missense	proximal	-2	no	16.759	15.767	PhosphoSitePlus;EPSD	GDSC;CCLE	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q8N122	RPTOR	P27361	MAPK3	S711	R716I	716	Missense	distal	5	no	17.781	17.532	EPSD	GDSC;CCLE	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q8N122	RPTOR	P27361	MAPK3	S711	R718H	718	Missense	distal	7	no	17.781	17.749	EPSD	GDSC;CCLE	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q8N122	RPTOR	P27361	MAPK3	T714	R716I	716	Missense	proximal	2	no	15.978	15.955	EPSD	GDSC;CCLE	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q8N122	RPTOR	P27361	MAPK3	T714	R718H	718	Missense	distal	4	no	15.978	15.984	EPSD	GDSC;CCLE	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q8N122	RPTOR	P27361	MAPK3	S803	S798P	798	Missense	distal	-5	no	10.000	9.995	EPSD	GDSC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q8N122	RPTOR	P27361	MAPK3	S877	S881P	881	Missense	distal	4	no	16.346	16.297	EPSD	GDSC;CCLE	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q8N122	RPTOR	P27361	MAPK3	S881	S881P	881	Missense	central	0	yes	9.382	0.000	EPSD	GDSC;CCLE	9.358	Loss
CMGC_MAPK_ERK1_MAPK3_ST	Q8N122	RPTOR	P27361	MAPK3	T917	Y916H	916	Missense	proximal	-1	no	14.001	14.038	EPSD	GDSC;CCLE	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q8N122	RPTOR	P27361	MAPK3	S920	Y916H	916	Missense	distal	-4	no	10.601	10.642	EPSD	GDSC;CCLE	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P49407	ARRB1	P27361	MAPK3	T275	T275I	275	Missense	central	0	yes	14.733	0.000	EPSD	GDSC	9.358	Loss
CMGC_MAPK_ERK1_MAPK3_ST	P49407	ARRB1	P27361	MAPK3	T275	N280D	280	Missense	distal	5	no	14.733	14.813	EPSD	GDSC;CCLE	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P27361	MAPK3	P27361	MAPK3	S265	C271Y	271	Missense	distal	6	no	9.165	9.650	EPSD	GDSC;CCLE	9.358	Gain
CMGC_MAPK_ERK1_MAPK3_ST	P31645	SLC6A4	P27361	MAPK3	S52	N45S	45	Missense	distal	-7	no	17.221	17.154	EPSD	GDSC;CCLE	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P31645	SLC6A4	P27361	MAPK3	S52	S48L	48	Missense	distal	-4	no	17.221	17.081	EPSD	GDSC;CCLE	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P33076	CIITA	P27361	MAPK3	S288	P292S	292	Missense	distal	4	no	16.051	16.100	EPSD;PhosphoSitePlus	GDSC;CCLE	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P33076	CIITA	P27361	MAPK3	S288	P292A	292	Missense	distal	4	no	16.051	15.768	EPSD;PhosphoSitePlus	GDSC;CCLE	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P78347	GTF2I	P27361	MAPK3	T558	Q553E	553	Missense	distal	-5	no	15.496	15.515	EPSD	GDSC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	O43521	BCL2L11	P27361	MAPK3	S59	G62V	62	Missense	distal	3	no	16.761	16.739	EPSD	GDSC;CCLE	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	O43521	BCL2L11	P27361	MAPK3	S69	G62V	62	Missense	distal	-7	no	18.489	18.601	PhosphoSitePlus	GDSC;CCLE	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	O43521	BCL2L11	P27361	MAPK3	S98	G95E	95	Missense	distal	-3	no	10.615	10.628	EPSD	GDSC;CCLE	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	O43521	BCL2L11	P27361	MAPK3	S104	A106P	106	Missense	proximal	2	no	14.210	14.247	EPSD	GDSC;CCLE	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P42229	STAT5A	P27361	MAPK3	S726	Q732H	732	Missense	distal	6	no	15.734	15.822	EPSD	GDSC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P42229	STAT5A	P27361	MAPK3	S726	P731L	731	Missense	distal	5	no	15.734	15.506	EPSD	GDSC;CCLE	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P42229	STAT5A	P27361	MAPK3	S788	A789T	789	Missense	proximal	1	no	9.126	9.488	EPSD	GDSC;CCLE	9.358	Gain
CMGC_MAPK_ERK1_MAPK3_ST	Q15366	PCBP2	P27361	MAPK3	S208	A207V	207	Missense	proximal	-1	no	11.745	11.795	EPSD	GDSC;CCLE	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q15366	PCBP2	P27361	MAPK3	T213	A207V	207	Missense	distal	-6	no	14.340	14.327	EPSD;PhosphoSitePlus	GDSC;CCLE	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q8N9N5	BANP	P27361	MAPK3	S19	P23S	23	Missense	distal	4	no	19.122	19.171	EPSD	GDSC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q8N9N5	BANP	P27361	MAPK3	T337	F333V	333	Missense	distal	-4	no	16.081	16.118	PhosphoSitePlus;EPSD	GDSC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q16559	TAL2	P27361	MAPK3	S100	V98I	98	Missense	proximal	-2	no	19.528	19.343	PhosphoSitePlus	GDSC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	O00429	DNM1L	P27361	MAPK3	S136	P137T	137	Missense	proximal	1	no	16.887	8.010	EPSD	GDSC	9.358	Loss
CMGC_MAPK_ERK1_MAPK3_ST	O00429	DNM1L	P27361	MAPK3	S136	V139I	139	Missense	distal	3	no	16.887	16.873	EPSD	GDSC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	O00429	DNM1L	P27361	MAPK3	S544	A551T	551	Missense	distal	7	no	9.422	9.195	EPSD	GDSC;CCLE	9.358	Loss
CMGC_MAPK_ERK1_MAPK3_ST	O00429	DNM1L	P27361	MAPK3	S544	P547L	547	Missense	distal	3	no	9.422	9.385	EPSD	GDSC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	O00429	DNM1L	P27361	MAPK3	S544	A550D	550	Missense	distal	6	no	9.422	9.771	EPSD	GDSC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	O00429	DNM1L	P27361	MAPK3	S548	A551T	551	Missense	distal	3	no	16.860	16.891	EPSD	GDSC;CCLE	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	O00429	DNM1L	P27361	MAPK3	S548	P547L	547	Missense	proximal	-1	no	16.860	16.766	EPSD	GDSC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	O00429	DNM1L	P27361	MAPK3	S548	A550D	550	Missense	proximal	2	no	16.860	16.887	EPSD	GDSC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	O00429	DNM1L	P27361	MAPK3	S724	Q725E	725	Missense	proximal	1	no	10.850	9.546	EPSD	GDSC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P17542	TAL1	P27361	MAPK3	S300	T305M	305	Missense	distal	5	no	15.182	14.926	EPSD	GDSC;CCLE	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P17542	TAL1	P27361	MAPK3	S303	A309S	309	Missense	distal	6	no	11.936	12.462	EPSD	GDSC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P17542	TAL1	P27361	MAPK3	S303	T305M	305	Missense	proximal	2	no	11.936	11.904	EPSD	GDSC;CCLE	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P17542	TAL1	P27361	MAPK3	T313	A309S	309	Missense	distal	-4	no	9.647	9.779	EPSD	GDSC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P17542	TAL1	P27361	MAPK3	T313	T313A	313	Missense	central	0	yes	9.647	0.000	EPSD	GDSC;CCLE	9.358	Loss
CMGC_MAPK_ERK1_MAPK3_ST	P17542	TAL1	P27361	MAPK3	S316	A309S	309	Missense	distal	-7	no	9.898	9.748	EPSD	GDSC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P17542	TAL1	P27361	MAPK3	S316	T313A	313	Missense	distal	-3	no	9.898	9.837	EPSD	GDSC;CCLE	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q13485	SMAD4	P27361	MAPK3	S138	S144*	144	Missense	distal	6	no	15.185	14.251	EPSD	GDSC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q13485	SMAD4	P27361	MAPK3	S138	R135*	135	Missense	distal	-3	no	15.185	15.003	EPSD	GDSC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P00533	EGFR	P27361	MAPK3	S77	Q71*	71	Missense	distal	-6	no	10.908	10.400	EPSD	GDSC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P00533	EGFR	P27361	MAPK3	S77	S77F	77	Missense	central	0	yes	10.908	0.000	EPSD	GDSC	9.358	Loss
CMGC_MAPK_ERK1_MAPK3_ST	P00533	EGFR	P27361	MAPK3	S227	N234D	234	Missense	distal	7	no	15.963	15.904	EPSD	GDSC;CCLE	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P00533	EGFR	P27361	MAPK3	S229	N234D	234	Missense	distal	5	no	10.196	10.277	EPSD	GDSC;CCLE	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P00533	EGFR	P27361	MAPK3	S752	A750E	750	Missense	proximal	-2	no	15.913	16.617	EPSD	GDSC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P00533	EGFR	P27361	MAPK3	T1085	T1085N	1085	Missense	central	0	yes	10.911	0.000	EPSD	GDSC;CCLE	9.358	Loss
CMGC_MAPK_ERK1_MAPK3_ST	P00533	EGFR	P27361	MAPK3	S1153	W1157C	1157	Missense	distal	4	no	15.338	15.448	EPSD	GDSC;CCLE	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P63000	RAC1	P27361	MAPK3	S71	Y64H	64	Missense	distal	-7	no	11.073	11.026	EPSD	GDSC;CCLE	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	O60244	MED14	P27361	MAPK3	S1101	R1105*	1105	Missense	distal	4	no	14.180	13.760	EPSD	GDSC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	O60244	MED14	P27361	MAPK3	S1112	R1105*	1105	Missense	distal	-7	no	16.484	16.706	EPSD	GDSC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P29966	MARCKS	P27361	MAPK3	S314	P313L	313	Missense	proximal	-1	no	11.578	11.483	EPSD	GDSC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	O43524	FOXO3	P27361	MAPK3	S325	V320I	320	Missense	distal	-5	no	15.988	15.970	EPSD	GDSC;CCLE	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	O43524	FOXO3	P27361	MAPK3	S402	M408V	408	Missense	distal	6	no	15.143	15.354	EPSD	GDSC;CCLE	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	O43524	FOXO3	P27361	MAPK3	S413	R410W	410	Missense	distal	-3	no	9.925	9.757	EPSD	GDSC;CCLE	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	O43524	FOXO3	P27361	MAPK3	S413	M408V	408	Missense	distal	-5	no	9.925	9.967	EPSD	GDSC;CCLE	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	O43524	FOXO3	P27361	MAPK3	S574	V576A	576	Missense	proximal	2	no	15.818	15.805	EPSD	GDSC;CCLE	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q13115	DUSP4	P27361	MAPK3	S318	S315I	315	Missense	distal	-3	no	15.499	15.388	EPSD	GDSC;CCLE	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q13115	DUSP4	P27361	MAPK3	S318	R314C	314	Missense	distal	-4	no	15.499	15.338	EPSD	GDSC;CCLE	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q9UHB6	LIMA1	P27361	MAPK3	T337	A333T	333	Missense	distal	-4	no	14.391	14.465	EPSD	GDSC;CCLE	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P24941	CDK2	P27361	MAPK3	T221	D223G	223	Missense	proximal	2	no	17.340	17.334	EPSD	GDSC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q05209	PTPN12	P27361	MAPK3	S19	N23T	23	Missense	distal	4	no	15.619	15.652	EPSD	GDSC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q05209	PTPN12	P27361	MAPK3	T81	R74*	74	Missense	distal	-7	no	15.493	15.714	EPSD	GDSC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q05209	PTPN12	P27361	MAPK3	T81	T78P	78	Missense	distal	-3	no	15.493	15.531	EPSD	GDSC;CCLE	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q05209	PTPN12	P27361	MAPK3	S342	C343F	343	Missense	proximal	1	no	2.180	11.274	EPSD	GDSC;CCLE	9.358	Gain
CMGC_MAPK_ERK1_MAPK3_ST	Q05209	PTPN12	P27361	MAPK3	S468	S466Y	466	Missense	proximal	-2	no	17.703	17.470	EPSD	GDSC;CCLE	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q05209	PTPN12	P27361	MAPK3	T578	H584Y	584	Missense	distal	6	no	13.705	13.546	EPSD	GDSC;CCLE	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q05209	PTPN12	P27361	MAPK3	S588	H584Y	584	Missense	distal	-4	no	16.520	16.480	EPSD	GDSC;CCLE	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q05209	PTPN12	P27361	MAPK3	S684	E690K	690	Missense	distal	6	no	12.824	12.748	EPSD	GDSC;CCLE	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q05209	PTPN12	P27361	MAPK3	T693	E690K	690	Missense	distal	-3	no	14.867	14.835	EPSD	GDSC;CCLE	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q96Q27	ASB2	P27361	MAPK3	S28	A24S	24	Missense	distal	-4	no	10.955	11.087	EPSD	GDSC;CCLE	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q96Q27	ASB2	P27361	MAPK3	S29	A24S	24	Missense	distal	-5	no	17.534	17.633	EPSD	GDSC;CCLE	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P16949	STMN1	P27361	MAPK3	S38	P36T	36	Missense	proximal	-2	no	17.700	16.714	EPSD;PhosphoSitePlus	GDSC;CCLE	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q9UKX7	NUP50	P27361	MAPK3	S296	P297L	297	Missense	proximal	1	no	17.582	8.544	EPSD	GDSC;CCLE	9.358	Loss
CMGC_MAPK_ERK1_MAPK3_ST	Q15746	MYLK	P27361	MAPK3	S259	E263*	263	Missense	distal	4	no	9.463	8.997	EPSD	GDSC	9.358	Loss
CMGC_MAPK_ERK1_MAPK3_ST	Q15746	MYLK	P27361	MAPK3	T335	P336L	336	Missense	proximal	1	no	15.827	6.789	EPSD	GDSC	9.358	Loss
CMGC_MAPK_ERK1_MAPK3_ST	Q15746	MYLK	P27361	MAPK3	S515	A513V	513	Missense	proximal	-2	no	9.561	10.258	EPSD	GDSC;CCLE	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q15746	MYLK	P27361	MAPK3	S947	R954H	954	Missense	distal	7	no	16.192	16.160	EPSD	GDSC;CCLE	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q15746	MYLK	P27361	MAPK3	T978	P973L	973	Missense	distal	-5	no	18.294	18.239	EPSD	GDSC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q15746	MYLK	P27361	MAPK3	S1208	V1213L	1213	Missense	distal	5	no	9.454	9.450	EPSD	GDSC;CCLE	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q15746	MYLK	P27361	MAPK3	S1776	G1775E	1775	Missense	proximal	-1	no	16.022	16.063	EPSD	GDSC;CCLE	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q15746	MYLK	P27361	MAPK3	S1776	S1776P	1776	Missense	central	0	yes	16.022	0.000	EPSD	GDSC;CCLE	9.358	Loss
CMGC_MAPK_ERK1_MAPK3_ST	Q15746	MYLK	P27361	MAPK3	S1779	G1775E	1775	Missense	distal	-4	no	17.370	17.384	PhosphoSitePlus	GDSC;CCLE	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q15746	MYLK	P27361	MAPK3	S1779	L1786I	1786	Missense	distal	7	no	17.370	17.498	PhosphoSitePlus	GDSC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q15746	MYLK	P27361	MAPK3	S1779	S1776P	1776	Missense	distal	-3	no	17.370	17.378	PhosphoSitePlus	GDSC;CCLE	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	O75581	LRP6	P27361	MAPK3	S1490	R1495Q	1495	Missense	distal	5	no	18.153	18.151	PhosphoSitePlus;EPSD	GDSC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	O75581	LRP6	P27361	MAPK3	S1607	S1612F	1612	Missense	distal	5	no	21.647	21.223	EPSD	GDSC;CCLE	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	O75581	LRP6	P27361	MAPK3	S1612	S1612F	1612	Missense	central	0	yes	11.066	0.000	EPSD	GDSC;CCLE	9.358	Loss
CMGC_MAPK_ERK1_MAPK3_ST	Q02447	SP3	P27361	MAPK3	T115	D121E	121	Missense	distal	6	no	14.514	14.559	EPSD	GDSC;CCLE	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q02447	SP3	P27361	MAPK3	S375	S375L	375	Missense	central	0	yes	17.585	0.000	EPSD	GDSC;CCLE	9.358	Loss
CMGC_MAPK_ERK1_MAPK3_ST	Q02447	SP3	P27361	MAPK3	S375	L368F	368	Missense	distal	-7	no	17.585	17.660	EPSD	GDSC;CCLE	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q8IX03	WWC1	P27361	MAPK3	S358	E353Q	353	Missense	distal	-5	no	15.901	15.882	EPSD	GDSC;CCLE	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q8IX03	WWC1	P27361	MAPK3	S899	K906E	906	Missense	distal	7	no	16.387	16.316	EPSD	GDSC;CCLE	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q8IX03	WWC1	P27361	MAPK3	T912	K906E	906	Missense	distal	-6	no	14.243	14.384	EPSD	GDSC;CCLE	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q8IX03	WWC1	P27361	MAPK3	T912	L919F	919	Missense	distal	7	no	14.243	14.464	EPSD	GDSC;CCLE	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q8IX03	WWC1	P27361	MAPK3	S914	L919F	919	Missense	distal	5	no	9.490	9.336	EPSD	GDSC;CCLE	9.358	Loss
CMGC_MAPK_ERK1_MAPK3_ST	Q8IX03	WWC1	P27361	MAPK3	S914	R920Q	920	Missense	distal	6	no	9.490	9.420	EPSD	GDSC;CCLE	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q8IX03	WWC1	P27361	MAPK3	S936	R941Q	941	Missense	distal	5	no	9.850	9.848	EPSD	GDSC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P14784	IL2RB	P27361	MAPK3	S431	G437S	437	Missense	distal	6	no	14.421	14.654	EPSD	GDSC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P14784	IL2RB	P27361	MAPK3	T476	T476I	476	Missense	central	0	yes	15.038	0.000	PhosphoSitePlus	GDSC	9.358	Loss
CMGC_MAPK_ERK1_MAPK3_ST	P14784	IL2RB	P27361	MAPK3	T533	L531V	531	Missense	proximal	-2	no	9.774	9.504	EPSD	GDSC;CCLE	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P14784	IL2RB	P27361	MAPK3	S538	L531V	531	Missense	distal	-7	no	10.159	10.164	EPSD	GDSC;CCLE	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P06239	LCK	P27361	MAPK3	S162	V167I	167	Missense	distal	5	no	9.683	9.557	EPSD	GDSC;CCLE	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P06239	LCK	P27361	MAPK3	S194	G201S	201	Missense	distal	7	no	16.825	16.686	EPSD	GDSC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P06239	LCK	P27361	MAPK3	S373	S377R	377	Missense	distal	4	no	9.982	9.835	EPSD	GDSC;CCLE	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P42702	LIFR	P27361	MAPK3	T904	V910F	910	Missense	distal	6	no	15.727	15.451	EPSD	GDSC;CCLE	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P42702	LIFR	P27361	MAPK3	S927	E931K	931	Missense	distal	4	no	16.348	16.310	EPSD	GDSC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P42702	LIFR	P27361	MAPK3	S927	D922G	922	Missense	distal	-5	no	16.348	16.340	EPSD	GDSC;CCLE	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P42702	LIFR	P27361	MAPK3	S927	E921K	921	Missense	distal	-6	no	16.348	16.207	EPSD	GDSC;CCLE	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P42702	LIFR	P27361	MAPK3	S1041	N1035H	1035	Missense	distal	-6	no	17.599	17.557	EPSD	GDSC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P42702	LIFR	P27361	MAPK3	S1056	S1059G	1059	Missense	distal	3	no	11.583	11.568	EPSD	GDSC;CCLE	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P42702	LIFR	P27361	MAPK3	S1059	S1059G	1059	Missense	central	0	yes	16.075	0.000	EPSD	GDSC;CCLE	9.358	Loss
CMGC_MAPK_ERK1_MAPK3_ST	P42702	LIFR	P27361	MAPK3	S1062	S1059G	1059	Missense	distal	-3	no	11.245	11.212	EPSD	GDSC;CCLE	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q14247	CTTN	P27361	MAPK3	S405	Q409K	409	Missense	distal	4	no	18.528	18.580	PhosphoSitePlus;EPSD	GDSC;CCLE	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q08499	PDE4D	P27361	MAPK3	S18	R11S	11	Missense	distal	-7	no	10.692	10.609	EPSD	GDSC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q08499	PDE4D	P27361	MAPK3	S164	D167Y	167	Missense	distal	3	no	13.348	13.328	EPSD	GDSC;CCLE	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q08499	PDE4D	P27361	MAPK3	S171	D167Y	167	Missense	distal	-4	no	15.078	15.010	EPSD	GDSC;CCLE	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q08499	PDE4D	P27361	MAPK3	S202	D200E	200	Missense	proximal	-2	no	16.308	16.269	EPSD	GDSC;CCLE	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q08499	PDE4D	P27361	MAPK3	T224	V223A	223	Missense	proximal	-1	no	13.622	13.572	EPSD	GDSC;CCLE	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q08499	PDE4D	P27361	MAPK3	S255	Q260*	260	Missense	distal	5	no	15.109	14.648	EPSD	GDSC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q08499	PDE4D	P27361	MAPK3	S348	I346M	346	Missense	proximal	-2	no	16.099	15.184	EPSD	GDSC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q08499	PDE4D	P27361	MAPK3	S374	I381S	381	Missense	distal	7	no	9.804	9.406	EPSD	GDSC;CCLE	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q08499	PDE4D	P27361	MAPK3	S375	I381S	381	Missense	distal	6	no	9.111	9.680	EPSD	GDSC;CCLE	9.358	Gain
CMGC_MAPK_ERK1_MAPK3_ST	Q08499	PDE4D	P27361	MAPK3	S715	Q714L	714	Missense	proximal	-1	no	20.327	20.319	EPSD	GDSC;CCLE	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q08499	PDE4D	P27361	MAPK3	S717	Q714L	714	Missense	distal	-3	no	14.599	14.569	EPSD	GDSC;CCLE	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	O95644	NFATC1	P27361	MAPK3	S278	P275L	275	Missense	distal	-3	no	18.844	18.760	EPSD	GDSC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	O95644	NFATC1	P27361	MAPK3	S282	P275L	275	Missense	distal	-7	no	17.928	18.035	EPSD	GDSC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P04637	TP53	P27361	MAPK3	S33	Q38*	38	Missense	distal	5	no	15.325	14.865	EPSD	GDSC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P04637	TP53	P27361	MAPK3	T81	A74S	74	Missense	distal	-7	no	16.918	16.768	EPSD	GDSC;CCLE	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P04637	TP53	P27361	MAPK3	S127	Y126*	126	Missense	proximal	-1	no	16.318	16.122	EPSD	GDSC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P04637	TP53	P27361	MAPK3	S127	K120*	120	Missense	distal	-7	no	16.318	16.539	EPSD	GDSC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P04637	TP53	P27361	MAPK3	T150	Q144*	144	Missense	distal	-6	no	12.555	12.047	EPSD	GDSC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P04637	TP53	P27361	MAPK3	T150	W146*	146	Missense	distal	-4	no	12.555	12.541	EPSD	GDSC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P04637	TP53	P27361	MAPK3	S315	Q317*	317	Missense	proximal	2	no	16.542	16.486	EPSD	GDSC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P04637	TP53	P27361	MAPK3	S315	K319*	319	Missense	distal	4	no	16.542	16.114	EPSD	GDSC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P04637	TP53	P27361	MAPK3	S367	G360V	360	Missense	distal	-7	no	10.558	10.670	EPSD	GDSC;CCLE	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P04637	TP53	P27361	MAPK3	S392	G389W	389	Missense	distal	-3	no	10.933	10.760	PhosphoSitePlus;EPSD	GDSC;CCLE	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P27708	CAD	P27361	MAPK3	S1267	P1264H	1264	Missense	distal	-3	no	11.697	11.657	EPSD	GDSC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P27708	CAD	P27361	MAPK3	T1884	P1891H	1891	Missense	distal	7	no	13.281	13.341	EPSD	GDSC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P27708	CAD	P27361	MAPK3	T1884	Y1890C	1890	Missense	distal	6	no	13.281	12.796	EPSD	GDSC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P27708	CAD	P27361	MAPK3	S1900	V1895I	1895	Missense	distal	-5	no	15.232	15.213	EPSD	GDSC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q969H0	FBXW7	P27361	MAPK3	S688	E694*	694	Missense	distal	6	no	9.905	9.104	EPSD	GDSC	9.358	Loss
CMGC_MAPK_ERK1_MAPK3_ST	P10275	AR	P27361	MAPK3	S516	E523D	523	Missense	distal	7	no	17.503	17.505	EPSD;PhosphoSitePlus	GDSC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P35228	NOS2	P27361	MAPK3	S37	V39A	39	Missense	proximal	2	no	16.647	16.633	EPSD	GDSC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P35228	NOS2	P27361	MAPK3	T77	S81Y	81	Missense	distal	4	no	15.836	15.620	EPSD	GDSC;CCLE	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P35228	NOS2	P27361	MAPK3	S80	S81Y	81	Missense	proximal	1	no	9.549	11.554	EPSD	GDSC;CCLE	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P35228	NOS2	P27361	MAPK3	S81	S81Y	81	Missense	central	0	yes	15.418	0.000	EPSD	GDSC;CCLE	9.358	Loss
CMGC_MAPK_ERK1_MAPK3_ST	P13631	RARG	P27361	MAPK3	S43	G50D	50	Missense	distal	7	no	14.622	14.590	EPSD	GDSC;CCLE	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P33981	TTK	P27361	MAPK3	S281	P275T	275	Missense	distal	-6	no	17.437	17.353	EPSD	GDSC;CCLE	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P33981	TTK	P27361	MAPK3	S436	P438S	438	Missense	proximal	2	no	17.730	17.731	EPSD	GDSC;CCLE	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P33981	TTK	P27361	MAPK3	S440	P438S	438	Missense	proximal	-2	no	9.428	8.352	EPSD	GDSC;CCLE	9.358	Loss
CMGC_MAPK_ERK1_MAPK3_ST	Q86UR1	NOXA1	P27361	MAPK3	S470	A463T	463	Missense	distal	-7	no	14.527	14.454	EPSD	GDSC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q86UR1	NOXA1	P27361	MAPK3	S470	A463P	463	Missense	distal	-7	no	14.527	14.415	EPSD	GDSC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	O60331	PIP5K1C	P27361	MAPK3	S355	Q362*	362	Missense	distal	7	no	9.471	9.992	EPSD	GDSC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	O60331	PIP5K1C	P27361	MAPK3	S515	A519S	519	Missense	distal	4	no	11.215	11.546	EPSD	GDSC;CCLE	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	O60331	PIP5K1C	P27361	MAPK3	S539	T543M	543	Missense	distal	4	no	16.757	16.491	EPSD	GDSC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	O60331	PIP5K1C	P27361	MAPK3	T553	R550G	550	Missense	distal	-3	no	10.824	10.829	EPSD	GDSC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P27824	CANX	P27361	MAPK3	S55	S54L	54	Missense	proximal	-1	no	18.319	18.230	EPSD	GDSC;CCLE	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P27824	CANX	P27361	MAPK3	S564	G560D	560	Missense	distal	-4	no	11.048	11.052	EPSD	GDSC;CCLE	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q12931	TRAP1	P27361	MAPK3	S472	R469C	469	Missense	distal	-3	no	9.483	9.343	EPSD	GDSC	9.358	Loss
CMGC_MAPK_ERK1_MAPK3_ST	Q92908	GATA6	P27361	MAPK3	T34	F27L	27	Missense	distal	-7	no	17.386	17.311	EPSD	GDSC;CCLE	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q92908	GATA6	P27361	MAPK3	S37	S44F	44	Missense	distal	7	no	19.186	19.677	EPSD	GDSC;CCLE	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q92908	GATA6	P27361	MAPK3	S43	S44F	44	Missense	proximal	1	no	7.707	10.546	EPSD	GDSC;CCLE	9.358	Gain
CMGC_MAPK_ERK1_MAPK3_ST	Q92908	GATA6	P27361	MAPK3	S44	G50R	50	Missense	distal	6	no	9.510	9.501	EPSD	GDSC;CCLE	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q92908	GATA6	P27361	MAPK3	S44	S44F	44	Missense	central	0	yes	9.510	0.000	EPSD	GDSC;CCLE	9.358	Loss
CMGC_MAPK_ERK1_MAPK3_ST	Q92908	GATA6	P27361	MAPK3	S44	G49C	49	Missense	distal	5	no	9.510	9.051	EPSD	GDSC;CCLE	9.358	Loss
CMGC_MAPK_ERK1_MAPK3_ST	Q92908	GATA6	P27361	MAPK3	T62	E68V	68	Missense	distal	6	no	10.474	10.167	EPSD	GDSC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q92908	GATA6	P27361	MAPK3	S531	S531F	531	Missense	central	0	yes	17.038	0.000	EPSD	GDSC;CCLE	9.358	Loss
CMGC_MAPK_ERK1_MAPK3_ST	Q92908	GATA6	P27361	MAPK3	T534	S531F	531	Missense	distal	-3	no	9.798	9.656	EPSD	GDSC;CCLE	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q86UC2	RSPH3	P27361	MAPK3	S553	G555W	555	Missense	proximal	2	no	11.104	11.048	EPSD	GDSC;CCLE	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q9UQC2	GAB2	P27361	MAPK3	S218	T225I	225	Missense	distal	7	no	11.306	11.586	EPSD	GDSC;CCLE	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q9UQC2	GAB2	P27361	MAPK3	T265	S264G	264	Missense	proximal	-1	no	9.756	9.690	EPSD	GDSC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q9UQC2	GAB2	P27361	MAPK3	T294	T294I	294	Missense	central	0	yes	9.384	0.000	EPSD	GDSC;CCLE	9.358	Loss
CMGC_MAPK_ERK1_MAPK3_ST	Q9UQC2	GAB2	P27361	MAPK3	T294	T294P	294	Missense	central	0	yes	9.384	0.000	EPSD	GDSC;CCLE	9.358	Loss
CMGC_MAPK_ERK1_MAPK3_ST	P10828	THRB	P27361	MAPK3	S55	S54L	54	Missense	proximal	-1	no	16.674	16.585	EPSD	GDSC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P10828	THRB	P27361	MAPK3	S142	P141L	141	Missense	proximal	-1	no	10.118	10.023	PhosphoSitePlus	GDSC;CCLE	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q92797	SYMPK	P27361	MAPK3	S1243	T1246I	1246	Missense	distal	3	no	17.169	17.132	EPSD	GDSC;CCLE	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q92797	SYMPK	P27361	MAPK3	T1246	T1246I	1246	Missense	central	0	yes	9.525	0.000	EPSD	GDSC;CCLE	9.358	Loss
CMGC_MAPK_ERK1_MAPK3_ST	Q9NRF2	SH2B1	P27361	MAPK3	S88	R82Q	82	Missense	distal	-6	no	17.328	17.337	EPSD	GDSC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P53355	DAPK1	P27361	MAPK3	S734	P732A	732	Missense	proximal	-2	no	20.876	18.525	PhosphoSitePlus	GDSC;CCLE	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P53355	DAPK1	P27361	MAPK3	S734	T741A	741	Missense	distal	7	no	20.876	21.104	PhosphoSitePlus	GDSC;CCLE	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q8NET8	TRPV3	P27361	MAPK3	T264	A269T	269	Missense	distal	5	no	13.493	13.613	PhosphoSitePlus	GDSC;CCLE	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P41182	BCL6	P27361	MAPK3	S343	N342Y	342	Missense	proximal	-1	no	20.314	20.286	EPSD;PhosphoSitePlus	GDSC;CCLE	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P41182	BCL6	P27361	MAPK3	S404	S404P	404	Missense	central	0	yes	15.477	0.000	EPSD	GDSC;CCLE	9.358	Loss
CMGC_MAPK_ERK1_MAPK3_ST	P41182	BCL6	P27361	MAPK3	S404	Q397H	397	Missense	distal	-7	no	15.477	15.467	EPSD	GDSC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P41182	BCL6	P27361	MAPK3	S404	P405Q	405	Missense	proximal	1	no	15.477	7.533	EPSD	GDSC;CCLE	9.358	Loss
CMGC_MAPK_ERK1_MAPK3_ST	P41182	BCL6	P27361	MAPK3	S427	Q426E	426	Missense	proximal	-1	no	16.223	16.279	EPSD	GDSC;CCLE	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P41182	BCL6	P27361	MAPK3	S457	M454T	454	Missense	distal	-3	no	16.788	16.885	EPSD	GDSC;CCLE	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P41182	BCL6	P27361	MAPK3	S460	M454T	454	Missense	distal	-6	no	9.365	9.619	EPSD	GDSC;CCLE	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q13164	MAPK7	P27361	MAPK3	S707	M704V	704	Missense	distal	-3	no	15.393	15.448	EPSD	GDSC;CCLE	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q13164	MAPK7	P27361	MAPK3	S720	E723D	723	Missense	distal	3	no	9.594	9.596	EPSD	GDSC;CCLE	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q9H9Z2	LIN28A	P27361	MAPK3	T189	R192*	192	Missense	distal	3	no	12.129	12.050	EPSD	GDSC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q9H9Z2	LIN28A	P27361	MAPK3	T189	R192P	192	Missense	distal	3	no	12.129	12.155	EPSD	GDSC;CCLE	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q9H9Z2	LIN28A	P27361	MAPK3	T189	G186R	186	Missense	distal	-3	no	12.129	12.123	EPSD	GDSC;CCLE	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q9H9Z2	LIN28A	P27361	MAPK3	T189	R192G	192	Missense	distal	3	no	12.129	12.135	EPSD	GDSC;CCLE	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q12772	SREBF2	P27361	MAPK3	S101	T96A	96	Missense	distal	-5	no	16.091	16.008	EPSD	GDSC;CCLE	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P05787	KRT8	P27361	MAPK3	S74	L76R	76	Missense	proximal	2	no	16.819	16.830	EPSD	GDSC;CCLE	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P05787	KRT8	P27361	MAPK3	S451	T455A	455	Missense	distal	4	no	12.153	11.935	EPSD	GDSC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P05787	KRT8	P27361	MAPK3	S457	T455A	455	Missense	proximal	-2	no	9.641	8.276	EPSD	GDSC	9.358	Loss
CMGC_MAPK_ERK1_MAPK3_ST	P05787	KRT8	P27361	MAPK3	S477	D479N	479	Missense	proximal	2	no	11.362	11.357	EPSD	GDSC;CCLE	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P06401	PGR	P27361	MAPK3	S130	A133S	133	Missense	distal	3	no	15.019	15.062	EPSD	GDSC;CCLE	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P06401	PGR	P27361	MAPK3	S130	C134*	134	Missense	distal	4	no	15.019	14.956	EPSD	GDSC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P06401	PGR	P27361	MAPK3	S162	R167Q	167	Missense	distal	5	no	16.966	16.964	EPSD	GDSC;CCLE	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P06401	PGR	P27361	MAPK3	S328	E327G	327	Missense	proximal	-1	no	10.883	10.842	EPSD	GDSC;CCLE	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P06401	PGR	P27361	MAPK3	S345	A338P	338	Missense	distal	-7	no	15.926	15.814	EPSD	GDSC;CCLE	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P06401	PGR	P27361	MAPK3	S345	P342L	342	Missense	distal	-3	no	15.926	15.842	EPSD	GDSC;CCLE	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P06401	PGR	P27361	MAPK3	S400	E395G	395	Missense	distal	-5	no	13.499	13.490	EPSD	GDSC;CCLE	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q15596	NCOA2	P27361	MAPK3	T197	V204I	204	Missense	distal	7	no	10.003	10.083	EPSD	GDSC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q15596	NCOA2	P27361	MAPK3	S402	N401S	401	Missense	proximal	-1	no	16.657	16.706	EPSD	GDSC;CCLE	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q15596	NCOA2	P27361	MAPK3	T457	A464V	464	Missense	distal	7	no	13.288	13.260	EPSD	GDSC;CCLE	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q15596	NCOA2	P27361	MAPK3	S469	A464V	464	Missense	distal	-5	no	14.720	14.743	EPSD	GDSC;CCLE	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q15596	NCOA2	P27361	MAPK3	S484	M485L	485	Missense	proximal	1	no	5.031	9.673	EPSD	GDSC;CCLE	9.358	Gain
CMGC_MAPK_ERK1_MAPK3_ST	Q15596	NCOA2	P27361	MAPK3	S487	S487L	487	Missense	central	0	yes	14.608	0.000	EPSD	GDSC;CCLE	9.358	Loss
CMGC_MAPK_ERK1_MAPK3_ST	Q15596	NCOA2	P27361	MAPK3	S487	M485L	485	Missense	proximal	-2	no	14.608	15.978	EPSD	GDSC;CCLE	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q15596	NCOA2	P27361	MAPK3	S493	S487L	487	Missense	distal	-6	no	15.343	15.011	EPSD	GDSC;CCLE	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q15596	NCOA2	P27361	MAPK3	S671	P673R	673	Missense	proximal	2	no	9.373	9.362	EPSD	GDSC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q15596	NCOA2	P27361	MAPK3	S736	K738R	738	Missense	proximal	2	no	18.552	18.555	PhosphoSitePlus	GDSC;CCLE	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q15596	NCOA2	P27361	MAPK3	S895	P888S	888	Missense	distal	-7	no	18.373	18.335	EPSD	GDSC;CCLE	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q15596	NCOA2	P27361	MAPK3	S895	Q894*	894	Missense	proximal	-1	no	18.373	18.181	EPSD	GDSC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P17676	CEBPB	P27361	MAPK3	S325	L327Q	327	Missense	proximal	2	no	9.477	9.478	EPSD	GDSC;CCLE	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P17676	CEBPB	P27361	MAPK3	S341	P335T	335	Missense	distal	-6	no	9.418	9.334	EPSD	GDSC;CCLE	9.358	Loss
CMGC_MAPK_ERK1_MAPK3_ST	P36956	SREBF1	P27361	MAPK3	T105	P99T	99	Missense	distal	-6	no	13.759	13.675	EPSD	GDSC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P36956	SREBF1	P27361	MAPK3	S386	L387P	387	Missense	proximal	1	no	4.778	13.816	EPSD	GDSC	9.358	Gain
CMGC_MAPK_ERK1_MAPK3_ST	O60504	SORBS3	P27361	MAPK3	S24	R31P	31	Missense	distal	7	no	10.905	10.813	EPSD	GDSC;CCLE	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	O60504	SORBS3	P27361	MAPK3	S28	R31P	31	Missense	distal	3	no	9.957	9.984	EPSD	GDSC;CCLE	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	O60504	SORBS3	P27361	MAPK3	S28	R34W	34	Missense	distal	6	no	9.957	9.134	EPSD	GDSC	9.358	Loss
CMGC_MAPK_ERK1_MAPK3_ST	O60504	SORBS3	P27361	MAPK3	S28	G32A	32	Missense	distal	4	no	9.957	9.787	EPSD	GDSC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	O60504	SORBS3	P27361	MAPK3	S29	R31P	31	Missense	proximal	2	no	9.439	9.450	EPSD	GDSC;CCLE	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	O60504	SORBS3	P27361	MAPK3	S29	R34W	34	Missense	distal	5	no	9.439	8.971	EPSD	GDSC	9.358	Loss
CMGC_MAPK_ERK1_MAPK3_ST	O60504	SORBS3	P27361	MAPK3	S29	G32A	32	Missense	distal	3	no	9.439	9.411	EPSD	GDSC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	O60504	SORBS3	P27361	MAPK3	S30	R31P	31	Missense	proximal	1	no	8.082	17.582	EPSD	GDSC;CCLE	9.358	Gain
CMGC_MAPK_ERK1_MAPK3_ST	O60504	SORBS3	P27361	MAPK3	S217	A215T	215	Missense	proximal	-2	no	9.172	10.537	EPSD	GDSC	9.358	Gain
CMGC_MAPK_ERK1_MAPK3_ST	O60504	SORBS3	P27361	MAPK3	S339	A335T	335	Missense	distal	-4	no	15.206	15.280	EPSD	GDSC;CCLE	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	O60504	SORBS3	P27361	MAPK3	S339	S334F	334	Missense	distal	-5	no	15.206	15.072	EPSD	GDSC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	O60504	SORBS3	P27361	MAPK3	S339	R336P	336	Missense	distal	-3	no	15.206	15.253	EPSD	GDSC;CCLE	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	O60504	SORBS3	P27361	MAPK3	S373	A375T	375	Missense	proximal	2	no	14.892	14.919	EPSD	GDSC;CCLE	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	O60504	SORBS3	P27361	MAPK3	S373	S366N	366	Missense	distal	-7	no	14.892	14.959	EPSD	GDSC;CCLE	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	O60504	SORBS3	P27361	MAPK3	S395	Q392*	392	Missense	distal	-3	no	15.013	14.840	EPSD	GDSC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	O60504	SORBS3	P27361	MAPK3	S563	P564S	564	Missense	proximal	1	no	14.694	5.641	EPSD	GDSC;CCLE	9.358	Loss
CMGC_MAPK_ERK1_MAPK3_ST	O60504	SORBS3	P27361	MAPK3	S606	T609I	609	Missense	distal	3	no	16.076	16.038	EPSD	GDSC;CCLE	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	O60504	SORBS3	P27361	MAPK3	T615	T609I	609	Missense	distal	-6	no	15.479	15.249	EPSD	GDSC;CCLE	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P43364	MAGEA11	P27361	MAPK3	S208	E201G	201	Missense	distal	-7	no	15.720	15.726	EPSD	GDSC;CCLE	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P10242	MYB	P27361	MAPK3	S370	S363C	363	Missense	distal	-7	no	15.888	16.158	EPSD	GDSC;CCLE	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P35568	IRS1	P27361	MAPK3	S383	R381C	381	Missense	proximal	-2	no	16.168	14.052	EPSD	GDSC;CCLE	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P35568	IRS1	P27361	MAPK3	S383	A386S	386	Missense	distal	3	no	16.168	16.212	EPSD	GDSC;CCLE	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P35568	IRS1	P27361	MAPK3	S383	P376L	376	Missense	distal	-7	no	16.168	16.275	EPSD	GDSC;CCLE	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P35568	IRS1	P27361	MAPK3	S388	R381C	381	Missense	distal	-7	no	13.889	14.076	EPSD	GDSC;CCLE	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P35568	IRS1	P27361	MAPK3	S388	A386S	386	Missense	proximal	-2	no	13.889	15.164	EPSD	GDSC;CCLE	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P35568	IRS1	P27361	MAPK3	S404	R411*	411	Missense	distal	7	no	9.281	9.832	EPSD	GDSC	9.358	Gain
CMGC_MAPK_ERK1_MAPK3_ST	P35568	IRS1	P27361	MAPK3	T495	G488S	488	Missense	distal	-7	no	17.120	17.082	EPSD	GDSC;CCLE	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P35568	IRS1	P27361	MAPK3	S603	G597E	597	Missense	distal	-6	no	9.681	9.726	EPSD	GDSC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P35568	IRS1	P27361	MAPK3	S636	A642S	642	Missense	distal	6	no	16.332	16.857	EPSD	GDSC;CCLE	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P35568	IRS1	P27361	MAPK3	S736	P737S	737	Missense	proximal	1	no	15.159	6.105	EPSD	GDSC	9.358	Loss
CMGC_MAPK_ERK1_MAPK3_ST	P35568	IRS1	P27361	MAPK3	S1078	S1084R	1084	Missense	distal	6	no	14.980	14.738	EPSD	GDSC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P35568	IRS1	P27361	MAPK3	S1078	A1085D	1085	Missense	distal	7	no	14.980	14.740	EPSD	GDSC;CCLE	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P35568	IRS1	P27361	MAPK3	T1196	P1192L	1192	Missense	distal	-4	no	15.427	15.314	EPSD	GDSC;CCLE	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P35568	IRS1	P27361	MAPK3	T1196	P1202S	1202	Missense	distal	6	no	15.427	15.557	EPSD	GDSC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P35568	IRS1	P27361	MAPK3	S1217	S1218P	1218	Missense	proximal	1	no	9.061	18.115	EPSD	GDSC	9.358	Gain
CMGC_MAPK_ERK1_MAPK3_ST	P35568	IRS1	P27361	MAPK3	S1218	S1218P	1218	Missense	central	0	yes	10.887	0.000	EPSD	GDSC	9.358	Loss
CMGC_MAPK_ERK1_MAPK3_ST	P35568	IRS1	P27361	MAPK3	T1219	S1218P	1218	Missense	proximal	-1	no	10.236	10.241	EPSD	GDSC	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P35568	IRS1	P27361	MAPK3	S1222	S1218P	1218	Missense	distal	-4	no	12.032	12.005	EPSD	GDSC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P35568	IRS1	P27361	MAPK3	S1223	S1218P	1218	Missense	distal	-5	no	11.468	11.463	EPSD	GDSC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P35568	IRS1	P27361	MAPK3	S1227	S1233N	1233	Missense	distal	6	no	10.304	10.075	EPSD	GDSC;CCLE	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P46527	CDKN1B	P27361	MAPK3	S175	G177S	177	Missense	proximal	2	no	10.278	10.295	EPSD	GDSC;CCLE	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P46527	CDKN1B	P27361	MAPK3	S178	G177S	177	Missense	proximal	-1	no	20.295	20.361	EPSD	GDSC;CCLE	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q14934	NFATC4	P27361	MAPK3	S237	S237N	237	Missense	central	0	yes	16.625	0.000	EPSD	GDSC	9.358	Loss
CMGC_MAPK_ERK1_MAPK3_ST	P02686	MBP	P27361	MAPK3	S19	E13K	13	Missense	distal	-6	no	9.539	9.398	EPSD	GDSC;CCLE	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P02686	MBP	P27361	MAPK3	S19	T17K	17	Missense	proximal	-2	no	9.539	8.185	EPSD	GDSC	9.358	Loss
CMGC_MAPK_ERK1_MAPK3_ST	P02686	MBP	P27361	MAPK3	T229	P235L	235	Missense	distal	6	no	15.084	14.857	EPSD	GDSC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P02686	MBP	P27361	MAPK3	T232	P235L	235	Missense	distal	3	no	15.869	15.833	PhosphoSitePlus	GDSC	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q9UPT5	EXOC7	P27361	MAPK3	S250	V247I	247	Missense	distal	-3	no	18.233	18.194	PhosphoSitePlus	GDSC	9.358	Down-regulation
TKL_RIPK_RIPK3_ST	Q9UER7	DAXX	Q9Y572	RIPK3	S33	A32T	32	Missense	proximal	-1	no	27.419	27.537	EPSD	GDSC;CCLE	23.118	Up-regulation
TKL_RIPK_RIPK3_ST	Q9UER7	DAXX	Q9Y572	RIPK3	T181	S176A	176	Missense	distal	-5	no	25.707	25.156	EPSD	GDSC;CCLE	23.118	Down-regulation
TKL_RIPK_RIPK3_ST	Q9UER7	DAXX	Q9Y572	RIPK3	T181	R182H	182	Missense	proximal	1	no	25.707	25.637	EPSD	GDSC;CCLE	23.118	Down-regulation
TKL_RIPK_RIPK3_ST	Q9UER7	DAXX	Q9Y572	RIPK3	S429	C427Y	427	Missense	proximal	-2	no	22.867	23.956	EPSD	GDSC;CCLE	23.118	Gain
TKL_RIPK_RIPK3_ST	Q9UER7	DAXX	Q9Y572	RIPK3	S690	D687V	687	Missense	distal	-3	no	26.081	25.807	EPSD	GDSC	23.118	Down-regulation
TKL_RIPK_RIPK3_ST	Q9UER7	DAXX	Q9Y572	RIPK3	T719	V724M	724	Missense	distal	5	no	29.828	29.841	EPSD	GDSC	23.118	Up-regulation
TKL_RIPK_RIPK3_ST	Q9Y572	RIPK3	Q9Y572	RIPK3	T416	P421S	421	Missense	distal	5	no	25.166	23.547	EPSD	GDSC;CCLE	23.118	Down-regulation
TKL_RIPK_RIPK3_ST	P09622	DLD	Q9Y572	RIPK3	T135	H140R	140	Missense	distal	5	no	42.289	42.406	PhosphoSitePlus	GDSC;CCLE	23.118	Up-regulation
TKL_RIPK_RIPK3_ST	P09622	DLD	Q9Y572	RIPK3	S230	G229C	229	Missense	proximal	-1	no	25.363	24.328	EPSD	GDSC	23.118	Down-regulation
TKL_RIPK_RIPK3_ST	P09622	DLD	Q9Y572	RIPK3	T276	T282I	282	Missense	distal	6	no	25.073	25.157	EPSD	GDSC;CCLE	23.118	Up-regulation
STE_STE20_KHS_MAP4K1_ST	Q16584	MAP3K11	Q92918	MAP4K1	S419	A412V	412	Missense	distal	-7	no	2.622	2.462	EPSD	GDSC	2.024	Down-regulation
STE_STE20_KHS_MAP4K1_ST	Q16584	MAP3K11	Q92918	MAP4K1	T526	S524L	524	Missense	proximal	-2	no	4.012	3.703	EPSD	GDSC	2.024	Down-regulation
STE_STE20_KHS_MAP4K1_ST	Q16584	MAP3K11	Q92918	MAP4K1	S693	P692S	692	Missense	proximal	-1	no	2.901	3.300	EPSD	GDSC	2.024	Up-regulation
STE_STE20_KHS_MAP4K1_ST	Q9BXL7	CARD11	Q92918	MAP4K1	T532	A534D	534	Missense	proximal	2	no	2.288	1.584	EPSD	GDSC	2.024	Loss
STE_STE20_KHS_MAP4K1_ST	Q9BXL7	CARD11	Q92918	MAP4K1	T532	A534T	534	Missense	proximal	2	no	2.288	1.928	EPSD	GDSC	2.024	Loss
STE_STE20_KHS_MAP4K1_ST	Q9BXL7	CARD11	Q92918	MAP4K1	S535	G540V	540	Missense	distal	5	no	3.463	3.593	EPSD	GDSC;CCLE	2.024	Up-regulation
STE_STE20_KHS_MAP4K1_ST	Q9BXL7	CARD11	Q92918	MAP4K1	S535	A534D	534	Missense	proximal	-1	no	3.463	3.023	EPSD	GDSC	2.024	Down-regulation
STE_STE20_KHS_MAP4K1_ST	Q9BXL7	CARD11	Q92918	MAP4K1	S535	A534T	534	Missense	proximal	-1	no	3.463	3.011	EPSD	GDSC	2.024	Down-regulation
STE_STE20_KHS_MAP4K1_ST	Q9BXL7	CARD11	Q92918	MAP4K1	S556	R557H	557	Missense	proximal	1	no	7.521	7.223	PhosphoSitePlus;EPSD	GDSC	2.024	Down-regulation
STE_STE20_KHS_MAP4K1_ST	Q9BXL7	CARD11	Q92918	MAP4K1	S558	R557H	557	Missense	proximal	-1	no	8.222	7.954	EPSD;PhosphoSitePlus	GDSC	2.024	Down-regulation
STE_STE20_KHS_MAP4K1_ST	Q9BXL7	CARD11	Q92918	MAP4K1	T564	R557H	557	Missense	distal	-7	no	3.729	3.799	EPSD	GDSC	2.024	Up-regulation
STE_STE20_KHS_MAP4K1_ST	Q9BXL7	CARD11	Q92918	MAP4K1	S615	S610F	610	Missense	distal	-5	no	2.675	2.937	EPSD	GDSC;CCLE	2.024	Up-regulation
STE_STE20_KHS_MAP4K1_ST	Q9BXL7	CARD11	Q92918	MAP4K1	S615	H617R	617	Missense	proximal	2	no	2.675	2.761	EPSD	GDSC;CCLE	2.024	Up-regulation
STE_STE20_KHS_MAP4K1_ST	Q9BXL7	CARD11	Q92918	MAP4K1	S652	H658Q	658	Missense	distal	6	no	3.120	3.227	EPSD	GDSC;CCLE	2.024	Up-regulation
STE_STE20_KHS_MAP4K1_ST	Q9BXL7	CARD11	Q92918	MAP4K1	T880	D882V	882	Missense	proximal	2	no	2.799	2.932	EPSD	GDSC;CCLE	2.024	Up-regulation
STE_STE20_KHS_MAP4K1_ST	Q9BXL7	CARD11	Q92918	MAP4K1	S923	G928R	928	Missense	distal	5	no	2.838	2.905	EPSD	GDSC	2.024	Up-regulation
STE_STE20_KHS_MAP4K1_ST	Q9BXL7	CARD11	Q92918	MAP4K1	S923	S923L	923	Missense	central	0	yes	2.838	0.000	EPSD	GDSC;CCLE	2.024	Loss
STE_STE20_KHS_MAP4K1_ST	Q92918	MAP4K1	Q92918	MAP4K1	T165	I158T	158	Missense	distal	-7	no	9.210	9.207	PhosphoSitePlus	GDSC;CCLE	2.024	Down-regulation
STE_STE20_KHS_MAP4K1_ST	Q92918	MAP4K1	Q92918	MAP4K1	S430	V426F	426	Missense	distal	-4	no	2.575	2.528	EPSD	GDSC;CCLE	2.024	Down-regulation
STE_STE20_KHS_MAP4K1_ST	Q92918	MAP4K1	Q92918	MAP4K1	S430	R427Q	427	Missense	distal	-3	no	2.575	2.471	EPSD	GDSC	2.024	Down-regulation
STE_STE20_KHS_MAP4K1_ST	Q13094	LCP2	Q92918	MAP4K1	S246	R245C	245	Missense	proximal	-1	no	2.359	2.196	EPSD	GDSC;CCLE	2.024	Down-regulation
STE_STE20_KHS_MAP4K1_ST	Q13094	LCP2	Q92918	MAP4K1	S374	Y380H	380	Missense	distal	6	no	1.774	2.109	EPSD	GDSC;CCLE	2.024	Gain
STE_STE20_KHS_MAP4K1_ST	Q13094	LCP2	Q92918	MAP4K1	S376	Y380*	380	Missense	distal	4	no	9.054	8.890	PhosphoSitePlus	GDSC	2.024	Down-regulation
STE_STE20_KHS_MAP4K1_ST	Q13094	LCP2	Q92918	MAP4K1	S376	Y380H	380	Missense	distal	4	no	9.054	8.879	PhosphoSitePlus	GDSC;CCLE	2.024	Down-regulation
Other_CAMKK_CAMKK-Meta_CAMKK1_ST	Q16566	CAMK4	Q8N5S9	CAMKK1	S12	T18P	18	Missense	distal	6	no	2.421	2.410	EPSD;PhosphoSitePlus	GDSC	1.176	Down-regulation
Other_CAMKK_CAMKK-Meta_CAMKK1_ST	Q16566	CAMK4	Q8N5S9	CAMKK1	S13	T18P	18	Missense	distal	5	no	2.064	2.081	EPSD;PhosphoSitePlus	GDSC	1.176	Up-regulation
Other_CAMKK_CAMKK-Meta_CAMKK1_ST	Q16566	CAMK4	Q8N5S9	CAMKK1	T200	V196L	196	Missense	distal	-4	no	5.150	5.107	PhosphoSitePlus;EPSD	GDSC;CCLE	1.176	Down-regulation
CK1_CK1_CK1-D_CSNK1D_ST	O15055	PER2	P48730	CSNK1D	S56	G62W	62	Missense	distal	6	no	12.088	12.676	EPSD	GDSC;CCLE	11.915	Up-regulation
CK1_CK1_CK1-D_CSNK1D_ST	O15055	PER2	P48730	CSNK1D	S662	A664V	664	Missense	proximal	2	no	13.333	12.173	PhosphoSitePlus;EPSD	GDSC	11.915	Down-regulation
CK1_CK1_CK1-D_CSNK1D_ST	O15055	PER2	P48730	CSNK1D	S665	A664V	664	Missense	proximal	-1	no	14.104	13.557	EPSD;PhosphoSitePlus	GDSC	11.915	Down-regulation
CK1_CK1_CK1-D_CSNK1D_ST	O15055	PER2	P48730	CSNK1D	S668	A664V	664	Missense	distal	-4	no	15.530	14.763	EPSD;PhosphoSitePlus	GDSC	11.915	Down-regulation
CK1_CK1_CK1-D_CSNK1D_ST	O15055	PER2	P48730	CSNK1D	S671	A664V	664	Missense	distal	-7	no	12.258	10.180	EPSD	GDSC	11.915	Loss
CK1_CK1_CK1-D_CSNK1D_ST	O15055	PER2	P48730	CSNK1D	S771	R773*	773	Missense	proximal	2	no	15.052	12.677	EPSD	GDSC	11.915	Down-regulation
CK1_CK1_CK1-D_CSNK1D_ST	O15055	PER2	P48730	CSNK1D	T774	R773*	773	Missense	proximal	-1	no	12.777	11.256	EPSD	GDSC	11.915	Loss
CK1_CK1_CK1-D_CSNK1D_ST	O15055	PER2	P48730	CSNK1D	S810	G812E	812	Missense	proximal	2	no	13.908	14.057	EPSD	GDSC;CCLE	11.915	Up-regulation
CK1_CK1_CK1-D_CSNK1D_ST	O15055	PER2	P48730	CSNK1D	S1236	S1233N	1233	Missense	distal	-3	no	12.959	10.749	EPSD	GDSC	11.915	Loss
CK1_CK1_CK1-D_CSNK1D_ST	P27707	DCK	P48730	CSNK1D	T19	I24V	24	Missense	distal	5	no	16.185	15.901	EPSD	GDSC	11.915	Down-regulation
CK1_CK1_CK1-D_CSNK1D_ST	P27707	DCK	P48730	CSNK1D	S74	N80S	80	Missense	distal	6	no	14.916	15.359	EPSD;PhosphoSitePlus	GDSC	11.915	Up-regulation
CK1_CK1_CK1-D_CSNK1D_ST	P10636	MAPT	P48730	CSNK1D	S56	Q49H	49	Missense	distal	-7	no	16.124	14.603	EPSD	GDSC	11.915	Down-regulation
CK1_CK1_CK1-D_CSNK1D_ST	P10636	MAPT	P48730	CSNK1D	T71	P78T	78	Missense	distal	7	no	12.010	13.404	EPSD	GDSC;CCLE	11.915	Up-regulation
CK1_CK1_CK1-D_CSNK1D_ST	P10636	MAPT	P48730	CSNK1D	T123	E125G	125	Missense	proximal	2	no	12.455	12.307	EPSD	GDSC	11.915	Down-regulation
CK1_CK1_CK1-D_CSNK1D_ST	P10636	MAPT	P48730	CSNK1D	S171	D177V	177	Missense	distal	6	no	13.725	11.871	EPSD	GDSC	11.915	Loss
CK1_CK1_CK1-D_CSNK1D_ST	P10636	MAPT	P48730	CSNK1D	S228	R222H	222	Missense	distal	-6	no	15.102	13.759	EPSD	GDSC;CCLE	11.915	Down-regulation
CK1_CK1_CK1-D_CSNK1D_ST	P10636	MAPT	P48730	CSNK1D	S733	S739C	739	Missense	distal	6	no	15.204	10.218	EPSD	GDSC	11.915	Loss
CK1_CK1_CK1-D_CSNK1D_ST	Q99814	EPAS1	P48730	CSNK1D	S696	S703T	703	Missense	distal	7	no	11.469	13.724	EPSD	GDSC;CCLE	11.915	Gain
CK1_CK1_CK1-D_CSNK1D_ST	Q13148	TARDBP	P48730	CSNK1D	S92	V96M	96	Missense	distal	4	no	14.725	13.929	EPSD;PhosphoSitePlus	GDSC;CCLE	11.915	Down-regulation
CK1_CK1_CK1-D_CSNK1D_ST	Q13148	TARDBP	P48730	CSNK1D	S333	A326T	326	Missense	distal	-7	no	14.810	13.088	EPSD;PhosphoSitePlus	GDSC;CCLE	11.915	Down-regulation
CK1_CK1_CK1-D_CSNK1D_ST	Q13148	TARDBP	P48730	CSNK1D	S389	A388V	388	Missense	proximal	-1	no	12.633	12.087	EPSD;PhosphoSitePlus	GDSC;CCLE	11.915	Down-regulation
CK1_CK1_CK1-D_CSNK1D_ST	Q13148	TARDBP	P48730	CSNK1D	S393	G400D	400	Missense	distal	7	no	18.774	18.977	PhosphoSitePlus;EPSD	GDSC;CCLE	11.915	Up-regulation
CK1_CK1_CK1-D_CSNK1D_ST	Q13148	TARDBP	P48730	CSNK1D	S393	A388V	388	Missense	distal	-5	no	18.774	19.267	PhosphoSitePlus;EPSD	GDSC;CCLE	11.915	Up-regulation
CK1_CK1_CK1-D_CSNK1D_ST	Q13148	TARDBP	P48730	CSNK1D	S395	G400D	400	Missense	distal	5	no	17.157	16.700	EPSD;PhosphoSitePlus	GDSC;CCLE	11.915	Down-regulation
CK1_CK1_CK1-D_CSNK1D_ST	Q13148	TARDBP	P48730	CSNK1D	S395	A388V	388	Missense	distal	-7	no	17.157	15.079	EPSD;PhosphoSitePlus	GDSC;CCLE	11.915	Down-regulation
CK1_CK1_CK1-D_CSNK1D_ST	O14641	DVL2	P48730	CSNK1D	T39	V46L	46	Missense	distal	7	no	11.715	12.138	EPSD	GDSC;CCLE	11.915	Gain
CK1_CK1_CK1-D_CSNK1D_ST	O14641	DVL2	P48730	CSNK1D	S126	G127S	127	Missense	proximal	1	no	12.649	9.489	EPSD	GDSC;CCLE	11.915	Loss
CK1_CK1_CK1-D_CSNK1D_ST	O14641	DVL2	P48730	CSNK1D	S286	G279D	279	Missense	distal	-7	no	13.541	12.759	EPSD	GDSC;CCLE	11.915	Down-regulation
CK1_CK1_CK1-D_CSNK1D_ST	O14641	DVL2	P48730	CSNK1D	S358	P359S	359	Missense	proximal	1	no	15.495	13.176	EPSD	GDSC	11.915	Down-regulation
CK1_CK1_CK1-D_CSNK1D_ST	O14641	DVL2	P48730	CSNK1D	S358	P357S	357	Missense	proximal	-1	no	15.495	15.674	EPSD	GDSC;CCLE	11.915	Up-regulation
CK1_CK1_CK1-D_CSNK1D_ST	O14641	DVL2	P48730	CSNK1D	S425	A424T	424	Missense	proximal	-1	no	13.355	12.001	EPSD	GDSC;CCLE	11.915	Down-regulation
CK1_CK1_CK1-D_CSNK1D_ST	O14641	DVL2	P48730	CSNK1D	S425	V419I	419	Missense	distal	-6	no	13.355	12.451	EPSD	GDSC	11.915	Down-regulation
CK1_CK1_CK1-D_CSNK1D_ST	O14641	DVL2	P48730	CSNK1D	S589	R596Q	596	Missense	distal	7	no	13.242	14.513	EPSD	GDSC;CCLE	11.915	Up-regulation
CK1_CK1_CK1-D_CSNK1D_ST	O14641	DVL2	P48730	CSNK1D	S592	R596Q	596	Missense	distal	4	no	15.097	15.138	EPSD	GDSC;CCLE	11.915	Up-regulation
CK1_CK1_CK1-D_CSNK1D_ST	O14641	DVL2	P48730	CSNK1D	S594	R596Q	596	Missense	proximal	2	no	15.038	15.149	EPSD	GDSC;CCLE	11.915	Up-regulation
CK1_CK1_CK1-D_CSNK1D_ST	O14641	DVL2	P48730	CSNK1D	S597	R596Q	596	Missense	proximal	-1	no	14.692	14.978	EPSD	GDSC;CCLE	11.915	Up-regulation
CK1_CK1_CK1-D_CSNK1D_ST	O14641	DVL2	P48730	CSNK1D	S597	R603H	603	Missense	distal	6	no	14.692	15.950	EPSD	GDSC;CCLE	11.915	Up-regulation
CK1_CK1_CK1-D_CSNK1D_ST	P12830	CDH1	P48730	CSNK1D	S838	V832M	832	Missense	distal	-6	no	13.691	12.766	EPSD	GDSC	11.915	Down-regulation
CK1_CK1_CK1-D_CSNK1D_ST	P25054	APC	P48730	CSNK1D	S102	S98I	98	Missense	distal	-4	no	12.883	12.862	EPSD	GDSC;CCLE	11.915	Down-regulation
CK1_CK1_CK1-D_CSNK1D_ST	P25054	APC	P48730	CSNK1D	S111	M115V	115	Missense	distal	4	no	17.073	17.870	EPSD	GDSC;CCLE	11.915	Up-regulation
CK1_CK1_CK1-D_CSNK1D_ST	P25054	APC	P48730	CSNK1D	S846	E853*	853	Missense	distal	7	no	11.334	15.716	EPSD	GDSC	11.915	Gain
CK1_CK1_CK1-D_CSNK1D_ST	P25054	APC	P48730	CSNK1D	S1081	T1082S	1082	Missense	proximal	1	no	12.862	11.717	EPSD	GDSC;CCLE	11.915	Loss
CK1_CK1_CK1-D_CSNK1D_ST	P25054	APC	P48730	CSNK1D	S1128	Q1131*	1131	Missense	distal	3	no	14.298	11.636	EPSD	GDSC	11.915	Loss
CK1_CK1_CK1-D_CSNK1D_ST	P25054	APC	P48730	CSNK1D	S1128	S1126R	1126	Missense	proximal	-2	no	14.298	13.582	EPSD	GDSC;CCLE	11.915	Down-regulation
CK1_CK1_CK1-D_CSNK1D_ST	P25054	APC	P48730	CSNK1D	S1128	E1132Q	1132	Missense	distal	4	no	14.298	14.811	EPSD	GDSC;CCLE	11.915	Up-regulation
CK1_CK1_CK1-D_CSNK1D_ST	P25054	APC	P48730	CSNK1D	T1220	S1213P	1213	Missense	distal	-7	no	12.367	12.852	EPSD	GDSC;CCLE	11.915	Up-regulation
CK1_CK1_CK1-D_CSNK1D_ST	P25054	APC	P48730	CSNK1D	T1220	A1225S	1225	Missense	distal	5	no	12.367	12.754	EPSD	GDSC;CCLE	11.915	Up-regulation
CK1_CK1_CK1-D_CSNK1D_ST	P25054	APC	P48730	CSNK1D	T1220	E1216K	1216	Missense	distal	-4	no	12.367	12.217	EPSD	GDSC;CCLE	11.915	Down-regulation
CK1_CK1_CK1-D_CSNK1D_ST	P25054	APC	P48730	CSNK1D	S1222	A1225S	1225	Missense	distal	3	no	15.401	15.722	EPSD	GDSC;CCLE	11.915	Up-regulation
CK1_CK1_CK1-D_CSNK1D_ST	P25054	APC	P48730	CSNK1D	S1222	E1216K	1216	Missense	distal	-6	no	15.401	14.601	EPSD	GDSC;CCLE	11.915	Down-regulation
CK1_CK1_CK1-D_CSNK1D_ST	P25054	APC	P48730	CSNK1D	T1301	Q1303*	1303	Missense	proximal	2	no	12.823	10.338	EPSD	GDSC	11.915	Loss
CK1_CK1_CK1-D_CSNK1D_ST	P25054	APC	P48730	CSNK1D	S1343	Q1338*	1338	Missense	distal	-5	no	11.943	9.494	EPSD	GDSC	11.915	Loss
CK1_CK1_CK1-D_CSNK1D_ST	P25054	APC	P48730	CSNK1D	S1343	S1344*	1344	Missense	proximal	1	no	11.943	16.939	EPSD	GDSC	11.915	Up-regulation
CK1_CK1_CK1-D_CSNK1D_ST	P25054	APC	P48730	CSNK1D	S1343	G1339R	1339	Missense	distal	-4	no	11.943	11.727	EPSD	GDSC;CCLE	11.915	Loss
CK1_CK1_CK1-D_CSNK1D_ST	P25054	APC	P48730	CSNK1D	S1360	Q1367*	1367	Missense	distal	7	no	11.394	14.661	EPSD	GDSC	11.915	Gain
CK1_CK1_CK1-D_CSNK1D_ST	P25054	APC	P48730	CSNK1D	T1368	Q1367*	1367	Missense	proximal	-1	no	14.760	12.953	EPSD	GDSC	11.915	Down-regulation
CK1_CK1_CK1-D_CSNK1D_ST	P25054	APC	P48730	CSNK1D	S1505	G1499*	1499	Missense	distal	-6	no	14.387	12.485	EPSD;PhosphoSitePlus	GDSC	11.915	Down-regulation
CK1_CK1_CK1-D_CSNK1D_ST	P25054	APC	P48730	CSNK1D	T1556	Q1549*	1549	Missense	distal	-7	no	12.380	10.762	EPSD	GDSC	11.915	Loss
CK1_CK1_CK1-D_CSNK1D_ST	P25054	APC	P48730	CSNK1D	S1864	D1871Y	1871	Missense	distal	7	no	12.673	12.461	EPSD	GDSC;CCLE	11.915	Down-regulation
CK1_CK1_CK1-D_CSNK1D_ST	P25054	APC	P48730	CSNK1D	S2034	S2028T	2028	Missense	distal	-6	no	12.704	11.487	EPSD	GDSC;CCLE	11.915	Loss
CK1_CK1_CK1-D_CSNK1D_ST	P25054	APC	P48730	CSNK1D	S2064	G2070D	2070	Missense	distal	6	no	13.639	14.226	EPSD	GDSC;CCLE	11.915	Up-regulation
CK1_CK1_CK1-D_CSNK1D_ST	P25054	APC	P48730	CSNK1D	S2207	R2204*	2204	Missense	distal	-3	no	13.333	9.052	EPSD	GDSC	11.915	Loss
CK1_CK1_CK1-D_CSNK1D_ST	P25054	APC	P48730	CSNK1D	S2244	K2248*	2248	Missense	distal	4	no	13.176	14.282	EPSD	GDSC	11.915	Up-regulation
CK1_CK1_CK1-D_CSNK1D_ST	P25054	APC	P48730	CSNK1D	S2337	L2342F	2342	Missense	distal	5	no	13.073	13.852	EPSD	GDSC;CCLE	11.915	Up-regulation
CK1_CK1_CK1-D_CSNK1D_ST	P25054	APC	P48730	CSNK1D	S2337	R2333K	2333	Missense	distal	-4	no	13.073	13.328	EPSD	GDSC;CCLE	11.915	Up-regulation
CK1_CK1_CK1-D_CSNK1D_ST	P25054	APC	P48730	CSNK1D	S2464	F2462S	2462	Missense	proximal	-2	no	13.202	14.944	EPSD	GDSC;CCLE	11.915	Up-regulation
CK1_CK1_CK1-D_CSNK1D_ST	P25054	APC	P48730	CSNK1D	S2464	P2467L	2467	Missense	distal	3	no	13.202	14.182	EPSD	GDSC;CCLE	11.915	Up-regulation
CK1_CK1_CK1-D_CSNK1D_ST	P25054	APC	P48730	CSNK1D	S2580	S2575Y	2575	Missense	distal	-5	no	13.437	12.257	EPSD	GDSC	11.915	Down-regulation
CK1_CK1_CK1-D_CSNK1D_ST	P25054	APC	P48730	CSNK1D	S2581	S2575Y	2575	Missense	distal	-6	no	12.419	10.399	EPSD	GDSC	11.915	Loss
CK1_CK1_CK1-D_CSNK1D_ST	P25054	APC	P48730	CSNK1D	T2611	E2617V	2617	Missense	distal	6	no	11.987	9.089	EPSD	GDSC;CCLE	11.915	Loss
CK1_CK1_CK1-D_CSNK1D_ST	P25054	APC	P48730	CSNK1D	T2629	S2625I	2625	Missense	distal	-4	no	12.809	12.788	EPSD	GDSC;CCLE	11.915	Down-regulation
CK1_CK1_CK1-D_CSNK1D_ST	P25054	APC	P48730	CSNK1D	T2676	R2673G	2673	Missense	distal	-3	no	12.372	12.811	EPSD	GDSC;CCLE	11.915	Up-regulation
CK1_CK1_CK1-D_CSNK1D_ST	P25054	APC	P48730	CSNK1D	T2782	A2778V	2778	Missense	distal	-4	no	12.427	11.660	EPSD	GDSC	11.915	Loss
CK1_CK1_CK1-D_CSNK1D_ST	P04637	TP53	P48730	CSNK1D	S6	M1K	1	Missense	distal	-5	no	15.860	15.945	EPSD	GDSC	11.915	Up-regulation
CK1_CK1_CK1-D_CSNK1D_ST	P04637	TP53	P48730	CSNK1D	S37	Q38*	38	Missense	proximal	1	no	9.023	12.158	EPSD	GDSC	11.915	Gain
CK1_CK1_CK1-D_CSNK1D_ST	P04637	TP53	P48730	CSNK1D	S106	Y107*	107	Missense	proximal	1	no	7.282	12.170	EPSD	GDSC	11.915	Gain
CK1_CK1_CK1-D_CSNK1D_ST	P04637	TP53	P48730	CSNK1D	S127	Y126*	126	Missense	proximal	-1	no	12.589	12.043	EPSD	GDSC	11.915	Down-regulation
CK1_CK1_CK1-D_CSNK1D_ST	P04637	TP53	P48730	CSNK1D	S127	K120*	120	Missense	distal	-7	no	12.589	11.446	EPSD	GDSC	11.915	Loss
CK1_CK1_CK1-D_CSNK1D_ST	P49810	PSEN2	P48730	CSNK1D	T27	S30F	30	Missense	distal	3	no	15.278	14.119	EPSD	GDSC;CCLE	11.915	Down-regulation
CK1_CK1_CK1-D_CSNK1D_ST	P35222	CTNNB1	P48730	CSNK1D	T59	T59N	59	Missense	central	0	yes	14.261	0.000	EPSD	GDSC	11.915	Loss
CK1_CK1_CK1-D_CSNK1D_ST	P35222	CTNNB1	P48730	CSNK1D	S179	H176Y	176	Missense	distal	-3	no	13.351	13.785	EPSD	GDSC;CCLE	11.915	Up-regulation
CK1_CK1_CK1-D_CSNK1D_ST	P35222	CTNNB1	P48730	CSNK1D	T547	R549H	549	Missense	proximal	2	no	12.866	12.018	EPSD	GDSC;CCLE	11.915	Down-regulation
CK1_CK1_CK1-D_CSNK1D_ST	Q14511	NEDD9	P48730	CSNK1D	T126	G123D	123	Missense	distal	-3	no	11.809	12.791	EPSD	GDSC;CCLE	11.915	Gain
CK1_CK1_CK1-D_CSNK1D_ST	Q14511	NEDD9	P48730	CSNK1D	S298	S296N	296	Missense	proximal	-2	no	12.728	11.106	EPSD	GDSC;CCLE	11.915	Loss
CK1_CK1_CK1-D_CSNK1D_ST	Q14511	NEDD9	P48730	CSNK1D	S618	Q611K	611	Missense	distal	-7	no	14.820	14.345	EPSD	GDSC;CCLE	11.915	Down-regulation
CK1_CK1_CK1-D_CSNK1D_ST	Q14511	NEDD9	P48730	CSNK1D	S618	E622K	622	Missense	distal	4	no	14.820	15.288	EPSD	GDSC;CCLE	11.915	Up-regulation
CK1_CK1_CK1-D_CSNK1D_ST	Q14511	NEDD9	P48730	CSNK1D	S621	D628Y	628	Missense	distal	7	no	13.835	13.623	EPSD	GDSC;CCLE	11.915	Down-regulation
CK1_CK1_CK1-D_CSNK1D_ST	Q14511	NEDD9	P48730	CSNK1D	S621	E622K	622	Missense	proximal	1	no	13.835	10.454	EPSD	GDSC;CCLE	11.915	Loss
CK1_CK1_CK1-D_CSNK1D_ST	P46937	YAP1	P48730	CSNK1D	T154	R161*	161	Missense	distal	7	no	10.570	15.108	EPSD	GDSC	11.915	Gain
CK1_CK1_CK1-D_CSNK1D_ST	Q96T88	UHRF1	P48730	CSNK1D	S439	G440C	440	Missense	proximal	1	no	11.946	9.450	EPSD	GDSC	11.915	Loss
CK1_CK1_CK1-D_CSNK1D_ST	O43312	MTSS1	P48730	CSNK1D	S446	G447D	447	Missense	proximal	1	no	14.585	14.053	EPSD	GDSC;CCLE	11.915	Down-regulation
CK1_CK1_CK1-D_CSNK1D_ST	O43312	MTSS1	P48730	CSNK1D	S484	G486D	486	Missense	proximal	2	no	12.393	12.395	EPSD	GDSC	11.915	Up-regulation
CK1_CK1_CK1-D_CSNK1D_ST	Q9BZL6	PRKD2	P48730	CSNK1D	T247	S245T	245	Missense	proximal	-2	no	11.776	13.384	EPSD	GDSC;CCLE	11.915	Gain
CK1_CK1_CK1-D_CSNK1D_ST	Q9BZL6	PRKD2	P48730	CSNK1D	S344	G348V	348	Missense	distal	4	no	13.396	14.354	EPSD	GDSC;CCLE	11.915	Up-regulation
CK1_CK1_CK1-D_CSNK1D_ST	Q9BZL6	PRKD2	P48730	CSNK1D	S353	G348V	348	Missense	distal	-5	no	11.302	12.006	EPSD	GDSC;CCLE	11.915	Gain
CK1_CK1_CK1-D_CSNK1D_ST	P43629	KIR3DL1	P48730	CSNK1D	S246	R247Q	247	Missense	proximal	1	no	15.252	15.772	EPSD	GDSC	11.915	Up-regulation
CK1_CK1_CK1-D_CSNK1D_ST	P43629	KIR3DL1	P48730	CSNK1D	S246	R247W	247	Missense	proximal	1	no	15.252	15.329	EPSD	GDSC;CCLE	11.915	Up-regulation
CK1_CK1_CK1-D_CSNK1D_ST	P43629	KIR3DL1	P48730	CSNK1D	S246	V240A	240	Missense	distal	-6	no	15.252	15.565	EPSD	GDSC;CCLE	11.915	Up-regulation
CK1_CK1_CK1-D_CSNK1D_ST	P43629	KIR3DL1	P48730	CSNK1D	S246	S239I	239	Missense	distal	-7	no	15.252	14.946	EPSD	GDSC;CCLE	11.915	Down-regulation
CK1_CK1_CK1-D_CSNK1D_ST	Q9Y6Q9	NCOA3	P48730	CSNK1D	S453	Y459H	459	Missense	distal	6	no	11.574	12.758	EPSD	GDSC;CCLE	11.915	Gain
CK1_CK1_CK1-D_CSNK1D_ST	Q9Y6Q9	NCOA3	P48730	CSNK1D	S583	S582G	582	Missense	proximal	-1	no	12.872	12.812	EPSD	GDSC;CCLE	11.915	Down-regulation
CK1_CK1_CK1-D_CSNK1D_ST	Q9Y6Q9	NCOA3	P48730	CSNK1D	S589	S582G	582	Missense	distal	-7	no	13.105	13.760	EPSD	GDSC;CCLE	11.915	Up-regulation
CK1_CK1_CK1-D_CSNK1D_ST	Q9Y6Q9	NCOA3	P48730	CSNK1D	T638	P641S	641	Missense	distal	3	no	9.395	12.163	EPSD	GDSC;CCLE	11.915	Gain
CK1_CK1_CK1-D_CSNK1D_ST	Q9Y6Q9	NCOA3	P48730	CSNK1D	S652	S657F	657	Missense	distal	5	no	15.054	14.574	EPSD	GDSC;CCLE	11.915	Down-regulation
CK1_CK1_CK1-D_CSNK1D_ST	Q9Y6Q9	NCOA3	P48730	CSNK1D	S655	S657F	657	Missense	proximal	2	no	13.926	13.252	EPSD	GDSC;CCLE	11.915	Down-regulation
CK1_CK1_CK1-D_CSNK1D_ST	Q9Y6Q9	NCOA3	P48730	CSNK1D	T663	S657F	657	Missense	distal	-6	no	12.088	11.359	EPSD	GDSC;CCLE	11.915	Loss
CK1_CK1_CK1-D_CSNK1D_ST	Q9Y6Q9	NCOA3	P48730	CSNK1D	S857	Y852C	852	Missense	distal	-5	no	13.588	14.178	EPSD	GDSC;CCLE	11.915	Up-regulation
CK1_CK1_CK1-D_CSNK1D_ST	P30291	WEE1	P48730	CSNK1D	S242	P240L	240	Missense	proximal	-2	no	13.310	10.579	EPSD	GDSC;CCLE	11.915	Loss
CK1_CK1_CK1-D_CSNK1D_ST	P30291	WEE1	P48730	CSNK1D	S289	I286V	286	Missense	distal	-3	no	9.391	14.120	EPSD	GDSC	11.915	Gain
CK1_CK1_CK1-D_CSNK1D_ST	Q16665	HIF1A	P48730	CSNK1D	S31	S28Y	28	Missense	distal	-3	no	13.466	12.194	EPSD	GDSC	11.915	Down-regulation
CK1_CK1_CK1-D_CSNK1D_ST	Q16665	HIF1A	P48730	CSNK1D	S510	Q508*	508	Missense	proximal	-2	no	13.317	8.255	EPSD	GDSC	11.915	Loss
CK1_CK1_CK1-D_CSNK1D_ST	Q16665	HIF1A	P48730	CSNK1D	S515	Q508*	508	Missense	distal	-7	no	13.604	11.985	EPSD	GDSC	11.915	Down-regulation
CK1_CK1_CK1-D_CSNK1D_ST	Q16665	HIF1A	P48730	CSNK1D	S760	K759T	759	Missense	proximal	-1	no	11.939	11.328	EPSD	GDSC;CCLE	11.915	Loss
CK1_CK1_CK1-D_CSNK1D_ST	Q16665	HIF1A	P48730	CSNK1D	S761	K759T	759	Missense	proximal	-2	no	13.332	15.133	EPSD	GDSC;CCLE	11.915	Up-regulation
Atypical_PDHK_PDHK_PDK4_ST	P08559	PDHA1	Q16654	PDK4	T286	Q285R	285	Missense	proximal	-1	no	2.570	2.477	EPSD	GDSC;CCLE	1.272	Down-regulation
Atypical_PDHK_PDHK_PDK4_ST	P29803	PDHA2	Q16654	PDK4	S128	V121L	121	Missense	distal	-7	no	2.424	2.306	EPSD	GDSC	1.272	Down-regulation
Atypical_PDHK_PDHK_PDK4_ST	P29803	PDHA2	Q16654	PDK4	S128	R130P	130	Missense	proximal	2	no	2.424	2.286	EPSD	GDSC;CCLE	1.272	Down-regulation
Atypical_PDHK_PDHK_PDK4_ST	P29803	PDHA2	Q16654	PDK4	T231	E232K	232	Missense	proximal	1	no	1.976	1.998	EPSD	GDSC;CCLE	1.272	Up-regulation
Atypical_PDHK_PDHK_PDK4_ST	P29803	PDHA2	Q16654	PDK4	T284	P277H	277	Missense	distal	-7	no	2.392	2.304	EPSD	GDSC;CCLE	1.272	Down-regulation
Atypical_PDHK_PDHK_PDK4_ST	P29803	PDHA2	Q16654	PDK4	S291	V297F	297	Missense	distal	6	no	13.830	13.789	EPSD;PhosphoSitePlus	GDSC;CCLE	1.272	Down-regulation
Atypical_PDHK_PDHK_PDK4_ST	P29803	PDHA2	Q16654	PDK4	S298	V297F	297	Missense	proximal	-1	no	14.303	14.231	PhosphoSitePlus;EPSD	GDSC;CCLE	1.272	Down-regulation
Other_PLK_SAK_PLK4_ST	O00444	PLK4	O00444	PLK4	S22	N16D	16	Missense	distal	-6	no	540.424	529.479	PhosphoSitePlus;EPSD	GDSC;CCLE	416.076	Down-regulation
Other_PLK_SAK_PLK4_ST	O00444	PLK4	O00444	PLK4	S270	S269Y	269	Missense	proximal	-1	no	525.521	510.774	EPSD	GDSC;CCLE	416.076	Down-regulation
Other_PLK_SAK_PLK4_ST	O00444	PLK4	O00444	PLK4	S305	D308N	308	Missense	distal	3	no	601.221	595.856	EPSD;PhosphoSitePlus	GDSC;CCLE	416.076	Down-regulation
Other_PLK_SAK_PLK4_ST	P61160	ACTR2	O00444	PLK4	S66	D59N	59	Missense	distal	-7	no	424.516	429.775	EPSD	GDSC	416.076	Up-regulation
Other_PLK_SAK_PLK4_ST	Q15154	PCM1	O00444	PLK4	T462	S463L	463	Missense	proximal	1	no	340.987	429.357	EPSD	GDSC;CCLE	416.076	Gain
Other_PLK_SAK_PLK4_ST	Q15154	PCM1	O00444	PLK4	S634	E627K	627	Missense	distal	-7	no	419.661	404.002	EPSD	GDSC;CCLE	416.076	Loss
Other_PLK_SAK_PLK4_ST	Q15154	PCM1	O00444	PLK4	S866	G871V	871	Missense	distal	5	no	445.019	447.171	EPSD	GDSC	416.076	Up-regulation
Other_PLK_SAK_PLK4_ST	Q15154	PCM1	O00444	PLK4	T1557	T1558R	1558	Missense	proximal	1	no	491.695	365.473	EPSD	GDSC;CCLE	416.076	Loss
Other_PLK_SAK_PLK4_ST	Q15154	PCM1	O00444	PLK4	T1557	G1556S	1556	Missense	proximal	-1	no	491.695	501.884	EPSD	GDSC	416.076	Up-regulation
Other_PLK_SAK_PLK4_ST	O43303	CCP110	O00444	PLK4	T382	C386Y	386	Missense	distal	4	no	478.780	505.966	EPSD	GDSC;CCLE	416.076	Up-regulation
Other_PLK_SAK_PLK4_ST	O43303	CCP110	O00444	PLK4	T382	R377*	377	Missense	distal	-5	no	478.780	478.872	EPSD	GDSC	416.076	Up-regulation
Other_Aur_AURKC_ST	Q9NQS7	INCENP	Q9UQB9	AURKC	S72	V74A	74	Missense	proximal	2	no	20.122	19.980	EPSD	GDSC;CCLE	14.093	Down-regulation
Other_Aur_AURKC_ST	Q9NQS7	INCENP	Q9UQB9	AURKC	T207	P206A	206	Missense	proximal	-1	no	17.060	16.502	EPSD	GDSC;CCLE	14.093	Down-regulation
Other_Aur_AURKC_ST	Q9NQS7	INCENP	Q9UQB9	AURKC	S323	Q320H	320	Missense	distal	-3	no	13.268	14.984	EPSD	GDSC;CCLE	14.093	Gain
Other_Aur_AURKC_ST	Q9NQS7	INCENP	Q9UQB9	AURKC	S336	A335T	335	Missense	proximal	-1	no	18.620	19.521	EPSD	GDSC	14.093	Up-regulation
Other_Aur_AURKC_ST	Q9NQS7	INCENP	Q9UQB9	AURKC	S336	R338K	338	Missense	proximal	2	no	18.620	18.332	EPSD	GDSC;CCLE	14.093	Down-regulation
Other_Aur_AURKC_ST	Q9NQS7	INCENP	Q9UQB9	AURKC	S486	V488M	488	Missense	proximal	2	no	15.849	15.652	EPSD	GDSC	14.093	Down-regulation
Other_Aur_AURKC_ST	Q9NQS7	INCENP	Q9UQB9	AURKC	T524	K521N	521	Missense	distal	-3	no	19.996	19.064	EPSD	GDSC;CCLE	14.093	Down-regulation
Other_Aur_AURKC_ST	Q9NQS7	INCENP	Q9UQB9	AURKC	S894	P901L	901	Missense	distal	7	no	30.434	30.780	PhosphoSitePlus;EPSD	GDSC;CCLE	14.093	Up-regulation
Other_Aur_AURKC_ST	O15392	BIRC5	Q9UQB9	AURKC	S20	H17Y	17	Missense	distal	-3	no	28.038	26.666	PhosphoSitePlus	GDSC;CCLE	14.093	Down-regulation
Other_Aur_AURKC_ST	O75410	TACC1	Q9UQB9	AURKC	S91	A89T	89	Missense	proximal	-2	no	15.108	16.491	EPSD	GDSC;CCLE	14.093	Up-regulation
Other_Aur_AURKC_ST	O75410	TACC1	Q9UQB9	AURKC	S361	D356H	356	Missense	distal	-5	no	14.188	14.347	EPSD	GDSC;CCLE	14.093	Up-regulation
Other_Aur_AURKC_ST	O75410	TACC1	Q9UQB9	AURKC	T504	S497C	497	Missense	distal	-7	no	14.606	14.859	EPSD	GDSC;CCLE	14.093	Up-regulation
Other_Aur_AURKC_ST	O75410	TACC1	Q9UQB9	AURKC	S759	L766F	766	Missense	distal	7	no	15.038	15.163	EPSD	GDSC;CCLE	14.093	Up-regulation
Other_Aur_AURKC_ST	O75410	TACC1	Q9UQB9	AURKC	S759	T753P	753	Missense	distal	-6	no	15.038	14.946	EPSD	GDSC;CCLE	14.093	Down-regulation
STE_STE7_MEK7_MAP2K7_ST	P45984	MAPK9	O14733	MAP2K7	T183	V186L	186	Missense	distal	3	no	8.801	7.952	EPSD;PhosphoSitePlus	GDSC;CCLE	2.107	Down-regulation
STE_STE7_MEK7_MAP2K7_ST	P45984	MAPK9	O14733	MAP2K7	T183	T188S	188	Missense	distal	5	no	8.801	8.171	EPSD;PhosphoSitePlus	GDSC;CCLE	2.107	Down-regulation
STE_STE7_MEK7_MAP2K7_ST	P45984	MAPK9	O14733	MAP2K7	T404	T401A	401	Missense	distal	-3	no	6.076	6.131	EPSD;PhosphoSitePlus	GDSC	2.107	Up-regulation
STE_STE7_MEK7_MAP2K7_ST	P45984	MAPK9	O14733	MAP2K7	S407	T401A	401	Missense	distal	-6	no	5.531	5.630	PhosphoSitePlus;EPSD	GDSC	2.107	Up-regulation
STE_STE7_MEK7_MAP2K7_ST	P45983	MAPK8	O14733	MAP2K7	T183	G177*	177	Missense	distal	-6	no	9.246	9.197	PhosphoSitePlus;EPSD	GDSC	2.107	Down-regulation
TK_Src_Frk_FRK_Y	P60484	PTEN	P42685	FRK	Y336	R335*	335	Missense	proximal	-1	no	10.404	10.311	PhosphoSitePlus	GDSC	2.774	Down-regulation
Other_NAK_MPSK_STK16_ST	O75716	STK16	O75716	STK16	T185	Q187H	187	Missense	proximal	2	no	3.433	3.426	EPSD;PhosphoSitePlus	GDSC	1.527	Down-regulation
Other_NAK_MPSK_STK16_ST	O75716	STK16	O75716	STK16	T185	Q192*	192	Missense	distal	7	no	3.433	3.423	EPSD;PhosphoSitePlus	GDSC	1.527	Down-regulation
Other_NAK_MPSK_STK16_ST	O75716	STK16	O75716	STK16	T185	R181C	181	Missense	distal	-4	no	3.433	3.427	EPSD;PhosphoSitePlus	GDSC	1.527	Down-regulation
Other_NAK_MPSK_STK16_ST	O75716	STK16	O75716	STK16	S197	Q192*	192	Missense	distal	-5	no	3.400	3.398	PhosphoSitePlus;EPSD	GDSC	1.527	Down-regulation
Other_NAK_MPSK_STK16_ST	Q9Y295	DRG1	O75716	STK16	T220	A227V	227	Missense	distal	7	no	1.922	1.902	EPSD	GDSC;CCLE	1.527	Down-regulation
TK_EGFR_ERBB2_Y	O43157	PLXNB1	P04626	ERBB2	Y1708	V1703I	1703	Missense	distal	-5	no	6.099	6.010	PhosphoSitePlus;EPSD	GDSC;CCLE	2.878	Down-regulation
TK_EGFR_ERBB2_Y	P04626	ERBB2	P04626	ERBB2	Y1023	L1024M	1024	Missense	proximal	1	no	5.878	5.903	EPSD;PhosphoSitePlus	GDSC;CCLE	2.878	Up-regulation
TK_EGFR_ERBB2_Y	P00338	LDHA	P04626	ERBB2	Y10	D6H	6	Missense	distal	-4	no	3.820	3.807	PhosphoSitePlus	GDSC;CCLE	2.878	Down-regulation
AGC_DMPK_GEK_CDC42BPA_ST	Q5VT25	CDC42BPA	Q5VT25	CDC42BPA	S234	S234F	234	Missense	central	0	yes	5.474	0.000	EPSD;PhosphoSitePlus	GDSC	2.124	Loss
AGC_DMPK_GEK_CDC42BPA_ST	Q5VT25	CDC42BPA	Q5VT25	CDC42BPA	S234	S234Y	234	Missense	central	0	yes	5.474	0.000	EPSD;PhosphoSitePlus	GDSC	2.124	Loss
AGC_DMPK_GEK_CDC42BPA_ST	Q5VT25	CDC42BPA	Q5VT25	CDC42BPA	T240	S234F	234	Missense	distal	-6	no	5.481	5.435	EPSD;PhosphoSitePlus	GDSC	2.124	Down-regulation
AGC_DMPK_GEK_CDC42BPA_ST	Q5VT25	CDC42BPA	Q5VT25	CDC42BPA	T240	S234Y	234	Missense	distal	-6	no	5.481	5.463	EPSD;PhosphoSitePlus	GDSC	2.124	Down-regulation
AGC_DMPK_GEK_CDC42BPA_ST	Q5VT25	CDC42BPA	Q5VT25	CDC42BPA	S465	T466R	466	Missense	proximal	1	no	2.074	2.331	EPSD	GDSC;CCLE	2.124	Gain
AGC_DMPK_GEK_CDC42BPA_ST	Q5VT25	CDC42BPA	Q5VT25	CDC42BPA	S1713	S1706I	1706	Missense	distal	-7	no	2.090	2.237	EPSD	GDSC	2.124	Gain
AGC_DMPK_GEK_CDC42BPA_ST	P24844	MYL9	Q5VT25	CDC42BPA	T97	G96S	96	Missense	proximal	-1	no	2.207	2.092	EPSD	GDSC	2.124	Loss
STE_STE20_FRAY_OXSR1_ST	Q13621	SLC12A1	O95747	OXSR1	S91	A88V	88	Missense	distal	-3	no	24.831	22.254	EPSD	GDSC;CCLE	17.710	Down-regulation
STE_STE20_FRAY_OXSR1_ST	Q13621	SLC12A1	O95747	OXSR1	T95	A88V	88	Missense	distal	-7	no	50.566	50.557	EPSD;PhosphoSitePlus	GDSC;CCLE	17.710	Down-regulation
STE_STE20_FRAY_OXSR1_ST	Q13621	SLC12A1	O95747	OXSR1	T118	P124S	124	Missense	distal	6	no	46.996	47.043	EPSD;PhosphoSitePlus	GDSC;CCLE	17.710	Up-regulation
STE_STE20_FRAY_OXSR1_ST	Q13621	SLC12A1	O95747	OXSR1	S120	P124S	124	Missense	distal	4	no	46.596	46.480	EPSD;PhosphoSitePlus	GDSC;CCLE	17.710	Down-regulation
STE_STE20_FRAY_OXSR1_ST	Q13621	SLC12A1	O95747	OXSR1	S122	P124S	124	Missense	proximal	2	no	19.343	22.444	EPSD	GDSC;CCLE	17.710	Up-regulation
STE_STE20_FRAY_OXSR1_ST	P55017	SLC12A3	O95747	OXSR1	T55	T60M	60	Missense	distal	5	no	45.147	45.411	EPSD;PhosphoSitePlus	GDSC	17.710	Up-regulation
STE_STE20_FRAY_OXSR1_ST	P55017	SLC12A3	O95747	OXSR1	T60	T60M	60	Missense	central	0	yes	53.253	0.000	PhosphoSitePlus;EPSD	GDSC	17.710	Loss
STE_STE20_FRAY_OXSR1_ST	P55017	SLC12A3	O95747	OXSR1	T66	T60M	60	Missense	distal	-6	no	20.194	19.783	EPSD	GDSC	17.710	Down-regulation
TK_Src_SrcA_SRC_Y	Q14790	CASP8	P12931	SRC	Y380	S375P	375	Missense	distal	-5	no	21.749	21.647	EPSD;PhosphoSitePlus	GDSC	20.673	Down-regulation
TK_Src_SrcA_SRC_Y	P60484	PTEN	P12931	SRC	Y46	V53E	53	Missense	distal	7	no	22.622	22.564	EPSD;PhosphoSitePlus	GDSC	20.673	Down-regulation
TK_Src_SrcA_SRC_Y	P60484	PTEN	P12931	SRC	Y176	Y177*	177	Missense	proximal	1	no	21.281	17.617	EPSD	GDSC	20.673	Loss
TK_Src_SrcA_SRC_Y	P60484	PTEN	P12931	SRC	Y177	Y177*	177	Missense	central	0	yes	21.132	0.000	EPSD	GDSC	20.673	Loss
TK_Src_SrcA_SRC_Y	P60484	PTEN	P12931	SRC	Y240	R233*	233	Missense	distal	-7	no	21.485	20.346	EPSD;PhosphoSitePlus	GDSC	20.673	Loss
TK_Src_SrcA_SRC_Y	P17302	GJA1	P12931	SRC	Y265	S262P	262	Missense	distal	-3	no	20.925	19.808	PhosphoSitePlus;EPSD	GDSC;CCLE	20.673	Loss
TK_Src_SrcA_SRC_Y	P17302	GJA1	P12931	SRC	Y265	Q263*	263	Missense	proximal	-2	no	20.925	18.063	PhosphoSitePlus;EPSD	GDSC	20.673	Loss
TK_Src_SrcA_SRC_Y	Q13813	SPTAN1	P12931	SRC	Y976	Q979E	979	Missense	distal	3	no	20.548	21.142	EPSD	GDSC;CCLE	20.673	Gain
TK_Src_SrcA_SRC_Y	P35916	FLT4	P12931	SRC	Y1063	Y1068N	1068	Missense	distal	5	no	20.766	20.352	EPSD;PhosphoSitePlus	GDSC;CCLE	20.673	Loss
TK_Src_SrcA_SRC_Y	P35916	FLT4	P12931	SRC	Y1068	Y1068N	1068	Missense	central	0	yes	21.795	0.000	EPSD	GDSC;CCLE	20.673	Loss
TK_Src_SrcA_SRC_Y	Q9Y2W1	THRAP3	P12931	SRC	Y476	Y476C	476	Missense	central	0	yes	22.466	0.000	EPSD	GDSC;CCLE	20.673	Loss
TK_Src_SrcA_SRC_Y	Q9Y2W1	THRAP3	P12931	SRC	Y476	V475I	475	Missense	proximal	-1	no	22.466	22.091	EPSD	GDSC;CCLE	20.673	Down-regulation
TK_Src_SrcA_SRC_Y	Q9Y2W1	THRAP3	P12931	SRC	Y790	T796A	796	Missense	distal	6	no	21.316	21.330	EPSD	GDSC;CCLE	20.673	Up-regulation
TK_Src_SrcA_SRC_Y	Q9Y2W1	THRAP3	P12931	SRC	Y790	A792T	792	Missense	proximal	2	no	21.316	21.409	EPSD	GDSC;CCLE	20.673	Up-regulation
TK_Src_SrcA_SRC_Y	Q9Y2W1	THRAP3	P12931	SRC	Y795	T796A	796	Missense	proximal	1	no	20.766	21.220	EPSD	GDSC;CCLE	20.673	Up-regulation
TK_Src_SrcA_SRC_Y	Q9Y2W1	THRAP3	P12931	SRC	Y795	A792T	792	Missense	distal	-3	no	20.766	20.961	EPSD	GDSC;CCLE	20.673	Up-regulation
TK_Src_SrcA_SRC_Y	Q9H5V8	CDCP1	P12931	SRC	Y734	S731F	731	Missense	distal	-3	no	24.372	21.778	PhosphoSitePlus;EPSD	GDSC;CCLE	20.673	Down-regulation
TK_Src_SrcA_SRC_Y	Q9H5V8	CDCP1	P12931	SRC	Y806	Y806C	806	Missense	central	0	yes	22.731	0.000	EPSD	GDSC;CCLE	20.673	Loss
TK_Src_SrcA_SRC_Y	P41235	HNF4A	P12931	SRC	Y446	G451R	451	Missense	distal	5	no	20.896	20.714	EPSD	GDSC	20.673	Down-regulation
TK_Src_SrcA_SRC_Y	P41235	HNF4A	P12931	SRC	Y446	G451E	451	Missense	distal	5	no	20.896	20.739	EPSD	GDSC	20.673	Down-regulation
TK_Src_SrcA_SRC_Y	P25098	GRK2	P12931	SRC	Y506	R507C	507	Missense	proximal	1	no	25.336	24.032	EPSD	GDSC	20.673	Down-regulation
TK_Src_SrcA_SRC_Y	P29353	SHC1	P12931	SRC	Y349	Y349H	349	Missense	central	0	yes	24.617	0.000	EPSD;PhosphoSitePlus	GDSC;CCLE	20.673	Loss
TK_Src_SrcA_SRC_Y	P29353	SHC1	P12931	SRC	Y350	Y349H	349	Missense	proximal	-1	no	21.289	20.693	EPSD;PhosphoSitePlus	GDSC;CCLE	20.673	Down-regulation
TK_Src_SrcA_SRC_Y	Q12879	GRIN2A	P12931	SRC	Y1118	K1124T	1124	Missense	distal	6	no	21.911	21.874	EPSD	GDSC;CCLE	20.673	Down-regulation
TK_Src_SrcA_SRC_Y	Q12879	GRIN2A	P12931	SRC	Y1118	E1123D	1123	Missense	distal	5	no	21.911	21.704	EPSD	GDSC;CCLE	20.673	Down-regulation
TK_Src_SrcA_SRC_Y	Q12879	GRIN2A	P12931	SRC	Y1267	A1261T	1261	Missense	distal	-6	no	23.865	23.903	EPSD;PhosphoSitePlus	GDSC;CCLE	20.673	Up-regulation
TK_Src_SrcA_SRC_Y	Q12879	GRIN2A	P12931	SRC	Y1292	S1291F	1291	Missense	proximal	-1	no	21.705	21.183	EPSD	GDSC;CCLE	20.673	Down-regulation
TK_Src_SrcA_SRC_Y	Q12879	GRIN2A	P12931	SRC	Y1292	R1285M	1285	Missense	distal	-7	no	21.705	20.915	EPSD	GDSC;CCLE	20.673	Down-regulation
TK_Src_SrcA_SRC_Y	Q12879	GRIN2A	P12931	SRC	Y1423	M1429L	1429	Missense	distal	6	no	23.431	23.421	EPSD;PhosphoSitePlus	GDSC;CCLE	20.673	Down-regulation
TK_Src_SrcA_SRC_Y	P40763	STAT3	P12931	SRC	Y446	D453N	453	Missense	distal	7	no	21.778	21.776	EPSD	GDSC;CCLE	20.673	Down-regulation
TK_Src_SrcA_SRC_Y	P52732	KIF11	P12931	SRC	Y82	P88Q	88	Missense	distal	6	no	21.086	21.082	EPSD	GDSC;CCLE	20.673	Down-regulation
TK_Src_SrcA_SRC_Y	P31645	SLC6A4	P12931	SRC	Y47	N45S	45	Missense	proximal	-2	no	21.046	20.424	EPSD;PhosphoSitePlus	GDSC;CCLE	20.673	Loss
TK_Src_SrcA_SRC_Y	P31645	SLC6A4	P12931	SRC	Y47	S48L	48	Missense	proximal	1	no	21.046	19.500	EPSD;PhosphoSitePlus	GDSC;CCLE	20.673	Loss
TK_Src_SrcA_SRC_Y	Q7Z3C6	ATG9A	P12931	SRC	Y15	S18T	18	Missense	distal	3	no	21.348	21.436	EPSD;PhosphoSitePlus	GDSC;CCLE	20.673	Up-regulation
TK_Src_SrcA_SRC_Y	Q7Z3C6	ATG9A	P12931	SRC	Y209	L206V	206	Missense	distal	-3	no	20.973	21.784	EPSD	GDSC;CCLE	20.673	Up-regulation
TK_Src_SrcA_SRC_Y	Q8NER1	TRPV1	P12931	SRC	Y199	N192D	192	Missense	distal	-7	no	22.155	22.235	EPSD	GDSC;CCLE	20.673	Up-regulation
TK_Src_SrcA_SRC_Y	Q8NER1	TRPV1	P12931	SRC	Y199	A193S	193	Missense	distal	-6	no	22.155	22.244	EPSD	GDSC;CCLE	20.673	Up-regulation
TK_Src_SrcA_SRC_Y	P16885	PLCG2	P12931	SRC	Y720	E721K	721	Missense	proximal	1	no	21.309	18.914	EPSD	GDSC	20.673	Loss
TK_Src_SrcA_SRC_Y	P16885	PLCG2	P12931	SRC	Y1048	P1050Q	1050	Missense	proximal	2	no	22.202	22.327	EPSD	GDSC;CCLE	20.673	Up-regulation
TK_Src_SrcA_SRC_Y	P19022	CDH2	P12931	SRC	Y496	N500S	500	Missense	distal	4	no	21.765	21.733	EPSD	GDSC	20.673	Down-regulation
TK_Src_SrcA_SRC_Y	P19022	CDH2	P12931	SRC	Y496	P495T	495	Missense	proximal	-1	no	21.765	21.508	EPSD	GDSC;CCLE	20.673	Down-regulation
TK_Src_SrcA_SRC_Y	P19022	CDH2	P12931	SRC	Y785	E781K	781	Missense	distal	-4	no	21.935	20.765	EPSD	GDSC;CCLE	20.673	Down-regulation
TK_Src_SrcA_SRC_Y	P19022	CDH2	P12931	SRC	Y884	Q882K	882	Missense	proximal	-2	no	22.289	22.119	PhosphoSitePlus;EPSD	GDSC;CCLE	20.673	Down-regulation
TK_Src_SrcA_SRC_Y	Q96J92	WNK4	P12931	SRC	Y375	S371F	371	Missense	distal	-4	no	20.778	19.860	EPSD	GDSC;CCLE	20.673	Loss
TK_Src_SrcA_SRC_Y	Q03135	CAV1	P12931	SRC	Y25	N23S	23	Missense	proximal	-2	no	21.787	21.165	EPSD	GDSC	20.673	Down-regulation
TK_Src_SrcA_SRC_Y	Q13480	GAB1	P12931	SRC	Y259	Y259H	259	Missense	central	0	yes	20.690	0.000	EPSD;PhosphoSitePlus	GDSC	20.673	Loss
TK_Src_SrcA_SRC_Y	Q13480	GAB1	P12931	SRC	Y406	A411E	411	Missense	distal	5	no	21.248	21.342	EPSD	GDSC	20.673	Up-regulation
TK_Src_SrcA_SRC_Y	Q13480	GAB1	P12931	SRC	Y447	L443P	443	Missense	distal	-4	no	20.885	21.519	EPSD	GDSC;CCLE	20.673	Up-regulation
TK_Src_SrcA_SRC_Y	O43823	AKAP8	P12931	SRC	Y146	Y150C	150	Missense	distal	4	no	21.034	21.043	EPSD;PhosphoSitePlus	GDSC	20.673	Up-regulation
TK_Src_SrcA_SRC_Y	Q92945	KHSRP	P12931	SRC	Y149	D153G	153	Missense	distal	4	no	21.215	21.174	EPSD	GDSC;CCLE	20.673	Down-regulation
TK_Src_SrcA_SRC_Y	Q92945	KHSRP	P12931	SRC	Y149	E148*	148	Missense	proximal	-1	no	21.215	17.371	EPSD	GDSC	20.673	Loss
TK_Src_SrcA_SRC_Y	Q92945	KHSRP	P12931	SRC	Y674	A679V	679	Missense	distal	5	no	21.239	21.381	EPSD	GDSC;CCLE	20.673	Up-regulation
TK_Src_SrcA_SRC_Y	P26010	ITGB7	P12931	SRC	Y778	T783M	783	Missense	distal	5	no	20.987	21.208	EPSD	GDSC;CCLE	20.673	Up-regulation
TK_Src_SrcA_SRC_Y	P23246	SFPQ	P12931	SRC	Y293	E290D	290	Missense	distal	-3	no	21.695	21.740	EPSD	GDSC;CCLE	20.673	Up-regulation
TK_Src_SrcA_SRC_Y	P23246	SFPQ	P12931	SRC	Y488	R493L	493	Missense	distal	5	no	21.123	21.291	EPSD	GDSC;CCLE	20.673	Up-regulation
TK_Src_SrcA_SRC_Y	P23246	SFPQ	P12931	SRC	Y490	R493L	493	Missense	distal	3	no	19.055	20.744	EPSD	GDSC;CCLE	20.673	Gain
TK_Src_SrcA_SRC_Y	P23246	SFPQ	P12931	SRC	Y527	H528Y	528	Missense	proximal	1	no	21.869	22.915	EPSD	GDSC;CCLE	20.673	Up-regulation
TK_Src_SrcA_SRC_Y	P23246	SFPQ	P12931	SRC	Y597	M603T	603	Missense	distal	6	no	22.451	22.400	EPSD;PhosphoSitePlus	GDSC;CCLE	20.673	Down-regulation
TK_Src_SrcA_SRC_Y	O14641	DVL2	P12931	SRC	Y27	L20R	20	Missense	distal	-7	no	20.822	21.305	EPSD;PhosphoSitePlus	GDSC	20.673	Up-regulation
TK_Src_SrcA_SRC_Y	P15311	EZR	P12931	SRC	Y478	P476S	476	Missense	proximal	-2	no	25.069	24.283	PhosphoSitePlus;EPSD	GDSC;CCLE	20.673	Down-regulation
TK_Src_SrcA_SRC_Y	Q15139	PRKD1	P12931	SRC	Y463	S460R	460	Missense	distal	-3	no	21.351	20.278	EPSD;PhosphoSitePlus	GDSC	20.673	Loss
TK_Src_SrcA_SRC_Y	Q15139	PRKD1	P12931	SRC	Y463	P467T	467	Missense	distal	4	no	21.351	21.367	EPSD;PhosphoSitePlus	GDSC	20.673	Up-regulation
TK_Src_SrcA_SRC_Y	Q93052	LPP	P12931	SRC	Y244	S246L	246	Missense	proximal	2	no	22.155	21.091	PhosphoSitePlus;EPSD	GDSC	20.673	Down-regulation
TK_Src_SrcA_SRC_Y	Q93052	LPP	P12931	SRC	Y287	P291R	291	Missense	distal	4	no	21.800	21.796	EPSD	GDSC;CCLE	20.673	Down-regulation
TK_Src_SrcA_SRC_Y	Q93052	LPP	P12931	SRC	Y296	P291R	291	Missense	distal	-5	no	21.345	21.364	EPSD	GDSC;CCLE	20.673	Up-regulation
TK_Src_SrcA_SRC_Y	Q93052	LPP	P12931	SRC	Y297	P291R	291	Missense	distal	-6	no	22.001	21.910	EPSD	GDSC;CCLE	20.673	Down-regulation
TK_Src_SrcA_SRC_Y	Q93052	LPP	P12931	SRC	Y332	G336V	336	Missense	distal	4	no	20.717	20.713	EPSD	GDSC;CCLE	20.673	Down-regulation
TK_Src_SrcA_SRC_Y	Q93052	LPP	P12931	SRC	Y332	W326*	326	Missense	distal	-6	no	20.717	20.510	EPSD	GDSC	20.673	Loss
TK_Src_SrcA_SRC_Y	O15492	RGS16	P12931	SRC	Y177	Q183R	183	Missense	distal	6	no	21.421	21.405	PhosphoSitePlus;EPSD	GDSC;CCLE	20.673	Down-regulation
TK_Src_SrcA_SRC_Y	O15492	RGS16	P12931	SRC	Y177	D179A	179	Missense	proximal	2	no	21.421	21.530	PhosphoSitePlus;EPSD	GDSC;CCLE	20.673	Up-regulation
TK_Src_SrcA_SRC_Y	Q9UPT8	ZC3H4	P12931	SRC	Y364	E361G	361	Missense	distal	-3	no	22.518	21.915	EPSD	GDSC;CCLE	20.673	Down-regulation
TK_Src_SrcA_SRC_Y	Q9NWQ8	PAG1	P12931	SRC	Y181	V184M	184	Missense	distal	3	no	22.670	22.304	EPSD	GDSC;CCLE	20.673	Down-regulation
TK_Src_SrcA_SRC_Y	Q9NWQ8	PAG1	P12931	SRC	Y317	A315S	315	Missense	proximal	-2	no	20.641	21.007	PhosphoSitePlus	GDSC;CCLE	20.673	Gain
TK_Src_SrcA_SRC_Y	Q9NWQ8	PAG1	P12931	SRC	Y341	V336I	336	Missense	distal	-5	no	21.279	21.071	EPSD	GDSC;CCLE	20.673	Down-regulation
TK_Src_SrcA_SRC_Y	Q9NWQ8	PAG1	P12931	SRC	Y417	L423F	423	Missense	distal	6	no	21.965	21.964	EPSD	GDSC;CCLE	20.673	Down-regulation
TK_Src_SrcA_SRC_Y	Q9NWQ8	PAG1	P12931	SRC	Y417	K413E	413	Missense	distal	-4	no	21.965	23.135	EPSD	GDSC;CCLE	20.673	Up-regulation
TK_Src_SrcA_SRC_Y	Q16832	DDR2	P12931	SRC	Y481	P479H	479	Missense	proximal	-2	no	21.232	20.567	EPSD	GDSC;CCLE	20.673	Loss
TK_Src_SrcA_SRC_Y	Q16832	DDR2	P12931	SRC	Y481	Y481N	481	Missense	central	0	yes	21.232	0.000	EPSD	GDSC;CCLE	20.673	Loss
TK_Src_SrcA_SRC_Y	Q16832	DDR2	P12931	SRC	Y521	I526V	526	Missense	distal	5	no	20.680	20.630	EPSD	GDSC;CCLE	20.673	Loss
TK_Src_SrcA_SRC_Y	Q13322	GRB10	P12931	SRC	Y16	Y16H	16	Missense	central	0	yes	20.861	0.000	EPSD	GDSC	20.673	Loss
TK_Src_SrcA_SRC_Y	Q13322	GRB10	P12931	SRC	Y67	S71I	71	Missense	distal	4	no	21.316	21.298	PhosphoSitePlus	GDSC;CCLE	20.673	Down-regulation
TK_Src_SrcA_SRC_Y	Q9NYF8	BCLAF1	P12931	SRC	Y81	Q82*	82	Missense	proximal	1	no	22.817	19.134	EPSD;PhosphoSitePlus	GDSC	20.673	Loss
TK_Src_SrcA_SRC_Y	Q9NYF8	BCLAF1	P12931	SRC	Y81	G75*	75	Missense	distal	-6	no	22.817	22.345	EPSD;PhosphoSitePlus	GDSC	20.673	Down-regulation
TK_Src_SrcA_SRC_Y	Q9NYF8	BCLAF1	P12931	SRC	Y150	P149T	149	Missense	proximal	-1	no	21.992	21.735	EPSD;PhosphoSitePlus	GDSC	20.673	Down-regulation
TK_Src_SrcA_SRC_Y	Q9NYF8	BCLAF1	P12931	SRC	Y150	S143Y	143	Missense	distal	-7	no	21.992	21.590	EPSD;PhosphoSitePlus	GDSC;CCLE	20.673	Down-regulation
TK_Src_SrcA_SRC_Y	Q9NYF8	BCLAF1	P12931	SRC	Y284	N289S	289	Missense	distal	5	no	20.774	20.775	EPSD;PhosphoSitePlus	GDSC;CCLE	20.673	Up-regulation
TK_Src_SrcA_SRC_Y	Q9NYF8	BCLAF1	P12931	SRC	Y284	S281P	281	Missense	distal	-3	no	20.774	19.656	EPSD;PhosphoSitePlus	GDSC;CCLE	20.673	Loss
TK_Src_SrcA_SRC_Y	Q9NYF8	BCLAF1	P12931	SRC	Y284	Q288H	288	Missense	distal	4	no	20.774	20.766	EPSD;PhosphoSitePlus	GDSC;CCLE	20.673	Down-regulation
TK_Src_SrcA_SRC_Y	O15530	PDPK1	P12931	SRC	Y373	N378S	378	Missense	distal	5	no	23.167	23.168	EPSD;PhosphoSitePlus	GDSC;CCLE	20.673	Up-regulation
TK_Src_SrcA_SRC_Y	O15530	PDPK1	P12931	SRC	Y376	N378S	378	Missense	proximal	2	no	21.887	22.134	PhosphoSitePlus;EPSD	GDSC;CCLE	20.673	Up-regulation
TK_Src_SrcA_SRC_Y	Q15654	TRIP6	P12931	SRC	Y123	R117L	117	Missense	distal	-6	no	23.813	23.885	EPSD	GDSC;CCLE	20.673	Up-regulation
TK_Src_SrcA_SRC_Y	Q9Y613	FHOD1	P12931	SRC	Y176	S178N	178	Missense	proximal	2	no	20.923	20.676	EPSD	GDSC	20.673	Down-regulation
TK_Src_SrcA_SRC_Y	Q9Y613	FHOD1	P12931	SRC	Y439	I438T	438	Missense	proximal	-1	no	20.937	19.958	EPSD	GDSC;CCLE	20.673	Loss
TK_Src_SrcA_SRC_Y	P16662	UGT2B7	P12931	SRC	Y438	E440*	440	Missense	proximal	2	no	22.427	20.551	PhosphoSitePlus	GDSC	20.673	Loss
TK_Src_SrcA_SRC_Y	P16662	UGT2B7	P12931	SRC	Y438	V442I	442	Missense	distal	4	no	22.427	22.438	PhosphoSitePlus	GDSC	20.673	Up-regulation
TK_Src_SrcA_SRC_Y	P33151	CDH5	P12931	SRC	Y658	D659G	659	Missense	proximal	1	no	20.985	20.607	EPSD;PhosphoSitePlus	GDSC;CCLE	20.673	Loss
TK_Src_SrcA_SRC_Y	P29350	PTPN6	P12931	SRC	Y61	Y64C	64	Missense	distal	3	no	20.996	19.920	EPSD	GDSC;CCLE	20.673	Loss
TK_Src_SrcA_SRC_Y	P29350	PTPN6	P12931	SRC	Y214	Y208*	208	Missense	distal	-6	no	21.100	20.489	EPSD	GDSC	20.673	Loss
TK_Src_SrcA_SRC_Y	P29350	PTPN6	P12931	SRC	Y214	R210W	210	Missense	distal	-4	no	21.100	19.728	EPSD	GDSC;CCLE	20.673	Loss
TK_Src_SrcA_SRC_Y	P29350	PTPN6	P12931	SRC	Y536	S534L	534	Missense	proximal	-2	no	23.003	22.258	EPSD;PhosphoSitePlus	GDSC	20.673	Down-regulation
TK_Src_SrcA_SRC_Y	Q05397	PTK2	P12931	SRC	Y407	T406I	406	Missense	proximal	-1	no	23.970	24.949	EPSD;PhosphoSitePlus	GDSC;CCLE	20.673	Up-regulation
TK_Src_SrcA_SRC_Y	Q05397	PTK2	P12931	SRC	Y407	P410H	410	Missense	distal	3	no	23.970	23.373	EPSD;PhosphoSitePlus	GDSC;CCLE	20.673	Down-regulation
TK_Src_SrcA_SRC_Y	P35228	NOS2	P12931	SRC	Y46	V39A	39	Missense	distal	-7	no	20.974	20.922	EPSD	GDSC	20.673	Down-regulation
TK_Src_SrcA_SRC_Y	P35228	NOS2	P12931	SRC	Y46	Q45*	45	Missense	proximal	-1	no	20.974	17.535	EPSD	GDSC	20.673	Loss
TK_Src_SrcA_SRC_Y	P35228	NOS2	P12931	SRC	Y1055	K1053N	1053	Missense	proximal	-2	no	20.639	21.431	PhosphoSitePlus;EPSD	GDSC	20.673	Gain
TK_Src_SrcA_SRC_Y	O43490	PROM1	P12931	SRC	Y828	S824L	824	Missense	distal	-4	no	22.681	21.993	EPSD;PhosphoSitePlus	GDSC;CCLE	20.673	Down-regulation
TK_Src_SrcA_SRC_Y	Q9BZL6	PRKD2	P12931	SRC	Y717	A719S	719	Missense	proximal	2	no	21.371	21.723	EPSD	GDSC;CCLE	20.673	Up-regulation
TK_Src_SrcA_SRC_Y	Q9BXP5	SRRT	P12931	SRC	Y8	M1T	1	Missense	distal	-7	no	21.784	22.422	EPSD	GDSC	20.673	Up-regulation
TK_Src_SrcA_SRC_Y	Q96TC7	RMDN3	P12931	SRC	Y53	Y53C	53	Missense	central	0	yes	21.617	0.000	EPSD	GDSC;CCLE	20.673	Loss
TK_Src_SrcA_SRC_Y	P04626	ERBB2	P12931	SRC	Y1005	S1007*	1007	Missense	proximal	2	no	22.300	20.251	EPSD	GDSC	20.673	Loss
TK_Src_SrcA_SRC_Y	P04626	ERBB2	P12931	SRC	Y1023	L1024M	1024	Missense	proximal	1	no	22.106	22.245	EPSD	GDSC;CCLE	20.673	Up-regulation
TK_Src_SrcA_SRC_Y	P04626	ERBB2	P12931	SRC	Y1127	S1122T	1122	Missense	distal	-5	no	21.830	21.522	EPSD	GDSC	20.673	Down-regulation
TK_Src_SrcA_SRC_Y	Q14247	CTTN	P12931	SRC	Y486	E490K	490	Missense	distal	4	no	23.323	23.324	PhosphoSitePlus;EPSD	GDSC;CCLE	20.673	Up-regulation
TK_Src_SrcA_SRC_Y	P12830	CDH1	P12931	SRC	Y755	E762D	762	Missense	distal	7	no	21.893	21.855	EPSD	GDSC;CCLE	20.673	Down-regulation
TK_Src_SrcA_SRC_Y	P12830	CDH1	P12931	SRC	Y827	V832M	832	Missense	distal	5	no	23.234	23.528	EPSD	GDSC	20.673	Up-regulation
TK_Src_SrcA_SRC_Y	Q96P31	FCRL3	P12931	SRC	Y133	D136V	136	Missense	distal	3	no	21.037	21.787	EPSD	GDSC	20.673	Up-regulation
TK_Src_SrcA_SRC_Y	Q96P31	FCRL3	P12931	SRC	Y133	Q139H	139	Missense	distal	6	no	21.037	21.049	EPSD	GDSC;CCLE	20.673	Up-regulation
TK_Src_SrcA_SRC_Y	O15162	PLSCR1	P12931	SRC	Y69	N65K	65	Missense	distal	-4	no	22.480	21.616	PhosphoSitePlus;EPSD	GDSC	20.673	Down-regulation
TK_Src_SrcA_SRC_Y	P01889	HLA-B	P12931	SRC	Y344	A348E	348	Missense	distal	4	no	21.507	21.497	PhosphoSitePlus	GDSC;CCLE	20.673	Down-regulation
TK_Src_SrcA_SRC_Y	P01889	HLA-B	P12931	SRC	Y344	A347P	347	Missense	distal	3	no	21.507	22.202	PhosphoSitePlus	GDSC;CCLE	20.673	Up-regulation
TK_Src_SrcA_SRC_Y	Q13769	THOC5	P12931	SRC	Y37	S38N	38	Missense	proximal	1	no	22.081	21.182	EPSD	GDSC;CCLE	20.673	Down-regulation
TK_Src_SrcA_SRC_Y	P04083	ANXA1	P12931	SRC	Y156	I152N	152	Missense	distal	-4	no	20.129	21.669	EPSD	GDSC;CCLE	20.673	Gain
TK_Src_SrcA_SRC_Y	Q9NZQ3	NCKIPSD	P12931	SRC	Y227	S231N	231	Missense	distal	4	no	21.295	21.327	PhosphoSitePlus;EPSD	GDSC;CCLE	20.673	Up-regulation
TK_Src_SrcA_SRC_Y	Q9UKT4	FBXO5	P12931	SRC	Y318	H312R	312	Missense	distal	-6	no	21.250	21.283	EPSD	GDSC;CCLE	20.673	Up-regulation
TK_Src_SrcA_SRC_Y	P08238	HSP90AB1	P12931	SRC	Y192	R197Q	197	Missense	distal	5	no	20.852	20.877	EPSD	GDSC;CCLE	20.673	Up-regulation
TK_Src_SrcA_SRC_Y	P08238	HSP90AB1	P12931	SRC	Y301	G302*	302	Missense	proximal	1	no	23.893	20.209	PhosphoSitePlus	GDSC	20.673	Loss
TK_Src_SrcA_SRC_Y	P08238	HSP90AB1	P12931	SRC	Y305	G302*	302	Missense	distal	-3	no	22.401	17.856	EPSD	GDSC	20.673	Loss
TK_Src_SrcA_SRC_Y	Q969T9	WBP2	P12931	SRC	Y241	M242T	242	Missense	proximal	1	no	20.081	20.834	EPSD	GDSC;CCLE	20.673	Gain
TK_Src_SrcA_SRC_Y	P98175	RBM10	P12931	SRC	Y36	Y36F	36	Missense	central	0	yes	20.980	0.000	EPSD	GDSC;CCLE	20.673	Loss
TK_Src_SrcA_SRC_Y	P98175	RBM10	P12931	SRC	Y70	A72T	72	Missense	proximal	2	no	22.513	22.606	EPSD	GDSC;CCLE	20.673	Up-regulation
TK_Src_SrcA_SRC_Y	P98175	RBM10	P12931	SRC	Y561	S562N	562	Missense	proximal	1	no	21.534	20.635	EPSD	GDSC;CCLE	20.673	Loss
TK_Src_SrcA_SRC_Y	Q15642	TRIP10	P12931	SRC	Y190	R196G	196	Missense	distal	6	no	22.464	22.489	EPSD	GDSC;CCLE	20.673	Up-regulation
TK_Src_SrcA_SRC_Y	Q15642	TRIP10	P12931	SRC	Y190	E184K	184	Missense	distal	-6	no	22.464	22.451	EPSD	GDSC;CCLE	20.673	Down-regulation
TK_Src_SrcA_SRC_Y	P60953	CDC42	P12931	SRC	Y64	D65G	65	Missense	proximal	1	no	21.957	21.579	PhosphoSitePlus	GDSC;CCLE	20.673	Down-regulation
TK_Src_SrcA_SRC_Y	P52565	ARHGDIA	P12931	SRC	Y156	V162M	162	Missense	distal	6	no	23.928	23.956	EPSD;PhosphoSitePlus	GDSC;CCLE	20.673	Up-regulation
TK_Src_SrcA_SRC_Y	Q01844	EWSR1	P12931	SRC	Y278	S274R	274	Missense	distal	-4	no	21.957	22.227	PhosphoSitePlus	GDSC;CCLE	20.673	Up-regulation
TK_Src_SrcA_SRC_Y	P56945	BCAR1	P12931	SRC	Y128	G126S	126	Missense	proximal	-2	no	23.967	23.355	PhosphoSitePlus	GDSC	20.673	Down-regulation
TK_Src_SrcA_SRC_Y	P56945	BCAR1	P12931	SRC	Y165	A161T	161	Missense	distal	-4	no	21.792	22.067	EPSD	GDSC	20.673	Up-regulation
TK_Src_SrcA_SRC_Y	P56945	BCAR1	P12931	SRC	Y179	A175S	175	Missense	distal	-4	no	22.216	22.611	EPSD	GDSC;CCLE	20.673	Up-regulation
TK_Src_SrcA_SRC_Y	P56945	BCAR1	P12931	SRC	Y224	R217C	217	Missense	distal	-7	no	23.020	21.878	EPSD	GDSC;CCLE	20.673	Down-regulation
TK_Src_SrcA_SRC_Y	P56945	BCAR1	P12931	SRC	Y267	V274F	274	Missense	distal	7	no	25.176	25.138	EPSD	GDSC;CCLE	20.673	Down-regulation
TK_Src_SrcA_SRC_Y	P56945	BCAR1	P12931	SRC	Y267	S260G	260	Missense	distal	-7	no	25.176	24.803	EPSD	GDSC;CCLE	20.673	Down-regulation
TK_Src_SrcA_SRC_Y	P56945	BCAR1	P12931	SRC	Y287	R280*	280	Missense	distal	-7	no	25.071	23.932	EPSD	GDSC	20.673	Down-regulation
TK_Src_SrcA_SRC_Y	P56945	BCAR1	P12931	SRC	Y387	G384D	384	Missense	distal	-3	no	22.339	22.988	EPSD	GDSC	20.673	Up-regulation
TK_Src_SrcA_SRC_Y	P56945	BCAR1	P12931	SRC	Y410	S407N	407	Missense	distal	-3	no	24.087	24.047	EPSD	GDSC	20.673	Down-regulation
TK_Src_SrcA_SRC_Y	Q05655	PRKCD	P12931	SRC	Y514	Q521*	521	Missense	distal	7	no	21.007	21.156	EPSD	GDSC	20.673	Up-regulation
TK_Src_SrcA_SRC_Y	Q05655	PRKCD	P12931	SRC	Y567	T564M	564	Missense	distal	-3	no	21.050	19.821	EPSD	GDSC	20.673	Loss
TK_Src_SrcA_SRC_Y	Q05655	PRKCD	P12931	SRC	Y567	R569H	569	Missense	proximal	2	no	21.050	20.898	EPSD	GDSC	20.673	Down-regulation
TK_Src_SrcA_SRC_Y	P46527	CDKN1B	P12931	SRC	Y88	E86K	86	Missense	proximal	-2	no	21.012	19.652	EPSD;PhosphoSitePlus	GDSC;CCLE	20.673	Loss
TK_Src_SrcA_SRC_Y	P46527	CDKN1B	P12931	SRC	Y89	E86K	86	Missense	distal	-3	no	22.542	20.831	PhosphoSitePlus;EPSD	GDSC;CCLE	20.673	Down-regulation
TK_Src_SrcA_SRC_Y	Q96AC1	FERMT2	P12931	SRC	Y179	S186N	186	Missense	distal	7	no	23.819	23.786	EPSD	GDSC;CCLE	20.673	Down-regulation
TK_Src_SrcA_SRC_Y	Q96AE4	FUBP1	P12931	SRC	Y590	V597I	597	Missense	distal	7	no	21.333	21.308	EPSD	GDSC;CCLE	20.673	Down-regulation
TK_Src_SrcA_SRC_Y	Q9NPY3	CD93	P12931	SRC	Y628	S627N	627	Missense	proximal	-1	no	21.340	20.404	EPSD;PhosphoSitePlus	GDSC	20.673	Loss
TK_Src_SrcA_SRC_Y	Q14258	TRIM25	P12931	SRC	Y278	I277V	277	Missense	proximal	-1	no	20.310	20.685	PhosphoSitePlus	GDSC	20.673	Gain
TK_Src_SrcA_SRC_Y	O15056	SYNJ2	P12931	SRC	Y1136	G1131S	1131	Missense	distal	-5	no	20.704	20.772	EPSD	GDSC;CCLE	20.673	Up-regulation
TK_Src_SrcA_SRC_Y	Q99704	DOK1	P12931	SRC	Y337	Y341H	341	Missense	distal	4	no	20.863	20.884	EPSD	GDSC;CCLE	20.673	Up-regulation
TK_Src_SrcA_SRC_Y	Q9UBS0	RPS6KB2	P12931	SRC	Y45	E52K	52	Missense	distal	7	no	21.312	21.317	PhosphoSitePlus	GDSC;CCLE	20.673	Up-regulation
TK_Src_SrcA_SRC_Y	P51692	STAT5B	P12931	SRC	Y683	S690C	690	Missense	distal	7	no	20.658	20.769	EPSD	GDSC;CCLE	20.673	Gain
TK_Src_SrcA_SRC_Y	P63010	AP2B1	P12931	SRC	Y333	D340G	340	Missense	distal	7	no	21.042	21.103	EPSD	GDSC;CCLE	20.673	Up-regulation
TK_Src_SrcA_SRC_Y	P63000	RAC1	P12931	SRC	Y64	Y64H	64	Missense	central	0	yes	21.521	0.000	PhosphoSitePlus	GDSC;CCLE	20.673	Loss
TK_Src_SrcA_SRC_Y	P04049	RAF1	P12931	SRC	Y340	E343G	343	Missense	distal	3	no	24.009	24.287	PhosphoSitePlus;EPSD	GDSC;CCLE	20.673	Up-regulation
TK_Src_SrcA_SRC_Y	P04049	RAF1	P12931	SRC	Y341	E343G	343	Missense	proximal	2	no	22.588	21.633	EPSD;PhosphoSitePlus	GDSC;CCLE	20.673	Down-regulation
TK_Src_SrcA_SRC_Y	Q12913	PTPRJ	P12931	SRC	Y1094	T1091M	1091	Missense	distal	-3	no	21.844	20.615	EPSD	GDSC	20.673	Loss
TK_Src_SrcA_SRC_Y	Q12913	PTPRJ	P12931	SRC	Y1133	I1135V	1135	Missense	proximal	2	no	19.780	20.975	EPSD	GDSC	20.673	Gain
TK_Src_SrcA_SRC_Y	Q12913	PTPRJ	P12931	SRC	Y1268	I1270F	1270	Missense	proximal	2	no	21.912	21.829	EPSD	GDSC;CCLE	20.673	Down-regulation
TK_Src_SrcA_SRC_Y	Q96KG7	MEGF10	P12931	SRC	Y1075	A1070T	1070	Missense	distal	-5	no	24.403	24.193	EPSD	GDSC;CCLE	20.673	Down-regulation
TK_Src_SrcA_SRC_Y	Q9P219	CCDC88C	P12931	SRC	Y1272	E1271K	1271	Missense	proximal	-1	no	21.980	20.072	EPSD	GDSC;CCLE	20.673	Loss
TK_Src_SrcA_SRC_Y	P19404	NDUFV2	P12931	SRC	Y193	Y192C	192	Missense	proximal	-1	no	24.443	23.374	PhosphoSitePlus	GDSC;CCLE	20.673	Down-regulation
TK_Src_SrcA_SRC_Y	Q13936	CACNA1C	P12931	SRC	Y1142	E1139K	1139	Missense	distal	-3	no	20.948	19.237	EPSD	GDSC	20.673	Loss
TK_Src_SrcA_SRC_Y	P23743	DGKA	P12931	SRC	Y50	G45*	45	Missense	distal	-5	no	21.272	20.398	EPSD	GDSC	20.673	Loss
TK_Src_SrcA_SRC_Y	P23743	DGKA	P12931	SRC	Y669	L672F	672	Missense	distal	3	no	21.351	21.591	EPSD	GDSC;CCLE	20.673	Up-regulation
TK_Src_SrcA_SRC_Y	P18827	SDC1	P12931	SRC	Y299	G296D	296	Missense	distal	-3	no	20.945	21.594	EPSD	GDSC;CCLE	20.673	Up-regulation
TK_Src_SrcA_SRC_Y	P61586	RHOA	P12931	SRC	Y66	Y66D	66	Missense	central	0	yes	20.795	0.000	PhosphoSitePlus;EPSD	GDSC;CCLE	20.673	Loss
TK_Src_SrcA_SRC_Y	P61586	RHOA	P12931	SRC	Y66	A61S	61	Missense	distal	-5	no	20.795	20.893	PhosphoSitePlus;EPSD	GDSC;CCLE	20.673	Up-regulation
TK_Src_SrcA_SRC_Y	P07949	RET	P12931	SRC	Y809	E805*	805	Missense	distal	-4	no	20.746	17.522	EPSD	GDSC	20.673	Loss
TK_Src_SrcA_SRC_Y	P07949	RET	P12931	SRC	Y1096	P1091A	1091	Missense	distal	-5	no	22.266	22.270	EPSD	GDSC;CCLE	20.673	Up-regulation
TK_Src_SrcA_SRC_Y	Q92529	SHC3	P12931	SRC	Y406	G401V	401	Missense	distal	-5	no	25.471	25.442	EPSD	GDSC	20.673	Down-regulation
TK_Src_SrcA_SRC_Y	Q92529	SHC3	P12931	SRC	Y406	T408M	408	Missense	proximal	2	no	25.471	25.323	EPSD	GDSC	20.673	Down-regulation
TK_Src_SrcA_SRC_Y	Q92529	SHC3	P12931	SRC	Y406	G411E	411	Missense	distal	5	no	25.471	25.314	EPSD	GDSC;CCLE	20.673	Down-regulation
TK_Src_SrcA_SRC_Y	P50402	EMD	P12931	SRC	Y74	T67I	67	Missense	distal	-7	no	24.147	23.795	PhosphoSitePlus;EPSD	GDSC;CCLE	20.673	Down-regulation
TK_Src_SrcA_SRC_Y	P50402	EMD	P12931	SRC	Y94	F100S	100	Missense	distal	6	no	23.020	22.989	EPSD	GDSC;CCLE	20.673	Down-regulation
TK_Src_SrcA_SRC_Y	P50402	EMD	P12931	SRC	Y95	F100S	100	Missense	distal	5	no	25.691	25.442	EPSD;PhosphoSitePlus	GDSC;CCLE	20.673	Down-regulation
TK_Src_SrcA_SRC_Y	P50402	EMD	P12931	SRC	Y99	F100S	100	Missense	proximal	1	no	21.540	23.417	EPSD	GDSC;CCLE	20.673	Up-regulation
TK_Src_SrcA_SRC_Y	P50402	EMD	P12931	SRC	Y105	F100S	100	Missense	distal	-5	no	20.400	20.724	EPSD	GDSC;CCLE	20.673	Gain
TK_Src_SrcA_SRC_Y	Q9H2X6	HIPK2	P12931	SRC	Y44	G45D	45	Missense	proximal	1	no	20.406	20.784	EPSD	GDSC;CCLE	20.673	Gain
TK_Src_SrcA_SRC_Y	Q9Y446	PKP3	P12931	SRC	Y210	A206S	206	Missense	distal	-4	no	20.472	20.867	EPSD	GDSC;CCLE	20.673	Gain
TK_Src_SrcA_SRC_Y	Q9Y446	PKP3	P12931	SRC	Y390	D394N	394	Missense	distal	4	no	21.488	21.505	EPSD	GDSC;CCLE	20.673	Up-regulation
TK_Src_SrcA_SRC_Y	P31040	SDHA	P12931	SRC	Y169	K167R	167	Missense	proximal	-2	no	23.239	22.663	EPSD	GDSC;CCLE	20.673	Down-regulation
TK_Src_SrcA_SRC_Y	O43597	SPRY2	P12931	SRC	Y55	N53S	53	Missense	proximal	-2	no	22.341	21.718	PhosphoSitePlus	GDSC	20.673	Down-regulation
TK_Src_SrcA_SRC_Y	Q15746	MYLK	P12931	SRC	Y846	G847V	847	Missense	proximal	1	no	21.336	20.439	EPSD	GDSC;CCLE	20.673	Loss
TK_Src_SrcA_SRC_Y	P37840	SNCA	P12931	SRC	Y125	M127I	127	Missense	proximal	2	no	23.320	22.390	PhosphoSitePlus	GDSC	20.673	Down-regulation
TK_Src_SrcA_SRC_Y	P37840	SNCA	P12931	SRC	Y125	E130G	130	Missense	distal	5	no	23.320	23.477	PhosphoSitePlus	GDSC	20.673	Up-regulation
TK_Src_SrcA_SRC_Y	P57737	CORO7	P12931	SRC	Y615	T618A	618	Missense	distal	3	no	21.658	21.614	EPSD	GDSC;CCLE	20.673	Down-regulation
TK_Src_SrcA_SRC_Y	Q14289	PTK2B	P12931	SRC	Y402	C395Y	395	Missense	distal	-7	no	22.034	22.526	PhosphoSitePlus	GDSC;CCLE	20.673	Up-regulation
TK_Src_SrcA_SRC_Y	Q14289	PTK2B	P12931	SRC	Y402	A403T	403	Missense	proximal	1	no	22.034	21.580	PhosphoSitePlus	GDSC;CCLE	20.673	Down-regulation
TK_Src_SrcA_SRC_Y	Q14289	PTK2B	P12931	SRC	Y402	T409P	409	Missense	distal	7	no	22.034	22.084	PhosphoSitePlus	GDSC	20.673	Up-regulation
TK_Src_SrcA_SRC_Y	Q14289	PTK2B	P12931	SRC	Y440	Y440D	440	Missense	central	0	yes	22.476	0.000	EPSD	GDSC;CCLE	20.673	Loss
TK_Src_SrcA_SRC_Y	Q14289	PTK2B	P12931	SRC	Y881	M885L	885	Missense	distal	4	no	22.556	22.628	EPSD	GDSC;CCLE	20.673	Up-regulation
TK_Src_SrcA_SRC_Y	O14976	GAK	P12931	SRC	Y338	R345Q	345	Missense	distal	7	no	20.806	20.764	EPSD	GDSC	20.673	Down-regulation
TK_Src_SrcA_SRC_Y	O14976	GAK	P12931	SRC	Y338	E333Q	333	Missense	distal	-5	no	20.806	20.379	EPSD	GDSC;CCLE	20.673	Loss
TK_Src_SrcA_SRC_Y	O14976	GAK	P12931	SRC	Y371	P370L	370	Missense	proximal	-1	no	22.598	22.585	EPSD	GDSC	20.673	Down-regulation
TK_Src_SrcA_SRC_Y	P02786	TFRC	P12931	SRC	Y211	L212V	212	Missense	proximal	1	no	19.941	20.704	EPSD	GDSC	20.673	Gain
TK_Src_SrcA_SRC_Y	P02786	TFRC	P12931	SRC	Y402	F396C	396	Missense	distal	-6	no	22.148	21.747	EPSD	GDSC;CCLE	20.673	Down-regulation
TK_Src_SrcA_SRC_Y	A1X283	SH3PXD2B	P12931	SRC	Y42	A40V	40	Missense	proximal	-2	no	23.015	22.718	EPSD	GDSC;CCLE	20.673	Down-regulation
TK_Src_SrcA_SRC_Y	A1X283	SH3PXD2B	P12931	SRC	Y508	A506S	506	Missense	proximal	-2	no	23.045	23.412	PhosphoSitePlus	GDSC;CCLE	20.673	Up-regulation
TK_Src_SrcA_SRC_Y	A1X283	SH3PXD2B	P12931	SRC	Y855	A857S	857	Missense	proximal	2	no	21.160	21.512	EPSD	GDSC	20.673	Up-regulation
TK_Src_SrcA_SRC_Y	A1X283	SH3PXD2B	P12931	SRC	Y855	A859V	859	Missense	distal	4	no	21.160	21.133	EPSD	GDSC;CCLE	20.673	Down-regulation
TK_Src_SrcA_SRC_Y	A1X283	SH3PXD2B	P12931	SRC	Y855	G849S	849	Missense	distal	-6	no	21.160	21.303	EPSD	GDSC;CCLE	20.673	Up-regulation
TK_Src_SrcA_SRC_Y	Q3V6T2	CCDC88A	P12931	SRC	Y1153	E1147Q	1147	Missense	distal	-6	no	21.553	21.429	EPSD	GDSC	20.673	Down-regulation
TK_Src_SrcA_SRC_Y	P00338	LDHA	P12931	SRC	Y10	D6H	6	Missense	distal	-4	no	20.706	19.545	PhosphoSitePlus	GDSC;CCLE	20.673	Loss
TK_Src_SrcA_SRC_Y	P22681	CBL	P12931	SRC	Y455	N454K	454	Missense	proximal	-1	no	20.772	20.723	EPSD	GDSC;CCLE	20.673	Down-regulation
TK_Src_SrcA_SRC_Y	P22681	CBL	P12931	SRC	Y674	N671S	671	Missense	distal	-3	no	21.059	21.099	EPSD	GDSC;CCLE	20.673	Up-regulation
TK_Src_SrcA_SRC_Y	P22681	CBL	P12931	SRC	Y700	Y700C	700	Missense	central	0	yes	20.835	0.000	EPSD	GDSC;CCLE	20.673	Loss
TK_Src_SrcA_SRC_Y	P22681	CBL	P12931	SRC	Y731	Q738*	738	Missense	distal	7	no	22.875	23.024	EPSD;PhosphoSitePlus	GDSC	20.673	Up-regulation
TK_Src_SrcA_SRC_Y	P22681	CBL	P12931	SRC	Y774	D772E	772	Missense	proximal	-2	no	25.052	25.339	PhosphoSitePlus;EPSD	GDSC	20.673	Up-regulation
TK_Src_SrcA_SRC_Y	O14920	IKBKB	P12931	SRC	Y294	P296L	296	Missense	proximal	2	no	24.919	24.462	EPSD	GDSC	20.673	Down-regulation
TK_Src_SrcA_SRC_Y	Q07954	LRP1	P12931	SRC	Y1980	A1976E	1976	Missense	distal	-4	no	19.895	21.011	EPSD	GDSC;CCLE	20.673	Gain
TK_Src_SrcA_SRC_Y	Q07954	LRP1	P12931	SRC	Y4473	N4470K	4470	Missense	distal	-3	no	21.485	20.237	PhosphoSitePlus;EPSD	GDSC;CCLE	20.673	Loss
TK_Src_SrcA_SRC_Y	Q07954	LRP1	P12931	SRC	Y4473	G4479R	4479	Missense	distal	6	no	21.485	21.460	PhosphoSitePlus;EPSD	GDSC;CCLE	20.673	Down-regulation
TK_Src_SrcA_SRC_Y	Q16625	OCLN	P12931	SRC	Y342	T345M	345	Missense	distal	3	no	21.477	21.637	EPSD	GDSC	20.673	Up-regulation
TK_Src_SrcA_SRC_Y	Q16625	OCLN	P12931	SRC	Y342	Y337*	337	Missense	distal	-5	no	21.477	21.075	EPSD	GDSC	20.673	Down-regulation
TK_Src_SrcA_SRC_Y	Q16625	OCLN	P12931	SRC	Y398	D401N	401	Missense	distal	3	no	23.734	24.810	PhosphoSitePlus;EPSD	GDSC;CCLE	20.673	Up-regulation
TK_Src_SrcA_SRC_Y	Q16625	OCLN	P12931	SRC	Y398	Y402C	402	Missense	distal	4	no	23.734	23.743	PhosphoSitePlus;EPSD	GDSC;CCLE	20.673	Up-regulation
TK_Src_SrcA_SRC_Y	P16591	FER	P12931	SRC	Y200	I202V	202	Missense	proximal	2	no	20.027	21.221	EPSD	GDSC;CCLE	20.673	Gain
TK_Src_SrcA_SRC_Y	P16591	FER	P12931	SRC	Y714	V713M	713	Missense	proximal	-1	no	28.525	26.919	PhosphoSitePlus	GDSC;CCLE	20.673	Down-regulation
TK_Src_SrcA_SRC_Y	P16591	FER	P12931	SRC	Y714	R707L	707	Missense	distal	-7	no	28.525	28.041	PhosphoSitePlus	GDSC;CCLE	20.673	Down-regulation
TK_Src_SrcA_SRC_Y	Q00610	CLTC	P12931	SRC	Y1137	V1141I	1141	Missense	distal	4	no	21.484	21.495	EPSD	GDSC;CCLE	20.673	Up-regulation
TK_Src_SrcA_SRC_Y	Q00610	CLTC	P12931	SRC	Y1477	L1470I	1470	Missense	distal	-7	no	22.715	22.695	PhosphoSitePlus	GDSC;CCLE	20.673	Down-regulation
TK_Src_SrcA_SRC_Y	P04637	TP53	P12931	SRC	Y220	R213*	213	Missense	distal	-7	no	22.082	20.942	EPSD;PhosphoSitePlus	GDSC	20.673	Down-regulation
TK_Src_SrcA_SRC_Y	P04637	TP53	P12931	SRC	Y220	E224*	224	Missense	distal	4	no	22.082	22.027	EPSD;PhosphoSitePlus	GDSC	20.673	Down-regulation
TK_Src_SrcA_SRC_Y	Q13283	G3BP1	P12931	SRC	Y174	S180T	180	Missense	distal	6	no	21.073	21.063	EPSD	GDSC	20.673	Down-regulation
TK_Src_SrcA_SRC_Y	P35968	KDR	P12931	SRC	Y224	G220V	220	Missense	distal	-4	no	20.745	19.928	EPSD	GDSC	20.673	Loss
TK_Src_SrcA_SRC_Y	P35968	KDR	P12931	SRC	Y224	P230S	230	Missense	distal	6	no	20.745	20.729	EPSD	GDSC;CCLE	20.673	Down-regulation
TK_Src_SrcA_SRC_Y	P35968	KDR	P12931	SRC	Y1175	V1177L	1177	Missense	proximal	2	no	20.848	19.925	PhosphoSitePlus	GDSC;CCLE	20.673	Loss
TK_Src_SrcA_SRC_Y	P35968	KDR	P12931	SRC	Y1214	V1207E	1207	Missense	distal	-7	no	20.456	20.806	EPSD	GDSC;CCLE	20.673	Gain
TK_Src_SrcA_SRC_Y	Q8WWM7	ATXN2L	P12931	SRC	Y145	G142D	142	Missense	distal	-3	no	21.256	21.905	EPSD	GDSC;CCLE	20.673	Up-regulation
TK_Src_SrcA_SRC_Y	Q8WWM7	ATXN2L	P12931	SRC	Y145	G142C	142	Missense	distal	-3	no	21.256	18.715	EPSD	GDSC;CCLE	20.673	Loss
TK_Src_SrcA_SRC_Y	Q13017	ARHGAP5	P12931	SRC	Y306	G311V	311	Missense	distal	5	no	21.741	21.632	EPSD	GDSC;CCLE	20.673	Down-regulation
TK_Src_SrcA_SRC_Y	Q13017	ARHGAP5	P12931	SRC	Y1019	I1021V	1021	Missense	proximal	2	no	19.490	20.685	EPSD	GDSC	20.673	Gain
TK_Src_SrcA_SRC_Y	Q13017	ARHGAP5	P12931	SRC	Y1091	P1087S	1087	Missense	distal	-4	no	21.295	21.348	EPSD	GDSC;CCLE	20.673	Up-regulation
TK_Src_SrcA_SRC_Y	Q13017	ARHGAP5	P12931	SRC	Y1091	I1095L	1095	Missense	distal	4	no	21.295	21.320	EPSD	GDSC;CCLE	20.673	Up-regulation
TK_Src_SrcA_SRC_Y	Q13017	ARHGAP5	P12931	SRC	Y1091	I1098V	1098	Missense	distal	7	no	21.295	21.321	EPSD	GDSC	20.673	Up-regulation
TK_Src_SrcA_SRC_Y	Q13017	ARHGAP5	P12931	SRC	Y1091	S1088L	1088	Missense	distal	-3	no	21.295	19.027	EPSD	GDSC;CCLE	20.673	Loss
TK_Src_SrcA_SRC_Y	P49023	PXN	P12931	SRC	Y88	S83F	83	Missense	distal	-5	no	24.784	24.461	PhosphoSitePlus	GDSC	20.673	Down-regulation
TK_Src_SrcA_SRC_Y	P49023	PXN	P12931	SRC	Y88	V87E	87	Missense	proximal	-1	no	24.784	24.260	PhosphoSitePlus	GDSC	20.673	Down-regulation
TK_Src_SrcA_SRC_Y	P49023	PXN	P12931	SRC	Y181	S188R	188	Missense	distal	7	no	22.194	22.232	EPSD	GDSC	20.673	Up-regulation
TK_Src_SrcA_SRC_Y	P12956	XRCC6	P12931	SRC	Y322	I327V	327	Missense	distal	5	no	21.247	21.197	EPSD	GDSC;CCLE	20.673	Down-regulation
TK_Src_SrcA_SRC_Y	Q6UN15	FIP1L1	P12931	SRC	Y426	N428K	428	Missense	proximal	2	no	21.351	20.256	EPSD	GDSC	20.673	Loss
TK_Src_SrcA_SRC_Y	Q6UN15	FIP1L1	P12931	SRC	Y426	G427D	427	Missense	proximal	1	no	21.351	21.729	EPSD	GDSC;CCLE	20.673	Up-regulation
TK_Src_SrcA_SRC_Y	Q6UN15	FIP1L1	P12931	SRC	Y426	P432L	432	Missense	distal	6	no	21.351	21.367	EPSD	GDSC;CCLE	20.673	Up-regulation
TK_Src_SrcA_SRC_Y	P08727	KRT19	P12931	SRC	Y130	T132M	132	Missense	proximal	2	no	23.627	23.479	EPSD	GDSC;CCLE	20.673	Down-regulation
TK_Src_SrcA_SRC_Y	P08727	KRT19	P12931	SRC	Y131	R138Q	138	Missense	distal	7	no	23.221	23.178	EPSD	GDSC	20.673	Down-regulation
TK_Src_SrcA_SRC_Y	P08727	KRT19	P12931	SRC	Y131	T132M	132	Missense	proximal	1	no	23.221	22.468	EPSD	GDSC;CCLE	20.673	Down-regulation
TK_Src_SrcA_SRC_Y	P08727	KRT19	P12931	SRC	Y256	L249P	249	Missense	distal	-7	no	20.885	21.000	EPSD	GDSC	20.673	Up-regulation
TK_Src_SrcA_SRC_Y	P08727	KRT19	P12931	SRC	Y256	Y256H	256	Missense	central	0	yes	20.885	0.000	EPSD	GDSC;CCLE	20.673	Loss
TK_Src_SrcA_SRC_Y	P08727	KRT19	P12931	SRC	Y391	K398E	398	Missense	distal	7	no	22.099	22.095	PhosphoSitePlus	GDSC;CCLE	20.673	Down-regulation
TK_Src_SrcA_SRC_Y	Q14721	KCNB1	P12931	SRC	Y128	L129Q	129	Missense	proximal	1	no	21.700	23.359	PhosphoSitePlus	GDSC;CCLE	20.673	Up-regulation
TK_Src_SrcA_SRC_Y	Q14721	KCNB1	P12931	SRC	Y128	S131Y	131	Missense	distal	3	no	21.700	21.940	PhosphoSitePlus	GDSC;CCLE	20.673	Up-regulation
TK_Src_SrcA_SRC_Y	Q14721	KCNB1	P12931	SRC	Y128	G123C	123	Missense	distal	-5	no	21.700	20.965	PhosphoSitePlus	GDSC;CCLE	20.673	Down-regulation
TK_Src_SrcA_SRC_Y	P11511	CYP19A1	P12931	SRC	Y361	I360F	360	Missense	proximal	-1	no	22.879	21.284	PhosphoSitePlus	GDSC;CCLE	20.673	Down-regulation
TK_Src_SrcA_SRC_Y	P11511	CYP19A1	P12931	SRC	Y361	M356I	356	Missense	distal	-5	no	22.879	22.989	PhosphoSitePlus	GDSC;CCLE	20.673	Up-regulation
TK_Src_SrcA_SRC_Y	P10636	MAPT	P12931	SRC	Y18	T17M	17	Missense	proximal	-1	no	21.842	21.590	PhosphoSitePlus	GDSC	20.673	Down-regulation
TK_Src_SrcA_SRC_Y	Q9NR80	ARHGEF4	P12931	SRC	Y175	H174R	174	Missense	proximal	-1	no	22.527	20.631	EPSD	GDSC;CCLE	20.673	Loss
CMGC_CDK_CDK2_CDK3_ST	Q5TKA1	LIN9	Q00526	CDK3	S321	L317S	317	Missense	distal	-4	no	7.880	9.249	EPSD	GDSC	5.767	Up-regulation
CMGC_CDK_CDK2_CDK3_ST	Q14934	NFATC4	Q00526	CDK3	S237	S237N	237	Missense	central	0	yes	9.001	0.000	EPSD	GDSC	5.767	Loss
CMGC_CDK_CDK2_CDK3_ST	P03372	ESR1	Q00526	CDK3	S294	K299N	299	Missense	distal	5	no	9.470	9.545	EPSD	GDSC;CCLE	5.767	Up-regulation
CMGC_CDK_CDK2_CDK3_ST	P03372	ESR1	Q00526	CDK3	S294	I298V	298	Missense	distal	4	no	9.470	9.616	EPSD	GDSC	5.767	Up-regulation
CMGC_CDK_CDK2_CDK3_ST	P46531	NOTCH1	Q00526	CDK3	T2132	P2133S	2133	Missense	proximal	1	no	8.693	3.629	EPSD	GDSC	5.767	Loss
CMGC_CDK_CDK2_CDK3_ST	P46531	NOTCH1	Q00526	CDK3	S2136	P2133S	2133	Missense	distal	-3	no	8.121	8.160	EPSD	GDSC	5.767	Up-regulation
CMGC_CDK_CDK2_CDK3_ST	P46531	NOTCH1	Q00526	CDK3	S2163	V2158I	2158	Missense	distal	-5	no	6.163	6.794	EPSD	GDSC;CCLE	5.767	Up-regulation
CMGC_CDK_CDK2_CDK3_ST	P46531	NOTCH1	Q00526	CDK3	S2215	P2216L	2216	Missense	proximal	1	no	10.376	3.631	EPSD	GDSC;CCLE	5.767	Loss
CMGC_CDK_CDK2_CDK3_ST	P46531	NOTCH1	Q00526	CDK3	S2221	P2216L	2216	Missense	distal	-5	no	11.378	12.377	EPSD	GDSC;CCLE	5.767	Up-regulation
CMGC_CDK_CDK2_CDK3_ST	P05412	JUN	Q00526	CDK3	T91	H87R	87	Missense	distal	-4	no	8.463	8.083	EPSD	GDSC;CCLE	5.767	Down-regulation
CMGC_CDK_CDK2_CDK3_ST	P05412	JUN	Q00526	CDK3	T93	H87R	87	Missense	distal	-6	no	8.816	8.962	EPSD	GDSC;CCLE	5.767	Up-regulation
CMGC_CDK_CDK2_CDK3_ST	P18846	ATF1	Q00526	CDK3	T184	R182L	182	Missense	proximal	-2	no	9.924	9.916	EPSD	GDSC;CCLE	5.767	Down-regulation
CMGC_CDK_CDK2_CDK3_ST	Q12800	TFCP2	Q00526	CDK3	S309	N311S	311	Missense	proximal	2	no	14.086	14.306	PhosphoSitePlus	GDSC;CCLE	5.767	Up-regulation
CMGC_CDK_CDK2_CDK3_ST	Q8TDN4	CABLES1	Q00526	CDK3	S418	T419A	419	Missense	proximal	1	no	5.303	6.102	EPSD	GDSC;CCLE	5.767	Gain
CMGC_CDK_CDK2_CDK3_ST	Q8TDN4	CABLES1	Q00526	CDK3	S420	T419A	419	Missense	proximal	-1	no	5.942	5.941	EPSD	GDSC;CCLE	5.767	Down-regulation
CMGC_CDK_CDK2_CDK3_ST	P06400	RB1	Q00526	CDK3	S567	W563*	563	Missense	distal	-4	no	7.495	7.482	EPSD	GDSC	5.767	Down-regulation
CMGC_CDK_CDK2_CDK3_ST	P06400	RB1	Q00526	CDK3	S567	S567*	567	Missense	central	0	yes	7.495	0.000	EPSD	GDSC	5.767	Loss
CMGC_CDK_CDK2_CDK3_ST	P06400	RB1	Q00526	CDK3	S608	T601S	601	Missense	distal	-7	no	6.784	6.526	EPSD	GDSC;CCLE	5.767	Down-regulation
CMGC_CDK_CDK2_CDK3_ST	P06400	RB1	Q00526	CDK3	S780	R787*	787	Missense	distal	7	no	9.001	8.973	EPSD	GDSC	5.767	Down-regulation
CMGC_CDK_CDK2_CDK3_ST	P06400	RB1	Q00526	CDK3	S788	R787*	787	Missense	proximal	-1	no	7.305	7.296	EPSD	GDSC	5.767	Down-regulation
CMGC_CDK_CDK2_CDK3_ST	P06400	RB1	Q00526	CDK3	S795	G801*	801	Missense	distal	6	no	7.086	6.984	EPSD	GDSC	5.767	Down-regulation
CMGC_CDK_CDK2_CDK3_ST	P06400	RB1	Q00526	CDK3	S807	G801*	801	Missense	distal	-6	no	13.237	12.862	PhosphoSitePlus;EPSD	GDSC	5.767	Down-regulation
CMGC_CDK_CDK2_CDK3_ST	P06400	RB1	Q00526	CDK3	T821	L819V	819	Missense	proximal	-2	no	6.209	5.985	EPSD	GDSC;CCLE	5.767	Down-regulation
CMGC_CDK_CDK2_CDK3_ST	P06400	RB1	Q00526	CDK3	T826	L819V	819	Missense	distal	-7	no	8.468	8.182	EPSD	GDSC;CCLE	5.767	Down-regulation
Other_WNK_WNK2_ST	Q9UEW8	STK39	Q9Y3S1	WNK2	T224	G221S	221	Missense	distal	-3	no	2.550	2.253	EPSD	GDSC	2.413	Loss
Other_WNK_WNK2_ST	Q9UEW8	STK39	Q9Y3S1	WNK2	S401	Q402R	402	Missense	proximal	1	no	2.221	2.470	EPSD	GDSC;CCLE	2.413	Gain
Other_WNK_WNK2_ST	Q9H4A3	WNK1	Q9Y3S1	WNK2	S2012	H2006Y	2006	Missense	distal	-6	no	2.350	2.472	EPSD	GDSC;CCLE	2.413	Gain
AGC_RSK_MSK_RPS6KA4_ST	P54253	ATXN1	O75676	RPS6KA4	S25	T32S	32	Missense	distal	7	no	2.589	2.798	EPSD	GDSC	2.457	Up-regulation
AGC_RSK_MSK_RPS6KA4_ST	P54253	ATXN1	O75676	RPS6KA4	S25	I19T	19	Missense	distal	-6	no	2.589	2.590	EPSD	GDSC	2.457	Up-regulation
AGC_RSK_MSK_RPS6KA4_ST	P54253	ATXN1	O75676	RPS6KA4	S26	T32S	32	Missense	distal	6	no	3.629	3.618	EPSD	GDSC	2.457	Down-regulation
AGC_RSK_MSK_RPS6KA4_ST	P54253	ATXN1	O75676	RPS6KA4	S26	I19T	19	Missense	distal	-7	no	3.629	3.698	EPSD	GDSC	2.457	Up-regulation
AGC_RSK_MSK_RPS6KA4_ST	P54253	ATXN1	O75676	RPS6KA4	S775	E778Q	778	Missense	distal	3	no	4.941	4.214	PhosphoSitePlus	GDSC;CCLE	2.457	Down-regulation
AGC_RSK_MSK_RPS6KA4_ST	Q04206	RELA	O75676	RPS6KA4	S203	V199A	199	Missense	distal	-4	no	3.044	3.045	EPSD	GDSC;CCLE	2.457	Up-regulation
AGC_RSK_MSK_RPS6KA4_ST	Q04206	RELA	O75676	RPS6KA4	S238	D243Y	243	Missense	distal	5	no	2.423	2.476	EPSD	GDSC;CCLE	2.457	Gain
AGC_RSK_MSK_RPS6KA4_ST	Q04206	RELA	O75676	RPS6KA4	S261	D259G	259	Missense	proximal	-2	no	2.924	2.926	EPSD	GDSC;CCLE	2.457	Up-regulation
AGC_RSK_MSK_RPS6KA4_ST	Q04206	RELA	O75676	RPS6KA4	S261	A258T	258	Missense	distal	-3	no	2.924	3.231	EPSD	GDSC;CCLE	2.457	Up-regulation
AGC_RSK_MSK_RPS6KA4_ST	O75676	RPS6KA4	O75676	RPS6KA4	T178	L177F	177	Missense	proximal	-1	no	3.288	3.289	EPSD	GDSC;CCLE	2.457	Up-regulation
AGC_RSK_MSK_RPS6KA4_ST	O75676	RPS6KA4	O75676	RPS6KA4	S634	G637E	637	Missense	distal	3	no	4.360	4.417	EPSD	GDSC;CCLE	2.457	Up-regulation
AGC_RSK_MSK_RPS6KA4_ST	O75676	RPS6KA4	O75676	RPS6KA4	S745	S741Y	741	Missense	distal	-4	no	3.872	3.873	EPSD	GDSC;CCLE	2.457	Up-regulation
AGC_RSK_MSK_RPS6KA4_ST	O75676	RPS6KA4	O75676	RPS6KA4	S745	R742C	742	Missense	distal	-3	no	3.872	2.466	EPSD	GDSC;CCLE	2.457	Down-regulation
AGC_RSK_MSK_RPS6KA4_ST	O75676	RPS6KA4	O75676	RPS6KA4	S745	T739P	739	Missense	distal	-6	no	3.872	3.871	EPSD	GDSC;CCLE	2.457	Down-regulation
TKL_MLK_ILK_ILK_ST	O14950	MYL12B	Q13418	ILK	T19	R14H	14	Missense	distal	-5	no	21.935	21.823	EPSD;PhosphoSitePlus	GDSC;CCLE	15.108	Down-regulation
TKL_MLK_ILK_ILK_ST	O14950	MYL12B	Q13418	ILK	T19	Q16*	16	Missense	distal	-3	no	21.935	24.453	EPSD;PhosphoSitePlus	GDSC	15.108	Up-regulation
TKL_MLK_ILK_ILK_ST	O14950	MYL12B	Q13418	ILK	S20	R14H	14	Missense	distal	-6	no	20.941	21.085	PhosphoSitePlus;EPSD	GDSC;CCLE	15.108	Up-regulation
TKL_MLK_ILK_ILK_ST	O14950	MYL12B	Q13418	ILK	S20	Q16*	16	Missense	distal	-4	no	20.941	19.781	PhosphoSitePlus;EPSD	GDSC	15.108	Down-regulation
TKL_MLK_ILK_ILK_ST	P31749	AKT1	Q13418	ILK	T65	Q59*	59	Missense	distal	-6	no	15.698	15.014	EPSD	GDSC	15.108	Loss
TKL_MLK_ILK_ILK_ST	Q96C90	PPP1R14B	Q13418	ILK	T57	Q53E	53	Missense	distal	-4	no	41.632	42.303	PhosphoSitePlus	GDSC;CCLE	15.108	Up-regulation
TKL_LISK_TESK_TESK1_ST	P23528	CFL1	Q15569	TESK1	S3	G4D	4	Missense	proximal	1	no	9.660	9.668	PhosphoSitePlus	GDSC	1.889	Up-regulation
CK1_VRK_VRK1_ST	P38432	COIL	Q99986	VRK1	S316	S316N	316	Missense	central	0	yes	0.297	0.000	EPSD	GDSC	0.296	Loss
CK1_VRK_VRK1_ST	P38432	COIL	Q99986	VRK1	S317	S316N	316	Missense	proximal	-1	no	0.331	0.335	EPSD	GDSC	0.296	Up-regulation
CK1_VRK_VRK1_ST	P38432	COIL	Q99986	VRK1	S486	T485S	485	Missense	proximal	-1	no	0.327	0.326	EPSD	GDSC;CCLE	0.296	Down-regulation
CK1_VRK_VRK1_ST	P38432	COIL	Q99986	VRK1	S487	T485S	485	Missense	proximal	-2	no	0.339	0.323	EPSD	GDSC;CCLE	0.296	Down-regulation
CK1_VRK_VRK1_ST	P05412	JUN	Q99986	VRK1	S29	S23N	23	Missense	distal	-6	no	0.210	0.310	EPSD	GDSC;CCLE	0.296	Gain
CK1_VRK_VRK1_ST	P15336	ATF2	Q99986	VRK1	S62	V63A	63	Missense	proximal	1	no	0.560	0.557	PhosphoSitePlus;EPSD	GDSC;CCLE	0.296	Down-regulation
CK1_VRK_VRK1_ST	P15336	ATF2	Q99986	VRK1	S136	Q134H	134	Missense	proximal	-2	no	0.374	0.369	EPSD	GDSC;CCLE	0.296	Down-regulation
CK1_VRK_VRK1_ST	P04637	TP53	Q99986	VRK1	S106	Q100*	100	Missense	distal	-6	no	0.206	0.312	EPSD	GDSC	0.296	Gain
CK1_VRK_VRK1_ST	P04637	TP53	Q99986	VRK1	S149	Q144*	144	Missense	distal	-5	no	0.377	0.322	EPSD	GDSC	0.296	Down-regulation
CK1_VRK_VRK1_ST	P04637	TP53	Q99986	VRK1	S215	R209*	209	Missense	distal	-6	no	0.198	0.333	EPSD	GDSC	0.296	Gain
CK1_VRK_VRK1_ST	P04637	TP53	Q99986	VRK1	T312	R306*	306	Missense	distal	-6	no	0.174	0.309	EPSD	GDSC	0.296	Gain
AGC_PKC_PKCi_PRKCI_ST	Q4VCS5	AMOT	P41743	PRKCI	T750	L751I	751	Missense	proximal	1	no	9.318	8.493	EPSD;PhosphoSitePlus	GDSC	6.376	Down-regulation
AGC_PKC_PKCi_PRKCI_ST	P08151	GLI1	P41743	PRKCI	S86	P87S	87	Missense	proximal	1	no	8.494	5.445	EPSD	GDSC;CCLE	6.376	Loss
AGC_PKC_PKCi_PRKCI_ST	P08151	GLI1	P41743	PRKCI	S92	P87S	87	Missense	distal	-5	no	5.874	7.063	EPSD	GDSC;CCLE	6.376	Gain
AGC_PKC_PKCi_PRKCI_ST	P08151	GLI1	P41743	PRKCI	S937	V936I	936	Missense	proximal	-1	no	6.947	6.992	EPSD	GDSC;CCLE	6.376	Up-regulation
AGC_PKC_PKCi_PRKCI_ST	P10636	MAPT	P41743	PRKCI	T71	P78T	78	Missense	distal	7	no	7.912	8.016	EPSD	GDSC;CCLE	6.376	Up-regulation
AGC_PKC_PKCi_PRKCI_ST	P10636	MAPT	P41743	PRKCI	T123	E125G	125	Missense	proximal	2	no	8.172	6.972	EPSD	GDSC	6.376	Down-regulation
AGC_PKC_PKCi_PRKCI_ST	P10636	MAPT	P41743	PRKCI	S214	V218G	218	Missense	distal	4	no	10.639	10.538	EPSD	GDSC	6.376	Down-regulation
AGC_PKC_PKCi_PRKCI_ST	P10636	MAPT	P41743	PRKCI	S341	P340L	340	Missense	proximal	-1	no	6.535	6.492	EPSD	GDSC;CCLE	6.376	Down-regulation
AGC_PKC_PKCi_PRKCI_ST	P10636	MAPT	P41743	PRKCI	S341	G339S	339	Missense	proximal	-2	no	6.535	6.686	EPSD	GDSC;CCLE	6.376	Up-regulation
AGC_PKC_PKCi_PRKCI_ST	P10636	MAPT	P41743	PRKCI	T470	A475V	475	Missense	distal	5	no	9.903	9.631	EPSD	GDSC;CCLE	6.376	Down-regulation
AGC_PKC_PKCi_PRKCI_ST	P10636	MAPT	P41743	PRKCI	S641	V635I	635	Missense	distal	-6	no	10.820	10.926	EPSD	GDSC	6.376	Up-regulation
AGC_PKC_PKCi_PRKCI_ST	P10636	MAPT	P41743	PRKCI	S739	S739C	739	Missense	central	0	yes	6.466	0.000	EPSD	GDSC	6.376	Loss
AGC_PKC_PKCi_PRKCI_ST	Q13464	ROCK1	P41743	PRKCI	T887	L881I	881	Missense	distal	-6	no	8.702	8.636	EPSD	GDSC;CCLE	6.376	Down-regulation
AGC_PKC_PKCi_PRKCI_ST	Q13464	ROCK1	P41743	PRKCI	T1331	R1326H	1326	Missense	distal	-5	no	6.613	4.684	EPSD	GDSC	6.376	Loss
AGC_PKC_PKCi_PRKCI_ST	Q13464	ROCK1	P41743	PRKCI	S1333	R1326H	1326	Missense	distal	-7	no	6.478	7.011	EPSD;PhosphoSitePlus	GDSC	6.376	Up-regulation
AGC_PKC_PKCi_PRKCI_ST	Q92934	BAD	P41743	PRKCI	S25	D29N	29	Missense	distal	4	no	8.959	8.898	EPSD	GDSC	6.376	Down-regulation
AGC_PKC_PKCi_PRKCI_ST	Q13118	KLF10	P41743	PRKCI	T422	F429C	429	Missense	distal	7	no	8.101	8.025	EPSD	GDSC;CCLE	6.376	Down-regulation
AGC_PKC_PKCi_PRKCI_ST	Q13118	KLF10	P41743	PRKCI	T445	H443Q	443	Missense	proximal	-2	no	9.688	9.617	EPSD;PhosphoSitePlus	GDSC	6.376	Down-regulation
AGC_PKC_PKCi_PRKCI_ST	P15311	EZR	P41743	PRKCI	T299	R293H	293	Missense	distal	-6	no	6.868	7.248	EPSD	GDSC;CCLE	6.376	Up-regulation
AGC_PKC_PKCi_PRKCI_ST	P08047	SP1	P41743	PRKCI	S59	A66G	66	Missense	distal	7	no	12.403	12.338	PhosphoSitePlus	GDSC;CCLE	6.376	Down-regulation
AGC_PKC_PKCi_PRKCI_ST	Q14247	CTTN	P41743	PRKCI	S109	E103K	103	Missense	distal	-6	no	7.813	7.468	EPSD	GDSC;CCLE	6.376	Down-regulation
AGC_PKC_PKCi_PRKCI_ST	Q14247	CTTN	P41743	PRKCI	S109	V115A	115	Missense	distal	6	no	7.813	8.010	EPSD	GDSC;CCLE	6.376	Up-regulation
AGC_PKC_PKCi_PRKCI_ST	Q14247	CTTN	P41743	PRKCI	S113	V115A	115	Missense	proximal	2	no	6.589	7.636	EPSD	GDSC;CCLE	6.376	Up-regulation
AGC_PKC_PKCi_PRKCI_ST	P49757	NUMB	P41743	PRKCI	S7	R10K	10	Missense	distal	3	no	11.823	11.974	EPSD;PhosphoSitePlus	GDSC;CCLE	6.376	Up-regulation
AGC_PKC_PKCi_PRKCI_ST	P49757	NUMB	P41743	PRKCI	S276	F280L	280	Missense	distal	4	no	8.385	8.675	EPSD;PhosphoSitePlus	GDSC;CCLE	6.376	Up-regulation
AGC_PKC_PKCi_PRKCI_ST	P49757	NUMB	P41743	PRKCI	S627	A622V	622	Missense	distal	-5	no	12.310	10.830	EPSD	GDSC	6.376	Down-regulation
AGC_PKC_PKCi_PRKCI_ST	P49757	NUMB	P41743	PRKCI	S627	T631S	631	Missense	distal	4	no	12.310	12.250	EPSD	GDSC	6.376	Down-regulation
AGC_PKC_PKCi_PRKCI_ST	P49757	NUMB	P41743	PRKCI	S634	S640F	640	Missense	distal	6	no	7.373	7.246	EPSD	GDSC;CCLE	6.376	Down-regulation
AGC_PKC_PKCi_PRKCI_ST	P49757	NUMB	P41743	PRKCI	S634	T631S	631	Missense	distal	-3	no	7.373	7.566	EPSD	GDSC	6.376	Up-regulation
AGC_PKC_PKCi_PRKCI_ST	Q9UBS0	RPS6KB2	P41743	PRKCI	S266	D261E	261	Missense	distal	-5	no	6.223	8.260	EPSD	GDSC;CCLE	6.376	Gain
AGC_PKC_PKCi_PRKCI_ST	Q9UBS0	RPS6KB2	P41743	PRKCI	S379	A375S	375	Missense	distal	-4	no	6.505	6.504	EPSD	GDSC;CCLE	6.376	Down-regulation
AGC_PKC_PKCi_PRKCI_ST	Q9UBS0	RPS6KB2	P41743	PRKCI	S379	D372H	372	Missense	distal	-7	no	6.505	5.967	EPSD	GDSC;CCLE	6.376	Loss
AGC_PKC_PKCi_PRKCI_ST	Q9UBS0	RPS6KB2	P41743	PRKCI	S417	R419Q	419	Missense	proximal	2	no	7.655	7.007	EPSD	GDSC;CCLE	6.376	Down-regulation
AGC_PKC_PKCi_PRKCI_ST	Q9UBS0	RPS6KB2	P41743	PRKCI	T470	R465C	465	Missense	distal	-5	no	8.210	3.180	EPSD	GDSC;CCLE	6.376	Loss
AGC_PKC_PKCi_PRKCI_ST	P27448	MARK3	P41743	PRKCI	S400	S396I	396	Missense	distal	-4	no	6.466	6.134	EPSD	GDSC;CCLE	6.376	Loss
AGC_PKC_PKCi_PRKCI_ST	P27448	MARK3	P41743	PRKCI	T576	P581L	581	Missense	distal	5	no	7.161	7.228	EPSD	GDSC;CCLE	6.376	Up-regulation
AGC_PKC_PKCi_PRKCI_ST	P27448	MARK3	P41743	PRKCI	T576	G579A	579	Missense	distal	3	no	7.161	6.765	EPSD	GDSC	6.376	Down-regulation
AGC_PKC_PKCi_PRKCI_ST	P27448	MARK3	P41743	PRKCI	T576	R572W	572	Missense	distal	-4	no	7.161	6.777	EPSD	GDSC;CCLE	6.376	Down-regulation
AGC_PKC_PKCi_PRKCI_ST	P27448	MARK3	P41743	PRKCI	S618	I622M	622	Missense	distal	4	no	12.221	11.874	EPSD	GDSC;CCLE	6.376	Down-regulation
AGC_PKC_PKCi_PRKCI_ST	P27448	MARK3	P41743	PRKCI	S734	A739G	739	Missense	distal	5	no	8.630	8.430	EPSD	GDSC;CCLE	6.376	Down-regulation
AGC_PKC_PKCi_PRKCI_ST	Q969H0	FBXW7	P41743	PRKCI	S10	R13*	13	Missense	distal	3	no	9.953	10.589	PhosphoSitePlus;EPSD	GDSC	6.376	Up-regulation
AGC_PKC_PKCi_PRKCI_ST	Q969H0	FBXW7	P41743	PRKCI	S10	K11Q	11	Missense	proximal	1	no	9.953	8.563	PhosphoSitePlus;EPSD	GDSC;CCLE	6.376	Down-regulation
AGC_PKC_PKCi_PRKCI_ST	Q969H0	FBXW7	P41743	PRKCI	S18	R13*	13	Missense	distal	-5	no	9.121	6.066	EPSD;PhosphoSitePlus	GDSC	6.376	Loss
AGC_PKC_PKCi_PRKCI_ST	Q969H0	FBXW7	P41743	PRKCI	S18	K11Q	11	Missense	distal	-7	no	9.121	8.790	EPSD;PhosphoSitePlus	GDSC;CCLE	6.376	Down-regulation
AGC_PKC_PKCi_PRKCI_ST	Q969H0	FBXW7	P41743	PRKCI	T680	W673*	673	Missense	distal	-7	no	7.320	7.153	EPSD	GDSC	6.376	Down-regulation
AGC_PKC_PKCi_PRKCI_ST	Q8TEW0	PARD3	P41743	PRKCI	T453	G457S	457	Missense	distal	4	no	9.219	8.874	EPSD	GDSC;CCLE	6.376	Down-regulation
AGC_PKC_PKCi_PRKCI_ST	Q8TEW0	PARD3	P41743	PRKCI	T453	N452D	452	Missense	proximal	-1	no	9.219	9.236	EPSD	GDSC	6.376	Up-regulation
AGC_PKC_PKCi_PRKCI_ST	Q8TEW0	PARD3	P41743	PRKCI	T468	I462V	462	Missense	distal	-6	no	7.257	7.151	EPSD	GDSC;CCLE	6.376	Down-regulation
AGC_PKC_PKCi_PRKCI_ST	Q8TEW0	PARD3	P41743	PRKCI	S523	V520L	520	Missense	distal	-3	no	7.727	8.495	EPSD	GDSC;CCLE	6.376	Up-regulation
AGC_PKC_PKCi_PRKCI_ST	Q8TEW0	PARD3	P41743	PRKCI	T661	T661I	661	Missense	central	0	yes	7.614	0.000	EPSD	GDSC;CCLE	6.376	Loss
AGC_PKC_PKCi_PRKCI_ST	Q8TEW0	PARD3	P41743	PRKCI	T668	T661I	661	Missense	distal	-7	no	8.256	8.827	EPSD	GDSC;CCLE	6.376	Up-regulation
AGC_PKC_PKCi_PRKCI_ST	Q8TEW0	PARD3	P41743	PRKCI	T901	E899K	899	Missense	proximal	-2	no	7.048	7.118	EPSD	GDSC;CCLE	6.376	Up-regulation
AGC_PKC_PKCi_PRKCI_ST	Q8TEW0	PARD3	P41743	PRKCI	S1116	G1120R	1120	Missense	distal	4	no	8.175	7.519	EPSD	GDSC;CCLE	6.376	Down-regulation
AGC_PKC_PKCi_PRKCI_ST	Q8TEW0	PARD3	P41743	PRKCI	S1178	D1172Y	1172	Missense	distal	-6	no	11.586	11.358	EPSD	GDSC;CCLE	6.376	Down-regulation
AGC_PKC_PKCi_PRKCI_ST	Q8TEW0	PARD3	P41743	PRKCI	S1261	S1265P	1265	Missense	distal	4	no	8.207	8.269	EPSD	GDSC;CCLE	6.376	Up-regulation
AGC_PKC_PKCi_PRKCI_ST	Q8TEW0	PARD3	P41743	PRKCI	S1261	Q1263K	1263	Missense	proximal	2	no	8.207	7.988	EPSD	GDSC;CCLE	6.376	Down-regulation
AGC_PKC_PKCi_PRKCI_ST	P78545	ELF3	P41743	PRKCI	S68	T70M	70	Missense	proximal	2	no	9.480	8.906	PhosphoSitePlus	GDSC	6.376	Down-regulation
AGC_PKC_PKCi_PRKCI_ST	P78545	ELF3	P41743	PRKCI	S254	R247*	247	Missense	distal	-7	no	8.404	9.589	EPSD	GDSC	6.376	Up-regulation
TK_Syk_ZAP70_Y	O43561	LAT	P43403	ZAP70	Y220	L214R	214	Missense	distal	-6	no	9.882	9.489	EPSD	GDSC	5.220	Down-regulation
TK_Syk_ZAP70_Y	O43561	LAT	P43403	ZAP70	Y220	E226Q	226	Missense	distal	6	no	9.882	9.649	EPSD	GDSC;CCLE	5.220	Down-regulation
TK_Syk_ZAP70_Y	P29353	SHC1	P43403	ZAP70	Y349	Y349H	349	Missense	central	0	yes	11.718	0.000	EPSD	GDSC;CCLE	5.220	Loss
TK_Syk_ZAP70_Y	P29353	SHC1	P43403	ZAP70	Y350	Y349H	349	Missense	proximal	-1	no	9.502	9.390	EPSD	GDSC;CCLE	5.220	Down-regulation
TK_Syk_ZAP70_Y	Q9UQC2	GAB2	P43403	ZAP70	Y194	Y194C	194	Missense	central	0	yes	6.412	0.000	EPSD	GDSC;CCLE	5.220	Loss
TK_Syk_ZAP70_Y	Q9UQC2	GAB2	P43403	ZAP70	Y266	S264G	264	Missense	proximal	-2	no	9.840	9.133	EPSD	GDSC	5.220	Down-regulation
TK_Syk_ZAP70_Y	Q9UQC2	GAB2	P43403	ZAP70	Y293	T294I	294	Missense	proximal	1	no	7.692	6.723	EPSD	GDSC;CCLE	5.220	Down-regulation
TK_Syk_ZAP70_Y	Q9UQC2	GAB2	P43403	ZAP70	Y293	E286K	286	Missense	distal	-7	no	7.692	5.978	EPSD	GDSC;CCLE	5.220	Down-regulation
TK_Syk_ZAP70_Y	Q9UQC2	GAB2	P43403	ZAP70	Y293	T294P	294	Missense	proximal	1	no	7.692	6.332	EPSD	GDSC;CCLE	5.220	Down-regulation
TK_Syk_ZAP70_Y	Q9UQC2	GAB2	P43403	ZAP70	Y614	V612A	612	Missense	proximal	-2	no	9.402	10.418	PhosphoSitePlus	GDSC;CCLE	5.220	Up-regulation
TK_Syk_ZAP70_Y	P43403	ZAP70	P43403	ZAP70	Y292	G291E	291	Missense	proximal	-1	no	12.294	12.734	EPSD;PhosphoSitePlus	GDSC;CCLE	5.220	Up-regulation
TK_Syk_ZAP70_Y	P43403	ZAP70	P43403	ZAP70	Y357	R358C	358	Missense	proximal	1	no	4.801	5.298	EPSD	GDSC;CCLE	5.220	Gain
TK_Syk_ZAP70_Y	P43403	ZAP70	P43403	ZAP70	Y492	Y492H	492	Missense	central	0	yes	8.864	0.000	EPSD;PhosphoSitePlus	GDSC;CCLE	5.220	Loss
TK_Syk_ZAP70_Y	P43403	ZAP70	P43403	ZAP70	Y493	Y492H	492	Missense	proximal	-1	no	9.310	9.199	EPSD;PhosphoSitePlus	GDSC;CCLE	5.220	Down-regulation
TK_Syk_ZAP70_Y	P43403	ZAP70	P43403	ZAP70	Y569	C575F	575	Missense	distal	6	no	6.328	6.194	EPSD	GDSC;CCLE	5.220	Down-regulation
TK_Syk_ZAP70_Y	Q13094	LCP2	P43403	ZAP70	Y113	S107Y	107	Missense	distal	-6	no	13.540	12.619	EPSD;PhosphoSitePlus	GDSC;CCLE	5.220	Down-regulation
TK_Syk_ZAP70_Y	Q13094	LCP2	P43403	ZAP70	Y128	G126E	126	Missense	proximal	-2	no	12.246	12.842	EPSD;PhosphoSitePlus	GDSC	5.220	Up-regulation
Atypical_BCR_BCR_ST	P27348	YWHAQ	P11274	BCR	S232	L227V	227	Missense	distal	-5	no	17.130	16.829	PhosphoSitePlus	GDSC	1.927	Down-regulation
Atypical_BCR_BCR_ST	P63104	YWHAZ	P11274	BCR	S156	P162S	162	Missense	distal	6	no	3.782	3.785	EPSD	GDSC;CCLE	1.927	Up-regulation
Other_NEK_NEK6_NEK7_ST	Q15058	KIF14	Q8TDX7	NEK7	S56	D51N	51	Missense	distal	-5	no	8.347	8.301	PhosphoSitePlus;EPSD	GDSC	3.120	Down-regulation
Other_NEK_NEK6_NEK7_ST	Q15058	KIF14	Q8TDX7	NEK7	T66	S70Y	70	Missense	distal	4	no	3.221	3.346	EPSD	GDSC;CCLE	3.120	Up-regulation
Other_NEK_NEK6_NEK7_ST	Q15058	KIF14	Q8TDX7	NEK7	T81	L80V	80	Missense	proximal	-1	no	3.616	3.623	EPSD	GDSC;CCLE	3.120	Up-regulation
Other_NEK_NEK6_NEK7_ST	Q15058	KIF14	Q8TDX7	NEK7	S201	E198*	198	Missense	distal	-3	no	3.957	4.248	EPSD	GDSC	3.120	Up-regulation
Other_NEK_NEK6_NEK7_ST	Q15058	KIF14	Q8TDX7	NEK7	S607	H614Y	614	Missense	distal	7	no	7.160	6.972	EPSD;PhosphoSitePlus	GDSC;CCLE	3.120	Down-regulation
Other_NEK_NEK6_NEK7_ST	Q15058	KIF14	Q8TDX7	NEK7	S641	S648C	648	Missense	distal	7	no	2.858	3.180	EPSD	GDSC;CCLE	3.120	Gain
Other_NEK_NEK6_NEK7_ST	Q15058	KIF14	Q8TDX7	NEK7	S1466	E1468*	1468	Missense	proximal	2	no	3.633	3.614	EPSD	GDSC	3.120	Down-regulation
Other_NEK_NEK6_NEK7_ST	Q15058	KIF14	Q8TDX7	NEK7	S1466	M1461V	1461	Missense	distal	-5	no	3.633	3.609	EPSD	GDSC;CCLE	3.120	Down-regulation
Other_NEK_NEK6_NEK7_ST	Q15058	KIF14	Q8TDX7	NEK7	S1466	A1472T	1472	Missense	distal	6	no	3.633	3.528	EPSD	GDSC;CCLE	3.120	Down-regulation
Other_NEK_NEK6_NEK7_ST	P52732	KIF11	Q8TDX7	NEK7	T294	T300S	300	Missense	distal	6	no	5.252	5.198	EPSD	GDSC;CCLE	3.120	Down-regulation
Other_NEK_NEK6_NEK7_ST	P52732	KIF11	Q8TDX7	NEK7	T463	N456S	456	Missense	distal	-7	no	3.451	1.629	EPSD	GDSC;CCLE	3.120	Loss
CMGC_DYRK_DYRK2_DYRK3_ST	Q96B36	AKT1S1	O43781	DYRK3	T97	R95W	95	Missense	proximal	-2	no	2.413	2.005	EPSD	GDSC;CCLE	1.682	Down-regulation
CMGC_DYRK_DYRK2_DYRK3_ST	Q96B36	AKT1S1	O43781	DYRK3	S187	P185S	185	Missense	proximal	-2	no	2.735	1.598	EPSD	GDSC;CCLE	1.682	Loss
CMGC_DYRK_DYRK2_DYRK3_ST	Q96B36	AKT1S1	O43781	DYRK3	S187	V190I	190	Missense	distal	3	no	2.735	2.714	EPSD	GDSC	1.682	Down-regulation
TK_Tec_TXK_Y	P42681	TXK	P42681	TXK	Y91	L90R	90	Missense	proximal	-1	no	5.928	5.945	EPSD;PhosphoSitePlus	GDSC;CCLE	1.475	Up-regulation
TKL_STKR_STKR1_BMPR1B_ST	Q15796	SMAD2	O00238	BMPR1B	S458	S464*	464	Missense	distal	6	no	-2.250	1.172	EPSD	GDSC	-1.120	Gain
TKL_STKR_STKR1_BMPR1B_ST	Q15796	SMAD2	O00238	BMPR1B	S460	S464*	464	Missense	distal	4	no	-2.469	0.953	EPSD	GDSC	-1.120	Gain
TKL_STKR_STKR1_BMPR1B_ST	Q15796	SMAD2	O00238	BMPR1B	S464	S464*	464	Missense	central	0	yes	-0.891	0.000	EPSD;PhosphoSitePlus	GDSC	-1.120	Loss
TKL_STKR_STKR1_BMPR1B_ST	Q15796	SMAD2	O00238	BMPR1B	S465	S464*	464	Missense	proximal	-1	no	-0.817	-0.891	PhosphoSitePlus;EPSD	GDSC	-1.120	Down-regulation
TKL_STKR_STKR1_BMPR1B_ST	Q15796	SMAD2	O00238	BMPR1B	S467	S464*	464	Missense	distal	-3	no	-0.834	-0.822	EPSD;PhosphoSitePlus	GDSC	-1.120	Up-regulation
TK_Jak_TYK2_Y	P17181	IFNAR1	P29597	TYK2	Y466	N465Y	465	Missense	proximal	-1	no	38.990	35.316	EPSD;PhosphoSitePlus	GDSC	21.015	Down-regulation
TK_Jak_TYK2_Y	O15304	SIVA1	P29597	TYK2	Y53	A50D	50	Missense	distal	-3	no	41.028	40.761	EPSD;PhosphoSitePlus	GDSC;CCLE	21.015	Down-regulation
TK_Fak_PTK2B_Y	Q14247	CTTN	Q14289	PTK2B	Y486	E490K	490	Missense	distal	4	no	663.322	649.026	PhosphoSitePlus;EPSD	GDSC;CCLE	366.093	Down-regulation
TK_Fak_PTK2B_Y	O43561	LAT	Q14289	PTK2B	Y220	L214R	214	Missense	distal	-6	no	496.553	494.689	EPSD	GDSC	366.093	Down-regulation
TK_Fak_PTK2B_Y	O43561	LAT	Q14289	PTK2B	Y220	E226Q	226	Missense	distal	6	no	496.553	496.517	EPSD	GDSC;CCLE	366.093	Down-regulation
TK_Fak_PTK2B_Y	P37840	SNCA	Q14289	PTK2B	Y125	M127I	127	Missense	proximal	2	no	505.058	504.603	PhosphoSitePlus	GDSC	366.093	Down-regulation
TK_Fak_PTK2B_Y	P37840	SNCA	Q14289	PTK2B	Y125	E130G	130	Missense	distal	5	no	505.058	451.818	PhosphoSitePlus	GDSC	366.093	Down-regulation
TK_Fak_PTK2B_Y	P37840	SNCA	Q14289	PTK2B	Y133	M127I	127	Missense	distal	-6	no	429.398	428.377	EPSD	GDSC	366.093	Down-regulation
TK_Fak_PTK2B_Y	P37840	SNCA	Q14289	PTK2B	Y133	E130G	130	Missense	distal	-3	no	429.398	328.767	EPSD	GDSC	366.093	Loss
TK_Fak_PTK2B_Y	Q14289	PTK2B	Q14289	PTK2B	Y402	C395Y	395	Missense	distal	-7	no	715.215	715.208	PhosphoSitePlus	GDSC;CCLE	366.093	Down-regulation
TK_Fak_PTK2B_Y	Q14289	PTK2B	Q14289	PTK2B	Y402	A403T	403	Missense	proximal	1	no	715.215	722.011	PhosphoSitePlus	GDSC;CCLE	366.093	Up-regulation
TK_Fak_PTK2B_Y	Q14289	PTK2B	Q14289	PTK2B	Y402	T409P	409	Missense	distal	7	no	715.215	712.110	PhosphoSitePlus	GDSC	366.093	Down-regulation
TK_Fak_PTK2B_Y	Q14289	PTK2B	Q14289	PTK2B	Y722	R719*	719	Missense	distal	-3	no	441.541	348.994	EPSD	GDSC	366.093	Loss
TK_Fak_PTK2B_Y	Q14289	PTK2B	Q14289	PTK2B	Y722	P724S	724	Missense	proximal	2	no	441.541	444.157	EPSD	GDSC;CCLE	366.093	Up-regulation
TK_Fak_PTK2B_Y	Q05397	PTK2	Q14289	PTK2B	Y407	T406I	406	Missense	proximal	-1	no	679.931	672.362	PhosphoSitePlus	GDSC;CCLE	366.093	Down-regulation
TK_Fak_PTK2B_Y	Q05397	PTK2	Q14289	PTK2B	Y407	P410H	410	Missense	distal	3	no	679.931	668.198	PhosphoSitePlus	GDSC;CCLE	366.093	Down-regulation
TK_Fak_PTK2B_Y	Q13586	STIM1	Q14289	PTK2B	Y130	V134M	134	Missense	distal	4	no	422.914	425.124	EPSD	GDSC;CCLE	366.093	Up-regulation
AGC_RSK_RSKp70_RPS6KB2_ST	Q15633	TARBP2	Q9UBS0	RPS6KB2	S283	C282Y	282	Missense	proximal	-1	no	10.205	9.593	PhosphoSitePlus	GDSC	4.103	Down-regulation
AGC_RSK_RSKp70_RPS6KB2_ST	Q15633	TARBP2	Q9UBS0	RPS6KB2	S283	S281R	281	Missense	proximal	-2	no	10.205	9.614	PhosphoSitePlus	GDSC	4.103	Down-regulation
AGC_RSK_RSKp70_RPS6KB2_ST	P49841	GSK3B	Q9UBS0	RPS6KB2	T7	T8P	8	Missense	proximal	1	no	4.056	4.339	EPSD	GDSC	4.103	Gain
AGC_RSK_RSKp70_RPS6KB2_ST	P49841	GSK3B	Q9UBS0	RPS6KB2	S9	T8P	8	Missense	proximal	-1	no	9.449	8.372	PhosphoSitePlus	GDSC	4.103	Down-regulation
AGC_RSK_RSKp70_RPS6KB2_ST	P05783	KRT18	Q9UBS0	RPS6KB2	S127	H128L	128	Missense	proximal	1	no	6.467	6.382	EPSD	GDSC	4.103	Down-regulation
AGC_RSK_RSKp70_RPS6KB2_ST	O00418	EEF2K	Q9UBS0	RPS6KB2	S71	Y69H	69	Missense	proximal	-2	no	5.698	5.673	EPSD	GDSC;CCLE	4.103	Down-regulation
AGC_RSK_RSKp70_RPS6KB2_ST	O00418	EEF2K	Q9UBS0	RPS6KB2	S243	R247C	247	Missense	distal	4	no	4.356	4.396	EPSD	GDSC	4.103	Up-regulation
AGC_RSK_RSKp70_RPS6KB2_ST	Q6R327	RICTOR	Q9UBS0	RPS6KB2	S35	R32L	32	Missense	distal	-3	no	5.932	-0.083	EPSD	GDSC;CCLE	4.103	Loss
AGC_RSK_RSKp70_RPS6KB2_ST	Q6R327	RICTOR	Q9UBS0	RPS6KB2	S1035	H1033Y	1033	Missense	proximal	-2	no	6.417	6.442	EPSD	GDSC	4.103	Up-regulation
AGC_RSK_RSKp70_RPS6KB2_ST	Q6R327	RICTOR	Q9UBS0	RPS6KB2	S1302	A1300T	1300	Missense	proximal	-2	no	5.813	6.298	EPSD	GDSC;CCLE	4.103	Up-regulation
AGC_RSK_RSKp70_RPS6KB2_ST	Q6R327	RICTOR	Q9UBS0	RPS6KB2	S1408	R1405*	1405	Missense	distal	-3	no	7.257	2.592	EPSD	GDSC	4.103	Loss
TK_Src_SrcA_FGR_Y	Q9UHD2	TBK1	P09769	FGR	Y340	H336Y	336	Missense	distal	-4	no	5.205	5.023	EPSD	GDSC;CCLE	5.114	Loss
TK_Src_SrcA_FGR_Y	Q9UHD2	TBK1	P09769	FGR	Y354	R357*	357	Missense	distal	3	no	9.835	9.637	PhosphoSitePlus;EPSD	GDSC	5.114	Down-regulation
TK_Src_SrcA_FGR_Y	Q9UHD2	TBK1	P09769	FGR	Y354	R358C	358	Missense	distal	4	no	9.835	9.220	PhosphoSitePlus;EPSD	GDSC;CCLE	5.114	Down-regulation
TK_Src_SRM_PTK6_Y	Q13882	PTK6	Q13882	PTK6	Y61	A56G	56	Missense	distal	-5	no	29.459	31.345	EPSD	GDSC	13.984	Up-regulation
TK_Src_SRM_PTK6_Y	Q13882	PTK6	Q13882	PTK6	Y66	E69K	69	Missense	distal	3	no	35.898	26.156	EPSD	GDSC	13.984	Down-regulation
TK_Src_SRM_PTK6_Y	P35222	CTNNB1	Q13882	PTK6	Y64	T59N	59	Missense	distal	-5	no	27.456	26.127	EPSD;PhosphoSitePlus	GDSC	13.984	Down-regulation
TK_Src_SRM_PTK6_Y	P35222	CTNNB1	Q13882	PTK6	Y142	A135V	135	Missense	distal	-7	no	16.974	16.563	PhosphoSitePlus;EPSD	GDSC;CCLE	13.984	Down-regulation
TK_Src_SRM_PTK6_Y	P56945	BCAR1	Q13882	PTK6	Y165	A161T	161	Missense	distal	-4	no	27.242	26.888	EPSD;PhosphoSitePlus	GDSC	13.984	Down-regulation
TK_Src_SRM_PTK6_Y	P56945	BCAR1	Q13882	PTK6	Y262	S260G	260	Missense	proximal	-2	no	23.113	21.761	EPSD	GDSC;CCLE	13.984	Down-regulation
TK_Src_SRM_PTK6_Y	P56945	BCAR1	Q13882	PTK6	Y267	V274F	274	Missense	distal	7	no	16.796	16.508	EPSD	GDSC;CCLE	13.984	Down-regulation
TK_Src_SRM_PTK6_Y	P56945	BCAR1	Q13882	PTK6	Y267	S260G	260	Missense	distal	-7	no	16.796	15.614	EPSD	GDSC;CCLE	13.984	Down-regulation
TK_Src_SRM_PTK6_Y	P56945	BCAR1	Q13882	PTK6	Y410	S407N	407	Missense	distal	-3	no	16.970	15.962	EPSD	GDSC	13.984	Down-regulation
TK_Src_SRM_PTK6_Y	P51692	STAT5B	Q13882	PTK6	Y683	S690C	690	Missense	distal	7	no	18.711	20.361	EPSD	GDSC;CCLE	13.984	Up-regulation
TK_Src_SRM_PTK6_Y	P49023	PXN	Q13882	PTK6	Y181	S188R	188	Missense	distal	7	no	15.662	17.360	EPSD	GDSC	13.984	Up-regulation
TK_Src_SRM_PTK6_Y	Q13017	ARHGAP5	Q13882	PTK6	Y1091	P1087S	1087	Missense	distal	-4	no	23.828	24.268	EPSD	GDSC;CCLE	13.984	Up-regulation
TK_Src_SRM_PTK6_Y	Q13017	ARHGAP5	Q13882	PTK6	Y1091	I1095L	1095	Missense	distal	4	no	23.828	23.338	EPSD	GDSC;CCLE	13.984	Down-regulation
TK_Src_SRM_PTK6_Y	Q13017	ARHGAP5	Q13882	PTK6	Y1091	I1098V	1098	Missense	distal	7	no	23.828	23.710	EPSD	GDSC	13.984	Down-regulation
TK_Src_SRM_PTK6_Y	Q13017	ARHGAP5	Q13882	PTK6	Y1091	S1088L	1088	Missense	distal	-3	no	23.828	20.224	EPSD	GDSC;CCLE	13.984	Down-regulation
Other_ULK_ULK_ULK1_ST	Q8N122	RPTOR	O75385	ULK1	S738	S734N	734	Missense	distal	-4	no	43.563	44.023	EPSD	GDSC;CCLE	29.179	Up-regulation
Other_ULK_ULK_ULK1_ST	Q8N122	RPTOR	O75385	ULK1	S792	S798P	798	Missense	distal	6	no	40.283	39.811	EPSD;PhosphoSitePlus	GDSC	29.179	Down-regulation
Other_ULK_ULK_ULK1_ST	Q7Z3C6	ATG9A	O75385	ULK1	S14	S18T	18	Missense	distal	4	no	40.041	39.678	EPSD;PhosphoSitePlus	GDSC;CCLE	29.179	Down-regulation
Other_ULK_ULK_ULK1_ST	Q7Z3C6	ATG9A	O75385	ULK1	S761	A760V	760	Missense	proximal	-1	no	39.220	39.302	PhosphoSitePlus;EPSD	GDSC;CCLE	29.179	Up-regulation
Other_ULK_ULK_ULK1_ST	P08235	NR3C2	O75385	ULK1	S311	S314L	314	Missense	distal	3	no	31.527	34.737	EPSD	GDSC;CCLE	29.179	Up-regulation
Other_ULK_ULK_ULK1_ST	Q8TEV9	SMCR8	O75385	ULK1	S465	M462V	462	Missense	distal	-3	no	41.519	26.810	EPSD	GDSC;CCLE	29.179	Loss
Other_ULK_ULK_ULK1_ST	Q8TEV9	SMCR8	O75385	ULK1	S465	S468G	468	Missense	distal	3	no	41.519	42.869	EPSD	GDSC;CCLE	29.179	Up-regulation
Other_ULK_ULK_ULK1_ST	Q8TEV9	SMCR8	O75385	ULK1	S465	D461G	461	Missense	distal	-4	no	41.519	38.984	EPSD	GDSC;CCLE	29.179	Down-regulation
Other_ULK_ULK_ULK1_ST	Q15436	SEC23A	O75385	ULK1	S150	S156N	156	Missense	distal	6	no	32.746	32.612	EPSD	GDSC;CCLE	29.179	Down-regulation
Other_ULK_ULK_ULK1_ST	Q15436	SEC23A	O75385	ULK1	S207	T212A	212	Missense	distal	5	no	41.270	41.971	PhosphoSitePlus;EPSD	GDSC;CCLE	29.179	Up-regulation
Other_ULK_ULK_ULK1_ST	Q15436	SEC23A	O75385	ULK1	S567	F568V	568	Missense	proximal	1	no	30.917	30.925	EPSD	GDSC;CCLE	29.179	Up-regulation
Other_ULK_ULK_ULK1_ST	Q15436	SEC23A	O75385	ULK1	S640	L636F	636	Missense	distal	-4	no	36.566	32.909	EPSD	GDSC	29.179	Down-regulation
Other_ULK_ULK_ULK1_ST	O75143	ATG13	O75385	ULK1	S334	C331R	331	Missense	distal	-3	no	33.683	36.957	EPSD	GDSC;CCLE	29.179	Up-regulation
Other_ULK_ULK_ULK1_ST	P08237	PFKM	O75385	ULK1	S74	Q78*	78	Missense	distal	4	no	43.681	43.136	PhosphoSitePlus;EPSD	GDSC	29.179	Down-regulation
Other_ULK_ULK_ULK1_ST	P08237	PFKM	O75385	ULK1	S74	Q78H	78	Missense	distal	4	no	43.681	45.053	PhosphoSitePlus;EPSD	GDSC;CCLE	29.179	Up-regulation
Other_ULK_ULK_ULK1_ST	Q15437	SEC23B	O75385	ULK1	S150	A146V	146	Missense	distal	-4	no	31.701	29.473	EPSD	GDSC;CCLE	29.179	Down-regulation
Other_ULK_ULK_ULK1_ST	Q15437	SEC23B	O75385	ULK1	T407	F400L	400	Missense	distal	-7	no	34.319	34.860	EPSD	GDSC	29.179	Up-regulation
Other_ULK_ULK_ULK1_ST	Q14457	BECN1	O75385	ULK1	S15	Q13*	13	Missense	proximal	-2	no	44.157	37.733	EPSD;PhosphoSitePlus	GDSC	29.179	Down-regulation
Other_ULK_ULK_ULK1_ST	Q14457	BECN1	O75385	ULK1	S15	S10N	10	Missense	distal	-5	no	44.157	41.687	EPSD;PhosphoSitePlus	GDSC;CCLE	29.179	Down-regulation
Other_ULK_ULK_ULK1_ST	Q14457	BECN1	O75385	ULK1	S414	S421T	421	Missense	distal	7	no	29.833	30.420	EPSD	GDSC;CCLE	29.179	Up-regulation
Other_ULK_ULK_ULK1_ST	P06733	ENO1	O75385	ULK1	S115	V118I	118	Missense	distal	3	no	42.919	43.103	PhosphoSitePlus;EPSD	GDSC	29.179	Up-regulation
Other_ULK_ULK_ULK1_ST	P06733	ENO1	O75385	ULK1	S353	C357Y	357	Missense	distal	4	no	34.369	34.211	EPSD	GDSC;CCLE	29.179	Down-regulation
Other_ULK_ULK_ULK1_ST	Q8NFG4	FLCN	O75385	ULK1	S62	A67T	67	Missense	distal	5	no	32.991	32.290	EPSD	GDSC;CCLE	29.179	Down-regulation
Other_ULK_ULK_ULK1_ST	Q8NFG4	FLCN	O75385	ULK1	S62	S62G	62	Missense	central	0	yes	32.991	0.000	EPSD	GDSC;CCLE	29.179	Loss
Other_ULK_ULK_ULK1_ST	Q8NFG4	FLCN	O75385	ULK1	S62	A60V	60	Missense	proximal	-2	no	32.991	29.372	EPSD	GDSC;CCLE	29.179	Down-regulation
Other_ULK_ULK_ULK1_ST	Q8NFG4	FLCN	O75385	ULK1	S298	W299R	299	Missense	proximal	1	no	34.105	34.155	EPSD	GDSC;CCLE	29.179	Up-regulation
Other_ULK_ULK_ULK1_ST	Q8IVP5	FUNDC1	O75385	ULK1	S41	M44V	44	Missense	distal	3	no	26.409	30.424	EPSD	GDSC	29.179	Gain
Other_ULK_ULK_ULK1_ST	Q8TDY2	RB1CC1	O75385	ULK1	S222	E215Q	215	Missense	distal	-7	no	40.072	40.375	EPSD	GDSC;CCLE	29.179	Up-regulation
Other_ULK_ULK_ULK1_ST	Q8TDY2	RB1CC1	O75385	ULK1	S644	A641V	641	Missense	distal	-3	no	29.276	36.911	EPSD	GDSC	29.179	Up-regulation
Other_ULK_ULK_ULK1_ST	Q8TDY2	RB1CC1	O75385	ULK1	S836	S836A	836	Missense	central	0	yes	40.033	0.000	EPSD	GDSC	29.179	Loss
Other_ULK_ULK_ULK1_ST	Q8TDY2	RB1CC1	O75385	ULK1	S1222	Q1217K	1217	Missense	distal	-5	no	29.966	27.386	EPSD	GDSC;CCLE	29.179	Loss
Other_ULK_ULK_ULK1_ST	Q8TDY2	RB1CC1	O75385	ULK1	S1222	E1228K	1228	Missense	distal	6	no	29.966	29.184	EPSD	GDSC;CCLE	29.179	Down-regulation
Other_ULK_ULK_ULK1_ST	Q8TDY2	RB1CC1	O75385	ULK1	S1284	R1281S	1281	Missense	distal	-3	no	31.374	19.934	EPSD	GDSC;CCLE	29.179	Loss
Other_ULK_ULK_ULK1_ST	Q8TDY2	RB1CC1	O75385	ULK1	S1286	R1281S	1281	Missense	distal	-5	no	42.267	43.935	EPSD	GDSC;CCLE	29.179	Up-regulation
Other_ULK_ULK_ULK1_ST	Q8TDY2	RB1CC1	O75385	ULK1	S1323	M1317I	1317	Missense	distal	-6	no	32.559	30.901	PhosphoSitePlus;EPSD	GDSC	29.179	Down-regulation
Other_ULK_ULK_ULK1_ST	Q8TDY2	RB1CC1	O75385	ULK1	S1370	R1375*	1375	Missense	distal	5	no	29.155	30.498	EPSD	GDSC	29.179	Gain
Other_ULK_ULK_ULK1_ST	Q8TDY2	RB1CC1	O75385	ULK1	S1441	T1440R	1440	Missense	proximal	-1	no	30.632	30.916	EPSD	GDSC	29.179	Up-regulation
Other_ULK_ULK_ULK1_ST	O15027	SEC16A	O75385	ULK1	S153	H149P	149	Missense	distal	-4	no	36.992	33.737	EPSD	GDSC	29.179	Down-regulation
Other_ULK_ULK_ULK1_ST	O15027	SEC16A	O75385	ULK1	S346	H339R	339	Missense	distal	-7	no	32.548	31.472	EPSD	GDSC;CCLE	29.179	Down-regulation
Other_ULK_ULK_ULK1_ST	O15027	SEC16A	O75385	ULK1	S346	S342N	342	Missense	distal	-4	no	32.548	33.008	EPSD	GDSC;CCLE	29.179	Up-regulation
Other_ULK_ULK_ULK1_ST	O15027	SEC16A	O75385	ULK1	S358	P361H	361	Missense	distal	3	no	36.543	33.652	EPSD	GDSC;CCLE	29.179	Down-regulation
Other_ULK_ULK_ULK1_ST	O15027	SEC16A	O75385	ULK1	S668	S672P	672	Missense	distal	4	no	39.418	38.317	EPSD	GDSC;CCLE	29.179	Down-regulation
Other_ULK_ULK_ULK1_ST	O15027	SEC16A	O75385	ULK1	S668	S670P	670	Missense	proximal	2	no	39.418	37.991	EPSD	GDSC	29.179	Down-regulation
Other_ULK_ULK_ULK1_ST	O15027	SEC16A	O75385	ULK1	T812	A815T	815	Missense	distal	3	no	33.649	30.568	EPSD	GDSC	29.179	Down-regulation
Other_ULK_ULK_ULK1_ST	O15027	SEC16A	O75385	ULK1	S1045	A1047P	1047	Missense	proximal	2	no	30.862	30.347	EPSD	GDSC	29.179	Down-regulation
Other_ULK_ULK_ULK1_ST	O15027	SEC16A	O75385	ULK1	S1045	E1041K	1041	Missense	distal	-4	no	30.862	27.549	EPSD	GDSC;CCLE	29.179	Loss
Other_ULK_ULK_ULK1_ST	O15027	SEC16A	O75385	ULK1	S1045	S1045P	1045	Missense	central	0	yes	30.862	0.000	EPSD	GDSC	29.179	Loss
Other_ULK_ULK_ULK1_ST	O15027	SEC16A	O75385	ULK1	T1376	V1373M	1373	Missense	distal	-3	no	18.780	33.490	EPSD	GDSC	29.179	Gain
Other_ULK_ULK_ULK1_ST	O15027	SEC16A	O75385	ULK1	S1903	P1900L	1900	Missense	distal	-3	no	21.018	30.748	EPSD	GDSC;CCLE	29.179	Gain
Other_ULK_ULK_ULK1_ST	O15027	SEC16A	O75385	ULK1	S1905	P1900L	1900	Missense	distal	-5	no	48.132	49.984	EPSD	GDSC;CCLE	29.179	Up-regulation
Other_ULK_ULK_ULK1_ST	O15027	SEC16A	O75385	ULK1	S1905	T1898R	1898	Missense	distal	-7	no	48.132	46.770	EPSD	GDSC;CCLE	29.179	Down-regulation
Other_ULK_ULK_ULK1_ST	O15027	SEC16A	O75385	ULK1	S1905	T1898M	1898	Missense	distal	-7	no	48.132	47.155	EPSD	GDSC;CCLE	29.179	Down-regulation
Other_ULK_ULK_ULK1_ST	O15027	SEC16A	O75385	ULK1	S1905	S1903F	1903	Missense	proximal	-2	no	48.132	34.309	EPSD	GDSC;CCLE	29.179	Down-regulation
Other_ULK_ULK_ULK1_ST	O15027	SEC16A	O75385	ULK1	S1905	Q1899*	1899	Missense	distal	-6	no	48.132	44.161	EPSD	GDSC	29.179	Down-regulation
Other_ULK_ULK_ULK1_ST	O00560	SDCBP	O75385	ULK1	S6	M1L	1	Missense	distal	-5	no	29.653	26.447	EPSD;PhosphoSitePlus	GDSC	29.179	Loss
Other_ULK_ULK_ULK1_ST	O00560	SDCBP	O75385	ULK1	T206	M201I	201	Missense	distal	-5	no	33.749	31.326	EPSD	GDSC;CCLE	29.179	Down-regulation
Other_ULK_ULK_ULK1_ST	O00560	SDCBP	O75385	ULK1	T206	V209A	209	Missense	distal	3	no	33.749	34.105	EPSD	GDSC;CCLE	29.179	Up-regulation
Other_ULK_ULK_ULK1_ST	Q9Y4P1	ATG4B	O75385	ULK1	S316	E312K	312	Missense	distal	-4	no	41.974	38.662	PhosphoSitePlus	GDSC;CCLE	29.179	Down-regulation
Other_ULK_ULK_ULK1_ST	Q9Y4P1	ATG4B	O75385	ULK1	S316	L313I	313	Missense	distal	-3	no	41.974	39.452	PhosphoSitePlus	GDSC	29.179	Down-regulation
Other_ULK_ULK_ULK1_ST	Q8NEB9	PIK3C3	O75385	ULK1	S165	T166S	166	Missense	proximal	1	no	32.357	32.361	EPSD	GDSC;CCLE	29.179	Up-regulation
Other_ULK_ULK_ULK1_ST	Q8NEB9	PIK3C3	O75385	ULK1	S243	Y236D	236	Missense	distal	-7	no	28.940	30.639	EPSD	GDSC;CCLE	29.179	Gain
Other_ULK_ULK_ULK1_ST	Q8NEB9	PIK3C3	O75385	ULK1	S243	G240D	240	Missense	distal	-3	no	28.940	31.594	EPSD	GDSC;CCLE	29.179	Gain
Other_ULK_ULK_ULK1_ST	Q8NEB9	PIK3C3	O75385	ULK1	S261	M260T	260	Missense	proximal	-1	no	29.432	29.125	EPSD	GDSC;CCLE	29.179	Loss
Other_ULK_ULK_ULK1_ST	Q8NEB9	PIK3C3	O75385	ULK1	S261	K254E	254	Missense	distal	-7	no	29.432	31.129	EPSD	GDSC	29.179	Up-regulation
Other_ULK_ULK_ULK1_ST	A2RUS2	DENND3	O75385	ULK1	S472	V471G	471	Missense	proximal	-1	no	38.985	39.441	PhosphoSitePlus;EPSD	GDSC	29.179	Up-regulation
Other_ULK_ULK_ULK1_ST	A2RUS2	DENND3	O75385	ULK1	S472	R468C	468	Missense	distal	-4	no	38.985	34.600	PhosphoSitePlus;EPSD	GDSC	29.179	Down-regulation
Other_ULK_ULK_ULK1_ST	A2RUS2	DENND3	O75385	ULK1	S490	R492Q	492	Missense	proximal	2	no	36.893	37.139	EPSD;PhosphoSitePlus	GDSC	29.179	Up-regulation
Other_ULK_ULK_ULK1_ST	A2RUS2	DENND3	O75385	ULK1	T494	R492Q	492	Missense	proximal	-2	no	32.472	36.142	EPSD	GDSC	29.179	Up-regulation
Other_ULK_ULK_ULK1_ST	A2RUS2	DENND3	O75385	ULK1	S1175	T1172A	1172	Missense	distal	-3	no	29.960	28.764	EPSD	GDSC;CCLE	29.179	Loss
Other_ULK_ULK_ULK1_ST	Q13045	FLII	O75385	ULK1	S822	A817T	817	Missense	distal	-5	no	39.142	40.845	EPSD	GDSC	29.179	Up-regulation
CMGC_MAPK_JNK_MAPK9_ST	O95140	MFN2	P45984-2	MAPK9	S27	H20R	20	Missense	distal	-7	no	162.281	164.025	PhosphoSitePlus	GDSC;CCLE	140.458	Up-regulation
CMGC_MAPK_JNK_MAPK9_ST	P40763	STAT3	P45984-2	MAPK9	T714	C712Y	712	Missense	proximal	-2	no	149.040	146.490	EPSD	GDSC;CCLE	140.458	Down-regulation
TK_Tec_TEC_Y	Q06187	BTK	P42680	TEC	Y134	I132N	132	Missense	proximal	-2	no	165.688	252.815	EPSD	GDSC;CCLE	232.776	Gain
TK_Tec_TEC_Y	Q06187	BTK	P42680	TEC	Y551	D549A	549	Missense	proximal	-2	no	364.283	418.100	EPSD	GDSC;CCLE	232.776	Up-regulation
TK_Tec_TEC_Y	Q08881	ITK	P42680	TEC	Y146	C143Y	143	Missense	distal	-3	no	284.658	270.795	EPSD	GDSC;CCLE	232.776	Down-regulation
TK_Tec_TEC_Y	Q08881	ITK	P42680	TEC	Y146	N151H	151	Missense	distal	5	no	284.658	276.143	EPSD	GDSC;CCLE	232.776	Down-regulation
TK_Tec_TEC_Y	Q08881	ITK	P42680	TEC	Y180	V176A	176	Missense	distal	-4	no	342.208	351.491	PhosphoSitePlus	GDSC;CCLE	232.776	Up-regulation
TK_Tec_TEC_Y	Q08881	ITK	P42680	TEC	Y512	T518I	518	Missense	distal	6	no	406.594	399.077	EPSD	GDSC;CCLE	232.776	Down-regulation
TK_Tec_TEC_Y	Q08881	ITK	P42680	TEC	Y512	Q511*	511	Missense	proximal	-1	no	406.594	406.446	EPSD	GDSC	232.776	Down-regulation
TK_Tec_TEC_Y	Q08881	ITK	P42680	TEC	Y512	L508M	508	Missense	distal	-4	no	406.594	410.378	EPSD	GDSC;CCLE	232.776	Up-regulation
TK_Tec_TEC_Y	Q99952	PTPN18	P42680	TEC	Y281	E278Q	278	Missense	distal	-3	no	286.893	276.725	PhosphoSitePlus;EPSD	GDSC;CCLE	232.776	Down-regulation
TK_Tec_TEC_Y	Q99952	PTPN18	P42680	TEC	Y303	Y303S	303	Missense	central	0	yes	277.790	0.000	EPSD;PhosphoSitePlus	GDSC;CCLE	232.776	Loss
TK_Tec_TEC_Y	Q99952	PTPN18	P42680	TEC	Y314	D315N	315	Missense	proximal	1	no	260.056	259.391	EPSD	GDSC;CCLE	232.776	Down-regulation
TK_Tec_TEC_Y	P09038	FGF2	P42680	TEC	Y245	S250L	250	Missense	distal	5	no	293.041	264.281	EPSD	GDSC	232.776	Down-regulation
TK_Tec_TEC_Y	P09038	FGF2	P42680	TEC	Y257	S250L	250	Missense	distal	-7	no	352.187	328.919	EPSD	GDSC	232.776	Down-regulation
Other_TLK_TLK1_ST	Q99638	RAD9A	Q9UKI8	TLK1	S270	S277F	277	Missense	distal	7	no	2.666	2.588	EPSD	GDSC;CCLE	2.233	Down-regulation
Other_TLK_TLK1_ST	Q99638	RAD9A	Q9UKI8	TLK1	T355	P357Q	357	Missense	proximal	2	no	6.265	6.258	EPSD;PhosphoSitePlus	GDSC;CCLE	2.233	Down-regulation
Other_TLK_TLK1_ST	Q99638	RAD9A	Q9UKI8	TLK1	T355	S350G	350	Missense	distal	-5	no	6.265	6.198	EPSD;PhosphoSitePlus	GDSC;CCLE	2.233	Down-regulation
Other_TLK_TLK1_ST	Q96PY6	NEK1	Q9UKI8	TLK1	S219	L225F	225	Missense	distal	6	no	2.202	2.315	EPSD	GDSC;CCLE	2.233	Gain
CMGC_CDK_CDC2_CDK1_ST	Q13049	TRIM32	P06493	CDK1	S328	S335N	335	Missense	distal	7	no	3.556	3.563	EPSD;PhosphoSitePlus	GDSC;CCLE	3.158	Up-regulation
CMGC_CDK_CDC2_CDK1_ST	Q13049	TRIM32	P06493	CDK1	S339	P346H	346	Missense	distal	7	no	3.220	3.227	EPSD;PhosphoSitePlus	GDSC	3.158	Up-regulation
CMGC_CDK_CDC2_CDK1_ST	Q13049	TRIM32	P06493	CDK1	S339	S335N	335	Missense	distal	-4	no	3.220	3.148	EPSD;PhosphoSitePlus	GDSC;CCLE	3.158	Loss
CMGC_CDK_CDC2_CDK1_ST	P11388	TOP2A	P06493	CDK1	S1393	S1392*	1392	Missense	proximal	-1	no	2.725	3.210	EPSD;PhosphoSitePlus	GDSC	3.158	Gain
CMGC_CDK_CDC2_CDK1_ST	Q99638	RAD9A	P06493	CDK1	T292	P285R	285	Missense	distal	-7	no	3.534	3.539	EPSD;PhosphoSitePlus	GDSC;CCLE	3.158	Up-regulation
CMGC_CDK_CDC2_CDK1_ST	Q99638	RAD9A	P06493	CDK1	S375	R374C	374	Missense	proximal	-1	no	3.385	3.440	EPSD	GDSC;CCLE	3.158	Up-regulation
CMGC_CDK_CDC2_CDK1_ST	Q99638	RAD9A	P06493	CDK1	S375	P376H	376	Missense	proximal	1	no	3.385	0.701	EPSD	GDSC;CCLE	3.158	Loss
CMGC_CDK_CDC2_CDK1_ST	Q99638	RAD9A	P06493	CDK1	S375	P379L	379	Missense	distal	4	no	3.385	3.263	EPSD	GDSC;CCLE	3.158	Down-regulation
CMGC_CDK_CDC2_CDK1_ST	Q99638	RAD9A	P06493	CDK1	S375	I369F	369	Missense	distal	-6	no	3.385	3.387	EPSD	GDSC	3.158	Up-regulation
CMGC_CDK_CDC2_CDK1_ST	Q99638	RAD9A	P06493	CDK1	S380	R374C	374	Missense	distal	-6	no	3.427	3.437	EPSD	GDSC;CCLE	3.158	Up-regulation
CMGC_CDK_CDC2_CDK1_ST	Q99638	RAD9A	P06493	CDK1	S380	P376H	376	Missense	distal	-4	no	3.427	3.408	EPSD	GDSC;CCLE	3.158	Down-regulation
CMGC_CDK_CDC2_CDK1_ST	Q99638	RAD9A	P06493	CDK1	S380	P379L	379	Missense	proximal	-1	no	3.427	3.578	EPSD	GDSC;CCLE	3.158	Up-regulation
CMGC_CDK_CDC2_CDK1_ST	P49792	RANBP2	P06493	CDK1	T19	R23G	23	Missense	distal	4	no	3.188	3.062	EPSD	GDSC;CCLE	3.158	Loss
CMGC_CDK_CDC2_CDK1_ST	P49792	RANBP2	P06493	CDK1	S394	D387N	387	Missense	distal	-7	no	3.287	3.288	EPSD	GDSC;CCLE	3.158	Up-regulation
CMGC_CDK_CDC2_CDK1_ST	P49792	RANBP2	P06493	CDK1	S700	E705G	705	Missense	distal	5	no	3.234	3.337	EPSD	GDSC;CCLE	3.158	Up-regulation
CMGC_CDK_CDC2_CDK1_ST	P49792	RANBP2	P06493	CDK1	T1255	R1262K	1262	Missense	distal	7	no	3.395	3.396	EPSD	GDSC;CCLE	3.158	Up-regulation
CMGC_CDK_CDC2_CDK1_ST	P49792	RANBP2	P06493	CDK1	T1412	W1419L	1419	Missense	distal	7	no	3.716	3.730	EPSD	GDSC;CCLE	3.158	Up-regulation
CMGC_CDK_CDC2_CDK1_ST	P49792	RANBP2	P06493	CDK1	S1573	P1569L	1569	Missense	distal	-4	no	3.199	3.055	EPSD	GDSC;CCLE	3.158	Loss
CMGC_CDK_CDC2_CDK1_ST	P49792	RANBP2	P06493	CDK1	T1761	A1763T	1763	Missense	proximal	2	no	3.468	3.474	EPSD	GDSC;CCLE	3.158	Up-regulation
CMGC_CDK_CDC2_CDK1_ST	P49792	RANBP2	P06493	CDK1	S1869	H1863L	1863	Missense	distal	-6	no	3.179	3.195	EPSD	GDSC;CCLE	3.158	Up-regulation
CMGC_CDK_CDC2_CDK1_ST	P49792	RANBP2	P06493	CDK1	T2128	E2134K	2134	Missense	distal	6	no	3.509	3.512	EPSD	GDSC;CCLE	3.158	Up-regulation
CMGC_CDK_CDC2_CDK1_ST	P49792	RANBP2	P06493	CDK1	S2280	P2277L	2277	Missense	distal	-3	no	3.534	3.502	EPSD;PhosphoSitePlus	GDSC;CCLE	3.158	Down-regulation
CMGC_CDK_CDC2_CDK1_ST	P49792	RANBP2	P06493	CDK1	S2280	A2282T	2282	Missense	proximal	2	no	3.534	3.540	EPSD;PhosphoSitePlus	GDSC;CCLE	3.158	Up-regulation
CMGC_CDK_CDC2_CDK1_ST	P49792	RANBP2	P06493	CDK1	T2387	N2394T	2394	Missense	distal	7	no	3.318	3.314	EPSD	GDSC	3.158	Down-regulation
CMGC_CDK_CDC2_CDK1_ST	P49792	RANBP2	P06493	CDK1	T2613	K2620N	2620	Missense	distal	7	no	3.749	3.746	EPSD	GDSC;CCLE	3.158	Down-regulation
CMGC_CDK_CDC2_CDK1_ST	Q07820	MCL1	P06493	CDK1	S121	M120V	120	Missense	proximal	-1	no	3.429	3.486	EPSD	GDSC	3.158	Up-regulation
CMGC_CDK_CDC2_CDK1_ST	Q14980	NUMA1	P06493	CDK1	S77	P75T	75	Missense	proximal	-2	no	3.155	3.242	EPSD	GDSC;CCLE	3.158	Gain
CMGC_CDK_CDC2_CDK1_ST	Q14980	NUMA1	P06493	CDK1	S112	M108I	108	Missense	distal	-4	no	3.226	3.163	EPSD	GDSC	3.158	Down-regulation
CMGC_CDK_CDC2_CDK1_ST	Q96FF9	CDCA5	P06493	CDK1	S21	G16E	16	Missense	distal	-5	no	3.327	3.255	EPSD;PhosphoSitePlus	GDSC	3.158	Down-regulation
CMGC_CDK_CDC2_CDK1_ST	Q99728	BARD1	P06493	CDK1	S288	K292E	292	Missense	distal	4	no	3.330	3.299	EPSD;PhosphoSitePlus	GDSC;CCLE	3.158	Down-regulation
CMGC_CDK_CDC2_CDK1_ST	P21333	FLNA	P06493	CDK1	S2224	Q2219R	2219	Missense	distal	-5	no	3.485	3.517	EPSD	GDSC;CCLE	3.158	Up-regulation
CMGC_CDK_CDC2_CDK1_ST	P21333	FLNA	P06493	CDK1	S2640	P2638Q	2638	Missense	proximal	-2	no	3.246	3.386	EPSD	GDSC;CCLE	3.158	Up-regulation
CMGC_CDK_CDC2_CDK1_ST	P08047	SP1	P06493	CDK1	T739	G736V	736	Missense	distal	-3	no	3.132	3.167	EPSD;PhosphoSitePlus	GDSC;CCLE	3.158	Gain
CMGC_CDK_CDC2_CDK1_ST	P08047	SP1	P06493	CDK1	T739	A738T	738	Missense	proximal	-1	no	3.132	3.159	EPSD;PhosphoSitePlus	GDSC;CCLE	3.158	Gain
CMGC_CDK_CDC2_CDK1_ST	P19338	NCL	P06493	CDK1	T113	G115D	115	Missense	proximal	2	no	3.440	3.427	EPSD	GDSC;CCLE	3.158	Down-regulation
CMGC_CDK_CDC2_CDK1_ST	P19338	NCL	P06493	CDK1	T121	G115D	115	Missense	distal	-6	no	3.354	3.341	PhosphoSitePlus;EPSD	GDSC;CCLE	3.158	Down-regulation
CMGC_CDK_CDC2_CDK1_ST	P19338	NCL	P06493	CDK1	S563	R567I	567	Missense	distal	4	no	3.481	3.369	EPSD	GDSC;CCLE	3.158	Down-regulation
CMGC_CDK_CDC2_CDK1_ST	Q9HCH0	NCKAP5L	P06493	CDK1	S818	P819L	819	Missense	proximal	1	no	3.462	-0.224	EPSD	GDSC;CCLE	3.158	Loss
CMGC_CDK_CDC2_CDK1_ST	Q9HCH0	NCKAP5L	P06493	CDK1	S818	P819S	819	Missense	proximal	1	no	3.462	0.277	EPSD	GDSC;CCLE	3.158	Loss
CMGC_CDK_CDC2_CDK1_ST	Q9HCH0	NCKAP5L	P06493	CDK1	S944	G943R	943	Missense	proximal	-1	no	3.831	3.673	EPSD	GDSC;CCLE	3.158	Down-regulation
CMGC_CDK_CDC2_CDK1_ST	P18031	PTPN1	P06493	CDK1	S386	A382D	382	Missense	distal	-4	no	3.252	3.221	PhosphoSitePlus	GDSC	3.158	Down-regulation
CMGC_CDK_CDC2_CDK1_ST	Q96R06	SPAG5	P06493	CDK1	S12	K19N	19	Missense	distal	7	no	3.675	3.672	EPSD	GDSC;CCLE	3.158	Down-regulation
CMGC_CDK_CDC2_CDK1_ST	Q96R06	SPAG5	P06493	CDK1	T111	K113T	113	Missense	proximal	2	no	3.377	3.372	EPSD	GDSC;CCLE	3.158	Down-regulation
CMGC_CDK_CDC2_CDK1_ST	Q96R06	SPAG5	P06493	CDK1	S249	L246V	246	Missense	distal	-3	no	3.678	3.690	EPSD;PhosphoSitePlus	GDSC;CCLE	3.158	Up-regulation
CMGC_CDK_CDC2_CDK1_ST	Q96R06	SPAG5	P06493	CDK1	T963	P960L	960	Missense	distal	-3	no	3.210	3.179	EPSD	GDSC;CCLE	3.158	Down-regulation
CMGC_CDK_CDC2_CDK1_ST	Q9NTI5	PDS5B	P06493	CDK1	S1283	E1276Q	1276	Missense	distal	-7	no	3.284	3.322	EPSD	GDSC;CCLE	3.158	Up-regulation
CMGC_CDK_CDC2_CDK1_ST	Q13586	STIM1	P06493	CDK1	S486	V485M	485	Missense	proximal	-1	no	3.259	3.202	EPSD	GDSC;CCLE	3.158	Down-regulation
CMGC_CDK_CDC2_CDK1_ST	Q9Y6I3	EPN1	P06493	CDK1	S454	P457S	457	Missense	distal	3	no	3.137	3.187	EPSD	GDSC	3.158	Gain
CMGC_CDK_CDC2_CDK1_ST	Q9Y6I3	EPN1	P06493	CDK1	T462	P457L	457	Missense	distal	-5	no	3.734	3.855	EPSD	GDSC	3.158	Up-regulation
CMGC_CDK_CDC2_CDK1_ST	Q9Y6I3	EPN1	P06493	CDK1	T462	P457S	457	Missense	distal	-5	no	3.734	3.712	EPSD	GDSC	3.158	Down-regulation
CMGC_CDK_CDC2_CDK1_ST	Q9Y6I3	EPN1	P06493	CDK1	T464	P457L	457	Missense	distal	-7	no	3.781	3.621	EPSD	GDSC	3.158	Down-regulation
CMGC_CDK_CDC2_CDK1_ST	Q9Y6I3	EPN1	P06493	CDK1	T464	P457S	457	Missense	distal	-7	no	3.781	3.821	EPSD	GDSC	3.158	Up-regulation
CMGC_CDK_CDC2_CDK1_ST	Q14202	ZMYM3	P06493	CDK1	S51	P48S	48	Missense	distal	-3	no	3.634	3.633	EPSD	GDSC;CCLE	3.158	Down-regulation
CMGC_CDK_CDC2_CDK1_ST	Q14202	ZMYM3	P06493	CDK1	T62	T62A	62	Missense	central	0	yes	3.497	0.000	EPSD	GDSC;CCLE	3.158	Loss
CMGC_CDK_CDC2_CDK1_ST	Q14202	ZMYM3	P06493	CDK1	T62	E67K	67	Missense	distal	5	no	3.497	3.449	EPSD	GDSC;CCLE	3.158	Down-regulation
CMGC_CDK_CDC2_CDK1_ST	Q14202	ZMYM3	P06493	CDK1	S91	V95G	95	Missense	distal	4	no	3.201	3.169	EPSD	GDSC	3.158	Down-regulation
CMGC_CDK_CDC2_CDK1_ST	Q14202	ZMYM3	P06493	CDK1	S91	A89T	89	Missense	proximal	-2	no	3.201	3.281	EPSD	GDSC	3.158	Up-regulation
CMGC_CDK_CDC2_CDK1_ST	P46060	RANGAP1	P06493	CDK1	T409	S411*	411	Missense	proximal	2	no	3.255	3.304	PhosphoSitePlus	GDSC	3.158	Up-regulation
CMGC_CDK_CDC2_CDK1_ST	P46060	RANGAP1	P06493	CDK1	S428	V425M	425	Missense	distal	-3	no	3.161	3.167	EPSD	GDSC;CCLE	3.158	Up-regulation
CMGC_CDK_CDC2_CDK1_ST	Q9UQ35	SRRM2	P06493	CDK1	T111	A117V	117	Missense	distal	6	no	3.260	3.212	EPSD	GDSC	3.158	Down-regulation
CMGC_CDK_CDC2_CDK1_ST	Q9UQ35	SRRM2	P06493	CDK1	S353	G360C	360	Missense	distal	7	no	3.215	3.203	EPSD	GDSC;CCLE	3.158	Down-regulation
CMGC_CDK_CDC2_CDK1_ST	Q9UQ35	SRRM2	P06493	CDK1	S1311	E1313Q	1313	Missense	proximal	2	no	3.583	3.576	EPSD	GDSC;CCLE	3.158	Down-regulation
CMGC_CDK_CDC2_CDK1_ST	Q9UQ35	SRRM2	P06493	CDK1	S1320	E1313Q	1313	Missense	distal	-7	no	3.403	3.440	EPSD	GDSC;CCLE	3.158	Up-regulation
CMGC_CDK_CDC2_CDK1_ST	Q9UQ35	SRRM2	P06493	CDK1	S2123	P2120L	2120	Missense	distal	-3	no	3.432	3.400	EPSD	GDSC;CCLE	3.158	Down-regulation
CMGC_CDK_CDC2_CDK1_ST	Q9UQ35	SRRM2	P06493	CDK1	T2125	P2120L	2120	Missense	distal	-5	no	3.266	3.387	EPSD	GDSC;CCLE	3.158	Up-regulation
CMGC_CDK_CDC2_CDK1_ST	P30260	CDC27	P06493	CDK1	T68	K72T	72	Missense	distal	4	no	3.903	3.924	EPSD	GDSC;CCLE	3.158	Up-regulation
CMGC_CDK_CDC2_CDK1_ST	P30260	CDC27	P06493	CDK1	T279	A274P	274	Missense	distal	-5	no	3.140	3.186	EPSD	GDSC	3.158	Gain
CMGC_CDK_CDC2_CDK1_ST	P38936	CDKN1A	P06493	CDK1	T57	E56*	56	Missense	proximal	-1	no	3.807	4.198	EPSD	GDSC	3.158	Up-regulation
CMGC_CDK_CDC2_CDK1_ST	Q32P44	EML3	P06493	CDK1	T494	S488R	488	Missense	distal	-6	no	3.545	3.552	EPSD	GDSC;CCLE	3.158	Up-regulation
CMGC_CDK_CDC2_CDK1_ST	Q32P44	EML3	P06493	CDK1	T881	P886L	886	Missense	distal	5	no	3.120	3.305	PhosphoSitePlus	GDSC;CCLE	3.158	Gain
CMGC_CDK_CDC2_CDK1_ST	Q32P44	EML3	P06493	CDK1	S889	P886L	886	Missense	distal	-3	no	3.661	3.629	EPSD	GDSC;CCLE	3.158	Down-regulation
CMGC_CDK_CDC2_CDK1_ST	Q9H1A4	ANAPC1	P06493	CDK1	T291	T291P	291	Missense	central	0	yes	3.507	0.000	EPSD;PhosphoSitePlus	GDSC;CCLE	3.158	Loss
CMGC_CDK_CDC2_CDK1_ST	Q9H1A4	ANAPC1	P06493	CDK1	T291	T297A	297	Missense	distal	6	no	3.507	3.516	EPSD;PhosphoSitePlus	GDSC;CCLE	3.158	Up-regulation
CMGC_CDK_CDC2_CDK1_ST	Q9H1A4	ANAPC1	P06493	CDK1	T537	V535D	535	Missense	proximal	-2	no	3.205	3.178	EPSD;PhosphoSitePlus	GDSC;CCLE	3.158	Down-regulation
CMGC_CDK_CDC2_CDK1_ST	Q9H1A4	ANAPC1	P06493	CDK1	T537	L541V	541	Missense	distal	4	no	3.205	3.248	EPSD;PhosphoSitePlus	GDSC;CCLE	3.158	Up-regulation
CMGC_CDK_CDC2_CDK1_ST	Q8IZD2	KMT2E	P06493	CDK1	S837	S837P	837	Missense	central	0	yes	3.275	0.000	EPSD	GDSC	3.158	Loss
CMGC_CDK_CDC2_CDK1_ST	Q8IZD2	KMT2E	P06493	CDK1	T904	P905A	905	Missense	proximal	1	no	3.351	2.462	EPSD	GDSC	3.158	Loss
CMGC_CDK_CDC2_CDK1_ST	Q8IZD2	KMT2E	P06493	CDK1	T1088	Q1092*	1092	Missense	distal	4	no	3.506	3.276	EPSD	GDSC	3.158	Down-regulation
CMGC_CDK_CDC2_CDK1_ST	Q8IZD2	KMT2E	P06493	CDK1	S1444	P1443L	1443	Missense	proximal	-1	no	3.096	3.246	EPSD	GDSC;CCLE	3.158	Gain
CMGC_CDK_CDC2_CDK1_ST	Q7Z3J3	RGPD4	P06493	CDK1	S1301	S1305A	1305	Missense	distal	4	no	3.148	3.208	EPSD	GDSC;CCLE	3.158	Gain
CMGC_CDK_CDC2_CDK1_ST	Q7Z3J3	RGPD4	P06493	CDK1	S1305	S1305A	1305	Missense	central	0	yes	3.498	0.000	EPSD	GDSC;CCLE	3.158	Loss
CMGC_CDK_CDC2_CDK1_ST	Q7Z3J3	RGPD4	P06493	CDK1	T1529	T1530P	1530	Missense	proximal	1	no	0.886	3.320	EPSD	GDSC	3.158	Gain
CMGC_CDK_CDC2_CDK1_ST	Q7Z3J3	RGPD4	P06493	CDK1	T1638	T1635K	1635	Missense	distal	-3	no	3.440	3.397	EPSD	GDSC	3.158	Down-regulation
CMGC_CDK_CDC2_CDK1_ST	Q16659	MAPK6	P06493	CDK1	S705	M702V	702	Missense	distal	-3	no	3.186	3.180	EPSD;PhosphoSitePlus	GDSC;CCLE	3.158	Down-regulation
CMGC_CDK_CDC2_CDK1_ST	Q13428	TCOF1	P06493	CDK1	S1378	A1375V	1375	Missense	distal	-3	no	3.685	3.623	EPSD	GDSC;CCLE	3.158	Down-regulation
CMGC_CDK_CDC2_CDK1_ST	Q13428	TCOF1	P06493	CDK1	S1378	G1373W	1373	Missense	distal	-5	no	3.685	3.641	EPSD	GDSC	3.158	Down-regulation
CMGC_CDK_CDC2_CDK1_ST	Q96GX5	MASTL	P06493	CDK1	T710	H707L	707	Missense	distal	-3	no	3.401	3.385	EPSD	GDSC	3.158	Down-regulation
CMGC_CDK_CDC2_CDK1_ST	A6NKT7	RGPD3	P06493	CDK1	T1153	R1146*	1146	Missense	distal	-7	no	3.362	3.023	EPSD	GDSC	3.158	Loss
CMGC_CDK_CDC2_CDK1_ST	A6NKT7	RGPD3	P06493	CDK1	T1153	R1146P	1146	Missense	distal	-7	no	3.362	3.357	EPSD	GDSC	3.158	Down-regulation
CMGC_CDK_CDC2_CDK1_ST	A6NKT7	RGPD3	P06493	CDK1	T1153	E1158*	1158	Missense	distal	5	no	3.362	3.634	EPSD	GDSC	3.158	Up-regulation
CMGC_CDK_CDC2_CDK1_ST	A6NKT7	RGPD3	P06493	CDK1	T1153	A1157D	1157	Missense	distal	4	no	3.362	3.257	EPSD	GDSC	3.158	Down-regulation
CMGC_CDK_CDC2_CDK1_ST	A6NKT7	RGPD3	P06493	CDK1	T1412	S1416T	1416	Missense	distal	4	no	3.322	3.330	EPSD	GDSC	3.158	Up-regulation
CMGC_CDK_CDC2_CDK1_ST	A6NKT7	RGPD3	P06493	CDK1	T1412	N1419T	1419	Missense	distal	7	no	3.322	3.318	EPSD	GDSC	3.158	Down-regulation
CMGC_CDK_CDC2_CDK1_ST	A6NKT7	RGPD3	P06493	CDK1	T1412	L1405F	1405	Missense	distal	-7	no	3.322	3.376	EPSD	GDSC	3.158	Up-regulation
CMGC_CDK_CDC2_CDK1_ST	A6NKT7	RGPD3	P06493	CDK1	T1475	E1469K	1469	Missense	distal	-6	no	3.386	3.388	EPSD	GDSC	3.158	Up-regulation
CMGC_CDK_CDC2_CDK1_ST	A6NKT7	RGPD3	P06493	CDK1	T1475	H1477N	1477	Missense	proximal	2	no	3.386	3.380	EPSD	GDSC	3.158	Down-regulation
CMGC_CDK_CDC2_CDK1_ST	A6NKT7	RGPD3	P06493	CDK1	T1638	L1645F	1645	Missense	distal	7	no	3.471	3.463	EPSD	GDSC;CCLE	3.158	Down-regulation
CMGC_CDK_CDC2_CDK1_ST	Q12778	FOXO1	P06493	CDK1	S218	L219P	219	Missense	proximal	1	no	-0.266	3.421	EPSD	GDSC;CCLE	3.158	Gain
CMGC_CDK_CDC2_CDK1_ST	Q12778	FOXO1	P06493	CDK1	S329	T333A	333	Missense	distal	4	no	3.261	3.313	EPSD	GDSC;CCLE	3.158	Up-regulation
CMGC_CDK_CDC2_CDK1_ST	Q86WB0	ZC3HC1	P06493	CDK1	S24	P29S	29	Missense	distal	5	no	3.407	3.378	EPSD	GDSC	3.158	Down-regulation
CMGC_CDK_CDC2_CDK1_ST	O95235	KIF20A	P06493	CDK1	S21	S26F	26	Missense	distal	5	no	3.029	3.195	EPSD;PhosphoSitePlus	GDSC	3.158	Gain
CMGC_CDK_CDC2_CDK1_ST	P30304	CDC25A	P06493	CDK1	S321	A319V	319	Missense	proximal	-2	no	3.190	3.355	EPSD	GDSC;CCLE	3.158	Up-regulation
CMGC_CDK_CDC2_CDK1_ST	P30304	CDC25A	P06493	CDK1	S321	Q314*	314	Missense	distal	-7	no	3.190	2.845	EPSD	GDSC	3.158	Loss
CMGC_CDK_CDC2_CDK1_ST	Q15398	DLGAP5	P06493	CDK1	T338	R331T	331	Missense	distal	-7	no	3.161	3.217	EPSD	GDSC;CCLE	3.158	Up-regulation
CMGC_CDK_CDC2_CDK1_ST	Q15398	DLGAP5	P06493	CDK1	S767	P768S	768	Missense	proximal	1	no	3.386	0.202	EPSD	GDSC	3.158	Loss
CMGC_CDK_CDC2_CDK1_ST	P52948	NUP98	P06493	CDK1	S839	S839*	839	Missense	central	0	yes	3.422	0.000	EPSD	GDSC	3.158	Loss
CMGC_CDK_CDC2_CDK1_ST	O15350	TP73	P06493	CDK1	T167	T167P	167	Missense	central	0	yes	3.416	0.000	EPSD	GDSC	3.158	Loss
CMGC_CDK_CDC2_CDK1_ST	Q09666	AHNAK	P06493	CDK1	S93	P96L	96	Missense	distal	3	no	3.165	3.033	EPSD	GDSC;CCLE	3.158	Loss
CMGC_CDK_CDC2_CDK1_ST	Q09666	AHNAK	P06493	CDK1	S93	P96H	96	Missense	distal	3	no	3.165	3.194	EPSD	GDSC;CCLE	3.158	Up-regulation
CMGC_CDK_CDC2_CDK1_ST	Q09666	AHNAK	P06493	CDK1	T324	R320H	320	Missense	distal	-4	no	3.806	3.802	EPSD	GDSC	3.158	Down-regulation
CMGC_CDK_CDC2_CDK1_ST	Q09666	AHNAK	P06493	CDK1	T490	T486A	486	Missense	distal	-4	no	4.009	3.974	EPSD	GDSC;CCLE	3.158	Down-regulation
CMGC_CDK_CDC2_CDK1_ST	Q09666	AHNAK	P06493	CDK1	T2309	T2309A	2309	Missense	central	0	yes	3.454	0.000	EPSD	GDSC;CCLE	3.158	Loss
CMGC_CDK_CDC2_CDK1_ST	Q09666	AHNAK	P06493	CDK1	T2309	E2304D	2304	Missense	distal	-5	no	3.454	3.445	EPSD	GDSC;CCLE	3.158	Down-regulation
CMGC_CDK_CDC2_CDK1_ST	Q09666	AHNAK	P06493	CDK1	T2832	T2832I	2832	Missense	central	0	yes	3.419	0.000	EPSD	GDSC;CCLE	3.158	Loss
CMGC_CDK_CDC2_CDK1_ST	Q09666	AHNAK	P06493	CDK1	S3412	M3405V	3405	Missense	distal	-7	no	3.740	3.683	EPSD	GDSC;CCLE	3.158	Down-regulation
CMGC_CDK_CDC2_CDK1_ST	Q09666	AHNAK	P06493	CDK1	S4516	D4523N	4523	Missense	distal	7	no	3.413	3.407	EPSD	GDSC;CCLE	3.158	Down-regulation
CMGC_CDK_CDC2_CDK1_ST	Q09666	AHNAK	P06493	CDK1	S4516	Q4518K	4518	Missense	proximal	2	no	3.413	3.415	EPSD	GDSC;CCLE	3.158	Up-regulation
CMGC_CDK_CDC2_CDK1_ST	Q09666	AHNAK	P06493	CDK1	S4986	K4979E	4979	Missense	distal	-7	no	3.325	3.370	EPSD	GDSC;CCLE	3.158	Up-regulation
CMGC_CDK_CDC2_CDK1_ST	Q09666	AHNAK	P06493	CDK1	S5110	L5117P	5117	Missense	distal	7	no	3.499	3.471	EPSD	GDSC;CCLE	3.158	Down-regulation
CMGC_CDK_CDC2_CDK1_ST	Q09666	AHNAK	P06493	CDK1	S5731	A5734T	5734	Missense	distal	3	no	3.540	3.453	EPSD	GDSC;CCLE	3.158	Down-regulation
CMGC_CDK_CDC2_CDK1_ST	Q09666	AHNAK	P06493	CDK1	S5763	E5760K	5760	Missense	distal	-3	no	3.373	3.362	PhosphoSitePlus	GDSC;CCLE	3.158	Down-regulation
CMGC_CDK_CDC2_CDK1_ST	P55211	CASP9	P06493	CDK1	T125	P123L	123	Missense	proximal	-2	no	3.655	3.828	PhosphoSitePlus	GDSC	3.158	Up-regulation
CMGC_CDK_CDC2_CDK1_ST	P55211	CASP9	P06493	CDK1	S302	E306K	306	Missense	distal	4	no	3.188	3.219	EPSD	GDSC;CCLE	3.158	Up-regulation
CMGC_CDK_CDC2_CDK1_ST	Q13042	CDC16	P06493	CDK1	T589	S592Y	592	Missense	distal	3	no	3.383	3.308	EPSD	GDSC;CCLE	3.158	Down-regulation
CMGC_CDK_CDC2_CDK1_ST	O94782	USP1	P06493	CDK1	S398	L396H	396	Missense	proximal	-2	no	3.359	3.333	EPSD	GDSC;CCLE	3.158	Down-regulation
CMGC_CDK_CDC2_CDK1_ST	O94782	USP1	P06493	CDK1	T558	L560V	560	Missense	proximal	2	no	3.207	3.201	EPSD	GDSC	3.158	Down-regulation
CMGC_CDK_CDC2_CDK1_ST	O94782	USP1	P06493	CDK1	S768	L764V	764	Missense	distal	-4	no	3.795	3.868	EPSD	GDSC;CCLE	3.158	Up-regulation
CMGC_CDK_CDC2_CDK1_ST	Q92574	TSC1	P06493	CDK1	T417	T417I	417	Missense	central	0	yes	3.283	0.000	EPSD;PhosphoSitePlus	GDSC;CCLE	3.158	Loss
CMGC_CDK_CDC2_CDK1_ST	Q92574	TSC1	P06493	CDK1	S644	M646V	646	Missense	proximal	2	no	3.512	3.520	EPSD	GDSC	3.158	Up-regulation
CMGC_CDK_CDC2_CDK1_ST	Q92574	TSC1	P06493	CDK1	S682	I688F	688	Missense	distal	6	no	3.246	3.244	EPSD	GDSC;CCLE	3.158	Down-regulation
CMGC_CDK_CDC2_CDK1_ST	Q92574	TSC1	P06493	CDK1	S1141	P1143T	1143	Missense	proximal	2	no	3.628	3.627	EPSD	GDSC	3.158	Down-regulation
CMGC_CDK_CDC2_CDK1_ST	Q92574	TSC1	P06493	CDK1	S1141	P1142H	1142	Missense	proximal	1	no	3.628	0.944	EPSD	GDSC	3.158	Loss
CMGC_CDK_CDC2_CDK1_ST	Q92574	TSC1	P06493	CDK1	T1144	P1143T	1143	Missense	proximal	-1	no	3.323	3.245	EPSD	GDSC	3.158	Down-regulation
CMGC_CDK_CDC2_CDK1_ST	Q92574	TSC1	P06493	CDK1	T1144	P1142H	1142	Missense	proximal	-2	no	3.323	3.471	EPSD	GDSC	3.158	Up-regulation
CMGC_CDK_CDC2_CDK1_ST	Q99661	KIF2C	P06493	CDK1	T537	R540H	540	Missense	distal	3	no	3.173	3.080	PhosphoSitePlus	GDSC;CCLE	3.158	Loss
CMGC_CDK_CDC2_CDK1_ST	Q99661	KIF2C	P06493	CDK1	T537	K534E	534	Missense	distal	-3	no	3.173	3.184	PhosphoSitePlus	GDSC;CCLE	3.158	Up-regulation
CMGC_CDK_CDC2_CDK1_ST	Q01167	FOXK2	P06493	CDK1	S170	K173N	173	Missense	distal	3	no	3.505	3.457	EPSD	GDSC;CCLE	3.158	Down-regulation
CMGC_CDK_CDC2_CDK1_ST	Q01167	FOXK2	P06493	CDK1	S199	S199P	199	Missense	central	0	yes	3.231	0.000	EPSD	GDSC;CCLE	3.158	Loss
CMGC_CDK_CDC2_CDK1_ST	Q9NZJ0	DTL	P06493	CDK1	T464	L460F	460	Missense	distal	-4	no	3.142	3.190	PhosphoSitePlus	GDSC;CCLE	3.158	Gain
CMGC_CDK_CDC2_CDK1_ST	Q9NZJ0	DTL	P06493	CDK1	S539	Q540P	540	Missense	proximal	1	no	1.087	3.510	EPSD	GDSC;CCLE	3.158	Gain
CMGC_CDK_CDC2_CDK1_ST	P30307	CDC25C	P06493	CDK1	S472	M471T	471	Missense	proximal	-1	no	3.626	3.510	EPSD	GDSC;CCLE	3.158	Down-regulation
CMGC_CDK_CDC2_CDK1_ST	O00418	EEF2K	P06493	CDK1	S74	Y69H	69	Missense	distal	-5	no	3.347	3.319	EPSD	GDSC;CCLE	3.158	Down-regulation
CMGC_CDK_CDC2_CDK1_ST	Q9BXS6	NUSAP1	P06493	CDK1	T300	P301S	301	Missense	proximal	1	no	3.540	0.356	PhosphoSitePlus;EPSD	GDSC;CCLE	3.158	Loss
CMGC_CDK_CDC2_CDK1_ST	P33316	DUT	P06493	CDK1	S88	T95P	95	Missense	distal	7	no	3.452	3.451	EPSD	GDSC	3.158	Down-regulation
CMGC_CDK_CDC2_CDK1_ST	Q9BW19	KIFC1	P06493	CDK1	T477	R478P	478	Missense	proximal	1	no	-0.336	3.273	EPSD	GDSC;CCLE	3.158	Gain
CMGC_CDK_CDC2_CDK1_ST	Q16665	HIF1A	P06493	CDK1	S510	Q508*	508	Missense	proximal	-2	no	3.732	3.950	EPSD	GDSC	3.158	Up-regulation
CMGC_CDK_CDC2_CDK1_ST	Q01094	E2F1	P06493	CDK1	T311	G309E	309	Missense	proximal	-2	no	3.452	3.401	EPSD	GDSC;CCLE	3.158	Down-regulation
CMGC_CDK_CDC2_CDK1_ST	Q01094	E2F1	P06493	CDK1	S403	A408T	408	Missense	distal	5	no	3.534	3.597	EPSD	GDSC;CCLE	3.158	Up-regulation
CMGC_CDK_CDC2_CDK1_ST	Q04637	EIF4G1	P06493	CDK1	S263	P264L	264	Missense	proximal	1	no	3.571	-0.115	EPSD	GDSC	3.158	Loss
CMGC_CDK_CDC2_CDK1_ST	Q04637	EIF4G1	P06493	CDK1	S314	A321V	321	Missense	distal	7	no	3.471	3.505	EPSD	GDSC	3.158	Up-regulation
CMGC_CDK_CDC2_CDK1_ST	Q04637	EIF4G1	P06493	CDK1	S314	R312C	312	Missense	proximal	-2	no	3.471	3.421	EPSD	GDSC	3.158	Down-regulation
CMGC_CDK_CDC2_CDK1_ST	P48200	IREB2	P06493	CDK1	T777	Y770H	770	Missense	distal	-7	no	3.293	3.346	EPSD	GDSC;CCLE	3.158	Up-regulation
CMGC_CDK_CDC2_CDK1_ST	P48200	IREB2	P06493	CDK1	T777	F781L	781	Missense	distal	4	no	3.293	3.270	EPSD	GDSC;CCLE	3.158	Down-regulation
CMGC_CDK_CDC2_CDK1_ST	Q15788	NCOA1	P06493	CDK1	S22	T26P	26	Missense	distal	4	no	3.582	3.578	EPSD	GDSC;CCLE	3.158	Down-regulation
CMGC_CDK_CDC2_CDK1_ST	Q14807	KIF22	P06493	CDK1	S427	A420T	420	Missense	distal	-7	no	4.270	4.264	PhosphoSitePlus;EPSD	GDSC	3.158	Down-regulation
CMGC_CDK_CDC2_CDK1_ST	P02545	LMNA	P06493	CDK1	S657	S662I	662	Missense	distal	5	no	3.356	3.520	EPSD	GDSC;CCLE	3.158	Up-regulation
CMGC_CDK_CDC2_CDK1_ST	P02545	LMNA	P06493	CDK1	S657	N660I	660	Missense	distal	3	no	3.356	3.254	EPSD	GDSC;CCLE	3.158	Down-regulation
CMGC_CDK_CDC2_CDK1_ST	Q9UNH5	CDC14A	P06493	CDK1	S453	A458T	458	Missense	distal	5	no	3.145	3.208	PhosphoSitePlus;EPSD	GDSC	3.158	Gain
CMGC_CDK_CDC2_CDK1_ST	P0C1Z6	TFPT	P06493	CDK1	S167	R170K	170	Missense	distal	3	no	3.460	3.442	EPSD	GDSC;CCLE	3.158	Down-regulation
CMGC_CDK_CDC2_CDK1_ST	P0C1Z6	TFPT	P06493	CDK1	S249	P245S	245	Missense	distal	-4	no	3.222	3.272	EPSD	GDSC;CCLE	3.158	Up-regulation
CMGC_CDK_CDC2_CDK1_ST	O43683	BUB1	P06493	CDK1	S459	V462M	462	Missense	distal	3	no	3.196	3.257	EPSD	GDSC;CCLE	3.158	Up-regulation
CMGC_CDK_CDC2_CDK1_ST	O43683	BUB1	P06493	CDK1	S459	P460H	460	Missense	proximal	1	no	3.196	0.512	EPSD	GDSC;CCLE	3.158	Loss
CMGC_CDK_CDC2_CDK1_ST	P54132	BLM	P06493	CDK1	S714	V721A	721	Missense	distal	7	no	3.348	3.314	PhosphoSitePlus;EPSD	GDSC;CCLE	3.158	Down-regulation
CMGC_CDK_CDC2_CDK1_ST	P39748	FEN1	P06493	CDK1	S187	L190V	190	Missense	distal	3	no	3.240	3.323	PhosphoSitePlus	GDSC;CCLE	3.158	Up-regulation
CMGC_CDK_CDC2_CDK1_ST	Q9UGP4	LIMD1	P06493	CDK1	S197	G195R	195	Missense	proximal	-2	no	3.435	3.412	EPSD	GDSC;CCLE	3.158	Down-regulation
CMGC_CDK_CDC2_CDK1_ST	Q9UGP4	LIMD1	P06493	CDK1	T294	V290F	290	Missense	distal	-4	no	3.302	3.277	EPSD	GDSC;CCLE	3.158	Down-regulation
CMGC_CDK_CDC2_CDK1_ST	P10275	AR	P06493	CDK1	S516	E523D	523	Missense	distal	7	no	3.208	3.207	EPSD;PhosphoSitePlus	GDSC	3.158	Down-regulation
CMGC_CDK_CDC2_CDK1_ST	Q9NRI5	DISC1	P06493	CDK1	S241	E236G	236	Missense	distal	-5	no	3.205	3.278	EPSD	GDSC;CCLE	3.158	Up-regulation
CMGC_CDK_CDC2_CDK1_ST	P27816	MAP4	P06493	CDK1	S14	A7S	7	Missense	distal	-7	no	3.613	3.586	EPSD	GDSC;CCLE	3.158	Down-regulation
CMGC_CDK_CDC2_CDK1_ST	P27816	MAP4	P06493	CDK1	S384	P385L	385	Missense	proximal	1	no	3.415	-0.271	EPSD	GDSC;CCLE	3.158	Loss
CMGC_CDK_CDC2_CDK1_ST	P27816	MAP4	P06493	CDK1	T571	T571P	571	Missense	central	0	yes	3.328	0.000	EPSD	GDSC	3.158	Loss
CMGC_CDK_CDC2_CDK1_ST	Q8IX90	SKA3	P06493	CDK1	T358	S351F	351	Missense	distal	-7	no	3.753	3.607	PhosphoSitePlus;EPSD	GDSC;CCLE	3.158	Down-regulation
CMGC_CDK_CDC2_CDK1_ST	P42898	MTHFR	P06493	CDK1	T34	D38E	38	Missense	distal	4	no	3.355	3.356	PhosphoSitePlus	GDSC;CCLE	3.158	Up-regulation
CMGC_CDK_CDC2_CDK1_ST	P24928	POLR2A	P06493	CDK1	T368	I367T	367	Missense	proximal	-1	no	3.522	3.297	EPSD	GDSC;CCLE	3.158	Down-regulation
CMGC_CDK_CDC2_CDK1_ST	P24928	POLR2A	P06493	CDK1	S1962	I1961V	1961	Missense	proximal	-1	no	3.683	3.631	EPSD	GDSC;CCLE	3.158	Down-regulation
CMGC_CDK_CDC2_CDK1_ST	Q8N122	RPTOR	P06493	CDK1	S711	R716I	716	Missense	distal	5	no	3.133	3.306	EPSD	GDSC;CCLE	3.158	Gain
CMGC_CDK_CDC2_CDK1_ST	Q8N122	RPTOR	P06493	CDK1	S877	S881P	881	Missense	distal	4	no	3.669	3.673	EPSD	GDSC;CCLE	3.158	Up-regulation
CMGC_CDK_CDC2_CDK1_ST	Q14C86	GAPVD1	P06493	CDK1	S66	C71W	71	Missense	distal	5	no	3.873	3.878	EPSD	GDSC;CCLE	3.158	Up-regulation
CMGC_CDK_CDC2_CDK1_ST	P06748	NPM1	P06493	CDK1	T219	P220L	220	Missense	proximal	1	no	3.192	-0.494	EPSD;PhosphoSitePlus	GDSC;CCLE	3.158	Loss
CMGC_CDK_CDC2_CDK1_ST	Q9BTA9	WAC	P06493	CDK1	S64	S62T	62	Missense	proximal	-2	no	3.405	3.366	EPSD	GDSC;CCLE	3.158	Down-regulation
CMGC_CDK_CDC2_CDK1_ST	Q9BTA9	WAC	P06493	CDK1	T293	L288*	288	Missense	distal	-5	no	3.056	3.173	EPSD	GDSC	3.158	Gain
CMGC_CDK_CDC2_CDK1_ST	Q8NCD3	HJURP	P06493	CDK1	T380	V379L	379	Missense	proximal	-1	no	3.423	3.479	EPSD	GDSC;CCLE	3.158	Up-regulation
CMGC_CDK_CDC2_CDK1_ST	Q8NCD3	HJURP	P06493	CDK1	S412	V414L	414	Missense	proximal	2	no	3.583	3.589	EPSD;PhosphoSitePlus	GDSC;CCLE	3.158	Up-regulation
CMGC_CDK_CDC2_CDK1_ST	P46013	MKI67	P06493	CDK1	T1176	D1183E	1183	Missense	distal	7	no	4.400	4.401	EPSD	GDSC	3.158	Up-regulation
CMGC_CDK_CDC2_CDK1_ST	P46013	MKI67	P06493	CDK1	T1176	A1180S	1180	Missense	distal	4	no	4.400	4.340	EPSD	GDSC	3.158	Down-regulation
CMGC_CDK_CDC2_CDK1_ST	P46013	MKI67	P06493	CDK1	T1540	A1534T	1534	Missense	distal	-6	no	4.189	4.190	EPSD	GDSC;CCLE	3.158	Up-regulation
CMGC_CDK_CDC2_CDK1_ST	P46013	MKI67	P06493	CDK1	T1540	H1539Q	1539	Missense	proximal	-1	no	4.189	4.154	EPSD	GDSC;CCLE	3.158	Down-regulation
CMGC_CDK_CDC2_CDK1_ST	P46013	MKI67	P06493	CDK1	S1618	Q1619P	1619	Missense	proximal	1	no	1.125	3.548	EPSD	GDSC;CCLE	3.158	Gain
CMGC_CDK_CDC2_CDK1_ST	P46013	MKI67	P06493	CDK1	S2223	S2223Y	2223	Missense	central	0	yes	3.306	0.000	EPSD	GDSC;CCLE	3.158	Loss
CMGC_CDK_CDC2_CDK1_ST	P46013	MKI67	P06493	CDK1	T2380	R2379*	2379	Missense	proximal	-1	no	2.855	3.277	EPSD	GDSC	3.158	Gain
CMGC_CDK_CDC2_CDK1_ST	Q14005	IL16	P06493	CDK1	S1023	K1019N	1019	Missense	distal	-4	no	3.239	3.280	EPSD	GDSC;CCLE	3.158	Up-regulation
CMGC_CDK_CDC2_CDK1_ST	O94901	SUN1	P06493	CDK1	S48	V45A	45	Missense	distal	-3	no	3.410	3.472	EPSD;PhosphoSitePlus	GDSC	3.158	Up-regulation
CMGC_CDK_CDC2_CDK1_ST	P00533	EGFR	P06493	CDK1	S752	A750E	750	Missense	proximal	-2	no	3.109	3.267	EPSD	GDSC	3.158	Gain
CMGC_CDK_CDC2_CDK1_ST	Q99708	RBBP8	P06493	CDK1	S10	G9E	9	Missense	proximal	-1	no	3.676	3.549	EPSD	GDSC;CCLE	3.158	Down-regulation
CMGC_CDK_CDC2_CDK1_ST	Q99708	RBBP8	P06493	CDK1	S568	P569S	569	Missense	proximal	1	no	3.390	0.205	EPSD	GDSC;CCLE	3.158	Loss
CMGC_CDK_CDC2_CDK1_ST	O00429	DNM1L	P06493	CDK1	S136	P137T	137	Missense	proximal	1	no	3.614	1.181	EPSD	GDSC	3.158	Loss
CMGC_CDK_CDC2_CDK1_ST	O00429	DNM1L	P06493	CDK1	S136	V139I	139	Missense	distal	3	no	3.614	3.617	EPSD	GDSC	3.158	Up-regulation
CMGC_CDK_CDC2_CDK1_ST	O00429	DNM1L	P06493	CDK1	S548	P547L	547	Missense	proximal	-1	no	3.121	3.272	EPSD	GDSC	3.158	Gain
CMGC_CDK_CDC2_CDK1_ST	O00512	BCL9	P06493	CDK1	S62	P61T	61	Missense	proximal	-1	no	3.412	3.334	EPSD	GDSC;CCLE	3.158	Down-regulation
CMGC_CDK_CDC2_CDK1_ST	O00512	BCL9	P06493	CDK1	S62	S62P	62	Missense	central	0	yes	3.412	0.000	EPSD	GDSC;CCLE	3.158	Loss
CMGC_CDK_CDC2_CDK1_ST	O00512	BCL9	P06493	CDK1	S441	P439L	439	Missense	proximal	-2	no	3.178	3.352	EPSD	GDSC;CCLE	3.158	Up-regulation
CMGC_CDK_CDC2_CDK1_ST	O00311	CDC7	P06493	CDK1	S16	R21Q	21	Missense	distal	5	no	3.390	3.413	EPSD	GDSC;CCLE	3.158	Up-regulation
CMGC_CDK_CDC2_CDK1_ST	P31350	RRM2	P06493	CDK1	S20	L27F	27	Missense	distal	7	no	3.329	3.321	EPSD;PhosphoSitePlus	GDSC	3.158	Down-regulation
CMGC_CDK_CDC2_CDK1_ST	P31350	RRM2	P06493	CDK1	T33	L27F	27	Missense	distal	-6	no	3.423	3.418	PhosphoSitePlus;EPSD	GDSC	3.158	Down-regulation
CMGC_CDK_CDC2_CDK1_ST	Q8IZP0	ABI1	P06493	CDK1	T196	R194Q	194	Missense	proximal	-2	no	3.597	3.543	EPSD	GDSC;CCLE	3.158	Down-regulation
CMGC_CDK_CDC2_CDK1_ST	P16949	STMN1	P06493	CDK1	S38	P36T	36	Missense	proximal	-2	no	3.443	3.531	EPSD;PhosphoSitePlus	GDSC;CCLE	3.158	Up-regulation
CMGC_CDK_CDC2_CDK1_ST	P11387	TOP1	P06493	CDK1	S394	P397A	397	Missense	distal	3	no	3.284	3.387	PhosphoSitePlus;EPSD	GDSC;CCLE	3.158	Up-regulation
CMGC_CDK_CDC2_CDK1_ST	P06400	RB1	P06493	CDK1	S780	R787*	787	Missense	distal	7	no	3.910	3.949	EPSD	GDSC	3.158	Up-regulation
CMGC_CDK_CDC2_CDK1_ST	P06400	RB1	P06493	CDK1	S807	G801*	801	Missense	distal	-6	no	3.756	3.783	EPSD;PhosphoSitePlus	GDSC	3.158	Up-regulation
CMGC_CDK_CDC2_CDK1_ST	Q69YH5	CDCA2	P06493	CDK1	S98	A95T	95	Missense	distal	-3	no	3.244	3.206	EPSD	GDSC;CCLE	3.158	Down-regulation
CMGC_CDK_CDC2_CDK1_ST	Q69YH5	CDCA2	P06493	CDK1	S98	N102S	102	Missense	distal	4	no	3.244	3.262	EPSD	GDSC;CCLE	3.158	Up-regulation
CMGC_CDK_CDC2_CDK1_ST	Q69YH5	CDCA2	P06493	CDK1	T412	R415C	415	Missense	distal	3	no	3.839	3.720	PhosphoSitePlus	GDSC;CCLE	3.158	Down-regulation
CMGC_CDK_CDC2_CDK1_ST	Q69YH5	CDCA2	P06493	CDK1	T412	N411D	411	Missense	proximal	-1	no	3.839	3.834	PhosphoSitePlus	GDSC	3.158	Down-regulation
CMGC_CDK_CDC2_CDK1_ST	P04179	SOD2	P06493	CDK1	S106	E112G	112	Missense	distal	6	no	3.273	3.241	PhosphoSitePlus	GDSC	3.158	Down-regulation
CMGC_CDK_CDC2_CDK1_ST	Q6PGQ7	BORA	P06493	CDK1	S27	S27G	27	Missense	central	0	yes	3.306	0.000	EPSD	GDSC;CCLE	3.158	Loss
CMGC_CDK_CDC2_CDK1_ST	Q6PGQ7	BORA	P06493	CDK1	T52	F45V	45	Missense	distal	-7	no	3.142	3.164	EPSD	GDSC;CCLE	3.158	Gain
CMGC_CDK_CDC2_CDK1_ST	Q6PGQ7	BORA	P06493	CDK1	S183	L187I	187	Missense	distal	4	no	3.308	3.332	EPSD	GDSC	3.158	Up-regulation
CMGC_CDK_CDC2_CDK1_ST	Q6PGQ7	BORA	P06493	CDK1	S183	E178K	178	Missense	distal	-5	no	3.308	3.339	EPSD	GDSC	3.158	Up-regulation
CMGC_CDK_CDC2_CDK1_ST	Q6PGQ7	BORA	P06493	CDK1	S268	G264*	264	Missense	distal	-4	no	3.196	3.048	EPSD	GDSC	3.158	Loss
CMGC_CDK_CDC2_CDK1_ST	Q13535	ATR	P06493	CDK1	S428	R432H	432	Missense	distal	4	no	3.175	3.134	PhosphoSitePlus	GDSC;CCLE	3.158	Loss
CMGC_CDK_CDC2_CDK1_ST	Q13535	ATR	P06493	CDK1	S1693	V1689L	1689	Missense	distal	-4	no	3.202	3.129	EPSD	GDSC;CCLE	3.158	Loss
CMGC_CDK_CDC2_CDK1_ST	Q13535	ATR	P06493	CDK1	S1693	S1693G	1693	Missense	central	0	yes	3.202	0.000	EPSD	GDSC;CCLE	3.158	Loss
CMGC_CDK_CDC2_CDK1_ST	Q9ULW0	TPX2	P06493	CDK1	T338	V331A	331	Missense	distal	-7	no	3.029	3.181	EPSD	GDSC;CCLE	3.158	Gain
CMGC_CDK_CDC2_CDK1_ST	P38398	BRCA1	P06493	CDK1	S896	Q895*	895	Missense	proximal	-1	no	2.849	3.283	EPSD	GDSC	3.158	Gain
CMGC_CDK_CDC2_CDK1_ST	O95835	LATS1	P06493	CDK1	T255	P258S	258	Missense	distal	3	no	3.118	3.168	EPSD	GDSC;CCLE	3.158	Gain
CMGC_CDK_CDC2_CDK1_ST	O95835	LATS1	P06493	CDK1	S635	Q637*	637	Missense	proximal	2	no	3.266	3.312	EPSD	GDSC	3.158	Up-regulation
CMGC_CDK_CDC2_CDK1_ST	Q2M2I8	AAK1	P06493	CDK1	T389	P390T	390	Missense	proximal	1	no	3.236	0.803	PhosphoSitePlus	GDSC;CCLE	3.158	Loss
CMGC_CDK_CDC2_CDK1_ST	Q2M2I8	AAK1	P06493	CDK1	T620	S624F	624	Missense	distal	4	no	3.179	3.083	EPSD	GDSC;CCLE	3.158	Loss
CMGC_CDK_CDC2_CDK1_ST	Q14203	DCTN1	P06493	CDK1	S212	E218G	218	Missense	distal	6	no	3.207	3.175	PhosphoSitePlus	GDSC;CCLE	3.158	Down-regulation
CMGC_CDK_CDC2_CDK1_ST	Q14203	DCTN1	P06493	CDK1	S1180	M1186I	1186	Missense	distal	6	no	3.167	3.139	EPSD	GDSC	3.158	Loss
CMGC_CDK_CDC2_CDK1_ST	P36956	SREBF1	P06493	CDK1	T105	P99T	99	Missense	distal	-6	no	3.336	3.334	EPSD	GDSC	3.158	Down-regulation
CMGC_CDK_CDC2_CDK1_ST	P36956	SREBF1	P06493	CDK1	S386	L387P	387	Missense	proximal	1	no	-0.470	3.217	EPSD	GDSC	3.158	Gain
CMGC_CDK_CDC2_CDK1_ST	Q13009	TIAM1	P06493	CDK1	T61	P62L	62	Missense	proximal	1	no	3.365	-0.322	EPSD	GDSC;CCLE	3.158	Loss
CMGC_CDK_CDC2_CDK1_ST	Q13009	TIAM1	P06493	CDK1	S1466	S1465R	1465	Missense	proximal	-1	no	3.213	3.275	PhosphoSitePlus	GDSC;CCLE	3.158	Up-regulation
CMGC_CDK_CDC2_CDK1_ST	Q13009	TIAM1	P06493	CDK1	S1466	P1467T	1467	Missense	proximal	1	no	3.213	0.780	PhosphoSitePlus	GDSC;CCLE	3.158	Loss
CMGC_CDK_CDC2_CDK1_ST	Q13009	TIAM1	P06493	CDK1	S1466	S1463F	1463	Missense	distal	-3	no	3.213	3.186	PhosphoSitePlus	GDSC	3.158	Down-regulation
CMGC_CDK_CDC2_CDK1_ST	Q13009	TIAM1	P06493	CDK1	S1466	E1470*	1470	Missense	distal	4	no	3.213	3.027	PhosphoSitePlus	GDSC	3.158	Loss
CMGC_CDK_CDC2_CDK1_ST	Q9Y3Z3	SAMHD1	P06493	CDK1	T21	P26L	26	Missense	distal	5	no	3.093	3.278	EPSD	GDSC	3.158	Gain
CMGC_CDK_CDC2_CDK1_ST	Q9Y3Z3	SAMHD1	P06493	CDK1	T25	P26L	26	Missense	proximal	1	no	3.616	-0.071	EPSD	GDSC	3.158	Loss
CMGC_CDK_CDC2_CDK1_ST	Q9Y3Z3	SAMHD1	P06493	CDK1	S33	P26L	26	Missense	distal	-7	no	3.315	3.155	EPSD	GDSC	3.158	Loss
CMGC_CDK_CDC2_CDK1_ST	Q9Y3Z3	SAMHD1	P06493	CDK1	S278	L276P	276	Missense	proximal	-2	no	3.268	3.094	EPSD	GDSC	3.158	Loss
CMGC_CDK_CDC2_CDK1_ST	O00267	SUPT5H	P06493	CDK1	S686	G682D	682	Missense	distal	-4	no	3.414	3.493	EPSD	GDSC;CCLE	3.158	Up-regulation
CMGC_CDK_CDC2_CDK1_ST	Q9UKX7	NUP50	P06493	CDK1	S296	P297L	297	Missense	proximal	1	no	3.262	-0.424	EPSD	GDSC;CCLE	3.158	Loss
CMGC_CDK_CDC2_CDK1_ST	P54578	USP14	P06493	CDK1	T235	A234G	234	Missense	proximal	-1	no	3.341	3.615	PhosphoSitePlus	GDSC	3.158	Up-regulation
CMGC_CDK_CDC2_CDK1_ST	P54578	USP14	P06493	CDK1	T235	S229L	229	Missense	distal	-6	no	3.341	3.369	PhosphoSitePlus	GDSC;CCLE	3.158	Up-regulation
CMGC_CDK_CDC2_CDK1_ST	P54578	USP14	P06493	CDK1	S394	K392N	392	Missense	proximal	-2	no	3.421	3.383	EPSD	GDSC;CCLE	3.158	Down-regulation
CMGC_CDK_CDC2_CDK1_ST	P23769	GATA2	P06493	CDK1	T303	G310S	310	Missense	distal	7	no	3.244	3.217	EPSD	GDSC	3.158	Down-regulation
CMGC_CDK_CDC2_CDK1_ST	Q96C19	EFHD2	P06493	CDK1	S74	P72S	72	Missense	proximal	-2	no	3.259	3.385	PhosphoSitePlus	GDSC;CCLE	3.158	Up-regulation
CMGC_CDK_CDC2_CDK1_ST	Q13501	SQSTM1	P06493	CDK1	S170	L166I	166	Missense	distal	-4	no	3.109	3.160	EPSD	GDSC;CCLE	3.158	Gain
CMGC_CDK_CDC2_CDK1_ST	Q8IX03	WWC1	P06493	CDK1	S358	E353Q	353	Missense	distal	-5	no	3.522	3.494	EPSD	GDSC;CCLE	3.158	Down-regulation
CMGC_CDK_CDC2_CDK1_ST	Q8IX03	WWC1	P06493	CDK1	T912	K906E	906	Missense	distal	-6	no	3.247	3.245	EPSD	GDSC;CCLE	3.158	Down-regulation
CMGC_CDK_CDC2_CDK1_ST	Q8IX03	WWC1	P06493	CDK1	T912	L919F	919	Missense	distal	7	no	3.247	3.239	EPSD	GDSC;CCLE	3.158	Down-regulation
CMGC_CDK_CDC2_CDK1_ST	Q14244	MAP7	P06493	CDK1	S315	A313V	313	Missense	proximal	-2	no	3.416	3.581	EPSD	GDSC;CCLE	3.158	Up-regulation
CMGC_CDK_CDC2_CDK1_ST	P35611	ADD1	P06493	CDK1	S12	A7V	7	Missense	distal	-5	no	3.066	3.206	PhosphoSitePlus;EPSD	GDSC	3.158	Gain
CMGC_CDK_CDC2_CDK1_ST	Q96T23	RSF1	P06493	CDK1	S570	S570F	570	Missense	central	0	yes	3.340	0.000	EPSD	GDSC;CCLE	3.158	Loss
CMGC_CDK_CDC2_CDK1_ST	Q96T23	RSF1	P06493	CDK1	S622	S617*	617	Missense	distal	-5	no	3.296	3.557	EPSD	GDSC	3.158	Up-regulation
CMGC_CDK_CDC2_CDK1_ST	Q96T23	RSF1	P06493	CDK1	S629	P630S	630	Missense	proximal	1	no	3.551	0.367	EPSD	GDSC;CCLE	3.158	Loss
CMGC_CDK_CDC2_CDK1_ST	Q96T23	RSF1	P06493	CDK1	T812	A813P	813	Missense	proximal	1	no	2.427	3.316	EPSD	GDSC;CCLE	3.158	Gain
CMGC_CDK_CDC2_CDK1_ST	P24864	CCNE1	P06493	CDK1	S103	S100C	100	Missense	distal	-3	no	3.241	3.226	EPSD	GDSC;CCLE	3.158	Down-regulation
CMGC_CDK_CDC2_CDK1_ST	P24864	CCNE1	P06493	CDK1	T395	L394P	394	Missense	proximal	-1	no	3.467	3.317	EPSD	GDSC	3.158	Down-regulation
CMGC_CDK_CDC2_CDK1_ST	O43521	BCL2L11	P06493	CDK1	S59	G62V	62	Missense	distal	3	no	3.382	3.404	EPSD	GDSC;CCLE	3.158	Up-regulation
CMGC_CDK_CDC2_CDK1_ST	O43521	BCL2L11	P06493	CDK1	S69	G62V	62	Missense	distal	-7	no	3.155	3.189	EPSD	GDSC;CCLE	3.158	Gain
CMGC_CDK_CDC2_CDK1_ST	Q06413	MEF2C	P06493	CDK1	S183	R189*	189	Missense	distal	6	no	3.587	3.468	EPSD	GDSC	3.158	Down-regulation
CMGC_CDK_CDC2_CDK1_ST	Q06413	MEF2C	P06493	CDK1	S222	R220*	220	Missense	proximal	-2	no	3.013	3.177	EPSD	GDSC	3.158	Gain
CMGC_CDK_CDC2_CDK1_ST	O43663	PRC1	P06493	CDK1	S513	V515M	515	Missense	proximal	2	no	3.253	3.245	EPSD	GDSC;CCLE	3.158	Down-regulation
CMGC_CDK_CDC2_CDK1_ST	O43663	PRC1	P06493	CDK1	T536	R538C	538	Missense	proximal	2	no	3.465	3.472	EPSD	GDSC;CCLE	3.158	Up-regulation
CMGC_CDK_CDC2_CDK1_ST	O43663	PRC1	P06493	CDK1	T536	S532*	532	Missense	distal	-4	no	3.465	3.180	EPSD	GDSC	3.158	Down-regulation
CMGC_CDK_CDC2_CDK1_ST	P33993	MCM7	P06493	CDK1	S365	K370N	370	Missense	distal	5	no	3.344	3.352	EPSD	GDSC;CCLE	3.158	Up-regulation
CMGC_CDK_CDC2_CDK1_ST	O75170	PPP6R2	P06493	CDK1	T430	P433L	433	Missense	distal	3	no	3.440	3.307	EPSD	GDSC;CCLE	3.158	Down-regulation
CMGC_CDK_CDC2_CDK1_ST	O75170	PPP6R2	P06493	CDK1	T430	A435T	435	Missense	distal	5	no	3.440	3.503	EPSD	GDSC	3.158	Up-regulation
CMGC_CDK_CDC2_CDK1_ST	Q2NKX8	ERCC6L	P06493	CDK1	S755	Q753R	753	Missense	proximal	-2	no	3.155	3.209	EPSD	GDSC	3.158	Gain
CMGC_CDK_CDC2_CDK1_ST	P49821	NDUFV1	P06493	CDK1	T383	C382W	382	Missense	proximal	-1	no	3.629	3.646	PhosphoSitePlus	GDSC;CCLE	3.158	Up-regulation
CMGC_CDK_CDC2_CDK1_ST	O00399	DCTN6	P06493	CDK1	T71	A65V	65	Missense	distal	-6	no	3.921	3.943	EPSD	GDSC	3.158	Up-regulation
CMGC_CDK_CDC2_CDK1_ST	Q8TF76	HASPIN	P06493	CDK1	S179	P180L	180	Missense	proximal	1	no	3.187	-0.500	EPSD	GDSC	3.158	Loss
CMGC_CDK_CDC2_CDK1_ST	Q8WX93	PALLD	P06493	CDK1	T100	T100K	100	Missense	central	0	yes	3.428	0.000	EPSD	GDSC;CCLE	3.158	Loss
CMGC_CDK_CDC2_CDK1_ST	Q8WX93	PALLD	P06493	CDK1	T147	E141K	141	Missense	distal	-6	no	3.491	3.492	EPSD	GDSC;CCLE	3.158	Up-regulation
CMGC_CDK_CDC2_CDK1_ST	Q8WX93	PALLD	P06493	CDK1	S484	D486Y	486	Missense	proximal	2	no	3.166	3.172	EPSD	GDSC;CCLE	3.158	Up-regulation
CMGC_CDK_CDC2_CDK1_ST	O60285	NUAK1	P06493	CDK1	S445	A448V	448	Missense	distal	3	no	3.188	3.035	PhosphoSitePlus	GDSC	3.158	Loss
CMGC_CDK_CDC2_CDK1_ST	O60285	NUAK1	P06493	CDK1	S455	A448V	448	Missense	distal	-7	no	3.500	3.348	EPSD	GDSC	3.158	Down-regulation
CMGC_CDK_CDC2_CDK1_ST	P00338	LDHA	P06493	CDK1	S128	I135M	135	Missense	distal	7	no	3.205	3.190	EPSD	GDSC;CCLE	3.158	Down-regulation
CMGC_CDK_CDC2_CDK1_ST	P04637	TP53	P06493	CDK1	S33	Q38*	38	Missense	distal	5	no	3.447	3.785	EPSD	GDSC	3.158	Up-regulation
CMGC_CDK_CDC2_CDK1_ST	P04637	TP53	P06493	CDK1	T81	A74S	74	Missense	distal	-7	no	3.467	3.440	EPSD	GDSC;CCLE	3.158	Down-regulation
CMGC_CDK_CDC2_CDK1_ST	P30101	PDIA3	P06493	CDK1	S456	I453T	453	Missense	distal	-3	no	3.467	3.512	PhosphoSitePlus	GDSC;CCLE	3.158	Up-regulation
CMGC_CDK_CDC2_CDK1_ST	Q8NEB9	PIK3C3	P06493	CDK1	T159	T166S	166	Missense	distal	7	no	3.411	3.408	PhosphoSitePlus	GDSC;CCLE	3.158	Down-regulation
CMGC_CDK_CDC2_CDK1_ST	Q8TD19	NEK9	P06493	CDK1	S829	A834V	834	Missense	distal	5	no	3.256	3.463	EPSD	GDSC;CCLE	3.158	Up-regulation
CMGC_CDK_CDC2_CDK1_ST	Q02952	AKAP12	P06493	CDK1	S483	L482V	482	Missense	proximal	-1	no	3.493	3.437	EPSD	GDSC	3.158	Down-regulation
CMGC_CDK_CDC2_CDK1_ST	Q02952	AKAP12	P06493	CDK1	T767	T767M	767	Missense	central	0	yes	3.239	0.000	PhosphoSitePlus	GDSC	3.158	Loss
CMGC_CDK_CDC2_CDK1_ST	Q02952	AKAP12	P06493	CDK1	T767	K773R	773	Missense	distal	6	no	3.239	3.264	PhosphoSitePlus	GDSC	3.158	Up-regulation
AGC_PKG_PRKG1_ST	Q13976	PRKG1	Q13976-2	PRKG1	S27	Q34E	34	Missense	distal	7	no	10.846	10.762	EPSD	GDSC	7.092	Down-regulation
AGC_PKG_PRKG1_ST	Q13153	PAK1	Q13976-2	PRKG1	S511	D505G	505	Missense	distal	-6	no	10.380	10.654	EPSD	GDSC;CCLE	7.092	Up-regulation
AGC_PKG_PRKG1_ST	Q14847	LASP1	Q13976-2	PRKG1	S61	A66V	66	Missense	distal	5	no	7.442	7.392	EPSD	GDSC	7.092	Down-regulation
STE_STE20_PAKB_PAK4_ST	O43623	SNAI2	O96013	PAK4	S158	Q154*	154	Missense	distal	-4	no	19.917	19.068	PhosphoSitePlus	GDSC	14.946	Down-regulation
STE_STE20_PAKB_PAK4_ST	O96013	PAK4	O96013	PAK4	S217	R218Q	218	Missense	proximal	1	no	15.691	15.264	EPSD	GDSC	14.946	Down-regulation
STE_STE20_PAKB_PAK4_ST	O96013	PAK4	O96013	PAK4	S267	G260A	260	Missense	distal	-7	no	14.672	15.673	EPSD	GDSC;CCLE	14.946	Gain
STE_STE20_PAKB_PAK4_ST	P35222	CTNNB1	O96013	PAK4	S552	R549H	549	Missense	distal	-3	no	19.614	15.608	EPSD	GDSC;CCLE	14.946	Down-regulation
STE_STE20_PAKB_PAK4_ST	P35222	CTNNB1	O96013	PAK4	S675	Y670*	670	Missense	distal	-5	no	29.056	28.370	PhosphoSitePlus	GDSC	14.946	Down-regulation
STE_STE20_PAKB_PAK4_ST	P49023	PXN	O96013	PAK4	S90	V87E	87	Missense	distal	-3	no	14.003	16.099	EPSD	GDSC	14.946	Gain
STE_STE20_PAKB_PAK4_ST	P49023	PXN	O96013	PAK4	S126	P129L	129	Missense	distal	3	no	17.058	17.602	EPSD	GDSC	14.946	Up-regulation
STE_STE20_PAKB_PAK4_ST	P49023	PXN	O96013	PAK4	S320	S321N	321	Missense	proximal	1	no	15.904	16.716	EPSD	GDSC;CCLE	14.946	Up-regulation
STE_STE20_PAKB_PAK4_ST	Q92974	ARHGEF2	O96013	PAK4	S142	R141H	141	Missense	proximal	-1	no	17.668	15.289	EPSD	GDSC	14.946	Down-regulation
STE_STE20_PAKB_PAK4_ST	Q92974	ARHGEF2	O96013	PAK4	S143	R141H	141	Missense	proximal	-2	no	23.198	21.908	EPSD	GDSC	14.946	Down-regulation
STE_STE20_PAKB_PAK4_ST	P04637	TP53	O96013	PAK4	S183	S183*	183	Missense	central	0	yes	14.982	0.000	EPSD	GDSC	14.946	Loss
STE_STE20_PAKB_PAK4_ST	P04637	TP53	O96013	PAK4	S183	E180*	180	Missense	distal	-3	no	14.982	13.127	EPSD	GDSC	14.946	Loss
STE_STE20_PAKB_PAK4_ST	P04637	TP53	O96013	PAK4	S215	R213*	213	Missense	proximal	-2	no	24.434	17.819	PhosphoSitePlus	GDSC	14.946	Down-regulation
STE_STE20_PAKB_PAK4_ST	P04637	TP53	O96013	PAK4	S215	R209*	209	Missense	distal	-6	no	24.434	24.065	PhosphoSitePlus	GDSC	14.946	Down-regulation
STE_STE20_PAKB_PAK4_ST	P04637	TP53	O96013	PAK4	S366	G360V	360	Missense	distal	-6	no	16.494	16.454	EPSD	GDSC;CCLE	14.946	Down-regulation
STE_STE20_PAKB_PAK4_ST	P53667	LIMK1	O96013	PAK4	S430	W434*	434	Missense	distal	4	no	17.595	17.633	EPSD	GDSC	14.946	Up-regulation
STE_STE20_PAKB_PAK4_ST	P53667	LIMK1	O96013	PAK4	T508	R506C	506	Missense	proximal	-2	no	26.601	20.814	PhosphoSitePlus	GDSC;CCLE	14.946	Down-regulation
STE_STE20_PAKB_PAK4_ST	P03372	ESR1	O96013	PAK4	S167	G160S	160	Missense	distal	-7	no	19.706	20.067	EPSD	GDSC	14.946	Up-regulation
STE_STE20_PAKB_PAK4_ST	P03372	ESR1	O96013	PAK4	S167	R164I	164	Missense	distal	-3	no	19.706	14.852	EPSD	GDSC;CCLE	14.946	Loss
STE_STE20_PAKB_PAK4_ST	P03372	ESR1	O96013	PAK4	S236	R241L	241	Missense	distal	5	no	17.263	16.887	EPSD	GDSC;CCLE	14.946	Down-regulation
STE_STE20_PAKB_PAK4_ST	P03372	ESR1	O96013	PAK4	S305	K299N	299	Missense	distal	-6	no	28.139	27.896	PhosphoSitePlus	GDSC;CCLE	14.946	Down-regulation
STE_STE20_PAKB_PAK4_ST	P03372	ESR1	O96013	PAK4	S305	I298V	298	Missense	distal	-7	no	28.139	27.537	PhosphoSitePlus	GDSC	14.946	Down-regulation
STE_STE20_PAKB_PAK4_ST	Q93045	STMN2	O96013	PAK4	S16	L18V	18	Missense	proximal	2	no	15.340	16.909	EPSD	GDSC;CCLE	14.946	Up-regulation
CAMK_RAD53_CHEK2_ST	P04637	TP53	O96017	CHEK2	S37	Q38*	38	Missense	proximal	1	no	10.326	5.446	EPSD;PhosphoSitePlus	GDSC	8.561	Loss
CAMK_RAD53_CHEK2_ST	P04637	TP53	O96017	CHEK2	T81	A74S	74	Missense	distal	-7	no	9.581	10.646	EPSD	GDSC;CCLE	8.561	Up-regulation
CAMK_RAD53_CHEK2_ST	P04637	TP53	O96017	CHEK2	S99	K101*	101	Missense	proximal	2	no	8.743	8.193	EPSD	GDSC	8.561	Loss
CAMK_RAD53_CHEK2_ST	P04637	TP53	O96017	CHEK2	S99	Q100*	100	Missense	proximal	1	no	8.743	3.863	EPSD	GDSC	8.561	Loss
CAMK_RAD53_CHEK2_ST	P04637	TP53	O96017	CHEK2	S99	S94*	94	Missense	distal	-5	no	8.743	7.313	EPSD	GDSC	8.561	Loss
CAMK_RAD53_CHEK2_ST	P04637	TP53	O96017	CHEK2	S269	E271*	271	Missense	proximal	2	no	12.111	11.646	EPSD	GDSC	8.561	Down-regulation
CAMK_RAD53_CHEK2_ST	P04637	TP53	O96017	CHEK2	S366	G360V	360	Missense	distal	-6	no	12.323	12.162	PhosphoSitePlus;EPSD	GDSC;CCLE	8.561	Down-regulation
CAMK_RAD53_CHEK2_ST	O96017	CHEK2	O96017	CHEK2	T68	S73F	73	Missense	distal	5	no	9.703	9.315	EPSD;PhosphoSitePlus	GDSC;CCLE	8.561	Down-regulation
CAMK_RAD53_CHEK2_ST	P33981	TTK	O96017	CHEK2	S440	P438S	438	Missense	proximal	-2	no	10.146	10.383	EPSD	GDSC;CCLE	8.561	Up-regulation
CAMK_RAD53_CHEK2_ST	Q9NY61	AATF	O96017	CHEK2	S61	L65W	65	Missense	distal	4	no	9.536	10.401	EPSD	GDSC;CCLE	8.561	Up-regulation
CAMK_RAD53_CHEK2_ST	Q9NY61	AATF	O96017	CHEK2	T366	R363M	363	Missense	distal	-3	no	8.634	1.433	EPSD	GDSC;CCLE	8.561	Loss
CAMK_RAD53_CHEK2_ST	Q9NY61	AATF	O96017	CHEK2	T366	T366A	366	Missense	central	0	yes	8.634	0.000	EPSD	GDSC;CCLE	8.561	Loss
CAMK_RAD53_CHEK2_ST	Q9NY61	AATF	O96017	CHEK2	T394	E389Q	389	Missense	distal	-5	no	11.798	12.681	EPSD	GDSC;CCLE	8.561	Up-regulation
CAMK_RAD53_CHEK2_ST	Q08050	FOXM1	O96017	CHEK2	S306	I310T	310	Missense	distal	4	no	8.861	8.334	EPSD	GDSC;CCLE	8.561	Loss
CAMK_RAD53_CHEK2_ST	Q08050	FOXM1	O96017	CHEK2	T319	R316C	316	Missense	distal	-3	no	10.462	-0.460	EPSD	GDSC;CCLE	8.561	Loss
CAMK_RAD53_CHEK2_ST	P18887	XRCC1	O96017	CHEK2	S151	S145G	145	Missense	distal	-6	no	13.054	12.785	EPSD	GDSC;CCLE	8.561	Down-regulation
CAMK_RAD53_CHEK2_ST	P18887	XRCC1	O96017	CHEK2	S184	N183S	183	Missense	proximal	-1	no	9.002	8.516	PhosphoSitePlus;EPSD	GDSC;CCLE	8.561	Loss
CAMK_RAD53_CHEK2_ST	P18887	XRCC1	O96017	CHEK2	T296	R300*	300	Missense	distal	4	no	7.599	8.977	EPSD	GDSC	8.561	Gain
CAMK_RAD53_CHEK2_ST	P18887	XRCC1	O96017	CHEK2	S446	S447L	447	Missense	proximal	1	no	7.490	10.298	EPSD	GDSC;CCLE	8.561	Gain
CAMK_RAD53_CHEK2_ST	P18887	XRCC1	O96017	CHEK2	S447	Q441*	441	Missense	distal	-6	no	10.033	9.265	EPSD	GDSC	8.561	Down-regulation
CAMK_RAD53_CHEK2_ST	P18887	XRCC1	O96017	CHEK2	S447	S447L	447	Missense	central	0	yes	10.033	0.000	EPSD	GDSC;CCLE	8.561	Loss
CAMK_RAD53_CHEK2_ST	P30304	CDC25A	O96017	CHEK2	S76	G75C	75	Missense	proximal	-1	no	12.430	12.275	EPSD	GDSC;CCLE	8.561	Down-regulation
CAMK_RAD53_CHEK2_ST	P30304	CDC25A	O96017	CHEK2	T80	G75C	75	Missense	distal	-5	no	8.924	9.744	EPSD	GDSC;CCLE	8.561	Up-regulation
CAMK_RAD53_CHEK2_ST	P30304	CDC25A	O96017	CHEK2	S124	D130G	130	Missense	distal	6	no	12.958	13.143	PhosphoSitePlus;EPSD	GDSC	8.561	Up-regulation
CAMK_RAD53_CHEK2_ST	P30304	CDC25A	O96017	CHEK2	S124	I131V	131	Missense	distal	7	no	12.958	12.945	PhosphoSitePlus;EPSD	GDSC	8.561	Down-regulation
CAMK_RAD53_CHEK2_ST	P30304	CDC25A	O96017	CHEK2	S126	D130G	130	Missense	distal	4	no	12.035	11.776	EPSD	GDSC	8.561	Down-regulation
CAMK_RAD53_CHEK2_ST	P30304	CDC25A	O96017	CHEK2	S126	I131V	131	Missense	distal	5	no	12.035	12.074	EPSD	GDSC	8.561	Up-regulation
CAMK_RAD53_CHEK2_ST	P30304	CDC25A	O96017	CHEK2	S293	S287N	287	Missense	distal	-6	no	17.004	16.636	EPSD;PhosphoSitePlus	GDSC	8.561	Down-regulation
CAMK_RAD53_CHEK2_ST	Q9UHR4	BAIAP2L1	O96017	CHEK2	S132	S136F	136	Missense	distal	4	no	10.092	11.083	EPSD	GDSC;CCLE	8.561	Up-regulation
CAMK_RAD53_CHEK2_ST	Q9UHR4	BAIAP2L1	O96017	CHEK2	S136	S136F	136	Missense	central	0	yes	11.660	0.000	EPSD	GDSC;CCLE	8.561	Loss
CAMK_RAD53_CHEK2_ST	Q9UHR4	BAIAP2L1	O96017	CHEK2	S331	S325N	325	Missense	distal	-6	no	16.079	15.710	PhosphoSitePlus	GDSC;CCLE	8.561	Down-regulation
CAMK_RAD53_CHEK2_ST	Q9NRM7	LATS2	O96017	CHEK2	S380	G385S	385	Missense	distal	5	no	18.133	18.315	EPSD;PhosphoSitePlus	GDSC	8.561	Up-regulation
CAMK_RAD53_CHEK2_ST	Q9NRM7	LATS2	O96017	CHEK2	S380	T374P	374	Missense	distal	-6	no	18.133	18.211	EPSD;PhosphoSitePlus	GDSC	8.561	Up-regulation
CAMK_RAD53_CHEK2_ST	Q9NRM7	LATS2	O96017	CHEK2	S835	W842L	842	Missense	distal	7	no	14.484	14.453	EPSD	GDSC;CCLE	8.561	Down-regulation
CAMK_RAD53_CHEK2_ST	P29590	PML	O96017	CHEK2	T391	S388T	388	Missense	distal	-3	no	8.629	6.944	EPSD	GDSC;CCLE	8.561	Loss
CAMK_RAD53_CHEK2_ST	P29590	PML	O96017	CHEK2	S547	N543S	543	Missense	distal	-4	no	9.517	10.771	EPSD	GDSC;CCLE	8.561	Up-regulation
CAMK_RAD53_CHEK2_ST	P29590	PML	O96017	CHEK2	S547	V545M	545	Missense	proximal	-2	no	9.517	9.326	EPSD	GDSC;CCLE	8.561	Down-regulation
CAMK_RAD53_CHEK2_ST	P29590	PML	O96017	CHEK2	S723	S723N	723	Missense	central	0	yes	8.814	0.000	EPSD	GDSC;CCLE	8.561	Loss
CAMK_RAD53_CHEK2_ST	P29590	PML	O96017	CHEK2	S804	M806V	806	Missense	proximal	2	no	10.647	10.729	EPSD	GDSC;CCLE	8.561	Up-regulation
CAMK_RAD53_CHEK2_ST	P29590	PML	O96017	CHEK2	S828	S824I	824	Missense	distal	-4	no	14.637	12.705	EPSD	GDSC	8.561	Down-regulation
CAMK_RAD53_CHEK2_ST	P29590	PML	O96017	CHEK2	S828	R825C	825	Missense	distal	-3	no	14.637	3.715	EPSD	GDSC;CCLE	8.561	Loss
CAMK_RAD53_CHEK2_ST	P21127	CDK11B	O96017	CHEK2	S38	R41W	41	Missense	distal	3	no	9.284	10.677	EPSD	GDSC;CCLE	8.561	Up-regulation
CAMK_RAD53_CHEK2_ST	P21127	CDK11B	O96017	CHEK2	S72	Y67C	67	Missense	distal	-5	no	14.163	14.683	EPSD	GDSC;CCLE	8.561	Up-regulation
CAMK_RAD53_CHEK2_ST	P21127	CDK11B	O96017	CHEK2	S72	Y67*	67	Missense	distal	-5	no	14.163	13.106	EPSD	GDSC	8.561	Down-regulation
CAMK_RAD53_CHEK2_ST	P21127	CDK11B	O96017	CHEK2	S113	E107*	107	Missense	distal	-6	no	11.783	11.107	EPSD	GDSC	8.561	Down-regulation
CAMK_RAD53_CHEK2_ST	P21127	CDK11B	O96017	CHEK2	S113	E117V	117	Missense	distal	4	no	11.783	12.209	EPSD	GDSC	8.561	Up-regulation
CAMK_RAD53_CHEK2_ST	P21127	CDK11B	O96017	CHEK2	S115	E117V	117	Missense	proximal	2	no	16.333	16.253	EPSD	GDSC	8.561	Down-regulation
CAMK_RAD53_CHEK2_ST	Q01094	E2F1	O96017	CHEK2	S313	G309E	309	Missense	distal	-4	no	10.615	10.553	EPSD	GDSC;CCLE	8.561	Down-regulation
CAMK_RAD53_CHEK2_ST	Q01094	E2F1	O96017	CHEK2	S352	P357Q	357	Missense	distal	5	no	9.172	9.269	EPSD	GDSC	8.561	Up-regulation
CAMK_RAD53_CHEK2_ST	Q01094	E2F1	O96017	CHEK2	S352	L351V	351	Missense	proximal	-1	no	9.172	9.770	EPSD	GDSC;CCLE	8.561	Up-regulation
CAMK_RAD53_CHEK2_ST	Q01094	E2F1	O96017	CHEK2	S352	S349Y	349	Missense	distal	-3	no	9.172	2.457	EPSD	GDSC;CCLE	8.561	Loss
CAMK_RAD53_CHEK2_ST	Q01094	E2F1	O96017	CHEK2	S364	P357Q	357	Missense	distal	-7	no	16.027	15.194	PhosphoSitePlus	GDSC	8.561	Down-regulation
CAMK_RAD53_CHEK2_ST	P10636	MAPT	O96017	CHEK2	T50	Q49H	49	Missense	proximal	-1	no	8.993	9.227	EPSD	GDSC	8.561	Up-regulation
CAMK_RAD53_CHEK2_ST	P10636	MAPT	O96017	CHEK2	S171	D177V	177	Missense	distal	6	no	11.678	11.772	EPSD	GDSC	8.561	Up-regulation
CAMK_RAD53_CHEK2_ST	P10636	MAPT	O96017	CHEK2	S214	V218G	218	Missense	distal	4	no	11.886	11.838	EPSD	GDSC	8.561	Down-regulation
CAMK_RAD53_CHEK2_ST	P10636	MAPT	O96017	CHEK2	S341	P340L	340	Missense	proximal	-1	no	14.117	14.095	EPSD	GDSC;CCLE	8.561	Down-regulation
CAMK_RAD53_CHEK2_ST	P10636	MAPT	O96017	CHEK2	S341	G339S	339	Missense	proximal	-2	no	14.117	14.535	EPSD	GDSC;CCLE	8.561	Up-regulation
CAMK_RAD53_CHEK2_ST	P10636	MAPT	O96017	CHEK2	S641	V635I	635	Missense	distal	-6	no	10.002	9.884	EPSD	GDSC	8.561	Down-regulation
CAMK_RAD53_CHEK2_ST	P54132	BLM	O96017	CHEK2	S269	E265G	265	Missense	distal	-4	no	11.009	11.070	EPSD	GDSC;CCLE	8.561	Up-regulation
CAMK_RAD53_CHEK2_ST	P54132	BLM	O96017	CHEK2	S314	E307G	307	Missense	distal	-7	no	8.881	9.278	EPSD	GDSC;CCLE	8.561	Up-regulation
CAMK_RAD53_CHEK2_ST	P54132	BLM	O96017	CHEK2	S460	H457R	457	Missense	distal	-3	no	5.428	9.160	EPSD	GDSC;CCLE	8.561	Gain
CAMK_RAD53_CHEK2_ST	P54132	BLM	O96017	CHEK2	S539	E546D	546	Missense	distal	7	no	9.677	9.686	EPSD	GDSC;CCLE	8.561	Up-regulation
CAMK_RAD53_CHEK2_ST	P54132	BLM	O96017	CHEK2	S602	A603V	603	Missense	proximal	1	no	12.179	11.807	EPSD	GDSC;CCLE	8.561	Down-regulation
CAMK_RAD53_CHEK2_ST	P54132	BLM	O96017	CHEK2	S646	S648G	648	Missense	proximal	2	no	13.457	13.392	EPSD	GDSC;CCLE	8.561	Down-regulation
CAMK_RAD53_CHEK2_ST	P54132	BLM	O96017	CHEK2	S646	K653T	653	Missense	distal	7	no	13.457	13.465	EPSD	GDSC	8.561	Up-regulation
CAMK_RAD53_CHEK2_ST	P54132	BLM	O96017	CHEK2	S729	I732F	732	Missense	distal	3	no	9.186	9.183	EPSD	GDSC	8.561	Down-regulation
CAMK_RAD53_CHEK2_ST	P54132	BLM	O96017	CHEK2	S729	D722H	722	Missense	distal	-7	no	9.186	11.133	EPSD	GDSC;CCLE	8.561	Up-regulation
CAMK_RAD53_CHEK2_ST	P54132	BLM	O96017	CHEK2	S1375	S1368A	1368	Missense	distal	-7	no	8.723	7.658	EPSD	GDSC	8.561	Loss
CAMK_RAD53_CHEK2_ST	P38398	BRCA1	O96017	CHEK2	T509	L502*	502	Missense	distal	-7	no	11.278	8.766	EPSD	GDSC	8.561	Down-regulation
CAMK_RAD53_CHEK2_ST	P38398	BRCA1	O96017	CHEK2	S896	Q895*	895	Missense	proximal	-1	no	8.599	9.977	EPSD	GDSC	8.561	Up-regulation
CAMK_RAD53_CHEK2_ST	P38398	BRCA1	O96017	CHEK2	S1239	N1236K	1236	Missense	distal	-3	no	6.626	10.238	EPSD	GDSC	8.561	Gain
CAMK_RAD53_CHEK2_ST	P38398	BRCA1	O96017	CHEK2	S1598	S1596A	1596	Missense	proximal	-2	no	8.549	8.714	EPSD	GDSC	8.561	Gain
CAMK_RAD53_CHEK2_ST	Q13263	TRIM28	O96017	CHEK2	S285	R282C	282	Missense	distal	-3	no	11.409	0.486	EPSD	GDSC;CCLE	8.561	Loss
CAMK_RAD53_CHEK2_ST	Q13263	TRIM28	O96017	CHEK2	T415	G414S	414	Missense	proximal	-1	no	11.020	10.677	EPSD	GDSC;CCLE	8.561	Down-regulation
CAMK_RAD53_CHEK2_ST	Q13263	TRIM28	O96017	CHEK2	T415	T415I	415	Missense	central	0	yes	11.020	0.000	EPSD	GDSC;CCLE	8.561	Loss
CAMK_RAD53_CHEK2_ST	Q13263	TRIM28	O96017	CHEK2	S417	G414S	414	Missense	distal	-3	no	9.214	8.262	EPSD	GDSC;CCLE	8.561	Loss
CAMK_RAD53_CHEK2_ST	Q13263	TRIM28	O96017	CHEK2	S417	T415I	415	Missense	proximal	-2	no	9.214	8.931	EPSD	GDSC;CCLE	8.561	Down-regulation
CAMK_RAD53_CHEK2_ST	Q13263	TRIM28	O96017	CHEK2	S473	S471F	471	Missense	proximal	-2	no	14.111	12.736	PhosphoSitePlus	GDSC;CCLE	8.561	Down-regulation
CAMK_RAD53_CHEK2_ST	Q13263	TRIM28	O96017	CHEK2	S594	S601L	601	Missense	distal	7	no	11.064	11.088	EPSD	GDSC;CCLE	8.561	Up-regulation
CAMK_RAD53_CHEK2_ST	Q13263	TRIM28	O96017	CHEK2	S598	V605G	605	Missense	distal	7	no	10.812	10.806	EPSD	GDSC	8.561	Down-regulation
CAMK_RAD53_CHEK2_ST	Q13263	TRIM28	O96017	CHEK2	S598	S601L	601	Missense	distal	3	no	10.812	10.981	EPSD	GDSC;CCLE	8.561	Up-regulation
CAMK_RAD53_CHEK2_ST	Q13263	TRIM28	O96017	CHEK2	S600	S601L	601	Missense	proximal	1	no	6.145	8.953	EPSD	GDSC;CCLE	8.561	Gain
CAMK_RAD53_CHEK2_ST	O15151	MDM4	O96017	CHEK2	S367	R363Q	363	Missense	distal	-4	no	16.057	16.155	EPSD;PhosphoSitePlus	GDSC;CCLE	8.561	Up-regulation
CAMK_RAD53_CHEK2_ST	P30307	CDC25C	O96017	CHEK2	S38	E34Q	34	Missense	distal	-4	no	15.082	16.196	EPSD	GDSC;CCLE	8.561	Up-regulation
CAMK_RAD53_CHEK2_ST	P30307	CDC25C	O96017	CHEK2	S451	R458Q	458	Missense	distal	7	no	9.972	9.978	EPSD	GDSC;CCLE	8.561	Up-regulation
CAMK_RAD53_CHEK2_ST	P06400	RB1	O96017	CHEK2	S350	Q344*	344	Missense	distal	-6	no	8.629	7.861	EPSD	GDSC	8.561	Loss
CAMK_RAD53_CHEK2_ST	P06400	RB1	O96017	CHEK2	S780	R787*	787	Missense	distal	7	no	9.151	9.207	EPSD	GDSC	8.561	Up-regulation
CAMK_RAD53_CHEK2_ST	P06400	RB1	O96017	CHEK2	T823	L819V	819	Missense	distal	-4	no	9.137	8.964	EPSD	GDSC;CCLE	8.561	Down-regulation
CAMK_RAD53_CHEK2_ST	O60673	REV3L	O96017	CHEK2	S423	D424E	424	Missense	proximal	1	no	8.976	7.940	EPSD	GDSC;CCLE	8.561	Loss
CAMK_RAD53_CHEK2_ST	O60673	REV3L	O96017	CHEK2	S968	R964Q	964	Missense	distal	-4	no	14.181	14.279	EPSD	GDSC;CCLE	8.561	Up-regulation
CAMK_RAD53_CHEK2_ST	O60673	REV3L	O96017	CHEK2	S1119	S1123F	1123	Missense	distal	4	no	7.964	8.956	EPSD	GDSC;CCLE	8.561	Gain
CAMK_RAD53_CHEK2_ST	O60673	REV3L	O96017	CHEK2	S1130	S1123F	1123	Missense	distal	-7	no	16.877	13.482	EPSD	GDSC;CCLE	8.561	Down-regulation
CAMK_RAD53_CHEK2_ST	O60673	REV3L	O96017	CHEK2	T1225	K1232I	1232	Missense	distal	7	no	11.775	11.801	EPSD	GDSC	8.561	Up-regulation
CAMK_RAD53_CHEK2_ST	O60673	REV3L	O96017	CHEK2	S1515	N1513D	1513	Missense	proximal	-2	no	10.333	10.026	EPSD	GDSC;CCLE	8.561	Down-regulation
CAMK_RAD53_CHEK2_ST	O60673	REV3L	O96017	CHEK2	T1722	G1721D	1721	Missense	proximal	-1	no	12.721	12.918	EPSD	GDSC;CCLE	8.561	Up-regulation
CAMK_RAD53_CHEK2_ST	O60673	REV3L	O96017	CHEK2	S1842	L1839R	1839	Missense	distal	-3	no	2.367	9.979	EPSD	GDSC;CCLE	8.561	Gain
CAMK_RAD53_CHEK2_ST	O60673	REV3L	O96017	CHEK2	S1967	G1974R	1974	Missense	distal	7	no	11.688	11.677	EPSD	GDSC;CCLE	8.561	Down-regulation
CAMK_RAD53_CHEK2_ST	O60673	REV3L	O96017	CHEK2	S1967	P1963L	1963	Missense	distal	-4	no	11.688	10.911	EPSD	GDSC;CCLE	8.561	Down-regulation
CAMK_RAD53_CHEK2_ST	O60673	REV3L	O96017	CHEK2	T2363	T2363I	2363	Missense	central	0	yes	10.748	0.000	EPSD	GDSC;CCLE	8.561	Loss
CAMK_RAD53_CHEK2_ST	O60673	REV3L	O96017	CHEK2	S2430	R2431W	2431	Missense	proximal	1	no	10.190	9.311	EPSD	GDSC;CCLE	8.561	Down-regulation
CAMK_RAD53_CHEK2_ST	O60673	REV3L	O96017	CHEK2	S2884	Q2891*	2891	Missense	distal	7	no	11.433	11.483	EPSD	GDSC	8.561	Up-regulation
CAMK_CAMK2_CAMK2D_ST	Q08289	CACNB2	Q13557	CAMK2D	S218	I225V	225	Missense	distal	7	no	51.476	51.219	EPSD	GDSC	37.605	Down-regulation
CAMK_CAMK2_CAMK2D_ST	Q08289	CACNB2	Q13557	CAMK2D	T219	I225V	225	Missense	distal	6	no	42.441	44.189	EPSD	GDSC	37.605	Up-regulation
CAMK_CAMK2_CAMK2D_ST	Q08289	CACNB2	Q13557	CAMK2D	S550	S557W	557	Missense	distal	7	no	41.780	44.462	EPSD	GDSC	37.605	Up-regulation
CAMK_CAMK2_CAMK2D_ST	Q08289	CACNB2	Q13557	CAMK2D	T554	S557W	557	Missense	distal	3	no	87.151	73.396	EPSD	GDSC	37.605	Down-regulation
CAMK_CAMK2_CAMK2D_ST	Q08289	CACNB2	Q13557	CAMK2D	S609	R608C	608	Missense	proximal	-1	no	47.359	44.964	EPSD	GDSC;CCLE	37.605	Down-regulation
CAMK_CAMK2_CAMK2D_ST	Q08289	CACNB2	Q13557	CAMK2D	S609	V612M	612	Missense	distal	3	no	47.359	54.983	EPSD	GDSC;CCLE	37.605	Up-regulation
CAMK_CAMK2_CAMK2D_ST	P51787	KCNQ1	Q13557	CAMK2D	T96	I93M	93	Missense	distal	-3	no	36.449	39.187	EPSD	GDSC;CCLE	37.605	Gain
CAMK_CAMK2_CAMK2D_ST	P51787	KCNQ1	Q13557	CAMK2D	S199	D202N	202	Missense	distal	3	no	32.890	41.318	EPSD	GDSC	37.605	Gain
CAMK_CAMK2_CAMK2D_ST	P51787	KCNQ1	Q13557	CAMK2D	T470	M476V	476	Missense	distal	6	no	43.465	45.848	EPSD	GDSC;CCLE	37.605	Up-regulation
CAMK_CAMK2_CAMK2D_ST	P56524	HDAC4	Q13557	CAMK2D	T465	R464Q	464	Missense	proximal	-1	no	38.887	35.984	EPSD	GDSC;CCLE	37.605	Loss
CAMK_CAMK2_CAMK2D_ST	Q8WZ42	TTN	Q13557	CAMK2D	T114	R116T	116	Missense	proximal	2	no	48.847	46.381	EPSD	GDSC;CCLE	37.605	Down-regulation
CAMK_CAMK2_CAMK2D_ST	Q8WZ42	TTN	Q13557	CAMK2D	T114	V107I	107	Missense	distal	-7	no	48.847	54.265	EPSD	GDSC;CCLE	37.605	Up-regulation
CAMK_CAMK2_CAMK2D_ST	Q8WZ42	TTN	Q13557	CAMK2D	T219	E226A	226	Missense	distal	7	no	47.347	47.078	EPSD	GDSC;CCLE	37.605	Down-regulation
CAMK_CAMK2_CAMK2D_ST	Q8WZ42	TTN	Q13557	CAMK2D	T219	E222V	222	Missense	distal	3	no	47.347	29.530	EPSD	GDSC;CCLE	37.605	Loss
CAMK_CAMK2_CAMK2D_ST	Q8WZ42	TTN	Q13557	CAMK2D	S308	P309S	309	Missense	proximal	1	no	36.459	40.092	EPSD	GDSC	37.605	Gain
CAMK_CAMK2_CAMK2D_ST	Q8WZ42	TTN	Q13557	CAMK2D	T559	Q557L	557	Missense	proximal	-2	no	46.008	45.619	EPSD	GDSC;CCLE	37.605	Down-regulation
CAMK_CAMK2_CAMK2D_ST	Q8WZ42	TTN	Q13557	CAMK2D	T559	S565F	565	Missense	distal	6	no	46.008	45.206	EPSD	GDSC;CCLE	37.605	Down-regulation
CAMK_CAMK2_CAMK2D_ST	Q8WZ42	TTN	Q13557	CAMK2D	S905	R912S	912	Missense	distal	7	no	40.093	39.935	EPSD	GDSC;CCLE	37.605	Down-regulation
CAMK_CAMK2_CAMK2D_ST	Q8WZ42	TTN	Q13557	CAMK2D	S905	R912C	912	Missense	distal	7	no	40.093	41.913	EPSD	GDSC	37.605	Up-regulation
CAMK_CAMK2_CAMK2D_ST	Q8WZ42	TTN	Q13557	CAMK2D	S905	V904G	904	Missense	proximal	-1	no	40.093	39.529	EPSD	GDSC;CCLE	37.605	Down-regulation
CAMK_CAMK2_CAMK2D_ST	Q8WZ42	TTN	Q13557	CAMK2D	T910	V904G	904	Missense	distal	-6	no	34.525	39.932	EPSD	GDSC;CCLE	37.605	Gain
CAMK_CAMK2_CAMK2D_ST	Q8WZ42	TTN	Q13557	CAMK2D	T1067	T1065I	1065	Missense	proximal	-2	no	41.928	42.906	EPSD	GDSC;CCLE	37.605	Up-regulation
CAMK_CAMK2_CAMK2D_ST	Q8WZ42	TTN	Q13557	CAMK2D	T1067	E1071V	1071	Missense	distal	4	no	41.928	39.693	EPSD	GDSC;CCLE	37.605	Down-regulation
CAMK_CAMK2_CAMK2D_ST	Q8WZ42	TTN	Q13557	CAMK2D	S1465	F1466L	1466	Missense	proximal	1	no	48.117	39.562	EPSD	GDSC	37.605	Down-regulation
CAMK_CAMK2_CAMK2D_ST	Q8WZ42	TTN	Q13557	CAMK2D	T1546	S1539P	1539	Missense	distal	-7	no	38.235	34.983	EPSD	GDSC;CCLE	37.605	Loss
CAMK_CAMK2_CAMK2D_ST	Q8WZ42	TTN	Q13557	CAMK2D	S1622	S1625C	1625	Missense	distal	3	no	37.251	38.287	EPSD	GDSC;CCLE	37.605	Gain
CAMK_CAMK2_CAMK2D_ST	Q8WZ42	TTN	Q13557	CAMK2D	T2088	T2088A	2088	Missense	central	0	yes	40.025	0.000	EPSD	GDSC;CCLE	37.605	Loss
CAMK_CAMK2_CAMK2D_ST	Q8WZ42	TTN	Q13557	CAMK2D	S3208	R3204*	3204	Missense	distal	-4	no	41.212	36.199	EPSD	GDSC	37.605	Loss
CAMK_CAMK2_CAMK2D_ST	Q8WZ42	TTN	Q13557	CAMK2D	S3208	S3213C	3213	Missense	distal	5	no	41.212	40.728	EPSD	GDSC;CCLE	37.605	Down-regulation
CAMK_CAMK2_CAMK2D_ST	Q8WZ42	TTN	Q13557	CAMK2D	T3249	Q3243K	3243	Missense	distal	-6	no	49.492	44.219	EPSD	GDSC;CCLE	37.605	Down-regulation
CAMK_CAMK2_CAMK2D_ST	Q8WZ42	TTN	Q13557	CAMK2D	T17118	T17122A	17122	Missense	distal	4	no	52.106	51.562	EPSD	GDSC	37.605	Down-regulation
CAMK_CAMK2_CAMK2D_ST	Q8WZ42	TTN	Q13557	CAMK2D	T21837	E21835K	21835	Missense	proximal	-2	no	43.273	43.511	EPSD	GDSC	37.605	Up-regulation
CAMK_CAMK2_CAMK2D_ST	Q8WZ42	TTN	Q13557	CAMK2D	S21840	E21835K	21835	Missense	distal	-5	no	42.901	41.725	EPSD	GDSC	37.605	Down-regulation
CAMK_CAMK2_CAMK2D_ST	Q8WZ42	TTN	Q13557	CAMK2D	T22152	L22150F	22150	Missense	proximal	-2	no	55.095	55.228	EPSD	GDSC	37.605	Up-regulation
CAMK_CAMK2_CAMK2D_ST	Q8WZ42	TTN	Q13557	CAMK2D	S25617	S25614N	25614	Missense	distal	-3	no	43.639	40.114	EPSD	GDSC	37.605	Down-regulation
CAMK_CAMK2_CAMK2D_ST	Q8WZ42	TTN	Q13557	CAMK2D	S32133	S32136Y	32136	Missense	distal	3	no	34.449	37.894	EPSD	GDSC	37.605	Gain
CAMK_CAMK2_CAMK2D_ST	Q8WZ42	TTN	Q13557	CAMK2D	S33245	S33247L	33247	Missense	proximal	2	no	45.143	46.591	EPSD	GDSC	37.605	Up-regulation
CAMK_CAMK2_CAMK2D_ST	Q8WZ42	TTN	Q13557	CAMK2D	S33247	S33247L	33247	Missense	central	0	yes	43.037	0.000	EPSD	GDSC	37.605	Loss
CAMK_CAMK2_CAMK2D_ST	Q8WZ42	TTN	Q13557	CAMK2D	S33254	S33247L	33247	Missense	distal	-7	no	49.818	53.157	EPSD	GDSC	37.605	Up-regulation
CAMK_CAMK2_CAMK2D_ST	Q14524	SCN5A	Q13557	CAMK2D	T17	S11I	11	Missense	distal	-6	no	50.514	47.652	EPSD	GDSC;CCLE	37.605	Down-regulation
CAMK_CAMK2_CAMK2D_ST	Q14524	SCN5A	Q13557	CAMK2D	S231	A226V	226	Missense	distal	-5	no	40.944	40.112	EPSD	GDSC	37.605	Down-regulation
CAMK_CAMK2_CAMK2D_ST	Q14524	SCN5A	Q13557	CAMK2D	S516	T512I	512	Missense	distal	-4	no	71.045	69.691	PhosphoSitePlus;EPSD	GDSC;CCLE	37.605	Down-regulation
CAMK_CAMK2_CAMK2D_ST	Q14524	SCN5A	Q13557	CAMK2D	S519	T512I	512	Missense	distal	-7	no	35.202	38.769	EPSD	GDSC;CCLE	37.605	Gain
CAMK_CAMK2_CAMK2D_ST	Q14524	SCN5A	Q13557	CAMK2D	T594	N598H	598	Missense	distal	4	no	79.320	77.697	EPSD;PhosphoSitePlus	GDSC;CCLE	37.605	Down-regulation
CAMK_CAMK2_CAMK2D_ST	Q14524	SCN5A	Q13557	CAMK2D	S671	E678Q	678	Missense	distal	7	no	45.789	44.642	EPSD	GDSC;CCLE	37.605	Down-regulation
CAMK_CAMK2_CAMK2D_ST	Q14524	SCN5A	Q13557	CAMK2D	S671	S671N	671	Missense	central	0	yes	45.789	0.000	EPSD	GDSC;CCLE	37.605	Loss
CAMK_CAMK2_CAMK2D_ST	Q14524	SCN5A	Q13557	CAMK2D	S1937	A1941T	1941	Missense	distal	4	no	38.552	39.097	EPSD	GDSC;CCLE	37.605	Up-regulation
CAMK_CAMK2_CAMK2D_ST	Q14524	SCN5A	Q13557	CAMK2D	S1937	R1944*	1944	Missense	distal	7	no	38.552	41.047	EPSD	GDSC	37.605	Up-regulation
CAMK_CAMK2_CAMK2D_ST	Q14524	SCN5A	Q13557	CAMK2D	S1937	E1938K	1938	Missense	proximal	1	no	38.552	39.027	EPSD	GDSC	37.605	Up-regulation
CAMK_CAMK2_CAMK2D_ST	Q14654	KCNJ11	Q13557	CAMK2D	T224	K222Q	222	Missense	proximal	-2	no	73.333	73.565	PhosphoSitePlus	GDSC;CCLE	37.605	Up-regulation
CAMK_CAMK2_CAMK2D_ST	Q14654	KCNJ11	Q13557	CAMK2D	T341	G334A	334	Missense	distal	-7	no	35.715	38.395	EPSD	GDSC;CCLE	37.605	Gain
CAMK_CAMK2_CAMK2D_ST	Q16625	OCLN	Q13557	CAMK2D	S25	P19L	19	Missense	distal	-6	no	46.884	39.934	EPSD	GDSC;CCLE	37.605	Down-regulation
CAMK_CAMK2_CAMK2D_ST	Q16625	OCLN	Q13557	CAMK2D	S302	V308L	308	Missense	distal	6	no	39.006	37.371	EPSD	GDSC	37.605	Loss
CAMK_CAMK2_CAMK2D_ST	O15084	ANKRD28	Q13557	CAMK2D	S1011	M1018V	1018	Missense	distal	7	no	71.759	71.685	PhosphoSitePlus	GDSC;CCLE	37.605	Down-regulation
AGC_GRK_GRK_GRK6_ST	P08069	IGF1R	P43250	GRK6	S752	T758M	758	Missense	distal	6	no	74.919	50.237	EPSD	GDSC;CCLE	74.824	Loss
AGC_GRK_GRK_GRK6_ST	P08069	IGF1R	P43250	GRK6	S1009	S1009L	1009	Missense	central	0	yes	75.726	0.000	EPSD	GDSC;CCLE	74.824	Loss
AGC_GRK_GRK_GRK6_ST	P08069	IGF1R	P43250	GRK6	S1312	D1318N	1318	Missense	distal	6	no	59.896	77.856	EPSD	GDSC	74.824	Gain
AGC_GRK_GRK_GRK6_ST	P08069	IGF1R	P43250	GRK6	S1321	D1318N	1318	Missense	distal	-3	no	111.736	111.462	PhosphoSitePlus	GDSC	74.824	Down-regulation
AGC_GRK_GRK_GRK6_ST	P08069	IGF1R	P43250	GRK6	S1321	G1322*	1322	Missense	proximal	1	no	111.736	109.269	PhosphoSitePlus	GDSC	74.824	Down-regulation
Other_WNK_WNK3_ST	Q9H4A3	WNK1	Q9BYP7	WNK3	S170	L171F	171	Missense	proximal	1	no	2.460	2.354	EPSD	GDSC;CCLE	2.233	Down-regulation
Other_WNK_WNK3_ST	Q9H4A3	WNK1	Q9BYP7	WNK3	T1913	P1907L	1907	Missense	distal	-6	no	2.817	2.664	EPSD	GDSC	2.233	Down-regulation
Other_WNK_WNK3_ST	Q9H4A3	WNK1	Q9BYP7	WNK3	T1913	G1916V	1916	Missense	distal	3	no	2.817	2.939	EPSD	GDSC;CCLE	2.233	Up-regulation
Other_WNK_WNK3_ST	Q9H4A3	WNK1	Q9BYP7	WNK3	S2037	L2041F	2041	Missense	distal	4	no	2.251	2.324	EPSD	GDSC;CCLE	2.233	Up-regulation
Other_WNK_WNK3_ST	Q9UHW9	SLC12A6	Q9BYP7	WNK3	S96	G99R	99	Missense	distal	3	no	6.778	6.784	EPSD;PhosphoSitePlus	GDSC;CCLE	2.233	Up-regulation
TKL_RIPK_RIPK2_ST	O43353	RIPK2	O43353	RIPK2	S361	S363F	363	Missense	proximal	2	no	3.262	1.248	EPSD	GDSC;CCLE	3.253	Loss
TK_InsR_IGF1R_Y	P35568	IRS1	P08069	IGF1R	Y732	P737S	737	Missense	distal	5	no	3.821	3.952	EPSD;PhosphoSitePlus	GDSC	3.025	Up-regulation
TK_InsR_IGF1R_Y	P35568	IRS1	P08069	IGF1R	Y750	D755A	755	Missense	distal	5	no	2.968	3.060	EPSD	GDSC	3.025	Gain
TK_InsR_IGF1R_Y	P35568	IRS1	P08069	IGF1R	Y896	G902V	902	Missense	distal	6	no	5.717	5.757	EPSD;PhosphoSitePlus	GDSC;CCLE	3.025	Up-regulation
TK_InsR_IGF1R_Y	P35568	IRS1	P08069	IGF1R	Y896	G902R	902	Missense	distal	6	no	5.717	5.646	EPSD;PhosphoSitePlus	GDSC;CCLE	3.025	Down-regulation
TK_InsR_IGF1R_Y	P35568	IRS1	P08069	IGF1R	Y1179	L1177F	1177	Missense	proximal	-2	no	3.926	3.633	EPSD;PhosphoSitePlus	GDSC;CCLE	3.025	Down-regulation
TK_InsR_IGF1R_Y	P08069	IGF1R	P08069	IGF1R	Y131	L133P	133	Missense	proximal	2	no	1.621	3.356	EPSD	GDSC;CCLE	3.025	Gain
TK_InsR_IGF1R_Y	P08069	IGF1R	P08069	IGF1R	Y1346	R1353H	1353	Missense	distal	7	no	4.650	4.642	EPSD	GDSC	3.025	Down-regulation
TK_InsR_IGF1R_Y	O15530	PDPK1	P08069	IGF1R	Y373	N378S	378	Missense	distal	5	no	4.041	4.181	EPSD;PhosphoSitePlus	GDSC;CCLE	3.025	Up-regulation
TK_InsR_IGF1R_Y	O15530	PDPK1	P08069	IGF1R	Y376	N378S	378	Missense	proximal	2	no	5.561	5.883	PhosphoSitePlus;EPSD	GDSC;CCLE	3.025	Up-regulation
TK_InsR_IGF1R_Y	Q03431	PTH1R	P08069	IGF1R	Y496	H502Y	502	Missense	distal	6	no	3.200	3.133	EPSD	GDSC;CCLE	3.025	Down-regulation
TK_InsR_IGF1R_Y	P78324	SIRPA	P08069	IGF1R	Y470	T467A	467	Missense	distal	-3	no	4.343	4.231	EPSD;PhosphoSitePlus	GDSC;CCLE	3.025	Down-regulation
TK_InsR_IGF1R_Y	P78324	SIRPA	P08069	IGF1R	Y496	S494L	494	Missense	proximal	-2	no	3.937	3.247	PhosphoSitePlus;EPSD	GDSC;CCLE	3.025	Down-regulation
TK_InsR_IGF1R_Y	P78324	SIRPA	P08069	IGF1R	Y496	S498G	498	Missense	proximal	2	no	3.937	2.303	PhosphoSitePlus;EPSD	GDSC;CCLE	3.025	Loss
TKL_MLK_MLK_MAP3K10_ST	Q92630	DYRK2	Q02779	MAP3K10	S449	R451*	451	Missense	proximal	2	no	6.181	6.111	EPSD;PhosphoSitePlus	GDSC	2.080	Down-regulation
TKL_MLK_MLK_MAP3K10_ST	Q92630	DYRK2	Q02779	MAP3K10	S471	S474F	474	Missense	distal	3	no	2.994	3.032	EPSD	GDSC;CCLE	2.080	Up-regulation
TKL_MLK_MLK_MAP3K10_ST	Q92630	DYRK2	Q02779	MAP3K10	T525	R523C	523	Missense	proximal	-2	no	2.710	2.762	EPSD	GDSC;CCLE	2.080	Up-regulation
AGC_DMPK_GEK_DMPK_ST	P11831	SRF	Q09013	DMPK	S253	S253C	253	Missense	central	0	yes	2.947	0.000	EPSD	GDSC;CCLE	2.483	Loss
TKL_STKR_STKR2_TGFBR2_ST	O75604	USP2	P37173	TGFBR2	S207	R204C	204	Missense	distal	-3	no	1.937	1.976	PhosphoSitePlus;EPSD	GDSC;CCLE	0.983	Up-regulation
TKL_STKR_STKR2_TGFBR2_ST	O75604	USP2	P37173	TGFBR2	S225	I224L	224	Missense	proximal	-1	no	1.792	1.825	EPSD;PhosphoSitePlus	GDSC;CCLE	0.983	Up-regulation
TKL_STKR_STKR2_TGFBR2_ST	O75604	USP2	P37173	TGFBR2	S225	P230L	230	Missense	distal	5	no	1.792	1.795	EPSD;PhosphoSitePlus	GDSC	0.983	Up-regulation
CMGC_CLK_CLK1_ST	P00519	ABL1	P49759	CLK1	S659	A666D	666	Missense	distal	7	no	53.942	52.026	EPSD	GDSC	52.547	Loss
CMGC_CLK_CLK1_ST	Q96I25	RBM17	P49759	CLK1	S169	G171C	171	Missense	proximal	2	no	64.032	63.714	EPSD	GDSC;CCLE	52.547	Down-regulation
CMGC_CLK_CLK1_ST	Q96I25	RBM17	P49759	CLK1	S288	T283R	283	Missense	distal	-5	no	100.958	105.893	EPSD;PhosphoSitePlus	GDSC;CCLE	52.547	Up-regulation
CMGC_CLK_CLK1_ST	P18031	PTPN1	P49759	CLK1	S70	M74L	74	Missense	distal	4	no	72.205	73.311	EPSD	GDSC;CCLE	52.547	Up-regulation
CMGC_CLK_CLK1_ST	P18031	PTPN1	P49759	CLK1	S70	A69D	69	Missense	proximal	-1	no	72.205	72.209	EPSD	GDSC;CCLE	52.547	Up-regulation
CAMK_CAMKL_BRSK_BRSK2_ST	P49815	TSC2	Q8IWQ3	BRSK2	T993	R988C	988	Missense	distal	-5	no	3.697	3.701	EPSD	GDSC;CCLE	3.184	Up-regulation
CAMK_CAMKL_BRSK_BRSK2_ST	P49815	TSC2	Q8IWQ3	BRSK2	S1379	V1372M	1372	Missense	distal	-7	no	3.716	4.114	EPSD	GDSC;CCLE	3.184	Up-regulation
CAMK_CAMKL_BRSK_BRSK2_ST	P49815	TSC2	Q8IWQ3	BRSK2	S1730	Y1736S	1736	Missense	distal	6	no	4.765	4.906	EPSD	GDSC	3.184	Up-regulation
Atypical_PIKK_DNAPK_PRKDC_ST	P78527	PRKDC	P78527	PRKDC	S210	L217P	217	Missense	distal	7	no	7.748	8.375	EPSD	GDSC	8.283	Gain
Atypical_PIKK_DNAPK_PRKDC_ST	P78527	PRKDC	P78527	PRKDC	S882	E889D	889	Missense	distal	7	no	8.862	8.952	EPSD	GDSC	8.283	Up-regulation
Atypical_PIKK_DNAPK_PRKDC_ST	P78527	PRKDC	P78527	PRKDC	T946	M939V	939	Missense	distal	-7	no	11.193	10.864	EPSD	GDSC;CCLE	8.283	Down-regulation
Atypical_PIKK_DNAPK_PRKDC_ST	P78527	PRKDC	P78527	PRKDC	S1470	H1476Y	1476	Missense	distal	6	no	12.642	12.648	EPSD	GDSC;CCLE	8.283	Up-regulation
Atypical_PIKK_DNAPK_PRKDC_ST	P14859	POU2F1	P78527	PRKDC	S78	S81L	81	Missense	distal	3	no	9.660	9.278	EPSD;PhosphoSitePlus	GDSC	8.283	Down-regulation
Atypical_PIKK_DNAPK_PRKDC_ST	P14859	POU2F1	P78527	PRKDC	S81	S81L	81	Missense	central	0	yes	15.888	0.000	EPSD;PhosphoSitePlus	GDSC	8.283	Loss
Atypical_PIKK_DNAPK_PRKDC_ST	P14859	POU2F1	P78527	PRKDC	S85	S81L	81	Missense	distal	-4	no	15.039	14.595	EPSD;PhosphoSitePlus	GDSC	8.283	Down-regulation
Atypical_PIKK_DNAPK_PRKDC_ST	P14859	POU2F1	P78527	PRKDC	S88	S81L	81	Missense	distal	-7	no	14.542	14.075	EPSD;PhosphoSitePlus	GDSC	8.283	Down-regulation
Atypical_PIKK_DNAPK_PRKDC_ST	P14859	POU2F1	P78527	PRKDC	S141	A134T	134	Missense	distal	-7	no	11.031	10.764	EPSD;PhosphoSitePlus	GDSC;CCLE	8.283	Down-regulation
Atypical_PIKK_DNAPK_PRKDC_ST	P14859	POU2F1	P78527	PRKDC	T226	A221G	221	Missense	distal	-5	no	12.076	11.909	EPSD;PhosphoSitePlus	GDSC;CCLE	8.283	Down-regulation
Atypical_PIKK_DNAPK_PRKDC_ST	P14859	POU2F1	P78527	PRKDC	S322	L316V	316	Missense	distal	-6	no	11.405	10.937	EPSD	GDSC;CCLE	8.283	Down-regulation
Atypical_PIKK_DNAPK_PRKDC_ST	P14859	POU2F1	P78527	PRKDC	S361	S366C	366	Missense	distal	5	no	9.604	9.404	EPSD	GDSC	8.283	Down-regulation
Atypical_PIKK_DNAPK_PRKDC_ST	P14859	POU2F1	P78527	PRKDC	S364	S366C	366	Missense	proximal	2	no	9.327	8.176	EPSD	GDSC	8.283	Loss
Atypical_PIKK_DNAPK_PRKDC_ST	P14859	POU2F1	P78527	PRKDC	S370	I373V	373	Missense	distal	3	no	9.575	9.928	EPSD	GDSC	8.283	Up-regulation
Atypical_PIKK_DNAPK_PRKDC_ST	P14859	POU2F1	P78527	PRKDC	S370	S366C	366	Missense	distal	-4	no	9.575	8.814	EPSD	GDSC	8.283	Down-regulation
Atypical_PIKK_DNAPK_PRKDC_ST	P35637	FUS	P78527	PRKDC	S84	T78P	78	Missense	distal	-6	no	14.024	14.008	EPSD;PhosphoSitePlus	GDSC	8.283	Down-regulation
Atypical_PIKK_DNAPK_PRKDC_ST	P35637	FUS	P78527	PRKDC	S131	P125H	125	Missense	distal	-6	no	14.280	14.500	EPSD;PhosphoSitePlus	GDSC;CCLE	8.283	Up-regulation
Atypical_PIKK_DNAPK_PRKDC_ST	P12956	XRCC6	P78527	PRKDC	S6	M1T	1	Missense	distal	-5	no	10.268	10.497	EPSD;PhosphoSitePlus	GDSC	8.283	Up-regulation
Atypical_PIKK_DNAPK_PRKDC_ST	P12956	XRCC6	P78527	PRKDC	S6	D13N	13	Missense	distal	7	no	10.268	9.602	EPSD;PhosphoSitePlus	GDSC;CCLE	8.283	Down-regulation
Atypical_PIKK_DNAPK_PRKDC_ST	Q96SD1	DCLRE1C	P78527	PRKDC	S548	Q546E	546	Missense	proximal	-2	no	10.820	10.898	EPSD;PhosphoSitePlus	GDSC	8.283	Up-regulation
Atypical_PIKK_DNAPK_PRKDC_ST	Q96SD1	DCLRE1C	P78527	PRKDC	S553	Q546E	546	Missense	distal	-7	no	18.059	17.957	EPSD;PhosphoSitePlus	GDSC	8.283	Down-regulation
Atypical_PIKK_DNAPK_PRKDC_ST	Q13426	XRCC4	P78527	PRKDC	S260	S256C	256	Missense	distal	-4	no	10.057	9.296	EPSD;PhosphoSitePlus	GDSC	8.283	Down-regulation
Atypical_PIKK_DNAPK_PRKDC_ST	Q13426	XRCC4	P78527	PRKDC	S304	S299A	299	Missense	distal	-5	no	8.990	8.854	EPSD;PhosphoSitePlus	GDSC	8.283	Down-regulation
Atypical_PIKK_DNAPK_PRKDC_ST	Q14191	WRN	P78527	PRKDC	S319	T324A	324	Missense	distal	5	no	10.152	10.318	PhosphoSitePlus;EPSD	GDSC	8.283	Up-regulation
Atypical_PIKK_DNAPK_PRKDC_ST	Q14191	WRN	P78527	PRKDC	S426	D433G	433	Missense	distal	7	no	8.927	8.111	EPSD	GDSC;CCLE	8.283	Loss
Atypical_PIKK_DNAPK_PRKDC_ST	Q14191	WRN	P78527	PRKDC	S440	D433G	433	Missense	distal	-7	no	10.299	9.923	EPSD;PhosphoSitePlus	GDSC;CCLE	8.283	Down-regulation
Atypical_PIKK_DNAPK_PRKDC_ST	Q14191	WRN	P78527	PRKDC	S462	D468V	468	Missense	distal	6	no	9.037	9.014	EPSD	GDSC	8.283	Down-regulation
Atypical_PIKK_DNAPK_PRKDC_ST	Q14191	WRN	P78527	PRKDC	S467	D468V	468	Missense	proximal	1	no	9.488	9.904	EPSD;PhosphoSitePlus	GDSC	8.283	Up-regulation
Atypical_PIKK_DNAPK_PRKDC_ST	Q14191	WRN	P78527	PRKDC	T777	T781I	781	Missense	distal	4	no	10.044	10.012	EPSD	GDSC	8.283	Down-regulation
Atypical_PIKK_DNAPK_PRKDC_ST	Q14191	WRN	P78527	PRKDC	T777	T781A	781	Missense	distal	4	no	10.044	10.104	EPSD	GDSC;CCLE	8.283	Up-regulation
Atypical_PIKK_DNAPK_PRKDC_ST	Q14191	WRN	P78527	PRKDC	S1002	A995T	995	Missense	distal	-7	no	9.018	8.751	EPSD	GDSC	8.283	Down-regulation
Atypical_PIKK_DNAPK_PRKDC_ST	Q14191	WRN	P78527	PRKDC	S1002	D996N	996	Missense	distal	-6	no	9.018	9.075	EPSD	GDSC	8.283	Up-regulation
Atypical_PIKK_DNAPK_PRKDC_ST	Q14191	WRN	P78527	PRKDC	S1141	S1141L	1141	Missense	central	0	yes	15.405	0.000	EPSD	GDSC	8.283	Loss
Atypical_PIKK_DNAPK_PRKDC_ST	Q14191	WRN	P78527	PRKDC	S1292	G1298V	1298	Missense	distal	6	no	10.811	10.806	EPSD	GDSC	8.283	Down-regulation
Atypical_PIKK_DNAPK_PRKDC_ST	P04637	TP53	P78527	PRKDC	S6	M1K	1	Missense	distal	-5	no	8.064	8.501	EPSD	GDSC	8.283	Gain
Atypical_PIKK_DNAPK_PRKDC_ST	P04637	TP53	P78527	PRKDC	S33	Q38*	38	Missense	distal	5	no	9.126	8.582	EPSD	GDSC	8.283	Down-regulation
Atypical_PIKK_DNAPK_PRKDC_ST	P04637	TP53	P78527	PRKDC	S37	Q38*	38	Missense	proximal	1	no	12.605	-6.921	PhosphoSitePlus;EPSD	GDSC	8.283	Loss
Atypical_PIKK_DNAPK_PRKDC_ST	P04637	TP53	P78527	PRKDC	S99	K101*	101	Missense	proximal	2	no	10.676	9.484	EPSD	GDSC	8.283	Down-regulation
Atypical_PIKK_DNAPK_PRKDC_ST	P04637	TP53	P78527	PRKDC	S99	Q100*	100	Missense	proximal	1	no	10.676	-8.849	EPSD	GDSC	8.283	Loss
Atypical_PIKK_DNAPK_PRKDC_ST	P04637	TP53	P78527	PRKDC	S99	S94*	94	Missense	distal	-5	no	10.676	10.011	EPSD	GDSC	8.283	Down-regulation
Atypical_PIKK_DNAPK_PRKDC_ST	Q9UGP5	POLL	P78527	PRKDC	S43	R45Q	45	Missense	proximal	2	no	8.144	9.497	EPSD	GDSC	8.283	Gain
Atypical_PIKK_DNAPK_PRKDC_ST	Q9UGP5	POLL	P78527	PRKDC	T204	S199G	199	Missense	distal	-5	no	11.288	10.987	PhosphoSitePlus	GDSC	8.283	Down-regulation
Atypical_PIKK_DNAPK_PRKDC_ST	Q9UGP5	POLL	P78527	PRKDC	T398	A405T	405	Missense	distal	7	no	9.494	8.877	EPSD	GDSC;CCLE	8.283	Down-regulation
Atypical_PIKK_DNAPK_PRKDC_ST	P23025	XPA	P78527	PRKDC	S173	V166A	166	Missense	distal	-7	no	11.286	12.208	EPSD;PhosphoSitePlus	GDSC	8.283	Up-regulation
Atypical_PIKK_DNAPK_PRKDC_ST	Q9H9Q4	NHEJ1	P78527	PRKDC	S55	R57Q	57	Missense	proximal	2	no	10.966	12.319	EPSD;PhosphoSitePlus	GDSC	8.283	Up-regulation
Atypical_PIKK_DNAPK_PRKDC_ST	Q9H9Q4	NHEJ1	P78527	PRKDC	S245	S243I	243	Missense	proximal	-2	no	9.742	9.998	EPSD;PhosphoSitePlus	GDSC;CCLE	8.283	Up-regulation
Atypical_PIKK_DNAPK_PRKDC_ST	Q9H9Q4	NHEJ1	P78527	PRKDC	S263	S268*	268	Missense	distal	5	no	10.763	10.335	EPSD;PhosphoSitePlus	GDSC	8.283	Down-regulation
Atypical_PIKK_DNAPK_PRKDC_ST	Q9H9Q4	NHEJ1	P78527	PRKDC	T266	S268*	268	Missense	proximal	2	no	10.476	7.940	PhosphoSitePlus;EPSD	GDSC	8.283	Loss
Atypical_PIKK_DNAPK_PRKDC_ST	P13010	XRCC5	P78527	PRKDC	S102	Q104*	104	Missense	proximal	2	no	12.610	9.997	EPSD	GDSC	8.283	Down-regulation
Atypical_PIKK_DNAPK_PRKDC_ST	P46527	CDKN1B	P78527	PRKDC	S140	E146Q	146	Missense	distal	6	no	14.217	14.211	PhosphoSitePlus	GDSC;CCLE	8.283	Down-regulation
Atypical_PIKK_DNAPK_PRKDC_ST	P46527	CDKN1B	P78527	PRKDC	S140	P137L	137	Missense	distal	-3	no	14.217	14.017	PhosphoSitePlus	GDSC;CCLE	8.283	Down-regulation
Atypical_PIKK_DNAPK_PRKDC_ST	P46527	CDKN1B	P78527	PRKDC	S178	G177S	177	Missense	proximal	-1	no	9.090	9.353	EPSD	GDSC;CCLE	8.283	Up-regulation
Atypical_PIKK_DNAPK_PRKDC_ST	Q00839	HNRNPU	P78527	PRKDC	T286	V288A	288	Missense	proximal	2	no	7.422	9.053	EPSD	GDSC;CCLE	8.283	Gain
Atypical_PIKK_DNAPK_PRKDC_ST	Q00839	HNRNPU	P78527	PRKDC	S817	S817N	817	Missense	central	0	yes	13.216	0.000	EPSD	GDSC;CCLE	8.283	Loss
Atypical_PIKK_DNAPK_PRKDC_ST	Q00839	HNRNPU	P78527	PRKDC	S817	H821L	821	Missense	distal	4	no	13.216	13.213	EPSD	GDSC;CCLE	8.283	Down-regulation
Atypical_PIKK_DNAPK_PRKDC_ST	P24928	POLR2A	P78527	PRKDC	S209	E207Q	207	Missense	proximal	-2	no	13.680	13.602	EPSD	GDSC;CCLE	8.283	Down-regulation
Atypical_PIKK_DNAPK_PRKDC_ST	P24928	POLR2A	P78527	PRKDC	T732	E738D	738	Missense	distal	6	no	8.341	8.328	EPSD	GDSC;CCLE	8.283	Down-regulation
Atypical_PIKK_DNAPK_PRKDC_ST	P24928	POLR2A	P78527	PRKDC	S1574	P1569L	1569	Missense	distal	-5	no	9.448	9.460	EPSD	GDSC;CCLE	8.283	Up-regulation
Atypical_PIKK_DNAPK_PRKDC_ST	P24928	POLR2A	P78527	PRKDC	S1574	T1568S	1568	Missense	distal	-6	no	9.448	9.796	EPSD	GDSC;CCLE	8.283	Up-regulation
Atypical_PIKK_DNAPK_PRKDC_ST	P24928	POLR2A	P78527	PRKDC	S1616	S1616F	1616	Missense	central	0	yes	8.905	0.000	PhosphoSitePlus;EPSD	GDSC;CCLE	8.283	Loss
Atypical_PIKK_DNAPK_PRKDC_ST	P24928	POLR2A	P78527	PRKDC	S1619	S1616F	1616	Missense	distal	-3	no	8.764	8.746	EPSD	GDSC;CCLE	8.283	Down-regulation
Atypical_PIKK_DNAPK_PRKDC_ST	P24928	POLR2A	P78527	PRKDC	S1621	S1616F	1616	Missense	distal	-5	no	9.489	9.079	EPSD;PhosphoSitePlus	GDSC;CCLE	8.283	Down-regulation
Atypical_PIKK_DNAPK_PRKDC_ST	P24928	POLR2A	P78527	PRKDC	S1847	Y1853H	1853	Missense	distal	6	no	8.448	8.442	EPSD	GDSC;CCLE	8.283	Down-regulation
Atypical_PIKK_DNAPK_PRKDC_ST	P24928	POLR2A	P78527	PRKDC	S1850	Y1853H	1853	Missense	distal	3	no	10.395	10.384	EPSD	GDSC;CCLE	8.283	Down-regulation
Atypical_PIKK_DNAPK_PRKDC_ST	P24928	POLR2A	P78527	PRKDC	S1868	P1862T	1862	Missense	distal	-6	no	8.412	8.428	EPSD	GDSC;CCLE	8.283	Up-regulation
Atypical_PIKK_DNAPK_PRKDC_ST	P24928	POLR2A	P78527	PRKDC	S1955	I1961V	1961	Missense	distal	6	no	8.902	8.925	EPSD	GDSC;CCLE	8.283	Up-regulation
Atypical_PIKK_DNAPK_PRKDC_ST	P24928	POLR2A	P78527	PRKDC	S1962	I1961V	1961	Missense	proximal	-1	no	8.871	9.336	EPSD	GDSC;CCLE	8.283	Up-regulation
Atypical_PIKK_DNAPK_PRKDC_ST	P24928	POLR2A	P78527	PRKDC	S1966	I1961V	1961	Missense	distal	-5	no	8.986	9.298	EPSD	GDSC;CCLE	8.283	Up-regulation
Atypical_PIKK_DNAPK_PRKDC_ST	Q15648	MED1	P78527	PRKDC	S179	E181V	181	Missense	proximal	2	no	8.686	6.395	EPSD	GDSC;CCLE	8.283	Loss
Atypical_PIKK_DNAPK_PRKDC_ST	Q15648	MED1	P78527	PRKDC	S179	Y174*	174	Missense	distal	-5	no	8.686	8.367	EPSD	GDSC	8.283	Down-regulation
Atypical_PIKK_DNAPK_PRKDC_ST	Q15648	MED1	P78527	PRKDC	T212	H205Y	205	Missense	distal	-7	no	9.524	8.945	EPSD	GDSC;CCLE	8.283	Down-regulation
Atypical_PIKK_DNAPK_PRKDC_ST	Q15648	MED1	P78527	PRKDC	T212	Y210C	210	Missense	proximal	-2	no	9.524	9.728	EPSD	GDSC;CCLE	8.283	Up-regulation
Atypical_PIKK_DNAPK_PRKDC_ST	Q15648	MED1	P78527	PRKDC	S719	P722H	722	Missense	distal	3	no	10.712	10.593	EPSD	GDSC;CCLE	8.283	Down-regulation
Atypical_PIKK_DNAPK_PRKDC_ST	Q15648	MED1	P78527	PRKDC	S853	N856D	856	Missense	distal	3	no	8.591	8.584	EPSD	GDSC;CCLE	8.283	Down-regulation
Atypical_PIKK_DNAPK_PRKDC_ST	Q15648	MED1	P78527	PRKDC	S853	S851G	851	Missense	proximal	-2	no	8.591	8.662	EPSD	GDSC;CCLE	8.283	Up-regulation
Atypical_PIKK_DNAPK_PRKDC_ST	Q15648	MED1	P78527	PRKDC	S900	T905I	905	Missense	distal	5	no	11.935	11.738	EPSD	GDSC;CCLE	8.283	Down-regulation
Atypical_PIKK_DNAPK_PRKDC_ST	Q15648	MED1	P78527	PRKDC	S953	M947T	947	Missense	distal	-6	no	10.908	11.041	EPSD	GDSC;CCLE	8.283	Up-regulation
Atypical_PIKK_DNAPK_PRKDC_ST	Q15648	MED1	P78527	PRKDC	S1371	S1375F	1375	Missense	distal	4	no	8.518	8.493	EPSD	GDSC;CCLE	8.283	Down-regulation
Atypical_PIKK_DNAPK_PRKDC_ST	P07954	FH	P78527	PRKDC	S46	A45T	45	Missense	proximal	-1	no	12.660	11.765	EPSD	GDSC	8.283	Down-regulation
Atypical_PIKK_DNAPK_PRKDC_ST	P07954	FH	P78527	PRKDC	S46	E53K	53	Missense	distal	7	no	12.660	11.847	EPSD	GDSC;CCLE	8.283	Down-regulation
Atypical_PIKK_DNAPK_PRKDC_ST	O43918	AIRE	P78527	PRKDC	S107	K114N	114	Missense	distal	7	no	12.995	13.231	EPSD	GDSC	8.283	Up-regulation
Atypical_PIKK_DNAPK_PRKDC_ST	O43918	AIRE	P78527	PRKDC	S107	V104M	104	Missense	distal	-3	no	12.995	12.974	EPSD	GDSC;CCLE	8.283	Down-regulation
Atypical_PIKK_DNAPK_PRKDC_ST	O43918	AIRE	P78527	PRKDC	T232	Q225K	225	Missense	distal	-7	no	9.296	8.939	EPSD	GDSC;CCLE	8.283	Down-regulation
Atypical_PIKK_DNAPK_PRKDC_ST	O43918	AIRE	P78527	PRKDC	T232	F230L	230	Missense	proximal	-2	no	9.296	9.273	EPSD	GDSC;CCLE	8.283	Down-regulation
Atypical_PIKK_DNAPK_PRKDC_ST	P31270	HOXA11	P78527	PRKDC	S98	A99T	99	Missense	proximal	1	no	9.115	3.874	EPSD;PhosphoSitePlus	GDSC	8.283	Loss
Atypical_PIKK_DNAPK_PRKDC_ST	P11831	SRF	P78527	PRKDC	T181	V183G	183	Missense	proximal	2	no	9.818	10.700	EPSD	GDSC;CCLE	8.283	Up-regulation
Atypical_PIKK_DNAPK_PRKDC_ST	P11831	SRF	P78527	PRKDC	S446	S446R	446	Missense	central	0	yes	13.011	0.000	PhosphoSitePlus;EPSD	GDSC;CCLE	8.283	Loss
Atypical_PIKK_DNAPK_PRKDC_ST	P31749	AKT1	P78527	PRKDC	T211	Y215H	215	Missense	distal	4	no	8.453	8.429	EPSD	GDSC;CCLE	8.283	Down-regulation
Atypical_PIKK_DNAPK_PRKDC_ST	P31749	AKT1	P78527	PRKDC	T312	K307N	307	Missense	distal	-5	no	9.481	9.359	EPSD	GDSC;CCLE	8.283	Down-regulation
Atypical_PIKK_DNAPK_PRKDC_ST	P31749	AKT1	P78527	PRKDC	S473	G478S	478	Missense	distal	5	no	9.351	9.467	PhosphoSitePlus	GDSC;CCLE	8.283	Up-regulation
Atypical_PIKK_DNAPK_PRKDC_ST	P31749	AKT1	P78527	PRKDC	S475	G478S	478	Missense	distal	3	no	8.267	8.527	EPSD	GDSC;CCLE	8.283	Gain
Atypical_PIKK_DNAPK_PRKDC_ST	O96017	CHEK2	P78527	PRKDC	T68	S73F	73	Missense	distal	5	no	13.763	13.718	PhosphoSitePlus;EPSD	GDSC;CCLE	8.283	Down-regulation
Atypical_PIKK_DNAPK_PRKDC_ST	Q9BQ15	NABP2	P78527	PRKDC	S182	R178Q	178	Missense	distal	-4	no	11.238	11.937	EPSD	GDSC;CCLE	8.283	Up-regulation
Atypical_PIKK_DNAPK_PRKDC_ST	Q9BQ15	NABP2	P78527	PRKDC	S182	P175A	175	Missense	distal	-7	no	11.238	11.836	EPSD	GDSC;CCLE	8.283	Up-regulation
Atypical_PIKK_DNAPK_PRKDC_ST	P49917	LIG4	P78527	PRKDC	T788	K782N	782	Missense	distal	-6	no	9.154	9.269	EPSD	GDSC;CCLE	8.283	Up-regulation
Atypical_PIKK_DNAPK_PRKDC_ST	P08670	VIM	P78527	PRKDC	S278	A281T	281	Missense	distal	3	no	8.729	8.474	EPSD	GDSC;CCLE	8.283	Down-regulation
Atypical_PIKK_DNAPK_PRKDC_ST	P08670	VIM	P78527	PRKDC	S278	R273C	273	Missense	distal	-5	no	8.729	8.743	EPSD	GDSC;CCLE	8.283	Up-regulation
Atypical_PIKK_DNAPK_PRKDC_ST	P08670	VIM	P78527	PRKDC	S339	A332V	332	Missense	distal	-7	no	10.022	9.100	EPSD	GDSC;CCLE	8.283	Down-regulation
Atypical_PIKK_DNAPK_PRKDC_ST	P08670	VIM	P78527	PRKDC	S430	P432S	432	Missense	proximal	2	no	11.345	11.576	EPSD;PhosphoSitePlus	GDSC;CCLE	8.283	Up-regulation
Atypical_PIKK_DNAPK_PRKDC_ST	P08670	VIM	P78527	PRKDC	S430	S430L	430	Missense	central	0	yes	11.345	0.000	EPSD;PhosphoSitePlus	GDSC;CCLE	8.283	Loss
Atypical_PIKK_DNAPK_PRKDC_ST	P08670	VIM	P78527	PRKDC	S459	T458A	458	Missense	proximal	-1	no	12.148	13.043	PhosphoSitePlus;EPSD	GDSC;CCLE	8.283	Up-regulation
Atypical_PIKK_DNAPK_PRKDC_ST	P18887	XRCC1	P78527	PRKDC	S14	D16Y	16	Missense	proximal	2	no	13.569	11.619	EPSD	GDSC	8.283	Down-regulation
Atypical_PIKK_DNAPK_PRKDC_ST	P18887	XRCC1	P78527	PRKDC	S14	R7L	7	Missense	distal	-7	no	13.569	13.768	EPSD	GDSC	8.283	Up-regulation
Atypical_PIKK_DNAPK_PRKDC_ST	P18887	XRCC1	P78527	PRKDC	S151	S145G	145	Missense	distal	-6	no	9.442	9.146	EPSD	GDSC;CCLE	8.283	Down-regulation
Atypical_PIKK_DNAPK_PRKDC_ST	P18887	XRCC1	P78527	PRKDC	S162	A160T	160	Missense	proximal	-2	no	13.152	13.232	EPSD	GDSC;CCLE	8.283	Up-regulation
Atypical_PIKK_DNAPK_PRKDC_ST	P18887	XRCC1	P78527	PRKDC	S181	N183S	183	Missense	proximal	2	no	7.868	8.791	EPSD	GDSC;CCLE	8.283	Gain
Atypical_PIKK_DNAPK_PRKDC_ST	P18887	XRCC1	P78527	PRKDC	S371	K369R	369	Missense	proximal	-2	no	11.590	11.671	PhosphoSitePlus	GDSC;CCLE	8.283	Up-regulation
Atypical_PIKK_DNAPK_PRKDC_ST	P18887	XRCC1	P78527	PRKDC	T440	Q441*	441	Missense	proximal	1	no	13.840	-5.685	EPSD	GDSC	8.283	Loss
Atypical_PIKK_DNAPK_PRKDC_ST	P18887	XRCC1	P78527	PRKDC	T440	S447L	447	Missense	distal	7	no	13.840	13.086	EPSD	GDSC;CCLE	8.283	Down-regulation
Atypical_PIKK_DNAPK_PRKDC_ST	P18887	XRCC1	P78527	PRKDC	S446	S447L	447	Missense	proximal	1	no	4.110	8.404	EPSD	GDSC;CCLE	8.283	Gain
Atypical_PIKK_DNAPK_PRKDC_ST	P18887	XRCC1	P78527	PRKDC	S447	Q441*	441	Missense	distal	-6	no	9.769	8.550	EPSD	GDSC	8.283	Down-regulation
Atypical_PIKK_DNAPK_PRKDC_ST	P18887	XRCC1	P78527	PRKDC	S447	S447L	447	Missense	central	0	yes	9.769	0.000	EPSD	GDSC;CCLE	8.283	Loss
Atypical_PIKK_DNAPK_PRKDC_ST	P18887	XRCC1	P78527	PRKDC	T453	S447L	447	Missense	distal	-6	no	11.500	11.255	EPSD	GDSC;CCLE	8.283	Down-regulation
Atypical_PIKK_DNAPK_PRKDC_ST	P18887	XRCC1	P78527	PRKDC	T519	P514L	514	Missense	distal	-5	no	8.365	8.378	EPSD	GDSC	8.283	Up-regulation
Atypical_PIKK_DNAPK_PRKDC_ST	Q9NUW8	TDP1	P78527	PRKDC	T11	I12L	12	Missense	proximal	1	no	3.127	11.541	EPSD	GDSC;CCLE	8.283	Gain
Atypical_PIKK_DNAPK_PRKDC_ST	Q9NUW8	TDP1	P78527	PRKDC	S18	S14I	14	Missense	distal	-4	no	8.473	7.210	EPSD	GDSC;CCLE	8.283	Loss
Atypical_PIKK_DNAPK_PRKDC_ST	Q9NUW8	TDP1	P78527	PRKDC	S18	I12L	12	Missense	distal	-6	no	8.473	9.455	EPSD	GDSC;CCLE	8.283	Up-regulation
Atypical_PIKK_DNAPK_PRKDC_ST	Q8IZL8	PELP1	P78527	PRKDC	S7	P9A	9	Missense	proximal	2	no	8.492	8.695	EPSD	GDSC	8.283	Up-regulation
Atypical_PIKK_DNAPK_PRKDC_ST	Q8IZL8	PELP1	P78527	PRKDC	S7	S10F	10	Missense	distal	3	no	8.492	8.206	EPSD	GDSC;CCLE	8.283	Loss
Atypical_PIKK_DNAPK_PRKDC_ST	Q8IZL8	PELP1	P78527	PRKDC	S10	P9A	9	Missense	proximal	-1	no	10.189	10.258	EPSD	GDSC	8.283	Up-regulation
Atypical_PIKK_DNAPK_PRKDC_ST	Q8IZL8	PELP1	P78527	PRKDC	S10	S10F	10	Missense	central	0	yes	10.189	0.000	EPSD	GDSC;CCLE	8.283	Loss
Atypical_PIKK_DNAPK_PRKDC_ST	Q8IZL8	PELP1	P78527	PRKDC	S10	A15T	15	Missense	distal	5	no	10.189	10.023	EPSD	GDSC;CCLE	8.283	Down-regulation
Atypical_PIKK_DNAPK_PRKDC_ST	Q8IZL8	PELP1	P78527	PRKDC	S13	P9A	9	Missense	distal	-4	no	8.997	9.323	EPSD	GDSC	8.283	Up-regulation
Atypical_PIKK_DNAPK_PRKDC_ST	Q8IZL8	PELP1	P78527	PRKDC	S13	S10F	10	Missense	distal	-3	no	8.997	8.979	EPSD	GDSC;CCLE	8.283	Down-regulation
Atypical_PIKK_DNAPK_PRKDC_ST	Q8IZL8	PELP1	P78527	PRKDC	S13	A15T	15	Missense	proximal	2	no	8.997	8.040	EPSD	GDSC;CCLE	8.283	Loss
Atypical_PIKK_DNAPK_PRKDC_ST	P22415	USF1	P78527	PRKDC	S174	S174R	174	Missense	central	0	yes	10.449	0.000	EPSD	GDSC;CCLE	8.283	Loss
Atypical_PIKK_DNAPK_PRKDC_ST	P55895	RAG2	P78527	PRKDC	S20	M22T	22	Missense	proximal	2	no	9.161	9.763	EPSD	GDSC	8.283	Up-regulation
Atypical_PIKK_DNAPK_PRKDC_ST	P55072	VCP	P78527	PRKDC	S459	R465W	465	Missense	distal	6	no	8.674	8.666	EPSD	GDSC;CCLE	8.283	Down-regulation
Atypical_PIKK_DNAPK_PRKDC_ST	Q8TCS8	PNPT1	P78527	PRKDC	S280	T278I	278	Missense	proximal	-2	no	9.559	9.745	EPSD	GDSC	8.283	Up-regulation
Atypical_PIKK_DNAPK_PRKDC_ST	P11387	TOP1	P78527	PRKDC	S112	S111P	111	Missense	proximal	-1	no	11.151	11.491	EPSD	GDSC;CCLE	8.283	Up-regulation
TKL_MLK_LZK_MAP3K12_ST	O14950	MYL12B	Q12852	MAP3K12	T19	R14H	14	Missense	distal	-5	no	4.536	4.502	EPSD;PhosphoSitePlus	GDSC;CCLE	1.313	Down-regulation
TKL_MLK_LZK_MAP3K12_ST	O14950	MYL12B	Q12852	MAP3K12	T19	Q16*	16	Missense	distal	-3	no	4.536	4.448	EPSD;PhosphoSitePlus	GDSC	1.313	Down-regulation
TKL_MLK_LZK_MAP3K12_ST	O14950	MYL12B	Q12852	MAP3K12	S20	R14H	14	Missense	distal	-6	no	4.000	4.048	PhosphoSitePlus;EPSD	GDSC;CCLE	1.313	Up-regulation
TKL_MLK_LZK_MAP3K12_ST	O14950	MYL12B	Q12852	MAP3K12	S20	Q16*	16	Missense	distal	-4	no	4.000	3.956	PhosphoSitePlus;EPSD	GDSC	1.313	Down-regulation
AGC_PKN_PKN1_ST	P10636	MAPT	Q16512	PKN1	S46	Q49H	49	Missense	distal	3	no	60.429	62.923	EPSD	GDSC	59.390	Up-regulation
AGC_PKN_PKN1_ST	P10636	MAPT	Q16512	PKN1	S46	A41V	41	Missense	distal	-5	no	60.429	60.313	EPSD	GDSC;CCLE	59.390	Down-regulation
AGC_PKN_PKN1_ST	P10636	MAPT	Q16512	PKN1	S171	D177V	177	Missense	distal	6	no	79.050	79.138	EPSD	GDSC	59.390	Up-regulation
AGC_PKN_PKN1_ST	P10636	MAPT	Q16512	PKN1	S214	V218G	218	Missense	distal	4	no	64.058	58.921	EPSD;PhosphoSitePlus	GDSC	59.390	Loss
AGC_PKN_PKN1_ST	P10636	MAPT	Q16512	PKN1	T470	A475V	475	Missense	distal	5	no	67.800	67.373	EPSD	GDSC;CCLE	59.390	Down-regulation
AGC_PKN_PKN1_ST	P10636	MAPT	Q16512	PKN1	S637	V635I	635	Missense	proximal	-2	no	88.507	88.573	EPSD	GDSC	59.390	Up-regulation
AGC_PKN_PKN1_ST	P00533	EGFR	Q16512	PKN1	S1070	R1068*	1068	Missense	proximal	-2	no	61.483	50.625	EPSD	GDSC	59.390	Loss
AGC_PKN_PKN1_ST	P00533	EGFR	Q16512	PKN1	S1070	A1076T	1076	Missense	distal	6	no	61.483	60.870	EPSD	GDSC	59.390	Down-regulation
AGC_PKN_PKN1_ST	P00533	EGFR	Q16512	PKN1	S1162	W1157C	1157	Missense	distal	-5	no	60.254	59.220	EPSD	GDSC;CCLE	59.390	Loss
AGC_PKN_PKN1_ST	Q9UKV0	HDAC9	Q16512	PKN1	S663	H657Y	657	Missense	distal	-6	no	60.191	60.079	EPSD	GDSC	59.390	Down-regulation
AGC_PKN_PKN1_ST	O15553	MEFV	Q16512	PKN1	S242	E244A	244	Missense	proximal	2	no	83.262	87.807	EPSD;PhosphoSitePlus	GDSC;CCLE	59.390	Up-regulation
AGC_PKN_PKN1_ST	O15553	MEFV	Q16512	PKN1	S242	T246P	246	Missense	distal	4	no	83.262	81.794	EPSD;PhosphoSitePlus	GDSC;CCLE	59.390	Down-regulation
AGC_PKN_PKN1_ST	P30622	CLIP1	Q16512	PKN1	S348	K346N	346	Missense	proximal	-2	no	57.931	61.948	EPSD	GDSC;CCLE	59.390	Gain
Atypical_PIKK_SMG1_SMG1_ST	P04637	TP53	Q96Q15	SMG1	S33	Q38*	38	Missense	distal	5	no	1.652	1.667	EPSD	GDSC	1.372	Up-regulation
Atypical_PIKK_SMG1_SMG1_ST	P04637	TP53	Q96Q15	SMG1	S37	Q38*	38	Missense	proximal	1	no	2.919	-0.151	EPSD	GDSC	1.372	Loss
Atypical_PIKK_SMG1_SMG1_ST	P04637	TP53	Q96Q15	SMG1	S99	K101*	101	Missense	proximal	2	no	3.102	3.145	EPSD	GDSC	1.372	Up-regulation
Atypical_PIKK_SMG1_SMG1_ST	P04637	TP53	Q96Q15	SMG1	S99	Q100*	100	Missense	proximal	1	no	3.102	0.032	EPSD	GDSC	1.372	Loss
Atypical_PIKK_SMG1_SMG1_ST	P04637	TP53	Q96Q15	SMG1	S99	S94*	94	Missense	distal	-5	no	3.102	3.120	EPSD	GDSC	1.372	Up-regulation
STE_STE11_ASK_MAP3K6_ST	P45983	MAPK8	O95382	MAP3K6	T178	G177*	177	Missense	proximal	-1	no	1.978	2.028	EPSD	GDSC	1.891	Up-regulation
STE_STE11_ASK_MAP3K6_ST	P45983	MAPK8	O95382	MAP3K6	T183	G177*	177	Missense	distal	-6	no	15.332	15.324	PhosphoSitePlus;EPSD	GDSC	1.891	Down-regulation
STE_STE11_ASK_MAP3K6_ST	O95382	MAP3K6	O95382	MAP3K6	T793	L786P	786	Missense	distal	-7	no	2.019	2.048	EPSD	GDSC;CCLE	1.891	Up-regulation
STE_STE11_ASK_MAP3K6_ST	O95382	MAP3K6	O95382	MAP3K6	T806	T806A	806	Missense	central	0	yes	16.036	0.000	PhosphoSitePlus	GDSC	1.891	Loss
STE_STE11_ASK_MAP3K6_ST	O95382	MAP3K6	O95382	MAP3K6	T806	G809E	809	Missense	distal	3	no	16.036	15.946	PhosphoSitePlus	GDSC	1.891	Down-regulation
STE_STE11_ASK_MAP3K6_ST	O95382	MAP3K6	O95382	MAP3K6	T944	P946L	946	Missense	proximal	2	no	3.665	3.790	EPSD	GDSC	1.891	Up-regulation
CAMK_DAPK_DAPK_DAPK1_ST	P53355	DAPK1	P53355	DAPK1	S57	R58L	58	Missense	proximal	1	no	10.150	9.795	EPSD	GDSC	8.849	Down-regulation
CAMK_DAPK_DAPK_DAPK1_ST	P53355	DAPK1	P53355	DAPK1	S308	Q307K	307	Missense	proximal	-1	no	14.981	14.604	PhosphoSitePlus	GDSC	8.849	Down-regulation
CAMK_DAPK_DAPK_DAPK1_ST	P53355	DAPK1	P53355	DAPK1	S308	R302Q	302	Missense	distal	-6	no	14.981	14.384	PhosphoSitePlus	GDSC;CCLE	8.849	Down-regulation
CAMK_DAPK_DAPK_DAPK1_ST	P53355	DAPK1	P53355	DAPK1	S313	Q307K	307	Missense	distal	-6	no	15.405	14.622	EPSD	GDSC	8.849	Down-regulation
CAMK_DAPK_DAPK_DAPK1_ST	P53355	DAPK1	P53355	DAPK1	S728	P732A	732	Missense	distal	4	no	9.630	9.462	EPSD	GDSC;CCLE	8.849	Down-regulation
CAMK_DAPK_DAPK_DAPK1_ST	O95786	DDX58	P53355	DAPK1	T770	E773K	773	Missense	distal	3	no	15.226	15.355	EPSD;PhosphoSitePlus	GDSC	8.849	Up-regulation
CAMK_DAPK_DAPK_DAPK1_ST	Q96RR4	CAMKK2	P53355	DAPK1	T350	S345F	345	Missense	distal	-5	no	9.990	9.866	EPSD	GDSC;CCLE	8.849	Down-regulation
CAMK_DAPK_DAPK_DAPK1_ST	Q96RR4	CAMKK2	P53355	DAPK1	T350	P351L	351	Missense	proximal	1	no	9.990	9.522	EPSD	GDSC;CCLE	8.849	Down-regulation
CAMK_DAPK_DAPK_DAPK1_ST	Q96RR4	CAMKK2	P53355	DAPK1	S509	R508C	508	Missense	proximal	-1	no	9.171	8.155	EPSD	GDSC	8.849	Loss
CAMK_DAPK_DAPK_DAPK1_ST	Q96RR4	CAMKK2	P53355	DAPK1	S511	R508C	508	Missense	distal	-3	no	15.718	10.891	PhosphoSitePlus	GDSC	8.849	Down-regulation
CAMK_DAPK_DAPK_DAPK1_ST	Q00613	HSF1	P53355	DAPK1	S338	V345I	345	Missense	distal	7	no	9.574	9.333	EPSD	GDSC	8.849	Down-regulation
CAMK_DAPK_DAPK_DAPK1_ST	O14950	MYL12B	P53355	DAPK1	S20	R14H	14	Missense	distal	-6	no	13.300	10.835	PhosphoSitePlus	GDSC;CCLE	8.849	Down-regulation
CAMK_DAPK_DAPK_DAPK1_ST	O14950	MYL12B	P53355	DAPK1	S20	Q16*	16	Missense	distal	-4	no	13.300	12.997	PhosphoSitePlus	GDSC	8.849	Down-regulation
CAMK_DAPK_DAPK_DAPK1_ST	Q14457	BECN1	P53355	DAPK1	T426	L429P	429	Missense	distal	3	no	8.623	9.170	EPSD	GDSC;CCLE	8.849	Gain
CAMK_DAPK_DAPK_DAPK1_ST	P04637	TP53	P53355	DAPK1	S269	E271*	271	Missense	proximal	2	no	15.697	16.383	EPSD;PhosphoSitePlus	GDSC	8.849	Up-regulation
CAMK_DAPK_DAPK_DAPK1_ST	P04637	TP53	P53355	DAPK1	S314	Q317*	317	Missense	distal	3	no	6.512	9.065	EPSD	GDSC	8.849	Gain
CAMK_DAPK_DAPK_DAPK1_ST	Q13526	PIN1	P53355	DAPK1	S98	D102E	102	Missense	distal	4	no	9.643	9.072	EPSD	GDSC;CCLE	8.849	Down-regulation
CAMK_DAPK_DAPK_DAPK1_ST	P25205	MCM3	P53355	DAPK1	S160	A167S	167	Missense	distal	7	no	15.355	16.142	PhosphoSitePlus	GDSC;CCLE	8.849	Up-regulation
CAMK_DAPK_DAPK_DAPK1_ST	P25205	MCM3	P53355	DAPK1	S604	S611Y	611	Missense	distal	7	no	9.212	8.397	EPSD	GDSC;CCLE	8.849	Loss
CAMK_DAPK_DAPK_DAPK1_ST	P25205	MCM3	P53355	DAPK1	S611	A615T	615	Missense	distal	4	no	9.748	10.085	EPSD	GDSC;CCLE	8.849	Up-regulation
CAMK_DAPK_DAPK_DAPK1_ST	P25205	MCM3	P53355	DAPK1	S611	S611Y	611	Missense	central	0	yes	9.748	0.000	EPSD	GDSC;CCLE	8.849	Loss
CAMK_DAPK_DAPK_DAPK1_ST	P25205	MCM3	P53355	DAPK1	T620	A615T	615	Missense	distal	-5	no	9.860	9.967	EPSD	GDSC;CCLE	8.849	Up-regulation
CAMK_DAPK_DAPK_DAPK1_ST	Q13224	GRIN2B	P53355	DAPK1	S865	C871*	871	Missense	distal	6	no	9.141	10.144	EPSD	GDSC	8.849	Up-regulation
CAMK_DAPK_DAPK_DAPK1_ST	Q13224	GRIN2B	P53355	DAPK1	T894	I898V	898	Missense	distal	4	no	9.847	10.350	EPSD	GDSC;CCLE	8.849	Up-regulation
CAMK_PKD_PRKD1_ST	P35670	ATP7B	Q15139	PRKD1	S23	S20Y	20	Missense	distal	-3	no	4.625	3.118	EPSD	GDSC;CCLE	4.507	Loss
CAMK_PKD_PRKD1_ST	P35670	ATP7B	Q15139	PRKD1	S342	P346L	346	Missense	distal	4	no	7.178	7.176	EPSD	GDSC;CCLE	4.507	Down-regulation
CAMK_PKD_PRKD1_ST	O15273	TCAP	Q15139	PRKD1	S157	R153H	153	Missense	distal	-4	no	9.788	9.783	PhosphoSitePlus;EPSD	GDSC	4.507	Down-regulation
CAMK_PKD_PRKD1_ST	P35222	CTNNB1	Q15139	PRKD1	S552	R549H	549	Missense	distal	-3	no	8.246	4.259	EPSD	GDSC;CCLE	4.507	Loss
CAMK_PKD_PRKD1_ST	P35222	CTNNB1	Q15139	PRKD1	S675	Y670*	670	Missense	distal	-5	no	5.030	5.769	EPSD	GDSC	4.507	Up-regulation
CAMK_PKD_PRKD1_ST	Q8WYL5	SSH1	Q15139	PRKD1	S237	A239T	239	Missense	proximal	2	no	6.430	6.322	EPSD	GDSC;CCLE	4.507	Down-regulation
CAMK_PKD_PRKD1_ST	Q92934	BAD	Q15139	PRKD1	S134	T137K	137	Missense	distal	3	no	10.798	10.805	EPSD	GDSC	4.507	Up-regulation
CAMK_PKD_PRKD1_ST	Q92934	BAD	Q15139	PRKD1	S134	L129F	129	Missense	distal	-5	no	10.798	7.646	EPSD	GDSC	4.507	Down-regulation
CAMK_PKD_PRKD1_ST	Q92934	BAD	Q15139	PRKD1	S145	F151L	151	Missense	distal	6	no	6.629	6.608	EPSD	GDSC;CCLE	4.507	Down-regulation
CAMK_PKD_PRKD1_ST	Q9UQL6	HDAC5	Q15139	PRKD1	S1108	E1114Q	1114	Missense	distal	6	no	7.248	7.234	EPSD	GDSC	4.507	Down-regulation
CAMK_PKD_PRKD1_ST	Q96QB1	DLC1	Q15139	PRKD1	S306	Q303R	303	Missense	distal	-3	no	0.874	5.286	EPSD	GDSC;CCLE	4.507	Gain
CAMK_PKD_PRKD1_ST	Q96QB1	DLC1	Q15139	PRKD1	S354	R347*	347	Missense	distal	-7	no	5.871	5.300	EPSD	GDSC	4.507	Down-regulation
CAMK_PKD_PRKD1_ST	Q96QB1	DLC1	Q15139	PRKD1	S378	P383S	383	Missense	distal	5	no	6.214	6.260	EPSD	GDSC;CCLE	4.507	Up-regulation
CAMK_PKD_PRKD1_ST	Q96QB1	DLC1	Q15139	PRKD1	S620	I622V	622	Missense	proximal	2	no	6.628	6.622	EPSD	GDSC;CCLE	4.507	Down-regulation
CAMK_PKD_PRKD1_ST	Q96QB1	DLC1	Q15139	PRKD1	S733	N736S	736	Missense	distal	3	no	8.400	8.413	EPSD	GDSC;CCLE	4.507	Up-regulation
CAMK_PKD_PRKD1_ST	Q96QB1	DLC1	Q15139	PRKD1	S735	N736S	736	Missense	proximal	1	no	7.891	7.892	EPSD	GDSC;CCLE	4.507	Up-regulation
CAMK_PKD_PRKD1_ST	Q96QB1	DLC1	Q15139	PRKD1	S764	V759F	759	Missense	distal	-5	no	7.333	5.714	EPSD	GDSC;CCLE	4.507	Down-regulation
CAMK_PKD_PRKD1_ST	Q96QB1	DLC1	Q15139	PRKD1	S766	V759F	759	Missense	distal	-7	no	7.348	7.387	EPSD	GDSC;CCLE	4.507	Up-regulation
CAMK_PKD_PRKD1_ST	Q96QB1	DLC1	Q15139	PRKD1	S842	F843L	843	Missense	proximal	1	no	7.280	7.281	EPSD	GDSC;CCLE	4.507	Up-regulation
CAMK_PKD_PRKD1_ST	Q96QB1	DLC1	Q15139	PRKD1	S856	N855S	855	Missense	proximal	-1	no	8.730	8.890	EPSD	GDSC;CCLE	4.507	Up-regulation
CAMK_PKD_PRKD1_ST	Q96QB1	DLC1	Q15139	PRKD1	S1296	E1301*	1301	Missense	distal	5	no	5.016	4.980	EPSD	GDSC	4.507	Down-regulation
CAMK_PKD_PRKD1_ST	Q96QB1	DLC1	Q15139	PRKD1	S1296	R1292*	1292	Missense	distal	-4	no	5.016	5.006	EPSD	GDSC	4.507	Down-regulation
CAMK_PKD_PRKD1_ST	Q96QB1	DLC1	Q15139	PRKD1	S1355	E1353*	1353	Missense	proximal	-2	no	4.622	4.196	EPSD	GDSC	4.507	Loss
CAMK_PKD_PRKD1_ST	O00429	DNM1L	Q15139	PRKD1	T78	E82*	82	Missense	distal	4	no	4.914	4.921	EPSD	GDSC	4.507	Up-regulation
CAMK_PKD_PRKD1_ST	O00429	DNM1L	Q15139	PRKD1	T79	E82*	82	Missense	distal	3	no	5.881	5.868	EPSD	GDSC	4.507	Down-regulation
CAMK_PKD_PRKD1_ST	O00429	DNM1L	Q15139	PRKD1	S175	L169V	169	Missense	distal	-6	no	5.588	5.601	EPSD	GDSC	4.507	Up-regulation
CAMK_PKD_PRKD1_ST	O00429	DNM1L	Q15139	PRKD1	S194	T189R	189	Missense	distal	-5	no	4.179	4.905	EPSD	GDSC	4.507	Gain
CAMK_PKD_PRKD1_ST	O00429	DNM1L	Q15139	PRKD1	S529	E523*	523	Missense	distal	-6	no	5.617	5.601	EPSD	GDSC	4.507	Down-regulation
CAMK_PKD_PRKD1_ST	O00429	DNM1L	Q15139	PRKD1	S544	A551T	551	Missense	distal	7	no	4.546	4.545	EPSD	GDSC;CCLE	4.507	Down-regulation
CAMK_PKD_PRKD1_ST	O00429	DNM1L	Q15139	PRKD1	S544	P547L	547	Missense	distal	3	no	4.546	4.548	EPSD	GDSC	4.507	Up-regulation
CAMK_PKD_PRKD1_ST	O00429	DNM1L	Q15139	PRKD1	S544	A550D	550	Missense	distal	6	no	4.546	4.588	EPSD	GDSC	4.507	Up-regulation
CAMK_PKD_PRKD1_ST	O00429	DNM1L	Q15139	PRKD1	S552	P547L	547	Missense	distal	-5	no	2.737	5.582	EPSD	GDSC	4.507	Gain
CAMK_PKD_PRKD1_ST	O00429	DNM1L	Q15139	PRKD1	S637	V632A	632	Missense	distal	-5	no	9.050	8.645	PhosphoSitePlus	GDSC;CCLE	4.507	Down-regulation
CAMK_PKD_PRKD1_ST	Q15276	RABEP1	Q15139	PRKD1	S162	E166G	166	Missense	distal	4	no	11.521	11.540	EPSD	GDSC;CCLE	4.507	Up-regulation
CAMK_PKD_PRKD1_ST	Q15276	RABEP1	Q15139	PRKD1	S357	S362*	362	Missense	distal	5	no	4.699	4.627	EPSD	GDSC	4.507	Down-regulation
CAMK_PKD_PRKD1_ST	Q15276	RABEP1	Q15139	PRKD1	S362	E364K	364	Missense	proximal	2	no	4.491	4.509	EPSD	GDSC;CCLE	4.507	Gain
CAMK_PKD_PRKD1_ST	Q15276	RABEP1	Q15139	PRKD1	S374	T371S	371	Missense	distal	-3	no	4.566	3.641	EPSD	GDSC;CCLE	4.507	Loss
CAMK_PKD_PRKD1_ST	Q15276	RABEP1	Q15139	PRKD1	S416	S419Y	419	Missense	distal	3	no	5.325	5.296	EPSD	GDSC;CCLE	4.507	Down-regulation
CAMK_PKD_PRKD1_ST	Q15276	RABEP1	Q15139	PRKD1	S447	A445V	445	Missense	proximal	-2	no	5.023	2.867	EPSD	GDSC;CCLE	4.507	Loss
CAMK_PKD_PRKD1_ST	O75628	REM1	Q15139	PRKD1	S18	A17V	17	Missense	proximal	-1	no	10.863	10.684	PhosphoSitePlus	GDSC	4.507	Down-regulation
CAMK_PKD_PRKD1_ST	O75628	REM1	Q15139	PRKD1	T19	A17V	17	Missense	proximal	-2	no	6.291	4.135	EPSD	GDSC	4.507	Loss
CAMK_PKD_PRKD1_ST	O75628	REM1	Q15139	PRKD1	S51	G47S	47	Missense	distal	-4	no	5.252	5.262	EPSD	GDSC;CCLE	4.507	Up-regulation
CAMK_PKD_PRKD1_ST	O75628	REM1	Q15139	PRKD1	S51	R45Q	45	Missense	distal	-6	no	5.252	5.251	EPSD	GDSC;CCLE	4.507	Down-regulation
CAMK_PKD_PRKD1_ST	O75628	REM1	Q15139	PRKD1	S250	R246C	246	Missense	distal	-4	no	10.549	10.541	EPSD	GDSC;CCLE	4.507	Down-regulation
CAMK_PKD_PRKD1_ST	Q99683	MAP3K5	Q15139	PRKD1	S83	S83C	83	Missense	central	0	yes	4.917	0.000	EPSD	GDSC;CCLE	4.507	Loss
CAMK_PKD_PRKD1_ST	Q99683	MAP3K5	Q15139	PRKD1	S269	S267R	267	Missense	proximal	-2	no	4.162	6.007	EPSD	GDSC	4.507	Gain
CAMK_PKD_PRKD1_ST	Q99683	MAP3K5	Q15139	PRKD1	S763	G760R	760	Missense	distal	-3	no	2.938	7.705	EPSD	GDSC	4.507	Gain
CAMK_PKD_PRKD1_ST	Q99683	MAP3K5	Q15139	PRKD1	T1059	D1063Y	1063	Missense	distal	4	no	6.060	6.066	EPSD	GDSC	4.507	Up-regulation
CAMK_PKD_PRKD1_ST	O96013	PAK4	Q15139	PRKD1	T213	R218Q	218	Missense	distal	5	no	4.657	4.634	EPSD	GDSC	4.507	Down-regulation
CAMK_PKD_PRKD1_ST	O96013	PAK4	Q15139	PRKD1	S267	G260A	260	Missense	distal	-7	no	4.506	4.980	EPSD	GDSC;CCLE	4.507	Gain
CAMK_PKD_PRKD1_ST	P27986	PIK3R1	Q15139	PRKD1	S652	L647P	647	Missense	distal	-5	no	9.404	6.559	EPSD	GDSC;CCLE	4.507	Down-regulation
CAMK_PKD_PRKD1_ST	P31749	AKT1	Q15139	PRKD1	T72	I75M	75	Missense	distal	3	no	4.787	4.796	EPSD	GDSC;CCLE	4.507	Up-regulation
CAMK_PKD_PRKD1_ST	Q14896	MYBPC3	Q15139	PRKD1	S830	R835L	835	Missense	distal	5	no	5.021	4.943	EPSD	GDSC;CCLE	4.507	Down-regulation
CAMK_PKD_PRKD1_ST	Q14896	MYBPC3	Q15139	PRKD1	S830	A833T	833	Missense	distal	3	no	5.021	5.001	EPSD	GDSC	4.507	Down-regulation
CAMK_PKD_PRKD1_ST	O60331	PIP5K1C	Q15139	PRKD1	S541	T543M	543	Missense	proximal	2	no	7.574	7.602	EPSD	GDSC	4.507	Up-regulation
CAMK_PKD_PRKD1_ST	O60331	PIP5K1C	Q15139	PRKD1	T553	R550G	550	Missense	distal	-3	no	8.040	3.273	EPSD	GDSC	4.507	Loss
CAMK_PKD_PRKD1_ST	O60331	PIP5K1C	Q15139	PRKD1	S555	R550G	550	Missense	distal	-5	no	7.198	6.062	EPSD	GDSC	4.507	Down-regulation
CAMK_PKD_PRKD1_ST	Q15139	PRKD1	Q15139	PRKD1	S397	N403S	403	Missense	distal	6	no	7.330	7.302	EPSD	GDSC	4.507	Down-regulation
CAMK_PKD_PRKD1_ST	Q15139	PRKD1	Q15139	PRKD1	S829	K826E	826	Missense	distal	-3	no	7.429	5.978	EPSD	GDSC;CCLE	4.507	Down-regulation
CAMK_PKD_PRKD1_ST	Q15139	PRKD1	Q15139	PRKD1	S910	G906D	906	Missense	distal	-4	no	7.394	7.393	EPSD;PhosphoSitePlus	GDSC;CCLE	4.507	Down-regulation
CAMK_PKD_PRKD1_ST	Q15139	PRKD1	Q15139	PRKD1	S910	G906S	906	Missense	distal	-4	no	7.394	7.403	EPSD;PhosphoSitePlus	GDSC	4.507	Up-regulation
CAMK_PKD_PRKD1_ST	Q15139	PRKD1	Q15139	PRKD1	S910	K903E	903	Missense	distal	-7	no	7.394	7.320	EPSD;PhosphoSitePlus	GDSC;CCLE	4.507	Down-regulation
CAMK_PKD_PRKD1_ST	Q13936	CACNA1C	Q15139	PRKD1	S1535	Y1529F	1529	Missense	distal	-6	no	7.690	7.694	EPSD	GDSC;CCLE	4.507	Up-regulation
CAMK_PKD_PRKD1_ST	Q13936	CACNA1C	Q15139	PRKD1	S1718	R1714*	1714	Missense	distal	-4	no	7.118	7.108	EPSD	GDSC	4.507	Down-regulation
CAMK_PKD_PRKD1_ST	Q13936	CACNA1C	Q15139	PRKD1	S1736	A1738T	1738	Missense	proximal	2	no	5.230	5.122	EPSD	GDSC;CCLE	4.507	Down-regulation
CAMK_PKD_PRKD1_ST	Q14247	CTTN	Q15139	PRKD1	S113	V115A	115	Missense	proximal	2	no	8.345	8.476	EPSD	GDSC;CCLE	4.507	Up-regulation
CAMK_PKD_PRKD1_ST	P05412	JUN	Q15139	PRKD1	S84	H87R	87	Missense	distal	3	no	4.633	4.641	EPSD	GDSC;CCLE	4.507	Up-regulation
CAMK_PKD_PRKD1_ST	P48426	PIP4K2A	Q15139	PRKD1	S222	R219K	219	Missense	distal	-3	no	7.734	5.063	EPSD	GDSC	4.507	Down-regulation
CAMK_PKD_PRKD1_ST	P48426	PIP4K2A	Q15139	PRKD1	S222	E220K	220	Missense	proximal	-2	no	7.734	8.515	EPSD	GDSC	4.507	Up-regulation
CAMK_PKD_PRKD1_ST	Q9Y3E5	PTRH2	Q15139	PRKD1	S141	K134E	134	Missense	distal	-7	no	4.997	4.922	EPSD	GDSC;CCLE	4.507	Down-regulation
CAMK_PKD_PRKD1_ST	Q9BST9	RTKN	Q15139	PRKD1	T518	D522N	522	Missense	distal	4	no	4.736	4.725	EPSD	GDSC	4.507	Down-regulation
CAMK_PKD_PRKD1_ST	Q9BST9	RTKN	Q15139	PRKD1	S520	D522N	522	Missense	proximal	2	no	7.065	7.111	EPSD	GDSC	4.507	Up-regulation
CAMK_PKD_PRKD1_ST	Q12809	KCNH2	Q15139	PRKD1	S354	P347S	347	Missense	distal	-7	no	4.638	4.751	EPSD	GDSC	4.507	Up-regulation
CAMK_PKD_PRKD1_ST	Q12809	KCNH2	Q15139	PRKD1	S354	E357K	357	Missense	distal	3	no	4.638	4.637	EPSD	GDSC;CCLE	4.507	Down-regulation
CAMK_PKD_PRKD1_ST	Q12809	KCNH2	Q15139	PRKD1	S890	R894G	894	Missense	distal	4	no	9.635	9.665	EPSD	GDSC;CCLE	4.507	Up-regulation
CAMK_PKD_PRKD1_ST	Q12809	KCNH2	Q15139	PRKD1	T895	R894G	894	Missense	proximal	-1	no	6.730	6.388	EPSD	GDSC;CCLE	4.507	Down-regulation
CAMK_PKD_PRKD1_ST	P05549	TFAP2A	Q15139	PRKD1	S219	L218F	218	Missense	proximal	-1	no	4.733	4.502	EPSD	GDSC;CCLE	4.507	Loss
CAMK_PKD_PRKD1_ST	P05549	TFAP2A	Q15139	PRKD1	S225	L218F	218	Missense	distal	-7	no	5.134	5.278	EPSD	GDSC;CCLE	4.507	Up-regulation
CAMK_PKD_PRKD1_ST	P05549	TFAP2A	Q15139	PRKD1	S326	F320L	320	Missense	distal	-6	no	9.393	9.388	EPSD;PhosphoSitePlus	GDSC;CCLE	4.507	Down-regulation
CAMK_PKD_PRKD1_ST	Q13671	RIN1	Q15139	PRKD1	S611	R607Q	607	Missense	distal	-4	no	10.313	10.309	EPSD	GDSC;CCLE	4.507	Down-regulation
CAMK_PKD_PRKD1_ST	Q13671	RIN1	Q15139	PRKD1	T695	A688T	688	Missense	distal	-7	no	4.902	4.642	EPSD	GDSC;CCLE	4.507	Down-regulation
CAMK_PKD_PRKD1_ST	P16144	ITGB4	Q15139	PRKD1	S397	T393A	393	Missense	distal	-4	no	4.644	4.649	EPSD	GDSC	4.507	Up-regulation
CAMK_PKD_PRKD1_ST	P16144	ITGB4	Q15139	PRKD1	T829	P835A	835	Missense	distal	6	no	6.419	6.398	EPSD	GDSC	4.507	Down-regulation
CAMK_PKD_PRKD1_ST	P16144	ITGB4	Q15139	PRKD1	T837	D836N	836	Missense	proximal	-1	no	4.490	4.584	EPSD	GDSC;CCLE	4.507	Gain
CAMK_PKD_PRKD1_ST	P16144	ITGB4	Q15139	PRKD1	T837	P835A	835	Missense	proximal	-2	no	4.490	5.103	EPSD	GDSC	4.507	Gain
CAMK_PKD_PRKD1_ST	P16144	ITGB4	Q15139	PRKD1	S1140	P1133T	1133	Missense	distal	-7	no	5.892	5.836	EPSD	GDSC;CCLE	4.507	Down-regulation
CAMK_PKD_PRKD1_ST	P16144	ITGB4	Q15139	PRKD1	S1140	A1137V	1137	Missense	distal	-3	no	5.892	2.942	EPSD	GDSC;CCLE	4.507	Loss
CAMK_PKD_PRKD1_ST	P16144	ITGB4	Q15139	PRKD1	S1511	T1514P	1514	Missense	distal	3	no	6.409	6.412	EPSD	GDSC	4.507	Up-regulation
CAMK_PKD_PRKD1_ST	P16144	ITGB4	Q15139	PRKD1	S1604	V1600M	1600	Missense	distal	-4	no	7.520	7.525	EPSD	GDSC;CCLE	4.507	Up-regulation
CAMK_PKD_PRKD1_ST	P16144	ITGB4	Q15139	PRKD1	S1604	W1608*	1608	Missense	distal	4	no	7.520	7.514	EPSD	GDSC	4.507	Down-regulation
CAMK_PKD_PRKD1_ST	P16144	ITGB4	Q15139	PRKD1	S1791	T1793P	1793	Missense	proximal	2	no	5.362	5.388	EPSD	GDSC	4.507	Up-regulation
CAMK_PKD_PRKD1_ST	P16144	ITGB4	Q15139	PRKD1	S1791	R1794Q	1794	Missense	distal	3	no	5.362	5.354	EPSD	GDSC	4.507	Down-regulation
CAMK_PKD_PRKD1_ST	P16144	ITGB4	Q15139	PRKD1	T1797	T1793P	1793	Missense	distal	-4	no	7.128	7.130	EPSD	GDSC	4.507	Up-regulation
CAMK_PKD_PRKD1_ST	P16144	ITGB4	Q15139	PRKD1	T1797	R1794Q	1794	Missense	distal	-3	no	7.128	2.716	EPSD	GDSC	4.507	Loss
CAMK_PKD_PRKD1_ST	P02686	MBP	Q15139	PRKD1	S16	E13K	13	Missense	distal	-3	no	4.408	5.858	EPSD	GDSC;CCLE	4.507	Gain
CAMK_PKD_PRKD1_ST	P02686	MBP	Q15139	PRKD1	S40	E41G	41	Missense	proximal	1	no	8.257	8.256	EPSD	GDSC;CCLE	4.507	Down-regulation
CAMK_PKD_PRKD1_ST	P02686	MBP	Q15139	PRKD1	S40	V45A	45	Missense	distal	5	no	8.257	8.339	EPSD	GDSC;CCLE	4.507	Up-regulation
CAMK_PKD_PRKD1_ST	P02686	MBP	Q15139	PRKD1	S40	V45L	45	Missense	distal	5	no	8.257	8.259	EPSD	GDSC;CCLE	4.507	Up-regulation
CAMK_PKD_PRKD1_ST	P02686	MBP	Q15139	PRKD1	S96	H90R	90	Missense	distal	-6	no	7.949	7.962	EPSD	GDSC;CCLE	4.507	Up-regulation
CAMK_PKD_PRKD1_ST	P02686	MBP	Q15139	PRKD1	S141	G145E	145	Missense	distal	4	no	6.683	6.664	EPSD	GDSC	4.507	Down-regulation
CAMK_PKD_PRKD1_ST	P02686	MBP	Q15139	PRKD1	S146	G145E	145	Missense	proximal	-1	no	6.250	6.404	EPSD	GDSC	4.507	Up-regulation
CAMK_PKD_PRKD1_ST	P02686	MBP	Q15139	PRKD1	S146	T151I	151	Missense	distal	5	no	6.250	6.242	EPSD	GDSC	4.507	Down-regulation
CAMK_PKD_PRKD1_ST	P02686	MBP	Q15139	PRKD1	T154	T151I	151	Missense	distal	-3	no	4.763	3.190	EPSD	GDSC	4.507	Loss
CAMK_PKD_PRKD1_ST	P23528	CFL1	Q15139	PRKD1	S113	L111R	111	Missense	proximal	-2	no	2.990	6.098	EPSD	GDSC;CCLE	4.507	Gain
CAMK_PKD_PRKD1_ST	P22059	OSBP	Q15139	PRKD1	T174	W172S	172	Missense	proximal	-2	no	4.552	6.170	EPSD	GDSC;CCLE	4.507	Up-regulation
CAMK_PKD_PRKD1_ST	P50552	VASP	Q15139	PRKD1	S157	R155Q	155	Missense	proximal	-2	no	9.857	7.890	PhosphoSitePlus;EPSD	GDSC	4.507	Down-regulation
CAMK_PKD_PRKD1_ST	P50552	VASP	Q15139	PRKD1	S157	N158H	158	Missense	proximal	1	no	9.857	9.858	PhosphoSitePlus;EPSD	GDSC	4.507	Up-regulation
CAMK_PKD_PRKD1_ST	Q92918	MAP4K1	Q15139	PRKD1	S368	Q372*	372	Missense	distal	4	no	7.175	7.191	EPSD	GDSC	4.507	Up-regulation
CAMK_PKD_PRKD1_ST	Q92918	MAP4K1	Q15139	PRKD1	S430	V426F	426	Missense	distal	-4	no	8.323	8.322	EPSD	GDSC;CCLE	4.507	Down-regulation
CAMK_PKD_PRKD1_ST	Q92918	MAP4K1	Q15139	PRKD1	S430	R427Q	427	Missense	distal	-3	no	8.323	3.911	EPSD	GDSC	4.507	Loss
CAMK_PKD_PRKD1_ST	O00206	TLR4	Q15139	PRKD1	S790	N792S	792	Missense	proximal	2	no	8.857	8.941	PhosphoSitePlus	GDSC	4.507	Up-regulation
CAMK_PKD_PRKD1_ST	O00206	TLR4	Q15139	PRKD1	S800	W797*	797	Missense	distal	-3	no	3.732	4.713	EPSD	GDSC	4.507	Gain
CAMK_PKD_PRKD1_ST	O00206	TLR4	Q15139	PRKD1	S800	W797C	797	Missense	distal	-3	no	3.732	5.008	EPSD	GDSC;CCLE	4.507	Gain
CAMK_PKD_PRKD1_ST	P04792	HSPB1	Q15139	PRKD1	S43	R37G	37	Missense	distal	-6	no	4.571	4.532	EPSD	GDSC;CCLE	4.507	Down-regulation
CAMK_PKD_PRKD1_ST	P04792	HSPB1	Q15139	PRKD1	S158	S155P	155	Missense	distal	-3	no	4.483	5.003	EPSD	GDSC;CCLE	4.507	Gain
TK_PDGFR_KIT_Y	P10721	KIT	P10721	KIT	Y578	K581N	581	Missense	distal	3	no	1.744	1.771	EPSD	GDSC;CCLE	1.639	Up-regulation
TK_PDGFR_KIT_Y	P10721	KIT	P10721	KIT	Y703	A701S	701	Missense	proximal	-2	no	3.477	3.482	EPSD;PhosphoSitePlus	GDSC;CCLE	1.639	Up-regulation
TK_PDGFR_KIT_Y	Q9GZY6	LAT2	P10721	KIT	Y110	M116V	116	Missense	distal	6	no	4.234	4.266	PhosphoSitePlus;EPSD	GDSC	1.639	Up-regulation
TK_PDGFR_KIT_Y	Q9GZY6	LAT2	P10721	KIT	Y110	I111V	111	Missense	proximal	1	no	4.234	4.350	PhosphoSitePlus;EPSD	GDSC	1.639	Up-regulation
TK_PDGFR_KIT_Y	Q9GZY6	LAT2	P10721	KIT	Y118	M116V	116	Missense	proximal	-2	no	3.690	3.688	EPSD;PhosphoSitePlus	GDSC	1.639	Down-regulation
TK_PDGFR_KIT_Y	Q9GZY6	LAT2	P10721	KIT	Y118	I111V	111	Missense	distal	-7	no	3.690	3.533	EPSD;PhosphoSitePlus	GDSC	1.639	Down-regulation
Other_PEK_PKR_EIF2AK2_ST	P19525	EIF2AK2	P19525	EIF2AK2	S83	T90A	90	Missense	distal	7	no	102.539	99.110	EPSD;PhosphoSitePlus	GDSC;CCLE	66.906	Down-regulation
Other_PEK_PKR_EIF2AK2_ST	P19525	EIF2AK2	P19525	EIF2AK2	T88	T90A	90	Missense	proximal	2	no	116.907	116.594	EPSD;PhosphoSitePlus	GDSC;CCLE	66.906	Down-regulation
Other_PEK_PKR_EIF2AK2_ST	P19525	EIF2AK2	P19525	EIF2AK2	T89	T90A	90	Missense	proximal	1	no	104.941	107.201	EPSD;PhosphoSitePlus	GDSC;CCLE	66.906	Up-regulation
Other_PEK_PKR_EIF2AK2_ST	P19525	EIF2AK2	P19525	EIF2AK2	T90	T90A	90	Missense	central	0	yes	96.407	0.000	EPSD;PhosphoSitePlus	GDSC;CCLE	66.906	Loss
Other_PEK_PKR_EIF2AK2_ST	P05198	EIF2S1	P19525	EIF2AK2	S49	R54W	54	Missense	distal	5	no	99.991	98.399	PhosphoSitePlus;EPSD	GDSC;CCLE	66.906	Down-regulation
Other_PEK_PKR_EIF2AK2_ST	P05198	EIF2S1	P19525	EIF2AK2	S52	R54W	54	Missense	proximal	2	no	109.481	109.393	EPSD;PhosphoSitePlus	GDSC;CCLE	66.906	Down-regulation
Other_PEK_PKR_EIF2AK2_ST	P10636	MAPT	P19525	EIF2AK2	T123	E125G	125	Missense	proximal	2	no	83.137	83.372	EPSD	GDSC	66.906	Up-regulation
Other_PEK_PKR_EIF2AK2_ST	P10636	MAPT	P19525	EIF2AK2	S637	V635I	635	Missense	proximal	-2	no	71.789	72.782	EPSD	GDSC	66.906	Up-regulation
Other_PEK_PKR_EIF2AK2_ST	P04637	TP53	P19525	EIF2AK2	S99	S94*	94	Missense	distal	-5	no	65.275	67.130	EPSD	GDSC	66.906	Gain
Other_PEK_PKR_EIF2AK2_ST	P04637	TP53	P19525	EIF2AK2	S149	Q144*	144	Missense	distal	-5	no	69.762	68.547	EPSD	GDSC	66.906	Down-regulation
Other_PEK_PKR_EIF2AK2_ST	P04637	TP53	P19525	EIF2AK2	S149	W146*	146	Missense	distal	-3	no	69.762	66.382	EPSD	GDSC	66.906	Loss
Other_PEK_PKR_EIF2AK2_ST	P04637	TP53	P19525	EIF2AK2	S314	Q317*	317	Missense	distal	3	no	66.176	68.430	EPSD	GDSC	66.906	Gain
Other_PEK_PKR_EIF2AK2_ST	P04637	TP53	P19525	EIF2AK2	S314	K319*	319	Missense	distal	5	no	66.176	67.957	EPSD	GDSC	66.906	Gain
TK_Eph_EPHA2_Y	P29317	EPHA2	P29317	EPHA2	Y594	D596E	596	Missense	proximal	2	no	3.437	3.433	EPSD;PhosphoSitePlus	GDSC;CCLE	1.229	Down-regulation
TK_Eph_EPHA2_Y	P29317	EPHA2	P29317	EPHA2	Y694	D701E	701	Missense	distal	7	no	2.212	2.157	EPSD;PhosphoSitePlus	GDSC	1.229	Down-regulation
TK_Eph_EPHA2_Y	P29317	EPHA2	P29317	EPHA2	Y694	N697I	697	Missense	distal	3	no	2.212	2.240	EPSD;PhosphoSitePlus	GDSC	1.229	Up-regulation
TK_Eph_EPHA2_Y	P29317	EPHA2	P29317	EPHA2	Y960	A959T	959	Missense	proximal	-1	no	1.938	2.133	EPSD;PhosphoSitePlus	GDSC	1.229	Up-regulation
CAMK_CAMKL_LKB_STK11_ST	P60484	PTEN	Q15831	STK11	T398	Q399*	399	Missense	proximal	1	no	16.887	16.919	EPSD	GDSC	16.403	Up-regulation
CAMK_CAMKL_LKB_STK11_ST	Q7RTN6	STRADA	Q15831	STK11	S52	S47*	47	Missense	distal	-5	no	22.120	23.552	EPSD	GDSC	16.403	Up-regulation
CAMK_CAMKL_LKB_STK11_ST	Q7RTN6	STRADA	Q15831	STK11	T329	T331P	331	Missense	proximal	2	no	35.152	34.780	PhosphoSitePlus;EPSD	GDSC	16.403	Down-regulation
CAMK_CAMKL_LKB_STK11_ST	Q13485	SMAD4	Q15831	STK11	T77	T77P	77	Missense	central	0	yes	32.038	0.000	PhosphoSitePlus	GDSC	16.403	Loss
CAMK_CAMKL_LKB_STK11_ST	Q13485	SMAD4	Q15831	STK11	S171	E175K	175	Missense	distal	4	no	23.775	25.398	EPSD	GDSC;CCLE	16.403	Up-regulation
CAMK_CAMKL_LKB_STK11_ST	P27448	MARK3	Q15831	STK11	T278	T278I	278	Missense	central	0	yes	16.513	0.000	EPSD	GDSC;CCLE	16.403	Loss
CAMK_CAMKL_LKB_STK11_ST	P27448	MARK3	Q15831	STK11	T497	S499A	499	Missense	proximal	2	no	28.512	26.885	EPSD	GDSC;CCLE	16.403	Down-regulation
CAMK_CAMKL_LKB_STK11_ST	P27448	MARK3	Q15831	STK11	T514	A516T	516	Missense	proximal	2	no	25.152	27.297	EPSD	GDSC;CCLE	16.403	Up-regulation
CAMK_CAMKL_LKB_STK11_ST	P27448	MARK3	Q15831	STK11	T515	A516T	516	Missense	proximal	1	no	21.939	21.957	EPSD	GDSC;CCLE	16.403	Up-regulation
CAMK_CAMKL_LKB_STK11_ST	P27448	MARK3	Q15831	STK11	T574	P581L	581	Missense	distal	7	no	19.679	18.313	EPSD	GDSC;CCLE	16.403	Down-regulation
CAMK_CAMKL_LKB_STK11_ST	P27448	MARK3	Q15831	STK11	T574	G579A	579	Missense	distal	5	no	19.679	19.455	EPSD	GDSC	16.403	Down-regulation
CAMK_CAMKL_LKB_STK11_ST	P27448	MARK3	Q15831	STK11	T574	R572W	572	Missense	proximal	-2	no	19.679	17.663	EPSD	GDSC;CCLE	16.403	Down-regulation
CAMK_CAMKL_LKB_STK11_ST	P27448	MARK3	Q15831	STK11	T627	E630D	630	Missense	distal	3	no	13.500	17.785	EPSD	GDSC;CCLE	16.403	Gain
CAMK_CAMKL_LKB_STK11_ST	P27448	MARK3	Q15831	STK11	S663	S663I	663	Missense	central	0	yes	20.973	0.000	EPSD	GDSC;CCLE	16.403	Loss
CAMK_CAMKL_LKB_STK11_ST	Q9H093	NUAK2	Q15831	STK11	T208	T208A	208	Missense	central	0	yes	57.217	0.000	PhosphoSitePlus	GDSC;CCLE	16.403	Loss
CAMK_CAMKL_LKB_STK11_ST	Q9H093	NUAK2	Q15831	STK11	T519	T520A	520	Missense	proximal	1	no	24.260	24.242	EPSD	GDSC	16.403	Down-regulation
CAMK_CAMKL_LKB_STK11_ST	Q9H093	NUAK2	Q15831	STK11	T519	E526K	526	Missense	distal	7	no	24.260	23.560	EPSD	GDSC;CCLE	16.403	Down-regulation
CAMK_CAMKL_LKB_STK11_ST	Q8TDC3	BRSK1	Q15831	STK11	T531	P537L	537	Missense	distal	6	no	24.346	22.628	EPSD	GDSC	16.403	Down-regulation
CAMK_CAMKL_LKB_STK11_ST	Q15831	STK11	Q15831	STK11	T336	W332*	332	Missense	distal	-4	no	31.420	32.199	EPSD;PhosphoSitePlus	GDSC	16.403	Up-regulation
CAMK_CAMKL_LKB_STK11_ST	P57059	SIK1	Q15831	STK11	S545	S540L	540	Missense	distal	-5	no	17.198	16.138	EPSD	GDSC	16.403	Loss
CAMK_CAMKL_LKB_STK11_ST	O14744	PRMT5	Q15831	STK11	T185	W189*	189	Missense	distal	4	no	22.752	23.922	EPSD	GDSC	16.403	Up-regulation
CAMK_CAMKL_LKB_STK11_ST	O14744	PRMT5	Q15831	STK11	T194	W189*	189	Missense	distal	-5	no	16.757	17.329	EPSD	GDSC	16.403	Up-regulation
CAMK_CAMKL_LKB_STK11_ST	O60285	NUAK1	Q15831	STK11	T211	S215I	215	Missense	distal	4	no	57.079	57.429	PhosphoSitePlus	GDSC;CCLE	16.403	Up-regulation
CAMK_CAMKL_LKB_STK11_ST	O60285	NUAK1	Q15831	STK11	S267	E272K	272	Missense	distal	5	no	20.927	19.954	EPSD	GDSC;CCLE	16.403	Down-regulation
CAMK_CAMKL_LKB_STK11_ST	O60285	NUAK1	Q15831	STK11	S267	R271Q	271	Missense	distal	4	no	20.927	20.976	EPSD	GDSC;CCLE	16.403	Up-regulation
CAMK_CAMKL_LKB_STK11_ST	O60285	NUAK1	Q15831	STK11	S550	G555S	555	Missense	distal	5	no	17.108	17.200	EPSD	GDSC;CCLE	16.403	Up-regulation
CAMK_CAMKL_LKB_STK11_ST	Q14680	MELK	Q15831	STK11	S431	Y438*	438	Missense	distal	7	no	22.659	22.947	EPSD	GDSC	16.403	Up-regulation
CAMK_CAMKL_LKB_STK11_ST	Q14680	MELK	Q15831	STK11	T459	E456G	456	Missense	distal	-3	no	18.552	18.365	EPSD	GDSC;CCLE	16.403	Down-regulation
CAMK_CAMKL_LKB_STK11_ST	Q14680	MELK	Q15831	STK11	T459	I457K	457	Missense	proximal	-2	no	18.552	19.984	EPSD	GDSC;CCLE	16.403	Up-regulation
CAMK_CAMKL_LKB_STK11_ST	Q14680	MELK	Q15831	STK11	T459	L458F	458	Missense	proximal	-1	no	18.552	18.241	EPSD	GDSC;CCLE	16.403	Down-regulation
CAMK_CAMKL_LKB_STK11_ST	Q14680	MELK	Q15831	STK11	T566	H560Y	560	Missense	distal	-6	no	18.093	18.114	EPSD	GDSC;CCLE	16.403	Up-regulation
CAMK_CAMKL_LKB_STK11_ST	Q96L34	MARK4	Q15831	STK11	S458	G463V	463	Missense	distal	5	no	18.884	18.689	EPSD	GDSC;CCLE	16.403	Down-regulation
CAMK_CAMKL_LKB_STK11_ST	Q96L34	MARK4	Q15831	STK11	S458	A457V	457	Missense	proximal	-1	no	18.884	18.697	EPSD	GDSC;CCLE	16.403	Down-regulation
CAMK_CAMKL_LKB_STK11_ST	Q96L34	MARK4	Q15831	STK11	T497	R490Q	490	Missense	distal	-7	no	20.753	21.020	EPSD	GDSC	16.403	Up-regulation
CAMK_CAMKL_LKB_STK11_ST	P38936	CDKN1A	Q15831	STK11	T80	P79H	79	Missense	proximal	-1	no	18.169	18.615	PhosphoSitePlus	GDSC;CCLE	16.403	Up-regulation
CAMK_CAMKL_LKB_STK11_ST	P38936	CDKN1A	Q15831	STK11	T80	P79L	79	Missense	proximal	-1	no	18.169	19.067	PhosphoSitePlus	GDSC;CCLE	16.403	Up-regulation
CAMK_CAMKL_LKB_STK11_ST	P38936	CDKN1A	Q15831	STK11	S114	L119R	119	Missense	distal	5	no	20.210	19.897	EPSD	GDSC;CCLE	16.403	Down-regulation
CAMK_CAMKL_LKB_STK11_ST	Q8IWQ3	BRSK2	Q15831	STK11	T613	S616*	616	Missense	distal	3	no	10.075	17.598	EPSD	GDSC	16.403	Gain
CAMK_CAMKL_LKB_STK11_ST	Q9P0L2	MARK1	Q15831	STK11	T215	Y222H	222	Missense	distal	7	no	61.517	61.205	PhosphoSitePlus	GDSC;CCLE	16.403	Down-regulation
CAMK_CAMKL_LKB_STK11_ST	Q9P0L2	MARK1	Q15831	STK11	S219	Y222H	222	Missense	distal	3	no	22.096	20.895	EPSD	GDSC;CCLE	16.403	Down-regulation
CAMK_CAMKL_LKB_STK11_ST	Q9P0L2	MARK1	Q15831	STK11	T613	E617G	617	Missense	distal	4	no	21.439	21.600	EPSD	GDSC;CCLE	16.403	Up-regulation
CAMK_CAMKL_LKB_STK11_ST	P46937	YAP1	Q15831	STK11	S163	R161*	161	Missense	proximal	-2	no	16.377	16.644	EPSD	GDSC	16.403	Gain
CAMK_CAMKL_LKB_STK11_ST	P46937	YAP1	Q15831	STK11	S350	A347S	347	Missense	distal	-3	no	28.145	28.248	EPSD	GDSC	16.403	Up-regulation
CAMK_CAMKL_LKB_STK11_ST	P46937	YAP1	Q15831	STK11	S350	Q357P	357	Missense	distal	7	no	28.145	28.775	EPSD	GDSC	16.403	Up-regulation
CAMK_CAMKL_LKB_STK11_ST	P46937	YAP1	Q15831	STK11	S350	E356D	356	Missense	distal	6	no	28.145	28.527	EPSD	GDSC;CCLE	16.403	Up-regulation
CAMK_CAMKL_LKB_STK11_ST	P46937	YAP1	Q15831	STK11	T354	Q357P	357	Missense	distal	3	no	12.422	17.582	EPSD	GDSC	16.403	Gain
CAMK_CAMKL_LKB_STK11_ST	Q9H0K1	SIK2	Q15831	STK11	T175	S169T	169	Missense	distal	-6	no	60.719	60.668	PhosphoSitePlus	GDSC;CCLE	16.403	Down-regulation
CAMK_CAMKL_LKB_STK11_ST	Q9H0K1	SIK2	Q15831	STK11	T458	T458I	458	Missense	central	0	yes	19.538	0.000	EPSD	GDSC	16.403	Loss
CAMK_CAMKL_LKB_STK11_ST	Q9H0K1	SIK2	Q15831	STK11	T458	G460E	460	Missense	proximal	2	no	19.538	23.421	EPSD	GDSC;CCLE	16.403	Up-regulation
CAMK_CAMKL_MARK_MARK1_ST	P10636	MAPT	Q9P0L2	MARK1	T71	P78T	78	Missense	distal	7	no	0.253	0.251	EPSD	GDSC;CCLE	0.230	Down-regulation
CAMK_CAMKL_MARK_MARK1_ST	P10636	MAPT	Q9P0L2	MARK1	S228	R222H	222	Missense	distal	-6	no	0.334	0.335	EPSD	GDSC;CCLE	0.230	Up-regulation
CAMK_CAMKL_MARK_MARK1_ST	P10636	MAPT	Q9P0L2	MARK1	S637	V635I	635	Missense	proximal	-2	no	0.477	0.493	EPSD	GDSC	0.230	Up-regulation
CAMK_CAMKL_MARK_MARK1_ST	P10636	MAPT	Q9P0L2	MARK1	S641	V635I	635	Missense	distal	-6	no	0.498	0.431	EPSD	GDSC	0.230	Down-regulation
CAMK_CAMKL_MARK_MARK1_ST	P10636	MAPT	Q9P0L2	MARK1	S739	S739C	739	Missense	central	0	yes	0.354	0.000	EPSD	GDSC	0.230	Loss
CAMK_CAMKL_MARK_MARK1_ST	Q155Q3	DIXDC1	Q9P0L2	MARK1	S186	S185I	185	Missense	proximal	-1	no	0.218	0.230	EPSD	GDSC	0.230	Gain
CAMK_CAMKL_MARK_MARK1_ST	Q155Q3	DIXDC1	Q9P0L2	MARK1	S238	E240*	240	Missense	proximal	2	no	0.253	0.250	EPSD	GDSC	0.230	Down-regulation
Other_ULK_ULK_ULK3_ST	Q6PHR2	ULK3	Q6PHR2	ULK3	S300	Q296*	296	Missense	distal	-4	no	5.133	5.235	PhosphoSitePlus;EPSD	GDSC	1.534	Up-regulation
CAMK_CAMKL_MARK_MARK2_ST	P56524	HDAC4	Q7KZI7	MARK2	S3	P7L	7	Missense	distal	4	no	165.397	293.976	EPSD	GDSC	271.430	Gain
CAMK_CAMKL_MARK_MARK2_ST	P56524	HDAC4	Q7KZI7	MARK2	S5	P7L	7	Missense	proximal	2	no	306.977	288.582	EPSD	GDSC	271.430	Down-regulation
CAMK_CAMKL_MARK_MARK2_ST	Q8TEW0	PARD3	Q7KZI7	MARK2	S144	P137S	137	Missense	distal	-7	no	396.547	396.493	EPSD;PhosphoSitePlus	GDSC;CCLE	271.430	Down-regulation
CAMK_CAMKL_MARK_MARK2_ST	Q8TEW0	PARD3	Q7KZI7	MARK2	S174	G178D	178	Missense	distal	4	no	283.019	257.957	EPSD	GDSC;CCLE	271.430	Loss
CAMK_CAMKL_MARK_MARK2_ST	Q8TEW0	PARD3	Q7KZI7	MARK2	S174	T176A	176	Missense	proximal	2	no	283.019	274.205	EPSD	GDSC	271.430	Down-regulation
CAMK_CAMKL_MARK_MARK2_ST	Q8TEW0	PARD3	Q7KZI7	MARK2	S174	R172H	172	Missense	proximal	-2	no	283.019	282.788	EPSD	GDSC;CCLE	271.430	Down-regulation
CAMK_CAMKL_MARK_MARK2_ST	Q8TEW0	PARD3	Q7KZI7	MARK2	T175	G178D	178	Missense	distal	3	no	276.209	332.948	EPSD	GDSC;CCLE	271.430	Up-regulation
CAMK_CAMKL_MARK_MARK2_ST	Q8TEW0	PARD3	Q7KZI7	MARK2	T175	T176A	176	Missense	proximal	1	no	276.209	277.992	EPSD	GDSC	271.430	Up-regulation
CAMK_CAMKL_MARK_MARK2_ST	Q8TEW0	PARD3	Q7KZI7	MARK2	T175	R172H	172	Missense	distal	-3	no	276.209	253.230	EPSD	GDSC;CCLE	271.430	Loss
CAMK_CAMKL_MARK_MARK2_ST	Q8TEW0	PARD3	Q7KZI7	MARK2	S201	R204L	204	Missense	distal	3	no	277.002	289.783	EPSD	GDSC;CCLE	271.430	Up-regulation
CAMK_CAMKL_MARK_MARK2_ST	Q8TEW0	PARD3	Q7KZI7	MARK2	S396	T401R	401	Missense	distal	5	no	301.893	304.370	EPSD	GDSC;CCLE	271.430	Up-regulation
CAMK_CAMKL_MARK_MARK2_ST	Q8TEW0	PARD3	Q7KZI7	MARK2	T446	N452D	452	Missense	distal	6	no	295.550	290.733	EPSD	GDSC	271.430	Down-regulation
CAMK_CAMKL_MARK_MARK2_ST	Q8TEW0	PARD3	Q7KZI7	MARK2	T453	G457S	457	Missense	distal	4	no	281.736	194.074	EPSD	GDSC;CCLE	271.430	Loss
CAMK_CAMKL_MARK_MARK2_ST	Q8TEW0	PARD3	Q7KZI7	MARK2	T453	N452D	452	Missense	proximal	-1	no	281.736	281.542	EPSD	GDSC	271.430	Down-regulation
CAMK_CAMKL_MARK_MARK2_ST	Q8TEW0	PARD3	Q7KZI7	MARK2	T468	I462V	462	Missense	distal	-6	no	273.513	273.505	EPSD	GDSC;CCLE	271.430	Down-regulation
CAMK_CAMKL_MARK_MARK2_ST	Q8TEW0	PARD3	Q7KZI7	MARK2	S523	V520L	520	Missense	distal	-3	no	246.357	280.113	EPSD	GDSC;CCLE	271.430	Gain
CAMK_CAMKL_MARK_MARK2_ST	Q8TEW0	PARD3	Q7KZI7	MARK2	S667	T661I	661	Missense	distal	-6	no	337.841	338.053	EPSD	GDSC;CCLE	271.430	Up-regulation
CAMK_CAMKL_MARK_MARK2_ST	Q8TEW0	PARD3	Q7KZI7	MARK2	S807	P810L	810	Missense	distal	3	no	312.349	312.978	EPSD	GDSC;CCLE	271.430	Up-regulation
CAMK_CAMKL_MARK_MARK2_ST	Q8TEW0	PARD3	Q7KZI7	MARK2	S809	P810L	810	Missense	proximal	1	no	278.874	285.645	EPSD	GDSC;CCLE	271.430	Up-regulation
CAMK_CAMKL_MARK_MARK2_ST	Q8TEW0	PARD3	Q7KZI7	MARK2	S1116	G1120R	1120	Missense	distal	4	no	320.292	259.936	EPSD	GDSC;CCLE	271.430	Loss
CAMK_CAMKL_MARK_MARK2_ST	Q8TEW0	PARD3	Q7KZI7	MARK2	T1347	E1349K	1349	Missense	proximal	2	no	286.323	262.957	EPSD	GDSC;CCLE	271.430	Loss
CAMK_CAMKL_MARK_MARK2_ST	Q92974	ARHGEF2	Q7KZI7	MARK2	S137	R141H	141	Missense	distal	4	no	240.812	281.614	EPSD	GDSC	271.430	Gain
CAMK_CAMKL_MARK_MARK2_ST	Q92974	ARHGEF2	Q7KZI7	MARK2	S142	R141H	141	Missense	proximal	-1	no	302.986	308.108	EPSD	GDSC	271.430	Up-regulation
CAMK_CAMKL_MARK_MARK2_ST	Q92974	ARHGEF2	Q7KZI7	MARK2	S143	R141H	141	Missense	proximal	-2	no	344.445	344.214	EPSD;PhosphoSitePlus	GDSC	271.430	Down-regulation
CAMK_CAMKL_MARK_MARK2_ST	P10636	MAPT	Q7KZI7	MARK2	T17	T17M	17	Missense	central	0	yes	321.150	0.000	EPSD	GDSC	271.430	Loss
CAMK_CAMKL_MARK_MARK2_ST	P10636	MAPT	Q7KZI7	MARK2	S214	V218G	218	Missense	distal	4	no	313.338	338.552	EPSD	GDSC	271.430	Up-regulation
CAMK_CAMKL_MARK_MARK2_ST	P10636	MAPT	Q7KZI7	MARK2	S641	V635I	635	Missense	distal	-6	no	372.616	372.623	EPSD	GDSC	271.430	Up-regulation
CAMK_CAMKL_MARK_MARK2_ST	P10636	MAPT	Q7KZI7	MARK2	S733	S739C	739	Missense	distal	6	no	275.861	281.164	EPSD	GDSC	271.430	Up-regulation
CAMK_CAMKL_MARK_MARK2_ST	Q9NQT8	KIF13B	Q7KZI7	MARK2	S1381	S1376N	1376	Missense	distal	-5	no	362.657	382.664	EPSD;PhosphoSitePlus	GDSC;CCLE	271.430	Up-regulation
CAMK_CAMKL_MARK_MARK2_ST	Q9NQT8	KIF13B	Q7KZI7	MARK2	S1381	S1376R	1376	Missense	distal	-5	no	362.657	370.307	EPSD;PhosphoSitePlus	GDSC;CCLE	271.430	Up-regulation
CAMK_CAMKL_MARK_MARK2_ST	Q9NQT8	KIF13B	Q7KZI7	MARK2	S1382	S1376N	1376	Missense	distal	-6	no	295.086	296.513	EPSD	GDSC;CCLE	271.430	Up-regulation
CAMK_CAMKL_MARK_MARK2_ST	Q9NQT8	KIF13B	Q7KZI7	MARK2	S1382	S1376R	1376	Missense	distal	-6	no	295.086	295.021	EPSD	GDSC;CCLE	271.430	Down-regulation
CAMK_CAMKL_MARK_MARK2_ST	Q9NQT8	KIF13B	Q7KZI7	MARK2	S1398	K1405N	1405	Missense	distal	7	no	302.139	306.898	EPSD	GDSC	271.430	Up-regulation
CAMK_CAMKL_MARK_MARK2_ST	Q9NQT8	KIF13B	Q7KZI7	MARK2	S1410	K1405N	1405	Missense	distal	-5	no	349.208	355.648	PhosphoSitePlus;EPSD	GDSC	271.430	Up-regulation
CAMK_CAMKL_MARK_MARK2_ST	Q7L804	RAB11FIP2	Q7KZI7	MARK2	S150	L154I	154	Missense	distal	4	no	287.118	263.030	EPSD	GDSC;CCLE	271.430	Loss
CAMK_CAMKL_MARK_MARK2_ST	Q7L804	RAB11FIP2	Q7KZI7	MARK2	S227	R221*	221	Missense	distal	-6	no	390.699	389.354	PhosphoSitePlus	GDSC	271.430	Down-regulation
CAMK_CAMKL_MARK_MARK2_ST	Q7L804	RAB11FIP2	Q7KZI7	MARK2	S227	S229P	229	Missense	proximal	2	no	390.699	375.975	PhosphoSitePlus	GDSC;CCLE	271.430	Down-regulation
CAMK_CAMKL_MARK_MARK2_ST	Q7L804	RAB11FIP2	Q7KZI7	MARK2	S227	L222F	222	Missense	distal	-5	no	390.699	388.050	PhosphoSitePlus	GDSC	271.430	Down-regulation
CAMK_CAMKL_MARK_MARK2_ST	Q7L804	RAB11FIP2	Q7KZI7	MARK2	S380	D385G	385	Missense	distal	5	no	300.125	283.560	EPSD	GDSC;CCLE	271.430	Down-regulation
CAMK_CAMKL_MARK_MARK2_ST	Q7L804	RAB11FIP2	Q7KZI7	MARK2	S382	D385G	385	Missense	distal	3	no	340.659	283.920	EPSD	GDSC;CCLE	271.430	Down-regulation
CAMK_CAMKL_MARK_MARK2_ST	Q7L804	RAB11FIP2	Q7KZI7	MARK2	S388	D385G	385	Missense	distal	-3	no	262.445	305.454	EPSD	GDSC;CCLE	271.430	Gain
CAMK_CAMKL_MARK_MARK2_ST	Q99689	FEZ1	Q7KZI7	MARK2	S298	S298N	298	Missense	central	0	yes	280.634	0.000	EPSD	GDSC;CCLE	271.430	Loss
CAMK_CAMKL_MARK_MARK2_ST	Q9UQB8	BAIAP2	Q7KZI7	MARK2	S4	S4F	4	Missense	central	0	yes	301.374	0.000	EPSD	GDSC	271.430	Loss
CAMK_CAMKL_MARK_MARK2_ST	Q9UQB8	BAIAP2	Q7KZI7	MARK2	S6	S4F	4	Missense	proximal	-2	no	318.611	316.460	EPSD	GDSC	271.430	Down-regulation
CAMK_CAMKL_MARK_MARK2_ST	Q9UQB8	BAIAP2	Q7KZI7	MARK2	T303	Y310F	310	Missense	distal	7	no	293.838	297.769	EPSD	GDSC;CCLE	271.430	Up-regulation
CAMK_CAMKL_MARK_MARK2_ST	Q9UQB8	BAIAP2	Q7KZI7	MARK2	T355	S352G	352	Missense	distal	-3	no	286.952	309.172	EPSD	GDSC;CCLE	271.430	Up-regulation
CAMK_CAMKL_MARK_MARK2_ST	Q9UQB8	BAIAP2	Q7KZI7	MARK2	T355	K359R	359	Missense	distal	4	no	286.952	265.842	EPSD	GDSC;CCLE	271.430	Loss
CAMK_CAMKL_MARK_MARK2_ST	Q9UQB8	BAIAP2	Q7KZI7	MARK2	T355	T356I	356	Missense	proximal	1	no	286.952	294.202	EPSD	GDSC	271.430	Up-regulation
CAMK_CAMKL_MARK_MARK2_ST	Q9UQB8	BAIAP2	Q7KZI7	MARK2	T356	S352G	352	Missense	distal	-4	no	278.310	276.070	EPSD	GDSC;CCLE	271.430	Down-regulation
CAMK_CAMKL_MARK_MARK2_ST	Q9UQB8	BAIAP2	Q7KZI7	MARK2	T356	K359R	359	Missense	distal	3	no	278.310	283.609	EPSD	GDSC;CCLE	271.430	Up-regulation
CAMK_CAMKL_MARK_MARK2_ST	Q9UQB8	BAIAP2	Q7KZI7	MARK2	T356	T356I	356	Missense	central	0	yes	278.310	0.000	EPSD	GDSC	271.430	Loss
CAMK_CAMKL_MARK_MARK2_ST	Q9UQB8	BAIAP2	Q7KZI7	MARK2	S364	K359R	359	Missense	distal	-5	no	305.903	299.986	EPSD	GDSC;CCLE	271.430	Down-regulation
CAMK_CAMKL_MARK_MARK2_ST	Q9UQB8	BAIAP2	Q7KZI7	MARK2	S366	K359R	359	Missense	distal	-7	no	364.709	364.648	PhosphoSitePlus	GDSC;CCLE	271.430	Down-regulation
CAMK_CAMKL_MARK_MARK2_ST	Q9BXM7	PINK1	Q7KZI7	MARK2	S402	P399L	399	Missense	distal	-3	no	237.148	272.620	EPSD	GDSC;CCLE	271.430	Gain
CAMK_CAMKL_MARK_MARK2_ST	P46939	UTRN	Q7KZI7	MARK2	S623	R627G	627	Missense	distal	4	no	255.049	315.406	EPSD	GDSC;CCLE	271.430	Gain
CAMK_CAMKL_MARK_MARK2_ST	P46939	UTRN	Q7KZI7	MARK2	S631	Q626R	626	Missense	distal	-5	no	271.051	281.943	EPSD	GDSC;CCLE	271.430	Gain
CAMK_CAMKL_MARK_MARK2_ST	P46939	UTRN	Q7KZI7	MARK2	S933	S933Y	933	Missense	central	0	yes	296.215	0.000	EPSD	GDSC;CCLE	271.430	Loss
CAMK_CAMKL_MARK_MARK2_ST	P46939	UTRN	Q7KZI7	MARK2	S1486	K1483T	1483	Missense	distal	-3	no	289.084	203.489	EPSD	GDSC	271.430	Loss
CAMK_CAMKL_MARK_MARK2_ST	P46939	UTRN	Q7KZI7	MARK2	S1746	H1743R	1743	Missense	distal	-3	no	282.605	305.585	EPSD	GDSC	271.430	Up-regulation
CAMK_CAMKL_MARK_MARK2_ST	P46939	UTRN	Q7KZI7	MARK2	S1795	S1795P	1795	Missense	central	0	yes	293.587	0.000	EPSD	GDSC;CCLE	271.430	Loss
CAMK_CAMKL_MARK_MARK2_ST	P46939	UTRN	Q7KZI7	MARK2	S2211	I2215V	2215	Missense	distal	4	no	324.528	325.528	EPSD	GDSC	271.430	Up-regulation
CAMK_CAMKL_MARK_MARK2_ST	P46939	UTRN	Q7KZI7	MARK2	S2211	S2213L	2213	Missense	proximal	2	no	324.528	291.409	EPSD	GDSC	271.430	Down-regulation
CAMK_CAMKL_MARK_MARK2_ST	P46939	UTRN	Q7KZI7	MARK2	S2211	S2211P	2211	Missense	central	0	yes	324.528	0.000	EPSD	GDSC	271.430	Loss
CAMK_CAMKL_MARK_MARK2_ST	P46939	UTRN	Q7KZI7	MARK2	S2666	R2662S	2662	Missense	distal	-4	no	315.156	315.554	EPSD	GDSC;CCLE	271.430	Up-regulation
CAMK_CAMKL_MARK_MARK2_ST	P46939	UTRN	Q7KZI7	MARK2	S2666	W2672L	2672	Missense	distal	6	no	315.156	335.972	EPSD	GDSC;CCLE	271.430	Up-regulation
CAMK_CAMKL_MARK_MARK2_ST	P46939	UTRN	Q7KZI7	MARK2	S2760	Q2758*	2758	Missense	proximal	-2	no	284.984	284.467	EPSD	GDSC	271.430	Down-regulation
CAMK_CAMKL_MARK_MARK2_ST	P46939	UTRN	Q7KZI7	MARK2	S2851	S2851C	2851	Missense	central	0	yes	305.310	0.000	EPSD	GDSC;CCLE	271.430	Loss
CAMK_CAMKL_MARK_MARK2_ST	Q9UQL6	HDAC5	Q7KZI7	MARK2	S3	S7L	7	Missense	distal	4	no	211.136	296.670	EPSD	GDSC	271.430	Gain
CAMK_CAMKL_MARK_MARK2_ST	Q6WKZ4	RAB11FIP1	Q7KZI7	MARK2	S202	D201G	201	Missense	proximal	-1	no	268.358	273.848	EPSD	GDSC;CCLE	271.430	Gain
CAMK_CAMKL_MARK_MARK2_ST	Q6WKZ4	RAB11FIP1	Q7KZI7	MARK2	S222	Q227H	227	Missense	distal	5	no	289.228	295.020	EPSD	GDSC;CCLE	271.430	Up-regulation
CAMK_CAMKL_MARK_MARK2_ST	Q6WKZ4	RAB11FIP1	Q7KZI7	MARK2	S224	Q227H	227	Missense	distal	3	no	344.013	332.293	EPSD	GDSC;CCLE	271.430	Down-regulation
CAMK_CAMKL_MARK_MARK2_ST	Q6WKZ4	RAB11FIP1	Q7KZI7	MARK2	S234	Q227H	227	Missense	distal	-7	no	361.908	361.878	PhosphoSitePlus	GDSC;CCLE	271.430	Down-regulation
CAMK_CAMKL_MARK_MARK2_ST	Q6WKZ4	RAB11FIP1	Q7KZI7	MARK2	S268	M273K	273	Missense	distal	5	no	282.540	291.864	EPSD	GDSC;CCLE	271.430	Up-regulation
CAMK_CAMKL_MARK_MARK2_ST	Q6WKZ4	RAB11FIP1	Q7KZI7	MARK2	T278	M273K	273	Missense	distal	-5	no	283.416	292.281	EPSD	GDSC;CCLE	271.430	Up-regulation
CAMK_CAMKL_MARK_MARK2_ST	Q6WKZ4	RAB11FIP1	Q7KZI7	MARK2	T278	A279E	279	Missense	proximal	1	no	283.416	282.586	EPSD	GDSC	271.430	Down-regulation
CAMK_CAMKL_MARK_MARK2_ST	Q6WKZ4	RAB11FIP1	Q7KZI7	MARK2	S280	M273K	273	Missense	distal	-7	no	365.593	365.522	EPSD	GDSC;CCLE	271.430	Down-regulation
CAMK_CAMKL_MARK_MARK2_ST	Q6WKZ4	RAB11FIP1	Q7KZI7	MARK2	S280	A279E	279	Missense	proximal	-1	no	365.593	365.042	EPSD	GDSC	271.430	Down-regulation
CAMK_CAMKL_MARK_MARK2_ST	Q6WKZ4	RAB11FIP1	Q7KZI7	MARK2	S343	P340L	340	Missense	distal	-3	no	304.388	339.860	EPSD	GDSC	271.430	Up-regulation
CAMK_CAMKL_MARK_MARK2_ST	Q6WKZ4	RAB11FIP1	Q7KZI7	MARK2	S1162	A1167T	1167	Missense	distal	5	no	266.361	278.471	EPSD	GDSC;CCLE	271.430	Gain
CMGC_CLK_CLK2_ST	P18031	PTPN1	P49760	CLK2	S203	K197E	197	Missense	distal	-6	no	0.004	0.005	EPSD	GDSC;CCLE	0.005	Gain
CMGC_CLK_CLK2_ST	P18031	PTPN1	P49760	CLK2	S203	G209R	209	Missense	distal	6	no	0.004	0.005	EPSD	GDSC;CCLE	0.005	Gain
AGC_SGK_SGK1_ST	O00213	APBB1	O00141	SGK1	T92	Q87K	87	Missense	distal	-5	no	9.998	13.606	EPSD	GDSC;CCLE	9.140	Up-regulation
AGC_SGK_SGK1_ST	O00213	APBB1	O00141	SGK1	S289	S287C	287	Missense	proximal	-2	no	10.163	10.035	EPSD	GDSC;CCLE	9.140	Down-regulation
AGC_SGK_SGK1_ST	O00213	APBB1	O00141	SGK1	S289	S292I	292	Missense	distal	3	no	10.163	9.676	EPSD	GDSC;CCLE	9.140	Down-regulation
AGC_SGK_SGK1_ST	O00213	APBB1	O00141	SGK1	S610	R605G	605	Missense	distal	-5	no	18.399	13.039	PhosphoSitePlus	GDSC	9.140	Down-regulation
AGC_SGK_SGK1_ST	Q96PU5	NEDD4L	O00141	SGK1	S340	A346T	346	Missense	distal	6	no	16.090	16.031	EPSD	GDSC;CCLE	9.140	Down-regulation
AGC_SGK_SGK1_ST	Q96PU5	NEDD4L	O00141	SGK1	S342	A346T	346	Missense	distal	4	no	16.913	16.852	PhosphoSitePlus;EPSD	GDSC;CCLE	9.140	Down-regulation
AGC_SGK_SGK1_ST	Q96PU5	NEDD4L	O00141	SGK1	S365	T369R	369	Missense	distal	4	no	10.437	10.429	EPSD	GDSC	9.140	Down-regulation
AGC_SGK_SGK1_ST	Q96PU5	NEDD4L	O00141	SGK1	T367	T369R	369	Missense	proximal	2	no	14.642	14.749	EPSD;PhosphoSitePlus	GDSC	9.140	Up-regulation
AGC_SGK_SGK1_ST	Q96PU5	NEDD4L	O00141	SGK1	S637	Y632C	632	Missense	distal	-5	no	11.349	9.603	EPSD	GDSC	9.140	Down-regulation
AGC_SGK_SGK1_ST	P49815	TSC2	O00141	SGK1	S981	R988C	988	Missense	distal	7	no	15.889	16.018	EPSD;PhosphoSitePlus	GDSC;CCLE	9.140	Up-regulation
AGC_SGK_SGK1_ST	P49815	TSC2	O00141	SGK1	S983	R988C	988	Missense	distal	5	no	11.799	11.782	EPSD	GDSC;CCLE	9.140	Down-regulation
AGC_SGK_SGK1_ST	P49815	TSC2	O00141	SGK1	T993	R988C	988	Missense	distal	-5	no	17.102	10.840	EPSD	GDSC;CCLE	9.140	Down-regulation
AGC_SGK_SGK1_ST	P49815	TSC2	O00141	SGK1	S1045	P1042R	1042	Missense	distal	-3	no	0.413	12.511	EPSD	GDSC;CCLE	9.140	Gain
AGC_SGK_SGK1_ST	P49815	TSC2	O00141	SGK1	T1271	L1266M	1266	Missense	distal	-5	no	15.277	12.117	EPSD	GDSC;CCLE	9.140	Down-regulation
AGC_SGK_SGK1_ST	O60343	TBC1D4	O00141	SGK1	S133	H131R	131	Missense	proximal	-2	no	9.772	10.209	EPSD	GDSC;CCLE	9.140	Up-regulation
AGC_SGK_SGK1_ST	O60343	TBC1D4	O00141	SGK1	S318	Q323P	323	Missense	distal	5	no	18.274	18.252	PhosphoSitePlus;EPSD	GDSC;CCLE	9.140	Down-regulation
AGC_SGK_SGK1_ST	O60343	TBC1D4	O00141	SGK1	S341	R337W	337	Missense	distal	-4	no	18.973	17.755	EPSD;PhosphoSitePlus	GDSC;CCLE	9.140	Down-regulation
AGC_SGK_SGK1_ST	O60343	TBC1D4	O00141	SGK1	S341	R336*	336	Missense	distal	-5	no	18.973	10.624	EPSD;PhosphoSitePlus	GDSC	9.140	Down-regulation
AGC_SGK_SGK1_ST	O60343	TBC1D4	O00141	SGK1	T568	K564N	564	Missense	distal	-4	no	14.705	14.313	EPSD;PhosphoSitePlus	GDSC;CCLE	9.140	Down-regulation
AGC_SGK_SGK1_ST	O60343	TBC1D4	O00141	SGK1	T568	K564R	564	Missense	distal	-4	no	14.705	14.524	EPSD;PhosphoSitePlus	GDSC	9.140	Down-regulation
AGC_SGK_SGK1_ST	O60343	TBC1D4	O00141	SGK1	S570	K564N	564	Missense	distal	-6	no	11.123	10.991	EPSD;PhosphoSitePlus	GDSC;CCLE	9.140	Down-regulation
AGC_SGK_SGK1_ST	O60343	TBC1D4	O00141	SGK1	S570	K564R	564	Missense	distal	-6	no	11.123	10.976	EPSD;PhosphoSitePlus	GDSC	9.140	Down-regulation
AGC_SGK_SGK1_ST	O60343	TBC1D4	O00141	SGK1	S771	R769Q	769	Missense	proximal	-2	no	10.734	10.281	EPSD	GDSC;CCLE	9.140	Down-regulation
AGC_SGK_SGK1_ST	O60343	TBC1D4	O00141	SGK1	S771	R769W	769	Missense	proximal	-2	no	10.734	9.980	EPSD	GDSC	9.140	Down-regulation
AGC_SGK_SGK1_ST	O60343	TBC1D4	O00141	SGK1	S1207	S1207N	1207	Missense	central	0	yes	15.589	0.000	EPSD	GDSC;CCLE	9.140	Loss
AGC_SGK_SGK1_ST	Q9UN36	NDRG2	O00141	SGK1	S346	R343W	343	Missense	distal	-3	no	14.496	4.801	EPSD;PhosphoSitePlus	GDSC;CCLE	9.140	Loss
AGC_SGK_SGK1_ST	Q9UN36	NDRG2	O00141	SGK1	S346	Q351*	351	Missense	distal	5	no	14.496	14.431	EPSD;PhosphoSitePlus	GDSC	9.140	Down-regulation
AGC_SGK_SGK1_ST	Q9UN36	NDRG2	O00141	SGK1	T348	R343W	343	Missense	distal	-5	no	19.728	12.070	PhosphoSitePlus;EPSD	GDSC;CCLE	9.140	Down-regulation
AGC_SGK_SGK1_ST	Q9UN36	NDRG2	O00141	SGK1	T348	Q351*	351	Missense	distal	3	no	19.728	19.293	PhosphoSitePlus;EPSD	GDSC	9.140	Down-regulation
AGC_SGK_SGK1_ST	Q9UN36	NDRG2	O00141	SGK1	S350	R343W	343	Missense	distal	-7	no	16.482	17.596	EPSD	GDSC;CCLE	9.140	Up-regulation
AGC_SGK_SGK1_ST	Q9UN36	NDRG2	O00141	SGK1	S350	Q351*	351	Missense	proximal	1	no	16.482	16.623	EPSD	GDSC	9.140	Up-regulation
AGC_SGK_SGK1_ST	Q9UN36	NDRG2	O00141	SGK1	S352	Q351*	351	Missense	proximal	-1	no	9.627	9.512	EPSD	GDSC	9.140	Down-regulation
AGC_SGK_SGK1_ST	P10636	MAPT	O00141	SGK1	S171	D177V	177	Missense	distal	6	no	12.821	12.655	EPSD	GDSC	9.140	Down-regulation
AGC_SGK_SGK1_ST	P10636	MAPT	O00141	SGK1	S214	V218G	218	Missense	distal	4	no	13.460	13.534	PhosphoSitePlus	GDSC	9.140	Up-regulation
AGC_SGK_SGK1_ST	P10636	MAPT	O00141	SGK1	S341	P340L	340	Missense	proximal	-1	no	9.968	10.071	EPSD	GDSC;CCLE	9.140	Up-regulation
AGC_SGK_SGK1_ST	P10636	MAPT	O00141	SGK1	S341	G339S	339	Missense	proximal	-2	no	9.968	10.418	EPSD	GDSC;CCLE	9.140	Up-regulation
AGC_SGK_SGK1_ST	Q92542	NCSTN	O00141	SGK1	S425	Q420R	420	Missense	distal	-5	no	2.414	10.565	EPSD	GDSC;CCLE	9.140	Gain
AGC_SGK_SGK1_ST	P46527	CDKN1B	O00141	SGK1	T157	P155L	155	Missense	proximal	-2	no	16.770	17.145	PhosphoSitePlus;EPSD	GDSC;CCLE	9.140	Up-regulation
AGC_SGK_SGK1_ST	Q9Y2V2	CARHSP1	O00141	SGK1	T50	A53E	53	Missense	distal	3	no	12.625	12.372	EPSD	GDSC	9.140	Down-regulation
AGC_SGK_SGK1_ST	Q9Y2V2	CARHSP1	O00141	SGK1	S52	A53E	53	Missense	proximal	1	no	16.115	16.190	PhosphoSitePlus	GDSC	9.140	Up-regulation
AGC_SGK_SGK1_ST	Q9Y2V2	CARHSP1	O00141	SGK1	T54	A53E	53	Missense	proximal	-1	no	9.750	9.650	EPSD	GDSC	9.140	Down-regulation
AGC_SGK_SGK1_ST	Q9H4A3	WNK1	O00141	SGK1	S167	L171F	171	Missense	distal	4	no	13.383	13.082	EPSD	GDSC;CCLE	9.140	Down-regulation
AGC_SGK_SGK1_ST	P14672	SLC2A4	O00141	SGK1	S274	R269H	269	Missense	distal	-5	no	17.937	10.604	PhosphoSitePlus	GDSC;CCLE	9.140	Down-regulation
AGC_SGK_SGK1_ST	P14672	SLC2A4	O00141	SGK1	S274	G280C	280	Missense	distal	6	no	17.937	18.109	PhosphoSitePlus	GDSC;CCLE	9.140	Up-regulation
AGC_SGK_SGK1_ST	O43524	FOXO3	O00141	SGK1	S253	R249W	249	Missense	distal	-4	no	17.222	16.004	EPSD	GDSC;CCLE	9.140	Down-regulation
AGC_SGK_SGK1_ST	O43524	FOXO3	O00141	SGK1	S315	V320I	320	Missense	distal	5	no	19.864	19.877	PhosphoSitePlus	GDSC;CCLE	9.140	Up-regulation
AGC_SGK_SGK1_ST	O43524	FOXO3	O00141	SGK1	S318	V320I	320	Missense	proximal	2	no	10.089	10.116	EPSD	GDSC;CCLE	9.140	Up-regulation
AGC_SGK_SGK1_ST	O43524	FOXO3	O00141	SGK1	S413	R410W	410	Missense	distal	-3	no	10.023	0.328	EPSD	GDSC;CCLE	9.140	Loss
AGC_SGK_SGK1_ST	O43524	FOXO3	O00141	SGK1	S413	M408V	408	Missense	distal	-5	no	10.023	8.292	EPSD	GDSC;CCLE	9.140	Loss
AGC_SGK_SGK1_ST	P28482	MAPK1	O00141	SGK1	T190	T185A	185	Missense	distal	-5	no	9.577	9.693	EPSD	GDSC;CCLE	9.140	Up-regulation
AGC_SGK_SGK1_ST	Q96J92	WNK4	O00141	SGK1	S47	R41G	41	Missense	distal	-6	no	18.127	17.962	EPSD	GDSC;CCLE	9.140	Down-regulation
AGC_SGK_SGK1_ST	Q96J92	WNK4	O00141	SGK1	S331	S331F	331	Missense	central	0	yes	9.204	0.000	EPSD	GDSC;CCLE	9.140	Loss
AGC_SGK_SGK1_ST	Q96J92	WNK4	O00141	SGK1	S680	R675W	675	Missense	distal	-5	no	17.705	10.047	EPSD	GDSC;CCLE	9.140	Down-regulation
AGC_SGK_SGK1_ST	Q96J92	WNK4	O00141	SGK1	S682	R675W	675	Missense	distal	-7	no	10.977	12.091	EPSD	GDSC;CCLE	9.140	Up-regulation
AGC_SGK_SGK1_ST	Q96J92	WNK4	O00141	SGK1	T1034	E1027D	1027	Missense	distal	-7	no	11.674	11.534	EPSD	GDSC;CCLE	9.140	Down-regulation
AGC_SGK_SGK1_ST	Q9Y2I7	PIKFYVE	O00141	SGK1	T22	P21A	21	Missense	proximal	-1	no	12.881	13.040	EPSD	GDSC;CCLE	9.140	Up-regulation
AGC_SGK_SGK1_ST	Q9Y2I7	PIKFYVE	O00141	SGK1	S25	P21A	21	Missense	distal	-4	no	10.456	11.352	EPSD	GDSC;CCLE	9.140	Up-regulation
AGC_SGK_SGK1_ST	Q9Y2I7	PIKFYVE	O00141	SGK1	T90	S88P	88	Missense	proximal	-2	no	12.209	11.722	EPSD	GDSC;CCLE	9.140	Down-regulation
AGC_SGK_SGK1_ST	Q9Y2I7	PIKFYVE	O00141	SGK1	S105	A106V	106	Missense	proximal	1	no	12.382	12.552	EPSD	GDSC;CCLE	9.140	Up-regulation
AGC_SGK_SGK1_ST	Q9Y2I7	PIKFYVE	O00141	SGK1	S223	I229V	229	Missense	distal	6	no	12.585	12.541	EPSD	GDSC	9.140	Down-regulation
AGC_SGK_SGK1_ST	Q9Y2I7	PIKFYVE	O00141	SGK1	S291	Q293P	293	Missense	proximal	2	no	10.858	10.959	EPSD	GDSC;CCLE	9.140	Up-regulation
AGC_SGK_SGK1_ST	Q9Y2I7	PIKFYVE	O00141	SGK1	S329	Q331H	331	Missense	proximal	2	no	11.434	11.423	EPSD	GDSC	9.140	Down-regulation
AGC_SGK_SGK1_ST	Q9Y2I7	PIKFYVE	O00141	SGK1	T341	V337F	337	Missense	distal	-4	no	10.930	10.404	EPSD	GDSC;CCLE	9.140	Down-regulation
AGC_SGK_SGK1_ST	Q9Y2I7	PIKFYVE	O00141	SGK1	S1549	R1546L	1546	Missense	distal	-3	no	12.337	6.988	EPSD	GDSC;CCLE	9.140	Loss
AGC_SGK_SGK1_ST	Q6R327	RICTOR	O00141	SGK1	S35	R32L	32	Missense	distal	-3	no	13.983	8.635	EPSD	GDSC;CCLE	9.140	Loss
AGC_SGK_SGK1_ST	Q6R327	RICTOR	O00141	SGK1	S1035	H1033Y	1033	Missense	proximal	-2	no	12.473	12.660	EPSD	GDSC	9.140	Up-regulation
AGC_SGK_SGK1_ST	Q6R327	RICTOR	O00141	SGK1	S1162	N1166K	1166	Missense	distal	4	no	10.736	10.899	EPSD	GDSC;CCLE	9.140	Up-regulation
AGC_SGK_SGK1_ST	Q6R327	RICTOR	O00141	SGK1	S1162	L1159V	1159	Missense	distal	-3	no	10.736	4.365	EPSD	GDSC;CCLE	9.140	Loss
AGC_SGK_SGK1_ST	Q6R327	RICTOR	O00141	SGK1	S1408	R1405*	1405	Missense	distal	-3	no	10.658	-0.084	EPSD	GDSC	9.140	Loss
AGC_SGK_SGK1_ST	P45985	MAP2K4	O00141	SGK1	S80	S80I	80	Missense	central	0	yes	20.300	0.000	PhosphoSitePlus	GDSC;CCLE	9.140	Loss
AGC_SGK_SGK1_ST	P45985	MAP2K4	O00141	SGK1	S292	W291*	291	Missense	proximal	-1	no	10.208	10.176	EPSD	GDSC	9.140	Down-regulation
AGC_SGK_SGK1_ST	O14920	IKBKB	O00141	SGK1	T23	R20H	20	Missense	distal	-3	no	11.541	1.923	EPSD	GDSC;CCLE	9.140	Loss
AGC_SGK_SGK1_ST	O14920	IKBKB	O00141	SGK1	S239	D242N	242	Missense	distal	3	no	9.764	9.854	EPSD	GDSC;CCLE	9.140	Up-regulation
AGC_SGK_SGK1_ST	P42858	HTT	O00141	SGK1	S417	R416C	416	Missense	proximal	-1	no	10.943	10.822	EPSD	GDSC;CCLE	9.140	Down-regulation
AGC_SGK_SGK1_ST	P42858	HTT	O00141	SGK1	S417	R414*	414	Missense	distal	-3	no	10.943	0.201	EPSD	GDSC	9.140	Loss
AGC_SGK_SGK1_ST	P42858	HTT	O00141	SGK1	S419	R416C	416	Missense	distal	-3	no	21.602	13.540	PhosphoSitePlus	GDSC;CCLE	9.140	Down-regulation
AGC_SGK_SGK1_ST	P42858	HTT	O00141	SGK1	S419	R414*	414	Missense	distal	-5	no	21.602	13.254	PhosphoSitePlus	GDSC	9.140	Down-regulation
AGC_SGK_SGK1_ST	P42858	HTT	O00141	SGK1	S1171	L1178V	1178	Missense	distal	7	no	10.038	10.193	EPSD	GDSC;CCLE	9.140	Up-regulation
AGC_SGK_SGK1_ST	P42858	HTT	O00141	SGK1	S1216	R1211G	1211	Missense	distal	-5	no	9.201	3.840	EPSD	GDSC;CCLE	9.140	Loss
AGC_SGK_SGK1_ST	P42858	HTT	O00141	SGK1	S2340	K2337R	2337	Missense	distal	-3	no	6.623	12.710	EPSD	GDSC	9.140	Gain
AGC_SGK_SGK1_ST	P42858	HTT	O00141	SGK1	S2812	L2814P	2814	Missense	proximal	2	no	9.523	9.416	EPSD	GDSC;CCLE	9.140	Down-regulation
AGC_SGK_SGK1_ST	Q969H0	FBXW7	O00141	SGK1	S18	R13*	13	Missense	distal	-5	no	11.099	2.751	EPSD	GDSC	9.140	Loss
AGC_SGK_SGK1_ST	Q969H0	FBXW7	O00141	SGK1	S18	K11Q	11	Missense	distal	-7	no	11.099	11.958	EPSD	GDSC;CCLE	9.140	Up-regulation
AGC_SGK_SGK1_ST	Q969H0	FBXW7	O00141	SGK1	T692	E694*	694	Missense	proximal	2	no	13.642	14.072	EPSD	GDSC	9.140	Up-regulation
TK_Jak_JAK1_Y	Q9NZJ5	EIF2AK3	P23458	JAK1	Y565	V568A	568	Missense	distal	3	no	9.587	9.783	EPSD	GDSC;CCLE	8.575	Up-regulation
TK_Jak_JAK1_Y	Q9NZJ5	EIF2AK3	P23458	JAK1	Y565	Q558E	558	Missense	distal	-7	no	9.587	10.091	EPSD	GDSC	8.575	Up-regulation
TK_Jak_JAK1_Y	Q99683	MAP3K5	P23458	JAK1	Y961	S955L	955	Missense	distal	-6	no	9.213	10.629	EPSD	GDSC;CCLE	8.575	Up-regulation
Atypical_TAF1_TAF1_ST	P52655	GTF2A1	P21675	TAF1	S280	E282K	282	Missense	proximal	2	no	6.397	5.604	EPSD	GDSC;CCLE	2.466	Down-regulation
Atypical_TAF1_TAF1_ST	P52655	GTF2A1	P21675	TAF1	S281	E282K	282	Missense	proximal	1	no	6.891	5.662	EPSD	GDSC;CCLE	2.466	Down-regulation
Atypical_TAF1_TAF1_ST	P52655	GTF2A1	P21675	TAF1	S316	E323K	323	Missense	distal	7	no	7.437	7.411	EPSD;PhosphoSitePlus	GDSC;CCLE	2.466	Down-regulation
Atypical_TAF1_TAF1_ST	P52655	GTF2A1	P21675	TAF1	S321	E323K	323	Missense	proximal	2	no	7.637	6.844	PhosphoSitePlus;EPSD	GDSC;CCLE	2.466	Down-regulation
Atypical_TAF1_TAF1_ST	Q15545	TAF7	P21675	TAF1	S228	E221K	221	Missense	distal	-7	no	1.952	2.706	EPSD	GDSC;CCLE	2.466	Gain
Atypical_TAF1_TAF1_ST	P04637	TP53	P21675	TAF1	T55	E56*	56	Missense	proximal	1	no	6.462	5.214	PhosphoSitePlus	GDSC	2.466	Down-regulation
Atypical_TAF1_TAF1_ST	P04637	TP53	P21675	TAF1	T55	E62*	62	Missense	distal	7	no	6.462	6.387	PhosphoSitePlus	GDSC	2.466	Down-regulation
Atypical_TAF1_TAF1_ST	P04637	TP53	P21675	TAF1	S183	S183*	183	Missense	central	0	yes	3.336	0.000	EPSD	GDSC	2.466	Loss
Atypical_TAF1_TAF1_ST	P04637	TP53	P21675	TAF1	S183	E180*	180	Missense	distal	-3	no	3.336	3.668	EPSD	GDSC	2.466	Up-regulation
Atypical_TAF1_TAF1_ST	P04637	TP53	P21675	TAF1	S313	R306*	306	Missense	distal	-7	no	3.173	3.165	EPSD	GDSC	2.466	Down-regulation
Atypical_TAF1_TAF1_ST	P04637	TP53	P21675	TAF1	S313	Q317*	317	Missense	distal	4	no	3.173	3.140	EPSD	GDSC	2.466	Down-regulation
Atypical_TAF1_TAF1_ST	P04637	TP53	P21675	TAF1	S313	K319*	319	Missense	distal	6	no	3.173	3.195	EPSD	GDSC	2.466	Up-regulation
Atypical_TAF1_TAF1_ST	P04637	TP53	P21675	TAF1	T387	G389W	389	Missense	proximal	2	no	2.456	2.963	EPSD	GDSC;CCLE	2.466	Gain
Atypical_TAF1_TAF1_ST	P04637	TP53	P21675	TAF1	S392	G389W	389	Missense	distal	-3	no	2.497	2.338	EPSD	GDSC;CCLE	2.466	Loss
TK_Abl_ABL1_Y	P37840	SNCA	P00519	ABL1	Y125	M127I	127	Missense	proximal	2	no	11.633	12.067	EPSD;PhosphoSitePlus	GDSC	7.039	Up-regulation
TK_Abl_ABL1_Y	P37840	SNCA	P00519	ABL1	Y125	E130G	130	Missense	distal	5	no	11.633	12.341	EPSD;PhosphoSitePlus	GDSC	7.039	Up-regulation
TK_Abl_ABL1_Y	P37840	SNCA	P00519	ABL1	Y136	E130G	130	Missense	distal	-6	no	8.117	7.907	EPSD	GDSC	7.039	Down-regulation
TK_Abl_ABL1_Y	Q9UL17	TBX21	P00519	ABL1	Y118	Y118C	118	Missense	central	0	yes	7.053	0.000	EPSD	GDSC;CCLE	7.039	Loss
TK_Abl_ABL1_Y	Q9UL17	TBX21	P00519	ABL1	Y118	P119L	119	Missense	proximal	1	no	7.053	6.310	EPSD	GDSC;CCLE	7.039	Loss
TK_Abl_ABL1_Y	Q9UL17	TBX21	P00519	ABL1	Y125	Y118C	118	Missense	distal	-7	no	10.001	9.939	EPSD	GDSC;CCLE	7.039	Down-regulation
TK_Abl_ABL1_Y	Q9UL17	TBX21	P00519	ABL1	Y125	P119L	119	Missense	distal	-6	no	10.001	9.848	EPSD	GDSC;CCLE	7.039	Down-regulation
TK_Abl_ABL1_Y	P04040	CAT	P00519	ABL1	Y386	Y379F	379	Missense	distal	-7	no	7.047	6.841	EPSD;PhosphoSitePlus	GDSC;CCLE	7.039	Loss
TK_Abl_ABL1_Y	Q15746	MYLK	P00519	ABL1	Y1635	G1639R	1639	Missense	distal	4	no	7.901	8.187	EPSD;PhosphoSitePlus	GDSC;CCLE	7.039	Up-regulation
TK_Abl_ABL1_Y	O15350	TP73	P00519	ABL1	Y99	P98S	98	Missense	proximal	-1	no	11.076	9.486	PhosphoSitePlus	GDSC;CCLE	7.039	Down-regulation
TK_Abl_ABL1_Y	Q03135	CAV1	P00519	ABL1	Y25	N23S	23	Missense	proximal	-2	no	7.852	7.966	EPSD	GDSC	7.039	Up-regulation
TK_Abl_ABL1_Y	Q06609	RAD51	P00519	ABL1	Y54	E50D	50	Missense	distal	-4	no	7.756	6.470	EPSD;PhosphoSitePlus	GDSC;CCLE	7.039	Loss
TK_Abl_ABL1_Y	Q06609	RAD51	P00519	ABL1	Y54	K57R	57	Missense	distal	3	no	7.756	6.284	EPSD;PhosphoSitePlus	GDSC	7.039	Loss
TK_Abl_ABL1_Y	P03372	ESR1	P00519	ABL1	Y328	D321N	321	Missense	distal	-7	no	7.495	8.048	EPSD	GDSC;CCLE	7.039	Up-regulation
TK_Abl_ABL1_Y	Q13535	ATR	P00519	ABL1	Y1479	L1483F	1483	Missense	distal	4	no	7.363	7.179	EPSD	GDSC;CCLE	7.039	Down-regulation
TK_Abl_ABL1_Y	Q13535	ATR	P00519	ABL1	Y1956	R1959M	1959	Missense	distal	3	no	6.621	8.333	EPSD	GDSC;CCLE	7.039	Gain
TK_Abl_ABL1_Y	P11274	BCR	P00519	ABL1	Y177	F176L	176	Missense	proximal	-1	no	6.727	7.515	PhosphoSitePlus	GDSC;CCLE	7.039	Gain
TK_Abl_ABL1_Y	P11274	BCR	P00519	ABL1	Y283	Y279H	279	Missense	distal	-4	no	8.285	7.252	EPSD	GDSC;CCLE	7.039	Down-regulation
TK_Abl_ABL1_Y	P11274	BCR	P00519	ABL1	Y360	R361C	361	Missense	proximal	1	no	9.495	8.723	EPSD	GDSC;CCLE	7.039	Down-regulation
TK_Abl_ABL1_Y	P11274	BCR	P00519	ABL1	Y455	I456T	456	Missense	proximal	1	no	8.418	8.954	EPSD	GDSC	7.039	Up-regulation
TK_Abl_ABL1_Y	P11274	BCR	P00519	ABL1	Y554	V550M	550	Missense	distal	-4	no	7.654	6.905	EPSD	GDSC;CCLE	7.039	Loss
TK_Abl_ABL1_Y	P19174	PLCG1	P00519	ABL1	Y162	V164M	164	Missense	proximal	2	no	7.137	7.679	EPSD	GDSC;CCLE	7.039	Up-regulation
TK_Abl_ABL1_Y	P19174	PLCG1	P00519	ABL1	Y783	E785K	785	Missense	proximal	2	no	8.857	8.875	EPSD	GDSC;CCLE	7.039	Up-regulation
TK_Abl_ABL1_Y	P08581	MET	P00519	ABL1	Y745	D741N	741	Missense	distal	-4	no	8.513	8.891	EPSD	GDSC;CCLE	7.039	Up-regulation
TK_Abl_ABL1_Y	P08581	MET	P00519	ABL1	Y1159	R1166*	1166	Missense	distal	7	no	7.456	7.428	EPSD	GDSC	7.039	Down-regulation
TK_Abl_ABL1_Y	Q06187	BTK	P00519	ABL1	Y551	D549A	549	Missense	proximal	-2	no	8.504	8.563	EPSD	GDSC;CCLE	7.039	Up-regulation
TK_Abl_ABL1_Y	P53350	PLK1	P00519	ABL1	Y217	S224R	224	Missense	distal	7	no	9.779	9.793	PhosphoSitePlus;EPSD	GDSC;CCLE	7.039	Up-regulation
TK_Abl_ABL1_Y	Q13573	SNW1	P00519	ABL1	Y292	R299P	299	Missense	distal	7	no	7.093	7.087	PhosphoSitePlus;EPSD	GDSC	7.039	Down-regulation
TK_Abl_ABL1_Y	Q6ZUJ8	PIK3AP1	P00519	ABL1	Y570	R577T	577	Missense	distal	7	no	10.002	10.021	PhosphoSitePlus;EPSD	GDSC	7.039	Up-regulation
TK_Abl_ABL1_Y	P09619	PDGFRB	P00519	ABL1	Y686	I679N	679	Missense	distal	-7	no	7.265	8.254	EPSD;PhosphoSitePlus	GDSC	7.039	Up-regulation
TK_Abl_ABL1_Y	P09619	PDGFRB	P00519	ABL1	Y751	M754T	754	Missense	distal	3	no	7.940	7.323	EPSD	GDSC;CCLE	7.039	Down-regulation
TK_Abl_ABL1_Y	P09619	PDGFRB	P00519	ABL1	Y771	P774L	774	Missense	distal	3	no	8.867	6.289	EPSD	GDSC;CCLE	7.039	Loss
TK_Abl_ABL1_Y	P09619	PDGFRB	P00519	ABL1	Y934	M937V	937	Missense	distal	3	no	8.950	9.958	EPSD;PhosphoSitePlus	GDSC;CCLE	7.039	Up-regulation
TK_Abl_ABL1_Y	Q14247	CTTN	P00519	ABL1	Y104	K97N	97	Missense	distal	-7	no	6.946	7.531	EPSD	GDSC	7.039	Gain
TK_Abl_ABL1_Y	Q14247	CTTN	P00519	ABL1	Y486	E490K	490	Missense	distal	4	no	9.676	9.302	PhosphoSitePlus	GDSC;CCLE	7.039	Down-regulation
TK_Abl_ABL1_Y	Q9H3D4	TP63	P00519	ABL1	Y149	T155I	155	Missense	distal	6	no	11.962	11.939	EPSD;PhosphoSitePlus	GDSC;CCLE	7.039	Down-regulation
TK_Abl_ABL1_Y	Q14498	RBM39	P00519	ABL1	Y95	G101*	101	Missense	distal	6	no	8.709	8.628	PhosphoSitePlus;EPSD	GDSC	7.039	Down-regulation
TK_Abl_ABL1_Y	Q14498	RBM39	P00519	ABL1	Y99	G101*	101	Missense	proximal	2	no	11.761	10.603	EPSD;PhosphoSitePlus	GDSC	7.039	Down-regulation
TK_Abl_ABL1_Y	Q14498	RBM39	P00519	ABL1	Y99	S106N	106	Missense	distal	7	no	11.761	11.776	EPSD;PhosphoSitePlus	GDSC	7.039	Up-regulation
TK_Abl_ABL1_Y	P55211	CASP9	P00519	ABL1	Y397	Q399H	399	Missense	proximal	2	no	9.559	9.271	EPSD;PhosphoSitePlus	GDSC;CCLE	7.039	Down-regulation
TK_Abl_ABL1_Y	P55211	CASP9	P00519	ABL1	Y397	G402A	402	Missense	distal	5	no	9.559	9.137	EPSD;PhosphoSitePlus	GDSC;CCLE	7.039	Down-regulation
TK_Abl_ABL1_Y	P50402	EMD	P00519	ABL1	Y105	F100S	100	Missense	distal	-5	no	7.479	8.997	EPSD	GDSC;CCLE	7.039	Up-regulation
TK_Abl_ABL1_Y	O15162	PLSCR1	P00519	ABL1	Y69	N65K	65	Missense	distal	-4	no	10.711	8.954	PhosphoSitePlus;EPSD	GDSC	7.039	Down-regulation
TK_Abl_ABL1_Y	P04083	ANXA1	P00519	ABL1	Y207	D200H	200	Missense	distal	-7	no	7.140	6.794	EPSD	GDSC;CCLE	7.039	Loss
TK_Abl_ABL1_Y	P04083	ANXA1	P00519	ABL1	Y207	S201*	201	Missense	distal	-6	no	7.140	6.895	EPSD	GDSC	7.039	Loss
TK_Abl_ABL1_Y	P49023	PXN	P00519	ABL1	Y88	V87E	87	Missense	proximal	-1	no	6.760	7.462	EPSD	GDSC	7.039	Gain
TK_Abl_ABL1_Y	P49023	PXN	P00519	ABL1	Y181	S188R	188	Missense	distal	7	no	7.226	7.240	EPSD	GDSC	7.039	Up-regulation
TK_Abl_ABL1_Y	P46109	CRKL	P00519	ABL1	Y61	E54D	54	Missense	distal	-7	no	8.719	8.992	EPSD	GDSC;CCLE	7.039	Up-regulation
TK_Abl_ABL1_Y	P46109	CRKL	P00519	ABL1	Y132	R129W	129	Missense	distal	-3	no	8.338	7.666	EPSD	GDSC	7.039	Down-regulation
TK_Abl_ABL1_Y	P15498	VAV1	P00519	ABL1	Y727	I720S	720	Missense	distal	-7	no	6.869	7.190	EPSD	GDSC;CCLE	7.039	Gain
TK_Abl_ABL1_Y	P15498	VAV1	P00519	ABL1	Y841	E843K	843	Missense	proximal	2	no	8.589	8.606	EPSD	GDSC;CCLE	7.039	Up-regulation
TK_Abl_ABL1_Y	P15498	VAV1	P00519	ABL1	Y844	E843K	843	Missense	proximal	-1	no	7.917	6.223	EPSD	GDSC;CCLE	7.039	Loss
TK_Abl_ABL1_Y	Q9UPY6	WASF3	P00519	ABL1	Y248	P251L	251	Missense	distal	3	no	11.586	9.009	EPSD;PhosphoSitePlus	GDSC	7.039	Down-regulation
TK_Abl_ABL1_Y	Q9UPY6	WASF3	P00519	ABL1	Y337	Y337C	337	Missense	central	0	yes	10.219	0.000	PhosphoSitePlus;EPSD	GDSC;CCLE	7.039	Loss
TK_Abl_ABL1_Y	Q9UPY6	WASF3	P00519	ABL1	Y486	D490G	490	Missense	distal	4	no	10.888	10.631	EPSD;PhosphoSitePlus	GDSC;CCLE	7.039	Down-regulation
TK_Abl_ABL1_Y	P17844	DDX5	P00519	ABL1	Y97	V93A	93	Missense	distal	-4	no	10.141	9.918	EPSD	GDSC;CCLE	7.039	Down-regulation
TK_Abl_ABL1_Y	P17844	DDX5	P00519	ABL1	Y535	A537T	537	Missense	proximal	2	no	10.897	10.704	EPSD	GDSC	7.039	Down-regulation
TK_Abl_ABL1_Y	Q9UPN9	TRIM33	P00519	ABL1	Y1018	K1012E	1012	Missense	distal	-6	no	11.528	11.738	EPSD	GDSC;CCLE	7.039	Up-regulation
TK_Abl_ABL1_Y	P46527	CDKN1B	P00519	ABL1	Y88	E86K	86	Missense	proximal	-2	no	9.490	8.818	EPSD;PhosphoSitePlus	GDSC;CCLE	7.039	Down-regulation
TK_Abl_ABL1_Y	P46527	CDKN1B	P00519	ABL1	Y89	E86K	86	Missense	distal	-3	no	10.249	9.222	PhosphoSitePlus;EPSD	GDSC;CCLE	7.039	Down-regulation
TK_Abl_ABL1_Y	Q14980	NUMA1	P00519	ABL1	Y1836	R1839W	1839	Missense	distal	3	no	4.879	7.205	EPSD	GDSC;CCLE	7.039	Gain
TK_Abl_ABL1_Y	P06400	RB1	P00519	ABL1	Y606	T601S	601	Missense	distal	-5	no	9.160	8.838	EPSD	GDSC;CCLE	7.039	Down-regulation
TK_Abl_ABL1_Y	P06400	RB1	P00519	ABL1	Y805	G801*	801	Missense	distal	-4	no	10.355	8.554	PhosphoSitePlus	GDSC	7.039	Down-regulation
TK_Abl_ABL1_Y	Q16531	DDB1	P00519	ABL1	Y517	Y517C	517	Missense	central	0	yes	7.406	0.000	EPSD	GDSC	7.039	Loss
TK_Abl_ABL1_Y	Q16531	DDB1	P00519	ABL1	Y517	V510A	510	Missense	distal	-7	no	7.406	7.138	EPSD	GDSC;CCLE	7.039	Down-regulation
TK_Abl_ABL1_Y	P17931	LGALS3	P00519	ABL1	Y79	G85D	85	Missense	distal	6	no	9.439	9.371	EPSD;PhosphoSitePlus	GDSC;CCLE	7.039	Down-regulation
TK_Abl_ABL1_Y	P17931	LGALS3	P00519	ABL1	Y79	G72R	72	Missense	distal	-7	no	9.439	9.549	EPSD;PhosphoSitePlus	GDSC;CCLE	7.039	Up-regulation
TK_Abl_ABL1_Y	P43403	ZAP70	P00519	ABL1	Y221	G226D	226	Missense	distal	5	no	10.683	10.333	EPSD	GDSC;CCLE	7.039	Down-regulation
TK_Abl_ABL1_Y	Q8IZP0	ABI1	P00519	ABL1	Y474	M468I	468	Missense	distal	-6	no	7.780	7.871	EPSD	GDSC;CCLE	7.039	Up-regulation
TK_Abl_ABL1_Y	P15391	CD19	P00519	ABL1	Y508	Q512H	512	Missense	distal	4	no	9.625	9.381	PhosphoSitePlus	GDSC;CCLE	7.039	Down-regulation
TK_Abl_ABL1_Y	Q15139	PRKD1	P00519	ABL1	Y463	S460R	460	Missense	distal	-3	no	11.364	11.314	PhosphoSitePlus	GDSC	7.039	Down-regulation
TK_Abl_ABL1_Y	Q15139	PRKD1	P00519	ABL1	Y463	P467T	467	Missense	distal	4	no	11.364	11.286	PhosphoSitePlus	GDSC	7.039	Down-regulation
TK_Abl_ABL1_Y	O95433	AHSA1	P00519	ABL1	Y151	T154S	154	Missense	distal	3	no	7.313	7.724	EPSD	GDSC;CCLE	7.039	Up-regulation
TK_Abl_ABL1_Y	P11387	TOP1	P00519	ABL1	Y426	M428T	428	Missense	proximal	2	no	7.303	7.571	EPSD	GDSC;CCLE	7.039	Up-regulation
TK_Abl_ABL1_Y	P11387	TOP1	P00519	ABL1	Y537	V543L	543	Missense	distal	6	no	7.140	6.300	EPSD	GDSC	7.039	Loss
TK_Abl_ABL1_Y	P11387	TOP1	P00519	ABL1	Y538	V543L	543	Missense	distal	5	no	6.782	7.325	EPSD	GDSC	7.039	Gain
TK_Abl_ABL1_Y	P56962	STX17	P00519	ABL1	Y157	S150F	150	Missense	distal	-7	no	15.579	15.099	PhosphoSitePlus	GDSC;CCLE	7.039	Down-regulation
Other_CDC7_CDC7_ST	P19338	NCL	O00311	CDC7	T121	G115D	115	Missense	distal	-6	no	72.728	68.158	PhosphoSitePlus;EPSD	GDSC;CCLE	65.097	Down-regulation
Other_CDC7_CDC7_ST	P19338	NCL	O00311	CDC7	S206	E207K	207	Missense	proximal	1	no	77.704	55.894	EPSD	GDSC;CCLE	65.097	Loss
Other_CDC7_CDC7_ST	P19338	NCL	O00311	CDC7	S206	E209A	209	Missense	distal	3	no	77.704	77.539	EPSD	GDSC	65.097	Down-regulation
Other_CDC7_CDC7_ST	P19338	NCL	O00311	CDC7	S591	G594S	594	Missense	distal	3	no	77.786	78.078	EPSD	GDSC;CCLE	65.097	Up-regulation
Other_CDC7_CDC7_ST	P49736	MCM2	O00311	CDC7	S26	T25A	25	Missense	proximal	-1	no	74.298	73.547	EPSD	GDSC;CCLE	65.097	Down-regulation
Other_CDC7_CDC7_ST	P49736	MCM2	O00311	CDC7	S26	D22Y	22	Missense	distal	-4	no	74.298	76.873	EPSD	GDSC;CCLE	65.097	Up-regulation
Other_CDC7_CDC7_ST	P49736	MCM2	O00311	CDC7	S27	T25A	25	Missense	proximal	-2	no	82.312	80.414	EPSD;PhosphoSitePlus	GDSC;CCLE	65.097	Down-regulation
Other_CDC7_CDC7_ST	P49736	MCM2	O00311	CDC7	S27	D22Y	22	Missense	distal	-5	no	82.312	71.832	EPSD;PhosphoSitePlus	GDSC;CCLE	65.097	Down-regulation
Other_CDC7_CDC7_ST	P49736	MCM2	O00311	CDC7	S31	T25A	25	Missense	distal	-6	no	76.100	74.390	EPSD;PhosphoSitePlus	GDSC;CCLE	65.097	Down-regulation
Other_CDC7_CDC7_ST	P49736	MCM2	O00311	CDC7	S40	S40F	40	Missense	central	0	yes	80.370	0.000	EPSD;PhosphoSitePlus	GDSC;CCLE	65.097	Loss
Other_CDC7_CDC7_ST	P49736	MCM2	O00311	CDC7	S40	R44G	44	Missense	distal	4	no	80.370	79.880	EPSD;PhosphoSitePlus	GDSC;CCLE	65.097	Down-regulation
Other_CDC7_CDC7_ST	P49736	MCM2	O00311	CDC7	S40	P42L	42	Missense	proximal	2	no	80.370	78.679	EPSD;PhosphoSitePlus	GDSC;CCLE	65.097	Down-regulation
Other_CDC7_CDC7_ST	P49736	MCM2	O00311	CDC7	S41	S40F	40	Missense	proximal	-1	no	87.051	83.245	EPSD;PhosphoSitePlus	GDSC;CCLE	65.097	Down-regulation
Other_CDC7_CDC7_ST	P49736	MCM2	O00311	CDC7	S41	R44G	44	Missense	distal	3	no	87.051	86.840	EPSD;PhosphoSitePlus	GDSC;CCLE	65.097	Down-regulation
Other_CDC7_CDC7_ST	P49736	MCM2	O00311	CDC7	S41	P42L	42	Missense	proximal	1	no	87.051	65.472	EPSD;PhosphoSitePlus	GDSC;CCLE	65.097	Down-regulation
Other_CDC7_CDC7_ST	P49736	MCM2	O00311	CDC7	S53	E52Q	52	Missense	proximal	-1	no	80.927	79.062	EPSD;PhosphoSitePlus	GDSC;CCLE	65.097	Down-regulation
Other_CDC7_CDC7_ST	P49736	MCM2	O00311	CDC7	T59	E52Q	52	Missense	distal	-7	no	65.895	66.564	EPSD	GDSC;CCLE	65.097	Up-regulation
Other_CDC7_CDC7_ST	P49736	MCM2	O00311	CDC7	T59	G61E	61	Missense	proximal	2	no	65.895	65.887	EPSD	GDSC;CCLE	65.097	Down-regulation
Other_CDC7_CDC7_ST	P49736	MCM2	O00311	CDC7	S108	R115L	115	Missense	distal	7	no	77.445	78.496	EPSD;PhosphoSitePlus	GDSC;CCLE	65.097	Up-regulation
Other_CDC7_CDC7_ST	P49736	MCM2	O00311	CDC7	S566	T570I	570	Missense	distal	4	no	66.076	64.374	EPSD	GDSC;CCLE	65.097	Loss
Other_CDC7_CDC7_ST	P49736	MCM2	O00311	CDC7	S566	Y559C	559	Missense	distal	-7	no	66.076	59.125	EPSD	GDSC	65.097	Loss
Other_CDC7_CDC7_ST	P49736	MCM2	O00311	CDC7	T598	A603V	603	Missense	distal	5	no	63.683	65.239	EPSD	GDSC;CCLE	65.097	Gain
Other_CDC7_CDC7_ST	P49736	MCM2	O00311	CDC7	S610	A603V	603	Missense	distal	-7	no	59.514	65.939	EPSD	GDSC;CCLE	65.097	Gain
Other_CDC7_CDC7_ST	P49736	MCM2	O00311	CDC7	S759	V764A	764	Missense	distal	5	no	70.139	68.582	EPSD	GDSC;CCLE	65.097	Down-regulation
Other_CDC7_CDC7_ST	O00311	CDC7	O00311	CDC7	S16	R21Q	21	Missense	distal	5	no	70.888	70.818	EPSD	GDSC;CCLE	65.097	Down-regulation
Other_CDC7_CDC7_ST	O00311	CDC7	O00311	CDC7	S296	S299L	299	Missense	distal	3	no	79.325	79.099	EPSD;PhosphoSitePlus	GDSC;CCLE	65.097	Down-regulation
Other_CDC7_CDC7_ST	O00311	CDC7	O00311	CDC7	S297	S299L	299	Missense	proximal	2	no	77.322	71.716	EPSD;PhosphoSitePlus	GDSC;CCLE	65.097	Down-regulation
Other_CDC7_CDC7_ST	Q9HAW4	CLSPN	O00311	CDC7	S67	V61F	61	Missense	distal	-6	no	86.013	84.265	EPSD;PhosphoSitePlus	GDSC	65.097	Down-regulation
Other_CDC7_CDC7_ST	Q9HAW4	CLSPN	O00311	CDC7	S110	M115T	115	Missense	distal	5	no	100.627	100.241	EPSD;PhosphoSitePlus	GDSC;CCLE	65.097	Down-regulation
Other_CDC7_CDC7_ST	Q9HAW4	CLSPN	O00311	CDC7	S205	L209F	209	Missense	distal	4	no	65.611	64.768	EPSD	GDSC;CCLE	65.097	Loss
Other_CDC7_CDC7_ST	Q9HAW4	CLSPN	O00311	CDC7	S341	E346*	346	Missense	distal	5	no	66.744	67.710	EPSD	GDSC	65.097	Up-regulation
Other_CDC7_CDC7_ST	Q9HAW4	CLSPN	O00311	CDC7	S704	G702S	702	Missense	proximal	-2	no	79.769	78.341	EPSD;PhosphoSitePlus	GDSC;CCLE	65.097	Down-regulation
Other_CDC7_CDC7_ST	Q9HAW4	CLSPN	O00311	CDC7	S808	G805R	805	Missense	distal	-3	no	69.471	69.392	EPSD	GDSC	65.097	Down-regulation
Other_CDC7_CDC7_ST	Q9HAW4	CLSPN	O00311	CDC7	S825	P832L	832	Missense	distal	7	no	67.509	67.444	EPSD	GDSC	65.097	Down-regulation
Other_CDC7_CDC7_ST	P11388	TOP2A	O00311	CDC7	S1213	G1216C	1216	Missense	distal	3	no	78.221	78.154	EPSD;PhosphoSitePlus	GDSC	65.097	Down-regulation
Other_CDC7_CDC7_ST	P11388	TOP2A	O00311	CDC7	S1354	S1361F	1361	Missense	distal	7	no	67.328	68.866	EPSD	GDSC	65.097	Up-regulation
Other_CDC7_CDC7_ST	P11388	TOP2A	O00311	CDC7	S1391	S1392*	1392	Missense	proximal	1	no	69.016	45.358	EPSD	GDSC	65.097	Loss
Other_CDC7_CDC7_ST	P11388	TOP2A	O00311	CDC7	S1423	S1428P	1428	Missense	distal	5	no	70.745	71.553	EPSD	GDSC;CCLE	65.097	Up-regulation
Other_CDC7_CDC7_ST	P11388	TOP2A	O00311	CDC7	S1426	S1428P	1428	Missense	proximal	2	no	65.166	61.252	EPSD	GDSC;CCLE	65.097	Loss
Other_CDC7_CDC7_ST	Q9UBU7	DBF4	O00311	CDC7	S118	T116S	116	Missense	proximal	-2	no	66.103	64.580	EPSD	GDSC;CCLE	65.097	Loss
Other_CDC7_CDC7_ST	Q9UBU7	DBF4	O00311	CDC7	T194	K191T	191	Missense	distal	-3	no	75.044	74.913	EPSD	GDSC	65.097	Down-regulation
Other_CDC7_CDC7_ST	Q9UBU7	DBF4	O00311	CDC7	T194	S192T	192	Missense	proximal	-2	no	75.044	76.567	EPSD	GDSC;CCLE	65.097	Up-regulation
Other_CDC7_CDC7_ST	Q9UBU7	DBF4	O00311	CDC7	S195	R202I	202	Missense	distal	7	no	71.299	70.232	EPSD	GDSC;CCLE	65.097	Down-regulation
Other_CDC7_CDC7_ST	Q9UBU7	DBF4	O00311	CDC7	S195	K191T	191	Missense	distal	-4	no	71.299	71.194	EPSD	GDSC	65.097	Down-regulation
Other_CDC7_CDC7_ST	Q9UBU7	DBF4	O00311	CDC7	S195	S192T	192	Missense	distal	-3	no	71.299	71.149	EPSD	GDSC;CCLE	65.097	Down-regulation
Other_CDC7_CDC7_ST	Q9UBU7	DBF4	O00311	CDC7	S259	Q266E	266	Missense	distal	7	no	82.872	82.583	EPSD	GDSC;CCLE	65.097	Down-regulation
Other_CDC7_CDC7_ST	Q9UBU7	DBF4	O00311	CDC7	T273	Q266E	266	Missense	distal	-7	no	80.590	79.922	EPSD;PhosphoSitePlus	GDSC;CCLE	65.097	Down-regulation
Other_CDC7_CDC7_ST	Q9UBU7	DBF4	O00311	CDC7	T273	I271F	271	Missense	proximal	-2	no	80.590	80.842	EPSD;PhosphoSitePlus	GDSC	65.097	Up-regulation
Other_CDC7_CDC7_ST	Q9UBU7	DBF4	O00311	CDC7	S354	Y353N	353	Missense	proximal	-1	no	62.517	65.395	EPSD	GDSC;CCLE	65.097	Gain
Other_CDC7_CDC7_ST	Q9UBU7	DBF4	O00311	CDC7	S357	L358P	358	Missense	proximal	1	no	64.475	86.054	EPSD	GDSC;CCLE	65.097	Gain
Other_CDC7_CDC7_ST	Q9UBU7	DBF4	O00311	CDC7	S359	Y353N	353	Missense	distal	-6	no	83.320	80.078	EPSD	GDSC;CCLE	65.097	Down-regulation
Other_CDC7_CDC7_ST	Q9UBU7	DBF4	O00311	CDC7	S359	L358P	358	Missense	proximal	-1	no	83.320	82.801	EPSD	GDSC;CCLE	65.097	Down-regulation
Other_CDC7_CDC7_ST	P06748	NPM1	O00311	CDC7	S137	A144T	144	Missense	distal	7	no	78.837	77.758	PhosphoSitePlus;EPSD	GDSC;CCLE	65.097	Down-regulation
Other_CDC7_CDC7_ST	P06748	NPM1	O00311	CDC7	S218	P220L	220	Missense	proximal	2	no	67.510	65.818	EPSD	GDSC;CCLE	65.097	Down-regulation
Other_CDC7_CDC7_ST	O75475	PSIP1	O00311	CDC7	S273	E278G	278	Missense	distal	5	no	66.154	66.734	EPSD	GDSC	65.097	Up-regulation
Other_CDC7_CDC7_ST	O75475	PSIP1	O00311	CDC7	S275	E278G	278	Missense	distal	3	no	70.158	69.784	EPSD	GDSC	65.097	Down-regulation
Other_CDC7_CDC7_ST	Q9NS91	RAD18	O00311	CDC7	S158	E152*	152	Missense	distal	-6	no	79.534	78.438	EPSD	GDSC	65.097	Down-regulation
Other_CDC7_CDC7_ST	Q9NS91	RAD18	O00311	CDC7	S434	I427T	427	Missense	distal	-7	no	75.630	76.224	PhosphoSitePlus	GDSC	65.097	Up-regulation
CMGC_GSK_GSK3B_ST	P11388	TOP2A	P49841	GSK3B	T950	L944S	944	Missense	distal	-6	no	6.650	6.651	EPSD	GDSC;CCLE	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	P11388	TOP2A	P49841	GSK3B	S1213	G1216C	1216	Missense	distal	3	no	7.648	7.389	EPSD	GDSC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	P11388	TOP2A	P49841	GSK3B	S1354	S1361F	1361	Missense	distal	7	no	9.605	9.683	EPSD	GDSC	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	P11388	TOP2A	P49841	GSK3B	S1361	S1361F	1361	Missense	central	0	yes	10.106	0.000	PhosphoSitePlus	GDSC	6.007	Loss
CMGC_GSK_GSK3B_ST	P11388	TOP2A	P49841	GSK3B	S1387	S1392*	1392	Missense	distal	5	no	6.530	4.480	EPSD	GDSC	6.007	Loss
CMGC_GSK_GSK3B_ST	P11388	TOP2A	P49841	GSK3B	S1393	S1392*	1392	Missense	proximal	-1	no	7.378	7.169	EPSD	GDSC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	P11388	TOP2A	P49841	GSK3B	S1423	S1428P	1428	Missense	distal	5	no	5.159	6.113	EPSD	GDSC;CCLE	6.007	Gain
CMGC_GSK_GSK3B_ST	P36956	SREBF1	P49841	GSK3B	S386	L387P	387	Missense	proximal	1	no	4.053	6.914	EPSD	GDSC	6.007	Gain
CMGC_GSK_GSK3B_ST	P10636	MAPT	P49841	GSK3B	S46	Q49H	49	Missense	distal	3	no	9.947	9.956	EPSD;PhosphoSitePlus	GDSC	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	P10636	MAPT	P49841	GSK3B	S46	A41V	41	Missense	distal	-5	no	9.947	10.249	EPSD;PhosphoSitePlus	GDSC;CCLE	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	P10636	MAPT	P49841	GSK3B	T50	Q49H	49	Missense	proximal	-1	no	9.345	9.401	EPSD;PhosphoSitePlus	GDSC	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	P10636	MAPT	P49841	GSK3B	T52	Q49H	49	Missense	distal	-3	no	5.925	6.007	EPSD	GDSC	6.007	Gain
CMGC_GSK_GSK3B_ST	P10636	MAPT	P49841	GSK3B	S171	D177V	177	Missense	distal	6	no	6.238	6.236	EPSD	GDSC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	P10636	MAPT	P49841	GSK3B	S228	R222H	222	Missense	distal	-6	no	11.620	11.643	EPSD	GDSC;CCLE	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	P10636	MAPT	P49841	GSK3B	T470	A475V	475	Missense	distal	5	no	6.449	6.023	EPSD	GDSC;CCLE	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	P10636	MAPT	P49841	GSK3B	S637	V635I	635	Missense	proximal	-2	no	7.884	7.906	EPSD	GDSC	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	P10636	MAPT	P49841	GSK3B	S739	S739C	739	Missense	central	0	yes	8.627	0.000	EPSD	GDSC	6.007	Loss
CMGC_GSK_GSK3B_ST	Q8N122	RPTOR	P49841	GSK3B	S696	L694F	694	Missense	proximal	-2	no	7.052	6.795	EPSD	GDSC;CCLE	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	Q8N122	RPTOR	P49841	GSK3B	S711	R716I	716	Missense	distal	5	no	6.809	5.826	EPSD	GDSC;CCLE	6.007	Loss
CMGC_GSK_GSK3B_ST	Q8N122	RPTOR	P49841	GSK3B	S711	R718H	718	Missense	distal	7	no	6.809	6.997	EPSD	GDSC;CCLE	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	Q8N122	RPTOR	P49841	GSK3B	T714	R716I	716	Missense	proximal	2	no	6.633	6.675	EPSD	GDSC;CCLE	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	Q8N122	RPTOR	P49841	GSK3B	T714	R718H	718	Missense	distal	4	no	6.633	5.915	EPSD	GDSC;CCLE	6.007	Loss
CMGC_GSK_GSK3B_ST	Q8N122	RPTOR	P49841	GSK3B	S738	S734N	734	Missense	distal	-4	no	6.617	5.319	EPSD	GDSC;CCLE	6.007	Loss
CMGC_GSK_GSK3B_ST	Q8N122	RPTOR	P49841	GSK3B	S794	S798P	798	Missense	distal	4	no	6.209	3.238	EPSD	GDSC	6.007	Loss
CMGC_GSK_GSK3B_ST	Q8N122	RPTOR	P49841	GSK3B	S798	S798P	798	Missense	central	0	yes	7.131	0.000	EPSD	GDSC	6.007	Loss
CMGC_GSK_GSK3B_ST	Q8N122	RPTOR	P49841	GSK3B	S877	S881P	881	Missense	distal	4	no	10.498	7.527	EPSD;PhosphoSitePlus	GDSC;CCLE	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	Q8N122	RPTOR	P49841	GSK3B	S881	S881P	881	Missense	central	0	yes	7.749	0.000	EPSD	GDSC;CCLE	6.007	Loss
CMGC_GSK_GSK3B_ST	Q8N122	RPTOR	P49841	GSK3B	S882	S881P	881	Missense	proximal	-1	no	6.772	6.828	EPSD	GDSC;CCLE	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	Q8N122	RPTOR	P49841	GSK3B	T883	S881P	881	Missense	proximal	-2	no	5.800	6.057	EPSD	GDSC;CCLE	6.007	Gain
CMGC_GSK_GSK3B_ST	Q8N122	RPTOR	P49841	GSK3B	T917	Y916H	916	Missense	proximal	-1	no	6.035	6.123	EPSD	GDSC;CCLE	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	Q13541	EIF4EBP1	P49841	GSK3B	S65	P66T	66	Missense	proximal	1	no	7.228	4.037	PhosphoSitePlus;EPSD	GDSC	6.007	Loss
CMGC_GSK_GSK3B_ST	Q13541	EIF4EBP1	P49841	GSK3B	S101	G108S	108	Missense	distal	7	no	6.885	6.865	EPSD	GDSC;CCLE	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	P50895	BCAM	P49841	GSK3B	S206	T208M	208	Missense	proximal	2	no	6.864	6.167	EPSD	GDSC;CCLE	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	P50895	BCAM	P49841	GSK3B	S296	D294H	294	Missense	proximal	-2	no	6.134	6.044	EPSD	GDSC;CCLE	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	P50895	BCAM	P49841	GSK3B	S296	R292Q	292	Missense	distal	-4	no	6.134	6.491	EPSD	GDSC	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	P50895	BCAM	P49841	GSK3B	S296	G293E	293	Missense	distal	-3	no	6.134	6.151	EPSD	GDSC;CCLE	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	Q9UPN3	MACF1	P49841	GSK3B	S280	E283*	283	Missense	distal	3	no	6.510	6.262	EPSD	GDSC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	Q9UPN3	MACF1	P49841	GSK3B	T334	T341N	341	Missense	distal	7	no	6.277	6.459	EPSD	GDSC;CCLE	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	Q9UPN3	MACF1	P49841	GSK3B	S559	T562N	562	Missense	distal	3	no	6.119	6.200	EPSD	GDSC;CCLE	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	Q9UPN3	MACF1	P49841	GSK3B	S862	D864H	864	Missense	proximal	2	no	8.019	7.602	EPSD	GDSC;CCLE	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	Q00653	NFKB2	P49841	GSK3B	S707	D714N	714	Missense	distal	7	no	10.090	10.158	EPSD;PhosphoSitePlus	GDSC	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	Q00653	NFKB2	P49841	GSK3B	S711	D714N	714	Missense	distal	3	no	7.797	7.750	PhosphoSitePlus;EPSD	GDSC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	Q00653	NFKB2	P49841	GSK3B	S713	D714N	714	Missense	proximal	1	no	7.328	4.912	EPSD	GDSC	6.007	Loss
CMGC_GSK_GSK3B_ST	Q00653	NFKB2	P49841	GSK3B	T732	R729W	729	Missense	distal	-3	no	6.277	6.207	EPSD	GDSC;CCLE	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	O15294	OGT	P49841	GSK3B	S369	L367S	367	Missense	proximal	-2	no	6.082	6.156	EPSD	GDSC;CCLE	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	Q14449	GRB14	P49841	GSK3B	S423	S427C	427	Missense	distal	4	no	7.814	1.681	EPSD;PhosphoSitePlus	GDSC;CCLE	6.007	Loss
CMGC_GSK_GSK3B_ST	P49768	PSEN1	P49841	GSK3B	T327	N331S	331	Missense	distal	4	no	4.088	7.699	EPSD	GDSC	6.007	Gain
CMGC_GSK_GSK3B_ST	Q6PGQ7	BORA	P49841	GSK3B	S41	F45V	45	Missense	distal	4	no	5.867	7.091	EPSD	GDSC;CCLE	6.007	Gain
CMGC_GSK_GSK3B_ST	Q6PGQ7	BORA	P49841	GSK3B	S43	T38I	38	Missense	distal	-5	no	5.954	6.138	EPSD	GDSC;CCLE	6.007	Gain
CMGC_GSK_GSK3B_ST	Q6PGQ7	BORA	P49841	GSK3B	S43	F45V	45	Missense	proximal	2	no	5.954	6.030	EPSD	GDSC;CCLE	6.007	Gain
CMGC_GSK_GSK3B_ST	Q6PGQ7	BORA	P49841	GSK3B	S112	T115A	115	Missense	distal	3	no	7.110	6.806	EPSD	GDSC;CCLE	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	Q6PGQ7	BORA	P49841	GSK3B	S183	L187I	187	Missense	distal	4	no	6.500	5.895	EPSD	GDSC	6.007	Loss
CMGC_GSK_GSK3B_ST	Q6PGQ7	BORA	P49841	GSK3B	S183	E178K	178	Missense	distal	-5	no	6.500	6.269	EPSD	GDSC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	Q6PGQ7	BORA	P49841	GSK3B	S252	A258V	258	Missense	distal	6	no	7.365	7.356	EPSD	GDSC;CCLE	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	Q6PGQ7	BORA	P49841	GSK3B	S268	G264*	264	Missense	distal	-4	no	6.184	5.262	EPSD	GDSC	6.007	Loss
CMGC_GSK_GSK3B_ST	Q6PGQ7	BORA	P49841	GSK3B	S270	G264*	264	Missense	distal	-6	no	9.887	9.807	EPSD	GDSC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	O95863	SNAI1	P49841	GSK3B	S104	S111L	111	Missense	distal	7	no	9.476	9.462	PhosphoSitePlus;EPSD	GDSC;CCLE	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	O95863	SNAI1	P49841	GSK3B	S107	S111L	111	Missense	distal	4	no	11.906	9.189	EPSD;PhosphoSitePlus	GDSC;CCLE	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	O95863	SNAI1	P49841	GSK3B	S111	S111L	111	Missense	central	0	yes	6.721	0.000	EPSD;PhosphoSitePlus	GDSC;CCLE	6.007	Loss
CMGC_GSK_GSK3B_ST	O95863	SNAI1	P49841	GSK3B	S115	S111L	111	Missense	distal	-4	no	6.986	5.635	EPSD;PhosphoSitePlus	GDSC;CCLE	6.007	Loss
CMGC_GSK_GSK3B_ST	P19793	RXRA	P49841	GSK3B	S17	P22L	22	Missense	distal	5	no	7.134	5.854	EPSD	GDSC	6.007	Loss
CMGC_GSK_GSK3B_ST	P19793	RXRA	P49841	GSK3B	S21	R25*	25	Missense	distal	4	no	6.940	9.366	EPSD	GDSC	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	P19793	RXRA	P49841	GSK3B	S21	P22L	22	Missense	proximal	1	no	6.940	4.079	EPSD	GDSC	6.007	Loss
CMGC_GSK_GSK3B_ST	P19793	RXRA	P49841	GSK3B	S66	S66L	66	Missense	central	0	yes	7.961	0.000	EPSD;PhosphoSitePlus	GDSC;CCLE	6.007	Loss
CMGC_GSK_GSK3B_ST	P05412	JUN	P49841	GSK3B	T91	H87R	87	Missense	distal	-4	no	8.831	8.732	EPSD	GDSC;CCLE	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	P05412	JUN	P49841	GSK3B	T93	H87R	87	Missense	distal	-6	no	6.874	6.851	EPSD	GDSC;CCLE	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	P05412	JUN	P49841	GSK3B	T231	L225M	225	Missense	distal	-6	no	7.587	7.535	EPSD	GDSC;CCLE	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	P05412	JUN	P49841	GSK3B	T231	E234D	234	Missense	distal	3	no	7.587	7.701	EPSD	GDSC;CCLE	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	P05412	JUN	P49841	GSK3B	T239	E234D	234	Missense	distal	-5	no	10.446	10.288	EPSD;PhosphoSitePlus	GDSC;CCLE	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	Q9UMX1	SUFU	P49841	GSK3B	S342	A340T	340	Missense	proximal	-2	no	7.675	8.037	PhosphoSitePlus	GDSC	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	Q9UMX1	SUFU	P49841	GSK3B	S349	S351G	351	Missense	proximal	2	no	6.655	6.397	EPSD	GDSC;CCLE	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	O00213	APBB1	P49841	GSK3B	S287	S287C	287	Missense	central	0	yes	6.458	0.000	EPSD	GDSC;CCLE	6.007	Loss
CMGC_GSK_GSK3B_ST	O00213	APBB1	P49841	GSK3B	S287	S292I	292	Missense	distal	5	no	6.458	5.792	EPSD	GDSC;CCLE	6.007	Loss
CMGC_GSK_GSK3B_ST	O00213	APBB1	P49841	GSK3B	S289	S287C	287	Missense	proximal	-2	no	7.898	7.586	EPSD	GDSC;CCLE	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	O00213	APBB1	P49841	GSK3B	S289	S292I	292	Missense	distal	3	no	7.898	7.477	EPSD	GDSC;CCLE	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	O00213	APBB1	P49841	GSK3B	S347	E354*	354	Missense	distal	7	no	6.995	7.351	EPSD	GDSC	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	P03372	ESR1	P49841	GSK3B	S294	I298V	298	Missense	distal	4	no	5.747	6.679	EPSD	GDSC	6.007	Gain
CMGC_GSK_GSK3B_ST	P03372	ESR1	P49841	GSK3B	S305	K299N	299	Missense	distal	-6	no	6.457	6.518	EPSD	GDSC;CCLE	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	P03372	ESR1	P49841	GSK3B	S305	I298V	298	Missense	distal	-7	no	6.457	6.451	EPSD	GDSC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	O95271	TNKS	P49841	GSK3B	S218	F222L	222	Missense	distal	4	no	6.668	7.564	EPSD	GDSC;CCLE	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	O95271	TNKS	P49841	GSK3B	S978	T982I	982	Missense	distal	4	no	9.811	7.358	EPSD;PhosphoSitePlus	GDSC;CCLE	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	O95271	TNKS	P49841	GSK3B	T982	T982I	982	Missense	central	0	yes	8.175	0.000	PhosphoSitePlus;EPSD	GDSC;CCLE	6.007	Loss
CMGC_GSK_GSK3B_ST	O95271	TNKS	P49841	GSK3B	S987	T982I	982	Missense	distal	-5	no	5.869	6.052	EPSD;PhosphoSitePlus	GDSC;CCLE	6.007	Gain
CMGC_GSK_GSK3B_ST	O75925	PIAS1	P49841	GSK3B	S90	S92F	92	Missense	proximal	2	no	7.982	7.638	EPSD	GDSC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	O75925	PIAS1	P49841	GSK3B	S105	S106P	106	Missense	proximal	1	no	4.774	8.619	EPSD	GDSC;CCLE	6.007	Gain
CMGC_GSK_GSK3B_ST	O75925	PIAS1	P49841	GSK3B	S106	S106P	106	Missense	central	0	yes	6.364	0.000	EPSD	GDSC;CCLE	6.007	Loss
CMGC_GSK_GSK3B_ST	O75925	PIAS1	P49841	GSK3B	S506	V505A	505	Missense	proximal	-1	no	7.611	7.408	EPSD	GDSC;CCLE	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	O75925	PIAS1	P49841	GSK3B	S510	V505A	505	Missense	distal	-5	no	6.945	6.643	EPSD	GDSC;CCLE	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	P0DMV8	HSPA1A	P49841	GSK3B	T38	V42M	42	Missense	distal	4	no	6.490	6.645	EPSD	GDSC	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	P0DMV8	HSPA1A	P49841	GSK3B	T38	T38A	38	Missense	central	0	yes	6.490	0.000	EPSD	GDSC	6.007	Loss
CMGC_GSK_GSK3B_ST	Q14596	NBR1	P49841	GSK3B	S123	T127N	127	Missense	distal	4	no	7.385	4.643	EPSD	GDSC	6.007	Loss
CMGC_GSK_GSK3B_ST	Q14596	NBR1	P49841	GSK3B	S273	S273*	273	Missense	central	0	yes	6.780	0.000	EPSD	GDSC	6.007	Loss
CMGC_GSK_GSK3B_ST	Q14596	NBR1	P49841	GSK3B	S273	R279C	279	Missense	distal	6	no	6.780	6.771	EPSD	GDSC;CCLE	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	Q14596	NBR1	P49841	GSK3B	S590	P597L	597	Missense	distal	7	no	6.747	6.796	EPSD	GDSC;CCLE	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	Q14596	NBR1	P49841	GSK3B	S833	V828I	828	Missense	distal	-5	no	9.121	9.014	EPSD	GDSC;CCLE	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	P12036	NEFH	P49841	GSK3B	S503	E508Q	508	Missense	distal	5	no	9.470	9.139	PhosphoSitePlus	GDSC;CCLE	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	P12036	NEFH	P49841	GSK3B	S511	E508Q	508	Missense	distal	-3	no	6.010	6.027	EPSD	GDSC;CCLE	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	P12036	NEFH	P49841	GSK3B	S620	K623E	623	Missense	distal	3	no	6.904	7.011	EPSD	GDSC;CCLE	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	P12036	NEFH	P49841	GSK3B	S620	A626G	626	Missense	distal	6	no	6.904	6.902	EPSD	GDSC;CCLE	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	P12036	NEFH	P49841	GSK3B	S640	K647N	647	Missense	distal	7	no	7.717	7.909	EPSD	GDSC	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	P12036	NEFH	P49841	GSK3B	S654	K647N	647	Missense	distal	-7	no	6.622	6.606	EPSD	GDSC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	P12036	NEFH	P49841	GSK3B	S660	E664V	664	Missense	distal	4	no	7.222	6.853	EPSD	GDSC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	P12036	NEFH	P49841	GSK3B	S660	A666T	666	Missense	distal	6	no	7.222	7.226	EPSD	GDSC;CCLE	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	P12036	NEFH	P49841	GSK3B	S668	E664V	664	Missense	distal	-4	no	6.532	5.896	EPSD	GDSC	6.007	Loss
CMGC_GSK_GSK3B_ST	P12036	NEFH	P49841	GSK3B	S668	A666T	666	Missense	proximal	-2	no	6.532	6.894	EPSD	GDSC;CCLE	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	P12036	NEFH	P49841	GSK3B	S688	A694D	694	Missense	distal	6	no	6.665	6.660	EPSD	GDSC;CCLE	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	P12036	NEFH	P49841	GSK3B	S696	A694D	694	Missense	proximal	-2	no	5.831	6.150	EPSD	GDSC;CCLE	6.007	Gain
CMGC_GSK_GSK3B_ST	P12036	NEFH	P49841	GSK3B	S730	K737N	737	Missense	distal	7	no	7.365	7.557	EPSD	GDSC;CCLE	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	P12036	NEFH	P49841	GSK3B	S744	K737N	737	Missense	distal	-7	no	7.026	7.011	EPSD	GDSC;CCLE	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	P12036	NEFH	P49841	GSK3B	S758	S752T	752	Missense	distal	-6	no	6.133	6.075	EPSD	GDSC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	P12036	NEFH	P49841	GSK3B	S793	P788T	788	Missense	distal	-5	no	5.954	6.399	EPSD	GDSC;CCLE	6.007	Gain
CMGC_GSK_GSK3B_ST	O00429	DNM1L	P49841	GSK3B	T189	T189R	189	Missense	central	0	yes	6.090	0.000	EPSD	GDSC	6.007	Loss
CMGC_GSK_GSK3B_ST	O00429	DNM1L	P49841	GSK3B	S544	A551T	551	Missense	distal	7	no	6.419	6.012	EPSD	GDSC;CCLE	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	O00429	DNM1L	P49841	GSK3B	S544	P547L	547	Missense	distal	3	no	6.419	6.101	EPSD	GDSC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	O00429	DNM1L	P49841	GSK3B	S544	A550D	550	Missense	distal	6	no	6.419	6.413	EPSD	GDSC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	O00429	DNM1L	P49841	GSK3B	S548	A551T	551	Missense	distal	3	no	10.349	10.654	EPSD	GDSC;CCLE	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	O00429	DNM1L	P49841	GSK3B	S548	P547L	547	Missense	proximal	-1	no	10.349	10.218	EPSD	GDSC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	O00429	DNM1L	P49841	GSK3B	S548	A550D	550	Missense	proximal	2	no	10.349	10.433	EPSD	GDSC	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	Q92908	GATA6	P49841	GSK3B	S33	F27L	27	Missense	distal	-6	no	6.374	6.426	EPSD	GDSC;CCLE	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	Q92908	GATA6	P49841	GSK3B	S37	S44F	44	Missense	distal	7	no	10.924	11.002	PhosphoSitePlus	GDSC;CCLE	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	Q92908	GATA6	P49841	GSK3B	S41	S44F	44	Missense	distal	3	no	6.029	5.819	EPSD	GDSC;CCLE	6.007	Loss
CMGC_GSK_GSK3B_ST	Q92908	GATA6	P49841	GSK3B	T62	E68V	68	Missense	distal	6	no	8.268	8.264	EPSD	GDSC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	Q92908	GATA6	P49841	GSK3B	S531	S531F	531	Missense	central	0	yes	8.241	0.000	EPSD	GDSC;CCLE	6.007	Loss
CMGC_GSK_GSK3B_ST	P17275	JUNB	P49841	GSK3B	T100	N96S	96	Missense	distal	-4	no	4.916	6.213	EPSD	GDSC;CCLE	6.007	Gain
CMGC_GSK_GSK3B_ST	P17275	JUNB	P49841	GSK3B	T102	N96S	96	Missense	distal	-6	no	7.614	7.616	EPSD	GDSC;CCLE	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	P30304	CDC25A	P49841	GSK3B	S283	S287N	287	Missense	distal	4	no	10.746	7.136	EPSD	GDSC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	P30304	CDC25A	P49841	GSK3B	S317	A319V	319	Missense	proximal	2	no	7.549	7.272	EPSD	GDSC;CCLE	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	P30304	CDC25A	P49841	GSK3B	S317	Q314*	314	Missense	distal	-3	no	7.549	7.708	EPSD	GDSC	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	P30304	CDC25A	P49841	GSK3B	S321	A319V	319	Missense	proximal	-2	no	7.617	7.919	EPSD	GDSC;CCLE	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	P30304	CDC25A	P49841	GSK3B	S321	Q314*	314	Missense	distal	-7	no	7.617	7.633	EPSD	GDSC	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	Q9NRR4	DROSHA	P49841	GSK3B	S255	R250Q	250	Missense	distal	-5	no	7.174	6.620	EPSD	GDSC;CCLE	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	Q9NRR4	DROSHA	P49841	GSK3B	S276	R283Q	283	Missense	distal	7	no	8.553	8.205	EPSD	GDSC;CCLE	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	Q9NRR4	DROSHA	P49841	GSK3B	S284	R291S	291	Missense	distal	7	no	6.751	6.314	EPSD	GDSC;CCLE	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	Q9NRR4	DROSHA	P49841	GSK3B	S284	R283Q	283	Missense	proximal	-1	no	6.751	6.782	EPSD	GDSC;CCLE	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	Q9NRR4	DROSHA	P49841	GSK3B	S300	D296G	296	Missense	distal	-4	no	9.866	10.038	EPSD;PhosphoSitePlus	GDSC;CCLE	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	Q9NRR4	DROSHA	P49841	GSK3B	S300	R305M	305	Missense	distal	5	no	9.866	9.411	EPSD;PhosphoSitePlus	GDSC;CCLE	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	Q9NRR4	DROSHA	P49841	GSK3B	T330	A327T	327	Missense	distal	-3	no	6.832	6.836	EPSD	GDSC;CCLE	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	Q9NRR4	DROSHA	P49841	GSK3B	T330	C329Y	329	Missense	proximal	-1	no	6.832	6.728	EPSD	GDSC;CCLE	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	Q9NRR4	DROSHA	P49841	GSK3B	S355	P356L	356	Missense	proximal	1	no	6.501	3.640	EPSD	GDSC;CCLE	6.007	Loss
CMGC_GSK_GSK3B_ST	Q9NRR4	DROSHA	P49841	GSK3B	S373	G379S	379	Missense	distal	6	no	6.783	6.787	EPSD	GDSC	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	Q9NRR4	DROSHA	P49841	GSK3B	T747	T743A	743	Missense	distal	-4	no	6.272	5.448	EPSD	GDSC;CCLE	6.007	Loss
CMGC_GSK_GSK3B_ST	P15924	DSP	P49841	GSK3B	T59	Q58*	58	Missense	proximal	-1	no	7.837	7.734	EPSD	GDSC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	P15924	DSP	P49841	GSK3B	S2607	S2608P	2608	Missense	proximal	1	no	3.077	6.922	EPSD	GDSC	6.007	Gain
CMGC_GSK_GSK3B_ST	P15924	DSP	P49841	GSK3B	T2612	E2614Q	2614	Missense	proximal	2	no	7.690	8.000	EPSD	GDSC;CCLE	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	P15924	DSP	P49841	GSK3B	T2612	S2608P	2608	Missense	distal	-4	no	7.690	7.127	EPSD	GDSC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	P15924	DSP	P49841	GSK3B	S2617	E2614Q	2614	Missense	distal	-3	no	6.490	6.507	EPSD	GDSC;CCLE	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	P15924	DSP	P49841	GSK3B	S2849	G2854R	2854	Missense	distal	5	no	6.665	6.939	EPSD;PhosphoSitePlus	GDSC;CCLE	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	P15924	DSP	P49841	GSK3B	T2853	G2854R	2854	Missense	proximal	1	no	6.657	7.531	EPSD	GDSC;CCLE	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	P15924	DSP	P49841	GSK3B	S2857	G2854R	2854	Missense	distal	-3	no	7.059	7.232	EPSD	GDSC;CCLE	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	P15924	DSP	P49841	GSK3B	S2861	G2854R	2854	Missense	distal	-7	no	8.185	8.205	EPSD	GDSC;CCLE	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	P60484	PTEN	P49841	GSK3B	S229	R233*	233	Missense	distal	4	no	5.015	7.442	EPSD	GDSC	6.007	Gain
CMGC_GSK_GSK3B_ST	P60484	PTEN	P49841	GSK3B	S294	Q298*	298	Missense	distal	4	no	4.107	7.059	EPSD	GDSC	6.007	Gain
CMGC_GSK_GSK3B_ST	P33076	CIITA	P49841	GSK3B	S288	P292S	292	Missense	distal	4	no	5.930	8.901	EPSD	GDSC;CCLE	6.007	Gain
CMGC_GSK_GSK3B_ST	P33076	CIITA	P49841	GSK3B	S288	P292A	292	Missense	distal	4	no	5.930	6.490	EPSD	GDSC;CCLE	6.007	Gain
CMGC_GSK_GSK3B_ST	Q14103	HNRNPD	P49841	GSK3B	S83	S87T	87	Missense	distal	4	no	11.052	10.184	PhosphoSitePlus	GDSC;CCLE	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	Q14103	HNRNPD	P49841	GSK3B	S83	H86P	86	Missense	distal	3	no	11.052	11.099	PhosphoSitePlus	GDSC;CCLE	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	Q14103	HNRNPD	P49841	GSK3B	S87	T91A	91	Missense	distal	4	no	6.223	4.680	EPSD	GDSC;CCLE	6.007	Loss
CMGC_GSK_GSK3B_ST	Q14103	HNRNPD	P49841	GSK3B	S87	H86P	86	Missense	proximal	-1	no	6.223	6.331	EPSD	GDSC;CCLE	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	Q14103	HNRNPD	P49841	GSK3B	T91	T91A	91	Missense	central	0	yes	6.257	0.000	EPSD	GDSC;CCLE	6.007	Loss
CMGC_GSK_GSK3B_ST	Q14103	HNRNPD	P49841	GSK3B	T91	S87T	87	Missense	distal	-4	no	6.257	5.922	EPSD	GDSC;CCLE	6.007	Loss
CMGC_GSK_GSK3B_ST	Q14103	HNRNPD	P49841	GSK3B	T91	H86P	86	Missense	distal	-5	no	6.257	5.934	EPSD	GDSC;CCLE	6.007	Loss
CMGC_GSK_GSK3B_ST	Q96KS0	EGLN2	P49841	GSK3B	S70	T72N	72	Missense	proximal	2	no	8.517	7.859	EPSD	GDSC;CCLE	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	Q96KS0	EGLN2	P49841	GSK3B	S74	T72N	72	Missense	proximal	-2	no	8.306	8.050	EPSD	GDSC;CCLE	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	Q96KS0	EGLN2	P49841	GSK3B	S130	E123K	123	Missense	distal	-7	no	8.108	8.097	EPSD	GDSC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	Q9UKA4	AKAP11	P49841	GSK3B	S29	Q32E	32	Missense	distal	3	no	7.135	7.153	EPSD	GDSC;CCLE	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	Q9UKA4	AKAP11	P49841	GSK3B	T269	S267*	267	Missense	proximal	-2	no	7.843	7.209	EPSD	GDSC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	Q9UKA4	AKAP11	P49841	GSK3B	T270	S267*	267	Missense	distal	-3	no	5.852	6.041	EPSD	GDSC	6.007	Gain
CMGC_GSK_GSK3B_ST	Q9UKA4	AKAP11	P49841	GSK3B	S273	S267*	267	Missense	distal	-6	no	6.050	5.987	EPSD	GDSC	6.007	Loss
CMGC_GSK_GSK3B_ST	Q9UKA4	AKAP11	P49841	GSK3B	S433	A430D	430	Missense	distal	-3	no	7.168	7.194	EPSD	GDSC;CCLE	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	Q9UKA4	AKAP11	P49841	GSK3B	S444	R451*	451	Missense	distal	7	no	10.311	10.269	EPSD	GDSC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	Q9UKA4	AKAP11	P49841	GSK3B	S448	R451*	451	Missense	distal	3	no	11.396	11.499	EPSD	GDSC	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	Q9UKA4	AKAP11	P49841	GSK3B	S452	R451*	451	Missense	proximal	-1	no	7.451	7.379	EPSD	GDSC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	Q9UKA4	AKAP11	P49841	GSK3B	S456	R451*	451	Missense	distal	-5	no	7.411	7.431	EPSD	GDSC	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	Q9UKA4	AKAP11	P49841	GSK3B	S483	D490H	490	Missense	distal	7	no	6.479	7.050	EPSD	GDSC;CCLE	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	Q9UKA4	AKAP11	P49841	GSK3B	S483	E479*	479	Missense	distal	-4	no	6.479	5.725	EPSD	GDSC	6.007	Loss
CMGC_GSK_GSK3B_ST	Q9UKA4	AKAP11	P49841	GSK3B	S978	P982S	982	Missense	distal	4	no	4.920	7.891	EPSD	GDSC;CCLE	6.007	Gain
CMGC_GSK_GSK3B_ST	Q9UKA4	AKAP11	P49841	GSK3B	T981	P982S	982	Missense	proximal	1	no	11.141	7.296	EPSD	GDSC;CCLE	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	Q9UKA4	AKAP11	P49841	GSK3B	S985	P982S	982	Missense	distal	-3	no	8.661	8.778	EPSD	GDSC;CCLE	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	Q9UKA4	AKAP11	P49841	GSK3B	S1242	S1249*	1249	Missense	distal	7	no	6.052	6.447	EPSD	GDSC	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	Q9NW38	FANCL	P49841	GSK3B	S77	L80V	80	Missense	distal	3	no	8.094	8.186	EPSD	GDSC	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	P56524	HDAC4	P49841	GSK3B	T394	S400L	400	Missense	distal	6	no	9.322	9.317	EPSD	GDSC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	P56524	HDAC4	P49841	GSK3B	S400	S400L	400	Missense	central	0	yes	7.430	0.000	EPSD	GDSC	6.007	Loss
CMGC_GSK_GSK3B_ST	O95997	PTTG1	P49841	GSK3B	T43	F50I	50	Missense	distal	7	no	5.825	6.083	EPSD	GDSC;CCLE	6.007	Gain
CMGC_GSK_GSK3B_ST	O95997	PTTG1	P49841	GSK3B	S165	G162C	162	Missense	distal	-3	no	7.639	7.746	EPSD	GDSC;CCLE	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	P14618	PKM	P49841	GSK3B	S406	A402V	402	Missense	distal	-4	no	6.023	5.949	EPSD	GDSC;CCLE	6.007	Loss
CMGC_GSK_GSK3B_ST	P49841	GSK3B	P49841	GSK3B	T7	T8P	8	Missense	proximal	1	no	4.452	7.643	EPSD	GDSC	6.007	Gain
CMGC_GSK_GSK3B_ST	P49841	GSK3B	P49841	GSK3B	S9	T8P	8	Missense	proximal	-1	no	6.632	6.763	EPSD	GDSC	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	P49841	GSK3B	P49841	GSK3B	S25	S21L	21	Missense	distal	-4	no	6.701	5.351	EPSD	GDSC;CCLE	6.007	Loss
CMGC_GSK_GSK3B_ST	Q96R06	SPAG5	P49841	GSK3B	S12	K19N	19	Missense	distal	7	no	6.787	6.980	EPSD	GDSC;CCLE	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	Q96R06	SPAG5	P49841	GSK3B	S14	K19N	19	Missense	distal	5	no	6.677	6.915	EPSD	GDSC;CCLE	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	Q96R06	SPAG5	P49841	GSK3B	S110	K113T	113	Missense	distal	3	no	6.052	6.146	EPSD	GDSC;CCLE	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	Q96R06	SPAG5	P49841	GSK3B	T111	K113T	113	Missense	proximal	2	no	10.369	10.542	EPSD;PhosphoSitePlus	GDSC;CCLE	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	Q96R06	SPAG5	P49841	GSK3B	S135	I130V	130	Missense	distal	-5	no	5.993	6.101	EPSD	GDSC;CCLE	6.007	Gain
CMGC_GSK_GSK3B_ST	Q96R06	SPAG5	P49841	GSK3B	S249	L246V	246	Missense	distal	-3	no	6.901	7.059	EPSD	GDSC;CCLE	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	Q96R06	SPAG5	P49841	GSK3B	T963	P960L	960	Missense	distal	-3	no	6.325	6.451	EPSD	GDSC;CCLE	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	O60341	KDM1A	P49841	GSK3B	S683	G679V	679	Missense	distal	-4	no	8.685	7.879	PhosphoSitePlus	GDSC;CCLE	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	Q9Y2X9	ZNF281	P49841	GSK3B	S160	E157G	157	Missense	distal	-3	no	7.051	7.033	EPSD	GDSC;CCLE	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	P38936	CDKN1A	P49841	GSK3B	S27	Q29R	29	Missense	proximal	2	no	8.454	8.250	EPSD	GDSC;CCLE	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	P38936	CDKN1A	P49841	GSK3B	S114	L119R	119	Missense	distal	5	no	6.439	7.082	PhosphoSitePlus;EPSD	GDSC;CCLE	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	O43602	DCX	P49841	GSK3B	T289	S287T	287	Missense	proximal	-2	no	7.657	7.685	EPSD	GDSC	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	P22670	RFX1	P49841	GSK3B	T253	K258N	258	Missense	distal	5	no	6.227	6.465	EPSD	GDSC	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	P08238	HSP90AB1	P49841	GSK3B	S63	P62H	62	Missense	proximal	-1	no	6.915	6.807	EPSD	GDSC;CCLE	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	P08238	HSP90AB1	P49841	GSK3B	S108	A112T	112	Missense	distal	4	no	5.099	6.641	EPSD	GDSC;CCLE	6.007	Gain
CMGC_GSK_GSK3B_ST	P08238	HSP90AB1	P49841	GSK3B	S255	E257Q	257	Missense	proximal	2	no	5.735	6.045	EPSD	GDSC;CCLE	6.007	Gain
CMGC_GSK_GSK3B_ST	P08238	HSP90AB1	P49841	GSK3B	S669	P673S	673	Missense	distal	4	no	6.872	9.843	EPSD	GDSC;CCLE	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	Q15853	USF2	P49841	GSK3B	T230	E234K	234	Missense	distal	4	no	8.881	7.699	PhosphoSitePlus;EPSD	GDSC;CCLE	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	Q15853	USF2	P49841	GSK3B	T230	P231S	231	Missense	proximal	1	no	8.881	5.036	PhosphoSitePlus;EPSD	GDSC;CCLE	6.007	Loss
CMGC_GSK_GSK3B_ST	Q07820	MCL1	P49841	GSK3B	S121	M120V	120	Missense	proximal	-1	no	7.881	7.980	EPSD;PhosphoSitePlus	GDSC	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	P24864	CCNE1	P49841	GSK3B	S103	S100C	100	Missense	distal	-3	no	7.875	7.979	EPSD	GDSC;CCLE	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	P24864	CCNE1	P49841	GSK3B	S387	L394P	394	Missense	distal	7	no	10.298	10.249	EPSD	GDSC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	P24864	CCNE1	P49841	GSK3B	S391	L394P	394	Missense	distal	3	no	6.714	7.033	EPSD	GDSC	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	P24864	CCNE1	P49841	GSK3B	T395	L394P	394	Missense	proximal	-1	no	9.736	9.868	EPSD;PhosphoSitePlus	GDSC	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	Q96F46	IL17RA	P49841	GSK3B	S561	S561N	561	Missense	central	0	yes	6.951	0.000	EPSD	GDSC;CCLE	6.007	Loss
CMGC_GSK_GSK3B_ST	Q96F46	IL17RA	P49841	GSK3B	S726	G729A	729	Missense	distal	3	no	10.550	10.169	EPSD	GDSC;CCLE	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	Q96F46	IL17RA	P49841	GSK3B	T732	G729A	729	Missense	distal	-3	no	7.850	7.874	EPSD	GDSC;CCLE	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	Q96F46	IL17RA	P49841	GSK3B	S736	P741S	741	Missense	distal	5	no	6.973	6.019	EPSD	GDSC;CCLE	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	Q96F46	IL17RA	P49841	GSK3B	S736	G729A	729	Missense	distal	-7	no	6.973	6.998	EPSD	GDSC;CCLE	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	Q96F46	IL17RA	P49841	GSK3B	S801	Q794L	794	Missense	distal	-7	no	7.580	7.565	EPSD	GDSC;CCLE	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	Q13485	SMAD4	P49841	GSK3B	S138	S144*	144	Missense	distal	6	no	6.678	6.665	EPSD	GDSC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	Q13485	SMAD4	P49841	GSK3B	S138	R135*	135	Missense	distal	-3	no	6.678	6.698	EPSD	GDSC	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	P17661	DES	P49841	GSK3B	T77	Y83H	83	Missense	distal	6	no	6.933	6.929	EPSD	GDSC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	P17661	DES	P49841	GSK3B	T77	S82T	82	Missense	distal	5	no	6.933	6.910	EPSD	GDSC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	O60346	PHLPP1	P49841	GSK3B	S336	R338C	338	Missense	proximal	2	no	6.835	6.324	EPSD	GDSC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	Q9BXF6	RAB11FIP5	P49841	GSK3B	T165	E161G	161	Missense	distal	-4	no	7.251	7.420	EPSD	GDSC;CCLE	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	Q9BXF6	RAB11FIP5	P49841	GSK3B	T165	R159L	159	Missense	distal	-6	no	7.251	7.307	EPSD	GDSC;CCLE	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	Q9BXF6	RAB11FIP5	P49841	GSK3B	S244	S251P	251	Missense	distal	7	no	6.773	6.710	EPSD	GDSC;CCLE	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	Q9BXF6	RAB11FIP5	P49841	GSK3B	T246	S251P	251	Missense	distal	5	no	6.074	7.028	EPSD	GDSC;CCLE	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	Q9BXF6	RAB11FIP5	P49841	GSK3B	T250	S251P	251	Missense	proximal	1	no	6.575	10.420	EPSD	GDSC;CCLE	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	Q9BXF6	RAB11FIP5	P49841	GSK3B	S256	S251P	251	Missense	distal	-5	no	6.295	6.139	EPSD	GDSC;CCLE	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	Q9BXF6	RAB11FIP5	P49841	GSK3B	S256	S262N	262	Missense	distal	6	no	6.295	6.289	EPSD	GDSC;CCLE	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	Q9BXF6	RAB11FIP5	P49841	GSK3B	S260	S262N	262	Missense	proximal	2	no	7.907	7.375	EPSD	GDSC;CCLE	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	Q9BXF6	RAB11FIP5	P49841	GSK3B	T276	T276P	276	Missense	central	0	yes	6.143	0.000	PhosphoSitePlus;EPSD	GDSC	6.007	Loss
CMGC_GSK_GSK3B_ST	Q9BXF6	RAB11FIP5	P49841	GSK3B	T276	G269A	269	Missense	distal	-7	no	6.143	6.168	PhosphoSitePlus;EPSD	GDSC	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	Q9BXF6	RAB11FIP5	P49841	GSK3B	S278	T276P	276	Missense	proximal	-2	no	8.421	8.650	EPSD	GDSC	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	Q9BXF6	RAB11FIP5	P49841	GSK3B	S282	T276P	276	Missense	distal	-6	no	6.182	6.261	EPSD	GDSC	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	Q9BXF6	RAB11FIP5	P49841	GSK3B	S283	T276P	276	Missense	distal	-7	no	6.743	6.714	EPSD	GDSC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	Q9BXF6	RAB11FIP5	P49841	GSK3B	S335	N339S	339	Missense	distal	4	no	3.626	7.236	EPSD	GDSC;CCLE	6.007	Gain
CMGC_GSK_GSK3B_ST	Q9BXF6	RAB11FIP5	P49841	GSK3B	S361	S364T	364	Missense	distal	3	no	8.012	7.979	EPSD	GDSC;CCLE	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	Q9BXF6	RAB11FIP5	P49841	GSK3B	S361	S357T	357	Missense	distal	-4	no	8.012	7.677	EPSD	GDSC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	Q9BXF6	RAB11FIP5	P49841	GSK3B	S494	A493V	493	Missense	proximal	-1	no	6.041	6.244	EPSD	GDSC	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	Q9BXF6	RAB11FIP5	P49841	GSK3B	S641	S641L	641	Missense	central	0	yes	6.131	0.000	EPSD	GDSC;CCLE	6.007	Loss
CMGC_GSK_GSK3B_ST	P08047	SP1	P49841	GSK3B	S59	A66G	66	Missense	distal	7	no	6.846	6.518	EPSD	GDSC;CCLE	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	P08047	SP1	P49841	GSK3B	S69	A66G	66	Missense	distal	-3	no	9.099	9.074	EPSD	GDSC;CCLE	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	P08047	SP1	P49841	GSK3B	S73	A66G	66	Missense	distal	-7	no	7.500	7.475	EPSD	GDSC;CCLE	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	P08047	SP1	P49841	GSK3B	S735	T737A	737	Missense	proximal	2	no	6.564	6.446	EPSD	GDSC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	P08047	SP1	P49841	GSK3B	S735	G736V	736	Missense	proximal	1	no	6.564	6.768	EPSD	GDSC;CCLE	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	P08047	SP1	P49841	GSK3B	S735	A738T	738	Missense	distal	3	no	6.564	6.869	EPSD	GDSC;CCLE	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	P08047	SP1	P49841	GSK3B	T737	T737A	737	Missense	central	0	yes	6.983	0.000	EPSD	GDSC	6.007	Loss
CMGC_GSK_GSK3B_ST	P08047	SP1	P49841	GSK3B	T737	G736V	736	Missense	proximal	-1	no	6.983	7.025	EPSD	GDSC;CCLE	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	P08047	SP1	P49841	GSK3B	T737	A738T	738	Missense	proximal	1	no	6.983	7.524	EPSD	GDSC;CCLE	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	P08047	SP1	P49841	GSK3B	T739	T737A	737	Missense	proximal	-2	no	7.178	6.817	EPSD	GDSC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	P08047	SP1	P49841	GSK3B	T739	G736V	736	Missense	distal	-3	no	7.178	7.350	EPSD	GDSC;CCLE	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	P08047	SP1	P49841	GSK3B	T739	A738T	738	Missense	proximal	-1	no	7.178	7.258	EPSD	GDSC;CCLE	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	P08047	SP1	P49841	GSK3B	S741	T737A	737	Missense	distal	-4	no	6.380	5.555	EPSD	GDSC	6.007	Loss
CMGC_GSK_GSK3B_ST	P08047	SP1	P49841	GSK3B	S741	G736V	736	Missense	distal	-5	no	6.380	6.493	EPSD	GDSC;CCLE	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	P08047	SP1	P49841	GSK3B	S741	A738T	738	Missense	distal	-3	no	6.380	6.384	EPSD	GDSC;CCLE	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	P31749	AKT1	P49841	GSK3B	T312	K307N	307	Missense	distal	-5	no	6.116	5.624	EPSD	GDSC;CCLE	6.007	Loss
CMGC_GSK_GSK3B_ST	P31749	AKT1	P49841	GSK3B	S473	G478S	478	Missense	distal	5	no	6.180	6.137	PhosphoSitePlus;EPSD	GDSC;CCLE	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	P04637	TP53	P49841	GSK3B	S33	Q38*	38	Missense	distal	5	no	10.252	8.224	EPSD	GDSC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	P04637	TP53	P49841	GSK3B	S127	Y126*	126	Missense	proximal	-1	no	7.079	7.010	EPSD	GDSC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	P04637	TP53	P49841	GSK3B	S127	K120*	120	Missense	distal	-7	no	7.079	7.089	EPSD	GDSC	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	P04637	TP53	P49841	GSK3B	S313	Q317*	317	Missense	distal	4	no	3.789	6.741	EPSD	GDSC	6.007	Gain
CMGC_GSK_GSK3B_ST	P04637	TP53	P49841	GSK3B	S315	K319*	319	Missense	distal	4	no	5.875	8.466	EPSD	GDSC	6.007	Gain
CMGC_GSK_GSK3B_ST	P04637	TP53	P49841	GSK3B	S362	G360V	360	Missense	proximal	-2	no	7.606	7.691	EPSD	GDSC;CCLE	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	Q14896	MYBPC3	P49841	GSK3B	T167	P161S	161	Missense	distal	-6	no	7.883	7.862	EPSD	GDSC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	Q14896	MYBPC3	P49841	GSK3B	S171	R177H	177	Missense	distal	6	no	6.348	6.342	EPSD	GDSC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	Q14896	MYBPC3	P49841	GSK3B	S175	R177H	177	Missense	proximal	2	no	6.453	6.109	EPSD	GDSC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	Q14896	MYBPC3	P49841	GSK3B	S212	A216T	216	Missense	distal	4	no	4.689	6.232	EPSD	GDSC	6.007	Gain
CMGC_GSK_GSK3B_ST	Q14896	MYBPC3	P49841	GSK3B	S311	E318*	318	Missense	distal	7	no	6.760	7.116	EPSD	GDSC	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	Q14896	MYBPC3	P49841	GSK3B	T607	V606I	606	Missense	proximal	-1	no	7.615	7.417	EPSD	GDSC;CCLE	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	Q14896	MYBPC3	P49841	GSK3B	S1067	V1063A	1063	Missense	distal	-4	no	9.012	9.086	EPSD	GDSC;CCLE	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	Q01094	E2F1	P49841	GSK3B	S307	G309E	309	Missense	proximal	2	no	8.116	8.287	EPSD	GDSC;CCLE	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	Q01094	E2F1	P49841	GSK3B	T311	G309E	309	Missense	proximal	-2	no	7.138	7.153	EPSD	GDSC;CCLE	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	Q01094	E2F1	P49841	GSK3B	S313	G309E	309	Missense	distal	-4	no	6.819	6.650	EPSD	GDSC;CCLE	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	Q01094	E2F1	P49841	GSK3B	S352	P357Q	357	Missense	distal	5	no	6.413	5.437	EPSD	GDSC	6.007	Loss
CMGC_GSK_GSK3B_ST	Q01094	E2F1	P49841	GSK3B	S352	L351V	351	Missense	proximal	-1	no	6.413	6.537	EPSD	GDSC;CCLE	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	Q01094	E2F1	P49841	GSK3B	S352	S349Y	349	Missense	distal	-3	no	6.413	6.554	EPSD	GDSC;CCLE	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	Q01094	E2F1	P49841	GSK3B	S403	A408T	408	Missense	distal	5	no	9.524	9.576	EPSD;PhosphoSitePlus	GDSC;CCLE	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	Q15746	MYLK	P49841	GSK3B	S18	S13Y	13	Missense	distal	-5	no	8.033	8.685	EPSD	GDSC;CCLE	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	Q15746	MYLK	P49841	GSK3B	T335	P336L	336	Missense	proximal	1	no	6.367	3.506	EPSD	GDSC	6.007	Loss
CMGC_GSK_GSK3B_ST	Q15746	MYLK	P49841	GSK3B	S947	R954H	954	Missense	distal	7	no	7.383	7.571	EPSD	GDSC;CCLE	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	Q15746	MYLK	P49841	GSK3B	S1093	S1093I	1093	Missense	central	0	yes	6.013	0.000	EPSD	GDSC;CCLE	6.007	Loss
CMGC_GSK_GSK3B_ST	Q15746	MYLK	P49841	GSK3B	S1093	P1098S	1098	Missense	distal	5	no	6.013	5.059	EPSD	GDSC;CCLE	6.007	Loss
CMGC_GSK_GSK3B_ST	Q15746	MYLK	P49841	GSK3B	S1419	E1414K	1414	Missense	distal	-5	no	6.665	6.435	EPSD	GDSC;CCLE	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	Q15746	MYLK	P49841	GSK3B	S1772	G1775E	1775	Missense	distal	3	no	8.059	7.996	EPSD	GDSC;CCLE	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	Q15746	MYLK	P49841	GSK3B	S1772	L1767P	1767	Missense	distal	-5	no	8.059	7.794	EPSD	GDSC;CCLE	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	Q15746	MYLK	P49841	GSK3B	S1772	S1776P	1776	Missense	distal	4	no	8.059	5.088	EPSD	GDSC;CCLE	6.007	Loss
CMGC_GSK_GSK3B_ST	Q15746	MYLK	P49841	GSK3B	T1774	S1776P	1776	Missense	proximal	2	no	5.949	6.393	EPSD	GDSC;CCLE	6.007	Gain
CMGC_GSK_GSK3B_ST	Q15746	MYLK	P49841	GSK3B	S1776	G1775E	1775	Missense	proximal	-1	no	8.990	8.971	PhosphoSitePlus	GDSC;CCLE	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	Q15746	MYLK	P49841	GSK3B	S1776	S1776P	1776	Missense	central	0	yes	8.990	0.000	PhosphoSitePlus	GDSC;CCLE	6.007	Loss
CMGC_GSK_GSK3B_ST	Q15746	MYLK	P49841	GSK3B	S1779	G1775E	1775	Missense	distal	-4	no	8.264	8.095	EPSD	GDSC;CCLE	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	Q15746	MYLK	P49841	GSK3B	S1779	L1786I	1786	Missense	distal	7	no	8.264	8.614	EPSD	GDSC	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	Q15746	MYLK	P49841	GSK3B	S1779	S1776P	1776	Missense	distal	-3	no	8.264	8.147	EPSD	GDSC;CCLE	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	P20393	NR1D1	P49841	GSK3B	S59	D63H	63	Missense	distal	4	no	6.607	5.275	EPSD;PhosphoSitePlus	GDSC;CCLE	6.007	Loss
CMGC_GSK_GSK3B_ST	P20393	NR1D1	P49841	GSK3B	S59	R66P	66	Missense	distal	7	no	6.607	6.106	EPSD;PhosphoSitePlus	GDSC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	P20393	NR1D1	P49841	GSK3B	S322	A319V	319	Missense	distal	-3	no	9.126	9.272	EPSD	GDSC	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	P20393	NR1D1	P49841	GSK3B	S322	N315S	315	Missense	distal	-7	no	9.126	9.120	EPSD	GDSC;CCLE	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	Q9NYF8	BCLAF1	P49841	GSK3B	S6	S11*	11	Missense	distal	5	no	7.649	5.599	EPSD	GDSC	6.007	Loss
CMGC_GSK_GSK3B_ST	Q9NYF8	BCLAF1	P49841	GSK3B	S6	N5K	5	Missense	proximal	-1	no	7.649	7.643	EPSD	GDSC;CCLE	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	Q9NYF8	BCLAF1	P49841	GSK3B	S15	S11*	11	Missense	distal	-4	no	7.933	6.583	EPSD	GDSC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	Q9NYF8	BCLAF1	P49841	GSK3B	S46	M52I	52	Missense	distal	6	no	6.579	6.584	EPSD	GDSC;CCLE	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	Q9NYF8	BCLAF1	P49841	GSK3B	S48	M52I	52	Missense	distal	4	no	6.141	5.054	EPSD	GDSC;CCLE	6.007	Loss
CMGC_GSK_GSK3B_ST	Q9NYF8	BCLAF1	P49841	GSK3B	S54	M52I	52	Missense	proximal	-2	no	6.057	6.378	EPSD	GDSC;CCLE	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	Q9NYF8	BCLAF1	P49841	GSK3B	S104	R107*	107	Missense	distal	3	no	7.978	8.081	EPSD	GDSC	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	Q9NYF8	BCLAF1	P49841	GSK3B	S104	R107Q	107	Missense	distal	3	no	7.978	8.312	EPSD	GDSC	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	Q9NYF8	BCLAF1	P49841	GSK3B	S114	R107*	107	Missense	distal	-7	no	7.790	7.802	EPSD	GDSC	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	Q9NYF8	BCLAF1	P49841	GSK3B	S114	S112F	112	Missense	proximal	-2	no	7.790	7.459	EPSD	GDSC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	Q9NYF8	BCLAF1	P49841	GSK3B	S114	S121P	121	Missense	distal	7	no	7.790	7.726	EPSD	GDSC;CCLE	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	Q9NYF8	BCLAF1	P49841	GSK3B	S114	R107Q	107	Missense	distal	-7	no	7.790	7.786	EPSD	GDSC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	Q9NYF8	BCLAF1	P49841	GSK3B	S114	R117S	117	Missense	distal	3	no	7.790	8.160	EPSD	GDSC	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	Q9NYF8	BCLAF1	P49841	GSK3B	S114	R117T	117	Missense	distal	3	no	7.790	8.128	EPSD	GDSC	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	Q9NYF8	BCLAF1	P49841	GSK3B	S114	R113S	113	Missense	proximal	-1	no	7.790	7.927	EPSD	GDSC;CCLE	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	Q9NYF8	BCLAF1	P49841	GSK3B	S114	R113M	113	Missense	proximal	-1	no	7.790	7.876	EPSD	GDSC;CCLE	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	Q9NYF8	BCLAF1	P49841	GSK3B	S121	S121P	121	Missense	central	0	yes	7.333	0.000	EPSD	GDSC;CCLE	6.007	Loss
CMGC_GSK_GSK3B_ST	Q9NYF8	BCLAF1	P49841	GSK3B	S121	R117S	117	Missense	distal	-4	no	7.333	8.520	EPSD	GDSC	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	Q9NYF8	BCLAF1	P49841	GSK3B	S121	R117T	117	Missense	distal	-4	no	7.333	8.185	EPSD	GDSC	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	Q9NYF8	BCLAF1	P49841	GSK3B	S125	S121P	121	Missense	distal	-4	no	8.877	8.314	EPSD	GDSC;CCLE	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	Q9NYF8	BCLAF1	P49841	GSK3B	S125	S129Y	129	Missense	distal	4	no	8.877	5.364	EPSD	GDSC;CCLE	6.007	Loss
CMGC_GSK_GSK3B_ST	Q9NYF8	BCLAF1	P49841	GSK3B	S136	S143Y	143	Missense	distal	7	no	5.943	6.385	EPSD	GDSC;CCLE	6.007	Gain
CMGC_GSK_GSK3B_ST	Q9NYF8	BCLAF1	P49841	GSK3B	S138	S143Y	143	Missense	distal	5	no	10.710	9.711	EPSD	GDSC;CCLE	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	Q9NYF8	BCLAF1	P49841	GSK3B	S142	S143Y	143	Missense	proximal	1	no	5.663	6.190	EPSD	GDSC;CCLE	6.007	Gain
CMGC_GSK_GSK3B_ST	Q9NYF8	BCLAF1	P49841	GSK3B	S143	S143Y	143	Missense	central	0	yes	6.597	0.000	EPSD	GDSC;CCLE	6.007	Loss
CMGC_GSK_GSK3B_ST	Q9NYF8	BCLAF1	P49841	GSK3B	S147	P149T	149	Missense	proximal	2	no	6.286	5.968	EPSD	GDSC	6.007	Loss
CMGC_GSK_GSK3B_ST	Q9NYF8	BCLAF1	P49841	GSK3B	S147	S143Y	143	Missense	distal	-4	no	6.286	5.485	EPSD	GDSC;CCLE	6.007	Loss
CMGC_GSK_GSK3B_ST	Q9NYF8	BCLAF1	P49841	GSK3B	S148	P149T	149	Missense	proximal	1	no	7.086	3.895	EPSD	GDSC	6.007	Loss
CMGC_GSK_GSK3B_ST	Q9NYF8	BCLAF1	P49841	GSK3B	S148	S143Y	143	Missense	distal	-5	no	7.086	7.738	EPSD	GDSC;CCLE	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	Q9NYF8	BCLAF1	P49841	GSK3B	S153	P149T	149	Missense	distal	-4	no	7.955	8.182	EPSD	GDSC	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	Q9NYF8	BCLAF1	P49841	GSK3B	S177	E176*	176	Missense	proximal	-1	no	10.456	10.259	EPSD	GDSC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	Q9NYF8	BCLAF1	P49841	GSK3B	S177	E175K	175	Missense	proximal	-2	no	10.456	10.425	EPSD	GDSC;CCLE	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	Q9NYF8	BCLAF1	P49841	GSK3B	S205	G210D	210	Missense	distal	5	no	6.387	6.450	EPSD	GDSC	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	Q9NYF8	BCLAF1	P49841	GSK3B	S205	S206P	206	Missense	proximal	1	no	6.387	10.231	EPSD	GDSC	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	Q9NYF8	BCLAF1	P49841	GSK3B	S230	P236R	236	Missense	distal	6	no	8.932	8.926	EPSD	GDSC;CCLE	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	Q9NYF8	BCLAF1	P49841	GSK3B	S239	A245V	245	Missense	distal	6	no	6.553	6.545	EPSD	GDSC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	Q9NYF8	BCLAF1	P49841	GSK3B	S239	P236R	236	Missense	distal	-3	no	6.553	6.839	EPSD	GDSC;CCLE	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	Q9NYF8	BCLAF1	P49841	GSK3B	S249	V251A	251	Missense	proximal	2	no	7.274	7.551	EPSD	GDSC;CCLE	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	Q9NYF8	BCLAF1	P49841	GSK3B	S249	A245V	245	Missense	distal	-4	no	7.274	7.200	EPSD	GDSC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	Q9NYF8	BCLAF1	P49841	GSK3B	S249	A254S	254	Missense	distal	5	no	7.274	7.349	EPSD	GDSC;CCLE	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	Q9NYF8	BCLAF1	P49841	GSK3B	S249	T250R	250	Missense	proximal	1	no	7.274	8.145	EPSD	GDSC	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	Q9NYF8	BCLAF1	P49841	GSK3B	S253	V251A	251	Missense	proximal	-2	no	7.196	6.894	EPSD	GDSC;CCLE	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	Q9NYF8	BCLAF1	P49841	GSK3B	S253	A254S	254	Missense	proximal	1	no	7.196	7.084	EPSD	GDSC;CCLE	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	Q9NYF8	BCLAF1	P49841	GSK3B	S253	T250R	250	Missense	distal	-3	no	7.196	7.340	EPSD	GDSC	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	Q9NYF8	BCLAF1	P49841	GSK3B	S264	H267R	267	Missense	distal	3	no	7.837	7.495	EPSD	GDSC;CCLE	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	Q9NYF8	BCLAF1	P49841	GSK3B	S268	G275D	275	Missense	distal	7	no	8.909	8.943	EPSD	GDSC	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	Q9NYF8	BCLAF1	P49841	GSK3B	S268	H267R	267	Missense	proximal	-1	no	8.909	8.823	EPSD	GDSC;CCLE	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	Q9NYF8	BCLAF1	P49841	GSK3B	S272	G275D	275	Missense	distal	3	no	7.067	7.119	EPSD	GDSC	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	Q9NYF8	BCLAF1	P49841	GSK3B	S272	H267R	267	Missense	distal	-5	no	7.067	7.598	EPSD	GDSC;CCLE	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	Q9NYF8	BCLAF1	P49841	GSK3B	S276	S281P	281	Missense	distal	5	no	5.515	6.469	EPSD	GDSC;CCLE	6.007	Gain
CMGC_GSK_GSK3B_ST	Q9NYF8	BCLAF1	P49841	GSK3B	S281	G275D	275	Missense	distal	-6	no	6.424	6.383	EPSD	GDSC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	Q9NYF8	BCLAF1	P49841	GSK3B	S281	S281P	281	Missense	central	0	yes	6.424	0.000	EPSD	GDSC;CCLE	6.007	Loss
CMGC_GSK_GSK3B_ST	Q9NYF8	BCLAF1	P49841	GSK3B	S281	Q288H	288	Missense	distal	7	no	6.424	6.960	EPSD	GDSC;CCLE	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	Q9NYF8	BCLAF1	P49841	GSK3B	S285	N289S	289	Missense	distal	4	no	7.515	11.125	EPSD	GDSC;CCLE	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	Q9NYF8	BCLAF1	P49841	GSK3B	S285	S281P	281	Missense	distal	-4	no	7.515	6.951	EPSD	GDSC;CCLE	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	Q9NYF8	BCLAF1	P49841	GSK3B	S285	Q288H	288	Missense	distal	3	no	7.515	7.524	EPSD	GDSC;CCLE	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	Q9NYF8	BCLAF1	P49841	GSK3B	S300	A302E	302	Missense	proximal	2	no	8.714	8.619	EPSD	GDSC;CCLE	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	Q9NYF8	BCLAF1	P49841	GSK3B	S300	R298*	298	Missense	proximal	-2	no	8.714	8.195	EPSD	GDSC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	Q9NYF8	BCLAF1	P49841	GSK3B	S315	R316S	316	Missense	proximal	1	no	8.876	7.351	EPSD	GDSC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	Q9NYF8	BCLAF1	P49841	GSK3B	S315	R316M	316	Missense	proximal	1	no	8.876	7.609	EPSD	GDSC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	Q9NYF8	BCLAF1	P49841	GSK3B	T355	E359*	359	Missense	distal	4	no	5.634	7.043	EPSD	GDSC	6.007	Gain
CMGC_GSK_GSK3B_ST	Q9NYF8	BCLAF1	P49841	GSK3B	S385	S385G	385	Missense	central	0	yes	6.855	0.000	EPSD	GDSC	6.007	Loss
CMGC_GSK_GSK3B_ST	Q9NYF8	BCLAF1	P49841	GSK3B	S485	E486G	486	Missense	proximal	1	no	5.951	6.590	EPSD	GDSC;CCLE	6.007	Gain
CMGC_GSK_GSK3B_ST	Q9NYF8	BCLAF1	P49841	GSK3B	S512	L515I	515	Missense	distal	3	no	6.049	5.929	EPSD	GDSC;CCLE	6.007	Loss
CMGC_GSK_GSK3B_ST	Q9NYF8	BCLAF1	P49841	GSK3B	S512	D507E	507	Missense	distal	-5	no	6.049	6.207	EPSD	GDSC	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	Q9NYF8	BCLAF1	P49841	GSK3B	S512	P514L	514	Missense	proximal	2	no	6.049	5.665	EPSD	GDSC;CCLE	6.007	Loss
CMGC_GSK_GSK3B_ST	Q9NYF8	BCLAF1	P49841	GSK3B	T644	I651M	651	Missense	distal	7	no	9.401	9.434	EPSD	GDSC;CCLE	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	Q9NYF8	BCLAF1	P49841	GSK3B	S658	R654S	654	Missense	distal	-4	no	8.786	9.973	EPSD	GDSC;CCLE	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	Q9NYF8	BCLAF1	P49841	GSK3B	S658	I651M	651	Missense	distal	-7	no	8.786	8.779	EPSD	GDSC;CCLE	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	Q9NYF8	BCLAF1	P49841	GSK3B	S714	R708Q	708	Missense	distal	-6	no	8.636	8.689	EPSD	GDSC	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	Q9NYF8	BCLAF1	P49841	GSK3B	S749	S749C	749	Missense	central	0	yes	7.933	0.000	EPSD	GDSC;CCLE	6.007	Loss
CMGC_GSK_GSK3B_ST	Q9NYF8	BCLAF1	P49841	GSK3B	S751	P758S	758	Missense	distal	7	no	7.694	7.758	EPSD	GDSC	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	Q9NYF8	BCLAF1	P49841	GSK3B	S751	S749C	749	Missense	proximal	-2	no	7.694	7.383	EPSD	GDSC;CCLE	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	Q9NYF8	BCLAF1	P49841	GSK3B	S755	P758S	758	Missense	distal	3	no	7.502	7.484	EPSD	GDSC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	Q9NYF8	BCLAF1	P49841	GSK3B	S755	S749C	749	Missense	distal	-6	no	7.502	7.491	EPSD	GDSC;CCLE	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	Q9NYF8	BCLAF1	P49841	GSK3B	S757	P758S	758	Missense	proximal	1	no	8.512	4.668	EPSD	GDSC	6.007	Loss
CMGC_GSK_GSK3B_ST	Q9NYF8	BCLAF1	P49841	GSK3B	S759	P758S	758	Missense	proximal	-1	no	7.745	7.689	EPSD	GDSC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	Q9NYF8	BCLAF1	P49841	GSK3B	S760	P758S	758	Missense	proximal	-2	no	7.612	7.356	EPSD	GDSC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	Q9NYF8	BCLAF1	P49841	GSK3B	S884	D890E	890	Missense	distal	6	no	8.318	8.320	EPSD	GDSC	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	O75030	MITF	P49841	GSK3B	S176	P178R	178	Missense	proximal	2	no	6.901	6.475	EPSD	GDSC;CCLE	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	O75030	MITF	P49841	GSK3B	S180	P178R	178	Missense	proximal	-2	no	8.658	8.287	EPSD	GDSC;CCLE	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	P48436	SOX9	P49841	GSK3B	S37	D42N	42	Missense	distal	5	no	8.222	7.796	EPSD	GDSC;CCLE	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	P48436	SOX9	P49841	GSK3B	S211	H213Q	213	Missense	proximal	2	no	8.253	8.801	EPSD	GDSC;CCLE	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	P48436	SOX9	P49841	GSK3B	S215	H213Q	213	Missense	proximal	-2	no	7.687	7.748	EPSD	GDSC;CCLE	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	P48436	SOX9	P49841	GSK3B	S219	H213Q	213	Missense	distal	-6	no	6.894	6.924	EPSD	GDSC;CCLE	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	P48436	SOX9	P49841	GSK3B	T239	Q246P	246	Missense	distal	7	no	6.312	6.159	EPSD	GDSC;CCLE	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	P48436	SOX9	P49841	GSK3B	S494	P501A	501	Missense	distal	7	no	7.457	7.868	EPSD	GDSC;CCLE	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	P06401	PGR	P49841	GSK3B	S130	C134*	134	Missense	distal	4	no	5.207	10.728	EPSD	GDSC	6.007	Gain
CMGC_GSK_GSK3B_ST	P06401	PGR	P49841	GSK3B	S162	R167Q	167	Missense	distal	5	no	11.146	10.807	EPSD	GDSC;CCLE	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	P06401	PGR	P49841	GSK3B	S273	F275S	275	Missense	proximal	2	no	6.161	6.505	EPSD	GDSC;CCLE	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	P06401	PGR	P49841	GSK3B	S345	A338P	338	Missense	distal	-7	no	9.402	9.378	EPSD	GDSC;CCLE	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	P06401	PGR	P49841	GSK3B	S345	P342L	342	Missense	distal	-3	no	9.402	9.529	EPSD	GDSC;CCLE	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	O75952	CABYR	P49841	GSK3B	T120	F122S	122	Missense	proximal	2	no	7.066	7.411	EPSD	GDSC	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	O75952	CABYR	P49841	GSK3B	S211	A215S	215	Missense	distal	4	no	4.004	6.416	EPSD	GDSC	6.007	Gain
CMGC_GSK_GSK3B_ST	O75952	CABYR	P49841	GSK3B	S339	S339P	339	Missense	central	0	yes	10.741	0.000	EPSD	GDSC	6.007	Loss
CMGC_GSK_GSK3B_ST	O75952	CABYR	P49841	GSK3B	S339	S333Y	333	Missense	distal	-6	no	10.741	10.655	EPSD	GDSC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	O75952	CABYR	P49841	GSK3B	S343	S339P	339	Missense	distal	-4	no	7.555	6.992	EPSD	GDSC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	Q01518	CAP1	P49841	GSK3B	S34	P35L	35	Missense	proximal	1	no	9.154	6.294	EPSD	GDSC;CCLE	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	Q01518	CAP1	P49841	GSK3B	S255	A259S	259	Missense	distal	4	no	4.799	7.210	EPSD	GDSC;CCLE	6.007	Gain
CMGC_GSK_GSK3B_ST	P04150	NR3C1	P49841	GSK3B	S79	M86V	86	Missense	distal	7	no	6.608	6.665	EPSD	GDSC	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	Q00613	HSF1	P49841	GSK3B	S292	R296H	296	Missense	distal	4	no	7.295	6.576	EPSD	GDSC;CCLE	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	Q00613	HSF1	P49841	GSK3B	S303	P308L	308	Missense	distal	5	no	13.157	11.876	PhosphoSitePlus	GDSC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	Q00613	HSF1	P49841	GSK3B	S307	P308L	308	Missense	proximal	1	no	8.879	6.018	EPSD	GDSC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	Q00613	HSF1	P49841	GSK3B	S307	E312A	312	Missense	distal	5	no	8.879	8.495	EPSD	GDSC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	Q00613	HSF1	P49841	GSK3B	S314	P308L	308	Missense	distal	-6	no	6.674	6.652	EPSD	GDSC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	Q00613	HSF1	P49841	GSK3B	S314	E312A	312	Missense	proximal	-2	no	6.674	6.442	EPSD	GDSC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	Q00613	HSF1	P49841	GSK3B	S344	V345I	345	Missense	proximal	1	no	6.021	5.131	EPSD	GDSC	6.007	Loss
CMGC_GSK_GSK3B_ST	Q00613	HSF1	P49841	GSK3B	S363	R360Q	360	Missense	distal	-3	no	11.390	11.251	EPSD	GDSC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	Q00613	HSF1	P49841	GSK3B	S363	R360W	360	Missense	distal	-3	no	11.390	11.320	EPSD	GDSC;CCLE	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	Q00613	HSF1	P49841	GSK3B	S419	S419R	419	Missense	central	0	yes	7.800	0.000	EPSD	GDSC	6.007	Loss
CMGC_GSK_GSK3B_ST	Q00613	HSF1	P49841	GSK3B	S419	S421W	421	Missense	proximal	2	no	7.800	7.388	EPSD	GDSC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	Q00613	HSF1	P49841	GSK3B	S419	V422L	422	Missense	distal	3	no	7.800	7.707	EPSD	GDSC;CCLE	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	Q00613	HSF1	P49841	GSK3B	S457	S458I	458	Missense	proximal	1	no	6.497	6.461	EPSD	GDSC;CCLE	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	Q00613	HSF1	P49841	GSK3B	S458	S458I	458	Missense	central	0	yes	6.430	0.000	EPSD	GDSC;CCLE	6.007	Loss
CMGC_GSK_GSK3B_ST	Q9HB09	BCL2L12	P49841	GSK3B	S156	S149Y	149	Missense	distal	-7	no	6.428	6.456	PhosphoSitePlus	GDSC;CCLE	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	Q9HB09	BCL2L12	P49841	GSK3B	S273	P270S	270	Missense	distal	-3	no	8.561	8.678	EPSD	GDSC;CCLE	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	O75581	LRP6	P49841	GSK3B	T420	Y418H	418	Missense	proximal	-2	no	6.201	6.415	EPSD	GDSC	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	O75581	LRP6	P49841	GSK3B	S1473	T1479I	1479	Missense	distal	6	no	7.015	7.012	EPSD	GDSC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	O75581	LRP6	P49841	GSK3B	S1475	T1479I	1479	Missense	distal	4	no	6.420	3.967	EPSD	GDSC	6.007	Loss
CMGC_GSK_GSK3B_ST	O75581	LRP6	P49841	GSK3B	S1490	R1495Q	1495	Missense	distal	5	no	9.049	8.710	PhosphoSitePlus	GDSC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	O75581	LRP6	P49841	GSK3B	S1607	S1612F	1612	Missense	distal	5	no	8.861	8.194	EPSD	GDSC;CCLE	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	Q6R327	RICTOR	P49841	GSK3B	T31	R32L	32	Missense	proximal	1	no	6.382	5.841	EPSD	GDSC;CCLE	6.007	Loss
CMGC_GSK_GSK3B_ST	Q6R327	RICTOR	P49841	GSK3B	S1026	H1033Y	1033	Missense	distal	7	no	6.716	6.533	EPSD	GDSC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	Q6R327	RICTOR	P49841	GSK3B	S1031	H1033Y	1033	Missense	proximal	2	no	8.808	8.901	EPSD	GDSC	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	Q6R327	RICTOR	P49841	GSK3B	S1039	H1033Y	1033	Missense	distal	-6	no	7.585	7.532	EPSD	GDSC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	Q6R327	RICTOR	P49841	GSK3B	T1148	Q1154P	1154	Missense	distal	6	no	7.539	7.545	EPSD	GDSC;CCLE	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	Q6R327	RICTOR	P49841	GSK3B	T1152	Q1154P	1154	Missense	proximal	2	no	7.207	7.429	EPSD	GDSC;CCLE	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	Q6R327	RICTOR	P49841	GSK3B	T1152	L1159V	1159	Missense	distal	7	no	7.207	7.647	EPSD	GDSC;CCLE	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	Q6R327	RICTOR	P49841	GSK3B	S1235	G1242D	1242	Missense	distal	7	no	9.254	9.289	EPSD;PhosphoSitePlus	GDSC;CCLE	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	Q6R327	RICTOR	P49841	GSK3B	S1411	R1405*	1405	Missense	distal	-6	no	7.061	7.055	EPSD	GDSC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	P35612	ADD2	P49841	GSK3B	S60	P61L	61	Missense	proximal	1	no	6.927	4.066	EPSD	GDSC	6.007	Loss
CMGC_GSK_GSK3B_ST	P35612	ADD2	P49841	GSK3B	S455	P456S	456	Missense	proximal	1	no	6.726	2.881	EPSD	GDSC;CCLE	6.007	Loss
CMGC_GSK_GSK3B_ST	P35612	ADD2	P49841	GSK3B	S471	S472R	472	Missense	proximal	1	no	5.243	6.768	EPSD	GDSC;CCLE	6.007	Gain
CMGC_GSK_GSK3B_ST	P35612	ADD2	P49841	GSK3B	S667	S667N	667	Missense	central	0	yes	6.656	0.000	EPSD	GDSC;CCLE	6.007	Loss
CMGC_GSK_GSK3B_ST	P35612	ADD2	P49841	GSK3B	T671	S667N	667	Missense	distal	-4	no	6.090	4.793	EPSD	GDSC;CCLE	6.007	Loss
CMGC_GSK_GSK3B_ST	Q15691	MAPRE1	P49841	GSK3B	S165	R162K	162	Missense	distal	-3	no	6.685	6.540	EPSD	GDSC;CCLE	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	P25054	APC	P49841	GSK3B	S111	M115V	115	Missense	distal	4	no	8.187	8.031	EPSD	GDSC;CCLE	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	P25054	APC	P49841	GSK3B	S127	L134S	134	Missense	distal	7	no	6.184	6.198	EPSD	GDSC;CCLE	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	P25054	APC	P49841	GSK3B	S1100	Q1096*	1096	Missense	distal	-4	no	9.022	8.501	EPSD	GDSC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	P25054	APC	P49841	GSK3B	S1148	Q1152*	1152	Missense	distal	4	no	3.526	6.478	EPSD	GDSC	6.007	Gain
CMGC_GSK_GSK3B_ST	P25054	APC	P49841	GSK3B	S1214	M1211I	1211	Missense	distal	-3	no	5.884	6.026	EPSD	GDSC;CCLE	6.007	Gain
CMGC_GSK_GSK3B_ST	P25054	APC	P49841	GSK3B	T1218	S1213P	1213	Missense	distal	-5	no	6.412	6.255	EPSD	GDSC;CCLE	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	P25054	APC	P49841	GSK3B	T1218	A1225S	1225	Missense	distal	7	no	6.412	6.064	EPSD	GDSC;CCLE	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	P25054	APC	P49841	GSK3B	T1218	M1211I	1211	Missense	distal	-7	no	6.412	6.418	EPSD	GDSC;CCLE	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	P25054	APC	P49841	GSK3B	T1218	E1216K	1216	Missense	proximal	-2	no	6.412	6.380	EPSD	GDSC;CCLE	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	P25054	APC	P49841	GSK3B	S1219	S1213P	1213	Missense	distal	-6	no	6.651	6.672	EPSD	GDSC;CCLE	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	P25054	APC	P49841	GSK3B	S1219	A1225S	1225	Missense	distal	6	no	6.651	6.652	EPSD	GDSC;CCLE	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	P25054	APC	P49841	GSK3B	S1219	E1216K	1216	Missense	distal	-3	no	6.651	6.661	EPSD	GDSC;CCLE	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	P25054	APC	P49841	GSK3B	S1272	C1270R	1270	Missense	proximal	-2	no	6.638	6.834	EPSD	GDSC;CCLE	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	P25054	APC	P49841	GSK3B	T1313	E1317*	1317	Missense	distal	4	no	5.209	6.618	EPSD	GDSC	6.007	Gain
CMGC_GSK_GSK3B_ST	P25054	APC	P49841	GSK3B	S1360	Q1367*	1367	Missense	distal	7	no	10.460	10.766	EPSD	GDSC	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	P25054	APC	P49841	GSK3B	S1364	Q1367*	1367	Missense	distal	3	no	7.800	7.570	EPSD	GDSC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	P25054	APC	P49841	GSK3B	T1368	Q1367*	1367	Missense	proximal	-1	no	7.906	7.803	EPSD	GDSC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	P25054	APC	P49841	GSK3B	S1371	Q1367*	1367	Missense	distal	-4	no	6.484	5.963	EPSD	GDSC	6.007	Loss
CMGC_GSK_GSK3B_ST	P25054	APC	P49841	GSK3B	S1385	S1392*	1392	Missense	distal	7	no	6.310	6.706	EPSD	GDSC	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	P25054	APC	P49841	GSK3B	S1426	Q1429*	1429	Missense	distal	3	no	7.675	7.445	EPSD	GDSC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	P25054	APC	P49841	GSK3B	S1501	G1499*	1499	Missense	proximal	-2	no	8.486	7.970	EPSD;PhosphoSitePlus	GDSC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	P25054	APC	P49841	GSK3B	S1503	G1499*	1499	Missense	distal	-4	no	6.247	5.324	PhosphoSitePlus;EPSD	GDSC	6.007	Loss
CMGC_GSK_GSK3B_ST	P25054	APC	P49841	GSK3B	T1633	D1636Y	1636	Missense	distal	3	no	6.346	5.829	EPSD	GDSC;CCLE	6.007	Loss
CMGC_GSK_GSK3B_ST	P25054	APC	P49841	GSK3B	S2022	S2028T	2028	Missense	distal	6	no	6.546	6.548	EPSD	GDSC;CCLE	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	P25054	APC	P49841	GSK3B	S2146	L2150V	2150	Missense	distal	4	no	5.695	6.023	EPSD	GDSC;CCLE	6.007	Gain
CMGC_GSK_GSK3B_ST	P25054	APC	P49841	GSK3B	T2243	K2248*	2248	Missense	distal	5	no	6.497	5.005	EPSD	GDSC	6.007	Loss
CMGC_GSK_GSK3B_ST	P25054	APC	P49841	GSK3B	S2244	K2248*	2248	Missense	distal	4	no	5.821	8.411	EPSD	GDSC	6.007	Gain
CMGC_GSK_GSK3B_ST	P25054	APC	P49841	GSK3B	T2255	K2248*	2248	Missense	distal	-7	no	6.155	6.164	EPSD	GDSC	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	P25054	APC	P49841	GSK3B	T2255	S2262N	2262	Missense	distal	7	no	6.155	6.277	EPSD	GDSC;CCLE	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	P25054	APC	P49841	GSK3B	S2258	S2262N	2262	Missense	distal	4	no	7.079	3.469	EPSD	GDSC;CCLE	6.007	Loss
CMGC_GSK_GSK3B_ST	P25054	APC	P49841	GSK3B	S2260	S2262N	2262	Missense	proximal	2	no	6.088	5.556	EPSD	GDSC;CCLE	6.007	Loss
CMGC_GSK_GSK3B_ST	P25054	APC	P49841	GSK3B	S2337	L2342F	2342	Missense	distal	5	no	7.677	7.336	EPSD	GDSC;CCLE	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	P25054	APC	P49841	GSK3B	S2337	R2333K	2333	Missense	distal	-4	no	7.677	7.999	EPSD	GDSC;CCLE	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	P25054	APC	P49841	GSK3B	T2348	L2342F	2342	Missense	distal	-6	no	6.595	6.543	EPSD	GDSC;CCLE	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	P25054	APC	P49841	GSK3B	S2449	P2448S	2448	Missense	proximal	-1	no	6.896	6.839	EPSD	GDSC;CCLE	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	P25054	APC	P49841	GSK3B	S2464	F2462S	2462	Missense	proximal	-2	no	6.799	7.130	EPSD	GDSC;CCLE	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	P25054	APC	P49841	GSK3B	S2464	P2467L	2467	Missense	distal	3	no	6.799	6.481	EPSD	GDSC;CCLE	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	P25054	APC	P49841	GSK3B	S2466	F2462S	2462	Missense	distal	-4	no	7.295	8.449	EPSD	GDSC;CCLE	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	P25054	APC	P49841	GSK3B	S2466	P2467L	2467	Missense	proximal	1	no	7.295	4.434	EPSD	GDSC;CCLE	6.007	Loss
CMGC_GSK_GSK3B_ST	P25054	APC	P49841	GSK3B	S2469	F2462S	2462	Missense	distal	-7	no	7.641	7.631	EPSD	GDSC;CCLE	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	P25054	APC	P49841	GSK3B	S2469	P2467L	2467	Missense	proximal	-2	no	7.641	7.311	EPSD	GDSC;CCLE	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	P25054	APC	P49841	GSK3B	S2473	P2467L	2467	Missense	distal	-6	no	10.333	10.311	EPSD	GDSC;CCLE	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	P25054	APC	P49841	GSK3B	T2563	V2561L	2561	Missense	proximal	-2	no	7.337	7.296	EPSD	GDSC;CCLE	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	P25054	APC	P49841	GSK3B	S2621	S2625I	2625	Missense	distal	4	no	9.358	6.036	EPSD	GDSC;CCLE	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	P25054	APC	P49841	GSK3B	S2621	E2617V	2617	Missense	distal	-4	no	9.358	8.722	EPSD	GDSC;CCLE	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	P25054	APC	P49841	GSK3B	S2625	S2625I	2625	Missense	central	0	yes	6.567	0.000	EPSD	GDSC;CCLE	6.007	Loss
CMGC_GSK_GSK3B_ST	P25054	APC	P49841	GSK3B	S2627	S2625I	2625	Missense	proximal	-2	no	7.373	7.363	EPSD	GDSC;CCLE	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	P25054	APC	P49841	GSK3B	T2679	V2686A	2686	Missense	distal	7	no	6.363	6.286	EPSD	GDSC;CCLE	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	P25054	APC	P49841	GSK3B	T2679	R2673G	2673	Missense	distal	-6	no	6.363	6.437	EPSD	GDSC;CCLE	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	P25054	APC	P49841	GSK3B	S2772	A2778V	2778	Missense	distal	6	no	9.633	9.625	EPSD	GDSC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	P25054	APC	P49841	GSK3B	S2830	H2834Y	2834	Missense	distal	4	no	6.059	6.302	EPSD	GDSC;CCLE	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	P25054	APC	P49841	GSK3B	S2837	H2834Y	2834	Missense	distal	-3	no	6.032	6.061	EPSD	GDSC;CCLE	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	Q99626	CDX2	P49841	GSK3B	S283	V285M	285	Missense	proximal	2	no	10.073	9.771	PhosphoSitePlus	GDSC;CCLE	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	Q99626	CDX2	P49841	GSK3B	S287	V285M	285	Missense	proximal	-2	no	7.105	6.806	EPSD	GDSC;CCLE	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	Q99626	CDX2	P49841	GSK3B	S291	V285M	285	Missense	distal	-6	no	7.019	7.033	EPSD	GDSC;CCLE	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	P30291	WEE1	P49841	GSK3B	S289	N290S	290	Missense	proximal	1	no	5.418	7.093	EPSD	GDSC	6.007	Gain
CMGC_GSK_GSK3B_ST	P30291	WEE1	P49841	GSK3B	S293	I286V	286	Missense	distal	-7	no	6.714	6.708	EPSD	GDSC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	P30291	WEE1	P49841	GSK3B	S293	N290S	290	Missense	distal	-3	no	6.714	6.809	EPSD	GDSC	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	P30291	WEE1	P49841	GSK3B	S293	Y295H	295	Missense	proximal	2	no	6.714	6.622	EPSD	GDSC;CCLE	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	P30291	WEE1	P49841	GSK3B	S480	N485S	485	Missense	distal	5	no	6.217	6.537	EPSD	GDSC	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	P30291	WEE1	P49841	GSK3B	S576	A577P	577	Missense	proximal	1	no	2.849	6.581	EPSD	GDSC;CCLE	6.007	Gain
CMGC_GSK_GSK3B_ST	Q14195	DPYSL3	P49841	GSK3B	S472	C471*	471	Missense	proximal	-1	no	7.743	7.570	EPSD	GDSC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	P54252	ATXN3	P49841	GSK3B	S256	R250H	250	Missense	distal	-6	no	7.524	7.547	PhosphoSitePlus	GDSC;CCLE	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	Q15910	EZH2	P49841	GSK3B	S76	T80P	80	Missense	distal	4	no	7.147	5.045	EPSD	GDSC;CCLE	6.007	Loss
CMGC_GSK_GSK3B_ST	Q9Y6H5	SNCAIP	P49841	GSK3B	S211	P206A	206	Missense	distal	-5	no	9.226	9.660	EPSD	GDSC	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	Q9Y6H5	SNCAIP	P49841	GSK3B	S211	V209I	209	Missense	proximal	-2	no	9.226	9.248	EPSD	GDSC;CCLE	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	Q9Y6H5	SNCAIP	P49841	GSK3B	T387	R381S	381	Missense	distal	-6	no	7.225	7.282	EPSD	GDSC;CCLE	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	Q02156	PRKCE	P49841	GSK3B	T228	D230V	230	Missense	proximal	2	no	6.783	6.421	EPSD	GDSC;CCLE	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	Q02156	PRKCE	P49841	GSK3B	S234	D230V	230	Missense	distal	-4	no	7.285	6.652	EPSD	GDSC;CCLE	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	Q02156	PRKCE	P49841	GSK3B	S329	P330L	330	Missense	proximal	1	no	7.855	4.995	EPSD	GDSC;CCLE	6.007	Loss
CMGC_GSK_GSK3B_ST	Q02156	PRKCE	P49841	GSK3B	S337	P330L	330	Missense	distal	-7	no	6.387	6.388	EPSD	GDSC;CCLE	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	Q02156	PRKCE	P49841	GSK3B	S381	R377Q	377	Missense	distal	-4	no	5.657	6.014	EPSD	GDSC	6.007	Gain
CMGC_GSK_GSK3B_ST	Q02156	PRKCE	P49841	GSK3B	T710	R704Q	704	Missense	distal	-6	no	6.249	6.301	EPSD	GDSC;CCLE	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	P10914	IRF1	P49841	GSK3B	S282	L289M	289	Missense	distal	7	no	6.331	6.714	EPSD	GDSC;CCLE	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	Q9BYG3	NIFK	P49841	GSK3B	T277	Q275K	275	Missense	proximal	-2	no	6.180	6.090	EPSD	GDSC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	Q9BYG3	NIFK	P49841	GSK3B	T279	Q275K	275	Missense	distal	-4	no	10.617	10.582	EPSD	GDSC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	P16220	CREB1	P49841	GSK3B	T104	S111L	111	Missense	distal	7	no	6.437	6.423	EPSD	GDSC;CCLE	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	P16220	CREB1	P49841	GSK3B	S117	S111L	111	Missense	distal	-6	no	8.249	8.248	EPSD	GDSC;CCLE	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	Q9H0Z9	RBM38	P49841	GSK3B	S195	Q189R	189	Missense	distal	-6	no	7.188	7.135	PhosphoSitePlus	GDSC;CCLE	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	Q01201	RELB	P49841	GSK3B	S37	S42L	42	Missense	distal	5	no	10.416	10.090	EPSD	GDSC;CCLE	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	Q01201	RELB	P49841	GSK3B	S44	S42L	42	Missense	proximal	-2	no	9.270	9.196	EPSD	GDSC;CCLE	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	Q01201	RELB	P49841	GSK3B	S573	S573F	573	Missense	central	0	yes	9.095	0.000	PhosphoSitePlus	GDSC;CCLE	6.007	Loss
CMGC_GSK_GSK3B_ST	Q04206	RELA	P49841	GSK3B	T71	Y66*	66	Missense	distal	-5	no	6.110	6.175	EPSD	GDSC	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	Q04206	RELA	P49841	GSK3B	T254	A258T	258	Missense	distal	4	no	5.659	7.201	EPSD	GDSC;CCLE	6.007	Gain
CMGC_GSK_GSK3B_ST	Q04206	RELA	P49841	GSK3B	T505	R509S	509	Missense	distal	4	no	6.176	9.214	EPSD	GDSC;CCLE	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	P30279	CCND2	P49841	GSK3B	T280	A278T	278	Missense	proximal	-2	no	9.037	9.399	PhosphoSitePlus	GDSC;CCLE	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	Q16555	DPYSL2	P49841	GSK3B	S522	Q526*	526	Missense	distal	4	no	7.344	10.296	EPSD	GDSC	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	Q16236	NFE2L2	P49841	GSK3B	S410	P409S	409	Missense	proximal	-1	no	6.994	6.938	EPSD	GDSC;CCLE	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	P12524	MYCL	P49841	GSK3B	S38	P40L	40	Missense	proximal	2	no	11.170	10.786	PhosphoSitePlus;EPSD	GDSC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	P12524	MYCL	P49841	GSK3B	S42	P40L	40	Missense	proximal	-2	no	8.597	8.267	EPSD;PhosphoSitePlus	GDSC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	Q14494	NFE2L1	P49841	GSK3B	S112	G115D	115	Missense	distal	3	no	7.059	7.110	EPSD	GDSC;CCLE	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	Q14494	NFE2L1	P49841	GSK3B	S116	G115D	115	Missense	proximal	-1	no	8.993	8.926	EPSD	GDSC;CCLE	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	Q14494	NFE2L1	P49841	GSK3B	S379	V382M	382	Missense	distal	3	no	7.123	7.140	PhosphoSitePlus	GDSC;CCLE	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	Q14494	NFE2L1	P49841	GSK3B	S500	S503F	503	Missense	distal	3	no	7.860	7.649	EPSD	GDSC;CCLE	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	Q14494	NFE2L1	P49841	GSK3B	S501	S503F	503	Missense	proximal	2	no	7.603	7.258	EPSD	GDSC;CCLE	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	Q14494	NFE2L1	P49841	GSK3B	S502	S503F	503	Missense	proximal	1	no	6.810	6.424	EPSD	GDSC;CCLE	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	Q14494	NFE2L1	P49841	GSK3B	S507	S503F	503	Missense	distal	-4	no	7.582	6.428	EPSD	GDSC;CCLE	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	Q14494	NFE2L1	P49841	GSK3B	S508	S503F	503	Missense	distal	-5	no	6.503	7.063	EPSD	GDSC;CCLE	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	Q14494	NFE2L1	P49841	GSK3B	S509	S503F	503	Missense	distal	-6	no	6.369	6.315	EPSD	GDSC;CCLE	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	Q7KZI7	MARK2	P49841	GSK3B	S26	L21S	21	Missense	distal	-5	no	6.609	6.500	EPSD	GDSC;CCLE	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	O00327	ARNTL	P49841	GSK3B	S512	S519R	519	Missense	distal	7	no	5.757	6.195	EPSD	GDSC	6.007	Gain
CMGC_GSK_GSK3B_ST	O00327	ARNTL	P49841	GSK3B	S515	S519R	519	Missense	distal	4	no	7.085	4.048	EPSD	GDSC	6.007	Loss
CMGC_GSK_GSK3B_ST	O00327	ARNTL	P49841	GSK3B	S516	S519R	519	Missense	distal	3	no	7.707	7.336	EPSD	GDSC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	O00327	ARNTL	P49841	GSK3B	S520	S519R	519	Missense	proximal	-1	no	6.514	6.377	EPSD	GDSC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	O00327	ARNTL	P49841	GSK3B	S592	S591N	591	Missense	proximal	-1	no	6.736	6.798	EPSD	GDSC	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	Q13887	KLF5	P49841	GSK3B	S441	N439T	439	Missense	proximal	-2	no	6.012	6.268	EPSD	GDSC;CCLE	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	Q13887	KLF5	P49841	GSK3B	S441	G436R	436	Missense	distal	-5	no	6.012	6.243	EPSD	GDSC;CCLE	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	Q13887	KLF5	P49841	GSK3B	S445	A449T	449	Missense	distal	4	no	7.376	8.919	EPSD	GDSC;CCLE	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	Q13887	KLF5	P49841	GSK3B	S445	N439T	439	Missense	distal	-6	no	7.376	7.320	EPSD	GDSC;CCLE	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	O15516	CLOCK	P49841	GSK3B	S8	S12P	12	Missense	distal	4	no	6.400	3.429	EPSD	GDSC	6.007	Loss
CMGC_GSK_GSK3B_ST	O15516	CLOCK	P49841	GSK3B	S394	E397K	397	Missense	distal	3	no	6.883	6.776	EPSD	GDSC;CCLE	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	O15516	CLOCK	P49841	GSK3B	S836	R831Q	831	Missense	distal	-5	no	6.348	5.794	EPSD	GDSC;CCLE	6.007	Loss
CMGC_GSK_GSK3B_ST	O15516	CLOCK	P49841	GSK3B	S836	P838L	838	Missense	proximal	2	no	6.348	5.964	EPSD	GDSC;CCLE	6.007	Loss
CMGC_GSK_GSK3B_ST	P30281	CCND3	P49841	GSK3B	S133	P134S	134	Missense	proximal	1	no	8.166	4.321	EPSD	GDSC	6.007	Loss
CMGC_GSK_GSK3B_ST	P53805	RCAN1	P49841	GSK3B	S163	S163C	163	Missense	central	0	yes	12.223	0.000	PhosphoSitePlus	GDSC;CCLE	6.007	Loss
CMGC_GSK_GSK3B_ST	P53805	RCAN1	P49841	GSK3B	S167	S163C	163	Missense	distal	-4	no	6.637	4.523	EPSD	GDSC;CCLE	6.007	Loss
CMGC_GSK_GSK3B_ST	P53805	RCAN1	P49841	GSK3B	T247	T241S	241	Missense	distal	-6	no	6.145	6.203	EPSD	GDSC;CCLE	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	P04198	MYCN	P49841	GSK3B	T58	L61P	61	Missense	distal	3	no	12.373	12.692	PhosphoSitePlus	GDSC;CCLE	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	P04198	MYCN	P49841	GSK3B	S369	R373*	373	Missense	distal	4	no	3.867	6.294	EPSD	GDSC	6.007	Gain
CMGC_GSK_GSK3B_ST	P04198	MYCN	P49841	GSK3B	S371	R373*	373	Missense	proximal	2	no	9.672	8.689	EPSD	GDSC	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	P54132	BLM	P49841	GSK3B	S131	A135T	135	Missense	distal	4	no	5.966	7.509	EPSD	GDSC;CCLE	6.007	Gain
CMGC_GSK_GSK3B_ST	P54132	BLM	P49841	GSK3B	S144	T150A	150	Missense	distal	6	no	7.561	7.557	EPSD	GDSC;CCLE	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	P54132	BLM	P49841	GSK3B	S304	E307G	307	Missense	distal	3	no	7.653	7.716	EPSD	GDSC;CCLE	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	P54132	BLM	P49841	GSK3B	S312	E307G	307	Missense	distal	-5	no	6.066	6.101	EPSD	GDSC;CCLE	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	P54132	BLM	P49841	GSK3B	S316	K323R	323	Missense	distal	7	no	6.978	7.485	EPSD	GDSC	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	P54132	BLM	P49841	GSK3B	S422	D420H	420	Missense	proximal	-2	no	6.516	6.426	EPSD	GDSC;CCLE	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	P54132	BLM	P49841	GSK3B	S456	H457R	457	Missense	proximal	1	no	5.998	7.379	EPSD	GDSC;CCLE	6.007	Gain
CMGC_GSK_GSK3B_ST	P54132	BLM	P49841	GSK3B	S601	A603V	603	Missense	proximal	2	no	6.085	5.808	EPSD	GDSC;CCLE	6.007	Loss
CMGC_GSK_GSK3B_ST	P54132	BLM	P49841	GSK3B	S714	V721A	721	Missense	distal	7	no	11.395	11.317	EPSD	GDSC;CCLE	6.007	Down-regulation
CAMK_MAPKAPK_MK2_MAPKAPK3_ST	Q8N5C8	TAB3	Q16644	MAPKAPK3	S103	H100Q	100	Missense	distal	-3	no	0.014	0.013	EPSD	GDSC;CCLE	0.011	Down-regulation
CAMK_MAPKAPK_MK2_MAPKAPK3_ST	Q8N5C8	TAB3	Q16644	MAPKAPK3	S411	S408N	408	Missense	distal	-3	no	0.013	0.015	EPSD	GDSC;CCLE	0.011	Up-regulation
CAMK_MAPKAPK_MK2_MAPKAPK3_ST	Q8N5C8	TAB3	Q16644	MAPKAPK3	S415	S408N	408	Missense	distal	-7	no	0.023	0.024	EPSD	GDSC;CCLE	0.011	Up-regulation
CAMK_MAPKAPK_MK2_MAPKAPK3_ST	Q8N5C8	TAB3	Q16644	MAPKAPK3	S563	R561S	561	Missense	proximal	-2	no	0.021	0.026	EPSD	GDSC;CCLE	0.011	Up-regulation
TK_Tec_BMX_Y	Q16611	BAK1	P51813	BMX	Y108	P102S	102	Missense	distal	-6	no	4.703	4.771	PhosphoSitePlus	GDSC;CCLE	2.549	Up-regulation
Other_PLK_PLK2_PLK2_ST	Q9HC77	CENPJ	Q9NYY3	PLK2	S131	K134I	134	Missense	distal	3	no	14.944	15.756	EPSD	GDSC;CCLE	13.807	Up-regulation
Other_PLK_PLK2_PLK2_ST	Q9HC77	CENPJ	Q9NYY3	PLK2	S683	S683A	683	Missense	central	0	yes	14.691	0.000	EPSD	GDSC;CCLE	13.807	Loss
Other_PLK_PLK2_PLK2_ST	Q9HC77	CENPJ	Q9NYY3	PLK2	S759	D766E	766	Missense	distal	7	no	16.334	16.273	EPSD	GDSC	13.807	Down-regulation
Other_PLK_PLK2_PLK2_ST	Q9HC77	CENPJ	Q9NYY3	PLK2	S1081	S1075F	1075	Missense	distal	-6	no	14.567	14.093	EPSD	GDSC;CCLE	13.807	Down-regulation
Other_PLK_PLK2_PLK2_ST	Q9HC77	CENPJ	Q9NYY3	PLK2	S1081	G1086*	1086	Missense	distal	5	no	14.567	14.482	EPSD	GDSC	13.807	Down-regulation
Other_PLK_PLK2_PLK2_ST	O43852	CALU	Q9NYY3	PLK2	S44	N40I	40	Missense	distal	-4	no	22.199	22.422	PhosphoSitePlus;EPSD	GDSC;CCLE	13.807	Up-regulation
Other_PLK_PLK2_PLK2_ST	P06748	NPM1	Q9NYY3	PLK2	S227	P220L	220	Missense	distal	-7	no	16.523	17.412	EPSD	GDSC;CCLE	13.807	Up-regulation
Other_PLK_PLK2_PLK2_ST	Q969H0	FBXW7	Q9NYY3	PLK2	S10	R13*	13	Missense	distal	3	no	13.508	14.864	EPSD	GDSC	13.807	Gain
Other_PLK_PLK2_PLK2_ST	Q16143	SNCB	Q9NYY3	PLK2	S118	E117K	117	Missense	proximal	-1	no	13.950	13.781	PhosphoSitePlus	GDSC;CCLE	13.807	Loss
Other_PLK_PLK2_PLK2_ST	P37840	SNCA	Q9NYY3	PLK2	S129	M127I	127	Missense	proximal	-2	no	17.753	18.968	PhosphoSitePlus	GDSC	13.807	Up-regulation
Other_PLK_PLK2_PLK2_ST	P37840	SNCA	Q9NYY3	PLK2	S129	E130G	130	Missense	proximal	1	no	17.753	19.432	PhosphoSitePlus	GDSC	13.807	Up-regulation
CMGC_DYRK_DYRK1_DYRK1B_ST	Q9Y463	DYRK1B	Q9Y463	DYRK1B	T41	A36P	36	Missense	distal	-5	no	0.066	0.062	EPSD	GDSC;CCLE	0.062	Down-regulation
CMGC_DYRK_DYRK1_DYRK1B_ST	O75533	SF3B1	Q9Y463	DYRK1B	S129	E131*	131	Missense	proximal	2	no	0.090	0.084	EPSD	GDSC	0.062	Down-regulation
CMGC_DYRK_DYRK1_DYRK1B_ST	O75533	SF3B1	Q9Y463	DYRK1B	T273	T273A	273	Missense	central	0	yes	0.063	0.000	EPSD	GDSC;CCLE	0.062	Loss
CAMK_MAPKAPK_MNK_MKNK2_ST	P23246	SFPQ	Q9HBH9	MKNK2	S283	E290D	290	Missense	distal	7	no	32.280	32.397	PhosphoSitePlus;EPSD	GDSC;CCLE	18.660	Up-regulation
CAMK_MAPKAPK_MNK_MKNK2_ST	O43597	SPRY2	Q9HBH9	MKNK2	S97	R104*	104	Missense	distal	7	no	18.667	18.193	EPSD	GDSC	18.660	Loss
CAMK_MAPKAPK_MNK_MKNK2_ST	Q15149	PLEC	Q9HBH9	MKNK2	S714	E710K	710	Missense	distal	-4	no	22.482	23.520	EPSD	GDSC;CCLE	18.660	Up-regulation
CAMK_MAPKAPK_MNK_MKNK2_ST	Q15149	PLEC	Q9HBH9	MKNK2	S720	A722S	722	Missense	proximal	2	no	18.985	18.774	EPSD	GDSC;CCLE	18.660	Down-regulation
CAMK_MAPKAPK_MNK_MKNK2_ST	Q15149	PLEC	Q9HBH9	MKNK2	S4271	E4264K	4264	Missense	distal	-7	no	20.075	18.898	EPSD	GDSC;CCLE	18.660	Down-regulation
CAMK_MAPKAPK_MNK_MKNK2_ST	Q15149	PLEC	Q9HBH9	MKNK2	S4386	Y4393S	4393	Missense	distal	7	no	20.257	20.595	EPSD	GDSC;CCLE	18.660	Up-regulation
CAMK_MAPKAPK_MNK_MKNK2_ST	Q15149	PLEC	Q9HBH9	MKNK2	S4392	Y4393S	4393	Missense	proximal	1	no	14.736	19.573	EPSD	GDSC;CCLE	18.660	Gain
CAMK_MAPKAPK_MNK_MKNK2_ST	Q15149	PLEC	Q9HBH9	MKNK2	S4396	Y4393S	4393	Missense	distal	-3	no	16.335	18.689	EPSD	GDSC;CCLE	18.660	Gain
CAMK_MAPKAPK_MNK_MKNK2_ST	Q15149	PLEC	Q9HBH9	MKNK2	S4616	V4617I	4617	Missense	proximal	1	no	21.918	23.690	EPSD	GDSC;CCLE	18.660	Up-regulation
CAMK_MAPKAPK_MNK_MKNK2_ST	Q15149	PLEC	Q9HBH9	MKNK2	S4616	S4618N	4618	Missense	proximal	2	no	21.918	21.943	EPSD	GDSC;CCLE	18.660	Up-regulation
CAMK_MAPKAPK_MNK_MKNK2_ST	Q15149	PLEC	Q9HBH9	MKNK2	T4628	S4626T	4626	Missense	proximal	-2	no	19.482	16.249	EPSD	GDSC	18.660	Loss
CAMK_MAPKAPK_MNK_MKNK2_ST	Q15149	PLEC	Q9HBH9	MKNK2	S4630	S4626T	4626	Missense	distal	-4	no	18.991	18.180	EPSD	GDSC	18.660	Loss
CAMK_PIM_PIM3_ST	Q92934	BAD	Q86V86	PIM3	S34	D29N	29	Missense	distal	-5	no	4.013	3.686	EPSD	GDSC	3.716	Loss
CAMK_PIM_PIM3_ST	Q92934	BAD	Q86V86	PIM3	S134	T137K	137	Missense	distal	3	no	4.190	4.772	EPSD	GDSC	3.716	Up-regulation
CAMK_PIM_PIM3_ST	Q92934	BAD	Q86V86	PIM3	S134	L129F	129	Missense	distal	-5	no	4.190	3.917	EPSD	GDSC	3.716	Down-regulation
CAMK_PIM_PIM3_ST	Q92934	BAD	Q86V86	PIM3	T137	T137K	137	Missense	central	0	yes	4.733	0.000	EPSD	GDSC	3.716	Loss
CAMK_PIM_PIM3_ST	Q92934	BAD	Q86V86	PIM3	S145	F151L	151	Missense	distal	6	no	4.030	3.885	EPSD	GDSC;CCLE	3.716	Down-regulation
CAMK_PIM_PIM3_ST	Q92934	BAD	Q86V86	PIM3	T148	F151L	151	Missense	distal	3	no	3.864	3.634	EPSD	GDSC;CCLE	3.716	Loss
CAMK_PIM_PIM3_ST	P35568	IRS1	Q86V86	PIM3	S270	R267C	267	Missense	distal	-3	no	4.559	2.055	EPSD	GDSC;CCLE	3.716	Loss
CAMK_PIM_PIM3_ST	P35568	IRS1	Q86V86	PIM3	S374	H371R	371	Missense	distal	-3	no	3.618	5.107	EPSD	GDSC	3.716	Gain
CAMK_PIM_PIM3_ST	P35568	IRS1	Q86V86	PIM3	S374	P376L	376	Missense	proximal	2	no	3.618	3.740	EPSD	GDSC;CCLE	3.716	Gain
CAMK_PIM_PIM3_ST	P35568	IRS1	Q86V86	PIM3	S415	R411*	411	Missense	distal	-4	no	4.182	5.432	EPSD	GDSC	3.716	Up-regulation
CAMK_PIM_PIM3_ST	P35568	IRS1	Q86V86	PIM3	S603	G597E	597	Missense	distal	-6	no	4.669	4.478	EPSD	GDSC	3.716	Down-regulation
CAMK_PIM_PIM3_ST	P35568	IRS1	Q86V86	PIM3	S636	A642S	642	Missense	distal	6	no	3.533	3.870	EPSD	GDSC;CCLE	3.716	Gain
CAMK_PIM_PIM3_ST	P35568	IRS1	Q86V86	PIM3	T859	R854C	854	Missense	distal	-5	no	4.638	3.183	EPSD	GDSC	3.716	Loss
CAMK_PIM_PIM3_ST	P35568	IRS1	Q86V86	PIM3	T870	L871F	871	Missense	proximal	1	no	4.657	4.754	EPSD	GDSC;CCLE	3.716	Up-regulation
CAMK_PIM_PIM3_ST	P35568	IRS1	Q86V86	PIM3	S1101	R1096G	1096	Missense	distal	-5	no	8.897	7.698	PhosphoSitePlus	GDSC;CCLE	3.716	Down-regulation
TK_Src_SrcB_LCK_Y	P06127	CD5	P06239	LCK	Y453	Y453*	453	Missense	central	0	yes	8.886	0.000	PhosphoSitePlus;EPSD	GDSC	5.050	Loss
TK_Src_SrcB_LCK_Y	P06127	CD5	P06239	LCK	Y453	Q455H	455	Missense	proximal	2	no	8.886	9.254	PhosphoSitePlus;EPSD	GDSC	5.050	Up-regulation
TK_Src_SrcB_LCK_Y	Q9H204	MED28	P06239	LCK	Y64	T68A	68	Missense	distal	4	no	6.252	6.635	PhosphoSitePlus	GDSC;CCLE	5.050	Up-regulation
TK_Src_SrcB_LCK_Y	P14784	IL2RB	P06239	LCK	Y418	G413W	413	Missense	distal	-5	no	6.809	5.712	PhosphoSitePlus;EPSD	GDSC;CCLE	5.050	Down-regulation
TK_Src_SrcB_LCK_Y	P29353	SHC1	P06239	LCK	Y349	Y349H	349	Missense	central	0	yes	8.905	0.000	EPSD	GDSC;CCLE	5.050	Loss
TK_Src_SrcB_LCK_Y	P29353	SHC1	P06239	LCK	Y350	Y349H	349	Missense	proximal	-1	no	7.492	8.094	EPSD	GDSC;CCLE	5.050	Up-regulation
TK_Src_SrcB_LCK_Y	P20963	CD247	P06239	LCK	Y123	G127E	127	Missense	distal	4	no	7.621	8.379	EPSD	GDSC;CCLE	5.050	Up-regulation
TK_Src_SrcB_LCK_Y	P20963	CD247	P06239	LCK	Y142	G140S	140	Missense	proximal	-2	no	8.002	8.084	PhosphoSitePlus	GDSC;CCLE	5.050	Up-regulation
TK_Src_SrcB_LCK_Y	P20963	CD247	P06239	LCK	Y153	Y153H	153	Missense	central	0	yes	7.641	0.000	EPSD	GDSC;CCLE	5.050	Loss
TK_Src_SrcB_LCK_Y	P20963	CD247	P06239	LCK	Y153	A155V	155	Missense	proximal	2	no	7.641	6.341	EPSD	GDSC;CCLE	5.050	Down-regulation
TK_Src_SrcB_LCK_Y	P43403	ZAP70	P06239	LCK	Y292	G291E	291	Missense	proximal	-1	no	6.681	8.535	EPSD;PhosphoSitePlus	GDSC;CCLE	5.050	Up-regulation
TK_Src_SrcB_LCK_Y	P43403	ZAP70	P06239	LCK	Y474	V470F	470	Missense	distal	-4	no	6.933	6.576	EPSD;PhosphoSitePlus	GDSC;CCLE	5.050	Down-regulation
TK_Src_SrcB_LCK_Y	P43403	ZAP70	P06239	LCK	Y492	Y492H	492	Missense	central	0	yes	8.350	0.000	EPSD;PhosphoSitePlus	GDSC;CCLE	5.050	Loss
TK_Src_SrcB_LCK_Y	P43403	ZAP70	P06239	LCK	Y493	Y492H	492	Missense	proximal	-1	no	6.652	7.253	EPSD;PhosphoSitePlus	GDSC;CCLE	5.050	Up-regulation
TK_Src_SrcB_LCK_Y	P43403	ZAP70	P06239	LCK	Y569	C575F	575	Missense	distal	6	no	7.233	6.419	EPSD	GDSC;CCLE	5.050	Down-regulation
TK_Src_SrcB_LCK_Y	Q8IWV1	LAX1	P06239	LCK	Y373	E374D	374	Missense	proximal	1	no	7.808	7.903	EPSD;PhosphoSitePlus	GDSC;CCLE	5.050	Up-regulation
TK_Src_SrcB_LCK_Y	P29350	PTPN6	P06239	LCK	Y509	Y509*	509	Missense	central	0	yes	5.697	0.000	EPSD	GDSC	5.050	Loss
TK_Src_SrcB_LCK_Y	P29350	PTPN6	P06239	LCK	Y536	S534L	534	Missense	proximal	-2	no	6.084	5.002	EPSD;PhosphoSitePlus	GDSC	5.050	Loss
TK_Src_SrcB_LCK_Y	Q13094	LCP2	P06239	LCK	Y113	S107Y	107	Missense	distal	-6	no	8.611	8.402	EPSD;PhosphoSitePlus	GDSC;CCLE	5.050	Down-regulation
TK_Src_SrcB_LCK_Y	Q13094	LCP2	P06239	LCK	Y128	G126E	126	Missense	proximal	-2	no	9.064	9.747	EPSD;PhosphoSitePlus	GDSC	5.050	Up-regulation
TK_Src_SrcB_LCK_Y	Q13094	LCP2	P06239	LCK	Y483	Y476F	476	Missense	distal	-7	no	6.119	6.018	EPSD	GDSC;CCLE	5.050	Down-regulation
TK_Src_SrcB_LCK_Y	P42229	STAT5A	P06239	LCK	Y171	E178*	178	Missense	distal	7	no	6.645	6.185	EPSD	GDSC	5.050	Down-regulation
TK_Src_SrcB_LCK_Y	P42229	STAT5A	P06239	LCK	Y694	P697L	697	Missense	distal	3	no	5.862	6.577	PhosphoSitePlus	GDSC	5.050	Up-regulation
TK_Src_SrcB_LCK_Y	Q13291	SLAMF1	P06239	LCK	Y269	T266M	266	Missense	distal	-3	no	5.449	4.566	EPSD	GDSC;CCLE	5.050	Loss
TK_Src_SrcB_LCK_Y	Q13291	SLAMF1	P06239	LCK	Y281	P287T	287	Missense	distal	6	no	5.141	5.038	EPSD	GDSC;CCLE	5.050	Loss
TK_Src_SrcB_LCK_Y	Q13291	SLAMF1	P06239	LCK	Y327	A328V	328	Missense	proximal	1	no	7.182	7.071	EPSD	GDSC;CCLE	5.050	Down-regulation
TK_Src_SrcB_LCK_Y	Q13291	SLAMF1	P06239	LCK	Y327	Y327C	327	Missense	central	0	yes	7.182	0.000	EPSD	GDSC;CCLE	5.050	Loss
TK_Src_SrcB_LCK_Y	Q13291	SLAMF1	P06239	LCK	Y327	E334D	334	Missense	distal	7	no	7.182	7.136	EPSD	GDSC;CCLE	5.050	Down-regulation
TK_Src_SrcB_LCK_Y	Q13444	ADAM15	P06239	LCK	Y735	P742L	742	Missense	distal	7	no	6.300	6.198	EPSD	GDSC;CCLE	5.050	Down-regulation
TK_Src_SrcB_LCK_Y	P22681	CBL	P06239	LCK	Y455	N454K	454	Missense	proximal	-1	no	5.839	5.530	EPSD	GDSC;CCLE	5.050	Down-regulation
TK_Src_SrcB_LCK_Y	P22681	CBL	P06239	LCK	Y674	N671S	671	Missense	distal	-3	no	8.284	7.331	EPSD	GDSC;CCLE	5.050	Down-regulation
TK_Src_SrcB_LCK_Y	P22681	CBL	P06239	LCK	Y700	Y700C	700	Missense	central	0	yes	8.996	0.000	PhosphoSitePlus;EPSD	GDSC;CCLE	5.050	Loss
TK_Src_SrcB_LCK_Y	P22681	CBL	P06239	LCK	Y731	Q738*	738	Missense	distal	7	no	8.083	7.624	EPSD;PhosphoSitePlus	GDSC	5.050	Down-regulation
TK_Src_SrcB_LCK_Y	P22681	CBL	P06239	LCK	Y774	D772E	772	Missense	proximal	-2	no	8.964	8.715	EPSD;PhosphoSitePlus	GDSC	5.050	Down-regulation
TK_Src_SrcB_LCK_Y	P60484	PTEN	P06239	LCK	Y155	Q149*	149	Missense	distal	-6	no	5.347	3.797	EPSD	GDSC	5.050	Loss
TK_Src_SrcB_LCK_Y	P60484	PTEN	P06239	LCK	Y155	A151P	151	Missense	distal	-4	no	5.347	5.508	EPSD	GDSC;CCLE	5.050	Up-regulation
TK_Src_SrcB_LCK_Y	P60484	PTEN	P06239	LCK	Y176	Y177*	177	Missense	proximal	1	no	5.532	3.995	EPSD	GDSC	5.050	Loss
TK_Src_SrcB_LCK_Y	P60484	PTEN	P06239	LCK	Y240	R233*	233	Missense	distal	-7	no	6.412	5.469	EPSD;PhosphoSitePlus	GDSC	5.050	Down-regulation
TK_Src_SrcB_LCK_Y	Q04759	PRKCQ	P06239	LCK	Y90	A93D	93	Missense	distal	3	no	7.972	6.510	PhosphoSitePlus	GDSC;CCLE	5.050	Down-regulation
TK_Src_SrcB_LCK_Y	P23743	DGKA	P06239	LCK	Y669	L672F	672	Missense	distal	3	no	5.148	4.869	EPSD	GDSC;CCLE	5.050	Loss
TK_Src_SrcB_LCK_Y	Q96LC7	SIGLEC10	P06239	LCK	Y597	I594M	594	Missense	distal	-3	no	6.695	6.531	EPSD;PhosphoSitePlus	GDSC;CCLE	5.050	Down-regulation
TK_Src_SrcB_LCK_Y	Q96LC7	SIGLEC10	P06239	LCK	Y667	L670F	670	Missense	distal	3	no	7.899	7.621	PhosphoSitePlus;EPSD	GDSC;CCLE	5.050	Down-regulation
TK_Src_SrcB_LCK_Y	Q96LC7	SIGLEC10	P06239	LCK	Y667	H666D	666	Missense	proximal	-1	no	7.899	8.797	PhosphoSitePlus;EPSD	GDSC	5.050	Up-regulation
TK_Src_SrcB_LCK_Y	Q13283	G3BP1	P06239	LCK	Y174	S180T	180	Missense	distal	6	no	6.195	6.530	EPSD	GDSC	5.050	Up-regulation
TK_Src_SrcB_LCK_Y	Q08881	ITK	P06239	LCK	Y180	V176A	176	Missense	distal	-4	no	6.469	6.585	EPSD	GDSC;CCLE	5.050	Up-regulation
TK_Src_SrcB_LCK_Y	Q08881	ITK	P06239	LCK	Y512	T518I	518	Missense	distal	6	no	7.871	8.030	PhosphoSitePlus	GDSC;CCLE	5.050	Up-regulation
TK_Src_SrcB_LCK_Y	Q08881	ITK	P06239	LCK	Y512	Q511*	511	Missense	proximal	-1	no	7.871	6.404	PhosphoSitePlus	GDSC	5.050	Down-regulation
TK_Src_SrcB_LCK_Y	Q08881	ITK	P06239	LCK	Y512	L508M	508	Missense	distal	-4	no	7.871	8.670	PhosphoSitePlus	GDSC;CCLE	5.050	Up-regulation
TK_Src_SrcB_LCK_Y	P15311	EZR	P06239	LCK	Y291	R293H	293	Missense	proximal	2	no	4.761	5.312	EPSD	GDSC;CCLE	5.050	Gain
TK_Src_SrcB_LCK_Y	P15311	EZR	P06239	LCK	Y478	P476S	476	Missense	proximal	-2	no	6.042	6.136	EPSD	GDSC;CCLE	5.050	Up-regulation
TK_Src_SrcB_LCK_Y	Q9UHD2	TBK1	P06239	LCK	Y185	Y185C	185	Missense	central	0	yes	5.617	0.000	EPSD	GDSC;CCLE	5.050	Loss
TK_Src_SrcB_LCK_Y	Q9UHD2	TBK1	P06239	LCK	Y185	P182L	182	Missense	distal	-3	no	5.617	5.383	EPSD	GDSC;CCLE	5.050	Down-regulation
TK_Src_SrcB_LCK_Y	Q9UHD2	TBK1	P06239	LCK	Y325	H322Y	322	Missense	distal	-3	no	3.779	5.095	EPSD	GDSC	5.050	Gain
TK_Src_SrcB_LCK_Y	Q9UHD2	TBK1	P06239	LCK	Y354	R357*	357	Missense	distal	3	no	6.710	5.750	PhosphoSitePlus;EPSD	GDSC	5.050	Down-regulation
TK_Src_SrcB_LCK_Y	Q9UHD2	TBK1	P06239	LCK	Y354	R358C	358	Missense	distal	4	no	6.710	5.367	PhosphoSitePlus;EPSD	GDSC;CCLE	5.050	Down-regulation
TK_Src_SrcB_LCK_Y	Q9BZS1	FOXP3	P06239	LCK	Y342	R337*	337	Missense	distal	-5	no	6.412	5.188	PhosphoSitePlus	GDSC	5.050	Down-regulation
Other_KIS_UHMK1_ST	Q15637	SF1	Q8TAS1	UHMK1	T232	Q228*	228	Missense	distal	-4	no	1.899	1.886	EPSD	GDSC	1.522	Down-regulation
Other_KIS_UHMK1_ST	Q9BSJ6	PIMREG	Q8TAS1	UHMK1	S247	D243N	243	Missense	distal	-4	no	2.195	2.209	EPSD	GDSC	1.522	Up-regulation
Other_KIS_UHMK1_ST	P46527	CDKN1B	Q8TAS1	UHMK1	S112	I119V	119	Missense	distal	7	no	1.641	1.613	EPSD	GDSC;CCLE	1.522	Down-regulation
Other_KIS_UHMK1_ST	P46527	CDKN1B	Q8TAS1	UHMK1	S178	G177S	177	Missense	proximal	-1	no	1.784	1.487	EPSD	GDSC;CCLE	1.522	Loss
Other_KIS_UHMK1_ST	P16949	STMN1	Q8TAS1	UHMK1	S38	P36T	36	Missense	proximal	-2	no	4.392	4.218	PhosphoSitePlus	GDSC;CCLE	1.522	Down-regulation
Other_IKK_IKBKE_ST	Q96FA3	PELI1	Q14164	IKBKE	T80	T86N	86	Missense	distal	6	no	95.218	86.255	PhosphoSitePlus;EPSD	GDSC;CCLE	71.554	Down-regulation
Other_IKK_IKBKE_ST	Q96FA3	PELI1	Q14164	IKBKE	S125	D126A	126	Missense	proximal	1	no	73.691	69.397	EPSD	GDSC;CCLE	71.554	Loss
Other_IKK_IKBKE_ST	Q96FA3	PELI1	Q14164	IKBKE	S129	D126A	126	Missense	distal	-3	no	79.238	74.899	EPSD	GDSC;CCLE	71.554	Down-regulation
Other_IKK_IKBKE_ST	Q96FA3	PELI1	Q14164	IKBKE	T288	P292S	292	Missense	distal	4	no	97.303	105.134	EPSD;PhosphoSitePlus	GDSC;CCLE	71.554	Up-regulation
Other_IKK_IKBKE_ST	Q96FA3	PELI1	Q14164	IKBKE	S293	P292S	292	Missense	proximal	-1	no	100.743	100.145	EPSD;PhosphoSitePlus	GDSC;CCLE	71.554	Down-regulation
Other_IKK_IKBKE_ST	O95644	NFATC1	Q14164	IKBKE	S269	P275L	275	Missense	distal	6	no	82.411	79.344	EPSD	GDSC	71.554	Down-regulation
Other_IKK_IKBKE_ST	Q14653	IRF3	Q14164	IKBKE	S386	T390A	390	Missense	distal	4	no	95.767	93.015	PhosphoSitePlus;EPSD	GDSC;CCLE	71.554	Down-regulation
Other_IKK_IKBKE_ST	Q14653	IRF3	Q14164	IKBKE	S386	R380Q	380	Missense	distal	-6	no	95.767	97.009	PhosphoSitePlus;EPSD	GDSC;CCLE	71.554	Up-regulation
Other_IKK_IKBKE_ST	Q14653	IRF3	Q14164	IKBKE	S396	T390A	390	Missense	distal	-6	no	94.340	95.766	EPSD;PhosphoSitePlus	GDSC;CCLE	71.554	Up-regulation
Other_IKK_IKBKE_ST	O95786	DDX58	Q14164	IKBKE	S855	E857G	857	Missense	proximal	2	no	99.185	97.483	PhosphoSitePlus	GDSC;CCLE	71.554	Down-regulation
Other_IKK_IKBKE_ST	P03372	ESR1	Q14164	IKBKE	T7	M1I	1	Missense	distal	-6	no	70.825	75.113	EPSD	GDSC	71.554	Gain
Other_IKK_IKBKE_ST	P03372	ESR1	Q14164	IKBKE	S167	G160S	160	Missense	distal	-7	no	96.639	96.162	PhosphoSitePlus	GDSC	71.554	Down-regulation
Other_IKK_IKBKE_ST	P03372	ESR1	Q14164	IKBKE	S167	R164I	164	Missense	distal	-3	no	96.639	93.464	PhosphoSitePlus	GDSC;CCLE	71.554	Down-regulation
Other_IKK_IKBKE_ST	P03372	ESR1	Q14164	IKBKE	S305	K299N	299	Missense	distal	-6	no	71.296	72.096	EPSD	GDSC;CCLE	71.554	Gain
Other_IKK_IKBKE_ST	P31749	AKT1	Q14164	IKBKE	T308	K307N	307	Missense	proximal	-1	no	94.602	97.492	EPSD;PhosphoSitePlus	GDSC;CCLE	71.554	Up-regulation
Other_IKK_IKBKE_ST	P31749	AKT1	Q14164	IKBKE	S473	G478S	478	Missense	distal	5	no	82.406	82.985	PhosphoSitePlus;EPSD	GDSC;CCLE	71.554	Up-regulation
Other_IKK_IKBKE_ST	P46937	YAP1	Q14164	IKBKE	S103	P98L	98	Missense	distal	-5	no	77.490	69.810	EPSD	GDSC;CCLE	71.554	Loss
Other_IKK_IKBKE_ST	P46937	YAP1	Q14164	IKBKE	S164	R161*	161	Missense	distal	-3	no	81.450	75.949	EPSD	GDSC	71.554	Down-regulation
Other_IKK_IKBKE_ST	P46937	YAP1	Q14164	IKBKE	S350	A347S	347	Missense	distal	-3	no	76.931	79.139	EPSD	GDSC	71.554	Up-regulation
Other_IKK_IKBKE_ST	P46937	YAP1	Q14164	IKBKE	S350	Q357P	357	Missense	distal	7	no	76.931	77.425	EPSD	GDSC	71.554	Up-regulation
Other_IKK_IKBKE_ST	P46937	YAP1	Q14164	IKBKE	S350	E356D	356	Missense	distal	6	no	76.931	79.270	EPSD	GDSC;CCLE	71.554	Up-regulation
Other_IKK_IKBKE_ST	O00571	DDX3X	Q14164	IKBKE	S183	I179N	179	Missense	distal	-4	no	70.188	76.581	EPSD	GDSC;CCLE	71.554	Gain
Other_IKK_IKBKE_ST	O00571	DDX3X	Q14164	IKBKE	S520	H527Q	527	Missense	distal	7	no	83.612	82.284	EPSD	GDSC;CCLE	71.554	Down-regulation
Other_IKK_IKBKE_ST	Q04206	RELA	Q14164	IKBKE	T254	D259G	259	Missense	distal	5	no	76.906	76.198	EPSD	GDSC;CCLE	71.554	Down-regulation
Other_IKK_IKBKE_ST	Q04206	RELA	Q14164	IKBKE	T254	A258T	258	Missense	distal	4	no	76.906	79.658	EPSD	GDSC;CCLE	71.554	Up-regulation
Other_IKK_IKBKE_ST	Q14164	IKBKE	Q14164	IKBKE	S172	E178D	178	Missense	distal	6	no	100.814	103.153	EPSD	GDSC;CCLE	71.554	Up-regulation
Other_IKK_IKBKE_ST	Q14164	IKBKE	Q14164	IKBKE	T474	A481T	481	Missense	distal	7	no	75.814	74.930	EPSD	GDSC	71.554	Down-regulation
Other_IKK_IKBKE_ST	Q14164	IKBKE	Q14164	IKBKE	S479	A481T	481	Missense	proximal	2	no	90.469	94.404	EPSD	GDSC	71.554	Up-regulation
Other_IKK_IKBKE_ST	O43524	FOXO3	Q14164	IKBKE	T313	V320I	320	Missense	distal	7	no	78.900	80.655	EPSD	GDSC;CCLE	71.554	Up-regulation
Other_IKK_IKBKE_ST	O43524	FOXO3	Q14164	IKBKE	S574	V576A	576	Missense	proximal	2	no	81.169	76.651	EPSD	GDSC;CCLE	71.554	Down-regulation
Other_IKK_IKBKE_ST	O43524	FOXO3	Q14164	IKBKE	S644	D643H	643	Missense	proximal	-1	no	92.654	88.758	PhosphoSitePlus	GDSC	71.554	Down-regulation
Other_IKK_IKBKE_ST	Q9UNN5	FAF1	Q14164	IKBKE	S314	V309I	309	Missense	distal	-5	no	77.414	77.334	EPSD	GDSC;CCLE	71.554	Down-regulation
CMGC_MAPK_p38_MAPK12_ST	P15172	MYOD1	P53778	MAPK12	S201	A199V	199	Missense	proximal	-2	no	132.509	128.540	PhosphoSitePlus;EPSD	GDSC;CCLE	112.929	Down-regulation
CMGC_MAPK_p38_MAPK12_ST	P15172	MYOD1	P53778	MAPK12	S201	P202L	202	Missense	proximal	1	no	132.509	115.764	PhosphoSitePlus;EPSD	GDSC;CCLE	112.929	Down-regulation
CMGC_MAPK_p38_MAPK12_ST	Q12959	DLG1	P53778	MAPK12	S206	V202D	202	Missense	distal	-4	no	107.821	120.858	EPSD	GDSC;CCLE	112.929	Gain
CMGC_MAPK_p38_MAPK12_ST	Q12959	DLG1	P53778	MAPK12	T209	V202D	202	Missense	distal	-7	no	136.800	134.225	EPSD;PhosphoSitePlus	GDSC;CCLE	112.929	Down-regulation
CMGC_MAPK_p38_MAPK12_ST	Q12959	DLG1	P53778	MAPK12	T209	L207S	207	Missense	proximal	-2	no	136.800	139.507	EPSD;PhosphoSitePlus	GDSC;CCLE	112.929	Up-regulation
CMGC_MAPK_p38_MAPK12_ST	Q12959	DLG1	P53778	MAPK12	S424	Q425L	425	Missense	proximal	1	no	-62.148	119.114	EPSD	GDSC;CCLE	112.929	Gain
CMGC_MAPK_p38_MAPK12_ST	Q12959	DLG1	P53778	MAPK12	S432	Q425L	425	Missense	distal	-7	no	137.071	137.791	EPSD	GDSC;CCLE	112.929	Up-regulation
CMGC_MAPK_p38_MAPK12_ST	Q12959	DLG1	P53778	MAPK12	S432	V427F	427	Missense	distal	-5	no	137.071	136.947	EPSD	GDSC	112.929	Down-regulation
CMGC_MAPK_p38_MAPK12_ST	Q00613	HSF1	P53778	MAPK12	S292	R296H	296	Missense	distal	4	no	125.557	125.678	EPSD	GDSC;CCLE	112.929	Up-regulation
CMGC_MAPK_p38_MAPK12_ST	Q00613	HSF1	P53778	MAPK12	S303	P308L	308	Missense	distal	5	no	135.892	135.196	EPSD;PhosphoSitePlus	GDSC	112.929	Down-regulation
CMGC_MAPK_p38_MAPK12_ST	Q00613	HSF1	P53778	MAPK12	S303	R296H	296	Missense	distal	-7	no	135.892	135.530	EPSD;PhosphoSitePlus	GDSC;CCLE	112.929	Down-regulation
CMGC_MAPK_p38_MAPK12_ST	Q00613	HSF1	P53778	MAPK12	S307	P308L	308	Missense	proximal	1	no	139.350	122.605	PhosphoSitePlus;EPSD	GDSC	112.929	Down-regulation
CMGC_MAPK_p38_MAPK12_ST	Q00613	HSF1	P53778	MAPK12	S307	E312A	312	Missense	distal	5	no	139.350	140.375	PhosphoSitePlus;EPSD	GDSC	112.929	Up-regulation
CMGC_MAPK_p38_MAPK12_ST	Q00613	HSF1	P53778	MAPK12	S314	P308L	308	Missense	distal	-6	no	116.105	119.128	EPSD	GDSC	112.929	Up-regulation
CMGC_MAPK_p38_MAPK12_ST	Q00613	HSF1	P53778	MAPK12	S314	E312A	312	Missense	proximal	-2	no	116.105	125.414	EPSD	GDSC	112.929	Up-regulation
CMGC_MAPK_p38_MAPK12_ST	Q00613	HSF1	P53778	MAPK12	S363	R360Q	360	Missense	distal	-3	no	129.909	129.923	EPSD	GDSC	112.929	Up-regulation
CMGC_MAPK_p38_MAPK12_ST	Q00613	HSF1	P53778	MAPK12	S363	R360W	360	Missense	distal	-3	no	129.909	129.987	EPSD	GDSC;CCLE	112.929	Up-regulation
CMGC_MAPK_p38_MAPK12_ST	Q00613	HSF1	P53778	MAPK12	S419	S419R	419	Missense	central	0	yes	129.769	0.000	EPSD	GDSC	112.929	Loss
CMGC_MAPK_p38_MAPK12_ST	Q00613	HSF1	P53778	MAPK12	S419	S421W	421	Missense	proximal	2	no	129.769	129.039	EPSD	GDSC	112.929	Down-regulation
CMGC_MAPK_p38_MAPK12_ST	Q00613	HSF1	P53778	MAPK12	S419	V422L	422	Missense	distal	3	no	129.769	129.819	EPSD	GDSC;CCLE	112.929	Up-regulation
CMGC_MAPK_p38_MAPK12_ST	Q00613	HSF1	P53778	MAPK12	S458	S458I	458	Missense	central	0	yes	120.860	0.000	EPSD	GDSC;CCLE	112.929	Loss
CMGC_MAPK_p38_MAPK12_ST	Q00613	HSF1	P53778	MAPK12	S461	S458I	458	Missense	distal	-3	no	125.143	125.078	EPSD	GDSC;CCLE	112.929	Down-regulation
CMGC_MAPK_p38_MAPK12_ST	P10636	MAPT	P53778	MAPK12	S46	A41V	41	Missense	distal	-5	no	119.116	118.865	EPSD	GDSC;CCLE	112.929	Down-regulation
CMGC_MAPK_p38_MAPK12_ST	P10636	MAPT	P53778	MAPK12	T50	Q49H	49	Missense	proximal	-1	no	134.448	134.742	EPSD	GDSC	112.929	Up-regulation
CMGC_MAPK_p38_MAPK12_ST	P10636	MAPT	P53778	MAPK12	S228	R222H	222	Missense	distal	-6	no	119.197	118.440	EPSD	GDSC;CCLE	112.929	Down-regulation
CMGC_MAPK_p38_MAPK12_ST	P10636	MAPT	P53778	MAPK12	T470	A475V	475	Missense	distal	5	no	129.712	128.909	EPSD	GDSC;CCLE	112.929	Down-regulation
CMGC_MAPK_p38_MAPK12_ST	P10636	MAPT	P53778	MAPK12	S739	S739C	739	Missense	central	0	yes	131.198	0.000	EPSD	GDSC	112.929	Loss
CMGC_MAPK_p38_MAPK12_ST	P10636	MAPT	P53778	MAPK12	T744	S739C	739	Missense	distal	-5	no	114.728	114.360	EPSD	GDSC	112.929	Down-regulation
CMGC_MAPK_p38_MAPK12_ST	P30281	CCND3	P53778	MAPK12	S133	P134S	134	Missense	proximal	1	no	123.799	53.314	EPSD	GDSC	112.929	Loss
STE_STE7_MEK4_MAP2K4_ST	P45985	MAP2K4	P45985	MAP2K4	S80	S80I	80	Missense	central	0	yes	0.006	0.000	EPSD	GDSC;CCLE	0.006	Loss
STE_STE7_MEK4_MAP2K4_ST	P45985	MAP2K4	P45985	MAP2K4	T391	I384T	384	Missense	distal	-7	no	0.008	0.009	EPSD	GDSC;CCLE	0.006	Up-regulation
STE_STE7_MEK4_MAP2K4_ST	P45985	MAP2K4	P45985	MAP2K4	T391	I384S	384	Missense	distal	-7	no	0.008	0.009	EPSD	GDSC;CCLE	0.006	Up-regulation
AGC_PDK1_PDPK1_ST	Q9HBY8	SGK2	O15530	PDPK1	S64	P65L	65	Missense	proximal	1	no	6.464	4.045	EPSD	GDSC;CCLE	3.516	Down-regulation
AGC_PDK1_PDPK1_ST	Q9HBY8	SGK2	O15530	PDPK1	S70	P65L	65	Missense	distal	-5	no	4.284	4.540	EPSD	GDSC;CCLE	3.516	Up-regulation
AGC_PDK1_PDPK1_ST	O15530	PDPK1	O15530	PDPK1	S92	S94P	94	Missense	proximal	2	no	5.413	5.366	EPSD	GDSC	3.516	Down-regulation
AGC_PDK1_PDPK1_ST	O15530	PDPK1	O15530	PDPK1	S396	G403D	403	Missense	distal	7	no	5.565	5.645	EPSD;PhosphoSitePlus	GDSC;CCLE	3.516	Up-regulation
AGC_PDK1_PDPK1_ST	O15530	PDPK1	O15530	PDPK1	S396	T402A	402	Missense	distal	6	no	5.565	5.566	EPSD;PhosphoSitePlus	GDSC;CCLE	3.516	Up-regulation
AGC_PDK1_PDPK1_ST	O15530	PDPK1	O15530	PDPK1	S410	G403D	403	Missense	distal	-7	no	4.858	4.291	EPSD;PhosphoSitePlus	GDSC;CCLE	3.516	Down-regulation
AGC_PDK1_PDPK1_ST	O15530	PDPK1	O15530	PDPK1	T513	H517Q	517	Missense	distal	4	no	5.407	5.213	EPSD;PhosphoSitePlus	GDSC;CCLE	3.516	Down-regulation
AGC_PDK1_PDPK1_ST	Q99814	EPAS1	O15530	PDPK1	S210	Y214C	214	Missense	distal	4	no	4.585	4.329	EPSD	GDSC;CCLE	3.516	Down-regulation
AGC_PDK1_PDPK1_ST	Q99814	EPAS1	O15530	PDPK1	S210	Y214*	214	Missense	distal	4	no	4.585	4.294	EPSD	GDSC	3.516	Down-regulation
AGC_PDK1_PDPK1_ST	Q99814	EPAS1	O15530	PDPK1	S672	P673S	673	Missense	proximal	1	no	7.070	4.275	EPSD	GDSC;CCLE	3.516	Down-regulation
AGC_PDK1_PDPK1_ST	Q99814	EPAS1	O15530	PDPK1	S677	P673S	673	Missense	distal	-4	no	4.508	4.551	EPSD	GDSC;CCLE	3.516	Up-regulation
AGC_PDK1_PDPK1_ST	Q99814	EPAS1	O15530	PDPK1	T678	P673S	673	Missense	distal	-5	no	4.790	4.761	EPSD	GDSC;CCLE	3.516	Down-regulation
AGC_PDK1_PDPK1_ST	Q99814	EPAS1	O15530	PDPK1	S696	A698P	698	Missense	proximal	2	no	3.601	3.605	EPSD	GDSC;CCLE	3.516	Up-regulation
AGC_PDK1_PDPK1_ST	Q99814	EPAS1	O15530	PDPK1	S696	S703T	703	Missense	distal	7	no	3.601	3.558	EPSD	GDSC;CCLE	3.516	Down-regulation
AGC_PDK1_PDPK1_ST	Q99814	EPAS1	O15530	PDPK1	S696	P697L	697	Missense	proximal	1	no	3.601	1.182	EPSD	GDSC;CCLE	3.516	Loss
AGC_PDK1_PDPK1_ST	P08559	PDHA1	O15530	PDPK1	S152	M155I	155	Missense	distal	3	no	3.613	3.242	EPSD	GDSC;CCLE	3.516	Loss
AGC_PDK1_PDPK1_ST	P08559	PDHA1	O15530	PDPK1	T286	Q285R	285	Missense	proximal	-1	no	4.364	4.382	EPSD	GDSC;CCLE	3.516	Up-regulation
AGC_PDK1_PDPK1_ST	P31751	AKT2	O15530	PDPK1	S126	S130Y	130	Missense	distal	4	no	6.928	6.063	EPSD	GDSC;CCLE	3.516	Down-regulation
AGC_PDK1_PDPK1_ST	P31751	AKT2	O15530	PDPK1	S126	S130A	130	Missense	distal	4	no	6.928	6.503	EPSD	GDSC;CCLE	3.516	Down-regulation
AGC_PDK1_PDPK1_ST	P05106	ITGB3	O15530	PDPK1	S619	C614R	614	Missense	distal	-5	no	4.333	4.207	EPSD	GDSC;CCLE	3.516	Down-regulation
AGC_PDK1_PDPK1_ST	P05106	ITGB3	O15530	PDPK1	S619	S619F	619	Missense	central	0	yes	4.333	0.000	EPSD	GDSC;CCLE	3.516	Loss
AGC_PDK1_PDPK1_ST	P05106	ITGB3	O15530	PDPK1	T779	A776D	776	Missense	distal	-3	no	4.971	4.629	PhosphoSitePlus	GDSC;CCLE	3.516	Down-regulation
AGC_PDK1_PDPK1_ST	P17612	PRKACA	O15530	PDPK1	S54	T52M	52	Missense	proximal	-2	no	6.069	6.007	EPSD	GDSC;CCLE	3.516	Down-regulation
AGC_PDK1_PDPK1_ST	P17612	PRKACA	O15530	PDPK1	S110	N114S	114	Missense	distal	4	no	3.366	3.971	EPSD	GDSC	3.516	Gain
AGC_PDK1_PDPK1_ST	P17612	PRKACA	O15530	PDPK1	T198	V192A	192	Missense	distal	-6	no	5.939	5.904	PhosphoSitePlus	GDSC;CCLE	3.516	Down-regulation
AGC_PDK1_PDPK1_ST	P31749	AKT1	O15530	PDPK1	T72	I75M	75	Missense	distal	3	no	5.536	5.908	EPSD	GDSC;CCLE	3.516	Up-regulation
AGC_PDK1_PDPK1_ST	P31749	AKT1	O15530	PDPK1	T308	K307N	307	Missense	proximal	-1	no	10.175	10.264	EPSD;PhosphoSitePlus	GDSC;CCLE	3.516	Up-regulation
AGC_PDK1_PDPK1_ST	P31749	AKT1	O15530	PDPK1	S473	G478S	478	Missense	distal	5	no	5.258	5.477	PhosphoSitePlus;EPSD	GDSC;CCLE	3.516	Up-regulation
AGC_PDK1_PDPK1_ST	O60331	PIP5K1C	O15530	PDPK1	S515	A519S	519	Missense	distal	4	no	6.523	6.948	EPSD	GDSC;CCLE	3.516	Up-regulation
AGC_PDK1_PDPK1_ST	O60331	PIP5K1C	O15530	PDPK1	T526	A519S	519	Missense	distal	-7	no	4.696	5.074	EPSD	GDSC;CCLE	3.516	Up-regulation
AGC_PDK1_PDPK1_ST	O60331	PIP5K1C	O15530	PDPK1	S539	T543M	543	Missense	distal	4	no	6.158	5.594	EPSD	GDSC	3.516	Down-regulation
AGC_PDK1_PDPK1_ST	O60331	PIP5K1C	O15530	PDPK1	T543	T543M	543	Missense	central	0	yes	3.666	0.000	EPSD	GDSC	3.516	Loss
AGC_PDK1_PDPK1_ST	O60331	PIP5K1C	O15530	PDPK1	T543	R550G	550	Missense	distal	7	no	3.666	3.320	EPSD	GDSC	3.516	Loss
AGC_PDK1_PDPK1_ST	Q96BR1	SGK3	O15530	PDPK1	T320	T317N	317	Missense	distal	-3	no	11.046	10.505	PhosphoSitePlus	GDSC;CCLE	3.516	Down-regulation
AGC_PDK1_PDPK1_ST	P36507	MAP2K2	O15530	PDPK1	S226	S222C	222	Missense	distal	-4	no	8.691	8.765	PhosphoSitePlus	GDSC;CCLE	3.516	Up-regulation
AGC_PDK1_PDPK1_ST	Q13153	PAK1	O15530	PDPK1	T167	A163V	163	Missense	distal	-4	no	5.260	5.263	EPSD	GDSC;CCLE	3.516	Up-regulation
AGC_PDK1_PDPK1_ST	Q13153	PAK1	O15530	PDPK1	S262	S259N	259	Missense	distal	-3	no	3.956	3.374	EPSD	GDSC;CCLE	3.516	Loss
AGC_PDK1_PDPK1_ST	Q05655	PRKCD	O15530	PDPK1	S302	S304P	304	Missense	proximal	2	no	4.135	4.088	EPSD	GDSC;CCLE	3.516	Down-regulation
AGC_PDK1_PDPK1_ST	Q05655	PRKCD	O15530	PDPK1	T451	F452S	452	Missense	proximal	1	no	4.677	1.340	EPSD	GDSC	3.516	Loss
AGC_PDK1_PDPK1_ST	Q05655	PRKCD	O15530	PDPK1	T451	R444C	444	Missense	distal	-7	no	4.677	3.952	EPSD	GDSC;CCLE	3.516	Down-regulation
AGC_PDK1_PDPK1_ST	Q05655	PRKCD	O15530	PDPK1	T451	R449H	449	Missense	proximal	-2	no	4.677	4.648	EPSD	GDSC;CCLE	3.516	Down-regulation
AGC_PDK1_PDPK1_ST	Q99683	MAP3K5	O15530	PDPK1	S83	S83C	83	Missense	central	0	yes	5.317	0.000	EPSD	GDSC;CCLE	3.516	Loss
AGC_PDK1_PDPK1_ST	Q99683	MAP3K5	O15530	PDPK1	S997	V993M	993	Missense	distal	-4	no	6.969	6.900	EPSD	GDSC;CCLE	3.516	Down-regulation
AGC_PDK1_PDPK1_ST	Q16513	PKN2	O15530	PDPK1	T503	F496V	496	Missense	distal	-7	no	2.640	3.771	EPSD	GDSC;CCLE	3.516	Gain
AGC_PDK1_PDPK1_ST	Q02156	PRKCE	O15530	PDPK1	S329	P330L	330	Missense	proximal	1	no	5.133	2.713	EPSD	GDSC;CCLE	3.516	Loss
AGC_PDK1_PDPK1_ST	Q02156	PRKCE	O15530	PDPK1	S337	P330L	330	Missense	distal	-7	no	6.709	5.757	EPSD	GDSC;CCLE	3.516	Down-regulation
STE_STE11_ASK_MAP3K5_ST	Q9UER7	DAXX	Q99683	MAP3K5	S176	S176A	176	Missense	central	0	yes	39.634	0.000	PhosphoSitePlus;EPSD	GDSC;CCLE	22.468	Loss
STE_STE11_ASK_MAP3K5_ST	Q9UER7	DAXX	Q99683	MAP3K5	S176	R182H	182	Missense	distal	6	no	39.634	35.988	PhosphoSitePlus;EPSD	GDSC;CCLE	22.468	Down-regulation
STE_STE11_ASK_MAP3K5_ST	Q9UER7	DAXX	Q99683	MAP3K5	S184	R182H	182	Missense	proximal	-2	no	37.891	37.953	EPSD;PhosphoSitePlus	GDSC;CCLE	22.468	Up-regulation
STE_STE11_ASK_MAP3K5_ST	Q9UER7	DAXX	Q99683	MAP3K5	S431	C427Y	427	Missense	distal	-4	no	27.260	28.316	EPSD	GDSC;CCLE	22.468	Up-regulation
STE_STE11_ASK_MAP3K5_ST	Q9UER7	DAXX	Q99683	MAP3K5	T684	D687V	687	Missense	distal	3	no	24.662	27.120	EPSD	GDSC	22.468	Up-regulation
STE_STE11_ASK_MAP3K5_ST	P46734	MAP2K3	Q99683	MAP3K5	T39	P41T	41	Missense	proximal	2	no	25.039	27.730	EPSD	GDSC;CCLE	22.468	Up-regulation
STE_STE11_ASK_MAP3K5_ST	P46734	MAP2K3	Q99683	MAP3K5	T117	V118I	118	Missense	proximal	1	no	29.389	26.755	EPSD	GDSC;CCLE	22.468	Down-regulation
STE_STE11_ASK_MAP3K5_ST	P46734	MAP2K3	Q99683	MAP3K5	S218	V216G	216	Missense	proximal	-2	no	44.183	43.737	PhosphoSitePlus	GDSC;CCLE	22.468	Down-regulation
STE_STE11_ASK_MAP3K5_ST	P46734	MAP2K3	Q99683	MAP3K5	S218	D217E	217	Missense	proximal	-1	no	44.183	44.648	PhosphoSitePlus	GDSC;CCLE	22.468	Up-regulation
STE_STE11_ASK_MAP3K5_ST	P46734	MAP2K3	Q99683	MAP3K5	T222	V216G	216	Missense	distal	-6	no	33.198	33.014	EPSD	GDSC;CCLE	22.468	Down-regulation
STE_STE11_ASK_MAP3K5_ST	P46734	MAP2K3	Q99683	MAP3K5	T222	D217E	217	Missense	distal	-5	no	33.198	31.585	EPSD	GDSC;CCLE	22.468	Down-regulation
STE_STE11_ASK_MAP3K5_ST	P46734	MAP2K3	Q99683	MAP3K5	T222	K228R	228	Missense	distal	6	no	33.198	34.382	EPSD	GDSC;CCLE	22.468	Up-regulation
STE_STE11_ASK_MAP3K5_ST	P45983	MAPK8	Q99683	MAP3K5	S179	G177*	177	Missense	proximal	-2	no	29.048	29.079	EPSD	GDSC	22.468	Up-regulation
STE_STE11_ASK_MAP3K5_ST	P45983	MAPK8	Q99683	MAP3K5	T183	G177*	177	Missense	distal	-6	no	46.269	46.583	PhosphoSitePlus;EPSD	GDSC	22.468	Up-regulation
STE_STE11_ASK_MAP3K5_ST	P52564	MAP2K6	Q99683	MAP3K5	S207	S201G	201	Missense	distal	-6	no	42.328	42.593	PhosphoSitePlus	GDSC	22.468	Up-regulation
STE_STE11_ASK_MAP3K5_ST	Q99683	MAP3K5	Q99683	MAP3K5	S267	S267R	267	Missense	central	0	yes	35.185	0.000	EPSD	GDSC	22.468	Loss
STE_STE11_ASK_MAP3K5_ST	Q99683	MAP3K5	Q99683	MAP3K5	S267	L260P	260	Missense	distal	-7	no	35.185	35.784	EPSD	GDSC;CCLE	22.468	Up-regulation
STE_STE11_ASK_MAP3K5_ST	Q99683	MAP3K5	Q99683	MAP3K5	S267	A266T	266	Missense	proximal	-1	no	35.185	35.896	EPSD	GDSC;CCLE	22.468	Up-regulation
STE_STE11_ASK_MAP3K5_ST	Q99683	MAP3K5	Q99683	MAP3K5	S269	S267R	267	Missense	proximal	-2	no	26.107	25.409	EPSD	GDSC	22.468	Down-regulation
STE_STE11_ASK_MAP3K5_ST	Q99683	MAP3K5	Q99683	MAP3K5	S269	A266T	266	Missense	distal	-3	no	26.107	24.582	EPSD	GDSC;CCLE	22.468	Down-regulation
STE_STE11_ASK_MAP3K5_ST	Q99683	MAP3K5	Q99683	MAP3K5	T1015	F1017L	1017	Missense	proximal	2	no	27.659	28.161	EPSD	GDSC;CCLE	22.468	Up-regulation
STE_STE11_ASK_MAP3K5_ST	Q9Y3F4	STRAP	Q99683	MAP3K5	T175	N181T	181	Missense	distal	6	no	35.430	32.241	PhosphoSitePlus;EPSD	GDSC	22.468	Down-regulation
STE_STE11_ASK_MAP3K5_ST	Q9Y3F4	STRAP	Q99683	MAP3K5	S179	N181T	181	Missense	proximal	2	no	42.363	43.861	EPSD;PhosphoSitePlus	GDSC	22.468	Up-regulation
STE_STE11_ASK_MAP3K5_ST	Q9Y3F4	STRAP	Q99683	MAP3K5	S254	Y248C	248	Missense	distal	-6	no	26.920	26.960	EPSD	GDSC;CCLE	22.468	Up-regulation
STE_STE11_ASK_MAP3K5_ST	Q969S3	ZNF622	Q99683	MAP3K5	T318	Q322R	322	Missense	distal	4	no	38.038	39.536	PhosphoSitePlus;EPSD	GDSC;CCLE	22.468	Up-regulation
STE_STE11_ASK_MAP3K5_ST	Q15691	MAPRE1	Q99683	MAP3K5	T206	V202I	202	Missense	distal	-4	no	41.243	41.694	PhosphoSitePlus;EPSD	GDSC;CCLE	22.468	Up-regulation
STE_STE11_ASK_MAP3K5_ST	O15530	PDPK1	Q99683	MAP3K5	S396	G403D	403	Missense	distal	7	no	25.082	24.728	EPSD	GDSC;CCLE	22.468	Down-regulation
STE_STE11_ASK_MAP3K5_ST	O15530	PDPK1	Q99683	MAP3K5	S396	T402A	402	Missense	distal	6	no	25.082	22.563	EPSD	GDSC;CCLE	22.468	Down-regulation
STE_STE11_ASK_MAP3K5_ST	O15530	PDPK1	Q99683	MAP3K5	S398	G403D	403	Missense	distal	5	no	40.770	41.902	PhosphoSitePlus;EPSD	GDSC;CCLE	22.468	Up-regulation
STE_STE11_ASK_MAP3K5_ST	O15530	PDPK1	Q99683	MAP3K5	S398	T402A	402	Missense	distal	4	no	40.770	39.594	PhosphoSitePlus;EPSD	GDSC;CCLE	22.468	Down-regulation
STE_STE11_ASK_MAP3K5_ST	P45985	MAP2K4	Q99683	MAP3K5	S83	S80I	80	Missense	distal	-3	no	21.414	23.004	EPSD	GDSC;CCLE	22.468	Gain
TK_VEGFR_KDR_Y	P35968	KDR	P35968	KDR	Y951	D950H	950	Missense	proximal	-1	no	75.999	75.980	PhosphoSitePlus;EPSD	GDSC	61.410	Down-regulation
TK_VEGFR_KDR_Y	P35968	KDR	P35968	KDR	Y951	D958Y	958	Missense	distal	7	no	75.999	73.210	PhosphoSitePlus;EPSD	GDSC;CCLE	61.410	Down-regulation
TK_VEGFR_KDR_Y	P35968	KDR	P35968	KDR	Y1175	V1177L	1177	Missense	proximal	2	no	74.229	75.382	EPSD;PhosphoSitePlus	GDSC;CCLE	61.410	Up-regulation
TK_VEGFR_KDR_Y	P35968	KDR	P35968	KDR	Y1214	H1213Q	1213	Missense	proximal	-1	no	92.464	92.537	EPSD;PhosphoSitePlus	GDSC;CCLE	61.410	Up-regulation
TK_VEGFR_KDR_Y	P35968	KDR	P35968	KDR	Y1214	V1207E	1207	Missense	distal	-7	no	92.464	86.802	EPSD;PhosphoSitePlus	GDSC;CCLE	61.410	Down-regulation
TK_VEGFR_KDR_Y	P35968	KDR	P35968	KDR	Y1214	F1212C	1212	Missense	proximal	-2	no	92.464	84.260	EPSD;PhosphoSitePlus	GDSC;CCLE	61.410	Down-regulation
AGC_GRK_GRK_GRK5_ST	P07550	ADRB2	P34947	GRK5	S261	T254S	254	Missense	distal	-7	no	2.394	2.441	EPSD	GDSC;CCLE	1.854	Up-regulation
AGC_GRK_GRK_GRK5_ST	P07550	ADRB2	P34947	GRK5	S261	R259C	259	Missense	proximal	-2	no	2.394	2.376	EPSD	GDSC;CCLE	1.854	Down-regulation
AGC_GRK_GRK_GRK5_ST	P26038	MSN	P34947	GRK5	T510	R517H	517	Missense	distal	7	no	2.188	2.161	EPSD	GDSC;CCLE	1.854	Down-regulation
AGC_GRK_GRK_GRK5_ST	P04637	TP53	P34947	GRK5	S33	Q38*	38	Missense	distal	5	no	3.196	3.088	EPSD	GDSC	1.854	Down-regulation
AGC_GRK_GRK_GRK5_ST	P04637	TP53	P34947	GRK5	S37	Q38*	38	Missense	proximal	1	no	2.381	2.237	EPSD	GDSC	1.854	Down-regulation
AGC_GRK_GRK_GRK5_ST	P04637	TP53	P34947	GRK5	T55	E56*	56	Missense	proximal	1	no	4.317	3.759	PhosphoSitePlus	GDSC	1.854	Down-regulation
AGC_GRK_GRK_GRK5_ST	P04637	TP53	P34947	GRK5	T55	E62*	62	Missense	distal	7	no	4.317	4.196	PhosphoSitePlus	GDSC	1.854	Down-regulation
AGC_GRK_GRK_GRK5_ST	P04637	TP53	P34947	GRK5	S313	R306*	306	Missense	distal	-7	no	1.908	1.771	EPSD	GDSC	1.854	Loss
AGC_GRK_GRK_GRK5_ST	P04637	TP53	P34947	GRK5	S313	Q317*	317	Missense	distal	4	no	1.908	1.909	EPSD	GDSC	1.854	Up-regulation
AGC_GRK_GRK_GRK5_ST	P04637	TP53	P34947	GRK5	S313	K319*	319	Missense	distal	6	no	1.908	1.925	EPSD	GDSC	1.854	Up-regulation
AGC_GRK_GRK_GRK5_ST	P37840	SNCA	P34947	GRK5	S129	E130G	130	Missense	proximal	1	no	1.896	1.415	PhosphoSitePlus	GDSC	1.854	Loss
CMGC_CK2_CSNK2A2_ST	P18887	XRCC1	P19784	CSNK2A2	S13	D16Y	16	Missense	distal	3	no	0.001	0.000	EPSD	GDSC	0.001	Loss
CMGC_CK2_CSNK2A2_ST	P35222	CTNNB1	P19784	CSNK2A2	T112	D115Y	115	Missense	distal	3	no	0.001	0.000	PhosphoSitePlus;EPSD	GDSC;CCLE	0.001	Loss
CMGC_CK2_CSNK2A2_ST	Q9UQE7	SMC3	P19784	CSNK2A2	T665	Y668D	668	Missense	distal	3	no	0.000	0.001	EPSD	GDSC;CCLE	0.001	Gain
CMGC_CK2_CSNK2A2_ST	P51946	CCNH	P19784	CSNK2A2	S132	G135E	135	Missense	distal	3	no	0.000	0.001	EPSD	GDSC;CCLE	0.001	Gain
TKL_LRRK_LRRK2_ST	Q5S007	LRRK2	Q5S007	LRRK2	T358	A356T	356	Missense	proximal	-2	no	16.532	16.395	EPSD	GDSC;CCLE	15.080	Down-regulation
TKL_LRRK_LRRK2_ST	Q5S007	LRRK2	Q5S007	LRRK2	T358	N363H	363	Missense	distal	5	no	16.532	16.244	EPSD	GDSC;CCLE	15.080	Down-regulation
TKL_LRRK_LRRK2_ST	Q5S007	LRRK2	Q5S007	LRRK2	T424	S423P	423	Missense	proximal	-1	no	17.358	17.901	EPSD;PhosphoSitePlus	GDSC;CCLE	15.080	Up-regulation
TKL_LRRK_LRRK2_ST	Q5S007	LRRK2	Q5S007	LRRK2	T524	E522V	522	Missense	proximal	-2	no	17.972	17.675	EPSD;PhosphoSitePlus	GDSC;CCLE	15.080	Down-regulation
TKL_LRRK_LRRK2_ST	Q5S007	LRRK2	Q5S007	LRRK2	T524	E519*	519	Missense	distal	-5	no	17.972	17.623	EPSD;PhosphoSitePlus	GDSC	15.080	Down-regulation
TKL_LRRK_LRRK2_ST	Q5S007	LRRK2	Q5S007	LRRK2	T776	R772*	772	Missense	distal	-4	no	16.256	13.529	EPSD;PhosphoSitePlus	GDSC	15.080	Loss
TKL_LRRK_LRRK2_ST	Q5S007	LRRK2	Q5S007	LRRK2	T776	V771I	771	Missense	distal	-5	no	16.256	16.389	EPSD;PhosphoSitePlus	GDSC;CCLE	15.080	Up-regulation
TKL_LRRK_LRRK2_ST	Q5S007	LRRK2	Q5S007	LRRK2	S954	R948*	948	Missense	distal	-6	no	13.813	17.359	EPSD	GDSC	15.080	Gain
TKL_LRRK_LRRK2_ST	Q5S007	LRRK2	Q5S007	LRRK2	S1219	L1226F	1226	Missense	distal	7	no	15.640	15.674	EPSD	GDSC;CCLE	15.080	Up-regulation
TKL_LRRK_LRRK2_ST	Q5S007	LRRK2	Q5S007	LRRK2	T1343	G1341R	1341	Missense	proximal	-2	no	16.822	16.887	EPSD;PhosphoSitePlus	GDSC	15.080	Up-regulation
TKL_LRRK_LRRK2_ST	Q5S007	LRRK2	Q5S007	LRRK2	S1345	G1341R	1341	Missense	distal	-4	no	17.472	17.461	EPSD;PhosphoSitePlus	GDSC	15.080	Down-regulation
TKL_LRRK_LRRK2_ST	Q5S007	LRRK2	Q5S007	LRRK2	T1348	G1341R	1341	Missense	distal	-7	no	17.633	18.235	EPSD;PhosphoSitePlus	GDSC	15.080	Up-regulation
TKL_LRRK_LRRK2_ST	Q5S007	LRRK2	Q5S007	LRRK2	T1368	T1368I	1368	Missense	central	0	yes	17.975	0.000	EPSD;PhosphoSitePlus	GDSC;CCLE	15.080	Loss
TKL_LRRK_LRRK2_ST	Q5S007	LRRK2	Q5S007	LRRK2	T1368	Q1365R	1365	Missense	distal	-3	no	17.975	18.064	EPSD;PhosphoSitePlus	GDSC;CCLE	15.080	Up-regulation
TKL_LRRK_LRRK2_ST	Q5S007	LRRK2	Q5S007	LRRK2	S1443	A1440P	1440	Missense	distal	-3	no	16.548	16.632	EPSD;PhosphoSitePlus	GDSC	15.080	Up-regulation
TKL_LRRK_LRRK2_ST	Q5S007	LRRK2	Q5S007	LRRK2	S1444	G1451A	1451	Missense	distal	7	no	15.938	15.886	EPSD;PhosphoSitePlus	GDSC;CCLE	15.080	Down-regulation
TKL_LRRK_LRRK2_ST	Q5S007	LRRK2	Q5S007	LRRK2	S1444	A1440P	1440	Missense	distal	-4	no	15.938	16.593	EPSD;PhosphoSitePlus	GDSC	15.080	Up-regulation
TKL_LRRK_LRRK2_ST	Q5S007	LRRK2	Q5S007	LRRK2	S1445	G1451A	1451	Missense	distal	6	no	15.500	15.225	EPSD;PhosphoSitePlus	GDSC;CCLE	15.080	Down-regulation
TKL_LRRK_LRRK2_ST	Q5S007	LRRK2	Q5S007	LRRK2	S1445	T1452I	1452	Missense	distal	7	no	15.500	15.493	EPSD;PhosphoSitePlus	GDSC;CCLE	15.080	Down-regulation
TKL_LRRK_LRRK2_ST	Q5S007	LRRK2	Q5S007	LRRK2	S1445	A1440P	1440	Missense	distal	-5	no	15.500	15.487	EPSD;PhosphoSitePlus	GDSC	15.080	Down-regulation
TKL_LRRK_LRRK2_ST	Q5S007	LRRK2	Q5S007	LRRK2	T1452	G1451A	1451	Missense	proximal	-1	no	16.299	15.826	EPSD;PhosphoSitePlus	GDSC;CCLE	15.080	Down-regulation
TKL_LRRK_LRRK2_ST	Q5S007	LRRK2	Q5S007	LRRK2	T1452	T1452I	1452	Missense	central	0	yes	16.299	0.000	EPSD;PhosphoSitePlus	GDSC;CCLE	15.080	Loss
TKL_LRRK_LRRK2_ST	Q5S007	LRRK2	Q5S007	LRRK2	T1452	V1456A	1456	Missense	distal	4	no	16.299	16.253	EPSD;PhosphoSitePlus	GDSC;CCLE	15.080	Down-regulation
TKL_LRRK_LRRK2_ST	Q5S007	LRRK2	Q5S007	LRRK2	S1457	G1451A	1451	Missense	distal	-6	no	16.050	16.554	EPSD;PhosphoSitePlus	GDSC;CCLE	15.080	Up-regulation
TKL_LRRK_LRRK2_ST	Q5S007	LRRK2	Q5S007	LRRK2	S1457	T1452I	1452	Missense	distal	-5	no	16.050	16.129	EPSD;PhosphoSitePlus	GDSC;CCLE	15.080	Up-regulation
TKL_LRRK_LRRK2_ST	Q5S007	LRRK2	Q5S007	LRRK2	S1457	V1456A	1456	Missense	proximal	-1	no	16.050	17.167	EPSD;PhosphoSitePlus	GDSC;CCLE	15.080	Up-regulation
TKL_LRRK_LRRK2_ST	Q5S007	LRRK2	Q5S007	LRRK2	S1721	R1728L	1728	Missense	distal	7	no	15.528	15.556	EPSD	GDSC;CCLE	15.080	Up-regulation
TKL_LRRK_LRRK2_ST	Q5S007	LRRK2	Q5S007	LRRK2	T1967	L1966F	1966	Missense	proximal	-1	no	17.155	16.129	EPSD;PhosphoSitePlus	GDSC;CCLE	15.080	Down-regulation
TKL_LRRK_LRRK2_ST	Q5S007	LRRK2	Q5S007	LRRK2	T1969	L1966F	1966	Missense	distal	-3	no	18.241	18.214	EPSD;PhosphoSitePlus	GDSC;CCLE	15.080	Down-regulation
TKL_LRRK_LRRK2_ST	Q5S007	LRRK2	Q5S007	LRRK2	T2483	Q2490K	2490	Missense	distal	7	no	19.727	19.745	EPSD;PhosphoSitePlus	GDSC;CCLE	15.080	Up-regulation
TKL_LRRK_LRRK2_ST	Q5S007	LRRK2	Q5S007	LRRK2	T2483	Q2484H	2484	Missense	proximal	1	no	19.727	19.765	EPSD;PhosphoSitePlus	GDSC;CCLE	15.080	Up-regulation
TKL_LRRK_LRRK2_ST	O75061	DNAJC6	Q5S007	LRRK2	S563	R561H	561	Missense	proximal	-2	no	15.673	15.890	EPSD	GDSC	15.080	Up-regulation
TKL_LRRK_LRRK2_ST	O75061	DNAJC6	Q5S007	LRRK2	S563	S563Y	563	Missense	central	0	yes	15.673	0.000	EPSD	GDSC;CCLE	15.080	Loss
TKL_LRRK_LRRK2_ST	O75061	DNAJC6	Q5S007	LRRK2	S570	S563Y	563	Missense	distal	-7	no	17.746	17.093	PhosphoSitePlus	GDSC;CCLE	15.080	Down-regulation
TKL_LRRK_LRRK2_ST	O75061	DNAJC6	Q5S007	LRRK2	S708	P706H	706	Missense	proximal	-2	no	16.869	17.395	EPSD	GDSC;CCLE	15.080	Up-regulation
TKL_LRRK_LRRK2_ST	P04637	TP53	Q5S007	LRRK2	S106	Q100*	100	Missense	distal	-6	no	15.023	18.600	EPSD	GDSC	15.080	Gain
TKL_LRRK_LRRK2_ST	P04637	TP53	Q5S007	LRRK2	T304	R306*	306	Missense	proximal	2	no	17.200	14.803	EPSD;PhosphoSitePlus	GDSC	15.080	Loss
TKL_LRRK_LRRK2_ST	P04637	TP53	Q5S007	LRRK2	T304	E298*	298	Missense	distal	-6	no	17.200	20.329	EPSD;PhosphoSitePlus	GDSC	15.080	Up-regulation
TKL_LRRK_LRRK2_ST	P62280	RPS11	Q5S007	LRRK2	T28	R35W	35	Missense	distal	7	no	16.306	16.370	EPSD;PhosphoSitePlus	GDSC;CCLE	15.080	Up-regulation
TKL_LRRK_LRRK2_ST	P62280	RPS11	Q5S007	LRRK2	T54	K58N	58	Missense	distal	4	no	18.314	18.437	EPSD;PhosphoSitePlus	GDSC;CCLE	15.080	Up-regulation
TKL_LRRK_LRRK2_ST	P62280	RPS11	Q5S007	LRRK2	T78	M82T	82	Missense	distal	4	no	15.774	15.945	EPSD	GDSC;CCLE	15.080	Up-regulation
TKL_LRRK_LRRK2_ST	P62280	RPS11	Q5S007	LRRK2	T78	R84K	84	Missense	distal	6	no	15.774	15.673	EPSD	GDSC	15.080	Down-regulation
TKL_LRRK_LRRK2_ST	P31749	AKT1	Q5S007	LRRK2	T65	Q59*	59	Missense	distal	-6	no	13.124	16.700	EPSD	GDSC	15.080	Gain
TKL_LRRK_LRRK2_ST	P05067	APP	Q5S007	LRRK2	T381	H388Y	388	Missense	distal	7	no	16.467	16.437	EPSD	GDSC;CCLE	15.080	Down-regulation
TKL_LRRK_LRRK2_ST	Q13501	SQSTM1	Q5S007	LRRK2	S88	V90M	90	Missense	proximal	2	no	16.466	16.913	EPSD	GDSC;CCLE	15.080	Up-regulation
TKL_LRRK_LRRK2_ST	Q13501	SQSTM1	Q5S007	LRRK2	T164	L166I	166	Missense	proximal	2	no	17.232	17.296	EPSD	GDSC;CCLE	15.080	Up-regulation
TKL_LRRK_LRRK2_ST	Q13501	SQSTM1	Q5S007	LRRK2	T221	G214R	214	Missense	distal	-7	no	15.108	15.710	EPSD	GDSC	15.080	Up-regulation
TKL_LRRK_LRRK2_ST	Q13501	SQSTM1	Q5S007	LRRK2	T221	P220L	220	Missense	proximal	-1	no	15.108	15.645	EPSD	GDSC;CCLE	15.080	Up-regulation
TKL_LRRK_LRRK2_ST	Q13501	SQSTM1	Q5S007	LRRK2	S276	T269A	269	Missense	distal	-7	no	15.308	15.225	EPSD	GDSC;CCLE	15.080	Down-regulation
TKL_LRRK_LRRK2_ST	Q13501	SQSTM1	Q5S007	LRRK2	S276	E274K	274	Missense	proximal	-2	no	15.308	15.537	EPSD	GDSC;CCLE	15.080	Up-regulation
TKL_LRRK_LRRK2_ST	Q13501	SQSTM1	Q5S007	LRRK2	S349	Q354*	354	Missense	distal	5	no	12.740	15.291	EPSD	GDSC	15.080	Gain
CAMK_CAMKL_QIK_SIK1_ST	Q9Y618	NCOR2	P57059	SIK1	S88	E94G	94	Missense	distal	6	no	7.042	7.379	EPSD	GDSC;CCLE	6.412	Up-regulation
CAMK_CAMKL_QIK_SIK1_ST	Q9Y618	NCOR2	P57059	SIK1	S373	R367C	367	Missense	distal	-6	no	6.811	6.760	EPSD	GDSC;CCLE	6.412	Down-regulation
CAMK_CAMKL_QIK_SIK1_ST	Q9Y618	NCOR2	P57059	SIK1	S373	L379P	379	Missense	distal	6	no	6.811	7.240	EPSD	GDSC;CCLE	6.412	Up-regulation
CAMK_CAMKL_QIK_SIK1_ST	Q9Y618	NCOR2	P57059	SIK1	S433	M431T	431	Missense	proximal	-2	no	7.081	8.131	EPSD	GDSC;CCLE	6.412	Up-regulation
CAMK_CAMKL_QIK_SIK1_ST	Q9Y618	NCOR2	P57059	SIK1	S433	R426C	426	Missense	distal	-7	no	7.081	7.052	EPSD	GDSC;CCLE	6.412	Down-regulation
CMGC_MAPK_p38_MAPK14_ST	P49023	PXN	Q16539	MAPK14	S83	V87E	87	Missense	distal	4	no	4.709	5.948	EPSD	GDSC	5.915	Gain
CMGC_MAPK_p38_MAPK14_ST	P49023	PXN	Q16539	MAPK14	S85	S83F	83	Missense	proximal	-2	no	8.951	8.227	PhosphoSitePlus	GDSC	5.915	Down-regulation
CMGC_MAPK_p38_MAPK14_ST	P49023	PXN	Q16539	MAPK14	S85	V87E	87	Missense	proximal	2	no	8.951	9.343	PhosphoSitePlus	GDSC	5.915	Up-regulation
CMGC_MAPK_p38_MAPK14_ST	P49023	PXN	Q16539	MAPK14	S91	V87E	87	Missense	distal	-4	no	7.350	6.728	EPSD	GDSC	5.915	Down-regulation
CMGC_MAPK_p38_MAPK14_ST	P49023	PXN	Q16539	MAPK14	S130	P129L	129	Missense	proximal	-1	no	9.787	9.973	EPSD	GDSC	5.915	Up-regulation
CMGC_MAPK_p38_MAPK14_ST	P49023	PXN	Q16539	MAPK14	S188	G191R	191	Missense	distal	3	no	10.832	10.818	EPSD	GDSC;CCLE	5.915	Down-regulation
CMGC_MAPK_p38_MAPK14_ST	P49023	PXN	Q16539	MAPK14	S188	S188R	188	Missense	central	0	yes	10.832	0.000	EPSD	GDSC	5.915	Loss
CMGC_MAPK_p38_MAPK14_ST	P49023	PXN	Q16539	MAPK14	S303	R301G	301	Missense	proximal	-2	no	9.882	9.632	EPSD	GDSC	5.915	Down-regulation
CMGC_MAPK_p38_MAPK14_ST	P49023	PXN	Q16539	MAPK14	S303	S302G	302	Missense	proximal	-1	no	9.882	10.095	EPSD	GDSC	5.915	Up-regulation
CMGC_MAPK_p38_MAPK14_ST	P49023	PXN	Q16539	MAPK14	S303	G305R	305	Missense	proximal	2	no	9.882	9.966	EPSD	GDSC	5.915	Up-regulation
CMGC_MAPK_p38_MAPK14_ST	P49023	PXN	Q16539	MAPK14	S322	S321N	321	Missense	proximal	-1	no	10.603	10.674	EPSD	GDSC;CCLE	5.915	Up-regulation
CMGC_MAPK_p38_MAPK14_ST	Q02078	MEF2A	Q16539	MAPK14	T108	P109T	109	Missense	proximal	1	no	12.793	5.340	EPSD;PhosphoSitePlus	GDSC	5.915	Loss
CMGC_MAPK_p38_MAPK14_ST	Q02078	MEF2A	Q16539	MAPK14	S255	M251I	251	Missense	distal	-4	no	10.492	10.588	EPSD	GDSC	5.915	Up-regulation
CMGC_MAPK_p38_MAPK14_ST	P04150	NR3C1	Q16539	MAPK14	S47	Q53H	53	Missense	distal	6	no	7.746	7.627	EPSD	GDSC;CCLE	5.915	Down-regulation
CMGC_MAPK_p38_MAPK14_ST	P19634	SLC9A1	Q16539	MAPK14	T68	R72H	72	Missense	distal	4	no	12.510	12.117	EPSD	GDSC;CCLE	5.915	Down-regulation
CMGC_MAPK_p38_MAPK14_ST	P19634	SLC9A1	Q16539	MAPK14	S693	P694L	694	Missense	proximal	1	no	10.047	1.996	EPSD	GDSC;CCLE	5.915	Loss
CMGC_MAPK_p38_MAPK14_ST	P19634	SLC9A1	Q16539	MAPK14	S703	A707V	707	Missense	distal	4	no	6.509	6.075	EPSD	GDSC;CCLE	5.915	Down-regulation
CMGC_MAPK_p38_MAPK14_ST	P19634	SLC9A1	Q16539	MAPK14	S723	P724L	724	Missense	proximal	1	no	11.402	3.352	EPSD;PhosphoSitePlus	GDSC;CCLE	5.915	Loss
CMGC_MAPK_p38_MAPK14_ST	P19634	SLC9A1	Q16539	MAPK14	S726	P724L	724	Missense	proximal	-2	no	10.305	8.925	PhosphoSitePlus;EPSD	GDSC;CCLE	5.915	Down-regulation
CMGC_MAPK_p38_MAPK14_ST	P19634	SLC9A1	Q16539	MAPK14	S729	P724L	724	Missense	distal	-5	no	6.960	7.241	EPSD;PhosphoSitePlus	GDSC;CCLE	5.915	Up-regulation
CMGC_MAPK_p38_MAPK14_ST	P15336	ATF2	Q16539	MAPK14	T69	V63A	63	Missense	distal	-6	no	11.101	11.589	PhosphoSitePlus;EPSD	GDSC;CCLE	5.915	Up-regulation
CMGC_MAPK_p38_MAPK14_ST	P15336	ATF2	Q16539	MAPK14	S136	Q134H	134	Missense	proximal	-2	no	8.563	7.312	EPSD	GDSC;CCLE	5.915	Down-regulation
CMGC_MAPK_p38_MAPK14_ST	P15336	ATF2	Q16539	MAPK14	T325	H331L	331	Missense	distal	6	no	9.210	9.190	EPSD	GDSC;CCLE	5.915	Down-regulation
CMGC_MAPK_p38_MAPK14_ST	P15336	ATF2	Q16539	MAPK14	S328	H331L	331	Missense	distal	3	no	11.961	11.937	EPSD	GDSC;CCLE	5.915	Down-regulation
CMGC_MAPK_p38_MAPK14_ST	P15336	ATF2	Q16539	MAPK14	T333	H331L	331	Missense	proximal	-2	no	10.979	11.866	EPSD	GDSC;CCLE	5.915	Up-regulation
CMGC_MAPK_p38_MAPK14_ST	P15336	ATF2	Q16539	MAPK14	T336	R342H	342	Missense	distal	6	no	6.363	6.256	EPSD	GDSC;CCLE	5.915	Down-regulation
CMGC_MAPK_p38_MAPK14_ST	P15336	ATF2	Q16539	MAPK14	T336	H331L	331	Missense	distal	-5	no	6.363	6.331	EPSD	GDSC;CCLE	5.915	Down-regulation
CMGC_MAPK_p38_MAPK14_ST	Q9NRR4	DROSHA	Q16539	MAPK14	S255	R250Q	250	Missense	distal	-5	no	9.921	9.878	PhosphoSitePlus;EPSD	GDSC;CCLE	5.915	Down-regulation
CMGC_MAPK_p38_MAPK14_ST	Q9NRR4	DROSHA	Q16539	MAPK14	S300	D296G	296	Missense	distal	-4	no	12.619	12.124	EPSD;PhosphoSitePlus	GDSC;CCLE	5.915	Down-regulation
CMGC_MAPK_p38_MAPK14_ST	Q9NRR4	DROSHA	Q16539	MAPK14	S300	R305M	305	Missense	distal	5	no	12.619	12.451	EPSD;PhosphoSitePlus	GDSC;CCLE	5.915	Down-regulation
CMGC_MAPK_p38_MAPK14_ST	Q9NRR4	DROSHA	Q16539	MAPK14	T330	A327T	327	Missense	distal	-3	no	11.414	11.509	EPSD	GDSC;CCLE	5.915	Up-regulation
CMGC_MAPK_p38_MAPK14_ST	Q9NRR4	DROSHA	Q16539	MAPK14	T330	C329Y	329	Missense	proximal	-1	no	11.414	11.259	EPSD	GDSC;CCLE	5.915	Down-regulation
CMGC_MAPK_p38_MAPK14_ST	Q9NRR4	DROSHA	Q16539	MAPK14	S355	P356L	356	Missense	proximal	1	no	9.148	1.097	EPSD;PhosphoSitePlus	GDSC;CCLE	5.915	Loss
CMGC_MAPK_p38_MAPK14_ST	Q99958	FOXC2	Q16539	MAPK14	S36	G33C	33	Missense	distal	-3	no	9.686	8.941	EPSD	GDSC;CCLE	5.915	Down-regulation
CMGC_MAPK_p38_MAPK14_ST	Q99958	FOXC2	Q16539	MAPK14	T197	H199D	199	Missense	proximal	2	no	13.330	13.372	EPSD	GDSC;CCLE	5.915	Up-regulation
CMGC_MAPK_p38_MAPK14_ST	Q99958	FOXC2	Q16539	MAPK14	T197	A201V	201	Missense	distal	4	no	13.330	12.896	EPSD	GDSC	5.915	Down-regulation
CMGC_MAPK_p38_MAPK14_ST	Q99958	FOXC2	Q16539	MAPK14	S219	A217V	217	Missense	proximal	-2	no	8.063	7.648	EPSD	GDSC;CCLE	5.915	Down-regulation
CMGC_MAPK_p38_MAPK14_ST	Q99958	FOXC2	Q16539	MAPK14	S232	A236T	236	Missense	distal	4	no	10.614	10.658	EPSD	GDSC	5.915	Up-regulation
CMGC_MAPK_p38_MAPK14_ST	Q99958	FOXC2	Q16539	MAPK14	S235	A236T	236	Missense	proximal	1	no	6.420	5.285	EPSD	GDSC	5.915	Loss
CMGC_MAPK_p38_MAPK14_ST	Q99958	FOXC2	Q16539	MAPK14	S240	A236T	236	Missense	distal	-4	no	9.958	10.195	EPSD	GDSC	5.915	Up-regulation
CMGC_MAPK_p38_MAPK14_ST	Q99958	FOXC2	Q16539	MAPK14	T484	Y481C	481	Missense	distal	-3	no	10.131	9.342	EPSD	GDSC;CCLE	5.915	Down-regulation
CMGC_MAPK_p38_MAPK14_ST	Q99958	FOXC2	Q16539	MAPK14	T484	Y488C	488	Missense	distal	4	no	10.131	10.027	EPSD	GDSC	5.915	Down-regulation
CMGC_MAPK_p38_MAPK14_ST	Q99958	FOXC2	Q16539	MAPK14	T484	S483Y	483	Missense	proximal	-1	no	10.131	10.132	EPSD	GDSC;CCLE	5.915	Up-regulation
CMGC_MAPK_p38_MAPK14_ST	P36956	SREBF1	Q16539	MAPK14	T105	P99T	99	Missense	distal	-6	no	9.499	9.834	EPSD	GDSC	5.915	Up-regulation
CMGC_MAPK_p38_MAPK14_ST	P36956	SREBF1	Q16539	MAPK14	S386	L387P	387	Missense	proximal	1	no	3.112	11.163	EPSD	GDSC	5.915	Gain
CMGC_MAPK_p38_MAPK14_ST	P38936	CDKN1A	Q16539	MAPK14	T57	E56*	56	Missense	proximal	-1	no	8.710	9.043	EPSD;PhosphoSitePlus	GDSC	5.915	Up-regulation
CMGC_MAPK_p38_MAPK14_ST	Q15750	TAB1	Q16539	MAPK14	S339	R333W	333	Missense	distal	-6	no	6.260	4.942	EPSD	GDSC;CCLE	5.915	Loss
CMGC_MAPK_p38_MAPK14_ST	Q15750	TAB1	Q16539	MAPK14	S453	S457Y	457	Missense	distal	4	no	6.000	4.953	EPSD;PhosphoSitePlus	GDSC;CCLE	5.915	Loss
CMGC_MAPK_p38_MAPK14_ST	P78536	ADAM17	Q16539	MAPK14	S266	D259H	259	Missense	distal	-7	no	7.242	7.209	EPSD	GDSC;CCLE	5.915	Down-regulation
CMGC_MAPK_p38_MAPK14_ST	P78536	ADAM17	Q16539	MAPK14	S819	K820R	820	Missense	proximal	1	no	5.595	6.667	EPSD	GDSC;CCLE	5.915	Gain
CMGC_MAPK_p38_MAPK14_ST	Q14721	KCNB1	Q16539	MAPK14	S496	E497K	497	Missense	proximal	1	no	6.348	5.100	EPSD	GDSC;CCLE	5.915	Loss
CMGC_MAPK_p38_MAPK14_ST	Q14721	KCNB1	Q16539	MAPK14	S503	E497K	497	Missense	distal	-6	no	7.680	7.266	EPSD	GDSC;CCLE	5.915	Down-regulation
CMGC_MAPK_p38_MAPK14_ST	Q14721	KCNB1	Q16539	MAPK14	S607	H606R	606	Missense	proximal	-1	no	7.581	7.426	EPSD	GDSC;CCLE	5.915	Down-regulation
CMGC_MAPK_p38_MAPK14_ST	Q14721	KCNB1	Q16539	MAPK14	S607	S607N	607	Missense	central	0	yes	7.581	0.000	EPSD	GDSC;CCLE	5.915	Loss
CMGC_MAPK_p38_MAPK14_ST	Q14721	KCNB1	Q16539	MAPK14	S656	H649Q	649	Missense	distal	-7	no	9.831	10.032	EPSD	GDSC;CCLE	5.915	Up-regulation
CMGC_MAPK_p38_MAPK14_ST	Q14721	KCNB1	Q16539	MAPK14	S737	T742R	742	Missense	distal	5	no	11.876	11.732	EPSD	GDSC;CCLE	5.915	Down-regulation
CMGC_MAPK_p38_MAPK14_ST	Q14721	KCNB1	Q16539	MAPK14	S783	T782A	782	Missense	proximal	-1	no	12.078	12.021	EPSD	GDSC;CCLE	5.915	Down-regulation
CMGC_MAPK_p38_MAPK14_ST	Q14721	KCNB1	Q16539	MAPK14	S800	N795T	795	Missense	distal	-5	no	11.299	11.276	PhosphoSitePlus;EPSD	GDSC;CCLE	5.915	Down-regulation
CMGC_MAPK_p38_MAPK14_ST	P28324	ELK4	Q16539	MAPK14	S180	P181A	181	Missense	proximal	1	no	10.005	3.687	EPSD	GDSC;CCLE	5.915	Loss
CMGC_MAPK_p38_MAPK14_ST	P28324	ELK4	Q16539	MAPK14	T185	P181A	181	Missense	distal	-4	no	9.966	9.919	EPSD	GDSC;CCLE	5.915	Down-regulation
CMGC_MAPK_p38_MAPK14_ST	P28324	ELK4	Q16539	MAPK14	S215	I210V	210	Missense	distal	-5	no	12.470	12.674	EPSD	GDSC	5.915	Up-regulation
CMGC_MAPK_p38_MAPK14_ST	P04792	HSPB1	Q16539	MAPK14	S43	R37G	37	Missense	distal	-6	no	8.128	7.753	EPSD	GDSC;CCLE	5.915	Down-regulation
CMGC_MAPK_p38_MAPK14_ST	P04792	HSPB1	Q16539	MAPK14	S154	S155P	155	Missense	proximal	1	no	2.793	10.077	EPSD	GDSC;CCLE	5.915	Gain
CMGC_MAPK_p38_MAPK14_ST	P04792	HSPB1	Q16539	MAPK14	S158	S155P	155	Missense	distal	-3	no	14.484	13.720	EPSD	GDSC;CCLE	5.915	Down-regulation
CMGC_MAPK_p38_MAPK14_ST	P04792	HSPB1	Q16539	MAPK14	S199	A203S	203	Missense	distal	4	no	7.301	7.607	EPSD	GDSC;CCLE	5.915	Up-regulation
CMGC_MAPK_p38_MAPK14_ST	P04792	HSPB1	Q16539	MAPK14	S199	A204S	204	Missense	distal	5	no	7.301	7.940	EPSD	GDSC;CCLE	5.915	Up-regulation
CMGC_MAPK_p38_MAPK14_ST	P03372	ESR1	Q16539	MAPK14	S294	K299N	299	Missense	distal	5	no	9.793	10.063	EPSD;PhosphoSitePlus	GDSC;CCLE	5.915	Up-regulation
CMGC_MAPK_p38_MAPK14_ST	P03372	ESR1	Q16539	MAPK14	S294	I298V	298	Missense	distal	4	no	9.793	9.842	EPSD;PhosphoSitePlus	GDSC	5.915	Up-regulation
CMGC_MAPK_p38_MAPK14_ST	Q9H3D4	TP63	Q16539	MAPK14	S160	T155I	155	Missense	distal	-5	no	12.600	12.558	EPSD	GDSC;CCLE	5.915	Down-regulation
CMGC_MAPK_p38_MAPK14_ST	Q9H3D4	TP63	Q16539	MAPK14	S162	T155I	155	Missense	distal	-7	no	9.524	9.173	EPSD	GDSC;CCLE	5.915	Down-regulation
CMGC_MAPK_p38_MAPK14_ST	Q9H3D4	TP63	Q16539	MAPK14	S455	S457P	457	Missense	proximal	2	no	10.132	9.755	EPSD	GDSC	5.915	Down-regulation
CMGC_MAPK_p38_MAPK14_ST	Q9H3D4	TP63	Q16539	MAPK14	S463	S457P	457	Missense	distal	-6	no	11.330	10.724	EPSD	GDSC	5.915	Down-regulation
CMGC_MAPK_p38_MAPK14_ST	Q9H3D4	TP63	Q16539	MAPK14	T491	Q485R	485	Missense	distal	-6	no	6.592	7.262	EPSD	GDSC;CCLE	5.915	Up-regulation
CMGC_MAPK_p38_MAPK14_ST	P29353	SHC1	Q16539	MAPK14	T29	P31L	31	Missense	proximal	2	no	11.108	10.995	EPSD	GDSC	5.915	Down-regulation
CMGC_MAPK_p38_MAPK14_ST	P29353	SHC1	Q16539	MAPK14	T29	S36F	36	Missense	distal	7	no	11.108	10.238	EPSD	GDSC;CCLE	5.915	Down-regulation
CMGC_MAPK_p38_MAPK14_ST	P29353	SHC1	Q16539	MAPK14	S36	P31L	31	Missense	distal	-5	no	11.449	11.730	EPSD	GDSC	5.915	Up-regulation
CMGC_MAPK_p38_MAPK14_ST	P29353	SHC1	Q16539	MAPK14	S36	S36F	36	Missense	central	0	yes	11.449	0.000	EPSD	GDSC;CCLE	5.915	Loss
CMGC_MAPK_p38_MAPK14_ST	P29353	SHC1	Q16539	MAPK14	S80	G82E	82	Missense	proximal	2	no	6.165	6.359	EPSD	GDSC	5.915	Up-regulation
CMGC_MAPK_p38_MAPK14_ST	P29353	SHC1	Q16539	MAPK14	S139	T145P	145	Missense	distal	6	no	8.842	8.816	EPSD	GDSC;CCLE	5.915	Down-regulation
CMGC_MAPK_p38_MAPK14_ST	P41212	ETV6	Q16539	MAPK14	S22	S26T	26	Missense	distal	4	no	12.051	11.790	EPSD;PhosphoSitePlus	GDSC	5.915	Down-regulation
CMGC_MAPK_p38_MAPK14_ST	P41212	ETV6	Q16539	MAPK14	T31	S26T	26	Missense	distal	-5	no	8.234	8.675	EPSD	GDSC	5.915	Up-regulation
CMGC_MAPK_p38_MAPK14_ST	P41212	ETV6	Q16539	MAPK14	T161	R163M	163	Missense	proximal	2	no	8.711	8.602	EPSD	GDSC	5.915	Down-regulation
CMGC_MAPK_p38_MAPK14_ST	P41212	ETV6	Q16539	MAPK14	T161	S165Y	165	Missense	distal	4	no	8.711	7.664	EPSD	GDSC;CCLE	5.915	Down-regulation
CMGC_MAPK_p38_MAPK14_ST	P41212	ETV6	Q16539	MAPK14	S213	P214S	214	Missense	proximal	1	no	9.084	1.800	EPSD	GDSC;CCLE	5.915	Loss
CMGC_MAPK_p38_MAPK14_ST	P41212	ETV6	Q16539	MAPK14	S238	N243D	243	Missense	distal	5	no	11.284	11.075	EPSD	GDSC	5.915	Down-regulation
CMGC_MAPK_p38_MAPK14_ST	P41212	ETV6	Q16539	MAPK14	S257	Q260*	260	Missense	distal	3	no	13.479	13.563	PhosphoSitePlus;EPSD	GDSC	5.915	Up-regulation
CMGC_MAPK_p38_MAPK14_ST	P41212	ETV6	Q16539	MAPK14	S257	R259L	259	Missense	proximal	2	no	13.479	13.135	PhosphoSitePlus;EPSD	GDSC;CCLE	5.915	Down-regulation
CMGC_MAPK_p38_MAPK14_ST	P41212	ETV6	Q16539	MAPK14	S257	S256F	256	Missense	proximal	-1	no	13.479	13.721	PhosphoSitePlus;EPSD	GDSC;CCLE	5.915	Up-regulation
CMGC_MAPK_p38_MAPK14_ST	P21462	FPR1	Q16539	MAPK14	S332	T325N	325	Missense	distal	-7	no	6.497	6.356	EPSD	GDSC	5.915	Down-regulation
CMGC_MAPK_p38_MAPK14_ST	Q9UBK2	PPARGC1A	Q16539	MAPK14	T299	A304V	304	Missense	distal	5	no	12.244	12.226	EPSD;PhosphoSitePlus	GDSC	5.915	Down-regulation
CMGC_MAPK_p38_MAPK14_ST	Q9UBK2	PPARGC1A	Q16539	MAPK14	S593	R598I	598	Missense	distal	5	no	7.958	7.176	EPSD	GDSC	5.915	Down-regulation
CMGC_MAPK_p38_MAPK14_ST	P49841	GSK3B	Q16539	MAPK14	T7	T8P	8	Missense	proximal	1	no	5.392	12.845	EPSD	GDSC	5.915	Gain
CMGC_MAPK_p38_MAPK14_ST	P49841	GSK3B	Q16539	MAPK14	S9	T8P	8	Missense	proximal	-1	no	6.613	6.589	EPSD	GDSC	5.915	Down-regulation
CMGC_MAPK_p38_MAPK14_ST	P49841	GSK3B	Q16539	MAPK14	T324	R319*	319	Missense	distal	-5	no	8.820	9.997	EPSD	GDSC	5.915	Up-regulation
CMGC_MAPK_p38_MAPK14_ST	O43526	KCNQ2	Q16539	MAPK14	S45	R50H	50	Missense	distal	5	no	6.123	5.429	EPSD	GDSC	5.915	Loss
CMGC_MAPK_p38_MAPK14_ST	O43526	KCNQ2	Q16539	MAPK14	S457	S457F	457	Missense	central	0	yes	8.506	0.000	EPSD	GDSC;CCLE	5.915	Loss
CMGC_MAPK_p38_MAPK14_ST	O43526	KCNQ2	Q16539	MAPK14	S457	P458L	458	Missense	proximal	1	no	8.506	0.455	EPSD	GDSC	5.915	Loss
CMGC_MAPK_p38_MAPK14_ST	O43526	KCNQ2	Q16539	MAPK14	S457	V450M	450	Missense	distal	-7	no	8.506	9.195	EPSD	GDSC	5.915	Up-regulation
CMGC_MAPK_p38_MAPK14_ST	O43526	KCNQ2	Q16539	MAPK14	S466	S468R	468	Missense	proximal	2	no	9.429	9.283	EPSD	GDSC;CCLE	5.915	Down-regulation
CMGC_MAPK_p38_MAPK14_ST	O43526	KCNQ2	Q16539	MAPK14	S468	S468R	468	Missense	central	0	yes	7.928	0.000	EPSD	GDSC;CCLE	5.915	Loss
CMGC_MAPK_p38_MAPK14_ST	O43526	KCNQ2	Q16539	MAPK14	S485	R491W	491	Missense	distal	6	no	8.297	8.033	EPSD	GDSC;CCLE	5.915	Down-regulation
CMGC_MAPK_p38_MAPK14_ST	Q9BUB5	MKNK1	Q16539	MAPK14	S460	T463I	463	Missense	distal	3	no	9.280	9.363	EPSD	GDSC;CCLE	5.915	Up-regulation
CMGC_MAPK_p38_MAPK14_ST	Q9BUB5	MKNK1	Q16539	MAPK14	S460	R455H	455	Missense	distal	-5	no	9.280	9.823	EPSD	GDSC	5.915	Up-regulation
CMGC_MAPK_p38_MAPK14_ST	Q9Y6Q9	NCOA3	Q16539	MAPK14	S465	P467Q	467	Missense	proximal	2	no	9.402	9.207	EPSD	GDSC	5.915	Down-regulation
CMGC_MAPK_p38_MAPK14_ST	Q9Y6Q9	NCOA3	Q16539	MAPK14	S465	Y459H	459	Missense	distal	-6	no	9.402	9.099	EPSD	GDSC;CCLE	5.915	Down-regulation
CMGC_MAPK_p38_MAPK14_ST	Q9Y6Q9	NCOA3	Q16539	MAPK14	S470	P467Q	467	Missense	distal	-3	no	8.685	8.182	EPSD	GDSC	5.915	Down-regulation
CMGC_MAPK_p38_MAPK14_ST	Q9Y6Q9	NCOA3	Q16539	MAPK14	S635	P641S	641	Missense	distal	6	no	6.837	6.825	EPSD	GDSC;CCLE	5.915	Down-regulation
CMGC_MAPK_p38_MAPK14_ST	Q9Y6Q9	NCOA3	Q16539	MAPK14	S640	P641S	641	Missense	proximal	1	no	11.405	4.122	EPSD	GDSC;CCLE	5.915	Loss
CMGC_MAPK_p38_MAPK14_ST	Q9Y6Q9	NCOA3	Q16539	MAPK14	S655	S657F	657	Missense	proximal	2	no	11.209	10.543	EPSD	GDSC;CCLE	5.915	Down-regulation
CMGC_MAPK_p38_MAPK14_ST	Q9Y6Q9	NCOA3	Q16539	MAPK14	S661	S657F	657	Missense	distal	-4	no	5.706	6.410	EPSD	GDSC;CCLE	5.915	Gain
CMGC_MAPK_p38_MAPK14_ST	Q9Y6Q9	NCOA3	Q16539	MAPK14	S728	V721I	721	Missense	distal	-7	no	12.582	12.866	EPSD	GDSC	5.915	Up-regulation
CMGC_MAPK_p38_MAPK14_ST	Q9Y6Q9	NCOA3	Q16539	MAPK14	T914	S917L	917	Missense	distal	3	no	10.161	10.235	EPSD	GDSC	5.915	Up-regulation
CMGC_MAPK_p38_MAPK14_ST	Q15672	TWIST1	Q16539	MAPK14	S99	E104Q	104	Missense	distal	5	no	12.310	11.689	EPSD	GDSC;CCLE	5.915	Down-regulation
CMGC_MAPK_p38_MAPK14_ST	P49137	MAPKAPK2	Q16539	MAPK14	T222	Y225H	225	Missense	distal	3	no	13.944	14.001	PhosphoSitePlus;EPSD	GDSC;CCLE	5.915	Up-regulation
CMGC_MAPK_p38_MAPK14_ST	P49137	MAPKAPK2	Q16539	MAPK14	T226	Y225H	225	Missense	proximal	-1	no	9.442	9.489	EPSD	GDSC;CCLE	5.915	Up-regulation
CMGC_MAPK_p38_MAPK14_ST	P19525	EIF2AK2	Q16539	MAPK14	S83	T90A	90	Missense	distal	7	no	7.056	7.400	EPSD	GDSC;CCLE	5.915	Up-regulation
CMGC_MAPK_p38_MAPK14_ST	P19525	EIF2AK2	Q16539	MAPK14	T90	T90A	90	Missense	central	0	yes	6.329	0.000	EPSD	GDSC;CCLE	5.915	Loss
CMGC_MAPK_p38_MAPK14_ST	P19525	EIF2AK2	Q16539	MAPK14	S181	E187K	187	Missense	distal	6	no	6.762	6.757	EPSD	GDSC;CCLE	5.915	Down-regulation
CMGC_MAPK_p38_MAPK14_ST	O75582	RPS6KA5	Q16539	MAPK14	S253	E260G	260	Missense	distal	7	no	11.620	11.259	EPSD	GDSC	5.915	Down-regulation
CMGC_MAPK_p38_MAPK14_ST	O75582	RPS6KA5	Q16539	MAPK14	S253	D258H	258	Missense	distal	5	no	11.620	11.159	EPSD	GDSC;CCLE	5.915	Down-regulation
CMGC_MAPK_p38_MAPK14_ST	O75582	RPS6KA5	Q16539	MAPK14	T581	K580R	580	Missense	proximal	-1	no	10.790	10.708	EPSD;PhosphoSitePlus	GDSC	5.915	Down-regulation
CMGC_MAPK_p38_MAPK14_ST	O75582	RPS6KA5	Q16539	MAPK14	S750	R756H	756	Missense	distal	6	no	6.200	6.092	EPSD	GDSC;CCLE	5.915	Down-regulation
CMGC_MAPK_p38_MAPK14_ST	O75582	RPS6KA5	Q16539	MAPK14	S750	T755P	755	Missense	distal	5	no	6.200	5.916	EPSD	GDSC;CCLE	5.915	Down-regulation
CMGC_MAPK_p38_MAPK14_ST	O75582	RPS6KA5	Q16539	MAPK14	S759	R756H	756	Missense	distal	-3	no	7.234	5.481	EPSD	GDSC;CCLE	5.915	Loss
CMGC_MAPK_p38_MAPK14_ST	O75582	RPS6KA5	Q16539	MAPK14	S759	T755P	755	Missense	distal	-4	no	7.234	7.045	EPSD	GDSC;CCLE	5.915	Down-regulation
CMGC_MAPK_p38_MAPK14_ST	P43403	ZAP70	Q16539	MAPK14	S167	R170C	170	Missense	distal	3	no	6.251	6.307	EPSD	GDSC;CCLE	5.915	Up-regulation
CMGC_MAPK_p38_MAPK14_ST	P43403	ZAP70	Q16539	MAPK14	S167	Y164H	164	Missense	distal	-3	no	6.251	5.904	EPSD	GDSC;CCLE	5.915	Loss
CMGC_MAPK_p38_MAPK14_ST	P43403	ZAP70	Q16539	MAPK14	T293	G291E	291	Missense	proximal	-2	no	10.107	10.785	PhosphoSitePlus	GDSC;CCLE	5.915	Up-regulation
CMGC_MAPK_p38_MAPK14_ST	P43403	ZAP70	Q16539	MAPK14	S491	Y492H	492	Missense	proximal	1	no	6.117	-0.260	EPSD	GDSC;CCLE	5.915	Loss
CMGC_MAPK_p38_MAPK14_ST	P43403	ZAP70	Q16539	MAPK14	T494	Y492H	492	Missense	proximal	-2	no	6.181	4.401	EPSD	GDSC;CCLE	5.915	Loss
CMGC_MAPK_p38_MAPK14_ST	P35236	PTPN7	Q16539	MAPK14	T66	T66A	66	Missense	central	0	yes	13.138	0.000	PhosphoSitePlus;EPSD	GDSC	5.915	Loss
CMGC_MAPK_p38_MAPK14_ST	P27816	MAP4	Q16539	MAPK14	S14	A7S	7	Missense	distal	-7	no	13.726	13.613	EPSD	GDSC;CCLE	5.915	Down-regulation
CMGC_MAPK_p38_MAPK14_ST	P27816	MAP4	Q16539	MAPK14	S94	T101A	101	Missense	distal	7	no	6.361	6.704	EPSD	GDSC	5.915	Up-regulation
CMGC_MAPK_p38_MAPK14_ST	P27816	MAP4	Q16539	MAPK14	S99	T101A	101	Missense	proximal	2	no	10.831	10.803	EPSD	GDSC	5.915	Down-regulation
CMGC_MAPK_p38_MAPK14_ST	P27816	MAP4	Q16539	MAPK14	S156	A158T	158	Missense	proximal	2	no	5.908	5.936	EPSD	GDSC;CCLE	5.915	Gain
CMGC_MAPK_p38_MAPK14_ST	P27816	MAP4	Q16539	MAPK14	S179	S179F	179	Missense	central	0	yes	10.825	0.000	EPSD	GDSC;CCLE	5.915	Loss
CMGC_MAPK_p38_MAPK14_ST	P27816	MAP4	Q16539	MAPK14	S384	P385L	385	Missense	proximal	1	no	11.088	3.037	EPSD	GDSC;CCLE	5.915	Loss
CMGC_MAPK_p38_MAPK14_ST	P27816	MAP4	Q16539	MAPK14	T521	T526A	526	Missense	distal	5	no	11.676	11.204	EPSD	GDSC	5.915	Down-regulation
CMGC_MAPK_p38_MAPK14_ST	P27816	MAP4	Q16539	MAPK14	T571	T571P	571	Missense	central	0	yes	9.086	0.000	EPSD	GDSC	5.915	Loss
CMGC_MAPK_p38_MAPK14_ST	P27816	MAP4	Q16539	MAPK14	S659	E660V	660	Missense	proximal	1	no	6.485	4.967	EPSD	GDSC;CCLE	5.915	Loss
CMGC_MAPK_p38_MAPK14_ST	P27816	MAP4	Q16539	MAPK14	S659	P653L	653	Missense	distal	-6	no	6.485	5.872	EPSD	GDSC	5.915	Loss
CMGC_MAPK_p38_MAPK14_ST	P27816	MAP4	Q16539	MAPK14	S659	S666L	666	Missense	distal	7	no	6.485	6.100	EPSD	GDSC;CCLE	5.915	Down-regulation
CMGC_MAPK_p38_MAPK14_ST	P27816	MAP4	Q16539	MAPK14	S662	E660V	660	Missense	proximal	-2	no	8.246	7.430	EPSD	GDSC;CCLE	5.915	Down-regulation
CMGC_MAPK_p38_MAPK14_ST	P27816	MAP4	Q16539	MAPK14	S662	S666L	666	Missense	distal	4	no	8.246	7.168	EPSD	GDSC;CCLE	5.915	Down-regulation
CMGC_MAPK_p38_MAPK14_ST	P27816	MAP4	Q16539	MAPK14	S666	E660V	660	Missense	distal	-6	no	6.032	5.172	EPSD	GDSC;CCLE	5.915	Loss
CMGC_MAPK_p38_MAPK14_ST	P27816	MAP4	Q16539	MAPK14	S666	S666L	666	Missense	central	0	yes	6.032	0.000	EPSD	GDSC;CCLE	5.915	Loss
CMGC_MAPK_p38_MAPK14_ST	P27816	MAP4	Q16539	MAPK14	T892	A891T	891	Missense	proximal	-1	no	8.461	8.518	EPSD	GDSC	5.915	Up-regulation
CMGC_MAPK_p38_MAPK14_ST	P27816	MAP4	Q16539	MAPK14	T901	P902L	902	Missense	proximal	1	no	8.464	0.413	EPSD	GDSC	5.915	Loss
CMGC_MAPK_p38_MAPK14_ST	Q9H211	CDT1	Q16539	MAPK14	S79	A85S	85	Missense	distal	6	no	13.678	13.624	EPSD	GDSC;CCLE	5.915	Down-regulation
CMGC_MAPK_p38_MAPK14_ST	Q9H211	CDT1	Q16539	MAPK14	S79	T82P	82	Missense	distal	3	no	13.678	13.705	EPSD	GDSC	5.915	Up-regulation
CMGC_MAPK_p38_MAPK14_ST	Q9H211	CDT1	Q16539	MAPK14	S79	P83L	83	Missense	distal	4	no	13.678	13.039	EPSD	GDSC	5.915	Down-regulation
CMGC_MAPK_p38_MAPK14_ST	Q9H211	CDT1	Q16539	MAPK14	S81	T82P	82	Missense	proximal	1	no	3.846	11.299	EPSD	GDSC	5.915	Gain
CMGC_MAPK_p38_MAPK14_ST	Q9H211	CDT1	Q16539	MAPK14	T82	A85S	85	Missense	distal	3	no	9.524	9.509	EPSD	GDSC;CCLE	5.915	Down-regulation
CMGC_MAPK_p38_MAPK14_ST	Q9H211	CDT1	Q16539	MAPK14	T82	T82P	82	Missense	central	0	yes	9.524	0.000	EPSD	GDSC	5.915	Loss
CMGC_MAPK_p38_MAPK14_ST	Q9H211	CDT1	Q16539	MAPK14	T82	P83L	83	Missense	proximal	1	no	9.524	1.473	EPSD	GDSC	5.915	Loss
CMGC_MAPK_p38_MAPK14_ST	Q9H211	CDT1	Q16539	MAPK14	S93	A90D	90	Missense	distal	-3	no	10.051	9.475	EPSD	GDSC;CCLE	5.915	Down-regulation
CMGC_MAPK_p38_MAPK14_ST	Q9H211	CDT1	Q16539	MAPK14	T152	R158H	158	Missense	distal	6	no	11.586	11.479	EPSD	GDSC	5.915	Down-regulation
CMGC_MAPK_p38_MAPK14_ST	Q9H211	CDT1	Q16539	MAPK14	T213	T213K	213	Missense	central	0	yes	9.181	0.000	EPSD	GDSC;CCLE	5.915	Loss
CMGC_MAPK_p38_MAPK14_ST	Q9H211	CDT1	Q16539	MAPK14	S318	L314M	314	Missense	distal	-4	no	11.534	11.005	EPSD	GDSC	5.915	Down-regulation
CMGC_MAPK_p38_MAPK14_ST	Q9H211	CDT1	Q16539	MAPK14	S386	A388T	388	Missense	proximal	2	no	6.324	6.353	EPSD	GDSC;CCLE	5.915	Up-regulation
CMGC_MAPK_p38_MAPK14_ST	Q9H211	CDT1	Q16539	MAPK14	S391	R396K	396	Missense	distal	5	no	11.410	11.115	PhosphoSitePlus;EPSD	GDSC	5.915	Down-regulation
CMGC_MAPK_p38_MAPK14_ST	Q9H211	CDT1	Q16539	MAPK14	S391	A388T	388	Missense	distal	-3	no	11.410	11.505	PhosphoSitePlus;EPSD	GDSC;CCLE	5.915	Up-regulation
CMGC_MAPK_p38_MAPK14_ST	Q9H211	CDT1	Q16539	MAPK14	S394	R396K	396	Missense	proximal	2	no	11.973	11.769	EPSD	GDSC	5.915	Down-regulation
CMGC_MAPK_p38_MAPK14_ST	Q9H211	CDT1	Q16539	MAPK14	S394	A388T	388	Missense	distal	-6	no	11.973	12.243	EPSD	GDSC;CCLE	5.915	Up-regulation
CMGC_MAPK_p38_MAPK14_ST	Q9H211	CDT1	Q16539	MAPK14	T402	R396K	396	Missense	distal	-6	no	11.215	10.737	EPSD;PhosphoSitePlus	GDSC	5.915	Down-regulation
CMGC_MAPK_p38_MAPK14_ST	Q00613	HSF1	Q16539	MAPK14	S292	R296H	296	Missense	distal	4	no	11.025	10.631	EPSD	GDSC;CCLE	5.915	Down-regulation
CMGC_MAPK_p38_MAPK14_ST	Q00613	HSF1	Q16539	MAPK14	S303	P308L	308	Missense	distal	5	no	12.833	12.336	EPSD;PhosphoSitePlus	GDSC	5.915	Down-regulation
CMGC_MAPK_p38_MAPK14_ST	Q00613	HSF1	Q16539	MAPK14	S303	R296H	296	Missense	distal	-7	no	12.833	12.538	EPSD;PhosphoSitePlus	GDSC;CCLE	5.915	Down-regulation
CMGC_MAPK_p38_MAPK14_ST	Q00613	HSF1	Q16539	MAPK14	S307	P308L	308	Missense	proximal	1	no	11.613	3.562	PhosphoSitePlus;EPSD	GDSC	5.915	Loss
CMGC_MAPK_p38_MAPK14_ST	Q00613	HSF1	Q16539	MAPK14	S307	E312A	312	Missense	distal	5	no	11.613	11.013	PhosphoSitePlus;EPSD	GDSC	5.915	Down-regulation
CMGC_MAPK_p38_MAPK14_ST	Q00613	HSF1	Q16539	MAPK14	S314	P308L	308	Missense	distal	-6	no	11.567	10.954	EPSD	GDSC	5.915	Down-regulation
CMGC_MAPK_p38_MAPK14_ST	Q00613	HSF1	Q16539	MAPK14	S314	E312A	312	Missense	proximal	-2	no	11.567	11.165	EPSD	GDSC	5.915	Down-regulation
CMGC_MAPK_p38_MAPK14_ST	Q00613	HSF1	Q16539	MAPK14	S363	R360Q	360	Missense	distal	-3	no	14.180	12.400	EPSD	GDSC	5.915	Down-regulation
CMGC_MAPK_p38_MAPK14_ST	Q00613	HSF1	Q16539	MAPK14	S363	R360W	360	Missense	distal	-3	no	14.180	11.822	EPSD	GDSC;CCLE	5.915	Down-regulation
CMGC_MAPK_p38_MAPK14_ST	Q00613	HSF1	Q16539	MAPK14	S419	S419R	419	Missense	central	0	yes	11.046	0.000	EPSD	GDSC	5.915	Loss
CMGC_MAPK_p38_MAPK14_ST	Q00613	HSF1	Q16539	MAPK14	S419	S421W	421	Missense	proximal	2	no	11.046	10.402	EPSD	GDSC	5.915	Down-regulation
CMGC_MAPK_p38_MAPK14_ST	Q00613	HSF1	Q16539	MAPK14	S419	V422L	422	Missense	distal	3	no	11.046	11.078	EPSD	GDSC;CCLE	5.915	Up-regulation
CMGC_MAPK_p38_MAPK14_ST	Q00613	HSF1	Q16539	MAPK14	S458	S458I	458	Missense	central	0	yes	10.291	0.000	EPSD	GDSC;CCLE	5.915	Loss
CMGC_MAPK_p38_MAPK14_ST	Q00613	HSF1	Q16539	MAPK14	S461	S458I	458	Missense	distal	-3	no	6.637	4.565	EPSD	GDSC;CCLE	5.915	Loss
CMGC_MAPK_p38_MAPK14_ST	Q9UK80	USP21	Q16539	MAPK14	S499	D495E	495	Missense	distal	-4	no	9.842	9.050	EPSD	GDSC;CCLE	5.915	Down-regulation
CMGC_MAPK_p38_MAPK14_ST	P04637	TP53	Q16539	MAPK14	S33	Q38*	38	Missense	distal	5	no	11.723	10.196	EPSD;PhosphoSitePlus	GDSC	5.915	Down-regulation
CMGC_MAPK_p38_MAPK14_ST	P04637	TP53	Q16539	MAPK14	T81	A74S	74	Missense	distal	-7	no	7.344	7.231	EPSD	GDSC;CCLE	5.915	Down-regulation
CMGC_MAPK_p38_MAPK14_ST	P04637	TP53	Q16539	MAPK14	S99	Q100*	100	Missense	proximal	1	no	3.724	6.639	EPSD	GDSC	5.915	Gain
CMGC_MAPK_p38_MAPK14_ST	P04637	TP53	Q16539	MAPK14	S127	Y126*	126	Missense	proximal	-1	no	12.191	12.436	EPSD	GDSC	5.915	Up-regulation
CMGC_MAPK_p38_MAPK14_ST	P04637	TP53	Q16539	MAPK14	S127	K120*	120	Missense	distal	-7	no	12.191	11.076	EPSD	GDSC	5.915	Down-regulation
CMGC_MAPK_p38_MAPK14_ST	P04637	TP53	Q16539	MAPK14	S149	Q144*	144	Missense	distal	-5	no	5.322	6.541	EPSD	GDSC	5.915	Gain
CMGC_MAPK_p38_MAPK14_ST	P04637	TP53	Q16539	MAPK14	T150	Q144*	144	Missense	distal	-6	no	7.036	5.798	EPSD	GDSC	5.915	Loss
CMGC_MAPK_p38_MAPK14_ST	P04637	TP53	Q16539	MAPK14	T150	W146*	146	Missense	distal	-4	no	7.036	7.108	EPSD	GDSC	5.915	Up-regulation
CMGC_MAPK_p38_MAPK14_ST	P04637	TP53	Q16539	MAPK14	T211	R213*	213	Missense	proximal	2	no	6.953	6.231	EPSD	GDSC	5.915	Down-regulation
CMGC_MAPK_p38_MAPK14_ST	P04637	TP53	Q16539	MAPK14	T211	R209*	209	Missense	proximal	-2	no	6.953	6.316	EPSD	GDSC	5.915	Down-regulation
CMGC_MAPK_p38_MAPK14_ST	P04637	TP53	Q16539	MAPK14	T211	E204*	204	Missense	distal	-7	no	6.953	5.785	EPSD	GDSC	5.915	Loss
CMGC_MAPK_p38_MAPK14_ST	P04637	TP53	Q16539	MAPK14	S315	Q317*	317	Missense	proximal	2	no	10.517	10.221	EPSD	GDSC	5.915	Down-regulation
CMGC_MAPK_p38_MAPK14_ST	P04637	TP53	Q16539	MAPK14	S315	K319*	319	Missense	distal	4	no	10.517	8.373	EPSD	GDSC	5.915	Down-regulation
CMGC_MAPK_p38_MAPK14_ST	P04637	TP53	Q16539	MAPK14	S366	G360V	360	Missense	distal	-6	no	6.617	6.067	EPSD	GDSC;CCLE	5.915	Down-regulation
CMGC_MAPK_p38_MAPK14_ST	Q9UIG0	BAZ1B	Q16539	MAPK14	S197	T203A	203	Missense	distal	6	no	10.765	10.782	EPSD	GDSC;CCLE	5.915	Up-regulation
CMGC_MAPK_p38_MAPK14_ST	Q9UIG0	BAZ1B	Q16539	MAPK14	T266	A264V	264	Missense	proximal	-2	no	5.926	5.511	EPSD	GDSC;CCLE	5.915	Loss
CMGC_MAPK_p38_MAPK14_ST	Q9UIG0	BAZ1B	Q16539	MAPK14	S329	L332V	332	Missense	distal	3	no	5.984	5.952	EPSD	GDSC;CCLE	5.915	Down-regulation
CMGC_MAPK_p38_MAPK14_ST	Q9UIG0	BAZ1B	Q16539	MAPK14	S330	L332V	332	Missense	proximal	2	no	11.853	11.914	EPSD	GDSC;CCLE	5.915	Up-regulation
CMGC_MAPK_p38_MAPK14_ST	Q9UIG0	BAZ1B	Q16539	MAPK14	S423	K425R	425	Missense	proximal	2	no	9.033	9.236	EPSD	GDSC	5.915	Up-regulation
CMGC_MAPK_p38_MAPK14_ST	Q9UIG0	BAZ1B	Q16539	MAPK14	T430	K425R	425	Missense	distal	-5	no	10.147	10.282	EPSD	GDSC	5.915	Up-regulation
CMGC_MAPK_p38_MAPK14_ST	Q9UIG0	BAZ1B	Q16539	MAPK14	S539	M538I	538	Missense	proximal	-1	no	6.099	5.953	EPSD	GDSC;CCLE	5.915	Down-regulation
CMGC_MAPK_p38_MAPK14_ST	Q9UIG0	BAZ1B	Q16539	MAPK14	S1342	S1337N	1337	Missense	distal	-5	no	6.584	7.048	EPSD	GDSC;CCLE	5.915	Up-regulation
CMGC_MAPK_p38_MAPK14_ST	Q9UIG0	BAZ1B	Q16539	MAPK14	S1361	V1356M	1356	Missense	distal	-5	no	6.703	6.252	EPSD	GDSC;CCLE	5.915	Down-regulation
CMGC_MAPK_p38_MAPK14_ST	Q15717	ELAVL1	Q16539	MAPK14	S202	S197L	197	Missense	distal	-5	no	7.397	8.126	EPSD	GDSC;CCLE	5.915	Up-regulation
CMGC_MAPK_p38_MAPK14_ST	P31645	SLC6A4	Q16539	MAPK14	S48	N45S	45	Missense	distal	-3	no	5.107	6.254	EPSD	GDSC;CCLE	5.915	Gain
CMGC_MAPK_p38_MAPK14_ST	P31645	SLC6A4	Q16539	MAPK14	S52	N45S	45	Missense	distal	-7	no	9.852	10.063	EPSD	GDSC;CCLE	5.915	Up-regulation
CMGC_MAPK_p38_MAPK14_ST	P31645	SLC6A4	Q16539	MAPK14	S52	S48L	48	Missense	distal	-4	no	9.852	10.452	EPSD	GDSC;CCLE	5.915	Up-regulation
CMGC_MAPK_p38_MAPK14_ST	Q9NQU5	PAK6	Q16539	MAPK14	S165	P159L	159	Missense	distal	-6	no	8.810	8.197	PhosphoSitePlus	GDSC	5.915	Down-regulation
CMGC_MAPK_p38_MAPK14_ST	Q9NQU5	PAK6	Q16539	MAPK14	S347	S351F	351	Missense	distal	4	no	11.402	9.827	EPSD	GDSC;CCLE	5.915	Down-regulation
CMGC_MAPK_p38_MAPK14_ST	Q9NQU5	PAK6	Q16539	MAPK14	S351	S351F	351	Missense	central	0	yes	8.820	0.000	EPSD	GDSC;CCLE	5.915	Loss
CMGC_MAPK_p38_MAPK14_ST	Q9NQU5	PAK6	Q16539	MAPK14	T354	S351F	351	Missense	distal	-3	no	6.255	3.548	EPSD	GDSC;CCLE	5.915	Loss
CMGC_MAPK_p38_MAPK14_ST	P00533	EGFR	Q16539	MAPK14	S227	N234D	234	Missense	distal	7	no	10.174	10.495	EPSD	GDSC;CCLE	5.915	Up-regulation
CMGC_MAPK_p38_MAPK14_ST	P00533	EGFR	Q16539	MAPK14	S752	A750E	750	Missense	proximal	-2	no	11.766	12.168	EPSD	GDSC	5.915	Up-regulation
CMGC_MAPK_p38_MAPK14_ST	P00533	EGFR	Q16539	MAPK14	S925	E928G	928	Missense	distal	3	no	6.152	6.198	EPSD	GDSC;CCLE	5.915	Up-regulation
CMGC_MAPK_p38_MAPK14_ST	P00533	EGFR	Q16539	MAPK14	S1153	W1157C	1157	Missense	distal	4	no	7.391	8.232	EPSD	GDSC;CCLE	5.915	Up-regulation
CMGC_MAPK_p38_MAPK14_ST	Q06413	MEF2C	Q16539	MAPK14	S98	D102E	102	Missense	distal	4	no	10.232	11.902	EPSD	GDSC	5.915	Up-regulation
CMGC_MAPK_p38_MAPK14_ST	Q06413	MEF2C	Q16539	MAPK14	S183	R189*	189	Missense	distal	6	no	8.120	7.710	EPSD	GDSC	5.915	Down-regulation
CMGC_MAPK_p38_MAPK14_ST	Q06413	MEF2C	Q16539	MAPK14	S222	R220*	220	Missense	proximal	-2	no	11.367	10.730	EPSD	GDSC	5.915	Down-regulation
CMGC_MAPK_p38_MAPK14_ST	Q06413	MEF2C	Q16539	MAPK14	S419	P420S	420	Missense	proximal	1	no	14.517	7.233	EPSD	GDSC;CCLE	5.915	Down-regulation
CMGC_MAPK_p38_MAPK14_ST	Q06413	MEF2C	Q16539	MAPK14	S429	S430W	430	Missense	proximal	1	no	5.005	6.319	EPSD	GDSC;CCLE	5.915	Gain
CMGC_MAPK_p38_MAPK14_ST	P42574	CASP3	Q16539	MAPK14	S150	G145W	145	Missense	distal	-5	no	7.178	7.761	PhosphoSitePlus	GDSC;CCLE	5.915	Up-regulation
CMGC_MAPK_p38_MAPK14_ST	P06702	S100A9	Q16539	MAPK14	T113	P107L	107	Missense	distal	-6	no	12.598	11.985	PhosphoSitePlus	GDSC;CCLE	5.915	Down-regulation
CMGC_MAPK_p38_MAPK14_ST	Q8NHW3	MAFA	Q16539	MAPK14	S325	S325G	325	Missense	central	0	yes	6.772	0.000	EPSD	GDSC	5.915	Loss
CMGC_MAPK_p38_MAPK14_ST	Q14934	NFATC4	Q16539	MAPK14	S237	S237N	237	Missense	central	0	yes	10.013	0.000	EPSD	GDSC	5.915	Loss
CMGC_MAPK_p38_MAPK14_ST	O43524	FOXO3	Q16539	MAPK14	S280	Q275*	275	Missense	distal	-5	no	4.974	6.193	EPSD	GDSC	5.915	Gain
CMGC_MAPK_p38_MAPK14_ST	O43524	FOXO3	Q16539	MAPK14	S325	V320I	320	Missense	distal	-5	no	12.190	11.986	EPSD	GDSC;CCLE	5.915	Down-regulation
CMGC_MAPK_p38_MAPK14_ST	O43524	FOXO3	Q16539	MAPK14	S402	M408V	408	Missense	distal	6	no	11.728	11.439	EPSD	GDSC;CCLE	5.915	Down-regulation
CMGC_MAPK_p38_MAPK14_ST	O43524	FOXO3	Q16539	MAPK14	S574	V576A	576	Missense	proximal	2	no	8.988	9.152	EPSD	GDSC;CCLE	5.915	Up-regulation
CMGC_MAPK_p38_MAPK14_ST	P42566	EPS15	Q16539	MAPK14	S563	G570R	570	Missense	distal	7	no	10.221	10.399	EPSD	GDSC;CCLE	5.915	Up-regulation
CMGC_MAPK_p38_MAPK14_ST	P42566	EPS15	Q16539	MAPK14	S796	K801N	801	Missense	distal	5	no	9.943	10.213	PhosphoSitePlus	GDSC	5.915	Up-regulation
CMGC_MAPK_p38_MAPK14_ST	P42566	EPS15	Q16539	MAPK14	S796	F800L	800	Missense	distal	4	no	9.943	10.439	PhosphoSitePlus	GDSC;CCLE	5.915	Up-regulation
CMGC_MAPK_p38_MAPK14_ST	P42566	EPS15	Q16539	MAPK14	S796	P797S	797	Missense	proximal	1	no	9.943	2.660	PhosphoSitePlus	GDSC;CCLE	5.915	Loss
CMGC_MAPK_p38_MAPK14_ST	P42566	EPS15	Q16539	MAPK14	S814	K816N	816	Missense	proximal	2	no	14.302	14.395	EPSD	GDSC;CCLE	5.915	Up-regulation
CMGC_MAPK_p38_MAPK14_ST	O60381	HBP1	Q16539	MAPK14	S135	V137A	137	Missense	proximal	2	no	10.736	10.900	EPSD	GDSC;CCLE	5.915	Up-regulation
CMGC_MAPK_p38_MAPK14_ST	O60381	HBP1	Q16539	MAPK14	S157	E162A	162	Missense	distal	5	no	8.293	7.693	EPSD	GDSC	5.915	Down-regulation
CMGC_MAPK_p38_MAPK14_ST	O60381	HBP1	Q16539	MAPK14	S406	N411S	411	Missense	distal	5	no	5.580	5.915	EPSD	GDSC;CCLE	5.915	Gain
CMGC_MAPK_p38_MAPK14_ST	Q8IW41	MAPKAPK5	Q16539	MAPK14	S212	P213Q	213	Missense	proximal	1	no	11.797	4.588	EPSD	GDSC;CCLE	5.915	Loss
CMGC_MAPK_p38_MAPK14_ST	Q8IW41	MAPKAPK5	Q16539	MAPK14	S212	P215S	215	Missense	distal	3	no	11.797	11.757	EPSD	GDSC;CCLE	5.915	Down-regulation
CMGC_MAPK_p38_MAPK14_ST	Q8IW41	MAPKAPK5	Q16539	MAPK14	T214	P213Q	213	Missense	proximal	-1	no	9.025	8.914	EPSD	GDSC;CCLE	5.915	Down-regulation
CMGC_MAPK_p38_MAPK14_ST	Q8IW41	MAPKAPK5	Q16539	MAPK14	T214	P215S	215	Missense	proximal	1	no	9.025	1.742	EPSD	GDSC;CCLE	5.915	Loss
CMGC_MAPK_p38_MAPK14_ST	Q8IW41	MAPKAPK5	Q16539	MAPK14	T217	P213Q	213	Missense	distal	-4	no	6.492	6.783	EPSD	GDSC;CCLE	5.915	Up-regulation
CMGC_MAPK_p38_MAPK14_ST	Q8IW41	MAPKAPK5	Q16539	MAPK14	T217	P215S	215	Missense	proximal	-2	no	6.492	6.003	EPSD	GDSC;CCLE	5.915	Down-regulation
CMGC_MAPK_p38_MAPK14_ST	P42677	RPS27	Q16539	MAPK14	S11	L7H	7	Missense	distal	-4	no	11.304	10.926	EPSD	GDSC;CCLE	5.915	Down-regulation
CMGC_MAPK_p38_MAPK14_ST	P42677	RPS27	Q16539	MAPK14	S11	E13D	13	Missense	proximal	2	no	11.304	10.853	EPSD	GDSC;CCLE	5.915	Down-regulation
CMGC_MAPK_p38_MAPK14_ST	P42677	RPS27	Q16539	MAPK14	S11	P10L	10	Missense	proximal	-1	no	11.304	11.489	EPSD	GDSC	5.915	Up-regulation
CMGC_MAPK_p38_MAPK14_ST	P42677	RPS27	Q16539	MAPK14	S27	S27I	27	Missense	central	0	yes	10.240	0.000	PhosphoSitePlus	GDSC;CCLE	5.915	Loss
CMGC_MAPK_p38_MAPK14_ST	P17302	GJA1	Q16539	MAPK14	S255	S262P	262	Missense	distal	7	no	9.570	9.348	EPSD	GDSC;CCLE	5.915	Down-regulation
CMGC_MAPK_p38_MAPK14_ST	P17302	GJA1	Q16539	MAPK14	S282	V289G	289	Missense	distal	7	no	13.285	13.228	EPSD;PhosphoSitePlus	GDSC;CCLE	5.915	Down-regulation
CMGC_MAPK_p38_MAPK14_ST	P17302	GJA1	Q16539	MAPK14	S314	A315G	315	Missense	proximal	1	no	6.095	4.618	EPSD	GDSC;CCLE	5.915	Loss
CMGC_MAPK_p38_MAPK14_ST	O43464	HTRA2	Q16539	MAPK14	T221	T221A	221	Missense	central	0	yes	6.807	0.000	EPSD	GDSC	5.915	Loss
CMGC_MAPK_p38_MAPK14_ST	P41235	HNF4A	Q16539	MAPK14	S313	R312H	312	Missense	proximal	-1	no	7.604	7.759	EPSD	GDSC;CCLE	5.915	Up-regulation
CMGC_MAPK_p38_MAPK14_ST	P41235	HNF4A	Q16539	MAPK14	S313	R310Q	310	Missense	distal	-3	no	7.604	5.824	EPSD	GDSC;CCLE	5.915	Loss
CMGC_MAPK_p38_MAPK14_ST	P41235	HNF4A	Q16539	MAPK14	S378	A385V	385	Missense	distal	7	no	11.760	11.651	EPSD	GDSC;CCLE	5.915	Down-regulation
CMGC_MAPK_p38_MAPK14_ST	P41235	HNF4A	Q16539	MAPK14	S378	P379H	379	Missense	proximal	1	no	11.760	-1.894	EPSD	GDSC;CCLE	5.915	Loss
CMGC_MAPK_p38_MAPK14_ST	P41235	HNF4A	Q16539	MAPK14	S461	I463V	463	Missense	proximal	2	no	6.182	6.233	EPSD	GDSC	5.915	Up-regulation
CMGC_MAPK_p38_MAPK14_ST	P41235	HNF4A	Q16539	MAPK14	S461	I463T	463	Missense	proximal	2	no	6.182	6.425	EPSD	GDSC	5.915	Up-regulation
CMGC_MAPK_p38_MAPK14_ST	P41235	HNF4A	Q16539	MAPK14	S461	P466L	466	Missense	distal	5	no	6.182	5.685	EPSD	GDSC;CCLE	5.915	Loss
CMGC_MAPK_p38_MAPK14_ST	P05787	KRT8	Q16539	MAPK14	S74	L76R	76	Missense	proximal	2	no	11.739	12.082	PhosphoSitePlus	GDSC;CCLE	5.915	Up-regulation
CMGC_MAPK_p38_MAPK14_ST	P05787	KRT8	Q16539	MAPK14	S451	T455A	455	Missense	distal	4	no	7.278	7.233	EPSD	GDSC	5.915	Down-regulation
CMGC_MAPK_p38_MAPK14_ST	P11362	FGFR1	Q16539	MAPK14	S785	E792K	792	Missense	distal	7	no	7.863	7.157	EPSD	GDSC;CCLE	5.915	Down-regulation
CMGC_MAPK_p38_MAPK14_ST	O95644	NFATC1	Q16539	MAPK14	S278	P275L	275	Missense	distal	-3	no	11.081	10.113	EPSD	GDSC	5.915	Down-regulation
CMGC_MAPK_p38_MAPK14_ST	O95644	NFATC1	Q16539	MAPK14	S282	P275L	275	Missense	distal	-7	no	12.738	12.544	EPSD	GDSC	5.915	Down-regulation
CMGC_MAPK_p38_MAPK14_ST	Q99626	CDX2	Q16539	MAPK14	S283	V285M	285	Missense	proximal	2	no	10.883	11.057	PhosphoSitePlus	GDSC;CCLE	5.915	Up-regulation
CMGC_MAPK_p38_MAPK14_ST	Q99626	CDX2	Q16539	MAPK14	S286	V285M	285	Missense	proximal	-1	no	8.061	7.968	EPSD	GDSC;CCLE	5.915	Down-regulation
CMGC_MAPK_p38_MAPK14_ST	Q15075	EEA1	Q16539	MAPK14	S354	E357D	357	Missense	distal	3	no	7.011	7.066	EPSD	GDSC;CCLE	5.915	Up-regulation
CMGC_MAPK_p38_MAPK14_ST	O75676	RPS6KA4	Q16539	MAPK14	S347	G346V	346	Missense	proximal	-1	no	13.505	13.507	EPSD	GDSC;CCLE	5.915	Up-regulation
CMGC_MAPK_p38_MAPK14_ST	O75676	RPS6KA4	Q16539	MAPK14	T542	D541E	541	Missense	proximal	-1	no	8.890	8.546	EPSD	GDSC;CCLE	5.915	Down-regulation
CMGC_MAPK_p38_MAPK14_ST	O75676	RPS6KA4	Q16539	MAPK14	T568	F571Y	571	Missense	distal	3	no	11.294	11.227	EPSD	GDSC	5.915	Down-regulation
CMGC_MAPK_p38_MAPK14_ST	O75676	RPS6KA4	Q16539	MAPK14	T739	S741Y	741	Missense	proximal	2	no	6.015	5.690	EPSD	GDSC;CCLE	5.915	Loss
CMGC_MAPK_p38_MAPK14_ST	O75676	RPS6KA4	Q16539	MAPK14	T739	R742C	742	Missense	distal	3	no	6.015	6.071	EPSD	GDSC;CCLE	5.915	Up-regulation
CMGC_MAPK_p38_MAPK14_ST	O75676	RPS6KA4	Q16539	MAPK14	T739	T739P	739	Missense	central	0	yes	6.015	0.000	EPSD	GDSC;CCLE	5.915	Loss
CMGC_MAPK_p38_MAPK14_ST	O75676	RPS6KA4	Q16539	MAPK14	S745	S741Y	741	Missense	distal	-4	no	12.491	12.487	EPSD	GDSC;CCLE	5.915	Down-regulation
CMGC_MAPK_p38_MAPK14_ST	O75676	RPS6KA4	Q16539	MAPK14	S745	R742C	742	Missense	distal	-3	no	12.491	10.295	EPSD	GDSC;CCLE	5.915	Down-regulation
CMGC_MAPK_p38_MAPK14_ST	O75676	RPS6KA4	Q16539	MAPK14	S745	T739P	739	Missense	distal	-6	no	12.491	12.157	EPSD	GDSC;CCLE	5.915	Down-regulation
CMGC_MAPK_p38_MAPK14_ST	P10275	AR	Q16539	MAPK14	S330	G334R	334	Missense	distal	4	no	6.855	6.370	EPSD	GDSC;CCLE	5.915	Down-regulation
CMGC_MAPK_p38_MAPK14_ST	P10275	AR	Q16539	MAPK14	S516	E523D	523	Missense	distal	7	no	10.977	10.782	EPSD	GDSC	5.915	Down-regulation
CMGC_MAPK_p38_MAPK14_ST	P06400	RB1	Q16539	MAPK14	S350	Q344*	344	Missense	distal	-6	no	7.284	6.046	EPSD	GDSC	5.915	Down-regulation
CMGC_MAPK_p38_MAPK14_ST	P06400	RB1	Q16539	MAPK14	S567	W563*	563	Missense	distal	-4	no	7.930	8.002	EPSD;PhosphoSitePlus	GDSC	5.915	Up-regulation
CMGC_MAPK_p38_MAPK14_ST	P06400	RB1	Q16539	MAPK14	S567	S567*	567	Missense	central	0	yes	7.930	0.000	EPSD;PhosphoSitePlus	GDSC	5.915	Loss
CMGC_MAPK_p38_MAPK14_ST	P06400	RB1	Q16539	MAPK14	S608	T601S	601	Missense	distal	-7	no	11.823	11.892	EPSD	GDSC;CCLE	5.915	Up-regulation
CMGC_MAPK_p38_MAPK14_ST	P06400	RB1	Q16539	MAPK14	T638	Q639*	639	Missense	proximal	1	no	3.076	5.990	EPSD	GDSC	5.915	Gain
CMGC_MAPK_p38_MAPK14_ST	P06400	RB1	Q16539	MAPK14	S780	R787*	787	Missense	distal	7	no	7.541	6.343	EPSD	GDSC	5.915	Down-regulation
CMGC_MAPK_p38_MAPK14_ST	P06400	RB1	Q16539	MAPK14	S788	R787*	787	Missense	proximal	-1	no	8.319	8.673	EPSD	GDSC	5.915	Up-regulation
CMGC_MAPK_p38_MAPK14_ST	P06400	RB1	Q16539	MAPK14	S795	G801*	801	Missense	distal	6	no	7.500	6.969	EPSD	GDSC	5.915	Down-regulation
CMGC_MAPK_p38_MAPK14_ST	P06400	RB1	Q16539	MAPK14	S807	G801*	801	Missense	distal	-6	no	12.132	10.599	EPSD	GDSC	5.915	Down-regulation
CMGC_MAPK_p38_MAPK14_ST	P06400	RB1	Q16539	MAPK14	T821	L819V	819	Missense	proximal	-2	no	8.094	8.396	EPSD	GDSC;CCLE	5.915	Up-regulation
CMGC_MAPK_p38_MAPK14_ST	P06400	RB1	Q16539	MAPK14	T826	L819V	819	Missense	distal	-7	no	10.042	9.618	EPSD	GDSC;CCLE	5.915	Down-regulation
CMGC_MAPK_p38_MAPK14_ST	P17181	IFNAR1	Q16539	MAPK14	S532	T531I	531	Missense	proximal	-1	no	7.024	6.886	PhosphoSitePlus	GDSC	5.915	Down-regulation
CMGC_MAPK_p38_MAPK14_ST	P40763	STAT3	Q16539	MAPK14	T440	E434K	434	Missense	distal	-6	no	6.042	5.627	EPSD	GDSC;CCLE	5.915	Loss
CMGC_MAPK_p38_MAPK14_ST	P40763	STAT3	Q16539	MAPK14	T714	C712Y	712	Missense	proximal	-2	no	8.540	9.678	EPSD	GDSC;CCLE	5.915	Up-regulation
CMGC_MAPK_p38_MAPK14_ST	O43684	BUB3	Q16539	MAPK14	S325	C327G	327	Missense	proximal	2	no	7.732	7.916	EPSD	GDSC;CCLE	5.915	Up-regulation
CMGC_MAPK_p38_MAPK14_ST	P10415	BCL2	Q16539	MAPK14	T56	P59T	59	Missense	distal	3	no	9.545	9.518	PhosphoSitePlus;EPSD	GDSC;CCLE	5.915	Down-regulation
CMGC_MAPK_p38_MAPK14_ST	P10415	BCL2	Q16539	MAPK14	T56	H55P	55	Missense	proximal	-1	no	9.545	9.590	PhosphoSitePlus;EPSD	GDSC;CCLE	5.915	Up-regulation
CMGC_MAPK_p38_MAPK14_ST	P30279	CCND2	Q16539	MAPK14	T280	A278T	278	Missense	proximal	-2	no	9.625	9.568	PhosphoSitePlus	GDSC;CCLE	5.915	Down-regulation
CMGC_MAPK_p38_MAPK14_ST	P55273	CDKN2D	Q16539	MAPK14	T141	P142S	142	Missense	proximal	1	no	10.969	3.685	EPSD	GDSC	5.915	Loss
CMGC_MAPK_p38_MAPK14_ST	P48436	SOX9	Q16539	MAPK14	S64	E65*	65	Missense	proximal	1	no	3.531	6.997	EPSD	GDSC	5.915	Gain
CMGC_MAPK_p38_MAPK14_ST	P48436	SOX9	Q16539	MAPK14	S211	H213Q	213	Missense	proximal	2	no	11.044	11.000	PhosphoSitePlus	GDSC;CCLE	5.915	Down-regulation
CMGC_MAPK_p38_MAPK14_ST	P48436	SOX9	Q16539	MAPK14	S214	H213Q	213	Missense	proximal	-1	no	7.938	7.871	EPSD	GDSC;CCLE	5.915	Down-regulation
CMGC_MAPK_p38_MAPK14_ST	P48436	SOX9	Q16539	MAPK14	S414	P415L	415	Missense	proximal	1	no	9.332	1.282	EPSD	GDSC;CCLE	5.915	Loss
CMGC_MAPK_p38_MAPK14_ST	P48436	SOX9	Q16539	MAPK14	S494	P501A	501	Missense	distal	7	no	8.400	8.644	EPSD	GDSC;CCLE	5.915	Up-regulation
CMGC_MAPK_p38_MAPK14_ST	Q07817	BCL2L1	Q16539	MAPK14	T47	S43L	43	Missense	distal	-4	no	5.682	6.281	EPSD	GDSC;CCLE	5.915	Gain
CMGC_MAPK_p38_MAPK14_ST	Q07817	BCL2L1	Q16539	MAPK14	S62	P55S	55	Missense	distal	-7	no	13.524	13.611	PhosphoSitePlus	GDSC;CCLE	5.915	Up-regulation
CMGC_MAPK_p38_MAPK14_ST	Q07817	BCL2L1	Q16539	MAPK14	S62	T69I	69	Missense	distal	7	no	13.524	13.112	PhosphoSitePlus	GDSC;CCLE	5.915	Down-regulation
CMGC_MAPK_p38_MAPK14_ST	Q07817	BCL2L1	Q16539	MAPK14	S62	G67V	67	Missense	distal	5	no	13.524	13.122	PhosphoSitePlus	GDSC;CCLE	5.915	Down-regulation
CMGC_MAPK_p38_MAPK14_ST	Q9H1K0	RBSN	Q16539	MAPK14	S211	T212P	212	Missense	proximal	1	no	3.240	10.694	EPSD	GDSC	5.915	Gain
CMGC_MAPK_p38_MAPK14_ST	Q9H1K0	RBSN	Q16539	MAPK14	S215	T214P	214	Missense	proximal	-1	no	13.118	13.094	PhosphoSitePlus	GDSC	5.915	Down-regulation
CMGC_MAPK_p38_MAPK14_ST	Q9H1K0	RBSN	Q16539	MAPK14	S215	T212P	212	Missense	distal	-3	no	13.118	12.672	PhosphoSitePlus	GDSC	5.915	Down-regulation
CMGC_MAPK_p38_MAPK14_ST	Q9H1K0	RBSN	Q16539	MAPK14	S219	T214P	214	Missense	distal	-5	no	9.704	9.711	EPSD	GDSC	5.915	Up-regulation
CMGC_MAPK_p38_MAPK14_ST	Q9H1K0	RBSN	Q16539	MAPK14	S219	T212P	212	Missense	distal	-7	no	9.704	9.687	EPSD	GDSC	5.915	Down-regulation
CMGC_MAPK_p38_MAPK14_ST	Q9H1K0	RBSN	Q16539	MAPK14	S541	R545Q	545	Missense	distal	4	no	6.676	6.472	EPSD	GDSC	5.915	Down-regulation
CMGC_MAPK_p38_MAPK14_ST	Q9H1K0	RBSN	Q16539	MAPK14	S578	S582N	582	Missense	distal	4	no	11.616	11.099	EPSD	GDSC	5.915	Down-regulation
CMGC_MAPK_p38_MAPK14_ST	Q9H1K0	RBSN	Q16539	MAPK14	T588	S582N	582	Missense	distal	-6	no	13.707	13.284	EPSD	GDSC	5.915	Down-regulation
CMGC_MAPK_p38_MAPK14_ST	Q02156	PRKCE	Q16539	MAPK14	T228	D230V	230	Missense	proximal	2	no	9.657	9.715	EPSD	GDSC;CCLE	5.915	Up-regulation
CMGC_MAPK_p38_MAPK14_ST	Q02156	PRKCE	Q16539	MAPK14	S329	P330L	330	Missense	proximal	1	no	8.746	0.696	EPSD	GDSC;CCLE	5.915	Loss
CMGC_MAPK_p38_MAPK14_ST	Q02156	PRKCE	Q16539	MAPK14	S336	P330L	330	Missense	distal	-6	no	6.358	5.745	EPSD	GDSC;CCLE	5.915	Loss
CMGC_MAPK_p38_MAPK14_ST	Q02156	PRKCE	Q16539	MAPK14	S337	P330L	330	Missense	distal	-7	no	12.983	12.790	EPSD	GDSC;CCLE	5.915	Down-regulation
CMGC_MAPK_p38_MAPK14_ST	Q02156	PRKCE	Q16539	MAPK14	S380	R377Q	377	Missense	distal	-3	no	6.788	5.009	EPSD	GDSC	5.915	Loss
CMGC_MAPK_p38_MAPK14_ST	Q02156	PRKCE	Q16539	MAPK14	S381	R377Q	377	Missense	distal	-4	no	12.483	12.852	EPSD	GDSC	5.915	Up-regulation
CMGC_MAPK_p38_MAPK14_ST	P23769	GATA2	Q16539	MAPK14	T303	G310S	310	Missense	distal	7	no	9.980	10.123	EPSD	GDSC	5.915	Up-regulation
CMGC_MAPK_p38_MAPK14_ST	P02511	CRYAB	Q16539	MAPK14	S19	R22H	22	Missense	distal	3	no	10.811	10.882	EPSD	GDSC;CCLE	5.915	Up-regulation
CMGC_MAPK_p38_MAPK14_ST	P02511	CRYAB	Q16539	MAPK14	S45	P51L	51	Missense	distal	6	no	10.021	9.882	EPSD	GDSC	5.915	Down-regulation
CMGC_MAPK_p38_MAPK14_ST	P02511	CRYAB	Q16539	MAPK14	S45	T40M	40	Missense	distal	-5	no	10.021	9.732	EPSD	GDSC;CCLE	5.915	Down-regulation
CMGC_MAPK_p38_MAPK14_ST	P02511	CRYAB	Q16539	MAPK14	S85	F84L	84	Missense	proximal	-1	no	9.324	9.360	EPSD	GDSC;CCLE	5.915	Up-regulation
CMGC_MAPK_p38_MAPK14_ST	Q15910	EZH2	Q16539	MAPK14	S75	T80P	80	Missense	distal	5	no	7.697	7.413	EPSD	GDSC;CCLE	5.915	Down-regulation
CMGC_MAPK_p38_MAPK14_ST	Q15910	EZH2	Q16539	MAPK14	T261	N268D	268	Missense	distal	7	no	9.676	9.997	EPSD	GDSC;CCLE	5.915	Up-regulation
CMGC_MAPK_p38_MAPK14_ST	P56817	BACE1	Q16539	MAPK14	S59	P54T	54	Missense	distal	-5	no	6.121	6.114	EPSD	GDSC	5.915	Down-regulation
CMGC_MAPK_p38_MAPK14_ST	P56817	BACE1	Q16539	MAPK14	T252	Y245H	245	Missense	distal	-7	no	10.102	10.199	EPSD	GDSC;CCLE	5.915	Up-regulation
CMGC_MAPK_p38_MAPK14_ST	O15198	SMAD9	Q16539	MAPK14	T136	H130N	130	Missense	distal	-6	no	10.665	11.311	PhosphoSitePlus	GDSC;CCLE	5.915	Up-regulation
CMGC_MAPK_p38_MAPK14_ST	Q92945	KHSRP	Q16539	MAPK14	T143	P140T	140	Missense	distal	-3	no	6.478	6.924	EPSD	GDSC	5.915	Up-regulation
CMGC_MAPK_p38_MAPK14_ST	Q92945	KHSRP	Q16539	MAPK14	T143	E148*	148	Missense	distal	5	no	6.478	4.330	EPSD	GDSC	5.915	Loss
CMGC_MAPK_p38_MAPK14_ST	Q92945	KHSRP	Q16539	MAPK14	S480	I476T	476	Missense	distal	-4	no	9.381	9.491	EPSD	GDSC;CCLE	5.915	Up-regulation
CMGC_MAPK_p38_MAPK14_ST	Q92945	KHSRP	Q16539	MAPK14	T692	A686S	686	Missense	distal	-6	no	12.764	13.307	PhosphoSitePlus	GDSC	5.915	Up-regulation
CMGC_MAPK_p38_MAPK14_ST	P05198	EIF2S1	Q16539	MAPK14	S52	R54W	54	Missense	proximal	2	no	7.729	7.231	PhosphoSitePlus	GDSC;CCLE	5.915	Down-regulation
CMGC_MAPK_p38_MAPK14_ST	Q13309	SKP2	Q16539	MAPK14	S179	L174F	174	Missense	distal	-5	no	7.705	7.761	EPSD	GDSC;CCLE	5.915	Up-regulation
CMGC_MAPK_p38_MAPK14_ST	Q13309	SKP2	Q16539	MAPK14	S179	A175S	175	Missense	distal	-4	no	7.705	7.665	EPSD	GDSC;CCLE	5.915	Down-regulation
CMGC_MAPK_p38_MAPK14_ST	Q9H3M7	TXNIP	Q16539	MAPK14	T306	G301D	301	Missense	distal	-5	no	6.507	6.749	EPSD	GDSC;CCLE	5.915	Up-regulation
CMGC_MAPK_p38_MAPK14_ST	Q9H3M7	TXNIP	Q16539	MAPK14	S307	G301D	301	Missense	distal	-6	no	8.311	8.042	EPSD	GDSC;CCLE	5.915	Down-regulation
CMGC_MAPK_p38_MAPK14_ST	Q9H3M7	TXNIP	Q16539	MAPK14	S361	D360N	360	Missense	proximal	-1	no	10.642	10.457	PhosphoSitePlus	GDSC	5.915	Down-regulation
CMGC_MAPK_p38_MAPK14_ST	P18850	ATF6	Q16539	MAPK14	S13	M11T	11	Missense	proximal	-2	no	10.641	10.733	EPSD	GDSC;CCLE	5.915	Up-regulation
CMGC_MAPK_p38_MAPK14_ST	P18850	ATF6	Q16539	MAPK14	S16	M11T	11	Missense	distal	-5	no	10.902	11.190	EPSD	GDSC;CCLE	5.915	Up-regulation
CMGC_MAPK_p38_MAPK14_ST	P18850	ATF6	Q16539	MAPK14	S94	E89D	89	Missense	distal	-5	no	12.383	13.257	EPSD	GDSC	5.915	Up-regulation
CMGC_MAPK_p38_MAPK14_ST	P18850	ATF6	Q16539	MAPK14	S104	D109G	109	Missense	distal	5	no	10.523	10.812	EPSD	GDSC	5.915	Up-regulation
CMGC_MAPK_p38_MAPK14_ST	P18850	ATF6	Q16539	MAPK14	S373	K370*	370	Missense	distal	-3	no	10.127	9.086	EPSD	GDSC	5.915	Down-regulation
Other_NAK_BIKE_AAK1_ST	P49757	NUMB	Q2M2I8	AAK1	T243	S240C	240	Missense	distal	-3	no	2.906	2.799	EPSD	GDSC;CCLE	2.491	Down-regulation
Other_NAK_BIKE_AAK1_ST	P49757	NUMB	Q2M2I8	AAK1	T246	S240C	240	Missense	distal	-6	no	2.702	2.920	EPSD	GDSC;CCLE	2.491	Up-regulation
Other_NAK_BIKE_AAK1_ST	P49757	NUMB	Q2M2I8	AAK1	S284	F280L	280	Missense	distal	-4	no	3.653	3.514	EPSD	GDSC;CCLE	2.491	Down-regulation
Other_NAK_BIKE_AAK1_ST	Q96CW1	AP2M1	Q2M2I8	AAK1	T134	G127V	127	Missense	distal	-7	no	2.496	2.469	EPSD	GDSC	2.491	Loss
Other_NAK_BIKE_AAK1_ST	Q96CW1	AP2M1	Q2M2I8	AAK1	T134	G127D	127	Missense	distal	-7	no	2.496	2.541	EPSD	GDSC;CCLE	2.491	Up-regulation
Other_NAK_BIKE_AAK1_ST	Q96CW1	AP2M1	Q2M2I8	AAK1	T247	R253*	253	Missense	distal	6	no	2.562	2.579	EPSD	GDSC	2.491	Up-regulation
TK_Fer_FES_Y	P07332	FES	P07332	FES	Y261	Q267*	267	Missense	distal	6	no	8.730	9.380	EPSD	GDSC	7.476	Up-regulation
TK_Fer_FES_Y	P11274	BCR	P07332	FES	Y177	F176L	176	Missense	proximal	-1	no	15.215	14.999	EPSD	GDSC;CCLE	7.476	Down-regulation
TK_Fer_FES_Y	P11274	BCR	P07332	FES	Y276	Y279H	279	Missense	distal	3	no	14.785	14.484	EPSD	GDSC;CCLE	7.476	Down-regulation
TK_Fer_FES_Y	P11274	BCR	P07332	FES	Y279	Y279H	279	Missense	central	0	yes	16.933	0.000	EPSD	GDSC;CCLE	7.476	Loss
TK_Fer_FES_Y	P11274	BCR	P07332	FES	Y283	Y279H	279	Missense	distal	-4	no	15.668	15.696	EPSD	GDSC;CCLE	7.476	Up-regulation
Other_WNK_WNK4_ST	Q96J92	WNK4	Q96J92	WNK4	S102	E107V	107	Missense	distal	5	no	3.100	3.512	EPSD	GDSC;CCLE	2.324	Up-regulation
Other_WNK_WNK4_ST	Q96J92	WNK4	Q96J92	WNK4	S102	P105T	105	Missense	distal	3	no	3.100	2.964	EPSD	GDSC;CCLE	2.324	Down-regulation
Other_WNK_WNK4_ST	Q96J92	WNK4	Q96J92	WNK4	S102	E107D	107	Missense	distal	5	no	3.100	3.309	EPSD	GDSC;CCLE	2.324	Up-regulation
Other_WNK_WNK4_ST	Q96J92	WNK4	Q96J92	WNK4	S335	S331F	331	Missense	distal	-4	no	3.011	3.041	PhosphoSitePlus	GDSC;CCLE	2.324	Up-regulation
Other_WNK_WNK4_ST	Q96J92	WNK4	Q96J92	WNK4	S728	E723K	723	Missense	distal	-5	no	2.997	2.882	EPSD	GDSC	2.324	Down-regulation
Other_WNK_WNK4_ST	P55017	SLC12A3	Q96J92	WNK4	S17	A13T	13	Missense	distal	-4	no	3.236	3.569	EPSD	GDSC;CCLE	2.324	Up-regulation
Other_WNK_WNK4_ST	P55017	SLC12A3	Q96J92	WNK4	S17	D12Y	12	Missense	distal	-5	no	3.236	3.245	EPSD	GDSC	2.324	Up-regulation
Other_WNK_WNK4_ST	P55017	SLC12A3	Q96J92	WNK4	S17	A13P	13	Missense	distal	-4	no	3.236	3.360	EPSD	GDSC	2.324	Up-regulation
Other_WNK_WNK4_ST	P55017	SLC12A3	Q96J92	WNK4	T50	R54H	54	Missense	distal	4	no	4.925	5.005	PhosphoSitePlus;EPSD	GDSC;CCLE	2.324	Up-regulation
Other_IKK_CHUK_ST	Q9Y6Q9	NCOA3	O15111	CHUK	S101	Q96R	96	Missense	distal	-5	no	189.644	185.009	EPSD	GDSC;CCLE	187.474	Loss
Other_IKK_CHUK_ST	Q9Y6Q9	NCOA3	O15111	CHUK	S640	P641S	641	Missense	proximal	1	no	275.702	270.301	EPSD	GDSC;CCLE	187.474	Down-regulation
Other_IKK_CHUK_ST	Q9Y6Q9	NCOA3	O15111	CHUK	S644	P641S	641	Missense	distal	-3	no	208.303	194.435	EPSD	GDSC;CCLE	187.474	Down-regulation
Other_IKK_CHUK_ST	Q9Y6Q9	NCOA3	O15111	CHUK	S652	S657F	657	Missense	distal	5	no	183.066	189.892	EPSD	GDSC;CCLE	187.474	Gain
Other_IKK_CHUK_ST	Q9Y6Q9	NCOA3	O15111	CHUK	S662	S657F	657	Missense	distal	-5	no	215.810	196.624	EPSD	GDSC;CCLE	187.474	Down-regulation
Other_IKK_CHUK_ST	Q9Y6Q9	NCOA3	O15111	CHUK	S715	V721I	721	Missense	distal	6	no	202.517	196.821	EPSD	GDSC	187.474	Down-regulation
Other_IKK_CHUK_ST	Q9Y6Q9	NCOA3	O15111	CHUK	S857	Y852C	852	Missense	distal	-5	no	229.164	218.745	PhosphoSitePlus	GDSC;CCLE	187.474	Down-regulation
Other_IKK_CHUK_ST	Q9Y6Q9	NCOA3	O15111	CHUK	S916	S917L	917	Missense	proximal	1	no	194.919	214.394	EPSD	GDSC	187.474	Up-regulation
Other_IKK_CHUK_ST	Q99558	MAP3K14	O15111	CHUK	S410	Q403H	403	Missense	distal	-7	no	193.756	191.742	EPSD	GDSC	187.474	Down-regulation
Other_IKK_CHUK_ST	P03372	ESR1	O15111	CHUK	S167	G160S	160	Missense	distal	-7	no	203.246	204.284	EPSD	GDSC	187.474	Up-regulation
Other_IKK_CHUK_ST	P03372	ESR1	O15111	CHUK	S167	R164I	164	Missense	distal	-3	no	203.246	191.429	EPSD	GDSC;CCLE	187.474	Down-regulation
Other_IKK_CHUK_ST	Q00653	NFKB2	O15111	CHUK	S239	R241Q	241	Missense	proximal	2	no	243.078	240.410	EPSD	GDSC;CCLE	187.474	Down-regulation
Other_IKK_CHUK_ST	Q00653	NFKB2	O15111	CHUK	S717	D714N	714	Missense	distal	-3	no	199.018	197.369	EPSD	GDSC	187.474	Down-regulation
Other_IKK_CHUK_ST	Q01201	RELB	O15111	CHUK	S41	S42L	42	Missense	proximal	1	no	180.932	200.406	EPSD	GDSC;CCLE	187.474	Gain
Other_IKK_CHUK_ST	Q01201	RELB	O15111	CHUK	S42	S42L	42	Missense	central	0	yes	204.700	0.000	EPSD	GDSC;CCLE	187.474	Loss
Other_IKK_CHUK_ST	Q01201	RELB	O15111	CHUK	S48	S42L	42	Missense	distal	-6	no	188.722	187.218	EPSD	GDSC;CCLE	187.474	Loss
Other_IKK_CHUK_ST	Q01201	RELB	O15111	CHUK	S151	S156R	156	Missense	distal	5	no	254.845	258.627	EPSD	GDSC;CCLE	187.474	Up-regulation
Other_IKK_CHUK_ST	Q01201	RELB	O15111	CHUK	S254	S254P	254	Missense	central	0	yes	214.747	0.000	EPSD	GDSC;CCLE	187.474	Loss
Other_IKK_CHUK_ST	Q01201	RELB	O15111	CHUK	S472	S472Y	472	Missense	central	0	yes	230.199	0.000	PhosphoSitePlus	GDSC;CCLE	187.474	Loss
Other_IKK_CHUK_ST	Q01201	RELB	O15111	CHUK	S573	S573F	573	Missense	central	0	yes	224.036	0.000	EPSD	GDSC;CCLE	187.474	Loss
Other_IKK_CHUK_ST	P35222	CTNNB1	O15111	CHUK	S179	H176Y	176	Missense	distal	-3	no	210.016	209.614	EPSD	GDSC;CCLE	187.474	Down-regulation
Other_IKK_CHUK_ST	Q92793	CREBBP	O15111	CHUK	S306	L307F	307	Missense	proximal	1	no	206.435	197.457	EPSD	GDSC;CCLE	187.474	Down-regulation
Other_IKK_CHUK_ST	Q92793	CREBBP	O15111	CHUK	S381	G375*	375	Missense	distal	-6	no	194.254	202.368	EPSD	GDSC	187.474	Up-regulation
Other_IKK_CHUK_ST	Q92793	CREBBP	O15111	CHUK	S381	M388I	388	Missense	distal	7	no	194.254	190.516	EPSD	GDSC;CCLE	187.474	Down-regulation
Other_IKK_CHUK_ST	Q92793	CREBBP	O15111	CHUK	S1043	I1038V	1038	Missense	distal	-5	no	184.096	189.002	EPSD	GDSC;CCLE	187.474	Gain
Other_IKK_CHUK_ST	Q92793	CREBBP	O15111	CHUK	S1609	N1615S	1615	Missense	distal	6	no	199.900	196.430	EPSD	GDSC;CCLE	187.474	Down-regulation
Other_IKK_CHUK_ST	P42345	MTOR	O15111	CHUK	S831	M825I	825	Missense	distal	-6	no	189.489	188.335	EPSD	GDSC;CCLE	187.474	Down-regulation
Other_IKK_CHUK_ST	P42345	MTOR	O15111	CHUK	S1415	P1408S	1408	Missense	distal	-7	no	232.439	235.973	PhosphoSitePlus	GDSC;CCLE	187.474	Up-regulation
Other_IKK_CHUK_ST	Q04206	RELA	O15111	CHUK	T136	N139T	139	Missense	distal	3	no	192.720	186.164	EPSD	GDSC	187.474	Loss
Other_IKK_CHUK_ST	Q04206	RELA	O15111	CHUK	S238	D243Y	243	Missense	distal	5	no	190.680	191.249	EPSD	GDSC;CCLE	187.474	Up-regulation
Other_IKK_CHUK_ST	Q86VP1	TAX1BP1	O15111	CHUK	T145	G148D	148	Missense	distal	3	no	173.458	201.197	EPSD	GDSC	187.474	Gain
Other_IKK_CHUK_ST	Q86VP1	TAX1BP1	O15111	CHUK	S254	K248N	248	Missense	distal	-6	no	237.788	236.694	EPSD	GDSC;CCLE	187.474	Down-regulation
Other_IKK_CHUK_ST	Q86VP1	TAX1BP1	O15111	CHUK	S345	D348N	348	Missense	distal	3	no	228.914	191.953	EPSD	GDSC;CCLE	187.474	Down-regulation
Other_IKK_CHUK_ST	Q86VP1	TAX1BP1	O15111	CHUK	S683	L688S	688	Missense	distal	5	no	203.413	200.824	EPSD	GDSC;CCLE	187.474	Down-regulation
Other_IKK_CHUK_ST	Q86VP1	TAX1BP1	O15111	CHUK	S691	L688S	688	Missense	distal	-3	no	206.607	202.843	EPSD	GDSC;CCLE	187.474	Down-regulation
Other_IKK_CHUK_ST	Q15717	ELAVL1	O15111	CHUK	S242	I246T	246	Missense	distal	4	no	195.762	192.414	EPSD	GDSC;CCLE	187.474	Down-regulation
Other_IKK_CHUK_ST	Q15717	ELAVL1	O15111	CHUK	S304	A299T	299	Missense	distal	-5	no	229.646	239.226	PhosphoSitePlus	GDSC;CCLE	187.474	Up-regulation
Other_IKK_CHUK_ST	P24385	CCND1	O15111	CHUK	S197	P200L	200	Missense	distal	3	no	194.072	189.726	EPSD	GDSC;CCLE	187.474	Down-regulation
Other_IKK_CHUK_ST	O43524	FOXO3	O15111	CHUK	S253	R249W	249	Missense	distal	-4	no	196.328	181.878	EPSD	GDSC;CCLE	187.474	Loss
Other_IKK_CHUK_ST	O43524	FOXO3	O15111	CHUK	S330	E335G	335	Missense	distal	5	no	198.782	194.394	EPSD	GDSC;CCLE	187.474	Down-regulation
Other_IKK_CHUK_ST	O43524	FOXO3	O15111	CHUK	S644	D643H	643	Missense	proximal	-1	no	217.602	215.053	PhosphoSitePlus	GDSC	187.474	Down-regulation
Other_IKK_CHUK_ST	Q04864	REL	O15111	CHUK	S526	V527A	527	Missense	proximal	1	no	236.654	221.425	EPSD	GDSC;CCLE	187.474	Down-regulation
Other_IKK_CHUK_ST	Q04864	REL	O15111	CHUK	S557	T553I	553	Missense	distal	-4	no	248.915	247.848	PhosphoSitePlus	GDSC;CCLE	187.474	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	Q99638	RAD9A	P24941	CDK2	S277	S277F	277	Missense	central	0	yes	17.034	0.000	EPSD	GDSC;CCLE	8.148	Loss
CMGC_CDK_CDK2_CDK2_ST	Q99638	RAD9A	P24941	CDK2	T292	P285R	285	Missense	distal	-7	no	12.997	13.340	EPSD	GDSC;CCLE	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	Q99638	RAD9A	P24941	CDK2	S336	P339S	339	Missense	distal	3	no	14.003	14.037	EPSD	GDSC;CCLE	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	Q99638	RAD9A	P24941	CDK2	S336	P339L	339	Missense	distal	3	no	14.003	13.619	EPSD	GDSC;CCLE	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	Q99638	RAD9A	P24941	CDK2	T355	P357Q	357	Missense	proximal	2	no	14.044	14.103	EPSD	GDSC;CCLE	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	Q99638	RAD9A	P24941	CDK2	T355	S350G	350	Missense	distal	-5	no	14.044	14.168	EPSD	GDSC;CCLE	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	Q99638	RAD9A	P24941	CDK2	S375	R374C	374	Missense	proximal	-1	no	14.914	14.217	EPSD	GDSC;CCLE	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	Q99638	RAD9A	P24941	CDK2	S375	P376H	376	Missense	proximal	1	no	14.914	8.156	EPSD	GDSC;CCLE	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	Q99638	RAD9A	P24941	CDK2	S375	P379L	379	Missense	distal	4	no	14.914	15.026	EPSD	GDSC;CCLE	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	Q99638	RAD9A	P24941	CDK2	S375	I369F	369	Missense	distal	-6	no	14.914	14.916	EPSD	GDSC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	Q99638	RAD9A	P24941	CDK2	S380	R374C	374	Missense	distal	-6	no	13.307	13.310	EPSD	GDSC;CCLE	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	Q99638	RAD9A	P24941	CDK2	S380	P376H	376	Missense	distal	-4	no	13.307	12.703	EPSD	GDSC;CCLE	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	Q99638	RAD9A	P24941	CDK2	S380	P379L	379	Missense	proximal	-1	no	13.307	13.127	EPSD	GDSC;CCLE	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	Q8IZL8	PELP1	P24941	CDK2	T807	P808S	808	Missense	proximal	1	no	10.151	-1.115	EPSD	GDSC	8.148	Loss
CMGC_CDK_CDK2_CDK2_ST	Q8IZL8	PELP1	P24941	CDK2	T1092	E1095K	1095	Missense	distal	3	no	7.510	9.595	EPSD	GDSC	8.148	Gain
CMGC_CDK_CDK2_CDK2_ST	Q07820	MCL1	P24941	CDK2	S121	M120V	120	Missense	proximal	-1	no	15.691	14.598	EPSD;PhosphoSitePlus	GDSC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	Q08999	RBL2	P24941	CDK2	T417	T423M	423	Missense	distal	6	no	14.105	14.078	EPSD;PhosphoSitePlus	GDSC;CCLE	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	Q08999	RBL2	P24941	CDK2	S995	S995G	995	Missense	central	0	yes	9.084	0.000	EPSD	GDSC	8.148	Loss
CMGC_CDK_CDK2_CDK2_ST	Q08999	RBL2	P24941	CDK2	S1035	M1029I	1029	Missense	distal	-6	no	12.670	12.665	EPSD	GDSC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	Q08999	RBL2	P24941	CDK2	S1068	R1070*	1070	Missense	proximal	2	no	14.605	14.619	EPSD;PhosphoSitePlus	GDSC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	Q08999	RBL2	P24941	CDK2	S1080	Y1076*	1076	Missense	distal	-4	no	17.587	16.388	EPSD;PhosphoSitePlus	GDSC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	Q08999	RBL2	P24941	CDK2	S1112	P1119A	1119	Missense	distal	7	no	17.304	17.689	EPSD;PhosphoSitePlus	GDSC;CCLE	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	P10636	MAPT	P24941	CDK2	S46	Q49H	49	Missense	distal	3	no	15.504	16.551	EPSD	GDSC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	P10636	MAPT	P24941	CDK2	S46	A41V	41	Missense	distal	-5	no	15.504	15.510	EPSD	GDSC;CCLE	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	P10636	MAPT	P24941	CDK2	T50	Q49H	49	Missense	proximal	-1	no	13.521	13.948	EPSD	GDSC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	P10636	MAPT	P24941	CDK2	T173	D177V	177	Missense	distal	4	no	9.577	9.869	EPSD	GDSC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	P10636	MAPT	P24941	CDK2	S228	R222H	222	Missense	distal	-6	no	9.983	9.985	EPSD	GDSC;CCLE	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	P10636	MAPT	P24941	CDK2	T470	A475V	475	Missense	distal	5	no	10.897	10.854	EPSD	GDSC;CCLE	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	P10636	MAPT	P24941	CDK2	S739	S739C	739	Missense	central	0	yes	16.401	0.000	EPSD	GDSC	8.148	Loss
CMGC_CDK_CDK2_CDK2_ST	Q99728	BARD1	P24941	CDK2	S148	V154F	154	Missense	distal	6	no	13.307	13.291	EPSD;PhosphoSitePlus	GDSC;CCLE	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	Q99728	BARD1	P24941	CDK2	S184	Q177*	177	Missense	distal	-7	no	12.220	12.738	EPSD	GDSC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	Q99728	BARD1	P24941	CDK2	S184	S179L	179	Missense	distal	-5	no	12.220	12.276	EPSD	GDSC;CCLE	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	Q99728	BARD1	P24941	CDK2	S186	S179L	179	Missense	distal	-7	no	9.780	9.965	EPSD	GDSC;CCLE	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	Q99728	BARD1	P24941	CDK2	S288	K292E	292	Missense	distal	4	no	14.800	14.415	EPSD;PhosphoSitePlus	GDSC;CCLE	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	Q99728	BARD1	P24941	CDK2	T299	P300L	300	Missense	proximal	1	no	16.297	6.476	EPSD;PhosphoSitePlus	GDSC;CCLE	8.148	Loss
CMGC_CDK_CDK2_CDK2_ST	Q99728	BARD1	P24941	CDK2	T299	K292E	292	Missense	distal	-7	no	16.297	16.434	EPSD;PhosphoSitePlus	GDSC;CCLE	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	Q99728	BARD1	P24941	CDK2	S410	R405M	405	Missense	distal	-5	no	9.833	9.893	EPSD	GDSC;CCLE	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	O43303	CCP110	P24941	CDK2	S372	R377*	377	Missense	distal	5	no	15.180	15.270	EPSD;PhosphoSitePlus	GDSC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	O43303	CCP110	P24941	CDK2	S400	E405*	405	Missense	distal	5	no	12.307	12.424	EPSD;PhosphoSitePlus	GDSC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	Q15648	MED1	P24941	CDK2	T212	H205Y	205	Missense	distal	-7	no	12.211	12.214	EPSD	GDSC;CCLE	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	Q15648	MED1	P24941	CDK2	T212	Y210C	210	Missense	proximal	-2	no	12.211	11.714	EPSD	GDSC;CCLE	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	Q15648	MED1	P24941	CDK2	S558	G559S	559	Missense	proximal	1	no	8.350	4.396	EPSD	GDSC;CCLE	8.148	Loss
CMGC_CDK_CDK2_CDK2_ST	Q15648	MED1	P24941	CDK2	T562	G559S	559	Missense	distal	-3	no	13.317	13.308	EPSD	GDSC;CCLE	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	Q15648	MED1	P24941	CDK2	T562	F567L	567	Missense	distal	5	no	13.317	13.139	EPSD	GDSC;CCLE	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	Q15648	MED1	P24941	CDK2	S675	G674S	674	Missense	proximal	-1	no	14.437	12.918	EPSD	GDSC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	Q15648	MED1	P24941	CDK2	S675	M678I	678	Missense	distal	3	no	14.437	14.009	EPSD	GDSC;CCLE	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	Q15648	MED1	P24941	CDK2	S675	I680M	680	Missense	distal	5	no	14.437	14.652	EPSD	GDSC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	Q15648	MED1	P24941	CDK2	S848	A845T	845	Missense	distal	-3	no	16.825	16.844	EPSD	GDSC;CCLE	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	Q15648	MED1	P24941	CDK2	S848	S851G	851	Missense	distal	3	no	16.825	16.690	EPSD	GDSC;CCLE	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	Q15648	MED1	P24941	CDK2	S853	N856D	856	Missense	distal	3	no	13.040	11.788	EPSD	GDSC;CCLE	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	Q15648	MED1	P24941	CDK2	S853	S851G	851	Missense	proximal	-2	no	13.040	12.948	EPSD	GDSC;CCLE	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	Q15648	MED1	P24941	CDK2	S1223	I1225F	1225	Missense	proximal	2	no	14.926	15.199	EPSD	GDSC;CCLE	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	Q15648	MED1	P24941	CDK2	S1229	I1225F	1225	Missense	distal	-4	no	8.322	7.865	EPSD	GDSC;CCLE	8.148	Loss
CMGC_CDK_CDK2_CDK2_ST	Q15648	MED1	P24941	CDK2	S1379	S1375F	1375	Missense	distal	-4	no	9.203	8.241	EPSD	GDSC;CCLE	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	Q15648	MED1	P24941	CDK2	S1401	S1403T	1403	Missense	proximal	2	no	12.838	12.594	EPSD	GDSC;CCLE	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	Q15648	MED1	P24941	CDK2	S1536	D1541E	1541	Missense	distal	5	no	14.103	14.008	EPSD	GDSC;CCLE	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	P62324	BTG1	P24941	CDK2	S159	K162R	162	Missense	distal	3	no	16.830	15.841	PhosphoSitePlus	GDSC;CCLE	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	P19338	NCL	P24941	CDK2	T113	G115D	115	Missense	proximal	2	no	14.880	14.759	EPSD	GDSC;CCLE	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	P19338	NCL	P24941	CDK2	T121	G115D	115	Missense	distal	-6	no	15.552	15.548	PhosphoSitePlus;EPSD	GDSC;CCLE	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	P19338	NCL	P24941	CDK2	T214	E207K	207	Missense	distal	-7	no	15.166	15.029	EPSD	GDSC;CCLE	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	P19338	NCL	P24941	CDK2	T214	E209A	209	Missense	distal	-5	no	15.166	15.154	EPSD	GDSC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	P19338	NCL	P24941	CDK2	S563	R567I	567	Missense	distal	4	no	14.240	14.331	EPSD	GDSC;CCLE	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	P19338	NCL	P24941	CDK2	T606	S609F	609	Missense	distal	3	no	8.433	8.358	EPSD	GDSC;CCLE	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	P19338	NCL	P24941	CDK2	T606	S608F	608	Missense	proximal	2	no	8.433	8.618	EPSD	GDSC;CCLE	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	P13639	EEF2	P24941	CDK2	S325	L323P	323	Missense	proximal	-2	no	9.540	9.764	EPSD	GDSC;CCLE	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	P13639	EEF2	P24941	CDK2	S502	R495Q	495	Missense	distal	-7	no	16.016	15.630	EPSD	GDSC;CCLE	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	Q9NYV6	RRN3	P24941	CDK2	S44	F41I	41	Missense	distal	-3	no	15.360	15.193	PhosphoSitePlus	GDSC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	Q9NYV6	RRN3	P24941	CDK2	T200	W202L	202	Missense	proximal	2	no	13.090	12.728	EPSD	GDSC;CCLE	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	Q9NYV6	RRN3	P24941	CDK2	T623	P624Q	624	Missense	proximal	1	no	14.114	6.202	EPSD	GDSC;CCLE	8.148	Loss
CMGC_CDK_CDK2_CDK2_ST	Q9H211	CDT1	P24941	CDK2	S79	A85S	85	Missense	distal	6	no	12.445	12.450	EPSD	GDSC;CCLE	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	Q9H211	CDT1	P24941	CDK2	S79	T82P	82	Missense	distal	3	no	12.445	12.559	EPSD	GDSC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	Q9H211	CDT1	P24941	CDK2	S79	P83L	83	Missense	distal	4	no	12.445	12.556	EPSD	GDSC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	Q9H211	CDT1	P24941	CDK2	S81	T82P	82	Missense	proximal	1	no	3.045	13.002	EPSD	GDSC	8.148	Gain
CMGC_CDK_CDK2_CDK2_ST	Q9H211	CDT1	P24941	CDK2	T82	A85S	85	Missense	distal	3	no	13.985	14.531	EPSD	GDSC;CCLE	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	Q9H211	CDT1	P24941	CDK2	T82	T82P	82	Missense	central	0	yes	13.985	0.000	EPSD	GDSC	8.148	Loss
CMGC_CDK_CDK2_CDK2_ST	Q9H211	CDT1	P24941	CDK2	T82	P83L	83	Missense	proximal	1	no	13.985	4.165	EPSD	GDSC	8.148	Loss
CMGC_CDK_CDK2_CDK2_ST	Q9H211	CDT1	P24941	CDK2	S93	A90D	90	Missense	distal	-3	no	13.057	13.181	EPSD	GDSC;CCLE	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	Q9H211	CDT1	P24941	CDK2	T152	R158H	158	Missense	distal	6	no	11.611	11.622	EPSD	GDSC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	Q9H211	CDT1	P24941	CDK2	T213	T213K	213	Missense	central	0	yes	13.571	0.000	EPSD	GDSC;CCLE	8.148	Loss
CMGC_CDK_CDK2_CDK2_ST	Q9H211	CDT1	P24941	CDK2	S318	L314M	314	Missense	distal	-4	no	14.009	13.319	EPSD	GDSC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	Q9H211	CDT1	P24941	CDK2	S391	R396K	396	Missense	distal	5	no	13.572	13.412	EPSD	GDSC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	Q9H211	CDT1	P24941	CDK2	S391	A388T	388	Missense	distal	-3	no	13.572	13.591	EPSD	GDSC;CCLE	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	Q9H211	CDT1	P24941	CDK2	S394	R396K	396	Missense	proximal	2	no	15.927	15.627	EPSD	GDSC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	Q9H211	CDT1	P24941	CDK2	S394	A388T	388	Missense	distal	-6	no	15.927	15.928	EPSD	GDSC;CCLE	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	Q9H211	CDT1	P24941	CDK2	T402	R396K	396	Missense	distal	-6	no	14.160	14.158	EPSD	GDSC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	P25205	MCM3	P24941	CDK2	T464	D460N	460	Missense	distal	-4	no	15.123	14.735	EPSD	GDSC;CCLE	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	P25205	MCM3	P24941	CDK2	T464	P465T	465	Missense	proximal	1	no	15.123	5.166	EPSD	GDSC	8.148	Loss
CMGC_CDK_CDK2_CDK2_ST	P25205	MCM3	P24941	CDK2	S611	A615T	615	Missense	distal	4	no	13.274	13.517	EPSD	GDSC;CCLE	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	P25205	MCM3	P24941	CDK2	S611	S611Y	611	Missense	central	0	yes	13.274	0.000	EPSD	GDSC;CCLE	8.148	Loss
CMGC_CDK_CDK2_CDK2_ST	P25205	MCM3	P24941	CDK2	T722	T725M	725	Missense	distal	3	no	14.925	14.800	PhosphoSitePlus	GDSC;CCLE	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	P25205	MCM3	P24941	CDK2	T722	V720A	720	Missense	proximal	-2	no	14.925	15.591	PhosphoSitePlus	GDSC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	P25205	MCM3	P24941	CDK2	S728	T725M	725	Missense	distal	-3	no	8.690	9.098	EPSD	GDSC;CCLE	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	O75179	ANKRD17	P24941	CDK2	T913	P914H	914	Missense	proximal	1	no	12.811	6.053	EPSD	GDSC;CCLE	8.148	Loss
CMGC_CDK_CDK2_CDK2_ST	O75179	ANKRD17	P24941	CDK2	T913	H908N	908	Missense	distal	-5	no	12.811	12.783	EPSD	GDSC;CCLE	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	O75179	ANKRD17	P24941	CDK2	T1213	S1215N	1215	Missense	proximal	2	no	9.930	9.793	EPSD	GDSC;CCLE	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	O75179	ANKRD17	P24941	CDK2	S1220	S1215N	1215	Missense	distal	-5	no	13.395	13.458	EPSD	GDSC;CCLE	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	O75179	ANKRD17	P24941	CDK2	S1709	P1710S	1710	Missense	proximal	1	no	15.165	3.899	EPSD	GDSC;CCLE	8.148	Loss
CMGC_CDK_CDK2_CDK2_ST	O75179	ANKRD17	P24941	CDK2	S1940	P1941A	1941	Missense	proximal	1	no	11.413	-2.990	EPSD	GDSC;CCLE	8.148	Loss
CMGC_CDK_CDK2_CDK2_ST	O75179	ANKRD17	P24941	CDK2	T2279	S2278P	2278	Missense	proximal	-1	no	10.431	10.902	EPSD	GDSC;CCLE	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	O75179	ANKRD17	P24941	CDK2	S2318	M2325T	2325	Missense	distal	7	no	10.816	9.967	EPSD	GDSC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	O75179	ANKRD17	P24941	CDK2	S2318	N2324D	2324	Missense	distal	6	no	10.816	10.797	EPSD	GDSC;CCLE	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	O75179	ANKRD17	P24941	CDK2	T2509	R2502*	2502	Missense	distal	-7	no	14.493	14.624	EPSD	GDSC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	Q5JTZ9	AARS2	P24941	CDK2	T670	R663C	663	Missense	distal	-7	no	14.019	13.946	EPSD	GDSC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	Q5JTZ9	AARS2	P24941	CDK2	T673	A679V	679	Missense	distal	6	no	14.099	14.102	PhosphoSitePlus	GDSC;CCLE	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	Q14202	ZMYM3	P24941	CDK2	S51	P48S	48	Missense	distal	-3	no	15.483	15.578	EPSD	GDSC;CCLE	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	Q14202	ZMYM3	P24941	CDK2	S54	P48S	48	Missense	distal	-6	no	8.853	8.852	EPSD	GDSC;CCLE	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	Q14202	ZMYM3	P24941	CDK2	T62	T62A	62	Missense	central	0	yes	15.713	0.000	EPSD	GDSC;CCLE	8.148	Loss
CMGC_CDK_CDK2_CDK2_ST	Q14202	ZMYM3	P24941	CDK2	T62	E67K	67	Missense	distal	5	no	15.713	15.579	EPSD	GDSC;CCLE	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	Q14202	ZMYM3	P24941	CDK2	S91	V95G	95	Missense	distal	4	no	16.805	16.458	EPSD	GDSC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	Q14202	ZMYM3	P24941	CDK2	S91	A89T	89	Missense	proximal	-2	no	16.805	16.756	EPSD	GDSC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	Q14202	ZMYM3	P24941	CDK2	S148	P146S	146	Missense	proximal	-2	no	13.911	13.260	EPSD	GDSC;CCLE	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	Q14202	ZMYM3	P24941	CDK2	S582	Q579L	579	Missense	distal	-3	no	11.093	10.964	EPSD	GDSC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	Q14202	ZMYM3	P24941	CDK2	S582	R580C	580	Missense	proximal	-2	no	11.093	11.267	EPSD	GDSC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	Q14202	ZMYM3	P24941	CDK2	T1244	T1245P	1245	Missense	proximal	1	no	3.838	13.795	EPSD	GDSC	8.148	Gain
CMGC_CDK_CDK2_CDK2_ST	P15336	ATF2	P24941	CDK2	T69	V63A	63	Missense	distal	-6	no	14.316	14.313	EPSD	GDSC;CCLE	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	P15336	ATF2	P24941	CDK2	S136	Q134H	134	Missense	proximal	-2	no	12.538	12.095	EPSD	GDSC;CCLE	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	P15336	ATF2	P24941	CDK2	T325	H331L	331	Missense	distal	6	no	13.346	13.353	EPSD	GDSC;CCLE	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	P15336	ATF2	P24941	CDK2	S328	H331L	331	Missense	distal	3	no	12.868	11.463	EPSD	GDSC;CCLE	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	P15336	ATF2	P24941	CDK2	T333	H331L	331	Missense	proximal	-2	no	11.689	12.474	EPSD	GDSC;CCLE	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	Q9UKM9	RALY	P24941	CDK2	S110	D117E	117	Missense	distal	7	no	9.479	8.837	EPSD	GDSC;CCLE	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	Q9UKM9	RALY	P24941	CDK2	T286	G279S	279	Missense	distal	-7	no	9.134	8.630	EPSD	GDSC;CCLE	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	P78317	RNF4	P24941	CDK2	T26	A23G	23	Missense	distal	-3	no	13.011	13.173	PhosphoSitePlus;EPSD	GDSC;CCLE	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	P78317	RNF4	P24941	CDK2	S101	S94G	94	Missense	distal	-7	no	8.030	8.534	EPSD	GDSC;CCLE	8.148	Gain
CMGC_CDK_CDK2_CDK2_ST	Q13352	ITGB3BP	P24941	CDK2	T73	E77K	77	Missense	distal	4	no	7.905	8.290	EPSD	GDSC	8.148	Gain
CMGC_CDK_CDK2_CDK2_ST	P38936	CDKN1A	P24941	CDK2	T57	E56*	56	Missense	proximal	-1	no	15.802	15.919	EPSD	GDSC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	P38936	CDKN1A	P24941	CDK2	T80	P79H	79	Missense	proximal	-1	no	9.228	9.347	EPSD	GDSC;CCLE	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	P38936	CDKN1A	P24941	CDK2	T80	P79L	79	Missense	proximal	-1	no	9.228	9.048	EPSD	GDSC;CCLE	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	Q8WYH8	ING5	P24941	CDK2	S57	V62L	62	Missense	distal	5	no	12.411	12.484	EPSD	GDSC;CCLE	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	P50570	DNM2	P24941	CDK2	S762	P767L	767	Missense	distal	5	no	8.494	8.534	EPSD	GDSC;CCLE	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	P50570	DNM2	P24941	CDK2	S762	T766N	766	Missense	distal	4	no	8.494	8.191	EPSD	GDSC;CCLE	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	P50570	DNM2	P24941	CDK2	S764	R770*	770	Missense	distal	6	no	14.419	14.418	PhosphoSitePlus	GDSC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	P50570	DNM2	P24941	CDK2	S764	P767L	767	Missense	distal	3	no	14.419	14.036	PhosphoSitePlus	GDSC;CCLE	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	P50570	DNM2	P24941	CDK2	S764	T766N	766	Missense	proximal	2	no	14.419	14.526	PhosphoSitePlus	GDSC;CCLE	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	P50570	DNM2	P24941	CDK2	T766	R770*	770	Missense	distal	4	no	13.426	13.172	EPSD	GDSC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	P50570	DNM2	P24941	CDK2	T766	P767L	767	Missense	proximal	1	no	13.426	3.606	EPSD	GDSC;CCLE	8.148	Loss
CMGC_CDK_CDK2_CDK2_ST	P50570	DNM2	P24941	CDK2	T766	T766N	766	Missense	central	0	yes	13.426	0.000	EPSD	GDSC;CCLE	8.148	Loss
CMGC_CDK_CDK2_CDK2_ST	Q05209	PTPN12	P24941	CDK2	S19	N23T	23	Missense	distal	4	no	12.249	12.552	PhosphoSitePlus	GDSC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	Q05209	PTPN12	P24941	CDK2	T81	R74*	74	Missense	distal	-7	no	12.706	12.837	EPSD	GDSC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	Q05209	PTPN12	P24941	CDK2	T81	T78P	78	Missense	distal	-3	no	12.706	12.745	EPSD	GDSC;CCLE	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	Q05209	PTPN12	P24941	CDK2	S468	S466Y	466	Missense	proximal	-2	no	12.332	12.419	EPSD	GDSC;CCLE	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	Q05209	PTPN12	P24941	CDK2	T578	H584Y	584	Missense	distal	6	no	15.168	15.165	EPSD	GDSC;CCLE	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	Q05209	PTPN12	P24941	CDK2	S588	H584Y	584	Missense	distal	-4	no	13.554	14.623	EPSD	GDSC;CCLE	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	Q05209	PTPN12	P24941	CDK2	T693	E690K	690	Missense	distal	-3	no	14.328	14.113	EPSD	GDSC;CCLE	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	Q05209	PTPN12	P24941	CDK2	S704	Q703*	703	Missense	proximal	-1	no	8.016	9.226	EPSD	GDSC	8.148	Gain
CMGC_CDK_CDK2_CDK2_ST	Q05209	PTPN12	P24941	CDK2	S708	Q703*	703	Missense	distal	-5	no	10.006	10.096	EPSD	GDSC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	Q15788	NCOA1	P24941	CDK2	S16	S9F	9	Missense	distal	-7	no	8.173	8.724	EPSD	GDSC;CCLE	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	Q15788	NCOA1	P24941	CDK2	S22	T26P	26	Missense	distal	4	no	13.198	12.916	EPSD;PhosphoSitePlus	GDSC;CCLE	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	Q15788	NCOA1	P24941	CDK2	S192	S192G	192	Missense	central	0	yes	8.752	0.000	EPSD	GDSC;CCLE	8.148	Loss
CMGC_CDK_CDK2_CDK2_ST	Q15788	NCOA1	P24941	CDK2	S488	S482C	482	Missense	distal	-6	no	16.287	16.293	EPSD;PhosphoSitePlus	GDSC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	Q15788	NCOA1	P24941	CDK2	S488	I481T	481	Missense	distal	-7	no	16.287	16.090	EPSD;PhosphoSitePlus	GDSC;CCLE	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	Q15788	NCOA1	P24941	CDK2	T1179	P1180L	1180	Missense	proximal	1	no	13.578	3.757	EPSD;PhosphoSitePlus	GDSC;CCLE	8.148	Loss
CMGC_CDK_CDK2_CDK2_ST	Q15788	NCOA1	P24941	CDK2	S1185	P1180L	1180	Missense	distal	-5	no	14.076	14.088	EPSD;PhosphoSitePlus	GDSC;CCLE	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	Q15788	NCOA1	P24941	CDK2	T1426	G1423E	1423	Missense	distal	-3	no	12.764	12.835	EPSD;PhosphoSitePlus	GDSC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	Q15788	NCOA1	P24941	CDK2	T1426	S1422L	1422	Missense	distal	-4	no	12.764	12.351	EPSD;PhosphoSitePlus	GDSC;CCLE	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	P23771	GATA3	P24941	CDK2	T156	T152P	152	Missense	distal	-4	no	16.652	16.485	PhosphoSitePlus	GDSC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	P23771	GATA3	P24941	CDK2	S243	S238N	238	Missense	distal	-5	no	12.847	12.910	EPSD	GDSC;CCLE	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	Q15554	TERF2	P24941	CDK2	T169	E172Q	172	Missense	distal	3	no	12.341	11.694	EPSD	GDSC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	Q9UGP5	POLL	P24941	CDK2	T553	R549*	549	Missense	distal	-4	no	15.305	14.815	EPSD;PhosphoSitePlus	GDSC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	O94761	RECQL4	P24941	CDK2	S251	S256I	256	Missense	distal	5	no	14.684	14.878	PhosphoSitePlus;EPSD	GDSC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	P28324	ELK4	P24941	CDK2	S180	P181A	181	Missense	proximal	1	no	12.829	-1.575	EPSD	GDSC;CCLE	8.148	Loss
CMGC_CDK_CDK2_CDK2_ST	P28324	ELK4	P24941	CDK2	T185	P181A	181	Missense	distal	-4	no	12.322	12.264	EPSD	GDSC;CCLE	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	P28324	ELK4	P24941	CDK2	S215	I210V	210	Missense	distal	-5	no	12.434	12.426	EPSD	GDSC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	P03372	ESR1	P24941	CDK2	S294	K299N	299	Missense	distal	5	no	12.927	13.084	EPSD;PhosphoSitePlus	GDSC;CCLE	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	P03372	ESR1	P24941	CDK2	S294	I298V	298	Missense	distal	4	no	12.927	13.183	EPSD;PhosphoSitePlus	GDSC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	Q12778	FOXO1	P24941	CDK2	S218	L219P	219	Missense	proximal	1	no	2.419	12.240	EPSD	GDSC;CCLE	8.148	Gain
CMGC_CDK_CDK2_CDK2_ST	Q12778	FOXO1	P24941	CDK2	S329	T333A	333	Missense	distal	4	no	11.834	11.591	EPSD	GDSC;CCLE	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	Q12778	FOXO1	P24941	CDK2	S383	L381F	381	Missense	proximal	-2	no	15.642	14.753	EPSD	GDSC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	P12268	IMPDH2	P24941	CDK2	S122	S122N	122	Missense	central	0	yes	13.332	0.000	PhosphoSitePlus	GDSC	8.148	Loss
CMGC_CDK_CDK2_CDK2_ST	P12268	IMPDH2	P24941	CDK2	S122	P123R	123	Missense	proximal	1	no	13.332	3.534	PhosphoSitePlus	GDSC	8.148	Loss
CMGC_CDK_CDK2_CDK2_ST	O75533	SF3B1	P24941	CDK2	S129	E131*	131	Missense	proximal	2	no	18.222	18.298	EPSD	GDSC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	O75533	SF3B1	P24941	CDK2	T227	E234*	234	Missense	distal	7	no	13.378	13.763	EPSD	GDSC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	O75533	SF3B1	P24941	CDK2	T235	E234*	234	Missense	proximal	-1	no	15.794	15.912	EPSD	GDSC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	O75533	SF3B1	P24941	CDK2	T257	A263V	263	Missense	distal	6	no	15.238	15.240	EPSD	GDSC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	O75533	SF3B1	P24941	CDK2	S259	A263V	263	Missense	distal	4	no	8.642	8.829	EPSD	GDSC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	O75533	SF3B1	P24941	CDK2	T261	A263V	263	Missense	proximal	2	no	14.208	14.306	EPSD	GDSC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	O75533	SF3B1	P24941	CDK2	T267	T273A	273	Missense	distal	6	no	15.272	15.260	EPSD	GDSC;CCLE	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	O75533	SF3B1	P24941	CDK2	T267	A263V	263	Missense	distal	-4	no	15.272	15.283	EPSD	GDSC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	O75533	SF3B1	P24941	CDK2	T273	T273A	273	Missense	central	0	yes	16.321	0.000	EPSD	GDSC;CCLE	8.148	Loss
CMGC_CDK_CDK2_CDK2_ST	O75533	SF3B1	P24941	CDK2	T278	T273A	273	Missense	distal	-5	no	16.046	16.072	EPSD	GDSC;CCLE	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	Q99741	CDC6	P24941	CDK2	S45	R47H	47	Missense	proximal	2	no	15.739	15.658	EPSD	GDSC;CCLE	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	Q99741	CDC6	P24941	CDK2	S54	R47H	47	Missense	distal	-7	no	17.116	16.895	EPSD;PhosphoSitePlus	GDSC;CCLE	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	Q99741	CDC6	P24941	CDK2	T67	N66D	66	Missense	proximal	-1	no	11.591	12.420	EPSD	GDSC;CCLE	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	Q99741	CDC6	P24941	CDK2	T527	R528H	528	Missense	proximal	1	no	5.162	8.202	EPSD	GDSC;CCLE	8.148	Gain
CMGC_CDK_CDK2_CDK2_ST	P10644	PRKAR1A	P24941	CDK2	T209	L203H	203	Missense	distal	-6	no	13.976	13.980	EPSD	GDSC;CCLE	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	Q15003	NCAPH	P24941	CDK2	S28	V33L	33	Missense	distal	5	no	15.447	15.520	EPSD	GDSC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	Q15003	NCAPH	P24941	CDK2	S28	V33M	33	Missense	distal	5	no	15.447	15.788	EPSD	GDSC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	Q15003	NCAPH	P24941	CDK2	S81	D80V	80	Missense	proximal	-1	no	13.361	12.562	EPSD	GDSC;CCLE	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	Q15003	NCAPH	P24941	CDK2	S87	D80V	80	Missense	distal	-7	no	13.645	13.424	EPSD	GDSC;CCLE	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	Q15003	NCAPH	P24941	CDK2	S359	A354T	354	Missense	distal	-5	no	8.546	8.520	EPSD	GDSC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	Q15003	NCAPH	P24941	CDK2	S432	S437L	437	Missense	distal	5	no	14.715	14.855	EPSD	GDSC;CCLE	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	Q15003	NCAPH	P24941	CDK2	S589	C593*	593	Missense	distal	4	no	15.135	15.508	EPSD	GDSC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	Q15003	NCAPH	P24941	CDK2	S659	G660R	660	Missense	proximal	1	no	9.039	6.553	EPSD	GDSC	8.148	Loss
CMGC_CDK_CDK2_CDK2_ST	Q15003	NCAPH	P24941	CDK2	S659	A657V	657	Missense	proximal	-2	no	9.039	8.373	EPSD	GDSC;CCLE	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	Q15003	NCAPH	P24941	CDK2	S659	A665S	665	Missense	distal	6	no	9.039	9.044	EPSD	GDSC;CCLE	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	P30304	CDC25A	P24941	CDK2	S283	S287N	287	Missense	distal	4	no	15.804	15.770	PhosphoSitePlus	GDSC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	P30304	CDC25A	P24941	CDK2	S321	A319V	319	Missense	proximal	-2	no	13.607	12.941	EPSD	GDSC;CCLE	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	P30304	CDC25A	P24941	CDK2	S321	Q314*	314	Missense	distal	-7	no	13.607	14.125	EPSD	GDSC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	P33981	TTK	P24941	CDK2	S37	S37R	37	Missense	central	0	yes	8.595	0.000	EPSD	GDSC;CCLE	8.148	Loss
CMGC_CDK_CDK2_CDK2_ST	P33981	TTK	P24941	CDK2	S37	K40N	40	Missense	distal	3	no	8.595	5.325	EPSD	GDSC;CCLE	8.148	Loss
CMGC_CDK_CDK2_CDK2_ST	P33981	TTK	P24941	CDK2	S80	V77A	77	Missense	distal	-3	no	8.990	8.789	EPSD	GDSC;CCLE	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	P33981	TTK	P24941	CDK2	S281	P275T	275	Missense	distal	-6	no	8.574	8.573	EPSD	GDSC;CCLE	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	P33981	TTK	P24941	CDK2	S436	P438S	438	Missense	proximal	2	no	12.873	12.939	EPSD;PhosphoSitePlus	GDSC;CCLE	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	Q15813	TBCE	P24941	CDK2	T65	C61S	61	Missense	distal	-4	no	7.356	8.462	EPSD	GDSC;CCLE	8.148	Gain
CMGC_CDK_CDK2_CDK2_ST	Q15813	TBCE	P24941	CDK2	S495	K498E	498	Missense	distal	3	no	16.954	14.869	PhosphoSitePlus	GDSC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	Q53GL7	PARP10	P24941	CDK2	T101	Q103R	103	Missense	proximal	2	no	14.904	15.004	PhosphoSitePlus	GDSC;CCLE	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	Q53GL7	PARP10	P24941	CDK2	S128	R133W	133	Missense	distal	5	no	12.307	12.474	EPSD	GDSC;CCLE	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	Q53ET0	CRTC2	P24941	CDK2	S128	Y130C	130	Missense	proximal	2	no	15.585	15.672	EPSD	GDSC;CCLE	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	Q53ET0	CRTC2	P24941	CDK2	S131	Y130C	130	Missense	proximal	-1	no	13.335	12.768	EPSD	GDSC;CCLE	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	Q53ET0	CRTC2	P24941	CDK2	S136	Y130C	130	Missense	distal	-6	no	14.361	14.367	EPSD	GDSC;CCLE	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	Q53ET0	CRTC2	P24941	CDK2	T420	H426N	426	Missense	distal	6	no	13.202	13.211	EPSD	GDSC;CCLE	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	Q53ET0	CRTC2	P24941	CDK2	S424	H426N	426	Missense	proximal	2	no	14.789	14.641	EPSD	GDSC;CCLE	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	Q53ET0	CRTC2	P24941	CDK2	S433	H426N	426	Missense	distal	-7	no	13.266	13.061	PhosphoSitePlus	GDSC;CCLE	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	Q53ET0	CRTC2	P24941	CDK2	S456	Q449*	449	Missense	distal	-7	no	12.882	13.400	EPSD	GDSC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	Q53ET0	CRTC2	P24941	CDK2	S490	P485T	485	Missense	distal	-5	no	12.845	12.844	EPSD	GDSC;CCLE	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	Q53ET0	CRTC2	P24941	CDK2	T501	L505Q	505	Missense	distal	4	no	14.544	14.493	EPSD	GDSC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	O15350	TP73	P24941	CDK2	S145	K138N	138	Missense	distal	-7	no	14.672	14.637	EPSD	GDSC;CCLE	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	O15350	TP73	P24941	CDK2	S166	T167P	167	Missense	proximal	1	no	0.893	10.850	EPSD	GDSC	8.148	Gain
CMGC_CDK_CDK2_CDK2_ST	O15350	TP73	P24941	CDK2	T167	T167P	167	Missense	central	0	yes	13.388	0.000	EPSD	GDSC	8.148	Loss
CMGC_CDK_CDK2_CDK2_ST	P31943	HNRNPH1	P24941	CDK2	S272	G279C	279	Missense	distal	7	no	8.746	8.717	EPSD	GDSC;CCLE	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	Q99708	RBBP8	P24941	CDK2	S10	G9E	9	Missense	proximal	-1	no	13.152	12.889	EPSD	GDSC;CCLE	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	Q99708	RBBP8	P24941	CDK2	S347	G354R	354	Missense	distal	7	no	14.542	14.361	EPSD	GDSC;CCLE	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	Q99708	RBBP8	P24941	CDK2	S568	P569S	569	Missense	proximal	1	no	14.873	3.608	EPSD	GDSC;CCLE	8.148	Loss
CMGC_CDK_CDK2_CDK2_ST	Q99708	RBBP8	P24941	CDK2	T596	E597Q	597	Missense	proximal	1	no	7.232	8.486	EPSD	GDSC;CCLE	8.148	Gain
CMGC_CDK_CDK2_CDK2_ST	Q99708	RBBP8	P24941	CDK2	S679	K676N	676	Missense	distal	-3	no	10.646	10.708	EPSD	GDSC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	Q99708	RBBP8	P24941	CDK2	S679	S679G	679	Missense	central	0	yes	10.646	0.000	EPSD	GDSC;CCLE	8.148	Loss
CMGC_CDK_CDK2_CDK2_ST	Q99708	RBBP8	P24941	CDK2	S836	R837G	837	Missense	proximal	1	no	6.677	9.164	EPSD	GDSC;CCLE	8.148	Gain
CMGC_CDK_CDK2_CDK2_ST	Q9NYB0	TERF2IP	P24941	CDK2	S36	M29L	29	Missense	distal	-7	no	16.320	15.824	EPSD	GDSC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	Q9NYB0	TERF2IP	P24941	CDK2	S36	R40H	40	Missense	distal	4	no	16.320	16.202	EPSD	GDSC;CCLE	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	Q9NYB0	TERF2IP	P24941	CDK2	S269	D272G	272	Missense	distal	3	no	14.028	15.740	EPSD	GDSC;CCLE	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	A1KXE4	FAM168B	P24941	CDK2	T57	K60T	60	Missense	distal	3	no	17.826	15.004	PhosphoSitePlus	GDSC;CCLE	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	A1KXE4	FAM168B	P24941	CDK2	T57	G52D	52	Missense	distal	-5	no	17.826	17.804	PhosphoSitePlus	GDSC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	A1KXE4	FAM168B	P24941	CDK2	S64	K60T	60	Missense	distal	-4	no	14.588	14.835	EPSD	GDSC;CCLE	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	Q13330	MTA1	P24941	CDK2	S386	G379S	379	Missense	distal	-7	no	12.106	11.602	EPSD	GDSC;CCLE	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	Q13330	MTA1	P24941	CDK2	S386	A382V	382	Missense	distal	-4	no	12.106	12.117	EPSD	GDSC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	Q13330	MTA1	P24941	CDK2	T399	Y397H	397	Missense	proximal	-2	no	8.240	7.795	EPSD	GDSC;CCLE	8.148	Loss
CMGC_CDK_CDK2_CDK2_ST	Q13330	MTA1	P24941	CDK2	S449	S446N	446	Missense	distal	-3	no	13.678	13.604	EPSD	GDSC;CCLE	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	Q13330	MTA1	P24941	CDK2	S460	S457N	457	Missense	distal	-3	no	14.856	14.782	EPSD	GDSC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	Q96E09	FAM122A	P24941	CDK2	S19	P14L	14	Missense	distal	-5	no	12.120	12.131	EPSD	GDSC;CCLE	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	Q96E09	FAM122A	P24941	CDK2	S189	R195K	195	Missense	distal	6	no	13.770	13.795	EPSD	GDSC;CCLE	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	Q6P1N0	CC2D1A	P24941	CDK2	T120	E114K	114	Missense	distal	-6	no	15.093	15.091	EPSD	GDSC;CCLE	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	Q6P1N0	CC2D1A	P24941	CDK2	S208	T212P	212	Missense	distal	4	no	14.363	14.081	PhosphoSitePlus	GDSC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	Q6P1N0	CC2D1A	P24941	CDK2	S239	A233V	233	Missense	distal	-6	no	12.662	12.665	EPSD	GDSC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	Q6P1N0	CC2D1A	P24941	CDK2	S239	G241D	241	Missense	proximal	2	no	12.662	12.541	EPSD	GDSC;CCLE	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	Q6P1N0	CC2D1A	P24941	CDK2	S324	D321A	321	Missense	distal	-3	no	13.414	13.291	EPSD	GDSC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	Q6P1N0	CC2D1A	P24941	CDK2	T331	T338R	338	Missense	distal	7	no	13.394	14.188	EPSD	GDSC;CCLE	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	Q6P1N0	CC2D1A	P24941	CDK2	T669	P670L	670	Missense	proximal	1	no	13.449	3.628	EPSD	GDSC;CCLE	8.148	Loss
CMGC_CDK_CDK2_CDK2_ST	Q6P1N0	CC2D1A	P24941	CDK2	S674	P670L	670	Missense	distal	-4	no	9.643	9.585	EPSD	GDSC;CCLE	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	Q6P1N0	CC2D1A	P24941	CDK2	S674	D677N	677	Missense	distal	3	no	9.643	10.894	EPSD	GDSC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	Q6P1N0	CC2D1A	P24941	CDK2	S837	A834E	834	Missense	distal	-3	no	9.405	9.638	EPSD	GDSC;CCLE	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	Q53H80	AKIRIN2	P24941	CDK2	S125	P123R	123	Missense	proximal	-2	no	13.914	12.678	EPSD	GDSC;CCLE	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	P54198	HIRA	P24941	CDK2	T586	P587L	587	Missense	proximal	1	no	15.477	5.656	EPSD	GDSC	8.148	Loss
CMGC_CDK_CDK2_CDK2_ST	P54198	HIRA	P24941	CDK2	S769	I771V	771	Missense	proximal	2	no	11.894	12.039	EPSD	GDSC;CCLE	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	P54198	HIRA	P24941	CDK2	S775	I771V	771	Missense	distal	-4	no	14.723	14.825	EPSD	GDSC;CCLE	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	Q01167	FOXK2	P24941	CDK2	S170	K173N	173	Missense	distal	3	no	16.266	12.996	EPSD	GDSC;CCLE	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	Q01167	FOXK2	P24941	CDK2	S180	K173N	173	Missense	distal	-7	no	10.223	10.189	EPSD	GDSC;CCLE	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	Q01167	FOXK2	P24941	CDK2	S195	S199P	199	Missense	distal	4	no	14.585	14.572	EPSD	GDSC;CCLE	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	Q01167	FOXK2	P24941	CDK2	S199	S199P	199	Missense	central	0	yes	13.080	0.000	EPSD	GDSC;CCLE	8.148	Loss
CMGC_CDK_CDK2_CDK2_ST	Q01167	FOXK2	P24941	CDK2	S373	A372T	372	Missense	proximal	-1	no	14.662	14.669	PhosphoSitePlus;EPSD	GDSC;CCLE	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	Q01167	FOXK2	P24941	CDK2	T389	A387S	387	Missense	proximal	-2	no	12.721	12.054	EPSD	GDSC;CCLE	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	Q01167	FOXK2	P24941	CDK2	S428	Q433R	433	Missense	distal	5	no	14.799	14.945	EPSD;PhosphoSitePlus	GDSC;CCLE	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	P30307	CDC25C	P24941	CDK2	S472	M471T	471	Missense	proximal	-1	no	11.087	9.774	EPSD	GDSC;CCLE	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	Q9Y2K7	KDM2A	P24941	CDK2	T550	P551L	551	Missense	proximal	1	no	14.987	5.166	PhosphoSitePlus	GDSC;CCLE	8.148	Loss
CMGC_CDK_CDK2_CDK2_ST	Q9Y2K7	KDM2A	P24941	CDK2	S558	P551L	551	Missense	distal	-7	no	15.036	15.041	EPSD	GDSC;CCLE	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	Q9Y2K7	KDM2A	P24941	CDK2	S558	S558F	558	Missense	central	0	yes	15.036	0.000	EPSD	GDSC;CCLE	8.148	Loss
CMGC_CDK_CDK2_CDK2_ST	Q9Y2K7	KDM2A	P24941	CDK2	S558	P559S	559	Missense	proximal	1	no	15.036	3.770	EPSD	GDSC;CCLE	8.148	Loss
CMGC_CDK_CDK2_CDK2_ST	Q9Y2K7	KDM2A	P24941	CDK2	S562	S558F	558	Missense	distal	-4	no	8.245	7.283	EPSD	GDSC;CCLE	8.148	Loss
CMGC_CDK_CDK2_CDK2_ST	Q9Y2K7	KDM2A	P24941	CDK2	S562	R568Q	568	Missense	distal	6	no	8.245	8.267	EPSD	GDSC;CCLE	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	Q9Y2K7	KDM2A	P24941	CDK2	S562	P559S	559	Missense	distal	-3	no	8.245	8.340	EPSD	GDSC;CCLE	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	Q9Y2K7	KDM2A	P24941	CDK2	S731	H727P	727	Missense	distal	-4	no	12.131	12.735	EPSD	GDSC;CCLE	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	Q9Y2K7	KDM2A	P24941	CDK2	S781	P780S	780	Missense	proximal	-1	no	8.153	7.682	EPSD	GDSC;CCLE	8.148	Loss
CMGC_CDK_CDK2_CDK2_ST	Q9Y2K7	KDM2A	P24941	CDK2	S832	H831P	831	Missense	proximal	-1	no	14.498	14.379	EPSD	GDSC;CCLE	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	Q9Y2K7	KDM2A	P24941	CDK2	S832	V837M	837	Missense	distal	5	no	14.498	14.839	EPSD	GDSC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	Q9Y2K7	KDM2A	P24941	CDK2	T844	R847H	847	Missense	distal	3	no	14.667	13.971	EPSD	GDSC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	Q9Y2K7	KDM2A	P24941	CDK2	T844	T844N	844	Missense	central	0	yes	14.667	0.000	EPSD	GDSC;CCLE	8.148	Loss
CMGC_CDK_CDK2_CDK2_ST	Q9Y2K7	KDM2A	P24941	CDK2	T844	V837M	837	Missense	distal	-7	no	14.667	15.149	EPSD	GDSC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	Q9Y2K7	KDM2A	P24941	CDK2	T844	R847C	847	Missense	distal	3	no	14.667	8.303	EPSD	GDSC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	Q9Y2K7	KDM2A	P24941	CDK2	T844	R843L	843	Missense	proximal	-1	no	14.667	13.917	EPSD	GDSC;CCLE	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	Q14207	NPAT	P24941	CDK2	S102	S108R	108	Missense	distal	6	no	12.263	12.246	EPSD	GDSC;CCLE	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	Q14207	NPAT	P24941	CDK2	S102	S108C	108	Missense	distal	6	no	12.263	12.249	EPSD	GDSC;CCLE	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	Q14207	NPAT	P24941	CDK2	S207	A203T	203	Missense	distal	-4	no	16.393	16.618	EPSD	GDSC;CCLE	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	Q14207	NPAT	P24941	CDK2	T963	R966Q	966	Missense	distal	3	no	13.682	11.938	EPSD	GDSC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	Q14207	NPAT	P24941	CDK2	S1151	T1153A	1153	Missense	proximal	2	no	13.428	13.630	EPSD	GDSC;CCLE	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	P48200	IREB2	P24941	CDK2	T777	Y770H	770	Missense	distal	-7	no	14.247	14.244	EPSD	GDSC;CCLE	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	P48200	IREB2	P24941	CDK2	T777	F781L	781	Missense	distal	4	no	14.247	14.541	EPSD	GDSC;CCLE	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	P30050	RPL12	P24941	CDK2	S157	S157G	157	Missense	central	0	yes	9.198	0.000	EPSD	GDSC;CCLE	8.148	Loss
CMGC_CDK_CDK2_CDK2_ST	Q9NYF8	BCLAF1	P24941	CDK2	S104	R107*	107	Missense	distal	3	no	16.166	15.712	EPSD	GDSC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	Q9NYF8	BCLAF1	P24941	CDK2	S104	R107Q	107	Missense	distal	3	no	16.166	14.423	EPSD	GDSC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	Q9NYF8	BCLAF1	P24941	CDK2	S114	R107*	107	Missense	distal	-7	no	14.129	14.261	EPSD	GDSC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	Q9NYF8	BCLAF1	P24941	CDK2	S114	S112F	112	Missense	proximal	-2	no	14.129	13.667	EPSD	GDSC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	Q9NYF8	BCLAF1	P24941	CDK2	S114	S121P	121	Missense	distal	7	no	14.129	14.281	EPSD	GDSC;CCLE	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	Q9NYF8	BCLAF1	P24941	CDK2	S114	R107Q	107	Missense	distal	-7	no	14.129	13.743	EPSD	GDSC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	Q9NYF8	BCLAF1	P24941	CDK2	S114	R117S	117	Missense	distal	3	no	14.129	12.445	EPSD	GDSC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	Q9NYF8	BCLAF1	P24941	CDK2	S114	R117T	117	Missense	distal	3	no	14.129	12.296	EPSD	GDSC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	Q9NYF8	BCLAF1	P24941	CDK2	S114	R113S	113	Missense	proximal	-1	no	14.129	13.088	EPSD	GDSC;CCLE	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	Q9NYF8	BCLAF1	P24941	CDK2	S114	R113M	113	Missense	proximal	-1	no	14.129	14.608	EPSD	GDSC;CCLE	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	Q9NYF8	BCLAF1	P24941	CDK2	S138	S143Y	143	Missense	distal	5	no	16.318	16.493	EPSD	GDSC;CCLE	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	Q9NYF8	BCLAF1	P24941	CDK2	S148	P149T	149	Missense	proximal	1	no	14.186	4.229	EPSD	GDSC	8.148	Loss
CMGC_CDK_CDK2_CDK2_ST	Q9NYF8	BCLAF1	P24941	CDK2	S148	S143Y	143	Missense	distal	-5	no	14.186	14.255	EPSD	GDSC;CCLE	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	Q9NYF8	BCLAF1	P24941	CDK2	S153	P149T	149	Missense	distal	-4	no	12.146	12.312	EPSD	GDSC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	Q9NYF8	BCLAF1	P24941	CDK2	S177	E176*	176	Missense	proximal	-1	no	14.882	14.999	EPSD	GDSC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	Q9NYF8	BCLAF1	P24941	CDK2	S177	E175K	175	Missense	proximal	-2	no	14.882	15.483	EPSD	GDSC;CCLE	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	Q9NYF8	BCLAF1	P24941	CDK2	S205	S206P	206	Missense	proximal	1	no	2.311	13.577	EPSD	GDSC	8.148	Gain
CMGC_CDK_CDK2_CDK2_ST	Q9NYF8	BCLAF1	P24941	CDK2	S230	P236R	236	Missense	distal	6	no	11.833	11.817	EPSD	GDSC;CCLE	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	Q9NYF8	BCLAF1	P24941	CDK2	T234	P236R	236	Missense	proximal	2	no	13.445	13.603	EPSD	GDSC;CCLE	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	Q9NYF8	BCLAF1	P24941	CDK2	T257	V251A	251	Missense	distal	-6	no	11.189	11.186	EPSD	GDSC;CCLE	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	Q9NYF8	BCLAF1	P24941	CDK2	T257	A254S	254	Missense	distal	-3	no	11.189	11.342	EPSD	GDSC;CCLE	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	Q9NYF8	BCLAF1	P24941	CDK2	T257	T250R	250	Missense	distal	-7	no	11.189	11.535	EPSD	GDSC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	Q9NYF8	BCLAF1	P24941	CDK2	S268	G275D	275	Missense	distal	7	no	15.574	15.591	EPSD	GDSC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	Q9NYF8	BCLAF1	P24941	CDK2	S268	H267R	267	Missense	proximal	-1	no	15.574	16.026	EPSD	GDSC;CCLE	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	Q9NYF8	BCLAF1	P24941	CDK2	S285	N289S	289	Missense	distal	4	no	14.602	14.636	EPSD	GDSC;CCLE	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	Q9NYF8	BCLAF1	P24941	CDK2	S285	S281P	281	Missense	distal	-4	no	14.602	14.248	EPSD	GDSC;CCLE	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	Q9NYF8	BCLAF1	P24941	CDK2	S285	Q288H	288	Missense	distal	3	no	14.602	15.649	EPSD	GDSC;CCLE	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	Q9NYF8	BCLAF1	P24941	CDK2	S290	N289S	289	Missense	proximal	-1	no	13.271	12.874	EPSD	GDSC;CCLE	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	Q9NYF8	BCLAF1	P24941	CDK2	S290	Q288H	288	Missense	proximal	-2	no	13.271	12.828	EPSD	GDSC;CCLE	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	Q9NYF8	BCLAF1	P24941	CDK2	S300	A302E	302	Missense	proximal	2	no	17.632	17.704	EPSD	GDSC;CCLE	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	Q9NYF8	BCLAF1	P24941	CDK2	S300	R298*	298	Missense	proximal	-2	no	17.632	16.908	EPSD	GDSC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	Q9NYF8	BCLAF1	P24941	CDK2	S385	S385G	385	Missense	central	0	yes	8.344	0.000	EPSD	GDSC	8.148	Loss
CMGC_CDK_CDK2_CDK2_ST	Q9NYF8	BCLAF1	P24941	CDK2	S389	S385G	385	Missense	distal	-4	no	9.361	8.689	EPSD	GDSC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	Q9NYF8	BCLAF1	P24941	CDK2	T402	G399E	399	Missense	distal	-3	no	8.139	8.211	EPSD	GDSC	8.148	Gain
CMGC_CDK_CDK2_CDK2_ST	Q9NYF8	BCLAF1	P24941	CDK2	T494	Q499H	499	Missense	distal	5	no	8.177	8.295	EPSD	GDSC;CCLE	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	Q9NYF8	BCLAF1	P24941	CDK2	T494	T494I	494	Missense	central	0	yes	8.177	0.000	EPSD	GDSC;CCLE	8.148	Loss
CMGC_CDK_CDK2_CDK2_ST	Q9NYF8	BCLAF1	P24941	CDK2	S496	Q499H	499	Missense	distal	3	no	13.721	14.768	EPSD	GDSC;CCLE	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	Q9NYF8	BCLAF1	P24941	CDK2	S496	T494I	494	Missense	proximal	-2	no	13.721	13.600	EPSD	GDSC;CCLE	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	Q9NYF8	BCLAF1	P24941	CDK2	S512	L515I	515	Missense	distal	3	no	14.296	14.011	EPSD	GDSC;CCLE	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	Q9NYF8	BCLAF1	P24941	CDK2	S512	D507E	507	Missense	distal	-5	no	14.296	14.275	EPSD	GDSC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	Q9NYF8	BCLAF1	P24941	CDK2	S512	P514L	514	Missense	proximal	2	no	14.296	14.189	EPSD	GDSC;CCLE	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	Q9NYF8	BCLAF1	P24941	CDK2	S531	P532Q	532	Missense	proximal	1	no	13.753	5.841	EPSD	GDSC;CCLE	8.148	Loss
CMGC_CDK_CDK2_CDK2_ST	Q9NYF8	BCLAF1	P24941	CDK2	S542	E546D	546	Missense	distal	4	no	8.937	8.855	EPSD	GDSC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	Q9NYF8	BCLAF1	P24941	CDK2	S648	R654S	654	Missense	distal	6	no	14.636	14.654	EPSD	GDSC;CCLE	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	Q9NYF8	BCLAF1	P24941	CDK2	S648	I651M	651	Missense	distal	3	no	14.636	15.064	EPSD	GDSC;CCLE	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	Q9NYF8	BCLAF1	P24941	CDK2	S658	R654S	654	Missense	distal	-4	no	13.774	14.371	EPSD	GDSC;CCLE	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	Q9NYF8	BCLAF1	P24941	CDK2	S658	I651M	651	Missense	distal	-7	no	13.774	14.081	EPSD	GDSC;CCLE	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	Q9NYF8	BCLAF1	P24941	CDK2	S757	P758S	758	Missense	proximal	1	no	14.470	3.204	EPSD	GDSC	8.148	Loss
CMGC_CDK_CDK2_CDK2_ST	Q9NYF8	BCLAF1	P24941	CDK2	S760	P758S	758	Missense	proximal	-2	no	13.962	13.311	EPSD	GDSC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	Q9NYF8	BCLAF1	P24941	CDK2	S883	D890E	890	Missense	distal	7	no	9.117	8.474	EPSD	GDSC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	Q9NYF8	BCLAF1	P24941	CDK2	S884	D890E	890	Missense	distal	6	no	11.824	11.837	EPSD	GDSC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	Q9NYF8	BCLAF1	P24941	CDK2	T888	D890E	890	Missense	proximal	2	no	11.104	11.203	EPSD	GDSC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	Q9UM11	FZR1	P24941	CDK2	S36	S40L	40	Missense	distal	4	no	13.707	13.805	EPSD	GDSC;CCLE	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	Q9UM11	FZR1	P24941	CDK2	S40	S40L	40	Missense	central	0	yes	15.649	0.000	PhosphoSitePlus;EPSD	GDSC;CCLE	8.148	Loss
CMGC_CDK_CDK2_CDK2_ST	Q9Y2W1	THRAP3	P24941	CDK2	S119	R122*	122	Missense	distal	3	no	17.576	17.122	EPSD	GDSC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	Q9Y2W1	THRAP3	P24941	CDK2	S264	R263Q	263	Missense	proximal	-1	no	10.417	9.539	EPSD	GDSC;CCLE	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	Q9Y2W1	THRAP3	P24941	CDK2	S268	R263Q	263	Missense	distal	-5	no	12.706	12.659	EPSD	GDSC;CCLE	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	Q9Y2W1	THRAP3	P24941	CDK2	S310	K314N	314	Missense	distal	4	no	16.360	15.938	EPSD	GDSC;CCLE	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	Q9Y2W1	THRAP3	P24941	CDK2	S315	K314N	314	Missense	proximal	-1	no	11.071	11.097	EPSD	GDSC;CCLE	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	Q9Y2W1	THRAP3	P24941	CDK2	S682	K688R	688	Missense	distal	6	no	13.357	13.332	EPSD	GDSC;CCLE	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	Q9Y2W1	THRAP3	P24941	CDK2	T799	T796A	796	Missense	distal	-3	no	8.478	8.459	EPSD	GDSC;CCLE	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	Q9Y2W1	THRAP3	P24941	CDK2	T799	A792T	792	Missense	distal	-7	no	8.478	8.311	EPSD	GDSC;CCLE	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	Q9H425	C1orf198	P24941	CDK2	S17	D24G	24	Missense	distal	7	no	9.478	9.461	EPSD	GDSC;CCLE	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	P49736	MCM2	P24941	CDK2	S27	T25A	25	Missense	proximal	-2	no	15.798	15.848	EPSD;PhosphoSitePlus	GDSC;CCLE	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	P49736	MCM2	P24941	CDK2	S27	D22Y	22	Missense	distal	-5	no	15.798	15.765	EPSD;PhosphoSitePlus	GDSC;CCLE	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	P49736	MCM2	P24941	CDK2	S41	S40F	40	Missense	proximal	-1	no	15.832	17.089	PhosphoSitePlus;EPSD	GDSC;CCLE	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	P49736	MCM2	P24941	CDK2	S41	R44G	44	Missense	distal	3	no	15.832	14.013	PhosphoSitePlus;EPSD	GDSC;CCLE	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	P49736	MCM2	P24941	CDK2	S41	P42L	42	Missense	proximal	1	no	15.832	6.011	PhosphoSitePlus;EPSD	GDSC;CCLE	8.148	Loss
CMGC_CDK_CDK2_CDK2_ST	P49736	MCM2	P24941	CDK2	S53	E52Q	52	Missense	proximal	-1	no	8.480	7.387	EPSD;PhosphoSitePlus	GDSC;CCLE	8.148	Loss
CMGC_CDK_CDK2_CDK2_ST	P49736	MCM2	P24941	CDK2	S108	R115L	115	Missense	distal	7	no	9.985	9.526	EPSD;PhosphoSitePlus	GDSC;CCLE	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	P49736	MCM2	P24941	CDK2	T805	K807R	807	Missense	proximal	2	no	9.534	9.834	EPSD	GDSC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	P55273	CDKN2D	P24941	CDK2	T141	P142S	142	Missense	proximal	1	no	15.112	3.846	EPSD	GDSC	8.148	Loss
CMGC_CDK_CDK2_CDK2_ST	Q14191	WRN	P24941	CDK2	S426	D433G	433	Missense	distal	7	no	12.318	12.301	EPSD	GDSC;CCLE	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	Q14191	WRN	P24941	CDK2	T490	V487I	487	Missense	distal	-3	no	9.946	9.823	EPSD	GDSC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	Q14191	WRN	P24941	CDK2	T490	T490P	490	Missense	central	0	yes	9.946	0.000	EPSD	GDSC	8.148	Loss
CMGC_CDK_CDK2_CDK2_ST	Q14191	WRN	P24941	CDK2	T777	T781I	781	Missense	distal	4	no	9.156	8.844	EPSD	GDSC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	Q14191	WRN	P24941	CDK2	T777	T781A	781	Missense	distal	4	no	9.156	8.913	EPSD	GDSC;CCLE	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	Q14191	WRN	P24941	CDK2	S1292	G1298V	1298	Missense	distal	6	no	9.597	9.607	EPSD	GDSC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	Q7Z2Z1	TICRR	P24941	CDK2	S441	L448I	448	Missense	distal	7	no	13.855	13.882	EPSD	GDSC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	Q7Z2Z1	TICRR	P24941	CDK2	T486	P487L	487	Missense	proximal	1	no	12.195	2.374	EPSD	GDSC;CCLE	8.148	Loss
CMGC_CDK_CDK2_CDK2_ST	Q7Z2Z1	TICRR	P24941	CDK2	S489	P487L	487	Missense	proximal	-2	no	19.263	19.038	EPSD	GDSC;CCLE	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	Q7Z2Z1	TICRR	P24941	CDK2	S936	P934S	934	Missense	proximal	-2	no	10.012	9.361	EPSD	GDSC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	Q7Z2Z1	TICRR	P24941	CDK2	S1001	E1000D	1000	Missense	proximal	-1	no	16.333	16.304	PhosphoSitePlus;EPSD	GDSC;CCLE	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	Q7Z2Z1	TICRR	P24941	CDK2	S1001	I995T	995	Missense	distal	-6	no	16.333	16.331	PhosphoSitePlus;EPSD	GDSC;CCLE	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	Q7Z2Z1	TICRR	P24941	CDK2	S1057	P1058A	1058	Missense	proximal	1	no	11.084	-3.319	EPSD	GDSC;CCLE	8.148	Loss
CMGC_CDK_CDK2_CDK2_ST	Q7Z2Z1	TICRR	P24941	CDK2	S1064	G1071V	1071	Missense	distal	7	no	14.114	13.702	EPSD	GDSC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	Q7Z2Z1	TICRR	P24941	CDK2	S1064	P1058A	1058	Missense	distal	-6	no	14.114	14.112	EPSD	GDSC;CCLE	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	Q7Z2Z1	TICRR	P24941	CDK2	S1078	G1071V	1071	Missense	distal	-7	no	14.068	13.763	EPSD	GDSC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	Q7Z2Z1	TICRR	P24941	CDK2	S1078	S1074P	1074	Missense	distal	-4	no	14.068	13.713	EPSD	GDSC;CCLE	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	Q7Z2Z1	TICRR	P24941	CDK2	S1078	S1074F	1074	Missense	distal	-4	no	14.068	13.106	EPSD	GDSC;CCLE	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	Q7Z2Z1	TICRR	P24941	CDK2	T1134	K1140N	1140	Missense	distal	6	no	15.645	15.640	EPSD	GDSC;CCLE	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	Q7Z2Z1	TICRR	P24941	CDK2	S1141	P1142L	1142	Missense	proximal	1	no	12.640	2.819	EPSD	GDSC;CCLE	8.148	Loss
CMGC_CDK_CDK2_CDK2_ST	Q7Z2Z1	TICRR	P24941	CDK2	S1141	K1140N	1140	Missense	proximal	-1	no	12.640	12.667	EPSD	GDSC;CCLE	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	Q7Z2Z1	TICRR	P24941	CDK2	T1146	P1142L	1142	Missense	distal	-4	no	16.034	15.976	EPSD	GDSC;CCLE	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	Q7Z2Z1	TICRR	P24941	CDK2	T1146	K1140N	1140	Missense	distal	-6	no	16.034	16.033	EPSD	GDSC;CCLE	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	Q7Z2Z1	TICRR	P24941	CDK2	T1260	G1259A	1259	Missense	proximal	-1	no	12.789	11.470	EPSD	GDSC;CCLE	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	Q7Z2Z1	TICRR	P24941	CDK2	S1303	P1304S	1304	Missense	proximal	1	no	15.541	4.275	EPSD	GDSC;CCLE	8.148	Loss
CMGC_CDK_CDK2_CDK2_ST	Q7Z2Z1	TICRR	P24941	CDK2	T1307	P1304S	1304	Missense	distal	-3	no	13.313	13.408	EPSD	GDSC;CCLE	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	Q7Z2Z1	TICRR	P24941	CDK2	T1405	A1404T	1404	Missense	proximal	-1	no	13.966	13.973	EPSD	GDSC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	Q7Z2Z1	TICRR	P24941	CDK2	S1413	S1413N	1413	Missense	central	0	yes	13.924	0.000	EPSD	GDSC	8.148	Loss
CMGC_CDK_CDK2_CDK2_ST	Q7Z2Z1	TICRR	P24941	CDK2	S1413	P1414A	1414	Missense	proximal	1	no	13.924	-0.479	EPSD	GDSC;CCLE	8.148	Loss
CMGC_CDK_CDK2_CDK2_ST	Q7Z2Z1	TICRR	P24941	CDK2	S1517	P1521H	1521	Missense	distal	4	no	14.740	14.502	EPSD	GDSC;CCLE	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	Q7Z2Z1	TICRR	P24941	CDK2	S1555	A1554T	1554	Missense	proximal	-1	no	12.375	12.382	EPSD	GDSC;CCLE	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	Q7Z2Z1	TICRR	P24941	CDK2	S1623	K1616T	1616	Missense	distal	-7	no	8.531	8.576	EPSD	GDSC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	Q7Z2Z1	TICRR	P24941	CDK2	S1623	R1628C	1628	Missense	distal	5	no	8.531	8.659	EPSD	GDSC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	Q7Z2Z1	TICRR	P24941	CDK2	T1633	R1628C	1628	Missense	distal	-5	no	14.610	14.644	EPSD	GDSC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	Q7Z2Z1	TICRR	P24941	CDK2	S1670	T1677P	1677	Missense	distal	7	no	16.075	16.379	EPSD	GDSC;CCLE	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	Q7Z2Z1	TICRR	P24941	CDK2	T1678	T1677P	1677	Missense	proximal	-1	no	13.272	13.535	EPSD	GDSC;CCLE	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	Q7Z2Z1	TICRR	P24941	CDK2	T1732	L1735S	1735	Missense	distal	3	no	11.807	12.224	EPSD	GDSC;CCLE	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	Q7Z2Z1	TICRR	P24941	CDK2	T1828	V1835L	1835	Missense	distal	7	no	12.561	12.333	EPSD	GDSC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	Q7Z2Z1	TICRR	P24941	CDK2	S1881	S1884T	1884	Missense	distal	3	no	13.327	13.179	EPSD	GDSC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	Q7Z2Z1	TICRR	P24941	CDK2	S1881	S1884C	1884	Missense	distal	3	no	13.327	8.648	EPSD	GDSC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	Q7Z2Z1	TICRR	P24941	CDK2	T1898	T1896N	1896	Missense	proximal	-2	no	10.071	8.762	EPSD	GDSC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	Q7Z2Z1	TICRR	P24941	CDK2	T1898	K1901Q	1901	Missense	distal	3	no	10.071	7.339	EPSD	GDSC	8.148	Loss
CMGC_CDK_CDK2_CDK2_ST	P33991	MCM4	P24941	CDK2	T23	D28Y	28	Missense	distal	5	no	12.603	12.502	EPSD	GDSC;CCLE	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	P33991	MCM4	P24941	CDK2	S32	D28Y	28	Missense	distal	-4	no	13.864	13.803	EPSD;PhosphoSitePlus	GDSC;CCLE	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	P33991	MCM4	P24941	CDK2	S217	F218L	218	Missense	proximal	1	no	3.495	8.484	EPSD	GDSC;CCLE	8.148	Gain
CMGC_CDK_CDK2_CDK2_ST	P06401	PGR	P24941	CDK2	S130	A133S	133	Missense	distal	3	no	12.920	13.466	EPSD	GDSC;CCLE	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	P06401	PGR	P24941	CDK2	S130	C134*	134	Missense	distal	4	no	12.920	13.293	EPSD	GDSC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	P06401	PGR	P24941	CDK2	S162	R167Q	167	Missense	distal	5	no	13.200	13.054	EPSD;PhosphoSitePlus	GDSC;CCLE	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	P06401	PGR	P24941	CDK2	S345	A338P	338	Missense	distal	-7	no	13.491	13.327	EPSD	GDSC;CCLE	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	P06401	PGR	P24941	CDK2	S345	P342L	342	Missense	distal	-3	no	13.491	13.420	EPSD	GDSC;CCLE	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	P06401	PGR	P24941	CDK2	S400	E395G	395	Missense	distal	-5	no	15.850	15.892	EPSD;PhosphoSitePlus	GDSC;CCLE	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	P18858	LIG1	P24941	CDK2	S51	S51C	51	Missense	central	0	yes	16.386	0.000	EPSD;PhosphoSitePlus	GDSC;CCLE	8.148	Loss
CMGC_CDK_CDK2_CDK2_ST	P18858	LIG1	P24941	CDK2	S76	E71D	71	Missense	distal	-5	no	16.475	16.495	EPSD;PhosphoSitePlus	GDSC;CCLE	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	P18858	LIG1	P24941	CDK2	S419	I424T	424	Missense	distal	5	no	8.606	8.488	EPSD	GDSC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	P18858	LIG1	P24941	CDK2	S419	L414R	414	Missense	distal	-5	no	8.606	8.641	EPSD	GDSC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	P18858	LIG1	P24941	CDK2	S819	R825W	825	Missense	distal	6	no	13.515	13.507	EPSD	GDSC;CCLE	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	P18858	LIG1	P24941	CDK2	S901	Q906R	906	Missense	distal	5	no	9.483	9.629	EPSD	GDSC;CCLE	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	P18858	LIG1	P24941	CDK2	S913	Q906R	906	Missense	distal	-7	no	7.813	8.199	EPSD	GDSC;CCLE	8.148	Gain
CMGC_CDK_CDK2_CDK2_ST	Q96KS0	EGLN2	P24941	CDK2	S74	T72N	72	Missense	proximal	-2	no	17.052	15.743	EPSD	GDSC;CCLE	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	Q96KS0	EGLN2	P24941	CDK2	S130	E123K	123	Missense	distal	-7	no	15.587	15.450	PhosphoSitePlus	GDSC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	P15923	TCF3	P24941	CDK2	S102	A109S	109	Missense	distal	7	no	9.422	8.885	EPSD	GDSC;CCLE	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	P15923	TCF3	P24941	CDK2	S529	K522Q	522	Missense	distal	-7	no	13.756	13.761	EPSD	GDSC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	P15923	TCF3	P24941	CDK2	S529	P524L	524	Missense	distal	-5	no	13.756	13.768	EPSD	GDSC;CCLE	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	O60271	SPAG9	P24941	CDK2	S194	R195K	195	Missense	proximal	1	no	8.954	1.102	EPSD	GDSC	8.148	Loss
CMGC_CDK_CDK2_CDK2_ST	O60271	SPAG9	P24941	CDK2	T217	G224E	224	Missense	distal	7	no	14.361	13.735	EPSD	GDSC;CCLE	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	O60271	SPAG9	P24941	CDK2	T226	P227L	227	Missense	proximal	1	no	12.761	2.940	EPSD	GDSC;CCLE	8.148	Loss
CMGC_CDK_CDK2_CDK2_ST	O60271	SPAG9	P24941	CDK2	T226	G224E	224	Missense	proximal	-2	no	12.761	12.388	EPSD	GDSC;CCLE	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	O60271	SPAG9	P24941	CDK2	S242	K247Q	247	Missense	distal	5	no	10.039	10.053	EPSD	GDSC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	O60271	SPAG9	P24941	CDK2	S251	K247Q	247	Missense	distal	-4	no	15.066	14.929	EPSD	GDSC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	O60271	SPAG9	P24941	CDK2	T276	T275I	275	Missense	proximal	-1	no	13.104	13.350	EPSD	GDSC;CCLE	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	O60271	SPAG9	P24941	CDK2	T276	S283L	283	Missense	distal	7	no	13.104	13.287	EPSD	GDSC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	O60271	SPAG9	P24941	CDK2	T276	G271*	271	Missense	distal	-5	no	13.104	13.115	EPSD	GDSC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	O60271	SPAG9	P24941	CDK2	T348	S347F	347	Missense	proximal	-1	no	10.726	11.983	EPSD	GDSC;CCLE	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	O60271	SPAG9	P24941	CDK2	T586	P587S	587	Missense	proximal	1	no	15.392	4.126	PhosphoSitePlus	GDSC	8.148	Loss
CMGC_CDK_CDK2_CDK2_ST	P29374	ARID4A	P24941	CDK2	S455	E456G	456	Missense	proximal	1	no	7.455	9.308	EPSD	GDSC	8.148	Gain
CMGC_CDK_CDK2_CDK2_ST	P29374	ARID4A	P24941	CDK2	T498	D502N	502	Missense	distal	4	no	8.702	8.747	EPSD	GDSC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	P29374	ARID4A	P24941	CDK2	S698	D694G	694	Missense	distal	-4	no	8.165	7.320	EPSD	GDSC	8.148	Loss
CMGC_CDK_CDK2_CDK2_ST	P29374	ARID4A	P24941	CDK2	S698	S700G	700	Missense	proximal	2	no	8.165	8.216	EPSD	GDSC;CCLE	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	P29374	ARID4A	P24941	CDK2	S864	R870T	870	Missense	distal	6	no	20.135	20.159	PhosphoSitePlus;EPSD	GDSC;CCLE	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	P29374	ARID4A	P24941	CDK2	S882	Q883*	883	Missense	proximal	1	no	9.849	2.690	EPSD	GDSC	8.148	Loss
CMGC_CDK_CDK2_CDK2_ST	Q5TZA2	CROCC	P24941	CDK2	S488	L487R	487	Missense	proximal	-1	no	8.091	8.841	EPSD	GDSC;CCLE	8.148	Gain
CMGC_CDK_CDK2_CDK2_ST	Q5TZA2	CROCC	P24941	CDK2	T492	G489R	489	Missense	distal	-3	no	12.216	12.301	EPSD	GDSC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	Q5TZA2	CROCC	P24941	CDK2	T492	L487R	487	Missense	distal	-5	no	12.216	12.251	EPSD	GDSC;CCLE	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	Q5TZA2	CROCC	P24941	CDK2	S494	G489R	489	Missense	distal	-5	no	15.424	15.391	EPSD	GDSC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	Q5TZA2	CROCC	P24941	CDK2	S494	L487R	487	Missense	distal	-7	no	15.424	15.762	EPSD	GDSC;CCLE	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	Q5TZA2	CROCC	P24941	CDK2	S500	G502D	502	Missense	proximal	2	no	14.610	14.489	EPSD	GDSC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	Q5TZA2	CROCC	P24941	CDK2	S506	G502D	502	Missense	distal	-4	no	16.468	17.313	EPSD	GDSC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	Q5TZA2	CROCC	P24941	CDK2	S1490	T1495P	1495	Missense	distal	5	no	15.278	15.304	EPSD	GDSC;CCLE	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	Q5TZA2	CROCC	P24941	CDK2	S1496	T1495P	1495	Missense	proximal	-1	no	13.906	14.169	EPSD	GDSC;CCLE	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	Q5TZA2	CROCC	P24941	CDK2	S1499	T1495P	1495	Missense	distal	-4	no	15.359	15.193	EPSD	GDSC;CCLE	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	Q04637	EIF4G1	P24941	CDK2	T43	Q37*	37	Missense	distal	-6	no	9.718	9.724	EPSD	GDSC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	Q04637	EIF4G1	P24941	CDK2	S261	P264L	264	Missense	distal	3	no	15.733	15.349	EPSD	GDSC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	Q04637	EIF4G1	P24941	CDK2	S263	P264L	264	Missense	proximal	1	no	12.604	2.783	EPSD	GDSC	8.148	Loss
CMGC_CDK_CDK2_CDK2_ST	Q04637	EIF4G1	P24941	CDK2	T265	P264L	264	Missense	proximal	-1	no	12.353	12.174	EPSD	GDSC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	Q04637	EIF4G1	P24941	CDK2	S267	P264L	264	Missense	distal	-3	no	15.468	15.397	EPSD	GDSC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	Q04637	EIF4G1	P24941	CDK2	S269	S276C	276	Missense	distal	7	no	12.274	13.067	EPSD	GDSC;CCLE	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	Q04637	EIF4G1	P24941	CDK2	S269	P264L	264	Missense	distal	-5	no	12.274	12.285	EPSD	GDSC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	Q04637	EIF4G1	P24941	CDK2	S314	A321V	321	Missense	distal	7	no	13.252	13.125	EPSD	GDSC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	Q04637	EIF4G1	P24941	CDK2	S314	R312C	312	Missense	proximal	-2	no	13.252	13.426	EPSD	GDSC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	Q04637	EIF4G1	P24941	CDK2	T318	A321V	321	Missense	distal	3	no	12.217	13.337	EPSD	GDSC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	Q04637	EIF4G1	P24941	CDK2	T318	R312C	312	Missense	distal	-6	no	12.217	12.220	EPSD	GDSC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	Q04637	EIF4G1	P24941	CDK2	T489	P486S	486	Missense	distal	-3	no	11.968	12.064	EPSD	GDSC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	Q04637	EIF4G1	P24941	CDK2	T1179	D1175V	1175	Missense	distal	-4	no	15.298	14.723	EPSD	GDSC;CCLE	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	Q04637	EIF4G1	P24941	CDK2	S1271	L1275H	1275	Missense	distal	4	no	14.205	13.856	EPSD	GDSC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	Q04637	EIF4G1	P24941	CDK2	T1495	R1498Q	1498	Missense	distal	3	no	16.508	14.765	EPSD	GDSC;CCLE	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	Q9ULX3	NOB1	P24941	CDK2	T210	P211S	211	Missense	proximal	1	no	13.370	2.105	EPSD	GDSC;CCLE	8.148	Loss
CMGC_CDK_CDK2_CDK2_ST	Q9NRH3	TUBG2	P24941	CDK2	S32	E34K	34	Missense	proximal	2	no	11.518	11.281	EPSD	GDSC;CCLE	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	Q9NRH3	TUBG2	P24941	CDK2	S32	V37A	37	Missense	distal	5	no	11.518	11.561	EPSD	GDSC;CCLE	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	Q9NRH3	TUBG2	P24941	CDK2	T274	T274A	274	Missense	central	0	yes	11.231	0.000	EPSD	GDSC;CCLE	8.148	Loss
CMGC_CDK_CDK2_CDK2_ST	Q16204	CCDC6	P24941	CDK2	S395	H399Y	399	Missense	distal	4	no	13.293	13.730	EPSD	GDSC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	Q16204	CCDC6	P24941	CDK2	S413	P412A	412	Missense	proximal	-1	no	13.460	13.189	EPSD	GDSC;CCLE	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	Q16204	CCDC6	P24941	CDK2	S419	P412A	412	Missense	distal	-7	no	16.162	16.326	EPSD	GDSC;CCLE	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	Q16204	CCDC6	P24941	CDK2	T462	S459L	459	Missense	distal	-3	no	12.911	12.745	EPSD	GDSC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	Q12959	DLG1	P24941	CDK2	T209	V202D	202	Missense	distal	-7	no	16.030	16.251	EPSD	GDSC;CCLE	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	Q12959	DLG1	P24941	CDK2	T209	L207S	207	Missense	proximal	-2	no	16.030	15.603	EPSD	GDSC;CCLE	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	Q12959	DLG1	P24941	CDK2	S432	Q425L	425	Missense	distal	-7	no	11.350	11.398	EPSD	GDSC;CCLE	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	Q12959	DLG1	P24941	CDK2	S432	V427F	427	Missense	distal	-5	no	11.350	11.391	EPSD	GDSC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	Q86T82	USP37	P24941	CDK2	S2	P9L	9	Missense	distal	7	no	16.460	16.491	EPSD	GDSC;CCLE	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	Q86T82	USP37	P24941	CDK2	S735	T733A	733	Missense	proximal	-2	no	14.261	14.311	EPSD	GDSC;CCLE	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	Q86T82	USP37	P24941	CDK2	T738	T733A	733	Missense	distal	-5	no	10.268	10.294	EPSD	GDSC;CCLE	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	Q86T82	USP37	P24941	CDK2	T738	D744Y	744	Missense	distal	6	no	10.268	10.276	EPSD	GDSC;CCLE	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	Q86XL3	ANKLE2	P24941	CDK2	S259	S264A	264	Missense	distal	5	no	16.639	16.750	EPSD	GDSC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	Q86XL3	ANKLE2	P24941	CDK2	S268	S264A	264	Missense	distal	-4	no	15.872	15.459	EPSD	GDSC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	Q86XL3	ANKLE2	P24941	CDK2	T406	D401N	401	Missense	distal	-5	no	16.988	16.949	EPSD	GDSC;CCLE	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	Q86XL3	ANKLE2	P24941	CDK2	T751	S747G	747	Missense	distal	-4	no	13.354	12.681	EPSD	GDSC;CCLE	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	Q86XL3	ANKLE2	P24941	CDK2	S778	P779S	779	Missense	proximal	1	no	11.702	0.436	EPSD	GDSC;CCLE	8.148	Loss
CMGC_CDK_CDK2_CDK2_ST	Q86XL3	ANKLE2	P24941	CDK2	S778	A780V	780	Missense	proximal	2	no	11.702	11.800	EPSD	GDSC;CCLE	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	Q86XL3	ANKLE2	P24941	CDK2	S778	A780T	780	Missense	proximal	2	no	11.702	11.500	EPSD	GDSC;CCLE	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	Q9UKY1	ZHX1	P24941	CDK2	T36	P33S	33	Missense	distal	-3	no	15.400	15.495	EPSD	GDSC;CCLE	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	Q9UKY1	ZHX1	P24941	CDK2	S549	E548*	548	Missense	proximal	-1	no	12.037	12.154	EPSD	GDSC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	Q14676	MDC1	P24941	CDK2	T358	R359G	359	Missense	proximal	1	no	5.761	8.248	EPSD	GDSC;CCLE	8.148	Gain
CMGC_CDK_CDK2_CDK2_ST	Q14676	MDC1	P24941	CDK2	S505	D502N	502	Missense	distal	-3	no	12.135	12.090	EPSD	GDSC;CCLE	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	Q14676	MDC1	P24941	CDK2	S505	P506H	506	Missense	proximal	1	no	12.135	5.376	EPSD	GDSC;CCLE	8.148	Loss
CMGC_CDK_CDK2_CDK2_ST	Q14676	MDC1	P24941	CDK2	S505	R512K	512	Missense	distal	7	no	12.135	11.359	EPSD	GDSC;CCLE	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	Q14676	MDC1	P24941	CDK2	T725	L730I	730	Missense	distal	5	no	9.897	9.949	EPSD	GDSC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	Q14676	MDC1	P24941	CDK2	T725	G731D	731	Missense	distal	6	no	9.897	9.893	EPSD	GDSC;CCLE	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	Q14676	MDC1	P24941	CDK2	S882	E884K	884	Missense	proximal	2	no	14.584	14.346	EPSD	GDSC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	Q14676	MDC1	P24941	CDK2	S882	R885T	885	Missense	distal	3	no	14.584	12.751	EPSD	GDSC;CCLE	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	Q14676	MDC1	P24941	CDK2	S882	R887M	887	Missense	distal	5	no	14.584	14.786	EPSD	GDSC;CCLE	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	Q14676	MDC1	P24941	CDK2	T1116	T1109A	1109	Missense	distal	-7	no	13.217	13.384	EPSD	GDSC;CCLE	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	Q14676	MDC1	P24941	CDK2	T1116	P1117L	1117	Missense	proximal	1	no	13.217	3.396	EPSD	GDSC	8.148	Loss
CMGC_CDK_CDK2_CDK2_ST	Q14676	MDC1	P24941	CDK2	S1130	T1131P	1131	Missense	proximal	1	no	3.819	13.776	EPSD	GDSC	8.148	Gain
CMGC_CDK_CDK2_CDK2_ST	Q14676	MDC1	P24941	CDK2	T1131	S1132P	1132	Missense	proximal	1	no	0.162	11.428	EPSD	GDSC	8.148	Gain
CMGC_CDK_CDK2_CDK2_ST	Q14676	MDC1	P24941	CDK2	T1138	T1131P	1131	Missense	distal	-7	no	13.128	13.131	EPSD	GDSC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	Q14676	MDC1	P24941	CDK2	T1138	A1134V	1134	Missense	distal	-4	no	13.128	13.139	EPSD	GDSC;CCLE	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	Q14676	MDC1	P24941	CDK2	T1138	S1132P	1132	Missense	distal	-6	no	13.128	13.129	EPSD	GDSC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	Q14676	MDC1	P24941	CDK2	T1198	T1205A	1205	Missense	distal	7	no	12.162	12.850	EPSD	GDSC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	Q14676	MDC1	P24941	CDK2	T1239	N1233S	1233	Missense	distal	-6	no	12.488	12.487	EPSD	GDSC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	Q14676	MDC1	P24941	CDK2	T1280	V1278G	1278	Missense	proximal	-2	no	12.563	12.470	EPSD	GDSC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	Q14676	MDC1	P24941	CDK2	T1302	V1301L	1301	Missense	proximal	-1	no	12.215	12.078	EPSD	GDSC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	Q14676	MDC1	P24941	CDK2	T1526	V1524L	1524	Missense	proximal	-2	no	12.329	12.755	EPSD	GDSC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	Q14676	MDC1	P24941	CDK2	T1526	P1527H	1527	Missense	proximal	1	no	12.329	5.571	EPSD	GDSC	8.148	Loss
CMGC_CDK_CDK2_CDK2_ST	Q14676	MDC1	P24941	CDK2	T1589	S1583C	1583	Missense	distal	-6	no	12.947	12.953	EPSD	GDSC;CCLE	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	Q14676	MDC1	P24941	CDK2	T1622	T1623P	1623	Missense	proximal	1	no	2.033	11.990	EPSD	GDSC	8.148	Gain
CMGC_CDK_CDK2_CDK2_ST	Q14676	MDC1	P24941	CDK2	T1630	P1628L	1628	Missense	proximal	-2	no	12.643	12.418	PhosphoSitePlus;EPSD	GDSC;CCLE	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	Q14676	MDC1	P24941	CDK2	T1630	T1623P	1623	Missense	distal	-7	no	12.643	12.645	PhosphoSitePlus;EPSD	GDSC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	Q14676	MDC1	P24941	CDK2	T1697	E1699K	1699	Missense	proximal	2	no	14.653	14.415	EPSD	GDSC;CCLE	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	Q14676	MDC1	P24941	CDK2	S1702	E1699K	1699	Missense	distal	-3	no	11.919	11.703	EPSD	GDSC;CCLE	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	Q14676	MDC1	P24941	CDK2	T1800	P1801T	1801	Missense	proximal	1	no	11.916	1.959	EPSD	GDSC;CCLE	8.148	Loss
CMGC_CDK_CDK2_CDK2_ST	Q8WXE1	ATRIP	P24941	CDK2	T26	H28Q	28	Missense	proximal	2	no	10.946	10.927	EPSD	GDSC;CCLE	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	Q8WXE1	ATRIP	P24941	CDK2	S239	P235L	235	Missense	distal	-4	no	12.341	12.283	EPSD	GDSC;CCLE	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	Q8WXE1	ATRIP	P24941	CDK2	S239	G243E	243	Missense	distal	4	no	12.341	12.478	EPSD	GDSC;CCLE	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	P06748	NPM1	P24941	CDK2	T219	P220L	220	Missense	proximal	1	no	13.177	3.356	EPSD	GDSC;CCLE	8.148	Loss
CMGC_CDK_CDK2_CDK2_ST	P06748	NPM1	P24941	CDK2	T234	P235S	235	Missense	proximal	1	no	11.174	-0.092	EPSD;PhosphoSitePlus	GDSC;CCLE	8.148	Loss
CMGC_CDK_CDK2_CDK2_ST	P06748	NPM1	P24941	CDK2	T237	P235S	235	Missense	proximal	-2	no	11.064	10.413	EPSD	GDSC;CCLE	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	Q9BZL4	PPP1R12C	P24941	CDK2	S325	S327N	327	Missense	proximal	2	no	8.432	8.295	EPSD	GDSC;CCLE	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	Q9BZL4	PPP1R12C	P24941	CDK2	S399	G396D	396	Missense	distal	-3	no	15.462	15.424	EPSD	GDSC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	Q9BZL4	PPP1R12C	P24941	CDK2	S404	P408S	408	Missense	distal	4	no	11.770	11.784	EPSD	GDSC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	Q9BZL4	PPP1R12C	P24941	CDK2	S407	P408S	408	Missense	proximal	1	no	15.378	4.112	EPSD	GDSC	8.148	Loss
CMGC_CDK_CDK2_CDK2_ST	Q9BZL4	PPP1R12C	P24941	CDK2	S544	K547N	547	Missense	distal	3	no	9.059	5.789	EPSD	GDSC;CCLE	8.148	Loss
CMGC_CDK_CDK2_CDK2_ST	Q13416	ORC2	P24941	CDK2	T226	R230T	230	Missense	distal	4	no	14.715	15.118	EPSD;PhosphoSitePlus	GDSC;CCLE	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	Q13416	ORC2	P24941	CDK2	S280	V279F	279	Missense	proximal	-1	no	14.755	15.584	EPSD	GDSC;CCLE	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	Q13416	ORC2	P24941	CDK2	S280	R273C	273	Missense	distal	-7	no	14.755	14.682	EPSD	GDSC;CCLE	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	Q96II8	LRCH3	P24941	CDK2	S255	I260M	260	Missense	distal	5	no	12.407	12.622	EPSD	GDSC;CCLE	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	Q96II8	LRCH3	P24941	CDK2	S318	S318N	318	Missense	central	0	yes	10.169	0.000	EPSD	GDSC;CCLE	8.148	Loss
CMGC_CDK_CDK2_CDK2_ST	Q96II8	LRCH3	P24941	CDK2	S419	V421L	421	Missense	proximal	2	no	18.277	18.048	PhosphoSitePlus	GDSC;CCLE	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	Q96II8	LRCH3	P24941	CDK2	S516	P517S	517	Missense	proximal	1	no	18.026	6.760	EPSD	GDSC;CCLE	8.148	Loss
CMGC_CDK_CDK2_CDK2_ST	Q96II8	LRCH3	P24941	CDK2	S583	P584H	584	Missense	proximal	1	no	13.961	7.203	EPSD	GDSC;CCLE	8.148	Loss
CMGC_CDK_CDK2_CDK2_ST	Q12800	TFCP2	P24941	CDK2	S309	N311S	311	Missense	proximal	2	no	18.016	18.153	EPSD;PhosphoSitePlus	GDSC;CCLE	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	Q02535	ID3	P24941	CDK2	S5	C10F	10	Missense	distal	5	no	12.741	12.725	PhosphoSitePlus	GDSC;CCLE	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	Q02535	ID3	P24941	CDK2	S5	E12Q	12	Missense	distal	7	no	12.741	12.542	PhosphoSitePlus	GDSC;CCLE	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	P06400	RB1	P24941	CDK2	S567	W563*	563	Missense	distal	-4	no	12.510	12.777	EPSD;PhosphoSitePlus	GDSC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	P06400	RB1	P24941	CDK2	S567	S567*	567	Missense	central	0	yes	12.510	0.000	EPSD;PhosphoSitePlus	GDSC	8.148	Loss
CMGC_CDK_CDK2_CDK2_ST	P06400	RB1	P24941	CDK2	S608	T601S	601	Missense	distal	-7	no	15.720	15.542	EPSD;PhosphoSitePlus	GDSC;CCLE	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	P06400	RB1	P24941	CDK2	S780	R787*	787	Missense	distal	7	no	13.523	13.463	EPSD	GDSC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	P06400	RB1	P24941	CDK2	S788	R787*	787	Missense	proximal	-1	no	15.922	16.253	EPSD	GDSC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	P06400	RB1	P24941	CDK2	S795	G801*	801	Missense	distal	6	no	14.101	14.095	EPSD	GDSC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	P06400	RB1	P24941	CDK2	S807	G801*	801	Missense	distal	-6	no	16.149	16.155	EPSD;PhosphoSitePlus	GDSC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	P06400	RB1	P24941	CDK2	T821	L819V	819	Missense	proximal	-2	no	14.278	13.853	EPSD;PhosphoSitePlus	GDSC;CCLE	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	P06400	RB1	P24941	CDK2	T826	L819V	819	Missense	distal	-7	no	15.388	15.402	EPSD;PhosphoSitePlus	GDSC;CCLE	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	O00267	SUPT5H	P24941	CDK2	S120	R124L	124	Missense	distal	4	no	9.341	9.574	EPSD	GDSC;CCLE	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	O00267	SUPT5H	P24941	CDK2	S686	G682D	682	Missense	distal	-4	no	14.410	15.254	EPSD	GDSC;CCLE	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	O00267	SUPT5H	P24941	CDK2	T806	G811D	811	Missense	distal	5	no	17.093	17.140	EPSD	GDSC;CCLE	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	O00267	SUPT5H	P24941	CDK2	T806	D810G	810	Missense	distal	4	no	17.093	17.038	EPSD	GDSC;CCLE	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	O00267	SUPT5H	P24941	CDK2	T814	G811D	811	Missense	distal	-3	no	13.463	13.424	EPSD	GDSC;CCLE	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	O00267	SUPT5H	P24941	CDK2	T814	D810G	810	Missense	distal	-4	no	13.463	12.618	EPSD	GDSC;CCLE	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	O00267	SUPT5H	P24941	CDK2	T828	T828M	828	Missense	central	0	yes	15.154	0.000	EPSD	GDSC;CCLE	8.148	Loss
CMGC_CDK_CDK2_CDK2_ST	O00267	SUPT5H	P24941	CDK2	S867	Q869L	869	Missense	proximal	2	no	15.527	15.361	EPSD	GDSC;CCLE	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	Q9UQR0	SCML2	P24941	CDK2	T20	Q17K	17	Missense	distal	-3	no	13.411	13.312	EPSD	GDSC;CCLE	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	Q9UQR0	SCML2	P24941	CDK2	S267	S264*	264	Missense	distal	-3	no	13.843	14.066	EPSD	GDSC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	Q9UQR0	SCML2	P24941	CDK2	S267	I274T	274	Missense	distal	7	no	13.843	13.482	EPSD	GDSC;CCLE	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	P10275	AR	P24941	CDK2	S516	E523D	523	Missense	distal	7	no	9.037	9.680	EPSD	GDSC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	O43395	PRPF3	P24941	CDK2	S133	E132K	132	Missense	proximal	-1	no	14.346	13.461	EPSD	GDSC;CCLE	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	O43395	PRPF3	P24941	CDK2	S164	P170T	170	Missense	distal	6	no	13.379	13.386	EPSD	GDSC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	O43395	PRPF3	P24941	CDK2	T167	P170T	170	Missense	distal	3	no	14.827	14.713	PhosphoSitePlus	GDSC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	O43395	PRPF3	P24941	CDK2	T172	P170T	170	Missense	proximal	-2	no	13.442	13.408	EPSD	GDSC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	O43395	PRPF3	P24941	CDK2	T254	P255T	255	Missense	proximal	1	no	11.765	1.808	EPSD	GDSC;CCLE	8.148	Loss
CMGC_CDK_CDK2_CDK2_ST	O43395	PRPF3	P24941	CDK2	S619	K625N	625	Missense	distal	6	no	9.117	9.112	EPSD	GDSC;CCLE	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	O43395	PRPF3	P24941	CDK2	S619	D620N	620	Missense	proximal	1	no	9.117	-23.251	EPSD	GDSC;CCLE	8.148	Loss
CMGC_CDK_CDK2_CDK2_ST	Q9Y676	MRPS18B	P24941	CDK2	T242	A244V	244	Missense	proximal	2	no	14.647	14.745	EPSD	GDSC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	Q9Y676	MRPS18B	P24941	CDK2	T242	T242I	242	Missense	central	0	yes	14.647	0.000	EPSD	GDSC	8.148	Loss
CMGC_CDK_CDK2_CDK2_ST	P46527	CDKN1B	P24941	CDK2	S178	G177S	177	Missense	proximal	-1	no	15.197	13.677	EPSD	GDSC;CCLE	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	Q13415	ORC1	P24941	CDK2	S199	K193M	193	Missense	distal	-6	no	13.086	13.093	EPSD	GDSC;CCLE	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	Q13415	ORC1	P24941	CDK2	S273	T272I	272	Missense	proximal	-1	no	16.209	16.455	PhosphoSitePlus;EPSD	GDSC;CCLE	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	Q13415	ORC1	P24941	CDK2	T428	R433G	433	Missense	distal	5	no	14.917	14.937	EPSD	GDSC;CCLE	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	Q13415	ORC1	P24941	CDK2	S610	S610L	610	Missense	central	0	yes	16.736	0.000	EPSD	GDSC;CCLE	8.148	Loss
CMGC_CDK_CDK2_CDK2_ST	Q13415	ORC1	P24941	CDK2	S610	T607A	607	Missense	distal	-3	no	16.736	16.717	EPSD	GDSC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	P54132	BLM	P24941	CDK2	T57	L60I	60	Missense	distal	3	no	14.943	14.658	EPSD	GDSC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	P54132	BLM	P24941	CDK2	S144	T150A	150	Missense	distal	6	no	15.323	15.311	EPSD	GDSC;CCLE	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	P54132	BLM	P24941	CDK2	S304	E307G	307	Missense	distal	3	no	12.972	12.249	EPSD	GDSC;CCLE	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	P54132	BLM	P24941	CDK2	S328	K323R	323	Missense	distal	-5	no	9.400	9.444	EPSD	GDSC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	P54132	BLM	P24941	CDK2	S426	D420H	420	Missense	distal	-6	no	9.048	9.054	EPSD	GDSC;CCLE	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	P54132	BLM	P24941	CDK2	S464	H457R	457	Missense	distal	-7	no	10.585	10.805	EPSD	GDSC;CCLE	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	P54132	BLM	P24941	CDK2	S714	V721A	721	Missense	distal	7	no	14.707	14.833	EPSD	GDSC;CCLE	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	P54132	BLM	P24941	CDK2	T766	V765I	765	Missense	proximal	-1	no	16.368	16.394	EPSD	GDSC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	P54132	BLM	P24941	CDK2	T907	D906N	906	Missense	proximal	-1	no	9.347	8.517	EPSD	GDSC;CCLE	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	O00429	DNM1L	P24941	CDK2	S136	P137T	137	Missense	proximal	1	no	16.362	6.405	EPSD	GDSC	8.148	Loss
CMGC_CDK_CDK2_CDK2_ST	O00429	DNM1L	P24941	CDK2	S136	V139I	139	Missense	distal	3	no	16.362	15.086	EPSD	GDSC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	O00429	DNM1L	P24941	CDK2	S548	A551T	551	Missense	distal	3	no	14.167	14.565	EPSD	GDSC;CCLE	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	O00429	DNM1L	P24941	CDK2	S548	P547L	547	Missense	proximal	-1	no	14.167	13.988	EPSD	GDSC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	O00429	DNM1L	P24941	CDK2	S548	A550D	550	Missense	proximal	2	no	14.167	14.140	EPSD	GDSC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	P28749	RBL1	P24941	CDK2	S762	T769I	769	Missense	distal	7	no	13.711	14.071	EPSD	GDSC;CCLE	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	P28749	RBL1	P24941	CDK2	S762	S757*	757	Missense	distal	-5	no	13.711	13.845	EPSD	GDSC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	P28749	RBL1	P24941	CDK2	S920	S919F	919	Missense	proximal	-1	no	7.694	8.951	EPSD	GDSC;CCLE	8.148	Gain
CMGC_CDK_CDK2_CDK2_ST	P28749	RBL1	P24941	CDK2	S975	P973T	973	Missense	proximal	-2	no	15.212	15.179	EPSD	GDSC;CCLE	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	P28749	RBL1	P24941	CDK2	T997	L1003P	1003	Missense	distal	6	no	15.469	15.468	EPSD	GDSC;CCLE	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	Q92547	TOPBP1	P24941	CDK2	T298	N295S	295	Missense	distal	-3	no	13.774	13.849	EPSD	GDSC;CCLE	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	Q92547	TOPBP1	P24941	CDK2	T298	P299R	299	Missense	proximal	1	no	13.774	3.976	EPSD	GDSC;CCLE	8.148	Loss
CMGC_CDK_CDK2_CDK2_ST	Q92547	TOPBP1	P24941	CDK2	S370	C367W	367	Missense	distal	-3	no	10.388	10.555	EPSD	GDSC;CCLE	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	Q92547	TOPBP1	P24941	CDK2	T779	P780S	780	Missense	proximal	1	no	11.270	0.004	EPSD	GDSC;CCLE	8.148	Loss
CMGC_CDK_CDK2_CDK2_ST	Q92547	TOPBP1	P24941	CDK2	T1501	T1501N	1501	Missense	central	0	yes	8.246	0.000	EPSD	GDSC;CCLE	8.148	Loss
CMGC_CDK_CDK2_CDK2_ST	Q9UEY8	ADD3	P24941	CDK2	S42	R46*	46	Missense	distal	4	no	14.917	14.662	EPSD	GDSC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	Q9UEY8	ADD3	P24941	CDK2	S108	G105S	105	Missense	distal	-3	no	11.625	11.616	EPSD	GDSC;CCLE	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	Q9UEY8	ADD3	P24941	CDK2	S360	Q362E	362	Missense	proximal	2	no	11.189	11.227	EPSD	GDSC;CCLE	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	Q9UEY8	ADD3	P24941	CDK2	S423	P424L	424	Missense	proximal	1	no	17.772	7.951	PhosphoSitePlus	GDSC	8.148	Loss
CMGC_CDK_CDK2_CDK2_ST	Q9UEY8	ADD3	P24941	CDK2	S423	V420A	420	Missense	distal	-3	no	17.772	17.570	PhosphoSitePlus	GDSC;CCLE	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	Q9UEY8	ADD3	P24941	CDK2	S423	T419A	419	Missense	distal	-4	no	17.772	17.546	PhosphoSitePlus	GDSC;CCLE	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	Q9UEY8	ADD3	P24941	CDK2	T481	S474L	474	Missense	distal	-7	no	15.493	15.679	EPSD	GDSC;CCLE	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	Q9UEY8	ADD3	P24941	CDK2	S681	K688E	688	Missense	distal	7	no	16.946	17.276	EPSD	GDSC;CCLE	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	Q9UEY8	ADD3	P24941	CDK2	T691	K688E	688	Missense	distal	-3	no	14.131	14.346	EPSD	GDSC;CCLE	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	Q0VD86	INCA1	P24941	CDK2	S23	R27M	27	Missense	distal	4	no	14.291	13.990	EPSD;PhosphoSitePlus	GDSC;CCLE	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	Q0VD86	INCA1	P24941	CDK2	S23	R22*	22	Missense	proximal	-1	no	14.291	14.622	EPSD;PhosphoSitePlus	GDSC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	P25098	GRK2	P24941	CDK2	S389	K383E	383	Missense	distal	-6	no	17.367	17.369	EPSD	GDSC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	P25098	GRK2	P24941	CDK2	S389	P390L	390	Missense	proximal	1	no	17.367	7.546	EPSD	GDSC	8.148	Loss
CMGC_CDK_CDK2_CDK2_ST	P42677	RPS27	P24941	CDK2	S11	L7H	7	Missense	distal	-4	no	11.693	11.148	EPSD	GDSC;CCLE	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	P42677	RPS27	P24941	CDK2	S11	E13D	13	Missense	proximal	2	no	11.693	11.593	EPSD	GDSC;CCLE	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	P42677	RPS27	P24941	CDK2	S11	P10L	10	Missense	proximal	-1	no	11.693	11.514	EPSD	GDSC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	P42677	RPS27	P24941	CDK2	S27	S27I	27	Missense	central	0	yes	15.410	0.000	PhosphoSitePlus	GDSC;CCLE	8.148	Loss
CMGC_CDK_CDK2_CDK2_ST	O00311	CDC7	P24941	CDK2	S16	R21Q	21	Missense	distal	5	no	15.438	15.291	EPSD	GDSC;CCLE	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	O00311	CDC7	P24941	CDK2	S302	S299L	299	Missense	distal	-3	no	13.608	13.441	EPSD	GDSC;CCLE	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	O00311	CDC7	P24941	CDK2	T376	E383*	383	Missense	distal	7	no	12.843	13.228	PhosphoSitePlus	GDSC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	O00311	CDC7	P24941	CDK2	T376	Q369L	369	Missense	distal	-7	no	12.843	12.892	PhosphoSitePlus	GDSC;CCLE	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	O00311	CDC7	P24941	CDK2	T503	Q507L	507	Missense	distal	4	no	13.262	13.313	EPSD	GDSC;CCLE	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	O00311	CDC7	P24941	CDK2	S509	Q507L	507	Missense	proximal	-2	no	7.861	8.204	EPSD	GDSC;CCLE	8.148	Gain
CMGC_CDK_CDK2_CDK2_ST	P24941	CDK2	P24941	CDK2	T160	P155L	155	Missense	distal	-5	no	12.187	12.199	PhosphoSitePlus	GDSC;CCLE	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	P24941	CDK2	P24941	CDK2	T221	D223G	223	Missense	proximal	2	no	15.212	15.332	EPSD	GDSC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	Q14980	NUMA1	P24941	CDK2	S77	P75T	75	Missense	proximal	-2	no	10.824	10.790	EPSD	GDSC;CCLE	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	Q14980	NUMA1	P24941	CDK2	S112	M108I	108	Missense	distal	-4	no	11.332	11.930	EPSD	GDSC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	Q14980	NUMA1	P24941	CDK2	S169	A175V	175	Missense	distal	6	no	9.491	9.493	EPSD	GDSC;CCLE	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	Q14980	NUMA1	P24941	CDK2	S172	A175V	175	Missense	distal	3	no	7.636	8.757	EPSD	GDSC;CCLE	8.148	Gain
CMGC_CDK_CDK2_CDK2_ST	Q14980	NUMA1	P24941	CDK2	T1733	I1737V	1737	Missense	distal	4	no	11.679	11.935	EPSD	GDSC;CCLE	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	Q14980	NUMA1	P24941	CDK2	S1789	L1790P	1790	Missense	proximal	1	no	2.267	12.088	EPSD	GDSC;CCLE	8.148	Gain
CMGC_CDK_CDK2_CDK2_ST	Q14980	NUMA1	P24941	CDK2	S1800	D1795N	1795	Missense	distal	-5	no	11.818	11.779	EPSD	GDSC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	Q14980	NUMA1	P24941	CDK2	S1800	G1801S	1801	Missense	proximal	1	no	11.818	7.864	EPSD	GDSC	8.148	Loss
CMGC_CDK_CDK2_CDK2_ST	Q14980	NUMA1	P24941	CDK2	T2000	A2006V	2006	Missense	distal	6	no	13.794	13.797	EPSD	GDSC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	Q14980	NUMA1	P24941	CDK2	T2015	R2012C	2012	Missense	distal	-3	no	12.993	12.908	EPSD	GDSC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	Q14980	NUMA1	P24941	CDK2	T2015	F2010S	2010	Missense	distal	-5	no	12.993	12.877	EPSD	GDSC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	Q14980	NUMA1	P24941	CDK2	T2055	M2048I	2048	Missense	distal	-7	no	14.354	14.047	EPSD	GDSC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	Q14980	NUMA1	P24941	CDK2	S2077	S2077P	2077	Missense	central	0	yes	11.730	0.000	EPSD	GDSC	8.148	Loss
CMGC_CDK_CDK2_CDK2_ST	Q14980	NUMA1	P24941	CDK2	S2077	S2082R	2082	Missense	distal	5	no	11.730	11.937	EPSD	GDSC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	Q14980	NUMA1	P24941	CDK2	S2077	S2077Y	2077	Missense	central	0	yes	11.730	0.000	EPSD	GDSC	8.148	Loss
CMGC_CDK_CDK2_CDK2_ST	Q14980	NUMA1	P24941	CDK2	S2087	T2093P	2093	Missense	distal	6	no	12.911	12.903	EPSD	GDSC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	Q14980	NUMA1	P24941	CDK2	S2087	T2092P	2092	Missense	distal	5	no	12.911	12.936	EPSD	GDSC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	Q14980	NUMA1	P24941	CDK2	S2087	S2082R	2082	Missense	distal	-5	no	12.911	13.002	EPSD	GDSC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	Q14980	NUMA1	P24941	CDK2	S2087	A2091G	2091	Missense	distal	4	no	12.911	12.751	EPSD	GDSC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	Q14980	NUMA1	P24941	CDK2	T2092	T2093P	2093	Missense	proximal	1	no	1.278	11.236	EPSD	GDSC	8.148	Gain
CMGC_CDK_CDK2_CDK2_ST	Q15717	ELAVL1	P24941	CDK2	S202	S197L	197	Missense	distal	-5	no	15.691	15.747	PhosphoSitePlus	GDSC;CCLE	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	P24864	CCNE1	P24941	CDK2	S90	T91M	91	Missense	proximal	1	no	8.750	-8.105	EPSD	GDSC;CCLE	8.148	Loss
CMGC_CDK_CDK2_CDK2_ST	P24864	CCNE1	P24941	CDK2	S90	R95L	95	Missense	distal	5	no	8.750	8.684	EPSD	GDSC;CCLE	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	P24864	CCNE1	P24941	CDK2	S103	S100C	100	Missense	distal	-3	no	16.109	16.116	EPSD	GDSC;CCLE	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	P24864	CCNE1	P24941	CDK2	S387	L394P	394	Missense	distal	7	no	13.244	13.214	EPSD;PhosphoSitePlus	GDSC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	P24864	CCNE1	P24941	CDK2	T395	L394P	394	Missense	proximal	-1	no	13.881	14.061	PhosphoSitePlus;EPSD	GDSC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	P24864	CCNE1	P24941	CDK2	S399	L394P	394	Missense	distal	-5	no	10.890	10.878	EPSD;PhosphoSitePlus	GDSC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	Q14103	HNRNPD	P24941	CDK2	S83	S87T	87	Missense	distal	4	no	14.213	14.483	EPSD	GDSC;CCLE	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	Q14103	HNRNPD	P24941	CDK2	S83	H86P	86	Missense	distal	3	no	14.213	13.191	EPSD	GDSC;CCLE	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	P31350	RRM2	P24941	CDK2	S20	L27F	27	Missense	distal	7	no	16.245	16.917	EPSD;PhosphoSitePlus	GDSC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	P31350	RRM2	P24941	CDK2	T33	L27F	27	Missense	distal	-6	no	12.401	12.405	PhosphoSitePlus;EPSD	GDSC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	P16949	STMN1	P24941	CDK2	S38	P36T	36	Missense	proximal	-2	no	17.348	17.315	EPSD;PhosphoSitePlus	GDSC;CCLE	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	P12956	XRCC6	P24941	CDK2	T428	G431D	431	Missense	distal	3	no	13.162	11.450	EPSD	GDSC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	P52948	NUP98	P24941	CDK2	S231	L227F	227	Missense	distal	-4	no	11.843	11.294	EPSD	GDSC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	P52948	NUP98	P24941	CDK2	S231	S230A	230	Missense	proximal	-1	no	11.843	12.044	EPSD	GDSC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	P52948	NUP98	P24941	CDK2	S839	S839*	839	Missense	central	0	yes	15.080	0.000	EPSD	GDSC	8.148	Loss
CMGC_CDK_CDK2_CDK2_ST	P52948	NUP98	P24941	CDK2	S1689	I1683T	1683	Missense	distal	-6	no	9.421	9.419	EPSD	GDSC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	P62913	RPL11	P24941	CDK2	S29	L33P	33	Missense	distal	4	no	10.080	9.968	EPSD	GDSC;CCLE	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	Q9C0C2	TNKS1BP1	P24941	CDK2	S14	S14F	14	Missense	central	0	yes	9.834	0.000	EPSD	GDSC	8.148	Loss
CMGC_CDK_CDK2_CDK2_ST	Q9C0C2	TNKS1BP1	P24941	CDK2	S14	M12I	12	Missense	proximal	-2	no	9.834	11.765	EPSD	GDSC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	Q9C0C2	TNKS1BP1	P24941	CDK2	S178	R172Q	172	Missense	distal	-6	no	15.991	15.992	EPSD	GDSC;CCLE	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	Q9C0C2	TNKS1BP1	P24941	CDK2	S494	V489A	489	Missense	distal	-5	no	13.077	13.071	EPSD	GDSC;CCLE	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	Q9C0C2	TNKS1BP1	P24941	CDK2	S494	R491Q	491	Missense	distal	-3	no	13.077	12.947	EPSD	GDSC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	Q9C0C2	TNKS1BP1	P24941	CDK2	S498	R491Q	491	Missense	distal	-7	no	15.064	14.677	EPSD	GDSC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	Q9C0C2	TNKS1BP1	P24941	CDK2	T578	T575A	575	Missense	distal	-3	no	12.772	12.753	EPSD	GDSC;CCLE	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	Q9C0C2	TNKS1BP1	P24941	CDK2	S672	Q666P	666	Missense	distal	-6	no	10.728	10.725	EPSD	GDSC;CCLE	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	Q9C0C2	TNKS1BP1	P24941	CDK2	S730	G736R	736	Missense	distal	6	no	8.276	8.271	EPSD	GDSC;CCLE	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	Q9C0C2	TNKS1BP1	P24941	CDK2	S744	P740T	740	Missense	distal	-4	no	15.761	15.928	EPSD	GDSC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	Q9C0C2	TNKS1BP1	P24941	CDK2	S936	R943G	943	Missense	distal	7	no	8.067	8.247	EPSD	GDSC	8.148	Gain
CMGC_CDK_CDK2_CDK2_ST	Q9C0C2	TNKS1BP1	P24941	CDK2	S942	R943G	943	Missense	proximal	1	no	5.943	8.429	EPSD	GDSC	8.148	Gain
CMGC_CDK_CDK2_CDK2_ST	Q9C0C2	TNKS1BP1	P24941	CDK2	S1138	P1139L	1139	Missense	proximal	1	no	16.195	6.374	EPSD	GDSC;CCLE	8.148	Loss
CMGC_CDK_CDK2_CDK2_ST	Q9C0C2	TNKS1BP1	P24941	CDK2	S1261	E1264V	1264	Missense	distal	3	no	10.663	10.649	EPSD	GDSC;CCLE	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	Q9C0C2	TNKS1BP1	P24941	CDK2	S1439	P1444S	1444	Missense	distal	5	no	16.146	16.045	EPSD	GDSC;CCLE	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	Q9C0C2	TNKS1BP1	P24941	CDK2	S1439	S1435G	1435	Missense	distal	-4	no	16.146	15.473	EPSD	GDSC;CCLE	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	Q9C0C2	TNKS1BP1	P24941	CDK2	S1503	S1503F	1503	Missense	central	0	yes	11.873	0.000	EPSD	GDSC;CCLE	8.148	Loss
CMGC_CDK_CDK2_CDK2_ST	Q9C0C2	TNKS1BP1	P24941	CDK2	S1715	G1710V	1710	Missense	distal	-5	no	12.430	12.381	EPSD	GDSC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	Q9C0C2	TNKS1BP1	P24941	CDK2	S1715	S1715L	1715	Missense	central	0	yes	12.430	0.000	EPSD	GDSC;CCLE	8.148	Loss
CMGC_CDK_CDK2_CDK2_ST	Q14247	CTTN	P24941	CDK2	S405	Q409K	409	Missense	distal	4	no	14.637	14.977	PhosphoSitePlus	GDSC;CCLE	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	P31749	AKT1	P24941	CDK2	T312	K307N	307	Missense	distal	-5	no	15.064	15.081	EPSD	GDSC;CCLE	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	P82970	HMGN5	P24941	CDK2	T31	L27F	27	Missense	distal	-4	no	15.847	15.297	PhosphoSitePlus	GDSC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	Q9H8Y8	GORASP2	P24941	CDK2	S245	G248E	248	Missense	distal	3	no	13.398	14.121	EPSD	GDSC;CCLE	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	Q9H8Y8	GORASP2	P24941	CDK2	T433	P434A	434	Missense	proximal	1	no	15.225	0.822	EPSD	GDSC;CCLE	8.148	Loss
CMGC_CDK_CDK2_CDK2_ST	Q9Y253	POLH	P24941	CDK2	S687	T692S	692	Missense	distal	5	no	13.920	13.845	PhosphoSitePlus	GDSC;CCLE	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	P25054	APC	P24941	CDK2	S111	M115V	115	Missense	distal	4	no	16.473	17.121	EPSD	GDSC;CCLE	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	P25054	APC	P24941	CDK2	S306	R302*	302	Missense	distal	-4	no	8.301	7.811	EPSD	GDSC	8.148	Loss
CMGC_CDK_CDK2_CDK2_ST	P25054	APC	P24941	CDK2	T1023	E1020K	1020	Missense	distal	-3	no	11.779	11.563	EPSD	GDSC;CCLE	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	P25054	APC	P24941	CDK2	S1100	Q1096*	1096	Missense	distal	-4	no	16.142	15.627	EPSD	GDSC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	P25054	APC	P24941	CDK2	T1220	S1213P	1213	Missense	distal	-7	no	11.148	11.328	EPSD	GDSC;CCLE	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	P25054	APC	P24941	CDK2	T1220	A1225S	1225	Missense	distal	5	no	11.148	11.037	EPSD	GDSC;CCLE	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	P25054	APC	P24941	CDK2	T1220	E1216K	1216	Missense	distal	-4	no	11.148	10.837	EPSD	GDSC;CCLE	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	P25054	APC	P24941	CDK2	T1267	Q1260*	1260	Missense	distal	-7	no	7.722	8.240	EPSD	GDSC	8.148	Gain
CMGC_CDK_CDK2_CDK2_ST	P25054	APC	P24941	CDK2	T1267	C1270R	1270	Missense	distal	3	no	7.722	14.087	EPSD	GDSC;CCLE	8.148	Gain
CMGC_CDK_CDK2_CDK2_ST	P25054	APC	P24941	CDK2	S1360	Q1367*	1367	Missense	distal	7	no	16.350	16.933	PhosphoSitePlus	GDSC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	P25054	APC	P24941	CDK2	T1368	Q1367*	1367	Missense	proximal	-1	no	14.571	15.780	EPSD	GDSC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	P25054	APC	P24941	CDK2	S1371	Q1367*	1367	Missense	distal	-4	no	11.727	11.212	EPSD	GDSC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	P25054	APC	P24941	CDK2	S1426	Q1429*	1429	Missense	distal	3	no	13.446	14.736	EPSD	GDSC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	P25054	APC	P24941	CDK2	S1465	K1462*	1462	Missense	distal	-3	no	9.874	10.234	EPSD	GDSC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	P25054	APC	P24941	CDK2	T1633	D1636Y	1636	Missense	distal	3	no	13.131	14.199	EPSD	GDSC;CCLE	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	P25054	APC	P24941	CDK2	S1681	R1687*	1687	Missense	distal	6	no	9.118	9.117	EPSD	GDSC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	P25054	APC	P24941	CDK2	S1995	Q1996H	1996	Missense	proximal	1	no	7.515	8.668	EPSD	GDSC;CCLE	8.148	Gain
CMGC_CDK_CDK2_CDK2_ST	P25054	APC	P24941	CDK2	S2064	G2070D	2070	Missense	distal	6	no	12.880	12.876	EPSD	GDSC;CCLE	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	P25054	APC	P24941	CDK2	S2146	G2145V	2145	Missense	proximal	-1	no	16.096	15.004	EPSD	GDSC;CCLE	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	P25054	APC	P24941	CDK2	S2146	L2150V	2150	Missense	distal	4	no	16.096	16.211	EPSD	GDSC;CCLE	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	P25054	APC	P24941	CDK2	T2151	L2150V	2150	Missense	proximal	-1	no	12.566	12.703	EPSD	GDSC;CCLE	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	P25054	APC	P24941	CDK2	S2244	K2248*	2248	Missense	distal	4	no	13.417	12.641	EPSD	GDSC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	P25054	APC	P24941	CDK2	T2255	K2248*	2248	Missense	distal	-7	no	11.583	12.105	EPSD	GDSC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	P25054	APC	P24941	CDK2	T2255	S2262N	2262	Missense	distal	7	no	11.583	11.641	EPSD	GDSC;CCLE	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	P25054	APC	P24941	CDK2	S2260	S2262N	2262	Missense	proximal	2	no	13.997	13.860	EPSD	GDSC;CCLE	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	P25054	APC	P24941	CDK2	S2330	R2333K	2333	Missense	distal	3	no	11.612	12.601	EPSD	GDSC;CCLE	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	P25054	APC	P24941	CDK2	S2337	L2342F	2342	Missense	distal	5	no	12.341	12.518	EPSD	GDSC;CCLE	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	P25054	APC	P24941	CDK2	S2337	R2333K	2333	Missense	distal	-4	no	12.341	12.503	EPSD	GDSC;CCLE	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	P25054	APC	P24941	CDK2	S2449	P2448S	2448	Missense	proximal	-1	no	14.181	13.710	EPSD	GDSC;CCLE	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	P25054	APC	P24941	CDK2	S2466	F2462S	2462	Missense	distal	-4	no	11.045	12.007	EPSD	GDSC;CCLE	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	P25054	APC	P24941	CDK2	S2466	P2467L	2467	Missense	proximal	1	no	11.045	1.224	EPSD	GDSC;CCLE	8.148	Loss
CMGC_CDK_CDK2_CDK2_ST	P25054	APC	P24941	CDK2	S2512	R2505G	2505	Missense	distal	-7	no	12.667	12.648	EPSD	GDSC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	P25054	APC	P24941	CDK2	S2621	S2625I	2625	Missense	distal	4	no	11.510	11.468	EPSD	GDSC;CCLE	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	P25054	APC	P24941	CDK2	S2621	E2617V	2617	Missense	distal	-4	no	11.510	11.232	EPSD	GDSC;CCLE	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	P25054	APC	P24941	CDK2	S2674	R2673G	2673	Missense	proximal	-1	no	10.985	11.463	EPSD	GDSC;CCLE	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	P25054	APC	P24941	CDK2	T2679	V2686A	2686	Missense	distal	7	no	14.248	14.374	EPSD	GDSC;CCLE	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	P25054	APC	P24941	CDK2	S2772	A2778V	2778	Missense	distal	6	no	10.099	10.101	EPSD	GDSC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	P25054	APC	P24941	CDK2	T2782	A2778V	2778	Missense	distal	-4	no	11.635	11.646	EPSD	GDSC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	P25054	APC	P24941	CDK2	S2830	H2834Y	2834	Missense	distal	4	no	15.826	16.263	EPSD	GDSC;CCLE	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	Q99626	CDX2	P24941	CDK2	S283	V285M	285	Missense	proximal	2	no	15.969	16.058	PhosphoSitePlus	GDSC;CCLE	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	Q13118	KLF10	P24941	CDK2	T93	L92F	92	Missense	proximal	-1	no	11.657	12.622	EPSD	GDSC;CCLE	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	Q13118	KLF10	P24941	CDK2	S97	L92F	92	Missense	distal	-5	no	13.807	13.867	EPSD	GDSC;CCLE	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	Q13118	KLF10	P24941	CDK2	S206	A203V	203	Missense	distal	-3	no	14.452	14.653	PhosphoSitePlus	GDSC;CCLE	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	Q13118	KLF10	P24941	CDK2	T358	Q360E	360	Missense	proximal	2	no	10.913	10.951	EPSD	GDSC;CCLE	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	Q13118	KLF10	P24941	CDK2	S384	T390M	390	Missense	distal	6	no	9.740	9.714	EPSD	GDSC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	Q13118	KLF10	P24941	CDK2	T394	T390M	390	Missense	distal	-4	no	8.999	8.084	EPSD	GDSC	8.148	Loss
CMGC_CDK_CDK2_CDK2_ST	Q13118	KLF10	P24941	CDK2	T424	F429C	429	Missense	distal	5	no	10.361	10.378	EPSD	GDSC;CCLE	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	Q9C0C9	UBE2O	P24941	CDK2	S401	R396W	396	Missense	distal	-5	no	15.375	15.462	EPSD	GDSC;CCLE	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	P23258	TUBG1	P24941	CDK2	S32	E34K	34	Missense	proximal	2	no	11.518	11.281	EPSD	GDSC;CCLE	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	P23258	TUBG1	P24941	CDK2	S80	A83T	83	Missense	distal	3	no	15.010	15.407	PhosphoSitePlus	GDSC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	Q9ULW0	TPX2	P24941	CDK2	T338	V331A	331	Missense	distal	-7	no	15.150	15.295	EPSD	GDSC;CCLE	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	Q9ULW0	TPX2	P24941	CDK2	T369	C364F	364	Missense	distal	-5	no	11.771	11.763	EPSD	GDSC;CCLE	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	O14686	KMT2D	P24941	CDK2	T54	Q56*	56	Missense	proximal	2	no	9.652	9.766	EPSD	GDSC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	O14686	KMT2D	P24941	CDK2	T54	S59N	59	Missense	distal	5	no	9.652	9.856	EPSD	GDSC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	O14686	KMT2D	P24941	CDK2	S98	R93Q	93	Missense	distal	-5	no	13.562	13.515	EPSD	GDSC;CCLE	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	O14686	KMT2D	P24941	CDK2	S468	S465*	465	Missense	distal	-3	no	13.541	13.765	EPSD	GDSC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	O14686	KMT2D	P24941	CDK2	S591	S597F	597	Missense	distal	6	no	14.123	14.104	EPSD	GDSC;CCLE	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	O14686	KMT2D	P24941	CDK2	S618	R625H	625	Missense	distal	7	no	13.691	13.332	EPSD	GDSC;CCLE	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	O14686	KMT2D	P24941	CDK2	S627	R625H	625	Missense	proximal	-2	no	12.679	12.905	EPSD	GDSC;CCLE	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	O14686	KMT2D	P24941	CDK2	S654	S651L	651	Missense	distal	-3	no	11.205	11.039	EPSD	GDSC;CCLE	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	O14686	KMT2D	P24941	CDK2	S663	L662Q	662	Missense	proximal	-1	no	11.009	10.881	EPSD	GDSC;CCLE	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	O14686	KMT2D	P24941	CDK2	S669	S672F	672	Missense	distal	3	no	12.383	12.307	EPSD	GDSC;CCLE	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	O14686	KMT2D	P24941	CDK2	S669	L662Q	662	Missense	distal	-7	no	12.383	12.334	EPSD	GDSC;CCLE	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	O14686	KMT2D	P24941	CDK2	S672	S672F	672	Missense	central	0	yes	12.318	0.000	EPSD	GDSC;CCLE	8.148	Loss
CMGC_CDK_CDK2_CDK2_ST	O14686	KMT2D	P24941	CDK2	S678	S672F	672	Missense	distal	-6	no	12.374	12.379	EPSD	GDSC;CCLE	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	O14686	KMT2D	P24941	CDK2	S681	R688H	688	Missense	distal	7	no	12.996	12.638	EPSD	GDSC;CCLE	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	O14686	KMT2D	P24941	CDK2	S744	R746Q	746	Missense	proximal	2	no	12.383	12.283	EPSD	GDSC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	O14686	KMT2D	P24941	CDK2	S744	E749G	749	Missense	distal	5	no	12.383	12.431	EPSD	GDSC;CCLE	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	O14686	KMT2D	P24941	CDK2	S753	E758*	758	Missense	distal	5	no	12.827	12.944	EPSD	GDSC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	O14686	KMT2D	P24941	CDK2	S753	R746Q	746	Missense	distal	-7	no	12.827	12.441	EPSD	GDSC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	O14686	KMT2D	P24941	CDK2	S753	E749G	749	Missense	distal	-4	no	12.827	12.279	EPSD	GDSC;CCLE	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	O14686	KMT2D	P24941	CDK2	S753	P759L	759	Missense	distal	6	no	12.827	12.828	EPSD	GDSC;CCLE	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	O14686	KMT2D	P24941	CDK2	S753	P759S	759	Missense	distal	6	no	12.827	12.828	EPSD	GDSC;CCLE	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	O14686	KMT2D	P24941	CDK2	S753	S753P	753	Missense	central	0	yes	12.827	0.000	EPSD	GDSC	8.148	Loss
CMGC_CDK_CDK2_CDK2_ST	O14686	KMT2D	P24941	CDK2	S762	E758*	758	Missense	distal	-4	no	12.215	11.251	EPSD	GDSC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	O14686	KMT2D	P24941	CDK2	S762	P759L	759	Missense	distal	-3	no	12.215	12.143	EPSD	GDSC;CCLE	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	O14686	KMT2D	P24941	CDK2	S762	P759S	759	Missense	distal	-3	no	12.215	12.310	EPSD	GDSC;CCLE	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	O14686	KMT2D	P24941	CDK2	S952	G955R	955	Missense	distal	3	no	13.678	15.497	EPSD	GDSC;CCLE	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	O14686	KMT2D	P24941	CDK2	S1146	Q1139K	1139	Missense	distal	-7	no	8.404	8.399	EPSD	GDSC;CCLE	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	O14686	KMT2D	P24941	CDK2	T1164	M1166V	1166	Missense	proximal	2	no	13.764	13.675	EPSD	GDSC;CCLE	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	O14686	KMT2D	P24941	CDK2	T1164	T1164I	1164	Missense	central	0	yes	13.764	0.000	EPSD	GDSC;CCLE	8.148	Loss
CMGC_CDK_CDK2_CDK2_ST	O14686	KMT2D	P24941	CDK2	T1195	A1193S	1193	Missense	proximal	-2	no	14.225	13.557	EPSD	GDSC;CCLE	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	O14686	KMT2D	P24941	CDK2	T1195	P1188S	1188	Missense	distal	-7	no	14.225	14.045	EPSD	GDSC;CCLE	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	O14686	KMT2D	P24941	CDK2	S1249	R1252*	1252	Missense	distal	3	no	16.439	15.985	EPSD	GDSC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	O14686	KMT2D	P24941	CDK2	S1606	L1599V	1599	Missense	distal	-7	no	16.246	16.260	EPSD	GDSC;CCLE	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	O14686	KMT2D	P24941	CDK2	T1843	E1847D	1847	Missense	distal	4	no	16.149	16.067	EPSD	GDSC;CCLE	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	O14686	KMT2D	P24941	CDK2	S1854	E1847D	1847	Missense	distal	-7	no	15.691	15.842	EPSD	GDSC;CCLE	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	O14686	KMT2D	P24941	CDK2	S1854	P1860H	1860	Missense	distal	6	no	15.691	15.686	EPSD	GDSC;CCLE	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	O14686	KMT2D	P24941	CDK2	T1865	P1860H	1860	Missense	distal	-5	no	16.932	16.979	EPSD	GDSC;CCLE	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	O14686	KMT2D	P24941	CDK2	S2274	P2275S	2275	Missense	proximal	1	no	12.104	0.838	EPSD	GDSC;CCLE	8.148	Loss
CMGC_CDK_CDK2_CDK2_ST	O14686	KMT2D	P24941	CDK2	T2332	Q2337K	2337	Missense	distal	5	no	11.648	11.634	EPSD	GDSC;CCLE	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	O14686	KMT2D	P24941	CDK2	S2342	Q2337K	2337	Missense	distal	-5	no	14.397	14.399	EPSD	GDSC;CCLE	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	O14686	KMT2D	P24941	CDK2	S2414	R2410*	2410	Missense	distal	-4	no	12.864	12.375	EPSD	GDSC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	O14686	KMT2D	P24941	CDK2	S2446	R2452S	2452	Missense	distal	6	no	11.826	11.843	EPSD	GDSC;CCLE	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	O14686	KMT2D	P24941	CDK2	S2446	S2451F	2451	Missense	distal	5	no	11.826	12.144	EPSD	GDSC;CCLE	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	O14686	KMT2D	P24941	CDK2	S2608	S2614*	2614	Missense	distal	6	no	14.981	14.963	EPSD	GDSC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	O14686	KMT2D	P24941	CDK2	S2608	R2611H	2611	Missense	distal	3	no	14.981	14.285	EPSD	GDSC;CCLE	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	O14686	KMT2D	P24941	CDK2	S2636	R2635*	2635	Missense	proximal	-1	no	9.649	9.980	EPSD	GDSC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	O14686	KMT2D	P24941	CDK2	S2636	P2641H	2641	Missense	distal	5	no	9.649	9.727	EPSD	GDSC;CCLE	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	O14686	KMT2D	P24941	CDK2	S2640	R2635*	2635	Missense	distal	-5	no	16.077	16.120	EPSD	GDSC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	O14686	KMT2D	P24941	CDK2	S2640	P2641H	2641	Missense	proximal	1	no	16.077	9.318	EPSD	GDSC;CCLE	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	O14686	KMT2D	P24941	CDK2	T2664	S2670C	2670	Missense	distal	6	no	8.390	8.375	EPSD	GDSC;CCLE	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	O14686	KMT2D	P24941	CDK2	T2737	Q2736*	2736	Missense	proximal	-1	no	13.241	14.450	EPSD	GDSC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	O14686	KMT2D	P24941	CDK2	T2742	Q2736*	2736	Missense	distal	-6	no	9.069	9.074	EPSD	GDSC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	O14686	KMT2D	P24941	CDK2	S2852	G2846C	2846	Missense	distal	-6	no	15.356	15.359	EPSD	GDSC;CCLE	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	O14686	KMT2D	P24941	CDK2	S3620	V3616A	3616	Missense	distal	-4	no	13.898	13.887	EPSD	GDSC;CCLE	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	O14686	KMT2D	P24941	CDK2	S3837	V3834A	3834	Missense	distal	-3	no	13.020	12.819	EPSD	GDSC;CCLE	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	O14686	KMT2D	P24941	CDK2	T4308	V4305I	4305	Missense	distal	-3	no	11.652	11.529	EPSD	GDSC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	O14686	KMT2D	P24941	CDK2	T4308	Q4315E	4315	Missense	distal	7	no	11.652	11.851	EPSD	GDSC;CCLE	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	O14686	KMT2D	P24941	CDK2	S4313	Q4315E	4315	Missense	proximal	2	no	14.715	14.753	EPSD	GDSC;CCLE	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	O14686	KMT2D	P24941	CDK2	T4476	G4479R	4479	Missense	distal	3	no	7.075	8.894	EPSD	GDSC;CCLE	8.148	Gain
CMGC_CDK_CDK2_CDK2_ST	O14686	KMT2D	P24941	CDK2	T4621	P4628L	4628	Missense	distal	7	no	14.941	14.972	EPSD	GDSC;CCLE	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	O14686	KMT2D	P24941	CDK2	T4629	P4628L	4628	Missense	proximal	-1	no	12.910	12.731	EPSD	GDSC;CCLE	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	O14686	KMT2D	P24941	CDK2	T4643	E4646*	4646	Missense	distal	3	no	13.882	14.525	EPSD	GDSC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	O14686	KMT2D	P24941	CDK2	S4710	E4712*	4712	Missense	proximal	2	no	13.178	13.254	EPSD	GDSC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	O14686	KMT2D	P24941	CDK2	S4738	E4731Q	4731	Missense	distal	-7	no	14.964	14.831	EPSD	GDSC;CCLE	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	O14686	KMT2D	P24941	CDK2	S4955	R4960*	4960	Missense	distal	5	no	13.119	13.209	EPSD	GDSC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	O14686	KMT2D	P24941	CDK2	T5374	Q5379R	5379	Missense	distal	5	no	15.651	15.797	PhosphoSitePlus	GDSC;CCLE	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	P29590	PML	P24941	CDK2	S221	A216P	216	Missense	distal	-5	no	8.287	8.262	EPSD	GDSC;CCLE	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	P29590	PML	P24941	CDK2	T391	S388T	388	Missense	distal	-3	no	9.259	9.124	EPSD	GDSC;CCLE	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	P29590	PML	P24941	CDK2	S527	P526T	526	Missense	proximal	-1	no	15.309	15.046	EPSD	GDSC;CCLE	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	P29590	PML	P24941	CDK2	S527	V532I	532	Missense	distal	5	no	15.309	15.435	EPSD	GDSC;CCLE	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	P29590	PML	P24941	CDK2	S530	P526T	526	Missense	distal	-4	no	14.428	14.594	EPSD	GDSC;CCLE	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	P29590	PML	P24941	CDK2	S530	V532I	532	Missense	proximal	2	no	14.428	14.283	EPSD	GDSC;CCLE	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	P29590	PML	P24941	CDK2	T867	R861Q	861	Missense	distal	-6	no	12.361	12.362	EPSD	GDSC;CCLE	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	P29590	PML	P24941	CDK2	T867	L869R	869	Missense	proximal	2	no	12.361	12.627	EPSD	GDSC;CCLE	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	Q13242	SRSF9	P24941	CDK2	S197	Y192*	192	Missense	distal	-5	no	9.099	9.165	EPSD	GDSC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	Q13242	SRSF9	P24941	CDK2	S211	F215Y	215	Missense	distal	4	no	14.174	14.555	EPSD	GDSC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	Q13242	SRSF9	P24941	CDK2	S211	Y214C	214	Missense	distal	3	no	14.174	10.273	EPSD	GDSC;CCLE	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	Q13242	SRSF9	P24941	CDK2	S216	F215Y	215	Missense	proximal	-1	no	17.779	17.432	PhosphoSitePlus	GDSC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	Q13242	SRSF9	P24941	CDK2	S216	Y214C	214	Missense	proximal	-2	no	17.779	17.282	PhosphoSitePlus	GDSC;CCLE	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	Q05682	CALD1	P24941	CDK2	T753	N757S	757	Missense	distal	4	no	12.631	12.664	EPSD	GDSC;CCLE	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	Q05682	CALD1	P24941	CDK2	S759	P764L	764	Missense	distal	5	no	13.252	13.291	EPSD	GDSC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	Q05682	CALD1	P24941	CDK2	S759	S765T	765	Missense	distal	6	no	13.252	13.258	EPSD	GDSC;CCLE	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	Q05682	CALD1	P24941	CDK2	S759	N757S	757	Missense	proximal	-2	no	13.252	13.943	EPSD	GDSC;CCLE	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	Q05682	CALD1	P24941	CDK2	S789	T791A	791	Missense	proximal	2	no	16.205	16.408	EPSD	GDSC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	P49916	LIG3	P24941	CDK2	T191	A189S	189	Missense	proximal	-2	no	17.328	16.660	PhosphoSitePlus;EPSD	GDSC;CCLE	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	P49916	LIG3	P24941	CDK2	T479	L485F	485	Missense	distal	6	no	16.156	16.137	EPSD	GDSC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	P48634	PRRC2A	P24941	CDK2	T116	P112T	112	Missense	distal	-4	no	10.231	10.398	EPSD	GDSC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	P48634	PRRC2A	P24941	CDK2	S380	P386L	386	Missense	distal	6	no	10.568	10.570	EPSD	GDSC;CCLE	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	P48634	PRRC2A	P24941	CDK2	T387	P386L	386	Missense	proximal	-1	no	14.116	13.937	EPSD	GDSC;CCLE	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	P48634	PRRC2A	P24941	CDK2	T517	P511Q	511	Missense	distal	-6	no	12.943	12.946	EPSD	GDSC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	P48634	PRRC2A	P24941	CDK2	T517	P511A	511	Missense	distal	-6	no	12.943	12.942	EPSD	GDSC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	P48634	PRRC2A	P24941	CDK2	T517	V524I	524	Missense	distal	7	no	12.943	12.742	EPSD	GDSC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	P48634	PRRC2A	P24941	CDK2	T517	P518L	518	Missense	proximal	1	no	12.943	3.123	EPSD	GDSC;CCLE	8.148	Loss
CMGC_CDK_CDK2_CDK2_ST	P48634	PRRC2A	P24941	CDK2	T675	V677M	677	Missense	proximal	2	no	12.266	12.354	EPSD	GDSC;CCLE	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	P48634	PRRC2A	P24941	CDK2	S680	V677M	677	Missense	distal	-3	no	10.643	10.869	EPSD	GDSC;CCLE	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	P48634	PRRC2A	P24941	CDK2	S680	L687R	687	Missense	distal	7	no	10.643	11.103	EPSD	GDSC;CCLE	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	P48634	PRRC2A	P24941	CDK2	S761	R756*	756	Missense	distal	-5	no	8.111	8.155	EPSD	GDSC	8.148	Gain
CMGC_CDK_CDK2_CDK2_ST	P48634	PRRC2A	P24941	CDK2	T782	R778W	778	Missense	distal	-4	no	13.246	12.489	EPSD	GDSC;CCLE	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	P48634	PRRC2A	P24941	CDK2	T799	A798T	798	Missense	proximal	-1	no	14.750	14.757	EPSD	GDSC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	P48634	PRRC2A	P24941	CDK2	T799	P800S	800	Missense	proximal	1	no	14.750	3.484	EPSD	GDSC;CCLE	8.148	Loss
CMGC_CDK_CDK2_CDK2_ST	P48634	PRRC2A	P24941	CDK2	T825	P827Q	827	Missense	proximal	2	no	15.990	16.049	EPSD	GDSC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	P48634	PRRC2A	P24941	CDK2	T878	P881L	881	Missense	distal	3	no	15.249	14.865	EPSD	GDSC;CCLE	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	P48634	PRRC2A	P24941	CDK2	T997	N1000H	1000	Missense	distal	3	no	12.624	14.208	EPSD	GDSC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	P48634	PRRC2A	P24941	CDK2	S1004	N1000H	1000	Missense	distal	-4	no	15.107	14.365	EPSD	GDSC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	P48634	PRRC2A	P24941	CDK2	T1108	R1101C	1101	Missense	distal	-7	no	9.643	9.570	EPSD	GDSC;CCLE	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	P48634	PRRC2A	P24941	CDK2	S1147	A1151V	1151	Missense	distal	4	no	12.992	13.180	EPSD	GDSC;CCLE	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	P48634	PRRC2A	P24941	CDK2	S1186	P1179T	1179	Missense	distal	-7	no	12.590	12.587	EPSD	GDSC;CCLE	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	P48634	PRRC2A	P24941	CDK2	S1186	P1179H	1179	Missense	distal	-7	no	12.590	12.713	EPSD	GDSC;CCLE	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	P48634	PRRC2A	P24941	CDK2	S1186	A1193S	1193	Missense	distal	7	no	12.590	12.053	EPSD	GDSC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	P48634	PRRC2A	P24941	CDK2	S1186	P1187S	1187	Missense	proximal	1	no	12.590	1.324	EPSD	GDSC;CCLE	8.148	Loss
CMGC_CDK_CDK2_CDK2_ST	P48634	PRRC2A	P24941	CDK2	S1219	P1215Q	1215	Missense	distal	-4	no	14.344	14.125	EPSD	GDSC;CCLE	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	P48634	PRRC2A	P24941	CDK2	S1219	A1222T	1222	Missense	distal	3	no	14.344	14.741	EPSD	GDSC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	P48634	PRRC2A	P24941	CDK2	S1306	P1299T	1299	Missense	distal	-7	no	14.241	14.239	EPSD	GDSC;CCLE	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	P48634	PRRC2A	P24941	CDK2	S1306	D1308Y	1308	Missense	proximal	2	no	14.241	14.302	EPSD	GDSC;CCLE	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	P48634	PRRC2A	P24941	CDK2	S1435	P1434L	1434	Missense	proximal	-1	no	10.150	9.971	EPSD	GDSC;CCLE	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	P48634	PRRC2A	P24941	CDK2	S2036	R2032W	2032	Missense	distal	-4	no	15.988	15.231	EPSD	GDSC;CCLE	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	P48634	PRRC2A	P24941	CDK2	S2113	P2115S	2115	Missense	proximal	2	no	12.104	12.171	EPSD	GDSC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	O95251	KAT7	P24941	CDK2	S124	P125L	125	Missense	proximal	1	no	21.068	11.247	EPSD	GDSC;CCLE	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	O95251	KAT7	P24941	CDK2	T128	P125L	125	Missense	distal	-3	no	14.686	14.615	EPSD	GDSC;CCLE	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	O15014	ZNF609	P24941	CDK2	T76	G80A	80	Missense	distal	4	no	12.373	12.533	EPSD	GDSC;CCLE	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	O15014	ZNF609	P24941	CDK2	T76	G80C	80	Missense	distal	4	no	12.373	11.746	EPSD	GDSC;CCLE	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	O15014	ZNF609	P24941	CDK2	T103	T99A	99	Missense	distal	-4	no	12.980	12.754	EPSD	GDSC;CCLE	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	O15014	ZNF609	P24941	CDK2	T103	T110S	110	Missense	distal	7	no	12.980	13.132	EPSD	GDSC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	O15014	ZNF609	P24941	CDK2	T103	K101T	101	Missense	proximal	-2	no	12.980	13.461	EPSD	GDSC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	O15014	ZNF609	P24941	CDK2	S252	E251*	251	Missense	proximal	-1	no	11.772	11.889	EPSD	GDSC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	O15014	ZNF609	P24941	CDK2	T256	E251*	251	Missense	distal	-5	no	15.112	15.164	EPSD	GDSC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	O15014	ZNF609	P24941	CDK2	T566	V572I	572	Missense	distal	6	no	14.016	14.017	EPSD	GDSC;CCLE	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	O15014	ZNF609	P24941	CDK2	T566	R570*	570	Missense	distal	4	no	14.016	13.761	EPSD	GDSC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	O15014	ZNF609	P24941	CDK2	S576	V572I	572	Missense	distal	-4	no	15.211	15.108	EPSD	GDSC;CCLE	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	O15014	ZNF609	P24941	CDK2	S576	R570*	570	Missense	distal	-6	no	15.211	15.218	EPSD	GDSC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	O15014	ZNF609	P24941	CDK2	S609	A603V	603	Missense	distal	-6	no	8.370	8.373	EPSD	GDSC;CCLE	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	O15014	ZNF609	P24941	CDK2	S680	T673A	673	Missense	distal	-7	no	12.267	12.435	EPSD	GDSC;CCLE	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	O15014	ZNF609	P24941	CDK2	T722	N718T	718	Missense	distal	-4	no	14.641	14.669	PhosphoSitePlus	GDSC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	O15014	ZNF609	P24941	CDK2	S743	E736D	736	Missense	distal	-7	no	15.898	16.049	EPSD	GDSC;CCLE	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	O15014	ZNF609	P24941	CDK2	S804	A802T	802	Missense	proximal	-2	no	13.908	13.858	EPSD	GDSC;CCLE	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	O15014	ZNF609	P24941	CDK2	T817	Q820E	820	Missense	distal	3	no	10.966	11.613	EPSD	GDSC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	O15014	ZNF609	P24941	CDK2	T823	Q820E	820	Missense	distal	-3	no	16.245	16.362	EPSD	GDSC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	O15014	ZNF609	P24941	CDK2	S889	P882S	882	Missense	distal	-7	no	12.960	12.780	EPSD	GDSC;CCLE	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	O15014	ZNF609	P24941	CDK2	S1313	K1312N	1312	Missense	proximal	-1	no	13.990	14.016	EPSD	GDSC;CCLE	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	P17706	PTPN2	P24941	CDK2	T261	L258I	258	Missense	distal	-3	no	11.726	11.816	EPSD	GDSC;CCLE	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	P17706	PTPN2	P24941	CDK2	T261	R255*	255	Missense	distal	-6	no	11.726	11.732	EPSD	GDSC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	Q9Y3Z3	SAMHD1	P24941	CDK2	T21	P26L	26	Missense	distal	5	no	14.942	14.982	EPSD	GDSC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	Q9Y3Z3	SAMHD1	P24941	CDK2	T25	P26L	26	Missense	proximal	1	no	13.338	3.517	EPSD	GDSC	8.148	Loss
CMGC_CDK_CDK2_CDK2_ST	Q9Y3Z3	SAMHD1	P24941	CDK2	S33	P26L	26	Missense	distal	-7	no	14.172	14.177	EPSD	GDSC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	Q9Y3Z3	SAMHD1	P24941	CDK2	S278	L276P	276	Missense	proximal	-2	no	14.555	14.779	EPSD	GDSC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	Q9Y3Z3	SAMHD1	P24941	CDK2	T592	D585G	585	Missense	distal	-7	no	17.916	17.999	PhosphoSitePlus	GDSC;CCLE	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	O14497	ARID1A	P24941	CDK2	S301	T300M	300	Missense	proximal	-1	no	15.027	16.340	EPSD	GDSC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	O14497	ARID1A	P24941	CDK2	S682	H684D	684	Missense	proximal	2	no	11.289	11.208	EPSD	GDSC;CCLE	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	O14497	ARID1A	P24941	CDK2	S696	R693*	693	Missense	distal	-3	no	13.124	13.254	EPSD	GDSC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	O14497	ARID1A	P24941	CDK2	S698	R693*	693	Missense	distal	-5	no	11.860	11.903	EPSD	GDSC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	O14497	ARID1A	P24941	CDK2	S772	R774C	774	Missense	proximal	2	no	13.634	13.621	EPSD	GDSC;CCLE	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	O14497	ARID1A	P24941	CDK2	S772	P776S	776	Missense	distal	4	no	13.634	13.647	EPSD	GDSC;CCLE	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	O14497	ARID1A	P24941	CDK2	S777	R774C	774	Missense	distal	-3	no	8.248	8.162	EPSD	GDSC;CCLE	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	O14497	ARID1A	P24941	CDK2	S777	P776S	776	Missense	proximal	-1	no	8.248	7.777	EPSD	GDSC;CCLE	8.148	Loss
CMGC_CDK_CDK2_CDK2_ST	O14497	ARID1A	P24941	CDK2	S964	E966K	966	Missense	proximal	2	no	14.072	13.834	EPSD	GDSC;CCLE	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	O14497	ARID1A	P24941	CDK2	S1057	V1058G	1058	Missense	proximal	1	no	-1.332	8.267	EPSD	GDSC;CCLE	8.148	Gain
CMGC_CDK_CDK2_CDK2_ST	O14497	ARID1A	P24941	CDK2	S1138	P1144T	1144	Missense	distal	6	no	8.788	8.796	EPSD	GDSC;CCLE	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	O14497	ARID1A	P24941	CDK2	T1146	P1144T	1144	Missense	proximal	-2	no	13.026	12.993	EPSD	GDSC;CCLE	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	O14497	ARID1A	P24941	CDK2	T1206	Q1212*	1212	Missense	distal	6	no	16.056	16.033	EPSD	GDSC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	O14497	ARID1A	P24941	CDK2	S1316	S1322G	1322	Missense	distal	6	no	8.789	8.777	EPSD	GDSC;CCLE	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	O14497	ARID1A	P24941	CDK2	S1320	S1322G	1322	Missense	proximal	2	no	15.061	15.112	EPSD	GDSC;CCLE	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	O14497	ARID1A	P24941	CDK2	S1755	G1761C	1761	Missense	distal	6	no	14.401	14.398	EPSD	GDSC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	O14497	ARID1A	P24941	CDK2	T1888	A1885V	1885	Missense	distal	-3	no	14.012	14.214	EPSD	GDSC;CCLE	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	O14497	ARID1A	P24941	CDK2	S1944	Q1947*	1947	Missense	distal	3	no	14.606	15.896	EPSD	GDSC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	O14497	ARID1A	P24941	CDK2	S1948	Q1947*	1947	Missense	proximal	-1	no	8.153	9.363	EPSD	GDSC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	O14497	ARID1A	P24941	CDK2	S2113	Q2115*	2115	Missense	proximal	2	no	13.433	13.547	EPSD	GDSC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	Q15910	EZH2	P24941	CDK2	T261	N268D	268	Missense	distal	7	no	12.636	13.416	EPSD	GDSC;CCLE	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	Q96T88	UHRF1	P24941	CDK2	S439	G440C	440	Missense	proximal	1	no	8.285	-3.332	EPSD	GDSC	8.148	Loss
CMGC_CDK_CDK2_CDK2_ST	Q7KZ85	SUPT6H	P24941	CDK2	S75	G72A	72	Missense	distal	-3	no	8.965	8.803	EPSD	GDSC;CCLE	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	Q7KZ85	SUPT6H	P24941	CDK2	T292	R290Q	290	Missense	proximal	-2	no	7.548	8.217	EPSD	GDSC;CCLE	8.148	Gain
CMGC_CDK_CDK2_CDK2_ST	Q7KZ85	SUPT6H	P24941	CDK2	T1523	T1530P	1530	Missense	distal	7	no	11.752	12.056	PhosphoSitePlus	GDSC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	Q7KZ85	SUPT6H	P24941	CDK2	T1532	T1539P	1539	Missense	distal	7	no	13.927	14.231	EPSD	GDSC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	Q7KZ85	SUPT6H	P24941	CDK2	T1532	T1530P	1530	Missense	proximal	-2	no	13.927	13.961	EPSD	GDSC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	Q7KZ85	SUPT6H	P24941	CDK2	T1539	T1539P	1539	Missense	central	0	yes	12.370	0.000	EPSD	GDSC	8.148	Loss
CMGC_CDK_CDK2_CDK2_ST	Q7KZ85	SUPT6H	P24941	CDK2	S1668	G1675V	1675	Missense	distal	7	no	8.551	8.140	EPSD	GDSC;CCLE	8.148	Loss
CMGC_CDK_CDK2_CDK2_ST	Q7KZ85	SUPT6H	P24941	CDK2	T1697	P1700S	1700	Missense	distal	3	no	12.430	12.464	EPSD	GDSC;CCLE	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	Q7KZ85	SUPT6H	P24941	CDK2	S1701	P1700S	1700	Missense	proximal	-1	no	14.762	14.291	EPSD	GDSC;CCLE	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	Q7KZ85	SUPT6H	P24941	CDK2	S1703	P1700S	1700	Missense	distal	-3	no	12.593	12.688	EPSD	GDSC;CCLE	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	Q12948	FOXC1	P24941	CDK2	S241	A245T	245	Missense	distal	4	no	12.910	13.153	EPSD	GDSC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	Q12948	FOXC1	P24941	CDK2	S259	A253V	253	Missense	distal	-6	no	13.897	13.900	EPSD	GDSC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	Q6UB35	MTHFD1L	P24941	CDK2	S271	E275D	275	Missense	distal	4	no	14.231	14.150	EPSD	GDSC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	Q6UB35	MTHFD1L	P24941	CDK2	S357	Q354*	354	Missense	distal	-3	no	14.360	14.621	PhosphoSitePlus	GDSC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	Q6UB35	MTHFD1L	P24941	CDK2	S885	E887*	887	Missense	proximal	2	no	14.109	14.186	EPSD	GDSC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	Q15047	SETDB1	P24941	CDK2	T144	L150I	150	Missense	distal	6	no	11.022	11.021	EPSD	GDSC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	Q15047	SETDB1	P24941	CDK2	S906	S905G	905	Missense	proximal	-1	no	8.602	10.122	EPSD	GDSC;CCLE	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	Q15047	SETDB1	P24941	CDK2	S1112	R1116Q	1116	Missense	distal	4	no	8.084	8.265	EPSD	GDSC;CCLE	8.148	Gain
CMGC_CDK_CDK2_CDK2_ST	O60934	NBN	P24941	CDK2	S343	E350G	350	Missense	distal	7	no	7.584	8.210	EPSD	GDSC;CCLE	8.148	Gain
CMGC_CDK_CDK2_CDK2_ST	O60934	NBN	P24941	CDK2	S432	I439M	439	Missense	distal	7	no	16.721	17.209	PhosphoSitePlus	GDSC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	O60934	NBN	P24941	CDK2	S462	I455M	455	Missense	distal	-7	no	8.501	8.808	EPSD	GDSC;CCLE	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	O60934	NBN	P24941	CDK2	S462	F459L	459	Missense	distal	-3	no	8.501	8.244	EPSD	GDSC;CCLE	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	Q6PKG0	LARP1	P24941	CDK2	S191	R198C	198	Missense	distal	7	no	8.480	8.631	EPSD	GDSC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	Q6PKG0	LARP1	P24941	CDK2	S291	A294V	294	Missense	distal	3	no	7.485	8.605	EPSD	GDSC	8.148	Gain
CMGC_CDK_CDK2_CDK2_ST	Q6PKG0	LARP1	P24941	CDK2	T303	T303P	303	Missense	central	0	yes	13.148	0.000	EPSD;PhosphoSitePlus	GDSC	8.148	Loss
CMGC_CDK_CDK2_CDK2_ST	Q6PKG0	LARP1	P24941	CDK2	T303	V299L	299	Missense	distal	-4	no	13.148	13.138	EPSD;PhosphoSitePlus	GDSC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	Q6PKG0	LARP1	P24941	CDK2	T376	T376M	376	Missense	central	0	yes	12.729	0.000	EPSD	GDSC	8.148	Loss
CMGC_CDK_CDK2_CDK2_ST	Q6PKG0	LARP1	P24941	CDK2	T376	R375H	375	Missense	proximal	-1	no	12.729	12.278	EPSD	GDSC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	Q6PKG0	LARP1	P24941	CDK2	T376	N382T	382	Missense	distal	6	no	12.729	12.733	EPSD	GDSC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	Q6PKG0	LARP1	P24941	CDK2	S567	R570Q	570	Missense	distal	3	no	11.855	10.112	EPSD	GDSC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	Q6PKG0	LARP1	P24941	CDK2	T724	T724N	724	Missense	central	0	yes	10.308	0.000	EPSD	GDSC	8.148	Loss
CMGC_CDK_CDK2_CDK2_ST	Q6PKG0	LARP1	P24941	CDK2	S774	T780I	780	Missense	distal	6	no	15.408	15.401	EPSD;PhosphoSitePlus	GDSC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	Q6PKG0	LARP1	P24941	CDK2	S774	R778H	778	Missense	distal	4	no	15.408	15.291	EPSD;PhosphoSitePlus	GDSC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	Q6PKG0	LARP1	P24941	CDK2	S774	R781M	781	Missense	distal	7	no	15.408	15.463	EPSD;PhosphoSitePlus	GDSC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	Q6PKG0	LARP1	P24941	CDK2	T782	T780I	780	Missense	proximal	-2	no	13.423	13.302	EPSD	GDSC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	Q6PKG0	LARP1	P24941	CDK2	T782	R778H	778	Missense	distal	-4	no	13.423	13.062	EPSD	GDSC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	Q6PKG0	LARP1	P24941	CDK2	T782	R784H	784	Missense	proximal	2	no	13.423	13.341	EPSD	GDSC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	Q6PKG0	LARP1	P24941	CDK2	T782	R781M	781	Missense	proximal	-1	no	13.423	13.902	EPSD	GDSC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	Q6PKG0	LARP1	P24941	CDK2	T785	T780I	780	Missense	distal	-5	no	13.858	13.898	EPSD	GDSC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	Q6PKG0	LARP1	P24941	CDK2	T785	R778H	778	Missense	distal	-7	no	13.858	13.637	EPSD	GDSC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	Q6PKG0	LARP1	P24941	CDK2	T785	R784H	784	Missense	proximal	-1	no	13.858	13.406	EPSD	GDSC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	Q6PKG0	LARP1	P24941	CDK2	T785	R781M	781	Missense	distal	-4	no	13.858	13.352	EPSD	GDSC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	Q6PKG0	LARP1	P24941	CDK2	T788	R784H	784	Missense	distal	-4	no	13.456	13.095	EPSD	GDSC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	Q6PKG0	LARP1	P24941	CDK2	T788	R781M	781	Missense	distal	-7	no	13.456	13.613	EPSD	GDSC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	Q6PKG0	LARP1	P24941	CDK2	S851	T856M	856	Missense	distal	5	no	15.339	15.673	EPSD	GDSC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	Q6PKG0	LARP1	P24941	CDK2	T856	T856M	856	Missense	central	0	yes	14.229	0.000	EPSD	GDSC	8.148	Loss
CMGC_CDK_CDK2_CDK2_ST	Q6PKG0	LARP1	P24941	CDK2	T1071	P1070A	1070	Missense	proximal	-1	no	14.806	14.536	EPSD	GDSC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	Q6PKG0	LARP1	P24941	CDK2	T1071	Q1068H	1068	Missense	distal	-3	no	14.806	14.894	EPSD	GDSC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	Q8NBZ0	INO80E	P24941	CDK2	T90	P91L	91	Missense	proximal	1	no	13.621	3.800	EPSD	GDSC	8.148	Loss
CMGC_CDK_CDK2_CDK2_ST	Q8NBZ0	INO80E	P24941	CDK2	S98	A104S	104	Missense	distal	6	no	12.680	12.686	EPSD	GDSC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	Q8NBZ0	INO80E	P24941	CDK2	S98	P91L	91	Missense	distal	-7	no	12.680	12.686	EPSD	GDSC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	Q8NBZ0	INO80E	P24941	CDK2	S106	S108P	108	Missense	proximal	2	no	10.328	10.261	EPSD	GDSC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	Q8NBZ0	INO80E	P24941	CDK2	S106	A104S	104	Missense	proximal	-2	no	10.328	9.660	EPSD	GDSC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	Q8NBZ0	INO80E	P24941	CDK2	S127	P126R	126	Missense	proximal	-1	no	12.327	12.897	EPSD	GDSC;CCLE	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	Q8NBZ0	INO80E	P24941	CDK2	S127	L120F	120	Missense	distal	-7	no	12.327	12.693	EPSD	GDSC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	Q8NBZ0	INO80E	P24941	CDK2	S127	Y129*	129	Missense	proximal	2	no	12.327	12.442	EPSD	GDSC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	Q8NBZ0	INO80E	P24941	CDK2	S154	P158H	158	Missense	distal	4	no	14.442	14.204	PhosphoSitePlus	GDSC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	Q9UPN3	MACF1	P24941	CDK2	S280	E283*	283	Missense	distal	3	no	15.487	16.130	EPSD	GDSC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	Q9UPN3	MACF1	P24941	CDK2	S862	D864H	864	Missense	proximal	2	no	15.065	15.146	EPSD	GDSC;CCLE	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	Q9UPN3	MACF1	P24941	CDK2	S898	Q899*	899	Missense	proximal	1	no	8.562	1.403	EPSD	GDSC	8.148	Loss
CMGC_CDK_CDK2_CDK2_ST	Q9UPN3	MACF1	P24941	CDK2	S898	R900W	900	Missense	proximal	2	no	8.562	8.659	EPSD	GDSC;CCLE	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	Q9UPN3	MACF1	P24941	CDK2	S898	D896Y	896	Missense	proximal	-2	no	8.562	8.133	EPSD	GDSC;CCLE	8.148	Loss
CMGC_CDK_CDK2_CDK2_ST	Q9UPN3	MACF1	P24941	CDK2	S907	E912D	912	Missense	distal	5	no	13.460	13.554	EPSD	GDSC;CCLE	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	Q9UPN3	MACF1	P24941	CDK2	S907	R900W	900	Missense	distal	-7	no	13.460	13.630	EPSD	GDSC;CCLE	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	Q9UPN3	MACF1	P24941	CDK2	S907	E912G	912	Missense	distal	5	no	13.460	13.507	EPSD	GDSC;CCLE	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	P33993	MCM7	P24941	CDK2	S121	M118L	118	Missense	distal	-3	no	14.179	13.740	PhosphoSitePlus;EPSD	GDSC;CCLE	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	P33993	MCM7	P24941	CDK2	S365	K370N	370	Missense	distal	5	no	15.149	15.306	EPSD;PhosphoSitePlus	GDSC;CCLE	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	Q9UIF9	BAZ2A	P24941	CDK2	S26	L33P	33	Missense	distal	7	no	14.162	14.132	EPSD	GDSC;CCLE	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	Q9UIF9	BAZ2A	P24941	CDK2	S38	L33P	33	Missense	distal	-5	no	14.496	14.484	EPSD	GDSC;CCLE	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	Q9UIF9	BAZ2A	P24941	CDK2	S135	N141K	141	Missense	distal	6	no	13.535	13.539	EPSD	GDSC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	Q9UIF9	BAZ2A	P24941	CDK2	T548	R553G	553	Missense	distal	5	no	13.987	14.008	EPSD	GDSC;CCLE	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	Q9UIF9	BAZ2A	P24941	CDK2	S613	D620N	620	Missense	distal	7	no	15.705	14.925	EPSD	GDSC;CCLE	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	Q9UIF9	BAZ2A	P24941	CDK2	S613	G619E	619	Missense	distal	6	no	15.705	15.714	EPSD	GDSC;CCLE	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	Q9UIF9	BAZ2A	P24941	CDK2	S1397	M1394K	1394	Missense	distal	-3	no	14.426	14.017	EPSD	GDSC;CCLE	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	Q9UIF9	BAZ2A	P24941	CDK2	S1505	W1504*	1504	Missense	proximal	-1	no	15.590	15.367	EPSD	GDSC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	Q9UIF9	BAZ2A	P24941	CDK2	S1531	R1527Q	1527	Missense	distal	-4	no	8.553	8.578	EPSD	GDSC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	Q9UIF9	BAZ2A	P24941	CDK2	S1770	P1775T	1775	Missense	distal	5	no	10.776	10.751	EPSD	GDSC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	Q6Y7W6	GIGYF2	P24941	CDK2	S26	T25A	25	Missense	proximal	-1	no	13.041	13.034	EPSD	GDSC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	Q6Y7W6	GIGYF2	P24941	CDK2	S30	T25A	25	Missense	distal	-5	no	13.058	13.084	PhosphoSitePlus;EPSD	GDSC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	Q8WUM0	NUP133	P24941	CDK2	S131	I133V	133	Missense	proximal	2	no	13.527	13.672	EPSD	GDSC;CCLE	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	Q8WUM0	NUP133	P24941	CDK2	S1086	S1085N	1085	Missense	proximal	-1	no	8.086	8.483	EPSD	GDSC	8.148	Gain
CMGC_CDK_CDK2_CDK2_ST	P46013	MKI67	P24941	CDK2	T401	R400*	400	Missense	proximal	-1	no	17.455	17.786	EPSD	GDSC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	P46013	MKI67	P24941	CDK2	T525	T525M	525	Missense	central	0	yes	17.005	0.000	EPSD	GDSC	8.148	Loss
CMGC_CDK_CDK2_CDK2_ST	P46013	MKI67	P24941	CDK2	T543	K537R	537	Missense	distal	-6	no	11.508	11.510	EPSD	GDSC;CCLE	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	P46013	MKI67	P24941	CDK2	S713	H710P	710	Missense	distal	-3	no	15.083	14.937	EPSD	GDSC;CCLE	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	P46013	MKI67	P24941	CDK2	S827	R831T	831	Missense	distal	4	no	12.858	13.261	EPSD	GDSC;CCLE	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	P46013	MKI67	P24941	CDK2	S827	R832Q	832	Missense	distal	5	no	12.858	12.711	EPSD	GDSC;CCLE	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	P46013	MKI67	P24941	CDK2	T844	K850E	850	Missense	distal	6	no	12.936	12.925	EPSD	GDSC;CCLE	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	P46013	MKI67	P24941	CDK2	T1017	I1015L	1015	Missense	proximal	-2	no	14.787	14.717	EPSD	GDSC;CCLE	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	P46013	MKI67	P24941	CDK2	T1019	I1015L	1015	Missense	distal	-4	no	9.528	9.620	EPSD	GDSC;CCLE	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	P46013	MKI67	P24941	CDK2	T1083	K1086N	1086	Missense	distal	3	no	10.265	6.994	EPSD	GDSC;CCLE	8.148	Loss
CMGC_CDK_CDK2_CDK2_ST	P46013	MKI67	P24941	CDK2	T1083	P1089S	1089	Missense	distal	6	no	10.265	10.266	EPSD	GDSC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	P46013	MKI67	P24941	CDK2	T1083	K1087R	1087	Missense	distal	4	no	10.265	9.743	EPSD	GDSC;CCLE	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	P46013	MKI67	P24941	CDK2	T1083	M1085K	1085	Missense	proximal	2	no	10.265	9.912	EPSD	GDSC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	P46013	MKI67	P24941	CDK2	T1083	M1085T	1085	Missense	proximal	2	no	10.265	9.876	EPSD	GDSC;CCLE	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	P46013	MKI67	P24941	CDK2	T1091	K1086N	1086	Missense	distal	-5	no	13.129	13.146	EPSD	GDSC;CCLE	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	P46013	MKI67	P24941	CDK2	T1091	P1089S	1089	Missense	proximal	-2	no	13.129	12.478	EPSD	GDSC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	P46013	MKI67	P24941	CDK2	T1091	K1087R	1087	Missense	distal	-4	no	13.129	12.967	EPSD	GDSC;CCLE	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	P46013	MKI67	P24941	CDK2	T1091	M1085K	1085	Missense	distal	-6	no	13.129	13.122	EPSD	GDSC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	P46013	MKI67	P24941	CDK2	T1091	M1085T	1085	Missense	distal	-6	no	13.129	13.122	EPSD	GDSC;CCLE	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	P46013	MKI67	P24941	CDK2	S1131	C1129*	1129	Missense	proximal	-2	no	15.154	14.255	EPSD	GDSC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	P46013	MKI67	P24941	CDK2	T1176	D1183E	1183	Missense	distal	7	no	11.890	11.247	EPSD	GDSC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	P46013	MKI67	P24941	CDK2	T1176	A1180S	1180	Missense	distal	4	no	11.890	11.863	EPSD	GDSC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	P46013	MKI67	P24941	CDK2	T1193	I1187M	1187	Missense	distal	-6	no	11.331	11.336	EPSD	GDSC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	P46013	MKI67	P24941	CDK2	T1213	Q1212*	1212	Missense	proximal	-1	no	13.927	15.136	EPSD	GDSC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	P46013	MKI67	P24941	CDK2	S1253	K1248I	1248	Missense	distal	-5	no	13.686	13.722	EPSD	GDSC;CCLE	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	P46013	MKI67	P24941	CDK2	T1315	V1313M	1313	Missense	proximal	-2	no	13.896	12.461	EPSD	GDSC;CCLE	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	P46013	MKI67	P24941	CDK2	T1327	N1325S	1325	Missense	proximal	-2	no	8.606	9.298	EPSD	GDSC;CCLE	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	P46013	MKI67	P24941	CDK2	T1327	G1328V	1328	Missense	proximal	1	no	8.606	-0.993	EPSD	GDSC;CCLE	8.148	Loss
CMGC_CDK_CDK2_CDK2_ST	P46013	MKI67	P24941	CDK2	T1327	R1332W	1332	Missense	distal	5	no	8.606	8.773	EPSD	GDSC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	P46013	MKI67	P24941	CDK2	T1335	G1328V	1328	Missense	distal	-7	no	13.492	13.187	EPSD	GDSC;CCLE	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	P46013	MKI67	P24941	CDK2	T1335	R1332W	1332	Missense	distal	-3	no	13.492	13.573	EPSD	GDSC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	P46013	MKI67	P24941	CDK2	T1485	T1484A	1484	Missense	proximal	-1	no	8.583	8.576	EPSD	GDSC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	P46013	MKI67	P24941	CDK2	T1503	Q1497L	1497	Missense	distal	-6	no	14.340	14.338	EPSD	GDSC;CCLE	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	P46013	MKI67	P24941	CDK2	T1531	A1534T	1534	Missense	distal	3	no	12.626	13.023	EPSD	GDSC;CCLE	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	P46013	MKI67	P24941	CDK2	T1531	L1527F	1527	Missense	distal	-4	no	12.626	12.076	EPSD	GDSC;CCLE	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	P46013	MKI67	P24941	CDK2	T1540	A1534T	1534	Missense	distal	-6	no	10.897	10.899	EPSD	GDSC;CCLE	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	P46013	MKI67	P24941	CDK2	T1540	H1539Q	1539	Missense	proximal	-1	no	10.897	10.471	EPSD	GDSC;CCLE	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	P46013	MKI67	P24941	CDK2	S1546	H1539Q	1539	Missense	distal	-7	no	11.331	11.165	EPSD	GDSC;CCLE	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	P46013	MKI67	P24941	CDK2	T1577	A1582V	1582	Missense	distal	5	no	13.129	13.086	EPSD	GDSC;CCLE	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	P46013	MKI67	P24941	CDK2	T1577	Q1583R	1583	Missense	distal	6	no	13.129	13.107	EPSD	GDSC;CCLE	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	P46013	MKI67	P24941	CDK2	S1618	Q1619P	1619	Missense	proximal	1	no	3.805	11.717	EPSD	GDSC;CCLE	8.148	Gain
CMGC_CDK_CDK2_CDK2_ST	P46013	MKI67	P24941	CDK2	S1679	Q1682H	1682	Missense	distal	3	no	10.457	11.504	EPSD	GDSC;CCLE	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	P46013	MKI67	P24941	CDK2	T1699	S1704C	1704	Missense	distal	5	no	13.662	13.996	EPSD	GDSC;CCLE	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	P46013	MKI67	P24941	CDK2	T1747	L1744P	1744	Missense	distal	-3	no	15.182	15.253	EPSD	GDSC;CCLE	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	P46013	MKI67	P24941	CDK2	T1747	S1750N	1750	Missense	distal	3	no	15.182	14.585	EPSD	GDSC;CCLE	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	P46013	MKI67	P24941	CDK2	S1861	K1855*	1855	Missense	distal	-6	no	12.594	12.602	EPSD	GDSC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	P46013	MKI67	P24941	CDK2	T1869	T1869A	1869	Missense	central	0	yes	14.825	0.000	EPSD	GDSC;CCLE	8.148	Loss
CMGC_CDK_CDK2_CDK2_ST	P46013	MKI67	P24941	CDK2	T1972	T1977I	1977	Missense	distal	5	no	9.746	9.864	EPSD	GDSC;CCLE	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	P46013	MKI67	P24941	CDK2	S1983	T1977I	1977	Missense	distal	-6	no	13.963	13.965	EPSD	GDSC;CCLE	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	P46013	MKI67	P24941	CDK2	S1983	C1981F	1981	Missense	proximal	-2	no	13.963	13.911	EPSD	GDSC;CCLE	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	P46013	MKI67	P24941	CDK2	T1991	Q1997*	1997	Missense	distal	6	no	14.501	14.478	EPSD	GDSC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	P46013	MKI67	P24941	CDK2	T2085	Q2084R	2084	Missense	proximal	-1	no	14.490	15.368	EPSD	GDSC;CCLE	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	P46013	MKI67	P24941	CDK2	T2094	T2093I	2093	Missense	proximal	-1	no	7.906	8.152	EPSD	GDSC;CCLE	8.148	Gain
CMGC_CDK_CDK2_CDK2_ST	P46013	MKI67	P24941	CDK2	S2105	E2109*	2109	Missense	distal	4	no	14.933	14.541	EPSD	GDSC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	P46013	MKI67	P24941	CDK2	T2113	E2109*	2109	Missense	distal	-4	no	12.560	11.597	EPSD	GDSC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	P46013	MKI67	P24941	CDK2	T2113	T2117I	2117	Missense	distal	4	no	12.560	12.249	EPSD	GDSC;CCLE	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	P46013	MKI67	P24941	CDK2	T2123	T2117I	2117	Missense	distal	-6	no	15.069	15.072	EPSD	GDSC;CCLE	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	P46013	MKI67	P24941	CDK2	T2203	I2205V	2205	Missense	proximal	2	no	8.173	8.318	EPSD	GDSC;CCLE	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	P46013	MKI67	P24941	CDK2	T2203	P2204S	2204	Missense	proximal	1	no	8.173	-3.093	EPSD	GDSC	8.148	Loss
CMGC_CDK_CDK2_CDK2_ST	P46013	MKI67	P24941	CDK2	T2212	I2205V	2205	Missense	distal	-7	no	10.202	10.028	EPSD	GDSC;CCLE	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	P46013	MKI67	P24941	CDK2	S2223	S2223Y	2223	Missense	central	0	yes	12.346	0.000	EPSD	GDSC;CCLE	8.148	Loss
CMGC_CDK_CDK2_CDK2_ST	P46013	MKI67	P24941	CDK2	T2325	G2318D	2318	Missense	distal	-7	no	12.538	12.455	EPSD	GDSC;CCLE	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	P46013	MKI67	P24941	CDK2	T2380	R2379*	2379	Missense	proximal	-1	no	12.939	13.271	EPSD	GDSC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	P46013	MKI67	P24941	CDK2	T2446	G2448D	2448	Missense	proximal	2	no	12.171	12.050	EPSD	GDSC;CCLE	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	P46013	MKI67	P24941	CDK2	T2446	S2453L	2453	Missense	distal	7	no	12.171	12.353	EPSD	GDSC;CCLE	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	P46013	MKI67	P24941	CDK2	T2446	K2441E	2441	Missense	distal	-5	no	12.171	12.205	EPSD	GDSC;CCLE	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	P46013	MKI67	P24941	CDK2	T2455	G2448D	2448	Missense	distal	-7	no	9.096	9.013	EPSD	GDSC;CCLE	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	P46013	MKI67	P24941	CDK2	T2455	S2453L	2453	Missense	proximal	-2	no	9.096	9.523	EPSD	GDSC;CCLE	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	P46013	MKI67	P24941	CDK2	T2540	R2547S	2547	Missense	distal	7	no	8.151	7.510	EPSD	GDSC;CCLE	8.148	Loss
CMGC_CDK_CDK2_CDK2_ST	P46013	MKI67	P24941	CDK2	S2588	T2594S	2594	Missense	distal	6	no	14.167	14.160	EPSD	GDSC;CCLE	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	P46013	MKI67	P24941	CDK2	T2781	S2783G	2783	Missense	proximal	2	no	9.210	9.261	EPSD	GDSC;CCLE	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	P46013	MKI67	P24941	CDK2	T2781	R2786W	2786	Missense	distal	5	no	9.210	9.376	EPSD	GDSC;CCLE	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	P46013	MKI67	P24941	CDK2	T2927	T2927A	2927	Missense	central	0	yes	14.719	0.000	EPSD	GDSC;CCLE	8.148	Loss
CMGC_CDK_CDK2_CDK2_ST	Q9NS91	RAD18	P24941	CDK2	S103	K110E	110	Missense	distal	7	no	12.281	12.612	EPSD	GDSC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	Q9NS91	RAD18	P24941	CDK2	T118	T118A	118	Missense	central	0	yes	13.363	0.000	EPSD	GDSC;CCLE	8.148	Loss
CMGC_CDK_CDK2_CDK2_ST	Q9NS91	RAD18	P24941	CDK2	S158	E152*	152	Missense	distal	-6	no	16.223	16.229	EPSD	GDSC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	Q9NS91	RAD18	P24941	CDK2	S403	S409F	409	Missense	distal	6	no	10.956	10.937	EPSD	GDSC;CCLE	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	Q9NS91	RAD18	P24941	CDK2	S409	S409F	409	Missense	central	0	yes	17.115	0.000	EPSD	GDSC;CCLE	8.148	Loss
CMGC_CDK_CDK2_CDK2_ST	Q9NS91	RAD18	P24941	CDK2	S471	R473I	473	Missense	proximal	2	no	15.137	14.955	EPSD	GDSC;CCLE	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	P26358	DNMT1	P24941	CDK2	S115	R114K	114	Missense	proximal	-1	no	8.525	7.855	EPSD	GDSC;CCLE	8.148	Loss
CMGC_CDK_CDK2_CDK2_ST	P26358	DNMT1	P24941	CDK2	S127	N126H	126	Missense	proximal	-1	no	14.636	14.829	EPSD	GDSC;CCLE	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	Q2NL82	TSR1	P24941	CDK2	T39	K46E	46	Missense	distal	7	no	8.127	8.458	EPSD	GDSC;CCLE	8.148	Gain
CMGC_CDK_CDK2_CDK2_ST	Q2NL82	TSR1	P24941	CDK2	T490	R492G	492	Missense	proximal	2	no	15.273	15.232	PhosphoSitePlus	GDSC;CCLE	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	O75616	ERAL1	P24941	CDK2	S53	A51T	51	Missense	proximal	-2	no	8.647	8.598	EPSD	GDSC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	O75616	ERAL1	P24941	CDK2	T168	Q162*	162	Missense	distal	-6	no	13.521	13.527	EPSD	GDSC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	P38398	BRCA1	P24941	CDK2	S896	Q895*	895	Missense	proximal	-1	no	16.991	18.200	EPSD	GDSC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	Q9H1E3	NUCKS1	P24941	CDK2	T179	P180R	180	Missense	proximal	1	no	10.411	0.613	EPSD	GDSC;CCLE	8.148	Loss
CMGC_CDK_CDK2_CDK2_ST	Q9H1E3	NUCKS1	P24941	CDK2	S181	P180R	180	Missense	proximal	-1	no	16.204	16.774	PhosphoSitePlus	GDSC;CCLE	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	Q9H3D4	TP63	P24941	CDK2	S160	T155I	155	Missense	distal	-5	no	12.081	12.122	EPSD	GDSC;CCLE	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	Q9H3D4	TP63	P24941	CDK2	S162	T155I	155	Missense	distal	-7	no	10.982	11.179	EPSD	GDSC;CCLE	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	Q9H3D4	TP63	P24941	CDK2	S455	S457P	457	Missense	proximal	2	no	13.585	13.519	EPSD	GDSC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	Q9H3D4	TP63	P24941	CDK2	S463	S457P	457	Missense	distal	-6	no	11.144	11.145	EPSD	GDSC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	Q9H3D4	TP63	P24941	CDK2	T491	Q485R	485	Missense	distal	-6	no	13.063	13.062	PhosphoSitePlus	GDSC;CCLE	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	O75152	ZC3H11A	P24941	CDK2	S108	P106A	106	Missense	proximal	-2	no	14.733	14.750	EPSD	GDSC;CCLE	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	O75152	ZC3H11A	P24941	CDK2	T179	L182V	182	Missense	distal	3	no	11.614	12.606	EPSD	GDSC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	O75152	ZC3H11A	P24941	CDK2	T185	L182V	182	Missense	distal	-3	no	13.808	14.022	EPSD	GDSC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	O75152	ZC3H11A	P24941	CDK2	T502	L509P	509	Missense	distal	7	no	11.820	11.790	EPSD	GDSC;CCLE	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	O75152	ZC3H11A	P24941	CDK2	T502	R507W	507	Missense	distal	5	no	11.820	11.987	EPSD	GDSC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	O75152	ZC3H11A	P24941	CDK2	T515	T515R	515	Missense	central	0	yes	8.760	0.000	EPSD	GDSC;CCLE	8.148	Loss
CMGC_CDK_CDK2_CDK2_ST	O75152	ZC3H11A	P24941	CDK2	S781	I777V	777	Missense	distal	-4	no	10.570	10.673	EPSD	GDSC;CCLE	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	Q8IXJ6	SIRT2	P24941	CDK2	S25	D24Y	24	Missense	proximal	-1	no	9.646	9.329	EPSD	GDSC;CCLE	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	P55795	HNRNPH2	P24941	CDK2	S63	E65D	65	Missense	proximal	2	no	8.590	8.491	EPSD	GDSC;CCLE	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	Q9P270	SLAIN2	P24941	CDK2	S343	P346S	346	Missense	distal	3	no	14.013	14.047	EPSD	GDSC;CCLE	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	Q9P270	SLAIN2	P24941	CDK2	S345	P346S	346	Missense	proximal	1	no	11.858	0.592	EPSD	GDSC;CCLE	8.148	Loss
CMGC_CDK_CDK2_CDK2_ST	Q9P270	SLAIN2	P24941	CDK2	S349	P346S	346	Missense	distal	-3	no	14.807	14.902	EPSD	GDSC;CCLE	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	Q9P270	SLAIN2	P24941	CDK2	S353	P346S	346	Missense	distal	-7	no	11.669	11.489	EPSD	GDSC;CCLE	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	Q9P270	SLAIN2	P24941	CDK2	S366	R369Q	369	Missense	distal	3	no	17.857	16.114	EPSD	GDSC;CCLE	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	Q9P270	SLAIN2	P24941	CDK2	S377	P378S	378	Missense	proximal	1	no	15.717	4.452	EPSD	GDSC;CCLE	8.148	Loss
CMGC_CDK_CDK2_CDK2_ST	Q13309	SKP2	P24941	CDK2	S179	L174F	174	Missense	distal	-5	no	17.503	17.564	EPSD	GDSC;CCLE	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	Q13309	SKP2	P24941	CDK2	S179	A175S	175	Missense	distal	-4	no	17.503	17.917	EPSD	GDSC;CCLE	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	P04637	TP53	P24941	CDK2	S33	Q38*	38	Missense	distal	5	no	15.549	15.785	EPSD	GDSC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	P04637	TP53	P24941	CDK2	S37	Q38*	38	Missense	proximal	1	no	9.176	2.017	EPSD	GDSC	8.148	Loss
CMGC_CDK_CDK2_CDK2_ST	P04637	TP53	P24941	CDK2	T81	A74S	74	Missense	distal	-7	no	14.045	13.701	EPSD	GDSC;CCLE	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	P04637	TP53	P24941	CDK2	S127	Y126*	126	Missense	proximal	-1	no	15.119	15.582	EPSD	GDSC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	P04637	TP53	P24941	CDK2	S127	K120*	120	Missense	distal	-7	no	15.119	15.642	EPSD	GDSC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	P04637	TP53	P24941	CDK2	T150	Q144*	144	Missense	distal	-6	no	10.420	10.426	EPSD	GDSC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	P04637	TP53	P24941	CDK2	T150	W146*	146	Missense	distal	-4	no	10.420	10.688	EPSD	GDSC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	P04637	TP53	P24941	CDK2	S315	Q317*	317	Missense	proximal	2	no	14.293	14.406	PhosphoSitePlus	GDSC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	P04637	TP53	P24941	CDK2	S315	K319*	319	Missense	distal	4	no	14.293	13.516	PhosphoSitePlus	GDSC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	P04637	TP53	P24941	CDK2	S367	G360V	360	Missense	distal	-7	no	8.674	8.370	EPSD	GDSC;CCLE	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	Q9C0D5	TANC1	P24941	CDK2	S67	S63C	63	Missense	distal	-4	no	13.809	12.703	EPSD	GDSC;CCLE	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	Q9C0D5	TANC1	P24941	CDK2	S85	V89A	89	Missense	distal	4	no	13.901	13.714	EPSD	GDSC;CCLE	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	Q9C0D5	TANC1	P24941	CDK2	S132	N127D	127	Missense	distal	-5	no	12.632	12.670	EPSD	GDSC;CCLE	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	Q9C0D5	TANC1	P24941	CDK2	S132	P133Q	133	Missense	proximal	1	no	12.632	4.720	EPSD	GDSC;CCLE	8.148	Loss
CMGC_CDK_CDK2_CDK2_ST	Q9C0D5	TANC1	P24941	CDK2	S132	P129S	129	Missense	distal	-3	no	12.632	12.727	EPSD	GDSC;CCLE	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	Q9C0D5	TANC1	P24941	CDK2	S214	L219M	219	Missense	distal	5	no	12.466	12.733	EPSD	GDSC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	Q9C0D5	TANC1	P24941	CDK2	S444	M437T	437	Missense	distal	-7	no	14.217	13.714	EPSD	GDSC;CCLE	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	Q9C0D5	TANC1	P24941	CDK2	S444	M437V	437	Missense	distal	-7	no	14.217	13.736	EPSD	GDSC;CCLE	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	Q9C0D5	TANC1	P24941	CDK2	T478	A476T	476	Missense	proximal	-2	no	14.736	14.686	EPSD	GDSC;CCLE	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	Q9C0D5	TANC1	P24941	CDK2	T478	A485T	485	Missense	distal	7	no	14.736	14.047	EPSD	GDSC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	Q9C0D5	TANC1	P24941	CDK2	T1147	M1150V	1150	Missense	distal	3	no	12.183	13.031	EPSD	GDSC;CCLE	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	Q9C0D5	TANC1	P24941	CDK2	T1147	G1145D	1145	Missense	proximal	-2	no	12.183	12.791	EPSD	GDSC;CCLE	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	Q9C0D5	TANC1	P24941	CDK2	S1564	R1569T	1569	Missense	distal	5	no	14.039	13.907	PhosphoSitePlus	GDSC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	Q9C0D5	TANC1	P24941	CDK2	T1573	R1569T	1569	Missense	distal	-4	no	15.927	16.336	EPSD	GDSC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	Q9C0D5	TANC1	P24941	CDK2	S1668	T1661N	1661	Missense	distal	-7	no	13.364	13.285	EPSD	GDSC;CCLE	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	Q5JTV8	TOR1AIP1	P24941	CDK2	T47	T47A	47	Missense	central	0	yes	12.574	0.000	EPSD	GDSC;CCLE	8.148	Loss
CMGC_CDK_CDK2_CDK2_ST	Q5JTV8	TOR1AIP1	P24941	CDK2	T286	A291T	291	Missense	distal	5	no	11.226	11.191	EPSD	GDSC	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	Q5JTV8	TOR1AIP1	P24941	CDK2	T286	Q288*	288	Missense	proximal	2	no	11.226	11.340	EPSD	GDSC	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	Q8TAP6	CEP76	P24941	CDK2	S83	V76I	76	Missense	distal	-7	no	15.263	15.438	PhosphoSitePlus	GDSC;CCLE	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	Q8TAP6	CEP76	P24941	CDK2	S83	K85T	85	Missense	proximal	2	no	15.263	15.226	PhosphoSitePlus	GDSC;CCLE	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	Q8TAP6	CEP76	P24941	CDK2	T335	A329T	329	Missense	distal	-6	no	17.340	17.341	EPSD	GDSC	8.148	Up-regulation
Atypical_Alpha_eEF2K_EEF2K_ST	P13639	EEF2	O00418	EEF2K	T54	A47V	47	Missense	distal	-7	no	88.276	74.777	EPSD	GDSC;CCLE	53.998	Down-regulation
Atypical_Alpha_eEF2K_EEF2K_ST	O00418	EEF2K	O00418	EEF2K	S71	Y69H	69	Missense	proximal	-2	no	59.038	60.219	EPSD	GDSC;CCLE	53.998	Up-regulation
Atypical_Alpha_eEF2K_EEF2K_ST	O00418	EEF2K	O00418	EEF2K	S441	S438N	438	Missense	distal	-3	no	90.329	93.325	EPSD;PhosphoSitePlus	GDSC;CCLE	53.998	Up-regulation
Atypical_Alpha_eEF2K_EEF2K_ST	O00418	EEF2K	O00418	EEF2K	S441	E434*	434	Missense	distal	-7	no	90.329	81.240	EPSD;PhosphoSitePlus	GDSC	53.998	Down-regulation
Atypical_Alpha_eEF2K_EEF2K_ST	O00418	EEF2K	O00418	EEF2K	S445	G449S	449	Missense	distal	4	no	106.516	104.740	EPSD;PhosphoSitePlus	GDSC	53.998	Down-regulation
Atypical_Alpha_eEF2K_EEF2K_ST	O00418	EEF2K	O00418	EEF2K	S445	S438N	438	Missense	distal	-7	no	106.516	96.888	EPSD;PhosphoSitePlus	GDSC;CCLE	53.998	Down-regulation
Atypical_Alpha_eEF2K_EEF2K_ST	O00418	EEF2K	O00418	EEF2K	S474	V481I	481	Missense	distal	7	no	112.113	111.474	EPSD;PhosphoSitePlus	GDSC	53.998	Down-regulation
Atypical_Alpha_eEF2K_EEF2K_ST	O00418	EEF2K	O00418	EEF2K	S492	N490T	490	Missense	proximal	-2	no	54.735	58.484	EPSD	GDSC	53.998	Up-regulation
Atypical_Alpha_eEF2K_EEF2K_ST	O00418	EEF2K	O00418	EEF2K	S492	H495P	495	Missense	distal	3	no	54.735	61.045	EPSD	GDSC	53.998	Up-regulation
Atypical_Alpha_eEF2K_EEF2K_ST	O00418	EEF2K	O00418	EEF2K	S492	S491P	491	Missense	proximal	-1	no	54.735	54.651	EPSD	GDSC	53.998	Down-regulation
Atypical_Alpha_eEF2K_EEF2K_ST	O00418	EEF2K	O00418	EEF2K	S500	H495P	495	Missense	distal	-5	no	98.317	100.321	EPSD;PhosphoSitePlus	GDSC	53.998	Up-regulation
Atypical_Alpha_eEF2K_EEF2K_ST	O00418	EEF2K	O00418	EEF2K	S627	G623S	623	Missense	distal	-4	no	52.783	54.375	EPSD	GDSC	53.998	Gain
AGC_PKG_PRKG1_ST	P50552	VASP	Q13976	PRKG1	S157	R155Q	155	Missense	proximal	-2	no	13.230	10.265	EPSD;PhosphoSitePlus	GDSC	7.092	Down-regulation
AGC_PKG_PRKG1_ST	P50552	VASP	Q13976	PRKG1	S157	N158H	158	Missense	proximal	1	no	13.230	13.273	EPSD;PhosphoSitePlus	GDSC	7.092	Up-regulation
AGC_PKG_PRKG1_ST	P61224	RAP1B	Q13976	PRKG1	S179	Q182P	182	Missense	distal	3	no	11.839	12.083	PhosphoSitePlus	GDSC;CCLE	7.092	Up-regulation
AGC_PKG_PRKG1_ST	P61224	RAP1B	Q13976	PRKG1	S180	Q182P	182	Missense	proximal	2	no	10.845	10.765	EPSD	GDSC;CCLE	7.092	Down-regulation
AGC_PKG_PRKG1_ST	P61586	RHOA	Q13976	PRKG1	S73	Y66D	66	Missense	distal	-7	no	7.618	7.345	EPSD	GDSC;CCLE	7.092	Down-regulation
AGC_PKG_PRKG1_ST	P21731	TBXA2R	Q13976	PRKG1	S324	S324N	324	Missense	central	0	yes	11.181	0.000	EPSD	GDSC	7.092	Loss
AGC_PKG_PRKG1_ST	P21731	TBXA2R	Q13976	PRKG1	S329	S324N	324	Missense	distal	-5	no	11.239	11.331	EPSD	GDSC	7.092	Up-regulation
AGC_PKG_PRKG1_ST	P21731	TBXA2R	Q13976	PRKG1	S331	S324N	324	Missense	distal	-7	no	9.685	9.077	EPSD;PhosphoSitePlus	GDSC	7.092	Down-regulation
AGC_PKG_PRKG1_ST	P35520	CBS	Q13976	PRKG1	S525	F531L	531	Missense	distal	6	no	8.571	8.743	EPSD;PhosphoSitePlus	GDSC	7.092	Up-regulation
AGC_PKG_PRKG1_ST	P35520	CBS	Q13976	PRKG1	S525	G532R	532	Missense	distal	7	no	8.571	8.684	EPSD;PhosphoSitePlus	GDSC	7.092	Up-regulation
AGC_PKG_PRKG1_ST	Q9Y210	TRPC6	Q13976	PRKG1	T70	E74K	74	Missense	distal	4	no	12.250	12.135	PhosphoSitePlus;EPSD	GDSC	7.092	Down-regulation
AGC_PKG_PRKG1_ST	Q9Y210	TRPC6	Q13976	PRKG1	S94	R101C	101	Missense	distal	7	no	9.035	8.923	EPSD	GDSC;CCLE	7.092	Down-regulation
AGC_PKG_PRKG1_ST	Q9Y210	TRPC6	Q13976	PRKG1	S836	S836N	836	Missense	central	0	yes	8.089	0.000	EPSD	GDSC;CCLE	7.092	Loss
AGC_PKG_PRKG1_ST	P35367	HRH1	Q13976	PRKG1	S363	S363P	363	Missense	central	0	yes	10.249	0.000	EPSD	GDSC	7.092	Loss
AGC_PKG_PRKG1_ST	Q9NS28	RGS18	Q13976	PRKG1	S64	S63P	63	Missense	proximal	-1	no	8.410	8.306	EPSD	GDSC;CCLE	7.092	Down-regulation
AGC_PKG_PRKG1_ST	Q9Y613	FHOD1	Q13976	PRKG1	S357	R351W	351	Missense	distal	-6	no	15.265	14.437	EPSD	GDSC;CCLE	7.092	Down-regulation
AGC_PKG_PRKG1_ST	Q9Y613	FHOD1	Q13976	PRKG1	S357	S357P	357	Missense	central	0	yes	15.265	0.000	EPSD	GDSC;CCLE	7.092	Loss
AGC_PKG_PRKG1_ST	Q9Y613	FHOD1	Q13976	PRKG1	S357	K355E	355	Missense	proximal	-2	no	15.265	11.742	EPSD	GDSC;CCLE	7.092	Down-regulation
AGC_PKG_PRKG1_ST	Q9Y613	FHOD1	Q13976	PRKG1	S358	R351W	351	Missense	distal	-7	no	7.757	5.992	EPSD	GDSC;CCLE	7.092	Loss
AGC_PKG_PRKG1_ST	Q9Y613	FHOD1	Q13976	PRKG1	S358	S357P	357	Missense	proximal	-1	no	7.757	7.654	EPSD	GDSC;CCLE	7.092	Down-regulation
AGC_PKG_PRKG1_ST	Q9Y613	FHOD1	Q13976	PRKG1	S358	K355E	355	Missense	distal	-3	no	7.757	3.174	EPSD	GDSC;CCLE	7.092	Loss
AGC_PKG_PRKG1_ST	Q9Y613	FHOD1	Q13976	PRKG1	S364	S357P	357	Missense	distal	-7	no	8.240	7.472	EPSD	GDSC;CCLE	7.092	Down-regulation
AGC_PKG_PRKG1_ST	Q9Y613	FHOD1	Q13976	PRKG1	T465	G468R	468	Missense	distal	3	no	7.320	7.093	EPSD	GDSC	7.092	Down-regulation
AGC_PKG_PRKG1_ST	Q9Y613	FHOD1	Q13976	PRKG1	S540	I541T	541	Missense	proximal	1	no	8.772	9.186	EPSD	GDSC;CCLE	7.092	Up-regulation
AGC_PKG_PRKG1_ST	P78347	GTF2I	Q13976	PRKG1	S95	R101W	101	Missense	distal	6	no	7.447	7.788	EPSD	GDSC;CCLE	7.092	Up-regulation
AGC_PKG_PRKG1_ST	P78347	GTF2I	Q13976	PRKG1	S103	R101W	101	Missense	proximal	-2	no	7.368	2.037	EPSD	GDSC;CCLE	7.092	Loss
AGC_PKG_PRKG1_ST	Q14847	LASP1	Q13976	PRKG1	S61	A66V	66	Missense	distal	5	no	7.442	7.392	EPSD	GDSC	7.092	Down-regulation
AGC_PKG_PRKG1_ST	Q684P5	RAP1GAP2	Q13976	PRKG1	S518	H519Y	519	Missense	proximal	1	no	9.982	9.840	EPSD	GDSC;CCLE	7.092	Down-regulation
AGC_PKG_PRKG1_ST	Q684P5	RAP1GAP2	Q13976	PRKG1	S520	H519Y	519	Missense	proximal	-1	no	8.974	8.929	EPSD	GDSC;CCLE	7.092	Down-regulation
AGC_PKG_PRKG1_ST	Q684P5	RAP1GAP2	Q13976	PRKG1	S556	R557Q	557	Missense	proximal	1	no	7.102	6.938	EPSD	GDSC;CCLE	7.092	Loss
AGC_PKG_PRKG1_ST	Q684P5	RAP1GAP2	Q13976	PRKG1	S564	R557Q	557	Missense	distal	-7	no	13.411	12.734	EPSD	GDSC;CCLE	7.092	Down-regulation
AGC_PKG_PRKG1_ST	Q684P5	RAP1GAP2	Q13976	PRKG1	S599	G597R	597	Missense	proximal	-2	no	6.622	10.110	EPSD	GDSC;CCLE	7.092	Gain
AGC_PKG_PRKG1_ST	Q684P5	RAP1GAP2	Q13976	PRKG1	S600	G597R	597	Missense	distal	-3	no	5.121	9.712	EPSD	GDSC;CCLE	7.092	Gain
AGC_PKG_PRKG1_ST	Q8WZ42	TTN	Q13976	PRKG1	S79	K81R	81	Missense	proximal	2	no	10.417	10.432	EPSD	GDSC	7.092	Up-regulation
AGC_PKG_PRKG1_ST	Q8WZ42	TTN	Q13976	PRKG1	S112	R116T	116	Missense	distal	4	no	9.072	9.131	EPSD	GDSC;CCLE	7.092	Up-regulation
AGC_PKG_PRKG1_ST	Q8WZ42	TTN	Q13976	PRKG1	S112	V107I	107	Missense	distal	-5	no	9.072	9.175	EPSD	GDSC;CCLE	7.092	Up-regulation
AGC_PKG_PRKG1_ST	Q8WZ42	TTN	Q13976	PRKG1	T300	R297Q	297	Missense	distal	-3	no	8.818	4.983	EPSD	GDSC;CCLE	7.092	Loss
AGC_PKG_PRKG1_ST	Q8WZ42	TTN	Q13976	PRKG1	S308	P309S	309	Missense	proximal	1	no	9.833	10.094	EPSD	GDSC	7.092	Up-regulation
AGC_PKG_PRKG1_ST	Q8WZ42	TTN	Q13976	PRKG1	S314	P309S	309	Missense	distal	-5	no	8.828	8.713	EPSD	GDSC	7.092	Down-regulation
AGC_PKG_PRKG1_ST	Q8WZ42	TTN	Q13976	PRKG1	S742	A743V	743	Missense	proximal	1	no	7.300	6.977	EPSD	GDSC;CCLE	7.092	Loss
AGC_PKG_PRKG1_ST	Q8WZ42	TTN	Q13976	PRKG1	S755	R752H	752	Missense	distal	-3	no	8.887	2.820	EPSD	GDSC;CCLE	7.092	Loss
AGC_PKG_PRKG1_ST	Q8WZ42	TTN	Q13976	PRKG1	S1348	S1348R	1348	Missense	central	0	yes	7.863	0.000	EPSD	GDSC;CCLE	7.092	Loss
AGC_PKG_PRKG1_ST	Q8WZ42	TTN	Q13976	PRKG1	S1348	L1342I	1342	Missense	distal	-6	no	7.863	7.854	EPSD	GDSC;CCLE	7.092	Down-regulation
AGC_PKG_PRKG1_ST	Q8WZ42	TTN	Q13976	PRKG1	S1428	A1435E	1435	Missense	distal	7	no	11.058	10.992	EPSD	GDSC;CCLE	7.092	Down-regulation
AGC_PKG_PRKG1_ST	Q8WZ42	TTN	Q13976	PRKG1	S1433	A1435E	1435	Missense	proximal	2	no	9.496	9.443	EPSD	GDSC;CCLE	7.092	Down-regulation
AGC_PKG_PRKG1_ST	Q8WZ42	TTN	Q13976	PRKG1	S1438	A1435E	1435	Missense	distal	-3	no	9.145	6.783	EPSD	GDSC;CCLE	7.092	Loss
AGC_PKG_PRKG1_ST	Q8WZ42	TTN	Q13976	PRKG1	S1539	S1539P	1539	Missense	central	0	yes	8.148	0.000	EPSD	GDSC;CCLE	7.092	Loss
AGC_PKG_PRKG1_ST	Q8WZ42	TTN	Q13976	PRKG1	S1540	S1539P	1539	Missense	proximal	-1	no	8.248	8.144	EPSD	GDSC;CCLE	7.092	Down-regulation
AGC_PKG_PRKG1_ST	Q8WZ42	TTN	Q13976	PRKG1	S1571	E1569A	1569	Missense	proximal	-2	no	6.795	8.339	EPSD	GDSC;CCLE	7.092	Gain
AGC_PKG_PRKG1_ST	Q8WZ42	TTN	Q13976	PRKG1	T1710	R1716C	1716	Missense	distal	6	no	8.254	8.505	EPSD	GDSC;CCLE	7.092	Up-regulation
AGC_PKG_PRKG1_ST	Q8WZ42	TTN	Q13976	PRKG1	S3213	S3213C	3213	Missense	central	0	yes	7.889	0.000	EPSD	GDSC;CCLE	7.092	Loss
AGC_PKG_PRKG1_ST	Q8WZ42	TTN	Q13976	PRKG1	S3228	A3222V	3222	Missense	distal	-6	no	7.664	7.327	EPSD	GDSC;CCLE	7.092	Down-regulation
AGC_PKG_PRKG1_ST	Q8WZ42	TTN	Q13976	PRKG1	S3369	R3363H	3363	Missense	distal	-6	no	9.084	8.559	EPSD	GDSC	7.092	Down-regulation
AGC_PKG_PRKG1_ST	Q8WZ42	TTN	Q13976	PRKG1	S10146	P10149T	10149	Missense	distal	3	no	7.825	7.568	EPSD	GDSC	7.092	Down-regulation
AGC_PKG_PRKG1_ST	Q8WZ42	TTN	Q13976	PRKG1	S10146	E10152K	10152	Missense	distal	6	no	7.825	7.608	EPSD	GDSC	7.092	Down-regulation
AGC_PKG_PRKG1_ST	Q8WZ42	TTN	Q13976	PRKG1	T17118	T17122A	17122	Missense	distal	4	no	8.734	8.731	EPSD	GDSC	7.092	Down-regulation
AGC_PKG_PRKG1_ST	Q8WZ42	TTN	Q13976	PRKG1	T21837	E21835K	21835	Missense	proximal	-2	no	5.649	9.171	EPSD	GDSC	7.092	Gain
AGC_PKG_PRKG1_ST	Q8WZ42	TTN	Q13976	PRKG1	S21840	E21835K	21835	Missense	distal	-5	no	10.089	9.908	EPSD	GDSC	7.092	Down-regulation
AGC_PKG_PRKG1_ST	Q8WZ42	TTN	Q13976	PRKG1	S21842	E21835K	21835	Missense	distal	-7	no	8.314	9.315	EPSD	GDSC	7.092	Up-regulation
AGC_PKG_PRKG1_ST	Q8WZ42	TTN	Q13976	PRKG1	T22152	L22150F	22150	Missense	proximal	-2	no	7.016	8.140	EPSD	GDSC	7.092	Gain
AGC_PKG_PRKG1_ST	Q8WZ42	TTN	Q13976	PRKG1	S33088	R33082Q	33082	Missense	distal	-6	no	7.973	7.676	EPSD	GDSC	7.092	Down-regulation
AGC_PKG_PRKG1_ST	Q8WZ42	TTN	Q13976	PRKG1	T33089	R33082Q	33082	Missense	distal	-7	no	8.762	8.085	EPSD	GDSC	7.092	Down-regulation
AGC_PKG_PRKG1_ST	Q8WZ42	TTN	Q13976	PRKG1	S33245	S33247L	33247	Missense	proximal	2	no	8.318	8.175	EPSD	GDSC	7.092	Down-regulation
AGC_PKG_PRKG1_ST	Q8WZ42	TTN	Q13976	PRKG1	S33247	S33247L	33247	Missense	central	0	yes	11.582	0.000	EPSD	GDSC	7.092	Loss
AGC_PKG_PRKG1_ST	Q05469	LIPE	Q13976	PRKG1	S200	G205R	205	Missense	distal	5	no	7.726	7.802	EPSD	GDSC;CCLE	7.092	Up-regulation
AGC_PKG_PRKG1_ST	Q05469	LIPE	Q13976	PRKG1	S218	I215K	215	Missense	distal	-3	no	1.878	8.027	EPSD	GDSC;CCLE	7.092	Gain
AGC_PKG_PRKG1_ST	Q05469	LIPE	Q13976	PRKG1	S853	S855F	855	Missense	proximal	2	no	9.831	9.755	PhosphoSitePlus	GDSC;CCLE	7.092	Down-regulation
AGC_PKG_PRKG1_ST	Q05469	LIPE	Q13976	PRKG1	S855	S855F	855	Missense	central	0	yes	9.844	0.000	EPSD	GDSC;CCLE	7.092	Loss
AGC_PKG_PRKG1_ST	Q05469	LIPE	Q13976	PRKG1	S855	P862R	862	Missense	distal	7	no	9.844	9.985	EPSD	GDSC;CCLE	7.092	Up-regulation
AGC_PKG_PRKG1_ST	P41220	RGS2	Q13976	PRKG1	S46	R44H	44	Missense	proximal	-2	no	9.681	5.424	PhosphoSitePlus;EPSD	GDSC	7.092	Loss
AGC_PKG_PRKG1_ST	P41220	RGS2	Q13976	PRKG1	S179	E182*	182	Missense	distal	3	no	9.865	9.909	EPSD	GDSC	7.092	Up-regulation
AGC_PKG_PRKG1_ST	P31645	SLC6A4	Q13976	PRKG1	S13	A14V	14	Missense	proximal	1	no	8.019	7.697	EPSD	GDSC;CCLE	7.092	Down-regulation
AGC_PKG_PRKG1_ST	P31645	SLC6A4	Q13976	PRKG1	S44	N45S	45	Missense	proximal	1	no	7.975	8.179	EPSD	GDSC;CCLE	7.092	Up-regulation
AGC_PKG_PRKG1_ST	P31645	SLC6A4	Q13976	PRKG1	S44	S48L	48	Missense	distal	4	no	7.975	8.225	EPSD	GDSC;CCLE	7.092	Up-regulation
AGC_PKG_PRKG1_ST	Q13976	PRKG1	Q13976	PRKG1	S27	Q34E	34	Missense	distal	7	no	10.846	10.762	EPSD	GDSC	7.092	Down-regulation
AGC_PKG_PRKG1_ST	Q15052	ARHGEF6	Q13976	PRKG1	S123	R121H	121	Missense	proximal	-2	no	9.021	4.764	EPSD	GDSC	7.092	Loss
AGC_PKG_PRKG1_ST	Q15052	ARHGEF6	Q13976	PRKG1	S124	R121H	121	Missense	distal	-3	no	9.063	2.996	EPSD	GDSC	7.092	Loss
AGC_PKG_PRKG1_ST	Q15052	ARHGEF6	Q13976	PRKG1	S150	T152I	152	Missense	proximal	2	no	9.345	9.249	EPSD	GDSC;CCLE	7.092	Down-regulation
AGC_PKG_PRKG1_ST	Q15052	ARHGEF6	Q13976	PRKG1	S225	V229I	229	Missense	distal	4	no	10.936	10.997	EPSD	GDSC	7.092	Up-regulation
AGC_PKG_PRKG1_ST	Q15052	ARHGEF6	Q13976	PRKG1	S488	R486Q	486	Missense	proximal	-2	no	8.074	5.109	EPSD	GDSC;CCLE	7.092	Loss
AGC_PKG_PRKG1_ST	Q15052	ARHGEF6	Q13976	PRKG1	S640	E643*	643	Missense	distal	3	no	12.918	12.962	EPSD	GDSC	7.092	Up-regulation
AGC_PKG_PRKG1_ST	Q15052	ARHGEF6	Q13976	PRKG1	T650	E643*	643	Missense	distal	-7	no	7.923	7.790	EPSD	GDSC	7.092	Down-regulation
AGC_PKG_PRKG1_ST	Q15052	ARHGEF6	Q13976	PRKG1	T650	A652V	652	Missense	proximal	2	no	7.923	7.839	EPSD	GDSC;CCLE	7.092	Down-regulation
AGC_PKG_PRKG1_ST	Q15052	ARHGEF6	Q13976	PRKG1	S684	P686T	686	Missense	proximal	2	no	11.623	11.690	PhosphoSitePlus	GDSC;CCLE	7.092	Up-regulation
AGC_PKG_PRKG1_ST	Q76M96	CCDC80	Q13976	PRKG1	S134	P133L	133	Missense	proximal	-1	no	10.300	10.202	EPSD	GDSC;CCLE	7.092	Down-regulation
AGC_PKG_PRKG1_ST	Q76M96	CCDC80	Q13976	PRKG1	S305	S308G	308	Missense	distal	3	no	8.249	8.411	EPSD	GDSC	7.092	Up-regulation
AGC_PKG_PRKG1_ST	Q76M96	CCDC80	Q13976	PRKG1	S305	A301V	301	Missense	distal	-4	no	8.249	7.723	EPSD	GDSC;CCLE	7.092	Down-regulation
AGC_PKG_PRKG1_ST	Q76M96	CCDC80	Q13976	PRKG1	S305	G298*	298	Missense	distal	-7	no	8.249	7.798	EPSD	GDSC	7.092	Down-regulation
AGC_PKG_PRKG1_ST	Q76M96	CCDC80	Q13976	PRKG1	T352	T352P	352	Missense	central	0	yes	7.459	0.000	EPSD	GDSC	7.092	Loss
AGC_PKG_PRKG1_ST	Q76M96	CCDC80	Q13976	PRKG1	T352	T347P	347	Missense	distal	-5	no	7.459	7.565	EPSD	GDSC;CCLE	7.092	Up-regulation
AGC_PKG_PRKG1_ST	Q76M96	CCDC80	Q13976	PRKG1	T352	T351A	351	Missense	proximal	-1	no	7.459	7.454	EPSD	GDSC;CCLE	7.092	Down-regulation
AGC_PKG_PRKG1_ST	Q76M96	CCDC80	Q13976	PRKG1	T352	T351P	351	Missense	proximal	-1	no	7.459	7.357	EPSD	GDSC	7.092	Down-regulation
AGC_PKG_PRKG1_ST	Q76M96	CCDC80	Q13976	PRKG1	S366	V371D	371	Missense	distal	5	no	10.079	10.075	EPSD	GDSC;CCLE	7.092	Down-regulation
AGC_PKG_PRKG1_ST	Q76M96	CCDC80	Q13976	PRKG1	S409	R406G	406	Missense	distal	-3	no	12.972	8.382	EPSD;PhosphoSitePlus	GDSC;CCLE	7.092	Down-regulation
AGC_PKG_PRKG1_ST	Q76M96	CCDC80	Q13976	PRKG1	S409	A405S	405	Missense	distal	-4	no	12.972	12.976	EPSD;PhosphoSitePlus	GDSC;CCLE	7.092	Up-regulation
AGC_PKG_PRKG1_ST	Q76M96	CCDC80	Q13976	PRKG1	S572	Q578H	578	Missense	distal	6	no	7.760	7.870	EPSD	GDSC;CCLE	7.092	Up-regulation
AGC_PKG_PRKG1_ST	Q76M96	CCDC80	Q13976	PRKG1	S611	G617A	617	Missense	distal	6	no	7.178	7.067	EPSD	GDSC	7.092	Loss
CMGC_MAPK_ERK1_MAPK1_ST	P19634	SLC9A1	P28482	MAPK1	T68	R72H	72	Missense	distal	4	no	13.700	13.558	EPSD	GDSC;CCLE	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P19634	SLC9A1	P28482	MAPK1	S693	P694L	694	Missense	proximal	1	no	14.394	5.584	EPSD;PhosphoSitePlus	GDSC;CCLE	8.102	Loss
CMGC_MAPK_ERK1_MAPK1_ST	P19634	SLC9A1	P28482	MAPK1	S723	P724L	724	Missense	proximal	1	no	17.354	8.544	EPSD;PhosphoSitePlus	GDSC;CCLE	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P19634	SLC9A1	P28482	MAPK1	S726	P724L	724	Missense	proximal	-2	no	16.735	14.818	EPSD;PhosphoSitePlus	GDSC;CCLE	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P11388	TOP2A	P28482	MAPK1	S230	L231P	231	Missense	proximal	1	no	1.274	10.084	EPSD	GDSC;CCLE	8.102	Gain
CMGC_MAPK_ERK1_MAPK1_ST	P11388	TOP2A	P28482	MAPK1	T950	L944S	944	Missense	distal	-6	no	14.257	14.323	EPSD	GDSC;CCLE	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P11388	TOP2A	P28482	MAPK1	S1213	G1216C	1216	Missense	distal	3	no	13.923	14.012	EPSD;PhosphoSitePlus	GDSC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P11388	TOP2A	P28482	MAPK1	S1354	S1361F	1361	Missense	distal	7	no	14.705	15.052	EPSD;PhosphoSitePlus	GDSC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P11388	TOP2A	P28482	MAPK1	S1361	S1361F	1361	Missense	central	0	yes	15.536	0.000	PhosphoSitePlus;EPSD	GDSC	8.102	Loss
CMGC_MAPK_ERK1_MAPK1_ST	P11388	TOP2A	P28482	MAPK1	S1393	S1392*	1392	Missense	proximal	-1	no	10.974	10.907	EPSD;PhosphoSitePlus	GDSC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P11388	TOP2A	P28482	MAPK1	T1427	S1428P	1428	Missense	proximal	1	no	5.236	14.631	EPSD	GDSC;CCLE	8.102	Gain
CMGC_MAPK_ERK1_MAPK1_ST	O00562	PITPNM1	P28482	MAPK1	T287	A281E	281	Missense	distal	-6	no	15.406	15.456	EPSD	GDSC;CCLE	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	O00562	PITPNM1	P28482	MAPK1	S621	P624L	624	Missense	distal	3	no	14.648	14.738	EPSD	GDSC;CCLE	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	O00562	PITPNM1	P28482	MAPK1	S621	G618C	618	Missense	distal	-3	no	14.648	14.133	EPSD	GDSC;CCLE	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	O00562	PITPNM1	P28482	MAPK1	S638	I632V	632	Missense	distal	-6	no	14.568	14.609	EPSD	GDSC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	O00562	PITPNM1	P28482	MAPK1	S638	Q645R	645	Missense	distal	7	no	14.568	14.453	EPSD	GDSC;CCLE	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	O00562	PITPNM1	P28482	MAPK1	S638	E642D	642	Missense	distal	4	no	14.568	14.498	EPSD	GDSC;CCLE	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P15056	BRAF	P28482	MAPK1	S76	S76P	76	Missense	central	0	yes	8.648	0.000	EPSD	GDSC;CCLE	8.102	Loss
CMGC_MAPK_ERK1_MAPK1_ST	P15056	BRAF	P28482	MAPK1	S151	R146Q	146	Missense	distal	-5	no	15.658	15.736	EPSD	GDSC;CCLE	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P15056	BRAF	P28482	MAPK1	S317	A320S	320	Missense	distal	3	no	13.415	13.406	EPSD	GDSC;CCLE	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P15056	BRAF	P28482	MAPK1	S319	A320S	320	Missense	proximal	1	no	8.527	6.762	EPSD	GDSC;CCLE	8.102	Loss
CMGC_MAPK_ERK1_MAPK1_ST	P15056	BRAF	P28482	MAPK1	S323	A320S	320	Missense	distal	-3	no	9.556	9.747	EPSD	GDSC;CCLE	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P15056	BRAF	P28482	MAPK1	T401	A400V	400	Missense	proximal	-1	no	14.262	14.273	PhosphoSitePlus;EPSD	GDSC;CCLE	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P15056	BRAF	P28482	MAPK1	S750	A747V	747	Missense	distal	-3	no	14.197	14.257	EPSD	GDSC;CCLE	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P15056	BRAF	P28482	MAPK1	T753	A747V	747	Missense	distal	-6	no	19.816	19.769	EPSD;PhosphoSitePlus	GDSC;CCLE	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P15056	BRAF	P28482	MAPK1	T753	G759*	759	Missense	distal	6	no	19.816	19.130	EPSD;PhosphoSitePlus	GDSC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P04626	ERBB2	P28482	MAPK1	S1151	P1149S	1149	Missense	proximal	-2	no	16.299	13.465	EPSD	GDSC;CCLE	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P36956	SREBF1	P28482	MAPK1	T105	P99T	99	Missense	distal	-6	no	13.491	13.442	EPSD	GDSC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P36956	SREBF1	P28482	MAPK1	S386	L387P	387	Missense	proximal	1	no	4.462	13.272	EPSD	GDSC	8.102	Gain
CMGC_MAPK_ERK1_MAPK1_ST	P10636	MAPT	P28482	MAPK1	S46	Q49H	49	Missense	distal	3	no	14.520	14.541	EPSD;PhosphoSitePlus	GDSC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P10636	MAPT	P28482	MAPK1	S46	A41V	41	Missense	distal	-5	no	14.520	14.491	EPSD;PhosphoSitePlus	GDSC;CCLE	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P10636	MAPT	P28482	MAPK1	T50	Q49H	49	Missense	proximal	-1	no	16.282	16.280	EPSD;PhosphoSitePlus	GDSC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P10636	MAPT	P28482	MAPK1	S228	R222H	222	Missense	distal	-6	no	14.224	14.141	EPSD	GDSC;CCLE	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P10636	MAPT	P28482	MAPK1	T470	A475V	475	Missense	distal	5	no	14.781	14.798	EPSD	GDSC;CCLE	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P10636	MAPT	P28482	MAPK1	S739	S739C	739	Missense	central	0	yes	18.678	0.000	EPSD	GDSC	8.102	Loss
CMGC_MAPK_ERK1_MAPK1_ST	P10636	MAPT	P28482	MAPK1	T744	S739C	739	Missense	distal	-5	no	8.265	8.468	EPSD	GDSC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q13541	EIF4EBP1	P28482	MAPK1	S65	P66T	66	Missense	proximal	1	no	13.530	5.031	PhosphoSitePlus;EPSD	GDSC	8.102	Loss
CMGC_MAPK_ERK1_MAPK1_ST	Q13541	EIF4EBP1	P28482	MAPK1	T70	P66T	66	Missense	distal	-4	no	14.934	14.621	EPSD;PhosphoSitePlus	GDSC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q13541	EIF4EBP1	P28482	MAPK1	S101	G108S	108	Missense	distal	7	no	15.740	15.671	EPSD	GDSC;CCLE	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q13541	EIF4EBP1	P28482	MAPK1	S112	G108S	108	Missense	distal	-4	no	8.221	8.488	EPSD	GDSC;CCLE	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P50548	ERF	P28482	MAPK1	T3	P4L	4	Missense	proximal	1	no	12.254	3.444	EPSD	GDSC;CCLE	8.102	Loss
CMGC_MAPK_ERK1_MAPK1_ST	P50548	ERF	P28482	MAPK1	S21	P22L	22	Missense	proximal	1	no	16.292	7.483	EPSD	GDSC;CCLE	8.102	Loss
CMGC_MAPK_ERK1_MAPK1_ST	P50548	ERF	P28482	MAPK1	S24	P22L	22	Missense	proximal	-2	no	8.535	6.617	EPSD	GDSC;CCLE	8.102	Loss
CMGC_MAPK_ERK1_MAPK1_ST	P50548	ERF	P28482	MAPK1	S131	A132P	132	Missense	proximal	1	no	8.784	16.414	EPSD	GDSC;CCLE	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P50548	ERF	P28482	MAPK1	S131	A132S	132	Missense	proximal	1	no	8.784	7.019	EPSD	GDSC;CCLE	8.102	Loss
CMGC_MAPK_ERK1_MAPK1_ST	P50548	ERF	P28482	MAPK1	T148	F144L	144	Missense	distal	-4	no	15.729	15.770	EPSD	GDSC;CCLE	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P50548	ERF	P28482	MAPK1	T357	M353V	353	Missense	distal	-4	no	15.376	15.487	EPSD	GDSC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P50548	ERF	P28482	MAPK1	S373	P374Q	374	Missense	proximal	1	no	13.314	4.821	EPSD	GDSC	8.102	Loss
CMGC_MAPK_ERK1_MAPK1_ST	P50548	ERF	P28482	MAPK1	S373	F375L	375	Missense	proximal	2	no	13.314	13.326	EPSD	GDSC;CCLE	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P50548	ERF	P28482	MAPK1	S431	S431L	431	Missense	central	0	yes	8.731	0.000	EPSD	GDSC;CCLE	8.102	Loss
CMGC_MAPK_ERK1_MAPK1_ST	P50548	ERF	P28482	MAPK1	S431	E432D	432	Missense	proximal	1	no	8.731	8.806	EPSD	GDSC;CCLE	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P50548	ERF	P28482	MAPK1	T456	R458G	458	Missense	proximal	2	no	13.659	13.564	EPSD	GDSC;CCLE	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P49790	NUP153	P28482	MAPK1	T102	A106T	106	Missense	distal	4	no	13.100	13.080	EPSD	GDSC;CCLE	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P49790	NUP153	P28482	MAPK1	S320	K317N	317	Missense	distal	-3	no	14.053	14.150	EPSD;PhosphoSitePlus	GDSC;CCLE	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P49790	NUP153	P28482	MAPK1	T413	E409G	409	Missense	distal	-4	no	13.522	13.201	EPSD;PhosphoSitePlus	GDSC;CCLE	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P49790	NUP153	P28482	MAPK1	S500	A507V	507	Missense	distal	7	no	14.210	14.312	EPSD	GDSC;CCLE	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P49790	NUP153	P28482	MAPK1	S614	D610A	610	Missense	distal	-4	no	14.401	14.122	EPSD	GDSC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P49790	NUP153	P28482	MAPK1	S687	A680T	680	Missense	distal	-7	no	12.931	12.916	EPSD	GDSC;CCLE	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P49790	NUP153	P28482	MAPK1	T747	C742Y	742	Missense	distal	-5	no	12.493	12.421	EPSD	GDSC;CCLE	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P49790	NUP153	P28482	MAPK1	T747	V754M	754	Missense	distal	7	no	12.493	12.570	EPSD	GDSC;CCLE	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P49790	NUP153	P28482	MAPK1	T996	S994C	994	Missense	proximal	-2	no	11.873	10.940	EPSD	GDSC;CCLE	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P49790	NUP153	P28482	MAPK1	T1032	T1032I	1032	Missense	central	0	yes	12.934	0.000	EPSD	GDSC;CCLE	8.102	Loss
CMGC_MAPK_ERK1_MAPK1_ST	P49790	NUP153	P28482	MAPK1	T1032	I1039M	1039	Missense	distal	7	no	12.934	12.746	EPSD	GDSC;CCLE	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q16690	DUSP5	P28482	MAPK1	T321	T321M	321	Missense	central	0	yes	15.882	0.000	EPSD;PhosphoSitePlus	GDSC;CCLE	8.102	Loss
CMGC_MAPK_ERK1_MAPK1_ST	O95863	SNAI1	P28482	MAPK1	S104	S111L	111	Missense	distal	7	no	18.403	18.692	PhosphoSitePlus;EPSD	GDSC;CCLE	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	O95863	SNAI1	P28482	MAPK1	S107	S111L	111	Missense	distal	4	no	18.336	18.227	EPSD	GDSC;CCLE	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	O95863	SNAI1	P28482	MAPK1	S112	S111L	111	Missense	proximal	-1	no	10.083	10.066	EPSD	GDSC;CCLE	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P35568	IRS1	P28482	MAPK1	S362	R364W	364	Missense	proximal	2	no	8.870	8.502	EPSD	GDSC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P35568	IRS1	P28482	MAPK1	S362	P368A	368	Missense	distal	6	no	8.870	8.574	EPSD	GDSC;CCLE	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P35568	IRS1	P28482	MAPK1	S383	R381C	381	Missense	proximal	-2	no	15.450	13.502	EPSD	GDSC;CCLE	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P35568	IRS1	P28482	MAPK1	S383	A386S	386	Missense	distal	3	no	15.450	15.441	EPSD	GDSC;CCLE	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P35568	IRS1	P28482	MAPK1	S383	P376L	376	Missense	distal	-7	no	15.450	15.438	EPSD	GDSC;CCLE	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P35568	IRS1	P28482	MAPK1	S388	R381C	381	Missense	distal	-7	no	13.356	13.324	EPSD	GDSC;CCLE	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P35568	IRS1	P28482	MAPK1	S388	A386S	386	Missense	proximal	-2	no	13.356	13.668	EPSD	GDSC;CCLE	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P35568	IRS1	P28482	MAPK1	T495	G488S	488	Missense	distal	-7	no	15.028	15.042	EPSD	GDSC;CCLE	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P35568	IRS1	P28482	MAPK1	S636	A642S	642	Missense	distal	6	no	15.895	16.192	PhosphoSitePlus;EPSD	GDSC;CCLE	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P35568	IRS1	P28482	MAPK1	S639	A642S	642	Missense	distal	3	no	8.312	8.303	EPSD;PhosphoSitePlus	GDSC;CCLE	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P35568	IRS1	P28482	MAPK1	S736	P737S	737	Missense	proximal	1	no	13.268	3.873	EPSD	GDSC	8.102	Loss
CMGC_MAPK_ERK1_MAPK1_ST	P35568	IRS1	P28482	MAPK1	S1078	S1084R	1084	Missense	distal	6	no	12.871	12.764	EPSD	GDSC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P35568	IRS1	P28482	MAPK1	S1078	A1085D	1085	Missense	distal	7	no	12.871	12.686	EPSD	GDSC;CCLE	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P35568	IRS1	P28482	MAPK1	T1196	P1192L	1192	Missense	distal	-4	no	14.980	14.676	EPSD	GDSC;CCLE	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P35568	IRS1	P28482	MAPK1	S1217	S1218P	1218	Missense	proximal	1	no	5.626	15.021	EPSD	GDSC	8.102	Gain
CMGC_MAPK_ERK1_MAPK1_ST	P35568	IRS1	P28482	MAPK1	S1222	S1218P	1218	Missense	distal	-4	no	8.279	8.363	EPSD	GDSC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P35568	IRS1	P28482	MAPK1	S1223	S1218P	1218	Missense	distal	-5	no	8.399	8.325	EPSD	GDSC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P35568	IRS1	P28482	MAPK1	S1227	S1233N	1233	Missense	distal	6	no	9.189	9.092	EPSD	GDSC;CCLE	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	O00213	APBB1	P28482	MAPK1	S287	S287C	287	Missense	central	0	yes	17.229	0.000	EPSD;PhosphoSitePlus	GDSC;CCLE	8.102	Loss
CMGC_MAPK_ERK1_MAPK1_ST	O00213	APBB1	P28482	MAPK1	S287	S292I	292	Missense	distal	5	no	17.229	16.912	EPSD;PhosphoSitePlus	GDSC;CCLE	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	O00213	APBB1	P28482	MAPK1	S347	E354*	354	Missense	distal	7	no	15.884	16.452	EPSD;PhosphoSitePlus	GDSC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P49023	PXN	P28482	MAPK1	S85	S83F	83	Missense	proximal	-2	no	13.327	13.521	EPSD	GDSC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P49023	PXN	P28482	MAPK1	S85	V87E	87	Missense	proximal	2	no	13.327	13.314	EPSD	GDSC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P49023	PXN	P28482	MAPK1	S130	P129L	129	Missense	proximal	-1	no	14.828	14.769	EPSD;PhosphoSitePlus	GDSC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P49023	PXN	P28482	MAPK1	S188	G191R	191	Missense	distal	3	no	14.683	14.645	EPSD	GDSC;CCLE	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P49023	PXN	P28482	MAPK1	S188	S188R	188	Missense	central	0	yes	14.683	0.000	EPSD	GDSC	8.102	Loss
CMGC_MAPK_ERK1_MAPK1_ST	P49023	PXN	P28482	MAPK1	S303	R301G	301	Missense	proximal	-2	no	15.302	13.927	EPSD	GDSC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P49023	PXN	P28482	MAPK1	S303	S302G	302	Missense	proximal	-1	no	15.302	15.291	EPSD	GDSC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P49023	PXN	P28482	MAPK1	S303	G305R	305	Missense	proximal	2	no	15.302	15.397	EPSD	GDSC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P49023	PXN	P28482	MAPK1	S322	S321N	321	Missense	proximal	-1	no	11.412	11.461	EPSD	GDSC;CCLE	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P38936	CDKN1A	P28482	MAPK1	T57	E56*	56	Missense	proximal	-1	no	13.731	13.636	EPSD;PhosphoSitePlus	GDSC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P15336	ATF2	P28482	MAPK1	T69	V63A	63	Missense	distal	-6	no	13.621	13.668	EPSD	GDSC;CCLE	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P15336	ATF2	P28482	MAPK1	S136	Q134H	134	Missense	proximal	-2	no	14.697	14.936	EPSD	GDSC;CCLE	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P15336	ATF2	P28482	MAPK1	T325	H331L	331	Missense	distal	6	no	13.109	13.008	EPSD	GDSC;CCLE	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P15336	ATF2	P28482	MAPK1	S328	H331L	331	Missense	distal	3	no	17.310	17.311	EPSD	GDSC;CCLE	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P15336	ATF2	P28482	MAPK1	T333	H331L	331	Missense	proximal	-2	no	14.496	15.334	EPSD	GDSC;CCLE	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P23443	RPS6KB1	P28482	MAPK1	S503	P505L	505	Missense	proximal	2	no	10.561	10.414	EPSD	GDSC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q92934	BAD	P28482	MAPK1	S25	D29N	29	Missense	distal	4	no	16.358	16.417	EPSD	GDSC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q92934	BAD	P28482	MAPK1	S124	L129F	129	Missense	distal	5	no	8.838	8.872	EPSD	GDSC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q92934	BAD	P28482	MAPK1	S134	T137K	137	Missense	distal	3	no	8.841	8.776	EPSD	GDSC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q92934	BAD	P28482	MAPK1	S134	L129F	129	Missense	distal	-5	no	8.841	8.854	EPSD	GDSC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q92934	BAD	P28482	MAPK1	S146	F151L	151	Missense	distal	5	no	8.396	8.362	EPSD	GDSC;CCLE	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q92934	BAD	P28482	MAPK1	S153	F151L	151	Missense	proximal	-2	no	8.934	9.657	EPSD	GDSC;CCLE	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q9GZM8	NDEL1	P28482	MAPK1	S331	S332L	332	Missense	proximal	1	no	9.062	9.647	EPSD	GDSC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q9GZM8	NDEL1	P28482	MAPK1	S336	S332L	332	Missense	distal	-4	no	12.479	12.258	EPSD	GDSC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q9GZM8	NDEL1	P28482	MAPK1	S344	P342S	342	Missense	proximal	-2	no	8.706	5.872	EPSD	GDSC	8.102	Loss
CMGC_MAPK_ERK1_MAPK1_ST	Q07343	PDE4B	P28482	MAPK1	T167	A174D	174	Missense	distal	7	no	14.341	14.156	EPSD	GDSC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q07343	PDE4B	P28482	MAPK1	S290	V286M	286	Missense	distal	-4	no	13.483	13.371	EPSD	GDSC;CCLE	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q07343	PDE4B	P28482	MAPK1	S659	P662A	662	Missense	distal	3	no	17.106	17.184	PhosphoSitePlus;EPSD	GDSC;CCLE	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q07343	PDE4B	P28482	MAPK1	S661	N668K	668	Missense	distal	7	no	12.819	12.785	EPSD	GDSC;CCLE	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q07343	PDE4B	P28482	MAPK1	S661	P662A	662	Missense	proximal	1	no	12.819	5.189	EPSD	GDSC;CCLE	8.102	Loss
CMGC_MAPK_ERK1_MAPK1_ST	Q9H8Y8	GORASP2	P28482	MAPK1	S245	G248E	248	Missense	distal	3	no	13.653	13.560	EPSD	GDSC;CCLE	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q9H8Y8	GORASP2	P28482	MAPK1	T249	G248E	248	Missense	proximal	-1	no	8.553	8.592	EPSD	GDSC;CCLE	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q9H8Y8	GORASP2	P28482	MAPK1	T433	P434A	434	Missense	proximal	1	no	15.171	7.541	EPSD	GDSC;CCLE	8.102	Loss
CMGC_MAPK_ERK1_MAPK1_ST	Q9H8Y8	GORASP2	P28482	MAPK1	S436	P434A	434	Missense	proximal	-2	no	10.147	7.000	EPSD	GDSC;CCLE	8.102	Loss
CMGC_MAPK_ERK1_MAPK1_ST	Q9H8Y8	GORASP2	P28482	MAPK1	S441	P434A	434	Missense	distal	-7	no	11.560	11.558	EPSD	GDSC;CCLE	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P19793	RXRA	P28482	MAPK1	S21	R25*	25	Missense	distal	4	no	16.365	16.086	EPSD	GDSC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P19793	RXRA	P28482	MAPK1	S21	P22L	22	Missense	proximal	1	no	16.365	7.555	EPSD	GDSC	8.102	Loss
CMGC_MAPK_ERK1_MAPK1_ST	P19793	RXRA	P28482	MAPK1	S66	S66L	66	Missense	central	0	yes	8.522	0.000	EPSD	GDSC;CCLE	8.102	Loss
CMGC_MAPK_ERK1_MAPK1_ST	Q8WX93	PALLD	P28482	MAPK1	S71	S71Y	71	Missense	central	0	yes	13.470	0.000	EPSD	GDSC;CCLE	8.102	Loss
CMGC_MAPK_ERK1_MAPK1_ST	Q8WX93	PALLD	P28482	MAPK1	T100	T100K	100	Missense	central	0	yes	14.453	0.000	EPSD	GDSC;CCLE	8.102	Loss
CMGC_MAPK_ERK1_MAPK1_ST	Q8WX93	PALLD	P28482	MAPK1	S115	S118*	118	Missense	distal	3	no	14.813	14.896	EPSD	GDSC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q8WX93	PALLD	P28482	MAPK1	S125	S118*	118	Missense	distal	-7	no	12.744	12.718	EPSD	GDSC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q8WX93	PALLD	P28482	MAPK1	T147	E141K	141	Missense	distal	-6	no	10.837	10.811	EPSD	GDSC;CCLE	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q8WX93	PALLD	P28482	MAPK1	S192	P193L	193	Missense	proximal	1	no	10.428	1.618	EPSD	GDSC;CCLE	8.102	Loss
CMGC_MAPK_ERK1_MAPK1_ST	Q8WX93	PALLD	P28482	MAPK1	S192	S199P	199	Missense	distal	7	no	10.428	10.417	EPSD	GDSC;CCLE	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q8WX93	PALLD	P28482	MAPK1	S198	S199P	199	Missense	proximal	1	no	5.156	14.551	EPSD	GDSC;CCLE	8.102	Gain
CMGC_MAPK_ERK1_MAPK1_ST	Q8WX93	PALLD	P28482	MAPK1	S199	P193L	193	Missense	distal	-6	no	12.436	12.344	EPSD	GDSC;CCLE	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q8WX93	PALLD	P28482	MAPK1	S199	S199P	199	Missense	central	0	yes	12.436	0.000	EPSD	GDSC;CCLE	8.102	Loss
CMGC_MAPK_ERK1_MAPK1_ST	Q8WX93	PALLD	P28482	MAPK1	S206	S199P	199	Missense	distal	-7	no	14.383	14.388	EPSD	GDSC;CCLE	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q8WX93	PALLD	P28482	MAPK1	S484	D486Y	486	Missense	proximal	2	no	12.366	12.186	EPSD	GDSC;CCLE	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q13127	REST	P28482	MAPK1	S734	V739M	739	Missense	distal	5	no	13.489	13.427	EPSD	GDSC;CCLE	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q13127	REST	P28482	MAPK1	S750	V755M	755	Missense	distal	5	no	13.959	13.897	EPSD	GDSC;CCLE	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q13127	REST	P28482	MAPK1	S766	Q773H	773	Missense	distal	7	no	13.930	14.034	EPSD	GDSC;CCLE	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q13127	REST	P28482	MAPK1	S766	I763V	763	Missense	distal	-3	no	13.930	14.064	EPSD	GDSC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q13127	REST	P28482	MAPK1	S766	I769M	769	Missense	distal	3	no	13.930	13.888	EPSD	GDSC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q04637	EIF4G1	P28482	MAPK1	T43	Q37*	37	Missense	distal	-6	no	12.314	12.194	EPSD	GDSC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q04637	EIF4G1	P28482	MAPK1	S261	P264L	264	Missense	distal	3	no	16.539	16.629	EPSD	GDSC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q04637	EIF4G1	P28482	MAPK1	S263	P264L	264	Missense	proximal	1	no	14.971	6.161	EPSD	GDSC	8.102	Loss
CMGC_MAPK_ERK1_MAPK1_ST	Q04637	EIF4G1	P28482	MAPK1	T265	P264L	264	Missense	proximal	-1	no	14.574	14.514	EPSD	GDSC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q04637	EIF4G1	P28482	MAPK1	S267	P264L	264	Missense	distal	-3	no	13.257	12.874	EPSD	GDSC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q04637	EIF4G1	P28482	MAPK1	S269	S276C	276	Missense	distal	7	no	14.135	14.794	EPSD	GDSC;CCLE	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q04637	EIF4G1	P28482	MAPK1	S269	P264L	264	Missense	distal	-5	no	14.135	14.284	EPSD	GDSC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q04637	EIF4G1	P28482	MAPK1	S314	A321V	321	Missense	distal	7	no	13.497	13.598	EPSD	GDSC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q04637	EIF4G1	P28482	MAPK1	S314	R312C	312	Missense	proximal	-2	no	13.497	11.549	EPSD	GDSC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q04637	EIF4G1	P28482	MAPK1	T318	A321V	321	Missense	distal	3	no	13.616	13.595	EPSD	GDSC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q04637	EIF4G1	P28482	MAPK1	T318	R312C	312	Missense	distal	-6	no	13.616	13.441	EPSD	GDSC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q04637	EIF4G1	P28482	MAPK1	S488	P486S	486	Missense	proximal	-2	no	9.515	6.681	EPSD	GDSC	8.102	Loss
CMGC_MAPK_ERK1_MAPK1_ST	Q04637	EIF4G1	P28482	MAPK1	T489	P486S	486	Missense	distal	-3	no	12.777	12.601	EPSD	GDSC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q04637	EIF4G1	P28482	MAPK1	T1179	D1175V	1175	Missense	distal	-4	no	14.265	13.925	EPSD	GDSC;CCLE	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q04637	EIF4G1	P28482	MAPK1	S1271	L1275H	1275	Missense	distal	4	no	13.949	13.894	EPSD	GDSC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q04637	EIF4G1	P28482	MAPK1	T1495	R1498Q	1498	Missense	distal	3	no	12.289	12.311	EPSD	GDSC;CCLE	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q13586	STIM1	P28482	MAPK1	S486	V485M	485	Missense	proximal	-1	no	14.681	14.657	EPSD	GDSC;CCLE	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q13586	STIM1	P28482	MAPK1	S492	V485M	485	Missense	distal	-7	no	13.552	13.549	EPSD	GDSC;CCLE	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q13586	STIM1	P28482	MAPK1	S608	R615C	615	Missense	distal	7	no	14.620	15.275	PhosphoSitePlus;EPSD	GDSC;CCLE	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q13586	STIM1	P28482	MAPK1	S618	R615C	615	Missense	distal	-3	no	15.649	14.966	EPSD	GDSC;CCLE	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q13586	STIM1	P28482	MAPK1	S621	R615C	615	Missense	distal	-6	no	17.201	17.026	EPSD;PhosphoSitePlus	GDSC;CCLE	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q13586	STIM1	P28482	MAPK1	S621	T626I	626	Missense	distal	5	no	17.201	16.957	EPSD;PhosphoSitePlus	GDSC;CCLE	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q13586	STIM1	P28482	MAPK1	T626	T626I	626	Missense	central	0	yes	15.638	0.000	EPSD	GDSC;CCLE	8.102	Loss
CMGC_MAPK_ERK1_MAPK1_ST	Q13586	STIM1	P28482	MAPK1	S628	T626I	626	Missense	proximal	-2	no	15.060	15.865	EPSD	GDSC;CCLE	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q02224	CENPE	P28482	MAPK1	S2605	V2611M	2611	Missense	distal	6	no	14.093	13.875	EPSD;PhosphoSitePlus	GDSC;CCLE	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q02224	CENPE	P28482	MAPK1	S2608	V2611M	2611	Missense	distal	3	no	15.650	15.678	EPSD;PhosphoSitePlus	GDSC;CCLE	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q02224	CENPE	P28482	MAPK1	T2622	E2628D	2628	Missense	distal	6	no	13.092	13.013	EPSD	GDSC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q02224	CENPE	P28482	MAPK1	S2639	C2643F	2643	Missense	distal	4	no	15.002	15.106	PhosphoSitePlus;EPSD	GDSC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q02224	CENPE	P28482	MAPK1	S2642	C2643F	2643	Missense	proximal	1	no	3.775	10.654	EPSD	GDSC	8.102	Gain
CMGC_MAPK_ERK1_MAPK1_ST	P50616	TOB1	P28482	MAPK1	S152	H159Y	159	Missense	distal	7	no	13.582	13.877	EPSD;PhosphoSitePlus	GDSC;CCLE	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P50616	TOB1	P28482	MAPK1	S154	H159Y	159	Missense	distal	5	no	15.193	15.049	PhosphoSitePlus;EPSD	GDSC;CCLE	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P50616	TOB1	P28482	MAPK1	S164	H159Y	159	Missense	distal	-5	no	14.103	14.183	EPSD;PhosphoSitePlus	GDSC;CCLE	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P49815	TSC2	P28482	MAPK1	S960	V963M	963	Missense	distal	3	no	11.546	11.574	EPSD	GDSC;CCLE	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P49815	TSC2	P28482	MAPK1	S1045	P1042R	1042	Missense	distal	-3	no	14.811	14.792	EPSD	GDSC;CCLE	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P49815	TSC2	P28482	MAPK1	S1155	R1159W	1159	Missense	distal	4	no	14.127	13.844	EPSD	GDSC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P49815	TSC2	P28482	MAPK1	S1411	S1411R	1411	Missense	central	0	yes	15.321	0.000	EPSD	GDSC;CCLE	8.102	Loss
CMGC_MAPK_ERK1_MAPK1_ST	P10415	BCL2	P28482	MAPK1	T56	P59T	59	Missense	distal	3	no	14.539	14.600	EPSD;PhosphoSitePlus	GDSC;CCLE	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P10415	BCL2	P28482	MAPK1	T56	H55P	55	Missense	proximal	-1	no	14.539	14.581	EPSD;PhosphoSitePlus	GDSC;CCLE	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q9NQ66	PLCB1	P28482	MAPK1	T39	I41F	41	Missense	proximal	2	no	15.441	15.452	EPSD	GDSC;CCLE	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q9NQ66	PLCB1	P28482	MAPK1	S387	V391L	391	Missense	distal	4	no	8.431	8.421	EPSD	GDSC;CCLE	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q9NQ66	PLCB1	P28482	MAPK1	S410	D416G	416	Missense	distal	6	no	9.459	9.427	EPSD	GDSC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q9NQ66	PLCB1	P28482	MAPK1	S410	E412Q	412	Missense	proximal	2	no	9.459	9.348	EPSD	GDSC;CCLE	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q9NQ66	PLCB1	P28482	MAPK1	S417	D416G	416	Missense	proximal	-1	no	16.300	16.301	EPSD	GDSC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q9NQ66	PLCB1	P28482	MAPK1	S417	E412Q	412	Missense	distal	-5	no	16.300	16.399	EPSD	GDSC;CCLE	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q9NQ66	PLCB1	P28482	MAPK1	S501	P502T	502	Missense	proximal	1	no	17.571	9.072	EPSD	GDSC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q9NQ66	PLCB1	P28482	MAPK1	S501	P502L	502	Missense	proximal	1	no	17.571	8.761	EPSD	GDSC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q15554	TERF2	P28482	MAPK1	T169	E172Q	172	Missense	distal	3	no	11.467	11.544	EPSD	GDSC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P17655	CAPN2	P28482	MAPK1	S50	A57S	57	Missense	distal	7	no	8.446	8.265	PhosphoSitePlus	GDSC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P17655	CAPN2	P28482	MAPK1	S67	E74K	74	Missense	distal	7	no	8.354	8.361	EPSD	GDSC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P30041	PRDX6	P28482	MAPK1	T44	T49R	49	Missense	distal	5	no	13.824	13.929	EPSD	GDSC;CCLE	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q9BY84	DUSP16	P28482	MAPK1	S501	L499R	499	Missense	proximal	-2	no	14.135	14.234	EPSD	GDSC;CCLE	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	O75030	MITF	P28482	MAPK1	T23	E26K	26	Missense	distal	3	no	10.611	10.618	EPSD	GDSC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	O75030	MITF	P28482	MAPK1	S175	P178R	178	Missense	distal	3	no	8.206	8.252	EPSD	GDSC;CCLE	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	O75030	MITF	P28482	MAPK1	S180	P178R	178	Missense	proximal	-2	no	17.567	15.748	EPSD	GDSC;CCLE	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P03372	ESR1	P28482	MAPK1	S167	G160S	160	Missense	distal	-7	no	8.379	8.393	EPSD	GDSC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P03372	ESR1	P28482	MAPK1	S167	R164I	164	Missense	distal	-3	no	8.379	7.957	EPSD	GDSC;CCLE	8.102	Loss
CMGC_MAPK_ERK1_MAPK1_ST	P03372	ESR1	P28482	MAPK1	S294	K299N	299	Missense	distal	5	no	14.197	14.228	EPSD	GDSC;CCLE	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P03372	ESR1	P28482	MAPK1	S294	I298V	298	Missense	distal	4	no	14.197	14.264	EPSD	GDSC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q07889	SOS1	P28482	MAPK1	S1167	M1172I	1172	Missense	distal	5	no	14.128	14.016	EPSD;PhosphoSitePlus	GDSC;CCLE	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q07889	SOS1	P28482	MAPK1	S1178	M1172I	1172	Missense	distal	-6	no	13.573	13.529	EPSD;PhosphoSitePlus	GDSC;CCLE	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q07889	SOS1	P28482	MAPK1	S1210	R1217Q	1217	Missense	distal	7	no	17.240	17.356	EPSD	GDSC;CCLE	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q07889	SOS1	P28482	MAPK1	T1222	R1217Q	1217	Missense	distal	-5	no	14.025	14.103	EPSD	GDSC;CCLE	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q07889	SOS1	P28482	MAPK1	S1252	F1248C	1248	Missense	distal	-4	no	17.483	17.101	EPSD	GDSC;CCLE	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q07889	SOS1	P28482	MAPK1	S1254	F1248C	1248	Missense	distal	-6	no	14.219	14.163	EPSD	GDSC;CCLE	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q07889	SOS1	P28482	MAPK1	T1263	G1268S	1268	Missense	distal	5	no	18.139	18.159	EPSD	GDSC;CCLE	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q07889	SOS1	P28482	MAPK1	S1265	G1268S	1268	Missense	distal	3	no	15.480	15.466	EPSD	GDSC;CCLE	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q07889	SOS1	P28482	MAPK1	S1275	G1268S	1268	Missense	distal	-7	no	15.309	15.323	EPSD	GDSC;CCLE	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q07889	SOS1	P28482	MAPK1	T1309	T1309A	1309	Missense	central	0	yes	9.740	0.000	EPSD	GDSC;CCLE	8.102	Loss
CMGC_MAPK_ERK1_MAPK1_ST	Q07889	SOS1	P28482	MAPK1	T1309	P1306H	1306	Missense	distal	-3	no	9.740	9.391	EPSD	GDSC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q13614	MTMR2	P28482	MAPK1	S29	S29C	29	Missense	central	0	yes	8.462	0.000	EPSD	GDSC;CCLE	8.102	Loss
CMGC_MAPK_ERK1_MAPK1_ST	Q96EP5	DAZAP1	P28482	MAPK1	S208	R209W	209	Missense	proximal	1	no	6.098	8.376	EPSD	GDSC;CCLE	8.102	Gain
CMGC_MAPK_ERK1_MAPK1_ST	Q96EP5	DAZAP1	P28482	MAPK1	T315	A318T	318	Missense	distal	3	no	17.191	17.175	PhosphoSitePlus;EPSD	GDSC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q13322	GRB10	P28482	MAPK1	T23	Y16H	16	Missense	distal	-7	no	15.860	15.880	EPSD	GDSC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q13322	GRB10	P28482	MAPK1	T23	P30Q	30	Missense	distal	7	no	15.860	15.990	EPSD	GDSC;CCLE	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q13322	GRB10	P28482	MAPK1	S150	P152A	152	Missense	proximal	2	no	16.768	16.638	PhosphoSitePlus;EPSD	GDSC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q13322	GRB10	P28482	MAPK1	T155	P152A	152	Missense	distal	-3	no	12.625	12.258	EPSD	GDSC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q13322	GRB10	P28482	MAPK1	T155	P160T	160	Missense	distal	5	no	12.625	12.569	EPSD	GDSC;CCLE	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q13322	GRB10	P28482	MAPK1	T422	E429K	429	Missense	distal	7	no	13.463	13.471	EPSD	GDSC;CCLE	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q13322	GRB10	P28482	MAPK1	S476	P477L	477	Missense	proximal	1	no	13.998	5.188	EPSD;PhosphoSitePlus	GDSC;CCLE	8.102	Loss
CMGC_MAPK_ERK1_MAPK1_ST	Q13322	GRB10	P28482	MAPK1	S476	Q475*	475	Missense	proximal	-1	no	13.998	13.928	EPSD;PhosphoSitePlus	GDSC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P84022	SMAD3	P28482	MAPK1	T179	P172T	172	Missense	distal	-7	no	14.377	14.361	EPSD;PhosphoSitePlus	GDSC;CCLE	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P12980	LYL1	P28482	MAPK1	S260	R266G	266	Missense	distal	6	no	16.315	16.345	EPSD	GDSC;CCLE	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P12980	LYL1	P28482	MAPK1	S276	T273P	273	Missense	distal	-3	no	15.862	16.071	EPSD	GDSC;CCLE	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P12980	LYL1	P28482	MAPK1	S276	T273N	273	Missense	distal	-3	no	15.862	15.910	EPSD	GDSC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P51812	RPS6KA3	P28482	MAPK1	T577	T581I	581	Missense	distal	4	no	15.244	15.190	EPSD	GDSC;CCLE	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P51812	RPS6KA3	P28482	MAPK1	T625	E628D	628	Missense	distal	3	no	10.201	10.296	EPSD	GDSC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P08047	SP1	P28482	MAPK1	S59	A66G	66	Missense	distal	7	no	13.407	13.295	PhosphoSitePlus;EPSD	GDSC;CCLE	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P08047	SP1	P28482	MAPK1	S73	A66G	66	Missense	distal	-7	no	13.859	13.843	EPSD	GDSC;CCLE	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P08047	SP1	P28482	MAPK1	T739	T737A	737	Missense	proximal	-2	no	13.402	12.955	EPSD;PhosphoSitePlus	GDSC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P08047	SP1	P28482	MAPK1	T739	G736V	736	Missense	distal	-3	no	13.402	13.284	EPSD;PhosphoSitePlus	GDSC;CCLE	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P08047	SP1	P28482	MAPK1	T739	A738T	738	Missense	proximal	-1	no	13.402	13.397	EPSD;PhosphoSitePlus	GDSC;CCLE	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P55211	CASP9	P28482	MAPK1	T125	P123L	123	Missense	proximal	-2	no	15.221	13.304	PhosphoSitePlus	GDSC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P55211	CASP9	P28482	MAPK1	S302	E306K	306	Missense	distal	4	no	15.851	15.865	EPSD	GDSC;CCLE	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P55211	CASP9	P28482	MAPK1	S307	E306K	306	Missense	proximal	-1	no	12.776	12.804	EPSD	GDSC;CCLE	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q16828	DUSP6	P28482	MAPK1	S197	S202R	202	Missense	distal	5	no	14.950	14.982	EPSD;PhosphoSitePlus	GDSC;CCLE	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q16828	DUSP6	P28482	MAPK1	S205	S202R	202	Missense	distal	-3	no	8.150	8.306	EPSD	GDSC;CCLE	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	O94953	KDM4B	P28482	MAPK1	T185	T185A	185	Missense	central	0	yes	8.535	0.000	EPSD	GDSC;CCLE	8.102	Loss
CMGC_MAPK_ERK1_MAPK1_ST	Q15788	NCOA1	P28482	MAPK1	S16	S9F	9	Missense	distal	-7	no	12.301	12.281	EPSD	GDSC;CCLE	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q15788	NCOA1	P28482	MAPK1	S22	T26P	26	Missense	distal	4	no	15.676	15.799	EPSD	GDSC;CCLE	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q15788	NCOA1	P28482	MAPK1	S488	S482C	482	Missense	distal	-6	no	14.072	13.931	EPSD	GDSC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q15788	NCOA1	P28482	MAPK1	S488	I481T	481	Missense	distal	-7	no	14.072	14.087	EPSD	GDSC;CCLE	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q15788	NCOA1	P28482	MAPK1	T1026	T1020K	1020	Missense	distal	-6	no	14.567	14.602	EPSD	GDSC;CCLE	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q15788	NCOA1	P28482	MAPK1	T1179	P1180L	1180	Missense	proximal	1	no	16.029	7.220	PhosphoSitePlus;EPSD	GDSC;CCLE	8.102	Loss
CMGC_MAPK_ERK1_MAPK1_ST	Q15788	NCOA1	P28482	MAPK1	S1185	P1180L	1180	Missense	distal	-5	no	14.689	14.838	EPSD;PhosphoSitePlus	GDSC;CCLE	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q15788	NCOA1	P28482	MAPK1	T1426	G1423E	1423	Missense	distal	-3	no	19.438	19.447	EPSD	GDSC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q15788	NCOA1	P28482	MAPK1	T1426	S1422L	1422	Missense	distal	-4	no	19.438	19.218	EPSD	GDSC;CCLE	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P13591	NCAM1	P28482	MAPK1	T798	E794D	794	Missense	distal	-4	no	12.153	12.168	EPSD	GDSC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P15923	TCF3	P28482	MAPK1	S110	A109S	109	Missense	proximal	-1	no	9.107	9.101	EPSD	GDSC;CCLE	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P15923	TCF3	P28482	MAPK1	S529	K522Q	522	Missense	distal	-7	no	15.759	15.763	EPSD	GDSC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P15923	TCF3	P28482	MAPK1	S529	P524L	524	Missense	distal	-5	no	15.759	15.907	EPSD	GDSC;CCLE	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q96RK0	CIC	P28482	MAPK1	S191	N193D	193	Missense	proximal	2	no	14.663	14.723	EPSD	GDSC;CCLE	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q96RK0	CIC	P28482	MAPK1	S502	P509A	509	Missense	distal	7	no	7.916	8.108	EPSD	GDSC;CCLE	8.102	Gain
CMGC_MAPK_ERK1_MAPK1_ST	Q96RK0	CIC	P28482	MAPK1	T583	A587V	587	Missense	distal	4	no	16.950	16.944	EPSD	GDSC;CCLE	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q96RK0	CIC	P28482	MAPK1	S700	N702S	702	Missense	proximal	2	no	12.565	12.613	EPSD	GDSC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q96RK0	CIC	P28482	MAPK1	T704	N702S	702	Missense	proximal	-2	no	8.279	8.264	EPSD	GDSC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q96RK0	CIC	P28482	MAPK1	S1191	A1196T	1196	Missense	distal	5	no	8.179	8.265	EPSD	GDSC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q96RK0	CIC	P28482	MAPK1	T1318	R1321C	1321	Missense	distal	3	no	13.559	13.686	EPSD	GDSC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q96RK0	CIC	P28482	MAPK1	T1318	E1323V	1323	Missense	distal	5	no	13.559	13.460	EPSD	GDSC;CCLE	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q96RK0	CIC	P28482	MAPK1	S1373	S1378C	1378	Missense	distal	5	no	13.043	12.643	EPSD	GDSC;CCLE	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q96RK0	CIC	P28482	MAPK1	S1382	S1378C	1378	Missense	distal	-4	no	14.115	13.471	EPSD	GDSC;CCLE	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q92793	CREBBP	P28482	MAPK1	S93	G98V	98	Missense	distal	5	no	13.467	13.344	PhosphoSitePlus	GDSC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q92793	CREBBP	P28482	MAPK1	S306	L307F	307	Missense	proximal	1	no	6.068	8.308	EPSD	GDSC;CCLE	8.102	Gain
CMGC_MAPK_ERK1_MAPK1_ST	Q92793	CREBBP	P28482	MAPK1	T309	L307F	307	Missense	proximal	-2	no	8.161	7.438	EPSD	GDSC;CCLE	8.102	Loss
CMGC_MAPK_ERK1_MAPK1_ST	Q92793	CREBBP	P28482	MAPK1	S448	Q443*	443	Missense	distal	-5	no	15.318	15.474	EPSD	GDSC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q92793	CREBBP	P28482	MAPK1	S448	P449L	449	Missense	proximal	1	no	15.318	6.509	EPSD	GDSC;CCLE	8.102	Loss
CMGC_MAPK_ERK1_MAPK1_ST	Q92793	CREBBP	P28482	MAPK1	S745	G740E	740	Missense	distal	-5	no	16.277	16.235	EPSD	GDSC;CCLE	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q92793	CREBBP	P28482	MAPK1	S1763	S1761*	1761	Missense	proximal	-2	no	15.448	5.011	EPSD	GDSC	8.102	Loss
CMGC_MAPK_ERK1_MAPK1_ST	Q92793	CREBBP	P28482	MAPK1	S1763	R1769P	1769	Missense	distal	6	no	15.448	15.555	EPSD	GDSC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q92793	CREBBP	P28482	MAPK1	S1884	Q1879*	1879	Missense	distal	-5	no	14.906	15.062	EPSD	GDSC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P32121	ARRB2	P28482	MAPK1	S360	P363S	363	Missense	distal	3	no	11.077	11.146	EPSD	GDSC;CCLE	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q96RS0	TGS1	P28482	MAPK1	S189	P183L	183	Missense	distal	-6	no	13.150	13.058	EPSD	GDSC;CCLE	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q96RS0	TGS1	P28482	MAPK1	S578	E581K	581	Missense	distal	3	no	8.904	8.910	EPSD	GDSC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q01860	POU5F1	P28482	MAPK1	S355	M357T	357	Missense	proximal	2	no	17.620	17.760	EPSD;PhosphoSitePlus	GDSC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P49795	RGS19	P28482	MAPK1	S24	D18V	18	Missense	distal	-6	no	8.902	8.792	EPSD	GDSC;CCLE	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P49795	RGS19	P28482	MAPK1	S25	D18V	18	Missense	distal	-7	no	8.730	8.714	EPSD	GDSC;CCLE	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P49795	RGS19	P28482	MAPK1	T28	S35R	35	Missense	distal	7	no	8.654	8.657	EPSD	GDSC;CCLE	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P49795	RGS19	P28482	MAPK1	S30	S35R	35	Missense	distal	5	no	15.979	16.011	EPSD	GDSC;CCLE	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P49795	RGS19	P28482	MAPK1	S151	V147I	147	Missense	distal	-4	no	15.124	14.807	PhosphoSitePlus	GDSC;CCLE	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q8NHW3	MAFA	P28482	MAPK1	S325	S325G	325	Missense	central	0	yes	9.518	0.000	EPSD	GDSC	8.102	Loss
CMGC_MAPK_ERK1_MAPK1_ST	Q9BUB5	MKNK1	P28482	MAPK1	S460	T463I	463	Missense	distal	3	no	16.116	16.182	EPSD	GDSC;CCLE	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q9BUB5	MKNK1	P28482	MAPK1	S460	R455H	455	Missense	distal	-5	no	16.116	16.193	EPSD	GDSC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q9BUB5	MKNK1	P28482	MAPK1	T463	T463I	463	Missense	central	0	yes	8.107	0.000	EPSD	GDSC;CCLE	8.102	Loss
CMGC_MAPK_ERK1_MAPK1_ST	Q96FF9	CDCA5	P28482	MAPK1	S15	G16E	16	Missense	proximal	1	no	7.342	8.636	EPSD	GDSC	8.102	Gain
CMGC_MAPK_ERK1_MAPK1_ST	Q96FF9	CDCA5	P28482	MAPK1	S21	G16E	16	Missense	distal	-5	no	16.770	16.728	EPSD	GDSC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q96FF9	CDCA5	P28482	MAPK1	T111	P109S	109	Missense	proximal	-2	no	16.339	13.505	EPSD	GDSC;CCLE	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q96FF9	CDCA5	P28482	MAPK1	S114	P109S	109	Missense	distal	-5	no	9.833	9.907	EPSD	GDSC;CCLE	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q96FF9	CDCA5	P28482	MAPK1	T115	P109S	109	Missense	distal	-6	no	12.745	12.719	EPSD	GDSC;CCLE	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q96FF9	CDCA5	P28482	MAPK1	S209	P210Q	210	Missense	proximal	1	no	12.164	3.671	PhosphoSitePlus;EPSD	GDSC	8.102	Loss
CMGC_MAPK_ERK1_MAPK1_ST	P49137	MAPKAPK2	P28482	MAPK1	T222	Y225H	225	Missense	distal	3	no	17.205	17.167	EPSD;PhosphoSitePlus	GDSC;CCLE	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P49137	MAPKAPK2	P28482	MAPK1	T226	Y225H	225	Missense	proximal	-1	no	11.594	11.627	EPSD	GDSC;CCLE	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P23396	RPS3	P28482	MAPK1	T220	T221P	221	Missense	proximal	1	no	8.078	16.577	EPSD	GDSC	8.102	Gain
CMGC_MAPK_ERK1_MAPK1_ST	P23396	RPS3	P28482	MAPK1	T220	D215V	215	Missense	distal	-5	no	8.078	8.104	EPSD	GDSC;CCLE	8.102	Gain
CMGC_MAPK_ERK1_MAPK1_ST	P23396	RPS3	P28482	MAPK1	T221	T221P	221	Missense	central	0	yes	16.982	0.000	EPSD	GDSC	8.102	Loss
CMGC_MAPK_ERK1_MAPK1_ST	P23396	RPS3	P28482	MAPK1	T221	D215V	215	Missense	distal	-6	no	16.982	16.873	EPSD	GDSC;CCLE	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P23396	RPS3	P28482	MAPK1	S224	T221P	221	Missense	distal	-3	no	9.076	9.285	EPSD	GDSC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P23396	RPS3	P28482	MAPK1	T242	M236V	236	Missense	distal	-6	no	8.846	8.843	EPSD	GDSC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P23396	RPS3	P28482	MAPK1	T242	P241R	241	Missense	proximal	-1	no	8.846	8.826	EPSD	GDSC;CCLE	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P23396	RPS3	P28482	MAPK1	T242	V240F	240	Missense	proximal	-2	no	8.846	8.078	EPSD	GDSC;CCLE	8.102	Loss
CMGC_MAPK_ERK1_MAPK1_ST	Q5JQC9	AKAP4	P28482	MAPK1	S254	S250P	250	Missense	distal	-4	no	14.098	14.182	EPSD	GDSC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q8IZP0	ABI1	P28482	MAPK1	T196	R194Q	194	Missense	proximal	-2	no	14.788	13.613	EPSD	GDSC;CCLE	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q8IZP0	ABI1	P28482	MAPK1	T336	G331A	331	Missense	distal	-5	no	15.442	15.499	EPSD	GDSC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P35658	NUP214	P28482	MAPK1	T434	T439P	439	Missense	distal	5	no	12.901	12.957	EPSD	GDSC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P35658	NUP214	P28482	MAPK1	T437	T439P	439	Missense	proximal	2	no	14.442	14.493	EPSD	GDSC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P35658	NUP214	P28482	MAPK1	S625	G622E	622	Missense	distal	-3	no	9.113	9.122	EPSD	GDSC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P35658	NUP214	P28482	MAPK1	T628	G622E	622	Missense	distal	-6	no	13.864	13.918	EPSD	GDSC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P35658	NUP214	P28482	MAPK1	S666	A673V	673	Missense	distal	7	no	15.014	15.116	EPSD	GDSC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P35658	NUP214	P28482	MAPK1	T670	A673V	673	Missense	distal	3	no	13.828	13.807	EPSD	GDSC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P35658	NUP214	P28482	MAPK1	S678	A673V	673	Missense	distal	-5	no	16.723	16.694	EPSD	GDSC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P35658	NUP214	P28482	MAPK1	S1081	A1088V	1088	Missense	distal	7	no	12.235	12.336	EPSD	GDSC;CCLE	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P35658	NUP214	P28482	MAPK1	T1243	Q1240*	1240	Missense	distal	-3	no	13.230	12.491	EPSD	GDSC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P35658	NUP214	P28482	MAPK1	S1809	G1807R	1807	Missense	proximal	-2	no	12.938	14.313	PhosphoSitePlus;EPSD	GDSC;CCLE	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P35658	NUP214	P28482	MAPK1	S1963	F1970L	1970	Missense	distal	7	no	14.348	14.289	EPSD	GDSC;CCLE	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P35658	NUP214	P28482	MAPK1	T1981	P1986L	1986	Missense	distal	5	no	9.108	8.895	EPSD	GDSC;CCLE	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P35658	NUP214	P28482	MAPK1	S1985	P1986L	1986	Missense	proximal	1	no	12.287	3.477	EPSD	GDSC;CCLE	8.102	Loss
CMGC_MAPK_ERK1_MAPK1_ST	P35658	NUP214	P28482	MAPK1	S2002	S2006L	2006	Missense	distal	4	no	13.857	13.747	EPSD	GDSC;CCLE	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q15672	TWIST1	P28482	MAPK1	S99	E104Q	104	Missense	distal	5	no	12.934	12.840	EPSD	GDSC;CCLE	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q15672	TWIST1	P28482	MAPK1	S102	E104Q	104	Missense	proximal	2	no	9.723	9.613	EPSD	GDSC;CCLE	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q15796	SMAD2	P28482	MAPK1	S458	S464*	464	Missense	distal	6	no	12.677	11.914	EPSD	GDSC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P01100	FOS	P28482	MAPK1	T232	P233A	233	Missense	proximal	1	no	16.008	8.377	PhosphoSitePlus	GDSC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P01100	FOS	P28482	MAPK1	T325	P326L	326	Missense	proximal	1	no	13.838	5.029	EPSD	GDSC;CCLE	8.102	Loss
CMGC_MAPK_ERK1_MAPK1_ST	P01100	FOS	P28482	MAPK1	T325	C330Y	330	Missense	distal	5	no	13.838	13.950	EPSD	GDSC;CCLE	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P01100	FOS	P28482	MAPK1	T331	P326L	326	Missense	distal	-5	no	15.184	15.333	EPSD	GDSC;CCLE	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P01100	FOS	P28482	MAPK1	T331	C330Y	330	Missense	proximal	-1	no	15.184	15.231	EPSD	GDSC;CCLE	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P01100	FOS	P28482	MAPK1	S362	R359C	359	Missense	distal	-3	no	10.992	10.309	EPSD	GDSC;CCLE	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P01100	FOS	P28482	MAPK1	S362	R359H	359	Missense	distal	-3	no	10.992	10.663	EPSD	GDSC;CCLE	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q14674	ESPL1	P28482	MAPK1	S244	A248V	248	Missense	distal	4	no	15.686	15.680	EPSD	GDSC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q14674	ESPL1	P28482	MAPK1	S244	S238N	238	Missense	distal	-6	no	15.686	15.689	EPSD	GDSC;CCLE	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q14674	ESPL1	P28482	MAPK1	S244	L242R	242	Missense	proximal	-2	no	15.686	15.784	EPSD	GDSC;CCLE	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q14674	ESPL1	P28482	MAPK1	S330	A328V	328	Missense	proximal	-2	no	13.223	14.497	EPSD	GDSC;CCLE	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q14674	ESPL1	P28482	MAPK1	S1126	T1123I	1123	Missense	distal	-3	no	14.009	13.777	PhosphoSitePlus	GDSC;CCLE	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q14674	ESPL1	P28482	MAPK1	S1325	R1320C	1320	Missense	distal	-5	no	8.033	8.263	EPSD	GDSC	8.102	Gain
CMGC_MAPK_ERK1_MAPK1_ST	Q14674	ESPL1	P28482	MAPK1	S1406	S1406L	1406	Missense	central	0	yes	8.549	0.000	EPSD	GDSC;CCLE	8.102	Loss
CMGC_MAPK_ERK1_MAPK1_ST	Q14674	ESPL1	P28482	MAPK1	S1444	V1440I	1440	Missense	distal	-4	no	8.363	8.046	EPSD	GDSC;CCLE	8.102	Loss
CMGC_MAPK_ERK1_MAPK1_ST	Q14674	ESPL1	P28482	MAPK1	T1519	A1514S	1514	Missense	distal	-5	no	13.316	13.265	EPSD	GDSC;CCLE	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q14674	ESPL1	P28482	MAPK1	T1519	S1513L	1513	Missense	distal	-6	no	13.316	13.250	EPSD	GDSC;CCLE	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q14674	ESPL1	P28482	MAPK1	T1519	P1522T	1522	Missense	distal	3	no	13.316	13.377	EPSD	GDSC;CCLE	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q14674	ESPL1	P28482	MAPK1	S1678	R1680G	1680	Missense	proximal	2	no	9.465	9.370	EPSD	GDSC;CCLE	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P19878	NCF2	P28482	MAPK1	T233	P227L	227	Missense	distal	-6	no	16.494	16.402	PhosphoSitePlus	GDSC;CCLE	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P19878	NCF2	P28482	MAPK1	S332	G327A	327	Missense	distal	-5	no	14.060	14.117	EPSD	GDSC;CCLE	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P19878	NCF2	P28482	MAPK1	S332	A325T	325	Missense	distal	-7	no	14.060	14.046	EPSD	GDSC;CCLE	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P19878	NCF2	P28482	MAPK1	S406	E401K	401	Missense	distal	-5	no	9.989	9.967	EPSD	GDSC;CCLE	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q15648	MED1	P28482	MAPK1	T212	H205Y	205	Missense	distal	-7	no	13.734	13.715	EPSD	GDSC;CCLE	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q15648	MED1	P28482	MAPK1	T212	Y210C	210	Missense	proximal	-2	no	13.734	12.085	EPSD	GDSC;CCLE	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q15648	MED1	P28482	MAPK1	T562	G559S	559	Missense	distal	-3	no	13.604	13.616	EPSD	GDSC;CCLE	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q15648	MED1	P28482	MAPK1	T562	F567L	567	Missense	distal	5	no	13.604	13.570	EPSD	GDSC;CCLE	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q15648	MED1	P28482	MAPK1	S675	G674S	674	Missense	proximal	-1	no	13.798	13.809	EPSD	GDSC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q15648	MED1	P28482	MAPK1	S675	M678I	678	Missense	distal	3	no	13.798	13.841	EPSD	GDSC;CCLE	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q15648	MED1	P28482	MAPK1	S675	I680M	680	Missense	distal	5	no	13.798	13.911	EPSD	GDSC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q15648	MED1	P28482	MAPK1	S848	A845T	845	Missense	distal	-3	no	13.014	13.171	EPSD	GDSC;CCLE	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q15648	MED1	P28482	MAPK1	S848	S851G	851	Missense	distal	3	no	13.014	13.028	EPSD	GDSC;CCLE	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q15648	MED1	P28482	MAPK1	S853	N856D	856	Missense	distal	3	no	12.481	12.577	EPSD	GDSC;CCLE	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q15648	MED1	P28482	MAPK1	S853	S851G	851	Missense	proximal	-2	no	12.481	12.121	EPSD	GDSC;CCLE	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q15648	MED1	P28482	MAPK1	S1207	G1201V	1201	Missense	distal	-6	no	13.792	13.748	EPSD	GDSC;CCLE	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q15648	MED1	P28482	MAPK1	S1223	I1225F	1225	Missense	proximal	2	no	13.462	13.474	EPSD	GDSC;CCLE	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q15648	MED1	P28482	MAPK1	S1374	S1375F	1375	Missense	proximal	1	no	6.745	9.571	EPSD	GDSC;CCLE	8.102	Gain
CMGC_MAPK_ERK1_MAPK1_ST	Q15648	MED1	P28482	MAPK1	S1401	S1403T	1403	Missense	proximal	2	no	14.046	14.023	EPSD	GDSC;CCLE	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q15648	MED1	P28482	MAPK1	S1536	D1541E	1541	Missense	distal	5	no	15.287	15.218	EPSD	GDSC;CCLE	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P19525	EIF2AK2	P28482	MAPK1	S83	T90A	90	Missense	distal	7	no	14.665	14.694	EPSD	GDSC;CCLE	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	O94811	TPPP	P28482	MAPK1	S45	G39S	39	Missense	distal	-6	no	13.039	13.056	EPSD	GDSC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	O94811	TPPP	P28482	MAPK1	S160	R165S	165	Missense	distal	5	no	12.599	12.568	PhosphoSitePlus;EPSD	GDSC;CCLE	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	O75582	RPS6KA5	P28482	MAPK1	S253	E260G	260	Missense	distal	7	no	12.735	12.863	EPSD	GDSC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	O75582	RPS6KA5	P28482	MAPK1	S253	D258H	258	Missense	distal	5	no	12.735	12.565	EPSD	GDSC;CCLE	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	O75582	RPS6KA5	P28482	MAPK1	T581	K580R	580	Missense	proximal	-1	no	16.095	16.062	EPSD;PhosphoSitePlus	GDSC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	O75582	RPS6KA5	P28482	MAPK1	S757	T755P	755	Missense	proximal	-2	no	5.883	8.582	EPSD	GDSC;CCLE	8.102	Gain
CMGC_MAPK_ERK1_MAPK1_ST	O75582	RPS6KA5	P28482	MAPK1	T793	S788R	788	Missense	distal	-5	no	9.441	9.414	EPSD	GDSC;CCLE	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P29590	PML	P28482	MAPK1	S527	P526T	526	Missense	proximal	-1	no	15.991	15.949	EPSD;PhosphoSitePlus	GDSC;CCLE	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P29590	PML	P28482	MAPK1	S527	V532I	532	Missense	distal	5	no	15.991	15.817	EPSD;PhosphoSitePlus	GDSC;CCLE	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P29590	PML	P28482	MAPK1	S530	P526T	526	Missense	distal	-4	no	16.722	16.408	EPSD;PhosphoSitePlus	GDSC;CCLE	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P29590	PML	P28482	MAPK1	S530	V532I	532	Missense	proximal	2	no	16.722	16.605	EPSD;PhosphoSitePlus	GDSC;CCLE	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P29590	PML	P28482	MAPK1	T867	R861Q	861	Missense	distal	-6	no	17.434	17.410	EPSD	GDSC;CCLE	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P29590	PML	P28482	MAPK1	T867	L869R	869	Missense	proximal	2	no	17.434	17.695	EPSD	GDSC;CCLE	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q9NRA0	SPHK2	P28482	MAPK1	T503	S496F	496	Missense	distal	-7	no	13.576	13.556	EPSD	GDSC;CCLE	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q9NRA0	SPHK2	P28482	MAPK1	T641	P637T	637	Missense	distal	-4	no	8.489	8.175	EPSD	GDSC;CCLE	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P35236	PTPN7	P28482	MAPK1	T66	T66A	66	Missense	central	0	yes	14.843	0.000	PhosphoSitePlus;EPSD	GDSC	8.102	Loss
CMGC_MAPK_ERK1_MAPK1_ST	P05412	JUN	P28482	MAPK1	S21	S23N	23	Missense	proximal	2	no	8.115	8.067	EPSD	GDSC;CCLE	8.102	Loss
CMGC_MAPK_ERK1_MAPK1_ST	P05412	JUN	P28482	MAPK1	S21	S17W	17	Missense	distal	-4	no	8.115	7.167	EPSD	GDSC;CCLE	8.102	Loss
CMGC_MAPK_ERK1_MAPK1_ST	P05412	JUN	P28482	MAPK1	T91	H87R	87	Missense	distal	-4	no	13.961	14.113	EPSD	GDSC;CCLE	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P05412	JUN	P28482	MAPK1	T93	H87R	87	Missense	distal	-6	no	11.641	11.724	EPSD	GDSC;CCLE	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P05412	JUN	P28482	MAPK1	T239	E234D	234	Missense	distal	-5	no	14.415	14.460	EPSD	GDSC;CCLE	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P32004	L1CAM	P28482	MAPK1	T709	A712T	712	Missense	distal	3	no	14.926	14.910	EPSD	GDSC;CCLE	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q16665	HIF1A	P28482	MAPK1	S65	S58F	58	Missense	distal	-7	no	9.504	9.484	EPSD	GDSC;CCLE	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q16665	HIF1A	P28482	MAPK1	T458	R463*	463	Missense	distal	5	no	12.817	12.503	EPSD	GDSC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q16665	HIF1A	P28482	MAPK1	T458	S465T	465	Missense	distal	7	no	12.817	12.969	EPSD	GDSC;CCLE	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q16665	HIF1A	P28482	MAPK1	S510	Q508*	508	Missense	proximal	-2	no	13.315	3.038	EPSD	GDSC	8.102	Loss
CMGC_MAPK_ERK1_MAPK1_ST	Q16665	HIF1A	P28482	MAPK1	S515	Q508*	508	Missense	distal	-7	no	16.373	16.339	EPSD	GDSC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q16665	HIF1A	P28482	MAPK1	S589	A593P	593	Missense	distal	4	no	11.863	11.967	EPSD	GDSC;CCLE	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q16665	HIF1A	P28482	MAPK1	S657	Y659N	659	Missense	proximal	2	no	13.226	13.346	EPSD	GDSC;CCLE	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q16665	HIF1A	P28482	MAPK1	S668	K674N	674	Missense	distal	6	no	13.191	13.038	EPSD	GDSC;CCLE	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q16665	HIF1A	P28482	MAPK1	S687	P685S	685	Missense	proximal	-2	no	16.981	14.147	EPSD	GDSC;CCLE	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q08499	PDE4D	P28482	MAPK1	S14	R11S	11	Missense	distal	-3	no	8.133	7.977	EPSD	GDSC	8.102	Loss
CMGC_MAPK_ERK1_MAPK1_ST	Q08499	PDE4D	P28482	MAPK1	S18	R11S	11	Missense	distal	-7	no	9.011	9.012	EPSD	GDSC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q08499	PDE4D	P28482	MAPK1	S164	D167Y	167	Missense	distal	3	no	13.051	13.092	EPSD	GDSC;CCLE	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q08499	PDE4D	P28482	MAPK1	S171	D167Y	167	Missense	distal	-4	no	13.993	13.335	EPSD	GDSC;CCLE	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q08499	PDE4D	P28482	MAPK1	S202	D200E	200	Missense	proximal	-2	no	12.862	13.784	EPSD	GDSC;CCLE	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q08499	PDE4D	P28482	MAPK1	T224	V223A	223	Missense	proximal	-1	no	16.153	16.142	EPSD	GDSC;CCLE	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q08499	PDE4D	P28482	MAPK1	S255	Q260*	260	Missense	distal	5	no	14.149	14.005	EPSD	GDSC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q08499	PDE4D	P28482	MAPK1	S348	I346M	346	Missense	proximal	-2	no	14.264	12.144	EPSD	GDSC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q08499	PDE4D	P28482	MAPK1	S715	Q714L	714	Missense	proximal	-1	no	17.970	17.951	EPSD	GDSC;CCLE	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q08499	PDE4D	P28482	MAPK1	S717	Q714L	714	Missense	distal	-3	no	12.429	12.342	EPSD	GDSC;CCLE	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q3V6T2	CCDC88A	P28482	MAPK1	S1837	A1841V	1841	Missense	distal	4	no	14.657	14.651	EPSD	GDSC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q9ULV5	HSF4	P28482	MAPK1	S40	D34E	34	Missense	distal	-6	no	15.426	15.414	EPSD	GDSC;CCLE	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q9ULV5	HSF4	P28482	MAPK1	S298	D302G	302	Missense	distal	4	no	16.871	16.919	PhosphoSitePlus	GDSC;CCLE	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q9ULV5	HSF4	P28482	MAPK1	S340	G337W	337	Missense	distal	-3	no	12.390	11.861	EPSD	GDSC;CCLE	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q8N122	RPTOR	P28482	MAPK1	S696	L694F	694	Missense	proximal	-2	no	14.063	13.339	PhosphoSitePlus;EPSD	GDSC;CCLE	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q8N122	RPTOR	P28482	MAPK1	T699	L694F	694	Missense	distal	-5	no	8.654	8.668	EPSD	GDSC;CCLE	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q8N122	RPTOR	P28482	MAPK1	S711	R716I	716	Missense	distal	5	no	15.912	15.564	EPSD	GDSC;CCLE	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q8N122	RPTOR	P28482	MAPK1	S711	R718H	718	Missense	distal	7	no	15.912	16.131	EPSD	GDSC;CCLE	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q8N122	RPTOR	P28482	MAPK1	T714	R716I	716	Missense	proximal	2	no	16.181	15.897	EPSD	GDSC;CCLE	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q8N122	RPTOR	P28482	MAPK1	T714	R718H	718	Missense	distal	4	no	16.181	16.039	EPSD	GDSC;CCLE	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q8N122	RPTOR	P28482	MAPK1	S722	R716I	716	Missense	distal	-6	no	8.137	8.001	EPSD	GDSC;CCLE	8.102	Loss
CMGC_MAPK_ERK1_MAPK1_ST	Q8N122	RPTOR	P28482	MAPK1	S722	R718H	718	Missense	distal	-4	no	8.137	7.985	EPSD	GDSC;CCLE	8.102	Loss
CMGC_MAPK_ERK1_MAPK1_ST	Q8N122	RPTOR	P28482	MAPK1	S877	S881P	881	Missense	distal	4	no	14.703	14.714	EPSD	GDSC;CCLE	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q8N122	RPTOR	P28482	MAPK1	S881	S881P	881	Missense	central	0	yes	8.691	0.000	EPSD	GDSC;CCLE	8.102	Loss
CMGC_MAPK_ERK1_MAPK1_ST	Q8N122	RPTOR	P28482	MAPK1	T917	Y916H	916	Missense	proximal	-1	no	11.419	11.452	EPSD	GDSC;CCLE	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q8N122	RPTOR	P28482	MAPK1	S920	Y916H	916	Missense	distal	-4	no	8.381	8.812	EPSD	GDSC;CCLE	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P49407	ARRB1	P28482	MAPK1	T275	T275I	275	Missense	central	0	yes	11.183	0.000	EPSD	GDSC	8.102	Loss
CMGC_MAPK_ERK1_MAPK1_ST	P49407	ARRB1	P28482	MAPK1	T275	N280D	280	Missense	distal	5	no	11.183	11.281	EPSD	GDSC;CCLE	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P31645	SLC6A4	P28482	MAPK1	S52	N45S	45	Missense	distal	-7	no	16.017	16.014	EPSD	GDSC;CCLE	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P31645	SLC6A4	P28482	MAPK1	S52	S48L	48	Missense	distal	-4	no	16.017	15.796	EPSD	GDSC;CCLE	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P33076	CIITA	P28482	MAPK1	S288	P292S	292	Missense	distal	4	no	12.958	12.947	EPSD;PhosphoSitePlus	GDSC;CCLE	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P33076	CIITA	P28482	MAPK1	S288	P292A	292	Missense	distal	4	no	12.958	12.854	EPSD;PhosphoSitePlus	GDSC;CCLE	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P78347	GTF2I	P28482	MAPK1	T413	E420V	420	Missense	distal	7	no	10.176	10.518	EPSD	GDSC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P78347	GTF2I	P28482	MAPK1	T558	Q553E	553	Missense	distal	-5	no	12.836	12.736	EPSD	GDSC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q14790	CASP8	P28482	MAPK1	T373	S375P	375	Missense	proximal	2	no	8.624	8.652	EPSD	GDSC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P28482	MAPK1	P28482	MAPK1	T185	T185A	185	Missense	central	0	yes	8.330	0.000	EPSD	GDSC;CCLE	8.102	Loss
CMGC_MAPK_ERK1_MAPK1_ST	P37231	PPARG	P28482	MAPK1	S112	S112C	112	Missense	central	0	yes	18.041	0.000	PhosphoSitePlus	GDSC;CCLE	8.102	Loss
CMGC_MAPK_ERK1_MAPK1_ST	O43521	BCL2L11	P28482	MAPK1	S59	G62V	62	Missense	distal	3	no	13.276	13.249	EPSD	GDSC;CCLE	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	O43521	BCL2L11	P28482	MAPK1	S98	G95E	95	Missense	distal	-3	no	8.256	8.265	EPSD	GDSC;CCLE	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	O43521	BCL2L11	P28482	MAPK1	S104	A106P	106	Missense	proximal	2	no	12.277	12.407	EPSD	GDSC;CCLE	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P35398	RORA	P28482	MAPK1	S49	S54N	54	Missense	distal	5	no	10.233	10.160	EPSD	GDSC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P42229	STAT5A	P28482	MAPK1	S726	Q732H	732	Missense	distal	6	no	12.425	12.407	EPSD	GDSC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P42229	STAT5A	P28482	MAPK1	S726	P731L	731	Missense	distal	5	no	12.425	12.212	EPSD	GDSC;CCLE	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P42229	STAT5A	P28482	MAPK1	S788	A789T	789	Missense	proximal	1	no	9.207	8.339	EPSD	GDSC;CCLE	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q15366	PCBP2	P28482	MAPK1	S208	A207V	207	Missense	proximal	-1	no	9.677	9.688	EPSD	GDSC;CCLE	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q15366	PCBP2	P28482	MAPK1	T213	A207V	207	Missense	distal	-6	no	12.889	12.842	EPSD;PhosphoSitePlus	GDSC;CCLE	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q8N9N5	BANP	P28482	MAPK1	S19	P23S	23	Missense	distal	4	no	16.260	16.249	EPSD	GDSC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q8N9N5	BANP	P28482	MAPK1	T337	F333V	333	Missense	distal	-4	no	15.315	15.305	PhosphoSitePlus;EPSD	GDSC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	O00429	DNM1L	P28482	MAPK1	S136	P137T	137	Missense	proximal	1	no	15.773	7.274	EPSD	GDSC	8.102	Loss
CMGC_MAPK_ERK1_MAPK1_ST	O00429	DNM1L	P28482	MAPK1	S136	V139I	139	Missense	distal	3	no	15.773	15.843	EPSD	GDSC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	O00429	DNM1L	P28482	MAPK1	S526	E523*	523	Missense	distal	-3	no	8.336	7.480	EPSD	GDSC	8.102	Loss
CMGC_MAPK_ERK1_MAPK1_ST	O00429	DNM1L	P28482	MAPK1	S548	A551T	551	Missense	distal	3	no	14.142	14.126	EPSD	GDSC;CCLE	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	O00429	DNM1L	P28482	MAPK1	S548	P547L	547	Missense	proximal	-1	no	14.142	14.083	EPSD	GDSC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	O00429	DNM1L	P28482	MAPK1	S548	A550D	550	Missense	proximal	2	no	14.142	14.256	EPSD	GDSC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q5T447	HECTD3	P28482	MAPK1	S389	R392*	392	Missense	distal	3	no	8.200	8.306	EPSD	GDSC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P00533	EGFR	P28482	MAPK1	S227	N234D	234	Missense	distal	7	no	13.009	13.023	EPSD	GDSC;CCLE	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P00533	EGFR	P28482	MAPK1	S752	A750E	750	Missense	proximal	-2	no	15.051	15.818	EPSD	GDSC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P00533	EGFR	P28482	MAPK1	T1085	T1085N	1085	Missense	central	0	yes	8.248	0.000	EPSD	GDSC;CCLE	8.102	Loss
CMGC_MAPK_ERK1_MAPK1_ST	P00533	EGFR	P28482	MAPK1	S1153	W1157C	1157	Missense	distal	4	no	14.713	14.738	EPSD	GDSC;CCLE	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q8IW41	MAPKAPK5	P28482	MAPK1	S212	P213Q	213	Missense	proximal	1	no	14.838	6.344	EPSD	GDSC;CCLE	8.102	Loss
CMGC_MAPK_ERK1_MAPK1_ST	Q8IW41	MAPKAPK5	P28482	MAPK1	S212	P215S	215	Missense	distal	3	no	14.838	14.907	EPSD	GDSC;CCLE	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q8IW41	MAPKAPK5	P28482	MAPK1	T214	P213Q	213	Missense	proximal	-1	no	14.150	14.109	EPSD	GDSC;CCLE	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q8IW41	MAPKAPK5	P28482	MAPK1	T214	P215S	215	Missense	proximal	1	no	14.150	4.755	EPSD	GDSC;CCLE	8.102	Loss
CMGC_MAPK_ERK1_MAPK1_ST	Q8IW41	MAPKAPK5	P28482	MAPK1	T217	P213Q	213	Missense	distal	-4	no	11.667	11.474	EPSD	GDSC;CCLE	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q8IW41	MAPKAPK5	P28482	MAPK1	T217	P215S	215	Missense	proximal	-2	no	11.667	8.832	EPSD	GDSC;CCLE	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P07196	NEFL	P28482	MAPK1	S48	R55C	55	Missense	distal	7	no	8.626	9.282	EPSD	GDSC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P07196	NEFL	P28482	MAPK1	S435	T436P	436	Missense	proximal	1	no	5.100	13.598	EPSD	GDSC	8.102	Gain
CMGC_MAPK_ERK1_MAPK1_ST	O43524	FOXO3	P28482	MAPK1	S280	Q275*	275	Missense	distal	-5	no	9.635	9.791	EPSD	GDSC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	O43524	FOXO3	P28482	MAPK1	S325	V320I	320	Missense	distal	-5	no	14.621	14.734	EPSD	GDSC;CCLE	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	O43524	FOXO3	P28482	MAPK1	S402	M408V	408	Missense	distal	6	no	13.773	13.992	EPSD	GDSC;CCLE	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	O43524	FOXO3	P28482	MAPK1	S574	V576A	576	Missense	proximal	2	no	13.629	13.553	EPSD	GDSC;CCLE	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P24941	CDK2	P28482	MAPK1	T221	D223G	223	Missense	proximal	2	no	15.635	15.669	EPSD	GDSC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q05209	PTPN12	P28482	MAPK1	S19	N23T	23	Missense	distal	4	no	15.780	15.704	EPSD	GDSC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q05209	PTPN12	P28482	MAPK1	T81	R74*	74	Missense	distal	-7	no	13.888	13.863	EPSD	GDSC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q05209	PTPN12	P28482	MAPK1	T81	T78P	78	Missense	distal	-3	no	13.888	14.098	EPSD	GDSC;CCLE	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q05209	PTPN12	P28482	MAPK1	T340	E346K	346	Missense	distal	6	no	8.833	8.856	EPSD	GDSC;CCLE	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q05209	PTPN12	P28482	MAPK1	T340	C343F	343	Missense	distal	3	no	8.833	8.792	EPSD	GDSC;CCLE	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q05209	PTPN12	P28482	MAPK1	S468	S466Y	466	Missense	proximal	-2	no	14.904	15.621	EPSD	GDSC;CCLE	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q05209	PTPN12	P28482	MAPK1	T578	H584Y	584	Missense	distal	6	no	13.878	13.565	EPSD	GDSC;CCLE	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q05209	PTPN12	P28482	MAPK1	S588	H584Y	584	Missense	distal	-4	no	14.283	13.851	EPSD	GDSC;CCLE	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q05209	PTPN12	P28482	MAPK1	S684	E690K	690	Missense	distal	6	no	10.959	10.983	EPSD	GDSC;CCLE	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q05209	PTPN12	P28482	MAPK1	T693	E690K	690	Missense	distal	-3	no	12.171	12.093	EPSD	GDSC;CCLE	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q96Q27	ASB2	P28482	MAPK1	S28	A24S	24	Missense	distal	-4	no	9.722	9.931	EPSD	GDSC;CCLE	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q96Q27	ASB2	P28482	MAPK1	S29	A24S	24	Missense	distal	-5	no	14.784	14.733	EPSD	GDSC;CCLE	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q07820	MCL1	P28482	MAPK1	S121	M120V	120	Missense	proximal	-1	no	14.752	14.776	EPSD	GDSC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q9UKX7	NUP50	P28482	MAPK1	S296	P297L	297	Missense	proximal	1	no	13.409	4.599	EPSD	GDSC;CCLE	8.102	Loss
CMGC_MAPK_ERK1_MAPK1_ST	Q08493	PDE4C	P28482	MAPK1	S114	R117H	117	Missense	distal	3	no	8.476	8.519	EPSD	GDSC;CCLE	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q96LC9	BMF	P28482	MAPK1	S74	Q80K	80	Missense	distal	6	no	15.634	15.978	PhosphoSitePlus;EPSD	GDSC;CCLE	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q96LC9	BMF	P28482	MAPK1	S77	Q80K	80	Missense	distal	3	no	18.767	18.696	EPSD;PhosphoSitePlus	GDSC;CCLE	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q96LC9	BMF	P28482	MAPK1	S109	A108V	108	Missense	proximal	-1	no	9.393	9.404	EPSD	GDSC;CCLE	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q15746	MYLK	P28482	MAPK1	S16	S13Y	13	Missense	distal	-3	no	8.118	7.848	EPSD	GDSC;CCLE	8.102	Loss
CMGC_MAPK_ERK1_MAPK1_ST	Q15746	MYLK	P28482	MAPK1	T335	P336L	336	Missense	proximal	1	no	14.658	5.848	EPSD	GDSC	8.102	Loss
CMGC_MAPK_ERK1_MAPK1_ST	Q15746	MYLK	P28482	MAPK1	S515	A513V	513	Missense	proximal	-2	no	9.945	11.219	EPSD	GDSC;CCLE	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q15746	MYLK	P28482	MAPK1	S947	R954H	954	Missense	distal	7	no	14.753	14.972	EPSD	GDSC;CCLE	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q15746	MYLK	P28482	MAPK1	T978	P973L	973	Missense	distal	-5	no	16.073	16.222	EPSD	GDSC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q15746	MYLK	P28482	MAPK1	S1776	G1775E	1775	Missense	proximal	-1	no	12.880	12.919	EPSD	GDSC;CCLE	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q15746	MYLK	P28482	MAPK1	S1776	S1776P	1776	Missense	central	0	yes	12.880	0.000	EPSD	GDSC;CCLE	8.102	Loss
CMGC_MAPK_ERK1_MAPK1_ST	Q15746	MYLK	P28482	MAPK1	S1779	G1775E	1775	Missense	distal	-4	no	16.167	16.488	PhosphoSitePlus	GDSC;CCLE	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q15746	MYLK	P28482	MAPK1	S1779	L1786I	1786	Missense	distal	7	no	16.167	16.427	PhosphoSitePlus	GDSC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q15746	MYLK	P28482	MAPK1	S1779	S1776P	1776	Missense	distal	-3	no	16.167	16.343	PhosphoSitePlus	GDSC;CCLE	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	O75581	LRP6	P28482	MAPK1	S646	R644*	644	Missense	proximal	-2	no	8.517	-2.935	EPSD	GDSC	8.102	Loss
CMGC_MAPK_ERK1_MAPK1_ST	O75581	LRP6	P28482	MAPK1	T1479	T1479I	1479	Missense	central	0	yes	9.033	0.000	EPSD	GDSC	8.102	Loss
CMGC_MAPK_ERK1_MAPK1_ST	O75581	LRP6	P28482	MAPK1	S1490	R1495Q	1495	Missense	distal	5	no	17.067	16.897	PhosphoSitePlus;EPSD	GDSC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	O75581	LRP6	P28482	MAPK1	T1493	R1495Q	1495	Missense	proximal	2	no	8.374	8.083	EPSD	GDSC	8.102	Loss
CMGC_MAPK_ERK1_MAPK1_ST	O75581	LRP6	P28482	MAPK1	S1607	S1612F	1612	Missense	distal	5	no	18.829	18.631	EPSD	GDSC;CCLE	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q02447	SP3	P28482	MAPK1	T115	D121E	121	Missense	distal	6	no	11.451	11.530	EPSD	GDSC;CCLE	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q02447	SP3	P28482	MAPK1	S375	S375L	375	Missense	central	0	yes	14.636	0.000	EPSD	GDSC;CCLE	8.102	Loss
CMGC_MAPK_ERK1_MAPK1_ST	Q02447	SP3	P28482	MAPK1	S375	L368F	368	Missense	distal	-7	no	14.636	14.623	EPSD	GDSC;CCLE	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q02447	SP3	P28482	MAPK1	S378	S375L	375	Missense	distal	-3	no	8.642	8.435	EPSD	GDSC;CCLE	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q8IX03	WWC1	P28482	MAPK1	S358	E353Q	353	Missense	distal	-5	no	15.100	15.200	EPSD	GDSC;CCLE	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q8IX03	WWC1	P28482	MAPK1	S899	K906E	906	Missense	distal	7	no	14.356	14.349	EPSD	GDSC;CCLE	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q8IX03	WWC1	P28482	MAPK1	T912	K906E	906	Missense	distal	-6	no	12.850	12.876	EPSD	GDSC;CCLE	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q8IX03	WWC1	P28482	MAPK1	T912	L919F	919	Missense	distal	7	no	12.850	12.909	EPSD	GDSC;CCLE	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q8IX03	WWC1	P28482	MAPK1	S936	R941Q	941	Missense	distal	5	no	9.701	9.531	EPSD	GDSC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P11362	FGFR1	P28482	MAPK1	S797	E792K	792	Missense	distal	-5	no	8.407	8.384	EPSD	GDSC;CCLE	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P14784	IL2RB	P28482	MAPK1	S431	G437S	437	Missense	distal	6	no	13.075	13.152	EPSD	GDSC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P14784	IL2RB	P28482	MAPK1	T476	T476I	476	Missense	central	0	yes	15.778	0.000	PhosphoSitePlus	GDSC	8.102	Loss
CMGC_MAPK_ERK1_MAPK1_ST	P14784	IL2RB	P28482	MAPK1	T533	L531V	531	Missense	proximal	-2	no	8.864	8.908	EPSD	GDSC;CCLE	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P14784	IL2RB	P28482	MAPK1	S538	L531V	531	Missense	distal	-7	no	8.211	8.204	EPSD	GDSC;CCLE	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P49841	GSK3B	P28482	MAPK1	T7	T8P	8	Missense	proximal	1	no	8.162	16.661	EPSD	GDSC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P49841	GSK3B	P28482	MAPK1	T324	R319*	319	Missense	distal	-5	no	14.097	14.330	EPSD	GDSC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P06239	LCK	P28482	MAPK1	S42	R45Q	45	Missense	distal	3	no	9.303	9.325	EPSD	GDSC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P06239	LCK	P28482	MAPK1	S42	S42L	42	Missense	central	0	yes	9.303	0.000	EPSD	GDSC	8.102	Loss
CMGC_MAPK_ERK1_MAPK1_ST	P06239	LCK	P28482	MAPK1	S194	G201S	201	Missense	distal	7	no	15.100	15.031	EPSD	GDSC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P06239	LCK	P28482	MAPK1	T198	G201S	201	Missense	distal	3	no	9.968	9.953	EPSD	GDSC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P06239	LCK	P28482	MAPK1	S373	S377R	377	Missense	distal	4	no	8.607	8.584	EPSD	GDSC;CCLE	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P42702	LIFR	P28482	MAPK1	T904	V910F	910	Missense	distal	6	no	15.958	15.732	EPSD	GDSC;CCLE	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P42702	LIFR	P28482	MAPK1	S927	E931K	931	Missense	distal	4	no	14.180	14.194	EPSD	GDSC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P42702	LIFR	P28482	MAPK1	S927	D922G	922	Missense	distal	-5	no	14.180	14.177	EPSD	GDSC;CCLE	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P42702	LIFR	P28482	MAPK1	S927	E921K	921	Missense	distal	-6	no	14.180	14.154	EPSD	GDSC;CCLE	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P42702	LIFR	P28482	MAPK1	S1041	N1035H	1035	Missense	distal	-6	no	15.138	15.086	EPSD	GDSC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P42702	LIFR	P28482	MAPK1	S1056	S1059G	1059	Missense	distal	3	no	10.056	10.071	EPSD	GDSC;CCLE	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P42702	LIFR	P28482	MAPK1	S1059	S1059G	1059	Missense	central	0	yes	13.739	0.000	EPSD	GDSC;CCLE	8.102	Loss
CMGC_MAPK_ERK1_MAPK1_ST	P42702	LIFR	P28482	MAPK1	S1062	S1059G	1059	Missense	distal	-3	no	8.299	8.286	EPSD	GDSC;CCLE	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q14247	CTTN	P28482	MAPK1	S405	Q409K	409	Missense	distal	4	no	15.769	15.854	PhosphoSitePlus;EPSD	GDSC;CCLE	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q00059	TFAM	P28482	MAPK1	S160	R159H	159	Missense	proximal	-1	no	8.338	8.315	EPSD	GDSC;CCLE	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q00059	TFAM	P28482	MAPK1	S160	G153V	153	Missense	distal	-7	no	8.338	8.337	EPSD	GDSC;CCLE	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q05682	CALD1	P28482	MAPK1	S153	R159K	159	Missense	distal	6	no	8.468	8.632	EPSD	GDSC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q05682	CALD1	P28482	MAPK1	S480	D483V	483	Missense	distal	3	no	8.366	8.337	EPSD	GDSC;CCLE	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q05682	CALD1	P28482	MAPK1	S480	K475R	475	Missense	distal	-5	no	8.366	8.411	EPSD	GDSC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q05682	CALD1	P28482	MAPK1	T753	N757S	757	Missense	distal	4	no	11.115	11.153	EPSD	GDSC;CCLE	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q05682	CALD1	P28482	MAPK1	S759	P764L	764	Missense	distal	5	no	12.022	11.808	EPSD	GDSC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q05682	CALD1	P28482	MAPK1	S759	S765T	765	Missense	distal	6	no	12.022	11.811	EPSD	GDSC;CCLE	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q05682	CALD1	P28482	MAPK1	S759	N757S	757	Missense	proximal	-2	no	12.022	12.007	EPSD	GDSC;CCLE	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q05682	CALD1	P28482	MAPK1	S789	T791A	791	Missense	proximal	2	no	16.099	16.020	EPSD	GDSC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P46527	CDKN1B	P28482	MAPK1	S178	G177S	177	Missense	proximal	-1	no	16.020	16.031	EPSD;PhosphoSitePlus	GDSC;CCLE	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P11308	ERG	P28482	MAPK1	S88	D90G	90	Missense	proximal	2	no	15.332	15.366	EPSD	GDSC;CCLE	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P11308	ERG	P28482	MAPK1	S222	P223A	223	Missense	proximal	1	no	13.432	5.802	EPSD;PhosphoSitePlus	GDSC;CCLE	8.102	Loss
CMGC_MAPK_ERK1_MAPK1_ST	P22736	NR4A1	P28482	MAPK1	S23	T27I	27	Missense	distal	4	no	8.780	8.727	EPSD	GDSC;CCLE	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P22736	NR4A1	P28482	MAPK1	S23	D24E	24	Missense	proximal	1	no	8.780	8.705	EPSD	GDSC;CCLE	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P22736	NR4A1	P28482	MAPK1	T27	T27I	27	Missense	central	0	yes	18.074	0.000	EPSD	GDSC;CCLE	8.102	Loss
CMGC_MAPK_ERK1_MAPK1_ST	P22736	NR4A1	P28482	MAPK1	T27	D24E	24	Missense	distal	-3	no	18.074	18.022	EPSD	GDSC;CCLE	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P22736	NR4A1	P28482	MAPK1	S95	P96R	96	Missense	proximal	1	no	12.717	3.063	EPSD	GDSC;CCLE	8.102	Loss
CMGC_MAPK_ERK1_MAPK1_ST	P22736	NR4A1	P28482	MAPK1	S152	L151V	151	Missense	proximal	-1	no	14.120	14.154	EPSD	GDSC;CCLE	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P22736	NR4A1	P28482	MAPK1	S199	S201T	201	Missense	proximal	2	no	14.359	14.336	EPSD	GDSC;CCLE	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P22736	NR4A1	P28482	MAPK1	S205	S201T	201	Missense	distal	-4	no	14.005	13.775	EPSD	GDSC;CCLE	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P27708	CAD	P28482	MAPK1	S1113	A1114V	1114	Missense	proximal	1	no	9.752	7.842	EPSD	GDSC	8.102	Loss
CMGC_MAPK_ERK1_MAPK1_ST	P27708	CAD	P28482	MAPK1	T1884	P1891H	1891	Missense	distal	7	no	11.136	11.370	EPSD	GDSC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P27708	CAD	P28482	MAPK1	T1884	Y1890C	1890	Missense	distal	6	no	11.136	10.887	EPSD	GDSC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P27708	CAD	P28482	MAPK1	S1900	V1895I	1895	Missense	distal	-5	no	11.600	11.713	EPSD	GDSC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q00613	HSF1	P28482	MAPK1	S290	R296H	296	Missense	distal	6	no	8.815	8.617	EPSD	GDSC;CCLE	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q00613	HSF1	P28482	MAPK1	S292	R296H	296	Missense	distal	4	no	14.238	14.096	EPSD	GDSC;CCLE	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q00613	HSF1	P28482	MAPK1	S303	P308L	308	Missense	distal	5	no	17.219	17.006	EPSD	GDSC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q00613	HSF1	P28482	MAPK1	S303	R296H	296	Missense	distal	-7	no	17.219	17.208	EPSD	GDSC;CCLE	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q00613	HSF1	P28482	MAPK1	S307	P308L	308	Missense	proximal	1	no	15.590	6.780	EPSD	GDSC	8.102	Loss
CMGC_MAPK_ERK1_MAPK1_ST	Q00613	HSF1	P28482	MAPK1	S307	E312A	312	Missense	distal	5	no	15.590	15.474	EPSD	GDSC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q00613	HSF1	P28482	MAPK1	S314	P308L	308	Missense	distal	-6	no	14.840	14.748	EPSD	GDSC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q00613	HSF1	P28482	MAPK1	S314	E312A	312	Missense	proximal	-2	no	14.840	14.073	EPSD	GDSC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q00613	HSF1	P28482	MAPK1	S363	R360Q	360	Missense	distal	-3	no	16.964	16.687	EPSD	GDSC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q00613	HSF1	P28482	MAPK1	S363	R360W	360	Missense	distal	-3	no	16.964	16.266	EPSD	GDSC;CCLE	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q00613	HSF1	P28482	MAPK1	S419	S419R	419	Missense	central	0	yes	14.430	0.000	EPSD	GDSC	8.102	Loss
CMGC_MAPK_ERK1_MAPK1_ST	Q00613	HSF1	P28482	MAPK1	S419	S421W	421	Missense	proximal	2	no	14.430	14.203	EPSD	GDSC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q00613	HSF1	P28482	MAPK1	S419	V422L	422	Missense	distal	3	no	14.430	14.462	EPSD	GDSC;CCLE	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q00613	HSF1	P28482	MAPK1	S458	S458I	458	Missense	central	0	yes	15.044	0.000	EPSD	GDSC;CCLE	8.102	Loss
CMGC_MAPK_ERK1_MAPK1_ST	Q9Y6K1	DNMT3A	P28482	MAPK1	T65	G63S	63	Missense	proximal	-2	no	13.845	14.205	EPSD	GDSC;CCLE	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q9Y6K1	DNMT3A	P28482	MAPK1	S75	S73F	73	Missense	proximal	-2	no	11.951	12.144	EPSD	GDSC;CCLE	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q9Y6K1	DNMT3A	P28482	MAPK1	T138	A131P	131	Missense	distal	-7	no	12.941	12.944	EPSD	GDSC;CCLE	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q9Y6K1	DNMT3A	P28482	MAPK1	S243	E241*	241	Missense	proximal	-2	no	13.554	2.663	EPSD	GDSC	8.102	Loss
CMGC_MAPK_ERK1_MAPK1_ST	Q9Y6K1	DNMT3A	P28482	MAPK1	S255	S255F	255	Missense	central	0	yes	17.002	0.000	PhosphoSitePlus	GDSC;CCLE	8.102	Loss
CMGC_MAPK_ERK1_MAPK1_ST	Q9Y6K1	DNMT3A	P28482	MAPK1	T261	S255F	255	Missense	distal	-6	no	13.031	12.947	EPSD	GDSC;CCLE	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q9UBN7	HDAC6	P28482	MAPK1	S412	R418W	418	Missense	distal	6	no	14.167	13.244	EPSD	GDSC;CCLE	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q9UBN7	HDAC6	P28482	MAPK1	T527	R529H	529	Missense	proximal	2	no	12.432	12.189	EPSD	GDSC;CCLE	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q9UBN7	HDAC6	P28482	MAPK1	T1031	P1033S	1033	Missense	proximal	2	no	13.802	13.774	PhosphoSitePlus	GDSC;CCLE	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q9UBN7	HDAC6	P28482	MAPK1	T1034	P1033S	1033	Missense	proximal	-1	no	8.515	8.472	EPSD	GDSC;CCLE	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q9UBN7	HDAC6	P28482	MAPK1	S1035	P1033S	1033	Missense	proximal	-2	no	16.449	13.614	EPSD	GDSC;CCLE	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P33981	TTK	P28482	MAPK1	S80	V77A	77	Missense	distal	-3	no	9.018	8.958	EPSD	GDSC;CCLE	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P33981	TTK	P28482	MAPK1	S281	P275T	275	Missense	distal	-6	no	15.075	15.025	EPSD	GDSC;CCLE	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P33981	TTK	P28482	MAPK1	S436	P438S	438	Missense	proximal	2	no	13.874	13.846	EPSD	GDSC;CCLE	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P33981	TTK	P28482	MAPK1	S440	P438S	438	Missense	proximal	-2	no	9.872	7.038	EPSD	GDSC;CCLE	8.102	Loss
CMGC_MAPK_ERK1_MAPK1_ST	Q86UR1	NOXA1	P28482	MAPK1	S470	A463T	463	Missense	distal	-7	no	11.822	11.807	EPSD	GDSC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q86UR1	NOXA1	P28482	MAPK1	S470	A463P	463	Missense	distal	-7	no	11.822	11.824	EPSD	GDSC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P47712	PLA2G4A	P28482	MAPK1	T41	P44H	44	Missense	distal	3	no	16.542	16.631	EPSD	GDSC;CCLE	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P47712	PLA2G4A	P28482	MAPK1	T156	E163*	163	Missense	distal	7	no	7.910	8.478	EPSD	GDSC	8.102	Gain
CMGC_MAPK_ERK1_MAPK1_ST	P47712	PLA2G4A	P28482	MAPK1	S454	A452V	452	Missense	proximal	-2	no	7.399	8.673	EPSD	GDSC;CCLE	8.102	Gain
CMGC_MAPK_ERK1_MAPK1_ST	P47712	PLA2G4A	P28482	MAPK1	S508	Q513K	513	Missense	distal	5	no	8.279	8.314	EPSD	GDSC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P47712	PLA2G4A	P28482	MAPK1	S515	Q513K	513	Missense	proximal	-2	no	8.506	9.081	EPSD	GDSC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P47712	PLA2G4A	P28482	MAPK1	S515	L521M	521	Missense	distal	6	no	8.506	8.480	EPSD	GDSC;CCLE	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q12931	TRAP1	P28482	MAPK1	T40	R47*	47	Missense	distal	7	no	8.206	8.711	EPSD	GDSC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q92908	GATA6	P28482	MAPK1	T34	F27L	27	Missense	distal	-7	no	15.730	15.742	EPSD	GDSC;CCLE	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q92908	GATA6	P28482	MAPK1	S37	S44F	44	Missense	distal	7	no	17.103	17.451	EPSD	GDSC;CCLE	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q92908	GATA6	P28482	MAPK1	T62	E68V	68	Missense	distal	6	no	9.735	9.486	EPSD	GDSC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q92908	GATA6	P28482	MAPK1	S531	S531F	531	Missense	central	0	yes	13.901	0.000	EPSD	GDSC;CCLE	8.102	Loss
CMGC_MAPK_ERK1_MAPK1_ST	Q92908	GATA6	P28482	MAPK1	T534	S531F	531	Missense	distal	-3	no	9.999	9.766	EPSD	GDSC;CCLE	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P04637	TP53	P28482	MAPK1	S33	Q38*	38	Missense	distal	5	no	13.820	13.676	EPSD	GDSC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P04637	TP53	P28482	MAPK1	T81	A74S	74	Missense	distal	-7	no	14.705	14.703	EPSD	GDSC;CCLE	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P04637	TP53	P28482	MAPK1	S127	Y126*	126	Missense	proximal	-1	no	14.148	14.112	EPSD	GDSC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P04637	TP53	P28482	MAPK1	S127	K120*	120	Missense	distal	-7	no	14.148	14.119	EPSD	GDSC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P04637	TP53	P28482	MAPK1	T150	Q144*	144	Missense	distal	-6	no	11.263	11.143	EPSD	GDSC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P04637	TP53	P28482	MAPK1	T150	W146*	146	Missense	distal	-4	no	11.263	11.587	EPSD	GDSC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P04637	TP53	P28482	MAPK1	S315	Q317*	317	Missense	proximal	2	no	13.607	13.558	EPSD	GDSC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P04637	TP53	P28482	MAPK1	S315	K319*	319	Missense	distal	4	no	13.607	13.318	EPSD	GDSC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P04637	TP53	P28482	MAPK1	S392	G389W	389	Missense	distal	-3	no	8.624	8.095	EPSD	GDSC;CCLE	8.102	Loss
CMGC_MAPK_ERK1_MAPK1_ST	Q14686	NCOA6	P28482	MAPK1	T416	V414F	414	Missense	proximal	-2	no	14.203	13.435	EPSD	GDSC;CCLE	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q14686	NCOA6	P28482	MAPK1	T932	G939D	939	Missense	distal	7	no	14.252	14.179	EPSD	GDSC;CCLE	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q14686	NCOA6	P28482	MAPK1	T1103	S1107N	1107	Missense	distal	4	no	13.609	13.572	EPSD	GDSC;CCLE	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q14686	NCOA6	P28482	MAPK1	T1516	E1523K	1523	Missense	distal	7	no	12.348	12.356	EPSD	GDSC;CCLE	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q14686	NCOA6	P28482	MAPK1	S1721	P1722S	1722	Missense	proximal	1	no	12.747	3.352	EPSD	GDSC;CCLE	8.102	Loss
CMGC_MAPK_ERK1_MAPK1_ST	Q14686	NCOA6	P28482	MAPK1	T1878	T1880M	1880	Missense	proximal	2	no	13.582	13.441	EPSD	GDSC;CCLE	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q14686	NCOA6	P28482	MAPK1	T1880	T1880M	1880	Missense	central	0	yes	12.985	0.000	EPSD	GDSC;CCLE	8.102	Loss
CMGC_MAPK_ERK1_MAPK1_ST	Q14686	NCOA6	P28482	MAPK1	S2043	S2038C	2038	Missense	distal	-5	no	10.590	10.793	EPSD	GDSC;CCLE	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q9UQC2	GAB2	P28482	MAPK1	S218	T225I	225	Missense	distal	7	no	8.725	9.121	EPSD	GDSC;CCLE	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q9UQC2	GAB2	P28482	MAPK1	T294	T294I	294	Missense	central	0	yes	9.420	0.000	EPSD	GDSC;CCLE	8.102	Loss
CMGC_MAPK_ERK1_MAPK1_ST	Q9UQC2	GAB2	P28482	MAPK1	T294	T294P	294	Missense	central	0	yes	9.420	0.000	EPSD	GDSC;CCLE	8.102	Loss
CMGC_MAPK_ERK1_MAPK1_ST	P10828	THRB	P28482	MAPK1	S55	S54L	54	Missense	proximal	-1	no	14.655	14.639	EPSD	GDSC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P10828	THRB	P28482	MAPK1	S142	P141L	141	Missense	proximal	-1	no	8.459	8.399	PhosphoSitePlus	GDSC;CCLE	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q9NRF2	SH2B1	P28482	MAPK1	S88	R82Q	82	Missense	distal	-6	no	13.850	13.827	EPSD	GDSC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q9NRF2	SH2B1	P28482	MAPK1	T396	A393P	393	Missense	distal	-3	no	8.361	8.728	EPSD	GDSC;CCLE	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P53355	DAPK1	P28482	MAPK1	S734	P732A	732	Missense	proximal	-2	no	19.425	16.278	PhosphoSitePlus	GDSC;CCLE	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P53355	DAPK1	P28482	MAPK1	S734	T741A	741	Missense	distal	7	no	19.425	19.454	PhosphoSitePlus	GDSC;CCLE	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P41182	BCL6	P28482	MAPK1	S343	N342Y	342	Missense	proximal	-1	no	17.275	17.194	EPSD;PhosphoSitePlus	GDSC;CCLE	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P41182	BCL6	P28482	MAPK1	S404	S404P	404	Missense	central	0	yes	13.330	0.000	EPSD	GDSC;CCLE	8.102	Loss
CMGC_MAPK_ERK1_MAPK1_ST	P41182	BCL6	P28482	MAPK1	S404	Q397H	397	Missense	distal	-7	no	13.330	13.311	EPSD	GDSC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P41182	BCL6	P28482	MAPK1	S404	P405Q	405	Missense	proximal	1	no	13.330	4.836	EPSD	GDSC;CCLE	8.102	Loss
CMGC_MAPK_ERK1_MAPK1_ST	P41182	BCL6	P28482	MAPK1	S427	Q426E	426	Missense	proximal	-1	no	13.658	13.684	EPSD	GDSC;CCLE	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P41182	BCL6	P28482	MAPK1	S457	M454T	454	Missense	distal	-3	no	13.867	14.095	EPSD	GDSC;CCLE	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q13164	MAPK7	P28482	MAPK1	S707	M704V	704	Missense	distal	-3	no	13.239	13.369	EPSD	GDSC;CCLE	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q13164	MAPK7	P28482	MAPK1	S774	A779D	779	Missense	distal	5	no	8.011	8.196	EPSD	GDSC;CCLE	8.102	Gain
CMGC_MAPK_ERK1_MAPK1_ST	Q9H9Z2	LIN28A	P28482	MAPK1	T189	R192*	192	Missense	distal	3	no	12.220	12.327	EPSD	GDSC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q9H9Z2	LIN28A	P28482	MAPK1	T189	R192P	192	Missense	distal	3	no	12.220	12.175	EPSD	GDSC;CCLE	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q9H9Z2	LIN28A	P28482	MAPK1	T189	G186R	186	Missense	distal	-3	no	12.220	12.389	EPSD	GDSC;CCLE	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q9H9Z2	LIN28A	P28482	MAPK1	T189	R192G	192	Missense	distal	3	no	12.220	12.258	EPSD	GDSC;CCLE	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q12772	SREBF2	P28482	MAPK1	S101	T96A	96	Missense	distal	-5	no	13.077	13.099	EPSD	GDSC;CCLE	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P06401	PGR	P28482	MAPK1	S130	A133S	133	Missense	distal	3	no	13.049	13.040	EPSD	GDSC;CCLE	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P06401	PGR	P28482	MAPK1	S130	C134*	134	Missense	distal	4	no	13.049	13.029	EPSD	GDSC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P06401	PGR	P28482	MAPK1	S162	R167Q	167	Missense	distal	5	no	18.703	18.533	EPSD	GDSC;CCLE	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P06401	PGR	P28482	MAPK1	S344	A338P	338	Missense	distal	-6	no	9.114	9.153	EPSD	GDSC;CCLE	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P06401	PGR	P28482	MAPK1	S344	P342L	342	Missense	proximal	-2	no	9.114	7.197	EPSD	GDSC;CCLE	8.102	Loss
CMGC_MAPK_ERK1_MAPK1_ST	P06401	PGR	P28482	MAPK1	S345	A338P	338	Missense	distal	-7	no	15.210	15.213	EPSD	GDSC;CCLE	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P06401	PGR	P28482	MAPK1	S345	P342L	342	Missense	distal	-3	no	15.210	14.827	EPSD	GDSC;CCLE	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P06401	PGR	P28482	MAPK1	S400	E395G	395	Missense	distal	-5	no	13.209	13.251	EPSD	GDSC;CCLE	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P46695	IER3	P28482	MAPK1	T37	G32S	32	Missense	distal	-5	no	9.288	9.294	EPSD	GDSC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q15596	NCOA2	P28482	MAPK1	S402	N401S	401	Missense	proximal	-1	no	13.635	13.586	EPSD	GDSC;CCLE	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q15596	NCOA2	P28482	MAPK1	T457	A464V	464	Missense	distal	7	no	12.271	12.373	EPSD	GDSC;CCLE	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q15596	NCOA2	P28482	MAPK1	S469	A464V	464	Missense	distal	-5	no	12.831	12.802	EPSD	GDSC;CCLE	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q15596	NCOA2	P28482	MAPK1	S487	S487L	487	Missense	central	0	yes	11.426	0.000	EPSD	GDSC;CCLE	8.102	Loss
CMGC_MAPK_ERK1_MAPK1_ST	Q15596	NCOA2	P28482	MAPK1	S487	M485L	485	Missense	proximal	-2	no	11.426	13.523	EPSD	GDSC;CCLE	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q15596	NCOA2	P28482	MAPK1	S493	S487L	487	Missense	distal	-6	no	15.547	15.481	EPSD	GDSC;CCLE	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q15596	NCOA2	P28482	MAPK1	S736	K738R	738	Missense	proximal	2	no	16.880	17.061	PhosphoSitePlus	GDSC;CCLE	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q15596	NCOA2	P28482	MAPK1	S895	P888S	888	Missense	distal	-7	no	17.270	17.266	EPSD	GDSC;CCLE	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q15596	NCOA2	P28482	MAPK1	S895	Q894*	894	Missense	proximal	-1	no	17.270	17.200	EPSD	GDSC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P17676	CEBPB	P28482	MAPK1	S325	L327Q	327	Missense	proximal	2	no	8.611	8.581	EPSD	GDSC;CCLE	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P05198	EIF2S1	P28482	MAPK1	S26	I27T	27	Missense	proximal	1	no	9.629	10.949	EPSD	GDSC;CCLE	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P05198	EIF2S1	P28482	MAPK1	S52	R54W	54	Missense	proximal	2	no	8.103	7.735	PhosphoSitePlus	GDSC;CCLE	8.102	Loss
CMGC_MAPK_ERK1_MAPK1_ST	O60504	SORBS3	P28482	MAPK1	S28	R31P	31	Missense	distal	3	no	8.365	8.319	EPSD	GDSC;CCLE	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	O60504	SORBS3	P28482	MAPK1	S28	R34W	34	Missense	distal	6	no	8.365	7.442	EPSD	GDSC	8.102	Loss
CMGC_MAPK_ERK1_MAPK1_ST	O60504	SORBS3	P28482	MAPK1	S28	G32A	32	Missense	distal	4	no	8.365	8.321	EPSD	GDSC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	O60504	SORBS3	P28482	MAPK1	S30	R31P	31	Missense	proximal	1	no	5.159	14.813	EPSD	GDSC;CCLE	8.102	Gain
CMGC_MAPK_ERK1_MAPK1_ST	O60504	SORBS3	P28482	MAPK1	S339	A335T	335	Missense	distal	-4	no	13.401	13.381	EPSD	GDSC;CCLE	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	O60504	SORBS3	P28482	MAPK1	S339	S334F	334	Missense	distal	-5	no	13.401	13.489	EPSD	GDSC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	O60504	SORBS3	P28482	MAPK1	S339	R336P	336	Missense	distal	-3	no	13.401	13.420	EPSD	GDSC;CCLE	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	O60504	SORBS3	P28482	MAPK1	S373	A375T	375	Missense	proximal	2	no	13.044	13.123	EPSD	GDSC;CCLE	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	O60504	SORBS3	P28482	MAPK1	S373	S366N	366	Missense	distal	-7	no	13.044	13.046	EPSD	GDSC;CCLE	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	O60504	SORBS3	P28482	MAPK1	S395	Q392*	392	Missense	distal	-3	no	13.769	13.030	EPSD	GDSC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	O60504	SORBS3	P28482	MAPK1	S563	P564S	564	Missense	proximal	1	no	12.854	3.459	EPSD	GDSC;CCLE	8.102	Loss
CMGC_MAPK_ERK1_MAPK1_ST	O60504	SORBS3	P28482	MAPK1	S606	T609I	609	Missense	distal	3	no	14.445	14.510	EPSD	GDSC;CCLE	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	O60504	SORBS3	P28482	MAPK1	T615	T609I	609	Missense	distal	-6	no	13.835	13.758	EPSD	GDSC;CCLE	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q13480	GAB1	P28482	MAPK1	S264	D268N	268	Missense	distal	4	no	8.666	8.725	EPSD	GDSC;CCLE	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q13480	GAB1	P28482	MAPK1	S264	Y259H	259	Missense	distal	-5	no	8.666	8.585	EPSD	GDSC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q13480	GAB1	P28482	MAPK1	S274	D268N	268	Missense	distal	-6	no	13.799	13.754	EPSD	GDSC;CCLE	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q13480	GAB1	P28482	MAPK1	T289	T293A	293	Missense	distal	4	no	16.048	16.068	EPSD	GDSC;CCLE	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q13480	GAB1	P28482	MAPK1	T365	A366T	366	Missense	proximal	1	no	9.723	8.855	EPSD	GDSC;CCLE	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q13480	GAB1	P28482	MAPK1	T365	D370G	370	Missense	distal	5	no	9.723	9.679	EPSD	GDSC;CCLE	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q13480	GAB1	P28482	MAPK1	S367	A366T	366	Missense	proximal	-1	no	8.625	8.620	EPSD	GDSC;CCLE	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q13480	GAB1	P28482	MAPK1	S367	D370G	370	Missense	distal	3	no	8.625	8.623	EPSD	GDSC;CCLE	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q13480	GAB1	P28482	MAPK1	S367	C374R	374	Missense	distal	7	no	8.625	7.970	EPSD	GDSC;CCLE	8.102	Loss
CMGC_MAPK_ERK1_MAPK1_ST	Q13480	GAB1	P28482	MAPK1	T377	C374R	374	Missense	distal	-3	no	7.595	8.279	EPSD	GDSC;CCLE	8.102	Gain
CMGC_MAPK_ERK1_MAPK1_ST	Q13480	GAB1	P28482	MAPK1	S381	C374R	374	Missense	distal	-7	no	15.553	15.585	EPSD	GDSC;CCLE	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q13480	GAB1	P28482	MAPK1	S462	P466T	466	Missense	distal	4	no	8.166	8.042	EPSD	GDSC;CCLE	8.102	Loss
CMGC_MAPK_ERK1_MAPK1_ST	Q13480	GAB1	P28482	MAPK1	S500	T503P	503	Missense	distal	3	no	15.471	15.409	EPSD	GDSC;CCLE	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q13480	GAB1	P28482	MAPK1	T503	T503P	503	Missense	central	0	yes	16.804	0.000	EPSD	GDSC;CCLE	8.102	Loss
CMGC_MAPK_ERK1_MAPK1_ST	P10275	AR	P28482	MAPK1	S516	E523D	523	Missense	distal	7	no	13.880	13.935	PhosphoSitePlus	GDSC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q14934	NFATC4	P28482	MAPK1	S237	S237N	237	Missense	central	0	yes	13.770	0.000	EPSD	GDSC	8.102	Loss
CMGC_MAPK_ERK1_MAPK1_ST	P02686	MBP	P28482	MAPK1	T229	P235L	235	Missense	distal	6	no	15.846	15.440	EPSD	GDSC	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P02686	MBP	P28482	MAPK1	T232	P235L	235	Missense	distal	3	no	16.809	16.899	PhosphoSitePlus	GDSC	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q9UPT5	EXOC7	P28482	MAPK1	S250	V247I	247	Missense	distal	-3	no	17.902	17.768	PhosphoSitePlus	GDSC	8.102	Down-regulation
CMGC_GSK_GSK3B_ST	P49841	GSK3B	P49841-2	GSK3B	T7	T8P	8	Missense	proximal	1	no	4.452	7.643	EPSD	GDSC	6.007	Gain
CMGC_GSK_GSK3B_ST	P49841	GSK3B	P49841-2	GSK3B	S9	T8P	8	Missense	proximal	-1	no	6.632	6.763	EPSD	GDSC	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	P49841	GSK3B	P49841-2	GSK3B	S25	S21L	21	Missense	distal	-4	no	6.701	5.351	EPSD	GDSC;CCLE	6.007	Loss
CMGC_GSK_GSK3A_ST	P10636	MAPT	P49840	GSK3A	S46	Q49H	49	Missense	distal	3	no	87.831	93.676	EPSD	GDSC	72.838	Up-regulation
CMGC_GSK_GSK3A_ST	P10636	MAPT	P49840	GSK3A	S46	A41V	41	Missense	distal	-5	no	87.831	86.645	EPSD	GDSC;CCLE	72.838	Down-regulation
CMGC_GSK_GSK3A_ST	P10636	MAPT	P49840	GSK3A	T50	Q49H	49	Missense	proximal	-1	no	87.484	86.759	EPSD	GDSC	72.838	Down-regulation
CMGC_GSK_GSK3A_ST	P10636	MAPT	P49840	GSK3A	S171	D177V	177	Missense	distal	6	no	81.434	78.059	EPSD	GDSC	72.838	Down-regulation
CMGC_GSK_GSK3A_ST	P10636	MAPT	P49840	GSK3A	S227	R222H	222	Missense	distal	-5	no	77.653	77.854	EPSD	GDSC;CCLE	72.838	Up-regulation
CMGC_GSK_GSK3A_ST	P10636	MAPT	P49840	GSK3A	S228	R222H	222	Missense	distal	-6	no	92.623	92.398	EPSD	GDSC;CCLE	72.838	Down-regulation
CMGC_GSK_GSK3A_ST	P10636	MAPT	P49840	GSK3A	S341	P340L	340	Missense	proximal	-1	no	79.730	78.575	EPSD	GDSC;CCLE	72.838	Down-regulation
CMGC_GSK_GSK3A_ST	P10636	MAPT	P49840	GSK3A	S341	G339S	339	Missense	proximal	-2	no	79.730	80.470	EPSD	GDSC;CCLE	72.838	Up-regulation
CMGC_GSK_GSK3A_ST	P10636	MAPT	P49840	GSK3A	S355	E353D	353	Missense	proximal	-2	no	75.547	75.145	EPSD	GDSC;CCLE	72.838	Down-regulation
CMGC_GSK_GSK3A_ST	P10636	MAPT	P49840	GSK3A	T470	A475V	475	Missense	distal	5	no	87.288	85.676	EPSD	GDSC;CCLE	72.838	Down-regulation
CMGC_GSK_GSK3A_ST	P10636	MAPT	P49840	GSK3A	S641	V635I	635	Missense	distal	-6	no	77.110	76.663	EPSD	GDSC	72.838	Down-regulation
CMGC_GSK_GSK3A_ST	Q14449	GRB14	P49840	GSK3A	S370	N374K	374	Missense	distal	4	no	72.741	76.515	EPSD	GDSC	72.838	Gain
CMGC_GSK_GSK3A_ST	Q14449	GRB14	P49840	GSK3A	S370	V377I	377	Missense	distal	7	no	72.741	73.744	EPSD	GDSC;CCLE	72.838	Gain
CMGC_GSK_GSK3A_ST	Q14449	GRB14	P49840	GSK3A	S423	S427C	427	Missense	distal	4	no	78.862	5.449	EPSD;PhosphoSitePlus	GDSC;CCLE	72.838	Loss
CMGC_GSK_GSK3A_ST	Q14449	GRB14	P49840	GSK3A	S424	S427C	427	Missense	distal	3	no	88.602	84.288	EPSD	GDSC;CCLE	72.838	Down-regulation
CMGC_GSK_GSK3A_ST	O75581	LRP6	P49840	GSK3A	S1472	T1479I	1479	Missense	distal	7	no	72.983	72.290	EPSD	GDSC	72.838	Loss
CMGC_GSK_GSK3A_ST	O75581	LRP6	P49840	GSK3A	S1473	T1479I	1479	Missense	distal	6	no	81.508	79.080	EPSD	GDSC	72.838	Down-regulation
CMGC_GSK_GSK3A_ST	O75581	LRP6	P49840	GSK3A	S1490	R1495Q	1495	Missense	distal	5	no	88.879	83.625	EPSD	GDSC	72.838	Down-regulation
CMGC_GSK_GSK3A_ST	Q14596	NBR1	P49840	GSK3A	S123	T127N	127	Missense	distal	4	no	86.314	80.425	EPSD	GDSC	72.838	Down-regulation
CMGC_GSK_GSK3A_ST	Q14596	NBR1	P49840	GSK3A	S276	S273*	273	Missense	distal	-3	no	81.543	81.651	EPSD	GDSC	72.838	Up-regulation
CMGC_GSK_GSK3A_ST	Q14596	NBR1	P49840	GSK3A	S276	R279C	279	Missense	distal	3	no	81.543	76.943	EPSD	GDSC;CCLE	72.838	Down-regulation
CMGC_GSK_GSK3A_ST	Q14596	NBR1	P49840	GSK3A	S340	R347L	347	Missense	distal	7	no	77.016	76.929	EPSD	GDSC	72.838	Down-regulation
CMGC_GSK_GSK3A_ST	Q14596	NBR1	P49840	GSK3A	S486	E485D	485	Missense	proximal	-1	no	80.625	78.937	EPSD	GDSC;CCLE	72.838	Down-regulation
CMGC_GSK_GSK3A_ST	Q14596	NBR1	P49840	GSK3A	S833	V828I	828	Missense	distal	-5	no	80.995	79.857	EPSD	GDSC;CCLE	72.838	Down-regulation
CMGC_GSK_GSK3A_ST	P20749	BCL3	P49840	GSK3A	S122	M127T	127	Missense	distal	5	no	79.588	79.676	EPSD	GDSC;CCLE	72.838	Up-regulation
CMGC_GSK_GSK3A_ST	P20749	BCL3	P49840	GSK3A	S122	H119Q	119	Missense	distal	-3	no	79.588	78.509	EPSD	GDSC;CCLE	72.838	Down-regulation
CMGC_GSK_GSK3A_ST	P20749	BCL3	P49840	GSK3A	S402	S404C	404	Missense	proximal	2	no	97.336	94.589	PhosphoSitePlus;EPSD	GDSC;CCLE	72.838	Down-regulation
CMGC_GSK_GSK3A_ST	P20749	BCL3	P49840	GSK3A	S402	A397T	397	Missense	distal	-5	no	97.336	96.607	PhosphoSitePlus;EPSD	GDSC	72.838	Down-regulation
CMGC_GSK_GSK3A_ST	P20749	BCL3	P49840	GSK3A	S406	S404C	404	Missense	proximal	-2	no	104.218	103.077	EPSD;PhosphoSitePlus	GDSC;CCLE	72.838	Down-regulation
CMGC_GSK_GSK3A_ST	P22415	USF1	P49840	GSK3A	T195	R200H	200	Missense	distal	5	no	79.029	72.533	EPSD	GDSC;CCLE	72.838	Loss
CMGC_GSK_GSK3A_ST	Q96F46	IL17RA	P49840	GSK3A	S726	G729A	729	Missense	distal	3	no	83.451	84.700	EPSD	GDSC;CCLE	72.838	Up-regulation
CMGC_GSK_GSK3A_ST	Q96F46	IL17RA	P49840	GSK3A	T732	G729A	729	Missense	distal	-3	no	80.376	81.120	EPSD	GDSC;CCLE	72.838	Up-regulation
CMGC_GSK_GSK3A_ST	Q96F46	IL17RA	P49840	GSK3A	S736	P741S	741	Missense	distal	5	no	74.091	68.534	EPSD	GDSC;CCLE	72.838	Loss
CMGC_GSK_GSK3A_ST	Q96F46	IL17RA	P49840	GSK3A	S736	G729A	729	Missense	distal	-7	no	74.091	74.856	EPSD	GDSC;CCLE	72.838	Up-regulation
CMGC_GSK_GSK3A_ST	Q96F46	IL17RA	P49840	GSK3A	S801	Q794L	794	Missense	distal	-7	no	81.014	80.032	EPSD	GDSC;CCLE	72.838	Down-regulation
CMGC_GSK_GSK3A_ST	P17661	DES	P49840	GSK3A	T76	Y83H	83	Missense	distal	7	no	76.484	76.346	EPSD	GDSC	72.838	Down-regulation
CMGC_GSK_GSK3A_ST	P17661	DES	P49840	GSK3A	T76	S82T	82	Missense	distal	6	no	76.484	77.215	EPSD	GDSC	72.838	Up-regulation
CMGC_GSK_GSK3A_ST	P17661	DES	P49840	GSK3A	T77	Y83H	83	Missense	distal	6	no	71.196	73.412	EPSD	GDSC	72.838	Gain
CMGC_GSK_GSK3A_ST	P17661	DES	P49840	GSK3A	S81	S82T	82	Missense	proximal	1	no	71.822	72.863	EPSD	GDSC	72.838	Gain
CMGC_GSK_GSK3A_ST	P17661	DES	P49840	GSK3A	S330	C333*	333	Missense	distal	3	no	70.571	75.727	EPSD	GDSC	72.838	Gain
CMGC_GSK_GSK3A_ST	P17661	DES	P49840	GSK3A	T332	C333*	333	Missense	proximal	1	no	59.456	75.857	EPSD	GDSC	72.838	Gain
CMGC_GSK_GSK3A_ST	P35222	CTNNB1	P49840	GSK3A	T112	D115Y	115	Missense	distal	3	no	71.986	74.011	EPSD	GDSC;CCLE	72.838	Gain
CMGC_GSK_GSK3A_ST	P35222	CTNNB1	P49840	GSK3A	S179	H176Y	176	Missense	distal	-3	no	75.198	75.582	EPSD	GDSC;CCLE	72.838	Up-regulation
CMGC_GSK_GSK3A_ST	P35222	CTNNB1	P49840	GSK3A	T547	R549H	549	Missense	proximal	2	no	77.744	76.907	EPSD	GDSC;CCLE	72.838	Down-regulation
CMGC_GSK_GSK3A_ST	Q9Y6Q9	NCOA3	P49840	GSK3A	S465	P467Q	467	Missense	proximal	2	no	78.023	76.939	EPSD	GDSC	72.838	Down-regulation
CMGC_GSK_GSK3A_ST	Q9Y6Q9	NCOA3	P49840	GSK3A	S465	Y459H	459	Missense	distal	-6	no	78.023	78.219	EPSD	GDSC;CCLE	72.838	Up-regulation
CMGC_GSK_GSK3A_ST	Q9Y6Q9	NCOA3	P49840	GSK3A	S470	P467Q	467	Missense	distal	-3	no	88.413	87.171	EPSD	GDSC	72.838	Down-regulation
CMGC_GSK_GSK3A_ST	Q9Y6Q9	NCOA3	P49840	GSK3A	S636	P641S	641	Missense	distal	5	no	85.951	80.394	EPSD	GDSC;CCLE	72.838	Down-regulation
CMGC_GSK_GSK3A_ST	Q9Y6Q9	NCOA3	P49840	GSK3A	S640	P641S	641	Missense	proximal	1	no	93.688	77.996	EPSD	GDSC;CCLE	72.838	Down-regulation
CMGC_GSK_GSK3A_ST	Q9Y6Q9	NCOA3	P49840	GSK3A	S655	S657F	657	Missense	proximal	2	no	84.747	81.154	EPSD	GDSC;CCLE	72.838	Down-regulation
CMGC_GSK_GSK3A_ST	Q9Y6Q9	NCOA3	P49840	GSK3A	S660	S657F	657	Missense	distal	-3	no	75.606	74.377	EPSD	GDSC;CCLE	72.838	Down-regulation
CMGC_GSK_GSK3A_ST	Q9Y6Q9	NCOA3	P49840	GSK3A	S664	S657F	657	Missense	distal	-7	no	83.601	80.522	EPSD	GDSC;CCLE	72.838	Down-regulation
CMGC_GSK_GSK3A_ST	Q9Y6Q9	NCOA3	P49840	GSK3A	S728	V721I	721	Missense	distal	-7	no	86.863	85.981	EPSD	GDSC	72.838	Down-regulation
CMGC_GSK_GSK3A_ST	Q9Y6Q9	NCOA3	P49840	GSK3A	T912	S917L	917	Missense	distal	5	no	72.944	69.328	EPSD	GDSC	72.838	Loss
CMGC_GSK_GSK3A_ST	Q92597	NDRG1	P49840	GSK3A	S319	M320I	320	Missense	proximal	1	no	65.623	78.678	EPSD	GDSC	72.838	Gain
CMGC_GSK_GSK3A_ST	Q92597	NDRG1	P49840	GSK3A	T321	M320I	320	Missense	proximal	-1	no	77.377	76.097	EPSD	GDSC	72.838	Down-regulation
CMGC_GSK_GSK3A_ST	Q92597	NDRG1	P49840	GSK3A	S326	M320I	320	Missense	distal	-6	no	76.030	75.822	EPSD	GDSC	72.838	Down-regulation
CMGC_GSK_GSK3A_ST	P31749	AKT1	P49840	GSK3A	T312	K307N	307	Missense	distal	-5	no	84.746	85.008	EPSD;PhosphoSitePlus	GDSC;CCLE	72.838	Up-regulation
CMGC_GSK_GSK3A_ST	Q16584	MAP3K11	P49840	GSK3A	S419	A412V	412	Missense	distal	-7	no	82.735	81.861	EPSD	GDSC	72.838	Down-regulation
CMGC_GSK_GSK3A_ST	Q16584	MAP3K11	P49840	GSK3A	S674	T676R	676	Missense	proximal	2	no	89.853	88.645	EPSD	GDSC	72.838	Down-regulation
CMGC_GSK_GSK3A_ST	Q16584	MAP3K11	P49840	GSK3A	S674	P681S	681	Missense	distal	7	no	89.853	89.512	EPSD	GDSC	72.838	Down-regulation
CMGC_GSK_GSK3A_ST	Q16584	MAP3K11	P49840	GSK3A	T677	T676R	676	Missense	proximal	-1	no	82.147	80.166	EPSD	GDSC	72.838	Down-regulation
CMGC_GSK_GSK3A_ST	Q16584	MAP3K11	P49840	GSK3A	T677	P681S	681	Missense	distal	4	no	82.147	88.133	EPSD	GDSC	72.838	Up-regulation
CMGC_GSK_GSK3A_ST	Q16584	MAP3K11	P49840	GSK3A	T680	T676R	676	Missense	distal	-4	no	93.279	89.102	EPSD	GDSC	72.838	Down-regulation
CMGC_GSK_GSK3A_ST	Q16584	MAP3K11	P49840	GSK3A	T680	P681S	681	Missense	proximal	1	no	93.279	77.587	EPSD	GDSC	72.838	Down-regulation
CMGC_GSK_GSK3A_ST	Q16584	MAP3K11	P49840	GSK3A	S783	R787W	787	Missense	distal	4	no	80.056	69.285	EPSD	GDSC	72.838	Loss
CMGC_GSK_GSK3A_ST	Q16584	MAP3K11	P49840	GSK3A	S789	R787W	787	Missense	proximal	-2	no	103.622	101.460	PhosphoSitePlus;EPSD	GDSC	72.838	Down-regulation
CMGC_GSK_GSK3A_ST	Q16584	MAP3K11	P49840	GSK3A	S793	R787W	787	Missense	distal	-6	no	89.990	90.125	EPSD;PhosphoSitePlus	GDSC	72.838	Up-regulation
CMGC_GSK_GSK3A_ST	Q16584	MAP3K11	P49840	GSK3A	S815	A818P	818	Missense	distal	3	no	76.751	77.441	EPSD	GDSC	72.838	Up-regulation
CMGC_GSK_GSK3A_ST	O75030	MITF	P49840	GSK3A	S55	S52T	52	Missense	distal	-3	no	75.212	76.365	EPSD	GDSC;CCLE	72.838	Up-regulation
CMGC_GSK_GSK3A_ST	O75030	MITF	P49840	GSK3A	S176	P178R	178	Missense	proximal	2	no	73.322	72.836	EPSD	GDSC;CCLE	72.838	Loss
CMGC_GSK_GSK3A_ST	O75030	MITF	P49840	GSK3A	S180	P178R	178	Missense	proximal	-2	no	76.843	77.054	EPSD	GDSC;CCLE	72.838	Up-regulation
CMGC_GSK_GSK3A_ST	P24864	CCNE1	P49840	GSK3A	S103	S100C	100	Missense	distal	-3	no	79.511	78.624	EPSD	GDSC;CCLE	72.838	Down-regulation
CMGC_GSK_GSK3A_ST	P24864	CCNE1	P49840	GSK3A	S387	L394P	394	Missense	distal	7	no	74.609	75.573	EPSD	GDSC	72.838	Up-regulation
CMGC_GSK_GSK3A_ST	P24864	CCNE1	P49840	GSK3A	S391	L394P	394	Missense	distal	3	no	89.096	92.956	EPSD	GDSC	72.838	Up-regulation
CMGC_GSK_GSK3A_ST	P24864	CCNE1	P49840	GSK3A	T395	L394P	394	Missense	proximal	-1	no	86.429	87.584	PhosphoSitePlus	GDSC	72.838	Up-regulation
CMGC_GSK_GSK3A_ST	Q6R327	RICTOR	P49840	GSK3A	S1030	H1033Y	1033	Missense	distal	3	no	85.491	85.090	EPSD	GDSC	72.838	Down-regulation
CMGC_GSK_GSK3A_ST	Q6R327	RICTOR	P49840	GSK3A	S1031	H1033Y	1033	Missense	proximal	2	no	85.403	85.916	EPSD	GDSC	72.838	Up-regulation
CMGC_GSK_GSK3A_ST	Q6R327	RICTOR	P49840	GSK3A	S1035	H1033Y	1033	Missense	proximal	-2	no	73.166	73.307	EPSD	GDSC	72.838	Up-regulation
CMGC_GSK_GSK3A_ST	Q6R327	RICTOR	P49840	GSK3A	S1039	H1033Y	1033	Missense	distal	-6	no	72.949	72.752	EPSD	GDSC	72.838	Loss
CMGC_GSK_GSK3A_ST	Q6R327	RICTOR	P49840	GSK3A	T1148	Q1154P	1154	Missense	distal	6	no	83.010	81.100	EPSD	GDSC;CCLE	72.838	Down-regulation
CMGC_GSK_GSK3A_ST	Q6R327	RICTOR	P49840	GSK3A	S1235	G1242D	1242	Missense	distal	7	no	93.197	91.761	EPSD	GDSC;CCLE	72.838	Down-regulation
CMGC_GSK_GSK3A_ST	Q6R327	RICTOR	P49840	GSK3A	S1237	G1242D	1242	Missense	distal	5	no	73.549	72.270	EPSD	GDSC;CCLE	72.838	Loss
CMGC_GSK_GSK3A_ST	Q6R327	RICTOR	P49840	GSK3A	S1407	R1405*	1405	Missense	proximal	-2	no	76.082	75.161	EPSD	GDSC	72.838	Down-regulation
CMGC_GSK_GSK3A_ST	P17812	CTPS1	P49840	GSK3A	S311	Y307H	307	Missense	distal	-4	no	77.066	77.542	EPSD	GDSC;CCLE	72.838	Up-regulation
CMGC_GSK_GSK3A_ST	P17812	CTPS1	P49840	GSK3A	S311	S311*	311	Missense	central	0	yes	77.066	0.000	EPSD	GDSC	72.838	Loss
CMGC_GSK_GSK3A_ST	P17812	CTPS1	P49840	GSK3A	T459	M464T	464	Missense	distal	5	no	73.104	73.191	EPSD	GDSC;CCLE	72.838	Up-regulation
CMGC_GSK_GSK3A_ST	Q9BYG3	NIFK	P49840	GSK3A	S247	S247C	247	Missense	central	0	yes	73.800	0.000	EPSD	GDSC	72.838	Loss
CMGC_GSK_GSK3A_ST	Q9BYG3	NIFK	P49840	GSK3A	T279	Q275K	275	Missense	distal	-4	no	91.695	94.653	EPSD	GDSC	72.838	Up-regulation
CMGC_GSK_GSK3A_ST	Q13563	PKD2	P49840	GSK3A	S802	S804N	804	Missense	proximal	2	no	73.096	70.534	EPSD	GDSC	72.838	Loss
CMGC_GSK_GSK3A_ST	Q13563	PKD2	P49840	GSK3A	S804	S804N	804	Missense	central	0	yes	75.424	0.000	EPSD	GDSC	72.838	Loss
CMGC_GSK_GSK3A_ST	Q13563	PKD2	P49840	GSK3A	S808	S804N	804	Missense	distal	-4	no	78.504	75.932	EPSD	GDSC	72.838	Down-regulation
CMGC_GSK_GSK3A_ST	Q13563	PKD2	P49840	GSK3A	S949	E956K	956	Missense	distal	7	no	77.361	77.506	EPSD	GDSC	72.838	Up-regulation
CMGC_GSK_GSK3A_ST	Q07817	BCL2L1	P49840	GSK3A	S62	P55S	55	Missense	distal	-7	no	89.682	89.527	PhosphoSitePlus	GDSC;CCLE	72.838	Down-regulation
CMGC_GSK_GSK3A_ST	Q07817	BCL2L1	P49840	GSK3A	S62	T69I	69	Missense	distal	7	no	89.682	88.989	PhosphoSitePlus	GDSC;CCLE	72.838	Down-regulation
CMGC_GSK_GSK3A_ST	Q07817	BCL2L1	P49840	GSK3A	S62	G67V	67	Missense	distal	5	no	89.682	87.184	PhosphoSitePlus	GDSC;CCLE	72.838	Down-regulation
CMGC_GSK_GSK3A_ST	Q9Y4H4	GPSM3	P49840	GSK3A	T86	T86P	86	Missense	central	0	yes	73.753	0.000	EPSD	GDSC	72.838	Loss
CMGC_GSK_GSK3A_ST	Q16555	DPYSL2	P49840	GSK3A	T521	Q526*	526	Missense	distal	5	no	74.940	79.888	EPSD	GDSC	72.838	Up-regulation
CMGC_GSK_GSK3A_ST	Q16555	DPYSL2	P49840	GSK3A	S522	Q526*	526	Missense	distal	4	no	63.027	74.106	EPSD	GDSC	72.838	Gain
CMGC_GSK_GSK3A_ST	Q16555	DPYSL2	P49840	GSK3A	S537	P530A	530	Missense	distal	-7	no	81.239	82.042	EPSD	GDSC;CCLE	72.838	Up-regulation
Atypical_PDHK_PDHK_PDK2_ST	P08559	PDHA1	Q15119	PDK2	S152	M155I	155	Missense	distal	3	no	2.232	2.230	EPSD	GDSC;CCLE	1.129	Down-regulation
Atypical_PDHK_PDHK_PDK2_ST	P29803	PDHA2	Q15119	PDK2	S128	V121L	121	Missense	distal	-7	no	1.535	1.599	EPSD	GDSC	1.129	Up-regulation
Atypical_PDHK_PDHK_PDK2_ST	P29803	PDHA2	Q15119	PDK2	S128	R130P	130	Missense	proximal	2	no	1.535	1.568	EPSD	GDSC;CCLE	1.129	Up-regulation
Atypical_PDHK_PDHK_PDK2_ST	P29803	PDHA2	Q15119	PDK2	S150	G146R	146	Missense	distal	-4	no	2.111	2.055	EPSD	GDSC;CCLE	1.129	Down-regulation
Atypical_PDHK_PDHK_PDK2_ST	P29803	PDHA2	Q15119	PDK2	S230	E232K	232	Missense	proximal	2	no	2.450	2.428	EPSD	GDSC;CCLE	1.129	Down-regulation
Atypical_PDHK_PDHK_PDK2_ST	P29803	PDHA2	Q15119	PDK2	T284	P277H	277	Missense	distal	-7	no	1.160	1.092	EPSD	GDSC;CCLE	1.129	Loss
Atypical_PDHK_PDHK_PDK2_ST	P29803	PDHA2	Q15119	PDK2	S291	V297F	297	Missense	distal	6	no	4.883	4.755	EPSD;PhosphoSitePlus	GDSC;CCLE	1.129	Down-regulation
CAMK_TSSK_TSSK4_ST	P16220	CREB1	Q6SA08	TSSK4	S111	S111L	111	Missense	central	0	yes	1.918	0.000	EPSD	GDSC;CCLE	1.711	Loss
CAMK_TSSK_TSSK4_ST	P16220	CREB1	Q6SA08	TSSK4	T251	Y252*	252	Missense	proximal	1	no	2.528	1.113	EPSD	GDSC	1.711	Loss
CAMK_TSSK_TSSK4_ST	P16220	CREB1	Q6SA08	TSSK4	T259	Y252*	252	Missense	distal	-7	no	2.835	2.853	EPSD	GDSC	1.711	Up-regulation
TK_Met_MET_Y	P09874	PARP1	P08581	MET	Y907	H909N	909	Missense	proximal	2	no	35.103	35.369	PhosphoSitePlus	GDSC;CCLE	27.257	Up-regulation
TK_Met_MET_Y	Q04912	MST1R	P08581	MET	Y1353	Y1360C	1360	Missense	distal	7	no	46.732	46.671	PhosphoSitePlus;EPSD	GDSC;CCLE	27.257	Down-regulation
TK_Met_MET_Y	Q04912	MST1R	P08581	MET	Y1360	Y1360C	1360	Missense	central	0	yes	30.446	0.000	EPSD;PhosphoSitePlus	GDSC;CCLE	27.257	Loss
TK_Met_MET_Y	P35568	IRS1	P08581	MET	Y551	A546V	546	Missense	distal	-5	no	40.727	38.836	EPSD	GDSC;CCLE	27.257	Down-regulation
TK_Met_MET_Y	P35568	IRS1	P08581	MET	Y695	V689I	689	Missense	distal	-6	no	33.992	34.149	EPSD	GDSC	27.257	Up-regulation
TK_Met_MET_Y	P35568	IRS1	P08581	MET	Y732	P737S	737	Missense	distal	5	no	36.487	36.700	EPSD	GDSC	27.257	Up-regulation
TK_Met_MET_Y	P35568	IRS1	P08581	MET	Y750	D755A	755	Missense	distal	5	no	54.834	54.893	EPSD	GDSC	27.257	Up-regulation
TK_Met_MET_Y	Q05397	PTK2	P08581	MET	Y407	T406I	406	Missense	proximal	-1	no	72.144	69.266	EPSD;PhosphoSitePlus	GDSC;CCLE	27.257	Down-regulation
TK_Met_MET_Y	Q05397	PTK2	P08581	MET	Y407	P410H	410	Missense	distal	3	no	72.144	61.938	EPSD;PhosphoSitePlus	GDSC;CCLE	27.257	Down-regulation
TK_Met_MET_Y	P06213	INSR	P08581	MET	Y1011	D1014E	1014	Missense	distal	3	no	25.300	28.019	EPSD	GDSC;CCLE	27.257	Gain
CMGC_DYRK_DYRK1_DYRK1A_ST	P10636	MAPT	Q13627	DYRK1A	T50	Q49H	49	Missense	proximal	-1	no	39.232	39.357	EPSD	GDSC	34.163	Up-regulation
CMGC_DYRK_DYRK1_DYRK1A_ST	P10636	MAPT	Q13627	DYRK1A	S171	D177V	177	Missense	distal	6	no	40.913	40.939	EPSD	GDSC	34.163	Up-regulation
CMGC_DYRK_DYRK1_DYRK1A_ST	P10636	MAPT	Q13627	DYRK1A	T173	D177V	177	Missense	distal	4	no	40.645	41.740	EPSD	GDSC	34.163	Up-regulation
CMGC_DYRK_DYRK1_DYRK1A_ST	P10636	MAPT	Q13627	DYRK1A	S214	V218G	218	Missense	distal	4	no	45.770	43.268	EPSD	GDSC	34.163	Down-regulation
CMGC_DYRK_DYRK1_DYRK1A_ST	P10636	MAPT	Q13627	DYRK1A	S228	R222H	222	Missense	distal	-6	no	47.818	47.201	EPSD	GDSC;CCLE	34.163	Down-regulation
CMGC_DYRK_DYRK1_DYRK1A_ST	P10636	MAPT	Q13627	DYRK1A	S637	V635I	635	Missense	proximal	-2	no	35.842	32.644	EPSD	GDSC	34.163	Loss
CMGC_DYRK_DYRK1_DYRK1A_ST	P10636	MAPT	Q13627	DYRK1A	S739	S739C	739	Missense	central	0	yes	49.406	0.000	EPSD	GDSC	34.163	Loss
CMGC_DYRK_DYRK1_DYRK1A_ST	P49418	AMPH	Q13627	DYRK1A	T260	I257F	257	Missense	distal	-3	no	38.916	22.315	EPSD	GDSC;CCLE	34.163	Loss
CMGC_DYRK_DYRK1_DYRK1A_ST	P49418	AMPH	Q13627	DYRK1A	T260	P261T	261	Missense	proximal	1	no	38.916	16.538	EPSD	GDSC;CCLE	34.163	Loss
CMGC_DYRK_DYRK1_DYRK1A_ST	P49418	AMPH	Q13627	DYRK1A	S262	I257F	257	Missense	distal	-5	no	45.398	44.421	EPSD	GDSC;CCLE	34.163	Down-regulation
CMGC_DYRK_DYRK1_DYRK1A_ST	P49418	AMPH	Q13627	DYRK1A	S262	P261T	261	Missense	proximal	-1	no	45.398	44.749	EPSD	GDSC;CCLE	34.163	Down-regulation
CMGC_DYRK_DYRK1_DYRK1A_ST	P49418	AMPH	Q13627	DYRK1A	S272	P277S	277	Missense	distal	5	no	34.885	34.946	EPSD	GDSC	34.163	Up-regulation
CMGC_DYRK_DYRK1_DYRK1A_ST	P49418	AMPH	Q13627	DYRK1A	S272	L270F	270	Missense	proximal	-2	no	34.885	35.772	EPSD	GDSC;CCLE	34.163	Up-regulation
CMGC_DYRK_DYRK1_DYRK1A_ST	P49418	AMPH	Q13627	DYRK1A	S285	R292Q	292	Missense	distal	7	no	36.285	37.746	EPSD	GDSC;CCLE	34.163	Up-regulation
CMGC_DYRK_DYRK1_DYRK1A_ST	P49418	AMPH	Q13627	DYRK1A	S293	R292Q	292	Missense	proximal	-1	no	65.700	66.230	EPSD;PhosphoSitePlus	GDSC;CCLE	34.163	Up-regulation
CMGC_DYRK_DYRK1_DYRK1A_ST	P49418	AMPH	Q13627	DYRK1A	S295	P302T	302	Missense	distal	7	no	53.995	54.666	EPSD;PhosphoSitePlus	GDSC;CCLE	34.163	Up-regulation
CMGC_DYRK_DYRK1_DYRK1A_ST	P49418	AMPH	Q13627	DYRK1A	S295	R292Q	292	Missense	distal	-3	no	53.995	40.243	EPSD;PhosphoSitePlus	GDSC;CCLE	34.163	Down-regulation
CMGC_DYRK_DYRK1_DYRK1A_ST	P49418	AMPH	Q13627	DYRK1A	T310	T310N	310	Missense	central	0	yes	53.226	0.000	PhosphoSitePlus;EPSD	GDSC;CCLE	34.163	Loss
CMGC_DYRK_DYRK1_DYRK1A_ST	P49418	AMPH	Q13627	DYRK1A	T310	P304Q	304	Missense	distal	-6	no	53.226	53.079	PhosphoSitePlus;EPSD	GDSC;CCLE	34.163	Down-regulation
CMGC_DYRK_DYRK1_DYRK1A_ST	P49418	AMPH	Q13627	DYRK1A	T312	T310N	310	Missense	proximal	-2	no	51.793	34.400	EPSD;PhosphoSitePlus	GDSC;CCLE	34.163	Down-regulation
CMGC_DYRK_DYRK1_DYRK1A_ST	P49418	AMPH	Q13627	DYRK1A	T498	V505I	505	Missense	distal	7	no	35.201	35.153	EPSD	GDSC;CCLE	34.163	Down-regulation
CMGC_DYRK_DYRK1_DYRK1A_ST	P53805	RCAN1	Q13627	DYRK1A	S167	S163C	163	Missense	distal	-4	no	60.157	60.144	EPSD;PhosphoSitePlus	GDSC;CCLE	34.163	Down-regulation
CMGC_DYRK_DYRK1_DYRK1A_ST	P53805	RCAN1	Q13627	DYRK1A	T247	T241S	241	Missense	distal	-6	no	45.164	45.518	PhosphoSitePlus;EPSD	GDSC;CCLE	34.163	Up-regulation
CMGC_DYRK_DYRK1_DYRK1A_ST	P24928	POLR2A	Q13627	DYRK1A	S1571	P1569L	1569	Missense	proximal	-2	no	38.122	24.394	EPSD	GDSC;CCLE	34.163	Loss
CMGC_DYRK_DYRK1_DYRK1A_ST	P24928	POLR2A	Q13627	DYRK1A	S1571	T1568S	1568	Missense	distal	-3	no	38.122	47.141	EPSD	GDSC;CCLE	34.163	Up-regulation
CMGC_DYRK_DYRK1_DYRK1A_ST	P24928	POLR2A	Q13627	DYRK1A	S1574	P1569L	1569	Missense	distal	-5	no	45.919	44.483	EPSD	GDSC;CCLE	34.163	Down-regulation
CMGC_DYRK_DYRK1_DYRK1A_ST	P24928	POLR2A	Q13627	DYRK1A	S1574	T1568S	1568	Missense	distal	-6	no	45.919	46.274	EPSD	GDSC;CCLE	34.163	Up-regulation
CMGC_DYRK_DYRK1_DYRK1A_ST	P24928	POLR2A	Q13627	DYRK1A	S1616	S1616F	1616	Missense	central	0	yes	50.699	0.000	PhosphoSitePlus;EPSD	GDSC;CCLE	34.163	Loss
CMGC_DYRK_DYRK1_DYRK1A_ST	P24928	POLR2A	Q13627	DYRK1A	S1619	S1616F	1616	Missense	distal	-3	no	51.765	32.592	EPSD;PhosphoSitePlus	GDSC;CCLE	34.163	Loss
CMGC_DYRK_DYRK1_DYRK1A_ST	P24928	POLR2A	Q13627	DYRK1A	S1766	P1764L	1764	Missense	proximal	-2	no	36.827	23.100	EPSD	GDSC;CCLE	34.163	Loss
CMGC_DYRK_DYRK1_DYRK1A_ST	P24928	POLR2A	Q13627	DYRK1A	S1847	Y1853H	1853	Missense	distal	6	no	40.415	40.367	EPSD	GDSC;CCLE	34.163	Down-regulation
CMGC_DYRK_DYRK1_DYRK1A_ST	P24928	POLR2A	Q13627	DYRK1A	S1850	Y1853H	1853	Missense	distal	3	no	44.410	44.391	EPSD	GDSC;CCLE	34.163	Down-regulation
CMGC_DYRK_DYRK1_DYRK1A_ST	P24928	POLR2A	Q13627	DYRK1A	T1854	Y1853H	1853	Missense	proximal	-1	no	40.096	38.635	EPSD	GDSC;CCLE	34.163	Down-regulation
CMGC_DYRK_DYRK1_DYRK1A_ST	P24928	POLR2A	Q13627	DYRK1A	S1861	P1862T	1862	Missense	proximal	1	no	37.943	15.565	EPSD	GDSC;CCLE	34.163	Loss
CMGC_DYRK_DYRK1_DYRK1A_ST	P24928	POLR2A	Q13627	DYRK1A	S1864	P1862T	1862	Missense	proximal	-2	no	45.115	39.879	EPSD	GDSC;CCLE	34.163	Down-regulation
CMGC_DYRK_DYRK1_DYRK1A_ST	P24928	POLR2A	Q13627	DYRK1A	S1868	P1862T	1862	Missense	distal	-6	no	42.674	43.023	EPSD	GDSC;CCLE	34.163	Up-regulation
CMGC_DYRK_DYRK1_DYRK1A_ST	P24928	POLR2A	Q13627	DYRK1A	S1962	I1961V	1961	Missense	proximal	-1	no	35.682	35.603	EPSD	GDSC;CCLE	34.163	Down-regulation
CMGC_DYRK_DYRK1_DYRK1A_ST	P08151	GLI1	Q13627	DYRK1A	S84	P87S	87	Missense	distal	3	no	50.733	51.255	EPSD	GDSC;CCLE	34.163	Up-regulation
CMGC_DYRK_DYRK1_DYRK1A_ST	P08151	GLI1	Q13627	DYRK1A	S545	R542C	542	Missense	distal	-3	no	47.505	24.000	EPSD	GDSC;CCLE	34.163	Loss
CMGC_DYRK_DYRK1_DYRK1A_ST	P08151	GLI1	Q13627	DYRK1A	S545	S545G	545	Missense	central	0	yes	47.505	0.000	EPSD	GDSC;CCLE	34.163	Loss
CMGC_DYRK_DYRK1_DYRK1A_ST	P08151	GLI1	Q13627	DYRK1A	S602	G600C	600	Missense	proximal	-2	no	44.149	37.723	EPSD	GDSC	34.163	Down-regulation
CMGC_DYRK_DYRK1_DYRK1A_ST	P08151	GLI1	Q13627	DYRK1A	S640	Q644R	644	Missense	distal	4	no	43.812	41.556	EPSD	GDSC;CCLE	34.163	Down-regulation
CMGC_DYRK_DYRK1_DYRK1A_ST	P08151	GLI1	Q13627	DYRK1A	S937	V936I	936	Missense	proximal	-1	no	44.905	44.984	EPSD	GDSC;CCLE	34.163	Up-regulation
CMGC_DYRK_DYRK1_DYRK1A_ST	P08151	GLI1	Q13627	DYRK1A	S939	V936I	936	Missense	distal	-3	no	39.170	37.281	EPSD	GDSC;CCLE	34.163	Down-regulation
CMGC_DYRK_DYRK1_DYRK1A_ST	Q13627	DYRK1A	Q13627	DYRK1A	S14	S14C	14	Missense	central	0	yes	40.592	0.000	EPSD	GDSC;CCLE	34.163	Loss
CMGC_DYRK_DYRK1_DYRK1A_ST	Q13627	DYRK1A	Q13627	DYRK1A	S529	H533Y	533	Missense	distal	4	no	52.145	53.858	PhosphoSitePlus	GDSC;CCLE	34.163	Up-regulation
CMGC_DYRK_DYRK1_DYRK1A_ST	Q13627	DYRK1A	Q13627	DYRK1A	S529	T532M	532	Missense	distal	3	no	52.145	52.311	PhosphoSitePlus	GDSC	34.163	Up-regulation
CMGC_DYRK_DYRK1_DYRK1A_ST	Q13627	DYRK1A	Q13627	DYRK1A	S758	T751S	751	Missense	distal	-7	no	37.400	37.620	EPSD	GDSC	34.163	Up-regulation
CMGC_DYRK_DYRK1_DYRK1A_ST	O95644	NFATC1	Q13627	DYRK1A	S278	P275L	275	Missense	distal	-3	no	55.224	53.230	EPSD;PhosphoSitePlus	GDSC	34.163	Down-regulation
CMGC_DYRK_DYRK1_DYRK1A_ST	O75533	SF3B1	Q13627	DYRK1A	T261	A263V	263	Missense	proximal	2	no	45.422	44.251	EPSD	GDSC	34.163	Down-regulation
CMGC_DYRK_DYRK1_DYRK1A_ST	O75533	SF3B1	Q13627	DYRK1A	T267	T273A	273	Missense	distal	6	no	47.765	47.810	EPSD	GDSC;CCLE	34.163	Up-regulation
CMGC_DYRK_DYRK1_DYRK1A_ST	O75533	SF3B1	Q13627	DYRK1A	T267	A263V	263	Missense	distal	-4	no	47.765	47.725	EPSD	GDSC	34.163	Down-regulation
CMGC_DYRK_DYRK1_DYRK1A_ST	O75533	SF3B1	Q13627	DYRK1A	T273	T273A	273	Missense	central	0	yes	54.664	0.000	PhosphoSitePlus;EPSD	GDSC;CCLE	34.163	Loss
CMGC_DYRK_DYRK1_DYRK1A_ST	O75533	SF3B1	Q13627	DYRK1A	T278	T273A	273	Missense	distal	-5	no	35.001	35.009	EPSD	GDSC;CCLE	34.163	Up-regulation
CMGC_DYRK_DYRK1_DYRK1A_ST	O75533	SF3B1	Q13627	DYRK1A	S1271	Y1269F	1269	Missense	proximal	-2	no	43.021	36.679	EPSD	GDSC;CCLE	34.163	Down-regulation
CMGC_DYRK_DYRK1_DYRK1A_ST	Q96S94	CCNL2	Q13627	DYRK1A	S25	G26E	26	Missense	proximal	1	no	41.427	37.020	EPSD	GDSC;CCLE	34.163	Down-regulation
CMGC_DYRK_DYRK1_DYRK1A_ST	Q96S94	CCNL2	Q13627	DYRK1A	S25	S25C	25	Missense	central	0	yes	41.427	0.000	EPSD	GDSC	34.163	Loss
CMGC_DYRK_DYRK1_DYRK1A_ST	Q96S94	CCNL2	Q13627	DYRK1A	S32	D39N	39	Missense	distal	7	no	43.486	44.575	EPSD	GDSC;CCLE	34.163	Up-regulation
CMGC_DYRK_DYRK1_DYRK1A_ST	Q96S94	CCNL2	Q13627	DYRK1A	S32	G26E	26	Missense	distal	-6	no	43.486	43.716	EPSD	GDSC;CCLE	34.163	Up-regulation
CMGC_DYRK_DYRK1_DYRK1A_ST	Q96S94	CCNL2	Q13627	DYRK1A	S32	S25C	25	Missense	distal	-7	no	43.486	44.385	EPSD	GDSC	34.163	Up-regulation
CMGC_DYRK_DYRK1_DYRK1A_ST	Q96S94	CCNL2	Q13627	DYRK1A	S394	S390C	390	Missense	distal	-4	no	38.187	38.174	EPSD	GDSC;CCLE	34.163	Down-regulation
CMGC_DYRK_DYRK1_DYRK1A_ST	Q96S94	CCNL2	Q13627	DYRK1A	S415	R422Q	422	Missense	distal	7	no	32.833	34.294	EPSD	GDSC;CCLE	34.163	Gain
CMGC_DYRK_DYRK1_DYRK1A_ST	Q96S94	CCNL2	Q13627	DYRK1A	S417	R422Q	422	Missense	distal	5	no	37.137	38.128	EPSD	GDSC;CCLE	34.163	Up-regulation
CMGC_DYRK_DYRK1_DYRK1A_ST	Q96S94	CCNL2	Q13627	DYRK1A	S423	R422Q	422	Missense	proximal	-1	no	35.042	35.573	EPSD	GDSC;CCLE	34.163	Up-regulation
CMGC_DYRK_DYRK1_DYRK1A_ST	Q96S94	CCNL2	Q13627	DYRK1A	S427	R422Q	422	Missense	distal	-5	no	57.911	56.759	EPSD	GDSC;CCLE	34.163	Down-regulation
CMGC_DYRK_DYRK1_DYRK1A_ST	Q52LA3	LIN52	Q13627	DYRK1A	S28	R26C	26	Missense	proximal	-2	no	53.810	40.690	PhosphoSitePlus	GDSC;CCLE	34.163	Down-regulation
CMGC_DYRK_DYRK1_DYRK1A_ST	O43597	SPRY2	Q13627	DYRK1A	T75	Q76*	76	Missense	proximal	1	no	54.771	31.122	PhosphoSitePlus	GDSC	34.163	Loss
CMGC_DYRK_DYRK1_DYRK1A_ST	P04637	TP53	Q13627	DYRK1A	S33	Q38*	38	Missense	distal	5	no	34.790	29.440	EPSD	GDSC	34.163	Loss
CMGC_DYRK_DYRK1_DYRK1A_ST	P04637	TP53	Q13627	DYRK1A	T81	A74S	74	Missense	distal	-7	no	42.596	42.218	EPSD	GDSC;CCLE	34.163	Down-regulation
CMGC_DYRK_DYRK1_DYRK1A_ST	P04637	TP53	Q13627	DYRK1A	S99	K101*	101	Missense	proximal	2	no	36.467	35.169	EPSD	GDSC	34.163	Down-regulation
CMGC_DYRK_DYRK1_DYRK1A_ST	P04637	TP53	Q13627	DYRK1A	S99	Q100*	100	Missense	proximal	1	no	36.467	12.818	EPSD	GDSC	34.163	Loss
CMGC_DYRK_DYRK1_DYRK1A_ST	P04637	TP53	Q13627	DYRK1A	S99	S94*	94	Missense	distal	-5	no	36.467	35.728	EPSD	GDSC	34.163	Down-regulation
CMGC_DYRK_DYRK1_DYRK1A_ST	P04637	TP53	Q13627	DYRK1A	S127	Y126*	126	Missense	proximal	-1	no	37.482	37.025	EPSD	GDSC	34.163	Down-regulation
CMGC_DYRK_DYRK1_DYRK1A_ST	P04637	TP53	Q13627	DYRK1A	S127	K120*	120	Missense	distal	-7	no	37.482	38.947	EPSD	GDSC	34.163	Up-regulation
CMGC_DYRK_DYRK1_DYRK1A_ST	P04637	TP53	Q13627	DYRK1A	T304	R306*	306	Missense	proximal	2	no	36.536	35.246	EPSD	GDSC	34.163	Down-regulation
CMGC_DYRK_DYRK1_DYRK1A_ST	P04637	TP53	Q13627	DYRK1A	T304	E298*	298	Missense	distal	-6	no	36.536	35.309	EPSD	GDSC	34.163	Down-regulation
CMGC_DYRK_DYRK1_DYRK1A_ST	P04637	TP53	Q13627	DYRK1A	S315	Q317*	317	Missense	proximal	2	no	40.613	39.513	EPSD	GDSC	34.163	Down-regulation
CMGC_DYRK_DYRK1_DYRK1A_ST	P04637	TP53	Q13627	DYRK1A	S315	K319*	319	Missense	distal	4	no	40.613	41.868	EPSD	GDSC	34.163	Up-regulation
CMGC_DYRK_DYRK1_DYRK1A_ST	Q12778	FOXO1	Q13627	DYRK1A	S329	T333A	333	Missense	distal	4	no	54.730	54.516	PhosphoSitePlus	GDSC;CCLE	34.163	Down-regulation
CMGC_DYRK_DYRK1_DYRK1A_ST	O76039	CDKL5	Q13627	DYRK1A	S529	P527S	527	Missense	proximal	-2	no	51.791	46.854	EPSD	GDSC;CCLE	34.163	Down-regulation
CMGC_DYRK_DYRK1_DYRK1A_ST	O76039	CDKL5	Q13627	DYRK1A	T531	P527S	527	Missense	distal	-4	no	36.608	36.610	EPSD	GDSC;CCLE	34.163	Up-regulation
CMGC_DYRK_DYRK1_DYRK1A_ST	O76039	CDKL5	Q13627	DYRK1A	S790	Q791P	791	Missense	proximal	1	no	22.277	34.941	EPSD	GDSC	34.163	Gain
CMGC_DYRK_DYRK1_DYRK1A_ST	O76039	CDKL5	Q13627	DYRK1A	T813	S810F	810	Missense	distal	-3	no	36.353	17.180	EPSD	GDSC;CCLE	34.163	Loss
CMGC_DYRK_DYRK1_DYRK1A_ST	O76039	CDKL5	Q13627	DYRK1A	T813	K819N	819	Missense	distal	6	no	36.353	36.344	EPSD	GDSC;CCLE	34.163	Down-regulation
CMGC_DYRK_DYRK1_DYRK1A_ST	Q05193	DNM1	Q13627	DYRK1A	S116	N121S	121	Missense	distal	5	no	32.587	35.521	EPSD	GDSC;CCLE	34.163	Gain
CMGC_DYRK_DYRK1_DYRK1A_ST	Q05193	DNM1	Q13627	DYRK1A	S126	N121S	121	Missense	distal	-5	no	38.404	39.775	EPSD	GDSC;CCLE	34.163	Up-regulation
CMGC_DYRK_DYRK1_DYRK1A_ST	Q05193	DNM1	Q13627	DYRK1A	S774	R772H	772	Missense	proximal	-2	no	40.955	29.534	EPSD	GDSC;CCLE	34.163	Loss
CMGC_DYRK_DYRK1_DYRK1A_ST	Q05193	DNM1	Q13627	DYRK1A	S778	R772H	772	Missense	distal	-6	no	59.567	58.950	EPSD	GDSC;CCLE	34.163	Down-regulation
CMGC_DYRK_DYRK1_DYRK1A_ST	Q05193	DNM1	Q13627	DYRK1A	S857	D863Y	863	Missense	distal	6	no	64.607	64.642	PhosphoSitePlus	GDSC;CCLE	34.163	Up-regulation
CMGC_DYRK_HIPK_HIPK1_ST	P51608	MECP2	Q86Z02	HIPK1	S401	P405A	405	Missense	distal	4	no	3.090	3.061	EPSD	GDSC	1.785	Down-regulation
CMGC_DYRK_HIPK_HIPK1_ST	P51608	MECP2	Q86Z02	HIPK1	S411	P405A	405	Missense	distal	-6	no	2.343	2.252	EPSD	GDSC	1.785	Down-regulation
Other_NEK_NEK11_NEK11_ST	P30304	CDC25A	Q8NG66	NEK11	S76	G75C	75	Missense	proximal	-1	no	3.375	3.239	EPSD	GDSC;CCLE	2.788	Down-regulation
Other_NEK_NEK11_NEK11_ST	P30304	CDC25A	Q8NG66	NEK11	S79	G75C	75	Missense	distal	-4	no	9.118	8.798	EPSD;PhosphoSitePlus	GDSC;CCLE	2.788	Down-regulation
Other_NEK_NEK11_NEK11_ST	P30304	CDC25A	Q8NG66	NEK11	S82	G75C	75	Missense	distal	-7	no	9.075	9.068	EPSD;PhosphoSitePlus	GDSC;CCLE	2.788	Down-regulation
Other_NEK_NEK11_NEK11_ST	P30304	CDC25A	Q8NG66	NEK11	S293	S287N	287	Missense	distal	-6	no	3.687	3.618	EPSD	GDSC	2.788	Down-regulation
Other_NEK_NEK11_NEK11_ST	P30304	CDC25A	Q8NG66	NEK11	S320	A319V	319	Missense	proximal	-1	no	3.121	3.021	EPSD	GDSC;CCLE	2.788	Down-regulation
Other_NEK_NEK11_NEK11_ST	P30304	CDC25A	Q8NG66	NEK11	S320	Q314*	314	Missense	distal	-6	no	3.121	2.996	EPSD	GDSC	2.788	Down-regulation
Other_NEK_NEK11_NEK11_ST	P54132	BLM	Q8NG66	NEK11	S17	R15H	15	Missense	proximal	-2	no	3.432	3.451	EPSD	GDSC;CCLE	2.788	Up-regulation
Other_NEK_NEK11_NEK11_ST	P54132	BLM	Q8NG66	NEK11	S28	S28L	28	Missense	central	0	yes	3.082	0.000	EPSD	GDSC;CCLE	2.788	Loss
Other_NEK_NEK11_NEK11_ST	P54132	BLM	Q8NG66	NEK11	S144	T150A	150	Missense	distal	6	no	3.260	3.287	EPSD	GDSC;CCLE	2.788	Up-regulation
Other_NEK_NEK11_NEK11_ST	P54132	BLM	Q8NG66	NEK11	S338	S338*	338	Missense	central	0	yes	8.770	0.000	PhosphoSitePlus	GDSC	2.788	Loss
Other_NEK_NEK11_NEK11_ST	P54132	BLM	Q8NG66	NEK11	S462	H457R	457	Missense	distal	-5	no	3.738	3.755	EPSD	GDSC;CCLE	2.788	Up-regulation
Other_NEK_NEK11_NEK11_ST	P54132	BLM	Q8NG66	NEK11	S464	H457R	457	Missense	distal	-7	no	3.943	3.957	EPSD	GDSC;CCLE	2.788	Up-regulation
Other_NEK_NEK11_NEK11_ST	P54132	BLM	Q8NG66	NEK11	S539	E546D	546	Missense	distal	7	no	3.884	3.899	EPSD	GDSC;CCLE	2.788	Up-regulation
Other_NEK_NEK11_NEK11_ST	P54132	BLM	Q8NG66	NEK11	S601	A603V	603	Missense	proximal	2	no	2.848	2.736	EPSD	GDSC;CCLE	2.788	Loss
Other_NEK_NEK11_NEK11_ST	P54132	BLM	Q8NG66	NEK11	S646	S648G	648	Missense	proximal	2	no	3.176	3.288	EPSD	GDSC;CCLE	2.788	Up-regulation
Other_NEK_NEK11_NEK11_ST	P54132	BLM	Q8NG66	NEK11	S646	K653T	653	Missense	distal	7	no	3.176	3.161	EPSD	GDSC	2.788	Down-regulation
TK_Jak_JAK2_Y	P62993	GRB2	O60674	JAK2	Y7	T12A	12	Missense	distal	5	no	6.767	4.477	EPSD;PhosphoSitePlus	GDSC;CCLE	5.995	Loss
TK_Jak_JAK2_Y	P62993	GRB2	O60674	JAK2	Y37	G43V	43	Missense	distal	6	no	8.598	8.342	PhosphoSitePlus;EPSD	GDSC;CCLE	5.995	Down-regulation
TK_Jak_JAK2_Y	O14744	PRMT5	O60674	JAK2	Y297	R291H	291	Missense	distal	-6	no	9.120	8.062	EPSD;PhosphoSitePlus	GDSC;CCLE	5.995	Down-regulation
TK_Jak_JAK2_Y	O14744	PRMT5	O60674	JAK2	Y297	R291C	291	Missense	distal	-6	no	9.120	8.114	EPSD;PhosphoSitePlus	GDSC;CCLE	5.995	Down-regulation
TK_Jak_JAK2_Y	Q9UGK3	STAP2	O60674	JAK2	Y322	P318Q	318	Missense	distal	-4	no	9.562	9.201	EPSD;PhosphoSitePlus	GDSC	5.995	Down-regulation
TK_Jak_JAK2_Y	O60674	JAK2	O60674	JAK2	Y44	Y42H	42	Missense	proximal	-2	no	5.468	8.233	EPSD	GDSC;CCLE	5.995	Gain
TK_Jak_JAK2_Y	O60674	JAK2	O60674	JAK2	Y637	L634P	634	Missense	distal	-3	no	7.231	8.628	EPSD	GDSC;CCLE	5.995	Up-regulation
TK_Jak_JAK2_Y	O60674	JAK2	O60674	JAK2	Y813	P811T	811	Missense	proximal	-2	no	7.455	7.036	EPSD	GDSC;CCLE	5.995	Down-regulation
TK_Jak_JAK2_Y	O60674	JAK2	O60674	JAK2	Y931	Y934N	934	Missense	distal	3	no	7.047	5.314	EPSD	GDSC;CCLE	5.995	Loss
TK_Jak_JAK2_Y	O60674	JAK2	O60674	JAK2	Y934	Y934N	934	Missense	central	0	yes	7.812	0.000	EPSD	GDSC;CCLE	5.995	Loss
TK_Jak_JAK2_Y	O60674	JAK2	O60674	JAK2	Y940	Y934N	934	Missense	distal	-6	no	7.513	7.342	EPSD	GDSC;CCLE	5.995	Down-regulation
TK_Jak_JAK2_Y	P42229	STAT5A	O60674	JAK2	Y694	P697L	697	Missense	distal	3	no	12.625	14.219	PhosphoSitePlus	GDSC	5.995	Up-regulation
TK_Jak_JAK2_Y	P41597	CCR2	O60674	JAK2	Y139	A145V	145	Missense	distal	6	no	9.206	8.927	PhosphoSitePlus	GDSC;CCLE	5.995	Down-regulation
TK_Jak_JAK2_Y	P41597	CCR2	O60674	JAK2	Y139	L133I	133	Missense	distal	-6	no	9.206	8.784	PhosphoSitePlus	GDSC;CCLE	5.995	Down-regulation
TK_Jak_JAK2_Y	P28482	MAPK1	O60674	JAK2	Y187	T185A	185	Missense	proximal	-2	no	12.522	14.463	PhosphoSitePlus	GDSC;CCLE	5.995	Up-regulation
TK_Jak_JAK2_Y	P40763	STAT3	O60674	JAK2	Y705	C712Y	712	Missense	distal	7	no	10.032	10.012	PhosphoSitePlus	GDSC;CCLE	5.995	Down-regulation
TK_Jak_JAK2_Y	Q15118	PDK1	O60674	JAK2	Y49	D47E	47	Missense	proximal	-2	no	7.161	5.696	EPSD	GDSC	5.995	Loss
TK_Jak_JAK2_Y	Q15118	PDK1	O60674	JAK2	Y49	F48L	48	Missense	proximal	-1	no	7.161	7.973	EPSD	GDSC;CCLE	5.995	Up-regulation
TK_Jak_JAK2_Y	Q15118	PDK1	O60674	JAK2	Y243	I245S	245	Missense	proximal	2	no	9.334	9.482	PhosphoSitePlus	GDSC	5.995	Up-regulation
TK_Jak_JAK2_Y	Q15118	PDK1	O60674	JAK2	Y403	A407V	407	Missense	distal	4	no	6.722	6.517	EPSD	GDSC;CCLE	5.995	Down-regulation
TK_Jak_JAK2_Y	P27361	MAPK3	O60674	JAK2	Y204	E203D	203	Missense	proximal	-1	no	13.438	13.299	PhosphoSitePlus	GDSC;CCLE	5.995	Down-regulation
TK_Jak_JAK2_Y	P27361	MAPK3	O60674	JAK2	Y204	H197D	197	Missense	distal	-7	no	13.438	13.379	PhosphoSitePlus	GDSC;CCLE	5.995	Down-regulation
TK_Jak_JAK2_Y	Q9UQC2	GAB2	O60674	JAK2	Y614	V612A	612	Missense	proximal	-2	no	7.068	8.016	EPSD	GDSC;CCLE	5.995	Up-regulation
TK_Jak_JAK2_Y	P42224	STAT1	O60674	JAK2	Y170	L166S	166	Missense	distal	-4	no	6.275	6.486	EPSD	GDSC;CCLE	5.995	Up-regulation
CMGC_CDK_CDK4_CDK4_ST	Q8IZL8	PELP1	P11802	CDK4	T49	A52T	52	Missense	distal	3	no	2.657	2.496	EPSD	GDSC;CCLE	2.642	Loss
CMGC_CDK_CDK4_CDK4_ST	Q8IZL8	PELP1	P11802	CDK4	S804	P808S	808	Missense	distal	4	no	2.648	2.441	EPSD	GDSC	2.642	Loss
CMGC_CDK_CDK4_CDK4_ST	Q8IZL8	PELP1	P11802	CDK4	T807	P808S	808	Missense	proximal	1	no	9.033	2.846	EPSD	GDSC	2.642	Down-regulation
CMGC_CDK_CDK4_CDK4_ST	P06400	RB1	P11802	CDK4	S567	W563*	563	Missense	distal	-4	no	8.961	8.960	EPSD	GDSC	2.642	Down-regulation
CMGC_CDK_CDK4_CDK4_ST	P06400	RB1	P11802	CDK4	S567	S567*	567	Missense	central	0	yes	8.961	0.000	EPSD	GDSC	2.642	Loss
CMGC_CDK_CDK4_CDK4_ST	P06400	RB1	P11802	CDK4	S608	T601S	601	Missense	distal	-7	no	8.292	8.703	EPSD;PhosphoSitePlus	GDSC;CCLE	2.642	Up-regulation
CMGC_CDK_CDK4_CDK4_ST	P06400	RB1	P11802	CDK4	S780	R787*	787	Missense	distal	7	no	8.334	8.328	PhosphoSitePlus;EPSD	GDSC	2.642	Down-regulation
CMGC_CDK_CDK4_CDK4_ST	P06400	RB1	P11802	CDK4	S788	R787*	787	Missense	proximal	-1	no	9.839	9.975	EPSD;PhosphoSitePlus	GDSC	2.642	Up-regulation
CMGC_CDK_CDK4_CDK4_ST	P06400	RB1	P11802	CDK4	S795	G801*	801	Missense	distal	6	no	8.275	8.393	EPSD;PhosphoSitePlus	GDSC	2.642	Up-regulation
CMGC_CDK_CDK4_CDK4_ST	P06400	RB1	P11802	CDK4	S807	G801*	801	Missense	distal	-6	no	8.321	8.064	EPSD;PhosphoSitePlus	GDSC	2.642	Down-regulation
CMGC_CDK_CDK4_CDK4_ST	P06400	RB1	P11802	CDK4	T821	L819V	819	Missense	proximal	-2	no	6.539	6.541	EPSD	GDSC;CCLE	2.642	Up-regulation
CMGC_CDK_CDK4_CDK4_ST	P06400	RB1	P11802	CDK4	T826	L819V	819	Missense	distal	-7	no	9.039	9.017	EPSD;PhosphoSitePlus	GDSC;CCLE	2.642	Down-regulation
CMGC_CDK_CDK4_CDK4_ST	Q08999	RBL2	P11802	CDK4	T417	T423M	423	Missense	distal	6	no	7.203	7.138	EPSD	GDSC;CCLE	2.642	Down-regulation
CMGC_CDK_CDK4_CDK4_ST	Q08999	RBL2	P11802	CDK4	S1035	M1029I	1029	Missense	distal	-6	no	8.592	8.639	EPSD;PhosphoSitePlus	GDSC	2.642	Up-regulation
CMGC_CDK_CDK4_CDK4_ST	Q08999	RBL2	P11802	CDK4	T1042	S1035T	1035	Missense	distal	-7	no	2.898	2.487	EPSD	GDSC;CCLE	2.642	Loss
CMGC_CDK_CDK4_CDK4_ST	Q08999	RBL2	P11802	CDK4	S1068	R1070*	1070	Missense	proximal	2	no	6.398	6.274	EPSD	GDSC	2.642	Down-regulation
CMGC_CDK_CDK4_CDK4_ST	Q08999	RBL2	P11802	CDK4	S1112	P1119A	1119	Missense	distal	7	no	8.786	8.785	EPSD	GDSC;CCLE	2.642	Down-regulation
CMGC_CDK_CDK4_CDK4_ST	P30304	CDC25A	P11802	CDK4	S76	G75C	75	Missense	proximal	-1	no	3.342	3.166	EPSD	GDSC;CCLE	2.642	Down-regulation
CMGC_CDK_CDK4_CDK4_ST	P30304	CDC25A	P11802	CDK4	S283	S287N	287	Missense	distal	4	no	7.257	7.483	EPSD	GDSC	2.642	Up-regulation
CMGC_CDK_CDK4_CDK4_ST	P30304	CDC25A	P11802	CDK4	S321	A319V	319	Missense	proximal	-2	no	6.140	6.012	EPSD	GDSC;CCLE	2.642	Down-regulation
CMGC_CDK_CDK4_CDK4_ST	P30304	CDC25A	P11802	CDK4	S321	Q314*	314	Missense	distal	-7	no	6.140	6.132	EPSD	GDSC	2.642	Down-regulation
CMGC_CDK_CDK4_CDK4_ST	Q12778	FOXO1	P11802	CDK4	S218	L219P	219	Missense	proximal	1	no	1.267	8.846	EPSD	GDSC;CCLE	2.642	Gain
CMGC_CDK_CDK4_CDK4_ST	Q12778	FOXO1	P11802	CDK4	S329	T333A	333	Missense	distal	4	no	8.621	8.486	EPSD	GDSC;CCLE	2.642	Down-regulation
CMGC_CDK_CDK4_CDK4_ST	Q12778	FOXO1	P11802	CDK4	S383	L381F	381	Missense	proximal	-2	no	7.429	7.527	EPSD	GDSC	2.642	Up-regulation
CMGC_CDK_CDK4_CDK4_ST	P84022	SMAD3	P11802	CDK4	T179	P172T	172	Missense	distal	-7	no	8.331	8.121	EPSD;PhosphoSitePlus	GDSC;CCLE	2.642	Down-regulation
CMGC_CDK_CDK4_CDK4_ST	P26358	DNMT1	P11802	CDK4	S127	N126H	126	Missense	proximal	-1	no	7.446	7.540	PhosphoSitePlus;EPSD	GDSC;CCLE	2.642	Up-regulation
CMGC_CDK_CDK4_CDK4_ST	Q14814	MEF2D	P11802	CDK4	S98	K91Q	91	Missense	distal	-7	no	8.576	8.459	PhosphoSitePlus;EPSD	GDSC	2.642	Down-regulation
CMGC_CDK_CDK4_CDK4_ST	Q14814	MEF2D	P11802	CDK4	S98	K91N	91	Missense	distal	-7	no	8.576	8.537	PhosphoSitePlus;EPSD	GDSC	2.642	Down-regulation
CMGC_CDK_CDK4_CDK4_ST	Q14814	MEF2D	P11802	CDK4	S98	G95C	95	Missense	distal	-3	no	8.576	8.527	PhosphoSitePlus;EPSD	GDSC;CCLE	2.642	Down-regulation
CMGC_CDK_CDK4_CDK4_ST	Q14814	MEF2D	P11802	CDK4	S110	Q109K	109	Missense	proximal	-1	no	7.937	7.787	EPSD;PhosphoSitePlus	GDSC	2.642	Down-regulation
CMGC_CDK_CDK4_CDK4_ST	Q14814	MEF2D	P11802	CDK4	S251	P254L	254	Missense	distal	3	no	8.081	7.183	EPSD	GDSC;CCLE	2.642	Down-regulation
CMGC_CDK_CDK4_CDK4_ST	Q14814	MEF2D	P11802	CDK4	S258	T259P	259	Missense	proximal	1	no	1.147	7.674	EPSD	GDSC	2.642	Gain
CMGC_CDK_CDK4_CDK4_ST	Q14814	MEF2D	P11802	CDK4	S444	R449H	449	Missense	distal	5	no	10.359	10.369	EPSD	GDSC;CCLE	2.642	Up-regulation
CMGC_CDK_CDK4_CDK4_ST	Q14814	MEF2D	P11802	CDK4	S444	S444P	444	Missense	central	0	yes	10.359	0.000	EPSD	GDSC	2.642	Loss
CMGC_CDK_CDK4_CDK4_ST	Q14814	MEF2D	P11802	CDK4	S444	P445Q	445	Missense	proximal	1	no	10.359	3.190	EPSD	GDSC	2.642	Down-regulation
CMGC_CDK_CDK4_CDK4_ST	Q14814	MEF2D	P11802	CDK4	S450	R449H	449	Missense	proximal	-1	no	7.572	7.721	EPSD	GDSC;CCLE	2.642	Up-regulation
CMGC_CDK_CDK4_CDK4_ST	Q14814	MEF2D	P11802	CDK4	S450	S444P	444	Missense	distal	-6	no	7.572	7.782	EPSD	GDSC	2.642	Up-regulation
CMGC_CDK_CDK4_CDK4_ST	Q14814	MEF2D	P11802	CDK4	S450	P445Q	445	Missense	distal	-5	no	7.572	7.596	EPSD	GDSC	2.642	Up-regulation
CMGC_CDK_CDK4_CDK4_ST	Q14814	MEF2D	P11802	CDK4	S472	G475R	475	Missense	distal	3	no	8.018	8.580	EPSD	GDSC	2.642	Up-regulation
CMGC_CDK_CDK4_CDK4_ST	P38398	BRCA1	P11802	CDK4	S896	Q895*	895	Missense	proximal	-1	no	7.792	7.823	EPSD	GDSC	2.642	Up-regulation
CMGC_CDK_CDK4_CDK4_ST	P38398	BRCA1	P11802	CDK4	S1480	A1481V	1481	Missense	proximal	1	no	3.236	2.845	EPSD	GDSC;CCLE	2.642	Down-regulation
CMGC_CDK_CDK4_CDK4_ST	P38398	BRCA1	P11802	CDK4	S1514	Q1518H	1518	Missense	distal	4	no	2.872	2.924	EPSD	GDSC	2.642	Up-regulation
CMGC_CDK_CDK4_CDK4_ST	Q96KS0	EGLN2	P11802	CDK4	S74	T72N	72	Missense	proximal	-2	no	7.682	7.670	EPSD	GDSC;CCLE	2.642	Down-regulation
CMGC_CDK_CDK4_CDK4_ST	Q96KS0	EGLN2	P11802	CDK4	S130	E123K	123	Missense	distal	-7	no	6.672	6.627	PhosphoSitePlus	GDSC	2.642	Down-regulation
CMGC_CDK_CDK4_CDK4_ST	P15923	TCF3	P11802	CDK4	S391	D395N	395	Missense	distal	4	no	2.909	2.743	EPSD	GDSC;CCLE	2.642	Down-regulation
CMGC_CDK_CDK4_CDK4_ST	P15923	TCF3	P11802	CDK4	T508	T508M	508	Missense	central	0	yes	2.885	0.000	EPSD	GDSC	2.642	Loss
CMGC_CDK_CDK4_CDK4_ST	P15923	TCF3	P11802	CDK4	S529	K522Q	522	Missense	distal	-7	no	8.297	8.180	EPSD	GDSC	2.642	Down-regulation
CMGC_CDK_CDK4_CDK4_ST	P15923	TCF3	P11802	CDK4	S529	P524L	524	Missense	distal	-5	no	8.297	8.282	EPSD	GDSC;CCLE	2.642	Down-regulation
CMGC_CDK_CDK4_CDK4_ST	Q9BQA1	WDR77	P11802	CDK4	S264	V262L	262	Missense	proximal	-2	no	9.198	9.197	PhosphoSitePlus;EPSD	GDSC;CCLE	2.642	Down-regulation
CMGC_CDK_CDK4_CDK4_ST	Q9BQA1	WDR77	P11802	CDK4	S264	L271P	271	Missense	distal	7	no	9.198	9.215	PhosphoSitePlus;EPSD	GDSC	2.642	Up-regulation
CMGC_CDK_CDK4_CDK4_ST	Q9BQA1	WDR77	P11802	CDK4	S306	H310Q	310	Missense	distal	4	no	8.018	7.965	EPSD;PhosphoSitePlus	GDSC;CCLE	2.642	Down-regulation
CMGC_CDK_CDK4_CDK4_ST	P46527	CDKN1B	P11802	CDK4	S178	G177S	177	Missense	proximal	-1	no	7.626	7.110	EPSD	GDSC;CCLE	2.642	Down-regulation
CMGC_CDK_CDK4_CDK4_ST	P21333	FLNA	P11802	CDK4	S204	A206V	206	Missense	proximal	2	no	2.917	2.740	EPSD	GDSC;CCLE	2.642	Down-regulation
CMGC_CDK_CDK4_CDK4_ST	P21333	FLNA	P11802	CDK4	S468	G475V	475	Missense	distal	7	no	8.346	8.355	EPSD	GDSC;CCLE	2.642	Up-regulation
CMGC_CDK_CDK4_CDK4_ST	P21333	FLNA	P11802	CDK4	S512	Y506C	506	Missense	distal	-6	no	2.809	2.888	EPSD	GDSC;CCLE	2.642	Up-regulation
CMGC_CDK_CDK4_CDK4_ST	P21333	FLNA	P11802	CDK4	T938	N931D	931	Missense	distal	-7	no	6.102	5.956	EPSD	GDSC;CCLE	2.642	Down-regulation
CMGC_CDK_CDK4_CDK4_ST	P21333	FLNA	P11802	CDK4	S1533	K1538N	1538	Missense	distal	5	no	8.319	8.324	EPSD	GDSC;CCLE	2.642	Up-regulation
CMGC_CDK_CDK4_CDK4_ST	P21333	FLNA	P11802	CDK4	S1630	R1633P	1633	Missense	distal	3	no	8.722	9.269	EPSD	GDSC;CCLE	2.642	Up-regulation
CMGC_CDK_CDK4_CDK4_ST	P21333	FLNA	P11802	CDK4	S1906	E1903K	1903	Missense	distal	-3	no	3.069	3.039	EPSD	GDSC	2.642	Down-regulation
CMGC_CDK_CDK4_CDK4_ST	P21333	FLNA	P11802	CDK4	S1906	A1908V	1908	Missense	proximal	2	no	3.069	2.892	EPSD	GDSC	2.642	Down-regulation
CMGC_CDK_CDK4_CDK4_ST	P21333	FLNA	P11802	CDK4	S2224	Q2219R	2219	Missense	distal	-5	no	9.496	9.500	EPSD	GDSC;CCLE	2.642	Up-regulation
CMGC_CDK_CDK4_CDK4_ST	P21333	FLNA	P11802	CDK4	S2319	N2312D	2312	Missense	distal	-7	no	8.717	8.570	EPSD	GDSC;CCLE	2.642	Down-regulation
CMGC_CDK_CDK4_CDK4_ST	P21333	FLNA	P11802	CDK4	S2319	N2312K	2312	Missense	distal	-7	no	8.717	8.756	EPSD	GDSC;CCLE	2.642	Up-regulation
CMGC_CDK_CDK4_CDK4_ST	P21333	FLNA	P11802	CDK4	S2327	R2334C	2334	Missense	distal	7	no	6.517	6.506	EPSD	GDSC	2.642	Down-regulation
CMGC_CDK_CDK4_CDK4_ST	P21333	FLNA	P11802	CDK4	S2343	P2350A	2350	Missense	distal	7	no	3.429	3.428	EPSD	GDSC;CCLE	2.642	Down-regulation
CMGC_CDK_CDK4_CDK4_ST	P21333	FLNA	P11802	CDK4	S2352	P2350A	2350	Missense	proximal	-2	no	3.806	3.406	EPSD	GDSC;CCLE	2.642	Down-regulation
CMGC_CDK_CDK4_CDK4_ST	P21333	FLNA	P11802	CDK4	S2640	P2638Q	2638	Missense	proximal	-2	no	8.982	8.502	EPSD	GDSC;CCLE	2.642	Down-regulation
CMGC_CDK_CDK4_CDK4_ST	P04179	SOD2	P11802	CDK4	S106	E112G	112	Missense	distal	6	no	7.812	7.646	PhosphoSitePlus	GDSC	2.642	Down-regulation
CMGC_CDK_CDK4_CDK4_ST	Q92879	CELF1	P11802	CDK4	S296	S297P	297	Missense	proximal	1	no	2.102	8.289	EPSD	GDSC;CCLE	2.642	Gain
CMGC_CDK_CDK4_CDK4_ST	Q92879	CELF1	P11802	CDK4	S297	S297P	297	Missense	central	0	yes	3.097	0.000	EPSD	GDSC;CCLE	2.642	Loss
CMGC_CDK_CDK4_CDK4_ST	Q92879	CELF1	P11802	CDK4	S299	S297P	297	Missense	proximal	-2	no	2.705	3.010	EPSD	GDSC;CCLE	2.642	Up-regulation
CMGC_CDK_CDK4_CDK4_ST	Q92879	CELF1	P11802	CDK4	S300	S297P	297	Missense	distal	-3	no	6.987	6.912	EPSD	GDSC;CCLE	2.642	Down-regulation
CMGC_CDK_CDK4_CDK4_ST	Q92879	CELF1	P11802	CDK4	S302	S297P	297	Missense	distal	-5	no	4.128	3.992	PhosphoSitePlus	GDSC;CCLE	2.642	Down-regulation
CMGC_CDK_CDK4_CDK4_ST	P04637	TP53	P11802	CDK4	S33	Q38*	38	Missense	distal	5	no	7.064	7.063	EPSD	GDSC	2.642	Down-regulation
CMGC_CDK_CDK4_CDK4_ST	P04637	TP53	P11802	CDK4	T81	A74S	74	Missense	distal	-7	no	8.060	8.276	EPSD	GDSC;CCLE	2.642	Up-regulation
CMGC_CDK_CDK4_CDK4_ST	P04637	TP53	P11802	CDK4	S99	Q100*	100	Missense	proximal	1	no	2.211	3.001	EPSD	GDSC	2.642	Gain
CMGC_CDK_CDK4_CDK4_ST	P04637	TP53	P11802	CDK4	S127	Y126*	126	Missense	proximal	-1	no	7.138	7.172	EPSD	GDSC	2.642	Up-regulation
CMGC_CDK_CDK4_CDK4_ST	P04637	TP53	P11802	CDK4	S127	K120*	120	Missense	distal	-7	no	7.138	7.013	EPSD	GDSC	2.642	Down-regulation
CMGC_CDK_CDK4_CDK4_ST	P04637	TP53	P11802	CDK4	T150	Q144*	144	Missense	distal	-6	no	7.199	7.214	EPSD	GDSC	2.642	Up-regulation
CMGC_CDK_CDK4_CDK4_ST	P04637	TP53	P11802	CDK4	S315	Q317*	317	Missense	proximal	2	no	8.449	8.433	EPSD	GDSC	2.642	Down-regulation
CMGC_CDK_CDK4_CDK4_ST	P04637	TP53	P11802	CDK4	S315	K319*	319	Missense	distal	4	no	8.449	8.591	EPSD	GDSC	2.642	Up-regulation
CMGC_CDK_CDK4_CDK4_ST	P28749	RBL1	P11802	CDK4	S629	R626*	626	Missense	distal	-3	no	3.690	3.721	EPSD	GDSC	2.642	Up-regulation
CMGC_CDK_CDK4_CDK4_ST	P28749	RBL1	P11802	CDK4	S762	T769I	769	Missense	distal	7	no	6.469	6.459	EPSD	GDSC;CCLE	2.642	Down-regulation
CMGC_CDK_CDK4_CDK4_ST	P28749	RBL1	P11802	CDK4	S762	S757*	757	Missense	distal	-5	no	6.469	6.351	EPSD	GDSC	2.642	Down-regulation
CMGC_CDK_CDK4_CDK4_ST	P28749	RBL1	P11802	CDK4	T915	S919F	919	Missense	distal	4	no	6.714	7.112	EPSD	GDSC;CCLE	2.642	Up-regulation
CMGC_CDK_CDK4_CDK4_ST	P28749	RBL1	P11802	CDK4	S975	P973T	973	Missense	proximal	-2	no	7.914	7.492	EPSD;PhosphoSitePlus	GDSC;CCLE	2.642	Down-regulation
CMGC_CDK_CDK4_CDK4_ST	P28749	RBL1	P11802	CDK4	T997	L1003P	1003	Missense	distal	6	no	6.149	6.171	EPSD	GDSC;CCLE	2.642	Up-regulation
CMGC_CDK_CDK4_CDK4_ST	P28749	RBL1	P11802	CDK4	S1009	L1003P	1003	Missense	distal	-6	no	7.843	7.690	EPSD	GDSC;CCLE	2.642	Down-regulation
CMGC_CDK_CDK4_CDK4_ST	P43694	GATA4	P11802	CDK4	S406	P407Q	407	Missense	proximal	1	no	8.771	1.601	EPSD	GDSC	2.642	Loss
CMGC_CDK_CDK4_CDK4_ST	P43694	GATA4	P11802	CDK4	S412	P407Q	407	Missense	distal	-5	no	6.893	6.917	EPSD	GDSC	2.642	Up-regulation
CMGC_CDK_CDK4_CDK4_ST	O43791	SPOP	P11802	CDK4	S6	A11V	11	Missense	distal	5	no	8.610	8.637	PhosphoSitePlus	GDSC;CCLE	2.642	Up-regulation
STE_STE11_MEKK2_MAP3K3_ST	P08151	GLI1	Q99759	MAP3K3	S89	P87S	87	Missense	proximal	-2	no	11.297	10.147	EPSD	GDSC;CCLE	11.002	Loss
STE_STE11_MEKK2_MAP3K3_ST	P08151	GLI1	Q99759	MAP3K3	S968	P969A	969	Missense	proximal	1	no	28.505	26.657	EPSD;PhosphoSitePlus	GDSC;CCLE	11.002	Down-regulation
STE_STE11_MEKK2_MAP3K3_ST	P08151	GLI1	Q99759	MAP3K3	S968	F974V	974	Missense	distal	6	no	28.505	28.207	EPSD;PhosphoSitePlus	GDSC;CCLE	11.002	Down-regulation
STE_STE11_MEKK2_MAP3K3_ST	P53805	RCAN1	Q99759	MAP3K3	S163	S163C	163	Missense	central	0	yes	28.012	0.000	PhosphoSitePlus;EPSD	GDSC;CCLE	11.002	Loss
STE_STE11_MEKK2_MAP3K3_ST	P53805	RCAN1	Q99759	MAP3K3	S167	S163C	163	Missense	distal	-4	no	29.082	24.686	EPSD;PhosphoSitePlus	GDSC;CCLE	11.002	Down-regulation
STE_STE11_MEKK2_MAP3K3_ST	P53805	RCAN1	Q99759	MAP3K3	T247	T241S	241	Missense	distal	-6	no	12.331	12.968	EPSD	GDSC;CCLE	11.002	Up-regulation
TKL_STKR_STKR1_TGFBR1_ST	Q03167	TGFBR3	P36897	TGFBR1	S651	P647S	647	Missense	distal	-4	no	14.135	13.266	EPSD	GDSC;CCLE	13.873	Loss
TKL_STKR_STKR1_TGFBR1_ST	Q03167	TGFBR3	P36897	TGFBR1	S651	Y653H	653	Missense	proximal	2	no	14.135	14.140	EPSD	GDSC;CCLE	13.873	Up-regulation
TKL_STKR_STKR1_TGFBR1_ST	Q15796	SMAD2	P36897	TGFBR1	S464	S464*	464	Missense	central	0	yes	17.945	0.000	EPSD;PhosphoSitePlus	GDSC	13.873	Loss
TKL_STKR_STKR1_TGFBR1_ST	Q15796	SMAD2	P36897	TGFBR1	S465	S464*	464	Missense	proximal	-1	no	17.513	22.021	PhosphoSitePlus;EPSD	GDSC	13.873	Up-regulation
TKL_STKR_STKR1_TGFBR1_ST	Q15796	SMAD2	P36897	TGFBR1	S467	S464*	464	Missense	distal	-3	no	19.526	18.370	EPSD;PhosphoSitePlus	GDSC	13.873	Down-regulation
TKL_STKR_STKR1_TGFBR1_ST	Q9H3D4	TP63	P36897	TGFBR1	S68	E63*	63	Missense	distal	-5	no	13.136	14.153	PhosphoSitePlus	GDSC	13.873	Gain
TKL_STKR_STKR1_TGFBR1_ST	Q9H3D4	TP63	P36897	TGFBR1	S160	T155I	155	Missense	distal	-5	no	29.350	30.451	EPSD	GDSC;CCLE	13.873	Up-regulation
TKL_STKR_STKR1_TGFBR1_ST	Q9H3D4	TP63	P36897	TGFBR1	S162	T155I	155	Missense	distal	-7	no	28.456	27.549	EPSD	GDSC;CCLE	13.873	Down-regulation
TKL_STKR_STKR1_TGFBR1_ST	Q9H3D4	TP63	P36897	TGFBR1	S455	S457P	457	Missense	proximal	2	no	14.980	14.607	EPSD	GDSC	13.873	Down-regulation
TKL_STKR_STKR1_TGFBR1_ST	Q9H3D4	TP63	P36897	TGFBR1	S457	S457P	457	Missense	central	0	yes	15.283	0.000	EPSD	GDSC	13.873	Loss
TKL_STKR_STKR1_TGFBR1_ST	Q9H3D4	TP63	P36897	TGFBR1	S463	S457P	457	Missense	distal	-6	no	17.273	17.900	EPSD	GDSC	13.873	Up-regulation
CAMK_MAPKAPK_MK5_MAPKAPK5_ST	O60229	KALRN	Q8IW41	MAPKAPK5	S487	R484W	484	Missense	distal	-3	no	48.952	35.526	PhosphoSitePlus	GDSC;CCLE	23.028	Down-regulation
CAMK_MAPKAPK_MK5_MAPKAPK5_ST	P25685	DNAJB1	Q8IW41	MAPKAPK5	S16	A15V	15	Missense	proximal	-1	no	31.100	41.598	EPSD	GDSC;CCLE	23.028	Up-regulation
CAMK_MAPKAPK_MK5_MAPKAPK5_ST	P25685	DNAJB1	Q8IW41	MAPKAPK5	S16	A23V	23	Missense	distal	7	no	31.100	31.262	EPSD	GDSC;CCLE	23.028	Up-regulation
CAMK_MAPKAPK_MK5_MAPKAPK5_ST	P25685	DNAJB1	Q8IW41	MAPKAPK5	S149	G147D	147	Missense	proximal	-2	no	41.858	41.968	EPSD;PhosphoSitePlus	GDSC;CCLE	23.028	Up-regulation
CAMK_MAPKAPK_MK5_MAPKAPK5_ST	P25685	DNAJB1	Q8IW41	MAPKAPK5	S151	G147D	147	Missense	distal	-4	no	43.868	44.241	EPSD;PhosphoSitePlus	GDSC;CCLE	23.028	Up-regulation
CAMK_MAPKAPK_MK5_MAPKAPK5_ST	P04637	TP53	Q8IW41	MAPKAPK5	S37	Q38*	38	Missense	proximal	1	no	42.124	42.220	PhosphoSitePlus	GDSC	23.028	Up-regulation
CAMK_MAPKAPK_MK5_MAPKAPK5_ST	P04637	TP53	Q8IW41	MAPKAPK5	S127	K120*	120	Missense	distal	-7	no	22.875	23.499	EPSD	GDSC	23.028	Gain
CAMK_MAPKAPK_MK5_MAPKAPK5_ST	P04637	TP53	Q8IW41	MAPKAPK5	S362	G360V	360	Missense	proximal	-2	no	29.531	29.545	EPSD	GDSC;CCLE	23.028	Up-regulation
CAMK_MAPKAPK_MK5_MAPKAPK5_ST	P04637	TP53	Q8IW41	MAPKAPK5	S366	G360V	360	Missense	distal	-6	no	31.733	31.952	EPSD	GDSC;CCLE	23.028	Up-regulation
CAMK_MAPKAPK_MK5_MAPKAPK5_ST	Q15382	RHEB	Q8IW41	MAPKAPK5	S130	H124Y	124	Missense	distal	-6	no	43.637	43.853	PhosphoSitePlus	GDSC	23.028	Up-regulation
CAMK_DAPK_DAPK_DAPK2_ST	Q9UIK4	DAPK2	Q9UIK4	DAPK2	S367	T369N	369	Missense	proximal	2	no	3.511	3.550	EPSD	GDSC;CCLE	1.958	Up-regulation
CAMK_DAPK_DAPK_DAPK2_ST	Q9UIK4	DAPK2	Q9UIK4	DAPK2	T369	T369N	369	Missense	central	0	yes	2.002	0.000	EPSD	GDSC;CCLE	1.958	Loss
CAMK_DAPK_DAPK_DAPK2_ST	Q8N122	RPTOR	Q9UIK4	DAPK2	T700	L694F	694	Missense	distal	-6	no	2.705	2.721	EPSD	GDSC;CCLE	1.958	Up-regulation
CAMK_DAPK_DAPK_DAPK2_ST	Q8N122	RPTOR	Q9UIK4	DAPK2	S721	R716I	716	Missense	distal	-5	no	2.232	0.880	PhosphoSitePlus	GDSC;CCLE	1.958	Loss
CAMK_DAPK_DAPK_DAPK2_ST	Q8N122	RPTOR	Q9UIK4	DAPK2	S721	R718H	718	Missense	distal	-3	no	2.232	1.535	PhosphoSitePlus	GDSC;CCLE	1.958	Loss
CAMK_DAPK_DAPK_DAPK2_ST	Q8N122	RPTOR	Q9UIK4	DAPK2	T731	S734N	734	Missense	distal	3	no	2.877	2.771	EPSD	GDSC;CCLE	1.958	Down-regulation
CAMK_DAPK_DAPK_DAPK2_ST	Q8N122	RPTOR	Q9UIK4	DAPK2	S794	S798P	798	Missense	distal	4	no	3.213	3.212	EPSD	GDSC	1.958	Down-regulation
AGC_PKC_PKCh_PRKCH_ST	Q06124	PTPN11	P24723	PRKCH	S580	V583M	583	Missense	distal	3	no	33.107	33.067	EPSD	GDSC;CCLE	22.099	Down-regulation
AGC_PKC_PKCh_PRKCH_ST	P49841	GSK3B	P24723	PRKCH	S2	T8P	8	Missense	distal	6	no	20.577	22.438	EPSD	GDSC	22.099	Gain
AGC_PKC_PKCh_PRKCH_ST	P49841	GSK3B	P24723	PRKCH	T8	T8P	8	Missense	central	0	yes	24.307	0.000	EPSD	GDSC	22.099	Loss
AGC_PKC_PKCh_PRKCH_ST	P49841	GSK3B	P24723	PRKCH	S9	T8P	8	Missense	proximal	-1	no	43.547	43.116	PhosphoSitePlus	GDSC	22.099	Down-regulation
AGC_PKC_PKCh_PRKCH_ST	P49841	GSK3B	P24723	PRKCH	S21	S21L	21	Missense	central	0	yes	23.547	0.000	EPSD	GDSC;CCLE	22.099	Loss
AGC_PKC_PKCh_PRKCH_ST	Q15139	PRKD1	P24723	PRKCH	S379	D384E	384	Missense	distal	5	no	23.225	22.049	EPSD	GDSC;CCLE	22.099	Loss
AGC_PKC_PKCh_PRKCH_ST	Q9BZL6	PRKD2	P24723	PRKCH	T276	C281Y	281	Missense	distal	5	no	22.532	20.261	EPSD	GDSC;CCLE	22.099	Loss
AGC_PKC_PKCh_PRKCH_ST	Q9BZL6	PRKD2	P24723	PRKCH	T397	R400Q	400	Missense	distal	3	no	25.216	25.465	EPSD	GDSC;CCLE	22.099	Up-regulation
AGC_PKC_PKCh_PRKCH_ST	Q9BZL6	PRKD2	P24723	PRKCH	T433	T433M	433	Missense	central	0	yes	22.862	0.000	EPSD	GDSC;CCLE	22.099	Loss
AGC_PKC_PKCh_PRKCH_ST	Q9BZL6	PRKD2	P24723	PRKCH	S706	R708C	708	Missense	proximal	2	no	43.845	41.116	EPSD;PhosphoSitePlus	GDSC;CCLE	22.099	Down-regulation
AGC_PKC_PKCh_PRKCH_ST	Q9BZL6	PRKD2	P24723	PRKCH	S710	R708C	708	Missense	proximal	-2	no	43.969	36.513	EPSD;PhosphoSitePlus	GDSC;CCLE	22.099	Down-regulation
AGC_PKC_PKCh_PRKCH_ST	P09211	GSTP1	P24723	PRKCH	S43	W39*	39	Missense	distal	-4	no	41.730	41.751	EPSD;PhosphoSitePlus	GDSC	22.099	Up-regulation
Other_PLK_PLK1_PLK1_ST	O60563	CCNT1	P53350	PLK1	S22	Q18L	18	Missense	distal	-4	no	12.291	12.376	EPSD	GDSC;CCLE	10.919	Up-regulation
Other_PLK_PLK1_PLK1_ST	O60563	CCNT1	P53350	PLK1	T278	E276*	276	Missense	proximal	-2	no	11.485	3.537	EPSD	GDSC	10.919	Loss
Other_PLK_PLK1_PLK1_ST	O60563	CCNT1	P53350	PLK1	T282	E276*	276	Missense	distal	-6	no	11.337	10.112	EPSD	GDSC	10.919	Loss
Other_PLK_PLK1_PLK1_ST	P60484	PTEN	P53350	PLK1	S338	R335*	335	Missense	distal	-3	no	10.952	10.674	EPSD	GDSC	10.919	Loss
Other_PLK_PLK1_PLK1_ST	P30305	CDC25B	P53350	PLK1	T127	A124S	124	Missense	distal	-3	no	13.080	12.558	PhosphoSitePlus;EPSD	GDSC;CCLE	10.919	Down-regulation
Other_PLK_PLK1_PLK1_ST	P30305	CDC25B	P53350	PLK1	S397	Y396*	396	Missense	proximal	-1	no	13.968	10.400	EPSD;PhosphoSitePlus	GDSC	10.919	Loss
Other_PLK_PLK1_PLK1_ST	P30305	CDC25B	P53350	PLK1	S465	R461S	461	Missense	distal	-4	no	12.264	12.830	EPSD;PhosphoSitePlus	GDSC;CCLE	10.919	Up-regulation
Other_PLK_PLK1_PLK1_ST	P30305	CDC25B	P53350	PLK1	S513	N509S	509	Missense	distal	-4	no	11.334	11.469	EPSD;PhosphoSitePlus	GDSC;CCLE	10.919	Up-regulation
Other_PLK_PLK1_PLK1_ST	P30305	CDC25B	P53350	PLK1	S513	Y511H	511	Missense	proximal	-2	no	11.334	9.689	EPSD;PhosphoSitePlus	GDSC	10.919	Loss
Other_PLK_PLK1_PLK1_ST	P33981	TTK	P53350	PLK1	S37	S37R	37	Missense	central	0	yes	12.888	0.000	EPSD;PhosphoSitePlus	GDSC;CCLE	10.919	Loss
Other_PLK_PLK1_PLK1_ST	P33981	TTK	P53350	PLK1	S37	K40N	40	Missense	distal	3	no	12.888	12.960	EPSD;PhosphoSitePlus	GDSC;CCLE	10.919	Up-regulation
Other_PLK_PLK1_PLK1_ST	P33981	TTK	P53350	PLK1	S353	L356V	356	Missense	distal	3	no	11.291	11.589	EPSD	GDSC	10.919	Up-regulation
Other_PLK_PLK1_PLK1_ST	P33981	TTK	P53350	PLK1	S363	L356V	356	Missense	distal	-7	no	14.324	14.332	EPSD;PhosphoSitePlus	GDSC	10.919	Up-regulation
Other_PLK_PLK1_PLK1_ST	P33981	TTK	P53350	PLK1	S742	Q736R	736	Missense	distal	-6	no	12.461	12.014	EPSD	GDSC;CCLE	10.919	Down-regulation
Other_PLK_PLK1_PLK1_ST	Q9H1A4	ANAPC1	P53350	PLK1	S298	T291P	291	Missense	distal	-7	no	11.651	11.449	EPSD	GDSC;CCLE	10.919	Down-regulation
Other_PLK_PLK1_PLK1_ST	Q9H1A4	ANAPC1	P53350	PLK1	S298	T297A	297	Missense	proximal	-1	no	11.651	11.931	EPSD	GDSC;CCLE	10.919	Up-regulation
Other_PLK_PLK1_PLK1_ST	Q9H1A4	ANAPC1	P53350	PLK1	S351	R352C	352	Missense	proximal	1	no	10.172	11.572	EPSD	GDSC	10.919	Gain
Other_PLK_PLK1_PLK1_ST	Q9H1A4	ANAPC1	P53350	PLK1	S355	R352C	352	Missense	distal	-3	no	12.258	11.462	EPSD;PhosphoSitePlus	GDSC	10.919	Down-regulation
Other_PLK_PLK1_PLK1_ST	Q9H1A4	ANAPC1	P53350	PLK1	S355	S351C	351	Missense	distal	-4	no	12.258	11.446	EPSD;PhosphoSitePlus	GDSC	10.919	Down-regulation
Other_PLK_PLK1_PLK1_ST	Q9H1A4	ANAPC1	P53350	PLK1	S355	V360L	360	Missense	distal	5	no	12.258	12.083	EPSD;PhosphoSitePlus	GDSC;CCLE	10.919	Down-regulation
Other_PLK_PLK1_PLK1_ST	Q9H1A4	ANAPC1	P53350	PLK1	T524	T524A	524	Missense	central	0	yes	11.557	0.000	EPSD	GDSC	10.919	Loss
Other_PLK_PLK1_PLK1_ST	Q9H1A4	ANAPC1	P53350	PLK1	T524	T520R	520	Missense	distal	-4	no	11.557	11.353	EPSD	GDSC	10.919	Down-regulation
Other_PLK_PLK1_PLK1_ST	Q9H1A4	ANAPC1	P53350	PLK1	T530	T524A	524	Missense	distal	-6	no	12.042	12.109	EPSD;PhosphoSitePlus	GDSC	10.919	Up-regulation
Other_PLK_PLK1_PLK1_ST	Q9H1A4	ANAPC1	P53350	PLK1	T530	V535D	535	Missense	distal	5	no	12.042	12.363	EPSD;PhosphoSitePlus	GDSC;CCLE	10.919	Up-regulation
Other_PLK_PLK1_PLK1_ST	Q9H1A4	ANAPC1	P53350	PLK1	S547	L541V	541	Missense	distal	-6	no	10.928	10.988	EPSD;PhosphoSitePlus	GDSC;CCLE	10.919	Up-regulation
Other_PLK_PLK1_PLK1_ST	Q9H1A4	ANAPC1	P53350	PLK1	S686	N680S	680	Missense	distal	-6	no	12.056	12.253	EPSD	GDSC	10.919	Up-regulation
Other_PLK_PLK1_PLK1_ST	Q9H1A4	ANAPC1	P53350	PLK1	S892	R898G	898	Missense	distal	6	no	12.506	12.609	EPSD	GDSC;CCLE	10.919	Up-regulation
Other_PLK_PLK1_PLK1_ST	Q9H1A4	ANAPC1	P53350	PLK1	S893	R898G	898	Missense	distal	5	no	11.126	10.964	EPSD	GDSC;CCLE	10.919	Down-regulation
Other_PLK_PLK1_PLK1_ST	P35568	IRS1	P53350	PLK1	S372	H371R	371	Missense	proximal	-1	no	14.136	13.138	EPSD	GDSC	10.919	Down-regulation
Other_PLK_PLK1_PLK1_ST	P35568	IRS1	P53350	PLK1	S372	P368A	368	Missense	distal	-4	no	14.136	14.297	EPSD	GDSC;CCLE	10.919	Up-regulation
Other_PLK_PLK1_PLK1_ST	P35568	IRS1	P53350	PLK1	S372	P376L	376	Missense	distal	4	no	14.136	13.845	EPSD	GDSC;CCLE	10.919	Down-regulation
Other_PLK_PLK1_PLK1_ST	P35568	IRS1	P53350	PLK1	S415	R411*	411	Missense	distal	-4	no	11.677	11.441	EPSD	GDSC	10.919	Down-regulation
Other_PLK_PLK1_PLK1_ST	P35568	IRS1	P53350	PLK1	T552	A546V	546	Missense	distal	-6	no	11.154	10.915	EPSD	GDSC;CCLE	10.919	Loss
Other_PLK_PLK1_PLK1_ST	P35568	IRS1	P53350	PLK1	S741	P737S	737	Missense	distal	-4	no	11.207	11.328	EPSD	GDSC	10.919	Up-regulation
Other_PLK_PLK1_PLK1_ST	P35568	IRS1	P53350	PLK1	S1078	S1084R	1084	Missense	distal	6	no	11.775	11.468	EPSD	GDSC	10.919	Down-regulation
Other_PLK_PLK1_PLK1_ST	P35568	IRS1	P53350	PLK1	S1078	A1085D	1085	Missense	distal	7	no	11.775	11.723	EPSD	GDSC;CCLE	10.919	Down-regulation
Other_PLK_PLK1_PLK1_ST	P35568	IRS1	P53350	PLK1	S1227	S1233N	1233	Missense	distal	6	no	11.646	11.697	EPSD	GDSC;CCLE	10.919	Up-regulation
Other_PLK_PLK1_PLK1_ST	P35568	IRS1	P53350	PLK1	S1231	S1233N	1233	Missense	proximal	2	no	14.335	14.548	EPSD	GDSC;CCLE	10.919	Up-regulation
Other_PLK_PLK1_PLK1_ST	Q49MG5	MAP9	P53350	PLK1	S238	D237Y	237	Missense	proximal	-1	no	12.706	12.249	EPSD	GDSC	10.919	Down-regulation
Other_PLK_PLK1_PLK1_ST	Q49MG5	MAP9	P53350	PLK1	S238	C239Y	239	Missense	proximal	1	no	12.706	13.209	EPSD	GDSC;CCLE	10.919	Up-regulation
Other_PLK_PLK1_PLK1_ST	Q49MG5	MAP9	P53350	PLK1	S242	D237Y	237	Missense	distal	-5	no	10.949	10.804	EPSD	GDSC	10.919	Loss
Other_PLK_PLK1_PLK1_ST	Q49MG5	MAP9	P53350	PLK1	S242	C239Y	239	Missense	distal	-3	no	10.949	11.382	EPSD	GDSC;CCLE	10.919	Up-regulation
Other_PLK_PLK1_PLK1_ST	Q49MG5	MAP9	P53350	PLK1	S255	L252I	252	Missense	distal	-3	no	11.924	11.550	EPSD	GDSC;CCLE	10.919	Down-regulation
Other_PLK_PLK1_PLK1_ST	Q49MG5	MAP9	P53350	PLK1	T364	S363P	363	Missense	proximal	-1	no	11.677	10.503	EPSD	GDSC	10.919	Loss
Other_PLK_PLK1_PLK1_ST	O95613	PCNT	P53350	PLK1	T495	R494H	494	Missense	proximal	-1	no	10.244	11.241	EPSD	GDSC;CCLE	10.919	Gain
Other_PLK_PLK1_PLK1_ST	O95613	PCNT	P53350	PLK1	S1006	K1003E	1003	Missense	distal	-3	no	13.306	12.766	EPSD	GDSC;CCLE	10.919	Down-regulation
Other_PLK_PLK1_PLK1_ST	O95613	PCNT	P53350	PLK1	T1209	T1209I	1209	Missense	central	0	yes	12.997	0.000	EPSD;PhosphoSitePlus	GDSC	10.919	Loss
Other_PLK_PLK1_PLK1_ST	O95613	PCNT	P53350	PLK1	T1209	P1204S	1204	Missense	distal	-5	no	12.997	12.735	EPSD;PhosphoSitePlus	GDSC;CCLE	10.919	Down-regulation
Other_PLK_PLK1_PLK1_ST	O95613	PCNT	P53350	PLK1	T1221	C1225Y	1225	Missense	distal	4	no	14.108	14.392	PhosphoSitePlus;EPSD	GDSC;CCLE	10.919	Up-regulation
Other_PLK_PLK1_PLK1_ST	O95613	PCNT	P53350	PLK1	S1235	R1239H	1239	Missense	distal	4	no	10.566	10.990	EPSD;PhosphoSitePlus	GDSC	10.919	Gain
Other_PLK_PLK1_PLK1_ST	O95613	PCNT	P53350	PLK1	T1702	T1709A	1709	Missense	distal	7	no	10.980	11.020	EPSD	GDSC	10.919	Up-regulation
Other_PLK_PLK1_PLK1_ST	O95613	PCNT	P53350	PLK1	S2114	E2118G	2118	Missense	distal	4	no	13.884	13.810	EPSD	GDSC;CCLE	10.919	Down-regulation
Other_PLK_PLK1_PLK1_ST	O95613	PCNT	P53350	PLK1	S2189	S2183T	2183	Missense	distal	-6	no	12.182	12.079	EPSD	GDSC;CCLE	10.919	Down-regulation
Other_PLK_PLK1_PLK1_ST	O95613	PCNT	P53350	PLK1	S2433	T2439S	2439	Missense	distal	6	no	11.190	10.914	EPSD	GDSC;CCLE	10.919	Loss
Other_PLK_PLK1_PLK1_ST	O95613	PCNT	P53350	PLK1	S2860	K2867N	2867	Missense	distal	7	no	11.426	11.431	EPSD	GDSC;CCLE	10.919	Up-regulation
Other_PLK_PLK1_PLK1_ST	O95613	PCNT	P53350	PLK1	S2860	E2856Q	2856	Missense	distal	-4	no	11.426	11.157	EPSD	GDSC;CCLE	10.919	Down-regulation
Other_PLK_PLK1_PLK1_ST	O95613	PCNT	P53350	PLK1	S2900	S2894G	2894	Missense	distal	-6	no	11.419	10.873	EPSD	GDSC;CCLE	10.919	Loss
Other_PLK_PLK1_PLK1_ST	O95613	PCNT	P53350	PLK1	S3292	Q3297E	3297	Missense	distal	5	no	12.598	12.758	EPSD	GDSC;CCLE	10.919	Up-regulation
Other_PLK_PLK1_PLK1_ST	O95613	PCNT	P53350	PLK1	S3296	Q3297E	3297	Missense	proximal	1	no	12.449	12.326	EPSD	GDSC;CCLE	10.919	Down-regulation
Other_PLK_PLK1_PLK1_ST	O95613	PCNT	P53350	PLK1	S3302	Q3297E	3297	Missense	distal	-5	no	13.950	13.908	EPSD	GDSC;CCLE	10.919	Down-regulation
Other_PLK_PLK1_PLK1_ST	P30307	CDC25C	P53350	PLK1	S38	E34Q	34	Missense	distal	-4	no	12.316	12.048	EPSD	GDSC;CCLE	10.919	Down-regulation
Other_PLK_PLK1_PLK1_ST	P30307	CDC25C	P53350	PLK1	S75	G80R	80	Missense	distal	5	no	12.138	12.299	PhosphoSitePlus;EPSD	GDSC;CCLE	10.919	Up-regulation
Other_PLK_PLK1_PLK1_ST	P30307	CDC25C	P53350	PLK1	S451	R458Q	458	Missense	distal	7	no	11.295	11.310	EPSD	GDSC;CCLE	10.919	Up-regulation
Other_PLK_PLK1_PLK1_ST	P30307	CDC25C	P53350	PLK1	S472	M471T	471	Missense	proximal	-1	no	12.219	11.400	EPSD	GDSC;CCLE	10.919	Down-regulation
Other_PLK_PLK1_PLK1_ST	O43663	PRC1	P53350	PLK1	S11	V13L	13	Missense	proximal	2	no	11.568	11.436	EPSD	GDSC;CCLE	10.919	Down-regulation
Other_PLK_PLK1_PLK1_ST	O43663	PRC1	P53350	PLK1	S513	V515M	515	Missense	proximal	2	no	11.022	10.816	EPSD	GDSC;CCLE	10.919	Loss
Other_PLK_PLK1_PLK1_ST	Q7L2Z9	CENPQ	P53350	PLK1	T135	L141V	141	Missense	distal	6	no	11.453	11.521	EPSD;PhosphoSitePlus	GDSC;CCLE	10.919	Up-regulation
Other_PLK_PLK1_PLK1_ST	Q7L2Z9	CENPQ	P53350	PLK1	T135	N142D	142	Missense	distal	7	no	11.453	11.371	EPSD;PhosphoSitePlus	GDSC;CCLE	10.919	Down-regulation
Other_PLK_PLK1_PLK1_ST	Q7L2Z9	CENPQ	P53350	PLK1	T135	L140I	140	Missense	distal	5	no	11.453	12.097	EPSD;PhosphoSitePlus	GDSC;CCLE	10.919	Up-regulation
Other_PLK_PLK1_PLK1_ST	Q7L2Z9	CENPQ	P53350	PLK1	S138	L141V	141	Missense	distal	3	no	12.249	12.548	EPSD;PhosphoSitePlus	GDSC;CCLE	10.919	Up-regulation
Other_PLK_PLK1_PLK1_ST	Q7L2Z9	CENPQ	P53350	PLK1	S138	N142D	142	Missense	distal	4	no	12.249	12.488	EPSD;PhosphoSitePlus	GDSC;CCLE	10.919	Up-regulation
Other_PLK_PLK1_PLK1_ST	Q7L2Z9	CENPQ	P53350	PLK1	S138	L140I	140	Missense	proximal	2	no	12.249	12.599	EPSD;PhosphoSitePlus	GDSC;CCLE	10.919	Up-regulation
Other_PLK_PLK1_PLK1_ST	Q7L2Z9	CENPQ	P53350	PLK1	S139	L141V	141	Missense	proximal	2	no	10.825	10.957	EPSD;PhosphoSitePlus	GDSC;CCLE	10.919	Gain
Other_PLK_PLK1_PLK1_ST	Q7L2Z9	CENPQ	P53350	PLK1	S139	N142D	142	Missense	distal	3	no	10.825	11.025	EPSD;PhosphoSitePlus	GDSC;CCLE	10.919	Gain
Other_PLK_PLK1_PLK1_ST	Q7L2Z9	CENPQ	P53350	PLK1	T169	E170*	170	Missense	proximal	1	no	10.970	8.332	EPSD	GDSC	10.919	Loss
Other_PLK_PLK1_PLK1_ST	Q7L2Z9	CENPQ	P53350	PLK1	T173	E170*	170	Missense	distal	-3	no	12.399	13.121	EPSD	GDSC	10.919	Up-regulation
Other_PLK_PLK1_PLK1_ST	Q7L2Z9	CENPQ	P53350	PLK1	S255	Y262C	262	Missense	distal	7	no	11.102	11.115	PhosphoSitePlus;EPSD	GDSC	10.919	Up-regulation
Other_PLK_PLK1_PLK1_ST	Q7L2Z9	CENPQ	P53350	PLK1	T256	Y262C	262	Missense	distal	6	no	14.680	14.275	EPSD;PhosphoSitePlus	GDSC	10.919	Down-regulation
Other_PLK_PLK1_PLK1_ST	Q8IZD2	KMT2E	P53350	PLK1	S15	D10G	10	Missense	distal	-5	no	10.832	10.987	EPSD	GDSC;CCLE	10.919	Gain
Other_PLK_PLK1_PLK1_ST	Q8IZD2	KMT2E	P53350	PLK1	S499	D503G	503	Missense	distal	4	no	12.233	12.145	EPSD	GDSC;CCLE	10.919	Down-regulation
Other_PLK_PLK1_PLK1_ST	Q8IZD2	KMT2E	P53350	PLK1	S499	K496E	496	Missense	distal	-3	no	12.233	11.693	EPSD	GDSC;CCLE	10.919	Down-regulation
Other_PLK_PLK1_PLK1_ST	Q8IZD2	KMT2E	P53350	PLK1	T510	D503G	503	Missense	distal	-7	no	11.744	11.398	EPSD	GDSC;CCLE	10.919	Down-regulation
Other_PLK_PLK1_PLK1_ST	Q8IZD2	KMT2E	P53350	PLK1	S653	R656Q	656	Missense	distal	3	no	10.743	10.939	EPSD	GDSC;CCLE	10.919	Gain
Other_PLK_PLK1_PLK1_ST	Q8IZD2	KMT2E	P53350	PLK1	S829	E827G	827	Missense	proximal	-2	no	11.883	8.954	EPSD	GDSC;CCLE	10.919	Loss
Other_PLK_PLK1_PLK1_ST	Q8IZD2	KMT2E	P53350	PLK1	S861	S861N	861	Missense	central	0	yes	12.329	0.000	PhosphoSitePlus	GDSC;CCLE	10.919	Loss
Other_PLK_PLK1_PLK1_ST	Q8IZD2	KMT2E	P53350	PLK1	S909	P905A	905	Missense	distal	-4	no	15.640	15.801	EPSD	GDSC	10.919	Up-regulation
Other_PLK_PLK1_PLK1_ST	Q8IZD2	KMT2E	P53350	PLK1	S966	R963C	963	Missense	distal	-3	no	11.434	10.638	EPSD	GDSC	10.919	Loss
Other_PLK_PLK1_PLK1_ST	Q8IZD2	KMT2E	P53350	PLK1	T1088	Q1092*	1092	Missense	distal	4	no	11.129	10.067	EPSD	GDSC	10.919	Loss
Other_PLK_PLK1_PLK1_ST	Q9Y6D9	MAD1L1	P53350	PLK1	S699	R696H	696	Missense	distal	-3	no	10.982	10.310	EPSD	GDSC	10.919	Loss
Other_PLK_PLK1_PLK1_ST	Q99708	RBBP8	P53350	PLK1	S305	R300K	300	Missense	distal	-5	no	14.092	13.554	EPSD	GDSC;CCLE	10.919	Down-regulation
Other_PLK_PLK1_PLK1_ST	Q99708	RBBP8	P53350	PLK1	S349	G354R	354	Missense	distal	5	no	11.566	11.728	EPSD	GDSC;CCLE	10.919	Up-regulation
Other_PLK_PLK1_PLK1_ST	Q99708	RBBP8	P53350	PLK1	S649	Q643H	643	Missense	distal	-6	no	11.567	11.578	EPSD	GDSC;CCLE	10.919	Up-regulation
Other_PLK_PLK1_PLK1_ST	Q99708	RBBP8	P53350	PLK1	S649	Q643P	643	Missense	distal	-6	no	11.567	10.944	EPSD	GDSC	10.919	Down-regulation
Other_PLK_PLK1_PLK1_ST	Q99708	RBBP8	P53350	PLK1	S664	I657V	657	Missense	distal	-7	no	14.730	14.895	EPSD	GDSC;CCLE	10.919	Up-regulation
Other_PLK_PLK1_PLK1_ST	Q99708	RBBP8	P53350	PLK1	S723	M727T	727	Missense	distal	4	no	11.967	12.724	PhosphoSitePlus;EPSD	GDSC;CCLE	10.919	Up-regulation
Other_PLK_PLK1_PLK1_ST	Q99708	RBBP8	P53350	PLK1	S743	A741V	741	Missense	proximal	-2	no	13.958	13.918	EPSD	GDSC;CCLE	10.919	Down-regulation
Other_PLK_PLK1_PLK1_ST	Q99708	RBBP8	P53350	PLK1	S743	E737G	737	Missense	distal	-6	no	13.958	13.293	EPSD	GDSC;CCLE	10.919	Down-regulation
Other_PLK_PLK1_PLK1_ST	Q99708	RBBP8	P53350	PLK1	S789	G783C	783	Missense	distal	-6	no	11.693	11.037	EPSD;PhosphoSitePlus	GDSC;CCLE	10.919	Down-regulation
Other_PLK_PLK1_PLK1_ST	Q9BVS4	RIOK2	P53350	PLK1	S131	R133Q	133	Missense	proximal	2	no	11.981	12.306	EPSD	GDSC	10.919	Up-regulation
Other_PLK_PLK1_PLK1_ST	Q9BVS4	RIOK2	P53350	PLK1	S335	T328I	328	Missense	distal	-7	no	14.806	14.353	PhosphoSitePlus;EPSD	GDSC;CCLE	10.919	Down-regulation
Other_PLK_PLK1_PLK1_ST	Q9BVS4	RIOK2	P53350	PLK1	S380	E384Q	384	Missense	distal	4	no	14.193	13.790	EPSD;PhosphoSitePlus	GDSC;CCLE	10.919	Down-regulation
Other_PLK_PLK1_PLK1_ST	Q9BVS4	RIOK2	P53350	PLK1	S457	L455V	455	Missense	proximal	-2	no	12.037	13.025	EPSD	GDSC;CCLE	10.919	Up-regulation
Other_PLK_PLK1_PLK1_ST	Q9BVS4	RIOK2	P53350	PLK1	S457	P464S	464	Missense	distal	7	no	12.037	12.010	EPSD	GDSC;CCLE	10.919	Down-regulation
Other_PLK_PLK1_PLK1_ST	Q9BVS4	RIOK2	P53350	PLK1	S483	G488A	488	Missense	distal	5	no	10.787	11.170	EPSD	GDSC	10.919	Gain
Other_PLK_PLK1_PLK1_ST	Q14676	MDC1	P53350	PLK1	S136	R142Q	142	Missense	distal	6	no	10.680	10.968	EPSD	GDSC;CCLE	10.919	Gain
Other_PLK_PLK1_PLK1_ST	Q14676	MDC1	P53350	PLK1	S372	L369M	369	Missense	distal	-3	no	11.301	10.779	EPSD	GDSC;CCLE	10.919	Loss
Other_PLK_PLK1_PLK1_ST	Q14676	MDC1	P53350	PLK1	T378	E382*	382	Missense	distal	4	no	13.390	11.924	EPSD	GDSC	10.919	Down-regulation
Other_PLK_PLK1_PLK1_ST	Q14676	MDC1	P53350	PLK1	T404	S402N	402	Missense	proximal	-2	no	10.262	11.672	EPSD	GDSC;CCLE	10.919	Gain
Other_PLK_PLK1_PLK1_ST	Q14676	MDC1	P53350	PLK1	S485	L480F	480	Missense	distal	-5	no	10.999	10.074	EPSD	GDSC	10.919	Loss
Other_PLK_PLK1_PLK1_ST	Q14676	MDC1	P53350	PLK1	S498	D502N	502	Missense	distal	4	no	13.110	12.871	EPSD	GDSC;CCLE	10.919	Down-regulation
Other_PLK_PLK1_PLK1_ST	Q14676	MDC1	P53350	PLK1	S504	P506H	506	Missense	proximal	2	no	10.335	11.786	EPSD	GDSC;CCLE	10.919	Gain
Other_PLK_PLK1_PLK1_ST	Q14676	MDC1	P53350	PLK1	S513	P506H	506	Missense	distal	-7	no	10.946	11.039	EPSD	GDSC;CCLE	10.919	Up-regulation
Other_PLK_PLK1_PLK1_ST	Q14676	MDC1	P53350	PLK1	S513	R512K	512	Missense	proximal	-1	no	10.946	11.307	EPSD	GDSC;CCLE	10.919	Up-regulation
Other_PLK_PLK1_PLK1_ST	Q14676	MDC1	P53350	PLK1	T847	E851*	851	Missense	distal	4	no	11.387	9.921	EPSD;PhosphoSitePlus	GDSC	10.919	Loss
Other_PLK_PLK1_PLK1_ST	Q14676	MDC1	P53350	PLK1	S1171	P1170T	1170	Missense	proximal	-1	no	10.763	11.190	EPSD	GDSC	10.919	Gain
Other_PLK_PLK1_PLK1_ST	Q14676	MDC1	P53350	PLK1	S1171	Q1176R	1176	Missense	distal	5	no	10.763	11.559	EPSD	GDSC	10.919	Gain
Other_PLK_PLK1_PLK1_ST	Q14676	MDC1	P53350	PLK1	S1212	T1205A	1205	Missense	distal	-7	no	11.789	11.445	EPSD	GDSC	10.919	Down-regulation
Other_PLK_PLK1_PLK1_ST	Q14676	MDC1	P53350	PLK1	S1236	N1233S	1233	Missense	distal	-3	no	11.470	11.280	EPSD	GDSC	10.919	Down-regulation
Other_PLK_PLK1_PLK1_ST	Q14676	MDC1	P53350	PLK1	S1277	V1278G	1278	Missense	proximal	1	no	11.426	10.795	EPSD	GDSC	10.919	Loss
Other_PLK_PLK1_PLK1_ST	Q14676	MDC1	P53350	PLK1	S1294	V1301L	1301	Missense	distal	7	no	12.009	11.958	EPSD	GDSC	10.919	Down-regulation
Other_PLK_PLK1_PLK1_ST	Q14676	MDC1	P53350	PLK1	T1366	S1365*	1365	Missense	proximal	-1	no	11.738	8.505	EPSD	GDSC	10.919	Loss
Other_PLK_PLK1_PLK1_ST	Q14676	MDC1	P53350	PLK1	S1522	V1524L	1524	Missense	proximal	2	no	11.593	11.460	EPSD	GDSC	10.919	Down-regulation
Other_PLK_PLK1_PLK1_ST	Q14676	MDC1	P53350	PLK1	S1522	P1527H	1527	Missense	distal	5	no	11.593	10.899	EPSD	GDSC	10.919	Loss
Other_PLK_PLK1_PLK1_ST	Q14676	MDC1	P53350	PLK1	S1523	V1524L	1524	Missense	proximal	1	no	11.802	12.201	EPSD	GDSC	10.919	Up-regulation
Other_PLK_PLK1_PLK1_ST	Q14676	MDC1	P53350	PLK1	S1523	P1527H	1527	Missense	distal	4	no	11.802	11.603	EPSD	GDSC	10.919	Down-regulation
Other_PLK_PLK1_PLK1_ST	Q14676	MDC1	P53350	PLK1	T1560	G1558D	1558	Missense	proximal	-2	no	7.734	11.056	EPSD	GDSC	10.919	Gain
Other_PLK_PLK1_PLK1_ST	Q14676	MDC1	P53350	PLK1	S1563	G1558D	1558	Missense	distal	-5	no	10.963	10.808	EPSD	GDSC	10.919	Loss
Other_PLK_PLK1_PLK1_ST	Q14676	MDC1	P53350	PLK1	S1564	G1558D	1558	Missense	distal	-6	no	11.022	11.485	EPSD	GDSC	10.919	Up-regulation
Other_PLK_PLK1_PLK1_ST	Q14676	MDC1	P53350	PLK1	S1810	R1811L	1811	Missense	proximal	1	no	9.391	12.522	EPSD	GDSC;CCLE	10.919	Gain
Other_PLK_PLK1_PLK1_ST	Q14676	MDC1	P53350	PLK1	S1915	S1915C	1915	Missense	central	0	yes	11.282	0.000	EPSD	GDSC;CCLE	10.919	Loss
Other_PLK_PLK1_PLK1_ST	P49959	MRE11	P53350	PLK1	T12	V17I	17	Missense	distal	5	no	11.754	12.223	EPSD	GDSC	10.919	Up-regulation
Other_PLK_PLK1_PLK1_ST	P49959	MRE11	P53350	PLK1	S165	L169P	169	Missense	distal	4	no	12.739	13.030	EPSD	GDSC	10.919	Up-regulation
Other_PLK_PLK1_PLK1_ST	P49959	MRE11	P53350	PLK1	S558	E552K	552	Missense	distal	-6	no	11.002	10.429	EPSD	GDSC	10.919	Loss
Other_PLK_PLK1_PLK1_ST	P49959	MRE11	P53350	PLK1	S558	A564T	564	Missense	distal	6	no	11.002	10.995	EPSD	GDSC	10.919	Down-regulation
Other_PLK_PLK1_PLK1_ST	P49959	MRE11	P53350	PLK1	S561	A564T	564	Missense	distal	3	no	12.284	12.323	EPSD	GDSC	10.919	Up-regulation
Other_PLK_PLK1_PLK1_ST	P49959	MRE11	P53350	PLK1	S619	S613L	613	Missense	distal	-6	no	16.012	15.677	EPSD	GDSC	10.919	Down-regulation
Other_PLK_PLK1_PLK1_ST	P30260	CDC27	P53350	PLK1	T200	Q207K	207	Missense	distal	7	no	10.943	10.963	EPSD	GDSC;CCLE	10.919	Up-regulation
Other_PLK_PLK1_PLK1_ST	P30260	CDC27	P53350	PLK1	T205	Q207K	207	Missense	proximal	2	no	12.506	12.148	EPSD;PhosphoSitePlus	GDSC;CCLE	10.919	Down-regulation
Other_PLK_PLK1_PLK1_ST	Q6PGQ7	BORA	P53350	PLK1	S32	S27G	27	Missense	distal	-5	no	10.906	11.305	EPSD	GDSC;CCLE	10.919	Gain
Other_PLK_PLK1_PLK1_ST	Q6PGQ7	BORA	P53350	PLK1	S252	A258V	258	Missense	distal	6	no	11.263	11.088	EPSD	GDSC;CCLE	10.919	Down-regulation
Other_PLK_PLK1_PLK1_ST	Q6PGQ7	BORA	P53350	PLK1	S270	G264*	264	Missense	distal	-6	no	11.410	10.850	EPSD	GDSC	10.919	Loss
Other_PLK_PLK1_PLK1_ST	Q96CV9	OPTN	P53350	PLK1	S171	N169T	169	Missense	proximal	-2	no	13.110	11.162	EPSD	GDSC;CCLE	10.919	Down-regulation
Other_PLK_PLK1_PLK1_ST	Q96CV9	OPTN	P53350	PLK1	S171	L166V	166	Missense	distal	-5	no	13.110	12.657	EPSD	GDSC;CCLE	10.919	Down-regulation
Other_PLK_PLK1_PLK1_ST	Q96CV9	OPTN	P53350	PLK1	S216	R217T	217	Missense	proximal	1	no	9.997	11.753	EPSD	GDSC;CCLE	10.919	Gain
Other_PLK_PLK1_PLK1_ST	Q96CV9	OPTN	P53350	PLK1	S234	H228Y	228	Missense	distal	-6	no	11.744	10.879	EPSD	GDSC;CCLE	10.919	Loss
Other_PLK_PLK1_PLK1_ST	Q96CV9	OPTN	P53350	PLK1	S272	S269R	269	Missense	distal	-3	no	11.062	11.894	EPSD	GDSC;CCLE	10.919	Up-regulation
Other_PLK_PLK1_PLK1_ST	Q96CV9	OPTN	P53350	PLK1	S513	E516Q	516	Missense	distal	3	no	11.791	11.683	EPSD	GDSC;CCLE	10.919	Down-regulation
Other_PLK_PLK1_PLK1_ST	Q9HAW4	CLSPN	P53350	PLK1	S65	V61F	61	Missense	distal	-4	no	11.089	10.871	EPSD	GDSC	10.919	Loss
Other_PLK_PLK1_PLK1_ST	Q9HAW4	CLSPN	P53350	PLK1	S113	M115T	115	Missense	proximal	2	no	13.398	12.760	EPSD	GDSC;CCLE	10.919	Down-regulation
Other_PLK_PLK1_PLK1_ST	Q9HAW4	CLSPN	P53350	PLK1	S396	V402E	402	Missense	distal	6	no	11.288	11.302	EPSD	GDSC	10.919	Up-regulation
Other_PLK_PLK1_PLK1_ST	Q9HAW4	CLSPN	P53350	PLK1	S830	P832L	832	Missense	proximal	2	no	9.457	11.005	EPSD	GDSC	10.919	Gain
Other_PLK_PLK1_PLK1_ST	Q9HAW4	CLSPN	P53350	PLK1	S839	N844T	844	Missense	distal	5	no	12.769	12.768	EPSD	GDSC;CCLE	10.919	Down-regulation
Other_PLK_PLK1_PLK1_ST	Q9HAW4	CLSPN	P53350	PLK1	S839	I836V	836	Missense	distal	-3	no	12.769	12.493	EPSD	GDSC;CCLE	10.919	Down-regulation
Other_PLK_PLK1_PLK1_ST	Q9HAW4	CLSPN	P53350	PLK1	S839	P832L	832	Missense	distal	-7	no	12.769	12.675	EPSD	GDSC	10.919	Down-regulation
Other_PLK_PLK1_PLK1_ST	Q9HAW4	CLSPN	P53350	PLK1	S1204	M1207T	1207	Missense	distal	3	no	10.879	11.031	EPSD	GDSC;CCLE	10.919	Gain
Other_PLK_PLK1_PLK1_ST	Q9HAW4	CLSPN	P53350	PLK1	S1316	T1322I	1322	Missense	distal	6	no	10.945	10.670	EPSD	GDSC;CCLE	10.919	Loss
Other_PLK_PLK1_PLK1_ST	Q9HAW4	CLSPN	P53350	PLK1	S1325	T1322I	1322	Missense	distal	-3	no	13.277	13.300	EPSD	GDSC;CCLE	10.919	Up-regulation
Other_PLK_PLK1_PLK1_ST	Q9HAW4	CLSPN	P53350	PLK1	T1326	T1322I	1322	Missense	distal	-4	no	12.128	12.524	EPSD	GDSC;CCLE	10.919	Up-regulation
Other_PLK_PLK1_PLK1_ST	Q13526	PIN1	P53350	PLK1	S138	R142Q	142	Missense	distal	4	no	12.530	13.060	EPSD	GDSC	10.919	Up-regulation
Other_PLK_PLK1_PLK1_ST	Q13526	PIN1	P53350	PLK1	S147	R142Q	142	Missense	distal	-5	no	11.576	10.837	EPSD	GDSC	10.919	Loss
Other_PLK_PLK1_PLK1_ST	Q8NG31	KNL1	P53350	PLK1	S441	M437I	437	Missense	distal	-4	no	12.361	12.671	EPSD	GDSC	10.919	Up-regulation
Other_PLK_PLK1_PLK1_ST	Q8NG31	KNL1	P53350	PLK1	S497	P492A	492	Missense	distal	-5	no	11.349	11.370	EPSD	GDSC	10.919	Up-regulation
Other_PLK_PLK1_PLK1_ST	Q8NG31	KNL1	P53350	PLK1	S530	Q523H	523	Missense	distal	-7	no	12.901	12.880	EPSD	GDSC	10.919	Down-regulation
Other_PLK_PLK1_PLK1_ST	Q8NG31	KNL1	P53350	PLK1	T901	E907*	907	Missense	distal	6	no	11.145	10.157	EPSD	GDSC	10.919	Loss
Other_PLK_PLK1_PLK1_ST	Q8NG31	KNL1	P53350	PLK1	S1022	S1022I	1022	Missense	central	0	yes	11.150	0.000	EPSD	GDSC	10.919	Loss
Other_PLK_PLK1_PLK1_ST	Q8NG31	KNL1	P53350	PLK1	T1440	R1446*	1446	Missense	distal	6	no	11.231	10.671	EPSD	GDSC	10.919	Loss
Other_PLK_PLK1_PLK1_ST	Q8NG31	KNL1	P53350	PLK1	S1773	E1771A	1771	Missense	proximal	-2	no	11.093	8.916	EPSD	GDSC	10.919	Loss
Other_PLK_PLK1_PLK1_ST	Q8NG31	KNL1	P53350	PLK1	S1831	V1835L	1835	Missense	distal	4	no	11.917	11.766	EPSD	GDSC	10.919	Down-regulation
Other_PLK_PLK1_PLK1_ST	Q8NG31	KNL1	P53350	PLK1	S1864	Q1870*	1870	Missense	distal	6	no	12.317	11.469	EPSD	GDSC	10.919	Down-regulation
Other_PLK_PLK1_PLK1_ST	Q8NG31	KNL1	P53350	PLK1	T1879	L1876I	1876	Missense	distal	-3	no	11.981	11.607	EPSD	GDSC	10.919	Down-regulation
Other_PLK_PLK1_PLK1_ST	Q14674	ESPL1	P53350	PLK1	S325	A328V	328	Missense	distal	3	no	13.012	13.339	EPSD	GDSC;CCLE	10.919	Up-regulation
Other_PLK_PLK1_PLK1_ST	Q14674	ESPL1	P53350	PLK1	T1111	T1111I	1111	Missense	central	0	yes	11.985	0.000	EPSD	GDSC;CCLE	10.919	Loss
Other_PLK_PLK1_PLK1_ST	Q14674	ESPL1	P53350	PLK1	S1122	T1123I	1123	Missense	proximal	1	no	10.922	12.089	EPSD	GDSC;CCLE	10.919	Up-regulation
Other_PLK_PLK1_PLK1_ST	Q14674	ESPL1	P53350	PLK1	S1126	T1123I	1123	Missense	distal	-3	no	12.281	12.304	EPSD	GDSC;CCLE	10.919	Up-regulation
Other_PLK_PLK1_PLK1_ST	Q14674	ESPL1	P53350	PLK1	S1399	S1406L	1406	Missense	distal	7	no	15.258	15.256	PhosphoSitePlus;EPSD	GDSC;CCLE	10.919	Down-regulation
Other_PLK_PLK1_PLK1_ST	Q14674	ESPL1	P53350	PLK1	S1513	A1514S	1514	Missense	proximal	1	no	12.865	12.734	EPSD	GDSC;CCLE	10.919	Down-regulation
Other_PLK_PLK1_PLK1_ST	Q14674	ESPL1	P53350	PLK1	S1513	S1513L	1513	Missense	central	0	yes	12.865	0.000	EPSD	GDSC;CCLE	10.919	Loss
Other_PLK_PLK1_PLK1_ST	Q14674	ESPL1	P53350	PLK1	T1519	A1514S	1514	Missense	distal	-5	no	11.626	11.342	EPSD	GDSC;CCLE	10.919	Down-regulation
Other_PLK_PLK1_PLK1_ST	Q14674	ESPL1	P53350	PLK1	T1519	S1513L	1513	Missense	distal	-6	no	11.626	11.292	EPSD	GDSC;CCLE	10.919	Down-regulation
Other_PLK_PLK1_PLK1_ST	Q14674	ESPL1	P53350	PLK1	T1519	P1522T	1522	Missense	distal	3	no	11.626	11.467	EPSD	GDSC;CCLE	10.919	Down-regulation
Other_PLK_PLK1_PLK1_ST	O75170	PPP6R2	P53350	PLK1	T261	E262D	262	Missense	proximal	1	no	11.267	11.511	EPSD	GDSC	10.919	Up-regulation
Other_PLK_PLK1_PLK1_ST	O75170	PPP6R2	P53350	PLK1	T261	S267G	267	Missense	distal	6	no	11.267	11.063	EPSD	GDSC;CCLE	10.919	Down-regulation
Other_PLK_PLK1_PLK1_ST	O75170	PPP6R2	P53350	PLK1	S297	Y298N	298	Missense	proximal	1	no	11.628	11.630	EPSD	GDSC;CCLE	10.919	Up-regulation
Other_PLK_PLK1_PLK1_ST	O75170	PPP6R2	P53350	PLK1	S427	P433L	433	Missense	distal	6	no	11.505	11.400	EPSD	GDSC;CCLE	10.919	Down-regulation
Other_PLK_PLK1_PLK1_ST	Q8TCG1	CIP2A	P53350	PLK1	T828	E827D	827	Missense	proximal	-1	no	12.546	13.343	EPSD	GDSC	10.919	Up-regulation
Other_PLK_PLK1_PLK1_ST	Q8TCG1	CIP2A	P53350	PLK1	S847	S847R	847	Missense	central	0	yes	12.770	0.000	EPSD	GDSC	10.919	Loss
Other_PLK_PLK1_PLK1_ST	Q8TCG1	CIP2A	P53350	PLK1	S847	S847I	847	Missense	central	0	yes	12.770	0.000	EPSD	GDSC	10.919	Loss
Other_PLK_PLK1_PLK1_ST	O14920	IKBKB	P53350	PLK1	S733	F734L	734	Missense	proximal	1	no	16.117	15.037	EPSD;PhosphoSitePlus	GDSC	10.919	Down-regulation
Other_PLK_PLK1_PLK1_ST	O14920	IKBKB	P53350	PLK1	S740	F734L	734	Missense	distal	-6	no	12.084	12.267	PhosphoSitePlus;EPSD	GDSC	10.919	Up-regulation
Other_PLK_PLK1_PLK1_ST	O14920	IKBKB	P53350	PLK1	S750	A755V	755	Missense	distal	5	no	13.980	13.242	EPSD;PhosphoSitePlus	GDSC;CCLE	10.919	Down-regulation
Other_PLK_PLK1_PLK1_ST	P11388	TOP2A	P53350	PLK1	S312	A318P	318	Missense	distal	6	no	14.228	14.089	EPSD	GDSC;CCLE	10.919	Down-regulation
Other_PLK_PLK1_PLK1_ST	P11388	TOP2A	P53350	PLK1	S714	P716R	716	Missense	proximal	2	no	10.253	11.002	EPSD	GDSC;CCLE	10.919	Gain
Other_PLK_PLK1_PLK1_ST	P11388	TOP2A	P53350	PLK1	S1332	S1337L	1337	Missense	distal	5	no	11.846	11.500	EPSD	GDSC	10.919	Down-regulation
Other_PLK_PLK1_PLK1_ST	P11388	TOP2A	P53350	PLK1	S1337	S1337L	1337	Missense	central	0	yes	11.574	0.000	EPSD;PhosphoSitePlus	GDSC	10.919	Loss
Other_PLK_PLK1_PLK1_ST	P11388	TOP2A	P53350	PLK1	T1343	S1337L	1337	Missense	distal	-6	no	11.725	11.391	PhosphoSitePlus;EPSD	GDSC	10.919	Down-regulation
Other_PLK_PLK1_PLK1_ST	P11388	TOP2A	P53350	PLK1	S1354	S1361F	1361	Missense	distal	7	no	12.687	12.756	EPSD	GDSC	10.919	Up-regulation
Other_PLK_PLK1_PLK1_ST	P11388	TOP2A	P53350	PLK1	S1423	S1428P	1428	Missense	distal	5	no	11.535	11.922	EPSD	GDSC;CCLE	10.919	Up-regulation
Other_PLK_PLK1_PLK1_ST	P11388	TOP2A	P53350	PLK1	T1430	S1428P	1428	Missense	proximal	-2	no	11.178	10.594	EPSD	GDSC;CCLE	10.919	Loss
Other_PLK_PLK1_PLK1_ST	P11388	TOP2A	P53350	PLK1	T1430	R1435G	1435	Missense	distal	5	no	11.178	11.016	EPSD	GDSC	10.919	Down-regulation
Other_PLK_PLK1_PLK1_ST	P11388	TOP2A	P53350	PLK1	S1512	V1506M	1506	Missense	distal	-6	no	11.979	12.135	EPSD	GDSC;CCLE	10.919	Up-regulation
Other_PLK_PLK1_PLK1_ST	Q9UBW7	ZMYM2	P53350	PLK1	T116	I117F	117	Missense	proximal	1	no	10.616	11.905	EPSD	GDSC;CCLE	10.919	Gain
Other_PLK_PLK1_PLK1_ST	Q9UBW7	ZMYM2	P53350	PLK1	S159	S158T	158	Missense	proximal	-1	no	13.793	13.045	EPSD	GDSC;CCLE	10.919	Down-regulation
Other_PLK_PLK1_PLK1_ST	Q9UBW7	ZMYM2	P53350	PLK1	T1376	D1375N	1375	Missense	proximal	-1	no	10.933	10.000	EPSD	GDSC;CCLE	10.919	Loss
Other_PLK_PLK1_PLK1_ST	Q8NHV4	NEDD1	P53350	PLK1	T100	S94C	94	Missense	distal	-6	no	12.667	11.464	EPSD	GDSC	10.919	Down-regulation
Other_PLK_PLK1_PLK1_ST	Q13042	CDC16	P53350	PLK1	S112	L108V	108	Missense	distal	-4	no	12.015	12.108	PhosphoSitePlus	GDSC;CCLE	10.919	Up-regulation
Other_PLK_PLK1_PLK1_ST	Q13042	CDC16	P53350	PLK1	S595	S592Y	592	Missense	distal	-3	no	11.491	11.960	EPSD	GDSC;CCLE	10.919	Up-regulation
Other_PLK_PLK1_PLK1_ST	Q13042	CDC16	P53350	PLK1	T599	S592Y	592	Missense	distal	-7	no	17.407	16.794	EPSD	GDSC;CCLE	10.919	Down-regulation
Other_PLK_PLK1_PLK1_ST	P18031	PTPN1	P53350	PLK1	S70	A69D	69	Missense	proximal	-1	no	9.948	11.208	EPSD	GDSC;CCLE	10.919	Gain
Other_PLK_PLK1_PLK1_ST	P18031	PTPN1	P53350	PLK1	S286	M282L	282	Missense	distal	-4	no	14.986	15.069	PhosphoSitePlus;EPSD	GDSC;CCLE	10.919	Up-regulation
Other_PLK_PLK1_PLK1_ST	P18031	PTPN1	P53350	PLK1	S286	S285C	285	Missense	proximal	-1	no	14.986	13.126	PhosphoSitePlus;EPSD	GDSC;CCLE	10.919	Down-regulation
Other_PLK_PLK1_PLK1_ST	Q8N4N8	KIF2B	P53350	PLK1	T125	G128R	128	Missense	distal	3	no	11.675	11.548	PhosphoSitePlus;EPSD	GDSC	10.919	Down-regulation
Other_PLK_PLK1_PLK1_ST	Q8N4N8	KIF2B	P53350	PLK1	T125	G128E	128	Missense	distal	3	no	11.675	11.852	PhosphoSitePlus;EPSD	GDSC;CCLE	10.919	Up-regulation
Other_PLK_PLK1_PLK1_ST	Q8N4N8	KIF2B	P53350	PLK1	T125	D132Y	132	Missense	distal	7	no	11.675	11.757	PhosphoSitePlus;EPSD	GDSC;CCLE	10.919	Up-regulation
Other_PLK_PLK1_PLK1_ST	Q8N4N8	KIF2B	P53350	PLK1	S130	G128E	128	Missense	proximal	-2	no	8.866	11.794	EPSD	GDSC;CCLE	10.919	Gain
Other_PLK_PLK1_PLK1_ST	Q8N4N8	KIF2B	P53350	PLK1	S474	K473Q	473	Missense	proximal	-1	no	12.257	12.499	EPSD	GDSC;CCLE	10.919	Up-regulation
Other_PLK_PLK1_PLK1_ST	Q8N4N8	KIF2B	P53350	PLK1	S575	E573D	573	Missense	proximal	-2	no	11.721	12.114	EPSD	GDSC	10.919	Up-regulation
Other_PLK_PLK1_PLK1_ST	Q8N4N8	KIF2B	P53350	PLK1	S575	R578W	578	Missense	distal	3	no	11.721	11.492	EPSD	GDSC;CCLE	10.919	Down-regulation
Other_PLK_PLK1_PLK1_ST	Q9Y5T5	USP16	P53350	PLK1	S16	D14N	14	Missense	proximal	-2	no	13.082	11.840	EPSD	GDSC;CCLE	10.919	Down-regulation
Other_PLK_PLK1_PLK1_ST	Q9Y5T5	USP16	P53350	PLK1	S17	D14N	14	Missense	distal	-3	no	14.836	14.735	EPSD	GDSC;CCLE	10.919	Down-regulation
Other_PLK_PLK1_PLK1_ST	Q9Y5T5	USP16	P53350	PLK1	S751	H758N	758	Missense	distal	7	no	11.608	11.677	EPSD	GDSC	10.919	Up-regulation
Other_PLK_PLK1_PLK1_ST	O14641	DVL2	P53350	PLK1	T39	T39A	39	Missense	central	0	yes	12.315	0.000	EPSD	GDSC;CCLE	10.919	Loss
Other_PLK_PLK1_PLK1_ST	O14641	DVL2	P53350	PLK1	T39	V46L	46	Missense	distal	7	no	12.315	12.265	EPSD	GDSC;CCLE	10.919	Down-regulation
Other_PLK_PLK1_PLK1_ST	O14641	DVL2	P53350	PLK1	S281	G279D	279	Missense	proximal	-2	no	9.305	12.627	EPSD	GDSC;CCLE	10.919	Gain
Other_PLK_PLK1_PLK1_ST	O14641	DVL2	P53350	PLK1	S358	P357S	357	Missense	proximal	-1	no	10.595	11.769	EPSD	GDSC;CCLE	10.919	Gain
Other_PLK_PLK1_PLK1_ST	O14641	DVL2	P53350	PLK1	T364	P359S	359	Missense	distal	-5	no	11.285	11.023	EPSD	GDSC	10.919	Down-regulation
Other_PLK_PLK1_PLK1_ST	O14641	DVL2	P53350	PLK1	T364	P357S	357	Missense	distal	-7	no	11.285	11.496	EPSD	GDSC;CCLE	10.919	Up-regulation
Other_PLK_PLK1_PLK1_ST	O14641	DVL2	P53350	PLK1	T364	R367G	367	Missense	distal	3	no	11.285	11.412	EPSD	GDSC	10.919	Up-regulation
Other_PLK_PLK1_PLK1_ST	O14641	DVL2	P53350	PLK1	T595	R596Q	596	Missense	proximal	1	no	9.403	11.381	EPSD	GDSC;CCLE	10.919	Gain
Other_PLK_PLK1_PLK1_ST	O14641	DVL2	P53350	PLK1	S720	G726V	726	Missense	distal	6	no	12.586	12.898	EPSD	GDSC	10.919	Up-regulation
Other_PLK_PLK1_PLK1_ST	Q9H2D6	TRIOBP	P53350	PLK1	S294	Q297*	297	Missense	distal	3	no	11.684	11.053	EPSD	GDSC	10.919	Down-regulation
Other_PLK_PLK1_PLK1_ST	Q9H2D6	TRIOBP	P53350	PLK1	S300	Q297*	297	Missense	distal	-3	no	11.192	11.588	EPSD	GDSC	10.919	Up-regulation
Other_PLK_PLK1_PLK1_ST	Q9H2D6	TRIOBP	P53350	PLK1	S304	E308*	308	Missense	distal	4	no	12.189	10.724	EPSD	GDSC	10.919	Loss
Other_PLK_PLK1_PLK1_ST	Q9H2D6	TRIOBP	P53350	PLK1	S304	Q297*	297	Missense	distal	-7	no	12.189	11.422	EPSD	GDSC	10.919	Down-regulation
Other_PLK_PLK1_PLK1_ST	Q9H2D6	TRIOBP	P53350	PLK1	S324	T319I	319	Missense	distal	-5	no	11.428	11.581	EPSD	GDSC;CCLE	10.919	Up-regulation
Other_PLK_PLK1_PLK1_ST	Q9H2D6	TRIOBP	P53350	PLK1	S589	R582W	582	Missense	distal	-7	no	10.497	11.083	EPSD	GDSC	10.919	Gain
Other_PLK_PLK1_PLK1_ST	Q9H2D6	TRIOBP	P53350	PLK1	S638	R631Q	631	Missense	distal	-7	no	10.671	11.071	EPSD	GDSC;CCLE	10.919	Gain
Other_PLK_PLK1_PLK1_ST	Q9H2D6	TRIOBP	P53350	PLK1	S1124	R1127H	1127	Missense	distal	3	no	11.761	11.892	EPSD	GDSC;CCLE	10.919	Up-regulation
Other_PLK_PLK1_PLK1_ST	Q9H2D6	TRIOBP	P53350	PLK1	S1124	P1126S	1126	Missense	proximal	2	no	11.761	13.237	EPSD	GDSC;CCLE	10.919	Up-regulation
Other_PLK_PLK1_PLK1_ST	Q9H2D6	TRIOBP	P53350	PLK1	S1133	R1127H	1127	Missense	distal	-6	no	11.981	12.440	EPSD	GDSC;CCLE	10.919	Up-regulation
Other_PLK_PLK1_PLK1_ST	Q9H2D6	TRIOBP	P53350	PLK1	S1133	P1126S	1126	Missense	distal	-7	no	11.981	12.192	EPSD	GDSC;CCLE	10.919	Up-regulation
Other_PLK_PLK1_PLK1_ST	Q9H2D6	TRIOBP	P53350	PLK1	S2091	E2097G	2097	Missense	distal	6	no	11.860	11.534	EPSD	GDSC;CCLE	10.919	Down-regulation
Other_PLK_PLK1_PLK1_ST	Q9H2D6	TRIOBP	P53350	PLK1	S2091	E2087*	2087	Missense	distal	-4	no	11.860	11.066	EPSD	GDSC	10.919	Down-regulation
Other_PLK_PLK1_PLK1_ST	Q9H2D6	TRIOBP	P53350	PLK1	T2229	E2236K	2236	Missense	distal	7	no	11.598	11.671	EPSD	GDSC	10.919	Up-regulation
Other_PLK_PLK1_PLK1_ST	Q9H2D6	TRIOBP	P53350	PLK1	T2229	E2225*	2225	Missense	distal	-4	no	11.598	10.804	EPSD	GDSC	10.919	Loss
Other_PLK_PLK1_PLK1_ST	Q9H2D6	TRIOBP	P53350	PLK1	T2229	R2232C	2232	Missense	distal	3	no	11.598	11.657	EPSD	GDSC	10.919	Up-regulation
Other_PLK_PLK1_PLK1_ST	Q9H2D6	TRIOBP	P53350	PLK1	S2358	E2355D	2355	Missense	distal	-3	no	11.157	11.616	EPSD	GDSC	10.919	Up-regulation
Other_PLK_PLK1_PLK1_ST	Q9H2D6	TRIOBP	P53350	PLK1	S2362	E2355D	2355	Missense	distal	-7	no	11.432	11.143	EPSD	GDSC	10.919	Down-regulation
Other_PLK_PLK1_PLK1_ST	Q9H6R7	WDCP	P53350	PLK1	S259	M260T	260	Missense	proximal	1	no	11.395	9.264	EPSD	GDSC	10.919	Loss
Other_PLK_PLK1_PLK1_ST	Q9H6R7	WDCP	P53350	PLK1	S267	M260T	260	Missense	distal	-7	no	11.049	11.470	EPSD	GDSC	10.919	Up-regulation
Other_PLK_PLK1_PLK1_ST	Q9H6R7	WDCP	P53350	PLK1	S267	S274L	274	Missense	distal	7	no	11.049	11.047	EPSD	GDSC	10.919	Down-regulation
Other_PLK_PLK1_PLK1_ST	Q9H6R7	WDCP	P53350	PLK1	S274	S274L	274	Missense	central	0	yes	13.536	0.000	EPSD	GDSC	10.919	Loss
Other_PLK_PLK1_PLK1_ST	Q9H6R7	WDCP	P53350	PLK1	S510	S510F	510	Missense	central	0	yes	13.839	0.000	EPSD	GDSC	10.919	Loss
Other_PLK_PLK1_PLK1_ST	Q9H6R7	WDCP	P53350	PLK1	S695	V694A	694	Missense	proximal	-1	no	10.430	10.919	PhosphoSitePlus;EPSD	GDSC	10.919	Gain
Other_PLK_PLK1_PLK1_ST	Q9H6R7	WDCP	P53350	PLK1	S696	V694A	694	Missense	proximal	-2	no	11.831	11.872	EPSD	GDSC	10.919	Up-regulation
Other_PLK_PLK1_PLK1_ST	O60260	PRKN	P53350	PLK1	S108	V105L	105	Missense	distal	-3	no	12.200	12.850	EPSD	GDSC	10.919	Up-regulation
Other_PLK_PLK1_PLK1_ST	O60260	PRKN	P53350	PLK1	S108	P113T	113	Missense	distal	5	no	12.200	11.207	EPSD	GDSC	10.919	Down-regulation
Other_PLK_PLK1_PLK1_ST	Q00839	HNRNPU	P53350	PLK1	T286	V288A	288	Missense	proximal	2	no	13.810	13.366	EPSD	GDSC;CCLE	10.919	Down-regulation
Other_PLK_PLK1_PLK1_ST	Q00839	HNRNPU	P53350	PLK1	T582	R575L	575	Missense	distal	-7	no	11.635	11.827	EPSD	GDSC;CCLE	10.919	Up-regulation
Other_PLK_PLK1_PLK1_ST	Q9NS56	TOPORS	P53350	PLK1	S191	L184V	184	Missense	distal	-7	no	12.463	12.471	EPSD	GDSC;CCLE	10.919	Up-regulation
Other_PLK_PLK1_PLK1_ST	Q9NS56	TOPORS	P53350	PLK1	S498	P492A	492	Missense	distal	-6	no	11.379	11.967	EPSD	GDSC;CCLE	10.919	Up-regulation
Other_PLK_PLK1_PLK1_ST	Q9NS56	TOPORS	P53350	PLK1	S1032	S1028L	1028	Missense	distal	-4	no	12.908	12.715	EPSD	GDSC;CCLE	10.919	Down-regulation
Other_PLK_PLK1_PLK1_ST	P35222	CTNNB1	P53350	PLK1	S60	T59N	59	Missense	proximal	-1	no	11.105	11.712	EPSD	GDSC	10.919	Up-regulation
Other_PLK_PLK1_PLK1_ST	P35222	CTNNB1	P53350	PLK1	S129	A135V	135	Missense	distal	6	no	12.097	11.922	EPSD	GDSC;CCLE	10.919	Down-regulation
Other_PLK_PLK1_PLK1_ST	O94901	SUN1	P53350	PLK1	S75	G68D	68	Missense	distal	-7	no	12.337	12.684	EPSD	GDSC	10.919	Up-regulation
Other_PLK_PLK1_PLK1_ST	O94901	SUN1	P53350	PLK1	S75	S79G	79	Missense	distal	4	no	12.337	12.252	EPSD	GDSC	10.919	Down-regulation
Other_PLK_PLK1_PLK1_ST	O94901	SUN1	P53350	PLK1	S123	T121A	121	Missense	proximal	-2	no	10.959	11.578	EPSD	GDSC;CCLE	10.919	Up-regulation
Other_PLK_PLK1_PLK1_ST	O94901	SUN1	P53350	PLK1	S123	G120S	120	Missense	distal	-3	no	10.959	10.186	EPSD	GDSC	10.919	Loss
Other_PLK_PLK1_PLK1_ST	O94901	SUN1	P53350	PLK1	S123	T129I	129	Missense	distal	6	no	10.959	10.685	EPSD	GDSC;CCLE	10.919	Loss
Other_PLK_PLK1_PLK1_ST	O94901	SUN1	P53350	PLK1	S138	D136E	136	Missense	proximal	-2	no	14.201	13.808	PhosphoSitePlus	GDSC	10.919	Down-regulation
Other_PLK_PLK1_PLK1_ST	O94901	SUN1	P53350	PLK1	T199	A203T	203	Missense	distal	4	no	11.150	11.156	EPSD	GDSC;CCLE	10.919	Up-regulation
Other_PLK_PLK1_PLK1_ST	O94901	SUN1	P53350	PLK1	T199	S192F	192	Missense	distal	-7	no	11.150	10.692	EPSD	GDSC;CCLE	10.919	Loss
Other_PLK_PLK1_PLK1_ST	P06748	NPM1	P53350	PLK1	S43	N38D	38	Missense	distal	-5	no	10.805	11.101	EPSD	GDSC;CCLE	10.919	Gain
Other_PLK_PLK1_PLK1_ST	Q13158	FADD	P53350	PLK1	S69	R64H	64	Missense	distal	-5	no	11.094	10.291	EPSD	GDSC;CCLE	10.919	Loss
Other_PLK_PLK1_PLK1_ST	Q13158	FADD	P53350	PLK1	S69	H73N	73	Missense	distal	4	no	11.094	11.379	EPSD	GDSC;CCLE	10.919	Up-regulation
Other_PLK_PLK1_PLK1_ST	Q13158	FADD	P53350	PLK1	S69	L66P	66	Missense	distal	-3	no	11.094	9.902	EPSD	GDSC;CCLE	10.919	Loss
Other_PLK_PLK1_PLK1_ST	Q13158	FADD	P53350	PLK1	S69	L75V	75	Missense	distal	6	no	11.094	11.163	EPSD	GDSC;CCLE	10.919	Up-regulation
Other_PLK_PLK1_PLK1_ST	Q13158	FADD	P53350	PLK1	S203	E206K	206	Missense	distal	3	no	12.239	12.033	EPSD	GDSC	10.919	Down-regulation
Other_PLK_PLK1_PLK1_ST	P38398	BRCA1	P53350	PLK1	S123	I124V	124	Missense	proximal	1	no	14.179	13.988	EPSD	GDSC;CCLE	10.919	Down-regulation
Other_PLK_PLK1_PLK1_ST	P38398	BRCA1	P53350	PLK1	S187	S186F	186	Missense	proximal	-1	no	11.737	11.198	EPSD	GDSC;CCLE	10.919	Down-regulation
Other_PLK_PLK1_PLK1_ST	P38398	BRCA1	P53350	PLK1	T190	S186F	186	Missense	distal	-4	no	11.651	11.333	EPSD	GDSC;CCLE	10.919	Down-regulation
Other_PLK_PLK1_PLK1_ST	P38398	BRCA1	P53350	PLK1	S603	S603L	603	Missense	central	0	yes	12.032	0.000	EPSD	GDSC;CCLE	10.919	Loss
Other_PLK_PLK1_PLK1_ST	P38398	BRCA1	P53350	PLK1	S1480	A1481V	1481	Missense	proximal	1	no	9.574	11.012	EPSD	GDSC;CCLE	10.919	Gain
Other_PLK_PLK1_PLK1_ST	P38398	BRCA1	P53350	PLK1	S1484	A1481V	1481	Missense	distal	-3	no	13.037	12.638	EPSD	GDSC;CCLE	10.919	Down-regulation
Other_PLK_PLK1_PLK1_ST	P38398	BRCA1	P53350	PLK1	S1542	S1542C	1542	Missense	central	0	yes	12.204	0.000	EPSD	GDSC	10.919	Loss
Other_PLK_PLK1_PLK1_ST	P38398	BRCA1	P53350	PLK1	T1548	S1542C	1542	Missense	distal	-6	no	11.427	10.224	EPSD	GDSC	10.919	Loss
Other_PLK_PLK1_PLK1_ST	P38398	BRCA1	P53350	PLK1	S1580	P1579S	1579	Missense	proximal	-1	no	10.578	11.753	EPSD	GDSC;CCLE	10.919	Gain
Other_PLK_PLK1_PLK1_ST	P38398	BRCA1	P53350	PLK1	S1631	E1629V	1629	Missense	proximal	-2	no	12.214	9.996	EPSD	GDSC;CCLE	10.919	Loss
Other_PLK_PLK1_PLK1_ST	P38398	BRCA1	P53350	PLK1	S1631	M1628I	1628	Missense	distal	-3	no	12.214	12.362	EPSD	GDSC;CCLE	10.919	Up-regulation
Other_PLK_PLK1_PLK1_ST	P51587	BRCA2	P53350	PLK1	T203	T207A	207	Missense	distal	4	no	12.549	12.542	EPSD;PhosphoSitePlus	GDSC	10.919	Down-regulation
Other_PLK_PLK1_PLK1_ST	P51587	BRCA2	P53350	PLK1	T203	T207N	207	Missense	distal	4	no	12.549	12.505	EPSD;PhosphoSitePlus	GDSC;CCLE	10.919	Down-regulation
Other_PLK_PLK1_PLK1_ST	P51587	BRCA2	P53350	PLK1	S205	T207N	207	Missense	proximal	2	no	10.065	10.919	EPSD;PhosphoSitePlus	GDSC;CCLE	10.919	Gain
Other_PLK_PLK1_PLK1_ST	P51587	BRCA2	P53350	PLK1	S273	N277S	277	Missense	distal	4	no	11.890	12.126	EPSD	GDSC;CCLE	10.919	Up-regulation
Other_PLK_PLK1_PLK1_ST	P51587	BRCA2	P53350	PLK1	S642	K644R	644	Missense	proximal	2	no	11.371	11.404	EPSD	GDSC;CCLE	10.919	Up-regulation
Other_PLK_PLK1_PLK1_ST	P51587	BRCA2	P53350	PLK1	S648	K644R	644	Missense	distal	-4	no	10.931	10.758	EPSD	GDSC;CCLE	10.919	Loss
Other_PLK_PLK1_PLK1_ST	P51587	BRCA2	P53350	PLK1	T768	T774I	774	Missense	distal	6	no	14.092	13.818	EPSD	GDSC	10.919	Down-regulation
Other_PLK_PLK1_PLK1_ST	P51587	BRCA2	P53350	PLK1	T926	L929S	929	Missense	distal	3	no	11.657	11.804	EPSD	GDSC	10.919	Up-regulation
Other_PLK_PLK1_PLK1_ST	P51587	BRCA2	P53350	PLK1	T933	L929S	929	Missense	distal	-4	no	11.018	11.211	EPSD	GDSC	10.919	Up-regulation
Other_PLK_PLK1_PLK1_ST	P51587	BRCA2	P53350	PLK1	T2681	K2674N	2674	Missense	distal	-7	no	11.492	11.647	EPSD	GDSC;CCLE	10.919	Up-regulation
Other_PLK_PLK1_PLK1_ST	P51587	BRCA2	P53350	PLK1	S2701	S2705I	2705	Missense	distal	4	no	12.697	11.506	EPSD	GDSC;CCLE	10.919	Down-regulation
Other_PLK_PLK1_PLK1_ST	P51587	BRCA2	P53350	PLK1	S2701	K2707E	2707	Missense	distal	6	no	12.697	12.766	EPSD	GDSC;CCLE	10.919	Up-regulation
Other_PLK_PLK1_PLK1_ST	Q38SD2	LRRK1	P53350	PLK1	S1104	Y1098N	1098	Missense	distal	-6	no	10.656	11.313	EPSD	GDSC;CCLE	10.919	Gain
Other_PLK_PLK1_PLK1_ST	Q38SD2	LRRK1	P53350	PLK1	S1241	H1240Y	1240	Missense	proximal	-1	no	11.615	11.890	EPSD	GDSC;CCLE	10.919	Up-regulation
Other_PLK_PLK1_PLK1_ST	Q38SD2	LRRK1	P53350	PLK1	S1817	S1821G	1821	Missense	distal	4	no	13.695	13.610	PhosphoSitePlus	GDSC;CCLE	10.919	Down-regulation
Other_PLK_PLK1_PLK1_ST	Q38SD2	LRRK1	P53350	PLK1	S1817	V1816M	1816	Missense	proximal	-1	no	13.695	14.724	PhosphoSitePlus	GDSC	10.919	Up-regulation
Other_PLK_PLK1_PLK1_ST	Q9UBB4	ATXN10	P53350	PLK1	T426	R423*	423	Missense	distal	-3	no	11.561	11.282	EPSD	GDSC	10.919	Down-regulation
Other_PLK_PLK1_PLK1_ST	Q9UBB4	ATXN10	P53350	PLK1	S430	R423*	423	Missense	distal	-7	no	10.958	10.591	EPSD	GDSC	10.919	Loss
Other_PLK_PLK1_PLK1_ST	Q9UBB4	ATXN10	P53350	PLK1	S448	K451*	451	Missense	distal	3	no	15.036	14.504	EPSD	GDSC	10.919	Down-regulation
Other_PLK_PLK1_PLK1_ST	O95251	KAT7	P53350	PLK1	S21	T27I	27	Missense	distal	6	no	12.134	11.860	EPSD	GDSC;CCLE	10.919	Down-regulation
Other_PLK_PLK1_PLK1_ST	O95251	KAT7	P53350	PLK1	T27	T27I	27	Missense	central	0	yes	13.898	0.000	EPSD	GDSC;CCLE	10.919	Loss
Other_PLK_PLK1_PLK1_ST	O95251	KAT7	P53350	PLK1	S30	T27I	27	Missense	distal	-3	no	11.536	11.559	EPSD	GDSC;CCLE	10.919	Up-regulation
Other_PLK_PLK1_PLK1_ST	O95251	KAT7	P53350	PLK1	S124	P125L	125	Missense	proximal	1	no	12.875	13.721	EPSD	GDSC;CCLE	10.919	Up-regulation
Other_PLK_PLK1_PLK1_ST	Q13127	REST	P53350	PLK1	S96	G101D	101	Missense	distal	5	no	11.172	11.138	EPSD	GDSC;CCLE	10.919	Down-regulation
Other_PLK_PLK1_PLK1_ST	Q13127	REST	P53350	PLK1	S201	T205A	205	Missense	distal	4	no	13.019	13.013	EPSD	GDSC;CCLE	10.919	Down-regulation
Other_PLK_PLK1_PLK1_ST	Q13127	REST	P53350	PLK1	S204	T205A	205	Missense	proximal	1	no	13.943	13.481	EPSD	GDSC;CCLE	10.919	Down-regulation
Other_PLK_PLK1_PLK1_ST	Q13127	REST	P53350	PLK1	S942	T940S	940	Missense	proximal	-2	no	14.159	14.697	EPSD	GDSC;CCLE	10.919	Up-regulation
Other_PLK_PLK1_PLK1_ST	Q13127	REST	P53350	PLK1	S942	D941H	941	Missense	proximal	-1	no	14.159	13.427	EPSD	GDSC;CCLE	10.919	Down-regulation
Other_PLK_PLK1_PLK1_ST	P30622	CLIP1	P53350	PLK1	T36	S39N	39	Missense	distal	3	no	12.108	12.154	EPSD	GDSC;CCLE	10.919	Up-regulation
Other_PLK_PLK1_PLK1_ST	P30622	CLIP1	P53350	PLK1	S147	A142V	142	Missense	distal	-5	no	11.257	11.184	EPSD	GDSC	10.919	Down-regulation
Other_PLK_PLK1_PLK1_ST	P30622	CLIP1	P53350	PLK1	S147	T151A	151	Missense	distal	4	no	11.257	11.251	EPSD	GDSC;CCLE	10.919	Down-regulation
Other_PLK_PLK1_PLK1_ST	P30622	CLIP1	P53350	PLK1	S155	T151A	151	Missense	distal	-4	no	10.660	11.062	EPSD	GDSC;CCLE	10.919	Gain
Other_PLK_PLK1_PLK1_ST	Q76N32	CEP68	P53350	PLK1	S338	V334A	334	Missense	distal	-4	no	13.169	13.309	EPSD	GDSC	10.919	Up-regulation
Other_PLK_PLK1_PLK1_ST	Q76N32	CEP68	P53350	PLK1	S354	S354P	354	Missense	central	0	yes	11.324	0.000	EPSD	GDSC	10.919	Loss
Other_PLK_PLK1_PLK1_ST	Q76N32	CEP68	P53350	PLK1	S354	E361*	361	Missense	distal	7	no	11.324	11.470	EPSD	GDSC	10.919	Up-regulation
Other_PLK_PLK1_PLK1_ST	Q76N32	CEP68	P53350	PLK1	S577	L580P	580	Missense	distal	3	no	11.352	11.521	EPSD	GDSC;CCLE	10.919	Up-regulation
Other_PLK_PLK1_PLK1_ST	P42898	MTHFR	P53350	PLK1	S465	E470V	470	Missense	distal	5	no	13.975	14.095	EPSD	GDSC	10.919	Up-regulation
Other_PLK_PLK1_PLK1_ST	P42898	MTHFR	P53350	PLK1	S465	E470Q	470	Missense	distal	5	no	13.975	13.816	EPSD	GDSC	10.919	Down-regulation
Other_PLK_PLK1_PLK1_ST	Q15435	PPP1R7	P53350	PLK1	S24	R20Q	20	Missense	distal	-4	no	12.419	12.707	EPSD;PhosphoSitePlus	GDSC	10.919	Up-regulation
Other_PLK_PLK1_PLK1_ST	Q15435	PPP1R7	P53350	PLK1	S27	R20Q	20	Missense	distal	-7	no	12.421	12.821	EPSD;PhosphoSitePlus	GDSC	10.919	Up-regulation
Other_PLK_PLK1_PLK1_ST	Q15435	PPP1R7	P53350	PLK1	S47	R54W	54	Missense	distal	7	no	13.541	13.560	EPSD;PhosphoSitePlus	GDSC	10.919	Up-regulation
Other_PLK_PLK1_PLK1_ST	Q15468	STIL	P53350	PLK1	T237	R242C	242	Missense	distal	5	no	13.348	13.132	EPSD	GDSC;CCLE	10.919	Down-regulation
Other_PLK_PLK1_PLK1_ST	Q9UJX5	ANAPC4	P53350	PLK1	S285	R286H	286	Missense	proximal	1	no	11.078	12.475	EPSD	GDSC;CCLE	10.919	Up-regulation
Other_PLK_PLK1_PLK1_ST	Q9UJX5	ANAPC4	P53350	PLK1	T446	K443R	443	Missense	distal	-3	no	14.000	14.460	EPSD	GDSC;CCLE	10.919	Up-regulation
Other_PLK_PLK1_PLK1_ST	Q9UJX5	ANAPC4	P53350	PLK1	T446	F447L	447	Missense	proximal	1	no	14.000	12.919	EPSD	GDSC;CCLE	10.919	Down-regulation
Other_PLK_PLK1_PLK1_ST	Q92574	TSC1	P53350	PLK1	S115	L116V	116	Missense	proximal	1	no	11.424	11.025	EPSD	GDSC	10.919	Down-regulation
Other_PLK_PLK1_PLK1_ST	Q92574	TSC1	P53350	PLK1	S115	P111A	111	Missense	distal	-4	no	11.424	11.585	EPSD	GDSC;CCLE	10.919	Up-regulation
Other_PLK_PLK1_PLK1_ST	Q92574	TSC1	P53350	PLK1	S374	G378R	378	Missense	distal	4	no	11.007	10.148	EPSD	GDSC	10.919	Loss
Other_PLK_PLK1_PLK1_ST	Q92574	TSC1	P53350	PLK1	S1116	L1121M	1121	Missense	distal	5	no	11.499	11.942	EPSD	GDSC;CCLE	10.919	Up-regulation
Other_PLK_PLK1_PLK1_ST	O60566	BUB1B	P53350	PLK1	T471	E476*	476	Missense	distal	5	no	12.126	13.377	EPSD	GDSC	10.919	Up-regulation
Other_PLK_PLK1_PLK1_ST	O60566	BUB1B	P53350	PLK1	S543	P545S	545	Missense	proximal	2	no	9.787	11.264	EPSD	GDSC;CCLE	10.919	Gain
Other_PLK_PLK1_PLK1_ST	O60566	BUB1B	P53350	PLK1	S574	V573M	573	Missense	proximal	-1	no	11.781	12.810	EPSD	GDSC	10.919	Up-regulation
Other_PLK_PLK1_PLK1_ST	O60566	BUB1B	P53350	PLK1	S676	H681P	681	Missense	distal	5	no	12.761	13.454	EPSD;PhosphoSitePlus	GDSC;CCLE	10.919	Up-regulation
Other_PLK_PLK1_PLK1_ST	O60566	BUB1B	P53350	PLK1	T680	H681P	681	Missense	proximal	1	no	13.297	14.186	EPSD;PhosphoSitePlus	GDSC;CCLE	10.919	Up-regulation
Other_PLK_PLK1_PLK1_ST	O60566	BUB1B	P53350	PLK1	S683	H681P	681	Missense	proximal	-2	no	11.145	11.096	EPSD	GDSC;CCLE	10.919	Down-regulation
Other_PLK_PLK1_PLK1_ST	O60566	BUB1B	P53350	PLK1	S884	R886S	886	Missense	proximal	2	no	13.111	13.839	EPSD	GDSC;CCLE	10.919	Up-regulation
Other_PLK_PLK1_PLK1_ST	O60566	BUB1B	P53350	PLK1	T1008	S1010F	1010	Missense	proximal	2	no	11.310	10.759	PhosphoSitePlus;EPSD	GDSC;CCLE	10.919	Loss
Other_PLK_PLK1_PLK1_ST	O60566	BUB1B	P53350	PLK1	T1008	N1004S	1004	Missense	distal	-4	no	11.310	11.445	PhosphoSitePlus;EPSD	GDSC	10.919	Up-regulation
Other_PLK_PLK1_PLK1_ST	O60566	BUB1B	P53350	PLK1	T1008	T1008A	1008	Missense	central	0	yes	11.310	0.000	PhosphoSitePlus;EPSD	GDSC;CCLE	10.919	Loss
Other_PLK_PLK1_PLK1_ST	Q6IBW4	NCAPH2	P53350	PLK1	T403	Q408*	408	Missense	distal	5	no	9.905	11.316	EPSD	GDSC	10.919	Gain
Other_PLK_PLK1_PLK1_ST	P14635	CCNB1	P53350	PLK1	S133	E140D	140	Missense	distal	7	no	12.250	12.246	PhosphoSitePlus;EPSD	GDSC;CCLE	10.919	Down-regulation
Other_PLK_PLK1_PLK1_ST	P14635	CCNB1	P53350	PLK1	S133	E140Q	140	Missense	distal	7	no	12.250	12.303	PhosphoSitePlus;EPSD	GDSC;CCLE	10.919	Up-regulation
Other_PLK_PLK1_PLK1_ST	P14635	CCNB1	P53350	PLK1	S370	E374K	374	Missense	distal	4	no	13.928	13.554	EPSD	GDSC;CCLE	10.919	Down-regulation
Other_PLK_PLK1_PLK1_ST	Q08050	FOXM1	P53350	PLK1	S306	I310T	310	Missense	distal	4	no	11.603	12.602	EPSD	GDSC;CCLE	10.919	Up-regulation
Other_PLK_PLK1_PLK1_ST	Q9Y266	NUDC	P53350	PLK1	S136	L137F	137	Missense	proximal	1	no	10.092	11.172	EPSD	GDSC;CCLE	10.919	Gain
Other_PLK_PLK1_PLK1_ST	Q9Y266	NUDC	P53350	PLK1	S231	E225V	225	Missense	distal	-6	no	11.497	11.103	EPSD	GDSC;CCLE	10.919	Down-regulation
Other_PLK_PLK1_PLK1_ST	Q9Y266	NUDC	P53350	PLK1	S274	L279P	279	Missense	distal	5	no	13.799	14.533	PhosphoSitePlus;EPSD	GDSC;CCLE	10.919	Up-regulation
Other_PLK_PLK1_PLK1_ST	Q9Y266	NUDC	P53350	PLK1	S285	L279P	279	Missense	distal	-6	no	11.476	11.187	EPSD	GDSC;CCLE	10.919	Down-regulation
Other_PLK_PLK1_PLK1_ST	Q9Y2T1	AXIN2	P53350	PLK1	S70	P71L	71	Missense	proximal	1	no	10.463	11.309	EPSD	GDSC;CCLE	10.919	Gain
Other_PLK_PLK1_PLK1_ST	Q8TEP8	CEP192	P53350	PLK1	S136	A140T	140	Missense	distal	4	no	12.300	12.306	EPSD	GDSC;CCLE	10.919	Up-regulation
Other_PLK_PLK1_PLK1_ST	Q8TEP8	CEP192	P53350	PLK1	T153	K148E	148	Missense	distal	-5	no	12.449	12.206	EPSD	GDSC	10.919	Down-regulation
Other_PLK_PLK1_PLK1_ST	Q8TEP8	CEP192	P53350	PLK1	S164	H165D	165	Missense	proximal	1	no	11.799	12.501	EPSD	GDSC	10.919	Up-regulation
Other_PLK_PLK1_PLK1_ST	Q8TEP8	CEP192	P53350	PLK1	S208	T212I	212	Missense	distal	4	no	12.695	11.696	EPSD	GDSC	10.919	Down-regulation
Other_PLK_PLK1_PLK1_ST	Q8TEP8	CEP192	P53350	PLK1	S216	T212I	212	Missense	distal	-4	no	10.618	11.014	EPSD	GDSC	10.919	Gain
Other_PLK_PLK1_PLK1_ST	Q8TEP8	CEP192	P53350	PLK1	S278	A279T	279	Missense	proximal	1	no	10.561	11.023	EPSD	GDSC	10.919	Gain
Other_PLK_PLK1_PLK1_ST	Q8TEP8	CEP192	P53350	PLK1	S373	N366T	366	Missense	distal	-7	no	12.943	13.144	EPSD	GDSC;CCLE	10.919	Up-regulation
Other_PLK_PLK1_PLK1_ST	Q8TEP8	CEP192	P53350	PLK1	S387	Q385E	385	Missense	proximal	-2	no	9.008	11.667	EPSD	GDSC	10.919	Gain
Other_PLK_PLK1_PLK1_ST	Q8TEP8	CEP192	P53350	PLK1	S453	T457A	457	Missense	distal	4	no	11.036	11.030	EPSD	GDSC	10.919	Down-regulation
Other_PLK_PLK1_PLK1_ST	Q8TEP8	CEP192	P53350	PLK1	S516	E523K	523	Missense	distal	7	no	11.940	12.013	EPSD	GDSC;CCLE	10.919	Up-regulation
Other_PLK_PLK1_PLK1_ST	Q8TEP8	CEP192	P53350	PLK1	S516	A521T	521	Missense	distal	5	no	11.940	10.768	EPSD	GDSC;CCLE	10.919	Loss
Other_PLK_PLK1_PLK1_ST	Q8TEP8	CEP192	P53350	PLK1	S516	I511V	511	Missense	distal	-5	no	11.940	11.783	EPSD	GDSC	10.919	Down-regulation
Other_PLK_PLK1_PLK1_ST	Q8TEP8	CEP192	P53350	PLK1	T1488	S1494C	1494	Missense	distal	6	no	12.774	11.841	EPSD	GDSC;CCLE	10.919	Down-regulation
Other_PLK_PLK1_PLK1_ST	Q8TEP8	CEP192	P53350	PLK1	T1488	G1495W	1495	Missense	distal	7	no	12.774	12.810	EPSD	GDSC	10.919	Up-regulation
Other_PLK_PLK1_PLK1_ST	Q8TEP8	CEP192	P53350	PLK1	S1502	G1495W	1495	Missense	distal	-7	no	12.066	12.851	EPSD	GDSC	10.919	Up-regulation
Other_PLK_PLK1_PLK1_ST	Q8TEP8	CEP192	P53350	PLK1	S1602	S1608P	1608	Missense	distal	6	no	12.525	12.669	EPSD	GDSC;CCLE	10.919	Up-regulation
Other_PLK_PLK1_PLK1_ST	Q8TEP8	CEP192	P53350	PLK1	T1637	Q1638*	1638	Missense	proximal	1	no	11.595	8.834	EPSD	GDSC	10.919	Loss
Other_PLK_PLK1_PLK1_ST	Q99640	PKMYT1	P53350	PLK1	S100	R101W	101	Missense	proximal	1	no	9.607	12.311	EPSD	GDSC;CCLE	10.919	Gain
Other_PLK_PLK1_PLK1_ST	Q99640	PKMYT1	P53350	PLK1	S426	D432E	432	Missense	distal	6	no	15.084	14.935	EPSD;PhosphoSitePlus	GDSC	10.919	Down-regulation
Other_PLK_PLK1_PLK1_ST	Q99640	PKMYT1	P53350	PLK1	S469	S473*	473	Missense	distal	4	no	13.246	11.769	EPSD	GDSC	10.919	Down-regulation
Other_PLK_PLK1_PLK1_ST	Q99640	PKMYT1	P53350	PLK1	T495	P498L	498	Missense	distal	3	no	12.543	12.374	PhosphoSitePlus;EPSD	GDSC;CCLE	10.919	Down-regulation
Other_PLK_PLK1_PLK1_ST	O60216	RAD21	P53350	PLK1	S134	Q132*	132	Missense	proximal	-2	no	11.727	6.438	EPSD	GDSC	10.919	Loss
Other_PLK_PLK1_PLK1_ST	O60216	RAD21	P53350	PLK1	S134	R139S	139	Missense	distal	5	no	11.727	11.382	EPSD	GDSC;CCLE	10.919	Down-regulation
Other_PLK_PLK1_PLK1_ST	O60216	RAD21	P53350	PLK1	S138	Q132*	132	Missense	distal	-6	no	11.704	10.598	EPSD	GDSC	10.919	Loss
Other_PLK_PLK1_PLK1_ST	O60216	RAD21	P53350	PLK1	S138	R139S	139	Missense	proximal	1	no	11.704	12.868	EPSD	GDSC;CCLE	10.919	Up-regulation
Other_PLK_PLK1_PLK1_ST	O60216	RAD21	P53350	PLK1	T144	R139S	139	Missense	distal	-5	no	15.810	15.126	EPSD	GDSC;CCLE	10.919	Down-regulation
Other_PLK_PLK1_PLK1_ST	O60216	RAD21	P53350	PLK1	S280	S277T	277	Missense	distal	-3	no	10.971	11.347	EPSD	GDSC;CCLE	10.919	Up-regulation
Other_PLK_PLK1_PLK1_ST	O60216	RAD21	P53350	PLK1	S342	D343N	343	Missense	proximal	1	no	11.135	10.940	EPSD	GDSC;CCLE	10.919	Down-regulation
Other_PLK_PLK1_PLK1_ST	O60216	RAD21	P53350	PLK1	S345	D343N	343	Missense	proximal	-2	no	14.335	13.092	EPSD	GDSC;CCLE	10.919	Down-regulation
Other_PLK_PLK1_PLK1_ST	O60216	RAD21	P53350	PLK1	S466	S466A	466	Missense	central	0	yes	11.619	0.000	EPSD	GDSC;CCLE	10.919	Loss
Other_PLK_PLK1_PLK1_ST	O43379	WDR62	P53350	PLK1	S445	S445N	445	Missense	central	0	yes	13.091	0.000	EPSD	GDSC;CCLE	10.919	Loss
Other_PLK_PLK1_PLK1_ST	O43379	WDR62	P53350	PLK1	S445	R438C	438	Missense	distal	-7	no	13.091	12.970	EPSD	GDSC;CCLE	10.919	Down-regulation
Other_PLK_PLK1_PLK1_ST	O43379	WDR62	P53350	PLK1	S445	S445R	445	Missense	central	0	yes	13.091	0.000	EPSD	GDSC;CCLE	10.919	Loss
Other_PLK_PLK1_PLK1_ST	O43379	WDR62	P53350	PLK1	S987	P983R	983	Missense	distal	-4	no	12.627	12.183	EPSD	GDSC;CCLE	10.919	Down-regulation
Other_PLK_PLK1_PLK1_ST	O43379	WDR62	P53350	PLK1	S1038	P1032S	1032	Missense	distal	-6	no	10.547	11.170	EPSD	GDSC;CCLE	10.919	Gain
Other_PLK_PLK1_PLK1_ST	Q92994	BRF1	P53350	PLK1	T270	L264I	264	Missense	distal	-6	no	12.520	12.923	EPSD	GDSC	10.919	Up-regulation
Other_PLK_PLK1_PLK1_ST	O96017	CHEK2	P53350	PLK1	T68	S73F	73	Missense	distal	5	no	11.890	11.984	PhosphoSitePlus;EPSD	GDSC;CCLE	10.919	Up-regulation
Other_PLK_PLK1_PLK1_ST	O60285	NUAK1	P53350	PLK1	S325	E324D	324	Missense	proximal	-1	no	10.430	11.227	EPSD	GDSC;CCLE	10.919	Gain
Other_PLK_PLK1_PLK1_ST	O60285	NUAK1	P53350	PLK1	S455	A448V	448	Missense	distal	-7	no	11.278	11.335	EPSD	GDSC	10.919	Up-regulation
Other_PLK_PLK1_PLK1_ST	O60285	NUAK1	P53350	PLK1	S481	E475Q	475	Missense	distal	-6	no	13.272	13.152	EPSD	GDSC;CCLE	10.919	Down-regulation
Other_PLK_PLK1_PLK1_ST	O60285	NUAK1	P53350	PLK1	S516	V512L	512	Missense	distal	-4	no	11.243	11.150	EPSD	GDSC;CCLE	10.919	Down-regulation
Other_PLK_PLK1_PLK1_ST	O60285	NUAK1	P53350	PLK1	S550	G555S	555	Missense	distal	5	no	15.347	15.164	EPSD	GDSC;CCLE	10.919	Down-regulation
Other_PLK_PLK1_PLK1_ST	P08670	VIM	P53350	PLK1	S293	E300K	300	Missense	distal	7	no	11.059	11.132	EPSD	GDSC;CCLE	10.919	Up-regulation
Other_PLK_PLK1_PLK1_ST	P08670	VIM	P53350	PLK1	S299	E300K	300	Missense	proximal	1	no	13.360	12.910	EPSD	GDSC;CCLE	10.919	Down-regulation
Other_PLK_PLK1_PLK1_ST	P08670	VIM	P53350	PLK1	S325	A332V	332	Missense	distal	7	no	11.748	11.771	EPSD	GDSC;CCLE	10.919	Up-regulation
Other_PLK_PLK1_PLK1_ST	P08670	VIM	P53350	PLK1	S430	P432S	432	Missense	proximal	2	no	10.922	12.398	EPSD	GDSC;CCLE	10.919	Up-regulation
Other_PLK_PLK1_PLK1_ST	P08670	VIM	P53350	PLK1	S430	S430L	430	Missense	central	0	yes	10.922	0.000	EPSD	GDSC;CCLE	10.919	Loss
Other_PLK_PLK1_PLK1_ST	P08670	VIM	P53350	PLK1	S459	T458A	458	Missense	proximal	-1	no	11.973	12.253	EPSD	GDSC;CCLE	10.919	Up-regulation
Other_PLK_PLK1_PLK1_ST	O95425	SVIL	P53350	PLK1	S66	L67V	67	Missense	proximal	1	no	13.619	13.220	EPSD	GDSC;CCLE	10.919	Down-regulation
Other_PLK_PLK1_PLK1_ST	O95425	SVIL	P53350	PLK1	S315	S319I	319	Missense	distal	4	no	13.327	12.135	EPSD	GDSC;CCLE	10.919	Down-regulation
Other_PLK_PLK1_PLK1_ST	O95425	SVIL	P53350	PLK1	S918	S913P	913	Missense	distal	-5	no	13.078	13.340	EPSD	GDSC;CCLE	10.919	Up-regulation
Other_PLK_PLK1_PLK1_ST	O95425	SVIL	P53350	PLK1	S920	S913P	913	Missense	distal	-7	no	11.777	11.566	EPSD	GDSC;CCLE	10.919	Down-regulation
Other_PLK_PLK1_PLK1_ST	O95425	SVIL	P53350	PLK1	S938	N940I	940	Missense	proximal	2	no	11.444	11.652	EPSD	GDSC;CCLE	10.919	Up-regulation
Other_PLK_PLK1_PLK1_ST	O95425	SVIL	P53350	PLK1	S968	S968F	968	Missense	central	0	yes	14.941	0.000	EPSD	GDSC;CCLE	10.919	Loss
Other_PLK_PLK1_PLK1_ST	Q9UJX2	CDC23	P53350	PLK1	T134	G139A	139	Missense	distal	5	no	12.873	13.257	EPSD	GDSC	10.919	Up-regulation
Other_PLK_PLK1_PLK1_ST	Q9UJX2	CDC23	P53350	PLK1	T134	E133*	133	Missense	proximal	-1	no	12.873	9.644	EPSD	GDSC	10.919	Loss
Other_PLK_PLK1_PLK1_ST	P30291	WEE1	P53350	PLK1	S242	P240L	240	Missense	proximal	-2	no	11.613	11.249	EPSD	GDSC;CCLE	10.919	Down-regulation
Other_PLK_PLK1_PLK1_ST	P30291	WEE1	P53350	PLK1	S289	I286V	286	Missense	distal	-3	no	12.095	11.820	EPSD	GDSC	10.919	Down-regulation
Other_PLK_PLK1_PLK1_ST	P30291	WEE1	P53350	PLK1	S289	N290S	290	Missense	proximal	1	no	12.095	11.355	EPSD	GDSC	10.919	Down-regulation
Other_PLK_PLK1_PLK1_ST	P30291	WEE1	P53350	PLK1	S289	Y295H	295	Missense	distal	6	no	12.095	12.100	EPSD	GDSC;CCLE	10.919	Up-regulation
Other_PLK_PLK1_PLK1_ST	O60341	KDM1A	P53350	PLK1	S126	R121G	121	Missense	distal	-5	no	16.215	15.930	PhosphoSitePlus	GDSC;CCLE	10.919	Down-regulation
Other_PLK_PLK1_PLK1_ST	O60341	KDM1A	P53350	PLK1	S172	E167*	167	Missense	distal	-5	no	12.204	12.852	EPSD	GDSC	10.919	Up-regulation
Other_PLK_PLK1_PLK1_ST	O15350	TP73	P53350	PLK1	T167	T167P	167	Missense	central	0	yes	11.790	0.000	EPSD	GDSC	10.919	Loss
Other_PLK_PLK1_PLK1_ST	Q9Y265	RUVBL1	P53350	PLK1	S19	I15M	15	Missense	distal	-4	no	11.064	10.754	EPSD	GDSC;CCLE	10.919	Loss
Other_PLK_PLK1_PLK1_ST	Q00613	HSF1	P53350	PLK1	S314	P308L	308	Missense	distal	-6	no	11.515	11.804	EPSD	GDSC	10.919	Up-regulation
Other_PLK_PLK1_PLK1_ST	Q00613	HSF1	P53350	PLK1	S314	E312A	312	Missense	proximal	-2	no	11.515	9.337	EPSD	GDSC	10.919	Loss
Other_PLK_PLK1_PLK1_ST	Q00613	HSF1	P53350	PLK1	T355	R360Q	360	Missense	distal	5	no	11.033	10.237	EPSD	GDSC	10.919	Loss
Other_PLK_PLK1_PLK1_ST	Q00613	HSF1	P53350	PLK1	T355	R360W	360	Missense	distal	5	no	11.033	10.775	EPSD	GDSC;CCLE	10.919	Loss
Other_PLK_PLK1_PLK1_ST	Q00613	HSF1	P53350	PLK1	S457	S458I	458	Missense	proximal	1	no	11.726	13.485	EPSD	GDSC;CCLE	10.919	Up-regulation
Other_PLK_PLK1_PLK1_ST	P36507	MAP2K2	P53350	PLK1	T17	E20D	20	Missense	distal	3	no	10.988	11.053	EPSD	GDSC	10.919	Up-regulation
Other_PLK_PLK1_PLK1_ST	P36507	MAP2K2	P53350	PLK1	S222	S222C	222	Missense	central	0	yes	13.658	0.000	EPSD;PhosphoSitePlus	GDSC;CCLE	10.919	Loss
Other_PLK_PLK1_PLK1_ST	P36507	MAP2K2	P53350	PLK1	S226	S222C	222	Missense	distal	-4	no	14.657	13.844	PhosphoSitePlus;EPSD	GDSC;CCLE	10.919	Down-regulation
Other_PLK_PLK1_PLK1_ST	P30626	SRI	P53350	PLK1	S149	R147*	147	Missense	proximal	-2	no	11.805	6.341	EPSD	GDSC	10.919	Loss
Other_PLK_PLK1_PLK1_ST	P30626	SRI	P53350	PLK1	S172	R176W	176	Missense	distal	4	no	12.409	12.948	EPSD	GDSC	10.919	Up-regulation
Other_PLK_PLK1_PLK1_ST	Q07817	BCL2L1	P53350	PLK1	S62	P55S	55	Missense	distal	-7	no	12.434	12.644	PhosphoSitePlus	GDSC;CCLE	10.919	Up-regulation
Other_PLK_PLK1_PLK1_ST	Q07817	BCL2L1	P53350	PLK1	S62	T69I	69	Missense	distal	7	no	12.434	12.481	PhosphoSitePlus	GDSC;CCLE	10.919	Up-regulation
Other_PLK_PLK1_PLK1_ST	Q07817	BCL2L1	P53350	PLK1	S62	G67V	67	Missense	distal	5	no	12.434	12.079	PhosphoSitePlus	GDSC;CCLE	10.919	Down-regulation
Other_PLK_PLK1_PLK1_ST	P54274	TERF1	P53350	PLK1	T24	D17G	17	Missense	distal	-7	no	11.790	11.444	EPSD	GDSC	10.919	Down-regulation
Other_PLK_PLK1_PLK1_ST	P54274	TERF1	P53350	PLK1	T24	R19K	19	Missense	distal	-5	no	11.790	11.252	EPSD	GDSC;CCLE	10.919	Down-regulation
Other_PLK_PLK1_PLK1_ST	Q2NKX8	ERCC6L	P53350	PLK1	S1086	S1089C	1089	Missense	distal	3	no	12.621	12.557	EPSD	GDSC	10.919	Down-regulation
Other_PLK_PLK1_PLK1_ST	Q2NKX8	ERCC6L	P53350	PLK1	S1173	A1169T	1169	Missense	distal	-4	no	11.507	11.105	EPSD	GDSC;CCLE	10.919	Down-regulation
Other_PLK_PLK1_PLK1_ST	Q2NKX8	ERCC6L	P53350	PLK1	S1173	L1174I	1174	Missense	proximal	1	no	11.507	11.298	EPSD	GDSC;CCLE	10.919	Down-regulation
Other_PLK_PLK1_PLK1_ST	Q2NKX8	ERCC6L	P53350	PLK1	S1242	Y1244H	1244	Missense	proximal	2	no	12.027	12.369	EPSD	GDSC	10.919	Up-regulation
Other_PLK_PLK1_PLK1_ST	P46937	YAP1	P53350	PLK1	S94	P98L	98	Missense	distal	4	no	11.592	11.301	EPSD	GDSC;CCLE	10.919	Down-regulation
Other_PLK_PLK1_PLK1_ST	P46937	YAP1	P53350	PLK1	S164	R161*	161	Missense	distal	-3	no	12.625	12.346	EPSD	GDSC	10.919	Down-regulation
Other_PLK_PLK1_PLK1_ST	P46937	YAP1	P53350	PLK1	S257	T255N	255	Missense	proximal	-2	no	9.031	10.979	EPSD	GDSC	10.919	Gain
Other_PLK_PLK1_PLK1_ST	P46937	YAP1	P53350	PLK1	S499	S499G	499	Missense	central	0	yes	11.760	0.000	EPSD	GDSC;CCLE	10.919	Loss
Other_PLK_PLK1_PLK1_ST	Q96T23	RSF1	P53350	PLK1	S471	S475A	475	Missense	distal	4	no	10.932	10.733	EPSD	GDSC	10.919	Loss
Other_PLK_PLK1_PLK1_ST	Q96T23	RSF1	P53350	PLK1	S471	D477Y	477	Missense	distal	6	no	10.932	10.133	EPSD	GDSC;CCLE	10.919	Loss
Other_PLK_PLK1_PLK1_ST	Q96T23	RSF1	P53350	PLK1	S473	S475A	475	Missense	proximal	2	no	11.468	11.229	EPSD	GDSC	10.919	Down-regulation
Other_PLK_PLK1_PLK1_ST	Q96T23	RSF1	P53350	PLK1	S473	D477Y	477	Missense	distal	4	no	11.468	11.223	EPSD	GDSC;CCLE	10.919	Down-regulation
Other_PLK_PLK1_PLK1_ST	Q96T23	RSF1	P53350	PLK1	S544	K548E	548	Missense	distal	4	no	12.136	12.510	EPSD	GDSC;CCLE	10.919	Up-regulation
Other_PLK_PLK1_PLK1_ST	Q96T23	RSF1	P53350	PLK1	S695	P694S	694	Missense	proximal	-1	no	10.327	11.501	EPSD	GDSC	10.919	Gain
Other_PLK_PLK1_PLK1_ST	Q96T23	RSF1	P53350	PLK1	T812	A813P	813	Missense	proximal	1	no	11.720	12.711	EPSD	GDSC;CCLE	10.919	Up-regulation
Other_PLK_PLK1_PLK1_ST	Q96T23	RSF1	P53350	PLK1	T817	A813P	813	Missense	distal	-4	no	11.051	10.890	EPSD	GDSC;CCLE	10.919	Loss
Other_PLK_PLK1_PLK1_ST	Q96T23	RSF1	P53350	PLK1	S858	R851C	851	Missense	distal	-7	no	11.865	11.745	EPSD	GDSC;CCLE	10.919	Down-regulation
Other_PLK_PLK1_PLK1_ST	Q96T23	RSF1	P53350	PLK1	S1064	I1063T	1063	Missense	proximal	-1	no	12.183	11.419	EPSD	GDSC	10.919	Down-regulation
Other_PLK_PLK1_PLK1_ST	Q96T23	RSF1	P53350	PLK1	S1105	E1108*	1108	Missense	distal	3	no	12.874	12.135	EPSD	GDSC	10.919	Down-regulation
Other_PLK_PLK1_PLK1_ST	Q96T23	RSF1	P53350	PLK1	S1192	D1190E	1190	Missense	proximal	-2	no	13.469	13.075	EPSD	GDSC	10.919	Down-regulation
Other_PLK_PLK1_PLK1_ST	Q96T23	RSF1	P53350	PLK1	S1196	D1190E	1190	Missense	distal	-6	no	11.764	11.967	EPSD	GDSC	10.919	Up-regulation
Other_PLK_PLK1_PLK1_ST	Q96T23	RSF1	P53350	PLK1	S1252	E1259K	1259	Missense	distal	7	no	11.095	11.168	EPSD	GDSC;CCLE	10.919	Up-regulation
Other_PLK_PLK1_PLK1_ST	Q96T23	RSF1	P53350	PLK1	S1282	E1283K	1283	Missense	proximal	1	no	11.399	10.949	EPSD	GDSC;CCLE	10.919	Down-regulation
Other_PLK_PLK1_PLK1_ST	Q96T23	RSF1	P53350	PLK1	S1310	G1316E	1316	Missense	distal	6	no	11.127	11.453	EPSD	GDSC;CCLE	10.919	Up-regulation
Other_PLK_PLK1_PLK1_ST	Q96T23	RSF1	P53350	PLK1	S1310	D1312G	1312	Missense	proximal	2	no	11.127	9.548	EPSD	GDSC;CCLE	10.919	Loss
Other_PLK_PLK1_PLK1_ST	Q8TD19	NEK9	P53350	PLK1	T662	A665V	665	Missense	distal	3	no	12.975	13.303	EPSD	GDSC	10.919	Up-regulation
Other_PLK_PLK1_PLK1_ST	Q8TD19	NEK9	P53350	PLK1	T662	T666A	666	Missense	distal	4	no	12.975	12.969	EPSD	GDSC;CCLE	10.919	Down-regulation
Other_PLK_PLK1_PLK1_ST	Q13416	ORC2	P53350	PLK1	S96	S103Y	103	Missense	distal	7	no	11.345	11.400	EPSD	GDSC	10.919	Up-regulation
Other_PLK_PLK1_PLK1_ST	Q13416	ORC2	P53350	PLK1	S96	K93R	93	Missense	distal	-3	no	11.345	11.806	EPSD	GDSC;CCLE	10.919	Up-regulation
Other_PLK_PLK1_PLK1_ST	Q13416	ORC2	P53350	PLK1	T132	N134S	134	Missense	proximal	2	no	12.926	12.712	EPSD	GDSC;CCLE	10.919	Down-regulation
Other_PLK_PLK1_PLK1_ST	Q13416	ORC2	P53350	PLK1	S177	H176Y	176	Missense	proximal	-1	no	11.229	11.504	EPSD	GDSC;CCLE	10.919	Up-regulation
Other_PLK_PLK1_PLK1_ST	Q13416	ORC2	P53350	PLK1	S179	H176Y	176	Missense	distal	-3	no	11.399	11.708	EPSD	GDSC;CCLE	10.919	Up-regulation
CMGC_CDK_CDK8_CDK19_ST	P46531	NOTCH1	Q9BWU1	CDK19	T2132	P2133S	2133	Missense	proximal	1	no	2.184	2.220	EPSD	GDSC	1.856	Up-regulation
CMGC_CDK_CDK8_CDK19_ST	O00303	EIF3F	Q9BWU1	CDK19	S105	D104Y	104	Missense	proximal	-1	no	2.988	3.023	EPSD	GDSC;CCLE	1.856	Up-regulation
CMGC_CDK_CDK8_CDK19_ST	O00303	EIF3F	Q9BWU1	CDK19	S295	A300S	300	Missense	distal	5	no	2.907	2.913	EPSD	GDSC;CCLE	1.856	Up-regulation
CMGC_CDK_CDK8_CDK19_ST	O00303	EIF3F	Q9BWU1	CDK19	S295	S295F	295	Missense	central	0	yes	2.907	0.000	EPSD	GDSC	1.856	Loss
CMGC_CDK_CDK8_CDK19_ST	Q13153	PAK1	Q9BWU1	CDK19	S156	A163V	163	Missense	distal	7	no	1.672	2.098	EPSD	GDSC;CCLE	1.856	Gain
CMGC_CDK_CDK5_CDK5_ST	O60331	PIP5K1C	Q00535	CDK5	S539	T543M	543	Missense	distal	4	no	17.824	17.732	EPSD	GDSC	8.808	Down-regulation
CMGC_CDK_CDK5_CDK5_ST	Q07820	MCL1	Q00535	CDK5	S121	M120V	120	Missense	proximal	-1	no	17.010	17.015	EPSD	GDSC	8.808	Up-regulation
CMGC_CDK_CDK5_CDK5_ST	P49023	PXN	Q00535	CDK5	S85	S83F	83	Missense	proximal	-2	no	17.443	16.884	PhosphoSitePlus;EPSD	GDSC	8.808	Down-regulation
CMGC_CDK_CDK5_CDK5_ST	P49023	PXN	Q00535	CDK5	S85	V87E	87	Missense	proximal	2	no	17.443	17.354	PhosphoSitePlus;EPSD	GDSC	8.808	Down-regulation
CMGC_CDK_CDK5_CDK5_ST	P49023	PXN	Q00535	CDK5	S130	P129L	129	Missense	proximal	-1	no	18.453	18.448	EPSD	GDSC	8.808	Down-regulation
CMGC_CDK_CDK5_CDK5_ST	P49023	PXN	Q00535	CDK5	S188	G191R	191	Missense	distal	3	no	18.052	19.434	EPSD	GDSC;CCLE	8.808	Up-regulation
CMGC_CDK_CDK5_CDK5_ST	P49023	PXN	Q00535	CDK5	S188	S188R	188	Missense	central	0	yes	18.052	0.000	EPSD	GDSC	8.808	Loss
CMGC_CDK_CDK5_CDK5_ST	P49023	PXN	Q00535	CDK5	S303	R301G	301	Missense	proximal	-2	no	17.358	16.948	EPSD	GDSC	8.808	Down-regulation
CMGC_CDK_CDK5_CDK5_ST	P49023	PXN	Q00535	CDK5	S303	S302G	302	Missense	proximal	-1	no	17.358	17.353	EPSD	GDSC	8.808	Down-regulation
CMGC_CDK_CDK5_CDK5_ST	P49023	PXN	Q00535	CDK5	S303	G305R	305	Missense	proximal	2	no	17.358	17.530	EPSD	GDSC	8.808	Up-regulation
CMGC_CDK_CDK5_CDK5_ST	P49023	PXN	Q00535	CDK5	S320	S321N	321	Missense	proximal	1	no	6.246	8.909	EPSD	GDSC;CCLE	8.808	Gain
CMGC_CDK_CDK5_CDK5_ST	P49023	PXN	Q00535	CDK5	S322	S321N	321	Missense	proximal	-1	no	17.843	17.840	EPSD	GDSC;CCLE	8.808	Down-regulation
CMGC_CDK_CDK5_CDK5_ST	P10636	MAPT	Q00535	CDK5	S46	Q49H	49	Missense	distal	3	no	17.321	18.105	EPSD	GDSC	8.808	Up-regulation
CMGC_CDK_CDK5_CDK5_ST	P10636	MAPT	Q00535	CDK5	S46	A41V	41	Missense	distal	-5	no	17.321	17.446	EPSD	GDSC;CCLE	8.808	Up-regulation
CMGC_CDK_CDK5_CDK5_ST	P10636	MAPT	Q00535	CDK5	T50	Q49H	49	Missense	proximal	-1	no	17.042	17.041	EPSD	GDSC	8.808	Down-regulation
CMGC_CDK_CDK5_CDK5_ST	P10636	MAPT	Q00535	CDK5	S228	R222H	222	Missense	distal	-6	no	17.027	16.961	EPSD	GDSC;CCLE	8.808	Down-regulation
CMGC_CDK_CDK5_CDK5_ST	P10636	MAPT	Q00535	CDK5	T470	A475V	475	Missense	distal	5	no	16.586	16.683	EPSD	GDSC;CCLE	8.808	Up-regulation
CMGC_CDK_CDK5_CDK5_ST	P10636	MAPT	Q00535	CDK5	S739	S739C	739	Missense	central	0	yes	17.183	0.000	EPSD	GDSC	8.808	Loss
CMGC_CDK_CDK5_CDK5_ST	P42858	HTT	Q00535	CDK5	T486	H492R	492	Missense	distal	6	no	17.017	17.028	EPSD	GDSC;CCLE	8.808	Up-regulation
CMGC_CDK_CDK5_CDK5_ST	P42858	HTT	Q00535	CDK5	S1179	L1178V	1178	Missense	proximal	-1	no	19.777	19.781	EPSD;PhosphoSitePlus	GDSC;CCLE	8.808	Up-regulation
CMGC_CDK_CDK5_CDK5_ST	P42858	HTT	Q00535	CDK5	S2074	P2081Q	2081	Missense	distal	7	no	18.577	18.573	EPSD	GDSC;CCLE	8.808	Down-regulation
CMGC_CDK_CDK5_CDK5_ST	P42858	HTT	Q00535	CDK5	S2094	P2095L	2095	Missense	proximal	1	no	19.112	7.162	EPSD	GDSC;CCLE	8.808	Loss
CMGC_CDK_CDK5_CDK5_ST	P42858	HTT	Q00535	CDK5	T2335	E2341K	2341	Missense	distal	6	no	17.802	17.820	EPSD	GDSC;CCLE	8.808	Up-regulation
CMGC_CDK_CDK5_CDK5_ST	P42858	HTT	Q00535	CDK5	T2335	K2337R	2337	Missense	proximal	2	no	17.802	17.753	EPSD	GDSC	8.808	Down-regulation
CMGC_CDK_CDK5_CDK5_ST	P42858	HTT	Q00535	CDK5	S2421	P2424S	2424	Missense	distal	3	no	18.344	18.324	EPSD	GDSC;CCLE	8.808	Down-regulation
CMGC_CDK_CDK5_CDK5_ST	P42858	HTT	Q00535	CDK5	S2651	A2648E	2648	Missense	distal	-3	no	18.695	18.704	EPSD	GDSC;CCLE	8.808	Up-regulation
CMGC_CDK_CDK5_CDK5_ST	P42858	HTT	Q00535	CDK5	S2655	A2648E	2648	Missense	distal	-7	no	18.601	18.610	EPSD	GDSC;CCLE	8.808	Up-regulation
CMGC_CDK_CDK5_CDK5_ST	P42858	HTT	Q00535	CDK5	S2812	L2814P	2814	Missense	proximal	2	no	10.851	11.017	EPSD	GDSC;CCLE	8.808	Up-regulation
CMGC_CDK_CDK5_CDK5_ST	P04150	NR3C1	Q00535	CDK5	S52	Q53H	53	Missense	proximal	1	no	8.918	-0.618	EPSD	GDSC;CCLE	8.808	Loss
CMGC_CDK_CDK5_CDK5_ST	Q8NEB9	PIK3C3	Q00535	CDK5	T159	T166S	166	Missense	distal	7	no	19.273	19.274	EPSD;PhosphoSitePlus	GDSC;CCLE	8.808	Up-regulation
CMGC_CDK_CDK5_CDK5_ST	Q8NEB9	PIK3C3	Q00535	CDK5	S244	G240D	240	Missense	distal	-4	no	16.661	16.826	EPSD	GDSC;CCLE	8.808	Up-regulation
CMGC_CDK_CDK5_CDK5_ST	P56817	BACE1	Q00535	CDK5	T252	Y245H	245	Missense	distal	-7	no	19.204	19.239	PhosphoSitePlus	GDSC;CCLE	8.808	Up-regulation
CMGC_CDK_CDK5_CDK5_ST	P05067	APP	Q00535	CDK5	T381	H388Y	388	Missense	distal	7	no	16.419	16.411	EPSD	GDSC;CCLE	8.808	Down-regulation
CMGC_CDK_CDK5_CDK5_ST	P49418	AMPH	Q00535	CDK5	T260	I257F	257	Missense	distal	-3	no	17.115	17.062	EPSD	GDSC;CCLE	8.808	Down-regulation
CMGC_CDK_CDK5_CDK5_ST	P49418	AMPH	Q00535	CDK5	T260	P261T	261	Missense	proximal	1	no	17.115	6.628	EPSD	GDSC;CCLE	8.808	Loss
CMGC_CDK_CDK5_CDK5_ST	P49418	AMPH	Q00535	CDK5	S262	I257F	257	Missense	distal	-5	no	17.302	17.105	EPSD	GDSC;CCLE	8.808	Down-regulation
CMGC_CDK_CDK5_CDK5_ST	P49418	AMPH	Q00535	CDK5	S268	P261T	261	Missense	distal	-7	no	17.965	17.955	EPSD	GDSC;CCLE	8.808	Down-regulation
CMGC_CDK_CDK5_CDK5_ST	P49418	AMPH	Q00535	CDK5	S268	L270F	270	Missense	proximal	2	no	17.965	17.903	EPSD	GDSC;CCLE	8.808	Down-regulation
CMGC_CDK_CDK5_CDK5_ST	P49418	AMPH	Q00535	CDK5	S272	P277S	277	Missense	distal	5	no	18.353	18.365	EPSD;PhosphoSitePlus	GDSC	8.808	Up-regulation
CMGC_CDK_CDK5_CDK5_ST	P49418	AMPH	Q00535	CDK5	S272	L270F	270	Missense	proximal	-2	no	18.353	18.110	EPSD;PhosphoSitePlus	GDSC;CCLE	8.808	Down-regulation
CMGC_CDK_CDK5_CDK5_ST	P49418	AMPH	Q00535	CDK5	S276	P277S	277	Missense	proximal	1	no	18.246	6.345	EPSD;PhosphoSitePlus	GDSC	8.808	Loss
CMGC_CDK_CDK5_CDK5_ST	P49418	AMPH	Q00535	CDK5	S276	L270F	270	Missense	distal	-6	no	18.246	18.195	EPSD;PhosphoSitePlus	GDSC;CCLE	8.808	Down-regulation
CMGC_CDK_CDK5_CDK5_ST	P49418	AMPH	Q00535	CDK5	S285	R292Q	292	Missense	distal	7	no	17.350	17.345	PhosphoSitePlus;EPSD	GDSC;CCLE	8.808	Down-regulation
CMGC_CDK_CDK5_CDK5_ST	P49418	AMPH	Q00535	CDK5	S293	R292Q	292	Missense	proximal	-1	no	16.929	16.927	EPSD	GDSC;CCLE	8.808	Down-regulation
CMGC_CDK_CDK5_CDK5_ST	P49418	AMPH	Q00535	CDK5	S295	P302T	302	Missense	distal	7	no	10.870	10.869	EPSD	GDSC;CCLE	8.808	Down-regulation
CMGC_CDK_CDK5_CDK5_ST	P49418	AMPH	Q00535	CDK5	S295	R292Q	292	Missense	distal	-3	no	10.870	10.844	EPSD	GDSC;CCLE	8.808	Down-regulation
CMGC_CDK_CDK5_CDK5_ST	P49418	AMPH	Q00535	CDK5	T310	T310N	310	Missense	central	0	yes	18.925	0.000	EPSD	GDSC;CCLE	8.808	Loss
CMGC_CDK_CDK5_CDK5_ST	P49418	AMPH	Q00535	CDK5	T310	P304Q	304	Missense	distal	-6	no	18.925	18.913	EPSD	GDSC;CCLE	8.808	Down-regulation
CMGC_CDK_CDK5_CDK5_ST	Q96QB1	DLC1	Q00535	CDK5	S306	Q303R	303	Missense	distal	-3	no	19.469	19.495	EPSD	GDSC;CCLE	8.808	Up-regulation
CMGC_CDK_CDK5_CDK5_ST	Q96QB1	DLC1	Q00535	CDK5	S378	P383S	383	Missense	distal	5	no	18.836	18.849	EPSD	GDSC;CCLE	8.808	Up-regulation
CMGC_CDK_CDK5_CDK5_ST	Q96QB1	DLC1	Q00535	CDK5	T382	P383S	383	Missense	proximal	1	no	18.246	6.345	EPSD	GDSC;CCLE	8.808	Loss
CMGC_CDK_CDK5_CDK5_ST	Q96QB1	DLC1	Q00535	CDK5	T384	P383S	383	Missense	proximal	-1	no	10.132	10.133	EPSD	GDSC;CCLE	8.808	Up-regulation
CMGC_CDK_CDK5_CDK5_ST	Q96QB1	DLC1	Q00535	CDK5	T615	I622V	622	Missense	distal	7	no	17.849	17.852	EPSD	GDSC;CCLE	8.808	Up-regulation
CMGC_CDK_CDK5_CDK5_ST	Q96QB1	DLC1	Q00535	CDK5	S735	N736S	736	Missense	proximal	1	no	9.687	7.025	EPSD	GDSC;CCLE	8.808	Loss
CMGC_CDK_CDK5_CDK5_ST	Q96QB1	DLC1	Q00535	CDK5	T755	V759F	759	Missense	distal	4	no	17.881	17.788	EPSD	GDSC;CCLE	8.808	Down-regulation
CMGC_CDK_CDK5_CDK5_ST	Q96QB1	DLC1	Q00535	CDK5	S757	V759F	759	Missense	proximal	2	no	18.767	18.570	EPSD	GDSC;CCLE	8.808	Down-regulation
CMGC_CDK_CDK5_CDK5_ST	Q96QB1	DLC1	Q00535	CDK5	S859	N855S	855	Missense	distal	-4	no	17.929	18.441	EPSD;PhosphoSitePlus	GDSC;CCLE	8.808	Up-regulation
CMGC_CDK_CDK5_CDK5_ST	Q96QB1	DLC1	Q00535	CDK5	S946	L952V	952	Missense	distal	6	no	18.082	18.093	EPSD;PhosphoSitePlus	GDSC;CCLE	8.808	Up-regulation
CMGC_CDK_CDK5_CDK5_ST	Q96QB1	DLC1	Q00535	CDK5	S1291	P1287S	1287	Missense	distal	-4	no	10.935	11.282	EPSD	GDSC;CCLE	8.808	Up-regulation
CMGC_CDK_CDK5_CDK5_ST	Q96QB1	DLC1	Q00535	CDK5	S1291	R1292*	1292	Missense	proximal	1	no	10.935	-14.263	EPSD	GDSC	8.808	Loss
CMGC_CDK_CDK5_CDK5_ST	Q96QB1	DLC1	Q00535	CDK5	S1516	V1509I	1509	Missense	distal	-7	no	9.023	9.007	EPSD	GDSC	8.808	Down-regulation
CMGC_CDK_CDK5_CDK5_ST	Q96QB1	DLC1	Q00535	CDK5	S1516	R1512W	1512	Missense	distal	-4	no	9.023	8.675	EPSD	GDSC;CCLE	8.808	Loss
CMGC_CDK_CDK5_CDK5_ST	P30086	PEBP1	Q00535	CDK5	T44	P50A	50	Missense	distal	6	no	10.246	10.235	EPSD	GDSC;CCLE	8.808	Down-regulation
CMGC_CDK_CDK5_CDK5_ST	Q3V6T2	CCDC88A	Q00535	CDK5	S1837	A1841V	1841	Missense	distal	4	no	16.919	16.962	EPSD	GDSC	8.808	Up-regulation
CMGC_CDK_CDK5_CDK5_ST	P14416	DRD2	Q00535	CDK5	S19	N17K	17	Missense	proximal	-2	no	9.063	9.247	EPSD	GDSC;CCLE	8.808	Up-regulation
CMGC_CDK_CDK5_CDK5_ST	P14416	DRD2	Q00535	CDK5	S359	M358I	358	Missense	proximal	-1	no	10.442	10.446	EPSD	GDSC;CCLE	8.808	Up-regulation
CMGC_CDK_CDK5_CDK5_ST	P14416	DRD2	Q00535	CDK5	S359	R361W	361	Missense	proximal	2	no	10.442	10.250	EPSD	GDSC;CCLE	8.808	Down-regulation
CMGC_CDK_CDK5_CDK5_ST	Q13136	PPFIA1	Q00535	CDK5	T230	S232N	232	Missense	proximal	2	no	17.080	17.034	EPSD	GDSC	8.808	Down-regulation
CMGC_CDK_CDK5_CDK5_ST	Q13136	PPFIA1	Q00535	CDK5	S618	A625T	625	Missense	distal	7	no	18.198	18.206	EPSD	GDSC	8.808	Up-regulation
CMGC_CDK_CDK5_CDK5_ST	Q13136	PPFIA1	Q00535	CDK5	S693	R699C	699	Missense	distal	6	no	18.047	18.024	EPSD	GDSC;CCLE	8.808	Down-regulation
CMGC_CDK_CDK5_CDK5_ST	Q13136	PPFIA1	Q00535	CDK5	T701	R699C	699	Missense	proximal	-2	no	19.303	18.786	PhosphoSitePlus	GDSC;CCLE	8.808	Down-regulation
CMGC_CDK_CDK5_CDK5_ST	Q13136	PPFIA1	Q00535	CDK5	T701	S700P	700	Missense	proximal	-1	no	19.303	19.302	PhosphoSitePlus	GDSC;CCLE	8.808	Down-regulation
CMGC_CDK_CDK5_CDK5_ST	Q13136	PPFIA1	Q00535	CDK5	S708	R711W	711	Missense	distal	3	no	19.095	17.405	EPSD	GDSC;CCLE	8.808	Down-regulation
CMGC_CDK_CDK5_CDK5_ST	Q13136	PPFIA1	Q00535	CDK5	S741	S745T	745	Missense	distal	4	no	18.294	18.292	EPSD	GDSC;CCLE	8.808	Down-regulation
CMGC_CDK_CDK5_CDK5_ST	Q13136	PPFIA1	Q00535	CDK5	S744	S745T	745	Missense	proximal	1	no	7.992	9.406	EPSD	GDSC;CCLE	8.808	Gain
CMGC_CDK_CDK5_CDK5_ST	Q13136	PPFIA1	Q00535	CDK5	S953	A958T	958	Missense	distal	5	no	8.850	8.984	EPSD	GDSC;CCLE	8.808	Up-regulation
CMGC_CDK_CDK5_CDK5_ST	Q8IWU2	LMTK2	Q00535	CDK5	T90	A93V	93	Missense	distal	3	no	16.399	16.651	EPSD	GDSC;CCLE	8.808	Up-regulation
CMGC_CDK_CDK5_CDK5_ST	Q8IWU2	LMTK2	Q00535	CDK5	T90	T96P	96	Missense	distal	6	no	16.399	16.398	EPSD	GDSC;CCLE	8.808	Down-regulation
CMGC_CDK_CDK5_CDK5_ST	Q8IWU2	LMTK2	Q00535	CDK5	S587	L592F	592	Missense	distal	5	no	8.977	8.923	EPSD	GDSC;CCLE	8.808	Down-regulation
CMGC_CDK_CDK5_CDK5_ST	Q8IWU2	LMTK2	Q00535	CDK5	T825	R828Q	828	Missense	distal	3	no	18.282	16.479	EPSD	GDSC;CCLE	8.808	Down-regulation
CMGC_CDK_CDK5_CDK5_ST	Q8IWU2	LMTK2	Q00535	CDK5	S886	S890N	890	Missense	distal	4	no	17.602	17.571	EPSD	GDSC;CCLE	8.808	Down-regulation
CMGC_CDK_CDK5_CDK5_ST	Q8IWU2	LMTK2	Q00535	CDK5	S1124	E1119G	1119	Missense	distal	-5	no	17.619	17.623	EPSD	GDSC;CCLE	8.808	Up-regulation
CMGC_CDK_CDK5_CDK5_ST	Q8IWU2	LMTK2	Q00535	CDK5	S1397	P1391T	1391	Missense	distal	-6	no	17.537	17.548	EPSD	GDSC;CCLE	8.808	Up-regulation
CMGC_CDK_CDK5_CDK5_ST	Q8IWU2	LMTK2	Q00535	CDK5	S1450	A1455V	1455	Missense	distal	5	no	18.668	18.765	PhosphoSitePlus	GDSC;CCLE	8.808	Up-regulation
CMGC_CDK_CDK5_CDK5_ST	Q8IWU2	LMTK2	Q00535	CDK5	S1469	P1463S	1463	Missense	distal	-6	no	9.433	9.472	EPSD	GDSC;CCLE	8.808	Up-regulation
CMGC_CDK_CDK5_CDK5_ST	P47989	XDH	Q00535	CDK5	S399	L398P	398	Missense	proximal	-1	no	17.108	17.112	EPSD	GDSC;CCLE	8.808	Up-regulation
CMGC_CDK_CDK5_CDK5_ST	P47989	XDH	Q00535	CDK5	T804	S806G	806	Missense	proximal	2	no	8.916	8.843	EPSD	GDSC;CCLE	8.808	Down-regulation
CMGC_CDK_CDK5_CDK5_ST	P47989	XDH	Q00535	CDK5	T804	T807P	807	Missense	distal	3	no	8.916	8.380	EPSD	GDSC;CCLE	8.808	Loss
CMGC_CDK_CDK5_CDK5_ST	Q12778	FOXO1	Q00535	CDK5	S218	L219P	219	Missense	proximal	1	no	6.198	18.148	EPSD	GDSC;CCLE	8.808	Gain
CMGC_CDK_CDK5_CDK5_ST	Q12778	FOXO1	Q00535	CDK5	S329	T333A	333	Missense	distal	4	no	17.354	17.295	EPSD	GDSC;CCLE	8.808	Down-regulation
CMGC_CDK_CDK5_CDK5_ST	Q12778	FOXO1	Q00535	CDK5	S383	L381F	381	Missense	proximal	-2	no	17.450	17.207	EPSD	GDSC	8.808	Down-regulation
CMGC_CDK_CDK5_CDK5_ST	Q16643	DBN1	Q00535	CDK5	T377	P373S	373	Missense	distal	-4	no	8.934	9.280	EPSD	GDSC	8.808	Up-regulation
CMGC_CDK_CDK5_CDK5_ST	O43526	KCNQ2	Q00535	CDK5	S446	V443A	443	Missense	distal	-3	no	18.229	18.191	PhosphoSitePlus	GDSC;CCLE	8.808	Down-regulation
CMGC_CDK_CDK5_CDK5_ST	O43526	KCNQ2	Q00535	CDK5	S446	V450M	450	Missense	distal	4	no	18.229	18.153	PhosphoSitePlus	GDSC	8.808	Down-regulation
CMGC_CDK_CDK5_CDK5_ST	O43526	KCNQ2	Q00535	CDK5	S457	S457F	457	Missense	central	0	yes	17.610	0.000	EPSD	GDSC;CCLE	8.808	Loss
CMGC_CDK_CDK5_CDK5_ST	O43526	KCNQ2	Q00535	CDK5	S457	P458L	458	Missense	proximal	1	no	17.610	5.660	EPSD	GDSC	8.808	Loss
CMGC_CDK_CDK5_CDK5_ST	O43526	KCNQ2	Q00535	CDK5	S457	V450M	450	Missense	distal	-7	no	17.610	17.556	EPSD	GDSC	8.808	Down-regulation
CMGC_CDK_CDK5_CDK5_ST	O43526	KCNQ2	Q00535	CDK5	S466	S468R	468	Missense	proximal	2	no	17.733	17.832	EPSD	GDSC;CCLE	8.808	Up-regulation
CMGC_CDK_CDK5_CDK5_ST	O43526	KCNQ2	Q00535	CDK5	S503	R497H	497	Missense	distal	-6	no	8.905	8.839	EPSD	GDSC;CCLE	8.808	Down-regulation
CMGC_CDK_CDK5_CDK5_ST	Q9UM11	FZR1	Q00535	CDK5	S36	S40L	40	Missense	distal	4	no	17.598	17.515	EPSD	GDSC;CCLE	8.808	Down-regulation
CMGC_CDK_CDK5_CDK5_ST	Q9UM11	FZR1	Q00535	CDK5	S40	S40L	40	Missense	central	0	yes	19.875	0.000	PhosphoSitePlus;EPSD	GDSC;CCLE	8.808	Loss
CMGC_CDK_CDK5_CDK5_ST	P12931	SRC	Q00535	CDK5	S219	Q222H	222	Missense	distal	3	no	8.336	9.119	EPSD	GDSC;CCLE	8.808	Gain
CMGC_CDK_CDK5_CDK5_ST	P15927	RPA2	Q00535	CDK5	S72	E70K	70	Missense	proximal	-2	no	9.145	9.559	EPSD	GDSC;CCLE	8.808	Up-regulation
CMGC_CDK_CDK5_CDK5_ST	O14939	PLD2	Q00535	CDK5	S134	R137*	137	Missense	distal	3	no	18.193	14.811	PhosphoSitePlus	GDSC	8.808	Down-regulation
CMGC_CDK_CDK5_CDK5_ST	O14939	PLD2	Q00535	CDK5	S134	A130D	130	Missense	distal	-4	no	18.193	18.419	PhosphoSitePlus	GDSC	8.808	Up-regulation
CMGC_CDK_CDK5_CDK5_ST	O14939	PLD2	Q00535	CDK5	S134	N141S	141	Missense	distal	7	no	18.193	18.198	PhosphoSitePlus	GDSC	8.808	Up-regulation
CMGC_CDK_CDK5_CDK5_ST	O14939	PLD2	Q00535	CDK5	S134	R128*	128	Missense	distal	-6	no	18.193	17.906	PhosphoSitePlus	GDSC	8.808	Down-regulation
CMGC_CDK_CDK5_CDK5_ST	O14939	PLD2	Q00535	CDK5	S484	P487T	487	Missense	distal	3	no	10.070	10.606	EPSD	GDSC;CCLE	8.808	Up-regulation
CMGC_CDK_CDK5_CDK5_ST	O14939	PLD2	Q00535	CDK5	S493	P487T	487	Missense	distal	-6	no	19.277	19.288	EPSD	GDSC;CCLE	8.808	Up-regulation
CMGC_CDK_CDK5_CDK5_ST	O14939	PLD2	Q00535	CDK5	T575	Y580*	580	Missense	distal	5	no	16.231	16.009	EPSD	GDSC	8.808	Down-regulation
CMGC_CDK_CDK5_CDK5_ST	Q05397	PTK2	Q00535	CDK5	T13	N15S	15	Missense	proximal	2	no	18.075	18.121	EPSD	GDSC	8.808	Up-regulation
CMGC_CDK_CDK5_CDK5_ST	Q05397	PTK2	Q00535	CDK5	S17	N15S	15	Missense	proximal	-2	no	9.267	9.380	EPSD	GDSC	8.808	Up-regulation
CMGC_CDK_CDK5_CDK5_ST	Q05397	PTK2	Q00535	CDK5	S732	P731S	731	Missense	proximal	-1	no	17.875	17.877	EPSD	GDSC;CCLE	8.808	Up-regulation
CMGC_CDK_CDK5_CDK5_ST	Q05397	PTK2	Q00535	CDK5	S732	P733T	733	Missense	proximal	1	no	17.875	7.388	EPSD	GDSC;CCLE	8.808	Loss
CMGC_CDK_CDK5_CDK5_ST	Q05397	PTK2	Q00535	CDK5	S893	S887N	887	Missense	distal	-6	no	16.233	16.175	EPSD	GDSC	8.808	Down-regulation
CMGC_CDK_CDK5_CDK5_ST	O94811	TPPP	Q00535	CDK5	S45	G39S	39	Missense	distal	-6	no	15.499	15.594	EPSD	GDSC	8.808	Up-regulation
CMGC_CDK_CDK5_CDK5_ST	O94811	TPPP	Q00535	CDK5	S160	R165S	165	Missense	distal	5	no	18.510	18.447	PhosphoSitePlus;EPSD	GDSC;CCLE	8.808	Down-regulation
CMGC_CDK_CDK5_CDK5_ST	O94811	TPPP	Q00535	CDK5	S164	R165S	165	Missense	proximal	1	no	9.997	7.043	EPSD	GDSC;CCLE	8.808	Loss
CMGC_CDK_CDK5_CDK5_ST	P37231	PPARG	Q00535	CDK5	S112	S112C	112	Missense	central	0	yes	17.396	0.000	EPSD	GDSC;CCLE	8.808	Loss
CMGC_CDK_CDK5_CDK5_ST	P04637	TP53	Q00535	CDK5	S33	Q38*	38	Missense	distal	5	no	17.666	17.329	EPSD;PhosphoSitePlus	GDSC	8.808	Down-regulation
CMGC_CDK_CDK5_CDK5_ST	P04637	TP53	Q00535	CDK5	T81	A74S	74	Missense	distal	-7	no	16.829	16.883	EPSD	GDSC;CCLE	8.808	Up-regulation
CMGC_CDK_CDK5_CDK5_ST	P04637	TP53	Q00535	CDK5	S99	K101*	101	Missense	proximal	2	no	10.461	9.948	EPSD	GDSC	8.808	Down-regulation
CMGC_CDK_CDK5_CDK5_ST	P04637	TP53	Q00535	CDK5	S99	Q100*	100	Missense	proximal	1	no	10.461	-14.708	EPSD	GDSC	8.808	Loss
CMGC_CDK_CDK5_CDK5_ST	P04637	TP53	Q00535	CDK5	S99	S94*	94	Missense	distal	-5	no	10.461	9.898	EPSD	GDSC	8.808	Down-regulation
CMGC_CDK_CDK5_CDK5_ST	P04637	TP53	Q00535	CDK5	S127	Y126*	126	Missense	proximal	-1	no	16.799	16.792	EPSD	GDSC	8.808	Down-regulation
CMGC_CDK_CDK5_CDK5_ST	P04637	TP53	Q00535	CDK5	S127	K120*	120	Missense	distal	-7	no	16.799	16.641	EPSD	GDSC	8.808	Down-regulation
CMGC_CDK_CDK5_CDK5_ST	P04637	TP53	Q00535	CDK5	T150	Q144*	144	Missense	distal	-6	no	16.442	16.212	EPSD	GDSC	8.808	Down-regulation
CMGC_CDK_CDK5_CDK5_ST	P04637	TP53	Q00535	CDK5	T150	W146*	146	Missense	distal	-4	no	16.442	15.512	EPSD	GDSC	8.808	Down-regulation
CMGC_CDK_CDK5_CDK5_ST	P04637	TP53	Q00535	CDK5	S315	Q317*	317	Missense	proximal	2	no	18.385	18.060	EPSD	GDSC	8.808	Down-regulation
CMGC_CDK_CDK5_CDK5_ST	P04637	TP53	Q00535	CDK5	S315	K319*	319	Missense	distal	4	no	18.385	18.136	EPSD	GDSC	8.808	Down-regulation
CMGC_CDK_CDK5_CDK5_ST	P04637	TP53	Q00535	CDK5	S362	G360V	360	Missense	proximal	-2	no	9.264	9.548	EPSD	GDSC;CCLE	8.808	Up-regulation
CMGC_CDK_CDK5_CDK5_ST	Q99490	AGAP2	Q00535	CDK5	S267	A260D	260	Missense	distal	-7	no	20.291	20.302	EPSD	GDSC	8.808	Up-regulation
CMGC_CDK_CDK5_CDK5_ST	Q99490	AGAP2	Q00535	CDK5	S267	P268H	268	Missense	proximal	1	no	20.291	1.779	EPSD	GDSC;CCLE	8.808	Loss
CMGC_CDK_CDK5_CDK5_ST	Q99490	AGAP2	Q00535	CDK5	S523	R525G	525	Missense	proximal	2	no	18.242	18.069	EPSD	GDSC;CCLE	8.808	Down-regulation
CMGC_CDK_CDK5_CDK5_ST	Q99490	AGAP2	Q00535	CDK5	S615	L612V	612	Missense	distal	-3	no	18.478	18.524	EPSD	GDSC;CCLE	8.808	Up-regulation
CMGC_CDK_CDK5_CDK5_ST	Q99490	AGAP2	Q00535	CDK5	T635	S638F	638	Missense	distal	3	no	16.338	15.160	EPSD	GDSC;CCLE	8.808	Down-regulation
CMGC_CDK_CDK5_CDK5_ST	Q99490	AGAP2	Q00535	CDK5	T812	P819H	819	Missense	distal	7	no	16.822	16.818	EPSD	GDSC;CCLE	8.808	Down-regulation
CMGC_CDK_CDK5_CDK5_ST	Q99490	AGAP2	Q00535	CDK5	S818	P819H	819	Missense	proximal	1	no	17.622	-0.891	EPSD	GDSC;CCLE	8.808	Loss
CMGC_CDK_CDK5_CDK5_ST	Q99490	AGAP2	Q00535	CDK5	S827	P826S	826	Missense	proximal	-1	no	18.771	18.773	EPSD	GDSC;CCLE	8.808	Up-regulation
CMGC_CDK_CDK5_CDK5_ST	P35612	ADD2	Q00535	CDK5	S60	P61L	61	Missense	proximal	1	no	15.928	3.979	EPSD	GDSC	8.808	Loss
CMGC_CDK_CDK5_CDK5_ST	P35612	ADD2	Q00535	CDK5	T436	V443D	443	Missense	distal	7	no	17.896	17.890	EPSD	GDSC;CCLE	8.808	Down-regulation
CMGC_CDK_CDK5_CDK5_ST	P35612	ADD2	Q00535	CDK5	S455	P456S	456	Missense	proximal	1	no	17.512	5.611	EPSD	GDSC;CCLE	8.808	Loss
CMGC_CDK_CDK5_CDK5_ST	P35612	ADD2	Q00535	CDK5	S667	S667N	667	Missense	central	0	yes	9.069	0.000	EPSD	GDSC;CCLE	8.808	Loss
CMGC_CDK_CDK5_CDK5_ST	P35612	ADD2	Q00535	CDK5	T711	R710Q	710	Missense	proximal	-1	no	17.101	17.100	EPSD	GDSC;CCLE	8.808	Down-regulation
CMGC_CDK_CDK5_CDK5_ST	O00429	DNM1L	Q00535	CDK5	S136	P137T	137	Missense	proximal	1	no	17.605	7.118	EPSD	GDSC	8.808	Loss
CMGC_CDK_CDK5_CDK5_ST	O00429	DNM1L	Q00535	CDK5	S136	V139I	139	Missense	distal	3	no	17.605	17.157	EPSD	GDSC	8.808	Down-regulation
CMGC_CDK_CDK5_CDK5_ST	O00429	DNM1L	Q00535	CDK5	S529	E523*	523	Missense	distal	-6	no	11.576	11.382	EPSD	GDSC	8.808	Down-regulation
CMGC_CDK_CDK5_CDK5_ST	O00429	DNM1L	Q00535	CDK5	S548	A551T	551	Missense	distal	3	no	17.721	18.502	EPSD	GDSC;CCLE	8.808	Up-regulation
CMGC_CDK_CDK5_CDK5_ST	O00429	DNM1L	Q00535	CDK5	S548	P547L	547	Missense	proximal	-1	no	17.721	17.716	EPSD	GDSC	8.808	Down-regulation
CMGC_CDK_CDK5_CDK5_ST	O00429	DNM1L	Q00535	CDK5	S548	A550D	550	Missense	proximal	2	no	17.721	17.709	EPSD	GDSC	8.808	Down-regulation
CMGC_CDK_CDK5_CDK5_ST	Q8IV63	VRK3	Q00535	CDK5	S59	P60S	60	Missense	proximal	1	no	20.284	8.383	EPSD	GDSC;CCLE	8.808	Loss
CMGC_CDK_CDK5_CDK5_ST	Q8IV63	VRK3	Q00535	CDK5	S59	S54Y	54	Missense	distal	-5	no	20.284	20.034	EPSD	GDSC;CCLE	8.808	Down-regulation
CMGC_CDK_CDK5_CDK5_ST	Q8IV63	VRK3	Q00535	CDK5	S71	S78*	78	Missense	distal	7	no	17.408	17.379	EPSD	GDSC	8.808	Down-regulation
CMGC_CDK_CDK5_CDK5_ST	Q8IV63	VRK3	Q00535	CDK5	S122	K125M	125	Missense	distal	3	no	19.149	16.470	EPSD	GDSC	8.808	Down-regulation
CMGC_CDK_CDK5_CDK5_ST	Q8IV63	VRK3	Q00535	CDK5	S122	C128Y	128	Missense	distal	6	no	19.149	19.151	EPSD	GDSC	8.808	Up-regulation
CMGC_CDK_CDK5_CDK5_ST	Q8IV63	VRK3	Q00535	CDK5	S122	C128W	128	Missense	distal	6	no	19.149	19.155	EPSD	GDSC	8.808	Up-regulation
CMGC_CDK_CDK5_CDK5_ST	Q8IV63	VRK3	Q00535	CDK5	S122	C128R	128	Missense	distal	6	no	19.149	19.172	EPSD	GDSC	8.808	Up-regulation
CMGC_CDK_CDK5_CDK5_ST	Q8IV63	VRK3	Q00535	CDK5	S127	C128R	128	Missense	proximal	1	no	-2.293	9.434	EPSD	GDSC	8.808	Gain
CMGC_CDK_CDK5_CDK5_ST	Q8IV63	VRK3	Q00535	CDK5	S129	K125M	125	Missense	distal	-4	no	19.829	18.885	EPSD	GDSC	8.808	Down-regulation
CMGC_CDK_CDK5_CDK5_ST	Q8IV63	VRK3	Q00535	CDK5	S129	C128Y	128	Missense	proximal	-1	no	19.829	19.830	EPSD	GDSC	8.808	Up-regulation
CMGC_CDK_CDK5_CDK5_ST	Q8IV63	VRK3	Q00535	CDK5	S129	C128W	128	Missense	proximal	-1	no	19.829	19.831	EPSD	GDSC	8.808	Up-regulation
CMGC_CDK_CDK5_CDK5_ST	Q8IV63	VRK3	Q00535	CDK5	S129	C128R	128	Missense	proximal	-1	no	19.829	19.835	EPSD	GDSC	8.808	Up-regulation
CMGC_CDK_CDK5_CDK5_ST	Q8IV63	VRK3	Q00535	CDK5	S348	A341S	341	Missense	distal	-7	no	17.815	17.869	EPSD	GDSC	8.808	Up-regulation
CMGC_CDK_CDK5_CDK5_ST	Q16665	HIF1A	Q00535	CDK5	S28	S28Y	28	Missense	central	0	yes	9.582	0.000	EPSD	GDSC	8.808	Loss
CMGC_CDK_CDK5_CDK5_ST	Q16665	HIF1A	Q00535	CDK5	T458	R463*	463	Missense	distal	5	no	17.591	17.129	EPSD	GDSC	8.808	Down-regulation
CMGC_CDK_CDK5_CDK5_ST	Q16665	HIF1A	Q00535	CDK5	T458	S465T	465	Missense	distal	7	no	17.591	17.589	EPSD	GDSC;CCLE	8.808	Down-regulation
CMGC_CDK_CDK5_CDK5_ST	Q16665	HIF1A	Q00535	CDK5	S510	Q508*	508	Missense	proximal	-2	no	18.561	17.672	EPSD	GDSC	8.808	Down-regulation
CMGC_CDK_CDK5_CDK5_ST	Q16665	HIF1A	Q00535	CDK5	S515	Q508*	508	Missense	distal	-7	no	17.825	17.704	EPSD	GDSC	8.808	Down-regulation
CMGC_CDK_CDK5_CDK5_ST	Q16665	HIF1A	Q00535	CDK5	S589	A593P	593	Missense	distal	4	no	18.794	18.854	EPSD	GDSC;CCLE	8.808	Up-regulation
CMGC_CDK_CDK5_CDK5_ST	Q16665	HIF1A	Q00535	CDK5	S657	Y659N	659	Missense	proximal	2	no	19.398	19.503	EPSD	GDSC;CCLE	8.808	Up-regulation
CMGC_CDK_CDK5_CDK5_ST	Q16665	HIF1A	Q00535	CDK5	S668	K674N	674	Missense	distal	6	no	19.370	19.356	EPSD	GDSC;CCLE	8.808	Down-regulation
CMGC_CDK_CDK5_CDK5_ST	Q16665	HIF1A	Q00535	CDK5	S687	P685S	685	Missense	proximal	-2	no	18.717	18.619	PhosphoSitePlus	GDSC;CCLE	8.808	Down-regulation
CMGC_CDK_CDK5_CDK5_ST	P07196	NEFL	Q00535	CDK5	S435	T436P	436	Missense	proximal	1	no	7.799	18.287	EPSD	GDSC	8.808	Gain
CMGC_CDK_CDK5_CDK5_ST	Q15717	ELAVL1	Q00535	CDK5	S146	V149I	149	Missense	distal	3	no	8.850	8.402	EPSD	GDSC;CCLE	8.808	Loss
CMGC_CDK_CDK5_CDK5_ST	Q15717	ELAVL1	Q00535	CDK5	S202	S197L	197	Missense	distal	-5	no	19.114	18.894	PhosphoSitePlus	GDSC;CCLE	8.808	Down-regulation
CMGC_CDK_CDK5_CDK5_ST	Q14814	MEF2D	Q00535	CDK5	S98	K91Q	91	Missense	distal	-7	no	16.728	16.690	EPSD	GDSC	8.808	Down-regulation
CMGC_CDK_CDK5_CDK5_ST	Q14814	MEF2D	Q00535	CDK5	S98	K91N	91	Missense	distal	-7	no	16.728	16.685	EPSD	GDSC	8.808	Down-regulation
CMGC_CDK_CDK5_CDK5_ST	Q14814	MEF2D	Q00535	CDK5	S98	G95C	95	Missense	distal	-3	no	16.728	16.705	EPSD	GDSC;CCLE	8.808	Down-regulation
CMGC_CDK_CDK5_CDK5_ST	Q14814	MEF2D	Q00535	CDK5	S110	Q109K	109	Missense	proximal	-1	no	16.893	16.897	EPSD	GDSC	8.808	Up-regulation
CMGC_CDK_CDK5_CDK5_ST	Q14814	MEF2D	Q00535	CDK5	S251	P254L	254	Missense	distal	3	no	17.827	16.755	EPSD	GDSC;CCLE	8.808	Down-regulation
CMGC_CDK_CDK5_CDK5_ST	Q14814	MEF2D	Q00535	CDK5	S258	T259P	259	Missense	proximal	1	no	7.179	17.667	EPSD	GDSC	8.808	Gain
CMGC_CDK_CDK5_CDK5_ST	Q14814	MEF2D	Q00535	CDK5	S444	R449H	449	Missense	distal	5	no	20.530	20.427	PhosphoSitePlus	GDSC;CCLE	8.808	Down-regulation
CMGC_CDK_CDK5_CDK5_ST	Q14814	MEF2D	Q00535	CDK5	S444	S444P	444	Missense	central	0	yes	20.530	0.000	PhosphoSitePlus	GDSC	8.808	Loss
CMGC_CDK_CDK5_CDK5_ST	Q14814	MEF2D	Q00535	CDK5	S444	P445Q	445	Missense	proximal	1	no	20.530	11.554	PhosphoSitePlus	GDSC	8.808	Down-regulation
CMGC_CDK_CDK5_CDK5_ST	Q14814	MEF2D	Q00535	CDK5	S446	R449H	449	Missense	distal	3	no	10.776	9.757	EPSD	GDSC;CCLE	8.808	Down-regulation
CMGC_CDK_CDK5_CDK5_ST	Q14814	MEF2D	Q00535	CDK5	S446	S444P	444	Missense	proximal	-2	no	10.776	10.875	EPSD	GDSC	8.808	Up-regulation
CMGC_CDK_CDK5_CDK5_ST	Q14814	MEF2D	Q00535	CDK5	S446	P445Q	445	Missense	proximal	-1	no	10.776	10.775	EPSD	GDSC	8.808	Down-regulation
CMGC_CDK_CDK5_CDK5_ST	Q14814	MEF2D	Q00535	CDK5	S450	R449H	449	Missense	proximal	-1	no	18.610	18.607	EPSD	GDSC;CCLE	8.808	Down-regulation
CMGC_CDK_CDK5_CDK5_ST	Q14814	MEF2D	Q00535	CDK5	S450	S444P	444	Missense	distal	-6	no	18.610	18.571	EPSD	GDSC	8.808	Down-regulation
CMGC_CDK_CDK5_CDK5_ST	Q14814	MEF2D	Q00535	CDK5	S450	P445Q	445	Missense	distal	-5	no	18.610	18.552	EPSD	GDSC	8.808	Down-regulation
CMGC_CDK_CDK5_CDK5_ST	Q14814	MEF2D	Q00535	CDK5	S472	G475R	475	Missense	distal	3	no	16.962	18.344	EPSD	GDSC	8.808	Up-regulation
CMGC_CDK_CDK5_CDK5_ST	Q96KR7	PHACTR3	Q00535	CDK5	T45	T45R	45	Missense	central	0	yes	15.997	0.000	EPSD	GDSC;CCLE	8.808	Loss
CMGC_CDK_CDK5_CDK5_ST	Q96KR7	PHACTR3	Q00535	CDK5	T45	E41A	41	Missense	distal	-4	no	15.997	15.723	EPSD	GDSC;CCLE	8.808	Down-regulation
CMGC_CDK_CDK5_CDK5_ST	Q96KR7	PHACTR3	Q00535	CDK5	S156	S149L	149	Missense	distal	-7	no	17.190	17.134	EPSD	GDSC;CCLE	8.808	Down-regulation
CMGC_CDK_CDK5_CDK5_ST	Q96KR7	PHACTR3	Q00535	CDK5	S230	V225M	225	Missense	distal	-5	no	16.683	16.457	EPSD	GDSC	8.808	Down-regulation
CMGC_CDK_CDK5_CDK5_ST	Q96KR7	PHACTR3	Q00535	CDK5	T274	G270D	270	Missense	distal	-4	no	16.467	16.632	EPSD	GDSC	8.808	Up-regulation
CMGC_CDK_CDK5_CDK5_ST	Q96KR7	PHACTR3	Q00535	CDK5	T274	L272H	272	Missense	proximal	-2	no	16.467	16.566	EPSD	GDSC;CCLE	8.808	Up-regulation
CMGC_CDK_CDK5_CDK5_ST	Q96KR7	PHACTR3	Q00535	CDK5	S278	L272H	272	Missense	distal	-6	no	17.242	17.305	EPSD	GDSC;CCLE	8.808	Up-regulation
CMGC_CDK_CDK5_CDK5_ST	Q96KR7	PHACTR3	Q00535	CDK5	S318	V325A	325	Missense	distal	7	no	19.725	19.717	PhosphoSitePlus	GDSC;CCLE	8.808	Down-regulation
CMGC_CDK_CDK5_CDK5_ST	Q96KR7	PHACTR3	Q00535	CDK5	S328	V325A	325	Missense	distal	-3	no	9.417	9.379	EPSD	GDSC;CCLE	8.808	Down-regulation
CMGC_CDK_CDK5_CDK5_ST	Q14195	DPYSL3	Q00535	CDK5	S472	C471*	471	Missense	proximal	-1	no	17.452	17.446	EPSD	GDSC	8.808	Down-regulation
CMGC_CDK_CDK5_CDK5_ST	Q14195	DPYSL3	Q00535	CDK5	S564	S568Y	568	Missense	distal	4	no	9.910	9.825	EPSD	GDSC;CCLE	8.808	Down-regulation
CMGC_CDK_CDK5_CDK5_ST	Q16555	DPYSL2	Q00535	CDK5	S522	Q526*	526	Missense	distal	4	no	20.593	20.438	PhosphoSitePlus	GDSC	8.808	Down-regulation
CMGC_CDK_CDK5_CDK5_ST	P27695	APEX1	Q00535	CDK5	S54	P48T	48	Missense	distal	-6	no	17.662	17.673	EPSD	GDSC;CCLE	8.808	Up-regulation
CMGC_CDK_CDK5_CDK5_ST	P27695	APEX1	Q00535	CDK5	T233	Q235*	235	Missense	proximal	2	no	17.263	16.938	PhosphoSitePlus	GDSC	8.808	Down-regulation
CMGC_CDK_CDK5_CDK5_ST	P06400	RB1	Q00535	CDK5	S567	W563*	563	Missense	distal	-4	no	16.330	15.400	EPSD	GDSC	8.808	Down-regulation
CMGC_CDK_CDK5_CDK5_ST	P06400	RB1	Q00535	CDK5	S567	S567*	567	Missense	central	0	yes	16.330	0.000	EPSD	GDSC	8.808	Loss
CMGC_CDK_CDK5_CDK5_ST	P06400	RB1	Q00535	CDK5	S608	T601S	601	Missense	distal	-7	no	18.641	18.656	EPSD	GDSC;CCLE	8.808	Up-regulation
CMGC_CDK_CDK5_CDK5_ST	P06400	RB1	Q00535	CDK5	S780	R787*	787	Missense	distal	7	no	18.526	18.495	EPSD	GDSC	8.808	Down-regulation
CMGC_CDK_CDK5_CDK5_ST	P06400	RB1	Q00535	CDK5	S788	R787*	787	Missense	proximal	-1	no	19.412	19.399	EPSD	GDSC	8.808	Down-regulation
CMGC_CDK_CDK5_CDK5_ST	P06400	RB1	Q00535	CDK5	S795	G801*	801	Missense	distal	6	no	19.344	19.319	PhosphoSitePlus;EPSD	GDSC	8.808	Down-regulation
CMGC_CDK_CDK5_CDK5_ST	P06400	RB1	Q00535	CDK5	S807	G801*	801	Missense	distal	-6	no	19.364	19.178	EPSD;PhosphoSitePlus	GDSC	8.808	Down-regulation
CMGC_CDK_CDK5_CDK5_ST	P06400	RB1	Q00535	CDK5	T821	L819V	819	Missense	proximal	-2	no	18.599	18.832	EPSD	GDSC;CCLE	8.808	Up-regulation
CMGC_CDK_CDK5_CDK5_ST	P06400	RB1	Q00535	CDK5	T826	L819V	819	Missense	distal	-7	no	17.199	17.237	EPSD	GDSC;CCLE	8.808	Up-regulation
CMGC_CDK_CDK5_CDK5_ST	Q16236	NFE2L2	Q00535	CDK5	S408	P409S	409	Missense	proximal	1	no	17.464	5.563	EPSD	GDSC;CCLE	8.808	Loss
CMGC_CDK_CDK5_CDK5_ST	P35968	KDR	Q00535	CDK5	S229	P230S	230	Missense	proximal	1	no	18.514	6.613	PhosphoSitePlus	GDSC;CCLE	8.808	Loss
CMGC_CDK_CDK5_CDK5_ST	P35968	KDR	Q00535	CDK5	S1231	R1232Q	1232	Missense	proximal	1	no	10.206	10.177	EPSD	GDSC;CCLE	8.808	Down-regulation
CMGC_CDK_CDK5_CDK5_ST	P35222	CTNNB1	Q00535	CDK5	T289	K292N	292	Missense	distal	3	no	9.190	7.257	EPSD	GDSC;CCLE	8.808	Loss
CMGC_CDK_CDK5_CDK5_ST	P35222	CTNNB1	Q00535	CDK5	T547	R549H	549	Missense	proximal	2	no	10.356	10.241	EPSD	GDSC;CCLE	8.808	Down-regulation
CMGC_CDK_CDK5_CDK5_ST	Q9UKV5	AMFR	Q00535	CDK5	S542	R536C	536	Missense	distal	-6	no	17.031	16.878	EPSD	GDSC;CCLE	8.808	Down-regulation
CMGC_CDK_CDK5_CDK5_ST	P40763	STAT3	Q00535	CDK5	T714	C712Y	712	Missense	proximal	-2	no	17.499	17.542	EPSD	GDSC;CCLE	8.808	Up-regulation
CMGC_CDK_CDK5_CDK5_ST	Q05193	DNM1	Q00535	CDK5	S116	N121S	121	Missense	distal	5	no	17.961	18.025	EPSD	GDSC;CCLE	8.808	Up-regulation
CMGC_CDK_CDK5_CDK5_ST	Q05193	DNM1	Q00535	CDK5	S126	N121S	121	Missense	distal	-5	no	18.047	18.139	EPSD	GDSC;CCLE	8.808	Up-regulation
CMGC_CDK_CDK5_CDK5_ST	Q05193	DNM1	Q00535	CDK5	S774	R772H	772	Missense	proximal	-2	no	17.473	17.212	EPSD	GDSC;CCLE	8.808	Down-regulation
CMGC_CDK_CDK5_CDK5_ST	Q05193	DNM1	Q00535	CDK5	S778	R772H	772	Missense	distal	-6	no	18.092	18.026	EPSD	GDSC;CCLE	8.808	Down-regulation
CMGC_CDK_CDK5_CDK5_ST	Q05193	DNM1	Q00535	CDK5	S857	D863Y	863	Missense	distal	6	no	19.199	19.195	EPSD	GDSC;CCLE	8.808	Down-regulation
CMGC_CDK_CDK5_CDK5_ST	Q96C19	EFHD2	Q00535	CDK5	S74	P72S	72	Missense	proximal	-2	no	19.393	19.295	PhosphoSitePlus	GDSC;CCLE	8.808	Down-regulation
CMGC_CDK_CDK5_CDK5_ST	Q96C19	EFHD2	Q00535	CDK5	S76	P72S	72	Missense	distal	-4	no	9.599	9.945	EPSD	GDSC;CCLE	8.808	Up-regulation
CMGC_CDK_CDK5_CDK5_ST	Q02078	MEF2A	Q00535	CDK5	T108	P109T	109	Missense	proximal	1	no	17.738	7.251	EPSD	GDSC	8.808	Loss
CMGC_CDK_CDK5_CDK5_ST	Q02078	MEF2A	Q00535	CDK5	S255	M251I	251	Missense	distal	-4	no	17.774	18.228	EPSD	GDSC	8.808	Up-regulation
CMGC_CDK_CDK5_CDK5_ST	Q02078	MEF2A	Q00535	CDK5	S268	N263S	263	Missense	distal	-5	no	8.963	9.055	EPSD	GDSC	8.808	Up-regulation
CMGC_CDK_CDK5_CDK5_ST	Q02078	MEF2A	Q00535	CDK5	S268	R274*	274	Missense	distal	6	no	8.963	8.921	EPSD	GDSC	8.808	Down-regulation
CMGC_CDK_CDK5_CDK5_ST	O43464	HTRA2	Q00535	CDK5	T101	R104G	104	Missense	distal	3	no	10.050	8.668	EPSD	GDSC;CCLE	8.808	Loss
CMGC_CDK_CDK5_CDK5_ST	P29474	NOS3	Q00535	CDK5	S53	A49V	49	Missense	distal	-4	no	17.923	18.342	EPSD	GDSC;CCLE	8.808	Up-regulation
CMGC_CDK_CDK5_CDK5_ST	P29474	NOS3	Q00535	CDK5	S57	E64V	64	Missense	distal	7	no	19.339	19.345	EPSD	GDSC;CCLE	8.808	Up-regulation
CMGC_CDK_CDK5_CDK5_ST	P29474	NOS3	Q00535	CDK5	T60	E64V	64	Missense	distal	4	no	9.456	9.489	EPSD	GDSC;CCLE	8.808	Up-regulation
CMGC_CDK_CDK5_CDK5_ST	P29474	NOS3	Q00535	CDK5	S114	S114F	114	Missense	central	0	yes	17.821	0.000	PhosphoSitePlus	GDSC;CCLE	8.808	Loss
CMGC_CDK_CDK5_CDK5_ST	P29474	NOS3	Q00535	CDK5	S114	G116S	116	Missense	proximal	2	no	17.821	17.894	PhosphoSitePlus	GDSC	8.808	Up-regulation
CMGC_CDK_CDK5_CDK5_ST	P29474	NOS3	Q00535	CDK5	S600	N598I	598	Missense	proximal	-2	no	17.366	17.257	EPSD	GDSC;CCLE	8.808	Down-regulation
CMGC_CDK_CDK5_CDK5_ST	P29474	NOS3	Q00535	CDK5	S725	R721G	721	Missense	distal	-4	no	20.256	19.876	EPSD	GDSC;CCLE	8.808	Down-regulation
CMGC_CDK_CDK5_CDK5_ST	P29474	NOS3	Q00535	CDK5	S836	G843R	843	Missense	distal	7	no	18.240	18.251	EPSD	GDSC;CCLE	8.808	Up-regulation
CMGC_CDK_CDK5_CDK5_ST	Q13315	ATM	Q00535	CDK5	S794	L787F	787	Missense	distal	-7	no	19.473	19.445	PhosphoSitePlus	GDSC;CCLE	8.808	Down-regulation
CMGC_CDK_CDK5_CDK5_ST	Q13315	ATM	Q00535	CDK5	S1105	K1101E	1101	Missense	distal	-4	no	9.089	8.586	EPSD	GDSC;CCLE	8.808	Loss
CMGC_CDK_CDK5_CDK5_ST	Q13315	ATM	Q00535	CDK5	S1878	H1876Q	1876	Missense	proximal	-2	no	8.745	8.870	EPSD	GDSC;CCLE	8.808	Gain
CMGC_CDK_CDK5_CDK5_ST	Q9UQL6	HDAC5	Q00535	CDK5	S3	S7L	7	Missense	distal	4	no	16.820	16.737	EPSD	GDSC	8.808	Down-regulation
CMGC_CDK_CDK5_CDK5_ST	Q9UQL6	HDAC5	Q00535	CDK5	S1108	E1114Q	1114	Missense	distal	6	no	17.888	17.894	EPSD	GDSC	8.808	Up-regulation
CMGC_CDK_CDK5_CDK5_ST	Q5S007	LRRK2	Q00535	CDK5	T213	F215V	215	Missense	proximal	2	no	9.203	9.399	EPSD	GDSC	8.808	Up-regulation
CMGC_CDK_CDK5_CDK5_ST	Q5S007	LRRK2	Q00535	CDK5	T213	S210N	210	Missense	distal	-3	no	9.203	9.185	EPSD	GDSC;CCLE	8.808	Down-regulation
CMGC_CDK_CDK5_CDK5_ST	Q5S007	LRRK2	Q00535	CDK5	S962	K963Q	963	Missense	proximal	1	no	0.155	9.357	EPSD	GDSC	8.808	Gain
CMGC_CDK_CDK5_CDK5_ST	Q5S007	LRRK2	Q00535	CDK5	S1445	G1451A	1451	Missense	distal	6	no	17.728	17.726	EPSD	GDSC;CCLE	8.808	Down-regulation
CMGC_CDK_CDK5_CDK5_ST	Q5S007	LRRK2	Q00535	CDK5	S1445	T1452I	1452	Missense	distal	7	no	17.728	17.723	EPSD	GDSC;CCLE	8.808	Down-regulation
CMGC_CDK_CDK5_CDK5_ST	Q5S007	LRRK2	Q00535	CDK5	S1445	A1440P	1440	Missense	distal	-5	no	17.728	17.887	EPSD	GDSC	8.808	Up-regulation
CMGC_CDK_CDK5_CDK5_ST	Q5S007	LRRK2	Q00535	CDK5	S1457	G1451A	1451	Missense	distal	-6	no	9.176	9.157	EPSD	GDSC;CCLE	8.808	Down-regulation
CMGC_CDK_CDK5_CDK5_ST	Q5S007	LRRK2	Q00535	CDK5	S1457	T1452I	1452	Missense	distal	-5	no	9.176	9.069	EPSD	GDSC;CCLE	8.808	Down-regulation
CMGC_CDK_CDK5_CDK5_ST	Q5S007	LRRK2	Q00535	CDK5	S1457	V1456A	1456	Missense	proximal	-1	no	9.176	9.172	EPSD	GDSC;CCLE	8.808	Down-regulation
CMGC_CDK_CDK5_CDK5_ST	O15169	AXIN1	Q00535	CDK5	S166	F167V	167	Missense	proximal	1	no	-1.981	9.088	EPSD	GDSC;CCLE	8.808	Gain
CMGC_CDK_CDK5_CDK5_ST	O15169	AXIN1	Q00535	CDK5	S217	Y210H	210	Missense	distal	-7	no	18.166	18.201	EPSD	GDSC;CCLE	8.808	Up-regulation
CMGC_CDK_CDK5_CDK5_ST	O15169	AXIN1	Q00535	CDK5	S217	C221Y	221	Missense	distal	4	no	18.166	18.172	EPSD	GDSC;CCLE	8.808	Up-regulation
CMGC_CDK_CDK5_CDK5_ST	O15169	AXIN1	Q00535	CDK5	S283	A277T	277	Missense	distal	-6	no	8.857	8.943	EPSD	GDSC;CCLE	8.808	Up-regulation
CMGC_CDK_CDK5_CDK5_ST	P49768	PSEN1	Q00535	CDK5	S324	N331S	331	Missense	distal	7	no	9.836	9.840	EPSD	GDSC	8.808	Up-regulation
CMGC_CDK_CDK5_CDK5_ST	P02545	LMNA	Q00535	CDK5	T3	M1I	1	Missense	proximal	-2	no	16.497	16.748	EPSD	GDSC	8.808	Up-regulation
CMGC_CDK_CDK5_CDK5_ST	P02545	LMNA	Q00535	CDK5	S5	M1I	1	Missense	distal	-4	no	10.475	10.929	EPSD	GDSC	8.808	Up-regulation
CMGC_CDK_CDK5_CDK5_ST	P02545	LMNA	Q00535	CDK5	S398	S403P	403	Missense	distal	5	no	10.525	10.513	EPSD	GDSC;CCLE	8.808	Down-regulation
CMGC_CDK_CDK5_CDK5_ST	P02545	LMNA	Q00535	CDK5	T655	S662I	662	Missense	distal	7	no	9.686	9.679	EPSD	GDSC;CCLE	8.808	Down-regulation
CMGC_CDK_CDK5_CDK5_ST	P02545	LMNA	Q00535	CDK5	T655	N660I	660	Missense	distal	5	no	9.686	9.660	EPSD	GDSC;CCLE	8.808	Down-regulation
CMGC_CDK_CDK5_CDK5_ST	P02545	LMNA	Q00535	CDK5	S657	S662I	662	Missense	distal	5	no	18.641	18.551	EPSD	GDSC;CCLE	8.808	Down-regulation
CMGC_CDK_CDK5_CDK5_ST	P02545	LMNA	Q00535	CDK5	S657	N660I	660	Missense	distal	3	no	18.641	18.415	EPSD	GDSC;CCLE	8.808	Down-regulation
CMGC_CDK_CDK5_CDK5_ST	Q9Y490	TLN1	Q00535	CDK5	T354	N352S	352	Missense	proximal	-2	no	9.636	9.750	EPSD	GDSC;CCLE	8.808	Up-regulation
CMGC_CDK_CDK5_CDK5_ST	Q9Y490	TLN1	Q00535	CDK5	S425	S423*	423	Missense	proximal	-2	no	19.342	18.360	PhosphoSitePlus	GDSC	8.808	Down-regulation
CMGC_CDK_CDK5_CDK5_ST	Q9Y490	TLN1	Q00535	CDK5	S940	K943N	943	Missense	distal	3	no	9.125	7.192	EPSD	GDSC;CCLE	8.808	Loss
CMGC_CDK_CDK5_CDK5_ST	Q9Y490	TLN1	Q00535	CDK5	T941	K943N	943	Missense	proximal	2	no	16.845	16.651	EPSD	GDSC;CCLE	8.808	Down-regulation
CMGC_CDK_CDK5_CDK5_ST	Q9Y490	TLN1	Q00535	CDK5	S1260	P1264S	1264	Missense	distal	4	no	9.702	9.704	EPSD	GDSC	8.808	Up-regulation
CMGC_CDK_CDK5_CDK5_ST	Q9Y490	TLN1	Q00535	CDK5	T1263	P1264S	1264	Missense	proximal	1	no	16.873	4.972	EPSD	GDSC	8.808	Loss
CMGC_CDK_CDK5_CDK5_ST	Q9Y490	TLN1	Q00535	CDK5	S1694	R1690H	1690	Missense	distal	-4	no	9.218	8.998	EPSD	GDSC;CCLE	8.808	Down-regulation
CMGC_CDK_CDK5_CDK5_ST	Q15833	STXBP2	Q00535	CDK5	S78	E81D	81	Missense	distal	3	no	16.781	16.715	EPSD	GDSC;CCLE	8.808	Down-regulation
CMGC_CDK_CDK5_CDK5_ST	Q15833	STXBP2	Q00535	CDK5	S458	R459W	459	Missense	proximal	1	no	8.894	-0.965	EPSD	GDSC	8.808	Loss
CMGC_CDK_CDK5_CDK5_ST	Q15833	STXBP2	Q00535	CDK5	S458	R465P	465	Missense	distal	7	no	8.894	8.892	EPSD	GDSC;CCLE	8.808	Down-regulation
CMGC_CDK_CDK5_CDK5_ST	Q15833	STXBP2	Q00535	CDK5	S458	L460M	460	Missense	proximal	2	no	8.894	8.868	EPSD	GDSC;CCLE	8.808	Down-regulation
CMGC_CDK_CDK5_CDK5_ST	Q15833	STXBP2	Q00535	CDK5	S473	Q471*	471	Missense	proximal	-2	no	9.688	8.799	EPSD	GDSC	8.808	Loss
CMGC_CDK_CDK5_CDK5_ST	P08670	VIM	Q00535	CDK5	S459	T458A	458	Missense	proximal	-1	no	9.622	9.617	EPSD	GDSC;CCLE	8.808	Down-regulation
CAMK_CAMK1_PNCK_ST	P08238	HSP90AB1	Q6P2M8	PNCK	S58	P62H	62	Missense	distal	4	no	2.362	2.206	EPSD	GDSC;CCLE	1.882	Down-regulation
CAMK_CAMK1_PNCK_ST	P08238	HSP90AB1	Q6P2M8	PNCK	T89	T85S	85	Missense	distal	-4	no	7.022	6.795	PhosphoSitePlus	GDSC;CCLE	1.882	Down-regulation
CAMK_CAMK1_PNCK_ST	P08238	HSP90AB1	Q6P2M8	PNCK	S255	E257Q	257	Missense	proximal	2	no	2.222	1.681	EPSD	GDSC;CCLE	1.882	Loss
CAMK_CAMK1_PNCK_ST	P08238	HSP90AB1	Q6P2M8	PNCK	S261	E257Q	257	Missense	distal	-4	no	2.394	2.089	EPSD	GDSC;CCLE	1.882	Down-regulation
CAMK_CAMK1_PNCK_ST	P08238	HSP90AB1	Q6P2M8	PNCK	T616	M617R	617	Missense	proximal	1	no	5.610	5.597	EPSD	GDSC;CCLE	1.882	Down-regulation
CAMK_CAMK1_PNCK_ST	P08238	HSP90AB1	Q6P2M8	PNCK	T616	A610T	610	Missense	distal	-6	no	5.610	5.779	EPSD	GDSC;CCLE	1.882	Up-regulation
CAMK_CAMK1_PNCK_ST	O43432	EIF4G3	Q6P2M8	PNCK	S164	P169A	169	Missense	distal	5	no	1.723	1.988	EPSD	GDSC;CCLE	1.882	Gain
CAMK_CAMK1_PNCK_ST	O43432	EIF4G3	Q6P2M8	PNCK	S273	R276Q	276	Missense	distal	3	no	3.051	2.791	EPSD	GDSC	1.882	Down-regulation
CAMK_CAMK1_PNCK_ST	O43432	EIF4G3	Q6P2M8	PNCK	S305	P312S	312	Missense	distal	7	no	1.887	1.915	EPSD	GDSC	1.882	Up-regulation
CAMK_CAMK1_PNCK_ST	O43432	EIF4G3	Q6P2M8	PNCK	S352	I359V	359	Missense	distal	7	no	2.762	2.363	EPSD	GDSC;CCLE	1.882	Down-regulation
CAMK_CAMK1_PNCK_ST	O43432	EIF4G3	Q6P2M8	PNCK	T417	P421L	421	Missense	distal	4	no	1.780	1.928	EPSD	GDSC;CCLE	1.882	Gain
CAMK_CAMK1_PNCK_ST	O43432	EIF4G3	Q6P2M8	PNCK	S1156	F1151S	1151	Missense	distal	-5	no	7.091	6.929	PhosphoSitePlus	GDSC;CCLE	1.882	Down-regulation
CAMK_CAMK1_PNCK_ST	O43432	EIF4G3	Q6P2M8	PNCK	S1156	D1162V	1162	Missense	distal	6	no	7.091	7.210	PhosphoSitePlus	GDSC	1.882	Up-regulation
CAMK_CAMK1_PNCK_ST	O43432	EIF4G3	Q6P2M8	PNCK	S1157	F1151S	1151	Missense	distal	-6	no	2.078	2.115	EPSD	GDSC;CCLE	1.882	Up-regulation
CAMK_CAMK1_PNCK_ST	O43432	EIF4G3	Q6P2M8	PNCK	S1157	D1162V	1162	Missense	distal	5	no	2.078	2.523	EPSD	GDSC	1.882	Up-regulation
CAMK_PKD_PRKD2_ST	P50552	VASP	Q9BZL6	PRKD2	S157	R155Q	155	Missense	proximal	-2	no	3.561	3.383	EPSD;PhosphoSitePlus	GDSC	1.791	Down-regulation
CAMK_PKD_PRKD2_ST	P50552	VASP	Q9BZL6	PRKD2	S157	N158H	158	Missense	proximal	1	no	3.561	3.570	EPSD;PhosphoSitePlus	GDSC	1.791	Up-regulation
CAMK_PKD_PRKD2_ST	P50552	VASP	Q9BZL6	PRKD2	S339	Q345*	345	Missense	distal	6	no	1.797	1.716	EPSD	GDSC	1.791	Loss
CAMK_PKD_PRKD2_ST	Q8WYL5	SSH1	Q9BZL6	PRKD2	T989	S994R	994	Missense	distal	5	no	1.881	1.830	EPSD	GDSC	1.791	Down-regulation
CAMK_PKD_PRKD2_ST	Q9UQL6	HDAC5	Q9BZL6	PRKD2	S1108	E1114Q	1114	Missense	distal	6	no	2.046	2.044	EPSD	GDSC	1.791	Down-regulation
CAMK_PKD_PRKD2_ST	Q13563	PKD2	Q9BZL6	PRKD2	S801	S804N	804	Missense	distal	3	no	3.671	3.692	PhosphoSitePlus	GDSC	1.791	Up-regulation
CAMK_PKD_PRKD2_ST	Q01105	SET	Q9BZL6	PRKD2	S63	D56N	56	Missense	distal	-7	no	1.965	1.961	EPSD	GDSC	1.791	Down-regulation
CAMK_PKD_PRKD2_ST	Q01105	SET	Q9BZL6	PRKD2	S201	E200A	200	Missense	proximal	-1	no	2.143	2.230	EPSD	GDSC;CCLE	1.791	Up-regulation
CAMK_PKD_PRKD2_ST	Q9BZL6	PRKD2	Q9BZL6	PRKD2	S244	S245T	245	Missense	proximal	1	no	2.068	1.887	EPSD	GDSC;CCLE	1.791	Down-regulation
CAMK_PKD_PRKD2_ST	Q9BZL6	PRKD2	Q9BZL6	PRKD2	S396	R400Q	400	Missense	distal	4	no	1.906	1.727	EPSD	GDSC;CCLE	1.791	Loss
CAMK_PKD_PRKD2_ST	Q9BZL6	PRKD2	Q9BZL6	PRKD2	S710	R708C	708	Missense	proximal	-2	no	3.496	3.318	EPSD	GDSC;CCLE	1.791	Down-regulation
CAMK_PKD_PRKD2_ST	P16144	ITGB4	Q9BZL6	PRKD2	T829	D836N	836	Missense	distal	7	no	2.144	2.128	EPSD	GDSC;CCLE	1.791	Down-regulation
CAMK_PKD_PRKD2_ST	P16144	ITGB4	Q9BZL6	PRKD2	T829	P835A	835	Missense	distal	6	no	2.144	2.203	EPSD	GDSC	1.791	Up-regulation
CAMK_PKD_PRKD2_ST	P16144	ITGB4	Q9BZL6	PRKD2	T982	Q987R	987	Missense	distal	5	no	1.935	1.882	EPSD	GDSC;CCLE	1.791	Down-regulation
CAMK_PKD_PRKD2_ST	P16144	ITGB4	Q9BZL6	PRKD2	S1069	G1073C	1073	Missense	distal	4	no	1.956	1.774	EPSD	GDSC;CCLE	1.791	Loss
CAMK_PKD_PRKD2_ST	P16144	ITGB4	Q9BZL6	PRKD2	S1084	R1077C	1077	Missense	distal	-7	no	2.192	2.173	EPSD	GDSC;CCLE	1.791	Down-regulation
CAMK_PKD_PRKD2_ST	P16144	ITGB4	Q9BZL6	PRKD2	S1511	T1514P	1514	Missense	distal	3	no	3.025	3.019	EPSD	GDSC	1.791	Down-regulation
CAMK_PKD_PRKD2_ST	P16144	ITGB4	Q9BZL6	PRKD2	S1604	V1600M	1600	Missense	distal	-4	no	2.353	2.348	EPSD	GDSC;CCLE	1.791	Down-regulation
CAMK_PKD_PRKD2_ST	P16144	ITGB4	Q9BZL6	PRKD2	S1604	W1608*	1608	Missense	distal	4	no	2.353	2.496	EPSD	GDSC	1.791	Up-regulation
CAMK_PKD_PRKD2_ST	P16144	ITGB4	Q9BZL6	PRKD2	S1736	E1729K	1729	Missense	distal	-7	no	1.879	1.893	PhosphoSitePlus	GDSC;CCLE	1.791	Up-regulation
CAMK_PKD_PRKD2_ST	P16144	ITGB4	Q9BZL6	PRKD2	S1761	P1755L	1755	Missense	distal	-6	no	1.902	1.914	EPSD	GDSC	1.791	Up-regulation
CAMK_PKD_PRKD2_ST	P16144	ITGB4	Q9BZL6	PRKD2	S1791	T1793P	1793	Missense	proximal	2	no	1.912	1.905	EPSD	GDSC	1.791	Down-regulation
CAMK_PKD_PRKD2_ST	P16144	ITGB4	Q9BZL6	PRKD2	S1791	R1794Q	1794	Missense	distal	3	no	1.912	1.873	EPSD	GDSC	1.791	Down-regulation
CAMK_PKD_PRKD2_ST	P16144	ITGB4	Q9BZL6	PRKD2	T1797	T1793P	1793	Missense	distal	-4	no	2.609	2.616	EPSD	GDSC	1.791	Up-regulation
CAMK_PKD_PRKD2_ST	P16144	ITGB4	Q9BZL6	PRKD2	T1797	R1794Q	1794	Missense	distal	-3	no	2.609	1.535	EPSD	GDSC	1.791	Loss
CAMK_PKD_PRKD2_ST	Q13671	RIN1	Q9BZL6	PRKD2	S210	P211L	211	Missense	proximal	1	no	1.710	1.972	EPSD	GDSC	1.791	Gain
CAMK_PKD_PRKD2_ST	Q13671	RIN1	Q9BZL6	PRKD2	S255	T253P	253	Missense	proximal	-2	no	2.005	1.943	EPSD	GDSC	1.791	Down-regulation
CAMK_PKD_PRKD2_ST	Q13671	RIN1	Q9BZL6	PRKD2	S424	E420*	420	Missense	distal	-4	no	1.945	1.953	EPSD	GDSC	1.791	Up-regulation
CAMK_PKD_PRKD2_ST	Q13671	RIN1	Q9BZL6	PRKD2	S611	R607Q	607	Missense	distal	-4	no	2.887	2.870	EPSD	GDSC;CCLE	1.791	Down-regulation
CAMK_PKD_PRKD2_ST	Q99828	CIB1	Q9BZL6	PRKD2	S78	C74Y	74	Missense	distal	-4	no	3.471	3.474	PhosphoSitePlus	GDSC;CCLE	1.791	Up-regulation
CAMK_PKD_PRKD2_ST	Q99828	CIB1	Q9BZL6	PRKD2	S78	R72*	72	Missense	distal	-6	no	3.471	3.481	PhosphoSitePlus	GDSC	1.791	Up-regulation
CAMK_CAMK2_CAMK2B_ST	Q16625	OCLN	Q13554	CAMK2B	T305	V308L	308	Missense	distal	3	no	136.260	135.598	EPSD	GDSC	127.946	Down-regulation
CAMK_CAMK2_CAMK2B_ST	P16949	STMN1	Q13554	CAMK2B	S16	E10K	10	Missense	distal	-6	no	143.674	144.285	PhosphoSitePlus	GDSC;CCLE	127.946	Up-regulation
CAMK_CAMK2_CAMK2B_ST	P16949	STMN1	Q13554	CAMK2B	S16	E10*	10	Missense	distal	-6	no	143.674	142.236	PhosphoSitePlus	GDSC	127.946	Down-regulation
STE_STE20_PAKB_PAK5_ST	Q9P286	PAK5	Q9P286	PAK5	S223	S223L	223	Missense	central	0	yes	3.901	0.000	EPSD	GDSC	3.202	Loss
STE_STE20_PAKB_PAK5_ST	Q9P286	PAK5	Q9P286	PAK5	S271	N274S	274	Missense	distal	3	no	3.457	3.540	EPSD	GDSC	3.202	Up-regulation
STE_STE20_PAKB_PAK5_ST	Q9P286	PAK5	Q9P286	PAK5	S658	D665N	665	Missense	distal	7	no	4.211	4.304	EPSD	GDSC	3.202	Up-regulation
STE_STE20_PAKB_PAK5_ST	P15923	TCF3	Q9P286	PAK5	S110	A109S	109	Missense	proximal	-1	no	4.236	4.622	EPSD	GDSC;CCLE	3.202	Up-regulation
CAMK_CASK_CASK_ST	O14936	CASK	O14936	CASK	S562	R557K	557	Missense	distal	-5	no	3.665	3.527	EPSD	GDSC	2.569	Down-regulation
CAMK_CASK_CASK_ST	O14936	CASK	O14936	CASK	S562	M559I	559	Missense	distal	-3	no	3.665	3.602	EPSD	GDSC	2.569	Down-regulation
TK_FGFR_FGFR3_Y	P35222	CTNNB1	P22607	FGFR3	Y670	Y670*	670	Missense	central	0	yes	0.000	0.000	EPSD	GDSC	0.000	Loss
TK_FGFR_FGFR3_Y	P60484	PTEN	P22607	FGFR3	Y177	Y177*	177	Missense	central	0	yes	0.000	0.000	EPSD	GDSC	0.000	Loss
Other_TLK_TLK2_ST	Q9NVP2	ASF1B	Q86UE8	TLK2	S198	E196V	196	Missense	proximal	-2	no	4.580	2.697	PhosphoSitePlus	GDSC;CCLE	1.183	Down-regulation
STE_STE7_MEK3_MAP2K6_ST	P53778	MAPK12	P52564	MAP2K6	T183	A178T	178	Missense	distal	-5	no	9.659	9.812	EPSD;PhosphoSitePlus	GDSC;CCLE	1.858	Up-regulation
STE_STE7_MEK3_MAP2K6_ST	P52564	MAP2K6	P52564	MAP2K6	S35	T28A	28	Missense	distal	-7	no	2.336	2.393	EPSD	GDSC	1.858	Up-regulation
STE_STE7_MEK3_MAP2K6_ST	P52564	MAP2K6	P52564	MAP2K6	S201	S201G	201	Missense	central	0	yes	2.269	0.000	EPSD	GDSC	1.858	Loss
STE_STE7_MEK3_MAP2K6_ST	P52564	MAP2K6	P52564	MAP2K6	S207	S201G	201	Missense	distal	-6	no	8.152	8.154	PhosphoSitePlus;EPSD	GDSC	1.858	Up-regulation
STE_STE7_MEK3_MAP2K6_ST	Q9ULV5	HSF4	P52564	MAP2K6	T471	I472V	472	Missense	proximal	1	no	8.305	8.324	PhosphoSitePlus	GDSC	1.858	Up-regulation
STE_STE7_MEK3_MAP2K6_ST	Q9NQU5	PAK6	P52564	MAP2K6	T371	P370L	370	Missense	proximal	-1	no	2.056	2.239	EPSD	GDSC	1.858	Up-regulation
CK1_VRK_VRK2_ST	P38432	COIL	Q86Y07	VRK2	S184	K181R	181	Missense	distal	-3	no	100.519	107.056	PhosphoSitePlus	GDSC;CCLE	34.967	Up-regulation
CK1_VRK_VRK2_ST	Q9UHP3	USP25	Q86Y07	VRK2	T680	L675F	675	Missense	distal	-5	no	97.663	97.746	PhosphoSitePlus;EPSD	GDSC;CCLE	34.967	Up-regulation
CK1_VRK_VRK2_ST	Q9UHP3	USP25	Q86Y07	VRK2	S745	S747N	747	Missense	proximal	2	no	103.353	97.998	EPSD;PhosphoSitePlus	GDSC;CCLE	34.967	Down-regulation
CK1_VRK_VRK2_ST	Q96EV8	DTNBP1	Q86Y07	VRK2	S53	R54S	54	Missense	proximal	1	no	44.147	42.854	EPSD	GDSC	34.967	Down-regulation
CK1_VRK_VRK2_ST	Q96EV8	DTNBP1	Q86Y07	VRK2	S53	L49*	49	Missense	distal	-4	no	44.147	43.932	EPSD	GDSC	34.967	Down-regulation
CK1_VRK_VRK2_ST	Q96EV8	DTNBP1	Q86Y07	VRK2	T115	A116T	116	Missense	proximal	1	no	45.631	46.660	EPSD	GDSC;CCLE	34.967	Up-regulation
CK1_VRK_VRK2_ST	Q96EV8	DTNBP1	Q86Y07	VRK2	T119	A116T	116	Missense	distal	-3	no	54.713	54.403	EPSD	GDSC;CCLE	34.967	Down-regulation
AGC_DMPK_ROCK_ROCK1_ST	Q14160	SCRIB	Q13464	ROCK1	S1378	V1380L	1380	Missense	proximal	2	no	39.728	38.223	EPSD;PhosphoSitePlus	GDSC	31.796	Down-regulation
AGC_DMPK_ROCK_ROCK1_ST	P35241	RDX	Q13464	ROCK1	T564	K563N	563	Missense	proximal	-1	no	33.014	30.644	PhosphoSitePlus	GDSC;CCLE	31.796	Loss
AGC_DMPK_ROCK_ROCK1_ST	P61587	RND3	Q13464	ROCK1	S218	H219R	219	Missense	proximal	1	no	51.293	50.733	EPSD;PhosphoSitePlus	GDSC;CCLE	31.796	Down-regulation
AGC_DMPK_ROCK_ROCK1_ST	P61587	RND3	Q13464	ROCK1	S222	H219R	219	Missense	distal	-3	no	22.817	37.427	EPSD	GDSC;CCLE	31.796	Gain
AGC_DMPK_ROCK_ROCK1_ST	P19634	SLC9A1	Q13464	ROCK1	S648	R647L	647	Missense	proximal	-1	no	35.012	31.519	EPSD	GDSC;CCLE	31.796	Loss
AGC_DMPK_ROCK_ROCK1_ST	P19634	SLC9A1	Q13464	ROCK1	T653	R647L	647	Missense	distal	-6	no	43.592	37.697	PhosphoSitePlus	GDSC;CCLE	31.796	Down-regulation
AGC_DMPK_ROCK_ROCK1_ST	Q9NRY4	ARHGAP35	Q13464	ROCK1	S589	Q586K	586	Missense	distal	-3	no	31.610	32.782	EPSD	GDSC;CCLE	31.796	Gain
AGC_DMPK_ROCK_ROCK1_ST	Q9NRY4	ARHGAP35	Q13464	ROCK1	S843	H841R	841	Missense	proximal	-2	no	22.316	33.451	EPSD	GDSC;CCLE	31.796	Gain
AGC_DMPK_ROCK_ROCK1_ST	Q9NRY4	ARHGAP35	Q13464	ROCK1	S1290	E1291A	1291	Missense	proximal	1	no	34.442	34.341	EPSD	GDSC;CCLE	31.796	Down-regulation
AGC_DMPK_ROCK_ROCK1_ST	Q9Y613	FHOD1	Q13464	ROCK1	S357	R351W	351	Missense	distal	-6	no	38.076	34.749	EPSD	GDSC;CCLE	31.796	Down-regulation
AGC_DMPK_ROCK_ROCK1_ST	Q9Y613	FHOD1	Q13464	ROCK1	S357	S357P	357	Missense	central	0	yes	38.076	0.000	EPSD	GDSC;CCLE	31.796	Loss
AGC_DMPK_ROCK_ROCK1_ST	Q9Y613	FHOD1	Q13464	ROCK1	S357	K355E	355	Missense	proximal	-2	no	38.076	32.833	EPSD	GDSC;CCLE	31.796	Down-regulation
AGC_DMPK_ROCK_ROCK1_ST	Q9Y613	FHOD1	Q13464	ROCK1	T1010	Y1004*	1004	Missense	distal	-6	no	32.912	24.930	EPSD	GDSC	31.796	Loss
AGC_DMPK_ROCK_ROCK1_ST	Q9Y613	FHOD1	Q13464	ROCK1	S1052	A1047T	1047	Missense	distal	-5	no	37.714	37.152	EPSD	GDSC;CCLE	31.796	Down-regulation
AGC_DMPK_ROCK_ROCK1_ST	Q8N264	ARHGAP24	Q13464	ROCK1	S108	Q110R	110	Missense	proximal	2	no	34.488	35.643	EPSD	GDSC;CCLE	31.796	Up-regulation
AGC_DMPK_ROCK_ROCK1_ST	Q8N264	ARHGAP24	Q13464	ROCK1	S437	S439G	439	Missense	proximal	2	no	33.437	33.657	EPSD;PhosphoSitePlus	GDSC	31.796	Up-regulation
AGC_DMPK_ROCK_ROCK1_ST	P15311	EZR	Q13464	ROCK1	T576	I580V	580	Missense	distal	4	no	32.964	32.312	EPSD	GDSC;CCLE	31.796	Down-regulation
AGC_DMPK_ROCK_ROCK1_ST	P14136	GFAP	Q13464	ROCK1	S13	R12H	12	Missense	proximal	-1	no	41.059	38.491	EPSD;PhosphoSitePlus	GDSC;CCLE	31.796	Down-regulation
AGC_DMPK_ROCK_ROCK1_ST	P14136	GFAP	Q13464	ROCK1	S16	R12H	12	Missense	distal	-4	no	33.905	30.924	EPSD	GDSC;CCLE	31.796	Loss
AGC_DMPK_ROCK_ROCK1_ST	P60484	PTEN	Q13464	ROCK1	S179	Y177*	177	Missense	proximal	-2	no	43.618	9.472	EPSD	GDSC	31.796	Loss
AGC_DMPK_ROCK_ROCK1_ST	P60484	PTEN	Q13464	ROCK1	S227	R233*	233	Missense	distal	6	no	33.700	35.518	EPSD	GDSC	31.796	Up-regulation
AGC_DMPK_ROCK_ROCK1_ST	P60484	PTEN	Q13464	ROCK1	S229	R233*	233	Missense	distal	4	no	35.730	33.807	PhosphoSitePlus;EPSD	GDSC	31.796	Down-regulation
AGC_DMPK_ROCK_ROCK1_ST	P60484	PTEN	Q13464	ROCK1	T232	R233*	233	Missense	proximal	1	no	37.654	38.686	EPSD;PhosphoSitePlus	GDSC	31.796	Up-regulation
AGC_DMPK_ROCK_ROCK1_ST	P60484	PTEN	Q13464	ROCK1	S338	R335*	335	Missense	distal	-3	no	42.148	12.961	EPSD	GDSC	31.796	Loss
AGC_DMPK_ROCK_ROCK1_ST	P17661	DES	Q13464	ROCK1	T76	Y83H	83	Missense	distal	7	no	37.343	36.886	EPSD;PhosphoSitePlus	GDSC	31.796	Down-regulation
AGC_DMPK_ROCK_ROCK1_ST	P17661	DES	Q13464	ROCK1	T76	S82T	82	Missense	distal	6	no	37.343	37.782	EPSD;PhosphoSitePlus	GDSC	31.796	Up-regulation
AGC_DMPK_ROCK_ROCK1_ST	P17661	DES	Q13464	ROCK1	T77	Y83H	83	Missense	distal	6	no	32.526	32.091	EPSD;PhosphoSitePlus	GDSC	31.796	Down-regulation
AGC_DMPK_ROCK_ROCK1_ST	P17661	DES	Q13464	ROCK1	T77	S82T	82	Missense	distal	5	no	32.526	32.230	EPSD;PhosphoSitePlus	GDSC	31.796	Down-regulation
AGC_DMPK_ROCK_ROCK1_ST	P17661	DES	Q13464	ROCK1	S81	Y83H	83	Missense	proximal	2	no	34.041	33.844	EPSD	GDSC	31.796	Down-regulation
AGC_DMPK_ROCK_ROCK1_ST	P17661	DES	Q13464	ROCK1	S81	S82T	82	Missense	proximal	1	no	34.041	33.456	EPSD	GDSC	31.796	Down-regulation
AGC_DMPK_ROCK_ROCK1_ST	Q14CB8	ARHGAP19	Q13464	ROCK1	S422	R421H	421	Missense	proximal	-1	no	36.767	34.198	PhosphoSitePlus	GDSC	31.796	Down-regulation
AGC_DMPK_ROCK_ROCK1_ST	Q14CB8	ARHGAP19	Q13464	ROCK1	S424	R421H	421	Missense	distal	-3	no	34.748	20.137	EPSD	GDSC	31.796	Loss
AGC_DMPK_ROCK_ROCK1_ST	O14950	MYL12B	Q13464	ROCK1	T10	R14H	14	Missense	distal	4	no	34.832	34.244	EPSD	GDSC;CCLE	31.796	Down-regulation
AGC_DMPK_ROCK_ROCK1_ST	O14950	MYL12B	Q13464	ROCK1	T10	Q16*	16	Missense	distal	6	no	34.832	35.533	EPSD	GDSC	31.796	Up-regulation
AGC_DMPK_ROCK_ROCK1_ST	O14950	MYL12B	Q13464	ROCK1	T11	R14H	14	Missense	distal	3	no	36.960	36.864	EPSD	GDSC;CCLE	31.796	Down-regulation
AGC_DMPK_ROCK_ROCK1_ST	O14950	MYL12B	Q13464	ROCK1	T11	Q16*	16	Missense	distal	5	no	36.960	37.432	EPSD	GDSC	31.796	Up-regulation
AGC_DMPK_ROCK_ROCK1_ST	O14950	MYL12B	Q13464	ROCK1	T19	R14H	14	Missense	distal	-5	no	51.827	50.600	EPSD;PhosphoSitePlus	GDSC;CCLE	31.796	Down-regulation
AGC_DMPK_ROCK_ROCK1_ST	O14950	MYL12B	Q13464	ROCK1	T19	Q16*	16	Missense	distal	-3	no	51.827	27.523	EPSD;PhosphoSitePlus	GDSC	31.796	Loss
AGC_DMPK_ROCK_ROCK1_ST	O14950	MYL12B	Q13464	ROCK1	S20	R14H	14	Missense	distal	-6	no	40.125	36.606	PhosphoSitePlus;EPSD	GDSC;CCLE	31.796	Down-regulation
AGC_DMPK_ROCK_ROCK1_ST	O14950	MYL12B	Q13464	ROCK1	S20	Q16*	16	Missense	distal	-4	no	40.125	35.641	PhosphoSitePlus;EPSD	GDSC	31.796	Down-regulation
AGC_DMPK_ROCK_ROCK1_ST	Q16555	DPYSL2	Q13464	ROCK1	S427	S421F	421	Missense	distal	-6	no	33.068	28.849	EPSD	GDSC;CCLE	31.796	Loss
AGC_DMPK_ROCK_ROCK1_ST	Q16555	DPYSL2	Q13464	ROCK1	T555	A560V	560	Missense	distal	5	no	36.149	36.693	PhosphoSitePlus	GDSC	31.796	Up-regulation
AGC_DMPK_ROCK_ROCK1_ST	P07737	PFN1	Q13464	ROCK1	S30	V31A	31	Missense	proximal	1	no	33.777	33.420	EPSD	GDSC;CCLE	31.796	Down-regulation
AGC_DMPK_ROCK_ROCK1_ST	P07737	PFN1	Q13464	ROCK1	S58	D55H	55	Missense	distal	-3	no	44.060	38.228	EPSD	GDSC;CCLE	31.796	Down-regulation
AGC_DMPK_ROCK_ROCK1_ST	P35611	ADD1	Q13464	ROCK1	T480	H478Y	478	Missense	proximal	-2	no	36.112	42.670	EPSD;PhosphoSitePlus	GDSC	31.796	Up-regulation
AGC_DMPK_ROCK_ROCK1_ST	P35611	ADD1	Q13464	ROCK1	S481	H478Y	478	Missense	distal	-3	no	26.646	35.842	EPSD	GDSC	31.796	Gain
AGC_DMPK_ROCK_ROCK1_ST	P35611	ADD1	Q13464	ROCK1	S483	H478Y	478	Missense	distal	-5	no	36.513	36.413	EPSD	GDSC	31.796	Down-regulation
AGC_DMPK_ROCK_ROCK1_ST	P26038	MSN	Q13464	ROCK1	T66	V70L	70	Missense	distal	4	no	36.764	36.458	EPSD	GDSC	31.796	Down-regulation
AGC_DMPK_ROCK_ROCK1_ST	P26038	MSN	Q13464	ROCK1	S74	V70L	70	Missense	distal	-4	no	33.231	33.100	EPSD	GDSC	31.796	Down-regulation
AGC_DMPK_ROCK_ROCK1_ST	P26038	MSN	Q13464	ROCK1	S214	L218M	218	Missense	distal	4	no	30.658	32.017	EPSD	GDSC;CCLE	31.796	Gain
AGC_DMPK_ROCK_ROCK1_ST	O60237	PPP1R12B	Q13464	ROCK1	S51	R53K	53	Missense	proximal	2	no	41.048	41.375	EPSD	GDSC;CCLE	31.796	Up-regulation
AGC_DMPK_ROCK_ROCK1_ST	O60237	PPP1R12B	Q13464	ROCK1	S447	E453*	453	Missense	distal	6	no	37.915	38.639	EPSD	GDSC	31.796	Up-regulation
AGC_DMPK_ROCK_ROCK1_ST	O60237	PPP1R12B	Q13464	ROCK1	S618	R613W	613	Missense	distal	-5	no	37.825	35.543	EPSD	GDSC;CCLE	31.796	Down-regulation
AGC_DMPK_ROCK_ROCK1_ST	O60237	PPP1R12B	Q13464	ROCK1	S855	G851V	851	Missense	distal	-4	no	33.364	32.527	EPSD	GDSC;CCLE	31.796	Down-regulation
AGC_DMPK_ROCK_ROCK1_ST	O60237	PPP1R12B	Q13464	ROCK1	S855	Y850C	850	Missense	distal	-5	no	33.364	29.058	EPSD	GDSC;CCLE	31.796	Loss
AGC_DMPK_ROCK_ROCK1_ST	O60237	PPP1R12B	Q13464	ROCK1	T869	T871N	871	Missense	proximal	2	no	40.474	39.219	EPSD	GDSC;CCLE	31.796	Down-regulation
AGC_DMPK_ROCK_ROCK1_ST	O60237	PPP1R12B	Q13464	ROCK1	T869	T871I	871	Missense	proximal	2	no	40.474	37.895	EPSD	GDSC;CCLE	31.796	Down-regulation
AGC_DMPK_ROCK_ROCK1_ST	O60237	PPP1R12B	Q13464	ROCK1	S947	R940*	940	Missense	distal	-7	no	34.156	33.843	EPSD	GDSC	31.796	Down-regulation
AGC_DMPK_ROCK_ROCK1_ST	O43293	DAPK3	Q13464	ROCK1	T300	I307T	307	Missense	distal	7	no	33.498	33.809	EPSD	GDSC;CCLE	31.796	Up-regulation
AGC_DMPK_ROCK_ROCK1_ST	O43293	DAPK3	Q13464	ROCK1	S414	R411H	411	Missense	distal	-3	no	32.611	18.001	EPSD	GDSC;CCLE	31.796	Loss
AGC_DMPK_ROCK_ROCK1_ST	P08670	VIM	Q13464	ROCK1	S278	A281T	281	Missense	distal	3	no	40.007	40.154	EPSD	GDSC;CCLE	31.796	Up-regulation
AGC_DMPK_ROCK_ROCK1_ST	P08670	VIM	Q13464	ROCK1	S278	R273C	273	Missense	distal	-5	no	40.007	34.373	EPSD	GDSC;CCLE	31.796	Down-regulation
AGC_DMPK_ROCK_ROCK1_ST	P08670	VIM	Q13464	ROCK1	S325	A332V	332	Missense	distal	7	no	33.460	33.972	EPSD	GDSC;CCLE	31.796	Up-regulation
AGC_DMPK_ROCK_ROCK1_ST	Q05397	PTK2	Q13464	ROCK1	T460	C459G	459	Missense	proximal	-1	no	32.181	35.903	EPSD	GDSC;CCLE	31.796	Up-regulation
AGC_DMPK_ROCK_ROCK1_ST	Q05397	PTK2	Q13464	ROCK1	S463	C459G	459	Missense	distal	-4	no	32.060	34.442	EPSD	GDSC;CCLE	31.796	Up-regulation
AGC_DMPK_ROCK_ROCK1_ST	Q05397	PTK2	Q13464	ROCK1	S517	S517C	517	Missense	central	0	yes	36.405	0.000	EPSD	GDSC;CCLE	31.796	Loss
AGC_DMPK_ROCK_ROCK1_ST	Q05397	PTK2	Q13464	ROCK1	S580	P585R	585	Missense	distal	5	no	38.069	37.055	EPSD	GDSC;CCLE	31.796	Down-regulation
AGC_DMPK_ROCK_ROCK1_ST	Q05397	PTK2	Q13464	ROCK1	S732	P731S	731	Missense	proximal	-1	no	33.230	35.249	PhosphoSitePlus	GDSC;CCLE	31.796	Up-regulation
AGC_DMPK_ROCK_ROCK1_ST	Q05397	PTK2	Q13464	ROCK1	S732	P733T	733	Missense	proximal	1	no	33.230	32.842	PhosphoSitePlus	GDSC;CCLE	31.796	Down-regulation
AGC_DMPK_ROCK_ROCK1_ST	P53667	LIMK1	Q13464	ROCK1	S439	W434*	434	Missense	distal	-5	no	39.623	34.645	EPSD	GDSC	31.796	Down-regulation
AGC_DMPK_ROCK_ROCK1_ST	P53667	LIMK1	Q13464	ROCK1	S439	S439G	439	Missense	central	0	yes	39.623	0.000	EPSD	GDSC;CCLE	31.796	Loss
AGC_DMPK_ROCK_ROCK1_ST	P53667	LIMK1	Q13464	ROCK1	T508	R506C	506	Missense	proximal	-2	no	55.423	22.565	PhosphoSitePlus	GDSC;CCLE	31.796	Loss
AGC_DMPK_ROCK_ROCK1_ST	P48436	SOX9	Q13464	ROCK1	S64	E65*	65	Missense	proximal	1	no	32.369	32.490	EPSD	GDSC	31.796	Up-regulation
AGC_DMPK_ROCK_ROCK1_ST	P48436	SOX9	Q13464	ROCK1	S64	E63V	63	Missense	proximal	-1	no	32.369	33.572	EPSD	GDSC;CCLE	31.796	Up-regulation
AGC_DMPK_ROCK_ROCK1_ST	P48436	SOX9	Q13464	ROCK1	S181	K183R	183	Missense	proximal	2	no	49.170	48.843	PhosphoSitePlus	GDSC;CCLE	31.796	Down-regulation
AGC_DMPK_ROCK_ROCK1_ST	O14974	PPP1R12A	Q13464	ROCK1	S541	K538*	538	Missense	distal	-3	no	33.717	8.240	EPSD	GDSC	31.796	Loss
AGC_DMPK_ROCK_ROCK1_ST	O14974	PPP1R12A	Q13464	ROCK1	S541	E545K	545	Missense	distal	4	no	33.717	35.647	EPSD	GDSC;CCLE	31.796	Up-regulation
AGC_DMPK_ROCK_ROCK1_ST	O14974	PPP1R12A	Q13464	ROCK1	S903	R900*	900	Missense	distal	-3	no	33.551	4.364	EPSD	GDSC	31.796	Loss
AGC_DMPK_ROCK_ROCK1_ST	O14974	PPP1R12A	Q13464	ROCK1	S995	R993K	993	Missense	proximal	-2	no	37.434	29.683	EPSD	GDSC;CCLE	31.796	Loss
AGC_DMPK_ROCK_ROCK1_ST	Q9UPT6	MAPK8IP3	Q13464	ROCK1	S364	G369D	369	Missense	distal	5	no	37.309	37.895	EPSD;PhosphoSitePlus	GDSC;CCLE	31.796	Up-regulation
AGC_DMPK_ROCK_ROCK1_ST	Q9UPT6	MAPK8IP3	Q13464	ROCK1	S365	N372K	372	Missense	distal	7	no	34.517	33.537	EPSD;PhosphoSitePlus	GDSC;CCLE	31.796	Down-regulation
AGC_DMPK_ROCK_ROCK1_ST	Q9UPT6	MAPK8IP3	Q13464	ROCK1	S365	G369D	369	Missense	distal	4	no	34.517	33.368	EPSD;PhosphoSitePlus	GDSC;CCLE	31.796	Down-regulation
AGC_DMPK_ROCK_ROCK1_ST	Q9UPT6	MAPK8IP3	Q13464	ROCK1	S1191	S1191F	1191	Missense	central	0	yes	33.950	0.000	EPSD	GDSC;CCLE	31.796	Loss
AGC_DMPK_ROCK_ROCK1_ST	Q9UPT6	MAPK8IP3	Q13464	ROCK1	S1191	R1186*	1186	Missense	distal	-5	no	33.950	26.689	EPSD	GDSC	31.796	Loss
AGC_PKG_PRKG2_ST	P29474	NOS3	Q13237	PRKG2	S114	S114F	114	Missense	central	0	yes	57.772	0.000	EPSD	GDSC;CCLE	42.682	Loss
AGC_PKG_PRKG2_ST	P29474	NOS3	Q13237	PRKG2	S114	G116S	116	Missense	proximal	2	no	57.772	57.519	EPSD	GDSC	42.682	Down-regulation
AGC_PKG_PRKG2_ST	P29474	NOS3	Q13237	PRKG2	S633	R627Q	627	Missense	distal	-6	no	74.934	74.395	EPSD;PhosphoSitePlus	GDSC;CCLE	42.682	Down-regulation
AGC_PKG_PRKG2_ST	P29474	NOS3	Q13237	PRKG2	S633	R628Q	628	Missense	distal	-5	no	74.934	74.961	EPSD;PhosphoSitePlus	GDSC	42.682	Up-regulation
AGC_PKG_PRKG2_ST	P29474	NOS3	Q13237	PRKG2	S1177	R1174C	1174	Missense	distal	-3	no	74.260	35.736	EPSD;PhosphoSitePlus	GDSC;CCLE	42.682	Loss
AGC_PKG_PRKG2_ST	P29474	NOS3	Q13237	PRKG2	S1177	R1172C	1172	Missense	distal	-5	no	74.260	74.278	EPSD;PhosphoSitePlus	GDSC;CCLE	42.682	Up-regulation
AGC_PKG_PRKG2_ST	P29474	NOS3	Q13237	PRKG2	S1177	T1175S	1175	Missense	proximal	-2	no	74.260	66.663	EPSD;PhosphoSitePlus	GDSC;CCLE	42.682	Down-regulation
AGC_PKG_PRKG2_ST	P29474	NOS3	Q13237	PRKG2	S1177	T1170K	1170	Missense	distal	-7	no	74.260	73.470	EPSD;PhosphoSitePlus	GDSC	42.682	Down-regulation
AGC_PKG_PRKG2_ST	P29474	NOS3	Q13237	PRKG2	S1177	I1173T	1173	Missense	distal	-4	no	74.260	71.828	EPSD;PhosphoSitePlus	GDSC;CCLE	42.682	Down-regulation
AGC_PKG_PRKG2_ST	P04626	ERBB2	Q13237	PRKG2	S1049	R1048C	1048	Missense	proximal	-1	no	61.155	61.328	EPSD	GDSC;CCLE	42.682	Up-regulation
AGC_PKG_PRKG2_ST	P04626	ERBB2	Q13237	PRKG2	S1050	R1048C	1048	Missense	proximal	-2	no	61.015	26.924	EPSD	GDSC;CCLE	42.682	Loss
AGC_PKG_PRKG2_ST	P04626	ERBB2	Q13237	PRKG2	S1051	R1048C	1048	Missense	distal	-3	no	44.772	6.248	EPSD	GDSC;CCLE	42.682	Loss
AGC_PKG_PRKG2_ST	P04626	ERBB2	Q13237	PRKG2	S1054	R1048C	1048	Missense	distal	-6	no	49.219	49.321	EPSD	GDSC;CCLE	42.682	Up-regulation
AGC_PKG_PRKG2_ST	P29350	PTPN6	Q13237	PRKG2	S10	R7*	7	Missense	distal	-3	no	48.068	44.305	EPSD	GDSC	42.682	Down-regulation
AGC_PKG_PRKG2_ST	P29350	PTPN6	Q13237	PRKG2	S32	D38E	38	Missense	distal	6	no	62.940	62.528	EPSD	GDSC;CCLE	42.682	Down-regulation
AGC_PKG_PRKG2_ST	P29350	PTPN6	Q13237	PRKG2	S32	F39V	39	Missense	distal	7	no	62.940	63.591	EPSD	GDSC;CCLE	42.682	Up-regulation
AGC_PKG_PRKG2_ST	P29350	PTPN6	Q13237	PRKG2	S534	S534L	534	Missense	central	0	yes	52.871	0.000	EPSD	GDSC	42.682	Loss
AGC_PKG_PRKG2_ST	P29350	PTPN6	Q13237	PRKG2	T540	S534L	534	Missense	distal	-6	no	44.587	39.322	EPSD	GDSC	42.682	Loss
AGC_PKG_PRKG2_ST	P09619	PDGFRB	Q13237	PRKG2	S748	M754T	754	Missense	distal	6	no	46.193	45.746	EPSD	GDSC;CCLE	42.682	Down-regulation
AGC_PKG_PRKG2_ST	Q14847	LASP1	Q13237	PRKG2	S61	A66V	66	Missense	distal	5	no	45.490	45.257	EPSD	GDSC	42.682	Down-regulation
AGC_PKG_PRKG2_ST	P32929	CTH	Q13237	PRKG2	S377	R375*	375	Missense	proximal	-2	no	68.731	57.937	PhosphoSitePlus	GDSC	42.682	Down-regulation
TK_Fer_FER_Y	Q16555	DPYSL2	P16591	FER	Y499	R496H	496	Missense	distal	-3	no	0.191	0.182	PhosphoSitePlus;EPSD	GDSC;CCLE	0.101	Down-regulation
TK_Fer_FER_Y	P15311	EZR	P16591	FER	Y478	P476S	476	Missense	proximal	-2	no	0.203	0.204	PhosphoSitePlus;EPSD	GDSC;CCLE	0.101	Up-regulation
TK_Fer_FER_Y	P40763	STAT3	P16591	FER	Y705	C712Y	712	Missense	distal	7	no	0.182	0.193	PhosphoSitePlus	GDSC;CCLE	0.101	Up-regulation
TK_Fer_FER_Y	P16591	FER	P16591	FER	Y615	V621F	621	Missense	distal	6	no	0.186	0.176	EPSD;PhosphoSitePlus	GDSC;CCLE	0.101	Down-regulation
TK_Fer_FER_Y	P16591	FER	P16591	FER	Y714	V713M	713	Missense	proximal	-1	no	0.205	0.202	PhosphoSitePlus;EPSD	GDSC;CCLE	0.101	Down-regulation
TK_Fer_FER_Y	P16591	FER	P16591	FER	Y714	R707L	707	Missense	distal	-7	no	0.205	0.193	PhosphoSitePlus;EPSD	GDSC;CCLE	0.101	Down-regulation
TK_Fer_FER_Y	P14923	JUP	P16591	FER	Y550	V554A	554	Missense	distal	4	no	0.211	0.226	PhosphoSitePlus	GDSC;CCLE	0.101	Up-regulation
CMGC_CDK_CDK9_CDK9_ST	O00267	SUPT5H	P50750	CDK9	S686	G682D	682	Missense	distal	-4	no	4.609	4.577	EPSD	GDSC;CCLE	1.932	Down-regulation
CMGC_CDK_CDK9_CDK9_ST	O00267	SUPT5H	P50750	CDK9	T806	G811D	811	Missense	distal	5	no	5.999	5.883	EPSD;PhosphoSitePlus	GDSC;CCLE	1.932	Down-regulation
CMGC_CDK_CDK9_CDK9_ST	O00267	SUPT5H	P50750	CDK9	T806	D810G	810	Missense	distal	4	no	5.999	6.046	EPSD;PhosphoSitePlus	GDSC;CCLE	1.932	Up-regulation
CMGC_CDK_CDK9_CDK9_ST	O00267	SUPT5H	P50750	CDK9	S812	G811D	811	Missense	proximal	-1	no	2.029	2.016	EPSD	GDSC;CCLE	1.932	Down-regulation
CMGC_CDK_CDK9_CDK9_ST	O00267	SUPT5H	P50750	CDK9	S812	D810G	810	Missense	proximal	-2	no	2.029	2.056	EPSD	GDSC;CCLE	1.932	Up-regulation
CMGC_CDK_CDK9_CDK9_ST	O00267	SUPT5H	P50750	CDK9	T814	G811D	811	Missense	distal	-3	no	6.210	6.211	PhosphoSitePlus;EPSD	GDSC;CCLE	1.932	Up-regulation
CMGC_CDK_CDK9_CDK9_ST	O00267	SUPT5H	P50750	CDK9	T814	D810G	810	Missense	distal	-4	no	6.210	6.242	PhosphoSitePlus;EPSD	GDSC;CCLE	1.932	Up-regulation
CMGC_CDK_CDK9_CDK9_ST	O00267	SUPT5H	P50750	CDK9	T828	T828M	828	Missense	central	0	yes	4.793	0.000	EPSD	GDSC;CCLE	1.932	Loss
CMGC_CDK_CDK9_CDK9_ST	O00267	SUPT5H	P50750	CDK9	S867	Q869L	869	Missense	proximal	2	no	5.181	5.287	EPSD	GDSC;CCLE	1.932	Up-regulation
CMGC_CDK_CDK9_CDK9_ST	P84022	SMAD3	P50750	CDK9	T179	P172T	172	Missense	distal	-7	no	5.191	5.230	EPSD;PhosphoSitePlus	GDSC;CCLE	1.932	Up-regulation
CMGC_CDK_CDK9_CDK9_ST	P24928	POLR2A	P50750	CDK9	T46	T46M	46	Missense	central	0	yes	1.956	0.000	EPSD	GDSC;CCLE	1.932	Loss
CMGC_CDK_CDK9_CDK9_ST	P24928	POLR2A	P50750	CDK9	T368	I367T	367	Missense	proximal	-1	no	6.146	6.167	EPSD	GDSC;CCLE	1.932	Up-regulation
CMGC_CDK_CDK9_CDK9_ST	P24928	POLR2A	P50750	CDK9	T1568	P1569L	1569	Missense	proximal	1	no	5.440	-0.159	EPSD	GDSC;CCLE	1.932	Loss
CMGC_CDK_CDK9_CDK9_ST	P24928	POLR2A	P50750	CDK9	S1571	P1569L	1569	Missense	proximal	-2	no	5.570	4.781	EPSD	GDSC;CCLE	1.932	Down-regulation
CMGC_CDK_CDK9_CDK9_ST	P24928	POLR2A	P50750	CDK9	S1571	T1568S	1568	Missense	distal	-3	no	5.570	5.515	EPSD	GDSC;CCLE	1.932	Down-regulation
CMGC_CDK_CDK9_CDK9_ST	P24928	POLR2A	P50750	CDK9	S1574	P1569L	1569	Missense	distal	-5	no	6.846	6.467	EPSD	GDSC;CCLE	1.932	Down-regulation
CMGC_CDK_CDK9_CDK9_ST	P24928	POLR2A	P50750	CDK9	S1574	T1568S	1568	Missense	distal	-6	no	6.846	7.081	EPSD	GDSC;CCLE	1.932	Up-regulation
CMGC_CDK_CDK9_CDK9_ST	P24928	POLR2A	P50750	CDK9	S1616	S1616F	1616	Missense	central	0	yes	4.310	0.000	EPSD;PhosphoSitePlus	GDSC;CCLE	1.932	Loss
CMGC_CDK_CDK9_CDK9_ST	P24928	POLR2A	P50750	CDK9	T1618	S1616F	1616	Missense	proximal	-2	no	2.563	2.044	EPSD;PhosphoSitePlus	GDSC;CCLE	1.932	Down-regulation
CMGC_CDK_CDK9_CDK9_ST	P24928	POLR2A	P50750	CDK9	S1619	S1616F	1616	Missense	distal	-3	no	4.556	4.648	EPSD;PhosphoSitePlus	GDSC;CCLE	1.932	Up-regulation
CMGC_CDK_CDK9_CDK9_ST	P24928	POLR2A	P50750	CDK9	S1766	P1764L	1764	Missense	proximal	-2	no	4.505	3.716	EPSD	GDSC;CCLE	1.932	Down-regulation
CMGC_CDK_CDK9_CDK9_ST	P24928	POLR2A	P50750	CDK9	S1847	Y1853H	1853	Missense	distal	6	no	4.003	4.046	EPSD	GDSC;CCLE	1.932	Up-regulation
CMGC_CDK_CDK9_CDK9_ST	P24928	POLR2A	P50750	CDK9	S1849	Y1853H	1853	Missense	distal	4	no	2.265	2.277	EPSD	GDSC;CCLE	1.932	Up-regulation
CMGC_CDK_CDK9_CDK9_ST	P24928	POLR2A	P50750	CDK9	S1850	Y1853H	1853	Missense	distal	3	no	4.655	4.680	EPSD	GDSC;CCLE	1.932	Up-regulation
CMGC_CDK_CDK9_CDK9_ST	P24928	POLR2A	P50750	CDK9	T1854	Y1853H	1853	Missense	proximal	-1	no	4.083	4.098	EPSD	GDSC;CCLE	1.932	Up-regulation
CMGC_CDK_CDK9_CDK9_ST	P24928	POLR2A	P50750	CDK9	T1856	P1862T	1862	Missense	distal	6	no	2.320	1.987	EPSD	GDSC;CCLE	1.932	Down-regulation
CMGC_CDK_CDK9_CDK9_ST	P24928	POLR2A	P50750	CDK9	T1856	Y1853H	1853	Missense	distal	-3	no	2.320	2.308	EPSD	GDSC;CCLE	1.932	Down-regulation
CMGC_CDK_CDK9_CDK9_ST	P24928	POLR2A	P50750	CDK9	S1857	P1862T	1862	Missense	distal	5	no	4.315	4.156	EPSD	GDSC;CCLE	1.932	Down-regulation
CMGC_CDK_CDK9_CDK9_ST	P24928	POLR2A	P50750	CDK9	S1857	Y1853H	1853	Missense	distal	-4	no	4.315	4.325	EPSD	GDSC;CCLE	1.932	Up-regulation
CMGC_CDK_CDK9_CDK9_ST	P24928	POLR2A	P50750	CDK9	S1861	P1862T	1862	Missense	proximal	1	no	3.999	-0.020	EPSD	GDSC;CCLE	1.932	Loss
CMGC_CDK_CDK9_CDK9_ST	P24928	POLR2A	P50750	CDK9	T1863	P1862T	1862	Missense	proximal	-1	no	2.535	2.523	EPSD	GDSC;CCLE	1.932	Down-regulation
CMGC_CDK_CDK9_CDK9_ST	P24928	POLR2A	P50750	CDK9	S1864	P1862T	1862	Missense	proximal	-2	no	4.218	3.726	EPSD	GDSC;CCLE	1.932	Down-regulation
CMGC_CDK_CDK9_CDK9_ST	P24928	POLR2A	P50750	CDK9	S1868	P1862T	1862	Missense	distal	-6	no	3.736	3.370	EPSD	GDSC;CCLE	1.932	Down-regulation
CMGC_CDK_CDK9_CDK9_ST	P24928	POLR2A	P50750	CDK9	T1957	I1961V	1961	Missense	distal	4	no	3.835	3.826	EPSD	GDSC;CCLE	1.932	Down-regulation
CMGC_CDK_CDK9_CDK9_ST	P24928	POLR2A	P50750	CDK9	S1958	I1961V	1961	Missense	distal	3	no	6.241	6.255	EPSD	GDSC;CCLE	1.932	Up-regulation
CMGC_CDK_CDK9_CDK9_ST	P24928	POLR2A	P50750	CDK9	S1962	I1961V	1961	Missense	proximal	-1	no	4.945	4.943	EPSD	GDSC;CCLE	1.932	Down-regulation
CMGC_CDK_CDK9_CDK9_ST	Q6PGQ7	BORA	P50750	CDK9	S27	S27G	27	Missense	central	0	yes	3.858	0.000	EPSD	GDSC;CCLE	1.932	Loss
CMGC_CDK_CDK9_CDK9_ST	Q6PGQ7	BORA	P50750	CDK9	S32	T38I	38	Missense	distal	6	no	2.557	2.326	EPSD	GDSC;CCLE	1.932	Down-regulation
CMGC_CDK_CDK9_CDK9_ST	Q6PGQ7	BORA	P50750	CDK9	S32	S27G	27	Missense	distal	-5	no	2.557	2.194	EPSD	GDSC;CCLE	1.932	Down-regulation
CMGC_CDK_CDK9_CDK9_ST	Q6PGQ7	BORA	P50750	CDK9	S41	T38I	38	Missense	distal	-3	no	4.055	4.082	EPSD	GDSC;CCLE	1.932	Up-regulation
CMGC_CDK_CDK9_CDK9_ST	Q6PGQ7	BORA	P50750	CDK9	S41	A40T	40	Missense	proximal	-1	no	4.055	4.078	EPSD	GDSC;CCLE	1.932	Up-regulation
CMGC_CDK_CDK9_CDK9_ST	Q6PGQ7	BORA	P50750	CDK9	S41	F45V	45	Missense	distal	4	no	4.055	4.067	EPSD	GDSC;CCLE	1.932	Up-regulation
CMGC_CDK_CDK9_CDK9_ST	Q6PGQ7	BORA	P50750	CDK9	T52	F45V	45	Missense	distal	-7	no	4.733	4.723	EPSD	GDSC;CCLE	1.932	Down-regulation
CMGC_CDK_CDK9_CDK9_ST	Q6PGQ7	BORA	P50750	CDK9	S112	T115A	115	Missense	distal	3	no	3.786	3.699	EPSD	GDSC;CCLE	1.932	Down-regulation
CMGC_CDK_CDK9_CDK9_ST	Q6PGQ7	BORA	P50750	CDK9	S183	L187I	187	Missense	distal	4	no	4.367	4.370	EPSD	GDSC	1.932	Up-regulation
CMGC_CDK_CDK9_CDK9_ST	Q6PGQ7	BORA	P50750	CDK9	S183	E178K	178	Missense	distal	-5	no	4.367	4.425	EPSD	GDSC	1.932	Up-regulation
CMGC_CDK_CDK9_CDK9_ST	Q6PGQ7	BORA	P50750	CDK9	S190	S191P	191	Missense	proximal	1	no	1.403	5.137	EPSD	GDSC;CCLE	1.932	Gain
CMGC_CDK_CDK9_CDK9_ST	Q6PGQ7	BORA	P50750	CDK9	S252	A258V	258	Missense	distal	6	no	5.464	5.458	EPSD	GDSC;CCLE	1.932	Down-regulation
CMGC_CDK_CDK9_CDK9_ST	Q6PGQ7	BORA	P50750	CDK9	S268	G264*	264	Missense	distal	-4	no	5.318	5.230	EPSD	GDSC	1.932	Down-regulation
CMGC_CDK_CDK9_CDK9_ST	Q6PGQ7	BORA	P50750	CDK9	S270	G264*	264	Missense	distal	-6	no	6.009	5.830	EPSD	GDSC	1.932	Down-regulation
CMGC_CDK_CDK9_CDK9_ST	Q9H0D6	XRN2	P50750	CDK9	T439	R446I	446	Missense	distal	7	no	5.819	5.879	PhosphoSitePlus	GDSC;CCLE	1.932	Up-regulation
CMGC_CDK_CDK9_CDK9_ST	Q9H0D6	XRN2	P50750	CDK9	S448	P449A	449	Missense	proximal	1	no	2.947	-2.217	EPSD	GDSC;CCLE	1.932	Loss
CMGC_CDK_CDK9_CDK9_ST	Q9H0D6	XRN2	P50750	CDK9	S448	S451C	451	Missense	distal	3	no	2.947	2.643	EPSD	GDSC;CCLE	1.932	Down-regulation
CMGC_CDK_CDK9_CDK9_ST	Q9H0D6	XRN2	P50750	CDK9	S448	R446I	446	Missense	proximal	-2	no	2.947	2.782	EPSD	GDSC;CCLE	1.932	Down-regulation
CMGC_CDK_CDK9_CDK9_ST	Q9H0D6	XRN2	P50750	CDK9	S471	Q467*	467	Missense	distal	-4	no	4.531	4.382	EPSD	GDSC	1.932	Down-regulation
CMGC_CDK_CDK9_CDK9_ST	Q9H0D6	XRN2	P50750	CDK9	S790	R793Q	793	Missense	distal	3	no	2.214	2.338	EPSD	GDSC;CCLE	1.932	Up-regulation
CMGC_CDK_CDK9_CDK9_ST	Q9H0D6	XRN2	P50750	CDK9	S861	N862S	862	Missense	proximal	1	no	2.157	1.476	EPSD	GDSC	1.932	Loss
CMGC_CDK_CDK9_CDK9_ST	P37231	PPARG	P50750	CDK9	S112	S112C	112	Missense	central	0	yes	5.604	0.000	PhosphoSitePlus	GDSC;CCLE	1.932	Loss
CMGC_CDK_CDK9_CDK9_ST	P10275	AR	P50750	CDK9	S516	E523D	523	Missense	distal	7	no	5.379	5.450	EPSD	GDSC	1.932	Up-regulation
CMGC_CDK_CDK9_CDK9_ST	Q15596	NCOA2	P50750	CDK9	S400	N401S	401	Missense	proximal	1	no	2.325	1.644	EPSD	GDSC;CCLE	1.932	Loss
CMGC_CDK_CDK9_CDK9_ST	Q15596	NCOA2	P50750	CDK9	S402	N401S	401	Missense	proximal	-1	no	4.947	4.993	EPSD	GDSC;CCLE	1.932	Up-regulation
CMGC_CDK_CDK9_CDK9_ST	Q15596	NCOA2	P50750	CDK9	S421	I427M	427	Missense	distal	6	no	2.627	2.713	EPSD	GDSC;CCLE	1.932	Up-regulation
CMGC_CDK_CDK9_CDK9_ST	Q15596	NCOA2	P50750	CDK9	S421	S420G	420	Missense	proximal	-1	no	2.627	2.565	EPSD	GDSC;CCLE	1.932	Down-regulation
CMGC_CDK_CDK9_CDK9_ST	Q15596	NCOA2	P50750	CDK9	T457	A464V	464	Missense	distal	7	no	5.049	5.034	EPSD	GDSC;CCLE	1.932	Down-regulation
CMGC_CDK_CDK9_CDK9_ST	Q15596	NCOA2	P50750	CDK9	S469	A464V	464	Missense	distal	-5	no	5.622	5.615	EPSD;PhosphoSitePlus	GDSC;CCLE	1.932	Down-regulation
CMGC_CDK_CDK9_CDK9_ST	Q15596	NCOA2	P50750	CDK9	S487	S487L	487	Missense	central	0	yes	5.333	0.000	EPSD;PhosphoSitePlus	GDSC;CCLE	1.932	Loss
CMGC_CDK_CDK9_CDK9_ST	Q15596	NCOA2	P50750	CDK9	S487	M485L	485	Missense	proximal	-2	no	5.333	5.179	EPSD;PhosphoSitePlus	GDSC;CCLE	1.932	Down-regulation
CMGC_CDK_CDK9_CDK9_ST	Q15596	NCOA2	P50750	CDK9	S493	S487L	487	Missense	distal	-6	no	5.367	4.910	PhosphoSitePlus;EPSD	GDSC;CCLE	1.932	Down-regulation
CMGC_CDK_CDK9_CDK9_ST	Q15596	NCOA2	P50750	CDK9	S720	D714E	714	Missense	distal	-6	no	1.924	2.023	EPSD	GDSC;CCLE	1.932	Gain
CMGC_CDK_CDK9_CDK9_ST	Q15596	NCOA2	P50750	CDK9	S721	D714E	714	Missense	distal	-7	no	2.132	2.118	EPSD	GDSC;CCLE	1.932	Down-regulation
CMGC_CDK_CDK9_CDK9_ST	Q15596	NCOA2	P50750	CDK9	S721	E718V	718	Missense	distal	-3	no	2.132	2.149	EPSD	GDSC;CCLE	1.932	Up-regulation
CMGC_CDK_CDK9_CDK9_ST	Q15596	NCOA2	P50750	CDK9	S736	K738R	738	Missense	proximal	2	no	5.598	5.621	EPSD	GDSC;CCLE	1.932	Up-regulation
CMGC_CDK_CDK9_CDK9_ST	Q15596	NCOA2	P50750	CDK9	S895	P888S	888	Missense	distal	-7	no	5.047	5.052	EPSD	GDSC;CCLE	1.932	Up-regulation
CMGC_CDK_CDK9_CDK9_ST	Q15596	NCOA2	P50750	CDK9	S895	Q894*	894	Missense	proximal	-1	no	5.047	4.975	EPSD	GDSC	1.932	Down-regulation
CMGC_CDK_CDK9_CDK9_ST	Q15596	NCOA2	P50750	CDK9	S1211	I1210M	1210	Missense	proximal	-1	no	2.248	2.259	EPSD	GDSC;CCLE	1.932	Up-regulation
CMGC_CDK_CDK9_CDK9_ST	Q15596	NCOA2	P50750	CDK9	S1211	S1211R	1211	Missense	central	0	yes	2.248	0.000	EPSD	GDSC;CCLE	1.932	Loss
CMGC_CDK_CDK9_CDK9_ST	P06400	RB1	P50750	CDK9	S567	W563*	563	Missense	distal	-4	no	4.316	4.272	EPSD	GDSC	1.932	Down-regulation
CMGC_CDK_CDK9_CDK9_ST	P06400	RB1	P50750	CDK9	S567	S567*	567	Missense	central	0	yes	4.316	0.000	EPSD	GDSC	1.932	Loss
CMGC_CDK_CDK9_CDK9_ST	P06400	RB1	P50750	CDK9	S608	T601S	601	Missense	distal	-7	no	4.435	4.400	EPSD	GDSC;CCLE	1.932	Down-regulation
CMGC_CDK_CDK9_CDK9_ST	P06400	RB1	P50750	CDK9	S780	R787*	787	Missense	distal	7	no	5.296	5.526	EPSD	GDSC	1.932	Up-regulation
CMGC_CDK_CDK9_CDK9_ST	P06400	RB1	P50750	CDK9	S788	R787*	787	Missense	proximal	-1	no	5.074	5.020	EPSD	GDSC	1.932	Down-regulation
CMGC_CDK_CDK9_CDK9_ST	P06400	RB1	P50750	CDK9	S794	G801*	801	Missense	distal	7	no	2.098	2.287	EPSD	GDSC	1.932	Up-regulation
CMGC_CDK_CDK9_CDK9_ST	P06400	RB1	P50750	CDK9	S794	R787*	787	Missense	distal	-7	no	2.098	2.138	EPSD	GDSC	1.932	Up-regulation
CMGC_CDK_CDK9_CDK9_ST	P06400	RB1	P50750	CDK9	S795	G801*	801	Missense	distal	6	no	5.687	5.347	PhosphoSitePlus;EPSD	GDSC	1.932	Down-regulation
CMGC_CDK_CDK9_CDK9_ST	P06400	RB1	P50750	CDK9	S807	G801*	801	Missense	distal	-6	no	4.492	4.312	EPSD;PhosphoSitePlus	GDSC	1.932	Down-regulation
CMGC_CDK_CDK9_CDK9_ST	P06400	RB1	P50750	CDK9	T821	L819V	819	Missense	proximal	-2	no	4.624	4.762	EPSD	GDSC;CCLE	1.932	Up-regulation
CMGC_CDK_CDK9_CDK9_ST	P06400	RB1	P50750	CDK9	T826	L819V	819	Missense	distal	-7	no	4.640	4.631	EPSD	GDSC;CCLE	1.932	Down-regulation
CMGC_CDK_CDK9_CDK9_ST	P04637	TP53	P50750	CDK9	S33	Q38*	38	Missense	distal	5	no	5.662	5.213	EPSD;PhosphoSitePlus	GDSC	1.932	Down-regulation
CMGC_CDK_CDK9_CDK9_ST	P04637	TP53	P50750	CDK9	T81	A74S	74	Missense	distal	-7	no	4.981	4.923	EPSD	GDSC;CCLE	1.932	Down-regulation
CMGC_CDK_CDK9_CDK9_ST	P04637	TP53	P50750	CDK9	S127	Y126*	126	Missense	proximal	-1	no	4.849	4.815	EPSD	GDSC	1.932	Down-regulation
CMGC_CDK_CDK9_CDK9_ST	P04637	TP53	P50750	CDK9	S127	K120*	120	Missense	distal	-7	no	4.849	4.893	EPSD	GDSC	1.932	Up-regulation
CMGC_CDK_CDK9_CDK9_ST	P04637	TP53	P50750	CDK9	T150	Q144*	144	Missense	distal	-6	no	5.274	4.845	EPSD	GDSC	1.932	Down-regulation
CMGC_CDK_CDK9_CDK9_ST	P04637	TP53	P50750	CDK9	T150	W146*	146	Missense	distal	-4	no	5.274	5.230	EPSD	GDSC	1.932	Down-regulation
CMGC_CDK_CDK9_CDK9_ST	P04637	TP53	P50750	CDK9	T312	R306*	306	Missense	distal	-6	no	2.262	2.000	EPSD	GDSC	1.932	Down-regulation
CMGC_CDK_CDK9_CDK9_ST	P04637	TP53	P50750	CDK9	T312	Q317*	317	Missense	distal	5	no	2.262	1.813	EPSD	GDSC	1.932	Loss
CMGC_CDK_CDK9_CDK9_ST	P04637	TP53	P50750	CDK9	T312	K319*	319	Missense	distal	7	no	2.262	2.509	EPSD	GDSC	1.932	Up-regulation
CMGC_CDK_CDK9_CDK9_ST	P04637	TP53	P50750	CDK9	S313	R306*	306	Missense	distal	-7	no	2.130	2.170	EPSD	GDSC	1.932	Up-regulation
CMGC_CDK_CDK9_CDK9_ST	P04637	TP53	P50750	CDK9	S313	Q317*	317	Missense	distal	4	no	2.130	1.999	EPSD	GDSC	1.932	Down-regulation
CMGC_CDK_CDK9_CDK9_ST	P04637	TP53	P50750	CDK9	S313	K319*	319	Missense	distal	6	no	2.130	1.681	EPSD	GDSC	1.932	Loss
CMGC_CDK_CDK9_CDK9_ST	P04637	TP53	P50750	CDK9	S315	Q317*	317	Missense	proximal	2	no	5.402	5.580	EPSD;PhosphoSitePlus	GDSC	1.932	Up-regulation
CMGC_CDK_CDK9_CDK9_ST	P04637	TP53	P50750	CDK9	S315	K319*	319	Missense	distal	4	no	5.402	5.314	EPSD;PhosphoSitePlus	GDSC	1.932	Down-regulation
CMGC_CDK_CDK9_CDK9_ST	P04637	TP53	P50750	CDK9	T387	G389W	389	Missense	proximal	2	no	1.910	1.935	EPSD	GDSC;CCLE	1.932	Gain
CAMK_CAMKL_MELK_MELK_ST	Q14680	MELK	Q14680	MELK	T56	P52A	52	Missense	distal	-4	no	244.425	242.747	EPSD;PhosphoSitePlus	GDSC;CCLE	155.919	Down-regulation
CAMK_CAMKL_MELK_MELK_ST	Q14680	MELK	Q14680	MELK	S253	M254V	254	Missense	proximal	1	no	226.646	225.495	EPSD;PhosphoSitePlus	GDSC	155.919	Down-regulation
CAMK_CAMKL_MELK_MELK_ST	Q14680	MELK	Q14680	MELK	S253	L257V	257	Missense	distal	4	no	226.646	224.992	EPSD;PhosphoSitePlus	GDSC;CCLE	155.919	Down-regulation
CAMK_CAMKL_MELK_MELK_ST	Q14680	MELK	Q14680	MELK	S336	Q341K	341	Missense	distal	5	no	246.493	247.201	EPSD;PhosphoSitePlus	GDSC	155.919	Up-regulation
CAMK_CAMKL_MELK_MELK_ST	Q14680	MELK	Q14680	MELK	S343	Q341K	341	Missense	proximal	-2	no	217.006	219.136	EPSD;PhosphoSitePlus	GDSC	155.919	Up-regulation
CAMK_CAMKL_MELK_MELK_ST	Q14680	MELK	Q14680	MELK	S356	K351R	351	Missense	distal	-5	no	215.772	218.770	EPSD;PhosphoSitePlus	GDSC	155.919	Up-regulation
CAMK_CAMKL_MELK_MELK_ST	Q14680	MELK	Q14680	MELK	S431	Y438*	438	Missense	distal	7	no	216.244	185.233	EPSD;PhosphoSitePlus	GDSC	155.919	Down-regulation
CAMK_CAMKL_MELK_MELK_ST	Q14680	MELK	Q14680	MELK	T539	T542A	542	Missense	distal	3	no	236.033	241.699	EPSD;PhosphoSitePlus	GDSC;CCLE	155.919	Up-regulation
CAMK_CAMKL_MELK_MELK_ST	Q14680	MELK	Q14680	MELK	T539	K545I	545	Missense	distal	6	no	236.033	229.528	EPSD;PhosphoSitePlus	GDSC	155.919	Down-regulation
CAMK_CAMKL_MELK_MELK_ST	P30305	CDC25B	Q14680	MELK	S91	R93Q	93	Missense	proximal	2	no	158.041	146.887	EPSD	GDSC;CCLE	155.919	Loss
CAMK_CAMKL_MELK_MELK_ST	P30305	CDC25B	Q14680	MELK	S91	S89T	89	Missense	proximal	-2	no	158.041	159.767	EPSD	GDSC;CCLE	155.919	Up-regulation
CAMK_CAMKL_MELK_MELK_ST	P30305	CDC25B	Q14680	MELK	S160	V154A	154	Missense	distal	-6	no	148.702	158.206	EPSD	GDSC	155.919	Gain
CAMK_CAMKL_MELK_MELK_ST	P23588	EIF4B	Q14680	MELK	S57	T54A	54	Missense	distal	-3	no	170.173	170.729	EPSD	GDSC;CCLE	155.919	Up-regulation
CAMK_CAMKL_MELK_MELK_ST	P23588	EIF4B	Q14680	MELK	S406	R401G	401	Missense	distal	-5	no	239.515	230.596	PhosphoSitePlus;EPSD	GDSC;CCLE	155.919	Down-regulation
CAMK_CAMKL_MELK_MELK_ST	P23588	EIF4B	Q14680	MELK	S422	R415Q	415	Missense	distal	-7	no	213.941	208.817	EPSD;PhosphoSitePlus	GDSC;CCLE	155.919	Down-regulation
STE_STE7_MEK1_MAP2K1_ST	Q13148	TARDBP	Q02750	MAP2K1	S407	G400D	400	Missense	distal	-7	no	73.129	74.642	EPSD	GDSC;CCLE	68.590	Up-regulation
STE_STE7_MEK1_MAP2K1_ST	P28482	MAPK1	Q02750	MAP2K1	T185	T185A	185	Missense	central	0	yes	151.746	0.000	PhosphoSitePlus;EPSD	GDSC;CCLE	68.590	Loss
STE_STE7_MEK1_MAP2K1_ST	P28482	MAPK1	Q02750	MAP2K1	T190	T185A	185	Missense	distal	-5	no	118.072	118.223	EPSD	GDSC;CCLE	68.590	Up-regulation
STE_STE7_MEK1_MAP2K1_ST	P27361	MAPK3	Q02750	MAP2K1	T202	E203D	203	Missense	proximal	1	no	153.714	159.081	EPSD;PhosphoSitePlus	GDSC;CCLE	68.590	Up-regulation
STE_STE7_MEK1_MAP2K1_ST	P27361	MAPK3	Q02750	MAP2K1	T202	H197D	197	Missense	distal	-5	no	153.714	154.426	EPSD;PhosphoSitePlus	GDSC;CCLE	68.590	Up-regulation
STE_STE7_MEK1_MAP2K1_ST	P27361	MAPK3	Q02750	MAP2K1	T207	E203D	203	Missense	distal	-4	no	117.682	117.998	EPSD;PhosphoSitePlus	GDSC;CCLE	68.590	Up-regulation
STE_STE7_MEK1_MAP2K1_ST	P49841	GSK3B	Q02750	MAP2K1	S25	S21L	21	Missense	distal	-4	no	84.801	75.123	EPSD	GDSC;CCLE	68.590	Down-regulation
STE_STE7_MEK1_MAP2K1_ST	P05787	KRT8	Q02750	MAP2K1	S9	T6S	6	Missense	distal	-3	no	76.274	76.511	EPSD	GDSC;CCLE	68.590	Up-regulation
STE_STE7_MEK1_MAP2K1_ST	P05787	KRT8	Q02750	MAP2K1	S74	L76R	76	Missense	proximal	2	no	140.764	139.399	PhosphoSitePlus	GDSC;CCLE	68.590	Down-regulation
STE_STE7_MEK1_MAP2K1_ST	P05787	KRT8	Q02750	MAP2K1	T242	S243F	243	Missense	proximal	1	no	88.826	88.364	EPSD	GDSC;CCLE	68.590	Down-regulation
STE_STE7_MEK1_MAP2K1_ST	Q00613	HSF1	Q02750	MAP2K1	S290	R296H	296	Missense	distal	6	no	70.764	69.920	EPSD	GDSC;CCLE	68.590	Down-regulation
STE_STE7_MEK1_MAP2K1_ST	Q00613	HSF1	Q02750	MAP2K1	S291	R296H	296	Missense	distal	5	no	77.443	76.874	EPSD	GDSC;CCLE	68.590	Down-regulation
STE_STE7_MEK1_MAP2K1_ST	Q00613	HSF1	Q02750	MAP2K1	S292	R296H	296	Missense	distal	4	no	86.996	84.291	EPSD	GDSC;CCLE	68.590	Down-regulation
STE_STE7_MEK1_MAP2K1_ST	Q00613	HSF1	Q02750	MAP2K1	S314	P308L	308	Missense	distal	-6	no	68.744	68.314	EPSD	GDSC	68.590	Loss
STE_STE7_MEK1_MAP2K1_ST	Q00613	HSF1	Q02750	MAP2K1	S314	E312A	312	Missense	proximal	-2	no	68.744	67.040	EPSD	GDSC	68.590	Loss
STE_STE7_MEK1_MAP2K1_ST	Q00613	HSF1	Q02750	MAP2K1	S338	V345I	345	Missense	distal	7	no	77.009	76.767	EPSD	GDSC	68.590	Down-regulation
STE_STE7_MEK1_MAP2K1_ST	Q00613	HSF1	Q02750	MAP2K1	S461	S458I	458	Missense	distal	-3	no	80.089	80.699	EPSD	GDSC;CCLE	68.590	Up-regulation
STE_STE7_MEK1_MAP2K1_ST	P04049	RAF1	Q02750	MAP2K1	S259	Q253P	253	Missense	distal	-6	no	86.342	86.517	EPSD	GDSC	68.590	Up-regulation
STE_STE7_MEK1_MAP2K1_ST	P04049	RAF1	Q02750	MAP2K1	S338	E343G	343	Missense	distal	5	no	137.395	137.133	PhosphoSitePlus	GDSC;CCLE	68.590	Down-regulation
CAMK_CAMKL_QIK_SIK2_ST	P27986	PIK3R1	Q9H0K1	SIK2	S43	G41E	41	Missense	proximal	-2	no	1.583	1.608	EPSD	GDSC;CCLE	1.318	Up-regulation
CAMK_CAMKL_QIK_SIK2_ST	P27986	PIK3R1	Q9H0K1	SIK2	S541	S536I	536	Missense	distal	-5	no	2.328	2.404	EPSD;PhosphoSitePlus	GDSC;CCLE	1.318	Up-regulation
CAMK_CAMKL_QIK_SIK2_ST	Q9BV73	CEP250	Q9H0K1	SIK2	S462	Q469*	469	Missense	distal	7	no	1.338	1.343	EPSD	GDSC	1.318	Up-regulation
CAMK_CAMKL_QIK_SIK2_ST	Q9BV73	CEP250	Q9H0K1	SIK2	S1295	S1295C	1295	Missense	central	0	yes	1.387	0.000	EPSD	GDSC;CCLE	1.318	Loss
CAMK_CAMKL_QIK_SIK2_ST	Q9BV73	CEP250	Q9H0K1	SIK2	S1386	N1392Y	1392	Missense	distal	6	no	1.304	1.420	EPSD	GDSC;CCLE	1.318	Gain
CAMK_CAMKL_QIK_SIK2_ST	Q9BV73	CEP250	Q9H0K1	SIK2	S1601	A1606S	1606	Missense	distal	5	no	1.541	1.514	EPSD	GDSC;CCLE	1.318	Down-regulation
CAMK_CAMKL_QIK_SIK2_ST	Q9BV73	CEP250	Q9H0K1	SIK2	S2186	A2181V	2181	Missense	distal	-5	no	1.387	1.436	EPSD	GDSC;CCLE	1.318	Up-regulation
CAMK_CAMKL_QIK_SIK2_ST	Q9BV73	CEP250	Q9H0K1	SIK2	S2188	A2181V	2181	Missense	distal	-7	no	1.455	1.435	EPSD	GDSC;CCLE	1.318	Down-regulation
CAMK_CAMKL_QIK_SIK2_ST	Q9BV73	CEP250	Q9H0K1	SIK2	S2435	H2431P	2431	Missense	distal	-4	no	1.343	1.326	EPSD	GDSC	1.318	Down-regulation
CAMK_CAMKL_QIK_SIK2_ST	Q9UQL6	HDAC5	Q9H0K1	SIK2	S1108	E1114Q	1114	Missense	distal	6	no	1.261	1.375	EPSD	GDSC	1.318	Gain
CMGC_CDK_CDK4_CDK6_ST	P06400	RB1	Q00534	CDK6	S567	W563*	563	Missense	distal	-4	no	83.870	83.761	EPSD	GDSC	54.510	Down-regulation
CMGC_CDK_CDK4_CDK6_ST	P06400	RB1	Q00534	CDK6	S567	S567*	567	Missense	central	0	yes	83.870	0.000	EPSD	GDSC	54.510	Loss
CMGC_CDK_CDK4_CDK6_ST	P06400	RB1	Q00534	CDK6	S608	T601S	601	Missense	distal	-7	no	84.906	84.903	EPSD	GDSC;CCLE	54.510	Down-regulation
CMGC_CDK_CDK4_CDK6_ST	P06400	RB1	Q00534	CDK6	S780	R787*	787	Missense	distal	7	no	87.105	87.108	PhosphoSitePlus;EPSD	GDSC	54.510	Up-regulation
CMGC_CDK_CDK4_CDK6_ST	P06400	RB1	Q00534	CDK6	S788	R787*	787	Missense	proximal	-1	no	88.702	88.704	EPSD;PhosphoSitePlus	GDSC	54.510	Up-regulation
CMGC_CDK_CDK4_CDK6_ST	P06400	RB1	Q00534	CDK6	S795	G801*	801	Missense	distal	6	no	86.408	86.411	EPSD;PhosphoSitePlus	GDSC	54.510	Up-regulation
CMGC_CDK_CDK4_CDK6_ST	P06400	RB1	Q00534	CDK6	S807	G801*	801	Missense	distal	-6	no	90.350	90.337	EPSD;PhosphoSitePlus	GDSC	54.510	Down-regulation
CMGC_CDK_CDK4_CDK6_ST	P06400	RB1	Q00534	CDK6	T821	L819V	819	Missense	proximal	-2	no	86.637	86.556	EPSD;PhosphoSitePlus	GDSC;CCLE	54.510	Down-regulation
CMGC_CDK_CDK4_CDK6_ST	P06400	RB1	Q00534	CDK6	T826	L819V	819	Missense	distal	-7	no	88.837	89.130	EPSD;PhosphoSitePlus	GDSC;CCLE	54.510	Up-regulation
CMGC_CDK_CDK4_CDK6_ST	P06400	RB1	Q00534	CDK6	T841	S834*	834	Missense	distal	-7	no	57.504	56.725	EPSD	GDSC	54.510	Down-regulation
CMGC_CDK_CDK4_CDK6_ST	P06400	RB1	Q00534	CDK6	T841	E837K	837	Missense	distal	-4	no	57.504	57.735	EPSD	GDSC;CCLE	54.510	Up-regulation
CMGC_CDK_CDK4_CDK6_ST	Q08999	RBL2	Q00534	CDK6	T417	T423M	423	Missense	distal	6	no	86.030	85.983	EPSD	GDSC;CCLE	54.510	Down-regulation
CMGC_CDK_CDK4_CDK6_ST	Q08999	RBL2	Q00534	CDK6	S1035	M1029I	1029	Missense	distal	-6	no	86.166	86.161	EPSD;PhosphoSitePlus	GDSC	54.510	Down-regulation
CMGC_CDK_CDK4_CDK6_ST	Q08999	RBL2	Q00534	CDK6	S1068	R1070*	1070	Missense	proximal	2	no	85.983	85.984	EPSD	GDSC	54.510	Up-regulation
CMGC_CDK_CDK4_CDK6_ST	Q08999	RBL2	Q00534	CDK6	S1080	Y1076*	1076	Missense	distal	-4	no	85.244	85.225	EPSD	GDSC	54.510	Down-regulation
CMGC_CDK_CDK4_CDK6_ST	Q08999	RBL2	Q00534	CDK6	S1112	P1119A	1119	Missense	distal	7	no	84.949	84.748	EPSD	GDSC;CCLE	54.510	Down-regulation
CMGC_CDK_CDK4_CDK6_ST	P38936	CDKN1A	Q00534	CDK6	T57	E56*	56	Missense	proximal	-1	no	84.771	84.755	EPSD	GDSC	54.510	Down-regulation
CMGC_CDK_CDK4_CDK6_ST	P38936	CDKN1A	Q00534	CDK6	T145	R143Q	143	Missense	proximal	-2	no	54.973	54.953	EPSD	GDSC;CCLE	54.510	Down-regulation
CMGC_CDK_CDK4_CDK6_ST	Q96KS0	EGLN2	Q00534	CDK6	S74	T72N	72	Missense	proximal	-2	no	84.198	84.292	EPSD	GDSC;CCLE	54.510	Up-regulation
CMGC_CDK_CDK4_CDK6_ST	Q96KS0	EGLN2	Q00534	CDK6	S130	E123K	123	Missense	distal	-7	no	85.564	85.694	PhosphoSitePlus	GDSC	54.510	Up-regulation
CMGC_CDK_CDK4_CDK6_ST	Q96KS0	EGLN2	Q00534	CDK6	S155	M150V	150	Missense	distal	-5	no	57.175	57.127	EPSD	GDSC;CCLE	54.510	Down-regulation
CMGC_CDK_CDK4_CDK6_ST	P14618	PKM	Q00534	CDK6	T405	A402V	402	Missense	distal	-3	no	56.058	56.033	EPSD	GDSC;CCLE	54.510	Down-regulation
CMGC_CDK_CDK4_CDK6_ST	P21333	FLNA	Q00534	CDK6	S468	G475V	475	Missense	distal	7	no	84.390	84.550	EPSD	GDSC;CCLE	54.510	Up-regulation
CMGC_CDK_CDK4_CDK6_ST	P21333	FLNA	Q00534	CDK6	T938	N931D	931	Missense	distal	-7	no	83.439	83.093	EPSD	GDSC;CCLE	54.510	Down-regulation
CMGC_CDK_CDK4_CDK6_ST	P21333	FLNA	Q00534	CDK6	S1533	K1538N	1538	Missense	distal	5	no	85.451	85.400	EPSD	GDSC;CCLE	54.510	Down-regulation
CMGC_CDK_CDK4_CDK6_ST	P21333	FLNA	Q00534	CDK6	S1630	R1633P	1633	Missense	distal	3	no	83.760	85.875	EPSD	GDSC;CCLE	54.510	Up-regulation
CMGC_CDK_CDK4_CDK6_ST	P21333	FLNA	Q00534	CDK6	S2224	Q2219R	2219	Missense	distal	-5	no	83.999	84.044	EPSD	GDSC;CCLE	54.510	Up-regulation
CMGC_CDK_CDK4_CDK6_ST	P21333	FLNA	Q00534	CDK6	S2319	N2312D	2312	Missense	distal	-7	no	85.345	84.998	EPSD	GDSC;CCLE	54.510	Down-regulation
CMGC_CDK_CDK4_CDK6_ST	P21333	FLNA	Q00534	CDK6	S2319	N2312K	2312	Missense	distal	-7	no	85.345	85.611	EPSD	GDSC;CCLE	54.510	Up-regulation
CMGC_CDK_CDK4_CDK6_ST	P21333	FLNA	Q00534	CDK6	S2327	R2334C	2334	Missense	distal	7	no	84.700	84.751	EPSD	GDSC	54.510	Up-regulation
CMGC_CDK_CDK4_CDK6_ST	P21333	FLNA	Q00534	CDK6	S2338	R2334C	2334	Missense	distal	-4	no	56.455	56.536	EPSD	GDSC	54.510	Up-regulation
CMGC_CDK_CDK4_CDK6_ST	P21333	FLNA	Q00534	CDK6	S2640	P2638Q	2638	Missense	proximal	-2	no	82.692	82.896	EPSD	GDSC;CCLE	54.510	Up-regulation
CMGC_CDK_CDK4_CDK6_ST	P46527	CDKN1B	Q00534	CDK6	S178	G177S	177	Missense	proximal	-1	no	83.718	83.796	EPSD	GDSC;CCLE	54.510	Up-regulation
CMGC_CDK_CDK4_CDK6_ST	Q92879	CELF1	Q00534	CDK6	T295	S297P	297	Missense	proximal	2	no	55.475	55.469	EPSD	GDSC;CCLE	54.510	Down-regulation
CMGC_CDK_CDK4_CDK6_ST	Q92879	CELF1	Q00534	CDK6	S296	S297P	297	Missense	proximal	1	no	58.889	88.528	EPSD	GDSC;CCLE	54.510	Up-regulation
CMGC_CDK_CDK4_CDK6_ST	Q92879	CELF1	Q00534	CDK6	S299	S297P	297	Missense	proximal	-2	no	57.914	57.859	EPSD	GDSC;CCLE	54.510	Down-regulation
CMGC_CDK_CDK4_CDK6_ST	Q92879	CELF1	Q00534	CDK6	S300	S297P	297	Missense	distal	-3	no	86.266	86.198	EPSD	GDSC;CCLE	54.510	Down-regulation
CMGC_CDK_CDK4_CDK6_ST	Q92879	CELF1	Q00534	CDK6	S302	S297P	297	Missense	distal	-5	no	59.225	59.182	PhosphoSitePlus	GDSC;CCLE	54.510	Down-regulation
CMGC_CDK_CDK4_CDK6_ST	Q92879	CELF1	Q00534	CDK6	S304	S297P	297	Missense	distal	-7	no	55.227	55.625	EPSD	GDSC;CCLE	54.510	Up-regulation
CMGC_CDK_CDK4_CDK6_ST	P06748	NPM1	Q00534	CDK6	S217	P220L	220	Missense	distal	3	no	56.530	54.355	EPSD	GDSC;CCLE	54.510	Loss
CMGC_CDK_CDK4_CDK6_ST	P06748	NPM1	Q00534	CDK6	S217	N210S	210	Missense	distal	-7	no	56.530	57.138	EPSD	GDSC;CCLE	54.510	Up-regulation
CMGC_CDK_CDK4_CDK6_ST	P06748	NPM1	Q00534	CDK6	T219	P220L	220	Missense	proximal	1	no	88.146	-8.861	EPSD	GDSC;CCLE	54.510	Loss
CMGC_CDK_CDK4_CDK6_ST	P06748	NPM1	Q00534	CDK6	T234	P235S	235	Missense	proximal	1	no	86.772	57.133	EPSD	GDSC;CCLE	54.510	Down-regulation
CMGC_CDK_CDK4_CDK6_ST	P06748	NPM1	Q00534	CDK6	T237	P235S	235	Missense	proximal	-2	no	85.136	85.191	EPSD	GDSC;CCLE	54.510	Up-regulation
CMGC_CDK_CDK4_CDK6_ST	P06748	NPM1	Q00534	CDK6	S242	E245Q	245	Missense	distal	3	no	56.489	56.060	EPSD	GDSC	54.510	Down-regulation
CMGC_CDK_CDK4_CDK6_ST	P06748	NPM1	Q00534	CDK6	S242	P235S	235	Missense	distal	-7	no	56.489	56.092	EPSD	GDSC;CCLE	54.510	Down-regulation
CMGC_CDK_CDK8_CDK8_ST	P46531	NOTCH1	P49336	CDK8	S2136	P2133S	2133	Missense	distal	-3	no	39.195	39.086	EPSD	GDSC	26.151	Down-regulation
CMGC_CDK_CDK8_CDK8_ST	P46531	NOTCH1	P49336	CDK8	S2162	V2158I	2158	Missense	distal	-4	no	27.147	25.695	EPSD	GDSC;CCLE	26.151	Loss
CMGC_CDK_CDK8_CDK8_ST	P46531	NOTCH1	P49336	CDK8	S2163	V2158I	2158	Missense	distal	-5	no	41.287	40.979	EPSD	GDSC;CCLE	26.151	Down-regulation
CMGC_CDK_CDK8_CDK8_ST	P46531	NOTCH1	P49336	CDK8	S2215	P2216L	2216	Missense	proximal	1	no	40.600	14.747	EPSD	GDSC;CCLE	26.151	Loss
CMGC_CDK_CDK8_CDK8_ST	P46531	NOTCH1	P49336	CDK8	S2221	P2216L	2216	Missense	distal	-5	no	37.631	37.237	EPSD	GDSC;CCLE	26.151	Down-regulation
CMGC_CDK_CDK8_CDK8_ST	P46531	NOTCH1	P49336	CDK8	S2516	S2523*	2523	Missense	distal	7	no	48.751	47.673	EPSD;PhosphoSitePlus	GDSC	26.151	Down-regulation
CMGC_CDK_CDK8_CDK8_ST	P46531	NOTCH1	P49336	CDK8	S2524	S2523*	2523	Missense	proximal	-1	no	35.106	34.978	EPSD	GDSC	26.151	Down-regulation
CMGC_CDK_CDK8_CDK8_ST	P84022	SMAD3	P49336	CDK8	T179	P172T	172	Missense	distal	-7	no	49.631	49.658	EPSD;PhosphoSitePlus	GDSC;CCLE	26.151	Up-regulation
CMGC_CDK_CDK8_CDK8_ST	Q01094	E2F1	P49336	CDK8	S307	G309E	309	Missense	proximal	2	no	31.092	29.774	EPSD	GDSC;CCLE	26.151	Down-regulation
CMGC_CDK_CDK8_CDK8_ST	Q01094	E2F1	P49336	CDK8	T311	G309E	309	Missense	proximal	-2	no	21.155	28.207	EPSD	GDSC;CCLE	26.151	Gain
CMGC_CDK_CDK8_CDK8_ST	Q01094	E2F1	P49336	CDK8	S403	A408T	408	Missense	distal	5	no	31.917	32.075	EPSD	GDSC;CCLE	26.151	Up-regulation
CMGC_CDK_CDK8_CDK8_ST	P51946	CCNH	P49336	CDK8	S5	Q7E	7	Missense	proximal	2	no	34.219	33.322	PhosphoSitePlus;EPSD	GDSC;CCLE	26.151	Down-regulation
CMGC_CDK_CDK8_CDK8_ST	P51946	CCNH	P49336	CDK8	S121	P123L	123	Missense	proximal	2	no	26.372	28.443	EPSD	GDSC;CCLE	26.151	Up-regulation
CMGC_CDK_CDK8_CDK8_ST	P51946	CCNH	P49336	CDK8	S132	G135E	135	Missense	distal	3	no	31.091	33.075	EPSD	GDSC;CCLE	26.151	Up-regulation
TK_Fak_PTK2_Y	Q9H5V8	CDCP1	Q05397	PTK2	Y806	Y806C	806	Missense	central	0	yes	0.000	0.000	EPSD	GDSC;CCLE	0.000	Loss
TK_Fak_PTK2_Y	Q99961	SH3GL1	Q05397	PTK2	Y315	Y315*	315	Missense	central	0	yes	0.000	0.000	PhosphoSitePlus	GDSC	0.000	Loss
TK_Fak_PTK2_Y	P63000	RAC1	Q05397	PTK2	Y32	Y32C	32	Missense	central	0	yes	0.000	0.000	EPSD	GDSC;CCLE	0.000	Loss
TK_Fak_PTK2_Y	P63000	RAC1	Q05397	PTK2	Y64	Y64H	64	Missense	central	0	yes	0.000	0.000	PhosphoSitePlus	GDSC;CCLE	0.000	Loss
AGC_RSK_RSKp90_RPS6KA1_ST	O95071	UBR5	Q15418	RPS6KA1	S115	W112*	112	Missense	distal	-3	no	1.788	1.793	EPSD	GDSC	1.787	Up-regulation
AGC_RSK_RSKp90_RPS6KA1_ST	O95071	UBR5	Q15418	RPS6KA1	S305	R309C	309	Missense	distal	4	no	2.894	2.909	EPSD	GDSC;CCLE	1.787	Up-regulation
AGC_RSK_RSKp90_RPS6KA1_ST	O95071	UBR5	Q15418	RPS6KA1	S636	M629T	629	Missense	distal	-7	no	1.931	1.919	EPSD	GDSC	1.787	Down-regulation
AGC_RSK_RSKp90_RPS6KA1_ST	O95071	UBR5	Q15418	RPS6KA1	S636	R635Q	635	Missense	proximal	-1	no	1.931	2.065	EPSD	GDSC	1.787	Up-regulation
AGC_RSK_RSKp90_RPS6KA1_ST	O95071	UBR5	Q15418	RPS6KA1	T1115	M1114T	1114	Missense	proximal	-1	no	1.869	1.893	EPSD	GDSC;CCLE	1.787	Up-regulation
AGC_RSK_RSKp90_RPS6KA1_ST	O95071	UBR5	Q15418	RPS6KA1	S1119	M1114T	1114	Missense	distal	-5	no	2.058	2.217	EPSD	GDSC;CCLE	1.787	Up-regulation
AGC_RSK_RSKp90_RPS6KA1_ST	O95071	UBR5	Q15418	RPS6KA1	T1306	R1304*	1304	Missense	proximal	-2	no	2.726	2.810	EPSD	GDSC	1.787	Up-regulation
AGC_RSK_RSKp90_RPS6KA1_ST	O95071	UBR5	Q15418	RPS6KA1	T1404	V1406M	1406	Missense	proximal	2	no	3.233	3.004	EPSD	GDSC;CCLE	1.787	Down-regulation
AGC_RSK_RSKp90_RPS6KA1_ST	O95071	UBR5	Q15418	RPS6KA1	T1404	D1399H	1399	Missense	distal	-5	no	3.233	3.060	EPSD	GDSC	1.787	Down-regulation
AGC_RSK_RSKp90_RPS6KA1_ST	O95071	UBR5	Q15418	RPS6KA1	S1549	P1543L	1543	Missense	distal	-6	no	3.013	3.172	EPSD	GDSC	1.787	Up-regulation
AGC_RSK_RSKp90_RPS6KA1_ST	O95071	UBR5	Q15418	RPS6KA1	T1699	N1705S	1705	Missense	distal	6	no	1.913	1.851	EPSD	GDSC	1.787	Down-regulation
AGC_RSK_RSKp90_RPS6KA1_ST	O95071	UBR5	Q15418	RPS6KA1	S1733	A1738V	1738	Missense	distal	5	no	1.950	2.035	EPSD	GDSC;CCLE	1.787	Up-regulation
AGC_RSK_RSKp90_RPS6KA1_ST	O95071	UBR5	Q15418	RPS6KA1	T1734	A1738V	1738	Missense	distal	4	no	1.862	1.813	EPSD	GDSC;CCLE	1.787	Down-regulation
AGC_RSK_RSKp90_RPS6KA1_ST	O95071	UBR5	Q15418	RPS6KA1	S2241	Q2236L	2236	Missense	distal	-5	no	2.102	2.154	EPSD	GDSC	1.787	Up-regulation
AGC_RSK_RSKp90_RPS6KA1_ST	O95071	UBR5	Q15418	RPS6KA1	S2437	R2439S	2439	Missense	proximal	2	no	2.475	2.323	EPSD	GDSC;CCLE	1.787	Down-regulation
AGC_RSK_RSKp90_RPS6KA1_ST	O95071	UBR5	Q15418	RPS6KA1	S2470	E2476A	2476	Missense	distal	6	no	2.581	2.377	EPSD	GDSC;CCLE	1.787	Down-regulation
AGC_RSK_RSKp90_RPS6KA1_ST	Q13164	MAPK7	Q15418	RPS6KA1	S720	E723D	723	Missense	distal	3	no	2.079	2.087	EPSD	GDSC;CCLE	1.787	Up-regulation
AGC_RSK_RSKp90_RPS6KA1_ST	O60343	TBC1D4	Q15418	RPS6KA1	S44	T50N	50	Missense	distal	6	no	2.694	2.903	EPSD	GDSC	1.787	Up-regulation
AGC_RSK_RSKp90_RPS6KA1_ST	O60343	TBC1D4	Q15418	RPS6KA1	T568	K564N	564	Missense	distal	-4	no	1.990	1.807	EPSD;PhosphoSitePlus	GDSC;CCLE	1.787	Down-regulation
AGC_RSK_RSKp90_RPS6KA1_ST	O60343	TBC1D4	Q15418	RPS6KA1	T568	K564R	564	Missense	distal	-4	no	1.990	2.016	EPSD;PhosphoSitePlus	GDSC	1.787	Up-regulation
AGC_RSK_RSKp90_RPS6KA1_ST	O60343	TBC1D4	Q15418	RPS6KA1	T811	P807T	807	Missense	distal	-4	no	2.128	2.045	EPSD	GDSC;CCLE	1.787	Down-regulation
AGC_RSK_RSKp90_RPS6KA1_ST	O60343	TBC1D4	Q15418	RPS6KA1	S1207	S1207N	1207	Missense	central	0	yes	1.857	0.000	EPSD	GDSC;CCLE	1.787	Loss
AGC_RSK_RSKp90_RPS6KA1_ST	Q92934	BAD	Q15418	RPS6KA1	S34	D29N	29	Missense	distal	-5	no	1.868	1.892	EPSD	GDSC	1.787	Up-regulation
AGC_RSK_RSKp90_RPS6KA1_ST	Q92934	BAD	Q15418	RPS6KA1	S124	L129F	129	Missense	distal	5	no	2.480	2.487	EPSD	GDSC	1.787	Up-regulation
AGC_RSK_RSKp90_RPS6KA1_ST	Q8IX03	WWC1	Q15418	RPS6KA1	S947	R941Q	941	Missense	distal	-6	no	1.558	1.944	PhosphoSitePlus;EPSD	GDSC	1.787	Gain
AGC_RSK_RSKp90_RPS6KA1_ST	Q8IX03	WWC1	Q15418	RPS6KA1	S974	R972W	972	Missense	proximal	-2	no	1.905	1.977	EPSD	GDSC;CCLE	1.787	Up-regulation
AGC_RSK_RSKp90_RPS6KA1_ST	Q8N122	RPTOR	Q15418	RPS6KA1	T126	P125S	125	Missense	proximal	-1	no	2.082	2.099	EPSD	GDSC;CCLE	1.787	Up-regulation
AGC_RSK_RSKp90_RPS6KA1_ST	Q8N122	RPTOR	Q15418	RPS6KA1	S696	L694F	694	Missense	proximal	-2	no	2.534	2.542	EPSD	GDSC;CCLE	1.787	Up-regulation
AGC_RSK_RSKp90_RPS6KA1_ST	P16220	CREB1	Q15418	RPS6KA1	T104	S111L	111	Missense	distal	7	no	2.270	2.278	EPSD	GDSC;CCLE	1.787	Up-regulation
AGC_RSK_RSKp90_RPS6KA1_ST	Q2M1Z3	ARHGAP31	Q15418	RPS6KA1	S382	S382F	382	Missense	central	0	yes	2.612	0.000	EPSD	GDSC	1.787	Loss
AGC_RSK_RSKp90_RPS6KA1_ST	Q2M1Z3	ARHGAP31	Q15418	RPS6KA1	S593	E586D	586	Missense	distal	-7	no	2.003	1.995	EPSD	GDSC;CCLE	1.787	Down-regulation
AGC_RSK_RSKp90_RPS6KA1_ST	Q2M1Z3	ARHGAP31	Q15418	RPS6KA1	S680	Q683H	683	Missense	distal	3	no	1.981	2.030	EPSD	GDSC	1.787	Up-regulation
AGC_RSK_RSKp90_RPS6KA1_ST	Q2M1Z3	ARHGAP31	Q15418	RPS6KA1	S680	T679I	679	Missense	proximal	-1	no	1.981	1.748	EPSD	GDSC	1.787	Loss
AGC_RSK_RSKp90_RPS6KA1_ST	Q2M1Z3	ARHGAP31	Q15418	RPS6KA1	S696	E697V	697	Missense	proximal	1	no	1.894	1.831	EPSD	GDSC;CCLE	1.787	Down-regulation
AGC_RSK_RSKp90_RPS6KA1_ST	Q2M1Z3	ARHGAP31	Q15418	RPS6KA1	S957	T960M	960	Missense	distal	3	no	1.879	1.773	EPSD	GDSC;CCLE	1.787	Loss
AGC_RSK_RSKp90_RPS6KA1_ST	Q2M1Z3	ARHGAP31	Q15418	RPS6KA1	S972	V969L	969	Missense	distal	-3	no	2.080	2.735	EPSD	GDSC;CCLE	1.787	Up-regulation
AGC_RSK_RSKp90_RPS6KA1_ST	Q2M1Z3	ARHGAP31	Q15418	RPS6KA1	S1036	N1031S	1031	Missense	distal	-5	no	1.987	1.727	EPSD	GDSC;CCLE	1.787	Loss
AGC_RSK_RSKp90_RPS6KA1_ST	Q2M1Z3	ARHGAP31	Q15418	RPS6KA1	S1054	S1053N	1053	Missense	proximal	-1	no	3.090	3.030	EPSD	GDSC;CCLE	1.787	Down-regulation
AGC_RSK_RSKp90_RPS6KA1_ST	Q2M1Z3	ARHGAP31	Q15418	RPS6KA1	S1184	M1191V	1191	Missense	distal	7	no	1.638	1.821	EPSD	GDSC;CCLE	1.787	Gain
AGC_RSK_RSKp90_RPS6KA1_ST	Q2M1Z3	ARHGAP31	Q15418	RPS6KA1	S1384	P1385T	1385	Missense	proximal	1	no	1.771	1.799	EPSD	GDSC	1.787	Gain
AGC_RSK_RSKp90_RPS6KA1_ST	Q2M1Z3	ARHGAP31	Q15418	RPS6KA1	T1396	W1397*	1397	Missense	proximal	1	no	3.378	3.331	EPSD	GDSC	1.787	Down-regulation
AGC_RSK_RSKp90_RPS6KA1_ST	P49841	GSK3B	Q15418	RPS6KA1	T324	R319*	319	Missense	distal	-5	no	2.230	2.331	EPSD	GDSC	1.787	Up-regulation
AGC_RSK_RSKp90_RPS6KA1_ST	P30305	CDC25B	Q15418	RPS6KA1	S91	R93Q	93	Missense	proximal	2	no	2.641	2.406	EPSD	GDSC;CCLE	1.787	Down-regulation
AGC_RSK_RSKp90_RPS6KA1_ST	P30305	CDC25B	Q15418	RPS6KA1	S91	S89T	89	Missense	proximal	-2	no	2.641	2.682	EPSD	GDSC;CCLE	1.787	Up-regulation
AGC_RSK_RSKp90_RPS6KA1_ST	P30307	CDC25C	Q15418	RPS6KA1	S38	E34Q	34	Missense	distal	-4	no	3.201	3.119	EPSD	GDSC;CCLE	1.787	Down-regulation
AGC_RSK_RSKp90_RPS6KA1_ST	P30307	CDC25C	Q15418	RPS6KA1	S75	G80R	80	Missense	distal	5	no	1.392	1.830	EPSD	GDSC;CCLE	1.787	Gain
AGC_RSK_RSKp90_RPS6KA1_ST	Q8TB45	DEPTOR	Q15418	RPS6KA1	S235	H242N	242	Missense	distal	7	no	1.780	1.947	EPSD	GDSC	1.787	Gain
AGC_RSK_RSKp90_RPS6KA1_ST	Q8TB45	DEPTOR	Q15418	RPS6KA1	S235	Q239K	239	Missense	distal	4	no	1.780	1.808	EPSD	GDSC;CCLE	1.787	Gain
AGC_RSK_RSKp90_RPS6KA1_ST	P49815	TSC2	Q15418	RPS6KA1	S609	A614T	614	Missense	distal	5	no	1.958	1.910	EPSD	GDSC	1.787	Down-regulation
AGC_RSK_RSKp90_RPS6KA1_ST	P49815	TSC2	Q15418	RPS6KA1	S609	I606V	606	Missense	distal	-3	no	1.958	1.514	EPSD	GDSC;CCLE	1.787	Loss
AGC_RSK_RSKp90_RPS6KA1_ST	P49815	TSC2	Q15418	RPS6KA1	S1466	G1472D	1472	Missense	distal	6	no	3.004	2.954	EPSD	GDSC;CCLE	1.787	Down-regulation
AGC_RSK_RSKp90_RPS6KA1_ST	O00418	EEF2K	Q15418	RPS6KA1	S71	Y69H	69	Missense	proximal	-2	no	1.969	1.976	EPSD	GDSC;CCLE	1.787	Up-regulation
AGC_RSK_RSKp90_RPS6KA1_ST	O00418	EEF2K	Q15418	RPS6KA1	S478	V481I	481	Missense	distal	3	no	1.938	1.951	EPSD	GDSC	1.787	Up-regulation
AGC_RSK_RSKp90_RPS6KA1_ST	O00418	EEF2K	Q15418	RPS6KA1	S478	C482W	482	Missense	distal	4	no	1.938	1.934	EPSD	GDSC;CCLE	1.787	Down-regulation
AGC_RSK_RSKp90_RPS6KA1_ST	P03372	ESR1	Q15418	RPS6KA1	T485	D480G	480	Missense	distal	-5	no	1.859	1.802	EPSD	GDSC;CCLE	1.787	Down-regulation
AGC_RSK_RSKp90_RPS6KA1_ST	O14745	SLC9A3R1	Q15418	RPS6KA1	T156	R151W	151	Missense	distal	-5	no	1.780	1.922	PhosphoSitePlus	GDSC	1.787	Gain
AGC_RSK_RSKp90_RPS6KA1_ST	P62753	RPS6	Q15418	RPS6KA1	S107	I101S	101	Missense	distal	-6	no	2.242	1.982	EPSD	GDSC;CCLE	1.787	Down-regulation
AGC_RSK_RSKp90_RPS6KA1_ST	P62753	RPS6	Q15418	RPS6KA1	S247	S242F	242	Missense	distal	-5	no	1.960	2.087	EPSD	GDSC	1.787	Up-regulation
AGC_RSK_RSKp90_RPS6KA1_ST	P21333	FLNA	Q15418	RPS6KA1	S204	A206V	206	Missense	proximal	2	no	1.504	1.812	EPSD	GDSC;CCLE	1.787	Gain
AGC_RSK_RSKp90_RPS6KA1_ST	P21333	FLNA	Q15418	RPS6KA1	S481	C478Y	478	Missense	distal	-3	no	1.649	1.803	EPSD	GDSC;CCLE	1.787	Gain
AGC_RSK_RSKp90_RPS6KA1_ST	P21333	FLNA	Q15418	RPS6KA1	T685	G681R	681	Missense	distal	-4	no	1.908	2.028	EPSD	GDSC;CCLE	1.787	Up-regulation
AGC_RSK_RSKp90_RPS6KA1_ST	P21333	FLNA	Q15418	RPS6KA1	T1427	G1420S	1420	Missense	distal	-7	no	2.803	2.855	EPSD	GDSC;CCLE	1.787	Up-regulation
AGC_RSK_RSKp90_RPS6KA1_ST	P21333	FLNA	Q15418	RPS6KA1	T1427	V1426I	1426	Missense	proximal	-1	no	2.803	2.535	EPSD	GDSC;CCLE	1.787	Down-regulation
AGC_RSK_RSKp90_RPS6KA1_ST	P21333	FLNA	Q15418	RPS6KA1	T1558	A1562V	1562	Missense	distal	4	no	2.077	2.027	EPSD	GDSC;CCLE	1.787	Down-regulation
AGC_RSK_RSKp90_RPS6KA1_ST	P21333	FLNA	Q15418	RPS6KA1	S1630	R1633P	1633	Missense	distal	3	no	1.891	2.000	EPSD	GDSC;CCLE	1.787	Up-regulation
AGC_RSK_RSKp90_RPS6KA1_ST	P21333	FLNA	Q15418	RPS6KA1	S1812	A1816V	1816	Missense	distal	4	no	2.967	2.917	EPSD	GDSC;CCLE	1.787	Down-regulation
AGC_RSK_RSKp90_RPS6KA1_ST	P21333	FLNA	Q15418	RPS6KA1	S1812	R1809Q	1809	Missense	distal	-3	no	2.967	2.557	EPSD	GDSC;CCLE	1.787	Down-regulation
AGC_RSK_RSKp90_RPS6KA1_ST	P21333	FLNA	Q15418	RPS6KA1	S1991	V1988I	1988	Missense	distal	-3	no	2.402	2.847	EPSD	GDSC	1.787	Up-regulation
AGC_RSK_RSKp90_RPS6KA1_ST	P21333	FLNA	Q15418	RPS6KA1	T2627	V2629L	2629	Missense	proximal	2	no	2.122	2.002	EPSD	GDSC;CCLE	1.787	Down-regulation
AGC_RSK_RSKp90_RPS6KA1_ST	Q53EL6	PDCD4	Q15418	RPS6KA1	S71	R69W	69	Missense	proximal	-2	no	1.924	1.996	EPSD	GDSC	1.787	Up-regulation
AGC_RSK_RSKp90_RPS6KA1_ST	Q53EL6	PDCD4	Q15418	RPS6KA1	S313	G307R	307	Missense	distal	-6	no	2.077	1.169	EPSD	GDSC	1.787	Loss
AGC_RSK_RSKp90_RPS6KA1_ST	Q53EL6	PDCD4	Q15418	RPS6KA1	S393	D399H	399	Missense	distal	6	no	1.799	1.840	EPSD	GDSC;CCLE	1.787	Up-regulation
AGC_RSK_RSKp90_RPS6KA1_ST	Q53EL6	PDCD4	Q15418	RPS6KA1	S393	S394C	394	Missense	proximal	1	no	1.799	1.830	EPSD	GDSC;CCLE	1.787	Up-regulation
AGC_RSK_RSKp90_RPS6KA1_ST	Q07889	SOS1	Q15418	RPS6KA1	S1166	M1172I	1172	Missense	distal	6	no	1.813	1.802	EPSD	GDSC;CCLE	1.787	Down-regulation
AGC_RSK_RSKp90_RPS6KA1_ST	P13796	LCP1	Q15418	RPS6KA1	S474	G480E	480	Missense	distal	6	no	2.365	2.484	EPSD	GDSC	1.787	Up-regulation
AGC_RSK_RSKp90_RPS6KA1_ST	Q92882	OSTF1	Q15418	RPS6KA1	T195	R199*	199	Missense	distal	4	no	1.937	1.939	EPSD	GDSC	1.787	Up-regulation
AGC_RSK_RSKp90_RPS6KA1_ST	P30304	CDC25A	Q15418	RPS6KA1	S320	A319V	319	Missense	proximal	-1	no	1.986	2.207	EPSD	GDSC;CCLE	1.787	Up-regulation
AGC_RSK_RSKp90_RPS6KA1_ST	P30304	CDC25A	Q15418	RPS6KA1	S320	Q314*	314	Missense	distal	-6	no	1.986	1.922	EPSD	GDSC	1.787	Down-regulation
AGC_RSK_RSKp90_RPS6KA1_ST	P60983	GMFB	Q15418	RPS6KA1	S72	D78H	78	Missense	distal	6	no	2.492	2.533	EPSD	GDSC;CCLE	1.787	Up-regulation
AGC_RSK_RSKp90_RPS6KA1_ST	P60983	GMFB	Q15418	RPS6KA1	S72	Q65*	65	Missense	distal	-7	no	2.492	2.487	EPSD	GDSC	1.787	Down-regulation
AGC_RSK_RSKp90_RPS6KA1_ST	P60983	GMFB	Q15418	RPS6KA1	S72	F68L	68	Missense	distal	-4	no	2.492	2.586	EPSD	GDSC;CCLE	1.787	Up-regulation
AGC_RSK_RSKp90_RPS6KA1_ST	P29317	EPHA2	Q15418	RPS6KA1	S636	S636L	636	Missense	central	0	yes	2.293	0.000	EPSD	GDSC;CCLE	1.787	Loss
AGC_RSK_RSKp90_RPS6KA1_ST	P29317	EPHA2	Q15418	RPS6KA1	S901	P896R	896	Missense	distal	-5	no	1.961	1.802	EPSD	GDSC;CCLE	1.787	Down-regulation
AGC_RSK_RSKp90_RPS6KA1_ST	P23588	EIF4B	Q15418	RPS6KA1	S406	R401G	401	Missense	distal	-5	no	1.692	1.896	EPSD	GDSC;CCLE	1.787	Gain
AGC_RSK_RSKp90_RPS6KA1_ST	P16144	ITGB4	Q15418	RPS6KA1	T168	T168A	168	Missense	central	0	yes	1.859	0.000	EPSD	GDSC	1.787	Loss
AGC_RSK_RSKp90_RPS6KA1_ST	P16144	ITGB4	Q15418	RPS6KA1	T1455	D1448G	1448	Missense	distal	-7	no	1.912	1.858	EPSD	GDSC;CCLE	1.787	Down-regulation
AGC_RSK_RSKp90_RPS6KA1_ST	Q9HC62	SENP2	Q15418	RPS6KA1	T369	E373G	373	Missense	distal	4	no	2.495	2.517	PhosphoSitePlus	GDSC;CCLE	1.787	Up-regulation
AGC_RSK_RSKp90_RPS6KA1_ST	Q96RK0	CIC	Q15418	RPS6KA1	S502	P509A	509	Missense	distal	7	no	1.897	1.747	EPSD	GDSC;CCLE	1.787	Loss
AGC_RSK_RSKp90_RPS6KA1_ST	Q96RK0	CIC	Q15418	RPS6KA1	T567	L571I	571	Missense	distal	4	no	1.902	1.874	EPSD	GDSC;CCLE	1.787	Down-regulation
AGC_RSK_RSKp90_RPS6KA1_ST	Q96RK0	CIC	Q15418	RPS6KA1	S585	A587V	587	Missense	proximal	2	no	2.007	2.315	EPSD	GDSC;CCLE	1.787	Up-regulation
AGC_RSK_RSKp90_RPS6KA1_ST	P25963	NFKBIA	Q15418	RPS6KA1	S283	L277P	277	Missense	distal	-6	no	3.859	3.700	EPSD	GDSC	1.787	Down-regulation
TK_PDGFR_PDGFRA_Y	P16234	PDGFRA	P16234	PDGFRA	Y572	P577T	577	Missense	distal	5	no	13.678	12.927	EPSD;PhosphoSitePlus	GDSC;CCLE	8.840	Down-regulation
TK_PDGFR_PDGFRA_Y	P16234	PDGFRA	P16234	PDGFRA	Y574	P577T	577	Missense	distal	3	no	13.819	12.463	EPSD;PhosphoSitePlus	GDSC;CCLE	8.840	Down-regulation
TK_PDGFR_PDGFRA_Y	P16234	PDGFRA	P16234	PDGFRA	Y720	E715K	715	Missense	distal	-5	no	14.620	15.414	EPSD	GDSC;CCLE	8.840	Up-regulation
TK_PDGFR_PDGFRA_Y	P16234	PDGFRA	P16234	PDGFRA	Y731	D730A	730	Missense	proximal	-1	no	14.394	14.407	EPSD	GDSC;CCLE	8.840	Up-regulation
TK_PDGFR_PDGFRA_Y	P16234	PDGFRA	P16234	PDGFRA	Y849	N848I	848	Missense	proximal	-1	no	9.824	9.808	EPSD	GDSC;CCLE	8.840	Down-regulation
TK_PDGFR_PDGFRA_Y	Q9P219	CCDC88C	P16234	PDGFRA	Y1395	K1400Q	1400	Missense	distal	5	no	9.006	10.543	EPSD	GDSC	8.840	Up-regulation
AGC_GRK_BARK_GRK2_ST	P35241	RDX	P25098	GRK2	T564	K563N	563	Missense	proximal	-1	no	167.189	179.923	PhosphoSitePlus	GDSC;CCLE	128.034	Up-regulation
AGC_GRK_BARK_GRK2_ST	P35241	RDX	P25098	GRK2	T573	I577V	577	Missense	distal	4	no	126.152	132.851	EPSD	GDSC;CCLE	128.034	Gain
AGC_GRK_BARK_GRK2_ST	P15311	EZR	P25098	GRK2	T548	N545S	545	Missense	distal	-3	no	143.837	133.489	EPSD	GDSC;CCLE	128.034	Down-regulation
AGC_GRK_BARK_GRK2_ST	P15311	EZR	P25098	GRK2	T548	H549R	549	Missense	proximal	1	no	143.837	140.277	EPSD	GDSC;CCLE	128.034	Down-regulation
AGC_GRK_BARK_GRK2_ST	P15311	EZR	P25098	GRK2	T548	D551H	551	Missense	distal	3	no	143.837	145.753	EPSD	GDSC;CCLE	128.034	Up-regulation
AGC_GRK_BARK_GRK2_ST	P15311	EZR	P25098	GRK2	T576	I580V	580	Missense	distal	4	no	131.411	138.110	EPSD	GDSC;CCLE	128.034	Up-regulation
AGC_GRK_BARK_GRK2_ST	P07550	ADRB2	P25098	GRK2	S396	G403R	403	Missense	distal	7	no	164.934	164.844	PhosphoSitePlus;EPSD	GDSC;CCLE	128.034	Down-regulation
AGC_GRK_BARK_GRK2_ST	P07550	ADRB2	P25098	GRK2	S401	G403R	403	Missense	proximal	2	no	165.208	165.748	EPSD;PhosphoSitePlus	GDSC;CCLE	128.034	Up-regulation
AGC_GRK_BARK_GRK2_ST	P07550	ADRB2	P25098	GRK2	S407	G403R	403	Missense	distal	-4	no	147.963	149.820	EPSD;PhosphoSitePlus	GDSC;CCLE	128.034	Up-regulation
AGC_GRK_BARK_GRK2_ST	P07550	ADRB2	P25098	GRK2	T408	G403R	403	Missense	distal	-5	no	132.393	134.948	EPSD	GDSC;CCLE	128.034	Up-regulation
AGC_GRK_BARK_GRK2_ST	Q14940	SLC9A5	P25098	GRK2	S741	G736R	736	Missense	distal	-5	no	142.504	145.059	EPSD	GDSC	128.034	Up-regulation
AGC_GRK_BARK_GRK2_ST	P08172	CHRM2	P25098	GRK2	S232	Q228*	228	Missense	distal	-4	no	135.315	131.901	EPSD;PhosphoSitePlus	GDSC	128.034	Down-regulation
AGC_GRK_BARK_GRK2_ST	P08172	CHRM2	P25098	GRK2	S234	Q228*	228	Missense	distal	-6	no	135.010	129.539	EPSD;PhosphoSitePlus	GDSC	128.034	Down-regulation
AGC_GRK_BARK_GRK2_ST	P08172	CHRM2	P25098	GRK2	S234	I240L	240	Missense	distal	6	no	135.010	133.000	EPSD;PhosphoSitePlus	GDSC;CCLE	128.034	Down-regulation
AGC_GRK_BARK_GRK2_ST	P08172	CHRM2	P25098	GRK2	S250	E256A	256	Missense	distal	6	no	154.968	152.762	EPSD;PhosphoSitePlus	GDSC;CCLE	128.034	Down-regulation
AGC_GRK_BARK_GRK2_ST	P08172	CHRM2	P25098	GRK2	S251	E256A	256	Missense	distal	5	no	143.627	139.616	EPSD;PhosphoSitePlus	GDSC;CCLE	128.034	Down-regulation
AGC_GRK_BARK_GRK2_ST	P21731	TBXA2R	P25098	GRK2	S324	S324N	324	Missense	central	0	yes	131.962	0.000	EPSD	GDSC	128.034	Loss
AGC_GRK_BARK_GRK2_ST	P21731	TBXA2R	P25098	GRK2	S329	S324N	324	Missense	distal	-5	no	136.048	135.556	EPSD	GDSC	128.034	Down-regulation
AGC_GRK_BARK_GRK2_ST	P21731	TBXA2R	P25098	GRK2	S331	S324N	324	Missense	distal	-7	no	159.561	164.429	EPSD	GDSC	128.034	Up-regulation
AGC_GRK_BARK_GRK2_ST	O95398	RAPGEF3	P25098	GRK2	S150	S148F	148	Missense	proximal	-2	no	133.869	112.593	EPSD	GDSC;CCLE	128.034	Loss
AGC_GRK_BARK_GRK2_ST	O95398	RAPGEF3	P25098	GRK2	S150	V152A	152	Missense	proximal	2	no	133.869	126.946	EPSD	GDSC;CCLE	128.034	Loss
AGC_GRK_BARK_GRK2_ST	O95398	RAPGEF3	P25098	GRK2	T380	N384I	384	Missense	distal	4	no	128.646	126.567	EPSD	GDSC	128.034	Loss
AGC_GRK_BARK_GRK2_ST	O95398	RAPGEF3	P25098	GRK2	S915	R919*	919	Missense	distal	4	no	141.113	137.850	EPSD	GDSC	128.034	Down-regulation
AGC_GRK_BARK_GRK2_ST	O95398	RAPGEF3	P25098	GRK2	S918	R919*	919	Missense	proximal	1	no	129.954	125.180	EPSD	GDSC	128.034	Loss
AGC_GRK_BARK_GRK2_ST	P09497	CLTB	P25098	GRK2	S217	Q224E	224	Missense	distal	7	no	161.415	161.743	EPSD	GDSC;CCLE	128.034	Up-regulation
AGC_GRK_BARK_GRK2_ST	P09497	CLTB	P25098	GRK2	S221	Q224E	224	Missense	distal	3	no	127.893	134.362	EPSD	GDSC;CCLE	128.034	Gain
AGC_GRK_BARK_GRK2_ST	P09497	CLTB	P25098	GRK2	T225	Q224E	224	Missense	proximal	-1	no	137.440	140.562	EPSD	GDSC;CCLE	128.034	Up-regulation
AGC_GRK_BARK_GRK2_ST	P09497	CLTB	P25098	GRK2	S228	Q224E	224	Missense	distal	-4	no	150.885	156.117	EPSD	GDSC;CCLE	128.034	Up-regulation
AGC_GRK_BARK_GRK2_ST	P26038	MSN	P25098	GRK2	T510	R517H	517	Missense	distal	7	no	128.394	129.532	EPSD	GDSC;CCLE	128.034	Up-regulation
AGC_GRK_BARK_GRK2_ST	Q96A54	ADIPOR1	P25098	GRK2	S7	S3C	3	Missense	distal	-4	no	146.400	142.255	EPSD;PhosphoSitePlus	GDSC;CCLE	128.034	Down-regulation
AGC_GRK_BARK_GRK2_ST	Q96A54	ADIPOR1	P25098	GRK2	T24	A17T	17	Missense	distal	-7	no	149.710	149.686	PhosphoSitePlus;EPSD	GDSC;CCLE	128.034	Down-regulation
AGC_GRK_BARK_GRK2_ST	Q15796	SMAD2	P25098	GRK2	S460	S464*	464	Missense	distal	4	no	143.401	141.204	EPSD	GDSC	128.034	Down-regulation
AGC_GRK_BARK_GRK2_ST	Q15796	SMAD2	P25098	GRK2	S467	S464*	464	Missense	distal	-3	no	153.772	154.021	EPSD	GDSC	128.034	Up-regulation
AGC_GRK_BARK_GRK2_ST	P08069	IGF1R	P25098	GRK2	S752	T758M	758	Missense	distal	6	no	142.535	142.764	EPSD	GDSC;CCLE	128.034	Up-regulation
AGC_GRK_BARK_GRK2_ST	P37840	SNCA	P25098	GRK2	S129	M127I	127	Missense	proximal	-2	no	184.693	178.042	PhosphoSitePlus	GDSC	128.034	Down-regulation
AGC_GRK_BARK_GRK2_ST	P37840	SNCA	P25098	GRK2	S129	E130G	130	Missense	proximal	1	no	184.693	167.498	PhosphoSitePlus	GDSC	128.034	Down-regulation
STE_STE11_MEKK2_MAP3K2_ST	P35222	CTNNB1	Q9Y2U5	MAP3K2	S675	Y670*	670	Missense	distal	-5	no	4.783	4.589	PhosphoSitePlus	GDSC	2.079	Down-regulation
STE_STE7_MEK1_MAP2K2_ST	P27361	MAPK3	P36507	MAP2K2	T202	E203D	203	Missense	proximal	1	no	11.021	10.142	PhosphoSitePlus;EPSD	GDSC;CCLE	1.900	Down-regulation
STE_STE7_MEK1_MAP2K2_ST	P05787	KRT8	P36507	MAP2K2	S71	L76R	76	Missense	distal	5	no	2.947	3.089	EPSD	GDSC;CCLE	1.900	Up-regulation
STE_STE7_MEK1_MAP2K2_ST	P05787	KRT8	P36507	MAP2K2	S74	L76R	76	Missense	proximal	2	no	8.868	8.849	PhosphoSitePlus	GDSC;CCLE	1.900	Down-regulation
STE_STE7_MEK1_MAP2K2_ST	P05787	KRT8	P36507	MAP2K2	T131	A132T	132	Missense	proximal	1	no	1.990	1.951	EPSD	GDSC;CCLE	1.900	Down-regulation
STE_STE7_MEK1_MAP2K2_ST	P05787	KRT8	P36507	MAP2K2	S450	T455A	455	Missense	distal	5	no	1.967	1.675	EPSD	GDSC	1.900	Loss
TK_Jak_JAK3_Y	O14939	PLD2	P52333	JAK3	Y296	S294N	294	Missense	proximal	-2	no	96.737	94.280	EPSD	GDSC;CCLE	65.077	Down-regulation
TK_Jak_JAK3_Y	O95644	NFATC1	P52333	JAK3	Y268	P275L	275	Missense	distal	7	no	81.913	81.480	EPSD	GDSC	65.077	Down-regulation
TK_Jak_JAK3_Y	P52333	JAK3	P52333	JAK3	Y506	S504C	504	Missense	proximal	-2	no	88.067	82.479	EPSD	GDSC;CCLE	65.077	Down-regulation
TK_Jak_JAK3_Y	P52333	JAK3	P52333	JAK3	Y939	M937T	937	Missense	proximal	-2	no	106.715	106.550	EPSD;PhosphoSitePlus	GDSC;CCLE	65.077	Down-regulation
TK_Jak_JAK3_Y	P42229	STAT5A	P52333	JAK3	Y694	P697L	697	Missense	distal	3	no	107.279	111.809	PhosphoSitePlus	GDSC	65.077	Up-regulation
TK_Jak_JAK3_Y	Q96LC7	SIGLEC10	P52333	JAK3	Y597	I594M	594	Missense	distal	-3	no	72.626	74.321	EPSD;PhosphoSitePlus	GDSC;CCLE	65.077	Up-regulation
TK_Jak_JAK3_Y	Q96LC7	SIGLEC10	P52333	JAK3	Y641	P644L	644	Missense	distal	3	no	85.795	90.325	EPSD	GDSC	65.077	Up-regulation
TK_Jak_JAK3_Y	Q96LC7	SIGLEC10	P52333	JAK3	Y667	L670F	670	Missense	distal	3	no	93.502	90.453	PhosphoSitePlus;EPSD	GDSC;CCLE	65.077	Down-regulation
TK_Jak_JAK3_Y	Q96LC7	SIGLEC10	P52333	JAK3	Y667	H666D	666	Missense	proximal	-1	no	93.502	110.402	PhosphoSitePlus;EPSD	GDSC	65.077	Up-regulation
TK_Jak_JAK3_Y	P35222	CTNNB1	P52333	JAK3	Y64	T59N	59	Missense	distal	-5	no	100.828	102.369	EPSD;PhosphoSitePlus	GDSC	65.077	Up-regulation
TK_Jak_JAK3_Y	P35222	CTNNB1	P52333	JAK3	Y142	A135V	135	Missense	distal	-7	no	58.814	65.531	EPSD	GDSC;CCLE	65.077	Gain
TK_Jak_JAK3_Y	Q15717	ELAVL1	P52333	JAK3	Y200	S197L	197	Missense	distal	-3	no	104.116	99.922	EPSD;PhosphoSitePlus	GDSC;CCLE	65.077	Down-regulation
TK_Tec_ITK_Y	Q08881	ITK	Q08881	ITK	Y180	V176A	176	Missense	distal	-4	no	18.295	18.836	PhosphoSitePlus	GDSC;CCLE	9.294	Up-regulation
TK_Tec_ITK_Y	Q08881	ITK	Q08881	ITK	Y182	V176A	176	Missense	distal	-6	no	9.788	10.335	EPSD	GDSC;CCLE	9.294	Up-regulation
TK_Tec_ITK_Y	P19174	PLCG1	Q08881	ITK	Y783	E785K	785	Missense	proximal	2	no	19.117	18.690	PhosphoSitePlus	GDSC;CCLE	9.294	Down-regulation
TK_Tec_ITK_Y	Q96LC7	SIGLEC10	Q08881	ITK	Y597	I594M	594	Missense	distal	-3	no	20.710	20.299	EPSD;PhosphoSitePlus	GDSC;CCLE	9.294	Down-regulation
TK_Tec_ITK_Y	Q96LC7	SIGLEC10	Q08881	ITK	Y641	P644L	644	Missense	distal	3	no	9.591	9.764	EPSD	GDSC	9.294	Up-regulation
TK_Tec_ITK_Y	Q96LC7	SIGLEC10	Q08881	ITK	Y667	L670F	670	Missense	distal	3	no	18.530	18.186	PhosphoSitePlus;EPSD	GDSC;CCLE	9.294	Down-regulation
TK_Tec_ITK_Y	Q96LC7	SIGLEC10	Q08881	ITK	Y667	H666D	666	Missense	proximal	-1	no	18.530	18.514	PhosphoSitePlus;EPSD	GDSC	9.294	Down-regulation
TK_Tec_ITK_Y	Q13094	LCP2	Q08881	ITK	Y380	Y380*	380	Missense	central	0	yes	12.813	0.000	EPSD	GDSC	9.294	Loss
TK_Tec_ITK_Y	Q13094	LCP2	Q08881	ITK	Y380	Y380H	380	Missense	central	0	yes	12.813	0.000	EPSD	GDSC;CCLE	9.294	Loss
TK_Csk_CSK_Y	P12931	SRC	P41240	CSK	Y530	Q529H	529	Missense	proximal	-1	no	115.622	103.703	PhosphoSitePlus;EPSD	GDSC;CCLE	33.668	Down-regulation
TK_Csk_CSK_Y	P07947	YES1	P41240	CSK	Y32	Y32C	32	Missense	central	0	yes	41.419	0.000	EPSD	GDSC	33.668	Loss
TK_Csk_CSK_Y	P08575	PTPRC	P41240	CSK	Y544	Y544*	544	Missense	central	0	yes	44.342	0.000	EPSD	GDSC	33.668	Loss
TK_Csk_CSK_Y	P08575	PTPRC	P41240	CSK	Y978	P977Q	977	Missense	proximal	-1	no	30.482	36.109	EPSD	GDSC;CCLE	33.668	Gain
TK_Csk_CSK_Y	P08575	PTPRC	P41240	CSK	Y1216	L1219P	1219	Missense	distal	3	no	48.230	48.779	PhosphoSitePlus	GDSC;CCLE	33.668	Up-regulation
TK_Csk_CSK_Y	P06241	FYN	P41240	CSK	Y531	E535K	535	Missense	distal	4	no	111.873	108.392	PhosphoSitePlus	GDSC;CCLE	33.668	Down-regulation
CMGC_MAPK_ERK5_MAPK7_ST	Q13164	MAPK7	Q13164	MAPK7	T28	H27Y	27	Missense	proximal	-1	no	108.435	108.492	EPSD;PhosphoSitePlus	GDSC;CCLE	81.800	Up-regulation
CMGC_MAPK_ERK5_MAPK7_ST	Q13164	MAPK7	Q13164	MAPK7	S472	A470T	470	Missense	proximal	-2	no	93.483	91.893	EPSD	GDSC	81.800	Down-regulation
CMGC_MAPK_ERK5_MAPK7_ST	Q13164	MAPK7	Q13164	MAPK7	S472	A478S	478	Missense	distal	6	no	93.483	92.762	EPSD	GDSC;CCLE	81.800	Down-regulation
CMGC_MAPK_ERK5_MAPK7_ST	Q13164	MAPK7	Q13164	MAPK7	S772	A779D	779	Missense	distal	7	no	107.012	107.971	EPSD;PhosphoSitePlus	GDSC;CCLE	81.800	Up-regulation
CMGC_MAPK_ERK5_MAPK7_ST	Q13164	MAPK7	Q13164	MAPK7	S774	A779D	779	Missense	distal	5	no	119.380	121.649	EPSD;PhosphoSitePlus	GDSC;CCLE	81.800	Up-regulation
CMGC_MAPK_ERK5_MAPK7_ST	Q13164	MAPK7	Q13164	MAPK7	S774	W781C	781	Missense	distal	7	no	119.380	116.266	EPSD;PhosphoSitePlus	GDSC;CCLE	81.800	Down-regulation
CMGC_MAPK_ERK5_MAPK7_ST	Q13164	MAPK7	Q13164	MAPK7	S776	A779D	779	Missense	distal	3	no	106.005	107.731	EPSD	GDSC;CCLE	81.800	Up-regulation
CMGC_MAPK_ERK5_MAPK7_ST	Q13164	MAPK7	Q13164	MAPK7	S776	W781C	781	Missense	distal	5	no	106.005	103.338	EPSD	GDSC;CCLE	81.800	Down-regulation
CMGC_MAPK_ERK5_MAPK7_ST	P01100	FOS	Q13164	MAPK7	T232	P233A	233	Missense	proximal	1	no	106.787	102.163	EPSD;PhosphoSitePlus	GDSC	81.800	Down-regulation
CMGC_MAPK_ERK5_MAPK7_ST	Q12959	DLG1	Q13164	MAPK7	S598	G604*	604	Missense	distal	6	no	88.380	84.943	EPSD	GDSC	81.800	Down-regulation
CMGC_MAPK_ERK5_MAPK7_ST	Q12959	DLG1	Q13164	MAPK7	S598	T595N	595	Missense	distal	-3	no	88.380	91.247	EPSD	GDSC;CCLE	81.800	Up-regulation
CMGC_MAPK_ERK5_MAPK7_ST	Q13163	MAP2K5	Q13164	MAPK7	S137	D138G	138	Missense	proximal	1	no	110.596	117.585	EPSD;PhosphoSitePlus	GDSC;CCLE	81.800	Up-regulation
CMGC_MAPK_ERK5_MAPK7_ST	Q13163	MAP2K5	Q13164	MAPK7	S137	S139*	139	Missense	proximal	2	no	110.596	100.318	EPSD;PhosphoSitePlus	GDSC	81.800	Down-regulation
CMGC_MAPK_ERK5_MAPK7_ST	Q13163	MAP2K5	Q13164	MAPK7	S142	D138G	138	Missense	distal	-4	no	107.084	104.858	PhosphoSitePlus;EPSD	GDSC;CCLE	81.800	Down-regulation
CMGC_MAPK_ERK5_MAPK7_ST	Q13163	MAP2K5	Q13164	MAPK7	S142	S139*	139	Missense	distal	-3	no	107.084	103.440	PhosphoSitePlus;EPSD	GDSC	81.800	Down-regulation
CMGC_MAPK_ERK5_MAPK7_ST	Q13163	MAP2K5	Q13164	MAPK7	S144	D138G	138	Missense	distal	-6	no	86.749	91.331	EPSD	GDSC;CCLE	81.800	Up-regulation
CMGC_MAPK_ERK5_MAPK7_ST	Q13163	MAP2K5	Q13164	MAPK7	S144	S139*	139	Missense	distal	-5	no	86.749	83.890	EPSD	GDSC	81.800	Down-regulation
CMGC_MAPK_ERK5_MAPK7_ST	Q13163	MAP2K5	Q13164	MAPK7	S149	K154R	154	Missense	distal	5	no	106.873	105.339	EPSD;PhosphoSitePlus	GDSC	81.800	Down-regulation
CMGC_MAPK_ERK5_MAPK7_ST	Q06413	MEF2C	Q13164	MAPK7	S98	D102E	102	Missense	distal	4	no	96.927	92.737	EPSD	GDSC	81.800	Down-regulation
CMGC_MAPK_ERK5_MAPK7_ST	Q06413	MEF2C	Q13164	MAPK7	S419	P420S	420	Missense	proximal	1	no	111.494	83.396	EPSD	GDSC;CCLE	81.800	Down-regulation
CMGC_MAPK_ERK5_MAPK7_ST	P29590	PML	Q13164	MAPK7	S527	P526T	526	Missense	proximal	-1	no	92.006	92.221	EPSD	GDSC;CCLE	81.800	Up-regulation
CMGC_MAPK_ERK5_MAPK7_ST	P29590	PML	Q13164	MAPK7	S527	V532I	532	Missense	distal	5	no	92.006	94.110	EPSD	GDSC;CCLE	81.800	Up-regulation
CMGC_MAPK_ERK5_MAPK7_ST	P29590	PML	Q13164	MAPK7	S530	P526T	526	Missense	distal	-4	no	93.594	93.337	EPSD	GDSC;CCLE	81.800	Down-regulation
CMGC_MAPK_ERK5_MAPK7_ST	P29590	PML	Q13164	MAPK7	S530	V532I	532	Missense	proximal	2	no	93.594	99.684	EPSD	GDSC;CCLE	81.800	Up-regulation
CMGC_MAPK_ERK5_MAPK7_ST	P29590	PML	Q13164	MAPK7	S542	N543S	543	Missense	proximal	1	no	83.652	66.273	EPSD	GDSC;CCLE	81.800	Loss
CMGC_MAPK_ERK5_MAPK7_ST	P29590	PML	Q13164	MAPK7	S542	V545M	545	Missense	distal	3	no	83.652	83.466	EPSD	GDSC;CCLE	81.800	Down-regulation
CMGC_MAPK_ERK5_MAPK7_ST	P29590	PML	Q13164	MAPK7	S578	R573*	573	Missense	distal	-5	no	96.073	98.347	EPSD	GDSC	81.800	Up-regulation
CMGC_MAPK_ERK5_MAPK7_ST	P29590	PML	Q13164	MAPK7	S579	R573*	573	Missense	distal	-6	no	86.463	84.113	EPSD	GDSC	81.800	Down-regulation
CMGC_MAPK_ERK5_MAPK7_ST	P29590	PML	Q13164	MAPK7	S580	R573*	573	Missense	distal	-7	no	87.629	87.352	EPSD	GDSC	81.800	Down-regulation
CMGC_DYRK_HIPK_HIPK2_ST	Q9P1Z0	ZBTB4	Q9H2X6	HIPK2	S104	S102A	102	Missense	proximal	-2	no	103.114	102.971	EPSD	GDSC	98.777	Down-regulation
CMGC_DYRK_HIPK_HIPK2_ST	Q9P1Z0	ZBTB4	Q9H2X6	HIPK2	T710	E708K	708	Missense	proximal	-2	no	114.402	114.480	EPSD	GDSC;CCLE	98.777	Up-regulation
CMGC_DYRK_HIPK_HIPK2_ST	P57682	KLF3	Q9H2X6	HIPK2	T49	G56R	56	Missense	distal	7	no	117.825	117.647	EPSD	GDSC;CCLE	98.777	Down-regulation
CMGC_DYRK_HIPK_HIPK2_ST	P57682	KLF3	Q9H2X6	HIPK2	S101	P102S	102	Missense	proximal	1	no	121.389	104.108	EPSD;PhosphoSitePlus	GDSC;CCLE	98.777	Down-regulation
CMGC_DYRK_HIPK_HIPK2_ST	P57682	KLF3	Q9H2X6	HIPK2	S108	P102S	102	Missense	distal	-6	no	116.929	116.935	EPSD;PhosphoSitePlus	GDSC;CCLE	98.777	Up-regulation
CMGC_DYRK_HIPK_HIPK2_ST	P57682	KLF3	Q9H2X6	HIPK2	S224	Q227*	227	Missense	distal	3	no	114.033	113.076	EPSD;PhosphoSitePlus	GDSC	98.777	Down-regulation
CMGC_DYRK_HIPK_HIPK2_ST	P57682	KLF3	Q9H2X6	HIPK2	S250	S250A	250	Missense	central	0	yes	119.124	0.000	EPSD;PhosphoSitePlus	GDSC	98.777	Loss
CMGC_DYRK_HIPK_HIPK2_ST	P57682	KLF3	Q9H2X6	HIPK2	S250	S250F	250	Missense	central	0	yes	119.124	0.000	EPSD;PhosphoSitePlus	GDSC	98.777	Loss
CMGC_DYRK_HIPK_HIPK2_ST	Q04724	TLE1	Q9H2X6	HIPK2	S258	A262T	262	Missense	distal	4	no	101.653	100.897	EPSD	GDSC	98.777	Down-regulation
CMGC_DYRK_HIPK_HIPK2_ST	Q04724	TLE1	Q9H2X6	HIPK2	S258	R261*	261	Missense	distal	3	no	101.653	101.340	EPSD	GDSC	98.777	Down-regulation
CMGC_DYRK_HIPK_HIPK2_ST	Q04724	TLE1	Q9H2X6	HIPK2	S259	A262T	262	Missense	distal	3	no	103.835	103.808	EPSD	GDSC	98.777	Down-regulation
CMGC_DYRK_HIPK_HIPK2_ST	Q04724	TLE1	Q9H2X6	HIPK2	S259	R261*	261	Missense	proximal	2	no	103.835	105.376	EPSD	GDSC	98.777	Up-regulation
CMGC_DYRK_HIPK_HIPK2_ST	Q04724	TLE1	Q9H2X6	HIPK2	S263	A262T	262	Missense	proximal	-1	no	107.281	106.558	EPSD	GDSC	98.777	Down-regulation
CMGC_DYRK_HIPK_HIPK2_ST	Q04724	TLE1	Q9H2X6	HIPK2	S263	R261*	261	Missense	proximal	-2	no	107.281	107.298	EPSD	GDSC	98.777	Up-regulation
CMGC_DYRK_HIPK_HIPK2_ST	Q04724	TLE1	Q9H2X6	HIPK2	S267	A262T	262	Missense	distal	-5	no	102.743	103.316	EPSD	GDSC	98.777	Up-regulation
CMGC_DYRK_HIPK_HIPK2_ST	Q04724	TLE1	Q9H2X6	HIPK2	S267	R261*	261	Missense	distal	-6	no	102.743	102.663	EPSD	GDSC	98.777	Down-regulation
CMGC_DYRK_HIPK_HIPK2_ST	Q04724	TLE1	Q9H2X6	HIPK2	T319	T321M	321	Missense	proximal	2	no	111.778	111.279	EPSD	GDSC;CCLE	98.777	Down-regulation
CMGC_DYRK_HIPK_HIPK2_ST	Q04724	TLE1	Q9H2X6	HIPK2	T321	T321M	321	Missense	central	0	yes	112.012	0.000	EPSD	GDSC;CCLE	98.777	Loss
CMGC_DYRK_HIPK_HIPK2_ST	Q04724	TLE1	Q9H2X6	HIPK2	T328	T321M	321	Missense	distal	-7	no	118.841	118.654	EPSD	GDSC;CCLE	98.777	Down-regulation
CMGC_DYRK_HIPK_HIPK2_ST	Q04724	TLE1	Q9H2X6	HIPK2	S416	D422H	422	Missense	distal	6	no	106.834	106.247	EPSD	GDSC;CCLE	98.777	Down-regulation
CMGC_DYRK_HIPK_HIPK2_ST	P17096	HMGA1	Q9H2X6	HIPK2	T72	A70D	70	Missense	proximal	-2	no	106.663	106.475	EPSD	GDSC;CCLE	98.777	Down-regulation
CMGC_DYRK_HIPK_HIPK2_ST	P46531	NOTCH1	Q9H2X6	HIPK2	S2136	P2133S	2133	Missense	distal	-3	no	104.087	103.906	EPSD	GDSC	98.777	Down-regulation
CMGC_DYRK_HIPK_HIPK2_ST	P46531	NOTCH1	Q9H2X6	HIPK2	S2221	P2216L	2216	Missense	distal	-5	no	105.935	98.512	EPSD	GDSC;CCLE	98.777	Loss
CMGC_DYRK_HIPK_HIPK2_ST	P46531	NOTCH1	Q9H2X6	HIPK2	S2523	S2523*	2523	Missense	central	0	yes	102.633	0.000	EPSD	GDSC	98.777	Loss
CMGC_DYRK_HIPK_HIPK2_ST	P46531	NOTCH1	Q9H2X6	HIPK2	S2524	S2523*	2523	Missense	proximal	-1	no	104.924	103.369	EPSD	GDSC	98.777	Down-regulation
CMGC_DYRK_HIPK_HIPK2_ST	P29590	PML	Q9H2X6	HIPK2	S530	P526T	526	Missense	distal	-4	no	109.869	109.738	EPSD	GDSC;CCLE	98.777	Down-regulation
CMGC_DYRK_HIPK_HIPK2_ST	P29590	PML	Q9H2X6	HIPK2	S530	V532I	532	Missense	proximal	2	no	109.869	110.119	EPSD	GDSC;CCLE	98.777	Up-regulation
CMGC_DYRK_HIPK_HIPK2_ST	P29590	PML	Q9H2X6	HIPK2	S560	A567V	567	Missense	distal	7	no	104.125	103.797	EPSD	GDSC	98.777	Down-regulation
CMGC_DYRK_HIPK_HIPK2_ST	P29590	PML	Q9H2X6	HIPK2	S561	A567V	567	Missense	distal	6	no	104.036	103.669	EPSD	GDSC	98.777	Down-regulation
CMGC_DYRK_HIPK_HIPK2_ST	P51608	MECP2	Q9H2X6	HIPK2	S401	P405A	405	Missense	distal	4	no	105.338	105.471	EPSD	GDSC	98.777	Up-regulation
CMGC_DYRK_HIPK_HIPK2_ST	P51608	MECP2	Q9H2X6	HIPK2	S410	P405A	405	Missense	distal	-5	no	101.580	92.736	EPSD	GDSC	98.777	Loss
CMGC_DYRK_HIPK_HIPK2_ST	P04637	TP53	Q9H2X6	HIPK2	S33	Q38*	38	Missense	distal	5	no	103.633	103.843	EPSD	GDSC	98.777	Up-regulation
CMGC_DYRK_HIPK_HIPK2_ST	P04637	TP53	Q9H2X6	HIPK2	T150	Q144*	144	Missense	distal	-6	no	104.776	104.332	EPSD	GDSC	98.777	Down-regulation
CMGC_DYRK_HIPK_HIPK2_ST	P04637	TP53	Q9H2X6	HIPK2	T150	W146*	146	Missense	distal	-4	no	104.776	105.221	EPSD	GDSC	98.777	Up-regulation
CMGC_DYRK_HIPK_HIPK2_ST	P04637	TP53	Q9H2X6	HIPK2	S314	Q317*	317	Missense	distal	3	no	99.315	98.358	EPSD	GDSC	98.777	Loss
CMGC_DYRK_HIPK_HIPK2_ST	P04637	TP53	Q9H2X6	HIPK2	S314	K319*	319	Missense	distal	5	no	99.315	99.438	EPSD	GDSC	98.777	Up-regulation
CMGC_DYRK_HIPK_HIPK2_ST	P04637	TP53	Q9H2X6	HIPK2	S315	Q317*	317	Missense	proximal	2	no	106.507	105.788	EPSD	GDSC	98.777	Down-regulation
CMGC_DYRK_HIPK_HIPK2_ST	P04637	TP53	Q9H2X6	HIPK2	S315	K319*	319	Missense	distal	4	no	106.507	102.552	EPSD	GDSC	98.777	Down-regulation
CMGC_DYRK_HIPK_HIPK2_ST	P04637	TP53	Q9H2X6	HIPK2	S362	G360V	360	Missense	proximal	-2	no	100.771	100.243	EPSD	GDSC;CCLE	98.777	Down-regulation
CMGC_DYRK_HIPK_HIPK2_ST	O15297	PPM1D	Q9H2X6	HIPK2	T517	T517I	517	Missense	central	0	yes	102.327	0.000	EPSD	GDSC	98.777	Loss
CMGC_DYRK_HIPK_HIPK2_ST	O15297	PPM1D	Q9H2X6	HIPK2	T529	T532A	532	Missense	distal	3	no	112.788	112.815	EPSD	GDSC;CCLE	98.777	Up-regulation
CMGC_DYRK_HIPK_HIPK2_ST	O15297	PPM1D	Q9H2X6	HIPK2	S559	R557L	557	Missense	proximal	-2	no	104.541	104.534	EPSD	GDSC;CCLE	98.777	Down-regulation
CMGC_DYRK_HIPK_HIPK2_ST	Q96EB6	SIRT1	Q9H2X6	HIPK2	T177	T177I	177	Missense	central	0	yes	98.856	0.000	EPSD	GDSC;CCLE	98.777	Loss
CMGC_DYRK_HIPK_HIPK2_ST	Q96EB6	SIRT1	Q9H2X6	HIPK2	S525	E520*	520	Missense	distal	-5	no	98.949	90.853	EPSD	GDSC	98.777	Loss
CMGC_DYRK_HIPK_HIPK2_ST	Q9H2X6	HIPK2	Q9H2X6	HIPK2	S804	K805R	805	Missense	proximal	1	no	89.060	99.416	EPSD	GDSC;CCLE	98.777	Gain
CMGC_DYRK_HIPK_HIPK2_ST	Q9H2X6	HIPK2	Q9H2X6	HIPK2	T838	R833C	833	Missense	distal	-5	no	99.480	85.830	EPSD	GDSC;CCLE	98.777	Loss
CMGC_DYRK_HIPK_HIPK2_ST	Q9H2X6	HIPK2	Q9H2X6	HIPK2	T880	I875V	875	Missense	distal	-5	no	121.162	117.920	PhosphoSitePlus;EPSD	GDSC;CCLE	98.777	Down-regulation
CMGC_DYRK_HIPK_HIPK2_ST	Q9H2X6	HIPK2	Q9H2X6	HIPK2	S882	I875V	875	Missense	distal	-7	no	118.885	118.991	EPSD;PhosphoSitePlus	GDSC;CCLE	98.777	Up-regulation
CMGC_DYRK_HIPK_HIPK2_ST	Q9H2X6	HIPK2	Q9H2X6	HIPK2	S1018	T1022N	1022	Missense	distal	4	no	103.681	102.752	EPSD	GDSC;CCLE	98.777	Down-regulation
CMGC_DYRK_HIPK_HIPK2_ST	P46527	CDKN1B	Q9H2X6	HIPK2	S112	I119V	119	Missense	distal	7	no	103.876	103.730	EPSD	GDSC;CCLE	98.777	Down-regulation
CMGC_DYRK_HIPK_HIPK2_ST	P46527	CDKN1B	Q9H2X6	HIPK2	T142	E146Q	146	Missense	distal	4	no	108.563	109.465	EPSD	GDSC;CCLE	98.777	Up-regulation
CMGC_DYRK_HIPK_HIPK2_ST	P46527	CDKN1B	Q9H2X6	HIPK2	T142	P137L	137	Missense	distal	-5	no	108.563	101.139	EPSD	GDSC;CCLE	98.777	Down-regulation
CMGC_DYRK_HIPK_HIPK2_ST	P46527	CDKN1B	Q9H2X6	HIPK2	S178	G177S	177	Missense	proximal	-1	no	99.666	100.297	EPSD	GDSC;CCLE	98.777	Up-regulation
CMGC_DYRK_HIPK_HIPK2_ST	O00257	CBX4	Q9H2X6	HIPK2	S291	R290P	290	Missense	proximal	-1	no	111.295	112.506	EPSD	GDSC	98.777	Up-regulation
CMGC_DYRK_HIPK_HIPK2_ST	O00257	CBX4	Q9H2X6	HIPK2	S291	E288G	288	Missense	distal	-3	no	111.295	111.458	EPSD	GDSC	98.777	Up-regulation
CMGC_DYRK_HIPK_HIPK2_ST	O00257	CBX4	Q9H2X6	HIPK2	S345	S345F	345	Missense	central	0	yes	104.813	0.000	EPSD	GDSC;CCLE	98.777	Loss
CMGC_DYRK_HIPK_HIPK2_ST	O00257	CBX4	Q9H2X6	HIPK2	S349	S345F	345	Missense	distal	-4	no	110.746	110.552	EPSD	GDSC;CCLE	98.777	Down-regulation
CMGC_DYRK_HIPK_HIPK2_ST	O00257	CBX4	Q9H2X6	HIPK2	T497	S490F	490	Missense	distal	-7	no	120.888	118.946	PhosphoSitePlus	GDSC;CCLE	98.777	Down-regulation
CMGC_DYRK_HIPK_HIPK2_ST	Q9H3D4	TP63	Q9H2X6	HIPK2	S160	T155I	155	Missense	distal	-5	no	104.093	109.309	EPSD	GDSC;CCLE	98.777	Up-regulation
CMGC_DYRK_HIPK_HIPK2_ST	Q9H3D4	TP63	Q9H2X6	HIPK2	S162	T155I	155	Missense	distal	-7	no	117.768	118.181	EPSD	GDSC;CCLE	98.777	Up-regulation
CMGC_DYRK_HIPK_HIPK2_ST	Q9H3D4	TP63	Q9H2X6	HIPK2	S455	S457P	457	Missense	proximal	2	no	108.088	108.123	EPSD	GDSC	98.777	Up-regulation
CMGC_DYRK_HIPK_HIPK2_ST	Q9H3D4	TP63	Q9H2X6	HIPK2	S463	S457P	457	Missense	distal	-6	no	109.982	109.976	EPSD	GDSC	98.777	Down-regulation
CMGC_DYRK_HIPK_HIPK2_ST	Q9H3D4	TP63	Q9H2X6	HIPK2	T491	Q485R	485	Missense	distal	-6	no	114.097	113.733	PhosphoSitePlus	GDSC;CCLE	98.777	Down-regulation
Atypical_PIKK_FRAP_MTOR_ST	Q8N122	RPTOR	P42345	MTOR	S696	L694F	694	Missense	proximal	-2	no	11.129	11.442	EPSD	GDSC;CCLE	6.822	Up-regulation
Atypical_PIKK_FRAP_MTOR_ST	Q8N122	RPTOR	P42345	MTOR	S795	S798P	798	Missense	distal	3	no	8.024	8.010	EPSD	GDSC	6.822	Down-regulation
Atypical_PIKK_FRAP_MTOR_ST	Q8N122	RPTOR	P42345	MTOR	S877	S881P	881	Missense	distal	4	no	10.049	9.793	EPSD	GDSC;CCLE	6.822	Down-regulation
Atypical_PIKK_FRAP_MTOR_ST	Q8N122	RPTOR	P42345	MTOR	S882	S881P	881	Missense	proximal	-1	no	7.315	7.247	EPSD	GDSC;CCLE	6.822	Down-regulation
Atypical_PIKK_FRAP_MTOR_ST	Q13541	EIF4EBP1	P42345	MTOR	S65	P66T	66	Missense	proximal	1	no	9.149	2.877	PhosphoSitePlus;EPSD	GDSC	6.822	Loss
Atypical_PIKK_FRAP_MTOR_ST	Q13541	EIF4EBP1	P42345	MTOR	T70	P66T	66	Missense	distal	-4	no	9.629	9.256	EPSD;PhosphoSitePlus	GDSC	6.822	Down-regulation
Atypical_PIKK_FRAP_MTOR_ST	Q13541	EIF4EBP1	P42345	MTOR	S101	G108S	108	Missense	distal	7	no	15.851	15.466	EPSD	GDSC;CCLE	6.822	Down-regulation
Atypical_PIKK_FRAP_MTOR_ST	P00441	SOD1	P42345	MTOR	S135	A141S	141	Missense	distal	6	no	9.177	9.827	EPSD	GDSC;CCLE	6.822	Up-regulation
Atypical_PIKK_FRAP_MTOR_ST	P00441	SOD1	P42345	MTOR	S143	I150V	150	Missense	distal	7	no	9.269	9.408	EPSD	GDSC;CCLE	6.822	Up-regulation
Atypical_PIKK_FRAP_MTOR_ST	P00441	SOD1	P42345	MTOR	S143	I150T	150	Missense	distal	7	no	9.269	7.949	EPSD	GDSC;CCLE	6.822	Down-regulation
Atypical_PIKK_FRAP_MTOR_ST	P00441	SOD1	P42345	MTOR	S143	A141S	141	Missense	proximal	-2	no	9.269	8.708	EPSD	GDSC;CCLE	6.822	Down-regulation
Atypical_PIKK_FRAP_MTOR_ST	O75179	ANKRD17	P42345	MTOR	T913	P914H	914	Missense	proximal	1	no	10.254	-16.937	EPSD	GDSC;CCLE	6.822	Loss
Atypical_PIKK_FRAP_MTOR_ST	O75179	ANKRD17	P42345	MTOR	T913	H908R	908	Missense	distal	-5	no	10.254	10.249	EPSD	GDSC;CCLE	6.822	Down-regulation
Atypical_PIKK_FRAP_MTOR_ST	O75179	ANKRD17	P42345	MTOR	T913	H908N	908	Missense	distal	-5	no	10.254	10.018	EPSD	GDSC;CCLE	6.822	Down-regulation
Atypical_PIKK_FRAP_MTOR_ST	O75179	ANKRD17	P42345	MTOR	S1220	S1215N	1215	Missense	distal	-5	no	10.849	10.760	EPSD	GDSC;CCLE	6.822	Down-regulation
Atypical_PIKK_FRAP_MTOR_ST	O75179	ANKRD17	P42345	MTOR	S1319	I1326L	1326	Missense	distal	7	no	6.584	7.186	EPSD	GDSC;CCLE	6.822	Gain
Atypical_PIKK_FRAP_MTOR_ST	O75179	ANKRD17	P42345	MTOR	S1607	E1602K	1602	Missense	distal	-5	no	7.673	7.965	EPSD	GDSC;CCLE	6.822	Up-regulation
Atypical_PIKK_FRAP_MTOR_ST	O75179	ANKRD17	P42345	MTOR	S1672	K1670M	1670	Missense	proximal	-2	no	7.344	6.691	EPSD	GDSC	6.822	Loss
Atypical_PIKK_FRAP_MTOR_ST	O75179	ANKRD17	P42345	MTOR	S1709	P1710S	1710	Missense	proximal	1	no	12.485	3.961	EPSD	GDSC;CCLE	6.822	Loss
Atypical_PIKK_FRAP_MTOR_ST	O75179	ANKRD17	P42345	MTOR	T2279	S2278P	2278	Missense	proximal	-1	no	12.302	12.234	EPSD	GDSC;CCLE	6.822	Down-regulation
Atypical_PIKK_FRAP_MTOR_ST	O75179	ANKRD17	P42345	MTOR	S2448	V2445I	2445	Missense	distal	-3	no	10.470	10.769	EPSD	GDSC;CCLE	6.822	Up-regulation
Atypical_PIKK_FRAP_MTOR_ST	O75179	ANKRD17	P42345	MTOR	T2509	R2502*	2502	Missense	distal	-7	no	9.021	9.065	EPSD	GDSC	6.822	Up-regulation
Atypical_PIKK_FRAP_MTOR_ST	Q9HB90	RRAGC	P42345	MTOR	S382	S376R	376	Missense	distal	-6	no	7.160	7.268	EPSD	GDSC	6.822	Up-regulation
Atypical_PIKK_FRAP_MTOR_ST	Q9HB90	RRAGC	P42345	MTOR	S382	A388V	388	Missense	distal	6	no	7.160	7.852	EPSD	GDSC;CCLE	6.822	Up-regulation
Atypical_PIKK_FRAP_MTOR_ST	Q9HB90	RRAGC	P42345	MTOR	T394	A388V	388	Missense	distal	-6	no	8.997	8.713	EPSD;PhosphoSitePlus	GDSC;CCLE	6.822	Down-regulation
Atypical_PIKK_FRAP_MTOR_ST	O00418	EEF2K	P42345	MTOR	S71	Y69H	69	Missense	proximal	-2	no	8.697	8.882	EPSD	GDSC;CCLE	6.822	Up-regulation
Atypical_PIKK_FRAP_MTOR_ST	O00418	EEF2K	P42345	MTOR	S72	Y69H	69	Missense	distal	-3	no	9.703	9.063	PhosphoSitePlus;EPSD	GDSC;CCLE	6.822	Down-regulation
Atypical_PIKK_FRAP_MTOR_ST	O00418	EEF2K	P42345	MTOR	S74	Y69H	69	Missense	distal	-5	no	12.409	12.062	EPSD;PhosphoSitePlus	GDSC;CCLE	6.822	Down-regulation
Atypical_PIKK_FRAP_MTOR_ST	O00418	EEF2K	P42345	MTOR	S627	G623S	623	Missense	distal	-4	no	10.759	11.326	EPSD	GDSC	6.822	Up-regulation
Atypical_PIKK_FRAP_MTOR_ST	Q9UQ35	SRRM2	P42345	MTOR	T111	A117V	117	Missense	distal	6	no	7.502	8.194	EPSD	GDSC	6.822	Up-regulation
Atypical_PIKK_FRAP_MTOR_ST	Q9UQ35	SRRM2	P42345	MTOR	S295	R294Q	294	Missense	proximal	-1	no	11.978	11.997	EPSD	GDSC;CCLE	6.822	Up-regulation
Atypical_PIKK_FRAP_MTOR_ST	Q9UQ35	SRRM2	P42345	MTOR	S297	R294Q	294	Missense	distal	-3	no	9.264	8.656	EPSD	GDSC;CCLE	6.822	Down-regulation
Atypical_PIKK_FRAP_MTOR_ST	Q9UQ35	SRRM2	P42345	MTOR	S353	G360C	360	Missense	distal	7	no	10.140	10.978	EPSD	GDSC;CCLE	6.822	Up-regulation
Atypical_PIKK_FRAP_MTOR_ST	Q9UQ35	SRRM2	P42345	MTOR	T367	G360C	360	Missense	distal	-7	no	9.152	7.861	EPSD	GDSC;CCLE	6.822	Down-regulation
Atypical_PIKK_FRAP_MTOR_ST	Q9UQ35	SRRM2	P42345	MTOR	S398	R403P	403	Missense	distal	5	no	8.860	7.981	EPSD	GDSC;CCLE	6.822	Down-regulation
Atypical_PIKK_FRAP_MTOR_ST	Q9UQ35	SRRM2	P42345	MTOR	T476	S478A	478	Missense	proximal	2	no	8.522	7.758	EPSD	GDSC;CCLE	6.822	Down-regulation
Atypical_PIKK_FRAP_MTOR_ST	Q9UQ35	SRRM2	P42345	MTOR	S510	Q512P	512	Missense	proximal	2	no	5.136	7.355	EPSD	GDSC;CCLE	6.822	Gain
Atypical_PIKK_FRAP_MTOR_ST	Q9UQ35	SRRM2	P42345	MTOR	S534	P537S	537	Missense	distal	3	no	7.694	7.709	EPSD	GDSC	6.822	Up-regulation
Atypical_PIKK_FRAP_MTOR_ST	Q9UQ35	SRRM2	P42345	MTOR	S543	P537S	537	Missense	distal	-6	no	6.935	6.914	EPSD	GDSC	6.822	Down-regulation
Atypical_PIKK_FRAP_MTOR_ST	Q9UQ35	SRRM2	P42345	MTOR	S566	S562T	562	Missense	distal	-4	no	11.868	11.367	EPSD	GDSC;CCLE	6.822	Down-regulation
Atypical_PIKK_FRAP_MTOR_ST	Q9UQ35	SRRM2	P42345	MTOR	S647	R648C	648	Missense	proximal	1	no	5.693	7.132	EPSD	GDSC;CCLE	6.822	Gain
Atypical_PIKK_FRAP_MTOR_ST	Q9UQ35	SRRM2	P42345	MTOR	T673	R670L	670	Missense	distal	-3	no	6.771	6.841	EPSD	GDSC;CCLE	6.822	Gain
Atypical_PIKK_FRAP_MTOR_ST	Q9UQ35	SRRM2	P42345	MTOR	S706	R705S	705	Missense	proximal	-1	no	8.051	8.213	EPSD	GDSC	6.822	Up-regulation
Atypical_PIKK_FRAP_MTOR_ST	Q9UQ35	SRRM2	P42345	MTOR	T792	P794L	794	Missense	proximal	2	no	8.079	7.389	EPSD	GDSC;CCLE	6.822	Down-regulation
Atypical_PIKK_FRAP_MTOR_ST	Q9UQ35	SRRM2	P42345	MTOR	S908	P915S	915	Missense	distal	7	no	8.321	8.300	EPSD	GDSC;CCLE	6.822	Down-regulation
Atypical_PIKK_FRAP_MTOR_ST	Q9UQ35	SRRM2	P42345	MTOR	S935	P938S	938	Missense	distal	3	no	11.289	11.303	EPSD	GDSC	6.822	Up-regulation
Atypical_PIKK_FRAP_MTOR_ST	Q9UQ35	SRRM2	P42345	MTOR	S935	P938L	938	Missense	distal	3	no	11.289	9.034	EPSD	GDSC	6.822	Down-regulation
Atypical_PIKK_FRAP_MTOR_ST	Q9UQ35	SRRM2	P42345	MTOR	S937	P938S	938	Missense	proximal	1	no	9.099	0.575	EPSD	GDSC	6.822	Loss
Atypical_PIKK_FRAP_MTOR_ST	Q9UQ35	SRRM2	P42345	MTOR	S937	P938L	938	Missense	proximal	1	no	9.099	3.129	EPSD	GDSC	6.822	Loss
Atypical_PIKK_FRAP_MTOR_ST	Q9UQ35	SRRM2	P42345	MTOR	S937	S943L	943	Missense	distal	6	no	9.099	7.909	EPSD	GDSC;CCLE	6.822	Down-regulation
Atypical_PIKK_FRAP_MTOR_ST	Q9UQ35	SRRM2	P42345	MTOR	S974	Y967H	967	Missense	distal	-7	no	14.879	13.859	EPSD	GDSC;CCLE	6.822	Down-regulation
Atypical_PIKK_FRAP_MTOR_ST	Q9UQ35	SRRM2	P42345	MTOR	S1073	R1077K	1077	Missense	distal	4	no	9.445	9.747	EPSD	GDSC;CCLE	6.822	Up-regulation
Atypical_PIKK_FRAP_MTOR_ST	Q9UQ35	SRRM2	P42345	MTOR	S1093	Q1087*	1087	Missense	distal	-6	no	10.087	9.362	EPSD	GDSC	6.822	Down-regulation
Atypical_PIKK_FRAP_MTOR_ST	Q9UQ35	SRRM2	P42345	MTOR	S1093	S1099F	1099	Missense	distal	6	no	10.087	9.512	EPSD	GDSC;CCLE	6.822	Down-regulation
Atypical_PIKK_FRAP_MTOR_ST	Q9UQ35	SRRM2	P42345	MTOR	S1103	S1099F	1099	Missense	distal	-4	no	8.453	8.477	EPSD	GDSC;CCLE	6.822	Up-regulation
Atypical_PIKK_FRAP_MTOR_ST	Q9UQ35	SRRM2	P42345	MTOR	S1132	P1133S	1133	Missense	proximal	1	no	11.262	2.738	EPSD	GDSC;CCLE	6.822	Loss
Atypical_PIKK_FRAP_MTOR_ST	Q9UQ35	SRRM2	P42345	MTOR	S1144	S1150W	1150	Missense	distal	6	no	9.835	8.544	EPSD	GDSC;CCLE	6.822	Down-regulation
Atypical_PIKK_FRAP_MTOR_ST	Q9UQ35	SRRM2	P42345	MTOR	S1157	S1150W	1150	Missense	distal	-7	no	8.247	7.949	EPSD	GDSC;CCLE	6.822	Down-regulation
Atypical_PIKK_FRAP_MTOR_ST	Q9UQ35	SRRM2	P42345	MTOR	S1179	D1185H	1185	Missense	distal	6	no	7.467	6.244	EPSD	GDSC	6.822	Loss
Atypical_PIKK_FRAP_MTOR_ST	Q9UQ35	SRRM2	P42345	MTOR	S1179	A1176G	1176	Missense	distal	-3	no	7.467	8.333	EPSD	GDSC	6.822	Up-regulation
Atypical_PIKK_FRAP_MTOR_ST	Q9UQ35	SRRM2	P42345	MTOR	S1219	G1217V	1217	Missense	proximal	-2	no	7.728	7.080	EPSD	GDSC;CCLE	6.822	Down-regulation
Atypical_PIKK_FRAP_MTOR_ST	Q9UQ35	SRRM2	P42345	MTOR	S1264	T1265I	1265	Missense	proximal	1	no	6.085	7.298	EPSD	GDSC;CCLE	6.822	Gain
Atypical_PIKK_FRAP_MTOR_ST	Q9UQ35	SRRM2	P42345	MTOR	S1271	P1278R	1278	Missense	distal	7	no	6.669	7.441	EPSD	GDSC;CCLE	6.822	Gain
Atypical_PIKK_FRAP_MTOR_ST	Q9UQ35	SRRM2	P42345	MTOR	S1271	E1276Q	1276	Missense	distal	5	no	6.669	7.238	EPSD	GDSC;CCLE	6.822	Gain
Atypical_PIKK_FRAP_MTOR_ST	Q9UQ35	SRRM2	P42345	MTOR	S1311	E1313Q	1313	Missense	proximal	2	no	8.166	5.603	EPSD	GDSC;CCLE	6.822	Loss
Atypical_PIKK_FRAP_MTOR_ST	Q9UQ35	SRRM2	P42345	MTOR	S1318	E1313Q	1313	Missense	distal	-5	no	7.678	8.041	EPSD;PhosphoSitePlus	GDSC;CCLE	6.822	Up-regulation
Atypical_PIKK_FRAP_MTOR_ST	Q9UQ35	SRRM2	P42345	MTOR	S1320	E1313Q	1313	Missense	distal	-7	no	13.108	12.676	EPSD	GDSC;CCLE	6.822	Down-regulation
Atypical_PIKK_FRAP_MTOR_ST	Q9UQ35	SRRM2	P42345	MTOR	S1424	E1426*	1426	Missense	proximal	2	no	11.400	4.072	EPSD	GDSC	6.822	Loss
Atypical_PIKK_FRAP_MTOR_ST	Q9UQ35	SRRM2	P42345	MTOR	S1444	S1439G	1439	Missense	distal	-5	no	12.094	12.161	EPSD	GDSC;CCLE	6.822	Up-regulation
Atypical_PIKK_FRAP_MTOR_ST	Q9UQ35	SRRM2	P42345	MTOR	S1444	D1449H	1449	Missense	distal	5	no	12.094	13.356	EPSD	GDSC;CCLE	6.822	Up-regulation
Atypical_PIKK_FRAP_MTOR_ST	Q9UQ35	SRRM2	P42345	MTOR	T1453	D1449H	1449	Missense	distal	-4	no	11.406	9.298	EPSD	GDSC;CCLE	6.822	Down-regulation
Atypical_PIKK_FRAP_MTOR_ST	Q9UQ35	SRRM2	P42345	MTOR	S1463	M1466I	1466	Missense	distal	3	no	7.571	7.739	EPSD	GDSC;CCLE	6.822	Up-regulation
Atypical_PIKK_FRAP_MTOR_ST	Q9UQ35	SRRM2	P42345	MTOR	S1463	P1464S	1464	Missense	proximal	1	no	7.571	-0.953	EPSD	GDSC;CCLE	6.822	Loss
Atypical_PIKK_FRAP_MTOR_ST	Q9UQ35	SRRM2	P42345	MTOR	T1472	M1466I	1466	Missense	distal	-6	no	11.668	11.097	EPSD	GDSC;CCLE	6.822	Down-regulation
Atypical_PIKK_FRAP_MTOR_ST	Q9UQ35	SRRM2	P42345	MTOR	S1499	N1506H	1506	Missense	distal	7	no	12.458	12.494	EPSD	GDSC	6.822	Up-regulation
Atypical_PIKK_FRAP_MTOR_ST	Q9UQ35	SRRM2	P42345	MTOR	S1502	N1506H	1506	Missense	distal	4	no	8.077	7.719	EPSD	GDSC	6.822	Down-regulation
Atypical_PIKK_FRAP_MTOR_ST	Q9UQ35	SRRM2	P42345	MTOR	T1511	N1506H	1506	Missense	distal	-5	no	8.008	8.243	EPSD	GDSC	6.822	Up-regulation
Atypical_PIKK_FRAP_MTOR_ST	Q9UQ35	SRRM2	P42345	MTOR	T1531	R1530P	1530	Missense	proximal	-1	no	13.389	13.483	EPSD	GDSC	6.822	Up-regulation
Atypical_PIKK_FRAP_MTOR_ST	Q9UQ35	SRRM2	P42345	MTOR	S1559	D1560N	1560	Missense	proximal	1	no	6.938	8.284	EPSD	GDSC	6.822	Up-regulation
Atypical_PIKK_FRAP_MTOR_ST	Q9UQ35	SRRM2	P42345	MTOR	S1582	D1586A	1586	Missense	distal	4	no	10.483	10.080	EPSD	GDSC;CCLE	6.822	Down-regulation
Atypical_PIKK_FRAP_MTOR_ST	Q9UQ35	SRRM2	P42345	MTOR	S1592	D1586A	1586	Missense	distal	-6	no	8.450	8.008	EPSD	GDSC;CCLE	6.822	Down-regulation
Atypical_PIKK_FRAP_MTOR_ST	Q9UQ35	SRRM2	P42345	MTOR	S1592	R1594W	1594	Missense	proximal	2	no	8.450	9.342	EPSD	GDSC;CCLE	6.822	Up-regulation
Atypical_PIKK_FRAP_MTOR_ST	Q9UQ35	SRRM2	P42345	MTOR	S1648	P1647S	1647	Missense	proximal	-1	no	14.914	14.982	EPSD	GDSC;CCLE	6.822	Up-regulation
Atypical_PIKK_FRAP_MTOR_ST	Q9UQ35	SRRM2	P42345	MTOR	S1648	S1652I	1652	Missense	distal	4	no	14.914	14.478	EPSD	GDSC;CCLE	6.822	Down-regulation
Atypical_PIKK_FRAP_MTOR_ST	Q9UQ35	SRRM2	P42345	MTOR	S1654	P1647S	1647	Missense	distal	-7	no	9.153	9.590	EPSD	GDSC;CCLE	6.822	Up-regulation
Atypical_PIKK_FRAP_MTOR_ST	Q9UQ35	SRRM2	P42345	MTOR	S1654	S1652I	1652	Missense	proximal	-2	no	9.153	8.713	EPSD	GDSC;CCLE	6.822	Down-regulation
Atypical_PIKK_FRAP_MTOR_ST	Q9UQ35	SRRM2	P42345	MTOR	S1658	S1652I	1652	Missense	distal	-6	no	11.333	10.774	EPSD	GDSC;CCLE	6.822	Down-regulation
Atypical_PIKK_FRAP_MTOR_ST	Q9UQ35	SRRM2	P42345	MTOR	S1675	T1680I	1680	Missense	distal	5	no	7.276	8.176	EPSD	GDSC;CCLE	6.822	Up-regulation
Atypical_PIKK_FRAP_MTOR_ST	Q9UQ35	SRRM2	P42345	MTOR	T1684	T1680I	1680	Missense	distal	-4	no	8.317	7.894	EPSD	GDSC;CCLE	6.822	Down-regulation
Atypical_PIKK_FRAP_MTOR_ST	Q9UQ35	SRRM2	P42345	MTOR	S1694	R1692L	1692	Missense	proximal	-2	no	11.187	11.180	EPSD	GDSC;CCLE	6.822	Down-regulation
Atypical_PIKK_FRAP_MTOR_ST	Q9UQ35	SRRM2	P42345	MTOR	S1727	S1729L	1729	Missense	proximal	2	no	10.374	10.179	EPSD	GDSC;CCLE	6.822	Down-regulation
Atypical_PIKK_FRAP_MTOR_ST	Q9UQ35	SRRM2	P42345	MTOR	S1732	S1729L	1729	Missense	distal	-3	no	10.028	10.443	EPSD	GDSC;CCLE	6.822	Up-regulation
Atypical_PIKK_FRAP_MTOR_ST	Q9UQ35	SRRM2	P42345	MTOR	S1762	T1756I	1756	Missense	distal	-6	no	10.436	9.935	EPSD	GDSC	6.822	Down-regulation
Atypical_PIKK_FRAP_MTOR_ST	Q9UQ35	SRRM2	P42345	MTOR	T1844	S1842C	1842	Missense	proximal	-2	no	10.177	10.327	EPSD	GDSC;CCLE	6.822	Up-regulation
Atypical_PIKK_FRAP_MTOR_ST	Q9UQ35	SRRM2	P42345	MTOR	S1869	R1867G	1867	Missense	proximal	-2	no	6.552	7.409	EPSD	GDSC	6.822	Gain
Atypical_PIKK_FRAP_MTOR_ST	Q9UQ35	SRRM2	P42345	MTOR	T1939	R1944C	1944	Missense	distal	5	no	10.018	9.803	EPSD	GDSC;CCLE	6.822	Down-regulation
Atypical_PIKK_FRAP_MTOR_ST	Q9UQ35	SRRM2	P42345	MTOR	T1950	R1944C	1944	Missense	distal	-6	no	11.438	11.565	EPSD	GDSC;CCLE	6.822	Up-regulation
Atypical_PIKK_FRAP_MTOR_ST	Q9UQ35	SRRM2	P42345	MTOR	T2034	R2039H	2039	Missense	distal	5	no	8.206	8.511	EPSD	GDSC	6.822	Up-regulation
Atypical_PIKK_FRAP_MTOR_ST	Q9UQ35	SRRM2	P42345	MTOR	S2046	R2052P	2052	Missense	distal	6	no	10.758	12.550	EPSD	GDSC	6.822	Up-regulation
Atypical_PIKK_FRAP_MTOR_ST	Q9UQ35	SRRM2	P42345	MTOR	S2046	R2052C	2052	Missense	distal	6	no	10.758	10.885	EPSD	GDSC	6.822	Up-regulation
Atypical_PIKK_FRAP_MTOR_ST	Q9UQ35	SRRM2	P42345	MTOR	S2046	R2039H	2039	Missense	distal	-7	no	10.758	10.409	EPSD	GDSC	6.822	Down-regulation
Atypical_PIKK_FRAP_MTOR_ST	Q9UQ35	SRRM2	P42345	MTOR	T2058	R2052P	2052	Missense	distal	-6	no	11.832	11.745	EPSD	GDSC	6.822	Down-regulation
Atypical_PIKK_FRAP_MTOR_ST	Q9UQ35	SRRM2	P42345	MTOR	T2058	R2052C	2052	Missense	distal	-6	no	11.832	11.959	EPSD	GDSC	6.822	Up-regulation
Atypical_PIKK_FRAP_MTOR_ST	Q9UQ35	SRRM2	P42345	MTOR	T2058	R2057H	2057	Missense	proximal	-1	no	11.832	11.873	EPSD	GDSC;CCLE	6.822	Up-regulation
Atypical_PIKK_FRAP_MTOR_ST	Q9UQ35	SRRM2	P42345	MTOR	S2123	P2120L	2120	Missense	distal	-3	no	6.050	6.897	EPSD	GDSC;CCLE	6.822	Gain
Atypical_PIKK_FRAP_MTOR_ST	Q9UQ35	SRRM2	P42345	MTOR	T2261	N2255I	2255	Missense	distal	-6	no	7.929	8.056	EPSD	GDSC;CCLE	6.822	Up-regulation
Atypical_PIKK_FRAP_MTOR_ST	Q9UQ35	SRRM2	P42345	MTOR	T2316	T2316I	2316	Missense	central	0	yes	9.459	0.000	EPSD	GDSC;CCLE	6.822	Loss
Atypical_PIKK_FRAP_MTOR_ST	Q9UQ35	SRRM2	P42345	MTOR	T2316	A2321T	2321	Missense	distal	5	no	9.459	8.633	EPSD	GDSC;CCLE	6.822	Down-regulation
Atypical_PIKK_FRAP_MTOR_ST	Q9UQ35	SRRM2	P42345	MTOR	S2398	S2394R	2394	Missense	distal	-4	no	9.346	9.461	EPSD	GDSC;CCLE	6.822	Up-regulation
Atypical_PIKK_FRAP_MTOR_ST	Q9UQ35	SRRM2	P42345	MTOR	S2449	Q2446H	2446	Missense	distal	-3	no	12.169	12.031	EPSD	GDSC	6.822	Down-regulation
Atypical_PIKK_FRAP_MTOR_ST	Q9UQ35	SRRM2	P42345	MTOR	S2545	S2550L	2550	Missense	distal	5	no	7.702	9.189	EPSD	GDSC;CCLE	6.822	Up-regulation
Atypical_PIKK_FRAP_MTOR_ST	Q9UQ35	SRRM2	P42345	MTOR	S2545	S2551L	2551	Missense	distal	6	no	7.702	6.513	EPSD	GDSC;CCLE	6.822	Loss
Atypical_PIKK_FRAP_MTOR_ST	Q9UQ35	SRRM2	P42345	MTOR	S2650	P2654S	2654	Missense	distal	4	no	10.432	10.688	EPSD	GDSC	6.822	Up-regulation
Atypical_PIKK_FRAP_MTOR_ST	Q9UQ35	SRRM2	P42345	MTOR	S2694	R2699H	2699	Missense	distal	5	no	10.965	11.270	EPSD	GDSC;CCLE	6.822	Up-regulation
Atypical_PIKK_FRAP_MTOR_ST	Q9UQ35	SRRM2	P42345	MTOR	S2702	R2699H	2699	Missense	distal	-3	no	7.488	6.741	EPSD	GDSC;CCLE	6.822	Loss
Atypical_PIKK_FRAP_MTOR_ST	Q9UQ35	SRRM2	P42345	MTOR	S2706	R2699H	2699	Missense	distal	-7	no	7.986	7.636	EPSD	GDSC;CCLE	6.822	Down-regulation
Atypical_PIKK_FRAP_MTOR_ST	P42345	MTOR	P42345	MTOR	S1166	R1161*	1161	Missense	distal	-5	no	8.242	8.461	EPSD	GDSC	6.822	Up-regulation
Atypical_PIKK_FRAP_MTOR_ST	P42345	MTOR	P42345	MTOR	T1948	P1951S	1951	Missense	distal	3	no	10.116	10.130	EPSD	GDSC	6.822	Up-regulation
Atypical_PIKK_FRAP_MTOR_ST	P55199	ELL	P42345	MTOR	T368	P369Q	369	Missense	proximal	1	no	10.560	1.946	EPSD	GDSC;CCLE	6.822	Loss
Atypical_PIKK_FRAP_MTOR_ST	O75385	ULK1	P42345	MTOR	S307	T309P	309	Missense	proximal	2	no	7.409	7.963	EPSD	GDSC	6.822	Up-regulation
Atypical_PIKK_FRAP_MTOR_ST	O75385	ULK1	P42345	MTOR	S307	G301S	301	Missense	distal	-6	no	7.409	7.287	EPSD	GDSC;CCLE	6.822	Down-regulation
Atypical_PIKK_FRAP_MTOR_ST	O75385	ULK1	P42345	MTOR	S307	S310P	310	Missense	distal	3	no	7.409	7.395	EPSD	GDSC	6.822	Down-regulation
Atypical_PIKK_FRAP_MTOR_ST	O75385	ULK1	P42345	MTOR	S308	T309P	309	Missense	proximal	1	no	3.369	9.640	EPSD	GDSC	6.822	Gain
Atypical_PIKK_FRAP_MTOR_ST	O75385	ULK1	P42345	MTOR	T309	S310P	310	Missense	proximal	1	no	0.896	9.420	EPSD	GDSC	6.822	Gain
Atypical_PIKK_FRAP_MTOR_ST	O75385	ULK1	P42345	MTOR	S314	T309P	309	Missense	distal	-5	no	10.170	10.211	EPSD	GDSC	6.822	Up-regulation
Atypical_PIKK_FRAP_MTOR_ST	O75385	ULK1	P42345	MTOR	S314	S310P	310	Missense	distal	-4	no	10.170	10.041	EPSD	GDSC	6.822	Down-regulation
Atypical_PIKK_FRAP_MTOR_ST	O75385	ULK1	P42345	MTOR	S330	A332T	332	Missense	proximal	2	no	6.752	7.457	EPSD	GDSC;CCLE	6.822	Gain
Atypical_PIKK_FRAP_MTOR_ST	O75385	ULK1	P42345	MTOR	S411	A418T	418	Missense	distal	7	no	9.285	8.765	EPSD	GDSC	6.822	Down-regulation
Atypical_PIKK_FRAP_MTOR_ST	O75385	ULK1	P42345	MTOR	S413	A418T	418	Missense	distal	5	no	12.999	12.173	EPSD	GDSC	6.822	Down-regulation
Atypical_PIKK_FRAP_MTOR_ST	O75385	ULK1	P42345	MTOR	S544	L550P	550	Missense	distal	6	no	7.935	9.094	EPSD	GDSC	6.822	Up-regulation
Atypical_PIKK_FRAP_MTOR_ST	O75385	ULK1	P42345	MTOR	S583	D576N	576	Missense	distal	-7	no	9.447	9.012	EPSD	GDSC;CCLE	6.822	Down-regulation
Atypical_PIKK_FRAP_MTOR_ST	O75385	ULK1	P42345	MTOR	S623	P624S	624	Missense	proximal	1	no	10.840	2.316	EPSD	GDSC;CCLE	6.822	Loss
Atypical_PIKK_FRAP_MTOR_ST	O75385	ULK1	P42345	MTOR	T636	Q640K	640	Missense	distal	4	no	14.602	14.772	EPSD	GDSC;CCLE	6.822	Up-regulation
Atypical_PIKK_FRAP_MTOR_ST	O75385	ULK1	P42345	MTOR	S638	Q640K	640	Missense	proximal	2	no	7.101	8.759	EPSD;PhosphoSitePlus	GDSC;CCLE	6.822	Up-regulation
Atypical_PIKK_FRAP_MTOR_ST	O75385	ULK1	P42345	MTOR	S758	G762R	762	Missense	distal	4	no	11.865	11.815	PhosphoSitePlus;EPSD	GDSC	6.822	Down-regulation
Atypical_PIKK_FRAP_MTOR_ST	Q8TB45	DEPTOR	P42345	MTOR	S15	A22G	22	Missense	distal	7	no	6.440	7.250	EPSD	GDSC	6.822	Gain
Atypical_PIKK_FRAP_MTOR_ST	Q8TB45	DEPTOR	P42345	MTOR	T149	Q152P	152	Missense	distal	3	no	5.324	6.855	EPSD	GDSC	6.822	Gain
Atypical_PIKK_FRAP_MTOR_ST	Q8TB45	DEPTOR	P42345	MTOR	S235	H242N	242	Missense	distal	7	no	13.932	13.895	EPSD	GDSC	6.822	Down-regulation
Atypical_PIKK_FRAP_MTOR_ST	Q8TB45	DEPTOR	P42345	MTOR	S235	Q239K	239	Missense	distal	4	no	13.932	14.102	EPSD	GDSC;CCLE	6.822	Up-regulation
Atypical_PIKK_FRAP_MTOR_ST	Q8TB45	DEPTOR	P42345	MTOR	S244	H242N	242	Missense	proximal	-2	no	10.341	10.108	EPSD	GDSC	6.822	Down-regulation
Atypical_PIKK_FRAP_MTOR_ST	Q8TB45	DEPTOR	P42345	MTOR	S244	Q239K	239	Missense	distal	-5	no	10.341	10.271	EPSD	GDSC;CCLE	6.822	Down-regulation
Atypical_PIKK_FRAP_MTOR_ST	Q8TB45	DEPTOR	P42345	MTOR	T321	E317*	317	Missense	distal	-4	no	12.533	12.239	EPSD	GDSC	6.822	Down-regulation
Atypical_PIKK_FRAP_MTOR_ST	Q9P2Y5	UVRAG	P42345	MTOR	T518	N524T	524	Missense	distal	6	no	10.015	10.335	EPSD	GDSC;CCLE	6.822	Up-regulation
Atypical_PIKK_FRAP_MTOR_ST	Q9P2Y5	UVRAG	P42345	MTOR	S550	K543N	543	Missense	distal	-7	no	8.645	9.068	EPSD;PhosphoSitePlus	GDSC	6.822	Up-regulation
Atypical_PIKK_FRAP_MTOR_ST	Q9P2Y5	UVRAG	P42345	MTOR	S550	L551F	551	Missense	proximal	1	no	8.645	8.093	EPSD;PhosphoSitePlus	GDSC;CCLE	6.822	Down-regulation
Atypical_PIKK_FRAP_MTOR_ST	Q9P2Y5	UVRAG	P42345	MTOR	S571	V569L	569	Missense	proximal	-2	no	7.978	7.761	EPSD;PhosphoSitePlus	GDSC;CCLE	6.822	Down-regulation
Atypical_PIKK_FRAP_MTOR_ST	Q9P2Y5	UVRAG	P42345	MTOR	S571	A577T	577	Missense	distal	6	no	7.978	7.714	EPSD;PhosphoSitePlus	GDSC;CCLE	6.822	Down-regulation
Atypical_PIKK_FRAP_MTOR_ST	Q9P2Y5	UVRAG	P42345	MTOR	S696	R695S	695	Missense	proximal	-1	no	9.716	9.878	EPSD	GDSC	6.822	Up-regulation
Atypical_PIKK_FRAP_MTOR_ST	P19484	TFEB	P42345	MTOR	S142	A139V	139	Missense	distal	-3	no	11.712	12.341	EPSD	GDSC;CCLE	6.822	Up-regulation
Atypical_PIKK_FRAP_MTOR_ST	P19484	TFEB	P42345	MTOR	S211	G206S	206	Missense	distal	-5	no	8.216	8.148	EPSD;PhosphoSitePlus	GDSC;CCLE	6.822	Down-regulation
Atypical_PIKK_FRAP_MTOR_ST	P19484	TFEB	P42345	MTOR	S211	V207I	207	Missense	distal	-4	no	8.216	7.974	EPSD;PhosphoSitePlus	GDSC	6.822	Down-regulation
Atypical_PIKK_FRAP_MTOR_ST	P19484	TFEB	P42345	MTOR	S423	F425L	425	Missense	proximal	2	no	8.283	9.822	EPSD	GDSC	6.822	Up-regulation
Atypical_PIKK_FRAP_MTOR_ST	P19484	TFEB	P42345	MTOR	S455	S455P	455	Missense	central	0	yes	14.349	0.000	EPSD	GDSC;CCLE	6.822	Loss
Atypical_PIKK_FRAP_MTOR_ST	P19484	TFEB	P42345	MTOR	S462	S455P	455	Missense	distal	-7	no	10.081	9.644	EPSD	GDSC;CCLE	6.822	Down-regulation
Atypical_PIKK_FRAP_MTOR_ST	P19484	TFEB	P42345	MTOR	S462	R465W	465	Missense	distal	3	no	10.081	8.321	EPSD	GDSC;CCLE	6.822	Down-regulation
Atypical_PIKK_FRAP_MTOR_ST	P19484	TFEB	P42345	MTOR	S467	R465W	465	Missense	proximal	-2	no	10.630	10.332	EPSD	GDSC;CCLE	6.822	Down-regulation
Atypical_PIKK_FRAP_MTOR_ST	P19484	TFEB	P42345	MTOR	S469	R465W	465	Missense	distal	-4	no	17.972	18.082	EPSD	GDSC;CCLE	6.822	Up-regulation
Atypical_PIKK_FRAP_MTOR_ST	Q9H4L4	SENP3	P42345	MTOR	S212	P216S	216	Missense	distal	4	no	7.513	7.768	EPSD	GDSC;CCLE	6.822	Up-regulation
Atypical_PIKK_FRAP_MTOR_ST	Q9H4L4	SENP3	P42345	MTOR	T229	D224Y	224	Missense	distal	-5	no	9.516	10.054	EPSD	GDSC	6.822	Up-regulation
Atypical_PIKK_FRAP_MTOR_ST	Q8IYB3	SRRM1	P42345	MTOR	S171	R168Q	168	Missense	distal	-3	no	9.699	9.090	EPSD	GDSC;CCLE	6.822	Down-regulation
Atypical_PIKK_FRAP_MTOR_ST	Q8IYB3	SRRM1	P42345	MTOR	S171	R168W	168	Missense	distal	-3	no	9.699	9.483	EPSD	GDSC;CCLE	6.822	Down-regulation
Atypical_PIKK_FRAP_MTOR_ST	Q8IYB3	SRRM1	P42345	MTOR	S171	R175H	175	Missense	distal	4	no	9.699	9.439	EPSD	GDSC;CCLE	6.822	Down-regulation
Atypical_PIKK_FRAP_MTOR_ST	Q8IYB3	SRRM1	P42345	MTOR	S179	R175H	175	Missense	distal	-4	no	12.220	11.027	EPSD	GDSC;CCLE	6.822	Down-regulation
Atypical_PIKK_FRAP_MTOR_ST	Q8IYB3	SRRM1	P42345	MTOR	S181	R175H	175	Missense	distal	-6	no	7.856	7.050	EPSD	GDSC;CCLE	6.822	Down-regulation
Atypical_PIKK_FRAP_MTOR_ST	Q8IYB3	SRRM1	P42345	MTOR	S292	R289Q	289	Missense	distal	-3	no	10.554	9.945	EPSD	GDSC	6.822	Down-regulation
Atypical_PIKK_FRAP_MTOR_ST	Q8IYB3	SRRM1	P42345	MTOR	S310	S308P	308	Missense	proximal	-2	no	9.567	9.923	EPSD	GDSC	6.822	Up-regulation
Atypical_PIKK_FRAP_MTOR_ST	Q8IYB3	SRRM1	P42345	MTOR	S380	T385I	385	Missense	distal	5	no	7.314	8.214	EPSD	GDSC;CCLE	6.822	Up-regulation
Atypical_PIKK_FRAP_MTOR_ST	Q8IYB3	SRRM1	P42345	MTOR	S389	T385I	385	Missense	distal	-4	no	11.652	11.228	EPSD	GDSC;CCLE	6.822	Down-regulation
Atypical_PIKK_FRAP_MTOR_ST	Q8IYB3	SRRM1	P42345	MTOR	S431	R427H	427	Missense	distal	-4	no	8.122	6.928	EPSD	GDSC	6.822	Down-regulation
Atypical_PIKK_FRAP_MTOR_ST	Q8IYB3	SRRM1	P42345	MTOR	S450	E446*	446	Missense	distal	-4	no	8.471	8.177	EPSD	GDSC	6.822	Down-regulation
Atypical_PIKK_FRAP_MTOR_ST	Q8IYB3	SRRM1	P42345	MTOR	S452	E446*	446	Missense	distal	-6	no	8.651	7.853	EPSD	GDSC	6.822	Down-regulation
Atypical_PIKK_FRAP_MTOR_ST	Q8IYB3	SRRM1	P42345	MTOR	S524	R520Q	520	Missense	distal	-4	no	11.164	10.667	EPSD	GDSC;CCLE	6.822	Down-regulation
Atypical_PIKK_FRAP_MTOR_ST	Q8IYB3	SRRM1	P42345	MTOR	S530	P533Q	533	Missense	distal	3	no	8.980	7.449	EPSD	GDSC;CCLE	6.822	Down-regulation
Atypical_PIKK_FRAP_MTOR_ST	Q8IYB3	SRRM1	P42345	MTOR	S532	P533Q	533	Missense	proximal	1	no	8.323	-0.291	EPSD	GDSC;CCLE	6.822	Loss
Atypical_PIKK_FRAP_MTOR_ST	Q8IYB3	SRRM1	P42345	MTOR	S541	R543C	543	Missense	proximal	2	no	7.464	7.630	EPSD	GDSC	6.822	Up-regulation
Atypical_PIKK_FRAP_MTOR_ST	Q8IYB3	SRRM1	P42345	MTOR	S549	R543C	543	Missense	distal	-6	no	13.097	13.224	EPSD	GDSC	6.822	Up-regulation
Atypical_PIKK_FRAP_MTOR_ST	Q8IYB3	SRRM1	P42345	MTOR	S551	R557M	557	Missense	distal	6	no	8.444	8.883	EPSD	GDSC	6.822	Up-regulation
Atypical_PIKK_FRAP_MTOR_ST	Q8IYB3	SRRM1	P42345	MTOR	S560	R557M	557	Missense	distal	-3	no	9.545	8.346	EPSD	GDSC	6.822	Down-regulation
Atypical_PIKK_FRAP_MTOR_ST	Q8IYB3	SRRM1	P42345	MTOR	S562	R557M	557	Missense	distal	-5	no	7.199	7.051	EPSD	GDSC	6.822	Down-regulation
Atypical_PIKK_FRAP_MTOR_ST	Q8IYB3	SRRM1	P42345	MTOR	T572	R570H	570	Missense	proximal	-2	no	7.638	7.407	EPSD;PhosphoSitePlus	GDSC	6.822	Down-regulation
Atypical_PIKK_FRAP_MTOR_ST	Q8IYB3	SRRM1	P42345	MTOR	T574	R570H	570	Missense	distal	-4	no	9.794	8.601	PhosphoSitePlus;EPSD	GDSC	6.822	Down-regulation
Atypical_PIKK_FRAP_MTOR_ST	Q8IYB3	SRRM1	P42345	MTOR	S592	P598H	598	Missense	distal	6	no	8.159	6.683	EPSD	GDSC;CCLE	6.822	Loss
Atypical_PIKK_FRAP_MTOR_ST	Q8IYB3	SRRM1	P42345	MTOR	S605	P598H	598	Missense	distal	-7	no	12.357	11.686	EPSD	GDSC;CCLE	6.822	Down-regulation
Atypical_PIKK_FRAP_MTOR_ST	Q8IYB3	SRRM1	P42345	MTOR	S616	R623*	623	Missense	distal	7	no	12.806	12.967	EPSD	GDSC	6.822	Up-regulation
Atypical_PIKK_FRAP_MTOR_ST	Q8IYB3	SRRM1	P42345	MTOR	S626	R623*	623	Missense	distal	-3	no	7.806	8.044	EPSD	GDSC	6.822	Up-regulation
Atypical_PIKK_FRAP_MTOR_ST	Q8IYB3	SRRM1	P42345	MTOR	S628	R623*	623	Missense	distal	-5	no	9.864	10.083	EPSD	GDSC	6.822	Up-regulation
Atypical_PIKK_FRAP_MTOR_ST	Q8IYB3	SRRM1	P42345	MTOR	S636	H637P	637	Missense	proximal	1	no	-16.723	10.468	EPSD	GDSC	6.822	Gain
Atypical_PIKK_FRAP_MTOR_ST	Q8IYB3	SRRM1	P42345	MTOR	S638	H637P	637	Missense	proximal	-1	no	11.852	11.904	EPSD	GDSC	6.822	Up-regulation
Atypical_PIKK_FRAP_MTOR_ST	Q8IYB3	SRRM1	P42345	MTOR	S646	P647L	647	Missense	proximal	1	no	9.843	3.873	EPSD	GDSC	6.822	Loss
Atypical_PIKK_FRAP_MTOR_ST	Q8IYB3	SRRM1	P42345	MTOR	S685	P688L	688	Missense	distal	3	no	10.720	8.465	EPSD	GDSC;CCLE	6.822	Down-regulation
Atypical_PIKK_FRAP_MTOR_ST	Q8IYB3	SRRM1	P42345	MTOR	S705	S706P	706	Missense	proximal	1	no	3.658	12.182	EPSD	GDSC;CCLE	6.822	Gain
Atypical_PIKK_FRAP_MTOR_ST	Q8IYB3	SRRM1	P42345	MTOR	S713	S706P	706	Missense	distal	-7	no	9.994	9.557	EPSD	GDSC;CCLE	6.822	Down-regulation
Atypical_PIKK_FRAP_MTOR_ST	Q8IYB3	SRRM1	P42345	MTOR	S715	R722T	722	Missense	distal	7	no	11.835	10.097	EPSD	GDSC	6.822	Down-regulation
Atypical_PIKK_FRAP_MTOR_ST	Q8IYB3	SRRM1	P42345	MTOR	T727	R722T	722	Missense	distal	-5	no	10.270	10.135	EPSD	GDSC	6.822	Down-regulation
Atypical_PIKK_FRAP_MTOR_ST	Q8IYB3	SRRM1	P42345	MTOR	S738	S740R	740	Missense	proximal	2	no	9.279	7.566	EPSD	GDSC;CCLE	6.822	Down-regulation
Atypical_PIKK_FRAP_MTOR_ST	Q8IYB3	SRRM1	P42345	MTOR	S740	S740R	740	Missense	central	0	yes	8.098	0.000	EPSD	GDSC;CCLE	6.822	Loss
Atypical_PIKK_FRAP_MTOR_ST	Q8IYB3	SRRM1	P42345	MTOR	S756	K762E	762	Missense	distal	6	no	10.971	11.876	EPSD	GDSC;CCLE	6.822	Up-regulation
Atypical_PIKK_FRAP_MTOR_ST	Q8IYB3	SRRM1	P42345	MTOR	S756	V753A	753	Missense	distal	-3	no	10.971	10.342	EPSD	GDSC;CCLE	6.822	Down-regulation
Atypical_PIKK_FRAP_MTOR_ST	Q8IYB3	SRRM1	P42345	MTOR	S769	K762E	762	Missense	distal	-7	no	6.891	7.100	EPSD	GDSC;CCLE	6.822	Up-regulation
Atypical_PIKK_FRAP_MTOR_ST	P51397	DAP	P42345	MTOR	S49	P53S	53	Missense	distal	4	no	6.595	6.850	EPSD	GDSC	6.822	Gain
Atypical_PIKK_FRAP_MTOR_ST	P51397	DAP	P42345	MTOR	S51	P53S	53	Missense	proximal	2	no	7.608	7.114	PhosphoSitePlus	GDSC	6.822	Down-regulation
Atypical_PIKK_FRAP_MTOR_ST	O95817	BAG3	P42345	MTOR	T62	G68A	68	Missense	distal	6	no	10.509	9.928	EPSD	GDSC;CCLE	6.822	Down-regulation
Atypical_PIKK_FRAP_MTOR_ST	O95817	BAG3	P42345	MTOR	S173	G167R	167	Missense	distal	-6	no	9.376	9.361	EPSD	GDSC;CCLE	6.822	Down-regulation
Atypical_PIKK_FRAP_MTOR_ST	O95817	BAG3	P42345	MTOR	S181	S187N	187	Missense	distal	6	no	8.827	7.594	EPSD	GDSC;CCLE	6.822	Down-regulation
Atypical_PIKK_FRAP_MTOR_ST	O95817	BAG3	P42345	MTOR	S207	H212R	212	Missense	distal	5	no	7.046	6.741	EPSD	GDSC;CCLE	6.822	Loss
Atypical_PIKK_FRAP_MTOR_ST	O95817	BAG3	P42345	MTOR	S264	F266S	266	Missense	proximal	2	no	10.328	12.062	EPSD	GDSC;CCLE	6.822	Up-regulation
Atypical_PIKK_FRAP_MTOR_ST	O95817	BAG3	P42345	MTOR	S269	R276Q	276	Missense	distal	7	no	7.798	7.398	EPSD	GDSC	6.822	Down-regulation
Atypical_PIKK_FRAP_MTOR_ST	O95817	BAG3	P42345	MTOR	S269	F266S	266	Missense	distal	-3	no	7.798	7.727	EPSD	GDSC;CCLE	6.822	Down-regulation
Atypical_PIKK_FRAP_MTOR_ST	O95817	BAG3	P42345	MTOR	S279	R276Q	276	Missense	distal	-3	no	12.887	12.278	EPSD	GDSC	6.822	Down-regulation
Atypical_PIKK_FRAP_MTOR_ST	O95817	BAG3	P42345	MTOR	S291	V298M	298	Missense	distal	7	no	11.061	10.688	EPSD	GDSC	6.822	Down-regulation
Atypical_PIKK_FRAP_MTOR_ST	O95817	BAG3	P42345	MTOR	S377	P380S	380	Missense	distal	3	no	9.016	9.030	EPSD	GDSC	6.822	Up-regulation
Atypical_PIKK_FRAP_MTOR_ST	O95817	BAG3	P42345	MTOR	S386	P380S	380	Missense	distal	-6	no	10.169	10.149	EPSD	GDSC	6.822	Down-regulation
Atypical_PIKK_FRAP_MTOR_ST	O95817	BAG3	P42345	MTOR	T406	G411R	411	Missense	distal	5	no	9.329	9.659	EPSD	GDSC;CCLE	6.822	Up-regulation
Atypical_PIKK_FRAP_MTOR_ST	Q86TB9	PATL1	P42345	MTOR	T194	V201A	201	Missense	distal	7	no	11.270	10.331	EPSD	GDSC	6.822	Down-regulation
Atypical_PIKK_FRAP_MTOR_ST	Q86TB9	PATL1	P42345	MTOR	T194	G193C	193	Missense	proximal	-1	no	11.270	11.288	EPSD	GDSC;CCLE	6.822	Up-regulation
Atypical_PIKK_FRAP_MTOR_ST	Q86TB9	PATL1	P42345	MTOR	S233	M232I	232	Missense	proximal	-1	no	11.026	10.893	EPSD	GDSC;CCLE	6.822	Down-regulation
Atypical_PIKK_FRAP_MTOR_ST	Q86TB9	PATL1	P42345	MTOR	S291	L293F	293	Missense	proximal	2	no	10.900	9.360	EPSD	GDSC	6.822	Down-regulation
Atypical_PIKK_FRAP_MTOR_ST	Q86TB9	PATL1	P42345	MTOR	S291	G287V	287	Missense	distal	-4	no	10.900	10.784	EPSD	GDSC;CCLE	6.822	Down-regulation
Atypical_PIKK_FRAP_MTOR_ST	Q86TB9	PATL1	P42345	MTOR	S546	P552A	552	Missense	distal	6	no	8.237	7.616	EPSD	GDSC;CCLE	6.822	Down-regulation
Atypical_PIKK_FRAP_MTOR_ST	Q13322	GRB10	P42345	MTOR	S150	P152A	152	Missense	proximal	2	no	8.664	7.406	EPSD	GDSC	6.822	Down-regulation
Atypical_PIKK_FRAP_MTOR_ST	Q13322	GRB10	P42345	MTOR	T155	P152A	152	Missense	distal	-3	no	10.158	10.097	EPSD;PhosphoSitePlus	GDSC	6.822	Down-regulation
Atypical_PIKK_FRAP_MTOR_ST	Q13322	GRB10	P42345	MTOR	T155	P160T	160	Missense	distal	5	no	10.158	9.647	EPSD;PhosphoSitePlus	GDSC;CCLE	6.822	Down-regulation
Atypical_PIKK_FRAP_MTOR_ST	Q13322	GRB10	P42345	MTOR	S428	E429K	429	Missense	proximal	1	no	8.085	5.337	PhosphoSitePlus;EPSD	GDSC;CCLE	6.822	Loss
Atypical_PIKK_FRAP_MTOR_ST	Q13322	GRB10	P42345	MTOR	S476	P477L	477	Missense	proximal	1	no	11.572	5.603	EPSD;PhosphoSitePlus	GDSC;CCLE	6.822	Loss
Atypical_PIKK_FRAP_MTOR_ST	Q13322	GRB10	P42345	MTOR	S476	Q475*	475	Missense	proximal	-1	no	11.572	11.656	EPSD;PhosphoSitePlus	GDSC	6.822	Up-regulation
Atypical_PIKK_FRAP_MTOR_ST	O96018	APBA3	P42345	MTOR	S9	M16I	16	Missense	distal	7	no	9.984	10.219	EPSD	GDSC	6.822	Up-regulation
Atypical_PIKK_FRAP_MTOR_ST	O96018	APBA3	P42345	MTOR	S9	R8*	8	Missense	proximal	-1	no	9.984	10.087	EPSD	GDSC	6.822	Up-regulation
Atypical_PIKK_FRAP_MTOR_ST	P31749	AKT1	P42345	MTOR	T312	K307N	307	Missense	distal	-5	no	10.450	10.374	EPSD	GDSC;CCLE	6.822	Down-regulation
Atypical_PIKK_FRAP_MTOR_ST	P31749	AKT1	P42345	MTOR	S473	G478S	478	Missense	distal	5	no	13.336	12.674	PhosphoSitePlus;EPSD	GDSC;CCLE	6.822	Down-regulation
Atypical_PIKK_FRAP_MTOR_ST	P31749	AKT1	P42345	MTOR	S477	G478S	478	Missense	proximal	1	no	8.451	11.555	EPSD	GDSC;CCLE	6.822	Up-regulation
Atypical_PIKK_FRAP_MTOR_ST	Q96F24	NRBF2	P42345	MTOR	S120	Q117H	117	Missense	distal	-3	no	8.445	8.307	PhosphoSitePlus;EPSD	GDSC;CCLE	6.822	Down-regulation
Atypical_PIKK_FRAP_MTOR_ST	Q96F24	NRBF2	P42345	MTOR	S120	S113I	113	Missense	distal	-7	no	8.445	7.439	PhosphoSitePlus;EPSD	GDSC;CCLE	6.822	Down-regulation
Atypical_PIKK_FRAP_MTOR_ST	Q96F24	NRBF2	P42345	MTOR	S268	P272S	272	Missense	distal	4	no	11.864	12.120	EPSD	GDSC;CCLE	6.822	Up-regulation
Atypical_PIKK_FRAP_MTOR_ST	P62753	RPS6	P42345	MTOR	S235	S242F	242	Missense	distal	7	no	6.284	6.865	EPSD;PhosphoSitePlus	GDSC	6.822	Gain
Atypical_PIKK_FRAP_MTOR_ST	P62753	RPS6	P42345	MTOR	S236	S242F	242	Missense	distal	6	no	9.910	9.335	PhosphoSitePlus;EPSD	GDSC	6.822	Down-regulation
Atypical_PIKK_FRAP_MTOR_ST	P62753	RPS6	P42345	MTOR	S240	S242F	242	Missense	proximal	2	no	8.612	6.878	EPSD	GDSC	6.822	Down-regulation
Atypical_PIKK_FRAP_MTOR_ST	P62753	RPS6	P42345	MTOR	T241	S242F	242	Missense	proximal	1	no	8.773	10.776	EPSD	GDSC	6.822	Up-regulation
Atypical_PIKK_FRAP_MTOR_ST	P62753	RPS6	P42345	MTOR	S244	S242F	242	Missense	proximal	-2	no	10.028	10.207	EPSD	GDSC	6.822	Up-regulation
Atypical_PIKK_FRAP_MTOR_ST	Q96B36	AKT1S1	P42345	MTOR	S88	R95W	95	Missense	distal	7	no	11.772	11.386	EPSD	GDSC;CCLE	6.822	Down-regulation
Atypical_PIKK_FRAP_MTOR_ST	Q96B36	AKT1S1	P42345	MTOR	T90	R95W	95	Missense	distal	5	no	8.984	8.001	EPSD	GDSC;CCLE	6.822	Down-regulation
Atypical_PIKK_FRAP_MTOR_ST	Q96B36	AKT1S1	P42345	MTOR	S183	P185S	185	Missense	proximal	2	no	9.853	9.358	PhosphoSitePlus;EPSD	GDSC;CCLE	6.822	Down-regulation
Atypical_PIKK_FRAP_MTOR_ST	Q96B36	AKT1S1	P42345	MTOR	S183	V190I	190	Missense	distal	7	no	9.853	9.714	PhosphoSitePlus;EPSD	GDSC	6.822	Down-regulation
Atypical_PIKK_FRAP_MTOR_ST	O95747	OXSR1	P42345	MTOR	S359	P360L	360	Missense	proximal	1	no	7.588	1.619	EPSD	GDSC;CCLE	6.822	Loss
Atypical_PIKK_FRAP_MTOR_ST	O95747	OXSR1	P42345	MTOR	S359	I366L	366	Missense	distal	7	no	7.588	8.190	EPSD	GDSC;CCLE	6.822	Up-regulation
Atypical_PIKK_FRAP_MTOR_ST	Q9BRS8	LARP6	P42345	MTOR	S194	Y192C	192	Missense	proximal	-2	no	8.261	8.953	EPSD	GDSC;CCLE	6.822	Up-regulation
Atypical_PIKK_FRAP_MTOR_ST	Q9BRS8	LARP6	P42345	MTOR	S228	V230M	230	Missense	proximal	2	no	7.134	5.716	EPSD	GDSC;CCLE	6.822	Loss
Atypical_PIKK_FRAP_MTOR_ST	Q9BRS8	LARP6	P42345	MTOR	S372	F370L	370	Missense	proximal	-2	no	11.055	10.742	EPSD	GDSC;CCLE	6.822	Down-regulation
Atypical_PIKK_FRAP_MTOR_ST	Q9BRS8	LARP6	P42345	MTOR	S376	F370L	370	Missense	distal	-6	no	8.196	7.917	EPSD	GDSC;CCLE	6.822	Down-regulation
Atypical_PIKK_FRAP_MTOR_ST	Q9BRS8	LARP6	P42345	MTOR	S384	G391D	391	Missense	distal	7	no	10.186	10.363	EPSD	GDSC;CCLE	6.822	Up-regulation
Atypical_PIKK_FRAP_MTOR_ST	Q9BRS8	LARP6	P42345	MTOR	S396	G391D	391	Missense	distal	-5	no	12.077	11.965	EPSD	GDSC;CCLE	6.822	Down-regulation
Atypical_PIKK_FRAP_MTOR_ST	Q9BPZ7	MAPKAP1	P42345	MTOR	S270	K276N	276	Missense	distal	6	no	9.225	8.727	EPSD	GDSC;CCLE	6.822	Down-regulation
Atypical_PIKK_FRAP_MTOR_ST	Q9BPZ7	MAPKAP1	P42345	MTOR	S275	K276N	276	Missense	proximal	1	no	6.786	10.044	EPSD	GDSC;CCLE	6.822	Gain
Atypical_PIKK_FRAP_MTOR_ST	Q00613	HSF1	P42345	MTOR	S292	R296H	296	Missense	distal	4	no	10.886	10.626	EPSD	GDSC;CCLE	6.822	Down-regulation
Atypical_PIKK_FRAP_MTOR_ST	Q00613	HSF1	P42345	MTOR	S307	P308L	308	Missense	proximal	1	no	9.596	3.627	EPSD	GDSC	6.822	Loss
Atypical_PIKK_FRAP_MTOR_ST	Q00613	HSF1	P42345	MTOR	S307	E312A	312	Missense	distal	5	no	9.596	10.408	EPSD	GDSC	6.822	Up-regulation
Atypical_PIKK_FRAP_MTOR_ST	Q00613	HSF1	P42345	MTOR	S314	P308L	308	Missense	distal	-6	no	13.184	12.410	EPSD	GDSC	6.822	Down-regulation
Atypical_PIKK_FRAP_MTOR_ST	Q00613	HSF1	P42345	MTOR	S314	E312A	312	Missense	proximal	-2	no	13.184	13.656	EPSD	GDSC	6.822	Up-regulation
Atypical_PIKK_FRAP_MTOR_ST	Q00613	HSF1	P42345	MTOR	S363	R360Q	360	Missense	distal	-3	no	8.232	7.623	EPSD	GDSC	6.822	Down-regulation
Atypical_PIKK_FRAP_MTOR_ST	Q00613	HSF1	P42345	MTOR	S363	R360W	360	Missense	distal	-3	no	8.232	8.016	EPSD	GDSC;CCLE	6.822	Down-regulation
Atypical_PIKK_FRAP_MTOR_ST	Q00613	HSF1	P42345	MTOR	S419	S419R	419	Missense	central	0	yes	14.113	0.000	EPSD	GDSC	6.822	Loss
Atypical_PIKK_FRAP_MTOR_ST	Q00613	HSF1	P42345	MTOR	S419	S421W	421	Missense	proximal	2	no	14.113	13.292	EPSD	GDSC	6.822	Down-regulation
Atypical_PIKK_FRAP_MTOR_ST	Q00613	HSF1	P42345	MTOR	S419	V422L	422	Missense	distal	3	no	14.113	12.800	EPSD	GDSC;CCLE	6.822	Down-regulation
Atypical_PIKK_FRAP_MTOR_ST	Q00613	HSF1	P42345	MTOR	S457	S458I	458	Missense	proximal	1	no	4.333	7.798	EPSD	GDSC;CCLE	6.822	Gain
Atypical_PIKK_FRAP_MTOR_ST	Q5T4S7	UBR4	P42345	MTOR	T905	R901H	901	Missense	distal	-4	no	8.373	7.180	EPSD	GDSC	6.822	Down-regulation
Atypical_PIKK_FRAP_MTOR_ST	Q5T4S7	UBR4	P42345	MTOR	S1601	H1598L	1598	Missense	distal	-3	no	6.702	7.519	EPSD	GDSC	6.822	Gain
Atypical_PIKK_FRAP_MTOR_ST	Q5T4S7	UBR4	P42345	MTOR	S1652	E1654Q	1654	Missense	proximal	2	no	6.917	4.354	EPSD	GDSC;CCLE	6.822	Loss
Atypical_PIKK_FRAP_MTOR_ST	Q5T4S7	UBR4	P42345	MTOR	T1731	S1738C	1738	Missense	distal	7	no	8.291	9.513	EPSD	GDSC	6.822	Up-regulation
Atypical_PIKK_FRAP_MTOR_ST	Q5T4S7	UBR4	P42345	MTOR	S1762	K1769N	1769	Missense	distal	7	no	7.527	8.479	EPSD	GDSC;CCLE	6.822	Up-regulation
Atypical_PIKK_FRAP_MTOR_ST	Q5T4S7	UBR4	P42345	MTOR	S1762	S1763L	1763	Missense	proximal	1	no	7.527	10.081	EPSD	GDSC	6.822	Up-regulation
Atypical_PIKK_FRAP_MTOR_ST	Q5T4S7	UBR4	P42345	MTOR	S2885	D2888N	2888	Missense	distal	3	no	8.612	8.743	EPSD	GDSC;CCLE	6.822	Up-regulation
Atypical_PIKK_FRAP_MTOR_ST	Q5T4S7	UBR4	P42345	MTOR	S2910	E2908G	2908	Missense	proximal	-2	no	7.401	8.041	EPSD	GDSC	6.822	Up-regulation
Atypical_PIKK_FRAP_MTOR_ST	Q5T4S7	UBR4	P42345	MTOR	S3271	L3264F	3264	Missense	distal	-7	no	6.728	7.072	EPSD	GDSC	6.822	Gain
Atypical_PIKK_FRAP_MTOR_ST	Q5T4S7	UBR4	P42345	MTOR	S3316	Q3321*	3321	Missense	distal	5	no	11.730	11.886	EPSD	GDSC	6.822	Up-regulation
Atypical_PIKK_FRAP_MTOR_ST	Q5T4S7	UBR4	P42345	MTOR	S4117	R4115S	4115	Missense	proximal	-2	no	11.895	12.023	EPSD	GDSC;CCLE	6.822	Up-regulation
Atypical_PIKK_FRAP_MTOR_ST	Q5T4S7	UBR4	P42345	MTOR	S5173	P5171A	5171	Missense	proximal	-2	no	12.773	12.979	EPSD	GDSC	6.822	Up-regulation
Atypical_PIKK_FRAP_MTOR_ST	Q6PKG0	LARP1	P42345	MTOR	S291	A294V	294	Missense	distal	3	no	7.779	5.768	EPSD	GDSC	6.822	Loss
Atypical_PIKK_FRAP_MTOR_ST	Q6PKG0	LARP1	P42345	MTOR	T376	T376M	376	Missense	central	0	yes	8.746	0.000	EPSD	GDSC	6.822	Loss
Atypical_PIKK_FRAP_MTOR_ST	Q6PKG0	LARP1	P42345	MTOR	T376	R375H	375	Missense	proximal	-1	no	8.746	8.787	EPSD	GDSC	6.822	Up-regulation
Atypical_PIKK_FRAP_MTOR_ST	Q6PKG0	LARP1	P42345	MTOR	T376	N382T	382	Missense	distal	6	no	8.746	9.066	EPSD	GDSC	6.822	Up-regulation
Atypical_PIKK_FRAP_MTOR_ST	Q6PKG0	LARP1	P42345	MTOR	S774	T780I	780	Missense	distal	6	no	12.081	12.131	PhosphoSitePlus;EPSD	GDSC	6.822	Up-regulation
Atypical_PIKK_FRAP_MTOR_ST	Q6PKG0	LARP1	P42345	MTOR	S774	R778H	778	Missense	distal	4	no	12.081	11.822	PhosphoSitePlus;EPSD	GDSC	6.822	Down-regulation
Atypical_PIKK_FRAP_MTOR_ST	Q6PKG0	LARP1	P42345	MTOR	S774	R781M	781	Missense	distal	7	no	12.081	11.428	PhosphoSitePlus;EPSD	GDSC	6.822	Down-regulation
Atypical_PIKK_FRAP_MTOR_ST	Q6PKG0	LARP1	P42345	MTOR	T788	R784H	784	Missense	distal	-4	no	8.100	6.907	EPSD	GDSC	6.822	Down-regulation
Atypical_PIKK_FRAP_MTOR_ST	Q6PKG0	LARP1	P42345	MTOR	T788	R781M	781	Missense	distal	-7	no	8.100	8.271	EPSD	GDSC	6.822	Up-regulation
Atypical_PIKK_FRAP_MTOR_ST	Q6PKG0	LARP1	P42345	MTOR	S823	S824L	824	Missense	proximal	1	no	5.498	8.053	EPSD	GDSC	6.822	Gain
Atypical_PIKK_FRAP_MTOR_ST	Q6PKG0	LARP1	P42345	MTOR	S851	T856M	856	Missense	distal	5	no	13.713	13.977	EPSD	GDSC	6.822	Up-regulation
Atypical_PIKK_FRAP_MTOR_ST	Q9H5H4	ZNF768	P42345	MTOR	S97	R103G	103	Missense	distal	6	no	11.915	13.667	EPSD	GDSC;CCLE	6.822	Up-regulation
Atypical_PIKK_FRAP_MTOR_ST	Q9H5H4	ZNF768	P42345	MTOR	S104	D108H	108	Missense	distal	4	no	12.580	11.818	EPSD	GDSC;CCLE	6.822	Down-regulation
Atypical_PIKK_FRAP_MTOR_ST	Q9H5H4	ZNF768	P42345	MTOR	S104	R103G	103	Missense	proximal	-1	no	12.580	12.735	EPSD	GDSC;CCLE	6.822	Up-regulation
Atypical_PIKK_FRAP_MTOR_ST	Q9H5H4	ZNF768	P42345	MTOR	S111	D108H	108	Missense	distal	-3	no	10.214	9.688	EPSD	GDSC;CCLE	6.822	Down-regulation
Atypical_PIKK_FRAP_MTOR_ST	Q9H5H4	ZNF768	P42345	MTOR	S125	Y128C	128	Missense	distal	3	no	6.898	5.271	EPSD	GDSC;CCLE	6.822	Loss
Atypical_PIKK_FRAP_MTOR_ST	Q9H5H4	ZNF768	P42345	MTOR	S132	Y128C	128	Missense	distal	-4	no	9.467	8.272	EPSD	GDSC;CCLE	6.822	Down-regulation
Atypical_PIKK_FRAP_MTOR_ST	Q9H5H4	ZNF768	P42345	MTOR	S274	T275P	275	Missense	proximal	1	no	9.588	15.860	EPSD	GDSC;CCLE	6.822	Up-regulation
Atypical_PIKK_FRAP_MTOR_ST	Q9H5H4	ZNF768	P42345	MTOR	S274	G267R	267	Missense	distal	-7	no	9.588	9.391	EPSD	GDSC;CCLE	6.822	Down-regulation
Atypical_PIKK_FRAP_MTOR_ST	Q9H5H4	ZNF768	P42345	MTOR	S442	R449H	449	Missense	distal	7	no	14.328	14.171	EPSD	GDSC	6.822	Down-regulation
Atypical_PIKK_FRAP_MTOR_ST	Q9H5H4	ZNF768	P42345	MTOR	S442	S442L	442	Missense	central	0	yes	14.328	0.000	EPSD	GDSC;CCLE	6.822	Loss
Atypical_PIKK_FRAP_MTOR_ST	Q9H063	MAF1	P42345	MTOR	S68	S73G	73	Missense	distal	5	no	10.497	11.159	EPSD;PhosphoSitePlus	GDSC	6.822	Up-regulation
Atypical_PIKK_FRAP_MTOR_ST	Q9Y2J4	AMOTL2	P42345	MTOR	S540	R547*	547	Missense	distal	7	no	11.791	11.951	EPSD	GDSC	6.822	Up-regulation
Atypical_PIKK_FRAP_MTOR_ST	Q9Y2J4	AMOTL2	P42345	MTOR	S602	D595H	595	Missense	distal	-7	no	10.857	9.504	EPSD	GDSC;CCLE	6.822	Down-regulation
Atypical_PIKK_FRAP_MTOR_ST	Q9Y2J4	AMOTL2	P42345	MTOR	S602	R600*	600	Missense	proximal	-2	no	10.857	9.760	EPSD	GDSC	6.822	Down-regulation
Atypical_PIKK_FRAP_MTOR_ST	Q9Y2J4	AMOTL2	P42345	MTOR	S602	P607L	607	Missense	distal	5	no	10.857	12.230	EPSD	GDSC;CCLE	6.822	Up-regulation
Atypical_PIKK_FRAP_MTOR_ST	Q9Y2J4	AMOTL2	P42345	MTOR	S602	Q604H	604	Missense	proximal	2	no	10.857	10.491	EPSD	GDSC	6.822	Down-regulation
Atypical_PIKK_FRAP_MTOR_ST	Q9Y2J4	AMOTL2	P42345	MTOR	S602	H601Q	601	Missense	proximal	-1	no	10.857	10.834	EPSD	GDSC	6.822	Down-regulation
Atypical_PIKK_FRAP_MTOR_ST	Q9Y2J4	AMOTL2	P42345	MTOR	S606	R600*	600	Missense	distal	-6	no	8.561	7.571	EPSD	GDSC	6.822	Down-regulation
Atypical_PIKK_FRAP_MTOR_ST	Q9Y2J4	AMOTL2	P42345	MTOR	S606	P607L	607	Missense	proximal	1	no	8.561	2.592	EPSD	GDSC;CCLE	6.822	Loss
Atypical_PIKK_FRAP_MTOR_ST	Q9Y2J4	AMOTL2	P42345	MTOR	S606	Q604H	604	Missense	proximal	-2	no	8.561	7.991	EPSD	GDSC	6.822	Down-regulation
Atypical_PIKK_FRAP_MTOR_ST	Q9Y2J4	AMOTL2	P42345	MTOR	S606	H601Q	601	Missense	distal	-5	no	8.561	8.471	EPSD	GDSC	6.822	Down-regulation
Atypical_PIKK_FRAP_MTOR_ST	Q9Y2J4	AMOTL2	P42345	MTOR	S609	P607L	607	Missense	proximal	-2	no	7.344	6.853	EPSD	GDSC;CCLE	6.822	Down-regulation
Atypical_PIKK_FRAP_MTOR_ST	Q9Y2J4	AMOTL2	P42345	MTOR	S609	Q604H	604	Missense	distal	-5	no	7.344	7.433	EPSD	GDSC	6.822	Up-regulation
Atypical_PIKK_FRAP_MTOR_ST	Q9Y2J4	AMOTL2	P42345	MTOR	S661	L662P	662	Missense	proximal	1	no	1.124	7.093	EPSD	GDSC;CCLE	6.822	Gain
Atypical_PIKK_FRAP_MTOR_ST	P04198	MYCN	P42345	MTOR	T58	L61P	61	Missense	distal	3	no	4.980	7.235	EPSD	GDSC;CCLE	6.822	Gain
Atypical_PIKK_FRAP_MTOR_ST	P04198	MYCN	P42345	MTOR	S62	L61P	61	Missense	proximal	-1	no	11.056	11.190	PhosphoSitePlus	GDSC;CCLE	6.822	Up-regulation
Atypical_PIKK_FRAP_MTOR_ST	P04198	MYCN	P42345	MTOR	S369	R373*	373	Missense	distal	4	no	8.029	8.163	EPSD	GDSC	6.822	Up-regulation
Atypical_PIKK_FRAP_MTOR_ST	P04198	MYCN	P42345	MTOR	S371	R373*	373	Missense	proximal	2	no	9.494	4.717	EPSD	GDSC	6.822	Loss
Atypical_PIKK_FRAP_MTOR_ST	P04198	MYCN	P42345	MTOR	S377	R373*	373	Missense	distal	-4	no	7.775	7.245	EPSD	GDSC	6.822	Down-regulation
Atypical_PIKK_FRAP_MTOR_ST	P04198	MYCN	P42345	MTOR	S377	R384S	384	Missense	distal	7	no	7.775	6.982	EPSD	GDSC;CCLE	6.822	Down-regulation
Atypical_PIKK_FRAP_MTOR_ST	Q9H4A3	WNK1	P42345	MTOR	S167	L171F	171	Missense	distal	4	no	7.875	8.270	EPSD	GDSC;CCLE	6.822	Up-regulation
Atypical_PIKK_FRAP_MTOR_ST	Q9H4A3	WNK1	P42345	MTOR	S1220	L1223F	1223	Missense	distal	3	no	4.873	7.546	EPSD	GDSC;CCLE	6.822	Gain
Atypical_PIKK_FRAP_MTOR_ST	Q9H4A3	WNK1	P42345	MTOR	S1299	S1300F	1300	Missense	proximal	1	no	5.808	7.811	EPSD	GDSC;CCLE	6.822	Gain
Atypical_PIKK_FRAP_MTOR_ST	Q9H4A3	WNK1	P42345	MTOR	S1902	P1907L	1907	Missense	distal	5	no	6.512	7.885	EPSD	GDSC	6.822	Gain
Atypical_PIKK_FRAP_MTOR_ST	Q9H4A3	WNK1	P42345	MTOR	S2188	P2184L	2184	Missense	distal	-4	no	12.014	11.828	EPSD	GDSC;CCLE	6.822	Down-regulation
Atypical_PIKK_FRAP_MTOR_ST	Q9H4A3	WNK1	P42345	MTOR	S2188	L2182F	2182	Missense	distal	-6	no	12.014	12.294	EPSD	GDSC;CCLE	6.822	Up-regulation
Other_NEK_NEK6_NEK6_ST	O95235	KIF20A	Q9HC98	NEK6	S104	D103N	103	Missense	proximal	-1	no	90.928	89.803	EPSD	GDSC;CCLE	73.015	Down-regulation
Other_NEK_NEK6_NEK6_ST	O95235	KIF20A	Q9HC98	NEK6	S489	P486L	486	Missense	distal	-3	no	73.271	79.704	EPSD	GDSC;CCLE	73.015	Up-regulation
Other_NEK_NEK6_NEK6_ST	Q08345	DDR1	Q9HC98	NEK6	S788	D795E	795	Missense	distal	7	no	101.878	102.818	PhosphoSitePlus	GDSC;CCLE	73.015	Up-regulation
Other_NEK_NEK6_NEK6_ST	Q96AP0	ACD	Q9HC98	NEK6	S435	R437C	437	Missense	proximal	2	no	80.738	81.010	EPSD	GDSC;CCLE	73.015	Up-regulation
Other_NEK_NEK6_NEK6_ST	Q08999	RBL2	Q9HC98	NEK6	T421	T423M	423	Missense	proximal	2	no	84.338	86.907	EPSD	GDSC;CCLE	73.015	Up-regulation
Other_NEK_NEK6_NEK6_ST	Q08999	RBL2	Q9HC98	NEK6	S861	I868M	868	Missense	distal	7	no	86.088	85.785	EPSD	GDSC	73.015	Down-regulation
Other_NEK_NEK6_NEK6_ST	Q08999	RBL2	Q9HC98	NEK6	S1035	M1029I	1029	Missense	distal	-6	no	73.595	73.568	EPSD	GDSC	73.015	Down-regulation
Other_NEK_NEK6_NEK6_ST	Q08999	RBL2	Q9HC98	NEK6	S1080	Y1076*	1076	Missense	distal	-4	no	78.289	77.948	EPSD	GDSC	73.015	Down-regulation
Other_NEK_NEK6_NEK6_ST	P52948	NUP98	Q9HC98	NEK6	S231	L227F	227	Missense	distal	-4	no	73.361	72.703	EPSD	GDSC	73.015	Loss
Other_NEK_NEK6_NEK6_ST	P52948	NUP98	Q9HC98	NEK6	S231	S230A	230	Missense	proximal	-1	no	73.361	73.122	EPSD	GDSC	73.015	Down-regulation
Other_NEK_NEK6_NEK6_ST	P52948	NUP98	Q9HC98	NEK6	S839	S839*	839	Missense	central	0	yes	111.564	0.000	EPSD	GDSC	73.015	Loss
Other_NEK_NEK6_NEK6_ST	P52732	KIF11	Q9HC98	NEK6	S323	R329K	329	Missense	distal	6	no	81.545	82.087	EPSD	GDSC;CCLE	73.015	Up-regulation
Other_NEK_NEK6_NEK6_ST	P40763	STAT3	Q9HC98	NEK6	T433	E434K	434	Missense	proximal	1	no	79.952	80.245	EPSD	GDSC;CCLE	73.015	Up-regulation
Other_NEK_NEK6_NEK6_ST	Q05586	GRIN1	Q9HC98	NEK6	S14	A21T	21	Missense	distal	7	no	74.181	73.634	EPSD	GDSC;CCLE	73.015	Down-regulation
Other_NEK_NEK6_NEK6_ST	Q05586	GRIN1	Q9HC98	NEK6	T122	T123N	123	Missense	proximal	1	no	83.571	82.905	EPSD	GDSC;CCLE	73.015	Down-regulation
Other_NEK_NEK6_NEK6_ST	Q05586	GRIN1	Q9HC98	NEK6	T442	S443L	443	Missense	proximal	1	no	79.464	79.261	EPSD	GDSC	73.015	Down-regulation
Other_NEK_NEK6_NEK6_ST	Q05586	GRIN1	Q9HC98	NEK6	S446	S443L	443	Missense	distal	-3	no	-27.480	74.703	EPSD	GDSC	73.015	Gain
Other_NEK_NEK6_NEK6_ST	P0DMV8	HSPA1A	Q9HC98	NEK6	T14	G8S	8	Missense	distal	-6	no	82.835	82.884	EPSD	GDSC;CCLE	73.015	Up-regulation
Other_NEK_NEK6_NEK6_ST	P0DMV8	HSPA1A	Q9HC98	NEK6	T66	A60V	60	Missense	distal	-6	no	104.275	104.297	PhosphoSitePlus	GDSC	73.015	Up-regulation
Other_NEK_NEK6_NEK6_ST	P0DMV8	HSPA1A	Q9HC98	NEK6	S608	G615S	615	Missense	distal	7	no	74.623	75.071	EPSD	GDSC;CCLE	73.015	Up-regulation
CK1_CK1_CK1-A_CSNK1A1_ST	P55316	FOXG1	P48729	CSNK1A1	S228	S228P	228	Missense	central	0	yes	23.055	0.000	EPSD	GDSC;CCLE	20.411	Loss
CK1_CK1_CK1-A_CSNK1A1_ST	Q13148	TARDBP	P48729	CSNK1A1	S91	V96M	96	Missense	distal	5	no	21.307	21.073	EPSD;PhosphoSitePlus	GDSC;CCLE	20.411	Down-regulation
CK1_CK1_CK1-A_CSNK1A1_ST	Q13148	TARDBP	P48729	CSNK1A1	S183	S190R	190	Missense	distal	7	no	23.255	23.362	EPSD;PhosphoSitePlus	GDSC;CCLE	20.411	Up-regulation
CK1_CK1_CK1-A_CSNK1A1_ST	Q13148	TARDBP	P48729	CSNK1A1	S242	C244G	244	Missense	proximal	2	no	26.009	27.339	EPSD;PhosphoSitePlus	GDSC;CCLE	20.411	Up-regulation
CK1_CK1_CK1-A_CSNK1A1_ST	Q13148	TARDBP	P48729	CSNK1A1	S242	D236N	236	Missense	distal	-6	no	26.009	24.729	EPSD;PhosphoSitePlus	GDSC;CCLE	20.411	Down-regulation
CK1_CK1_CK1-A_CSNK1A1_ST	Q13148	TARDBP	P48729	CSNK1A1	S387	A388V	388	Missense	proximal	1	no	21.016	21.038	EPSD;PhosphoSitePlus	GDSC;CCLE	20.411	Up-regulation
CK1_CK1_CK1-A_CSNK1A1_ST	Q13148	TARDBP	P48729	CSNK1A1	S389	A388V	388	Missense	proximal	-1	no	24.096	23.494	EPSD;PhosphoSitePlus	GDSC;CCLE	20.411	Down-regulation
CK1_CK1_CK1-A_CSNK1A1_ST	Q13148	TARDBP	P48729	CSNK1A1	S403	G400D	400	Missense	distal	-3	no	21.283	23.346	EPSD;PhosphoSitePlus	GDSC;CCLE	20.411	Up-regulation
CK1_CK1_CK1-A_CSNK1A1_ST	Q13148	TARDBP	P48729	CSNK1A1	S407	G400D	400	Missense	distal	-7	no	22.948	22.157	EPSD;PhosphoSitePlus	GDSC;CCLE	20.411	Down-regulation
CK1_CK1_CK1-A_CSNK1A1_ST	Q9Y2W7	KCNIP3	P48729	CSNK1A1	S14	A10T	10	Missense	distal	-4	no	21.452	21.417	EPSD	GDSC;CCLE	20.411	Down-regulation
CK1_CK1_CK1-A_CSNK1A1_ST	Q9BXL7	CARD11	P48729	CSNK1A1	S537	A534D	534	Missense	distal	-3	no	17.548	22.375	EPSD	GDSC	20.411	Gain
CK1_CK1_CK1-A_CSNK1A1_ST	Q9BXL7	CARD11	P48729	CSNK1A1	S538	A534D	534	Missense	distal	-4	no	19.459	22.054	EPSD	GDSC	20.411	Gain
CK1_CK1_CK1-A_CSNK1A1_ST	Q9BXL7	CARD11	P48729	CSNK1A1	S541	G540V	540	Missense	proximal	-1	no	22.394	20.962	EPSD	GDSC;CCLE	20.411	Down-regulation
CK1_CK1_CK1-A_CSNK1A1_ST	Q9BXL7	CARD11	P48729	CSNK1A1	S541	I544L	544	Missense	distal	3	no	22.394	19.898	EPSD	GDSC	20.411	Loss
CK1_CK1_CK1-A_CSNK1A1_ST	Q9BXL7	CARD11	P48729	CSNK1A1	S541	A534D	534	Missense	distal	-7	no	22.394	22.132	EPSD	GDSC	20.411	Down-regulation
CK1_CK1_CK1-A_CSNK1A1_ST	Q9BXL7	CARD11	P48729	CSNK1A1	S541	A534T	534	Missense	distal	-7	no	22.394	21.422	EPSD	GDSC	20.411	Down-regulation
CK1_CK1_CK1-A_CSNK1A1_ST	Q9BXL7	CARD11	P48729	CSNK1A1	S618	H617R	617	Missense	proximal	-1	no	21.130	21.811	EPSD	GDSC;CCLE	20.411	Up-regulation
CK1_CK1_CK1-A_CSNK1A1_ST	Q9BXL7	CARD11	P48729	CSNK1A1	S621	H617R	617	Missense	distal	-4	no	20.800	22.840	EPSD	GDSC;CCLE	20.411	Up-regulation
CK1_CK1_CK1-A_CSNK1A1_ST	Q9BXL7	CARD11	P48729	CSNK1A1	S622	H617R	617	Missense	distal	-5	no	22.741	23.239	EPSD	GDSC;CCLE	20.411	Up-regulation
CK1_CK1_CK1-A_CSNK1A1_ST	Q9BXL7	CARD11	P48729	CSNK1A1	S879	D882V	882	Missense	distal	3	no	23.417	20.111	EPSD	GDSC;CCLE	20.411	Loss
CK1_CK1_CK1-A_CSNK1A1_ST	Q9Y4G8	RAPGEF2	P48729	CSNK1A1	S1153	S1152F	1152	Missense	proximal	-1	no	22.514	21.812	EPSD	GDSC;CCLE	20.411	Down-regulation
CK1_CK1_CK1-A_CSNK1A1_ST	Q9Y4G8	RAPGEF2	P48729	CSNK1A1	S1156	S1152F	1152	Missense	distal	-4	no	21.524	19.874	EPSD	GDSC;CCLE	20.411	Loss
CK1_CK1_CK1-A_CSNK1A1_ST	Q9Y4G8	RAPGEF2	P48729	CSNK1A1	S1225	S1225N	1225	Missense	central	0	yes	20.882	0.000	EPSD	GDSC;CCLE	20.411	Loss
CK1_CK1_CK1-A_CSNK1A1_ST	Q9Y4G8	RAPGEF2	P48729	CSNK1A1	S1230	S1225N	1225	Missense	distal	-5	no	23.223	23.052	EPSD	GDSC;CCLE	20.411	Down-regulation
CK1_CK1_CK1-A_CSNK1A1_ST	P04637	TP53	P48729	CSNK1A1	S6	M1K	1	Missense	distal	-5	no	22.651	20.806	EPSD	GDSC	20.411	Down-regulation
CK1_CK1_CK1-A_CSNK1A1_ST	P17931	LGALS3	P48729	CSNK1A1	S12	L11S	11	Missense	proximal	-1	no	22.212	22.487	EPSD;PhosphoSitePlus	GDSC;CCLE	20.411	Up-regulation
CK1_CK1_CK1-A_CSNK1A1_ST	Q13009	TIAM1	P48729	CSNK1A1	S63	P62L	62	Missense	proximal	-1	no	23.913	23.629	EPSD	GDSC;CCLE	20.411	Down-regulation
CK1_CK1_CK1-A_CSNK1A1_ST	Q13009	TIAM1	P48729	CSNK1A1	S219	P220S	220	Missense	proximal	1	no	20.495	20.342	EPSD	GDSC;CCLE	20.411	Loss
CK1_CK1_CK1-A_CSNK1A1_ST	Q13009	TIAM1	P48729	CSNK1A1	S219	S224R	224	Missense	distal	5	no	20.495	20.904	EPSD	GDSC;CCLE	20.411	Up-regulation
CK1_CK1_CK1-A_CSNK1A1_ST	Q13009	TIAM1	P48729	CSNK1A1	S251	R258W	258	Missense	distal	7	no	20.260	20.636	EPSD	GDSC;CCLE	20.411	Gain
CK1_CK1_CK1-A_CSNK1A1_ST	Q13009	TIAM1	P48729	CSNK1A1	S372	G376R	376	Missense	distal	4	no	20.561	20.560	EPSD	GDSC;CCLE	20.411	Down-regulation
CK1_CK1_CK1-A_CSNK1A1_ST	Q13009	TIAM1	P48729	CSNK1A1	S372	S374C	374	Missense	proximal	2	no	20.561	19.576	EPSD	GDSC;CCLE	20.411	Loss
CK1_CK1_CK1-A_CSNK1A1_ST	Q13009	TIAM1	P48729	CSNK1A1	S373	G376R	376	Missense	distal	3	no	23.499	20.607	EPSD	GDSC;CCLE	20.411	Down-regulation
CK1_CK1_CK1-A_CSNK1A1_ST	Q13009	TIAM1	P48729	CSNK1A1	S373	S374C	374	Missense	proximal	1	no	23.499	23.294	EPSD	GDSC;CCLE	20.411	Down-regulation
CK1_CK1_CK1-A_CSNK1A1_ST	Q13009	TIAM1	P48729	CSNK1A1	S374	G376R	376	Missense	proximal	2	no	23.810	22.859	EPSD	GDSC;CCLE	20.411	Down-regulation
CK1_CK1_CK1-A_CSNK1A1_ST	Q13009	TIAM1	P48729	CSNK1A1	S374	S374C	374	Missense	central	0	yes	23.810	0.000	EPSD	GDSC;CCLE	20.411	Loss
CK1_CK1_CK1-A_CSNK1A1_ST	Q13009	TIAM1	P48729	CSNK1A1	S726	T720I	720	Missense	distal	-6	no	21.784	21.159	EPSD	GDSC;CCLE	20.411	Down-regulation
CK1_CK1_CK1-A_CSNK1A1_ST	Q13009	TIAM1	P48729	CSNK1A1	S989	D985E	985	Missense	distal	-4	no	20.497	20.061	EPSD	GDSC;CCLE	20.411	Loss
CK1_CK1_CK1-A_CSNK1A1_ST	Q13009	TIAM1	P48729	CSNK1A1	S989	E991Q	991	Missense	proximal	2	no	20.497	20.231	EPSD	GDSC;CCLE	20.411	Loss
CK1_CK1_CK1-A_CSNK1A1_ST	Q13009	TIAM1	P48729	CSNK1A1	S989	S988T	988	Missense	proximal	-1	no	20.497	20.099	EPSD	GDSC	20.411	Loss
CK1_CK1_CK1-A_CSNK1A1_ST	Q13009	TIAM1	P48729	CSNK1A1	T992	D985E	985	Missense	distal	-7	no	21.646	21.930	EPSD	GDSC;CCLE	20.411	Up-regulation
CK1_CK1_CK1-A_CSNK1A1_ST	Q13009	TIAM1	P48729	CSNK1A1	T992	E991Q	991	Missense	proximal	-1	no	21.646	21.121	EPSD	GDSC;CCLE	20.411	Down-regulation
CK1_CK1_CK1-A_CSNK1A1_ST	Q13009	TIAM1	P48729	CSNK1A1	T992	S988T	988	Missense	distal	-4	no	21.646	20.011	EPSD	GDSC	20.411	Loss
CK1_CK1_CK1-A_CSNK1A1_ST	Q12968	NFATC3	P48729	CSNK1A1	S168	S168N	168	Missense	central	0	yes	22.546	0.000	EPSD	GDSC;CCLE	20.411	Loss
CK1_CK1_CK1-A_CSNK1A1_ST	Q12968	NFATC3	P48729	CSNK1A1	S177	S177F	177	Missense	central	0	yes	22.266	0.000	EPSD	GDSC;CCLE	20.411	Loss
CK1_CK1_CK1-A_CSNK1A1_ST	Q12968	NFATC3	P48729	CSNK1A1	S181	S177F	177	Missense	distal	-4	no	22.963	21.313	EPSD	GDSC;CCLE	20.411	Down-regulation
CK1_CK1_CK1-A_CSNK1A1_ST	Q12968	NFATC3	P48729	CSNK1A1	S184	S177F	177	Missense	distal	-7	no	21.439	21.021	EPSD	GDSC;CCLE	20.411	Down-regulation
CK1_CK1_CK1-A_CSNK1A1_ST	Q12968	NFATC3	P48729	CSNK1A1	S184	Y189C	189	Missense	distal	5	no	21.439	21.336	EPSD	GDSC	20.411	Down-regulation
CK1_CK1_CK1-A_CSNK1A1_ST	Q12968	NFATC3	P48729	CSNK1A1	S742	H737Y	737	Missense	distal	-5	no	21.943	21.365	EPSD	GDSC;CCLE	20.411	Down-regulation
CK1_CK1_CK1-A_CSNK1A1_ST	Q12968	NFATC3	P48729	CSNK1A1	S1048	I1047S	1047	Missense	proximal	-1	no	23.341	22.584	EPSD	GDSC;CCLE	20.411	Down-regulation
CK1_CK1_CK1-A_CSNK1A1_ST	O60716	CTNND1	P48729	CSNK1A1	T134	T133I	133	Missense	proximal	-1	no	21.402	22.557	EPSD	GDSC;CCLE	20.411	Up-regulation
CK1_CK1_CK1-A_CSNK1A1_ST	O60716	CTNND1	P48729	CSNK1A1	S171	T177A	177	Missense	distal	6	no	21.622	21.368	EPSD	GDSC;CCLE	20.411	Down-regulation
CK1_CK1_CK1-A_CSNK1A1_ST	O60716	CTNND1	P48729	CSNK1A1	S288	D293E	293	Missense	distal	5	no	22.680	22.472	EPSD	GDSC;CCLE	20.411	Down-regulation
CK1_CK1_CK1-A_CSNK1A1_ST	O60716	CTNND1	P48729	CSNK1A1	S346	R344Q	344	Missense	proximal	-2	no	19.993	20.500	EPSD	GDSC;CCLE	20.411	Gain
CK1_CK1_CK1-A_CSNK1A1_ST	O60716	CTNND1	P48729	CSNK1A1	S349	R344Q	344	Missense	distal	-5	no	21.809	22.607	EPSD	GDSC;CCLE	20.411	Up-regulation
CK1_CK1_CK1-A_CSNK1A1_ST	O60716	CTNND1	P48729	CSNK1A1	S484	W477*	477	Missense	distal	-7	no	19.468	20.985	EPSD	GDSC	20.411	Gain
CK1_CK1_CK1-A_CSNK1A1_ST	O60716	CTNND1	P48729	CSNK1A1	S859	R858Q	858	Missense	proximal	-1	no	19.541	20.537	EPSD	GDSC	20.411	Gain
CK1_CK1_CK1-A_CSNK1A1_ST	O60716	CTNND1	P48729	CSNK1A1	S861	R858Q	858	Missense	distal	-3	no	19.814	20.769	EPSD	GDSC	20.411	Gain
CK1_CK1_CK1-A_CSNK1A1_ST	O60716	CTNND1	P48729	CSNK1A1	S862	R858Q	858	Missense	distal	-4	no	18.314	20.528	EPSD	GDSC	20.411	Gain
CK1_CK1_CK1-A_CSNK1A1_ST	O60716	CTNND1	P48729	CSNK1A1	S864	R858Q	858	Missense	distal	-6	no	22.669	22.858	EPSD	GDSC	20.411	Up-regulation
CK1_CK1_CK1-A_CSNK1A1_ST	P56817	BACE1	P48729	CSNK1A1	S59	P54T	54	Missense	distal	-5	no	22.859	22.660	EPSD	GDSC	20.411	Down-regulation
CK1_CK1_CK1-A_CSNK1A1_ST	P12830	CDH1	P48729	CSNK1A1	S838	V832M	832	Missense	distal	-6	no	23.165	24.193	EPSD	GDSC	20.411	Up-regulation
CK1_CK1_CK1-A_CSNK1A1_ST	P51532	SMARCA4	P48729	CSNK1A1	S38	G44E	44	Missense	distal	6	no	24.806	24.491	EPSD	GDSC;CCLE	20.411	Down-regulation
CK1_CK1_CK1-A_CSNK1A1_ST	P51532	SMARCA4	P48729	CSNK1A1	S122	Y120S	120	Missense	proximal	-2	no	18.804	20.847	EPSD	GDSC	20.411	Gain
CK1_CK1_CK1-A_CSNK1A1_ST	P51532	SMARCA4	P48729	CSNK1A1	S660	S655P	655	Missense	distal	-5	no	27.117	26.684	EPSD	GDSC;CCLE	20.411	Down-regulation
CK1_CK1_CK1-A_CSNK1A1_ST	P51532	SMARCA4	P48729	CSNK1A1	S662	S655P	655	Missense	distal	-7	no	21.031	20.365	EPSD	GDSC;CCLE	20.411	Loss
CK1_CK1_CK1-A_CSNK1A1_ST	P51532	SMARCA4	P48729	CSNK1A1	S695	D694E	694	Missense	proximal	-1	no	20.891	21.521	EPSD	GDSC;CCLE	20.411	Up-regulation
CK1_CK1_CK1-A_CSNK1A1_ST	P51532	SMARCA4	P48729	CSNK1A1	S699	D694E	694	Missense	distal	-5	no	25.806	25.086	EPSD	GDSC;CCLE	20.411	Down-regulation
CK1_CK1_CK1-A_CSNK1A1_ST	P51532	SMARCA4	P48729	CSNK1A1	S1570	D1569G	1569	Missense	proximal	-1	no	20.161	20.434	EPSD	GDSC	20.411	Gain
CK1_CK1_CK1-A_CSNK1A1_ST	P51532	SMARCA4	P48729	CSNK1A1	S1575	D1569G	1569	Missense	distal	-6	no	27.501	27.376	EPSD	GDSC	20.411	Down-regulation
CK1_CK1_CK1-A_CSNK1A1_ST	P16220	CREB1	P48729	CSNK1A1	S111	S111L	111	Missense	central	0	yes	24.754	0.000	PhosphoSitePlus;EPSD	GDSC;CCLE	20.411	Loss
CK1_CK1_CK1-A_CSNK1A1_ST	P16220	CREB1	P48729	CSNK1A1	S114	S111L	111	Missense	distal	-3	no	26.239	19.645	EPSD;PhosphoSitePlus	GDSC;CCLE	20.411	Loss
CK1_CK1_CK1-A_CSNK1A1_ST	P16220	CREB1	P48729	CSNK1A1	S117	S111L	111	Missense	distal	-6	no	21.395	20.501	EPSD	GDSC;CCLE	20.411	Down-regulation
CK1_CK1_CK1-A_CSNK1A1_ST	P11308	ERG	P48729	CSNK1A1	S46	A42T	42	Missense	distal	-4	no	29.392	29.357	EPSD;PhosphoSitePlus	GDSC;CCLE	20.411	Down-regulation
CK1_CK1_CK1-A_CSNK1A1_ST	P11308	ERG	P48729	CSNK1A1	S88	D90G	90	Missense	proximal	2	no	22.835	23.039	EPSD	GDSC;CCLE	20.411	Up-regulation
CK1_CK1_CK1-A_CSNK1A1_ST	P25054	APC	P48729	CSNK1A1	S98	S98I	98	Missense	central	0	yes	23.082	0.000	EPSD	GDSC;CCLE	20.411	Loss
CK1_CK1_CK1-A_CSNK1A1_ST	P25054	APC	P48729	CSNK1A1	S130	L134S	134	Missense	distal	4	no	23.805	23.775	EPSD	GDSC;CCLE	20.411	Down-regulation
CK1_CK1_CK1-A_CSNK1A1_ST	P25054	APC	P48729	CSNK1A1	S846	E853*	853	Missense	distal	7	no	27.884	28.290	EPSD	GDSC	20.411	Up-regulation
CK1_CK1_CK1-A_CSNK1A1_ST	P25054	APC	P48729	CSNK1A1	S992	Q999*	999	Missense	distal	7	no	22.129	22.404	EPSD	GDSC	20.411	Up-regulation
CK1_CK1_CK1-A_CSNK1A1_ST	P25054	APC	P48729	CSNK1A1	S1148	Q1152*	1152	Missense	distal	4	no	22.107	21.965	EPSD	GDSC	20.411	Down-regulation
CK1_CK1_CK1-A_CSNK1A1_ST	P25054	APC	P48729	CSNK1A1	S1148	E1151*	1151	Missense	distal	3	no	22.107	16.429	EPSD	GDSC	20.411	Loss
CK1_CK1_CK1-A_CSNK1A1_ST	P25054	APC	P48729	CSNK1A1	S1343	Q1338*	1338	Missense	distal	-5	no	20.865	19.971	EPSD	GDSC	20.411	Loss
CK1_CK1_CK1-A_CSNK1A1_ST	P25054	APC	P48729	CSNK1A1	S1343	S1344*	1344	Missense	proximal	1	no	20.865	20.545	EPSD	GDSC	20.411	Down-regulation
CK1_CK1_CK1-A_CSNK1A1_ST	P25054	APC	P48729	CSNK1A1	S1343	G1339R	1339	Missense	distal	-4	no	20.865	18.667	EPSD	GDSC;CCLE	20.411	Loss
CK1_CK1_CK1-A_CSNK1A1_ST	P25054	APC	P48729	CSNK1A1	S1392	S1392*	1392	Missense	central	0	yes	21.764	0.000	EPSD	GDSC	20.411	Loss
CK1_CK1_CK1-A_CSNK1A1_ST	P25054	APC	P48729	CSNK1A1	S1395	S1392*	1392	Missense	distal	-3	no	21.416	17.574	EPSD	GDSC	20.411	Loss
CK1_CK1_CK1-A_CSNK1A1_ST	P25054	APC	P48729	CSNK1A1	S1398	S1392*	1392	Missense	distal	-6	no	25.131	24.527	EPSD	GDSC	20.411	Down-regulation
CK1_CK1_CK1-A_CSNK1A1_ST	P25054	APC	P48729	CSNK1A1	S1501	G1499*	1499	Missense	proximal	-2	no	26.380	25.590	EPSD	GDSC	20.411	Down-regulation
CK1_CK1_CK1-A_CSNK1A1_ST	P25054	APC	P48729	CSNK1A1	S1504	G1499*	1499	Missense	distal	-5	no	24.414	23.153	EPSD;PhosphoSitePlus	GDSC	20.411	Down-regulation
CK1_CK1_CK1-A_CSNK1A1_ST	P25054	APC	P48729	CSNK1A1	S1505	G1499*	1499	Missense	distal	-6	no	20.965	20.221	EPSD;PhosphoSitePlus	GDSC	20.411	Loss
CK1_CK1_CK1-A_CSNK1A1_ST	P25054	APC	P48729	CSNK1A1	S1507	E1513*	1513	Missense	distal	6	no	26.279	26.136	PhosphoSitePlus;EPSD	GDSC	20.411	Down-regulation
CK1_CK1_CK1-A_CSNK1A1_ST	P25054	APC	P48729	CSNK1A1	S1510	E1513*	1513	Missense	distal	3	no	23.496	17.817	EPSD;PhosphoSitePlus	GDSC	20.411	Loss
CK1_CK1_CK1-A_CSNK1A1_ST	P25054	APC	P48729	CSNK1A1	S1864	D1871Y	1871	Missense	distal	7	no	20.267	20.558	EPSD	GDSC;CCLE	20.411	Gain
CK1_CK1_CK1-A_CSNK1A1_ST	P25054	APC	P48729	CSNK1A1	S2034	S2028T	2028	Missense	distal	-6	no	22.264	21.882	EPSD	GDSC;CCLE	20.411	Down-regulation
CK1_CK1_CK1-A_CSNK1A1_ST	P25054	APC	P48729	CSNK1A1	S2143	G2145V	2145	Missense	proximal	2	no	21.084	19.466	EPSD	GDSC;CCLE	20.411	Loss
CK1_CK1_CK1-A_CSNK1A1_ST	P25054	APC	P48729	CSNK1A1	S2143	L2150V	2150	Missense	distal	7	no	21.084	21.247	EPSD	GDSC;CCLE	20.411	Up-regulation
CK1_CK1_CK1-A_CSNK1A1_ST	P25054	APC	P48729	CSNK1A1	S2461	F2462S	2462	Missense	proximal	1	no	20.924	20.981	EPSD	GDSC;CCLE	20.411	Up-regulation
CK1_CK1_CK1-A_CSNK1A1_ST	P25054	APC	P48729	CSNK1A1	S2461	P2467L	2467	Missense	distal	6	no	20.924	21.010	EPSD	GDSC;CCLE	20.411	Up-regulation
CK1_CK1_CK1-A_CSNK1A1_ST	P25054	APC	P48729	CSNK1A1	S2466	F2462S	2462	Missense	distal	-4	no	21.188	22.838	EPSD	GDSC;CCLE	20.411	Up-regulation
CK1_CK1_CK1-A_CSNK1A1_ST	P25054	APC	P48729	CSNK1A1	S2466	P2467L	2467	Missense	proximal	1	no	21.188	21.298	EPSD	GDSC;CCLE	20.411	Up-regulation
CK1_CK1_CK1-A_CSNK1A1_ST	P25054	APC	P48729	CSNK1A1	S2572	S2575Y	2575	Missense	distal	3	no	22.288	19.483	EPSD	GDSC	20.411	Loss
CK1_CK1_CK1-A_CSNK1A1_ST	P25054	APC	P48729	CSNK1A1	S2575	S2575Y	2575	Missense	central	0	yes	24.897	0.000	EPSD	GDSC	20.411	Loss
CK1_CK1_CK1-A_CSNK1A1_ST	P25054	APC	P48729	CSNK1A1	S2580	S2575Y	2575	Missense	distal	-5	no	21.313	19.367	EPSD	GDSC	20.411	Loss
CK1_CK1_CK1-A_CSNK1A1_ST	P25054	APC	P48729	CSNK1A1	S2674	R2673G	2673	Missense	proximal	-1	no	20.899	22.062	EPSD	GDSC;CCLE	20.411	Up-regulation
CK1_CK1_CK1-A_CSNK1A1_ST	P25054	APC	P48729	CSNK1A1	S2771	A2778V	2778	Missense	distal	7	no	22.693	22.812	EPSD	GDSC	20.411	Up-regulation
CK1_CK1_CK1-A_CSNK1A1_ST	O60260	PRKN	P48729	CSNK1A1	S378	Y372*	372	Missense	distal	-6	no	22.299	22.743	PhosphoSitePlus;EPSD	GDSC	20.411	Up-regulation
CK1_CK1_CK1-A_CSNK1A1_ST	O60260	PRKN	P48729	CSNK1A1	S378	V380I	380	Missense	proximal	2	no	22.299	22.774	PhosphoSitePlus;EPSD	GDSC	20.411	Up-regulation
CK1_CK1_CK1-A_CSNK1A1_ST	P08238	HSP90AB1	P48729	CSNK1A1	S255	E257Q	257	Missense	proximal	2	no	23.176	22.910	EPSD	GDSC;CCLE	20.411	Down-regulation
CK1_CK1_CK1-A_CSNK1A1_ST	P08238	HSP90AB1	P48729	CSNK1A1	S261	E257Q	257	Missense	distal	-4	no	22.901	22.524	EPSD	GDSC;CCLE	20.411	Down-regulation
CK1_CK1_CK1-A_CSNK1A1_ST	P08238	HSP90AB1	P48729	CSNK1A1	T297	G302*	302	Missense	distal	5	no	20.976	21.114	EPSD	GDSC	20.411	Up-regulation
CK1_CK1_CK1-A_CSNK1A1_ST	P08238	HSP90AB1	P48729	CSNK1A1	S669	P673S	673	Missense	distal	4	no	25.613	25.649	EPSD	GDSC;CCLE	20.411	Up-regulation
CK1_CK1_CK1-A_CSNK1A1_ST	O75581	LRP6	P48729	CSNK1A1	S122	R118Q	118	Missense	distal	-4	no	18.583	20.797	EPSD	GDSC	20.411	Gain
CK1_CK1_CK1-A_CSNK1A1_ST	O75581	LRP6	P48729	CSNK1A1	S209	F205S	205	Missense	distal	-4	no	19.474	21.123	EPSD	GDSC;CCLE	20.411	Gain
CK1_CK1_CK1-A_CSNK1A1_ST	O75581	LRP6	P48729	CSNK1A1	S1472	T1479I	1479	Missense	distal	7	no	20.721	20.571	EPSD	GDSC	20.411	Down-regulation
CK1_CK1_CK1-A_CSNK1A1_ST	O75581	LRP6	P48729	CSNK1A1	S1475	T1479I	1479	Missense	distal	4	no	25.945	26.002	EPSD	GDSC	20.411	Up-regulation
CK1_CK1_CK1-A_CSNK1A1_ST	Q12778	FOXO1	P48729	CSNK1A1	S206	I213S	213	Missense	distal	7	no	20.936	21.027	EPSD	GDSC;CCLE	20.411	Up-regulation
CK1_CK1_CK1-A_CSNK1A1_ST	Q12778	FOXO1	P48729	CSNK1A1	S212	L219P	219	Missense	distal	7	no	24.169	24.322	EPSD	GDSC;CCLE	20.411	Up-regulation
CK1_CK1_CK1-A_CSNK1A1_ST	Q12778	FOXO1	P48729	CSNK1A1	S212	I213S	213	Missense	proximal	1	no	24.169	23.996	EPSD	GDSC;CCLE	20.411	Down-regulation
CK1_CK1_CK1-A_CSNK1A1_ST	Q12778	FOXO1	P48729	CSNK1A1	S509	A511S	511	Missense	proximal	2	no	20.770	21.600	EPSD	GDSC;CCLE	20.411	Up-regulation
CK1_CK1_CK1-A_CSNK1A1_ST	Q13501	SQSTM1	P48729	CSNK1A1	S152	E155D	155	Missense	distal	3	no	20.756	20.896	EPSD	GDSC;CCLE	20.411	Up-regulation
CK1_CK1_CK1-A_CSNK1A1_ST	Q13501	SQSTM1	P48729	CSNK1A1	S170	L166I	166	Missense	distal	-4	no	19.275	20.884	EPSD	GDSC;CCLE	20.411	Gain
CK1_CK1_CK1-A_CSNK1A1_ST	Q13501	SQSTM1	P48729	CSNK1A1	S176	S180*	180	Missense	distal	4	no	20.545	20.334	EPSD	GDSC	20.411	Loss
CK1_CK1_CK1-A_CSNK1A1_ST	Q13501	SQSTM1	P48729	CSNK1A1	S180	S180*	180	Missense	central	0	yes	26.136	0.000	EPSD	GDSC	20.411	Loss
CK1_CK1_CK1-A_CSNK1A1_ST	Q13501	SQSTM1	P48729	CSNK1A1	S182	S180*	180	Missense	proximal	-2	no	21.169	20.230	EPSD	GDSC	20.411	Loss
CK1_CK1_CK1-A_CSNK1A1_ST	Q13501	SQSTM1	P48729	CSNK1A1	S224	P220L	220	Missense	distal	-4	no	23.092	21.977	EPSD	GDSC;CCLE	20.411	Down-regulation
CK1_CK1_CK1-A_CSNK1A1_ST	Q13501	SQSTM1	P48729	CSNK1A1	S226	P220L	220	Missense	distal	-6	no	26.569	26.357	EPSD	GDSC;CCLE	20.411	Down-regulation
CK1_CK1_CK1-A_CSNK1A1_ST	Q13501	SQSTM1	P48729	CSNK1A1	S349	L356P	356	Missense	distal	7	no	22.063	22.215	PhosphoSitePlus	GDSC;CCLE	20.411	Up-regulation
CK1_CK1_CK1-A_CSNK1A1_ST	Q13501	SQSTM1	P48729	CSNK1A1	S349	Q354*	354	Missense	distal	5	no	22.063	22.638	PhosphoSitePlus	GDSC	20.411	Up-regulation
CK1_CK1_CK1-A_CSNK1A1_ST	Q13501	SQSTM1	P48729	CSNK1A1	S361	L356P	356	Missense	distal	-5	no	23.967	24.163	EPSD	GDSC;CCLE	20.411	Up-regulation
CK1_CK1_CK1-A_CSNK1A1_ST	Q13501	SQSTM1	P48729	CSNK1A1	S361	Q354*	354	Missense	distal	-7	no	23.967	23.762	EPSD	GDSC	20.411	Down-regulation
CK1_CK1_CK1-A_CSNK1A1_ST	Q13501	SQSTM1	P48729	CSNK1A1	S365	S370P	370	Missense	distal	5	no	20.464	20.712	EPSD	GDSC	20.411	Up-regulation
CK1_CK1_CK1-A_CSNK1A1_ST	P07910	HNRNPC	P48729	CSNK1A1	S182	S175F	175	Missense	distal	-7	no	21.299	20.882	EPSD	GDSC;CCLE	20.411	Down-regulation
CK1_CK1_CK1-A_CSNK1A1_ST	P07910	HNRNPC	P48729	CSNK1A1	S239	E246G	246	Missense	distal	7	no	22.141	22.288	EPSD	GDSC;CCLE	20.411	Up-regulation
CK1_CK1_CK1-A_CSNK1A1_ST	P07910	HNRNPC	P48729	CSNK1A1	S241	E246G	246	Missense	distal	5	no	22.842	23.186	EPSD	GDSC;CCLE	20.411	Up-regulation
CK1_CK1_CK1-A_CSNK1A1_ST	P07910	HNRNPC	P48729	CSNK1A1	S253	E246G	246	Missense	distal	-7	no	20.946	21.453	PhosphoSitePlus;EPSD	GDSC;CCLE	20.411	Up-regulation
CK1_CK1_CK1-A_CSNK1A1_ST	P07910	HNRNPC	P48729	CSNK1A1	S253	A257E	257	Missense	distal	4	no	20.946	21.075	PhosphoSitePlus;EPSD	GDSC	20.411	Up-regulation
CK1_CK1_CK1-A_CSNK1A1_ST	P07910	HNRNPC	P48729	CSNK1A1	S253	A257T	257	Missense	distal	4	no	20.946	20.935	PhosphoSitePlus;EPSD	GDSC;CCLE	20.411	Down-regulation
CK1_CK1_CK1-A_CSNK1A1_ST	P07910	HNRNPC	P48729	CSNK1A1	S260	A257E	257	Missense	distal	-3	no	21.130	23.482	EPSD;PhosphoSitePlus	GDSC	20.411	Up-regulation
CK1_CK1_CK1-A_CSNK1A1_ST	P07910	HNRNPC	P48729	CSNK1A1	S260	A257T	257	Missense	distal	-3	no	21.130	21.822	EPSD;PhosphoSitePlus	GDSC;CCLE	20.411	Up-regulation
CK1_CK1_CK1-A_CSNK1A1_ST	Q8TB45	DEPTOR	P48729	CSNK1A1	S15	A22G	22	Missense	distal	7	no	24.411	24.353	EPSD	GDSC	20.411	Down-regulation
CK1_CK1_CK1-A_CSNK1A1_ST	Q8TB45	DEPTOR	P48729	CSNK1A1	S17	A22G	22	Missense	distal	5	no	26.229	26.222	EPSD	GDSC	20.411	Down-regulation
CK1_CK1_CK1-A_CSNK1A1_ST	Q8TB45	DEPTOR	P48729	CSNK1A1	S19	A22G	22	Missense	distal	3	no	20.099	22.777	EPSD	GDSC	20.411	Gain
CK1_CK1_CK1-A_CSNK1A1_ST	Q04206	RELA	P48729	CSNK1A1	S205	E211V	211	Missense	distal	6	no	20.979	20.814	EPSD	GDSC	20.411	Down-regulation
CK1_CK1_CK1-A_CSNK1A1_ST	Q04206	RELA	P48729	CSNK1A1	S205	V199A	199	Missense	distal	-6	no	20.979	21.237	EPSD	GDSC;CCLE	20.411	Up-regulation
CK1_CK1_CK1-A_CSNK1A1_ST	P17181	IFNAR1	P48729	CSNK1A1	S532	T531I	531	Missense	proximal	-1	no	21.791	22.946	EPSD	GDSC	20.411	Up-regulation
CK1_CK1_CK1-A_CSNK1A1_ST	P35222	CTNNB1	P48729	CSNK1A1	S552	R549H	549	Missense	distal	-3	no	20.527	18.886	EPSD	GDSC;CCLE	20.411	Loss
CK1_CK1_CK1-A_CSNK1A1_ST	Q9H6E5	TUT1	P48729	CSNK1A1	S731	A734P	734	Missense	distal	3	no	21.360	19.324	EPSD	GDSC;CCLE	20.411	Loss
CK1_CK1_CK1-A_CSNK1A1_ST	P67809	YBX1	P48729	CSNK1A1	S176	E169A	169	Missense	distal	-7	no	22.471	22.448	PhosphoSitePlus	GDSC	20.411	Down-regulation
CK1_CK1_CK1-A_CSNK1A1_ST	P30304	CDC25A	P48729	CSNK1A1	S79	G75C	75	Missense	distal	-4	no	26.558	23.693	EPSD;PhosphoSitePlus	GDSC;CCLE	20.411	Down-regulation
CK1_CK1_CK1-A_CSNK1A1_ST	P30304	CDC25A	P48729	CSNK1A1	S82	G75C	75	Missense	distal	-7	no	23.603	21.895	PhosphoSitePlus;EPSD	GDSC;CCLE	20.411	Down-regulation
CK1_CK1_CK1-A_CSNK1A1_ST	P42892	ECE1	P48729	CSNK1A1	S34	L35P	35	Missense	proximal	1	no	22.472	22.362	EPSD;PhosphoSitePlus	GDSC;CCLE	20.411	Down-regulation
CK1_CK1_CK1-A_CSNK1A1_ST	P42892	ECE1	P48729	CSNK1A1	S36	L35P	35	Missense	proximal	-1	no	23.841	24.125	PhosphoSitePlus;EPSD	GDSC;CCLE	20.411	Up-regulation
CK1_CK1_CK1-A_CSNK1A1_ST	O60341	KDM1A	P48729	CSNK1A1	S166	E167*	167	Missense	proximal	1	no	20.450	19.827	EPSD	GDSC	20.411	Loss
CK1_CK1_CK1-A_CSNK1A1_ST	O14503	BHLHE40	P48729	CSNK1A1	S235	S230W	230	Missense	distal	-5	no	23.462	21.802	EPSD	GDSC	20.411	Down-regulation
CK1_CK1_CK1-A_CSNK1A1_ST	O14503	BHLHE40	P48729	CSNK1A1	S237	S230W	230	Missense	distal	-7	no	24.300	22.666	EPSD	GDSC	20.411	Down-regulation
TKL_RIPK_RIPK1_ST	Q13546	RIPK1	Q13546	RIPK1	S161	L168M	168	Missense	distal	7	no	6.228	5.955	EPSD;PhosphoSitePlus	GDSC;CCLE	2.812	Down-regulation
TKL_RIPK_RIPK1_ST	Q13546	RIPK1	Q13546	RIPK1	S166	L168M	168	Missense	proximal	2	no	6.739	6.572	EPSD;PhosphoSitePlus	GDSC;CCLE	2.812	Down-regulation
CMGC_RCK_MAK_ICK_ST	P46379	BAG6	Q9UPZ9	ICK	S16	V21E	21	Missense	distal	5	no	3.366	3.413	EPSD	GDSC	2.314	Up-regulation
CMGC_RCK_MAK_ICK_ST	P46379	BAG6	Q9UPZ9	ICK	T185	R182W	182	Missense	distal	-3	no	3.936	0.445	EPSD	GDSC	2.314	Loss
CMGC_RCK_MAK_ICK_ST	P46379	BAG6	Q9UPZ9	ICK	T185	T178S	178	Missense	distal	-7	no	3.936	3.858	EPSD	GDSC;CCLE	2.314	Down-regulation
CMGC_RCK_MAK_ICK_ST	P46379	BAG6	Q9UPZ9	ICK	S722	E724K	724	Missense	proximal	2	no	4.079	4.072	EPSD	GDSC;CCLE	2.314	Down-regulation
CMGC_RCK_MAK_ICK_ST	P46379	BAG6	Q9UPZ9	ICK	S1039	P1034S	1034	Missense	distal	-5	no	2.736	2.601	EPSD	GDSC;CCLE	2.314	Down-regulation
CMGC_RCK_MAK_ICK_ST	P46379	BAG6	Q9UPZ9	ICK	T1080	A1074V	1074	Missense	distal	-6	no	11.305	11.279	PhosphoSitePlus	GDSC;CCLE	2.314	Down-regulation
CMGC_RCK_MAK_ICK_ST	Q8N122	RPTOR	Q9UPZ9	ICK	T699	L694F	694	Missense	distal	-5	no	4.331	4.218	EPSD	GDSC;CCLE	2.314	Down-regulation
CMGC_RCK_MAK_ICK_ST	Q8N122	RPTOR	Q9UPZ9	ICK	T714	R716I	716	Missense	proximal	2	no	3.343	3.344	EPSD	GDSC;CCLE	2.314	Up-regulation
CMGC_RCK_MAK_ICK_ST	Q8N122	RPTOR	Q9UPZ9	ICK	T714	R718H	718	Missense	distal	4	no	3.343	3.380	EPSD	GDSC;CCLE	2.314	Up-regulation
CMGC_RCK_MAK_ICK_ST	Q8N122	RPTOR	Q9UPZ9	ICK	S719	R716I	716	Missense	distal	-3	no	4.089	0.425	EPSD	GDSC;CCLE	2.314	Loss
CMGC_RCK_MAK_ICK_ST	Q8N122	RPTOR	Q9UPZ9	ICK	S719	R718H	718	Missense	proximal	-1	no	4.089	4.355	EPSD	GDSC;CCLE	2.314	Up-regulation
CMGC_RCK_MAK_ICK_ST	Q8N122	RPTOR	Q9UPZ9	ICK	S721	R716I	716	Missense	distal	-5	no	3.395	3.249	EPSD	GDSC;CCLE	2.314	Down-regulation
CMGC_RCK_MAK_ICK_ST	Q8N122	RPTOR	Q9UPZ9	ICK	S721	R718H	718	Missense	distal	-3	no	3.395	-0.267	EPSD	GDSC;CCLE	2.314	Loss
CMGC_RCK_MAK_ICK_ST	Q8N122	RPTOR	Q9UPZ9	ICK	S791	S798P	798	Missense	distal	7	no	4.211	4.466	EPSD	GDSC	2.314	Up-regulation
CMGC_RCK_MAK_ICK_ST	Q8N122	RPTOR	Q9UPZ9	ICK	S792	S798P	798	Missense	distal	6	no	2.566	2.511	EPSD	GDSC	2.314	Down-regulation
CMGC_RCK_MAK_ICK_ST	Q8N122	RPTOR	Q9UPZ9	ICK	S881	S881P	881	Missense	central	0	yes	3.920	0.000	EPSD	GDSC;CCLE	2.314	Loss
CMGC_RCK_MAK_ICK_ST	Q8N122	RPTOR	Q9UPZ9	ICK	T883	S881P	881	Missense	proximal	-2	no	-0.413	2.575	EPSD	GDSC;CCLE	2.314	Gain
CMGC_RCK_MAK_ICK_ST	Q8N122	RPTOR	Q9UPZ9	ICK	S920	Y916H	916	Missense	distal	-4	no	2.681	2.682	EPSD	GDSC;CCLE	2.314	Up-regulation
STE_STE20_YSK_STK24_ST	Q9Y6E0	STK24	Q9Y6E0	STK24	S373	Q374*	374	Missense	proximal	1	no	3.411	3.381	EPSD	GDSC	2.432	Down-regulation
STE_STE20_YSK_STK24_ST	Q9Y2H1	STK38L	Q9Y6E0	STK24	T8	T9A	9	Missense	proximal	1	no	3.132	3.128	EPSD	GDSC;CCLE	2.432	Down-regulation
STE_STE20_YSK_STK24_ST	Q7L7X3	TAOK1	Q9Y6E0	STK24	S60	S60C	60	Missense	central	0	yes	3.171	0.000	EPSD	GDSC;CCLE	2.432	Loss
STE_STE20_YSK_STK24_ST	Q7L7X3	TAOK1	Q9Y6E0	STK24	S66	S60C	60	Missense	distal	-6	no	3.265	3.276	EPSD	GDSC;CCLE	2.432	Up-regulation
STE_STE20_YSK_STK24_ST	Q7L7X3	TAOK1	Q9Y6E0	STK24	S575	L570V	570	Missense	distal	-5	no	3.421	3.392	EPSD	GDSC;CCLE	2.432	Down-regulation
STE_STE20_YSK_STK24_ST	Q7L7X3	TAOK1	Q9Y6E0	STK24	S717	L715S	715	Missense	proximal	-2	no	3.033	3.026	EPSD	GDSC;CCLE	2.432	Down-regulation
CMGC_DYRK_DYRK2_DYRK2_ST	Q13541	EIF4EBP1	Q92630	DYRK2	S65	P66T	66	Missense	proximal	1	no	82.988	60.913	PhosphoSitePlus;EPSD	GDSC	45.963	Down-regulation
CMGC_DYRK_DYRK2_DYRK2_ST	Q13541	EIF4EBP1	Q92630	DYRK2	T68	P66T	66	Missense	proximal	-2	no	47.168	42.014	EPSD	GDSC	45.963	Loss
CMGC_DYRK_DYRK2_DYRK2_ST	Q13541	EIF4EBP1	Q92630	DYRK2	T70	P66T	66	Missense	distal	-4	no	56.720	53.449	EPSD	GDSC	45.963	Down-regulation
CMGC_DYRK_DYRK2_DYRK2_ST	Q13541	EIF4EBP1	Q92630	DYRK2	S101	G108S	108	Missense	distal	7	no	90.431	90.239	EPSD;PhosphoSitePlus	GDSC;CCLE	45.963	Down-regulation
CMGC_DYRK_DYRK2_DYRK2_ST	Q9Y2V2	CARHSP1	Q92630	DYRK2	T54	A53E	53	Missense	proximal	-1	no	48.708	49.595	EPSD	GDSC	45.963	Up-regulation
CMGC_DYRK_DYRK2_DYRK2_ST	O43602	DCX	Q92630	DYRK2	T289	S287T	287	Missense	proximal	-2	no	59.635	57.169	EPSD	GDSC	45.963	Down-regulation
CMGC_DYRK_DYRK2_DYRK2_ST	O75449	KATNA1	Q92630	DYRK2	T133	R129H	129	Missense	distal	-4	no	72.220	64.786	EPSD;PhosphoSitePlus	GDSC;CCLE	45.963	Down-regulation
CMGC_DYRK_DYRK2_DYRK2_ST	O75449	KATNA1	Q92630	DYRK2	T133	V134I	134	Missense	proximal	1	no	72.220	35.936	EPSD;PhosphoSitePlus	GDSC;CCLE	45.963	Loss
CMGC_DYRK_DYRK2_DYRK2_ST	O75449	KATNA1	Q92630	DYRK2	T441	R446Q	446	Missense	distal	5	no	47.492	46.705	EPSD	GDSC;CCLE	45.963	Down-regulation
CMGC_DYRK_DYRK2_DYRK2_ST	P04637	TP53	Q92630	DYRK2	S33	Q38*	38	Missense	distal	5	no	50.772	48.203	EPSD	GDSC	45.963	Down-regulation
CMGC_DYRK_DYRK2_DYRK2_ST	P04637	TP53	Q92630	DYRK2	T81	A74S	74	Missense	distal	-7	no	57.238	57.353	EPSD	GDSC;CCLE	45.963	Up-regulation
CMGC_DYRK_DYRK2_DYRK2_ST	P04637	TP53	Q92630	DYRK2	T150	Q144*	144	Missense	distal	-6	no	53.573	54.132	EPSD	GDSC	45.963	Up-regulation
CMGC_DYRK_DYRK2_DYRK2_ST	P04637	TP53	Q92630	DYRK2	T150	W146*	146	Missense	distal	-4	no	53.573	50.576	EPSD	GDSC	45.963	Down-regulation
CMGC_DYRK_DYRK2_DYRK2_ST	P04637	TP53	Q92630	DYRK2	S215	R213*	213	Missense	proximal	-2	no	56.176	36.014	EPSD	GDSC	45.963	Loss
CMGC_DYRK_DYRK2_DYRK2_ST	P04637	TP53	Q92630	DYRK2	S215	R209*	209	Missense	distal	-6	no	56.176	56.573	EPSD	GDSC	45.963	Up-regulation
CMGC_DYRK_DYRK2_DYRK2_ST	P04637	TP53	Q92630	DYRK2	S313	R306*	306	Missense	distal	-7	no	47.453	46.095	EPSD	GDSC	45.963	Down-regulation
CMGC_DYRK_DYRK2_DYRK2_ST	P04637	TP53	Q92630	DYRK2	S313	Q317*	317	Missense	distal	4	no	47.453	47.172	EPSD	GDSC	45.963	Down-regulation
CMGC_DYRK_DYRK2_DYRK2_ST	P04637	TP53	Q92630	DYRK2	S313	K319*	319	Missense	distal	6	no	47.453	46.761	EPSD	GDSC	45.963	Down-regulation
CMGC_DYRK_DYRK2_DYRK2_ST	P04637	TP53	Q92630	DYRK2	S315	Q317*	317	Missense	proximal	2	no	59.350	58.012	EPSD	GDSC	45.963	Down-regulation
CMGC_DYRK_DYRK2_DYRK2_ST	P04637	TP53	Q92630	DYRK2	S315	K319*	319	Missense	distal	4	no	59.350	59.068	EPSD	GDSC	45.963	Down-regulation
CMGC_DYRK_DYRK2_DYRK2_ST	P04637	TP53	Q92630	DYRK2	S366	G360V	360	Missense	distal	-6	no	53.248	53.016	EPSD	GDSC;CCLE	45.963	Down-regulation
CMGC_DYRK_DYRK2_DYRK2_ST	Q14195	DPYSL3	Q92630	DYRK2	S363	I365F	365	Missense	proximal	2	no	61.818	61.029	EPSD	GDSC;CCLE	45.963	Down-regulation
CMGC_DYRK_DYRK2_DYRK2_ST	Q14195	DPYSL3	Q92630	DYRK2	T567	S568Y	568	Missense	proximal	1	no	59.421	-9.775	EPSD	GDSC;CCLE	45.963	Loss
CMGC_DYRK_DYRK2_DYRK2_ST	Q16555	DPYSL2	Q92630	DYRK2	S416	S421F	421	Missense	distal	5	no	49.689	47.740	EPSD	GDSC;CCLE	45.963	Down-regulation
CMGC_DYRK_DYRK2_DYRK2_ST	Q16555	DPYSL2	Q92630	DYRK2	S522	Q526*	526	Missense	distal	4	no	81.328	81.047	PhosphoSitePlus	GDSC	45.963	Down-regulation
CMGC_DYRK_DYRK2_DYRK2_ST	Q16555	DPYSL2	Q92630	DYRK2	S537	P530A	530	Missense	distal	-7	no	47.827	46.487	EPSD	GDSC;CCLE	45.963	Down-regulation
CMGC_DYRK_DYRK2_DYRK2_ST	Q16555	DPYSL2	Q92630	DYRK2	T555	A560V	560	Missense	distal	5	no	49.385	48.771	EPSD	GDSC	45.963	Down-regulation
CMGC_DYRK_DYRK2_DYRK2_ST	P10636	MAPT	Q92630	DYRK2	S46	Q49H	49	Missense	distal	3	no	55.663	53.669	EPSD	GDSC	45.963	Down-regulation
CMGC_DYRK_DYRK2_DYRK2_ST	P10636	MAPT	Q92630	DYRK2	S46	A41V	41	Missense	distal	-5	no	55.663	55.716	EPSD	GDSC;CCLE	45.963	Up-regulation
CMGC_DYRK_DYRK2_DYRK2_ST	P10636	MAPT	Q92630	DYRK2	T50	Q49H	49	Missense	proximal	-1	no	59.765	62.728	EPSD	GDSC	45.963	Up-regulation
CMGC_DYRK_DYRK2_DYRK2_ST	P10636	MAPT	Q92630	DYRK2	S214	V218G	218	Missense	distal	4	no	65.937	65.809	EPSD	GDSC	45.963	Down-regulation
CMGC_DYRK_DYRK2_DYRK2_ST	P10636	MAPT	Q92630	DYRK2	T470	A475V	475	Missense	distal	5	no	54.038	53.425	EPSD	GDSC;CCLE	45.963	Down-regulation
CMGC_DYRK_DYRK2_DYRK2_ST	P10636	MAPT	Q92630	DYRK2	S637	V635I	635	Missense	proximal	-2	no	55.913	49.908	EPSD	GDSC	45.963	Down-regulation
CMGC_DYRK_DYRK2_DYRK2_ST	P10636	MAPT	Q92630	DYRK2	S739	S739C	739	Missense	central	0	yes	67.423	0.000	EPSD	GDSC	45.963	Loss
Other_BUB_BUB1_ST	O43683	BUB1	O43683	BUB1	S375	S375F	375	Missense	central	0	yes	0.000	0.000	EPSD	GDSC;CCLE	0.000	Loss
AGC_PKC_PKCh_PRKCE_ST	Q16625	OCLN	Q02156	PRKCE	S302	V308L	308	Missense	distal	6	no	14.168	14.062	EPSD	GDSC	13.948	Down-regulation
AGC_PKC_PKCh_PRKCE_ST	Q16625	OCLN	Q02156	PRKCE	T403	D401N	401	Missense	proximal	-2	no	15.391	16.266	EPSD;PhosphoSitePlus	GDSC;CCLE	13.948	Up-regulation
AGC_PKC_PKCh_PRKCE_ST	Q16625	OCLN	Q02156	PRKCE	T403	Y402C	402	Missense	proximal	-1	no	15.391	14.888	EPSD;PhosphoSitePlus	GDSC;CCLE	13.948	Down-regulation
AGC_PKC_PKCh_PRKCE_ST	Q16625	OCLN	Q02156	PRKCE	T404	Y402C	402	Missense	proximal	-2	no	13.879	14.743	PhosphoSitePlus;EPSD	GDSC;CCLE	13.948	Gain
AGC_PKC_PKCh_PRKCE_ST	P11362	FGFR1	Q02156	PRKCE	S790	E792K	792	Missense	proximal	2	no	11.100	17.767	EPSD	GDSC;CCLE	13.948	Gain
AGC_PKC_PKCh_PRKCE_ST	P10636	MAPT	Q02156	PRKCE	S171	D177V	177	Missense	distal	6	no	13.651	14.107	EPSD	GDSC	13.948	Gain
AGC_PKC_PKCh_PRKCE_ST	P10636	MAPT	Q02156	PRKCE	S214	V218G	218	Missense	distal	4	no	15.548	16.067	EPSD	GDSC	13.948	Up-regulation
AGC_PKC_PKCh_PRKCE_ST	P10636	MAPT	Q02156	PRKCE	S341	P340L	340	Missense	proximal	-1	no	20.741	20.805	EPSD	GDSC;CCLE	13.948	Up-regulation
AGC_PKC_PKCh_PRKCE_ST	P10636	MAPT	Q02156	PRKCE	S341	G339S	339	Missense	proximal	-2	no	20.741	20.520	EPSD	GDSC;CCLE	13.948	Down-regulation
AGC_PKC_PKCh_PRKCE_ST	P10636	MAPT	Q02156	PRKCE	S355	E353D	353	Missense	proximal	-2	no	15.706	15.206	EPSD	GDSC;CCLE	13.948	Down-regulation
AGC_PKC_PKCh_PRKCE_ST	P10636	MAPT	Q02156	PRKCE	S637	V635I	635	Missense	proximal	-2	no	14.905	14.016	EPSD	GDSC	13.948	Down-regulation
AGC_PKC_PKCh_PRKCE_ST	P10636	MAPT	Q02156	PRKCE	S641	V635I	635	Missense	distal	-6	no	16.858	16.838	EPSD	GDSC	13.948	Down-regulation
AGC_PKC_PKCh_PRKCE_ST	P10636	MAPT	Q02156	PRKCE	S733	S739C	739	Missense	distal	6	no	15.481	15.445	EPSD	GDSC	13.948	Down-regulation
AGC_PKC_PKCh_PRKCE_ST	O75689	ADAP1	Q02156	PRKCE	S204	I208M	208	Missense	distal	4	no	18.789	18.883	EPSD	GDSC;CCLE	13.948	Up-regulation
AGC_PKC_PKCh_PRKCE_ST	Q86XR7	TICAM2	Q02156	PRKCE	S16	N9H	9	Missense	distal	-7	no	14.368	14.149	PhosphoSitePlus	GDSC	13.948	Down-regulation
AGC_PKC_PKCh_PRKCE_ST	Q14145	KEAP1	Q02156	PRKCE	S599	T598I	598	Missense	proximal	-1	no	31.933	31.684	EPSD;PhosphoSitePlus	GDSC;CCLE	13.948	Down-regulation
AGC_PKC_PKCh_PRKCE_ST	Q14145	KEAP1	Q02156	PRKCE	S602	T598I	598	Missense	distal	-4	no	19.003	19.171	PhosphoSitePlus;EPSD	GDSC;CCLE	13.948	Up-regulation
AGC_PKC_PKCh_PRKCE_ST	Q92934	BAD	Q02156	PRKCE	S124	L129F	129	Missense	distal	5	no	21.399	21.505	EPSD	GDSC	13.948	Up-regulation
AGC_PKC_PKCh_PRKCE_ST	P78536	ADAM17	Q02156	PRKCE	T87	Q92K	92	Missense	distal	5	no	15.090	15.093	EPSD	GDSC;CCLE	13.948	Up-regulation
AGC_PKC_PKCh_PRKCE_ST	P78536	ADAM17	Q02156	PRKCE	T761	Q763H	763	Missense	proximal	2	no	14.126	12.387	EPSD	GDSC;CCLE	13.948	Loss
AGC_PKC_PKCh_PRKCE_ST	P78536	ADAM17	Q02156	PRKCE	T761	Q757R	757	Missense	distal	-4	no	14.126	13.983	EPSD	GDSC;CCLE	13.948	Down-regulation
AGC_PKC_PKCh_PRKCE_ST	P78536	ADAM17	Q02156	PRKCE	S819	K820R	820	Missense	proximal	1	no	20.230	19.240	EPSD	GDSC;CCLE	13.948	Down-regulation
AGC_PKC_PKCh_PRKCE_ST	P04899	GNAI2	Q02156	PRKCE	S44	G45R	45	Missense	proximal	1	no	21.352	21.154	EPSD;PhosphoSitePlus	GDSC;CCLE	13.948	Down-regulation
AGC_PKC_PKCh_PRKCE_ST	P04899	GNAI2	Q02156	PRKCE	S207	Q205R	205	Missense	proximal	-2	no	13.881	14.852	EPSD	GDSC;CCLE	13.948	Gain
AGC_PKC_PKCh_PRKCE_ST	P43629	KIR3DL1	Q02156	PRKCE	S415	P422S	422	Missense	distal	7	no	17.613	18.234	PhosphoSitePlus	GDSC;CCLE	13.948	Up-regulation
AGC_PKC_PKCh_PRKCE_ST	P43629	KIR3DL1	Q02156	PRKCE	T420	P422S	422	Missense	proximal	2	no	14.228	13.574	EPSD	GDSC;CCLE	13.948	Loss
AGC_PKC_PKCh_PRKCE_ST	Q9UBS0	RPS6KB2	Q02156	PRKCE	S416	R419Q	419	Missense	distal	3	no	15.168	15.003	EPSD	GDSC;CCLE	13.948	Down-regulation
AGC_PKC_PKCh_PRKCE_ST	Q9UBS0	RPS6KB2	Q02156	PRKCE	S468	R465C	465	Missense	distal	-3	no	18.613	10.523	EPSD	GDSC;CCLE	13.948	Loss
AGC_PKC_PKCh_PRKCE_ST	Q9UBS0	RPS6KB2	Q02156	PRKCE	T470	R465C	465	Missense	distal	-5	no	20.520	20.542	EPSD	GDSC;CCLE	13.948	Up-regulation
AGC_PKC_PKCh_PRKCE_ST	P05783	KRT18	Q02156	PRKCE	S127	H128L	128	Missense	proximal	1	no	12.619	14.986	EPSD	GDSC	13.948	Gain
AGC_PKC_PKCh_PRKCE_ST	Q02156	PRKCE	Q02156	PRKCE	T228	D230V	230	Missense	proximal	2	no	13.654	14.273	EPSD	GDSC;CCLE	13.948	Gain
AGC_PKC_PKCh_PRKCE_ST	Q02156	PRKCE	Q02156	PRKCE	S234	D230V	230	Missense	distal	-4	no	18.167	18.222	EPSD;PhosphoSitePlus	GDSC;CCLE	13.948	Up-regulation
AGC_PKC_PKCh_PRKCE_ST	Q02156	PRKCE	Q02156	PRKCE	S380	R377Q	377	Missense	distal	-3	no	14.241	8.675	EPSD	GDSC	13.948	Loss
AGC_PKC_PKCh_PRKCE_ST	Q02156	PRKCE	Q02156	PRKCE	S729	G732C	732	Missense	distal	3	no	18.653	18.211	EPSD;PhosphoSitePlus	GDSC;CCLE	13.948	Down-regulation
AGC_PKC_PKCh_PRKCE_ST	O94925	GLS	Q02156	PRKCE	S314	R307L	307	Missense	distal	-7	no	16.352	16.031	PhosphoSitePlus	GDSC;CCLE	13.948	Down-regulation
AGC_PKC_PKCh_PRKCE_ST	P46940	IQGAP1	Q02156	PRKCE	S91	F84L	84	Missense	distal	-7	no	18.534	18.661	EPSD	GDSC;CCLE	13.948	Up-regulation
AGC_PKC_PKCh_PRKCE_ST	P46940	IQGAP1	Q02156	PRKCE	S360	D353E	353	Missense	distal	-7	no	17.160	17.188	EPSD	GDSC	13.948	Up-regulation
AGC_PKC_PKCh_PRKCE_ST	P46940	IQGAP1	Q02156	PRKCE	S962	R966*	966	Missense	distal	4	no	14.637	13.637	EPSD	GDSC	13.948	Loss
AGC_PKC_PKCh_PRKCE_ST	P46940	IQGAP1	Q02156	PRKCE	S1237	L1232F	1232	Missense	distal	-5	no	14.075	14.069	EPSD	GDSC	13.948	Down-regulation
AGC_PKC_PKCh_PRKCE_ST	P05091	ALDH2	Q02156	PRKCE	T283	G287A	287	Missense	distal	4	no	14.529	12.336	EPSD	GDSC;CCLE	13.948	Loss
AGC_PKC_PKCh_PRKCE_ST	Q15139	PRKD1	Q02156	PRKCE	S401	N403S	403	Missense	proximal	2	no	13.976	13.313	EPSD	GDSC	13.948	Loss
AGC_PKC_PKCh_PRKCE_ST	Q15139	PRKD1	Q02156	PRKCE	S401	R408M	408	Missense	distal	7	no	13.976	14.088	EPSD	GDSC;CCLE	13.948	Up-regulation
AGC_PKC_PKCh_PRKCE_ST	Q15139	PRKD1	Q02156	PRKCE	S412	R408M	408	Missense	distal	-4	no	14.595	14.834	EPSD	GDSC;CCLE	13.948	Up-regulation
AGC_PKC_PKCh_PRKCE_ST	Q15139	PRKD1	Q02156	PRKCE	S829	K826E	826	Missense	distal	-3	no	18.738	11.612	EPSD	GDSC;CCLE	13.948	Loss
AGC_PKC_PKCh_PRKCE_ST	Q15139	PRKD1	Q02156	PRKCE	S910	G906D	906	Missense	distal	-4	no	14.354	14.181	EPSD	GDSC;CCLE	13.948	Down-regulation
AGC_PKC_PKCh_PRKCE_ST	Q15139	PRKD1	Q02156	PRKCE	S910	G906S	906	Missense	distal	-4	no	14.354	14.357	EPSD	GDSC	13.948	Up-regulation
AGC_PKC_PKCh_PRKCE_ST	Q15139	PRKD1	Q02156	PRKCE	S910	K903E	903	Missense	distal	-7	no	14.354	14.456	EPSD	GDSC;CCLE	13.948	Up-regulation
AGC_PKC_PKCh_PRKCE_ST	P00533	EGFR	Q02156	PRKCE	S227	N234D	234	Missense	distal	7	no	14.792	15.472	EPSD	GDSC;CCLE	13.948	Up-regulation
AGC_PKC_PKCh_PRKCE_ST	P00533	EGFR	Q02156	PRKCE	S752	A750E	750	Missense	proximal	-2	no	14.001	14.238	EPSD	GDSC	13.948	Up-regulation
AGC_PKC_PKCh_PRKCE_ST	P00533	EGFR	Q02156	PRKCE	S1064	R1068*	1068	Missense	distal	4	no	14.638	13.638	EPSD	GDSC	13.948	Loss
AGC_PKC_PKCh_PRKCE_ST	Q5JXC2	MIIP	Q02156	PRKCE	S113	G107S	107	Missense	distal	-6	no	16.008	15.991	EPSD	GDSC;CCLE	13.948	Down-regulation
AGC_PKC_PKCh_PRKCE_ST	P62491	RAB11A	Q02156	PRKCE	S177	K179*	179	Missense	proximal	2	no	19.438	3.031	PhosphoSitePlus	GDSC	13.948	Loss
AGC_PKC_PKCh_PRKCE_ST	P62491	RAB11A	Q02156	PRKCE	S177	V176A	176	Missense	proximal	-1	no	19.438	19.635	PhosphoSitePlus	GDSC;CCLE	13.948	Up-regulation
AGC_PKC_PKCh_PRKCE_ST	P20339	RAB5A	Q02156	PRKCE	S193	R197T	197	Missense	distal	4	no	14.772	13.568	EPSD	GDSC	13.948	Loss
AGC_PKC_PKCh_PRKCE_ST	P05556	ITGB1	Q02156	PRKCE	S61	G57E	57	Missense	distal	-4	no	16.146	15.951	EPSD	GDSC;CCLE	13.948	Down-regulation
AGC_PKC_PKCh_PRKCE_ST	P05556	ITGB1	Q02156	PRKCE	S327	I334V	334	Missense	distal	7	no	14.061	13.567	EPSD	GDSC;CCLE	13.948	Loss
AGC_PKC_PKCh_PRKCE_ST	Q96GD4	AURKB	Q02156	PRKCE	S331	P325S	325	Missense	distal	-6	no	27.336	27.346	EPSD	GDSC	13.948	Up-regulation
AGC_PKC_PKCh_PRKCE_ST	P28329	CHAT	Q02156	PRKCE	S244	D250G	250	Missense	distal	6	no	16.939	17.194	EPSD	GDSC;CCLE	13.948	Up-regulation
AGC_PKC_PKCh_PRKCE_ST	P28329	CHAT	Q02156	PRKCE	S473	P478L	478	Missense	distal	5	no	15.176	15.053	EPSD	GDSC;CCLE	13.948	Down-regulation
AGC_PKC_PKCh_PRKCE_ST	P28329	CHAT	Q02156	PRKCE	S473	P480S	480	Missense	distal	7	no	15.176	15.797	EPSD	GDSC;CCLE	13.948	Up-regulation
AGC_PKC_PKCh_PRKCE_ST	P28329	CHAT	Q02156	PRKCE	S473	P480L	480	Missense	distal	7	no	15.176	15.339	EPSD	GDSC;CCLE	13.948	Up-regulation
AGC_PKC_PKCh_PRKCE_ST	P28329	CHAT	Q02156	PRKCE	S558	E555D	555	Missense	distal	-3	no	17.756	18.475	EPSD	GDSC;CCLE	13.948	Up-regulation
AGC_PKC_PKCh_PRKCE_ST	P28329	CHAT	Q02156	PRKCE	S594	A590D	590	Missense	distal	-4	no	16.427	16.273	EPSD	GDSC;CCLE	13.948	Down-regulation
AGC_PKC_PKCh_PRKCE_ST	P17302	GJA1	Q02156	PRKCE	S296	G291D	291	Missense	distal	-5	no	17.123	17.140	EPSD	GDSC;CCLE	13.948	Up-regulation
AGC_PKC_PKCh_PRKCE_ST	P17302	GJA1	Q02156	PRKCE	S296	R299C	299	Missense	distal	3	no	17.123	16.715	EPSD	GDSC;CCLE	13.948	Down-regulation
AGC_PKC_PKCh_PRKCE_ST	P17302	GJA1	Q02156	PRKCE	S296	V289G	289	Missense	distal	-7	no	17.123	17.288	EPSD	GDSC;CCLE	13.948	Up-regulation
AGC_PKC_PKCh_PRKCE_ST	P17302	GJA1	Q02156	PRKCE	S296	D292G	292	Missense	distal	-4	no	17.123	17.296	EPSD	GDSC;CCLE	13.948	Up-regulation
AGC_PKC_PKCh_PRKCE_ST	Q9BZL6	PRKD2	Q02156	PRKCE	S239	S245T	245	Missense	distal	6	no	14.126	14.182	EPSD	GDSC;CCLE	13.948	Up-regulation
AGC_PKC_PKCh_PRKCE_ST	Q9BZL6	PRKD2	Q02156	PRKCE	S706	R708C	708	Missense	proximal	2	no	20.395	13.971	EPSD;PhosphoSitePlus	GDSC;CCLE	13.948	Down-regulation
AGC_PKC_PKCh_PRKCE_ST	Q9BZL6	PRKD2	Q02156	PRKCE	S710	R708C	708	Missense	proximal	-2	no	17.665	16.161	EPSD;PhosphoSitePlus	GDSC;CCLE	13.948	Down-regulation
AGC_PKC_PKCh_PRKCE_ST	O14920	IKBKB	Q02156	PRKCE	S507	S507*	507	Missense	central	0	yes	14.810	0.000	EPSD	GDSC	13.948	Loss
AGC_PKC_PKCh_PRKCE_ST	O14920	IKBKB	Q02156	PRKCE	S756	A755V	755	Missense	proximal	-1	no	14.378	14.181	EPSD	GDSC;CCLE	13.948	Down-regulation
AGC_PKC_PKCh_PRKCE_ST	P15336	ATF2	Q02156	PRKCE	S340	R342H	342	Missense	proximal	2	no	17.489	10.517	EPSD	GDSC;CCLE	13.948	Loss
AGC_PKC_PKCh_PRKCE_ST	O60716	CTNND1	Q02156	PRKCE	S268	G267W	267	Missense	proximal	-1	no	15.243	14.055	PhosphoSitePlus	GDSC;CCLE	13.948	Down-regulation
AGC_PKC_PKCh_PRKCE_ST	O60716	CTNND1	Q02156	PRKCE	S320	M324I	324	Missense	distal	4	no	15.343	15.249	EPSD	GDSC;CCLE	13.948	Down-regulation
AGC_PKC_PKCh_PRKCE_ST	O60716	CTNND1	Q02156	PRKCE	S484	W477*	477	Missense	distal	-7	no	18.581	18.696	EPSD	GDSC	13.948	Up-regulation
AGC_PKC_PKCh_PRKCE_ST	O60716	CTNND1	Q02156	PRKCE	S731	A738V	738	Missense	distal	7	no	16.625	15.044	EPSD	GDSC;CCLE	13.948	Down-regulation
STE_STE20_MST_STK3_ST	P17252	PRKCA	Q13188	STK3	S258	M256I	256	Missense	proximal	-2	no	57.560	57.192	EPSD	GDSC;CCLE	55.172	Down-regulation
STE_STE20_MST_STK3_ST	Q7L9L4	MOB1B	Q13188	STK3	T12	N18S	18	Missense	distal	6	no	96.089	100.175	EPSD;PhosphoSitePlus	GDSC;CCLE	55.172	Up-regulation
STE_STE20_MST_STK3_ST	Q7L9L4	MOB1B	Q13188	STK3	T35	G37D	37	Missense	proximal	2	no	100.261	100.297	EPSD;PhosphoSitePlus	GDSC;CCLE	55.172	Up-regulation
STE_STE20_MST_STK3_ST	Q9H4B6	SAV1	Q13188	STK3	S269	R272W	272	Missense	distal	3	no	93.324	95.159	EPSD;PhosphoSitePlus	GDSC;CCLE	55.172	Up-regulation
STE_STE20_MST_STK3_ST	Q9H4B6	SAV1	Q13188	STK3	S269	Y273*	273	Missense	distal	4	no	93.324	95.470	EPSD;PhosphoSitePlus	GDSC	55.172	Up-regulation
STE_STE20_MST_STK3_ST	P51955	NEK2	Q13188	STK3	S356	S356N	356	Missense	central	0	yes	91.920	0.000	EPSD;PhosphoSitePlus	GDSC;CCLE	55.172	Loss
STE_STE20_MST_STK3_ST	O95835	LATS1	Q13188	STK3	S575	E574*	574	Missense	proximal	-1	no	54.722	59.820	EPSD	GDSC	55.172	Gain
STE_STE20_MST_STK3_ST	O95835	LATS1	Q13188	STK3	T1012	K1005*	1005	Missense	distal	-7	no	96.824	99.000	EPSD;PhosphoSitePlus	GDSC	55.172	Up-regulation
STE_STE20_MST_STK3_ST	Q13188	STK3	Q13188	STK3	S333	E332*	332	Missense	proximal	-1	no	58.060	63.159	EPSD	GDSC	55.172	Up-regulation
STE_STE20_MST_STK3_ST	Q13188	STK3	Q13188	STK3	T364	D361N	361	Missense	distal	-3	no	63.595	65.273	EPSD	GDSC;CCLE	55.172	Up-regulation
STE_STE20_MST_STK3_ST	P46937	YAP1	Q13188	STK3	T361	Q357P	357	Missense	distal	-4	no	59.163	59.134	EPSD	GDSC	55.172	Down-regulation
STE_STE20_MST_STK3_ST	P46937	YAP1	Q13188	STK3	T361	E356D	356	Missense	distal	-5	no	59.163	47.664	EPSD	GDSC;CCLE	55.172	Loss
Atypical_PIKK_ATR_ATR_ST	P25205	MCM3	Q13535	ATR	T542	K547Q	547	Missense	distal	5	no	11.598	11.596	EPSD	GDSC;CCLE	10.658	Down-regulation
Atypical_PIKK_ATR_ATR_ST	P25205	MCM3	Q13535	ATR	T713	V720A	720	Missense	distal	7	no	12.026	11.886	EPSD	GDSC	10.658	Down-regulation
Atypical_PIKK_ATR_ATR_ST	P25205	MCM3	Q13535	ATR	S728	T725M	725	Missense	distal	-3	no	21.461	21.198	EPSD	GDSC;CCLE	10.658	Down-regulation
Atypical_PIKK_ATR_ATR_ST	P25205	MCM3	Q13535	ATR	S734	E741K	741	Missense	distal	7	no	13.388	13.537	EPSD	GDSC;CCLE	10.658	Up-regulation
Atypical_PIKK_ATR_ATR_ST	O60934	NBN	Q13535	ATR	S58	T60K	60	Missense	proximal	2	no	11.537	12.047	EPSD	GDSC;CCLE	10.658	Up-regulation
Atypical_PIKK_ATR_ATR_ST	O60934	NBN	Q13535	ATR	T60	T60K	60	Missense	central	0	yes	11.017	0.000	EPSD	GDSC;CCLE	10.658	Loss
Atypical_PIKK_ATR_ATR_ST	O60934	NBN	Q13535	ATR	S343	E350G	350	Missense	distal	7	no	16.611	16.616	PhosphoSitePlus;EPSD	GDSC;CCLE	10.658	Up-regulation
Atypical_PIKK_ATR_ATR_ST	O60934	NBN	Q13535	ATR	S397	F393L	393	Missense	distal	-4	no	13.700	13.108	EPSD	GDSC;CCLE	10.658	Down-regulation
Atypical_PIKK_ATR_ATR_ST	O60934	NBN	Q13535	ATR	S415	L421S	421	Missense	distal	6	no	13.308	13.533	EPSD	GDSC	10.658	Up-regulation
Atypical_PIKK_ATR_ATR_ST	O60934	NBN	Q13535	ATR	S415	N414S	414	Missense	proximal	-1	no	13.308	12.831	EPSD	GDSC;CCLE	10.658	Down-regulation
Atypical_PIKK_ATR_ATR_ST	O60934	NBN	Q13535	ATR	S415	K408E	408	Missense	distal	-7	no	13.308	13.325	EPSD	GDSC	10.658	Up-regulation
Atypical_PIKK_ATR_ATR_ST	O60934	NBN	Q13535	ATR	S447	Q448*	448	Missense	proximal	1	no	12.757	9.444	EPSD	GDSC	10.658	Loss
Atypical_PIKK_ATR_ATR_ST	O60934	NBN	Q13535	ATR	S447	Q448R	448	Missense	proximal	1	no	12.757	5.761	EPSD	GDSC;CCLE	10.658	Loss
Atypical_PIKK_ATR_ATR_ST	O60934	NBN	Q13535	ATR	S615	K613E	613	Missense	proximal	-2	no	17.909	17.810	EPSD;PhosphoSitePlus	GDSC;CCLE	10.658	Down-regulation
Atypical_PIKK_ATR_ATR_ST	P78527	PRKDC	Q13535	ATR	S245	V252A	252	Missense	distal	7	no	11.126	10.986	EPSD	GDSC;CCLE	10.658	Down-regulation
Atypical_PIKK_ATR_ATR_ST	P78527	PRKDC	Q13535	ATR	S922	K927E	927	Missense	distal	5	no	11.243	11.234	EPSD	GDSC;CCLE	10.658	Down-regulation
Atypical_PIKK_ATR_ATR_ST	P78527	PRKDC	Q13535	ATR	S936	M939V	939	Missense	distal	3	no	11.550	12.341	EPSD	GDSC;CCLE	10.658	Up-regulation
Atypical_PIKK_ATR_ATR_ST	P78527	PRKDC	Q13535	ATR	T946	M939V	939	Missense	distal	-7	no	13.230	13.186	EPSD	GDSC;CCLE	10.658	Down-regulation
Atypical_PIKK_ATR_ATR_ST	P78527	PRKDC	Q13535	ATR	S1470	H1476Y	1476	Missense	distal	6	no	14.194	14.020	EPSD	GDSC;CCLE	10.658	Down-regulation
Atypical_PIKK_ATR_ATR_ST	Q8IUH4	ZDHHC13	Q13535	ATR	S8	N12D	12	Missense	distal	4	no	13.628	12.938	PhosphoSitePlus	GDSC;CCLE	10.658	Down-regulation
Atypical_PIKK_ATR_ATR_ST	Q99708	RBBP8	Q13535	ATR	S10	G9E	9	Missense	proximal	-1	no	11.057	11.106	EPSD	GDSC;CCLE	10.658	Up-regulation
Atypical_PIKK_ATR_ATR_ST	Q99708	RBBP8	Q13535	ATR	T16	G9E	9	Missense	distal	-7	no	10.727	10.805	EPSD	GDSC;CCLE	10.658	Up-regulation
Atypical_PIKK_ATR_ATR_ST	Q99708	RBBP8	Q13535	ATR	S593	E597Q	597	Missense	distal	4	no	11.000	11.128	EPSD	GDSC;CCLE	10.658	Up-regulation
Atypical_PIKK_ATR_ATR_ST	Q99708	RBBP8	Q13535	ATR	T596	E597Q	597	Missense	proximal	1	no	11.187	17.107	EPSD	GDSC;CCLE	10.658	Up-regulation
Atypical_PIKK_ATR_ATR_ST	Q99708	RBBP8	Q13535	ATR	S664	I657V	657	Missense	distal	-7	no	11.369	11.430	EPSD	GDSC;CCLE	10.658	Up-regulation
Atypical_PIKK_ATR_ATR_ST	Q99708	RBBP8	Q13535	ATR	S679	K676N	676	Missense	distal	-3	no	13.465	14.624	EPSD	GDSC	10.658	Up-regulation
Atypical_PIKK_ATR_ATR_ST	Q99708	RBBP8	Q13535	ATR	S679	S679G	679	Missense	central	0	yes	13.465	0.000	EPSD	GDSC;CCLE	10.658	Loss
Atypical_PIKK_ATR_ATR_ST	Q99708	RBBP8	Q13535	ATR	S745	A741V	741	Missense	distal	-4	no	12.813	11.824	EPSD	GDSC;CCLE	10.658	Down-regulation
Atypical_PIKK_ATR_ATR_ST	Q99708	RBBP8	Q13535	ATR	S789	G783C	783	Missense	distal	-6	no	12.054	12.093	EPSD	GDSC;CCLE	10.658	Up-regulation
Atypical_PIKK_ATR_ATR_ST	Q9UPV0	CEP164	Q13535	ATR	S234	Q229R	229	Missense	distal	-5	no	11.289	11.382	EPSD	GDSC	10.658	Up-regulation
Atypical_PIKK_ATR_ATR_ST	Q9UPV0	CEP164	Q13535	ATR	S319	K318*	318	Missense	proximal	-1	no	10.968	11.763	EPSD	GDSC	10.658	Up-regulation
Atypical_PIKK_ATR_ATR_ST	Q9UPV0	CEP164	Q13535	ATR	S566	P569S	569	Missense	distal	3	no	10.902	10.966	EPSD	GDSC;CCLE	10.658	Up-regulation
Atypical_PIKK_ATR_ATR_ST	Q9UPV0	CEP164	Q13535	ATR	S566	P569L	569	Missense	distal	3	no	10.902	10.299	EPSD	GDSC;CCLE	10.658	Loss
Atypical_PIKK_ATR_ATR_ST	Q9UPV0	CEP164	Q13535	ATR	S572	P569S	569	Missense	distal	-3	no	10.740	10.464	EPSD	GDSC;CCLE	10.658	Loss
Atypical_PIKK_ATR_ATR_ST	Q9UPV0	CEP164	Q13535	ATR	S572	P569L	569	Missense	distal	-3	no	10.740	11.035	EPSD	GDSC;CCLE	10.658	Up-regulation
Atypical_PIKK_ATR_ATR_ST	Q9UPV0	CEP164	Q13535	ATR	S646	R650Q	650	Missense	distal	4	no	11.262	11.096	EPSD	GDSC;CCLE	10.658	Down-regulation
Atypical_PIKK_ATR_ATR_ST	Q9UPV0	CEP164	Q13535	ATR	S646	E641V	641	Missense	distal	-5	no	11.262	11.445	EPSD	GDSC;CCLE	10.658	Up-regulation
Atypical_PIKK_ATR_ATR_ST	Q12888	TP53BP1	Q13535	ATR	S29	E33A	33	Missense	distal	4	no	12.223	12.767	EPSD	GDSC	10.658	Up-regulation
Atypical_PIKK_ATR_ATR_ST	Q96RL1	UIMC1	Q13535	ATR	S101	A96D	96	Missense	distal	-5	no	13.164	13.236	EPSD	GDSC;CCLE	10.658	Up-regulation
Atypical_PIKK_ATR_ATR_ST	Q96RL1	UIMC1	Q13535	ATR	S168	H169Q	169	Missense	proximal	1	no	-3.344	14.174	EPSD	GDSC;CCLE	10.658	Gain
Atypical_PIKK_ATR_ATR_ST	Q96RL1	UIMC1	Q13535	ATR	S171	H169Q	169	Missense	proximal	-2	no	12.550	12.917	EPSD	GDSC;CCLE	10.658	Up-regulation
Atypical_PIKK_ATR_ATR_ST	Q96RL1	UIMC1	Q13535	ATR	S171	I170V	170	Missense	proximal	-1	no	12.550	12.298	EPSD	GDSC;CCLE	10.658	Down-regulation
Atypical_PIKK_ATR_ATR_ST	Q96RL1	UIMC1	Q13535	ATR	S171	F165C	165	Missense	distal	-6	no	12.550	12.539	EPSD	GDSC;CCLE	10.658	Down-regulation
Atypical_PIKK_ATR_ATR_ST	Q96RL1	UIMC1	Q13535	ATR	S205	V212E	212	Missense	distal	7	no	16.798	16.550	PhosphoSitePlus	GDSC;CCLE	10.658	Down-regulation
Atypical_PIKK_ATR_ATR_ST	Q96RL1	UIMC1	Q13535	ATR	S379	S380P	380	Missense	proximal	1	no	10.760	11.870	EPSD	GDSC	10.658	Up-regulation
Atypical_PIKK_ATR_ATR_ST	Q96RL1	UIMC1	Q13535	ATR	S643	S643F	643	Missense	central	0	yes	10.768	0.000	EPSD	GDSC;CCLE	10.658	Loss
Atypical_PIKK_ATR_ATR_ST	Q96RL1	UIMC1	Q13535	ATR	S644	S643F	643	Missense	proximal	-1	no	10.887	10.889	EPSD	GDSC;CCLE	10.658	Up-regulation
Atypical_PIKK_ATR_ATR_ST	Q96RL1	UIMC1	Q13535	ATR	S677	R671H	671	Missense	distal	-6	no	12.139	12.145	EPSD	GDSC	10.658	Up-regulation
Atypical_PIKK_ATR_ATR_ST	P39880	CUX1	Q13535	ATR	S868	Q869*	869	Missense	proximal	1	no	11.489	8.177	EPSD	GDSC	10.658	Loss
Atypical_PIKK_ATR_ATR_ST	P39880	CUX1	Q13535	ATR	S1100	D1094A	1094	Missense	distal	-6	no	13.302	13.347	EPSD	GDSC;CCLE	10.658	Up-regulation
Atypical_PIKK_ATR_ATR_ST	P39880	CUX1	Q13535	ATR	S1220	S1218N	1218	Missense	proximal	-2	no	12.448	13.297	EPSD	GDSC;CCLE	10.658	Up-regulation
Atypical_PIKK_ATR_ATR_ST	P39880	CUX1	Q13535	ATR	S1455	S1448F	1448	Missense	distal	-7	no	11.344	11.236	EPSD	GDSC	10.658	Down-regulation
Atypical_PIKK_ATR_ATR_ST	Q01094	E2F1	Q13535	ATR	S313	G309E	309	Missense	distal	-4	no	14.237	15.769	EPSD	GDSC;CCLE	10.658	Up-regulation
Atypical_PIKK_ATR_ATR_ST	Q01094	E2F1	Q13535	ATR	S347	L351V	351	Missense	distal	4	no	12.827	12.753	EPSD	GDSC;CCLE	10.658	Down-regulation
Atypical_PIKK_ATR_ATR_ST	Q01094	E2F1	Q13535	ATR	S347	S349Y	349	Missense	proximal	2	no	12.827	10.547	EPSD	GDSC;CCLE	10.658	Loss
Atypical_PIKK_ATR_ATR_ST	Q01094	E2F1	Q13535	ATR	S349	L351V	351	Missense	proximal	2	no	10.790	12.393	EPSD	GDSC;CCLE	10.658	Up-regulation
Atypical_PIKK_ATR_ATR_ST	Q01094	E2F1	Q13535	ATR	S349	S349Y	349	Missense	central	0	yes	10.790	0.000	EPSD	GDSC;CCLE	10.658	Loss
Atypical_PIKK_ATR_ATR_ST	Q01094	E2F1	Q13535	ATR	S352	P357Q	357	Missense	distal	5	no	10.785	10.775	EPSD	GDSC	10.658	Down-regulation
Atypical_PIKK_ATR_ATR_ST	Q01094	E2F1	Q13535	ATR	S352	L351V	351	Missense	proximal	-1	no	10.785	10.570	EPSD	GDSC;CCLE	10.658	Loss
Atypical_PIKK_ATR_ATR_ST	Q01094	E2F1	Q13535	ATR	S352	S349Y	349	Missense	distal	-3	no	10.785	11.621	EPSD	GDSC;CCLE	10.658	Up-regulation
Atypical_PIKK_ATR_ATR_ST	Q01094	E2F1	Q13535	ATR	S364	P357Q	357	Missense	distal	-7	no	10.805	10.762	EPSD	GDSC	10.658	Down-regulation
Atypical_PIKK_ATR_ATR_ST	P04637	TP53	Q13535	ATR	S6	M1K	1	Missense	distal	-5	no	10.901	11.000	EPSD	GDSC	10.658	Up-regulation
Atypical_PIKK_ATR_ATR_ST	P04637	TP53	Q13535	ATR	S37	Q38*	38	Missense	proximal	1	no	17.659	14.347	PhosphoSitePlus;EPSD	GDSC	10.658	Down-regulation
Atypical_PIKK_ATR_ATR_ST	P04637	TP53	Q13535	ATR	T55	E56*	56	Missense	proximal	1	no	9.545	12.153	EPSD	GDSC	10.658	Gain
Atypical_PIKK_ATR_ATR_ST	P04637	TP53	Q13535	ATR	S99	K101*	101	Missense	proximal	2	no	13.266	10.965	EPSD	GDSC	10.658	Down-regulation
Atypical_PIKK_ATR_ATR_ST	P04637	TP53	Q13535	ATR	S99	Q100*	100	Missense	proximal	1	no	13.266	9.954	EPSD	GDSC	10.658	Loss
Atypical_PIKK_ATR_ATR_ST	P04637	TP53	Q13535	ATR	S99	S94*	94	Missense	distal	-5	no	13.266	13.714	EPSD	GDSC	10.658	Up-regulation
Atypical_PIKK_ATR_ATR_ST	P04637	TP53	Q13535	ATR	S106	K101*	101	Missense	distal	-5	no	11.409	11.861	EPSD	GDSC	10.658	Up-regulation
Atypical_PIKK_ATR_ATR_ST	P04637	TP53	Q13535	ATR	S106	Q100*	100	Missense	distal	-6	no	11.409	11.562	EPSD	GDSC	10.658	Up-regulation
Atypical_PIKK_ATR_ATR_ST	P04637	TP53	Q13535	ATR	S106	Y107*	107	Missense	proximal	1	no	11.409	14.410	EPSD	GDSC	10.658	Up-regulation
Atypical_PIKK_ATR_ATR_ST	P04637	TP53	Q13535	ATR	T211	R213*	213	Missense	proximal	2	no	10.866	8.958	EPSD	GDSC	10.658	Loss
Atypical_PIKK_ATR_ATR_ST	P04637	TP53	Q13535	ATR	T211	R209*	209	Missense	proximal	-2	no	10.866	11.729	EPSD	GDSC	10.658	Up-regulation
Atypical_PIKK_ATR_ATR_ST	P04637	TP53	Q13535	ATR	T211	E204*	204	Missense	distal	-7	no	10.866	10.545	EPSD	GDSC	10.658	Loss
Atypical_PIKK_ATR_ATR_ST	Q96SD1	DCLRE1C	Q13535	ATR	S548	Q546E	546	Missense	proximal	-2	no	14.606	14.571	EPSD	GDSC	10.658	Down-regulation
Atypical_PIKK_ATR_ATR_ST	Q96SD1	DCLRE1C	Q13535	ATR	S553	Q546E	546	Missense	distal	-7	no	14.312	14.357	EPSD	GDSC	10.658	Up-regulation
Atypical_PIKK_ATR_ATR_ST	Q8WVB6	CHTF18	Q13535	ATR	S405	R410S	410	Missense	distal	5	no	11.745	11.734	EPSD	GDSC;CCLE	10.658	Down-regulation
Atypical_PIKK_ATR_ATR_ST	Q8WVB6	CHTF18	Q13535	ATR	T778	L773F	773	Missense	distal	-5	no	11.475	11.519	EPSD	GDSC;CCLE	10.658	Up-regulation
Atypical_PIKK_ATR_ATR_ST	Q8WVB6	CHTF18	Q13535	ATR	T778	R784C	784	Missense	distal	6	no	11.475	11.688	EPSD	GDSC;CCLE	10.658	Up-regulation
Atypical_PIKK_ATR_ATR_ST	Q8WVB6	CHTF18	Q13535	ATR	T778	T783S	783	Missense	distal	5	no	11.475	11.467	EPSD	GDSC;CCLE	10.658	Down-regulation
Atypical_PIKK_ATR_ATR_ST	P23025	XPA	Q13535	ATR	S173	V166A	166	Missense	distal	-7	no	16.194	16.215	EPSD;PhosphoSitePlus	GDSC	10.658	Up-regulation
Atypical_PIKK_ATR_ATR_ST	P08047	SP1	Q13535	ATR	S73	A66G	66	Missense	distal	-7	no	12.796	12.783	EPSD	GDSC;CCLE	10.658	Down-regulation
Atypical_PIKK_ATR_ATR_ST	P08047	SP1	Q13535	ATR	S732	T737A	737	Missense	distal	5	no	11.680	11.683	EPSD	GDSC	10.658	Up-regulation
Atypical_PIKK_ATR_ATR_ST	P08047	SP1	Q13535	ATR	S732	G736V	736	Missense	distal	4	no	11.680	11.074	EPSD	GDSC;CCLE	10.658	Down-regulation
Atypical_PIKK_ATR_ATR_ST	P08047	SP1	Q13535	ATR	S732	A738T	738	Missense	distal	6	no	11.680	11.959	EPSD	GDSC;CCLE	10.658	Up-regulation
Atypical_PIKK_ATR_ATR_ST	P08047	SP1	Q13535	ATR	T739	T737A	737	Missense	proximal	-2	no	10.850	11.323	EPSD	GDSC	10.658	Up-regulation
Atypical_PIKK_ATR_ATR_ST	P08047	SP1	Q13535	ATR	T739	G736V	736	Missense	distal	-3	no	10.850	11.249	EPSD	GDSC;CCLE	10.658	Up-regulation
Atypical_PIKK_ATR_ATR_ST	P08047	SP1	Q13535	ATR	T739	A738T	738	Missense	proximal	-1	no	10.850	10.619	EPSD	GDSC;CCLE	10.658	Loss
Atypical_PIKK_ATR_ATR_ST	P38398	BRCA1	Q13535	ATR	S127	I124V	124	Missense	distal	-3	no	10.588	11.004	EPSD	GDSC;CCLE	10.658	Gain
Atypical_PIKK_ATR_ATR_ST	P38398	BRCA1	Q13535	ATR	S127	A134D	134	Missense	distal	7	no	10.588	10.675	EPSD	GDSC;CCLE	10.658	Gain
Atypical_PIKK_ATR_ATR_ST	P38398	BRCA1	Q13535	ATR	S956	L954I	954	Missense	proximal	-2	no	12.178	11.972	EPSD	GDSC;CCLE	10.658	Down-regulation
Atypical_PIKK_ATR_ATR_ST	P38398	BRCA1	Q13535	ATR	S956	G949C	949	Missense	distal	-7	no	12.178	12.000	EPSD	GDSC;CCLE	10.658	Down-regulation
Atypical_PIKK_ATR_ATR_ST	P38398	BRCA1	Q13535	ATR	S1239	K1233I	1233	Missense	distal	-6	no	14.724	14.799	EPSD	GDSC;CCLE	10.658	Up-regulation
Atypical_PIKK_ATR_ATR_ST	P38398	BRCA1	Q13535	ATR	S1239	N1236K	1236	Missense	distal	-3	no	14.724	13.564	EPSD	GDSC	10.658	Down-regulation
Atypical_PIKK_ATR_ATR_ST	P38398	BRCA1	Q13535	ATR	T1394	D1398N	1398	Missense	distal	4	no	13.794	14.483	EPSD	GDSC;CCLE	10.658	Up-regulation
Atypical_PIKK_ATR_ATR_ST	P38398	BRCA1	Q13535	ATR	S1457	A1453S	1453	Missense	distal	-4	no	19.606	19.085	EPSD;PhosphoSitePlus	GDSC	10.658	Down-regulation
Atypical_PIKK_ATR_ATR_ST	P38398	BRCA1	Q13535	ATR	S1524	Q1518H	1518	Missense	distal	-6	no	16.882	16.896	EPSD;PhosphoSitePlus	GDSC	10.658	Up-regulation
Atypical_PIKK_ATR_ATR_ST	P38398	BRCA1	Q13535	ATR	S1595	A1599V	1599	Missense	distal	4	no	12.461	12.321	EPSD	GDSC;CCLE	10.658	Down-regulation
Atypical_PIKK_ATR_ATR_ST	P38398	BRCA1	Q13535	ATR	S1595	S1596A	1596	Missense	proximal	1	no	12.461	7.710	EPSD	GDSC	10.658	Loss
Atypical_PIKK_ATR_ATR_ST	Q9Y248	GINS2	Q13535	ATR	T180	D184G	184	Missense	distal	4	no	10.030	10.851	EPSD	GDSC;CCLE	10.658	Gain
Atypical_PIKK_ATR_ATR_ST	Q9Y248	GINS2	Q13535	ATR	S182	D184G	184	Missense	proximal	2	no	11.861	13.407	PhosphoSitePlus	GDSC;CCLE	10.658	Up-regulation
Atypical_PIKK_ATR_ATR_ST	O43543	XRCC2	Q13535	ATR	S247	F241L	241	Missense	distal	-6	no	14.696	14.726	PhosphoSitePlus	GDSC;CCLE	10.658	Up-regulation
Atypical_PIKK_ATR_ATR_ST	Q9UBU7	DBF4	Q13535	ATR	T98	S103F	103	Missense	distal	5	no	12.350	12.362	EPSD	GDSC;CCLE	10.658	Up-regulation
Atypical_PIKK_ATR_ATR_ST	Q9UBU7	DBF4	Q13535	ATR	S413	L409P	409	Missense	distal	-4	no	9.611	10.811	EPSD	GDSC;CCLE	10.658	Gain
Atypical_PIKK_ATR_ATR_ST	Q9UBU7	DBF4	Q13535	ATR	T449	R445K	445	Missense	distal	-4	no	15.505	16.407	EPSD;PhosphoSitePlus	GDSC;CCLE	10.658	Up-regulation
Atypical_PIKK_ATR_ATR_ST	Q9UBU7	DBF4	Q13535	ATR	T449	I444V	444	Missense	distal	-5	no	15.505	15.400	EPSD;PhosphoSitePlus	GDSC;CCLE	10.658	Down-regulation
Atypical_PIKK_ATR_ATR_ST	Q9UBU7	DBF4	Q13535	ATR	S502	T497A	497	Missense	distal	-5	no	18.004	18.088	PhosphoSitePlus;EPSD	GDSC;CCLE	10.658	Up-regulation
Atypical_PIKK_ATR_ATR_ST	Q8IYD8	FANCM	Q13535	ATR	S1045	A1042T	1042	Missense	distal	-3	no	11.722	11.160	PhosphoSitePlus	GDSC;CCLE	10.658	Down-regulation
Atypical_PIKK_ATR_ATR_ST	Q8IYD8	FANCM	Q13535	ATR	S2004	M2010V	2010	Missense	distal	6	no	10.663	10.890	EPSD	GDSC;CCLE	10.658	Up-regulation
Atypical_PIKK_ATR_ATR_ST	P27707	DCK	Q13535	ATR	T64	N60D	60	Missense	distal	-4	no	13.776	14.385	EPSD	GDSC;CCLE	10.658	Up-regulation
Atypical_PIKK_ATR_ATR_ST	P27707	DCK	Q13535	ATR	S74	N80S	80	Missense	distal	6	no	15.619	15.505	PhosphoSitePlus	GDSC	10.658	Down-regulation
Atypical_PIKK_ATR_ATR_ST	Q9BXW9	FANCD2	Q13535	ATR	S15	S10P	10	Missense	distal	-5	no	13.481	13.510	EPSD	GDSC	10.658	Up-regulation
Atypical_PIKK_ATR_ATR_ST	Q9BXW9	FANCD2	Q13535	ATR	S319	S319F	319	Missense	central	0	yes	15.682	0.000	EPSD	GDSC	10.658	Loss
Atypical_PIKK_ATR_ATR_ST	Q9BXW9	FANCD2	Q13535	ATR	T596	P593S	593	Missense	distal	-3	no	14.160	13.883	EPSD;PhosphoSitePlus	GDSC	10.658	Down-regulation
Atypical_PIKK_ATR_ATR_ST	Q9BXW9	FANCD2	Q13535	ATR	T596	L602V	602	Missense	distal	6	no	14.160	14.271	EPSD;PhosphoSitePlus	GDSC;CCLE	10.658	Up-regulation
Atypical_PIKK_ATR_ATR_ST	Q9BXW9	FANCD2	Q13535	ATR	T608	L614*	614	Missense	distal	6	no	17.179	16.527	EPSD;PhosphoSitePlus	GDSC	10.658	Down-regulation
Atypical_PIKK_ATR_ATR_ST	Q9BXW9	FANCD2	Q13535	ATR	T608	S612P	612	Missense	distal	4	no	17.179	17.266	EPSD;PhosphoSitePlus	GDSC	10.658	Up-regulation
Atypical_PIKK_ATR_ATR_ST	Q9BXW9	FANCD2	Q13535	ATR	T608	L602V	602	Missense	distal	-6	no	17.179	17.147	EPSD;PhosphoSitePlus	GDSC;CCLE	10.658	Down-regulation
Atypical_PIKK_ATR_ATR_ST	Q9BXW9	FANCD2	Q13535	ATR	S1404	D1410Y	1410	Missense	distal	6	no	15.589	15.282	EPSD	GDSC;CCLE	10.658	Down-regulation
Atypical_PIKK_ATR_ATR_ST	Q9BXW9	FANCD2	Q13535	ATR	S1418	Q1419K	1419	Missense	proximal	1	no	14.007	3.041	EPSD	GDSC;CCLE	10.658	Loss
Atypical_PIKK_ATR_ATR_ST	P06748	NPM1	Q13535	ATR	S43	N38D	38	Missense	distal	-5	no	12.372	12.398	EPSD	GDSC;CCLE	10.658	Up-regulation
Atypical_PIKK_ATR_ATR_ST	P06748	NPM1	Q13535	ATR	T279	E282V	282	Missense	distal	3	no	10.330	10.744	EPSD	GDSC	10.658	Gain
Atypical_PIKK_ATR_ATR_ST	P15927	RPA2	Q13535	ATR	S72	E70K	70	Missense	proximal	-2	no	15.886	15.985	EPSD;PhosphoSitePlus	GDSC;CCLE	10.658	Up-regulation
Atypical_PIKK_ATR_ATR_ST	Q9NZC9	SMARCAL1	Q13535	ATR	S115	A118T	118	Missense	distal	3	no	11.322	11.634	EPSD	GDSC;CCLE	10.658	Up-regulation
Atypical_PIKK_ATR_ATR_ST	Q9NZC9	SMARCAL1	Q13535	ATR	S115	M117V	117	Missense	proximal	2	no	11.322	11.553	EPSD	GDSC;CCLE	10.658	Up-regulation
Atypical_PIKK_ATR_ATR_ST	Q9NZC9	SMARCAL1	Q13535	ATR	S129	A127P	127	Missense	proximal	-2	no	11.361	10.637	EPSD	GDSC	10.658	Loss
Atypical_PIKK_ATR_ATR_ST	Q9NZC9	SMARCAL1	Q13535	ATR	S919	M922T	922	Missense	distal	3	no	11.858	12.200	EPSD	GDSC	10.658	Up-regulation
Atypical_PIKK_ATR_ATR_ST	Q9NZC9	SMARCAL1	Q13535	ATR	S919	G923A	923	Missense	distal	4	no	11.858	11.391	EPSD	GDSC;CCLE	10.658	Down-regulation
Atypical_PIKK_ATR_ATR_ST	Q14683	SMC1A	Q13535	ATR	S703	G707E	707	Missense	distal	4	no	14.499	13.488	EPSD	GDSC;CCLE	10.658	Down-regulation
Atypical_PIKK_ATR_ATR_ST	Q14683	SMC1A	Q13535	ATR	S715	K713T	713	Missense	proximal	-2	no	12.596	12.503	EPSD	GDSC;CCLE	10.658	Down-regulation
Atypical_PIKK_ATR_ATR_ST	P54132	BLM	Q13535	ATR	T20	R15H	15	Missense	distal	-5	no	10.871	10.809	EPSD	GDSC;CCLE	10.658	Down-regulation
Atypical_PIKK_ATR_ATR_ST	P54132	BLM	Q13535	ATR	S314	E307G	307	Missense	distal	-7	no	11.794	11.717	EPSD	GDSC;CCLE	10.658	Down-regulation
Atypical_PIKK_ATR_ATR_ST	P54132	BLM	Q13535	ATR	T337	S338*	338	Missense	proximal	1	no	8.215	10.880	EPSD	GDSC	10.658	Gain
Atypical_PIKK_ATR_ATR_ST	P54132	BLM	Q13535	ATR	S460	H457R	457	Missense	distal	-3	no	10.853	11.221	EPSD	GDSC;CCLE	10.658	Up-regulation
Atypical_PIKK_ATR_ATR_ST	P54132	BLM	Q13535	ATR	S502	S499F	499	Missense	distal	-3	no	10.599	11.458	EPSD	GDSC;CCLE	10.658	Gain
Atypical_PIKK_ATR_ATR_ST	P54132	BLM	Q13535	ATR	T907	D906N	906	Missense	proximal	-1	no	12.034	12.325	EPSD	GDSC;CCLE	10.658	Up-regulation
Atypical_PIKK_ATR_ATR_ST	Q8IX01	SUGP2	Q13535	ATR	S153	G149D	149	Missense	distal	-4	no	14.834	16.184	EPSD	GDSC;CCLE	10.658	Up-regulation
Atypical_PIKK_ATR_ATR_ST	Q8IX01	SUGP2	Q13535	ATR	S251	L244F	244	Missense	distal	-7	no	10.692	10.749	EPSD	GDSC;CCLE	10.658	Up-regulation
Atypical_PIKK_ATR_ATR_ST	Q8IX01	SUGP2	Q13535	ATR	T265	R260L	260	Missense	distal	-5	no	11.723	11.724	EPSD	GDSC;CCLE	10.658	Up-regulation
Atypical_PIKK_ATR_ATR_ST	Q8IX01	SUGP2	Q13535	ATR	S537	L531M	531	Missense	distal	-6	no	12.052	12.007	EPSD	GDSC;CCLE	10.658	Down-regulation
Atypical_PIKK_ATR_ATR_ST	Q8IX01	SUGP2	Q13535	ATR	S940	G945V	945	Missense	distal	5	no	14.359	14.355	EPSD	GDSC	10.658	Down-regulation
Atypical_PIKK_ATR_ATR_ST	Q13315	ATM	Q13535	ATR	S1878	H1876Q	1876	Missense	proximal	-2	no	13.195	13.562	EPSD	GDSC;CCLE	10.658	Up-regulation
Atypical_PIKK_ATR_ATR_ST	Q13315	ATM	Q13535	ATR	S2162	Y2167*	2167	Missense	distal	5	no	12.542	12.557	EPSD	GDSC	10.658	Up-regulation
Atypical_PIKK_ATR_ATR_ST	Q13315	ATM	Q13535	ATR	S2242	R2244T	2244	Missense	proximal	2	no	14.196	14.079	EPSD	GDSC;CCLE	10.658	Down-regulation
Atypical_PIKK_ATR_ATR_ST	Q13315	ATM	Q13535	ATR	S2592	V2587M	2587	Missense	distal	-5	no	13.565	13.364	EPSD	GDSC;CCLE	10.658	Down-regulation
Atypical_PIKK_ATR_ATR_ST	P16220	CREB1	Q13535	ATR	S111	S111L	111	Missense	central	0	yes	13.253	0.000	EPSD	GDSC;CCLE	10.658	Loss
Atypical_PIKK_ATR_ATR_ST	O96017	CHEK2	Q13535	ATR	T68	S73F	73	Missense	distal	5	no	14.803	14.815	PhosphoSitePlus	GDSC;CCLE	10.658	Up-regulation
Atypical_PIKK_ATR_ATR_ST	Q13535	ATR	Q13535	ATR	S61	T64A	64	Missense	distal	3	no	13.209	12.897	EPSD	GDSC	10.658	Down-regulation
Atypical_PIKK_ATR_ATR_ST	Q13535	ATR	Q13535	ATR	S428	R432H	432	Missense	distal	4	no	12.064	11.610	EPSD	GDSC;CCLE	10.658	Down-regulation
Atypical_PIKK_ATR_ATR_ST	Q13535	ATR	Q13535	ATR	S1140	Q1137*	1137	Missense	distal	-3	no	9.968	10.965	EPSD	GDSC	10.658	Gain
Atypical_PIKK_ATR_ATR_ST	Q13535	ATR	Q13535	ATR	T1589	D1586Y	1586	Missense	distal	-3	no	14.249	14.293	EPSD	GDSC;CCLE	10.658	Up-regulation
Atypical_PIKK_ATR_ATR_ST	Q13535	ATR	Q13535	ATR	S1876	L1881I	1881	Missense	distal	5	no	11.526	11.532	EPSD	GDSC;CCLE	10.658	Up-regulation
Atypical_PIKK_ATR_ATR_ST	Q13535	ATR	Q13535	ATR	S1876	G1873C	1873	Missense	distal	-3	no	11.526	11.897	EPSD	GDSC;CCLE	10.658	Up-regulation
Atypical_PIKK_ATR_ATR_ST	Q13535	ATR	Q13535	ATR	T1890	A1896V	1896	Missense	distal	6	no	13.617	13.830	EPSD	GDSC;CCLE	10.658	Up-regulation
Atypical_PIKK_ATR_ATR_ST	P35568	IRS1	Q13535	ATR	S24	H26R	26	Missense	proximal	2	no	11.040	11.272	EPSD	GDSC;CCLE	10.658	Up-regulation
Atypical_PIKK_ATR_ATR_ST	P35568	IRS1	Q13535	ATR	S270	R267C	267	Missense	distal	-3	no	14.440	14.314	PhosphoSitePlus	GDSC;CCLE	10.658	Down-regulation
Atypical_PIKK_ATR_ATR_ST	P35568	IRS1	Q13535	ATR	S547	A546V	546	Missense	proximal	-1	no	11.112	10.856	EPSD	GDSC;CCLE	10.658	Down-regulation
Atypical_PIKK_ATR_ATR_ST	P35568	IRS1	Q13535	ATR	S694	V689I	689	Missense	distal	-5	no	10.973	11.078	EPSD	GDSC	10.658	Up-regulation
Atypical_PIKK_ATR_ATR_ST	P35568	IRS1	Q13535	ATR	S741	P737S	737	Missense	distal	-4	no	10.880	10.555	EPSD	GDSC	10.658	Loss
Atypical_PIKK_ATR_ATR_ST	P35568	IRS1	Q13535	ATR	T1196	P1192L	1192	Missense	distal	-4	no	12.834	11.634	EPSD	GDSC;CCLE	10.658	Down-regulation
Atypical_PIKK_ATR_ATR_ST	P35568	IRS1	Q13535	ATR	T1196	P1202S	1202	Missense	distal	6	no	12.834	13.132	EPSD	GDSC	10.658	Up-regulation
Atypical_PIKK_ATR_ATR_ST	Q14191	WRN	Q13535	ATR	S462	D468V	468	Missense	distal	6	no	10.649	10.725	EPSD	GDSC	10.658	Gain
Atypical_PIKK_ATR_ATR_ST	Q14191	WRN	Q13535	ATR	T777	T781I	781	Missense	distal	4	no	11.892	12.524	EPSD	GDSC	10.658	Up-regulation
Atypical_PIKK_ATR_ATR_ST	Q14191	WRN	Q13535	ATR	T777	T781A	781	Missense	distal	4	no	11.892	12.143	EPSD	GDSC;CCLE	10.658	Up-regulation
Atypical_PIKK_ATR_ATR_ST	Q14191	WRN	Q13535	ATR	S1141	S1141L	1141	Missense	central	0	yes	16.282	0.000	PhosphoSitePlus	GDSC	10.658	Loss
Atypical_PIKK_ATR_ATR_ST	Q14191	WRN	Q13535	ATR	S1292	G1298V	1298	Missense	distal	6	no	14.128	14.257	EPSD	GDSC	10.658	Up-regulation
Atypical_PIKK_ATR_ATR_ST	P49736	MCM2	Q13535	ATR	T39	S40F	40	Missense	proximal	1	no	11.507	10.800	EPSD	GDSC;CCLE	10.658	Down-regulation
Atypical_PIKK_ATR_ATR_ST	P49736	MCM2	Q13535	ATR	T39	R44G	44	Missense	distal	5	no	11.507	11.501	EPSD	GDSC;CCLE	10.658	Down-regulation
Atypical_PIKK_ATR_ATR_ST	P49736	MCM2	Q13535	ATR	T39	P42L	42	Missense	distal	3	no	11.507	10.904	EPSD	GDSC;CCLE	10.658	Down-regulation
Atypical_PIKK_ATR_ATR_ST	P49736	MCM2	Q13535	ATR	S40	R44G	44	Missense	distal	4	no	10.040	10.756	EPSD	GDSC;CCLE	10.658	Gain
Atypical_PIKK_ATR_ATR_ST	P49736	MCM2	Q13535	ATR	S41	S40F	40	Missense	proximal	-1	no	13.128	13.129	EPSD	GDSC;CCLE	10.658	Up-regulation
Atypical_PIKK_ATR_ATR_ST	P49736	MCM2	Q13535	ATR	S41	R44G	44	Missense	distal	3	no	13.128	13.070	EPSD	GDSC;CCLE	10.658	Down-regulation
Atypical_PIKK_ATR_ATR_ST	P49736	MCM2	Q13535	ATR	S41	P42L	42	Missense	proximal	1	no	13.128	12.562	EPSD	GDSC;CCLE	10.658	Down-regulation
Atypical_PIKK_ATR_ATR_ST	P49736	MCM2	Q13535	ATR	S108	R115L	115	Missense	distal	7	no	15.987	15.925	PhosphoSitePlus	GDSC;CCLE	10.658	Down-regulation
Atypical_PIKK_ATR_ATR_ST	P49736	MCM2	Q13535	ATR	S769	V764A	764	Missense	distal	-5	no	10.684	10.681	EPSD	GDSC;CCLE	10.658	Down-regulation
Atypical_PIKK_ATR_ATR_ST	P49736	MCM2	Q13535	ATR	T805	K807R	807	Missense	proximal	2	no	13.074	12.680	EPSD	GDSC	10.658	Down-regulation
Atypical_PIKK_ATR_ATR_ST	O15360	FANCA	Q13535	ATR	T381	Q382E	382	Missense	proximal	1	no	13.731	7.811	EPSD	GDSC;CCLE	10.658	Loss
Atypical_PIKK_ATR_ATR_ST	O15360	FANCA	Q13535	ATR	S1449	A1442G	1442	Missense	distal	-7	no	16.222	16.209	PhosphoSitePlus	GDSC;CCLE	10.658	Down-regulation
Atypical_PIKK_ATR_ATR_ST	O15360	FANCA	Q13535	ATR	S1449	E1451Q	1451	Missense	proximal	2	no	16.222	14.969	PhosphoSitePlus	GDSC;CCLE	10.658	Down-regulation
Atypical_PIKK_ATR_ATR_ST	O15360	FANCA	Q13535	ATR	S1449	E1451K	1451	Missense	proximal	2	no	16.222	15.273	PhosphoSitePlus	GDSC;CCLE	10.658	Down-regulation
Atypical_PIKK_ATR_ATR_ST	Q9UER7	DAXX	Q13535	ATR	S33	A32T	32	Missense	proximal	-1	no	11.686	11.456	EPSD	GDSC;CCLE	10.658	Down-regulation
Atypical_PIKK_ATR_ATR_ST	Q9UER7	DAXX	Q13535	ATR	S176	S176A	176	Missense	central	0	yes	13.958	0.000	EPSD	GDSC;CCLE	10.658	Loss
Atypical_PIKK_ATR_ATR_ST	Q9UER7	DAXX	Q13535	ATR	S176	R182H	182	Missense	distal	6	no	13.958	14.033	EPSD	GDSC;CCLE	10.658	Up-regulation
Atypical_PIKK_ATR_ATR_ST	Q9UER7	DAXX	Q13535	ATR	S424	C427Y	427	Missense	distal	3	no	17.001	16.386	PhosphoSitePlus	GDSC;CCLE	10.658	Down-regulation
Atypical_PIKK_ATR_ATR_ST	Q9UER7	DAXX	Q13535	ATR	S688	D687V	687	Missense	proximal	-1	no	11.222	11.055	EPSD	GDSC	10.658	Down-regulation
Atypical_PIKK_ATR_ATR_ST	Q9UER7	DAXX	Q13535	ATR	S723	V724M	724	Missense	proximal	1	no	-4.001	11.608	EPSD	GDSC	10.658	Gain
Atypical_PIKK_ATR_ATR_ST	Q9UER7	DAXX	Q13535	ATR	T726	V724M	724	Missense	proximal	-2	no	12.988	13.101	EPSD	GDSC	10.658	Up-regulation
Atypical_PIKK_ATR_ATR_ST	Q03164	KMT2A	Q13535	ATR	S153	E146K	146	Missense	distal	-7	no	10.699	10.682	EPSD	GDSC;CCLE	10.658	Down-regulation
Atypical_PIKK_ATR_ATR_ST	Q03164	KMT2A	Q13535	ATR	S470	M472I	472	Missense	proximal	2	no	14.231	13.151	EPSD	GDSC;CCLE	10.658	Down-regulation
Atypical_PIKK_ATR_ATR_ST	Q03164	KMT2A	Q13535	ATR	T506	E502K	502	Missense	distal	-4	no	11.364	10.954	EPSD	GDSC	10.658	Down-regulation
Atypical_PIKK_ATR_ATR_ST	Q03164	KMT2A	Q13535	ATR	T1382	L1380F	1380	Missense	proximal	-2	no	11.561	11.457	EPSD	GDSC;CCLE	10.658	Down-regulation
Atypical_PIKK_ATR_ATR_ST	Q03164	KMT2A	Q13535	ATR	S2110	S2105R	2105	Missense	distal	-5	no	14.849	15.031	EPSD	GDSC	10.658	Up-regulation
Atypical_PIKK_ATR_ATR_ST	Q03164	KMT2A	Q13535	ATR	T2791	K2790E	2790	Missense	proximal	-1	no	14.316	14.565	EPSD	GDSC;CCLE	10.658	Up-regulation
Atypical_PIKK_ATR_ATR_ST	Q03164	KMT2A	Q13535	ATR	S3053	P3056T	3056	Missense	distal	3	no	11.166	10.880	EPSD	GDSC;CCLE	10.658	Down-regulation
Atypical_PIKK_ATR_ATR_ST	Q03164	KMT2A	Q13535	ATR	S3057	P3056T	3056	Missense	proximal	-1	no	14.538	14.369	EPSD	GDSC;CCLE	10.658	Down-regulation
Atypical_PIKK_ATR_ATR_ST	Q03164	KMT2A	Q13535	ATR	S3508	S3502F	3502	Missense	distal	-6	no	12.226	12.305	EPSD	GDSC;CCLE	10.658	Up-regulation
Atypical_PIKK_ATR_ATR_ST	Q02952	AKAP12	Q13535	ATR	T548	Q549R	549	Missense	proximal	1	no	12.896	5.900	EPSD	GDSC;CCLE	10.658	Loss
Atypical_PIKK_ATR_ATR_ST	Q02952	AKAP12	Q13535	ATR	S554	Q549R	549	Missense	distal	-5	no	12.675	12.768	EPSD	GDSC;CCLE	10.658	Up-regulation
Atypical_PIKK_ATR_ATR_ST	Q02952	AKAP12	Q13535	ATR	S887	H890Y	890	Missense	distal	3	no	14.016	13.126	EPSD	GDSC;CCLE	10.658	Down-regulation
Atypical_PIKK_ATR_ATR_ST	Q02952	AKAP12	Q13535	ATR	T1039	Q1040L	1040	Missense	proximal	1	no	14.575	9.141	EPSD	GDSC	10.658	Loss
Atypical_PIKK_ATR_ATR_ST	Q02952	AKAP12	Q13535	ATR	S1149	V1147I	1147	Missense	proximal	-2	no	14.427	14.668	EPSD	GDSC;CCLE	10.658	Up-regulation
Atypical_PIKK_ATR_ATR_ST	Q7Z6Z7	HUWE1	Q13535	ATR	S525	F524L	524	Missense	proximal	-1	no	11.995	12.229	EPSD	GDSC;CCLE	10.658	Up-regulation
Atypical_PIKK_ATR_ATR_ST	Q7Z6Z7	HUWE1	Q13535	ATR	S1030	E1023K	1023	Missense	distal	-7	no	11.312	11.295	EPSD	GDSC;CCLE	10.658	Down-regulation
Atypical_PIKK_ATR_ATR_ST	Q7Z6Z7	HUWE1	Q13535	ATR	S1218	P1212S	1212	Missense	distal	-6	no	11.806	11.761	EPSD	GDSC;CCLE	10.658	Down-regulation
Atypical_PIKK_ATR_ATR_ST	Q7Z6Z7	HUWE1	Q13535	ATR	S2391	S2391G	2391	Missense	central	0	yes	16.807	0.000	PhosphoSitePlus	GDSC	10.658	Loss
Atypical_PIKK_ATR_ATR_ST	Q7Z6Z7	HUWE1	Q13535	ATR	S2636	T2633I	2633	Missense	distal	-3	no	11.823	11.569	EPSD	GDSC;CCLE	10.658	Down-regulation
Atypical_PIKK_ATR_ATR_ST	Q7Z6Z7	HUWE1	Q13535	ATR	T2640	T2633I	2633	Missense	distal	-7	no	14.433	14.374	EPSD	GDSC;CCLE	10.658	Down-regulation
Atypical_PIKK_ATR_ATR_ST	Q7Z6Z7	HUWE1	Q13535	ATR	S2850	S2850C	2850	Missense	central	0	yes	13.939	0.000	EPSD	GDSC	10.658	Loss
Atypical_PIKK_ATR_ATR_ST	Q7Z6Z7	HUWE1	Q13535	ATR	S2904	R2903S	2903	Missense	proximal	-1	no	10.709	10.581	EPSD	GDSC;CCLE	10.658	Loss
Atypical_PIKK_ATR_ATR_ST	Q7Z6Z7	HUWE1	Q13535	ATR	S3279	L3283F	3283	Missense	distal	4	no	10.988	10.770	EPSD	GDSC;CCLE	10.658	Down-regulation
Atypical_PIKK_ATR_ATR_ST	Q7Z6Z7	HUWE1	Q13535	ATR	S3797	A3792S	3792	Missense	distal	-5	no	13.897	13.801	EPSD	GDSC	10.658	Down-regulation
Atypical_PIKK_ATR_ATR_ST	Q9NZN8	CNOT2	Q13535	ATR	S190	G193R	193	Missense	distal	3	no	12.653	12.711	EPSD	GDSC	10.658	Up-regulation
Atypical_PIKK_ATR_ATR_ST	Q9NZN8	CNOT2	Q13535	ATR	S391	P392L	392	Missense	proximal	1	no	12.436	11.870	EPSD	GDSC;CCLE	10.658	Down-regulation
Atypical_PIKK_ATR_ATR_ST	Q9UH99	SUN2	Q13535	ATR	S160	R156Q	156	Missense	distal	-4	no	11.790	11.972	EPSD	GDSC	10.658	Up-regulation
Atypical_PIKK_ATR_ATR_ST	Q9UH99	SUN2	Q13535	ATR	S160	A158T	158	Missense	proximal	-2	no	11.790	11.317	EPSD	GDSC;CCLE	10.658	Down-regulation
Atypical_PIKK_ATR_ATR_ST	Q9UH99	SUN2	Q13535	ATR	S160	S153L	153	Missense	distal	-7	no	11.790	11.625	EPSD	GDSC;CCLE	10.658	Down-regulation
Atypical_PIKK_ATR_ATR_ST	Q9UH99	SUN2	Q13535	ATR	S381	R379W	379	Missense	proximal	-2	no	13.945	14.051	EPSD	GDSC;CCLE	10.658	Up-regulation
Atypical_PIKK_ATR_ATR_ST	Q9BUG6	ZSCAN5A	Q13535	ATR	T236	E231D	231	Missense	distal	-5	no	12.241	12.493	EPSD	GDSC;CCLE	10.658	Up-regulation
Atypical_PIKK_ATR_ATR_ST	Q9BUG6	ZSCAN5A	Q13535	ATR	T236	P233L	233	Missense	distal	-3	no	12.241	12.535	EPSD	GDSC;CCLE	10.658	Up-regulation
Atypical_PIKK_ATR_ATR_ST	O94880	PHF14	Q13535	ATR	T162	V166L	166	Missense	distal	4	no	11.150	11.224	EPSD	GDSC;CCLE	10.658	Up-regulation
Atypical_PIKK_ATR_ATR_ST	O94880	PHF14	Q13535	ATR	T162	A159V	159	Missense	distal	-3	no	11.150	10.751	EPSD	GDSC;CCLE	10.658	Down-regulation
Atypical_PIKK_ATR_ATR_ST	O94880	PHF14	Q13535	ATR	T162	S163F	163	Missense	proximal	1	no	11.150	10.443	EPSD	GDSC	10.658	Loss
Atypical_PIKK_ATR_ATR_ST	O94880	PHF14	Q13535	ATR	S163	V166L	166	Missense	distal	3	no	11.998	11.231	EPSD	GDSC;CCLE	10.658	Down-regulation
Atypical_PIKK_ATR_ATR_ST	O94880	PHF14	Q13535	ATR	S163	A159V	159	Missense	distal	-4	no	11.998	11.009	EPSD	GDSC;CCLE	10.658	Down-regulation
Atypical_PIKK_ATR_ATR_ST	O94880	PHF14	Q13535	ATR	S163	S163F	163	Missense	central	0	yes	11.998	0.000	EPSD	GDSC	10.658	Loss
Atypical_PIKK_ATR_ATR_ST	O94880	PHF14	Q13535	ATR	T292	S296I	296	Missense	distal	4	no	10.322	11.005	EPSD	GDSC;CCLE	10.658	Gain
Atypical_PIKK_ATR_ATR_ST	O94880	PHF14	Q13535	ATR	S294	S296I	296	Missense	proximal	2	no	17.072	16.399	PhosphoSitePlus	GDSC;CCLE	10.658	Down-regulation
Atypical_PIKK_ATR_ATR_ST	O94880	PHF14	Q13535	ATR	S302	S296I	296	Missense	distal	-6	no	11.437	11.521	EPSD	GDSC;CCLE	10.658	Up-regulation
Atypical_PIKK_ATR_ATR_ST	O94880	PHF14	Q13535	ATR	S601	N597I	597	Missense	distal	-4	no	12.380	10.816	EPSD	GDSC;CCLE	10.658	Down-regulation
Atypical_PIKK_ATR_ATR_ST	Q8N4S0	CCDC82	Q13535	ATR	S131	H129R	129	Missense	proximal	-2	no	13.651	14.096	EPSD	GDSC;CCLE	10.658	Up-regulation
Atypical_PIKK_ATR_ATR_ST	Q8N4S0	CCDC82	Q13535	ATR	S154	E156Q	156	Missense	proximal	2	no	16.298	15.045	PhosphoSitePlus	GDSC;CCLE	10.658	Down-regulation
Atypical_PIKK_ATR_ATR_ST	Q8N4S0	CCDC82	Q13535	ATR	S154	S154N	154	Missense	central	0	yes	16.298	0.000	PhosphoSitePlus	GDSC	10.658	Loss
Atypical_PIKK_ATR_ATR_ST	Q8N4S0	CCDC82	Q13535	ATR	S320	L322V	322	Missense	proximal	2	no	13.838	15.441	EPSD	GDSC;CCLE	10.658	Up-regulation
Atypical_PIKK_ATR_ATR_ST	Q01844	EWSR1	Q13535	ATR	S274	S274R	274	Missense	central	0	yes	13.008	0.000	EPSD	GDSC;CCLE	10.658	Loss
Atypical_PIKK_ATR_ATR_ST	Q01844	EWSR1	Q13535	ATR	S358	D355E	355	Missense	distal	-3	no	11.651	11.058	EPSD	GDSC	10.658	Down-regulation
Atypical_PIKK_ATR_ATR_ST	Q14676	MDC1	Q13535	ATR	T4	E2D	2	Missense	proximal	-2	no	13.599	13.695	EPSD	GDSC;CCLE	10.658	Up-regulation
Atypical_PIKK_ATR_ATR_ST	Q14676	MDC1	Q13535	ATR	S20	S23F	23	Missense	distal	3	no	10.976	9.945	EPSD	GDSC;CCLE	10.658	Loss
Atypical_PIKK_ATR_ATR_ST	Q14676	MDC1	Q13535	ATR	S20	E14*	14	Missense	distal	-6	no	10.976	11.148	EPSD	GDSC	10.658	Up-regulation
Atypical_PIKK_ATR_ATR_ST	Q14676	MDC1	Q13535	ATR	S23	S23F	23	Missense	central	0	yes	11.770	0.000	EPSD	GDSC;CCLE	10.658	Loss
Atypical_PIKK_ATR_ATR_ST	Q14676	MDC1	Q13535	ATR	S141	R142Q	142	Missense	proximal	1	no	8.142	15.137	EPSD	GDSC;CCLE	10.658	Gain
Atypical_PIKK_ATR_ATR_ST	Q14676	MDC1	Q13535	ATR	T157	R161G	161	Missense	distal	4	no	14.762	15.478	EPSD	GDSC;CCLE	10.658	Up-regulation
Atypical_PIKK_ATR_ATR_ST	Q14676	MDC1	Q13535	ATR	S218	A213P	213	Missense	distal	-5	no	13.752	13.685	EPSD	GDSC;CCLE	10.658	Down-regulation
Atypical_PIKK_ATR_ATR_ST	Q14676	MDC1	Q13535	ATR	S218	F214L	214	Missense	distal	-4	no	13.752	13.160	EPSD	GDSC	10.658	Down-regulation
Atypical_PIKK_ATR_ATR_ST	Q14676	MDC1	Q13535	ATR	S329	T331I	331	Missense	proximal	2	no	11.485	11.203	EPSD	GDSC;CCLE	10.658	Down-regulation
Atypical_PIKK_ATR_ATR_ST	Q14676	MDC1	Q13535	ATR	S372	L369M	369	Missense	distal	-3	no	13.331	12.775	EPSD	GDSC;CCLE	10.658	Down-regulation
Atypical_PIKK_ATR_ATR_ST	Q14676	MDC1	Q13535	ATR	T378	E382*	382	Missense	distal	4	no	10.493	12.382	EPSD	GDSC	10.658	Gain
Atypical_PIKK_ATR_ATR_ST	Q14676	MDC1	Q13535	ATR	S505	D502N	502	Missense	distal	-3	no	13.182	13.474	EPSD	GDSC;CCLE	10.658	Up-regulation
Atypical_PIKK_ATR_ATR_ST	Q14676	MDC1	Q13535	ATR	S505	P506H	506	Missense	proximal	1	no	13.182	0.532	EPSD	GDSC;CCLE	10.658	Loss
Atypical_PIKK_ATR_ATR_ST	Q14676	MDC1	Q13535	ATR	S505	R512K	512	Missense	distal	7	no	13.182	13.069	EPSD	GDSC;CCLE	10.658	Down-regulation
Atypical_PIKK_ATR_ATR_ST	Q14676	MDC1	Q13535	ATR	S513	P506H	506	Missense	distal	-7	no	15.062	15.039	PhosphoSitePlus	GDSC;CCLE	10.658	Down-regulation
Atypical_PIKK_ATR_ATR_ST	Q14676	MDC1	Q13535	ATR	S513	R512K	512	Missense	proximal	-1	no	15.062	14.828	PhosphoSitePlus	GDSC;CCLE	10.658	Down-regulation
Atypical_PIKK_ATR_ATR_ST	Q14676	MDC1	Q13535	ATR	T725	L730I	730	Missense	distal	5	no	10.959	10.965	EPSD	GDSC	10.658	Up-regulation
Atypical_PIKK_ATR_ATR_ST	Q14676	MDC1	Q13535	ATR	T725	G731D	731	Missense	distal	6	no	10.959	11.012	EPSD	GDSC;CCLE	10.658	Up-regulation
Atypical_PIKK_ATR_ATR_ST	Q14676	MDC1	Q13535	ATR	S1055	P1052S	1052	Missense	distal	-3	no	13.939	13.662	EPSD	GDSC;CCLE	10.658	Down-regulation
Atypical_PIKK_ATR_ATR_ST	Q14676	MDC1	Q13535	ATR	S1057	P1052S	1052	Missense	distal	-5	no	12.221	12.192	EPSD	GDSC;CCLE	10.658	Down-regulation
Atypical_PIKK_ATR_ATR_ST	Q14676	MDC1	Q13535	ATR	S1086	R1082M	1082	Missense	distal	-4	no	15.640	15.719	EPSD	GDSC;CCLE	10.658	Up-regulation
Atypical_PIKK_ATR_ATR_ST	Q14676	MDC1	Q13535	ATR	S1086	Q1083H	1083	Missense	distal	-3	no	15.640	15.456	EPSD	GDSC;CCLE	10.658	Down-regulation
Atypical_PIKK_ATR_ATR_ST	Q14676	MDC1	Q13535	ATR	S1130	T1131P	1131	Missense	proximal	1	no	6.177	10.828	EPSD	GDSC	10.658	Gain
Atypical_PIKK_ATR_ATR_ST	Q14676	MDC1	Q13535	ATR	S1184	T1183I	1183	Missense	proximal	-1	no	13.414	13.639	EPSD	GDSC;CCLE	10.658	Up-regulation
Atypical_PIKK_ATR_ATR_ST	Q14676	MDC1	Q13535	ATR	S1225	A1227V	1227	Missense	proximal	2	no	13.057	13.546	EPSD	GDSC	10.658	Up-regulation
Atypical_PIKK_ATR_ATR_ST	Q14676	MDC1	Q13535	ATR	S1276	V1278G	1278	Missense	proximal	2	no	11.168	11.470	EPSD	GDSC	10.658	Up-regulation
Atypical_PIKK_ATR_ATR_ST	Q14676	MDC1	Q13535	ATR	S1523	V1524L	1524	Missense	proximal	1	no	-2.581	11.680	EPSD	GDSC	10.658	Gain
Atypical_PIKK_ATR_ATR_ST	Q14676	MDC1	Q13535	ATR	S1563	G1558D	1558	Missense	distal	-5	no	10.615	10.768	EPSD	GDSC	10.658	Gain
Atypical_PIKK_ATR_ATR_ST	Q14676	MDC1	Q13535	ATR	T1622	T1623P	1623	Missense	proximal	1	no	6.452	11.103	EPSD	GDSC	10.658	Gain
Atypical_PIKK_ATR_ATR_ST	Q14676	MDC1	Q13535	ATR	S1702	E1699K	1699	Missense	distal	-3	no	12.752	12.477	EPSD	GDSC;CCLE	10.658	Down-regulation
Atypical_PIKK_ATR_ATR_ST	Q6PGQ7	BORA	Q13535	ATR	S27	S27G	27	Missense	central	0	yes	11.707	0.000	EPSD	GDSC;CCLE	10.658	Loss
Atypical_PIKK_ATR_ATR_ST	Q6PGQ7	BORA	Q13535	ATR	S41	T38I	38	Missense	distal	-3	no	11.228	10.973	EPSD	GDSC;CCLE	10.658	Down-regulation
Atypical_PIKK_ATR_ATR_ST	Q6PGQ7	BORA	Q13535	ATR	S41	A40T	40	Missense	proximal	-1	no	11.228	10.998	EPSD	GDSC;CCLE	10.658	Down-regulation
Atypical_PIKK_ATR_ATR_ST	Q6PGQ7	BORA	Q13535	ATR	S41	F45V	45	Missense	distal	4	no	11.228	11.372	EPSD	GDSC;CCLE	10.658	Up-regulation
Atypical_PIKK_ATR_ATR_ST	Q6PGQ7	BORA	Q13535	ATR	S262	A258V	258	Missense	distal	-4	no	11.833	10.845	EPSD	GDSC;CCLE	10.658	Down-regulation
Atypical_PIKK_ATR_ATR_ST	Q6PGQ7	BORA	Q13535	ATR	S262	G264*	264	Missense	proximal	2	no	11.833	8.713	EPSD	GDSC	10.658	Loss
Atypical_PIKK_ATR_ATR_ST	O00213	APBB1	Q13535	ATR	S287	S287C	287	Missense	central	0	yes	11.262	0.000	EPSD	GDSC;CCLE	10.658	Loss
Atypical_PIKK_ATR_ATR_ST	O00213	APBB1	Q13535	ATR	S287	S292I	292	Missense	distal	5	no	11.262	11.274	EPSD	GDSC;CCLE	10.658	Up-regulation
Atypical_PIKK_ATR_ATR_ST	O00213	APBB1	Q13535	ATR	S289	S287C	287	Missense	proximal	-2	no	16.933	17.573	EPSD	GDSC;CCLE	10.658	Up-regulation
Atypical_PIKK_ATR_ATR_ST	O00213	APBB1	Q13535	ATR	S289	S292I	292	Missense	distal	3	no	16.933	16.942	EPSD	GDSC;CCLE	10.658	Up-regulation
Atypical_PIKK_ATR_ATR_ST	O00213	APBB1	Q13535	ATR	S322	L329P	329	Missense	distal	7	no	13.484	13.486	EPSD	GDSC;CCLE	10.658	Up-regulation
Atypical_PIKK_ATR_ATR_ST	O00213	APBB1	Q13535	ATR	S347	E354*	354	Missense	distal	7	no	12.192	12.631	EPSD	GDSC	10.658	Up-regulation
Atypical_PIKK_ATR_ATR_ST	Q8TAQ2	SMARCC2	Q13535	ATR	S69	K75*	75	Missense	distal	6	no	11.623	10.861	EPSD	GDSC	10.658	Down-regulation
Atypical_PIKK_ATR_ATR_ST	Q8TAQ2	SMARCC2	Q13535	ATR	S387	S387G	387	Missense	central	0	yes	12.345	0.000	EPSD	GDSC;CCLE	10.658	Loss
Atypical_PIKK_ATR_ATR_ST	Q8TAQ2	SMARCC2	Q13535	ATR	S810	E811*	811	Missense	proximal	1	no	9.667	12.275	EPSD	GDSC	10.658	Gain
Atypical_PIKK_ATR_ATR_ST	Q8N163	CCAR2	Q13535	ATR	S43	L49I	49	Missense	distal	6	no	12.854	12.806	EPSD	GDSC	10.658	Down-regulation
Atypical_PIKK_ATR_ATR_ST	Q8N163	CCAR2	Q13535	ATR	S302	D301Y	301	Missense	proximal	-1	no	10.933	11.077	EPSD	GDSC;CCLE	10.658	Up-regulation
Atypical_PIKK_ATR_ATR_ST	Q8N163	CCAR2	Q13535	ATR	T454	G459R	459	Missense	distal	5	no	16.955	16.961	PhosphoSitePlus	GDSC;CCLE	10.658	Up-regulation
Atypical_PIKK_ATR_ATR_ST	O75717	WDHD1	Q13535	ATR	S853	S846N	846	Missense	distal	-7	no	10.850	10.716	EPSD	GDSC	10.658	Down-regulation
Atypical_PIKK_ATR_ATR_ST	O75717	WDHD1	Q13535	ATR	S893	D895V	895	Missense	proximal	2	no	9.749	10.993	EPSD	GDSC;CCLE	10.658	Gain
Atypical_PIKK_ATR_ATR_ST	O75717	WDHD1	Q13535	ATR	S907	R910*	910	Missense	distal	3	no	16.617	15.580	EPSD	GDSC	10.658	Down-regulation
Atypical_PIKK_ATR_ATR_ST	O75717	WDHD1	Q13535	ATR	S926	S926P	926	Missense	central	0	yes	12.124	0.000	EPSD	GDSC;CCLE	10.658	Loss
Atypical_PIKK_ATR_ATR_ST	O75717	WDHD1	Q13535	ATR	S984	R982T	982	Missense	proximal	-2	no	13.455	13.348	EPSD	GDSC;CCLE	10.658	Down-regulation
Atypical_PIKK_ATR_ATR_ST	P49006	MARCKSL1	Q13535	ATR	T148	Q141E	141	Missense	distal	-7	no	10.983	11.029	EPSD	GDSC;CCLE	10.658	Up-regulation
Atypical_PIKK_ATR_ATR_ST	P49006	MARCKSL1	Q13535	ATR	T148	G143E	143	Missense	distal	-5	no	10.983	10.883	EPSD	GDSC;CCLE	10.658	Down-regulation
Atypical_PIKK_ATR_ATR_ST	P49006	MARCKSL1	Q13535	ATR	T178	S184G	184	Missense	distal	6	no	11.017	10.775	EPSD	GDSC;CCLE	10.658	Down-regulation
STE_STE20_SLK_STK10_ST	P35241	RDX	O94804	STK10	T564	K563N	563	Missense	proximal	-1	no	8.215	7.853	PhosphoSitePlus	GDSC;CCLE	2.434	Down-regulation
STE_STE20_SLK_STK10_ST	P15311	EZR	O94804	STK10	T497	A501T	501	Missense	distal	4	no	3.307	3.308	EPSD	GDSC;CCLE	2.434	Up-regulation
STE_STE20_SLK_STK10_ST	P26038	MSN	O94804	STK10	T66	V70L	70	Missense	distal	4	no	2.677	2.687	EPSD	GDSC	2.434	Up-regulation
STE_STE20_SLK_STK10_ST	P26038	MSN	O94804	STK10	S74	V70L	70	Missense	distal	-4	no	3.891	3.814	EPSD	GDSC	2.434	Down-regulation
TK_Abl_ABL2_Y	P04040	CAT	P42684	ABL2	Y386	Y379F	379	Missense	distal	-7	no	33.162	29.451	EPSD;PhosphoSitePlus	GDSC;CCLE	19.113	Down-regulation
TK_Abl_ABL2_Y	P17931	LGALS3	P42684	ABL2	Y79	G85D	85	Missense	distal	6	no	38.241	38.325	EPSD;PhosphoSitePlus	GDSC;CCLE	19.113	Up-regulation
TK_Abl_ABL2_Y	P17931	LGALS3	P42684	ABL2	Y79	G72R	72	Missense	distal	-7	no	38.241	39.960	EPSD;PhosphoSitePlus	GDSC;CCLE	19.113	Up-regulation
TK_Abl_ABL2_Y	P09619	PDGFRB	P42684	ABL2	Y686	I679N	679	Missense	distal	-7	no	32.293	31.505	PhosphoSitePlus	GDSC	19.113	Down-regulation
TK_Abl_ABL2_Y	P09619	PDGFRB	P42684	ABL2	Y771	P774L	774	Missense	distal	3	no	20.077	11.769	EPSD	GDSC;CCLE	19.113	Loss
TK_Abl_ABL2_Y	P09619	PDGFRB	P42684	ABL2	Y934	M937V	937	Missense	distal	3	no	26.698	31.524	EPSD	GDSC;CCLE	19.113	Up-regulation
TKL_LISK_LIMK_LIMK1_ST	P23528	CFL1	P53667	LIMK1	S3	G4D	4	Missense	proximal	1	no	3.972	3.194	PhosphoSitePlus	GDSC	-0.776	Down-regulation
TK_Src_SrcB_HCK_Y	P11274	BCR	P08631	HCK	Y177	F176L	176	Missense	proximal	-1	no	11.230	11.180	PhosphoSitePlus	GDSC;CCLE	7.597	Down-regulation
TK_Src_SrcB_HCK_Y	Q92556	ELMO1	P08631	HCK	Y18	D25A	25	Missense	distal	7	no	10.836	10.971	EPSD;PhosphoSitePlus	GDSC;CCLE	7.597	Up-regulation
TK_Src_SrcB_HCK_Y	P08631	HCK	P08631	HCK	Y51	P46A	46	Missense	distal	-5	no	11.142	11.077	EPSD	GDSC	7.597	Down-regulation
TK_Src_SrcB_HCK_Y	P42229	STAT5A	P08631	HCK	Y694	P697L	697	Missense	distal	3	no	11.334	10.976	PhosphoSitePlus	GDSC	7.597	Down-regulation
TK_Src_SrcB_HCK_Y	Q13444	ADAM15	P08631	HCK	Y715	A719P	719	Missense	distal	4	no	11.829	10.326	PhosphoSitePlus	GDSC	7.597	Down-regulation
TK_Src_SrcB_HCK_Y	Q13444	ADAM15	P08631	HCK	Y715	H722R	722	Missense	distal	7	no	11.829	11.878	PhosphoSitePlus	GDSC;CCLE	7.597	Up-regulation
TK_Src_SrcB_HCK_Y	Q13444	ADAM15	P08631	HCK	Y715	Y717S	717	Missense	proximal	2	no	11.829	12.251	PhosphoSitePlus	GDSC;CCLE	7.597	Up-regulation
TK_Src_SrcB_HCK_Y	Q13444	ADAM15	P08631	HCK	Y715	R718C	718	Missense	distal	3	no	11.829	10.283	PhosphoSitePlus	GDSC;CCLE	7.597	Down-regulation
TK_Src_SrcB_HCK_Y	Q13444	ADAM15	P08631	HCK	Y735	P742L	742	Missense	distal	7	no	10.220	10.206	EPSD	GDSC;CCLE	7.597	Down-regulation
TK_Src_SrcB_HCK_Y	Q9UHD2	TBK1	P08631	HCK	Y354	R357*	357	Missense	distal	3	no	10.303	8.728	PhosphoSitePlus;EPSD	GDSC	7.597	Down-regulation
TK_Src_SrcB_HCK_Y	Q9UHD2	TBK1	P08631	HCK	Y354	R358C	358	Missense	distal	4	no	10.303	8.399	PhosphoSitePlus;EPSD	GDSC;CCLE	7.597	Down-regulation
TKL_MLK_MLK_MAP3K11_ST	P46734	MAP2K3	Q16584	MAP3K11	S218	V216G	216	Missense	proximal	-2	no	4.316	4.364	PhosphoSitePlus;EPSD	GDSC;CCLE	1.264	Up-regulation
TKL_MLK_MLK_MAP3K11_ST	P46734	MAP2K3	Q16584	MAP3K11	S218	D217E	217	Missense	proximal	-1	no	4.316	4.214	PhosphoSitePlus;EPSD	GDSC;CCLE	1.264	Down-regulation
TKL_MLK_MLK_MAP3K11_ST	P46734	MAP2K3	Q16584	MAP3K11	T222	V216G	216	Missense	distal	-6	no	4.657	4.490	EPSD;PhosphoSitePlus	GDSC;CCLE	1.264	Down-regulation
TKL_MLK_MLK_MAP3K11_ST	P46734	MAP2K3	Q16584	MAP3K11	T222	D217E	217	Missense	distal	-5	no	4.657	4.658	EPSD;PhosphoSitePlus	GDSC;CCLE	1.264	Up-regulation
TKL_MLK_MLK_MAP3K11_ST	P46734	MAP2K3	Q16584	MAP3K11	T222	K228R	228	Missense	distal	6	no	4.657	4.696	EPSD;PhosphoSitePlus	GDSC;CCLE	1.264	Up-regulation
TKL_MLK_MLK_MAP3K11_ST	Q13526	PIN1	Q16584	MAP3K11	S108	D102E	102	Missense	distal	-6	no	2.412	2.432	EPSD	GDSC;CCLE	1.264	Up-regulation
TKL_MLK_MLK_MAP3K11_ST	Q13526	PIN1	Q16584	MAP3K11	S138	R142Q	142	Missense	distal	4	no	3.911	3.913	PhosphoSitePlus	GDSC	1.264	Up-regulation
TKL_MLK_MLK_MAP3K11_ST	Q13526	PIN1	Q16584	MAP3K11	T152	G155S	155	Missense	distal	3	no	1.711	1.365	EPSD	GDSC	1.264	Down-regulation
TKL_MLK_MLK_MAP3K11_ST	Q13526	PIN1	Q16584	MAP3K11	T152	H157Q	157	Missense	distal	5	no	1.711	1.708	EPSD	GDSC;CCLE	1.264	Down-regulation
TKL_MLK_MLK_MAP3K11_ST	P45985	MAP2K4	Q16584	MAP3K11	S80	S80I	80	Missense	central	0	yes	1.301	0.000	EPSD	GDSC;CCLE	1.264	Loss
Atypical_PDHK_PDHK_PDK3_ST	P08559	PDHA1	Q15120	PDK3	T286	Q285R	285	Missense	proximal	-1	no	1.908	1.952	EPSD	GDSC;CCLE	1.746	Up-regulation
Atypical_PDHK_PDHK_PDK3_ST	P29803	PDHA2	Q15120	PDK3	T231	E232K	232	Missense	proximal	1	no	2.638	2.386	EPSD	GDSC;CCLE	1.746	Down-regulation
Atypical_PDHK_PDHK_PDK3_ST	P29803	PDHA2	Q15120	PDK3	T284	P277H	277	Missense	distal	-7	no	1.777	1.787	EPSD	GDSC;CCLE	1.746	Up-regulation
Atypical_PDHK_PDHK_PDK3_ST	P29803	PDHA2	Q15120	PDK3	S291	V297F	297	Missense	distal	6	no	10.124	10.122	EPSD;PhosphoSitePlus	GDSC;CCLE	1.746	Down-regulation
Atypical_PDHK_PDHK_PDK3_ST	P29803	PDHA2	Q15120	PDK3	S293	V297F	297	Missense	distal	4	no	2.409	2.406	EPSD	GDSC;CCLE	1.746	Down-regulation
Atypical_PDHK_PDHK_PDK3_ST	P29803	PDHA2	Q15120	PDK3	S298	V297F	297	Missense	proximal	-1	no	9.541	9.478	PhosphoSitePlus;EPSD	GDSC;CCLE	1.746	Down-regulation
AGC_DMPK_ROCK_ROCK2_ST	P19634	SLC9A1	O75116	ROCK2	T653	R647L	647	Missense	distal	-6	no	28.935	26.076	PhosphoSitePlus	GDSC;CCLE	20.789	Down-regulation
AGC_DMPK_ROCK_ROCK2_ST	P19634	SLC9A1	O75116	ROCK2	S703	A707V	707	Missense	distal	4	no	20.803	20.932	EPSD	GDSC;CCLE	20.789	Up-regulation
AGC_DMPK_ROCK_ROCK2_ST	P56817	BACE1	O75116	ROCK2	T47	P54T	54	Missense	distal	7	no	22.784	23.058	EPSD	GDSC	20.789	Up-regulation
AGC_DMPK_ROCK_ROCK2_ST	P56817	BACE1	O75116	ROCK2	S59	P54T	54	Missense	distal	-5	no	23.679	24.568	EPSD	GDSC	20.789	Up-regulation
AGC_DMPK_ROCK_ROCK2_ST	P56817	BACE1	O75116	ROCK2	S498	D492A	492	Missense	distal	-6	no	27.416	29.468	PhosphoSitePlus	GDSC	20.789	Up-regulation
AGC_DMPK_ROCK_ROCK2_ST	Q92673	SORL1	O75116	ROCK2	S1987	L1993F	1993	Missense	distal	6	no	24.100	24.195	EPSD	GDSC	20.789	Up-regulation
AGC_DMPK_ROCK_ROCK2_ST	Q92673	SORL1	O75116	ROCK2	S2179	G2182V	2182	Missense	distal	3	no	21.926	22.024	EPSD	GDSC;CCLE	20.789	Up-regulation
AGC_DMPK_ROCK_ROCK2_ST	Q16555	DPYSL2	O75116	ROCK2	S85	Q91K	91	Missense	distal	6	no	27.245	26.676	EPSD	GDSC;CCLE	20.789	Down-regulation
AGC_DMPK_ROCK_ROCK2_ST	Q16555	DPYSL2	O75116	ROCK2	T554	A560V	560	Missense	distal	6	no	20.455	20.835	EPSD	GDSC	20.789	Gain
AGC_DMPK_ROCK_ROCK2_ST	Q16555	DPYSL2	O75116	ROCK2	T555	A560V	560	Missense	distal	5	no	39.349	40.457	PhosphoSitePlus	GDSC	20.789	Up-regulation
AGC_DMPK_ROCK_ROCK2_ST	O75116	ROCK2	O75116	ROCK2	T16	P18Q	18	Missense	proximal	2	no	23.398	23.301	EPSD	GDSC;CCLE	20.789	Down-regulation
AGC_DMPK_ROCK_ROCK2_ST	O75116	ROCK2	O75116	ROCK2	S1379	R1380*	1380	Missense	proximal	1	no	39.468	39.491	EPSD;PhosphoSitePlus	GDSC	20.789	Up-regulation
AGC_DMPK_ROCK_ROCK2_ST	P98082	DAB2	O75116	ROCK2	S24	K28R	28	Missense	distal	4	no	22.148	23.399	EPSD	GDSC;CCLE	20.789	Up-regulation
AGC_DMPK_ROCK_ROCK2_ST	P98082	DAB2	O75116	ROCK2	S723	P719H	719	Missense	distal	-4	no	30.116	29.675	PhosphoSitePlus	GDSC	20.789	Down-regulation
AGC_DMPK_ROCK_ROCK2_ST	Q99962	SH3GL2	O75116	ROCK2	S262	E264Q	264	Missense	proximal	2	no	23.343	23.335	EPSD	GDSC;CCLE	20.789	Down-regulation
AGC_DMPK_ROCK_ROCK2_ST	P05067	APP	O75116	ROCK2	S679	H684Y	684	Missense	distal	5	no	23.926	24.467	EPSD	GDSC	20.789	Up-regulation
AGC_DMPK_ROCK_ROCK2_ST	P05067	APP	O75116	ROCK2	S679	R676*	676	Missense	distal	-3	no	23.926	10.489	EPSD	GDSC	20.789	Loss
AGC_DMPK_ROCK_ROCK2_ST	P05067	APP	O75116	ROCK2	T729	G734D	734	Missense	distal	5	no	32.174	32.364	EPSD	GDSC;CCLE	20.789	Up-regulation
AGC_DMPK_ROCK_ROCK2_ST	P05067	APP	O75116	ROCK2	S730	G734D	734	Missense	distal	4	no	28.131	28.902	EPSD	GDSC;CCLE	20.789	Up-regulation
AGC_DMPK_ROCK_ROCK2_ST	Q15417	CNN3	O75116	ROCK2	S259	R265Q	265	Missense	distal	6	no	23.547	24.136	EPSD	GDSC;CCLE	20.789	Up-regulation
AGC_DMPK_ROCK_ROCK2_ST	Q15417	CNN3	O75116	ROCK2	S259	Q266R	266	Missense	distal	7	no	23.547	22.906	EPSD	GDSC;CCLE	20.789	Down-regulation
AGC_DMPK_ROCK_ROCK2_ST	Q15417	CNN3	O75116	ROCK2	S323	Y316C	316	Missense	distal	-7	no	23.116	22.654	EPSD	GDSC;CCLE	20.789	Down-regulation
AGC_DMPK_ROCK_ROCK2_ST	Q96C90	PPP1R14B	O75116	ROCK2	T57	Q53E	53	Missense	distal	-4	no	31.042	30.013	PhosphoSitePlus	GDSC;CCLE	20.789	Down-regulation
AGC_DMPK_ROCK_ROCK2_ST	Q96C90	PPP1R14B	O75116	ROCK2	S142	G137S	137	Missense	distal	-5	no	30.324	29.498	EPSD	GDSC;CCLE	20.789	Down-regulation
AGC_DMPK_ROCK_ROCK2_ST	Q96C90	PPP1R14B	O75116	ROCK2	S142	R136Q	136	Missense	distal	-6	no	30.324	29.469	EPSD	GDSC;CCLE	20.789	Down-regulation
AGC_DMPK_ROCK_ROCK2_ST	Q96C90	PPP1R14B	O75116	ROCK2	T143	G137S	137	Missense	distal	-6	no	24.071	21.832	EPSD	GDSC;CCLE	20.789	Down-regulation
AGC_DMPK_ROCK_ROCK2_ST	Q96C90	PPP1R14B	O75116	ROCK2	T143	R136Q	136	Missense	distal	-7	no	24.071	24.575	EPSD	GDSC;CCLE	20.789	Up-regulation
STE_STE-Unique_MAP3K14_ST	O15111	CHUK	Q99558	MAP3K14	S123	S126C	126	Missense	distal	3	no	241.494	239.202	EPSD	GDSC	201.043	Down-regulation
STE_STE-Unique_MAP3K14_ST	O15111	CHUK	Q99558	MAP3K14	S176	Q174H	174	Missense	proximal	-2	no	389.213	375.321	PhosphoSitePlus;EPSD	GDSC;CCLE	201.043	Down-regulation
STE_STE-Unique_MAP3K14_ST	O15111	CHUK	Q99558	MAP3K14	S180	Q174H	174	Missense	distal	-6	no	352.976	326.824	EPSD;PhosphoSitePlus	GDSC;CCLE	201.043	Down-regulation
STE_STE-Unique_MAP3K14_ST	O15111	CHUK	Q99558	MAP3K14	S581	E585A	585	Missense	distal	4	no	225.742	196.782	EPSD	GDSC;CCLE	201.043	Loss
STE_STE-Unique_MAP3K14_ST	O14920	IKBKB	Q99558	MAP3K14	S239	D242N	242	Missense	distal	3	no	204.532	203.203	EPSD	GDSC;CCLE	201.043	Down-regulation
STE_STE-Unique_MAP3K14_ST	O14920	IKBKB	Q99558	MAP3K14	T501	S507*	507	Missense	distal	6	no	236.677	220.417	EPSD	GDSC	201.043	Down-regulation
STE_STE-Unique_MAP3K14_ST	O14920	IKBKB	Q99558	MAP3K14	T583	M590I	590	Missense	distal	7	no	216.886	213.210	EPSD	GDSC;CCLE	201.043	Down-regulation
STE_STE-Unique_MAP3K14_ST	O14920	IKBKB	Q99558	MAP3K14	S587	M590I	590	Missense	distal	3	no	249.693	247.763	EPSD	GDSC;CCLE	201.043	Down-regulation
STE_STE-Unique_MAP3K14_ST	O14920	IKBKB	Q99558	MAP3K14	S692	G685W	685	Missense	distal	-7	no	222.696	212.750	EPSD	GDSC;CCLE	201.043	Down-regulation
STE_STE-Unique_MAP3K14_ST	O14920	IKBKB	Q99558	MAP3K14	S733	F734L	734	Missense	proximal	1	no	228.964	225.636	EPSD	GDSC	201.043	Down-regulation
AGC_RSK_RSKp70_RPS6KB1_ST	Q9BYV9	BACH2	P23443	RPS6KB1	S521	Y526C	526	Missense	distal	5	no	40.367	40.934	PhosphoSitePlus	GDSC	24.279	Up-regulation
AGC_RSK_RSKp70_RPS6KB1_ST	Q9BYV9	BACH2	P23443	RPS6KB1	S525	Y526C	526	Missense	proximal	1	no	30.986	31.359	EPSD	GDSC	24.279	Up-regulation
AGC_RSK_RSKp70_RPS6KB1_ST	Q9BYV9	BACH2	P23443	RPS6KB1	S527	Y526C	526	Missense	proximal	-1	no	26.399	26.474	EPSD	GDSC	24.279	Up-regulation
AGC_RSK_RSKp70_RPS6KB1_ST	Q9BYV9	BACH2	P23443	RPS6KB1	S527	G534R	534	Missense	distal	7	no	26.399	26.243	EPSD	GDSC;CCLE	24.279	Down-regulation
AGC_RSK_RSKp70_RPS6KB1_ST	P35568	IRS1	P23443	RPS6KB1	S270	R267C	267	Missense	distal	-3	no	44.958	35.409	EPSD;PhosphoSitePlus	GDSC;CCLE	24.279	Down-regulation
AGC_RSK_RSKp70_RPS6KB1_ST	P35568	IRS1	P23443	RPS6KB1	S272	R267C	267	Missense	distal	-5	no	27.405	18.172	EPSD	GDSC;CCLE	24.279	Loss
AGC_RSK_RSKp70_RPS6KB1_ST	P35568	IRS1	P23443	RPS6KB1	S362	R364W	364	Missense	proximal	2	no	27.313	24.621	EPSD	GDSC	24.279	Down-regulation
AGC_RSK_RSKp70_RPS6KB1_ST	P35568	IRS1	P23443	RPS6KB1	S362	P368A	368	Missense	distal	6	no	27.313	27.168	EPSD	GDSC;CCLE	24.279	Down-regulation
AGC_RSK_RSKp70_RPS6KB1_ST	P35568	IRS1	P23443	RPS6KB1	S372	H371R	371	Missense	proximal	-1	no	31.118	31.100	EPSD	GDSC	24.279	Down-regulation
AGC_RSK_RSKp70_RPS6KB1_ST	P35568	IRS1	P23443	RPS6KB1	S372	P368A	368	Missense	distal	-4	no	31.118	31.660	EPSD	GDSC;CCLE	24.279	Up-regulation
AGC_RSK_RSKp70_RPS6KB1_ST	P35568	IRS1	P23443	RPS6KB1	S372	P376L	376	Missense	distal	4	no	31.118	31.604	EPSD	GDSC;CCLE	24.279	Up-regulation
AGC_RSK_RSKp70_RPS6KB1_ST	P35568	IRS1	P23443	RPS6KB1	S374	H371R	371	Missense	distal	-3	no	23.203	26.691	EPSD	GDSC	24.279	Gain
AGC_RSK_RSKp70_RPS6KB1_ST	P35568	IRS1	P23443	RPS6KB1	S374	P376L	376	Missense	proximal	2	no	23.203	24.381	EPSD	GDSC;CCLE	24.279	Gain
AGC_RSK_RSKp70_RPS6KB1_ST	P35568	IRS1	P23443	RPS6KB1	S391	A386S	386	Missense	distal	-5	no	27.826	30.028	EPSD	GDSC;CCLE	24.279	Up-regulation
AGC_RSK_RSKp70_RPS6KB1_ST	P35568	IRS1	P23443	RPS6KB1	S415	R411*	411	Missense	distal	-4	no	39.075	37.027	EPSD	GDSC	24.279	Down-regulation
AGC_RSK_RSKp70_RPS6KB1_ST	P35568	IRS1	P23443	RPS6KB1	S603	G597E	597	Missense	distal	-6	no	29.002	28.984	EPSD	GDSC	24.279	Down-regulation
AGC_RSK_RSKp70_RPS6KB1_ST	P35568	IRS1	P23443	RPS6KB1	S604	G597E	597	Missense	distal	-7	no	24.894	24.669	EPSD	GDSC	24.279	Down-regulation
AGC_RSK_RSKp70_RPS6KB1_ST	P35568	IRS1	P23443	RPS6KB1	S636	A642S	642	Missense	distal	6	no	36.942	38.061	PhosphoSitePlus;EPSD	GDSC;CCLE	24.279	Up-regulation
AGC_RSK_RSKp70_RPS6KB1_ST	P35568	IRS1	P23443	RPS6KB1	S639	A642S	642	Missense	distal	3	no	35.291	37.740	EPSD	GDSC;CCLE	24.279	Up-regulation
AGC_RSK_RSKp70_RPS6KB1_ST	P35568	IRS1	P23443	RPS6KB1	S1101	R1096G	1096	Missense	distal	-5	no	49.169	41.925	EPSD;PhosphoSitePlus	GDSC;CCLE	24.279	Down-regulation
AGC_RSK_RSKp70_RPS6KB1_ST	P35568	IRS1	P23443	RPS6KB1	T1103	R1096G	1096	Missense	distal	-7	no	30.220	30.355	EPSD	GDSC;CCLE	24.279	Up-regulation
AGC_RSK_RSKp70_RPS6KB1_ST	P35568	IRS1	P23443	RPS6KB1	S1217	S1218P	1218	Missense	proximal	1	no	23.620	24.637	EPSD	GDSC	24.279	Gain
AGC_RSK_RSKp70_RPS6KB1_ST	Q15633	TARBP2	P23443	RPS6KB1	S283	C282Y	282	Missense	proximal	-1	no	39.175	39.099	PhosphoSitePlus	GDSC	24.279	Down-regulation
AGC_RSK_RSKp70_RPS6KB1_ST	Q15633	TARBP2	P23443	RPS6KB1	S283	S281R	281	Missense	proximal	-2	no	39.175	39.820	PhosphoSitePlus	GDSC	24.279	Up-regulation
AGC_RSK_RSKp70_RPS6KB1_ST	P42345	MTOR	P23443	RPS6KB1	S831	M825I	825	Missense	distal	-6	no	25.316	25.346	EPSD	GDSC;CCLE	24.279	Up-regulation
AGC_RSK_RSKp70_RPS6KB1_ST	P42345	MTOR	P23443	RPS6KB1	S1893	R1896*	1896	Missense	distal	3	no	24.886	23.041	EPSD	GDSC	24.279	Loss
AGC_RSK_RSKp70_RPS6KB1_ST	P42345	MTOR	P23443	RPS6KB1	S1893	L1894V	1894	Missense	proximal	1	no	24.886	24.455	EPSD	GDSC;CCLE	24.279	Down-regulation
AGC_RSK_RSKp70_RPS6KB1_ST	P42345	MTOR	P23443	RPS6KB1	S2069	Q2072*	2072	Missense	distal	3	no	29.073	28.555	EPSD	GDSC	24.279	Down-regulation
AGC_RSK_RSKp70_RPS6KB1_ST	P42345	MTOR	P23443	RPS6KB1	S2514	T2509A	2509	Missense	distal	-5	no	25.147	25.011	EPSD	GDSC;CCLE	24.279	Down-regulation
AGC_RSK_RSKp70_RPS6KB1_ST	Q06787	FMR1	P23443	RPS6KB1	S191	K195T	195	Missense	distal	4	no	30.707	30.242	EPSD	GDSC;CCLE	24.279	Down-regulation
AGC_RSK_RSKp70_RPS6KB1_ST	Q9UN36	NDRG2	P23443	RPS6KB1	S344	R343W	343	Missense	proximal	-1	no	27.128	27.181	EPSD	GDSC;CCLE	24.279	Up-regulation
AGC_RSK_RSKp70_RPS6KB1_ST	Q9UN36	NDRG2	P23443	RPS6KB1	S344	Q351*	351	Missense	distal	7	no	27.128	26.022	EPSD	GDSC	24.279	Down-regulation
AGC_RSK_RSKp70_RPS6KB1_ST	Q9UN36	NDRG2	P23443	RPS6KB1	S346	R343W	343	Missense	distal	-3	no	30.746	15.731	EPSD	GDSC;CCLE	24.279	Loss
AGC_RSK_RSKp70_RPS6KB1_ST	Q9UN36	NDRG2	P23443	RPS6KB1	S346	Q351*	351	Missense	distal	5	no	30.746	28.258	EPSD	GDSC	24.279	Down-regulation
AGC_RSK_RSKp70_RPS6KB1_ST	Q9UN36	NDRG2	P23443	RPS6KB1	T348	R343W	343	Missense	distal	-5	no	34.565	22.602	EPSD	GDSC;CCLE	24.279	Loss
AGC_RSK_RSKp70_RPS6KB1_ST	Q9UN36	NDRG2	P23443	RPS6KB1	T348	Q351*	351	Missense	distal	3	no	34.565	34.047	EPSD	GDSC	24.279	Down-regulation
AGC_RSK_RSKp70_RPS6KB1_ST	Q9UN36	NDRG2	P23443	RPS6KB1	S350	R343W	343	Missense	distal	-7	no	38.747	38.951	PhosphoSitePlus;EPSD	GDSC;CCLE	24.279	Up-regulation
AGC_RSK_RSKp70_RPS6KB1_ST	Q9UN36	NDRG2	P23443	RPS6KB1	S350	Q351*	351	Missense	proximal	1	no	38.747	39.112	PhosphoSitePlus;EPSD	GDSC	24.279	Up-regulation
AGC_RSK_RSKp70_RPS6KB1_ST	Q9UN36	NDRG2	P23443	RPS6KB1	S355	Q351*	351	Missense	distal	-4	no	27.881	27.854	EPSD	GDSC	24.279	Down-regulation
AGC_RSK_RSKp70_RPS6KB1_ST	P62753	RPS6	P23443	RPS6KB1	S235	S242F	242	Missense	distal	7	no	33.709	31.829	EPSD;PhosphoSitePlus	GDSC	24.279	Down-regulation
AGC_RSK_RSKp70_RPS6KB1_ST	P62753	RPS6	P23443	RPS6KB1	S236	S242F	242	Missense	distal	6	no	44.462	42.448	EPSD;PhosphoSitePlus	GDSC	24.279	Down-regulation
AGC_RSK_RSKp70_RPS6KB1_ST	P62753	RPS6	P23443	RPS6KB1	S240	S242F	242	Missense	proximal	2	no	32.959	27.760	EPSD;PhosphoSitePlus	GDSC	24.279	Down-regulation
AGC_RSK_RSKp70_RPS6KB1_ST	P62753	RPS6	P23443	RPS6KB1	T241	S242F	242	Missense	proximal	1	no	36.295	37.843	EPSD	GDSC	24.279	Up-regulation
AGC_RSK_RSKp70_RPS6KB1_ST	P62753	RPS6	P23443	RPS6KB1	S242	S242F	242	Missense	central	0	yes	28.184	0.000	EPSD	GDSC	24.279	Loss
AGC_RSK_RSKp70_RPS6KB1_ST	P62753	RPS6	P23443	RPS6KB1	S244	S242F	242	Missense	proximal	-2	no	30.542	32.409	PhosphoSitePlus;EPSD	GDSC	24.279	Up-regulation
AGC_RSK_RSKp70_RPS6KB1_ST	P49841	GSK3B	P23443	RPS6KB1	T7	T8P	8	Missense	proximal	1	no	27.025	27.305	EPSD	GDSC	24.279	Up-regulation
AGC_RSK_RSKp70_RPS6KB1_ST	P49841	GSK3B	P23443	RPS6KB1	S9	T8P	8	Missense	proximal	-1	no	43.554	43.623	PhosphoSitePlus	GDSC	24.279	Up-regulation
AGC_RSK_RSKp70_RPS6KB1_ST	P49841	GSK3B	P23443	RPS6KB1	S13	T8P	8	Missense	distal	-5	no	27.467	26.595	EPSD	GDSC	24.279	Down-regulation
AGC_RSK_RSKp70_RPS6KB1_ST	Q53EL6	PDCD4	P23443	RPS6KB1	S67	R69W	69	Missense	proximal	2	no	38.492	35.800	PhosphoSitePlus;EPSD	GDSC	24.279	Down-regulation
AGC_RSK_RSKp70_RPS6KB1_ST	Q53EL6	PDCD4	P23443	RPS6KB1	S76	S80I	80	Missense	distal	4	no	35.747	34.558	EPSD	GDSC;CCLE	24.279	Down-regulation
AGC_RSK_RSKp70_RPS6KB1_ST	Q53EL6	PDCD4	P23443	RPS6KB1	S76	R69W	69	Missense	distal	-7	no	35.747	35.951	EPSD	GDSC	24.279	Up-regulation
AGC_RSK_RSKp70_RPS6KB1_ST	Q53EL6	PDCD4	P23443	RPS6KB1	S313	G307R	307	Missense	distal	-6	no	25.958	25.928	EPSD	GDSC	24.279	Down-regulation
AGC_RSK_RSKp70_RPS6KB1_ST	Q53EL6	PDCD4	P23443	RPS6KB1	S345	H349Q	349	Missense	distal	4	no	30.675	30.698	EPSD	GDSC;CCLE	24.279	Up-regulation
AGC_RSK_RSKp70_RPS6KB1_ST	Q53EL6	PDCD4	P23443	RPS6KB1	S345	S341F	341	Missense	distal	-4	no	30.675	28.047	EPSD	GDSC;CCLE	24.279	Down-regulation
AGC_RSK_RSKp70_RPS6KB1_ST	Q53EL6	PDCD4	P23443	RPS6KB1	S345	Y338C	338	Missense	distal	-7	no	30.675	30.570	EPSD	GDSC	24.279	Down-regulation
AGC_RSK_RSKp70_RPS6KB1_ST	P10636	MAPT	P23443	RPS6KB1	T17	T17M	17	Missense	central	0	yes	26.536	0.000	EPSD	GDSC	24.279	Loss
AGC_RSK_RSKp70_RPS6KB1_ST	P10636	MAPT	P23443	RPS6KB1	S56	Q49H	49	Missense	distal	-7	no	25.475	25.460	EPSD	GDSC	24.279	Down-regulation
AGC_RSK_RSKp70_RPS6KB1_ST	P10636	MAPT	P23443	RPS6KB1	S171	D177V	177	Missense	distal	6	no	32.927	33.020	EPSD	GDSC	24.279	Up-regulation
AGC_RSK_RSKp70_RPS6KB1_ST	P10636	MAPT	P23443	RPS6KB1	S214	V218G	218	Missense	distal	4	no	27.785	27.405	PhosphoSitePlus;EPSD	GDSC	24.279	Down-regulation
AGC_RSK_RSKp70_RPS6KB1_ST	P10636	MAPT	P23443	RPS6KB1	S341	P340L	340	Missense	proximal	-1	no	38.788	38.741	EPSD	GDSC;CCLE	24.279	Down-regulation
AGC_RSK_RSKp70_RPS6KB1_ST	P10636	MAPT	P23443	RPS6KB1	S341	G339S	339	Missense	proximal	-2	no	38.788	39.009	EPSD	GDSC;CCLE	24.279	Up-regulation
AGC_RSK_RSKp70_RPS6KB1_ST	P10636	MAPT	P23443	RPS6KB1	S641	V635I	635	Missense	distal	-6	no	26.786	26.771	EPSD	GDSC	24.279	Down-regulation
AGC_RSK_RSKp70_RPS6KB1_ST	Q8TB45	DEPTOR	P23443	RPS6KB1	S15	A22G	22	Missense	distal	7	no	25.281	25.216	EPSD	GDSC	24.279	Down-regulation
AGC_RSK_RSKp70_RPS6KB1_ST	Q8TB45	DEPTOR	P23443	RPS6KB1	T59	F64S	64	Missense	distal	5	no	33.863	39.225	EPSD	GDSC;CCLE	24.279	Up-regulation
AGC_RSK_RSKp70_RPS6KB1_ST	Q8TB45	DEPTOR	P23443	RPS6KB1	S235	Q239K	239	Missense	distal	4	no	24.228	25.060	EPSD	GDSC;CCLE	24.279	Gain
AGC_RSK_RSKp70_RPS6KB1_ST	Q8TB45	DEPTOR	P23443	RPS6KB1	S237	Q239K	239	Missense	proximal	2	no	22.918	25.675	EPSD	GDSC;CCLE	24.279	Gain
AGC_RSK_RSKp70_RPS6KB1_ST	Q8TB45	DEPTOR	P23443	RPS6KB1	S238	H242N	242	Missense	distal	4	no	28.362	28.431	EPSD	GDSC	24.279	Up-regulation
AGC_RSK_RSKp70_RPS6KB1_ST	Q8TB45	DEPTOR	P23443	RPS6KB1	S238	Q239K	239	Missense	proximal	1	no	28.362	27.409	EPSD	GDSC;CCLE	24.279	Down-regulation
AGC_RSK_RSKp70_RPS6KB1_ST	O00418	EEF2K	P23443	RPS6KB1	S66	Y69H	69	Missense	distal	3	no	25.313	25.030	EPSD	GDSC;CCLE	24.279	Down-regulation
AGC_RSK_RSKp70_RPS6KB1_ST	O00418	EEF2K	P23443	RPS6KB1	S71	Y69H	69	Missense	proximal	-2	no	34.356	33.987	EPSD	GDSC;CCLE	24.279	Down-regulation
AGC_RSK_RSKp70_RPS6KB1_ST	O00418	EEF2K	P23443	RPS6KB1	S435	S438N	438	Missense	distal	3	no	26.043	25.205	EPSD	GDSC;CCLE	24.279	Down-regulation
AGC_RSK_RSKp70_RPS6KB1_ST	O00418	EEF2K	P23443	RPS6KB1	S435	E434*	434	Missense	proximal	-1	no	26.043	26.150	EPSD	GDSC	24.279	Up-regulation
AGC_RSK_RSKp70_RPS6KB1_ST	O00418	EEF2K	P23443	RPS6KB1	S438	S438N	438	Missense	central	0	yes	28.507	0.000	EPSD	GDSC;CCLE	24.279	Loss
AGC_RSK_RSKp70_RPS6KB1_ST	O00418	EEF2K	P23443	RPS6KB1	S438	E434*	434	Missense	distal	-4	no	28.507	26.905	EPSD	GDSC	24.279	Down-regulation
AGC_RSK_RSKp70_RPS6KB1_ST	O00418	EEF2K	P23443	RPS6KB1	S445	G449S	449	Missense	distal	4	no	28.174	29.767	EPSD	GDSC	24.279	Up-regulation
AGC_RSK_RSKp70_RPS6KB1_ST	O00418	EEF2K	P23443	RPS6KB1	S445	S438N	438	Missense	distal	-7	no	28.174	28.247	EPSD	GDSC;CCLE	24.279	Up-regulation
AGC_RSK_RSKp70_RPS6KB1_ST	O00418	EEF2K	P23443	RPS6KB1	S492	N490T	490	Missense	proximal	-2	no	28.251	27.646	EPSD	GDSC	24.279	Down-regulation
AGC_RSK_RSKp70_RPS6KB1_ST	O00418	EEF2K	P23443	RPS6KB1	S492	H495P	495	Missense	distal	3	no	28.251	27.671	EPSD	GDSC	24.279	Down-regulation
AGC_RSK_RSKp70_RPS6KB1_ST	O00418	EEF2K	P23443	RPS6KB1	S492	S491P	491	Missense	proximal	-1	no	28.251	28.347	EPSD	GDSC	24.279	Up-regulation
AGC_RSK_RSKp70_RPS6KB1_ST	P03372	ESR1	P23443	RPS6KB1	S154	R151H	151	Missense	distal	-3	no	24.680	21.192	EPSD	GDSC	24.279	Loss
AGC_RSK_RSKp70_RPS6KB1_ST	P03372	ESR1	P23443	RPS6KB1	S154	G160S	160	Missense	distal	6	no	24.680	24.514	EPSD	GDSC	24.279	Down-regulation
AGC_RSK_RSKp70_RPS6KB1_ST	P03372	ESR1	P23443	RPS6KB1	S167	G160S	160	Missense	distal	-7	no	39.842	39.665	PhosphoSitePlus	GDSC	24.279	Down-regulation
AGC_RSK_RSKp70_RPS6KB1_ST	P03372	ESR1	P23443	RPS6KB1	S167	R164I	164	Missense	distal	-3	no	39.842	24.929	PhosphoSitePlus	GDSC;CCLE	24.279	Down-regulation
AGC_RSK_RSKp70_RPS6KB1_ST	P03372	ESR1	P23443	RPS6KB1	S236	R241L	241	Missense	distal	5	no	28.484	29.672	EPSD	GDSC;CCLE	24.279	Up-regulation
AGC_RSK_RSKp70_RPS6KB1_ST	Q05195	MXD1	P23443	RPS6KB1	S194	G196D	196	Missense	proximal	2	no	27.511	25.822	EPSD	GDSC;CCLE	24.279	Down-regulation
AGC_RSK_RSKp70_RPS6KB1_ST	O94763	URI1	P23443	RPS6KB1	T350	G351A	351	Missense	proximal	1	no	37.604	36.121	EPSD	GDSC	24.279	Down-regulation
AGC_RSK_RSKp70_RPS6KB1_ST	O94763	URI1	P23443	RPS6KB1	S359	K362E	362	Missense	distal	3	no	25.048	25.822	EPSD	GDSC;CCLE	24.279	Up-regulation
AGC_RSK_RSKp70_RPS6KB1_ST	O94763	URI1	P23443	RPS6KB1	S372	S372I	372	Missense	central	0	yes	47.363	0.000	PhosphoSitePlus	GDSC;CCLE	24.279	Loss
AGC_RSK_RSKp70_RPS6KB1_ST	O94763	URI1	P23443	RPS6KB1	T373	S372I	372	Missense	proximal	-1	no	24.961	25.016	EPSD	GDSC;CCLE	24.279	Up-regulation
AGC_RSK_RSKp70_RPS6KB1_ST	O94763	URI1	P23443	RPS6KB1	S454	D450N	450	Missense	distal	-4	no	26.663	26.389	EPSD	GDSC;CCLE	24.279	Down-regulation
AGC_RSK_RSKp70_RPS6KB1_ST	O94763	URI1	P23443	RPS6KB1	S454	E459D	459	Missense	distal	5	no	26.663	25.494	EPSD	GDSC	24.279	Down-regulation
AGC_RSK_RSKp70_RPS6KB1_ST	P49959	MRE11	P23443	RPS6KB1	S355	P358Q	358	Missense	distal	3	no	27.539	27.184	EPSD	GDSC	24.279	Down-regulation
AGC_RSK_RSKp70_RPS6KB1_ST	P49959	MRE11	P23443	RPS6KB1	S355	R349Q	349	Missense	distal	-6	no	27.539	27.573	EPSD	GDSC	24.279	Up-regulation
AGC_RSK_RSKp70_RPS6KB1_ST	P49959	MRE11	P23443	RPS6KB1	S447	V444M	444	Missense	distal	-3	no	23.117	32.371	EPSD	GDSC	24.279	Gain
AGC_RSK_RSKp70_RPS6KB1_ST	P49959	MRE11	P23443	RPS6KB1	S590	G589E	589	Missense	proximal	-1	no	25.226	25.147	EPSD	GDSC	24.279	Down-regulation
AGC_RSK_RSKp70_RPS6KB1_ST	P27708	CAD	P23443	RPS6KB1	S1069	R1066M	1066	Missense	distal	-3	no	25.150	19.651	EPSD	GDSC	24.279	Loss
AGC_RSK_RSKp70_RPS6KB1_ST	P27708	CAD	P23443	RPS6KB1	S1118	A1114V	1114	Missense	distal	-4	no	25.410	24.422	EPSD	GDSC	24.279	Down-regulation
AGC_RSK_RSKp70_RPS6KB1_ST	P27708	CAD	P23443	RPS6KB1	S1267	P1264H	1264	Missense	distal	-3	no	24.091	33.224	EPSD	GDSC	24.279	Gain
AGC_RSK_RSKp70_RPS6KB1_ST	P27708	CAD	P23443	RPS6KB1	S1900	V1895I	1895	Missense	distal	-5	no	28.623	26.237	EPSD	GDSC	24.279	Down-regulation
AGC_RSK_RSKp70_RPS6KB1_ST	Q9GZT9	EGLN1	P23443	RPS6KB1	S38	S34G	34	Missense	distal	-4	no	24.319	21.272	EPSD	GDSC;CCLE	24.279	Loss
AGC_RSK_RSKp70_RPS6KB1_ST	O60331	PIP5K1C	P23443	RPS6KB1	S523	A519S	519	Missense	distal	-4	no	26.853	27.976	EPSD	GDSC;CCLE	24.279	Up-regulation
AGC_RSK_RSKp70_RPS6KB1_ST	O60331	PIP5K1C	P23443	RPS6KB1	S541	T543M	543	Missense	proximal	2	no	24.868	24.020	EPSD	GDSC	24.279	Loss
AGC_RSK_RSKp70_RPS6KB1_ST	O60331	PIP5K1C	P23443	RPS6KB1	T553	R550G	550	Missense	distal	-3	no	35.564	27.740	EPSD;PhosphoSitePlus	GDSC	24.279	Down-regulation
AGC_RSK_RSKp70_RPS6KB1_ST	O60331	PIP5K1C	P23443	RPS6KB1	S555	R550G	550	Missense	distal	-5	no	37.679	30.434	PhosphoSitePlus;EPSD	GDSC	24.279	Down-regulation
AGC_RSK_RSKp70_RPS6KB1_ST	P08151	GLI1	P23443	RPS6KB1	S84	P87S	87	Missense	distal	3	no	37.289	39.829	PhosphoSitePlus	GDSC;CCLE	24.279	Up-regulation
AGC_RSK_RSKp70_RPS6KB1_ST	P08151	GLI1	P23443	RPS6KB1	S86	P87S	87	Missense	proximal	1	no	27.111	26.094	EPSD	GDSC;CCLE	24.279	Down-regulation
AGC_RSK_RSKp70_RPS6KB1_ST	P08151	GLI1	P23443	RPS6KB1	S92	P87S	87	Missense	distal	-5	no	21.939	24.877	EPSD	GDSC;CCLE	24.279	Gain
AGC_RSK_RSKp70_RPS6KB1_ST	P08151	GLI1	P23443	RPS6KB1	S544	R542C	542	Missense	proximal	-2	no	26.742	28.336	EPSD	GDSC;CCLE	24.279	Up-regulation
AGC_RSK_RSKp70_RPS6KB1_ST	P08151	GLI1	P23443	RPS6KB1	S544	S545G	545	Missense	proximal	1	no	26.742	27.844	EPSD	GDSC;CCLE	24.279	Up-regulation
AGC_RSK_RSKp70_RPS6KB1_ST	P08151	GLI1	P23443	RPS6KB1	S545	R542C	542	Missense	distal	-3	no	26.328	16.779	EPSD	GDSC;CCLE	24.279	Loss
AGC_RSK_RSKp70_RPS6KB1_ST	P08151	GLI1	P23443	RPS6KB1	S545	S545G	545	Missense	central	0	yes	26.328	0.000	EPSD	GDSC;CCLE	24.279	Loss
AGC_RSK_RSKp70_RPS6KB1_ST	P08151	GLI1	P23443	RPS6KB1	S602	G600C	600	Missense	proximal	-2	no	24.229	26.690	EPSD	GDSC	24.279	Gain
AGC_RSK_RSKp70_RPS6KB1_ST	P08151	GLI1	P23443	RPS6KB1	S934	V936I	936	Missense	proximal	2	no	26.629	27.087	EPSD	GDSC;CCLE	24.279	Up-regulation
AGC_RSK_RSKp70_RPS6KB1_ST	Q6R327	RICTOR	P23443	RPS6KB1	S35	R32L	32	Missense	distal	-3	no	31.100	21.433	EPSD	GDSC;CCLE	24.279	Loss
AGC_RSK_RSKp70_RPS6KB1_ST	Q6R327	RICTOR	P23443	RPS6KB1	S1026	H1033Y	1033	Missense	distal	7	no	29.112	29.060	EPSD	GDSC	24.279	Down-regulation
AGC_RSK_RSKp70_RPS6KB1_ST	Q6R327	RICTOR	P23443	RPS6KB1	S1028	H1033Y	1033	Missense	distal	5	no	25.996	23.628	EPSD	GDSC	24.279	Loss
AGC_RSK_RSKp70_RPS6KB1_ST	Q6R327	RICTOR	P23443	RPS6KB1	S1035	H1033Y	1033	Missense	proximal	-2	no	29.070	29.439	EPSD	GDSC	24.279	Up-regulation
AGC_RSK_RSKp70_RPS6KB1_ST	Q6R327	RICTOR	P23443	RPS6KB1	S1037	H1033Y	1033	Missense	distal	-4	no	31.384	31.874	EPSD	GDSC	24.279	Up-regulation
AGC_RSK_RSKp70_RPS6KB1_ST	Q6R327	RICTOR	P23443	RPS6KB1	S1235	G1242D	1242	Missense	distal	7	no	29.045	28.325	EPSD	GDSC;CCLE	24.279	Down-regulation
AGC_RSK_RSKp70_RPS6KB1_ST	Q6R327	RICTOR	P23443	RPS6KB1	S1237	G1242D	1242	Missense	distal	5	no	26.803	25.380	EPSD	GDSC;CCLE	24.279	Down-regulation
AGC_RSK_RSKp70_RPS6KB1_ST	Q6R327	RICTOR	P23443	RPS6KB1	S1302	A1300T	1300	Missense	proximal	-2	no	29.044	29.018	EPSD	GDSC;CCLE	24.279	Down-regulation
AGC_RSK_RSKp70_RPS6KB1_ST	Q6R327	RICTOR	P23443	RPS6KB1	S1307	A1300T	1300	Missense	distal	-7	no	24.384	24.291	EPSD	GDSC;CCLE	24.279	Down-regulation
AGC_RSK_RSKp70_RPS6KB1_ST	P23588	EIF4B	P23443	RPS6KB1	S35	T32A	32	Missense	distal	-3	no	30.297	30.327	EPSD	GDSC	24.279	Up-regulation
AGC_RSK_RSKp70_RPS6KB1_ST	P23588	EIF4B	P23443	RPS6KB1	S93	D86Y	86	Missense	distal	-7	no	28.236	28.289	EPSD	GDSC;CCLE	24.279	Up-regulation
AGC_RSK_RSKp70_RPS6KB1_ST	P23588	EIF4B	P23443	RPS6KB1	S352	D346A	346	Missense	distal	-6	no	28.095	28.067	EPSD	GDSC;CCLE	24.279	Down-regulation
AGC_RSK_RSKp70_RPS6KB1_ST	P23588	EIF4B	P23443	RPS6KB1	S406	R401G	401	Missense	distal	-5	no	26.685	19.441	EPSD	GDSC;CCLE	24.279	Loss
AGC_RSK_RSKp70_RPS6KB1_ST	P23588	EIF4B	P23443	RPS6KB1	T420	R415Q	415	Missense	distal	-5	no	30.157	18.182	EPSD	GDSC;CCLE	24.279	Loss
AGC_RSK_RSKp70_RPS6KB1_ST	P23588	EIF4B	P23443	RPS6KB1	S422	R415Q	415	Missense	distal	-7	no	44.185	44.255	PhosphoSitePlus	GDSC;CCLE	24.279	Up-regulation
AGC_RSK_RSKp70_RPS6KB1_ST	P23588	EIF4B	P23443	RPS6KB1	S459	P460S	460	Missense	proximal	1	no	26.806	25.788	EPSD	GDSC	24.279	Down-regulation
AGC_RSK_RSKp70_RPS6KB1_ST	P23588	EIF4B	P23443	RPS6KB1	T461	P460S	460	Missense	proximal	-1	no	28.065	27.968	EPSD	GDSC	24.279	Down-regulation
Atypical_Alpha_ChaK_TRPM7_ST	Q96QT4	TRPM7	Q96QT4	TRPM7	T89	S87N	87	Missense	proximal	-2	no	3.909	4.089	EPSD	GDSC;CCLE	3.661	Up-regulation
Atypical_Alpha_ChaK_TRPM7_ST	Q96QT4	TRPM7	Q96QT4	TRPM7	S1255	A1254V	1254	Missense	proximal	-1	no	3.863	3.957	EPSD;PhosphoSitePlus	GDSC	3.661	Up-regulation
Atypical_Alpha_ChaK_TRPM7_ST	Q96QT4	TRPM7	Q96QT4	TRPM7	S1258	A1254V	1254	Missense	distal	-4	no	4.222	4.341	EPSD;PhosphoSitePlus	GDSC	3.661	Up-regulation
Atypical_Alpha_ChaK_TRPM7_ST	Q96QT4	TRPM7	Q96QT4	TRPM7	S1390	S1396Y	1396	Missense	distal	6	no	4.119	3.823	EPSD;PhosphoSitePlus	GDSC;CCLE	3.661	Down-regulation
Atypical_Alpha_ChaK_TRPM7_ST	Q96QT4	TRPM7	Q96QT4	TRPM7	T1405	S1404R	1404	Missense	proximal	-1	no	3.832	4.014	EPSD;PhosphoSitePlus	GDSC	3.661	Up-regulation
Atypical_Alpha_ChaK_TRPM7_ST	Q96QT4	TRPM7	Q96QT4	TRPM7	T1405	K1412E	1412	Missense	distal	7	no	3.832	2.923	EPSD;PhosphoSitePlus	GDSC	3.661	Loss
Atypical_Alpha_ChaK_TRPM7_ST	Q96QT4	TRPM7	Q96QT4	TRPM7	S1407	S1404R	1404	Missense	distal	-3	no	3.651	3.721	EPSD;PhosphoSitePlus	GDSC	3.661	Gain
Atypical_Alpha_ChaK_TRPM7_ST	Q96QT4	TRPM7	Q96QT4	TRPM7	S1407	K1412E	1412	Missense	distal	5	no	3.651	3.735	EPSD;PhosphoSitePlus	GDSC	3.661	Gain
Atypical_Alpha_ChaK_TRPM7_ST	Q96QT4	TRPM7	Q96QT4	TRPM7	S1468	N1466S	1466	Missense	proximal	-2	no	3.848	3.667	EPSD;PhosphoSitePlus	GDSC	3.661	Down-regulation
Atypical_Alpha_ChaK_TRPM7_ST	Q96QT4	TRPM7	Q96QT4	TRPM7	T1471	N1466S	1466	Missense	distal	-5	no	4.008	4.230	EPSD;PhosphoSitePlus	GDSC	3.661	Up-regulation
Atypical_Alpha_ChaK_TRPM7_ST	Q96QT4	TRPM7	Q96QT4	TRPM7	S1598	N1593S	1593	Missense	distal	-5	no	4.441	4.663	EPSD;PhosphoSitePlus	GDSC	3.661	Up-regulation
Atypical_Alpha_ChaK_TRPM7_ST	P35579	MYH9	Q96QT4	TRPM7	S1803	Y1805*	1805	Missense	proximal	2	no	4.692	4.832	EPSD;PhosphoSitePlus	GDSC	3.661	Up-regulation
Atypical_Alpha_ChaK_TRPM7_ST	P35579	MYH9	Q96QT4	TRPM7	S1808	Y1805*	1805	Missense	distal	-3	no	3.994	4.117	PhosphoSitePlus;EPSD	GDSC	3.661	Up-regulation
Atypical_Alpha_ChaK_TRPM7_ST	O00418	EEF2K	Q96QT4	TRPM7	S47	V52A	52	Missense	distal	5	no	4.086	4.364	EPSD	GDSC;CCLE	3.661	Up-regulation
Atypical_Alpha_ChaK_TRPM7_ST	O00418	EEF2K	Q96QT4	TRPM7	S74	Y69H	69	Missense	distal	-5	no	3.677	3.666	EPSD	GDSC;CCLE	3.661	Down-regulation
Atypical_Alpha_ChaK_TRPM7_ST	O00418	EEF2K	Q96QT4	TRPM7	S435	E434*	434	Missense	proximal	-1	no	2.953	3.880	EPSD	GDSC	3.661	Gain
Atypical_Alpha_ChaK_TRPM7_ST	O00418	EEF2K	Q96QT4	TRPM7	S445	G449S	449	Missense	distal	4	no	3.499	3.686	EPSD	GDSC	3.661	Gain
Atypical_Alpha_ChaK_TRPM7_ST	O00418	EEF2K	Q96QT4	TRPM7	S622	G623S	623	Missense	proximal	1	no	3.713	4.054	EPSD	GDSC	3.661	Up-regulation
Atypical_Alpha_ChaK_TRPM7_ST	P28289	TMOD1	Q96QT4	TRPM7	T54	D52N	52	Missense	proximal	-2	no	3.731	3.655	EPSD;PhosphoSitePlus	GDSC;CCLE	3.661	Loss
TK_Axl_MERTK_Y	P42229	STAT5A	Q12866	MERTK	Y171	E178*	178	Missense	distal	7	no	1.910	1.780	EPSD	GDSC	1.889	Loss
TK_Axl_MERTK_Y	P42229	STAT5A	Q12866	MERTK	Y694	P697L	697	Missense	distal	3	no	6.349	6.293	PhosphoSitePlus	GDSC	1.889	Down-regulation
TK_Axl_MERTK_Y	P51692	STAT5B	Q12866	MERTK	Y171	Q167R	167	Missense	distal	-4	no	2.073	2.022	EPSD	GDSC;CCLE	1.889	Down-regulation
TK_Axl_MERTK_Y	P40763	STAT3	Q12866	MERTK	Y705	C712Y	712	Missense	distal	7	no	5.687	5.585	PhosphoSitePlus	GDSC;CCLE	1.889	Down-regulation
STE_STE20_PAKB_PAK6_ST	Q9BY11	PACSIN1	Q9NQU5	PAK6	S339	A334T	334	Missense	distal	-5	no	1.782	1.614	EPSD	GDSC;CCLE	1.514	Down-regulation
STE_STE20_PAKB_PAK6_ST	P53667	LIMK1	Q9NQU5	PAK6	T261	H259R	259	Missense	proximal	-2	no	1.574	1.587	EPSD	GDSC	1.514	Up-regulation
STE_STE20_PAKB_PAK6_ST	P53667	LIMK1	Q9NQU5	PAK6	S427	W434*	434	Missense	distal	7	no	1.865	1.831	EPSD	GDSC	1.514	Down-regulation
STE_STE20_PAKB_PAK6_ST	P53667	LIMK1	Q9NQU5	PAK6	T508	R506C	506	Missense	proximal	-2	no	4.476	4.499	PhosphoSitePlus	GDSC;CCLE	1.514	Up-regulation
STE_STE20_PAKA_PAK1_ST	P36871	PGM1	Q13153	PAK1	S408	A403T	403	Missense	distal	-5	no	22.089	21.890	EPSD	GDSC;CCLE	19.028	Down-regulation
STE_STE20_PAKA_PAK1_ST	P36871	PGM1	Q13153	PAK1	T467	T467N	467	Missense	central	0	yes	22.191	0.000	PhosphoSitePlus	GDSC	19.028	Loss
STE_STE20_PAKA_PAK1_ST	P51114	FXR1	Q13153	PAK1	S438	D431G	431	Missense	distal	-7	no	20.036	19.360	EPSD	GDSC;CCLE	19.028	Down-regulation
STE_STE20_PAKA_PAK1_ST	P51114	FXR1	Q13153	PAK1	S506	S499R	499	Missense	distal	-7	no	24.627	25.196	EPSD	GDSC;CCLE	19.028	Up-regulation
STE_STE20_PAKA_PAK1_ST	P51114	FXR1	Q13153	PAK1	T557	E556*	556	Missense	proximal	-1	no	21.363	18.145	EPSD	GDSC	19.028	Loss
STE_STE20_PAKA_PAK1_ST	Q13153	PAK1	Q13153	PAK1	S165	A163V	163	Missense	proximal	-2	no	20.746	23.006	EPSD	GDSC;CCLE	19.028	Up-regulation
STE_STE20_PAKA_PAK1_ST	Q13153	PAK1	Q13153	PAK1	S259	S259N	259	Missense	central	0	yes	21.435	0.000	EPSD	GDSC;CCLE	19.028	Loss
STE_STE20_PAKA_PAK1_ST	O15143	ARPC1B	Q13153	PAK1	T21	I25T	25	Missense	distal	4	no	21.594	19.709	PhosphoSitePlus	GDSC;CCLE	19.028	Down-regulation
STE_STE20_PAKA_PAK1_ST	P19086	GNAZ	Q13153	PAK1	T182	M181T	181	Missense	proximal	-1	no	22.092	24.413	EPSD	GDSC;CCLE	19.028	Up-regulation
STE_STE20_PAKA_PAK1_ST	P04049	RAF1	Q13153	PAK1	S43	A42V	42	Missense	proximal	-1	no	27.696	28.326	EPSD	GDSC	19.028	Up-regulation
STE_STE20_PAKA_PAK1_ST	P04049	RAF1	Q13153	PAK1	S43	A42T	42	Missense	proximal	-1	no	27.696	30.726	EPSD	GDSC	19.028	Up-regulation
STE_STE20_PAKA_PAK1_ST	P04049	RAF1	Q13153	PAK1	S220	V226I	226	Missense	distal	6	no	19.644	19.522	EPSD	GDSC;CCLE	19.028	Down-regulation
STE_STE20_PAKA_PAK1_ST	P04049	RAF1	Q13153	PAK1	S233	V226I	226	Missense	distal	-7	no	19.309	20.087	EPSD	GDSC;CCLE	19.028	Up-regulation
STE_STE20_PAKA_PAK1_ST	P04049	RAF1	Q13153	PAK1	T258	Q253P	253	Missense	distal	-5	no	18.882	19.675	EPSD	GDSC	19.028	Gain
STE_STE20_PAKA_PAK1_ST	P04049	RAF1	Q13153	PAK1	S259	Q253P	253	Missense	distal	-6	no	24.769	23.962	EPSD	GDSC	19.028	Down-regulation
STE_STE20_PAKA_PAK1_ST	P04049	RAF1	Q13153	PAK1	S338	E343G	343	Missense	distal	5	no	27.636	27.665	EPSD;PhosphoSitePlus	GDSC;CCLE	19.028	Up-regulation
STE_STE20_PAKA_PAK1_ST	P04049	RAF1	Q13153	PAK1	S339	E343G	343	Missense	distal	4	no	26.983	27.940	PhosphoSitePlus;EPSD	GDSC;CCLE	19.028	Up-regulation
STE_STE20_PAKA_PAK1_ST	P04049	RAF1	Q13153	PAK1	S357	S352F	352	Missense	distal	-5	no	18.996	19.426	EPSD	GDSC;CCLE	19.028	Gain
STE_STE20_PAKA_PAK1_ST	Q13418	ILK	Q13153	PAK1	S246	R241W	241	Missense	distal	-5	no	22.329	23.457	PhosphoSitePlus;EPSD	GDSC;CCLE	19.028	Up-regulation
STE_STE20_PAKA_PAK1_ST	Q13418	ILK	Q13153	PAK1	S336	A333V	333	Missense	distal	-3	no	21.384	14.122	EPSD	GDSC;CCLE	19.028	Loss
STE_STE20_PAKA_PAK1_ST	Q13418	ILK	Q13153	PAK1	S336	D330N	330	Missense	distal	-6	no	21.384	21.547	EPSD	GDSC	19.028	Up-regulation
STE_STE20_PAKA_PAK1_ST	Q92934	BAD	Q13153	PAK1	S134	T137K	137	Missense	distal	3	no	25.807	25.673	EPSD;PhosphoSitePlus	GDSC	19.028	Down-regulation
STE_STE20_PAKA_PAK1_ST	Q92934	BAD	Q13153	PAK1	S134	L129F	129	Missense	distal	-5	no	25.807	25.477	EPSD;PhosphoSitePlus	GDSC	19.028	Down-regulation
STE_STE20_PAKA_PAK1_ST	Q92934	BAD	Q13153	PAK1	S144	F151L	151	Missense	distal	7	no	20.524	20.456	EPSD	GDSC;CCLE	19.028	Down-regulation
STE_STE20_PAKA_PAK1_ST	Q92934	BAD	Q13153	PAK1	S144	T137K	137	Missense	distal	-7	no	20.524	20.506	EPSD	GDSC	19.028	Down-regulation
STE_STE20_PAKA_PAK1_ST	Q13233	MAP3K1	Q13153	PAK1	S292	R288*	288	Missense	distal	-4	no	19.861	18.167	EPSD	GDSC	19.028	Loss
STE_STE20_PAKA_PAK1_ST	Q99426	TBCB	Q13153	PAK1	S29	R27P	27	Missense	proximal	-2	no	25.813	22.288	EPSD	GDSC;CCLE	19.028	Down-regulation
STE_STE20_PAKA_PAK1_ST	Q99426	TBCB	Q13153	PAK1	T33	R27P	27	Missense	distal	-6	no	26.407	24.339	EPSD	GDSC;CCLE	19.028	Down-regulation
STE_STE20_PAKA_PAK1_ST	Q99661	KIF2C	Q13153	PAK1	T116	T123M	123	Missense	distal	7	no	25.853	26.283	EPSD	GDSC	19.028	Up-regulation
STE_STE20_PAKA_PAK1_ST	Q99661	KIF2C	Q13153	PAK1	S144	F143L	143	Missense	proximal	-1	no	22.791	22.942	EPSD	GDSC;CCLE	19.028	Up-regulation
STE_STE20_PAKA_PAK1_ST	Q99661	KIF2C	Q13153	PAK1	S166	Q172*	172	Missense	distal	6	no	22.559	23.465	EPSD	GDSC	19.028	Up-regulation
STE_STE20_PAKA_PAK1_ST	Q99661	KIF2C	Q13153	PAK1	S192	S192L	192	Missense	central	0	yes	28.284	0.000	PhosphoSitePlus;EPSD	GDSC;CCLE	19.028	Loss
STE_STE20_PAKA_PAK1_ST	Q99661	KIF2C	Q13153	PAK1	S192	V198G	198	Missense	distal	6	no	28.284	28.310	PhosphoSitePlus;EPSD	GDSC	19.028	Up-regulation
STE_STE20_PAKA_PAK1_ST	P18669	PGAM1	Q13153	PAK1	S23	Y26D	26	Missense	distal	3	no	23.434	21.099	PhosphoSitePlus;EPSD	GDSC	19.028	Down-regulation
STE_STE20_PAKA_PAK1_ST	P18669	PGAM1	Q13153	PAK1	T103	E102K	102	Missense	proximal	-1	no	17.710	20.191	EPSD	GDSC;CCLE	19.028	Gain
STE_STE20_PAKA_PAK1_ST	P18669	PGAM1	Q13153	PAK1	T146	C153R	153	Missense	distal	7	no	19.034	18.796	EPSD	GDSC;CCLE	19.028	Loss
STE_STE20_PAKA_PAK1_ST	P78545	ELF3	Q13153	PAK1	S207	T201I	201	Missense	distal	-6	no	22.411	20.363	PhosphoSitePlus	GDSC;CCLE	19.028	Down-regulation
STE_STE20_PAKA_PAK1_ST	P78545	ELF3	Q13153	PAK1	S254	R247*	247	Missense	distal	-7	no	24.714	21.657	EPSD	GDSC	19.028	Down-regulation
STE_STE20_PAKA_PAK1_ST	P35222	CTNNB1	Q13153	PAK1	S552	R549H	549	Missense	distal	-3	no	29.381	23.310	EPSD	GDSC;CCLE	19.028	Down-regulation
STE_STE20_PAKA_PAK1_ST	P35222	CTNNB1	Q13153	PAK1	S675	Y670*	670	Missense	distal	-5	no	27.663	28.019	PhosphoSitePlus	GDSC	19.028	Up-regulation
STE_STE20_PAKA_PAK1_ST	Q14247	CTTN	Q13153	PAK1	S106	E103K	103	Missense	distal	-3	no	7.323	21.115	EPSD	GDSC;CCLE	19.028	Gain
STE_STE20_PAKA_PAK1_ST	Q14247	CTTN	Q13153	PAK1	S405	Q409K	409	Missense	distal	4	no	19.139	19.852	EPSD;PhosphoSitePlus	GDSC;CCLE	19.028	Up-regulation
STE_STE20_PAKA_PAK1_ST	P49023	PXN	Q13153	PAK1	S303	R301G	301	Missense	proximal	-2	no	23.384	13.821	EPSD	GDSC	19.028	Loss
STE_STE20_PAKA_PAK1_ST	P49023	PXN	Q13153	PAK1	S303	S302G	302	Missense	proximal	-1	no	23.384	20.396	EPSD	GDSC	19.028	Down-regulation
STE_STE20_PAKA_PAK1_ST	P49023	PXN	Q13153	PAK1	S303	G305R	305	Missense	proximal	2	no	23.384	21.850	EPSD	GDSC	19.028	Down-regulation
STE_STE20_PAKA_PAK1_ST	P49023	PXN	Q13153	PAK1	S320	S321N	321	Missense	proximal	1	no	18.941	19.033	EPSD	GDSC;CCLE	19.028	Gain
STE_STE20_PAKA_PAK1_ST	P49023	PXN	Q13153	PAK1	S332	G331R	331	Missense	proximal	-1	no	18.046	22.115	EPSD	GDSC	19.028	Gain
STE_STE20_PAKA_PAK1_ST	Q9Y2X7	GIT1	Q13153	PAK1	S154	G156S	156	Missense	proximal	2	no	24.221	23.073	EPSD	GDSC;CCLE	19.028	Down-regulation
STE_STE20_PAKA_PAK1_ST	P53350	PLK1	Q13153	PAK1	S565	E568*	568	Missense	distal	3	no	24.734	26.550	EPSD	GDSC	19.028	Up-regulation
STE_STE20_PAKA_PAK1_ST	P21333	FLNA	Q13153	PAK1	S204	A206V	206	Missense	proximal	2	no	19.434	19.504	EPSD	GDSC;CCLE	19.028	Up-regulation
STE_STE20_PAKA_PAK1_ST	P21333	FLNA	Q13153	PAK1	T341	P348L	348	Missense	distal	7	no	19.929	19.910	EPSD	GDSC;CCLE	19.028	Down-regulation
STE_STE20_PAKA_PAK1_ST	P21333	FLNA	Q13153	PAK1	T341	R340H	340	Missense	proximal	-1	no	19.929	17.121	EPSD	GDSC	19.028	Loss
STE_STE20_PAKA_PAK1_ST	P21333	FLNA	Q13153	PAK1	S343	P348L	348	Missense	distal	5	no	28.456	28.442	EPSD	GDSC;CCLE	19.028	Down-regulation
STE_STE20_PAKA_PAK1_ST	P21333	FLNA	Q13153	PAK1	S343	R340H	340	Missense	distal	-3	no	28.456	22.385	EPSD	GDSC	19.028	Down-regulation
STE_STE20_PAKA_PAK1_ST	P21333	FLNA	Q13153	PAK1	S440	Q447*	447	Missense	distal	7	no	20.064	20.393	EPSD	GDSC	19.028	Up-regulation
STE_STE20_PAKA_PAK1_ST	P21333	FLNA	Q13153	PAK1	T1286	S1279N	1279	Missense	distal	-7	no	19.276	18.610	EPSD	GDSC;CCLE	19.028	Loss
STE_STE20_PAKA_PAK1_ST	P21333	FLNA	Q13153	PAK1	T1286	R1283Q	1283	Missense	distal	-3	no	19.276	10.552	EPSD	GDSC;CCLE	19.028	Loss
STE_STE20_PAKA_PAK1_ST	P21333	FLNA	Q13153	PAK1	S1522	S1520N	1520	Missense	proximal	-2	no	18.716	21.274	EPSD	GDSC;CCLE	19.028	Gain
STE_STE20_PAKA_PAK1_ST	P21333	FLNA	Q13153	PAK1	S1812	A1816V	1816	Missense	distal	4	no	22.366	23.010	EPSD	GDSC;CCLE	19.028	Up-regulation
STE_STE20_PAKA_PAK1_ST	P21333	FLNA	Q13153	PAK1	S1812	R1809Q	1809	Missense	distal	-3	no	22.366	13.642	EPSD	GDSC;CCLE	19.028	Loss
STE_STE20_PAKA_PAK1_ST	P21333	FLNA	Q13153	PAK1	T2336	R2334C	2334	Missense	proximal	-2	no	27.160	14.439	EPSD	GDSC	19.028	Loss
STE_STE20_PAKA_PAK1_ST	P52565	ARHGDIA	Q13153	PAK1	S174	R172Q	172	Missense	proximal	-2	no	22.183	12.976	PhosphoSitePlus;EPSD	GDSC;CCLE	19.028	Loss
STE_STE20_PAKA_PAK1_ST	Q15365	PCBP1	Q13153	PAK1	T127	T127R	127	Missense	central	0	yes	19.625	0.000	EPSD;PhosphoSitePlus	GDSC;CCLE	19.028	Loss
STE_STE20_PAKA_PAK1_ST	P15056	BRAF	Q13153	PAK1	S323	A320S	320	Missense	distal	-3	no	20.800	18.752	EPSD	GDSC;CCLE	19.028	Loss
STE_STE20_PAKA_PAK1_ST	P15056	BRAF	Q13153	PAK1	S363	D361G	361	Missense	proximal	-2	no	19.461	16.233	EPSD	GDSC;CCLE	19.028	Loss
STE_STE20_PAKA_PAK1_ST	P15056	BRAF	Q13153	PAK1	S364	D361G	361	Missense	distal	-3	no	22.223	21.303	EPSD	GDSC;CCLE	19.028	Down-regulation
STE_STE20_PAKA_PAK1_ST	P15056	BRAF	Q13153	PAK1	S365	D361G	361	Missense	distal	-4	no	20.673	20.193	EPSD	GDSC;CCLE	19.028	Down-regulation
STE_STE20_PAKA_PAK1_ST	Q96T58	SPEN	Q13153	PAK1	S43	V47M	47	Missense	distal	4	no	28.417	28.520	EPSD	GDSC;CCLE	19.028	Up-regulation
STE_STE20_PAKA_PAK1_ST	Q96T58	SPEN	Q13153	PAK1	S278	D282E	282	Missense	distal	4	no	20.454	19.954	EPSD	GDSC;CCLE	19.028	Down-regulation
STE_STE20_PAKA_PAK1_ST	Q96T58	SPEN	Q13153	PAK1	S278	S283*	283	Missense	distal	5	no	20.454	20.489	EPSD	GDSC	19.028	Up-regulation
STE_STE20_PAKA_PAK1_ST	Q96T58	SPEN	Q13153	PAK1	S279	S283*	283	Missense	distal	4	no	17.662	20.241	EPSD	GDSC	19.028	Gain
STE_STE20_PAKA_PAK1_ST	Q96T58	SPEN	Q13153	PAK1	S334	R332C	332	Missense	proximal	-2	no	27.419	14.698	EPSD	GDSC;CCLE	19.028	Loss
STE_STE20_PAKA_PAK1_ST	Q96T58	SPEN	Q13153	PAK1	T534	Q531R	531	Missense	distal	-3	no	13.192	21.916	EPSD	GDSC;CCLE	19.028	Gain
STE_STE20_PAKA_PAK1_ST	Q96T58	SPEN	Q13153	PAK1	S727	R733C	733	Missense	distal	6	no	19.497	20.133	EPSD	GDSC	19.028	Up-regulation
STE_STE20_PAKA_PAK1_ST	Q96T58	SPEN	Q13153	PAK1	S736	R733C	733	Missense	distal	-3	no	25.750	5.795	EPSD	GDSC	19.028	Loss
STE_STE20_PAKA_PAK1_ST	Q96T58	SPEN	Q13153	PAK1	S946	E950D	950	Missense	distal	4	no	20.456	20.956	EPSD	GDSC;CCLE	19.028	Up-regulation
STE_STE20_PAKA_PAK1_ST	Q96T58	SPEN	Q13153	PAK1	S1006	P1007T	1007	Missense	proximal	1	no	20.962	21.488	EPSD	GDSC	19.028	Up-regulation
STE_STE20_PAKA_PAK1_ST	Q96T58	SPEN	Q13153	PAK1	S1082	R1079S	1079	Missense	distal	-3	no	20.210	11.538	EPSD	GDSC;CCLE	19.028	Loss
STE_STE20_PAKA_PAK1_ST	Q96T58	SPEN	Q13153	PAK1	S1364	R1371*	1371	Missense	distal	7	no	23.112	23.437	EPSD	GDSC	19.028	Up-regulation
STE_STE20_PAKA_PAK1_ST	Q96T58	SPEN	Q13153	PAK1	S1364	S1364G	1364	Missense	central	0	yes	23.112	0.000	EPSD	GDSC	19.028	Loss
STE_STE20_PAKA_PAK1_ST	Q96T58	SPEN	Q13153	PAK1	S1369	R1371*	1371	Missense	proximal	2	no	22.353	24.183	EPSD	GDSC	19.028	Up-regulation
STE_STE20_PAKA_PAK1_ST	Q96T58	SPEN	Q13153	PAK1	S1369	S1364G	1364	Missense	distal	-5	no	22.353	23.267	EPSD	GDSC	19.028	Up-regulation
STE_STE20_PAKA_PAK1_ST	Q96T58	SPEN	Q13153	PAK1	S1396	K1389N	1389	Missense	distal	-7	no	23.744	23.128	EPSD	GDSC;CCLE	19.028	Down-regulation
STE_STE20_PAKA_PAK1_ST	Q96T58	SPEN	Q13153	PAK1	S1424	S1424G	1424	Missense	central	0	yes	19.984	0.000	EPSD	GDSC	19.028	Loss
STE_STE20_PAKA_PAK1_ST	Q96T58	SPEN	Q13153	PAK1	S1424	D1419G	1419	Missense	distal	-5	no	19.984	20.416	EPSD	GDSC;CCLE	19.028	Up-regulation
STE_STE20_PAKA_PAK1_ST	Q96T58	SPEN	Q13153	PAK1	S1433	D1437G	1437	Missense	distal	4	no	21.348	21.806	EPSD	GDSC;CCLE	19.028	Up-regulation
STE_STE20_PAKA_PAK1_ST	Q96T58	SPEN	Q13153	PAK1	T1441	D1437G	1437	Missense	distal	-4	no	19.825	19.345	EPSD	GDSC;CCLE	19.028	Down-regulation
STE_STE20_PAKA_PAK1_ST	Q96T58	SPEN	Q13153	PAK1	S1453	E1449Q	1449	Missense	distal	-4	no	19.527	19.344	EPSD	GDSC;CCLE	19.028	Down-regulation
STE_STE20_PAKA_PAK1_ST	Q96T58	SPEN	Q13153	PAK1	S1455	E1449Q	1449	Missense	distal	-6	no	19.989	19.629	EPSD	GDSC;CCLE	19.028	Down-regulation
STE_STE20_PAKA_PAK1_ST	Q96T58	SPEN	Q13153	PAK1	S1797	P1795S	1795	Missense	proximal	-2	no	19.532	14.904	EPSD	GDSC	19.028	Loss
STE_STE20_PAKA_PAK1_ST	Q96T58	SPEN	Q13153	PAK1	S1797	P1799S	1799	Missense	proximal	2	no	19.532	18.886	EPSD	GDSC;CCLE	19.028	Loss
STE_STE20_PAKA_PAK1_ST	Q96T58	SPEN	Q13153	PAK1	S1802	P1795S	1795	Missense	distal	-7	no	19.738	19.995	EPSD	GDSC	19.028	Up-regulation
STE_STE20_PAKA_PAK1_ST	Q96T58	SPEN	Q13153	PAK1	S1802	P1799S	1799	Missense	distal	-3	no	19.738	16.749	EPSD	GDSC;CCLE	19.028	Loss
STE_STE20_PAKA_PAK1_ST	Q96T58	SPEN	Q13153	PAK1	S1897	R1898*	1898	Missense	proximal	1	no	19.043	18.278	EPSD	GDSC	19.028	Loss
STE_STE20_PAKA_PAK1_ST	Q96T58	SPEN	Q13153	PAK1	S1897	N1903S	1903	Missense	distal	6	no	19.043	18.859	EPSD	GDSC;CCLE	19.028	Loss
STE_STE20_PAKA_PAK1_ST	Q96T58	SPEN	Q13153	PAK1	S1986	A1991V	1991	Missense	distal	5	no	19.175	19.176	EPSD	GDSC;CCLE	19.028	Up-regulation
STE_STE20_PAKA_PAK1_ST	Q96T58	SPEN	Q13153	PAK1	S1986	A1990T	1990	Missense	distal	4	no	19.175	17.832	EPSD	GDSC;CCLE	19.028	Loss
STE_STE20_PAKA_PAK1_ST	Q96T58	SPEN	Q13153	PAK1	S2407	Q2413*	2413	Missense	distal	6	no	19.744	20.650	EPSD	GDSC	19.028	Up-regulation
STE_STE20_PAKA_PAK1_ST	Q96T58	SPEN	Q13153	PAK1	S2512	S2515F	2515	Missense	distal	3	no	21.026	21.607	EPSD	GDSC;CCLE	19.028	Up-regulation
STE_STE20_PAKA_PAK1_ST	Q96T58	SPEN	Q13153	PAK1	T2685	V2683M	2683	Missense	proximal	-2	no	19.856	21.176	EPSD	GDSC;CCLE	19.028	Up-regulation
STE_STE20_PAKA_PAK1_ST	P16949	STMN1	Q13153	PAK1	S16	E10K	10	Missense	distal	-6	no	26.353	25.197	EPSD;PhosphoSitePlus	GDSC;CCLE	19.028	Down-regulation
STE_STE20_PAKA_PAK1_ST	P16949	STMN1	Q13153	PAK1	S16	E10*	10	Missense	distal	-6	no	26.353	20.774	EPSD;PhosphoSitePlus	GDSC	19.028	Down-regulation
STE_STE20_PAKA_PAK1_ST	P16949	STMN1	Q13153	PAK1	S38	P36T	36	Missense	proximal	-2	no	19.215	17.877	PhosphoSitePlus;EPSD	GDSC;CCLE	19.028	Loss
STE_STE20_PAKA_PAK1_ST	P35240	NF2	Q13153	PAK1	S255	R262*	262	Missense	distal	7	no	21.639	21.964	EPSD	GDSC	19.028	Up-regulation
STE_STE20_PAKA_PAK1_ST	P35240	NF2	Q13153	PAK1	S255	N248S	248	Missense	distal	-7	no	21.639	22.305	EPSD	GDSC;CCLE	19.028	Up-regulation
STE_STE20_PAKA_PAK1_ST	P35240	NF2	Q13153	PAK1	S265	R262*	262	Missense	distal	-3	no	19.418	-16.972	EPSD	GDSC	19.028	Loss
STE_STE20_PAKA_PAK1_ST	P35240	NF2	Q13153	PAK1	S265	I264V	264	Missense	proximal	-1	no	19.418	17.874	EPSD	GDSC;CCLE	19.028	Loss
STE_STE20_PAKA_PAK1_ST	P35240	NF2	Q13153	PAK1	S315	Q320*	320	Missense	distal	5	no	19.055	19.093	EPSD	GDSC	19.028	Up-regulation
STE_STE20_PAKA_PAK1_ST	Q9UQ80	PA2G4	Q13153	PAK1	S79	S81L	81	Missense	proximal	2	no	18.527	19.341	EPSD	GDSC;CCLE	19.028	Gain
STE_STE20_PAKA_PAK1_ST	Q9UQ80	PA2G4	Q13153	PAK1	T261	S262L	262	Missense	proximal	1	no	23.041	23.212	PhosphoSitePlus	GDSC;CCLE	19.028	Up-regulation
STE_STE20_PAKA_PAK1_ST	P53667	LIMK1	Q13153	PAK1	T261	H259R	259	Missense	proximal	-2	no	15.777	21.191	EPSD	GDSC	19.028	Gain
STE_STE20_PAKA_PAK1_ST	P53667	LIMK1	Q13153	PAK1	S337	P336L	336	Missense	proximal	-1	no	17.797	21.989	EPSD	GDSC	19.028	Gain
STE_STE20_PAKA_PAK1_ST	P53667	LIMK1	Q13153	PAK1	S430	W434*	434	Missense	distal	4	no	22.952	24.018	EPSD	GDSC	19.028	Up-regulation
STE_STE20_PAKA_PAK1_ST	P53667	LIMK1	Q13153	PAK1	T508	R506C	506	Missense	proximal	-2	no	23.947	11.227	PhosphoSitePlus	GDSC;CCLE	19.028	Loss
STE_STE20_PAKA_PAK1_ST	Q70Z35	PREX2	Q13153	PAK1	S901	Q898H	898	Missense	distal	-3	no	19.357	22.010	EPSD	GDSC;CCLE	19.028	Up-regulation
STE_STE20_PAKA_PAK1_ST	Q70Z35	PREX2	Q13153	PAK1	S901	S902R	902	Missense	proximal	1	no	19.357	19.760	EPSD	GDSC	19.028	Up-regulation
STE_STE20_PAKA_PAK1_ST	Q70Z35	PREX2	Q13153	PAK1	S907	S902R	902	Missense	distal	-5	no	23.618	23.588	EPSD	GDSC	19.028	Down-regulation
STE_STE20_PAKA_PAK1_ST	Q70Z35	PREX2	Q13153	PAK1	S1065	R1062H	1062	Missense	distal	-3	no	31.089	25.017	EPSD	GDSC;CCLE	19.028	Down-regulation
STE_STE20_PAKA_PAK1_ST	Q70Z35	PREX2	Q13153	PAK1	S1065	R1062L	1062	Missense	distal	-3	no	31.089	24.598	EPSD	GDSC;CCLE	19.028	Down-regulation
STE_STE20_PAKA_PAK1_ST	Q8IYU2	HACE1	Q13153	PAK1	S385	N381K	381	Missense	distal	-4	no	27.095	27.805	PhosphoSitePlus	GDSC;CCLE	19.028	Up-regulation
STE_STE20_PAKA_PAK1_ST	Q8IYU2	HACE1	Q13153	PAK1	T386	N381K	381	Missense	distal	-5	no	19.413	18.894	EPSD	GDSC;CCLE	19.028	Loss
STE_STE20_PAKA_PAK1_ST	P03372	ESR1	Q13153	PAK1	S154	R151H	151	Missense	distal	-3	no	26.206	20.134	EPSD	GDSC	19.028	Down-regulation
STE_STE20_PAKA_PAK1_ST	P03372	ESR1	Q13153	PAK1	S154	G160S	160	Missense	distal	6	no	26.206	25.843	EPSD	GDSC	19.028	Down-regulation
STE_STE20_PAKA_PAK1_ST	P03372	ESR1	Q13153	PAK1	S167	G160S	160	Missense	distal	-7	no	18.361	19.298	EPSD	GDSC	19.028	Gain
STE_STE20_PAKA_PAK1_ST	P03372	ESR1	Q13153	PAK1	S236	R241L	241	Missense	distal	5	no	25.537	25.551	EPSD	GDSC;CCLE	19.028	Up-regulation
STE_STE20_PAKA_PAK1_ST	P03372	ESR1	Q13153	PAK1	S305	K299N	299	Missense	distal	-6	no	23.459	23.880	PhosphoSitePlus	GDSC;CCLE	19.028	Up-regulation
STE_STE20_PAKA_PAK1_ST	P03372	ESR1	Q13153	PAK1	S305	I298V	298	Missense	distal	-7	no	23.459	22.681	PhosphoSitePlus	GDSC	19.028	Down-regulation
STE_STE20_PAKA_PAK1_ST	Q15746	MYLK	Q13153	PAK1	S16	S13Y	13	Missense	distal	-3	no	16.218	19.122	EPSD	GDSC;CCLE	19.028	Gain
STE_STE20_PAKA_PAK1_ST	Q15746	MYLK	Q13153	PAK1	S259	E263*	263	Missense	distal	4	no	18.258	20.586	EPSD	GDSC	19.028	Gain
STE_STE20_PAKA_PAK1_ST	Q15746	MYLK	Q13153	PAK1	S343	P336L	336	Missense	distal	-7	no	20.279	19.833	EPSD	GDSC	19.028	Down-regulation
STE_STE20_PAKA_PAK1_ST	Q15746	MYLK	Q13153	PAK1	S848	G847V	847	Missense	proximal	-1	no	23.409	24.476	EPSD	GDSC;CCLE	19.028	Up-regulation
STE_STE20_PAKA_PAK1_ST	Q15746	MYLK	Q13153	PAK1	S947	R954H	954	Missense	distal	7	no	19.631	19.678	EPSD	GDSC;CCLE	19.028	Up-regulation
STE_STE20_PAKA_PAK1_ST	Q15746	MYLK	Q13153	PAK1	S1063	E1066D	1066	Missense	distal	3	no	19.809	21.020	EPSD	GDSC	19.028	Up-regulation
STE_STE20_PAKA_PAK1_ST	Q15746	MYLK	Q13153	PAK1	S1208	V1213L	1213	Missense	distal	5	no	28.909	28.908	EPSD	GDSC;CCLE	19.028	Down-regulation
STE_STE20_PAKA_PAK1_ST	Q15746	MYLK	Q13153	PAK1	S1209	V1213L	1213	Missense	distal	4	no	20.433	19.607	EPSD	GDSC;CCLE	19.028	Down-regulation
STE_STE20_PAKA_PAK1_ST	Q15746	MYLK	Q13153	PAK1	S1760	L1767P	1767	Missense	distal	7	no	25.701	25.720	EPSD	GDSC;CCLE	19.028	Up-regulation
STE_STE20_PAKA_PAK1_ST	Q15746	MYLK	Q13153	PAK1	S1772	G1775E	1775	Missense	distal	3	no	20.841	18.329	PhosphoSitePlus	GDSC;CCLE	19.028	Loss
STE_STE20_PAKA_PAK1_ST	Q15746	MYLK	Q13153	PAK1	S1772	L1767P	1767	Missense	distal	-5	no	20.841	20.942	PhosphoSitePlus	GDSC;CCLE	19.028	Up-regulation
STE_STE20_PAKA_PAK1_ST	Q15746	MYLK	Q13153	PAK1	S1772	S1776P	1776	Missense	distal	4	no	20.841	23.191	PhosphoSitePlus	GDSC;CCLE	19.028	Up-regulation
STE_STE20_PAKA_PAK1_ST	Q15746	MYLK	Q13153	PAK1	S1773	G1775E	1775	Missense	proximal	2	no	22.812	21.692	EPSD	GDSC;CCLE	19.028	Down-regulation
STE_STE20_PAKA_PAK1_ST	Q15746	MYLK	Q13153	PAK1	S1773	L1767P	1767	Missense	distal	-6	no	22.812	22.966	EPSD	GDSC;CCLE	19.028	Up-regulation
STE_STE20_PAKA_PAK1_ST	Q15746	MYLK	Q13153	PAK1	S1773	S1776P	1776	Missense	distal	3	no	22.812	25.193	EPSD	GDSC;CCLE	19.028	Up-regulation
STE_STE20_PAKA_PAK1_ST	Q15746	MYLK	Q13153	PAK1	T1774	G1775E	1775	Missense	proximal	1	no	21.034	21.288	EPSD	GDSC;CCLE	19.028	Up-regulation
STE_STE20_PAKA_PAK1_ST	Q15746	MYLK	Q13153	PAK1	T1774	L1767P	1767	Missense	distal	-7	no	21.034	21.479	EPSD	GDSC;CCLE	19.028	Up-regulation
STE_STE20_PAKA_PAK1_ST	Q15746	MYLK	Q13153	PAK1	T1774	S1776P	1776	Missense	proximal	2	no	21.034	21.679	EPSD	GDSC;CCLE	19.028	Up-regulation
STE_STE20_PAKA_PAK1_ST	Q15746	MYLK	Q13153	PAK1	S1779	G1775E	1775	Missense	distal	-4	no	18.598	19.199	EPSD	GDSC;CCLE	19.028	Gain
STE_STE20_PAKA_PAK1_ST	Q15746	MYLK	Q13153	PAK1	S1779	S1776P	1776	Missense	distal	-3	no	18.598	21.587	EPSD	GDSC;CCLE	19.028	Gain
STE_STE20_PAKA_PAK1_ST	Q15746	MYLK	Q13153	PAK1	S1788	E1790A	1790	Missense	proximal	2	no	19.496	20.373	EPSD	GDSC	19.028	Up-regulation
STE_STE20_PAKA_PAK1_ST	Q15746	MYLK	Q13153	PAK1	S1788	L1786I	1786	Missense	proximal	-2	no	19.496	21.776	EPSD	GDSC	19.028	Up-regulation
STE_STE20_PAKA_PAK1_ST	P08670	VIM	Q13153	PAK1	T426	S430L	430	Missense	distal	4	no	18.484	19.277	EPSD	GDSC;CCLE	19.028	Gain
Atypical_Alpha_ChaK_TRPM6_ST	Q9BX84	TRPM6	Q9BX84	TRPM6	T693	R689L	689	Missense	distal	-4	no	1.117	1.050	EPSD	GDSC	1.085	Loss
Atypical_Alpha_ChaK_TRPM6_ST	Q9BX84	TRPM6	Q9BX84	TRPM6	T696	R689L	689	Missense	distal	-7	no	1.751	1.902	EPSD	GDSC	1.085	Up-regulation
Atypical_Alpha_ChaK_TRPM6_ST	Q9BX84	TRPM6	Q9BX84	TRPM6	S1560	S1560*	1560	Missense	central	0	yes	1.569	0.000	EPSD	GDSC	1.085	Loss
Atypical_Alpha_ChaK_TRPM6_ST	Q9BX84	TRPM6	Q9BX84	TRPM6	T1851	K1848E	1848	Missense	distal	-3	no	5.933	5.936	PhosphoSitePlus	GDSC;CCLE	1.085	Up-regulation
Other_WNK_WNK1_ST	O94913	PCF11	Q9H4A3	WNK1	T830	G829R	829	Missense	proximal	-1	no	-0.001	0.000	EPSD	GDSC;CCLE	0.000	Gain
Other_WNK_WNK1_ST	O95747	OXSR1	Q9H4A3	WNK1	S339	G334R	334	Missense	distal	-5	no	0.000	0.001	EPSD	GDSC;CCLE	0.000	Up-regulation
Other_WNK_WNK1_ST	Q9H4A3	WNK1	Q9H4A3	WNK1	S167	L171F	171	Missense	distal	4	no	0.000	-0.001	EPSD	GDSC;CCLE	0.000	Loss
Other_WNK_WNK1_ST	Q9H4A3	WNK1	Q9H4A3	WNK1	S1300	S1300F	1300	Missense	central	0	yes	0.000	0.000	EPSD	GDSC;CCLE	0.000	Loss
Other_WNK_WNK1_ST	Q9H4A3	WNK1	Q9H4A3	WNK1	S1528	S1535R	1535	Missense	distal	7	no	-0.001	0.000	EPSD	GDSC	0.000	Gain
Other_WNK_WNK1_ST	Q9H4A3	WNK1	Q9H4A3	WNK1	S2190	P2184L	2184	Missense	distal	-6	no	-0.001	0.000	EPSD	GDSC;CCLE	0.000	Gain
Other_WNK_WNK1_ST	Q9UEW8	STK39	Q9H4A3	WNK1	S114	N120K	120	Missense	distal	6	no	0.001	0.000	EPSD	GDSC	0.000	Down-regulation
TK_InsR_INSR_Y	P35568	IRS1	P06213	INSR	Y551	A546V	546	Missense	distal	-5	no	10.566	11.003	EPSD	GDSC;CCLE	10.312	Up-regulation
TK_InsR_INSR_Y	P35568	IRS1	P06213	INSR	Y750	D755A	755	Missense	distal	5	no	10.498	10.897	EPSD	GDSC	10.312	Up-regulation
TK_InsR_INSR_Y	P35568	IRS1	P06213	INSR	Y896	G902V	902	Missense	distal	6	no	13.644	13.553	EPSD;PhosphoSitePlus	GDSC;CCLE	10.312	Down-regulation
TK_InsR_INSR_Y	P35568	IRS1	P06213	INSR	Y896	G902R	902	Missense	distal	6	no	13.644	13.709	EPSD;PhosphoSitePlus	GDSC;CCLE	10.312	Up-regulation
TK_InsR_INSR_Y	P35568	IRS1	P06213	INSR	Y1179	L1177F	1177	Missense	proximal	-2	no	15.829	15.445	EPSD;PhosphoSitePlus	GDSC;CCLE	10.312	Down-regulation
TK_InsR_INSR_Y	P35568	IRS1	P06213	INSR	Y1229	S1233N	1233	Missense	distal	4	no	10.599	10.264	EPSD	GDSC;CCLE	10.312	Loss
TK_InsR_INSR_Y	P06213	INSR	P06213	INSR	Y1011	D1014E	1014	Missense	distal	3	no	10.498	10.350	EPSD;PhosphoSitePlus	GDSC;CCLE	10.312	Down-regulation
TK_InsR_INSR_Y	P06213	INSR	P06213	INSR	Y1011	P1007S	1007	Missense	distal	-4	no	10.498	12.632	EPSD;PhosphoSitePlus	GDSC;CCLE	10.312	Up-regulation
TK_InsR_INSR_Y	P06213	INSR	P06213	INSR	Y1355	E1357K	1357	Missense	proximal	2	no	11.720	11.106	EPSD;PhosphoSitePlus	GDSC;CCLE	10.312	Down-regulation
TK_InsR_INSR_Y	P06213	INSR	P06213	INSR	Y1355	Y1361C	1361	Missense	distal	6	no	11.720	11.656	EPSD;PhosphoSitePlus	GDSC;CCLE	10.312	Down-regulation
TK_InsR_INSR_Y	Q13480	GAB1	P06213	INSR	Y373	A366T	366	Missense	distal	-7	no	11.973	12.605	EPSD;PhosphoSitePlus	GDSC;CCLE	10.312	Up-regulation
TK_InsR_INSR_Y	Q13480	GAB1	P06213	INSR	Y373	D370G	370	Missense	distal	-3	no	11.973	10.045	EPSD;PhosphoSitePlus	GDSC;CCLE	10.312	Loss
TK_InsR_INSR_Y	Q13480	GAB1	P06213	INSR	Y373	C374R	374	Missense	proximal	1	no	11.973	11.978	EPSD;PhosphoSitePlus	GDSC;CCLE	10.312	Up-regulation
TK_InsR_INSR_Y	Q13480	GAB1	P06213	INSR	Y406	A411E	411	Missense	distal	5	no	10.487	10.060	EPSD	GDSC	10.312	Loss
TK_InsR_INSR_Y	Q13480	GAB1	P06213	INSR	Y447	L443P	443	Missense	distal	-4	no	17.503	18.318	EPSD;PhosphoSitePlus	GDSC;CCLE	10.312	Up-regulation
TK_InsR_INSR_Y	Q13017	ARHGAP5	P06213	INSR	Y306	G311V	311	Missense	distal	5	no	13.779	13.936	PhosphoSitePlus	GDSC;CCLE	10.312	Up-regulation
TK_InsR_INSR_Y	Q13017	ARHGAP5	P06213	INSR	Y1091	P1087S	1087	Missense	distal	-4	no	17.232	19.366	EPSD	GDSC;CCLE	10.312	Up-regulation
TK_InsR_INSR_Y	Q13017	ARHGAP5	P06213	INSR	Y1091	I1095L	1095	Missense	distal	4	no	17.232	17.037	EPSD	GDSC;CCLE	10.312	Down-regulation
TK_InsR_INSR_Y	Q13017	ARHGAP5	P06213	INSR	Y1091	I1098V	1098	Missense	distal	7	no	17.232	17.235	EPSD	GDSC	10.312	Up-regulation
TK_InsR_INSR_Y	Q13017	ARHGAP5	P06213	INSR	Y1091	S1088L	1088	Missense	distal	-3	no	17.232	12.989	EPSD	GDSC;CCLE	10.312	Down-regulation
TK_InsR_INSR_Y	P29350	PTPN6	P06213	INSR	Y536	S534L	534	Missense	proximal	-2	no	17.447	12.141	PhosphoSitePlus	GDSC	10.312	Down-regulation
STE_STE-Unique_MAP3K8_ST	P35241	RDX	P41279	MAP3K8	T564	K563N	563	Missense	proximal	-1	no	27.578	28.301	PhosphoSitePlus	GDSC;CCLE	13.250	Up-regulation
STE_STE-Unique_MAP3K8_ST	P46734	MAP2K3	P41279	MAP3K8	S218	V216G	216	Missense	proximal	-2	no	35.996	36.266	PhosphoSitePlus	GDSC;CCLE	13.250	Up-regulation
STE_STE-Unique_MAP3K8_ST	P46734	MAP2K3	P41279	MAP3K8	S218	D217E	217	Missense	proximal	-1	no	35.996	33.175	PhosphoSitePlus	GDSC;CCLE	13.250	Down-regulation
STE_STE-Unique_MAP3K8_ST	P46734	MAP2K3	P41279	MAP3K8	T222	V216G	216	Missense	distal	-6	no	14.272	14.904	EPSD	GDSC;CCLE	13.250	Up-regulation
STE_STE-Unique_MAP3K8_ST	P46734	MAP2K3	P41279	MAP3K8	T222	D217E	217	Missense	distal	-5	no	14.272	14.254	EPSD	GDSC;CCLE	13.250	Down-regulation
STE_STE-Unique_MAP3K8_ST	P46734	MAP2K3	P41279	MAP3K8	T222	K228R	228	Missense	distal	6	no	14.272	15.583	EPSD	GDSC;CCLE	13.250	Up-regulation
STE_STE-Unique_MAP3K8_ST	Q14653	IRF3	P41279	MAP3K8	S97	A93V	93	Missense	distal	-4	no	13.211	13.262	EPSD	GDSC	13.250	Gain
STE_STE-Unique_MAP3K8_ST	P15311	EZR	P41279	MAP3K8	T533	R529W	529	Missense	distal	-4	no	20.836	21.238	EPSD	GDSC;CCLE	13.250	Up-regulation
STE_STE-Unique_MAP3K8_ST	P15311	EZR	P41279	MAP3K8	S536	R529W	529	Missense	distal	-7	no	16.296	15.739	EPSD	GDSC;CCLE	13.250	Down-regulation
STE_STE-Unique_MAP3K8_ST	P15311	EZR	P41279	MAP3K8	S539	N545S	545	Missense	distal	6	no	16.550	16.136	EPSD	GDSC;CCLE	13.250	Down-regulation
STE_STE-Unique_MAP3K8_ST	P15311	EZR	P41279	MAP3K8	T548	H549R	549	Missense	proximal	1	no	11.703	15.661	EPSD	GDSC;CCLE	13.250	Gain
STE_STE-Unique_MAP3K8_ST	P16220	CREB1	P41279	MAP3K8	T104	S111L	111	Missense	distal	7	no	19.334	18.069	EPSD	GDSC;CCLE	13.250	Down-regulation
STE_STE-Unique_MAP3K8_ST	P16220	CREB1	P41279	MAP3K8	S111	S111L	111	Missense	central	0	yes	13.478	0.000	EPSD	GDSC;CCLE	13.250	Loss
STE_STE-Unique_MAP3K8_ST	P16220	CREB1	P41279	MAP3K8	S114	S111L	111	Missense	distal	-3	no	12.820	16.798	EPSD	GDSC;CCLE	13.250	Gain
STE_STE-Unique_MAP3K8_ST	Q04637	EIF4G1	P41279	MAP3K8	S895	R893Q	893	Missense	proximal	-2	no	22.386	21.704	EPSD	GDSC;CCLE	13.250	Down-regulation
STE_STE-Unique_MAP3K8_ST	Q04637	EIF4G1	P41279	MAP3K8	S895	A891T	891	Missense	distal	-4	no	22.386	22.159	EPSD	GDSC;CCLE	13.250	Down-regulation
STE_STE-Unique_MAP3K8_ST	Q04637	EIF4G1	P41279	MAP3K8	S1077	K1074T	1074	Missense	distal	-3	no	18.640	10.703	EPSD	GDSC	13.250	Loss
STE_STE-Unique_MAP3K8_ST	Q04637	EIF4G1	P41279	MAP3K8	S1164	R1157Q	1157	Missense	distal	-7	no	15.969	15.639	EPSD	GDSC;CCLE	13.250	Down-regulation
STE_STE-Unique_MAP3K8_ST	Q04637	EIF4G1	P41279	MAP3K8	T1179	D1175V	1175	Missense	distal	-4	no	26.900	27.574	EPSD	GDSC;CCLE	13.250	Up-regulation
STE_STE-Unique_MAP3K8_ST	Q04637	EIF4G1	P41279	MAP3K8	T1182	D1175V	1175	Missense	distal	-7	no	16.543	16.393	EPSD	GDSC;CCLE	13.250	Down-regulation
STE_STE-Unique_MAP3K8_ST	Q04637	EIF4G1	P41279	MAP3K8	S1194	R1197Q	1197	Missense	distal	3	no	14.389	11.746	EPSD	GDSC	13.250	Loss
STE_STE-Unique_MAP3K8_ST	Q04637	EIF4G1	P41279	MAP3K8	T1495	R1498Q	1498	Missense	distal	3	no	14.057	11.413	EPSD	GDSC;CCLE	13.250	Loss
STE_STE-Unique_MAP3K8_ST	P52564	MAP2K6	P41279	MAP3K8	S207	S201G	201	Missense	distal	-6	no	36.275	35.752	PhosphoSitePlus	GDSC	13.250	Down-regulation
STE_STE-Unique_MAP3K8_ST	Q13541	EIF4EBP1	P41279	MAP3K8	T70	P66T	66	Missense	distal	-4	no	22.215	21.888	PhosphoSitePlus	GDSC	13.250	Down-regulation
STE_STE-Unique_MAP3K8_ST	P06493	CDK1	P41279	MAP3K8	S248	S248N	248	Missense	central	0	yes	14.692	0.000	EPSD	GDSC;CCLE	13.250	Loss
STE_STE-Unique_MAP3K8_ST	P36507	MAP2K2	P41279	MAP3K8	S222	S222C	222	Missense	central	0	yes	34.924	0.000	EPSD;PhosphoSitePlus	GDSC;CCLE	13.250	Loss
STE_STE-Unique_MAP3K8_ST	P36507	MAP2K2	P41279	MAP3K8	S226	S222C	222	Missense	distal	-4	no	29.977	30.693	PhosphoSitePlus;EPSD	GDSC;CCLE	13.250	Up-regulation
STE_STE-Unique_MAP3K8_ST	P06748	NPM1	P41279	MAP3K8	S214	P220L	220	Missense	distal	6	no	13.254	13.299	EPSD	GDSC;CCLE	13.250	Up-regulation
STE_STE-Unique_MAP3K8_ST	P06748	NPM1	P41279	MAP3K8	S214	N210S	210	Missense	distal	-4	no	13.254	13.419	EPSD	GDSC;CCLE	13.250	Up-regulation
STE_STE-Unique_MAP3K8_ST	P06748	NPM1	P41279	MAP3K8	T237	P235S	235	Missense	proximal	-2	no	17.397	17.936	EPSD	GDSC;CCLE	13.250	Up-regulation
CMGC_MAPK_JNK_MAPK9_ST	P46937	YAP1	P45984	MAPK9	T154	R161*	161	Missense	distal	7	no	159.726	160.607	PhosphoSitePlus;EPSD	GDSC	140.458	Up-regulation
CMGC_MAPK_JNK_MAPK9_ST	P46937	YAP1	P45984	MAPK9	S227	A228V	228	Missense	proximal	1	no	147.497	-12.184	EPSD	GDSC;CCLE	140.458	Loss
CMGC_MAPK_JNK_MAPK9_ST	P46937	YAP1	P45984	MAPK9	S340	A347S	347	Missense	distal	7	no	159.000	159.305	EPSD	GDSC	140.458	Up-regulation
CMGC_MAPK_JNK_MAPK9_ST	P46937	YAP1	P45984	MAPK9	S382	D383A	383	Missense	proximal	1	no	141.944	138.707	EPSD	GDSC;CCLE	140.458	Loss
CMGC_MAPK_JNK_MAPK9_ST	O43602	DCX	P45984	MAPK9	T289	S287T	287	Missense	proximal	-2	no	157.792	157.916	EPSD	GDSC	140.458	Up-regulation
CMGC_MAPK_JNK_MAPK9_ST	P10636	MAPT	P45984	MAPK9	S46	Q49H	49	Missense	distal	3	no	146.918	146.671	EPSD	GDSC	140.458	Down-regulation
CMGC_MAPK_JNK_MAPK9_ST	P10636	MAPT	P45984	MAPK9	S46	A41V	41	Missense	distal	-5	no	146.918	146.982	EPSD	GDSC;CCLE	140.458	Up-regulation
CMGC_MAPK_JNK_MAPK9_ST	P10636	MAPT	P45984	MAPK9	T50	Q49H	49	Missense	proximal	-1	no	156.013	155.794	EPSD	GDSC	140.458	Down-regulation
CMGC_MAPK_JNK_MAPK9_ST	P10636	MAPT	P45984	MAPK9	S228	R222H	222	Missense	distal	-6	no	156.450	156.009	EPSD	GDSC;CCLE	140.458	Down-regulation
CMGC_MAPK_JNK_MAPK9_ST	P10636	MAPT	P45984	MAPK9	T470	A475V	475	Missense	distal	5	no	149.411	149.828	EPSD	GDSC;CCLE	140.458	Up-regulation
CMGC_MAPK_JNK_MAPK9_ST	P10636	MAPT	P45984	MAPK9	S739	S739C	739	Missense	central	0	yes	150.893	0.000	EPSD	GDSC	140.458	Loss
CMGC_MAPK_JNK_MAPK9_ST	P15336	ATF2	P45984	MAPK9	S62	V63A	63	Missense	proximal	1	no	-18.028	141.653	EPSD	GDSC;CCLE	140.458	Gain
CMGC_MAPK_JNK_MAPK9_ST	P15336	ATF2	P45984	MAPK9	T69	V63A	63	Missense	distal	-6	no	157.619	157.939	PhosphoSitePlus;EPSD	GDSC;CCLE	140.458	Up-regulation
CMGC_MAPK_JNK_MAPK9_ST	P15336	ATF2	P45984	MAPK9	T131	Q134H	134	Missense	distal	3	no	141.821	141.574	EPSD	GDSC;CCLE	140.458	Down-regulation
CMGC_MAPK_JNK_MAPK9_ST	P15336	ATF2	P45984	MAPK9	S136	Q134H	134	Missense	proximal	-2	no	153.807	150.978	EPSD	GDSC;CCLE	140.458	Down-regulation
CMGC_MAPK_JNK_MAPK9_ST	P15336	ATF2	P45984	MAPK9	T325	H331L	331	Missense	distal	6	no	157.279	157.274	EPSD	GDSC;CCLE	140.458	Down-regulation
CMGC_MAPK_JNK_MAPK9_ST	P15336	ATF2	P45984	MAPK9	S328	H331L	331	Missense	distal	3	no	160.859	160.713	EPSD	GDSC;CCLE	140.458	Down-regulation
CMGC_MAPK_JNK_MAPK9_ST	P15336	ATF2	P45984	MAPK9	T333	H331L	331	Missense	proximal	-2	no	152.446	155.402	EPSD	GDSC;CCLE	140.458	Up-regulation
CMGC_MAPK_JNK_MAPK9_ST	P15336	ATF2	P45984	MAPK9	S338	R342H	342	Missense	distal	4	no	141.803	142.084	EPSD	GDSC;CCLE	140.458	Up-regulation
CMGC_MAPK_JNK_MAPK9_ST	P15336	ATF2	P45984	MAPK9	S338	H331L	331	Missense	distal	-7	no	141.803	140.809	EPSD	GDSC;CCLE	140.458	Down-regulation
CMGC_MAPK_JNK_MAPK9_ST	P05067	APP	P45984	MAPK9	T381	H388Y	388	Missense	distal	7	no	152.510	153.096	EPSD	GDSC;CCLE	140.458	Up-regulation
CMGC_MAPK_JNK_MAPK9_ST	P38936	CDKN1A	P45984	MAPK9	T57	E56*	56	Missense	proximal	-1	no	162.997	162.686	EPSD;PhosphoSitePlus	GDSC	140.458	Down-regulation
CMGC_MAPK_JNK_MAPK9_ST	P38936	CDKN1A	P45984	MAPK9	S137	R143Q	143	Missense	distal	6	no	140.385	140.553	EPSD	GDSC;CCLE	140.458	Gain
CMGC_MAPK_JNK_MAPK9_ST	P19793	RXRA	P45984	MAPK9	S21	R25*	25	Missense	distal	4	no	156.099	156.539	EPSD	GDSC	140.458	Up-regulation
CMGC_MAPK_JNK_MAPK9_ST	P19793	RXRA	P45984	MAPK9	S21	P22L	22	Missense	proximal	1	no	156.099	111.196	EPSD	GDSC	140.458	Loss
CMGC_MAPK_JNK_MAPK9_ST	P50616	TOB1	P45984	MAPK9	S152	H159Y	159	Missense	distal	7	no	159.585	160.170	EPSD;PhosphoSitePlus	GDSC;CCLE	140.458	Up-regulation
CMGC_MAPK_JNK_MAPK9_ST	P50616	TOB1	P45984	MAPK9	S154	H159Y	159	Missense	distal	5	no	161.569	162.172	PhosphoSitePlus;EPSD	GDSC;CCLE	140.458	Up-regulation
CMGC_MAPK_JNK_MAPK9_ST	P50616	TOB1	P45984	MAPK9	S164	H159Y	159	Missense	distal	-5	no	161.971	162.052	EPSD;PhosphoSitePlus	GDSC;CCLE	140.458	Up-regulation
CMGC_MAPK_JNK_MAPK9_ST	Q07817	BCL2L1	P45984	MAPK9	T47	S43L	43	Missense	distal	-4	no	161.645	159.453	PhosphoSitePlus;EPSD	GDSC;CCLE	140.458	Down-regulation
CMGC_MAPK_JNK_MAPK9_ST	Q07817	BCL2L1	P45984	MAPK9	S62	P55S	55	Missense	distal	-7	no	156.992	158.023	EPSD;PhosphoSitePlus	GDSC;CCLE	140.458	Up-regulation
CMGC_MAPK_JNK_MAPK9_ST	Q07817	BCL2L1	P45984	MAPK9	S62	T69I	69	Missense	distal	7	no	156.992	156.928	EPSD;PhosphoSitePlus	GDSC;CCLE	140.458	Down-regulation
CMGC_MAPK_JNK_MAPK9_ST	Q07817	BCL2L1	P45984	MAPK9	S62	G67V	67	Missense	distal	5	no	156.992	156.844	EPSD;PhosphoSitePlus	GDSC;CCLE	140.458	Down-regulation
CMGC_MAPK_JNK_MAPK9_ST	Q14934	NFATC4	P45984	MAPK9	S237	S237N	237	Missense	central	0	yes	153.704	0.000	EPSD	GDSC	140.458	Loss
CMGC_MAPK_JNK_MAPK9_ST	Q9UGP4	LIMD1	P45984	MAPK9	S160	P165L	165	Missense	distal	5	no	140.015	140.784	EPSD	GDSC;CCLE	140.458	Gain
CMGC_MAPK_JNK_MAPK9_ST	Q9UGP4	LIMD1	P45984	MAPK9	S197	G195R	195	Missense	proximal	-2	no	146.722	149.387	EPSD	GDSC;CCLE	140.458	Up-regulation
CMGC_MAPK_JNK_MAPK9_ST	Q9UGP4	LIMD1	P45984	MAPK9	T294	V290F	290	Missense	distal	-4	no	159.787	157.606	EPSD	GDSC;CCLE	140.458	Down-regulation
CMGC_MAPK_JNK_MAPK9_ST	Q9UGP4	LIMD1	P45984	MAPK9	T375	G369E	369	Missense	distal	-6	no	140.658	141.003	EPSD	GDSC;CCLE	140.458	Up-regulation
CMGC_MAPK_JNK_MAPK9_ST	Q12968	NFATC3	P45984	MAPK9	S163	R158Q	158	Missense	distal	-5	no	158.558	158.541	EPSD;PhosphoSitePlus	GDSC;CCLE	140.458	Down-regulation
CMGC_MAPK_JNK_MAPK9_ST	Q12968	NFATC3	P45984	MAPK9	S163	S168N	168	Missense	distal	5	no	158.558	158.328	EPSD;PhosphoSitePlus	GDSC;CCLE	140.458	Down-regulation
CMGC_MAPK_JNK_MAPK9_ST	Q12968	NFATC3	P45984	MAPK9	S165	R158Q	158	Missense	distal	-7	no	161.917	161.844	PhosphoSitePlus;EPSD	GDSC;CCLE	140.458	Down-regulation
CMGC_MAPK_JNK_MAPK9_ST	Q12968	NFATC3	P45984	MAPK9	S165	S168N	168	Missense	distal	3	no	161.917	162.045	PhosphoSitePlus;EPSD	GDSC;CCLE	140.458	Up-regulation
CMGC_MAPK_JNK_MAPK9_ST	Q12968	NFATC3	P45984	MAPK9	S177	S177F	177	Missense	central	0	yes	146.357	0.000	EPSD	GDSC;CCLE	140.458	Loss
CMGC_MAPK_JNK_MAPK9_ST	Q12968	NFATC3	P45984	MAPK9	S236	G230E	230	Missense	distal	-6	no	143.131	143.475	EPSD	GDSC;CCLE	140.458	Up-regulation
CMGC_MAPK_JNK_MAPK9_ST	Q12968	NFATC3	P45984	MAPK9	T409	S416P	416	Missense	distal	7	no	155.812	155.583	EPSD	GDSC;CCLE	140.458	Down-regulation
CMGC_MAPK_JNK_MAPK9_ST	Q12968	NFATC3	P45984	MAPK9	S415	S416P	416	Missense	proximal	1	no	-126.178	154.616	EPSD	GDSC;CCLE	140.458	Gain
CMGC_MAPK_JNK_MAPK9_ST	Q12968	NFATC3	P45984	MAPK9	S546	R551*	551	Missense	distal	5	no	144.036	145.056	EPSD	GDSC	140.458	Up-regulation
CMGC_MAPK_JNK_MAPK9_ST	Q12968	NFATC3	P45984	MAPK9	T698	E705*	705	Missense	distal	7	no	147.737	148.333	EPSD	GDSC	140.458	Up-regulation
CMGC_MAPK_JNK_MAPK9_ST	P05412	JUN	P45984	MAPK9	T91	H87R	87	Missense	distal	-4	no	158.955	160.595	EPSD	GDSC;CCLE	140.458	Up-regulation
CMGC_MAPK_JNK_MAPK9_ST	P05412	JUN	P45984	MAPK9	T93	H87R	87	Missense	distal	-6	no	155.827	156.268	EPSD	GDSC;CCLE	140.458	Up-regulation
CMGC_MAPK_JNK_MAPK9_ST	P05412	JUN	P45984	MAPK9	T239	E234D	234	Missense	distal	-5	no	156.287	156.392	EPSD	GDSC;CCLE	140.458	Up-regulation
CMGC_MAPK_JNK_MAPK9_ST	P05412	JUN	P45984	MAPK9	S296	Q290*	290	Missense	distal	-6	no	141.410	140.837	EPSD	GDSC	140.458	Down-regulation
CMGC_MAPK_JNK_MAPK9_ST	P04637	TP53	P45984	MAPK9	S33	Q38*	38	Missense	distal	5	no	154.719	155.530	EPSD	GDSC	140.458	Up-regulation
CMGC_MAPK_JNK_MAPK9_ST	P04637	TP53	P45984	MAPK9	S37	Q38*	38	Missense	proximal	1	no	140.751	-47.580	EPSD	GDSC	140.458	Loss
CMGC_MAPK_JNK_MAPK9_ST	P04637	TP53	P45984	MAPK9	T81	A74S	74	Missense	distal	-7	no	166.507	165.387	EPSD	GDSC;CCLE	140.458	Down-regulation
CMGC_MAPK_JNK_MAPK9_ST	P04637	TP53	P45984	MAPK9	S99	K101*	101	Missense	proximal	2	no	140.696	140.876	EPSD	GDSC	140.458	Up-regulation
CMGC_MAPK_JNK_MAPK9_ST	P04637	TP53	P45984	MAPK9	S99	Q100*	100	Missense	proximal	1	no	140.696	-47.636	EPSD	GDSC	140.458	Loss
CMGC_MAPK_JNK_MAPK9_ST	P04637	TP53	P45984	MAPK9	S99	S94*	94	Missense	distal	-5	no	140.696	140.782	EPSD	GDSC	140.458	Up-regulation
CMGC_MAPK_JNK_MAPK9_ST	P04637	TP53	P45984	MAPK9	S127	Y126*	126	Missense	proximal	-1	no	145.026	145.151	EPSD	GDSC	140.458	Up-regulation
CMGC_MAPK_JNK_MAPK9_ST	P04637	TP53	P45984	MAPK9	S127	K120*	120	Missense	distal	-7	no	145.026	143.062	EPSD	GDSC	140.458	Down-regulation
CMGC_MAPK_JNK_MAPK9_ST	P04637	TP53	P45984	MAPK9	T150	Q144*	144	Missense	distal	-6	no	153.234	152.661	EPSD	GDSC	140.458	Down-regulation
CMGC_MAPK_JNK_MAPK9_ST	P04637	TP53	P45984	MAPK9	T150	W146*	146	Missense	distal	-4	no	153.234	154.726	EPSD	GDSC	140.458	Up-regulation
CMGC_MAPK_JNK_MAPK9_ST	P04637	TP53	P45984	MAPK9	S183	S183*	183	Missense	central	0	yes	144.606	0.000	EPSD	GDSC	140.458	Loss
CMGC_MAPK_JNK_MAPK9_ST	P04637	TP53	P45984	MAPK9	S183	E180*	180	Missense	distal	-3	no	144.606	142.280	EPSD	GDSC	140.458	Down-regulation
CMGC_MAPK_JNK_MAPK9_ST	P04637	TP53	P45984	MAPK9	S315	Q317*	317	Missense	proximal	2	no	155.450	155.661	EPSD	GDSC	140.458	Up-regulation
CMGC_MAPK_JNK_MAPK9_ST	P04637	TP53	P45984	MAPK9	S315	K319*	319	Missense	distal	4	no	155.450	155.762	EPSD	GDSC	140.458	Up-regulation
CMGC_MAPK_JNK_MAPK9_ST	Q9UIG0	BAZ1B	P45984	MAPK9	S46	W50*	50	Missense	distal	4	no	142.052	141.948	EPSD	GDSC	140.458	Down-regulation
CMGC_MAPK_JNK_MAPK9_ST	Q9UIG0	BAZ1B	P45984	MAPK9	S197	T203A	203	Missense	distal	6	no	161.590	162.002	EPSD	GDSC;CCLE	140.458	Up-regulation
CMGC_MAPK_JNK_MAPK9_ST	Q9UIG0	BAZ1B	P45984	MAPK9	S330	L332V	332	Missense	proximal	2	no	156.612	156.608	EPSD	GDSC;CCLE	140.458	Down-regulation
CMGC_MAPK_JNK_MAPK9_ST	Q9UIG0	BAZ1B	P45984	MAPK9	S423	K425R	425	Missense	proximal	2	no	150.878	150.802	EPSD	GDSC	140.458	Down-regulation
CMGC_MAPK_JNK_MAPK9_ST	Q9UIG0	BAZ1B	P45984	MAPK9	T430	K425R	425	Missense	distal	-5	no	156.033	156.023	EPSD	GDSC	140.458	Down-regulation
CMGC_MAPK_JNK_MAPK9_ST	Q9UIG0	BAZ1B	P45984	MAPK9	S708	D711H	711	Missense	distal	3	no	145.957	145.954	EPSD	GDSC;CCLE	140.458	Down-regulation
CMGC_MAPK_JNK_MAPK9_ST	Q9UIG0	BAZ1B	P45984	MAPK9	S716	D711H	711	Missense	distal	-5	no	141.426	141.401	EPSD	GDSC;CCLE	140.458	Down-regulation
CMGC_MAPK_JNK_MAPK9_ST	P30307	CDC25C	P45984	MAPK9	S247	G248D	248	Missense	proximal	1	no	-18.305	142.179	EPSD	GDSC	140.458	Gain
CMGC_MAPK_JNK_MAPK9_ST	P30307	CDC25C	P45984	MAPK9	S472	M471T	471	Missense	proximal	-1	no	161.346	161.042	EPSD	GDSC;CCLE	140.458	Down-regulation
CMGC_MAPK_JNK_MAPK9_ST	P31645	SLC6A4	P45984	MAPK9	S52	N45S	45	Missense	distal	-7	no	155.179	153.293	EPSD	GDSC;CCLE	140.458	Down-regulation
CMGC_MAPK_JNK_MAPK9_ST	P31645	SLC6A4	P45984	MAPK9	S52	S48L	48	Missense	distal	-4	no	155.179	152.988	EPSD	GDSC;CCLE	140.458	Down-regulation
CMGC_MAPK_JNK_MAPK9_ST	Q8IW41	MAPKAPK5	P45984	MAPK9	S212	P213Q	213	Missense	proximal	1	no	161.944	141.832	EPSD	GDSC;CCLE	140.458	Down-regulation
CMGC_MAPK_JNK_MAPK9_ST	Q8IW41	MAPKAPK5	P45984	MAPK9	S212	P215S	215	Missense	distal	3	no	161.944	161.896	EPSD	GDSC;CCLE	140.458	Down-regulation
CMGC_MAPK_JNK_MAPK9_ST	Q8IW41	MAPKAPK5	P45984	MAPK9	T214	P213Q	213	Missense	proximal	-1	no	156.012	155.987	EPSD	GDSC;CCLE	140.458	Down-regulation
CMGC_MAPK_JNK_MAPK9_ST	Q8IW41	MAPKAPK5	P45984	MAPK9	T214	P215S	215	Missense	proximal	1	no	156.012	-124.782	EPSD	GDSC;CCLE	140.458	Loss
CMGC_MAPK_JNK_MAPK9_ST	P29966	MARCKS	P45984	MAPK9	S308	P313L	313	Missense	distal	5	no	145.391	146.160	EPSD	GDSC	140.458	Up-regulation
CMGC_MAPK_JNK_MAPK9_ST	P29966	MARCKS	P45984	MAPK9	S308	A303T	303	Missense	distal	-5	no	145.391	145.429	EPSD	GDSC;CCLE	140.458	Up-regulation
CMGC_MAPK_JNK_MAPK9_ST	P29966	MARCKS	P45984	MAPK9	S314	P313L	313	Missense	proximal	-1	no	145.133	144.977	EPSD	GDSC	140.458	Down-regulation
CMGC_MAPK_JNK_MAPK9_ST	Q15750	TAB1	P45984	MAPK9	S339	R333W	333	Missense	distal	-6	no	144.136	143.330	EPSD	GDSC;CCLE	140.458	Down-regulation
CMGC_MAPK_JNK_MAPK9_ST	Q9UQF2	MAPK8IP1	P45984	MAPK9	S235	D234N	234	Missense	proximal	-1	no	153.307	153.619	EPSD	GDSC	140.458	Up-regulation
CMGC_MAPK_JNK_MAPK9_ST	Q9UQF2	MAPK8IP1	P45984	MAPK9	T241	D234N	234	Missense	distal	-7	no	138.738	141.156	EPSD	GDSC	140.458	Gain
CMGC_MAPK_JNK_MAPK9_ST	Q9UQF2	MAPK8IP1	P45984	MAPK9	T284	A277T	277	Missense	distal	-7	no	151.662	149.119	EPSD	GDSC	140.458	Down-regulation
CMGC_MAPK_JNK_MAPK9_ST	Q9UQF2	MAPK8IP1	P45984	MAPK9	S311	V309F	309	Missense	proximal	-2	no	141.853	140.097	EPSD	GDSC;CCLE	140.458	Loss
CMGC_MAPK_JNK_MAPK9_ST	Q9UQF2	MAPK8IP1	P45984	MAPK9	S421	D414E	414	Missense	distal	-7	no	145.512	146.945	EPSD	GDSC;CCLE	140.458	Up-regulation
CMGC_MAPK_JNK_MAPK9_ST	Q9UQF2	MAPK8IP1	P45984	MAPK9	S447	E451K	451	Missense	distal	4	no	143.353	143.451	EPSD	GDSC;CCLE	140.458	Up-regulation
CMGC_MAPK_JNK_MAPK9_ST	Q9UQF2	MAPK8IP1	P45984	MAPK9	T448	E451K	451	Missense	distal	3	no	164.131	164.085	EPSD	GDSC;CCLE	140.458	Down-regulation
CMGC_MAPK_JNK_MAPK9_ST	P98177	FOXO4	P45984	MAPK9	T451	T458A	458	Missense	distal	7	no	160.311	159.713	EPSD;PhosphoSitePlus	GDSC;CCLE	140.458	Down-regulation
CMGC_MAPK_JNK_MAPK9_ST	P98177	FOXO4	P45984	MAPK9	T451	T455I	455	Missense	distal	4	no	160.311	160.405	EPSD;PhosphoSitePlus	GDSC;CCLE	140.458	Up-regulation
CMGC_MAPK_JNK_MAPK9_ST	P98177	FOXO4	P45984	MAPK9	T455	T458A	458	Missense	distal	3	no	161.686	161.897	PhosphoSitePlus;EPSD	GDSC;CCLE	140.458	Up-regulation
CMGC_MAPK_JNK_MAPK9_ST	P98177	FOXO4	P45984	MAPK9	T455	T455I	455	Missense	central	0	yes	161.686	0.000	PhosphoSitePlus;EPSD	GDSC;CCLE	140.458	Loss
CMGC_MAPK_JNK_MAPK9_ST	Q9NYV6	RRN3	P45984	MAPK9	S44	F41I	41	Missense	distal	-3	no	152.328	154.224	EPSD	GDSC	140.458	Up-regulation
CMGC_MAPK_JNK_MAPK9_ST	Q9NYV6	RRN3	P45984	MAPK9	S170	D176N	176	Missense	distal	6	no	144.726	145.192	EPSD	GDSC;CCLE	140.458	Up-regulation
CMGC_MAPK_JNK_MAPK9_ST	Q9NYV6	RRN3	P45984	MAPK9	T200	W202L	202	Missense	proximal	2	no	157.330	157.184	PhosphoSitePlus	GDSC;CCLE	140.458	Down-regulation
CMGC_MAPK_JNK_MAPK9_ST	Q9NYV6	RRN3	P45984	MAPK9	T623	P624Q	624	Missense	proximal	1	no	155.505	135.393	EPSD	GDSC;CCLE	140.458	Loss
AGC_NDR_LATS_LATS2_ST	Q9NQS7	INCENP	Q9NRM7	LATS2	S197	R194C	194	Missense	distal	-3	no	0.051	0.003	EPSD	GDSC	0.004	Loss
AGC_NDR_LATS_LATS2_ST	Q9NQS7	INCENP	Q9NRM7	LATS2	T298	P293H	293	Missense	distal	-5	no	-0.003	0.008	EPSD	GDSC;CCLE	0.004	Gain
AGC_NDR_LATS_LATS2_ST	Q9NQS7	INCENP	Q9NRM7	LATS2	S336	R338K	338	Missense	proximal	2	no	0.047	0.048	EPSD	GDSC;CCLE	0.004	Up-regulation
AGC_NDR_LATS_LATS2_ST	Q9NQS7	INCENP	Q9NRM7	LATS2	S373	E366Q	366	Missense	distal	-7	no	0.003	0.004	EPSD	GDSC;CCLE	0.004	Gain
AGC_NDR_LATS_LATS2_ST	P38936	CDKN1A	Q9NRM7	LATS2	S114	L119R	119	Missense	distal	5	no	0.006	0.005	EPSD	GDSC;CCLE	0.004	Down-regulation
AGC_NDR_LATS_LATS2_ST	P38936	CDKN1A	Q9NRM7	LATS2	S146	R143Q	143	Missense	distal	-3	no	0.054	0.005	PhosphoSitePlus	GDSC;CCLE	0.004	Down-regulation
AGC_NDR_LATS_LATS2_ST	P00519	ABL1	Q9NRM7	LATS2	T844	P845S	845	Missense	proximal	1	no	0.005	0.004	EPSD	GDSC	0.004	Down-regulation
AGC_NDR_LATS_LATS2_ST	P46937	YAP1	Q9NRM7	LATS2	S103	P98L	98	Missense	distal	-5	no	0.003	0.004	EPSD	GDSC;CCLE	0.004	Gain
AGC_NDR_LATS_LATS2_ST	P46937	YAP1	Q9NRM7	LATS2	S164	R161*	161	Missense	distal	-3	no	0.064	0.017	EPSD;PhosphoSitePlus	GDSC	0.004	Down-regulation
AGC_NDR_LATS_LATS2_ST	Q9Y2J4	AMOTL2	Q9NRM7	LATS2	S180	H177R	177	Missense	distal	-3	no	-0.004	0.046	EPSD	GDSC;CCLE	0.004	Gain
AGC_NDR_LATS_LATS2_ST	Q9Y2J4	AMOTL2	Q9NRM7	LATS2	S606	R600*	600	Missense	distal	-6	no	0.009	0.010	EPSD	GDSC	0.004	Up-regulation
AGC_NDR_LATS_LATS2_ST	Q9Y2J4	AMOTL2	Q9NRM7	LATS2	S606	H601Q	601	Missense	distal	-5	no	0.009	-0.002	EPSD	GDSC	0.004	Loss
AGC_NDR_LATS_LATS2_ST	Q9Y2J4	AMOTL2	Q9NRM7	LATS2	S609	Q604H	604	Missense	distal	-5	no	-0.001	0.010	EPSD	GDSC	0.004	Gain
AGC_NDR_LATS_LATS2_ST	Q4VCS5	AMOT	Q9NRM7	LATS2	T709	T709A	709	Missense	central	0	yes	0.047	0.000	EPSD	GDSC;CCLE	0.004	Loss
AGC_NDR_LATS_LATS2_ST	Q4VCS5	AMOT	Q9NRM7	LATS2	S712	D707H	707	Missense	distal	-5	no	0.000	0.010	EPSD	GDSC	0.004	Gain
AGC_NDR_LATS_LATS2_ST	Q9GZV5	WWTR1	Q9NRM7	LATS2	S89	S89L	89	Missense	central	0	yes	0.071	0.000	PhosphoSitePlus	GDSC;CCLE	0.004	Loss
AGC_NDR_LATS_LATS2_ST	Q9GZV5	WWTR1	Q9NRM7	LATS2	S117	S117P	117	Missense	central	0	yes	0.059	0.000	EPSD	GDSC;CCLE	0.004	Loss
Other_CAMKK_CAMKK-Meta_CAMKK2_ST	Q96EB6	SIRT1	Q96RR4	CAMKK2	S525	E520*	520	Missense	distal	-5	no	21.110	18.493	EPSD	GDSC	15.642	Down-regulation
Other_CAMKK_CAMKK-Meta_CAMKK2_ST	Q96RR4	CAMKK2	Q96RR4	CAMKK2	T350	S345F	345	Missense	distal	-5	no	18.401	15.787	EPSD	GDSC;CCLE	15.642	Down-regulation
Other_CAMKK_CAMKK-Meta_CAMKK2_ST	Q96RR4	CAMKK2	Q96RR4	CAMKK2	T350	P351L	351	Missense	proximal	1	no	18.401	13.281	EPSD	GDSC;CCLE	15.642	Loss
Other_CAMKK_CAMKK-Meta_CAMKK2_ST	Q96RR4	CAMKK2	Q96RR4	CAMKK2	S511	R508C	508	Missense	distal	-3	no	15.890	15.871	EPSD	GDSC	15.642	Down-regulation
Other_CAMKK_CAMKK-Meta_CAMKK2_ST	P54646	PRKAA2	Q96RR4	CAMKK2	S481	T485A	485	Missense	distal	4	no	21.659	20.979	EPSD	GDSC;CCLE	15.642	Down-regulation
Other_CAMKK_CAMKK-Meta_CAMKK2_ST	P31749	AKT1	Q96RR4	CAMKK2	T308	K307N	307	Missense	proximal	-1	no	41.175	41.023	PhosphoSitePlus	GDSC;CCLE	15.642	Down-regulation
TK_FGFR_FGFR1_Y	P11362	FGFR1	P11362	FGFR1	Y730	T726I	726	Missense	distal	-4	no	7.496	7.700	EPSD;PhosphoSitePlus	GDSC;CCLE	5.471	Up-regulation
TK_FGFR_FGFR1_Y	P11362	FGFR1	P11362	FGFR1	Y766	D768N	768	Missense	proximal	2	no	7.865	7.668	EPSD;PhosphoSitePlus	GDSC;CCLE	5.471	Down-regulation
TK_FGFR_FGFR1_Y	Q9UBW7	ZMYM2	P11362	FGFR1	Y502	P509A	509	Missense	distal	7	no	7.710	8.194	EPSD;PhosphoSitePlus	GDSC;CCLE	5.471	Up-regulation
TK_FGFR_FGFR1_Y	Q9UBW7	ZMYM2	P11362	FGFR1	Y502	H508Y	508	Missense	distal	6	no	7.710	7.708	EPSD;PhosphoSitePlus	GDSC;CCLE	5.471	Down-regulation
TK_FGFR_FGFR1_Y	Q9UBW7	ZMYM2	P11362	FGFR1	Y605	N609S	609	Missense	distal	4	no	10.063	10.703	EPSD;PhosphoSitePlus	GDSC;CCLE	5.471	Up-regulation
TK_FGFR_FGFR1_Y	Q9P0J1	PDP1	P11362	FGFR1	Y381	N379D	379	Missense	proximal	-2	no	7.437	7.461	PhosphoSitePlus	GDSC;CCLE	5.471	Up-regulation
TK_FGFR_FGFR1_Y	Q15118	PDK1	P11362	FGFR1	Y243	I245S	245	Missense	proximal	2	no	8.210	8.336	EPSD;PhosphoSitePlus	GDSC	5.471	Up-regulation
TK_FGFR_FGFR1_Y	P00338	LDHA	P11362	FGFR1	Y10	D6H	6	Missense	distal	-4	no	5.782	6.058	PhosphoSitePlus;EPSD	GDSC;CCLE	5.471	Up-regulation
AGC_GRK_BARK_GRK3_ST	P30874	SSTR2	P35626	GRK3	S341	G334S	334	Missense	distal	-7	no	7.870	9.978	PhosphoSitePlus;EPSD	GDSC;CCLE	9.327	Gain
AGC_SGK_SGK3_ST	Q13045	FLII	Q96BR1	SGK3	T818	A817T	817	Missense	proximal	-1	no	9.197	9.520	EPSD;PhosphoSitePlus	GDSC	2.112	Up-regulation
AGC_SGK_SGK3_ST	P49841	GSK3B	Q96BR1	SGK3	T7	T8P	8	Missense	proximal	1	no	4.624	4.649	EPSD	GDSC	2.112	Up-regulation
AGC_SGK_SGK3_ST	P49841	GSK3B	Q96BR1	SGK3	S9	T8P	8	Missense	proximal	-1	no	8.615	7.842	PhosphoSitePlus	GDSC	2.112	Down-regulation
Atypical_PIKK_ATM_ATM_ST	P25205	MCM3	Q13315	ATM	S160	A167S	167	Missense	distal	7	no	9.879	9.848	EPSD	GDSC;CCLE	9.540	Down-regulation
Atypical_PIKK_ATM_ATM_ST	P25205	MCM3	Q13315	ATM	T542	K547Q	547	Missense	distal	5	no	10.063	10.112	EPSD	GDSC;CCLE	9.540	Up-regulation
Atypical_PIKK_ATM_ATM_ST	P25205	MCM3	Q13315	ATM	S704	S704P	704	Missense	central	0	yes	10.159	0.000	EPSD	GDSC;CCLE	9.540	Loss
Atypical_PIKK_ATM_ATM_ST	P25205	MCM3	Q13315	ATM	S728	T725M	725	Missense	distal	-3	no	16.571	16.994	EPSD	GDSC;CCLE	9.540	Up-regulation
Atypical_PIKK_ATM_ATM_ST	P25205	MCM3	Q13315	ATM	S734	E741K	741	Missense	distal	7	no	13.918	13.945	EPSD	GDSC;CCLE	9.540	Up-regulation
Atypical_PIKK_ATM_ATM_ST	P25205	MCM3	Q13315	ATM	S740	E741K	741	Missense	proximal	1	no	10.988	10.036	EPSD	GDSC;CCLE	9.540	Down-regulation
Atypical_PIKK_ATM_ATM_ST	Q9NVI1	FANCI	Q13315	ATM	S565	D570A	570	Missense	distal	5	no	13.688	13.649	EPSD	GDSC;CCLE	9.540	Down-regulation
Atypical_PIKK_ATM_ATM_ST	Q9NVI1	FANCI	Q13315	ATM	T653	I658M	658	Missense	distal	5	no	10.521	10.496	EPSD	GDSC;CCLE	9.540	Down-regulation
Atypical_PIKK_ATM_ATM_ST	Q9NVI1	FANCI	Q13315	ATM	S726	S726P	726	Missense	central	0	yes	11.387	0.000	EPSD	GDSC	9.540	Loss
Atypical_PIKK_ATM_ATM_ST	Q9NVI1	FANCI	Q13315	ATM	S726	F729I	729	Missense	distal	3	no	11.387	11.306	EPSD	GDSC;CCLE	9.540	Down-regulation
Atypical_PIKK_ATM_ATM_ST	Q9NVI1	FANCI	Q13315	ATM	S730	S726P	726	Missense	distal	-4	no	16.945	16.276	EPSD;PhosphoSitePlus	GDSC	9.540	Down-regulation
Atypical_PIKK_ATM_ATM_ST	Q9NVI1	FANCI	Q13315	ATM	S730	F729I	729	Missense	proximal	-1	no	16.945	17.151	EPSD;PhosphoSitePlus	GDSC;CCLE	9.540	Up-regulation
Atypical_PIKK_ATM_ATM_ST	Q9NVI1	FANCI	Q13315	ATM	T952	S950C	950	Missense	proximal	-2	no	10.846	10.385	EPSD	GDSC;CCLE	9.540	Down-regulation
Atypical_PIKK_ATM_ATM_ST	Q9NVI1	FANCI	Q13315	ATM	S1121	Q1122R	1122	Missense	proximal	1	no	15.858	9.207	EPSD;PhosphoSitePlus	GDSC;CCLE	9.540	Loss
Atypical_PIKK_ATM_ATM_ST	Q9NVI1	FANCI	Q13315	ATM	S1312	G1315R	1315	Missense	distal	3	no	10.278	10.333	EPSD	GDSC;CCLE	9.540	Up-regulation
Atypical_PIKK_ATM_ATM_ST	Q9NVI1	FANCI	Q13315	ATM	S1312	Q1317*	1317	Missense	distal	5	no	10.278	10.709	EPSD	GDSC	9.540	Up-regulation
Atypical_PIKK_ATM_ATM_ST	O60934	NBN	Q13315	ATM	S58	T60K	60	Missense	proximal	2	no	16.155	15.597	EPSD	GDSC;CCLE	9.540	Down-regulation
Atypical_PIKK_ATM_ATM_ST	O60934	NBN	Q13315	ATM	S343	E350G	350	Missense	distal	7	no	15.318	15.363	PhosphoSitePlus;EPSD	GDSC;CCLE	9.540	Up-regulation
Atypical_PIKK_ATM_ATM_ST	O60934	NBN	Q13315	ATM	S397	F393L	393	Missense	distal	-4	no	13.676	14.136	EPSD;PhosphoSitePlus	GDSC;CCLE	9.540	Up-regulation
Atypical_PIKK_ATM_ATM_ST	O60934	NBN	Q13315	ATM	S447	Q448*	448	Missense	proximal	1	no	13.287	1.763	EPSD	GDSC	9.540	Loss
Atypical_PIKK_ATM_ATM_ST	O60934	NBN	Q13315	ATM	S447	Q448R	448	Missense	proximal	1	no	13.287	6.636	EPSD	GDSC;CCLE	9.540	Loss
Atypical_PIKK_ATM_ATM_ST	O60934	NBN	Q13315	ATM	S612	K613E	613	Missense	proximal	1	no	9.079	10.031	EPSD	GDSC;CCLE	9.540	Gain
Atypical_PIKK_ATM_ATM_ST	O60934	NBN	Q13315	ATM	S615	K613E	613	Missense	proximal	-2	no	14.474	15.050	EPSD;PhosphoSitePlus	GDSC;CCLE	9.540	Up-regulation
Atypical_PIKK_ATM_ATM_ST	O60934	NBN	Q13315	ATM	S673	P672Q	672	Missense	proximal	-1	no	9.535	9.760	EPSD	GDSC;CCLE	9.540	Gain
Atypical_PIKK_ATM_ATM_ST	P78527	PRKDC	Q13315	ATM	S141	L143P	143	Missense	proximal	2	no	9.840	10.629	EPSD	GDSC;CCLE	9.540	Up-regulation
Atypical_PIKK_ATM_ATM_ST	P78527	PRKDC	Q13315	ATM	S245	V252A	252	Missense	distal	7	no	10.698	10.681	EPSD	GDSC;CCLE	9.540	Down-regulation
Atypical_PIKK_ATM_ATM_ST	P78527	PRKDC	Q13315	ATM	S882	E889D	889	Missense	distal	7	no	9.878	9.890	EPSD	GDSC	9.540	Up-regulation
Atypical_PIKK_ATM_ATM_ST	P78527	PRKDC	Q13315	ATM	T946	M939V	939	Missense	distal	-7	no	10.518	10.512	EPSD	GDSC;CCLE	9.540	Down-regulation
Atypical_PIKK_ATM_ATM_ST	P78527	PRKDC	Q13315	ATM	S1162	S1162L	1162	Missense	central	0	yes	9.795	0.000	EPSD	GDSC;CCLE	9.540	Loss
Atypical_PIKK_ATM_ATM_ST	P78527	PRKDC	Q13315	ATM	S1162	R1155*	1155	Missense	distal	-7	no	9.795	9.084	EPSD	GDSC	9.540	Loss
Atypical_PIKK_ATM_ATM_ST	P78527	PRKDC	Q13315	ATM	S1162	L1168P	1168	Missense	distal	6	no	9.795	9.841	EPSD	GDSC;CCLE	9.540	Up-regulation
Atypical_PIKK_ATM_ATM_ST	P78527	PRKDC	Q13315	ATM	S1470	H1476Y	1476	Missense	distal	6	no	14.767	14.759	EPSD	GDSC;CCLE	9.540	Down-regulation
Atypical_PIKK_ATM_ATM_ST	Q99801	NKX3-1	Q13315	ATM	S48	S48R	48	Missense	central	0	yes	12.696	0.000	EPSD	GDSC;CCLE	9.540	Loss
Atypical_PIKK_ATM_ATM_ST	Q99801	NKX3-1	Q13315	ATM	S48	P54T	54	Missense	distal	6	no	12.696	12.697	EPSD	GDSC;CCLE	9.540	Up-regulation
Atypical_PIKK_ATM_ATM_ST	Q99801	NKX3-1	Q13315	ATM	T166	V168M	168	Missense	proximal	2	no	14.014	13.849	PhosphoSitePlus;EPSD	GDSC	9.540	Down-regulation
Atypical_PIKK_ATM_ATM_ST	Q99801	NKX3-1	Q13315	ATM	T166	W171C	171	Missense	distal	5	no	14.014	14.051	PhosphoSitePlus;EPSD	GDSC;CCLE	9.540	Up-regulation
Atypical_PIKK_ATM_ATM_ST	Q12888	TP53BP1	Q13315	ATM	S29	E33A	33	Missense	distal	4	no	14.774	14.725	PhosphoSitePlus;EPSD	GDSC	9.540	Down-regulation
Atypical_PIKK_ATM_ATM_ST	P08047	SP1	Q13315	ATM	S73	A66G	66	Missense	distal	-7	no	11.367	10.951	EPSD	GDSC;CCLE	9.540	Down-regulation
Atypical_PIKK_ATM_ATM_ST	P08047	SP1	Q13315	ATM	S617	S617L	617	Missense	central	0	yes	9.931	0.000	EPSD	GDSC	9.540	Loss
Atypical_PIKK_ATM_ATM_ST	P08047	SP1	Q13315	ATM	T739	T737A	737	Missense	proximal	-2	no	9.655	9.555	EPSD	GDSC	9.540	Down-regulation
Atypical_PIKK_ATM_ATM_ST	P08047	SP1	Q13315	ATM	T739	G736V	736	Missense	distal	-3	no	9.655	9.795	EPSD	GDSC;CCLE	9.540	Up-regulation
Atypical_PIKK_ATM_ATM_ST	P08047	SP1	Q13315	ATM	T739	A738T	738	Missense	proximal	-1	no	9.655	9.825	EPSD	GDSC;CCLE	9.540	Up-regulation
Atypical_PIKK_ATM_ATM_ST	O95071	UBR5	Q13315	ATM	S117	W112*	112	Missense	distal	-5	no	9.782	10.076	EPSD	GDSC	9.540	Up-regulation
Atypical_PIKK_ATM_ATM_ST	O95071	UBR5	Q13315	ATM	S1308	R1304*	1304	Missense	distal	-4	no	11.601	10.548	EPSD	GDSC	9.540	Down-regulation
Atypical_PIKK_ATM_ATM_ST	O95071	UBR5	Q13315	ATM	S1347	Q1348H	1348	Missense	proximal	1	no	13.700	-1.209	EPSD	GDSC;CCLE	9.540	Loss
Atypical_PIKK_ATM_ATM_ST	O95071	UBR5	Q13315	ATM	S1532	Q1533*	1533	Missense	proximal	1	no	15.306	3.782	EPSD;PhosphoSitePlus	GDSC	9.540	Loss
Atypical_PIKK_ATM_ATM_ST	O95071	UBR5	Q13315	ATM	S1549	P1543L	1543	Missense	distal	-6	no	16.098	15.869	EPSD	GDSC	9.540	Down-regulation
Atypical_PIKK_ATM_ATM_ST	O95071	UBR5	Q13315	ATM	S1679	Q1680*	1680	Missense	proximal	1	no	16.287	4.763	EPSD;PhosphoSitePlus	GDSC	9.540	Loss
Atypical_PIKK_ATM_ATM_ST	O95071	UBR5	Q13315	ATM	S1875	A1874T	1874	Missense	proximal	-1	no	12.796	12.967	EPSD	GDSC	9.540	Up-regulation
Atypical_PIKK_ATM_ATM_ST	O95071	UBR5	Q13315	ATM	S2241	Q2236L	2236	Missense	distal	-5	no	11.674	11.830	EPSD	GDSC	9.540	Up-regulation
Atypical_PIKK_ATM_ATM_ST	O95071	UBR5	Q13315	ATM	S2384	L2390S	2390	Missense	distal	6	no	11.328	11.384	EPSD	GDSC;CCLE	9.540	Up-regulation
Atypical_PIKK_ATM_ATM_ST	Q92945	KHSRP	Q13315	ATM	S274	D272N	272	Missense	proximal	-2	no	14.251	14.370	EPSD;PhosphoSitePlus	GDSC;CCLE	9.540	Up-regulation
Atypical_PIKK_ATM_ATM_ST	Q92945	KHSRP	Q13315	ATM	S480	I476T	476	Missense	distal	-4	no	9.489	9.818	EPSD	GDSC;CCLE	9.540	Gain
Atypical_PIKK_ATM_ATM_ST	Q92945	KHSRP	Q13315	ATM	S670	P664L	664	Missense	distal	-6	no	15.038	14.809	PhosphoSitePlus;EPSD	GDSC;CCLE	9.540	Down-regulation
Atypical_PIKK_ATM_ATM_ST	Q92945	KHSRP	Q13315	ATM	S670	P664S	664	Missense	distal	-6	no	15.038	15.097	PhosphoSitePlus;EPSD	GDSC;CCLE	9.540	Up-regulation
Atypical_PIKK_ATM_ATM_ST	Q96S59	RANBP9	Q13315	ATM	S487	S489G	489	Missense	proximal	2	no	11.402	10.543	EPSD	GDSC;CCLE	9.540	Down-regulation
Atypical_PIKK_ATM_ATM_ST	Q96S59	RANBP9	Q13315	ATM	S603	R607H	607	Missense	distal	4	no	17.357	17.292	PhosphoSitePlus;EPSD	GDSC;CCLE	9.540	Down-regulation
Atypical_PIKK_ATM_ATM_ST	Q96S59	RANBP9	Q13315	ATM	S603	E599*	599	Missense	distal	-4	no	17.357	15.214	PhosphoSitePlus;EPSD	GDSC	9.540	Down-regulation
Atypical_PIKK_ATM_ATM_ST	Q96S59	RANBP9	Q13315	ATM	S613	R607H	607	Missense	distal	-6	no	12.326	12.327	EPSD	GDSC;CCLE	9.540	Up-regulation
Atypical_PIKK_ATM_ATM_ST	Q92547	TOPBP1	Q13315	ATM	S301	N295S	295	Missense	distal	-6	no	16.182	16.298	EPSD	GDSC;CCLE	9.540	Up-regulation
Atypical_PIKK_ATM_ATM_ST	Q92547	TOPBP1	Q13315	ATM	S301	P299R	299	Missense	proximal	-2	no	16.182	15.976	EPSD	GDSC;CCLE	9.540	Down-regulation
Atypical_PIKK_ATM_ATM_ST	Q92547	TOPBP1	Q13315	ATM	S1159	N1160D	1160	Missense	proximal	1	no	6.961	10.792	EPSD	GDSC;CCLE	9.540	Gain
Atypical_PIKK_ATM_ATM_ST	Q92547	TOPBP1	Q13315	ATM	S1504	T1501N	1501	Missense	distal	-3	no	14.251	14.292	EPSD	GDSC;CCLE	9.540	Up-regulation
Atypical_PIKK_ATM_ATM_ST	P12956	XRCC6	Q13315	ATM	S319	L312V	312	Missense	distal	-7	no	12.037	12.144	EPSD	GDSC;CCLE	9.540	Up-regulation
Atypical_PIKK_ATM_ATM_ST	P12956	XRCC6	Q13315	ATM	T334	I327V	327	Missense	distal	-7	no	9.965	10.149	EPSD	GDSC;CCLE	9.540	Up-regulation
Atypical_PIKK_ATM_ATM_ST	Q96SD1	DCLRE1C	Q13315	ATM	S548	Q546E	546	Missense	proximal	-2	no	12.812	13.117	EPSD	GDSC	9.540	Up-regulation
Atypical_PIKK_ATM_ATM_ST	Q96SD1	DCLRE1C	Q13315	ATM	S553	Q546E	546	Missense	distal	-7	no	16.420	16.974	EPSD	GDSC	9.540	Up-regulation
Atypical_PIKK_ATM_ATM_ST	Q96SD1	DCLRE1C	Q13315	ATM	T656	P657L	657	Missense	proximal	1	no	9.967	8.412	EPSD;PhosphoSitePlus	GDSC;CCLE	9.540	Loss
Atypical_PIKK_ATM_ATM_ST	Q7LG56	RRM2B	Q13315	ATM	S25	E32Q	32	Missense	distal	7	no	10.055	10.069	EPSD	GDSC	9.540	Up-regulation
Atypical_PIKK_ATM_ATM_ST	Q9H2K8	TAOK3	Q13315	ATM	S359	V355M	355	Missense	distal	-4	no	15.904	15.885	PhosphoSitePlus;EPSD	GDSC	9.540	Down-regulation
Atypical_PIKK_ATM_ATM_ST	Q9H2K8	TAOK3	Q13315	ATM	T419	Q425R	425	Missense	distal	6	no	14.813	14.818	EPSD	GDSC;CCLE	9.540	Up-regulation
Atypical_PIKK_ATM_ATM_ST	Q9H2K8	TAOK3	Q13315	ATM	S424	Q425R	425	Missense	proximal	1	no	13.670	7.018	EPSD	GDSC;CCLE	9.540	Loss
Atypical_PIKK_ATM_ATM_ST	Q96RU2	USP28	Q13315	ATM	S67	E65*	65	Missense	proximal	-2	no	13.532	12.430	EPSD;PhosphoSitePlus	GDSC	9.540	Down-regulation
Atypical_PIKK_ATM_ATM_ST	Q96RU2	USP28	Q13315	ATM	S249	Q253*	253	Missense	distal	4	no	9.238	9.999	EPSD	GDSC	9.540	Gain
Atypical_PIKK_ATM_ATM_ST	Q96RU2	USP28	Q13315	ATM	S375	S375F	375	Missense	central	0	yes	11.657	0.000	EPSD	GDSC;CCLE	9.540	Loss
Atypical_PIKK_ATM_ATM_ST	Q96RU2	USP28	Q13315	ATM	S375	E380*	380	Missense	distal	5	no	11.657	12.313	EPSD	GDSC	9.540	Up-regulation
Atypical_PIKK_ATM_ATM_ST	Q96RU2	USP28	Q13315	ATM	S518	R519Q	519	Missense	proximal	1	no	7.127	13.778	EPSD	GDSC;CCLE	9.540	Gain
Atypical_PIKK_ATM_ATM_ST	Q96RU2	USP28	Q13315	ATM	S794	R791Q	791	Missense	distal	-3	no	10.360	9.585	EPSD	GDSC;CCLE	9.540	Down-regulation
Atypical_PIKK_ATM_ATM_ST	Q96RU2	USP28	Q13315	ATM	S856	A851S	851	Missense	distal	-5	no	11.522	11.529	EPSD	GDSC;CCLE	9.540	Up-regulation
Atypical_PIKK_ATM_ATM_ST	Q96RU2	USP28	Q13315	ATM	S856	R860G	860	Missense	distal	4	no	11.522	11.469	EPSD	GDSC	9.540	Down-regulation
Atypical_PIKK_ATM_ATM_ST	Q96RU2	USP28	Q13315	ATM	S856	N854D	854	Missense	proximal	-2	no	11.522	11.403	EPSD	GDSC;CCLE	9.540	Down-regulation
Atypical_PIKK_ATM_ATM_ST	Q5TZA2	CROCC	Q13315	ATM	S494	G489R	489	Missense	distal	-5	no	10.426	10.447	EPSD	GDSC	9.540	Up-regulation
Atypical_PIKK_ATM_ATM_ST	Q5TZA2	CROCC	Q13315	ATM	S494	L487R	487	Missense	distal	-7	no	10.426	10.615	EPSD	GDSC;CCLE	9.540	Up-regulation
Atypical_PIKK_ATM_ATM_ST	Q5TZA2	CROCC	Q13315	ATM	S506	G502D	502	Missense	distal	-4	no	10.429	11.213	EPSD	GDSC	9.540	Up-regulation
Atypical_PIKK_ATM_ATM_ST	Q5TZA2	CROCC	Q13315	ATM	S1499	T1495P	1495	Missense	distal	-4	no	10.289	10.003	EPSD	GDSC;CCLE	9.540	Down-regulation
Atypical_PIKK_ATM_ATM_ST	Q9BXW9	FANCD2	Q13315	ATM	S319	S319F	319	Missense	central	0	yes	12.400	0.000	EPSD	GDSC	9.540	Loss
Atypical_PIKK_ATM_ATM_ST	Q9BXW9	FANCD2	Q13315	ATM	S592	P593S	593	Missense	proximal	1	no	10.502	3.527	EPSD	GDSC	9.540	Loss
Atypical_PIKK_ATM_ATM_ST	Q9BXW9	FANCD2	Q13315	ATM	T596	P593S	593	Missense	distal	-3	no	13.484	13.287	EPSD	GDSC	9.540	Down-regulation
Atypical_PIKK_ATM_ATM_ST	Q9BXW9	FANCD2	Q13315	ATM	T596	L602V	602	Missense	distal	6	no	13.484	13.516	EPSD	GDSC;CCLE	9.540	Up-regulation
Atypical_PIKK_ATM_ATM_ST	Q9BXW9	FANCD2	Q13315	ATM	T608	L614*	614	Missense	distal	6	no	12.982	12.927	EPSD	GDSC	9.540	Down-regulation
Atypical_PIKK_ATM_ATM_ST	Q9BXW9	FANCD2	Q13315	ATM	T608	S612P	612	Missense	distal	4	no	12.982	13.105	EPSD	GDSC	9.540	Up-regulation
Atypical_PIKK_ATM_ATM_ST	Q9BXW9	FANCD2	Q13315	ATM	T608	L602V	602	Missense	distal	-6	no	12.982	13.014	EPSD	GDSC;CCLE	9.540	Up-regulation
Atypical_PIKK_ATM_ATM_ST	Q9BXW9	FANCD2	Q13315	ATM	S1404	D1410Y	1410	Missense	distal	6	no	16.008	15.989	EPSD	GDSC;CCLE	9.540	Down-regulation
Atypical_PIKK_ATM_ATM_ST	Q9BXW9	FANCD2	Q13315	ATM	S1412	Q1419K	1419	Missense	distal	7	no	10.826	10.839	EPSD	GDSC;CCLE	9.540	Up-regulation
Atypical_PIKK_ATM_ATM_ST	Q9BXW9	FANCD2	Q13315	ATM	S1412	D1410Y	1410	Missense	proximal	-2	no	10.826	10.955	EPSD	GDSC;CCLE	9.540	Up-regulation
Atypical_PIKK_ATM_ATM_ST	Q9BXW9	FANCD2	Q13315	ATM	S1418	Q1419K	1419	Missense	proximal	1	no	15.697	8.848	EPSD	GDSC;CCLE	9.540	Loss
Atypical_PIKK_ATM_ATM_ST	Q9BXW9	FANCD2	Q13315	ATM	S1446	S1443T	1443	Missense	distal	-3	no	12.229	12.161	EPSD	GDSC;CCLE	9.540	Down-regulation
Atypical_PIKK_ATM_ATM_ST	Q9BXW9	FANCD2	Q13315	ATM	S1450	S1443T	1443	Missense	distal	-7	no	9.570	9.489	EPSD	GDSC;CCLE	9.540	Loss
Atypical_PIKK_ATM_ATM_ST	Q969H0	FBXW7	Q13315	ATM	S10	K11Q	11	Missense	proximal	1	no	5.652	12.500	EPSD	GDSC;CCLE	9.540	Gain
Atypical_PIKK_ATM_ATM_ST	Q6PCD5	RFWD3	Q13315	ATM	S490	M487L	487	Missense	distal	-3	no	15.096	14.950	EPSD	GDSC;CCLE	9.540	Down-regulation
Atypical_PIKK_ATM_ATM_ST	Q6PCD5	RFWD3	Q13315	ATM	S490	M495L	495	Missense	distal	5	no	15.096	15.075	EPSD	GDSC;CCLE	9.540	Down-regulation
Atypical_PIKK_ATM_ATM_ST	Q6PCD5	RFWD3	Q13315	ATM	S490	M487R	487	Missense	distal	-3	no	15.096	15.481	EPSD	GDSC;CCLE	9.540	Up-regulation
Atypical_PIKK_ATM_ATM_ST	Q9UQR1	ZNF148	Q13315	ATM	S23	D18Y	18	Missense	distal	-5	no	10.657	10.891	EPSD	GDSC	9.540	Up-regulation
Atypical_PIKK_ATM_ATM_ST	Q9UQR1	ZNF148	Q13315	ATM	S23	T25A	25	Missense	proximal	2	no	10.657	10.336	EPSD	GDSC;CCLE	9.540	Down-regulation
Atypical_PIKK_ATM_ATM_ST	Q9UQR1	ZNF148	Q13315	ATM	S202	I209M	209	Missense	distal	7	no	12.906	12.908	PhosphoSitePlus	GDSC;CCLE	9.540	Up-regulation
Atypical_PIKK_ATM_ATM_ST	Q9UQR1	ZNF148	Q13315	ATM	S250	H245Y	245	Missense	distal	-5	no	9.873	9.848	EPSD	GDSC;CCLE	9.540	Down-regulation
Atypical_PIKK_ATM_ATM_ST	Q9UQR1	ZNF148	Q13315	ATM	S297	D300N	300	Missense	distal	3	no	10.670	10.687	EPSD	GDSC;CCLE	9.540	Up-regulation
Atypical_PIKK_ATM_ATM_ST	Q9UQR1	ZNF148	Q13315	ATM	S297	G292S	292	Missense	distal	-5	no	10.670	10.615	EPSD	GDSC;CCLE	9.540	Down-regulation
Atypical_PIKK_ATM_ATM_ST	Q9UQR1	ZNF148	Q13315	ATM	S297	D300V	300	Missense	distal	3	no	10.670	10.830	EPSD	GDSC;CCLE	9.540	Up-regulation
Atypical_PIKK_ATM_ATM_ST	Q9UQR1	ZNF148	Q13315	ATM	S306	D300N	300	Missense	distal	-6	no	9.859	9.770	EPSD	GDSC;CCLE	9.540	Down-regulation
Atypical_PIKK_ATM_ATM_ST	Q9UQR1	ZNF148	Q13315	ATM	S306	D300V	300	Missense	distal	-6	no	9.859	9.629	EPSD	GDSC;CCLE	9.540	Down-regulation
Atypical_PIKK_ATM_ATM_ST	Q9UQR1	ZNF148	Q13315	ATM	S625	N624S	624	Missense	proximal	-1	no	9.773	9.829	EPSD	GDSC	9.540	Up-regulation
Atypical_PIKK_ATM_ATM_ST	Q9UQR1	ZNF148	Q13315	ATM	S665	R660*	660	Missense	distal	-5	no	9.667	10.127	EPSD	GDSC	9.540	Up-regulation
Atypical_PIKK_ATM_ATM_ST	Q9UQR1	ZNF148	Q13315	ATM	S683	F689V	689	Missense	distal	6	no	12.936	12.988	EPSD	GDSC	9.540	Up-regulation
Atypical_PIKK_ATM_ATM_ST	Q96RL1	UIMC1	Q13315	ATM	S101	A96D	96	Missense	distal	-5	no	14.002	13.799	EPSD	GDSC;CCLE	9.540	Down-regulation
Atypical_PIKK_ATM_ATM_ST	Q96RL1	UIMC1	Q13315	ATM	S168	H169Q	169	Missense	proximal	1	no	-1.060	13.849	EPSD	GDSC;CCLE	9.540	Gain
Atypical_PIKK_ATM_ATM_ST	Q96RL1	UIMC1	Q13315	ATM	S171	H169Q	169	Missense	proximal	-2	no	10.004	10.307	EPSD	GDSC;CCLE	9.540	Up-regulation
Atypical_PIKK_ATM_ATM_ST	Q96RL1	UIMC1	Q13315	ATM	S171	I170V	170	Missense	proximal	-1	no	10.004	9.801	EPSD	GDSC;CCLE	9.540	Down-regulation
Atypical_PIKK_ATM_ATM_ST	Q96RL1	UIMC1	Q13315	ATM	S171	F165C	165	Missense	distal	-6	no	10.004	10.155	EPSD	GDSC;CCLE	9.540	Up-regulation
Atypical_PIKK_ATM_ATM_ST	Q96RL1	UIMC1	Q13315	ATM	S205	V212E	212	Missense	distal	7	no	14.539	14.487	PhosphoSitePlus	GDSC;CCLE	9.540	Down-regulation
Atypical_PIKK_ATM_ATM_ST	Q96RL1	UIMC1	Q13315	ATM	T228	G231E	231	Missense	distal	3	no	15.549	15.242	EPSD	GDSC;CCLE	9.540	Down-regulation
Atypical_PIKK_ATM_ATM_ST	Q96RL1	UIMC1	Q13315	ATM	S379	S380P	380	Missense	proximal	1	no	6.094	13.069	EPSD	GDSC	9.540	Gain
Atypical_PIKK_ATM_ATM_ST	Q96RL1	UIMC1	Q13315	ATM	S419	A418T	418	Missense	proximal	-1	no	16.206	16.376	EPSD	GDSC;CCLE	9.540	Up-regulation
Atypical_PIKK_ATM_ATM_ST	Q96RL1	UIMC1	Q13315	ATM	S644	S643F	643	Missense	proximal	-1	no	10.025	9.598	EPSD	GDSC;CCLE	9.540	Down-regulation
Atypical_PIKK_ATM_ATM_ST	Q96RL1	UIMC1	Q13315	ATM	T646	S643F	643	Missense	distal	-3	no	8.480	9.552	EPSD	GDSC;CCLE	9.540	Gain
Atypical_PIKK_ATM_ATM_ST	Q96T60	PNKP	Q13315	ATM	S114	R110H	110	Missense	distal	-4	no	15.948	16.078	EPSD;PhosphoSitePlus	GDSC;CCLE	9.540	Up-regulation
Atypical_PIKK_ATM_ATM_ST	Q96T60	PNKP	Q13315	ATM	S114	R110C	110	Missense	distal	-4	no	15.948	15.185	EPSD;PhosphoSitePlus	GDSC;CCLE	9.540	Down-regulation
Atypical_PIKK_ATM_ATM_ST	Q01094	E2F1	Q13315	ATM	S307	G309E	309	Missense	proximal	2	no	9.855	11.224	EPSD	GDSC;CCLE	9.540	Up-regulation
Atypical_PIKK_ATM_ATM_ST	Q01094	E2F1	Q13315	ATM	S313	G309E	309	Missense	distal	-4	no	13.870	14.936	EPSD	GDSC;CCLE	9.540	Up-regulation
Atypical_PIKK_ATM_ATM_ST	Q01094	E2F1	Q13315	ATM	S318	R323K	323	Missense	distal	5	no	9.741	9.579	EPSD	GDSC	9.540	Down-regulation
Atypical_PIKK_ATM_ATM_ST	Q01094	E2F1	Q13315	ATM	S318	A324T	324	Missense	distal	6	no	9.741	9.724	EPSD	GDSC	9.540	Down-regulation
Atypical_PIKK_ATM_ATM_ST	Q01094	E2F1	Q13315	ATM	S347	L351V	351	Missense	distal	4	no	14.776	14.740	EPSD	GDSC;CCLE	9.540	Down-regulation
Atypical_PIKK_ATM_ATM_ST	Q01094	E2F1	Q13315	ATM	S347	S349Y	349	Missense	proximal	2	no	14.776	13.915	EPSD	GDSC;CCLE	9.540	Down-regulation
Atypical_PIKK_ATM_ATM_ST	O96017	CHEK2	Q13315	ATM	T68	S73F	73	Missense	distal	5	no	14.453	14.759	EPSD;PhosphoSitePlus	GDSC;CCLE	9.540	Up-regulation
Atypical_PIKK_ATM_ATM_ST	Q8IY92	SLX4	Q13315	ATM	S173	E179D	179	Missense	distal	6	no	9.696	9.649	EPSD	GDSC	9.540	Down-regulation
Atypical_PIKK_ATM_ATM_ST	Q8IY92	SLX4	Q13315	ATM	S186	P182A	182	Missense	distal	-4	no	14.902	15.061	EPSD	GDSC;CCLE	9.540	Up-regulation
Atypical_PIKK_ATM_ATM_ST	Q8IY92	SLX4	Q13315	ATM	S186	E179D	179	Missense	distal	-7	no	14.902	14.324	EPSD	GDSC	9.540	Down-regulation
Atypical_PIKK_ATM_ATM_ST	Q8IY92	SLX4	Q13315	ATM	S383	P378A	378	Missense	distal	-5	no	12.279	12.267	EPSD	GDSC;CCLE	9.540	Down-regulation
Atypical_PIKK_ATM_ATM_ST	Q8IY92	SLX4	Q13315	ATM	S492	E493G	493	Missense	proximal	1	no	10.635	10.058	EPSD	GDSC;CCLE	9.540	Down-regulation
Atypical_PIKK_ATM_ATM_ST	Q8IY92	SLX4	Q13315	ATM	S492	E493K	493	Missense	proximal	1	no	10.635	9.683	EPSD	GDSC;CCLE	9.540	Down-regulation
Atypical_PIKK_ATM_ATM_ST	Q8IY92	SLX4	Q13315	ATM	T500	E493G	493	Missense	distal	-7	no	11.655	10.787	EPSD	GDSC;CCLE	9.540	Down-regulation
Atypical_PIKK_ATM_ATM_ST	Q8IY92	SLX4	Q13315	ATM	T500	E493K	493	Missense	distal	-7	no	11.655	10.987	EPSD	GDSC;CCLE	9.540	Down-regulation
Atypical_PIKK_ATM_ATM_ST	Q8IY92	SLX4	Q13315	ATM	S659	P664T	664	Missense	distal	5	no	14.326	14.128	EPSD	GDSC;CCLE	9.540	Down-regulation
Atypical_PIKK_ATM_ATM_ST	Q8IY92	SLX4	Q13315	ATM	S659	D665N	665	Missense	distal	6	no	14.326	14.338	EPSD	GDSC;CCLE	9.540	Up-regulation
Atypical_PIKK_ATM_ATM_ST	Q8IY92	SLX4	Q13315	ATM	S884	W879*	879	Missense	distal	-5	no	11.524	11.818	EPSD	GDSC	9.540	Up-regulation
Atypical_PIKK_ATM_ATM_ST	Q8IY92	SLX4	Q13315	ATM	S960	L953F	953	Missense	distal	-7	no	10.071	9.829	EPSD	GDSC;CCLE	9.540	Down-regulation
Atypical_PIKK_ATM_ATM_ST	Q8IY92	SLX4	Q13315	ATM	S960	S960I	960	Missense	central	0	yes	10.071	0.000	EPSD	GDSC;CCLE	9.540	Loss
Atypical_PIKK_ATM_ATM_ST	Q8IY92	SLX4	Q13315	ATM	S1121	P1122S	1122	Missense	proximal	1	no	9.742	2.767	EPSD	GDSC;CCLE	9.540	Loss
Atypical_PIKK_ATM_ATM_ST	Q8IY92	SLX4	Q13315	ATM	T1127	P1131S	1131	Missense	distal	4	no	13.533	13.410	EPSD	GDSC;CCLE	9.540	Down-regulation
Atypical_PIKK_ATM_ATM_ST	Q8IY92	SLX4	Q13315	ATM	T1127	P1122S	1122	Missense	distal	-5	no	13.533	13.529	EPSD	GDSC;CCLE	9.540	Down-regulation
Atypical_PIKK_ATM_ATM_ST	Q8IY92	SLX4	Q13315	ATM	S1136	P1131S	1131	Missense	distal	-5	no	11.058	11.055	EPSD	GDSC;CCLE	9.540	Down-regulation
Atypical_PIKK_ATM_ATM_ST	Q8IY92	SLX4	Q13315	ATM	S1138	P1131S	1131	Missense	distal	-7	no	14.212	14.448	EPSD;PhosphoSitePlus	GDSC;CCLE	9.540	Up-regulation
Atypical_PIKK_ATM_ATM_ST	Q8IY92	SLX4	Q13315	ATM	S1185	E1178Q	1178	Missense	distal	-7	no	11.136	10.582	EPSD	GDSC;CCLE	9.540	Down-regulation
Atypical_PIKK_ATM_ATM_ST	Q8IY92	SLX4	Q13315	ATM	S1185	S1185N	1185	Missense	central	0	yes	11.136	0.000	EPSD	GDSC;CCLE	9.540	Loss
Atypical_PIKK_ATM_ATM_ST	Q8IY92	SLX4	Q13315	ATM	S1244	S1249N	1249	Missense	distal	5	no	9.560	9.535	EPSD	GDSC;CCLE	9.540	Loss
Atypical_PIKK_ATM_ATM_ST	Q8IY92	SLX4	Q13315	ATM	T1288	T1291M	1291	Missense	distal	3	no	12.351	12.527	EPSD	GDSC;CCLE	9.540	Up-regulation
Atypical_PIKK_ATM_ATM_ST	Q8IY92	SLX4	Q13315	ATM	S1716	S1718N	1718	Missense	proximal	2	no	14.699	14.058	EPSD;PhosphoSitePlus	GDSC	9.540	Down-regulation
Atypical_PIKK_ATM_ATM_ST	Q8IY92	SLX4	Q13315	ATM	S1716	S1715N	1715	Missense	proximal	-1	no	14.699	14.644	EPSD;PhosphoSitePlus	GDSC;CCLE	9.540	Down-regulation
Atypical_PIKK_ATM_ATM_ST	Q6UWZ7	ABRAXAS1	Q13315	ATM	T365	R369*	369	Missense	distal	4	no	10.332	10.945	EPSD	GDSC	9.540	Up-regulation
Atypical_PIKK_ATM_ATM_ST	Q6UWZ7	ABRAXAS1	Q13315	ATM	T365	D364E	364	Missense	proximal	-1	no	10.332	10.597	EPSD	GDSC	9.540	Up-regulation
Atypical_PIKK_ATM_ATM_ST	Q9UGP5	POLL	Q13315	ATM	S43	R45Q	45	Missense	proximal	2	no	9.226	9.922	EPSD	GDSC	9.540	Gain
Atypical_PIKK_ATM_ATM_ST	Q9UGP5	POLL	Q13315	ATM	T204	S199G	199	Missense	distal	-5	no	12.953	13.008	PhosphoSitePlus	GDSC	9.540	Up-regulation
Atypical_PIKK_ATM_ATM_ST	P60484	PTEN	Q13315	ATM	S113	L112R	112	Missense	proximal	-1	no	12.108	11.868	EPSD;PhosphoSitePlus	GDSC;CCLE	9.540	Down-regulation
Atypical_PIKK_ATM_ATM_ST	P60484	PTEN	Q13315	ATM	S113	D115Y	115	Missense	proximal	2	no	12.108	10.867	EPSD;PhosphoSitePlus	GDSC;CCLE	9.540	Down-regulation
Atypical_PIKK_ATM_ATM_ST	P60484	PTEN	Q13315	ATM	S170	Y177*	177	Missense	distal	7	no	12.740	12.796	EPSD	GDSC	9.540	Up-regulation
Atypical_PIKK_ATM_ATM_ST	P60484	PTEN	Q13315	ATM	S338	R335*	335	Missense	distal	-3	no	9.307	9.797	EPSD	GDSC	9.540	Gain
Atypical_PIKK_ATM_ATM_ST	P60484	PTEN	Q13315	ATM	T398	Q399*	399	Missense	proximal	1	no	15.262	3.737	PhosphoSitePlus;EPSD	GDSC	9.540	Loss
Atypical_PIKK_ATM_ATM_ST	P23025	XPA	Q13315	ATM	S173	V166A	166	Missense	distal	-7	no	13.775	14.159	EPSD;PhosphoSitePlus	GDSC	9.540	Up-regulation
Atypical_PIKK_ATM_ATM_ST	P16220	CREB1	Q13315	ATM	S111	S111L	111	Missense	central	0	yes	15.623	0.000	EPSD;PhosphoSitePlus	GDSC;CCLE	9.540	Loss
Atypical_PIKK_ATM_ATM_ST	P35637	FUS	Q13315	ATM	S84	T78P	78	Missense	distal	-6	no	16.268	16.279	EPSD	GDSC	9.540	Up-regulation
Atypical_PIKK_ATM_ATM_ST	P35637	FUS	Q13315	ATM	S131	P125H	125	Missense	distal	-6	no	14.789	14.669	EPSD	GDSC;CCLE	9.540	Down-regulation
Atypical_PIKK_ATM_ATM_ST	Q7Z6Z7	HUWE1	Q13315	ATM	S1218	P1212S	1212	Missense	distal	-6	no	10.342	10.402	EPSD	GDSC;CCLE	9.540	Up-regulation
Atypical_PIKK_ATM_ATM_ST	Q7Z6Z7	HUWE1	Q13315	ATM	S1370	D1373N	1373	Missense	distal	3	no	10.535	10.552	EPSD	GDSC;CCLE	9.540	Up-regulation
Atypical_PIKK_ATM_ATM_ST	Q7Z6Z7	HUWE1	Q13315	ATM	S1505	A1498S	1498	Missense	distal	-7	no	10.056	10.152	EPSD	GDSC;CCLE	9.540	Up-regulation
Atypical_PIKK_ATM_ATM_ST	Q7Z6Z7	HUWE1	Q13315	ATM	S2391	S2391G	2391	Missense	central	0	yes	13.767	0.000	EPSD	GDSC	9.540	Loss
Atypical_PIKK_ATM_ATM_ST	Q7Z6Z7	HUWE1	Q13315	ATM	S2636	T2633I	2633	Missense	distal	-3	no	14.756	15.493	EPSD;PhosphoSitePlus	GDSC;CCLE	9.540	Up-regulation
Atypical_PIKK_ATM_ATM_ST	Q7Z6Z7	HUWE1	Q13315	ATM	S2850	S2850C	2850	Missense	central	0	yes	12.588	0.000	EPSD	GDSC	9.540	Loss
Atypical_PIKK_ATM_ATM_ST	Q7Z6Z7	HUWE1	Q13315	ATM	S3797	A3792S	3792	Missense	distal	-5	no	14.874	14.882	PhosphoSitePlus;EPSD	GDSC	9.540	Up-regulation
Atypical_PIKK_ATM_ATM_ST	Q7Z6Z7	HUWE1	Q13315	ATM	S3799	A3792S	3792	Missense	distal	-7	no	10.218	10.314	EPSD	GDSC	9.540	Up-regulation
Atypical_PIKK_ATM_ATM_ST	Q15648	MED1	Q13315	ATM	S719	P722H	722	Missense	distal	3	no	14.366	14.437	EPSD	GDSC;CCLE	9.540	Up-regulation
Atypical_PIKK_ATM_ATM_ST	Q15648	MED1	Q13315	ATM	S772	D778N	778	Missense	distal	6	no	9.612	9.624	EPSD	GDSC;CCLE	9.540	Up-regulation
Atypical_PIKK_ATM_ATM_ST	Q15648	MED1	Q13315	ATM	S848	A845T	845	Missense	distal	-3	no	11.270	11.647	EPSD	GDSC;CCLE	9.540	Up-regulation
Atypical_PIKK_ATM_ATM_ST	Q15648	MED1	Q13315	ATM	S848	S851G	851	Missense	distal	3	no	11.270	11.400	EPSD	GDSC;CCLE	9.540	Up-regulation
Atypical_PIKK_ATM_ATM_ST	Q15648	MED1	Q13315	ATM	S850	S851G	851	Missense	proximal	1	no	4.815	10.119	EPSD	GDSC;CCLE	9.540	Gain
Atypical_PIKK_ATM_ATM_ST	Q15648	MED1	Q13315	ATM	S851	N856D	856	Missense	distal	5	no	9.486	9.598	EPSD	GDSC;CCLE	9.540	Gain
Atypical_PIKK_ATM_ATM_ST	Q15648	MED1	Q13315	ATM	S853	N856D	856	Missense	distal	3	no	9.690	9.673	EPSD	GDSC;CCLE	9.540	Down-regulation
Atypical_PIKK_ATM_ATM_ST	Q15648	MED1	Q13315	ATM	S853	S851G	851	Missense	proximal	-2	no	9.690	9.248	EPSD	GDSC;CCLE	9.540	Loss
Atypical_PIKK_ATM_ATM_ST	Q15648	MED1	Q13315	ATM	S900	T905I	905	Missense	distal	5	no	12.661	12.887	EPSD	GDSC;CCLE	9.540	Up-regulation
Atypical_PIKK_ATM_ATM_ST	Q15648	MED1	Q13315	ATM	S953	M947T	947	Missense	distal	-6	no	13.399	13.575	EPSD;PhosphoSitePlus	GDSC;CCLE	9.540	Up-regulation
Atypical_PIKK_ATM_ATM_ST	Q15648	MED1	Q13315	ATM	S1196	G1201V	1201	Missense	distal	5	no	9.858	9.892	EPSD	GDSC;CCLE	9.540	Up-regulation
Atypical_PIKK_ATM_ATM_ST	Q15648	MED1	Q13315	ATM	S1223	I1225F	1225	Missense	proximal	2	no	9.627	8.834	EPSD	GDSC;CCLE	9.540	Loss
Atypical_PIKK_ATM_ATM_ST	Q15648	MED1	Q13315	ATM	S1536	D1541E	1541	Missense	distal	5	no	10.601	10.343	EPSD	GDSC;CCLE	9.540	Down-regulation
Atypical_PIKK_ATM_ATM_ST	Q15648	MED1	Q13315	ATM	S1540	D1541E	1541	Missense	proximal	1	no	9.538	9.672	EPSD	GDSC;CCLE	9.540	Gain
Atypical_PIKK_ATM_ATM_ST	Q9BQ15	NABP2	Q13315	ATM	S182	R178Q	178	Missense	distal	-4	no	12.866	13.231	EPSD	GDSC;CCLE	9.540	Up-regulation
Atypical_PIKK_ATM_ATM_ST	Q9BQ15	NABP2	Q13315	ATM	S182	P175A	175	Missense	distal	-7	no	12.866	13.005	EPSD	GDSC;CCLE	9.540	Up-regulation
Atypical_PIKK_ATM_ATM_ST	P46527	CDKN1B	Q13315	ATM	S140	E146Q	146	Missense	distal	6	no	16.385	16.338	PhosphoSitePlus	GDSC;CCLE	9.540	Down-regulation
Atypical_PIKK_ATM_ATM_ST	P46527	CDKN1B	Q13315	ATM	S140	P137L	137	Missense	distal	-3	no	16.385	16.397	PhosphoSitePlus	GDSC;CCLE	9.540	Up-regulation
Atypical_PIKK_ATM_ATM_ST	P38398	BRCA1	Q13315	ATM	S896	Q895*	895	Missense	proximal	-1	no	9.789	9.125	EPSD	GDSC	9.540	Loss
Atypical_PIKK_ATM_ATM_ST	P38398	BRCA1	Q13315	ATM	S956	L954I	954	Missense	proximal	-2	no	13.238	12.938	EPSD	GDSC;CCLE	9.540	Down-regulation
Atypical_PIKK_ATM_ATM_ST	P38398	BRCA1	Q13315	ATM	S956	G949C	949	Missense	distal	-7	no	13.238	13.077	EPSD	GDSC;CCLE	9.540	Down-regulation
Atypical_PIKK_ATM_ATM_ST	P38398	BRCA1	Q13315	ATM	S1239	K1233I	1233	Missense	distal	-6	no	11.480	11.193	EPSD	GDSC;CCLE	9.540	Down-regulation
Atypical_PIKK_ATM_ATM_ST	P38398	BRCA1	Q13315	ATM	S1239	N1236K	1236	Missense	distal	-3	no	11.480	11.415	EPSD	GDSC	9.540	Down-regulation
Atypical_PIKK_ATM_ATM_ST	P38398	BRCA1	Q13315	ATM	T1394	D1398N	1398	Missense	distal	4	no	13.113	13.032	EPSD	GDSC;CCLE	9.540	Down-regulation
Atypical_PIKK_ATM_ATM_ST	P38398	BRCA1	Q13315	ATM	S1457	A1453S	1453	Missense	distal	-4	no	14.423	14.933	PhosphoSitePlus;EPSD	GDSC	9.540	Up-regulation
Atypical_PIKK_ATM_ATM_ST	P38398	BRCA1	Q13315	ATM	S1486	A1481V	1481	Missense	distal	-5	no	10.008	10.129	EPSD	GDSC;CCLE	9.540	Up-regulation
Atypical_PIKK_ATM_ATM_ST	P38398	BRCA1	Q13315	ATM	S1524	Q1518H	1518	Missense	distal	-6	no	14.600	14.458	EPSD;PhosphoSitePlus	GDSC	9.540	Down-regulation
Atypical_PIKK_ATM_ATM_ST	P38398	BRCA1	Q13315	ATM	S1542	S1542C	1542	Missense	central	0	yes	12.092	0.000	EPSD;PhosphoSitePlus	GDSC	9.540	Loss
Atypical_PIKK_ATM_ATM_ST	Q8NHY2	COP1	Q13315	ATM	S387	F392L	392	Missense	distal	5	no	14.681	14.539	PhosphoSitePlus	GDSC	9.540	Down-regulation
Atypical_PIKK_ATM_ATM_ST	Q99708	RBBP8	Q13315	ATM	S568	P569S	569	Missense	proximal	1	no	11.175	4.199	EPSD	GDSC;CCLE	9.540	Loss
Atypical_PIKK_ATM_ATM_ST	Q99708	RBBP8	Q13315	ATM	T596	E597Q	597	Missense	proximal	1	no	9.183	15.080	EPSD	GDSC;CCLE	9.540	Gain
Atypical_PIKK_ATM_ATM_ST	Q99708	RBBP8	Q13315	ATM	S664	I657V	657	Missense	distal	-7	no	13.382	13.566	EPSD;PhosphoSitePlus	GDSC;CCLE	9.540	Up-regulation
Atypical_PIKK_ATM_ATM_ST	Q99708	RBBP8	Q13315	ATM	S679	K676N	676	Missense	distal	-3	no	13.734	13.799	EPSD	GDSC	9.540	Up-regulation
Atypical_PIKK_ATM_ATM_ST	Q99708	RBBP8	Q13315	ATM	S679	S679G	679	Missense	central	0	yes	13.734	0.000	EPSD	GDSC;CCLE	9.540	Loss
Atypical_PIKK_ATM_ATM_ST	Q99708	RBBP8	Q13315	ATM	S723	M727T	727	Missense	distal	4	no	10.530	10.357	EPSD	GDSC;CCLE	9.540	Down-regulation
Atypical_PIKK_ATM_ATM_ST	Q99708	RBBP8	Q13315	ATM	S745	A741V	741	Missense	distal	-4	no	14.380	13.900	PhosphoSitePlus;EPSD	GDSC;CCLE	9.540	Down-regulation
Atypical_PIKK_ATM_ATM_ST	Q99708	RBBP8	Q13315	ATM	S789	G783C	783	Missense	distal	-6	no	9.823	9.645	EPSD	GDSC;CCLE	9.540	Down-regulation
Atypical_PIKK_ATM_ATM_ST	O75150	RNF40	Q13315	ATM	S114	S119C	119	Missense	distal	5	no	14.381	14.607	EPSD;PhosphoSitePlus	GDSC;CCLE	9.540	Up-regulation
Atypical_PIKK_ATM_ATM_ST	O75150	RNF40	Q13315	ATM	S219	D218N	218	Missense	proximal	-1	no	10.983	10.982	EPSD	GDSC	9.540	Down-regulation
Atypical_PIKK_ATM_ATM_ST	Q5VTR2	RNF20	Q13315	ATM	S28	E33*	33	Missense	distal	5	no	9.751	10.407	EPSD	GDSC	9.540	Up-regulation
Atypical_PIKK_ATM_ATM_ST	Q5VTR2	RNF20	Q13315	ATM	T85	A84T	84	Missense	proximal	-1	no	10.867	11.038	EPSD	GDSC;CCLE	9.540	Up-regulation
Atypical_PIKK_ATM_ATM_ST	Q5VTR2	RNF20	Q13315	ATM	S262	R263*	263	Missense	proximal	1	no	10.393	5.520	EPSD	GDSC	9.540	Loss
Atypical_PIKK_ATM_ATM_ST	Q5VTR2	RNF20	Q13315	ATM	S540	S544P	544	Missense	distal	4	no	9.612	9.735	EPSD	GDSC;CCLE	9.540	Up-regulation
Atypical_PIKK_ATM_ATM_ST	Q5VTR2	RNF20	Q13315	ATM	S545	S544P	544	Missense	proximal	-1	no	16.618	16.326	PhosphoSitePlus;EPSD	GDSC;CCLE	9.540	Down-regulation
Atypical_PIKK_ATM_ATM_ST	O15355	PPM1G	Q13315	ATM	S183	N187S	187	Missense	distal	4	no	14.208	14.081	PhosphoSitePlus	GDSC;CCLE	9.540	Down-regulation
Atypical_PIKK_ATM_ATM_ST	O15355	PPM1G	Q13315	ATM	S325	G324V	324	Missense	proximal	-1	no	9.571	9.339	EPSD	GDSC;CCLE	9.540	Loss
Atypical_PIKK_ATM_ATM_ST	Q14839	CHD4	Q13315	ATM	T46	L43*	43	Missense	distal	-3	no	8.922	9.943	EPSD	GDSC	9.540	Gain
Atypical_PIKK_ATM_ATM_ST	Q14839	CHD4	Q13315	ATM	T46	L43F	43	Missense	distal	-3	no	8.922	9.784	EPSD	GDSC;CCLE	9.540	Gain
Atypical_PIKK_ATM_ATM_ST	Q14839	CHD4	Q13315	ATM	T48	L43*	43	Missense	distal	-5	no	9.201	9.714	EPSD	GDSC	9.540	Gain
Atypical_PIKK_ATM_ATM_ST	Q14839	CHD4	Q13315	ATM	T529	N528D	528	Missense	proximal	-1	no	9.715	9.716	EPSD	GDSC;CCLE	9.540	Up-regulation
Atypical_PIKK_ATM_ATM_ST	Q14839	CHD4	Q13315	ATM	S531	N528D	528	Missense	distal	-3	no	9.411	9.684	EPSD	GDSC;CCLE	9.540	Gain
Atypical_PIKK_ATM_ATM_ST	Q14839	CHD4	Q13315	ATM	S1531	K1529M	1529	Missense	proximal	-2	no	13.042	12.999	EPSD	GDSC;CCLE	9.540	Down-regulation
Atypical_PIKK_ATM_ATM_ST	Q14839	CHD4	Q13315	ATM	S1535	P1541H	1541	Missense	distal	6	no	10.548	10.525	EPSD	GDSC;CCLE	9.540	Down-regulation
Atypical_PIKK_ATM_ATM_ST	Q14839	CHD4	Q13315	ATM	S1535	K1529M	1529	Missense	distal	-6	no	10.548	10.416	EPSD	GDSC;CCLE	9.540	Down-regulation
Atypical_PIKK_ATM_ATM_ST	Q14839	CHD4	Q13315	ATM	T1595	P1598T	1598	Missense	distal	3	no	12.304	12.232	EPSD	GDSC;CCLE	9.540	Down-regulation
Atypical_PIKK_ATM_ATM_ST	Q14839	CHD4	Q13315	ATM	S1602	P1598T	1598	Missense	distal	-4	no	9.270	9.556	EPSD	GDSC;CCLE	9.540	Gain
Atypical_PIKK_ATM_ATM_ST	Q14839	CHD4	Q13315	ATM	T1904	A1900T	1900	Missense	distal	-4	no	9.590	9.717	EPSD	GDSC;CCLE	9.540	Up-regulation
Atypical_PIKK_ATM_ATM_ST	Q9NQS1	AVEN	Q13315	ATM	S268	P262L	262	Missense	distal	-6	no	12.284	12.054	EPSD	GDSC;CCLE	9.540	Down-regulation
Atypical_PIKK_ATM_ATM_ST	Q9NQS1	AVEN	Q13315	ATM	S268	Q269H	269	Missense	proximal	1	no	12.284	-2.625	EPSD	GDSC;CCLE	9.540	Loss
Atypical_PIKK_ATM_ATM_ST	P49959	MRE11	Q13315	ATM	T481	R483L	483	Missense	proximal	2	no	13.419	13.173	EPSD	GDSC	9.540	Down-regulation
Atypical_PIKK_ATM_ATM_ST	P49959	MRE11	Q13315	ATM	S531	R525K	525	Missense	distal	-6	no	14.656	14.723	EPSD	GDSC	9.540	Up-regulation
Atypical_PIKK_ATM_ATM_ST	P49959	MRE11	Q13315	ATM	S563	A564T	564	Missense	proximal	1	no	10.164	7.228	EPSD	GDSC	9.540	Loss
Atypical_PIKK_ATM_ATM_ST	P49959	MRE11	Q13315	ATM	S590	G589E	589	Missense	proximal	-1	no	13.983	14.385	EPSD	GDSC	9.540	Up-regulation
Atypical_PIKK_ATM_ATM_ST	O00255	MEN1	Q13315	ATM	S399	R394K	394	Missense	distal	-5	no	16.788	16.629	EPSD	GDSC	9.540	Down-regulation
Atypical_PIKK_ATM_ATM_ST	Q8TAQ5	ZNF420	Q13315	ATM	S68	T65R	65	Missense	distal	-3	no	13.803	14.611	PhosphoSitePlus	GDSC;CCLE	9.540	Up-regulation
Atypical_PIKK_ATM_ATM_ST	Q9BXS6	NUSAP1	Q13315	ATM	T347	S352F	352	Missense	distal	5	no	13.787	14.093	EPSD	GDSC;CCLE	9.540	Up-regulation
Atypical_PIKK_ATM_ATM_ST	Q9BXS6	NUSAP1	Q13315	ATM	T349	S352F	352	Missense	distal	3	no	8.961	9.543	EPSD	GDSC;CCLE	9.540	Gain
Atypical_PIKK_ATM_ATM_ST	Q9BXS6	NUSAP1	Q13315	ATM	S363	V357A	357	Missense	distal	-6	no	10.150	10.386	EPSD	GDSC	9.540	Up-regulation
Atypical_PIKK_ATM_ATM_ST	Q9BXS6	NUSAP1	Q13315	ATM	S363	Y370C	370	Missense	distal	7	no	10.150	10.169	EPSD	GDSC;CCLE	9.540	Up-regulation
Atypical_PIKK_ATM_ATM_ST	Q9NS91	RAD18	Q13315	ATM	S146	E152*	152	Missense	distal	6	no	11.295	11.159	EPSD	GDSC	9.540	Down-regulation
Atypical_PIKK_ATM_ATM_ST	Q9NS91	RAD18	Q13315	ATM	S403	S409F	409	Missense	distal	6	no	13.694	13.618	PhosphoSitePlus	GDSC;CCLE	9.540	Down-regulation
Atypical_PIKK_ATM_ATM_ST	Q9NS91	RAD18	Q13315	ATM	S409	S409F	409	Missense	central	0	yes	10.073	0.000	EPSD	GDSC;CCLE	9.540	Loss
Atypical_PIKK_ATM_ATM_ST	Q9NS91	RAD18	Q13315	ATM	S471	R473I	473	Missense	proximal	2	no	10.322	10.635	EPSD	GDSC;CCLE	9.540	Up-regulation
Atypical_PIKK_ATM_ATM_ST	P15927	RPA2	Q13315	ATM	S72	E70K	70	Missense	proximal	-2	no	14.027	13.451	EPSD	GDSC;CCLE	9.540	Down-regulation
Atypical_PIKK_ATM_ATM_ST	Q9UBU7	DBF4	Q13315	ATM	T449	R445K	445	Missense	distal	-4	no	13.057	13.174	EPSD;PhosphoSitePlus	GDSC;CCLE	9.540	Up-regulation
Atypical_PIKK_ATM_ATM_ST	Q9UBU7	DBF4	Q13315	ATM	T449	I444V	444	Missense	distal	-5	no	13.057	13.055	EPSD;PhosphoSitePlus	GDSC;CCLE	9.540	Down-regulation
Atypical_PIKK_ATM_ATM_ST	Q9UBU7	DBF4	Q13315	ATM	S502	T497A	497	Missense	distal	-5	no	15.223	15.304	PhosphoSitePlus;EPSD	GDSC;CCLE	9.540	Up-regulation
Atypical_PIKK_ATM_ATM_ST	Q9UBU7	DBF4	Q13315	ATM	S665	A661V	661	Missense	distal	-4	no	9.848	9.368	EPSD	GDSC	9.540	Loss
Atypical_PIKK_ATM_ATM_ST	Q14247	CTTN	Q13315	ATM	S113	V115A	115	Missense	proximal	2	no	14.639	14.948	PhosphoSitePlus	GDSC;CCLE	9.540	Up-regulation
Atypical_PIKK_ATM_ATM_ST	Q9Y6D9	MAD1L1	Q13315	ATM	S185	R182G	182	Missense	distal	-3	no	9.557	9.096	EPSD	GDSC	9.540	Loss
Atypical_PIKK_ATM_ATM_ST	Q9Y6D9	MAD1L1	Q13315	ATM	S185	L183R	183	Missense	proximal	-2	no	9.557	9.504	EPSD	GDSC;CCLE	9.540	Loss
Atypical_PIKK_ATM_ATM_ST	Q9Y6D9	MAD1L1	Q13315	ATM	S494	T500M	500	Missense	distal	6	no	10.044	10.024	EPSD	GDSC	9.540	Down-regulation
Atypical_PIKK_ATM_ATM_ST	P15374	UCHL3	Q13315	ATM	S130	E125G	125	Missense	distal	-5	no	10.957	11.176	EPSD	GDSC;CCLE	9.540	Up-regulation
Atypical_PIKK_ATM_ATM_ST	Q70CQ2	USP34	Q13315	ATM	S143	S142I	142	Missense	proximal	-1	no	9.892	9.671	EPSD	GDSC;CCLE	9.540	Down-regulation
Atypical_PIKK_ATM_ATM_ST	Q70CQ2	USP34	Q13315	ATM	S649	L655M	655	Missense	distal	6	no	14.044	14.071	EPSD	GDSC;CCLE	9.540	Up-regulation
Atypical_PIKK_ATM_ATM_ST	Q70CQ2	USP34	Q13315	ATM	S649	L655R	655	Missense	distal	6	no	14.044	14.082	EPSD	GDSC	9.540	Up-regulation
Atypical_PIKK_ATM_ATM_ST	Q70CQ2	USP34	Q13315	ATM	S658	L655M	655	Missense	distal	-3	no	12.913	13.059	EPSD	GDSC;CCLE	9.540	Up-regulation
Atypical_PIKK_ATM_ATM_ST	Q70CQ2	USP34	Q13315	ATM	S658	M661L	661	Missense	distal	3	no	12.913	12.939	EPSD	GDSC;CCLE	9.540	Up-regulation
Atypical_PIKK_ATM_ATM_ST	Q70CQ2	USP34	Q13315	ATM	S658	L655R	655	Missense	distal	-3	no	12.913	13.444	EPSD	GDSC	9.540	Up-regulation
Atypical_PIKK_ATM_ATM_ST	Q70CQ2	USP34	Q13315	ATM	S718	C722F	722	Missense	distal	4	no	15.869	16.188	EPSD;PhosphoSitePlus	GDSC	9.540	Up-regulation
Atypical_PIKK_ATM_ATM_ST	Q70CQ2	USP34	Q13315	ATM	S1152	E1156Q	1156	Missense	distal	4	no	10.297	10.628	EPSD	GDSC;CCLE	9.540	Up-regulation
Atypical_PIKK_ATM_ATM_ST	Q70CQ2	USP34	Q13315	ATM	S1473	D1475H	1475	Missense	proximal	2	no	12.350	11.289	EPSD	GDSC;CCLE	9.540	Down-regulation
Atypical_PIKK_ATM_ATM_ST	Q70CQ2	USP34	Q13315	ATM	S1751	A1750T	1750	Missense	proximal	-1	no	15.444	15.615	PhosphoSitePlus;EPSD	GDSC	9.540	Up-regulation
Atypical_PIKK_ATM_ATM_ST	Q70CQ2	USP34	Q13315	ATM	S3127	T3122A	3122	Missense	distal	-5	no	9.522	9.603	EPSD	GDSC;CCLE	9.540	Gain
Atypical_PIKK_ATM_ATM_ST	Q70CQ2	USP34	Q13315	ATM	T3195	S3197Y	3197	Missense	proximal	2	no	13.155	12.294	EPSD	GDSC	9.540	Down-regulation
Atypical_PIKK_ATM_ATM_ST	Q13769	THOC5	Q13315	ATM	S307	S307A	307	Missense	central	0	yes	13.722	0.000	EPSD;PhosphoSitePlus	GDSC	9.540	Loss
Atypical_PIKK_ATM_ATM_ST	Q9UQE7	SMC3	Q13315	ATM	S177	R171L	171	Missense	distal	-6	no	10.314	10.207	EPSD	GDSC;CCLE	9.540	Down-regulation
Atypical_PIKK_ATM_ATM_ST	Q9UQE7	SMC3	Q13315	ATM	S177	E170*	170	Missense	distal	-7	no	10.314	8.849	EPSD	GDSC	9.540	Loss
Atypical_PIKK_ATM_ATM_ST	Q9UQE7	SMC3	Q13315	ATM	S383	K388T	388	Missense	distal	5	no	12.017	11.997	EPSD	GDSC;CCLE	9.540	Down-regulation
Atypical_PIKK_ATM_ATM_ST	Q13315	ATM	Q13315	ATM	S1878	H1876Q	1876	Missense	proximal	-2	no	14.356	14.659	EPSD	GDSC;CCLE	9.540	Up-regulation
Atypical_PIKK_ATM_ATM_ST	Q13315	ATM	Q13315	ATM	S1893	F1896L	1896	Missense	distal	3	no	11.705	11.405	EPSD;PhosphoSitePlus	GDSC;CCLE	9.540	Down-regulation
Atypical_PIKK_ATM_ATM_ST	Q13315	ATM	Q13315	ATM	S2242	R2244T	2244	Missense	proximal	2	no	14.683	15.419	EPSD	GDSC;CCLE	9.540	Up-regulation
Atypical_PIKK_ATM_ATM_ST	Q13315	ATM	Q13315	ATM	S2592	V2587M	2587	Missense	distal	-5	no	13.755	13.726	EPSD	GDSC;CCLE	9.540	Down-regulation
Atypical_PIKK_ATM_ATM_ST	Q8N680	ZBTB2	Q13315	ATM	S115	E110K	110	Missense	distal	-5	no	13.086	13.168	PhosphoSitePlus	GDSC;CCLE	9.540	Up-regulation
Atypical_PIKK_ATM_ATM_ST	Q8N680	ZBTB2	Q13315	ATM	S203	T209A	209	Missense	distal	6	no	10.550	10.566	EPSD	GDSC;CCLE	9.540	Up-regulation
Atypical_PIKK_ATM_ATM_ST	Q8N680	ZBTB2	Q13315	ATM	S203	Q199K	199	Missense	distal	-4	no	10.550	10.301	EPSD	GDSC;CCLE	9.540	Down-regulation
Atypical_PIKK_ATM_ATM_ST	Q7L7X3	TAOK1	Q13315	ATM	T502	R495*	495	Missense	distal	-7	no	11.045	10.334	EPSD	GDSC	9.540	Down-regulation
Atypical_PIKK_ATM_ATM_ST	Q7L7X3	TAOK1	Q13315	ATM	T502	R504H	504	Missense	proximal	2	no	11.045	11.361	EPSD	GDSC;CCLE	9.540	Up-regulation
Atypical_PIKK_ATM_ATM_ST	Q7L7X3	TAOK1	Q13315	ATM	T576	L570V	570	Missense	distal	-6	no	9.562	9.594	EPSD	GDSC;CCLE	9.540	Up-regulation
Atypical_PIKK_ATM_ATM_ST	Q7L7X3	TAOK1	Q13315	ATM	T785	A787V	787	Missense	proximal	2	no	14.257	13.948	EPSD;PhosphoSitePlus	GDSC	9.540	Down-regulation
Atypical_PIKK_ATM_ATM_ST	Q7L7X3	TAOK1	Q13315	ATM	S990	T986A	986	Missense	distal	-4	no	14.254	14.127	EPSD;PhosphoSitePlus	GDSC;CCLE	9.540	Down-regulation
Atypical_PIKK_ATM_ATM_ST	P04637	TP53	Q13315	ATM	S37	Q38*	38	Missense	proximal	1	no	15.394	3.870	EPSD	GDSC	9.540	Loss
Atypical_PIKK_ATM_ATM_ST	P04637	TP53	Q13315	ATM	S99	K101*	101	Missense	proximal	2	no	12.537	11.041	EPSD	GDSC	9.540	Down-regulation
Atypical_PIKK_ATM_ATM_ST	P04637	TP53	Q13315	ATM	S99	Q100*	100	Missense	proximal	1	no	12.537	1.012	EPSD	GDSC	9.540	Loss
Atypical_PIKK_ATM_ATM_ST	P04637	TP53	Q13315	ATM	S99	S94*	94	Missense	distal	-5	no	12.537	13.073	EPSD	GDSC	9.540	Up-regulation
Atypical_PIKK_ATM_ATM_ST	P04637	TP53	Q13315	ATM	S106	K101*	101	Missense	distal	-5	no	10.952	11.572	EPSD	GDSC	9.540	Up-regulation
Atypical_PIKK_ATM_ATM_ST	P04637	TP53	Q13315	ATM	S106	Q100*	100	Missense	distal	-6	no	10.952	10.312	EPSD	GDSC	9.540	Down-regulation
Atypical_PIKK_ATM_ATM_ST	P04637	TP53	Q13315	ATM	S106	Y107*	107	Missense	proximal	1	no	10.952	5.144	EPSD	GDSC	9.540	Loss
Atypical_PIKK_ATM_ATM_ST	P04637	TP53	Q13315	ATM	S127	Y126*	126	Missense	proximal	-1	no	9.567	8.885	EPSD	GDSC	9.540	Loss
Atypical_PIKK_ATM_ATM_ST	P04637	TP53	Q13315	ATM	S127	K120*	120	Missense	distal	-7	no	9.567	8.770	EPSD	GDSC	9.540	Loss
Atypical_PIKK_ATM_ATM_ST	P04637	TP53	Q13315	ATM	S183	E180*	180	Missense	distal	-3	no	9.068	10.457	EPSD	GDSC	9.540	Gain
Atypical_PIKK_ATM_ATM_ST	P04637	TP53	Q13315	ATM	S392	G389W	389	Missense	distal	-3	no	9.915	9.948	EPSD	GDSC;CCLE	9.540	Up-regulation
Atypical_PIKK_ATM_ATM_ST	Q9H3D4	TP63	Q13315	ATM	S162	T155I	155	Missense	distal	-7	no	9.666	9.083	EPSD	GDSC;CCLE	9.540	Loss
Atypical_PIKK_ATM_ATM_ST	Q9H3D4	TP63	Q13315	ATM	S455	S457P	457	Missense	proximal	2	no	10.300	9.845	EPSD	GDSC	9.540	Down-regulation
Atypical_PIKK_ATM_ATM_ST	Q9H3D4	TP63	Q13315	ATM	S479	Q485R	485	Missense	distal	6	no	15.147	15.151	PhosphoSitePlus	GDSC;CCLE	9.540	Up-regulation
Atypical_PIKK_ATM_ATM_ST	Q9H3D4	TP63	Q13315	ATM	S479	S477F	477	Missense	proximal	-2	no	15.147	14.247	PhosphoSitePlus	GDSC;CCLE	9.540	Down-regulation
Atypical_PIKK_ATM_ATM_ST	P27707	DCK	Q13315	ATM	T64	N60D	60	Missense	distal	-4	no	13.775	14.699	EPSD	GDSC;CCLE	9.540	Up-regulation
Atypical_PIKK_ATM_ATM_ST	P27707	DCK	Q13315	ATM	S74	N80S	80	Missense	distal	6	no	16.242	16.253	PhosphoSitePlus	GDSC	9.540	Up-regulation
Atypical_PIKK_ATM_ATM_ST	O15111	CHUK	Q13315	ATM	S119	S126C	126	Missense	distal	7	no	12.307	12.359	EPSD	GDSC	9.540	Up-regulation
Atypical_PIKK_ATM_ATM_ST	O15111	CHUK	Q13315	ATM	S473	Q475*	475	Missense	proximal	2	no	13.086	11.072	PhosphoSitePlus	GDSC	9.540	Down-regulation
Atypical_PIKK_ATM_ATM_ST	Q8IX03	WWC1	Q13315	ATM	S654	G658C	658	Missense	distal	4	no	9.262	9.642	EPSD	GDSC;CCLE	9.540	Gain
Atypical_PIKK_ATM_ATM_ST	Q8IX03	WWC1	Q13315	ATM	S785	L784V	784	Missense	proximal	-1	no	11.492	11.204	EPSD	GDSC;CCLE	9.540	Down-regulation
Atypical_PIKK_ATM_ATM_ST	Q8IX03	WWC1	Q13315	ATM	S914	L919F	919	Missense	distal	5	no	15.951	16.093	EPSD	GDSC;CCLE	9.540	Up-regulation
Atypical_PIKK_ATM_ATM_ST	Q8IX03	WWC1	Q13315	ATM	S914	R920Q	920	Missense	distal	6	no	15.951	15.947	EPSD	GDSC;CCLE	9.540	Down-regulation
Atypical_PIKK_ATM_ATM_ST	Q8IX03	WWC1	Q13315	ATM	S936	R941Q	941	Missense	distal	5	no	13.378	13.266	EPSD	GDSC	9.540	Down-regulation
Atypical_PIKK_ATM_ATM_ST	P37275	ZEB1	Q13315	ATM	S280	S285*	285	Missense	distal	5	no	9.387	9.872	EPSD	GDSC	9.540	Gain
Atypical_PIKK_ATM_ATM_ST	P37275	ZEB1	Q13315	ATM	S282	S285*	285	Missense	distal	3	no	10.704	11.451	EPSD	GDSC	9.540	Up-regulation
Atypical_PIKK_ATM_ATM_ST	P37275	ZEB1	Q13315	ATM	S447	A446D	446	Missense	proximal	-1	no	10.921	11.027	EPSD	GDSC;CCLE	9.540	Up-regulation
Atypical_PIKK_ATM_ATM_ST	P37275	ZEB1	Q13315	ATM	T702	P703S	703	Missense	proximal	1	no	10.969	3.994	EPSD	GDSC;CCLE	9.540	Loss
Atypical_PIKK_ATM_ATM_ST	P37275	ZEB1	Q13315	ATM	S704	P703S	703	Missense	proximal	-1	no	10.144	10.436	EPSD	GDSC;CCLE	9.540	Up-regulation
Atypical_PIKK_ATM_ATM_ST	P37275	ZEB1	Q13315	ATM	T716	T722I	722	Missense	distal	6	no	12.764	12.733	EPSD	GDSC;CCLE	9.540	Down-regulation
Atypical_PIKK_ATM_ATM_ST	P37275	ZEB1	Q13315	ATM	T716	Q717*	717	Missense	proximal	1	no	12.764	1.240	EPSD	GDSC	9.540	Loss
Atypical_PIKK_ATM_ATM_ST	P37275	ZEB1	Q13315	ATM	S850	Q854K	854	Missense	distal	4	no	11.233	11.279	EPSD	GDSC	9.540	Up-regulation
Atypical_PIKK_ATM_ATM_ST	P37275	ZEB1	Q13315	ATM	S850	S846A	846	Missense	distal	-4	no	11.233	10.724	EPSD	GDSC;CCLE	9.540	Down-regulation
Atypical_PIKK_ATM_ATM_ST	P37275	ZEB1	Q13315	ATM	S887	P891L	891	Missense	distal	4	no	12.085	12.304	EPSD	GDSC	9.540	Up-regulation
Atypical_PIKK_ATM_ATM_ST	P37275	ZEB1	Q13315	ATM	S887	P891S	891	Missense	distal	4	no	12.085	11.963	EPSD	GDSC;CCLE	9.540	Down-regulation
Atypical_PIKK_ATM_ATM_ST	P37275	ZEB1	Q13315	ATM	T890	P891L	891	Missense	proximal	1	no	9.705	8.150	EPSD	GDSC	9.540	Loss
Atypical_PIKK_ATM_ATM_ST	P37275	ZEB1	Q13315	ATM	T890	P891S	891	Missense	proximal	1	no	9.705	2.729	EPSD	GDSC;CCLE	9.540	Loss
Atypical_PIKK_ATM_ATM_ST	P37275	ZEB1	Q13315	ATM	S995	T996A	996	Missense	proximal	1	no	6.857	9.792	EPSD	GDSC;CCLE	9.540	Gain
Atypical_PIKK_ATM_ATM_ST	P37275	ZEB1	Q13315	ATM	S1100	M1093I	1093	Missense	distal	-7	no	14.055	13.865	EPSD	GDSC;CCLE	9.540	Down-regulation
Atypical_PIKK_ATM_ATM_ST	P37275	ZEB1	Q13315	ATM	S1100	M1093R	1093	Missense	distal	-7	no	14.055	14.131	EPSD	GDSC;CCLE	9.540	Up-regulation
Atypical_PIKK_ATM_ATM_ST	P37275	ZEB1	Q13315	ATM	S1117	G1110D	1110	Missense	distal	-7	no	10.467	10.757	EPSD	GDSC;CCLE	9.540	Up-regulation
Atypical_PIKK_ATM_ATM_ST	Q969R5	L3MBTL2	Q13315	ATM	T98	V96L	96	Missense	proximal	-2	no	9.638	9.913	EPSD	GDSC	9.540	Up-regulation
Atypical_PIKK_ATM_ATM_ST	Q969R5	L3MBTL2	Q13315	ATM	S335	R341H	341	Missense	distal	6	no	13.059	13.043	PhosphoSitePlus	GDSC;CCLE	9.540	Down-regulation
Atypical_PIKK_ATM_ATM_ST	Q969R5	L3MBTL2	Q13315	ATM	S683	D685N	685	Missense	proximal	2	no	9.759	8.738	EPSD	GDSC;CCLE	9.540	Loss
Atypical_PIKK_ATM_ATM_ST	Q969R5	L3MBTL2	Q13315	ATM	S689	D685N	685	Missense	distal	-4	no	12.191	11.267	EPSD	GDSC;CCLE	9.540	Down-regulation
Atypical_PIKK_ATM_ATM_ST	Q9Y4E8	USP15	Q13315	ATM	S229	A232V	232	Missense	distal	3	no	9.671	9.959	EPSD	GDSC	9.540	Up-regulation
Atypical_PIKK_ATM_ATM_ST	Q8IW19	APLF	Q13315	ATM	S144	T140S	140	Missense	distal	-4	no	11.874	12.257	EPSD	GDSC	9.540	Up-regulation
Atypical_PIKK_ATM_ATM_ST	Q9Y2K7	KDM2A	Q13315	ATM	S11	Y10*	10	Missense	proximal	-1	no	15.759	15.077	EPSD	GDSC	9.540	Down-regulation
Atypical_PIKK_ATM_ATM_ST	Q9Y2K7	KDM2A	Q13315	ATM	T632	E625K	625	Missense	distal	-7	no	14.847	14.179	PhosphoSitePlus	GDSC;CCLE	9.540	Down-regulation
Atypical_PIKK_ATM_ATM_ST	Q9Y2K7	KDM2A	Q13315	ATM	S869	A870V	870	Missense	proximal	1	no	11.030	4.908	EPSD	GDSC;CCLE	9.540	Loss
Atypical_PIKK_ATM_ATM_ST	Q9Y2K7	KDM2A	Q13315	ATM	S869	G873W	873	Missense	distal	4	no	11.030	11.227	EPSD	GDSC;CCLE	9.540	Up-regulation
Atypical_PIKK_ATM_ATM_ST	Q02535	ID3	Q13315	ATM	S65	E68*	68	Missense	distal	3	no	14.211	15.134	PhosphoSitePlus	GDSC	9.540	Up-regulation
Atypical_PIKK_ATM_ATM_ST	P46379	BAG6	Q13315	ATM	S16	V21E	21	Missense	distal	5	no	10.294	9.911	EPSD	GDSC	9.540	Down-regulation
Atypical_PIKK_ATM_ATM_ST	P46379	BAG6	Q13315	ATM	S26	V21E	21	Missense	distal	-5	no	15.861	15.583	PhosphoSitePlus;EPSD	GDSC	9.540	Down-regulation
Atypical_PIKK_ATM_ATM_ST	P46379	BAG6	Q13315	ATM	S964	P965T	965	Missense	proximal	1	no	10.101	5.094	EPSD	GDSC;CCLE	9.540	Loss
Atypical_PIKK_ATM_ATM_ST	P46379	BAG6	Q13315	ATM	S996	R997Q	997	Missense	proximal	1	no	6.586	13.238	EPSD	GDSC;CCLE	9.540	Gain
Atypical_PIKK_ATM_ATM_ST	P46379	BAG6	Q13315	ATM	S1081	A1074V	1074	Missense	distal	-7	no	9.713	9.330	EPSD	GDSC;CCLE	9.540	Loss
Atypical_PIKK_ATM_ATM_ST	Q9NUW8	TDP1	Q13315	ATM	S18	S14I	14	Missense	distal	-4	no	9.644	8.933	EPSD	GDSC;CCLE	9.540	Loss
Atypical_PIKK_ATM_ATM_ST	Q9NUW8	TDP1	Q13315	ATM	S18	I12L	12	Missense	distal	-6	no	9.644	9.757	EPSD	GDSC;CCLE	9.540	Up-regulation
Atypical_PIKK_ATM_ATM_ST	Q14683	SMC1A	Q13315	ATM	S703	G707E	707	Missense	distal	4	no	15.804	15.377	EPSD	GDSC;CCLE	9.540	Down-regulation
Atypical_PIKK_ATM_ATM_ST	Q14683	SMC1A	Q13315	ATM	S715	K713T	713	Missense	proximal	-2	no	13.230	13.537	EPSD	GDSC;CCLE	9.540	Up-regulation
Atypical_PIKK_ATM_ATM_ST	P54132	BLM	Q13315	ATM	S144	T150A	150	Missense	distal	6	no	11.497	11.513	EPSD	GDSC;CCLE	9.540	Up-regulation
Atypical_PIKK_ATM_ATM_ST	P54132	BLM	Q13315	ATM	S419	D420H	420	Missense	proximal	1	no	11.145	2.267	EPSD	GDSC;CCLE	9.540	Loss
Atypical_PIKK_ATM_ATM_ST	P54132	BLM	Q13315	ATM	S426	D420H	420	Missense	distal	-6	no	11.389	11.237	EPSD	GDSC;CCLE	9.540	Down-regulation
Atypical_PIKK_ATM_ATM_ST	P54132	BLM	Q13315	ATM	S464	H457R	457	Missense	distal	-7	no	11.465	11.379	EPSD	GDSC;CCLE	9.540	Down-regulation
Atypical_PIKK_ATM_ATM_ST	P54132	BLM	Q13315	ATM	S550	E546D	546	Missense	distal	-4	no	12.539	12.256	EPSD	GDSC;CCLE	9.540	Down-regulation
Atypical_PIKK_ATM_ATM_ST	P54132	BLM	Q13315	ATM	S550	D554V	554	Missense	distal	4	no	12.539	12.637	EPSD	GDSC;CCLE	9.540	Up-regulation
Atypical_PIKK_ATM_ATM_ST	P54132	BLM	Q13315	ATM	S646	S648G	648	Missense	proximal	2	no	10.302	9.444	EPSD	GDSC;CCLE	9.540	Loss
Atypical_PIKK_ATM_ATM_ST	P54132	BLM	Q13315	ATM	S646	K653T	653	Missense	distal	7	no	10.302	10.296	EPSD	GDSC	9.540	Down-regulation
Atypical_PIKK_ATM_ATM_ST	Q14190	SIM2	Q13315	ATM	S35	S41F	41	Missense	distal	6	no	14.063	13.987	EPSD	GDSC;CCLE	9.540	Down-regulation
Atypical_PIKK_ATM_ATM_ST	Q14190	SIM2	Q13315	ATM	S186	S186N	186	Missense	central	0	yes	10.241	0.000	EPSD	GDSC;CCLE	9.540	Loss
Atypical_PIKK_ATM_ATM_ST	Q14190	SIM2	Q13315	ATM	S523	R517W	517	Missense	distal	-6	no	10.969	10.800	EPSD	GDSC	9.540	Down-regulation
Atypical_PIKK_ATM_ATM_ST	P54274	TERF1	Q13315	ATM	T24	D17G	17	Missense	distal	-7	no	9.596	9.306	EPSD	GDSC	9.540	Loss
Atypical_PIKK_ATM_ATM_ST	P54274	TERF1	Q13315	ATM	T24	R19K	19	Missense	distal	-5	no	9.596	9.437	EPSD	GDSC;CCLE	9.540	Loss
Atypical_PIKK_ATM_ATM_ST	P54274	TERF1	Q13315	ATM	S114	H110R	110	Missense	distal	-4	no	9.744	9.614	EPSD	GDSC;CCLE	9.540	Down-regulation
Atypical_PIKK_ATM_ATM_ST	P54274	TERF1	Q13315	ATM	T330	H328R	328	Missense	proximal	-2	no	11.179	11.164	EPSD	GDSC	9.540	Down-regulation
Atypical_PIKK_ATM_ATM_ST	P54274	TERF1	Q13315	ATM	T330	D334E	334	Missense	distal	4	no	11.179	10.673	EPSD	GDSC	9.540	Down-regulation
Atypical_PIKK_ATM_ATM_ST	Q14161	GIT2	Q13315	ATM	T195	Q196H	196	Missense	proximal	1	no	13.965	-0.944	EPSD;PhosphoSitePlus	GDSC;CCLE	9.540	Loss
Atypical_PIKK_ATM_ATM_ST	Q14161	GIT2	Q13315	ATM	S415	N411S	411	Missense	distal	-4	no	12.027	12.955	EPSD	GDSC;CCLE	9.540	Up-regulation
Atypical_PIKK_ATM_ATM_ST	Q14161	GIT2	Q13315	ATM	S590	P588S	588	Missense	proximal	-2	no	10.566	10.803	EPSD	GDSC	9.540	Up-regulation
Atypical_PIKK_ATM_ATM_ST	Q14161	GIT2	Q13315	ATM	S634	S639N	639	Missense	distal	5	no	10.775	10.750	EPSD	GDSC;CCLE	9.540	Down-regulation
Atypical_PIKK_ATM_ATM_ST	Q5XUX0	FBXO31	Q13315	ATM	S400	E399K	399	Missense	proximal	-1	no	14.920	14.518	EPSD	GDSC;CCLE	9.540	Down-regulation
Atypical_PIKK_ATM_ATM_ST	Q5XUX0	FBXO31	Q13315	ATM	S403	E399K	399	Missense	distal	-4	no	11.239	10.267	EPSD	GDSC;CCLE	9.540	Down-regulation
Atypical_PIKK_ATM_ATM_ST	Q92905	COPS5	Q13315	ATM	S320	D325E	325	Missense	distal	5	no	15.790	15.533	PhosphoSitePlus	GDSC;CCLE	9.540	Down-regulation
Atypical_PIKK_ATM_ATM_ST	P15336	ATF2	Q13315	ATM	S328	H331L	331	Missense	distal	3	no	10.429	10.488	EPSD	GDSC;CCLE	9.540	Up-regulation
Atypical_PIKK_ATM_ATM_ST	P15336	ATF2	Q13315	ATM	T336	R342H	342	Missense	distal	6	no	12.972	12.956	EPSD	GDSC;CCLE	9.540	Down-regulation
Atypical_PIKK_ATM_ATM_ST	P15336	ATF2	Q13315	ATM	T336	H331L	331	Missense	distal	-5	no	12.972	12.946	EPSD	GDSC;CCLE	9.540	Down-regulation
Atypical_PIKK_ATM_ATM_ST	P15336	ATF2	Q13315	ATM	S438	D433H	433	Missense	distal	-5	no	10.118	10.378	EPSD	GDSC;CCLE	9.540	Up-regulation
Atypical_PIKK_ATM_ATM_ST	Q14676	MDC1	Q13315	ATM	T4	E2D	2	Missense	proximal	-2	no	11.183	10.704	PhosphoSitePlus;EPSD	GDSC;CCLE	9.540	Down-regulation
Atypical_PIKK_ATM_ATM_ST	Q14676	MDC1	Q13315	ATM	T17	E14*	14	Missense	distal	-3	no	8.252	9.641	EPSD	GDSC	9.540	Gain
Atypical_PIKK_ATM_ATM_ST	Q14676	MDC1	Q13315	ATM	S21	S23F	23	Missense	proximal	2	no	11.922	10.443	EPSD	GDSC;CCLE	9.540	Down-regulation
Atypical_PIKK_ATM_ATM_ST	Q14676	MDC1	Q13315	ATM	S21	E14*	14	Missense	distal	-7	no	11.922	10.457	EPSD	GDSC	9.540	Down-regulation
Atypical_PIKK_ATM_ATM_ST	Q14676	MDC1	Q13315	ATM	S23	S23F	23	Missense	central	0	yes	11.007	0.000	EPSD	GDSC;CCLE	9.540	Loss
Atypical_PIKK_ATM_ATM_ST	Q14676	MDC1	Q13315	ATM	S141	R142Q	142	Missense	proximal	1	no	4.728	11.380	EPSD	GDSC;CCLE	9.540	Gain
Atypical_PIKK_ATM_ATM_ST	Q14676	MDC1	Q13315	ATM	T157	R161G	161	Missense	distal	4	no	14.107	14.054	EPSD	GDSC;CCLE	9.540	Down-regulation
Atypical_PIKK_ATM_ATM_ST	Q14676	MDC1	Q13315	ATM	S372	L369M	369	Missense	distal	-3	no	13.561	13.707	EPSD	GDSC;CCLE	9.540	Up-regulation
Atypical_PIKK_ATM_ATM_ST	Q14676	MDC1	Q13315	ATM	S505	D502N	502	Missense	distal	-3	no	10.156	9.883	EPSD	GDSC;CCLE	9.540	Down-regulation
Atypical_PIKK_ATM_ATM_ST	Q14676	MDC1	Q13315	ATM	S505	P506H	506	Missense	proximal	1	no	10.156	0.049	EPSD	GDSC;CCLE	9.540	Loss
Atypical_PIKK_ATM_ATM_ST	Q14676	MDC1	Q13315	ATM	S505	R512K	512	Missense	distal	7	no	10.156	10.144	EPSD	GDSC;CCLE	9.540	Down-regulation
Atypical_PIKK_ATM_ATM_ST	Q14676	MDC1	Q13315	ATM	S513	P506H	506	Missense	distal	-7	no	14.104	14.027	EPSD	GDSC;CCLE	9.540	Down-regulation
Atypical_PIKK_ATM_ATM_ST	Q14676	MDC1	Q13315	ATM	S513	R512K	512	Missense	proximal	-1	no	14.104	14.286	EPSD	GDSC;CCLE	9.540	Up-regulation
Atypical_PIKK_ATM_ATM_ST	Q14676	MDC1	Q13315	ATM	S641	L648M	648	Missense	distal	7	no	9.770	9.784	EPSD	GDSC;CCLE	9.540	Up-regulation
Atypical_PIKK_ATM_ATM_ST	Q14676	MDC1	Q13315	ATM	S882	E884K	884	Missense	proximal	2	no	9.638	8.307	EPSD	GDSC	9.540	Loss
Atypical_PIKK_ATM_ATM_ST	Q14676	MDC1	Q13315	ATM	S882	R885T	885	Missense	distal	3	no	9.638	9.533	EPSD	GDSC;CCLE	9.540	Loss
Atypical_PIKK_ATM_ATM_ST	Q14676	MDC1	Q13315	ATM	S882	R887M	887	Missense	distal	5	no	9.638	9.657	EPSD	GDSC;CCLE	9.540	Up-regulation
Atypical_PIKK_ATM_ATM_ST	Q14676	MDC1	Q13315	ATM	S1055	P1052S	1052	Missense	distal	-3	no	14.808	14.612	EPSD	GDSC;CCLE	9.540	Down-regulation
Atypical_PIKK_ATM_ATM_ST	Q14676	MDC1	Q13315	ATM	S1057	P1052S	1052	Missense	distal	-5	no	13.905	13.902	EPSD	GDSC;CCLE	9.540	Down-regulation
Atypical_PIKK_ATM_ATM_ST	Q14676	MDC1	Q13315	ATM	S1086	R1082M	1082	Missense	distal	-4	no	14.346	14.149	EPSD	GDSC;CCLE	9.540	Down-regulation
Atypical_PIKK_ATM_ATM_ST	Q14676	MDC1	Q13315	ATM	S1086	Q1083H	1083	Missense	distal	-3	no	14.346	14.476	EPSD	GDSC;CCLE	9.540	Up-regulation
Atypical_PIKK_ATM_ATM_ST	Q14676	MDC1	Q13315	ATM	S1130	T1131P	1131	Missense	proximal	1	no	5.806	10.813	EPSD	GDSC	9.540	Gain
Atypical_PIKK_ATM_ATM_ST	Q14676	MDC1	Q13315	ATM	S1184	T1183I	1183	Missense	proximal	-1	no	13.570	13.339	EPSD	GDSC;CCLE	9.540	Down-regulation
Atypical_PIKK_ATM_ATM_ST	Q14676	MDC1	Q13315	ATM	T1198	T1205A	1205	Missense	distal	7	no	10.825	10.839	EPSD	GDSC	9.540	Up-regulation
Atypical_PIKK_ATM_ATM_ST	Q14676	MDC1	Q13315	ATM	S1225	A1227V	1227	Missense	proximal	2	no	13.833	13.524	EPSD	GDSC	9.540	Down-regulation
Atypical_PIKK_ATM_ATM_ST	Q14676	MDC1	Q13315	ATM	T1239	N1233S	1233	Missense	distal	-6	no	10.798	10.914	EPSD	GDSC	9.540	Up-regulation
Atypical_PIKK_ATM_ATM_ST	Q14676	MDC1	Q13315	ATM	T1280	V1278G	1278	Missense	proximal	-2	no	10.583	10.805	EPSD	GDSC	9.540	Up-regulation
Atypical_PIKK_ATM_ATM_ST	Q14676	MDC1	Q13315	ATM	T1526	V1524L	1524	Missense	proximal	-2	no	10.241	10.516	EPSD	GDSC	9.540	Up-regulation
Atypical_PIKK_ATM_ATM_ST	Q14676	MDC1	Q13315	ATM	T1526	P1527H	1527	Missense	proximal	1	no	10.241	0.133	EPSD	GDSC	9.540	Loss
Atypical_PIKK_ATM_ATM_ST	Q14676	MDC1	Q13315	ATM	T1622	T1623P	1623	Missense	proximal	1	no	5.705	10.712	EPSD	GDSC	9.540	Gain
Atypical_PIKK_ATM_ATM_ST	Q16665	HIF1A	Q13315	ATM	S510	Q508*	508	Missense	proximal	-2	no	11.439	10.643	EPSD	GDSC	9.540	Down-regulation
Atypical_PIKK_ATM_ATM_ST	Q16665	HIF1A	Q13315	ATM	S515	Q508*	508	Missense	distal	-7	no	9.638	8.728	EPSD	GDSC	9.540	Loss
Atypical_PIKK_ATM_ATM_ST	Q16665	HIF1A	Q13315	ATM	S657	Y659N	659	Missense	proximal	2	no	11.908	12.128	EPSD	GDSC;CCLE	9.540	Up-regulation
Atypical_PIKK_ATM_ATM_ST	Q16665	HIF1A	Q13315	ATM	S668	K674N	674	Missense	distal	6	no	10.294	10.305	EPSD	GDSC;CCLE	9.540	Up-regulation
Atypical_PIKK_ATM_ATM_ST	Q14694	USP10	Q13315	ATM	S35	S28L	28	Missense	distal	-7	no	9.580	8.992	EPSD	GDSC;CCLE	9.540	Loss
Atypical_PIKK_ATM_ATM_ST	Q14694	USP10	Q13315	ATM	S337	K340R	340	Missense	distal	3	no	15.641	15.713	EPSD;PhosphoSitePlus	GDSC;CCLE	9.540	Up-regulation
Atypical_PIKK_ATM_ATM_ST	Q92878	RAD50	Q13315	ATM	S635	L642V	642	Missense	distal	7	no	14.965	14.995	PhosphoSitePlus	GDSC;CCLE	9.540	Up-regulation
Atypical_PIKK_ATM_ATM_ST	Q92878	RAD50	Q13315	ATM	S1297	V1300G	1300	Missense	distal	3	no	9.876	9.662	EPSD	GDSC;CCLE	9.540	Down-regulation
Atypical_PIKK_ATM_ATM_ST	Q13263	TRIM28	Q13315	ATM	S223	C224Y	224	Missense	proximal	1	no	5.244	11.739	EPSD	GDSC;CCLE	9.540	Gain
Atypical_PIKK_ATM_ATM_ST	Q13263	TRIM28	Q13315	ATM	S501	Q502H	502	Missense	proximal	1	no	14.167	-0.742	EPSD	GDSC;CCLE	9.540	Loss
Atypical_PIKK_ATM_ATM_ST	Q13263	TRIM28	Q13315	ATM	S501	V505I	505	Missense	distal	4	no	14.167	14.524	EPSD	GDSC;CCLE	9.540	Up-regulation
Atypical_PIKK_ATM_ATM_ST	Q13263	TRIM28	Q13315	ATM	S594	S601L	601	Missense	distal	7	no	10.834	10.853	EPSD	GDSC;CCLE	9.540	Up-regulation
Atypical_PIKK_ATM_ATM_ST	Q13263	TRIM28	Q13315	ATM	S757	S752*	752	Missense	distal	-5	no	9.585	10.121	EPSD	GDSC	9.540	Up-regulation
Atypical_PIKK_ATM_ATM_ST	Q9NZM5	NOP53	Q13315	ATM	S233	P236S	236	Missense	distal	3	no	15.156	15.004	EPSD;PhosphoSitePlus	GDSC	9.540	Down-regulation
Atypical_PIKK_ATM_ATM_ST	Q9H9Q4	NHEJ1	Q13315	ATM	S55	R57Q	57	Missense	proximal	2	no	12.475	13.170	EPSD	GDSC	9.540	Up-regulation
Atypical_PIKK_ATM_ATM_ST	Q9H9Q4	NHEJ1	Q13315	ATM	S245	S243I	243	Missense	proximal	-2	no	10.670	9.980	EPSD	GDSC;CCLE	9.540	Down-regulation
Atypical_PIKK_ATM_ATM_ST	Q14191	WRN	Q13315	ATM	S440	D433G	433	Missense	distal	-7	no	10.013	9.723	EPSD	GDSC;CCLE	9.540	Down-regulation
Atypical_PIKK_ATM_ATM_ST	Q14191	WRN	Q13315	ATM	T777	T781I	781	Missense	distal	4	no	11.468	12.044	EPSD	GDSC	9.540	Up-regulation
Atypical_PIKK_ATM_ATM_ST	Q14191	WRN	Q13315	ATM	T777	T781A	781	Missense	distal	4	no	11.468	11.033	EPSD	GDSC;CCLE	9.540	Down-regulation
Atypical_PIKK_ATM_ATM_ST	Q14191	WRN	Q13315	ATM	S1141	S1141L	1141	Missense	central	0	yes	16.725	0.000	PhosphoSitePlus	GDSC	9.540	Loss
Atypical_PIKK_ATM_ATM_ST	Q14191	WRN	Q13315	ATM	S1292	G1298V	1298	Missense	distal	6	no	14.612	14.607	EPSD	GDSC	9.540	Down-regulation
Atypical_PIKK_ATM_ATM_ST	Q13362	PPP2R5C	Q13315	ATM	S520	G523C	523	Missense	distal	3	no	14.823	15.113	PhosphoSitePlus	GDSC;CCLE	9.540	Up-regulation
Atypical_PIKK_ATM_ATM_ST	Q13362	PPP2R5C	Q13315	ATM	S520	G523S	523	Missense	distal	3	no	14.823	14.692	PhosphoSitePlus	GDSC;CCLE	9.540	Down-regulation
Atypical_PIKK_ATM_ATM_ST	Q14674	ESPL1	Q13315	ATM	S244	A248V	248	Missense	distal	4	no	10.020	10.673	EPSD	GDSC	9.540	Up-regulation
Atypical_PIKK_ATM_ATM_ST	Q14674	ESPL1	Q13315	ATM	S244	S238N	238	Missense	distal	-6	no	10.020	9.904	EPSD	GDSC;CCLE	9.540	Down-regulation
Atypical_PIKK_ATM_ATM_ST	Q14674	ESPL1	Q13315	ATM	S244	L242R	242	Missense	proximal	-2	no	10.020	9.967	EPSD	GDSC;CCLE	9.540	Down-regulation
Atypical_PIKK_ATM_ATM_ST	Q14674	ESPL1	Q13315	ATM	S1126	T1123I	1123	Missense	distal	-3	no	9.438	10.176	EPSD	GDSC;CCLE	9.540	Gain
Atypical_PIKK_ATM_ATM_ST	Q14674	ESPL1	Q13315	ATM	S1406	S1406L	1406	Missense	central	0	yes	9.671	0.000	EPSD	GDSC;CCLE	9.540	Loss
Atypical_PIKK_ATM_ATM_ST	Q9UER7	DAXX	Q13315	ATM	S33	A32T	32	Missense	proximal	-1	no	9.816	9.986	EPSD	GDSC;CCLE	9.540	Up-regulation
Atypical_PIKK_ATM_ATM_ST	Q9UER7	DAXX	Q13315	ATM	S176	S176A	176	Missense	central	0	yes	14.524	0.000	EPSD	GDSC;CCLE	9.540	Loss
Atypical_PIKK_ATM_ATM_ST	Q9UER7	DAXX	Q13315	ATM	S176	R182H	182	Missense	distal	6	no	14.524	14.509	EPSD	GDSC;CCLE	9.540	Down-regulation
Atypical_PIKK_ATM_ATM_ST	Q9UER7	DAXX	Q13315	ATM	S424	C427Y	427	Missense	distal	3	no	15.255	15.075	EPSD	GDSC;CCLE	9.540	Down-regulation
Atypical_PIKK_ATM_ATM_ST	Q9UER7	DAXX	Q13315	ATM	S688	D687V	687	Missense	proximal	-1	no	9.994	9.625	EPSD	GDSC	9.540	Down-regulation
Atypical_PIKK_ATM_ATM_ST	Q9UER7	DAXX	Q13315	ATM	T726	V724M	724	Missense	proximal	-2	no	12.260	12.486	EPSD	GDSC	9.540	Up-regulation
Atypical_PIKK_ATM_ATM_ST	Q5UIP0	RIF1	Q13315	ATM	S111	R116C	116	Missense	distal	5	no	9.942	10.003	EPSD	GDSC	9.540	Up-regulation
Atypical_PIKK_ATM_ATM_ST	Q5UIP0	RIF1	Q13315	ATM	S402	S402F	402	Missense	central	0	yes	9.586	0.000	EPSD	GDSC;CCLE	9.540	Loss
Atypical_PIKK_ATM_ATM_ST	Q5UIP0	RIF1	Q13315	ATM	S989	T986A	986	Missense	distal	-3	no	16.596	16.219	EPSD	GDSC	9.540	Down-regulation
Atypical_PIKK_ATM_ATM_ST	Q5UIP0	RIF1	Q13315	ATM	S989	L991V	991	Missense	proximal	2	no	16.596	16.948	EPSD	GDSC;CCLE	9.540	Up-regulation
Atypical_PIKK_ATM_ATM_ST	Q5UIP0	RIF1	Q13315	ATM	S1089	S1089C	1089	Missense	central	0	yes	14.947	0.000	EPSD	GDSC;CCLE	9.540	Loss
Atypical_PIKK_ATM_ATM_ST	Q5UIP0	RIF1	Q13315	ATM	S1098	Y1097C	1097	Missense	proximal	-1	no	14.061	13.910	EPSD	GDSC	9.540	Down-regulation
Atypical_PIKK_ATM_ATM_ST	Q5UIP0	RIF1	Q13315	ATM	S1098	P1102L	1102	Missense	distal	4	no	14.061	14.280	EPSD	GDSC;CCLE	9.540	Up-regulation
Atypical_PIKK_ATM_ATM_ST	Q5UIP0	RIF1	Q13315	ATM	S1098	E1101D	1101	Missense	distal	3	no	14.061	14.420	EPSD	GDSC	9.540	Up-regulation
Atypical_PIKK_ATM_ATM_ST	Q5UIP0	RIF1	Q13315	ATM	S1236	N1241D	1241	Missense	distal	5	no	11.274	11.386	EPSD	GDSC	9.540	Up-regulation
Atypical_PIKK_ATM_ATM_ST	Q5UIP0	RIF1	Q13315	ATM	S1238	N1241D	1241	Missense	distal	3	no	11.402	11.385	EPSD	GDSC	9.540	Down-regulation
Atypical_PIKK_ATM_ATM_ST	Q5UIP0	RIF1	Q13315	ATM	S1454	P1455T	1455	Missense	proximal	1	no	11.088	6.081	EPSD	GDSC;CCLE	9.540	Loss
Atypical_PIKK_ATM_ATM_ST	Q5UIP0	RIF1	Q13315	ATM	T1518	D1516N	1516	Missense	proximal	-2	no	14.892	15.011	EPSD	GDSC;CCLE	9.540	Up-regulation
Atypical_PIKK_ATM_ATM_ST	Q5UIP0	RIF1	Q13315	ATM	S1554	S1554F	1554	Missense	central	0	yes	9.723	0.000	EPSD	GDSC;CCLE	9.540	Loss
Atypical_PIKK_ATM_ATM_ST	Q5UIP0	RIF1	Q13315	ATM	S1557	S1554F	1554	Missense	distal	-3	no	8.865	9.936	EPSD	GDSC;CCLE	9.540	Gain
Atypical_PIKK_ATM_ATM_ST	Q5UIP0	RIF1	Q13315	ATM	S1760	E1758G	1758	Missense	proximal	-2	no	11.194	10.571	EPSD	GDSC	9.540	Down-regulation
Atypical_PIKK_ATM_ATM_ST	Q5UIP0	RIF1	Q13315	ATM	S1772	E1775*	1775	Missense	distal	3	no	9.763	10.685	EPSD	GDSC	9.540	Up-regulation
Atypical_PIKK_ATM_ATM_ST	Q5UIP0	RIF1	Q13315	ATM	S1774	E1775*	1775	Missense	proximal	1	no	9.863	4.235	EPSD	GDSC	9.540	Loss
Atypical_PIKK_ATM_ATM_ST	Q5UIP0	RIF1	Q13315	ATM	S1777	E1775*	1775	Missense	proximal	-2	no	14.969	13.868	EPSD	GDSC	9.540	Down-regulation
Atypical_PIKK_ATM_ATM_ST	Q5UIP0	RIF1	Q13315	ATM	S1851	E1857*	1857	Missense	distal	6	no	14.608	14.472	PhosphoSitePlus	GDSC	9.540	Down-regulation
Atypical_PIKK_ATM_ATM_ST	Q5UIP0	RIF1	Q13315	ATM	S1854	E1857*	1857	Missense	distal	3	no	11.330	12.253	EPSD	GDSC	9.540	Up-regulation
Atypical_PIKK_ATM_ATM_ST	Q13541	EIF4EBP1	Q13315	ATM	S101	G108S	108	Missense	distal	7	no	12.020	11.978	EPSD	GDSC;CCLE	9.540	Down-regulation
Atypical_PIKK_ATM_ATM_ST	Q13541	EIF4EBP1	Q13315	ATM	S112	G108S	108	Missense	distal	-4	no	15.382	16.171	EPSD	GDSC;CCLE	9.540	Up-regulation
Atypical_PIKK_ATM_ATM_ST	O15164	TRIM24	Q13315	ATM	S445	V440I	440	Missense	distal	-5	no	14.715	14.716	EPSD	GDSC	9.540	Up-regulation
Atypical_PIKK_ATM_ATM_ST	O15164	TRIM24	Q13315	ATM	S445	N444S	444	Missense	proximal	-1	no	14.715	14.770	EPSD	GDSC;CCLE	9.540	Up-regulation
Atypical_PIKK_ATM_ATM_ST	O15164	TRIM24	Q13315	ATM	T461	F459C	459	Missense	proximal	-2	no	12.153	12.591	EPSD	GDSC;CCLE	9.540	Up-regulation
Atypical_PIKK_ATM_ATM_ST	O15164	TRIM24	Q13315	ATM	S762	S762Y	762	Missense	central	0	yes	10.008	0.000	EPSD	GDSC;CCLE	9.540	Loss
Atypical_PIKK_ATM_ATM_ST	O15164	TRIM24	Q13315	ATM	S768	S771P	771	Missense	distal	3	no	14.556	14.708	PhosphoSitePlus	GDSC	9.540	Up-regulation
Atypical_PIKK_ATM_ATM_ST	O15164	TRIM24	Q13315	ATM	S768	S762Y	762	Missense	distal	-6	no	14.556	14.307	PhosphoSitePlus	GDSC;CCLE	9.540	Down-regulation
Atypical_PIKK_ATM_ATM_ST	O15164	TRIM24	Q13315	ATM	S1019	E1018G	1018	Missense	proximal	-1	no	10.117	9.715	EPSD	GDSC;CCLE	9.540	Down-regulation
Atypical_PIKK_ATM_ATM_ST	O15164	TRIM24	Q13315	ATM	S1019	E1018*	1018	Missense	proximal	-1	no	10.117	9.176	EPSD	GDSC	9.540	Loss
Atypical_PIKK_ATM_ATM_ST	O15164	TRIM24	Q13315	ATM	S1025	E1018G	1018	Missense	distal	-7	no	11.093	10.225	EPSD	GDSC;CCLE	9.540	Down-regulation
Atypical_PIKK_ATM_ATM_ST	O15164	TRIM24	Q13315	ATM	S1025	E1018*	1018	Missense	distal	-7	no	11.093	9.628	EPSD	GDSC	9.540	Down-regulation
Atypical_PIKK_ATM_ATM_ST	Q9NY61	AATF	Q13315	ATM	S104	G111E	111	Missense	distal	7	no	10.401	10.355	EPSD	GDSC	9.540	Down-regulation
Atypical_PIKK_ATM_ATM_ST	Q9NY61	AATF	Q13315	ATM	S109	G111E	111	Missense	proximal	2	no	9.710	11.080	EPSD	GDSC	9.540	Up-regulation
Atypical_PIKK_ATM_ATM_ST	Q9NY61	AATF	Q13315	ATM	S189	A186V	186	Missense	distal	-3	no	15.955	16.819	PhosphoSitePlus	GDSC;CCLE	9.540	Up-regulation
Atypical_PIKK_ATM_ATM_ST	Q9NY61	AATF	Q13315	ATM	S316	A314T	314	Missense	proximal	-2	no	10.239	10.339	EPSD	GDSC;CCLE	9.540	Up-regulation
Atypical_PIKK_ATM_ATM_ST	Q9NY61	AATF	Q13315	ATM	T394	E389Q	389	Missense	distal	-5	no	11.983	12.015	EPSD	GDSC;CCLE	9.540	Up-regulation
Atypical_PIKK_ATM_ATM_ST	P51532	SMARCA4	Q13315	ATM	S117	Y120S	120	Missense	distal	3	no	13.976	13.735	EPSD	GDSC	9.540	Down-regulation
Atypical_PIKK_ATM_ATM_ST	P51532	SMARCA4	Q13315	ATM	S323	A321T	321	Missense	proximal	-2	no	10.178	10.278	EPSD	GDSC;CCLE	9.540	Up-regulation
Atypical_PIKK_ATM_ATM_ST	P51532	SMARCA4	Q13315	ATM	S610	E608*	608	Missense	proximal	-2	no	13.887	12.785	EPSD	GDSC	9.540	Down-regulation
Atypical_PIKK_ATM_ATM_ST	P51532	SMARCA4	Q13315	ATM	S610	G603D	603	Missense	distal	-7	no	13.887	14.177	EPSD	GDSC;CCLE	9.540	Up-regulation
Atypical_PIKK_ATM_ATM_ST	P51532	SMARCA4	Q13315	ATM	S657	S655P	655	Missense	proximal	-2	no	10.774	10.537	EPSD	GDSC;CCLE	9.540	Down-regulation
Atypical_PIKK_ATM_ATM_ST	P51532	SMARCA4	Q13315	ATM	S662	S655P	655	Missense	distal	-7	no	9.942	9.706	EPSD	GDSC;CCLE	9.540	Down-regulation
Atypical_PIKK_ATM_ATM_ST	P51532	SMARCA4	Q13315	ATM	S833	A826S	826	Missense	distal	-7	no	10.726	10.822	EPSD	GDSC;CCLE	9.540	Up-regulation
Atypical_PIKK_ATM_ATM_ST	P51532	SMARCA4	Q13315	ATM	S1380	V1377G	1377	Missense	distal	-3	no	9.956	9.816	EPSD	GDSC	9.540	Down-regulation
Atypical_PIKK_ATM_ATM_ST	Q03111	MLLT1	Q13315	ATM	S209	E203Q	203	Missense	distal	-6	no	9.721	9.496	EPSD	GDSC;CCLE	9.540	Loss
Atypical_PIKK_ATM_ATM_ST	Q03111	MLLT1	Q13315	ATM	S375	S369F	369	Missense	distal	-6	no	10.488	9.957	EPSD	GDSC;CCLE	9.540	Down-regulation
Atypical_PIKK_ATM_ATM_ST	Q03111	MLLT1	Q13315	ATM	S475	S475R	475	Missense	central	0	yes	12.248	0.000	EPSD	GDSC;CCLE	9.540	Loss
Atypical_PIKK_ATM_ATM_ST	Q9HB75	PIDD1	Q13315	ATM	S299	S304G	304	Missense	distal	5	no	11.416	11.594	EPSD	GDSC	9.540	Up-regulation
Atypical_PIKK_ATM_ATM_ST	Q16204	CCDC6	Q13315	ATM	S20	N16S	16	Missense	distal	-4	no	8.892	9.820	EPSD	GDSC;CCLE	9.540	Gain
Atypical_PIKK_ATM_ATM_ST	Q16204	CCDC6	Q13315	ATM	S419	P412A	412	Missense	distal	-7	no	13.282	13.421	EPSD	GDSC;CCLE	9.540	Up-regulation
Atypical_PIKK_ATM_ATM_ST	Q16204	CCDC6	Q13315	ATM	S459	S459L	459	Missense	central	0	yes	13.636	0.000	EPSD	GDSC	9.540	Loss
Atypical_PIKK_ATM_ATM_ST	Q16204	CCDC6	Q13315	ATM	S464	S459L	459	Missense	distal	-5	no	14.429	14.452	EPSD	GDSC	9.540	Up-regulation
Atypical_PIKK_ATM_ATM_ST	Q15109	AGER	Q13315	ATM	S391	G397R	397	Missense	distal	6	no	11.086	11.087	PhosphoSitePlus	GDSC	9.540	Up-regulation
Atypical_PIKK_ATM_ATM_ST	Q99638	RAD9A	Q13315	ATM	S272	S277F	277	Missense	distal	5	no	14.144	14.450	PhosphoSitePlus	GDSC;CCLE	9.540	Up-regulation
Atypical_PIKK_ATM_ATM_ST	Q99638	RAD9A	Q13315	ATM	S341	P339S	339	Missense	proximal	-2	no	9.460	9.697	EPSD	GDSC;CCLE	9.540	Gain
Atypical_PIKK_ATM_ATM_ST	Q99638	RAD9A	Q13315	ATM	T355	P357Q	357	Missense	proximal	2	no	9.761	9.914	EPSD	GDSC;CCLE	9.540	Up-regulation
Atypical_PIKK_ATM_ATM_ST	Q99638	RAD9A	Q13315	ATM	T355	S350G	350	Missense	distal	-5	no	9.761	9.816	EPSD	GDSC;CCLE	9.540	Up-regulation
Atypical_PIKK_ATM_ATM_ST	Q99638	RAD9A	Q13315	ATM	S375	R374C	374	Missense	proximal	-1	no	9.458	9.633	EPSD	GDSC;CCLE	9.540	Gain
Atypical_PIKK_ATM_ATM_ST	Q99638	RAD9A	Q13315	ATM	S375	P379L	379	Missense	distal	4	no	9.458	9.677	EPSD	GDSC;CCLE	9.540	Gain
Atypical_PIKK_ATM_ATM_ST	P40692	MLH1	Q13315	ATM	S692	Q689R	689	Missense	distal	-3	no	10.216	10.990	EPSD	GDSC	9.540	Up-regulation
Atypical_PIKK_ATM_ATM_ST	O43683	BUB1	Q13315	ATM	S307	H308Y	308	Missense	proximal	1	no	0.397	9.591	EPSD	GDSC;CCLE	9.540	Gain
Atypical_PIKK_ATM_ATM_ST	O43683	BUB1	Q13315	ATM	S314	E316V	316	Missense	proximal	2	no	14.746	13.343	PhosphoSitePlus	GDSC;CCLE	9.540	Down-regulation
Atypical_PIKK_ATM_ATM_ST	O43683	BUB1	Q13315	ATM	S314	H308Y	308	Missense	distal	-6	no	14.746	14.676	PhosphoSitePlus	GDSC;CCLE	9.540	Down-regulation
Atypical_PIKK_ATM_ATM_ST	O43683	BUB1	Q13315	ATM	S379	S375F	375	Missense	distal	-4	no	16.400	15.001	EPSD	GDSC;CCLE	9.540	Down-regulation
Atypical_PIKK_ATM_ATM_ST	O43683	BUB1	Q13315	ATM	S459	V462M	462	Missense	distal	3	no	12.629	12.541	EPSD	GDSC;CCLE	9.540	Down-regulation
Atypical_PIKK_ATM_ATM_ST	O43683	BUB1	Q13315	ATM	S459	P460H	460	Missense	proximal	1	no	12.629	2.522	EPSD	GDSC;CCLE	9.540	Loss
Atypical_PIKK_ATM_ATM_ST	O00213	APBB1	Q13315	ATM	S118	L116P	116	Missense	proximal	-2	no	9.921	10.074	EPSD	GDSC;CCLE	9.540	Up-regulation
Atypical_PIKK_ATM_ATM_ST	O00213	APBB1	Q13315	ATM	S205	S205C	205	Missense	central	0	yes	9.690	0.000	EPSD	GDSC;CCLE	9.540	Loss
Atypical_PIKK_ATM_ATM_ST	O00213	APBB1	Q13315	ATM	S289	S287C	287	Missense	proximal	-2	no	15.539	15.078	EPSD	GDSC;CCLE	9.540	Down-regulation
Atypical_PIKK_ATM_ATM_ST	O00213	APBB1	Q13315	ATM	S289	S292I	292	Missense	distal	3	no	15.539	16.041	EPSD	GDSC;CCLE	9.540	Up-regulation
Atypical_PIKK_ATM_ATM_ST	Q86U86	PBRM1	Q13315	ATM	S89	Q90E	90	Missense	proximal	1	no	13.544	7.647	EPSD	GDSC;CCLE	9.540	Loss
Atypical_PIKK_ATM_ATM_ST	Q86U86	PBRM1	Q13315	ATM	S178	K183*	183	Missense	distal	5	no	11.661	12.143	EPSD	GDSC	9.540	Up-regulation
Atypical_PIKK_ATM_ATM_ST	Q86U86	PBRM1	Q13315	ATM	S178	T172I	172	Missense	distal	-6	no	11.661	11.330	EPSD	GDSC;CCLE	9.540	Down-regulation
Atypical_PIKK_ATM_ATM_ST	Q86U86	PBRM1	Q13315	ATM	S681	R678*	678	Missense	distal	-3	no	11.273	11.764	EPSD	GDSC	9.540	Up-regulation
Atypical_PIKK_ATM_ATM_ST	Q99504	EYA3	Q13315	ATM	S256	R253K	253	Missense	distal	-3	no	10.141	9.308	EPSD	GDSC;CCLE	9.540	Loss
Atypical_PIKK_ATM_ATM_ST	Q15797	SMAD1	Q13315	ATM	S239	M246I	246	Missense	distal	7	no	14.556	14.554	PhosphoSitePlus	GDSC;CCLE	9.540	Down-regulation
TK_Trk_NTRK1_Y	P29353	SHC1	P04629	NTRK1	Y349	Y349H	349	Missense	central	0	yes	0.000	0.000	EPSD	GDSC;CCLE	0.000	Loss
TK_Trk_NTRK1_Y	P35222	CTNNB1	P04629	NTRK1	Y670	Y670*	670	Missense	central	0	yes	0.000	0.000	EPSD	GDSC	0.000	Loss
CMGC_MAPK_p38_MAPK13_ST	O00418	EEF2K	O15264	MAPK13	S74	Y69H	69	Missense	distal	-5	no	50.260	50.171	EPSD	GDSC;CCLE	38.013	Down-regulation
CMGC_MAPK_p38_MAPK13_ST	O00418	EEF2K	O15264	MAPK13	S627	G623S	623	Missense	distal	-4	no	37.639	40.186	EPSD	GDSC	38.013	Gain
CMGC_MAPK_p38_MAPK13_ST	P10636	MAPT	O15264	MAPK13	S46	Q49H	49	Missense	distal	3	no	46.241	46.452	EPSD	GDSC	38.013	Up-regulation
CMGC_MAPK_p38_MAPK13_ST	P10636	MAPT	O15264	MAPK13	S46	A41V	41	Missense	distal	-5	no	46.241	46.274	EPSD	GDSC;CCLE	38.013	Up-regulation
CMGC_MAPK_p38_MAPK13_ST	P10636	MAPT	O15264	MAPK13	T50	Q49H	49	Missense	proximal	-1	no	55.525	54.948	EPSD	GDSC	38.013	Down-regulation
CMGC_MAPK_p38_MAPK13_ST	P10636	MAPT	O15264	MAPK13	S228	R222H	222	Missense	distal	-6	no	46.272	45.721	EPSD	GDSC;CCLE	38.013	Down-regulation
CMGC_MAPK_p38_MAPK13_ST	P10636	MAPT	O15264	MAPK13	T470	A475V	475	Missense	distal	5	no	55.325	55.650	EPSD	GDSC;CCLE	38.013	Up-regulation
CMGC_MAPK_p38_MAPK13_ST	P10636	MAPT	O15264	MAPK13	S739	S739C	739	Missense	central	0	yes	54.284	0.000	EPSD	GDSC	38.013	Loss
CMGC_MAPK_p38_MAPK13_ST	Q00613	HSF1	O15264	MAPK13	S121	N114S	114	Missense	distal	-7	no	43.545	43.843	EPSD	GDSC;CCLE	38.013	Up-regulation
CMGC_MAPK_p38_MAPK13_ST	Q00613	HSF1	O15264	MAPK13	S292	R296H	296	Missense	distal	4	no	41.730	41.919	EPSD	GDSC;CCLE	38.013	Up-regulation
CMGC_MAPK_p38_MAPK13_ST	Q00613	HSF1	O15264	MAPK13	S303	P308L	308	Missense	distal	5	no	55.917	55.837	EPSD;PhosphoSitePlus	GDSC	38.013	Down-regulation
CMGC_MAPK_p38_MAPK13_ST	Q00613	HSF1	O15264	MAPK13	S303	R296H	296	Missense	distal	-7	no	55.917	53.372	EPSD;PhosphoSitePlus	GDSC;CCLE	38.013	Down-regulation
CMGC_MAPK_p38_MAPK13_ST	Q00613	HSF1	O15264	MAPK13	S307	P308L	308	Missense	proximal	1	no	58.266	45.834	PhosphoSitePlus;EPSD	GDSC	38.013	Down-regulation
CMGC_MAPK_p38_MAPK13_ST	Q00613	HSF1	O15264	MAPK13	S307	E312A	312	Missense	distal	5	no	58.266	58.215	PhosphoSitePlus;EPSD	GDSC	38.013	Down-regulation
CMGC_MAPK_p38_MAPK13_ST	Q00613	HSF1	O15264	MAPK13	S314	P308L	308	Missense	distal	-6	no	48.129	47.797	EPSD	GDSC	38.013	Down-regulation
CMGC_MAPK_p38_MAPK13_ST	Q00613	HSF1	O15264	MAPK13	S314	E312A	312	Missense	proximal	-2	no	48.129	49.050	EPSD	GDSC	38.013	Up-regulation
CMGC_MAPK_p38_MAPK13_ST	Q00613	HSF1	O15264	MAPK13	S344	V345I	345	Missense	proximal	1	no	44.833	11.936	EPSD	GDSC	38.013	Loss
CMGC_MAPK_p38_MAPK13_ST	Q00613	HSF1	O15264	MAPK13	S363	R360Q	360	Missense	distal	-3	no	46.018	45.909	EPSD	GDSC	38.013	Down-regulation
CMGC_MAPK_p38_MAPK13_ST	Q00613	HSF1	O15264	MAPK13	S363	R360W	360	Missense	distal	-3	no	46.018	44.383	EPSD	GDSC;CCLE	38.013	Down-regulation
CMGC_MAPK_p38_MAPK13_ST	Q00613	HSF1	O15264	MAPK13	S419	S419R	419	Missense	central	0	yes	52.329	0.000	EPSD	GDSC	38.013	Loss
CMGC_MAPK_p38_MAPK13_ST	Q00613	HSF1	O15264	MAPK13	S419	S421W	421	Missense	proximal	2	no	52.329	49.876	EPSD	GDSC	38.013	Down-regulation
CMGC_MAPK_p38_MAPK13_ST	Q00613	HSF1	O15264	MAPK13	S419	V422L	422	Missense	distal	3	no	52.329	52.147	EPSD	GDSC;CCLE	38.013	Down-regulation
CMGC_MAPK_p38_MAPK13_ST	Q00613	HSF1	O15264	MAPK13	S458	S458I	458	Missense	central	0	yes	41.379	0.000	EPSD	GDSC;CCLE	38.013	Loss
CMGC_MAPK_p38_MAPK13_ST	P16949	STMN1	O15264	MAPK13	S31	P36T	36	Missense	distal	5	no	41.372	41.689	EPSD	GDSC;CCLE	38.013	Up-regulation
CMGC_MAPK_p38_MAPK13_ST	P16949	STMN1	O15264	MAPK13	S38	P36T	36	Missense	proximal	-2	no	52.410	52.147	EPSD;PhosphoSitePlus	GDSC;CCLE	38.013	Down-regulation
CMGC_MAPK_p38_MAPK13_ST	Q13501	SQSTM1	O15264	MAPK13	S170	L166I	166	Missense	distal	-4	no	44.023	43.312	EPSD	GDSC;CCLE	38.013	Down-regulation
CMGC_MAPK_p38_MAPK13_ST	Q13501	SQSTM1	O15264	MAPK13	S207	G214R	214	Missense	distal	7	no	46.813	47.826	EPSD	GDSC	38.013	Up-regulation
CMGC_MAPK_p38_MAPK13_ST	Q13501	SQSTM1	O15264	MAPK13	S249	V255L	255	Missense	distal	6	no	47.618	47.382	EPSD	GDSC	38.013	Down-regulation
CMGC_MAPK_p38_MAPK13_ST	Q13501	SQSTM1	O15264	MAPK13	T269	T269A	269	Missense	central	0	yes	54.468	0.000	PhosphoSitePlus;EPSD	GDSC;CCLE	38.013	Loss
CMGC_MAPK_p38_MAPK13_ST	Q13501	SQSTM1	O15264	MAPK13	T269	E274K	274	Missense	distal	5	no	54.468	54.737	PhosphoSitePlus;EPSD	GDSC;CCLE	38.013	Up-regulation
CMGC_MAPK_p38_MAPK13_ST	Q13501	SQSTM1	O15264	MAPK13	S272	T269A	269	Missense	distal	-3	no	54.137	52.845	EPSD;PhosphoSitePlus	GDSC;CCLE	38.013	Down-regulation
CMGC_MAPK_p38_MAPK13_ST	Q13501	SQSTM1	O15264	MAPK13	S272	E274K	274	Missense	proximal	2	no	54.137	55.207	EPSD;PhosphoSitePlus	GDSC;CCLE	38.013	Up-regulation
CMGC_MAPK_p38_MAPK13_ST	Q13501	SQSTM1	O15264	MAPK13	S355	L356P	356	Missense	proximal	1	no	40.187	52.620	EPSD	GDSC;CCLE	38.013	Up-regulation
CMGC_MAPK_p38_MAPK13_ST	Q13501	SQSTM1	O15264	MAPK13	S355	Q354*	354	Missense	proximal	-1	no	40.187	39.538	EPSD	GDSC	38.013	Down-regulation
CMGC_MAPK_p38_MAPK13_ST	P30281	CCND3	O15264	MAPK13	S133	P134S	134	Missense	proximal	1	no	43.271	17.720	EPSD	GDSC	38.013	Loss
STE_STE20_NinaC_MYO3A_ST	Q8NEV4	MYO3A	Q8NEV4	MYO3A	T178	T184A	184	Missense	distal	6	no	9.069	8.899	EPSD;PhosphoSitePlus	GDSC;CCLE	3.030	Down-regulation
STE_STE20_NinaC_MYO3A_ST	Q8NEV4	MYO3A	Q8NEV4	MYO3A	T184	T184A	184	Missense	central	0	yes	8.742	0.000	EPSD;PhosphoSitePlus	GDSC;CCLE	3.030	Loss
STE_STE20_NinaC_MYO3A_ST	Q8NEV4	MYO3A	Q8NEV4	MYO3A	T908	A915V	915	Missense	distal	7	no	8.285	8.286	EPSD;PhosphoSitePlus	GDSC;CCLE	3.030	Up-regulation
STE_STE20_NinaC_MYO3A_ST	Q8NEV4	MYO3A	Q8NEV4	MYO3A	T919	A915V	915	Missense	distal	-4	no	9.799	9.823	PhosphoSitePlus;EPSD	GDSC;CCLE	3.030	Up-regulation
TK_Src_SrcA_FYN_Y	Q12879	GRIN2A	P06241	FYN	Y1118	K1124T	1124	Missense	distal	6	no	3.737	3.763	PhosphoSitePlus;EPSD	GDSC;CCLE	3.469	Up-regulation
TK_Src_SrcA_FYN_Y	Q12879	GRIN2A	P06241	FYN	Y1118	E1123D	1123	Missense	distal	5	no	3.737	3.577	PhosphoSitePlus;EPSD	GDSC;CCLE	3.469	Down-regulation
TK_Src_SrcA_FYN_Y	Q12879	GRIN2A	P06241	FYN	Y1267	A1261T	1261	Missense	distal	-6	no	7.932	8.498	EPSD;PhosphoSitePlus	GDSC;CCLE	3.469	Up-regulation
TK_Src_SrcA_FYN_Y	Q12879	GRIN2A	P06241	FYN	Y1292	S1291F	1291	Missense	proximal	-1	no	5.278	5.525	EPSD	GDSC;CCLE	3.469	Up-regulation
TK_Src_SrcA_FYN_Y	Q12879	GRIN2A	P06241	FYN	Y1292	R1285M	1285	Missense	distal	-7	no	5.278	4.778	EPSD	GDSC;CCLE	3.469	Down-regulation
TK_Src_SrcA_FYN_Y	P30419	NMT1	P06241	FYN	Y327	E331*	331	Missense	distal	4	no	4.071	3.905	EPSD	GDSC	3.469	Down-regulation
TK_Src_SrcA_FYN_Y	P30419	NMT1	P06241	FYN	Y327	R322C	322	Missense	distal	-5	no	4.071	3.508	EPSD	GDSC;CCLE	3.469	Down-regulation
TK_Src_SrcA_FYN_Y	P06127	CD5	P06241	FYN	Y453	Y453*	453	Missense	central	0	yes	6.493	0.000	PhosphoSitePlus;EPSD	GDSC	3.469	Loss
TK_Src_SrcA_FYN_Y	P06127	CD5	P06241	FYN	Y453	Q455H	455	Missense	proximal	2	no	6.493	6.320	PhosphoSitePlus;EPSD	GDSC	3.469	Down-regulation
TK_Src_SrcA_FYN_Y	O15117	FYB1	P06241	FYN	Y387	T380S	380	Missense	distal	-7	no	3.667	3.384	EPSD	GDSC	3.469	Loss
TK_Src_SrcA_FYN_Y	O15117	FYB1	P06241	FYN	Y559	R556W	556	Missense	distal	-3	no	4.671	1.650	EPSD;PhosphoSitePlus	GDSC	3.469	Loss
TK_Src_SrcA_FYN_Y	O15117	FYB1	P06241	FYN	Y559	T564K	564	Missense	distal	5	no	4.671	5.213	EPSD;PhosphoSitePlus	GDSC	3.469	Up-regulation
TK_Src_SrcA_FYN_Y	O15117	FYB1	P06241	FYN	Y625	G627V	627	Missense	proximal	2	no	10.080	9.883	EPSD;PhosphoSitePlus	GDSC	3.469	Down-regulation
TK_Src_SrcA_FYN_Y	O15117	FYB1	P06241	FYN	Y625	E630D	630	Missense	distal	5	no	10.080	9.920	EPSD;PhosphoSitePlus	GDSC	3.469	Down-regulation
TK_Src_SrcA_FYN_Y	O15117	FYB1	P06241	FYN	Y651	T656M	656	Missense	distal	5	no	5.028	5.057	PhosphoSitePlus;EPSD	GDSC	3.469	Up-regulation
TK_Src_SrcA_FYN_Y	O15117	FYB1	P06241	FYN	Y651	T656N	656	Missense	distal	5	no	5.028	5.367	PhosphoSitePlus;EPSD	GDSC	3.469	Up-regulation
TK_Src_SrcA_FYN_Y	O15117	FYB1	P06241	FYN	Y709	R706K	706	Missense	distal	-3	no	3.396	4.023	EPSD	GDSC	3.469	Gain
TK_Src_SrcA_FYN_Y	P16885	PLCG2	P06241	FYN	Y1048	P1050Q	1050	Missense	proximal	2	no	6.165	6.074	EPSD	GDSC;CCLE	3.469	Down-regulation
TK_Src_SrcA_FYN_Y	O75051	PLXNA2	P06241	FYN	Y1605	T1602P	1602	Missense	distal	-3	no	5.922	4.660	PhosphoSitePlus;EPSD	GDSC	3.469	Down-regulation
TK_Src_SrcA_FYN_Y	Q03135	CAV1	P06241	FYN	Y25	N23S	23	Missense	proximal	-2	no	3.942	4.044	EPSD	GDSC	3.469	Up-regulation
TK_Src_SrcA_FYN_Y	P52757	CHN2	P06241	FYN	Y55	G57E	57	Missense	proximal	2	no	3.943	4.758	EPSD	GDSC;CCLE	3.469	Up-regulation
TK_Src_SrcA_FYN_Y	P11274	BCR	P06241	FYN	Y177	F176L	176	Missense	proximal	-1	no	7.039	8.159	PhosphoSitePlus	GDSC;CCLE	3.469	Up-regulation
TK_Src_SrcA_FYN_Y	P11274	BCR	P06241	FYN	Y455	I456T	456	Missense	proximal	1	no	5.834	6.401	EPSD	GDSC	3.469	Up-regulation
TK_Src_SrcA_FYN_Y	Q9NWQ8	PAG1	P06241	FYN	Y181	V184M	184	Missense	distal	3	no	6.193	5.709	EPSD	GDSC;CCLE	3.469	Down-regulation
TK_Src_SrcA_FYN_Y	Q9NWQ8	PAG1	P06241	FYN	Y317	A315S	315	Missense	proximal	-2	no	5.123	4.880	PhosphoSitePlus	GDSC;CCLE	3.469	Down-regulation
TK_Src_SrcA_FYN_Y	Q9NWQ8	PAG1	P06241	FYN	Y341	V336I	336	Missense	distal	-5	no	5.654	4.767	EPSD	GDSC;CCLE	3.469	Down-regulation
TK_Src_SrcA_FYN_Y	Q86WV1	SKAP1	P06241	FYN	Y232	G237S	237	Missense	distal	5	no	7.822	7.905	PhosphoSitePlus;EPSD	GDSC;CCLE	3.469	Up-regulation
TK_Src_SrcA_FYN_Y	Q86WV1	SKAP1	P06241	FYN	Y271	V273I	273	Missense	proximal	2	no	7.181	7.034	EPSD	GDSC;CCLE	3.469	Down-regulation
TK_Src_SrcA_FYN_Y	P14923	JUP	P06241	FYN	Y550	V554A	554	Missense	distal	4	no	3.818	3.868	EPSD;PhosphoSitePlus	GDSC;CCLE	3.469	Up-regulation
TK_Src_SrcA_FYN_Y	Q9UIW2	PLXNA1	P06241	FYN	Y1097	L1095R	1095	Missense	proximal	-2	no	4.910	4.767	EPSD	GDSC	3.469	Down-regulation
TK_Src_SrcA_FYN_Y	Q9UIW2	PLXNA1	P06241	FYN	Y1608	A1607V	1607	Missense	proximal	-1	no	4.852	7.528	EPSD;PhosphoSitePlus	GDSC	3.469	Up-regulation
TK_Src_SrcA_FYN_Y	P11137	MAP2	P06241	FYN	Y50	R51T	51	Missense	proximal	1	no	6.379	7.099	EPSD;PhosphoSitePlus	GDSC;CCLE	3.469	Up-regulation
TK_Src_SrcA_FYN_Y	P11137	MAP2	P06241	FYN	Y67	H61Q	61	Missense	distal	-6	no	5.132	5.204	PhosphoSitePlus;EPSD	GDSC;CCLE	3.469	Up-regulation
TK_Src_SrcA_FYN_Y	P11137	MAP2	P06241	FYN	Y637	G636W	636	Missense	proximal	-1	no	5.182	3.332	EPSD	GDSC;CCLE	3.469	Loss
TK_Src_SrcA_FYN_Y	P11137	MAP2	P06241	FYN	Y637	Q633P	633	Missense	distal	-4	no	5.182	3.931	EPSD	GDSC;CCLE	3.469	Down-regulation
TK_Src_SrcA_FYN_Y	O43490	PROM1	P06241	FYN	Y214	E210K	210	Missense	distal	-4	no	4.698	3.928	EPSD	GDSC;CCLE	3.469	Down-regulation
TK_Src_SrcA_FYN_Y	O43490	PROM1	P06241	FYN	Y214	Q211R	211	Missense	distal	-3	no	4.698	4.195	EPSD	GDSC	3.469	Down-regulation
TK_Src_SrcA_FYN_Y	O43490	PROM1	P06241	FYN	Y828	S824L	824	Missense	distal	-4	no	7.475	7.095	EPSD;PhosphoSitePlus	GDSC;CCLE	3.469	Down-regulation
TK_Src_SrcA_FYN_Y	P04626	ERBB2	P06241	FYN	Y1005	S1007*	1007	Missense	proximal	2	no	3.867	4.073	EPSD	GDSC	3.469	Up-regulation
TK_Src_SrcA_FYN_Y	P04626	ERBB2	P06241	FYN	Y1127	S1122T	1122	Missense	distal	-5	no	3.428	4.296	EPSD	GDSC	3.469	Gain
TK_Src_SrcA_FYN_Y	Q14247	CTTN	P06241	FYN	Y310	V312G	312	Missense	proximal	2	no	3.754	3.951	EPSD	GDSC	3.469	Up-regulation
TK_Src_SrcA_FYN_Y	Q14247	CTTN	P06241	FYN	Y486	E490K	490	Missense	distal	4	no	4.455	4.679	PhosphoSitePlus;EPSD	GDSC;CCLE	3.469	Up-regulation
TK_Src_SrcA_FYN_Y	O75886	STAM2	P06241	FYN	Y192	S190F	190	Missense	proximal	-2	no	4.574	4.123	EPSD	GDSC;CCLE	3.469	Down-regulation
TK_Src_SrcA_FYN_Y	O75886	STAM2	P06241	FYN	Y192	S194T	194	Missense	proximal	2	no	4.574	5.449	EPSD	GDSC;CCLE	3.469	Up-regulation
TK_Src_SrcA_FYN_Y	O75886	STAM2	P06241	FYN	Y371	Y371C	371	Missense	central	0	yes	8.745	0.000	PhosphoSitePlus;EPSD	GDSC;CCLE	3.469	Loss
TK_Src_SrcA_FYN_Y	O75886	STAM2	P06241	FYN	Y374	Y371C	371	Missense	distal	-3	no	4.897	1.818	EPSD;PhosphoSitePlus	GDSC;CCLE	3.469	Loss
TK_Src_SrcA_FYN_Y	P06241	FYN	P06241	FYN	Y185	G183V	183	Missense	proximal	-2	no	6.198	5.481	EPSD;PhosphoSitePlus	GDSC	3.469	Down-regulation
TK_Src_SrcA_FYN_Y	P06241	FYN	P06241	FYN	Y213	Y213H	213	Missense	central	0	yes	8.730	0.000	EPSD;PhosphoSitePlus	GDSC;CCLE	3.469	Loss
TK_Src_SrcA_FYN_Y	Q13291	SLAMF1	P06241	FYN	Y281	P287T	287	Missense	distal	6	no	4.588	4.552	PhosphoSitePlus;EPSD	GDSC;CCLE	3.469	Down-regulation
TK_Src_SrcA_FYN_Y	Q16539	MAPK14	P06241	FYN	Y140	I146T	146	Missense	distal	6	no	3.750	3.201	EPSD	GDSC;CCLE	3.469	Loss
TK_Src_SrcA_FYN_Y	Q8TDQ1	CD300LF	P06241	FYN	Y263	D258N	258	Missense	distal	-5	no	3.519	3.136	PhosphoSitePlus;EPSD	GDSC;CCLE	3.469	Loss
TK_Src_SrcA_FYN_Y	P22681	CBL	P06241	FYN	Y700	Y700C	700	Missense	central	0	yes	6.283	0.000	PhosphoSitePlus;EPSD	GDSC;CCLE	3.469	Loss
TK_Src_SrcA_FYN_Y	P22681	CBL	P06241	FYN	Y774	D772E	772	Missense	proximal	-2	no	6.078	6.370	EPSD;PhosphoSitePlus	GDSC	3.469	Up-regulation
TK_Src_SrcA_FYN_Y	Q12913	PTPRJ	P06241	FYN	Y1268	I1270F	1270	Missense	proximal	2	no	6.974	6.936	EPSD	GDSC;CCLE	3.469	Down-regulation
TK_Src_SrcA_FYN_Y	Q96LC7	SIGLEC10	P06241	FYN	Y597	I594M	594	Missense	distal	-3	no	4.679	6.190	EPSD	GDSC;CCLE	3.469	Up-regulation
TK_Src_SrcA_FYN_Y	Q96LC7	SIGLEC10	P06241	FYN	Y667	L670F	670	Missense	distal	3	no	5.227	5.096	PhosphoSitePlus	GDSC;CCLE	3.469	Down-regulation
TK_Src_SrcA_FYN_Y	Q96LC7	SIGLEC10	P06241	FYN	Y667	H666D	666	Missense	proximal	-1	no	5.227	4.383	PhosphoSitePlus	GDSC	3.469	Down-regulation
TK_Src_SrcA_FYN_Y	P49023	PXN	P06241	FYN	Y88	S83F	83	Missense	distal	-5	no	4.882	3.630	EPSD	GDSC	3.469	Down-regulation
TK_Src_SrcA_FYN_Y	P49023	PXN	P06241	FYN	Y88	V87E	87	Missense	proximal	-1	no	4.882	3.304	EPSD	GDSC	3.469	Loss
TK_Src_SrcA_FYN_Y	P49023	PXN	P06241	FYN	Y181	S188R	188	Missense	distal	7	no	4.438	4.457	EPSD	GDSC	3.469	Up-regulation
TK_Src_SrcA_FYN_Y	P37840	SNCA	P06241	FYN	Y125	M127I	127	Missense	proximal	2	no	5.616	5.510	PhosphoSitePlus	GDSC	3.469	Down-regulation
TK_Src_SrcA_FYN_Y	P37840	SNCA	P06241	FYN	Y125	E130G	130	Missense	distal	5	no	5.616	5.377	PhosphoSitePlus	GDSC	3.469	Down-regulation
TK_Src_SrcA_FYN_Y	P37840	SNCA	P06241	FYN	Y136	E130G	130	Missense	distal	-6	no	3.961	3.713	EPSD	GDSC	3.469	Down-regulation
TK_Src_SrcA_FYN_Y	O14522	PTPRT	P06241	FYN	Y918	R917P	917	Missense	proximal	-1	no	4.062	6.718	EPSD	GDSC;CCLE	3.469	Up-regulation
TK_Src_SrcA_FYN_Y	O14522	PTPRT	P06241	FYN	Y1008	V1007F	1007	Missense	proximal	-1	no	7.020	4.206	EPSD	GDSC	3.469	Down-regulation
TK_Src_SrcA_FYN_Y	O14522	PTPRT	P06241	FYN	Y1008	P1002L	1002	Missense	distal	-6	no	7.020	7.216	EPSD	GDSC;CCLE	3.469	Up-regulation
TK_Src_SrcA_FYN_Y	P40763	STAT3	P06241	FYN	Y446	D453N	453	Missense	distal	7	no	4.534	4.552	EPSD	GDSC;CCLE	3.469	Up-regulation
TK_Src_SrcA_FYN_Y	P40763	STAT3	P06241	FYN	Y705	C712Y	712	Missense	distal	7	no	6.980	7.025	PhosphoSitePlus	GDSC;CCLE	3.469	Up-regulation
TK_Src_SrcA_FYN_Y	P12318	FCGR2A	P06241	FYN	Y281	L274F	274	Missense	distal	-7	no	4.017	3.005	EPSD	GDSC	3.469	Loss
TK_Src_SrcA_FYN_Y	P12318	FCGR2A	P06241	FYN	Y304	D300N	300	Missense	distal	-4	no	6.199	4.920	EPSD	GDSC;CCLE	3.469	Down-regulation
TK_Src_SrcA_FYN_Y	P35637	FUS	P06241	FYN	Y468	H463L	463	Missense	distal	-5	no	5.597	5.492	EPSD	GDSC;CCLE	3.469	Down-regulation
TK_Src_SrcA_FYN_Y	Q06124	PTPN11	P06241	FYN	Y179	I172T	172	Missense	distal	-7	no	2.464	3.954	EPSD	GDSC;CCLE	3.469	Gain
TK_Src_SrcA_FYN_Y	Q06124	PTPN11	P06241	FYN	Y584	V583M	583	Missense	proximal	-1	no	4.453	3.017	EPSD	GDSC;CCLE	3.469	Loss
TK_Src_SrcA_FYN_Y	Q9NQC3	RTN4	P06241	FYN	Y694	D700A	700	Missense	distal	6	no	4.853	4.628	PhosphoSitePlus	GDSC;CCLE	3.469	Down-regulation
TK_Src_SrcA_FYN_Y	Q9NQC3	RTN4	P06241	FYN	Y694	E691K	691	Missense	distal	-3	no	4.853	4.068	PhosphoSitePlus	GDSC;CCLE	3.469	Down-regulation
TK_Src_SrcA_FYN_Y	Q15762	CD226	P06241	FYN	Y249	T250S	250	Missense	proximal	1	no	3.241	3.527	EPSD	GDSC;CCLE	3.469	Gain
TK_Src_SrcA_FYN_Y	P10636	MAPT	P06241	FYN	Y18	T17M	17	Missense	proximal	-1	no	7.108	7.489	PhosphoSitePlus	GDSC	3.469	Up-regulation
Other_TTK_TTK_ST	Q9Y5T5	USP16	P33981	TTK	S17	D14N	14	Missense	distal	-3	no	17.545	19.759	EPSD	GDSC;CCLE	18.469	Gain
Other_TTK_TTK_ST	P33981	TTK	P33981	TTK	T33	S37R	37	Missense	distal	4	no	23.444	22.502	EPSD;PhosphoSitePlus	GDSC;CCLE	18.469	Down-regulation
Other_TTK_TTK_ST	P33981	TTK	P33981	TTK	T33	K40N	40	Missense	distal	7	no	23.444	23.164	EPSD;PhosphoSitePlus	GDSC;CCLE	18.469	Down-regulation
Other_TTK_TTK_ST	P33981	TTK	P33981	TTK	S37	S37R	37	Missense	central	0	yes	26.216	0.000	EPSD;PhosphoSitePlus	GDSC;CCLE	18.469	Loss
Other_TTK_TTK_ST	P33981	TTK	P33981	TTK	S37	K40N	40	Missense	distal	3	no	26.216	25.880	EPSD;PhosphoSitePlus	GDSC;CCLE	18.469	Down-regulation
Other_TTK_TTK_ST	P33981	TTK	P33981	TTK	S80	V77A	77	Missense	distal	-3	no	24.126	23.998	EPSD;PhosphoSitePlus	GDSC;CCLE	18.469	Down-regulation
Other_TTK_TTK_ST	P33981	TTK	P33981	TTK	T360	L356V	356	Missense	distal	-4	no	20.869	20.927	EPSD;PhosphoSitePlus	GDSC	18.469	Up-regulation
Other_TTK_TTK_ST	P33981	TTK	P33981	TTK	S362	L356V	356	Missense	distal	-6	no	20.350	20.506	EPSD;PhosphoSitePlus	GDSC	18.469	Up-regulation
Other_TTK_TTK_ST	P33981	TTK	P33981	TTK	S363	L356V	356	Missense	distal	-7	no	22.150	24.604	EPSD;PhosphoSitePlus	GDSC	18.469	Up-regulation
Other_TTK_TTK_ST	P33981	TTK	P33981	TTK	S382	S389F	389	Missense	distal	7	no	19.034	17.996	EPSD	GDSC;CCLE	18.469	Loss
Other_TTK_TTK_ST	P33981	TTK	P33981	TTK	S436	P438S	438	Missense	proximal	2	no	22.439	22.087	EPSD;PhosphoSitePlus	GDSC;CCLE	18.469	Down-regulation
Other_TTK_TTK_ST	P33981	TTK	P33981	TTK	S742	Q736R	736	Missense	distal	-6	no	21.676	21.896	EPSD;PhosphoSitePlus	GDSC;CCLE	18.469	Up-regulation
Other_TTK_TTK_ST	Q53HL2	CDCA8	P33981	TTK	T152	R151I	151	Missense	proximal	-1	no	17.175	19.487	EPSD	GDSC;CCLE	18.469	Gain
Other_TTK_TTK_ST	Q53HL2	CDCA8	P33981	TTK	T169	V174M	174	Missense	distal	5	no	26.238	27.747	EPSD;PhosphoSitePlus	GDSC;CCLE	18.469	Up-regulation
Other_TTK_TTK_ST	Q53HL2	CDCA8	P33981	TTK	S238	R240*	240	Missense	proximal	2	no	24.657	23.567	EPSD;PhosphoSitePlus	GDSC	18.469	Down-regulation
Other_TTK_TTK_ST	P54132	BLM	P33981	TTK	S42	K40E	40	Missense	proximal	-2	no	19.623	19.879	EPSD	GDSC	18.469	Up-regulation
Other_TTK_TTK_ST	P54132	BLM	P33981	TTK	S43	K40E	40	Missense	distal	-3	no	19.360	19.852	EPSD	GDSC	18.469	Up-regulation
Other_TTK_TTK_ST	P54132	BLM	P33981	TTK	S144	T150A	150	Missense	distal	6	no	23.538	23.436	EPSD;PhosphoSitePlus	GDSC;CCLE	18.469	Down-regulation
Other_TTK_TTK_ST	P54132	BLM	P33981	TTK	S316	K323R	323	Missense	distal	7	no	19.672	20.552	EPSD	GDSC	18.469	Up-regulation
Other_TTK_TTK_ST	P54132	BLM	P33981	TTK	S328	K323R	323	Missense	distal	-5	no	20.257	18.971	EPSD	GDSC	18.469	Down-regulation
Other_TTK_TTK_ST	P54132	BLM	P33981	TTK	S503	S499F	499	Missense	distal	-4	no	19.605	19.563	EPSD	GDSC;CCLE	18.469	Down-regulation
Other_TTK_TTK_ST	P54132	BLM	P33981	TTK	S823	P822T	822	Missense	proximal	-1	no	16.511	20.329	EPSD	GDSC;CCLE	18.469	Gain
Other_TTK_TTK_ST	P54132	BLM	P33981	TTK	T903	D906N	906	Missense	distal	3	no	19.109	19.318	EPSD	GDSC;CCLE	18.469	Up-regulation
Other_TTK_TTK_ST	P54132	BLM	P33981	TTK	S1196	A1203V	1203	Missense	distal	7	no	18.832	18.298	EPSD	GDSC;CCLE	18.469	Loss
Other_TTK_TTK_ST	P54132	BLM	P33981	TTK	S1374	S1368A	1368	Missense	distal	-6	no	19.292	19.156	EPSD	GDSC	18.469	Down-regulation
Other_TTK_TTK_ST	P00519	ABL1	P33981	TTK	S919	P918S	918	Missense	proximal	-1	no	18.968	21.595	EPSD	GDSC	18.469	Up-regulation
Other_TTK_TTK_ST	P38646	HSPA9	P33981	TTK	T62	C66*	66	Missense	distal	4	no	19.274	18.543	PhosphoSitePlus;EPSD	GDSC	18.469	Down-regulation
Other_TTK_TTK_ST	P38646	HSPA9	P33981	TTK	S65	C66*	66	Missense	proximal	1	no	22.920	22.966	EPSD;PhosphoSitePlus	GDSC	18.469	Up-regulation
Other_TTK_TTK_ST	P38646	HSPA9	P33981	TTK	T177	M174I	174	Missense	distal	-3	no	18.852	20.587	EPSD	GDSC;CCLE	18.469	Up-regulation
Other_TTK_TTK_ST	P38646	HSPA9	P33981	TTK	S644	F648L	648	Missense	distal	4	no	18.429	19.943	EPSD	GDSC;CCLE	18.469	Gain
Other_TTK_TTK_ST	O60566	BUB1B	P33981	TTK	T474	E476*	476	Missense	proximal	2	no	18.988	16.672	EPSD	GDSC	18.469	Loss
Other_TTK_TTK_ST	O60566	BUB1B	P33981	TTK	S543	S543I	543	Missense	central	0	yes	23.191	0.000	EPSD;PhosphoSitePlus	GDSC	18.469	Loss
Other_TTK_TTK_ST	O60566	BUB1B	P33981	TTK	S543	P545S	545	Missense	proximal	2	no	23.191	22.839	EPSD;PhosphoSitePlus	GDSC;CCLE	18.469	Down-regulation
Other_TTK_TTK_ST	O60566	BUB1B	P33981	TTK	S689	S691L	691	Missense	proximal	2	no	18.401	19.351	EPSD	GDSC;CCLE	18.469	Gain
Other_TTK_TTK_ST	Q9Y6D9	MAD1L1	P33981	TTK	S62	R59H	59	Missense	distal	-3	no	22.273	21.054	EPSD;PhosphoSitePlus	GDSC	18.469	Down-regulation
Other_TTK_TTK_ST	Q9Y6D9	MAD1L1	P33981	TTK	S185	R182G	182	Missense	distal	-3	no	19.003	17.770	EPSD	GDSC	18.469	Loss
Other_TTK_TTK_ST	Q9Y6D9	MAD1L1	P33981	TTK	S185	L183R	183	Missense	proximal	-2	no	19.003	18.616	EPSD	GDSC;CCLE	18.469	Down-regulation
Other_TTK_TTK_ST	Q96PE2	ARHGEF17	P33981	TTK	S507	A510T	510	Missense	distal	3	no	18.927	16.801	EPSD	GDSC;CCLE	18.469	Loss
Other_TTK_TTK_ST	Q96PE2	ARHGEF17	P33981	TTK	S507	D503V	503	Missense	distal	-4	no	18.927	18.960	EPSD	GDSC;CCLE	18.469	Up-regulation
Other_TTK_TTK_ST	Q96PE2	ARHGEF17	P33981	TTK	S568	L571F	571	Missense	distal	3	no	19.219	13.854	EPSD	GDSC;CCLE	18.469	Loss
Other_TTK_TTK_ST	Q96PE2	ARHGEF17	P33981	TTK	T702	T699P	699	Missense	distal	-3	no	20.131	16.937	EPSD	GDSC;CCLE	18.469	Loss
Other_TTK_TTK_ST	Q96PE2	ARHGEF17	P33981	TTK	T702	L706I	706	Missense	distal	4	no	20.131	20.235	EPSD	GDSC;CCLE	18.469	Up-regulation
Other_TTK_TTK_ST	Q96PE2	ARHGEF17	P33981	TTK	S827	K824E	824	Missense	distal	-3	no	19.563	20.055	EPSD	GDSC;CCLE	18.469	Up-regulation
Other_TTK_TTK_ST	Q96PE2	ARHGEF17	P33981	TTK	S829	K824E	824	Missense	distal	-5	no	18.048	19.237	EPSD	GDSC;CCLE	18.469	Gain
Other_TTK_TTK_ST	Q96PE2	ARHGEF17	P33981	TTK	T944	S946C	946	Missense	proximal	2	no	23.911	23.636	EPSD;PhosphoSitePlus	GDSC;CCLE	18.469	Down-regulation
Other_TTK_TTK_ST	Q9Y6R1	SLC4A4	P33981	TTK	S77	S77N	77	Missense	central	0	yes	19.968	0.000	EPSD	GDSC;CCLE	18.469	Loss
Other_TTK_TTK_ST	O96017	CHEK2	P33981	TTK	T68	S73F	73	Missense	distal	5	no	22.982	24.097	PhosphoSitePlus	GDSC;CCLE	18.469	Up-regulation
Other_TTK_TTK_ST	Q6IBW4	NCAPH2	P33981	TTK	S95	Q93R	93	Missense	proximal	-2	no	20.265	19.366	EPSD	GDSC;CCLE	18.469	Down-regulation
Other_TTK_TTK_ST	Q6IBW4	NCAPH2	P33981	TTK	S96	Q93R	93	Missense	distal	-3	no	22.429	21.181	EPSD	GDSC;CCLE	18.469	Down-regulation
Other_TTK_TTK_ST	Q6IBW4	NCAPH2	P33981	TTK	T403	Q408*	408	Missense	distal	5	no	23.422	26.914	EPSD	GDSC	18.469	Up-regulation
AGC_PKC_PKCa_PRKCA_ST	P35367	HRH1	P17252	PRKCA	S94	S94L	94	Missense	central	0	yes	16.736	0.000	EPSD	GDSC;CCLE	16.704	Loss
AGC_PKC_PKCa_PRKCA_ST	P35367	HRH1	P17252	PRKCA	T478	K477N	477	Missense	proximal	-1	no	17.273	16.671	PhosphoSitePlus;EPSD	GDSC;CCLE	16.704	Loss
AGC_PKC_PKCa_PRKCA_ST	P29474	NOS3	P17252	PRKCA	S114	G116S	116	Missense	proximal	2	no	16.159	16.784	EPSD	GDSC	16.704	Gain
AGC_PKC_PKCa_PRKCA_ST	P29474	NOS3	P17252	PRKCA	S600	N598I	598	Missense	proximal	-2	no	18.159	17.767	EPSD	GDSC;CCLE	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	P29474	NOS3	P17252	PRKCA	S625	R627Q	627	Missense	proximal	2	no	21.855	18.021	EPSD	GDSC;CCLE	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	P29474	NOS3	P17252	PRKCA	S625	R628Q	628	Missense	distal	3	no	21.855	19.402	EPSD	GDSC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	P29474	NOS3	P17252	PRKCA	S633	R627Q	627	Missense	distal	-6	no	18.170	18.027	EPSD	GDSC;CCLE	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	P29474	NOS3	P17252	PRKCA	S633	R628Q	628	Missense	distal	-5	no	18.170	18.018	EPSD	GDSC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	P29474	NOS3	P17252	PRKCA	S725	R721G	721	Missense	distal	-4	no	17.751	17.649	EPSD	GDSC;CCLE	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	P09758	TACSTD2	P17252	PRKCA	S142	S142N	142	Missense	central	0	yes	18.250	0.000	EPSD	GDSC;CCLE	16.704	Loss
AGC_PKC_PKCa_PRKCA_ST	P09758	TACSTD2	P17252	PRKCA	S303	R300Q	300	Missense	distal	-3	no	21.793	18.935	PhosphoSitePlus	GDSC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	Q9BR39	JPH2	P17252	PRKCA	S235	R236H	236	Missense	proximal	1	no	18.470	17.657	EPSD	GDSC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	Q9BR39	JPH2	P17252	PRKCA	S238	R236H	236	Missense	proximal	-2	no	17.579	13.026	EPSD	GDSC	16.704	Loss
AGC_PKC_PKCa_PRKCA_ST	Q9BR39	JPH2	P17252	PRKCA	S241	R236H	236	Missense	distal	-5	no	20.964	20.609	EPSD	GDSC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	Q9BR39	JPH2	P17252	PRKCA	S359	R363H	363	Missense	distal	4	no	19.136	18.854	EPSD	GDSC;CCLE	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	Q9BR39	JPH2	P17252	PRKCA	S359	Q356*	356	Missense	distal	-3	no	19.136	16.449	EPSD	GDSC	16.704	Loss
AGC_PKC_PKCa_PRKCA_ST	P29966	MARCKS	P17252	PRKCA	S170	K176T	176	Missense	distal	6	no	21.726	21.618	EPSD;PhosphoSitePlus	GDSC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	P11387	TOP1	P17252	PRKCA	S74	H81R	81	Missense	distal	7	no	17.158	17.229	EPSD	GDSC;CCLE	16.704	Up-regulation
AGC_PKC_PKCa_PRKCA_ST	P11387	TOP1	P17252	PRKCA	S423	M428T	428	Missense	distal	5	no	17.718	17.415	EPSD	GDSC;CCLE	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	P11387	TOP1	P17252	PRKCA	S534	D528E	528	Missense	distal	-6	no	20.451	20.534	EPSD	GDSC;CCLE	16.704	Up-regulation
AGC_PKC_PKCa_PRKCA_ST	Q15080	NCF4	P17252	PRKCA	S11	D12E	12	Missense	proximal	1	no	18.416	18.448	EPSD	GDSC;CCLE	16.704	Up-regulation
AGC_PKC_PKCa_PRKCA_ST	Q15080	NCF4	P17252	PRKCA	S11	P17L	17	Missense	distal	6	no	18.416	18.372	EPSD	GDSC;CCLE	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	Q15080	NCF4	P17252	PRKCA	T154	R151C	151	Missense	distal	-3	no	20.732	17.992	EPSD;PhosphoSitePlus	GDSC;CCLE	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	Q15080	NCF4	P17252	PRKCA	T154	R149W	149	Missense	distal	-5	no	20.732	20.418	EPSD;PhosphoSitePlus	GDSC;CCLE	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	Q15080	NCF4	P17252	PRKCA	S315	R311H	311	Missense	distal	-4	no	17.857	17.282	PhosphoSitePlus;EPSD	GDSC;CCLE	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	P16144	ITGB4	P17252	PRKCA	S99	D93Y	93	Missense	distal	-6	no	18.291	18.322	EPSD	GDSC	16.704	Up-regulation
AGC_PKC_PKCa_PRKCA_ST	P16144	ITGB4	P17252	PRKCA	S99	Q104E	104	Missense	distal	5	no	18.291	18.030	EPSD	GDSC;CCLE	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	P16144	ITGB4	P17252	PRKCA	S102	Q104E	104	Missense	proximal	2	no	18.480	16.613	EPSD	GDSC;CCLE	16.704	Loss
AGC_PKC_PKCa_PRKCA_ST	P16144	ITGB4	P17252	PRKCA	S397	E404*	404	Missense	distal	7	no	17.492	17.461	EPSD	GDSC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	P16144	ITGB4	P17252	PRKCA	S397	T393A	393	Missense	distal	-4	no	17.492	18.241	EPSD	GDSC	16.704	Up-regulation
AGC_PKC_PKCa_PRKCA_ST	P16144	ITGB4	P17252	PRKCA	S1140	A1137V	1137	Missense	distal	-3	no	18.713	19.472	EPSD	GDSC;CCLE	16.704	Up-regulation
AGC_PKC_PKCa_PRKCA_ST	P16144	ITGB4	P17252	PRKCA	S1547	C1553R	1553	Missense	distal	6	no	17.233	17.472	EPSD	GDSC;CCLE	16.704	Up-regulation
AGC_PKC_PKCa_PRKCA_ST	P16144	ITGB4	P17252	PRKCA	S1747	R1748C	1748	Missense	proximal	1	no	17.243	14.407	EPSD	GDSC;CCLE	16.704	Loss
AGC_PKC_PKCa_PRKCA_ST	Q8NER1	TRPV1	P17252	PRKCA	S186	N192D	192	Missense	distal	6	no	18.027	18.112	EPSD	GDSC;CCLE	16.704	Up-regulation
AGC_PKC_PKCa_PRKCA_ST	Q8NER1	TRPV1	P17252	PRKCA	S186	A193S	193	Missense	distal	7	no	18.027	18.029	EPSD	GDSC;CCLE	16.704	Up-regulation
AGC_PKC_PKCa_PRKCA_ST	Q8NER1	TRPV1	P17252	PRKCA	S502	V508M	508	Missense	distal	6	no	23.256	23.344	EPSD;PhosphoSitePlus	GDSC	16.704	Up-regulation
AGC_PKC_PKCa_PRKCA_ST	Q8NER1	TRPV1	P17252	PRKCA	S801	E799D	799	Missense	proximal	-2	no	20.241	20.949	PhosphoSitePlus;EPSD	GDSC;CCLE	16.704	Up-regulation
AGC_PKC_PKCa_PRKCA_ST	Q8NER1	TRPV1	P17252	PRKCA	S801	R803*	803	Missense	proximal	2	no	20.241	10.995	PhosphoSitePlus;EPSD	GDSC	16.704	Loss
AGC_PKC_PKCa_PRKCA_ST	Q8NER1	TRPV1	P17252	PRKCA	S821	L815M	815	Missense	distal	-6	no	16.924	16.986	EPSD	GDSC;CCLE	16.704	Up-regulation
AGC_PKC_PKCa_PRKCA_ST	P08684	CYP3A4	P17252	PRKCA	T103	P107T	107	Missense	distal	4	no	16.840	16.609	EPSD;PhosphoSitePlus	GDSC	16.704	Loss
AGC_PKC_PKCa_PRKCA_ST	P08684	CYP3A4	P17252	PRKCA	S259	R260H	260	Missense	proximal	1	no	17.083	16.270	EPSD;PhosphoSitePlus	GDSC;CCLE	16.704	Loss
AGC_PKC_PKCa_PRKCA_ST	P08684	CYP3A4	P17252	PRKCA	S420	K424R	424	Missense	distal	4	no	20.156	19.985	EPSD;PhosphoSitePlus	GDSC;CCLE	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	P08684	CYP3A4	P17252	PRKCA	S464	C468Y	468	Missense	distal	4	no	17.368	18.126	EPSD	GDSC;CCLE	16.704	Up-regulation
AGC_PKC_PKCa_PRKCA_ST	P18031	PTPN1	P17252	PRKCA	S378	V375M	375	Missense	distal	-3	no	21.090	21.807	PhosphoSitePlus	GDSC	16.704	Up-regulation
AGC_PKC_PKCa_PRKCA_ST	P18031	PTPN1	P17252	PRKCA	S378	A382D	382	Missense	distal	4	no	21.090	20.721	PhosphoSitePlus	GDSC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	P10636	MAPT	P17252	PRKCA	S171	D177V	177	Missense	distal	6	no	19.508	19.437	EPSD	GDSC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	P10636	MAPT	P17252	PRKCA	T470	A475V	475	Missense	distal	5	no	16.965	16.581	EPSD	GDSC;CCLE	16.704	Loss
AGC_PKC_PKCa_PRKCA_ST	P10636	MAPT	P17252	PRKCA	S637	V635I	635	Missense	proximal	-2	no	18.000	17.254	EPSD	GDSC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	O75689	ADAP1	P17252	PRKCA	S204	I208M	208	Missense	distal	4	no	16.922	18.417	EPSD	GDSC;CCLE	16.704	Up-regulation
AGC_PKC_PKCa_PRKCA_ST	P31645	SLC6A4	P17252	PRKCA	S13	A14V	14	Missense	proximal	1	no	18.065	18.218	EPSD	GDSC;CCLE	16.704	Up-regulation
AGC_PKC_PKCa_PRKCA_ST	P31645	SLC6A4	P17252	PRKCA	S277	V281M	281	Missense	distal	4	no	17.966	19.338	EPSD;PhosphoSitePlus	GDSC;CCLE	16.704	Up-regulation
AGC_PKC_PKCa_PRKCA_ST	P05107	ITGB2	P17252	PRKCA	S496	K499N	499	Missense	distal	3	no	17.597	16.649	EPSD	GDSC;CCLE	16.704	Loss
AGC_PKC_PKCa_PRKCA_ST	O60941	DTNB	P17252	PRKCA	T11	E14K	14	Missense	distal	3	no	19.127	19.743	EPSD	GDSC;CCLE	16.704	Up-regulation
AGC_PKC_PKCa_PRKCA_ST	O60941	DTNB	P17252	PRKCA	S250	R247*	247	Missense	distal	-3	no	21.054	15.510	EPSD	GDSC	16.704	Loss
AGC_PKC_PKCa_PRKCA_ST	Q9UKG1	APPL1	P17252	PRKCA	S410	H408Q	408	Missense	proximal	-2	no	21.037	23.831	EPSD	GDSC;CCLE	16.704	Up-regulation
AGC_PKC_PKCa_PRKCA_ST	Q9UKG1	APPL1	P17252	PRKCA	S636	R634M	634	Missense	proximal	-2	no	22.058	20.077	EPSD	GDSC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	Q9UKG1	APPL1	P17252	PRKCA	S636	E630Q	630	Missense	distal	-6	no	22.058	21.990	EPSD	GDSC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	Q9UKG1	APPL1	P17252	PRKCA	S636	A629G	629	Missense	distal	-7	no	22.058	22.052	EPSD	GDSC;CCLE	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	Q9UKG1	APPL1	P17252	PRKCA	S636	I642M	642	Missense	distal	6	no	22.058	22.091	EPSD	GDSC	16.704	Up-regulation
AGC_PKC_PKCa_PRKCA_ST	P04626	ERBB2	P17252	PRKCA	S1050	R1048C	1048	Missense	proximal	-2	no	16.820	15.121	EPSD	GDSC;CCLE	16.704	Loss
AGC_PKC_PKCa_PRKCA_ST	P04626	ERBB2	P17252	PRKCA	S1051	R1048C	1048	Missense	distal	-3	no	21.659	18.920	EPSD	GDSC;CCLE	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	P04626	ERBB2	P17252	PRKCA	S1151	P1149S	1149	Missense	proximal	-2	no	19.955	19.695	EPSD	GDSC;CCLE	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	P08253	MMP2	P17252	PRKCA	S160	E166K	166	Missense	distal	6	no	16.872	16.966	EPSD;PhosphoSitePlus	GDSC	16.704	Up-regulation
AGC_PKC_PKCa_PRKCA_ST	P21730	C5AR1	P17252	PRKCA	S314	L315H	315	Missense	proximal	1	no	17.842	17.376	PhosphoSitePlus;EPSD	GDSC;CCLE	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	Q9H3Q1	CDC42EP4	P17252	PRKCA	S10	R17H	17	Missense	distal	7	no	17.706	17.635	EPSD	GDSC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	Q9H3Q1	CDC42EP4	P17252	PRKCA	S11	R17H	17	Missense	distal	6	no	17.583	17.506	EPSD	GDSC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	Q9H3Q1	CDC42EP4	P17252	PRKCA	S14	R17H	17	Missense	distal	3	no	25.078	24.366	EPSD	GDSC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	Q9H3Q1	CDC42EP4	P17252	PRKCA	S18	R17H	17	Missense	proximal	-1	no	19.773	19.450	PhosphoSitePlus;EPSD	GDSC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	Q9H3Q1	CDC42EP4	P17252	PRKCA	S77	F83L	83	Missense	distal	6	no	18.331	18.362	EPSD	GDSC;CCLE	16.704	Up-regulation
AGC_PKC_PKCa_PRKCA_ST	Q9H3Q1	CDC42EP4	P17252	PRKCA	S80	F83L	83	Missense	distal	3	no	20.408	20.074	EPSD;PhosphoSitePlus	GDSC;CCLE	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	Q9H3Q1	CDC42EP4	P17252	PRKCA	S89	F83L	83	Missense	distal	-6	no	18.491	18.511	EPSD	GDSC;CCLE	16.704	Up-regulation
AGC_PKC_PKCa_PRKCA_ST	Q9H3Q1	CDC42EP4	P17252	PRKCA	S91	E98*	98	Missense	distal	7	no	17.474	17.443	EPSD	GDSC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	Q9H3Q1	CDC42EP4	P17252	PRKCA	S105	E98*	98	Missense	distal	-7	no	19.370	19.369	EPSD	GDSC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	Q07954	LRP1	P17252	PRKCA	S514	C519Y	519	Missense	distal	5	no	17.600	18.217	EPSD	GDSC;CCLE	16.704	Up-regulation
AGC_PKC_PKCa_PRKCA_ST	Q07954	LRP1	P17252	PRKCA	S2563	N2562T	2562	Missense	proximal	-1	no	19.367	19.146	EPSD	GDSC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	Q07954	LRP1	P17252	PRKCA	S4071	T4077R	4077	Missense	distal	6	no	18.278	18.398	EPSD	GDSC	16.704	Up-regulation
AGC_PKC_PKCa_PRKCA_ST	Q07954	LRP1	P17252	PRKCA	T4460	G4462R	4462	Missense	proximal	2	no	16.438	21.683	EPSD;PhosphoSitePlus	GDSC;CCLE	16.704	Gain
AGC_PKC_PKCa_PRKCA_ST	P52565	ARHGDIA	P17252	PRKCA	S96	L90P	90	Missense	distal	-6	no	20.335	20.369	EPSD;PhosphoSitePlus	GDSC;CCLE	16.704	Up-regulation
AGC_PKC_PKCa_PRKCA_ST	P52565	ARHGDIA	P17252	PRKCA	S96	D93G	93	Missense	distal	-3	no	20.335	22.115	EPSD;PhosphoSitePlus	GDSC;CCLE	16.704	Up-regulation
AGC_PKC_PKCa_PRKCA_ST	P52565	ARHGDIA	P17252	PRKCA	T132	G125D	125	Missense	distal	-7	no	17.698	17.697	EPSD	GDSC;CCLE	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	P52565	ARHGDIA	P17252	PRKCA	S176	R172Q	172	Missense	distal	-4	no	17.490	17.113	EPSD	GDSC;CCLE	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	P53004	BLVRA	P17252	PRKCA	S21	R18G	18	Missense	distal	-3	no	24.825	21.563	EPSD	GDSC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	P08183	ABCB1	P17252	PRKCA	S590	I585K	585	Missense	distal	-5	no	16.664	17.222	EPSD	GDSC;CCLE	16.704	Gain
AGC_PKC_PKCa_PRKCA_ST	P08183	ABCB1	P17252	PRKCA	T591	S590P	590	Missense	proximal	-1	no	19.388	19.089	EPSD	GDSC;CCLE	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	P08183	ABCB1	P17252	PRKCA	T591	I585K	585	Missense	distal	-6	no	19.388	19.552	EPSD	GDSC;CCLE	16.704	Up-regulation
AGC_PKC_PKCa_PRKCA_ST	P08183	ABCB1	P17252	PRKCA	S667	G674*	674	Missense	distal	7	no	24.429	24.327	EPSD;PhosphoSitePlus	GDSC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	P08183	ABCB1	P17252	PRKCA	S671	G674*	674	Missense	distal	3	no	22.872	20.438	EPSD;PhosphoSitePlus	GDSC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	P08183	ABCB1	P17252	PRKCA	S675	G674*	674	Missense	proximal	-1	no	18.840	17.238	EPSD	GDSC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	O14745	SLC9A3R1	P17252	PRKCA	T156	R151W	151	Missense	distal	-5	no	17.300	16.986	EPSD	GDSC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	O14745	SLC9A3R1	P17252	PRKCA	S308	D301V	301	Missense	distal	-7	no	17.418	17.414	EPSD	GDSC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	O14745	SLC9A3R1	P17252	PRKCA	S339	S340N	340	Missense	proximal	1	no	19.714	19.761	EPSD;PhosphoSitePlus	GDSC;CCLE	16.704	Up-regulation
AGC_PKC_PKCa_PRKCA_ST	O14745	SLC9A3R1	P17252	PRKCA	S340	S340N	340	Missense	central	0	yes	21.773	0.000	PhosphoSitePlus;EPSD	GDSC;CCLE	16.704	Loss
AGC_PKC_PKCa_PRKCA_ST	Q96RI1	NR1H4	P17252	PRKCA	S31	P34H	34	Missense	distal	3	no	18.330	19.148	EPSD	GDSC;CCLE	16.704	Up-regulation
AGC_PKC_PKCa_PRKCA_ST	Q96RI1	NR1H4	P17252	PRKCA	S31	M30V	30	Missense	proximal	-1	no	18.330	16.208	EPSD	GDSC;CCLE	16.704	Loss
AGC_PKC_PKCa_PRKCA_ST	P78536	ADAM17	P17252	PRKCA	T761	Q763H	763	Missense	proximal	2	no	17.286	16.097	EPSD	GDSC;CCLE	16.704	Loss
AGC_PKC_PKCa_PRKCA_ST	P78536	ADAM17	P17252	PRKCA	T761	Q757R	757	Missense	distal	-4	no	17.286	17.664	EPSD	GDSC;CCLE	16.704	Up-regulation
AGC_PKC_PKCa_PRKCA_ST	O95243	MBD4	P17252	PRKCA	S253	T246N	246	Missense	distal	-7	no	16.828	16.826	EPSD	GDSC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	O95243	MBD4	P17252	PRKCA	S253	G249A	249	Missense	distal	-4	no	16.828	16.823	EPSD	GDSC;CCLE	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	O95243	MBD4	P17252	PRKCA	S380	E381Q	381	Missense	proximal	1	no	15.353	16.803	EPSD	GDSC;CCLE	16.704	Gain
AGC_PKC_PKCa_PRKCA_ST	P48048	KCNJ1	P17252	PRKCA	T191	R188H	188	Missense	distal	-3	no	18.331	14.475	EPSD	GDSC	16.704	Loss
AGC_PKC_PKCa_PRKCA_ST	P55042	RRAD	P17252	PRKCA	S257	Q250R	250	Missense	distal	-7	no	19.878	19.886	PhosphoSitePlus;EPSD	GDSC;CCLE	16.704	Up-regulation
AGC_PKC_PKCa_PRKCA_ST	P04004	VTN	P17252	PRKCA	S225	T219I	219	Missense	distal	-6	no	17.604	17.633	EPSD	GDSC;CCLE	16.704	Up-regulation
AGC_PKC_PKCa_PRKCA_ST	P04004	VTN	P17252	PRKCA	S381	R387G	387	Missense	distal	6	no	21.671	21.522	EPSD;PhosphoSitePlus	GDSC;CCLE	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	P04004	VTN	P17252	PRKCA	S386	R387G	387	Missense	proximal	1	no	18.744	17.790	EPSD;PhosphoSitePlus	GDSC;CCLE	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	P04004	VTN	P17252	PRKCA	S393	R395W	395	Missense	proximal	2	no	19.847	14.407	PhosphoSitePlus;EPSD	GDSC;CCLE	16.704	Loss
AGC_PKC_PKCa_PRKCA_ST	P04004	VTN	P17252	PRKCA	S393	R387G	387	Missense	distal	-6	no	19.847	19.740	PhosphoSitePlus;EPSD	GDSC;CCLE	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	P04004	VTN	P17252	PRKCA	S397	L404F	404	Missense	distal	7	no	18.183	18.116	EPSD;PhosphoSitePlus	GDSC;CCLE	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	P04004	VTN	P17252	PRKCA	S397	R395W	395	Missense	proximal	-2	no	18.183	16.185	EPSD;PhosphoSitePlus	GDSC;CCLE	16.704	Loss
AGC_PKC_PKCa_PRKCA_ST	P36542	ATP5F1C	P17252	PRKCA	S98	V96M	96	Missense	proximal	-2	no	18.305	19.166	EPSD	GDSC	16.704	Up-regulation
AGC_PKC_PKCa_PRKCA_ST	P23528	CFL1	P17252	PRKCA	S113	L111R	111	Missense	proximal	-2	no	14.443	17.131	EPSD	GDSC;CCLE	16.704	Gain
AGC_PKC_PKCa_PRKCA_ST	Q96KS0	EGLN2	P17252	PRKCA	S252	R251G	251	Missense	proximal	-1	no	17.169	17.030	EPSD	GDSC;CCLE	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	Q07869	PPARA	P17252	PRKCA	S230	I228V	228	Missense	proximal	-2	no	17.877	18.623	PhosphoSitePlus;EPSD	GDSC;CCLE	16.704	Up-regulation
AGC_PKC_PKCa_PRKCA_ST	P04637	TP53	P17252	PRKCA	S99	K101*	101	Missense	proximal	2	no	17.589	8.765	EPSD	GDSC	16.704	Loss
AGC_PKC_PKCa_PRKCA_ST	P04637	TP53	P17252	PRKCA	S99	Q100*	100	Missense	proximal	1	no	17.589	16.835	EPSD	GDSC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	P04637	TP53	P17252	PRKCA	S99	S94*	94	Missense	distal	-5	no	17.589	17.395	EPSD	GDSC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	P04637	TP53	P17252	PRKCA	T211	R213*	213	Missense	proximal	2	no	18.834	9.588	EPSD	GDSC	16.704	Loss
AGC_PKC_PKCa_PRKCA_ST	P04637	TP53	P17252	PRKCA	T211	R209*	209	Missense	proximal	-2	no	18.834	14.051	EPSD	GDSC	16.704	Loss
AGC_PKC_PKCa_PRKCA_ST	P04637	TP53	P17252	PRKCA	S269	E271*	271	Missense	proximal	2	no	17.682	14.137	EPSD	GDSC	16.704	Loss
AGC_PKC_PKCa_PRKCA_ST	P04637	TP53	P17252	PRKCA	T304	R306*	306	Missense	proximal	2	no	16.706	7.460	EPSD	GDSC	16.704	Loss
AGC_PKC_PKCa_PRKCA_ST	P04637	TP53	P17252	PRKCA	T304	E298*	298	Missense	distal	-6	no	16.706	16.533	EPSD	GDSC	16.704	Loss
AGC_PKC_PKCa_PRKCA_ST	P60880	SNAP25	P17252	PRKCA	T138	R142*	142	Missense	distal	4	no	16.985	15.787	EPSD;PhosphoSitePlus	GDSC	16.704	Loss
AGC_PKC_PKCa_PRKCA_ST	Q8NF50	DOCK8	P17252	PRKCA	S6	A11T	11	Missense	distal	5	no	17.409	17.131	EPSD	GDSC;CCLE	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	Q15311	RALBP1	P17252	PRKCA	S116	K123N	123	Missense	distal	7	no	20.343	20.223	EPSD	GDSC;CCLE	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	Q15311	RALBP1	P17252	PRKCA	S118	K123N	123	Missense	distal	5	no	19.915	19.409	EPSD;PhosphoSitePlus	GDSC;CCLE	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	Q15311	RALBP1	P17252	PRKCA	S509	R504C	504	Missense	distal	-5	no	16.726	16.050	EPSD;PhosphoSitePlus	GDSC;CCLE	16.704	Loss
AGC_PKC_PKCa_PRKCA_ST	Q12809	KCNH2	P17252	PRKCA	S354	P347S	347	Missense	distal	-7	no	17.261	17.264	EPSD	GDSC	16.704	Up-regulation
AGC_PKC_PKCa_PRKCA_ST	Q12809	KCNH2	P17252	PRKCA	S354	E357K	357	Missense	distal	3	no	17.261	17.877	EPSD	GDSC;CCLE	16.704	Up-regulation
AGC_PKC_PKCa_PRKCA_ST	Q12809	KCNH2	P17252	PRKCA	S890	R894G	894	Missense	distal	4	no	27.532	26.928	PhosphoSitePlus	GDSC;CCLE	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	Q12809	KCNH2	P17252	PRKCA	T895	R894G	894	Missense	proximal	-1	no	21.854	21.714	EPSD	GDSC;CCLE	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	P15336	ATF2	P17252	PRKCA	S62	V63A	63	Missense	proximal	1	no	17.530	17.377	EPSD	GDSC;CCLE	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	P15336	ATF2	P17252	PRKCA	S340	R342H	342	Missense	proximal	2	no	19.248	14.225	EPSD	GDSC;CCLE	16.704	Loss
AGC_PKC_PKCa_PRKCA_ST	P15336	ATF2	P17252	PRKCA	S427	D433H	433	Missense	distal	6	no	17.317	17.329	EPSD	GDSC;CCLE	16.704	Up-regulation
AGC_PKC_PKCa_PRKCA_ST	P15336	ATF2	P17252	PRKCA	S427	G428S	428	Missense	proximal	1	no	17.317	17.096	EPSD	GDSC;CCLE	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	Q9NRY4	ARHGAP35	P17252	PRKCA	S589	Q586K	586	Missense	distal	-3	no	16.949	17.780	EPSD	GDSC;CCLE	16.704	Up-regulation
AGC_PKC_PKCa_PRKCA_ST	Q9NRY4	ARHGAP35	P17252	PRKCA	S839	H841R	841	Missense	proximal	2	no	14.402	19.426	EPSD	GDSC;CCLE	16.704	Gain
AGC_PKC_PKCa_PRKCA_ST	Q9NRY4	ARHGAP35	P17252	PRKCA	S845	H841R	841	Missense	distal	-4	no	19.980	20.555	EPSD	GDSC;CCLE	16.704	Up-regulation
AGC_PKC_PKCa_PRKCA_ST	Q9NRY4	ARHGAP35	P17252	PRKCA	S849	H853Y	853	Missense	distal	4	no	17.000	16.639	EPSD	GDSC	16.704	Loss
AGC_PKC_PKCa_PRKCA_ST	Q9NRY4	ARHGAP35	P17252	PRKCA	S849	H853L	853	Missense	distal	4	no	17.000	16.244	EPSD	GDSC	16.704	Loss
AGC_PKC_PKCa_PRKCA_ST	Q9NRY4	ARHGAP35	P17252	PRKCA	S849	I856N	856	Missense	distal	7	no	17.000	17.130	EPSD	GDSC;CCLE	16.704	Up-regulation
AGC_PKC_PKCa_PRKCA_ST	Q9NRY4	ARHGAP35	P17252	PRKCA	S860	A865S	865	Missense	distal	5	no	16.881	16.778	EPSD	GDSC;CCLE	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	Q9NRY4	ARHGAP35	P17252	PRKCA	S860	H853Y	853	Missense	distal	-7	no	16.881	16.883	EPSD	GDSC	16.704	Up-regulation
AGC_PKC_PKCa_PRKCA_ST	Q9NRY4	ARHGAP35	P17252	PRKCA	S860	H853L	853	Missense	distal	-7	no	16.881	16.878	EPSD	GDSC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	Q9NRY4	ARHGAP35	P17252	PRKCA	S860	S866T	866	Missense	distal	6	no	16.881	16.833	EPSD	GDSC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	Q9NRY4	ARHGAP35	P17252	PRKCA	S860	I856N	856	Missense	distal	-4	no	16.881	16.993	EPSD	GDSC;CCLE	16.704	Up-regulation
AGC_PKC_PKCa_PRKCA_ST	Q9NRY4	ARHGAP35	P17252	PRKCA	S1221	T1226S	1226	Missense	distal	5	no	20.552	20.728	EPSD;PhosphoSitePlus	GDSC;CCLE	16.704	Up-regulation
AGC_PKC_PKCa_PRKCA_ST	O60716	CTNND1	P17252	PRKCA	T61	R68W	68	Missense	distal	7	no	17.197	17.017	EPSD	GDSC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	O60716	CTNND1	P17252	PRKCA	S320	M324I	324	Missense	distal	4	no	18.883	17.388	EPSD	GDSC;CCLE	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	O60716	CTNND1	P17252	PRKCA	S484	W477*	477	Missense	distal	-7	no	20.140	20.144	EPSD	GDSC	16.704	Up-regulation
AGC_PKC_PKCa_PRKCA_ST	O60716	CTNND1	P17252	PRKCA	S879	K881N	881	Missense	proximal	2	no	18.797	13.848	PhosphoSitePlus	GDSC;CCLE	16.704	Loss
AGC_PKC_PKCa_PRKCA_ST	O60716	CTNND1	P17252	PRKCA	S879	Q877*	877	Missense	proximal	-2	no	18.797	15.774	PhosphoSitePlus	GDSC	16.704	Loss
AGC_PKC_PKCa_PRKCA_ST	O60716	CTNND1	P17252	PRKCA	S891	N892D	892	Missense	proximal	1	no	17.011	16.539	EPSD	GDSC	16.704	Loss
AGC_PKC_PKCa_PRKCA_ST	Q9NQA5	TRPV5	P17252	PRKCA	S142	R146I	146	Missense	distal	4	no	19.851	18.161	EPSD	GDSC;CCLE	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	Q9NQA5	TRPV5	P17252	PRKCA	S142	R140S	140	Missense	proximal	-2	no	19.851	16.549	EPSD	GDSC;CCLE	16.704	Loss
AGC_PKC_PKCa_PRKCA_ST	Q9NQA5	TRPV5	P17252	PRKCA	S654	V650E	650	Missense	distal	-4	no	19.496	19.465	EPSD;PhosphoSitePlus	GDSC;CCLE	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	P43629	KIR3DL1	P17252	PRKCA	S102	H99R	99	Missense	distal	-3	no	14.599	18.455	EPSD	GDSC	16.704	Gain
AGC_PKC_PKCa_PRKCA_ST	P43629	KIR3DL1	P17252	PRKCA	S296	G289R	289	Missense	distal	-7	no	20.275	20.284	EPSD	GDSC	16.704	Up-regulation
AGC_PKC_PKCa_PRKCA_ST	P43629	KIR3DL1	P17252	PRKCA	S296	G295S	295	Missense	proximal	-1	no	20.275	20.027	EPSD	GDSC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	P43629	KIR3DL1	P17252	PRKCA	S415	P422S	422	Missense	distal	7	no	19.172	19.136	PhosphoSitePlus	GDSC;CCLE	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	O75955	FLOT1	P17252	PRKCA	S19	P20S	20	Missense	proximal	1	no	16.978	16.578	EPSD	GDSC	16.704	Loss
AGC_PKC_PKCa_PRKCA_ST	Q14315	FLNC	P17252	PRKCA	T423	V426M	426	Missense	distal	3	no	17.935	18.521	EPSD	GDSC;CCLE	16.704	Up-regulation
AGC_PKC_PKCa_PRKCA_ST	Q14315	FLNC	P17252	PRKCA	T909	R916L	916	Missense	distal	7	no	18.124	18.080	EPSD	GDSC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	Q14315	FLNC	P17252	PRKCA	S1007	C1013Y	1013	Missense	distal	6	no	18.149	18.336	EPSD	GDSC;CCLE	16.704	Up-regulation
AGC_PKC_PKCa_PRKCA_ST	Q14315	FLNC	P17252	PRKCA	S2016	S2016R	2016	Missense	central	0	yes	18.009	0.000	EPSD	GDSC;CCLE	16.704	Loss
AGC_PKC_PKCa_PRKCA_ST	Q14315	FLNC	P17252	PRKCA	T2125	G2121*	2121	Missense	distal	-4	no	17.356	16.663	EPSD	GDSC	16.704	Loss
AGC_PKC_PKCa_PRKCA_ST	Q14315	FLNC	P17252	PRKCA	S2137	R2142S	2142	Missense	distal	5	no	19.341	19.200	EPSD	GDSC;CCLE	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	Q14315	FLNC	P17252	PRKCA	S2233	R2230H	2230	Missense	distal	-3	no	17.184	13.328	EPSD	GDSC	16.704	Loss
AGC_PKC_PKCa_PRKCA_ST	Q14315	FLNC	P17252	PRKCA	T2412	D2406N	2406	Missense	distal	-6	no	18.158	18.185	EPSD	GDSC;CCLE	16.704	Up-regulation
AGC_PKC_PKCa_PRKCA_ST	Q14315	FLNC	P17252	PRKCA	S2619	R2621Q	2621	Missense	proximal	2	no	20.752	16.918	EPSD	GDSC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	Q14315	FLNC	P17252	PRKCA	S2623	R2621Q	2621	Missense	proximal	-2	no	18.749	16.990	EPSD;PhosphoSitePlus	GDSC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	Q14315	FLNC	P17252	PRKCA	S2624	R2621Q	2621	Missense	distal	-3	no	17.410	14.552	PhosphoSitePlus;EPSD	GDSC	16.704	Loss
AGC_PKC_PKCa_PRKCA_ST	P56537	EIF6	P17252	PRKCA	S6	E8Q	8	Missense	proximal	2	no	16.815	18.681	EPSD	GDSC	16.704	Up-regulation
AGC_PKC_PKCa_PRKCA_ST	P56537	EIF6	P17252	PRKCA	S6	A5S	5	Missense	proximal	-1	no	16.815	17.374	EPSD	GDSC	16.704	Up-regulation
AGC_PKC_PKCa_PRKCA_ST	Q06124	PTPN11	P17252	PRKCA	S264	E258D	258	Missense	distal	-6	no	19.360	19.277	EPSD	GDSC;CCLE	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	Q06124	PTPN11	P17252	PRKCA	S580	V583M	583	Missense	distal	3	no	17.475	18.061	EPSD	GDSC;CCLE	16.704	Up-regulation
AGC_PKC_PKCa_PRKCA_ST	Q14432	PDE3A	P17252	PRKCA	S304	G302S	302	Missense	proximal	-2	no	17.721	17.292	EPSD	GDSC;CCLE	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	Q14432	PDE3A	P17252	PRKCA	S305	G302S	302	Missense	distal	-3	no	17.664	18.056	EPSD	GDSC;CCLE	16.704	Up-regulation
AGC_PKC_PKCa_PRKCA_ST	Q14432	PDE3A	P17252	PRKCA	S463	P457Q	457	Missense	distal	-6	no	16.813	16.775	EPSD	GDSC;CCLE	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	Q14432	PDE3A	P17252	PRKCA	S543	Q546R	546	Missense	distal	3	no	15.099	17.552	EPSD	GDSC;CCLE	16.704	Gain
AGC_PKC_PKCa_PRKCA_ST	Q14432	PDE3A	P17252	PRKCA	S543	I542M	542	Missense	proximal	-1	no	15.099	17.042	EPSD	GDSC;CCLE	16.704	Gain
AGC_PKC_PKCa_PRKCA_ST	Q14432	PDE3A	P17252	PRKCA	S593	G589C	589	Missense	distal	-4	no	17.099	15.858	EPSD	GDSC;CCLE	16.704	Loss
AGC_PKC_PKCa_PRKCA_ST	Q14432	PDE3A	P17252	PRKCA	S654	L650M	650	Missense	distal	-4	no	19.438	20.141	EPSD	GDSC	16.704	Up-regulation
AGC_PKC_PKCa_PRKCA_ST	Q14432	PDE3A	P17252	PRKCA	S1060	T1065I	1065	Missense	distal	5	no	17.940	17.922	EPSD	GDSC;CCLE	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	Q8WZ42	TTN	P17252	PRKCA	S79	K81R	81	Missense	proximal	2	no	20.202	20.623	EPSD	GDSC	16.704	Up-regulation
AGC_PKC_PKCa_PRKCA_ST	Q8WZ42	TTN	P17252	PRKCA	S112	R116T	116	Missense	distal	4	no	17.735	17.058	EPSD	GDSC;CCLE	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	Q8WZ42	TTN	P17252	PRKCA	S112	V107I	107	Missense	distal	-5	no	17.735	17.728	EPSD	GDSC;CCLE	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	Q8WZ42	TTN	P17252	PRKCA	T863	T869S	869	Missense	distal	6	no	17.979	18.027	EPSD	GDSC;CCLE	16.704	Up-regulation
AGC_PKC_PKCa_PRKCA_ST	Q8WZ42	TTN	P17252	PRKCA	S1348	S1348R	1348	Missense	central	0	yes	20.626	0.000	EPSD	GDSC;CCLE	16.704	Loss
AGC_PKC_PKCa_PRKCA_ST	Q8WZ42	TTN	P17252	PRKCA	S1348	L1342I	1342	Missense	distal	-6	no	20.626	20.594	EPSD	GDSC;CCLE	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	Q8WZ42	TTN	P17252	PRKCA	S1428	A1435E	1435	Missense	distal	7	no	19.125	19.077	EPSD	GDSC;CCLE	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	Q8WZ42	TTN	P17252	PRKCA	S1433	A1435E	1435	Missense	proximal	2	no	17.000	15.998	EPSD	GDSC;CCLE	16.704	Loss
AGC_PKC_PKCa_PRKCA_ST	Q8WZ42	TTN	P17252	PRKCA	S1540	S1539P	1539	Missense	proximal	-1	no	18.905	18.605	EPSD	GDSC;CCLE	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	Q8WZ42	TTN	P17252	PRKCA	S2316	N2309K	2309	Missense	distal	-7	no	18.161	18.166	EPSD	GDSC	16.704	Up-regulation
AGC_PKC_PKCa_PRKCA_ST	Q8WZ42	TTN	P17252	PRKCA	T2695	T2690I	2690	Missense	distal	-5	no	17.338	16.865	EPSD	GDSC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	Q8WZ42	TTN	P17252	PRKCA	T2695	E2688K	2688	Missense	distal	-7	no	17.338	17.345	EPSD	GDSC;CCLE	16.704	Up-regulation
AGC_PKC_PKCa_PRKCA_ST	Q8WZ42	TTN	P17252	PRKCA	S2763	K2767T	2767	Missense	distal	4	no	17.684	16.836	EPSD	GDSC;CCLE	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	Q8WZ42	TTN	P17252	PRKCA	S8276	S8276F	8276	Missense	central	0	yes	18.369	0.000	EPSD	GDSC	16.704	Loss
AGC_PKC_PKCa_PRKCA_ST	Q8WZ42	TTN	P17252	PRKCA	S17116	T17122A	17122	Missense	distal	6	no	19.246	19.324	EPSD	GDSC	16.704	Up-regulation
AGC_PKC_PKCa_PRKCA_ST	Q8WZ42	TTN	P17252	PRKCA	S18909	I18908M	18908	Missense	proximal	-1	no	15.086	17.029	EPSD	GDSC	16.704	Gain
AGC_PKC_PKCa_PRKCA_ST	Q8WZ42	TTN	P17252	PRKCA	S19174	P19175H	19175	Missense	proximal	1	no	17.207	17.168	EPSD	GDSC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	Q8WZ42	TTN	P17252	PRKCA	T21837	E21835K	21835	Missense	proximal	-2	no	16.917	19.416	EPSD	GDSC	16.704	Up-regulation
AGC_PKC_PKCa_PRKCA_ST	Q8WZ42	TTN	P17252	PRKCA	S21840	E21835K	21835	Missense	distal	-5	no	17.035	17.329	EPSD	GDSC	16.704	Up-regulation
AGC_PKC_PKCa_PRKCA_ST	Q8WZ42	TTN	P17252	PRKCA	S22742	T22744K	22744	Missense	proximal	2	no	14.006	18.395	EPSD	GDSC	16.704	Gain
AGC_PKC_PKCa_PRKCA_ST	Q8WZ42	TTN	P17252	PRKCA	T23118	T23119I	23119	Missense	proximal	1	no	16.353	17.689	EPSD	GDSC	16.704	Gain
AGC_PKC_PKCa_PRKCA_ST	Q8WZ42	TTN	P17252	PRKCA	S33088	R33082Q	33082	Missense	distal	-6	no	17.091	16.948	EPSD	GDSC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	Q8WZ42	TTN	P17252	PRKCA	S33251	S33247L	33247	Missense	distal	-4	no	17.482	17.051	EPSD	GDSC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	P49841	GSK3B	P17252	PRKCA	S2	T8P	8	Missense	distal	6	no	22.225	22.306	EPSD	GDSC	16.704	Up-regulation
AGC_PKC_PKCa_PRKCA_ST	P49841	GSK3B	P17252	PRKCA	T7	T8P	8	Missense	proximal	1	no	17.165	17.238	EPSD	GDSC	16.704	Up-regulation
AGC_PKC_PKCa_PRKCA_ST	P49841	GSK3B	P17252	PRKCA	S9	T8P	8	Missense	proximal	-1	no	20.161	20.239	PhosphoSitePlus	GDSC	16.704	Up-regulation
AGC_PKC_PKCa_PRKCA_ST	P49841	GSK3B	P17252	PRKCA	S13	T8P	8	Missense	distal	-5	no	17.093	17.091	EPSD	GDSC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	P49841	GSK3B	P17252	PRKCA	S21	S21L	21	Missense	central	0	yes	17.906	0.000	EPSD	GDSC;CCLE	16.704	Loss
AGC_PKC_PKCa_PRKCA_ST	P49841	GSK3B	P17252	PRKCA	S25	S21L	21	Missense	distal	-4	no	17.924	17.493	EPSD	GDSC;CCLE	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	P35579	MYH9	P17252	PRKCA	S36	K30*	30	Missense	distal	-6	no	19.356	19.115	EPSD	GDSC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	P35579	MYH9	P17252	PRKCA	S304	F302L	302	Missense	proximal	-2	no	16.096	17.381	EPSD	GDSC;CCLE	16.704	Gain
AGC_PKC_PKCa_PRKCA_ST	P35579	MYH9	P17252	PRKCA	T638	R644C	644	Missense	distal	6	no	16.837	16.597	EPSD	GDSC;CCLE	16.704	Loss
AGC_PKC_PKCa_PRKCA_ST	P35579	MYH9	P17252	PRKCA	S1122	Q1117*	1117	Missense	distal	-5	no	17.484	17.014	EPSD	GDSC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	P35579	MYH9	P17252	PRKCA	S1122	R1124H	1124	Missense	proximal	2	no	17.484	12.460	EPSD	GDSC;CCLE	16.704	Loss
AGC_PKC_PKCa_PRKCA_ST	P35579	MYH9	P17252	PRKCA	S1126	R1124H	1124	Missense	proximal	-2	no	17.515	12.961	EPSD	GDSC;CCLE	16.704	Loss
AGC_PKC_PKCa_PRKCA_ST	P35579	MYH9	P17252	PRKCA	S1340	E1346*	1346	Missense	distal	6	no	18.230	18.144	EPSD	GDSC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	P35579	MYH9	P17252	PRKCA	S1480	R1483L	1483	Missense	distal	3	no	17.106	14.868	EPSD	GDSC;CCLE	16.704	Loss
AGC_PKC_PKCa_PRKCA_ST	P35579	MYH9	P17252	PRKCA	S1480	L1479M	1479	Missense	proximal	-1	no	17.106	18.185	EPSD	GDSC;CCLE	16.704	Up-regulation
AGC_PKC_PKCa_PRKCA_ST	P35579	MYH9	P17252	PRKCA	S1606	R1612Q	1612	Missense	distal	6	no	17.030	16.907	EPSD	GDSC;CCLE	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	P35579	MYH9	P17252	PRKCA	S1677	E1672K	1672	Missense	distal	-5	no	16.840	17.134	EPSD	GDSC;CCLE	16.704	Up-regulation
AGC_PKC_PKCa_PRKCA_ST	P35579	MYH9	P17252	PRKCA	S1714	A1720S	1720	Missense	distal	6	no	17.204	17.174	EPSD	GDSC;CCLE	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	P35579	MYH9	P17252	PRKCA	S1714	S1713N	1713	Missense	proximal	-1	no	17.204	17.046	EPSD	GDSC;CCLE	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	P17812	CTPS1	P17252	PRKCA	S225	S231*	231	Missense	distal	6	no	17.845	17.724	EPSD	GDSC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	Q15717	ELAVL1	P17252	PRKCA	S202	S197L	197	Missense	distal	-5	no	17.216	17.515	EPSD	GDSC;CCLE	16.704	Up-regulation
AGC_PKC_PKCa_PRKCA_ST	Q9UQ80	PA2G4	P17252	PRKCA	S2	S2W	2	Missense	central	0	yes	17.394	0.000	EPSD	GDSC;CCLE	16.704	Loss
AGC_PKC_PKCa_PRKCA_ST	Q9UQ80	PA2G4	P17252	PRKCA	T261	S262L	262	Missense	proximal	1	no	18.343	19.169	EPSD	GDSC;CCLE	16.704	Up-regulation
AGC_PKC_PKCa_PRKCA_ST	Q9UQ80	PA2G4	P17252	PRKCA	S361	Q359*	359	Missense	proximal	-2	no	17.625	14.601	EPSD	GDSC	16.704	Loss
AGC_PKC_PKCa_PRKCA_ST	Q9UQ80	PA2G4	P17252	PRKCA	S363	Q359*	359	Missense	distal	-4	no	19.396	18.978	EPSD	GDSC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	Q9UQ80	PA2G4	P17252	PRKCA	T366	Q359*	359	Missense	distal	-7	no	22.111	22.106	EPSD;PhosphoSitePlus	GDSC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	P21359	NF1	P17252	PRKCA	S302	R304*	304	Missense	proximal	2	no	18.764	9.518	EPSD	GDSC	16.704	Loss
AGC_PKC_PKCa_PRKCA_ST	P21359	NF1	P17252	PRKCA	S657	T653I	653	Missense	distal	-4	no	18.653	18.873	EPSD	GDSC;CCLE	16.704	Up-regulation
AGC_PKC_PKCa_PRKCA_ST	P21359	NF1	P17252	PRKCA	S2181	D2184G	2184	Missense	distal	3	no	24.251	25.336	EPSD	GDSC;CCLE	16.704	Up-regulation
AGC_PKC_PKCa_PRKCA_ST	P21359	NF1	P17252	PRKCA	S2186	D2184G	2184	Missense	proximal	-2	no	17.618	18.164	EPSD	GDSC;CCLE	16.704	Up-regulation
AGC_PKC_PKCa_PRKCA_ST	P21359	NF1	P17252	PRKCA	T2540	K2535M	2535	Missense	distal	-5	no	17.266	17.112	EPSD	GDSC;CCLE	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	P30086	PEBP1	P17252	PRKCA	S60	L58H	58	Missense	proximal	-2	no	17.037	15.171	EPSD	GDSC	16.704	Loss
AGC_PKC_PKCa_PRKCA_ST	Q05193	DNM1	P17252	PRKCA	S774	R772H	772	Missense	proximal	-2	no	18.929	14.375	EPSD	GDSC;CCLE	16.704	Loss
AGC_PKC_PKCa_PRKCA_ST	Q05193	DNM1	P17252	PRKCA	S857	D863Y	863	Missense	distal	6	no	20.368	20.405	EPSD	GDSC;CCLE	16.704	Up-regulation
AGC_PKC_PKCa_PRKCA_ST	P04049	RAF1	P17252	PRKCA	S43	A42V	42	Missense	proximal	-1	no	19.600	18.696	EPSD;PhosphoSitePlus	GDSC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	P04049	RAF1	P17252	PRKCA	S43	A42T	42	Missense	proximal	-1	no	19.600	19.780	EPSD;PhosphoSitePlus	GDSC	16.704	Up-regulation
AGC_PKC_PKCa_PRKCA_ST	P04049	RAF1	P17252	PRKCA	T213	P207S	207	Missense	distal	-6	no	17.244	17.275	EPSD	GDSC;CCLE	16.704	Up-regulation
AGC_PKC_PKCa_PRKCA_ST	P04049	RAF1	P17252	PRKCA	S220	V226I	226	Missense	distal	6	no	19.272	19.327	EPSD	GDSC;CCLE	16.704	Up-regulation
AGC_PKC_PKCa_PRKCA_ST	P04049	RAF1	P17252	PRKCA	S252	Q253P	253	Missense	proximal	1	no	17.092	16.434	EPSD	GDSC	16.704	Loss
AGC_PKC_PKCa_PRKCA_ST	P04049	RAF1	P17252	PRKCA	S257	Q253P	253	Missense	distal	-4	no	18.677	18.689	EPSD	GDSC	16.704	Up-regulation
AGC_PKC_PKCa_PRKCA_ST	P04049	RAF1	P17252	PRKCA	S352	S352F	352	Missense	central	0	yes	16.787	0.000	EPSD	GDSC;CCLE	16.704	Loss
AGC_PKC_PKCa_PRKCA_ST	O94806	PRKD3	P17252	PRKCA	S9	S9*	9	Missense	central	0	yes	18.875	0.000	EPSD	GDSC	16.704	Loss
AGC_PKC_PKCa_PRKCA_ST	O94806	PRKD3	P17252	PRKCA	S13	S9*	9	Missense	distal	-4	no	17.886	17.284	EPSD	GDSC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	O94806	PRKD3	P17252	PRKCA	S247	Q244E	244	Missense	distal	-3	no	17.954	15.873	EPSD	GDSC;CCLE	16.704	Loss
AGC_PKC_PKCa_PRKCA_ST	O94806	PRKD3	P17252	PRKCA	S247	S247C	247	Missense	central	0	yes	17.954	0.000	EPSD	GDSC;CCLE	16.704	Loss
AGC_PKC_PKCa_PRKCA_ST	O94806	PRKD3	P17252	PRKCA	S252	S247C	247	Missense	distal	-5	no	19.862	19.613	EPSD	GDSC;CCLE	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	O94806	PRKD3	P17252	PRKCA	S406	K408E	408	Missense	proximal	2	no	21.892	16.612	EPSD	GDSC;CCLE	16.704	Loss
AGC_PKC_PKCa_PRKCA_ST	O94806	PRKD3	P17252	PRKCA	S406	V403I	403	Missense	distal	-3	no	21.892	21.094	EPSD	GDSC;CCLE	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	O94806	PRKD3	P17252	PRKCA	S415	K408E	408	Missense	distal	-7	no	18.899	18.891	EPSD	GDSC;CCLE	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	O94806	PRKD3	P17252	PRKCA	S470	E464K	464	Missense	distal	-6	no	19.758	19.825	EPSD	GDSC;CCLE	16.704	Up-regulation
AGC_PKC_PKCa_PRKCA_ST	O94806	PRKD3	P17252	PRKCA	S731	S735T	735	Missense	distal	4	no	20.461	20.030	PhosphoSitePlus	GDSC;CCLE	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	O94806	PRKD3	P17252	PRKCA	S822	S822N	822	Missense	central	0	yes	20.749	0.000	EPSD	GDSC;CCLE	16.704	Loss
AGC_PKC_PKCa_PRKCA_ST	P01589	IL2RA	P17252	PRKCA	S268	R264T	264	Missense	distal	-4	no	19.951	19.096	PhosphoSitePlus;EPSD	GDSC;CCLE	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	P13569	CFTR	P17252	PRKCA	T501	I507V	507	Missense	distal	6	no	18.338	18.283	EPSD	GDSC;CCLE	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	P13569	CFTR	P17252	PRKCA	T501	E504*	504	Missense	distal	3	no	18.338	16.503	EPSD	GDSC	16.704	Loss
AGC_PKC_PKCa_PRKCA_ST	P13569	CFTR	P17252	PRKCA	S686	T690A	690	Missense	distal	4	no	19.152	19.599	EPSD	GDSC;CCLE	16.704	Up-regulation
AGC_PKC_PKCa_PRKCA_ST	P13569	CFTR	P17252	PRKCA	S686	K688N	688	Missense	proximal	2	no	19.152	14.203	EPSD	GDSC;CCLE	16.704	Loss
AGC_PKC_PKCa_PRKCA_ST	P13569	CFTR	P17252	PRKCA	S686	E681V	681	Missense	distal	-5	no	19.152	18.895	EPSD	GDSC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	P13569	CFTR	P17252	PRKCA	S700	I705T	705	Missense	distal	5	no	18.593	18.611	EPSD	GDSC;CCLE	16.704	Up-regulation
AGC_PKC_PKCa_PRKCA_ST	P13569	CFTR	P17252	PRKCA	S700	E695K	695	Missense	distal	-5	no	18.593	18.887	EPSD	GDSC;CCLE	16.704	Up-regulation
AGC_PKC_PKCa_PRKCA_ST	P13569	CFTR	P17252	PRKCA	S707	I705T	705	Missense	proximal	-2	no	19.036	19.730	EPSD	GDSC;CCLE	16.704	Up-regulation
AGC_PKC_PKCa_PRKCA_ST	P13569	CFTR	P17252	PRKCA	S813	Q814L	814	Missense	proximal	1	no	18.100	17.870	EPSD;PhosphoSitePlus	GDSC;CCLE	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	P13569	CFTR	P17252	PRKCA	S1248	G1244E	1244	Missense	distal	-4	no	21.308	20.714	EPSD	GDSC;CCLE	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	P13569	CFTR	P17252	PRKCA	S1455	R1453W	1453	Missense	proximal	-2	no	17.317	15.319	EPSD	GDSC	16.704	Loss
AGC_PKC_PKCa_PRKCA_ST	P13569	CFTR	P17252	PRKCA	S1456	R1453W	1453	Missense	distal	-3	no	17.642	15.288	EPSD	GDSC	16.704	Loss
AGC_PKC_PKCa_PRKCA_ST	Q9Y624	F11R	P17252	PRKCA	S274	S275N	275	Missense	proximal	1	no	18.112	18.159	EPSD	GDSC	16.704	Up-regulation
AGC_PKC_PKCa_PRKCA_ST	Q9UBS0	RPS6KB2	P17252	PRKCA	S219	G214R	214	Missense	distal	-5	no	17.293	17.583	EPSD	GDSC;CCLE	16.704	Up-regulation
AGC_PKC_PKCa_PRKCA_ST	Q9UBS0	RPS6KB2	P17252	PRKCA	S416	R419Q	419	Missense	distal	3	no	20.048	17.595	EPSD	GDSC;CCLE	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	Q9UBS0	RPS6KB2	P17252	PRKCA	S417	R419Q	419	Missense	proximal	2	no	18.341	14.507	EPSD	GDSC;CCLE	16.704	Loss
AGC_PKC_PKCa_PRKCA_ST	Q13303	KCNAB2	P17252	PRKCA	S5	T7M	7	Missense	proximal	2	no	16.395	16.758	EPSD	GDSC;CCLE	16.704	Gain
AGC_PKC_PKCa_PRKCA_ST	Q13303	KCNAB2	P17252	PRKCA	S9	T7M	7	Missense	proximal	-2	no	16.522	17.434	EPSD	GDSC;CCLE	16.704	Gain
AGC_PKC_PKCa_PRKCA_ST	Q13303	KCNAB2	P17252	PRKCA	S14	T7M	7	Missense	distal	-7	no	20.870	20.875	EPSD	GDSC;CCLE	16.704	Up-regulation
AGC_PKC_PKCa_PRKCA_ST	Q13303	KCNAB2	P17252	PRKCA	S112	G107A	107	Missense	distal	-5	no	19.218	19.028	EPSD	GDSC;CCLE	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	P01730	CD4	P17252	PRKCA	S440	Q446K	446	Missense	distal	6	no	18.086	18.196	EPSD;PhosphoSitePlus	GDSC;CCLE	16.704	Up-regulation
AGC_PKC_PKCa_PRKCA_ST	P01730	CD4	P17252	PRKCA	S440	E441G	441	Missense	proximal	1	no	18.086	18.699	EPSD;PhosphoSitePlus	GDSC	16.704	Up-regulation
AGC_PKC_PKCa_PRKCA_ST	Q05209	PTPN12	P17252	PRKCA	S186	Q183E	183	Missense	distal	-3	no	17.667	15.587	EPSD	GDSC;CCLE	16.704	Loss
AGC_PKC_PKCa_PRKCA_ST	Q05209	PTPN12	P17252	PRKCA	S342	C343F	343	Missense	proximal	1	no	15.661	18.807	EPSD	GDSC;CCLE	16.704	Gain
AGC_PKC_PKCa_PRKCA_ST	Q05209	PTPN12	P17252	PRKCA	S435	R432*	432	Missense	distal	-3	no	17.671	12.127	EPSD;PhosphoSitePlus	GDSC	16.704	Loss
AGC_PKC_PKCa_PRKCA_ST	P21399	ACO1	P17252	PRKCA	S778	E773K	773	Missense	distal	-5	no	17.767	18.061	EPSD	GDSC	16.704	Up-regulation
AGC_PKC_PKCa_PRKCA_ST	P21731	TBXA2R	P17252	PRKCA	S145	W150*	150	Missense	distal	5	no	18.398	18.495	PhosphoSitePlus;EPSD	GDSC	16.704	Up-regulation
AGC_PKC_PKCa_PRKCA_ST	P21731	TBXA2R	P17252	PRKCA	S145	A142V	142	Missense	distal	-3	no	18.398	19.157	PhosphoSitePlus;EPSD	GDSC;CCLE	16.704	Up-regulation
AGC_PKC_PKCa_PRKCA_ST	P21731	TBXA2R	P17252	PRKCA	S324	S324N	324	Missense	central	0	yes	18.282	0.000	EPSD;PhosphoSitePlus	GDSC	16.704	Loss
AGC_PKC_PKCa_PRKCA_ST	P06213	INSR	P17252	PRKCA	S1064	N1060D	1060	Missense	distal	-4	no	17.717	17.369	PhosphoSitePlus;EPSD	GDSC;CCLE	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	Q02156	PRKCE	P17252	PRKCA	S234	D230V	230	Missense	distal	-4	no	19.631	19.837	EPSD;PhosphoSitePlus	GDSC;CCLE	16.704	Up-regulation
AGC_PKC_PKCa_PRKCA_ST	Q96PY5	FMNL2	P17252	PRKCA	S205	R199L	199	Missense	distal	-6	no	17.694	17.555	EPSD	GDSC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	Q96PY5	FMNL2	P17252	PRKCA	T450	D443N	443	Missense	distal	-7	no	16.916	16.915	EPSD	GDSC;CCLE	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	Q96PY5	FMNL2	P17252	PRKCA	S834	G829R	829	Missense	distal	-5	no	19.601	19.892	EPSD	GDSC	16.704	Up-regulation
AGC_PKC_PKCa_PRKCA_ST	Q96PY5	FMNL2	P17252	PRKCA	S835	G829R	829	Missense	distal	-6	no	19.529	19.637	EPSD	GDSC	16.704	Up-regulation
AGC_PKC_PKCa_PRKCA_ST	P35398	RORA	P17252	PRKCA	S49	S54N	54	Missense	distal	5	no	18.128	17.907	EPSD	GDSC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	Q05940	SLC18A2	P17252	PRKCA	S279	T283S	283	Missense	distal	4	no	21.202	21.633	EPSD	GDSC;CCLE	16.704	Up-regulation
AGC_PKC_PKCa_PRKCA_ST	P35612	ADD2	P17252	PRKCA	S62	P61L	61	Missense	proximal	-1	no	18.890	18.770	EPSD	GDSC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	P35612	ADD2	P17252	PRKCA	S455	P456S	456	Missense	proximal	1	no	19.179	18.779	EPSD	GDSC;CCLE	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	P35612	ADD2	P17252	PRKCA	S703	R710Q	710	Missense	distal	7	no	18.466	18.462	EPSD	GDSC;CCLE	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	P35612	ADD2	P17252	PRKCA	S713	R710Q	710	Missense	distal	-3	no	18.575	15.717	EPSD;PhosphoSitePlus	GDSC;CCLE	16.704	Loss
AGC_PKC_PKCa_PRKCA_ST	P35612	ADD2	P17252	PRKCA	S718	V724M	724	Missense	distal	6	no	19.678	19.766	EPSD	GDSC;CCLE	16.704	Up-regulation
AGC_PKC_PKCa_PRKCA_ST	Q9NRF2	SH2B1	P17252	PRKCA	S65	S65P	65	Missense	central	0	yes	16.928	0.000	EPSD	GDSC	16.704	Loss
AGC_PKC_PKCa_PRKCA_ST	Q9NRF2	SH2B1	P17252	PRKCA	S65	A62T	62	Missense	distal	-3	no	16.928	17.214	EPSD	GDSC;CCLE	16.704	Up-regulation
AGC_PKC_PKCa_PRKCA_ST	Q9NRF2	SH2B1	P17252	PRKCA	S157	V162I	162	Missense	distal	5	no	17.155	17.242	EPSD	GDSC;CCLE	16.704	Up-regulation
AGC_PKC_PKCa_PRKCA_ST	Q9NRF2	SH2B1	P17252	PRKCA	S161	V162I	162	Missense	proximal	1	no	21.126	21.837	PhosphoSitePlus;EPSD	GDSC;CCLE	16.704	Up-regulation
AGC_PKC_PKCa_PRKCA_ST	Q9NRF2	SH2B1	P17252	PRKCA	S165	V162I	162	Missense	distal	-3	no	23.313	22.515	EPSD;PhosphoSitePlus	GDSC;CCLE	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	Q9NRF2	SH2B1	P17252	PRKCA	S279	G281R	281	Missense	proximal	2	no	12.788	18.033	EPSD	GDSC;CCLE	16.704	Gain
AGC_PKC_PKCa_PRKCA_ST	Q9H1D0	TRPV6	P17252	PRKCA	S182	A187T	187	Missense	distal	5	no	19.957	19.678	EPSD	GDSC;CCLE	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	O95786	DDX58	P17252	PRKCA	S308	E304A	304	Missense	distal	-4	no	16.957	17.547	EPSD	GDSC;CCLE	16.704	Up-regulation
AGC_PKC_PKCa_PRKCA_ST	O95786	DDX58	P17252	PRKCA	S854	E857G	857	Missense	distal	3	no	16.897	17.496	EPSD	GDSC;CCLE	16.704	Up-regulation
AGC_PKC_PKCa_PRKCA_ST	P07949	RET	P17252	PRKCA	S159	T152P	152	Missense	distal	-7	no	18.041	18.040	EPSD	GDSC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	P07949	RET	P17252	PRKCA	S686	S688Y	688	Missense	proximal	2	no	16.759	16.884	EPSD	GDSC;CCLE	16.704	Up-regulation
AGC_PKC_PKCa_PRKCA_ST	P07949	RET	P17252	PRKCA	S696	P695A	695	Missense	proximal	-1	no	20.184	19.925	EPSD	GDSC;CCLE	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	P05556	ITGB1	P17252	PRKCA	S61	G57E	57	Missense	distal	-4	no	18.513	17.919	EPSD	GDSC;CCLE	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	O15519	CFLAR	P17252	PRKCA	S193	D196Y	196	Missense	distal	3	no	18.401	17.858	PhosphoSitePlus	GDSC;CCLE	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	P25098	GRK2	P17252	PRKCA	S389	K383E	383	Missense	distal	-6	no	20.141	20.074	EPSD	GDSC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	P25098	GRK2	P17252	PRKCA	S389	P390L	390	Missense	proximal	1	no	20.141	20.568	EPSD	GDSC	16.704	Up-regulation
AGC_PKC_PKCa_PRKCA_ST	P08670	VIM	P17252	PRKCA	S293	E300K	300	Missense	distal	7	no	17.032	17.178	EPSD	GDSC;CCLE	16.704	Up-regulation
AGC_PKC_PKCa_PRKCA_ST	Q04637	EIF4G1	P17252	PRKCA	T179	R183*	183	Missense	distal	4	no	17.960	16.762	EPSD	GDSC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	Q04637	EIF4G1	P17252	PRKCA	T179	K174R	174	Missense	distal	-5	no	17.960	17.973	EPSD	GDSC	16.704	Up-regulation
AGC_PKC_PKCa_PRKCA_ST	Q04637	EIF4G1	P17252	PRKCA	T179	T179P	179	Missense	central	0	yes	17.960	0.000	EPSD	GDSC;CCLE	16.704	Loss
AGC_PKC_PKCa_PRKCA_ST	Q04637	EIF4G1	P17252	PRKCA	S895	R893Q	893	Missense	proximal	-2	no	18.587	16.828	EPSD	GDSC;CCLE	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	Q04637	EIF4G1	P17252	PRKCA	S895	A891T	891	Missense	distal	-4	no	18.587	17.838	EPSD	GDSC;CCLE	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	Q04637	EIF4G1	P17252	PRKCA	S1164	R1157Q	1157	Missense	distal	-7	no	16.751	16.743	EPSD	GDSC;CCLE	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	P14598	NCF1	P17252	PRKCA	S320	Y324H	324	Missense	distal	4	no	18.045	18.407	PhosphoSitePlus;EPSD	GDSC;CCLE	16.704	Up-regulation
AGC_PKC_PKCa_PRKCA_ST	P14598	NCF1	P17252	PRKCA	S328	Y324H	324	Missense	distal	-4	no	24.594	24.406	EPSD;PhosphoSitePlus	GDSC;CCLE	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	Q86UR1	NOXA1	P17252	PRKCA	S461	A463T	463	Missense	proximal	2	no	17.072	16.960	EPSD	GDSC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	Q86UR1	NOXA1	P17252	PRKCA	S461	A463P	463	Missense	proximal	2	no	17.072	16.568	EPSD	GDSC	16.704	Loss
AGC_PKC_PKCa_PRKCA_ST	Q03721	KCNC4	P17252	PRKCA	S15	P20S	20	Missense	distal	5	no	19.374	19.214	PhosphoSitePlus;EPSD	GDSC;CCLE	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	Q03721	KCNC4	P17252	PRKCA	S577	A573G	573	Missense	distal	-4	no	17.833	17.838	EPSD	GDSC;CCLE	16.704	Up-regulation
AGC_PKC_PKCa_PRKCA_ST	Q03721	KCNC4	P17252	PRKCA	T578	A573G	573	Missense	distal	-5	no	21.447	21.637	EPSD	GDSC;CCLE	16.704	Up-regulation
AGC_PKC_PKCa_PRKCA_ST	P46940	IQGAP1	P17252	PRKCA	S86	F84L	84	Missense	proximal	-2	no	16.551	17.836	EPSD	GDSC;CCLE	16.704	Gain
AGC_PKC_PKCa_PRKCA_ST	P46940	IQGAP1	P17252	PRKCA	S91	F84L	84	Missense	distal	-7	no	18.228	18.230	EPSD	GDSC;CCLE	16.704	Up-regulation
AGC_PKC_PKCa_PRKCA_ST	P46940	IQGAP1	P17252	PRKCA	S360	D353E	353	Missense	distal	-7	no	18.760	18.756	EPSD	GDSC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	P46940	IQGAP1	P17252	PRKCA	S1227	L1232F	1232	Missense	distal	5	no	17.528	17.752	EPSD	GDSC	16.704	Up-regulation
AGC_PKC_PKCa_PRKCA_ST	Q9UH77	KLHL3	P17252	PRKCA	S376	G369S	369	Missense	distal	-7	no	17.233	17.237	EPSD	GDSC;CCLE	16.704	Up-regulation
AGC_PKC_PKCa_PRKCA_ST	Q9UH77	KLHL3	P17252	PRKCA	S376	V370M	370	Missense	distal	-6	no	17.233	17.344	EPSD	GDSC;CCLE	16.704	Up-regulation
AGC_PKC_PKCa_PRKCA_ST	Q9UH77	KLHL3	P17252	PRKCA	S433	V436M	436	Missense	distal	3	no	18.860	19.446	PhosphoSitePlus	GDSC;CCLE	16.704	Up-regulation
AGC_PKC_PKCa_PRKCA_ST	Q9BQE3	TUBA1C	P17252	PRKCA	S232	Q233R	233	Missense	proximal	1	no	17.007	17.124	EPSD	GDSC	16.704	Up-regulation
AGC_PKC_PKCa_PRKCA_ST	Q15139	PRKD1	P17252	PRKCA	S412	R408M	408	Missense	distal	-4	no	20.971	21.050	EPSD	GDSC;CCLE	16.704	Up-regulation
AGC_PKC_PKCa_PRKCA_ST	Q15139	PRKD1	P17252	PRKCA	T458	S460R	460	Missense	proximal	2	no	13.804	18.424	EPSD	GDSC	16.704	Gain
AGC_PKC_PKCa_PRKCA_ST	Q15139	PRKD1	P17252	PRKCA	S829	K826E	826	Missense	distal	-3	no	19.730	16.818	EPSD	GDSC;CCLE	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	P17302	GJA1	P17252	PRKCA	S262	S262P	262	Missense	central	0	yes	18.371	0.000	EPSD	GDSC;CCLE	16.704	Loss
AGC_PKC_PKCa_PRKCA_ST	P17302	GJA1	P17252	PRKCA	S262	Q263*	263	Missense	proximal	1	no	18.371	17.617	EPSD	GDSC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	P17302	GJA1	P17252	PRKCA	S296	G291D	291	Missense	distal	-5	no	17.041	16.946	EPSD	GDSC;CCLE	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	P17302	GJA1	P17252	PRKCA	S296	R299C	299	Missense	distal	3	no	17.041	14.423	EPSD	GDSC;CCLE	16.704	Loss
AGC_PKC_PKCa_PRKCA_ST	P17302	GJA1	P17252	PRKCA	S296	V289G	289	Missense	distal	-7	no	17.041	17.045	EPSD	GDSC;CCLE	16.704	Up-regulation
AGC_PKC_PKCa_PRKCA_ST	P17302	GJA1	P17252	PRKCA	S296	D292G	292	Missense	distal	-4	no	17.041	17.811	EPSD	GDSC;CCLE	16.704	Up-regulation
AGC_PKC_PKCa_PRKCA_ST	P00533	EGFR	P17252	PRKCA	S1162	W1157C	1157	Missense	distal	-5	no	16.914	16.553	EPSD	GDSC;CCLE	16.704	Loss
AGC_PKC_PKCa_PRKCA_ST	P02786	TFRC	P17252	PRKCA	T572	T569S	569	Missense	distal	-3	no	15.426	16.719	EPSD	GDSC;CCLE	16.704	Gain
AGC_PKC_PKCa_PRKCA_ST	P02786	TFRC	P17252	PRKCA	S654	G661R	661	Missense	distal	7	no	16.775	16.799	EPSD	GDSC;CCLE	16.704	Up-regulation
AGC_PKC_PKCa_PRKCA_ST	P10721	KIT	P17252	PRKCA	S628	K626R	626	Missense	proximal	-2	no	15.898	17.526	EPSD	GDSC;CCLE	16.704	Gain
AGC_PKC_PKCa_PRKCA_ST	P10721	KIT	P17252	PRKCA	S741	D737H	737	Missense	distal	-4	no	22.542	22.840	PhosphoSitePlus;EPSD	GDSC;CCLE	16.704	Up-regulation
AGC_PKC_PKCa_PRKCA_ST	P10721	KIT	P17252	PRKCA	S891	A895E	895	Missense	distal	4	no	17.821	17.682	EPSD	GDSC;CCLE	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	O60928	KCNJ13	P17252	PRKCA	S14	R18Q	18	Missense	distal	4	no	20.336	20.119	EPSD	GDSC;CCLE	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	O60928	KCNJ13	P17252	PRKCA	S287	T286I	286	Missense	proximal	-1	no	19.566	18.661	EPSD	GDSC;CCLE	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	O60928	KCNJ13	P17252	PRKCA	S287	C282*	282	Missense	distal	-5	no	19.566	19.620	EPSD	GDSC	16.704	Up-regulation
AGC_PKC_PKCa_PRKCA_ST	O60928	KCNJ13	P17252	PRKCA	S331	P328R	328	Missense	distal	-3	no	12.984	16.833	EPSD	GDSC;CCLE	16.704	Gain
AGC_PKC_PKCa_PRKCA_ST	Q13976	PRKG1	P17252	PRKCA	S27	Q34E	34	Missense	distal	7	no	23.289	23.198	EPSD	GDSC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	O75376	NCOR1	P17252	PRKCA	S88	R85S	85	Missense	distal	-3	no	17.988	15.118	EPSD	GDSC;CCLE	16.704	Loss
AGC_PKC_PKCa_PRKCA_ST	O75376	NCOR1	P17252	PRKCA	S88	P91L	91	Missense	distal	3	no	17.988	17.281	EPSD	GDSC;CCLE	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	O75376	NCOR1	P17252	PRKCA	S106	P109L	109	Missense	distal	3	no	20.474	19.767	EPSD	GDSC;CCLE	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	O75376	NCOR1	P17252	PRKCA	T568	Q566K	566	Missense	proximal	-2	no	18.285	18.417	EPSD	GDSC	16.704	Up-regulation
AGC_PKC_PKCa_PRKCA_ST	O75376	NCOR1	P17252	PRKCA	T1443	R1445H	1445	Missense	proximal	2	no	16.827	11.804	EPSD	GDSC;CCLE	16.704	Loss
AGC_PKC_PKCa_PRKCA_ST	O75376	NCOR1	P17252	PRKCA	T1443	V1438A	1438	Missense	distal	-5	no	16.827	16.911	EPSD	GDSC	16.704	Up-regulation
AGC_PKC_PKCa_PRKCA_ST	O75376	NCOR1	P17252	PRKCA	S1480	S1480G	1480	Missense	central	0	yes	17.271	0.000	EPSD	GDSC	16.704	Loss
AGC_PKC_PKCa_PRKCA_ST	O75376	NCOR1	P17252	PRKCA	S1760	M1767I	1767	Missense	distal	7	no	17.669	17.505	EPSD	GDSC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	O75376	NCOR1	P17252	PRKCA	S1760	M1767V	1767	Missense	distal	7	no	17.669	17.601	EPSD	GDSC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	O75376	NCOR1	P17252	PRKCA	S1963	S1962Y	1962	Missense	proximal	-1	no	17.446	16.996	EPSD	GDSC;CCLE	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	O75376	NCOR1	P17252	PRKCA	S1963	Y1966*	1966	Missense	distal	3	no	17.446	16.640	EPSD	GDSC	16.704	Loss
AGC_PKC_PKCa_PRKCA_ST	O75376	NCOR1	P17252	PRKCA	S2117	R2118S	2118	Missense	proximal	1	no	17.620	16.446	EPSD	GDSC;CCLE	16.704	Loss
AGC_PKC_PKCa_PRKCA_ST	O75376	NCOR1	P17252	PRKCA	S2131	D2126N	2126	Missense	distal	-5	no	18.522	18.551	EPSD	GDSC;CCLE	16.704	Up-regulation
AGC_PKC_PKCa_PRKCA_ST	O75376	NCOR1	P17252	PRKCA	S2169	E2174*	2174	Missense	distal	5	no	18.482	18.341	EPSD	GDSC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	O75376	NCOR1	P17252	PRKCA	S2335	K2329T	2329	Missense	distal	-6	no	17.167	16.976	EPSD	GDSC;CCLE	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	O75376	NCOR1	P17252	PRKCA	S2394	S2395N	2395	Missense	proximal	1	no	18.118	18.164	EPSD	GDSC;CCLE	16.704	Up-regulation
AGC_PKC_PKCa_PRKCA_ST	Q9UQ13	SHOC2	P17252	PRKCA	S85	P79H	79	Missense	distal	-6	no	17.159	17.196	EPSD	GDSC;CCLE	16.704	Up-regulation
AGC_PKC_PKCa_PRKCA_ST	Q9UQ13	SHOC2	P17252	PRKCA	S221	K226T	226	Missense	distal	5	no	22.884	22.424	EPSD	GDSC;CCLE	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	Q9UQ13	SHOC2	P17252	PRKCA	S297	A304V	304	Missense	distal	7	no	17.386	17.331	PhosphoSitePlus;EPSD	GDSC;CCLE	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	P29350	PTPN6	P17252	PRKCA	S10	R7*	7	Missense	distal	-3	no	18.049	12.505	EPSD	GDSC	16.704	Loss
AGC_PKC_PKCa_PRKCA_ST	P29350	PTPN6	P17252	PRKCA	S32	D38E	38	Missense	distal	6	no	20.658	20.641	EPSD	GDSC;CCLE	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	P29350	PTPN6	P17252	PRKCA	S32	F39V	39	Missense	distal	7	no	20.658	20.665	EPSD	GDSC;CCLE	16.704	Up-regulation
AGC_PKC_PKCa_PRKCA_ST	P29350	PTPN6	P17252	PRKCA	S42	D38E	38	Missense	distal	-4	no	17.466	17.642	EPSD	GDSC;CCLE	16.704	Up-regulation
AGC_PKC_PKCa_PRKCA_ST	P29350	PTPN6	P17252	PRKCA	S42	F39V	39	Missense	distal	-3	no	17.466	16.397	EPSD	GDSC;CCLE	16.704	Loss
AGC_PKC_PKCa_PRKCA_ST	P29350	PTPN6	P17252	PRKCA	S528	S534L	534	Missense	distal	6	no	20.008	19.997	EPSD	GDSC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	O60674	JAK2	P17252	PRKCA	S936	Y934N	934	Missense	proximal	-2	no	16.865	16.397	EPSD	GDSC;CCLE	16.704	Loss
AGC_PKC_PKCa_PRKCA_ST	P42261	GRIA1	P17252	PRKCA	S306	D313Y	313	Missense	distal	7	no	19.207	19.199	EPSD	GDSC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	P42261	GRIA1	P17252	PRKCA	S306	R308L	308	Missense	proximal	2	no	19.207	14.220	EPSD	GDSC	16.704	Loss
AGC_PKC_PKCa_PRKCA_ST	P42261	GRIA1	P17252	PRKCA	T858	S863I	863	Missense	distal	5	no	17.098	16.904	EPSD	GDSC;CCLE	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	P42261	GRIA1	P17252	PRKCA	T858	T858P	858	Missense	central	0	yes	17.098	0.000	EPSD	GDSC	16.704	Loss
AGC_PKC_PKCa_PRKCA_ST	P35869	AHR	P17252	PRKCA	S12	T9P	9	Missense	distal	-3	no	21.715	22.030	PhosphoSitePlus;EPSD	GDSC;CCLE	16.704	Up-regulation
AGC_PKC_PKCa_PRKCA_ST	P35869	AHR	P17252	PRKCA	S12	R15W	15	Missense	distal	3	no	21.715	18.782	PhosphoSitePlus;EPSD	GDSC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	P35869	AHR	P17252	PRKCA	S36	P35H	35	Missense	proximal	-1	no	21.241	21.605	EPSD;PhosphoSitePlus	GDSC;CCLE	16.704	Up-regulation
AGC_PKC_PKCa_PRKCA_ST	P35611	ADD1	P17252	PRKCA	S358	T364A	364	Missense	distal	6	no	17.039	17.117	EPSD	GDSC;CCLE	16.704	Up-regulation
AGC_PKC_PKCa_PRKCA_ST	P35611	ADD1	P17252	PRKCA	S404	E411A	411	Missense	distal	7	no	20.626	20.674	EPSD	GDSC;CCLE	16.704	Up-regulation
AGC_PKC_PKCa_PRKCA_ST	P49802	RGS7	P17252	PRKCA	S218	S217P	217	Missense	proximal	-1	no	18.906	18.606	EPSD	GDSC;CCLE	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	P49802	RGS7	P17252	PRKCA	S323	S319N	319	Missense	distal	-4	no	17.009	16.679	EPSD	GDSC	16.704	Loss
AGC_PKC_PKCa_PRKCA_ST	P49802	RGS7	P17252	PRKCA	S463	A468T	468	Missense	distal	5	no	20.138	19.859	EPSD	GDSC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	P35503	UGT1A3	P17252	PRKCA	S43	R49Q	49	Missense	distal	6	no	18.448	18.325	PhosphoSitePlus	GDSC;CCLE	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	Q99801	NKX3-1	P17252	PRKCA	S48	S48R	48	Missense	central	0	yes	22.062	0.000	PhosphoSitePlus	GDSC;CCLE	16.704	Loss
AGC_PKC_PKCa_PRKCA_ST	Q99801	NKX3-1	P17252	PRKCA	S48	P54T	54	Missense	distal	6	no	22.062	21.980	PhosphoSitePlus	GDSC;CCLE	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	Q13224	GRIN2B	P17252	PRKCA	S1043	G1040S	1040	Missense	distal	-3	no	19.592	19.984	EPSD	GDSC;CCLE	16.704	Up-regulation
AGC_PKC_PKCa_PRKCA_ST	Q13224	GRIN2B	P17252	PRKCA	T1410	P1409L	1409	Missense	proximal	-1	no	18.718	18.599	EPSD	GDSC;CCLE	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	Q96MS0	ROBO3	P17252	PRKCA	S1293	M1291I	1291	Missense	proximal	-2	no	16.763	15.157	EPSD	GDSC;CCLE	16.704	Loss
AGC_PKC_PKCa_PRKCA_ST	P06127	CD5	P17252	PRKCA	T142	P146Q	146	Missense	distal	4	no	17.394	17.623	EPSD	GDSC;CCLE	16.704	Up-regulation
AGC_PKC_PKCa_PRKCA_ST	P06127	CD5	P17252	PRKCA	T436	V437I	437	Missense	proximal	1	no	16.941	17.653	EPSD;PhosphoSitePlus	GDSC;CCLE	16.704	Up-regulation
AGC_PKC_PKCa_PRKCA_ST	P06239	LCK	P17252	PRKCA	S42	R45Q	45	Missense	distal	3	no	18.146	15.693	PhosphoSitePlus	GDSC	16.704	Loss
AGC_PKC_PKCa_PRKCA_ST	P06239	LCK	P17252	PRKCA	S42	S42L	42	Missense	central	0	yes	18.146	0.000	PhosphoSitePlus	GDSC	16.704	Loss
AGC_PKC_PKCa_PRKCA_ST	P06239	LCK	P17252	PRKCA	S166	V167I	167	Missense	proximal	1	no	18.998	19.710	EPSD	GDSC;CCLE	16.704	Up-regulation
AGC_PKC_PKCa_PRKCA_ST	P32004	L1CAM	P17252	PRKCA	T527	R534G	534	Missense	distal	7	no	16.781	16.757	EPSD	GDSC;CCLE	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	Q01959	SLC6A3	P17252	PRKCA	S2	V8M	8	Missense	distal	6	no	18.203	18.291	EPSD	GDSC;CCLE	16.704	Up-regulation
AGC_PKC_PKCa_PRKCA_ST	Q01959	SLC6A3	P17252	PRKCA	S262	S262P	262	Missense	central	0	yes	17.762	0.000	EPSD	GDSC;CCLE	16.704	Loss
AGC_PKC_PKCa_PRKCA_ST	P28329	CHAT	P17252	PRKCA	S244	D250G	250	Missense	distal	6	no	17.598	17.538	EPSD	GDSC;CCLE	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	P28329	CHAT	P17252	PRKCA	S464	S465R	465	Missense	proximal	1	no	18.756	19.930	EPSD	GDSC;CCLE	16.704	Up-regulation
AGC_PKC_PKCa_PRKCA_ST	P28329	CHAT	P17252	PRKCA	S465	S465R	465	Missense	central	0	yes	18.460	0.000	EPSD	GDSC;CCLE	16.704	Loss
AGC_PKC_PKCa_PRKCA_ST	P28329	CHAT	P17252	PRKCA	S473	P478L	478	Missense	distal	5	no	18.312	17.962	EPSD	GDSC;CCLE	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	P28329	CHAT	P17252	PRKCA	S473	P480S	480	Missense	distal	7	no	18.312	18.275	EPSD	GDSC;CCLE	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	P28329	CHAT	P17252	PRKCA	S473	P480L	480	Missense	distal	7	no	18.312	18.278	EPSD	GDSC;CCLE	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	P28329	CHAT	P17252	PRKCA	S558	E555D	555	Missense	distal	-3	no	19.146	19.042	EPSD	GDSC;CCLE	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	P06401	PGR	P17252	PRKCA	S162	R167Q	167	Missense	distal	5	no	17.409	17.400	EPSD	GDSC;CCLE	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	P06401	PGR	P17252	PRKCA	S276	F275S	275	Missense	proximal	-1	no	17.207	17.914	EPSD	GDSC;CCLE	16.704	Up-regulation
AGC_PKC_PKCa_PRKCA_ST	P06401	PGR	P17252	PRKCA	S397	E395G	395	Missense	proximal	-2	no	15.593	16.848	EPSD	GDSC;CCLE	16.704	Gain
AGC_PKC_PKCa_PRKCA_ST	P06401	PGR	P17252	PRKCA	S400	E395G	395	Missense	distal	-5	no	17.185	17.202	PhosphoSitePlus	GDSC;CCLE	16.704	Up-regulation
AGC_PKC_PKCa_PRKCA_ST	Q8N556	AFAP1	P17252	PRKCA	S307	S310L	310	Missense	distal	3	no	22.757	21.911	EPSD	GDSC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	Q8N556	AFAP1	P17252	PRKCA	S307	E311Q	311	Missense	distal	4	no	22.757	22.908	EPSD	GDSC;CCLE	16.704	Up-regulation
AGC_PKC_PKCa_PRKCA_ST	Q8N556	AFAP1	P17252	PRKCA	S308	S310L	310	Missense	proximal	2	no	17.992	17.625	EPSD	GDSC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	Q8N556	AFAP1	P17252	PRKCA	S308	E311Q	311	Missense	distal	3	no	17.992	16.778	EPSD	GDSC;CCLE	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	Q8N556	AFAP1	P17252	PRKCA	S531	L530I	530	Missense	proximal	-1	no	16.713	15.849	EPSD	GDSC	16.704	Loss
AGC_PKC_PKCa_PRKCA_ST	Q96T49	PPP1R16B	P17252	PRKCA	S350	D353N	353	Missense	distal	3	no	18.950	19.105	EPSD	GDSC;CCLE	16.704	Up-regulation
AGC_PKC_PKCa_PRKCA_ST	Q8TD43	TRPM4	P17252	PRKCA	S541	S536T	536	Missense	distal	-5	no	18.869	19.197	EPSD	GDSC	16.704	Up-regulation
AGC_PKC_PKCa_PRKCA_ST	Q8TD43	TRPM4	P17252	PRKCA	S1098	S1102A	1102	Missense	distal	4	no	19.660	19.677	EPSD	GDSC;CCLE	16.704	Up-regulation
AGC_PKC_PKCa_PRKCA_ST	Q8TD43	TRPM4	P17252	PRKCA	S1143	R1147C	1147	Missense	distal	4	no	16.763	15.362	EPSD	GDSC;CCLE	16.704	Loss
AGC_PKC_PKCa_PRKCA_ST	Q8TD43	TRPM4	P17252	PRKCA	S1152	R1147C	1147	Missense	distal	-5	no	20.781	20.106	PhosphoSitePlus;EPSD	GDSC;CCLE	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	Q969H0	FBXW7	P17252	PRKCA	S10	R13*	13	Missense	distal	3	no	25.231	22.157	PhosphoSitePlus;EPSD	GDSC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	Q969H0	FBXW7	P17252	PRKCA	S10	K11Q	11	Missense	proximal	1	no	25.231	25.077	PhosphoSitePlus;EPSD	GDSC;CCLE	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	Q969H0	FBXW7	P17252	PRKCA	S18	R13*	13	Missense	distal	-5	no	20.808	20.187	EPSD;PhosphoSitePlus	GDSC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	Q969H0	FBXW7	P17252	PRKCA	S18	K11Q	11	Missense	distal	-7	no	20.808	20.805	EPSD;PhosphoSitePlus	GDSC;CCLE	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	P11473	VDR	P17252	PRKCA	S7	S9F	9	Missense	proximal	2	no	16.584	16.901	EPSD	GDSC;CCLE	16.704	Gain
AGC_PKC_PKCa_PRKCA_ST	Q9NPC2	KCNK9	P17252	PRKCA	T341	I337F	337	Missense	distal	-4	no	17.927	18.310	PhosphoSitePlus	GDSC;CCLE	16.704	Up-regulation
AGC_PKC_PKCa_PRKCA_ST	Q9NPC2	KCNK9	P17252	PRKCA	S373	S373F	373	Missense	central	0	yes	16.743	0.000	EPSD	GDSC;CCLE	16.704	Loss
AGC_PKC_PKCa_PRKCA_ST	Q14184	DOC2B	P17252	PRKCA	T211	R213W	213	Missense	proximal	2	no	18.057	12.618	EPSD	GDSC	16.704	Loss
AGC_PKC_PKCa_PRKCA_ST	P41180	CASR	P17252	PRKCA	S342	H344Y	344	Missense	proximal	2	no	16.182	16.710	EPSD	GDSC;CCLE	16.704	Gain
AGC_PKC_PKCa_PRKCA_ST	P41180	CASR	P17252	PRKCA	T888	V894G	894	Missense	distal	6	no	17.986	17.997	PhosphoSitePlus	GDSC;CCLE	16.704	Up-regulation
AGC_PKC_PKCa_PRKCA_ST	P41180	CASR	P17252	PRKCA	S895	V894G	894	Missense	proximal	-1	no	19.647	21.357	EPSD	GDSC;CCLE	16.704	Up-regulation
AGC_PKC_PKCa_PRKCA_ST	P41180	CASR	P17252	PRKCA	S899	S905Y	905	Missense	distal	6	no	17.285	17.304	EPSD	GDSC;CCLE	16.704	Up-regulation
AGC_PKC_PKCa_PRKCA_ST	P41180	CASR	P17252	PRKCA	S899	V894G	894	Missense	distal	-5	no	17.285	17.558	EPSD	GDSC;CCLE	16.704	Up-regulation
AGC_PKC_PKCa_PRKCA_ST	P41180	CASR	P17252	PRKCA	S900	S905Y	905	Missense	distal	5	no	17.164	17.191	EPSD	GDSC;CCLE	16.704	Up-regulation
AGC_PKC_PKCa_PRKCA_ST	P41180	CASR	P17252	PRKCA	S900	V894G	894	Missense	distal	-6	no	17.164	17.244	EPSD	GDSC;CCLE	16.704	Up-regulation
AGC_PKC_PKCa_PRKCA_ST	P41180	CASR	P17252	PRKCA	S901	S905Y	905	Missense	distal	4	no	16.908	16.510	EPSD	GDSC;CCLE	16.704	Loss
AGC_PKC_PKCa_PRKCA_ST	P41180	CASR	P17252	PRKCA	S901	V894G	894	Missense	distal	-7	no	16.908	16.912	EPSD	GDSC;CCLE	16.704	Up-regulation
AGC_PKC_PKCa_PRKCA_ST	P41180	CASR	P17252	PRKCA	S915	S916I	916	Missense	proximal	1	no	16.458	18.120	EPSD	GDSC;CCLE	16.704	Gain
AGC_PKC_PKCa_PRKCA_ST	Q8NFA2	NOXO1	P17252	PRKCA	S159	Q166*	166	Missense	distal	7	no	17.846	17.724	EPSD	GDSC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	P16070	CD44	P17252	PRKCA	S183	E185K	185	Missense	proximal	2	no	12.939	18.218	EPSD	GDSC;CCLE	16.704	Gain
AGC_PKC_PKCa_PRKCA_ST	P16070	CD44	P17252	PRKCA	S184	E185K	185	Missense	proximal	1	no	16.155	17.759	EPSD	GDSC;CCLE	16.704	Gain
AGC_PKC_PKCa_PRKCA_ST	O14939	PLD2	P17252	PRKCA	S155	R149Q	149	Missense	distal	-6	no	18.533	18.390	EPSD	GDSC;CCLE	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	O14939	PLD2	P17252	PRKCA	T274	R281W	281	Missense	distal	7	no	17.364	17.184	EPSD	GDSC;CCLE	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	O14939	PLD2	P17252	PRKCA	T274	Q268*	268	Missense	distal	-6	no	17.364	17.260	EPSD	GDSC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	O14939	PLD2	P17252	PRKCA	T488	P487T	487	Missense	proximal	-1	no	16.907	16.828	EPSD	GDSC;CCLE	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	Q5JVS0	HABP4	P17252	PRKCA	T121	R120P	120	Missense	proximal	-1	no	18.879	18.192	EPSD	GDSC;CCLE	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	Q5JVS0	HABP4	P17252	PRKCA	T375	R376Q	376	Missense	proximal	1	no	18.122	18.005	PhosphoSitePlus;EPSD	GDSC;CCLE	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	Q9BZL6	PRKD2	P17252	PRKCA	T412	T412M	412	Missense	central	0	yes	17.328	0.000	EPSD	GDSC;CCLE	16.704	Loss
AGC_PKC_PKCa_PRKCA_ST	Q9BZL6	PRKD2	P17252	PRKCA	S706	R708C	708	Missense	proximal	2	no	20.420	16.070	EPSD;PhosphoSitePlus	GDSC;CCLE	16.704	Loss
AGC_PKC_PKCa_PRKCA_ST	Q9BZL6	PRKD2	P17252	PRKCA	S710	R708C	708	Missense	proximal	-2	no	20.269	18.569	EPSD;PhosphoSitePlus	GDSC;CCLE	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	Q13002	GRIK2	P17252	PRKCA	S361	T357P	357	Missense	distal	-4	no	16.683	17.173	EPSD	GDSC;CCLE	16.704	Gain
AGC_PKC_PKCa_PRKCA_ST	Q13002	GRIK2	P17252	PRKCA	S393	I392N	392	Missense	proximal	-1	no	15.869	16.994	EPSD	GDSC;CCLE	16.704	Gain
AGC_PKC_PKCa_PRKCA_ST	Q13002	GRIK2	P17252	PRKCA	S416	A422V	422	Missense	distal	6	no	21.070	20.951	EPSD	GDSC;CCLE	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	Q13002	GRIK2	P17252	PRKCA	S715	K719R	719	Missense	distal	4	no	20.252	20.081	EPSD	GDSC;CCLE	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	Q13002	GRIK2	P17252	PRKCA	S868	V862I	862	Missense	distal	-6	no	22.309	22.325	PhosphoSitePlus	GDSC	16.704	Up-regulation
AGC_PKC_PKCa_PRKCA_ST	Q13002	GRIK2	P17252	PRKCA	S868	L875F	875	Missense	distal	7	no	22.309	22.242	PhosphoSitePlus	GDSC;CCLE	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	Q96C90	PPP1R14B	P17252	PRKCA	T57	Q53E	53	Missense	distal	-4	no	16.993	16.674	PhosphoSitePlus	GDSC;CCLE	16.704	Loss
AGC_PKC_PKCa_PRKCA_ST	O14920	IKBKB	P17252	PRKCA	S239	D242N	242	Missense	distal	3	no	16.568	16.723	EPSD	GDSC;CCLE	16.704	Gain
AGC_PKC_PKCa_PRKCA_ST	O14920	IKBKB	P17252	PRKCA	S682	G685W	685	Missense	distal	3	no	18.847	16.553	EPSD	GDSC;CCLE	16.704	Loss
AGC_PKC_PKCa_PRKCA_ST	O14920	IKBKB	P17252	PRKCA	S692	G685W	685	Missense	distal	-7	no	17.166	17.159	EPSD	GDSC;CCLE	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	O60500	NPHS1	P17252	PRKCA	T305	H311Q	311	Missense	distal	6	no	19.529	19.484	EPSD	GDSC;CCLE	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	P09693	CD3G	P17252	PRKCA	S145	S148L	148	Missense	distal	3	no	17.931	17.085	EPSD	GDSC;CCLE	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	P09693	CD3G	P17252	PRKCA	S145	S145*	145	Missense	central	0	yes	17.931	0.000	EPSD	GDSC	16.704	Loss
AGC_PKC_PKCa_PRKCA_ST	P09693	CD3G	P17252	PRKCA	S148	S148L	148	Missense	central	0	yes	20.548	0.000	PhosphoSitePlus	GDSC;CCLE	16.704	Loss
AGC_PKC_PKCa_PRKCA_ST	P09693	CD3G	P17252	PRKCA	S148	S145*	145	Missense	distal	-3	no	20.548	17.873	PhosphoSitePlus	GDSC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	Q16875	PFKFB3	P17252	PRKCA	S478	R475H	475	Missense	distal	-3	no	16.721	12.864	EPSD	GDSC;CCLE	16.704	Loss
AGC_PKC_PKCa_PRKCA_ST	P09211	GSTP1	P17252	PRKCA	S43	W39*	39	Missense	distal	-4	no	17.670	17.701	EPSD	GDSC	16.704	Up-regulation
AGC_PKC_PKCa_PRKCA_ST	Q01970	PLCB3	P17252	PRKCA	S68	R70G	70	Missense	proximal	2	no	18.185	12.940	EPSD	GDSC;CCLE	16.704	Loss
AGC_PKC_PKCa_PRKCA_ST	Q01970	PLCB3	P17252	PRKCA	S474	R472Q	472	Missense	proximal	-2	no	17.287	15.528	EPSD	GDSC;CCLE	16.704	Loss
AGC_PKC_PKCa_PRKCA_ST	Q01970	PLCB3	P17252	PRKCA	S1105	R1102C	1102	Missense	distal	-3	no	18.595	15.856	PhosphoSitePlus	GDSC;CCLE	16.704	Loss
AGC_PKC_PKCa_PRKCA_ST	Q01995	TAGLN	P17252	PRKCA	S181	Q178H	178	Missense	distal	-3	no	18.986	17.987	PhosphoSitePlus	GDSC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	Q01995	TAGLN	P17252	PRKCA	S181	Q187R	187	Missense	distal	6	no	18.986	19.109	PhosphoSitePlus	GDSC;CCLE	16.704	Up-regulation
AGC_PKC_PKCa_PRKCA_ST	O94759	TRPM2	P17252	PRKCA	S11	L6P	6	Missense	distal	-5	no	18.101	18.127	EPSD	GDSC;CCLE	16.704	Up-regulation
AGC_PKC_PKCa_PRKCA_ST	O94901	SUN1	P17252	PRKCA	S48	V45A	45	Missense	distal	-3	no	17.195	16.436	EPSD	GDSC	16.704	Loss
AGC_PKC_PKCa_PRKCA_ST	O94901	SUN1	P17252	PRKCA	S52	V45A	45	Missense	distal	-7	no	22.535	22.545	EPSD	GDSC	16.704	Up-regulation
AGC_PKC_PKCa_PRKCA_ST	O94901	SUN1	P17252	PRKCA	S82	R86P	86	Missense	distal	4	no	16.743	16.297	EPSD	GDSC	16.704	Loss
AGC_PKC_PKCa_PRKCA_ST	O94901	SUN1	P17252	PRKCA	S82	S79G	79	Missense	distal	-3	no	16.743	16.352	EPSD	GDSC	16.704	Loss
AGC_PKC_PKCa_PRKCA_ST	O94901	SUN1	P17252	PRKCA	S82	R86Q	86	Missense	distal	4	no	16.743	16.526	EPSD	GDSC;CCLE	16.704	Loss
AGC_PKC_PKCa_PRKCA_ST	O94901	SUN1	P17252	PRKCA	T370	V365M	365	Missense	distal	-5	no	16.458	16.856	EPSD	GDSC	16.704	Gain
AGC_PKC_PKCa_PRKCA_ST	Q9C0K0	BCL11B	P17252	PRKCA	S765	L764F	764	Missense	proximal	-1	no	17.505	17.217	EPSD	GDSC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	Q9C0K0	BCL11B	P17252	PRKCA	S795	C798R	798	Missense	distal	3	no	16.651	19.269	EPSD	GDSC;CCLE	16.704	Gain
AGC_PKC_PKCa_PRKCA_ST	Q9C0K0	BCL11B	P17252	PRKCA	S817	R822Q	822	Missense	distal	5	no	21.134	21.125	EPSD	GDSC;CCLE	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	Q9C0K0	BCL11B	P17252	PRKCA	S817	T812A	812	Missense	distal	-5	no	21.134	20.753	EPSD	GDSC;CCLE	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	P50552	VASP	P17252	PRKCA	S157	R155Q	155	Missense	proximal	-2	no	18.806	17.047	PhosphoSitePlus	GDSC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	P50552	VASP	P17252	PRKCA	S157	N158H	158	Missense	proximal	1	no	18.806	19.119	PhosphoSitePlus	GDSC	16.704	Up-regulation
AGC_PKC_PKCa_PRKCA_ST	P30411	BDKRB2	P17252	PRKCA	S12	D16A	16	Missense	distal	4	no	20.839	21.208	EPSD	GDSC	16.704	Up-regulation
AGC_PKC_PKCa_PRKCA_ST	P30411	BDKRB2	P17252	PRKCA	S12	M9T	9	Missense	distal	-3	no	20.839	19.648	EPSD	GDSC;CCLE	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	Q01954	BNC1	P17252	PRKCA	S398	S398Y	398	Missense	central	0	yes	17.878	0.000	EPSD	GDSC;CCLE	16.704	Loss
AGC_PKC_PKCa_PRKCA_ST	Q01954	BNC1	P17252	PRKCA	S398	R400S	400	Missense	proximal	2	no	17.878	13.259	EPSD	GDSC;CCLE	16.704	Loss
AGC_PKC_PKCa_PRKCA_ST	Q01954	BNC1	P17252	PRKCA	S938	T942A	942	Missense	distal	4	no	17.817	18.264	EPSD	GDSC	16.704	Up-regulation
AGC_PKC_PKCa_PRKCA_ST	Q01954	BNC1	P17252	PRKCA	S938	R944M	944	Missense	distal	6	no	17.817	17.744	EPSD	GDSC;CCLE	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	Q01954	BNC1	P17252	PRKCA	T942	T942A	942	Missense	central	0	yes	17.837	0.000	EPSD	GDSC	16.704	Loss
AGC_PKC_PKCa_PRKCA_ST	Q01954	BNC1	P17252	PRKCA	T942	R944M	944	Missense	proximal	2	no	17.837	13.389	EPSD	GDSC;CCLE	16.704	Loss
AGC_PKC_PKCa_PRKCA_ST	Q14524	SCN5A	P17252	PRKCA	S11	S11I	11	Missense	central	0	yes	20.342	0.000	EPSD	GDSC;CCLE	16.704	Loss
AGC_PKC_PKCa_PRKCA_ST	Q14524	SCN5A	P17252	PRKCA	S12	S11I	11	Missense	proximal	-1	no	24.060	22.777	EPSD	GDSC;CCLE	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	Q14524	SCN5A	P17252	PRKCA	T17	S11I	11	Missense	distal	-6	no	18.215	18.118	EPSD	GDSC;CCLE	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	Q14524	SCN5A	P17252	PRKCA	S476	R475S	475	Missense	proximal	-1	no	23.937	23.549	EPSD	GDSC;CCLE	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	Q14524	SCN5A	P17252	PRKCA	S476	S471N	471	Missense	distal	-5	no	23.937	24.008	EPSD	GDSC;CCLE	16.704	Up-regulation
AGC_PKC_PKCa_PRKCA_ST	Q14524	SCN5A	P17252	PRKCA	S516	T512I	512	Missense	distal	-4	no	16.590	16.810	EPSD	GDSC;CCLE	16.704	Gain
AGC_PKC_PKCa_PRKCA_ST	Q14524	SCN5A	P17252	PRKCA	S519	T512I	512	Missense	distal	-7	no	21.739	21.732	EPSD	GDSC;CCLE	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	Q14524	SCN5A	P17252	PRKCA	T531	G538A	538	Missense	distal	7	no	20.137	20.113	EPSD	GDSC;CCLE	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	Q14524	SCN5A	P17252	PRKCA	S571	A572D	572	Missense	proximal	1	no	22.789	21.565	EPSD	GDSC	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	Q14524	SCN5A	P17252	PRKCA	S571	T570I	570	Missense	proximal	-1	no	22.789	21.884	EPSD	GDSC;CCLE	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	Q14524	SCN5A	P17252	PRKCA	S571	P576H	576	Missense	distal	5	no	22.789	22.511	EPSD	GDSC;CCLE	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	Q14524	SCN5A	P17252	PRKCA	S571	R569G	569	Missense	proximal	-2	no	22.789	19.917	EPSD	GDSC;CCLE	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	Q14524	SCN5A	P17252	PRKCA	S581	P576H	576	Missense	distal	-5	no	16.895	16.641	EPSD	GDSC;CCLE	16.704	Loss
AGC_PKC_PKCa_PRKCA_ST	P35900	KRT20	P17252	PRKCA	S11	R5H	5	Missense	distal	-6	no	18.157	18.090	EPSD	GDSC;CCLE	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	P35900	KRT20	P17252	PRKCA	S118	A119V	119	Missense	proximal	1	no	16.820	16.973	EPSD	GDSC;CCLE	16.704	Up-regulation
AGC_PKC_PKCa_PRKCA_ST	Q71U36	TUBA1A	P17252	PRKCA	T82	G81D	81	Missense	proximal	-1	no	19.353	18.610	EPSD	GDSC;CCLE	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	Q01844	EWSR1	P17252	PRKCA	S259	Q256*	256	Missense	distal	-3	no	17.340	14.654	EPSD	GDSC	16.704	Loss
AGC_PKC_PKCa_PRKCA_ST	P14416	DRD2	P17252	PRKCA	T225	R227L	227	Missense	proximal	2	no	21.887	16.900	EPSD	GDSC;CCLE	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	P14416	DRD2	P17252	PRKCA	S228	R227L	227	Missense	proximal	-1	no	18.941	18.134	EPSD;PhosphoSitePlus	GDSC;CCLE	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	P14416	DRD2	P17252	PRKCA	S228	T225S	225	Missense	distal	-3	no	18.941	20.234	EPSD;PhosphoSitePlus	GDSC;CCLE	16.704	Up-regulation
AGC_PKC_PKCa_PRKCA_ST	P14416	DRD2	P17252	PRKCA	S229	R227L	227	Missense	proximal	-2	no	17.910	15.222	PhosphoSitePlus;EPSD	GDSC;CCLE	16.704	Loss
AGC_PKC_PKCa_PRKCA_ST	P14416	DRD2	P17252	PRKCA	S229	T225S	225	Missense	distal	-4	no	17.910	18.571	PhosphoSitePlus;EPSD	GDSC;CCLE	16.704	Up-regulation
AGC_PKC_PKCa_PRKCA_ST	P14416	DRD2	P17252	PRKCA	S354	M358I	358	Missense	distal	4	no	21.245	19.750	EPSD	GDSC;CCLE	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	P14416	DRD2	P17252	PRKCA	S354	R361W	361	Missense	distal	7	no	21.245	21.064	EPSD	GDSC;CCLE	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	P14416	DRD2	P17252	PRKCA	S359	M358I	358	Missense	proximal	-1	no	22.387	20.445	EPSD	GDSC;CCLE	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	P14416	DRD2	P17252	PRKCA	S359	R361W	361	Missense	proximal	2	no	22.387	16.947	EPSD	GDSC;CCLE	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	P49685	GPR15	P17252	PRKCA	S357	A351D	351	Missense	distal	-6	no	17.197	17.150	PhosphoSitePlus	GDSC;CCLE	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	P22460	KCNA5	P17252	PRKCA	S414	L420M	420	Missense	distal	6	no	17.936	17.946	EPSD	GDSC;CCLE	16.704	Up-regulation
AGC_PKC_PKCa_PRKCA_ST	P22460	KCNA5	P17252	PRKCA	S414	L413P	413	Missense	proximal	-1	no	17.936	18.056	EPSD	GDSC	16.704	Up-regulation
AGC_PKC_PKCa_PRKCA_ST	P22460	KCNA5	P17252	PRKCA	S417	L420M	420	Missense	distal	3	no	17.099	18.069	EPSD	GDSC;CCLE	16.704	Up-regulation
AGC_PKC_PKCa_PRKCA_ST	P22460	KCNA5	P17252	PRKCA	S417	L413P	413	Missense	distal	-4	no	17.099	17.359	EPSD	GDSC	16.704	Up-regulation
AGC_PKC_PKCa_PRKCA_ST	P22460	KCNA5	P17252	PRKCA	S430	M431T	431	Missense	proximal	1	no	17.446	17.161	EPSD	GDSC;CCLE	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	P22460	KCNA5	P17252	PRKCA	S430	A429V	429	Missense	proximal	-1	no	17.446	16.543	EPSD	GDSC;CCLE	16.704	Loss
AGC_PKC_PKCa_PRKCA_ST	P22460	KCNA5	P17252	PRKCA	S557	S557R	557	Missense	central	0	yes	17.842	0.000	EPSD	GDSC;CCLE	16.704	Loss
TK_Src_SRM_Y	Q13882	PTK6	Q9H3Y6	SRMS	Y61	A56G	56	Missense	distal	-5	no	1.564	1.767	EPSD	GDSC	1.179	Up-regulation
TK_Src_SRM_Y	Q13882	PTK6	Q9H3Y6	SRMS	Y66	E69K	69	Missense	distal	3	no	2.496	1.804	EPSD	GDSC	1.179	Down-regulation
CAMK_CAMKL_BRSK_BRSK1_ST	P23258	TUBG1	Q8TDC3	BRSK1	S131	S131I	131	Missense	central	0	yes	1.301	0.000	PhosphoSitePlus;EPSD	GDSC;CCLE	0.579	Loss
Other_IKK_IKBKB_ST	Q99704	DOK1	O14920	IKBKB	S302	I305L	305	Missense	distal	3	no	20.031	21.978	EPSD	GDSC;CCLE	16.613	Up-regulation
Other_IKK_IKBKB_ST	Q99704	DOK1	O14920	IKBKB	S302	R304C	304	Missense	proximal	2	no	20.031	19.827	EPSD	GDSC;CCLE	16.613	Down-regulation
Other_IKK_IKBKB_ST	Q99704	DOK1	O14920	IKBKB	S302	R304H	304	Missense	proximal	2	no	20.031	20.009	EPSD	GDSC;CCLE	16.613	Down-regulation
Other_IKK_IKBKB_ST	Q04206	RELA	O14920	IKBKB	S261	D259G	259	Missense	proximal	-2	no	17.978	19.093	EPSD;PhosphoSitePlus	GDSC;CCLE	16.613	Up-regulation
Other_IKK_IKBKB_ST	Q04206	RELA	O14920	IKBKB	S261	A258T	258	Missense	distal	-3	no	17.978	17.926	EPSD;PhosphoSitePlus	GDSC;CCLE	16.613	Down-regulation
Other_IKK_IKBKB_ST	P25963	NFKBIA	O14920	IKBKB	S283	L277P	277	Missense	distal	-6	no	17.052	17.427	EPSD	GDSC	16.613	Up-regulation
Other_IKK_IKBKB_ST	Q14653	IRF3	O14920	IKBKB	S396	T390A	390	Missense	distal	-6	no	28.361	28.506	EPSD;PhosphoSitePlus	GDSC;CCLE	16.613	Up-regulation
Other_IKK_IKBKB_ST	P01100	FOS	O14920	IKBKB	S258	S260G	260	Missense	proximal	2	no	25.711	25.074	EPSD	GDSC;CCLE	16.613	Down-regulation
Other_IKK_IKBKB_ST	P01100	FOS	O14920	IKBKB	S261	S260G	260	Missense	proximal	-1	no	23.494	23.883	EPSD	GDSC;CCLE	16.613	Up-regulation
Other_IKK_IKBKB_ST	P01100	FOS	O14920	IKBKB	S362	R359C	359	Missense	distal	-3	no	19.817	19.236	EPSD	GDSC;CCLE	16.613	Down-regulation
Other_IKK_IKBKB_ST	P01100	FOS	O14920	IKBKB	S362	R359H	359	Missense	distal	-3	no	19.817	19.523	EPSD	GDSC;CCLE	16.613	Down-regulation
Other_IKK_IKBKB_ST	P01100	FOS	O14920	IKBKB	S364	R359C	359	Missense	distal	-5	no	24.792	24.580	EPSD	GDSC;CCLE	16.613	Down-regulation
Other_IKK_IKBKB_ST	P01100	FOS	O14920	IKBKB	S364	R359H	359	Missense	distal	-5	no	24.792	24.878	EPSD	GDSC;CCLE	16.613	Up-regulation
Other_IKK_IKBKB_ST	Q01201	RELB	O14920	IKBKB	S41	S42L	42	Missense	proximal	1	no	21.787	22.557	EPSD	GDSC;CCLE	16.613	Up-regulation
Other_IKK_IKBKB_ST	Q01201	RELB	O14920	IKBKB	S48	S42L	42	Missense	distal	-6	no	23.926	23.291	EPSD	GDSC;CCLE	16.613	Down-regulation
Other_IKK_IKBKB_ST	Q01201	RELB	O14920	IKBKB	S151	S156R	156	Missense	distal	5	no	19.299	18.201	EPSD	GDSC;CCLE	16.613	Down-regulation
Other_IKK_IKBKB_ST	Q92574	TSC1	O14920	IKBKB	S108	P111A	111	Missense	distal	3	no	21.638	21.531	EPSD	GDSC;CCLE	16.613	Down-regulation
Other_IKK_IKBKB_ST	Q92574	TSC1	O14920	IKBKB	S348	A344S	344	Missense	distal	-4	no	13.113	17.255	EPSD	GDSC	16.613	Gain
Other_IKK_IKBKB_ST	Q92574	TSC1	O14920	IKBKB	S1116	L1121M	1121	Missense	distal	5	no	23.988	26.890	EPSD	GDSC;CCLE	16.613	Up-regulation
Other_IKK_IKBKB_ST	Q92574	TSC1	O14920	IKBKB	S1147	P1143T	1143	Missense	distal	-4	no	19.020	18.843	EPSD	GDSC	16.613	Down-regulation
Other_IKK_IKBKB_ST	Q92574	TSC1	O14920	IKBKB	S1147	P1142H	1142	Missense	distal	-5	no	19.020	19.044	EPSD	GDSC	16.613	Up-regulation
Other_IKK_IKBKB_ST	O95999	BCL10	O14920	IKBKB	S134	T130M	130	Missense	distal	-4	no	20.709	24.936	EPSD;PhosphoSitePlus	GDSC;CCLE	16.613	Up-regulation
Other_IKK_IKBKB_ST	O95999	BCL10	O14920	IKBKB	S136	T130M	130	Missense	distal	-6	no	32.835	33.264	EPSD;PhosphoSitePlus	GDSC;CCLE	16.613	Up-regulation
Other_IKK_IKBKB_ST	O95999	BCL10	O14920	IKBKB	S167	T163A	163	Missense	distal	-4	no	16.643	16.201	EPSD	GDSC;CCLE	16.613	Loss
Other_IKK_IKBKB_ST	O95999	BCL10	O14920	IKBKB	S170	T163A	163	Missense	distal	-7	no	16.668	17.099	EPSD	GDSC;CCLE	16.613	Up-regulation
Other_IKK_IKBKB_ST	P42858	HTT	O14920	IKBKB	S415	R416C	416	Missense	proximal	1	no	25.554	26.292	EPSD	GDSC;CCLE	16.613	Up-regulation
Other_IKK_IKBKB_ST	P42858	HTT	O14920	IKBKB	S415	R414*	414	Missense	proximal	-1	no	25.554	25.764	EPSD	GDSC	16.613	Up-regulation
Other_IKK_IKBKB_ST	P42858	HTT	O14920	IKBKB	S419	R416C	416	Missense	distal	-3	no	17.051	16.471	EPSD	GDSC;CCLE	16.613	Loss
Other_IKK_IKBKB_ST	P42858	HTT	O14920	IKBKB	S419	R414*	414	Missense	distal	-5	no	17.051	16.793	EPSD	GDSC	16.613	Down-regulation
Other_IKK_IKBKB_ST	P42858	HTT	O14920	IKBKB	S459	S457L	457	Missense	proximal	-2	no	21.565	22.336	EPSD	GDSC	16.613	Up-regulation
Other_IKK_IKBKB_ST	P42858	HTT	O14920	IKBKB	S1179	L1178V	1178	Missense	proximal	-1	no	17.540	17.954	EPSD	GDSC;CCLE	16.613	Up-regulation
Other_IKK_IKBKB_ST	P42858	HTT	O14920	IKBKB	S2074	P2081Q	2081	Missense	distal	7	no	18.883	19.379	EPSD	GDSC;CCLE	16.613	Up-regulation
Other_IKK_IKBKB_ST	P42858	HTT	O14920	IKBKB	S2340	E2341K	2341	Missense	proximal	1	no	19.326	17.052	EPSD	GDSC;CCLE	16.613	Down-regulation
Other_IKK_IKBKB_ST	P42858	HTT	O14920	IKBKB	S2340	K2337R	2337	Missense	distal	-3	no	19.326	19.056	EPSD	GDSC	16.613	Down-regulation
Other_IKK_IKBKB_ST	P42858	HTT	O14920	IKBKB	S2651	A2648E	2648	Missense	distal	-3	no	16.872	16.779	EPSD	GDSC;CCLE	16.613	Down-regulation
Other_IKK_IKBKB_ST	P42858	HTT	O14920	IKBKB	S2655	A2648E	2648	Missense	distal	-7	no	21.289	21.321	EPSD	GDSC;CCLE	16.613	Up-regulation
Other_IKK_IKBKB_ST	P19438	TNFRSF1A	O14920	IKBKB	S381	E384D	384	Missense	distal	3	no	17.341	16.710	PhosphoSitePlus	GDSC;CCLE	16.613	Down-regulation
Other_IKK_IKBKB_ST	Q6P2E9	EDC4	O14920	IKBKB	S734	S729Y	729	Missense	distal	-5	no	18.167	17.838	EPSD	GDSC;CCLE	16.613	Down-regulation
Other_IKK_IKBKB_ST	Q6P2E9	EDC4	O14920	IKBKB	S734	S729F	729	Missense	distal	-5	no	18.167	17.929	EPSD	GDSC;CCLE	16.613	Down-regulation
Other_IKK_IKBKB_ST	Q6P2E9	EDC4	O14920	IKBKB	S735	S729Y	729	Missense	distal	-6	no	18.217	16.871	EPSD	GDSC;CCLE	16.613	Down-regulation
Other_IKK_IKBKB_ST	Q6P2E9	EDC4	O14920	IKBKB	S735	S729F	729	Missense	distal	-6	no	18.217	17.068	EPSD	GDSC;CCLE	16.613	Down-regulation
Other_IKK_IKBKB_ST	Q6P2E9	EDC4	O14920	IKBKB	S809	A814S	814	Missense	distal	5	no	17.684	17.369	EPSD	GDSC;CCLE	16.613	Down-regulation
Other_IKK_IKBKB_ST	Q6P2E9	EDC4	O14920	IKBKB	S875	A876V	876	Missense	proximal	1	no	16.316	16.655	EPSD	GDSC;CCLE	16.613	Gain
Other_IKK_IKBKB_ST	Q6P2E9	EDC4	O14920	IKBKB	S879	A876V	876	Missense	distal	-3	no	17.167	16.708	EPSD	GDSC;CCLE	16.613	Down-regulation
Other_IKK_IKBKB_ST	Q6P2E9	EDC4	O14920	IKBKB	S918	K922N	922	Missense	distal	4	no	16.950	15.007	EPSD	GDSC;CCLE	16.613	Loss
Other_IKK_IKBKB_ST	Q6P2E9	EDC4	O14920	IKBKB	S918	S918L	918	Missense	central	0	yes	16.950	0.000	EPSD	GDSC	16.613	Loss
Other_IKK_IKBKB_ST	Q6P2E9	EDC4	O14920	IKBKB	S936	E940*	940	Missense	distal	4	no	19.893	14.781	EPSD	GDSC	16.613	Loss
Other_IKK_IKBKB_ST	Q6P2E9	EDC4	O14920	IKBKB	S1058	L1059R	1059	Missense	proximal	1	no	19.010	18.632	EPSD	GDSC	16.613	Down-regulation
Other_IKK_IKBKB_ST	Q6P2E9	EDC4	O14920	IKBKB	S1058	G1064A	1064	Missense	distal	6	no	19.010	18.547	EPSD	GDSC;CCLE	16.613	Down-regulation
Other_IKK_IKBKB_ST	Q6P2E9	EDC4	O14920	IKBKB	S1069	L1066M	1066	Missense	distal	-3	no	21.398	21.977	EPSD	GDSC;CCLE	16.613	Up-regulation
Other_IKK_IKBKB_ST	Q6P2E9	EDC4	O14920	IKBKB	S1069	G1064A	1064	Missense	distal	-5	no	21.398	21.495	EPSD	GDSC;CCLE	16.613	Up-regulation
Other_IKK_IKBKB_ST	Q6P2E9	EDC4	O14920	IKBKB	S1158	R1162W	1162	Missense	distal	4	no	26.098	20.351	EPSD	GDSC;CCLE	16.613	Down-regulation
Other_IKK_IKBKB_ST	P21580	TNFAIP3	O14920	IKBKB	S550	A545V	545	Missense	distal	-5	no	22.636	22.288	EPSD	GDSC	16.613	Down-regulation
Other_IKK_IKBKB_ST	P21580	TNFAIP3	O14920	IKBKB	S573	R569P	569	Missense	distal	-4	no	20.858	19.645	EPSD	GDSC;CCLE	16.613	Down-regulation
Other_IKK_IKBKB_ST	P21580	TNFAIP3	O14920	IKBKB	S573	R569W	569	Missense	distal	-4	no	20.858	11.817	EPSD	GDSC;CCLE	16.613	Loss
Other_IKK_IKBKB_ST	Q9Y4G8	RAPGEF2	O14920	IKBKB	S592	F599V	599	Missense	distal	7	no	18.810	18.561	EPSD	GDSC;CCLE	16.613	Down-regulation
Other_IKK_IKBKB_ST	Q9Y4G8	RAPGEF2	O14920	IKBKB	S1223	S1225N	1225	Missense	proximal	2	no	23.614	23.580	EPSD	GDSC;CCLE	16.613	Down-regulation
Other_IKK_IKBKB_ST	P35568	IRS1	O14920	IKBKB	S270	R267C	267	Missense	distal	-3	no	16.872	16.292	EPSD	GDSC;CCLE	16.613	Loss
Other_IKK_IKBKB_ST	P35568	IRS1	O14920	IKBKB	S274	R267C	267	Missense	distal	-7	no	20.210	18.393	EPSD	GDSC;CCLE	16.613	Down-regulation
Other_IKK_IKBKB_ST	P35568	IRS1	O14920	IKBKB	S380	R381C	381	Missense	proximal	1	no	18.081	18.819	EPSD	GDSC;CCLE	16.613	Up-regulation
Other_IKK_IKBKB_ST	P35568	IRS1	O14920	IKBKB	S380	A386S	386	Missense	distal	6	no	18.081	16.866	EPSD	GDSC;CCLE	16.613	Down-regulation
Other_IKK_IKBKB_ST	P35568	IRS1	O14920	IKBKB	S380	P376L	376	Missense	distal	-4	no	18.081	14.972	EPSD	GDSC;CCLE	16.613	Loss
Other_IKK_IKBKB_ST	P35568	IRS1	O14920	IKBKB	S547	A546V	546	Missense	proximal	-1	no	16.227	16.645	EPSD	GDSC;CCLE	16.613	Gain
Other_IKK_IKBKB_ST	P35568	IRS1	O14920	IKBKB	S853	R854C	854	Missense	proximal	1	no	16.533	17.271	EPSD	GDSC	16.613	Gain
Other_IKK_IKBKB_ST	P35568	IRS1	O14920	IKBKB	S869	L871F	871	Missense	proximal	2	no	19.349	19.251	EPSD	GDSC;CCLE	16.613	Down-regulation
Other_IKK_IKBKB_ST	P35568	IRS1	O14920	IKBKB	S1078	S1084R	1084	Missense	distal	6	no	20.834	21.458	EPSD	GDSC	16.613	Up-regulation
Other_IKK_IKBKB_ST	P35568	IRS1	O14920	IKBKB	S1078	A1085D	1085	Missense	distal	7	no	20.834	20.166	EPSD	GDSC;CCLE	16.613	Down-regulation
Other_IKK_IKBKB_ST	P35568	IRS1	O14920	IKBKB	S1213	S1218P	1218	Missense	distal	5	no	24.941	24.740	EPSD	GDSC	16.613	Down-regulation
Other_IKK_IKBKB_ST	P35568	IRS1	O14920	IKBKB	S1216	S1218P	1218	Missense	proximal	2	no	20.156	19.899	EPSD	GDSC	16.613	Down-regulation
Other_IKK_IKBKB_ST	P35568	IRS1	O14920	IKBKB	T1219	S1218P	1218	Missense	proximal	-1	no	16.616	16.619	EPSD	GDSC	16.613	Up-regulation
Other_IKK_IKBKB_ST	P35568	IRS1	O14920	IKBKB	S1222	S1218P	1218	Missense	distal	-4	no	28.475	24.952	EPSD	GDSC	16.613	Down-regulation
Other_IKK_IKBKB_ST	P35568	IRS1	O14920	IKBKB	S1223	S1218P	1218	Missense	distal	-5	no	16.694	16.727	EPSD	GDSC	16.613	Up-regulation
Other_IKK_IKBKB_ST	P35568	IRS1	O14920	IKBKB	S1227	S1233N	1233	Missense	distal	6	no	23.038	24.445	EPSD	GDSC;CCLE	16.613	Up-regulation
Other_IKK_IKBKB_ST	P35568	IRS1	O14920	IKBKB	S1231	S1233N	1233	Missense	proximal	2	no	27.300	27.266	EPSD	GDSC;CCLE	16.613	Down-regulation
Other_IKK_IKBKB_ST	Q7Z434	MAVS	O14920	IKBKB	S263	A264V	264	Missense	proximal	1	no	20.310	20.649	EPSD	GDSC;CCLE	16.613	Up-regulation
Other_IKK_IKBKB_ST	Q7Z434	MAVS	O14920	IKBKB	S416	S416L	416	Missense	central	0	yes	25.672	0.000	EPSD	GDSC;CCLE	16.613	Loss
Other_IKK_IKBKB_ST	Q16875	PFKFB3	O14920	IKBKB	S478	R475H	475	Missense	distal	-3	no	17.623	17.329	EPSD	GDSC;CCLE	16.613	Down-regulation
Other_IKK_IKBKB_ST	P20749	BCL3	O14920	IKBKB	S402	S404C	404	Missense	proximal	2	no	16.899	16.590	EPSD	GDSC;CCLE	16.613	Loss
Other_IKK_IKBKB_ST	P20749	BCL3	O14920	IKBKB	S402	A397T	397	Missense	distal	-5	no	16.899	16.965	EPSD	GDSC	16.613	Up-regulation
Other_IKK_IKBKB_ST	P23396	RPS3	O14920	IKBKB	S139	R143Q	143	Missense	distal	4	no	16.180	18.174	EPSD	GDSC;CCLE	16.613	Gain
Other_IKK_IKBKB_ST	P23396	RPS3	O14920	IKBKB	S209	P213L	213	Missense	distal	4	no	19.767	20.122	PhosphoSitePlus	GDSC;CCLE	16.613	Up-regulation
Other_IKK_IKBKB_ST	P23396	RPS3	O14920	IKBKB	S209	D215V	215	Missense	distal	6	no	19.767	21.014	PhosphoSitePlus	GDSC;CCLE	16.613	Up-regulation
Other_IKK_IKBKB_ST	Q96CV9	OPTN	O14920	IKBKB	S162	N169T	169	Missense	distal	7	no	22.256	22.380	EPSD	GDSC;CCLE	16.613	Up-regulation
Other_IKK_IKBKB_ST	Q96CV9	OPTN	O14920	IKBKB	S162	L166V	166	Missense	distal	4	no	22.256	18.859	EPSD	GDSC;CCLE	16.613	Down-regulation
Other_IKK_IKBKB_ST	Q96CV9	OPTN	O14920	IKBKB	S171	N169T	169	Missense	proximal	-2	no	18.566	18.422	EPSD	GDSC;CCLE	16.613	Down-regulation
Other_IKK_IKBKB_ST	Q96CV9	OPTN	O14920	IKBKB	S171	L166V	166	Missense	distal	-5	no	18.566	18.243	EPSD	GDSC;CCLE	16.613	Down-regulation
Other_IKK_IKBKB_ST	Q96CV9	OPTN	O14920	IKBKB	S173	N169T	169	Missense	distal	-4	no	16.933	16.938	EPSD	GDSC;CCLE	16.613	Up-regulation
Other_IKK_IKBKB_ST	Q96CV9	OPTN	O14920	IKBKB	S173	L166V	166	Missense	distal	-7	no	16.933	15.897	EPSD	GDSC;CCLE	16.613	Loss
Other_IKK_IKBKB_ST	Q96CV9	OPTN	O14920	IKBKB	S191	E187Q	187	Missense	distal	-4	no	17.322	12.459	EPSD	GDSC;CCLE	16.613	Loss
Other_IKK_IKBKB_ST	Q96CV9	OPTN	O14920	IKBKB	S234	H228Y	228	Missense	distal	-6	no	20.993	19.759	EPSD	GDSC;CCLE	16.613	Down-regulation
Other_IKK_IKBKB_ST	Q96CV9	OPTN	O14920	IKBKB	S269	S269R	269	Missense	central	0	yes	28.400	0.000	EPSD	GDSC;CCLE	16.613	Loss
Other_IKK_IKBKB_ST	Q96CV9	OPTN	O14920	IKBKB	S346	Q352P	352	Missense	distal	6	no	33.424	33.773	EPSD	GDSC;CCLE	16.613	Up-regulation
Other_IKK_IKBKB_ST	Q96CV9	OPTN	O14920	IKBKB	S513	E516Q	516	Missense	distal	3	no	22.426	19.519	PhosphoSitePlus	GDSC;CCLE	16.613	Down-regulation
Other_IKK_IKBKB_ST	O00161	SNAP23	O14920	IKBKB	S95	K100N	100	Missense	distal	5	no	26.937	22.951	PhosphoSitePlus	GDSC;CCLE	16.613	Down-regulation
Other_IKK_IKBKB_ST	O43524	FOXO3	O14920	IKBKB	S200	F194L	194	Missense	distal	-6	no	16.770	17.284	EPSD	GDSC;CCLE	16.613	Up-regulation
Other_IKK_IKBKB_ST	O43524	FOXO3	O14920	IKBKB	S280	Q275*	275	Missense	distal	-5	no	23.144	23.393	EPSD	GDSC	16.613	Up-regulation
Other_IKK_IKBKB_ST	O43524	FOXO3	O14920	IKBKB	S321	V320I	320	Missense	proximal	-1	no	17.349	17.713	EPSD	GDSC;CCLE	16.613	Up-regulation
Other_IKK_IKBKB_ST	O43524	FOXO3	O14920	IKBKB	S555	E561D	561	Missense	distal	6	no	18.413	17.751	EPSD	GDSC	16.613	Down-regulation
Other_IKK_IKBKB_ST	O43524	FOXO3	O14920	IKBKB	S564	E561D	561	Missense	distal	-3	no	18.329	18.037	EPSD	GDSC	16.613	Down-regulation
Other_IKK_IKBKB_ST	O43524	FOXO3	O14920	IKBKB	S644	D643H	643	Missense	proximal	-1	no	22.630	22.407	PhosphoSitePlus	GDSC	16.613	Down-regulation
Other_IKK_IKBKB_ST	Q04864	REL	O14920	IKBKB	S526	V527A	527	Missense	proximal	1	no	17.352	17.013	EPSD	GDSC;CCLE	16.613	Down-regulation
CAMK_MAPKAPK_MNK_MKNK1_ST	P23246	SFPQ	Q9BUB5	MKNK1	S283	E290D	290	Missense	distal	7	no	14.701	14.698	PhosphoSitePlus;EPSD	GDSC;CCLE	8.316	Down-regulation
Other_Aur_AurB_ST	P38159	RBMX	Q96GD4	AURKB	S165	S165C	165	Missense	central	0	yes	0.020	0.000	EPSD	GDSC	0.010	Loss
Other_Aur_AurB_ST	P38159	RBMX	Q96GD4	AURKB	S174	R172L	172	Missense	proximal	-2	no	0.073	0.003	EPSD	GDSC;CCLE	0.010	Loss
Other_Aur_AurB_ST	P38159	RBMX	Q96GD4	AURKB	S219	Y214*	214	Missense	distal	-5	no	0.013	0.012	EPSD	GDSC	0.010	Down-regulation
Other_Aur_AurB_ST	P38159	RBMX	Q96GD4	AURKB	S326	R324Q	324	Missense	proximal	-2	no	0.074	0.000	PhosphoSitePlus	GDSC	0.010	Loss
Other_Aur_AurB_ST	Q9NQS7	INCENP	Q96GD4	AURKB	S336	A335T	335	Missense	proximal	-1	no	0.078	0.077	EPSD	GDSC	0.010	Down-regulation
Other_Aur_AurB_ST	Q9NQS7	INCENP	Q96GD4	AURKB	S336	R338K	338	Missense	proximal	2	no	0.078	0.077	EPSD	GDSC;CCLE	0.010	Down-regulation
Other_Aur_AurB_ST	Q9NQS7	INCENP	Q96GD4	AURKB	T343	R338K	338	Missense	distal	-5	no	0.013	0.012	EPSD	GDSC;CCLE	0.010	Down-regulation
Other_Aur_AurB_ST	Q9NQS7	INCENP	Q96GD4	AURKB	T524	K521N	521	Missense	distal	-3	no	0.072	0.071	EPSD	GDSC;CCLE	0.010	Down-regulation
Other_Aur_AurB_ST	Q14980	NUMA1	Q96GD4	AURKB	S633	D632N	632	Missense	proximal	-1	no	0.073	0.074	EPSD	GDSC	0.010	Up-regulation
Other_Aur_AurB_ST	Q14980	NUMA1	Q96GD4	AURKB	S1287	R1286H	1286	Missense	proximal	-1	no	0.010	0.002	EPSD	GDSC;CCLE	0.010	Loss
Other_Aur_AurB_ST	Q14980	NUMA1	Q96GD4	AURKB	S1288	R1286H	1286	Missense	proximal	-2	no	0.070	0.000	EPSD	GDSC;CCLE	0.010	Loss
Other_Aur_AurB_ST	Q14980	NUMA1	Q96GD4	AURKB	S1432	R1427W	1427	Missense	distal	-5	no	0.013	0.011	EPSD	GDSC;CCLE	0.010	Down-regulation
Other_Aur_AurB_ST	Q14980	NUMA1	Q96GD4	AURKB	S1840	R1839W	1839	Missense	proximal	-1	no	0.011	0.004	EPSD	GDSC;CCLE	0.010	Loss
Other_Aur_AurB_ST	Q14980	NUMA1	Q96GD4	AURKB	T1879	R1877H	1877	Missense	proximal	-2	no	0.064	-0.006	EPSD	GDSC;CCLE	0.010	Loss
Other_Aur_AurB_ST	Q14980	NUMA1	Q96GD4	AURKB	S1882	R1877H	1877	Missense	distal	-5	no	0.014	0.012	EPSD	GDSC;CCLE	0.010	Down-regulation
Other_Aur_AurB_ST	Q14980	NUMA1	Q96GD4	AURKB	S1883	R1877H	1877	Missense	distal	-6	no	0.072	0.071	EPSD	GDSC;CCLE	0.010	Down-regulation
Other_Aur_AurB_ST	Q14980	NUMA1	Q96GD4	AURKB	T2007	R2012C	2012	Missense	distal	5	no	0.008	0.010	EPSD	GDSC	0.010	Gain
Other_Aur_AurB_ST	Q14980	NUMA1	Q96GD4	AURKB	S2077	S2077P	2077	Missense	central	0	yes	0.010	0.000	EPSD	GDSC	0.010	Loss
Other_Aur_AurB_ST	Q14980	NUMA1	Q96GD4	AURKB	S2077	S2082R	2082	Missense	distal	5	no	0.010	0.008	EPSD	GDSC	0.010	Loss
Other_Aur_AurB_ST	Q14980	NUMA1	Q96GD4	AURKB	S2077	S2077Y	2077	Missense	central	0	yes	0.010	0.000	EPSD	GDSC	0.010	Loss
Other_Aur_AurB_ST	Q14980	NUMA1	Q96GD4	AURKB	T2084	S2082R	2082	Missense	proximal	-2	no	-0.001	0.072	EPSD	GDSC	0.010	Gain
Other_Aur_AurB_ST	Q14980	NUMA1	Q96GD4	AURKB	S2087	T2092P	2092	Missense	distal	5	no	0.078	0.079	EPSD	GDSC	0.010	Up-regulation
Other_Aur_AurB_ST	Q14980	NUMA1	Q96GD4	AURKB	S2087	S2082R	2082	Missense	distal	-5	no	0.078	0.080	EPSD	GDSC	0.010	Up-regulation
Other_Aur_AurB_ST	O14777	NDC80	Q96GD4	AURKB	T49	K53R	53	Missense	distal	4	no	0.010	0.011	PhosphoSitePlus;EPSD	GDSC;CCLE	0.010	Up-regulation
Other_Aur_AurB_ST	O14777	NDC80	Q96GD4	AURKB	S55	K53R	53	Missense	proximal	-2	no	0.017	0.076	EPSD;PhosphoSitePlus	GDSC;CCLE	0.010	Up-regulation
Other_Aur_AurB_ST	Q8NEM2	SHCBP1	Q96GD4	AURKB	S96	S96F	96	Missense	central	0	yes	0.011	0.000	EPSD	GDSC;CCLE	0.010	Loss
Other_Aur_AurB_ST	P06400	RB1	Q96GD4	AURKB	S82	S82*	82	Missense	central	0	yes	0.011	0.000	EPSD	GDSC	0.010	Loss
Other_Aur_AurB_ST	Q12888	TP53BP1	Q96GD4	AURKB	T1409	R1403C	1403	Missense	distal	-6	no	0.071	0.069	EPSD	GDSC	0.010	Down-regulation
Other_Aur_AurB_ST	Q53HL2	CDCA8	Q96GD4	AURKB	T152	R151I	151	Missense	proximal	-1	no	0.019	0.011	EPSD	GDSC;CCLE	0.010	Down-regulation
Other_Aur_AurB_ST	O00571	DDX3X	Q96GD4	AURKB	S290	R292G	292	Missense	proximal	2	no	0.017	0.016	EPSD	GDSC;CCLE	0.010	Down-regulation
Other_Aur_AurB_ST	Q99661	KIF2C	Q96GD4	AURKB	S192	S192L	192	Missense	central	0	yes	0.078	0.000	PhosphoSitePlus;EPSD	GDSC;CCLE	0.010	Loss
Other_Aur_AurB_ST	P14136	GFAP	Q96GD4	AURKB	T7	R12H	12	Missense	distal	5	no	0.076	0.078	EPSD;PhosphoSitePlus	GDSC;CCLE	0.010	Up-regulation
Other_Aur_AurB_ST	P14136	GFAP	Q96GD4	AURKB	S13	R12H	12	Missense	proximal	-1	no	0.078	0.071	EPSD;PhosphoSitePlus	GDSC;CCLE	0.010	Down-regulation
Other_Aur_AurB_ST	P05787	KRT8	Q96GD4	AURKB	S134	A132T	132	Missense	proximal	-2	no	0.011	0.012	EPSD	GDSC;CCLE	0.010	Up-regulation
Other_Aur_AurB_ST	P05787	KRT8	Q96GD4	AURKB	T416	T416A	416	Missense	central	0	yes	0.010	0.000	EPSD	GDSC;CCLE	0.010	Loss
Other_Aur_AurB_ST	P05787	KRT8	Q96GD4	AURKB	T416	G421A	421	Missense	distal	5	no	0.010	0.009	EPSD	GDSC	0.010	Loss
Other_Aur_AurB_ST	P04637	TP53	Q96GD4	AURKB	S183	S183*	183	Missense	central	0	yes	0.073	0.000	EPSD;PhosphoSitePlus	GDSC	0.010	Loss
Other_Aur_AurB_ST	P04637	TP53	Q96GD4	AURKB	S183	E180*	180	Missense	distal	-3	no	0.073	0.072	EPSD;PhosphoSitePlus	GDSC	0.010	Down-regulation
Other_Aur_AurB_ST	P04637	TP53	Q96GD4	AURKB	T211	R209*	209	Missense	proximal	-2	no	0.069	-0.003	EPSD;PhosphoSitePlus	GDSC	0.010	Loss
Other_Aur_AurB_ST	P04637	TP53	Q96GD4	AURKB	S215	R213*	213	Missense	proximal	-2	no	0.072	0.000	EPSD;PhosphoSitePlus	GDSC	0.010	Loss
Other_Aur_AurB_ST	P04637	TP53	Q96GD4	AURKB	S215	R209*	209	Missense	distal	-6	no	0.072	0.070	EPSD;PhosphoSitePlus	GDSC	0.010	Down-regulation
Other_Aur_AurB_ST	Q9BQG0	MYBBP1A	Q96GD4	AURKB	S635	R634W	634	Missense	proximal	-1	no	0.076	0.069	EPSD	GDSC	0.010	Down-regulation
Other_Aur_AurB_ST	Q9BQG0	MYBBP1A	Q96GD4	AURKB	S635	R636H	636	Missense	proximal	1	no	0.076	0.077	EPSD	GDSC;CCLE	0.010	Up-regulation
Other_Aur_AurB_ST	Q9BQG0	MYBBP1A	Q96GD4	AURKB	T637	R634W	634	Missense	distal	-3	no	0.011	0.005	EPSD	GDSC	0.010	Loss
Other_Aur_AurB_ST	Q9BQG0	MYBBP1A	Q96GD4	AURKB	T637	R636H	636	Missense	proximal	-1	no	0.011	0.004	EPSD	GDSC;CCLE	0.010	Loss
Other_Aur_AurB_ST	Q9BQG0	MYBBP1A	Q96GD4	AURKB	S1241	T1239A	1239	Missense	proximal	-2	no	0.010	0.009	EPSD	GDSC;CCLE	0.010	Loss
Other_Aur_AurB_ST	Q9BQG0	MYBBP1A	Q96GD4	AURKB	S1303	R1297W	1297	Missense	distal	-6	no	0.073	0.072	PhosphoSitePlus	GDSC	0.010	Down-regulation
Other_Aur_AurB_ST	Q8TF76	HASPIN	Q96GD4	AURKB	S620	S620P	620	Missense	central	0	yes	0.011	0.000	EPSD	GDSC	0.010	Loss
Other_Aur_AurB_ST	Q8TF76	HASPIN	Q96GD4	AURKB	S620	R616*	616	Missense	distal	-4	no	0.011	0.010	EPSD	GDSC	0.010	Down-regulation
Other_Aur_AurB_ST	O95239	KIF4A	Q96GD4	AURKB	S894	T893P	893	Missense	proximal	-1	no	0.013	0.012	EPSD	GDSC;CCLE	0.010	Down-regulation
Other_Aur_AurB_ST	O95239	KIF4A	Q96GD4	AURKB	T1010	H1005R	1005	Missense	distal	-5	no	0.011	0.012	EPSD	GDSC	0.010	Up-regulation
Other_Aur_AurB_ST	Q8NEY8	PPHLN1	Q96GD4	AURKB	T396	R394P	394	Missense	proximal	-2	no	0.076	0.001	EPSD	GDSC	0.010	Loss
Other_Aur_AurB_ST	Q8NEY8	PPHLN1	Q96GD4	AURKB	T396	R400P	400	Missense	distal	4	no	0.076	0.075	EPSD	GDSC;CCLE	0.010	Down-regulation
Other_Aur_AurB_ST	Q8NEY8	PPHLN1	Q96GD4	AURKB	T397	R394P	394	Missense	distal	-3	no	0.080	0.072	EPSD	GDSC	0.010	Down-regulation
Other_Aur_AurB_ST	Q8NEY8	PPHLN1	Q96GD4	AURKB	T403	R400P	400	Missense	distal	-3	no	0.076	0.069	EPSD	GDSC;CCLE	0.010	Down-regulation
Other_Aur_AurB_ST	Q5UIP0	RIF1	Q96GD4	AURKB	S111	R116C	116	Missense	distal	5	no	0.010	0.012	EPSD	GDSC	0.010	Up-regulation
Other_Aur_AurB_ST	Q5UIP0	RIF1	Q96GD4	AURKB	S1184	S1189P	1189	Missense	distal	5	no	0.020	0.021	EPSD	GDSC;CCLE	0.010	Up-regulation
Other_Aur_AurB_ST	Q5UIP0	RIF1	Q96GD4	AURKB	S1417	R1420*	1420	Missense	distal	3	no	0.074	0.075	EPSD	GDSC	0.010	Up-regulation
Other_Aur_AurB_ST	Q5UIP0	RIF1	Q96GD4	AURKB	S1418	R1419W	1419	Missense	proximal	1	no	0.074	0.075	EPSD	GDSC;CCLE	0.010	Up-regulation
Other_Aur_AurB_ST	Q5UIP0	RIF1	Q96GD4	AURKB	S1422	R1419W	1419	Missense	distal	-3	no	0.086	0.079	EPSD	GDSC;CCLE	0.010	Down-regulation
Other_Aur_AurB_ST	Q5UIP0	RIF1	Q96GD4	AURKB	S1422	R1420*	1420	Missense	proximal	-2	no	0.086	0.014	EPSD	GDSC	0.010	Down-regulation
Other_Aur_AurB_ST	Q5UIP0	RIF1	Q96GD4	AURKB	S1688	R1686*	1686	Missense	proximal	-2	no	0.073	0.002	EPSD	GDSC	0.010	Loss
Other_Aur_AurB_ST	O14950	MYL12B	Q96GD4	AURKB	T19	R14H	14	Missense	distal	-5	no	0.068	0.066	EPSD	GDSC;CCLE	0.010	Down-regulation
Other_Aur_AurB_ST	O14950	MYL12B	Q96GD4	AURKB	S20	R14H	14	Missense	distal	-6	no	0.012	0.011	PhosphoSitePlus	GDSC;CCLE	0.010	Down-regulation
Other_Aur_AurB_ST	Q8TEW0	PARD3	Q96GD4	AURKB	S174	R172H	172	Missense	proximal	-2	no	0.072	0.001	EPSD	GDSC;CCLE	0.010	Loss
Other_Aur_AurB_ST	Q8TEW0	PARD3	Q96GD4	AURKB	T901	E899K	899	Missense	proximal	-2	no	0.000	0.013	EPSD	GDSC;CCLE	0.010	Gain
Other_Aur_AurB_ST	Q8TEW0	PARD3	Q96GD4	AURKB	S1265	Q1263K	1263	Missense	proximal	-2	no	-0.005	0.010	EPSD	GDSC;CCLE	0.010	Gain
Other_Aur_AurB_ST	O95235	KIF20A	Q96GD4	AURKB	S478	G476D	476	Missense	proximal	-2	no	0.011	0.010	EPSD	GDSC;CCLE	0.010	Down-regulation
Other_Aur_AurB_ST	O95235	KIF20A	Q96GD4	AURKB	S478	S478P	478	Missense	central	0	yes	0.011	0.000	EPSD	GDSC;CCLE	0.010	Loss
Other_Aur_AurB_ST	O95235	KIF20A	Q96GD4	AURKB	S632	S635T	635	Missense	distal	3	no	0.009	0.010	EPSD	GDSC	0.010	Gain
Other_Aur_AurB_ST	P06748	NPM1	Q96GD4	AURKB	T279	E282V	282	Missense	distal	3	no	0.068	0.069	EPSD	GDSC	0.010	Up-regulation
Other_Aur_AurB_ST	Q9H788	SH2D4A	Q96GD4	AURKB	S51	E50K	50	Missense	proximal	-1	no	0.018	0.019	EPSD	GDSC;CCLE	0.010	Up-regulation
Other_Aur_AurB_ST	Q8NG31	KNL1	Q96GD4	AURKB	S1008	R1006K	1006	Missense	proximal	-2	no	0.070	0.011	EPSD	GDSC	0.010	Down-regulation
Other_Aur_AurB_ST	Q8NG31	KNL1	Q96GD4	AURKB	T1166	C1164R	1164	Missense	proximal	-2	no	-0.001	0.069	EPSD	GDSC	0.010	Gain
Other_Aur_AurB_ST	Q8NG31	KNL1	Q96GD4	AURKB	S1448	R1446*	1446	Missense	proximal	-2	no	0.071	-0.001	EPSD	GDSC	0.010	Loss
Other_Aur_AurB_ST	Q8NG31	KNL1	Q96GD4	AURKB	S1869	Q1870*	1870	Missense	proximal	1	no	0.068	0.069	EPSD	GDSC	0.010	Up-regulation
Other_Aur_AurB_ST	Q69YH5	CDCA2	Q96GD4	AURKB	T162	K160E	160	Missense	proximal	-2	no	0.010	-0.003	EPSD	GDSC;CCLE	0.010	Loss
Other_Aur_AurB_ST	Q69YH5	CDCA2	Q96GD4	AURKB	S886	R891*	891	Missense	distal	5	no	0.076	0.078	EPSD	GDSC	0.010	Up-regulation
Other_Aur_AurB_ST	Q69YH5	CDCA2	Q96GD4	AURKB	S893	R891*	891	Missense	proximal	-2	no	0.076	0.004	PhosphoSitePlus	GDSC	0.010	Loss
Other_Aur_AurB_ST	Q9Y2R4	DDX52	Q96GD4	AURKB	T92	T92M	92	Missense	central	0	yes	0.072	0.000	EPSD	GDSC;CCLE	0.010	Loss
Other_Aur_AurB_ST	Q9Y2R4	DDX52	Q96GD4	AURKB	S565	P560R	560	Missense	distal	-5	no	0.072	0.074	EPSD	GDSC;CCLE	0.010	Up-regulation
Other_Aur_AurB_ST	P82970	HMGN5	Q96GD4	AURKB	S20	S20C	20	Missense	central	0	yes	0.081	0.000	EPSD;PhosphoSitePlus	GDSC;CCLE	0.010	Loss
Other_Aur_AurB_ST	Q8IVT2	MISP	Q96GD4	AURKB	S448	G442R	442	Missense	distal	-6	no	0.008	0.010	EPSD	GDSC;CCLE	0.010	Gain
Other_Aur_AurB_ST	Q8IVT2	MISP	Q96GD4	AURKB	T464	R468K	468	Missense	distal	4	no	0.012	0.011	EPSD	GDSC	0.010	Down-regulation
Other_Aur_AurB_ST	Q8IX03	WWC1	Q96GD4	AURKB	S523	Q519H	519	Missense	distal	-4	no	0.009	0.010	EPSD	GDSC;CCLE	0.010	Gain
Other_Aur_AurB_ST	Q8IX03	WWC1	Q96GD4	AURKB	S922	R920Q	920	Missense	proximal	-2	no	0.073	-0.001	EPSD	GDSC;CCLE	0.010	Loss
Other_Aur_AurB_ST	Q8IX03	WWC1	Q96GD4	AURKB	S974	R972W	972	Missense	proximal	-2	no	0.069	0.000	EPSD	GDSC;CCLE	0.010	Loss
Other_Aur_AurB_ST	Q9Y5B9	SUPT16H	Q96GD4	AURKB	S128	K133N	133	Missense	distal	5	no	0.010	0.011	EPSD	GDSC	0.010	Up-regulation
Other_Aur_AurB_ST	Q9Y5B9	SUPT16H	Q96GD4	AURKB	S560	S558R	558	Missense	proximal	-2	no	-0.004	0.069	EPSD	GDSC;CCLE	0.010	Gain
Other_Aur_AurB_ST	Q9Y5B9	SUPT16H	Q96GD4	AURKB	S1031	R1036T	1036	Missense	distal	5	no	0.071	0.073	EPSD	GDSC;CCLE	0.010	Up-regulation
Other_Aur_AurB_ST	Q9Y5B9	SUPT16H	Q96GD4	AURKB	S1038	R1036T	1036	Missense	proximal	-2	no	0.069	0.002	EPSD	GDSC;CCLE	0.010	Loss
Other_Aur_AurB_ST	Q9Y5B9	SUPT16H	Q96GD4	AURKB	S1038	S1038C	1038	Missense	central	0	yes	0.069	0.000	EPSD	GDSC;CCLE	0.010	Loss
Other_Aur_AurB_ST	Q92538	GBF1	Q96GD4	AURKB	S1298	G1295R	1295	Missense	distal	-3	no	0.004	0.011	EPSD	GDSC	0.010	Gain
Other_Aur_AurB_ST	Q92538	GBF1	Q96GD4	AURKB	S1453	K1451R	1451	Missense	proximal	-2	no	0.017	0.076	EPSD	GDSC;CCLE	0.010	Up-regulation
Other_Aur_AurB_ST	Q92538	GBF1	Q96GD4	AURKB	S1466	R1471W	1471	Missense	distal	5	no	0.011	0.013	EPSD	GDSC;CCLE	0.010	Up-regulation
Other_Aur_AurB_ST	Q9Y520	PRRC2C	Q96GD4	AURKB	T159	E158K	158	Missense	proximal	-1	no	0.008	0.010	EPSD	GDSC	0.010	Gain
Other_Aur_AurB_ST	Q9Y266	NUDC	Q96GD4	AURKB	T40	R38H	38	Missense	proximal	-2	no	0.078	0.007	PhosphoSitePlus	GDSC;CCLE	0.010	Loss
Other_Aur_AurB_ST	Q9BXS6	NUSAP1	Q96GD4	AURKB	S154	K161R	161	Missense	distal	7	no	0.070	0.071	EPSD	GDSC;CCLE	0.010	Up-regulation
Other_Aur_AurB_ST	Q9BXS6	NUSAP1	Q96GD4	AURKB	S363	V357A	357	Missense	distal	-6	no	0.013	0.014	EPSD	GDSC	0.010	Up-regulation
Other_Aur_AurB_ST	Q9NYP9	MIS18A	Q96GD4	AURKB	S10	R5Q	5	Missense	distal	-5	no	0.072	0.070	EPSD	GDSC;CCLE	0.010	Down-regulation
Other_Aur_AurB_ST	Q9NYP9	MIS18A	Q96GD4	AURKB	S227	T230S	230	Missense	distal	3	no	0.011	0.010	EPSD	GDSC;CCLE	0.010	Down-regulation
Other_Aur_AurB_ST	P46013	MKI67	Q96GD4	AURKB	T109	R116H	116	Missense	distal	7	no	0.020	0.019	EPSD	GDSC;CCLE	0.010	Down-regulation
Other_Aur_AurB_ST	P46013	MKI67	Q96GD4	AURKB	S396	R400*	400	Missense	distal	4	no	0.018	0.017	EPSD	GDSC	0.010	Down-regulation
Other_Aur_AurB_ST	P46013	MKI67	Q96GD4	AURKB	T401	R400*	400	Missense	proximal	-1	no	0.012	0.004	EPSD	GDSC	0.010	Loss
Other_Aur_AurB_ST	P46013	MKI67	Q96GD4	AURKB	S538	K537R	537	Missense	proximal	-1	no	0.073	0.079	EPSD;PhosphoSitePlus	GDSC;CCLE	0.010	Up-regulation
Other_Aur_AurB_ST	P46013	MKI67	Q96GD4	AURKB	S825	R831T	831	Missense	distal	6	no	0.013	0.012	EPSD	GDSC;CCLE	0.010	Down-regulation
Other_Aur_AurB_ST	P46013	MKI67	Q96GD4	AURKB	S825	R832Q	832	Missense	distal	7	no	0.013	0.012	EPSD	GDSC;CCLE	0.010	Down-regulation
Other_Aur_AurB_ST	P46013	MKI67	Q96GD4	AURKB	T852	K850E	850	Missense	proximal	-2	no	0.010	-0.003	EPSD	GDSC;CCLE	0.010	Loss
Other_Aur_AurB_ST	P46013	MKI67	Q96GD4	AURKB	T1083	K1087R	1087	Missense	distal	4	no	0.067	0.068	EPSD	GDSC;CCLE	0.010	Up-regulation
Other_Aur_AurB_ST	P46013	MKI67	Q96GD4	AURKB	T1484	T1484A	1484	Missense	central	0	yes	0.011	0.000	EPSD	GDSC	0.010	Loss
Other_Aur_AurB_ST	P46013	MKI67	Q96GD4	AURKB	S1617	K1616R	1616	Missense	proximal	-1	no	0.006	0.012	EPSD	GDSC	0.010	Gain
Other_Aur_AurB_ST	P46013	MKI67	Q96GD4	AURKB	S1618	K1616R	1616	Missense	proximal	-2	no	0.012	0.071	EPSD	GDSC	0.010	Up-regulation
Other_Aur_AurB_ST	P46013	MKI67	Q96GD4	AURKB	S1636	R1632W	1632	Missense	distal	-4	no	0.015	0.014	EPSD	GDSC	0.010	Down-regulation
Other_Aur_AurB_ST	P46013	MKI67	Q96GD4	AURKB	S1636	S1636F	1636	Missense	central	0	yes	0.015	0.000	EPSD	GDSC;CCLE	0.010	Loss
Other_Aur_AurB_ST	P46013	MKI67	Q96GD4	AURKB	T1854	K1855*	1855	Missense	proximal	1	no	0.009	0.010	EPSD	GDSC	0.010	Gain
Other_Aur_AurB_ST	P46013	MKI67	Q96GD4	AURKB	S2223	S2223Y	2223	Missense	central	0	yes	0.011	0.000	EPSD	GDSC;CCLE	0.010	Loss
Other_Aur_AurB_ST	P46013	MKI67	Q96GD4	AURKB	T2380	R2379*	2379	Missense	proximal	-1	no	0.025	0.017	EPSD	GDSC	0.010	Down-regulation
Other_Aur_AurB_ST	P46013	MKI67	Q96GD4	AURKB	S2382	R2379*	2379	Missense	distal	-3	no	0.011	0.004	EPSD	GDSC	0.010	Loss
Other_Aur_AurB_ST	P46013	MKI67	Q96GD4	AURKB	T3205	R3203S	3203	Missense	proximal	-2	no	0.073	0.000	EPSD	GDSC	0.010	Loss
Other_Aur_AurB_ST	P14618	PKM	Q96GD4	AURKB	T143	K141I	141	Missense	proximal	-2	no	0.011	-0.002	EPSD	GDSC	0.010	Loss
Other_Aur_AurB_ST	P14618	PKM	Q96GD4	AURKB	S249	S249F	249	Missense	central	0	yes	0.022	0.000	EPSD	GDSC;CCLE	0.010	Loss
Other_Aur_AurB_ST	Q9H211	CDT1	Q96GD4	AURKB	S143	R138W	138	Missense	distal	-5	no	0.017	0.015	PhosphoSitePlus	GDSC	0.010	Down-regulation
Other_Aur_AurB_ST	Q15149	PLEC	Q96GD4	AURKB	T351	R349W	349	Missense	proximal	-2	no	0.067	-0.002	EPSD	GDSC	0.010	Loss
Other_Aur_AurB_ST	Q15149	PLEC	Q96GD4	AURKB	S1124	R1121H	1121	Missense	distal	-3	no	0.013	0.006	EPSD	GDSC	0.010	Loss
Other_Aur_AurB_ST	Q15149	PLEC	Q96GD4	AURKB	S1352	R1350H	1350	Missense	proximal	-2	no	0.074	0.004	EPSD	GDSC;CCLE	0.010	Loss
Other_Aur_AurB_ST	Q15149	PLEC	Q96GD4	AURKB	S2791	R2787W	2787	Missense	distal	-4	no	0.020	0.019	EPSD	GDSC;CCLE	0.010	Down-regulation
Other_Aur_AurB_ST	Q15149	PLEC	Q96GD4	AURKB	T2886	E2889K	2889	Missense	distal	3	no	0.078	0.077	PhosphoSitePlus	GDSC;CCLE	0.010	Down-regulation
Other_Aur_AurB_ST	Q15149	PLEC	Q96GD4	AURKB	T2886	R2884W	2884	Missense	proximal	-2	no	0.078	0.008	PhosphoSitePlus	GDSC;CCLE	0.010	Loss
Other_Aur_AurB_ST	Q15149	PLEC	Q96GD4	AURKB	S3116	E3112V	3112	Missense	distal	-4	no	0.010	0.009	EPSD	GDSC;CCLE	0.010	Loss
Other_Aur_AurB_ST	Q15149	PLEC	Q96GD4	AURKB	T4267	E4264K	4264	Missense	distal	-3	no	0.071	0.072	EPSD	GDSC;CCLE	0.010	Up-regulation
Other_Aur_AurB_ST	Q15149	PLEC	Q96GD4	AURKB	S4268	E4264K	4264	Missense	distal	-4	no	0.017	0.018	EPSD	GDSC;CCLE	0.010	Up-regulation
Other_Aur_AurB_ST	Q96E39	RBMXL1	Q96GD4	AURKB	S88	R93G	93	Missense	distal	5	no	0.013	0.015	EPSD	GDSC;CCLE	0.010	Up-regulation
Other_Aur_AurB_ST	Q96E39	RBMXL1	Q96GD4	AURKB	S174	S174N	174	Missense	central	0	yes	0.073	0.000	EPSD	GDSC;CCLE	0.010	Loss
Other_Aur_AurB_ST	Q96E39	RBMXL1	Q96GD4	AURKB	S332	S329R	329	Missense	distal	-3	no	0.006	0.012	EPSD	GDSC;CCLE	0.010	Gain
Other_Aur_AurB_ST	Q96E39	RBMXL1	Q96GD4	AURKB	S362	G369R	369	Missense	distal	7	no	0.070	0.071	EPSD	GDSC;CCLE	0.010	Up-regulation
Other_Aur_AurB_ST	Q09666	AHNAK	Q96GD4	AURKB	T6	E4K	4	Missense	proximal	-2	no	-0.002	0.011	EPSD	GDSC;CCLE	0.010	Gain
Other_Aur_AurB_ST	Q09666	AHNAK	Q96GD4	AURKB	T24	G22R	22	Missense	proximal	-2	no	-0.002	0.070	EPSD	GDSC;CCLE	0.010	Gain
Other_Aur_AurB_ST	Q09666	AHNAK	Q96GD4	AURKB	T146	G144R	144	Missense	proximal	-2	no	-0.006	0.066	EPSD	GDSC;CCLE	0.010	Gain
Other_Aur_AurB_ST	Q09666	AHNAK	Q96GD4	AURKB	T486	T486A	486	Missense	central	0	yes	0.012	0.000	EPSD	GDSC;CCLE	0.010	Loss
Other_Aur_AurB_ST	Q09666	AHNAK	Q96GD4	AURKB	S1007	K1005E	1005	Missense	proximal	-2	no	0.010	-0.003	EPSD	GDSC;CCLE	0.010	Loss
Other_Aur_AurB_ST	Q09666	AHNAK	Q96GD4	AURKB	S1519	K1517T	1517	Missense	proximal	-2	no	0.011	0.002	EPSD	GDSC	0.010	Loss
Other_Aur_AurB_ST	Q09666	AHNAK	Q96GD4	AURKB	S1654	K1649R	1649	Missense	distal	-5	no	0.011	0.012	EPSD	GDSC;CCLE	0.010	Up-regulation
Other_Aur_AurB_ST	Q09666	AHNAK	Q96GD4	AURKB	S1856	M1857I	1857	Missense	proximal	1	no	0.011	0.010	EPSD	GDSC;CCLE	0.010	Down-regulation
Other_Aur_AurB_ST	Q09666	AHNAK	Q96GD4	AURKB	S2057	S2057G	2057	Missense	central	0	yes	0.011	0.000	EPSD	GDSC	0.010	Loss
Other_Aur_AurB_ST	Q09666	AHNAK	Q96GD4	AURKB	S2118	K2113R	2113	Missense	distal	-5	no	0.011	0.012	EPSD	GDSC;CCLE	0.010	Up-regulation
Other_Aur_AurB_ST	Q09666	AHNAK	Q96GD4	AURKB	S2252	E2259*	2259	Missense	distal	7	no	0.011	0.010	EPSD	GDSC	0.010	Down-regulation
Other_Aur_AurB_ST	Q09666	AHNAK	Q96GD4	AURKB	S2903	K2896R	2896	Missense	distal	-7	no	0.011	0.010	EPSD	GDSC;CCLE	0.010	Down-regulation
Other_Aur_AurB_ST	Q09666	AHNAK	Q96GD4	AURKB	S3941	K3946E	3946	Missense	distal	5	no	0.010	0.011	EPSD	GDSC	0.010	Up-regulation
Other_Aur_AurB_ST	Q09666	AHNAK	Q96GD4	AURKB	S4325	P4322L	4322	Missense	distal	-3	no	0.010	0.011	EPSD	GDSC;CCLE	0.010	Up-regulation
Other_Aur_AurB_ST	Q09666	AHNAK	Q96GD4	AURKB	S4460	K4458Q	4458	Missense	proximal	-2	no	0.010	-0.004	EPSD	GDSC;CCLE	0.010	Loss
Other_Aur_AurB_ST	Q09666	AHNAK	Q96GD4	AURKB	S4520	Q4518K	4518	Missense	proximal	-2	no	-0.004	0.011	EPSD	GDSC;CCLE	0.010	Gain
Other_Aur_AurB_ST	Q09666	AHNAK	Q96GD4	AURKB	S4900	K4898N	4898	Missense	proximal	-2	no	0.012	0.000	EPSD	GDSC;CCLE	0.010	Loss
Other_Aur_AurB_ST	Q09666	AHNAK	Q96GD4	AURKB	S5593	G5594R	5594	Missense	proximal	1	no	0.012	0.011	EPSD	GDSC;CCLE	0.010	Down-regulation
Other_Aur_AurB_ST	Q09666	AHNAK	Q96GD4	AURKB	S5762	E5760K	5760	Missense	proximal	-2	no	0.003	0.016	EPSD	GDSC;CCLE	0.010	Gain
Other_Aur_AurB_ST	Q09666	AHNAK	Q96GD4	AURKB	S5780	R5779H	5779	Missense	proximal	-1	no	0.016	0.009	EPSD	GDSC	0.010	Loss
Other_Aur_AurB_ST	O76021	RSL1D1	Q96GD4	AURKB	S392	S396R	396	Missense	distal	4	no	0.018	0.019	EPSD	GDSC;CCLE	0.010	Up-regulation
Other_Aur_AurB_ST	O76021	RSL1D1	Q96GD4	AURKB	S392	S392F	392	Missense	central	0	yes	0.018	0.000	EPSD	GDSC;CCLE	0.010	Loss
AGC_RSK_RSKp90_RPS6KA2_ST	Q15349	RPS6KA2	Q15349	RPS6KA2	S218	Y225C	225	Missense	distal	7	no	14.082	14.349	EPSD;PhosphoSitePlus	GDSC;CCLE	8.741	Up-regulation
AGC_RSK_RSKp90_RPS6KA2_ST	Q15349	RPS6KA2	Q15349	RPS6KA2	S218	G221R	221	Missense	distal	3	no	14.082	13.868	EPSD;PhosphoSitePlus	GDSC;CCLE	8.741	Down-regulation
AGC_RSK_RSKp90_RPS6KA2_ST	Q15349	RPS6KA2	Q15349	RPS6KA2	S377	H371Y	371	Missense	distal	-6	no	11.248	11.127	EPSD	GDSC	8.741	Down-regulation
AGC_RSK_RSKp90_RPS6KA2_ST	Q15349	RPS6KA2	Q15349	RPS6KA2	S544	D542Y	542	Missense	proximal	-2	no	14.088	14.031	EPSD	GDSC;CCLE	8.741	Down-regulation
AGC_RSK_RSKp90_RPS6KA2_ST	Q15349	RPS6KA2	Q15349	RPS6KA2	S544	R551*	551	Missense	distal	7	no	14.088	14.438	EPSD	GDSC	8.741	Up-regulation
AGC_RSK_RSKp90_RPS6KA2_ST	Q15349	RPS6KA2	Q15349	RPS6KA2	S628	A632S	632	Missense	distal	4	no	13.109	13.102	EPSD	GDSC;CCLE	8.741	Down-regulation
TK_Src_SrcB_BLK_Y	P12318	FCGR2A	P51451	BLK	Y281	L274F	274	Missense	distal	-7	no	2.051	2.050	EPSD	GDSC	0.806	Down-regulation
TK_Src_SrcB_BLK_Y	P12318	FCGR2A	P51451	BLK	Y304	D300N	300	Missense	distal	-4	no	1.972	1.902	PhosphoSitePlus;EPSD	GDSC;CCLE	0.806	Down-regulation
TK_Src_SrcB_BLK_Y	P31994	FCGR2B	P51451	BLK	Y292	A286V	286	Missense	distal	-6	no	2.045	2.038	PhosphoSitePlus	GDSC	0.806	Down-regulation
TK_Src_SrcB_BLK_Y	P31994	FCGR2B	P51451	BLK	Y292	L295P	295	Missense	distal	3	no	2.045	2.073	PhosphoSitePlus	GDSC;CCLE	0.806	Up-regulation
Other_NEK_NEK2_NEK2_ST	Q8N137	CNTROB	P51955	NEK2	T35	L38F	38	Missense	distal	3	no	2.877	2.805	PhosphoSitePlus;EPSD	GDSC;CCLE	1.575	Down-regulation
Other_NEK_NEK2_NEK2_ST	Q8N137	CNTROB	P51955	NEK2	S36	L38F	38	Missense	proximal	2	no	3.059	3.035	EPSD;PhosphoSitePlus	GDSC;CCLE	1.575	Down-regulation
Other_NEK_NEK2_NEK2_ST	Q8N137	CNTROB	P51955	NEK2	S41	L38F	38	Missense	distal	-3	no	2.982	3.415	EPSD;PhosphoSitePlus	GDSC;CCLE	1.575	Up-regulation
Other_NEK_NEK2_NEK2_ST	Q8N137	CNTROB	P51955	NEK2	S45	L38F	38	Missense	distal	-7	no	3.154	3.201	EPSD;PhosphoSitePlus	GDSC;CCLE	1.575	Up-regulation
Other_NEK_NEK2_NEK2_ST	Q8N137	CNTROB	P51955	NEK2	T570	T570A	570	Missense	central	0	yes	1.684	0.000	EPSD	GDSC;CCLE	1.575	Loss
Other_NEK_NEK2_NEK2_ST	Q8N137	CNTROB	P51955	NEK2	T571	T570A	570	Missense	proximal	-1	no	1.685	1.638	EPSD	GDSC;CCLE	1.575	Down-regulation
Other_NEK_NEK2_NEK2_ST	Q8N137	CNTROB	P51955	NEK2	S769	P774L	774	Missense	distal	5	no	1.748	1.506	EPSD	GDSC;CCLE	1.575	Loss
Other_NEK_NEK2_NEK2_ST	Q8N137	CNTROB	P51955	NEK2	S769	R772L	772	Missense	distal	3	no	1.748	1.952	EPSD	GDSC;CCLE	1.575	Up-regulation
Other_NEK_NEK2_NEK2_ST	Q8N137	CNTROB	P51955	NEK2	S769	M766T	766	Missense	distal	-3	no	1.748	1.306	EPSD	GDSC;CCLE	1.575	Loss
Other_NEK_NEK2_NEK2_ST	Q8N137	CNTROB	P51955	NEK2	S781	P774L	774	Missense	distal	-7	no	1.599	1.885	EPSD	GDSC;CCLE	1.575	Up-regulation
Other_NEK_NEK2_NEK2_ST	Q8N137	CNTROB	P51955	NEK2	S781	P786S	786	Missense	distal	5	no	1.599	1.487	EPSD	GDSC;CCLE	1.575	Loss
Other_NEK_NEK2_NEK2_ST	P51955	NEK2	P51955	NEK2	T170	L166*	166	Missense	distal	-4	no	2.885	2.713	EPSD;PhosphoSitePlus	GDSC	1.575	Down-regulation
Other_NEK_NEK2_NEK2_ST	P51955	NEK2	P51955	NEK2	S171	L166*	166	Missense	distal	-5	no	3.034	3.139	EPSD;PhosphoSitePlus	GDSC	1.575	Up-regulation
Other_NEK_NEK2_NEK2_ST	P51955	NEK2	P51955	NEK2	S241	R239L	239	Missense	proximal	-2	no	3.396	3.169	PhosphoSitePlus;EPSD	GDSC;CCLE	1.575	Down-regulation
Other_NEK_NEK2_NEK2_ST	P51955	NEK2	P51955	NEK2	S241	S241C	241	Missense	central	0	yes	3.396	0.000	PhosphoSitePlus;EPSD	GDSC;CCLE	1.575	Loss
Other_NEK_NEK2_NEK2_ST	P51955	NEK2	P51955	NEK2	S356	S356N	356	Missense	central	0	yes	2.945	0.000	EPSD;PhosphoSitePlus	GDSC;CCLE	1.575	Loss
Other_NEK_NEK2_NEK2_ST	P51955	NEK2	P51955	NEK2	S378	V379A	379	Missense	proximal	1	no	1.652	1.600	EPSD	GDSC;CCLE	1.575	Down-regulation
Other_NEK_NEK2_NEK2_ST	P51955	NEK2	P51955	NEK2	S397	N393K	393	Missense	distal	-4	no	3.078	3.003	EPSD;PhosphoSitePlus	GDSC;CCLE	1.575	Down-regulation
Other_NEK_NEK2_NEK2_ST	Q9H2D6	TRIOBP	P51955	NEK2	T714	R713K	713	Missense	proximal	-1	no	1.575	1.178	EPSD	GDSC	1.575	Loss
Other_NEK_NEK2_NEK2_ST	Q9H2D6	TRIOBP	P51955	NEK2	T714	Q717R	717	Missense	distal	3	no	1.575	1.559	EPSD	GDSC	1.575	Loss
Other_NEK_NEK2_NEK2_ST	Q9H2D6	TRIOBP	P51955	NEK2	T715	R713K	713	Missense	proximal	-2	no	1.934	1.766	EPSD	GDSC	1.575	Down-regulation
Other_NEK_NEK2_NEK2_ST	Q9H2D6	TRIOBP	P51955	NEK2	T715	Q717R	717	Missense	proximal	2	no	1.934	1.927	EPSD	GDSC	1.575	Down-regulation
Other_NEK_NEK2_NEK2_ST	Q9H2D6	TRIOBP	P51955	NEK2	S757	A756T	756	Missense	proximal	-1	no	1.652	1.698	EPSD	GDSC	1.575	Up-regulation
Other_NEK_NEK2_NEK2_ST	Q9H2D6	TRIOBP	P51955	NEK2	S757	N760S	760	Missense	distal	3	no	1.652	1.718	EPSD	GDSC	1.575	Up-regulation
Other_NEK_NEK2_NEK2_ST	Q9H2D6	TRIOBP	P51955	NEK2	S895	R899G	899	Missense	distal	4	no	1.687	1.545	EPSD	GDSC;CCLE	1.575	Loss
Other_NEK_NEK2_NEK2_ST	Q9H2D6	TRIOBP	P51955	NEK2	S1235	S1235G	1235	Missense	central	0	yes	2.033	0.000	EPSD	GDSC;CCLE	1.575	Loss
Other_NEK_NEK2_NEK2_ST	Q9H2D6	TRIOBP	P51955	NEK2	S1235	R1231H	1231	Missense	distal	-4	no	2.033	2.020	EPSD	GDSC;CCLE	1.575	Down-regulation
Other_NEK_NEK2_NEK2_ST	Q9H2D6	TRIOBP	P51955	NEK2	S1235	A1238S	1238	Missense	distal	3	no	2.033	2.073	EPSD	GDSC;CCLE	1.575	Up-regulation
Other_NEK_NEK2_NEK2_ST	Q9H2D6	TRIOBP	P51955	NEK2	S1243	A1238S	1238	Missense	distal	-5	no	1.670	1.659	EPSD	GDSC;CCLE	1.575	Down-regulation
Other_NEK_NEK2_NEK2_ST	Q92997	DVL3	P51955	NEK2	T135	D132G	132	Missense	distal	-3	no	1.636	2.426	EPSD	GDSC	1.575	Up-regulation
Other_NEK_NEK2_NEK2_ST	Q92997	DVL3	P51955	NEK2	S280	A286D	286	Missense	distal	6	no	2.946	3.269	EPSD;PhosphoSitePlus	GDSC;CCLE	1.575	Up-regulation
Other_NEK_NEK2_NEK2_ST	Q92997	DVL3	P51955	NEK2	S280	Y277C	277	Missense	distal	-3	no	2.946	2.005	EPSD;PhosphoSitePlus	GDSC;CCLE	1.575	Down-regulation
Other_NEK_NEK2_NEK2_ST	Q92997	DVL3	P51955	NEK2	S697	A696T	696	Missense	proximal	-1	no	1.985	2.032	EPSD;PhosphoSitePlus	GDSC;CCLE	1.575	Up-regulation
Other_NEK_NEK2_NEK2_ST	Q92997	DVL3	P51955	NEK2	S697	R698T	698	Missense	proximal	1	no	1.985	1.954	EPSD;PhosphoSitePlus	GDSC;CCLE	1.575	Down-regulation
Other_NEK_NEK2_NEK2_ST	P54274	TERF1	P51955	NEK2	S160	E162G	162	Missense	proximal	2	no	2.941	3.018	EPSD	GDSC;CCLE	1.575	Up-regulation
Other_NEK_NEK2_NEK2_ST	P06748	NPM1	P51955	NEK2	S143	A144T	144	Missense	proximal	1	no	1.686	1.726	EPSD	GDSC;CCLE	1.575	Up-regulation
Other_NEK_NEK2_NEK2_ST	P06748	NPM1	P51955	NEK2	S227	P220L	220	Missense	distal	-7	no	1.441	1.727	EPSD	GDSC;CCLE	1.575	Gain
Other_NEK_NEK2_NEK2_ST	Q5FBB7	SGO1	P51955	NEK2	S14	D13G	13	Missense	proximal	-1	no	2.279	2.608	PhosphoSitePlus;EPSD	GDSC	1.575	Up-regulation
Other_NEK_NEK2_NEK2_ST	O15360	FANCA	P51955	NEK2	T351	R350W	350	Missense	proximal	-1	no	3.148	3.014	PhosphoSitePlus	GDSC;CCLE	1.575	Down-regulation
Other_NEK_NEK2_NEK2_ST	O15360	FANCA	P51955	NEK2	S357	R350W	350	Missense	distal	-7	no	1.604	1.508	EPSD	GDSC;CCLE	1.575	Loss
Other_NEK_NEK2_NEK2_ST	O14777	NDC80	P51955	NEK2	S77	P83L	83	Missense	distal	6	no	1.618	1.590	EPSD	GDSC;CCLE	1.575	Down-regulation
Other_NEK_NEK2_NEK2_ST	Q96CN5	LRRC45	P51955	NEK2	T328	Q333H	333	Missense	distal	5	no	1.661	1.790	EPSD	GDSC;CCLE	1.575	Up-regulation
Other_NEK_NEK2_NEK2_ST	Q96CN5	LRRC45	P51955	NEK2	S337	Q333H	333	Missense	distal	-4	no	1.801	1.856	EPSD	GDSC;CCLE	1.575	Up-regulation
Other_NEK_NEK2_NEK2_ST	Q96CN5	LRRC45	P51955	NEK2	S399	A402D	402	Missense	distal	3	no	1.751	1.621	EPSD	GDSC;CCLE	1.575	Down-regulation
Other_NEK_NEK2_NEK2_ST	P04637	TP53	P51955	NEK2	S106	K101*	101	Missense	distal	-5	no	1.544	1.691	EPSD	GDSC	1.575	Gain
Other_NEK_NEK2_NEK2_ST	P04637	TP53	P51955	NEK2	S106	Y107*	107	Missense	proximal	1	no	1.544	1.649	EPSD	GDSC	1.575	Gain
Other_NEK_NEK2_NEK2_ST	P04637	TP53	P51955	NEK2	T125	Y126*	126	Missense	proximal	1	no	1.654	1.760	EPSD	GDSC	1.575	Up-regulation
Other_NEK_NEK2_NEK2_ST	P04637	TP53	P51955	NEK2	T125	K120*	120	Missense	distal	-5	no	1.654	1.802	EPSD	GDSC	1.575	Up-regulation
Other_NEK_NEK2_NEK2_ST	P04637	TP53	P51955	NEK2	S215	R213*	213	Missense	proximal	-2	no	1.693	1.323	EPSD	GDSC	1.575	Loss
Other_NEK_NEK2_NEK2_ST	P04637	TP53	P51955	NEK2	S215	R209*	209	Missense	distal	-6	no	1.693	1.696	EPSD	GDSC	1.575	Up-regulation
Other_NEK_NEK2_NEK2_ST	P04637	TP53	P51955	NEK2	S269	E271*	271	Missense	proximal	2	no	1.358	1.579	EPSD	GDSC	1.575	Gain
CAMK_PIM_PIM1_ST	Q13309	SKP2	P11309	PIM1	S48	K43N	43	Missense	distal	-5	no	0.001	0.000	EPSD	GDSC;CCLE	0.001	Loss
CAMK_PIM_PIM1_ST	Q99683	MAP3K5	P11309	PIM1	S83	S83C	83	Missense	central	0	yes	0.002	0.000	PhosphoSitePlus	GDSC;CCLE	0.001	Loss
CAMK_PIM_PIM1_ST	Q99683	MAP3K5	P11309	PIM1	S267	S267R	267	Missense	central	0	yes	0.001	0.000	EPSD	GDSC	0.001	Loss
CAMK_PIM_PIM1_ST	Q99683	MAP3K5	P11309	PIM1	S763	G760R	760	Missense	distal	-3	no	0.000	0.001	EPSD	GDSC	0.001	Gain
CAMK_PIM_PIM1_ST	Q99683	MAP3K5	P11309	PIM1	S955	S955L	955	Missense	central	0	yes	0.001	0.000	EPSD	GDSC;CCLE	0.001	Loss
CAMK_PIM_PIM1_ST	P38936	CDKN1A	P11309	PIM1	T145	R143Q	143	Missense	proximal	-2	no	0.003	0.002	EPSD;PhosphoSitePlus	GDSC;CCLE	0.001	Down-regulation
CAMK_PIM_PIM1_ST	P38936	CDKN1A	P11309	PIM1	S146	R143Q	143	Missense	distal	-3	no	0.002	0.001	PhosphoSitePlus;EPSD	GDSC;CCLE	0.001	Down-regulation
CAMK_PIM_PIM1_ST	P27448	MARK3	P11309	PIM1	S391	R388T	388	Missense	distal	-3	no	0.002	0.001	EPSD	GDSC;CCLE	0.001	Down-regulation
CAMK_PIM_PIM1_ST	P27448	MARK3	P11309	PIM1	T602	R597*	597	Missense	distal	-5	no	0.002	0.001	EPSD	GDSC	0.001	Down-regulation
CAMK_PIM_PIM1_ST	P27448	MARK3	P11309	PIM1	S643	S643F	643	Missense	central	0	yes	0.001	0.000	EPSD	GDSC;CCLE	0.001	Loss
CAMK_PIM_PIM1_ST	P27448	MARK3	P11309	PIM1	S668	S663I	663	Missense	distal	-5	no	0.000	0.001	EPSD	GDSC;CCLE	0.001	Gain
CAMK_PIM_PIM1_ST	Q01860	POU5F1	P11309	PIM1	S290	R287*	287	Missense	distal	-3	no	0.001	0.000	EPSD	GDSC	0.001	Loss
CAMK_PIM_PIM1_ST	P35568	IRS1	P11309	PIM1	S270	R267C	267	Missense	distal	-3	no	0.002	0.001	EPSD	GDSC;CCLE	0.001	Down-regulation
CAMK_PIM_PIM1_ST	P35568	IRS1	P11309	PIM1	S272	R267C	267	Missense	distal	-5	no	0.002	0.001	EPSD	GDSC;CCLE	0.001	Down-regulation
CAMK_PIM_PIM1_ST	P35568	IRS1	P11309	PIM1	S374	H371R	371	Missense	distal	-3	no	0.000	0.001	EPSD	GDSC	0.001	Gain
CAMK_PIM_PIM1_ST	P35568	IRS1	P11309	PIM1	T859	R854C	854	Missense	distal	-5	no	0.001	0.000	EPSD	GDSC	0.001	Loss
CAMK_PIM_PIM1_ST	P35568	IRS1	P11309	PIM1	S1084	S1084R	1084	Missense	central	0	yes	0.001	0.000	EPSD	GDSC	0.001	Loss
CAMK_PIM_PIM1_ST	P35568	IRS1	P11309	PIM1	S1101	R1096G	1096	Missense	distal	-5	no	0.003	0.001	PhosphoSitePlus	GDSC;CCLE	0.001	Down-regulation
CAMK_PIM_PIM1_ST	O43524	FOXO3	P11309	PIM1	S412	R410W	410	Missense	proximal	-2	no	0.001	0.000	EPSD	GDSC;CCLE	0.001	Loss
CAMK_PIM_PIM1_ST	O43524	FOXO3	P11309	PIM1	S413	R410W	410	Missense	distal	-3	no	0.001	0.000	EPSD	GDSC;CCLE	0.001	Loss
CAMK_PIM_PIM1_ST	P29474	NOS3	P11309	PIM1	S633	R628Q	628	Missense	distal	-5	no	0.003	0.002	PhosphoSitePlus	GDSC	0.001	Down-regulation
CAMK_PIM_PIM1_ST	P29474	NOS3	P11309	PIM1	T854	T854M	854	Missense	central	0	yes	0.001	0.000	EPSD	GDSC	0.001	Loss
CAMK_PIM_PIM1_ST	P29474	NOS3	P11309	PIM1	T1175	R1172C	1172	Missense	distal	-3	no	0.001	0.000	EPSD	GDSC;CCLE	0.001	Loss
CAMK_PIM_PIM1_ST	P29474	NOS3	P11309	PIM1	T1175	T1170K	1170	Missense	distal	-5	no	0.001	0.002	EPSD	GDSC	0.001	Up-regulation
CAMK_PIM_PIM1_ST	P29474	NOS3	P11309	PIM1	S1177	R1174C	1174	Missense	distal	-3	no	0.002	0.001	EPSD	GDSC;CCLE	0.001	Down-regulation
CAMK_PIM_PIM1_ST	P29474	NOS3	P11309	PIM1	S1177	R1172C	1172	Missense	distal	-5	no	0.002	0.001	EPSD	GDSC;CCLE	0.001	Down-regulation
CAMK_PIM_PIM1_ST	P29474	NOS3	P11309	PIM1	S1177	T1170K	1170	Missense	distal	-7	no	0.002	0.003	EPSD	GDSC	0.001	Up-regulation
CAMK_PIM_PIM1_ST	P29474	NOS3	P11309	PIM1	S1179	R1174C	1174	Missense	distal	-5	no	0.002	0.000	EPSD	GDSC;CCLE	0.001	Loss
CAMK_PIM_PIM1_ST	O60381	HBP1	P11309	PIM1	S422	K416Q	416	Missense	distal	-6	no	0.001	0.000	EPSD	GDSC;CCLE	0.001	Loss
CAMK_PIM_PIM1_ST	O60381	HBP1	P11309	PIM1	S422	N420S	420	Missense	proximal	-2	no	0.001	0.000	EPSD	GDSC;CCLE	0.001	Loss
CAMK_PIM_PIM1_ST	Q99801	NKX3-1	P11309	PIM1	S48	S48R	48	Missense	central	0	yes	0.001	0.000	EPSD	GDSC;CCLE	0.001	Loss
CAMK_PIM_PIM1_ST	Q9UNQ0	ABCG2	P11309	PIM1	S50	R45*	45	Missense	distal	-5	no	0.002	0.001	EPSD	GDSC	0.001	Down-regulation
CAMK_PIM_PIM1_ST	P10275	AR	P11309	PIM1	T851	T851A	851	Missense	central	0	yes	0.002	0.000	PhosphoSitePlus;EPSD	GDSC;CCLE	0.001	Loss
STE_STE20_MST_STK4_ST	Q14457	BECN1	Q13043	STK4	S7	Q13*	13	Missense	distal	6	no	4.905	4.897	EPSD	GDSC	4.850	Down-regulation
STE_STE20_MST_STK4_ST	Q14457	BECN1	Q13043	STK4	S7	S10N	10	Missense	distal	3	no	4.905	4.889	EPSD	GDSC;CCLE	4.850	Down-regulation
STE_STE20_MST_STK4_ST	Q14457	BECN1	Q13043	STK4	S10	Q13*	13	Missense	distal	3	no	4.885	4.884	EPSD	GDSC	4.850	Down-regulation
STE_STE20_MST_STK4_ST	Q14457	BECN1	Q13043	STK4	S10	S10N	10	Missense	central	0	yes	4.885	0.000	EPSD	GDSC;CCLE	4.850	Loss
STE_STE20_MST_STK4_ST	Q14457	BECN1	Q13043	STK4	T11	Q13*	13	Missense	proximal	2	no	4.982	4.959	EPSD	GDSC	4.850	Down-regulation
STE_STE20_MST_STK4_ST	Q14457	BECN1	Q13043	STK4	S15	Q13*	13	Missense	proximal	-2	no	4.947	4.936	EPSD	GDSC	4.850	Down-regulation
STE_STE20_MST_STK4_ST	Q14457	BECN1	Q13043	STK4	S15	S10N	10	Missense	distal	-5	no	4.947	4.991	EPSD	GDSC;CCLE	4.850	Up-regulation
STE_STE20_MST_STK4_ST	Q14457	BECN1	Q13043	STK4	T108	M109I	109	Missense	proximal	1	no	4.899	4.882	PhosphoSitePlus	GDSC;CCLE	4.850	Down-regulation
STE_STE20_MST_STK4_ST	Q14457	BECN1	Q13043	STK4	T417	S421T	421	Missense	distal	4	no	4.873	4.824	EPSD	GDSC;CCLE	4.850	Loss
STE_STE20_MST_STK4_ST	Q06830	PRDX1	Q13043	STK4	T18	P11R	11	Missense	distal	-7	no	4.889	4.891	EPSD;PhosphoSitePlus	GDSC	4.850	Up-regulation
STE_STE20_MST_STK4_ST	P19429	TNNI3	Q13043	STK4	S5	A8V	8	Missense	distal	3	no	4.878	4.859	EPSD	GDSC	4.850	Down-regulation
STE_STE20_MST_STK4_ST	Q13043	STK4	Q13043	STK4	S21	S21R	21	Missense	central	0	yes	4.871	0.000	EPSD	GDSC;CCLE	4.850	Loss
STE_STE20_MST_STK4_ST	Q13043	STK4	Q13043	STK4	S21	E28*	28	Missense	distal	7	no	4.871	4.892	EPSD	GDSC	4.850	Up-regulation
STE_STE20_MST_STK4_ST	Q13043	STK4	Q13043	STK4	T23	S21R	21	Missense	proximal	-2	no	4.974	4.990	EPSD	GDSC;CCLE	4.850	Up-regulation
STE_STE20_MST_STK4_ST	Q13043	STK4	Q13043	STK4	T23	E28*	28	Missense	distal	5	no	4.974	4.987	EPSD	GDSC	4.850	Up-regulation
STE_STE20_MST_STK4_ST	Q13043	STK4	Q13043	STK4	S327	D326N	326	Missense	proximal	-1	no	4.895	4.894	EPSD	GDSC;CCLE	4.850	Down-regulation
STE_STE20_MST_STK4_ST	Q13043	STK4	Q13043	STK4	S327	D326H	326	Missense	proximal	-1	no	4.895	4.893	EPSD	GDSC;CCLE	4.850	Down-regulation
STE_STE20_MST_STK4_ST	O43524	FOXO3	Q13043	STK4	S200	F194L	194	Missense	distal	-6	no	4.885	4.901	EPSD	GDSC;CCLE	4.850	Up-regulation
STE_STE20_MST_STK4_ST	O43524	FOXO3	Q13043	STK4	S243	R249W	249	Missense	distal	6	no	5.018	5.006	EPSD;PhosphoSitePlus	GDSC;CCLE	4.850	Down-regulation
STE_STE20_MST_STK4_ST	Q96GD4	AURKB	Q13043	STK4	S22	R27*	27	Missense	distal	5	no	4.841	4.850	EPSD	GDSC	4.850	Gain
STE_STE20_MST_STK4_ST	Q7L9L4	MOB1B	Q13043	STK4	T12	N18S	18	Missense	distal	6	no	4.944	4.940	EPSD;PhosphoSitePlus	GDSC;CCLE	4.850	Down-regulation
STE_STE20_MST_STK4_ST	Q7L9L4	MOB1B	Q13043	STK4	S23	P20L	20	Missense	distal	-3	no	4.851	4.852	EPSD	GDSC	4.850	Up-regulation
STE_STE20_MST_STK4_ST	Q7L9L4	MOB1B	Q13043	STK4	S23	G22C	22	Missense	proximal	-1	no	4.851	4.848	EPSD	GDSC;CCLE	4.850	Loss
STE_STE20_MST_STK4_ST	Q7L9L4	MOB1B	Q13043	STK4	S23	N18S	18	Missense	distal	-5	no	4.851	4.806	EPSD	GDSC;CCLE	4.850	Loss
STE_STE20_MST_STK4_ST	Q7L9L4	MOB1B	Q13043	STK4	S38	A44T	44	Missense	distal	6	no	4.923	4.925	EPSD	GDSC;CCLE	4.850	Up-regulation
STE_STE20_MST_STK4_ST	Q7L9L4	MOB1B	Q13043	STK4	S38	G37D	37	Missense	proximal	-1	no	4.923	4.920	EPSD	GDSC;CCLE	4.850	Down-regulation
Other_MOS_MOS_ST	P08670	VIM	P00540	MOS	T458	T458A	458	Missense	central	0	yes	2.469	0.000	EPSD;PhosphoSitePlus	GDSC;CCLE	2.415	Loss
Other_MOS_MOS_ST	P08670	VIM	P00540	MOS	S459	T458A	458	Missense	proximal	-1	no	2.783	2.787	PhosphoSitePlus;EPSD	GDSC;CCLE	2.415	Up-regulation
STE_STE20_KHS_MAP4K3_ST	Q04759	PRKCQ	Q8IVH8	MAP4K3	S297	M294I	294	Missense	distal	-3	no	3.094	3.092	EPSD	GDSC;CCLE	2.839	Down-regulation
STE_STE20_KHS_MAP4K3_ST	Q04759	PRKCQ	Q8IVH8	MAP4K3	T538	D533E	533	Missense	distal	-5	no	8.554	8.440	PhosphoSitePlus	GDSC;CCLE	2.839	Down-regulation
STE_STE20_KHS_MAP4K3_ST	P19484	TFEB	Q8IVH8	MAP4K3	S133	A139V	139	Missense	distal	6	no	2.928	2.949	EPSD	GDSC;CCLE	2.839	Up-regulation
STE_STE20_KHS_MAP4K3_ST	Q8IVH8	MAP4K3	Q8IVH8	MAP4K3	S170	A163G	163	Missense	distal	-7	no	10.328	10.211	PhosphoSitePlus	GDSC;CCLE	2.839	Down-regulation
PKL_FJ_FAM20C_ST	Q9GZV9	FGF23	Q8IXL6	FAM20C	S180	D184G	184	Missense	distal	4	no	6.631	6.634	PhosphoSitePlus	GDSC	2.180	Up-regulation
PKL_FJ_FAM20C_ST	Q9GZV9	FGF23	Q8IXL6	FAM20C	S180	R187G	187	Missense	distal	7	no	6.631	6.688	PhosphoSitePlus	GDSC;CCLE	2.180	Up-regulation
PKL_FJ_FAM20C_ST	P23327	HRC	Q8IXL6	FAM20C	S494	E490K	490	Missense	distal	-4	no	2.040	2.204	EPSD	GDSC;CCLE	2.180	Gain
PKL_FJ_FAM20C_ST	P23327	HRC	Q8IXL6	FAM20C	S501	G505E	505	Missense	distal	4	no	2.419	2.423	EPSD	GDSC;CCLE	2.180	Up-regulation
TK_Eph_EPHA4_Y	P54764	EPHA4	P54764	EPHA4	Y596	F600I	600	Missense	distal	4	no	4.449	4.454	EPSD;PhosphoSitePlus	GDSC;CCLE	1.226	Up-regulation
TK_Eph_EPHA4_Y	P54764	EPHA4	P54764	EPHA4	Y602	F600I	600	Missense	proximal	-2	no	4.080	4.022	PhosphoSitePlus;EPSD	GDSC;CCLE	1.226	Down-regulation
CMGC_MAPK_ERK3_MAPK6_ST	Q9Y6Q9	NCOA3	Q16659	MAPK6	S636	P641S	641	Missense	distal	5	no	3.160	2.429	EPSD	GDSC;CCLE	2.026	Down-regulation
CMGC_MAPK_ERK3_MAPK6_ST	Q9Y6Q9	NCOA3	Q16659	MAPK6	S640	P641S	641	Missense	proximal	1	no	2.062	2.045	EPSD	GDSC;CCLE	2.026	Down-regulation
CMGC_MAPK_ERK3_MAPK6_ST	Q9Y6Q9	NCOA3	Q16659	MAPK6	S652	S657F	657	Missense	distal	5	no	2.249	1.929	EPSD	GDSC;CCLE	2.026	Loss
CMGC_MAPK_ERK3_MAPK6_ST	Q9Y6Q9	NCOA3	Q16659	MAPK6	S655	S657F	657	Missense	proximal	2	no	2.252	2.321	EPSD	GDSC;CCLE	2.026	Up-regulation
CMGC_MAPK_ERK3_MAPK6_ST	Q9Y6Q9	NCOA3	Q16659	MAPK6	T663	S657F	657	Missense	distal	-6	no	2.516	2.508	EPSD	GDSC;CCLE	2.026	Down-regulation
CMGC_MAPK_ERK3_MAPK6_ST	Q9Y6Q9	NCOA3	Q16659	MAPK6	S664	S657F	657	Missense	distal	-7	no	2.208	2.227	EPSD	GDSC;CCLE	2.026	Up-regulation
CMGC_MAPK_ERK3_MAPK6_ST	Q9Y6Q9	NCOA3	Q16659	MAPK6	S857	Y852C	852	Missense	distal	-5	no	6.156	6.051	PhosphoSitePlus	GDSC;CCLE	2.026	Down-regulation
CMGC_MAPK_ERK3_MAPK6_ST	Q9Y6Q9	NCOA3	Q16659	MAPK6	T947	D944E	944	Missense	distal	-3	no	2.435	2.432	EPSD	GDSC;CCLE	2.026	Down-regulation
CMGC_MAPK_ERK3_MAPK6_ST	O95551	TDP2	Q16659	MAPK6	T92	D94H	94	Missense	proximal	2	no	2.827	2.761	EPSD	GDSC;CCLE	2.026	Down-regulation
CAMK_CAMK2_CAMK2G_ST	P98082	DAB2	Q13555	CAMK2G	S227	N226S	226	Missense	proximal	-1	no	2.833	2.983	EPSD	GDSC	2.962	Gain
CAMK_CAMK2_CAMK2G_ST	P98082	DAB2	Q13555	CAMK2G	T371	W364R	364	Missense	distal	-7	no	2.898	3.550	EPSD	GDSC	2.962	Gain
CAMK_CAMK2_CAMK2G_ST	P98082	DAB2	Q13555	CAMK2G	S723	P719H	719	Missense	distal	-4	no	6.673	6.701	PhosphoSitePlus	GDSC	2.962	Up-regulation
CAMK_CAMK2_CAMK2G_ST	Q16625	OCLN	Q13555	CAMK2G	S159	A152V	152	Missense	distal	-7	no	3.044	2.959	EPSD	GDSC	2.962	Loss
CAMK_CAMK2_CAMK2G_ST	O95180	CACNA1H	Q13555	CAMK2G	S1920	K1918N	1918	Missense	proximal	-2	no	3.175	3.063	EPSD	GDSC;CCLE	2.962	Down-regulation
CAMK_CAMK2_CAMK2G_ST	O95180	CACNA1H	Q13555	CAMK2G	S2137	A2140T	2140	Missense	distal	3	no	3.954	4.021	EPSD	GDSC	2.962	Up-regulation
CAMK_CAMK2_CAMK2G_ST	O95180	CACNA1H	Q13555	CAMK2G	S2137	F2143L	2143	Missense	distal	6	no	3.954	3.518	EPSD	GDSC;CCLE	2.962	Down-regulation
Atypical_PDHK_PDHK_PDK1_ST	P29803	PDHA2	Q15118	PDK1	S230	E232K	232	Missense	proximal	2	no	0.332	0.324	EPSD;PhosphoSitePlus	GDSC;CCLE	0.124	Down-regulation
Atypical_PDHK_PDHK_PDK1_ST	P29803	PDHA2	Q15118	PDK1	S291	V297F	297	Missense	distal	6	no	0.357	0.354	EPSD;PhosphoSitePlus	GDSC;CCLE	0.124	Down-regulation
Atypical_PDHK_PDHK_PDK1_ST	P29803	PDHA2	Q15118	PDK1	S293	V297F	297	Missense	distal	4	no	0.147	0.140	EPSD	GDSC;CCLE	0.124	Down-regulation
Atypical_PDHK_PDHK_PDK1_ST	P29803	PDHA2	Q15118	PDK1	S298	V297F	297	Missense	proximal	-1	no	0.318	0.320	PhosphoSitePlus;EPSD	GDSC;CCLE	0.124	Up-regulation
CMGC_MAPK_JNK_MAPK8_ST	Q96EB6	SIRT1	P45983	MAPK8	T177	T177I	177	Missense	central	0	yes	7.863	0.000	EPSD	GDSC;CCLE	2.638	Loss
CMGC_MAPK_JNK_MAPK8_ST	P46937	YAP1	P45983	MAPK8	T154	R161*	161	Missense	distal	7	no	7.506	7.542	PhosphoSitePlus;EPSD	GDSC	2.638	Up-regulation
CMGC_MAPK_JNK_MAPK8_ST	P46937	YAP1	P45983	MAPK8	S340	A347S	347	Missense	distal	7	no	11.219	11.213	EPSD	GDSC	2.638	Down-regulation
CMGC_MAPK_JNK_MAPK8_ST	P36956	SREBF1	P45983	MAPK8	T105	P99T	99	Missense	distal	-6	no	5.927	5.863	EPSD	GDSC	2.638	Down-regulation
CMGC_MAPK_JNK_MAPK8_ST	P36956	SREBF1	P45983	MAPK8	S386	L387P	387	Missense	proximal	1	no	-0.660	6.912	EPSD	GDSC	2.638	Gain
CMGC_MAPK_JNK_MAPK8_ST	P10636	MAPT	P45983	MAPK8	S46	Q49H	49	Missense	distal	3	no	6.230	6.337	EPSD	GDSC	2.638	Up-regulation
CMGC_MAPK_JNK_MAPK8_ST	P10636	MAPT	P45983	MAPK8	S46	A41V	41	Missense	distal	-5	no	6.230	6.771	EPSD	GDSC;CCLE	2.638	Up-regulation
CMGC_MAPK_JNK_MAPK8_ST	P10636	MAPT	P45983	MAPK8	T50	Q49H	49	Missense	proximal	-1	no	8.886	8.871	EPSD	GDSC	2.638	Down-regulation
CMGC_MAPK_JNK_MAPK8_ST	P10636	MAPT	P45983	MAPK8	S228	R222H	222	Missense	distal	-6	no	9.293	9.271	EPSD	GDSC;CCLE	2.638	Down-regulation
CMGC_MAPK_JNK_MAPK8_ST	P10636	MAPT	P45983	MAPK8	T470	A475V	475	Missense	distal	5	no	7.835	7.908	EPSD	GDSC;CCLE	2.638	Up-regulation
CMGC_MAPK_JNK_MAPK8_ST	P10636	MAPT	P45983	MAPK8	S733	S739C	739	Missense	distal	6	no	3.219	3.171	EPSD	GDSC	2.638	Down-regulation
CMGC_MAPK_JNK_MAPK8_ST	P10636	MAPT	P45983	MAPK8	S739	S739C	739	Missense	central	0	yes	7.702	0.000	EPSD	GDSC	2.638	Loss
CMGC_MAPK_JNK_MAPK8_ST	P17275	JUNB	P45983	MAPK8	T102	N96S	96	Missense	distal	-6	no	8.898	8.722	PhosphoSitePlus;EPSD	GDSC;CCLE	2.638	Down-regulation
CMGC_MAPK_JNK_MAPK8_ST	Q9NRA8	EIF4ENIF1	P45983	MAPK8	S138	R135H	135	Missense	distal	-3	no	6.232	6.269	EPSD	GDSC	2.638	Up-regulation
CMGC_MAPK_JNK_MAPK8_ST	Q9NRA8	EIF4ENIF1	P45983	MAPK8	S138	G137E	137	Missense	proximal	-1	no	6.232	6.261	EPSD	GDSC;CCLE	2.638	Up-regulation
CMGC_MAPK_JNK_MAPK8_ST	Q9NRA8	EIF4ENIF1	P45983	MAPK8	S138	K142E	142	Missense	distal	4	no	6.232	6.151	EPSD	GDSC;CCLE	2.638	Down-regulation
CMGC_MAPK_JNK_MAPK8_ST	Q9NRA8	EIF4ENIF1	P45983	MAPK8	T357	P358T	358	Missense	proximal	1	no	7.279	0.293	EPSD	GDSC;CCLE	2.638	Loss
CMGC_MAPK_JNK_MAPK8_ST	Q9NRA8	EIF4ENIF1	P45983	MAPK8	T357	G355W	355	Missense	proximal	-2	no	7.279	7.272	EPSD	GDSC;CCLE	2.638	Down-regulation
CMGC_MAPK_JNK_MAPK8_ST	Q9NRA8	EIF4ENIF1	P45983	MAPK8	S374	I372V	372	Missense	proximal	-2	no	6.958	6.820	EPSD;PhosphoSitePlus	GDSC	2.638	Down-regulation
CMGC_MAPK_JNK_MAPK8_ST	Q9NRA8	EIF4ENIF1	P45983	MAPK8	S680	S681P	681	Missense	proximal	1	no	-1.724	6.005	EPSD	GDSC	2.638	Gain
CMGC_MAPK_JNK_MAPK8_ST	Q9NRA8	EIF4ENIF1	P45983	MAPK8	S681	S681P	681	Missense	central	0	yes	8.891	0.000	EPSD	GDSC	2.638	Loss
CMGC_MAPK_JNK_MAPK8_ST	Q9NRA8	EIF4ENIF1	P45983	MAPK8	S687	S681P	681	Missense	distal	-6	no	2.887	2.976	EPSD	GDSC	2.638	Up-regulation
CMGC_MAPK_JNK_MAPK8_ST	Q9NRA8	EIF4ENIF1	P45983	MAPK8	S746	P745H	745	Missense	proximal	-1	no	3.118	3.108	EPSD	GDSC;CCLE	2.638	Down-regulation
CMGC_MAPK_JNK_MAPK8_ST	Q9NRA8	EIF4ENIF1	P45983	MAPK8	S752	P745H	745	Missense	distal	-7	no	9.877	9.883	EPSD;PhosphoSitePlus	GDSC;CCLE	2.638	Up-regulation
CMGC_MAPK_JNK_MAPK8_ST	Q9NRA8	EIF4ENIF1	P45983	MAPK8	T802	R806C	806	Missense	distal	4	no	6.224	6.258	EPSD	GDSC;CCLE	2.638	Up-regulation
CMGC_MAPK_JNK_MAPK8_ST	Q9NRA8	EIF4ENIF1	P45983	MAPK8	T923	T924P	924	Missense	proximal	1	no	0.336	7.323	EPSD	GDSC	2.638	Gain
CMGC_MAPK_JNK_MAPK8_ST	Q9NRA8	EIF4ENIF1	P45983	MAPK8	T924	T924P	924	Missense	central	0	yes	8.601	0.000	EPSD	GDSC	2.638	Loss
CMGC_MAPK_JNK_MAPK8_ST	Q05639	EEF1A2	P45983	MAPK8	T22	T22I	22	Missense	central	0	yes	3.146	0.000	EPSD	GDSC;CCLE	2.638	Loss
CMGC_MAPK_JNK_MAPK8_ST	Q9H211	CDT1	P45983	MAPK8	S79	A85S	85	Missense	distal	6	no	9.355	9.358	EPSD	GDSC;CCLE	2.638	Up-regulation
CMGC_MAPK_JNK_MAPK8_ST	Q9H211	CDT1	P45983	MAPK8	S79	T82P	82	Missense	distal	3	no	9.355	9.453	EPSD	GDSC	2.638	Up-regulation
CMGC_MAPK_JNK_MAPK8_ST	Q9H211	CDT1	P45983	MAPK8	S79	P83L	83	Missense	distal	4	no	9.355	8.948	EPSD	GDSC	2.638	Down-regulation
CMGC_MAPK_JNK_MAPK8_ST	Q9H211	CDT1	P45983	MAPK8	S81	T82P	82	Missense	proximal	1	no	-0.361	6.625	EPSD	GDSC	2.638	Gain
CMGC_MAPK_JNK_MAPK8_ST	Q9H211	CDT1	P45983	MAPK8	T82	A85S	85	Missense	distal	3	no	8.851	8.833	EPSD	GDSC;CCLE	2.638	Down-regulation
CMGC_MAPK_JNK_MAPK8_ST	Q9H211	CDT1	P45983	MAPK8	T82	T82P	82	Missense	central	0	yes	8.851	0.000	EPSD	GDSC	2.638	Loss
CMGC_MAPK_JNK_MAPK8_ST	Q9H211	CDT1	P45983	MAPK8	T82	P83L	83	Missense	proximal	1	no	8.851	1.279	EPSD	GDSC	2.638	Loss
CMGC_MAPK_JNK_MAPK8_ST	Q9H211	CDT1	P45983	MAPK8	S93	A90D	90	Missense	distal	-3	no	7.852	7.630	EPSD	GDSC;CCLE	2.638	Down-regulation
CMGC_MAPK_JNK_MAPK8_ST	Q9H211	CDT1	P45983	MAPK8	T152	R158H	158	Missense	distal	6	no	7.438	7.450	EPSD	GDSC	2.638	Up-regulation
CMGC_MAPK_JNK_MAPK8_ST	Q9H211	CDT1	P45983	MAPK8	T213	T213K	213	Missense	central	0	yes	9.762	0.000	EPSD	GDSC;CCLE	2.638	Loss
CMGC_MAPK_JNK_MAPK8_ST	Q9H211	CDT1	P45983	MAPK8	S318	L314M	314	Missense	distal	-4	no	8.942	9.016	EPSD	GDSC	2.638	Up-regulation
CMGC_MAPK_JNK_MAPK8_ST	Q9H211	CDT1	P45983	MAPK8	S391	R396K	396	Missense	distal	5	no	7.295	7.204	EPSD;PhosphoSitePlus	GDSC	2.638	Down-regulation
CMGC_MAPK_JNK_MAPK8_ST	Q9H211	CDT1	P45983	MAPK8	S391	A388T	388	Missense	distal	-3	no	7.295	7.241	EPSD;PhosphoSitePlus	GDSC;CCLE	2.638	Down-regulation
CMGC_MAPK_JNK_MAPK8_ST	Q9H211	CDT1	P45983	MAPK8	S394	R396K	396	Missense	proximal	2	no	9.045	9.368	EPSD	GDSC	2.638	Up-regulation
CMGC_MAPK_JNK_MAPK8_ST	Q9H211	CDT1	P45983	MAPK8	S394	A388T	388	Missense	distal	-6	no	9.045	9.067	EPSD	GDSC;CCLE	2.638	Up-regulation
CMGC_MAPK_JNK_MAPK8_ST	Q9H211	CDT1	P45983	MAPK8	T402	R396K	396	Missense	distal	-6	no	8.894	8.728	EPSD;PhosphoSitePlus	GDSC	2.638	Down-regulation
CMGC_MAPK_JNK_MAPK8_ST	P15336	ATF2	P45983	MAPK8	T69	V63A	63	Missense	distal	-6	no	8.052	7.851	PhosphoSitePlus;EPSD	GDSC;CCLE	2.638	Down-regulation
CMGC_MAPK_JNK_MAPK8_ST	P15336	ATF2	P45983	MAPK8	S136	Q134H	134	Missense	proximal	-2	no	8.636	8.562	EPSD	GDSC;CCLE	2.638	Down-regulation
CMGC_MAPK_JNK_MAPK8_ST	P15336	ATF2	P45983	MAPK8	T325	H331L	331	Missense	distal	6	no	7.959	7.936	EPSD	GDSC;CCLE	2.638	Down-regulation
CMGC_MAPK_JNK_MAPK8_ST	P15336	ATF2	P45983	MAPK8	S328	H331L	331	Missense	distal	3	no	8.292	8.355	EPSD	GDSC;CCLE	2.638	Up-regulation
CMGC_MAPK_JNK_MAPK8_ST	P15336	ATF2	P45983	MAPK8	T333	H331L	331	Missense	proximal	-2	no	7.887	7.878	EPSD	GDSC;CCLE	2.638	Down-regulation
CMGC_MAPK_JNK_MAPK8_ST	P05067	APP	P45983	MAPK8	T381	H388Y	388	Missense	distal	7	no	7.538	7.579	EPSD	GDSC;CCLE	2.638	Up-regulation
CMGC_MAPK_JNK_MAPK8_ST	O43524	FOXO3	P45983	MAPK8	S280	Q275*	275	Missense	distal	-5	no	2.651	3.175	EPSD	GDSC	2.638	Up-regulation
CMGC_MAPK_JNK_MAPK8_ST	O43524	FOXO3	P45983	MAPK8	S325	V320I	320	Missense	distal	-5	no	8.338	8.017	EPSD	GDSC;CCLE	2.638	Down-regulation
CMGC_MAPK_JNK_MAPK8_ST	O43524	FOXO3	P45983	MAPK8	S402	M408V	408	Missense	distal	6	no	7.290	7.274	EPSD	GDSC;CCLE	2.638	Down-regulation
CMGC_MAPK_JNK_MAPK8_ST	O43524	FOXO3	P45983	MAPK8	S411	R410W	410	Missense	proximal	-1	no	2.727	2.723	EPSD	GDSC;CCLE	2.638	Down-regulation
CMGC_MAPK_JNK_MAPK8_ST	O43524	FOXO3	P45983	MAPK8	S411	M408V	408	Missense	distal	-3	no	2.727	2.658	EPSD	GDSC;CCLE	2.638	Down-regulation
CMGC_MAPK_JNK_MAPK8_ST	O43524	FOXO3	P45983	MAPK8	T450	P456L	456	Missense	distal	6	no	3.347	3.300	EPSD	GDSC	2.638	Down-regulation
CMGC_MAPK_JNK_MAPK8_ST	O43524	FOXO3	P45983	MAPK8	S574	V576A	576	Missense	proximal	2	no	8.089	8.407	PhosphoSitePlus	GDSC;CCLE	2.638	Up-regulation
CMGC_MAPK_JNK_MAPK8_ST	P10276	RARA	P45983	MAPK8	S74	P78L	78	Missense	distal	4	no	7.189	6.782	EPSD	GDSC;CCLE	2.638	Down-regulation
CMGC_MAPK_JNK_MAPK8_ST	P10276	RARA	P45983	MAPK8	S77	P78L	78	Missense	proximal	1	no	7.003	-0.570	EPSD	GDSC;CCLE	2.638	Loss
CMGC_MAPK_JNK_MAPK8_ST	O43521	BCL2L11	P45983	MAPK8	S59	G62V	62	Missense	distal	3	no	8.407	8.463	EPSD	GDSC;CCLE	2.638	Up-regulation
CMGC_MAPK_JNK_MAPK8_ST	O43521	BCL2L11	P45983	MAPK8	S69	G62V	62	Missense	distal	-7	no	7.830	7.835	EPSD	GDSC;CCLE	2.638	Up-regulation
CMGC_MAPK_JNK_MAPK8_ST	O43521	BCL2L11	P45983	MAPK8	S104	A106P	106	Missense	proximal	2	no	9.184	8.975	EPSD	GDSC;CCLE	2.638	Down-regulation
CMGC_MAPK_JNK_MAPK8_ST	P38936	CDKN1A	P45983	MAPK8	T57	E56*	56	Missense	proximal	-1	no	6.619	6.573	EPSD;PhosphoSitePlus	GDSC	2.638	Down-regulation
CMGC_MAPK_JNK_MAPK8_ST	P54259	ATN1	P45983	MAPK8	S34	S29L	29	Missense	distal	-5	no	6.566	7.038	EPSD	GDSC	2.638	Up-regulation
CMGC_MAPK_JNK_MAPK8_ST	P54259	ATN1	P45983	MAPK8	S43	S50Y	50	Missense	distal	7	no	3.082	3.175	EPSD	GDSC;CCLE	2.638	Up-regulation
CMGC_MAPK_JNK_MAPK8_ST	P54259	ATN1	P45983	MAPK8	S43	K49T	49	Missense	distal	6	no	3.082	3.061	EPSD	GDSC;CCLE	2.638	Down-regulation
CMGC_MAPK_JNK_MAPK8_ST	P54259	ATN1	P45983	MAPK8	T64	R58*	58	Missense	distal	-6	no	7.457	7.537	EPSD	GDSC	2.638	Up-regulation
CMGC_MAPK_JNK_MAPK8_ST	P54259	ATN1	P45983	MAPK8	S168	P162R	162	Missense	distal	-6	no	7.914	7.980	EPSD	GDSC;CCLE	2.638	Up-regulation
CMGC_MAPK_JNK_MAPK8_ST	P54259	ATN1	P45983	MAPK8	S174	R177*	177	Missense	distal	3	no	2.737	2.848	EPSD	GDSC	2.638	Up-regulation
CMGC_MAPK_JNK_MAPK8_ST	P54259	ATN1	P45983	MAPK8	T175	R177*	177	Missense	proximal	2	no	7.233	7.103	EPSD	GDSC	2.638	Down-regulation
CMGC_MAPK_JNK_MAPK8_ST	P54259	ATN1	P45983	MAPK8	T630	P633S	633	Missense	distal	3	no	2.902	2.777	EPSD	GDSC;CCLE	2.638	Down-regulation
CMGC_MAPK_JNK_MAPK8_ST	P54259	ATN1	P45983	MAPK8	S632	P633S	633	Missense	proximal	1	no	8.266	0.538	EPSD	GDSC;CCLE	2.638	Loss
CMGC_MAPK_JNK_MAPK8_ST	P54259	ATN1	P45983	MAPK8	S645	A643D	643	Missense	proximal	-2	no	8.385	8.310	EPSD	GDSC;CCLE	2.638	Down-regulation
CMGC_MAPK_JNK_MAPK8_ST	P22736	NR4A1	P45983	MAPK8	T27	T27I	27	Missense	central	0	yes	7.733	0.000	EPSD	GDSC;CCLE	2.638	Loss
CMGC_MAPK_JNK_MAPK8_ST	P22736	NR4A1	P45983	MAPK8	T27	D24E	24	Missense	distal	-3	no	7.733	7.972	EPSD	GDSC;CCLE	2.638	Up-regulation
CMGC_MAPK_JNK_MAPK8_ST	P22736	NR4A1	P45983	MAPK8	S95	P96R	96	Missense	proximal	1	no	8.503	1.367	PhosphoSitePlus	GDSC;CCLE	2.638	Loss
CMGC_MAPK_JNK_MAPK8_ST	P22736	NR4A1	P45983	MAPK8	S152	L151V	151	Missense	proximal	-1	no	7.205	7.200	EPSD	GDSC;CCLE	2.638	Down-regulation
CMGC_MAPK_JNK_MAPK8_ST	P22736	NR4A1	P45983	MAPK8	S199	S201T	201	Missense	proximal	2	no	8.422	8.426	EPSD	GDSC;CCLE	2.638	Up-regulation
CMGC_MAPK_JNK_MAPK8_ST	P22736	NR4A1	P45983	MAPK8	S205	S201T	201	Missense	distal	-4	no	7.038	6.823	EPSD	GDSC;CCLE	2.638	Down-regulation
CMGC_MAPK_JNK_MAPK8_ST	P19793	RXRA	P45983	MAPK8	S21	R25*	25	Missense	distal	4	no	9.786	9.594	EPSD	GDSC	2.638	Down-regulation
CMGC_MAPK_JNK_MAPK8_ST	P19793	RXRA	P45983	MAPK8	S21	P22L	22	Missense	proximal	1	no	9.786	2.214	EPSD	GDSC	2.638	Loss
CMGC_MAPK_JNK_MAPK8_ST	O43379	WDR62	P45983	MAPK8	S445	S445N	445	Missense	central	0	yes	7.764	0.000	EPSD	GDSC;CCLE	2.638	Loss
CMGC_MAPK_JNK_MAPK8_ST	O43379	WDR62	P45983	MAPK8	S445	R438C	438	Missense	distal	-7	no	7.764	7.762	EPSD	GDSC;CCLE	2.638	Down-regulation
CMGC_MAPK_JNK_MAPK8_ST	O43379	WDR62	P45983	MAPK8	S445	S445R	445	Missense	central	0	yes	7.764	0.000	EPSD	GDSC;CCLE	2.638	Loss
CMGC_MAPK_JNK_MAPK8_ST	O43379	WDR62	P45983	MAPK8	T814	E809K	809	Missense	distal	-5	no	6.072	5.995	EPSD	GDSC	2.638	Down-regulation
CMGC_MAPK_JNK_MAPK8_ST	O43379	WDR62	P45983	MAPK8	S982	P983R	983	Missense	proximal	1	no	8.302	1.166	EPSD	GDSC;CCLE	2.638	Loss
CMGC_MAPK_JNK_MAPK8_ST	O43379	WDR62	P45983	MAPK8	S987	P983R	983	Missense	distal	-4	no	6.571	6.434	EPSD	GDSC;CCLE	2.638	Down-regulation
CMGC_MAPK_JNK_MAPK8_ST	O43379	WDR62	P45983	MAPK8	T1053	L1060P	1060	Missense	distal	7	no	7.656	7.617	PhosphoSitePlus	GDSC;CCLE	2.638	Down-regulation
CMGC_MAPK_JNK_MAPK8_ST	O43379	WDR62	P45983	MAPK8	S1070	E1065A	1065	Missense	distal	-5	no	7.122	7.124	EPSD	GDSC	2.638	Up-regulation
CMGC_MAPK_JNK_MAPK8_ST	O43379	WDR62	P45983	MAPK8	S1070	E1065D	1065	Missense	distal	-5	no	7.122	7.365	EPSD	GDSC;CCLE	2.638	Up-regulation
CMGC_MAPK_JNK_MAPK8_ST	P08047	SP1	P45983	MAPK8	S59	A66G	66	Missense	distal	7	no	10.071	10.130	EPSD	GDSC;CCLE	2.638	Up-regulation
CMGC_MAPK_JNK_MAPK8_ST	P08047	SP1	P45983	MAPK8	S73	A66G	66	Missense	distal	-7	no	8.822	8.836	EPSD	GDSC;CCLE	2.638	Up-regulation
CMGC_MAPK_JNK_MAPK8_ST	P08047	SP1	P45983	MAPK8	T737	T737A	737	Missense	central	0	yes	2.815	0.000	EPSD	GDSC	2.638	Loss
CMGC_MAPK_JNK_MAPK8_ST	P08047	SP1	P45983	MAPK8	T737	G736V	736	Missense	proximal	-1	no	2.815	2.806	EPSD	GDSC;CCLE	2.638	Down-regulation
CMGC_MAPK_JNK_MAPK8_ST	P08047	SP1	P45983	MAPK8	T737	A738T	738	Missense	proximal	1	no	2.815	2.176	EPSD	GDSC;CCLE	2.638	Loss
CMGC_MAPK_JNK_MAPK8_ST	P08047	SP1	P45983	MAPK8	T739	T737A	737	Missense	proximal	-2	no	9.677	9.707	EPSD;PhosphoSitePlus	GDSC	2.638	Up-regulation
CMGC_MAPK_JNK_MAPK8_ST	P08047	SP1	P45983	MAPK8	T739	G736V	736	Missense	distal	-3	no	9.677	9.565	EPSD;PhosphoSitePlus	GDSC;CCLE	2.638	Down-regulation
CMGC_MAPK_JNK_MAPK8_ST	P49023	PXN	P45983	MAPK8	S85	S83F	83	Missense	proximal	-2	no	7.393	7.278	EPSD	GDSC	2.638	Down-regulation
CMGC_MAPK_JNK_MAPK8_ST	P49023	PXN	P45983	MAPK8	S85	V87E	87	Missense	proximal	2	no	7.393	7.749	EPSD	GDSC	2.638	Up-regulation
CMGC_MAPK_JNK_MAPK8_ST	P49023	PXN	P45983	MAPK8	S126	P129L	129	Missense	distal	3	no	2.622	2.724	EPSD	GDSC	2.638	Gain
CMGC_MAPK_JNK_MAPK8_ST	P49023	PXN	P45983	MAPK8	S130	P129L	129	Missense	proximal	-1	no	8.678	8.659	EPSD	GDSC	2.638	Down-regulation
CMGC_MAPK_JNK_MAPK8_ST	P49023	PXN	P45983	MAPK8	S188	G191R	191	Missense	distal	3	no	9.041	9.034	EPSD	GDSC;CCLE	2.638	Down-regulation
CMGC_MAPK_JNK_MAPK8_ST	P49023	PXN	P45983	MAPK8	S188	S188R	188	Missense	central	0	yes	9.041	0.000	EPSD	GDSC	2.638	Loss
CMGC_MAPK_JNK_MAPK8_ST	P49023	PXN	P45983	MAPK8	S303	R301G	301	Missense	proximal	-2	no	7.429	7.442	EPSD	GDSC	2.638	Up-regulation
CMGC_MAPK_JNK_MAPK8_ST	P49023	PXN	P45983	MAPK8	S303	S302G	302	Missense	proximal	-1	no	7.429	7.405	EPSD	GDSC	2.638	Down-regulation
CMGC_MAPK_JNK_MAPK8_ST	P49023	PXN	P45983	MAPK8	S303	G305R	305	Missense	proximal	2	no	7.429	7.390	EPSD	GDSC	2.638	Down-regulation
CMGC_MAPK_JNK_MAPK8_ST	P49023	PXN	P45983	MAPK8	S321	S321N	321	Missense	central	0	yes	2.663	0.000	EPSD	GDSC;CCLE	2.638	Loss
CMGC_MAPK_JNK_MAPK8_ST	P49023	PXN	P45983	MAPK8	S322	S321N	321	Missense	proximal	-1	no	7.138	7.110	EPSD	GDSC;CCLE	2.638	Down-regulation
CMGC_MAPK_JNK_MAPK8_ST	Q9UQF2	MAPK8IP1	P45983	MAPK8	S235	D234N	234	Missense	proximal	-1	no	9.188	9.174	EPSD	GDSC	2.638	Down-regulation
CMGC_MAPK_JNK_MAPK8_ST	Q9UQF2	MAPK8IP1	P45983	MAPK8	T284	A277T	277	Missense	distal	-7	no	7.758	7.759	EPSD	GDSC	2.638	Up-regulation
CMGC_MAPK_JNK_MAPK8_ST	Q9UQF2	MAPK8IP1	P45983	MAPK8	S421	D414E	414	Missense	distal	-7	no	7.986	7.978	EPSD	GDSC;CCLE	2.638	Down-regulation
CMGC_MAPK_JNK_MAPK8_ST	Q9UQF2	MAPK8IP1	P45983	MAPK8	T448	E451K	451	Missense	distal	3	no	9.114	9.060	EPSD	GDSC;CCLE	2.638	Down-regulation
CMGC_MAPK_JNK_MAPK8_ST	Q07817	BCL2L1	P45983	MAPK8	T47	S43L	43	Missense	distal	-4	no	7.989	6.997	PhosphoSitePlus;EPSD	GDSC;CCLE	2.638	Down-regulation
CMGC_MAPK_JNK_MAPK8_ST	Q07817	BCL2L1	P45983	MAPK8	S62	P55S	55	Missense	distal	-7	no	6.612	6.606	EPSD;PhosphoSitePlus	GDSC;CCLE	2.638	Down-regulation
CMGC_MAPK_JNK_MAPK8_ST	Q07817	BCL2L1	P45983	MAPK8	S62	T69I	69	Missense	distal	7	no	6.612	6.645	EPSD;PhosphoSitePlus	GDSC;CCLE	2.638	Up-regulation
CMGC_MAPK_JNK_MAPK8_ST	Q07817	BCL2L1	P45983	MAPK8	S62	G67V	67	Missense	distal	5	no	6.612	6.625	EPSD;PhosphoSitePlus	GDSC;CCLE	2.638	Up-regulation
CMGC_MAPK_JNK_MAPK8_ST	O43561	LAT	P45983	MAPK8	S41	D42N	42	Missense	proximal	1	no	2.753	0.694	EPSD	GDSC;CCLE	2.638	Loss
CMGC_MAPK_JNK_MAPK8_ST	O43561	LAT	P45983	MAPK8	S209	A212V	212	Missense	distal	3	no	2.910	3.138	EPSD	GDSC	2.638	Up-regulation
CMGC_MAPK_JNK_MAPK8_ST	O43561	LAT	P45983	MAPK8	S209	L214R	214	Missense	distal	5	no	2.910	2.901	EPSD	GDSC	2.638	Down-regulation
CMGC_MAPK_JNK_MAPK8_ST	P42226	STAT6	P45983	MAPK8	S498	R495L	495	Missense	distal	-3	no	3.007	2.970	EPSD	GDSC;CCLE	2.638	Down-regulation
CMGC_MAPK_JNK_MAPK8_ST	P42226	STAT6	P45983	MAPK8	S498	K504T	504	Missense	distal	6	no	3.007	2.986	EPSD	GDSC	2.638	Down-regulation
CMGC_MAPK_JNK_MAPK8_ST	Q14934	NFATC4	P45983	MAPK8	S237	S237N	237	Missense	central	0	yes	7.383	0.000	EPSD	GDSC	2.638	Loss
CMGC_MAPK_JNK_MAPK8_ST	P17535	JUND	P45983	MAPK8	T117	S120N	120	Missense	distal	3	no	6.524	6.728	EPSD	GDSC	2.638	Up-regulation
CMGC_MAPK_JNK_MAPK8_ST	P17535	JUND	P45983	MAPK8	S259	S255T	255	Missense	distal	-4	no	8.532	8.318	EPSD	GDSC	2.638	Down-regulation
CMGC_MAPK_JNK_MAPK8_ST	P85298	ARHGAP8	P45983	MAPK8	T206	T206K	206	Missense	central	0	yes	8.983	0.000	EPSD	GDSC;CCLE	2.638	Loss
CMGC_MAPK_JNK_MAPK8_ST	P85298	ARHGAP8	P45983	MAPK8	T206	R205W	205	Missense	proximal	-1	no	8.983	8.979	EPSD	GDSC;CCLE	2.638	Down-regulation
CMGC_MAPK_JNK_MAPK8_ST	P85298	ARHGAP8	P45983	MAPK8	T212	T206K	206	Missense	distal	-6	no	6.469	6.432	EPSD	GDSC;CCLE	2.638	Down-regulation
CMGC_MAPK_JNK_MAPK8_ST	P85298	ARHGAP8	P45983	MAPK8	T212	R205W	205	Missense	distal	-7	no	6.469	6.472	EPSD	GDSC;CCLE	2.638	Up-regulation
CMGC_MAPK_JNK_MAPK8_ST	P10415	BCL2	P45983	MAPK8	T56	P59T	59	Missense	distal	3	no	9.128	9.030	EPSD	GDSC;CCLE	2.638	Down-regulation
CMGC_MAPK_JNK_MAPK8_ST	P10415	BCL2	P45983	MAPK8	T56	H55P	55	Missense	proximal	-1	no	9.128	9.138	EPSD	GDSC;CCLE	2.638	Up-regulation
CMGC_MAPK_JNK_MAPK8_ST	Q9Y6Q9	NCOA3	P45983	MAPK8	S101	Q96R	96	Missense	distal	-5	no	2.447	2.762	EPSD	GDSC;CCLE	2.638	Gain
CMGC_MAPK_JNK_MAPK8_ST	Q9Y6Q9	NCOA3	P45983	MAPK8	S465	P467Q	467	Missense	proximal	2	no	7.105	7.223	EPSD	GDSC	2.638	Up-regulation
CMGC_MAPK_JNK_MAPK8_ST	Q9Y6Q9	NCOA3	P45983	MAPK8	S465	Y459H	459	Missense	distal	-6	no	7.105	7.006	EPSD	GDSC;CCLE	2.638	Down-regulation
CMGC_MAPK_JNK_MAPK8_ST	Q9Y6Q9	NCOA3	P45983	MAPK8	S470	P467Q	467	Missense	distal	-3	no	8.539	8.596	EPSD	GDSC	2.638	Up-regulation
CMGC_MAPK_JNK_MAPK8_ST	Q9Y6Q9	NCOA3	P45983	MAPK8	S640	P641S	641	Missense	proximal	1	no	8.093	0.365	EPSD	GDSC;CCLE	2.638	Loss
CMGC_MAPK_JNK_MAPK8_ST	Q9Y6Q9	NCOA3	P45983	MAPK8	S655	S657F	657	Missense	proximal	2	no	6.793	6.521	EPSD	GDSC;CCLE	2.638	Down-regulation
CMGC_MAPK_JNK_MAPK8_ST	Q9Y6Q9	NCOA3	P45983	MAPK8	S728	V721I	721	Missense	distal	-7	no	9.493	9.484	EPSD	GDSC	2.638	Down-regulation
CMGC_MAPK_JNK_MAPK8_ST	Q9Y6Q9	NCOA3	P45983	MAPK8	T914	S917L	917	Missense	distal	3	no	8.452	8.679	EPSD	GDSC	2.638	Up-regulation
CMGC_MAPK_JNK_MAPK8_ST	Q15672	TWIST1	P45983	MAPK8	S99	E104Q	104	Missense	distal	5	no	8.122	8.153	EPSD	GDSC;CCLE	2.638	Up-regulation
CMGC_MAPK_JNK_MAPK8_ST	Q9UGP4	LIMD1	P45983	MAPK8	S197	G195R	195	Missense	proximal	-2	no	8.126	8.113	EPSD	GDSC;CCLE	2.638	Down-regulation
CMGC_MAPK_JNK_MAPK8_ST	Q9UGP4	LIMD1	P45983	MAPK8	T294	V290F	290	Missense	distal	-4	no	7.586	7.681	EPSD	GDSC;CCLE	2.638	Up-regulation
CMGC_MAPK_JNK_MAPK8_ST	Q99607	ELF4	P45983	MAPK8	S194	P196L	196	Missense	proximal	2	no	2.695	2.618	EPSD	GDSC;CCLE	2.638	Loss
CMGC_MAPK_JNK_MAPK8_ST	P05412	JUN	P45983	MAPK8	T91	H87R	87	Missense	distal	-4	no	8.328	8.270	EPSD;PhosphoSitePlus	GDSC;CCLE	2.638	Down-regulation
CMGC_MAPK_JNK_MAPK8_ST	P05412	JUN	P45983	MAPK8	T93	H87R	87	Missense	distal	-6	no	8.490	8.511	EPSD;PhosphoSitePlus	GDSC;CCLE	2.638	Up-regulation
CMGC_MAPK_JNK_MAPK8_ST	P05412	JUN	P45983	MAPK8	T239	E234D	234	Missense	distal	-5	no	5.188	5.430	EPSD	GDSC;CCLE	2.638	Up-regulation
CMGC_MAPK_JNK_MAPK8_ST	Q14451	GRB7	P45983	MAPK8	S6	D4N	4	Missense	proximal	-2	no	8.652	8.555	EPSD	GDSC;CCLE	2.638	Down-regulation
CMGC_MAPK_JNK_MAPK8_ST	Q14451	GRB7	P45983	MAPK8	T23	P21L	21	Missense	proximal	-2	no	7.643	7.450	EPSD	GDSC;CCLE	2.638	Down-regulation
CMGC_MAPK_JNK_MAPK8_ST	Q14451	GRB7	P45983	MAPK8	T27	T33P	33	Missense	distal	6	no	7.100	7.079	EPSD	GDSC	2.638	Down-regulation
CMGC_MAPK_JNK_MAPK8_ST	Q14451	GRB7	P45983	MAPK8	T27	P21L	21	Missense	distal	-6	no	7.100	7.191	EPSD	GDSC;CCLE	2.638	Up-regulation
CMGC_MAPK_JNK_MAPK8_ST	Q14451	GRB7	P45983	MAPK8	T33	T33P	33	Missense	central	0	yes	6.076	0.000	EPSD	GDSC	2.638	Loss
CMGC_MAPK_JNK_MAPK8_ST	Q14451	GRB7	P45983	MAPK8	S76	P77H	77	Missense	proximal	1	no	7.552	-0.364	EPSD	GDSC;CCLE	2.638	Loss
CMGC_MAPK_JNK_MAPK8_ST	Q14451	GRB7	P45983	MAPK8	S81	G85R	85	Missense	distal	4	no	8.724	8.703	EPSD	GDSC	2.638	Down-regulation
CMGC_MAPK_JNK_MAPK8_ST	Q14451	GRB7	P45983	MAPK8	S81	P77H	77	Missense	distal	-4	no	8.724	8.645	EPSD	GDSC;CCLE	2.638	Down-regulation
CMGC_MAPK_JNK_MAPK8_ST	Q14451	GRB7	P45983	MAPK8	T142	V146L	146	Missense	distal	4	no	2.619	2.706	EPSD	GDSC	2.638	Gain
CMGC_MAPK_JNK_MAPK8_ST	P30305	CDC25B	P45983	MAPK8	S117	A124S	124	Missense	distal	7	no	7.637	7.631	EPSD	GDSC;CCLE	2.638	Down-regulation
CMGC_MAPK_JNK_MAPK8_ST	P30305	CDC25B	P45983	MAPK8	S160	V154A	154	Missense	distal	-6	no	7.307	7.106	EPSD	GDSC	2.638	Down-regulation
CMGC_MAPK_JNK_MAPK8_ST	P30305	CDC25B	P45983	MAPK8	S188	E193Q	193	Missense	distal	5	no	3.282	3.313	EPSD	GDSC;CCLE	2.638	Up-regulation
CMGC_MAPK_JNK_MAPK8_ST	P30305	CDC25B	P45983	MAPK8	T344	D343N	343	Missense	proximal	-1	no	5.844	5.829	EPSD	GDSC;CCLE	2.638	Down-regulation
CMGC_MAPK_JNK_MAPK8_ST	Q07820	MCL1	P45983	MAPK8	S121	M120V	120	Missense	proximal	-1	no	6.612	6.603	EPSD;PhosphoSitePlus	GDSC	2.638	Down-regulation
CMGC_MAPK_JNK_MAPK8_ST	P30307	CDC25C	P45983	MAPK8	S247	G248D	248	Missense	proximal	1	no	2.872	3.504	EPSD	GDSC	2.638	Up-regulation
CMGC_MAPK_JNK_MAPK8_ST	P30307	CDC25C	P45983	MAPK8	S472	M471T	471	Missense	proximal	-1	no	6.406	6.433	EPSD	GDSC;CCLE	2.638	Up-regulation
CMGC_MAPK_JNK_MAPK8_ST	Q8N122	RPTOR	P45983	MAPK8	S696	L694F	694	Missense	proximal	-2	no	7.020	6.992	PhosphoSitePlus;EPSD	GDSC;CCLE	2.638	Down-regulation
CMGC_MAPK_JNK_MAPK8_ST	Q8N122	RPTOR	P45983	MAPK8	S711	R716I	716	Missense	distal	5	no	6.618	6.594	EPSD	GDSC;CCLE	2.638	Down-regulation
CMGC_MAPK_JNK_MAPK8_ST	Q8N122	RPTOR	P45983	MAPK8	S711	R718H	718	Missense	distal	7	no	6.618	6.607	EPSD	GDSC;CCLE	2.638	Down-regulation
CMGC_MAPK_JNK_MAPK8_ST	Q8N122	RPTOR	P45983	MAPK8	T714	R716I	716	Missense	proximal	2	no	8.846	8.965	EPSD	GDSC;CCLE	2.638	Up-regulation
CMGC_MAPK_JNK_MAPK8_ST	Q8N122	RPTOR	P45983	MAPK8	T714	R718H	718	Missense	distal	4	no	8.846	8.883	EPSD	GDSC;CCLE	2.638	Up-regulation
CMGC_MAPK_JNK_MAPK8_ST	Q8N122	RPTOR	P45983	MAPK8	S877	S881P	881	Missense	distal	4	no	9.094	9.069	EPSD	GDSC;CCLE	2.638	Down-regulation
CMGC_MAPK_JNK_MAPK8_ST	Q8N122	RPTOR	P45983	MAPK8	S881	S881P	881	Missense	central	0	yes	3.451	0.000	EPSD	GDSC;CCLE	2.638	Loss
CMGC_MAPK_JNK_MAPK8_ST	Q8N122	RPTOR	P45983	MAPK8	T917	Y916H	916	Missense	proximal	-1	no	6.949	6.966	EPSD	GDSC;CCLE	2.638	Up-regulation
CMGC_MAPK_JNK_MAPK8_ST	P04637	TP53	P45983	MAPK8	S33	Q38*	38	Missense	distal	5	no	7.176	7.262	EPSD	GDSC	2.638	Up-regulation
CMGC_MAPK_JNK_MAPK8_ST	P04637	TP53	P45983	MAPK8	S127	Y126*	126	Missense	proximal	-1	no	8.358	8.353	EPSD	GDSC	2.638	Down-regulation
CMGC_MAPK_JNK_MAPK8_ST	P04637	TP53	P45983	MAPK8	S127	K120*	120	Missense	distal	-7	no	8.358	8.384	EPSD	GDSC	2.638	Up-regulation
CMGC_MAPK_JNK_MAPK8_ST	P04637	TP53	P45983	MAPK8	T150	Q144*	144	Missense	distal	-6	no	6.536	6.719	EPSD	GDSC	2.638	Up-regulation
CMGC_MAPK_JNK_MAPK8_ST	P04637	TP53	P45983	MAPK8	T150	W146*	146	Missense	distal	-4	no	6.536	6.313	EPSD	GDSC	2.638	Down-regulation
CMGC_MAPK_JNK_MAPK8_ST	P04637	TP53	P45983	MAPK8	S183	S183*	183	Missense	central	0	yes	3.143	0.000	EPSD	GDSC	2.638	Loss
CMGC_MAPK_JNK_MAPK8_ST	P04637	TP53	P45983	MAPK8	S183	E180*	180	Missense	distal	-3	no	3.143	2.598	EPSD	GDSC	2.638	Loss
CMGC_MAPK_JNK_MAPK8_ST	P04637	TP53	P45983	MAPK8	S315	Q317*	317	Missense	proximal	2	no	8.332	8.027	EPSD	GDSC	2.638	Down-regulation
CMGC_MAPK_JNK_MAPK8_ST	P04637	TP53	P45983	MAPK8	S315	K319*	319	Missense	distal	4	no	8.332	7.745	EPSD	GDSC	2.638	Down-regulation
CMGC_MAPK_JNK_MAPK8_ST	Q96FI4	NEIL1	P45983	MAPK8	S306	P307H	307	Missense	proximal	1	no	8.823	0.907	EPSD;PhosphoSitePlus	GDSC;CCLE	2.638	Loss
CMGC_MAPK_JNK_MAPK8_ST	Q96FI4	NEIL1	P45983	MAPK8	S306	K299*	299	Missense	distal	-7	no	8.823	8.849	EPSD;PhosphoSitePlus	GDSC	2.638	Up-regulation
CMGC_MAPK_JNK_MAPK8_ST	P37231	PPARG	P45983	MAPK8	S112	S112C	112	Missense	central	0	yes	8.805	0.000	PhosphoSitePlus	GDSC;CCLE	2.638	Loss
CMGC_MAPK_JNK_MAPK8_ST	Q96LC9	BMF	P45983	MAPK8	S74	Q80K	80	Missense	distal	6	no	7.205	7.237	PhosphoSitePlus	GDSC;CCLE	2.638	Up-regulation
CMGC_MAPK_JNK_MAPK8_ST	Q96LC9	BMF	P45983	MAPK8	S77	Q80K	80	Missense	distal	3	no	8.228	8.131	EPSD	GDSC;CCLE	2.638	Down-regulation
CMGC_MAPK_JNK_MAPK8_ST	Q7KZF4	SND1	P45983	MAPK8	T98	P104L	104	Missense	distal	6	no	3.055	3.008	EPSD	GDSC;CCLE	2.638	Down-regulation
CMGC_MAPK_JNK_MAPK8_ST	Q7KZF4	SND1	P45983	MAPK8	T103	P104L	104	Missense	proximal	1	no	8.214	0.641	PhosphoSitePlus	GDSC;CCLE	2.638	Loss
CMGC_MAPK_JNK_MAPK8_ST	Q7KZF4	SND1	P45983	MAPK8	T179	R184G	184	Missense	distal	5	no	3.146	3.143	EPSD	GDSC;CCLE	2.638	Down-regulation
CMGC_MAPK_JNK_MAPK8_ST	Q7KZF4	SND1	P45983	MAPK8	T240	T240A	240	Missense	central	0	yes	7.851	0.000	EPSD	GDSC;CCLE	2.638	Loss
CMGC_MAPK_JNK_MAPK8_ST	Q7KZF4	SND1	P45983	MAPK8	S426	R423S	423	Missense	distal	-3	no	9.196	9.500	EPSD	GDSC;CCLE	2.638	Up-regulation
CMGC_MAPK_JNK_MAPK8_ST	Q7KZF4	SND1	P45983	MAPK8	S426	E430D	430	Missense	distal	4	no	9.196	9.044	EPSD	GDSC;CCLE	2.638	Down-regulation
CMGC_MAPK_JNK_MAPK8_ST	Q7KZF4	SND1	P45983	MAPK8	S645	A650V	650	Missense	distal	5	no	2.761	2.834	EPSD	GDSC;CCLE	2.638	Up-regulation
CMGC_MAPK_JNK_MAPK8_ST	Q7KZF4	SND1	P45983	MAPK8	S781	G778C	778	Missense	distal	-3	no	8.561	8.587	EPSD	GDSC;CCLE	2.638	Up-regulation
CMGC_MAPK_JNK_MAPK8_ST	P05787	KRT8	P45983	MAPK8	S13	T6S	6	Missense	distal	-7	no	2.739	2.737	EPSD	GDSC;CCLE	2.638	Down-regulation
CMGC_MAPK_JNK_MAPK8_ST	P05787	KRT8	P45983	MAPK8	S74	L76R	76	Missense	proximal	2	no	7.728	7.748	PhosphoSitePlus;EPSD	GDSC;CCLE	2.638	Up-regulation
CMGC_MAPK_JNK_MAPK8_ST	P05787	KRT8	P45983	MAPK8	S417	T416A	416	Missense	proximal	-1	no	2.996	2.997	EPSD	GDSC;CCLE	2.638	Up-regulation
CMGC_MAPK_JNK_MAPK8_ST	P05787	KRT8	P45983	MAPK8	S417	G421A	421	Missense	distal	4	no	2.996	3.339	EPSD	GDSC	2.638	Up-regulation
CMGC_MAPK_JNK_MAPK8_ST	P14618	PKM	P45983	MAPK8	S406	A402V	402	Missense	distal	-4	no	4.057	3.202	EPSD	GDSC;CCLE	2.638	Down-regulation
CMGC_MAPK_JNK_MAPK8_ST	O95644	NFATC1	P45983	MAPK8	S278	P275L	275	Missense	distal	-3	no	11.304	11.125	EPSD	GDSC	2.638	Down-regulation
CMGC_MAPK_JNK_MAPK8_ST	O95644	NFATC1	P45983	MAPK8	S282	P275L	275	Missense	distal	-7	no	9.467	9.479	EPSD	GDSC	2.638	Up-regulation
CMGC_MAPK_JNK_MAPK8_ST	Q96P20	NLRP3	P45983	MAPK8	S387	E380K	380	Missense	distal	-7	no	2.719	2.716	EPSD	GDSC;CCLE	2.638	Down-regulation
CMGC_MAPK_JNK_MAPK8_ST	Q96P20	NLRP3	P45983	MAPK8	S387	F383L	383	Missense	distal	-4	no	2.719	2.666	EPSD	GDSC;CCLE	2.638	Down-regulation
CMGC_MAPK_JNK_MAPK8_ST	P10275	AR	P45983	MAPK8	S516	E523D	523	Missense	distal	7	no	7.555	7.595	EPSD	GDSC	2.638	Up-regulation
CMGC_MAPK_JNK_MAPK8_ST	P35568	IRS1	P45983	MAPK8	S383	R381C	381	Missense	proximal	-2	no	7.254	7.268	EPSD	GDSC;CCLE	2.638	Up-regulation
CMGC_MAPK_JNK_MAPK8_ST	P35568	IRS1	P45983	MAPK8	S383	A386S	386	Missense	distal	3	no	7.254	7.236	EPSD	GDSC;CCLE	2.638	Down-regulation
CMGC_MAPK_JNK_MAPK8_ST	P35568	IRS1	P45983	MAPK8	S383	P376L	376	Missense	distal	-7	no	7.254	7.266	EPSD	GDSC;CCLE	2.638	Up-regulation
CMGC_MAPK_JNK_MAPK8_ST	P35568	IRS1	P45983	MAPK8	S388	R381C	381	Missense	distal	-7	no	6.604	6.602	EPSD	GDSC;CCLE	2.638	Down-regulation
CMGC_MAPK_JNK_MAPK8_ST	P35568	IRS1	P45983	MAPK8	S388	A386S	386	Missense	proximal	-2	no	6.604	6.549	EPSD	GDSC;CCLE	2.638	Down-regulation
CMGC_MAPK_JNK_MAPK8_ST	P35568	IRS1	P45983	MAPK8	S413	R411*	411	Missense	proximal	-2	no	3.042	2.967	EPSD	GDSC	2.638	Down-regulation
CMGC_MAPK_JNK_MAPK8_ST	P35568	IRS1	P45983	MAPK8	T495	G488S	488	Missense	distal	-7	no	8.034	8.021	EPSD	GDSC;CCLE	2.638	Down-regulation
CMGC_MAPK_JNK_MAPK8_ST	P35568	IRS1	P45983	MAPK8	S547	A546V	546	Missense	proximal	-1	no	2.753	2.718	EPSD	GDSC;CCLE	2.638	Down-regulation
CMGC_MAPK_JNK_MAPK8_ST	P35568	IRS1	P45983	MAPK8	S636	A642S	642	Missense	distal	6	no	6.770	6.773	EPSD	GDSC;CCLE	2.638	Up-regulation
CMGC_MAPK_JNK_MAPK8_ST	P35568	IRS1	P45983	MAPK8	S736	P737S	737	Missense	proximal	1	no	6.755	-0.973	EPSD	GDSC	2.638	Loss
CMGC_MAPK_JNK_MAPK8_ST	P35568	IRS1	P45983	MAPK8	S1078	S1084R	1084	Missense	distal	6	no	5.863	5.803	EPSD	GDSC	2.638	Down-regulation
CMGC_MAPK_JNK_MAPK8_ST	P35568	IRS1	P45983	MAPK8	S1078	A1085D	1085	Missense	distal	7	no	5.863	5.898	EPSD	GDSC;CCLE	2.638	Up-regulation
CMGC_MAPK_JNK_MAPK8_ST	P35568	IRS1	P45983	MAPK8	T1196	P1192L	1192	Missense	distal	-4	no	8.037	7.710	EPSD	GDSC;CCLE	2.638	Down-regulation
CMGC_MAPK_JNK_MAPK8_ST	P35568	IRS1	P45983	MAPK8	T1196	P1202S	1202	Missense	distal	6	no	8.037	8.062	EPSD	GDSC	2.638	Up-regulation
CMGC_MAPK_JNK_MAPK8_ST	P35568	IRS1	P45983	MAPK8	S1217	S1218P	1218	Missense	proximal	1	no	1.400	9.129	EPSD	GDSC	2.638	Gain
CMGC_MAPK_JNK_MAPK8_ST	P35568	IRS1	P45983	MAPK8	S1231	S1233N	1233	Missense	proximal	2	no	3.402	3.140	EPSD	GDSC;CCLE	2.638	Down-regulation
CMGC_MAPK_JNK_MAPK8_ST	Q15750	TAB1	P45983	MAPK8	S339	R333W	333	Missense	distal	-6	no	3.196	3.223	EPSD	GDSC;CCLE	2.638	Up-regulation
CMGC_MAPK_JNK_MAPK8_ST	P40763	STAT3	P45983	MAPK8	T714	C712Y	712	Missense	proximal	-2	no	8.025	7.960	EPSD	GDSC;CCLE	2.638	Down-regulation
CMGC_MAPK_JNK_MAPK8_ST	P63104	YWHAZ	P45983	MAPK8	S184	A188V	188	Missense	distal	4	no	9.105	8.586	PhosphoSitePlus	GDSC	2.638	Down-regulation
CMGC_MAPK_JNK_MAPK8_ST	P63104	YWHAZ	P45983	MAPK8	S184	Y178C	178	Missense	distal	-6	no	9.105	9.002	PhosphoSitePlus	GDSC;CCLE	2.638	Down-regulation
CMGC_MAPK_JNK_MAPK8_ST	P98177	FOXO4	P45983	MAPK8	T451	T458A	458	Missense	distal	7	no	7.800	7.798	EPSD;PhosphoSitePlus	GDSC;CCLE	2.638	Down-regulation
CMGC_MAPK_JNK_MAPK8_ST	P98177	FOXO4	P45983	MAPK8	T451	T455I	455	Missense	distal	4	no	7.800	7.659	EPSD;PhosphoSitePlus	GDSC;CCLE	2.638	Down-regulation
CMGC_MAPK_JNK_MAPK8_ST	P98177	FOXO4	P45983	MAPK8	T455	T458A	458	Missense	distal	3	no	8.305	8.295	PhosphoSitePlus;EPSD	GDSC;CCLE	2.638	Down-regulation
CMGC_MAPK_JNK_MAPK8_ST	P98177	FOXO4	P45983	MAPK8	T455	T455I	455	Missense	central	0	yes	8.305	0.000	PhosphoSitePlus;EPSD	GDSC;CCLE	2.638	Loss
CMGC_MAPK_JNK_MAPK8_ST	P31946	YWHAB	P45983	MAPK8	S60	A56P	56	Missense	distal	-4	no	3.202	2.714	EPSD	GDSC	2.638	Down-regulation
CMGC_MAPK_JNK_MAPK8_ST	Q9NPI6	DCP1A	P45983	MAPK8	T290	A297G	297	Missense	distal	7	no	7.257	7.316	EPSD	GDSC	2.638	Up-regulation
CMGC_MAPK_JNK_MAPK8_ST	Q9NPI6	DCP1A	P45983	MAPK8	T295	A297G	297	Missense	proximal	2	no	5.896	5.670	EPSD	GDSC	2.638	Down-regulation
CMGC_MAPK_JNK_MAPK8_ST	Q9NPI6	DCP1A	P45983	MAPK8	T348	T348M	348	Missense	central	0	yes	7.103	0.000	EPSD	GDSC;CCLE	2.638	Loss
CMGC_MAPK_JNK_MAPK8_ST	Q9NPI6	DCP1A	P45983	MAPK8	S353	T348M	348	Missense	distal	-5	no	7.247	7.688	EPSD	GDSC;CCLE	2.638	Up-regulation
CMGC_MAPK_JNK_MAPK8_ST	Q9NPI6	DCP1A	P45983	MAPK8	S373	Q372R	372	Missense	proximal	-1	no	7.578	7.558	EPSD	GDSC;CCLE	2.638	Down-regulation
CMGC_MAPK_JNK_MAPK8_ST	Q9NPI6	DCP1A	P45983	MAPK8	S373	S367T	367	Missense	distal	-6	no	7.578	7.603	EPSD	GDSC;CCLE	2.638	Up-regulation
CMGC_MAPK_JNK_MAPK8_ST	Q9NPI6	DCP1A	P45983	MAPK8	S422	G426D	426	Missense	distal	4	no	8.028	8.170	EPSD	GDSC	2.638	Up-regulation
CMGC_MAPK_JNK_MAPK8_ST	Q9NPI6	DCP1A	P45983	MAPK8	T430	G426D	426	Missense	distal	-4	no	6.351	6.673	EPSD	GDSC	2.638	Up-regulation
CMGC_MAPK_JNK_MAPK8_ST	Q9H2B2	SYT4	P45983	MAPK8	S135	E130G	130	Missense	distal	-5	no	9.420	9.814	PhosphoSitePlus	GDSC;CCLE	2.638	Up-regulation
CMGC_MAPK_JNK_MAPK8_ST	Q16621	NFE2	P45983	MAPK8	S346	S344R	344	Missense	proximal	-2	no	8.549	8.471	EPSD	GDSC;CCLE	2.638	Down-regulation
CAMK_CAMKL_MARK_MARK3_ST	Q06413	MEF2C	P27448	MARK3	S98	D102E	102	Missense	distal	4	no	283.062	282.491	EPSD	GDSC	255.132	Down-regulation
CAMK_CAMKL_MARK_MARK3_ST	Q06413	MEF2C	P27448	MARK3	S192	R189*	189	Missense	distal	-3	no	314.836	268.327	EPSD	GDSC	255.132	Down-regulation
CAMK_CAMKL_MARK_MARK3_ST	Q06413	MEF2C	P27448	MARK3	S222	R220*	220	Missense	proximal	-2	no	529.076	514.556	PhosphoSitePlus	GDSC	255.132	Down-regulation
CAMK_CAMKL_MARK_MARK3_ST	Q99689	FEZ1	P27448	MARK3	T136	E143V	143	Missense	distal	7	no	257.380	258.720	EPSD	GDSC;CCLE	255.132	Up-regulation
CAMK_CAMKL_MARK_MARK3_ST	Q92974	ARHGEF2	P27448	MARK3	S142	R141H	141	Missense	proximal	-1	no	286.251	287.051	EPSD	GDSC	255.132	Up-regulation
CAMK_CAMKL_MARK_MARK3_ST	Q92974	ARHGEF2	P27448	MARK3	S143	R141H	141	Missense	proximal	-2	no	373.920	358.120	EPSD	GDSC	255.132	Down-regulation
CAMK_CAMKL_MARK_MARK3_ST	P30307	CDC25C	P27448	MARK3	S38	E34Q	34	Missense	distal	-4	no	382.967	386.410	EPSD	GDSC;CCLE	255.132	Up-regulation
CAMK_CAMKL_MARK_MARK3_ST	P30307	CDC25C	P27448	MARK3	S247	G248D	248	Missense	proximal	1	no	296.754	296.755	EPSD	GDSC	255.132	Up-regulation
AGC_Akt_AKT2_ST	Q04656	ATP7A	P31751	AKT2	S360	Q364H	364	Missense	distal	4	no	21.226	21.416	EPSD	GDSC	19.022	Up-regulation
AGC_Akt_AKT2_ST	Q04656	ATP7A	P31751	AKT2	S639	R636Q	636	Missense	distal	-3	no	24.731	16.046	EPSD	GDSC;CCLE	19.022	Loss
AGC_Akt_AKT2_ST	Q04656	ATP7A	P31751	AKT2	S1424	S1417I	1417	Missense	distal	-7	no	26.368	26.941	PhosphoSitePlus;EPSD	GDSC;CCLE	19.022	Up-regulation
AGC_Akt_AKT2_ST	Q04656	ATP7A	P31751	AKT2	S1463	I1464V	1464	Missense	proximal	1	no	28.373	26.639	EPSD;PhosphoSitePlus	GDSC	19.022	Down-regulation
AGC_Akt_AKT2_ST	Q04656	ATP7A	P31751	AKT2	S1466	I1464V	1464	Missense	proximal	-2	no	28.475	30.490	EPSD;PhosphoSitePlus	GDSC	19.022	Up-regulation
AGC_Akt_AKT2_ST	Q13835	PKP1	P31751	AKT2	S142	G139S	139	Missense	distal	-3	no	24.069	24.679	EPSD	GDSC	19.022	Up-regulation
AGC_Akt_AKT2_ST	Q13835	PKP1	P31751	AKT2	S205	K198R	198	Missense	distal	-7	no	20.966	20.902	EPSD	GDSC;CCLE	19.022	Down-regulation
AGC_Akt_AKT2_ST	Q13835	PKP1	P31751	AKT2	S336	E333K	333	Missense	distal	-3	no	16.054	24.562	EPSD	GDSC;CCLE	19.022	Gain
AGC_Akt_AKT2_ST	Q99683	MAP3K5	P31751	AKT2	S83	S83C	83	Missense	central	0	yes	33.303	0.000	PhosphoSitePlus	GDSC;CCLE	19.022	Loss
AGC_Akt_AKT2_ST	Q99683	MAP3K5	P31751	AKT2	S763	G760R	760	Missense	distal	-3	no	17.340	27.067	EPSD	GDSC	19.022	Gain
AGC_Akt_AKT2_ST	Q99683	MAP3K5	P31751	AKT2	S906	H900Y	900	Missense	distal	-6	no	19.298	19.625	EPSD	GDSC;CCLE	19.022	Up-regulation
AGC_Akt_AKT2_ST	Q99683	MAP3K5	P31751	AKT2	T1059	D1063Y	1063	Missense	distal	4	no	25.919	25.963	EPSD	GDSC	19.022	Up-regulation
AGC_Akt_AKT2_ST	P00533	EGFR	P31751	AKT2	S229	N234D	234	Missense	distal	5	no	28.687	28.050	PhosphoSitePlus	GDSC;CCLE	19.022	Down-regulation
AGC_Akt_AKT2_ST	P00533	EGFR	P31751	AKT2	S695	Q701R	701	Missense	distal	6	no	18.385	19.172	EPSD	GDSC;CCLE	19.022	Gain
AGC_Akt_AKT2_ST	P00533	EGFR	P31751	AKT2	S1064	R1068*	1068	Missense	distal	4	no	19.237	19.643	EPSD	GDSC	19.022	Up-regulation
AGC_Akt_AKT2_ST	P15311	EZR	P31751	AKT2	T299	R293H	293	Missense	distal	-6	no	18.874	19.144	EPSD	GDSC;CCLE	19.022	Gain
AGC_Akt_AKT2_ST	P15311	EZR	P31751	AKT2	S535	R529W	529	Missense	distal	-6	no	20.541	21.356	EPSD	GDSC;CCLE	19.022	Up-regulation
AGC_Akt_AKT2_ST	Q92908	GATA6	P31751	AKT2	S24	F27L	27	Missense	distal	3	no	20.684	20.262	EPSD	GDSC;CCLE	19.022	Down-regulation
AGC_Akt_AKT2_ST	Q92908	GATA6	P31751	AKT2	S33	F27L	27	Missense	distal	-6	no	27.560	27.401	EPSD	GDSC;CCLE	19.022	Down-regulation
AGC_Akt_AKT2_ST	Q92908	GATA6	P31751	AKT2	S37	S44F	44	Missense	distal	7	no	21.620	20.580	EPSD	GDSC;CCLE	19.022	Down-regulation
AGC_Akt_AKT2_ST	Q14315	FLNC	P31751	AKT2	T423	V426M	426	Missense	distal	3	no	21.423	21.673	EPSD	GDSC;CCLE	19.022	Up-regulation
AGC_Akt_AKT2_ST	Q14315	FLNC	P31751	AKT2	S1545	G1548D	1548	Missense	distal	3	no	19.413	19.949	EPSD	GDSC;CCLE	19.022	Up-regulation
AGC_Akt_AKT2_ST	Q14315	FLNC	P31751	AKT2	S2146	R2142S	2142	Missense	distal	-4	no	18.990	19.232	EPSD	GDSC;CCLE	19.022	Gain
AGC_Akt_AKT2_ST	Q14315	FLNC	P31751	AKT2	T2179	L2174M	2174	Missense	distal	-5	no	19.607	8.818	EPSD	GDSC;CCLE	19.022	Loss
AGC_Akt_AKT2_ST	Q14315	FLNC	P31751	AKT2	T2179	R2173P	2173	Missense	distal	-6	no	19.607	20.249	EPSD	GDSC;CCLE	19.022	Up-regulation
AGC_Akt_AKT2_ST	Q14315	FLNC	P31751	AKT2	S2181	L2174M	2174	Missense	distal	-7	no	20.553	20.453	EPSD	GDSC;CCLE	19.022	Down-regulation
AGC_Akt_AKT2_ST	Q14315	FLNC	P31751	AKT2	S2233	R2230H	2230	Missense	distal	-3	no	35.073	15.264	PhosphoSitePlus	GDSC	19.022	Loss
AGC_Akt_AKT2_ST	Q14315	FLNC	P31751	AKT2	S2395	S2395N	2395	Missense	central	0	yes	19.748	0.000	EPSD	GDSC;CCLE	19.022	Loss
AGC_Akt_AKT2_ST	Q14315	FLNC	P31751	AKT2	S2624	R2621Q	2621	Missense	distal	-3	no	21.774	13.089	EPSD	GDSC	19.022	Loss
AGC_Akt_AKT2_ST	Q14315	FLNC	P31751	AKT2	S2626	R2621Q	2621	Missense	distal	-5	no	24.793	20.459	EPSD	GDSC	19.022	Down-regulation
AGC_Akt_AKT2_ST	P03372	ESR1	P31751	AKT2	S167	G160S	160	Missense	distal	-7	no	34.641	34.525	PhosphoSitePlus	GDSC	19.022	Down-regulation
AGC_Akt_AKT2_ST	P03372	ESR1	P31751	AKT2	S167	R164I	164	Missense	distal	-3	no	34.641	27.236	PhosphoSitePlus	GDSC;CCLE	19.022	Down-regulation
AGC_Akt_AKT2_ST	P03372	ESR1	P31751	AKT2	S236	R241L	241	Missense	distal	5	no	31.635	29.925	EPSD	GDSC;CCLE	19.022	Down-regulation
AGC_Akt_AKT2_ST	O43516	WIPF1	P31751	AKT2	S135	P130L	130	Missense	distal	-5	no	23.063	19.435	EPSD	GDSC;CCLE	19.022	Down-regulation
AGC_Akt_AKT2_ST	O43516	WIPF1	P31751	AKT2	T136	P130L	130	Missense	distal	-6	no	19.401	19.466	EPSD	GDSC;CCLE	19.022	Up-regulation
AGC_Akt_AKT2_ST	O43516	WIPF1	P31751	AKT2	S137	P130L	130	Missense	distal	-7	no	22.220	22.323	EPSD	GDSC;CCLE	19.022	Up-regulation
AGC_Akt_AKT2_ST	O43516	WIPF1	P31751	AKT2	S214	P217L	217	Missense	distal	3	no	21.008	21.123	EPSD	GDSC	19.022	Up-regulation
AGC_Akt_AKT2_ST	O43516	WIPF1	P31751	AKT2	S238	G233S	233	Missense	distal	-5	no	23.282	22.416	EPSD	GDSC;CCLE	19.022	Down-regulation
AGC_Akt_AKT2_ST	O43516	WIPF1	P31751	AKT2	S340	Q336*	336	Missense	distal	-4	no	22.692	23.338	EPSD	GDSC	19.022	Up-regulation
AGC_Akt_AKT2_ST	O43516	WIPF1	P31751	AKT2	S342	Q336*	336	Missense	distal	-6	no	20.655	21.405	EPSD	GDSC	19.022	Up-regulation
AGC_Akt_AKT2_ST	O43516	WIPF1	P31751	AKT2	S376	D371A	371	Missense	distal	-5	no	3.848	23.398	EPSD	GDSC	19.022	Gain
AGC_Akt_AKT2_ST	O43516	WIPF1	P31751	AKT2	S392	N388T	388	Missense	distal	-4	no	20.440	20.592	EPSD	GDSC	19.022	Up-regulation
AGC_Akt_AKT2_ST	O43516	WIPF1	P31751	AKT2	S488	E492G	492	Missense	distal	4	no	24.005	24.021	EPSD	GDSC;CCLE	19.022	Up-regulation
AGC_Akt_AKT2_ST	Q99623	PHB2	P31751	AKT2	S91	G95V	95	Missense	distal	4	no	31.995	32.118	PhosphoSitePlus;EPSD	GDSC;CCLE	19.022	Up-regulation
AGC_Akt_AKT2_ST	Q99623	PHB2	P31751	AKT2	S92	G95V	95	Missense	distal	3	no	21.092	21.024	EPSD	GDSC;CCLE	19.022	Down-regulation
AGC_Akt_AKT2_ST	Q99623	PHB2	P31751	AKT2	S96	G95V	95	Missense	proximal	-1	no	19.548	20.564	EPSD	GDSC;CCLE	19.022	Up-regulation
AGC_Akt_AKT2_ST	Q92945	KHSRP	P31751	AKT2	S144	P140T	140	Missense	distal	-4	no	25.523	25.639	EPSD	GDSC	19.022	Up-regulation
AGC_Akt_AKT2_ST	Q92945	KHSRP	P31751	AKT2	S144	E148*	148	Missense	distal	4	no	25.523	25.850	EPSD	GDSC	19.022	Up-regulation
AGC_Akt_AKT2_ST	Q92945	KHSRP	P31751	AKT2	S193	R190H	190	Missense	distal	-3	no	28.142	8.333	PhosphoSitePlus	GDSC;CCLE	19.022	Loss
AGC_Akt_AKT2_ST	Q92945	KHSRP	P31751	AKT2	S193	E199*	199	Missense	distal	6	no	28.142	26.863	PhosphoSitePlus	GDSC	19.022	Down-regulation
AGC_Akt_AKT2_ST	Q92945	KHSRP	P31751	AKT2	S670	P664L	664	Missense	distal	-6	no	21.412	21.477	EPSD	GDSC;CCLE	19.022	Up-regulation
AGC_Akt_AKT2_ST	Q92945	KHSRP	P31751	AKT2	S670	P664S	664	Missense	distal	-6	no	21.412	20.896	EPSD	GDSC;CCLE	19.022	Down-regulation
AGC_Akt_AKT2_ST	O60331	PIP5K1C	P31751	AKT2	S355	Q362*	362	Missense	distal	7	no	20.070	19.358	EPSD	GDSC	19.022	Down-regulation
AGC_Akt_AKT2_ST	O60331	PIP5K1C	P31751	AKT2	S539	T543M	543	Missense	distal	4	no	21.962	21.985	EPSD	GDSC	19.022	Up-regulation
AGC_Akt_AKT2_ST	O60331	PIP5K1C	P31751	AKT2	S541	T543M	543	Missense	proximal	2	no	25.896	25.817	EPSD	GDSC	19.022	Down-regulation
AGC_Akt_AKT2_ST	O60331	PIP5K1C	P31751	AKT2	T543	T543M	543	Missense	central	0	yes	22.618	0.000	EPSD	GDSC	19.022	Loss
AGC_Akt_AKT2_ST	O60331	PIP5K1C	P31751	AKT2	T543	R550G	550	Missense	distal	7	no	22.618	21.987	EPSD	GDSC	19.022	Down-regulation
AGC_Akt_AKT2_ST	O60331	PIP5K1C	P31751	AKT2	T553	R550G	550	Missense	distal	-3	no	28.809	19.082	EPSD	GDSC	19.022	Down-regulation
AGC_Akt_AKT2_ST	O60331	PIP5K1C	P31751	AKT2	S555	R550G	550	Missense	distal	-5	no	30.031	23.737	PhosphoSitePlus	GDSC	19.022	Down-regulation
AGC_Akt_AKT2_ST	O15111	CHUK	P31751	AKT2	T179	Q174H	174	Missense	distal	-5	no	19.148	11.607	EPSD	GDSC;CCLE	19.022	Loss
AGC_Akt_AKT2_ST	O15111	CHUK	P31751	AKT2	T593	I590T	590	Missense	distal	-3	no	20.968	15.765	EPSD	GDSC;CCLE	19.022	Loss
AGC_Akt_AKT2_ST	P35222	CTNNB1	P31751	AKT2	S129	A135V	135	Missense	distal	6	no	22.753	23.089	EPSD	GDSC;CCLE	19.022	Up-regulation
AGC_Akt_AKT2_ST	P35222	CTNNB1	P31751	AKT2	S552	R549H	549	Missense	distal	-3	no	30.281	10.472	PhosphoSitePlus	GDSC;CCLE	19.022	Loss
AGC_Akt_AKT2_ST	Q7Z6J0	SH3RF1	P31751	AKT2	S125	W126*	126	Missense	proximal	1	no	29.209	28.343	EPSD	GDSC	19.022	Down-regulation
AGC_Akt_AKT2_ST	Q7Z6J0	SH3RF1	P31751	AKT2	S125	V123M	123	Missense	proximal	-2	no	29.209	26.343	EPSD	GDSC;CCLE	19.022	Down-regulation
AGC_Akt_AKT2_ST	Q7Z6J0	SH3RF1	P31751	AKT2	S304	S304F	304	Missense	central	0	yes	27.123	0.000	PhosphoSitePlus	GDSC;CCLE	19.022	Loss
AGC_Akt_AKT2_ST	Q7Z6J0	SH3RF1	P31751	AKT2	S304	R302Q	302	Missense	proximal	-2	no	27.123	24.723	PhosphoSitePlus	GDSC	19.022	Down-regulation
AGC_Akt_AKT2_ST	Q7Z6J0	SH3RF1	P31751	AKT2	S334	P329R	329	Missense	distal	-5	no	18.446	22.543	EPSD	GDSC	19.022	Gain
AGC_Akt_AKT2_ST	Q7Z6J0	SH3RF1	P31751	AKT2	T529	M530T	530	Missense	proximal	1	no	19.448	19.887	EPSD	GDSC;CCLE	19.022	Up-regulation
AGC_Akt_AKT2_ST	Q7Z6J0	SH3RF1	P31751	AKT2	S735	K731R	731	Missense	distal	-4	no	27.962	27.784	EPSD	GDSC	19.022	Down-regulation
AGC_Akt_AKT2_ST	Q7Z6J0	SH3RF1	P31751	AKT2	T782	G779R	779	Missense	distal	-3	no	19.462	29.190	EPSD	GDSC;CCLE	19.022	Up-regulation
AGC_Akt_AKT2_ST	P04406	GAPDH	P31751	AKT2	T19	T19A	19	Missense	central	0	yes	22.837	0.000	EPSD	GDSC;CCLE	19.022	Loss
AGC_Akt_AKT2_ST	P04406	GAPDH	P31751	AKT2	S25	T19A	19	Missense	distal	-6	no	20.612	20.683	EPSD	GDSC;CCLE	19.022	Up-regulation
AGC_Akt_AKT2_ST	P04406	GAPDH	P31751	AKT2	T237	P236S	236	Missense	proximal	-1	no	29.610	29.693	PhosphoSitePlus	GDSC;CCLE	19.022	Up-regulation
CMGC_DYRK_HIPK_HIPK3_ST	Q9UER7	DAXX	Q9H422	HIPK3	S33	A32T	32	Missense	proximal	-1	no	4.350	4.372	EPSD	GDSC;CCLE	1.096	Up-regulation
CMGC_DYRK_HIPK_HIPK3_ST	Q9UER7	DAXX	Q9H422	HIPK3	S178	S176A	176	Missense	proximal	-2	no	4.314	4.294	EPSD	GDSC;CCLE	1.096	Down-regulation
CMGC_DYRK_HIPK_HIPK3_ST	Q9UER7	DAXX	Q9H422	HIPK3	S178	R182H	182	Missense	distal	4	no	4.314	4.295	EPSD	GDSC;CCLE	1.096	Down-regulation
CMGC_DYRK_HIPK_HIPK3_ST	Q9UER7	DAXX	Q9H422	HIPK3	S184	R182H	182	Missense	proximal	-2	no	1.097	1.054	EPSD	GDSC;CCLE	1.096	Loss
CMGC_DYRK_HIPK_HIPK3_ST	Q9UER7	DAXX	Q9H422	HIPK3	S213	S220F	220	Missense	distal	7	no	0.946	1.110	EPSD	GDSC;CCLE	1.096	Gain
CMGC_DYRK_HIPK_HIPK3_ST	Q9UER7	DAXX	Q9H422	HIPK3	S403	R397W	397	Missense	distal	-6	no	1.099	1.066	EPSD	GDSC;CCLE	1.096	Loss
CMGC_DYRK_HIPK_HIPK3_ST	Q9UER7	DAXX	Q9H422	HIPK3	S688	D687V	687	Missense	proximal	-1	no	4.728	4.720	EPSD	GDSC	1.096	Down-regulation
AGC_PKC_PKCa_PRKCB_ST	P10636	MAPT	P05771	PRKCB	S171	D177V	177	Missense	distal	6	no	2.924	2.417	EPSD	GDSC	0.942	Down-regulation
AGC_PKC_PKCa_PRKCB_ST	P10636	MAPT	P05771	PRKCB	S214	V218G	218	Missense	distal	4	no	1.656	1.236	EPSD	GDSC	0.942	Down-regulation
AGC_PKC_PKCa_PRKCB_ST	P10636	MAPT	P05771	PRKCB	S355	E353D	353	Missense	proximal	-2	no	3.476	2.563	EPSD	GDSC;CCLE	0.942	Down-regulation
AGC_PKC_PKCa_PRKCB_ST	P10636	MAPT	P05771	PRKCB	T470	A475V	475	Missense	distal	5	no	3.997	3.862	EPSD	GDSC;CCLE	0.942	Down-regulation
AGC_PKC_PKCa_PRKCB_ST	P10636	MAPT	P05771	PRKCB	S633	V635I	635	Missense	proximal	2	no	1.139	1.159	EPSD	GDSC	0.942	Up-regulation
AGC_PKC_PKCa_PRKCB_ST	P10636	MAPT	P05771	PRKCB	S637	V635I	635	Missense	proximal	-2	no	4.072	4.102	EPSD	GDSC	0.942	Up-regulation
AGC_PKC_PKCa_PRKCB_ST	P05107	ITGB2	P05771	PRKCB	S496	K499N	499	Missense	distal	3	no	3.467	3.321	EPSD	GDSC;CCLE	0.942	Down-regulation
AGC_PKC_PKCa_PRKCB_ST	P28799	GRN	P05771	PRKCB	T18	T18M	18	Missense	central	0	yes	1.080	0.000	EPSD	GDSC;CCLE	0.942	Loss
AGC_PKC_PKCa_PRKCB_ST	P28799	GRN	P05771	PRKCB	T18	F25L	25	Missense	distal	7	no	1.080	1.083	EPSD	GDSC;CCLE	0.942	Up-regulation
AGC_PKC_PKCa_PRKCB_ST	P05771	PRKCB	P05771	PRKCB	S16	S16N	16	Missense	central	0	yes	2.322	0.000	EPSD	GDSC;CCLE	0.942	Loss
AGC_PKC_PKCa_PRKCB_ST	P05771	PRKCB	P05771	PRKCB	T17	S16N	16	Missense	proximal	-1	no	3.564	3.708	EPSD	GDSC;CCLE	0.942	Up-regulation
AGC_PKC_PKCa_PRKCB_ST	P05771	PRKCB	P05771	PRKCB	T48	C50*	50	Missense	proximal	2	no	2.065	-3.587	EPSD	GDSC	0.942	Loss
AGC_PKC_PKCa_PRKCB_ST	P05771	PRKCB	P05771	PRKCB	S241	E243K	243	Missense	proximal	2	no	-3.272	2.142	EPSD	GDSC;CCLE	0.942	Gain
AGC_PKC_PKCa_PRKCB_ST	P05771	PRKCB	P05771	PRKCB	T314	V316A	316	Missense	proximal	2	no	1.587	-1.110	EPSD	GDSC;CCLE	0.942	Loss
AGC_PKC_PKCa_PRKCB_ST	P05771	PRKCB	P05771	PRKCB	T314	E319K	319	Missense	distal	5	no	1.587	1.757	EPSD	GDSC;CCLE	0.942	Up-regulation
AGC_PKC_PKCa_PRKCB_ST	P29353	SHC1	P05771	PRKCB	S17	L13F	13	Missense	distal	-4	no	4.030	3.949	EPSD	GDSC;CCLE	0.942	Down-regulation
AGC_PKC_PKCa_PRKCB_ST	P29353	SHC1	P05771	PRKCB	S17	L18F	18	Missense	proximal	1	no	4.030	4.530	EPSD	GDSC	0.942	Up-regulation
AGC_PKC_PKCa_PRKCB_ST	P29353	SHC1	P05771	PRKCB	S80	G82E	82	Missense	proximal	2	no	0.879	2.576	EPSD	GDSC	0.942	Gain
AGC_PKC_PKCa_PRKCB_ST	P29353	SHC1	P05771	PRKCB	S139	T145P	145	Missense	distal	6	no	3.625	3.839	EPSD;PhosphoSitePlus	GDSC;CCLE	0.942	Up-regulation
AGC_PKC_PKCa_PRKCB_ST	Q03721	KCNC4	P05771	PRKCB	S15	P20S	20	Missense	distal	5	no	1.298	1.355	EPSD;PhosphoSitePlus	GDSC;CCLE	0.942	Up-regulation
AGC_PKC_PKCa_PRKCB_ST	Q03721	KCNC4	P05771	PRKCB	S21	P20S	20	Missense	proximal	-1	no	4.869	4.928	EPSD;PhosphoSitePlus	GDSC;CCLE	0.942	Up-regulation
AGC_PKC_PKCa_PRKCB_ST	Q03721	KCNC4	P05771	PRKCB	S514	S510P	510	Missense	distal	-4	no	3.036	3.132	EPSD	GDSC;CCLE	0.942	Up-regulation
AGC_PKC_PKCa_PRKCB_ST	Q03721	KCNC4	P05771	PRKCB	T578	A573G	573	Missense	distal	-5	no	7.188	7.140	EPSD	GDSC;CCLE	0.942	Down-regulation
AGC_PKC_PKCa_PRKCB_ST	P15336	ATF2	P05771	PRKCB	S340	R342H	342	Missense	proximal	2	no	2.871	-3.490	EPSD	GDSC;CCLE	0.942	Loss
AGC_PKC_PKCa_PRKCB_ST	Q06124	PTPN11	P05771	PRKCB	S580	V583M	583	Missense	distal	3	no	9.230	9.554	EPSD	GDSC;CCLE	0.942	Up-regulation
AGC_PKC_PKCa_PRKCB_ST	P49841	GSK3B	P05771	PRKCB	S2	T8P	8	Missense	distal	6	no	3.927	4.142	EPSD	GDSC	0.942	Up-regulation
AGC_PKC_PKCa_PRKCB_ST	P49841	GSK3B	P05771	PRKCB	S9	T8P	8	Missense	proximal	-1	no	2.332	2.090	PhosphoSitePlus	GDSC	0.942	Down-regulation
AGC_PKC_PKCa_PRKCB_ST	P49841	GSK3B	P05771	PRKCB	S13	T8P	8	Missense	distal	-5	no	1.665	1.589	EPSD	GDSC	0.942	Down-regulation
AGC_PKC_PKCa_PRKCB_ST	Q16625	OCLN	P05771	PRKCB	S166	Y172H	172	Missense	distal	6	no	1.749	2.064	EPSD	GDSC;CCLE	0.942	Up-regulation
AGC_PKC_PKCa_PRKCB_ST	Q16625	OCLN	P05771	PRKCB	S490	K494N	494	Missense	distal	4	no	1.946	1.370	PhosphoSitePlus	GDSC;CCLE	0.942	Down-regulation
AGC_PKC_PKCa_PRKCB_ST	Q9UBS0	RPS6KB2	P05771	PRKCB	T228	G231S	231	Missense	distal	3	no	1.590	1.853	EPSD	GDSC;CCLE	0.942	Up-regulation
AGC_PKC_PKCa_PRKCB_ST	Q9UBS0	RPS6KB2	P05771	PRKCB	S417	R419Q	419	Missense	proximal	2	no	1.767	-4.781	EPSD	GDSC;CCLE	0.942	Loss
AGC_PKC_PKCa_PRKCB_ST	Q9UBS0	RPS6KB2	P05771	PRKCB	S468	R465C	465	Missense	distal	-3	no	3.257	-0.643	EPSD	GDSC;CCLE	0.942	Loss
AGC_PKC_PKCa_PRKCB_ST	Q9UBS0	RPS6KB2	P05771	PRKCB	T470	R465C	465	Missense	distal	-5	no	1.712	1.479	EPSD	GDSC;CCLE	0.942	Down-regulation
AGC_PKC_PKCa_PRKCB_ST	O15519	CFLAR	P05771	PRKCB	S193	D196Y	196	Missense	distal	3	no	3.351	3.230	PhosphoSitePlus	GDSC;CCLE	0.942	Down-regulation
AGC_PKC_PKCa_PRKCB_ST	P48736	PIK3CG	P05771	PRKCB	S227	I220M	220	Missense	distal	-7	no	1.324	1.593	EPSD	GDSC;CCLE	0.942	Up-regulation
AGC_PKC_PKCa_PRKCB_ST	P48736	PIK3CG	P05771	PRKCB	S582	K587Q	587	Missense	distal	5	no	6.675	6.637	PhosphoSitePlus	GDSC;CCLE	0.942	Down-regulation
AGC_PKC_PKCa_PRKCB_ST	P21730	C5AR1	P05771	PRKCB	S332	T339A	339	Missense	distal	7	no	1.111	1.201	EPSD	GDSC;CCLE	0.942	Up-regulation
AGC_PKC_PKCa_PRKCB_ST	P21730	C5AR1	P05771	PRKCB	S332	R337H	337	Missense	distal	5	no	1.111	0.734	EPSD	GDSC;CCLE	0.942	Loss
AGC_PKC_PKCa_PRKCB_ST	P21730	C5AR1	P05771	PRKCB	S334	T339A	339	Missense	distal	5	no	0.990	1.052	PhosphoSitePlus	GDSC;CCLE	0.942	Up-regulation
AGC_PKC_PKCa_PRKCB_ST	P21730	C5AR1	P05771	PRKCB	S334	R337H	337	Missense	distal	3	no	0.990	0.185	PhosphoSitePlus	GDSC;CCLE	0.942	Loss
AGC_PKC_PKCa_PRKCB_ST	P31749	AKT1	P05771	PRKCB	T308	K307N	307	Missense	proximal	-1	no	1.425	1.142	EPSD;PhosphoSitePlus	GDSC;CCLE	0.942	Down-regulation
AGC_PKC_PKCa_PRKCB_ST	Q9P2D0	IBTK	P05771	PRKCB	S695	P702S	702	Missense	distal	7	no	2.838	2.745	EPSD	GDSC;CCLE	0.942	Down-regulation
AGC_PKC_PKCa_PRKCB_ST	Q9P2D0	IBTK	P05771	PRKCB	S1096	T1102N	1102	Missense	distal	6	no	1.943	2.236	EPSD	GDSC;CCLE	0.942	Up-regulation
AGC_PKC_PKCa_PRKCB_ST	Q9P2D0	IBTK	P05771	PRKCB	S1096	P1093R	1093	Missense	distal	-3	no	1.943	5.156	EPSD	GDSC;CCLE	0.942	Up-regulation
AGC_PKC_PKCa_PRKCB_ST	P35568	IRS1	P05771	PRKCB	S24	H26R	26	Missense	proximal	2	no	1.120	7.482	EPSD	GDSC;CCLE	0.942	Up-regulation
AGC_PKC_PKCa_PRKCB_ST	P35568	IRS1	P05771	PRKCB	S268	R267C	267	Missense	proximal	-1	no	3.296	2.593	EPSD	GDSC;CCLE	0.942	Down-regulation
AGC_PKC_PKCa_PRKCB_ST	P35568	IRS1	P05771	PRKCB	S272	R267C	267	Missense	distal	-5	no	1.748	1.515	EPSD	GDSC;CCLE	0.942	Down-regulation
AGC_PKC_PKCa_PRKCB_ST	P35568	IRS1	P05771	PRKCB	S273	R267C	267	Missense	distal	-6	no	1.684	1.330	EPSD	GDSC;CCLE	0.942	Down-regulation
AGC_PKC_PKCa_PRKCB_ST	P35568	IRS1	P05771	PRKCB	S362	R364W	364	Missense	proximal	2	no	4.417	-5.096	EPSD	GDSC	0.942	Loss
AGC_PKC_PKCa_PRKCB_ST	P35568	IRS1	P05771	PRKCB	S362	P368A	368	Missense	distal	6	no	4.417	3.646	EPSD	GDSC;CCLE	0.942	Down-regulation
AGC_PKC_PKCa_PRKCB_ST	P35568	IRS1	P05771	PRKCB	S374	H371R	371	Missense	distal	-3	no	-0.035	2.952	EPSD	GDSC	0.942	Gain
AGC_PKC_PKCa_PRKCB_ST	P35568	IRS1	P05771	PRKCB	S380	A386S	386	Missense	distal	6	no	0.826	1.184	EPSD	GDSC;CCLE	0.942	Gain
AGC_PKC_PKCa_PRKCB_ST	P35568	IRS1	P05771	PRKCB	S413	R411*	411	Missense	proximal	-2	no	1.222	-1.916	EPSD	GDSC	0.942	Loss
AGC_PKC_PKCa_PRKCB_ST	P35568	IRS1	P05771	PRKCB	S603	G597E	597	Missense	distal	-6	no	2.483	2.749	EPSD	GDSC	0.942	Up-regulation
AGC_PKC_PKCa_PRKCB_ST	P35568	IRS1	P05771	PRKCB	S636	A642S	642	Missense	distal	6	no	1.075	1.433	EPSD	GDSC;CCLE	0.942	Up-regulation
AGC_PKC_PKCa_PRKCB_ST	P35568	IRS1	P05771	PRKCB	S1084	S1084R	1084	Missense	central	0	yes	6.007	0.000	EPSD	GDSC	0.942	Loss
AGC_PKC_PKCa_PRKCB_ST	P35568	IRS1	P05771	PRKCB	S1084	A1085D	1085	Missense	proximal	1	no	6.007	5.717	EPSD	GDSC;CCLE	0.942	Down-regulation
AGC_PKC_PKCa_PRKCB_ST	P35568	IRS1	P05771	PRKCB	S1084	R1089G	1089	Missense	distal	5	no	6.007	5.577	EPSD	GDSC;CCLE	0.942	Down-regulation
AGC_PKC_PKCa_PRKCB_ST	P35568	IRS1	P05771	PRKCB	S1101	R1096G	1096	Missense	distal	-5	no	1.721	1.466	EPSD	GDSC;CCLE	0.942	Down-regulation
AGC_PKC_PKCa_PRKCB_ST	P35568	IRS1	P05771	PRKCB	S1218	S1218P	1218	Missense	central	0	yes	2.552	0.000	EPSD	GDSC	0.942	Loss
AGC_PKC_PKCa_PRKCB_ST	P35568	IRS1	P05771	PRKCB	T1219	S1218P	1218	Missense	proximal	-1	no	3.984	3.925	EPSD	GDSC	0.942	Down-regulation
AGC_PKC_PKCa_PRKCB_ST	P11171	EPB41	P05771	PRKCB	S180	E174K	174	Missense	distal	-6	no	1.126	1.271	EPSD	GDSC	0.942	Up-regulation
AGC_PKC_PKCa_PRKCB_ST	P16949	STMN1	P05771	PRKCB	S16	E10K	10	Missense	distal	-6	no	1.083	1.228	EPSD	GDSC;CCLE	0.942	Up-regulation
AGC_PKC_PKCa_PRKCB_ST	P16949	STMN1	P05771	PRKCB	S16	E10*	10	Missense	distal	-6	no	1.083	0.687	EPSD	GDSC	0.942	Loss
AGC_PKC_PKCa_PRKCB_ST	P16949	STMN1	P05771	PRKCB	S31	P36T	36	Missense	distal	5	no	0.894	1.018	EPSD	GDSC;CCLE	0.942	Gain
AGC_PKC_PKCa_PRKCB_ST	P14679	TYR	P05771	PRKCB	S339	G346*	346	Missense	distal	7	no	6.771	6.815	EPSD	GDSC	0.942	Up-regulation
AGC_PKC_PKCa_PRKCB_ST	P14679	TYR	P05771	PRKCB	S339	D333H	333	Missense	distal	-6	no	6.771	6.708	EPSD	GDSC;CCLE	0.942	Down-regulation
AGC_PKC_PKCa_PRKCB_ST	P28329	CHAT	P05771	PRKCB	S244	D250G	250	Missense	distal	6	no	1.015	0.334	EPSD	GDSC;CCLE	0.942	Loss
AGC_PKC_PKCa_PRKCB_ST	P28329	CHAT	P05771	PRKCB	S377	E382K	382	Missense	distal	5	no	1.429	1.599	EPSD	GDSC;CCLE	0.942	Up-regulation
AGC_PKC_PKCa_PRKCB_ST	P28329	CHAT	P05771	PRKCB	T462	S465R	465	Missense	distal	3	no	1.163	1.928	EPSD	GDSC;CCLE	0.942	Up-regulation
AGC_PKC_PKCa_PRKCB_ST	P28329	CHAT	P05771	PRKCB	S464	S465R	465	Missense	proximal	1	no	5.753	7.777	EPSD	GDSC;CCLE	0.942	Up-regulation
AGC_PKC_PKCa_PRKCB_ST	P28329	CHAT	P05771	PRKCB	S465	S465R	465	Missense	central	0	yes	4.475	0.000	EPSD	GDSC;CCLE	0.942	Loss
AGC_PKC_PKCa_PRKCB_ST	P28329	CHAT	P05771	PRKCB	S558	E555D	555	Missense	distal	-3	no	6.129	5.334	EPSD	GDSC;CCLE	0.942	Down-regulation
AGC_PKC_PKCa_PRKCB_ST	P28329	CHAT	P05771	PRKCB	S594	A590D	590	Missense	distal	-4	no	2.132	2.067	EPSD	GDSC;CCLE	0.942	Down-regulation
AGC_PKC_PKCa_PRKCB_ST	Q12906	ILF3	P05771	PRKCB	S382	S384N	384	Missense	proximal	2	no	2.280	2.999	EPSD	GDSC;CCLE	0.942	Up-regulation
AGC_PKC_PKCa_PRKCB_ST	Q12906	ILF3	P05771	PRKCB	S384	S384N	384	Missense	central	0	yes	5.050	0.000	EPSD	GDSC;CCLE	0.942	Loss
AGC_PKC_PKCa_PRKCB_ST	Q12906	ILF3	P05771	PRKCB	S647	R653Q	653	Missense	distal	6	no	10.233	9.428	PhosphoSitePlus	GDSC	0.942	Down-regulation
AGC_PKC_PKCa_PRKCB_ST	P49840	GSK3A	P05771	PRKCB	S266	R272*	272	Missense	distal	6	no	2.948	1.029	EPSD	GDSC	0.942	Down-regulation
CAMK_CAMKL_PASK_PASK_ST	Q96RG2	PASK	Q96RG2	PASK	T512	T512A	512	Missense	central	0	yes	2.316	0.000	EPSD	GDSC	1.643	Loss
CAMK_CAMKL_PASK_PASK_ST	Q96RG2	PASK	Q96RG2	PASK	T512	D508G	508	Missense	distal	-4	no	2.316	2.121	EPSD	GDSC;CCLE	1.643	Down-regulation
CAMK_CAMKL_PASK_PASK_ST	Q96RG2	PASK	Q96RG2	PASK	T850	G845*	845	Missense	distal	-5	no	2.078	2.001	EPSD	GDSC	1.643	Down-regulation
Other_TOPK_PBK_ST	P05412	JUN	Q96KB5	PBK	T297	Q290*	290	Missense	distal	-7	no	2.493	2.422	EPSD	GDSC	2.342	Down-regulation
Other_TOPK_PBK_ST	Q06830	PRDX1	Q96KB5	PBK	S32	I29N	29	Missense	distal	-3	no	5.543	5.470	PhosphoSitePlus	GDSC;CCLE	2.342	Down-regulation
Other_TOPK_PBK_ST	Q06830	PRDX1	Q96KB5	PBK	S106	M100V	100	Missense	distal	-6	no	2.591	2.620	EPSD	GDSC	2.342	Up-regulation
Other_PEK_PEK_EIF2AK3_ST	P05198	EIF2S1	Q9NZJ5	EIF2AK3	S49	R54W	54	Missense	distal	5	no	4.319	3.440	PhosphoSitePlus;EPSD	GDSC;CCLE	0.763	Down-regulation
Other_PEK_PEK_EIF2AK3_ST	P05198	EIF2S1	Q9NZJ5	EIF2AK3	S52	R54W	54	Missense	proximal	2	no	3.905	3.913	EPSD;PhosphoSitePlus	GDSC;CCLE	0.763	Up-regulation
TKL_RAF_RAF_BRAF_ST	P19634	SLC9A1	P15056	BRAF	T653	R647L	647	Missense	distal	-6	no	4.142	3.990	PhosphoSitePlus	GDSC;CCLE	2.269	Down-regulation
TKL_RAF_RAF_BRAF_ST	Q92934	BAD	P15056	BRAF	S134	T137K	137	Missense	distal	3	no	4.161	4.055	EPSD;PhosphoSitePlus	GDSC	2.269	Down-regulation
TKL_RAF_RAF_BRAF_ST	Q92934	BAD	P15056	BRAF	S134	L129F	129	Missense	distal	-5	no	4.161	4.057	EPSD;PhosphoSitePlus	GDSC	2.269	Down-regulation
TKL_RAF_RAF_BRAF_ST	Q92934	BAD	P15056	BRAF	S145	F151L	151	Missense	distal	6	no	2.564	2.536	EPSD	GDSC;CCLE	2.269	Down-regulation
TKL_RAF_RAF_BRAF_ST	P15056	BRAF	P15056	BRAF	T401	A400V	400	Missense	proximal	-1	no	2.275	2.309	EPSD	GDSC;CCLE	2.269	Up-regulation
TKL_RAF_RAF_BRAF_ST	Q05639	EEF1A2	P15056	BRAF	S21	T22I	22	Missense	proximal	1	no	4.317	4.310	PhosphoSitePlus	GDSC;CCLE	2.269	Down-regulation
TKL_RAF_RAF_BRAF_ST	P33981	TTK	P15056	BRAF	S281	P275T	275	Missense	distal	-6	no	4.020	3.791	PhosphoSitePlus;EPSD	GDSC;CCLE	2.269	Down-regulation
TKL_RAF_RAF_BRAF_ST	P33981	TTK	P15056	BRAF	S436	P438S	438	Missense	proximal	2	no	4.309	4.316	EPSD;PhosphoSitePlus	GDSC;CCLE	2.269	Up-regulation
TKL_RAF_RAF_BRAF_ST	P33981	TTK	P15056	BRAF	S742	Q736R	736	Missense	distal	-6	no	2.176	2.525	EPSD	GDSC;CCLE	2.269	Gain
TKL_RAF_RAF_BRAF_ST	P36507	MAP2K2	P15056	BRAF	S222	S222C	222	Missense	central	0	yes	4.451	0.000	EPSD;PhosphoSitePlus	GDSC;CCLE	2.269	Loss
TKL_RAF_RAF_BRAF_ST	P36507	MAP2K2	P15056	BRAF	S226	S222C	222	Missense	distal	-4	no	4.058	4.353	PhosphoSitePlus;EPSD	GDSC;CCLE	2.269	Up-regulation
Other_NEK_NEK9_NEK9_ST	Q8TD19	NEK9	Q8TD19	NEK9	S836	A834V	834	Missense	proximal	-2	no	3.338	3.230	EPSD	GDSC;CCLE	2.671	Down-regulation
Other_NEK_NEK9_NEK9_ST	Q8TD19	NEK9	Q8TD19	NEK9	S869	N873T	873	Missense	distal	4	no	2.774	3.318	EPSD	GDSC	2.671	Up-regulation
CAMK_MLCK_MYLK_ST	O14950	MYL12B	Q15746	MYLK	T19	R14H	14	Missense	distal	-5	no	1.827	1.770	EPSD;PhosphoSitePlus	GDSC;CCLE	1.165	Down-regulation
CAMK_MLCK_MYLK_ST	O14950	MYL12B	Q15746	MYLK	T19	Q16*	16	Missense	distal	-3	no	1.827	1.826	EPSD;PhosphoSitePlus	GDSC	1.165	Down-regulation
CAMK_MLCK_MYLK_ST	O14950	MYL12B	Q15746	MYLK	S20	R14H	14	Missense	distal	-6	no	1.417	1.421	PhosphoSitePlus;EPSD	GDSC;CCLE	1.165	Up-regulation
CAMK_MLCK_MYLK_ST	O14950	MYL12B	Q15746	MYLK	S20	Q16*	16	Missense	distal	-4	no	1.417	1.414	PhosphoSitePlus;EPSD	GDSC	1.165	Down-regulation
CAMK_MLCK_MYLK_ST	O14950	MYL12B	Q15746	MYLK	T160	I157S	157	Missense	distal	-3	no	1.182	1.161	EPSD	GDSC;CCLE	1.165	Loss
AGC_PKC_PKCa_PRKCG_ST	P10636	MAPT	P05129	PRKCG	S341	P340L	340	Missense	proximal	-1	no	119.427	119.921	EPSD	GDSC;CCLE	98.543	Up-regulation
AGC_PKC_PKCa_PRKCG_ST	P10636	MAPT	P05129	PRKCG	S341	G339S	339	Missense	proximal	-2	no	119.427	118.587	EPSD	GDSC;CCLE	98.543	Down-regulation
AGC_PKC_PKCa_PRKCG_ST	P10636	MAPT	P05129	PRKCG	S355	E353D	353	Missense	proximal	-2	no	100.712	101.403	EPSD	GDSC;CCLE	98.543	Up-regulation
AGC_PKC_PKCa_PRKCG_ST	P10636	MAPT	P05129	PRKCG	S641	V635I	635	Missense	distal	-6	no	129.817	128.709	EPSD	GDSC	98.543	Down-regulation
AGC_PKC_PKCa_PRKCG_ST	P98082	DAB2	P05129	PRKCG	S24	K28R	28	Missense	distal	4	no	142.045	141.016	PhosphoSitePlus	GDSC;CCLE	98.543	Down-regulation
AGC_PKC_PKCa_PRKCG_ST	P98082	DAB2	P05129	PRKCG	S249	S249Y	249	Missense	central	0	yes	101.481	0.000	EPSD	GDSC;CCLE	98.543	Loss
AGC_PKC_PKCa_PRKCG_ST	P98082	DAB2	P05129	PRKCG	S327	S328F	328	Missense	proximal	1	no	92.131	102.827	EPSD	GDSC;CCLE	98.543	Gain
AGC_PKC_PKCa_PRKCG_ST	P98082	DAB2	P05129	PRKCG	S436	R441K	441	Missense	distal	5	no	100.881	105.283	EPSD	GDSC;CCLE	98.543	Up-regulation
AGC_PKC_PKCa_PRKCG_ST	P98082	DAB2	P05129	PRKCG	S436	I430V	430	Missense	distal	-6	no	100.881	101.990	EPSD	GDSC	98.543	Up-regulation
AGC_PKC_PKCa_PRKCG_ST	Q03721	KCNC4	P05129	PRKCG	S15	P20S	20	Missense	distal	5	no	135.219	135.688	EPSD;PhosphoSitePlus	GDSC;CCLE	98.543	Up-regulation
AGC_PKC_PKCa_PRKCG_ST	Q03721	KCNC4	P05129	PRKCG	S21	P20S	20	Missense	proximal	-1	no	135.397	140.462	EPSD;PhosphoSitePlus	GDSC;CCLE	98.543	Up-regulation
AGC_PKC_PKCa_PRKCG_ST	Q03721	KCNC4	P05129	PRKCG	T578	A573G	573	Missense	distal	-5	no	118.699	120.026	EPSD	GDSC;CCLE	98.543	Up-regulation
AGC_PKC_PKCa_PRKCG_ST	P43629	KIR3DL1	P05129	PRKCG	S225	G219C	219	Missense	distal	-6	no	104.033	99.973	EPSD	GDSC	98.543	Down-regulation
AGC_PKC_PKCa_PRKCG_ST	P43629	KIR3DL1	P05129	PRKCG	S415	P422S	422	Missense	distal	7	no	129.110	129.143	PhosphoSitePlus	GDSC;CCLE	98.543	Up-regulation
AGC_PKC_PKCa_PRKCG_ST	P49841	GSK3B	P05129	PRKCG	S2	T8P	8	Missense	distal	6	no	103.176	106.989	EPSD	GDSC	98.543	Up-regulation
AGC_PKC_PKCa_PRKCG_ST	P49841	GSK3B	P05129	PRKCG	T7	T8P	8	Missense	proximal	1	no	116.006	110.378	EPSD	GDSC	98.543	Down-regulation
AGC_PKC_PKCa_PRKCG_ST	P49841	GSK3B	P05129	PRKCG	T8	T8P	8	Missense	central	0	yes	103.139	0.000	EPSD	GDSC	98.543	Loss
AGC_PKC_PKCa_PRKCG_ST	P49841	GSK3B	P05129	PRKCG	S9	T8P	8	Missense	proximal	-1	no	131.312	130.131	PhosphoSitePlus	GDSC	98.543	Down-regulation
AGC_PKC_PKCa_PRKCG_ST	P49841	GSK3B	P05129	PRKCG	S13	T8P	8	Missense	distal	-5	no	109.051	111.649	EPSD	GDSC	98.543	Up-regulation
AGC_PKC_PKCa_PRKCG_ST	P49841	GSK3B	P05129	PRKCG	S21	S21L	21	Missense	central	0	yes	118.678	0.000	EPSD	GDSC;CCLE	98.543	Loss
AGC_PKC_PKCa_PRKCG_ST	Q9UBS0	RPS6KB2	P05129	PRKCG	S266	D261E	261	Missense	distal	-5	no	103.558	106.289	EPSD	GDSC;CCLE	98.543	Up-regulation
AGC_PKC_PKCa_PRKCG_ST	Q9UBS0	RPS6KB2	P05129	PRKCG	S266	P268L	268	Missense	proximal	2	no	103.558	107.107	EPSD	GDSC;CCLE	98.543	Up-regulation
AGC_PKC_PKCa_PRKCG_ST	Q9UBS0	RPS6KB2	P05129	PRKCG	S416	R419Q	419	Missense	distal	3	no	98.869	89.675	EPSD	GDSC;CCLE	98.543	Loss
AGC_PKC_PKCa_PRKCG_ST	Q9UBS0	RPS6KB2	P05129	PRKCG	S468	R465C	465	Missense	distal	-3	no	120.352	92.780	EPSD	GDSC;CCLE	98.543	Loss
AGC_PKC_PKCa_PRKCG_ST	Q9UBS0	RPS6KB2	P05129	PRKCG	T470	R465C	465	Missense	distal	-5	no	97.013	103.681	EPSD	GDSC;CCLE	98.543	Gain
AGC_PKC_PKCa_PRKCG_ST	Q14155	ARHGEF7	P05129	PRKCG	S761	R758C	758	Missense	distal	-3	no	124.385	96.812	EPSD;PhosphoSitePlus	GDSC;CCLE	98.543	Loss
AGC_PKC_PKCa_PRKCG_ST	P21730	C5AR1	P05129	PRKCG	S314	L315H	315	Missense	proximal	1	no	108.132	104.504	EPSD	GDSC;CCLE	98.543	Down-regulation
AGC_PKC_PKCa_PRKCG_ST	P21730	C5AR1	P05129	PRKCG	S317	L315H	315	Missense	proximal	-2	no	98.724	102.474	EPSD	GDSC;CCLE	98.543	Up-regulation
AGC_PKC_PKCa_PRKCG_ST	P21730	C5AR1	P05129	PRKCG	S334	T339A	339	Missense	distal	5	no	102.791	101.215	PhosphoSitePlus	GDSC;CCLE	98.543	Down-regulation
AGC_PKC_PKCa_PRKCG_ST	P21730	C5AR1	P05129	PRKCG	S334	R337H	337	Missense	distal	3	no	102.791	102.442	PhosphoSitePlus	GDSC;CCLE	98.543	Down-regulation
AGC_PKC_PKCa_PRKCG_ST	P06127	CD5	P05129	PRKCG	T434	V437I	437	Missense	distal	3	no	123.839	121.908	PhosphoSitePlus;EPSD	GDSC;CCLE	98.543	Down-regulation
AGC_PKC_PKCa_PRKCG_ST	P06127	CD5	P05129	PRKCG	T436	V437I	437	Missense	proximal	1	no	119.055	123.240	EPSD;PhosphoSitePlus	GDSC;CCLE	98.543	Up-regulation
AGC_PKC_PKCa_PRKCG_ST	P28329	CHAT	P05129	PRKCG	S244	D250G	250	Missense	distal	6	no	119.660	122.570	EPSD	GDSC;CCLE	98.543	Up-regulation
AGC_PKC_PKCa_PRKCG_ST	P28329	CHAT	P05129	PRKCG	S464	S465R	465	Missense	proximal	1	no	131.934	140.871	EPSD	GDSC;CCLE	98.543	Up-regulation
AGC_PKC_PKCa_PRKCG_ST	P28329	CHAT	P05129	PRKCG	S465	S465R	465	Missense	central	0	yes	123.224	0.000	EPSD	GDSC;CCLE	98.543	Loss
AGC_PKC_PKCa_PRKCG_ST	P28329	CHAT	P05129	PRKCG	S558	E555D	555	Missense	distal	-3	no	134.661	130.501	EPSD	GDSC;CCLE	98.543	Down-regulation
AGC_PKC_PKCa_PRKCG_ST	P28329	CHAT	P05129	PRKCG	S594	A590D	590	Missense	distal	-4	no	127.395	128.117	EPSD	GDSC;CCLE	98.543	Up-regulation
AGC_PKC_PKCa_PRKCG_ST	P08138	NGFR	P05129	PRKCG	S287	N286S	286	Missense	proximal	-1	no	98.199	101.851	EPSD	GDSC;CCLE	98.543	Gain
TK_PDGFR_FLT3_Y	P36888	FLT3	P36888	FLT3	Y793	D787H	787	Missense	distal	-6	no	0.779	0.658	EPSD	GDSC;CCLE	0.779	Loss
TK_PDGFR_FLT3_Y	P36888	FLT3	P36888	FLT3	Y955	A948T	948	Missense	distal	-7	no	1.584	1.573	PhosphoSitePlus;EPSD	GDSC;CCLE	0.779	Down-regulation
TK_PDGFR_FLT3_Y	Q15118	PDK1	P36888	FLT3	Y243	I245S	245	Missense	proximal	2	no	1.394	1.384	PhosphoSitePlus	GDSC	0.779	Down-regulation
CMGC_SRPK_SRPK1_ST	Q96SB4	SRPK1	Q96SB4	SRPK1	S249	G242V	242	Missense	distal	-7	no	57.729	54.402	EPSD	GDSC;CCLE	48.822	Down-regulation
CMGC_SRPK_SRPK1_ST	Q96SB4	SRPK1	Q96SB4	SRPK1	S249	G242R	242	Missense	distal	-7	no	57.729	74.590	EPSD	GDSC;CCLE	48.822	Up-regulation
CMGC_SRPK_SRPK1_ST	Q96SB4	SRPK1	Q96SB4	SRPK1	S309	E314D	314	Missense	distal	5	no	75.655	71.221	PhosphoSitePlus;EPSD	GDSC	48.822	Down-regulation
CMGC_SRPK_SRPK1_ST	Q96SB4	SRPK1	Q96SB4	SRPK1	S311	K318T	318	Missense	distal	7	no	74.113	72.652	EPSD	GDSC	48.822	Down-regulation
CMGC_SRPK_SRPK1_ST	Q96SB4	SRPK1	Q96SB4	SRPK1	S311	E314D	314	Missense	distal	3	no	74.113	69.983	EPSD	GDSC	48.822	Down-regulation
CMGC_SRPK_SRPK1_ST	Q07955	SRSF1	Q96SB4	SRPK1	S116	N121T	121	Missense	distal	5	no	76.136	71.319	EPSD	GDSC;CCLE	48.822	Down-regulation
CMGC_SRPK_SRPK1_ST	Q07955	SRSF1	Q96SB4	SRPK1	S119	V125G	125	Missense	distal	6	no	68.718	72.459	EPSD	GDSC;CCLE	48.822	Up-regulation
CMGC_SRPK_SRPK1_ST	Q07955	SRSF1	Q96SB4	SRPK1	S119	N121T	121	Missense	proximal	2	no	68.718	67.065	EPSD	GDSC;CCLE	48.822	Down-regulation
CMGC_SRPK_SRPK1_ST	Q07955	SRSF1	Q96SB4	SRPK1	S131	V125G	125	Missense	distal	-6	no	50.381	52.472	EPSD	GDSC;CCLE	48.822	Up-regulation
CMGC_SRPK_SRPK1_ST	Q9BWF3	RBM4	Q96SB4	SRPK1	S309	Y303H	303	Missense	distal	-6	no	96.030	96.239	PhosphoSitePlus	GDSC	48.822	Up-regulation
CMGC_SRPK_SRPK1_ST	Q9BWF3	RBM4	Q96SB4	SRPK1	T315	P319L	319	Missense	distal	4	no	79.940	77.363	EPSD	GDSC;CCLE	48.822	Down-regulation
AGC_PKC_PKCi_PRKCZ_ST	Q9Y6Q9	NCOA3	Q05513	PRKCZ	S101	Q96R	96	Missense	distal	-5	no	44.264	41.854	EPSD	GDSC;CCLE	31.494	Down-regulation
AGC_PKC_PKCi_PRKCZ_ST	Q9Y6Q9	NCOA3	Q05513	PRKCZ	T1059	T1059N	1059	Missense	central	0	yes	33.442	0.000	PhosphoSitePlus;EPSD	GDSC;CCLE	31.494	Loss
AGC_PKC_PKCi_PRKCZ_ST	Q9Y6Q9	NCOA3	Q05513	PRKCZ	T1059	T1059A	1059	Missense	central	0	yes	33.442	0.000	PhosphoSitePlus;EPSD	GDSC;CCLE	31.494	Loss
AGC_PKC_PKCi_PRKCZ_ST	Q9Y6Q9	NCOA3	Q05513	PRKCZ	S1062	T1059N	1059	Missense	distal	-3	no	41.445	40.122	EPSD;PhosphoSitePlus	GDSC;CCLE	31.494	Down-regulation
AGC_PKC_PKCi_PRKCZ_ST	Q9Y6Q9	NCOA3	Q05513	PRKCZ	S1062	T1059A	1059	Missense	distal	-3	no	41.445	36.825	EPSD;PhosphoSitePlus	GDSC;CCLE	31.494	Down-regulation
AGC_PKC_PKCi_PRKCZ_ST	Q16625	OCLN	Q05513	PRKCZ	S302	V308L	308	Missense	distal	6	no	34.086	34.663	EPSD	GDSC	31.494	Up-regulation
AGC_PKC_PKCi_PRKCZ_ST	Q16625	OCLN	Q05513	PRKCZ	T403	D401N	401	Missense	proximal	-2	no	36.867	30.789	EPSD;PhosphoSitePlus	GDSC;CCLE	31.494	Loss
AGC_PKC_PKCi_PRKCZ_ST	Q16625	OCLN	Q05513	PRKCZ	T403	Y402C	402	Missense	proximal	-1	no	36.867	36.832	EPSD;PhosphoSitePlus	GDSC;CCLE	31.494	Down-regulation
AGC_PKC_PKCi_PRKCZ_ST	Q16625	OCLN	Q05513	PRKCZ	S490	K494N	494	Missense	distal	4	no	31.984	33.704	EPSD	GDSC;CCLE	31.494	Up-regulation
AGC_PKC_PKCi_PRKCZ_ST	P10636	MAPT	Q05513	PRKCZ	T52	Q49H	49	Missense	distal	-3	no	30.196	33.655	EPSD	GDSC	31.494	Gain
AGC_PKC_PKCi_PRKCZ_ST	P10636	MAPT	Q05513	PRKCZ	S171	D177V	177	Missense	distal	6	no	39.858	36.547	EPSD	GDSC	31.494	Down-regulation
AGC_PKC_PKCi_PRKCZ_ST	P10636	MAPT	Q05513	PRKCZ	S341	P340L	340	Missense	proximal	-1	no	32.156	32.316	EPSD	GDSC;CCLE	31.494	Up-regulation
AGC_PKC_PKCi_PRKCZ_ST	P10636	MAPT	Q05513	PRKCZ	S341	G339S	339	Missense	proximal	-2	no	32.156	30.759	EPSD	GDSC;CCLE	31.494	Loss
AGC_PKC_PKCi_PRKCZ_ST	P10636	MAPT	Q05513	PRKCZ	S633	V635I	635	Missense	proximal	2	no	31.601	26.640	EPSD	GDSC	31.494	Loss
AGC_PKC_PKCi_PRKCZ_ST	P10636	MAPT	Q05513	PRKCZ	T744	S739C	739	Missense	distal	-5	no	31.521	33.068	EPSD	GDSC	31.494	Up-regulation
AGC_PKC_PKCi_PRKCZ_ST	P61587	RND3	Q05513	PRKCZ	T231	A228T	228	Missense	distal	-3	no	29.237	33.857	EPSD	GDSC;CCLE	31.494	Gain
AGC_PKC_PKCi_PRKCZ_ST	P61587	RND3	Q05513	PRKCZ	S240	K235T	235	Missense	distal	-5	no	36.968	37.078	EPSD	GDSC;CCLE	31.494	Up-regulation
AGC_PKC_PKCi_PRKCZ_ST	P61587	RND3	Q05513	PRKCZ	S240	T242A	242	Missense	proximal	2	no	36.968	38.579	EPSD	GDSC;CCLE	31.494	Up-regulation
AGC_PKC_PKCi_PRKCZ_ST	O43175	PHGDH	Q05513	PRKCZ	T57	A56T	56	Missense	proximal	-1	no	36.729	35.781	EPSD;PhosphoSitePlus	GDSC;CCLE	31.494	Down-regulation
AGC_PKC_PKCi_PRKCZ_ST	P53004	BLVRA	Q05513	PRKCZ	S21	R18G	18	Missense	distal	-3	no	38.923	24.685	EPSD	GDSC	31.494	Loss
AGC_PKC_PKCi_PRKCZ_ST	Q13118	KLF10	Q05513	PRKCZ	S184	R188S	188	Missense	distal	4	no	36.025	34.799	EPSD	GDSC	31.494	Down-regulation
AGC_PKC_PKCi_PRKCZ_ST	Q13118	KLF10	Q05513	PRKCZ	S384	T390M	390	Missense	distal	6	no	39.136	40.900	PhosphoSitePlus;EPSD	GDSC	31.494	Up-regulation
AGC_PKC_PKCi_PRKCZ_ST	Q13118	KLF10	Q05513	PRKCZ	T394	T390M	390	Missense	distal	-4	no	34.257	34.223	EPSD	GDSC	31.494	Down-regulation
AGC_PKC_PKCi_PRKCZ_ST	Q13118	KLF10	Q05513	PRKCZ	T422	F429C	429	Missense	distal	7	no	33.343	35.353	EPSD	GDSC;CCLE	31.494	Up-regulation
AGC_PKC_PKCi_PRKCZ_ST	Q13118	KLF10	Q05513	PRKCZ	T424	F429C	429	Missense	distal	5	no	38.059	38.117	EPSD	GDSC;CCLE	31.494	Up-regulation
AGC_PKC_PKCi_PRKCZ_ST	P49841	GSK3B	Q05513	PRKCZ	S9	T8P	8	Missense	proximal	-1	no	36.187	35.586	EPSD;PhosphoSitePlus	GDSC	31.494	Down-regulation
AGC_PKC_PKCi_PRKCZ_ST	P49757	NUMB	Q05513	PRKCZ	S7	R10K	10	Missense	distal	3	no	59.036	58.307	PhosphoSitePlus;EPSD	GDSC;CCLE	31.494	Down-regulation
AGC_PKC_PKCi_PRKCZ_ST	P49757	NUMB	Q05513	PRKCZ	S276	F280L	280	Missense	distal	4	no	32.914	34.308	EPSD	GDSC;CCLE	31.494	Up-regulation
AGC_PKC_PKCi_PRKCZ_ST	Q15831	STK11	Q05513	PRKCZ	S307	R310P	310	Missense	distal	3	no	48.975	32.908	EPSD;PhosphoSitePlus	GDSC;CCLE	31.494	Down-regulation
AGC_PKC_PKCi_PRKCZ_ST	Q15831	STK11	Q05513	PRKCZ	T336	W332*	332	Missense	distal	-4	no	42.436	42.236	EPSD	GDSC	31.494	Down-regulation
AGC_PKC_PKCi_PRKCZ_ST	O43315	AQP9	Q05513	PRKCZ	S11	K13E	13	Missense	proximal	2	no	36.903	27.296	EPSD;PhosphoSitePlus	GDSC;CCLE	31.494	Loss
AGC_PKC_PKCi_PRKCZ_ST	O43315	AQP9	Q05513	PRKCZ	S20	K13E	13	Missense	distal	-7	no	32.078	26.258	EPSD	GDSC;CCLE	31.494	Loss
AGC_PKC_PKCi_PRKCZ_ST	O43315	AQP9	Q05513	PRKCZ	S20	T26I	26	Missense	distal	6	no	32.078	32.433	EPSD	GDSC;CCLE	31.494	Up-regulation
AGC_PKC_PKCi_PRKCZ_ST	O43315	AQP9	Q05513	PRKCZ	S20	T26S	26	Missense	distal	6	no	32.078	33.459	EPSD	GDSC;CCLE	31.494	Up-regulation
AGC_PKC_PKCi_PRKCZ_ST	O43315	AQP9	Q05513	PRKCZ	S21	T26I	26	Missense	distal	5	no	44.259	44.473	EPSD	GDSC;CCLE	31.494	Up-regulation
AGC_PKC_PKCi_PRKCZ_ST	O43315	AQP9	Q05513	PRKCZ	S21	T26S	26	Missense	distal	5	no	44.259	44.250	EPSD	GDSC;CCLE	31.494	Down-regulation
AGC_PKC_PKCi_PRKCZ_ST	P35580	MYH10	Q05513	PRKCZ	S561	G558R	558	Missense	distal	-3	no	22.882	37.120	EPSD	GDSC;CCLE	31.494	Gain
AGC_PKC_PKCi_PRKCZ_ST	P35580	MYH10	Q05513	PRKCZ	S1129	D1126Y	1126	Missense	distal	-3	no	31.736	30.862	EPSD	GDSC;CCLE	31.494	Loss
AGC_PKC_PKCi_PRKCZ_ST	P35580	MYH10	Q05513	PRKCZ	S1487	K1481T	1481	Missense	distal	-6	no	34.944	35.096	EPSD	GDSC;CCLE	31.494	Up-regulation
AGC_PKC_PKCi_PRKCZ_ST	Q9UBS0	RPS6KB2	Q05513	PRKCZ	S377	A375S	375	Missense	proximal	-2	no	33.520	31.490	EPSD	GDSC;CCLE	31.494	Loss
AGC_PKC_PKCi_PRKCZ_ST	Q9UBS0	RPS6KB2	Q05513	PRKCZ	S377	D372H	372	Missense	distal	-5	no	33.520	32.821	EPSD	GDSC;CCLE	31.494	Down-regulation
AGC_PKC_PKCi_PRKCZ_ST	Q9UBS0	RPS6KB2	Q05513	PRKCZ	S416	R419Q	419	Missense	distal	3	no	48.455	42.858	EPSD	GDSC;CCLE	31.494	Down-regulation
AGC_PKC_PKCi_PRKCZ_ST	Q9UBS0	RPS6KB2	Q05513	PRKCZ	S468	R465C	465	Missense	distal	-3	no	51.854	31.820	EPSD	GDSC;CCLE	31.494	Down-regulation
AGC_PKC_PKCi_PRKCZ_ST	Q9UBS0	RPS6KB2	Q05513	PRKCZ	T470	R465C	465	Missense	distal	-5	no	29.648	33.233	EPSD	GDSC;CCLE	31.494	Gain
AGC_PKC_PKCi_PRKCZ_ST	P08047	SP1	Q05513	PRKCZ	S73	A66G	66	Missense	distal	-7	no	40.983	38.533	EPSD	GDSC;CCLE	31.494	Down-regulation
AGC_PKC_PKCi_PRKCZ_ST	P08047	SP1	Q05513	PRKCZ	T651	G652D	652	Missense	proximal	1	no	36.603	36.200	EPSD	GDSC;CCLE	31.494	Down-regulation
AGC_PKC_PKCi_PRKCZ_ST	P08047	SP1	Q05513	PRKCZ	T668	R669H	669	Missense	proximal	1	no	40.198	39.023	PhosphoSitePlus;EPSD	GDSC;CCLE	31.494	Down-regulation
AGC_PKC_PKCi_PRKCZ_ST	P27448	MARK3	Q05513	PRKCZ	T297	R295H	295	Missense	proximal	-2	no	45.866	37.014	EPSD	GDSC;CCLE	31.494	Down-regulation
AGC_PKC_PKCi_PRKCZ_ST	P27448	MARK3	Q05513	PRKCZ	S390	R388T	388	Missense	proximal	-2	no	32.699	21.469	EPSD	GDSC;CCLE	31.494	Loss
AGC_PKC_PKCi_PRKCZ_ST	P27448	MARK3	Q05513	PRKCZ	S390	S396I	396	Missense	distal	6	no	32.699	31.674	EPSD	GDSC;CCLE	31.494	Down-regulation
AGC_PKC_PKCi_PRKCZ_ST	P27448	MARK3	Q05513	PRKCZ	T507	R505*	505	Missense	proximal	-2	no	37.529	15.224	EPSD	GDSC	31.494	Loss
AGC_PKC_PKCi_PRKCZ_ST	P27448	MARK3	Q05513	PRKCZ	T515	A516T	516	Missense	proximal	1	no	32.521	31.912	EPSD	GDSC;CCLE	31.494	Down-regulation
AGC_PKC_PKCi_PRKCZ_ST	P27448	MARK3	Q05513	PRKCZ	S618	I622M	622	Missense	distal	4	no	32.789	36.883	EPSD	GDSC;CCLE	31.494	Up-regulation
AGC_PKC_PKCi_PRKCZ_ST	P27448	MARK3	Q05513	PRKCZ	S643	S643F	643	Missense	central	0	yes	36.166	0.000	EPSD	GDSC;CCLE	31.494	Loss
AGC_PKC_PKCi_PRKCZ_ST	P27448	MARK3	Q05513	PRKCZ	S734	A739G	739	Missense	distal	5	no	44.141	44.007	EPSD	GDSC;CCLE	31.494	Down-regulation
AGC_PKC_PKCi_PRKCZ_ST	P35568	IRS1	Q05513	PRKCZ	S24	H26R	26	Missense	proximal	2	no	37.310	41.464	EPSD	GDSC;CCLE	31.494	Up-regulation
AGC_PKC_PKCi_PRKCZ_ST	P35568	IRS1	Q05513	PRKCZ	S268	R267C	267	Missense	proximal	-1	no	36.016	34.078	EPSD	GDSC;CCLE	31.494	Down-regulation
AGC_PKC_PKCi_PRKCZ_ST	P35568	IRS1	Q05513	PRKCZ	S362	R364W	364	Missense	proximal	2	no	36.695	22.358	EPSD	GDSC	31.494	Loss
AGC_PKC_PKCi_PRKCZ_ST	P35568	IRS1	Q05513	PRKCZ	S362	P368A	368	Missense	distal	6	no	36.695	39.971	EPSD	GDSC;CCLE	31.494	Up-regulation
AGC_PKC_PKCi_PRKCZ_ST	P35568	IRS1	Q05513	PRKCZ	S413	R411*	411	Missense	proximal	-2	no	47.563	25.258	EPSD	GDSC	31.494	Loss
AGC_PKC_PKCi_PRKCZ_ST	P35568	IRS1	Q05513	PRKCZ	T851	R854C	854	Missense	distal	3	no	31.817	16.757	EPSD	GDSC	31.494	Loss
AGC_PKC_PKCi_PRKCZ_ST	P35568	IRS1	Q05513	PRKCZ	S1100	R1096G	1096	Missense	distal	-4	no	34.706	34.946	EPSD	GDSC;CCLE	31.494	Up-regulation
AGC_PKC_PKCi_PRKCZ_ST	P35568	IRS1	Q05513	PRKCZ	S1101	R1096G	1096	Missense	distal	-5	no	30.885	33.000	EPSD	GDSC;CCLE	31.494	Gain
AGC_PKC_PKCi_PRKCZ_ST	P35568	IRS1	Q05513	PRKCZ	S1218	S1218P	1218	Missense	central	0	yes	40.982	0.000	EPSD	GDSC	31.494	Loss
AGC_PKC_PKCi_PRKCZ_ST	P35568	IRS1	Q05513	PRKCZ	T1219	S1218P	1218	Missense	proximal	-1	no	41.313	40.457	EPSD	GDSC	31.494	Down-regulation
AGC_PKC_PKCi_PRKCZ_ST	P35568	IRS1	Q05513	PRKCZ	S1222	S1218P	1218	Missense	distal	-4	no	41.403	41.801	EPSD	GDSC	31.494	Up-regulation
AGC_PKC_PKCi_PRKCZ_ST	P35568	IRS1	Q05513	PRKCZ	S1223	S1218P	1218	Missense	distal	-5	no	49.574	50.966	EPSD	GDSC	31.494	Up-regulation
AGC_PKC_PKCi_PRKCZ_ST	P35568	IRS1	Q05513	PRKCZ	S1227	S1233N	1233	Missense	distal	6	no	44.292	44.923	EPSD	GDSC;CCLE	31.494	Up-regulation
AGC_PKC_PKCi_PRKCZ_ST	Q8N2W9	PIAS4	Q05513	PRKCZ	S18	L24R	24	Missense	distal	6	no	41.522	45.716	PhosphoSitePlus	GDSC;CCLE	31.494	Up-regulation
AGC_PKC_PKCi_PRKCZ_ST	Q8N2W9	PIAS4	Q05513	PRKCZ	S18	D19N	19	Missense	proximal	1	no	41.522	41.724	PhosphoSitePlus	GDSC;CCLE	31.494	Up-regulation
AGC_PKC_PKCi_PRKCZ_ST	Q8N2W9	PIAS4	Q05513	PRKCZ	S18	R16*	16	Missense	proximal	-2	no	41.522	19.218	PhosphoSitePlus	GDSC	31.494	Loss
AGC_PKC_PKCi_PRKCZ_ST	Q8N2W9	PIAS4	Q05513	PRKCZ	S416	R413H	413	Missense	distal	-3	no	37.456	29.027	EPSD	GDSC	31.494	Loss
AGC_PKC_PKCi_PRKCZ_ST	P35222	CTNNB1	Q05513	PRKCZ	T547	R549H	549	Missense	proximal	2	no	41.763	37.610	EPSD	GDSC;CCLE	31.494	Down-regulation
AGC_PKC_PKCi_PRKCZ_ST	P35222	CTNNB1	Q05513	PRKCZ	S552	R549H	549	Missense	distal	-3	no	34.285	25.856	EPSD	GDSC;CCLE	31.494	Loss
AGC_PKC_PKCi_PRKCZ_ST	P35612	ADD2	Q05513	PRKCZ	S472	S472R	472	Missense	central	0	yes	40.395	0.000	EPSD	GDSC;CCLE	31.494	Loss
AGC_PKC_PKCi_PRKCZ_ST	P35612	ADD2	Q05513	PRKCZ	S472	E467D	467	Missense	distal	-5	no	40.395	39.858	EPSD	GDSC;CCLE	31.494	Down-regulation
AGC_PKC_PKCi_PRKCZ_ST	P35612	ADD2	Q05513	PRKCZ	T545	E543K	543	Missense	proximal	-2	no	27.429	37.323	EPSD	GDSC	31.494	Gain
AGC_PKC_PKCi_PRKCZ_ST	P35612	ADD2	Q05513	PRKCZ	S703	R710Q	710	Missense	distal	7	no	32.105	30.807	EPSD	GDSC;CCLE	31.494	Loss
AGC_PKC_PKCi_PRKCZ_ST	P35612	ADD2	Q05513	PRKCZ	S713	R710Q	710	Missense	distal	-3	no	51.158	39.271	PhosphoSitePlus	GDSC;CCLE	31.494	Down-regulation
AGC_PKC_PKCi_PRKCZ_ST	P35612	ADD2	Q05513	PRKCZ	S718	V724M	724	Missense	distal	6	no	50.333	51.074	EPSD	GDSC;CCLE	31.494	Up-regulation
AGC_PKC_PKCi_PRKCZ_ST	P35611	ADD1	Q05513	PRKCZ	S358	T364A	364	Missense	distal	6	no	33.099	36.043	EPSD	GDSC;CCLE	31.494	Up-regulation
AGC_PKC_PKCi_PRKCZ_ST	P35611	ADD1	Q05513	PRKCZ	S481	H478Y	478	Missense	distal	-3	no	37.015	36.095	EPSD	GDSC	31.494	Down-regulation
AGC_PKC_PKCi_PRKCZ_ST	Q9UJZ1	STOML2	Q05513	PRKCZ	S29	R34*	34	Missense	distal	5	no	32.184	31.339	EPSD	GDSC	31.494	Loss
AGC_PKC_PKCi_PRKCZ_ST	Q9UJZ1	STOML2	Q05513	PRKCZ	S29	R34Q	34	Missense	distal	5	no	32.184	31.556	EPSD	GDSC	31.494	Down-regulation
AGC_PKC_PKCi_PRKCZ_ST	P55211	CASP9	Q05513	PRKCZ	S144	G147E	147	Missense	distal	3	no	47.095	40.446	PhosphoSitePlus	GDSC;CCLE	31.494	Down-regulation
AGC_PKC_PKCi_PRKCZ_ST	P55211	CASP9	Q05513	PRKCZ	S175	G176R	176	Missense	proximal	1	no	31.358	33.072	EPSD	GDSC;CCLE	31.494	Gain
AGC_PKC_PKCi_PRKCZ_ST	P78563	ADARB1	Q05513	PRKCZ	S13	S10T	10	Missense	distal	-3	no	30.304	32.159	EPSD	GDSC	31.494	Gain
AGC_PKC_PKCi_PRKCZ_ST	P78563	ADARB1	Q05513	PRKCZ	S26	N24S	24	Missense	proximal	-2	no	33.331	34.031	EPSD	GDSC;CCLE	31.494	Up-regulation
AGC_PKC_PKCi_PRKCZ_ST	P78563	ADARB1	Q05513	PRKCZ	S31	N24S	24	Missense	distal	-7	no	32.318	32.518	EPSD	GDSC;CCLE	31.494	Up-regulation
AGC_PKC_PKCi_PRKCZ_ST	Q9UIQ6	LNPEP	Q05513	PRKCZ	S666	V659A	659	Missense	distal	-7	no	43.902	47.845	EPSD	GDSC;CCLE	31.494	Up-regulation
AGC_PKC_PKCi_PRKCZ_ST	Q15466	NR0B2	Q05513	PRKCZ	T55	C50Y	50	Missense	distal	-5	no	32.103	31.000	PhosphoSitePlus	GDSC	31.494	Loss
AGC_PKC_PKCi_PRKCZ_ST	P28329	CHAT	Q05513	PRKCZ	S125	E128*	128	Missense	distal	3	no	38.571	28.901	EPSD	GDSC	31.494	Loss
AGC_PKC_PKCi_PRKCZ_ST	P28329	CHAT	Q05513	PRKCZ	S377	E382K	382	Missense	distal	5	no	38.172	38.434	EPSD	GDSC;CCLE	31.494	Up-regulation
AGC_PKC_PKCi_PRKCZ_ST	P28329	CHAT	Q05513	PRKCZ	T462	S465R	465	Missense	distal	3	no	26.594	36.092	EPSD	GDSC;CCLE	31.494	Gain
AGC_PKC_PKCi_PRKCZ_ST	P28329	CHAT	Q05513	PRKCZ	S464	S465R	465	Missense	proximal	1	no	31.482	33.920	EPSD	GDSC;CCLE	31.494	Gain
AGC_PKC_PKCi_PRKCZ_ST	P28329	CHAT	Q05513	PRKCZ	S465	S465R	465	Missense	central	0	yes	35.215	0.000	EPSD	GDSC;CCLE	31.494	Loss
AGC_PKC_PKCi_PRKCZ_ST	P28329	CHAT	Q05513	PRKCZ	S558	E555D	555	Missense	distal	-3	no	30.107	40.066	EPSD	GDSC;CCLE	31.494	Gain
AGC_PKC_PKCi_PRKCZ_ST	P46937	YAP1	Q05513	PRKCZ	S105	P98L	98	Missense	distal	-7	no	34.124	36.359	EPSD	GDSC;CCLE	31.494	Up-regulation
AGC_PKC_PKCi_PRKCZ_ST	P46937	YAP1	Q05513	PRKCZ	S499	S499G	499	Missense	central	0	yes	38.495	0.000	EPSD	GDSC;CCLE	31.494	Loss
AGC_PKC_PKCi_PRKCZ_ST	Q5JVS0	HABP4	Q05513	PRKCZ	T375	R376Q	376	Missense	proximal	1	no	43.427	41.153	PhosphoSitePlus;EPSD	GDSC;CCLE	31.494	Down-regulation
AGC_PKC_PKCi_PRKCZ_ST	Q8IX03	WWC1	Q05513	PRKCZ	T923	L919F	919	Missense	distal	-4	no	31.551	31.402	EPSD	GDSC;CCLE	31.494	Loss
AGC_PKC_PKCi_PRKCZ_ST	Q8IX03	WWC1	Q05513	PRKCZ	T923	R920Q	920	Missense	distal	-3	no	31.551	19.664	EPSD	GDSC;CCLE	31.494	Loss
AGC_PKC_PKCi_PRKCZ_ST	Q8IX03	WWC1	Q05513	PRKCZ	S947	R941Q	941	Missense	distal	-6	no	32.425	32.824	EPSD	GDSC	31.494	Up-regulation
AGC_PKC_PKCi_PRKCZ_ST	Q8IX03	WWC1	Q05513	PRKCZ	S974	R972W	972	Missense	proximal	-2	no	37.061	18.887	EPSD	GDSC;CCLE	31.494	Loss
AGC_PKC_PKCi_PRKCZ_ST	Q8IX03	WWC1	Q05513	PRKCZ	S978	R972W	972	Missense	distal	-6	no	37.486	38.161	PhosphoSitePlus;EPSD	GDSC;CCLE	31.494	Up-regulation
AGC_PKC_PKCi_PRKCZ_ST	Q8IX03	WWC1	Q05513	PRKCZ	S978	I985V	985	Missense	distal	7	no	37.486	34.835	PhosphoSitePlus;EPSD	GDSC;CCLE	31.494	Down-regulation
AGC_PKC_PKCi_PRKCZ_ST	P55040	GEM	Q05513	PRKCZ	T12	G14S	14	Missense	proximal	2	no	39.531	38.663	EPSD	GDSC;CCLE	31.494	Down-regulation
AGC_PKC_PKCi_PRKCZ_ST	P55040	GEM	Q05513	PRKCZ	S261	R258M	258	Missense	distal	-3	no	45.568	34.580	PhosphoSitePlus	GDSC	31.494	Down-regulation
AGC_PKC_PKCi_PRKCZ_ST	P55040	GEM	Q05513	PRKCZ	S287	M281I	281	Missense	distal	-6	no	32.483	32.754	EPSD	GDSC;CCLE	31.494	Up-regulation
AGC_PKC_PKCi_PRKCZ_ST	Q15109	AGER	Q05513	PRKCZ	S399	G397R	397	Missense	proximal	-2	no	30.469	41.163	EPSD	GDSC	31.494	Gain
AGC_PKC_PKCi_PRKCZ_ST	Q15109	AGER	Q05513	PRKCZ	S400	G397R	397	Missense	distal	-3	no	22.679	36.917	EPSD	GDSC	31.494	Gain
AGC_PKC_PKCi_PRKCZ_ST	Q12933	TRAF2	Q05513	PRKCZ	S162	R164Q	164	Missense	proximal	2	no	37.114	29.245	EPSD	GDSC;CCLE	31.494	Loss
AGC_PKC_PKCi_PRKCZ_ST	Q12933	TRAF2	Q05513	PRKCZ	S162	P169L	169	Missense	distal	7	no	37.114	34.584	EPSD	GDSC;CCLE	31.494	Down-regulation
AGC_PKC_PKCi_PRKCZ_ST	Q12933	TRAF2	Q05513	PRKCZ	S262	H263R	263	Missense	proximal	1	no	33.818	34.993	EPSD	GDSC;CCLE	31.494	Up-regulation
AGC_PKC_PKCi_PRKCZ_ST	Q12933	TRAF2	Q05513	PRKCZ	S262	G259A	259	Missense	distal	-3	no	33.818	31.864	EPSD	GDSC;CCLE	31.494	Down-regulation
AGC_PKC_PKCi_PRKCZ_ST	Q12933	TRAF2	Q05513	PRKCZ	S274	A280S	280	Missense	distal	6	no	37.917	36.353	EPSD	GDSC;CCLE	31.494	Down-regulation
AGC_PKC_PKCi_PRKCZ_ST	Q12933	TRAF2	Q05513	PRKCZ	S274	T279M	279	Missense	distal	5	no	37.917	38.171	EPSD	GDSC;CCLE	31.494	Up-regulation
AGC_PKC_PKCi_PRKCZ_ST	P14598	NCF1	Q05513	PRKCZ	T93	Q91K	91	Missense	proximal	-2	no	27.383	32.144	EPSD	GDSC;CCLE	31.494	Gain
AGC_PKC_PKCi_PRKCZ_ST	P14598	NCF1	Q05513	PRKCZ	S320	Y324H	324	Missense	distal	4	no	55.231	57.661	EPSD	GDSC;CCLE	31.494	Up-regulation
AGC_PKC_PKCi_PRKCZ_ST	P14598	NCF1	Q05513	PRKCZ	S328	Y324H	324	Missense	distal	-4	no	37.308	37.194	EPSD	GDSC;CCLE	31.494	Down-regulation
AGC_PKC_PKCi_PRKCZ_ST	Q04206	RELA	Q05513	PRKCZ	S238	D243Y	243	Missense	distal	5	no	40.708	40.570	EPSD	GDSC;CCLE	31.494	Down-regulation
AGC_PKC_PKCi_PRKCZ_ST	Q04206	RELA	Q05513	PRKCZ	T505	R509S	509	Missense	distal	4	no	44.864	43.637	EPSD	GDSC;CCLE	31.494	Down-regulation
Other_PLK_PLK2_PLK3_ST	P15336	ATF2	Q9H4B4	PLK3	T69	V63A	63	Missense	distal	-6	no	16.687	18.056	PhosphoSitePlus;EPSD	GDSC;CCLE	8.404	Up-regulation
Other_PLK_PLK2_PLK3_ST	P15336	ATF2	Q9H4B4	PLK3	S127	Q134H	134	Missense	distal	7	no	10.839	10.345	EPSD	GDSC;CCLE	8.404	Down-regulation
Other_PLK_PLK2_PLK3_ST	P15336	ATF2	Q9H4B4	PLK3	T336	R342H	342	Missense	distal	6	no	8.857	9.433	EPSD	GDSC;CCLE	8.404	Up-regulation
Other_PLK_PLK2_PLK3_ST	P15336	ATF2	Q9H4B4	PLK3	T336	H331L	331	Missense	distal	-5	no	8.857	8.396	EPSD	GDSC;CCLE	8.404	Loss
Other_PLK_PLK2_PLK3_ST	P15336	ATF2	Q9H4B4	PLK3	S442	S438T	438	Missense	distal	-4	no	9.235	9.489	EPSD	GDSC	8.404	Up-regulation
Other_PLK_PLK2_PLK3_ST	O96017	CHEK2	Q9H4B4	PLK3	S73	S73F	73	Missense	central	0	yes	16.249	0.000	PhosphoSitePlus;EPSD	GDSC;CCLE	8.404	Loss
Other_PLK_PLK2_PLK3_ST	P11388	TOP2A	Q9H4B4	PLK3	S230	L231P	231	Missense	proximal	1	no	11.179	11.090	EPSD	GDSC;CCLE	8.404	Down-regulation
Other_PLK_PLK2_PLK3_ST	P11388	TOP2A	Q9H4B4	PLK3	T898	K893R	893	Missense	distal	-5	no	8.855	8.656	EPSD	GDSC	8.404	Down-regulation
Other_PLK_PLK2_PLK3_ST	P11388	TOP2A	Q9H4B4	PLK3	T898	A903D	903	Missense	distal	5	no	8.855	9.293	EPSD	GDSC;CCLE	8.404	Up-regulation
Other_PLK_PLK2_PLK3_ST	P11388	TOP2A	Q9H4B4	PLK3	T950	L944S	944	Missense	distal	-6	no	9.241	12.065	EPSD	GDSC;CCLE	8.404	Up-regulation
Other_PLK_PLK2_PLK3_ST	P11388	TOP2A	Q9H4B4	PLK3	T1343	S1337L	1337	Missense	distal	-6	no	22.301	19.478	PhosphoSitePlus	GDSC	8.404	Down-regulation
Other_PLK_PLK2_PLK3_ST	P11388	TOP2A	Q9H4B4	PLK3	S1393	S1392*	1392	Missense	proximal	-1	no	9.666	10.282	EPSD	GDSC	8.404	Up-regulation
Other_PLK_PLK2_PLK3_ST	P11388	TOP2A	Q9H4B4	PLK3	S1504	V1506M	1506	Missense	proximal	2	no	8.471	9.647	EPSD	GDSC;CCLE	8.404	Up-regulation
Other_PLK_PLK2_PLK3_ST	P60484	PTEN	Q9H4B4	PLK3	S294	Q298*	298	Missense	distal	4	no	11.776	12.557	EPSD	GDSC	8.404	Up-regulation
Other_PLK_PLK2_PLK3_ST	P60484	PTEN	Q9H4B4	PLK3	S294	E299*	299	Missense	distal	5	no	11.776	13.270	EPSD	GDSC	8.404	Up-regulation
Other_PLK_PLK2_PLK3_ST	O43852	CALU	Q9H4B4	PLK3	S35	N40I	40	Missense	distal	5	no	10.177	10.708	EPSD	GDSC;CCLE	8.404	Up-regulation
Other_PLK_PLK2_PLK3_ST	O43852	CALU	Q9H4B4	PLK3	S44	N40I	40	Missense	distal	-4	no	16.153	18.228	PhosphoSitePlus;EPSD	GDSC;CCLE	8.404	Up-regulation
Other_PLK_PLK2_PLK3_ST	O43852	CALU	Q9H4B4	PLK3	T254	P260L	260	Missense	distal	6	no	16.980	16.932	EPSD;PhosphoSitePlus	GDSC;CCLE	8.404	Down-regulation
Other_PLK_PLK2_PLK3_ST	P08238	HSP90AB1	Q9H4B4	PLK3	S58	P62H	62	Missense	distal	4	no	11.600	11.592	EPSD	GDSC;CCLE	8.404	Down-regulation
Other_PLK_PLK2_PLK3_ST	P08238	HSP90AB1	Q9H4B4	PLK3	S63	P62H	62	Missense	proximal	-1	no	9.180	9.273	EPSD	GDSC;CCLE	8.404	Up-regulation
Other_PLK_PLK2_PLK3_ST	P08238	HSP90AB1	Q9H4B4	PLK3	T297	G302*	302	Missense	distal	5	no	11.067	11.634	EPSD	GDSC	8.404	Up-regulation
Other_PLK_PLK2_PLK3_ST	P08238	HSP90AB1	Q9H4B4	PLK3	T579	V575A	575	Missense	distal	-4	no	10.122	11.357	EPSD	GDSC;CCLE	8.404	Up-regulation
Other_PLK_PLK2_PLK3_ST	P08238	HSP90AB1	Q9H4B4	PLK3	T616	M617R	617	Missense	proximal	1	no	9.868	9.516	EPSD	GDSC;CCLE	8.404	Down-regulation
Other_PLK_PLK2_PLK3_ST	P08238	HSP90AB1	Q9H4B4	PLK3	T616	A610T	610	Missense	distal	-6	no	9.868	9.160	EPSD	GDSC;CCLE	8.404	Down-regulation
Other_PLK_PLK2_PLK3_ST	P06748	NPM1	Q9H4B4	PLK3	S139	A144T	144	Missense	distal	5	no	10.224	9.855	EPSD	GDSC;CCLE	8.404	Down-regulation
Other_PLK_PLK2_PLK3_ST	P06748	NPM1	Q9H4B4	PLK3	S143	A144T	144	Missense	proximal	1	no	9.238	8.040	EPSD	GDSC;CCLE	8.404	Loss
Other_PLK_PLK2_PLK3_ST	P06748	NPM1	Q9H4B4	PLK3	S222	P220L	220	Missense	proximal	-2	no	9.608	11.773	EPSD	GDSC;CCLE	8.404	Up-regulation
Other_PLK_PLK2_PLK3_ST	P06748	NPM1	Q9H4B4	PLK3	S243	E245Q	245	Missense	proximal	2	no	10.094	7.817	EPSD	GDSC	8.404	Loss
Other_PLK_PLK2_PLK3_ST	P30307	CDC25C	Q9H4B4	PLK3	T40	E34Q	34	Missense	distal	-6	no	9.545	6.832	EPSD	GDSC;CCLE	8.404	Loss
Other_PLK_PLK2_PLK3_ST	P04637	TP53	Q9H4B4	PLK3	T150	Q144*	144	Missense	distal	-6	no	9.520	9.709	EPSD	GDSC	8.404	Up-regulation
Other_PLK_PLK2_PLK3_ST	P04637	TP53	Q9H4B4	PLK3	T150	W146*	146	Missense	distal	-4	no	9.520	9.635	EPSD	GDSC	8.404	Up-regulation
Other_PLK_PLK2_PLK3_ST	P04637	TP53	Q9H4B4	PLK3	S183	S183*	183	Missense	central	0	yes	12.054	0.000	EPSD	GDSC	8.404	Loss
Other_PLK_PLK2_PLK3_ST	P04637	TP53	Q9H4B4	PLK3	S183	E180*	180	Missense	distal	-3	no	12.054	6.829	EPSD	GDSC	8.404	Loss
Other_PLK_PLK2_PLK3_ST	P04637	TP53	Q9H4B4	PLK3	S315	Q317*	317	Missense	proximal	2	no	11.511	10.581	EPSD	GDSC	8.404	Down-regulation
Other_PLK_PLK2_PLK3_ST	P04637	TP53	Q9H4B4	PLK3	S315	K319*	319	Missense	distal	4	no	11.511	11.824	EPSD	GDSC	8.404	Up-regulation
Other_PLK_PLK2_PLK3_ST	P14635	CCNB1	Q9H4B4	PLK3	S133	E140D	140	Missense	distal	7	no	15.446	15.143	PhosphoSitePlus	GDSC;CCLE	8.404	Down-regulation
Other_PLK_PLK2_PLK3_ST	P14635	CCNB1	Q9H4B4	PLK3	S133	E140Q	140	Missense	distal	7	no	15.446	15.064	PhosphoSitePlus	GDSC;CCLE	8.404	Down-regulation
Other_PLK_PLK2_PLK3_ST	Q14790	CASP8	Q9H4B4	PLK3	S375	S375P	375	Missense	central	0	yes	9.500	0.000	EPSD	GDSC	8.404	Loss
Other_PLK_PLK2_PLK3_ST	Q99986	VRK1	Q9H4B4	PLK3	S342	N346Y	346	Missense	distal	4	no	16.360	17.039	PhosphoSitePlus	GDSC;CCLE	8.404	Up-regulation
Other_PLK_PLK2_PLK3_ST	P30304	CDC25A	Q9H4B4	PLK3	T80	G75C	75	Missense	distal	-5	no	16.479	15.906	PhosphoSitePlus	GDSC;CCLE	8.404	Down-regulation
Other_PLK_PLK2_PLK3_ST	P30304	CDC25A	Q9H4B4	PLK3	S239	T233P	233	Missense	distal	-6	no	10.258	9.889	EPSD	GDSC	8.404	Down-regulation
Other_PLK_PLK2_PLK3_ST	Q16143	SNCB	Q9H4B4	PLK3	S118	E117K	117	Missense	proximal	-1	no	12.203	13.143	PhosphoSitePlus	GDSC;CCLE	8.404	Up-regulation
Other_PLK_PLK2_PLK3_ST	Q16665	HIF1A	Q9H4B4	PLK3	S58	S58F	58	Missense	central	0	yes	11.014	0.000	EPSD	GDSC;CCLE	8.404	Loss
Other_PLK_PLK2_PLK3_ST	Q16665	HIF1A	Q9H4B4	PLK3	T63	S58F	58	Missense	distal	-5	no	9.042	9.260	EPSD	GDSC;CCLE	8.404	Up-regulation
Other_PLK_PLK2_PLK3_ST	Q16665	HIF1A	Q9H4B4	PLK3	T290	S284C	284	Missense	distal	-6	no	11.599	10.667	EPSD	GDSC	8.404	Down-regulation
Other_PLK_PLK2_PLK3_ST	Q16665	HIF1A	Q9H4B4	PLK3	S510	Q508*	508	Missense	proximal	-2	no	8.689	4.688	EPSD	GDSC	8.404	Loss
Other_PLK_PLK2_PLK3_ST	Q16665	HIF1A	Q9H4B4	PLK3	S515	Q508*	508	Missense	distal	-7	no	11.169	11.797	EPSD	GDSC	8.404	Up-regulation
Other_PLK_PLK2_PLK3_ST	Q16665	HIF1A	Q9H4B4	PLK3	S525	M527T	527	Missense	proximal	2	no	9.569	9.407	EPSD	GDSC	8.404	Down-regulation
Other_PLK_PLK2_PLK3_ST	Q16665	HIF1A	Q9H4B4	PLK3	T652	Y659N	659	Missense	distal	7	no	8.898	7.517	EPSD	GDSC;CCLE	8.404	Loss
Other_PLK_PLK2_PLK3_ST	Q16665	HIF1A	Q9H4B4	PLK3	S657	Y659N	659	Missense	proximal	2	no	15.961	16.041	EPSD;PhosphoSitePlus	GDSC;CCLE	8.404	Up-regulation
Other_PLK_PLK2_PLK3_ST	Q16665	HIF1A	Q9H4B4	PLK3	S687	P685S	685	Missense	proximal	-2	no	7.428	8.513	EPSD	GDSC;CCLE	8.404	Gain
Other_PLK_PLK2_PLK3_ST	Q07817	BCL2L1	Q9H4B4	PLK3	S49	S43L	43	Missense	distal	-6	no	16.063	13.240	PhosphoSitePlus	GDSC;CCLE	8.404	Down-regulation
Other_PLK_PLK2_PLK3_ST	Q07817	BCL2L1	Q9H4B4	PLK3	S49	P55S	55	Missense	distal	6	no	16.063	15.768	PhosphoSitePlus	GDSC;CCLE	8.404	Down-regulation
Other_PLK_PLK2_PLK3_ST	P37840	SNCA	Q9H4B4	PLK3	S129	M127I	127	Missense	proximal	-2	no	13.118	8.188	PhosphoSitePlus	GDSC	8.404	Loss
Other_PLK_PLK2_PLK3_ST	P37840	SNCA	Q9H4B4	PLK3	S129	E130G	130	Missense	proximal	1	no	13.118	14.247	PhosphoSitePlus	GDSC	8.404	Up-regulation
CMGC_MAPK_JNK_MAPK10_ST	P54259	ATN1	P53779	MAPK10	S439	Q440*	440	Missense	proximal	1	no	-0.001	0.000	EPSD	GDSC	0.000	Gain
CMGC_MAPK_JNK_MAPK10_ST	P54259	ATN1	P53779	MAPK10	S632	P633S	633	Missense	proximal	1	no	0.023	-0.003	EPSD	GDSC;CCLE	0.000	Loss
Other_NEK_NEK1_NEK1_ST	O14777	NDC80	Q96PY6	NEK1	T34	G28D	28	Missense	distal	-6	no	2.401	2.438	EPSD	GDSC	2.106	Up-regulation
CMGC_CDK_CCRK_CDK20_ST	P24941	CDK2	Q8IZL9	CDK20	T160	P155L	155	Missense	distal	-5	no	5.811	5.090	PhosphoSitePlus	GDSC;CCLE	1.958	Down-regulation
CMGC_CDK_CCRK_CDK20_ST	P24941	CDK2	Q8IZL9	CDK20	T221	D223G	223	Missense	proximal	2	no	2.458	2.461	EPSD	GDSC	1.958	Up-regulation
TK_Axl_AXL_Y	P07947	YES1	P30530	AXL	Y32	Y32C	32	Missense	central	0	yes	0.004	0.000	EPSD	GDSC	0.002	Loss
CAMK_DAPK_DAPK_DAPK3_ST	O43293	DAPK3	O43293	DAPK3	T306	I307T	307	Missense	proximal	1	no	11.911	11.870	PhosphoSitePlus;EPSD	GDSC;CCLE	6.449	Down-regulation
CAMK_DAPK_DAPK_DAPK3_ST	O43293	DAPK3	O43293	DAPK3	S311	I307T	307	Missense	distal	-4	no	11.084	11.236	EPSD;PhosphoSitePlus	GDSC;CCLE	6.449	Up-regulation
CAMK_DAPK_DAPK_DAPK3_ST	O43293	DAPK3	O43293	DAPK3	S414	R411H	411	Missense	distal	-3	no	6.695	2.163	EPSD	GDSC;CCLE	6.449	Loss
CAMK_DAPK_DAPK_DAPK3_ST	O14950	MYL12B	O43293	DAPK3	T19	R14H	14	Missense	distal	-5	no	10.367	8.491	EPSD;PhosphoSitePlus	GDSC;CCLE	6.449	Down-regulation
CAMK_DAPK_DAPK_DAPK3_ST	O14950	MYL12B	O43293	DAPK3	T19	Q16*	16	Missense	distal	-3	no	10.367	6.424	EPSD;PhosphoSitePlus	GDSC	6.449	Loss
CAMK_DAPK_DAPK_DAPK3_ST	O14950	MYL12B	O43293	DAPK3	S20	R14H	14	Missense	distal	-6	no	11.851	12.651	PhosphoSitePlus;EPSD	GDSC;CCLE	6.449	Up-regulation
CAMK_DAPK_DAPK_DAPK3_ST	O14950	MYL12B	O43293	DAPK3	S20	Q16*	16	Missense	distal	-4	no	11.851	11.535	PhosphoSitePlus;EPSD	GDSC	6.449	Down-regulation
CAMK_DAPK_DAPK_DAPK3_ST	P04637	TP53	O43293	DAPK3	S215	R209*	209	Missense	distal	-6	no	5.367	6.883	EPSD	GDSC	6.449	Gain
CAMK_DAPK_DAPK_DAPK3_ST	P04637	TP53	O43293	DAPK3	S362	G360V	360	Missense	proximal	-2	no	7.685	7.330	EPSD	GDSC;CCLE	6.449	Down-regulation
CAMK_DAPK_DAPK_DAPK3_ST	P04637	TP53	O43293	DAPK3	S366	G360V	360	Missense	distal	-6	no	8.392	8.365	EPSD	GDSC;CCLE	6.449	Down-regulation
CAMK_DAPK_DAPK_DAPK3_ST	P38936	CDKN1A	O43293	DAPK3	S31	L37P	37	Missense	distal	6	no	6.680	6.673	EPSD	GDSC	6.449	Down-regulation
CAMK_DAPK_DAPK_DAPK3_ST	P38936	CDKN1A	O43293	DAPK3	S31	Q29R	29	Missense	proximal	-2	no	6.680	8.363	EPSD	GDSC;CCLE	6.449	Up-regulation
CAMK_DAPK_DAPK_DAPK3_ST	P38936	CDKN1A	O43293	DAPK3	T145	R143Q	143	Missense	proximal	-2	no	14.198	12.515	PhosphoSitePlus	GDSC;CCLE	6.449	Down-regulation
CAMK_DAPK_DAPK_DAPK3_ST	P38936	CDKN1A	O43293	DAPK3	S146	R143Q	143	Missense	distal	-3	no	6.558	2.426	EPSD	GDSC;CCLE	6.449	Loss
TK_FGFR_FGFR2_Y	P35222	CTNNB1	P21802	FGFR2	Y142	A135V	135	Missense	distal	-7	no	3.637	3.652	PhosphoSitePlus	GDSC;CCLE	1.189	Up-regulation
TK_FGFR_FGFR2_Y	P60484	PTEN	P21802	FGFR2	Y240	R233*	233	Missense	distal	-7	no	3.649	3.562	PhosphoSitePlus	GDSC	1.189	Down-regulation
TK_FGFR_FGFR2_Y	P62993	GRB2	P21802	FGFR2	Y7	T12A	12	Missense	distal	5	no	1.633	1.408	EPSD	GDSC;CCLE	1.189	Down-regulation
CAMK_CAMKL_BRSK_BRSK1_ST	Q8TDC3	BRSK1	Q8TDC3-2	BRSK1	S275	Q280R	280	Missense	distal	5	no	0.690	0.699	EPSD	GDSC;CCLE	0.579	Up-regulation
CAMK_CAMKL_BRSK_BRSK1_ST	Q8TDC3	BRSK1	Q8TDC3-2	BRSK1	S442	G439C	439	Missense	distal	-3	no	0.607	0.609	EPSD	GDSC	0.579	Up-regulation
CAMK_CAMKL_BRSK_BRSK1_ST	Q8TDC3	BRSK1	Q8TDC3-2	BRSK1	S555	F560L	560	Missense	distal	5	no	0.546	0.608	EPSD	GDSC;CCLE	0.579	Gain
CAMK_CAMKL_BRSK_BRSK1_ST	P30291	WEE1	Q8TDC3-2	BRSK1	S571	A577P	577	Missense	distal	6	no	0.650	0.718	EPSD	GDSC;CCLE	0.579	Up-regulation
CAMK_CAMKL_BRSK_BRSK1_ST	P23258	TUBG1	Q8TDC3-2	BRSK1	S131	S131I	131	Missense	central	0	yes	1.301	0.000	PhosphoSitePlus	GDSC;CCLE	0.579	Loss
CAMK_CAMKL_BRSK_BRSK1_ST	P30305	CDC25B	Q8TDC3-2	BRSK1	S151	V154A	154	Missense	distal	3	no	0.564	0.594	EPSD	GDSC	0.579	Gain
CAMK_CAMKL_BRSK_BRSK1_ST	P30305	CDC25B	Q8TDC3-2	BRSK1	S375	R369C	369	Missense	distal	-6	no	1.213	1.168	PhosphoSitePlus	GDSC	0.579	Down-regulation
CAMK_CAMKL_BRSK_BRSK1_ST	P30305	CDC25B	Q8TDC3-2	BRSK1	S397	Y396*	396	Missense	proximal	-1	no	0.696	0.726	EPSD	GDSC	0.579	Up-regulation
CAMK_CAMKL_BRSK_BRSK1_ST	P30307	CDC25C	Q8TDC3-2	BRSK1	S451	R458Q	458	Missense	distal	7	no	0.689	0.708	EPSD	GDSC;CCLE	0.579	Up-regulation
AGC_Akt_AKT3_ST	Q9UKV8	AGO2	Q9Y243	AKT3	S798	A801E	801	Missense	distal	3	no	3.376	3.259	EPSD	GDSC;CCLE	2.840	Down-regulation
AGC_Akt_AKT3_ST	O15119	TBX3	Q9Y243	AKT3	S432	D429E	429	Missense	distal	-3	no	3.279	3.077	EPSD	GDSC;CCLE	2.840	Down-regulation
AGC_Akt_AKT3_ST	P15056	BRAF	Q9Y243	AKT3	S365	D361G	361	Missense	distal	-4	no	9.586	9.579	PhosphoSitePlus;EPSD	GDSC;CCLE	2.840	Down-regulation
AGC_Akt_AKT3_ST	Q7Z589	EMSY	Q9Y243	AKT3	S173	A175T	175	Missense	proximal	2	no	3.048	2.780	EPSD	GDSC	2.840	Loss
AGC_Akt_AKT3_ST	Q7Z589	EMSY	Q9Y243	AKT3	S173	N177S	177	Missense	distal	4	no	3.048	3.168	EPSD	GDSC	2.840	Up-regulation
AGC_Akt_AKT3_ST	Q7Z589	EMSY	Q9Y243	AKT3	T207	S213F	213	Missense	distal	6	no	4.707	4.717	PhosphoSitePlus;EPSD	GDSC	2.840	Up-regulation
AGC_Akt_AKT3_ST	Q7Z589	EMSY	Q9Y243	AKT3	S209	S213F	213	Missense	distal	4	no	4.066	3.968	EPSD;PhosphoSitePlus	GDSC	2.840	Down-regulation
AGC_Akt_AKT3_ST	Q7Z589	EMSY	Q9Y243	AKT3	S210	S213F	213	Missense	distal	3	no	3.689	3.572	EPSD	GDSC	2.840	Down-regulation
AGC_Akt_AKT3_ST	Q7Z589	EMSY	Q9Y243	AKT3	S211	S213F	213	Missense	proximal	2	no	4.644	4.771	EPSD	GDSC	2.840	Up-regulation
AGC_Akt_AKT3_ST	Q7Z589	EMSY	Q9Y243	AKT3	S1213	C1207R	1207	Missense	distal	-6	no	2.779	2.850	EPSD	GDSC	2.840	Gain
AGC_Akt_AKT3_ST	Q7Z589	EMSY	Q9Y243	AKT3	T1216	P1214S	1214	Missense	proximal	-2	no	1.929	2.874	EPSD	GDSC	2.840	Gain
STE_STE11_MEKK1_MAP3K1_ST	P46531	NOTCH1	Q13233	MAP3K1	T2132	P2133S	2133	Missense	proximal	1	no	2.608	2.265	EPSD	GDSC	2.285	Loss
STE_STE11_MEKK1_MAP3K1_ST	P46531	NOTCH1	Q13233	MAP3K1	S2516	S2523*	2523	Missense	distal	7	no	2.280	2.296	EPSD	GDSC	2.285	Gain
TK_ALK_ALK_Y	P23246	SFPQ	Q9UM73	ALK	Y293	E290D	290	Missense	distal	-3	no	5.156	5.170	PhosphoSitePlus	GDSC;CCLE	2.462	Up-regulation
TK_ALK_ALK_Y	P40763	STAT3	Q9UM73	ALK	Y705	C712Y	712	Missense	distal	7	no	5.411	5.504	PhosphoSitePlus	GDSC;CCLE	2.462	Up-regulation
TK_ALK_ALK_Y	Q06124	PTPN11	Q9UM73	ALK	Y584	V583M	583	Missense	proximal	-1	no	4.823	4.715	EPSD	GDSC;CCLE	2.462	Down-regulation
AGC_RSK_MSK_RPS6KA5_ST	P16220	CREB1	O75582	RPS6KA5	S108	S111L	111	Missense	distal	3	no	1.753	1.762	EPSD	GDSC;CCLE	1.456	Up-regulation
AGC_RSK_MSK_RPS6KA5_ST	P16220	CREB1	O75582	RPS6KA5	S114	S111L	111	Missense	distal	-3	no	1.594	1.419	EPSD	GDSC;CCLE	1.456	Loss
AGC_RSK_MSK_RPS6KA5_ST	O75582	RPS6KA5	O75582	RPS6KA5	S750	R756H	756	Missense	distal	6	no	1.561	1.566	EPSD;PhosphoSitePlus	GDSC;CCLE	1.456	Up-regulation
AGC_RSK_MSK_RPS6KA5_ST	O75582	RPS6KA5	O75582	RPS6KA5	S750	T755P	755	Missense	distal	5	no	1.561	1.567	EPSD;PhosphoSitePlus	GDSC;CCLE	1.456	Up-regulation
AGC_RSK_MSK_RPS6KA5_ST	O75582	RPS6KA5	O75582	RPS6KA5	S758	R756H	756	Missense	proximal	-2	no	2.440	0.861	EPSD;PhosphoSitePlus	GDSC;CCLE	1.456	Loss
AGC_RSK_MSK_RPS6KA5_ST	O75582	RPS6KA5	O75582	RPS6KA5	S758	T755P	755	Missense	distal	-3	no	2.440	2.419	EPSD;PhosphoSitePlus	GDSC;CCLE	1.456	Down-regulation
AGC_RSK_MSK_RPS6KA5_ST	O75582	RPS6KA5	O75582	RPS6KA5	S759	R756H	756	Missense	distal	-3	no	2.201	1.287	EPSD	GDSC;CCLE	1.456	Loss
AGC_RSK_MSK_RPS6KA5_ST	O75582	RPS6KA5	O75582	RPS6KA5	S759	T755P	755	Missense	distal	-4	no	2.201	2.164	EPSD	GDSC;CCLE	1.456	Down-regulation
AGC_RSK_MSK_RPS6KA5_ST	P10276	RARA	O75582	RPS6KA5	S219	D226N	226	Missense	distal	7	no	2.659	2.654	EPSD	GDSC;CCLE	1.456	Down-regulation
AGC_RSK_MSK_RPS6KA5_ST	P10276	RARA	O75582	RPS6KA5	S219	S219C	219	Missense	central	0	yes	2.659	0.000	EPSD	GDSC	1.456	Loss
AGC_RSK_MSK_RPS6KA5_ST	P54253	ATXN1	O75582	RPS6KA5	S25	T32S	32	Missense	distal	7	no	1.538	1.487	EPSD	GDSC	1.456	Down-regulation
AGC_RSK_MSK_RPS6KA5_ST	P54253	ATXN1	O75582	RPS6KA5	S25	I19T	19	Missense	distal	-6	no	1.538	1.546	EPSD	GDSC	1.456	Up-regulation
AGC_RSK_MSK_RPS6KA5_ST	P54253	ATXN1	O75582	RPS6KA5	S26	T32S	32	Missense	distal	6	no	2.709	2.698	EPSD	GDSC	1.456	Down-regulation
AGC_RSK_MSK_RPS6KA5_ST	P54253	ATXN1	O75582	RPS6KA5	S26	I19T	19	Missense	distal	-7	no	2.709	2.725	EPSD	GDSC	1.456	Up-regulation
AGC_RSK_MSK_RPS6KA5_ST	P54253	ATXN1	O75582	RPS6KA5	S82	D86N	86	Missense	distal	4	no	1.492	1.496	EPSD	GDSC;CCLE	1.456	Up-regulation
AGC_RSK_MSK_RPS6KA5_ST	P54253	ATXN1	O75582	RPS6KA5	S82	L81F	81	Missense	proximal	-1	no	1.492	1.486	EPSD	GDSC;CCLE	1.456	Down-regulation
AGC_RSK_MSK_RPS6KA5_ST	P54253	ATXN1	O75582	RPS6KA5	S775	E778Q	778	Missense	distal	3	no	3.524	3.528	PhosphoSitePlus	GDSC;CCLE	1.456	Up-regulation
AGC_RSK_MSK_RPS6KA5_ST	P18846	ATF1	O75582	RPS6KA5	S189	R182L	182	Missense	distal	-7	no	1.428	1.502	EPSD	GDSC;CCLE	1.456	Gain
AGC_RSK_MSK_RPS6KA5_ST	Q04206	RELA	O75582	RPS6KA5	S203	V199A	199	Missense	distal	-4	no	2.479	2.401	EPSD	GDSC;CCLE	1.456	Down-regulation
AGC_RSK_MSK_RPS6KA5_ST	Q04206	RELA	O75582	RPS6KA5	S238	D243Y	243	Missense	distal	5	no	3.013	3.014	EPSD	GDSC;CCLE	1.456	Up-regulation
AGC_RSK_MSK_RPS6KA5_ST	Q9H4A3	WNK1	O75582	RPS6KA5	S167	L171F	171	Missense	distal	4	no	1.931	1.920	EPSD	GDSC;CCLE	1.456	Down-regulation
AGC_RSK_MSK_RPS6KA5_ST	Q9H4A3	WNK1	O75582	RPS6KA5	S231	D224H	224	Missense	distal	-7	no	2.509	2.493	EPSD	GDSC;CCLE	1.456	Down-regulation
AGC_RSK_MSK_RPS6KA5_ST	Q9H4A3	WNK1	O75582	RPS6KA5	S231	V235A	235	Missense	distal	4	no	2.509	2.551	EPSD	GDSC;CCLE	1.456	Up-regulation
AGC_RSK_MSK_RPS6KA5_ST	Q9H4A3	WNK1	O75582	RPS6KA5	S231	D224G	224	Missense	distal	-7	no	2.509	2.501	EPSD	GDSC;CCLE	1.456	Down-regulation
AGC_RSK_MSK_RPS6KA5_ST	Q9H4A3	WNK1	O75582	RPS6KA5	S563	V562A	562	Missense	proximal	-1	no	2.710	2.742	EPSD	GDSC;CCLE	1.456	Up-regulation
AGC_RSK_MSK_RPS6KA5_ST	Q9H4A3	WNK1	O75582	RPS6KA5	S1297	S1300F	1300	Missense	distal	3	no	1.548	1.556	EPSD	GDSC;CCLE	1.456	Up-regulation
AGC_RSK_MSK_RPS6KA5_ST	Q9H4A3	WNK1	O75582	RPS6KA5	S1300	S1300F	1300	Missense	central	0	yes	1.518	0.000	EPSD	GDSC;CCLE	1.456	Loss
AGC_RSK_MSK_RPS6KA5_ST	Q9H4A3	WNK1	O75582	RPS6KA5	S1528	S1535R	1535	Missense	distal	7	no	1.518	1.503	EPSD	GDSC	1.456	Down-regulation
AGC_RSK_MSK_RPS6KA5_ST	Q9H4A3	WNK1	O75582	RPS6KA5	S2121	P2116A	2116	Missense	distal	-5	no	1.473	1.491	EPSD	GDSC;CCLE	1.456	Up-regulation
TK_EGFR_EGFR_Y	P52735	VAV2	P00533	EGFR	Y142	D139G	139	Missense	distal	-3	no	11.200	8.641	PhosphoSitePlus;EPSD	GDSC	6.466	Down-regulation
TK_EGFR_EGFR_Y	P52735	VAV2	P00533	EGFR	Y159	D166Y	166	Missense	distal	7	no	15.767	15.711	EPSD;PhosphoSitePlus	GDSC;CCLE	6.466	Down-regulation
TK_EGFR_EGFR_Y	P52735	VAV2	P00533	EGFR	Y426	K422E	422	Missense	distal	-4	no	5.487	7.600	EPSD	GDSC;CCLE	6.466	Gain
TK_EGFR_EGFR_Y	Q8NFJ5	GPRC5A	P00533	EGFR	Y317	Y317C	317	Missense	central	0	yes	9.261	0.000	EPSD;PhosphoSitePlus	GDSC;CCLE	6.466	Loss
TK_EGFR_EGFR_Y	Q8NFJ5	GPRC5A	P00533	EGFR	Y320	Y317C	317	Missense	distal	-3	no	8.152	6.722	PhosphoSitePlus;EPSD	GDSC;CCLE	6.466	Down-regulation
TK_EGFR_EGFR_Y	P29353	SHC1	P00533	EGFR	Y349	Y349H	349	Missense	central	0	yes	12.290	0.000	EPSD	GDSC;CCLE	6.466	Loss
TK_EGFR_EGFR_Y	P29353	SHC1	P00533	EGFR	Y350	Y349H	349	Missense	proximal	-1	no	13.414	14.707	EPSD	GDSC;CCLE	6.466	Up-regulation
TK_EGFR_EGFR_Y	P00533	EGFR	P00533	EGFR	Y1092	T1085N	1085	Missense	distal	-7	no	10.686	10.399	EPSD;PhosphoSitePlus	GDSC;CCLE	6.466	Down-regulation
TK_EGFR_EGFR_Y	P19174	PLCG1	P00533	EGFR	Y783	E785K	785	Missense	proximal	2	no	8.649	6.751	EPSD;PhosphoSitePlus	GDSC;CCLE	6.466	Down-regulation
TK_EGFR_EGFR_Y	Q05397	PTK2	P00533	EGFR	Y407	T406I	406	Missense	proximal	-1	no	12.749	13.428	EPSD	GDSC;CCLE	6.466	Up-regulation
TK_EGFR_EGFR_Y	Q05397	PTK2	P00533	EGFR	Y407	P410H	410	Missense	distal	3	no	12.749	12.595	EPSD	GDSC;CCLE	6.466	Down-regulation
TK_EGFR_EGFR_Y	Q13480	GAB1	P00533	EGFR	Y373	A366T	366	Missense	distal	-7	no	9.862	9.763	EPSD;PhosphoSitePlus	GDSC;CCLE	6.466	Down-regulation
TK_EGFR_EGFR_Y	Q13480	GAB1	P00533	EGFR	Y373	D370G	370	Missense	distal	-3	no	9.862	7.304	EPSD;PhosphoSitePlus	GDSC;CCLE	6.466	Down-regulation
TK_EGFR_EGFR_Y	Q13480	GAB1	P00533	EGFR	Y373	C374R	374	Missense	proximal	1	no	9.862	8.035	EPSD;PhosphoSitePlus	GDSC;CCLE	6.466	Down-regulation
TK_EGFR_EGFR_Y	Q13480	GAB1	P00533	EGFR	Y406	A411E	411	Missense	distal	5	no	12.131	12.066	PhosphoSitePlus;EPSD	GDSC	6.466	Down-regulation
TK_EGFR_EGFR_Y	Q13480	GAB1	P00533	EGFR	Y447	L443P	443	Missense	distal	-4	no	12.802	13.305	EPSD;PhosphoSitePlus	GDSC;CCLE	6.466	Up-regulation
TK_EGFR_EGFR_Y	Q13480	GAB1	P00533	EGFR	Y472	P466T	466	Missense	distal	-6	no	14.196	14.217	EPSD;PhosphoSitePlus	GDSC;CCLE	6.466	Up-regulation
TK_EGFR_EGFR_Y	O14939	PLD2	P00533	EGFR	Y296	S294N	294	Missense	proximal	-2	no	8.334	9.198	PhosphoSitePlus	GDSC;CCLE	6.466	Up-regulation
TK_EGFR_EGFR_Y	P40818	USP8	P00533	EGFR	Y717	T723S	723	Missense	distal	6	no	9.285	9.496	PhosphoSitePlus;EPSD	GDSC;CCLE	6.466	Up-regulation
TK_EGFR_EGFR_Y	P40818	USP8	P00533	EGFR	Y810	R807*	807	Missense	distal	-3	no	10.647	7.797	EPSD;PhosphoSitePlus	GDSC	6.466	Down-regulation
TK_EGFR_EGFR_Y	O00767	SCD	P00533	EGFR	Y41	M38V	38	Missense	distal	-3	no	13.605	14.063	PhosphoSitePlus;EPSD	GDSC;CCLE	6.466	Up-regulation
TK_EGFR_EGFR_Y	Q9UBN7	HDAC6	P00533	EGFR	Y570	S563T	563	Missense	distal	-7	no	9.897	10.225	PhosphoSitePlus	GDSC;CCLE	6.466	Up-regulation
TK_EGFR_EGFR_Y	Q38SD2	LRRK1	P00533	EGFR	Y971	T967M	967	Missense	distal	-4	no	11.746	11.137	PhosphoSitePlus	GDSC	6.466	Down-regulation
TK_EGFR_EGFR_Y	Q9P0J1	PDP1	P00533	EGFR	Y381	N379D	379	Missense	proximal	-2	no	10.792	10.744	PhosphoSitePlus	GDSC;CCLE	6.466	Down-regulation
TK_EGFR_EGFR_Y	O15455	TLR3	P00533	EGFR	Y858	A863T	863	Missense	distal	5	no	9.583	9.472	PhosphoSitePlus	GDSC;CCLE	6.466	Down-regulation
TK_EGFR_EGFR_Y	O15492	RGS16	P00533	EGFR	Y177	Q183R	183	Missense	distal	6	no	7.375	7.168	EPSD	GDSC;CCLE	6.466	Down-regulation
TK_EGFR_EGFR_Y	O15492	RGS16	P00533	EGFR	Y177	D179A	179	Missense	proximal	2	no	7.375	5.821	EPSD	GDSC;CCLE	6.466	Loss
TK_EGFR_EGFR_Y	P18031	PTPN1	P00533	EGFR	Y66	A69D	69	Missense	distal	3	no	12.851	12.445	PhosphoSitePlus	GDSC;CCLE	6.466	Down-regulation
TK_EGFR_EGFR_Y	P15311	EZR	P00533	EGFR	Y499	A501T	501	Missense	proximal	2	no	12.598	12.166	EPSD	GDSC;CCLE	6.466	Down-regulation
TK_EGFR_EGFR_Y	Q92529	SHC3	P00533	EGFR	Y406	G401V	401	Missense	distal	-5	no	12.044	11.940	EPSD	GDSC	6.466	Down-regulation
TK_EGFR_EGFR_Y	Q92529	SHC3	P00533	EGFR	Y406	T408M	408	Missense	proximal	2	no	12.044	11.461	EPSD	GDSC	6.466	Down-regulation
TK_EGFR_EGFR_Y	Q92529	SHC3	P00533	EGFR	Y406	G411E	411	Missense	distal	5	no	12.044	12.065	EPSD	GDSC;CCLE	6.466	Up-regulation
TK_EGFR_EGFR_Y	P14618	PKM	P00533	EGFR	Y148	M149V	149	Missense	proximal	1	no	10.187	11.410	PhosphoSitePlus	GDSC;CCLE	6.466	Up-regulation
TK_EGFR_EGFR_Y	P14618	PKM	P00533	EGFR	Y148	Y148*	148	Missense	central	0	yes	10.187	0.000	PhosphoSitePlus	GDSC	6.466	Loss
TK_EGFR_EGFR_Y	P14618	PKM	P00533	EGFR	Y148	K141I	141	Missense	distal	-7	no	10.187	9.816	PhosphoSitePlus	GDSC	6.466	Down-regulation
TK_EGFR_EGFR_Y	P14618	PKM	P00533	EGFR	Y148	Y148N	148	Missense	central	0	yes	10.187	0.000	PhosphoSitePlus	GDSC;CCLE	6.466	Loss
TK_EGFR_EGFR_Y	Q8TDY4	ASAP3	P00533	EGFR	Y76	V80M	80	Missense	distal	4	no	10.997	11.153	EPSD	GDSC	6.466	Up-regulation
TK_EGFR_EGFR_Y	Q8TDY4	ASAP3	P00533	EGFR	Y76	E71D	71	Missense	distal	-5	no	10.997	10.628	EPSD	GDSC;CCLE	6.466	Down-regulation
TK_EGFR_EGFR_Y	Q8TDY4	ASAP3	P00533	EGFR	Y535	F540L	540	Missense	distal	5	no	6.799	6.598	EPSD	GDSC;CCLE	6.466	Down-regulation
TK_EGFR_EGFR_Y	Q8TDY4	ASAP3	P00533	EGFR	Y843	T837I	837	Missense	distal	-6	no	10.611	10.606	EPSD	GDSC;CCLE	6.466	Down-regulation
TK_EGFR_EGFR_Y	Q14164	IKBKE	P00533	EGFR	Y179	D183N	183	Missense	distal	4	no	10.842	10.320	PhosphoSitePlus;EPSD	GDSC	6.466	Down-regulation
TK_EGFR_EGFR_Y	Q14164	IKBKE	P00533	EGFR	Y179	E178D	178	Missense	proximal	-1	no	10.842	10.916	PhosphoSitePlus;EPSD	GDSC;CCLE	6.466	Up-regulation
STE_STE20_PAKA_PAK2_ST	Q53QZ3	ARHGAP15	Q13177	PAK2	S199	C197R	197	Missense	proximal	-2	no	6.318	17.920	EPSD	GDSC;CCLE	14.606	Gain
STE_STE20_PAKA_PAK2_ST	Q53QZ3	ARHGAP15	Q13177	PAK2	S233	E229D	229	Missense	distal	-4	no	18.208	20.582	EPSD	GDSC;CCLE	14.606	Up-regulation
STE_STE20_PAKA_PAK2_ST	Q53QZ3	ARHGAP15	Q13177	PAK2	S292	K285T	285	Missense	distal	-7	no	18.434	19.144	EPSD;PhosphoSitePlus	GDSC	14.606	Up-regulation
STE_STE20_PAKA_PAK2_ST	Q53QZ3	ARHGAP15	Q13177	PAK2	S292	N291H	291	Missense	proximal	-1	no	18.434	18.094	EPSD;PhosphoSitePlus	GDSC	14.606	Down-regulation
STE_STE20_PAKA_PAK2_ST	Q53QZ3	ARHGAP15	Q13177	PAK2	S292	E288G	288	Missense	distal	-4	no	18.434	20.017	EPSD;PhosphoSitePlus	GDSC;CCLE	14.606	Up-regulation
STE_STE20_PAKA_PAK2_ST	Q13177	PAK2	Q13177	PAK2	S19	A13S	13	Missense	distal	-6	no	28.410	25.898	EPSD	GDSC;CCLE	14.606	Down-regulation
STE_STE20_PAKA_PAK2_ST	Q13177	PAK2	Q13177	PAK2	S20	A13S	13	Missense	distal	-7	no	32.118	31.877	EPSD	GDSC;CCLE	14.606	Down-regulation
STE_STE20_PAKA_PAK2_ST	Q13177	PAK2	Q13177	PAK2	S401	Y408C	408	Missense	distal	7	no	14.649	15.575	EPSD	GDSC;CCLE	14.606	Up-regulation
STE_STE20_PAKA_PAK2_ST	Q13177	PAK2	Q13177	PAK2	T402	Y408C	408	Missense	distal	6	no	35.000	35.076	PhosphoSitePlus	GDSC;CCLE	14.606	Up-regulation
STE_STE20_PAKA_PAK2_ST	Q13177	PAK2	Q13177	PAK2	S507	S508I	508	Missense	proximal	1	no	22.830	21.828	EPSD	GDSC;CCLE	14.606	Down-regulation
STE_STE20_PAKA_PAK2_ST	P05412	JUN	Q13177	PAK2	T89	H87R	87	Missense	proximal	-2	no	33.388	38.345	EPSD;PhosphoSitePlus	GDSC;CCLE	14.606	Up-regulation
STE_STE20_PAKA_PAK2_ST	P05412	JUN	Q13177	PAK2	T93	H87R	87	Missense	distal	-6	no	24.978	25.221	EPSD;PhosphoSitePlus	GDSC;CCLE	14.606	Up-regulation
STE_STE20_PAKA_PAK2_ST	P05412	JUN	Q13177	PAK2	T286	Q290*	290	Missense	distal	4	no	28.963	30.879	EPSD;PhosphoSitePlus	GDSC	14.606	Up-regulation
STE_STE20_PAKA_PAK2_ST	P05412	JUN	Q13177	PAK2	T286	E282*	282	Missense	distal	-4	no	28.963	29.676	EPSD;PhosphoSitePlus	GDSC	14.606	Up-regulation
STE_STE20_PAKA_PAK2_ST	P49023	PXN	Q13177	PAK2	S130	P129L	129	Missense	proximal	-1	no	8.156	16.640	EPSD	GDSC	14.606	Gain
STE_STE20_PAKA_PAK2_ST	P49023	PXN	Q13177	PAK2	S135	P129L	129	Missense	distal	-6	no	23.779	23.421	EPSD	GDSC	14.606	Down-regulation
STE_STE20_PAKA_PAK2_ST	P49023	PXN	Q13177	PAK2	S274	G280R	280	Missense	distal	6	no	31.516	30.391	EPSD;PhosphoSitePlus	GDSC	14.606	Down-regulation
STE_STE20_PAKA_PAK2_ST	P49023	PXN	Q13177	PAK2	S302	R301G	301	Missense	proximal	-1	no	17.695	13.563	EPSD	GDSC	14.606	Loss
STE_STE20_PAKA_PAK2_ST	P49023	PXN	Q13177	PAK2	S302	S302G	302	Missense	central	0	yes	17.695	0.000	EPSD	GDSC	14.606	Loss
STE_STE20_PAKA_PAK2_ST	P49023	PXN	Q13177	PAK2	S302	G305R	305	Missense	distal	3	no	17.695	16.337	EPSD	GDSC	14.606	Down-regulation
STE_STE20_PAKA_PAK2_ST	P49023	PXN	Q13177	PAK2	S303	R301G	301	Missense	proximal	-2	no	32.352	13.023	EPSD	GDSC	14.606	Loss
STE_STE20_PAKA_PAK2_ST	P49023	PXN	Q13177	PAK2	S303	S302G	302	Missense	proximal	-1	no	32.352	29.074	EPSD	GDSC	14.606	Down-regulation
STE_STE20_PAKA_PAK2_ST	P49023	PXN	Q13177	PAK2	S303	G305R	305	Missense	proximal	2	no	32.352	32.423	EPSD	GDSC	14.606	Up-regulation
STE_STE20_PAKA_PAK2_ST	P49023	PXN	Q13177	PAK2	S320	S321N	321	Missense	proximal	1	no	19.499	17.444	EPSD	GDSC;CCLE	14.606	Down-regulation
STE_STE20_PAKA_PAK2_ST	P49023	PXN	Q13177	PAK2	S332	G331R	331	Missense	proximal	-1	no	24.417	28.549	EPSD	GDSC	14.606	Up-regulation
STE_STE20_PAKA_PAK2_ST	Q05682	CALD1	Q13177	PAK2	T83	E77K	77	Missense	distal	-6	no	20.183	19.437	EPSD	GDSC	14.606	Down-regulation
STE_STE20_PAKA_PAK2_ST	Q05682	CALD1	Q13177	PAK2	S480	D483V	483	Missense	distal	3	no	20.328	17.988	EPSD	GDSC;CCLE	14.606	Down-regulation
STE_STE20_PAKA_PAK2_ST	Q05682	CALD1	Q13177	PAK2	S480	K475R	475	Missense	distal	-5	no	20.328	18.721	EPSD	GDSC	14.606	Down-regulation
STE_STE20_PAKA_PAK2_ST	Q05682	CALD1	Q13177	PAK2	S744	S743F	743	Missense	proximal	-1	no	29.070	23.440	PhosphoSitePlus;EPSD	GDSC	14.606	Down-regulation
STE_STE20_PAKA_PAK2_ST	Q05682	CALD1	Q13177	PAK2	S744	K739N	739	Missense	distal	-5	no	29.070	28.197	PhosphoSitePlus;EPSD	GDSC;CCLE	14.606	Down-regulation
STE_STE20_PAKA_PAK2_ST	Q16659	MAPK6	Q13177	PAK2	S450	R449S	449	Missense	proximal	-1	no	20.229	19.376	EPSD	GDSC;CCLE	14.606	Down-regulation
STE_STE20_PAKA_PAK2_ST	Q16659	MAPK6	Q13177	PAK2	S451	R449S	449	Missense	proximal	-2	no	25.098	1.374	EPSD	GDSC;CCLE	14.606	Loss
STE_STE20_PAKA_PAK2_ST	Q16659	MAPK6	Q13177	PAK2	S704	M702V	702	Missense	proximal	-2	no	22.003	18.043	EPSD	GDSC;CCLE	14.606	Down-regulation
STE_STE20_PAKA_PAK2_ST	Q16659	MAPK6	Q13177	PAK2	S705	M702V	702	Missense	distal	-3	no	17.680	4.650	EPSD	GDSC;CCLE	14.606	Loss
STE_STE20_PAKA_PAK2_ST	P00519	ABL1	Q13177	PAK2	S663	A666D	666	Missense	distal	3	no	14.971	18.090	EPSD	GDSC	14.606	Up-regulation
STE_STE20_PAKA_PAK2_ST	P35240	NF2	Q13177	PAK2	T251	N248S	248	Missense	distal	-3	no	23.380	27.111	EPSD	GDSC;CCLE	14.606	Up-regulation
STE_STE20_PAKA_PAK2_ST	P35240	NF2	Q13177	PAK2	S255	R262*	262	Missense	distal	7	no	24.681	26.213	EPSD	GDSC	14.606	Up-regulation
STE_STE20_PAKA_PAK2_ST	P35240	NF2	Q13177	PAK2	S255	N248S	248	Missense	distal	-7	no	24.681	22.203	EPSD	GDSC;CCLE	14.606	Down-regulation
STE_STE20_PAKA_PAK2_ST	P35240	NF2	Q13177	PAK2	S265	R262*	262	Missense	distal	-3	no	26.682	10.358	EPSD	GDSC	14.606	Loss
STE_STE20_PAKA_PAK2_ST	P35240	NF2	Q13177	PAK2	S265	I264V	264	Missense	proximal	-1	no	26.682	16.619	EPSD	GDSC;CCLE	14.606	Down-regulation
STE_STE20_PAKA_PAK2_ST	Q04637	EIF4G1	Q13177	PAK2	S314	A321V	321	Missense	distal	7	no	19.342	22.682	EPSD	GDSC	14.606	Up-regulation
STE_STE20_PAKA_PAK2_ST	Q04637	EIF4G1	Q13177	PAK2	S314	R312C	312	Missense	proximal	-2	no	19.342	7.741	EPSD	GDSC	14.606	Loss
STE_STE20_PAKA_PAK2_ST	Q04637	EIF4G1	Q13177	PAK2	S332	P334Q	334	Missense	proximal	2	no	11.768	15.035	EPSD	GDSC	14.606	Gain
STE_STE20_PAKA_PAK2_ST	Q04637	EIF4G1	Q13177	PAK2	S895	R893Q	893	Missense	proximal	-2	no	31.597	18.688	PhosphoSitePlus	GDSC;CCLE	14.606	Down-regulation
STE_STE20_PAKA_PAK2_ST	Q04637	EIF4G1	Q13177	PAK2	S895	A891T	891	Missense	distal	-4	no	31.597	32.027	PhosphoSitePlus	GDSC;CCLE	14.606	Up-regulation
STE_STE20_PAKA_PAK2_ST	Q04637	EIF4G1	Q13177	PAK2	T1132	T1132I	1132	Missense	central	0	yes	15.815	0.000	EPSD	GDSC;CCLE	14.606	Loss
STE_STE20_PAKA_PAK2_ST	Q70Z35	PREX2	Q13177	PAK2	S1065	R1062H	1062	Missense	distal	-3	no	23.060	8.217	EPSD	GDSC;CCLE	14.606	Loss
STE_STE20_PAKA_PAK2_ST	Q70Z35	PREX2	Q13177	PAK2	S1065	R1062L	1062	Missense	distal	-3	no	23.060	13.802	EPSD	GDSC;CCLE	14.606	Loss
STE_STE20_PAKA_PAK2_ST	Q8IYU2	HACE1	Q13177	PAK2	S385	N381K	381	Missense	distal	-4	no	35.489	33.491	PhosphoSitePlus	GDSC;CCLE	14.606	Down-regulation
CMGC_MAPK_ERK7_MAPK15_ST	Q8TD08	MAPK15	Q8TD08	MAPK15	T352	E345V	345	Missense	distal	-7	no	9.993	9.721	EPSD;PhosphoSitePlus	GDSC;CCLE	5.395	Down-regulation
CMGC_MAPK_ERK7_MAPK15_ST	Q8TD08	MAPK15	Q8TD08	MAPK15	T352	G357A	357	Missense	distal	5	no	9.993	9.291	EPSD;PhosphoSitePlus	GDSC;CCLE	5.395	Down-regulation
CMGC_MAPK_ERK7_MAPK15_ST	Q8TD08	MAPK15	Q8TD08	MAPK15	S362	G357A	357	Missense	distal	-5	no	9.448	9.672	EPSD;PhosphoSitePlus	GDSC;CCLE	5.395	Up-regulation
CMGC_MAPK_ERK7_MAPK15_ST	Q8TD08	MAPK15	Q8TD08	MAPK15	S379	P375L	375	Missense	distal	-4	no	10.779	10.832	EPSD;PhosphoSitePlus	GDSC;CCLE	5.395	Up-regulation
CMGC_MAPK_ERK7_MAPK15_ST	Q8TD08	MAPK15	Q8TD08	MAPK15	T381	P375L	375	Missense	distal	-6	no	10.411	10.576	PhosphoSitePlus;EPSD	GDSC;CCLE	5.395	Up-regulation
CMGC_MAPK_ERK7_MAPK15_ST	Q8TD08	MAPK15	Q8TD08	MAPK15	S442	T440A	440	Missense	proximal	-2	no	4.790	5.440	EPSD	GDSC	5.395	Gain
CMGC_MAPK_ERK7_MAPK15_ST	P25963	NFKBIA	Q8TD08	MAPK15	S283	L277P	277	Missense	distal	-6	no	5.408	5.243	EPSD	GDSC	5.395	Loss
CMGC_MAPK_ERK7_MAPK15_ST	P05412	JUN	Q8TD08	MAPK15	T89	H87R	87	Missense	proximal	-2	no	5.426	5.332	EPSD	GDSC;CCLE	5.395	Loss
TK_Ret_RET_Y	P07949	RET	P07949	RET	Y687	S688Y	688	Missense	proximal	1	no	50.930	48.087	EPSD;PhosphoSitePlus	GDSC;CCLE	28.094	Down-regulation
TK_Ret_RET_Y	P07949	RET	P07949	RET	Y806	E805*	805	Missense	proximal	-1	no	31.198	31.297	EPSD;PhosphoSitePlus	GDSC	28.094	Up-regulation
TK_Ret_RET_Y	P07949	RET	P07949	RET	Y809	E805*	805	Missense	distal	-4	no	39.481	34.381	EPSD;PhosphoSitePlus	GDSC	28.094	Down-regulation
TK_Ret_RET_Y	P07949	RET	P07949	RET	Y826	G828R	828	Missense	proximal	2	no	41.269	41.468	PhosphoSitePlus;EPSD	GDSC;CCLE	28.094	Up-regulation
TK_Ret_RET_Y	P07949	RET	P07949	RET	Y1015	D1017E	1017	Missense	proximal	2	no	48.606	48.508	EPSD;PhosphoSitePlus	GDSC;CCLE	28.094	Down-regulation
TK_Ret_RET_Y	P07949	RET	P07949	RET	Y1090	N1084S	1084	Missense	distal	-6	no	37.417	37.458	EPSD;PhosphoSitePlus	GDSC;CCLE	28.094	Up-regulation
TK_Ret_RET_Y	P07949	RET	P07949	RET	Y1090	P1091A	1091	Missense	proximal	1	no	37.417	38.271	EPSD;PhosphoSitePlus	GDSC;CCLE	28.094	Up-regulation
TK_Ret_RET_Y	P07949	RET	P07949	RET	Y1096	P1091A	1091	Missense	distal	-5	no	59.110	59.240	EPSD;PhosphoSitePlus	GDSC;CCLE	28.094	Up-regulation
TK_Ret_RET_Y	O15530	PDPK1	P07949	RET	Y373	N378S	378	Missense	distal	5	no	29.217	29.540	EPSD	GDSC;CCLE	28.094	Up-regulation
TK_Ret_RET_Y	P19174	PLCG1	P07949	RET	Y669	E667G	667	Missense	proximal	-2	no	39.231	35.587	EPSD	GDSC	28.094	Down-regulation
TK_Ret_RET_Y	P19174	PLCG1	P07949	RET	Y783	E785K	785	Missense	proximal	2	no	51.128	51.194	PhosphoSitePlus	GDSC;CCLE	28.094	Up-regulation
TK_Ret_RET_Y	Q8N4X5	AFAP1L2	P07949	RET	Y537	R535*	535	Missense	proximal	-2	no	36.315	32.857	EPSD	GDSC	28.094	Down-regulation
TK_Ret_RET_Y	P45984	MAPK9	P07949	RET	Y185	V186L	186	Missense	proximal	1	no	56.127	55.413	PhosphoSitePlus	GDSC;CCLE	28.094	Down-regulation
TK_Ret_RET_Y	P45984	MAPK9	P07949	RET	Y185	T188S	188	Missense	distal	3	no	56.127	56.554	PhosphoSitePlus	GDSC;CCLE	28.094	Up-regulation
TK_Ret_RET_Y	P28482	MAPK1	P07949	RET	Y187	T185A	185	Missense	proximal	-2	no	57.218	57.796	PhosphoSitePlus	GDSC;CCLE	28.094	Up-regulation
TK_Ret_RET_Y	P28482	MAPK1	P07949	RET	Y205	I211M	211	Missense	distal	6	no	35.107	36.354	EPSD	GDSC;CCLE	28.094	Up-regulation
TK_Ret_RET_Y	P27361	MAPK3	P07949	RET	Y204	E203D	203	Missense	proximal	-1	no	57.849	57.822	PhosphoSitePlus	GDSC;CCLE	28.094	Down-regulation
TK_Ret_RET_Y	P27361	MAPK3	P07949	RET	Y204	H197D	197	Missense	distal	-7	no	57.849	60.286	PhosphoSitePlus	GDSC;CCLE	28.094	Up-regulation
TK_Ret_RET_Y	P27361	MAPK3	P07949	RET	Y222	I228V	228	Missense	distal	6	no	34.972	36.040	EPSD	GDSC	28.094	Up-regulation
TK_Ret_RET_Y	Q16539	MAPK14	P07949	RET	Y258	E253A	253	Missense	distal	-5	no	32.577	32.964	EPSD	GDSC;CCLE	28.094	Up-regulation
AGC_Akt_AKT1_ST	P19634	SLC9A1	P31749	AKT1	S648	R647L	647	Missense	proximal	-1	no	15.140	15.101	PhosphoSitePlus;EPSD	GDSC;CCLE	7.780	Down-regulation
AGC_Akt_AKT1_ST	P19634	SLC9A1	P31749	AKT1	S703	A707V	707	Missense	distal	4	no	15.032	15.087	EPSD;PhosphoSitePlus	GDSC;CCLE	7.780	Up-regulation
AGC_Akt_AKT1_ST	Q06187	BTK	P31749	AKT1	T495	L499I	499	Missense	distal	4	no	14.279	14.352	PhosphoSitePlus;EPSD	GDSC	7.780	Up-regulation
AGC_Akt_AKT1_ST	Q06187	BTK	P31749	AKT1	T495	M489I	489	Missense	distal	-6	no	14.279	14.221	PhosphoSitePlus;EPSD	GDSC;CCLE	7.780	Down-regulation
AGC_Akt_AKT1_ST	Q9NR28	DIABLO	P31749	AKT1	S67	A60V	60	Missense	distal	-7	no	8.220	8.092	PhosphoSitePlus	GDSC	7.780	Down-regulation
AGC_Akt_AKT1_ST	Q9NR28	DIABLO	P31749	AKT1	S67	S70G	70	Missense	distal	3	no	8.220	8.130	PhosphoSitePlus	GDSC;CCLE	7.780	Down-regulation
AGC_Akt_AKT1_ST	Q9NR28	DIABLO	P31749	AKT1	S69	S70G	70	Missense	proximal	1	no	7.840	7.535	EPSD	GDSC;CCLE	7.780	Loss
AGC_Akt_AKT1_ST	Q9NR28	DIABLO	P31749	AKT1	T220	G224R	224	Missense	distal	4	no	10.595	10.432	EPSD	GDSC	7.780	Down-regulation
AGC_Akt_AKT1_ST	Q9NR28	DIABLO	P31749	AKT1	S230	G224R	224	Missense	distal	-6	no	13.712	13.826	EPSD	GDSC	7.780	Up-regulation
AGC_Akt_AKT1_ST	O43521	BCL2L11	P31749	AKT1	S90	G95E	95	Missense	distal	5	no	8.219	8.249	EPSD	GDSC;CCLE	7.780	Up-regulation
AGC_Akt_AKT1_ST	O43521	BCL2L11	P31749	AKT1	S94	G95E	95	Missense	proximal	1	no	13.394	13.603	EPSD	GDSC;CCLE	7.780	Up-regulation
AGC_Akt_AKT1_ST	P29474	NOS3	P31749	AKT1	S102	V104I	104	Missense	proximal	2	no	10.188	10.070	EPSD	GDSC;CCLE	7.780	Down-regulation
AGC_Akt_AKT1_ST	P29474	NOS3	P31749	AKT1	S633	R627Q	627	Missense	distal	-6	no	17.774	17.690	EPSD	GDSC;CCLE	7.780	Down-regulation
AGC_Akt_AKT1_ST	P29474	NOS3	P31749	AKT1	S633	R628Q	628	Missense	distal	-5	no	17.774	13.547	EPSD	GDSC	7.780	Down-regulation
AGC_Akt_AKT1_ST	P29474	NOS3	P31749	AKT1	S634	R627Q	627	Missense	distal	-7	no	10.558	10.364	EPSD	GDSC;CCLE	7.780	Down-regulation
AGC_Akt_AKT1_ST	P29474	NOS3	P31749	AKT1	S634	R628Q	628	Missense	distal	-6	no	10.558	10.474	EPSD	GDSC	7.780	Down-regulation
AGC_Akt_AKT1_ST	P29474	NOS3	P31749	AKT1	S634	A641S	641	Missense	distal	7	no	10.558	10.609	EPSD	GDSC;CCLE	7.780	Up-regulation
AGC_Akt_AKT1_ST	P29474	NOS3	P31749	AKT1	T1175	R1174C	1174	Missense	proximal	-1	no	11.266	11.196	EPSD	GDSC;CCLE	7.780	Down-regulation
AGC_Akt_AKT1_ST	P29474	NOS3	P31749	AKT1	T1175	R1172C	1172	Missense	distal	-3	no	11.266	5.093	EPSD	GDSC;CCLE	7.780	Loss
AGC_Akt_AKT1_ST	P29474	NOS3	P31749	AKT1	T1175	T1170K	1170	Missense	distal	-5	no	11.266	12.599	EPSD	GDSC	7.780	Up-regulation
AGC_Akt_AKT1_ST	P29474	NOS3	P31749	AKT1	T1175	I1173T	1173	Missense	proximal	-2	no	11.266	12.441	EPSD	GDSC;CCLE	7.780	Up-regulation
AGC_Akt_AKT1_ST	P29474	NOS3	P31749	AKT1	S1177	R1174C	1174	Missense	distal	-3	no	17.081	10.908	EPSD;PhosphoSitePlus	GDSC;CCLE	7.780	Down-regulation
AGC_Akt_AKT1_ST	P29474	NOS3	P31749	AKT1	S1177	R1172C	1172	Missense	distal	-5	no	17.081	13.004	EPSD;PhosphoSitePlus	GDSC;CCLE	7.780	Down-regulation
AGC_Akt_AKT1_ST	P29474	NOS3	P31749	AKT1	S1177	T1175S	1175	Missense	proximal	-2	no	17.081	17.148	EPSD;PhosphoSitePlus	GDSC;CCLE	7.780	Up-regulation
AGC_Akt_AKT1_ST	P29474	NOS3	P31749	AKT1	S1177	T1170K	1170	Missense	distal	-7	no	17.081	17.074	EPSD;PhosphoSitePlus	GDSC	7.780	Down-regulation
AGC_Akt_AKT1_ST	P29474	NOS3	P31749	AKT1	S1177	I1173T	1173	Missense	distal	-4	no	17.081	18.519	EPSD;PhosphoSitePlus	GDSC;CCLE	7.780	Up-regulation
AGC_Akt_AKT1_ST	P29474	NOS3	P31749	AKT1	S1179	R1174C	1174	Missense	distal	-5	no	11.305	7.228	EPSD	GDSC;CCLE	7.780	Loss
AGC_Akt_AKT1_ST	P29474	NOS3	P31749	AKT1	S1179	R1172C	1172	Missense	distal	-7	no	11.305	10.826	EPSD	GDSC;CCLE	7.780	Down-regulation
AGC_Akt_AKT1_ST	P29474	NOS3	P31749	AKT1	S1179	T1175S	1175	Missense	distal	-4	no	11.305	11.249	EPSD	GDSC;CCLE	7.780	Down-regulation
AGC_Akt_AKT1_ST	P29474	NOS3	P31749	AKT1	S1179	I1173T	1173	Missense	distal	-6	no	11.305	11.456	EPSD	GDSC;CCLE	7.780	Up-regulation
AGC_Akt_AKT1_ST	P19484	TFEB	P31749	AKT1	T308	H301R	301	Missense	distal	-7	no	7.750	8.052	EPSD	GDSC;CCLE	7.780	Gain
AGC_Akt_AKT1_ST	P19484	TFEB	P31749	AKT1	S463	R465W	465	Missense	proximal	2	no	11.685	11.230	EPSD	GDSC;CCLE	7.780	Down-regulation
AGC_Akt_AKT1_ST	P19484	TFEB	P31749	AKT1	S467	R465W	465	Missense	proximal	-2	no	15.178	13.924	PhosphoSitePlus	GDSC;CCLE	7.780	Down-regulation
AGC_Akt_AKT1_ST	P19484	TFEB	P31749	AKT1	S469	R465W	465	Missense	distal	-4	no	11.305	9.756	EPSD	GDSC;CCLE	7.780	Down-regulation
AGC_Akt_AKT1_ST	P31749	AKT1	P31749	AKT1	T72	I75M	75	Missense	distal	3	no	15.377	15.423	PhosphoSitePlus;EPSD	GDSC;CCLE	7.780	Up-regulation
AGC_Akt_AKT1_ST	P31749	AKT1	P31749	AKT1	S473	G478S	478	Missense	distal	5	no	7.952	8.015	EPSD	GDSC;CCLE	7.780	Up-regulation
AGC_Akt_AKT1_ST	P31749	AKT1	P31749	AKT1	S475	G478S	478	Missense	distal	3	no	7.786	7.876	EPSD	GDSC;CCLE	7.780	Up-regulation
AGC_Akt_AKT1_ST	P19174	PLCG1	P31749	AKT1	T932	D934Y	934	Missense	proximal	2	no	7.641	7.867	EPSD	GDSC;CCLE	7.780	Gain
AGC_Akt_AKT1_ST	P19174	PLCG1	P31749	AKT1	T932	A930T	930	Missense	proximal	-2	no	7.641	8.026	EPSD	GDSC;CCLE	7.780	Gain
AGC_Akt_AKT1_ST	P29375	KDM5A	P31749	AKT1	T223	R220C	220	Missense	distal	-3	no	12.552	6.378	EPSD	GDSC;CCLE	7.780	Loss
AGC_Akt_AKT1_ST	P29375	KDM5A	P31749	AKT1	S225	R220C	220	Missense	distal	-5	no	13.181	9.105	EPSD;PhosphoSitePlus	GDSC;CCLE	7.780	Down-regulation
AGC_Akt_AKT1_ST	P29375	KDM5A	P31749	AKT1	T285	Q281K	281	Missense	distal	-4	no	16.140	16.748	EPSD;PhosphoSitePlus	GDSC;CCLE	7.780	Up-regulation
AGC_Akt_AKT1_ST	P29375	KDM5A	P31749	AKT1	S287	Q281K	281	Missense	distal	-6	no	10.380	10.450	PhosphoSitePlus;EPSD	GDSC;CCLE	7.780	Up-regulation
AGC_Akt_AKT1_ST	P29375	KDM5A	P31749	AKT1	S1067	T1069A	1069	Missense	proximal	2	no	8.000	7.699	EPSD	GDSC;CCLE	7.780	Loss
AGC_Akt_AKT1_ST	P29375	KDM5A	P31749	AKT1	S1410	S1408N	1408	Missense	proximal	-2	no	8.778	8.092	EPSD	GDSC	7.780	Down-regulation
AGC_Akt_AKT1_ST	P29375	KDM5A	P31749	AKT1	S1410	G1412C	1412	Missense	proximal	2	no	8.778	8.286	EPSD	GDSC	7.780	Down-regulation
AGC_Akt_AKT1_ST	P29375	KDM5A	P31749	AKT1	S1410	R1417M	1417	Missense	distal	7	no	8.778	8.712	EPSD	GDSC;CCLE	7.780	Down-regulation
AGC_Akt_AKT1_ST	P29375	KDM5A	P31749	AKT1	S1666	G1663R	1663	Missense	distal	-3	no	7.019	13.775	EPSD	GDSC;CCLE	7.780	Gain
AGC_Akt_AKT1_ST	P29375	KDM5A	P31749	AKT1	S1678	I1676L	1676	Missense	proximal	-2	no	7.681	8.065	EPSD	GDSC	7.780	Gain
AGC_Akt_AKT1_ST	P49815	TSC2	P31749	AKT1	S981	R988C	988	Missense	distal	7	no	14.283	14.153	EPSD;PhosphoSitePlus	GDSC;CCLE	7.780	Down-regulation
AGC_Akt_AKT1_ST	P49815	TSC2	P31749	AKT1	S983	R988C	988	Missense	distal	5	no	9.011	8.884	EPSD	GDSC;CCLE	7.780	Down-regulation
AGC_Akt_AKT1_ST	P49815	TSC2	P31749	AKT1	T993	R988C	988	Missense	distal	-5	no	12.911	8.834	EPSD	GDSC;CCLE	7.780	Down-regulation
AGC_Akt_AKT1_ST	P49815	TSC2	P31749	AKT1	S1045	P1042R	1042	Missense	distal	-3	no	5.300	11.940	EPSD	GDSC;CCLE	7.780	Gain
AGC_Akt_AKT1_ST	P49815	TSC2	P31749	AKT1	T1271	L1266M	1266	Missense	distal	-5	no	11.438	11.042	EPSD	GDSC;CCLE	7.780	Down-regulation
AGC_Akt_AKT1_ST	P49815	TSC2	P31749	AKT1	S1418	S1411R	1411	Missense	distal	-7	no	8.245	8.301	EPSD	GDSC;CCLE	7.780	Up-regulation
AGC_Akt_AKT1_ST	Q15633	TARBP2	P31749	AKT1	S283	C282Y	282	Missense	proximal	-1	no	10.998	11.032	PhosphoSitePlus	GDSC	7.780	Up-regulation
AGC_Akt_AKT1_ST	Q15633	TARBP2	P31749	AKT1	S283	S281R	281	Missense	proximal	-2	no	10.998	10.809	PhosphoSitePlus	GDSC	7.780	Down-regulation
AGC_Akt_AKT1_ST	P14618	PKM	P31749	AKT1	S249	S249F	249	Missense	central	0	yes	11.640	0.000	EPSD	GDSC;CCLE	7.780	Loss
AGC_Akt_AKT1_ST	P14618	PKM	P31749	AKT1	S249	D250V	250	Missense	proximal	1	no	11.640	11.852	EPSD	GDSC	7.780	Up-regulation
AGC_Akt_AKT1_ST	P02545	LMNA	P31749	AKT1	S75	E82V	82	Missense	distal	7	no	11.162	11.141	EPSD	GDSC	7.780	Down-regulation
AGC_Akt_AKT1_ST	P02545	LMNA	P31749	AKT1	S404	G411C	411	Missense	distal	7	no	14.842	14.793	PhosphoSitePlus;EPSD	GDSC;CCLE	7.780	Down-regulation
AGC_Akt_AKT1_ST	P02545	LMNA	P31749	AKT1	S404	S403P	403	Missense	proximal	-1	no	14.842	14.813	PhosphoSitePlus;EPSD	GDSC;CCLE	7.780	Down-regulation
AGC_Akt_AKT1_ST	P02545	LMNA	P31749	AKT1	S406	G411C	411	Missense	distal	5	no	7.840	7.784	EPSD	GDSC;CCLE	7.780	Down-regulation
AGC_Akt_AKT1_ST	P02545	LMNA	P31749	AKT1	S406	S403P	403	Missense	distal	-3	no	7.840	8.976	EPSD	GDSC;CCLE	7.780	Up-regulation
AGC_Akt_AKT1_ST	P02545	LMNA	P31749	AKT1	S657	S662I	662	Missense	distal	5	no	12.872	12.775	EPSD	GDSC;CCLE	7.780	Down-regulation
AGC_Akt_AKT1_ST	P02545	LMNA	P31749	AKT1	S657	N660I	660	Missense	distal	3	no	12.872	12.797	EPSD	GDSC;CCLE	7.780	Down-regulation
AGC_Akt_AKT1_ST	P38398	BRCA1	P31749	AKT1	T509	L502*	502	Missense	distal	-7	no	15.352	14.864	PhosphoSitePlus;EPSD	GDSC	7.780	Down-regulation
AGC_Akt_AKT1_ST	P38398	BRCA1	P31749	AKT1	S956	L954I	954	Missense	proximal	-2	no	8.809	8.424	EPSD	GDSC;CCLE	7.780	Down-regulation
AGC_Akt_AKT1_ST	P38398	BRCA1	P31749	AKT1	S956	G949C	949	Missense	distal	-7	no	8.809	8.572	EPSD	GDSC;CCLE	7.780	Down-regulation
AGC_Akt_AKT1_ST	P38398	BRCA1	P31749	AKT1	S1516	Q1518H	1518	Missense	proximal	2	no	8.392	8.148	EPSD	GDSC	7.780	Down-regulation
AGC_Akt_AKT1_ST	Q16584	MAP3K11	P31749	AKT1	S555	R561Q	561	Missense	distal	6	no	8.655	8.585	EPSD	GDSC	7.780	Down-regulation
AGC_Akt_AKT1_ST	Q16584	MAP3K11	P31749	AKT1	S674	T676R	676	Missense	proximal	2	no	16.907	16.809	PhosphoSitePlus	GDSC	7.780	Down-regulation
AGC_Akt_AKT1_ST	Q16584	MAP3K11	P31749	AKT1	S674	P681S	681	Missense	distal	7	no	16.907	16.965	PhosphoSitePlus	GDSC	7.780	Up-regulation
AGC_Akt_AKT1_ST	Q16584	MAP3K11	P31749	AKT1	S780	R787W	787	Missense	distal	7	no	8.768	8.670	EPSD	GDSC	7.780	Down-regulation
AGC_Akt_AKT1_ST	P55211	CASP9	P31749	AKT1	T125	P123L	123	Missense	proximal	-2	no	10.550	10.517	EPSD	GDSC	7.780	Down-regulation
AGC_Akt_AKT1_ST	P55211	CASP9	P31749	AKT1	T181	G176R	176	Missense	distal	-5	no	11.872	15.937	EPSD	GDSC;CCLE	7.780	Up-regulation
AGC_Akt_AKT1_ST	P55211	CASP9	P31749	AKT1	S183	G176R	176	Missense	distal	-7	no	17.682	17.924	EPSD	GDSC;CCLE	7.780	Up-regulation
AGC_Akt_AKT1_ST	O60343	TBC1D4	P31749	AKT1	S133	H131R	131	Missense	proximal	-2	no	7.243	8.104	EPSD	GDSC;CCLE	7.780	Gain
AGC_Akt_AKT1_ST	O60343	TBC1D4	P31749	AKT1	S318	Q323P	323	Missense	distal	5	no	15.833	15.823	PhosphoSitePlus;EPSD	GDSC;CCLE	7.780	Down-regulation
AGC_Akt_AKT1_ST	O60343	TBC1D4	P31749	AKT1	S330	R337W	337	Missense	distal	7	no	10.553	10.455	EPSD	GDSC;CCLE	7.780	Down-regulation
AGC_Akt_AKT1_ST	O60343	TBC1D4	P31749	AKT1	S330	R336*	336	Missense	distal	6	no	10.553	10.264	EPSD	GDSC	7.780	Down-regulation
AGC_Akt_AKT1_ST	O60343	TBC1D4	P31749	AKT1	S330	Q323P	323	Missense	distal	-7	no	10.553	10.498	EPSD	GDSC;CCLE	7.780	Down-regulation
AGC_Akt_AKT1_ST	O60343	TBC1D4	P31749	AKT1	S341	R337W	337	Missense	distal	-4	no	16.535	14.986	EPSD;PhosphoSitePlus	GDSC;CCLE	7.780	Down-regulation
AGC_Akt_AKT1_ST	O60343	TBC1D4	P31749	AKT1	S341	R336*	336	Missense	distal	-5	no	16.535	5.775	EPSD;PhosphoSitePlus	GDSC	7.780	Loss
AGC_Akt_AKT1_ST	O60343	TBC1D4	P31749	AKT1	T568	K564N	564	Missense	distal	-4	no	12.685	12.046	EPSD;PhosphoSitePlus	GDSC;CCLE	7.780	Down-regulation
AGC_Akt_AKT1_ST	O60343	TBC1D4	P31749	AKT1	T568	K564R	564	Missense	distal	-4	no	12.685	12.698	EPSD;PhosphoSitePlus	GDSC	7.780	Up-regulation
AGC_Akt_AKT1_ST	O60343	TBC1D4	P31749	AKT1	S569	K564R	564	Missense	distal	-5	no	5.721	8.118	EPSD	GDSC	7.780	Gain
AGC_Akt_AKT1_ST	O60343	TBC1D4	P31749	AKT1	S570	K564N	564	Missense	distal	-6	no	9.973	9.906	EPSD;PhosphoSitePlus	GDSC;CCLE	7.780	Down-regulation
AGC_Akt_AKT1_ST	O60343	TBC1D4	P31749	AKT1	S570	K564R	564	Missense	distal	-6	no	9.973	9.987	EPSD;PhosphoSitePlus	GDSC	7.780	Up-regulation
AGC_Akt_AKT1_ST	O60343	TBC1D4	P31749	AKT1	S771	R769Q	769	Missense	proximal	-2	no	11.807	11.295	EPSD	GDSC;CCLE	7.780	Down-regulation
AGC_Akt_AKT1_ST	O60343	TBC1D4	P31749	AKT1	S771	R769W	769	Missense	proximal	-2	no	11.807	10.553	EPSD	GDSC	7.780	Down-regulation
AGC_Akt_AKT1_ST	O60343	TBC1D4	P31749	AKT1	S1050	M1048I	1048	Missense	proximal	-2	no	10.165	9.764	EPSD	GDSC;CCLE	7.780	Down-regulation
AGC_Akt_AKT1_ST	O60343	TBC1D4	P31749	AKT1	S1207	S1207N	1207	Missense	central	0	yes	10.377	0.000	EPSD	GDSC;CCLE	7.780	Loss
AGC_Akt_AKT1_ST	Q2PPJ7	RALGAPA2	P31749	AKT1	S469	T463I	463	Missense	distal	-6	no	8.075	7.924	EPSD	GDSC;CCLE	7.780	Down-regulation
AGC_Akt_AKT1_ST	Q2PPJ7	RALGAPA2	P31749	AKT1	S696	V691L	691	Missense	distal	-5	no	11.600	11.788	EPSD	GDSC;CCLE	7.780	Up-regulation
AGC_Akt_AKT1_ST	Q2PPJ7	RALGAPA2	P31749	AKT1	S698	V691L	691	Missense	distal	-7	no	10.338	10.382	EPSD	GDSC;CCLE	7.780	Up-regulation
AGC_Akt_AKT1_ST	Q2PPJ7	RALGAPA2	P31749	AKT1	S766	T767P	767	Missense	proximal	1	no	11.428	11.080	EPSD	GDSC	7.780	Down-regulation
AGC_Akt_AKT1_ST	Q2PPJ7	RALGAPA2	P31749	AKT1	S768	T767P	767	Missense	proximal	-1	no	8.956	8.921	EPSD	GDSC	7.780	Down-regulation
AGC_Akt_AKT1_ST	Q2PPJ7	RALGAPA2	P31749	AKT1	S820	A823T	823	Missense	distal	3	no	9.942	9.999	EPSD	GDSC;CCLE	7.780	Up-regulation
AGC_Akt_AKT1_ST	Q2PPJ7	RALGAPA2	P31749	AKT1	S821	A823T	823	Missense	proximal	2	no	11.519	11.820	EPSD	GDSC;CCLE	7.780	Up-regulation
AGC_Akt_AKT1_ST	Q2PPJ7	RALGAPA2	P31749	AKT1	T1646	R1644C	1644	Missense	proximal	-2	no	8.788	7.324	EPSD	GDSC	7.780	Loss
AGC_Akt_AKT1_ST	Q3V6T2	CCDC88A	P31749	AKT1	S913	V912M	912	Missense	proximal	-1	no	8.703	8.709	EPSD	GDSC;CCLE	7.780	Up-regulation
AGC_Akt_AKT1_ST	Q3V6T2	CCDC88A	P31749	AKT1	S1151	E1147Q	1147	Missense	distal	-4	no	8.348	8.325	EPSD	GDSC	7.780	Down-regulation
AGC_Akt_AKT1_ST	P42345	MTOR	P31749	AKT1	S1166	R1161*	1161	Missense	distal	-5	no	8.003	-2.757	EPSD	GDSC	7.780	Loss
AGC_Akt_AKT1_ST	P42345	MTOR	P31749	AKT1	S1893	R1896*	1896	Missense	distal	3	no	12.435	12.260	EPSD	GDSC	7.780	Down-regulation
AGC_Akt_AKT1_ST	P42345	MTOR	P31749	AKT1	S1893	L1894V	1894	Missense	proximal	1	no	12.435	12.336	EPSD	GDSC;CCLE	7.780	Down-regulation
AGC_Akt_AKT1_ST	P42345	MTOR	P31749	AKT1	T1948	P1951S	1951	Missense	distal	3	no	10.263	10.344	EPSD	GDSC	7.780	Up-regulation
AGC_Akt_AKT1_ST	P42345	MTOR	P31749	AKT1	T2473	P2466S	2466	Missense	distal	-7	no	8.095	8.289	EPSD	GDSC;CCLE	7.780	Up-regulation
AGC_Akt_AKT1_ST	P42345	MTOR	P31749	AKT1	S2514	T2509A	2509	Missense	distal	-5	no	10.472	10.347	EPSD	GDSC;CCLE	7.780	Down-regulation
AGC_Akt_AKT1_ST	P35232	PHB	P31749	AKT1	S151	V150G	150	Missense	proximal	-1	no	11.967	11.972	EPSD	GDSC;CCLE	7.780	Up-regulation
AGC_Akt_AKT1_ST	Q13045	FLII	P31749	AKT1	T818	A817T	817	Missense	proximal	-1	no	14.407	14.434	EPSD	GDSC	7.780	Up-regulation
AGC_Akt_AKT1_ST	Q13045	FLII	P31749	AKT1	S822	A817T	817	Missense	distal	-5	no	7.666	7.791	EPSD	GDSC	7.780	Gain
AGC_Akt_AKT1_ST	Q9UGI0	ZRANB1	P31749	AKT1	S209	C207S	207	Missense	proximal	-2	no	6.523	8.175	EPSD	GDSC;CCLE	7.780	Gain
AGC_Akt_AKT1_ST	Q99683	MAP3K5	P31749	AKT1	S83	S83C	83	Missense	central	0	yes	15.754	0.000	PhosphoSitePlus	GDSC;CCLE	7.780	Loss
AGC_Akt_AKT1_ST	Q99683	MAP3K5	P31749	AKT1	S763	G760R	760	Missense	distal	-3	no	4.854	11.610	EPSD	GDSC	7.780	Gain
AGC_Akt_AKT1_ST	Q99683	MAP3K5	P31749	AKT1	T1059	D1063Y	1063	Missense	distal	4	no	11.135	11.046	EPSD	GDSC	7.780	Down-regulation
AGC_Akt_AKT1_ST	Q9UN36	NDRG2	P31749	AKT1	S346	R343W	343	Missense	distal	-3	no	13.688	4.747	EPSD	GDSC;CCLE	7.780	Loss
AGC_Akt_AKT1_ST	Q9UN36	NDRG2	P31749	AKT1	S346	Q351*	351	Missense	distal	5	no	13.688	13.553	EPSD	GDSC	7.780	Down-regulation
AGC_Akt_AKT1_ST	Q9UN36	NDRG2	P31749	AKT1	T348	R343W	343	Missense	distal	-5	no	15.892	10.372	PhosphoSitePlus;EPSD	GDSC;CCLE	7.780	Down-regulation
AGC_Akt_AKT1_ST	Q9UN36	NDRG2	P31749	AKT1	T348	Q351*	351	Missense	distal	3	no	15.892	15.773	PhosphoSitePlus;EPSD	GDSC	7.780	Down-regulation
AGC_Akt_AKT1_ST	Q9UN36	NDRG2	P31749	AKT1	S350	R343W	343	Missense	distal	-7	no	19.104	18.681	EPSD	GDSC;CCLE	7.780	Down-regulation
AGC_Akt_AKT1_ST	Q9UN36	NDRG2	P31749	AKT1	S350	Q351*	351	Missense	proximal	1	no	19.104	18.751	EPSD	GDSC	7.780	Down-regulation
AGC_Akt_AKT1_ST	Q9UN36	NDRG2	P31749	AKT1	S352	Q351*	351	Missense	proximal	-1	no	11.781	11.714	EPSD	GDSC	7.780	Down-regulation
AGC_Akt_AKT1_ST	O95999	BCL10	P31749	AKT1	S227	R232Q	232	Missense	distal	5	no	7.837	7.786	EPSD	GDSC	7.780	Down-regulation
AGC_Akt_AKT1_ST	O95999	BCL10	P31749	AKT1	S227	R228H	228	Missense	proximal	1	no	7.837	7.515	EPSD	GDSC;CCLE	7.780	Loss
AGC_Akt_AKT1_ST	O95999	BCL10	P31749	AKT1	T229	R232Q	232	Missense	distal	3	no	12.071	12.015	EPSD	GDSC	7.780	Down-regulation
AGC_Akt_AKT1_ST	O95999	BCL10	P31749	AKT1	T229	R228H	228	Missense	proximal	-1	no	12.071	12.026	EPSD	GDSC;CCLE	7.780	Down-regulation
AGC_Akt_AKT1_ST	O95999	BCL10	P31749	AKT1	S231	R232Q	232	Missense	proximal	1	no	18.236	17.941	EPSD;PhosphoSitePlus	GDSC	7.780	Down-regulation
AGC_Akt_AKT1_ST	O95999	BCL10	P31749	AKT1	S231	R228H	228	Missense	distal	-3	no	18.236	13.537	EPSD;PhosphoSitePlus	GDSC;CCLE	7.780	Down-regulation
AGC_Akt_AKT1_ST	P35240	NF2	P31749	AKT1	T189	W184R	184	Missense	distal	-5	no	2.847	8.367	EPSD	GDSC;CCLE	7.780	Gain
AGC_Akt_AKT1_ST	P35240	NF2	P31749	AKT1	T230	E231*	231	Missense	proximal	1	no	10.354	9.946	EPSD;PhosphoSitePlus	GDSC	7.780	Down-regulation
AGC_Akt_AKT1_ST	P35240	NF2	P31749	AKT1	S265	R262*	262	Missense	distal	-3	no	9.943	-7.446	EPSD	GDSC	7.780	Loss
AGC_Akt_AKT1_ST	P35240	NF2	P31749	AKT1	S265	I264V	264	Missense	proximal	-1	no	9.943	9.958	EPSD	GDSC;CCLE	7.780	Up-regulation
AGC_Akt_AKT1_ST	P35240	NF2	P31749	AKT1	S267	R262*	262	Missense	distal	-5	no	8.370	-2.390	EPSD	GDSC	7.780	Loss
AGC_Akt_AKT1_ST	P35240	NF2	P31749	AKT1	S267	I264V	264	Missense	distal	-3	no	8.370	8.586	EPSD	GDSC;CCLE	7.780	Up-regulation
AGC_Akt_AKT1_ST	P35240	NF2	P31749	AKT1	S315	Q320*	320	Missense	distal	5	no	11.067	10.933	PhosphoSitePlus;EPSD	GDSC	7.780	Down-regulation
AGC_Akt_AKT1_ST	Q92547	TOPBP1	P31749	AKT1	T292	N295S	295	Missense	distal	3	no	8.427	8.484	EPSD	GDSC;CCLE	7.780	Up-regulation
AGC_Akt_AKT1_ST	Q92547	TOPBP1	P31749	AKT1	T292	P299R	299	Missense	distal	7	no	8.427	8.493	EPSD	GDSC;CCLE	7.780	Up-regulation
AGC_Akt_AKT1_ST	Q92547	TOPBP1	P31749	AKT1	T779	P780S	780	Missense	proximal	1	no	8.056	8.212	EPSD	GDSC;CCLE	7.780	Up-regulation
AGC_Akt_AKT1_ST	Q92547	TOPBP1	P31749	AKT1	S1016	D1023N	1023	Missense	distal	7	no	11.081	11.123	EPSD	GDSC;CCLE	7.780	Up-regulation
AGC_Akt_AKT1_ST	Q92547	TOPBP1	P31749	AKT1	S1159	N1160D	1160	Missense	proximal	1	no	15.377	15.253	PhosphoSitePlus	GDSC;CCLE	7.780	Down-regulation
AGC_Akt_AKT1_ST	Q15672	TWIST1	P31749	AKT1	T121	T121A	121	Missense	central	0	yes	14.091	0.000	PhosphoSitePlus;EPSD	GDSC	7.780	Loss
AGC_Akt_AKT1_ST	Q15672	TWIST1	P31749	AKT1	T121	Q119R	119	Missense	proximal	-2	no	14.091	14.604	PhosphoSitePlus;EPSD	GDSC;CCLE	7.780	Up-regulation
AGC_Akt_AKT1_ST	Q15672	TWIST1	P31749	AKT1	T121	R118L	118	Missense	distal	-3	no	14.091	7.097	PhosphoSitePlus;EPSD	GDSC;CCLE	7.780	Loss
AGC_Akt_AKT1_ST	Q15672	TWIST1	P31749	AKT1	S123	T121A	121	Missense	proximal	-2	no	16.369	15.984	EPSD;PhosphoSitePlus	GDSC	7.780	Down-regulation
AGC_Akt_AKT1_ST	Q15672	TWIST1	P31749	AKT1	S123	Q119R	119	Missense	distal	-4	no	16.369	16.990	EPSD;PhosphoSitePlus	GDSC;CCLE	7.780	Up-regulation
AGC_Akt_AKT1_ST	Q15672	TWIST1	P31749	AKT1	S123	R118L	118	Missense	distal	-5	no	16.369	12.243	EPSD;PhosphoSitePlus	GDSC;CCLE	7.780	Down-regulation
AGC_Akt_AKT1_ST	P00533	EGFR	P31749	AKT1	S227	N234D	234	Missense	distal	7	no	14.385	14.343	EPSD	GDSC;CCLE	7.780	Down-regulation
AGC_Akt_AKT1_ST	P00533	EGFR	P31749	AKT1	S229	N234D	234	Missense	distal	5	no	10.795	10.755	PhosphoSitePlus	GDSC;CCLE	7.780	Down-regulation
AGC_Akt_AKT1_ST	P00533	EGFR	P31749	AKT1	S645	I646L	646	Missense	proximal	1	no	7.881	8.228	EPSD	GDSC;CCLE	7.780	Up-regulation
AGC_Akt_AKT1_ST	P00533	EGFR	P31749	AKT1	S1071	R1068*	1068	Missense	distal	-3	no	10.987	-6.402	EPSD	GDSC	7.780	Loss
AGC_Akt_AKT1_ST	P00533	EGFR	P31749	AKT1	S1071	A1076T	1076	Missense	distal	5	no	10.987	11.038	EPSD	GDSC	7.780	Up-regulation
AGC_Akt_AKT1_ST	Q8TDN4	CABLES1	P31749	AKT1	S242	L248P	248	Missense	distal	6	no	14.471	14.481	EPSD	GDSC;CCLE	7.780	Up-regulation
AGC_Akt_AKT1_ST	Q8TDN4	CABLES1	P31749	AKT1	S242	I247V	247	Missense	distal	5	no	14.471	14.508	EPSD	GDSC;CCLE	7.780	Up-regulation
AGC_Akt_AKT1_ST	Q8TDN4	CABLES1	P31749	AKT1	T415	T419A	419	Missense	distal	4	no	9.748	9.877	PhosphoSitePlus;EPSD	GDSC;CCLE	7.780	Up-regulation
AGC_Akt_AKT1_ST	Q8TDN4	CABLES1	P31749	AKT1	S418	T419A	419	Missense	proximal	1	no	8.321	8.054	EPSD	GDSC;CCLE	7.780	Down-regulation
AGC_Akt_AKT1_ST	P38936	CDKN1A	P31749	AKT1	T145	R143Q	143	Missense	proximal	-2	no	17.056	16.543	EPSD;PhosphoSitePlus	GDSC;CCLE	7.780	Down-regulation
AGC_Akt_AKT1_ST	P38936	CDKN1A	P31749	AKT1	S146	R143Q	143	Missense	distal	-3	no	16.217	9.006	PhosphoSitePlus;EPSD	GDSC;CCLE	7.780	Down-regulation
AGC_Akt_AKT1_ST	P51617	IRAK1	P31749	AKT1	S120	A125T	125	Missense	distal	5	no	11.741	11.792	EPSD	GDSC	7.780	Up-regulation
AGC_Akt_AKT1_ST	P51617	IRAK1	P31749	AKT1	T512	E516K	516	Missense	distal	4	no	10.258	10.157	EPSD	GDSC	7.780	Down-regulation
AGC_Akt_AKT1_ST	O75376	NCOR1	P31749	AKT1	S24	P21T	21	Missense	distal	-3	no	8.966	8.584	EPSD	GDSC;CCLE	7.780	Down-regulation
AGC_Akt_AKT1_ST	O75376	NCOR1	P31749	AKT1	S88	R85S	85	Missense	distal	-3	no	11.655	3.879	EPSD	GDSC;CCLE	7.780	Loss
AGC_Akt_AKT1_ST	O75376	NCOR1	P31749	AKT1	S88	P91L	91	Missense	distal	3	no	11.655	11.639	EPSD	GDSC;CCLE	7.780	Down-regulation
AGC_Akt_AKT1_ST	O75376	NCOR1	P31749	AKT1	S115	P109L	109	Missense	distal	-6	no	9.262	9.275	EPSD	GDSC;CCLE	7.780	Up-regulation
AGC_Akt_AKT1_ST	O75376	NCOR1	P31749	AKT1	S1450	R1445H	1445	Missense	distal	-5	no	15.706	12.611	PhosphoSitePlus	GDSC;CCLE	7.780	Down-regulation
AGC_Akt_AKT1_ST	O75376	NCOR1	P31749	AKT1	S1487	S1480G	1480	Missense	distal	-7	no	9.010	8.824	EPSD	GDSC	7.780	Down-regulation
AGC_Akt_AKT1_ST	O75376	NCOR1	P31749	AKT1	S1760	M1767I	1767	Missense	distal	7	no	9.917	9.878	EPSD	GDSC	7.780	Down-regulation
AGC_Akt_AKT1_ST	O75376	NCOR1	P31749	AKT1	S1760	M1767V	1767	Missense	distal	7	no	9.917	9.920	EPSD	GDSC	7.780	Up-regulation
AGC_Akt_AKT1_ST	O75376	NCOR1	P31749	AKT1	S1955	S1962Y	1962	Missense	distal	7	no	8.599	8.556	EPSD	GDSC;CCLE	7.780	Down-regulation
AGC_Akt_AKT1_ST	O75376	NCOR1	P31749	AKT1	T1968	S1962Y	1962	Missense	distal	-6	no	9.539	9.480	EPSD	GDSC;CCLE	7.780	Down-regulation
AGC_Akt_AKT1_ST	O75376	NCOR1	P31749	AKT1	T1968	Y1966*	1966	Missense	proximal	-2	no	9.539	8.417	EPSD	GDSC	7.780	Down-regulation
AGC_Akt_AKT1_ST	O75376	NCOR1	P31749	AKT1	S1970	Y1966*	1966	Missense	distal	-4	no	9.236	7.452	EPSD	GDSC	7.780	Loss
AGC_Akt_AKT1_ST	O75376	NCOR1	P31749	AKT1	S2117	R2118S	2118	Missense	proximal	1	no	11.593	11.448	EPSD	GDSC;CCLE	7.780	Down-regulation
AGC_Akt_AKT1_ST	O75376	NCOR1	P31749	AKT1	S2328	K2329T	2329	Missense	proximal	1	no	8.086	8.212	EPSD	GDSC;CCLE	7.780	Up-regulation
AGC_Akt_AKT1_ST	O75376	NCOR1	P31749	AKT1	S2377	F2383L	2383	Missense	distal	6	no	9.488	9.504	EPSD	GDSC;CCLE	7.780	Up-regulation
AGC_Akt_AKT1_ST	O75376	NCOR1	P31749	AKT1	S2394	S2395N	2395	Missense	proximal	1	no	11.708	11.620	EPSD	GDSC;CCLE	7.780	Down-regulation
AGC_Akt_AKT1_ST	O75376	NCOR1	P31749	AKT1	T2396	S2395N	2395	Missense	proximal	-1	no	9.216	9.198	EPSD	GDSC;CCLE	7.780	Down-regulation
AGC_Akt_AKT1_ST	P12755	SKI	P31749	AKT1	S377	Q374R	374	Missense	distal	-3	no	4.164	11.375	EPSD	GDSC;CCLE	7.780	Gain
AGC_Akt_AKT1_ST	P12755	SKI	P31749	AKT1	T458	P462A	462	Missense	distal	4	no	16.405	16.373	PhosphoSitePlus	GDSC	7.780	Down-regulation
AGC_Akt_AKT1_ST	P12755	SKI	P31749	AKT1	S495	E490K	490	Missense	distal	-5	no	7.604	9.302	EPSD	GDSC;CCLE	7.780	Gain
AGC_Akt_AKT1_ST	P05106	ITGB3	P31749	AKT1	S619	C614R	614	Missense	distal	-5	no	4.223	8.300	EPSD	GDSC;CCLE	7.780	Gain
AGC_Akt_AKT1_ST	P05106	ITGB3	P31749	AKT1	T777	A776D	776	Missense	proximal	-1	no	9.005	8.977	EPSD	GDSC;CCLE	7.780	Down-regulation
AGC_Akt_AKT1_ST	P05106	ITGB3	P31749	AKT1	S778	A776D	776	Missense	proximal	-2	no	9.215	8.274	EPSD	GDSC;CCLE	7.780	Down-regulation
AGC_Akt_AKT1_ST	P05106	ITGB3	P31749	AKT1	T779	A776D	776	Missense	distal	-3	no	8.504	8.856	PhosphoSitePlus	GDSC;CCLE	7.780	Up-regulation
AGC_Akt_AKT1_ST	Q9BXL7	CARD11	P31749	AKT1	S558	R557H	557	Missense	proximal	-1	no	11.722	11.677	EPSD;PhosphoSitePlus	GDSC	7.780	Down-regulation
AGC_Akt_AKT1_ST	Q9BXL7	CARD11	P31749	AKT1	S620	H617R	617	Missense	distal	-3	no	5.774	10.473	EPSD	GDSC;CCLE	7.780	Gain
AGC_Akt_AKT1_ST	Q9BXL7	CARD11	P31749	AKT1	S622	H617R	617	Missense	distal	-5	no	5.472	8.567	EPSD	GDSC;CCLE	7.780	Gain
AGC_Akt_AKT1_ST	Q9BXL7	CARD11	P31749	AKT1	S644	K642N	642	Missense	proximal	-2	no	12.029	11.093	EPSD;PhosphoSitePlus	GDSC;CCLE	7.780	Down-regulation
AGC_Akt_AKT1_ST	Q9BXL7	CARD11	P31749	AKT1	S652	H658Q	658	Missense	distal	6	no	10.482	10.530	PhosphoSitePlus;EPSD	GDSC;CCLE	7.780	Up-regulation
AGC_Akt_AKT1_ST	Q9BXL7	CARD11	P31749	AKT1	S655	H658Q	658	Missense	distal	3	no	7.875	7.902	EPSD	GDSC;CCLE	7.780	Up-regulation
AGC_Akt_AKT1_ST	Q9BXL7	CARD11	P31749	AKT1	S923	G928R	928	Missense	distal	5	no	14.521	14.591	EPSD	GDSC	7.780	Up-regulation
AGC_Akt_AKT1_ST	Q9BXL7	CARD11	P31749	AKT1	S923	S923L	923	Missense	central	0	yes	14.521	0.000	EPSD	GDSC;CCLE	7.780	Loss
AGC_Akt_AKT1_ST	P08727	KRT19	P31749	AKT1	S35	R32C	32	Missense	distal	-3	no	10.975	4.801	PhosphoSitePlus	GDSC	7.780	Loss
AGC_Akt_AKT1_ST	P08727	KRT19	P31749	AKT1	S128	T132M	132	Missense	distal	4	no	10.090	10.258	EPSD	GDSC;CCLE	7.780	Up-regulation
AGC_Akt_AKT1_ST	P08727	KRT19	P31749	AKT1	T171	E170G	170	Missense	proximal	-1	no	9.225	9.210	EPSD	GDSC;CCLE	7.780	Down-regulation
AGC_Akt_AKT1_ST	P98170	XIAP	P31749	AKT1	S9	D16G	16	Missense	distal	7	no	8.912	8.916	EPSD	GDSC;CCLE	7.780	Up-regulation
AGC_Akt_AKT1_ST	P08047	SP1	P31749	AKT1	S73	A66G	66	Missense	distal	-7	no	11.657	11.620	EPSD	GDSC;CCLE	7.780	Down-regulation
AGC_Akt_AKT1_ST	P08047	SP1	P31749	AKT1	T651	G652D	652	Missense	proximal	1	no	10.632	10.724	EPSD	GDSC;CCLE	7.780	Up-regulation
AGC_Akt_AKT1_ST	P08047	SP1	P31749	AKT1	S670	R669H	669	Missense	proximal	-1	no	9.797	9.753	EPSD	GDSC;CCLE	7.780	Down-regulation
AGC_Akt_AKT1_ST	P49841	GSK3B	P31749	AKT1	T7	T8P	8	Missense	proximal	1	no	11.492	11.143	EPSD	GDSC	7.780	Down-regulation
AGC_Akt_AKT1_ST	P49841	GSK3B	P31749	AKT1	S9	T8P	8	Missense	proximal	-1	no	17.010	16.975	PhosphoSitePlus	GDSC	7.780	Down-regulation
AGC_Akt_AKT1_ST	P49841	GSK3B	P31749	AKT1	S13	T8P	8	Missense	distal	-5	no	7.992	7.712	EPSD	GDSC	7.780	Loss
AGC_Akt_AKT1_ST	P23396	RPS3	P31749	AKT1	T70	R65W	65	Missense	distal	-5	no	14.505	8.985	PhosphoSitePlus	GDSC;CCLE	7.780	Down-regulation
AGC_Akt_AKT1_ST	P23396	RPS3	P31749	AKT1	S149	G155D	155	Missense	distal	6	no	11.883	11.839	EPSD	GDSC;CCLE	7.780	Down-regulation
AGC_Akt_AKT1_ST	P23396	RPS3	P31749	AKT1	S149	R143Q	143	Missense	distal	-6	no	11.883	11.799	EPSD	GDSC;CCLE	7.780	Down-regulation
AGC_Akt_AKT1_ST	Q53EL6	PDCD4	P31749	AKT1	S67	R69W	69	Missense	proximal	2	no	15.873	15.418	PhosphoSitePlus;EPSD	GDSC	7.780	Down-regulation
AGC_Akt_AKT1_ST	Q53EL6	PDCD4	P31749	AKT1	S68	R69W	69	Missense	proximal	1	no	8.819	8.526	EPSD	GDSC	7.780	Down-regulation
AGC_Akt_AKT1_ST	Q53EL6	PDCD4	P31749	AKT1	S76	S80I	80	Missense	distal	4	no	11.265	11.527	EPSD	GDSC;CCLE	7.780	Up-regulation
AGC_Akt_AKT1_ST	Q53EL6	PDCD4	P31749	AKT1	S76	R69W	69	Missense	distal	-7	no	11.265	10.842	EPSD	GDSC	7.780	Down-regulation
AGC_Akt_AKT1_ST	Q53EL6	PDCD4	P31749	AKT1	S78	S80I	80	Missense	proximal	2	no	8.800	8.143	EPSD	GDSC;CCLE	7.780	Down-regulation
AGC_Akt_AKT1_ST	Q53EL6	PDCD4	P31749	AKT1	S313	G307R	307	Missense	distal	-6	no	13.372	13.486	EPSD	GDSC	7.780	Up-regulation
AGC_Akt_AKT1_ST	Q53EL6	PDCD4	P31749	AKT1	T397	S394C	394	Missense	distal	-3	no	7.231	8.834	EPSD	GDSC;CCLE	7.780	Gain
AGC_Akt_AKT1_ST	Q9H6Z4	RANBP3	P31749	AKT1	S333	E329*	329	Missense	distal	-4	no	11.137	9.005	EPSD	GDSC	7.780	Down-regulation
AGC_Akt_AKT1_ST	Q9BVI0	PHF20	P31749	AKT1	S232	S225F	225	Missense	distal	-7	no	9.424	9.147	EPSD	GDSC;CCLE	7.780	Down-regulation
AGC_Akt_AKT1_ST	Q9BVI0	PHF20	P31749	AKT1	S291	E295*	295	Missense	distal	4	no	15.793	16.146	EPSD;PhosphoSitePlus	GDSC	7.780	Up-regulation
AGC_Akt_AKT1_ST	Q9BVI0	PHF20	P31749	AKT1	S328	S324L	324	Missense	distal	-4	no	12.591	11.467	EPSD	GDSC;CCLE	7.780	Down-regulation
AGC_Akt_AKT1_ST	Q9BVI0	PHF20	P31749	AKT1	S329	S324L	324	Missense	distal	-5	no	10.877	11.221	EPSD	GDSC;CCLE	7.780	Up-regulation
AGC_Akt_AKT1_ST	P35226	BMI1	P31749	AKT1	S255	E250K	250	Missense	distal	-5	no	6.660	8.357	EPSD	GDSC;CCLE	7.780	Gain
AGC_Akt_AKT1_ST	P35226	BMI1	P31749	AKT1	S315	N310S	310	Missense	distal	-5	no	8.854	8.868	EPSD	GDSC;CCLE	7.780	Up-regulation
AGC_Akt_AKT1_ST	P35226	BMI1	P31749	AKT1	S316	N310S	310	Missense	distal	-6	no	19.382	19.429	PhosphoSitePlus	GDSC;CCLE	7.780	Up-regulation
AGC_Akt_AKT1_ST	Q96BF3	TMIGD2	P31749	AKT1	S220	S225P	225	Missense	distal	5	no	12.161	12.108	PhosphoSitePlus	GDSC;CCLE	7.780	Down-regulation
AGC_Akt_AKT1_ST	Q96BF3	TMIGD2	P31749	AKT1	S220	T224A	224	Missense	distal	4	no	12.161	12.290	PhosphoSitePlus	GDSC;CCLE	7.780	Up-regulation
AGC_Akt_AKT1_ST	Q96BF3	TMIGD2	P31749	AKT1	S220	T224P	224	Missense	distal	4	no	12.161	12.321	PhosphoSitePlus	GDSC;CCLE	7.780	Up-regulation
AGC_Akt_AKT1_ST	P49760	CLK2	P31749	AKT1	S9	G16W	16	Missense	distal	7	no	13.250	13.232	EPSD	GDSC;CCLE	7.780	Down-regulation
AGC_Akt_AKT1_ST	P49760	CLK2	P31749	AKT1	S9	R5Q	5	Missense	distal	-4	no	13.250	12.629	EPSD	GDSC;CCLE	7.780	Down-regulation
AGC_Akt_AKT1_ST	P49760	CLK2	P31749	AKT1	S9	S9Y	9	Missense	central	0	yes	13.250	0.000	EPSD	GDSC;CCLE	7.780	Loss
AGC_Akt_AKT1_ST	P49760	CLK2	P31749	AKT1	S10	G16W	16	Missense	distal	6	no	9.218	9.164	EPSD	GDSC;CCLE	7.780	Down-regulation
AGC_Akt_AKT1_ST	P49760	CLK2	P31749	AKT1	S10	R5Q	5	Missense	distal	-5	no	9.218	4.991	EPSD	GDSC;CCLE	7.780	Loss
AGC_Akt_AKT1_ST	P49760	CLK2	P31749	AKT1	S10	S9Y	9	Missense	proximal	-1	no	9.218	9.192	EPSD	GDSC;CCLE	7.780	Down-regulation
AGC_Akt_AKT1_ST	P49760	CLK2	P31749	AKT1	S17	G16W	16	Missense	proximal	-1	no	8.588	8.567	EPSD	GDSC;CCLE	7.780	Down-regulation
AGC_Akt_AKT1_ST	P49760	CLK2	P31749	AKT1	S17	S24R	24	Missense	distal	7	no	8.588	8.595	EPSD	GDSC;CCLE	7.780	Up-regulation
AGC_Akt_AKT1_ST	P49760	CLK2	P31749	AKT1	S17	R19H	19	Missense	proximal	2	no	8.588	8.227	EPSD	GDSC;CCLE	7.780	Down-regulation
AGC_Akt_AKT1_ST	P49760	CLK2	P31749	AKT1	S34	S38T	38	Missense	distal	4	no	16.698	16.693	PhosphoSitePlus;EPSD	GDSC	7.780	Down-regulation
AGC_Akt_AKT1_ST	P49760	CLK2	P31749	AKT1	S34	R29*	29	Missense	distal	-5	no	16.698	5.938	PhosphoSitePlus;EPSD	GDSC	7.780	Loss
AGC_Akt_AKT1_ST	P49760	CLK2	P31749	AKT1	S36	S38T	38	Missense	proximal	2	no	17.235	17.160	EPSD	GDSC	7.780	Down-regulation
AGC_Akt_AKT1_ST	P49760	CLK2	P31749	AKT1	S36	R29*	29	Missense	distal	-7	no	17.235	16.458	EPSD	GDSC	7.780	Down-regulation
AGC_Akt_AKT1_ST	P49760	CLK2	P31749	AKT1	S50	R44Q	44	Missense	distal	-6	no	15.690	15.605	EPSD	GDSC;CCLE	7.780	Down-regulation
AGC_Akt_AKT1_ST	P49760	CLK2	P31749	AKT1	S50	D49H	49	Missense	proximal	-1	no	15.690	15.704	EPSD	GDSC;CCLE	7.780	Up-regulation
AGC_Akt_AKT1_ST	P49760	CLK2	P31749	AKT1	S106	R109H	109	Missense	distal	3	no	11.851	11.767	EPSD	GDSC;CCLE	7.780	Down-regulation
AGC_Akt_AKT1_ST	P49760	CLK2	P31749	AKT1	T127	R126W	126	Missense	proximal	-1	no	15.979	15.918	EPSD;PhosphoSitePlus	GDSC	7.780	Down-regulation
AGC_Akt_AKT1_ST	P49760	CLK2	P31749	AKT1	T127	S132Y	132	Missense	distal	5	no	15.979	15.936	EPSD;PhosphoSitePlus	GDSC;CCLE	7.780	Down-regulation
AGC_Akt_AKT1_ST	P49760	CLK2	P31749	AKT1	S133	R126W	126	Missense	distal	-7	no	13.315	12.892	EPSD	GDSC	7.780	Down-regulation
AGC_Akt_AKT1_ST	P49760	CLK2	P31749	AKT1	S133	S132Y	132	Missense	proximal	-1	no	13.315	13.289	EPSD	GDSC;CCLE	7.780	Down-regulation
AGC_Akt_AKT1_ST	O60825	PFKFB2	P31749	AKT1	S29	M23T	23	Missense	distal	-6	no	8.511	8.604	EPSD	GDSC;CCLE	7.780	Up-regulation
AGC_Akt_AKT1_ST	O60825	PFKFB2	P31749	AKT1	T52	R49Q	49	Missense	distal	-3	no	10.138	2.927	EPSD	GDSC;CCLE	7.780	Loss
AGC_Akt_AKT1_ST	O60825	PFKFB2	P31749	AKT1	T52	V54M	54	Missense	proximal	2	no	10.138	10.260	EPSD	GDSC	7.780	Up-regulation
AGC_Akt_AKT1_ST	O60825	PFKFB2	P31749	AKT1	T52	R49L	49	Missense	distal	-3	no	10.138	3.145	EPSD	GDSC;CCLE	7.780	Loss
AGC_Akt_AKT1_ST	O60825	PFKFB2	P31749	AKT1	T59	V54M	54	Missense	distal	-5	no	8.764	8.557	EPSD	GDSC	7.780	Down-regulation
AGC_Akt_AKT1_ST	O60825	PFKFB2	P31749	AKT1	S466	S472G	472	Missense	distal	6	no	16.116	16.011	PhosphoSitePlus;EPSD	GDSC;CCLE	7.780	Down-regulation
AGC_Akt_AKT1_ST	O60825	PFKFB2	P31749	AKT1	T468	S472G	472	Missense	distal	4	no	7.975	8.149	EPSD	GDSC;CCLE	7.780	Up-regulation
AGC_Akt_AKT1_ST	O60825	PFKFB2	P31749	AKT1	S483	P488L	488	Missense	distal	5	no	16.631	16.617	EPSD;PhosphoSitePlus	GDSC;CCLE	7.780	Down-regulation
AGC_Akt_AKT1_ST	O60825	PFKFB2	P31749	AKT1	S493	P494A	494	Missense	proximal	1	no	8.042	8.124	EPSD	GDSC;CCLE	7.780	Up-regulation
AGC_Akt_AKT1_ST	O60825	PFKFB2	P31749	AKT1	S493	Q498L	498	Missense	distal	5	no	8.042	8.019	EPSD	GDSC;CCLE	7.780	Down-regulation
AGC_Akt_AKT1_ST	O60825	PFKFB2	P31749	AKT1	S493	R496C	496	Missense	distal	3	no	8.042	7.881	EPSD	GDSC	7.780	Down-regulation
AGC_Akt_AKT1_ST	O60825	PFKFB2	P31749	AKT1	S493	M500L	500	Missense	distal	7	no	8.042	8.035	EPSD	GDSC;CCLE	7.780	Down-regulation
AGC_Akt_AKT1_ST	O60825	PFKFB2	P31749	AKT1	S493	P488L	488	Missense	distal	-5	no	8.042	7.926	EPSD	GDSC;CCLE	7.780	Down-regulation
AGC_Akt_AKT1_ST	Q14CB8	ARHGAP19	P31749	AKT1	S420	R421H	421	Missense	proximal	1	no	13.320	12.997	EPSD	GDSC	7.780	Down-regulation
AGC_Akt_AKT1_ST	Q14CB8	ARHGAP19	P31749	AKT1	S422	R421H	421	Missense	proximal	-1	no	15.684	15.640	PhosphoSitePlus	GDSC	7.780	Down-regulation
AGC_Akt_AKT1_ST	Q14CB8	ARHGAP19	P31749	AKT1	S424	R421H	421	Missense	distal	-3	no	16.448	11.749	EPSD	GDSC	7.780	Down-regulation
AGC_Akt_AKT1_ST	O60285	NUAK1	P31749	AKT1	S266	E272K	272	Missense	distal	6	no	11.701	11.770	EPSD	GDSC;CCLE	7.780	Up-regulation
AGC_Akt_AKT1_ST	O60285	NUAK1	P31749	AKT1	S266	R271Q	271	Missense	distal	5	no	11.701	11.650	EPSD	GDSC;CCLE	7.780	Down-regulation
AGC_Akt_AKT1_ST	O60285	NUAK1	P31749	AKT1	S413	I417V	417	Missense	distal	4	no	11.837	11.756	EPSD	GDSC;CCLE	7.780	Down-regulation
AGC_Akt_AKT1_ST	O60285	NUAK1	P31749	AKT1	S516	V512L	512	Missense	distal	-4	no	8.923	8.894	EPSD	GDSC;CCLE	7.780	Down-regulation
AGC_Akt_AKT1_ST	O60285	NUAK1	P31749	AKT1	S518	V512L	512	Missense	distal	-6	no	7.980	8.005	EPSD	GDSC;CCLE	7.780	Up-regulation
AGC_Akt_AKT1_ST	O60285	NUAK1	P31749	AKT1	S600	R595L	595	Missense	distal	-5	no	14.420	10.294	PhosphoSitePlus	GDSC	7.780	Down-regulation
AGC_Akt_AKT1_ST	O60285	NUAK1	P31749	AKT1	S600	R599L	599	Missense	proximal	-1	no	14.420	14.381	PhosphoSitePlus	GDSC;CCLE	7.780	Down-regulation
AGC_Akt_AKT1_ST	O60285	NUAK1	P31749	AKT1	S600	S600N	600	Missense	central	0	yes	14.420	0.000	PhosphoSitePlus	GDSC;CCLE	7.780	Loss
AGC_Akt_AKT1_ST	Q5XUX0	FBXO31	P31749	AKT1	T127	V129M	129	Missense	proximal	2	no	8.142	8.264	EPSD	GDSC;CCLE	7.780	Up-regulation
AGC_Akt_AKT1_ST	Q5XUX0	FBXO31	P31749	AKT1	T127	L124V	124	Missense	distal	-3	no	8.142	8.271	EPSD	GDSC	7.780	Up-regulation
AGC_Akt_AKT1_ST	Q5XUX0	FBXO31	P31749	AKT1	S403	E399K	399	Missense	distal	-4	no	8.709	9.293	EPSD	GDSC;CCLE	7.780	Up-regulation
AGC_Akt_AKT1_ST	Q9Y283	INVS	P31749	AKT1	S126	S126N	126	Missense	central	0	yes	11.587	0.000	EPSD	GDSC;CCLE	7.780	Loss
AGC_Akt_AKT1_ST	Q9Y283	INVS	P31749	AKT1	S700	R706G	706	Missense	distal	6	no	8.086	7.982	EPSD	GDSC	7.780	Down-regulation
AGC_Akt_AKT1_ST	Q9UPY5	SLC7A11	P31749	AKT1	S8	V2I	2	Missense	distal	-6	no	9.813	9.768	EPSD	GDSC;CCLE	7.780	Down-regulation
AGC_Akt_AKT1_ST	Q9UPY5	SLC7A11	P31749	AKT1	S26	G28S	28	Missense	proximal	2	no	10.440	10.772	PhosphoSitePlus	GDSC;CCLE	7.780	Up-regulation
AGC_Akt_AKT1_ST	Q9UPY5	SLC7A11	P31749	AKT1	S26	N21K	21	Missense	distal	-5	no	10.440	12.527	PhosphoSitePlus	GDSC;CCLE	7.780	Up-regulation
AGC_Akt_AKT1_ST	O43524	FOXO3	P31749	AKT1	S253	R249W	249	Missense	distal	-4	no	16.516	14.967	EPSD;PhosphoSitePlus	GDSC;CCLE	7.780	Down-regulation
AGC_Akt_AKT1_ST	O43524	FOXO3	P31749	AKT1	T313	V320I	320	Missense	distal	7	no	10.817	10.774	EPSD	GDSC;CCLE	7.780	Down-regulation
AGC_Akt_AKT1_ST	O43524	FOXO3	P31749	AKT1	S315	V320I	320	Missense	distal	5	no	16.048	16.011	EPSD	GDSC;CCLE	7.780	Down-regulation
AGC_Akt_AKT1_ST	O43524	FOXO3	P31749	AKT1	S413	R410W	410	Missense	distal	-3	no	11.407	2.467	EPSD	GDSC;CCLE	7.780	Loss
AGC_Akt_AKT1_ST	O43524	FOXO3	P31749	AKT1	S413	M408V	408	Missense	distal	-5	no	11.407	11.615	EPSD	GDSC;CCLE	7.780	Up-regulation
AGC_Akt_AKT1_ST	P46527	CDKN1B	P31749	AKT1	T157	P155L	155	Missense	proximal	-2	no	13.829	13.797	PhosphoSitePlus;EPSD	GDSC;CCLE	7.780	Down-regulation
AGC_Akt_AKT1_ST	P84103	SRSF3	P31749	AKT1	S95	G91D	91	Missense	distal	-4	no	8.835	8.276	EPSD	GDSC;CCLE	7.780	Down-regulation
AGC_Akt_AKT1_ST	P84103	SRSF3	P31749	AKT1	S95	W96*	96	Missense	proximal	1	no	8.835	8.479	EPSD	GDSC	7.780	Down-regulation
AGC_Akt_AKT1_ST	P84103	SRSF3	P31749	AKT1	S115	R118K	118	Missense	distal	3	no	12.485	12.503	EPSD	GDSC;CCLE	7.780	Up-regulation
AGC_Akt_AKT1_ST	P84103	SRSF3	P31749	AKT1	S120	R118K	118	Missense	proximal	-2	no	11.984	12.423	EPSD	GDSC;CCLE	7.780	Up-regulation
AGC_Akt_AKT1_ST	P84103	SRSF3	P31749	AKT1	S122	R118K	118	Missense	distal	-4	no	16.112	16.098	EPSD;PhosphoSitePlus	GDSC;CCLE	7.780	Down-regulation
AGC_Akt_AKT1_ST	P84103	SRSF3	P31749	AKT1	S124	R118K	118	Missense	distal	-6	no	10.269	10.254	EPSD	GDSC;CCLE	7.780	Down-regulation
AGC_Akt_AKT1_ST	P84103	SRSF3	P31749	AKT1	S148	R153M	153	Missense	distal	5	no	13.610	13.546	EPSD	GDSC;CCLE	7.780	Down-regulation
AGC_Akt_AKT1_ST	P84103	SRSF3	P31749	AKT1	S150	R153M	153	Missense	distal	3	no	10.841	10.772	EPSD	GDSC;CCLE	7.780	Down-regulation
AGC_Akt_AKT1_ST	P84103	SRSF3	P31749	AKT1	S152	R153M	153	Missense	proximal	1	no	14.444	14.236	EPSD	GDSC;CCLE	7.780	Down-regulation
AGC_Akt_AKT1_ST	P84103	SRSF3	P31749	AKT1	S152	R159S	159	Missense	distal	7	no	14.444	14.437	EPSD	GDSC;CCLE	7.780	Down-regulation
AGC_Akt_AKT1_ST	P84103	SRSF3	P31749	AKT1	S154	R153M	153	Missense	proximal	-1	no	14.977	14.938	EPSD	GDSC;CCLE	7.780	Down-regulation
AGC_Akt_AKT1_ST	P84103	SRSF3	P31749	AKT1	S154	R159S	159	Missense	distal	5	no	14.977	14.970	EPSD	GDSC;CCLE	7.780	Down-regulation
AGC_Akt_AKT1_ST	P84103	SRSF3	P31749	AKT1	S156	R153M	153	Missense	distal	-3	no	15.818	8.312	EPSD	GDSC;CCLE	7.780	Down-regulation
AGC_Akt_AKT1_ST	P84103	SRSF3	P31749	AKT1	S156	R159S	159	Missense	distal	3	no	15.818	15.834	EPSD	GDSC;CCLE	7.780	Up-regulation
AGC_Akt_AKT1_ST	P84103	SRSF3	P31749	AKT1	S158	R153M	153	Missense	distal	-5	no	18.645	14.122	EPSD	GDSC;CCLE	7.780	Down-regulation
AGC_Akt_AKT1_ST	P84103	SRSF3	P31749	AKT1	S158	R159S	159	Missense	proximal	1	no	18.645	18.500	EPSD	GDSC;CCLE	7.780	Down-regulation
AGC_Akt_AKT1_ST	P84103	SRSF3	P31749	AKT1	S160	R153M	153	Missense	distal	-7	no	18.378	18.106	EPSD	GDSC;CCLE	7.780	Down-regulation
AGC_Akt_AKT1_ST	P84103	SRSF3	P31749	AKT1	S160	R159S	159	Missense	proximal	-1	no	18.378	18.368	EPSD	GDSC;CCLE	7.780	Down-regulation
AGC_Akt_AKT1_ST	Q92794	KAT6A	P31749	AKT1	T332	P334L	334	Missense	proximal	2	no	9.379	9.170	EPSD	GDSC;CCLE	7.780	Down-regulation
AGC_Akt_AKT1_ST	Q92794	KAT6A	P31749	AKT1	T369	R362S	362	Missense	distal	-7	no	17.379	17.323	PhosphoSitePlus	GDSC	7.780	Down-regulation
AGC_Akt_AKT1_ST	Q92794	KAT6A	P31749	AKT1	S399	D395E	395	Missense	distal	-4	no	7.654	8.430	EPSD	GDSC	7.780	Gain
AGC_Akt_AKT1_ST	Q92794	KAT6A	P31749	AKT1	S985	G983C	983	Missense	proximal	-2	no	9.520	8.562	EPSD	GDSC;CCLE	7.780	Down-regulation
AGC_Akt_AKT1_ST	Q92794	KAT6A	P31749	AKT1	S987	G983C	983	Missense	distal	-4	no	10.278	9.414	EPSD	GDSC;CCLE	7.780	Down-regulation
AGC_Akt_AKT1_ST	Q9UKV3	ACIN1	P31749	AKT1	T9	R3G	3	Missense	distal	-6	no	11.750	11.636	EPSD	GDSC;CCLE	7.780	Down-regulation
AGC_Akt_AKT1_ST	Q9UKV3	ACIN1	P31749	AKT1	S10	R3G	3	Missense	distal	-7	no	8.812	8.570	EPSD	GDSC;CCLE	7.780	Down-regulation
AGC_Akt_AKT1_ST	Q9UKV3	ACIN1	P31749	AKT1	S229	A234V	234	Missense	distal	5	no	11.478	11.470	EPSD	GDSC	7.780	Down-regulation
AGC_Akt_AKT1_ST	Q9UKV3	ACIN1	P31749	AKT1	S240	A234V	234	Missense	distal	-6	no	9.060	9.039	EPSD	GDSC	7.780	Down-regulation
AGC_Akt_AKT1_ST	Q9UKV3	ACIN1	P31749	AKT1	S561	H568Y	568	Missense	distal	7	no	10.184	10.205	EPSD	GDSC;CCLE	7.780	Up-regulation
AGC_Akt_AKT1_ST	Q9UKV3	ACIN1	P31749	AKT1	T563	H568Y	568	Missense	distal	5	no	8.730	8.753	EPSD	GDSC;CCLE	7.780	Up-regulation
AGC_Akt_AKT1_ST	Q9UKV3	ACIN1	P31749	AKT1	S583	S583L	583	Missense	central	0	yes	12.629	0.000	EPSD	GDSC;CCLE	7.780	Loss
AGC_Akt_AKT1_ST	Q9UKV3	ACIN1	P31749	AKT1	S585	S583L	583	Missense	proximal	-2	no	10.277	9.421	EPSD	GDSC;CCLE	7.780	Down-regulation
AGC_Akt_AKT1_ST	Q9UKV3	ACIN1	P31749	AKT1	S593	D597G	597	Missense	distal	4	no	13.530	13.479	EPSD	GDSC;CCLE	7.780	Down-regulation
AGC_Akt_AKT1_ST	Q9UKV3	ACIN1	P31749	AKT1	S595	R602Q	602	Missense	distal	7	no	16.348	16.292	EPSD	GDSC	7.780	Down-regulation
AGC_Akt_AKT1_ST	Q9UKV3	ACIN1	P31749	AKT1	S595	D597G	597	Missense	proximal	2	no	16.348	16.615	EPSD	GDSC;CCLE	7.780	Up-regulation
AGC_Akt_AKT1_ST	Q9UKV3	ACIN1	P31749	AKT1	S599	R602Q	602	Missense	distal	3	no	9.211	9.155	EPSD	GDSC	7.780	Down-regulation
AGC_Akt_AKT1_ST	Q9UKV3	ACIN1	P31749	AKT1	S599	D597G	597	Missense	proximal	-2	no	9.211	9.910	EPSD	GDSC;CCLE	7.780	Up-regulation
AGC_Akt_AKT1_ST	Q9UKV3	ACIN1	P31749	AKT1	S605	R602Q	602	Missense	distal	-3	no	10.344	3.133	EPSD	GDSC	7.780	Loss
AGC_Akt_AKT1_ST	Q9UKV3	ACIN1	P31749	AKT1	S631	S637P	637	Missense	distal	6	no	10.506	10.412	EPSD	GDSC;CCLE	7.780	Down-regulation
AGC_Akt_AKT1_ST	Q9UKV3	ACIN1	P31749	AKT1	S635	S637P	637	Missense	proximal	2	no	13.515	13.179	EPSD	GDSC;CCLE	7.780	Down-regulation
AGC_Akt_AKT1_ST	Q9UKV3	ACIN1	P31749	AKT1	S635	R642C	642	Missense	distal	7	no	13.515	13.385	EPSD	GDSC	7.780	Down-regulation
AGC_Akt_AKT1_ST	Q9UKV3	ACIN1	P31749	AKT1	S637	S637P	637	Missense	central	0	yes	9.196	0.000	EPSD	GDSC;CCLE	7.780	Loss
AGC_Akt_AKT1_ST	Q9UKV3	ACIN1	P31749	AKT1	S637	R642C	642	Missense	distal	5	no	9.196	9.070	EPSD	GDSC	7.780	Down-regulation
AGC_Akt_AKT1_ST	Q9UKV3	ACIN1	P31749	AKT1	S643	S637P	637	Missense	distal	-6	no	16.166	16.102	EPSD	GDSC;CCLE	7.780	Down-regulation
AGC_Akt_AKT1_ST	Q9UKV3	ACIN1	P31749	AKT1	S643	R642C	642	Missense	proximal	-1	no	16.166	16.096	EPSD	GDSC	7.780	Down-regulation
AGC_Akt_AKT1_ST	Q9UKV3	ACIN1	P31749	AKT1	S645	R642C	642	Missense	distal	-3	no	16.880	10.707	EPSD	GDSC	7.780	Down-regulation
AGC_Akt_AKT1_ST	Q9UKV3	ACIN1	P31749	AKT1	S647	R642C	642	Missense	distal	-5	no	16.700	12.623	EPSD	GDSC	7.780	Down-regulation
AGC_Akt_AKT1_ST	Q9UKV3	ACIN1	P31749	AKT1	S649	R642C	642	Missense	distal	-7	no	15.202	14.723	EPSD	GDSC	7.780	Down-regulation
AGC_Akt_AKT1_ST	Q9UKV3	ACIN1	P31749	AKT1	T699	E695D	695	Missense	distal	-4	no	12.101	11.324	EPSD	GDSC;CCLE	7.780	Down-regulation
AGC_Akt_AKT1_ST	Q9UKV3	ACIN1	P31749	AKT1	S701	E695D	695	Missense	distal	-6	no	9.519	9.447	EPSD	GDSC;CCLE	7.780	Down-regulation
AGC_Akt_AKT1_ST	Q9UKV3	ACIN1	P31749	AKT1	S815	K811N	811	Missense	distal	-4	no	8.218	7.579	EPSD	GDSC;CCLE	7.780	Loss
AGC_Akt_AKT1_ST	Q9UKV3	ACIN1	P31749	AKT1	S815	K821R	821	Missense	distal	6	no	8.218	8.206	EPSD	GDSC;CCLE	7.780	Down-regulation
AGC_Akt_AKT1_ST	Q9UKV3	ACIN1	P31749	AKT1	S825	K821R	821	Missense	distal	-4	no	13.846	13.860	EPSD	GDSC;CCLE	7.780	Up-regulation
AGC_Akt_AKT1_ST	Q9UKV3	ACIN1	P31749	AKT1	S983	R979*	979	Missense	distal	-4	no	12.353	9.624	EPSD	GDSC	7.780	Down-regulation
AGC_Akt_AKT1_ST	Q9UKV3	ACIN1	P31749	AKT1	T1159	R1156W	1156	Missense	distal	-3	no	11.318	2.377	EPSD	GDSC;CCLE	7.780	Loss
AGC_Akt_AKT1_ST	Q9UKV3	ACIN1	P31749	AKT1	S1161	R1156W	1156	Missense	distal	-5	no	14.927	9.407	EPSD	GDSC;CCLE	7.780	Down-regulation
AGC_Akt_AKT1_ST	Q9UKV3	ACIN1	P31749	AKT1	S1176	R1181H	1181	Missense	distal	5	no	8.383	8.309	EPSD	GDSC;CCLE	7.780	Down-regulation
AGC_Akt_AKT1_ST	Q9UKV3	ACIN1	P31749	AKT1	S1178	R1181H	1181	Missense	distal	3	no	12.207	12.123	EPSD	GDSC;CCLE	7.780	Down-regulation
AGC_Akt_AKT1_ST	Q9UKV3	ACIN1	P31749	AKT1	S1180	R1181H	1181	Missense	proximal	1	no	16.215	15.893	PhosphoSitePlus	GDSC;CCLE	7.780	Down-regulation
AGC_Akt_AKT1_ST	Q9UKV3	ACIN1	P31749	AKT1	S1325	T1321I	1321	Missense	distal	-4	no	9.002	7.565	EPSD	GDSC	7.780	Loss
AGC_Akt_AKT1_ST	Q9UKV3	ACIN1	P31749	AKT1	S1327	T1321I	1321	Missense	distal	-6	no	13.043	12.892	EPSD	GDSC	7.780	Down-regulation
AGC_Akt_AKT1_ST	Q07352	ZFP36L1	P31749	AKT1	T148	L144F	144	Missense	distal	-4	no	10.497	10.453	EPSD	GDSC;CCLE	7.780	Down-regulation
AGC_Akt_AKT1_ST	Q14315	FLNC	P31749	AKT1	T423	V426M	426	Missense	distal	3	no	9.759	9.764	EPSD	GDSC;CCLE	7.780	Up-regulation
AGC_Akt_AKT1_ST	Q14315	FLNC	P31749	AKT1	S729	Y730S	730	Missense	proximal	1	no	8.740	8.747	EPSD	GDSC;CCLE	7.780	Up-regulation
AGC_Akt_AKT1_ST	Q14315	FLNC	P31749	AKT1	S1007	C1013Y	1013	Missense	distal	6	no	9.815	9.929	EPSD	GDSC;CCLE	7.780	Up-regulation
AGC_Akt_AKT1_ST	Q14315	FLNC	P31749	AKT1	T1281	S1279T	1279	Missense	proximal	-2	no	12.372	12.306	EPSD	GDSC;CCLE	7.780	Down-regulation
AGC_Akt_AKT1_ST	Q14315	FLNC	P31749	AKT1	T2179	L2174M	2174	Missense	distal	-5	no	12.798	12.402	EPSD	GDSC;CCLE	7.780	Down-regulation
AGC_Akt_AKT1_ST	Q14315	FLNC	P31749	AKT1	T2179	R2173P	2173	Missense	distal	-6	no	12.798	12.700	EPSD	GDSC;CCLE	7.780	Down-regulation
AGC_Akt_AKT1_ST	Q14315	FLNC	P31749	AKT1	S2181	L2174M	2174	Missense	distal	-7	no	11.571	11.588	EPSD	GDSC;CCLE	7.780	Up-regulation
AGC_Akt_AKT1_ST	Q14315	FLNC	P31749	AKT1	S2233	R2230H	2230	Missense	distal	-3	no	15.302	10.603	PhosphoSitePlus	GDSC	7.780	Down-regulation
AGC_Akt_AKT1_ST	Q14315	FLNC	P31749	AKT1	T2412	D2406N	2406	Missense	distal	-6	no	12.147	12.218	EPSD	GDSC;CCLE	7.780	Up-regulation
AGC_Akt_AKT1_ST	Q14315	FLNC	P31749	AKT1	S2624	R2621Q	2621	Missense	distal	-3	no	12.121	4.910	EPSD	GDSC	7.780	Loss
AGC_Akt_AKT1_ST	Q14315	FLNC	P31749	AKT1	S2626	R2621Q	2621	Missense	distal	-5	no	8.485	4.258	EPSD	GDSC	7.780	Loss
AGC_Akt_AKT1_ST	Q15027	ACAP1	P31749	AKT1	S731	D736N	736	Missense	distal	5	no	9.397	9.437	EPSD	GDSC;CCLE	7.780	Up-regulation
AGC_Akt_AKT1_ST	Q13107	USP4	P31749	AKT1	S595	Y601C	601	Missense	distal	6	no	8.917	8.803	EPSD	GDSC;CCLE	7.780	Down-regulation
AGC_Akt_AKT1_ST	P03372	ESR1	P31749	AKT1	S154	R151H	151	Missense	distal	-3	no	11.303	6.604	EPSD	GDSC	7.780	Loss
AGC_Akt_AKT1_ST	P03372	ESR1	P31749	AKT1	S154	G160S	160	Missense	distal	6	no	11.303	11.408	EPSD	GDSC	7.780	Up-regulation
AGC_Akt_AKT1_ST	P03372	ESR1	P31749	AKT1	S167	G160S	160	Missense	distal	-7	no	16.129	16.316	PhosphoSitePlus;EPSD	GDSC	7.780	Up-regulation
AGC_Akt_AKT1_ST	P03372	ESR1	P31749	AKT1	S167	R164I	164	Missense	distal	-3	no	16.129	9.049	PhosphoSitePlus;EPSD	GDSC;CCLE	7.780	Down-regulation
AGC_Akt_AKT1_ST	P03372	ESR1	P31749	AKT1	S236	R241L	241	Missense	distal	5	no	13.602	13.528	EPSD	GDSC;CCLE	7.780	Down-regulation
AGC_Akt_AKT1_ST	P03372	ESR1	P31749	AKT1	S305	K299N	299	Missense	distal	-6	no	12.276	12.209	EPSD;PhosphoSitePlus	GDSC;CCLE	7.780	Down-regulation
AGC_Akt_AKT1_ST	P03372	ESR1	P31749	AKT1	S305	I298V	298	Missense	distal	-7	no	12.276	12.370	EPSD;PhosphoSitePlus	GDSC	7.780	Up-regulation
AGC_Akt_AKT1_ST	P24941	CDK2	P31749	AKT1	T160	P155L	155	Missense	distal	-5	no	10.875	10.759	EPSD	GDSC;CCLE	7.780	Down-regulation
AGC_Akt_AKT1_ST	P15056	BRAF	P31749	AKT1	S363	D361G	361	Missense	proximal	-2	no	12.988	13.686	EPSD	GDSC;CCLE	7.780	Up-regulation
AGC_Akt_AKT1_ST	P15056	BRAF	P31749	AKT1	S365	D361G	361	Missense	distal	-4	no	16.893	17.451	PhosphoSitePlus;EPSD	GDSC;CCLE	7.780	Up-regulation
AGC_Akt_AKT1_ST	P15056	BRAF	P31749	AKT1	S394	A400V	400	Missense	distal	6	no	9.120	9.089	EPSD	GDSC;CCLE	7.780	Down-regulation
AGC_Akt_AKT1_ST	P15056	BRAF	P31749	AKT1	T740	A747V	747	Missense	distal	7	no	8.293	8.289	EPSD	GDSC;CCLE	7.780	Down-regulation
AGC_Akt_AKT1_ST	Q9Y2V2	CARHSP1	P31749	AKT1	T50	A53E	53	Missense	distal	3	no	13.027	13.044	EPSD	GDSC	7.780	Up-regulation
AGC_Akt_AKT1_ST	Q9Y2V2	CARHSP1	P31749	AKT1	S52	A53E	53	Missense	proximal	1	no	17.128	17.106	PhosphoSitePlus	GDSC	7.780	Down-regulation
AGC_Akt_AKT1_ST	Q9Y2V2	CARHSP1	P31749	AKT1	T54	A53E	53	Missense	proximal	-1	no	12.372	12.378	EPSD	GDSC	7.780	Up-regulation
AGC_Akt_AKT1_ST	O14745	SLC9A3R1	P31749	AKT1	T156	R151W	151	Missense	distal	-5	no	14.210	8.690	PhosphoSitePlus	GDSC	7.780	Down-regulation
AGC_Akt_AKT1_ST	O14745	SLC9A3R1	P31749	AKT1	S340	S340N	340	Missense	central	0	yes	10.058	0.000	EPSD	GDSC;CCLE	7.780	Loss
AGC_Akt_AKT1_ST	P53365	ARFIP2	P31749	AKT1	S72	R69H	69	Missense	distal	-3	no	12.451	7.752	EPSD	GDSC;CCLE	7.780	Loss
AGC_Akt_AKT1_ST	P53365	ARFIP2	P31749	AKT1	S72	P71A	71	Missense	proximal	-1	no	12.451	12.459	EPSD	GDSC;CCLE	7.780	Up-regulation
AGC_Akt_AKT1_ST	P53365	ARFIP2	P31749	AKT1	S74	R69H	69	Missense	distal	-5	no	9.738	6.643	EPSD	GDSC;CCLE	7.780	Loss
AGC_Akt_AKT1_ST	P53365	ARFIP2	P31749	AKT1	S74	P71A	71	Missense	distal	-3	no	9.738	10.075	EPSD	GDSC;CCLE	7.780	Up-regulation
AGC_Akt_AKT1_ST	Q05195	MXD1	P31749	AKT1	S194	G196D	196	Missense	proximal	2	no	8.343	8.076	EPSD	GDSC;CCLE	7.780	Down-regulation
AGC_Akt_AKT1_ST	P62753	RPS6	P31749	AKT1	S235	S242F	242	Missense	distal	7	no	16.340	16.267	EPSD	GDSC	7.780	Down-regulation
AGC_Akt_AKT1_ST	P62753	RPS6	P31749	AKT1	S236	S242F	242	Missense	distal	6	no	18.528	18.409	PhosphoSitePlus	GDSC	7.780	Down-regulation
AGC_Akt_AKT1_ST	P62753	RPS6	P31749	AKT1	S240	S242F	242	Missense	proximal	2	no	8.495	7.918	EPSD	GDSC	7.780	Down-regulation
AGC_Akt_AKT1_ST	P62753	RPS6	P31749	AKT1	T241	S242F	242	Missense	proximal	1	no	12.988	13.006	EPSD	GDSC	7.780	Up-regulation
AGC_Akt_AKT1_ST	P62753	RPS6	P31749	AKT1	S242	S242F	242	Missense	central	0	yes	7.853	0.000	EPSD	GDSC	7.780	Loss
AGC_Akt_AKT1_ST	P62753	RPS6	P31749	AKT1	S246	S242F	242	Missense	distal	-4	no	11.038	9.870	EPSD	GDSC	7.780	Down-regulation
AGC_Akt_AKT1_ST	Q14457	BECN1	P31749	AKT1	S10	Q13*	13	Missense	distal	3	no	8.163	8.044	EPSD	GDSC	7.780	Down-regulation
AGC_Akt_AKT1_ST	Q14457	BECN1	P31749	AKT1	S10	S10N	10	Missense	central	0	yes	8.163	0.000	EPSD	GDSC;CCLE	7.780	Loss
AGC_Akt_AKT1_ST	P67809	YBX1	P31749	AKT1	S102	N95I	95	Missense	distal	-7	no	8.722	8.465	PhosphoSitePlus	GDSC;CCLE	7.780	Down-regulation
AGC_Akt_AKT1_ST	P67809	YBX1	P31749	AKT1	S209	G203A	203	Missense	distal	-6	no	9.316	9.340	EPSD	GDSC;CCLE	7.780	Up-regulation
AGC_Akt_AKT1_ST	P67809	YBX1	P31749	AKT1	T271	G268R	268	Missense	distal	-3	no	2.127	8.883	EPSD	GDSC	7.780	Gain
AGC_Akt_AKT1_ST	Q13131	PRKAA1	P31749	AKT1	T37	G34R	34	Missense	distal	-3	no	2.976	9.732	EPSD	GDSC;CCLE	7.780	Gain
AGC_Akt_AKT1_ST	Q9UQC2	GAB2	P31749	AKT1	T225	T225I	225	Missense	central	0	yes	10.382	0.000	EPSD	GDSC;CCLE	7.780	Loss
AGC_Akt_AKT1_ST	Q9UQC2	GAB2	P31749	AKT1	T259	S264G	264	Missense	distal	5	no	10.546	10.483	EPSD	GDSC	7.780	Down-regulation
AGC_Akt_AKT1_ST	Q9UQC2	GAB2	P31749	AKT1	S264	S264G	264	Missense	central	0	yes	8.031	0.000	EPSD	GDSC	7.780	Loss
AGC_Akt_AKT1_ST	Q9UQC2	GAB2	P31749	AKT1	T265	S264G	264	Missense	proximal	-1	no	7.788	7.758	EPSD	GDSC	7.780	Loss
AGC_Akt_AKT1_ST	Q9UQC2	GAB2	P31749	AKT1	T385	T391P	391	Missense	distal	6	no	9.593	9.479	EPSD	GDSC	7.780	Down-regulation
AGC_Akt_AKT1_ST	Q9UQC2	GAB2	P31749	AKT1	T385	R389C	389	Missense	distal	4	no	9.593	9.927	EPSD	GDSC;CCLE	7.780	Up-regulation
AGC_Akt_AKT1_ST	Q9UQC2	GAB2	P31749	AKT1	T391	T391P	391	Missense	central	0	yes	9.409	0.000	EPSD	GDSC	7.780	Loss
AGC_Akt_AKT1_ST	Q9UQC2	GAB2	P31749	AKT1	T391	R389C	389	Missense	proximal	-2	no	9.409	7.945	EPSD	GDSC;CCLE	7.780	Down-regulation
AGC_Akt_AKT1_ST	Q9UQC2	GAB2	P31749	AKT1	S445	R442L	442	Missense	distal	-3	no	11.344	4.350	EPSD	GDSC;CCLE	7.780	Loss
AGC_Akt_AKT1_ST	P23769	GATA2	P31749	AKT1	S340	G346S	346	Missense	distal	6	no	10.890	10.996	EPSD	GDSC;CCLE	7.780	Up-regulation
AGC_Akt_AKT1_ST	Q05397	PTK2	P31749	AKT1	S17	N15S	15	Missense	proximal	-2	no	7.537	8.223	EPSD	GDSC	7.780	Gain
AGC_Akt_AKT1_ST	Q05397	PTK2	P31749	AKT1	S517	S517C	517	Missense	central	0	yes	12.096	0.000	EPSD	GDSC;CCLE	7.780	Loss
AGC_Akt_AKT1_ST	P54253	ATXN1	P31749	AKT1	T22	I19T	19	Missense	distal	-3	no	8.868	8.927	EPSD	GDSC	7.780	Up-regulation
AGC_Akt_AKT1_ST	P54253	ATXN1	P31749	AKT1	S775	E778Q	778	Missense	distal	3	no	17.674	17.642	PhosphoSitePlus	GDSC;CCLE	7.780	Down-regulation
AGC_Akt_AKT1_ST	P07550	ADRB2	P31749	AKT1	S262	R259C	259	Missense	distal	-3	no	12.766	6.593	EPSD	GDSC;CCLE	7.780	Loss
AGC_Akt_AKT1_ST	P07550	ADRB2	P31749	AKT1	S407	G403R	403	Missense	distal	-4	no	13.355	14.169	EPSD	GDSC;CCLE	7.780	Up-regulation
AGC_Akt_AKT1_ST	P54578	USP14	P31749	AKT1	S230	A234G	234	Missense	distal	4	no	8.882	8.932	EPSD	GDSC	7.780	Up-regulation
AGC_Akt_AKT1_ST	P54578	USP14	P31749	AKT1	S230	S229L	229	Missense	proximal	-1	no	8.882	8.854	EPSD	GDSC;CCLE	7.780	Down-regulation
AGC_Akt_AKT1_ST	P54578	USP14	P31749	AKT1	S432	V437A	437	Missense	distal	5	no	13.126	13.134	PhosphoSitePlus	GDSC;CCLE	7.780	Up-regulation
AGC_Akt_AKT1_ST	P54578	USP14	P31749	AKT1	S432	S438P	438	Missense	distal	6	no	13.126	13.032	PhosphoSitePlus	GDSC;CCLE	7.780	Down-regulation
AGC_Akt_AKT1_ST	Q9H4A3	WNK1	P31749	AKT1	S167	L171F	171	Missense	distal	4	no	12.586	12.594	EPSD	GDSC;CCLE	7.780	Up-regulation
AGC_Akt_AKT1_ST	Q9NPC1	LTB4R2	P31749	AKT1	T336	P332R	332	Missense	distal	-4	no	10.072	10.894	EPSD	GDSC;CCLE	7.780	Up-regulation
AGC_Akt_AKT1_ST	P21333	FLNA	P31749	AKT1	S343	P348L	348	Missense	distal	5	no	14.230	14.216	EPSD	GDSC;CCLE	7.780	Down-regulation
AGC_Akt_AKT1_ST	P21333	FLNA	P31749	AKT1	S343	R340H	340	Missense	distal	-3	no	14.230	9.531	EPSD	GDSC	7.780	Down-regulation
AGC_Akt_AKT1_ST	P21333	FLNA	P31749	AKT1	S440	Q447*	447	Missense	distal	7	no	11.952	11.832	EPSD	GDSC	7.780	Down-regulation
AGC_Akt_AKT1_ST	P21333	FLNA	P31749	AKT1	T1275	S1279N	1279	Missense	distal	4	no	11.002	11.112	EPSD	GDSC;CCLE	7.780	Up-regulation
AGC_Akt_AKT1_ST	P21333	FLNA	P31749	AKT1	T1286	S1279N	1279	Missense	distal	-7	no	12.037	11.923	EPSD	GDSC;CCLE	7.780	Down-regulation
AGC_Akt_AKT1_ST	P21333	FLNA	P31749	AKT1	T1286	R1283Q	1283	Missense	distal	-3	no	12.037	4.826	EPSD	GDSC;CCLE	7.780	Loss
AGC_Akt_AKT1_ST	P21333	FLNA	P31749	AKT1	T1288	R1283Q	1283	Missense	distal	-5	no	8.034	3.806	EPSD	GDSC;CCLE	7.780	Loss
AGC_Akt_AKT1_ST	P21333	FLNA	P31749	AKT1	S1812	A1816V	1816	Missense	distal	4	no	9.361	9.417	EPSD	GDSC;CCLE	7.780	Up-regulation
AGC_Akt_AKT1_ST	P21333	FLNA	P31749	AKT1	S1812	R1809Q	1809	Missense	distal	-3	no	9.361	2.150	EPSD	GDSC;CCLE	7.780	Loss
AGC_Akt_AKT1_ST	P21333	FLNA	P31749	AKT1	T2336	R2334C	2334	Missense	proximal	-2	no	12.361	10.897	EPSD	GDSC	7.780	Down-regulation
AGC_Akt_AKT1_ST	P21333	FLNA	P31749	AKT1	S2338	R2334C	2334	Missense	distal	-4	no	9.813	8.134	EPSD	GDSC	7.780	Down-regulation
AGC_Akt_AKT1_ST	P30291	WEE1	P31749	AKT1	T257	R256S	256	Missense	proximal	-1	no	14.609	14.598	EPSD	GDSC;CCLE	7.780	Down-regulation
AGC_Akt_AKT1_ST	P41279	MAP3K8	P31749	AKT1	S400	L401R	401	Missense	proximal	1	no	11.067	11.113	PhosphoSitePlus	GDSC;CCLE	7.780	Up-regulation
AGC_Akt_AKT1_ST	Q96QB1	DLC1	P31749	AKT1	S306	Q303R	303	Missense	distal	-3	no	3.307	10.518	EPSD	GDSC;CCLE	7.780	Gain
AGC_Akt_AKT1_ST	Q96QB1	DLC1	P31749	AKT1	S354	R347*	347	Missense	distal	-7	no	14.062	13.285	EPSD	GDSC	7.780	Down-regulation
AGC_Akt_AKT1_ST	Q96QB1	DLC1	P31749	AKT1	S620	I622V	622	Missense	proximal	2	no	11.667	11.786	EPSD	GDSC;CCLE	7.780	Up-regulation
AGC_Akt_AKT1_ST	Q96QB1	DLC1	P31749	AKT1	S733	N736S	736	Missense	distal	3	no	10.316	10.372	EPSD	GDSC;CCLE	7.780	Up-regulation
AGC_Akt_AKT1_ST	Q96QB1	DLC1	P31749	AKT1	S735	N736S	736	Missense	proximal	1	no	16.477	16.565	PhosphoSitePlus;EPSD	GDSC;CCLE	7.780	Up-regulation
AGC_Akt_AKT1_ST	Q96QB1	DLC1	P31749	AKT1	S737	N736S	736	Missense	proximal	-1	no	10.749	10.767	EPSD	GDSC;CCLE	7.780	Up-regulation
AGC_Akt_AKT1_ST	Q96QB1	DLC1	P31749	AKT1	S764	V759F	759	Missense	distal	-5	no	12.778	13.571	EPSD	GDSC;CCLE	7.780	Up-regulation
AGC_Akt_AKT1_ST	Q96QB1	DLC1	P31749	AKT1	S842	F843L	843	Missense	proximal	1	no	9.815	9.896	EPSD	GDSC;CCLE	7.780	Up-regulation
AGC_Akt_AKT1_ST	Q96QB1	DLC1	P31749	AKT1	S856	N855S	855	Missense	proximal	-1	no	11.907	11.925	EPSD	GDSC;CCLE	7.780	Up-regulation
AGC_Akt_AKT1_ST	Q96QB1	DLC1	P31749	AKT1	S857	N855S	855	Missense	proximal	-2	no	9.035	9.721	EPSD	GDSC;CCLE	7.780	Up-regulation
AGC_Akt_AKT1_ST	Q96QB1	DLC1	P31749	AKT1	S1015	S1012I	1012	Missense	distal	-3	no	7.777	8.472	EPSD	GDSC;CCLE	7.780	Gain
AGC_Akt_AKT1_ST	Q96QB1	DLC1	P31749	AKT1	S1516	V1509I	1509	Missense	distal	-7	no	9.256	9.162	EPSD	GDSC	7.780	Down-regulation
AGC_Akt_AKT1_ST	Q96QB1	DLC1	P31749	AKT1	S1516	R1512W	1512	Missense	distal	-4	no	9.256	7.707	EPSD	GDSC;CCLE	7.780	Loss
AGC_Akt_AKT1_ST	P55072	VCP	P31749	AKT1	T316	P311L	311	Missense	distal	-5	no	12.127	12.011	EPSD	GDSC;CCLE	7.780	Down-regulation
AGC_Akt_AKT1_ST	Q92793	CREBBP	P31749	AKT1	S381	G375*	375	Missense	distal	-6	no	11.446	11.272	EPSD	GDSC	7.780	Down-regulation
AGC_Akt_AKT1_ST	Q92793	CREBBP	P31749	AKT1	S381	M388I	388	Missense	distal	7	no	11.446	11.408	EPSD	GDSC;CCLE	7.780	Down-regulation
AGC_Akt_AKT1_ST	Q92793	CREBBP	P31749	AKT1	S745	G740E	740	Missense	distal	-5	no	12.849	12.819	EPSD	GDSC;CCLE	7.780	Down-regulation
AGC_Akt_AKT1_ST	Q92793	CREBBP	P31749	AKT1	S1568	T1574A	1574	Missense	distal	6	no	11.882	11.779	EPSD	GDSC;CCLE	7.780	Down-regulation
AGC_Akt_AKT1_ST	Q92793	CREBBP	P31749	AKT1	S1568	E1573A	1573	Missense	distal	5	no	11.882	11.864	EPSD	GDSC;CCLE	7.780	Down-regulation
AGC_Akt_AKT1_ST	Q92793	CREBBP	P31749	AKT1	S1767	S1761*	1761	Missense	distal	-6	no	7.818	7.564	EPSD	GDSC	7.780	Loss
AGC_Akt_AKT1_ST	Q92793	CREBBP	P31749	AKT1	S1767	R1769P	1769	Missense	proximal	2	no	7.818	7.654	EPSD	GDSC	7.780	Loss
AGC_Akt_AKT1_ST	Q92793	CREBBP	P31749	AKT1	S1771	I1776M	1776	Missense	distal	5	no	12.661	12.701	EPSD	GDSC;CCLE	7.780	Up-regulation
AGC_Akt_AKT1_ST	Q92793	CREBBP	P31749	AKT1	S1771	R1769P	1769	Missense	proximal	-2	no	12.661	12.026	EPSD	GDSC	7.780	Down-regulation
AGC_Akt_AKT1_ST	P08670	VIM	P31749	AKT1	S278	A281T	281	Missense	distal	3	no	8.023	8.080	EPSD	GDSC;CCLE	7.780	Up-regulation
AGC_Akt_AKT1_ST	P08670	VIM	P31749	AKT1	S278	R273C	273	Missense	distal	-5	no	8.023	3.946	EPSD	GDSC;CCLE	7.780	Loss
AGC_Akt_AKT1_ST	P08670	VIM	P31749	AKT1	S325	A332V	332	Missense	distal	7	no	7.881	7.877	EPSD	GDSC;CCLE	7.780	Down-regulation
AGC_Akt_AKT1_ST	Q16763	UBE2S	P31749	AKT1	T152	R149H	149	Missense	distal	-3	no	13.745	9.046	PhosphoSitePlus	GDSC;CCLE	7.780	Down-regulation
AGC_Akt_AKT1_ST	Q96F86	EDC3	P31749	AKT1	S125	A129T	129	Missense	distal	4	no	8.609	8.480	EPSD	GDSC	7.780	Down-regulation
AGC_Akt_AKT1_ST	Q96F86	EDC3	P31749	AKT1	S233	R232G	232	Missense	proximal	-1	no	11.116	11.076	EPSD	GDSC;CCLE	7.780	Down-regulation
AGC_Akt_AKT1_ST	P14598	NCF1	P31749	AKT1	T45	H51L	51	Missense	distal	6	no	11.183	11.200	EPSD	GDSC	7.780	Up-regulation
AGC_Akt_AKT1_ST	P14598	NCF1	P31749	AKT1	T45	V40G	40	Missense	distal	-5	no	11.183	11.433	EPSD	GDSC	7.780	Up-regulation
AGC_Akt_AKT1_ST	P14598	NCF1	P31749	AKT1	T93	Q91K	91	Missense	proximal	-2	no	12.081	13.033	EPSD	GDSC;CCLE	7.780	Up-regulation
AGC_Akt_AKT1_ST	P14598	NCF1	P31749	AKT1	T95	Q91K	91	Missense	distal	-4	no	9.024	9.632	EPSD	GDSC;CCLE	7.780	Up-regulation
AGC_Akt_AKT1_ST	P14598	NCF1	P31749	AKT1	S328	Y324H	324	Missense	distal	-4	no	11.919	11.806	PhosphoSitePlus;EPSD	GDSC;CCLE	7.780	Down-regulation
AGC_Akt_AKT1_ST	P05455	SSB	P31749	AKT1	S366	H373N	373	Missense	distal	7	no	8.048	8.077	EPSD	GDSC	7.780	Up-regulation
AGC_Akt_AKT1_ST	P05455	SSB	P31749	AKT1	S366	D371G	371	Missense	distal	5	no	8.048	8.060	EPSD	GDSC;CCLE	7.780	Up-regulation
AGC_Akt_AKT1_ST	P29401	TKT	P31749	AKT1	S406	S408N	408	Missense	proximal	2	no	8.598	8.329	EPSD	GDSC	7.780	Down-regulation
AGC_Akt_AKT1_ST	O15360	FANCA	P31749	AKT1	S347	R350W	350	Missense	distal	3	no	10.908	10.796	EPSD	GDSC;CCLE	7.780	Down-regulation
AGC_Akt_AKT1_ST	Q9BPZ7	MAPKAP1	P31749	AKT1	S315	R311*	311	Missense	distal	-4	no	13.816	11.086	EPSD	GDSC	7.780	Down-regulation
AGC_Akt_AKT1_ST	Q9BPZ7	MAPKAP1	P31749	AKT1	S315	K317N	317	Missense	proximal	2	no	13.816	13.531	EPSD	GDSC;CCLE	7.780	Down-regulation
AGC_Akt_AKT1_ST	P53602	MVD	P31749	AKT1	S156	A159S	159	Missense	distal	3	no	11.774	11.832	EPSD	GDSC;CCLE	7.780	Up-regulation
AGC_Akt_AKT1_ST	P53602	MVD	P31749	AKT1	S156	G157D	157	Missense	proximal	1	no	11.774	11.866	EPSD	GDSC;CCLE	7.780	Up-regulation
AGC_Akt_AKT1_ST	P53602	MVD	P31749	AKT1	S156	R161W	161	Missense	distal	5	no	11.774	11.680	EPSD	GDSC	7.780	Down-regulation
AGC_Akt_AKT1_ST	P53602	MVD	P31749	AKT1	S156	R153L	153	Missense	distal	-3	no	11.774	4.780	EPSD	GDSC	7.780	Loss
AGC_Akt_AKT1_ST	P53602	MVD	P31749	AKT1	S158	A159S	159	Missense	proximal	1	no	8.711	8.784	EPSD	GDSC;CCLE	7.780	Up-regulation
AGC_Akt_AKT1_ST	P53602	MVD	P31749	AKT1	S158	G157D	157	Missense	proximal	-1	no	8.711	8.692	EPSD	GDSC;CCLE	7.780	Down-regulation
AGC_Akt_AKT1_ST	P53602	MVD	P31749	AKT1	S158	R161W	161	Missense	distal	3	no	8.711	8.599	EPSD	GDSC	7.780	Down-regulation
AGC_Akt_AKT1_ST	P53602	MVD	P31749	AKT1	S158	R153L	153	Missense	distal	-5	no	8.711	4.584	EPSD	GDSC	7.780	Loss
AGC_Akt_AKT1_ST	Q9UNN5	FAF1	P31749	AKT1	S270	R275W	275	Missense	distal	5	no	13.035	12.941	EPSD	GDSC	7.780	Down-regulation
AGC_Akt_AKT1_ST	Q99623	PHB2	P31749	AKT1	S91	G95V	95	Missense	distal	4	no	16.515	16.522	PhosphoSitePlus;EPSD	GDSC;CCLE	7.780	Up-regulation
AGC_Akt_AKT1_ST	Q99623	PHB2	P31749	AKT1	T194	R191Q	191	Missense	distal	-3	no	10.881	3.670	EPSD	GDSC	7.780	Loss
AGC_Akt_AKT1_ST	Q99623	PHB2	P31749	AKT1	T194	Q201P	201	Missense	distal	7	no	10.881	10.871	EPSD	GDSC;CCLE	7.780	Down-regulation
AGC_Akt_AKT1_ST	Q9UBP6	METTL1	P31749	AKT1	S27	Y20*	20	Missense	distal	-7	no	16.706	16.191	PhosphoSitePlus	GDSC	7.780	Down-regulation
AGC_Akt_AKT1_ST	P17302	GJA1	P31749	AKT1	S296	G291D	291	Missense	distal	-5	no	9.909	9.928	EPSD	GDSC;CCLE	7.780	Up-regulation
AGC_Akt_AKT1_ST	P17302	GJA1	P31749	AKT1	S296	R299C	299	Missense	distal	3	no	9.909	9.748	EPSD	GDSC;CCLE	7.780	Down-regulation
AGC_Akt_AKT1_ST	P17302	GJA1	P31749	AKT1	S296	V289G	289	Missense	distal	-7	no	9.909	10.000	EPSD	GDSC;CCLE	7.780	Up-regulation
AGC_Akt_AKT1_ST	P17302	GJA1	P31749	AKT1	S296	D292G	292	Missense	distal	-4	no	9.909	10.468	EPSD	GDSC;CCLE	7.780	Up-regulation
AGC_Akt_AKT1_ST	P06748	NPM1	P31749	AKT1	S43	N38D	38	Missense	distal	-5	no	7.594	8.033	EPSD	GDSC;CCLE	7.780	Gain
AGC_Akt_AKT1_ST	Q92945	KHSRP	P31749	AKT1	S193	R190H	190	Missense	distal	-3	no	13.425	8.726	PhosphoSitePlus	GDSC;CCLE	7.780	Down-regulation
AGC_Akt_AKT1_ST	Q92945	KHSRP	P31749	AKT1	S193	E199*	199	Missense	distal	6	no	13.425	13.193	PhosphoSitePlus	GDSC	7.780	Down-regulation
AGC_Akt_AKT1_ST	Q92945	KHSRP	P31749	AKT1	T195	Q202*	202	Missense	distal	7	no	10.007	9.887	EPSD	GDSC	7.780	Down-regulation
AGC_Akt_AKT1_ST	Q92945	KHSRP	P31749	AKT1	T195	R190H	190	Missense	distal	-5	no	10.007	6.912	EPSD	GDSC;CCLE	7.780	Loss
AGC_Akt_AKT1_ST	Q92945	KHSRP	P31749	AKT1	T195	E199*	199	Missense	distal	4	no	10.007	10.360	EPSD	GDSC	7.780	Up-regulation
AGC_Akt_AKT1_ST	O60331	PIP5K1C	P31749	AKT1	T135	Q129R	129	Missense	distal	-6	no	9.425	9.509	EPSD	GDSC;CCLE	7.780	Up-regulation
AGC_Akt_AKT1_ST	O60331	PIP5K1C	P31749	AKT1	T135	Q129*	129	Missense	distal	-6	no	9.425	9.222	EPSD	GDSC	7.780	Down-regulation
AGC_Akt_AKT1_ST	O60331	PIP5K1C	P31749	AKT1	S541	T543M	543	Missense	proximal	2	no	11.411	11.069	EPSD	GDSC	7.780	Down-regulation
AGC_Akt_AKT1_ST	O60331	PIP5K1C	P31749	AKT1	T543	T543M	543	Missense	central	0	yes	10.500	0.000	EPSD	GDSC	7.780	Loss
AGC_Akt_AKT1_ST	O60331	PIP5K1C	P31749	AKT1	T543	R550G	550	Missense	distal	7	no	10.500	10.419	EPSD	GDSC	7.780	Down-regulation
AGC_Akt_AKT1_ST	O60331	PIP5K1C	P31749	AKT1	T553	R550G	550	Missense	distal	-3	no	14.941	8.185	EPSD	GDSC	7.780	Down-regulation
AGC_Akt_AKT1_ST	O60331	PIP5K1C	P31749	AKT1	S555	R550G	550	Missense	distal	-5	no	16.291	12.227	PhosphoSitePlus	GDSC	7.780	Down-regulation
AGC_Akt_AKT1_ST	O60331	PIP5K1C	P31749	AKT1	S556	R550G	550	Missense	distal	-6	no	8.805	8.691	EPSD	GDSC	7.780	Down-regulation
AGC_Akt_AKT1_ST	Q12906	ILF3	P31749	AKT1	S384	S384N	384	Missense	central	0	yes	8.205	0.000	EPSD	GDSC;CCLE	7.780	Loss
AGC_Akt_AKT1_ST	Q12906	ILF3	P31749	AKT1	S647	R653Q	653	Missense	distal	6	no	16.183	16.112	PhosphoSitePlus	GDSC	7.780	Down-regulation
AGC_Akt_AKT1_ST	Q8WYL5	SSH1	P31749	AKT1	S237	A239T	239	Missense	proximal	2	no	10.340	10.641	EPSD	GDSC;CCLE	7.780	Up-regulation
AGC_Akt_AKT1_ST	P35222	CTNNB1	P31749	AKT1	S129	A135V	135	Missense	distal	6	no	8.080	8.048	EPSD	GDSC;CCLE	7.780	Down-regulation
AGC_Akt_AKT1_ST	P35222	CTNNB1	P31749	AKT1	T547	R549H	549	Missense	proximal	2	no	9.356	8.995	EPSD	GDSC;CCLE	7.780	Down-regulation
AGC_Akt_AKT1_ST	P35222	CTNNB1	P31749	AKT1	S552	R549H	549	Missense	distal	-3	no	12.531	7.832	PhosphoSitePlus	GDSC;CCLE	7.780	Down-regulation
AGC_Akt_AKT1_ST	P35222	CTNNB1	P31749	AKT1	S675	Y670*	670	Missense	distal	-5	no	7.903	1.751	EPSD	GDSC	7.780	Loss
AGC_Akt_AKT1_ST	P54274	TERF1	P31749	AKT1	T24	D17G	17	Missense	distal	-7	no	7.866	8.051	EPSD	GDSC	7.780	Up-regulation
AGC_Akt_AKT1_ST	P54274	TERF1	P31749	AKT1	T24	R19K	19	Missense	distal	-5	no	7.866	5.469	EPSD	GDSC;CCLE	7.780	Loss
AGC_Akt_AKT1_ST	Q99490	AGAP2	P31749	AKT1	S226	G223R	223	Missense	distal	-3	no	6.435	13.191	EPSD	GDSC;CCLE	7.780	Gain
AGC_Akt_AKT1_ST	Q99490	AGAP2	P31749	AKT1	S523	R525G	525	Missense	proximal	2	no	8.050	7.890	EPSD	GDSC;CCLE	7.780	Down-regulation
AGC_Akt_AKT1_ST	O14746	TERT	P31749	AKT1	T618	A615V	615	Missense	distal	-3	no	8.229	7.667	EPSD	GDSC;CCLE	7.780	Loss
AGC_Akt_AKT1_ST	P21453	S1PR1	P31749	AKT1	T236	R229S	229	Missense	distal	-7	no	16.477	16.421	PhosphoSitePlus	GDSC;CCLE	7.780	Down-regulation
AGC_Akt_AKT1_ST	P21453	S1PR1	P31749	AKT1	S355	P361T	361	Missense	distal	6	no	13.849	13.963	EPSD	GDSC;CCLE	7.780	Up-regulation
AGC_Akt_AKT1_ST	P46937	YAP1	P31749	AKT1	S94	P98L	98	Missense	distal	4	no	8.520	8.553	EPSD	GDSC;CCLE	7.780	Up-regulation
AGC_Akt_AKT1_ST	P46937	YAP1	P31749	AKT1	S105	P98L	98	Missense	distal	-7	no	8.034	7.994	EPSD	GDSC;CCLE	7.780	Down-regulation
AGC_Akt_AKT1_ST	P46937	YAP1	P31749	AKT1	S164	R161*	161	Missense	distal	-3	no	11.562	-5.827	EPSD	GDSC	7.780	Loss
AGC_Akt_AKT1_ST	P46937	YAP1	P31749	AKT1	S257	T255N	255	Missense	proximal	-2	no	9.146	8.526	EPSD	GDSC	7.780	Down-regulation
AGC_Akt_AKT1_ST	P46937	YAP1	P31749	AKT1	T378	D383A	383	Missense	distal	5	no	9.656	9.680	EPSD	GDSC;CCLE	7.780	Up-regulation
AGC_Akt_AKT1_ST	P46937	YAP1	P31749	AKT1	S499	S499G	499	Missense	central	0	yes	9.760	0.000	EPSD	GDSC;CCLE	7.780	Loss
AGC_Akt_AKT1_ST	Q9H9Q4	NHEJ1	P31749	AKT1	T181	T181K	181	Missense	central	0	yes	13.742	0.000	PhosphoSitePlus	GDSC;CCLE	7.780	Loss
AGC_Akt_AKT1_ST	Q9H9Q4	NHEJ1	P31749	AKT1	T181	L174P	174	Missense	distal	-7	no	13.742	13.782	PhosphoSitePlus	GDSC;CCLE	7.780	Up-regulation
AGC_Akt_AKT1_ST	Q9NWV8	BABAM1	P31749	AKT1	T27	R28C	28	Missense	proximal	1	no	11.107	10.579	EPSD	GDSC;CCLE	7.780	Down-regulation
AGC_Akt_AKT1_ST	Q9NWV8	BABAM1	P31749	AKT1	T27	R24L	24	Missense	distal	-3	no	11.107	4.114	EPSD	GDSC;CCLE	7.780	Loss
AGC_Akt_AKT1_ST	Q9NWV8	BABAM1	P31749	AKT1	S29	R28C	28	Missense	proximal	-1	no	15.557	15.486	PhosphoSitePlus	GDSC;CCLE	7.780	Down-regulation
AGC_Akt_AKT1_ST	Q9NWV8	BABAM1	P31749	AKT1	S29	R24L	24	Missense	distal	-5	no	15.557	11.430	PhosphoSitePlus	GDSC;CCLE	7.780	Down-regulation
AGC_Akt_AKT1_ST	Q86TI0	TBC1D1	P31749	AKT1	T294	R289*	289	Missense	distal	-5	no	8.234	-2.526	EPSD	GDSC	7.780	Loss
AGC_Akt_AKT1_ST	Q86TI0	TBC1D1	P31749	AKT1	T505	L504V	504	Missense	proximal	-1	no	12.351	12.344	EPSD	GDSC	7.780	Down-regulation
AGC_Akt_AKT1_ST	Q86TI0	TBC1D1	P31749	AKT1	T505	K499E	499	Missense	distal	-6	no	12.351	12.284	EPSD	GDSC	7.780	Down-regulation
AGC_Akt_AKT1_ST	Q86TI0	TBC1D1	P31749	AKT1	S507	L504V	504	Missense	distal	-3	no	9.996	10.125	EPSD	GDSC	7.780	Up-regulation
AGC_Akt_AKT1_ST	Q86TI0	TBC1D1	P31749	AKT1	S527	S532C	532	Missense	distal	5	no	7.920	7.802	EPSD	GDSC;CCLE	7.780	Down-regulation
AGC_Akt_AKT1_ST	Q86TI0	TBC1D1	P31749	AKT1	S660	R657G	657	Missense	distal	-3	no	15.256	8.500	EPSD	GDSC	7.780	Down-regulation
AGC_Akt_AKT1_ST	Q86TI0	TBC1D1	P31749	AKT1	S1154	T1161M	1161	Missense	distal	7	no	11.797	11.728	EPSD	GDSC	7.780	Down-regulation
AGC_Akt_AKT1_ST	Q9Y2I7	PIKFYVE	P31749	AKT1	T22	P21A	21	Missense	proximal	-1	no	10.847	10.855	EPSD	GDSC;CCLE	7.780	Up-regulation
AGC_Akt_AKT1_ST	Q9Y2I7	PIKFYVE	P31749	AKT1	S85	S88P	88	Missense	distal	3	no	12.329	12.248	EPSD	GDSC;CCLE	7.780	Down-regulation
AGC_Akt_AKT1_ST	Q9Y2I7	PIKFYVE	P31749	AKT1	T90	S88P	88	Missense	proximal	-2	no	9.944	9.120	EPSD	GDSC;CCLE	7.780	Down-regulation
AGC_Akt_AKT1_ST	Q9Y2I7	PIKFYVE	P31749	AKT1	S105	A106V	106	Missense	proximal	1	no	10.955	11.027	EPSD	GDSC;CCLE	7.780	Up-regulation
AGC_Akt_AKT1_ST	Q9Y2I7	PIKFYVE	P31749	AKT1	S291	Q293P	293	Missense	proximal	2	no	11.762	11.715	EPSD	GDSC;CCLE	7.780	Down-regulation
AGC_Akt_AKT1_ST	Q9Y2I7	PIKFYVE	P31749	AKT1	T341	V337F	337	Missense	distal	-4	no	9.937	9.863	EPSD	GDSC;CCLE	7.780	Down-regulation
AGC_Akt_AKT1_ST	Q9Y2I7	PIKFYVE	P31749	AKT1	S1440	K1446E	1446	Missense	distal	6	no	7.968	7.898	EPSD	GDSC;CCLE	7.780	Down-regulation
AGC_Akt_AKT1_ST	Q9Y2I7	PIKFYVE	P31749	AKT1	S1474	S1474F	1474	Missense	central	0	yes	12.258	0.000	EPSD	GDSC;CCLE	7.780	Loss
AGC_Akt_AKT1_ST	Q9Y2I7	PIKFYVE	P31749	AKT1	S1549	R1546L	1546	Missense	distal	-3	no	8.626	1.633	EPSD	GDSC;CCLE	7.780	Loss
AGC_Akt_AKT1_ST	Q6R327	RICTOR	P31749	AKT1	S35	R32L	32	Missense	distal	-3	no	10.036	3.042	EPSD	GDSC;CCLE	7.780	Loss
AGC_Akt_AKT1_ST	Q6R327	RICTOR	P31749	AKT1	S1035	H1033Y	1033	Missense	proximal	-2	no	11.352	11.480	EPSD	GDSC	7.780	Up-regulation
AGC_Akt_AKT1_ST	Q6R327	RICTOR	P31749	AKT1	S1037	H1033Y	1033	Missense	distal	-4	no	9.015	9.129	EPSD	GDSC	7.780	Up-regulation
AGC_Akt_AKT1_ST	Q6R327	RICTOR	P31749	AKT1	S1302	A1300T	1300	Missense	proximal	-2	no	13.316	13.702	EPSD	GDSC;CCLE	7.780	Up-regulation
AGC_Akt_AKT1_ST	Q6R327	RICTOR	P31749	AKT1	S1408	R1405*	1405	Missense	distal	-3	no	14.254	-3.135	EPSD	GDSC	7.780	Loss
AGC_Akt_AKT1_ST	P45985	MAP2K4	P31749	AKT1	T78	S80I	80	Missense	proximal	2	no	10.970	10.314	EPSD	GDSC;CCLE	7.780	Down-regulation
AGC_Akt_AKT1_ST	P45985	MAP2K4	P31749	AKT1	S80	S80I	80	Missense	central	0	yes	16.956	0.000	PhosphoSitePlus	GDSC;CCLE	7.780	Loss
AGC_Akt_AKT1_ST	P45985	MAP2K4	P31749	AKT1	S292	W291*	291	Missense	proximal	-1	no	9.191	9.152	EPSD	GDSC	7.780	Down-regulation
AGC_Akt_AKT1_ST	Q96CG3	TIFA	P31749	AKT1	S171	L168F	168	Missense	distal	-3	no	6.523	7.923	EPSD	GDSC	7.780	Gain
AGC_Akt_AKT1_ST	Q96CG3	TIFA	P31749	AKT1	S174	P176L	176	Missense	proximal	2	no	8.143	7.933	EPSD	GDSC	7.780	Down-regulation
AGC_Akt_AKT1_ST	Q96CG3	TIFA	P31749	AKT1	S174	L168F	168	Missense	distal	-6	no	8.143	8.119	EPSD	GDSC	7.780	Down-regulation
AGC_Akt_AKT1_ST	Q96CG3	TIFA	P31749	AKT1	S175	P176L	176	Missense	proximal	1	no	7.812	8.066	EPSD	GDSC	7.780	Up-regulation
AGC_Akt_AKT1_ST	Q96CG3	TIFA	P31749	AKT1	S175	L168F	168	Missense	distal	-7	no	7.812	7.768	EPSD	GDSC	7.780	Loss
AGC_Akt_AKT1_ST	Q8WX93	PALLD	P31749	AKT1	S125	S118*	118	Missense	distal	-7	no	8.726	8.005	EPSD	GDSC	7.780	Down-regulation
AGC_Akt_AKT1_ST	Q8WX93	PALLD	P31749	AKT1	S192	P193L	193	Missense	proximal	1	no	12.748	13.002	EPSD	GDSC;CCLE	7.780	Up-regulation
AGC_Akt_AKT1_ST	Q8WX93	PALLD	P31749	AKT1	S192	S199P	199	Missense	distal	7	no	12.748	12.690	EPSD	GDSC;CCLE	7.780	Down-regulation
AGC_Akt_AKT1_ST	Q8WX93	PALLD	P31749	AKT1	S356	D353G	353	Missense	distal	-3	no	7.847	7.042	EPSD	GDSC;CCLE	7.780	Loss
AGC_Akt_AKT1_ST	Q8WX93	PALLD	P31749	AKT1	S479	D486Y	486	Missense	distal	7	no	8.089	8.123	EPSD	GDSC;CCLE	7.780	Up-regulation
AGC_Akt_AKT1_ST	Q8WX93	PALLD	P31749	AKT1	S582	Q586*	586	Missense	distal	4	no	7.694	7.992	EPSD	GDSC	7.780	Gain
AGC_Akt_AKT1_ST	Q7Z6J0	SH3RF1	P31749	AKT1	S58	G59V	59	Missense	proximal	1	no	8.450	8.754	EPSD	GDSC	7.780	Up-regulation
AGC_Akt_AKT1_ST	Q7Z6J0	SH3RF1	P31749	AKT1	S125	W126*	126	Missense	proximal	1	no	10.727	10.371	EPSD	GDSC	7.780	Down-regulation
AGC_Akt_AKT1_ST	Q7Z6J0	SH3RF1	P31749	AKT1	S125	V123M	123	Missense	proximal	-2	no	10.727	11.077	EPSD	GDSC;CCLE	7.780	Up-regulation
AGC_Akt_AKT1_ST	Q7Z6J0	SH3RF1	P31749	AKT1	S304	S304F	304	Missense	central	0	yes	10.102	0.000	PhosphoSitePlus	GDSC;CCLE	7.780	Loss
AGC_Akt_AKT1_ST	Q7Z6J0	SH3RF1	P31749	AKT1	S304	R302Q	302	Missense	proximal	-2	no	10.102	9.590	PhosphoSitePlus	GDSC	7.780	Down-regulation
AGC_Akt_AKT1_ST	Q7Z6J0	SH3RF1	P31749	AKT1	T306	S304F	304	Missense	proximal	-2	no	8.492	7.626	EPSD	GDSC;CCLE	7.780	Loss
AGC_Akt_AKT1_ST	Q7Z6J0	SH3RF1	P31749	AKT1	T306	R302Q	302	Missense	distal	-4	no	8.492	7.871	EPSD	GDSC	7.780	Down-regulation
AGC_Akt_AKT1_ST	Q7Z6J0	SH3RF1	P31749	AKT1	S307	S304F	304	Missense	distal	-3	no	7.176	9.358	EPSD	GDSC;CCLE	7.780	Gain
AGC_Akt_AKT1_ST	Q7Z6J0	SH3RF1	P31749	AKT1	T529	M530T	530	Missense	proximal	1	no	11.455	11.711	EPSD	GDSC;CCLE	7.780	Up-regulation
AGC_Akt_AKT1_ST	Q7Z6J0	SH3RF1	P31749	AKT1	S735	K731R	731	Missense	distal	-4	no	10.577	10.590	EPSD	GDSC	7.780	Up-regulation
AGC_Akt_AKT1_ST	Q7Z6J0	SH3RF1	P31749	AKT1	S772	G779R	779	Missense	distal	7	no	12.049	12.129	EPSD	GDSC;CCLE	7.780	Up-regulation
AGC_Akt_AKT1_ST	Q7Z6J0	SH3RF1	P31749	AKT1	T782	G779R	779	Missense	distal	-3	no	2.821	9.577	EPSD	GDSC;CCLE	7.780	Gain
AGC_Akt_AKT1_ST	Q8NCD3	HJURP	P31749	AKT1	T380	V379L	379	Missense	proximal	-1	no	12.598	12.605	EPSD	GDSC;CCLE	7.780	Up-regulation
AGC_Akt_AKT1_ST	Q8NCD3	HJURP	P31749	AKT1	S382	V379L	379	Missense	distal	-3	no	10.087	9.958	EPSD	GDSC;CCLE	7.780	Down-regulation
AGC_Akt_AKT1_ST	Q8NCD3	HJURP	P31749	AKT1	S448	H442Y	442	Missense	distal	-6	no	7.773	7.799	EPSD	GDSC;CCLE	7.780	Gain
AGC_Akt_AKT1_ST	Q8NCD3	HJURP	P31749	AKT1	S486	T482S	482	Missense	distal	-4	no	13.501	13.445	PhosphoSitePlus	GDSC;CCLE	7.780	Down-regulation
AGC_Akt_AKT1_ST	Q8NCD3	HJURP	P31749	AKT1	S489	T482S	482	Missense	distal	-7	no	8.222	8.172	EPSD	GDSC;CCLE	7.780	Down-regulation
AGC_Akt_AKT1_ST	P35568	IRS1	P31749	AKT1	S268	R267C	267	Missense	proximal	-1	no	11.282	11.211	EPSD	GDSC;CCLE	7.780	Down-regulation
AGC_Akt_AKT1_ST	P35568	IRS1	P31749	AKT1	S270	R267C	267	Missense	distal	-3	no	14.918	8.745	EPSD	GDSC;CCLE	7.780	Down-regulation
AGC_Akt_AKT1_ST	P35568	IRS1	P31749	AKT1	S272	R267C	267	Missense	distal	-5	no	12.914	8.838	EPSD	GDSC;CCLE	7.780	Down-regulation
AGC_Akt_AKT1_ST	P35568	IRS1	P31749	AKT1	S362	R364W	364	Missense	proximal	2	no	8.382	7.927	EPSD	GDSC	7.780	Down-regulation
AGC_Akt_AKT1_ST	P35568	IRS1	P31749	AKT1	S362	P368A	368	Missense	distal	6	no	8.382	8.393	EPSD	GDSC;CCLE	7.780	Up-regulation
AGC_Akt_AKT1_ST	P35568	IRS1	P31749	AKT1	S374	H371R	371	Missense	distal	-3	no	5.320	10.019	EPSD	GDSC	7.780	Gain
AGC_Akt_AKT1_ST	P35568	IRS1	P31749	AKT1	S413	R411*	411	Missense	proximal	-2	no	12.105	10.249	EPSD	GDSC	7.780	Down-regulation
AGC_Akt_AKT1_ST	P35568	IRS1	P31749	AKT1	S415	R411*	411	Missense	distal	-4	no	8.256	5.526	EPSD	GDSC	7.780	Loss
AGC_Akt_AKT1_ST	P35568	IRS1	P31749	AKT1	S603	G597E	597	Missense	distal	-6	no	12.032	12.065	EPSD	GDSC	7.780	Up-regulation
AGC_Akt_AKT1_ST	P35568	IRS1	P31749	AKT1	T859	R854C	854	Missense	distal	-5	no	8.975	4.898	EPSD	GDSC	7.780	Loss
AGC_Akt_AKT1_ST	P35568	IRS1	P31749	AKT1	S1084	S1084R	1084	Missense	central	0	yes	10.904	0.000	EPSD	GDSC	7.780	Loss
AGC_Akt_AKT1_ST	P35568	IRS1	P31749	AKT1	S1084	A1085D	1085	Missense	proximal	1	no	10.904	10.764	EPSD	GDSC;CCLE	7.780	Down-regulation
AGC_Akt_AKT1_ST	P35568	IRS1	P31749	AKT1	S1084	R1089G	1089	Missense	distal	5	no	10.904	10.834	EPSD	GDSC;CCLE	7.780	Down-regulation
AGC_Akt_AKT1_ST	P35568	IRS1	P31749	AKT1	S1100	R1096G	1096	Missense	distal	-4	no	13.515	12.700	EPSD	GDSC;CCLE	7.780	Down-regulation
AGC_Akt_AKT1_ST	P35568	IRS1	P31749	AKT1	S1101	R1096G	1096	Missense	distal	-5	no	16.825	12.761	EPSD	GDSC;CCLE	7.780	Down-regulation
AGC_Akt_AKT1_ST	P35568	IRS1	P31749	AKT1	T1103	R1096G	1096	Missense	distal	-7	no	7.892	7.650	EPSD	GDSC;CCLE	7.780	Loss
AGC_Akt_AKT1_ST	P35568	IRS1	P31749	AKT1	S1223	S1218P	1218	Missense	distal	-5	no	13.710	14.170	EPSD	GDSC	7.780	Up-regulation
AGC_Akt_AKT1_ST	P35568	IRS1	P31749	AKT1	S1231	S1233N	1233	Missense	proximal	2	no	8.367	8.098	EPSD	GDSC;CCLE	7.780	Down-regulation
AGC_Akt_AKT1_ST	Q16875	PFKFB3	P31749	AKT1	S478	R475H	475	Missense	distal	-3	no	13.716	9.018	EPSD	GDSC;CCLE	7.780	Down-regulation
AGC_Akt_AKT1_ST	P29317	EPHA2	P31749	AKT1	S897	P896R	896	Missense	proximal	-1	no	10.610	10.650	PhosphoSitePlus	GDSC;CCLE	7.780	Up-regulation
AGC_Akt_AKT1_ST	P29317	EPHA2	P31749	AKT1	S899	P896R	896	Missense	distal	-3	no	9.398	16.038	EPSD	GDSC;CCLE	7.780	Up-regulation
AGC_Akt_AKT1_ST	P29317	EPHA2	P31749	AKT1	S901	P896R	896	Missense	distal	-5	no	5.389	9.399	EPSD	GDSC;CCLE	7.780	Gain
AGC_Akt_AKT1_ST	P29317	EPHA2	P31749	AKT1	S961	A959T	959	Missense	proximal	-2	no	10.019	10.404	EPSD	GDSC	7.780	Up-regulation
AGC_Akt_AKT1_ST	O15519	CFLAR	P31749	AKT1	S273	E277K	277	Missense	distal	4	no	8.098	7.998	PhosphoSitePlus	GDSC;CCLE	7.780	Down-regulation
AGC_Akt_AKT1_ST	P26358	DNMT1	P31749	AKT1	T12	P7A	7	Missense	distal	-5	no	11.540	11.696	EPSD	GDSC;CCLE	7.780	Up-regulation
AGC_Akt_AKT1_ST	Q96KG9	SCYL1	P31749	AKT1	T469	T469P	469	Missense	central	0	yes	13.647	0.000	PhosphoSitePlus	GDSC	7.780	Loss
AGC_Akt_AKT1_ST	Q96KG9	SCYL1	P31749	AKT1	S723	W727*	727	Missense	distal	4	no	12.444	12.617	EPSD	GDSC	7.780	Up-regulation
AGC_Akt_AKT1_ST	P15976	GATA1	P31749	AKT1	S116	Q119*	119	Missense	distal	3	no	12.092	11.973	EPSD	GDSC	7.780	Down-regulation
AGC_Akt_AKT1_ST	Q99502	EYA1	P31749	AKT1	S299	S292C	292	Missense	distal	-7	no	16.579	16.156	PhosphoSitePlus	GDSC;CCLE	7.780	Down-regulation
AGC_Akt_AKT1_ST	Q99502	EYA1	P31749	AKT1	S299	R297L	297	Missense	proximal	-2	no	16.579	15.911	PhosphoSitePlus	GDSC;CCLE	7.780	Down-regulation
AGC_Akt_AKT1_ST	Q99502	EYA1	P31749	AKT1	S314	P315L	315	Missense	proximal	1	no	7.980	8.234	EPSD	GDSC;CCLE	7.780	Up-regulation
AGC_Akt_AKT1_ST	P17542	TAL1	P31749	AKT1	S7	P14H	14	Missense	distal	7	no	12.747	12.741	EPSD	GDSC;CCLE	7.780	Down-regulation
AGC_Akt_AKT1_ST	P17542	TAL1	P31749	AKT1	S316	A309S	309	Missense	distal	-7	no	8.110	8.259	EPSD	GDSC	7.780	Up-regulation
AGC_Akt_AKT1_ST	P17542	TAL1	P31749	AKT1	S316	T313A	313	Missense	distal	-3	no	8.110	8.829	EPSD	GDSC;CCLE	7.780	Up-regulation
AGC_Akt_AKT1_ST	Q92934	BAD	P31749	AKT1	S25	D29N	29	Missense	distal	4	no	8.979	8.864	EPSD	GDSC	7.780	Down-regulation
AGC_Akt_AKT1_ST	Q92934	BAD	P31749	AKT1	S134	T137K	137	Missense	distal	3	no	11.762	11.766	EPSD	GDSC	7.780	Up-regulation
AGC_Akt_AKT1_ST	Q92934	BAD	P31749	AKT1	S134	L129F	129	Missense	distal	-5	no	11.762	12.367	EPSD	GDSC	7.780	Up-regulation
AGC_Akt_AKT1_ST	Q92934	BAD	P31749	AKT1	S145	F151L	151	Missense	distal	6	no	9.942	9.958	EPSD	GDSC;CCLE	7.780	Up-regulation
AGC_Akt_AKT1_ST	Q92934	BAD	P31749	AKT1	S153	F151L	151	Missense	proximal	-2	no	8.003	8.013	EPSD	GDSC;CCLE	7.780	Up-regulation
AGC_Akt_AKT1_ST	P18031	PTPN1	P31749	AKT1	T224	G220V	220	Missense	distal	-4	no	9.882	9.518	EPSD	GDSC;CCLE	7.780	Down-regulation
AGC_Akt_AKT1_ST	P18031	PTPN1	P31749	AKT1	S378	V375M	375	Missense	distal	-3	no	8.454	7.813	EPSD	GDSC	7.780	Down-regulation
AGC_Akt_AKT1_ST	P18031	PTPN1	P31749	AKT1	S378	A382D	382	Missense	distal	4	no	8.454	8.554	EPSD	GDSC	7.780	Up-regulation
AGC_Akt_AKT1_ST	Q96HP0	DOCK6	P31749	AKT1	S40	V45I	45	Missense	distal	5	no	12.727	12.690	EPSD	GDSC	7.780	Down-regulation
AGC_Akt_AKT1_ST	Q96HP0	DOCK6	P31749	AKT1	S41	V45I	45	Missense	distal	4	no	9.585	9.666	EPSD	GDSC	7.780	Up-regulation
AGC_Akt_AKT1_ST	Q96HP0	DOCK6	P31749	AKT1	S42	V45I	45	Missense	distal	3	no	11.668	11.627	EPSD	GDSC	7.780	Down-regulation
AGC_Akt_AKT1_ST	Q96HP0	DOCK6	P31749	AKT1	S176	S169L	169	Missense	distal	-7	no	13.373	13.139	EPSD	GDSC	7.780	Down-regulation
AGC_Akt_AKT1_ST	Q96HP0	DOCK6	P31749	AKT1	S483	R487P	487	Missense	distal	4	no	12.700	12.845	EPSD	GDSC;CCLE	7.780	Up-regulation
AGC_Akt_AKT1_ST	Q96HP0	DOCK6	P31749	AKT1	S484	R487P	487	Missense	distal	3	no	11.184	11.119	EPSD	GDSC;CCLE	7.780	Down-regulation
AGC_Akt_AKT1_ST	Q96HP0	DOCK6	P31749	AKT1	T493	R487P	487	Missense	distal	-6	no	14.032	13.934	EPSD	GDSC;CCLE	7.780	Down-regulation
AGC_Akt_AKT1_ST	Q96HP0	DOCK6	P31749	AKT1	S880	S882N	882	Missense	proximal	2	no	12.286	12.017	EPSD	GDSC;CCLE	7.780	Down-regulation
AGC_Akt_AKT1_ST	Q96HP0	DOCK6	P31749	AKT1	S882	S882N	882	Missense	central	0	yes	11.961	0.000	EPSD	GDSC;CCLE	7.780	Loss
AGC_Akt_AKT1_ST	Q96HP0	DOCK6	P31749	AKT1	S1308	R1305H	1305	Missense	distal	-3	no	12.737	8.039	EPSD	GDSC;CCLE	7.780	Down-regulation
AGC_Akt_AKT1_ST	Q96HP0	DOCK6	P31749	AKT1	S1343	R1338*	1338	Missense	distal	-5	no	14.730	3.969	EPSD	GDSC	7.780	Loss
AGC_Akt_AKT1_ST	Q96HP0	DOCK6	P31749	AKT1	S2036	L2033F	2033	Missense	distal	-3	no	7.860	9.260	EPSD	GDSC	7.780	Up-regulation
AGC_Akt_AKT1_ST	P22736	NR4A1	P31749	AKT1	S23	T27I	27	Missense	distal	4	no	9.619	9.885	EPSD	GDSC;CCLE	7.780	Up-regulation
AGC_Akt_AKT1_ST	P22736	NR4A1	P31749	AKT1	S23	D24E	24	Missense	proximal	1	no	9.619	9.736	EPSD	GDSC;CCLE	7.780	Up-regulation
AGC_Akt_AKT1_ST	P22736	NR4A1	P31749	AKT1	T174	G169V	169	Missense	distal	-5	no	9.744	9.494	EPSD	GDSC;CCLE	7.780	Down-regulation
AGC_Akt_AKT1_ST	P42858	HTT	P31749	AKT1	S417	R416C	416	Missense	proximal	-1	no	11.391	11.321	EPSD	GDSC;CCLE	7.780	Down-regulation
AGC_Akt_AKT1_ST	P42858	HTT	P31749	AKT1	S417	R414*	414	Missense	distal	-3	no	11.391	-5.998	EPSD	GDSC	7.780	Loss
AGC_Akt_AKT1_ST	P42858	HTT	P31749	AKT1	S419	R416C	416	Missense	distal	-3	no	17.050	10.877	PhosphoSitePlus	GDSC;CCLE	7.780	Down-regulation
AGC_Akt_AKT1_ST	P42858	HTT	P31749	AKT1	S419	R414*	414	Missense	distal	-5	no	17.050	6.290	PhosphoSitePlus	GDSC	7.780	Loss
AGC_Akt_AKT1_ST	P42858	HTT	P31749	AKT1	S463	S457L	457	Missense	distal	-6	no	9.890	9.840	EPSD	GDSC	7.780	Down-regulation
AGC_Akt_AKT1_ST	P42858	HTT	P31749	AKT1	S2114	G2119V	2119	Missense	distal	5	no	12.204	12.208	EPSD	GDSC;CCLE	7.780	Up-regulation
AGC_Akt_AKT1_ST	P42858	HTT	P31749	AKT1	T2335	E2341K	2341	Missense	distal	6	no	12.576	12.646	EPSD	GDSC;CCLE	7.780	Up-regulation
AGC_Akt_AKT1_ST	P42858	HTT	P31749	AKT1	T2335	K2337R	2337	Missense	proximal	2	no	12.576	12.388	EPSD	GDSC	7.780	Down-regulation
AGC_Akt_AKT1_ST	P42858	HTT	P31749	AKT1	S2340	K2337R	2337	Missense	distal	-3	no	7.516	12.037	EPSD	GDSC	7.780	Gain
AGC_Akt_AKT1_ST	P05787	KRT8	P31749	AKT1	S9	T6S	6	Missense	distal	-3	no	8.946	8.191	EPSD	GDSC;CCLE	7.780	Down-regulation
AGC_Akt_AKT1_ST	P05787	KRT8	P31749	AKT1	S13	T6S	6	Missense	distal	-7	no	9.637	9.587	EPSD	GDSC;CCLE	7.780	Down-regulation
AGC_Akt_AKT1_ST	P05787	KRT8	P31749	AKT1	S280	E279G	279	Missense	proximal	-1	no	9.529	9.514	EPSD	GDSC;CCLE	7.780	Down-regulation
AGC_Akt_AKT1_ST	P05787	KRT8	P31749	AKT1	S280	K285Q	285	Missense	distal	5	no	9.529	9.484	EPSD	GDSC;CCLE	7.780	Down-regulation
AGC_Akt_AKT1_ST	P05787	KRT8	P31749	AKT1	S280	R273H	273	Missense	distal	-7	no	9.529	9.227	EPSD	GDSC	7.780	Down-regulation
AGC_Akt_AKT1_ST	P05787	KRT8	P31749	AKT1	S315	A319S	319	Missense	distal	4	no	10.926	10.802	EPSD	GDSC	7.780	Down-regulation
AGC_Akt_AKT1_ST	P05787	KRT8	P31749	AKT1	S315	A319G	319	Missense	distal	4	no	10.926	10.976	EPSD	GDSC;CCLE	7.780	Up-regulation
AGC_Akt_AKT1_ST	P05787	KRT8	P31749	AKT1	S404	E399V	399	Missense	distal	-5	no	11.574	11.354	EPSD	GDSC	7.780	Down-regulation
AGC_Akt_AKT1_ST	P05787	KRT8	P31749	AKT1	S417	T416A	416	Missense	proximal	-1	no	9.387	9.360	EPSD	GDSC;CCLE	7.780	Down-regulation
AGC_Akt_AKT1_ST	P05787	KRT8	P31749	AKT1	S417	G421A	421	Missense	distal	4	no	9.387	9.338	EPSD	GDSC	7.780	Down-regulation
AGC_Akt_AKT1_ST	P05787	KRT8	P31749	AKT1	S457	T455A	455	Missense	proximal	-2	no	13.915	13.529	EPSD	GDSC	7.780	Down-regulation
AGC_Akt_AKT1_ST	P05787	KRT8	P31749	AKT1	S458	T455A	455	Missense	distal	-3	no	7.870	8.588	EPSD	GDSC	7.780	Up-regulation
AGC_Akt_AKT1_ST	P05787	KRT8	P31749	AKT1	S475	T468I	468	Missense	distal	-7	no	9.810	9.388	EPSD	GDSC;CCLE	7.780	Down-regulation
AGC_Akt_AKT1_ST	P05787	KRT8	P31749	AKT1	S475	D479N	479	Missense	distal	4	no	9.810	9.695	EPSD	GDSC;CCLE	7.780	Down-regulation
AGC_Akt_AKT1_ST	P05787	KRT8	P31749	AKT1	S477	D479N	479	Missense	proximal	2	no	7.658	7.988	EPSD	GDSC;CCLE	7.780	Gain
AGC_Akt_AKT1_ST	P40818	USP8	P31749	AKT1	S425	T428R	428	Missense	distal	3	no	10.780	10.764	EPSD	GDSC;CCLE	7.780	Down-regulation
AGC_Akt_AKT1_ST	P40818	USP8	P31749	AKT1	S427	T428R	428	Missense	proximal	1	no	11.043	10.994	EPSD	GDSC;CCLE	7.780	Down-regulation
AGC_Akt_AKT1_ST	P40818	USP8	P31749	AKT1	T618	T618P	618	Missense	central	0	yes	10.098	0.000	EPSD	GDSC;CCLE	7.780	Loss
AGC_Akt_AKT1_ST	P40818	USP8	P31749	AKT1	T623	T618P	618	Missense	distal	-5	no	10.471	10.191	EPSD	GDSC;CCLE	7.780	Down-regulation
AGC_Akt_AKT1_ST	P40818	USP8	P31749	AKT1	S711	A704T	704	Missense	distal	-7	no	14.396	14.595	EPSD	GDSC;CCLE	7.780	Up-regulation
AGC_Akt_AKT1_ST	P40818	USP8	P31749	AKT1	T735	E730D	730	Missense	distal	-5	no	11.383	11.432	EPSD	GDSC;CCLE	7.780	Up-regulation
AGC_Akt_AKT1_ST	P40818	USP8	P31749	AKT1	T735	R742G	742	Missense	distal	7	no	11.383	11.302	EPSD	GDSC	7.780	Down-regulation
AGC_Akt_AKT1_ST	P40818	USP8	P31749	AKT1	T737	E730D	730	Missense	distal	-7	no	9.216	8.994	EPSD	GDSC;CCLE	7.780	Down-regulation
AGC_Akt_AKT1_ST	P40818	USP8	P31749	AKT1	T737	R742G	742	Missense	distal	5	no	9.216	9.145	EPSD	GDSC	7.780	Down-regulation
AGC_Akt_AKT1_ST	P40818	USP8	P31749	AKT1	S846	T839I	839	Missense	distal	-7	no	11.203	10.781	EPSD	GDSC	7.780	Down-regulation
AGC_Akt_AKT1_ST	P40818	USP8	P31749	AKT1	S972	S972A	972	Missense	central	0	yes	11.301	0.000	EPSD	GDSC	7.780	Loss
AGC_Akt_AKT1_ST	Q969H0	FBXW7	P31749	AKT1	S18	R13*	13	Missense	distal	-5	no	11.004	0.243	EPSD	GDSC	7.780	Loss
AGC_Akt_AKT1_ST	Q969H0	FBXW7	P31749	AKT1	S18	K11Q	11	Missense	distal	-7	no	11.004	10.822	EPSD	GDSC;CCLE	7.780	Down-regulation
AGC_Akt_AKT1_ST	Q969H0	FBXW7	P31749	AKT1	T692	E694*	694	Missense	proximal	2	no	12.179	11.383	EPSD	GDSC	7.780	Down-regulation
AGC_Akt_AKT1_ST	Q04912	MST1R	P31749	AKT1	S1056	L1062M	1062	Missense	distal	6	no	10.291	10.296	EPSD	GDSC;CCLE	7.780	Up-regulation
AGC_Akt_AKT1_ST	Q7Z589	EMSY	P31749	AKT1	S173	A175T	175	Missense	proximal	2	no	9.940	10.241	EPSD	GDSC	7.780	Up-regulation
AGC_Akt_AKT1_ST	Q7Z589	EMSY	P31749	AKT1	S173	N177S	177	Missense	distal	4	no	9.940	9.831	EPSD	GDSC	7.780	Down-regulation
AGC_Akt_AKT1_ST	Q7Z589	EMSY	P31749	AKT1	T207	S213F	213	Missense	distal	6	no	14.849	14.729	EPSD	GDSC	7.780	Down-regulation
AGC_Akt_AKT1_ST	Q7Z589	EMSY	P31749	AKT1	S209	S213F	213	Missense	distal	4	no	17.159	17.356	PhosphoSitePlus	GDSC	7.780	Up-regulation
AGC_Akt_AKT1_ST	Q7Z589	EMSY	P31749	AKT1	S210	S213F	213	Missense	distal	3	no	10.213	10.115	EPSD	GDSC	7.780	Down-regulation
AGC_Akt_AKT1_ST	Q7Z589	EMSY	P31749	AKT1	S211	S213F	213	Missense	proximal	2	no	9.785	9.207	EPSD	GDSC	7.780	Down-regulation
AGC_Akt_AKT1_ST	Q7Z589	EMSY	P31749	AKT1	S793	P798L	798	Missense	distal	5	no	9.791	9.778	EPSD	GDSC	7.780	Down-regulation
AGC_Akt_AKT1_ST	Q7Z589	EMSY	P31749	AKT1	S1210	C1207R	1207	Missense	distal	-3	no	6.955	13.129	EPSD	GDSC	7.780	Gain
AGC_Akt_AKT1_ST	Q7Z589	EMSY	P31749	AKT1	S1212	C1207R	1207	Missense	distal	-5	no	7.093	11.169	EPSD	GDSC	7.780	Gain
AGC_Akt_AKT1_ST	P45880	VDAC2	P31749	AKT1	S48	E51K	51	Missense	distal	3	no	9.494	9.538	PhosphoSitePlus	GDSC	7.780	Up-regulation
AGC_Akt_AKT1_ST	P45880	VDAC2	P31749	AKT1	S48	V50L	50	Missense	proximal	2	no	9.494	9.487	PhosphoSitePlus	GDSC;CCLE	7.780	Down-regulation
AGC_Akt_AKT1_ST	P63000	RAC1	P31749	AKT1	S71	Y64H	64	Missense	distal	-7	no	13.601	13.562	PhosphoSitePlus	GDSC;CCLE	7.780	Down-regulation
AGC_Akt_AKT1_ST	Q15121	PEA15	P31749	AKT1	S90	D93E	93	Missense	distal	3	no	9.680	9.751	EPSD	GDSC;CCLE	7.780	Up-regulation
AGC_Akt_AKT1_ST	O96028	NSD2	P31749	AKT1	S437	G434A	434	Missense	distal	-3	no	8.520	8.973	EPSD	GDSC	7.780	Up-regulation
AGC_Akt_AKT1_ST	O96028	NSD2	P31749	AKT1	S437	T444A	444	Missense	distal	7	no	8.520	8.459	EPSD	GDSC	7.780	Down-regulation
AGC_Akt_AKT1_ST	O96028	NSD2	P31749	AKT1	T444	T444A	444	Missense	central	0	yes	12.047	0.000	EPSD	GDSC	7.780	Loss
AGC_Akt_AKT1_ST	O96028	NSD2	P31749	AKT1	T445	T444A	444	Missense	proximal	-1	no	8.245	8.219	EPSD	GDSC	7.780	Down-regulation
AGC_Akt_AKT1_ST	O96028	NSD2	P31749	AKT1	S447	T444A	444	Missense	distal	-3	no	7.476	8.195	EPSD	GDSC	7.780	Gain
AGC_Akt_AKT1_ST	O96028	NSD2	P31749	AKT1	T551	T551M	551	Missense	central	0	yes	14.693	0.000	EPSD	GDSC	7.780	Loss
AGC_Akt_AKT1_ST	O96028	NSD2	P31749	AKT1	S555	T551M	551	Missense	distal	-4	no	11.167	10.201	EPSD	GDSC	7.780	Down-regulation
AGC_Akt_AKT1_ST	O96028	NSD2	P31749	AKT1	T605	R600*	600	Missense	distal	-5	no	14.319	3.559	EPSD	GDSC	7.780	Loss
AGC_Akt_AKT1_ST	P56270	MAZ	P31749	AKT1	S300	H297L	297	Missense	distal	-3	no	7.856	5.561	EPSD	GDSC;CCLE	7.780	Loss
AGC_Akt_AKT1_ST	P56270	MAZ	P31749	AKT1	S300	H297R	297	Missense	distal	-3	no	7.856	12.554	EPSD	GDSC;CCLE	7.780	Up-regulation
AGC_Akt_AKT1_ST	P56270	MAZ	P31749	AKT1	S302	H297R	297	Missense	distal	-5	no	6.398	9.493	EPSD	GDSC;CCLE	7.780	Gain
AGC_Akt_AKT1_ST	P56270	MAZ	P31749	AKT1	S323	R327C	327	Missense	distal	4	no	9.412	9.746	EPSD	GDSC;CCLE	7.780	Up-regulation
AGC_Akt_AKT1_ST	P09601	HMOX1	P31749	AKT1	S188	A194V	194	Missense	distal	6	no	16.283	16.251	PhosphoSitePlus	GDSC;CCLE	7.780	Down-regulation
AGC_Akt_AKT1_ST	Q13009	TIAM1	P31749	AKT1	S43	H41L	41	Missense	proximal	-2	no	15.019	15.212	EPSD	GDSC;CCLE	7.780	Up-regulation
AGC_Akt_AKT1_ST	Q13009	TIAM1	P31749	AKT1	S60	P62L	62	Missense	proximal	2	no	13.091	12.882	EPSD	GDSC;CCLE	7.780	Down-regulation
AGC_Akt_AKT1_ST	Q13009	TIAM1	P31749	AKT1	S224	P220S	220	Missense	distal	-4	no	9.607	10.344	EPSD	GDSC;CCLE	7.780	Up-regulation
AGC_Akt_AKT1_ST	Q13009	TIAM1	P31749	AKT1	S224	S224R	224	Missense	central	0	yes	9.607	0.000	EPSD	GDSC;CCLE	7.780	Loss
AGC_Akt_AKT1_ST	Q13009	TIAM1	P31749	AKT1	S231	S224R	224	Missense	distal	-7	no	11.969	12.025	PhosphoSitePlus	GDSC;CCLE	7.780	Up-regulation
AGC_Akt_AKT1_ST	Q13009	TIAM1	P31749	AKT1	T679	T679I	679	Missense	central	0	yes	9.345	0.000	EPSD	GDSC;CCLE	7.780	Loss
AGC_Akt_AKT1_ST	Q13009	TIAM1	P31749	AKT1	S1036	S1036L	1036	Missense	central	0	yes	8.483	0.000	EPSD	GDSC;CCLE	7.780	Loss
AGC_Akt_AKT1_ST	Q13009	TIAM1	P31749	AKT1	T1405	P1409H	1409	Missense	distal	4	no	7.860	7.899	EPSD	GDSC;CCLE	7.780	Up-regulation
AGC_Akt_AKT1_ST	Q13009	TIAM1	P31749	AKT1	T1405	Q1401R	1401	Missense	distal	-4	no	7.860	8.481	EPSD	GDSC;CCLE	7.780	Up-regulation
AGC_Akt_AKT1_ST	Q13009	TIAM1	P31749	AKT1	T1405	L1402I	1402	Missense	distal	-3	no	7.860	7.773	EPSD	GDSC;CCLE	7.780	Loss
AGC_Akt_AKT1_ST	O15151	MDM4	P31749	AKT1	S367	R363Q	363	Missense	distal	-4	no	11.696	11.075	PhosphoSitePlus	GDSC;CCLE	7.780	Down-regulation
AGC_Akt_AKT1_ST	Q7Z5H3	ARHGAP22	P31749	AKT1	S636	R634*	634	Missense	proximal	-2	no	8.147	6.292	EPSD	GDSC	7.780	Loss
AGC_Akt_AKT1_ST	Q7Z5H3	ARHGAP22	P31749	AKT1	S636	D630Y	630	Missense	distal	-6	no	8.147	8.207	EPSD	GDSC;CCLE	7.780	Up-regulation
TK_Src_SrcB_LYN_Y	Q9GZY6	LAT2	P07948	LYN	Y110	M116V	116	Missense	distal	6	no	3.541	3.493	EPSD;PhosphoSitePlus	GDSC	1.526	Down-regulation
TK_Src_SrcB_LYN_Y	Q9GZY6	LAT2	P07948	LYN	Y110	I111V	111	Missense	proximal	1	no	3.541	4.335	EPSD;PhosphoSitePlus	GDSC	1.526	Up-regulation
TK_Src_SrcB_LYN_Y	P30419	NMT1	P07948	LYN	Y41	N42S	42	Missense	proximal	1	no	1.437	2.083	EPSD	GDSC;CCLE	1.526	Gain
TK_Src_SrcB_LYN_Y	P30419	NMT1	P07948	LYN	Y117	P124S	124	Missense	distal	7	no	2.734	2.728	EPSD	GDSC;CCLE	1.526	Down-regulation
TK_Src_SrcB_LYN_Y	P30419	NMT1	P07948	LYN	Y117	P124L	124	Missense	distal	7	no	2.734	2.812	EPSD	GDSC;CCLE	1.526	Up-regulation
TK_Src_SrcB_LYN_Y	P30419	NMT1	P07948	LYN	Y327	E331*	331	Missense	distal	4	no	2.046	1.561	EPSD	GDSC	1.526	Down-regulation
TK_Src_SrcB_LYN_Y	P30419	NMT1	P07948	LYN	Y327	R322C	322	Missense	distal	-5	no	2.046	1.461	EPSD	GDSC;CCLE	1.526	Loss
TK_Src_SrcB_LYN_Y	P02730	SLC4A1	P07948	LYN	Y21	E19D	19	Missense	proximal	-2	no	3.161	3.334	EPSD;PhosphoSitePlus	GDSC;CCLE	1.526	Up-regulation
TK_Src_SrcB_LYN_Y	P02730	SLC4A1	P07948	LYN	Y359	G366V	366	Missense	distal	7	no	5.387	5.341	EPSD;PhosphoSitePlus	GDSC;CCLE	1.526	Down-regulation
TK_Src_SrcB_LYN_Y	P25490	YY1	P07948	LYN	Y145	G141S	141	Missense	distal	-4	no	1.370	2.026	EPSD	GDSC	1.526	Gain
TK_Src_SrcB_LYN_Y	O43823	AKAP8	P07948	LYN	Y80	A78S	78	Missense	proximal	-2	no	1.900	2.784	EPSD;PhosphoSitePlus	GDSC	1.526	Up-regulation
TK_Src_SrcB_LYN_Y	O43823	AKAP8	P07948	LYN	Y80	G81S	81	Missense	proximal	1	no	1.900	2.249	EPSD;PhosphoSitePlus	GDSC	1.526	Up-regulation
TK_Src_SrcB_LYN_Y	O43823	AKAP8	P07948	LYN	Y80	H76Y	76	Missense	distal	-4	no	1.900	2.786	EPSD;PhosphoSitePlus	GDSC	1.526	Up-regulation
TK_Src_SrcB_LYN_Y	O43823	AKAP8	P07948	LYN	Y80	P82A	82	Missense	proximal	2	no	1.900	2.167	EPSD;PhosphoSitePlus	GDSC;CCLE	1.526	Up-regulation
TK_Src_SrcB_LYN_Y	O43823	AKAP8	P07948	LYN	Y146	Y150C	150	Missense	distal	4	no	4.024	4.007	EPSD;PhosphoSitePlus	GDSC	1.526	Down-regulation
TK_Src_SrcB_LYN_Y	O43823	AKAP8	P07948	LYN	Y150	Y150C	150	Missense	central	0	yes	2.172	0.000	EPSD;PhosphoSitePlus	GDSC	1.526	Loss
TK_Src_SrcB_LYN_Y	O43823	AKAP8	P07948	LYN	Y154	Y150C	150	Missense	distal	-4	no	2.317	-0.818	EPSD;PhosphoSitePlus	GDSC	1.526	Loss
TK_Src_SrcB_LYN_Y	P11274	BCR	P07948	LYN	Y177	F176L	176	Missense	proximal	-1	no	5.347	4.951	PhosphoSitePlus	GDSC;CCLE	1.526	Down-regulation
TK_Src_SrcB_LYN_Y	P11274	BCR	P07948	LYN	Y279	Y279H	279	Missense	central	0	yes	2.613	0.000	EPSD	GDSC;CCLE	1.526	Loss
TK_Src_SrcB_LYN_Y	P11274	BCR	P07948	LYN	Y283	Y279H	279	Missense	distal	-4	no	2.669	1.784	EPSD	GDSC;CCLE	1.526	Down-regulation
TK_Src_SrcB_LYN_Y	P11274	BCR	P07948	LYN	Y360	R361C	361	Missense	proximal	1	no	2.787	2.878	EPSD	GDSC;CCLE	1.526	Up-regulation
TK_Src_SrcB_LYN_Y	O15492	RGS16	P07948	LYN	Y177	Q183R	183	Missense	distal	6	no	2.350	2.450	PhosphoSitePlus;EPSD	GDSC;CCLE	1.526	Up-regulation
TK_Src_SrcB_LYN_Y	O15492	RGS16	P07948	LYN	Y177	D179A	179	Missense	proximal	2	no	2.350	2.292	PhosphoSitePlus;EPSD	GDSC;CCLE	1.526	Down-regulation
TK_Src_SrcB_LYN_Y	Q06187	BTK	P07948	LYN	Y551	D549A	549	Missense	proximal	-2	no	6.089	5.683	EPSD;PhosphoSitePlus	GDSC;CCLE	1.526	Down-regulation
TK_Src_SrcB_LYN_Y	P12318	FCGR2A	P07948	LYN	Y281	L274F	274	Missense	distal	-7	no	4.134	4.249	EPSD	GDSC	1.526	Up-regulation
TK_Src_SrcB_LYN_Y	Q13263	TRIM28	P07948	LYN	Y517	E515K	515	Missense	proximal	-2	no	3.224	2.511	PhosphoSitePlus;EPSD	GDSC;CCLE	1.526	Down-regulation
TK_Src_SrcB_LYN_Y	Q13263	TRIM28	P07948	LYN	Y517	T514N	514	Missense	distal	-3	no	3.224	1.995	PhosphoSitePlus;EPSD	GDSC;CCLE	1.526	Down-regulation
TK_Src_SrcB_LYN_Y	Q14790	CASP8	P07948	LYN	Y380	S375P	375	Missense	distal	-5	no	5.343	5.577	PhosphoSitePlus;EPSD	GDSC	1.526	Up-regulation
TK_Src_SrcB_LYN_Y	P29350	PTPN6	P07948	LYN	Y377	M370I	370	Missense	distal	-7	no	2.801	2.708	EPSD	GDSC;CCLE	1.526	Down-regulation
TK_Src_SrcB_LYN_Y	P29350	PTPN6	P07948	LYN	Y536	S534L	534	Missense	proximal	-2	no	5.656	2.788	PhosphoSitePlus	GDSC	1.526	Down-regulation
TK_Src_SrcB_LYN_Y	P46527	CDKN1B	P07948	LYN	Y88	E86K	86	Missense	proximal	-2	no	4.687	3.974	PhosphoSitePlus	GDSC;CCLE	1.526	Down-regulation
TK_Src_SrcB_LYN_Y	P60484	PTEN	P07948	LYN	Y27	L25*	25	Missense	proximal	-2	no	1.661	-0.621	EPSD	GDSC	1.526	Loss
TK_Src_SrcB_LYN_Y	P60484	PTEN	P07948	LYN	Y46	V53E	53	Missense	distal	7	no	2.264	2.249	EPSD	GDSC	1.526	Down-regulation
TK_Src_SrcB_LYN_Y	P60484	PTEN	P07948	LYN	Y178	Y177*	177	Missense	proximal	-1	no	4.329	1.877	EPSD	GDSC	1.526	Down-regulation
TK_Src_SrcB_LYN_Y	P22681	CBL	P07948	LYN	Y774	D772E	772	Missense	proximal	-2	no	2.517	2.344	EPSD	GDSC	1.526	Down-regulation
TK_Src_SrcB_LYN_Y	P14317	HCLS1	P07948	LYN	Y378	N376T	376	Missense	proximal	-2	no	4.497	4.445	EPSD	GDSC	1.526	Down-regulation
TK_Src_SrcB_LYN_Y	P14317	HCLS1	P07948	LYN	Y378	N376H	376	Missense	proximal	-2	no	4.497	4.326	EPSD	GDSC	1.526	Down-regulation
TK_Src_SrcB_LYN_Y	P14317	HCLS1	P07948	LYN	Y397	V400A	400	Missense	distal	3	no	4.274	3.139	EPSD	GDSC;CCLE	1.526	Down-regulation
TK_Src_SrcB_LYN_Y	Q8N6F7	GCSAM	P07948	LYN	Y80	Y80D	80	Missense	central	0	yes	2.509	0.000	EPSD	GDSC	1.526	Loss
TK_Src_SrcB_LYN_Y	O14920	IKBKB	P07948	LYN	Y199	Y199C	199	Missense	central	0	yes	2.659	0.000	EPSD;PhosphoSitePlus	GDSC;CCLE	1.526	Loss
TK_Src_SrcB_LYN_Y	Q9H792	PEAK1	P07948	LYN	Y1620	A1623T	1623	Missense	distal	3	no	3.096	3.497	EPSD	GDSC;CCLE	1.526	Up-regulation
TK_Src_SrcB_LYN_Y	Q9H792	PEAK1	P07948	LYN	Y1620	R1622L	1622	Missense	proximal	2	no	3.096	3.091	EPSD	GDSC;CCLE	1.526	Down-regulation
TK_Src_SrcB_LYN_Y	P42768	WAS	P07948	LYN	Y212	I207M	207	Missense	distal	-5	no	3.424	3.296	EPSD	GDSC;CCLE	1.526	Down-regulation
TK_Src_SrcB_LYN_Y	P33993	MCM7	P07948	LYN	Y600	S595N	595	Missense	distal	-5	no	3.399	3.483	PhosphoSitePlus	GDSC	1.526	Up-regulation
TK_Src_SrcB_LYN_Y	P35354	PTGS2	P07948	LYN	Y116	N117T	117	Missense	proximal	1	no	1.193	2.109	EPSD	GDSC;CCLE	1.526	Gain
TK_Src_SrcB_LYN_Y	P35354	PTGS2	P07948	LYN	Y120	N117T	117	Missense	distal	-3	no	2.017	3.246	PhosphoSitePlus	GDSC;CCLE	1.526	Up-regulation
AGC_RSK_RSKp90_RPS6KA3_ST	Q99683	MAP3K5	P51812	RPS6KA3	S82	S83C	83	Missense	proximal	1	no	2.365	2.424	EPSD	GDSC;CCLE	1.803	Up-regulation
AGC_RSK_RSKp90_RPS6KA3_ST	Q99683	MAP3K5	P51812	RPS6KA3	S83	S83C	83	Missense	central	0	yes	4.412	0.000	PhosphoSitePlus;EPSD	GDSC;CCLE	1.803	Loss
AGC_RSK_RSKp90_RPS6KA3_ST	Q99683	MAP3K5	P51812	RPS6KA3	S269	S267R	267	Missense	proximal	-2	no	1.596	2.012	EPSD	GDSC	1.803	Gain
AGC_RSK_RSKp90_RPS6KA3_ST	Q99683	MAP3K5	P51812	RPS6KA3	S763	G760R	760	Missense	distal	-3	no	1.187	3.569	EPSD	GDSC	1.803	Gain
AGC_RSK_RSKp90_RPS6KA3_ST	Q99683	MAP3K5	P51812	RPS6KA3	T1059	D1063Y	1063	Missense	distal	4	no	2.286	2.293	EPSD	GDSC	1.803	Up-regulation
AGC_RSK_RSKp90_RPS6KA3_ST	Q92934	BAD	P51812	RPS6KA3	S134	T137K	137	Missense	distal	3	no	3.650	3.645	EPSD	GDSC	1.803	Down-regulation
AGC_RSK_RSKp90_RPS6KA3_ST	Q92934	BAD	P51812	RPS6KA3	S134	L129F	129	Missense	distal	-5	no	3.650	3.547	EPSD	GDSC	1.803	Down-regulation
AGC_RSK_RSKp90_RPS6KA3_ST	Q92934	BAD	P51812	RPS6KA3	S144	F151L	151	Missense	distal	7	no	1.897	1.885	EPSD	GDSC;CCLE	1.803	Down-regulation
AGC_RSK_RSKp90_RPS6KA3_ST	Q92934	BAD	P51812	RPS6KA3	S144	T137K	137	Missense	distal	-7	no	1.897	1.881	EPSD	GDSC	1.803	Down-regulation
AGC_RSK_RSKp90_RPS6KA3_ST	Q92934	BAD	P51812	RPS6KA3	S145	F151L	151	Missense	distal	6	no	3.509	3.524	EPSD	GDSC;CCLE	1.803	Up-regulation
AGC_RSK_RSKp90_RPS6KA3_ST	Q8IX03	WWC1	P51812	RPS6KA3	S208	Y209C	209	Missense	proximal	1	no	1.900	1.897	EPSD	GDSC;CCLE	1.803	Down-regulation
AGC_RSK_RSKp90_RPS6KA3_ST	Q8IX03	WWC1	P51812	RPS6KA3	S358	E353Q	353	Missense	distal	-5	no	3.731	3.738	EPSD	GDSC;CCLE	1.803	Up-regulation
AGC_RSK_RSKp90_RPS6KA3_ST	Q8IX03	WWC1	P51812	RPS6KA3	S525	Q519H	519	Missense	distal	-6	no	4.098	4.085	EPSD	GDSC;CCLE	1.803	Down-regulation
AGC_RSK_RSKp90_RPS6KA3_ST	Q8IX03	WWC1	P51812	RPS6KA3	T912	K906E	906	Missense	distal	-6	no	1.905	1.884	EPSD	GDSC;CCLE	1.803	Down-regulation
AGC_RSK_RSKp90_RPS6KA3_ST	Q8IX03	WWC1	P51812	RPS6KA3	T912	L919F	919	Missense	distal	7	no	1.905	1.916	EPSD	GDSC;CCLE	1.803	Up-regulation
AGC_RSK_RSKp90_RPS6KA3_ST	Q8IX03	WWC1	P51812	RPS6KA3	S922	L919F	919	Missense	distal	-3	no	1.866	1.236	EPSD	GDSC;CCLE	1.803	Loss
AGC_RSK_RSKp90_RPS6KA3_ST	Q8IX03	WWC1	P51812	RPS6KA3	S922	R920Q	920	Missense	proximal	-2	no	1.866	1.341	EPSD	GDSC;CCLE	1.803	Loss
AGC_RSK_RSKp90_RPS6KA3_ST	Q8IX03	WWC1	P51812	RPS6KA3	T923	L919F	919	Missense	distal	-4	no	1.879	1.829	EPSD	GDSC;CCLE	1.803	Down-regulation
AGC_RSK_RSKp90_RPS6KA3_ST	Q8IX03	WWC1	P51812	RPS6KA3	T923	R920Q	920	Missense	distal	-3	no	1.879	-0.628	EPSD	GDSC;CCLE	1.803	Loss
AGC_RSK_RSKp90_RPS6KA3_ST	Q8IX03	WWC1	P51812	RPS6KA3	S947	R941Q	941	Missense	distal	-6	no	3.802	3.735	PhosphoSitePlus;EPSD	GDSC	1.803	Down-regulation
AGC_RSK_RSKp90_RPS6KA3_ST	Q8IX03	WWC1	P51812	RPS6KA3	S974	R972W	972	Missense	proximal	-2	no	2.314	1.756	EPSD	GDSC;CCLE	1.803	Loss
AGC_RSK_RSKp90_RPS6KA3_ST	Q8IX03	WWC1	P51812	RPS6KA3	S975	R972W	972	Missense	distal	-3	no	3.999	1.457	EPSD	GDSC;CCLE	1.803	Loss
AGC_RSK_RSKp90_RPS6KA3_ST	Q8IX03	WWC1	P51812	RPS6KA3	S978	R972W	972	Missense	distal	-6	no	1.965	1.885	EPSD	GDSC;CCLE	1.803	Down-regulation
AGC_RSK_RSKp90_RPS6KA3_ST	Q8IX03	WWC1	P51812	RPS6KA3	S978	I985V	985	Missense	distal	7	no	1.965	1.975	EPSD	GDSC;CCLE	1.803	Up-regulation
AGC_RSK_RSKp90_RPS6KA3_ST	P16220	CREB1	P51812	RPS6KA3	S111	S111L	111	Missense	central	0	yes	1.833	0.000	EPSD	GDSC;CCLE	1.803	Loss
AGC_RSK_RSKp90_RPS6KA3_ST	P49841	GSK3B	P51812	RPS6KA3	T7	T8P	8	Missense	proximal	1	no	2.033	2.001	EPSD	GDSC	1.803	Down-regulation
AGC_RSK_RSKp90_RPS6KA3_ST	P49841	GSK3B	P51812	RPS6KA3	S9	T8P	8	Missense	proximal	-1	no	4.283	4.304	PhosphoSitePlus	GDSC	1.803	Up-regulation
AGC_RSK_RSKp90_RPS6KA3_ST	Q9H6Z4	RANBP3	P51812	RPS6KA3	S333	E329*	329	Missense	distal	-4	no	3.229	3.188	EPSD	GDSC	1.803	Down-regulation
AGC_RSK_RSKp90_RPS6KA3_ST	P19525	EIF2AK2	P51812	RPS6KA3	S181	E187K	187	Missense	distal	6	no	1.851	1.864	EPSD	GDSC;CCLE	1.803	Up-regulation
AGC_RSK_RSKp90_RPS6KA3_ST	P03372	ESR1	P51812	RPS6KA3	S154	R151H	151	Missense	distal	-3	no	3.503	0.965	EPSD	GDSC	1.803	Loss
AGC_RSK_RSKp90_RPS6KA3_ST	P03372	ESR1	P51812	RPS6KA3	S154	G160S	160	Missense	distal	6	no	3.503	3.548	EPSD	GDSC	1.803	Up-regulation
AGC_RSK_RSKp90_RPS6KA3_ST	P03372	ESR1	P51812	RPS6KA3	S167	G160S	160	Missense	distal	-7	no	4.193	4.176	PhosphoSitePlus	GDSC	1.803	Down-regulation
AGC_RSK_RSKp90_RPS6KA3_ST	P03372	ESR1	P51812	RPS6KA3	S167	R164I	164	Missense	distal	-3	no	4.193	1.727	PhosphoSitePlus	GDSC;CCLE	1.803	Loss
AGC_RSK_RSKp90_RPS6KA3_ST	P03372	ESR1	P51812	RPS6KA3	S236	R241L	241	Missense	distal	5	no	4.297	4.407	EPSD	GDSC;CCLE	1.803	Up-regulation
AGC_RSK_RSKp90_RPS6KA3_ST	P03372	ESR1	P51812	RPS6KA3	S305	K299N	299	Missense	distal	-6	no	1.964	1.949	EPSD	GDSC;CCLE	1.803	Down-regulation
AGC_RSK_RSKp90_RPS6KA3_ST	P03372	ESR1	P51812	RPS6KA3	S305	I298V	298	Missense	distal	-7	no	1.964	1.968	EPSD	GDSC	1.803	Up-regulation
AGC_RSK_RSKp90_RPS6KA3_ST	P62753	RPS6	P51812	RPS6KA3	S235	S242F	242	Missense	distal	7	no	4.089	4.147	EPSD;PhosphoSitePlus	GDSC	1.803	Up-regulation
AGC_RSK_RSKp90_RPS6KA3_ST	P62753	RPS6	P51812	RPS6KA3	S236	S242F	242	Missense	distal	6	no	4.462	4.394	PhosphoSitePlus;EPSD	GDSC	1.803	Down-regulation
AGC_RSK_RSKp90_RPS6KA3_ST	P62753	RPS6	P51812	RPS6KA3	S240	S242F	242	Missense	proximal	2	no	2.396	2.264	EPSD	GDSC	1.803	Down-regulation
AGC_RSK_RSKp90_RPS6KA3_ST	P62753	RPS6	P51812	RPS6KA3	T241	S242F	242	Missense	proximal	1	no	2.166	2.250	EPSD	GDSC	1.803	Up-regulation
AGC_RSK_RSKp90_RPS6KA3_ST	P62753	RPS6	P51812	RPS6KA3	S247	S242F	242	Missense	distal	-5	no	1.829	1.696	EPSD	GDSC	1.803	Loss
AGC_RSK_RSKp90_RPS6KA3_ST	P67809	YBX1	P51812	RPS6KA3	S102	N95I	95	Missense	distal	-7	no	1.917	1.921	PhosphoSitePlus	GDSC;CCLE	1.803	Up-regulation
AGC_RSK_RSKp90_RPS6KA3_ST	P67809	YBX1	P51812	RPS6KA3	T271	G268R	268	Missense	distal	-3	no	-0.495	1.887	EPSD	GDSC	1.803	Gain
AGC_RSK_RSKp90_RPS6KA3_ST	P13796	LCP1	P51812	RPS6KA3	T503	W496*	496	Missense	distal	-7	no	2.317	2.320	EPSD	GDSC	1.803	Up-regulation
AGC_RSK_RSKp90_RPS6KA3_ST	P19105	MYL12A	P51812	RPS6KA3	S19	R13L	13	Missense	distal	-6	no	3.466	3.384	PhosphoSitePlus	GDSC;CCLE	1.803	Down-regulation
AGC_RSK_RSKp90_RPS6KA3_ST	Q9UL17	TBX21	P51812	RPS6KA3	S394	E398Q	398	Missense	distal	4	no	3.886	3.880	EPSD	GDSC;CCLE	1.803	Down-regulation
AGC_RSK_RSKp90_RPS6KA3_ST	Q9UL17	TBX21	P51812	RPS6KA3	S403	E398Q	398	Missense	distal	-5	no	3.868	3.876	EPSD	GDSC;CCLE	1.803	Up-regulation
AGC_RSK_RSKp90_RPS6KA3_ST	P53355	DAPK1	P51812	RPS6KA3	S57	R58L	58	Missense	proximal	1	no	3.715	3.815	EPSD	GDSC	1.803	Up-regulation
AGC_RSK_RSKp90_RPS6KA3_ST	P53355	DAPK1	P51812	RPS6KA3	S313	Q307K	307	Missense	distal	-6	no	3.844	3.858	EPSD	GDSC	1.803	Up-regulation
AGC_RSK_RSKp90_RPS6KA3_ST	P53355	DAPK1	P51812	RPS6KA3	S725	P732A	732	Missense	distal	7	no	3.723	3.714	EPSD	GDSC;CCLE	1.803	Down-regulation
AGC_RSK_RSKp90_RPS6KA3_ST	P53355	DAPK1	P51812	RPS6KA3	S728	P732A	732	Missense	distal	4	no	1.910	1.897	EPSD	GDSC;CCLE	1.803	Down-regulation
AGC_RSK_RSKp90_RPS6KA3_ST	Q16821	PPP1R3A	P51812	RPS6KA3	S65	D68E	68	Missense	distal	3	no	4.168	4.166	EPSD;PhosphoSitePlus	GDSC;CCLE	1.803	Down-regulation
AGC_RSK_RSKp90_RPS6KA3_ST	Q16821	PPP1R3A	P51812	RPS6KA3	S65	F72L	72	Missense	distal	7	no	4.168	4.156	EPSD;PhosphoSitePlus	GDSC;CCLE	1.803	Down-regulation
AGC_RSK_RSKp90_RPS6KA3_ST	Q16821	PPP1R3A	P51812	RPS6KA3	S375	S379*	379	Missense	distal	4	no	3.509	3.575	EPSD	GDSC	1.803	Up-regulation
AGC_RSK_RSKp90_RPS6KA3_ST	Q16821	PPP1R3A	P51812	RPS6KA3	S377	S379*	379	Missense	proximal	2	no	2.147	2.030	EPSD	GDSC	1.803	Down-regulation
AGC_RSK_RSKp90_RPS6KA3_ST	Q16821	PPP1R3A	P51812	RPS6KA3	S377	V384A	384	Missense	distal	7	no	2.147	2.115	EPSD	GDSC;CCLE	1.803	Down-regulation
AGC_RSK_RSKp90_RPS6KA3_ST	P18848	ATF4	P51812	RPS6KA3	S74	A78V	78	Missense	distal	4	no	1.839	1.880	EPSD	GDSC	1.803	Up-regulation
AGC_RSK_RSKp90_RPS6KA3_ST	P32314	FOXN2	P51812	RPS6KA3	T15	I21V	21	Missense	distal	6	no	1.918	1.907	EPSD	GDSC;CCLE	1.803	Down-regulation
AGC_RSK_RSKp90_RPS6KA3_ST	P32314	FOXN2	P51812	RPS6KA3	S211	S215Y	215	Missense	distal	4	no	1.796	1.863	EPSD	GDSC;CCLE	1.803	Gain
AGC_RSK_RSKp90_RPS6KA3_ST	P11362	FGFR1	P51812	RPS6KA3	T428	R424H	424	Missense	distal	-4	no	2.143	1.955	EPSD	GDSC	1.803	Down-regulation
AGC_RSK_RSKp90_RPS6KA3_ST	P11362	FGFR1	P51812	RPS6KA3	S786	E792K	792	Missense	distal	6	no	1.919	1.933	EPSD	GDSC;CCLE	1.803	Up-regulation
AGC_RSK_RSKp90_RPS6KA3_ST	P11362	FGFR1	P51812	RPS6KA3	S789	E792K	792	Missense	distal	3	no	1.807	1.805	PhosphoSitePlus	GDSC;CCLE	1.803	Down-regulation
AGC_RSK_RSKp90_RPS6KA3_ST	P11362	FGFR1	P51812	RPS6KA3	S794	E792K	792	Missense	proximal	-2	no	1.785	1.896	EPSD	GDSC;CCLE	1.803	Gain
AGC_RSK_RSKp90_RPS6KA3_ST	P16949	STMN1	P51812	RPS6KA3	S16	E10K	10	Missense	distal	-6	no	2.071	2.091	PhosphoSitePlus	GDSC;CCLE	1.803	Up-regulation
AGC_RSK_RSKp90_RPS6KA3_ST	P16949	STMN1	P51812	RPS6KA3	S16	E10*	10	Missense	distal	-6	no	2.071	2.053	PhosphoSitePlus	GDSC	1.803	Down-regulation
AGC_RSK_RSKp90_RPS6KA3_ST	P16949	STMN1	P51812	RPS6KA3	S139	E138*	138	Missense	proximal	-1	no	1.844	1.826	EPSD	GDSC	1.803	Down-regulation
AGC_RSK_RSKp90_RPS6KA3_ST	P29317	EPHA2	P51812	RPS6KA3	S636	S636L	636	Missense	central	0	yes	1.915	0.000	EPSD	GDSC;CCLE	1.803	Loss
AGC_RSK_RSKp90_RPS6KA3_ST	P29317	EPHA2	P51812	RPS6KA3	S897	P896R	896	Missense	proximal	-1	no	3.710	3.765	PhosphoSitePlus	GDSC;CCLE	1.803	Up-regulation
AGC_RSK_RSKp90_RPS6KA3_ST	P29317	EPHA2	P51812	RPS6KA3	S899	P896R	896	Missense	distal	-3	no	2.455	4.569	EPSD	GDSC;CCLE	1.803	Up-regulation
AGC_RSK_RSKp90_RPS6KA3_ST	P29317	EPHA2	P51812	RPS6KA3	S901	P896R	896	Missense	distal	-5	no	1.609	1.933	EPSD	GDSC;CCLE	1.803	Gain
AGC_RSK_RSKp90_RPS6KA3_ST	P48764	SLC9A3	P51812	RPS6KA3	S577	T573K	573	Missense	distal	-4	no	1.770	1.859	EPSD	GDSC;CCLE	1.803	Gain
AGC_RSK_RSKp90_RPS6KA3_ST	P48764	SLC9A3	P51812	RPS6KA3	T578	T573K	573	Missense	distal	-5	no	1.742	1.819	EPSD	GDSC;CCLE	1.803	Gain
AGC_RSK_RSKp90_RPS6KA3_ST	P48764	SLC9A3	P51812	RPS6KA3	S663	R660C	660	Missense	distal	-3	no	4.081	1.471	PhosphoSitePlus	GDSC;CCLE	1.803	Loss
AGC_RSK_RSKp90_RPS6KA3_ST	P48764	SLC9A3	P51812	RPS6KA3	S808	F804I	804	Missense	distal	-4	no	4.040	4.092	EPSD	GDSC;CCLE	1.803	Up-regulation
AGC_RSK_RSKp90_RPS6KA3_ST	P48764	SLC9A3	P51812	RPS6KA3	S810	F804I	804	Missense	distal	-6	no	2.158	2.183	EPSD	GDSC;CCLE	1.803	Up-regulation
AGC_RSK_RSKp90_RPS6KA3_ST	Q96RK0	CIC	P51812	RPS6KA3	S277	R274P	274	Missense	distal	-3	no	4.091	1.977	EPSD	GDSC	1.803	Down-regulation
AGC_RSK_RSKp90_RPS6KA3_ST	Q96RK0	CIC	P51812	RPS6KA3	S279	R274P	274	Missense	distal	-5	no	2.543	2.219	EPSD	GDSC	1.803	Down-regulation
AGC_RSK_RSKp90_RPS6KA3_ST	Q96RK0	CIC	P51812	RPS6KA3	S424	S431T	431	Missense	distal	7	no	1.837	1.885	EPSD	GDSC;CCLE	1.803	Up-regulation
AGC_RSK_RSKp90_RPS6KA3_ST	Q96RK0	CIC	P51812	RPS6KA3	S426	S431T	431	Missense	distal	5	no	1.932	2.006	EPSD	GDSC;CCLE	1.803	Up-regulation
AGC_RSK_RSKp90_RPS6KA3_ST	Q96RK0	CIC	P51812	RPS6KA3	S1309	S1306R	1306	Missense	distal	-3	no	1.460	3.467	EPSD	GDSC;CCLE	1.803	Gain
AGC_RSK_RSKp90_RPS6KA3_ST	Q96RK0	CIC	P51812	RPS6KA3	S1310	S1306R	1306	Missense	distal	-4	no	1.756	1.852	EPSD	GDSC;CCLE	1.803	Gain
AGC_RSK_RSKp90_RPS6KA3_ST	Q96RK0	CIC	P51812	RPS6KA3	S1311	S1306R	1306	Missense	distal	-5	no	1.587	1.904	EPSD	GDSC;CCLE	1.803	Gain
AGC_RSK_RSKp90_RPS6KA3_ST	Q96RK0	CIC	P51812	RPS6KA3	S1351	N1347S	1347	Missense	distal	-4	no	3.301	3.364	EPSD	GDSC	1.803	Up-regulation
AGC_RSK_RSKp90_RPS6KA3_ST	P05198	EIF2S1	P51812	RPS6KA3	S58	R54W	54	Missense	distal	-4	no	4.028	3.838	EPSD	GDSC;CCLE	1.803	Down-regulation
CK1_TTBK_TTBK2_ST	Q7L0J3	SV2A	Q6IQ55	TTBK2	S42	F49S	49	Missense	distal	7	no	7.526	7.515	EPSD;PhosphoSitePlus	GDSC;CCLE	3.341	Down-regulation
CK1_TTBK_TTBK2_ST	Q7L0J3	SV2A	Q6IQ55	TTBK2	S45	F49S	49	Missense	distal	4	no	7.586	7.398	EPSD;PhosphoSitePlus	GDSC;CCLE	3.341	Down-regulation
CK1_TTBK_TTBK2_ST	Q7L0J3	SV2A	Q6IQ55	TTBK2	S47	F49S	49	Missense	proximal	2	no	7.658	7.528	PhosphoSitePlus;EPSD	GDSC;CCLE	3.341	Down-regulation
CK1_TTBK_TTBK2_ST	Q7L0J3	SV2A	Q6IQ55	TTBK2	S80	S81G	81	Missense	proximal	1	no	6.833	6.876	EPSD;PhosphoSitePlus	GDSC;CCLE	3.341	Up-regulation
CK1_TTBK_TTBK2_ST	Q7L0J3	SV2A	Q6IQ55	TTBK2	S81	S81G	81	Missense	central	0	yes	7.524	0.000	EPSD;PhosphoSitePlus	GDSC;CCLE	3.341	Loss
CK1_TTBK_TTBK2_ST	Q7L0J3	SV2A	Q6IQ55	TTBK2	T84	S81G	81	Missense	distal	-3	no	6.838	6.858	EPSD;PhosphoSitePlus	GDSC;CCLE	3.341	Up-regulation
CK1_TTBK_TTBK2_ST	Q7L0J3	SV2A	Q6IQ55	TTBK2	S482	Q476H	476	Missense	distal	-6	no	3.525	3.575	EPSD	GDSC;CCLE	3.341	Up-regulation
TK_Tec_BTK_Y	Q06187	BTK	Q06187	BTK	Y241	L244*	244	Missense	distal	3	no	1.825	1.740	EPSD	GDSC	1.787	Loss
TK_Tec_BTK_Y	Q06187	BTK	Q06187	BTK	Y241	E240D	240	Missense	proximal	-1	no	1.825	1.854	EPSD	GDSC	1.787	Up-regulation
TK_Tec_BTK_Y	Q06187	BTK	Q06187	BTK	Y375	Q379*	379	Missense	distal	4	no	2.212	2.294	EPSD	GDSC	1.787	Up-regulation
TK_Tec_BTK_Y	Q06187	BTK	Q06187	BTK	Y551	D549A	549	Missense	proximal	-2	no	2.892	2.850	EPSD;PhosphoSitePlus	GDSC;CCLE	1.787	Down-regulation
TK_Tec_BTK_Y	Q08881	ITK	Q06187	BTK	Y180	V176A	176	Missense	distal	-4	no	4.386	4.337	PhosphoSitePlus	GDSC;CCLE	1.787	Down-regulation
TK_Tec_BTK_Y	Q08881	ITK	Q06187	BTK	Y512	T518I	518	Missense	distal	6	no	1.623	1.793	EPSD	GDSC;CCLE	1.787	Gain
TK_Tec_BTK_Y	Q08881	ITK	Q06187	BTK	Y512	Q511*	511	Missense	proximal	-1	no	1.623	1.813	EPSD	GDSC	1.787	Gain
TKL_IRAK_IRAK4_ST	Q96FA3	PELI1	Q9NWZ3	IRAK4	T80	T86N	86	Missense	distal	6	no	189.204	183.614	PhosphoSitePlus;EPSD	GDSC;CCLE	132.233	Down-regulation
TKL_IRAK_IRAK4_ST	Q96FA3	PELI1	Q9NWZ3	IRAK4	S82	T86N	86	Missense	distal	4	no	173.524	169.143	EPSD;PhosphoSitePlus	GDSC;CCLE	132.233	Down-regulation
TKL_IRAK_IRAK4_ST	Q96FA3	PELI1	Q9NWZ3	IRAK4	T86	T86N	86	Missense	central	0	yes	195.317	0.000	EPSD;PhosphoSitePlus	GDSC;CCLE	132.233	Loss
TKL_IRAK_IRAK4_ST	Q96FA3	PELI1	Q9NWZ3	IRAK4	T127	D126A	126	Missense	proximal	-1	no	207.540	207.275	EPSD;PhosphoSitePlus	GDSC;CCLE	132.233	Down-regulation
TKL_IRAK_IRAK4_ST	Q96FA3	PELI1	Q9NWZ3	IRAK4	T288	P292S	292	Missense	distal	4	no	161.359	161.358	EPSD;PhosphoSitePlus	GDSC;CCLE	132.233	Down-regulation
TKL_IRAK_IRAK4_ST	Q96FA3	PELI1	Q9NWZ3	IRAK4	S293	P292S	292	Missense	proximal	-1	no	169.983	170.002	EPSD;PhosphoSitePlus	GDSC;CCLE	132.233	Up-regulation
TKL_IRAK_IRAK4_ST	Q9NWZ3	IRAK4	Q9NWZ3	IRAK4	T6	I5V	5	Missense	proximal	-1	no	240.049	239.024	EPSD;PhosphoSitePlus	GDSC	132.233	Down-regulation
TKL_IRAK_IRAK4_ST	Q9NWZ3	IRAK4	Q9NWZ3	IRAK4	S8	I5V	5	Missense	distal	-3	no	283.097	282.304	EPSD;PhosphoSitePlus	GDSC	132.233	Down-regulation
TKL_IRAK_IRAK4_ST	Q9NWZ3	IRAK4	Q9NWZ3	IRAK4	S150	P153A	153	Missense	distal	3	no	169.510	171.506	EPSD;PhosphoSitePlus	GDSC;CCLE	132.233	Up-regulation
TKL_IRAK_IRAK4_ST	Q9NWZ3	IRAK4	Q9NWZ3	IRAK4	S151	P153A	153	Missense	proximal	2	no	174.237	171.913	EPSD;PhosphoSitePlus	GDSC;CCLE	132.233	Down-regulation
TKL_IRAK_IRAK4_ST	Q9NWZ3	IRAK4	Q9NWZ3	IRAK4	S152	P153A	153	Missense	proximal	1	no	174.796	170.104	EPSD;PhosphoSitePlus	GDSC;CCLE	132.233	Down-regulation
TKL_IRAK_IRAK4_ST	Q9NWZ3	IRAK4	Q9NWZ3	IRAK4	S157	P153A	153	Missense	distal	-4	no	134.629	118.520	EPSD	GDSC;CCLE	132.233	Loss
TKL_IRAK_IRAK4_ST	Q9NWZ3	IRAK4	Q9NWZ3	IRAK4	S423	K416R	416	Missense	distal	-7	no	140.113	131.053	EPSD	GDSC;CCLE	132.233	Loss
TKL_IRAK_IRAK4_ST	P14598	NCF1	Q9NWZ3	IRAK4	S173	M175T	175	Missense	proximal	2	no	148.443	155.446	EPSD	GDSC;CCLE	132.233	Up-regulation
TKL_IRAK_IRAK4_ST	P14598	NCF1	Q9NWZ3	IRAK4	T179	M175T	175	Missense	distal	-4	no	125.316	144.974	EPSD	GDSC;CCLE	132.233	Gain
TKL_IRAK_IRAK4_ST	P14598	NCF1	Q9NWZ3	IRAK4	S320	Y324H	324	Missense	distal	4	no	178.601	164.652	EPSD;PhosphoSitePlus	GDSC;CCLE	132.233	Down-regulation
CK1_TTBK_TTBK1_ST	P10636	MAPT	Q5TCY1	TTBK1	S228	R222H	222	Missense	distal	-6	no	11.654	12.579	EPSD	GDSC;CCLE	7.699	Up-regulation
CK1_TTBK_TTBK1_ST	P10636	MAPT	Q5TCY1	TTBK1	S733	S739C	739	Missense	distal	6	no	12.247	10.923	EPSD	GDSC	7.699	Down-regulation
CK1_TTBK_TTBK1_ST	P10636	MAPT	Q5TCY1	TTBK1	S739	S739C	739	Missense	central	0	yes	11.793	0.000	EPSD	GDSC	7.699	Loss
CK1_TTBK_TTBK1_ST	P10636	MAPT	Q5TCY1	TTBK1	T744	S739C	739	Missense	distal	-5	no	10.882	10.640	EPSD	GDSC	7.699	Down-regulation
TKL_MLK_ZAK_MAP3K20_ST	Q9NYL2	MAP3K20	Q9NYL2	MAP3K20	T161	S155F	155	Missense	distal	-6	no	7.367	6.744	EPSD;PhosphoSitePlus	GDSC	2.674	Down-regulation
TKL_MLK_ZAK_MAP3K20_ST	Q9NYL2	MAP3K20	Q9NYL2	MAP3K20	S258	F253S	253	Missense	distal	-5	no	3.532	3.065	EPSD	GDSC	2.674	Down-regulation
TKL_MLK_ZAK_MAP3K20_ST	Q9NYL2	MAP3K20	Q9NYL2	MAP3K20	S258	L260V	260	Missense	proximal	2	no	3.532	3.691	EPSD	GDSC	2.674	Up-regulation
TKL_MLK_ZAK_MAP3K20_ST	Q9NYL2	MAP3K20	Q9NYL2	MAP3K20	T586	R590C	590	Missense	distal	4	no	2.877	2.609	EPSD	GDSC	2.674	Loss
TKL_MLK_ZAK_MAP3K20_ST	Q9NYL2	MAP3K20	Q9NYL2	MAP3K20	S764	S764N	764	Missense	central	0	yes	3.821	0.000	EPSD	GDSC	2.674	Loss
TKL_MLK_ZAK_MAP3K20_ST	O96017	CHEK2	Q9NYL2	MAP3K20	T68	S73F	73	Missense	distal	5	no	7.577	7.263	PhosphoSitePlus	GDSC;CCLE	2.674	Down-regulation
CAMK_CAMKL_NuaK_NUAK1_ST	P38936	CDKN1A	O60285	NUAK1	S137	R143Q	143	Missense	distal	6	no	5.630	5.647	EPSD	GDSC;CCLE	4.034	Up-regulation
CAMK_CAMKL_NuaK_NUAK1_ST	P38936	CDKN1A	O60285	NUAK1	S146	R143Q	143	Missense	distal	-3	no	5.858	3.642	PhosphoSitePlus	GDSC;CCLE	4.034	Loss
CAMK_CAMKL_NuaK_NUAK1_ST	P10636	MAPT	O60285	NUAK1	S214	V218G	218	Missense	distal	4	no	5.065	3.805	EPSD	GDSC	4.034	Loss
CAMK_CAMKL_NuaK_NUAK1_ST	P10636	MAPT	O60285	NUAK1	T470	A475V	475	Missense	distal	5	no	4.777	4.688	EPSD	GDSC;CCLE	4.034	Down-regulation
CAMK_CAMKL_NuaK_NUAK1_ST	P10636	MAPT	O60285	NUAK1	S637	V635I	635	Missense	proximal	-2	no	3.934	4.368	EPSD	GDSC	4.034	Gain
CAMK_CAMKL_NuaK_NUAK1_ST	P10636	MAPT	O60285	NUAK1	S641	V635I	635	Missense	distal	-6	no	5.629	5.379	EPSD	GDSC	4.034	Down-regulation
CAMK_CAMKL_NuaK_NUAK1_ST	O14974	PPP1R12A	O60285	NUAK1	S386	A383G	383	Missense	distal	-3	no	3.934	4.783	EPSD	GDSC	4.034	Gain
CAMK_CAMKL_NuaK_NUAK1_ST	O14974	PPP1R12A	O60285	NUAK1	S541	K538*	538	Missense	distal	-3	no	4.998	2.198	EPSD	GDSC	4.034	Loss
CAMK_CAMKL_NuaK_NUAK1_ST	O14974	PPP1R12A	O60285	NUAK1	S541	E545K	545	Missense	distal	4	no	4.998	5.059	EPSD	GDSC;CCLE	4.034	Up-regulation
CAMK_CAMKL_NuaK_NUAK1_ST	O14974	PPP1R12A	O60285	NUAK1	S542	K538*	538	Missense	distal	-4	no	4.567	4.370	EPSD	GDSC	4.034	Down-regulation
CAMK_CAMKL_NuaK_NUAK1_ST	O14974	PPP1R12A	O60285	NUAK1	S542	E545K	545	Missense	distal	3	no	4.567	4.608	EPSD	GDSC;CCLE	4.034	Up-regulation
CAMK_CAMKL_NuaK_NUAK1_ST	O14974	PPP1R12A	O60285	NUAK1	S610	L613S	613	Missense	distal	3	no	4.065	4.026	EPSD	GDSC;CCLE	4.034	Loss
CAMK_CAMKL_NuaK_NUAK1_ST	O14974	PPP1R12A	O60285	NUAK1	S618	T619A	619	Missense	proximal	1	no	3.997	4.070	EPSD	GDSC;CCLE	4.034	Gain
CAMK_CAMKL_NuaK_NUAK1_ST	O14974	PPP1R12A	O60285	NUAK1	S716	R720T	720	Missense	distal	4	no	4.110	4.310	EPSD	GDSC;CCLE	4.034	Up-regulation
CAMK_CAMKL_NuaK_NUAK1_ST	O14974	PPP1R12A	O60285	NUAK1	S716	R715L	715	Missense	proximal	-1	no	4.110	4.170	EPSD	GDSC;CCLE	4.034	Up-regulation
CAMK_CAMKL_NuaK_NUAK1_ST	P55212	CASP6	O60285	NUAK1	S79	N73T	73	Missense	distal	-6	no	4.402	4.313	EPSD	GDSC	4.034	Down-regulation
CAMK_CAMKL_NuaK_NUAK1_ST	P55212	CASP6	O60285	NUAK1	S79	S79L	79	Missense	central	0	yes	4.402	0.000	EPSD	GDSC	4.034	Loss
CAMK_CAMKL_NuaK_NUAK1_ST	P04637	TP53	O60285	NUAK1	S392	G389W	389	Missense	distal	-3	no	6.382	5.373	PhosphoSitePlus;EPSD	GDSC;CCLE	4.034	Down-regulation
CAMK_CAMKL_NuaK_NUAK1_ST	O95835	LATS1	O60285	NUAK1	S216	I220V	220	Missense	distal	4	no	4.999	5.802	EPSD	GDSC;CCLE	4.034	Up-regulation
CAMK_CAMKL_NuaK_NUAK1_ST	O95835	LATS1	O60285	NUAK1	S596	E594K	594	Missense	proximal	-2	no	5.604	5.868	EPSD	GDSC;CCLE	4.034	Up-regulation
CAMK_CAMKL_NuaK_NUAK1_ST	O95835	LATS1	O60285	NUAK1	S633	Q637*	637	Missense	distal	4	no	4.312	4.691	EPSD	GDSC	4.034	Up-regulation
Other_ULK_ULK_ULK2_ST	O15027	SEC16A	Q8IYT8	ULK2	S118	S122G	122	Missense	distal	4	no	3.778	3.938	EPSD	GDSC	3.097	Up-regulation
Other_ULK_ULK_ULK2_ST	O15027	SEC16A	Q8IYT8	ULK2	S122	P128S	128	Missense	distal	6	no	3.942	3.975	EPSD	GDSC;CCLE	3.097	Up-regulation
Other_ULK_ULK_ULK2_ST	O15027	SEC16A	Q8IYT8	ULK2	S122	S122G	122	Missense	central	0	yes	3.942	0.000	EPSD	GDSC	3.097	Loss
Other_ULK_ULK_ULK2_ST	O15027	SEC16A	Q8IYT8	ULK2	S136	L139R	139	Missense	distal	3	no	4.720	4.753	EPSD	GDSC;CCLE	3.097	Up-regulation
Other_ULK_ULK_ULK2_ST	O15027	SEC16A	Q8IYT8	ULK2	S179	P183S	183	Missense	distal	4	no	4.491	4.371	EPSD	GDSC	3.097	Down-regulation
Other_ULK_ULK_ULK2_ST	O15027	SEC16A	Q8IYT8	ULK2	S179	G176R	176	Missense	distal	-3	no	4.491	5.170	EPSD	GDSC;CCLE	3.097	Up-regulation
Other_ULK_ULK_ULK2_ST	O15027	SEC16A	Q8IYT8	ULK2	T337	H339R	339	Missense	proximal	2	no	3.733	3.993	EPSD	GDSC;CCLE	3.097	Up-regulation
Other_ULK_ULK_ULK2_ST	O15027	SEC16A	Q8IYT8	ULK2	T337	S342N	342	Missense	distal	5	no	3.733	3.755	EPSD	GDSC;CCLE	3.097	Up-regulation
Other_ULK_ULK_ULK2_ST	O15027	SEC16A	Q8IYT8	ULK2	T337	A333S	333	Missense	distal	-4	no	3.733	3.531	EPSD	GDSC;CCLE	3.097	Down-regulation
Other_ULK_ULK_ULK2_ST	O15027	SEC16A	Q8IYT8	ULK2	S346	H339R	339	Missense	distal	-7	no	3.321	3.297	EPSD	GDSC;CCLE	3.097	Down-regulation
Other_ULK_ULK_ULK2_ST	O15027	SEC16A	Q8IYT8	ULK2	S346	S342N	342	Missense	distal	-4	no	3.321	3.466	EPSD	GDSC;CCLE	3.097	Up-regulation
Other_ULK_ULK_ULK2_ST	O15027	SEC16A	Q8IYT8	ULK2	S356	P361H	361	Missense	distal	5	no	3.295	3.394	EPSD	GDSC;CCLE	3.097	Up-regulation
Other_ULK_ULK_ULK2_ST	O15027	SEC16A	Q8IYT8	ULK2	S358	P361H	361	Missense	distal	3	no	3.930	3.977	EPSD	GDSC;CCLE	3.097	Up-regulation
Other_ULK_ULK_ULK2_ST	O15027	SEC16A	Q8IYT8	ULK2	S668	S672P	672	Missense	distal	4	no	8.682	8.802	EPSD	GDSC;CCLE	3.097	Up-regulation
Other_ULK_ULK_ULK2_ST	O15027	SEC16A	Q8IYT8	ULK2	S668	S670P	670	Missense	proximal	2	no	8.682	8.896	EPSD	GDSC	3.097	Up-regulation
Other_ULK_ULK_ULK2_ST	O15027	SEC16A	Q8IYT8	ULK2	S771	S771N	771	Missense	central	0	yes	3.216	0.000	EPSD	GDSC;CCLE	3.097	Loss
Other_ULK_ULK_ULK2_ST	O15027	SEC16A	Q8IYT8	ULK2	T812	A815T	815	Missense	distal	3	no	3.141	3.037	EPSD	GDSC	3.097	Loss
Other_ULK_ULK_ULK2_ST	O15027	SEC16A	Q8IYT8	ULK2	T819	R822K	822	Missense	distal	3	no	3.672	3.694	EPSD	GDSC;CCLE	3.097	Up-regulation
Other_ULK_ULK_ULK2_ST	O15027	SEC16A	Q8IYT8	ULK2	T819	A815T	815	Missense	distal	-4	no	3.672	3.798	EPSD	GDSC	3.097	Up-regulation
Other_ULK_ULK_ULK2_ST	O15027	SEC16A	Q8IYT8	ULK2	S1044	E1041K	1041	Missense	distal	-3	no	3.054	3.179	EPSD	GDSC;CCLE	3.097	Gain
Other_ULK_ULK_ULK2_ST	O15027	SEC16A	Q8IYT8	ULK2	S1236	S1232N	1232	Missense	distal	-4	no	3.523	3.668	EPSD	GDSC	3.097	Up-regulation
Other_ULK_ULK_ULK2_ST	O15027	SEC16A	Q8IYT8	ULK2	S1236	P1238L	1238	Missense	proximal	2	no	3.523	3.084	EPSD	GDSC	3.097	Loss
Other_ULK_ULK_ULK2_ST	O15027	SEC16A	Q8IYT8	ULK2	S1859	E1866Q	1866	Missense	distal	7	no	3.477	3.390	EPSD	GDSC;CCLE	3.097	Down-regulation
Other_ULK_ULK_ULK2_ST	O15027	SEC16A	Q8IYT8	ULK2	S1903	P1900L	1900	Missense	distal	-3	no	3.218	3.882	EPSD	GDSC;CCLE	3.097	Up-regulation
Other_ULK_ULK_ULK2_ST	O15027	SEC16A	Q8IYT8	ULK2	S1903	T1898R	1898	Missense	distal	-5	no	3.218	3.205	EPSD	GDSC;CCLE	3.097	Down-regulation
Other_ULK_ULK_ULK2_ST	O15027	SEC16A	Q8IYT8	ULK2	S1903	T1898M	1898	Missense	distal	-5	no	3.218	3.283	EPSD	GDSC;CCLE	3.097	Up-regulation
Other_ULK_ULK_ULK2_ST	O15027	SEC16A	Q8IYT8	ULK2	S1903	S1903F	1903	Missense	central	0	yes	3.218	0.000	EPSD	GDSC;CCLE	3.097	Loss
Other_ULK_ULK_ULK2_ST	O15027	SEC16A	Q8IYT8	ULK2	S1903	Q1899*	1899	Missense	distal	-4	no	3.218	2.773	EPSD	GDSC	3.097	Loss
Other_ULK_ULK_ULK2_ST	O15027	SEC16A	Q8IYT8	ULK2	S1905	Q1899*	1899	Missense	distal	-6	no	2.732	3.130	EPSD	GDSC	3.097	Gain
Other_ULK_ULK_ULK2_ST	A2RUS2	DENND3	Q8IYT8	ULK2	S472	V471G	471	Missense	proximal	-1	no	9.056	8.819	PhosphoSitePlus;EPSD	GDSC	3.097	Down-regulation
Other_ULK_ULK_ULK2_ST	A2RUS2	DENND3	Q8IYT8	ULK2	S472	R468C	468	Missense	distal	-4	no	9.056	9.114	PhosphoSitePlus;EPSD	GDSC	3.097	Up-regulation
Other_ULK_ULK_ULK2_ST	A2RUS2	DENND3	Q8IYT8	ULK2	S490	R492Q	492	Missense	proximal	2	no	9.018	8.239	EPSD;PhosphoSitePlus	GDSC	3.097	Down-regulation
Other_PEK_HRI_EIF2AK1_ST	P05198	EIF2S1	Q9BQI3	EIF2AK1	S49	G44D	44	Missense	distal	-5	no	7.554	7.511	EPSD;PhosphoSitePlus	CCLE	2.464	Down-regulation
AGC_PKC_PKCd_PRKCD_ST	Q9UQL6	HDAC5	Q05655	PRKCD	S7	G9R	9	Missense	proximal	2	no	2.264	8.595	EPSD	CCLE	7.604	Gain
AGC_PKC_PKCd_PRKCD_ST	Q9UQL6	HDAC5	Q05655	PRKCD	S24	S24P	24	Missense	central	0	yes	10.387	0.000	EPSD	CCLE	7.604	Loss
AGC_PKC_PKCd_PRKCD_ST	Q9UQL6	HDAC5	Q05655	PRKCD	S480	T479I	479	Missense	proximal	-1	no	8.226	8.137	EPSD	CCLE	7.604	Down-regulation
AGC_PKC_PKCd_PRKCD_ST	Q9UQL6	HDAC5	Q05655	PRKCD	S713	R710G	710	Missense	distal	-3	no	7.680	2.471	EPSD	CCLE	7.604	Loss
AGC_PKC_PKCd_PRKCD_ST	Q9UQL6	HDAC5	Q05655	PRKCD	S1108	E1113Q	1113	Missense	distal	5	no	13.327	13.370	EPSD	CCLE	7.604	Up-regulation
AGC_PKC_PKCd_PRKCD_ST	Q9UQL6	HDAC5	Q05655	PRKCD	S1108	S1108G	1108	Missense	central	0	yes	13.327	0.000	EPSD	CCLE	7.604	Loss
AGC_PKC_PKCd_PRKCD_ST	P10415	BCL2	Q05655	PRKCD	S24	L23R	23	Missense	proximal	-1	no	12.548	12.739	EPSD	CCLE	7.604	Up-regulation
AGC_PKC_PKCd_PRKCD_ST	P10415	BCL2	Q05655	PRKCD	S70	Q73H	73	Missense	distal	3	no	8.616	8.805	PhosphoSitePlus	CCLE	7.604	Up-regulation
AGC_PKC_PKCd_PRKCD_ST	P53004	BLVRA	Q05655	PRKCD	S21	R18Q	18	Missense	distal	-3	no	15.400	10.242	EPSD;PhosphoSitePlus	CCLE	7.604	Down-regulation
AGC_PKC_PKCd_PRKCD_ST	P35611	ADD1	Q05655	PRKCD	S353	K348T	348	Missense	distal	-5	no	8.812	8.538	EPSD	CCLE	7.604	Down-regulation
AGC_PKC_PKCd_PRKCD_ST	P35611	ADD1	Q05655	PRKCD	S355	K348T	348	Missense	distal	-7	no	7.607	7.589	EPSD	CCLE	7.604	Loss
AGC_PKC_PKCd_PRKCD_ST	P35611	ADD1	Q05655	PRKCD	S404	K403R	403	Missense	proximal	-1	no	12.122	12.128	EPSD	CCLE	7.604	Up-regulation
AGC_PKC_PKCd_PRKCD_ST	P35611	ADD1	Q05655	PRKCD	S408	K403R	403	Missense	distal	-5	no	11.745	11.771	EPSD	CCLE	7.604	Up-regulation
AGC_PKC_PKCd_PRKCD_ST	P35611	ADD1	Q05655	PRKCD	S669	A664V	664	Missense	distal	-5	no	8.801	8.715	EPSD	CCLE	7.604	Down-regulation
AGC_PKC_PKCd_PRKCD_ST	P35611	ADD1	Q05655	PRKCD	S669	R666S	666	Missense	distal	-3	no	8.801	4.226	EPSD	CCLE	7.604	Loss
AGC_PKC_PKCd_PRKCD_ST	P35611	ADD1	Q05655	PRKCD	S669	S669R	669	Missense	central	0	yes	8.801	0.000	EPSD	CCLE	7.604	Loss
AGC_PKC_PKCd_PRKCD_ST	P35611	ADD1	Q05655	PRKCD	T671	S669R	669	Missense	proximal	-2	no	3.342	8.190	EPSD	CCLE	7.604	Gain
AGC_PKC_PKCd_PRKCD_ST	P14598	NCF1	Q05655	PRKCD	S320	R326H	326	Missense	distal	6	no	9.608	9.558	EPSD;PhosphoSitePlus	CCLE	7.604	Down-regulation
AGC_PKC_PKCd_PRKCD_ST	P14598	NCF1	Q05655	PRKCD	S328	R326H	326	Missense	proximal	-2	no	17.699	12.724	EPSD;PhosphoSitePlus	CCLE	7.604	Down-regulation
AGC_PKC_PKCd_PRKCD_ST	P14598	NCF1	Q05655	PRKCD	T356	R354L	354	Missense	proximal	-2	no	12.051	5.918	EPSD	CCLE	7.604	Loss
AGC_PKC_PKCd_PRKCD_ST	P14598	NCF1	Q05655	PRKCD	T356	Q357H	357	Missense	proximal	1	no	12.051	12.047	EPSD	CCLE	7.604	Down-regulation
AGC_PKC_PKCd_PRKCD_ST	Q16206	ENOX2	Q05655	PRKCD	S240	L236M	236	Missense	distal	-4	no	9.670	9.671	EPSD	CCLE	7.604	Up-regulation
AGC_PKC_PKCd_PRKCD_ST	O76090	BEST1	Q05655	PRKCD	S16	R19W	19	Missense	distal	3	no	9.342	7.919	EPSD	CCLE	7.604	Down-regulation
AGC_PKC_PKCd_PRKCD_ST	O76090	BEST1	Q05655	PRKCD	T536	E538A	538	Missense	proximal	2	no	8.369	10.078	EPSD	CCLE	7.604	Up-regulation
AGC_PKC_PKCd_PRKCD_ST	Q9H257	CARD9	Q05655	PRKCD	T231	K233T	233	Missense	proximal	2	no	16.196	11.118	PhosphoSitePlus	CCLE	7.604	Down-regulation
AGC_PKC_PKCd_PRKCD_ST	Q9H257	CARD9	Q05655	PRKCD	S303	R305C	305	Missense	proximal	2	no	9.149	2.270	EPSD	CCLE	7.604	Loss
AGC_PKC_PKCd_PRKCD_ST	Q05655	PRKCD	Q05655	PRKCD	S299	N292Y	292	Missense	distal	-7	no	13.252	13.248	EPSD;PhosphoSitePlus	CCLE	7.604	Down-regulation
AGC_PKC_PKCd_PRKCD_ST	Q05655	PRKCD	Q05655	PRKCD	S506	R504Q	504	Missense	proximal	-2	no	9.588	4.153	EPSD	CCLE	7.604	Loss
AGC_PKC_PKCd_PRKCD_ST	Q05655	PRKCD	Q05655	PRKCD	S559	R561H	561	Missense	proximal	2	no	8.200	2.639	EPSD	CCLE	7.604	Loss
AGC_PKC_PKCd_PRKCD_ST	Q05655	PRKCD	Q05655	PRKCD	S626	P627L	627	Missense	proximal	1	no	13.703	13.628	EPSD	CCLE	7.604	Down-regulation
AGC_PKC_PKCd_PRKCD_ST	Q05655	PRKCD	Q05655	PRKCD	S631	P627L	627	Missense	distal	-4	no	7.637	7.776	EPSD	CCLE	7.604	Up-regulation
AGC_PKC_PKCd_PRKCD_ST	P13796	LCP1	Q05655	PRKCD	T503	R500I	500	Missense	distal	-3	no	9.340	3.699	EPSD	CCLE	7.604	Loss
AGC_PKC_PKCd_PRKCD_ST	Q9HBA0	TRPV4	Q05655	PRKCD	S134	P132A	132	Missense	proximal	-2	no	9.176	8.829	EPSD	CCLE	7.604	Down-regulation
AGC_PKC_PKCd_PRKCD_ST	Q13501	SQSTM1	Q05655	PRKCD	S283	K281R	281	Missense	proximal	-2	no	7.387	8.632	EPSD	CCLE	7.604	Gain
AGC_PKC_PKCd_PRKCD_ST	Q13501	SQSTM1	Q05655	PRKCD	S284	K281R	281	Missense	distal	-3	no	8.808	9.843	EPSD	CCLE	7.604	Up-regulation
AGC_PKC_PKCd_PRKCD_ST	P05787	KRT8	Q05655	PRKCD	S456	S451F	451	Missense	distal	-5	no	9.616	9.506	EPSD	CCLE	7.604	Down-regulation
AGC_PKC_PKCd_PRKCD_ST	P05787	KRT8	Q05655	PRKCD	S457	S451F	451	Missense	distal	-6	no	13.673	13.878	EPSD	CCLE	7.604	Up-regulation
AGC_PKC_PKCd_PRKCD_ST	Q02297	NRG1	Q05655	PRKCD	S435	T430N	430	Missense	distal	-5	no	9.417	9.313	EPSD	CCLE	7.604	Down-regulation
AGC_PKC_PKCd_PRKCD_ST	Q02297	NRG1	Q05655	PRKCD	S444	P445L	445	Missense	proximal	1	no	7.895	7.820	EPSD	CCLE	7.604	Down-regulation
AGC_PKC_PKCd_PRKCD_ST	Q02297	NRG1	Q05655	PRKCD	S619	Q625R	625	Missense	distal	6	no	7.893	7.940	EPSD	CCLE	7.604	Up-regulation
AGC_PKC_PKCd_PRKCD_ST	Q14247	CTTN	Q05655	PRKCD	S109	S106L	106	Missense	distal	-3	no	7.847	7.235	EPSD	CCLE	7.604	Loss
AGC_PKC_PKCd_PRKCD_ST	Q14247	CTTN	Q05655	PRKCD	S277	G271R	271	Missense	distal	-6	no	9.333	8.941	EPSD	CCLE	7.604	Down-regulation
AGC_PKC_PKCd_PRKCD_ST	Q14247	CTTN	Q05655	PRKCD	S282	G286E	286	Missense	distal	4	no	8.343	8.408	EPSD	CCLE	7.604	Up-regulation
AGC_PKC_PKCd_PRKCD_ST	P98082	DAB2	Q05655	PRKCD	S390	N387S	387	Missense	distal	-3	no	7.200	7.765	EPSD	CCLE	7.604	Gain
AGC_PKC_PKCd_PRKCD_ST	P98082	DAB2	Q05655	PRKCD	S423	Q421R	421	Missense	proximal	-2	no	3.198	8.633	EPSD	CCLE	7.604	Gain
AGC_PKC_PKCd_PRKCD_ST	P98082	DAB2	Q05655	PRKCD	S742	S742F	742	Missense	central	0	yes	7.927	0.000	EPSD	CCLE	7.604	Loss
AGC_PKC_PKCd_PRKCD_ST	Q15139	PRKD1	Q05655	PRKCD	S420	M424V	424	Missense	distal	4	no	11.256	11.246	EPSD	CCLE	7.604	Down-regulation
AGC_PKC_PKCd_PRKCD_ST	Q15139	PRKD1	Q05655	PRKCD	S421	M424V	424	Missense	distal	3	no	10.023	9.997	EPSD	CCLE	7.604	Down-regulation
AGC_PKC_PKCd_PRKCD_ST	P28329	CHAT	Q05655	PRKCD	S464	A471V	471	Missense	distal	7	no	9.423	9.385	EPSD	CCLE	7.604	Down-regulation
AGC_PKC_PKCd_PRKCD_ST	P28329	CHAT	Q05655	PRKCD	S473	A471V	471	Missense	proximal	-2	no	8.924	8.293	EPSD	CCLE	7.604	Down-regulation
AGC_PKC_PKCd_PRKCD_ST	P28329	CHAT	Q05655	PRKCD	S473	P480F	480	Missense	distal	7	no	8.924	8.905	EPSD	CCLE	7.604	Down-regulation
AGC_PKC_PKCd_PRKCD_ST	P28329	CHAT	Q05655	PRKCD	S558	A557E	557	Missense	proximal	-1	no	9.671	9.643	EPSD	CCLE	7.604	Down-regulation
AGC_PKC_PKCd_PRKCD_ST	P28329	CHAT	Q05655	PRKCD	S594	V591L	591	Missense	distal	-3	no	9.664	9.278	EPSD	CCLE	7.604	Down-regulation
AGC_PKC_PKCd_PRKCD_ST	P13498	CYBA	Q05655	PRKCD	S168	R164H	164	Missense	distal	-4	no	10.563	10.856	EPSD	CCLE	7.604	Up-regulation
AGC_PKC_PKCd_PRKCD_ST	P13498	CYBA	Q05655	PRKCD	S168	R164C	164	Missense	distal	-4	no	10.563	10.999	EPSD	CCLE	7.604	Up-regulation
AGC_PKC_PKCd_PRKCD_ST	P13498	CYBA	Q05655	PRKCD	S168	E162V	162	Missense	distal	-6	no	10.563	10.638	EPSD	CCLE	7.604	Up-regulation
AGC_PKC_PKCd_PRKCD_ST	Q8TCU6	PREX1	Q05655	PRKCD	S1001	S1001F	1001	Missense	central	0	yes	11.614	0.000	EPSD	CCLE	7.604	Loss
AGC_PKC_PKCd_PRKCD_ST	Q8TCU6	PREX1	Q05655	PRKCD	S1359	E1357D	1357	Missense	proximal	-2	no	8.272	8.946	EPSD	CCLE	7.604	Up-regulation
AGC_PKC_PKCd_PRKCD_ST	P78536	ADAM17	Q05655	PRKCD	S608	R610H	610	Missense	proximal	2	no	13.823	8.262	EPSD	CCLE	7.604	Down-regulation
AGC_PKC_PKCd_PRKCD_ST	P35568	IRS1	Q05655	PRKCD	S24	L19R	19	Missense	distal	-5	no	11.075	11.505	EPSD	CCLE	7.604	Up-regulation
AGC_PKC_PKCd_PRKCD_ST	P35568	IRS1	Q05655	PRKCD	S268	S273L	273	Missense	distal	5	no	8.493	8.303	EPSD	CCLE	7.604	Down-regulation
AGC_PKC_PKCd_PRKCD_ST	P35568	IRS1	Q05655	PRKCD	S270	S273L	273	Missense	distal	3	no	9.706	9.419	EPSD	CCLE	7.604	Down-regulation
AGC_PKC_PKCd_PRKCD_ST	P35568	IRS1	Q05655	PRKCD	S307	A314D	314	Missense	distal	7	no	8.043	8.026	EPSD;PhosphoSitePlus	CCLE	7.604	Down-regulation
AGC_PKC_PKCd_PRKCD_ST	P35568	IRS1	Q05655	PRKCD	S307	R304H	304	Missense	distal	-3	no	8.043	3.788	EPSD;PhosphoSitePlus	CCLE	7.604	Loss
AGC_PKC_PKCd_PRKCD_ST	P35568	IRS1	Q05655	PRKCD	S307	R302Q	302	Missense	distal	-5	no	8.043	7.692	EPSD;PhosphoSitePlus	CCLE	7.604	Down-regulation
AGC_PKC_PKCd_PRKCD_ST	P35568	IRS1	Q05655	PRKCD	T525	P532S	532	Missense	distal	7	no	10.973	11.001	EPSD	CCLE	7.604	Up-regulation
AGC_PKC_PKCd_PRKCD_ST	P35568	IRS1	Q05655	PRKCD	S792	S795Y	795	Missense	distal	3	no	8.515	8.038	EPSD	CCLE	7.604	Down-regulation
AGC_PKC_PKCd_PRKCD_ST	P35568	IRS1	Q05655	PRKCD	S792	L791P	791	Missense	proximal	-1	no	8.515	8.591	EPSD	CCLE	7.604	Up-regulation
AGC_PKC_PKCd_PRKCD_ST	P35568	IRS1	Q05655	PRKCD	S795	S795Y	795	Missense	central	0	yes	7.681	0.000	EPSD	CCLE	7.604	Loss
AGC_PKC_PKCd_PRKCD_ST	P35568	IRS1	Q05655	PRKCD	S795	L791P	791	Missense	distal	-4	no	7.681	7.542	EPSD	CCLE	7.604	Loss
AGC_PKC_PKCd_PRKCD_ST	P35568	IRS1	Q05655	PRKCD	S1100	S1105F	1105	Missense	distal	5	no	12.851	12.640	EPSD	CCLE	7.604	Down-regulation
AGC_PKC_PKCd_PRKCD_ST	P35568	IRS1	Q05655	PRKCD	S1101	S1105F	1105	Missense	distal	4	no	9.221	9.077	EPSD	CCLE	7.604	Down-regulation
AGC_PKC_PKCd_PRKCD_ST	P35568	IRS1	Q05655	PRKCD	S1142	E1136K	1136	Missense	distal	-6	no	14.459	14.040	EPSD	CCLE	7.604	Down-regulation
AGC_PKC_PKCd_PRKCD_ST	P35568	IRS1	Q05655	PRKCD	S1143	E1136K	1136	Missense	distal	-7	no	8.725	8.748	EPSD	CCLE	7.604	Up-regulation
AGC_PKC_PKCd_PRKCD_ST	P11413	G6PD	Q05655	PRKCD	T76	S73Y	73	Missense	distal	-3	no	8.054	6.751	EPSD	CCLE	7.604	Loss
AGC_PKC_PKCd_PRKCD_ST	P53671	LIMK2	Q05655	PRKCD	T505	N509S	509	Missense	distal	4	no	8.530	8.713	EPSD	CCLE	7.604	Up-regulation
AGC_PKC_PKCd_PRKCD_ST	P10588	NR2F6	Q05655	PRKCD	S83	I84T	84	Missense	proximal	1	no	15.568	15.655	PhosphoSitePlus	CCLE	7.604	Up-regulation
AGC_PKC_PKCd_PRKCD_ST	P10588	NR2F6	Q05655	PRKCD	S83	F79L	79	Missense	distal	-4	no	15.568	15.598	PhosphoSitePlus	CCLE	7.604	Up-regulation
AGC_PKC_PKCd_PRKCD_ST	P40189	IL6ST	Q05655	PRKCD	S820	Q817R	817	Missense	distal	-3	no	2.894	8.051	EPSD	CCLE	7.604	Gain
AGC_PKC_PKCd_PRKCD_ST	P23396	RPS3	Q05655	PRKCD	S6	V3A	3	Missense	distal	-3	no	9.892	10.353	PhosphoSitePlus;EPSD	CCLE	7.604	Up-regulation
AGC_PKC_PKCd_PRKCD_ST	O14939	PLD2	Q05655	PRKCD	S155	R149G	149	Missense	distal	-6	no	8.536	8.928	EPSD	CCLE	7.604	Up-regulation
AGC_PKC_PKCd_PRKCD_ST	O14939	PLD2	Q05655	PRKCD	T488	S484F	484	Missense	distal	-4	no	7.541	7.671	EPSD	CCLE	7.604	Gain
AGC_PKC_PKCd_PRKCD_ST	O14939	PLD2	Q05655	PRKCD	S493	R490C	490	Missense	distal	-3	no	9.471	4.151	EPSD	CCLE	7.604	Loss
AGC_PKC_PKCd_PRKCD_ST	O14939	PLD2	Q05655	PRKCD	S814	R816W	816	Missense	proximal	2	no	10.890	4.217	EPSD	CCLE	7.604	Loss
AGC_PKC_PKCd_PRKCD_ST	O95817	BAG3	Q05655	PRKCD	S224	Q222R	222	Missense	proximal	-2	no	2.597	8.031	EPSD	CCLE	7.604	Gain
AGC_PKC_PKCd_PRKCD_ST	O95817	BAG3	Q05655	PRKCD	S264	P259L	259	Missense	distal	-5	no	8.309	8.162	EPSD	CCLE	7.604	Down-regulation
AGC_PKC_PKCd_PRKCD_ST	O95817	BAG3	Q05655	PRKCD	S269	A273T	273	Missense	distal	4	no	7.782	7.813	EPSD	CCLE	7.604	Up-regulation
AGC_PKC_PKCd_PRKCD_ST	O95817	BAG3	Q05655	PRKCD	S279	A273T	273	Missense	distal	-6	no	9.528	9.451	EPSD	CCLE	7.604	Down-regulation
AGC_PKC_PKCd_PRKCD_ST	O95817	BAG3	Q05655	PRKCD	S279	E277V	277	Missense	proximal	-2	no	9.528	10.313	EPSD	CCLE	7.604	Up-regulation
AGC_PKC_PKCd_PRKCD_ST	O95817	BAG3	Q05655	PRKCD	S284	E277V	277	Missense	distal	-7	no	8.686	8.683	EPSD	CCLE	7.604	Down-regulation
AGC_PKC_PKCd_PRKCD_ST	O95817	BAG3	Q05655	PRKCD	S284	S289P	289	Missense	distal	5	no	8.686	8.718	EPSD	CCLE	7.604	Up-regulation
AGC_PKC_PKCd_PRKCD_ST	O95817	BAG3	Q05655	PRKCD	S359	S359F	359	Missense	central	0	yes	8.570	0.000	EPSD	CCLE	7.604	Loss
AGC_PKC_PKCd_PRKCD_ST	P29353	SHC1	Q05655	PRKCD	S139	T145M	145	Missense	distal	6	no	9.770	9.743	EPSD	CCLE	7.604	Down-regulation
AGC_PKC_PKCd_PRKCD_ST	P29353	SHC1	Q05655	PRKCD	T206	A202S	202	Missense	distal	-4	no	10.677	10.595	EPSD	CCLE	7.604	Down-regulation
AGC_PKC_PKCd_PRKCD_ST	Q15717	ELAVL1	Q05655	PRKCD	S221	G224D	224	Missense	distal	3	no	8.144	8.177	EPSD;PhosphoSitePlus	CCLE	7.604	Up-regulation
AGC_PKC_PKCd_PRKCD_ST	P30273	FCER1G	Q05655	PRKCD	S69	V64A	64	Missense	distal	-5	no	9.696	9.783	PhosphoSitePlus	CCLE	7.604	Up-regulation
AGC_PKC_PKCd_PRKCD_ST	P30273	FCER1G	Q05655	PRKCD	S69	T70A	70	Missense	proximal	1	no	9.696	9.634	PhosphoSitePlus	CCLE	7.604	Down-regulation
AGC_PKC_PKCd_PRKCD_ST	P49841	GSK3B	Q05655	PRKCD	S147	T152M	152	Missense	distal	5	no	8.102	7.940	EPSD	CCLE	7.604	Down-regulation
AGC_PKC_PKCd_PRKCD_ST	P49841	GSK3B	Q05655	PRKCD	S203	K205R	205	Missense	proximal	2	no	6.677	7.855	EPSD	CCLE	7.604	Gain
AGC_PKC_PKCd_PRKCD_ST	O00429	DNM1L	Q05655	PRKCD	S563	S563N	563	Missense	central	0	yes	9.004	0.000	EPSD	CCLE	7.604	Loss
AGC_PKC_PKCd_PRKCD_ST	Q09472	EP300	Q05655	PRKCD	S89	M95T	95	Missense	distal	6	no	9.743	9.771	PhosphoSitePlus	CCLE	7.604	Up-regulation
AGC_PKC_PKCd_PRKCD_ST	Q09472	EP300	Q05655	PRKCD	T1135	C1142Y	1142	Missense	distal	7	no	12.232	12.233	EPSD	CCLE	7.604	Up-regulation
AGC_PKC_PKCd_PRKCD_ST	Q09472	EP300	Q05655	PRKCD	S1295	F1288L	1288	Missense	distal	-7	no	12.842	12.841	EPSD	CCLE	7.604	Down-regulation
AGC_PKC_PKCd_PRKCD_ST	Q09472	EP300	Q05655	PRKCD	S1643	S1650F	1650	Missense	distal	7	no	9.055	9.007	EPSD	CCLE	7.604	Down-regulation
AGC_PKC_PKCd_PRKCD_ST	Q09472	EP300	Q05655	PRKCD	S1730	R1737H	1737	Missense	distal	7	no	7.716	7.629	EPSD	CCLE	7.604	Down-regulation
AGC_PKC_PKCd_PRKCD_ST	Q09472	EP300	Q05655	PRKCD	S1734	R1737H	1737	Missense	distal	3	no	13.068	12.180	EPSD	CCLE	7.604	Down-regulation
AGC_PKC_PKCd_PRKCD_ST	Q09472	EP300	Q05655	PRKCD	S2315	R2308H	2308	Missense	distal	-7	no	9.233	9.216	EPSD	CCLE	7.604	Down-regulation
AGC_PKC_PKCd_PRKCD_ST	O15350	TP73	Q05655	PRKCD	S326	A320T	320	Missense	distal	-6	no	9.334	9.257	EPSD	CCLE	7.604	Down-regulation
AGC_PKC_PKCd_PRKCD_ST	O15350	TP73	Q05655	PRKCD	S388	Q392R	392	Missense	distal	4	no	7.254	7.842	EPSD	CCLE	7.604	Gain
AGC_PKC_PKCd_PRKCD_ST	P12931	SRC	Q05655	PRKCD	S12	L18R	18	Missense	distal	6	no	14.804	14.867	PhosphoSitePlus	CCLE	7.604	Up-regulation
AGC_PKC_PKCd_PRKCD_ST	P12931	SRC	Q05655	PRKCD	S17	L18R	18	Missense	proximal	1	no	14.401	14.550	EPSD	CCLE	7.604	Up-regulation
AGC_PKC_PKCd_PRKCD_ST	P52757	CHN2	Q05655	PRKCD	S85	P89A	89	Missense	distal	4	no	13.564	13.458	EPSD	CCLE	7.604	Down-regulation
AGC_PKC_PKCd_PRKCD_ST	P52757	CHN2	Q05655	PRKCD	S167	T160A	160	Missense	distal	-7	no	11.819	11.818	EPSD	CCLE	7.604	Down-regulation
AGC_PKC_PKCd_PRKCD_ST	Q8IV61	RASGRP3	Q05655	PRKCD	S385	P392S	392	Missense	distal	7	no	8.525	8.553	EPSD	CCLE	7.604	Up-regulation
AGC_PKC_PKCd_PRKCD_ST	Q8IV61	RASGRP3	Q05655	PRKCD	S597	L593P	593	Missense	distal	-4	no	9.497	9.359	EPSD	CCLE	7.604	Down-regulation
AGC_PKC_PKCd_PRKCD_ST	Q8IV61	RASGRP3	Q05655	PRKCD	S598	L593P	593	Missense	distal	-5	no	7.876	8.023	EPSD	CCLE	7.604	Up-regulation
CAMK_PIM_PIM2_ST	P52789	HK2	Q9P1W9	PIM2	S408	G414S	414	Missense	distal	6	no	4.803	4.685	EPSD	CCLE	4.322	Down-regulation
CAMK_PIM_PIM2_ST	P52789	HK2	Q9P1W9	PIM2	T409	G414S	414	Missense	distal	5	no	4.326	4.495	EPSD	CCLE	4.322	Up-regulation
CAMK_PIM_PIM2_ST	P38936	CDKN1A	Q9P1W9	PIM2	S31	P24T	24	Missense	distal	-7	no	4.430	4.083	EPSD	CCLE	4.322	Loss
CAMK_PIM_PIM2_ST	P35568	IRS1	Q9P1W9	PIM2	S270	S273L	273	Missense	distal	3	no	5.498	5.631	EPSD	CCLE	4.322	Up-regulation
CAMK_PIM_PIM2_ST	P35568	IRS1	Q9P1W9	PIM2	S272	S273L	273	Missense	proximal	1	no	5.034	5.331	EPSD	CCLE	4.322	Up-regulation
CAMK_PIM_PIM2_ST	P35568	IRS1	Q9P1W9	PIM2	S307	A314D	314	Missense	distal	7	no	5.185	5.447	EPSD	CCLE	4.322	Up-regulation
CAMK_PIM_PIM2_ST	P35568	IRS1	Q9P1W9	PIM2	S307	R304H	304	Missense	distal	-3	no	5.185	4.007	EPSD	CCLE	4.322	Loss
CAMK_PIM_PIM2_ST	P35568	IRS1	Q9P1W9	PIM2	S307	R302Q	302	Missense	distal	-5	no	5.185	1.961	EPSD	CCLE	4.322	Loss
CAMK_PIM_PIM2_ST	P35568	IRS1	Q9P1W9	PIM2	S312	A314D	314	Missense	proximal	2	no	5.068	5.118	EPSD	CCLE	4.322	Up-regulation
CAMK_PIM_PIM2_ST	P35568	IRS1	Q9P1W9	PIM2	S527	P532S	532	Missense	distal	5	no	4.512	4.613	EPSD	CCLE	4.322	Up-regulation
CAMK_PIM_PIM2_ST	P35568	IRS1	Q9P1W9	PIM2	T533	P532S	532	Missense	proximal	-1	no	4.687	4.515	EPSD	CCLE	4.322	Down-regulation
CAMK_PIM_PIM2_ST	P35568	IRS1	Q9P1W9	PIM2	S736	V738M	738	Missense	proximal	2	no	4.364	4.327	EPSD	CCLE	4.322	Down-regulation
CAMK_PIM_PIM2_ST	P35568	IRS1	Q9P1W9	PIM2	T938	K943N	943	Missense	distal	5	no	4.540	4.499	EPSD	CCLE	4.322	Down-regulation
CAMK_PIM_PIM2_ST	P35568	IRS1	Q9P1W9	PIM2	S1101	S1105F	1105	Missense	distal	4	no	12.128	12.953	PhosphoSitePlus	CCLE	4.322	Up-regulation
CAMK_PIM_PIM2_ST	P35568	IRS1	Q9P1W9	PIM2	S1142	E1136K	1136	Missense	distal	-6	no	4.575	4.624	EPSD	CCLE	4.322	Up-regulation
CAMK_CAMK2_CAMK2A_ST	P24588	AKAP5	Q9UQM7	CAMK2A	T87	L85P	85	Missense	proximal	-2	no	7.285	7.394	EPSD;PhosphoSitePlus	CCLE	4.810	Up-regulation
CAMK_CAMK2_CAMK2A_ST	P24588	AKAP5	Q9UQM7	CAMK2A	S92	L85P	85	Missense	distal	-7	no	7.739	7.773	PhosphoSitePlus;EPSD	CCLE	4.810	Up-regulation
CAMK_CAMK2_CAMK2A_ST	Q14524	SCN5A	Q9UQM7	CAMK2A	S330	G327R	327	Missense	distal	-3	no	0.938	5.536	EPSD	CCLE	4.810	Gain
CAMK_CAMK2_CAMK2A_ST	Q14524	SCN5A	Q9UQM7	CAMK2A	S571	P564S	564	Missense	distal	-7	no	6.593	6.464	EPSD;PhosphoSitePlus	CCLE	4.810	Down-regulation
CAMK_CAMK2_CAMK2A_ST	Q14524	SCN5A	Q9UQM7	CAMK2A	S1925	R1919H	1919	Missense	distal	-6	no	5.284	5.238	EPSD;PhosphoSitePlus	CCLE	4.810	Down-regulation
CAMK_CAMK2_CAMK2A_ST	P35367	HRH1	Q9UQM7	CAMK2A	T142	T140A	140	Missense	proximal	-2	no	6.650	6.801	PhosphoSitePlus;EPSD	CCLE	4.810	Up-regulation
CAMK_CAMK2_CAMK2A_ST	P35367	HRH1	Q9UQM7	CAMK2A	S363	T366I	366	Missense	distal	3	no	6.631	6.582	EPSD	CCLE	4.810	Down-regulation
CAMK_CAMK2_CAMK2A_ST	P15036	ETS2	Q9UQM7	CAMK2A	S310	F311L	311	Missense	proximal	1	no	6.673	6.779	PhosphoSitePlus;EPSD	CCLE	4.810	Up-regulation
CAMK_CAMK2_CAMK2A_ST	P15036	ETS2	Q9UQM7	CAMK2A	S313	F311L	311	Missense	proximal	-2	no	4.578	5.260	EPSD;PhosphoSitePlus	CCLE	4.810	Gain
CAMK_CAMK2_CAMK2A_ST	P23677	ITPKA	Q9UQM7	CAMK2A	S121	R118C	118	Missense	distal	-3	no	7.069	1.488	EPSD	CCLE	4.810	Loss
CAMK_CAMK2_CAMK2A_ST	P23677	ITPKA	Q9UQM7	CAMK2A	T122	R118C	118	Missense	distal	-4	no	8.134	7.500	EPSD	CCLE	4.810	Down-regulation
CAMK_CAMK2_CAMK2A_ST	Q9Y618	NCOR2	Q9UQM7	CAMK2A	S132	R139C	139	Missense	distal	7	no	4.822	4.977	EPSD	CCLE	4.810	Up-regulation
CAMK_CAMK2_CAMK2A_ST	Q9Y618	NCOR2	Q9UQM7	CAMK2A	S140	R139C	139	Missense	proximal	-1	no	5.987	5.658	EPSD	CCLE	4.810	Down-regulation
CAMK_CAMK2_CAMK2A_ST	Q9Y618	NCOR2	Q9UQM7	CAMK2A	S745	E749K	749	Missense	distal	4	no	5.729	5.553	EPSD	CCLE	4.810	Down-regulation
CAMK_CAMK2_CAMK2A_ST	Q9Y618	NCOR2	Q9UQM7	CAMK2A	S1017	G1016D	1016	Missense	proximal	-1	no	4.945	4.911	EPSD	CCLE	4.810	Down-regulation
CAMK_CAMK2_CAMK2A_ST	Q9Y618	NCOR2	Q9UQM7	CAMK2A	S1017	P1015S	1015	Missense	proximal	-2	no	4.945	4.938	EPSD	CCLE	4.810	Down-regulation
CAMK_CAMK2_CAMK2A_ST	Q9Y618	NCOR2	Q9UQM7	CAMK2A	S1023	P1026S	1026	Missense	distal	3	no	7.889	8.161	EPSD	CCLE	4.810	Up-regulation
CAMK_CAMK2_CAMK2A_ST	Q9Y618	NCOR2	Q9UQM7	CAMK2A	S1023	G1016D	1016	Missense	distal	-7	no	7.889	7.801	EPSD	CCLE	4.810	Down-regulation
CAMK_CAMK2_CAMK2A_ST	Q9Y618	NCOR2	Q9UQM7	CAMK2A	S1025	P1026S	1026	Missense	proximal	1	no	5.954	6.321	EPSD	CCLE	4.810	Up-regulation
CAMK_CAMK2_CAMK2A_ST	Q9Y618	NCOR2	Q9UQM7	CAMK2A	S1270	L1263P	1263	Missense	distal	-7	no	8.140	8.174	EPSD	CCLE	4.810	Up-regulation
CAMK_CAMK2_CAMK2A_ST	Q9Y618	NCOR2	Q9UQM7	CAMK2A	T1522	S1518L	1518	Missense	distal	-4	no	5.787	5.490	EPSD	CCLE	4.810	Down-regulation
CAMK_CAMK2_CAMK2A_ST	Q9Y618	NCOR2	Q9UQM7	CAMK2A	S1627	L1623M	1623	Missense	distal	-4	no	5.850	5.923	EPSD	CCLE	4.810	Up-regulation
CAMK_CAMK2_CAMK2A_ST	Q14654	KCNJ11	Q9UQM7	CAMK2A	T224	V220A	220	Missense	distal	-4	no	5.257	5.546	EPSD;PhosphoSitePlus	CCLE	4.810	Up-regulation
CAMK_CAMK2_CAMK2A_ST	Q14654	KCNJ11	Q9UQM7	CAMK2A	S372	A378P	378	Missense	distal	6	no	9.838	9.713	EPSD	CCLE	4.810	Down-regulation
CAMK_CAMK2_CAMK2A_ST	Q14654	KCNJ11	Q9UQM7	CAMK2A	S372	S372N	372	Missense	central	0	yes	9.838	0.000	EPSD	CCLE	4.810	Loss
CAMK_CAMK2_CAMK2A_ST	P05556	ITGB1	Q9UQM7	CAMK2A	T60	G57R	57	Missense	distal	-3	no	2.501	7.099	EPSD	CCLE	4.810	Gain
CAMK_CAMK2_CAMK2A_ST	P07101	TH	Q9UQM7	CAMK2A	S71	R68H	68	Missense	distal	-3	no	9.735	4.238	EPSD;PhosphoSitePlus	CCLE	4.810	Loss
CAMK_CAMK2_CAMK2A_ST	P07101	TH	Q9UQM7	CAMK2A	S71	R68C	68	Missense	distal	-3	no	9.735	4.155	EPSD;PhosphoSitePlus	CCLE	4.810	Loss
CAMK_CAMK2_CAMK2A_ST	Q9UQM7	CAMK2A	Q9UQM7	CAMK2A	S331	S331P	331	Missense	central	0	yes	6.517	0.000	EPSD	CCLE	4.810	Loss
CAMK_CAMK2_CAMK2A_ST	Q9UQM7	CAMK2A	Q9UQM7	CAMK2A	S333	S331P	331	Missense	proximal	-2	no	5.401	5.408	EPSD	CCLE	4.810	Up-regulation
CAMK_CAMK2_CAMK2A_ST	P28329	CHAT	Q9UQM7	CAMK2A	S473	A471V	471	Missense	proximal	-2	no	8.060	7.643	EPSD	CCLE	4.810	Down-regulation
CAMK_CAMK2_CAMK2A_ST	P28329	CHAT	Q9UQM7	CAMK2A	S473	P480F	480	Missense	distal	7	no	8.060	8.208	EPSD	CCLE	4.810	Up-regulation
CAMK_CAMK2_CAMK2A_ST	P28329	CHAT	Q9UQM7	CAMK2A	T574	A579T	579	Missense	distal	5	no	5.843	5.631	EPSD	CCLE	4.810	Down-regulation
CAMK_CAMK2_CAMK2A_ST	P28329	CHAT	Q9UQM7	CAMK2A	T574	A579D	579	Missense	distal	5	no	5.843	5.668	EPSD	CCLE	4.810	Down-regulation
CAMK_CAMK2_CAMK2A_ST	P14921	ETS1	Q9UQM7	CAMK2A	S254	I255V	255	Missense	proximal	1	no	6.034	5.826	EPSD	CCLE	4.810	Down-regulation
CAMK_CAMK2_CAMK2A_ST	P14921	ETS1	Q9UQM7	CAMK2A	S257	I255V	255	Missense	proximal	-2	no	5.093	4.850	EPSD;PhosphoSitePlus	CCLE	4.810	Down-regulation
CAMK_CAMK2_CAMK2A_ST	P14921	ETS1	Q9UQM7	CAMK2A	S273	S273Y	273	Missense	central	0	yes	6.520	0.000	EPSD	CCLE	4.810	Loss
CAMK_CAMK2_CAMK2A_ST	P14921	ETS1	Q9UQM7	CAMK2A	S282	S285R	285	Missense	distal	3	no	9.486	9.391	EPSD;PhosphoSitePlus	CCLE	4.810	Down-regulation
CAMK_CAMK2_CAMK2A_ST	P14921	ETS1	Q9UQM7	CAMK2A	S285	S285R	285	Missense	central	0	yes	6.022	0.000	PhosphoSitePlus;EPSD	CCLE	4.810	Loss
CAMK_CAMK2_CAMK2A_ST	P14921	ETS1	Q9UQM7	CAMK2A	S288	S285R	285	Missense	distal	-3	no	4.047	8.508	EPSD	CCLE	4.810	Gain
CAMK_CAMK2_CAMK2A_ST	O95997	PTTG1	Q9UQM7	CAMK2A	S87	P80L	80	Missense	distal	-7	no	6.383	6.349	EPSD;PhosphoSitePlus	CCLE	4.810	Down-regulation
CAMK_CAMK2_CAMK2A_ST	Q15796	SMAD2	Q9UQM7	CAMK2A	S110	R114H	114	Missense	distal	4	no	6.202	6.314	EPSD;PhosphoSitePlus	CCLE	4.810	Up-regulation
CAMK_CAMK2_CAMK2A_ST	Q15796	SMAD2	Q9UQM7	CAMK2A	S240	S233G	233	Missense	distal	-7	no	4.917	5.216	EPSD;PhosphoSitePlus	CCLE	4.810	Up-regulation
CAMK_CAMK2_CAMK2A_ST	Q15796	SMAD2	Q9UQM7	CAMK2A	S260	L254F	254	Missense	distal	-6	no	5.329	5.390	PhosphoSitePlus;EPSD	CCLE	4.810	Up-regulation
CAMK_CAMK2_CAMK2A_ST	P46527	CDKN1B	Q9UQM7	CAMK2A	S12	S12I	12	Missense	central	0	yes	4.883	0.000	EPSD	CCLE	4.810	Loss
CAMK_CAMK2_CAMK2A_ST	P11831	SRF	Q9UQM7	CAMK2A	T27	S21N	21	Missense	distal	-6	no	6.589	6.691	EPSD	CCLE	4.810	Up-regulation
CAMK_CAMK2_CAMK2A_ST	P11831	SRF	Q9UQM7	CAMK2A	S372	R373C	373	Missense	proximal	1	no	4.910	4.879	EPSD	CCLE	4.810	Down-regulation
CAMK_CAMK2_CAMK2A_ST	Q9NQC7	CYLD	Q9UQM7	CAMK2A	S352	N348S	348	Missense	distal	-4	no	6.913	7.075	EPSD	CCLE	4.810	Up-regulation
CAMK_CAMK2_CAMK2A_ST	Q92736	RYR2	Q9UQM7	CAMK2A	S2031	L2029Q	2029	Missense	proximal	-2	no	6.199	6.591	EPSD	CCLE	4.810	Up-regulation
CAMK_CAMK2_CAMK2A_ST	Q9UQL6	HDAC5	Q9UQM7	CAMK2A	S16	G9R	9	Missense	distal	-7	no	10.215	9.884	EPSD	CCLE	4.810	Down-regulation
CAMK_CAMK2_CAMK2A_ST	Q9UQL6	HDAC5	Q9UQM7	CAMK2A	T479	T479I	479	Missense	central	0	yes	5.615	0.000	EPSD	CCLE	4.810	Loss
CAMK_CAMK2_CAMK2A_ST	Q9UQL6	HDAC5	Q9UQM7	CAMK2A	S713	R710G	710	Missense	distal	-3	no	6.895	2.297	EPSD	CCLE	4.810	Loss
CAMK_CAMK2_CAMK2A_ST	Q9UQL6	HDAC5	Q9UQM7	CAMK2A	S1108	E1113Q	1113	Missense	distal	5	no	9.007	8.927	EPSD	CCLE	4.810	Down-regulation
CAMK_CAMK2_CAMK2A_ST	Q9UQL6	HDAC5	Q9UQM7	CAMK2A	S1108	S1108G	1108	Missense	central	0	yes	9.007	0.000	EPSD	CCLE	4.810	Loss
CAMK_CAMK2_CAMK2A_ST	P08670	VIM	Q9UQM7	CAMK2A	S7	S8P	8	Missense	proximal	1	no	6.604	6.237	EPSD	CCLE	4.810	Down-regulation
CAMK_CAMK2_CAMK2A_ST	P08670	VIM	Q9UQM7	CAMK2A	S39	Y38H	38	Missense	proximal	-1	no	8.979	9.174	EPSD	CCLE	4.810	Up-regulation
CAMK_CAMK2_CAMK2A_ST	P08670	VIM	Q9UQM7	CAMK2A	S72	G76E	76	Missense	distal	4	no	7.061	7.288	EPSD	CCLE	4.810	Up-regulation
CAMK_CAMK2_CAMK2A_ST	P08670	VIM	Q9UQM7	CAMK2A	S83	G76E	76	Missense	distal	-7	no	6.036	5.747	PhosphoSitePlus	CCLE	4.810	Down-regulation
CAMK_CAMK2_CAMK2A_ST	P21333	FLNA	Q9UQM7	CAMK2A	S440	R443S	443	Missense	distal	3	no	4.755	4.849	EPSD	CCLE	4.810	Gain
CAMK_CAMK2_CAMK2A_ST	P21333	FLNA	Q9UQM7	CAMK2A	S630	P637L	637	Missense	distal	7	no	6.038	6.103	EPSD	CCLE	4.810	Up-regulation
CAMK_CAMK2_CAMK2A_ST	P21333	FLNA	Q9UQM7	CAMK2A	S630	G629S	629	Missense	proximal	-1	no	6.038	6.184	EPSD	CCLE	4.810	Up-regulation
CAMK_CAMK2_CAMK2A_ST	P21333	FLNA	Q9UQM7	CAMK2A	S748	W749F	749	Missense	proximal	1	no	4.247	4.909	EPSD	CCLE	4.810	Gain
CAMK_CAMK2_CAMK2A_ST	P21333	FLNA	Q9UQM7	CAMK2A	S1081	Q1078R	1078	Missense	distal	-3	no	4.249	7.821	EPSD	CCLE	4.810	Gain
CAMK_CAMK2_CAMK2A_ST	O43526	KCNQ2	Q9UQM7	CAMK2A	S503	A510T	510	Missense	distal	7	no	4.957	5.005	EPSD	CCLE	4.810	Up-regulation
CAMK_CAMK2_CAMK2A_ST	O43526	KCNQ2	Q9UQM7	CAMK2A	S507	A510T	510	Missense	distal	3	no	10.358	10.123	EPSD	CCLE	4.810	Down-regulation
CAMK_CAMK2_CAMK2A_ST	Q06210	GFPT1	Q9UQM7	CAMK2A	T98	S103N	103	Missense	distal	5	no	6.186	6.073	EPSD	CCLE	4.810	Down-regulation
CAMK_CAMK2_CAMK2A_ST	Q06210	GFPT1	Q9UQM7	CAMK2A	T98	T94S	94	Missense	distal	-4	no	6.186	6.467	EPSD	CCLE	4.810	Up-regulation
CAMK_CAMK2_CAMK2A_ST	O14490	DLGAP1	Q9UQM7	CAMK2A	S375	R372W	372	Missense	distal	-3	no	7.065	-4.956	EPSD	CCLE	4.810	Loss
CAMK_CAMK2_CAMK2A_ST	O14490	DLGAP1	Q9UQM7	CAMK2A	S440	M442R	442	Missense	proximal	2	no	6.888	7.215	EPSD	CCLE	4.810	Up-regulation
CAMK_CAMK2_CAMK2A_ST	O14490	DLGAP1	Q9UQM7	CAMK2A	S515	T522A	522	Missense	distal	7	no	7.871	7.822	EPSD	CCLE	4.810	Down-regulation
CAMK_CAMK2_CAMK2A_ST	O14490	DLGAP1	Q9UQM7	CAMK2A	S932	S935T	935	Missense	distal	3	no	10.921	10.725	EPSD	CCLE	4.810	Down-regulation
CAMK_CAMK2_CAMK2A_ST	O14490	DLGAP1	Q9UQM7	CAMK2A	S958	N957T	957	Missense	proximal	-1	no	8.147	8.122	EPSD	CCLE	4.810	Down-regulation
CAMK_CAMK2_CAMK2A_ST	O14490	DLGAP1	Q9UQM7	CAMK2A	S958	N957Y	957	Missense	proximal	-1	no	8.147	8.145	EPSD	CCLE	4.810	Down-regulation
CAMK_CAMK2_CAMK2A_ST	O14490	DLGAP1	Q9UQM7	CAMK2A	S962	E967Q	967	Missense	distal	5	no	6.538	6.458	EPSD	CCLE	4.810	Down-regulation
CAMK_CAMK2_CAMK2A_ST	O14490	DLGAP1	Q9UQM7	CAMK2A	S962	N957T	957	Missense	distal	-5	no	6.538	6.472	EPSD	CCLE	4.810	Down-regulation
CAMK_CAMK2_CAMK2A_ST	O14490	DLGAP1	Q9UQM7	CAMK2A	S962	N957Y	957	Missense	distal	-5	no	6.538	6.483	EPSD	CCLE	4.810	Down-regulation
CAMK_CAMK2_CAMK2A_ST	P55055	NR1H2	Q9UQM7	CAMK2A	S426	M420I	420	Missense	distal	-6	no	6.813	6.870	PhosphoSitePlus	CCLE	4.810	Up-regulation
CAMK_CAMK2_CAMK2A_ST	P51790	CLCN3	Q9UQM7	CAMK2A	S109	R105T	105	Missense	distal	-4	no	8.332	8.119	PhosphoSitePlus	CCLE	4.810	Down-regulation
CAMK_CAMK2_CAMK2A_ST	P40189	IL6ST	Q9UQM7	CAMK2A	S820	Q817R	817	Missense	distal	-3	no	3.220	6.791	EPSD	CCLE	4.810	Gain
CAMK_CAMK2_CAMK2A_ST	Q00613	HSF1	Q9UQM7	CAMK2A	S283	R287M	287	Missense	distal	4	no	6.199	6.244	EPSD	CCLE	4.810	Up-regulation
CAMK_CAMK2_CAMK2A_ST	Q00613	HSF1	Q9UQM7	CAMK2A	S290	R287M	287	Missense	distal	-3	no	6.695	1.877	EPSD	CCLE	4.810	Loss
CAMK_CAMK2_CAMK2A_ST	Q4G163	FBXO43	Q9UQM7	CAMK2A	S344	L341M	341	Missense	distal	-3	no	4.549	4.853	EPSD	CCLE	4.810	Gain
CAMK_CAMK2_CAMK2A_ST	P55042	RRAD	Q9UQM7	CAMK2A	S26	P28T	28	Missense	proximal	2	no	6.328	6.179	EPSD	CCLE	4.810	Down-regulation
CAMK_CAMK2_CAMK2A_ST	P55042	RRAD	Q9UQM7	CAMK2A	S214	E212K	212	Missense	proximal	-2	no	11.533	11.757	EPSD	CCLE	4.810	Up-regulation
CAMK_CAMK2_CAMK2A_ST	P35372	OPRM1	Q9UQM7	CAMK2A	S263	S270C	270	Missense	distal	7	no	6.592	6.852	EPSD	CCLE	4.810	Up-regulation
CAMK_CAMK2_CAMK2A_ST	P35372	OPRM1	Q9UQM7	CAMK2A	S268	S270C	270	Missense	proximal	2	no	6.827	6.806	PhosphoSitePlus	CCLE	4.810	Down-regulation
CAMK_CAMK2_CAMK2A_ST	Q9Y496	KIF3A	Q9UQM7	CAMK2A	S217	S218F	218	Missense	proximal	1	no	4.684	4.870	EPSD	CCLE	4.810	Gain
CAMK_CAMK2_CAMK2A_ST	Q9Y4D2	DAGLA	Q9UQM7	CAMK2A	S929	D924E	924	Missense	distal	-5	no	6.348	6.184	EPSD	CCLE	4.810	Down-regulation
CAMK_CAMK2_CAMK2A_ST	Q9Y4D2	DAGLA	Q9UQM7	CAMK2A	S954	E957K	957	Missense	distal	3	no	4.938	4.773	EPSD	CCLE	4.810	Loss
CAMK_CAMK2_CAMK2A_ST	Q01970	PLCB3	Q9UQM7	CAMK2A	S26	I29V	29	Missense	distal	3	no	6.880	7.103	EPSD	CCLE	4.810	Up-regulation
CAMK_CAMK2_CAMK2A_ST	Q01970	PLCB3	Q9UQM7	CAMK2A	S512	S505F	505	Missense	distal	-7	no	5.940	6.501	EPSD	CCLE	4.810	Up-regulation
CAMK_CAMK2_CAMK2A_ST	Q01970	PLCB3	Q9UQM7	CAMK2A	S814	H808R	808	Missense	distal	-6	no	4.771	4.817	EPSD	CCLE	4.810	Gain
CAMK_CAMK2_CAMK2A_ST	Q14674	ESPL1	Q9UQM7	CAMK2A	S1433	S1433N	1433	Missense	central	0	yes	5.412	0.000	EPSD	CCLE	4.810	Loss
CAMK_CAMK2_CAMK2A_ST	Q14674	ESPL1	Q9UQM7	CAMK2A	S1501	L1505P	1505	Missense	distal	4	no	9.499	9.536	PhosphoSitePlus	CCLE	4.810	Up-regulation
CAMK_CAMK2_CAMK2A_ST	O95180	CACNA1H	Q9UQM7	CAMK2A	S475	R477H	477	Missense	proximal	2	no	5.128	4.060	EPSD	CCLE	4.810	Loss
CAMK_CAMK2_CAMK2A_ST	O95180	CACNA1H	Q9UQM7	CAMK2A	S484	R477H	477	Missense	distal	-7	no	5.694	5.635	EPSD	CCLE	4.810	Down-regulation
CAMK_CAMK2_CAMK2A_ST	O95180	CACNA1H	Q9UQM7	CAMK2A	S484	R485C	485	Missense	proximal	1	no	5.694	5.664	EPSD	CCLE	4.810	Down-regulation
CAMK_CAMK2_CAMK2A_ST	O95180	CACNA1H	Q9UQM7	CAMK2A	T1175	E1170K	1170	Missense	distal	-5	no	5.004	5.001	EPSD	CCLE	4.810	Down-regulation
CAMK_CAMK2_CAMK2A_ST	O95180	CACNA1H	Q9UQM7	CAMK2A	S1198	P1203T	1203	Missense	distal	5	no	9.663	9.732	PhosphoSitePlus	CCLE	4.810	Up-regulation
CAMK_CAMK2_CAMK2A_ST	O95180	CACNA1H	Q9UQM7	CAMK2A	S1587	R1586M	1586	Missense	proximal	-1	no	5.655	5.736	EPSD	CCLE	4.810	Up-regulation
CAMK_CAMK2_CAMK2A_ST	O95180	CACNA1H	Q9UQM7	CAMK2A	S1926	Y1932H	1932	Missense	distal	6	no	8.009	8.093	EPSD	CCLE	4.810	Up-regulation
CAMK_CAMK2_CAMK2A_ST	P78352	DLG4	Q9UQM7	CAMK2A	S453	V459A	459	Missense	distal	6	no	5.039	5.203	EPSD	CCLE	4.810	Up-regulation
CAMK_CAMK2_CAMK2A_ST	P78352	DLG4	Q9UQM7	CAMK2A	S478	R475Q	475	Missense	distal	-3	no	7.225	3.654	EPSD	CCLE	4.810	Loss
CAMK_CAMK2_CAMK2A_ST	P78352	DLG4	Q9UQM7	CAMK2A	S654	A647T	647	Missense	distal	-7	no	8.254	8.595	EPSD	CCLE	4.810	Up-regulation
CAMK_CAMK2_CAMK2A_ST	Q14457	BECN1	Q9UQM7	CAMK2A	S90	S93N	93	Missense	distal	3	no	9.575	9.461	PhosphoSitePlus	CCLE	4.810	Down-regulation
CAMK_CAMK2_CAMK2A_ST	Q13224	GRIN2B	Q9UQM7	CAMK2A	S1166	S1159G	1159	Missense	distal	-7	no	5.799	6.098	EPSD	CCLE	4.810	Up-regulation
CAMK_CAMK2_CAMK2A_ST	P10636	MAPT	Q9UQM7	CAMK2A	S113	G107V	107	Missense	distal	-6	no	4.846	4.793	EPSD	CCLE	4.810	Loss
CAMK_CAMK2_CAMK2A_ST	P10636	MAPT	Q9UQM7	CAMK2A	T167	E161Q	161	Missense	distal	-6	no	5.827	5.903	EPSD	CCLE	4.810	Up-regulation
CAMK_CAMK2_CAMK2A_ST	P10636	MAPT	Q9UQM7	CAMK2A	T167	P170F	170	Missense	distal	3	no	5.827	5.721	EPSD	CCLE	4.810	Down-regulation
CAMK_CAMK2_CAMK2A_ST	P10636	MAPT	Q9UQM7	CAMK2A	T167	G174A	174	Missense	distal	7	no	5.827	5.778	EPSD	CCLE	4.810	Down-regulation
CAMK_CAMK2_CAMK2A_ST	P10636	MAPT	Q9UQM7	CAMK2A	S171	P170F	170	Missense	proximal	-1	no	5.997	5.841	EPSD	CCLE	4.810	Down-regulation
CAMK_CAMK2_CAMK2A_ST	P10636	MAPT	Q9UQM7	CAMK2A	S171	G174A	174	Missense	distal	3	no	5.997	6.187	EPSD	CCLE	4.810	Up-regulation
CAMK_CAMK2_CAMK2A_ST	P10636	MAPT	Q9UQM7	CAMK2A	S214	D221Y	221	Missense	distal	7	no	8.732	8.841	EPSD	CCLE	4.810	Up-regulation
CAMK_CAMK2_CAMK2A_ST	P10636	MAPT	Q9UQM7	CAMK2A	T403	K405R	405	Missense	proximal	2	no	3.853	5.395	EPSD	CCLE	4.810	Gain
CAMK_CAMK2_CAMK2A_ST	P10636	MAPT	Q9UQM7	CAMK2A	T529	R526L	526	Missense	distal	-3	no	6.612	1.489	EPSD	CCLE	4.810	Loss
CAMK_CAMK2_CAMK2A_ST	P10636	MAPT	Q9UQM7	CAMK2A	S531	R526L	526	Missense	distal	-5	no	6.480	6.460	EPSD	CCLE	4.810	Down-regulation
CAMK_CAMK2_CAMK2A_ST	P10636	MAPT	Q9UQM7	CAMK2A	S554	R559H	559	Missense	distal	5	no	5.018	5.132	EPSD	CCLE	4.810	Up-regulation
CAMK_CAMK2_CAMK2A_ST	P10636	MAPT	Q9UQM7	CAMK2A	T562	R559H	559	Missense	distal	-3	no	5.947	0.450	EPSD	CCLE	4.810	Loss
CAMK_CAMK2_CAMK2A_ST	P10636	MAPT	Q9UQM7	CAMK2A	S579	K574N	574	Missense	distal	-5	no	6.153	6.332	EPSD	CCLE	4.810	Up-regulation
CAMK_CAMK2_CAMK2A_ST	P10636	MAPT	Q9UQM7	CAMK2A	S726	S721C	721	Missense	distal	-5	no	6.647	6.574	EPSD	CCLE	4.810	Down-regulation
CAMK_CAMK2_CAMK2A_ST	P10636	MAPT	Q9UQM7	CAMK2A	S726	H724R	724	Missense	proximal	-2	no	6.647	6.767	EPSD	CCLE	4.810	Up-regulation
CAMK_CAMK2_CAMK2A_ST	P10636	MAPT	Q9UQM7	CAMK2A	T744	Q741K	741	Missense	distal	-3	no	4.520	5.823	EPSD	CCLE	4.810	Gain
Other_Aur_AURKA_ST	Q14194	CRMP1	O14965	AURKA	T101	D106H	106	Missense	distal	5	no	43.523	41.945	PhosphoSitePlus;EPSD	CCLE	39.062	Down-regulation
Other_Aur_AURKA_ST	Q14194	CRMP1	O14965	AURKA	T102	D106H	106	Missense	distal	4	no	50.086	50.017	EPSD;PhosphoSitePlus	CCLE	39.062	Down-regulation
Other_Aur_AURKA_ST	O43379	WDR62	O14965	AURKA	S1435	V1439A	1439	Missense	distal	4	no	41.817	42.110	EPSD	CCLE	39.062	Up-regulation
Other_Aur_AURKA_ST	Q9UNN5	FAF1	O14965	AURKA	S212	R205W	205	Missense	distal	-7	no	43.863	40.563	EPSD	CCLE	39.062	Down-regulation
Other_Aur_AURKA_ST	Q9UNN5	FAF1	O14965	AURKA	T264	P259L	259	Missense	distal	-5	no	42.901	42.913	EPSD	CCLE	39.062	Up-regulation
Other_Aur_AURKA_ST	Q9UNN5	FAF1	O14965	AURKA	S320	A316T	316	Missense	distal	-4	no	36.193	41.151	EPSD	CCLE	39.062	Gain
Other_Aur_AURKA_ST	Q14980	NUMA1	O14965	AURKA	S271	A269P	269	Missense	proximal	-2	no	41.767	38.346	EPSD	CCLE	39.062	Loss
Other_Aur_AURKA_ST	Q14980	NUMA1	O14965	AURKA	S1830	S1837N	1837	Missense	distal	7	no	41.852	41.773	EPSD	CCLE	39.062	Down-regulation
Other_Aur_AURKA_ST	Q14980	NUMA1	O14965	AURKA	S1847	Q1845H	1845	Missense	proximal	-2	no	38.139	41.540	EPSD	CCLE	39.062	Gain
Other_Aur_AURKA_ST	Q14980	NUMA1	O14965	AURKA	S1847	A1843T	1843	Missense	distal	-4	no	38.139	43.097	EPSD	CCLE	39.062	Gain
Other_Aur_AURKA_ST	Q14980	NUMA1	O14965	AURKA	T1851	Q1845H	1845	Missense	distal	-6	no	41.206	39.904	EPSD	CCLE	39.062	Down-regulation
Other_Aur_AURKA_ST	Q14980	NUMA1	O14965	AURKA	T1879	T1879A	1879	Missense	central	0	yes	45.315	0.000	EPSD	CCLE	39.062	Loss
Other_Aur_AURKA_ST	Q14980	NUMA1	O14965	AURKA	S1883	T1879A	1879	Missense	distal	-4	no	42.852	37.893	EPSD	CCLE	39.062	Loss
Other_Aur_AURKA_ST	Q14980	NUMA1	O14965	AURKA	S1942	C1937Y	1937	Missense	distal	-5	no	40.777	40.661	EPSD	CCLE	39.062	Down-regulation
Other_Aur_AURKA_ST	Q96EZ8	MCRS1	O14965	AURKA	S35	Q31E	31	Missense	distal	-4	no	45.580	46.944	EPSD;PhosphoSitePlus	CCLE	39.062	Up-regulation
Other_Aur_AURKA_ST	Q96EZ8	MCRS1	O14965	AURKA	S36	Q31E	31	Missense	distal	-5	no	46.092	46.096	PhosphoSitePlus;EPSD	CCLE	39.062	Up-regulation
Other_Aur_AURKA_ST	Q96R06	SPAG5	O14965	AURKA	S334	L332V	332	Missense	proximal	-2	no	39.101	37.782	EPSD	CCLE	39.062	Loss
Other_Aur_AURKA_ST	Q14203	DCTN1	O14965	AURKA	T145	A142T	142	Missense	distal	-3	no	39.286	37.562	EPSD	CCLE	39.062	Loss
Other_Aur_AURKA_ST	Q14203	DCTN1	O14965	AURKA	T146	A142T	142	Missense	distal	-4	no	57.314	62.272	EPSD	CCLE	39.062	Up-regulation
Other_Aur_AURKA_ST	Q14203	DCTN1	O14965	AURKA	S203	P199L	199	Missense	distal	-4	no	44.393	45.544	EPSD	CCLE	39.062	Up-regulation
Other_Aur_AURKA_ST	Q14203	DCTN1	O14965	AURKA	S974	V971M	971	Missense	distal	-3	no	45.307	37.571	EPSD	CCLE	39.062	Loss
Other_Aur_AURKA_ST	Q13761	RUNX3	O14965	AURKA	S71	T69P	69	Missense	proximal	-2	no	37.066	41.220	EPSD	CCLE	39.062	Gain
Other_Aur_AURKA_ST	Q13761	RUNX3	O14965	AURKA	T209	L204P	204	Missense	distal	-5	no	47.344	47.331	EPSD	CCLE	39.062	Down-regulation
Other_Aur_AURKA_ST	Q13761	RUNX3	O14965	AURKA	S218	T221P	221	Missense	distal	3	no	46.876	48.811	EPSD	CCLE	39.062	Up-regulation
Other_Aur_AURKA_ST	Q13761	RUNX3	O14965	AURKA	S220	T221P	221	Missense	proximal	1	no	52.679	50.431	EPSD	CCLE	39.062	Down-regulation
Other_Aur_AURKA_ST	Q13761	RUNX3	O14965	AURKA	S226	T221P	221	Missense	distal	-5	no	42.102	42.073	EPSD	CCLE	39.062	Down-regulation
Other_Aur_AURKA_ST	P46937	YAP1	O14965	AURKA	S274	I273T	273	Missense	proximal	-1	no	51.592	51.801	EPSD	CCLE	39.062	Up-regulation
Other_Aur_AURKA_ST	P46937	YAP1	O14965	AURKA	S419	D421N	421	Missense	proximal	2	no	40.480	38.689	EPSD	CCLE	39.062	Loss
Other_Aur_AURKA_ST	Q92974	ARHGEF2	O14965	AURKA	S142	A147T	147	Missense	distal	5	no	47.482	48.113	EPSD	CCLE	39.062	Up-regulation
Other_Aur_AURKA_ST	Q92974	ARHGEF2	O14965	AURKA	S143	A147T	147	Missense	distal	4	no	47.935	46.887	EPSD	CCLE	39.062	Down-regulation
Other_Aur_AURKA_ST	Q92974	ARHGEF2	O14965	AURKA	S186	E193Q	193	Missense	distal	7	no	42.760	42.636	EPSD	CCLE	39.062	Down-regulation
Other_Aur_AURKA_ST	Q92974	ARHGEF2	O14965	AURKA	S696	G692S	692	Missense	distal	-4	no	43.927	45.047	EPSD	CCLE	39.062	Up-regulation
Other_Aur_AURKA_ST	P38398	BRCA1	O14965	AURKA	S308	R315M	315	Missense	distal	7	no	41.070	41.047	PhosphoSitePlus	CCLE	39.062	Down-regulation
Other_Aur_AURKA_ST	P38398	BRCA1	O14965	AURKA	S378	T374I	374	Missense	distal	-4	no	41.436	33.729	EPSD	CCLE	39.062	Loss
Other_Aur_AURKA_ST	P38398	BRCA1	O14965	AURKA	S398	E404D	404	Missense	distal	6	no	41.810	42.020	EPSD	CCLE	39.062	Up-regulation
Other_Aur_AURKA_ST	P38398	BRCA1	O14965	AURKA	S844	E851G	851	Missense	distal	7	no	41.686	41.757	EPSD	CCLE	39.062	Up-regulation
Other_Aur_AURKA_ST	P38398	BRCA1	O14965	AURKA	T967	L973F	973	Missense	distal	6	no	38.929	39.138	EPSD	CCLE	39.062	Gain
Other_Aur_AURKA_ST	P38398	BRCA1	O14965	AURKA	S1286	K1290T	1290	Missense	distal	4	no	41.144	39.684	EPSD	CCLE	39.062	Down-regulation
Other_Aur_AURKA_ST	P38398	BRCA1	O14965	AURKA	S1328	M1324V	1324	Missense	distal	-4	no	38.064	39.601	EPSD	CCLE	39.062	Gain
Other_Aur_AURKA_ST	P38398	BRCA1	O14965	AURKA	S1610	E1609D	1609	Missense	proximal	-1	no	42.672	44.772	EPSD	CCLE	39.062	Up-regulation
Other_Aur_AURKA_ST	P12755	SKI	O14965	AURKA	S325	I332T	332	Missense	distal	7	no	51.752	51.577	EPSD	CCLE	39.062	Down-regulation
Other_Aur_AURKA_ST	P12755	SKI	O14965	AURKA	S326	I332T	332	Missense	distal	6	no	47.043	46.874	EPSD;PhosphoSitePlus	CCLE	39.062	Down-regulation
Other_Aur_AURKA_ST	P12755	SKI	O14965	AURKA	S366	G361S	361	Missense	distal	-5	no	42.403	42.419	EPSD	CCLE	39.062	Up-regulation
Other_Aur_AURKA_ST	P12755	SKI	O14965	AURKA	S498	S501F	501	Missense	distal	3	no	41.320	41.374	EPSD	CCLE	39.062	Up-regulation
Other_Aur_AURKA_ST	P12755	SKI	O14965	AURKA	S498	T505I	505	Missense	distal	7	no	41.320	41.495	EPSD	CCLE	39.062	Up-regulation
Other_Aur_AURKA_ST	P12755	SKI	O14965	AURKA	S501	S501F	501	Missense	central	0	yes	40.310	0.000	EPSD	CCLE	39.062	Loss
Other_Aur_AURKA_ST	P12755	SKI	O14965	AURKA	S501	T505I	505	Missense	distal	4	no	40.310	41.912	EPSD	CCLE	39.062	Up-regulation
Other_Aur_AURKA_ST	P12755	SKI	O14965	AURKA	S509	T505I	505	Missense	distal	-4	no	41.921	34.214	EPSD	CCLE	39.062	Loss
Other_Aur_AURKA_ST	Q9BQG0	MYBBP1A	O14965	AURKA	S672	C678Y	678	Missense	distal	6	no	46.627	46.746	EPSD	CCLE	39.062	Up-regulation
Other_Aur_AURKA_ST	Q9BQG0	MYBBP1A	O14965	AURKA	S864	S859G	859	Missense	distal	-5	no	41.301	41.286	EPSD	CCLE	39.062	Down-regulation
Other_Aur_AURKA_ST	Q9BQG0	MYBBP1A	O14965	AURKA	S864	R858H	858	Missense	distal	-6	no	41.301	39.132	EPSD	CCLE	39.062	Down-regulation
Other_Aur_AURKA_ST	P40337	VHL	O14965	AURKA	S72	E70D	70	Missense	proximal	-2	no	46.918	58.902	PhosphoSitePlus	CCLE	39.062	Up-regulation
Other_Aur_AURKA_ST	P40337	VHL	O14965	AURKA	S168	E173D	173	Missense	distal	5	no	46.126	47.054	EPSD	CCLE	39.062	Up-regulation
Other_Aur_AURKA_ST	P53671	LIMK2	O14965	AURKA	S166	R163W	163	Missense	distal	-3	no	45.000	-34.172	EPSD	CCLE	39.062	Loss
Other_Aur_AURKA_ST	P53671	LIMK2	O14965	AURKA	S319	S318F	318	Missense	proximal	-1	no	39.346	40.419	EPSD	CCLE	39.062	Up-regulation
Other_Aur_AURKA_ST	P53671	LIMK2	O14965	AURKA	S319	Q324K	324	Missense	distal	5	no	39.346	38.653	EPSD	CCLE	39.062	Loss
Other_Aur_AURKA_ST	P53671	LIMK2	O14965	AURKA	S322	S318F	318	Missense	distal	-4	no	41.378	37.329	EPSD	CCLE	39.062	Loss
Other_Aur_AURKA_ST	P53671	LIMK2	O14965	AURKA	S322	Q324K	324	Missense	proximal	2	no	41.378	37.973	EPSD	CCLE	39.062	Loss
Other_Aur_AURKA_ST	P53671	LIMK2	O14965	AURKA	T505	N509S	509	Missense	distal	4	no	45.859	46.734	EPSD;PhosphoSitePlus	CCLE	39.062	Up-regulation
Other_Aur_AURKA_ST	Q8TEW0	PARD3	O14965	AURKA	S383	S380N	380	Missense	distal	-3	no	42.101	42.745	EPSD	CCLE	39.062	Up-regulation
Other_Aur_AURKA_ST	Q8TEW0	PARD3	O14965	AURKA	S485	G484D	484	Missense	proximal	-1	no	41.134	42.397	EPSD	CCLE	39.062	Up-regulation
Other_Aur_AURKA_ST	Q8TEW0	PARD3	O14965	AURKA	S533	K535N	535	Missense	proximal	2	no	40.374	42.418	EPSD	CCLE	39.062	Up-regulation
Other_Aur_AURKA_ST	Q8TEW0	PARD3	O14965	AURKA	S873	K870R	870	Missense	distal	-3	no	36.357	44.183	EPSD	CCLE	39.062	Gain
Other_Aur_AURKA_ST	Q8TEW0	PARD3	O14965	AURKA	S1196	E1200V	1200	Missense	distal	4	no	52.969	52.249	EPSD	CCLE	39.062	Down-regulation
Other_Aur_AURKA_ST	Q8TEW0	PARD3	O14965	AURKA	S1222	Q1215H	1215	Missense	distal	-7	no	42.703	41.750	EPSD	CCLE	39.062	Down-regulation
Other_Aur_AURKA_ST	Q8NHV4	NEDD1	O14965	AURKA	S89	S87C	87	Missense	proximal	-2	no	40.660	38.521	EPSD	CCLE	39.062	Loss
Other_Aur_AURKA_ST	Q8NHV4	NEDD1	O14965	AURKA	S215	E219D	219	Missense	distal	4	no	39.454	39.202	EPSD	CCLE	39.062	Down-regulation
Other_Aur_AURKA_ST	Q8NHV4	NEDD1	O14965	AURKA	S405	G407S	407	Missense	proximal	2	no	46.873	46.707	PhosphoSitePlus	CCLE	39.062	Down-regulation
Other_Aur_AURKA_ST	Q8NHV4	NEDD1	O14965	AURKA	S405	S411L	411	Missense	distal	6	no	46.873	46.809	PhosphoSitePlus	CCLE	39.062	Down-regulation
Other_Aur_AURKA_ST	Q8NHV4	NEDD1	O14965	AURKA	T480	R477H	477	Missense	distal	-3	no	41.078	35.305	EPSD	CCLE	39.062	Loss
Other_Aur_AURKA_ST	P53350	PLK1	O14965	AURKA	S326	F325V	325	Missense	proximal	-1	no	44.780	42.549	EPSD	CCLE	39.062	Down-regulation
Other_Aur_AURKA_ST	P53350	PLK1	O14965	AURKA	T366	G367A	367	Missense	proximal	1	no	37.157	39.677	EPSD	CCLE	39.062	Gain
Other_Aur_AURKA_ST	P03372	ESR1	O14965	AURKA	S236	A239D	239	Missense	distal	3	no	39.350	41.559	EPSD	CCLE	39.062	Up-regulation
Other_Aur_AURKA_ST	P06748	NPM1	O14965	AURKA	S137	K141R	141	Missense	distal	4	no	39.719	38.744	EPSD	CCLE	39.062	Loss
Other_Aur_AURKA_ST	P06748	NPM1	O14965	AURKA	S143	K141R	141	Missense	proximal	-2	no	49.237	55.741	EPSD	CCLE	39.062	Up-regulation
Other_Aur_AURKA_ST	Q9NRM7	LATS2	O14965	AURKA	S288	G293D	293	Missense	distal	5	no	38.898	39.732	EPSD	CCLE	39.062	Gain
Other_Aur_AURKA_ST	Q9NRM7	LATS2	O14965	AURKA	S380	K383R	383	Missense	distal	3	no	70.275	70.895	EPSD;PhosphoSitePlus	CCLE	39.062	Up-regulation
Other_Aur_AURKA_ST	O15350	TP73	O14965	AURKA	S223	R216H	216	Missense	distal	-7	no	40.317	38.842	EPSD	CCLE	39.062	Loss
Other_Aur_AURKA_ST	O15350	TP73	O14965	AURKA	S471	S477L	477	Missense	distal	6	no	40.632	40.568	EPSD	CCLE	39.062	Down-regulation
Other_Aur_AURKA_ST	O95983	MBD3	O14965	AURKA	S39	G40R	40	Missense	proximal	1	no	38.461	39.281	EPSD	CCLE	39.062	Gain
Other_Aur_AURKA_ST	O95983	MBD3	O14965	AURKA	S56	R51C	51	Missense	distal	-5	no	48.982	49.105	EPSD	CCLE	39.062	Up-regulation
Other_Aur_AURKA_ST	O95983	MBD3	O14965	AURKA	S77	K76N	76	Missense	proximal	-1	no	39.538	38.057	EPSD	CCLE	39.062	Loss
Other_Aur_AURKA_ST	Q99708	RBBP8	O14965	AURKA	T241	A236S	236	Missense	distal	-5	no	39.537	39.566	EPSD	CCLE	39.062	Up-regulation
Other_Aur_AURKA_ST	Q99708	RBBP8	O14965	AURKA	S242	A236S	236	Missense	distal	-6	no	42.709	42.493	EPSD	CCLE	39.062	Down-regulation
Other_Aur_AURKA_ST	Q99708	RBBP8	O14965	AURKA	S327	V325L	325	Missense	proximal	-2	no	46.400	47.719	EPSD;PhosphoSitePlus	CCLE	39.062	Up-regulation
Other_Aur_AURKA_ST	Q99708	RBBP8	O14965	AURKA	S649	N652I	652	Missense	distal	3	no	35.313	39.475	EPSD	CCLE	39.062	Gain
Other_Aur_AURKA_ST	Q96EB6	SIRT1	O14965	AURKA	S659	E662D	662	Missense	distal	3	no	40.032	41.077	EPSD	CCLE	39.062	Up-regulation
Other_Aur_AURKA_ST	Q14511	NEDD9	O14965	AURKA	S202	A196T	196	Missense	distal	-6	no	42.491	42.270	EPSD	CCLE	39.062	Down-regulation
Other_Aur_AURKA_ST	Q9ULW0	TPX2	O14965	AURKA	S121	R120K	120	Missense	proximal	-1	no	46.346	45.998	PhosphoSitePlus;EPSD	CCLE	39.062	Down-regulation
Other_Aur_AURKA_ST	Q9ULW0	TPX2	O14965	AURKA	S121	S121C	121	Missense	central	0	yes	46.346	0.000	PhosphoSitePlus;EPSD	CCLE	39.062	Loss
Other_Aur_AURKA_ST	Q9ULW0	TPX2	O14965	AURKA	S125	R120K	120	Missense	distal	-5	no	55.518	55.493	EPSD;PhosphoSitePlus	CCLE	39.062	Down-regulation
Other_Aur_AURKA_ST	Q9ULW0	TPX2	O14965	AURKA	S125	S121C	121	Missense	distal	-4	no	55.518	51.516	EPSD;PhosphoSitePlus	CCLE	39.062	Down-regulation
Other_Aur_AURKA_ST	Q9ULW0	TPX2	O14965	AURKA	T499	R496G	496	Missense	distal	-3	no	40.933	35.739	EPSD	CCLE	39.062	Loss
Other_Aur_AURKA_ST	Q9UPY8	MAPRE3	O14965	AURKA	S162	T155R	155	Missense	distal	-7	no	40.150	41.296	EPSD	CCLE	39.062	Up-regulation
Other_Aur_AURKA_ST	P04637	TP53	O14965	AURKA	S106	G108V	108	Missense	proximal	2	no	42.716	42.099	PhosphoSitePlus;EPSD	CCLE	39.062	Down-regulation
Other_Aur_AURKA_ST	Q8IX03	WWC1	O14965	AURKA	S263	W260C	260	Missense	distal	-3	no	-29.687	44.949	EPSD	CCLE	39.062	Gain
Other_Aur_AURKA_ST	Q8IX03	WWC1	O14965	AURKA	S270	S268G	268	Missense	proximal	-2	no	40.751	43.766	EPSD	CCLE	39.062	Up-regulation
Other_Aur_AURKA_ST	Q8IX03	WWC1	O14965	AURKA	S815	A813S	813	Missense	proximal	-2	no	39.603	38.083	EPSD	CCLE	39.062	Loss
Other_Aur_AURKA_ST	Q8IX03	WWC1	O14965	AURKA	S876	D880H	880	Missense	distal	4	no	42.717	42.648	EPSD	CCLE	39.062	Down-regulation
Other_Aur_AURKA_ST	P10275	AR	O14965	AURKA	S336	T338A	338	Missense	proximal	2	no	39.251	40.511	EPSD	CCLE	39.062	Up-regulation
Other_Aur_AURKA_ST	O15360	FANCA	O14965	AURKA	S1374	A1380V	1380	Missense	distal	6	no	40.044	39.947	EPSD	CCLE	39.062	Down-regulation
Other_Aur_AURKA_ST	Q9BXS6	NUSAP1	O14965	AURKA	S149	G150E	150	Missense	proximal	1	no	46.924	46.385	EPSD	CCLE	39.062	Down-regulation
Other_Aur_AURKA_ST	Q9BXS6	NUSAP1	O14965	AURKA	S154	G150E	150	Missense	distal	-4	no	40.925	42.761	EPSD	CCLE	39.062	Up-regulation
Other_Aur_AURKA_ST	P49736	MCM2	O14965	AURKA	S229	V232M	232	Missense	distal	3	no	45.165	46.619	EPSD	CCLE	39.062	Up-regulation
Other_Aur_AURKA_ST	O75496	GMNN	O14965	AURKA	S184	E182K	182	Missense	proximal	-2	no	24.979	39.122	EPSD	CCLE	39.062	Gain
Other_Aur_AURKA_ST	Q9Y6A5	TACC3	O14965	AURKA	T196	V195M	195	Missense	proximal	-1	no	41.851	43.129	EPSD	CCLE	39.062	Up-regulation
Other_Aur_AURKA_ST	Q9Y6A5	TACC3	O14965	AURKA	T196	E200K	200	Missense	distal	4	no	41.851	41.836	EPSD	CCLE	39.062	Down-regulation
Other_Aur_AURKA_ST	P25490	YY1	O14965	AURKA	S365	R363C	363	Missense	proximal	-2	no	45.539	30.242	PhosphoSitePlus	CCLE	39.062	Loss
Other_Aur_AURKA_ST	P30305	CDC25B	O14965	AURKA	T58	M59I	59	Missense	proximal	1	no	41.017	38.455	EPSD	CCLE	39.062	Loss
Other_Aur_AURKA_ST	P30305	CDC25B	O14965	AURKA	S89	S95Y	95	Missense	distal	6	no	42.061	41.991	EPSD	CCLE	39.062	Down-regulation
Other_Aur_AURKA_ST	P30305	CDC25B	O14965	AURKA	S375	R372H	372	Missense	distal	-3	no	39.179	33.406	EPSD	CCLE	39.062	Loss
Atypical_GTF2F1_GTF2F1_ST	P35269	GTF2F1	P35269	GTF2F1	S261	D255G	255	Missense	distal	-6	no	1.938	2.004	EPSD	CCLE	1.654	Up-regulation
Atypical_GTF2F1_GTF2F1_ST	P35269	GTF2F1	P35269	GTF2F1	S355	E350K	350	Missense	distal	-5	no	2.061	2.058	EPSD	CCLE	1.654	Down-regulation
Atypical_GTF2F1_GTF2F1_ST	P35269	GTF2F1	P35269	GTF2F1	S355	E349K	349	Missense	distal	-6	no	2.061	1.961	EPSD	CCLE	1.654	Down-regulation
Atypical_GTF2F1_GTF2F1_ST	P35269	GTF2F1	P35269	GTF2F1	S385	R386S	386	Missense	proximal	1	no	7.288	6.777	PhosphoSitePlus;EPSD	CCLE	1.654	Down-regulation
Atypical_GTF2F1_GTF2F1_ST	P35269	GTF2F1	P35269	GTF2F1	S385	G383D	383	Missense	proximal	-2	no	7.288	6.860	PhosphoSitePlus;EPSD	CCLE	1.654	Down-regulation
Atypical_GTF2F1_GTF2F1_ST	P35269	GTF2F1	P35269	GTF2F1	T389	R386S	386	Missense	distal	-3	no	8.110	8.135	EPSD;PhosphoSitePlus	CCLE	1.654	Up-regulation
Atypical_GTF2F1_GTF2F1_ST	P35269	GTF2F1	P35269	GTF2F1	T389	G383D	383	Missense	distal	-6	no	8.110	8.044	EPSD;PhosphoSitePlus	CCLE	1.654	Down-regulation
AGC_NDR_LATS_LATS1_ST	Q9NQS7	INCENP	O95835	LATS1	S91	R88C	88	Missense	distal	-3	no	0.003	0.000	EPSD	CCLE	0.001	Loss
AGC_NDR_LATS_LATS1_ST	Q9NQS7	INCENP	O95835	LATS1	S93	R88C	88	Missense	distal	-5	no	0.001	0.000	EPSD	CCLE	0.001	Loss
AGC_NDR_LATS_LATS1_ST	Q9NQS7	INCENP	O95835	LATS1	S446	R441T	441	Missense	distal	-5	no	0.001	0.000	EPSD	CCLE	0.001	Loss
AGC_NDR_LATS_LATS1_ST	Q9NQS7	INCENP	O95835	LATS1	T892	R887C	887	Missense	distal	-5	no	0.001	0.000	EPSD	CCLE	0.001	Loss
AGC_NDR_LATS_LATS1_ST	O95835	LATS1	O95835	LATS1	S177	R174C	174	Missense	distal	-3	no	0.003	0.000	EPSD	CCLE	0.001	Loss
AGC_NDR_LATS_LATS1_ST	P04049	RAF1	O95835	LATS1	S274	P271H	271	Missense	distal	-3	no	0.000	0.001	EPSD	CCLE	0.001	Gain
AGC_NDR_LATS_LATS1_ST	P04049	RAF1	O95835	LATS1	S357	S352L	352	Missense	distal	-5	no	0.002	0.003	EPSD	CCLE	0.001	Up-regulation
AGC_NDR_LATS_LATS1_ST	Q02241	KIF23	O95835	LATS1	S814	S814C	814	Missense	central	0	yes	0.005	0.000	PhosphoSitePlus;EPSD	CCLE	0.001	Loss
AGC_NDR_LATS_LATS1_ST	Q4VCS5	AMOT	O95835	LATS1	S264	P259Q	259	Missense	distal	-5	no	0.001	0.000	EPSD	CCLE	0.001	Loss
AGC_NDR_LATS_LATS1_ST	Q9GZV5	WWTR1	O95835	LATS1	S41	P38L	38	Missense	distal	-3	no	0.000	0.001	EPSD	CCLE	0.001	Gain
TK_PDGFR_PDGFRB_Y	P09619	PDGFRB	P09619	PDGFRB	Y579	M585I	585	Missense	distal	6	no	65.421	63.556	EPSD;PhosphoSitePlus	CCLE	43.065	Down-regulation
TK_PDGFR_PDGFRB_Y	P09619	PDGFRB	P09619	PDGFRB	Y579	G576S	576	Missense	distal	-3	no	65.421	70.239	EPSD;PhosphoSitePlus	CCLE	43.065	Up-regulation
TK_PDGFR_PDGFRB_Y	P09619	PDGFRB	P09619	PDGFRB	Y581	M585I	585	Missense	distal	4	no	62.169	62.318	EPSD;PhosphoSitePlus	CCLE	43.065	Up-regulation
TK_PDGFR_PDGFRB_Y	P09619	PDGFRB	P09619	PDGFRB	Y581	G576S	576	Missense	distal	-5	no	62.169	59.764	EPSD;PhosphoSitePlus	CCLE	43.065	Down-regulation
TK_PDGFR_PDGFRB_Y	P09619	PDGFRB	P09619	PDGFRB	Y589	M585I	585	Missense	distal	-4	no	60.161	58.516	EPSD	CCLE	43.065	Down-regulation
TK_PDGFR_PDGFRB_Y	P09619	PDGFRB	P09619	PDGFRB	Y716	N718Y	718	Missense	proximal	2	no	64.419	55.186	EPSD	CCLE	43.065	Down-regulation
TK_PDGFR_PDGFRB_Y	P09619	PDGFRB	P09619	PDGFRB	Y716	R709C	709	Missense	distal	-7	no	64.419	62.112	EPSD	CCLE	43.065	Down-regulation
TK_PDGFR_PDGFRB_Y	P09619	PDGFRB	P09619	PDGFRB	Y751	S748L	748	Missense	distal	-3	no	65.534	53.671	EPSD;PhosphoSitePlus	CCLE	43.065	Down-regulation
TK_PDGFR_PDGFRB_Y	P09619	PDGFRB	P09619	PDGFRB	Y771	N777S	777	Missense	distal	6	no	66.784	67.191	EPSD;PhosphoSitePlus	CCLE	43.065	Up-regulation
TK_PDGFR_PDGFRB_Y	P09619	PDGFRB	P09619	PDGFRB	Y775	N777S	777	Missense	proximal	2	no	66.836	67.370	EPSD;PhosphoSitePlus	CCLE	43.065	Up-regulation
TK_PDGFR_PDGFRB_Y	P09619	PDGFRB	P09619	PDGFRB	Y778	N777S	777	Missense	proximal	-1	no	65.044	63.756	EPSD;PhosphoSitePlus	CCLE	43.065	Down-regulation
TK_PDGFR_PDGFRB_Y	Q05397	PTK2	P09619	PDGFRB	Y5	P8S	8	Missense	distal	3	no	52.065	52.590	PhosphoSitePlus;EPSD	CCLE	43.065	Up-regulation
TK_PDGFR_PDGFRB_Y	P42684	ABL2	P09619	PDGFRB	Y80	V84A	84	Missense	distal	4	no	43.485	43.431	EPSD	CCLE	43.065	Down-regulation
TK_PDGFR_PDGFRB_Y	P42684	ABL2	P09619	PDGFRB	Y80	P73A	73	Missense	distal	-7	no	43.485	44.567	EPSD	CCLE	43.065	Up-regulation
TK_PDGFR_PDGFRB_Y	P42684	ABL2	P09619	PDGFRB	Y439	A445G	445	Missense	distal	6	no	62.128	62.641	EPSD	CCLE	43.065	Up-regulation
TK_PDGFR_PDGFRB_Y	P19174	PLCG1	P09619	PDGFRB	Y977	T972I	972	Missense	distal	-5	no	51.813	52.149	EPSD	CCLE	43.065	Up-regulation
TK_PDGFR_PDGFRB_Y	P19174	PLCG1	P09619	PDGFRB	Y1253	Y1253F	1253	Missense	central	0	yes	44.142	0.000	EPSD	CCLE	43.065	Loss
TK_PDGFR_PDGFRB_Y	Q07912	TNK2	P09619	PDGFRB	Y284	H289Y	289	Missense	distal	5	no	41.679	47.336	EPSD	CCLE	43.065	Gain
TK_PDGFR_PDGFRB_Y	Q07912	TNK2	P09619	PDGFRB	Y635	Y635C	635	Missense	central	0	yes	67.743	0.000	PhosphoSitePlus	CCLE	43.065	Loss
TK_FGFR_FGFR4_Y	P22455	FGFR4	P22455	FGFR4	Y754	A749S	749	Missense	distal	-5	no	4.451	4.526	PhosphoSitePlus	CCLE	1.608	Up-regulation
CMGC_CDK_CDK7_CDK7_ST	P21127	CDK11B	P50613	CDK7	T61	M58I	58	Missense	distal	-3	no	18.051	16.321	EPSD	CCLE	13.598	Down-regulation
CMGC_CDK_CDK7_CDK7_ST	P21127	CDK11B	P50613	CDK7	S65	M58I	58	Missense	distal	-7	no	12.575	14.604	EPSD	CCLE	13.598	Gain
CMGC_CDK_CDK7_CDK7_ST	P49736	MCM2	P50613	CDK7	S139	R133C	133	Missense	distal	-6	no	21.705	21.330	EPSD;PhosphoSitePlus	CCLE	13.598	Down-regulation
CMGC_CDK_CDK7_CDK7_ST	P49736	MCM2	P50613	CDK7	S139	R133P	133	Missense	distal	-6	no	21.705	21.758	EPSD;PhosphoSitePlus	CCLE	13.598	Up-regulation
CMGC_CDK_CDK7_CDK7_ST	P49736	MCM2	P50613	CDK7	S139	D143N	143	Missense	distal	4	no	21.705	19.998	EPSD;PhosphoSitePlus	CCLE	13.598	Down-regulation
CMGC_CDK_CDK7_CDK7_ST	P49736	MCM2	P50613	CDK7	S381	G383D	383	Missense	proximal	2	no	17.069	17.854	EPSD	CCLE	13.598	Up-regulation
CMGC_CDK_CDK7_CDK7_ST	P24941	CDK2	P50613	CDK7	S46	E51D	51	Missense	distal	5	no	21.025	21.195	EPSD;PhosphoSitePlus	CCLE	13.598	Up-regulation
CMGC_CDK_CDK7_CDK7_ST	P03372	ESR1	P50613	CDK7	S102	F97S	97	Missense	distal	-5	no	15.152	17.206	EPSD	CCLE	13.598	Up-regulation
CMGC_CDK_CDK7_CDK7_ST	P04637	TP53	P50613	CDK7	S33	E28Q	28	Missense	distal	-5	no	20.872	19.048	EPSD;PhosphoSitePlus	CCLE	13.598	Down-regulation
CMGC_CDK_CDK7_CDK7_ST	O00267	SUPT5H	P50613	CDK7	S36	A34T	34	Missense	proximal	-2	no	13.744	13.451	EPSD	CCLE	13.598	Loss
CMGC_CDK_CDK7_CDK7_ST	O00267	SUPT5H	P50613	CDK7	S36	E43V	43	Missense	distal	7	no	13.744	12.345	EPSD	CCLE	13.598	Loss
CMGC_CDK_CDK7_CDK7_ST	O00267	SUPT5H	P50613	CDK7	T806	G811A	811	Missense	distal	5	no	16.696	17.513	EPSD	CCLE	13.598	Up-regulation
CMGC_CDK_CDK7_CDK7_ST	O00267	SUPT5H	P50613	CDK7	S812	G811A	811	Missense	proximal	-1	no	14.513	15.041	EPSD	CCLE	13.598	Up-regulation
CMGC_CDK_CDK7_CDK7_ST	O00267	SUPT5H	P50613	CDK7	T814	G811A	811	Missense	distal	-3	no	14.065	17.695	EPSD	CCLE	13.598	Up-regulation
CMGC_CDK_CDK7_CDK7_ST	O00267	SUPT5H	P50613	CDK7	T854	G853E	853	Missense	proximal	-1	no	26.610	26.874	EPSD	CCLE	13.598	Up-regulation
CMGC_CDK_CDK7_CDK7_ST	O00267	SUPT5H	P50613	CDK7	T854	T854P	854	Missense	central	0	yes	26.610	0.000	EPSD	CCLE	13.598	Loss
CMGC_CDK_CDK7_CDK7_ST	O00267	SUPT5H	P50613	CDK7	S897	S891Y	891	Missense	distal	-6	no	15.862	15.344	EPSD	CCLE	13.598	Down-regulation
CMGC_CDK_CDK7_CDK7_ST	P50750	CDK9	P50613	CDK7	T362	R358C	358	Missense	distal	-4	no	15.027	14.979	EPSD	CCLE	13.598	Down-regulation
CMGC_CDK_CDK7_CDK7_ST	P24928	POLR2A	P50613	CDK7	S1571	P1567L	1567	Missense	distal	-4	no	14.917	14.950	EPSD	CCLE	13.598	Up-regulation
CMGC_CDK_CDK7_CDK7_ST	P24928	POLR2A	P50613	CDK7	S1616	S1616Y	1616	Missense	central	0	yes	21.364	0.000	PhosphoSitePlus;EPSD	CCLE	13.598	Loss
CMGC_CDK_CDK7_CDK7_ST	P24928	POLR2A	P50613	CDK7	S1619	S1616Y	1616	Missense	distal	-3	no	22.614	22.799	EPSD;PhosphoSitePlus	CCLE	13.598	Up-regulation
CMGC_CDK_CDK7_CDK7_ST	P24928	POLR2A	P50613	CDK7	S1621	S1616Y	1616	Missense	distal	-5	no	20.619	18.577	EPSD;PhosphoSitePlus	CCLE	13.598	Down-regulation
CMGC_CDK_CDK7_CDK7_ST	P24928	POLR2A	P50613	CDK7	S1654	T1660P	1660	Missense	distal	6	no	15.120	15.516	EPSD	CCLE	13.598	Up-regulation
CMGC_CDK_CDK7_CDK7_ST	P24928	POLR2A	P50613	CDK7	S1656	T1660P	1660	Missense	distal	4	no	12.155	13.921	EPSD	CCLE	13.598	Gain
CMGC_CDK_CDK7_CDK7_ST	P24928	POLR2A	P50613	CDK7	S1661	T1660P	1660	Missense	proximal	-1	no	14.361	14.353	EPSD	CCLE	13.598	Down-regulation
CMGC_CDK_CDK7_CDK7_ST	P24928	POLR2A	P50613	CDK7	S1710	Y1713S	1713	Missense	distal	3	no	14.197	13.526	EPSD	CCLE	13.598	Loss
CMGC_CDK_CDK7_CDK7_ST	P24928	POLR2A	P50613	CDK7	S1712	Y1713S	1713	Missense	proximal	1	no	12.047	13.666	EPSD	CCLE	13.598	Gain
CMGC_CDK_CDK7_CDK7_ST	P24928	POLR2A	P50613	CDK7	S1717	Y1713S	1713	Missense	distal	-4	no	14.306	13.876	EPSD	CCLE	13.598	Down-regulation
CMGC_CDK_CDK7_CDK7_ST	P24928	POLR2A	P50613	CDK7	S1719	Y1713S	1713	Missense	distal	-6	no	13.247	13.765	EPSD	CCLE	13.598	Gain
CMGC_CDK_CDK7_CDK7_ST	P24928	POLR2A	P50613	CDK7	S1766	Y1762H	1762	Missense	distal	-4	no	17.842	18.051	EPSD	CCLE	13.598	Up-regulation
CMGC_CDK_CDK7_CDK7_ST	P24928	POLR2A	P50613	CDK7	S1899	T1894S	1894	Missense	distal	-5	no	18.354	19.653	EPSD	CCLE	13.598	Up-regulation
CMGC_CDK_CDK7_CDK7_ST	P24928	POLR2A	P50613	CDK7	S1899	P1904S	1904	Missense	distal	5	no	18.354	19.739	EPSD	CCLE	13.598	Up-regulation
CMGC_CDK_CDK7_CDK7_ST	P24928	POLR2A	P50613	CDK7	S1913	P1914L	1914	Missense	proximal	1	no	13.635	6.164	EPSD	CCLE	13.598	Loss
CMGC_CDK_CDK7_CDK7_ST	P24928	POLR2A	P50613	CDK7	S1934	S1941F	1941	Missense	distal	7	no	9.453	14.274	EPSD	CCLE	13.598	Gain
CMGC_CDK_CDK7_CDK7_ST	P24928	POLR2A	P50613	CDK7	T1939	S1941F	1941	Missense	proximal	2	no	19.787	21.448	EPSD	CCLE	13.598	Up-regulation
CMGC_CDK_CDK7_CDK7_ST	P24928	POLR2A	P50613	CDK7	T1939	S1944Y	1944	Missense	distal	5	no	19.787	17.315	EPSD	CCLE	13.598	Down-regulation
CMGC_CDK_CDK7_CDK7_ST	P24928	POLR2A	P50613	CDK7	S1941	S1941F	1941	Missense	central	0	yes	17.772	0.000	EPSD	CCLE	13.598	Loss
CMGC_CDK_CDK7_CDK7_ST	P24928	POLR2A	P50613	CDK7	S1941	S1944Y	1944	Missense	distal	3	no	17.772	18.443	EPSD	CCLE	13.598	Up-regulation
CMGC_CDK_CDK7_CDK7_ST	P24928	POLR2A	P50613	CDK7	S1944	S1941F	1941	Missense	distal	-3	no	15.729	14.700	EPSD	CCLE	13.598	Down-regulation
CMGC_CDK_CDK7_CDK7_ST	P24928	POLR2A	P50613	CDK7	S1944	S1944Y	1944	Missense	central	0	yes	15.729	0.000	EPSD	CCLE	13.598	Loss
CMGC_CDK_CDK7_CDK7_ST	P24928	POLR2A	P50613	CDK7	S1948	S1941F	1941	Missense	distal	-7	no	15.454	18.512	EPSD	CCLE	13.598	Up-regulation
CMGC_CDK_CDK7_CDK7_ST	P24928	POLR2A	P50613	CDK7	S1948	S1944Y	1944	Missense	distal	-4	no	15.454	15.884	EPSD	CCLE	13.598	Up-regulation
CMGC_CDK_CDK7_CDK7_ST	P24928	POLR2A	P50613	CDK7	S1948	P1952A	1952	Missense	distal	4	no	15.454	14.156	EPSD	CCLE	13.598	Down-regulation
CMGC_CDK_CDK7_CDK7_ST	P24928	POLR2A	P50613	CDK7	S1951	S1944Y	1944	Missense	distal	-7	no	11.121	13.714	EPSD	CCLE	13.598	Gain
CMGC_CDK_CDK7_CDK7_ST	P10276	RARA	P50613	CDK7	S74	P79L	79	Missense	distal	5	no	15.000	15.416	EPSD	CCLE	13.598	Up-regulation
CMGC_CDK_CDK7_CDK7_ST	P10276	RARA	P50613	CDK7	S77	P79L	79	Missense	proximal	2	no	23.434	23.019	PhosphoSitePlus	CCLE	13.598	Down-regulation
CMGC_CDK_CDK7_CDK7_ST	P10276	RARA	P50613	CDK7	S445	P440L	440	Missense	distal	-5	no	15.328	13.885	EPSD	CCLE	13.598	Down-regulation
CMGC_CDK_CDK7_CDK7_ST	Q9H0D6	XRN2	P50613	CDK7	S16	S16Y	16	Missense	central	0	yes	20.912	0.000	EPSD	CCLE	13.598	Loss
CMGC_CDK_CDK7_CDK7_ST	Q9H0D6	XRN2	P50613	CDK7	T439	T439I	439	Missense	central	0	yes	25.194	0.000	PhosphoSitePlus	CCLE	13.598	Loss
CMGC_CDK_CDK7_CDK7_ST	Q9H0D6	XRN2	P50613	CDK7	S475	N468S	468	Missense	distal	-7	no	15.716	14.508	EPSD	CCLE	13.598	Down-regulation
CMGC_CDK_CDK7_CDK7_ST	Q9H0D6	XRN2	P50613	CDK7	S475	N468K	468	Missense	distal	-7	no	15.716	18.244	EPSD	CCLE	13.598	Up-regulation
CMGC_CDK_CDK7_CDK7_ST	Q9H0D6	XRN2	P50613	CDK7	S485	S485C	485	Missense	central	0	yes	16.627	0.000	EPSD	CCLE	13.598	Loss
CMGC_CDK_CDK7_CDK7_ST	Q01094	E2F1	P50613	CDK7	T96	D93G	93	Missense	distal	-3	no	18.866	19.630	EPSD	CCLE	13.598	Up-regulation
CMGC_CDK_CDK7_CDK7_ST	Q01094	E2F1	P50613	CDK7	S313	G309R	309	Missense	distal	-4	no	13.787	13.022	EPSD	CCLE	13.598	Loss
CMGC_CDK_CDK7_CDK7_ST	Q01094	E2F1	P50613	CDK7	S364	R366W	366	Missense	proximal	2	no	15.270	16.838	EPSD	CCLE	13.598	Up-regulation
CMGC_CDK_CDK7_CDK7_ST	Q01094	E2F1	P50613	CDK7	S403	L402F	402	Missense	proximal	-1	no	24.807	24.479	EPSD;PhosphoSitePlus	CCLE	13.598	Down-regulation
CMGC_CDK_CDK7_CDK7_ST	P11802	CDK4	P50613	CDK7	T172	A170T	170	Missense	proximal	-2	no	38.520	38.227	PhosphoSitePlus	CCLE	13.598	Down-regulation
CMGC_CDK_CDK7_CDK7_ST	P11802	CDK4	P50613	CDK7	S293	H296R	296	Missense	distal	3	no	15.092	15.934	EPSD	CCLE	13.598	Up-regulation
CMGC_CDK_CDK7_CDK7_ST	Q15797	SMAD1	P50613	CDK7	S206	P207S	207	Missense	proximal	1	no	24.195	15.662	PhosphoSitePlus	CCLE	13.598	Down-regulation
CMGC_CDK_CDK7_CDK7_ST	Q15797	SMAD1	P50613	CDK7	S214	P207S	207	Missense	distal	-7	no	16.769	14.691	EPSD	CCLE	13.598	Down-regulation
CMGC_CDK_CDK7_CDK7_ST	Q15797	SMAD1	P50613	CDK7	S214	S214I	214	Missense	central	0	yes	16.769	0.000	EPSD	CCLE	13.598	Loss
CMGC_CDK_CDK7_CDK7_ST	Q15797	SMAD1	P50613	CDK7	S456	P460S	460	Missense	distal	4	no	15.128	12.978	EPSD	CCLE	13.598	Loss
CMGC_CDK_CDK7_CDK7_ST	Q9NYV4	CDK12	P50613	CDK7	T82	D86Y	86	Missense	distal	4	no	13.919	11.897	EPSD	CCLE	13.598	Loss
CMGC_CDK_CDK7_CDK7_ST	Q9NYV4	CDK12	P50613	CDK7	S177	S170N	170	Missense	distal	-7	no	14.552	15.760	EPSD	CCLE	13.598	Up-regulation
CMGC_CDK_CDK7_CDK7_ST	Q9NYV4	CDK12	P50613	CDK7	S287	T289P	289	Missense	proximal	2	no	23.902	24.035	EPSD	CCLE	13.598	Up-regulation
CMGC_CDK_CDK7_CDK7_ST	Q9NYV4	CDK12	P50613	CDK7	S291	T289P	289	Missense	proximal	-2	no	16.900	17.070	EPSD	CCLE	13.598	Up-regulation
CMGC_CDK_CDK7_CDK7_ST	Q9NYV4	CDK12	P50613	CDK7	S949	L947P	947	Missense	proximal	-2	no	14.633	14.416	EPSD	CCLE	13.598	Down-regulation
CMGC_CDK_CDK7_CDK7_ST	Q9NYV4	CDK12	P50613	CDK7	S954	L947P	947	Missense	distal	-7	no	18.266	17.431	EPSD	CCLE	13.598	Down-regulation
CMGC_CDK_CDK7_CDK7_ST	Q9NYV4	CDK12	P50613	CDK7	S954	V959M	959	Missense	distal	5	no	18.266	19.082	EPSD	CCLE	13.598	Up-regulation
CMGC_CDK_CDK7_CDK7_ST	Q9NYV4	CDK12	P50613	CDK7	S1063	E1058K	1058	Missense	distal	-5	no	14.709	12.990	EPSD	CCLE	13.598	Loss
CMGC_CDK_CDK7_CDK7_ST	Q9NYV4	CDK12	P50613	CDK7	T1244	E1251D	1251	Missense	distal	7	no	18.395	15.704	EPSD	CCLE	13.598	Down-regulation
AGC_NDR_NDR_STK38_ST	Q15208	STK38	Q15208	STK38	T270	K267R	267	Missense	distal	-3	no	-0.172	0.334	EPSD	CCLE	0.133	Gain
AGC_NDR_NDR_STK38_ST	Q02241	KIF23	Q15208	STK38	S814	S814C	814	Missense	central	0	yes	2.152	0.000	PhosphoSitePlus;EPSD	CCLE	0.133	Loss
AGC_NDR_NDR_STK38_ST	Q02241	KIF23	Q15208	STK38	T843	H837R	837	Missense	distal	-6	no	0.224	0.217	EPSD	CCLE	0.133	Down-regulation
CAMK_CAMKL_AMPK_PRKAA1_ST	Q9Y478	PRKAB1	Q13131	PRKAA1	S24	R22K	22	Missense	proximal	-2	no	60.885	62.263	EPSD;PhosphoSitePlus	CCLE	56.683	Up-regulation
CAMK_CAMKL_AMPK_PRKAA1_ST	Q9Y478	PRKAB1	Q13131	PRKAA1	S25	R22K	22	Missense	distal	-3	no	60.119	55.478	EPSD	CCLE	56.683	Loss
CAMK_CAMKL_AMPK_PRKAA1_ST	Q9Y478	PRKAB1	Q13131	PRKAA1	S108	H109Q	109	Missense	proximal	1	no	64.453	60.575	PhosphoSitePlus;EPSD	CCLE	56.683	Down-regulation
CAMK_CAMKL_AMPK_PRKAA1_ST	Q9Y478	PRKAB1	Q13131	PRKAA1	T158	F163C	163	Missense	distal	5	no	62.227	62.391	EPSD;PhosphoSitePlus	CCLE	56.683	Up-regulation
CAMK_CAMKL_AMPK_PRKAA1_ST	P10636	MAPT	Q13131	PRKAA1	T63	A66V	66	Missense	distal	3	no	54.410	59.286	EPSD	CCLE	56.683	Gain
CAMK_CAMKL_AMPK_PRKAA1_ST	P10636	MAPT	Q13131	PRKAA1	S171	P170F	170	Missense	proximal	-1	no	59.279	59.278	EPSD	CCLE	56.683	Down-regulation
CAMK_CAMKL_AMPK_PRKAA1_ST	P10636	MAPT	Q13131	PRKAA1	S171	G174A	174	Missense	distal	3	no	59.279	54.097	EPSD	CCLE	56.683	Loss
CAMK_CAMKL_AMPK_PRKAA1_ST	P10636	MAPT	Q13131	PRKAA1	S214	D221Y	221	Missense	distal	7	no	71.752	73.220	EPSD;PhosphoSitePlus	CCLE	56.683	Up-regulation
CAMK_CAMKL_AMPK_PRKAA1_ST	P10636	MAPT	Q13131	PRKAA1	T403	K405R	405	Missense	proximal	2	no	58.125	58.009	EPSD	CCLE	56.683	Down-regulation
CAMK_CAMKL_AMPK_PRKAA1_ST	P10636	MAPT	Q13131	PRKAA1	S516	R511H	511	Missense	distal	-5	no	62.451	57.071	EPSD	CCLE	56.683	Down-regulation
CAMK_CAMKL_AMPK_PRKAA1_ST	P10636	MAPT	Q13131	PRKAA1	S516	G518S	518	Missense	proximal	2	no	62.451	62.960	EPSD	CCLE	56.683	Up-regulation
CAMK_CAMKL_AMPK_PRKAA1_ST	P10636	MAPT	Q13131	PRKAA1	T522	R526L	526	Missense	distal	4	no	53.789	59.271	EPSD	CCLE	56.683	Gain
CAMK_CAMKL_AMPK_PRKAA1_ST	P10636	MAPT	Q13131	PRKAA1	T529	R526L	526	Missense	distal	-3	no	61.774	51.807	EPSD	CCLE	56.683	Loss
CAMK_CAMKL_AMPK_PRKAA1_ST	P10636	MAPT	Q13131	PRKAA1	S531	R526L	526	Missense	distal	-5	no	64.022	65.199	EPSD	CCLE	56.683	Up-regulation
CAMK_CAMKL_AMPK_PRKAA1_ST	P10636	MAPT	Q13131	PRKAA1	S552	R559H	559	Missense	distal	7	no	57.936	57.209	EPSD	CCLE	56.683	Down-regulation
CAMK_CAMKL_AMPK_PRKAA1_ST	P10636	MAPT	Q13131	PRKAA1	T562	R559H	559	Missense	distal	-3	no	63.536	55.680	EPSD	CCLE	56.683	Loss
CAMK_CAMKL_AMPK_PRKAA1_ST	P10636	MAPT	Q13131	PRKAA1	S575	K574N	574	Missense	proximal	-1	no	69.683	69.749	EPSD	CCLE	56.683	Up-regulation
CAMK_CAMKL_AMPK_PRKAA1_ST	P10636	MAPT	Q13131	PRKAA1	S579	K574N	574	Missense	distal	-5	no	67.909	53.066	EPSD	CCLE	56.683	Loss
CAMK_CAMKL_AMPK_PRKAA1_ST	P10636	MAPT	Q13131	PRKAA1	S713	G706V	706	Missense	distal	-7	no	57.057	55.259	EPSD	CCLE	56.683	Loss
CAMK_CAMKL_AMPK_PRKAA1_ST	P10636	MAPT	Q13131	PRKAA1	S713	S717C	717	Missense	distal	4	no	57.057	37.309	EPSD	CCLE	56.683	Loss
CAMK_CAMKL_AMPK_PRKAA1_ST	P10636	MAPT	Q13131	PRKAA1	S726	S721C	721	Missense	distal	-5	no	62.356	64.007	EPSD	CCLE	56.683	Up-regulation
CAMK_CAMKL_AMPK_PRKAA1_ST	P10636	MAPT	Q13131	PRKAA1	S726	H724R	724	Missense	proximal	-2	no	62.356	65.077	EPSD	CCLE	56.683	Up-regulation
CAMK_CAMKL_AMPK_PRKAA1_ST	Q7Z3C6	ATG9A	Q13131	PRKAA1	S761	R758P	758	Missense	distal	-3	no	63.081	54.221	PhosphoSitePlus	CCLE	56.683	Loss
CAMK_CAMKL_AMPK_PRKAA1_ST	Q7Z3C6	ATG9A	Q13131	PRKAA1	S761	P757S	757	Missense	distal	-4	no	63.081	64.324	PhosphoSitePlus	CCLE	56.683	Up-regulation
CAMK_CAMKL_AMPK_PRKAA1_ST	Q7Z628	NET1	Q13131	PRKAA1	S51	R47P	47	Missense	distal	-4	no	67.889	65.581	EPSD	CCLE	56.683	Down-regulation
CAMK_CAMKL_AMPK_PRKAA1_ST	Q8IY63	AMOTL1	Q13131	PRKAA1	S793	A798E	798	Missense	distal	5	no	58.596	58.504	PhosphoSitePlus	CCLE	56.683	Down-regulation
CAMK_CAMKL_AMPK_PRKAA1_ST	Q13131	PRKAA1	Q13131	PRKAA1	S176	M174I	174	Missense	proximal	-2	no	63.123	63.659	EPSD	CCLE	56.683	Up-regulation
CAMK_CAMKL_AMPK_PRKAA1_ST	Q13131	PRKAA1	Q13131	PRKAA1	S360	S356N	356	Missense	distal	-4	no	57.590	52.790	EPSD;PhosphoSitePlus	CCLE	56.683	Loss
CAMK_CAMKL_AMPK_PRKAA1_ST	Q13131	PRKAA1	Q13131	PRKAA1	S467	Q461R	461	Missense	distal	-6	no	60.859	60.501	EPSD	CCLE	56.683	Down-regulation
CAMK_CAMKL_AMPK_PRKAA1_ST	Q13131	PRKAA1	Q13131	PRKAA1	S494	S494L	494	Missense	central	0	yes	60.164	0.000	PhosphoSitePlus;EPSD	CCLE	56.683	Loss
CAMK_CAMKL_AMPK_PRKAA1_ST	Q13131	PRKAA1	Q13131	PRKAA1	S494	S494W	494	Missense	central	0	yes	60.164	0.000	PhosphoSitePlus;EPSD	CCLE	56.683	Loss
CAMK_CAMKL_AMPK_PRKAA1_ST	Q13131	PRKAA1	Q13131	PRKAA1	S496	S494L	494	Missense	proximal	-2	no	64.289	61.863	EPSD;PhosphoSitePlus	CCLE	56.683	Down-regulation
CAMK_CAMKL_AMPK_PRKAA1_ST	Q13131	PRKAA1	Q13131	PRKAA1	S496	S494W	494	Missense	proximal	-2	no	64.289	60.710	EPSD;PhosphoSitePlus	CCLE	56.683	Down-regulation
CAMK_CAMKL_AMPK_PRKAA1_ST	Q13131	PRKAA1	Q13131	PRKAA1	S517	L521V	521	Missense	distal	4	no	59.979	55.482	EPSD	CCLE	56.683	Loss
CAMK_CAMKL_AMPK_PRKAA1_ST	Q15036	SNX17	Q13131	PRKAA1	S333	R339Q	339	Missense	distal	6	no	56.514	56.943	EPSD	CCLE	56.683	Gain
CAMK_CAMKL_AMPK_PRKAA1_ST	Q15036	SNX17	Q13131	PRKAA1	S335	R339Q	339	Missense	distal	4	no	58.513	54.430	EPSD	CCLE	56.683	Loss
CAMK_CAMKL_AMPK_PRKAA1_ST	Q9UQL6	HDAC5	Q13131	PRKAA1	S16	G9R	9	Missense	distal	-7	no	63.105	61.690	EPSD	CCLE	56.683	Down-regulation
CAMK_CAMKL_AMPK_PRKAA1_ST	Q9UQL6	HDAC5	Q13131	PRKAA1	S1108	E1113Q	1113	Missense	distal	5	no	60.786	60.912	EPSD	CCLE	56.683	Up-regulation
CAMK_CAMKL_AMPK_PRKAA1_ST	Q9UQL6	HDAC5	Q13131	PRKAA1	S1108	S1108G	1108	Missense	central	0	yes	60.786	0.000	EPSD	CCLE	56.683	Loss
CAMK_CAMKL_AMPK_PRKAA1_ST	P29474	NOS3	Q13131	PRKAA1	T785	Q788H	788	Missense	distal	3	no	60.258	55.295	EPSD	CCLE	56.683	Loss
CAMK_CAMKL_AMPK_PRKAA1_ST	P50552	VASP	Q13131	PRKAA1	T278	T278M	278	Missense	central	0	yes	60.929	0.000	PhosphoSitePlus	CCLE	56.683	Loss
CAMK_CAMKL_AMPK_PRKAA1_ST	P50552	VASP	Q13131	PRKAA1	S322	S324C	324	Missense	proximal	2	no	67.825	66.528	EPSD	CCLE	56.683	Down-regulation
CAMK_CAMKL_AMPK_PRKAA1_ST	P50552	VASP	Q13131	PRKAA1	T328	S324C	324	Missense	distal	-4	no	53.024	58.399	EPSD	CCLE	56.683	Gain
CAMK_CAMKL_AMPK_PRKAA1_ST	Q13085	ACACA	Q13131	PRKAA1	S835	P837S	837	Missense	proximal	2	no	58.870	58.326	EPSD	CCLE	56.683	Down-regulation
CAMK_CAMKL_AMPK_PRKAA1_ST	Q13085	ACACA	Q13131	PRKAA1	S841	P837S	837	Missense	distal	-4	no	62.915	64.158	EPSD	CCLE	56.683	Up-regulation
CAMK_CAMKL_AMPK_PRKAA1_ST	Q13085	ACACA	Q13131	PRKAA1	S977	M983V	983	Missense	distal	6	no	67.169	66.950	EPSD	CCLE	56.683	Down-regulation
CAMK_CAMKL_AMPK_PRKAA1_ST	Q13085	ACACA	Q13131	PRKAA1	S1201	S1204C	1204	Missense	distal	3	no	63.167	61.336	EPSD	CCLE	56.683	Down-regulation
CAMK_CAMKL_AMPK_PRKAA1_ST	Q13085	ACACA	Q13131	PRKAA1	S1201	S1203A	1203	Missense	proximal	2	no	63.167	62.967	EPSD	CCLE	56.683	Down-regulation
CAMK_CAMKL_AMPK_PRKAA1_ST	Q13085	ACACA	Q13131	PRKAA1	S1216	S1216I	1216	Missense	central	0	yes	58.049	0.000	EPSD	CCLE	56.683	Loss
CAMK_CAMKL_AMPK_PRKAA1_ST	Q13085	ACACA	Q13131	PRKAA1	T1227	F1226L	1226	Missense	proximal	-1	no	57.299	57.371	EPSD	CCLE	56.683	Up-regulation
CAMK_CAMKL_AMPK_PRKAA1_ST	Q13085	ACACA	Q13131	PRKAA1	T1265	T1272M	1272	Missense	distal	7	no	60.748	59.033	EPSD	CCLE	56.683	Down-regulation
CAMK_CAMKL_AMPK_PRKAA1_ST	Q13085	ACACA	Q13131	PRKAA1	S1438	S1438C	1438	Missense	central	0	yes	63.969	0.000	EPSD	CCLE	56.683	Loss
CAMK_CAMKL_AMPK_PRKAA1_ST	Q13085	ACACA	Q13131	PRKAA1	S1501	V1508I	1508	Missense	distal	7	no	66.166	67.364	EPSD	CCLE	56.683	Up-regulation
CAMK_CAMKL_AMPK_PRKAA1_ST	Q13085	ACACA	Q13131	PRKAA1	S1844	R1837I	1837	Missense	distal	-7	no	57.047	55.691	EPSD	CCLE	56.683	Loss
CAMK_CAMKL_AMPK_PRKAA1_ST	Q13085	ACACA	Q13131	PRKAA1	S1908	S1905R	1905	Missense	distal	-3	no	52.274	61.670	EPSD	CCLE	56.683	Gain
CAMK_CAMKL_AMPK_PRKAA1_ST	P23458	JAK1	Q13131	PRKAA1	S228	S228C	228	Missense	central	0	yes	57.763	0.000	EPSD	CCLE	56.683	Loss
CAMK_CAMKL_AMPK_PRKAA1_ST	Q13950	RUNX2	Q13131	PRKAA1	S28	S32R	32	Missense	distal	4	no	57.931	59.037	EPSD	CCLE	56.683	Up-regulation
CAMK_CAMKL_AMPK_PRKAA1_ST	Q13950	RUNX2	Q13131	PRKAA1	S118	C123Y	123	Missense	distal	5	no	64.740	64.793	PhosphoSitePlus	CCLE	56.683	Up-regulation
CAMK_CAMKL_AMPK_PRKAA1_ST	Q13950	RUNX2	Q13131	PRKAA1	S196	T200I	200	Missense	distal	4	no	74.997	79.020	EPSD	CCLE	56.683	Up-regulation
CAMK_CAMKL_AMPK_PRKAA1_ST	Q13950	RUNX2	Q13131	PRKAA1	S298	A291T	291	Missense	distal	-7	no	60.621	61.470	EPSD	CCLE	56.683	Up-regulation
CAMK_CAMKL_AMPK_PRKAA1_ST	Q13950	RUNX2	Q13131	PRKAA1	S298	Q301K	301	Missense	distal	3	no	60.621	60.634	EPSD	CCLE	56.683	Up-regulation
CAMK_CAMKL_AMPK_PRKAA1_ST	Q13950	RUNX2	Q13131	PRKAA1	S465	P460L	460	Missense	distal	-5	no	56.461	61.201	EPSD	CCLE	56.683	Gain
CAMK_CAMKL_AMPK_PRKAA1_ST	Q9H0B6	KLC2	Q13131	PRKAA1	S445	T451S	451	Missense	distal	6	no	61.611	61.677	EPSD	CCLE	56.683	Up-regulation
CAMK_CAMKL_AMPK_PRKAA1_ST	P09874	PARP1	Q13131	PRKAA1	S257	K262R	262	Missense	distal	5	no	65.400	65.459	EPSD	CCLE	56.683	Up-regulation
CAMK_CAMKL_AMPK_PRKAA1_ST	P09874	PARP1	Q13131	PRKAA1	S343	R340G	340	Missense	distal	-3	no	60.884	51.849	EPSD	CCLE	56.683	Loss
CAMK_CAMKL_AMPK_PRKAA1_ST	P09874	PARP1	Q13131	PRKAA1	T361	A367D	367	Missense	distal	6	no	60.148	59.754	EPSD	CCLE	56.683	Down-regulation
CAMK_CAMKL_AMPK_PRKAA1_ST	P09874	PARP1	Q13131	PRKAA1	S606	I611V	611	Missense	distal	5	no	58.313	58.296	EPSD	CCLE	56.683	Down-regulation
CAMK_CAMKL_AMPK_PRKAA1_ST	P09874	PARP1	Q13131	PRKAA1	S606	E608K	608	Missense	proximal	2	no	58.313	57.920	EPSD	CCLE	56.683	Down-regulation
CAMK_CAMKL_AMPK_PRKAA1_ST	O00418	EEF2K	Q13131	PRKAA1	S359	S359C	359	Missense	central	0	yes	60.593	0.000	EPSD	CCLE	56.683	Loss
CAMK_CAMKL_AMPK_PRKAA1_ST	O00418	EEF2K	Q13131	PRKAA1	S398	S404N	404	Missense	distal	6	no	62.228	62.110	PhosphoSitePlus	CCLE	56.683	Down-regulation
CAMK_CAMKL_AMPK_PRKAA1_ST	O60825	PFKFB2	Q13131	PRKAA1	S214	N220H	220	Missense	distal	6	no	57.521	57.637	EPSD	CCLE	56.683	Up-regulation
CAMK_CAMKL_AMPK_PRKAA1_ST	P13569	CFTR	Q13131	PRKAA1	S256	S263L	263	Missense	distal	7	no	56.867	56.909	EPSD	CCLE	56.683	Up-regulation
CAMK_CAMKL_AMPK_PRKAA1_ST	P13569	CFTR	Q13131	PRKAA1	S686	E692K	692	Missense	distal	6	no	67.697	67.469	EPSD	CCLE	56.683	Down-regulation
CAMK_CAMKL_AMPK_PRKAA1_ST	P13569	CFTR	Q13131	PRKAA1	S813	G817C	817	Missense	distal	4	no	62.646	43.994	EPSD;PhosphoSitePlus	CCLE	56.683	Loss
CAMK_CAMKL_AMPK_PRKAA1_ST	P13569	CFTR	Q13131	PRKAA1	S1248	T1246P	1246	Missense	proximal	-2	no	65.680	68.912	EPSD	CCLE	56.683	Up-regulation
CAMK_CAMKL_AMPK_PRKAA1_ST	O43524	FOXO3	Q13131	PRKAA1	S30	R27G	27	Missense	distal	-3	no	62.267	53.232	EPSD;PhosphoSitePlus	CCLE	56.683	Loss
CAMK_CAMKL_AMPK_PRKAA1_ST	O43524	FOXO3	Q13131	PRKAA1	T32	R27G	27	Missense	distal	-5	no	60.858	57.849	EPSD	CCLE	56.683	Down-regulation
CAMK_CAMKL_AMPK_PRKAA1_ST	O43524	FOXO3	Q13131	PRKAA1	S161	D164N	164	Missense	distal	3	no	58.083	59.336	EPSD	CCLE	56.683	Up-regulation
CAMK_CAMKL_AMPK_PRKAA1_ST	O43524	FOXO3	Q13131	PRKAA1	S666	P672S	672	Missense	distal	6	no	58.441	58.456	EPSD	CCLE	56.683	Up-regulation
CAMK_CAMKL_AMPK_PRKAA1_ST	P46527	CDKN1B	Q13131	PRKAA1	S83	F87L	87	Missense	distal	4	no	58.576	62.771	EPSD	CCLE	56.683	Up-regulation
CAMK_CAMKL_AMPK_PRKAA1_ST	P46527	CDKN1B	Q13131	PRKAA1	S83	Y89C	89	Missense	distal	6	no	58.576	58.713	EPSD	CCLE	56.683	Up-regulation
CAMK_CAMKL_AMPK_PRKAA1_ST	P08151	GLI1	Q13131	PRKAA1	S204	P202H	202	Missense	proximal	-2	no	57.771	53.261	EPSD	CCLE	56.683	Loss
CAMK_CAMKL_AMPK_PRKAA1_ST	P08151	GLI1	Q13131	PRKAA1	S204	G206C	206	Missense	proximal	2	no	57.771	56.983	EPSD	CCLE	56.683	Down-regulation
CAMK_CAMKL_AMPK_PRKAA1_ST	P08151	GLI1	Q13131	PRKAA1	S408	S410F	410	Missense	proximal	2	no	63.799	63.506	PhosphoSitePlus	CCLE	56.683	Down-regulation
CAMK_CAMKL_AMPK_PRKAA1_ST	P08151	GLI1	Q13131	PRKAA1	S545	I549S	549	Missense	distal	4	no	73.952	70.441	EPSD	CCLE	56.683	Down-regulation
CAMK_CAMKL_AMPK_PRKAA1_ST	Q16576	RBBP7	Q13131	PRKAA1	T416	T417A	417	Missense	proximal	1	no	57.678	57.126	EPSD	CCLE	56.683	Down-regulation
CAMK_CAMKL_AMPK_PRKAA1_ST	Q9BZL4	PPP1R12C	Q13131	PRKAA1	S427	S427I	427	Missense	central	0	yes	61.052	0.000	EPSD	CCLE	56.683	Loss
CAMK_CAMKL_AMPK_PRKAA1_ST	Q9BZL4	PPP1R12C	Q13131	PRKAA1	S452	S453F	453	Missense	proximal	1	no	66.941	71.481	PhosphoSitePlus	CCLE	56.683	Up-regulation
CAMK_CAMKL_AMPK_PRKAA1_ST	Q9BZL4	PPP1R12C	Q13131	PRKAA1	S452	R449C	449	Missense	distal	-3	no	66.941	52.793	PhosphoSitePlus	CCLE	56.683	Loss
CAMK_CAMKL_AMPK_PRKAA1_ST	Q9BZL4	PPP1R12C	Q13131	PRKAA1	S486	S483F	483	Missense	distal	-3	no	57.188	57.336	EPSD	CCLE	56.683	Up-regulation
CAMK_CAMKL_AMPK_PRKAA1_ST	Q9BZL4	PPP1R12C	Q13131	PRKAA1	S559	Q561K	561	Missense	proximal	2	no	63.273	63.865	EPSD	CCLE	56.683	Up-regulation
CAMK_CAMKL_AMPK_PRKAA1_ST	P04637	TP53	Q13131	PRKAA1	S106	G108V	108	Missense	proximal	2	no	57.242	58.698	EPSD	CCLE	56.683	Up-regulation
CAMK_CAMKL_AMPK_PRKAA1_ST	Q92538	GBF1	Q13131	PRKAA1	S670	V668G	668	Missense	proximal	-2	no	57.868	54.556	EPSD	CCLE	56.683	Loss
CAMK_CAMKL_AMPK_PRKAA1_ST	Q92538	GBF1	Q13131	PRKAA1	T1337	D1340N	1340	Missense	distal	3	no	65.333	66.586	PhosphoSitePlus	CCLE	56.683	Up-regulation
CAMK_CAMKL_AMPK_PRKAA1_ST	P19429	TNNI3	Q13131	PRKAA1	T119	I114T	114	Missense	distal	-5	no	58.629	52.387	EPSD	CCLE	56.683	Loss
CAMK_CAMKL_AMPK_PRKAA1_ST	P19429	TNNI3	Q13131	PRKAA1	T119	D113Y	113	Missense	distal	-6	no	58.629	53.746	EPSD	CCLE	56.683	Loss
CAMK_CAMKL_AMPK_PRKAA1_ST	Q14457	BECN1	Q13131	PRKAA1	S90	S93N	93	Missense	distal	3	no	59.533	61.527	EPSD	CCLE	56.683	Up-regulation
CAMK_CAMKL_AMPK_PRKAA1_ST	Q14457	BECN1	Q13131	PRKAA1	S96	S93N	93	Missense	distal	-3	no	58.267	61.726	EPSD;PhosphoSitePlus	CCLE	56.683	Up-regulation
CAMK_CAMKL_AMPK_PRKAA1_ST	Q8N122	RPTOR	Q13131	PRKAA1	S721	R727G	727	Missense	distal	6	no	59.616	59.495	EPSD	CCLE	56.683	Down-regulation
CAMK_CAMKL_AMPK_PRKAA1_ST	Q8N122	RPTOR	Q13131	PRKAA1	S722	R727G	727	Missense	distal	5	no	64.569	64.490	EPSD;PhosphoSitePlus	CCLE	56.683	Down-regulation
CAMK_CAMKL_AMPK_PRKAA1_ST	Q8N122	RPTOR	Q13131	PRKAA1	T731	R727G	727	Missense	distal	-4	no	59.290	55.682	EPSD	CCLE	56.683	Loss
CAMK_CAMKL_AMPK_PRKAA1_ST	Q13621	SLC12A1	Q13131	PRKAA1	S130	N127K	127	Missense	distal	-3	no	62.602	63.897	PhosphoSitePlus	CCLE	56.683	Up-regulation
CAMK_CAMKL_AMPK_PRKAA1_ST	Q13621	SLC12A1	Q13131	PRKAA1	S885	T882K	882	Missense	distal	-3	no	56.974	66.444	EPSD	CCLE	56.683	Up-regulation
CAMK_CAMKL_AMPK_PRKAA1_ST	O75925	PIAS1	Q13131	PRKAA1	S476	C481Y	481	Missense	distal	5	no	58.365	58.418	EPSD	CCLE	56.683	Up-regulation
CAMK_CAMKL_AMPK_PRKAA1_ST	O75925	PIAS1	Q13131	PRKAA1	T480	C481Y	481	Missense	proximal	1	no	55.073	58.052	EPSD	CCLE	56.683	Gain
CAMK_CAMKL_AMPK_PRKAA1_ST	O75925	PIAS1	Q13131	PRKAA1	S485	C481Y	481	Missense	distal	-4	no	62.320	54.084	EPSD	CCLE	56.683	Loss
CAMK_CAMKL_AMPK_PRKAA1_ST	Q13362	PPP2R5C	Q13131	PRKAA1	S497	D502N	502	Missense	distal	5	no	63.865	63.720	EPSD	CCLE	56.683	Down-regulation
CAMK_CAMKL_AMPK_PRKAA1_ST	Q13362	PPP2R5C	Q13131	PRKAA1	T505	D502N	502	Missense	distal	-3	no	54.694	58.610	EPSD	CCLE	56.683	Gain
CAMK_CAMKL_AMPK_PRKAA1_ST	P41235	HNF4A	Q13131	PRKAA1	S313	R312C	312	Missense	proximal	-1	no	57.846	57.993	PhosphoSitePlus	CCLE	56.683	Up-regulation
CAMK_CAMKL_AMPK_PRKAA1_ST	P49674	CSNK1E	Q13131	PRKAA1	T407	H413R	413	Missense	distal	6	no	57.400	57.295	EPSD	CCLE	56.683	Down-regulation
CAMK_CAMKL_AMPK_PRKAA1_ST	P04626	ERBB2	Q13131	PRKAA1	S1174	V1181I	1181	Missense	distal	7	no	56.457	57.655	EPSD	CCLE	56.683	Gain
CAMK_CAMKL_AMPK_PRKAA1_ST	Q14694	USP10	Q13131	PRKAA1	S109	D114N	114	Missense	distal	5	no	58.285	58.141	EPSD	CCLE	56.683	Down-regulation
CAMK_CAMKL_AMPK_PRKAA1_ST	Q14694	USP10	Q13131	PRKAA1	S331	S337I	337	Missense	distal	6	no	57.713	57.390	EPSD	CCLE	56.683	Down-regulation
CAMK_CAMKL_AMPK_PRKAA1_ST	Q9BUB5	MKNK1	Q13131	PRKAA1	S437	R443L	443	Missense	distal	6	no	60.055	60.295	EPSD	CCLE	56.683	Up-regulation
CAMK_CAMKL_AMPK_PRKAA1_ST	O15360	FANCA	Q13131	PRKAA1	S850	Q851H	851	Missense	proximal	1	no	59.552	63.430	EPSD	CCLE	56.683	Up-regulation
CAMK_CAMKL_AMPK_PRKAA1_ST	O95239	KIF4A	Q13131	PRKAA1	S634	S634A	634	Missense	central	0	yes	58.391	0.000	EPSD	CCLE	56.683	Loss
CAMK_CAMKL_AMPK_PRKAA1_ST	O95239	KIF4A	Q13131	PRKAA1	S1178	V1173M	1173	Missense	distal	-5	no	56.142	60.838	EPSD	CCLE	56.683	Gain
CAMK_CAMKL_AMPK_PRKAA1_ST	O75385	ULK1	Q13131	PRKAA1	S495	A491T	491	Missense	distal	-4	no	66.399	65.544	EPSD	CCLE	56.683	Down-regulation
CAMK_CAMKL_AMPK_PRKAA1_ST	O75385	ULK1	Q13131	PRKAA1	S495	G499C	499	Missense	distal	4	no	66.399	47.747	EPSD	CCLE	56.683	Loss
CAMK_CAMKL_AMPK_PRKAA1_ST	Q9BU19	ZNF692	Q13131	PRKAA1	S63	G65D	65	Missense	proximal	2	no	60.157	61.309	EPSD	CCLE	56.683	Up-regulation
CAMK_CAMKL_AMPK_PRKAA1_ST	Q9BU19	ZNF692	Q13131	PRKAA1	S63	G65C	65	Missense	proximal	2	no	60.157	59.370	EPSD	CCLE	56.683	Down-regulation
CAMK_CAMKL_AMPK_PRKAA1_ST	Q9BU19	ZNF692	Q13131	PRKAA1	T119	A116V	116	Missense	distal	-3	no	65.670	68.113	EPSD	CCLE	56.683	Up-regulation
CAMK_CAMKL_AMPK_PRKAA1_ST	Q9BU19	ZNF692	Q13131	PRKAA1	S153	S146C	146	Missense	distal	-7	no	60.384	57.996	EPSD	CCLE	56.683	Down-regulation
CAMK_CAMKL_AMPK_PRKAA1_ST	O15350	TP73	Q13131	PRKAA1	T27	P24L	24	Missense	distal	-3	no	69.200	68.093	EPSD	CCLE	56.683	Down-regulation
CAMK_CAMKL_AMPK_PRKAA1_ST	O15350	TP73	Q13131	PRKAA1	S223	R216H	216	Missense	distal	-7	no	58.421	55.397	EPSD	CCLE	56.683	Loss
CAMK_CAMKL_AMPK_PRKAA1_ST	O15350	TP73	Q13131	PRKAA1	S388	Q392R	392	Missense	distal	4	no	54.390	58.473	EPSD	CCLE	56.683	Gain
CAMK_CAMKL_AMPK_PRKAA1_ST	O15350	TP73	Q13131	PRKAA1	S426	P425L	425	Missense	proximal	-1	no	65.075	65.146	PhosphoSitePlus	CCLE	56.683	Up-regulation
CAMK_CAMKL_AMPK_PRKAA1_ST	O15350	TP73	Q13131	PRKAA1	S471	S477L	477	Missense	distal	6	no	61.982	62.116	EPSD	CCLE	56.683	Up-regulation
CAMK_CAMKL_AMPK_PRKAA1_ST	Q05469	LIPE	Q13131	PRKAA1	S607	V601I	601	Missense	distal	-6	no	63.227	61.737	EPSD	CCLE	56.683	Down-regulation
CAMK_CAMKL_AMPK_PRKAA1_ST	Q05469	LIPE	Q13131	PRKAA1	T1052	T1052A	1052	Missense	central	0	yes	61.735	0.000	EPSD	CCLE	56.683	Loss
CAMK_CAMKL_AMPK_PRKAA1_ST	Q6N021	TET2	Q13131	PRKAA1	T1331	L1332H	1332	Missense	proximal	1	no	60.237	63.173	EPSD	CCLE	56.683	Up-regulation
CAMK_CAMKL_AMPK_PRKAA1_ST	Q09472	EP300	Q13131	PRKAA1	S89	M95T	95	Missense	distal	6	no	74.231	74.058	PhosphoSitePlus	CCLE	56.683	Down-regulation
CAMK_CAMKL_AMPK_PRKAA1_ST	Q09472	EP300	Q13131	PRKAA1	S1849	P1855L	1855	Missense	distal	6	no	59.898	60.046	EPSD	CCLE	56.683	Up-regulation
CAMK_CAMKL_AMPK_PRKAA1_ST	Q09472	EP300	Q13131	PRKAA1	S1897	Q1898R	1898	Missense	proximal	1	no	62.414	63.293	EPSD	CCLE	56.683	Up-regulation
CAMK_CAMKL_AMPK_PRKAA1_ST	Q09472	EP300	Q13131	PRKAA1	S1897	A1902V	1902	Missense	distal	5	no	62.414	62.314	EPSD	CCLE	56.683	Down-regulation
CAMK_CAMKL_AMPK_PRKAA1_ST	Q86TI0	TBC1D1	Q13131	PRKAA1	S513	L512F	512	Missense	proximal	-1	no	57.727	57.655	EPSD	CCLE	56.683	Down-regulation
CAMK_CAMKL_AMPK_PRKAA1_ST	Q86TI0	TBC1D1	Q13131	PRKAA1	S558	S559F	559	Missense	proximal	1	no	53.378	57.918	EPSD	CCLE	56.683	Gain
CAMK_CAMKL_AMPK_PRKAA1_ST	P26358	DNMT1	Q13131	PRKAA1	T137	T137R	137	Missense	central	0	yes	61.124	0.000	EPSD	CCLE	56.683	Loss
CAMK_CAMKL_AMPK_PRKAA1_ST	P26358	DNMT1	Q13131	PRKAA1	S143	T137R	137	Missense	distal	-6	no	65.756	65.761	EPSD	CCLE	56.683	Up-regulation
CAMK_CAMKL_AMPK_PRKAA1_ST	P26358	DNMT1	Q13131	PRKAA1	T208	E211A	211	Missense	distal	3	no	59.207	56.196	EPSD	CCLE	56.683	Loss
CAMK_CAMKL_AMPK_PRKAA1_ST	P26358	DNMT1	Q13131	PRKAA1	S209	E211A	211	Missense	proximal	2	no	69.962	69.159	EPSD	CCLE	56.683	Down-regulation
CAMK_CAMKL_AMPK_PRKAA1_ST	P26358	DNMT1	Q13131	PRKAA1	S288	K291E	291	Missense	distal	3	no	57.041	55.316	EPSD	CCLE	56.683	Loss
CAMK_CAMKL_AMPK_PRKAA1_ST	P26358	DNMT1	Q13131	PRKAA1	S288	K285Q	285	Missense	distal	-3	no	57.041	53.738	EPSD	CCLE	56.683	Loss
CAMK_CAMKL_AMPK_PRKAA1_ST	P26358	DNMT1	Q13131	PRKAA1	T327	T333M	333	Missense	distal	6	no	60.113	60.287	EPSD	CCLE	56.683	Up-regulation
CAMK_CAMKL_AMPK_PRKAA1_ST	P26358	DNMT1	Q13131	PRKAA1	T328	K335R	335	Missense	distal	7	no	59.040	59.927	EPSD	CCLE	56.683	Up-regulation
CAMK_CAMKL_AMPK_PRKAA1_ST	P26358	DNMT1	Q13131	PRKAA1	T328	T333M	333	Missense	distal	5	no	59.040	58.850	EPSD	CCLE	56.683	Down-regulation
CAMK_CAMKL_AMPK_PRKAA1_ST	P26358	DNMT1	Q13131	PRKAA1	T333	K335R	335	Missense	proximal	2	no	62.772	62.656	EPSD	CCLE	56.683	Down-regulation
CAMK_CAMKL_AMPK_PRKAA1_ST	P26358	DNMT1	Q13131	PRKAA1	T333	T333M	333	Missense	central	0	yes	62.772	0.000	EPSD	CCLE	56.683	Loss
CAMK_CAMKL_AMPK_PRKAA1_ST	P26358	DNMT1	Q13131	PRKAA1	T342	K335R	335	Missense	distal	-7	no	71.964	70.361	EPSD	CCLE	56.683	Down-regulation
CAMK_CAMKL_AMPK_PRKAA1_ST	P26358	DNMT1	Q13131	PRKAA1	S878	A874T	874	Missense	distal	-4	no	57.071	56.216	EPSD	CCLE	56.683	Loss
CAMK_CAMKL_AMPK_PRKAA1_ST	P26358	DNMT1	Q13131	PRKAA1	S1447	V1444A	1444	Missense	distal	-3	no	59.007	56.565	EPSD	CCLE	56.683	Loss
CAMK_CAMKL_AMPK_PRKAA1_ST	Q00613	HSF1	Q13131	PRKAA1	S244	P243L	243	Missense	proximal	-1	no	59.384	59.455	EPSD	CCLE	56.683	Up-regulation
CAMK_CAMKL_AMPK_PRKAA1_ST	Q00613	HSF1	Q13131	PRKAA1	S248	P243L	243	Missense	distal	-5	no	58.601	63.341	EPSD	CCLE	56.683	Up-regulation
CAMK_CAMKL_AMPK_PRKAA1_ST	Q00613	HSF1	Q13131	PRKAA1	S290	R287M	287	Missense	distal	-3	no	68.858	55.975	EPSD	CCLE	56.683	Loss
CAMK_CAMKL_AMPK_PRKAA1_ST	Q16875	PFKFB3	Q13131	PRKAA1	S211	D207G	207	Missense	distal	-4	no	63.029	59.515	EPSD	CCLE	56.683	Down-regulation
CAMK_CAMKL_AMPK_PRKAA1_ST	Q9P2M7	CGN	Q13131	PRKAA1	S43	R41C	41	Missense	proximal	-2	no	56.945	49.834	EPSD	CCLE	56.683	Loss
CAMK_CAMKL_AMPK_PRKAA1_ST	Q8IXJ6	SIRT2	Q13131	PRKAA1	S100	S100F	100	Missense	central	0	yes	56.799	0.000	EPSD	CCLE	56.683	Loss
CAMK_CAMKL_AMPK_PRKAA1_ST	Q8IXJ6	SIRT2	Q13131	PRKAA1	S100	P94T	94	Missense	distal	-6	no	56.799	56.915	EPSD	CCLE	56.683	Up-regulation
CAMK_CAMKL_AMPK_PRKAA1_ST	Q8IXJ6	SIRT2	Q13131	PRKAA1	T101	S100F	100	Missense	proximal	-1	no	58.596	58.550	PhosphoSitePlus	CCLE	56.683	Down-regulation
CAMK_CAMKL_AMPK_PRKAA1_ST	Q8IXJ6	SIRT2	Q13131	PRKAA1	T101	P94T	94	Missense	distal	-7	no	58.596	59.010	PhosphoSitePlus	CCLE	56.683	Up-regulation
CAMK_CAMKL_AMPK_PRKAA1_ST	Q14247	CTTN	Q13131	PRKAA1	S113	S106L	106	Missense	distal	-7	no	59.382	56.954	EPSD	CCLE	56.683	Down-regulation
CAMK_CAMKL_AMPK_PRKAA1_ST	Q14247	CTTN	Q13131	PRKAA1	S282	G286E	286	Missense	distal	4	no	65.321	61.763	EPSD	CCLE	56.683	Down-regulation
CAMK_CAMKL_AMPK_PRKAA1_ST	P15056	BRAF	Q13131	PRKAA1	S430	R435S	435	Missense	distal	5	no	63.157	63.122	EPSD	CCLE	56.683	Down-regulation
CAMK_CAMKL_AMPK_PRKAA1_ST	P15056	BRAF	Q13131	PRKAA1	T440	R435S	435	Missense	distal	-5	no	58.124	55.119	EPSD	CCLE	56.683	Loss
CAMK_CAMKL_AMPK_PRKAA1_ST	P15056	BRAF	Q13131	PRKAA1	S446	E451K	451	Missense	distal	5	no	72.355	72.377	EPSD	CCLE	56.683	Up-regulation
CAMK_CAMKL_AMPK_PRKAA1_ST	P15056	BRAF	Q13131	PRKAA1	S447	E451K	451	Missense	distal	4	no	63.427	69.184	EPSD	CCLE	56.683	Up-regulation
CAMK_CAMKL_AMPK_PRKAA1_ST	P15056	BRAF	Q13131	PRKAA1	S729	A728V	728	Missense	proximal	-1	no	73.936	73.845	PhosphoSitePlus	CCLE	56.683	Down-regulation
CAMK_CAMKL_AMPK_PRKAA1_ST	Q12778	FOXO1	Q13131	PRKAA1	S319	S325T	325	Missense	distal	6	no	64.829	64.764	EPSD	CCLE	56.683	Down-regulation
CAMK_CAMKL_AMPK_PRKAA1_ST	Q12778	FOXO1	Q13131	PRKAA1	S329	S325T	325	Missense	distal	-4	no	59.724	58.468	EPSD	CCLE	56.683	Down-regulation
CAMK_CAMKL_AMPK_PRKAA1_ST	Q9NR19	ACSS2	Q13131	PRKAA1	S30	R27Q	27	Missense	distal	-3	no	60.254	52.310	EPSD	CCLE	56.683	Loss
CAMK_CAMKL_AMPK_PRKAA1_ST	Q9NR19	ACSS2	Q13131	PRKAA1	S43	Y47N	47	Missense	distal	4	no	61.788	62.540	EPSD	CCLE	56.683	Up-regulation
CAMK_CAMKL_AMPK_PRKAA1_ST	O00763	ACACB	Q13131	PRKAA1	S469	R465W	465	Missense	distal	-4	no	65.316	56.653	EPSD	CCLE	56.683	Loss
CAMK_CAMKL_AMPK_PRKAA1_ST	O00763	ACACB	Q13131	PRKAA1	S469	L476I	476	Missense	distal	7	no	65.316	64.182	EPSD	CCLE	56.683	Down-regulation
CAMK_CAMKL_AMPK_PRKAA1_ST	O00763	ACACB	Q13131	PRKAA1	S1081	P1080S	1080	Missense	proximal	-1	no	57.172	57.217	EPSD	CCLE	56.683	Up-regulation
CAMK_CAMKL_AMPK_PRKAA1_ST	O00763	ACACB	Q13131	PRKAA1	S1340	M1335I	1335	Missense	distal	-5	no	59.875	60.621	EPSD	CCLE	56.683	Up-regulation
CAMK_CAMKL_AMPK_PRKAA1_ST	Q13501	SQSTM1	Q13131	PRKAA1	S284	K281R	281	Missense	distal	-3	no	63.501	68.142	EPSD	CCLE	56.683	Up-regulation
CMGC_CDK_CRK7_CDK12_ST	P24928	POLR2A	Q9NYV4	CDK12	S27	E30K	30	Missense	distal	3	no	3.928	3.927	EPSD	CCLE	0.929	Down-regulation
CMGC_CDK_CRK7_CDK12_ST	P24928	POLR2A	Q9NYV4	CDK12	T1568	P1567L	1567	Missense	proximal	-1	no	5.189	5.295	EPSD	CCLE	0.929	Up-regulation
CMGC_CDK_CRK7_CDK12_ST	P24928	POLR2A	Q9NYV4	CDK12	S1571	P1567L	1567	Missense	distal	-4	no	5.658	4.768	EPSD	CCLE	0.929	Down-regulation
CMGC_CDK_CRK7_CDK12_ST	P24928	POLR2A	Q9NYV4	CDK12	S1574	P1567L	1567	Missense	distal	-7	no	4.953	4.945	EPSD	CCLE	0.929	Down-regulation
CMGC_CDK_CRK7_CDK12_ST	P24928	POLR2A	Q9NYV4	CDK12	S1616	S1616Y	1616	Missense	central	0	yes	4.346	0.000	PhosphoSitePlus;EPSD	CCLE	0.929	Loss
CMGC_CDK_CRK7_CDK12_ST	P24928	POLR2A	Q9NYV4	CDK12	S1619	S1616Y	1616	Missense	distal	-3	no	3.907	3.880	EPSD;PhosphoSitePlus	CCLE	0.929	Down-regulation
CMGC_CDK_CRK7_CDK12_ST	P24928	POLR2A	Q9NYV4	CDK12	S1621	S1616Y	1616	Missense	distal	-5	no	1.088	1.072	EPSD	CCLE	0.929	Down-regulation
CMGC_CDK_CRK7_CDK12_ST	P24928	POLR2A	Q9NYV4	CDK12	S1654	T1660P	1660	Missense	distal	6	no	4.333	4.324	EPSD	CCLE	0.929	Down-regulation
CMGC_CDK_CRK7_CDK12_ST	P24928	POLR2A	Q9NYV4	CDK12	S1656	T1660P	1660	Missense	distal	4	no	0.759	1.264	EPSD	CCLE	0.929	Gain
CMGC_CDK_CRK7_CDK12_ST	P24928	POLR2A	Q9NYV4	CDK12	S1661	T1660P	1660	Missense	proximal	-1	no	4.328	4.259	EPSD	CCLE	0.929	Down-regulation
CMGC_CDK_CRK7_CDK12_ST	P24928	POLR2A	Q9NYV4	CDK12	S1710	Y1713S	1713	Missense	distal	3	no	4.368	4.380	EPSD	CCLE	0.929	Up-regulation
CMGC_CDK_CRK7_CDK12_ST	P24928	POLR2A	Q9NYV4	CDK12	S1717	Y1713S	1713	Missense	distal	-4	no	4.368	4.465	EPSD	CCLE	0.929	Up-regulation
CMGC_CDK_CRK7_CDK12_ST	P24928	POLR2A	Q9NYV4	CDK12	S1766	Y1762H	1762	Missense	distal	-4	no	3.736	3.761	EPSD	CCLE	0.929	Up-regulation
CMGC_CDK_CRK7_CDK12_ST	P24928	POLR2A	Q9NYV4	CDK12	T1854	K1859R	1859	Missense	distal	5	no	4.352	4.350	EPSD	CCLE	0.929	Down-regulation
CMGC_CDK_CRK7_CDK12_ST	P24928	POLR2A	Q9NYV4	CDK12	S1857	K1859R	1859	Missense	proximal	2	no	4.546	4.548	EPSD	CCLE	0.929	Up-regulation
CMGC_CDK_CRK7_CDK12_ST	P24928	POLR2A	Q9NYV4	CDK12	S1861	K1859R	1859	Missense	proximal	-2	no	4.330	4.345	EPSD	CCLE	0.929	Up-regulation
CMGC_CDK_CRK7_CDK12_ST	P24928	POLR2A	Q9NYV4	CDK12	S1864	K1859R	1859	Missense	distal	-5	no	3.958	3.962	EPSD	CCLE	0.929	Up-regulation
CMGC_CDK_CRK7_CDK12_ST	P24928	POLR2A	Q9NYV4	CDK12	S1889	T1894S	1894	Missense	distal	5	no	4.401	4.433	EPSD	CCLE	0.929	Up-regulation
CMGC_CDK_CRK7_CDK12_ST	P24928	POLR2A	Q9NYV4	CDK12	S1892	T1894S	1894	Missense	proximal	2	no	4.097	4.145	EPSD	CCLE	0.929	Up-regulation
CMGC_CDK_CRK7_CDK12_ST	P24928	POLR2A	Q9NYV4	CDK12	S1896	T1894S	1894	Missense	proximal	-2	no	4.174	4.150	EPSD	CCLE	0.929	Down-regulation
CMGC_CDK_CRK7_CDK12_ST	P24928	POLR2A	Q9NYV4	CDK12	S1899	T1894S	1894	Missense	distal	-5	no	4.022	4.034	EPSD	CCLE	0.929	Up-regulation
CMGC_CDK_CRK7_CDK12_ST	P24928	POLR2A	Q9NYV4	CDK12	S1899	P1904S	1904	Missense	distal	5	no	4.022	4.065	EPSD	CCLE	0.929	Up-regulation
CMGC_CDK_CRK7_CDK12_ST	P24928	POLR2A	Q9NYV4	CDK12	T1903	P1904S	1904	Missense	proximal	1	no	4.623	0.354	EPSD	CCLE	0.929	Loss
CMGC_CDK_CRK7_CDK12_ST	P24928	POLR2A	Q9NYV4	CDK12	S1906	P1904S	1904	Missense	proximal	-2	no	4.088	4.103	EPSD	CCLE	0.929	Up-regulation
CMGC_CDK_CRK7_CDK12_ST	P24928	POLR2A	Q9NYV4	CDK12	S1910	P1904S	1904	Missense	distal	-6	no	3.890	3.867	EPSD	CCLE	0.929	Down-regulation
CMGC_CDK_CRK7_CDK12_ST	P24928	POLR2A	Q9NYV4	CDK12	S1910	P1914L	1914	Missense	distal	4	no	3.890	3.149	EPSD	CCLE	0.929	Down-regulation
CMGC_CDK_CRK7_CDK12_ST	P24928	POLR2A	Q9NYV4	CDK12	S1913	P1914L	1914	Missense	proximal	1	no	3.778	-1.102	EPSD	CCLE	0.929	Loss
CMGC_CDK_CRK7_CDK12_ST	P24928	POLR2A	Q9NYV4	CDK12	S1917	P1914L	1914	Missense	distal	-3	no	4.181	4.233	EPSD	CCLE	0.929	Up-regulation
CMGC_CDK_CRK7_CDK12_ST	P24928	POLR2A	Q9NYV4	CDK12	S1920	P1914L	1914	Missense	distal	-6	no	4.129	4.095	EPSD	CCLE	0.929	Down-regulation
CMGC_CDK_CRK7_CDK12_ST	P24928	POLR2A	Q9NYV4	CDK12	S1934	S1941F	1941	Missense	distal	7	no	4.022	4.005	EPSD	CCLE	0.929	Down-regulation
CMGC_CDK_CRK7_CDK12_ST	P24928	POLR2A	Q9NYV4	CDK12	S1941	S1941F	1941	Missense	central	0	yes	4.371	0.000	EPSD	CCLE	0.929	Loss
CMGC_CDK_CRK7_CDK12_ST	P24928	POLR2A	Q9NYV4	CDK12	S1941	S1944Y	1944	Missense	distal	3	no	4.371	4.359	EPSD	CCLE	0.929	Down-regulation
CMGC_CDK_CRK7_CDK12_ST	P24928	POLR2A	Q9NYV4	CDK12	S1944	S1941F	1941	Missense	distal	-3	no	4.099	4.057	EPSD	CCLE	0.929	Down-regulation
CMGC_CDK_CRK7_CDK12_ST	P24928	POLR2A	Q9NYV4	CDK12	S1944	S1944Y	1944	Missense	central	0	yes	4.099	0.000	EPSD	CCLE	0.929	Loss
CMGC_CDK_CRK7_CDK12_ST	P24928	POLR2A	Q9NYV4	CDK12	S1948	S1941F	1941	Missense	distal	-7	no	5.150	5.059	EPSD	CCLE	0.929	Down-regulation
CMGC_CDK_CRK7_CDK12_ST	P24928	POLR2A	Q9NYV4	CDK12	S1948	S1944Y	1944	Missense	distal	-4	no	5.150	5.053	EPSD	CCLE	0.929	Down-regulation
CMGC_CDK_CRK7_CDK12_ST	P24928	POLR2A	Q9NYV4	CDK12	S1948	P1952A	1952	Missense	distal	4	no	5.150	4.563	EPSD	CCLE	0.929	Down-regulation
CMGC_CDK_CRK7_CDK12_ST	P24928	POLR2A	Q9NYV4	CDK12	S1951	S1944Y	1944	Missense	distal	-7	no	4.615	4.541	EPSD	CCLE	0.929	Down-regulation
CMGC_CDK_CRK7_CDK12_ST	P24928	POLR2A	Q9NYV4	CDK12	S1951	P1952A	1952	Missense	proximal	1	no	4.615	0.366	EPSD	CCLE	0.929	Loss
CMGC_CDK_CRK7_CDK12_ST	P24928	POLR2A	Q9NYV4	CDK12	S1958	P1952A	1952	Missense	distal	-6	no	4.711	4.688	EPSD	CCLE	0.929	Down-regulation
CAMK_CAMK1_CAMK4_ST	Q9UQL6	HDAC5	Q16566	CAMK4	S16	G9R	9	Missense	distal	-7	no	10.938	13.577	EPSD	CCLE	9.847	Up-regulation
CAMK_CAMK1_CAMK4_ST	Q9UQL6	HDAC5	Q16566	CAMK4	T479	T479I	479	Missense	central	0	yes	13.294	0.000	EPSD	CCLE	9.847	Loss
CAMK_CAMK1_CAMK4_ST	Q9UQL6	HDAC5	Q16566	CAMK4	S713	R710G	710	Missense	distal	-3	no	10.541	2.404	EPSD	CCLE	9.847	Loss
CAMK_CAMK1_CAMK4_ST	Q9UQL6	HDAC5	Q16566	CAMK4	S1108	E1113Q	1113	Missense	distal	5	no	10.348	10.449	EPSD	CCLE	9.847	Up-regulation
CAMK_CAMK1_CAMK4_ST	Q9UQL6	HDAC5	Q16566	CAMK4	S1108	S1108G	1108	Missense	central	0	yes	10.348	0.000	EPSD	CCLE	9.847	Loss
CAMK_CAMK1_CAMK4_ST	P14866	HNRNPL	Q16566	CAMK4	S29	S29A	29	Missense	central	0	yes	13.658	0.000	EPSD	CCLE	9.847	Loss
CAMK_CAMK1_CAMK4_ST	P14866	HNRNPL	Q16566	CAMK4	S29	R26L	26	Missense	distal	-3	no	13.658	5.796	EPSD	CCLE	9.847	Loss
CAMK_CAMK1_CAMK4_ST	P14866	HNRNPL	Q16566	CAMK4	S29	D23E	23	Missense	distal	-6	no	13.658	13.612	EPSD	CCLE	9.847	Down-regulation
CAMK_CAMK1_CAMK4_ST	P14866	HNRNPL	Q16566	CAMK4	S180	R181H	181	Missense	proximal	1	no	10.888	10.717	EPSD	CCLE	9.847	Down-regulation
CAMK_CAMK1_CAMK4_ST	P14866	HNRNPL	Q16566	CAMK4	S188	L195P	195	Missense	distal	7	no	10.614	9.424	EPSD	CCLE	9.847	Loss
CAMK_CAMK1_CAMK4_ST	P14866	HNRNPL	Q16566	CAMK4	S188	L195F	195	Missense	distal	7	no	10.614	10.276	EPSD	CCLE	9.847	Down-regulation
CAMK_CAMK1_CAMK4_ST	P14866	HNRNPL	Q16566	CAMK4	S188	S190N	190	Missense	proximal	2	no	10.614	10.624	EPSD	CCLE	9.847	Up-regulation
CAMK_CAMK1_CAMK4_ST	P14866	HNRNPL	Q16566	CAMK4	S188	R181H	181	Missense	distal	-7	no	10.614	8.181	EPSD	CCLE	9.847	Loss
CAMK_CAMK1_CAMK4_ST	P14866	HNRNPL	Q16566	CAMK4	S381	H378R	378	Missense	distal	-3	no	2.737	10.463	EPSD	CCLE	9.847	Gain
CAMK_CAMK1_CAMK4_ST	P14866	HNRNPL	Q16566	CAMK4	S544	S551T	551	Missense	distal	7	no	16.211	14.367	PhosphoSitePlus	CCLE	9.847	Down-regulation
CAMK_CAMK1_CAMK4_ST	Q99623	PHB2	Q16566	CAMK4	S96	Q100E	100	Missense	distal	4	no	10.857	11.006	EPSD	CCLE	9.847	Up-regulation
CAMK_CAMK1_CAMK4_ST	Q04206	RELA	Q16566	CAMK4	S337	S340F	340	Missense	distal	3	no	11.395	10.918	EPSD	CCLE	9.847	Down-regulation
CAMK_CAMK1_CAMK4_ST	Q04206	RELA	Q16566	CAMK4	S338	S340F	340	Missense	proximal	2	no	12.082	12.102	EPSD	CCLE	9.847	Up-regulation
CAMK_CAMK1_CAMK4_ST	Q04206	RELA	Q16566	CAMK4	S340	S340F	340	Missense	central	0	yes	11.357	0.000	EPSD	CCLE	9.847	Loss
CAMK_CAMK1_CAMK4_ST	Q04206	RELA	Q16566	CAMK4	S536	S535A	535	Missense	proximal	-1	no	12.028	12.138	PhosphoSitePlus	CCLE	9.847	Up-regulation
CAMK_CAMKL_AMPK_PRKAA2_ST	Q9UQL6	HDAC5	P54646	PRKAA2	S16	G9R	9	Missense	distal	-7	no	53.127	53.201	EPSD	CCLE	46.832	Up-regulation
CAMK_CAMKL_AMPK_PRKAA2_ST	Q9UQL6	HDAC5	P54646	PRKAA2	T479	T479I	479	Missense	central	0	yes	49.467	0.000	EPSD	CCLE	46.832	Loss
CAMK_CAMKL_AMPK_PRKAA2_ST	Q9UQL6	HDAC5	P54646	PRKAA2	T650	A644V	644	Missense	distal	-6	no	48.761	47.882	EPSD	CCLE	46.832	Down-regulation
CAMK_CAMKL_AMPK_PRKAA2_ST	Q13085	ACACA	P54646	PRKAA2	S344	E340D	340	Missense	distal	-4	no	45.933	47.287	EPSD	CCLE	46.832	Gain
CAMK_CAMKL_AMPK_PRKAA2_ST	Q13085	ACACA	P54646	PRKAA2	S1201	S1204C	1204	Missense	distal	3	no	67.265	62.374	EPSD	CCLE	46.832	Down-regulation
CAMK_CAMKL_AMPK_PRKAA2_ST	Q13085	ACACA	P54646	PRKAA2	S1201	S1203A	1203	Missense	proximal	2	no	67.265	65.301	EPSD	CCLE	46.832	Down-regulation
CAMK_CAMKL_AMPK_PRKAA2_ST	Q13085	ACACA	P54646	PRKAA2	S1216	S1216I	1216	Missense	central	0	yes	56.593	0.000	EPSD	CCLE	46.832	Loss
CAMK_CAMKL_AMPK_PRKAA2_ST	Q13085	ACACA	P54646	PRKAA2	S1218	S1216I	1216	Missense	proximal	-2	no	47.054	43.056	EPSD	CCLE	46.832	Loss
CAMK_CAMKL_AMPK_PRKAA2_ST	Q13085	ACACA	P54646	PRKAA2	T1480	T1480M	1480	Missense	central	0	yes	48.387	0.000	EPSD	CCLE	46.832	Loss
CAMK_CAMKL_AMPK_PRKAA2_ST	Q13085	ACACA	P54646	PRKAA2	S1908	H1907R	1907	Missense	proximal	-1	no	48.342	48.583	EPSD	CCLE	46.832	Up-regulation
CAMK_CAMKL_AMPK_PRKAA2_ST	Q13085	ACACA	P54646	PRKAA2	S1908	S1905R	1905	Missense	distal	-3	no	48.342	55.867	EPSD	CCLE	46.832	Up-regulation
CAMK_CAMKL_AMPK_PRKAA2_ST	P09874	PARP1	P54646	PRKAA2	T368	A367D	367	Missense	proximal	-1	no	47.400	46.979	EPSD	CCLE	46.832	Down-regulation
CAMK_CAMKL_AMPK_PRKAA2_ST	P09874	PARP1	P54646	PRKAA2	S372	A367D	367	Missense	distal	-5	no	49.979	41.752	EPSD	CCLE	46.832	Loss
CAMK_CAMKL_AMPK_PRKAA2_ST	P09874	PARP1	P54646	PRKAA2	T373	A367D	367	Missense	distal	-6	no	49.281	50.088	EPSD	CCLE	46.832	Up-regulation
CAMK_CAMKL_AMPK_PRKAA2_ST	O00418	EEF2K	P54646	PRKAA2	T364	S359C	359	Missense	distal	-5	no	47.763	37.013	EPSD	CCLE	46.832	Loss
CAMK_CAMKL_AMPK_PRKAA2_ST	O00418	EEF2K	P54646	PRKAA2	S398	S404N	404	Missense	distal	6	no	66.424	67.207	PhosphoSitePlus	CCLE	46.832	Up-regulation
CAMK_CAMKL_AMPK_PRKAA2_ST	P30260	CDC27	P54646	PRKAA2	S320	G325D	325	Missense	distal	5	no	61.039	61.088	EPSD	CCLE	46.832	Up-regulation
CAMK_CAMKL_AMPK_PRKAA2_ST	P30260	CDC27	P54646	PRKAA2	S320	I324M	324	Missense	distal	4	no	61.039	62.972	EPSD	CCLE	46.832	Up-regulation
CAMK_CAMKL_AMPK_PRKAA2_ST	P30260	CDC27	P54646	PRKAA2	T358	T359I	359	Missense	proximal	1	no	54.049	53.943	EPSD	CCLE	46.832	Down-regulation
CAMK_CAMKL_AMPK_PRKAA2_ST	O43524	FOXO3	P54646	PRKAA2	S438	R444C	444	Missense	distal	6	no	48.550	45.705	EPSD	CCLE	46.832	Loss
CAMK_CAMKL_AMPK_PRKAA2_ST	O43524	FOXO3	P54646	PRKAA2	S439	R444C	444	Missense	distal	5	no	54.748	54.482	EPSD	CCLE	46.832	Down-regulation
CAMK_CAMKL_AMPK_PRKAA2_ST	O43524	FOXO3	P54646	PRKAA2	S442	R444C	444	Missense	proximal	2	no	52.593	57.630	EPSD	CCLE	46.832	Up-regulation
CAMK_CAMKL_AMPK_PRKAA2_ST	O43524	FOXO3	P54646	PRKAA2	S446	R444C	444	Missense	proximal	-2	no	49.138	46.977	EPSD	CCLE	46.832	Down-regulation
CAMK_CAMKL_AMPK_PRKAA2_ST	P08151	GLI1	P54646	PRKAA2	T205	P202H	202	Missense	distal	-3	no	47.728	44.624	EPSD	CCLE	46.832	Loss
CAMK_CAMKL_AMPK_PRKAA2_ST	P08151	GLI1	P54646	PRKAA2	T205	G206C	206	Missense	proximal	1	no	47.728	47.646	EPSD	CCLE	46.832	Down-regulation
CAMK_CAMKL_AMPK_PRKAA2_ST	P08151	GLI1	P54646	PRKAA2	S408	S410F	410	Missense	proximal	2	no	68.083	53.872	PhosphoSitePlus;EPSD	CCLE	46.832	Down-regulation
CAMK_CAMKL_AMPK_PRKAA2_ST	P08151	GLI1	P54646	PRKAA2	S545	I549S	549	Missense	distal	4	no	59.044	59.877	EPSD	CCLE	46.832	Up-regulation
CAMK_CAMKL_AMPK_PRKAA2_ST	Q9BZL4	PPP1R12C	P54646	PRKAA2	T290	M286I	286	Missense	distal	-4	no	51.675	51.371	EPSD	CCLE	46.832	Down-regulation
CAMK_CAMKL_AMPK_PRKAA2_ST	Q9BZL4	PPP1R12C	P54646	PRKAA2	S452	S453F	453	Missense	proximal	1	no	70.646	70.553	PhosphoSitePlus	CCLE	46.832	Down-regulation
CAMK_CAMKL_AMPK_PRKAA2_ST	Q9BZL4	PPP1R12C	P54646	PRKAA2	S452	R449C	449	Missense	distal	-3	no	70.646	57.374	PhosphoSitePlus	CCLE	46.832	Down-regulation
CAMK_CAMKL_AMPK_PRKAA2_ST	Q9BZL4	PPP1R12C	P54646	PRKAA2	S502	E506D	506	Missense	distal	4	no	43.837	49.617	EPSD	CCLE	46.832	Gain
CAMK_CAMKL_AMPK_PRKAA2_ST	Q9BZL4	PPP1R12C	P54646	PRKAA2	S509	E506D	506	Missense	distal	-3	no	55.078	61.817	EPSD	CCLE	46.832	Up-regulation
CAMK_CAMKL_AMPK_PRKAA2_ST	Q9BZL4	PPP1R12C	P54646	PRKAA2	S559	Q561K	561	Missense	proximal	2	no	49.854	41.116	EPSD	CCLE	46.832	Loss
CAMK_CAMKL_AMPK_PRKAA2_ST	Q9BZL4	PPP1R12C	P54646	PRKAA2	T564	Q561K	561	Missense	distal	-3	no	42.766	51.581	EPSD	CCLE	46.832	Gain
CAMK_CAMKL_AMPK_PRKAA2_ST	Q9BXM7	PINK1	P54646	PRKAA2	S495	S499F	499	Missense	distal	4	no	68.340	71.858	EPSD;PhosphoSitePlus	CCLE	46.832	Up-regulation
CAMK_CAMKL_AMPK_PRKAA2_ST	Q9UQB8	BAIAP2	P54646	PRKAA2	T360	L361M	361	Missense	proximal	1	no	49.934	49.770	EPSD	CCLE	46.832	Down-regulation
CAMK_CAMKL_AMPK_PRKAA2_ST	Q9UQB8	BAIAP2	P54646	PRKAA2	S366	L361M	361	Missense	distal	-5	no	65.938	66.813	PhosphoSitePlus	CCLE	46.832	Up-regulation
CAMK_CAMKL_AMPK_PRKAA2_ST	Q13177	PAK2	P54646	PRKAA2	S507	S508N	508	Missense	proximal	1	no	58.874	58.762	EPSD	CCLE	46.832	Down-regulation
CAMK_CAMKL_AMPK_PRKAA2_ST	P05549	TFAP2A	P54646	PRKAA2	S239	P240L	240	Missense	proximal	1	no	50.389	50.507	EPSD	CCLE	46.832	Up-regulation
AGC_NDR_NDR_STK38L_ST	O60285	NUAK1	Q9Y2H1	STK38L	T356	P355A	355	Missense	proximal	-1	no	2.373	2.615	EPSD	CCLE	2.379	Gain
CK1_CK1_CK1-D_CSNK1E_ST	O15055	PER2	P49674	CSNK1E	S810	G815W	815	Missense	distal	5	no	25.780	26.297	EPSD	CCLE	22.404	Up-regulation
CK1_CK1_CK1-D_CSNK1E_ST	Q92997	DVL3	P49674	CSNK1E	S234	R228W	228	Missense	distal	-6	no	26.611	26.321	EPSD	CCLE	22.404	Down-regulation
CK1_CK1_CK1-D_CSNK1E_ST	Q92997	DVL3	P49674	CSNK1E	S234	I238L	238	Missense	distal	4	no	26.611	26.782	EPSD	CCLE	22.404	Up-regulation
CK1_CK1_CK1-D_CSNK1E_ST	Q92997	DVL3	P49674	CSNK1E	S237	I238L	238	Missense	proximal	1	no	25.798	25.175	EPSD	CCLE	22.404	Down-regulation
CK1_CK1_CK1-D_CSNK1E_ST	Q92997	DVL3	P49674	CSNK1E	S268	G266C	266	Missense	proximal	-2	no	23.063	18.091	EPSD	CCLE	22.404	Loss
CK1_CK1_CK1-D_CSNK1E_ST	Q92997	DVL3	P49674	CSNK1E	S598	G600A	600	Missense	proximal	2	no	30.566	34.519	EPSD	CCLE	22.404	Up-regulation
CK1_CK1_CK1-D_CSNK1E_ST	Q92997	DVL3	P49674	CSNK1E	S601	G600A	600	Missense	proximal	-1	no	18.203	23.058	EPSD	CCLE	22.404	Gain
CK1_CK1_CK1-D_CSNK1E_ST	Q92997	DVL3	P49674	CSNK1E	S603	G600A	600	Missense	distal	-3	no	25.535	23.747	EPSD	CCLE	22.404	Down-regulation
CK1_CK1_CK1-D_CSNK1E_ST	Q92997	DVL3	P49674	CSNK1E	S622	P627L	627	Missense	distal	5	no	23.100	24.092	EPSD	CCLE	22.404	Up-regulation
CK1_CK1_CK1-D_CSNK1E_ST	Q92997	DVL3	P49674	CSNK1E	S633	P627L	627	Missense	distal	-6	no	23.284	22.659	EPSD;PhosphoSitePlus	CCLE	22.404	Down-regulation
CK1_CK1_CK1-D_CSNK1E_ST	Q92997	DVL3	P49674	CSNK1E	S633	S636G	636	Missense	distal	3	no	23.284	20.582	EPSD;PhosphoSitePlus	CCLE	22.404	Loss
CK1_CK1_CK1-D_CSNK1E_ST	Q92997	DVL3	P49674	CSNK1E	S636	S636G	636	Missense	central	0	yes	26.308	0.000	EPSD;PhosphoSitePlus	CCLE	22.404	Loss
CK1_CK1_CK1-D_CSNK1E_ST	Q92997	DVL3	P49674	CSNK1E	S639	S636G	636	Missense	distal	-3	no	23.548	23.824	EPSD;PhosphoSitePlus	CCLE	22.404	Up-regulation
CK1_CK1_CK1-D_CSNK1E_ST	Q92997	DVL3	P49674	CSNK1E	S643	S636G	636	Missense	distal	-7	no	22.651	22.649	EPSD;PhosphoSitePlus	CCLE	22.404	Down-regulation
CK1_CK1_CK1-D_CSNK1E_ST	Q8TD43	TRPM4	P49674	CSNK1E	S255	R252C	252	Missense	distal	-3	no	22.910	21.473	EPSD	CCLE	22.404	Loss
CK1_CK1_CK1-D_CSNK1E_ST	Q8TD43	TRPM4	P49674	CSNK1E	S1098	S1103F	1103	Missense	distal	5	no	24.945	25.950	EPSD	CCLE	22.404	Up-regulation
CK1_CK1_CK1-D_CSNK1E_ST	Q9Y6Q9	NCOA3	P49674	CSNK1E	S214	P215L	215	Missense	proximal	1	no	37.141	36.786	EPSD	CCLE	22.404	Down-regulation
CK1_CK1_CK1-D_CSNK1E_ST	Q9Y6Q9	NCOA3	P49674	CSNK1E	S916	T910A	910	Missense	distal	-6	no	24.860	24.533	EPSD	CCLE	22.404	Down-regulation
CK1_CK1_CK1-D_CSNK1E_ST	P49674	CSNK1E	P49674	CSNK1E	T44	I51T	51	Missense	distal	7	no	33.821	34.014	EPSD	CCLE	22.404	Up-regulation
CK1_CK1_CK1-D_CSNK1E_ST	P49674	CSNK1E	P49674	CSNK1E	S350	T351K	351	Missense	proximal	1	no	25.032	25.121	EPSD	CCLE	22.404	Up-regulation
CK1_CK1_CK1-D_CSNK1E_ST	P49674	CSNK1E	P49674	CSNK1E	S350	S350F	350	Missense	central	0	yes	25.032	0.000	EPSD	CCLE	22.404	Loss
CK1_CK1_CK1-D_CSNK1E_ST	P49674	CSNK1E	P49674	CSNK1E	T351	T351K	351	Missense	central	0	yes	26.172	0.000	EPSD	CCLE	22.404	Loss
CK1_CK1_CK1-D_CSNK1E_ST	P49674	CSNK1E	P49674	CSNK1E	T351	S350F	350	Missense	proximal	-1	no	26.172	18.466	EPSD	CCLE	22.404	Loss
CK1_CK1_CK1-D_CSNK1E_ST	P49674	CSNK1E	P49674	CSNK1E	S354	T351K	351	Missense	distal	-3	no	23.316	23.926	EPSD	CCLE	22.404	Up-regulation
CK1_CK1_CK1-D_CSNK1E_ST	P49674	CSNK1E	P49674	CSNK1E	S354	S350F	350	Missense	distal	-4	no	23.316	18.193	EPSD	CCLE	22.404	Loss
CK1_CK1_CK1-D_CSNK1E_ST	O14641	DVL2	P49674	CSNK1E	S614	E613A	613	Missense	proximal	-1	no	20.603	23.807	EPSD	CCLE	22.404	Gain
CK1_CK1_CK1-D_CSNK1E_ST	O14641	DVL2	P49674	CSNK1E	S616	E613A	613	Missense	distal	-3	no	25.336	26.197	EPSD	CCLE	22.404	Up-regulation
CK1_CK1_CK1-D_CSNK1E_ST	O14641	DVL2	P49674	CSNK1E	S618	E613A	613	Missense	distal	-5	no	31.832	31.868	EPSD	CCLE	22.404	Up-regulation
CK1_CK1_CK1-D_CSNK1E_ST	O14641	DVL2	P49674	CSNK1E	T652	G653R	653	Missense	proximal	1	no	25.567	25.813	EPSD	CCLE	22.404	Up-regulation
CK1_CK1_CK1-D_CSNK1E_ST	Q13148	TARDBP	P49674	CSNK1E	T88	V94L	94	Missense	distal	6	no	24.176	26.218	EPSD	CCLE	22.404	Up-regulation
CK1_CK1_CK1-D_CSNK1E_ST	Q13148	TARDBP	P49674	CSNK1E	S91	V94L	94	Missense	distal	3	no	22.843	24.626	EPSD	CCLE	22.404	Up-regulation
CK1_CK1_CK1-D_CSNK1E_ST	Q13148	TARDBP	P49674	CSNK1E	S92	V94L	94	Missense	proximal	2	no	27.727	24.706	EPSD	CCLE	22.404	Down-regulation
CK1_CK1_CK1-D_CSNK1E_ST	Q13148	TARDBP	P49674	CSNK1E	S92	A99V	99	Missense	distal	7	no	27.727	28.184	EPSD	CCLE	22.404	Up-regulation
CK1_CK1_CK1-D_CSNK1E_ST	Q13148	TARDBP	P49674	CSNK1E	S389	N390S	390	Missense	proximal	1	no	25.241	25.570	EPSD	CCLE	22.404	Up-regulation
CK1_CK1_CK1-D_CSNK1E_ST	O75581	LRP6	P49674	CSNK1E	S1430	L1432M	1432	Missense	proximal	2	no	20.331	23.572	EPSD	CCLE	22.404	Gain
CK1_CK1_CK1-D_CSNK1E_ST	O75581	LRP6	P49674	CSNK1E	S1431	L1432M	1432	Missense	proximal	1	no	36.080	37.219	EPSD;PhosphoSitePlus	CCLE	22.404	Up-regulation
CK1_CK1_CK1-D_CSNK1E_ST	O75581	LRP6	P49674	CSNK1E	S1444	S1450T	1450	Missense	distal	6	no	30.982	26.397	EPSD	CCLE	22.404	Down-regulation
CK1_CK1_CK1-D_CSNK1E_ST	O75581	LRP6	P49674	CSNK1E	S1455	P1458F	1458	Missense	distal	3	no	23.599	22.053	EPSD	CCLE	22.404	Loss
CK1_CK1_CK1-D_CSNK1E_ST	O75581	LRP6	P49674	CSNK1E	S1455	S1450T	1450	Missense	distal	-5	no	23.599	22.291	EPSD	CCLE	22.404	Loss
CK1_CK1_CK1-D_CSNK1E_ST	P25054	APC	P49674	CSNK1E	S5	A2V	2	Missense	distal	-3	no	23.043	21.559	EPSD	CCLE	22.404	Loss
CK1_CK1_CK1-D_CSNK1E_ST	P25054	APC	P49674	CSNK1E	S1389	D1394H	1394	Missense	distal	5	no	25.057	25.334	EPSD	CCLE	22.404	Up-regulation
CK1_CK1_CK1-D_CSNK1E_ST	P25054	APC	P49674	CSNK1E	S1392	D1394H	1394	Missense	proximal	2	no	34.913	35.352	EPSD;PhosphoSitePlus	CCLE	22.404	Up-regulation
CK1_CK1_CK1-D_CSNK1E_ST	P25054	APC	P49674	CSNK1E	S1656	T1661K	1661	Missense	distal	5	no	34.573	35.291	EPSD	CCLE	22.404	Up-regulation
CK1_CK1_CK1-D_CSNK1E_ST	P25054	APC	P49674	CSNK1E	S2110	S2114I	2114	Missense	distal	4	no	29.100	29.074	EPSD	CCLE	22.404	Down-regulation
CK1_CK1_CK1-D_CSNK1E_ST	P25054	APC	P49674	CSNK1E	T2266	S2260N	2260	Missense	distal	-6	no	23.530	23.097	EPSD	CCLE	22.404	Down-regulation
CK1_CK1_CK1-D_CSNK1E_ST	P25054	APC	P49674	CSNK1E	S2359	S2361F	2361	Missense	proximal	2	no	22.635	21.448	EPSD	CCLE	22.404	Loss
CK1_CK1_CK1-D_CSNK1E_ST	P25054	APC	P49674	CSNK1E	S2594	S2596A	2596	Missense	proximal	2	no	22.380	25.042	EPSD	CCLE	22.404	Gain
CK1_CK1_CK1-D_CSNK1E_ST	P25054	APC	P49674	CSNK1E	T2629	T2635P	2635	Missense	distal	6	no	19.451	24.673	EPSD	CCLE	22.404	Gain
CK1_CK1_CK1-D_CSNK1E_ST	P25054	APC	P49674	CSNK1E	S2632	T2635P	2635	Missense	distal	3	no	31.939	36.096	EPSD	CCLE	22.404	Up-regulation
CK1_CK1_CK1-D_CSNK1E_ST	P25054	APC	P49674	CSNK1E	S2765	S2768R	2768	Missense	distal	3	no	33.220	31.175	EPSD	CCLE	22.404	Down-regulation
CK1_CK1_CK1-D_CSNK1E_ST	P25054	APC	P49674	CSNK1E	S2767	S2768R	2768	Missense	proximal	1	no	29.400	28.667	EPSD	CCLE	22.404	Down-regulation
CK1_CK1_CK1-D_CSNK1E_ST	P25054	APC	P49674	CSNK1E	S2768	S2768R	2768	Missense	central	0	yes	27.070	0.000	EPSD	CCLE	22.404	Loss
CK1_CK1_CK1-D_CSNK1E_ST	P25054	APC	P49674	CSNK1E	S2772	S2768R	2768	Missense	distal	-4	no	23.426	19.941	EPSD	CCLE	22.404	Loss
CK1_CK1_CK1-D_CSNK1E_ST	Q13541	EIF4EBP1	P49674	CSNK1E	S96	R99C	99	Missense	distal	3	no	33.148	26.100	EPSD	CCLE	22.404	Down-regulation
CAMK_CAMK1_CAMK1_ST	Q05469	LIPE	Q14012	CAMK1	S607	V601I	601	Missense	distal	-6	no	34.844	36.486	EPSD	CCLE	32.882	Up-regulation
CAMK_CAMK1_CAMK1_ST	Q05469	LIPE	Q14012	CAMK1	T1052	T1052A	1052	Missense	central	0	yes	35.892	0.000	EPSD	CCLE	32.882	Loss
CAMK_CAMK1_CAMK1_ST	Q9UQM7	CAMK2A	Q14012	CAMK1	S331	S331P	331	Missense	central	0	yes	40.579	0.000	EPSD	CCLE	32.882	Loss
CAMK_CAMK1_CAMK1_ST	Q9UKV0	HDAC9	Q14012	CAMK1	T141	A139T	139	Missense	proximal	-2	no	36.021	39.387	EPSD	CCLE	32.882	Up-regulation
CAMK_CAMK1_CAMK1_ST	Q9UKV0	HDAC9	Q14012	CAMK1	S240	A235T	235	Missense	distal	-5	no	36.517	41.544	EPSD	CCLE	32.882	Up-regulation
CAMK_CAMK1_CAMK1_ST	Q9UKV0	HDAC9	Q14012	CAMK1	S607	R608S	608	Missense	proximal	1	no	38.783	39.565	EPSD	CCLE	32.882	Up-regulation
CAMK_CAMK1_CAMK1_ST	Q9UKV0	HDAC9	Q14012	CAMK1	S611	R608S	608	Missense	distal	-3	no	38.514	17.607	EPSD	CCLE	32.882	Loss
TK_Src_SrcA_YES1_Y	P09917	ALOX5	P07947	YES1	Y23	L26P	26	Missense	distal	3	no	24.000	26.106	PhosphoSitePlus;EPSD	CCLE	16.372	Up-regulation
TK_Src_SrcA_YES1_Y	P04626	ERBB2	P07947	YES1	Y1248	D1252N	1252	Missense	distal	4	no	16.654	16.827	EPSD	CCLE	16.372	Up-regulation
TK_Src_SrcA_YES1_Y	P46527	CDKN1B	P07947	YES1	Y88	F87L	87	Missense	proximal	-1	no	30.194	30.271	EPSD;PhosphoSitePlus	CCLE	16.372	Up-regulation
TK_Src_SrcA_YES1_Y	P46527	CDKN1B	P07947	YES1	Y88	Y89C	89	Missense	proximal	1	no	30.194	28.285	EPSD;PhosphoSitePlus	CCLE	16.372	Down-regulation
TK_Src_SrcA_YES1_Y	P46527	CDKN1B	P07947	YES1	Y89	F87L	87	Missense	proximal	-2	no	28.772	28.752	PhosphoSitePlus;EPSD	CCLE	16.372	Down-regulation
TK_Src_SrcA_YES1_Y	P46527	CDKN1B	P07947	YES1	Y89	Y89C	89	Missense	central	0	yes	28.772	0.000	PhosphoSitePlus;EPSD	CCLE	16.372	Loss
TK_Src_SrcA_YES1_Y	P14921	ETS1	P07947	YES1	Y258	I255V	255	Missense	distal	-3	no	9.724	17.032	EPSD	CCLE	16.372	Gain
TK_Src_SrcA_YES1_Y	P14921	ETS1	P07947	YES1	Y283	S285R	285	Missense	proximal	2	no	22.413	22.205	PhosphoSitePlus	CCLE	16.372	Down-regulation
TK_Src_SrcA_YES1_Y	Q16543	CDC37	P07947	YES1	Y298	E296K	296	Missense	proximal	-2	no	29.701	29.645	PhosphoSitePlus	CCLE	16.372	Down-regulation
TK_Src_SrcA_YES1_Y	P11802	CDK4	P07947	YES1	Y17	E11G	11	Missense	distal	-6	no	28.759	29.351	PhosphoSitePlus	CCLE	16.372	Up-regulation
TK_Src_SrcA_YES1_Y	P11802	CDK4	P07947	YES1	Y165	A170T	170	Missense	distal	5	no	17.679	16.259	EPSD	CCLE	16.372	Loss
Other_IKK_TBK1_ST	Q13501	SQSTM1	Q9UHD2	TBK1	S170	P171L	171	Missense	proximal	1	no	141.130	148.199	EPSD	CCLE	145.681	Gain
Other_IKK_TBK1_ST	Q13501	SQSTM1	Q9UHD2	TBK1	S275	K281R	281	Missense	distal	6	no	154.122	153.882	EPSD	CCLE	145.681	Down-regulation
Other_IKK_TBK1_ST	Q13501	SQSTM1	Q9UHD2	TBK1	S276	K281R	281	Missense	distal	5	no	158.047	160.142	EPSD	CCLE	145.681	Up-regulation
Other_IKK_TBK1_ST	Q13501	SQSTM1	Q9UHD2	TBK1	S287	K281R	281	Missense	distal	-6	no	140.969	150.101	EPSD	CCLE	145.681	Gain
Other_IKK_TBK1_ST	Q13501	SQSTM1	Q9UHD2	TBK1	S355	S361F	361	Missense	distal	6	no	155.173	143.840	EPSD	CCLE	145.681	Loss
Other_IKK_TBK1_ST	Q13501	SQSTM1	Q9UHD2	TBK1	S365	S361F	361	Missense	distal	-4	no	156.094	155.137	EPSD	CCLE	145.681	Down-regulation
Other_IKK_TBK1_ST	Q13501	SQSTM1	Q9UHD2	TBK1	S366	S361F	361	Missense	distal	-5	no	155.023	153.811	EPSD	CCLE	145.681	Down-regulation
Other_IKK_TBK1_ST	Q96CV9	OPTN	Q9UHD2	TBK1	S216	R217I	217	Missense	proximal	1	no	144.488	149.655	EPSD	CCLE	145.681	Gain
Other_IKK_TBK1_ST	Q96CV9	OPTN	Q9UHD2	TBK1	S519	T525A	525	Missense	distal	6	no	150.700	156.240	EPSD	CCLE	145.681	Up-regulation
Other_IKK_TBK1_ST	P23443	RPS6KB1	Q9UHD2	TBK1	S447	G454V	454	Missense	distal	7	no	187.584	187.583	PhosphoSitePlus;EPSD	CCLE	145.681	Down-regulation
Other_IKK_TBK1_ST	Q8TEV9	SMCR8	Q9UHD2	TBK1	S465	M462I	462	Missense	distal	-3	no	149.808	148.149	EPSD	CCLE	145.681	Down-regulation
Other_IKK_TBK1_ST	Q8TEV9	SMCR8	Q9UHD2	TBK1	S467	M462I	462	Missense	distal	-5	no	160.327	159.653	EPSD	CCLE	145.681	Down-regulation
Other_IKK_TBK1_ST	Q8TEV9	SMCR8	Q9UHD2	TBK1	S516	C523Y	523	Missense	distal	7	no	159.533	159.485	EPSD	CCLE	145.681	Down-regulation
Other_IKK_TBK1_ST	Q8TEV9	SMCR8	Q9UHD2	TBK1	T522	C523Y	523	Missense	proximal	1	no	120.433	168.308	EPSD	CCLE	145.681	Gain
Other_IKK_TBK1_ST	Q8TEV9	SMCR8	Q9UHD2	TBK1	S667	S660N	660	Missense	distal	-7	no	146.772	145.813	EPSD	CCLE	145.681	Down-regulation
Other_IKK_TBK1_ST	Q8TEV9	SMCR8	Q9UHD2	TBK1	S932	P931S	931	Missense	proximal	-1	no	165.178	164.775	EPSD	CCLE	145.681	Down-regulation
Other_IKK_TBK1_ST	Q14653	IRF3	Q9UHD2	TBK1	S385	A384D	384	Missense	proximal	-1	no	181.022	180.568	EPSD;PhosphoSitePlus	CCLE	145.681	Down-regulation
Other_IKK_TBK1_ST	Q14653	IRF3	Q9UHD2	TBK1	S386	A384D	384	Missense	proximal	-2	no	184.690	185.504	EPSD;PhosphoSitePlus	CCLE	145.681	Up-regulation
Other_IKK_TBK1_ST	Q14653	IRF3	Q9UHD2	TBK1	T390	A384D	384	Missense	distal	-6	no	156.230	161.018	EPSD	CCLE	145.681	Up-regulation
Other_IKK_TBK1_ST	Q01094	E2F1	Q9UHD2	TBK1	S382	E385D	385	Missense	distal	3	no	150.970	151.696	EPSD	CCLE	145.681	Up-regulation
Other_IKK_TBK1_ST	Q92985	IRF7	Q9UHD2	TBK1	S471	R467C	467	Missense	distal	-4	no	179.793	180.005	EPSD;PhosphoSitePlus	CCLE	145.681	Up-regulation
Other_IKK_TBK1_ST	Q92985	IRF7	Q9UHD2	TBK1	S472	R467C	467	Missense	distal	-5	no	185.384	184.326	EPSD;PhosphoSitePlus	CCLE	145.681	Down-regulation
Other_IKK_TBK1_ST	Q92985	IRF7	Q9UHD2	TBK1	S487	I492F	492	Missense	distal	5	no	149.138	147.902	EPSD	CCLE	145.681	Down-regulation
Other_IKK_TBK1_ST	Q9BRV8	SIKE1	Q9UHD2	TBK1	S59	D57N	57	Missense	proximal	-2	no	164.059	162.814	EPSD	CCLE	145.681	Down-regulation
Other_IKK_TBK1_ST	Q9BRV8	SIKE1	Q9UHD2	TBK1	S185	S190F	190	Missense	distal	5	no	183.321	179.741	PhosphoSitePlus;EPSD	CCLE	145.681	Down-regulation
Other_IKK_TBK1_ST	Q9BRV8	SIKE1	Q9UHD2	TBK1	S185	R181Q	181	Missense	distal	-4	no	183.321	184.334	PhosphoSitePlus;EPSD	CCLE	145.681	Up-regulation
Other_IKK_TBK1_ST	Q9BRV8	SIKE1	Q9UHD2	TBK1	S187	S190F	190	Missense	distal	3	no	187.867	189.587	EPSD;PhosphoSitePlus	CCLE	145.681	Up-regulation
Other_IKK_TBK1_ST	Q9BRV8	SIKE1	Q9UHD2	TBK1	S187	R181Q	181	Missense	distal	-6	no	187.867	194.014	EPSD;PhosphoSitePlus	CCLE	145.681	Up-regulation
Other_IKK_TBK1_ST	Q9BRV8	SIKE1	Q9UHD2	TBK1	S188	S190F	190	Missense	proximal	2	no	177.364	167.118	EPSD;PhosphoSitePlus	CCLE	145.681	Down-regulation
Other_IKK_TBK1_ST	Q9BRV8	SIKE1	Q9UHD2	TBK1	S188	R181Q	181	Missense	distal	-7	no	177.364	178.031	EPSD;PhosphoSitePlus	CCLE	145.681	Up-regulation
Other_IKK_TBK1_ST	Q9BRV8	SIKE1	Q9UHD2	TBK1	S190	S190F	190	Missense	central	0	yes	200.159	0.000	EPSD;PhosphoSitePlus	CCLE	145.681	Loss
Other_IKK_TBK1_ST	Q9BRV8	SIKE1	Q9UHD2	TBK1	S198	Q204K	204	Missense	distal	6	no	176.993	174.789	EPSD;PhosphoSitePlus	CCLE	145.681	Down-regulation
Other_IKK_TBK1_ST	Q9BRV8	SIKE1	Q9UHD2	TBK1	S198	M199I	199	Missense	proximal	1	no	176.993	180.393	EPSD;PhosphoSitePlus	CCLE	145.681	Up-regulation
Other_IKK_TBK1_ST	P31749	AKT1	Q9UHD2	TBK1	S457	V461A	461	Missense	distal	4	no	151.106	150.336	EPSD	CCLE	145.681	Down-regulation
Other_IKK_TBK1_ST	P31749	AKT1	Q9UHD2	TBK1	S457	M458T	458	Missense	proximal	1	no	151.106	109.238	EPSD	CCLE	145.681	Loss
Other_IKK_TBK1_ST	Q9UHD2	TBK1	Q9UHD2	TBK1	S151	V152L	152	Missense	proximal	1	no	127.847	151.810	EPSD	CCLE	145.681	Gain
Other_IKK_TBK1_ST	Q9UHD2	TBK1	Q9UHD2	TBK1	T333	I334L	334	Missense	proximal	1	no	161.014	163.041	EPSD	CCLE	145.681	Up-regulation
Other_IKK_TBK1_ST	Q13568	IRF5	Q9UHD2	TBK1	S156	L157P	157	Missense	proximal	1	no	160.190	153.121	EPSD	CCLE	145.681	Down-regulation
Other_IKK_TBK1_ST	Q13568	IRF5	Q9UHD2	TBK1	S158	L157P	157	Missense	proximal	-1	no	182.527	182.931	EPSD;PhosphoSitePlus	CCLE	145.681	Up-regulation
Other_IKK_TBK1_ST	Q04206	RELA	Q9UHD2	TBK1	S536	S535A	535	Missense	proximal	-1	no	167.526	167.927	PhosphoSitePlus	CCLE	145.681	Up-regulation
Other_IKK_TBK1_ST	Q7Z434	MAVS	Q9UHD2	TBK1	S217	S217C	217	Missense	central	0	yes	151.239	0.000	EPSD	CCLE	145.681	Loss
Other_IKK_TBK1_ST	Q7Z434	MAVS	Q9UHD2	TBK1	S401	T398I	398	Missense	distal	-3	no	162.766	159.978	EPSD	CCLE	145.681	Down-regulation
Other_IKK_TBK1_ST	P03372	ESR1	Q9UHD2	TBK1	S104	F97S	97	Missense	distal	-7	no	154.752	156.689	EPSD	CCLE	145.681	Up-regulation
CAMK_PKD_PRKD3_ST	Q9UQL6	HDAC5	O94806	PRKD3	S7	G9R	9	Missense	proximal	2	no	2.665	2.650	EPSD	CCLE	1.136	Down-regulation
CAMK_PKD_PRKD3_ST	Q9UQL6	HDAC5	O94806	PRKD3	S1108	S1108G	1108	Missense	central	0	yes	1.221	0.000	EPSD	CCLE	1.136	Loss
CAMK_PKD_PRKD3_ST	Q15139	PRKD1	O94806	PRKD3	S549	V550M	550	Missense	proximal	1	no	2.374	2.381	EPSD	CCLE	1.136	Up-regulation
CAMK_PKD_PRKD3_ST	Q9Y2X7	GIT1	O94806	PRKD3	S585	G591S	591	Missense	distal	6	no	1.980	1.989	EPSD	CCLE	1.136	Up-regulation
AGC_PKC_PKCa_PRKCB_ST	P10636	MAPT	P05771-2	PRKCB	S171	P170F	170	Missense	proximal	-1	no	2.924	3.133	EPSD	CCLE	0.942	Up-regulation
AGC_PKC_PKCa_PRKCB_ST	P10636	MAPT	P05771-2	PRKCB	S171	G174A	174	Missense	distal	3	no	2.924	2.973	EPSD	CCLE	0.942	Up-regulation
AGC_PKC_PKCa_PRKCB_ST	P10636	MAPT	P05771-2	PRKCB	S214	D221Y	221	Missense	distal	7	no	1.656	1.696	EPSD	CCLE	0.942	Up-regulation
AGC_PKC_PKCa_PRKCB_ST	P10636	MAPT	P05771-2	PRKCB	S400	K405R	405	Missense	distal	5	no	5.186	5.125	EPSD	CCLE	0.942	Down-regulation
AGC_PKC_PKCa_PRKCB_ST	P10636	MAPT	P05771-2	PRKCB	T403	K405R	405	Missense	proximal	2	no	1.137	2.760	EPSD	CCLE	0.942	Up-regulation
AGC_PKC_PKCa_PRKCB_ST	P10636	MAPT	P05771-2	PRKCB	S438	V442I	442	Missense	distal	4	no	1.209	1.269	EPSD	CCLE	0.942	Up-regulation
AGC_PKC_PKCa_PRKCB_ST	P10636	MAPT	P05771-2	PRKCB	S525	G518S	518	Missense	distal	-7	no	1.150	1.069	EPSD	CCLE	0.942	Down-regulation
AGC_PKC_PKCa_PRKCB_ST	P10636	MAPT	P05771-2	PRKCB	S525	R526L	526	Missense	proximal	1	no	1.150	0.465	EPSD	CCLE	0.942	Loss
AGC_PKC_PKCa_PRKCB_ST	P10636	MAPT	P05771-2	PRKCB	S531	R526L	526	Missense	distal	-5	no	1.751	1.496	EPSD	CCLE	0.942	Down-regulation
AGC_PKC_PKCa_PRKCB_ST	P10636	MAPT	P05771-2	PRKCB	S555	R559H	559	Missense	distal	4	no	2.171	1.349	EPSD	CCLE	0.942	Down-regulation
AGC_PKC_PKCa_PRKCB_ST	P10636	MAPT	P05771-2	PRKCB	S633	D631E	631	Missense	proximal	-2	no	1.139	2.051	EPSD	CCLE	0.942	Up-regulation
AGC_PKC_PKCa_PRKCB_ST	P10636	MAPT	P05771-2	PRKCB	S637	D631E	631	Missense	distal	-6	no	4.072	4.169	EPSD	CCLE	0.942	Up-regulation
AGC_PKC_PKCa_PRKCB_ST	P10636	MAPT	P05771-2	PRKCB	S721	S717C	717	Missense	distal	-4	no	2.050	2.232	EPSD	CCLE	0.942	Up-regulation
AGC_PKC_PKCa_PRKCB_ST	P10636	MAPT	P05771-2	PRKCB	S721	S721C	721	Missense	central	0	yes	2.050	0.000	EPSD	CCLE	0.942	Loss
AGC_PKC_PKCa_PRKCB_ST	P10636	MAPT	P05771-2	PRKCB	S721	H724R	724	Missense	distal	3	no	2.050	2.855	EPSD	CCLE	0.942	Up-regulation
AGC_PKC_PKCa_PRKCB_ST	P05107	ITGB2	P05771-2	PRKCB	T118	V117M	117	Missense	proximal	-1	no	4.279	4.339	EPSD	CCLE	0.942	Up-regulation
AGC_PKC_PKCa_PRKCB_ST	P98082	DAB2	P05771-2	PRKCB	S390	P397S	397	Missense	distal	7	no	3.515	3.422	EPSD	CCLE	0.942	Down-regulation
AGC_PKC_PKCa_PRKCB_ST	P98082	DAB2	P05771-2	PRKCB	S390	N387S	387	Missense	distal	-3	no	3.515	3.049	EPSD	CCLE	0.942	Down-regulation
AGC_PKC_PKCa_PRKCB_ST	P98082	DAB2	P05771-2	PRKCB	S419	Q421R	421	Missense	proximal	2	no	-4.573	1.976	EPSD	CCLE	0.942	Gain
AGC_PKC_PKCa_PRKCB_ST	P05771	PRKCB	P05771-2	PRKCB	S111	I106F	106	Missense	distal	-5	no	2.681	2.635	EPSD	CCLE	0.942	Down-regulation
AGC_PKC_PKCa_PRKCB_ST	P05771	PRKCB	P05771-2	PRKCB	T250	W247R	247	Missense	distal	-3	no	-3.667	1.825	EPSD	CCLE	0.942	Gain
AGC_PKC_PKCa_PRKCB_ST	P53004	BLVRA	P05771-2	PRKCB	S21	R18Q	18	Missense	distal	-3	no	6.698	3.500	EPSD	CCLE	0.942	Down-regulation
AGC_PKC_PKCa_PRKCB_ST	P15336	ATF2	P05771-2	PRKCB	S314	A319D	319	Missense	distal	5	no	1.491	1.581	EPSD	CCLE	0.942	Up-regulation
AGC_PKC_PKCa_PRKCB_ST	P15336	ATF2	P05771-2	PRKCB	S314	S307L	307	Missense	distal	-7	no	1.491	1.485	EPSD	CCLE	0.942	Down-regulation
AGC_PKC_PKCa_PRKCB_ST	P49841	GSK3B	P05771-2	PRKCB	S203	K205R	205	Missense	proximal	2	no	2.951	4.575	EPSD	CCLE	0.942	Up-regulation
AGC_PKC_PKCa_PRKCB_ST	P35579	MYH9	P05771-2	PRKCB	S232	N229K	229	Missense	distal	-3	no	-0.459	2.702	EPSD	CCLE	0.942	Gain
AGC_PKC_PKCa_PRKCB_ST	P35579	MYH9	P05771-2	PRKCB	S344	Q348P	348	Missense	distal	4	no	3.033	2.770	EPSD	CCLE	0.942	Down-regulation
AGC_PKC_PKCa_PRKCB_ST	P35579	MYH9	P05771-2	PRKCB	S541	F542S	542	Missense	proximal	1	no	1.313	-0.527	EPSD	CCLE	0.942	Loss
AGC_PKC_PKCa_PRKCB_ST	P35579	MYH9	P05771-2	PRKCB	S541	P535L	535	Missense	distal	-6	no	1.313	1.328	EPSD	CCLE	0.942	Up-regulation
AGC_PKC_PKCa_PRKCB_ST	P35579	MYH9	P05771-2	PRKCB	S957	R959Q	959	Missense	proximal	2	no	4.481	-2.068	EPSD	CCLE	0.942	Loss
AGC_PKC_PKCa_PRKCB_ST	P35579	MYH9	P05771-2	PRKCB	S1398	H1401Y	1401	Missense	distal	3	no	4.442	4.468	EPSD	CCLE	0.942	Up-regulation
AGC_PKC_PKCa_PRKCB_ST	P35579	MYH9	P05771-2	PRKCB	S1869	T1870A	1870	Missense	proximal	1	no	0.650	1.096	EPSD	CCLE	0.942	Gain
AGC_PKC_PKCa_PRKCB_ST	P14598	NCF1	P05771-2	PRKCB	S320	R326H	326	Missense	distal	6	no	1.012	0.252	PhosphoSitePlus;EPSD	CCLE	0.942	Loss
AGC_PKC_PKCa_PRKCB_ST	P14598	NCF1	P05771-2	PRKCB	S328	R326H	326	Missense	proximal	-2	no	6.012	3.997	EPSD;PhosphoSitePlus	CCLE	0.942	Down-regulation
AGC_PKC_PKCa_PRKCB_ST	P14598	NCF1	P05771-2	PRKCB	T356	R354L	354	Missense	proximal	-2	no	4.947	2.427	EPSD	CCLE	0.942	Down-regulation
AGC_PKC_PKCa_PRKCB_ST	P14598	NCF1	P05771-2	PRKCB	T356	Q357H	357	Missense	proximal	1	no	4.947	3.939	EPSD	CCLE	0.942	Down-regulation
AGC_PKC_PKCa_PRKCB_ST	P14598	NCF1	P05771-2	PRKCB	S359	R354L	354	Missense	distal	-5	no	1.535	1.280	EPSD;PhosphoSitePlus	CCLE	0.942	Down-regulation
AGC_PKC_PKCa_PRKCB_ST	P14598	NCF1	P05771-2	PRKCB	S359	Q357H	357	Missense	proximal	-2	no	1.535	0.491	EPSD;PhosphoSitePlus	CCLE	0.942	Loss
AGC_PKC_PKCa_PRKCB_ST	Q14152	EIF3A	P05771-2	PRKCB	S978	F977L	977	Missense	proximal	-1	no	3.884	3.727	EPSD	CCLE	0.942	Down-regulation
AGC_PKC_PKCa_PRKCB_ST	Q14152	EIF3A	P05771-2	PRKCB	S1195	P1191S	1191	Missense	distal	-4	no	1.857	1.760	EPSD	CCLE	0.942	Down-regulation
AGC_PKC_PKCa_PRKCB_ST	P20700	LMNB1	P05771-2	PRKCB	S28	R29W	29	Missense	proximal	1	no	1.955	-0.718	EPSD	CCLE	0.942	Loss
AGC_PKC_PKCa_PRKCB_ST	P20700	LMNB1	P05771-2	PRKCB	S284	S288R	288	Missense	distal	4	no	0.375	1.392	EPSD	CCLE	0.942	Gain
AGC_PKC_PKCa_PRKCB_ST	P20700	LMNB1	P05771-2	PRKCB	S288	S288R	288	Missense	central	0	yes	3.903	0.000	EPSD	CCLE	0.942	Loss
AGC_PKC_PKCa_PRKCB_ST	P20700	LMNB1	P05771-2	PRKCB	S288	E295G	295	Missense	distal	7	no	3.903	4.071	EPSD	CCLE	0.942	Up-regulation
AGC_PKC_PKCa_PRKCB_ST	P20700	LMNB1	P05771-2	PRKCB	S302	E295G	295	Missense	distal	-7	no	2.387	2.579	EPSD	CCLE	0.942	Up-regulation
AGC_PKC_PKCa_PRKCB_ST	P20700	LMNB1	P05771-2	PRKCB	T340	R337C	337	Missense	distal	-3	no	2.010	-1.890	EPSD	CCLE	0.942	Loss
AGC_PKC_PKCa_PRKCB_ST	P20700	LMNB1	P05771-2	PRKCB	S405	R407H	407	Missense	proximal	2	no	7.169	0.808	PhosphoSitePlus;EPSD	CCLE	0.942	Loss
AGC_PKC_PKCa_PRKCB_ST	P20700	LMNB1	P05771-2	PRKCB	S408	R407H	407	Missense	proximal	-1	no	1.690	1.208	EPSD	CCLE	0.942	Down-regulation
AGC_PKC_PKCa_PRKCB_ST	P20700	LMNB1	P05771-2	PRKCB	T411	R407H	407	Missense	distal	-4	no	2.783	3.089	EPSD	CCLE	0.942	Up-regulation
AGC_PKC_PKCa_PRKCB_ST	Q5T7P8	SYT6	P05771-2	PRKCB	S148	R155L	155	Missense	distal	7	no	3.643	3.873	EPSD	CCLE	0.942	Up-regulation
AGC_PKC_PKCa_PRKCB_ST	Q5T7P8	SYT6	P05771-2	PRKCB	S148	Q146R	146	Missense	proximal	-2	no	3.643	4.615	EPSD	CCLE	0.942	Up-regulation
AGC_PKC_PKCa_PRKCB_ST	Q5T7P8	SYT6	P05771-2	PRKCB	S169	T173M	173	Missense	distal	4	no	1.291	1.351	EPSD	CCLE	0.942	Up-regulation
AGC_PKC_PKCa_PRKCB_ST	Q5T7P8	SYT6	P05771-2	PRKCB	T283	R284W	284	Missense	proximal	1	no	3.174	0.501	EPSD;PhosphoSitePlus	CCLE	0.942	Loss
AGC_PKC_PKCa_PRKCB_ST	O15350	TP73	P05771-2	PRKCB	S326	A320T	320	Missense	distal	-6	no	6.967	7.108	EPSD	CCLE	0.942	Up-regulation
AGC_PKC_PKCa_PRKCB_ST	O15350	TP73	P05771-2	PRKCB	S388	Q392R	392	Missense	distal	4	no	2.009	2.629	PhosphoSitePlus	CCLE	0.942	Up-regulation
AGC_PKC_PKCa_PRKCB_ST	O15350	TP73	P05771-2	PRKCB	S426	P425L	425	Missense	proximal	-1	no	3.051	3.102	EPSD	CCLE	0.942	Up-regulation
AGC_PKC_PKCa_PRKCB_ST	P28329	CHAT	P05771-2	PRKCB	S464	A471V	471	Missense	distal	7	no	5.753	5.698	EPSD	CCLE	0.942	Down-regulation
AGC_PKC_PKCa_PRKCB_ST	P28329	CHAT	P05771-2	PRKCB	S465	A471V	471	Missense	distal	6	no	4.475	4.550	EPSD	CCLE	0.942	Up-regulation
AGC_PKC_PKCa_PRKCB_ST	P28329	CHAT	P05771-2	PRKCB	S558	A557E	557	Missense	proximal	-1	no	6.129	6.384	EPSD	CCLE	0.942	Up-regulation
AGC_PKC_PKCa_PRKCB_ST	P28329	CHAT	P05771-2	PRKCB	S594	V591L	591	Missense	distal	-3	no	2.132	0.191	EPSD	CCLE	0.942	Loss
AGC_PKC_PKCa_PRKCB_ST	P35637	FUS	P05771-2	PRKCB	S346	A347T	347	Missense	proximal	1	no	1.509	1.063	EPSD	CCLE	0.942	Down-regulation
TK_Syk_SYK_Y	P02730	SLC4A1	P43405	SYK	Y904	D902H	902	Missense	proximal	-2	no	22.145	18.968	PhosphoSitePlus;EPSD	CCLE	13.041	Down-regulation
TK_Syk_SYK_Y	Q8IWV1	LAX1	P43405	SYK	Y373	V376M	376	Missense	distal	3	no	29.132	30.174	EPSD;PhosphoSitePlus	CCLE	13.041	Up-regulation
TK_Syk_SYK_Y	P16885	PLCG2	P43405	SYK	Y759	I765V	765	Missense	distal	6	no	16.328	16.317	PhosphoSitePlus	CCLE	13.041	Down-regulation
TK_Syk_SYK_Y	P13569	CFTR	P43405	SYK	Y512	R518G	518	Missense	distal	6	no	13.984	14.118	PhosphoSitePlus	CCLE	13.041	Up-regulation
TK_Syk_SYK_Y	Q9GZY6	LAT2	P43405	SYK	Y233	V238M	238	Missense	distal	5	no	21.413	21.475	PhosphoSitePlus;EPSD	CCLE	13.041	Up-regulation
TK_Syk_SYK_Y	Q14247	CTTN	P43405	SYK	Y289	G286E	286	Missense	distal	-3	no	12.336	14.993	EPSD	CCLE	13.041	Gain
TK_Syk_SYK_Y	P10636	MAPT	P43405	SYK	Y514	R511H	511	Missense	distal	-3	no	18.664	19.663	EPSD	CCLE	13.041	Up-regulation
TK_Syk_SYK_Y	P10636	MAPT	P43405	SYK	Y514	G518S	518	Missense	distal	4	no	18.664	18.968	EPSD	CCLE	13.041	Up-regulation
TK_Syk_SYK_Y	P10636	MAPT	P43405	SYK	Y711	G706V	706	Missense	distal	-5	no	16.864	16.562	EPSD	CCLE	13.041	Down-regulation
TK_Syk_SYK_Y	P10636	MAPT	P43405	SYK	Y711	S717C	717	Missense	distal	6	no	16.864	16.423	EPSD	CCLE	13.041	Down-regulation
TK_Syk_SYK_Y	Q13094	LCP2	P43405	SYK	Y173	M172V	172	Missense	proximal	-1	no	14.138	13.109	EPSD	CCLE	13.041	Down-regulation
TK_Syk_SYK_Y	O14986	PIP5K1B	P43405	SYK	Y105	E112Q	112	Missense	distal	7	no	16.430	15.974	PhosphoSitePlus	CCLE	13.041	Down-regulation
STE_STE20_FRAY_STK39_ST	Q13621	SLC12A1	Q9UEW8	STK39	S120	N127K	127	Missense	distal	7	no	64.347	64.361	EPSD	CCLE	61.825	Up-regulation
STE_STE20_FRAY_STK39_ST	Q13621	SLC12A1	Q9UEW8	STK39	T882	T882K	882	Missense	central	0	yes	131.807	0.000	EPSD	CCLE	61.825	Loss
STE_STE20_FRAY_STK39_ST	Q13621	SLC12A1	Q9UEW8	STK39	S885	T882K	882	Missense	distal	-3	no	62.500	65.967	EPSD	CCLE	61.825	Up-regulation
STE_STE20_FRAY_STK39_ST	Q9Y6R1	SLC4A4	Q9UEW8	STK39	S65	N72H	72	Missense	distal	7	no	113.053	113.057	PhosphoSitePlus	CCLE	61.825	Up-regulation
STE_STE20_FRAY_STK39_ST	Q9Y6R1	SLC4A4	Q9UEW8	STK39	S245	T239S	239	Missense	distal	-6	no	86.181	90.843	EPSD	CCLE	61.825	Up-regulation
STE_STE20_FRAY_STK39_ST	Q9Y666	SLC12A7	Q9UEW8	STK39	T21	E20K	20	Missense	proximal	-1	no	75.725	74.497	EPSD	CCLE	61.825	Down-regulation
STE_STE20_FRAY_STK39_ST	Q9Y666	SLC12A7	Q9UEW8	STK39	T21	G18R	18	Missense	distal	-3	no	75.725	78.406	EPSD	CCLE	61.825	Up-regulation
STE_STE20_FRAY_STK39_ST	Q9Y666	SLC12A7	Q9UEW8	STK39	T21	G17D	17	Missense	distal	-4	no	75.725	84.429	EPSD	CCLE	61.825	Up-regulation
STE_STE20_FRAY_STK39_ST	Q9Y666	SLC12A7	Q9UEW8	STK39	T958	A963T	963	Missense	distal	5	no	81.330	90.748	EPSD	CCLE	61.825	Up-regulation
STE_STE20_FRAY_STK39_ST	Q9Y666	SLC12A7	Q9UEW8	STK39	S960	A963T	963	Missense	distal	3	no	72.283	72.381	EPSD	CCLE	61.825	Up-regulation
STE_STE20_FRAY_STK39_ST	Q9Y666	SLC12A7	Q9UEW8	STK39	T962	A963T	963	Missense	proximal	1	no	71.316	80.755	EPSD	CCLE	61.825	Up-regulation
STE_STE20_FRAY_STK39_ST	Q9Y666	SLC12A7	Q9UEW8	STK39	T968	A963T	963	Missense	distal	-5	no	33.637	76.152	EPSD	CCLE	61.825	Gain
STE_STE20_FRAY_STK39_ST	Q9UHW9	SLC12A6	Q9UEW8	STK39	T54	R48Q	48	Missense	distal	-6	no	71.164	56.876	EPSD	CCLE	61.825	Loss
STE_STE20_FRAY_STK39_ST	Q9UHW9	SLC12A6	Q9UEW8	STK39	T72	D76E	76	Missense	distal	4	no	81.995	72.813	EPSD	CCLE	61.825	Down-regulation
STE_STE20_FRAY_STK39_ST	Q9UHW9	SLC12A6	Q9UEW8	STK39	S96	N95S	95	Missense	proximal	-1	no	125.264	119.481	EPSD;PhosphoSitePlus	CCLE	61.825	Down-regulation
STE_STE20_FRAY_STK39_ST	Q9UHW9	SLC12A6	Q9UEW8	STK39	T1028	R1021Q	1021	Missense	distal	-7	no	102.031	102.320	EPSD	CCLE	61.825	Up-regulation
STE_STE20_FRAY_STK39_ST	Q9UHW9	SLC12A6	Q9UEW8	STK39	T1038	E1039K	1039	Missense	proximal	1	no	93.526	110.424	EPSD	CCLE	61.825	Up-regulation
STE_STE20_FRAY_STK39_ST	Q9UHW9	SLC12A6	Q9UEW8	STK39	T1040	E1039K	1039	Missense	proximal	-1	no	97.170	95.942	EPSD	CCLE	61.825	Down-regulation
STE_STE20_FRAY_STK39_ST	Q9UHW9	SLC12A6	Q9UEW8	STK39	T1086	K1089R	1089	Missense	distal	3	no	66.052	66.607	EPSD	CCLE	61.825	Up-regulation
TKL_IRAK_IRAK1_ST	Q96FA3	PELI1	P51617	IRAK1	T86	E90K	90	Missense	distal	4	no	110.913	110.529	EPSD;PhosphoSitePlus	CCLE	67.712	Down-regulation
TKL_IRAK_IRAK1_ST	P51617	IRAK1	P51617	IRAK1	S131	S137F	137	Missense	distal	6	no	80.572	72.773	EPSD	CCLE	67.712	Down-regulation
TKL_IRAK_IRAK1_ST	Q9HAT8	PELI2	P51617	IRAK1	S78	L83V	83	Missense	distal	5	no	72.191	70.430	EPSD	CCLE	67.712	Down-regulation
TKL_IRAK_IRAK1_ST	Q9HAT8	PELI2	P51617	IRAK1	S80	L83V	83	Missense	distal	3	no	91.169	97.121	EPSD	CCLE	67.712	Up-regulation
TKL_IRAK_IRAK1_ST	Q9HAT8	PELI2	P51617	IRAK1	T82	L83V	83	Missense	proximal	1	no	113.740	111.868	EPSD	CCLE	67.712	Down-regulation
TKL_IRAK_IRAK1_ST	Q9HAT8	PELI2	P51617	IRAK1	S84	L83V	83	Missense	proximal	-1	no	75.820	69.230	EPSD	CCLE	67.712	Down-regulation
TKL_IRAK_IRAK1_ST	Q9HAT8	PELI2	P51617	IRAK1	T88	L83V	83	Missense	distal	-5	no	85.663	78.894	EPSD	CCLE	67.712	Down-regulation
TKL_IRAK_IRAK1_ST	Q9HAT8	PELI2	P51617	IRAK1	T88	Y93C	93	Missense	distal	5	no	85.663	85.722	EPSD	CCLE	67.712	Up-regulation
TKL_IRAK_IRAK1_ST	Q9HAT8	PELI2	P51617	IRAK1	S235	Q228H	228	Missense	distal	-7	no	78.469	79.702	EPSD	CCLE	67.712	Up-regulation
TKL_IRAK_IRAK1_ST	P40763	STAT3	P51617	IRAK1	T545	T545I	545	Missense	central	0	yes	71.747	0.000	EPSD	CCLE	67.712	Loss
CMGC_CDKL_CDKL5_ST	O76039	CDKL5	O76039	CDKL5	S526	T533A	533	Missense	distal	7	no	2.979	3.007	EPSD	CCLE	2.968	Up-regulation
CMGC_CDKL_CDKL5_ST	O76039	CDKL5	O76039	CDKL5	S768	K774R	774	Missense	distal	6	no	2.983	3.105	EPSD	CCLE	2.968	Up-regulation
CMGC_CDKL_CDKL5_ST	Q66K74	MAP1S	O76039	CDKL5	S646	P647T	647	Missense	proximal	1	no	3.021	2.951	EPSD	CCLE	2.968	Loss
CMGC_CDKL_CDKL5_ST	Q66K74	MAP1S	O76039	CDKL5	S651	P647T	647	Missense	distal	-4	no	3.564	3.630	EPSD	CCLE	2.968	Up-regulation
CMGC_CDKL_CDKL5_ST	Q66K74	MAP1S	O76039	CDKL5	S657	R660Q	660	Missense	distal	3	no	4.367	4.451	EPSD	CCLE	2.968	Up-regulation
CMGC_CDKL_CDKL5_ST	Q66K74	MAP1S	O76039	CDKL5	S657	A664V	664	Missense	distal	7	no	4.367	4.339	EPSD	CCLE	2.968	Down-regulation
CMGC_CDKL_CDKL5_ST	Q66K74	MAP1S	O76039	CDKL5	T671	A664V	664	Missense	distal	-7	no	5.202	4.869	EPSD	CCLE	2.968	Down-regulation
CMGC_CDKL_CDKL5_ST	Q66K74	MAP1S	O76039	CDKL5	T925	S931L	931	Missense	distal	6	no	5.304	4.870	EPSD	CCLE	2.968	Down-regulation
CMGC_CDKL_CDKL5_ST	Q66K74	MAP1S	O76039	CDKL5	T941	P943T	943	Missense	proximal	2	no	3.367	3.331	EPSD	CCLE	2.968	Down-regulation
CMGC_CDKL_CDKL5_ST	Q66K74	MAP1S	O76039	CDKL5	T941	P946L	946	Missense	distal	5	no	3.367	3.358	EPSD	CCLE	2.968	Down-regulation
CMGC_CDKL_CDKL5_ST	Q8TDM6	DLG5	O76039	CDKL5	S779	E776K	776	Missense	distal	-3	no	5.521	5.510	EPSD	CCLE	2.968	Down-regulation
CMGC_CDKL_CDKL5_ST	Q8TDM6	DLG5	O76039	CDKL5	T849	T849M	849	Missense	central	0	yes	4.364	0.000	EPSD	CCLE	2.968	Loss
CMGC_CDKL_CDKL5_ST	Q8TDM6	DLG5	O76039	CDKL5	T849	I846M	846	Missense	distal	-3	no	4.364	4.626	EPSD	CCLE	2.968	Up-regulation
CMGC_CDKL_CDKL5_ST	Q8TDM6	DLG5	O76039	CDKL5	S1076	S1075P	1075	Missense	proximal	-1	no	4.284	4.483	EPSD	CCLE	2.968	Up-regulation
CMGC_CDKL_CDKL5_ST	Q8TDM6	DLG5	O76039	CDKL5	S1700	D1705G	1705	Missense	distal	5	no	4.675	4.671	EPSD	CCLE	2.968	Down-regulation
CMGC_MAPK_p38_MAPK11_ST	P15336	ATF2	Q15759	MAPK11	T69	R74K	74	Missense	distal	5	no	47.733	47.657	PhosphoSitePlus;EPSD	CCLE	33.886	Down-regulation
CMGC_MAPK_p38_MAPK11_ST	P15336	ATF2	Q15759	MAPK11	T71	R74K	74	Missense	distal	3	no	48.904	49.784	EPSD;PhosphoSitePlus	CCLE	33.886	Up-regulation
CMGC_MAPK_p38_MAPK11_ST	P15336	ATF2	Q15759	MAPK11	S314	A319D	319	Missense	distal	5	no	35.026	35.599	EPSD	CCLE	33.886	Up-regulation
CMGC_MAPK_p38_MAPK11_ST	P15336	ATF2	Q15759	MAPK11	S314	S307L	307	Missense	distal	-7	no	35.026	34.801	EPSD	CCLE	33.886	Down-regulation
CMGC_MAPK_p38_MAPK11_ST	P15336	ATF2	Q15759	MAPK11	T325	A330G	330	Missense	distal	5	no	40.490	41.034	EPSD	CCLE	33.886	Up-regulation
CMGC_MAPK_p38_MAPK11_ST	P15336	ATF2	Q15759	MAPK11	T325	A319D	319	Missense	distal	-6	no	40.490	40.459	EPSD	CCLE	33.886	Down-regulation
CMGC_MAPK_p38_MAPK11_ST	P15336	ATF2	Q15759	MAPK11	S328	A330G	330	Missense	proximal	2	no	36.572	36.919	EPSD	CCLE	33.886	Up-regulation
CMGC_MAPK_p38_MAPK11_ST	P15336	ATF2	Q15759	MAPK11	T333	A330G	330	Missense	distal	-3	no	42.604	41.995	EPSD	CCLE	33.886	Down-regulation
CMGC_MAPK_p38_MAPK11_ST	Q15759	MAPK11	Q15759	MAPK11	S61	S56W	56	Missense	distal	-5	no	35.667	35.369	EPSD	CCLE	33.886	Down-regulation
CMGC_MAPK_p38_MAPK11_ST	O00418	EEF2K	Q15759	MAPK11	S359	S359C	359	Missense	central	0	yes	45.186	0.000	EPSD	CCLE	33.886	Loss
CMGC_MAPK_p38_MAPK11_ST	O00418	EEF2K	Q15759	MAPK11	T401	S404N	404	Missense	distal	3	no	39.858	39.235	EPSD	CCLE	33.886	Down-regulation
CMGC_MAPK_p38_MAPK11_ST	Q00613	HSF1	Q15759	MAPK11	S241	P243L	243	Missense	proximal	2	no	37.122	37.386	EPSD	CCLE	33.886	Up-regulation
CMGC_MAPK_p38_MAPK11_ST	Q00613	HSF1	Q15759	MAPK11	S292	R287M	287	Missense	distal	-5	no	44.972	45.004	EPSD	CCLE	33.886	Up-regulation
CMGC_MAPK_p38_MAPK11_ST	Q00613	HSF1	Q15759	MAPK11	T369	E371K	371	Missense	proximal	2	no	45.588	46.156	EPSD	CCLE	33.886	Up-regulation
CMGC_MAPK_p38_MAPK11_ST	Q00613	HSF1	Q15759	MAPK11	S419	V424M	424	Missense	distal	5	no	42.318	41.838	EPSD	CCLE	33.886	Down-regulation
CMGC_MAPK_p38_MAPK11_ST	Q8N122	RPTOR	Q15759	MAPK11	T731	R727G	727	Missense	distal	-4	no	37.316	36.069	EPSD	CCLE	33.886	Down-regulation
CMGC_MAPK_p38_MAPK11_ST	Q01094	E2F1	Q15759	MAPK11	S307	G309R	309	Missense	proximal	2	no	34.651	35.945	EPSD	CCLE	33.886	Up-regulation
CMGC_MAPK_p38_MAPK11_ST	Q01094	E2F1	Q15759	MAPK11	T311	G309R	309	Missense	proximal	-2	no	37.432	37.454	EPSD	CCLE	33.886	Up-regulation
CMGC_MAPK_p38_MAPK11_ST	Q01094	E2F1	Q15759	MAPK11	S375	R373S	373	Missense	proximal	-2	no	42.829	43.500	EPSD	CCLE	33.886	Up-regulation
CMGC_MAPK_p38_MAPK11_ST	Q01094	E2F1	Q15759	MAPK11	S403	L402F	402	Missense	proximal	-1	no	47.567	46.998	EPSD;PhosphoSitePlus	CCLE	33.886	Down-regulation
CMGC_MAPK_p38_MAPK11_ST	Q8IW41	MAPKAPK5	Q15759	MAPK11	S212	P213L	213	Missense	proximal	1	no	39.481	29.664	EPSD	CCLE	33.886	Loss
CMGC_MAPK_p38_MAPK11_ST	Q8IW41	MAPKAPK5	Q15759	MAPK11	T214	P213L	213	Missense	proximal	-1	no	41.160	40.805	EPSD	CCLE	33.886	Down-regulation
CMGC_MAPK_p38_MAPK11_ST	P30305	CDC25B	Q15759	MAPK11	S15	A13D	13	Missense	proximal	-2	no	40.733	40.637	EPSD	CCLE	33.886	Down-regulation
CMGC_MAPK_p38_MAPK11_ST	P30305	CDC25B	Q15759	MAPK11	S50	V44G	44	Missense	distal	-6	no	35.045	35.164	EPSD	CCLE	33.886	Up-regulation
CMGC_MAPK_p38_MAPK11_ST	P30305	CDC25B	Q15759	MAPK11	S50	R45Q	45	Missense	distal	-5	no	35.045	35.002	EPSD	CCLE	33.886	Down-regulation
CMGC_MAPK_p38_MAPK11_ST	P30305	CDC25B	Q15759	MAPK11	T54	M59I	59	Missense	distal	5	no	35.036	35.759	EPSD	CCLE	33.886	Up-regulation
CMGC_MAPK_p38_MAPK11_ST	P30305	CDC25B	Q15759	MAPK11	T69	K71E	71	Missense	proximal	2	no	38.212	37.645	EPSD	CCLE	33.886	Down-regulation
CMGC_MAPK_p38_MAPK11_ST	P30305	CDC25B	Q15759	MAPK11	T69	K71T	71	Missense	proximal	2	no	38.212	39.229	EPSD	CCLE	33.886	Up-regulation
CMGC_MAPK_p38_MAPK11_ST	P30305	CDC25B	Q15759	MAPK11	S321	C315F	315	Missense	distal	-6	no	45.485	45.512	EPSD	CCLE	33.886	Up-regulation
CMGC_MAPK_p38_MAPK11_ST	P30305	CDC25B	Q15759	MAPK11	S375	R372H	372	Missense	distal	-3	no	37.282	37.620	EPSD	CCLE	33.886	Up-regulation
CMGC_MAPK_p38_MAPK11_ST	P30305	CDC25B	Q15759	MAPK11	S416	L412H	412	Missense	distal	-4	no	34.071	35.262	EPSD	CCLE	33.886	Up-regulation
CMGC_MAPK_p38_MAPK11_ST	P41235	HNF4A	Q15759	MAPK11	S378	E372G	372	Missense	distal	-6	no	41.933	41.867	EPSD	CCLE	33.886	Down-regulation
CMGC_MAPK_p38_MAPK11_ST	P41235	HNF4A	Q15759	MAPK11	S436	G440S	440	Missense	distal	4	no	35.117	35.391	EPSD	CCLE	33.886	Up-regulation
CMGC_MAPK_p38_MAPK11_ST	P17544	ATF7	Q15759	MAPK11	S199	M197I	197	Missense	proximal	-2	no	38.754	38.228	EPSD	CCLE	33.886	Down-regulation
CMGC_MAPK_p38_MAPK11_ST	P17544	ATF7	Q15759	MAPK11	T327	R334W	334	Missense	distal	7	no	44.232	43.843	EPSD	CCLE	33.886	Down-regulation
CMGC_MAPK_p38_MAPK11_ST	P17544	ATF7	Q15759	MAPK11	S443	S448N	448	Missense	distal	5	no	34.985	35.583	EPSD	CCLE	33.886	Up-regulation
CMGC_MAPK_p38_MAPK11_ST	Q02156	PRKCE	Q15759	MAPK11	S329	E328Q	328	Missense	proximal	-1	no	42.861	42.620	EPSD	CCLE	33.886	Down-regulation
CMGC_MAPK_p38_MAPK11_ST	Q02156	PRKCE	Q15759	MAPK11	S350	I356L	356	Missense	distal	6	no	57.159	57.097	PhosphoSitePlus	CCLE	33.886	Down-regulation
CMGC_MAPK_p38_MAPK11_ST	Q01844	EWSR1	Q15759	MAPK11	T79	T75I	75	Missense	distal	-4	no	48.696	46.058	PhosphoSitePlus	CCLE	33.886	Down-regulation
CMGC_MAPK_p38_MAPK11_ST	P30281	CCND3	Q15759	MAPK11	S262	S259F	259	Missense	distal	-3	no	33.567	34.388	EPSD	CCLE	33.886	Gain
CMGC_MAPK_p38_MAPK11_ST	P30281	CCND3	Q15759	MAPK11	S264	S259F	259	Missense	distal	-5	no	37.891	37.599	EPSD	CCLE	33.886	Down-regulation
CMGC_MAPK_p38_MAPK11_ST	P04150	NR3C1	Q15759	MAPK11	T145	A146F	146	Missense	proximal	1	no	37.721	-0.675	EPSD	CCLE	33.886	Loss
CMGC_MAPK_p38_MAPK11_ST	P04150	NR3C1	Q15759	MAPK11	S395	S394L	394	Missense	proximal	-1	no	37.828	37.529	EPSD	CCLE	33.886	Down-regulation
CMGC_MAPK_p38_MAPK11_ST	P04150	NR3C1	Q15759	MAPK11	S395	G392D	392	Missense	distal	-3	no	37.828	38.215	EPSD	CCLE	33.886	Up-regulation
Other_NKF2_PINK1_ST	Q6NUN9	ZNF746	Q9BXM7	PINK1	S499	G502D	502	Missense	distal	3	no	13.659	14.486	EPSD	CCLE	11.649	Up-regulation
Other_NKF2_PINK1_ST	Q6NUN9	ZNF746	Q9BXM7	PINK1	S499	G494C	494	Missense	distal	-5	no	13.659	12.135	EPSD	CCLE	11.649	Down-regulation
Other_NKF2_PINK1_ST	Q6NUN9	ZNF746	Q9BXM7	PINK1	T561	D555G	555	Missense	distal	-6	no	10.121	12.349	EPSD	CCLE	11.649	Gain
Other_NKF2_PINK1_ST	O95202	LETM1	Q9BXM7	PINK1	T192	R194Q	194	Missense	proximal	2	no	25.697	28.057	PhosphoSitePlus	CCLE	11.649	Up-regulation
Other_NKF2_PINK1_ST	O95202	LETM1	Q9BXM7	PINK1	T192	T192P	192	Missense	central	0	yes	25.697	0.000	PhosphoSitePlus	CCLE	11.649	Loss
Other_NKF2_PINK1_ST	O95202	LETM1	Q9BXM7	PINK1	T436	P441S	441	Missense	distal	5	no	11.947	11.021	EPSD	CCLE	11.649	Loss
Other_NKF2_PINK1_ST	O95202	LETM1	Q9BXM7	PINK1	T436	P429A	429	Missense	distal	-7	no	11.947	11.937	EPSD	CCLE	11.649	Down-regulation
TKL_RAF_RAF_RAF1_ST	P04049	RAF1	P04049	RAF1	S12	F17L	17	Missense	distal	5	no	9.852	9.673	EPSD	CCLE	7.934	Down-regulation
TKL_RAF_RAF_RAF1_ST	P04049	RAF1	P04049	RAF1	T268	P271H	271	Missense	distal	3	no	13.672	13.923	EPSD	CCLE	7.934	Up-regulation
TKL_RAF_RAF_RAF1_ST	Q13118	KLF10	P04049	RAF1	T93	T93N	93	Missense	central	0	yes	13.824	0.000	PhosphoSitePlus	CCLE	7.934	Loss
TKL_RAF_RAF_RAF1_ST	Q13118	KLF10	P04049	RAF1	T394	R391G	391	Missense	distal	-3	no	8.435	0.926	EPSD	CCLE	7.934	Loss
TKL_RAF_RAF_RAF1_ST	Q92934	BAD	P04049	RAF1	S75	H73Q	73	Missense	proximal	-2	no	17.199	17.366	PhosphoSitePlus;EPSD	CCLE	7.934	Up-regulation
TKL_RAF_RAF_RAF1_ST	Q92934	BAD	P04049	RAF1	S75	R70W	70	Missense	distal	-5	no	17.199	17.011	PhosphoSitePlus;EPSD	CCLE	7.934	Down-regulation
TKL_RAF_RAF_RAF1_ST	Q05639	EEF1A2	P04049	RAF1	S358	S354G	354	Missense	distal	-4	no	9.098	8.126	EPSD	CCLE	7.934	Down-regulation
TKL_RAF_RAF_RAF1_ST	P01106	MYC	P04049	RAF1	S6	R10T	10	Missense	distal	4	no	8.735	9.507	EPSD	CCLE	7.934	Up-regulation
TKL_RAF_RAF_RAF1_ST	P01106	MYC	P04049	RAF1	S6	N11K	11	Missense	distal	5	no	8.735	8.615	EPSD	CCLE	7.934	Down-regulation
TKL_RAF_RAF_RAF1_ST	P01106	MYC	P04049	RAF1	T8	R10T	10	Missense	proximal	2	no	14.011	14.464	PhosphoSitePlus	CCLE	7.934	Up-regulation
TKL_RAF_RAF_RAF1_ST	P01106	MYC	P04049	RAF1	T8	N11K	11	Missense	distal	3	no	14.011	13.235	PhosphoSitePlus	CCLE	7.934	Down-regulation
TKL_RAF_RAF_RAF1_ST	P01106	MYC	P04049	RAF1	S159	Q153R	153	Missense	distal	-6	no	8.148	8.135	EPSD	CCLE	7.934	Down-regulation
TKL_RAF_RAF_RAF1_ST	P01106	MYC	P04049	RAF1	S202	K206T	206	Missense	distal	4	no	9.051	9.634	EPSD	CCLE	7.934	Up-regulation
TKL_RAF_RAF_RAF1_ST	O14974	PPP1R12A	P04049	RAF1	S472	S477A	477	Missense	distal	5	no	8.586	8.729	EPSD	CCLE	7.934	Up-regulation
TKL_RAF_RAF_RAF1_ST	O14974	PPP1R12A	P04049	RAF1	S520	D518E	518	Missense	proximal	-2	no	8.204	8.230	EPSD	CCLE	7.934	Up-regulation
TKL_RAF_RAF_RAF1_ST	O14974	PPP1R12A	P04049	RAF1	S525	D518E	518	Missense	distal	-7	no	10.526	10.427	EPSD	CCLE	7.934	Down-regulation
TKL_RAF_RAF_RAF1_ST	O14974	PPP1R12A	P04049	RAF1	S585	S591G	591	Missense	distal	6	no	9.716	9.624	EPSD	CCLE	7.934	Down-regulation
CAMK_MAPKAPK_MK2_MAPKAPK2_ST	Q8N5C8	TAB3	P49137	MAPKAPK2	S82	P86S	86	Missense	distal	4	no	12.230	12.289	EPSD	CCLE	11.681	Up-regulation
CAMK_MAPKAPK_MK2_MAPKAPK2_ST	Q8N5C8	TAB3	P49137	MAPKAPK2	S82	S82R	82	Missense	central	0	yes	12.230	0.000	EPSD	CCLE	11.681	Loss
CAMK_MAPKAPK_MK2_MAPKAPK2_ST	Q8N5C8	TAB3	P49137	MAPKAPK2	S356	S359P	359	Missense	distal	3	no	12.174	12.167	EPSD	CCLE	11.681	Down-regulation
CAMK_MAPKAPK_MK2_MAPKAPK2_ST	Q8N5C8	TAB3	P49137	MAPKAPK2	S357	S359P	359	Missense	proximal	2	no	12.050	11.858	EPSD	CCLE	11.681	Down-regulation
CAMK_MAPKAPK_MK2_MAPKAPK2_ST	Q8N5C8	TAB3	P49137	MAPKAPK2	S359	S359P	359	Missense	central	0	yes	11.696	0.000	EPSD	CCLE	11.681	Loss
CAMK_MAPKAPK_MK2_MAPKAPK2_ST	Q8N5C8	TAB3	P49137	MAPKAPK2	S504	G497R	497	Missense	distal	-7	no	11.715	11.622	EPSD	CCLE	11.681	Loss
CAMK_MAPKAPK_MK2_MAPKAPK2_ST	P30305	CDC25B	P49137	MAPKAPK2	S91	S95Y	95	Missense	distal	4	no	13.750	13.396	EPSD	CCLE	11.681	Down-regulation
CAMK_MAPKAPK_MK2_MAPKAPK2_ST	P30305	CDC25B	P49137	MAPKAPK2	S375	R372H	372	Missense	distal	-3	no	19.277	14.518	EPSD;PhosphoSitePlus	CCLE	11.681	Down-regulation
CAMK_MAPKAPK_MK2_MAPKAPK2_ST	P17302	GJA1	P49137	MAPKAPK2	S251	P246T	246	Missense	distal	-5	no	12.263	12.192	EPSD	CCLE	11.681	Down-regulation
CAMK_MAPKAPK_MK2_MAPKAPK2_ST	P04792	HSPB1	P49137	MAPKAPK2	S74	S78T	78	Missense	distal	4	no	13.380	13.428	EPSD	CCLE	11.681	Up-regulation
CAMK_MAPKAPK_MK2_MAPKAPK2_ST	P04792	HSPB1	P49137	MAPKAPK2	S82	S78T	78	Missense	distal	-4	no	17.328	17.339	EPSD;PhosphoSitePlus	CCLE	11.681	Up-regulation
CAMK_MAPKAPK_MK2_MAPKAPK2_ST	Q96J92	WNK4	P49137	MAPKAPK2	S47	G48W	48	Missense	proximal	1	no	16.734	17.050	EPSD	CCLE	11.681	Up-regulation
CAMK_MAPKAPK_MK2_MAPKAPK2_ST	Q96J92	WNK4	P49137	MAPKAPK2	S1053	E1057A	1057	Missense	distal	4	no	14.462	14.543	EPSD	CCLE	11.681	Up-regulation
CAMK_MAPKAPK_MK2_MAPKAPK2_ST	Q96J92	WNK4	P49137	MAPKAPK2	S1190	S1183P	1183	Missense	distal	-7	no	17.327	17.325	EPSD	CCLE	11.681	Down-regulation
CAMK_MAPKAPK_MK2_MAPKAPK2_ST	Q96J92	WNK4	P49137	MAPKAPK2	S1190	F1194S	1194	Missense	distal	4	no	17.327	17.638	EPSD	CCLE	11.681	Up-regulation
CAMK_MAPKAPK_MK2_MAPKAPK2_ST	Q96J92	WNK4	P49137	MAPKAPK2	S1201	F1194S	1194	Missense	distal	-7	no	17.888	17.798	EPSD	CCLE	11.681	Down-regulation
CAMK_MAPKAPK_MK2_MAPKAPK2_ST	Q6JBY9	RCSD1	P49137	MAPKAPK2	S179	D186G	186	Missense	distal	7	no	19.154	19.061	PhosphoSitePlus;EPSD	CCLE	11.681	Down-regulation
CAMK_MAPKAPK_MK2_MAPKAPK2_ST	Q6JBY9	RCSD1	P49137	MAPKAPK2	S298	S298R	298	Missense	central	0	yes	16.417	0.000	EPSD	CCLE	11.681	Loss
CAMK_MAPKAPK_MK2_MAPKAPK2_ST	Q6JBY9	RCSD1	P49137	MAPKAPK2	S298	A305V	305	Missense	distal	7	no	16.417	15.993	EPSD	CCLE	11.681	Down-regulation
CAMK_MAPKAPK_MK2_MAPKAPK2_ST	O95816	BAG2	P49137	MAPKAPK2	S143	S143P	143	Missense	central	0	yes	12.085	0.000	EPSD	CCLE	11.681	Loss
CAMK_MAPKAPK_MK2_MAPKAPK2_ST	Q00987	MDM2	P49137	MAPKAPK2	S40	D46N	46	Missense	distal	6	no	12.898	12.905	EPSD	CCLE	11.681	Up-regulation
CAMK_MAPKAPK_MK2_MAPKAPK2_ST	O00418	EEF2K	P49137	MAPKAPK2	S366	S359C	359	Missense	distal	-7	no	16.411	16.456	EPSD	CCLE	11.681	Up-regulation
CAMK_MAPKAPK_MK2_MAPKAPK2_ST	O00418	EEF2K	P49137	MAPKAPK2	S398	S404N	404	Missense	distal	6	no	12.900	12.875	EPSD	CCLE	11.681	Down-regulation
CAMK_MAPKAPK_MK2_MAPKAPK2_ST	O00418	EEF2K	P49137	MAPKAPK2	S462	R457Q	457	Missense	distal	-5	no	12.213	11.495	EPSD	CCLE	11.681	Loss
CAMK_MAPKAPK_MK2_MAPKAPK2_ST	O00418	EEF2K	P49137	MAPKAPK2	S462	E458G	458	Missense	distal	-4	no	12.213	12.462	EPSD	CCLE	11.681	Up-regulation
CAMK_MAPKAPK_MK2_MAPKAPK2_ST	O00418	EEF2K	P49137	MAPKAPK2	S464	R457Q	457	Missense	distal	-7	no	12.912	12.999	EPSD	CCLE	11.681	Up-regulation
CAMK_MAPKAPK_MK2_MAPKAPK2_ST	O00418	EEF2K	P49137	MAPKAPK2	S464	E458G	458	Missense	distal	-6	no	12.912	12.990	EPSD	CCLE	11.681	Up-regulation
CAMK_MAPKAPK_MK2_MAPKAPK2_ST	P07101	TH	P49137	MAPKAPK2	S71	R68H	68	Missense	distal	-3	no	19.024	14.265	EPSD;PhosphoSitePlus	CCLE	11.681	Down-regulation
CAMK_MAPKAPK_MK2_MAPKAPK2_ST	P07101	TH	P49137	MAPKAPK2	S71	R68C	68	Missense	distal	-3	no	19.024	10.624	EPSD;PhosphoSitePlus	CCLE	11.681	Loss
CAMK_MAPKAPK_MK2_MAPKAPK2_ST	P07101	TH	P49137	MAPKAPK2	S435	P438L	438	Missense	distal	3	no	13.210	13.101	EPSD	CCLE	11.681	Down-regulation
CAMK_MAPKAPK_MK2_MAPKAPK2_ST	P05783	KRT18	P49137	MAPKAPK2	S49	R45W	45	Missense	distal	-4	no	14.733	14.951	EPSD	CCLE	11.681	Up-regulation
CAMK_MAPKAPK_MK2_MAPKAPK2_ST	P05783	KRT18	P49137	MAPKAPK2	S51	R45W	45	Missense	distal	-6	no	13.030	13.076	EPSD	CCLE	11.681	Up-regulation
CAMK_MAPKAPK_MK2_MAPKAPK2_ST	P18615	NELFE	P49137	MAPKAPK2	S37	S37R	37	Missense	central	0	yes	11.861	0.000	EPSD	CCLE	11.681	Loss
CAMK_MAPKAPK_MK2_MAPKAPK2_ST	P18615	NELFE	P49137	MAPKAPK2	S39	S37R	37	Missense	proximal	-2	no	12.722	10.455	EPSD	CCLE	11.681	Loss
CAMK_MAPKAPK_MK2_MAPKAPK2_ST	P18615	NELFE	P49137	MAPKAPK2	T40	S37R	37	Missense	distal	-3	no	8.949	15.279	EPSD	CCLE	11.681	Gain
CAMK_MAPKAPK_MK2_MAPKAPK2_ST	P18615	NELFE	P49137	MAPKAPK2	S123	R126C	126	Missense	distal	3	no	13.347	13.297	EPSD	CCLE	11.681	Down-regulation
CAMK_MAPKAPK_MK2_MAPKAPK2_ST	P18615	NELFE	P49137	MAPKAPK2	S251	R255L	255	Missense	distal	4	no	19.741	19.653	EPSD;PhosphoSitePlus	CCLE	11.681	Down-regulation
CAMK_MAPKAPK_MK2_MAPKAPK2_ST	Q07352	ZFP36L1	P49137	MAPKAPK2	T148	R149H	149	Missense	proximal	1	no	14.848	14.460	EPSD	CCLE	11.681	Down-regulation
CAMK_MAPKAPK_MK2_MAPKAPK2_ST	Q9NQC3	RTN4	P49137	MAPKAPK2	S150	V151A	151	Missense	proximal	1	no	11.742	11.493	EPSD	CCLE	11.681	Loss
CAMK_MAPKAPK_MK2_MAPKAPK2_ST	Q9NQC3	RTN4	P49137	MAPKAPK2	S150	P146H	146	Missense	distal	-4	no	11.742	11.914	EPSD	CCLE	11.681	Up-regulation
CAMK_MAPKAPK_MK2_MAPKAPK2_ST	Q9NQC3	RTN4	P49137	MAPKAPK2	S150	P146S	146	Missense	distal	-4	no	11.742	11.663	EPSD	CCLE	11.681	Loss
CAMK_MAPKAPK_MK2_MAPKAPK2_ST	Q9NQC3	RTN4	P49137	MAPKAPK2	S181	R179W	179	Missense	proximal	-2	no	18.474	16.724	EPSD	CCLE	11.681	Down-regulation
CAMK_MAPKAPK_MK2_MAPKAPK2_ST	Q9NQC3	RTN4	P49137	MAPKAPK2	S182	R179W	179	Missense	distal	-3	no	16.368	7.789	EPSD	CCLE	11.681	Loss
CAMK_MAPKAPK_MK2_MAPKAPK2_ST	Q9NQC3	RTN4	P49137	MAPKAPK2	S184	R179W	179	Missense	distal	-5	no	15.518	15.163	EPSD	CCLE	11.681	Down-regulation
CAMK_MAPKAPK_MK2_MAPKAPK2_ST	Q9NQC3	RTN4	P49137	MAPKAPK2	S196	R201P	201	Missense	distal	5	no	14.712	14.776	EPSD	CCLE	11.681	Up-regulation
CAMK_MAPKAPK_MK2_MAPKAPK2_ST	Q9NQC3	RTN4	P49137	MAPKAPK2	S196	P193L	193	Missense	distal	-3	no	14.712	14.287	EPSD	CCLE	11.681	Down-regulation
CAMK_MAPKAPK_MK2_MAPKAPK2_ST	P53350	PLK1	P49137	MAPKAPK2	S326	F325V	325	Missense	proximal	-1	no	12.908	12.894	PhosphoSitePlus;EPSD	CCLE	11.681	Down-regulation
CAMK_MAPKAPK_MK2_MAPKAPK2_ST	P53350	PLK1	P49137	MAPKAPK2	S330	F325V	325	Missense	distal	-5	no	12.702	13.092	EPSD	CCLE	11.681	Up-regulation
CAMK_MAPKAPK_MK2_MAPKAPK2_ST	Q14134	TRIM29	P49137	MAPKAPK2	S21	S28I	28	Missense	distal	7	no	12.763	12.499	EPSD	CCLE	11.681	Down-regulation
CAMK_MAPKAPK_MK2_MAPKAPK2_ST	Q14134	TRIM29	P49137	MAPKAPK2	S21	P25L	25	Missense	distal	4	no	12.763	12.669	EPSD	CCLE	11.681	Down-regulation
CAMK_MAPKAPK_MK2_MAPKAPK2_ST	Q14134	TRIM29	P49137	MAPKAPK2	S23	S28I	28	Missense	distal	5	no	18.844	19.048	EPSD	CCLE	11.681	Up-regulation
CAMK_MAPKAPK_MK2_MAPKAPK2_ST	Q14134	TRIM29	P49137	MAPKAPK2	S23	P25L	25	Missense	proximal	2	no	18.844	18.622	EPSD	CCLE	11.681	Down-regulation
CAMK_MAPKAPK_MK2_MAPKAPK2_ST	Q14134	TRIM29	P49137	MAPKAPK2	S28	S28I	28	Missense	central	0	yes	16.012	0.000	EPSD	CCLE	11.681	Loss
CAMK_MAPKAPK_MK2_MAPKAPK2_ST	Q14134	TRIM29	P49137	MAPKAPK2	S28	P25L	25	Missense	distal	-3	no	16.012	15.586	EPSD	CCLE	11.681	Down-regulation
CAMK_MAPKAPK_MK2_MAPKAPK2_ST	O95453	PARN	P49137	MAPKAPK2	S61	K58R	58	Missense	distal	-3	no	8.731	13.855	EPSD	CCLE	11.681	Gain
CAMK_MAPKAPK_MK2_MAPKAPK2_ST	O95453	PARN	P49137	MAPKAPK2	S151	K149Q	149	Missense	proximal	-2	no	9.586	11.767	EPSD	CCLE	11.681	Gain
CAMK_MAPKAPK_MK2_MAPKAPK2_ST	Q13546	RIPK1	P49137	MAPKAPK2	S320	A327T	327	Missense	distal	7	no	17.125	17.226	PhosphoSitePlus	CCLE	11.681	Up-regulation
CAMK_MAPKAPK_MK2_MAPKAPK2_ST	P11831	SRF	P49137	MAPKAPK2	T27	S21N	21	Missense	distal	-6	no	14.318	14.391	EPSD	CCLE	11.681	Up-regulation
CAMK_MAPKAPK_MK2_MAPKAPK2_ST	P11831	SRF	P49137	MAPKAPK2	S79	G73R	73	Missense	distal	-6	no	14.467	14.395	EPSD	CCLE	11.681	Down-regulation
CAMK_MAPKAPK_MK2_MAPKAPK2_ST	Q13263	TRIM28	P49137	MAPKAPK2	S37	S37L	37	Missense	central	0	yes	12.267	0.000	EPSD	CCLE	11.681	Loss
CAMK_MAPKAPK_MK2_MAPKAPK2_ST	Q13263	TRIM28	P49137	MAPKAPK2	S37	A38V	38	Missense	proximal	1	no	12.267	12.517	EPSD	CCLE	11.681	Up-regulation
CAMK_MAPKAPK_MK2_MAPKAPK2_ST	Q13263	TRIM28	P49137	MAPKAPK2	S37	S41W	41	Missense	distal	4	no	12.267	12.092	EPSD	CCLE	11.681	Down-regulation
CAMK_MAPKAPK_MK2_MAPKAPK2_ST	Q13263	TRIM28	P49137	MAPKAPK2	S37	A44P	44	Missense	distal	7	no	12.267	12.184	EPSD	CCLE	11.681	Down-regulation
CAMK_MAPKAPK_MK2_MAPKAPK2_ST	Q13263	TRIM28	P49137	MAPKAPK2	S43	A38V	38	Missense	distal	-5	no	11.362	12.033	EPSD	CCLE	11.681	Gain
CAMK_MAPKAPK_MK2_MAPKAPK2_ST	Q13263	TRIM28	P49137	MAPKAPK2	S49	A46S	46	Missense	distal	-3	no	9.791	12.682	EPSD	CCLE	11.681	Gain
CAMK_MAPKAPK_MK2_MAPKAPK2_ST	P33241	LSP1	P49137	MAPKAPK2	S177	Q171K	171	Missense	distal	-6	no	17.187	17.189	EPSD	CCLE	11.681	Up-regulation
CAMK_MAPKAPK_MK2_MAPKAPK2_ST	O75925	PIAS1	P49137	MAPKAPK2	S485	C481Y	481	Missense	distal	-4	no	14.895	15.000	EPSD	CCLE	11.681	Up-regulation
CAMK_MAPKAPK_MK2_MAPKAPK2_ST	O75925	PIAS1	P49137	MAPKAPK2	T487	C481Y	481	Missense	distal	-6	no	11.846	11.886	EPSD	CCLE	11.681	Up-regulation
CAMK_MAPKAPK_MK2_MAPKAPK2_ST	O75925	PIAS1	P49137	MAPKAPK2	S522	L523R	523	Missense	proximal	1	no	12.530	12.352	PhosphoSitePlus	CCLE	11.681	Down-regulation
CAMK_MAPKAPK_MK2_MAPKAPK2_ST	Q9NY61	AATF	P49137	MAPKAPK2	T412	T410I	410	Missense	proximal	-2	no	13.095	10.508	EPSD	CCLE	11.681	Loss
CAMK_MAPKAPK_MK2_MAPKAPK2_ST	Q00613	HSF1	P49137	MAPKAPK2	S248	P243L	243	Missense	distal	-5	no	12.237	12.742	EPSD	CCLE	11.681	Up-regulation
CAMK_MAPKAPK_MK2_MAPKAPK2_ST	Q00613	HSF1	P49137	MAPKAPK2	S250	P243L	243	Missense	distal	-7	no	13.284	13.319	EPSD	CCLE	11.681	Up-regulation
CAMK_MAPKAPK_MK2_MAPKAPK2_ST	Q00613	HSF1	P49137	MAPKAPK2	S290	R287M	287	Missense	distal	-3	no	15.437	7.046	EPSD	CCLE	11.681	Loss
CAMK_MAPKAPK_MK2_MAPKAPK2_ST	Q00613	HSF1	P49137	MAPKAPK2	S292	R287M	287	Missense	distal	-5	no	15.145	14.730	EPSD	CCLE	11.681	Down-regulation
CAMK_MAPKAPK_MK2_MAPKAPK2_ST	Q00613	HSF1	P49137	MAPKAPK2	S375	E371K	371	Missense	distal	-4	no	11.602	11.770	EPSD	CCLE	11.681	Gain
CAMK_MAPKAPK_MK2_MAPKAPK2_ST	Q00613	HSF1	P49137	MAPKAPK2	S518	A523D	523	Missense	distal	5	no	12.535	12.769	EPSD	CCLE	11.681	Up-regulation
CAMK_MAPKAPK_MK2_MAPKAPK2_ST	Q07817	BCL2L1	P49137	MAPKAPK2	S49	E42D	42	Missense	distal	-7	no	13.185	13.224	EPSD	CCLE	11.681	Up-regulation
CAMK_MAPKAPK_MK2_MAPKAPK2_ST	Q07817	BCL2L1	P49137	MAPKAPK2	S62	S62N	62	Missense	central	0	yes	12.896	0.000	PhosphoSitePlus	CCLE	11.681	Loss
CAMK_MAPKAPK_MK2_MAPKAPK2_ST	Q16875	PFKFB3	P49137	MAPKAPK2	S211	D207G	207	Missense	distal	-4	no	14.175	14.252	EPSD	CCLE	11.681	Up-regulation
CAMK_MAPKAPK_MK2_MAPKAPK2_ST	P49815	TSC2	P49137	MAPKAPK2	S540	R537P	537	Missense	distal	-3	no	19.462	14.797	EPSD	CCLE	11.681	Down-regulation
CAMK_MAPKAPK_MK2_MAPKAPK2_ST	P49815	TSC2	P49137	MAPKAPK2	S540	S538F	538	Missense	proximal	-2	no	19.462	14.035	EPSD	CCLE	11.681	Down-regulation
CAMK_MAPKAPK_MK2_MAPKAPK2_ST	P49815	TSC2	P49137	MAPKAPK2	S609	T603P	603	Missense	distal	-6	no	12.074	12.090	EPSD	CCLE	11.681	Up-regulation
CAMK_MAPKAPK_MK2_MAPKAPK2_ST	P49815	TSC2	P49137	MAPKAPK2	S999	L995I	995	Missense	distal	-4	no	13.470	13.409	EPSD	CCLE	11.681	Down-regulation
CAMK_MAPKAPK_MK2_MAPKAPK2_ST	P49815	TSC2	P49137	MAPKAPK2	S999	N1006S	1006	Missense	distal	7	no	13.470	13.760	EPSD	CCLE	11.681	Up-regulation
CAMK_MAPKAPK_MK2_MAPKAPK2_ST	P49815	TSC2	P49137	MAPKAPK2	S1130	L1137P	1137	Missense	distal	7	no	16.204	16.678	EPSD	CCLE	11.681	Up-regulation
CAMK_MAPKAPK_MK2_MAPKAPK2_ST	P49815	TSC2	P49137	MAPKAPK2	S1132	L1137P	1137	Missense	distal	5	no	18.682	18.595	EPSD	CCLE	11.681	Down-regulation
CAMK_MAPKAPK_MK2_MAPKAPK2_ST	P49815	TSC2	P49137	MAPKAPK2	S1346	V1353D	1353	Missense	distal	7	no	12.473	12.585	EPSD	CCLE	11.681	Up-regulation
CAMK_MAPKAPK_MK2_MAPKAPK2_ST	P49815	TSC2	P49137	MAPKAPK2	S1364	E1366K	1366	Missense	proximal	2	no	14.445	14.146	EPSD	CCLE	11.681	Down-regulation
CAMK_MAPKAPK_MK2_MAPKAPK2_ST	P49815	TSC2	P49137	MAPKAPK2	S1418	A1416V	1416	Missense	proximal	-2	no	12.237	10.036	EPSD	CCLE	11.681	Loss
CAMK_MAPKAPK_MK2_MAPKAPK2_ST	P49815	TSC2	P49137	MAPKAPK2	S1420	A1416V	1416	Missense	distal	-4	no	18.558	18.637	EPSD	CCLE	11.681	Up-regulation
CAMK_MAPKAPK_MK2_MAPKAPK2_ST	P49815	TSC2	P49137	MAPKAPK2	S1454	P1458T	1458	Missense	distal	4	no	18.407	18.514	EPSD	CCLE	11.681	Up-regulation
CAMK_MAPKAPK_MK2_MAPKAPK2_ST	P49815	TSC2	P49137	MAPKAPK2	T1462	P1458T	1458	Missense	distal	-4	no	14.028	13.959	EPSD	CCLE	11.681	Down-regulation
CAMK_MAPKAPK_MK2_MAPKAPK2_ST	P49815	TSC2	P49137	MAPKAPK2	S1464	P1458T	1458	Missense	distal	-6	no	13.136	13.120	EPSD	CCLE	11.681	Down-regulation
CAMK_MAPKAPK_MK2_MAPKAPK2_ST	P30307	CDC25C	P49137	MAPKAPK2	S449	G456R	456	Missense	distal	7	no	13.827	14.060	EPSD	CCLE	11.681	Up-regulation
CAMK_MAPKAPK_MK2_MAPKAPK2_ST	P30307	CDC25C	P49137	MAPKAPK2	S451	G456R	456	Missense	distal	5	no	18.092	17.821	EPSD	CCLE	11.681	Down-regulation
CAMK_MAPKAPK_MK2_MAPKAPK2_ST	Q14457	BECN1	P49137	MAPKAPK2	S64	P68S	68	Missense	distal	4	no	11.915	11.974	EPSD	CCLE	11.681	Up-regulation
CAMK_MAPKAPK_MK2_MAPKAPK2_ST	Q14457	BECN1	P49137	MAPKAPK2	S64	T62A	62	Missense	proximal	-2	no	11.915	12.074	EPSD	CCLE	11.681	Up-regulation
CAMK_MAPKAPK_MK2_MAPKAPK2_ST	Q14457	BECN1	P49137	MAPKAPK2	S90	S93N	93	Missense	distal	3	no	16.933	16.776	PhosphoSitePlus	CCLE	11.681	Down-regulation
CAMK_MAPKAPK_MK2_MAPKAPK2_ST	Q14457	BECN1	P49137	MAPKAPK2	S96	S93N	93	Missense	distal	-3	no	13.051	12.835	EPSD	CCLE	11.681	Down-regulation
CAMK_MAPKAPK_MK2_MAPKAPK2_ST	P35900	KRT20	P49137	MAPKAPK2	S13	A18V	18	Missense	distal	5	no	19.361	19.504	PhosphoSitePlus	CCLE	11.681	Up-regulation
CAMK_MAPKAPK_MK2_MAPKAPK2_ST	P35900	KRT20	P49137	MAPKAPK2	S15	A18V	18	Missense	distal	3	no	13.805	13.701	EPSD	CCLE	11.681	Down-regulation
CAMK_MAPKAPK_MK2_MAPKAPK2_ST	P35900	KRT20	P49137	MAPKAPK2	S83	Y84H	84	Missense	proximal	1	no	13.206	13.395	EPSD	CCLE	11.681	Up-regulation
CAMK_MAPKAPK_MK2_MAPKAPK2_ST	P35900	KRT20	P49137	MAPKAPK2	S118	S118N	118	Missense	central	0	yes	12.619	0.000	EPSD	CCLE	11.681	Loss
CAMK_CAMKL_MARK_MARK3_ST	P27448	MARK3	P27448-3	MARK3	S436	P433A	433	Missense	distal	-3	no	265.635	270.589	EPSD	CCLE	255.132	Up-regulation
CAMK_CAMKL_MARK_MARK3_ST	P27448	MARK3	P27448-3	MARK3	S436	P433L	433	Missense	distal	-3	no	265.635	249.127	EPSD	CCLE	255.132	Loss
CAMK_CAMKL_MARK_MARK3_ST	P27448	MARK3	P27448-3	MARK3	T438	P433L	433	Missense	distal	-5	no	166.157	274.060	EPSD	CCLE	255.132	Gain
CAMK_CAMKL_MARK_MARK3_ST	P27448	MARK3	P27448-3	MARK3	S598	T602A	602	Missense	distal	4	no	498.268	498.033	EPSD;PhosphoSitePlus	CCLE	255.132	Down-regulation
CAMK_CAMKL_MARK_MARK3_ST	P27448	MARK3	P27448-3	MARK3	S601	T602A	602	Missense	proximal	1	no	377.882	377.886	PhosphoSitePlus;EPSD	CCLE	255.132	Up-regulation
CAMK_CAMKL_MARK_MARK3_ST	P27448	MARK3	P27448-3	MARK3	T602	T602A	602	Missense	central	0	yes	369.966	0.000	EPSD;PhosphoSitePlus	CCLE	255.132	Loss
CAMK_CAMKL_MARK_MARK3_ST	P27448	MARK3	P27448-3	MARK3	S606	T602A	602	Missense	distal	-4	no	332.106	337.648	EPSD;PhosphoSitePlus	CCLE	255.132	Up-regulation
CAMK_CAMKL_MARK_MARK3_ST	P27448	MARK3	P27448-3	MARK3	S724	L723P	723	Missense	proximal	-1	no	353.601	353.267	EPSD	CCLE	255.132	Down-regulation
CK1_CK1_CK1-G_CSNK1G2_ST	Q14457	BECN1	P78368	CSNK1G2	S96	S93N	93	Missense	distal	-3	no	3.351	3.349	EPSD	CCLE	1.578	Down-regulation
CK1_CK1_CK1-G_CSNK1G2_ST	P84022	SMAD3	P78368	CSNK1G2	T388	Q387H	387	Missense	proximal	-1	no	3.568	3.601	EPSD	CCLE	1.578	Up-regulation
CK1_CK1_CK1-G_CSNK1G2_ST	O14654	IRS4	P78368	CSNK1G2	S804	Y808C	808	Missense	distal	4	no	1.640	1.471	EPSD	CCLE	1.578	Loss
AGC_PKC_PKCd_PRKCQ_ST	Q92934	BAD	Q04759	PRKCQ	S74	H73Q	73	Missense	proximal	-1	no	1.454	1.455	EPSD	CCLE	1.204	Up-regulation
AGC_PKC_PKCd_PRKCQ_ST	Q92934	BAD	Q04759	PRKCQ	S74	R70W	70	Missense	distal	-4	no	1.454	1.398	EPSD	CCLE	1.204	Down-regulation
AGC_PKC_PKCd_PRKCQ_ST	Q92934	BAD	Q04759	PRKCQ	S75	H73Q	73	Missense	proximal	-2	no	2.338	2.284	PhosphoSitePlus;EPSD	CCLE	1.204	Down-regulation
AGC_PKC_PKCd_PRKCQ_ST	Q92934	BAD	Q04759	PRKCQ	S75	R70W	70	Missense	distal	-5	no	2.338	2.076	PhosphoSitePlus;EPSD	CCLE	1.204	Down-regulation
AGC_PKC_PKCd_PRKCQ_ST	Q04759	PRKCQ	Q04759	PRKCQ	S695	P699S	699	Missense	distal	4	no	1.753	1.739	EPSD	CCLE	1.204	Down-regulation
AGC_PKC_PKCd_PRKCQ_ST	Q04759	PRKCQ	Q04759	PRKCQ	S706	P699S	699	Missense	distal	-7	no	1.770	1.774	EPSD	CCLE	1.204	Up-regulation
AGC_PKC_PKCd_PRKCQ_ST	P35568	IRS1	Q04759	PRKCQ	S24	L19R	19	Missense	distal	-5	no	1.549	1.824	EPSD	CCLE	1.204	Up-regulation
AGC_PKC_PKCd_PRKCQ_ST	P35568	IRS1	Q04759	PRKCQ	S268	S273L	273	Missense	distal	5	no	1.946	1.941	EPSD	CCLE	1.204	Down-regulation
AGC_PKC_PKCd_PRKCQ_ST	P35568	IRS1	Q04759	PRKCQ	S270	S273L	273	Missense	distal	3	no	2.580	2.571	EPSD	CCLE	1.204	Down-regulation
AGC_PKC_PKCd_PRKCQ_ST	P35568	IRS1	Q04759	PRKCQ	S272	S273L	273	Missense	proximal	1	no	1.399	1.395	EPSD	CCLE	1.204	Down-regulation
AGC_PKC_PKCd_PRKCQ_ST	P35568	IRS1	Q04759	PRKCQ	T305	R304H	304	Missense	proximal	-1	no	1.234	1.224	EPSD	CCLE	1.204	Down-regulation
AGC_PKC_PKCd_PRKCQ_ST	P35568	IRS1	Q04759	PRKCQ	T305	R302Q	302	Missense	distal	-3	no	1.234	0.006	EPSD	CCLE	1.204	Loss
AGC_PKC_PKCd_PRKCQ_ST	P35568	IRS1	Q04759	PRKCQ	S307	A314D	314	Missense	distal	7	no	1.791	1.824	EPSD	CCLE	1.204	Up-regulation
AGC_PKC_PKCd_PRKCQ_ST	P35568	IRS1	Q04759	PRKCQ	S307	R304H	304	Missense	distal	-3	no	1.791	0.678	EPSD	CCLE	1.204	Loss
AGC_PKC_PKCd_PRKCQ_ST	P35568	IRS1	Q04759	PRKCQ	S307	R302Q	302	Missense	distal	-5	no	1.791	1.555	EPSD	CCLE	1.204	Down-regulation
AGC_PKC_PKCd_PRKCQ_ST	P35568	IRS1	Q04759	PRKCQ	T525	P532S	532	Missense	distal	7	no	1.703	1.709	EPSD	CCLE	1.204	Up-regulation
AGC_PKC_PKCd_PRKCQ_ST	P35568	IRS1	Q04759	PRKCQ	S527	P532S	532	Missense	distal	5	no	1.950	1.947	EPSD	CCLE	1.204	Down-regulation
AGC_PKC_PKCd_PRKCQ_ST	P35568	IRS1	Q04759	PRKCQ	S574	T579I	579	Missense	distal	5	no	1.323	1.324	EPSD	CCLE	1.204	Up-regulation
AGC_PKC_PKCd_PRKCQ_ST	P35568	IRS1	Q04759	PRKCQ	S574	V577M	577	Missense	distal	3	no	1.323	1.331	EPSD	CCLE	1.204	Up-regulation
AGC_PKC_PKCd_PRKCQ_ST	P35568	IRS1	Q04759	PRKCQ	S792	S795Y	795	Missense	distal	3	no	1.315	1.307	EPSD	CCLE	1.204	Down-regulation
AGC_PKC_PKCd_PRKCQ_ST	P35568	IRS1	Q04759	PRKCQ	S792	L791P	791	Missense	proximal	-1	no	1.315	1.318	EPSD	CCLE	1.204	Up-regulation
AGC_PKC_PKCd_PRKCQ_ST	P35568	IRS1	Q04759	PRKCQ	T793	L791P	791	Missense	proximal	-2	no	1.021	1.236	EPSD	CCLE	1.204	Gain
AGC_PKC_PKCd_PRKCQ_ST	P35568	IRS1	Q04759	PRKCQ	S1100	S1105F	1105	Missense	distal	5	no	2.727	2.725	EPSD	CCLE	1.204	Down-regulation
AGC_PKC_PKCd_PRKCQ_ST	P35568	IRS1	Q04759	PRKCQ	S1101	S1105F	1105	Missense	distal	4	no	2.483	2.482	PhosphoSitePlus	CCLE	1.204	Down-regulation
AGC_PKC_PKCd_PRKCQ_ST	P35568	IRS1	Q04759	PRKCQ	S1142	E1136K	1136	Missense	distal	-6	no	2.325	2.173	EPSD	CCLE	1.204	Down-regulation
AGC_PKC_PKCd_PRKCQ_ST	P35568	IRS1	Q04759	PRKCQ	S1143	E1136K	1136	Missense	distal	-7	no	2.131	2.113	EPSD	CCLE	1.204	Down-regulation
AGC_PKC_PKCd_PRKCQ_ST	P35236	PTPN7	Q04759	PRKCQ	T71	E69K	69	Missense	proximal	-2	no	0.859	1.398	EPSD	CCLE	1.204	Gain
AGC_PKC_PKCd_PRKCQ_ST	P35236	PTPN7	Q04759	PRKCQ	S106	E99K	99	Missense	distal	-7	no	1.445	1.428	EPSD	CCLE	1.204	Down-regulation
AGC_PKC_PKCd_PRKCQ_ST	P35236	PTPN7	Q04759	PRKCQ	S143	G147R	147	Missense	distal	4	no	1.503	1.687	EPSD	CCLE	1.204	Up-regulation
AGC_PKC_PKCd_PRKCQ_ST	Q3V6T2	CCDC88A	Q04759	PRKCQ	S230	P234S	234	Missense	distal	4	no	1.221	1.208	EPSD	CCLE	1.204	Down-regulation
AGC_PKC_PKCd_PRKCQ_ST	Q3V6T2	CCDC88A	Q04759	PRKCQ	S1417	P1422R	1422	Missense	distal	5	no	1.768	1.789	EPSD	CCLE	1.204	Up-regulation
AGC_PKC_PKCd_PRKCQ_ST	Q3V6T2	CCDC88A	Q04759	PRKCQ	S1417	S1417Y	1417	Missense	central	0	yes	1.768	0.000	EPSD	CCLE	1.204	Loss
AGC_PKC_PKCd_PRKCQ_ST	Q3V6T2	CCDC88A	Q04759	PRKCQ	S1425	P1422R	1422	Missense	distal	-3	no	0.949	1.935	EPSD	CCLE	1.204	Gain
AGC_PKC_PKCd_PRKCQ_ST	Q3V6T2	CCDC88A	Q04759	PRKCQ	S1427	P1422R	1422	Missense	distal	-5	no	2.116	2.308	EPSD	CCLE	1.204	Up-regulation
AGC_PKC_PKCd_PRKCQ_ST	Q3V6T2	CCDC88A	Q04759	PRKCQ	S1491	R1488C	1488	Missense	distal	-3	no	1.838	0.538	EPSD	CCLE	1.204	Loss
AGC_PKC_PKCd_PRKCQ_ST	O95267	RASGRP1	Q04759	PRKCQ	T184	R181K	181	Missense	distal	-3	no	1.751	1.333	PhosphoSitePlus	CCLE	1.204	Down-regulation
AGC_PKC_PKCd_PRKCQ_ST	O95267	RASGRP1	Q04759	PRKCQ	S732	K730E	730	Missense	proximal	-2	no	1.220	0.680	EPSD	CCLE	1.204	Loss
AGC_PKC_PKCd_PRKCQ_ST	Q9BXL7	CARD11	Q04759	PRKCQ	S559	E566G	566	Missense	distal	7	no	1.890	1.895	PhosphoSitePlus	CCLE	1.204	Up-regulation
AGC_PKC_PKCd_PRKCQ_ST	Q9BXL7	CARD11	Q04759	PRKCQ	S559	S558T	558	Missense	proximal	-1	no	1.890	1.885	PhosphoSitePlus	CCLE	1.204	Down-regulation
AGC_PKC_PKCd_PRKCQ_ST	P10588	NR2F6	Q04759	PRKCQ	S83	F79L	79	Missense	distal	-4	no	1.324	1.314	PhosphoSitePlus	CCLE	1.204	Down-regulation
AGC_PKC_PKCd_PRKCQ_ST	P10588	NR2F6	Q04759	PRKCQ	S89	I84T	84	Missense	distal	-5	no	2.271	2.274	EPSD	CCLE	1.204	Up-regulation
AGC_PKC_PKCd_PRKCQ_ST	P26038	MSN	Q04759	PRKCQ	S6	D13Y	13	Missense	distal	7	no	1.727	1.715	EPSD	CCLE	1.204	Down-regulation
AGC_PKC_PKCd_PRKCQ_ST	P26038	MSN	Q04759	PRKCQ	S384	K391E	391	Missense	distal	7	no	2.355	2.404	EPSD	CCLE	1.204	Up-regulation
AGC_PKC_PKCd_PRKCQ_ST	O43516	WIPF1	Q04759	PRKCQ	S142	R149M	149	Missense	distal	7	no	1.664	1.746	EPSD	CCLE	1.204	Up-regulation
AGC_PKC_PKCd_PRKCQ_ST	O43516	WIPF1	Q04759	PRKCQ	S340	P335Q	335	Missense	distal	-5	no	1.634	1.590	EPSD	CCLE	1.204	Down-regulation
AGC_PKC_PKCd_PRKCQ_ST	O43516	WIPF1	Q04759	PRKCQ	S424	A427V	427	Missense	distal	3	no	1.282	1.274	EPSD	CCLE	1.204	Down-regulation
AGC_PKC_PKCd_PRKCQ_ST	O43516	WIPF1	Q04759	PRKCQ	S434	A427V	427	Missense	distal	-7	no	1.313	1.319	EPSD	CCLE	1.204	Up-regulation
AGC_PKC_PKCd_PRKCQ_ST	Q9Y4G8	RAPGEF2	Q04759	PRKCQ	S1089	S1089F	1089	Missense	central	0	yes	1.308	0.000	EPSD	CCLE	1.204	Loss
AGC_PKC_PKCd_PRKCQ_ST	Q9Y4G8	RAPGEF2	Q04759	PRKCQ	S1176	R1172G	1172	Missense	distal	-4	no	1.864	1.806	EPSD	CCLE	1.204	Down-regulation
AGC_PKC_PKCd_PRKCQ_ST	Q13191	CBLB	Q04759	PRKCQ	S656	S656Y	656	Missense	central	0	yes	1.350	0.000	EPSD	CCLE	1.204	Loss
AGC_PKC_PKCd_PRKCQ_ST	Q13191	CBLB	Q04759	PRKCQ	S793	D787N	787	Missense	distal	-6	no	1.494	1.458	EPSD	CCLE	1.204	Down-regulation
AGC_PKC_PKCd_PRKCQ_ST	Q5JVS0	HABP4	Q04759	PRKCQ	S108	S108N	108	Missense	central	0	yes	2.255	0.000	EPSD	CCLE	1.204	Loss
AGC_PKC_PKCd_PRKCQ_ST	O14974	PPP1R12A	Q04759	PRKCQ	S472	S477A	477	Missense	distal	5	no	1.692	1.694	EPSD	CCLE	1.204	Up-regulation
AGC_PKC_PKCd_PRKCQ_ST	O14974	PPP1R12A	Q04759	PRKCQ	S477	S477A	477	Missense	central	0	yes	1.608	0.000	EPSD	CCLE	1.204	Loss
AGC_PKC_PKCd_PRKCQ_ST	O14974	PPP1R12A	Q04759	PRKCQ	S478	S477A	477	Missense	proximal	-1	no	1.328	1.326	EPSD	CCLE	1.204	Down-regulation
AGC_PKC_PKCd_PRKCQ_ST	O14974	PPP1R12A	Q04759	PRKCQ	S520	D518E	518	Missense	proximal	-2	no	1.331	1.301	EPSD	CCLE	1.204	Down-regulation
AGC_PKC_PKCd_PRKCQ_ST	Q15052	ARHGEF6	Q04759	PRKCQ	S640	V645A	645	Missense	distal	5	no	1.823	1.833	EPSD	CCLE	1.204	Up-regulation
AGC_PKC_PKCd_PRKCQ_ST	Q15052	ARHGEF6	Q04759	PRKCQ	S649	V645A	645	Missense	distal	-4	no	1.243	1.264	EPSD	CCLE	1.204	Up-regulation
AGC_PKC_PKCd_PRKCQ_ST	Q8IV61	RASGRP3	Q04759	PRKCQ	S385	P392S	392	Missense	distal	7	no	1.489	1.494	EPSD	CCLE	1.204	Up-regulation
AGC_PKC_PKCd_PRKCQ_ST	Q8IV61	RASGRP3	Q04759	PRKCQ	S638	M636L	636	Missense	proximal	-2	no	1.681	1.552	EPSD	CCLE	1.204	Down-regulation
AGC_PKA_PRKACB_ST	Q01130	SRSF2	P22694	PRKACB	S121	R118G	118	Missense	distal	-3	no	3.788	1.645	PhosphoSitePlus;EPSD	CCLE	2.323	Loss
CK1_CK1_CK1-G_CSNK1G1_ST	P25054	APC	Q9HCP0	CSNK1G1	S559	V566I	566	Missense	distal	7	no	2.048	2.045	EPSD	CCLE	1.928	Down-regulation
CK1_CK1_CK1-G_CSNK1G1_ST	P25054	APC	Q9HCP0	CSNK1G1	T867	P865L	865	Missense	proximal	-2	no	1.988	2.040	EPSD	CCLE	1.928	Up-regulation
CK1_CK1_CK1-G_CSNK1G1_ST	P25054	APC	Q9HCP0	CSNK1G1	S1180	V1173M	1173	Missense	distal	-7	no	2.050	2.105	EPSD	CCLE	1.928	Up-regulation
CK1_CK1_CK1-G_CSNK1G1_ST	P25054	APC	Q9HCP0	CSNK1G1	T1655	T1661K	1661	Missense	distal	6	no	2.326	2.414	EPSD	CCLE	1.928	Up-regulation
CK1_CK1_CK1-G_CSNK1G1_ST	P25054	APC	Q9HCP0	CSNK1G1	S1658	T1661K	1661	Missense	distal	3	no	2.003	1.967	EPSD	CCLE	1.928	Down-regulation
CK1_CK1_CK1-G_CSNK1G1_ST	P25054	APC	Q9HCP0	CSNK1G1	T1661	T1661K	1661	Missense	central	0	yes	2.545	0.000	EPSD	CCLE	1.928	Loss
CK1_CK1_CK1-G_CSNK1G1_ST	P25054	APC	Q9HCP0	CSNK1G1	S2034	D2033E	2033	Missense	proximal	-1	no	2.197	2.111	EPSD	CCLE	1.928	Down-regulation
CK1_CK1_CK1-G_CSNK1G1_ST	P25054	APC	Q9HCP0	CSNK1G1	S2349	L2345I	2345	Missense	distal	-4	no	1.975	1.958	EPSD	CCLE	1.928	Down-regulation
CK1_CK1_CK1-G_CSNK1G1_ST	P25054	APC	Q9HCP0	CSNK1G1	S2359	S2361F	2361	Missense	proximal	2	no	2.784	2.945	EPSD	CCLE	1.928	Up-regulation
CK1_CK1_CK1-G_CSNK1G1_ST	P25054	APC	Q9HCP0	CSNK1G1	S2627	F2620C	2620	Missense	distal	-7	no	2.082	2.186	EPSD	CCLE	1.928	Up-regulation
CK1_CK1_CK1-G_CSNK1G1_ST	P25054	APC	Q9HCP0	CSNK1G1	S2766	S2768R	2768	Missense	proximal	2	no	1.902	2.038	EPSD	CCLE	1.928	Gain
CK1_CK1_CK1-G_CSNK1G1_ST	Q04206	RELA	Q9HCP0	CSNK1G1	S468	A467V	467	Missense	proximal	-1	no	2.623	2.642	EPSD	CCLE	1.928	Up-regulation
CK1_CK1_CK1-G_CSNK1G1_ST	Q04206	RELA	Q9HCP0	CSNK1G1	S472	A467V	467	Missense	distal	-5	no	2.443	2.434	EPSD	CCLE	1.928	Down-regulation
CK1_CK1_CK1-G_CSNK1G1_ST	Q04206	RELA	Q9HCP0	CSNK1G1	S536	S535A	535	Missense	proximal	-1	no	3.108	3.013	PhosphoSitePlus	CCLE	1.928	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	P12931	SRC	O14757	CHEK1	S12	L18R	18	Missense	distal	6	no	8.908	8.586	EPSD	CCLE	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	P12931	SRC	O14757	CHEK1	S17	L18R	18	Missense	proximal	1	no	9.633	9.668	EPSD	CCLE	5.604	Up-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	P12931	SRC	O14757	CHEK1	S43	T37P	37	Missense	distal	-6	no	5.985	6.013	EPSD	CCLE	5.604	Up-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q6PD62	CTR9	O14757	CHEK1	T263	P269L	269	Missense	distal	6	no	12.864	12.654	EPSD	CCLE	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	P11047	LAMC1	O14757	CHEK1	S1552	V1551G	1551	Missense	proximal	-1	no	6.723	6.646	EPSD	CCLE	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q9NUU7	DDX19A	O14757	CHEK1	S92	R97Q	97	Missense	distal	5	no	7.232	7.307	PhosphoSitePlus	CCLE	5.604	Up-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	P84098	RPL19	O14757	CHEK1	T56	A61S	61	Missense	distal	5	no	5.624	5.605	PhosphoSitePlus;EPSD	CCLE	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	P84098	RPL19	O14757	CHEK1	T67	A61S	61	Missense	distal	-6	no	10.349	10.475	EPSD	CCLE	5.604	Up-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	P84098	RPL19	O14757	CHEK1	T67	K65R	65	Missense	proximal	-2	no	10.349	10.530	EPSD	CCLE	5.604	Up-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	P67809	YBX1	O14757	CHEK1	T80	F85C	85	Missense	distal	5	no	12.148	12.126	PhosphoSitePlus	CCLE	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q7Z2Z1	TICRR	O14757	CHEK1	S599	P600S	600	Missense	proximal	1	no	5.599	5.636	EPSD	CCLE	5.604	Gain
CAMK_CAMKL_CHK1_CHEK1_ST	Q7Z2Z1	TICRR	O14757	CHEK1	S891	P893S	893	Missense	proximal	2	no	7.297	7.374	EPSD	CCLE	5.604	Up-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q7Z2Z1	TICRR	O14757	CHEK1	S1224	E1221K	1221	Missense	distal	-3	no	6.096	9.359	EPSD	CCLE	5.604	Up-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q7Z2Z1	TICRR	O14757	CHEK1	S1452	W1449R	1449	Missense	distal	-3	no	-24.878	8.725	EPSD	CCLE	5.604	Gain
CAMK_CAMKL_CHK1_CHEK1_ST	Q7Z2Z1	TICRR	O14757	CHEK1	S1806	G1805R	1805	Missense	proximal	-1	no	6.466	6.449	EPSD	CCLE	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q7Z2Z1	TICRR	O14757	CHEK1	S1808	G1805R	1805	Missense	distal	-3	no	4.888	12.662	EPSD	CCLE	5.604	Gain
CAMK_CAMKL_CHK1_CHEK1_ST	Q9NRL2	BAZ1A	O14757	CHEK1	S960	T954A	954	Missense	distal	-6	no	9.431	9.235	EPSD	CCLE	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q9NRL2	BAZ1A	O14757	CHEK1	S1426	G1422C	1422	Missense	distal	-4	no	10.205	9.805	EPSD	CCLE	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	P54132	BLM	O14757	CHEK1	S42	N46S	46	Missense	distal	4	no	6.851	6.831	EPSD	CCLE	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	P54132	BLM	O14757	CHEK1	T412	T412M	412	Missense	central	0	yes	6.894	0.000	EPSD	CCLE	5.604	Loss
CAMK_CAMKL_CHK1_CHEK1_ST	P54132	BLM	O14757	CHEK1	S539	N541Y	541	Missense	proximal	2	no	8.908	8.429	PhosphoSitePlus;EPSD	CCLE	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	P54132	BLM	O14757	CHEK1	S539	R545S	545	Missense	distal	6	no	8.908	8.820	PhosphoSitePlus;EPSD	CCLE	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	P54132	BLM	O14757	CHEK1	S1128	G1129R	1129	Missense	proximal	1	no	8.259	8.267	EPSD	CCLE	5.604	Up-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	O00716	E2F3	O14757	CHEK1	S124	G126S	126	Missense	proximal	2	no	12.407	12.472	PhosphoSitePlus	CCLE	5.604	Up-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	O14757	CHEK1	O14757	CHEK1	S280	A273T	273	Missense	distal	-7	no	10.080	8.763	EPSD	CCLE	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	O14757	CHEK1	O14757	CHEK1	S280	T279A	279	Missense	proximal	-1	no	10.080	10.208	EPSD	CCLE	5.604	Up-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q14669	TRIP12	O14757	CHEK1	T54	D50N	50	Missense	distal	-4	no	8.431	8.355	EPSD	CCLE	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q14669	TRIP12	O14757	CHEK1	S77	P78S	78	Missense	proximal	1	no	8.888	8.925	EPSD	CCLE	5.604	Up-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q14669	TRIP12	O14757	CHEK1	S85	P78S	78	Missense	distal	-7	no	7.771	8.441	EPSD	CCLE	5.604	Up-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q14669	TRIP12	O14757	CHEK1	S109	S109N	109	Missense	central	0	yes	5.781	0.000	EPSD	CCLE	5.604	Loss
CAMK_CAMKL_CHK1_CHEK1_ST	Q14669	TRIP12	O14757	CHEK1	S312	S319G	319	Missense	distal	7	no	7.808	7.907	EPSD	CCLE	5.604	Up-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	P85299	PRR5	O14757	CHEK1	S11	R5C	5	Missense	distal	-6	no	5.730	5.846	EPSD	CCLE	5.604	Up-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	P85299	PRR5	O14757	CHEK1	S11	F9L	9	Missense	proximal	-2	no	5.730	5.545	EPSD	CCLE	5.604	Loss
CAMK_CAMKL_CHK1_CHEK1_ST	O15350	TP73	O14757	CHEK1	S426	P425L	425	Missense	proximal	-1	no	6.018	5.831	EPSD	CCLE	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q12789	GTF3C1	O14757	CHEK1	S480	S486R	486	Missense	distal	6	no	6.209	6.297	EPSD	CCLE	5.604	Up-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q12789	GTF3C1	O14757	CHEK1	S695	H693Y	693	Missense	proximal	-2	no	7.572	7.520	EPSD	CCLE	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q12789	GTF3C1	O14757	CHEK1	S1767	S1767L	1767	Missense	central	0	yes	13.121	0.000	EPSD	CCLE	5.604	Loss
CAMK_CAMKL_CHK1_CHEK1_ST	Q12789	GTF3C1	O14757	CHEK1	S1842	E1848D	1848	Missense	distal	6	no	7.120	7.206	EPSD	CCLE	5.604	Up-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q12789	GTF3C1	O14757	CHEK1	S1865	E1869D	1869	Missense	distal	4	no	10.048	10.140	EPSD	CCLE	5.604	Up-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	P16989	YBX3	O14757	CHEK1	S217	A219F	219	Missense	proximal	2	no	9.466	8.866	EPSD	CCLE	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	P16989	YBX3	O14757	CHEK1	S217	S217F	217	Missense	central	0	yes	9.466	0.000	EPSD	CCLE	5.604	Loss
CAMK_CAMKL_CHK1_CHEK1_ST	P30304	CDC25A	O14757	CHEK1	S178	Q174H	174	Missense	distal	-4	no	11.553	11.196	EPSD;PhosphoSitePlus	CCLE	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	P30304	CDC25A	O14757	CHEK1	S505	R506W	506	Missense	proximal	1	no	7.469	7.439	EPSD	CCLE	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	P30304	CDC25A	O14757	CHEK1	S505	L498P	498	Missense	distal	-7	no	7.469	7.683	EPSD	CCLE	5.604	Up-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	P30304	CDC25A	O14757	CHEK1	T507	R506W	506	Missense	proximal	-1	no	6.453	6.570	EPSD;PhosphoSitePlus	CCLE	5.604	Up-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	P46013	MKI67	O14757	CHEK1	S507	G510V	510	Missense	distal	3	no	9.465	9.891	EPSD	CCLE	5.604	Up-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	P46013	MKI67	O14757	CHEK1	S563	E562A	562	Missense	proximal	-1	no	6.510	6.772	EPSD	CCLE	5.604	Up-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	P46013	MKI67	O14757	CHEK1	S1533	S1533L	1533	Missense	central	0	yes	12.861	0.000	EPSD	CCLE	5.604	Loss
CAMK_CAMKL_CHK1_CHEK1_ST	P46013	MKI67	O14757	CHEK1	S1533	T1531A	1531	Missense	proximal	-2	no	12.861	12.722	EPSD	CCLE	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	P46013	MKI67	O14757	CHEK1	T1764	A1762V	1762	Missense	proximal	-2	no	9.501	9.578	PhosphoSitePlus	CCLE	5.604	Up-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	P46013	MKI67	O14757	CHEK1	S2261	R2258P	2258	Missense	distal	-3	no	13.599	6.463	EPSD	CCLE	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	P46013	MKI67	O14757	CHEK1	S2920	L2918P	2918	Missense	proximal	-2	no	5.683	5.862	EPSD	CCLE	5.604	Up-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	P46013	MKI67	O14757	CHEK1	S3041	M3048I	3048	Missense	distal	7	no	11.028	10.751	EPSD	CCLE	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	P46013	MKI67	O14757	CHEK1	S3249	V3242I	3242	Missense	distal	-7	no	8.179	7.742	EPSD	CCLE	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q9UJM3	ERRFI1	O14757	CHEK1	S302	S307P	307	Missense	distal	5	no	10.251	10.170	PhosphoSitePlus;EPSD	CCLE	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q9UJM3	ERRFI1	O14757	CHEK1	S334	P327L	327	Missense	distal	-7	no	8.988	8.773	EPSD	CCLE	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q9BXW9	FANCD2	O14757	CHEK1	S88	P87L	87	Missense	proximal	-1	no	11.390	11.204	EPSD	CCLE	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q9UKM9	RALY	O14757	CHEK1	S106	I108M	108	Missense	proximal	2	no	14.696	15.275	EPSD	CCLE	5.604	Up-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q12888	TP53BP1	O14757	CHEK1	S265	M262R	262	Missense	distal	-3	no	1.876	7.024	EPSD	CCLE	5.604	Gain
CAMK_CAMKL_CHK1_CHEK1_ST	Q12888	TP53BP1	O14757	CHEK1	T1270	T1270I	1270	Missense	central	0	yes	8.486	0.000	EPSD	CCLE	5.604	Loss
CAMK_CAMKL_CHK1_CHEK1_ST	Q12888	TP53BP1	O14757	CHEK1	S1631	V1633I	1633	Missense	proximal	2	no	8.527	8.127	EPSD	CCLE	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q14966	ZNF638	O14757	CHEK1	S500	R506C	506	Missense	distal	6	no	9.280	9.574	EPSD	CCLE	5.604	Up-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q14966	ZNF638	O14757	CHEK1	S501	R506C	506	Missense	distal	5	no	9.081	8.837	EPSD	CCLE	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q14966	ZNF638	O14757	CHEK1	S510	R506C	506	Missense	distal	-4	no	9.474	9.100	EPSD	CCLE	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q14966	ZNF638	O14757	CHEK1	S520	R521Q	521	Missense	proximal	1	no	6.328	6.337	EPSD	CCLE	5.604	Up-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q14966	ZNF638	O14757	CHEK1	S522	R521Q	521	Missense	proximal	-1	no	7.756	7.771	EPSD	CCLE	5.604	Up-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q14966	ZNF638	O14757	CHEK1	S661	R667L	667	Missense	distal	6	no	5.901	6.222	EPSD	CCLE	5.604	Up-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q14966	ZNF638	O14757	CHEK1	S671	R667L	667	Missense	distal	-4	no	6.735	6.479	EPSD	CCLE	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q14966	ZNF638	O14757	CHEK1	S1468	S1462G	1462	Missense	distal	-6	no	9.304	9.342	EPSD	CCLE	5.604	Up-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q14966	ZNF638	O14757	CHEK1	T1487	T1487R	1487	Missense	central	0	yes	9.382	0.000	EPSD	CCLE	5.604	Loss
CAMK_CAMKL_CHK1_CHEK1_ST	Q14966	ZNF638	O14757	CHEK1	S1823	K1817R	1817	Missense	distal	-6	no	6.539	6.549	EPSD	CCLE	5.604	Up-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q14966	ZNF638	O14757	CHEK1	S1823	E1822K	1822	Missense	proximal	-1	no	6.539	6.481	EPSD	CCLE	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q14966	ZNF638	O14757	CHEK1	S1825	E1822K	1822	Missense	distal	-3	no	4.423	7.686	EPSD	CCLE	5.604	Gain
CAMK_CAMKL_CHK1_CHEK1_ST	Q99590	SCAF11	O14757	CHEK1	S816	P814T	814	Missense	proximal	-2	no	9.655	9.625	EPSD	CCLE	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q99590	SCAF11	O14757	CHEK1	S816	R813Q	813	Missense	distal	-3	no	9.655	2.448	EPSD	CCLE	5.604	Loss
CAMK_CAMKL_CHK1_CHEK1_ST	Q99590	SCAF11	O14757	CHEK1	S902	V898L	898	Missense	distal	-4	no	7.337	7.089	EPSD	CCLE	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q99590	SCAF11	O14757	CHEK1	S1170	M1177V	1177	Missense	distal	7	no	8.243	8.387	EPSD	CCLE	5.604	Up-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q9UQ35	SRRM2	O14757	CHEK1	S248	A254V	254	Missense	distal	6	no	10.348	10.236	EPSD	CCLE	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q9UQ35	SRRM2	O14757	CHEK1	S250	A254V	254	Missense	distal	4	no	7.002	6.919	EPSD	CCLE	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q9UQ35	SRRM2	O14757	CHEK1	T252	A254V	254	Missense	proximal	2	no	7.267	6.704	EPSD	CCLE	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q9UQ35	SRRM2	O14757	CHEK1	T252	R259Q	259	Missense	distal	7	no	7.267	7.422	EPSD	CCLE	5.604	Up-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q9UQ35	SRRM2	O14757	CHEK1	S472	H475D	475	Missense	distal	3	no	4.367	5.897	EPSD	CCLE	5.604	Gain
CAMK_CAMKL_CHK1_CHEK1_ST	Q9UQ35	SRRM2	O14757	CHEK1	T476	H473R	473	Missense	distal	-3	no	2.994	8.804	EPSD	CCLE	5.604	Gain
CAMK_CAMKL_CHK1_CHEK1_ST	Q9UQ35	SRRM2	O14757	CHEK1	S564	R570K	570	Missense	distal	6	no	10.230	10.142	EPSD	CCLE	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q9UQ35	SRRM2	O14757	CHEK1	S573	R570K	570	Missense	distal	-3	no	7.570	3.745	EPSD	CCLE	5.604	Loss
CAMK_CAMKL_CHK1_CHEK1_ST	Q9UQ35	SRRM2	O14757	CHEK1	S575	R570K	570	Missense	distal	-5	no	11.312	12.487	EPSD	CCLE	5.604	Up-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q9UQ35	SRRM2	O14757	CHEK1	T577	R570K	570	Missense	distal	-7	no	10.330	11.510	EPSD	CCLE	5.604	Up-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q9UQ35	SRRM2	O14757	CHEK1	S625	R628Q	628	Missense	distal	3	no	10.749	11.811	EPSD	CCLE	5.604	Up-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q9UQ35	SRRM2	O14757	CHEK1	T627	R628Q	628	Missense	proximal	1	no	8.793	8.802	EPSD	CCLE	5.604	Up-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q9UQ35	SRRM2	O14757	CHEK1	S629	R628Q	628	Missense	proximal	-1	no	9.936	9.951	EPSD	CCLE	5.604	Up-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q9UQ35	SRRM2	O14757	CHEK1	S629	S635P	635	Missense	distal	6	no	9.936	10.555	EPSD	CCLE	5.604	Up-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q9UQ35	SRRM2	O14757	CHEK1	S635	R628Q	628	Missense	distal	-7	no	9.654	9.912	EPSD	CCLE	5.604	Up-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q9UQ35	SRRM2	O14757	CHEK1	S635	S635P	635	Missense	central	0	yes	9.654	0.000	EPSD	CCLE	5.604	Loss
CAMK_CAMKL_CHK1_CHEK1_ST	Q9UQ35	SRRM2	O14757	CHEK1	S637	S635P	635	Missense	proximal	-2	no	11.078	11.362	EPSD	CCLE	5.604	Up-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q9UQ35	SRRM2	O14757	CHEK1	S637	S644N	644	Missense	distal	7	no	11.078	11.307	EPSD	CCLE	5.604	Up-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q9UQ35	SRRM2	O14757	CHEK1	S639	S635P	635	Missense	distal	-4	no	10.214	10.450	EPSD	CCLE	5.604	Up-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q9UQ35	SRRM2	O14757	CHEK1	S639	S644N	644	Missense	distal	5	no	10.214	10.212	EPSD	CCLE	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q9UQ35	SRRM2	O14757	CHEK1	S644	S644N	644	Missense	central	0	yes	6.073	0.000	EPSD	CCLE	5.604	Loss
CAMK_CAMKL_CHK1_CHEK1_ST	Q9UQ35	SRRM2	O14757	CHEK1	S649	S644N	644	Missense	distal	-5	no	8.534	9.027	EPSD	CCLE	5.604	Up-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q9UQ35	SRRM2	O14757	CHEK1	T651	S644N	644	Missense	distal	-7	no	9.375	8.837	EPSD	CCLE	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q9UQ35	SRRM2	O14757	CHEK1	S929	P936S	936	Missense	distal	7	no	8.316	8.261	EPSD	CCLE	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q9UQ35	SRRM2	O14757	CHEK1	S1140	D1141V	1141	Missense	proximal	1	no	6.166	6.055	EPSD	CCLE	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q9UQ35	SRRM2	O14757	CHEK1	S1497	P1490S	1490	Missense	distal	-7	no	7.995	8.665	EPSD;PhosphoSitePlus	CCLE	5.604	Up-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q9UQ35	SRRM2	O14757	CHEK1	S1559	S1561Y	1561	Missense	proximal	2	no	7.111	6.814	EPSD	CCLE	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q9UQ35	SRRM2	O14757	CHEK1	S1638	K1643E	1643	Missense	distal	5	no	7.683	7.748	EPSD	CCLE	5.604	Up-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q9UQ35	SRRM2	O14757	CHEK1	S1640	K1643E	1643	Missense	distal	3	no	7.474	8.290	EPSD	CCLE	5.604	Up-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q9UQ35	SRRM2	O14757	CHEK1	S1648	K1643E	1643	Missense	distal	-5	no	12.260	9.698	EPSD	CCLE	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q9UQ35	SRRM2	O14757	CHEK1	S1690	S1694F	1694	Missense	distal	4	no	6.896	6.994	EPSD	CCLE	5.604	Up-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q9UQ35	SRRM2	O14757	CHEK1	S1691	S1694F	1694	Missense	distal	3	no	5.807	5.995	EPSD	CCLE	5.604	Up-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q9UQ35	SRRM2	O14757	CHEK1	S1729	P1728S	1728	Missense	proximal	-1	no	6.212	5.765	EPSD	CCLE	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q9UQ35	SRRM2	O14757	CHEK1	S1747	R1744G	1744	Missense	distal	-3	no	10.408	2.633	EPSD	CCLE	5.604	Loss
CAMK_CAMKL_CHK1_CHEK1_ST	Q9UQ35	SRRM2	O14757	CHEK1	S1749	R1744G	1744	Missense	distal	-5	no	11.554	11.388	EPSD	CCLE	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q9UQ35	SRRM2	O14757	CHEK1	S1762	R1759T	1759	Missense	distal	-3	no	7.307	-13.262	EPSD	CCLE	5.604	Loss
CAMK_CAMKL_CHK1_CHEK1_ST	Q9UQ35	SRRM2	O14757	CHEK1	S1764	R1759T	1759	Missense	distal	-5	no	10.026	10.947	EPSD	CCLE	5.604	Up-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q9UQ35	SRRM2	O14757	CHEK1	S1972	R1979H	1979	Missense	distal	7	no	9.850	9.557	EPSD	CCLE	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q9UQ35	SRRM2	O14757	CHEK1	T1974	R1979H	1979	Missense	distal	5	no	8.174	8.190	EPSD	CCLE	5.604	Up-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q9UQ35	SRRM2	O14757	CHEK1	S1982	R1979H	1979	Missense	distal	-3	no	11.918	6.108	EPSD	CCLE	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q9UQ35	SRRM2	O14757	CHEK1	S1982	S1984F	1984	Missense	proximal	2	no	11.918	11.773	EPSD	CCLE	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q9UQ35	SRRM2	O14757	CHEK1	S1984	R1979H	1979	Missense	distal	-5	no	9.464	6.999	EPSD	CCLE	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q9UQ35	SRRM2	O14757	CHEK1	S1984	S1984F	1984	Missense	central	0	yes	9.464	0.000	EPSD	CCLE	5.604	Loss
CAMK_CAMKL_CHK1_CHEK1_ST	Q9UQ35	SRRM2	O14757	CHEK1	T1986	R1979H	1979	Missense	distal	-7	no	8.766	8.707	EPSD	CCLE	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q9UQ35	SRRM2	O14757	CHEK1	T1986	S1984F	1984	Missense	proximal	-2	no	8.766	9.056	EPSD	CCLE	5.604	Up-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q9UQ35	SRRM2	O14757	CHEK1	S1996	R2003Q	2003	Missense	distal	7	no	9.955	10.110	EPSD	CCLE	5.604	Up-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q9UQ35	SRRM2	O14757	CHEK1	T1998	R2003Q	2003	Missense	distal	5	no	8.160	8.235	EPSD	CCLE	5.604	Up-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q9UQ35	SRRM2	O14757	CHEK1	S2006	R2003Q	2003	Missense	distal	-3	no	11.305	4.098	EPSD	CCLE	5.604	Loss
CAMK_CAMKL_CHK1_CHEK1_ST	Q9UQ35	SRRM2	O14757	CHEK1	S2008	R2003Q	2003	Missense	distal	-5	no	10.311	9.915	EPSD	CCLE	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q9UQ35	SRRM2	O14757	CHEK1	T2010	R2003Q	2003	Missense	distal	-7	no	7.039	7.297	EPSD	CCLE	5.604	Up-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q9UQ35	SRRM2	O14757	CHEK1	S2030	P2035Q	2035	Missense	distal	5	no	8.049	8.103	EPSD	CCLE	5.604	Up-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q9UQ35	SRRM2	O14757	CHEK1	S2032	P2035Q	2035	Missense	distal	3	no	12.257	12.987	EPSD	CCLE	5.604	Up-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q9UQ35	SRRM2	O14757	CHEK1	T2034	P2035Q	2035	Missense	proximal	1	no	6.689	6.760	EPSD	CCLE	5.604	Up-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q9UQ35	SRRM2	O14757	CHEK1	S2042	P2035Q	2035	Missense	distal	-7	no	12.881	13.549	EPSD	CCLE	5.604	Up-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q9UQ35	SRRM2	O14757	CHEK1	T2261	R2260Q	2260	Missense	proximal	-1	no	5.910	5.926	EPSD	CCLE	5.604	Up-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q9UQ35	SRRM2	O14757	CHEK1	T2467	A2464G	2464	Missense	distal	-3	no	5.883	4.820	EPSD	CCLE	5.604	Loss
CAMK_CAMKL_CHK1_CHEK1_ST	Q9UQ35	SRRM2	O14757	CHEK1	S2727	R2728C	2728	Missense	proximal	1	no	8.884	8.874	EPSD	CCLE	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q9UQ35	SRRM2	O14757	CHEK1	S2727	H2732Q	2732	Missense	distal	5	no	8.884	8.944	EPSD	CCLE	5.604	Up-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q9UQ35	SRRM2	O14757	CHEK1	S2731	R2728C	2728	Missense	distal	-3	no	6.012	-2.079	EPSD	CCLE	5.604	Loss
CAMK_CAMKL_CHK1_CHEK1_ST	Q9UQ35	SRRM2	O14757	CHEK1	S2731	H2732Q	2732	Missense	proximal	1	no	6.012	6.086	EPSD	CCLE	5.604	Up-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q9UQ35	SRRM2	O14757	CHEK1	T2738	H2732Q	2732	Missense	distal	-6	no	8.671	8.643	EPSD	CCLE	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q9P2D1	CHD7	O14757	CHEK1	S417	V413L	413	Missense	distal	-4	no	9.414	9.166	EPSD	CCLE	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q9P2D1	CHD7	O14757	CHEK1	S417	I420M	420	Missense	distal	3	no	9.414	9.702	EPSD	CCLE	5.604	Up-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q9P2D1	CHD7	O14757	CHEK1	T689	A688V	688	Missense	proximal	-1	no	7.870	7.792	EPSD	CCLE	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q9P2D1	CHD7	O14757	CHEK1	T689	P690S	690	Missense	proximal	1	no	7.870	7.907	EPSD	CCLE	5.604	Up-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q9P2D1	CHD7	O14757	CHEK1	S2255	E2252K	2252	Missense	distal	-3	no	3.312	6.575	EPSD	CCLE	5.604	Gain
CAMK_CAMKL_CHK1_CHEK1_ST	Q9P2D1	CHD7	O14757	CHEK1	T2350	I2346V	2346	Missense	distal	-4	no	6.411	6.691	EPSD	CCLE	5.604	Up-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q9UEY8	ADD3	O14757	CHEK1	S180	T185I	185	Missense	distal	5	no	10.811	10.890	EPSD	CCLE	5.604	Up-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q9UEY8	ADD3	O14757	CHEK1	S402	K397Q	397	Missense	distal	-5	no	12.112	10.541	EPSD	CCLE	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q9UEY8	ADD3	O14757	CHEK1	T651	R648G	648	Missense	distal	-3	no	6.124	-1.651	EPSD	CCLE	5.604	Loss
CAMK_CAMKL_CHK1_CHEK1_ST	P43243	MATR3	O14757	CHEK1	S22	R19H	19	Missense	distal	-3	no	6.427	0.618	EPSD	CCLE	5.604	Loss
CAMK_CAMKL_CHK1_CHEK1_ST	P43243	MATR3	O14757	CHEK1	S54	R51H	51	Missense	distal	-3	no	12.242	6.432	EPSD	CCLE	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	P43243	MATR3	O14757	CHEK1	T150	G153S	153	Missense	distal	3	no	10.156	10.243	EPSD;PhosphoSitePlus	CCLE	5.604	Up-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	P43243	MATR3	O14757	CHEK1	S188	R182G	182	Missense	distal	-6	no	9.262	9.380	EPSD	CCLE	5.604	Up-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	P43243	MATR3	O14757	CHEK1	S307	S302F	302	Missense	distal	-5	no	6.619	6.243	EPSD	CCLE	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	P43243	MATR3	O14757	CHEK1	T396	S397N	397	Missense	proximal	1	no	7.798	7.796	EPSD	CCLE	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	P33992	MCM5	O14757	CHEK1	S605	S600R	600	Missense	distal	-5	no	9.322	9.533	EPSD	CCLE	5.604	Up-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q96T58	SPEN	O14757	CHEK1	S260	P255L	255	Missense	distal	-5	no	8.135	12.842	EPSD	CCLE	5.604	Up-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q96T58	SPEN	O14757	CHEK1	S260	R264K	264	Missense	distal	4	no	8.135	8.037	EPSD	CCLE	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q96T58	SPEN	O14757	CHEK1	S749	A744P	744	Missense	distal	-5	no	7.076	8.286	EPSD	CCLE	5.604	Up-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q96T58	SPEN	O14757	CHEK1	S757	R758Q	758	Missense	proximal	1	no	6.656	6.664	EPSD	CCLE	5.604	Up-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q96T58	SPEN	O14757	CHEK1	S765	R758Q	758	Missense	distal	-7	no	8.886	9.145	EPSD	CCLE	5.604	Up-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q96T58	SPEN	O14757	CHEK1	S830	H829Y	829	Missense	proximal	-1	no	6.492	6.534	EPSD	CCLE	5.604	Up-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q96T58	SPEN	O14757	CHEK1	S832	H829Y	829	Missense	distal	-3	no	6.015	-5.119	EPSD	CCLE	5.604	Loss
CAMK_CAMKL_CHK1_CHEK1_ST	Q96T58	SPEN	O14757	CHEK1	S1082	S1076F	1076	Missense	distal	-6	no	8.936	9.210	EPSD	CCLE	5.604	Up-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q96T58	SPEN	O14757	CHEK1	S1194	P1195S	1195	Missense	proximal	1	no	7.605	7.642	EPSD	CCLE	5.604	Up-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q96T58	SPEN	O14757	CHEK1	S1252	Q1250R	1250	Missense	proximal	-2	no	9.043	8.997	EPSD	CCLE	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q96T58	SPEN	O14757	CHEK1	S1252	G1259C	1259	Missense	distal	7	no	9.043	8.631	EPSD	CCLE	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q96T58	SPEN	O14757	CHEK1	S1306	R1303M	1303	Missense	distal	-3	no	7.820	2.672	EPSD	CCLE	5.604	Loss
CAMK_CAMKL_CHK1_CHEK1_ST	Q96T58	SPEN	O14757	CHEK1	T1502	K1498R	1498	Missense	distal	-4	no	7.571	7.470	EPSD	CCLE	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q96T58	SPEN	O14757	CHEK1	S1504	K1498R	1498	Missense	distal	-6	no	13.048	13.058	EPSD	CCLE	5.604	Up-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q96T58	SPEN	O14757	CHEK1	T1826	T1826A	1826	Missense	central	0	yes	7.038	0.000	EPSD	CCLE	5.604	Loss
CAMK_CAMKL_CHK1_CHEK1_ST	Q96T58	SPEN	O14757	CHEK1	S2305	S2306G	2306	Missense	proximal	1	no	6.146	6.164	EPSD	CCLE	5.604	Up-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q96T58	SPEN	O14757	CHEK1	S2392	T2399A	2399	Missense	distal	7	no	8.135	8.251	EPSD	CCLE	5.604	Up-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q96T58	SPEN	O14757	CHEK1	T3139	Q3135L	3135	Missense	distal	-4	no	6.682	6.266	EPSD	CCLE	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q9NRM7	LATS2	O14757	CHEK1	S380	K383R	383	Missense	distal	3	no	16.516	15.870	EPSD	CCLE	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q9NRM7	LATS2	O14757	CHEK1	S446	E453Q	453	Missense	distal	7	no	6.887	6.801	EPSD	CCLE	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q9NRM7	LATS2	O14757	CHEK1	S446	V449M	449	Missense	distal	3	no	6.887	6.462	EPSD	CCLE	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q9NRM7	LATS2	O14757	CHEK1	S528	Y531H	531	Missense	distal	3	no	11.224	12.479	EPSD	CCLE	5.604	Up-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q9NRM7	LATS2	O14757	CHEK1	S839	D843N	843	Missense	distal	4	no	5.616	5.586	EPSD	CCLE	5.604	Loss
CAMK_CAMKL_CHK1_CHEK1_ST	Q5UIP0	RIF1	O14757	CHEK1	S740	E745G	745	Missense	distal	5	no	7.255	6.979	EPSD	CCLE	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q5UIP0	RIF1	O14757	CHEK1	S1542	S1548G	1548	Missense	distal	6	no	5.816	6.028	EPSD	CCLE	5.604	Up-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q5UIP0	RIF1	O14757	CHEK1	S2224	C2223F	2223	Missense	proximal	-1	no	8.876	8.954	EPSD	CCLE	5.604	Up-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q5UIP0	RIF1	O14757	CHEK1	S2230	C2223F	2223	Missense	distal	-7	no	9.819	9.074	EPSD	CCLE	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q5UIP0	RIF1	O14757	CHEK1	S2401	I2403K	2403	Missense	proximal	2	no	6.579	7.676	EPSD	CCLE	5.604	Up-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q5UIP0	RIF1	O14757	CHEK1	S2465	N2458H	2458	Missense	distal	-7	no	6.321	6.539	EPSD	CCLE	5.604	Up-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q96GD4	AURKB	O14757	CHEK1	T73	D76N	76	Missense	distal	3	no	10.670	9.954	EPSD	CCLE	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q9NXE8	CWC25	O14757	CHEK1	S195	S200N	200	Missense	distal	5	no	9.059	9.057	EPSD	CCLE	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q9NXE8	CWC25	O14757	CHEK1	S195	S193N	193	Missense	proximal	-2	no	9.059	9.248	EPSD	CCLE	5.604	Up-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q9NXE8	CWC25	O14757	CHEK1	S201	S200N	200	Missense	proximal	-1	no	8.239	8.458	EPSD	CCLE	5.604	Up-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q9NXE8	CWC25	O14757	CHEK1	S288	R285G	285	Missense	distal	-3	no	6.871	-0.904	EPSD	CCLE	5.604	Loss
CAMK_CAMKL_CHK1_CHEK1_ST	Q9NXE8	CWC25	O14757	CHEK1	T311	P317L	317	Missense	distal	6	no	10.509	10.299	EPSD	CCLE	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q9NXE8	CWC25	O14757	CHEK1	S318	P317L	317	Missense	proximal	-1	no	9.670	9.483	EPSD	CCLE	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q9NXE8	CWC25	O14757	CHEK1	S337	R343P	343	Missense	distal	6	no	9.505	10.036	PhosphoSitePlus	CCLE	5.604	Up-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q9NXE8	CWC25	O14757	CHEK1	S381	R375M	375	Missense	distal	-6	no	8.534	8.676	EPSD	CCLE	5.604	Up-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q9Y520	PRRC2C	O14757	CHEK1	T826	D831G	831	Missense	distal	5	no	6.156	5.878	EPSD	CCLE	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q9Y520	PRRC2C	O14757	CHEK1	S905	S905P	905	Missense	central	0	yes	7.115	0.000	EPSD	CCLE	5.604	Loss
CAMK_CAMKL_CHK1_CHEK1_ST	Q9Y520	PRRC2C	O14757	CHEK1	S905	E909Q	909	Missense	distal	4	no	7.115	7.207	EPSD	CCLE	5.604	Up-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q9Y520	PRRC2C	O14757	CHEK1	T1215	Y1221H	1221	Missense	distal	6	no	9.178	8.813	EPSD	CCLE	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q9Y520	PRRC2C	O14757	CHEK1	S1242	R1237I	1237	Missense	distal	-5	no	7.926	8.871	EPSD	CCLE	5.604	Up-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q9Y520	PRRC2C	O14757	CHEK1	T1364	A1369D	1369	Missense	distal	5	no	6.899	6.967	EPSD	CCLE	5.604	Up-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q9Y520	PRRC2C	O14757	CHEK1	S1488	P1481Q	1481	Missense	distal	-7	no	5.267	5.936	EPSD	CCLE	5.604	Gain
CAMK_CAMKL_CHK1_CHEK1_ST	Q9Y520	PRRC2C	O14757	CHEK1	S2122	G2118E	2118	Missense	distal	-4	no	9.468	9.645	EPSD	CCLE	5.604	Up-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q9Y520	PRRC2C	O14757	CHEK1	S2665	K2661R	2661	Missense	distal	-4	no	6.843	6.742	EPSD	CCLE	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	P52272	HNRNPM	O14757	CHEK1	S528	M529V	529	Missense	proximal	1	no	6.152	6.160	EPSD	CCLE	5.604	Up-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q15648	MED1	O14757	CHEK1	S256	T262A	262	Missense	distal	6	no	6.456	6.534	EPSD	CCLE	5.604	Up-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q15648	MED1	O14757	CHEK1	S387	R386L	386	Missense	proximal	-1	no	6.340	6.439	EPSD	CCLE	5.604	Up-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q15648	MED1	O14757	CHEK1	S771	D773G	773	Missense	proximal	2	no	7.402	6.871	EPSD	CCLE	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q15648	MED1	O14757	CHEK1	S1417	G1414R	1414	Missense	distal	-3	no	0.984	8.759	EPSD	CCLE	5.604	Gain
CAMK_CAMKL_CHK1_CHEK1_ST	Q9Y2T7	YBX2	O14757	CHEK1	T115	V121I	121	Missense	distal	6	no	11.717	11.484	PhosphoSitePlus	CCLE	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	O95785	WIZ	O14757	CHEK1	S886	R882Q	882	Missense	distal	-4	no	5.688	5.848	EPSD	CCLE	5.604	Up-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	O95785	WIZ	O14757	CHEK1	S1017	S1017P	1017	Missense	central	0	yes	8.348	0.000	EPSD	CCLE	5.604	Loss
CAMK_CAMKL_CHK1_CHEK1_ST	O95785	WIZ	O14757	CHEK1	T1092	S1094Y	1094	Missense	proximal	2	no	5.960	5.663	EPSD	CCLE	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	O95785	WIZ	O14757	CHEK1	S1094	S1094Y	1094	Missense	central	0	yes	10.646	0.000	EPSD	CCLE	5.604	Loss
CAMK_CAMKL_CHK1_CHEK1_ST	P49790	NUP153	O14757	CHEK1	T369	I375V	375	Missense	distal	6	no	7.453	7.686	EPSD	CCLE	5.604	Up-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	P49790	NUP153	O14757	CHEK1	S374	I375V	375	Missense	proximal	1	no	6.002	6.031	EPSD	CCLE	5.604	Up-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	P49790	NUP153	O14757	CHEK1	S660	L656F	656	Missense	distal	-4	no	5.790	5.496	EPSD	CCLE	5.604	Loss
CAMK_CAMKL_CHK1_CHEK1_ST	P49790	NUP153	O14757	CHEK1	T706	S703R	703	Missense	distal	-3	no	-0.856	8.839	EPSD	CCLE	5.604	Gain
CAMK_CAMKL_CHK1_CHEK1_ST	P49790	NUP153	O14757	CHEK1	S1019	S1023G	1023	Missense	distal	4	no	9.747	9.814	EPSD	CCLE	5.604	Up-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q9NWH9	SLTM	O14757	CHEK1	S97	A102S	102	Missense	distal	5	no	5.727	5.709	EPSD	CCLE	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	P10636	MAPT	O14757	CHEK1	S113	G107V	107	Missense	distal	-6	no	5.761	5.736	EPSD	CCLE	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	P10636	MAPT	O14757	CHEK1	T167	E161Q	161	Missense	distal	-6	no	7.796	7.920	EPSD	CCLE	5.604	Up-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	P10636	MAPT	O14757	CHEK1	T167	P170F	170	Missense	distal	3	no	7.796	7.655	EPSD	CCLE	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	P10636	MAPT	O14757	CHEK1	T167	G174A	174	Missense	distal	7	no	7.796	7.747	EPSD	CCLE	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	P10636	MAPT	O14757	CHEK1	S171	G174A	174	Missense	distal	3	no	5.554	5.736	EPSD	CCLE	5.604	Gain
CAMK_CAMKL_CHK1_CHEK1_ST	P10636	MAPT	O14757	CHEK1	S214	D221Y	221	Missense	distal	7	no	12.525	11.620	EPSD	CCLE	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	P10636	MAPT	O14757	CHEK1	T529	R526L	526	Missense	distal	-3	no	6.339	-12.208	EPSD	CCLE	5.604	Loss
CAMK_CAMKL_CHK1_CHEK1_ST	P10636	MAPT	O14757	CHEK1	S531	R526L	526	Missense	distal	-5	no	7.782	10.758	EPSD	CCLE	5.604	Up-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	P10636	MAPT	O14757	CHEK1	S554	R559H	559	Missense	distal	5	no	6.234	6.250	EPSD	CCLE	5.604	Up-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	P10636	MAPT	O14757	CHEK1	T562	R559H	559	Missense	distal	-3	no	9.518	3.709	EPSD	CCLE	5.604	Loss
CAMK_CAMKL_CHK1_CHEK1_ST	P10636	MAPT	O14757	CHEK1	S579	K574N	574	Missense	distal	-5	no	6.137	5.243	EPSD	CCLE	5.604	Loss
CAMK_CAMKL_CHK1_CHEK1_ST	P10636	MAPT	O14757	CHEK1	S637	D631E	631	Missense	distal	-6	no	7.829	7.879	EPSD	CCLE	5.604	Up-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	P10636	MAPT	O14757	CHEK1	S726	S721C	721	Missense	distal	-5	no	10.748	10.280	EPSD	CCLE	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	P10636	MAPT	O14757	CHEK1	S726	H724R	724	Missense	proximal	-2	no	10.748	10.683	EPSD	CCLE	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q14676	MDC1	O14757	CHEK1	S485	R478S	478	Missense	distal	-7	no	13.565	13.824	EPSD	CCLE	5.604	Up-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q14676	MDC1	O14757	CHEK1	T844	E841K	841	Missense	distal	-3	no	3.541	6.804	EPSD	CCLE	5.604	Gain
CAMK_CAMKL_CHK1_CHEK1_ST	Q14676	MDC1	O14757	CHEK1	S874	E879G	879	Missense	distal	5	no	7.950	7.673	EPSD	CCLE	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q14676	MDC1	O14757	CHEK1	T1623	E1618K	1618	Missense	distal	-5	no	4.093	6.655	EPSD	CCLE	5.604	Gain
CAMK_CAMKL_CHK1_CHEK1_ST	Q14676	MDC1	O14757	CHEK1	T1688	M1692I	1692	Missense	distal	4	no	7.838	7.780	EPSD	CCLE	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	P25205	MCM3	O14757	CHEK1	S160	V166M	166	Missense	distal	6	no	12.830	12.955	PhosphoSitePlus	CCLE	5.604	Up-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	P25205	MCM3	O14757	CHEK1	S374	R371Q	371	Missense	distal	-3	no	10.691	3.484	EPSD	CCLE	5.604	Loss
CAMK_CAMKL_CHK1_CHEK1_ST	P25205	MCM3	O14757	CHEK1	S668	R667P	667	Missense	proximal	-1	no	11.313	11.599	EPSD	CCLE	5.604	Up-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	O95707	POP4	O14757	CHEK1	S10	A8P	8	Missense	proximal	-2	no	6.269	6.439	PhosphoSitePlus	CCLE	5.604	Up-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	P35612	ADD2	O14757	CHEK1	S62	L67V	67	Missense	distal	5	no	6.159	6.318	EPSD	CCLE	5.604	Up-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	P35611	ADD1	O14757	CHEK1	S353	K348T	348	Missense	distal	-5	no	6.163	5.909	EPSD	CCLE	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	P35611	ADD1	O14757	CHEK1	S355	K348T	348	Missense	distal	-7	no	7.969	6.182	EPSD	CCLE	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	P35611	ADD1	O14757	CHEK1	S408	K403R	403	Missense	distal	-5	no	8.571	7.396	EPSD	CCLE	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	P35611	ADD1	O14757	CHEK1	S645	L644M	644	Missense	proximal	-1	no	5.682	5.632	EPSD	CCLE	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	P35611	ADD1	O14757	CHEK1	S669	A664V	664	Missense	distal	-5	no	6.914	9.353	EPSD	CCLE	5.604	Up-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	P35611	ADD1	O14757	CHEK1	S669	R666S	666	Missense	distal	-3	no	6.914	-2.782	EPSD	CCLE	5.604	Loss
CAMK_CAMKL_CHK1_CHEK1_ST	P35611	ADD1	O14757	CHEK1	S669	S669R	669	Missense	central	0	yes	6.914	0.000	EPSD	CCLE	5.604	Loss
CAMK_CAMKL_CHK1_CHEK1_ST	Q6UB98	ANKRD12	O14757	CHEK1	S1085	S1079T	1079	Missense	distal	-6	no	8.603	8.673	EPSD	CCLE	5.604	Up-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q6UB98	ANKRD12	O14757	CHEK1	S1166	S1164L	1164	Missense	proximal	-2	no	8.505	8.610	EPSD	CCLE	5.604	Up-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q6UB98	ANKRD12	O14757	CHEK1	S1650	N1656S	1656	Missense	distal	6	no	7.093	6.958	EPSD	CCLE	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	P12956	XRCC6	O14757	CHEK1	S477	R470L	470	Missense	distal	-7	no	12.198	11.574	PhosphoSitePlus	CCLE	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q13043	STK4	O14757	CHEK1	T120	K119R	119	Missense	proximal	-1	no	8.540	8.688	EPSD	CCLE	5.604	Up-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q13043	STK4	O14757	CHEK1	T122	K119R	119	Missense	distal	-3	no	6.461	10.286	EPSD	CCLE	5.604	Up-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	O75592	MYCBP2	O14757	CHEK1	S56	G53R	53	Missense	distal	-3	no	1.864	9.639	EPSD	CCLE	5.604	Gain
CAMK_CAMKL_CHK1_CHEK1_ST	O75592	MYCBP2	O14757	CHEK1	S89	V96I	96	Missense	distal	7	no	9.675	9.254	EPSD	CCLE	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	O75592	MYCBP2	O14757	CHEK1	S1176	Q1182H	1182	Missense	distal	6	no	6.584	6.878	EPSD	CCLE	5.604	Up-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	O75592	MYCBP2	O14757	CHEK1	S1189	Q1182H	1182	Missense	distal	-7	no	7.319	7.002	EPSD	CCLE	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	O75592	MYCBP2	O14757	CHEK1	S1472	M1479I	1479	Missense	distal	7	no	7.680	7.403	EPSD	CCLE	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	O75592	MYCBP2	O14757	CHEK1	S1586	D1590G	1590	Missense	distal	4	no	6.682	6.699	EPSD	CCLE	5.604	Up-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	O75592	MYCBP2	O14757	CHEK1	S2689	G2692R	2692	Missense	distal	3	no	5.830	5.915	EPSD	CCLE	5.604	Up-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	O75592	MYCBP2	O14757	CHEK1	S2768	P2775L	2775	Missense	distal	7	no	10.948	10.885	EPSD	CCLE	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	O75592	MYCBP2	O14757	CHEK1	S2774	R2780W	2780	Missense	distal	6	no	6.470	6.937	EPSD	CCLE	5.604	Up-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	O75592	MYCBP2	O14757	CHEK1	S2774	P2775L	2775	Missense	proximal	1	no	6.470	6.498	EPSD	CCLE	5.604	Up-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	O75592	MYCBP2	O14757	CHEK1	S2783	R2780W	2780	Missense	distal	-3	no	9.509	-24.095	EPSD	CCLE	5.604	Loss
CAMK_CAMKL_CHK1_CHEK1_ST	Q9BRD0	BUD13	O14757	CHEK1	T159	P162A	162	Missense	distal	3	no	8.933	8.698	EPSD	CCLE	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	O60343	TBC1D4	O14757	CHEK1	S102	P97L	97	Missense	distal	-5	no	1.809	6.516	EPSD	CCLE	5.604	Gain
CAMK_CAMKL_CHK1_CHEK1_ST	O60343	TBC1D4	O14757	CHEK1	S318	V322M	322	Missense	distal	4	no	9.143	9.142	EPSD	CCLE	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	O60343	TBC1D4	O14757	CHEK1	S341	P343S	343	Missense	proximal	2	no	7.708	7.784	EPSD	CCLE	5.604	Up-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	O60343	TBC1D4	O14757	CHEK1	S597	S597R	597	Missense	central	0	yes	9.239	0.000	EPSD	CCLE	5.604	Loss
CAMK_CAMKL_CHK1_CHEK1_ST	O60343	TBC1D4	O14757	CHEK1	S600	S597R	597	Missense	distal	-3	no	1.920	11.616	EPSD	CCLE	5.604	Gain
CAMK_CAMKL_CHK1_CHEK1_ST	O60343	TBC1D4	O14757	CHEK1	T642	R639W	639	Missense	distal	-3	no	8.825	-24.778	EPSD	CCLE	5.604	Loss
CAMK_CAMKL_CHK1_CHEK1_ST	O60343	TBC1D4	O14757	CHEK1	T749	S750L	750	Missense	proximal	1	no	7.985	7.976	EPSD	CCLE	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	O60343	TBC1D4	O14757	CHEK1	S750	S750L	750	Missense	central	0	yes	6.571	0.000	EPSD	CCLE	5.604	Loss
CAMK_CAMKL_CHK1_CHEK1_ST	O60343	TBC1D4	O14757	CHEK1	S751	S750L	750	Missense	proximal	-1	no	10.184	10.445	EPSD	CCLE	5.604	Up-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	O60343	TBC1D4	O14757	CHEK1	S771	S771F	771	Missense	central	0	yes	9.775	0.000	EPSD	CCLE	5.604	Loss
CAMK_CAMKL_CHK1_CHEK1_ST	O60343	TBC1D4	O14757	CHEK1	S951	P947L	947	Missense	distal	-4	no	6.741	6.557	EPSD	CCLE	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	P36507	MAP2K2	O14757	CHEK1	S306	R299K	299	Missense	distal	-7	no	8.439	9.619	EPSD	CCLE	5.604	Up-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q9GZR7	DDX24	O14757	CHEK1	T532	K527E	527	Missense	distal	-5	no	5.746	3.184	EPSD	CCLE	5.604	Loss
CAMK_CAMKL_CHK1_CHEK1_ST	Q14247	CTTN	O14757	CHEK1	S113	S106L	106	Missense	distal	-7	no	11.869	10.985	EPSD	CCLE	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q14247	CTTN	O14757	CHEK1	S155	F158V	158	Missense	distal	3	no	6.590	6.740	EPSD	CCLE	5.604	Up-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q14247	CTTN	O14757	CHEK1	S192	G196S	196	Missense	distal	4	no	9.783	9.716	EPSD	CCLE	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q14247	CTTN	O14757	CHEK1	S282	G286E	286	Missense	distal	4	no	8.959	8.851	EPSD	CCLE	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q9BTD8	RBM42	O14757	CHEK1	S406	S402G	402	Missense	distal	-4	no	11.286	11.620	PhosphoSitePlus	CCLE	5.604	Up-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	P39748	FEN1	O14757	CHEK1	T195	M191I	191	Missense	distal	-4	no	12.080	11.956	PhosphoSitePlus	CCLE	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q13263	TRIM28	O14757	CHEK1	T34	S37L	37	Missense	distal	3	no	5.619	5.185	EPSD	CCLE	5.604	Loss
CAMK_CAMKL_CHK1_CHEK1_ST	Q13263	TRIM28	O14757	CHEK1	T34	A38V	38	Missense	distal	4	no	5.619	5.536	EPSD	CCLE	5.604	Loss
CAMK_CAMKL_CHK1_CHEK1_ST	Q13263	TRIM28	O14757	CHEK1	T34	S41W	41	Missense	distal	7	no	5.619	5.210	EPSD	CCLE	5.604	Loss
CAMK_CAMKL_CHK1_CHEK1_ST	P49792	RANBP2	O14757	CHEK1	S26	Q24E	24	Missense	proximal	-2	no	10.697	10.613	EPSD	CCLE	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	P49792	RANBP2	O14757	CHEK1	T1992	A1987T	1987	Missense	distal	-5	no	5.696	9.557	EPSD	CCLE	5.604	Up-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	P49792	RANBP2	O14757	CHEK1	T2458	S2457G	2457	Missense	proximal	-1	no	6.832	7.010	EPSD	CCLE	5.604	Up-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q9BQG0	MYBBP1A	O14757	CHEK1	T637	P632A	632	Missense	distal	-5	no	6.856	5.646	EPSD	CCLE	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q9BQG0	MYBBP1A	O14757	CHEK1	S775	S775N	775	Missense	central	0	yes	8.939	0.000	EPSD	CCLE	5.604	Loss
CAMK_CAMKL_CHK1_CHEK1_ST	Q9BQG0	MYBBP1A	O14757	CHEK1	S864	S859G	859	Missense	distal	-5	no	9.189	9.235	EPSD	CCLE	5.604	Up-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q9BQG0	MYBBP1A	O14757	CHEK1	S864	R858H	858	Missense	distal	-6	no	9.189	9.299	EPSD	CCLE	5.604	Up-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q08AD1	CAMSAP2	O14757	CHEK1	S677	K682T	682	Missense	distal	5	no	5.615	5.373	EPSD	CCLE	5.604	Loss
CAMK_CAMKL_CHK1_CHEK1_ST	Q08AD1	CAMSAP2	O14757	CHEK1	S687	K682T	682	Missense	distal	-5	no	7.151	6.896	EPSD	CCLE	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q08AD1	CAMSAP2	O14757	CHEK1	S699	R706K	706	Missense	distal	7	no	5.540	5.615	EPSD	CCLE	5.604	Gain
CAMK_CAMKL_CHK1_CHEK1_ST	Q08AD1	CAMSAP2	O14757	CHEK1	S844	E850V	850	Missense	distal	6	no	7.017	7.563	EPSD	CCLE	5.604	Up-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q08AD1	CAMSAP2	O14757	CHEK1	S980	S974C	974	Missense	distal	-6	no	6.922	6.958	EPSD	CCLE	5.604	Up-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	P30305	CDC25B	O14757	CHEK1	S375	R372H	372	Missense	distal	-3	no	9.149	3.340	EPSD	CCLE	5.604	Loss
CAMK_CAMKL_CHK1_CHEK1_ST	Q5JSZ5	PRRC2B	O14757	CHEK1	S104	L110Q	110	Missense	distal	6	no	5.996	5.668	EPSD	CCLE	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q5JSZ5	PRRC2B	O14757	CHEK1	S166	G160S	160	Missense	distal	-6	no	9.677	9.639	PhosphoSitePlus	CCLE	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q5JSZ5	PRRC2B	O14757	CHEK1	T736	R733I	733	Missense	distal	-3	no	6.742	-2.016	EPSD	CCLE	5.604	Loss
CAMK_CAMKL_CHK1_CHEK1_ST	Q5JSZ5	PRRC2B	O14757	CHEK1	S778	S781C	781	Missense	distal	3	no	7.062	6.112	EPSD	CCLE	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q5JSZ5	PRRC2B	O14757	CHEK1	S2085	Q2087P	2087	Missense	proximal	2	no	11.961	11.451	EPSD	CCLE	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	P02545	LMNA	O14757	CHEK1	T224	T224A	224	Missense	central	0	yes	10.611	0.000	EPSD	CCLE	5.604	Loss
CAMK_CAMKL_CHK1_CHEK1_ST	P02545	LMNA	O14757	CHEK1	S657	P658S	658	Missense	proximal	1	no	10.155	10.192	EPSD	CCLE	5.604	Up-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	O95625	ZBTB11	O14757	CHEK1	S130	S133L	133	Missense	distal	3	no	9.242	8.808	EPSD	CCLE	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	O95625	ZBTB11	O14757	CHEK1	S442	S448R	448	Missense	distal	6	no	5.826	5.914	EPSD	CCLE	5.604	Up-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	O95625	ZBTB11	O14757	CHEK1	S511	S505T	505	Missense	distal	-6	no	9.371	9.440	EPSD;PhosphoSitePlus	CCLE	5.604	Up-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	O95625	ZBTB11	O14757	CHEK1	S511	R504T	504	Missense	distal	-7	no	9.371	8.763	EPSD;PhosphoSitePlus	CCLE	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q9UPP1	PHF8	O14757	CHEK1	S1021	N1027S	1027	Missense	distal	6	no	11.227	11.092	EPSD	CCLE	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q9H0H5	RACGAP1	O14757	CHEK1	T63	A61T	61	Missense	proximal	-2	no	8.710	8.849	EPSD	CCLE	5.604	Up-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q9H0H5	RACGAP1	O14757	CHEK1	T145	I152L	152	Missense	distal	7	no	9.217	9.501	EPSD	CCLE	5.604	Up-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q9H0H5	RACGAP1	O14757	CHEK1	S257	L261P	261	Missense	distal	4	no	5.844	5.948	EPSD	CCLE	5.604	Up-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q9H0H5	RACGAP1	O14757	CHEK1	S590	P589T	589	Missense	proximal	-1	no	8.547	8.304	EPSD	CCLE	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q9H0H5	RACGAP1	O14757	CHEK1	S600	P607S	607	Missense	distal	7	no	9.329	9.274	EPSD	CCLE	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q9H0H5	RACGAP1	O14757	CHEK1	S600	R599H	599	Missense	proximal	-1	no	9.329	9.455	EPSD	CCLE	5.604	Up-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q9H0H5	RACGAP1	O14757	CHEK1	S611	S615P	615	Missense	distal	4	no	8.941	9.081	EPSD	CCLE	5.604	Up-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q9H0H5	RACGAP1	O14757	CHEK1	S611	P607S	607	Missense	distal	-4	no	8.941	8.704	EPSD	CCLE	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q92974	ARHGEF2	O14757	CHEK1	S142	A147T	147	Missense	distal	5	no	6.650	6.409	EPSD	CCLE	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q92974	ARHGEF2	O14757	CHEK1	S151	A147T	147	Missense	distal	-4	no	7.223	6.792	EPSD	CCLE	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q92974	ARHGEF2	O14757	CHEK1	S172	R168H	168	Missense	distal	-4	no	10.777	10.580	PhosphoSitePlus	CCLE	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q92974	ARHGEF2	O14757	CHEK1	S186	E193Q	193	Missense	distal	7	no	7.012	6.927	EPSD	CCLE	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q92974	ARHGEF2	O14757	CHEK1	T455	A453T	453	Missense	proximal	-2	no	7.432	7.571	EPSD	CCLE	5.604	Up-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q92974	ARHGEF2	O14757	CHEK1	S645	L646P	646	Missense	proximal	1	no	10.882	10.854	EPSD	CCLE	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q92974	ARHGEF2	O14757	CHEK1	S645	R642S	642	Missense	distal	-3	no	10.882	1.186	EPSD	CCLE	5.604	Loss
CAMK_CAMKL_CHK1_CHEK1_ST	Q92974	ARHGEF2	O14757	CHEK1	S782	R779Q	779	Missense	distal	-3	no	11.920	4.713	EPSD	CCLE	5.604	Loss
CAMK_CAMKL_CHK1_CHEK1_ST	P27816	MAP4	O14757	CHEK1	S801	A796S	796	Missense	distal	-5	no	6.145	8.873	EPSD	CCLE	5.604	Up-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	O43395	PRPF3	O14757	CHEK1	S174	T167A	167	Missense	distal	-7	no	8.206	9.523	EPSD	CCLE	5.604	Up-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q00341	HDLBP	O14757	CHEK1	T149	A156P	156	Missense	distal	7	no	6.467	6.474	EPSD	CCLE	5.604	Up-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q00341	HDLBP	O14757	CHEK1	S904	T900I	900	Missense	distal	-4	no	11.035	11.107	EPSD	CCLE	5.604	Up-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q86WR7	PROSER2	O14757	CHEK1	S328	P323L	323	Missense	distal	-5	no	1.309	6.016	EPSD	CCLE	5.604	Gain
CAMK_CAMKL_CHK1_CHEK1_ST	Q86WR7	PROSER2	O14757	CHEK1	S400	R397H	397	Missense	distal	-3	no	8.119	2.310	EPSD	CCLE	5.604	Loss
CAMK_CAMKL_CHK1_CHEK1_ST	Q86WR7	PROSER2	O14757	CHEK1	S400	R397L	397	Missense	distal	-3	no	8.119	-10.427	EPSD	CCLE	5.604	Loss
CAMK_CAMKL_CHK1_CHEK1_ST	Q86WR7	PROSER2	O14757	CHEK1	S400	P402L	402	Missense	proximal	2	no	8.119	7.802	EPSD	CCLE	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q14004	CDK13	O14757	CHEK1	S285	P290L	290	Missense	distal	5	no	11.317	11.155	EPSD	CCLE	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q14004	CDK13	O14757	CHEK1	S342	R338P	338	Missense	distal	-4	no	5.769	5.697	EPSD	CCLE	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q14004	CDK13	O14757	CHEK1	S342	G346C	346	Missense	distal	4	no	5.769	5.856	EPSD	CCLE	5.604	Up-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q14004	CDK13	O14757	CHEK1	S342	G347R	347	Missense	distal	5	no	5.769	5.857	EPSD	CCLE	5.604	Up-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q14004	CDK13	O14757	CHEK1	S630	I629V	629	Missense	proximal	-1	no	5.529	5.667	EPSD	CCLE	5.604	Gain
CAMK_CAMKL_CHK1_CHEK1_ST	Q14004	CDK13	O14757	CHEK1	S863	P869A	869	Missense	distal	6	no	12.300	12.068	EPSD	CCLE	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q14004	CDK13	O14757	CHEK1	T871	P869A	869	Missense	proximal	-2	no	8.053	7.883	EPSD	CCLE	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q6T4R5	NHS	O14757	CHEK1	S140	R137W	137	Missense	distal	-3	no	10.545	-23.058	EPSD	CCLE	5.604	Loss
CAMK_CAMKL_CHK1_CHEK1_ST	Q5JTH9	RRP12	O14757	CHEK1	S9	S4W	4	Missense	distal	-5	no	7.159	6.511	EPSD	CCLE	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q5JTH9	RRP12	O14757	CHEK1	S23	R17H	17	Missense	distal	-6	no	6.161	6.270	EPSD	CCLE	5.604	Up-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q5JTH9	RRP12	O14757	CHEK1	S652	R645Q	645	Missense	distal	-7	no	7.770	8.028	EPSD	CCLE	5.604	Up-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q5JTH9	RRP12	O14757	CHEK1	S737	D742N	742	Missense	distal	5	no	8.407	8.318	EPSD	CCLE	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q5JTH9	RRP12	O14757	CHEK1	S746	D742N	742	Missense	distal	-4	no	6.596	6.520	EPSD	CCLE	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q5JTH9	RRP12	O14757	CHEK1	S829	P831S	831	Missense	proximal	2	no	6.515	6.591	EPSD	CCLE	5.604	Up-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q5JTH9	RRP12	O14757	CHEK1	S829	R826W	826	Missense	distal	-3	no	6.515	-27.089	EPSD	CCLE	5.604	Loss
CAMK_CAMKL_CHK1_CHEK1_ST	Q5JTH9	RRP12	O14757	CHEK1	S1105	A1101V	1101	Missense	distal	-4	no	10.895	10.816	EPSD	CCLE	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q9HAW4	CLSPN	O14757	CHEK1	S1156	M1149T	1149	Missense	distal	-7	no	8.978	8.511	EPSD	CCLE	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q9HAW4	CLSPN	O14757	CHEK1	S1223	K1220N	1220	Missense	distal	-3	no	9.247	2.705	EPSD	CCLE	5.604	Loss
CAMK_CAMKL_CHK1_CHEK1_ST	Q14738	PPP2R5D	O14757	CHEK1	S573	K572R	572	Missense	proximal	-1	no	13.785	13.933	EPSD	CCLE	5.604	Up-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	P55039	DRG2	O14757	CHEK1	S49	P44T	44	Missense	distal	-5	no	3.238	5.889	EPSD	CCLE	5.604	Gain
CAMK_CAMKL_CHK1_CHEK1_ST	P55039	DRG2	O14757	CHEK1	S72	L79V	79	Missense	distal	7	no	5.814	5.950	PhosphoSitePlus	CCLE	5.604	Up-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	P15822	HIVEP1	O14757	CHEK1	S577	K584R	584	Missense	distal	7	no	9.026	8.951	EPSD	CCLE	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	P15822	HIVEP1	O14757	CHEK1	S779	P783L	783	Missense	distal	4	no	10.293	10.190	EPSD	CCLE	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	P15822	HIVEP1	O14757	CHEK1	S1387	D1382H	1382	Missense	distal	-5	no	6.320	4.842	EPSD	CCLE	5.604	Loss
CAMK_CAMKL_CHK1_CHEK1_ST	P15822	HIVEP1	O14757	CHEK1	S1952	K1958N	1958	Missense	distal	6	no	11.395	11.529	EPSD	CCLE	5.604	Up-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	P15822	HIVEP1	O14757	CHEK1	S2101	K2104R	2104	Missense	distal	3	no	5.982	5.336	EPSD	CCLE	5.604	Loss
CAMK_CAMKL_CHK1_CHEK1_ST	P15822	HIVEP1	O14757	CHEK1	S2599	E2598K	2598	Missense	proximal	-1	no	8.799	8.741	EPSD	CCLE	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q9BY77	POLDIP3	O14757	CHEK1	S375	E376K	376	Missense	proximal	1	no	6.093	6.019	EPSD	CCLE	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q9BY77	POLDIP3	O14757	CHEK1	S383	E376K	376	Missense	distal	-7	no	9.236	9.933	EPSD	CCLE	5.604	Up-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	P26373	RPL13	O14757	CHEK1	S106	N113S	113	Missense	distal	7	no	8.211	7.982	EPSD	CCLE	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	P26373	RPL13	O14757	CHEK1	S132	S139G	139	Missense	distal	7	no	7.319	7.417	EPSD	CCLE	5.604	Up-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	P26373	RPL13	O14757	CHEK1	S139	S139G	139	Missense	central	0	yes	6.106	0.000	EPSD	CCLE	5.604	Loss
CAMK_CAMKL_CHK1_CHEK1_ST	P26373	RPL13	O14757	CHEK1	S140	S139G	139	Missense	proximal	-1	no	6.494	6.673	EPSD	CCLE	5.604	Up-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	P18858	LIG1	O14757	CHEK1	S201	P196L	196	Missense	distal	-5	no	3.101	7.807	EPSD	CCLE	5.604	Gain
CAMK_CAMKL_CHK1_CHEK1_ST	P18858	LIG1	O14757	CHEK1	S447	R451C	451	Missense	distal	4	no	8.545	8.649	EPSD	CCLE	5.604	Up-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q8N4C8	MINK1	O14757	CHEK1	T59	A52V	52	Missense	distal	-7	no	5.783	5.127	EPSD	CCLE	5.604	Loss
CAMK_CAMKL_CHK1_CHEK1_ST	Q8N4C8	MINK1	O14757	CHEK1	T59	D61E	61	Missense	proximal	2	no	5.783	5.866	EPSD	CCLE	5.604	Up-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q8N4C8	MINK1	O14757	CHEK1	T187	G183S	183	Missense	distal	-4	no	8.698	8.364	EPSD	CCLE	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q8N4C8	MINK1	O14757	CHEK1	T187	R185W	185	Missense	proximal	-2	no	8.698	8.819	EPSD	CCLE	5.604	Up-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	P30307	CDC25C	O14757	CHEK1	T236	D239H	239	Missense	distal	3	no	5.722	4.193	EPSD	CCLE	5.604	Loss
CAMK_CAMKL_CHK1_CHEK1_ST	P30307	CDC25C	O14757	CHEK1	S449	G456R	456	Missense	distal	7	no	9.931	9.925	EPSD	CCLE	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	P30307	CDC25C	O14757	CHEK1	S451	G456R	456	Missense	distal	5	no	6.936	7.024	EPSD	CCLE	5.604	Up-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	P06400	RB1	O14757	CHEK1	S612	P609H	609	Missense	distal	-3	no	6.544	7.871	PhosphoSitePlus	CCLE	5.604	Up-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	P19838	NFKB1	O14757	CHEK1	S899	S893N	893	Missense	distal	-6	no	7.058	7.099	EPSD	CCLE	5.604	Up-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q96RL1	UIMC1	O14757	CHEK1	S343	E340K	340	Missense	distal	-3	no	2.765	6.028	EPSD	CCLE	5.604	Gain
CAMK_CAMKL_CHK1_CHEK1_ST	Q96ST3	SIN3A	O14757	CHEK1	T432	C425W	425	Missense	distal	-7	no	9.233	8.415	EPSD	CCLE	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q96ST3	SIN3A	O14757	CHEK1	S451	S450F	450	Missense	proximal	-1	no	7.803	8.077	EPSD	CCLE	5.604	Up-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q13470	TNK1	O14757	CHEK1	T258	S255P	255	Missense	distal	-3	no	5.942	8.501	EPSD	CCLE	5.604	Up-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q32P44	EML3	O14757	CHEK1	S176	L170V	170	Missense	distal	-6	no	8.278	8.265	PhosphoSitePlus	CCLE	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q32P44	EML3	O14757	CHEK1	S887	P886F	886	Missense	proximal	-1	no	8.202	8.029	EPSD	CCLE	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q9Y4F5	CEP170B	O14757	CHEK1	S371	A367V	367	Missense	distal	-4	no	8.771	8.692	EPSD	CCLE	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q9Y4F5	CEP170B	O14757	CHEK1	S421	G428R	428	Missense	distal	7	no	8.973	8.967	EPSD	CCLE	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q9Y4F5	CEP170B	O14757	CHEK1	S605	L600I	600	Missense	distal	-5	no	12.206	10.174	EPSD	CCLE	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q9Y4F5	CEP170B	O14757	CHEK1	S605	S604F	604	Missense	proximal	-1	no	12.206	12.480	EPSD	CCLE	5.604	Up-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q9Y4F5	CEP170B	O14757	CHEK1	S636	E633D	633	Missense	distal	-3	no	6.435	4.187	EPSD	CCLE	5.604	Loss
CAMK_CAMKL_CHK1_CHEK1_ST	Q9Y4F5	CEP170B	O14757	CHEK1	S636	P643S	643	Missense	distal	7	no	6.435	6.380	EPSD	CCLE	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q9Y4F5	CEP170B	O14757	CHEK1	S711	L704V	704	Missense	distal	-7	no	7.834	8.512	EPSD	CCLE	5.604	Up-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q9Y4F5	CEP170B	O14757	CHEK1	S772	S768T	768	Missense	distal	-4	no	8.222	8.171	EPSD	CCLE	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q9Y4F5	CEP170B	O14757	CHEK1	S930	R927Q	927	Missense	distal	-3	no	7.980	0.773	EPSD	CCLE	5.604	Loss
CAMK_CAMKL_CHK1_CHEK1_ST	Q9Y4F5	CEP170B	O14757	CHEK1	S1007	R1004S	1004	Missense	distal	-3	no	8.938	-0.758	EPSD	CCLE	5.604	Loss
CAMK_CAMKL_CHK1_CHEK1_ST	Q9Y4F5	CEP170B	O14757	CHEK1	S1007	R1010K	1010	Missense	distal	3	no	8.938	9.585	EPSD	CCLE	5.604	Up-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q9Y4F5	CEP170B	O14757	CHEK1	S1114	R1111H	1111	Missense	distal	-3	no	12.353	6.544	EPSD	CCLE	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q9Y4F5	CEP170B	O14757	CHEK1	S1179	G1178S	1178	Missense	proximal	-1	no	6.912	6.733	EPSD	CCLE	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q9Y4F5	CEP170B	O14757	CHEK1	T1210	R1215W	1215	Missense	distal	5	no	7.302	7.133	EPSD	CCLE	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q8WWI1	LMO7	O14757	CHEK1	S56	R51G	51	Missense	distal	-5	no	10.722	10.557	EPSD	CCLE	5.604	Down-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q8WWI1	LMO7	O14757	CHEK1	S246	D245G	245	Missense	proximal	-1	no	8.531	8.580	EPSD	CCLE	5.604	Up-regulation
CAMK_CAMKL_CHK1_CHEK1_ST	Q8WWI1	LMO7	O14757	CHEK1	S751	D755Y	755	Missense	distal	4	no	7.402	7.526	EPSD	CCLE	5.604	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q9Y6W5	WASF2	P27361	MAPK3	S296	P302A	302	Missense	distal	6	no	16.695	16.299	EPSD	CCLE	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q9Y6W5	WASF2	P27361	MAPK3	S308	P302A	302	Missense	distal	-6	no	17.128	16.896	EPSD	CCLE	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q9Y6W5	WASF2	P27361	MAPK3	S474	R475H	475	Missense	proximal	1	no	7.686	9.431	EPSD	CCLE	9.358	Gain
CMGC_MAPK_ERK1_MAPK3_ST	P11388	TOP2A	P27361	MAPK3	S387	P385A	385	Missense	proximal	-2	no	12.402	10.051	EPSD	CCLE	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P11388	TOP2A	P27361	MAPK3	S1162	T1157I	1157	Missense	distal	-5	no	17.955	17.877	EPSD	CCLE	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P11388	TOP2A	P27361	MAPK3	S1393	P1394R	1394	Missense	proximal	1	no	15.613	6.112	EPSD;PhosphoSitePlus	CCLE	9.358	Loss
CMGC_MAPK_ERK1_MAPK3_ST	Q07820	MCL1	P27361	MAPK3	S67	R74L	74	Missense	distal	7	no	9.460	9.561	EPSD	CCLE	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q07820	MCL1	P27361	MAPK3	S67	R74Q	74	Missense	distal	7	no	9.460	9.490	EPSD	CCLE	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q07820	MCL1	P27361	MAPK3	S67	S73P	73	Missense	distal	6	no	9.460	9.331	EPSD	CCLE	9.358	Loss
CMGC_MAPK_ERK1_MAPK3_ST	Q07820	MCL1	P27361	MAPK3	T70	R74L	74	Missense	distal	4	no	16.270	16.214	EPSD	CCLE	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q07820	MCL1	P27361	MAPK3	T70	R74Q	74	Missense	distal	4	no	16.270	16.226	EPSD	CCLE	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q07820	MCL1	P27361	MAPK3	T70	S73P	73	Missense	distal	3	no	16.270	16.275	EPSD	CCLE	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q07820	MCL1	P27361	MAPK3	S73	R74Q	74	Missense	proximal	1	no	8.544	10.101	EPSD	CCLE	9.358	Gain
CMGC_MAPK_ERK1_MAPK3_ST	Q07820	MCL1	P27361	MAPK3	T92	D88N	88	Missense	distal	-4	no	13.770	13.744	PhosphoSitePlus;EPSD	CCLE	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q07820	MCL1	P27361	MAPK3	T163	T156R	156	Missense	distal	-7	no	16.774	16.780	EPSD;PhosphoSitePlus	CCLE	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P15056	BRAF	P27361	MAPK3	S750	I755F	755	Missense	distal	5	no	17.108	17.077	EPSD	CCLE	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P15056	BRAF	P27361	MAPK3	T753	I755F	755	Missense	proximal	2	no	19.962	19.947	EPSD;PhosphoSitePlus	CCLE	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P04626	ERBB2	P27361	MAPK3	S1174	V1181I	1181	Missense	distal	7	no	17.467	17.548	EPSD	CCLE	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P04626	ERBB2	P27361	MAPK3	S1214	P1209L	1209	Missense	distal	-5	no	16.479	16.424	EPSD	CCLE	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P10636	MAPT	P27361	MAPK3	S68	A66V	66	Missense	proximal	-2	no	9.012	9.708	EPSD	CCLE	9.358	Gain
CMGC_MAPK_ERK1_MAPK3_ST	P10636	MAPT	P27361	MAPK3	T69	A66V	66	Missense	distal	-3	no	15.297	15.316	EPSD	CCLE	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P10636	MAPT	P27361	MAPK3	T111	G107V	107	Missense	distal	-4	no	15.249	15.136	EPSD	CCLE	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P10636	MAPT	P27361	MAPK3	S228	D221Y	221	Missense	distal	-7	no	17.196	17.271	EPSD	CCLE	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P10636	MAPT	P27361	MAPK3	S228	P234S	234	Missense	distal	6	no	17.196	17.325	EPSD	CCLE	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P10636	MAPT	P27361	MAPK3	S232	P234S	234	Missense	proximal	2	no	16.576	16.578	EPSD	CCLE	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P10636	MAPT	P27361	MAPK3	S238	P234S	234	Missense	distal	-4	no	16.113	16.140	EPSD	CCLE	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P10636	MAPT	P27361	MAPK3	S238	D242H	242	Missense	distal	4	no	16.113	16.092	EPSD	CCLE	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P10636	MAPT	P27361	MAPK3	S411	K405R	405	Missense	distal	-6	no	14.840	14.838	EPSD	CCLE	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P10636	MAPT	P27361	MAPK3	S438	V442I	442	Missense	distal	4	no	20.015	19.897	EPSD	CCLE	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P10636	MAPT	P27361	MAPK3	S516	R511H	511	Missense	distal	-5	no	17.816	17.825	EPSD	CCLE	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P10636	MAPT	P27361	MAPK3	S516	G518S	518	Missense	proximal	2	no	17.816	17.833	EPSD	CCLE	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P10636	MAPT	P27361	MAPK3	S519	G518S	518	Missense	proximal	-1	no	18.268	18.334	EPSD	CCLE	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P10636	MAPT	P27361	MAPK3	S519	R526L	526	Missense	distal	7	no	18.268	18.368	EPSD	CCLE	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P10636	MAPT	P27361	MAPK3	T522	G518S	518	Missense	distal	-4	no	17.797	17.835	EPSD	CCLE	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P10636	MAPT	P27361	MAPK3	T522	R526L	526	Missense	distal	4	no	17.797	17.740	EPSD	CCLE	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P10636	MAPT	P27361	MAPK3	S525	R526L	526	Missense	proximal	1	no	9.028	9.490	EPSD	CCLE	9.358	Gain
CMGC_MAPK_ERK1_MAPK3_ST	P10636	MAPT	P27361	MAPK3	T529	R526L	526	Missense	distal	-3	no	14.948	14.910	EPSD	CCLE	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P10636	MAPT	P27361	MAPK3	S552	R559H	559	Missense	distal	7	no	17.740	17.708	EPSD	CCLE	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P10636	MAPT	P27361	MAPK3	S713	G706V	706	Missense	distal	-7	no	17.918	18.029	EPSD	CCLE	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P10636	MAPT	P27361	MAPK3	S713	S717C	717	Missense	distal	4	no	17.918	17.414	EPSD	CCLE	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P10636	MAPT	P27361	MAPK3	S721	S717C	717	Missense	distal	-4	no	16.315	16.077	EPSD	CCLE	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P10636	MAPT	P27361	MAPK3	S721	S721C	721	Missense	central	0	yes	16.315	0.000	EPSD	CCLE	9.358	Loss
CMGC_MAPK_ERK1_MAPK3_ST	P10636	MAPT	P27361	MAPK3	S721	H724R	724	Missense	distal	3	no	16.315	16.307	EPSD	CCLE	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P10636	MAPT	P27361	MAPK3	S739	Q741K	741	Missense	proximal	2	no	19.967	19.972	EPSD	CCLE	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P10636	MAPT	P27361	MAPK3	T744	Q741K	741	Missense	distal	-3	no	9.660	9.654	EPSD	CCLE	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q13541	EIF4EBP1	P27361	MAPK3	T18	R19C	19	Missense	proximal	1	no	10.996	5.189	EPSD	CCLE	9.358	Loss
CMGC_MAPK_ERK1_MAPK3_ST	Q13541	EIF4EBP1	P27361	MAPK3	S65	P66H	66	Missense	proximal	1	no	14.573	6.817	PhosphoSitePlus	CCLE	9.358	Loss
CMGC_MAPK_ERK1_MAPK3_ST	Q13541	EIF4EBP1	P27361	MAPK3	T70	P66H	66	Missense	distal	-4	no	16.526	16.491	EPSD	CCLE	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q13541	EIF4EBP1	P27361	MAPK3	S94	R99C	99	Missense	distal	5	no	10.288	9.908	EPSD	CCLE	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q13541	EIF4EBP1	P27361	MAPK3	S96	R99C	99	Missense	distal	3	no	11.635	11.572	EPSD	CCLE	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q13541	EIF4EBP1	P27361	MAPK3	S101	R99C	99	Missense	proximal	-2	no	17.868	15.752	EPSD	CCLE	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P49715	CEBPA	P27361	MAPK3	T230	P237T	237	Missense	distal	7	no	16.495	16.536	EPSD	CCLE	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P49715	CEBPA	P27361	MAPK3	S234	P237T	237	Missense	distal	3	no	15.675	15.657	EPSD	CCLE	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P49715	CEBPA	P27361	MAPK3	S332	R325P	325	Missense	distal	-7	no	10.348	10.303	EPSD	CCLE	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P41235	HNF4A	P27361	MAPK3	S378	E372G	372	Missense	distal	-6	no	16.130	16.085	EPSD	CCLE	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P41235	HNF4A	P27361	MAPK3	S436	G440S	440	Missense	distal	4	no	15.690	15.851	EPSD	CCLE	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P41235	HNF4A	P27361	MAPK3	T455	G451K	451	Missense	distal	-4	no	9.549	9.504	EPSD	CCLE	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q9NYV6	RRN3	P27361	MAPK3	S44	P45H	45	Missense	proximal	1	no	15.208	7.452	EPSD	CCLE	9.358	Loss
CMGC_MAPK_ERK1_MAPK3_ST	Q9NYV6	RRN3	P27361	MAPK3	T200	P206S	206	Missense	distal	6	no	16.458	16.588	EPSD	CCLE	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q9NYV6	RRN3	P27361	MAPK3	T200	P201L	201	Missense	proximal	1	no	16.458	7.420	EPSD	CCLE	9.358	Loss
CMGC_MAPK_ERK1_MAPK3_ST	Q9NYV6	RRN3	P27361	MAPK3	T200	A194T	194	Missense	distal	-6	no	16.458	16.606	EPSD	CCLE	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P07101	TH	P27361	MAPK3	S62	R68H	68	Missense	distal	6	no	17.063	17.082	EPSD;PhosphoSitePlus	CCLE	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P07101	TH	P27361	MAPK3	S62	R68C	68	Missense	distal	6	no	17.063	16.437	EPSD;PhosphoSitePlus	CCLE	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P07101	TH	P27361	MAPK3	S62	S55F	55	Missense	distal	-7	no	17.063	17.282	EPSD;PhosphoSitePlus	CCLE	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P49790	NUP153	P27361	MAPK3	T369	I375V	375	Missense	distal	6	no	15.353	15.485	EPSD;PhosphoSitePlus	CCLE	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P49790	NUP153	P27361	MAPK3	S374	I375V	375	Missense	proximal	1	no	9.289	9.374	EPSD	CCLE	9.358	Gain
CMGC_MAPK_ERK1_MAPK3_ST	P49790	NUP153	P27361	MAPK3	T413	N411K	411	Missense	proximal	-2	no	14.096	13.776	EPSD;PhosphoSitePlus	CCLE	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P49790	NUP153	P27361	MAPK3	S619	S624Y	624	Missense	distal	5	no	14.573	14.357	EPSD	CCLE	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P49790	NUP153	P27361	MAPK3	S655	L656F	656	Missense	proximal	1	no	7.614	10.438	EPSD	CCLE	9.358	Gain
CMGC_MAPK_ERK1_MAPK3_ST	P49790	NUP153	P27361	MAPK3	S687	K685T	685	Missense	proximal	-2	no	13.863	15.218	EPSD	CCLE	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P49790	NUP153	P27361	MAPK3	T699	S703R	703	Missense	distal	4	no	15.269	15.122	EPSD	CCLE	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P49790	NUP153	P27361	MAPK3	S1152	M1155R	1155	Missense	distal	3	no	10.188	10.228	EPSD	CCLE	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P04049	RAF1	P27361	MAPK3	S359	S352L	352	Missense	distal	-7	no	9.764	9.909	EPSD	CCLE	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q16690	DUSP5	P27361	MAPK3	T321	N323S	323	Missense	proximal	2	no	16.427	16.445	EPSD;PhosphoSitePlus	CCLE	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P15336	ATF2	P27361	MAPK3	T69	R74K	74	Missense	distal	5	no	14.813	14.805	PhosphoSitePlus;EPSD	CCLE	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P15336	ATF2	P27361	MAPK3	T71	R74K	74	Missense	distal	3	no	14.842	14.840	EPSD;PhosphoSitePlus	CCLE	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P15336	ATF2	P27361	MAPK3	S314	A319D	319	Missense	distal	5	no	9.200	9.413	EPSD	CCLE	9.358	Gain
CMGC_MAPK_ERK1_MAPK3_ST	P15336	ATF2	P27361	MAPK3	T325	A330G	330	Missense	distal	5	no	14.306	14.496	EPSD	CCLE	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P15336	ATF2	P27361	MAPK3	T325	A319D	319	Missense	distal	-6	no	14.306	14.562	EPSD	CCLE	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P15336	ATF2	P27361	MAPK3	S328	A330G	330	Missense	proximal	2	no	17.676	17.698	EPSD	CCLE	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P15336	ATF2	P27361	MAPK3	T333	A330G	330	Missense	distal	-3	no	15.687	15.746	EPSD	CCLE	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P49023	PXN	P27361	MAPK3	S178	S178N	178	Missense	central	0	yes	15.251	0.000	EPSD	CCLE	9.358	Loss
CMGC_MAPK_ERK1_MAPK3_ST	P49023	PXN	P27361	MAPK3	S230	V237M	237	Missense	distal	7	no	14.654	14.786	EPSD	CCLE	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P49023	PXN	P27361	MAPK3	S244	E241K	241	Missense	distal	-3	no	12.682	12.650	EPSD	CCLE	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P49023	PXN	P27361	MAPK3	S244	V237M	237	Missense	distal	-7	no	12.682	12.738	EPSD	CCLE	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P14618	PKM	P27361	MAPK3	S420	V417M	417	Missense	distal	-3	no	11.313	11.258	EPSD	CCLE	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P56270	MAZ	P27361	MAPK3	T72	P76S	76	Missense	distal	4	no	15.569	15.618	PhosphoSitePlus	CCLE	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P56270	MAZ	P27361	MAPK3	T72	P76Q	76	Missense	distal	4	no	15.569	15.427	PhosphoSitePlus	CCLE	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q9BUB5	MKNK1	P27361	MAPK3	S437	R443L	443	Missense	distal	6	no	17.038	16.923	EPSD	CCLE	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q9UJY1	HSPB8	P27361	MAPK3	T87	E84D	84	Missense	distal	-3	no	14.689	14.685	EPSD;PhosphoSitePlus	CCLE	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q9UJY1	HSPB8	P27361	MAPK3	T87	P92H	92	Missense	distal	5	no	14.689	14.624	EPSD;PhosphoSitePlus	CCLE	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q05682	CALD1	P27361	MAPK3	S155	R156H	156	Missense	proximal	1	no	8.185	9.929	EPSD	CCLE	9.358	Gain
CMGC_MAPK_ERK1_MAPK3_ST	Q05682	CALD1	P27361	MAPK3	S724	F722L	722	Missense	proximal	-2	no	15.284	16.276	EPSD	CCLE	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q05682	CALD1	P27361	MAPK3	T730	T735I	735	Missense	distal	5	no	13.698	13.441	EPSD	CCLE	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P14598	NCF1	P27361	MAPK3	S348	R354L	354	Missense	distal	6	no	18.072	17.957	PhosphoSitePlus;EPSD	CCLE	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q92934	BAD	P27361	MAPK3	S25	S32L	32	Missense	distal	7	no	18.920	19.190	EPSD	CCLE	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q92934	BAD	P27361	MAPK3	S75	H73Q	73	Missense	proximal	-2	no	11.801	11.265	PhosphoSitePlus	CCLE	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q92934	BAD	P27361	MAPK3	S75	R70W	70	Missense	distal	-5	no	11.801	11.647	PhosphoSitePlus	CCLE	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q9H8Y8	GORASP2	P27361	MAPK3	T415	K420N	420	Missense	distal	5	no	13.920	13.950	EPSD	CCLE	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q9H8Y8	GORASP2	P27361	MAPK3	S432	V435L	435	Missense	distal	3	no	11.605	11.610	EPSD	CCLE	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q9H8Y8	GORASP2	P27361	MAPK3	S432	K438R	438	Missense	distal	6	no	11.605	11.571	EPSD	CCLE	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q9H8Y8	GORASP2	P27361	MAPK3	T433	V435L	435	Missense	proximal	2	no	18.295	18.297	EPSD	CCLE	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q9H8Y8	GORASP2	P27361	MAPK3	T433	K438R	438	Missense	distal	5	no	18.295	18.303	EPSD	CCLE	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q9H8Y8	GORASP2	P27361	MAPK3	S436	V435L	435	Missense	proximal	-1	no	11.768	11.763	EPSD	CCLE	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q9H8Y8	GORASP2	P27361	MAPK3	S436	K438R	438	Missense	proximal	2	no	11.768	11.772	EPSD	CCLE	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q9H8Y8	GORASP2	P27361	MAPK3	S436	S441C	441	Missense	distal	5	no	11.768	11.245	EPSD	CCLE	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q9H8Y8	GORASP2	P27361	MAPK3	S441	V435L	435	Missense	distal	-6	no	10.611	10.609	EPSD	CCLE	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q9H8Y8	GORASP2	P27361	MAPK3	S441	K438R	438	Missense	distal	-3	no	10.611	10.624	EPSD	CCLE	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q9H8Y8	GORASP2	P27361	MAPK3	S441	S441C	441	Missense	central	0	yes	10.611	0.000	EPSD	CCLE	9.358	Loss
CMGC_MAPK_ERK1_MAPK3_ST	P19793	RXRA	P27361	MAPK3	S21	R25Q	25	Missense	distal	4	no	18.489	18.444	EPSD	CCLE	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P19793	RXRA	P27361	MAPK3	S49	S52I	52	Missense	distal	3	no	16.919	16.867	EPSD	CCLE	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P19793	RXRA	P27361	MAPK3	T82	M77I	77	Missense	distal	-5	no	16.644	16.668	EPSD	CCLE	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P19793	RXRA	P27361	MAPK3	S225	N227S	227	Missense	proximal	2	no	9.861	9.879	EPSD	CCLE	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q8WX93	PALLD	P27361	MAPK3	S115	R120M	120	Missense	distal	5	no	16.440	16.193	EPSD	CCLE	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q8WX93	PALLD	P27361	MAPK3	S125	R120M	120	Missense	distal	-5	no	14.755	14.682	EPSD	CCLE	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q8WX93	PALLD	P27361	MAPK3	S192	E196Q	196	Missense	distal	4	no	13.583	13.492	EPSD	CCLE	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q8WX93	PALLD	P27361	MAPK3	S199	E196Q	196	Missense	distal	-3	no	15.780	15.754	EPSD	CCLE	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q8WX93	PALLD	P27361	MAPK3	S222	E229D	229	Missense	distal	7	no	17.496	17.498	EPSD	CCLE	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q8WX93	PALLD	P27361	MAPK3	S236	E229D	229	Missense	distal	-7	no	13.902	13.913	EPSD	CCLE	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q9UBN7	HDAC6	P27361	MAPK3	T1021	I1019V	1019	Missense	proximal	-2	no	15.977	16.161	EPSD	CCLE	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P50616	TOB1	P27361	MAPK3	S205	V201F	201	Missense	distal	-4	no	16.223	16.186	EPSD	CCLE	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P49815	TSC2	P27361	MAPK3	S540	R537P	537	Missense	distal	-3	no	16.225	16.271	EPSD	CCLE	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P49815	TSC2	P27361	MAPK3	S540	S538F	538	Missense	proximal	-2	no	16.225	14.925	EPSD	CCLE	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P49815	TSC2	P27361	MAPK3	S664	S660N	660	Missense	distal	-4	no	18.206	18.145	PhosphoSitePlus	CCLE	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P49815	TSC2	P27361	MAPK3	S1002	L995I	995	Missense	distal	-7	no	9.362	9.409	EPSD	CCLE	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P49815	TSC2	P27361	MAPK3	S1002	N1006S	1006	Missense	distal	4	no	9.362	9.509	EPSD	CCLE	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P49815	TSC2	P27361	MAPK3	S1411	A1416V	1416	Missense	distal	5	no	15.709	15.697	EPSD	CCLE	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P49815	TSC2	P27361	MAPK3	S1452	P1458T	1458	Missense	distal	6	no	17.941	17.916	EPSD	CCLE	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P49815	TSC2	P27361	MAPK3	S1464	P1458T	1458	Missense	distal	-6	no	9.946	9.863	EPSD	CCLE	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P10415	BCL2	P27361	MAPK3	S70	Q73H	73	Missense	distal	3	no	17.225	17.233	EPSD	CCLE	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P10415	BCL2	P27361	MAPK3	T74	Q73H	73	Missense	proximal	-1	no	17.429	17.471	PhosphoSitePlus;EPSD	CCLE	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P10415	BCL2	P27361	MAPK3	S87	V92L	92	Missense	distal	5	no	13.964	13.960	EPSD;PhosphoSitePlus	CCLE	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P10415	BCL2	P27361	MAPK3	S87	P88R	88	Missense	proximal	1	no	13.964	4.463	EPSD;PhosphoSitePlus	CCLE	9.358	Loss
CMGC_MAPK_ERK1_MAPK3_ST	P10415	BCL2	P27361	MAPK3	S87	A82T	82	Missense	distal	-5	no	13.964	14.047	EPSD;PhosphoSitePlus	CCLE	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q9NQ66	PLCB1	P27361	MAPK3	S501	P502I	502	Missense	proximal	1	no	17.376	7.869	EPSD	CCLE	9.358	Loss
CMGC_MAPK_ERK1_MAPK3_ST	Q9NQ66	PLCB1	P27361	MAPK3	S918	Q916H	916	Missense	proximal	-2	no	9.109	9.645	EPSD	CCLE	9.358	Gain
CMGC_MAPK_ERK1_MAPK3_ST	Q13950	RUNX2	P27361	MAPK3	S28	S32R	32	Missense	distal	4	no	16.754	16.607	EPSD;PhosphoSitePlus	CCLE	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q13950	RUNX2	P27361	MAPK3	S118	C123Y	123	Missense	distal	5	no	17.239	17.546	EPSD	CCLE	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q13950	RUNX2	P27361	MAPK3	S294	A291T	291	Missense	distal	-3	no	14.564	14.625	EPSD;PhosphoSitePlus	CCLE	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q13950	RUNX2	P27361	MAPK3	S294	Q301K	301	Missense	distal	7	no	14.564	14.540	EPSD;PhosphoSitePlus	CCLE	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q13950	RUNX2	P27361	MAPK3	S298	A291T	291	Missense	distal	-7	no	9.480	9.407	EPSD	CCLE	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q13950	RUNX2	P27361	MAPK3	S298	Q301K	301	Missense	distal	3	no	9.480	9.479	EPSD	CCLE	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q13950	RUNX2	P27361	MAPK3	S302	Q301K	301	Missense	proximal	-1	no	10.485	10.510	EPSD	CCLE	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q13950	RUNX2	P27361	MAPK3	S305	Q301K	301	Missense	distal	-4	no	10.376	10.359	EPSD	CCLE	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q13950	RUNX2	P27361	MAPK3	S465	P460L	460	Missense	distal	-5	no	15.290	15.236	EPSD	CCLE	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q13950	RUNX2	P27361	MAPK3	S465	L470V	470	Missense	distal	5	no	15.290	15.295	EPSD	CCLE	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P17655	CAPN2	P27361	MAPK3	S50	T44A	44	Missense	distal	-6	no	11.625	11.477	PhosphoSitePlus	CCLE	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P28324	ELK4	P27361	MAPK3	S180	P181S	181	Missense	proximal	1	no	17.767	8.714	EPSD	CCLE	9.358	Loss
CMGC_MAPK_ERK1_MAPK3_ST	P28324	ELK4	P27361	MAPK3	S180	S180Y	180	Missense	central	0	yes	17.767	0.000	EPSD	CCLE	9.358	Loss
CMGC_MAPK_ERK1_MAPK3_ST	P28324	ELK4	P27361	MAPK3	T185	P181S	181	Missense	distal	-4	no	14.448	14.475	EPSD	CCLE	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P28324	ELK4	P27361	MAPK3	T185	S180Y	180	Missense	distal	-5	no	14.448	14.384	EPSD	CCLE	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P28324	ELK4	P27361	MAPK3	T420	S413F	413	Missense	distal	-7	no	18.224	18.443	EPSD	CCLE	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	O75030	MITF	P27361	MAPK3	T23	K22Q	22	Missense	proximal	-1	no	11.407	11.381	EPSD	CCLE	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	O75030	MITF	P27361	MAPK3	T23	K22E	22	Missense	proximal	-1	no	11.407	11.437	EPSD	CCLE	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	O75030	MITF	P27361	MAPK3	S175	G174R	174	Missense	proximal	-1	no	10.252	10.276	EPSD	CCLE	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	O75030	MITF	P27361	MAPK3	S180	G174R	174	Missense	distal	-6	no	20.188	20.089	EPSD	CCLE	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	O75030	MITF	P27361	MAPK3	S491	S491F	491	Missense	central	0	yes	15.940	0.000	EPSD	CCLE	9.358	Loss
CMGC_MAPK_ERK1_MAPK3_ST	O75030	MITF	P27361	MAPK3	T510	S512N	512	Missense	proximal	2	no	10.527	10.510	EPSD	CCLE	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	O75030	MITF	P27361	MAPK3	S511	S512N	512	Missense	proximal	1	no	9.833	4.798	EPSD	CCLE	9.358	Loss
CMGC_MAPK_ERK1_MAPK3_ST	O75030	MITF	P27361	MAPK3	S512	S512N	512	Missense	central	0	yes	10.216	0.000	EPSD	CCLE	9.358	Loss
CMGC_MAPK_ERK1_MAPK3_ST	O75030	MITF	P27361	MAPK3	S515	S512N	512	Missense	distal	-3	no	10.739	10.695	EPSD	CCLE	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P03372	ESR1	P27361	MAPK3	S104	F97S	97	Missense	distal	-7	no	16.662	16.443	EPSD;PhosphoSitePlus	CCLE	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P03372	ESR1	P27361	MAPK3	S294	M297I	297	Missense	distal	3	no	14.592	14.602	EPSD	CCLE	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q13614	MTMR2	P27361	MAPK3	S58	P59H	59	Missense	proximal	1	no	14.679	6.923	PhosphoSitePlus	CCLE	9.358	Loss
CMGC_MAPK_ERK1_MAPK3_ST	Q13614	MTMR2	P27361	MAPK3	S558	Y565F	565	Missense	distal	7	no	10.270	10.506	EPSD	CCLE	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P41212	ETV6	P27361	MAPK3	T4	C8S	8	Missense	distal	4	no	13.152	13.656	EPSD	CCLE	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P41212	ETV6	P27361	MAPK3	T4	I10V	10	Missense	distal	6	no	13.152	13.283	EPSD	CCLE	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P41212	ETV6	P27361	MAPK3	S16	I10V	10	Missense	distal	-6	no	10.814	10.883	EPSD	CCLE	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P41212	ETV6	P27361	MAPK3	T161	E154Q	154	Missense	distal	-7	no	13.998	14.048	EPSD	CCLE	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P41212	ETV6	P27361	MAPK3	S184	R183G	183	Missense	proximal	-1	no	16.650	16.626	EPSD	CCLE	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P19419	ELK1	P27361	MAPK3	T336	S339L	339	Missense	distal	3	no	15.581	15.549	EPSD	CCLE	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P19419	ELK1	P27361	MAPK3	T353	P358H	358	Missense	distal	5	no	14.553	14.489	EPSD	CCLE	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P19419	ELK1	P27361	MAPK3	T363	T368P	368	Missense	distal	5	no	16.703	16.795	EPSD	CCLE	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P19419	ELK1	P27361	MAPK3	T363	P358H	358	Missense	distal	-5	no	16.703	16.671	EPSD	CCLE	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P19419	ELK1	P27361	MAPK3	T368	T368P	368	Missense	central	0	yes	13.845	0.000	EPSD	CCLE	9.358	Loss
CMGC_MAPK_ERK1_MAPK3_ST	P19419	ELK1	P27361	MAPK3	S383	A386V	386	Missense	distal	3	no	16.736	16.743	EPSD;PhosphoSitePlus	CCLE	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P19419	ELK1	P27361	MAPK3	S389	A386V	386	Missense	distal	-3	no	16.106	16.125	PhosphoSitePlus;EPSD	CCLE	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P19419	ELK1	P27361	MAPK3	S411	P408S	408	Missense	distal	-3	no	10.146	10.138	EPSD	CCLE	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P12980	LYL1	P27361	MAPK3	S36	A35V	35	Missense	proximal	-1	no	17.023	17.072	PhosphoSitePlus	CCLE	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P12980	LYL1	P27361	MAPK3	S260	P257S	257	Missense	distal	-3	no	19.473	19.465	EPSD	CCLE	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P08047	SP1	P27361	MAPK3	S41	G44S	44	Missense	distal	3	no	10.038	10.054	EPSD	CCLE	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P08047	SP1	P27361	MAPK3	S42	G44S	44	Missense	proximal	2	no	10.411	10.428	EPSD	CCLE	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P08047	SP1	P27361	MAPK3	S46	G44S	44	Missense	proximal	-2	no	8.850	9.891	EPSD	CCLE	9.358	Gain
CMGC_MAPK_ERK1_MAPK3_ST	P08047	SP1	P27361	MAPK3	T278	V284G	284	Missense	distal	6	no	14.656	14.862	EPSD	CCLE	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P55211	CASP9	P27361	MAPK3	S87	M84T	84	Missense	distal	-3	no	12.012	12.109	EPSD	CCLE	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P55211	CASP9	P27361	MAPK3	T125	R122K	122	Missense	distal	-3	no	16.610	16.597	PhosphoSitePlus	CCLE	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	O43561	LAT	P27361	MAPK3	S35	S41L	41	Missense	distal	6	no	10.171	9.814	EPSD	CCLE	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	O43561	LAT	P27361	MAPK3	S74	Y70S	70	Missense	distal	-4	no	9.977	10.080	EPSD	CCLE	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q15788	NCOA1	P27361	MAPK3	S97	Q95K	95	Missense	proximal	-2	no	9.649	9.073	EPSD	CCLE	9.358	Loss
CMGC_MAPK_ERK1_MAPK3_ST	Q15788	NCOA1	P27361	MAPK3	S372	H368D	368	Missense	distal	-4	no	16.818	16.846	EPSD	CCLE	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q15788	NCOA1	P27361	MAPK3	S372	T377N	377	Missense	distal	5	no	16.818	16.832	EPSD	CCLE	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q15788	NCOA1	P27361	MAPK3	S372	T377S	377	Missense	distal	5	no	16.818	16.954	EPSD	CCLE	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q15788	NCOA1	P27361	MAPK3	S488	Q492L	492	Missense	distal	4	no	15.305	15.293	EPSD	CCLE	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q15788	NCOA1	P27361	MAPK3	S558	S555C	555	Missense	distal	-3	no	14.632	14.454	EPSD	CCLE	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q15788	NCOA1	P27361	MAPK3	T763	E757A	757	Missense	distal	-6	no	14.531	14.231	EPSD	CCLE	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q96RK0	CIC	P27361	MAPK3	S12	H5Y	5	Missense	distal	-7	no	11.236	11.283	EPSD	CCLE	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q96RK0	CIC	P27361	MAPK3	S105	P103S	103	Missense	proximal	-2	no	18.171	17.095	EPSD	CCLE	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q96RK0	CIC	P27361	MAPK3	S349	P352L	352	Missense	distal	3	no	9.953	9.917	EPSD	CCLE	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q96RK0	CIC	P27361	MAPK3	S349	P352R	352	Missense	distal	3	no	9.953	9.927	EPSD	CCLE	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q96RK0	CIC	P27361	MAPK3	S700	S694C	694	Missense	distal	-6	no	15.564	15.005	EPSD	CCLE	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q96RK0	CIC	P27361	MAPK3	S904	P897T	897	Missense	distal	-7	no	16.255	16.294	EPSD	CCLE	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q96RK0	CIC	P27361	MAPK3	S1595	P1596R	1596	Missense	proximal	1	no	18.888	9.387	EPSD	CCLE	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q92793	CREBBP	P27361	MAPK3	T974	P975L	975	Missense	proximal	1	no	13.887	4.849	EPSD	CCLE	9.358	Loss
CMGC_MAPK_ERK1_MAPK3_ST	Q92793	CREBBP	P27361	MAPK3	S1763	Q1760E	1760	Missense	distal	-3	no	17.993	18.019	EPSD	CCLE	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q92793	CREBBP	P27361	MAPK3	S1912	S1917A	1917	Missense	distal	5	no	16.281	16.025	EPSD	CCLE	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q01196	RUNX1	P27361	MAPK3	S67	N69K	69	Missense	proximal	2	no	17.053	17.054	EPSD	CCLE	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q01196	RUNX1	P27361	MAPK3	S249	T243A	243	Missense	distal	-6	no	15.212	15.064	EPSD	CCLE	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q01196	RUNX1	P27361	MAPK3	S276	G282D	282	Missense	distal	6	no	17.718	17.774	PhosphoSitePlus;EPSD	CCLE	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q01196	RUNX1	P27361	MAPK3	S386	A384S	384	Missense	proximal	-2	no	8.212	9.487	EPSD	CCLE	9.358	Gain
CMGC_MAPK_ERK1_MAPK3_ST	Q01860	POU5F1	P27361	MAPK3	T118	P119S	119	Missense	proximal	1	no	16.550	7.496	EPSD	CCLE	9.358	Loss
CMGC_MAPK_ERK1_MAPK3_ST	P23396	RPS3	P27361	MAPK3	T221	K227R	227	Missense	distal	6	no	19.601	19.567	EPSD	CCLE	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P23396	RPS3	P27361	MAPK3	S224	K227R	227	Missense	distal	3	no	11.691	11.693	EPSD	CCLE	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P17861	XBP1	P27361	MAPK3	T14	P15S	15	Missense	proximal	1	no	14.755	5.702	EPSD	CCLE	9.358	Loss
CMGC_MAPK_ERK1_MAPK3_ST	P17861	XBP1	P27361	MAPK3	S255	R251P	251	Missense	distal	-4	no	10.729	10.779	EPSD	CCLE	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q8IZP0	ABI1	P27361	MAPK3	S22	A18T	18	Missense	distal	-4	no	10.338	10.411	EPSD	CCLE	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q8IZP0	ABI1	P27361	MAPK3	S410	P416L	416	Missense	distal	6	no	16.907	16.680	PhosphoSitePlus;EPSD	CCLE	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P35658	NUP214	P27361	MAPK3	S483	A478V	478	Missense	distal	-5	no	10.983	11.006	EPSD	CCLE	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P35658	NUP214	P27361	MAPK3	S483	V481M	481	Missense	proximal	-2	no	10.983	9.883	EPSD	CCLE	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P35658	NUP214	P27361	MAPK3	T519	P525S	525	Missense	distal	6	no	11.920	12.050	EPSD	CCLE	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P35658	NUP214	P27361	MAPK3	T533	A535V	535	Missense	proximal	2	no	14.038	14.051	EPSD	CCLE	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P35658	NUP214	P27361	MAPK3	S537	A535V	535	Missense	proximal	-2	no	15.176	15.873	EPSD	CCLE	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P35658	NUP214	P27361	MAPK3	S666	A673T	673	Missense	distal	7	no	17.714	17.487	EPSD	CCLE	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P35658	NUP214	P27361	MAPK3	T670	A673T	673	Missense	distal	3	no	13.880	13.911	EPSD	CCLE	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P35658	NUP214	P27361	MAPK3	S678	A673T	673	Missense	distal	-5	no	16.323	16.406	EPSD	CCLE	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P35658	NUP214	P27361	MAPK3	T1156	A1159T	1159	Missense	distal	3	no	14.200	14.230	EPSD	CCLE	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P35658	NUP214	P27361	MAPK3	T1178	Q1183H	1183	Missense	distal	5	no	12.304	12.341	EPSD	CCLE	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P35658	NUP214	P27361	MAPK3	S1272	P1269L	1269	Missense	distal	-3	no	16.201	16.117	EPSD	CCLE	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P35658	NUP214	P27361	MAPK3	S1978	G1971D	1971	Missense	distal	-7	no	15.610	15.615	EPSD	CCLE	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q15672	TWIST1	P27361	MAPK3	S8	S6C	6	Missense	proximal	-2	no	14.982	12.542	EPSD	CCLE	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q15672	TWIST1	P27361	MAPK3	S8	D4E	4	Missense	distal	-4	no	14.982	14.993	EPSD	CCLE	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q15672	TWIST1	P27361	MAPK3	S11	S6C	6	Missense	distal	-5	no	16.222	16.060	EPSD	CCLE	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q15672	TWIST1	P27361	MAPK3	S11	D4E	4	Missense	distal	-7	no	16.222	16.212	EPSD	CCLE	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q15672	TWIST1	P27361	MAPK3	S20	P24A	24	Missense	distal	4	no	9.358	9.076	EPSD	CCLE	9.358	Loss
CMGC_MAPK_ERK1_MAPK3_ST	Q15672	TWIST1	P27361	MAPK3	S20	E22A	22	Missense	proximal	2	no	9.358	9.328	EPSD	CCLE	9.358	Loss
CMGC_MAPK_ERK1_MAPK3_ST	P28562	DUSP1	P27361	MAPK3	S359	S364Y	364	Missense	distal	5	no	18.543	18.327	EPSD;PhosphoSitePlus	CCLE	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P28562	DUSP1	P27361	MAPK3	S364	S364Y	364	Missense	central	0	yes	19.350	0.000	PhosphoSitePlus;EPSD	CCLE	9.358	Loss
CMGC_MAPK_ERK1_MAPK3_ST	Q92974	ARHGEF2	P27361	MAPK3	S163	R168H	168	Missense	distal	5	no	16.999	17.035	EPSD	CCLE	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q92974	ARHGEF2	P27361	MAPK3	S172	R168H	168	Missense	distal	-4	no	9.741	9.755	EPSD	CCLE	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q92974	ARHGEF2	P27361	MAPK3	T455	A453T	453	Missense	proximal	-2	no	12.419	13.784	EPSD	CCLE	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q92974	ARHGEF2	P27361	MAPK3	S645	L646P	646	Missense	proximal	1	no	7.663	16.701	EPSD	CCLE	9.358	Gain
CMGC_MAPK_ERK1_MAPK3_ST	Q92974	ARHGEF2	P27361	MAPK3	S648	L646P	646	Missense	proximal	-2	no	17.806	19.190	EPSD	CCLE	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q92974	ARHGEF2	P27361	MAPK3	S648	R642S	642	Missense	distal	-6	no	17.806	17.966	EPSD	CCLE	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q92974	ARHGEF2	P27361	MAPK3	S696	G692S	692	Missense	distal	-4	no	15.941	15.979	EPSD	CCLE	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q92974	ARHGEF2	P27361	MAPK3	S932	G931E	931	Missense	proximal	-1	no	14.564	14.605	EPSD	CCLE	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q15796	SMAD2	P27361	MAPK3	T172	L179S	179	Missense	distal	7	no	13.836	13.566	EPSD	CCLE	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q15796	SMAD2	P27361	MAPK3	S250	L254F	254	Missense	distal	4	no	17.689	17.478	EPSD;PhosphoSitePlus	CCLE	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q15796	SMAD2	P27361	MAPK3	T253	L254F	254	Missense	proximal	1	no	8.595	11.419	EPSD	CCLE	9.358	Gain
CMGC_MAPK_ERK1_MAPK3_ST	Q15796	SMAD2	P27361	MAPK3	S255	L254F	254	Missense	proximal	-1	no	18.277	18.162	PhosphoSitePlus;EPSD	CCLE	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P16144	ITGB4	P27361	MAPK3	S99	G105D	105	Missense	distal	6	no	9.797	9.853	EPSD	CCLE	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P16144	ITGB4	P27361	MAPK3	S102	G105D	105	Missense	distal	3	no	16.331	16.336	EPSD	CCLE	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P16144	ITGB4	P27361	MAPK3	S102	R107Q	107	Missense	distal	5	no	16.331	16.329	EPSD	CCLE	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P16144	ITGB4	P27361	MAPK3	S397	F390S	390	Missense	distal	-7	no	9.948	9.729	EPSD	CCLE	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P16144	ITGB4	P27361	MAPK3	S397	E404G	404	Missense	distal	7	no	9.948	9.983	EPSD	CCLE	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	O95817	BAG3	P27361	MAPK3	S7	A4T	4	Missense	distal	-3	no	16.326	16.387	EPSD	CCLE	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	O95817	BAG3	P27361	MAPK3	S7	S7P	7	Missense	central	0	yes	16.326	0.000	EPSD	CCLE	9.358	Loss
CMGC_MAPK_ERK1_MAPK3_ST	O95817	BAG3	P27361	MAPK3	S264	P259L	259	Missense	distal	-5	no	13.797	13.742	EPSD	CCLE	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	O95817	BAG3	P27361	MAPK3	S279	A273T	273	Missense	distal	-6	no	16.045	16.193	EPSD	CCLE	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	O95817	BAG3	P27361	MAPK3	S279	E277V	277	Missense	proximal	-2	no	16.045	16.036	EPSD	CCLE	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	O95817	BAG3	P27361	MAPK3	S284	E277V	277	Missense	distal	-7	no	9.560	9.677	EPSD	CCLE	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	O95817	BAG3	P27361	MAPK3	S284	S289P	289	Missense	distal	5	no	9.560	9.517	EPSD	CCLE	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	O95817	BAG3	P27361	MAPK3	T285	S289P	289	Missense	distal	4	no	16.402	16.353	PhosphoSitePlus;EPSD	CCLE	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	O95817	BAG3	P27361	MAPK3	S289	S289P	289	Missense	central	0	yes	16.568	0.000	EPSD;PhosphoSitePlus	CCLE	9.358	Loss
CMGC_MAPK_ERK1_MAPK3_ST	O95817	BAG3	P27361	MAPK3	S291	S289P	289	Missense	proximal	-2	no	17.901	18.977	EPSD	CCLE	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	O95817	BAG3	P27361	MAPK3	T406	G411V	411	Missense	distal	5	no	13.749	13.547	EPSD	CCLE	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q15648	MED1	P27361	MAPK3	S887	E881G	881	Missense	distal	-6	no	9.678	9.632	EPSD	CCLE	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q15648	MED1	P27361	MAPK3	S1453	T1457P	1457	Missense	distal	4	no	17.235	17.299	EPSD	CCLE	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q15648	MED1	P27361	MAPK3	T1457	T1457P	1457	Missense	central	0	yes	14.176	0.000	PhosphoSitePlus;EPSD	CCLE	9.358	Loss
CMGC_MAPK_ERK1_MAPK3_ST	O15027	SEC16A	P27361	MAPK3	S383	D389N	389	Missense	distal	6	no	9.968	9.915	EPSD	CCLE	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	O15027	SEC16A	P27361	MAPK3	S391	P392L	392	Missense	proximal	1	no	16.022	6.984	EPSD	CCLE	9.358	Loss
CMGC_MAPK_ERK1_MAPK3_ST	O15027	SEC16A	P27361	MAPK3	S391	D389N	389	Missense	proximal	-2	no	16.022	15.609	EPSD	CCLE	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	O15027	SEC16A	P27361	MAPK3	S432	S428I	428	Missense	distal	-4	no	12.316	12.157	EPSD	CCLE	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	O15027	SEC16A	P27361	MAPK3	S1663	S1668G	1668	Missense	distal	5	no	16.551	16.486	EPSD	CCLE	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	O15027	SEC16A	P27361	MAPK3	S1844	S1844R	1844	Missense	central	0	yes	16.566	0.000	EPSD	CCLE	9.358	Loss
CMGC_MAPK_ERK1_MAPK3_ST	O15027	SEC16A	P27361	MAPK3	S1905	T1898K	1898	Missense	distal	-7	no	18.669	18.676	EPSD	CCLE	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	O15027	SEC16A	P27361	MAPK3	T1980	A1974T	1974	Missense	distal	-6	no	9.506	9.654	EPSD	CCLE	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	O15027	SEC16A	P27361	MAPK3	T2053	N2048H	2048	Missense	distal	-5	no	13.944	13.949	EPSD	CCLE	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q9NRA0	SPHK2	P27361	MAPK3	S473	S477F	477	Missense	distal	4	no	16.344	15.929	EPSD	CCLE	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q9NRA0	SPHK2	P27361	MAPK3	S477	S477F	477	Missense	central	0	yes	17.035	0.000	EPSD	CCLE	9.358	Loss
CMGC_MAPK_ERK1_MAPK3_ST	Q9NRA0	SPHK2	P27361	MAPK3	S484	S477F	477	Missense	distal	-7	no	17.628	17.847	EPSD	CCLE	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q03060	CREM	P27361	MAPK3	S290	Q295H	295	Missense	distal	5	no	9.745	9.782	EPSD	CCLE	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q03060	CREM	P27361	MAPK3	S293	Q295H	295	Missense	proximal	2	no	14.622	14.629	EPSD	CCLE	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q00613	HSF1	P27361	MAPK3	S244	P243L	243	Missense	proximal	-1	no	15.761	15.666	EPSD	CCLE	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q00613	HSF1	P27361	MAPK3	S292	R287M	287	Missense	distal	-5	no	16.604	16.532	EPSD	CCLE	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q00613	HSF1	P27361	MAPK3	T369	E371K	371	Missense	proximal	2	no	15.694	15.686	EPSD	CCLE	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q00613	HSF1	P27361	MAPK3	S419	V424M	424	Missense	distal	5	no	15.478	15.353	EPSD	CCLE	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q00613	HSF1	P27361	MAPK3	S498	G495E	495	Missense	distal	-3	no	9.746	9.759	EPSD	CCLE	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q00613	HSF1	P27361	MAPK3	S498	F500Y	500	Missense	proximal	2	no	9.746	9.775	EPSD	CCLE	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q00613	HSF1	P27361	MAPK3	S518	A523D	523	Missense	distal	5	no	10.477	10.690	EPSD	CCLE	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q9UIG0	BAZ1B	P27361	MAPK3	S330	K335Q	335	Missense	distal	5	no	17.584	17.591	EPSD	CCLE	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q9UIG0	BAZ1B	P27361	MAPK3	S361	K360T	360	Missense	proximal	-1	no	16.637	16.662	EPSD	CCLE	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q9ULV5	HSF4	P27361	MAPK3	S40	D34N	34	Missense	distal	-6	no	13.622	13.560	EPSD	CCLE	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q8N122	RPTOR	P27361	MAPK3	S8	E2Q	2	Missense	distal	-6	no	16.132	15.997	EPSD;PhosphoSitePlus	CCLE	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q8N122	RPTOR	P27361	MAPK3	S898	R899Q	899	Missense	proximal	1	no	8.814	10.371	EPSD	CCLE	9.358	Gain
CMGC_MAPK_ERK1_MAPK3_ST	P49407	ARRB1	P27361	MAPK3	S86	V84A	84	Missense	proximal	-2	no	10.307	9.610	EPSD	CCLE	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P49407	ARRB1	P27361	MAPK3	S412	N416T	416	Missense	distal	4	no	19.354	19.388	PhosphoSitePlus	CCLE	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P33076	CIITA	P27361	MAPK3	S280	R283W	283	Missense	distal	3	no	19.345	19.267	PhosphoSitePlus;EPSD	CCLE	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P33076	CIITA	P27361	MAPK3	S288	R283W	283	Missense	distal	-5	no	16.051	15.897	EPSD;PhosphoSitePlus	CCLE	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P33076	CIITA	P27361	MAPK3	S834	L833P	833	Missense	proximal	-1	no	9.295	9.389	EPSD	CCLE	9.358	Gain
CMGC_MAPK_ERK1_MAPK3_ST	P33076	CIITA	P27361	MAPK3	S942	S944L	944	Missense	proximal	2	no	9.374	9.351	EPSD	CCLE	9.358	Loss
CMGC_MAPK_ERK1_MAPK3_ST	P33076	CIITA	P27361	MAPK3	S942	D946N	946	Missense	distal	4	no	9.374	9.347	EPSD	CCLE	9.358	Loss
CMGC_MAPK_ERK1_MAPK3_ST	P78347	GTF2I	P27361	MAPK3	S210	S207P	207	Missense	distal	-3	no	15.908	15.916	EPSD	CCLE	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P78347	GTF2I	P27361	MAPK3	S515	G520E	520	Missense	distal	5	no	15.756	15.797	EPSD	CCLE	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P78347	GTF2I	P27361	MAPK3	S620	G615R	615	Missense	distal	-5	no	16.076	16.073	EPSD	CCLE	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P78347	GTF2I	P27361	MAPK3	S620	S620R	620	Missense	central	0	yes	16.076	0.000	EPSD	CCLE	9.358	Loss
CMGC_MAPK_ERK1_MAPK3_ST	P78347	GTF2I	P27361	MAPK3	S651	G656E	656	Missense	distal	5	no	10.634	10.675	EPSD	CCLE	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P78347	GTF2I	P27361	MAPK3	T785	R781Q	781	Missense	distal	-4	no	10.596	10.607	EPSD	CCLE	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P78347	GTF2I	P27361	MAPK3	T785	P789L	789	Missense	distal	4	no	10.596	10.442	EPSD	CCLE	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P78347	GTF2I	P27361	MAPK3	T978	I981K	981	Missense	distal	3	no	11.815	11.843	EPSD	CCLE	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P78347	GTF2I	P27361	MAPK3	S988	I981K	981	Missense	distal	-7	no	11.089	10.982	EPSD	CCLE	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P78347	GTF2I	P27361	MAPK3	S988	I990N	990	Missense	proximal	2	no	11.089	11.107	EPSD	CCLE	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P78347	GTF2I	P27361	MAPK3	T997	I990N	990	Missense	distal	-7	no	9.521	9.397	EPSD	CCLE	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q9ULC4	MCTS1	P27361	MAPK3	S118	I111V	111	Missense	distal	-7	no	14.525	14.483	EPSD	CCLE	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q9ULC4	MCTS1	P27361	MAPK3	S118	G120R	120	Missense	proximal	2	no	14.525	14.529	EPSD	CCLE	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P42229	STAT5A	P27361	MAPK3	S128	E122K	122	Missense	distal	-6	no	12.917	12.775	EPSD	CCLE	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P42229	STAT5A	P27361	MAPK3	S777	D776A	776	Missense	proximal	-1	no	9.885	9.798	EPSD	CCLE	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P42229	STAT5A	P27361	MAPK3	S777	S777P	777	Missense	central	0	yes	9.885	0.000	EPSD	CCLE	9.358	Loss
CMGC_MAPK_ERK1_MAPK3_ST	P42229	STAT5A	P27361	MAPK3	S780	D776A	776	Missense	distal	-4	no	18.628	18.531	PhosphoSitePlus	CCLE	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P42229	STAT5A	P27361	MAPK3	S780	S777P	777	Missense	distal	-3	no	18.628	18.636	PhosphoSitePlus	CCLE	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q8N9N5	BANP	P27361	MAPK3	S90	I92T	92	Missense	proximal	2	no	14.270	14.294	EPSD	CCLE	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q8N9N5	BANP	P27361	MAPK3	S100	A98S	98	Missense	proximal	-2	no	16.242	17.517	EPSD	CCLE	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q8N9N5	BANP	P27361	MAPK3	S100	T107M	107	Missense	distal	7	no	16.242	16.574	EPSD	CCLE	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q8N9N5	BANP	P27361	MAPK3	T352	T352P	352	Missense	central	0	yes	14.465	0.000	EPSD;PhosphoSitePlus	CCLE	9.358	Loss
CMGC_MAPK_ERK1_MAPK3_ST	O00429	DNM1L	P27361	MAPK3	S544	S548P	548	Missense	distal	4	no	9.422	9.373	EPSD	CCLE	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	O00429	DNM1L	P27361	MAPK3	S548	S548P	548	Missense	central	0	yes	16.860	0.000	EPSD	CCLE	9.358	Loss
CMGC_MAPK_ERK1_MAPK3_ST	P17542	TAL1	P27361	MAPK3	S122	P124S	124	Missense	proximal	2	no	16.727	16.729	PhosphoSitePlus	CCLE	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P17542	TAL1	P27361	MAPK3	S122	G116S	116	Missense	distal	-6	no	16.727	16.790	PhosphoSitePlus	CCLE	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q13485	SMAD4	P27361	MAPK3	T277	T273I	273	Missense	distal	-4	no	16.892	16.791	PhosphoSitePlus	CCLE	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P00533	EGFR	P27361	MAPK3	S77	Q71L	71	Missense	distal	-6	no	10.908	10.728	EPSD	CCLE	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P63000	RAC1	P27361	MAPK3	S89	V85M	85	Missense	distal	-4	no	12.292	12.264	EPSD	CCLE	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P63000	RAC1	P27361	MAPK3	S89	S86I	86	Missense	distal	-3	no	12.292	12.180	EPSD	CCLE	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P63000	RAC1	P27361	MAPK3	S89	A88E	88	Missense	proximal	-1	no	12.292	12.401	EPSD	CCLE	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P63000	RAC1	P27361	MAPK3	S89	N92Y	92	Missense	distal	3	no	12.292	12.282	EPSD	CCLE	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	O60244	MED14	P27361	MAPK3	S151	F152C	152	Missense	proximal	1	no	10.021	0.927	EPSD	CCLE	9.358	Loss
CMGC_MAPK_ERK1_MAPK3_ST	P61978	HNRNPK	P27361	MAPK3	S116	T120I	120	Missense	distal	4	no	16.938	16.710	EPSD	CCLE	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P61978	HNRNPK	P27361	MAPK3	S216	R221C	221	Missense	distal	5	no	14.264	13.884	EPSD	CCLE	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P61978	HNRNPK	P27361	MAPK3	T440	R433G	433	Missense	distal	-7	no	11.582	11.537	EPSD	CCLE	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P29966	MARCKS	P27361	MAPK3	S27	A25T	25	Missense	proximal	-2	no	17.186	18.551	EPSD	CCLE	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P29966	MARCKS	P27361	MAPK3	S46	A50T	50	Missense	distal	4	no	15.205	15.423	PhosphoSitePlus	CCLE	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P29966	MARCKS	P27361	MAPK3	S81	A79V	79	Missense	proximal	-2	no	14.722	15.419	EPSD	CCLE	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P29966	MARCKS	P27361	MAPK3	S81	A84S	84	Missense	distal	3	no	14.722	14.766	EPSD	CCLE	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P29966	MARCKS	P27361	MAPK3	S101	A95G	95	Missense	distal	-6	no	14.914	15.168	EPSD	CCLE	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P29966	MARCKS	P27361	MAPK3	S101	E106K	106	Missense	distal	5	no	14.914	14.786	EPSD	CCLE	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P29966	MARCKS	P27361	MAPK3	S118	E123K	123	Missense	distal	5	no	17.485	17.357	EPSD	CCLE	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P29966	MARCKS	P27361	MAPK3	S118	E123A	123	Missense	distal	5	no	17.485	17.254	EPSD	CCLE	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P29966	MARCKS	P27361	MAPK3	S118	G124R	124	Missense	distal	6	no	17.485	17.476	EPSD	CCLE	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P29966	MARCKS	P27361	MAPK3	S135	P136L	136	Missense	proximal	1	no	17.009	7.971	EPSD	CCLE	9.358	Loss
CMGC_MAPK_ERK1_MAPK3_ST	P29966	MARCKS	P27361	MAPK3	T143	P136L	136	Missense	distal	-7	no	13.202	13.309	EPSD	CCLE	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P29966	MARCKS	P27361	MAPK3	T143	S145A	145	Missense	proximal	2	no	13.202	13.163	EPSD	CCLE	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P29966	MARCKS	P27361	MAPK3	S145	S145A	145	Missense	central	0	yes	16.801	0.000	EPSD	CCLE	9.358	Loss
CMGC_MAPK_ERK1_MAPK3_ST	P29966	MARCKS	P27361	MAPK3	T150	S145A	145	Missense	distal	-5	no	15.194	15.095	EPSD	CCLE	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	O43524	FOXO3	P27361	MAPK3	S26	R27G	27	Missense	proximal	1	no	11.724	9.685	EPSD	CCLE	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	O43524	FOXO3	P27361	MAPK3	S43	Q41K	41	Missense	proximal	-2	no	14.611	14.034	EPSD	CCLE	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	O43524	FOXO3	P27361	MAPK3	S161	D164N	164	Missense	distal	3	no	10.249	10.238	EPSD	CCLE	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	O43524	FOXO3	P27361	MAPK3	S446	R444C	444	Missense	proximal	-2	no	15.312	13.196	EPSD	CCLE	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	O43524	FOXO3	P27361	MAPK3	S667	P672S	672	Missense	distal	5	no	11.953	11.996	EPSD	CCLE	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	O43524	FOXO3	P27361	MAPK3	S669	P672S	672	Missense	distal	3	no	11.016	11.012	EPSD	CCLE	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q13115	DUSP4	P27361	MAPK3	S345	C339Y	339	Missense	distal	-6	no	15.420	15.726	EPSD	CCLE	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q9UHB6	LIMA1	P27361	MAPK3	S619	S622C	622	Missense	distal	3	no	9.465	9.380	EPSD	CCLE	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q9UHB6	LIMA1	P27361	MAPK3	S704	S709L	709	Missense	distal	5	no	10.127	9.856	EPSD	CCLE	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q05209	PTPN12	P27361	MAPK3	S323	S324P	324	Missense	proximal	1	no	6.919	15.972	EPSD	CCLE	9.358	Gain
CMGC_MAPK_ERK1_MAPK3_ST	Q05209	PTPN12	P27361	MAPK3	S588	T587P	587	Missense	proximal	-1	no	16.520	16.557	EPSD	CCLE	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q05209	PTPN12	P27361	MAPK3	T593	T587P	587	Missense	distal	-6	no	14.354	14.437	EPSD	CCLE	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q05209	PTPN12	P27361	MAPK3	T593	N599H	599	Missense	distal	6	no	14.354	14.360	EPSD	CCLE	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q05209	PTPN12	P27361	MAPK3	S596	N599H	599	Missense	distal	3	no	10.282	10.289	EPSD	CCLE	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q9UKX7	NUP50	P27361	MAPK3	S141	S147F	147	Missense	distal	6	no	9.603	8.889	EPSD	CCLE	9.358	Loss
CMGC_MAPK_ERK1_MAPK3_ST	Q9UKX7	NUP50	P27361	MAPK3	S142	S147F	147	Missense	distal	5	no	11.541	11.117	EPSD	CCLE	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q15746	MYLK	P27361	MAPK3	T978	V971A	971	Missense	distal	-7	no	18.294	18.295	EPSD	CCLE	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q15746	MYLK	P27361	MAPK3	S1208	K1207N	1207	Missense	proximal	-1	no	9.454	9.460	EPSD	CCLE	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q15746	MYLK	P27361	MAPK3	T1230	K1224M	1224	Missense	distal	-6	no	16.362	16.099	EPSD	CCLE	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q02447	SP3	P27361	MAPK3	S73	E78D	78	Missense	distal	5	no	18.394	18.376	PhosphoSitePlus	CCLE	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q02447	SP3	P27361	MAPK3	S73	P74L	74	Missense	proximal	1	no	18.394	9.356	PhosphoSitePlus	CCLE	9.358	Loss
CMGC_MAPK_ERK1_MAPK3_ST	Q02447	SP3	P27361	MAPK3	S544	H537Y	537	Missense	distal	-7	no	13.899	13.945	EPSD	CCLE	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q8IX03	WWC1	P27361	MAPK3	S270	S268G	268	Missense	proximal	-2	no	11.158	10.118	EPSD	CCLE	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q8IX03	WWC1	P27361	MAPK3	S358	P359L	359	Missense	proximal	1	no	15.901	6.863	EPSD	CCLE	9.358	Loss
CMGC_MAPK_ERK1_MAPK3_ST	Q8IX03	WWC1	P27361	MAPK3	S876	D880H	880	Missense	distal	4	no	14.104	14.084	EPSD	CCLE	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P14784	IL2RB	P27361	MAPK3	S431	S431F	431	Missense	central	0	yes	14.421	0.000	EPSD	CCLE	9.358	Loss
CMGC_MAPK_ERK1_MAPK3_ST	P14784	IL2RB	P27361	MAPK3	S458	M455I	455	Missense	distal	-3	no	9.727	9.743	EPSD	CCLE	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P14784	IL2RB	P27361	MAPK3	T476	T476M	476	Missense	central	0	yes	15.038	0.000	PhosphoSitePlus	CCLE	9.358	Loss
CMGC_MAPK_ERK1_MAPK3_ST	P06239	LCK	P27361	MAPK3	S75	H76R	76	Missense	proximal	1	no	9.553	7.808	EPSD	CCLE	9.358	Loss
CMGC_MAPK_ERK1_MAPK3_ST	P06239	LCK	P27361	MAPK3	S156	A160T	160	Missense	distal	4	no	10.064	10.282	EPSD	CCLE	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P06239	LCK	P27361	MAPK3	S162	A160T	160	Missense	proximal	-2	no	9.683	11.048	EPSD	CCLE	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P42702	LIFR	P27361	MAPK3	S534	P535T	535	Missense	proximal	1	no	17.155	8.278	EPSD	CCLE	9.358	Loss
CMGC_MAPK_ERK1_MAPK3_ST	P42702	LIFR	P27361	MAPK3	S534	T531A	531	Missense	distal	-3	no	17.155	17.094	EPSD	CCLE	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P42702	LIFR	P27361	MAPK3	T541	P535T	535	Missense	distal	-6	no	10.356	10.273	EPSD	CCLE	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P42702	LIFR	P27361	MAPK3	T904	E909K	909	Missense	distal	5	no	15.727	15.598	EPSD	CCLE	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P42702	LIFR	P27361	MAPK3	S1056	S1059N	1059	Missense	distal	3	no	11.583	11.562	EPSD	CCLE	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P42702	LIFR	P27361	MAPK3	S1059	S1059N	1059	Missense	central	0	yes	16.075	0.000	EPSD	CCLE	9.358	Loss
CMGC_MAPK_ERK1_MAPK3_ST	P42702	LIFR	P27361	MAPK3	S1062	S1059N	1059	Missense	distal	-3	no	11.245	11.201	EPSD	CCLE	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P62070	RRAS2	P27361	MAPK3	S186	P189L	189	Missense	distal	3	no	20.949	20.912	PhosphoSitePlus	CCLE	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q08499	PDE4D	P27361	MAPK3	S202	M206I	206	Missense	distal	4	no	16.308	16.346	EPSD	CCLE	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	O95644	NFATC1	P27361	MAPK3	S117	R119L	119	Missense	proximal	2	no	16.395	16.384	EPSD	CCLE	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	O95644	NFATC1	P27361	MAPK3	S117	T123N	123	Missense	distal	6	no	16.395	16.321	EPSD	CCLE	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	O95644	NFATC1	P27361	MAPK3	S172	S176I	176	Missense	distal	4	no	13.563	13.222	PhosphoSitePlus	CCLE	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	O95644	NFATC1	P27361	MAPK3	S172	S179P	179	Missense	distal	7	no	13.563	13.641	PhosphoSitePlus	CCLE	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	O95644	NFATC1	P27361	MAPK3	S175	S176I	176	Missense	proximal	1	no	9.388	8.934	EPSD	CCLE	9.358	Loss
CMGC_MAPK_ERK1_MAPK3_ST	O95644	NFATC1	P27361	MAPK3	S175	S179P	179	Missense	distal	4	no	9.388	9.339	EPSD	CCLE	9.358	Loss
CMGC_MAPK_ERK1_MAPK3_ST	O95644	NFATC1	P27361	MAPK3	S175	R180L	180	Missense	distal	5	no	9.388	9.261	EPSD	CCLE	9.358	Loss
CMGC_MAPK_ERK1_MAPK3_ST	O95644	NFATC1	P27361	MAPK3	S178	S179P	179	Missense	proximal	1	no	5.989	15.043	EPSD	CCLE	9.358	Gain
CMGC_MAPK_ERK1_MAPK3_ST	O95644	NFATC1	P27361	MAPK3	S211	S207F	207	Missense	distal	-4	no	13.644	13.455	EPSD	CCLE	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	O95644	NFATC1	P27361	MAPK3	S233	R235Q	235	Missense	proximal	2	no	16.952	16.943	EPSD	CCLE	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	O95644	NFATC1	P27361	MAPK3	S237	R235Q	235	Missense	proximal	-2	no	13.662	13.298	EPSD	CCLE	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	O95644	NFATC1	P27361	MAPK3	S237	R243C	243	Missense	distal	6	no	13.662	13.036	EPSD	CCLE	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	O95644	NFATC1	P27361	MAPK3	S241	R235Q	235	Missense	distal	-6	no	16.639	16.649	EPSD	CCLE	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	O95644	NFATC1	P27361	MAPK3	S241	R243C	243	Missense	proximal	2	no	16.639	16.590	EPSD	CCLE	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	O95644	NFATC1	P27361	MAPK3	S241	S245I	245	Missense	distal	4	no	16.639	16.298	EPSD	CCLE	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	O95644	NFATC1	P27361	MAPK3	S261	N264S	264	Missense	distal	3	no	16.253	16.274	EPSD	CCLE	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	O95644	NFATC1	P27361	MAPK3	S278	R273W	273	Missense	distal	-5	no	18.844	18.690	EPSD	CCLE	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	O95644	NFATC1	P27361	MAPK3	S282	P287S	287	Missense	distal	5	no	17.928	17.971	EPSD	CCLE	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	O95644	NFATC1	P27361	MAPK3	T284	P287S	287	Missense	distal	3	no	16.135	16.130	EPSD	CCLE	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	O95644	NFATC1	P27361	MAPK3	S286	P287S	287	Missense	proximal	1	no	14.954	5.901	EPSD	CCLE	9.358	Loss
CMGC_MAPK_ERK1_MAPK3_ST	O95644	NFATC1	P27361	MAPK3	S290	P287S	287	Missense	distal	-3	no	17.580	17.571	EPSD	CCLE	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	O95644	NFATC1	P27361	MAPK3	S359	G358V	358	Missense	proximal	-1	no	16.717	16.698	EPSD	CCLE	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	O95644	NFATC1	P27361	MAPK3	S403	Y407C	407	Missense	distal	4	no	17.502	17.214	EPSD	CCLE	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	O95644	NFATC1	P27361	MAPK3	S409	Y407C	407	Missense	proximal	-2	no	14.915	12.709	EPSD	CCLE	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	O95644	NFATC1	P27361	MAPK3	S670	V672A	672	Missense	proximal	2	no	17.270	17.257	EPSD	CCLE	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	O95644	NFATC1	P27361	MAPK3	S670	H673R	673	Missense	distal	3	no	17.270	17.262	EPSD	CCLE	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	O95644	NFATC1	P27361	MAPK3	S670	S675G	675	Missense	distal	5	no	17.270	17.205	EPSD	CCLE	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	O95644	NFATC1	P27361	MAPK3	S675	V672A	672	Missense	distal	-3	no	10.462	10.443	EPSD	CCLE	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	O95644	NFATC1	P27361	MAPK3	S675	H673R	673	Missense	proximal	-2	no	10.462	10.290	EPSD	CCLE	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	O95644	NFATC1	P27361	MAPK3	S675	S675G	675	Missense	central	0	yes	10.462	0.000	EPSD	CCLE	9.358	Loss
CMGC_MAPK_ERK1_MAPK3_ST	O95644	NFATC1	P27361	MAPK3	S772	T777P	777	Missense	distal	5	no	16.186	16.279	EPSD	CCLE	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	O95644	NFATC1	P27361	MAPK3	S782	T777P	777	Missense	distal	-5	no	16.229	16.239	EPSD	CCLE	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	O95644	NFATC1	P27361	MAPK3	S903	I909M	909	Missense	distal	6	no	16.396	16.317	EPSD	CCLE	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P04637	TP53	P27361	MAPK3	S33	E28Q	28	Missense	distal	-5	no	15.325	15.306	EPSD	CCLE	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P27708	CAD	P27361	MAPK3	T166	T172A	172	Missense	distal	6	no	13.797	13.426	EPSD	CCLE	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P27708	CAD	P27361	MAPK3	T456	Y459D	459	Missense	distal	3	no	16.501	16.521	PhosphoSitePlus	CCLE	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P27708	CAD	P27361	MAPK3	S586	A579D	579	Missense	distal	-7	no	10.028	9.921	EPSD	CCLE	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P10275	AR	P27361	MAPK3	S96	Q98R	98	Missense	proximal	2	no	16.503	16.512	EPSD	CCLE	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P13631	RARG	P27361	MAPK3	S452	L450M	450	Missense	proximal	-2	no	19.359	17.990	EPSD	CCLE	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P13631	RARG	P27361	MAPK3	S452	G448E	448	Missense	distal	-4	no	19.359	19.374	EPSD	CCLE	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P33981	TTK	P27361	MAPK3	S214	A211T	211	Missense	distal	-3	no	10.029	10.090	EPSD	CCLE	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P33981	TTK	P27361	MAPK3	S281	K287N	287	Missense	distal	6	no	17.437	17.416	EPSD	CCLE	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P33981	TTK	P27361	MAPK3	S582	D583N	583	Missense	proximal	1	no	9.807	4.320	EPSD	CCLE	9.358	Loss
CMGC_MAPK_ERK1_MAPK3_ST	O60331	PIP5K1C	P27361	MAPK3	S655	P660R	660	Missense	distal	5	no	9.580	9.479	EPSD	CCLE	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	O60331	PIP5K1C	P27361	MAPK3	S662	D667N	667	Missense	distal	5	no	12.268	12.188	EPSD	CCLE	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	O60331	PIP5K1C	P27361	MAPK3	S662	P660R	660	Missense	proximal	-2	no	12.268	10.868	EPSD	CCLE	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	O60331	PIP5K1C	P27361	MAPK3	S666	D667N	667	Missense	proximal	1	no	10.224	4.737	EPSD	CCLE	9.358	Loss
CMGC_MAPK_ERK1_MAPK3_ST	O60331	PIP5K1C	P27361	MAPK3	S666	P660R	660	Missense	distal	-6	no	10.224	10.148	EPSD	CCLE	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P27824	CANX	P27361	MAPK3	S583	S583P	583	Missense	central	0	yes	18.094	0.000	PhosphoSitePlus	CCLE	9.358	Loss
CMGC_MAPK_ERK1_MAPK3_ST	Q12931	TRAP1	P27361	MAPK3	S568	R567K	567	Missense	proximal	-1	no	12.835	12.822	EPSD	CCLE	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q92908	GATA6	P27361	MAPK3	T515	P513H	513	Missense	proximal	-2	no	18.227	17.000	EPSD	CCLE	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q92908	GATA6	P27361	MAPK3	T515	T517I	517	Missense	proximal	2	no	18.227	18.203	EPSD	CCLE	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q92797	SYMPK	P27361	MAPK3	S938	E932D	932	Missense	distal	-6	no	16.166	16.121	EPSD	CCLE	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q92797	SYMPK	P27361	MAPK3	S1081	H1085Y	1085	Missense	distal	4	no	9.423	9.348	EPSD	CCLE	9.358	Loss
CMGC_MAPK_ERK1_MAPK3_ST	Q92797	SYMPK	P27361	MAPK3	T1083	H1085Y	1085	Missense	proximal	2	no	16.399	16.393	EPSD	CCLE	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q92797	SYMPK	P27361	MAPK3	S1175	G1181D	1181	Missense	distal	6	no	18.048	18.104	EPSD	CCLE	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q9NRF2	SH2B1	P27361	MAPK3	S25	P21L	21	Missense	distal	-4	no	13.831	13.718	EPSD	CCLE	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q9NRF2	SH2B1	P27361	MAPK3	S96	E100D	100	Missense	distal	4	no	16.625	16.605	PhosphoSitePlus	CCLE	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q9NRF2	SH2B1	P27361	MAPK3	S102	E100D	100	Missense	proximal	-2	no	16.228	16.267	EPSD	CCLE	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q9NRF2	SH2B1	P27361	MAPK3	S384	M388V	388	Missense	distal	4	no	13.920	14.074	EPSD	CCLE	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P53355	DAPK1	P27361	MAPK3	T180	K175I	175	Missense	distal	-5	no	11.848	11.800	EPSD	CCLE	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P53355	DAPK1	P27361	MAPK3	T180	V184L	184	Missense	distal	4	no	11.848	11.868	EPSD	CCLE	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P53355	DAPK1	P27361	MAPK3	S321	F322Y	322	Missense	proximal	1	no	9.981	9.146	EPSD	CCLE	9.358	Loss
CMGC_MAPK_ERK1_MAPK3_ST	Q16254	E2F4	P27361	MAPK3	T14	A8V	8	Missense	distal	-6	no	17.274	17.261	EPSD	CCLE	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q16254	E2F4	P27361	MAPK3	T14	H18L	18	Missense	distal	4	no	17.274	17.211	EPSD	CCLE	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q16254	E2F4	P27361	MAPK3	S21	H18L	18	Missense	distal	-3	no	9.905	9.861	EPSD	CCLE	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q8NET8	TRPV3	P27361	MAPK3	T35	P31T	31	Missense	distal	-4	no	13.858	13.827	EPSD	CCLE	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P41182	BCL6	P27361	MAPK3	S3	A2T	2	Missense	proximal	-1	no	12.756	12.860	EPSD	CCLE	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P41182	BCL6	P27361	MAPK3	S250	C254S	254	Missense	distal	4	no	16.503	17.006	EPSD	CCLE	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P41182	BCL6	P27361	MAPK3	S260	C254S	254	Missense	distal	-6	no	15.759	16.319	EPSD	CCLE	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P41182	BCL6	P27361	MAPK3	S457	E463K	463	Missense	distal	6	no	16.788	16.712	EPSD	CCLE	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P41182	BCL6	P27361	MAPK3	S460	E463K	463	Missense	distal	3	no	9.365	9.355	EPSD	CCLE	9.358	Loss
CMGC_MAPK_ERK1_MAPK3_ST	P41182	BCL6	P27361	MAPK3	S466	E463K	463	Missense	distal	-3	no	16.090	16.059	EPSD	CCLE	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q13164	MAPK7	P27361	MAPK3	T280	V285M	285	Missense	distal	5	no	15.650	15.525	EPSD	CCLE	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q13164	MAPK7	P27361	MAPK3	S282	V285M	285	Missense	distal	3	no	16.909	16.884	EPSD	CCLE	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q13164	MAPK7	P27361	MAPK3	T553	D554Y	554	Missense	proximal	1	no	9.750	11.303	EPSD	CCLE	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q13164	MAPK7	P27361	MAPK3	T594	P587L	587	Missense	distal	-7	no	13.741	13.848	EPSD	CCLE	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q01844	EWSR1	P27361	MAPK3	T79	T75I	75	Missense	distal	-4	no	13.962	13.861	PhosphoSitePlus	CCLE	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q9H9Z2	LIN28A	P27361	MAPK3	S200	T202A	202	Missense	proximal	2	no	18.673	18.646	PhosphoSitePlus	CCLE	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q9H9Z2	LIN28A	P27361	MAPK3	T202	T202A	202	Missense	central	0	yes	10.015	0.000	EPSD	CCLE	9.358	Loss
CMGC_MAPK_ERK1_MAPK3_ST	Q12772	SREBF2	P27361	MAPK3	S79	S73G	73	Missense	distal	-6	no	9.393	9.331	EPSD	CCLE	9.358	Loss
CMGC_MAPK_ERK1_MAPK3_ST	Q12772	SREBF2	P27361	MAPK3	S79	S81N	81	Missense	proximal	2	no	9.393	9.376	EPSD	CCLE	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q12772	SREBF2	P27361	MAPK3	S432	S436A	436	Missense	distal	4	no	16.998	16.667	EPSD;PhosphoSitePlus	CCLE	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q12772	SREBF2	P27361	MAPK3	S1046	R1049H	1049	Missense	distal	3	no	14.561	14.569	EPSD	CCLE	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P05787	KRT8	P27361	MAPK3	S436	G440D	440	Missense	distal	4	no	10.523	10.564	EPSD	CCLE	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P05787	KRT8	P27361	MAPK3	S450	S451F	451	Missense	proximal	1	no	7.614	10.454	EPSD	CCLE	9.358	Gain
CMGC_MAPK_ERK1_MAPK3_ST	P05787	KRT8	P27361	MAPK3	S451	S451F	451	Missense	central	0	yes	12.153	0.000	EPSD	CCLE	9.358	Loss
CMGC_MAPK_ERK1_MAPK3_ST	P05787	KRT8	P27361	MAPK3	S457	S451F	451	Missense	distal	-6	no	9.641	9.174	EPSD	CCLE	9.358	Loss
CMGC_MAPK_ERK1_MAPK3_ST	P06401	PGR	P27361	MAPK3	S25	C29Y	29	Missense	distal	4	no	19.870	20.158	EPSD	CCLE	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P06401	PGR	P27361	MAPK3	S328	L323P	323	Missense	distal	-5	no	10.883	10.938	EPSD	CCLE	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P06401	PGR	P27361	MAPK3	S345	A348G	348	Missense	distal	3	no	15.926	15.955	EPSD	CCLE	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P06401	PGR	P27361	MAPK3	T351	A348G	348	Missense	distal	-3	no	17.189	17.248	EPSD	CCLE	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P06401	PGR	P27361	MAPK3	S676	I681V	681	Missense	distal	5	no	17.015	17.141	EPSD	CCLE	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q15596	NCOA2	P27361	MAPK3	S29	D24E	24	Missense	distal	-5	no	17.592	17.593	EPSD	CCLE	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q15596	NCOA2	P27361	MAPK3	S554	S550L	550	Missense	distal	-4	no	15.398	15.258	EPSD	CCLE	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q15596	NCOA2	P27361	MAPK3	S655	P654S	654	Missense	proximal	-1	no	14.809	14.803	EPSD	CCLE	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q15596	NCOA2	P27361	MAPK3	S736	E733V	733	Missense	distal	-3	no	18.552	18.499	PhosphoSitePlus	CCLE	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P17676	CEBPB	P27361	MAPK3	S231	P236L	236	Missense	distal	5	no	17.553	17.326	EPSD	CCLE	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P17676	CEBPB	P27361	MAPK3	S231	P238L	238	Missense	distal	7	no	17.553	17.746	EPSD	CCLE	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P17676	CEBPB	P27361	MAPK3	T235	P236L	236	Missense	proximal	1	no	16.764	7.726	PhosphoSitePlus	CCLE	9.358	Loss
CMGC_MAPK_ERK1_MAPK3_ST	P17676	CEBPB	P27361	MAPK3	T235	P238L	238	Missense	distal	3	no	16.764	16.727	PhosphoSitePlus	CCLE	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P17676	CEBPB	P27361	MAPK3	S237	P236L	236	Missense	proximal	-1	no	16.964	16.869	EPSD	CCLE	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P17676	CEBPB	P27361	MAPK3	S237	P238L	238	Missense	proximal	1	no	16.964	7.926	EPSD	CCLE	9.358	Loss
CMGC_MAPK_ERK1_MAPK3_ST	P36956	SREBF1	P27361	MAPK3	S63	P69T	69	Missense	distal	6	no	19.717	19.692	EPSD	CCLE	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P36956	SREBF1	P27361	MAPK3	S63	A62V	62	Missense	proximal	-1	no	19.717	19.767	EPSD	CCLE	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P36956	SREBF1	P27361	MAPK3	T105	K108Q	108	Missense	distal	3	no	13.759	13.760	EPSD	CCLE	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P36956	SREBF1	P27361	MAPK3	T426	E422D	422	Missense	distal	-4	no	13.292	13.281	EPSD	CCLE	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P36956	SREBF1	P27361	MAPK3	S524	S520G	520	Missense	distal	-4	no	17.382	17.343	EPSD	CCLE	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	O60504	SORBS3	P27361	MAPK3	S373	P374Q	374	Missense	proximal	1	no	14.892	6.948	EPSD	CCLE	9.358	Loss
CMGC_MAPK_ERK1_MAPK3_ST	O60504	SORBS3	P27361	MAPK3	S563	G560E	560	Missense	distal	-3	no	14.694	14.707	EPSD	CCLE	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P04150	NR3C1	P27361	MAPK3	S395	S394L	394	Missense	proximal	-1	no	16.269	16.180	EPSD	CCLE	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P04150	NR3C1	P27361	MAPK3	S395	G392D	392	Missense	distal	-3	no	16.269	16.279	EPSD	CCLE	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P43364	MAGEA11	P27361	MAPK3	S76	T80N	80	Missense	distal	4	no	15.314	15.280	EPSD	CCLE	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P43364	MAGEA11	P27361	MAPK3	S168	E162Q	162	Missense	distal	-6	no	17.154	17.020	EPSD	CCLE	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P43364	MAGEA11	P27361	MAPK3	S168	E167V	167	Missense	proximal	-1	no	17.154	17.095	EPSD	CCLE	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P43364	MAGEA11	P27361	MAPK3	S170	E167V	167	Missense	distal	-3	no	16.417	16.364	EPSD	CCLE	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P43364	MAGEA11	P27361	MAPK3	S174	E167V	167	Missense	distal	-7	no	17.385	17.501	PhosphoSitePlus	CCLE	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P10242	MYB	P27361	MAPK3	T433	H436Y	436	Missense	distal	3	no	13.926	13.910	EPSD	CCLE	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P10242	MYB	P27361	MAPK3	T452	R457G	457	Missense	distal	5	no	14.557	14.636	EPSD	CCLE	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P10242	MYB	P27361	MAPK3	S463	R457G	457	Missense	distal	-6	no	15.643	15.741	EPSD	CCLE	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P10242	MYB	P27361	MAPK3	S560	Q554K	554	Missense	distal	-6	no	15.465	15.457	EPSD	CCLE	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P35568	IRS1	P27361	MAPK3	S295	R302Q	302	Missense	distal	7	no	10.617	10.647	EPSD	CCLE	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P35568	IRS1	P27361	MAPK3	S312	A314D	314	Missense	proximal	2	no	14.927	14.954	EPSD	CCLE	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P35568	IRS1	P27361	MAPK3	S402	T403P	403	Missense	proximal	1	no	6.410	15.287	EPSD	CCLE	9.358	Gain
CMGC_MAPK_ERK1_MAPK3_ST	P35568	IRS1	P27361	MAPK3	S531	P532S	532	Missense	proximal	1	no	14.834	5.781	EPSD	CCLE	9.358	Loss
CMGC_MAPK_ERK1_MAPK3_ST	P35568	IRS1	P27361	MAPK3	S672	P679R	679	Missense	distal	7	no	15.175	15.267	EPSD	CCLE	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P35568	IRS1	P27361	MAPK3	S736	V738M	738	Missense	proximal	2	no	15.159	15.141	EPSD	CCLE	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P35568	IRS1	P27361	MAPK3	S745	S747A	747	Missense	proximal	2	no	15.265	15.227	EPSD	CCLE	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P35568	IRS1	P27361	MAPK3	S745	V738M	738	Missense	distal	-7	no	15.265	15.321	EPSD	CCLE	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P35568	IRS1	P27361	MAPK3	T1107	S1105F	1105	Missense	proximal	-2	no	14.450	13.150	EPSD	CCLE	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P35568	IRS1	P27361	MAPK3	S1145	R1152I	1152	Missense	distal	7	no	11.323	11.552	EPSD	CCLE	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	P46527	CDKN1B	P27361	MAPK3	S10	S12I	12	Missense	proximal	2	no	14.456	14.421	EPSD	CCLE	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q14934	NFATC4	P27361	MAPK3	S168	S174N	174	Missense	distal	6	no	15.668	15.439	EPSD	CCLE	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q14934	NFATC4	P27361	MAPK3	S170	S174N	174	Missense	distal	4	no	17.114	16.967	EPSD	CCLE	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q14934	NFATC4	P27361	MAPK3	S217	S221F	221	Missense	distal	4	no	17.123	16.708	EPSD	CCLE	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q14934	NFATC4	P27361	MAPK3	S221	S221F	221	Missense	central	0	yes	14.393	0.000	EPSD	CCLE	9.358	Loss
CMGC_MAPK_ERK1_MAPK3_ST	Q14934	NFATC4	P27361	MAPK3	T226	S221F	221	Missense	distal	-5	no	16.191	16.057	EPSD	CCLE	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q14934	NFATC4	P27361	MAPK3	S592	A590T	590	Missense	proximal	-2	no	14.486	15.851	EPSD	CCLE	9.358	Up-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q14934	NFATC4	P27361	MAPK3	S716	P720L	720	Missense	distal	4	no	17.356	17.202	EPSD	CCLE	9.358	Down-regulation
CMGC_MAPK_ERK1_MAPK3_ST	Q14934	NFATC4	P27361	MAPK3	S819	P820L	820	Missense	proximal	1	no	18.092	9.054	EPSD	CCLE	9.358	Loss
CMGC_MAPK_ERK1_MAPK3_ST	Q9UPT5	EXOC7	P27361	MAPK3	S250	A252D	252	Missense	proximal	2	no	18.233	18.260	PhosphoSitePlus	CCLE	9.358	Up-regulation
TKL_RIPK_RIPK3_ST	Q9UER7	DAXX	Q9Y572	RIPK3	S33	P29L	29	Missense	distal	-4	no	27.419	27.351	EPSD	CCLE	23.118	Down-regulation
TKL_RIPK_RIPK3_ST	Q9UER7	DAXX	Q9Y572	RIPK3	S33	P29S	29	Missense	distal	-4	no	27.419	27.103	EPSD	CCLE	23.118	Down-regulation
TKL_RIPK_RIPK3_ST	Q9UER7	DAXX	Q9Y572	RIPK3	S110	A103V	103	Missense	distal	-7	no	27.214	27.062	EPSD	CCLE	23.118	Down-regulation
TKL_RIPK_RIPK3_ST	Q9UER7	DAXX	Q9Y572	RIPK3	T584	T578I	578	Missense	distal	-6	no	24.391	24.152	EPSD	CCLE	23.118	Down-regulation
TKL_RIPK_RIPK3_ST	Q9UER7	DAXX	Q9Y572	RIPK3	S690	S696N	696	Missense	distal	6	no	26.081	24.649	EPSD	CCLE	23.118	Down-regulation
TKL_RIPK_RIPK3_ST	Q9UER7	DAXX	Q9Y572	RIPK3	S690	S683Y	683	Missense	distal	-7	no	26.081	24.820	EPSD	CCLE	23.118	Down-regulation
TKL_RIPK_RIPK3_ST	Q9UER7	DAXX	Q9Y572	RIPK3	T695	P701S	701	Missense	distal	6	no	23.693	26.898	EPSD	CCLE	23.118	Up-regulation
TKL_RIPK_RIPK3_ST	Q9UER7	DAXX	Q9Y572	RIPK3	T695	S696N	696	Missense	proximal	1	no	23.693	24.860	EPSD	CCLE	23.118	Up-regulation
TKL_RIPK_RIPK3_ST	P09622	DLD	Q9Y572	RIPK3	S208	K211N	211	Missense	distal	3	no	24.972	24.717	EPSD	CCLE	23.118	Down-regulation
TKL_RIPK_RIPK3_ST	P09622	DLD	Q9Y572	RIPK3	T276	T282M	282	Missense	distal	6	no	25.073	23.946	EPSD	CCLE	23.118	Down-regulation
STE_STE20_KHS_MAP4K1_ST	Q9BXL7	CARD11	Q92918	MAP4K1	T532	A534N	534	Missense	proximal	2	no	2.288	1.710	EPSD	CCLE	2.024	Loss
STE_STE20_KHS_MAP4K1_ST	Q9BXL7	CARD11	Q92918	MAP4K1	S535	A534N	534	Missense	proximal	-1	no	3.463	3.088	EPSD	CCLE	2.024	Down-regulation
STE_STE20_KHS_MAP4K1_ST	Q9BXL7	CARD11	Q92918	MAP4K1	S556	S558T	558	Missense	proximal	2	no	7.521	7.222	PhosphoSitePlus;EPSD	CCLE	2.024	Down-regulation
STE_STE20_KHS_MAP4K1_ST	Q9BXL7	CARD11	Q92918	MAP4K1	T564	E566G	566	Missense	proximal	2	no	3.729	3.537	EPSD	CCLE	2.024	Down-regulation
STE_STE20_KHS_MAP4K1_ST	Q9BXL7	CARD11	Q92918	MAP4K1	T564	S558T	558	Missense	distal	-6	no	3.729	3.553	EPSD	CCLE	2.024	Down-regulation
STE_STE20_KHS_MAP4K1_ST	Q92918	MAP4K1	Q92918	MAP4K1	S430	V424A	424	Missense	distal	-6	no	2.575	2.986	EPSD	CCLE	2.024	Up-regulation
STE_STE20_KHS_MAP4K1_ST	Q92918	MAP4K1	Q92918	MAP4K1	S430	G423E	423	Missense	distal	-7	no	2.575	2.649	EPSD	CCLE	2.024	Up-regulation
STE_STE20_KHS_MAP4K1_ST	Q13094	LCP2	Q92918	MAP4K1	S207	P201L	201	Missense	distal	-6	no	2.004	2.099	EPSD	CCLE	2.024	Gain
Other_CAMKK_CAMKK-Meta_CAMKK1_ST	Q16566	CAMK4	Q8N5S9	CAMKK1	S12	S12L	12	Missense	central	0	yes	2.421	0.000	EPSD;PhosphoSitePlus	CCLE	1.176	Loss
Other_CAMKK_CAMKK-Meta_CAMKK1_ST	Q16566	CAMK4	Q8N5S9	CAMKK1	S13	S12L	12	Missense	proximal	-1	no	2.064	2.043	EPSD;PhosphoSitePlus	CCLE	1.176	Down-regulation
Other_CAMKK_CAMKK-Meta_CAMKK1_ST	Q8TDC3	BRSK1	Q8N5S9	CAMKK1	S499	P501S	501	Missense	proximal	2	no	1.631	1.684	EPSD	CCLE	1.176	Up-regulation
Other_CAMKK_CAMKK-Meta_CAMKK1_ST	Q13131	PRKAA1	Q8N5S9	CAMKK1	T490	S494L	494	Missense	distal	4	no	1.195	1.066	EPSD	CCLE	1.176	Loss
Other_CAMKK_CAMKK-Meta_CAMKK1_ST	Q13131	PRKAA1	Q8N5S9	CAMKK1	T490	S494W	494	Missense	distal	4	no	1.195	1.020	EPSD	CCLE	1.176	Loss
Other_CAMKK_CAMKK-Meta_CAMKK1_ST	Q13131	PRKAA1	Q8N5S9	CAMKK1	S498	S494L	494	Missense	distal	-4	no	1.198	1.091	EPSD	CCLE	1.176	Loss
Other_CAMKK_CAMKK-Meta_CAMKK1_ST	Q13131	PRKAA1	Q8N5S9	CAMKK1	S498	S494W	494	Missense	distal	-4	no	1.198	1.105	EPSD	CCLE	1.176	Loss
Other_CAMKK_CAMKK-Meta_CAMKK1_ST	Q13131	PRKAA1	Q8N5S9	CAMKK1	T522	L521V	521	Missense	proximal	-1	no	1.486	1.482	EPSD	CCLE	1.176	Down-regulation
Other_CAMKK_CAMKK-Meta_CAMKK1_ST	Q13131	PRKAA1	Q8N5S9	CAMKK1	S524	L521V	521	Missense	distal	-3	no	1.448	1.453	EPSD	CCLE	1.176	Up-regulation
Other_CAMKK_CAMKK-Meta_CAMKK1_ST	Q13131	PRKAA1	Q8N5S9	CAMKK1	S527	L521V	521	Missense	distal	-6	no	2.750	2.776	EPSD	CCLE	1.176	Up-regulation
Other_CAMKK_CAMKK-Meta_CAMKK1_ST	Q8IU85	CAMK1D	Q8N5S9	CAMKK1	S327	L324I	324	Missense	distal	-3	no	1.519	1.603	EPSD	CCLE	1.176	Up-regulation
Other_CAMKK_CAMKK-Meta_CAMKK1_ST	Q8IU85	CAMK1D	Q8N5S9	CAMKK1	S327	A333T	333	Missense	distal	6	no	1.519	1.525	EPSD	CCLE	1.176	Up-regulation
CK1_CK1_CK1-D_CSNK1D_ST	O15055	PER2	P48730	CSNK1D	S810	G815W	815	Missense	distal	5	no	13.908	12.536	EPSD	CCLE	11.915	Down-regulation
CK1_CK1_CK1-D_CSNK1D_ST	P10636	MAPT	P48730	CSNK1D	S64	A66V	66	Missense	proximal	2	no	15.022	13.863	EPSD	CCLE	11.915	Down-regulation
CK1_CK1_CK1-D_CSNK1D_ST	P10636	MAPT	P48730	CSNK1D	S68	A66V	66	Missense	proximal	-2	no	14.093	11.392	EPSD	CCLE	11.915	Loss
CK1_CK1_CK1-D_CSNK1D_ST	P10636	MAPT	P48730	CSNK1D	T71	A66V	66	Missense	distal	-5	no	12.010	12.504	EPSD	CCLE	11.915	Up-regulation
CK1_CK1_CK1-D_CSNK1D_ST	P10636	MAPT	P48730	CSNK1D	S113	G107V	107	Missense	distal	-6	no	16.388	16.882	EPSD	CCLE	11.915	Up-regulation
CK1_CK1_CK1-D_CSNK1D_ST	P10636	MAPT	P48730	CSNK1D	T167	P170F	170	Missense	distal	3	no	10.768	12.377	EPSD	CCLE	11.915	Gain
CK1_CK1_CK1-D_CSNK1D_ST	P10636	MAPT	P48730	CSNK1D	S171	P170F	170	Missense	proximal	-1	no	13.725	14.416	EPSD	CCLE	11.915	Up-regulation
CK1_CK1_CK1-D_CSNK1D_ST	P10636	MAPT	P48730	CSNK1D	S171	G174A	174	Missense	distal	3	no	13.725	14.325	EPSD	CCLE	11.915	Up-regulation
CK1_CK1_CK1-D_CSNK1D_ST	P10636	MAPT	P48730	CSNK1D	S228	D221Y	221	Missense	distal	-7	no	15.102	12.797	EPSD	CCLE	11.915	Down-regulation
CK1_CK1_CK1-D_CSNK1D_ST	P10636	MAPT	P48730	CSNK1D	S228	P234S	234	Missense	distal	6	no	15.102	17.393	EPSD	CCLE	11.915	Up-regulation
CK1_CK1_CK1-D_CSNK1D_ST	P10636	MAPT	P48730	CSNK1D	S238	P234S	234	Missense	distal	-4	no	14.130	14.595	EPSD	CCLE	11.915	Up-regulation
CK1_CK1_CK1-D_CSNK1D_ST	P10636	MAPT	P48730	CSNK1D	S238	D242H	242	Missense	distal	4	no	14.130	14.499	EPSD	CCLE	11.915	Up-regulation
CK1_CK1_CK1-D_CSNK1D_ST	P10636	MAPT	P48730	CSNK1D	S512	G518S	518	Missense	distal	6	no	11.717	13.188	EPSD	CCLE	11.915	Gain
CK1_CK1_CK1-D_CSNK1D_ST	P10636	MAPT	P48730	CSNK1D	S515	G518S	518	Missense	distal	3	no	11.805	12.727	EPSD	CCLE	11.915	Gain
CK1_CK1_CK1-D_CSNK1D_ST	P10636	MAPT	P48730	CSNK1D	T522	G518S	518	Missense	distal	-4	no	14.745	15.036	EPSD	CCLE	11.915	Up-regulation
CK1_CK1_CK1-D_CSNK1D_ST	P10636	MAPT	P48730	CSNK1D	T522	R526L	526	Missense	distal	4	no	14.745	14.863	EPSD	CCLE	11.915	Up-regulation
CK1_CK1_CK1-D_CSNK1D_ST	P10636	MAPT	P48730	CSNK1D	S525	G518S	518	Missense	distal	-7	no	12.146	11.491	EPSD	CCLE	11.915	Loss
CK1_CK1_CK1-D_CSNK1D_ST	P10636	MAPT	P48730	CSNK1D	S525	R526L	526	Missense	proximal	1	no	12.146	13.077	EPSD	CCLE	11.915	Up-regulation
CK1_CK1_CK1-D_CSNK1D_ST	P10636	MAPT	P48730	CSNK1D	S713	G706V	706	Missense	distal	-7	no	13.580	11.324	EPSD	CCLE	11.915	Loss
CK1_CK1_CK1-D_CSNK1D_ST	P10636	MAPT	P48730	CSNK1D	S713	S717C	717	Missense	distal	4	no	13.580	13.599	EPSD	CCLE	11.915	Up-regulation
CK1_CK1_CK1-D_CSNK1D_ST	P10636	MAPT	P48730	CSNK1D	S721	S717C	717	Missense	distal	-4	no	18.393	18.302	EPSD	CCLE	11.915	Down-regulation
CK1_CK1_CK1-D_CSNK1D_ST	P10636	MAPT	P48730	CSNK1D	S721	S721C	721	Missense	central	0	yes	18.393	0.000	EPSD	CCLE	11.915	Loss
CK1_CK1_CK1-D_CSNK1D_ST	P10636	MAPT	P48730	CSNK1D	S721	H724R	724	Missense	distal	3	no	18.393	16.312	EPSD	CCLE	11.915	Down-regulation
CK1_CK1_CK1-D_CSNK1D_ST	Q99814	EPAS1	P48730	CSNK1D	S383	L389I	389	Missense	distal	6	no	16.536	15.506	EPSD;PhosphoSitePlus	CCLE	11.915	Down-regulation
CK1_CK1_CK1-D_CSNK1D_ST	Q13148	TARDBP	P48730	CSNK1D	T88	V94L	94	Missense	distal	6	no	13.047	14.100	EPSD	CCLE	11.915	Up-regulation
CK1_CK1_CK1-D_CSNK1D_ST	Q13148	TARDBP	P48730	CSNK1D	S92	V94L	94	Missense	proximal	2	no	14.725	13.633	EPSD;PhosphoSitePlus	CCLE	11.915	Down-regulation
CK1_CK1_CK1-D_CSNK1D_ST	Q13148	TARDBP	P48730	CSNK1D	S92	A99V	99	Missense	distal	7	no	14.725	15.647	EPSD;PhosphoSitePlus	CCLE	11.915	Up-regulation
CK1_CK1_CK1-D_CSNK1D_ST	Q13148	TARDBP	P48730	CSNK1D	S389	N390S	390	Missense	proximal	1	no	12.633	11.313	EPSD;PhosphoSitePlus	CCLE	11.915	Loss
CK1_CK1_CK1-D_CSNK1D_ST	Q13148	TARDBP	P48730	CSNK1D	S393	N390S	390	Missense	distal	-3	no	18.774	20.983	PhosphoSitePlus;EPSD	CCLE	11.915	Up-regulation
CK1_CK1_CK1-D_CSNK1D_ST	Q13148	TARDBP	P48730	CSNK1D	S395	N390S	390	Missense	distal	-5	no	17.157	15.460	EPSD;PhosphoSitePlus	CCLE	11.915	Down-regulation
CK1_CK1_CK1-D_CSNK1D_ST	O14641	DVL2	P48730	CSNK1D	S126	P119S	119	Missense	distal	-7	no	12.649	12.164	EPSD	CCLE	11.915	Down-regulation
CK1_CK1_CK1-D_CSNK1D_ST	O14641	DVL2	P48730	CSNK1D	S169	E171K	171	Missense	proximal	2	no	12.854	12.092	EPSD	CCLE	11.915	Down-regulation
CK1_CK1_CK1-D_CSNK1D_ST	O14641	DVL2	P48730	CSNK1D	S616	E613A	613	Missense	distal	-3	no	16.189	14.302	EPSD	CCLE	11.915	Down-regulation
CK1_CK1_CK1-D_CSNK1D_ST	O14641	DVL2	P48730	CSNK1D	S620	E613A	613	Missense	distal	-7	no	12.404	11.902	EPSD	CCLE	11.915	Loss
CK1_CK1_CK1-D_CSNK1D_ST	P25054	APC	P48730	CSNK1D	S5	A2V	2	Missense	distal	-3	no	12.628	11.822	EPSD	CCLE	11.915	Loss
CK1_CK1_CK1-D_CSNK1D_ST	P25054	APC	P48730	CSNK1D	T1556	D1558E	1558	Missense	proximal	2	no	12.380	12.526	EPSD	CCLE	11.915	Up-regulation
CK1_CK1_CK1-D_CSNK1D_ST	P25054	APC	P48730	CSNK1D	S2034	D2033E	2033	Missense	proximal	-1	no	12.704	13.220	EPSD	CCLE	11.915	Up-regulation
CK1_CK1_CK1-D_CSNK1D_ST	P25054	APC	P48730	CSNK1D	S2207	G2211C	2211	Missense	distal	4	no	13.333	13.228	EPSD	CCLE	11.915	Down-regulation
CK1_CK1_CK1-D_CSNK1D_ST	P25054	APC	P48730	CSNK1D	S2359	S2361F	2361	Missense	proximal	2	no	14.602	13.928	EPSD	CCLE	11.915	Down-regulation
CK1_CK1_CK1-D_CSNK1D_ST	P25054	APC	P48730	CSNK1D	T2629	T2635P	2635	Missense	distal	6	no	12.809	13.419	EPSD	CCLE	11.915	Up-regulation
CK1_CK1_CK1-D_CSNK1D_ST	P25054	APC	P48730	CSNK1D	S2631	T2635P	2635	Missense	distal	4	no	11.893	11.920	EPSD	CCLE	11.915	Gain
CK1_CK1_CK1-D_CSNK1D_ST	P25054	APC	P48730	CSNK1D	T2635	T2635P	2635	Missense	central	0	yes	12.118	0.000	EPSD	CCLE	11.915	Loss
CK1_CK1_CK1-D_CSNK1D_ST	Q14511	NEDD9	P48730	CSNK1D	S395	A397T	397	Missense	proximal	2	no	14.119	12.613	EPSD	CCLE	11.915	Down-regulation
CK1_CK1_CK1-D_CSNK1D_ST	P46937	YAP1	P48730	CSNK1D	S274	I273T	273	Missense	proximal	-1	no	12.283	10.660	EPSD	CCLE	11.915	Loss
CK1_CK1_CK1-D_CSNK1D_ST	O43312	MTSS1	P48730	CSNK1D	S446	A445T	445	Missense	proximal	-1	no	14.585	13.231	EPSD	CCLE	11.915	Down-regulation
CK1_CK1_CK1-D_CSNK1D_ST	Q9BZL6	PRKD2	P48730	CSNK1D	S200	A202T	202	Missense	proximal	2	no	14.712	13.206	EPSD	CCLE	11.915	Down-regulation
CK1_CK1_CK1-D_CSNK1D_ST	P30291	WEE1	P48730	CSNK1D	S67	P64S	64	Missense	distal	-3	no	8.855	12.855	EPSD	CCLE	11.915	Gain
CK1_CK1_CK1-D_CSNK1D_ST	Q16665	HIF1A	P48730	CSNK1D	S14	K10E	10	Missense	distal	-4	no	12.497	12.646	EPSD	CCLE	11.915	Up-regulation
CK1_CK1_CK1-D_CSNK1D_ST	Q16665	HIF1A	P48730	CSNK1D	S14	I13M	13	Missense	proximal	-1	no	12.497	10.565	EPSD	CCLE	11.915	Loss
CK1_CK1_CK1-D_CSNK1D_ST	Q16665	HIF1A	P48730	CSNK1D	S31	S34Y	34	Missense	distal	3	no	13.466	9.637	EPSD	CCLE	11.915	Loss
CK1_CK1_CK1-D_CSNK1D_ST	Q16665	HIF1A	P48730	CSNK1D	T301	L308I	308	Missense	distal	7	no	12.958	11.380	EPSD	CCLE	11.915	Loss
Atypical_PDHK_PDHK_PDK4_ST	P29803	PDHA2	Q16654	PDK4	T231	G228E	228	Missense	distal	-3	no	1.976	2.139	EPSD	CCLE	1.272	Up-regulation
Atypical_PDHK_PDHK_PDK4_ST	P29803	PDHA2	Q16654	PDK4	T284	H288Y	288	Missense	distal	4	no	2.392	2.354	EPSD	CCLE	1.272	Down-regulation
Atypical_PDHK_PDHK_PDK4_ST	P29803	PDHA2	Q16654	PDK4	T284	H288R	288	Missense	distal	4	no	2.392	2.742	EPSD	CCLE	1.272	Up-regulation
Atypical_PDHK_PDHK_PDK4_ST	P29803	PDHA2	Q16654	PDK4	S291	H288Y	288	Missense	distal	-3	no	13.830	13.763	EPSD;PhosphoSitePlus	CCLE	1.272	Down-regulation
Atypical_PDHK_PDHK_PDK4_ST	P29803	PDHA2	Q16654	PDK4	S291	H288R	288	Missense	distal	-3	no	13.830	13.742	EPSD;PhosphoSitePlus	CCLE	1.272	Down-regulation
Other_PLK_SAK_PLK4_ST	O00444	PLK4	O00444	PLK4	S298	T292A	292	Missense	distal	-6	no	437.770	445.045	EPSD	CCLE	416.076	Up-regulation
Other_PLK_SAK_PLK4_ST	O00444	PLK4	O00444	PLK4	S305	F307L	307	Missense	proximal	2	no	601.221	645.636	EPSD;PhosphoSitePlus	CCLE	416.076	Up-regulation
Other_PLK_SAK_PLK4_ST	Q15154	PCM1	O00444	PLK4	S588	I592L	592	Missense	distal	4	no	513.967	543.445	EPSD	CCLE	416.076	Up-regulation
Other_PLK_SAK_PLK4_ST	Q15154	PCM1	O00444	PLK4	S639	L645V	645	Missense	distal	6	no	450.315	392.630	EPSD	CCLE	416.076	Loss
Other_PLK_SAK_PLK4_ST	Q15154	PCM1	O00444	PLK4	S690	Q686P	686	Missense	distal	-4	no	425.538	425.360	EPSD	CCLE	416.076	Down-regulation
Other_PLK_SAK_PLK4_ST	Q15154	PCM1	O00444	PLK4	S690	I689T	689	Missense	proximal	-1	no	425.538	437.813	EPSD	CCLE	416.076	Up-regulation
Other_PLK_SAK_PLK4_ST	Q15154	PCM1	O00444	PLK4	S690	N695Y	695	Missense	distal	5	no	425.538	429.623	EPSD	CCLE	416.076	Up-regulation
Other_PLK_SAK_PLK4_ST	Q15154	PCM1	O00444	PLK4	S694	I689T	689	Missense	distal	-5	no	449.069	448.621	EPSD	CCLE	416.076	Down-regulation
Other_PLK_SAK_PLK4_ST	Q15154	PCM1	O00444	PLK4	S694	N695Y	695	Missense	proximal	1	no	449.069	441.193	EPSD	CCLE	416.076	Down-regulation
Other_PLK_SAK_PLK4_ST	O43303	CCP110	O00444	PLK4	T382	A385E	385	Missense	distal	3	no	478.780	438.766	EPSD	CCLE	416.076	Down-regulation
Other_Aur_AURKC_ST	Q9NQS7	INCENP	Q9UQB9	AURKC	S91	R88C	88	Missense	distal	-3	no	19.994	18.632	EPSD	CCLE	14.093	Down-regulation
Other_Aur_AURKC_ST	Q9NQS7	INCENP	Q9UQB9	AURKC	S94	R88C	88	Missense	distal	-6	no	18.704	18.926	EPSD	CCLE	14.093	Up-regulation
Other_Aur_AURKC_ST	Q9NQS7	INCENP	Q9UQB9	AURKC	T184	A179V	179	Missense	distal	-5	no	19.442	19.282	EPSD	CCLE	14.093	Down-regulation
Other_Aur_AURKC_ST	Q9NQS7	INCENP	Q9UQB9	AURKC	S336	K341R	341	Missense	distal	5	no	18.620	18.680	EPSD	CCLE	14.093	Up-regulation
Other_Aur_AURKC_ST	Q9NQS7	INCENP	Q9UQB9	AURKC	S486	S486R	486	Missense	central	0	yes	15.849	0.000	EPSD	CCLE	14.093	Loss
Other_Aur_AURKC_ST	Q9NQS7	INCENP	Q9UQB9	AURKC	T892	R887C	887	Missense	distal	-5	no	30.253	29.982	EPSD;PhosphoSitePlus	CCLE	14.093	Down-regulation
Other_Aur_AURKC_ST	Q9NQS7	INCENP	Q9UQB9	AURKC	S893	R887C	887	Missense	distal	-6	no	32.340	32.563	EPSD;PhosphoSitePlus	CCLE	14.093	Up-regulation
Other_Aur_AURKC_ST	Q9NQS7	INCENP	Q9UQB9	AURKC	S894	R887C	887	Missense	distal	-7	no	30.434	30.919	PhosphoSitePlus;EPSD	CCLE	14.093	Up-regulation
Other_Aur_AURKC_ST	O15392	BIRC5	Q9UQB9	AURKC	S82	G83R	83	Missense	proximal	1	no	14.197	15.814	EPSD	CCLE	14.093	Up-regulation
Other_Aur_AURKC_ST	O75410	TACC1	Q9UQB9	AURKC	T302	S300N	300	Missense	proximal	-2	no	14.145	12.201	EPSD	CCLE	14.093	Loss
Other_Aur_AURKC_ST	O75410	TACC1	Q9UQB9	AURKC	S361	Q354E	354	Missense	distal	-7	no	14.188	14.399	EPSD	CCLE	14.093	Up-regulation
STE_STE7_MEK7_MAP2K7_ST	P45984	MAPK9	O14733	MAP2K7	S390	N384K	384	Missense	distal	-6	no	2.742	2.774	EPSD	CCLE	2.107	Up-regulation
STE_STE7_MEK7_MAP2K7_ST	P45984	MAPK9	O14733	MAP2K7	S407	D414Y	414	Missense	distal	7	no	5.531	5.546	PhosphoSitePlus;EPSD	CCLE	2.107	Up-regulation
STE_STE7_MEK7_MAP2K7_ST	P45983	MAPK8	O14733	MAP2K7	T183	T188N	188	Missense	distal	5	no	9.246	8.555	PhosphoSitePlus;EPSD	CCLE	2.107	Down-regulation
STE_STE7_MEK7_MAP2K7_ST	P45983	MAPK8	O14733	MAP2K7	T183	T188I	188	Missense	distal	5	no	9.246	7.714	PhosphoSitePlus;EPSD	CCLE	2.107	Down-regulation
STE_STE7_MEK7_MAP2K7_ST	Q13158	FADD	O14733	MAP2K7	S194	M193T	193	Missense	proximal	-1	no	5.970	4.518	PhosphoSitePlus	CCLE	2.107	Down-regulation
STE_STE7_MEK7_MAP2K7_ST	Q13158	FADD	O14733	MAP2K7	S197	M193T	193	Missense	distal	-4	no	2.596	3.080	EPSD	CCLE	2.107	Up-regulation
TK_Src_Frk_FRK_Y	P38398	BRCA1	P42685	FRK	Y1552	D1557N	1557	Missense	distal	5	no	8.438	8.415	PhosphoSitePlus	CCLE	2.774	Down-regulation
TK_Src_Frk_FRK_Y	P38398	BRCA1	P42685	FRK	Y1563	D1557N	1557	Missense	distal	-6	no	3.100	3.016	EPSD	CCLE	2.774	Down-regulation
Other_NAK_MPSK_STK16_ST	Q9Y295	DRG1	O75716	STK16	T220	D218N	218	Missense	proximal	-2	no	1.922	1.925	EPSD	CCLE	1.527	Up-regulation
TK_EGFR_ERBB2_Y	P06493	CDK1	P04626	ERBB2	Y15	K9N	9	Missense	distal	-6	no	4.825	4.767	PhosphoSitePlus	CCLE	2.878	Down-regulation
AGC_DMPK_GEK_CDC42BPA_ST	Q5VT25	CDC42BPA	Q5VT25	CDC42BPA	S1697	S1697N	1697	Missense	central	0	yes	2.168	0.000	EPSD	CCLE	2.124	Loss
AGC_DMPK_GEK_CDC42BPA_ST	P24844	MYL9	Q5VT25	CDC42BPA	T97	G91A	91	Missense	distal	-6	no	2.207	2.232	EPSD	CCLE	2.124	Up-regulation
STE_STE20_FRAY_OXSR1_ST	Q13621	SLC12A1	O95747	OXSR1	S120	N127K	127	Missense	distal	7	no	46.596	46.735	EPSD;PhosphoSitePlus	CCLE	17.710	Up-regulation
STE_STE20_FRAY_OXSR1_ST	Q13621	SLC12A1	O95747	OXSR1	S122	N127K	127	Missense	distal	5	no	19.343	19.265	EPSD	CCLE	17.710	Down-regulation
STE_STE20_FRAY_OXSR1_ST	Q13621	SLC12A1	O95747	OXSR1	T882	T882K	882	Missense	central	0	yes	26.055	0.000	EPSD	CCLE	17.710	Loss
STE_STE20_FRAY_OXSR1_ST	Q13621	SLC12A1	O95747	OXSR1	S885	T882K	882	Missense	distal	-3	no	18.307	12.451	EPSD	CCLE	17.710	Loss
TK_Src_SrcA_SRC_Y	Q14790	CASP8	P12931	SRC	Y226	R233P	233	Missense	distal	7	no	20.696	20.678	EPSD	CCLE	20.673	Down-regulation
TK_Src_SrcA_SRC_Y	Q14790	CASP8	P12931	SRC	Y334	S338P	338	Missense	distal	4	no	21.016	20.994	EPSD	CCLE	20.673	Down-regulation
TK_Src_SrcA_SRC_Y	P60484	PTEN	P12931	SRC	Y46	R47W	47	Missense	proximal	1	no	22.622	22.538	EPSD;PhosphoSitePlus	CCLE	20.673	Down-regulation
TK_Src_SrcA_SRC_Y	P60484	PTEN	P12931	SRC	Y46	V53D	53	Missense	distal	7	no	22.622	22.526	EPSD;PhosphoSitePlus	CCLE	20.673	Down-regulation
TK_Src_SrcA_SRC_Y	P60484	PTEN	P12931	SRC	Y240	F243V	243	Missense	distal	3	no	21.485	21.218	EPSD;PhosphoSitePlus	CCLE	20.673	Down-regulation
TK_Src_SrcA_SRC_Y	Q13813	SPTAN1	P12931	SRC	Y976	A974D	974	Missense	proximal	-2	no	20.548	21.816	EPSD	CCLE	20.673	Gain
TK_Src_SrcA_SRC_Y	Q13813	SPTAN1	P12931	SRC	Y1073	H1074Q	1074	Missense	proximal	1	no	23.247	24.313	PhosphoSitePlus;EPSD	CCLE	20.673	Up-regulation
TK_Src_SrcA_SRC_Y	Q13813	SPTAN1	P12931	SRC	Y1176	M1179I	1179	Missense	distal	3	no	22.468	22.774	EPSD;PhosphoSitePlus	CCLE	20.673	Up-regulation
TK_Src_SrcA_SRC_Y	Q13813	SPTAN1	P12931	SRC	Y1411	A1412T	1412	Missense	proximal	1	no	22.713	22.258	EPSD	CCLE	20.673	Down-regulation
TK_Src_SrcA_SRC_Y	Q13813	SPTAN1	P12931	SRC	Y2430	E2428K	2428	Missense	proximal	-2	no	21.817	20.458	EPSD	CCLE	20.673	Loss
TK_Src_SrcA_SRC_Y	P35916	FLT4	P12931	SRC	Y833	Y830H	830	Missense	distal	-3	no	21.340	21.153	EPSD;PhosphoSitePlus	CCLE	20.673	Down-regulation
TK_Src_SrcA_SRC_Y	P06396	GSN	P12931	SRC	Y651	P655L	655	Missense	distal	4	no	21.179	21.207	EPSD;PhosphoSitePlus	CCLE	20.673	Up-regulation
TK_Src_SrcA_SRC_Y	Q9H5V8	CDCP1	P12931	SRC	Y743	D749Y	749	Missense	distal	6	no	21.825	21.880	EPSD;PhosphoSitePlus	CCLE	20.673	Up-regulation
TK_Src_SrcA_SRC_Y	P41235	HNF4A	P12931	SRC	Y446	G440S	440	Missense	distal	-6	no	20.896	21.039	EPSD	CCLE	20.673	Up-regulation
TK_Src_SrcA_SRC_Y	P41235	HNF4A	P12931	SRC	Y446	G451K	451	Missense	distal	5	no	20.896	20.771	EPSD	CCLE	20.673	Down-regulation
TK_Src_SrcA_SRC_Y	Q12879	GRIN2A	P12931	SRC	Y1184	Y1184C	1184	Missense	central	0	yes	22.095	0.000	EPSD;PhosphoSitePlus	CCLE	20.673	Loss
TK_Src_SrcA_SRC_Y	Q12879	GRIN2A	P12931	SRC	Y1184	L1178F	1178	Missense	distal	-6	no	22.095	22.028	EPSD;PhosphoSitePlus	CCLE	20.673	Down-regulation
TK_Src_SrcA_SRC_Y	Q12879	GRIN2A	P12931	SRC	Y1187	Y1184C	1184	Missense	distal	-3	no	20.698	18.897	EPSD	CCLE	20.673	Loss
TK_Src_SrcA_SRC_Y	Q12879	GRIN2A	P12931	SRC	Y1267	A1272T	1272	Missense	distal	5	no	23.865	24.080	EPSD;PhosphoSitePlus	CCLE	20.673	Up-regulation
TK_Src_SrcA_SRC_Y	P40763	STAT3	P12931	SRC	Y79	L78F	78	Missense	proximal	-1	no	21.754	20.895	EPSD	CCLE	20.673	Down-regulation
TK_Src_SrcA_SRC_Y	P40763	STAT3	P12931	SRC	Y446	H447R	447	Missense	proximal	1	no	21.778	21.852	EPSD	CCLE	20.673	Up-regulation
TK_Src_SrcA_SRC_Y	O15379	HDAC3	P12931	SRC	Y404	P400H	400	Missense	distal	-4	no	22.247	22.086	EPSD	CCLE	20.673	Down-regulation
TK_Src_SrcA_SRC_Y	P52732	KIF11	P12931	SRC	Y399	R393C	393	Missense	distal	-6	no	22.269	21.872	EPSD	CCLE	20.673	Down-regulation
TK_Src_SrcA_SRC_Y	P16885	PLCG2	P12931	SRC	Y1197	Q1202R	1202	Missense	distal	5	no	23.077	23.052	EPSD	CCLE	20.673	Down-regulation
TK_Src_SrcA_SRC_Y	Q96J92	WNK4	P12931	SRC	Y375	E377V	377	Missense	proximal	2	no	20.778	20.809	EPSD	CCLE	20.673	Up-regulation
TK_Src_SrcA_SRC_Y	Q9Y2X7	GIT1	P12931	SRC	Y545	G552R	552	Missense	distal	7	no	22.449	22.456	EPSD	CCLE	20.673	Up-regulation
TK_Src_SrcA_SRC_Y	Q9Y2X7	GIT1	P12931	SRC	Y598	G591S	591	Missense	distal	-7	no	22.344	22.717	EPSD	CCLE	20.673	Up-regulation
TK_Src_SrcA_SRC_Y	Q13480	GAB1	P12931	SRC	Y406	S402Y	402	Missense	distal	-4	no	21.248	21.202	EPSD	CCLE	20.673	Down-regulation
TK_Src_SrcA_SRC_Y	Q13480	GAB1	P12931	SRC	Y447	M450T	450	Missense	distal	3	no	20.885	20.725	EPSD	CCLE	20.673	Down-regulation
TK_Src_SrcA_SRC_Y	Q13480	GAB1	P12931	SRC	Y627	D629E	629	Missense	proximal	2	no	20.464	20.752	EPSD;PhosphoSitePlus	CCLE	20.673	Gain
TK_Src_SrcA_SRC_Y	O43823	AKAP8	P12931	SRC	Y170	N163S	163	Missense	distal	-7	no	21.005	21.037	EPSD;PhosphoSitePlus	CCLE	20.673	Up-regulation
TK_Src_SrcA_SRC_Y	P52757	CHN2	P12931	SRC	Y153	T160A	160	Missense	distal	7	no	23.128	23.148	EPSD	CCLE	20.673	Up-regulation
TK_Src_SrcA_SRC_Y	Q92945	KHSRP	P12931	SRC	Y149	S144L	144	Missense	distal	-5	no	21.215	20.956	EPSD	CCLE	20.673	Down-regulation
TK_Src_SrcA_SRC_Y	Q92945	KHSRP	P12931	SRC	Y583	P590T	590	Missense	distal	7	no	22.049	21.999	PhosphoSitePlus;EPSD	CCLE	20.673	Down-regulation
TK_Src_SrcA_SRC_Y	P61978	HNRNPK	P12931	SRC	Y225	R221C	221	Missense	distal	-4	no	24.096	22.497	EPSD;PhosphoSitePlus	CCLE	20.673	Down-regulation
TK_Src_SrcA_SRC_Y	P61978	HNRNPK	P12931	SRC	Y333	D334N	334	Missense	proximal	1	no	20.981	19.589	EPSD	CCLE	20.673	Loss
TK_Src_SrcA_SRC_Y	P15311	EZR	P12931	SRC	Y116	P118L	118	Missense	proximal	2	no	20.745	20.289	EPSD	CCLE	20.673	Loss
TK_Src_SrcA_SRC_Y	P15311	EZR	P12931	SRC	Y478	V477L	477	Missense	proximal	-1	no	25.069	23.959	PhosphoSitePlus;EPSD	CCLE	20.673	Down-regulation
TK_Src_SrcA_SRC_Y	Q15139	PRKD1	P12931	SRC	Y502	V499L	499	Missense	distal	-3	no	21.516	20.705	EPSD;PhosphoSitePlus	CCLE	20.673	Down-regulation
TK_Src_SrcA_SRC_Y	Q93052	LPP	P12931	SRC	Y287	P291S	291	Missense	distal	4	no	21.800	21.822	EPSD	CCLE	20.673	Up-regulation
TK_Src_SrcA_SRC_Y	Q93052	LPP	P12931	SRC	Y296	P291S	291	Missense	distal	-5	no	21.345	21.447	EPSD	CCLE	20.673	Up-regulation
TK_Src_SrcA_SRC_Y	Q93052	LPP	P12931	SRC	Y297	P291S	291	Missense	distal	-6	no	22.001	22.050	EPSD	CCLE	20.673	Up-regulation
TK_Src_SrcA_SRC_Y	Q9UPT8	ZC3H4	P12931	SRC	Y190	Y196C	196	Missense	distal	6	no	21.179	21.221	EPSD	CCLE	20.673	Up-regulation
TK_Src_SrcA_SRC_Y	Q9UPT8	ZC3H4	P12931	SRC	Y193	Y196C	196	Missense	distal	3	no	21.031	19.955	EPSD	CCLE	20.673	Loss
TK_Src_SrcA_SRC_Y	Q9UPT8	ZC3H4	P12931	SRC	Y196	Y196C	196	Missense	central	0	yes	23.086	0.000	EPSD	CCLE	20.673	Loss
TK_Src_SrcA_SRC_Y	Q9UPT8	ZC3H4	P12931	SRC	Y201	Y196C	196	Missense	distal	-5	no	22.368	22.104	EPSD	CCLE	20.673	Down-regulation
TK_Src_SrcA_SRC_Y	Q9NWQ8	PAG1	P12931	SRC	Y387	I390M	390	Missense	distal	3	no	24.001	23.695	EPSD	CCLE	20.673	Down-regulation
TK_Src_SrcA_SRC_Y	Q16832	DDR2	P12931	SRC	Y740	L735M	735	Missense	distal	-5	no	22.905	22.748	EPSD;PhosphoSitePlus	CCLE	20.673	Down-regulation
TK_Src_SrcA_SRC_Y	Q16832	DDR2	P12931	SRC	Y741	L735M	735	Missense	distal	-6	no	21.636	21.165	EPSD;PhosphoSitePlus	CCLE	20.673	Down-regulation
TK_Src_SrcA_SRC_Y	Q16832	DDR2	P12931	SRC	Y741	V748L	748	Missense	distal	7	no	21.636	21.584	EPSD;PhosphoSitePlus	CCLE	20.673	Down-regulation
TK_Src_SrcA_SRC_Y	Q96RI1	NR1H4	P12931	SRC	Y77	S78C	78	Missense	proximal	1	no	22.496	20.313	PhosphoSitePlus	CCLE	20.673	Loss
TK_Src_SrcA_SRC_Y	O15530	PDPK1	P12931	SRC	Y373	E370K	370	Missense	distal	-3	no	23.167	21.456	EPSD;PhosphoSitePlus	CCLE	20.673	Down-regulation
TK_Src_SrcA_SRC_Y	O15530	PDPK1	P12931	SRC	Y376	E370K	370	Missense	distal	-6	no	21.887	21.874	PhosphoSitePlus;EPSD	CCLE	20.673	Down-regulation
TK_Src_SrcA_SRC_Y	Q15654	TRIP6	P12931	SRC	Y55	G60V	60	Missense	distal	5	no	23.771	23.662	PhosphoSitePlus	CCLE	20.673	Down-regulation
TK_Src_SrcA_SRC_Y	Q9Y613	FHOD1	P12931	SRC	Y176	D173N	173	Missense	distal	-3	no	20.923	20.415	EPSD	CCLE	20.673	Loss
TK_Src_SrcA_SRC_Y	Q9Y613	FHOD1	P12931	SRC	Y439	S433F	433	Missense	distal	-6	no	20.937	20.800	EPSD	CCLE	20.673	Down-regulation
TK_Src_SrcA_SRC_Y	Q9Y613	FHOD1	P12931	SRC	Y878	L877P	877	Missense	proximal	-1	no	23.528	23.542	EPSD	CCLE	20.673	Up-regulation
TK_Src_SrcA_SRC_Y	O75955	FLOT1	P12931	SRC	Y56	V55A	55	Missense	proximal	-1	no	21.289	19.952	EPSD;PhosphoSitePlus	CCLE	20.673	Loss
TK_Src_SrcA_SRC_Y	P12931	SRC	P12931	SRC	Y439	T432M	432	Missense	distal	-7	no	21.282	20.644	EPSD	CCLE	20.673	Loss
TK_Src_SrcA_SRC_Y	Q92556	ELMO1	P12931	SRC	Y511	I517M	517	Missense	distal	6	no	20.767	20.788	EPSD	CCLE	20.673	Up-regulation
TK_Src_SrcA_SRC_Y	P29350	PTPN6	P12931	SRC	Y536	P542L	542	Missense	distal	6	no	23.003	23.019	EPSD;PhosphoSitePlus	CCLE	20.673	Up-regulation
TK_Src_SrcA_SRC_Y	P29350	PTPN6	P12931	SRC	Y564	H568Y	568	Missense	distal	4	no	25.378	25.357	PhosphoSitePlus;EPSD	CCLE	20.673	Down-regulation
TK_Src_SrcA_SRC_Y	P07355	ANXA2	P12931	SRC	Y235	M240V	240	Missense	distal	5	no	21.536	21.241	EPSD	CCLE	20.673	Down-regulation
TK_Src_SrcA_SRC_Y	P07355	ANXA2	P12931	SRC	Y235	S234R	234	Missense	proximal	-1	no	21.536	20.221	EPSD	CCLE	20.673	Loss
TK_Src_SrcA_SRC_Y	P07355	ANXA2	P12931	SRC	Y238	M240V	240	Missense	proximal	2	no	21.411	21.676	EPSD	CCLE	20.673	Up-regulation
TK_Src_SrcA_SRC_Y	P07355	ANXA2	P12931	SRC	Y238	S234R	234	Missense	distal	-4	no	21.411	21.681	EPSD	CCLE	20.673	Up-regulation
TK_Src_SrcA_SRC_Y	P35228	NOS2	P12931	SRC	Y46	N48D	48	Missense	proximal	2	no	20.974	20.760	EPSD	CCLE	20.673	Down-regulation
TK_Src_SrcA_SRC_Y	P35579	MYH9	P12931	SRC	Y754	I756T	756	Missense	proximal	2	no	20.280	21.358	EPSD	CCLE	20.673	Gain
TK_Src_SrcA_SRC_Y	Q9BXP5	SRRT	P12931	SRC	Y8	R12L	12	Missense	distal	4	no	21.784	21.817	EPSD	CCLE	20.673	Up-regulation
TK_Src_SrcA_SRC_Y	Q9BXP5	SRRT	P12931	SRC	Y55	E48K	48	Missense	distal	-7	no	22.374	22.211	EPSD	CCLE	20.673	Down-regulation
TK_Src_SrcA_SRC_Y	Q9BXP5	SRRT	P12931	SRC	Y92	E97K	97	Missense	distal	5	no	21.544	21.576	PhosphoSitePlus;EPSD	CCLE	20.673	Up-regulation
TK_Src_SrcA_SRC_Y	Q9BXP5	SRRT	P12931	SRC	Y92	E97D	97	Missense	distal	5	no	21.544	21.336	PhosphoSitePlus;EPSD	CCLE	20.673	Down-regulation
TK_Src_SrcA_SRC_Y	Q9BXP5	SRRT	P12931	SRC	Y836	Y836S	836	Missense	central	0	yes	21.974	0.000	EPSD;PhosphoSitePlus	CCLE	20.673	Loss
TK_Src_SrcA_SRC_Y	P19367	HK1	P12931	SRC	Y112	H106Y	106	Missense	distal	-6	no	24.626	24.796	EPSD	CCLE	20.673	Up-regulation
TK_Src_SrcA_SRC_Y	P19367	HK1	P12931	SRC	Y112	I118V	118	Missense	distal	6	no	24.626	24.619	EPSD	CCLE	20.673	Down-regulation
TK_Src_SrcA_SRC_Y	P19367	HK1	P12931	SRC	Y732	A736D	736	Missense	distal	4	no	20.803	20.820	PhosphoSitePlus	CCLE	20.673	Up-regulation
TK_Src_SrcA_SRC_Y	Q14247	CTTN	P12931	SRC	Y154	F158V	158	Missense	distal	4	no	21.047	21.029	EPSD	CCLE	20.673	Down-regulation
TK_Src_SrcA_SRC_Y	Q9UGK3	STAP2	P12931	SRC	Y22	E27Q	27	Missense	distal	5	no	23.160	23.161	EPSD;PhosphoSitePlus	CCLE	20.673	Up-regulation
TK_Src_SrcA_SRC_Y	Q9UGK3	STAP2	P12931	SRC	Y250	Y250N	250	Missense	central	0	yes	22.925	0.000	PhosphoSitePlus;EPSD	CCLE	20.673	Loss
TK_Src_SrcA_SRC_Y	Q9UGK3	STAP2	P12931	SRC	Y310	E307Q	307	Missense	distal	-3	no	23.487	22.607	EPSD	CCLE	20.673	Down-regulation
TK_Src_SrcA_SRC_Y	P09327	VIL1	P12931	SRC	Y46	I48T	48	Missense	proximal	2	no	21.304	22.381	EPSD;PhosphoSitePlus	CCLE	20.673	Up-regulation
TK_Src_SrcA_SRC_Y	P31431	SDC4	P12931	SRC	Y180	L182M	182	Missense	proximal	2	no	21.173	21.830	PhosphoSitePlus	CCLE	20.673	Up-regulation
TK_Src_SrcA_SRC_Y	Q9NZQ3	NCKIPSD	P12931	SRC	Y85	R80W	80	Missense	distal	-5	no	20.967	20.302	EPSD	CCLE	20.673	Loss
TK_Src_SrcA_SRC_Y	Q9NZQ3	NCKIPSD	P12931	SRC	Y161	L154I	154	Missense	distal	-7	no	22.909	22.889	EPSD;PhosphoSitePlus	CCLE	20.673	Down-regulation
TK_Src_SrcA_SRC_Y	P08238	HSP90AB1	P12931	SRC	Y155	S160T	160	Missense	distal	5	no	23.633	23.803	EPSD	CCLE	20.673	Up-regulation
TK_Src_SrcA_SRC_Y	P08238	HSP90AB1	P12931	SRC	Y192	R196K	196	Missense	distal	4	no	20.852	20.867	EPSD	CCLE	20.673	Up-regulation
TK_Src_SrcA_SRC_Y	P08238	HSP90AB1	P12931	SRC	Y430	F433L	433	Missense	distal	3	no	21.849	21.608	EPSD	CCLE	20.673	Down-regulation
TK_Src_SrcA_SRC_Y	P10398	ARAF	P12931	SRC	Y42	D37E	37	Missense	distal	-5	no	22.899	23.000	EPSD	CCLE	20.673	Up-regulation
TK_Src_SrcA_SRC_Y	P10398	ARAF	P12931	SRC	Y42	M39K	39	Missense	distal	-3	no	22.899	23.550	EPSD	CCLE	20.673	Up-regulation
TK_Src_SrcA_SRC_Y	P51636	CAV2	P12931	SRC	Y27	E31K	31	Missense	distal	4	no	23.474	23.475	EPSD	CCLE	20.673	Up-regulation
TK_Src_SrcA_SRC_Y	P60953	CDC42	P12931	SRC	Y64	S71T	71	Missense	distal	7	no	21.957	21.927	PhosphoSitePlus	CCLE	20.673	Down-regulation
TK_Src_SrcA_SRC_Y	P07900	HSP90AA1	P12931	SRC	Y160	A161V	161	Missense	proximal	1	no	24.090	23.506	EPSD	CCLE	20.673	Down-regulation
TK_Src_SrcA_SRC_Y	P07900	HSP90AA1	P12931	SRC	Y160	Q159R	159	Missense	proximal	-1	no	24.090	22.258	EPSD	CCLE	20.673	Down-regulation
TK_Src_SrcA_SRC_Y	P07900	HSP90AA1	P12931	SRC	Y197	T195I	195	Missense	proximal	-2	no	20.768	20.024	PhosphoSitePlus	CCLE	20.673	Loss
TK_Src_SrcA_SRC_Y	P07900	HSP90AA1	P12931	SRC	Y309	Y309C	309	Missense	central	0	yes	24.311	0.000	EPSD	CCLE	20.673	Loss
TK_Src_SrcA_SRC_Y	P07900	HSP90AA1	P12931	SRC	Y313	Y309C	309	Missense	distal	-4	no	22.272	20.989	EPSD	CCLE	20.673	Down-regulation
TK_Src_SrcA_SRC_Y	Q8IXJ6	SIRT2	P12931	SRC	Y104	S100F	100	Missense	distal	-4	no	21.286	20.368	PhosphoSitePlus	CCLE	20.673	Loss
TK_Src_SrcA_SRC_Y	Q16595	FXN	P12931	SRC	Y143	P150S	150	Missense	distal	7	no	21.346	21.326	EPSD	CCLE	20.673	Down-regulation
TK_Src_SrcA_SRC_Y	P56945	BCAR1	P12931	SRC	Y249	P253S	253	Missense	distal	4	no	24.404	24.426	EPSD	CCLE	20.673	Up-regulation
TK_Src_SrcA_SRC_Y	P56945	BCAR1	P12931	SRC	Y327	A332T	332	Missense	distal	5	no	24.751	24.966	EPSD	CCLE	20.673	Up-regulation
TK_Src_SrcA_SRC_Y	P56945	BCAR1	P12931	SRC	Y362	V364M	364	Missense	proximal	2	no	25.092	24.827	EPSD	CCLE	20.673	Down-regulation
TK_Src_SrcA_SRC_Y	P56945	BCAR1	P12931	SRC	Y653	Y653H	653	Missense	central	0	yes	23.258	0.000	EPSD	CCLE	20.673	Loss
TK_Src_SrcA_SRC_Y	P56945	BCAR1	P12931	SRC	Y653	D650G	650	Missense	distal	-3	no	23.258	22.609	EPSD	CCLE	20.673	Down-regulation
TK_Src_SrcA_SRC_Y	P56945	BCAR1	P12931	SRC	Y653	P649L	649	Missense	distal	-4	no	23.258	22.623	EPSD	CCLE	20.673	Down-regulation
TK_Src_SrcA_SRC_Y	Q05655	PRKCD	P12931	SRC	Y567	R561H	561	Missense	distal	-6	no	21.050	21.017	EPSD	CCLE	20.673	Down-regulation
TK_Src_SrcA_SRC_Y	P46527	CDKN1B	P12931	SRC	Y88	F87L	87	Missense	proximal	-1	no	21.012	21.871	EPSD;PhosphoSitePlus	CCLE	20.673	Up-regulation
TK_Src_SrcA_SRC_Y	P46527	CDKN1B	P12931	SRC	Y88	Y89C	89	Missense	proximal	1	no	21.012	18.735	EPSD;PhosphoSitePlus	CCLE	20.673	Loss
TK_Src_SrcA_SRC_Y	P46527	CDKN1B	P12931	SRC	Y89	F87L	87	Missense	proximal	-2	no	22.542	22.778	PhosphoSitePlus;EPSD	CCLE	20.673	Up-regulation
TK_Src_SrcA_SRC_Y	P46527	CDKN1B	P12931	SRC	Y89	Y89C	89	Missense	central	0	yes	22.542	0.000	PhosphoSitePlus;EPSD	CCLE	20.673	Loss
TK_Src_SrcA_SRC_Y	Q9NPY3	CD93	P12931	SRC	Y628	P632S	632	Missense	distal	4	no	21.340	21.361	EPSD;PhosphoSitePlus	CCLE	20.673	Up-regulation
TK_Src_SrcA_SRC_Y	Q99704	DOK1	P12931	SRC	Y146	L145M	145	Missense	proximal	-1	no	21.479	20.983	EPSD	CCLE	20.673	Down-regulation
TK_Src_SrcA_SRC_Y	Q9UBS0	RPS6KB2	P12931	SRC	Y45	H44R	44	Missense	proximal	-1	no	21.312	19.417	PhosphoSitePlus	CCLE	20.673	Loss
TK_Src_SrcA_SRC_Y	Q13905	RAPGEF1	P12931	SRC	Y341	S345L	345	Missense	distal	4	no	20.680	20.687	EPSD	CCLE	20.673	Up-regulation
TK_Src_SrcA_SRC_Y	P63010	AP2B1	P12931	SRC	Y888	Q889R	889	Missense	proximal	1	no	21.234	20.241	EPSD	CCLE	20.673	Loss
TK_Src_SrcA_SRC_Y	P63000	RAC1	P12931	SRC	Y64	E62D	62	Missense	proximal	-2	no	21.521	21.233	PhosphoSitePlus	CCLE	20.673	Down-regulation
TK_Src_SrcA_SRC_Y	O15350	TP73	P12931	SRC	Y28	P24L	24	Missense	distal	-4	no	21.706	21.072	PhosphoSitePlus	CCLE	20.673	Down-regulation
TK_Src_SrcA_SRC_Y	O15350	TP73	P12931	SRC	Y99	A100E	100	Missense	proximal	1	no	20.647	21.944	EPSD	CCLE	20.673	Gain
TK_Src_SrcA_SRC_Y	Q96KG7	MEGF10	P12931	SRC	Y1075	V1081M	1081	Missense	distal	6	no	24.403	24.431	EPSD	CCLE	20.673	Up-regulation
TK_Src_SrcA_SRC_Y	Q9P219	CCDC88C	P12931	SRC	Y1272	H1266P	1266	Missense	distal	-6	no	21.980	22.104	EPSD	CCLE	20.673	Up-regulation
TK_Src_SrcA_SRC_Y	P52789	HK2	P12931	SRC	Y417	G414S	414	Missense	distal	-3	no	21.755	21.936	EPSD	CCLE	20.673	Up-regulation
TK_Src_SrcA_SRC_Y	P14921	ETS1	P12931	SRC	Y283	S285R	285	Missense	proximal	2	no	20.953	20.121	PhosphoSitePlus	CCLE	20.673	Loss
TK_Src_SrcA_SRC_Y	P14921	ETS1	P12931	SRC	Y291	S285R	285	Missense	distal	-6	no	21.512	21.372	EPSD	CCLE	20.673	Down-regulation
TK_Src_SrcA_SRC_Y	P23743	DGKA	P12931	SRC	Y669	L672I	672	Missense	distal	3	no	21.351	21.264	EPSD	CCLE	20.673	Down-regulation
TK_Src_SrcA_SRC_Y	Q00987	MDM2	P12931	SRC	Y394	S400N	400	Missense	distal	6	no	25.302	25.285	EPSD	CCLE	20.673	Down-regulation
TK_Src_SrcA_SRC_Y	P36544	CHRNA7	P12931	SRC	Y386	R390C	390	Missense	distal	4	no	21.135	21.136	PhosphoSitePlus;EPSD	CCLE	20.673	Up-regulation
TK_Src_SrcA_SRC_Y	Q9UKW4	VAV3	P12931	SRC	Y141	D139E	139	Missense	proximal	-2	no	24.102	24.389	EPSD	CCLE	20.673	Up-regulation
TK_Src_SrcA_SRC_Y	Q9UKW4	VAV3	P12931	SRC	Y173	M177T	177	Missense	distal	4	no	24.937	24.996	PhosphoSitePlus	CCLE	20.673	Up-regulation
TK_Src_SrcA_SRC_Y	Q9UKW4	VAV3	P12931	SRC	Y173	G170E	170	Missense	distal	-3	no	24.937	25.540	PhosphoSitePlus	CCLE	20.673	Up-regulation
TK_Src_SrcA_SRC_Y	P07949	RET	P12931	SRC	Y900	E902Q	902	Missense	proximal	2	no	22.850	22.541	EPSD	CCLE	20.673	Down-regulation
TK_Src_SrcA_SRC_Y	P07949	RET	P12931	SRC	Y905	E902Q	902	Missense	distal	-3	no	24.148	23.268	PhosphoSitePlus	CCLE	20.673	Down-regulation
TK_Src_SrcA_SRC_Y	P05023	ATP1A1	P12931	SRC	Y10	K3E	3	Missense	distal	-7	no	21.659	21.822	EPSD	CCLE	20.673	Up-regulation
TK_Src_SrcA_SRC_Y	P05023	ATP1A1	P12931	SRC	Y902	I895V	895	Missense	distal	-7	no	20.791	20.775	EPSD	CCLE	20.673	Down-regulation
TK_Src_SrcA_SRC_Y	P37173	TGFBR2	P12931	SRC	Y284	F279L	279	Missense	distal	-5	no	20.631	20.696	PhosphoSitePlus	CCLE	20.673	Gain
TK_Src_SrcA_SRC_Y	P37173	TGFBR2	P12931	SRC	Y470	E471G	471	Missense	proximal	1	no	22.617	21.633	EPSD	CCLE	20.673	Down-regulation
TK_Src_SrcA_SRC_Y	Q9H2X6	HIPK2	P12931	SRC	Y5	P3L	3	Missense	proximal	-2	no	20.836	19.305	EPSD	CCLE	20.673	Loss
TK_Src_SrcA_SRC_Y	Q9H2X6	HIPK2	P12931	SRC	Y5	A2T	2	Missense	distal	-3	no	20.836	21.031	EPSD	CCLE	20.673	Up-regulation
TK_Src_SrcA_SRC_Y	Q9Y446	PKP3	P12931	SRC	Y390	A384V	384	Missense	distal	-6	no	21.488	21.328	EPSD	CCLE	20.673	Down-regulation
TK_Src_SrcA_SRC_Y	Q9Y446	PKP3	P12931	SRC	Y390	R386S	386	Missense	distal	-4	no	21.488	21.218	EPSD	CCLE	20.673	Down-regulation
TK_Src_SrcA_SRC_Y	P31040	SDHA	P12931	SRC	Y604	R600W	600	Missense	distal	-4	no	21.211	19.839	EPSD	CCLE	20.673	Loss
TK_Src_SrcA_SRC_Y	P31040	SDHA	P12931	SRC	Y606	R600W	600	Missense	distal	-6	no	20.944	20.676	EPSD	CCLE	20.673	Down-regulation
TK_Src_SrcA_SRC_Y	O14746	TERT	P12931	SRC	Y949	A956T	956	Missense	distal	7	no	21.333	21.314	EPSD	CCLE	20.673	Down-regulation
TK_Src_SrcA_SRC_Y	O43597	SPRY2	P12931	SRC	Y55	R50P	50	Missense	distal	-5	no	22.341	22.322	PhosphoSitePlus	CCLE	20.673	Down-regulation
TK_Src_SrcA_SRC_Y	Q15746	MYLK	P12931	SRC	Y231	V228M	228	Missense	distal	-3	no	22.717	22.234	EPSD	CCLE	20.673	Down-regulation
TK_Src_SrcA_SRC_Y	P57737	CORO7	P12931	SRC	Y615	R620G	620	Missense	distal	5	no	21.658	21.839	EPSD	CCLE	20.673	Up-regulation
TK_Src_SrcA_SRC_Y	Q14289	PTK2B	P12931	SRC	Y402	E404Q	404	Missense	proximal	2	no	22.034	21.725	PhosphoSitePlus	CCLE	20.673	Down-regulation
TK_Src_SrcA_SRC_Y	P10275	AR	P12931	SRC	Y535	G536R	536	Missense	proximal	1	no	22.172	21.178	PhosphoSitePlus	CCLE	20.673	Down-regulation
TK_Src_SrcA_SRC_Y	O14976	GAK	P12931	SRC	Y371	I377V	377	Missense	distal	6	no	22.598	22.592	EPSD	CCLE	20.673	Down-regulation
TK_Src_SrcA_SRC_Y	O14976	GAK	P12931	SRC	Y371	Y371C	371	Missense	central	0	yes	22.598	0.000	EPSD	CCLE	20.673	Loss
TK_Src_SrcA_SRC_Y	O14976	GAK	P12931	SRC	Y371	D368V	368	Missense	distal	-3	no	22.598	20.674	EPSD	CCLE	20.673	Down-regulation
TK_Src_SrcA_SRC_Y	O14976	GAK	P12931	SRC	Y764	Y764H	764	Missense	central	0	yes	21.459	0.000	EPSD	CCLE	20.673	Loss
TK_Src_SrcA_SRC_Y	O14976	GAK	P12931	SRC	Y764	Q757H	757	Missense	distal	-7	no	21.459	21.388	EPSD	CCLE	20.673	Down-regulation
TK_Src_SrcA_SRC_Y	A1X283	SH3PXD2B	P12931	SRC	Y226	E222V	222	Missense	distal	-4	no	22.598	21.349	EPSD	CCLE	20.673	Down-regulation
TK_Src_SrcA_SRC_Y	A1X283	SH3PXD2B	P12931	SRC	Y226	E222K	222	Missense	distal	-4	no	22.598	21.428	EPSD	CCLE	20.673	Down-regulation
TK_Src_SrcA_SRC_Y	P06493	CDK1	P12931	SRC	Y15	K9N	9	Missense	distal	-6	no	24.693	24.593	PhosphoSitePlus	CCLE	20.673	Down-regulation
TK_Src_SrcA_SRC_Y	Q3V6T2	CCDC88A	P12931	SRC	Y1153	D1154E	1154	Missense	proximal	1	no	21.553	22.159	EPSD	CCLE	20.673	Up-regulation
TK_Src_SrcA_SRC_Y	Q07954	LRP1	P12931	SRC	Y4507	G4514A	4514	Missense	distal	7	no	23.612	23.570	EPSD;PhosphoSitePlus	CCLE	20.673	Down-regulation
TK_Src_SrcA_SRC_Y	Q16625	OCLN	P12931	SRC	Y368	Q365K	365	Missense	distal	-3	no	20.918	20.087	EPSD	CCLE	20.673	Loss
TK_Src_SrcA_SRC_Y	Q99439	CNN2	P12931	SRC	Y12	V18G	18	Missense	distal	6	no	21.761	21.767	PhosphoSitePlus	CCLE	20.673	Up-regulation
TK_Src_SrcA_SRC_Y	Q99439	CNN2	P12931	SRC	Y303	A307V	307	Missense	distal	4	no	21.700	21.673	EPSD	CCLE	20.673	Down-regulation
TK_Src_SrcA_SRC_Y	Q969H4	CNKSR1	P12931	SRC	Y665	Y665C	665	Missense	central	0	yes	21.467	0.000	EPSD;PhosphoSitePlus	CCLE	20.673	Loss
TK_Src_SrcA_SRC_Y	Q00610	CLTC	P12931	SRC	Y377	A384D	384	Missense	distal	7	no	20.794	20.774	EPSD	CCLE	20.673	Down-regulation
TK_Src_SrcA_SRC_Y	Q00610	CLTC	P12931	SRC	Y1137	M1138V	1138	Missense	proximal	1	no	21.484	22.107	EPSD	CCLE	20.673	Up-regulation
TK_Src_SrcA_SRC_Y	Q00610	CLTC	P12931	SRC	Y1168	K1162N	1162	Missense	distal	-6	no	21.336	21.235	EPSD	CCLE	20.673	Down-regulation
TK_Src_SrcA_SRC_Y	Q00610	CLTC	P12931	SRC	Y1206	E1208D	1208	Missense	proximal	2	no	20.975	20.688	EPSD	CCLE	20.673	Down-regulation
TK_Src_SrcA_SRC_Y	Q00610	CLTC	P12931	SRC	Y1634	M1640T	1640	Missense	distal	6	no	20.961	20.910	EPSD	CCLE	20.673	Down-regulation
TK_Src_SrcA_SRC_Y	P11802	CDK4	P12931	SRC	Y17	E11G	11	Missense	distal	-6	no	22.818	22.589	PhosphoSitePlus	CCLE	20.673	Down-regulation
TK_Src_SrcA_SRC_Y	P35968	KDR	P12931	SRC	Y224	Y224H	224	Missense	central	0	yes	20.745	0.000	EPSD	CCLE	20.673	Loss
TK_Src_SrcA_SRC_Y	P00519	ABL1	P12931	SRC	Y185	A179V	179	Missense	distal	-6	no	23.126	22.965	EPSD	CCLE	20.673	Down-regulation
TK_Src_SrcA_SRC_Y	P00519	ABL1	P12931	SRC	Y226	T224I	224	Missense	proximal	-2	no	21.982	21.239	EPSD	CCLE	20.673	Down-regulation
TK_Src_SrcA_SRC_Y	Q8WWM7	ATXN2L	P12931	SRC	Y145	N141Y	141	Missense	distal	-4	no	21.256	20.795	EPSD	CCLE	20.673	Down-regulation
TK_Src_SrcA_SRC_Y	Q8WWM7	ATXN2L	P12931	SRC	Y349	A343V	343	Missense	distal	-6	no	20.848	20.688	EPSD	CCLE	20.673	Down-regulation
TK_Src_SrcA_SRC_Y	Q8WWM7	ATXN2L	P12931	SRC	Y349	G347E	347	Missense	proximal	-2	no	20.848	21.425	EPSD	CCLE	20.673	Up-regulation
TK_Src_SrcA_SRC_Y	Q13017	ARHGAP5	P12931	SRC	Y630	P636L	636	Missense	distal	6	no	24.121	24.137	EPSD	CCLE	20.673	Up-regulation
TK_Src_SrcA_SRC_Y	P49023	PXN	P12931	SRC	Y181	S178N	178	Missense	distal	-3	no	22.194	22.153	EPSD	CCLE	20.673	Down-regulation
TK_Src_SrcA_SRC_Y	Q6UN15	FIP1L1	P12931	SRC	Y27	V33M	33	Missense	distal	6	no	21.068	21.096	EPSD	CCLE	20.673	Up-regulation
TK_Src_SrcA_SRC_Y	O15259	NPHP1	P12931	SRC	Y46	Q43P	43	Missense	distal	-3	no	21.083	20.422	EPSD	CCLE	20.673	Loss
TK_Src_SrcA_SRC_Y	P10636	MAPT	P12931	SRC	Y514	R511H	511	Missense	distal	-3	no	21.389	21.354	EPSD	CCLE	20.673	Down-regulation
TK_Src_SrcA_SRC_Y	P10636	MAPT	P12931	SRC	Y514	G518S	518	Missense	distal	4	no	21.389	21.414	EPSD	CCLE	20.673	Up-regulation
TK_Src_SrcA_SRC_Y	P10636	MAPT	P12931	SRC	Y711	G706V	706	Missense	distal	-5	no	22.032	22.003	EPSD	CCLE	20.673	Down-regulation
TK_Src_SrcA_SRC_Y	P10636	MAPT	P12931	SRC	Y711	S717C	717	Missense	distal	6	no	22.032	22.107	EPSD	CCLE	20.673	Up-regulation
TK_Src_SrcA_SRC_Y	P78352	DLG4	P12931	SRC	Y236	T235A	235	Missense	proximal	-1	no	21.012	21.029	EPSD	CCLE	20.673	Up-regulation
TK_Src_SrcA_SRC_Y	P78352	DLG4	P12931	SRC	Y236	L232P	232	Missense	distal	-4	no	21.012	21.647	EPSD	CCLE	20.673	Up-regulation
TK_Src_SrcA_SRC_Y	P78352	DLG4	P12931	SRC	Y397	E401G	401	Missense	distal	4	no	21.654	21.641	EPSD	CCLE	20.673	Down-regulation
TK_Src_SrcA_SRC_Y	P78352	DLG4	P12931	SRC	Y397	F400L	400	Missense	distal	3	no	21.654	21.413	EPSD	CCLE	20.673	Down-regulation
TK_Src_SrcA_SRC_Y	P78352	DLG4	P12931	SRC	Y523	V526M	526	Missense	distal	3	no	20.976	20.609	PhosphoSitePlus	CCLE	20.673	Loss
TK_Src_SrcA_SRC_Y	P78352	DLG4	P12931	SRC	Y604	L608I	608	Missense	distal	4	no	21.886	21.862	EPSD	CCLE	20.673	Down-regulation
TK_Src_SrcA_SRC_Y	P50281	MMP14	P12931	SRC	Y138	E142K	142	Missense	distal	4	no	22.285	22.286	EPSD	CCLE	20.673	Up-regulation
TK_Src_SrcA_SRC_Y	O43613	HCRTR1	P12931	SRC	Y27	R33H	33	Missense	distal	6	no	21.876	21.905	EPSD	CCLE	20.673	Up-regulation
CMGC_CDK_CDK2_CDK3_ST	Q14934	NFATC4	Q00526	CDK3	S168	S174N	174	Missense	distal	6	no	10.053	10.105	EPSD	CCLE	5.767	Up-regulation
CMGC_CDK_CDK2_CDK3_ST	Q14934	NFATC4	Q00526	CDK3	S170	S174N	174	Missense	distal	4	no	9.473	9.424	EPSD	CCLE	5.767	Down-regulation
CMGC_CDK_CDK2_CDK3_ST	Q14934	NFATC4	Q00526	CDK3	S217	S221F	221	Missense	distal	4	no	9.066	8.953	EPSD	CCLE	5.767	Down-regulation
CMGC_CDK_CDK2_CDK3_ST	Q14934	NFATC4	Q00526	CDK3	S221	S221F	221	Missense	central	0	yes	10.708	0.000	EPSD	CCLE	5.767	Loss
CMGC_CDK_CDK2_CDK3_ST	Q14934	NFATC4	Q00526	CDK3	T226	S221F	221	Missense	distal	-5	no	7.527	8.366	EPSD	CCLE	5.767	Up-regulation
CMGC_CDK_CDK2_CDK3_ST	Q14934	NFATC4	Q00526	CDK3	S592	A590T	590	Missense	proximal	-2	no	8.336	8.443	EPSD	CCLE	5.767	Up-regulation
CMGC_CDK_CDK2_CDK3_ST	Q14934	NFATC4	Q00526	CDK3	S716	P720L	720	Missense	distal	4	no	10.253	10.259	EPSD	CCLE	5.767	Up-regulation
CMGC_CDK_CDK2_CDK3_ST	Q14934	NFATC4	Q00526	CDK3	S819	P820L	820	Missense	proximal	1	no	8.863	2.118	EPSD	CCLE	5.767	Loss
CMGC_CDK_CDK2_CDK3_ST	P03372	ESR1	Q00526	CDK3	S102	F97S	97	Missense	distal	-5	no	6.023	5.184	EPSD	CCLE	5.767	Loss
CMGC_CDK_CDK2_CDK3_ST	P03372	ESR1	Q00526	CDK3	S104	F97S	97	Missense	distal	-7	no	14.135	13.740	EPSD;PhosphoSitePlus	CCLE	5.767	Down-regulation
CMGC_CDK_CDK2_CDK3_ST	P03372	ESR1	Q00526	CDK3	S294	M297I	297	Missense	distal	3	no	9.470	8.856	EPSD	CCLE	5.767	Down-regulation
CMGC_CDK_CDK2_CDK3_ST	P46531	NOTCH1	Q00526	CDK3	T1986	R1991C	1991	Missense	distal	5	no	6.356	6.258	EPSD	CCLE	5.767	Down-regulation
CMGC_CDK_CDK2_CDK3_ST	P46531	NOTCH1	Q00526	CDK3	T1997	R1991C	1991	Missense	distal	-6	no	7.292	7.131	EPSD	CCLE	5.767	Down-regulation
CMGC_CDK_CDK2_CDK3_ST	P18846	ATF1	Q00526	CDK3	S63	R60Q	60	Missense	distal	-3	no	14.522	14.388	PhosphoSitePlus	CCLE	5.767	Down-regulation
CMGC_CDK_CDK2_CDK3_ST	P18846	ATF1	Q00526	CDK3	S63	I67F	67	Missense	distal	4	no	14.522	14.547	PhosphoSitePlus	CCLE	5.767	Up-regulation
CMGC_CDK_CDK2_CDK3_ST	P18846	ATF1	Q00526	CDK3	S72	I67F	67	Missense	distal	-5	no	7.813	7.529	EPSD	CCLE	5.767	Down-regulation
CMGC_CDK_CDK2_CDK3_ST	P18846	ATF1	Q00526	CDK3	S72	R77W	77	Missense	distal	5	no	7.813	7.637	EPSD	CCLE	5.767	Down-regulation
CMGC_CDK_CDK2_CDK3_ST	P06400	RB1	Q00526	CDK3	T373	M379T	379	Missense	distal	6	no	6.520	6.504	EPSD	CCLE	5.767	Down-regulation
CMGC_CDK_CDK2_CDK3_ST	P06400	RB1	Q00526	CDK3	S608	P609H	609	Missense	proximal	1	no	6.784	0.686	EPSD	CCLE	5.767	Loss
CMGC_CDK_CDK2_CDK3_ST	P06400	RB1	Q00526	CDK3	S612	P609H	609	Missense	distal	-3	no	10.432	10.574	EPSD	CCLE	5.767	Up-regulation
Other_WNK_WNK2_ST	Q9H4A3	WNK1	Q9Y3S1	WNK2	S597	V593A	593	Missense	distal	-4	no	2.940	2.945	EPSD	CCLE	2.413	Up-regulation
Other_WNK_WNK2_ST	Q9H4A3	WNK1	Q9Y3S1	WNK2	S1110	R1117C	1117	Missense	distal	7	no	2.149	2.530	EPSD	CCLE	2.413	Gain
Other_WNK_WNK2_ST	Q9H4A3	WNK1	Q9Y3S1	WNK2	T1115	R1117C	1117	Missense	proximal	2	no	2.453	2.441	EPSD	CCLE	2.413	Down-regulation
AGC_RSK_MSK_RPS6KA4_ST	P54253	ATXN1	O75676	RPS6KA4	S262	A261T	261	Missense	proximal	-1	no	3.049	3.016	EPSD	CCLE	2.457	Down-regulation
AGC_RSK_MSK_RPS6KA4_ST	P54253	ATXN1	O75676	RPS6KA4	S775	A768V	768	Missense	distal	-7	no	4.941	4.856	PhosphoSitePlus	CCLE	2.457	Down-regulation
AGC_RSK_MSK_RPS6KA4_ST	Q04206	RELA	O75676	RPS6KA4	S338	S340F	340	Missense	proximal	2	no	4.164	4.174	EPSD	CCLE	2.457	Up-regulation
AGC_RSK_MSK_RPS6KA4_ST	Q04206	RELA	O75676	RPS6KA4	S340	S340F	340	Missense	central	0	yes	2.941	0.000	EPSD	CCLE	2.457	Loss
AGC_RSK_MSK_RPS6KA4_ST	O75676	RPS6KA4	O75676	RPS6KA4	S433	G434S	434	Missense	proximal	1	no	3.104	3.065	EPSD	CCLE	2.457	Down-regulation
AGC_RSK_MSK_RPS6KA4_ST	O75676	RPS6KA4	O75676	RPS6KA4	S433	A438T	438	Missense	distal	5	no	3.104	2.924	EPSD	CCLE	2.457	Down-regulation
AGC_RSK_MSK_RPS6KA4_ST	O75676	RPS6KA4	O75676	RPS6KA4	S671	G677S	677	Missense	distal	6	no	3.640	3.459	EPSD	CCLE	2.457	Down-regulation
AGC_RSK_MSK_RPS6KA4_ST	O75676	RPS6KA4	O75676	RPS6KA4	S682	G677S	677	Missense	distal	-5	no	3.084	3.144	EPSD	CCLE	2.457	Up-regulation
AGC_RSK_MSK_RPS6KA4_ST	O75676	RPS6KA4	O75676	RPS6KA4	S682	A679E	679	Missense	distal	-3	no	3.084	2.469	EPSD	CCLE	2.457	Down-regulation
AGC_RSK_MSK_RPS6KA4_ST	O75676	RPS6KA4	O75676	RPS6KA4	S745	R743W	743	Missense	proximal	-2	no	3.872	1.866	EPSD	CCLE	2.457	Loss
TKL_MLK_ILK_ILK_ST	E9PAV3	NACA	Q13418	ILK	T1339	P1343H	1343	Missense	distal	4	no	16.295	16.358	EPSD	CCLE	15.108	Up-regulation
TKL_MLK_ILK_ILK_ST	E9PAV3	NACA	Q13418	ILK	T1339	P1343S	1343	Missense	distal	4	no	16.295	16.418	EPSD	CCLE	15.108	Up-regulation
TKL_MLK_ILK_ILK_ST	E9PAV3	NACA	Q13418	ILK	S1581	P1574A	1574	Missense	distal	-7	no	16.375	16.380	EPSD	CCLE	15.108	Up-regulation
TKL_MLK_ILK_ILK_ST	E9PAV3	NACA	Q13418	ILK	T1636	V1642E	1642	Missense	distal	6	no	16.225	17.181	EPSD	CCLE	15.108	Up-regulation
TKL_MLK_ILK_ILK_ST	E9PAV3	NACA	Q13418	ILK	T1636	A1632V	1632	Missense	distal	-4	no	16.225	15.783	EPSD	CCLE	15.108	Down-regulation
CK1_VRK_VRK1_ST	P05412	JUN	Q99986	VRK1	S58	R54G	54	Missense	distal	-4	no	0.311	0.280	EPSD	CCLE	0.296	Loss
CK1_VRK_VRK1_ST	P15336	ATF2	Q99986	VRK1	T73	R74K	74	Missense	proximal	1	no	0.514	0.519	EPSD;PhosphoSitePlus	CCLE	0.296	Up-regulation
CK1_VRK_VRK1_ST	P15336	ATF2	Q99986	VRK1	T305	S307L	307	Missense	proximal	2	no	0.369	0.322	EPSD	CCLE	0.296	Down-regulation
CK1_VRK_VRK1_ST	P04637	TP53	Q99986	VRK1	S149	P142R	142	Missense	distal	-7	no	0.377	0.354	EPSD	CCLE	0.296	Down-regulation
AGC_PKC_PKCi_PRKCI_ST	Q4VCS5	AMOT	P41743	PRKCI	T750	I755S	755	Missense	distal	5	no	9.318	9.399	EPSD;PhosphoSitePlus	CCLE	6.376	Up-regulation
AGC_PKC_PKCi_PRKCI_ST	P08151	GLI1	P41743	PRKCI	S201	P202H	202	Missense	proximal	1	no	8.249	7.106	EPSD	CCLE	6.376	Down-regulation
AGC_PKC_PKCi_PRKCI_ST	P08151	GLI1	P41743	PRKCI	S201	G206C	206	Missense	distal	5	no	8.249	8.081	EPSD	CCLE	6.376	Down-regulation
AGC_PKC_PKCi_PRKCI_ST	P10636	MAPT	P41743	PRKCI	T71	A66V	66	Missense	distal	-5	no	7.912	6.432	EPSD	CCLE	6.376	Down-regulation
AGC_PKC_PKCi_PRKCI_ST	P10636	MAPT	P41743	PRKCI	S214	D221Y	221	Missense	distal	7	no	10.639	10.649	EPSD	CCLE	6.376	Up-regulation
AGC_PKC_PKCi_PRKCI_ST	P10636	MAPT	P41743	PRKCI	S447	V442I	442	Missense	distal	-5	no	6.735	6.699	EPSD	CCLE	6.376	Down-regulation
AGC_PKC_PKCi_PRKCI_ST	P10636	MAPT	P41743	PRKCI	S531	R526L	526	Missense	distal	-5	no	8.198	4.883	EPSD	CCLE	6.376	Loss
AGC_PKC_PKCi_PRKCI_ST	P10636	MAPT	P41743	PRKCI	S575	K574N	574	Missense	proximal	-1	no	8.591	8.354	EPSD	CCLE	6.376	Down-regulation
AGC_PKC_PKCi_PRKCI_ST	P10636	MAPT	P41743	PRKCI	S739	Q741K	741	Missense	proximal	2	no	6.466	6.247	EPSD	CCLE	6.376	Loss
AGC_PKC_PKCi_PRKCI_ST	Q13464	ROCK1	P41743	PRKCI	T9	M14I	14	Missense	distal	5	no	6.448	6.177	EPSD	CCLE	6.376	Loss
AGC_PKC_PKCi_PRKCI_ST	Q13464	ROCK1	P41743	PRKCI	T890	A895E	895	Missense	distal	5	no	7.158	7.247	EPSD	CCLE	6.376	Up-regulation
AGC_PKC_PKCi_PRKCI_ST	Q13464	ROCK1	P41743	PRKCI	S1333	Q1340E	1340	Missense	distal	7	no	6.478	6.493	EPSD;PhosphoSitePlus	CCLE	6.376	Up-regulation
AGC_PKC_PKCi_PRKCI_ST	Q13464	ROCK1	P41743	PRKCI	S1341	Q1340E	1340	Missense	proximal	-1	no	8.401	8.363	EPSD;PhosphoSitePlus	CCLE	6.376	Down-regulation
AGC_PKC_PKCi_PRKCI_ST	Q92934	BAD	P41743	PRKCI	S25	S32L	32	Missense	distal	7	no	8.959	8.809	EPSD	CCLE	6.376	Down-regulation
AGC_PKC_PKCi_PRKCI_ST	Q92934	BAD	P41743	PRKCI	S75	H73Q	73	Missense	proximal	-2	no	9.961	9.890	PhosphoSitePlus;EPSD	CCLE	6.376	Down-regulation
AGC_PKC_PKCi_PRKCI_ST	Q92934	BAD	P41743	PRKCI	S75	R70W	70	Missense	distal	-5	no	9.961	5.318	PhosphoSitePlus;EPSD	CCLE	6.376	Loss
AGC_PKC_PKCi_PRKCI_ST	Q13118	KLF10	P41743	PRKCI	T445	H451R	451	Missense	distal	6	no	9.688	9.893	EPSD;PhosphoSitePlus	CCLE	6.376	Up-regulation
AGC_PKC_PKCi_PRKCI_ST	Q13118	KLF10	P41743	PRKCI	T445	M439T	439	Missense	distal	-6	no	9.688	9.721	EPSD;PhosphoSitePlus	CCLE	6.376	Up-regulation
AGC_PKC_PKCi_PRKCI_ST	Q15910	EZH2	P41743	PRKCI	S8	C14Y	14	Missense	distal	6	no	9.834	10.010	EPSD	CCLE	6.376	Up-regulation
AGC_PKC_PKCi_PRKCI_ST	Q15910	EZH2	P41743	PRKCI	S21	C14Y	14	Missense	distal	-7	no	11.389	10.661	EPSD	CCLE	6.376	Down-regulation
AGC_PKC_PKCi_PRKCI_ST	Q15910	EZH2	P41743	PRKCI	S690	Y696C	696	Missense	distal	6	no	11.100	10.924	EPSD;PhosphoSitePlus	CCLE	6.376	Down-regulation
AGC_PKC_PKCi_PRKCI_ST	Q14247	CTTN	P41743	PRKCI	S109	S106L	106	Missense	distal	-3	no	7.813	5.976	EPSD	CCLE	6.376	Loss
AGC_PKC_PKCi_PRKCI_ST	Q14247	CTTN	P41743	PRKCI	S113	S106L	106	Missense	distal	-7	no	6.589	7.365	EPSD	CCLE	6.376	Up-regulation
AGC_PKC_PKCi_PRKCI_ST	Q14247	CTTN	P41743	PRKCI	S192	G196S	196	Missense	distal	4	no	6.786	6.441	EPSD	CCLE	6.376	Down-regulation
AGC_PKC_PKCi_PRKCI_ST	Q14247	CTTN	P41743	PRKCI	S282	G286E	286	Missense	distal	4	no	6.776	6.466	EPSD	CCLE	6.376	Down-regulation
AGC_PKC_PKCi_PRKCI_ST	P27448	MARK3	P41743	PRKCI	S400	K404E	404	Missense	distal	4	no	6.466	6.346	EPSD	CCLE	6.376	Loss
AGC_PKC_PKCi_PRKCI_ST	P27448	MARK3	P41743	PRKCI	S724	L723P	723	Missense	proximal	-1	no	8.174	8.217	EPSD	CCLE	6.376	Up-regulation
AGC_PKC_PKCi_PRKCI_ST	P27448	MARK3	P41743	PRKCI	S734	R732W	732	Missense	proximal	-2	no	8.630	7.491	EPSD	CCLE	6.376	Down-regulation
AGC_PKC_PKCi_PRKCI_ST	Q8TEW0	PARD3	P41743	PRKCI	S386	S380N	380	Missense	distal	-6	no	8.859	9.137	EPSD	CCLE	6.376	Up-regulation
AGC_PKC_PKCi_PRKCI_ST	Q8TEW0	PARD3	P41743	PRKCI	T468	G470S	470	Missense	proximal	2	no	7.257	7.551	EPSD	CCLE	6.376	Up-regulation
AGC_PKC_PKCi_PRKCI_ST	Q8TEW0	PARD3	P41743	PRKCI	S529	K535N	535	Missense	distal	6	no	7.752	7.636	EPSD	CCLE	6.376	Down-regulation
AGC_PKC_PKCi_PRKCI_ST	P78545	ELF3	P41743	PRKCI	S68	Q71L	71	Missense	distal	3	no	9.480	9.934	PhosphoSitePlus	CCLE	6.376	Up-regulation
AGC_PKC_PKCi_PRKCI_ST	Q16236	NFE2L2	P41743	PRKCI	S301	P300S	300	Missense	proximal	-1	no	6.676	6.730	EPSD	CCLE	6.376	Up-regulation
AGC_PKC_PKCi_PRKCI_ST	Q9H8V3	ECT2	P41743	PRKCI	S443	P445A	445	Missense	proximal	2	no	8.358	8.772	EPSD	CCLE	6.376	Up-regulation
AGC_PKC_PKCi_PRKCI_ST	Q9H8V3	ECT2	P41743	PRKCI	S448	P445A	445	Missense	distal	-3	no	6.742	8.482	EPSD	CCLE	6.376	Up-regulation
TK_Syk_ZAP70_Y	Q9UQC2	GAB2	P43403	ZAP70	Y194	P189S	189	Missense	distal	-5	no	6.412	6.408	EPSD	CCLE	5.220	Down-regulation
TK_Syk_ZAP70_Y	P51452	DUSP3	P43403	ZAP70	Y38	V39A	39	Missense	proximal	1	no	11.680	9.982	EPSD;PhosphoSitePlus	CCLE	5.220	Down-regulation
TK_Syk_ZAP70_Y	P51452	DUSP3	P43403	ZAP70	Y38	Y38H	38	Missense	central	0	yes	11.680	0.000	EPSD;PhosphoSitePlus	CCLE	5.220	Loss
Atypical_BCR_BCR_ST	P27348	YWHAQ	P11274	BCR	S232	A233V	233	Missense	proximal	1	no	17.130	16.886	PhosphoSitePlus	CCLE	1.927	Down-regulation
Other_WEE_Myt1_PKMYT1_ST	P06493	CDK1	Q99640	PKMYT1	T14	K9N	9	Missense	distal	-5	no	4.767	4.761	PhosphoSitePlus;EPSD	CCLE	1.669	Down-regulation
Other_NEK_NEK6_NEK7_ST	Q15058	KIF14	Q8TDX7	NEK7	S1466	G1462E	1462	Missense	distal	-4	no	3.633	3.577	EPSD	CCLE	3.120	Down-regulation
Other_NEK_NEK6_NEK7_ST	P54274	TERF1	Q8TDX7	NEK7	S404	Y398H	398	Missense	distal	-6	no	3.291	3.563	EPSD	CCLE	3.120	Up-regulation
TKL_STKR_STKR1_BMPR1B_ST	Q15797	SMAD1	O00238	BMPR1B	S462	P460S	460	Missense	proximal	-2	no	-0.890	-0.892	EPSD;PhosphoSitePlus	CCLE	-1.120	Down-regulation
TKL_STKR_STKR1_BMPR1B_ST	Q15797	SMAD1	O00238	BMPR1B	S465	P460S	460	Missense	distal	-5	no	-0.836	-0.841	PhosphoSitePlus;EPSD	CCLE	-1.120	Down-regulation
TK_Fak_PTK2B_Y	O15259	NPHP1	Q14289	PTK2B	Y46	Q43P	43	Missense	distal	-3	no	510.001	446.865	EPSD;PhosphoSitePlus	CCLE	366.093	Down-regulation
TK_Fak_PTK2B_Y	Q14247	CTTN	Q14289	PTK2B	Y199	G196S	196	Missense	distal	-3	no	357.445	454.565	EPSD	CCLE	366.093	Gain
TK_Fak_PTK2B_Y	Q14289	PTK2B	Q14289	PTK2B	Y402	E404Q	404	Missense	proximal	2	no	715.215	714.707	PhosphoSitePlus	CCLE	366.093	Down-regulation
AGC_RSK_RSKp70_RPS6KB2_ST	P04792	HSPB1	Q9UBS0	RPS6KB2	S82	S78T	78	Missense	distal	-4	no	9.866	9.698	EPSD;PhosphoSitePlus	CCLE	4.103	Down-regulation
AGC_RSK_RSKp70_RPS6KB2_ST	P04792	HSPB1	Q9UBS0	RPS6KB2	T174	E178Q	178	Missense	distal	4	no	4.127	4.138	EPSD	CCLE	4.103	Up-regulation
AGC_RSK_RSKp70_RPS6KB2_ST	P49841	GSK3B	Q9UBS0	RPS6KB2	S147	T152M	152	Missense	distal	5	no	5.899	5.953	EPSD	CCLE	4.103	Up-regulation
AGC_RSK_RSKp70_RPS6KB2_ST	O00418	EEF2K	Q9UBS0	RPS6KB2	S366	S359C	359	Missense	distal	-7	no	9.928	10.118	PhosphoSitePlus	CCLE	4.103	Up-regulation
AGC_RSK_RSKp70_RPS6KB2_ST	P09651	HNRNPA1	Q9UBS0	RPS6KB2	S182	K179R	179	Missense	distal	-3	no	5.921	8.627	EPSD	CCLE	4.103	Up-regulation
AGC_RSK_RSKp70_RPS6KB2_ST	P09651	HNRNPA1	Q9UBS0	RPS6KB2	S182	E185Q	185	Missense	distal	3	no	5.921	5.906	EPSD	CCLE	4.103	Down-regulation
AGC_RSK_RSKp70_RPS6KB2_ST	P09651	HNRNPA1	Q9UBS0	RPS6KB2	S197	N201K	201	Missense	distal	4	no	6.020	6.052	EPSD	CCLE	4.103	Up-regulation
AGC_RSK_RSKp70_RPS6KB2_ST	P09651	HNRNPA1	Q9UBS0	RPS6KB2	S199	N201K	201	Missense	proximal	2	no	7.042	6.983	EPSD	CCLE	4.103	Down-regulation
AGC_RSK_RSKp70_RPS6KB2_ST	Q6R327	RICTOR	Q9UBS0	RPS6KB2	S21	V15I	15	Missense	distal	-6	no	6.466	6.453	EPSD	CCLE	4.103	Down-regulation
AGC_RSK_RSKp70_RPS6KB2_ST	Q6R327	RICTOR	Q9UBS0	RPS6KB2	S585	K582N	582	Missense	distal	-3	no	4.137	1.623	EPSD	CCLE	4.103	Loss
AGC_RSK_RSKp70_RPS6KB2_ST	Q6R327	RICTOR	Q9UBS0	RPS6KB2	S1122	K1119E	1119	Missense	distal	-3	no	5.186	2.522	EPSD	CCLE	4.103	Loss
AGC_RSK_RSKp70_RPS6KB2_ST	Q6R327	RICTOR	Q9UBS0	RPS6KB2	S1302	A1309T	1309	Missense	distal	7	no	5.813	5.817	EPSD	CCLE	4.103	Up-regulation
TK_Src_SrcA_FGR_Y	Q9UHD2	TBK1	P09769	FGR	Y340	I334L	334	Missense	distal	-6	no	5.205	5.222	EPSD	CCLE	5.114	Up-regulation
TK_Src_SRM_PTK6_Y	Q13882	PTK6	Q13882	PTK6	Y66	R70K	70	Missense	distal	4	no	35.898	35.660	EPSD	CCLE	13.984	Down-regulation
TK_Src_SRM_PTK6_Y	Q13882	PTK6	Q13882	PTK6	Y351	A358T	358	Missense	distal	7	no	21.722	22.021	EPSD	CCLE	13.984	Up-regulation
TK_Src_SRM_PTK6_Y	Q9UGK3	STAP2	Q13882	PTK6	Y21	E27Q	27	Missense	distal	6	no	18.605	19.286	EPSD	CCLE	13.984	Up-regulation
TK_Src_SRM_PTK6_Y	Q9UGK3	STAP2	Q13882	PTK6	Y250	Y250N	250	Missense	central	0	yes	28.373	0.000	PhosphoSitePlus	CCLE	13.984	Loss
TK_Src_SRM_PTK6_Y	Q9UGK3	STAP2	Q13882	PTK6	Y310	E307Q	307	Missense	distal	-3	no	16.841	15.273	EPSD	CCLE	13.984	Down-regulation
TK_Src_SRM_PTK6_Y	P56945	BCAR1	Q13882	PTK6	Y327	A332T	332	Missense	distal	5	no	14.282	12.908	EPSD	CCLE	13.984	Loss
TK_Src_SRM_PTK6_Y	P49023	PXN	Q13882	PTK6	Y181	S178N	178	Missense	distal	-3	no	15.662	14.654	EPSD	CCLE	13.984	Down-regulation
Other_ULK_ULK_ULK1_ST	Q16543	CDC37	O75385	ULK1	S140	E141Q	141	Missense	proximal	1	no	34.433	34.440	EPSD	CCLE	29.179	Up-regulation
Other_ULK_ULK_ULK1_ST	Q16543	CDC37	O75385	ULK1	S377	K374M	374	Missense	distal	-3	no	19.367	37.200	EPSD	CCLE	29.179	Gain
Other_ULK_ULK_ULK1_ST	Q8N122	RPTOR	O75385	ULK1	S8	E2Q	2	Missense	distal	-6	no	47.595	45.871	EPSD	CCLE	29.179	Down-regulation
Other_ULK_ULK_ULK1_ST	Q7Z3C6	ATG9A	O75385	ULK1	S759	P757S	757	Missense	proximal	-2	no	26.929	32.989	EPSD	CCLE	29.179	Gain
Other_ULK_ULK_ULK1_ST	Q7Z3C6	ATG9A	O75385	ULK1	S761	R758P	758	Missense	distal	-3	no	39.220	31.859	PhosphoSitePlus;EPSD	CCLE	29.179	Down-regulation
Other_ULK_ULK_ULK1_ST	Q7Z3C6	ATG9A	O75385	ULK1	S761	P757S	757	Missense	distal	-4	no	39.220	40.609	PhosphoSitePlus;EPSD	CCLE	29.179	Up-regulation
Other_ULK_ULK_ULK1_ST	Q7Z3C6	ATG9A	O75385	ULK1	S817	E821D	821	Missense	distal	4	no	35.891	36.351	EPSD	CCLE	29.179	Up-regulation
Other_ULK_ULK_ULK1_ST	P09467	FBP1	O75385	ULK1	T298	A292S	292	Missense	distal	-6	no	32.432	33.272	EPSD	CCLE	29.179	Up-regulation
Other_ULK_ULK_ULK1_ST	P08235	NR3C2	O75385	ULK1	S311	C308G	308	Missense	distal	-3	no	31.527	25.903	EPSD	CCLE	29.179	Loss
Other_ULK_ULK_ULK1_ST	Q8TEV9	SMCR8	O75385	ULK1	S282	Q280P	280	Missense	proximal	-2	no	32.005	30.759	EPSD	CCLE	29.179	Down-regulation
Other_ULK_ULK_ULK1_ST	Q8TEV9	SMCR8	O75385	ULK1	S465	M462I	462	Missense	distal	-3	no	41.519	29.822	EPSD	CCLE	29.179	Down-regulation
Other_ULK_ULK_ULK1_ST	Q8TEV9	SMCR8	O75385	ULK1	T666	S660N	660	Missense	distal	-6	no	40.511	39.237	EPSD;PhosphoSitePlus	CCLE	29.179	Down-regulation
Other_ULK_ULK_ULK1_ST	Q15436	SEC23A	O75385	ULK1	S588	S588P	588	Missense	central	0	yes	36.833	0.000	EPSD	CCLE	29.179	Loss
Other_ULK_ULK_ULK1_ST	Q15437	SEC23B	O75385	ULK1	T407	V410A	410	Missense	distal	3	no	34.319	34.674	EPSD	CCLE	29.179	Up-regulation
Other_ULK_ULK_ULK1_ST	Q14457	BECN1	O75385	ULK1	S64	P68S	68	Missense	distal	4	no	33.444	34.546	EPSD	CCLE	29.179	Up-regulation
Other_ULK_ULK_ULK1_ST	Q14457	BECN1	O75385	ULK1	S64	T62A	62	Missense	proximal	-2	no	33.444	33.038	EPSD	CCLE	29.179	Down-regulation
Other_ULK_ULK_ULK1_ST	Q8NFG4	FLCN	O75385	ULK1	S298	E303G	303	Missense	distal	5	no	34.105	33.971	EPSD	CCLE	29.179	Down-regulation
Other_ULK_ULK_ULK1_ST	P19367	HK1	O75385	ULK1	S88	R91Q	91	Missense	distal	3	no	32.766	35.498	EPSD	CCLE	29.179	Up-regulation
Other_ULK_ULK_ULK1_ST	P19367	HK1	O75385	ULK1	S124	I118V	118	Missense	distal	-6	no	33.000	32.238	EPSD;PhosphoSitePlus	CCLE	29.179	Down-regulation
Other_ULK_ULK_ULK1_ST	Q8TDY2	RB1CC1	O75385	ULK1	S222	C216R	216	Missense	distal	-6	no	40.072	43.254	EPSD	CCLE	29.179	Up-regulation
Other_ULK_ULK_ULK1_ST	Q8TDY2	RB1CC1	O75385	ULK1	T249	D245V	245	Missense	distal	-4	no	40.427	33.640	EPSD	CCLE	29.179	Down-regulation
Other_ULK_ULK_ULK1_ST	O15027	SEC16A	O75385	ULK1	S383	D389N	389	Missense	distal	6	no	38.725	38.605	EPSD	CCLE	29.179	Down-regulation
Other_ULK_ULK_ULK1_ST	O15027	SEC16A	O75385	ULK1	S391	P392L	392	Missense	proximal	1	no	35.029	35.043	EPSD	CCLE	29.179	Up-regulation
Other_ULK_ULK_ULK1_ST	O15027	SEC16A	O75385	ULK1	S391	D389N	389	Missense	proximal	-2	no	35.029	34.405	EPSD	CCLE	29.179	Down-regulation
Other_ULK_ULK_ULK1_ST	O15027	SEC16A	O75385	ULK1	S1045	P1043L	1043	Missense	proximal	-2	no	30.862	26.179	EPSD	CCLE	29.179	Loss
Other_ULK_ULK_ULK1_ST	O15027	SEC16A	O75385	ULK1	S1905	T1898K	1898	Missense	distal	-7	no	48.132	45.528	EPSD	CCLE	29.179	Down-regulation
Other_ULK_ULK_ULK1_ST	O00560	SDCBP	O75385	ULK1	T206	K203R	203	Missense	distal	-3	no	33.749	40.038	EPSD	CCLE	29.179	Up-regulation
Other_ULK_ULK_ULK1_ST	O00560	SDCBP	O75385	ULK1	T206	T206I	206	Missense	central	0	yes	33.749	0.000	EPSD	CCLE	29.179	Loss
Other_ULK_ULK_ULK1_ST	Q9Y4P1	ATG4B	O75385	ULK1	S316	A311T	311	Missense	distal	-5	no	41.974	43.677	PhosphoSitePlus	CCLE	29.179	Up-regulation
Other_ULK_ULK_ULK1_ST	Q8NEB9	PIK3C3	O75385	ULK1	S165	R162K	162	Missense	distal	-3	no	32.357	26.069	EPSD	CCLE	29.179	Loss
Other_ULK_ULK_ULK1_ST	Q13045	FLII	O75385	ULK1	S488	D494N	494	Missense	distal	6	no	41.275	41.155	EPSD	CCLE	29.179	Down-regulation
TK_Tec_TEC_Y	P42680	TEC	P42680	TEC	Y513	S506F	506	Missense	distal	-7	no	302.507	279.722	EPSD	CCLE	232.776	Down-regulation
Other_TLK_TLK1_ST	Q96PY6	NEK1	Q9UKI8	TLK1	S439	S436Y	436	Missense	distal	-3	no	2.260	2.381	EPSD	CCLE	2.233	Up-regulation
CMGC_CDK_CDC2_CDK1_ST	Q99638	RAD9A	P06493	CDK1	T292	Q286R	286	Missense	distal	-6	no	3.534	3.536	EPSD;PhosphoSitePlus	CCLE	3.158	Up-regulation
CMGC_CDK_CDC2_CDK1_ST	P49792	RANBP2	P06493	CDK1	T19	Q24E	24	Missense	distal	5	no	3.188	3.254	EPSD	CCLE	3.158	Up-regulation
CMGC_CDK_CDC2_CDK1_ST	P49792	RANBP2	P06493	CDK1	S394	F390V	390	Missense	distal	-4	no	3.287	3.311	EPSD	CCLE	3.158	Up-regulation
CMGC_CDK_CDC2_CDK1_ST	P49792	RANBP2	P06493	CDK1	T799	S796F	796	Missense	distal	-3	no	3.203	3.176	EPSD	CCLE	3.158	Down-regulation
CMGC_CDK_CDC2_CDK1_ST	P49792	RANBP2	P06493	CDK1	S955	A950V	950	Missense	distal	-5	no	3.102	3.242	EPSD	CCLE	3.158	Gain
CMGC_CDK_CDC2_CDK1_ST	P49792	RANBP2	P06493	CDK1	S1869	H1863Q	1863	Missense	distal	-6	no	3.179	3.173	EPSD	CCLE	3.158	Down-regulation
CMGC_CDK_CDC2_CDK1_ST	P49792	RANBP2	P06493	CDK1	T2450	I2449V	2449	Missense	proximal	-1	no	3.386	3.334	EPSD	CCLE	3.158	Down-regulation
CMGC_CDK_CDC2_CDK1_ST	P49792	RANBP2	P06493	CDK1	T2450	S2457G	2457	Missense	distal	7	no	3.386	3.414	EPSD	CCLE	3.158	Up-regulation
CMGC_CDK_CDC2_CDK1_ST	P49792	RANBP2	P06493	CDK1	S2462	S2457G	2457	Missense	distal	-5	no	3.239	3.365	EPSD	CCLE	3.158	Up-regulation
CMGC_CDK_CDC2_CDK1_ST	P49792	RANBP2	P06493	CDK1	S3207	K3200R	3200	Missense	distal	-7	no	3.646	3.722	EPSD	CCLE	3.158	Up-regulation
CMGC_CDK_CDC2_CDK1_ST	Q14980	NUMA1	P06493	CDK1	S1862	D1864N	1864	Missense	proximal	2	no	3.168	3.163	EPSD	CCLE	3.158	Down-regulation
CMGC_CDK_CDC2_CDK1_ST	Q14980	NUMA1	P06493	CDK1	T2106	A2101T	2101	Missense	distal	-5	no	3.671	3.693	EPSD;PhosphoSitePlus	CCLE	3.158	Up-regulation
CMGC_CDK_CDC2_CDK1_ST	P10636	MAPT	P06493	CDK1	T529	R526L	526	Missense	distal	-3	no	3.170	3.165	EPSD	CCLE	3.158	Down-regulation
CMGC_CDK_CDC2_CDK1_ST	P10636	MAPT	P06493	CDK1	S713	G706V	706	Missense	distal	-7	no	3.136	3.170	EPSD	CCLE	3.158	Gain
CMGC_CDK_CDC2_CDK1_ST	Q99728	BARD1	P06493	CDK1	S496	Q493H	493	Missense	distal	-3	no	3.257	3.245	EPSD	CCLE	3.158	Down-regulation
CMGC_CDK_CDC2_CDK1_ST	Q99728	BARD1	P06493	CDK1	S496	T490N	490	Missense	distal	-6	no	3.257	3.267	EPSD	CCLE	3.158	Up-regulation
CMGC_CDK_CDC2_CDK1_ST	Q9NXR1	NDE1	P06493	CDK1	S333	H329Y	329	Missense	distal	-4	no	3.202	3.173	EPSD	CCLE	3.158	Down-regulation
CMGC_CDK_CDC2_CDK1_ST	P21333	FLNA	P06493	CDK1	S1084	Q1078R	1078	Missense	distal	-6	no	3.355	3.357	EPSD;PhosphoSitePlus	CCLE	3.158	Up-regulation
CMGC_CDK_CDC2_CDK1_ST	P19338	NCL	P06493	CDK1	S67	V72I	72	Missense	distal	5	no	3.190	3.204	EPSD	CCLE	3.158	Up-regulation
CMGC_CDK_CDC2_CDK1_ST	O95139	NDUFB6	P06493	CDK1	S29	P30S	30	Missense	proximal	1	no	3.676	0.492	PhosphoSitePlus;EPSD	CCLE	3.158	Loss
CMGC_CDK_CDC2_CDK1_ST	Q9HCH0	NCKAP5L	P06493	CDK1	S818	P819F	819	Missense	proximal	1	no	3.462	-0.424	EPSD	CCLE	3.158	Loss
CMGC_CDK_CDC2_CDK1_ST	P18031	PTPN1	P06493	CDK1	S50	P51S	51	Missense	proximal	1	no	3.524	0.340	EPSD	CCLE	3.158	Loss
CMGC_CDK_CDC2_CDK1_ST	Q9H8V3	ECT2	P06493	CDK1	S397	V396M	396	Missense	proximal	-1	no	3.412	3.354	EPSD	CCLE	3.158	Down-regulation
CMGC_CDK_CDC2_CDK1_ST	Q9H8V3	ECT2	P06493	CDK1	T444	P445A	445	Missense	proximal	1	no	3.438	2.549	EPSD;PhosphoSitePlus	CCLE	3.158	Loss
CMGC_CDK_CDC2_CDK1_ST	O14757	CHEK1	P06493	CDK1	T362	Q358R	358	Missense	distal	-4	no	3.499	3.480	EPSD	CCLE	3.158	Down-regulation
CMGC_CDK_CDC2_CDK1_ST	P11171	EPB41	P06493	CDK1	S712	I719T	719	Missense	distal	7	no	3.336	3.313	EPSD	CCLE	3.158	Down-regulation
CMGC_CDK_CDC2_CDK1_ST	Q92974	ARHGEF2	P06493	CDK1	S648	L646P	646	Missense	proximal	-2	no	3.293	3.120	EPSD	CCLE	3.158	Loss
CMGC_CDK_CDC2_CDK1_ST	Q92974	ARHGEF2	P06493	CDK1	S648	R642S	642	Missense	distal	-6	no	3.293	3.286	EPSD	CCLE	3.158	Down-regulation
CMGC_CDK_CDC2_CDK1_ST	Q92974	ARHGEF2	P06493	CDK1	S932	G931E	931	Missense	proximal	-1	no	3.444	3.317	EPSD	CCLE	3.158	Down-regulation
CMGC_CDK_CDC2_CDK1_ST	Q14202	ZMYM3	P06493	CDK1	T62	A64S	64	Missense	proximal	2	no	3.497	3.503	EPSD	CCLE	3.158	Up-regulation
CMGC_CDK_CDC2_CDK1_ST	Q14202	ZMYM3	P06493	CDK1	S774	P775S	775	Missense	proximal	1	no	3.322	0.137	EPSD	CCLE	3.158	Loss
CMGC_CDK_CDC2_CDK1_ST	Q9UQ35	SRRM2	P06493	CDK1	S1014	P1015S	1015	Missense	proximal	1	no	4.251	1.067	EPSD	CCLE	3.158	Loss
CMGC_CDK_CDC2_CDK1_ST	Q9UQ35	SRRM2	P06493	CDK1	T2738	H2732Q	2732	Missense	distal	-6	no	3.235	3.229	EPSD	CCLE	3.158	Down-regulation
CMGC_CDK_CDC2_CDK1_ST	Q32P44	EML3	P06493	CDK1	T881	P886F	886	Missense	distal	5	no	3.120	3.259	PhosphoSitePlus	CCLE	3.158	Gain
CMGC_CDK_CDC2_CDK1_ST	Q32P44	EML3	P06493	CDK1	S889	P886F	886	Missense	distal	-3	no	3.661	3.634	EPSD	CCLE	3.158	Down-regulation
CMGC_CDK_CDC2_CDK1_ST	Q9H1A4	ANAPC1	P06493	CDK1	S377	I383L	383	Missense	distal	6	no	3.324	3.311	EPSD;PhosphoSitePlus	CCLE	3.158	Down-regulation
CMGC_CDK_CDC2_CDK1_ST	Q8IZD2	KMT2E	P06493	CDK1	S837	I831S	831	Missense	distal	-6	no	3.275	3.252	EPSD	CCLE	3.158	Down-regulation
CMGC_CDK_CDC2_CDK1_ST	Q8IZD2	KMT2E	P06493	CDK1	T904	T901S	901	Missense	distal	-3	no	3.351	3.346	EPSD	CCLE	3.158	Down-regulation
CMGC_CDK_CDC2_CDK1_ST	Q8IZD2	KMT2E	P06493	CDK1	T1147	N1145S	1145	Missense	proximal	-2	no	3.525	3.496	EPSD	CCLE	3.158	Down-regulation
CMGC_CDK_CDC2_CDK1_ST	Q8IZD2	KMT2E	P06493	CDK1	S1466	P1459S	1459	Missense	distal	-7	no	3.210	3.250	EPSD	CCLE	3.158	Up-regulation
CMGC_CDK_CDC2_CDK1_ST	Q01581	HMGCS1	P06493	CDK1	T471	R469H	469	Missense	proximal	-2	no	3.222	3.176	EPSD	CCLE	3.158	Down-regulation
CMGC_CDK_CDC2_CDK1_ST	Q96GX5	MASTL	P06493	CDK1	T718	Y720C	720	Missense	proximal	2	no	3.397	3.395	EPSD	CCLE	3.158	Down-regulation
CMGC_CDK_CDC2_CDK1_ST	Q96GX5	MASTL	P06493	CDK1	T718	T722N	722	Missense	distal	4	no	3.397	3.371	EPSD	CCLE	3.158	Down-regulation
CMGC_CDK_CDC2_CDK1_ST	Q96GX5	MASTL	P06493	CDK1	T722	Y720C	720	Missense	proximal	-2	no	3.459	3.425	EPSD	CCLE	3.158	Down-regulation
CMGC_CDK_CDC2_CDK1_ST	Q96GX5	MASTL	P06493	CDK1	T722	T722N	722	Missense	central	0	yes	3.459	0.000	EPSD	CCLE	3.158	Loss
CMGC_CDK_CDC2_CDK1_ST	Q8WUF5	PPP1R13L	P06493	CDK1	T95	T95N	95	Missense	central	0	yes	3.180	0.000	EPSD	CCLE	3.158	Loss
CMGC_CDK_CDC2_CDK1_ST	Q8WUF5	PPP1R13L	P06493	CDK1	T95	T95P	95	Missense	central	0	yes	3.180	0.000	EPSD	CCLE	3.158	Loss
CMGC_CDK_CDC2_CDK1_ST	Q8WUF5	PPP1R13L	P06493	CDK1	T95	A88T	88	Missense	distal	-7	no	3.180	3.174	EPSD	CCLE	3.158	Down-regulation
CMGC_CDK_CDC2_CDK1_ST	Q8WUF5	PPP1R13L	P06493	CDK1	S158	P161T	161	Missense	distal	3	no	3.341	3.356	EPSD	CCLE	3.158	Up-regulation
CMGC_CDK_CDC2_CDK1_ST	Q8WUF5	PPP1R13L	P06493	CDK1	S187	S183P	183	Missense	distal	-4	no	3.223	3.172	EPSD	CCLE	3.158	Down-regulation
CMGC_CDK_CDC2_CDK1_ST	Q8WUF5	PPP1R13L	P06493	CDK1	S616	R621L	621	Missense	distal	5	no	3.554	3.777	EPSD	CCLE	3.158	Up-regulation
CMGC_CDK_CDC2_CDK1_ST	Q8WUF5	PPP1R13L	P06493	CDK1	S616	R621H	621	Missense	distal	5	no	3.554	3.619	EPSD	CCLE	3.158	Up-regulation
CMGC_CDK_CDC2_CDK1_ST	Q8WUF5	PPP1R13L	P06493	CDK1	S616	A614V	614	Missense	proximal	-2	no	3.554	3.719	EPSD	CCLE	3.158	Up-regulation
CMGC_CDK_CDC2_CDK1_ST	Q12778	FOXO1	P06493	CDK1	S329	S325T	325	Missense	distal	-4	no	3.261	3.270	EPSD	CCLE	3.158	Up-regulation
CMGC_CDK_CDC2_CDK1_ST	Q12778	FOXO1	P06493	CDK1	S432	M431V	431	Missense	proximal	-1	no	3.415	3.472	EPSD	CCLE	3.158	Up-regulation
CMGC_CDK_CDC2_CDK1_ST	Q12888	TP53BP1	P06493	CDK1	S265	M262R	262	Missense	distal	-3	no	3.373	3.360	EPSD	CCLE	3.158	Down-regulation
CMGC_CDK_CDC2_CDK1_ST	Q12888	TP53BP1	P06493	CDK1	S1362	S1368R	1368	Missense	distal	6	no	3.878	3.884	EPSD	CCLE	3.158	Up-regulation
CMGC_CDK_CDC2_CDK1_ST	Q12888	TP53BP1	P06493	CDK1	S1362	V1367I	1367	Missense	distal	5	no	3.878	3.892	EPSD	CCLE	3.158	Up-regulation
CMGC_CDK_CDC2_CDK1_ST	Q12888	TP53BP1	P06493	CDK1	T1638	V1633I	1633	Missense	distal	-5	no	3.152	3.165	EPSD	CCLE	3.158	Gain
CMGC_CDK_CDC2_CDK1_ST	Q09666	AHNAK	P06493	CDK1	S93	E95D	95	Missense	proximal	2	no	3.165	3.166	EPSD	CCLE	3.158	Up-regulation
CMGC_CDK_CDC2_CDK1_ST	Q09666	AHNAK	P06493	CDK1	T324	S317L	317	Missense	distal	-7	no	3.806	3.606	EPSD	CCLE	3.158	Down-regulation
CMGC_CDK_CDC2_CDK1_ST	Q09666	AHNAK	P06493	CDK1	T1192	E1187D	1187	Missense	distal	-5	no	3.414	3.405	EPSD	CCLE	3.158	Down-regulation
CMGC_CDK_CDC2_CDK1_ST	Q09666	AHNAK	P06493	CDK1	T2832	P2838L	2838	Missense	distal	6	no	3.419	3.363	EPSD	CCLE	3.158	Down-regulation
CMGC_CDK_CDC2_CDK1_ST	Q09666	AHNAK	P06493	CDK1	T4564	V4560L	4560	Missense	distal	-4	no	3.625	3.552	EPSD	CCLE	3.158	Down-regulation
CMGC_CDK_CDC2_CDK1_ST	Q09666	AHNAK	P06493	CDK1	T5184	A5191T	5191	Missense	distal	7	no	3.571	3.585	EPSD	CCLE	3.158	Up-regulation
CMGC_CDK_CDC2_CDK1_ST	Q96IF1	AJUBA	P06493	CDK1	S119	R121H	121	Missense	proximal	2	no	3.371	3.376	EPSD;PhosphoSitePlus	CCLE	3.158	Up-regulation
CMGC_CDK_CDC2_CDK1_ST	P55211	CASP9	P06493	CDK1	T125	R122K	122	Missense	distal	-3	no	3.655	3.643	PhosphoSitePlus	CCLE	3.158	Down-regulation
CMGC_CDK_CDC2_CDK1_ST	Q13042	CDC16	P06493	CDK1	T581	A575V	575	Missense	distal	-6	no	3.329	3.350	EPSD;PhosphoSitePlus	CCLE	3.158	Up-regulation
CMGC_CDK_CDC2_CDK1_ST	Q13042	CDC16	P06493	CDK1	T581	E577G	577	Missense	distal	-4	no	3.329	3.251	EPSD;PhosphoSitePlus	CCLE	3.158	Down-regulation
CMGC_CDK_CDC2_CDK1_ST	Q92574	TSC1	P06493	CDK1	S644	G639V	639	Missense	distal	-5	no	3.512	3.503	EPSD	CCLE	3.158	Down-regulation
CMGC_CDK_CDC2_CDK1_ST	P47736	RAP1GAP	P06493	CDK1	S74	E68K	68	Missense	distal	-6	no	3.462	3.463	EPSD	CCLE	3.158	Up-regulation
CMGC_CDK_CDC2_CDK1_ST	Q99661	KIF2C	P06493	CDK1	S589	S592N	592	Missense	distal	3	no	3.234	3.239	EPSD	CCLE	3.158	Up-regulation
CMGC_CDK_CDC2_CDK1_ST	Q92993	KAT5	P06493	CDK1	S90	L83I	83	Missense	distal	-7	no	4.120	4.168	EPSD;PhosphoSitePlus	CCLE	3.158	Up-regulation
CMGC_CDK_CDC2_CDK1_ST	Q92993	KAT5	P06493	CDK1	S90	P88S	88	Missense	proximal	-2	no	4.120	4.246	EPSD;PhosphoSitePlus	CCLE	3.158	Up-regulation
CMGC_CDK_CDC2_CDK1_ST	Q92993	KAT5	P06493	CDK1	S90	P88F	88	Missense	proximal	-2	no	4.120	4.314	EPSD;PhosphoSitePlus	CCLE	3.158	Up-regulation
CMGC_CDK_CDC2_CDK1_ST	Q92993	KAT5	P06493	CDK1	S90	P88L	88	Missense	proximal	-2	no	4.120	4.293	EPSD;PhosphoSitePlus	CCLE	3.158	Up-regulation
CMGC_CDK_CDC2_CDK1_ST	Q92993	KAT5	P06493	CDK1	S90	E92Q	92	Missense	proximal	2	no	4.120	4.113	EPSD;PhosphoSitePlus	CCLE	3.158	Down-regulation
CMGC_CDK_CDC2_CDK1_ST	Q01167	FOXK2	P06493	CDK1	S213	S212C	212	Missense	proximal	-1	no	3.683	3.800	EPSD	CCLE	3.158	Up-regulation
CMGC_CDK_CDC2_CDK1_ST	Q01167	FOXK2	P06493	CDK1	S213	A217V	217	Missense	distal	4	no	3.683	3.547	EPSD	CCLE	3.158	Down-regulation
CMGC_CDK_CDC2_CDK1_ST	O00418	EEF2K	P06493	CDK1	S359	S359C	359	Missense	central	0	yes	3.244	0.000	PhosphoSitePlus	CCLE	3.158	Loss
CMGC_CDK_CDC2_CDK1_ST	O00418	EEF2K	P06493	CDK1	T401	S404N	404	Missense	distal	3	no	3.389	3.394	EPSD	CCLE	3.158	Up-regulation
CMGC_CDK_CDC2_CDK1_ST	Q9BXS6	NUSAP1	P06493	CDK1	S135	K132R	132	Missense	distal	-3	no	3.211	3.223	EPSD	CCLE	3.158	Up-regulation
CMGC_CDK_CDC2_CDK1_ST	O00443	PIK3C2A	P06493	CDK1	T120	S124N	124	Missense	distal	4	no	3.322	3.304	EPSD	CCLE	3.158	Down-regulation
CMGC_CDK_CDC2_CDK1_ST	O00443	PIK3C2A	P06493	CDK1	S124	S124N	124	Missense	central	0	yes	3.162	0.000	EPSD	CCLE	3.158	Loss
CMGC_CDK_CDC2_CDK1_ST	Q9BW19	KIFC1	P06493	CDK1	S6	D2N	2	Missense	distal	-4	no	3.475	3.460	EPSD;PhosphoSitePlus	CCLE	3.158	Down-regulation
CMGC_CDK_CDC2_CDK1_ST	P20700	LMNB1	P06493	CDK1	S23	R29W	29	Missense	distal	6	no	3.209	3.171	PhosphoSitePlus;EPSD	CCLE	3.158	Down-regulation
CMGC_CDK_CDC2_CDK1_ST	Q01094	E2F1	P06493	CDK1	T311	G309R	309	Missense	proximal	-2	no	3.452	3.430	EPSD	CCLE	3.158	Down-regulation
CMGC_CDK_CDC2_CDK1_ST	Q01094	E2F1	P06493	CDK1	S375	R373S	373	Missense	proximal	-2	no	3.327	3.261	EPSD	CCLE	3.158	Down-regulation
CMGC_CDK_CDC2_CDK1_ST	Q01094	E2F1	P06493	CDK1	S403	L402F	402	Missense	proximal	-1	no	3.534	3.485	EPSD	CCLE	3.158	Down-regulation
CMGC_CDK_CDC2_CDK1_ST	Q8IWB6	TEX14	P06493	CDK1	S168	Y174C	174	Missense	distal	6	no	3.816	3.823	EPSD	CCLE	3.158	Up-regulation
CMGC_CDK_CDC2_CDK1_ST	Q8IWB6	TEX14	P06493	CDK1	T1277	E1276K	1276	Missense	proximal	-1	no	3.674	3.712	EPSD	CCLE	3.158	Up-regulation
CMGC_CDK_CDC2_CDK1_ST	P98170	XIAP	P06493	CDK1	S40	A34G	34	Missense	distal	-6	no	3.582	3.607	PhosphoSitePlus	CCLE	3.158	Up-regulation
CMGC_CDK_CDC2_CDK1_ST	Q08050	FOXM1	P06493	CDK1	T510	K514N	514	Missense	distal	4	no	3.316	3.312	EPSD	CCLE	3.158	Down-regulation
CMGC_CDK_CDC2_CDK1_ST	P02545	LMNA	P06493	CDK1	S390	R388H	388	Missense	proximal	-2	no	3.258	3.212	EPSD;PhosphoSitePlus	CCLE	3.158	Down-regulation
CMGC_CDK_CDC2_CDK1_ST	P02545	LMNA	P06493	CDK1	S568	H569P	569	Missense	proximal	1	no	0.685	3.369	EPSD	CCLE	3.158	Gain
CMGC_CDK_CDC2_CDK1_ST	P02545	LMNA	P06493	CDK1	S657	P658S	658	Missense	proximal	1	no	3.356	0.171	EPSD	CCLE	3.158	Loss
CMGC_CDK_CDC2_CDK1_ST	P0C1Z6	TFPT	P06493	CDK1	S249	Y244C	244	Missense	distal	-5	no	3.222	3.231	EPSD	CCLE	3.158	Up-regulation
CMGC_CDK_CDC2_CDK1_ST	Q14674	ESPL1	P06493	CDK1	T1210	P1216Q	1216	Missense	distal	6	no	3.327	3.323	EPSD	CCLE	3.158	Down-regulation
CMGC_CDK_CDC2_CDK1_ST	P54132	BLM	P06493	CDK1	S714	V721T	721	Missense	distal	7	no	3.348	3.328	PhosphoSitePlus;EPSD	CCLE	3.158	Down-regulation
CMGC_CDK_CDC2_CDK1_ST	P39748	FEN1	P06493	CDK1	S187	M191I	191	Missense	distal	4	no	3.240	3.178	PhosphoSitePlus	CCLE	3.158	Down-regulation
CMGC_CDK_CDC2_CDK1_ST	P68400	CSNK2A1	P06493	CDK1	S362	G369S	369	Missense	distal	7	no	3.331	3.304	EPSD;PhosphoSitePlus	CCLE	3.158	Down-regulation
CMGC_CDK_CDC2_CDK1_ST	P30305	CDC25B	P06493	CDK1	S15	A13D	13	Missense	proximal	-2	no	3.231	3.369	EPSD	CCLE	3.158	Up-regulation
CMGC_CDK_CDC2_CDK1_ST	P30305	CDC25B	P06493	CDK1	S416	L412H	412	Missense	distal	-4	no	3.703	3.827	EPSD	CCLE	3.158	Up-regulation
CMGC_CDK_CDC2_CDK1_ST	O00571	DDX3X	P06493	CDK1	S492	K491R	491	Missense	proximal	-1	no	3.318	3.248	EPSD	CCLE	3.158	Down-regulation
CMGC_CDK_CDC2_CDK1_ST	Q9UGP4	LIMD1	P06493	CDK1	S424	S421N	421	Missense	distal	-3	no	3.218	3.201	EPSD;PhosphoSitePlus	CCLE	3.158	Down-regulation
CMGC_CDK_CDC2_CDK1_ST	P26368	U2AF2	P06493	CDK1	S346	P347L	347	Missense	proximal	1	no	3.817	0.131	EPSD	CCLE	3.158	Loss
CMGC_CDK_CDC2_CDK1_ST	P27816	MAP4	P06493	CDK1	S14	P13L	13	Missense	proximal	-1	no	3.613	3.764	EPSD	CCLE	3.158	Up-regulation
CMGC_CDK_CDC2_CDK1_ST	Q8IX90	SKA3	P06493	CDK1	T358	T365N	365	Missense	distal	7	no	3.753	3.757	PhosphoSitePlus;EPSD	CCLE	3.158	Up-regulation
CMGC_CDK_CDC2_CDK1_ST	Q12959	DLG1	P06493	CDK1	S448	V450G	450	Missense	proximal	2	no	3.218	3.225	EPSD	CCLE	3.158	Up-regulation
CMGC_CDK_CDC2_CDK1_ST	Q12959	DLG1	P06493	CDK1	T630	Q628H	628	Missense	proximal	-2	no	3.342	3.350	EPSD	CCLE	3.158	Up-regulation
CMGC_CDK_CDC2_CDK1_ST	Q9UPU5	USP24	P06493	CDK1	S1943	K1946E	1946	Missense	distal	3	no	3.195	3.091	EPSD	CCLE	3.158	Loss
CMGC_CDK_CDC2_CDK1_ST	Q9UPU5	USP24	P06493	CDK1	S1943	G1939V	1939	Missense	distal	-4	no	3.195	3.212	EPSD	CCLE	3.158	Up-regulation
CMGC_CDK_CDC2_CDK1_ST	P24928	POLR2A	P06493	CDK1	S1948	S1941F	1941	Missense	distal	-7	no	3.341	3.194	EPSD	CCLE	3.158	Down-regulation
CMGC_CDK_CDC2_CDK1_ST	P24928	POLR2A	P06493	CDK1	S1948	S1944Y	1944	Missense	distal	-4	no	3.341	3.242	EPSD	CCLE	3.158	Down-regulation
CMGC_CDK_CDC2_CDK1_ST	P24928	POLR2A	P06493	CDK1	S1948	P1952A	1952	Missense	distal	4	no	3.341	3.397	EPSD	CCLE	3.158	Up-regulation
CMGC_CDK_CDC2_CDK1_ST	Q53EZ4	CEP55	P06493	CDK1	S428	A423T	423	Missense	distal	-5	no	3.623	3.644	EPSD;PhosphoSitePlus	CCLE	3.158	Up-regulation
CMGC_CDK_CDC2_CDK1_ST	Q8NHV4	NEDD1	P06493	CDK1	S411	G407S	407	Missense	distal	-4	no	3.989	4.127	EPSD;PhosphoSitePlus	CCLE	3.158	Up-regulation
CMGC_CDK_CDC2_CDK1_ST	Q8NHV4	NEDD1	P06493	CDK1	S411	S411L	411	Missense	central	0	yes	3.989	0.000	EPSD;PhosphoSitePlus	CCLE	3.158	Loss
CMGC_CDK_CDC2_CDK1_ST	Q9BTA9	WAC	P06493	CDK1	S351	Q358E	358	Missense	distal	7	no	3.324	3.335	EPSD	CCLE	3.158	Up-regulation
CMGC_CDK_CDC2_CDK1_ST	O75154	RAB11FIP3	P06493	CDK1	T562	R559Q	559	Missense	distal	-3	no	3.161	3.184	EPSD	CCLE	3.158	Up-regulation
CMGC_CDK_CDC2_CDK1_ST	Q8NCD3	HJURP	P06493	CDK1	T380	P381S	381	Missense	proximal	1	no	3.423	0.239	EPSD	CCLE	3.158	Loss
CMGC_CDK_CDC2_CDK1_ST	P46013	MKI67	P06493	CDK1	S1071	P1072L	1072	Missense	proximal	1	no	3.302	-0.384	EPSD	CCLE	3.158	Loss
CMGC_CDK_CDC2_CDK1_ST	P46013	MKI67	P06493	CDK1	T1540	S1533L	1533	Missense	distal	-7	no	4.189	3.988	EPSD	CCLE	3.158	Down-regulation
CMGC_CDK_CDC2_CDK1_ST	P46013	MKI67	P06493	CDK1	T1923	E1926Q	1926	Missense	distal	3	no	3.161	3.235	EPSD	CCLE	3.158	Up-regulation
CMGC_CDK_CDC2_CDK1_ST	Q99708	RBBP8	P06493	CDK1	S568	P563A	563	Missense	distal	-5	no	3.390	3.344	EPSD	CCLE	3.158	Down-regulation
CMGC_CDK_CDC2_CDK1_ST	O00512	BCL9	P06493	CDK1	S62	P63A	63	Missense	proximal	1	no	3.412	2.523	EPSD	CCLE	3.158	Loss
CMGC_CDK_CDC2_CDK1_ST	O00512	BCL9	P06493	CDK1	S441	G434A	434	Missense	distal	-7	no	3.178	3.364	EPSD	CCLE	3.158	Up-regulation
CMGC_CDK_CDC2_CDK1_ST	Q9H410	DSN1	P06493	CDK1	S58	S57F	57	Missense	proximal	-1	no	3.055	3.208	EPSD	CCLE	3.158	Gain
CMGC_CDK_CDC2_CDK1_ST	P29692	EEF1D	P06493	CDK1	S133	R136P	136	Missense	distal	3	no	3.494	3.373	PhosphoSitePlus	CCLE	3.158	Down-regulation
CMGC_CDK_CDC2_CDK1_ST	P29692	EEF1D	P06493	CDK1	S133	R136S	136	Missense	distal	3	no	3.494	3.423	PhosphoSitePlus	CCLE	3.158	Down-regulation
CMGC_CDK_CDC2_CDK1_ST	P29692	EEF1D	P06493	CDK1	S133	A126V	126	Missense	distal	-7	no	3.494	3.342	PhosphoSitePlus	CCLE	3.158	Down-regulation
CMGC_CDK_CDC2_CDK1_ST	O14773	TPP1	P06493	CDK1	T478	G483W	483	Missense	distal	5	no	3.315	3.235	EPSD	CCLE	3.158	Down-regulation
CMGC_CDK_CDC2_CDK1_ST	P06400	RB1	P06493	CDK1	S612	P609H	609	Missense	distal	-3	no	3.596	3.580	EPSD	CCLE	3.158	Down-regulation
CMGC_CDK_CDC2_CDK1_ST	Q69YH5	CDCA2	P06493	CDK1	S98	I105T	105	Missense	distal	7	no	3.244	3.221	EPSD	CCLE	3.158	Down-regulation
CMGC_CDK_CDC2_CDK1_ST	Q69YH5	CDCA2	P06493	CDK1	S120	P121H	121	Missense	proximal	1	no	3.204	0.520	EPSD	CCLE	3.158	Loss
CMGC_CDK_CDC2_CDK1_ST	Q69YH5	CDCA2	P06493	CDK1	T321	C315Y	315	Missense	distal	-6	no	3.165	3.166	EPSD	CCLE	3.158	Up-regulation
CMGC_CDK_CDC2_CDK1_ST	Q69YH5	CDCA2	P06493	CDK1	S591	P592L	592	Missense	proximal	1	no	3.716	0.029	EPSD	CCLE	3.158	Loss
CMGC_CDK_CDC2_CDK1_ST	Q69YH5	CDCA2	P06493	CDK1	T628	E625Q	625	Missense	distal	-3	no	3.379	3.402	EPSD	CCLE	3.158	Up-regulation
CMGC_CDK_CDC2_CDK1_ST	Q69YH5	CDCA2	P06493	CDK1	T628	R635I	635	Missense	distal	7	no	3.379	3.397	EPSD	CCLE	3.158	Up-regulation
CMGC_CDK_CDC2_CDK1_ST	Q8TAP9	MPLKIP	P06493	CDK1	S40	G44R	44	Missense	distal	4	no	3.042	3.168	EPSD	CCLE	3.158	Gain
CMGC_CDK_CDC2_CDK1_ST	Q6PGQ7	BORA	P06493	CDK1	S183	P184H	184	Missense	proximal	1	no	3.308	0.624	EPSD	CCLE	3.158	Loss
CMGC_CDK_CDC2_CDK1_ST	P13639	EEF2	P06493	CDK1	S360	P361H	361	Missense	proximal	1	no	3.418	0.734	EPSD	CCLE	3.158	Loss
CMGC_CDK_CDC2_CDK1_ST	P13639	EEF2	P06493	CDK1	T735	R739H	739	Missense	distal	4	no	3.177	3.135	EPSD	CCLE	3.158	Loss
CMGC_CDK_CDC2_CDK1_ST	Q9UJX2	CDC23	P06493	CDK1	T596	T596M	596	Missense	central	0	yes	3.231	0.000	EPSD	CCLE	3.158	Loss
CMGC_CDK_CDC2_CDK1_ST	Q13535	ATR	P06493	CDK1	S428	N423D	423	Missense	distal	-5	no	3.175	3.172	PhosphoSitePlus	CCLE	3.158	Down-regulation
CMGC_CDK_CDC2_CDK1_ST	Q9ULW0	TPX2	P06493	CDK1	T113	R120K	120	Missense	distal	7	no	3.322	3.324	EPSD	CCLE	3.158	Up-regulation
CMGC_CDK_CDC2_CDK1_ST	Q9ULW0	TPX2	P06493	CDK1	S293	S293F	293	Missense	central	0	yes	3.213	0.000	EPSD	CCLE	3.158	Loss
CMGC_CDK_CDC2_CDK1_ST	P38398	BRCA1	P06493	CDK1	T967	L973F	973	Missense	distal	6	no	3.517	3.530	EPSD	CCLE	3.158	Up-regulation
CMGC_CDK_CDC2_CDK1_ST	P38398	BRCA1	P06493	CDK1	S1613	E1609D	1609	Missense	distal	-4	no	3.222	3.224	EPSD	CCLE	3.158	Up-regulation
CMGC_CDK_CDC2_CDK1_ST	P49916	LIG3	P06493	CDK1	S242	G237E	237	Missense	distal	-5	no	3.449	3.377	EPSD	CCLE	3.158	Down-regulation
CMGC_CDK_CDC2_CDK1_ST	P49916	LIG3	P06493	CDK1	S242	S242R	242	Missense	central	0	yes	3.449	0.000	EPSD	CCLE	3.158	Loss
CMGC_CDK_CDC2_CDK1_ST	Q14203	DCTN1	P06493	CDK1	S203	P199L	199	Missense	distal	-4	no	3.392	3.248	EPSD	CCLE	3.158	Down-regulation
CMGC_CDK_CDC2_CDK1_ST	O14715	RGPD8	P06493	CDK1	T1528	T1529P	1529	Missense	proximal	1	no	0.804	3.238	EPSD	CCLE	3.158	Gain
CMGC_CDK_CDC2_CDK1_ST	O95239	KIF4A	P06493	CDK1	S1225	I1227V	1227	Missense	proximal	2	no	3.430	3.425	EPSD	CCLE	3.158	Down-regulation
CMGC_CDK_CDC2_CDK1_ST	P36956	SREBF1	P06493	CDK1	S63	P69T	69	Missense	distal	6	no	3.357	3.366	EPSD	CCLE	3.158	Up-regulation
CMGC_CDK_CDC2_CDK1_ST	P36956	SREBF1	P06493	CDK1	S63	A62V	62	Missense	proximal	-1	no	3.357	3.557	EPSD	CCLE	3.158	Up-regulation
CMGC_CDK_CDC2_CDK1_ST	P36956	SREBF1	P06493	CDK1	T105	K108Q	108	Missense	distal	3	no	3.336	3.305	EPSD	CCLE	3.158	Down-regulation
CMGC_CDK_CDC2_CDK1_ST	P05067	APP	P06493	CDK1	T743	D739V	739	Missense	distal	-4	no	3.318	3.255	PhosphoSitePlus	CCLE	3.158	Down-regulation
CMGC_CDK_CDC2_CDK1_ST	Q13009	TIAM1	P06493	CDK1	S1018	P1021H	1021	Missense	distal	3	no	3.433	3.461	EPSD	CCLE	3.158	Up-regulation
CMGC_CDK_CDC2_CDK1_ST	Q13009	TIAM1	P06493	CDK1	S1018	P1021S	1021	Missense	distal	3	no	3.433	3.483	EPSD	CCLE	3.158	Up-regulation
CMGC_CDK_CDC2_CDK1_ST	Q13009	TIAM1	P06493	CDK1	S1018	M1012L	1012	Missense	distal	-6	no	3.433	3.451	EPSD	CCLE	3.158	Up-regulation
CMGC_CDK_CDC2_CDK1_ST	Q9Y3Z3	SAMHD1	P06493	CDK1	S33	S33F	33	Missense	central	0	yes	3.315	0.000	EPSD	CCLE	3.158	Loss
CMGC_CDK_CDC2_CDK1_ST	O00267	SUPT5H	P06493	CDK1	T854	G853E	853	Missense	proximal	-1	no	3.248	3.121	EPSD	CCLE	3.158	Loss
CMGC_CDK_CDC2_CDK1_ST	O00267	SUPT5H	P06493	CDK1	T854	T854P	854	Missense	central	0	yes	3.248	0.000	EPSD	CCLE	3.158	Loss
CMGC_CDK_CDC2_CDK1_ST	Q96KB5	PBK	P06493	CDK1	T24	K17R	17	Missense	distal	-7	no	3.161	3.237	EPSD	CCLE	3.158	Up-regulation
CMGC_CDK_CDC2_CDK1_ST	P10415	BCL2	P06493	CDK1	T74	Q73H	73	Missense	proximal	-1	no	3.764	3.799	EPSD	CCLE	3.158	Up-regulation
CMGC_CDK_CDC2_CDK1_ST	P54578	USP14	P06493	CDK1	T459	R465Q	465	Missense	distal	6	no	3.815	3.798	EPSD	CCLE	3.158	Down-regulation
CMGC_CDK_CDC2_CDK1_ST	P23769	GATA2	P06493	CDK1	S73	P74A	74	Missense	proximal	1	no	3.602	2.713	EPSD	CCLE	3.158	Loss
CMGC_CDK_CDC2_CDK1_ST	Q8IX03	WWC1	P06493	CDK1	S358	P359L	359	Missense	proximal	1	no	3.522	-0.164	EPSD	CCLE	3.158	Loss
CMGC_CDK_CDC2_CDK1_ST	O15530	PDPK1	P06493	CDK1	T37	T31A	31	Missense	distal	-6	no	3.420	3.419	EPSD	CCLE	3.158	Down-regulation
CMGC_CDK_CDC2_CDK1_ST	O15530	PDPK1	P06493	CDK1	T37	P42T	42	Missense	distal	5	no	3.420	3.398	EPSD	CCLE	3.158	Down-regulation
CMGC_CDK_CDC2_CDK1_ST	Q96T23	RSF1	P06493	CDK1	S629	N633S	633	Missense	distal	4	no	3.551	3.569	EPSD	CCLE	3.158	Up-regulation
CMGC_CDK_CDC2_CDK1_ST	Q96T23	RSF1	P06493	CDK1	S778	R773C	773	Missense	distal	-5	no	3.163	3.195	EPSD	CCLE	3.158	Up-regulation
CMGC_CDK_CDC2_CDK1_ST	Q96C36	PYCR2	P06493	CDK1	S233	N230T	230	Missense	distal	-3	no	3.541	3.562	EPSD	CCLE	3.158	Up-regulation
CMGC_CDK_CDC2_CDK1_ST	Q2NKX8	ERCC6L	P06493	CDK1	S755	L758F	758	Missense	distal	3	no	3.155	3.207	EPSD	CCLE	3.158	Gain
CMGC_CDK_CDC2_CDK1_ST	P18858	LIG1	P06493	CDK1	T183	D179N	179	Missense	distal	-4	no	3.364	3.350	EPSD	CCLE	3.158	Down-regulation
CMGC_CDK_CDC2_CDK1_ST	P18858	LIG1	P06493	CDK1	S323	V330I	330	Missense	distal	7	no	3.431	3.433	EPSD	CCLE	3.158	Up-regulation
CMGC_CDK_CDC2_CDK1_ST	Q9Y4H2	IRS2	P06493	CDK1	S3	G8W	8	Missense	distal	5	no	3.270	3.191	EPSD	CCLE	3.158	Down-regulation
CMGC_CDK_CDC2_CDK1_ST	Q9Y4H2	IRS2	P06493	CDK1	T527	G533S	533	Missense	distal	6	no	3.374	3.428	EPSD	CCLE	3.158	Up-regulation
CMGC_CDK_CDC2_CDK1_ST	Q9Y4H2	IRS2	P06493	CDK1	T527	I524V	524	Missense	distal	-3	no	3.374	3.395	EPSD	CCLE	3.158	Up-regulation
CMGC_CDK_CDC2_CDK1_ST	Q9Y4H2	IRS2	P06493	CDK1	T657	D651N	651	Missense	distal	-6	no	3.213	3.212	EPSD	CCLE	3.158	Down-regulation
CMGC_CDK_CDC2_CDK1_ST	Q9Y4H2	IRS2	P06493	CDK1	S736	M743I	743	Missense	distal	7	no	3.437	3.452	EPSD	CCLE	3.158	Up-regulation
CMGC_CDK_CDC2_CDK1_ST	Q9Y4H2	IRS2	P06493	CDK1	S736	M743V	743	Missense	distal	7	no	3.437	3.449	EPSD	CCLE	3.158	Up-regulation
CMGC_CDK_CDC2_CDK1_ST	Q9Y4H2	IRS2	P06493	CDK1	T1082	A1088T	1088	Missense	distal	6	no	3.332	3.323	EPSD	CCLE	3.158	Down-regulation
CMGC_CDK_CDC2_CDK1_ST	O60285	NUAK1	P06493	CDK1	S455	M462I	462	Missense	distal	7	no	3.500	3.514	EPSD	CCLE	3.158	Up-regulation
CMGC_CDK_CDC2_CDK1_ST	O60285	NUAK1	P06493	CDK1	S542	P546L	546	Missense	distal	4	no	3.304	3.182	EPSD	CCLE	3.158	Down-regulation
CMGC_CDK_CDC2_CDK1_ST	Q9H9S0	NANOG	P06493	CDK1	S65	M58V	58	Missense	distal	-7	no	3.327	3.270	EPSD;PhosphoSitePlus	CCLE	3.158	Down-regulation
CMGC_CDK_CDC2_CDK1_ST	Q9H9S0	NANOG	P06493	CDK1	S65	P66T	66	Missense	proximal	1	no	3.327	0.893	EPSD;PhosphoSitePlus	CCLE	3.158	Loss
CMGC_CDK_CDC2_CDK1_ST	P04637	TP53	P06493	CDK1	S33	E28Q	28	Missense	distal	-5	no	3.447	3.419	EPSD	CCLE	3.158	Down-regulation
CMGC_CDK_CDC2_CDK1_ST	Q8NEB9	PIK3C3	P06493	CDK1	T159	R162K	162	Missense	distal	3	no	3.411	3.394	PhosphoSitePlus	CCLE	3.158	Down-regulation
CMGC_CDK_CDC2_CDK1_ST	Q8TD19	NEK9	P06493	CDK1	S29	A34T	34	Missense	distal	5	no	3.172	3.236	EPSD	CCLE	3.158	Up-regulation
CMGC_CDK_CDC2_CDK1_ST	Q8TD19	NEK9	P06493	CDK1	T771	S765G	765	Missense	distal	-6	no	3.249	3.272	EPSD	CCLE	3.158	Up-regulation
CMGC_CDK_CDC2_CDK1_ST	Q02952	AKAP12	P06493	CDK1	S483	K487M	487	Missense	distal	4	no	3.493	3.473	EPSD	CCLE	3.158	Down-regulation
AGC_PKG_PRKG1_ST	P04792	HSPB1	Q13976-2	PRKG1	S82	S78T	78	Missense	distal	-4	no	12.536	12.417	EPSD;PhosphoSitePlus	CCLE	7.092	Down-regulation
AGC_PKG_PRKG1_ST	Q13976	PRKG1	Q13976-2	PRKG1	T59	T59P	59	Missense	central	0	yes	8.128	0.000	EPSD	CCLE	7.092	Loss
AGC_PKG_PRKG1_ST	Q13976	PRKG1	Q13976-2	PRKG1	S65	T59P	59	Missense	distal	-6	no	8.252	8.020	EPSD;PhosphoSitePlus	CCLE	7.092	Down-regulation
AGC_PKG_PRKG1_ST	Q13153	PAK1	Q13976-2	PRKG1	S249	E255D	255	Missense	distal	6	no	8.062	8.089	EPSD	CCLE	7.092	Up-regulation
AGC_PKG_PRKG1_ST	Q13153	PAK1	Q13976-2	PRKG1	T271	T271A	271	Missense	central	0	yes	7.347	0.000	EPSD	CCLE	7.092	Loss
AGC_PKG_PRKG1_ST	Q13153	PAK1	Q13976-2	PRKG1	S491	E488K	488	Missense	distal	-3	no	4.020	8.603	EPSD	CCLE	7.092	Gain
AGC_PKG_PRKG1_ST	Q14847	LASP1	Q13976-2	PRKG1	S61	Y57H	57	Missense	distal	-4	no	7.442	7.595	EPSD	CCLE	7.092	Up-regulation
AGC_PKG_PRKG1_ST	Q14847	LASP1	Q13976-2	PRKG1	S61	S61P	61	Missense	central	0	yes	7.442	0.000	EPSD	CCLE	7.092	Loss
AGC_PKG_PRKG1_ST	Q14847	LASP1	Q13976-2	PRKG1	S99	E106Q	106	Missense	distal	7	no	7.566	7.651	EPSD	CCLE	7.092	Up-regulation
STE_STE20_PAKB_PAK4_ST	O43623	SNAI2	O96013	PAK4	S100	D93G	93	Missense	distal	-7	no	17.763	17.364	EPSD	CCLE	14.946	Down-regulation
STE_STE20_PAKB_PAK4_ST	O43623	SNAI2	O96013	PAK4	S170	L171P	171	Missense	proximal	1	no	15.232	12.358	EPSD	CCLE	14.946	Loss
STE_STE20_PAKB_PAK4_ST	O96013	PAK4	O96013	PAK4	S99	S93L	93	Missense	distal	-6	no	17.891	17.648	EPSD	CCLE	14.946	Down-regulation
STE_STE20_PAKB_PAK4_ST	O96013	PAK4	O96013	PAK4	S104	P107L	107	Missense	distal	3	no	16.271	16.815	EPSD	CCLE	14.946	Up-regulation
STE_STE20_PAKB_PAK4_ST	O96013	PAK4	O96013	PAK4	S142	A144V	144	Missense	proximal	2	no	15.389	14.882	EPSD	CCLE	14.946	Loss
STE_STE20_PAKB_PAK4_ST	O96013	PAK4	O96013	PAK4	S162	S162C	162	Missense	central	0	yes	19.330	0.000	EPSD	CCLE	14.946	Loss
STE_STE20_PAKB_PAK4_ST	O96013	PAK4	O96013	PAK4	S163	S162C	162	Missense	proximal	-1	no	15.855	13.278	EPSD	CCLE	14.946	Loss
STE_STE20_PAKB_PAK4_ST	O96013	PAK4	O96013	PAK4	S167	S162C	162	Missense	distal	-5	no	17.668	17.328	EPSD	CCLE	14.946	Down-regulation
STE_STE20_PAKB_PAK4_ST	O96013	PAK4	O96013	PAK4	S217	D214Y	214	Missense	distal	-3	no	15.691	17.394	EPSD	CCLE	14.946	Up-regulation
STE_STE20_PAKB_PAK4_ST	O96013	PAK4	O96013	PAK4	S474	V476I	476	Missense	proximal	2	no	31.770	31.231	PhosphoSitePlus	CCLE	14.946	Down-regulation
STE_STE20_PAKB_PAK4_ST	O00401	WASL	O96013	PAK4	S62	S58A	58	Missense	distal	-4	no	18.080	17.884	EPSD	CCLE	14.946	Down-regulation
STE_STE20_PAKB_PAK4_ST	O00401	WASL	O96013	PAK4	S484	E491D	491	Missense	distal	7	no	24.018	24.156	PhosphoSitePlus;EPSD	CCLE	14.946	Up-regulation
STE_STE20_PAKB_PAK4_ST	O00401	WASL	O96013	PAK4	S484	D488V	488	Missense	distal	4	no	24.018	24.154	PhosphoSitePlus;EPSD	CCLE	14.946	Up-regulation
STE_STE20_PAKB_PAK4_ST	O00401	WASL	O96013	PAK4	S485	E491D	491	Missense	distal	6	no	25.842	25.793	EPSD;PhosphoSitePlus	CCLE	14.946	Down-regulation
STE_STE20_PAKB_PAK4_ST	O00401	WASL	O96013	PAK4	S485	D488V	488	Missense	distal	3	no	25.842	25.705	EPSD;PhosphoSitePlus	CCLE	14.946	Down-regulation
STE_STE20_PAKB_PAK4_ST	P18084	ITGB5	O96013	PAK4	S759	Y766N	766	Missense	distal	7	no	26.078	26.052	PhosphoSitePlus;EPSD	CCLE	14.946	Down-regulation
STE_STE20_PAKB_PAK4_ST	P18084	ITGB5	O96013	PAK4	S759	R761Q	761	Missense	proximal	2	no	26.078	26.744	PhosphoSitePlus;EPSD	CCLE	14.946	Up-regulation
STE_STE20_PAKB_PAK4_ST	P18084	ITGB5	O96013	PAK4	S762	Y766N	766	Missense	distal	4	no	23.858	24.001	EPSD;PhosphoSitePlus	CCLE	14.946	Up-regulation
STE_STE20_PAKB_PAK4_ST	P18084	ITGB5	O96013	PAK4	S762	R761Q	761	Missense	proximal	-1	no	23.858	20.518	EPSD;PhosphoSitePlus	CCLE	14.946	Down-regulation
STE_STE20_PAKB_PAK4_ST	P18084	ITGB5	O96013	PAK4	S770	Y766N	766	Missense	distal	-4	no	18.652	18.759	EPSD	CCLE	14.946	Up-regulation
STE_STE20_PAKB_PAK4_ST	P49023	PXN	O96013	PAK4	S244	E241K	241	Missense	distal	-3	no	10.234	16.185	EPSD	CCLE	14.946	Gain
STE_STE20_PAKB_PAK4_ST	Q92974	ARHGEF2	O96013	PAK4	S142	A147T	147	Missense	distal	5	no	17.668	17.714	EPSD	CCLE	14.946	Up-regulation
STE_STE20_PAKB_PAK4_ST	Q92974	ARHGEF2	O96013	PAK4	S143	A147T	147	Missense	distal	4	no	23.198	23.178	EPSD	CCLE	14.946	Down-regulation
STE_STE20_PAKB_PAK4_ST	Q92974	ARHGEF2	O96013	PAK4	S149	A147T	147	Missense	proximal	-2	no	16.507	14.218	EPSD	CCLE	14.946	Loss
STE_STE20_PAKB_PAK4_ST	Q92974	ARHGEF2	O96013	PAK4	S151	A147T	147	Missense	distal	-4	no	18.018	16.968	EPSD	CCLE	14.946	Down-regulation
STE_STE20_PAKB_PAK4_ST	Q92974	ARHGEF2	O96013	PAK4	S186	E193Q	193	Missense	distal	7	no	15.369	15.326	EPSD	CCLE	14.946	Down-regulation
STE_STE20_PAKB_PAK4_ST	Q92974	ARHGEF2	O96013	PAK4	S645	L646P	646	Missense	proximal	1	no	19.060	16.187	EPSD	CCLE	14.946	Down-regulation
STE_STE20_PAKB_PAK4_ST	Q92974	ARHGEF2	O96013	PAK4	S645	R642S	642	Missense	distal	-3	no	19.060	13.731	EPSD	CCLE	14.946	Loss
STE_STE20_PAKB_PAK4_ST	Q92974	ARHGEF2	O96013	PAK4	S782	R779Q	779	Missense	distal	-3	no	18.870	13.346	EPSD	CCLE	14.946	Loss
STE_STE20_PAKB_PAK4_ST	P03372	ESR1	O96013	PAK4	S236	A239D	239	Missense	distal	3	no	17.263	17.527	EPSD	CCLE	14.946	Up-regulation
CAMK_MLCK_MYLK2_ST	Q06413	MEF2C	Q9H1R3	MYLK2	T70	N73K	73	Missense	distal	3	no	3.520	3.428	EPSD	CCLE	3.166	Down-regulation
CAMK_MLCK_MYLK2_ST	Q06413	MEF2C	Q9H1R3	MYLK2	T70	V65M	65	Missense	distal	-5	no	3.520	3.303	EPSD	CCLE	3.166	Down-regulation
CAMK_MLCK_MYLK2_ST	Q06413	MEF2C	Q9H1R3	MYLK2	T80	N73K	73	Missense	distal	-7	no	7.263	7.206	PhosphoSitePlus	CCLE	3.166	Down-regulation
CAMK_RAD53_CHEK2_ST	O00716	E2F3	O96017	CHEK2	S124	G126S	126	Missense	proximal	2	no	13.499	13.564	PhosphoSitePlus	CCLE	8.561	Up-regulation
CAMK_RAD53_CHEK2_ST	O43255	SIAH2	O96017	CHEK2	T26	P19L	19	Missense	distal	-7	no	10.757	10.048	EPSD;PhosphoSitePlus	CCLE	8.561	Down-regulation
CAMK_RAD53_CHEK2_ST	O43255	SIAH2	O96017	CHEK2	T119	L125Q	125	Missense	distal	6	no	10.063	9.970	EPSD;PhosphoSitePlus	CCLE	8.561	Down-regulation
CAMK_RAD53_CHEK2_ST	O96017	CHEK2	O96017	CHEK2	T432	S435L	435	Missense	distal	3	no	8.836	9.005	EPSD;PhosphoSitePlus	CCLE	8.561	Up-regulation
CAMK_RAD53_CHEK2_ST	O96017	CHEK2	O96017	CHEK2	S435	S435L	435	Missense	central	0	yes	10.217	0.000	EPSD;PhosphoSitePlus	CCLE	8.561	Loss
CAMK_RAD53_CHEK2_ST	O96017	CHEK2	O96017	CHEK2	S516	R521Q	521	Missense	distal	5	no	9.518	9.423	EPSD;PhosphoSitePlus	CCLE	8.561	Down-regulation
CAMK_RAD53_CHEK2_ST	O96017	CHEK2	O96017	CHEK2	S516	L512I	512	Missense	distal	-4	no	9.518	9.071	EPSD;PhosphoSitePlus	CCLE	8.561	Down-regulation
CAMK_RAD53_CHEK2_ST	P33981	TTK	O96017	CHEK2	S214	A211T	211	Missense	distal	-3	no	11.199	8.370	EPSD	CCLE	8.561	Loss
CAMK_RAD53_CHEK2_ST	Q9NY61	AATF	O96017	CHEK2	S61	D66Y	66	Missense	distal	5	no	9.536	9.458	EPSD	CCLE	8.561	Down-regulation
CAMK_RAD53_CHEK2_ST	Q9NY61	AATF	O96017	CHEK2	T412	T410I	410	Missense	proximal	-2	no	12.808	12.526	EPSD	CCLE	8.561	Down-regulation
CAMK_RAD53_CHEK2_ST	Q08050	FOXM1	O96017	CHEK2	S340	L334S	334	Missense	distal	-6	no	9.446	9.771	EPSD	CCLE	8.561	Up-regulation
CAMK_RAD53_CHEK2_ST	Q08050	FOXM1	O96017	CHEK2	S516	K514N	514	Missense	proximal	-2	no	8.646	8.247	EPSD	CCLE	8.561	Loss
CAMK_RAD53_CHEK2_ST	Q08050	FOXM1	O96017	CHEK2	T524	M530I	530	Missense	distal	6	no	10.662	10.547	EPSD	CCLE	8.561	Down-regulation
CAMK_RAD53_CHEK2_ST	P18887	XRCC1	O96017	CHEK2	S210	P206L	206	Missense	distal	-4	no	8.655	7.878	EPSD;PhosphoSitePlus	CCLE	8.561	Loss
CAMK_RAD53_CHEK2_ST	P18887	XRCC1	O96017	CHEK2	T358	D352E	352	Missense	distal	-6	no	11.769	12.087	EPSD	CCLE	8.561	Up-regulation
CAMK_RAD53_CHEK2_ST	P18887	XRCC1	O96017	CHEK2	S447	P448A	448	Missense	proximal	1	no	10.033	10.097	EPSD	CCLE	8.561	Up-regulation
CAMK_RAD53_CHEK2_ST	P18887	XRCC1	O96017	CHEK2	S447	S446R	446	Missense	proximal	-1	no	10.033	9.725	EPSD	CCLE	8.561	Down-regulation
CAMK_RAD53_CHEK2_ST	P30304	CDC25A	O96017	CHEK2	S178	Q174H	174	Missense	distal	-4	no	13.985	13.528	EPSD;PhosphoSitePlus	CCLE	8.561	Down-regulation
CAMK_RAD53_CHEK2_ST	P30304	CDC25A	O96017	CHEK2	S505	R506W	506	Missense	proximal	1	no	10.310	9.430	EPSD	CCLE	8.561	Down-regulation
CAMK_RAD53_CHEK2_ST	P30304	CDC25A	O96017	CHEK2	S505	L498P	498	Missense	distal	-7	no	10.310	11.019	EPSD	CCLE	8.561	Up-regulation
CAMK_RAD53_CHEK2_ST	Q9UHR4	BAIAP2L1	O96017	CHEK2	S136	L140S	140	Missense	distal	4	no	11.660	11.340	EPSD	CCLE	8.561	Down-regulation
CAMK_RAD53_CHEK2_ST	Q9UHR4	BAIAP2L1	O96017	CHEK2	S147	L140S	140	Missense	distal	-7	no	12.676	13.622	EPSD	CCLE	8.561	Up-regulation
CAMK_RAD53_CHEK2_ST	Q9NRM7	LATS2	O96017	CHEK2	S380	K383R	383	Missense	distal	3	no	18.133	17.332	EPSD;PhosphoSitePlus	CCLE	8.561	Down-regulation
CAMK_RAD53_CHEK2_ST	Q9NRM7	LATS2	O96017	CHEK2	S528	Y531H	531	Missense	distal	3	no	13.147	12.674	EPSD	CCLE	8.561	Down-regulation
CAMK_RAD53_CHEK2_ST	P29590	PML	O96017	CHEK2	S208	P210L	210	Missense	proximal	2	no	11.438	11.242	EPSD	CCLE	8.561	Down-regulation
CAMK_RAD53_CHEK2_ST	P29590	PML	O96017	CHEK2	T391	L386P	386	Missense	distal	-5	no	8.629	8.840	EPSD	CCLE	8.561	Up-regulation
CAMK_RAD53_CHEK2_ST	Q01094	E2F1	O96017	CHEK2	S313	G309R	309	Missense	distal	-4	no	10.615	11.570	EPSD	CCLE	8.561	Up-regulation
CAMK_RAD53_CHEK2_ST	Q01094	E2F1	O96017	CHEK2	S364	R366W	366	Missense	proximal	2	no	16.027	15.435	PhosphoSitePlus	CCLE	8.561	Down-regulation
CAMK_RAD53_CHEK2_ST	Q01094	E2F1	O96017	CHEK2	S382	E385D	385	Missense	distal	3	no	9.663	10.323	EPSD	CCLE	8.561	Up-regulation
CAMK_RAD53_CHEK2_ST	P10636	MAPT	O96017	CHEK2	T167	E161Q	161	Missense	distal	-6	no	11.981	12.073	EPSD	CCLE	8.561	Up-regulation
CAMK_RAD53_CHEK2_ST	P10636	MAPT	O96017	CHEK2	T167	P170F	170	Missense	distal	3	no	11.981	12.545	EPSD	CCLE	8.561	Up-regulation
CAMK_RAD53_CHEK2_ST	P10636	MAPT	O96017	CHEK2	S171	P170F	170	Missense	proximal	-1	no	11.678	12.257	EPSD	CCLE	8.561	Up-regulation
CAMK_RAD53_CHEK2_ST	P10636	MAPT	O96017	CHEK2	S171	G174A	174	Missense	distal	3	no	11.678	10.968	EPSD	CCLE	8.561	Down-regulation
CAMK_RAD53_CHEK2_ST	P10636	MAPT	O96017	CHEK2	S214	D221Y	221	Missense	distal	7	no	11.886	11.893	EPSD	CCLE	8.561	Up-regulation
CAMK_RAD53_CHEK2_ST	P10636	MAPT	O96017	CHEK2	T403	K405R	405	Missense	proximal	2	no	8.883	8.938	EPSD	CCLE	8.561	Up-regulation
CAMK_RAD53_CHEK2_ST	P10636	MAPT	O96017	CHEK2	S411	K405R	405	Missense	distal	-6	no	9.726	9.817	EPSD	CCLE	8.561	Up-regulation
CAMK_RAD53_CHEK2_ST	P10636	MAPT	O96017	CHEK2	T522	G518S	518	Missense	distal	-4	no	7.517	8.596	EPSD	CCLE	8.561	Gain
CAMK_RAD53_CHEK2_ST	P10636	MAPT	O96017	CHEK2	T529	R526L	526	Missense	distal	-3	no	13.293	5.682	EPSD	CCLE	8.561	Loss
CAMK_RAD53_CHEK2_ST	P10636	MAPT	O96017	CHEK2	S531	R526L	526	Missense	distal	-5	no	16.601	16.655	EPSD	CCLE	8.561	Up-regulation
CAMK_RAD53_CHEK2_ST	P10636	MAPT	O96017	CHEK2	T562	R559H	559	Missense	distal	-3	no	14.243	10.511	EPSD	CCLE	8.561	Down-regulation
CAMK_RAD53_CHEK2_ST	P10636	MAPT	O96017	CHEK2	S579	K574N	574	Missense	distal	-5	no	8.875	8.391	EPSD	CCLE	8.561	Loss
CAMK_RAD53_CHEK2_ST	P10636	MAPT	O96017	CHEK2	T703	G706V	706	Missense	distal	3	no	8.687	8.642	EPSD	CCLE	8.561	Down-regulation
CAMK_RAD53_CHEK2_ST	P54132	BLM	O96017	CHEK2	S314	I309F	309	Missense	distal	-5	no	8.881	8.800	EPSD	CCLE	8.561	Down-regulation
CAMK_RAD53_CHEK2_ST	P54132	BLM	O96017	CHEK2	S539	N541Y	541	Missense	proximal	2	no	9.677	9.305	EPSD	CCLE	8.561	Down-regulation
CAMK_RAD53_CHEK2_ST	P54132	BLM	O96017	CHEK2	S539	R545S	545	Missense	distal	6	no	9.677	9.612	EPSD	CCLE	8.561	Down-regulation
CAMK_RAD53_CHEK2_ST	P54132	BLM	O96017	CHEK2	S729	L730F	730	Missense	proximal	1	no	9.186	11.134	EPSD	CCLE	8.561	Up-regulation
CAMK_RAD53_CHEK2_ST	P38398	BRCA1	O96017	CHEK2	S316	R315M	315	Missense	proximal	-1	no	8.320	8.671	EPSD	CCLE	8.561	Gain
CAMK_RAD53_CHEK2_ST	P38398	BRCA1	O96017	CHEK2	S844	E851G	851	Missense	distal	7	no	10.747	10.738	EPSD	CCLE	8.561	Down-regulation
CAMK_RAD53_CHEK2_ST	P38398	BRCA1	O96017	CHEK2	S988	F989L	989	Missense	proximal	1	no	10.468	8.520	PhosphoSitePlus	CCLE	8.561	Loss
CAMK_RAD53_CHEK2_ST	P38398	BRCA1	O96017	CHEK2	S1328	M1324V	1324	Missense	distal	-4	no	10.823	10.808	EPSD	CCLE	8.561	Down-regulation
CAMK_RAD53_CHEK2_ST	P40337	VHL	O96017	CHEK2	S72	E70D	70	Missense	proximal	-2	no	15.594	15.286	EPSD	CCLE	8.561	Down-regulation
CAMK_RAD53_CHEK2_ST	Q13263	TRIM28	O96017	CHEK2	S43	S37L	37	Missense	distal	-6	no	9.443	9.118	EPSD	CCLE	8.561	Down-regulation
CAMK_RAD53_CHEK2_ST	Q13263	TRIM28	O96017	CHEK2	S43	A38V	38	Missense	distal	-5	no	9.443	9.369	EPSD	CCLE	8.561	Down-regulation
CAMK_RAD53_CHEK2_ST	Q13263	TRIM28	O96017	CHEK2	S43	S41W	41	Missense	proximal	-2	no	9.443	8.072	EPSD	CCLE	8.561	Loss
CAMK_RAD53_CHEK2_ST	Q13263	TRIM28	O96017	CHEK2	S43	A44P	44	Missense	proximal	1	no	9.443	9.380	EPSD	CCLE	8.561	Down-regulation
CAMK_RAD53_CHEK2_ST	Q13263	TRIM28	O96017	CHEK2	S43	A46S	46	Missense	distal	3	no	9.443	9.453	EPSD	CCLE	8.561	Up-regulation
CAMK_RAD53_CHEK2_ST	Q13263	TRIM28	O96017	CHEK2	S50	A44P	44	Missense	distal	-6	no	10.211	10.312	EPSD	CCLE	8.561	Up-regulation
CAMK_RAD53_CHEK2_ST	Q13263	TRIM28	O96017	CHEK2	S50	A46S	46	Missense	distal	-4	no	10.211	10.371	EPSD	CCLE	8.561	Up-regulation
CAMK_RAD53_CHEK2_ST	Q13263	TRIM28	O96017	CHEK2	S102	A98T	98	Missense	distal	-4	no	9.036	8.257	EPSD	CCLE	8.561	Loss
CAMK_RAD53_CHEK2_ST	P30307	CDC25C	O96017	CHEK2	S449	G456R	456	Missense	distal	7	no	13.832	13.821	EPSD	CCLE	8.561	Down-regulation
CAMK_RAD53_CHEK2_ST	P30307	CDC25C	O96017	CHEK2	S451	G456R	456	Missense	distal	5	no	9.972	10.214	EPSD	CCLE	8.561	Up-regulation
CAMK_RAD53_CHEK2_ST	P06400	RB1	O96017	CHEK2	S588	D584E	584	Missense	distal	-4	no	7.763	8.840	EPSD	CCLE	8.561	Gain
CAMK_RAD53_CHEK2_ST	P06400	RB1	O96017	CHEK2	S612	P609H	609	Missense	distal	-3	no	7.619	9.613	PhosphoSitePlus	CCLE	8.561	Gain
CAMK_RAD53_CHEK2_ST	O60673	REV3L	O96017	CHEK2	S545	T543A	543	Missense	proximal	-2	no	10.208	10.353	EPSD	CCLE	8.561	Up-regulation
CAMK_RAD53_CHEK2_ST	O60673	REV3L	O96017	CHEK2	S1130	W1129C	1129	Missense	proximal	-1	no	16.877	16.164	EPSD	CCLE	8.561	Down-regulation
CAMK_RAD53_CHEK2_ST	O60673	REV3L	O96017	CHEK2	S1757	C1763R	1763	Missense	distal	6	no	14.520	14.725	EPSD	CCLE	8.561	Up-regulation
CAMK_RAD53_CHEK2_ST	O60673	REV3L	O96017	CHEK2	S2714	R2711K	2711	Missense	distal	-3	no	9.330	4.245	EPSD	CCLE	8.561	Loss
CAMK_CAMK2_CAMK2D_ST	Q08289	CACNB2	Q13557	CAMK2D	S534	S532T	532	Missense	proximal	-2	no	49.774	48.949	EPSD	CCLE	37.605	Down-regulation
CAMK_CAMK2_CAMK2D_ST	Q08289	CACNB2	Q13557	CAMK2D	S550	F555L	555	Missense	distal	5	no	41.780	42.749	EPSD	CCLE	37.605	Up-regulation
CAMK_CAMK2_CAMK2D_ST	Q08289	CACNB2	Q13557	CAMK2D	T554	F555L	555	Missense	proximal	1	no	87.151	78.596	EPSD	CCLE	37.605	Down-regulation
CAMK_CAMK2_CAMK2D_ST	P51787	KCNQ1	Q13557	CAMK2D	S27	P21Q	21	Missense	distal	-6	no	34.194	40.506	EPSD	CCLE	37.605	Gain
CAMK_CAMK2_CAMK2D_ST	P51787	KCNQ1	Q13557	CAMK2D	T470	R466G	466	Missense	distal	-4	no	43.465	41.166	EPSD	CCLE	37.605	Down-regulation
CAMK_CAMK2_CAMK2D_ST	P56524	HDAC4	Q13557	CAMK2D	S246	L252S	252	Missense	distal	6	no	37.379	37.821	EPSD	CCLE	37.605	Gain
CAMK_CAMK2_CAMK2D_ST	P56524	HDAC4	Q13557	CAMK2D	S620	G622V	622	Missense	proximal	2	no	38.429	31.854	EPSD	CCLE	37.605	Loss
CAMK_CAMK2_CAMK2D_ST	P56524	HDAC4	Q13557	CAMK2D	S620	V619M	619	Missense	proximal	-1	no	38.429	36.263	EPSD	CCLE	37.605	Loss
CAMK_CAMK2_CAMK2D_ST	P56524	HDAC4	Q13557	CAMK2D	S628	A635V	635	Missense	distal	7	no	51.960	51.905	EPSD	CCLE	37.605	Down-regulation
CAMK_CAMK2_CAMK2D_ST	P56524	HDAC4	Q13557	CAMK2D	S628	G622V	622	Missense	distal	-6	no	51.960	46.553	EPSD	CCLE	37.605	Down-regulation
CAMK_CAMK2_CAMK2D_ST	P56524	HDAC4	Q13557	CAMK2D	S632	A635V	635	Missense	distal	3	no	41.998	20.766	EPSD	CCLE	37.605	Loss
CAMK_CAMK2_CAMK2D_ST	Q8WZ42	TTN	Q13557	CAMK2D	T334	T330A	330	Missense	distal	-4	no	52.348	51.932	EPSD	CCLE	37.605	Down-regulation
CAMK_CAMK2_CAMK2D_ST	Q8WZ42	TTN	Q13557	CAMK2D	S353	S354A	354	Missense	proximal	1	no	51.118	46.761	EPSD	CCLE	37.605	Down-regulation
CAMK_CAMK2_CAMK2D_ST	Q8WZ42	TTN	Q13557	CAMK2D	S353	K346R	346	Missense	distal	-7	no	51.118	49.529	EPSD	CCLE	37.605	Down-regulation
CAMK_CAMK2_CAMK2D_ST	Q8WZ42	TTN	Q13557	CAMK2D	S837	A840D	840	Missense	distal	3	no	48.246	32.246	EPSD	CCLE	37.605	Loss
CAMK_CAMK2_CAMK2D_ST	Q8WZ42	TTN	Q13557	CAMK2D	T1067	S1068C	1068	Missense	proximal	1	no	41.928	37.351	EPSD	CCLE	37.605	Loss
CAMK_CAMK2_CAMK2D_ST	Q8WZ42	TTN	Q13557	CAMK2D	T1973	V1976N	1976	Missense	distal	3	no	27.094	40.753	EPSD	CCLE	37.605	Gain
CAMK_CAMK2_CAMK2D_ST	Q8WZ42	TTN	Q13557	CAMK2D	S2749	N2750S	2750	Missense	proximal	1	no	45.043	44.816	EPSD	CCLE	37.605	Down-regulation
CAMK_CAMK2_CAMK2D_ST	Q8WZ42	TTN	Q13557	CAMK2D	T3119	A3124T	3124	Missense	distal	5	no	55.190	54.126	EPSD	CCLE	37.605	Down-regulation
CAMK_CAMK2_CAMK2D_ST	Q8WZ42	TTN	Q13557	CAMK2D	S3252	R3257H	3257	Missense	distal	5	no	37.511	38.314	EPSD	CCLE	37.605	Gain
CAMK_CAMK2_CAMK2D_ST	Q8WZ42	TTN	Q13557	CAMK2D	S4065	L4060I	4060	Missense	distal	-5	no	48.809	48.878	EPSD	CCLE	37.605	Up-regulation
CAMK_CAMK2_CAMK2D_ST	Q8WZ42	TTN	Q13557	CAMK2D	S5083	R5085T	5085	Missense	proximal	2	no	38.068	35.603	EPSD	CCLE	37.605	Loss
CAMK_CAMK2_CAMK2D_ST	Q8WZ42	TTN	Q13557	CAMK2D	S6205	D6200E	6200	Missense	distal	-5	no	39.253	38.793	EPSD	CCLE	37.605	Down-regulation
CAMK_CAMK2_CAMK2D_ST	Q8WZ42	TTN	Q13557	CAMK2D	S7613	S7616N	7616	Missense	distal	3	no	45.107	43.997	EPSD	CCLE	37.605	Down-regulation
CAMK_CAMK2_CAMK2D_ST	Q8WZ42	TTN	Q13557	CAMK2D	S7649	S7643I	7643	Missense	distal	-6	no	38.831	35.969	EPSD	CCLE	37.605	Loss
CAMK_CAMK2_CAMK2D_ST	Q8WZ42	TTN	Q13557	CAMK2D	T9189	G9191W	9191	Missense	proximal	2	no	43.771	39.791	EPSD	CCLE	37.605	Down-regulation
CAMK_CAMK2_CAMK2D_ST	Q8WZ42	TTN	Q13557	CAMK2D	S9633	D9628N	9628	Missense	distal	-5	no	39.074	39.116	EPSD	CCLE	37.605	Up-regulation
CAMK_CAMK2_CAMK2D_ST	Q8WZ42	TTN	Q13557	CAMK2D	T10581	E10574K	10574	Missense	distal	-7	no	53.675	59.942	EPSD	CCLE	37.605	Up-regulation
CAMK_CAMK2_CAMK2D_ST	Q8WZ42	TTN	Q13557	CAMK2D	T10658	E10654K	10654	Missense	distal	-4	no	53.104	56.359	EPSD	CCLE	37.605	Up-regulation
CAMK_CAMK2_CAMK2D_ST	Q8WZ42	TTN	Q13557	CAMK2D	S10781	K10777N	10777	Missense	distal	-4	no	39.141	35.239	EPSD	CCLE	37.605	Loss
CAMK_CAMK2_CAMK2D_ST	Q8WZ42	TTN	Q13557	CAMK2D	S12902	G12907V	12907	Missense	distal	5	no	53.372	54.379	EPSD	CCLE	37.605	Up-regulation
CAMK_CAMK2_CAMK2D_ST	Q8WZ42	TTN	Q13557	CAMK2D	S12902	L12895R	12895	Missense	distal	-7	no	53.372	52.091	EPSD	CCLE	37.605	Down-regulation
CAMK_CAMK2_CAMK2D_ST	Q8WZ42	TTN	Q13557	CAMK2D	S12911	G12907V	12907	Missense	distal	-4	no	37.323	40.438	EPSD	CCLE	37.605	Gain
CAMK_CAMK2_CAMK2D_ST	Q8WZ42	TTN	Q13557	CAMK2D	S13802	H13804R	13804	Missense	proximal	2	no	38.601	41.557	EPSD	CCLE	37.605	Up-regulation
CAMK_CAMK2_CAMK2D_ST	Q8WZ42	TTN	Q13557	CAMK2D	T14099	E14101D	14101	Missense	proximal	2	no	44.513	51.939	EPSD	CCLE	37.605	Up-regulation
CAMK_CAMK2_CAMK2D_ST	Q8WZ42	TTN	Q13557	CAMK2D	T14099	S14092R	14092	Missense	distal	-7	no	44.513	46.572	EPSD	CCLE	37.605	Up-regulation
CAMK_CAMK2_CAMK2D_ST	Q8WZ42	TTN	Q13557	CAMK2D	S14345	L14342M	14342	Missense	distal	-3	no	35.590	47.061	EPSD	CCLE	37.605	Gain
CAMK_CAMK2_CAMK2D_ST	Q8WZ42	TTN	Q13557	CAMK2D	T14402	G14405E	14405	Missense	distal	3	no	33.147	41.062	EPSD	CCLE	37.605	Gain
CAMK_CAMK2_CAMK2D_ST	Q8WZ42	TTN	Q13557	CAMK2D	T14633	G14632E	14632	Missense	proximal	-1	no	39.528	39.674	EPSD	CCLE	37.605	Up-regulation
CAMK_CAMK2_CAMK2D_ST	Q8WZ42	TTN	Q13557	CAMK2D	S15744	W15749C	15749	Missense	distal	5	no	49.029	51.585	EPSD	CCLE	37.605	Up-regulation
CAMK_CAMK2_CAMK2D_ST	Q8WZ42	TTN	Q13557	CAMK2D	S16412	T16405I	16405	Missense	distal	-7	no	34.494	38.061	EPSD	CCLE	37.605	Gain
CAMK_CAMK2_CAMK2D_ST	Q8WZ42	TTN	Q13557	CAMK2D	S16649	W16652C	16652	Missense	distal	3	no	32.215	47.006	EPSD	CCLE	37.605	Gain
CAMK_CAMK2_CAMK2D_ST	Q8WZ42	TTN	Q13557	CAMK2D	S18513	S18518G	18518	Missense	distal	5	no	36.739	37.690	EPSD	CCLE	37.605	Gain
CAMK_CAMK2_CAMK2D_ST	Q8WZ42	TTN	Q13557	CAMK2D	S18976	W18975G	18975	Missense	proximal	-1	no	55.000	57.109	EPSD	CCLE	37.605	Up-regulation
CAMK_CAMK2_CAMK2D_ST	Q8WZ42	TTN	Q13557	CAMK2D	S18976	K18969R	18969	Missense	distal	-7	no	55.000	53.410	EPSD	CCLE	37.605	Down-regulation
CAMK_CAMK2_CAMK2D_ST	Q8WZ42	TTN	Q13557	CAMK2D	T20168	Q20172L	20172	Missense	distal	4	no	50.073	50.340	EPSD	CCLE	37.605	Up-regulation
CAMK_CAMK2_CAMK2D_ST	Q8WZ42	TTN	Q13557	CAMK2D	T20477	T20483A	20483	Missense	distal	6	no	49.398	52.991	EPSD	CCLE	37.605	Up-regulation
CAMK_CAMK2_CAMK2D_ST	Q8WZ42	TTN	Q13557	CAMK2D	T20721	K20727N	20727	Missense	distal	6	no	51.310	52.208	EPSD	CCLE	37.605	Up-regulation
CAMK_CAMK2_CAMK2D_ST	Q8WZ42	TTN	Q13557	CAMK2D	T20721	T20721A	20721	Missense	central	0	yes	51.310	0.000	EPSD	CCLE	37.605	Loss
CAMK_CAMK2_CAMK2D_ST	Q8WZ42	TTN	Q13557	CAMK2D	T20721	P20717L	20717	Missense	distal	-4	no	51.310	49.747	EPSD	CCLE	37.605	Down-regulation
CAMK_CAMK2_CAMK2D_ST	Q8WZ42	TTN	Q13557	CAMK2D	S20864	M20860I	20860	Missense	distal	-4	no	43.845	45.598	EPSD	CCLE	37.605	Up-regulation
CAMK_CAMK2_CAMK2D_ST	Q8WZ42	TTN	Q13557	CAMK2D	T20994	G21001D	21001	Missense	distal	7	no	47.634	48.625	EPSD	CCLE	37.605	Up-regulation
CAMK_CAMK2_CAMK2D_ST	Q8WZ42	TTN	Q13557	CAMK2D	T20994	V20999F	20999	Missense	distal	5	no	47.634	43.817	EPSD	CCLE	37.605	Down-regulation
CAMK_CAMK2_CAMK2D_ST	Q8WZ42	TTN	Q13557	CAMK2D	S21755	T21753R	21753	Missense	proximal	-2	no	38.251	39.608	EPSD	CCLE	37.605	Up-regulation
CAMK_CAMK2_CAMK2D_ST	Q8WZ42	TTN	Q13557	CAMK2D	T22152	E22155K	22155	Missense	distal	3	no	55.095	49.076	EPSD	CCLE	37.605	Down-regulation
CAMK_CAMK2_CAMK2D_ST	Q8WZ42	TTN	Q13557	CAMK2D	S22525	V22519A	22519	Missense	distal	-6	no	55.680	61.096	EPSD	CCLE	37.605	Up-regulation
CAMK_CAMK2_CAMK2D_ST	Q8WZ42	TTN	Q13557	CAMK2D	T22878	T22878I	22878	Missense	central	0	yes	52.521	0.000	EPSD	CCLE	37.605	Loss
CAMK_CAMK2_CAMK2D_ST	Q8WZ42	TTN	Q13557	CAMK2D	T23234	E23237D	23237	Missense	distal	3	no	48.833	36.248	EPSD	CCLE	37.605	Loss
CAMK_CAMK2_CAMK2D_ST	Q8WZ42	TTN	Q13557	CAMK2D	T23555	R23552K	23552	Missense	distal	-3	no	42.732	31.325	EPSD	CCLE	37.605	Loss
CAMK_CAMK2_CAMK2D_ST	Q8WZ42	TTN	Q13557	CAMK2D	T23620	V23614A	23614	Missense	distal	-6	no	39.475	44.890	EPSD	CCLE	37.605	Up-regulation
CAMK_CAMK2_CAMK2D_ST	Q8WZ42	TTN	Q13557	CAMK2D	S25094	A25088V	25088	Missense	distal	-6	no	48.404	42.989	EPSD	CCLE	37.605	Down-regulation
CAMK_CAMK2_CAMK2D_ST	Q8WZ42	TTN	Q13557	CAMK2D	T25283	V25287I	25287	Missense	distal	4	no	35.534	37.727	EPSD	CCLE	37.605	Gain
CAMK_CAMK2_CAMK2D_ST	Q8WZ42	TTN	Q13557	CAMK2D	T25389	I25391V	25391	Missense	proximal	2	no	41.908	36.593	EPSD	CCLE	37.605	Loss
CAMK_CAMK2_CAMK2D_ST	Q8WZ42	TTN	Q13557	CAMK2D	T25398	I25391V	25391	Missense	distal	-7	no	38.862	33.444	EPSD	CCLE	37.605	Loss
CAMK_CAMK2_CAMK2D_ST	Q8WZ42	TTN	Q13557	CAMK2D	S25442	G25436E	25436	Missense	distal	-6	no	41.732	43.122	EPSD	CCLE	37.605	Up-regulation
CAMK_CAMK2_CAMK2D_ST	Q8WZ42	TTN	Q13557	CAMK2D	S25442	P25435L	25435	Missense	distal	-7	no	41.732	48.323	EPSD	CCLE	37.605	Up-regulation
CAMK_CAMK2_CAMK2D_ST	Q8WZ42	TTN	Q13557	CAMK2D	S25507	A25508V	25508	Missense	proximal	1	no	36.196	42.628	EPSD	CCLE	37.605	Gain
CAMK_CAMK2_CAMK2D_ST	Q8WZ42	TTN	Q13557	CAMK2D	T26480	G26481V	26481	Missense	proximal	1	no	51.713	52.317	EPSD	CCLE	37.605	Up-regulation
CAMK_CAMK2_CAMK2D_ST	Q8WZ42	TTN	Q13557	CAMK2D	T28055	T28058A	28058	Missense	distal	3	no	43.336	56.464	EPSD	CCLE	37.605	Up-regulation
CAMK_CAMK2_CAMK2D_ST	Q8WZ42	TTN	Q13557	CAMK2D	S28636	S28636L	28636	Missense	central	0	yes	44.404	0.000	EPSD	CCLE	37.605	Loss
CAMK_CAMK2_CAMK2D_ST	Q8WZ42	TTN	Q13557	CAMK2D	T31011	W31006R	31006	Missense	distal	-5	no	38.227	36.291	EPSD	CCLE	37.605	Loss
CAMK_CAMK2_CAMK2D_ST	Q8WZ42	TTN	Q13557	CAMK2D	S31105	R31107L	31107	Missense	proximal	2	no	43.194	45.448	EPSD	CCLE	37.605	Up-regulation
CAMK_CAMK2_CAMK2D_ST	Q8WZ42	TTN	Q13557	CAMK2D	T32667	E32669V	32669	Missense	proximal	2	no	38.079	33.200	EPSD	CCLE	37.605	Loss
CAMK_CAMK2_CAMK2D_ST	Q8WZ42	TTN	Q13557	CAMK2D	T32911	I32912T	32912	Missense	proximal	1	no	48.992	38.792	EPSD	CCLE	37.605	Down-regulation
CAMK_CAMK2_CAMK2D_ST	Q8WZ42	TTN	Q13557	CAMK2D	T32998	D33004N	33004	Missense	distal	6	no	46.829	48.926	EPSD	CCLE	37.605	Up-regulation
CAMK_CAMK2_CAMK2D_ST	Q8WZ42	TTN	Q13557	CAMK2D	S33071	S33065Y	33065	Missense	distal	-6	no	46.247	42.928	EPSD	CCLE	37.605	Down-regulation
CAMK_CAMK2_CAMK2D_ST	Q8WZ42	TTN	Q13557	CAMK2D	S33245	P33243L	33243	Missense	proximal	-2	no	45.143	44.670	EPSD	CCLE	37.605	Down-regulation
CAMK_CAMK2_CAMK2D_ST	Q8WZ42	TTN	Q13557	CAMK2D	S33245	E33239A	33239	Missense	distal	-6	no	45.143	43.761	EPSD	CCLE	37.605	Down-regulation
CAMK_CAMK2_CAMK2D_ST	Q8WZ42	TTN	Q13557	CAMK2D	S33247	P33243L	33243	Missense	distal	-4	no	43.037	41.474	EPSD	CCLE	37.605	Down-regulation
CAMK_CAMK2_CAMK2D_ST	Q8WZ42	TTN	Q13557	CAMK2D	T33484	T33485P	33485	Missense	proximal	1	no	38.462	37.231	EPSD	CCLE	37.605	Loss
CAMK_CAMK2_CAMK2D_ST	Q8WZ42	TTN	Q13557	CAMK2D	T33485	T33485P	33485	Missense	central	0	yes	47.096	0.000	EPSD	CCLE	37.605	Loss
CAMK_CAMK2_CAMK2D_ST	Q8WZ42	TTN	Q13557	CAMK2D	T33498	E33501K	33501	Missense	distal	3	no	47.077	41.057	EPSD	CCLE	37.605	Down-regulation
CAMK_CAMK2_CAMK2D_ST	Q8WZ42	TTN	Q13557	CAMK2D	T33498	T33498I	33498	Missense	central	0	yes	47.077	0.000	EPSD	CCLE	37.605	Loss
CAMK_CAMK2_CAMK2D_ST	Q8WZ42	TTN	Q13557	CAMK2D	T33498	M33497A	33497	Missense	proximal	-1	no	47.077	47.984	EPSD	CCLE	37.605	Up-regulation
CAMK_CAMK2_CAMK2D_ST	Q8WZ42	TTN	Q13557	CAMK2D	T33626	T33628I	33628	Missense	proximal	2	no	49.680	53.772	EPSD	CCLE	37.605	Up-regulation
CAMK_CAMK2_CAMK2D_ST	Q8WZ42	TTN	Q13557	CAMK2D	S33932	V33935A	33935	Missense	distal	3	no	21.980	43.212	EPSD	CCLE	37.605	Gain
CAMK_CAMK2_CAMK2D_ST	Q14524	SCN5A	Q13557	CAMK2D	S1083	P1089S	1089	Missense	distal	6	no	51.699	45.797	EPSD	CCLE	37.605	Down-regulation
CAMK_CAMK2_CAMK2D_ST	Q14524	SCN5A	Q13557	CAMK2D	S1925	R1919H	1919	Missense	distal	-6	no	51.948	49.773	EPSD	CCLE	37.605	Down-regulation
CAMK_CAMK2_CAMK2D_ST	Q14654	KCNJ11	Q13557	CAMK2D	T224	V220A	220	Missense	distal	-4	no	73.333	71.882	PhosphoSitePlus	CCLE	37.605	Down-regulation
CAMK_CAMK2_CAMK2D_ST	Q14654	KCNJ11	Q13557	CAMK2D	S372	A378P	378	Missense	distal	6	no	37.388	40.328	EPSD	CCLE	37.605	Gain
CAMK_CAMK2_CAMK2D_ST	Q16625	OCLN	Q13557	CAMK2D	S326	M323T	323	Missense	distal	-3	no	38.813	27.547	EPSD	CCLE	37.605	Loss
CAMK_CAMK2_CAMK2D_ST	Q16625	OCLN	Q13557	CAMK2D	S370	Q365K	365	Missense	distal	-5	no	54.325	54.567	EPSD	CCLE	37.605	Up-regulation
CAMK_CAMK2_CAMK2D_ST	O15084	ANKRD28	Q13557	CAMK2D	S1011	L1015V	1015	Missense	distal	4	no	71.759	68.655	PhosphoSitePlus	CCLE	37.605	Down-regulation
AGC_GRK_GRK_GRK6_ST	Q15722	LTB4R	P43250	GRK6	S320	Q323H	323	Missense	distal	3	no	78.310	74.898	EPSD	CCLE	74.824	Down-regulation
AGC_GRK_GRK_GRK6_ST	Q16625	OCLN	P43250	GRK6	S370	Q365K	365	Missense	distal	-5	no	75.195	75.053	EPSD	CCLE	74.824	Down-regulation
STE_STE20_YSK_STK25_ST	Q9BSQ5	CCM2	O00506	STK25	S384	G377S	377	Missense	distal	-7	no	5.544	5.491	PhosphoSitePlus	CCLE	1.379	Down-regulation
TK_VEGFR_FLT1_Y	P17948	FLT1	P17948	FLT1	Y1169	I1170T	1170	Missense	proximal	1	no	5.215	5.224	EPSD;PhosphoSitePlus	CCLE	1.801	Up-regulation
Other_WNK_WNK3_ST	Q9H4A3	WNK1	Q9BYP7	WNK3	S1289	T1286I	1286	Missense	distal	-3	no	2.660	2.686	EPSD	CCLE	2.233	Up-regulation
Other_WNK_WNK3_ST	Q9H4A3	WNK1	Q9BYP7	WNK3	T1913	I1912L	1912	Missense	proximal	-1	no	2.817	2.810	EPSD	CCLE	2.233	Down-regulation
Other_WNK_WNK3_ST	Q9H4A3	WNK1	Q9BYP7	WNK3	T1913	S1919L	1919	Missense	distal	6	no	2.817	2.715	EPSD	CCLE	2.233	Down-regulation
Other_WNK_WNK3_ST	Q9UHW9	SLC12A6	Q9BYP7	WNK3	S96	N95S	95	Missense	proximal	-1	no	6.778	6.585	EPSD;PhosphoSitePlus	CCLE	2.233	Down-regulation
Other_WNK_WNK3_ST	Q9UHW9	SLC12A6	Q9BYP7	WNK3	S120	Y122D	122	Missense	proximal	2	no	3.253	3.187	EPSD	CCLE	2.233	Down-regulation
Other_WNK_WNK3_ST	Q9UHW9	SLC12A6	Q9BYP7	WNK3	T1028	R1021Q	1021	Missense	distal	-7	no	2.932	2.687	EPSD	CCLE	2.233	Down-regulation
Other_WNK_WNK3_ST	Q9UHW9	SLC12A6	Q9BYP7	WNK3	T1038	E1039K	1039	Missense	proximal	1	no	2.422	2.522	EPSD	CCLE	2.233	Up-regulation
Other_WNK_WNK3_ST	Q9UHW9	SLC12A6	Q9BYP7	WNK3	T1040	E1039K	1039	Missense	proximal	-1	no	2.239	2.350	EPSD	CCLE	2.233	Up-regulation
TK_InsR_IGF1R_Y	P35568	IRS1	P08069	IGF1R	Y47	E48D	48	Missense	proximal	1	no	3.370	3.161	EPSD	CCLE	3.025	Down-regulation
TK_InsR_IGF1R_Y	P35568	IRS1	P08069	IGF1R	Y732	V738M	738	Missense	distal	6	no	3.821	3.787	EPSD;PhosphoSitePlus	CCLE	3.025	Down-regulation
TK_InsR_IGF1R_Y	P35568	IRS1	P08069	IGF1R	Y764	L767V	767	Missense	distal	3	no	3.961	4.000	EPSD	CCLE	3.025	Up-regulation
TK_InsR_IGF1R_Y	P35568	IRS1	P08069	IGF1R	Y896	G902L	902	Missense	distal	6	no	5.717	5.714	EPSD;PhosphoSitePlus	CCLE	3.025	Down-regulation
TK_InsR_IGF1R_Y	P35568	IRS1	P08069	IGF1R	Y941	K943N	943	Missense	proximal	2	no	5.533	6.500	EPSD;PhosphoSitePlus	CCLE	3.025	Up-regulation
TK_InsR_IGF1R_Y	O15530	PDPK1	P08069	IGF1R	Y156	E153K	153	Missense	distal	-3	no	3.026	2.697	EPSD	CCLE	3.025	Loss
TK_InsR_IGF1R_Y	O15530	PDPK1	P08069	IGF1R	Y373	E370K	370	Missense	distal	-3	no	4.041	3.711	EPSD;PhosphoSitePlus	CCLE	3.025	Down-regulation
TK_InsR_IGF1R_Y	O15530	PDPK1	P08069	IGF1R	Y376	E370K	370	Missense	distal	-6	no	5.561	5.574	PhosphoSitePlus;EPSD	CCLE	3.025	Up-regulation
TK_InsR_IGF1R_Y	P07355	ANXA2	P08069	IGF1R	Y232	S234R	234	Missense	proximal	2	no	3.225	2.040	EPSD	CCLE	3.025	Loss
TK_InsR_IGF1R_Y	P07355	ANXA2	P08069	IGF1R	Y238	M240V	240	Missense	proximal	2	no	3.332	2.990	EPSD	CCLE	3.025	Loss
TK_InsR_IGF1R_Y	P07355	ANXA2	P08069	IGF1R	Y238	S234R	234	Missense	distal	-4	no	3.332	3.257	EPSD	CCLE	3.025	Down-regulation
TK_InsR_IGF1R_Y	P78324	SIRPA	P08069	IGF1R	Y470	A463S	463	Missense	distal	-7	no	4.343	4.059	EPSD;PhosphoSitePlus	CCLE	3.025	Down-regulation
TK_InsR_IGF1R_Y	P78324	SIRPA	P08069	IGF1R	Y470	L473P	473	Missense	distal	3	no	4.343	3.951	EPSD;PhosphoSitePlus	CCLE	3.025	Down-regulation
TKL_MLK_MLK_MAP3K10_ST	Q92630	DYRK2	Q02779	MAP3K10	S30	V24I	24	Missense	distal	-6	no	2.138	1.992	EPSD	CCLE	2.080	Loss
TKL_MLK_MLK_MAP3K10_ST	Q92630	DYRK2	Q02779	MAP3K10	S48	L52P	52	Missense	distal	4	no	2.449	2.458	EPSD	CCLE	2.080	Up-regulation
TKL_MLK_MLK_MAP3K10_ST	Q92630	DYRK2	Q02779	MAP3K10	S48	P54H	54	Missense	distal	6	no	2.449	2.625	EPSD	CCLE	2.080	Up-regulation
TKL_MLK_MLK_MAP3K10_ST	Q92630	DYRK2	Q02779	MAP3K10	S471	T466A	466	Missense	distal	-5	no	2.994	2.836	EPSD	CCLE	2.080	Down-regulation
TKL_MLK_MLK_MAP3K10_ST	Q92630	DYRK2	Q02779	MAP3K10	S471	T466S	466	Missense	distal	-5	no	2.994	2.855	EPSD	CCLE	2.080	Down-regulation
TKL_MLK_MLK_MAP3K10_ST	P15923	TCF3	Q02779	MAP3K10	S39	G42R	42	Missense	distal	3	no	2.468	2.508	EPSD	CCLE	2.080	Up-regulation
TKL_MLK_MLK_MAP3K10_ST	P15923	TCF3	Q02779	MAP3K10	S39	A38V	38	Missense	proximal	-1	no	2.468	2.434	EPSD	CCLE	2.080	Down-regulation
TKL_MLK_MLK_MAP3K10_ST	P15923	TCF3	Q02779	MAP3K10	S305	V304I	304	Missense	proximal	-1	no	2.628	2.665	EPSD	CCLE	2.080	Up-regulation
TKL_MLK_MLK_MAP3K10_ST	P15923	TCF3	Q02779	MAP3K10	T308	V304I	304	Missense	distal	-4	no	3.595	3.379	EPSD	CCLE	2.080	Down-regulation
TKL_MLK_MLK_MAP3K10_ST	P15923	TCF3	Q02779	MAP3K10	S341	S345L	345	Missense	distal	4	no	5.783	5.683	EPSD;PhosphoSitePlus	CCLE	2.080	Down-regulation
TKL_MLK_MLK_MAP3K10_ST	P15923	TCF3	Q02779	MAP3K10	S352	S345L	345	Missense	distal	-7	no	5.668	5.444	EPSD;PhosphoSitePlus	CCLE	2.080	Down-regulation
TKL_MLK_MLK_MAP3K10_ST	P15923	TCF3	Q02779	MAP3K10	S379	A377V	377	Missense	proximal	-2	no	5.985	5.933	EPSD;PhosphoSitePlus	CCLE	2.080	Down-regulation
TKL_MLK_MLK_MAP3K10_ST	P15923	TCF3	Q02779	MAP3K10	S379	A374D	374	Missense	distal	-5	no	5.985	6.165	EPSD;PhosphoSitePlus	CCLE	2.080	Up-regulation
TKL_STKR_STKR2_TGFBR2_ST	P37173	TGFBR2	P37173	TGFBR2	S213	A217V	217	Missense	distal	4	no	1.789	1.816	EPSD;PhosphoSitePlus	CCLE	0.983	Up-regulation
TKL_STKR_STKR2_TGFBR2_ST	P37173	TGFBR2	P37173	TGFBR2	S409	R403C	403	Missense	distal	-6	no	1.938	1.966	EPSD;PhosphoSitePlus	CCLE	0.983	Up-regulation
TKL_STKR_STKR2_TGFBR2_ST	P37173	TGFBR2	P37173	TGFBR2	S409	S409F	409	Missense	central	0	yes	1.938	0.000	EPSD;PhosphoSitePlus	CCLE	0.983	Loss
TKL_STKR_STKR2_TGFBR2_ST	P37173	TGFBR2	P37173	TGFBR2	S416	S409F	409	Missense	distal	-7	no	1.977	1.983	EPSD;PhosphoSitePlus	CCLE	0.983	Up-regulation
TKL_STKR_STKR2_TGFBR2_ST	O75604	USP2	P37173	TGFBR2	S58	F59V	59	Missense	proximal	1	no	0.988	1.049	EPSD	CCLE	0.983	Up-regulation
CMGC_CLK_CLK1_ST	P00519	ABL1	P49759	CLK1	S642	R639Q	639	Missense	distal	-3	no	70.448	44.658	EPSD	CCLE	52.547	Loss
CMGC_CLK_CLK1_ST	P00519	ABL1	P49759	CLK1	S642	A647D	647	Missense	distal	5	no	70.448	68.356	EPSD	CCLE	52.547	Down-regulation
CMGC_CLK_CLK1_ST	P00519	ABL1	P49759	CLK1	S695	T700I	700	Missense	distal	5	no	56.336	55.951	EPSD	CCLE	52.547	Down-regulation
CMGC_CLK_CLK1_ST	P00519	ABL1	P49759	CLK1	S919	P914L	914	Missense	distal	-5	no	51.548	60.937	EPSD	CCLE	52.547	Gain
CMGC_CLK_CLK1_ST	P00519	ABL1	P49759	CLK1	S936	T935M	935	Missense	proximal	-1	no	55.186	55.167	EPSD	CCLE	52.547	Down-regulation
CMGC_CLK_CLK1_ST	Q96I25	RBM17	P49759	CLK1	S48	R44W	44	Missense	distal	-4	no	95.061	94.600	EPSD;PhosphoSitePlus	CCLE	52.547	Down-regulation
CMGC_CLK_CLK1_ST	Q96I25	RBM17	P49759	CLK1	S62	G60S	60	Missense	proximal	-2	no	98.929	107.230	EPSD;PhosphoSitePlus	CCLE	52.547	Up-regulation
CMGC_CLK_CLK1_ST	P18031	PTPN1	P49759	CLK1	S50	P51S	51	Missense	proximal	1	no	105.509	104.938	EPSD;PhosphoSitePlus	CCLE	52.547	Down-regulation
CAMK_CAMKL_BRSK_BRSK2_ST	Q13131	PRKAA1	Q8IWQ3	BRSK2	S517	L521V	521	Missense	distal	4	no	3.417	3.049	EPSD	CCLE	3.184	Loss
CAMK_CAMKL_BRSK_BRSK2_ST	P49815	TSC2	Q8IWQ3	BRSK2	T993	L995I	995	Missense	proximal	2	no	3.697	3.698	EPSD	CCLE	3.184	Up-regulation
CAMK_CAMKL_BRSK_BRSK2_ST	P49815	TSC2	Q8IWQ3	BRSK2	S997	L995I	995	Missense	proximal	-2	no	4.377	4.357	EPSD	CCLE	3.184	Down-regulation
CAMK_CAMKL_BRSK_BRSK2_ST	P49815	TSC2	Q8IWQ3	BRSK2	S1002	L995I	995	Missense	distal	-7	no	4.017	3.866	EPSD	CCLE	3.184	Down-regulation
CAMK_CAMKL_BRSK_BRSK2_ST	P49815	TSC2	Q8IWQ3	BRSK2	S1002	N1006S	1006	Missense	distal	4	no	4.017	3.849	EPSD	CCLE	3.184	Down-regulation
CAMK_CAMKL_BRSK_BRSK2_ST	P49815	TSC2	Q8IWQ3	BRSK2	T1462	P1458T	1458	Missense	distal	-4	no	3.574	4.015	EPSD	CCLE	3.184	Up-regulation
CAMK_CAMKL_BRSK_BRSK2_ST	Q00536	CDK16	Q8IWQ3	BRSK2	S58	A51V	51	Missense	distal	-7	no	4.691	4.704	EPSD	CCLE	3.184	Up-regulation
CAMK_CAMKL_BRSK_BRSK2_ST	Q00536	CDK16	Q8IWQ3	BRSK2	S119	D123N	123	Missense	distal	4	no	3.775	3.952	EPSD	CCLE	3.184	Up-regulation
Atypical_PIKK_DNAPK_PRKDC_ST	P14859	POU2F1	P78527	PRKDC	T21	T23P	23	Missense	proximal	2	no	12.609	13.363	EPSD	CCLE	8.283	Up-regulation
Atypical_PIKK_DNAPK_PRKDC_ST	P14859	POU2F1	P78527	PRKDC	S141	H140P	140	Missense	proximal	-1	no	11.031	11.060	EPSD;PhosphoSitePlus	CCLE	8.283	Up-regulation
Atypical_PIKK_DNAPK_PRKDC_ST	P14859	POU2F1	P78527	PRKDC	S143	H140P	140	Missense	distal	-3	no	13.593	13.587	EPSD;PhosphoSitePlus	CCLE	8.283	Down-regulation
Atypical_PIKK_DNAPK_PRKDC_ST	P14859	POU2F1	P78527	PRKDC	S147	H140P	140	Missense	distal	-7	no	10.002	9.201	EPSD;PhosphoSitePlus	CCLE	8.283	Down-regulation
Atypical_PIKK_DNAPK_PRKDC_ST	P35637	FUS	P78527	PRKDC	T7	Y14C	14	Missense	distal	7	no	13.626	12.621	EPSD;PhosphoSitePlus	CCLE	8.283	Down-regulation
Atypical_PIKK_DNAPK_PRKDC_ST	P35637	FUS	P78527	PRKDC	T11	Y14C	14	Missense	distal	3	no	13.935	13.728	EPSD;PhosphoSitePlus	CCLE	8.283	Down-regulation
Atypical_PIKK_DNAPK_PRKDC_ST	P35637	FUS	P78527	PRKDC	T19	Y14C	14	Missense	distal	-5	no	14.852	14.740	PhosphoSitePlus;EPSD	CCLE	8.283	Down-regulation
Atypical_PIKK_DNAPK_PRKDC_ST	Q96SD1	DCLRE1C	P78527	PRKDC	S553	V558G	558	Missense	distal	5	no	18.059	18.100	EPSD;PhosphoSitePlus	CCLE	8.283	Up-regulation
Atypical_PIKK_DNAPK_PRKDC_ST	Q96SD1	DCLRE1C	P78527	PRKDC	S562	V558G	558	Missense	distal	-4	no	13.528	13.909	EPSD	CCLE	8.283	Up-regulation
Atypical_PIKK_DNAPK_PRKDC_ST	P23508	MCC	P78527	PRKDC	S118	E123K	123	Missense	distal	5	no	14.462	14.229	EPSD;PhosphoSitePlus	CCLE	8.283	Down-regulation
Atypical_PIKK_DNAPK_PRKDC_ST	P23508	MCC	P78527	PRKDC	S120	E123K	123	Missense	distal	3	no	12.008	11.450	PhosphoSitePlus;EPSD	CCLE	8.283	Down-regulation
Atypical_PIKK_DNAPK_PRKDC_ST	P23508	MCC	P78527	PRKDC	S182	C181S	181	Missense	proximal	-1	no	9.659	10.340	EPSD	CCLE	8.283	Up-regulation
Atypical_PIKK_DNAPK_PRKDC_ST	P23508	MCC	P78527	PRKDC	S182	K177R	177	Missense	distal	-5	no	9.659	9.219	EPSD	CCLE	8.283	Down-regulation
Atypical_PIKK_DNAPK_PRKDC_ST	P23508	MCC	P78527	PRKDC	S184	C181S	181	Missense	distal	-3	no	9.489	9.725	EPSD	CCLE	8.283	Up-regulation
Atypical_PIKK_DNAPK_PRKDC_ST	P23508	MCC	P78527	PRKDC	S184	K177R	177	Missense	distal	-7	no	9.489	9.031	EPSD	CCLE	8.283	Down-regulation
Atypical_PIKK_DNAPK_PRKDC_ST	P23508	MCC	P78527	PRKDC	S485	A480V	480	Missense	distal	-5	no	8.603	8.111	EPSD	CCLE	8.283	Loss
Atypical_PIKK_DNAPK_PRKDC_ST	P23508	MCC	P78527	PRKDC	S706	E709K	709	Missense	distal	3	no	8.856	8.298	EPSD	CCLE	8.283	Down-regulation
Atypical_PIKK_DNAPK_PRKDC_ST	Q14191	WRN	P78527	PRKDC	S462	D460G	460	Missense	proximal	-2	no	9.037	9.154	EPSD	CCLE	8.283	Up-regulation
Atypical_PIKK_DNAPK_PRKDC_ST	Q14191	WRN	P78527	PRKDC	S467	D460G	460	Missense	distal	-7	no	9.488	9.111	EPSD;PhosphoSitePlus	CCLE	8.283	Down-regulation
Atypical_PIKK_DNAPK_PRKDC_ST	P04637	TP53	P78527	PRKDC	S33	E28Q	28	Missense	distal	-5	no	9.126	9.069	EPSD	CCLE	8.283	Down-regulation
Atypical_PIKK_DNAPK_PRKDC_ST	Q9UGP5	POLL	P78527	PRKDC	S152	I153V	153	Missense	proximal	1	no	3.142	10.058	EPSD	CCLE	8.283	Gain
Atypical_PIKK_DNAPK_PRKDC_ST	P17936	IGFBP3	P78527	PRKDC	T14	A12T	12	Missense	proximal	-2	no	8.456	8.536	EPSD	CCLE	8.283	Up-regulation
Atypical_PIKK_DNAPK_PRKDC_ST	P17936	IGFBP3	P78527	PRKDC	S183	D189Y	189	Missense	distal	6	no	12.628	12.631	PhosphoSitePlus	CCLE	8.283	Up-regulation
Atypical_PIKK_DNAPK_PRKDC_ST	P17936	IGFBP3	P78527	PRKDC	S183	H179N	179	Missense	distal	-4	no	12.628	12.749	PhosphoSitePlus	CCLE	8.283	Up-regulation
Atypical_PIKK_DNAPK_PRKDC_ST	P17936	IGFBP3	P78527	PRKDC	S192	D189Y	189	Missense	distal	-3	no	12.569	12.799	EPSD	CCLE	8.283	Up-regulation
Atypical_PIKK_DNAPK_PRKDC_ST	Q9H9Q4	NHEJ1	P78527	PRKDC	S55	S52I	52	Missense	distal	-3	no	10.966	10.459	EPSD;PhosphoSitePlus	CCLE	8.283	Down-regulation
Atypical_PIKK_DNAPK_PRKDC_ST	P07900	HSP90AA1	P78527	PRKDC	S252	E248K	248	Missense	distal	-4	no	9.472	9.216	EPSD	CCLE	8.283	Down-regulation
Atypical_PIKK_DNAPK_PRKDC_ST	P46527	CDKN1B	P78527	PRKDC	S10	S12I	12	Missense	proximal	2	no	9.159	6.296	EPSD	CCLE	8.283	Loss
Atypical_PIKK_DNAPK_PRKDC_ST	P46527	CDKN1B	P78527	PRKDC	S12	S12I	12	Missense	central	0	yes	10.753	0.000	EPSD	CCLE	8.283	Loss
Atypical_PIKK_DNAPK_PRKDC_ST	P19838	NFKB1	P78527	PRKDC	S371	G377D	377	Missense	distal	6	no	8.314	8.333	EPSD	CCLE	8.283	Up-regulation
Atypical_PIKK_DNAPK_PRKDC_ST	P19838	NFKB1	P78527	PRKDC	S899	S893N	893	Missense	distal	-6	no	12.719	12.664	EPSD	CCLE	8.283	Down-regulation
Atypical_PIKK_DNAPK_PRKDC_ST	Q00839	HNRNPU	P78527	PRKDC	S799	G801R	801	Missense	proximal	2	no	13.660	13.160	EPSD	CCLE	8.283	Down-regulation
Atypical_PIKK_DNAPK_PRKDC_ST	Q00839	HNRNPU	P78527	PRKDC	S799	N797D	797	Missense	proximal	-2	no	13.660	13.637	EPSD	CCLE	8.283	Down-regulation
Atypical_PIKK_DNAPK_PRKDC_ST	P24928	POLR2A	P78527	PRKDC	S27	E30K	30	Missense	distal	3	no	11.215	10.657	EPSD	CCLE	8.283	Down-regulation
Atypical_PIKK_DNAPK_PRKDC_ST	P24928	POLR2A	P78527	PRKDC	S1574	P1567L	1567	Missense	distal	-7	no	9.448	9.631	EPSD	CCLE	8.283	Up-regulation
Atypical_PIKK_DNAPK_PRKDC_ST	P24928	POLR2A	P78527	PRKDC	S1616	S1616Y	1616	Missense	central	0	yes	8.905	0.000	PhosphoSitePlus;EPSD	CCLE	8.283	Loss
Atypical_PIKK_DNAPK_PRKDC_ST	P24928	POLR2A	P78527	PRKDC	S1619	S1616Y	1616	Missense	distal	-3	no	8.764	9.003	EPSD	CCLE	8.283	Up-regulation
Atypical_PIKK_DNAPK_PRKDC_ST	P24928	POLR2A	P78527	PRKDC	S1621	S1616Y	1616	Missense	distal	-5	no	9.489	9.142	EPSD;PhosphoSitePlus	CCLE	8.283	Down-regulation
Atypical_PIKK_DNAPK_PRKDC_ST	P24928	POLR2A	P78527	PRKDC	S1654	T1660P	1660	Missense	distal	6	no	8.448	8.462	EPSD	CCLE	8.283	Up-regulation
Atypical_PIKK_DNAPK_PRKDC_ST	P24928	POLR2A	P78527	PRKDC	S1656	T1660P	1660	Missense	distal	4	no	10.099	10.115	EPSD	CCLE	8.283	Up-regulation
Atypical_PIKK_DNAPK_PRKDC_ST	P24928	POLR2A	P78527	PRKDC	S1661	T1660P	1660	Missense	proximal	-1	no	8.465	9.290	EPSD	CCLE	8.283	Up-regulation
Atypical_PIKK_DNAPK_PRKDC_ST	P24928	POLR2A	P78527	PRKDC	S1663	T1660P	1660	Missense	distal	-3	no	9.778	10.040	EPSD	CCLE	8.283	Up-regulation
Atypical_PIKK_DNAPK_PRKDC_ST	P24928	POLR2A	P78527	PRKDC	S1710	Y1713S	1713	Missense	distal	3	no	8.429	8.584	EPSD	CCLE	8.283	Up-regulation
Atypical_PIKK_DNAPK_PRKDC_ST	P24928	POLR2A	P78527	PRKDC	S1712	Y1713S	1713	Missense	proximal	1	no	9.950	5.110	EPSD	CCLE	8.283	Loss
Atypical_PIKK_DNAPK_PRKDC_ST	P24928	POLR2A	P78527	PRKDC	S1717	Y1713S	1713	Missense	distal	-4	no	8.356	8.621	EPSD	CCLE	8.283	Up-regulation
Atypical_PIKK_DNAPK_PRKDC_ST	P24928	POLR2A	P78527	PRKDC	S1719	Y1713S	1713	Missense	distal	-6	no	10.260	10.655	EPSD	CCLE	8.283	Up-regulation
Atypical_PIKK_DNAPK_PRKDC_ST	P24928	POLR2A	P78527	PRKDC	S1766	Y1762H	1762	Missense	distal	-4	no	8.171	8.293	EPSD	CCLE	8.283	Gain
Atypical_PIKK_DNAPK_PRKDC_ST	P24928	POLR2A	P78527	PRKDC	S1917	P1914L	1914	Missense	distal	-3	no	8.327	8.127	EPSD	CCLE	8.283	Loss
Atypical_PIKK_DNAPK_PRKDC_ST	P24928	POLR2A	P78527	PRKDC	T1943	S1944Y	1944	Missense	proximal	1	no	4.089	8.930	EPSD	CCLE	8.283	Gain
Atypical_PIKK_DNAPK_PRKDC_ST	P24928	POLR2A	P78527	PRKDC	S1948	S1941F	1941	Missense	distal	-7	no	8.370	7.825	EPSD	CCLE	8.283	Loss
Atypical_PIKK_DNAPK_PRKDC_ST	P24928	POLR2A	P78527	PRKDC	S1948	S1944Y	1944	Missense	distal	-4	no	8.370	8.105	EPSD	CCLE	8.283	Loss
Atypical_PIKK_DNAPK_PRKDC_ST	P24928	POLR2A	P78527	PRKDC	S1948	P1952A	1952	Missense	distal	4	no	8.370	8.415	EPSD	CCLE	8.283	Up-regulation
Atypical_PIKK_DNAPK_PRKDC_ST	P24928	POLR2A	P78527	PRKDC	S1951	S1944Y	1944	Missense	distal	-7	no	8.952	8.524	EPSD	CCLE	8.283	Down-regulation
Atypical_PIKK_DNAPK_PRKDC_ST	P24928	POLR2A	P78527	PRKDC	S1951	P1952A	1952	Missense	proximal	1	no	8.952	8.128	EPSD	CCLE	8.283	Loss
Atypical_PIKK_DNAPK_PRKDC_ST	P24928	POLR2A	P78527	PRKDC	S1955	P1952A	1952	Missense	distal	-3	no	8.902	8.700	EPSD	CCLE	8.283	Down-regulation
Atypical_PIKK_DNAPK_PRKDC_ST	Q15648	MED1	P78527	PRKDC	S387	R386L	386	Missense	proximal	-1	no	9.550	10.330	EPSD	CCLE	8.283	Up-regulation
Atypical_PIKK_DNAPK_PRKDC_ST	Q15648	MED1	P78527	PRKDC	S874	E881G	881	Missense	distal	7	no	13.147	12.420	EPSD	CCLE	8.283	Down-regulation
Atypical_PIKK_DNAPK_PRKDC_ST	Q15648	MED1	P78527	PRKDC	S887	E881G	881	Missense	distal	-6	no	12.552	12.217	EPSD	CCLE	8.283	Down-regulation
Atypical_PIKK_DNAPK_PRKDC_ST	Q15648	MED1	P78527	PRKDC	S1417	G1414R	1414	Missense	distal	-3	no	8.472	8.377	EPSD	CCLE	8.283	Down-regulation
Atypical_PIKK_DNAPK_PRKDC_ST	Q15648	MED1	P78527	PRKDC	T1457	T1457P	1457	Missense	central	0	yes	10.753	0.000	PhosphoSitePlus	CCLE	8.283	Loss
Atypical_PIKK_DNAPK_PRKDC_ST	P11831	SRF	P78527	PRKDC	S16	S21N	21	Missense	distal	5	no	8.328	8.252	EPSD	CCLE	8.283	Loss
Atypical_PIKK_DNAPK_PRKDC_ST	P11831	SRF	P78527	PRKDC	S21	S21N	21	Missense	central	0	yes	8.920	0.000	EPSD	CCLE	8.283	Loss
Atypical_PIKK_DNAPK_PRKDC_ST	P11831	SRF	P78527	PRKDC	T67	G73R	73	Missense	distal	6	no	8.322	8.312	EPSD	CCLE	8.283	Down-regulation
Atypical_PIKK_DNAPK_PRKDC_ST	P11831	SRF	P78527	PRKDC	S224	R227H	227	Missense	distal	3	no	9.633	9.940	EPSD	CCLE	8.283	Up-regulation
Atypical_PIKK_DNAPK_PRKDC_ST	O96017	CHEK2	P78527	PRKDC	S357	D361G	361	Missense	distal	4	no	11.047	11.044	EPSD	CCLE	8.283	Down-regulation
Atypical_PIKK_DNAPK_PRKDC_ST	O96017	CHEK2	P78527	PRKDC	T432	S435L	435	Missense	distal	3	no	9.582	9.201	EPSD	CCLE	8.283	Down-regulation
Atypical_PIKK_DNAPK_PRKDC_ST	P42575	CASP2	P78527	PRKDC	S139	D135G	135	Missense	distal	-4	no	9.692	9.305	PhosphoSitePlus	CCLE	8.283	Down-regulation
Atypical_PIKK_DNAPK_PRKDC_ST	Q9BQ15	NABP2	P78527	PRKDC	T117	Y115H	115	Missense	proximal	-2	no	13.888	13.932	EPSD	CCLE	8.283	Up-regulation
Atypical_PIKK_DNAPK_PRKDC_ST	P08670	VIM	P78527	PRKDC	S10	S8P	8	Missense	proximal	-2	no	9.148	9.173	EPSD	CCLE	8.283	Up-regulation
Atypical_PIKK_DNAPK_PRKDC_ST	P08670	VIM	P78527	PRKDC	T202	N201S	201	Missense	proximal	-1	no	9.911	9.902	EPSD	CCLE	8.283	Down-regulation
Atypical_PIKK_DNAPK_PRKDC_ST	P08670	VIM	P78527	PRKDC	S412	N417T	417	Missense	distal	5	no	8.758	8.690	EPSD	CCLE	8.283	Down-regulation
Atypical_PIKK_DNAPK_PRKDC_ST	P18887	XRCC1	P78527	PRKDC	S210	P206L	206	Missense	distal	-4	no	11.850	11.806	EPSD	CCLE	8.283	Down-regulation
Atypical_PIKK_DNAPK_PRKDC_ST	P18887	XRCC1	P78527	PRKDC	T281	P276S	276	Missense	distal	-5	no	8.237	8.608	EPSD	CCLE	8.283	Gain
Atypical_PIKK_DNAPK_PRKDC_ST	P18887	XRCC1	P78527	PRKDC	T440	S446R	446	Missense	distal	6	no	13.840	13.820	EPSD	CCLE	8.283	Down-regulation
Atypical_PIKK_DNAPK_PRKDC_ST	P18887	XRCC1	P78527	PRKDC	S447	P448A	448	Missense	proximal	1	no	9.769	8.945	EPSD	CCLE	8.283	Down-regulation
Atypical_PIKK_DNAPK_PRKDC_ST	P18887	XRCC1	P78527	PRKDC	S447	S446R	446	Missense	proximal	-1	no	9.769	9.027	EPSD	CCLE	8.283	Down-regulation
Atypical_PIKK_DNAPK_PRKDC_ST	P18887	XRCC1	P78527	PRKDC	T453	P448A	448	Missense	distal	-5	no	11.500	11.736	EPSD	CCLE	8.283	Up-regulation
Atypical_PIKK_DNAPK_PRKDC_ST	P18887	XRCC1	P78527	PRKDC	T453	S446R	446	Missense	distal	-7	no	11.500	10.834	EPSD	CCLE	8.283	Down-regulation
Atypical_PIKK_DNAPK_PRKDC_ST	Q8IZL8	PELP1	P78527	PRKDC	S7	G12C	12	Missense	distal	5	no	8.492	8.408	EPSD	CCLE	8.283	Down-regulation
Atypical_PIKK_DNAPK_PRKDC_ST	Q8IZL8	PELP1	P78527	PRKDC	S7	G8V	8	Missense	proximal	1	no	8.492	9.200	EPSD	CCLE	8.283	Up-regulation
Atypical_PIKK_DNAPK_PRKDC_ST	Q8IZL8	PELP1	P78527	PRKDC	S10	G12C	12	Missense	proximal	2	no	10.189	9.814	EPSD	CCLE	8.283	Down-regulation
Atypical_PIKK_DNAPK_PRKDC_ST	Q8IZL8	PELP1	P78527	PRKDC	S10	G8V	8	Missense	proximal	-2	no	10.189	10.229	EPSD	CCLE	8.283	Up-regulation
Atypical_PIKK_DNAPK_PRKDC_ST	Q8IZL8	PELP1	P78527	PRKDC	S13	G12C	12	Missense	proximal	-1	no	8.997	8.578	EPSD	CCLE	8.283	Down-regulation
Atypical_PIKK_DNAPK_PRKDC_ST	Q8IZL8	PELP1	P78527	PRKDC	S13	G8V	8	Missense	distal	-5	no	8.997	8.670	EPSD	CCLE	8.283	Down-regulation
Atypical_PIKK_DNAPK_PRKDC_ST	Q8IZL8	PELP1	P78527	PRKDC	S251	G253C	253	Missense	proximal	2	no	13.258	12.883	EPSD	CCLE	8.283	Down-regulation
Atypical_PIKK_DNAPK_PRKDC_ST	Q8IZL8	PELP1	P78527	PRKDC	T647	P654T	654	Missense	distal	7	no	9.452	8.732	EPSD	CCLE	8.283	Down-regulation
Atypical_PIKK_DNAPK_PRKDC_ST	Q8IZL8	PELP1	P78527	PRKDC	T647	P653R	653	Missense	distal	6	no	9.452	9.423	EPSD	CCLE	8.283	Down-regulation
Atypical_PIKK_DNAPK_PRKDC_ST	Q8IZL8	PELP1	P78527	PRKDC	T981	P979H	979	Missense	proximal	-2	no	8.457	8.427	EPSD	CCLE	8.283	Down-regulation
Atypical_PIKK_DNAPK_PRKDC_ST	Q8IZL8	PELP1	P78527	PRKDC	T981	G975D	975	Missense	distal	-6	no	8.457	8.641	EPSD	CCLE	8.283	Up-regulation
Atypical_PIKK_DNAPK_PRKDC_ST	P55895	RAG2	P78527	PRKDC	S365	D371N	371	Missense	distal	6	no	13.045	13.041	PhosphoSitePlus	CCLE	8.283	Down-regulation
Atypical_PIKK_DNAPK_PRKDC_ST	P11387	TOP1	P78527	PRKDC	S112	Q115R	115	Missense	distal	3	no	11.151	10.536	EPSD	CCLE	8.283	Down-regulation
Atypical_PIKK_DNAPK_PRKDC_ST	P11387	TOP1	P78527	PRKDC	T303	M305I	305	Missense	proximal	2	no	11.969	10.692	EPSD	CCLE	8.283	Down-regulation
AGC_PKN_PKN1_ST	P10636	MAPT	Q16512	PKN1	S64	A66V	66	Missense	proximal	2	no	61.972	60.544	EPSD	CCLE	59.390	Down-regulation
AGC_PKN_PKN1_ST	P10636	MAPT	Q16512	PKN1	T167	E161Q	161	Missense	distal	-6	no	80.887	81.798	EPSD	CCLE	59.390	Up-regulation
AGC_PKN_PKN1_ST	P10636	MAPT	Q16512	PKN1	T167	P170F	170	Missense	distal	3	no	80.887	81.821	EPSD	CCLE	59.390	Up-regulation
AGC_PKN_PKN1_ST	P10636	MAPT	Q16512	PKN1	T167	G174A	174	Missense	distal	7	no	80.887	80.661	EPSD	CCLE	59.390	Down-regulation
AGC_PKN_PKN1_ST	P10636	MAPT	Q16512	PKN1	S171	P170F	170	Missense	proximal	-1	no	79.050	78.686	EPSD	CCLE	59.390	Down-regulation
AGC_PKN_PKN1_ST	P10636	MAPT	Q16512	PKN1	S171	G174A	174	Missense	distal	3	no	79.050	78.119	EPSD	CCLE	59.390	Down-regulation
AGC_PKN_PKN1_ST	P10636	MAPT	Q16512	PKN1	S214	D221Y	221	Missense	distal	7	no	64.058	63.647	EPSD;PhosphoSitePlus	CCLE	59.390	Down-regulation
AGC_PKN_PKN1_ST	P10636	MAPT	Q16512	PKN1	S400	K405R	405	Missense	distal	5	no	76.145	76.533	EPSD	CCLE	59.390	Up-regulation
AGC_PKN_PKN1_ST	P10636	MAPT	Q16512	PKN1	T403	K405R	405	Missense	proximal	2	no	65.263	66.565	EPSD	CCLE	59.390	Up-regulation
AGC_PKN_PKN1_ST	P10636	MAPT	Q16512	PKN1	S515	R511H	511	Missense	distal	-4	no	68.334	66.916	EPSD	CCLE	59.390	Down-regulation
AGC_PKN_PKN1_ST	P10636	MAPT	Q16512	PKN1	S515	G518S	518	Missense	distal	3	no	68.334	67.561	EPSD	CCLE	59.390	Down-regulation
AGC_PKN_PKN1_ST	P10636	MAPT	Q16512	PKN1	S525	G518S	518	Missense	distal	-7	no	66.199	66.275	EPSD	CCLE	59.390	Up-regulation
AGC_PKN_PKN1_ST	P10636	MAPT	Q16512	PKN1	S525	R526L	526	Missense	proximal	1	no	66.199	62.889	EPSD	CCLE	59.390	Down-regulation
AGC_PKN_PKN1_ST	P10636	MAPT	Q16512	PKN1	T529	R526L	526	Missense	distal	-3	no	60.583	43.309	EPSD	CCLE	59.390	Loss
AGC_PKN_PKN1_ST	P10636	MAPT	Q16512	PKN1	S531	R526L	526	Missense	distal	-5	no	86.612	86.315	EPSD	CCLE	59.390	Down-regulation
AGC_PKN_PKN1_ST	P10636	MAPT	Q16512	PKN1	S558	R559H	559	Missense	proximal	1	no	69.690	61.107	EPSD	CCLE	59.390	Down-regulation
AGC_PKN_PKN1_ST	P10636	MAPT	Q16512	PKN1	T562	R559H	559	Missense	distal	-3	no	75.943	54.881	EPSD	CCLE	59.390	Loss
AGC_PKN_PKN1_ST	P10636	MAPT	Q16512	PKN1	S575	K574N	574	Missense	proximal	-1	no	81.707	84.709	EPSD	CCLE	59.390	Up-regulation
AGC_PKN_PKN1_ST	P10636	MAPT	Q16512	PKN1	S637	D631E	631	Missense	distal	-6	no	88.507	87.631	EPSD	CCLE	59.390	Down-regulation
AGC_PKN_PKN1_ST	P10636	MAPT	Q16512	PKN1	T703	G706V	706	Missense	distal	3	no	61.806	60.516	EPSD	CCLE	59.390	Down-regulation
AGC_PKN_PKN1_ST	P10636	MAPT	Q16512	PKN1	S726	S721C	721	Missense	distal	-5	no	69.247	68.602	EPSD	CCLE	59.390	Down-regulation
AGC_PKN_PKN1_ST	P10636	MAPT	Q16512	PKN1	S726	H724R	724	Missense	proximal	-2	no	69.247	73.870	EPSD	CCLE	59.390	Up-regulation
AGC_PKN_PKN1_ST	Q9UKV0	HDAC9	Q16512	PKN1	T183	H182R	182	Missense	proximal	-1	no	60.745	58.103	EPSD	CCLE	59.390	Loss
AGC_PKN_PKN1_ST	Q9UKV0	HDAC9	Q16512	PKN1	S184	H182R	182	Missense	proximal	-2	no	56.694	61.317	EPSD	CCLE	59.390	Gain
AGC_PKN_PKN1_ST	Q9UKV0	HDAC9	Q16512	PKN1	S240	A235T	235	Missense	distal	-5	no	73.557	73.531	EPSD	CCLE	59.390	Down-regulation
AGC_PKN_PKN1_ST	Q9UKV0	HDAC9	Q16512	PKN1	S253	N249I	249	Missense	distal	-4	no	96.882	94.049	PhosphoSitePlus	CCLE	59.390	Down-regulation
AGC_PKN_PKN1_ST	Q9UKV0	HDAC9	Q16512	PKN1	S253	V250L	250	Missense	distal	-3	no	96.882	103.595	PhosphoSitePlus	CCLE	59.390	Up-regulation
AGC_PKN_PKN1_ST	Q9UKV0	HDAC9	Q16512	PKN1	S253	M258V	258	Missense	distal	5	no	96.882	96.857	PhosphoSitePlus	CCLE	59.390	Down-regulation
AGC_PKN_PKN1_ST	Q9UKV0	HDAC9	Q16512	PKN1	S611	R608S	608	Missense	distal	-3	no	64.406	49.576	EPSD	CCLE	59.390	Loss
AGC_PKN_PKN1_ST	Q9UQL6	HDAC5	Q16512	PKN1	T479	T479I	479	Missense	central	0	yes	62.623	0.000	EPSD	CCLE	59.390	Loss
AGC_PKN_PKN1_ST	Q9UQL6	HDAC5	Q16512	PKN1	T650	A644V	644	Missense	distal	-6	no	68.199	68.935	EPSD	CCLE	59.390	Up-regulation
AGC_PKN_PKN1_ST	Q9UQL6	HDAC5	Q16512	PKN1	S713	R710G	710	Missense	distal	-3	no	59.671	7.788	EPSD	CCLE	59.390	Loss
AGC_PKN_PKN1_ST	O15553	MEFV	Q16512	PKN1	S179	G184S	184	Missense	distal	5	no	69.033	69.425	EPSD	CCLE	59.390	Up-regulation
AGC_PKN_PKN1_ST	P30622	CLIP1	Q16512	PKN1	S306	T302P	302	Missense	distal	-4	no	63.911	64.426	EPSD	CCLE	59.390	Up-regulation
AGC_PKN_PKN1_ST	P30622	CLIP1	Q16512	PKN1	S312	L316V	316	Missense	distal	4	no	88.259	83.228	PhosphoSitePlus	CCLE	59.390	Down-regulation
AGC_PKN_PKN1_ST	P30622	CLIP1	Q16512	PKN1	S320	L316V	316	Missense	distal	-4	no	68.123	66.936	EPSD	CCLE	59.390	Down-regulation
AGC_PKN_PKN1_ST	P30622	CLIP1	Q16512	PKN1	S784	S783R	783	Missense	proximal	-1	no	63.519	61.148	EPSD	CCLE	59.390	Down-regulation
AGC_PKN_PKN1_ST	Q16512	PKN1	Q16512	PKN1	T64	G71C	71	Missense	distal	7	no	81.694	81.252	EPSD	CCLE	59.390	Down-regulation
AGC_PKN_PKN1_ST	Q16512	PKN1	Q16512	PKN1	S81	L76P	76	Missense	distal	-5	no	72.999	71.889	EPSD	CCLE	59.390	Down-regulation
AGC_PKN_PKN1_ST	Q16512	PKN1	Q16512	PKN1	S81	R82C	82	Missense	proximal	1	no	72.999	71.283	EPSD	CCLE	59.390	Down-regulation
AGC_PKN_PKN1_ST	Q16512	PKN1	Q16512	PKN1	S126	R127L	127	Missense	proximal	1	no	68.591	65.281	EPSD	CCLE	59.390	Down-regulation
AGC_PKN_PKN1_ST	Q16512	PKN1	Q16512	PKN1	S240	A244V	244	Missense	distal	4	no	62.490	56.264	EPSD	CCLE	59.390	Loss
AGC_PKN_PKN1_ST	Q16512	PKN1	Q16512	PKN1	S374	L368F	368	Missense	distal	-6	no	88.259	89.337	EPSD	CCLE	59.390	Up-regulation
AGC_PKN_PKN1_ST	Q16512	PKN1	Q16512	PKN1	T545	A542V	542	Missense	distal	-3	no	71.987	63.053	EPSD	CCLE	59.390	Down-regulation
AGC_PKN_PKN1_ST	Q16512	PKN1	Q16512	PKN1	T596	P597Q	597	Missense	proximal	1	no	74.034	68.540	EPSD	CCLE	59.390	Down-regulation
AGC_PKN_PKN1_ST	Q16512	PKN1	Q16512	PKN1	T774	P779S	779	Missense	distal	5	no	95.095	95.297	PhosphoSitePlus	CCLE	59.390	Up-regulation
AGC_PKN_PKN1_ST	Q16512	PKN1	Q16512	PKN1	T899	P893A	893	Missense	distal	-6	no	64.664	64.018	EPSD	CCLE	59.390	Down-regulation
AGC_PKN_PKN1_ST	Q16512	PKN1	Q16512	PKN1	T899	R898H	898	Missense	proximal	-1	no	64.664	67.306	EPSD	CCLE	59.390	Up-regulation
Atypical_PIKK_SMG1_SMG1_ST	Q92900	UPF1	Q96Q15	SMG1	S42	Q45H	45	Missense	distal	3	no	2.743	2.737	EPSD	CCLE	1.372	Down-regulation
Atypical_PIKK_SMG1_SMG1_ST	Q92900	UPF1	Q96Q15	SMG1	S42	G49D	49	Missense	distal	7	no	2.743	2.772	EPSD	CCLE	1.372	Up-regulation
Atypical_PIKK_SMG1_SMG1_ST	Q92900	UPF1	Q96Q15	SMG1	T44	Q45H	45	Missense	proximal	1	no	3.393	0.538	EPSD	CCLE	1.372	Loss
Atypical_PIKK_SMG1_SMG1_ST	Q92900	UPF1	Q96Q15	SMG1	T44	G49D	49	Missense	distal	5	no	3.393	3.372	EPSD	CCLE	1.372	Down-regulation
Atypical_PIKK_SMG1_SMG1_ST	Q92900	UPF1	Q96Q15	SMG1	S599	E597K	597	Missense	proximal	-2	no	1.949	1.950	EPSD	CCLE	1.372	Up-regulation
Atypical_PIKK_SMG1_SMG1_ST	Q92900	UPF1	Q96Q15	SMG1	S599	R605W	605	Missense	distal	6	no	1.949	1.948	EPSD	CCLE	1.372	Down-regulation
Atypical_PIKK_SMG1_SMG1_ST	Q92900	UPF1	Q96Q15	SMG1	S1084	S1089A	1089	Missense	distal	5	no	6.300	6.302	EPSD;PhosphoSitePlus	CCLE	1.372	Up-regulation
Atypical_PIKK_SMG1_SMG1_ST	Q92900	UPF1	Q96Q15	SMG1	S1089	S1089A	1089	Missense	central	0	yes	5.994	0.000	EPSD;PhosphoSitePlus	CCLE	1.372	Loss
Atypical_PIKK_SMG1_SMG1_ST	Q92900	UPF1	Q96Q15	SMG1	S1107	G1114E	1114	Missense	distal	7	no	6.017	6.077	EPSD;PhosphoSitePlus	CCLE	1.372	Up-regulation
Atypical_PIKK_SMG1_SMG1_ST	Q92900	UPF1	Q96Q15	SMG1	S1127	S1127A	1127	Missense	central	0	yes	4.310	0.000	EPSD;PhosphoSitePlus	CCLE	1.372	Loss
Atypical_PIKK_SMG1_SMG1_ST	P04637	TP53	Q96Q15	SMG1	S33	E28Q	28	Missense	distal	-5	no	1.652	1.687	EPSD	CCLE	1.372	Up-regulation
STE_STE11_ASK_MAP3K6_ST	P45983	MAPK8	O95382	MAP3K6	T19	I15T	15	Missense	distal	-4	no	4.888	4.883	EPSD	CCLE	1.891	Down-regulation
STE_STE11_ASK_MAP3K6_ST	P45983	MAPK8	O95382	MAP3K6	T19	K24T	24	Missense	distal	5	no	4.888	5.435	EPSD	CCLE	1.891	Up-regulation
STE_STE11_ASK_MAP3K6_ST	P45983	MAPK8	O95382	MAP3K6	T183	T188N	188	Missense	distal	5	no	15.332	15.059	PhosphoSitePlus;EPSD	CCLE	1.891	Down-regulation
STE_STE11_ASK_MAP3K6_ST	P45983	MAPK8	O95382	MAP3K6	T183	T188I	188	Missense	distal	5	no	15.332	14.825	PhosphoSitePlus;EPSD	CCLE	1.891	Down-regulation
STE_STE11_ASK_MAP3K6_ST	P45983	MAPK8	O95382	MAP3K6	T188	T188N	188	Missense	central	0	yes	1.928	0.000	EPSD	CCLE	1.891	Loss
STE_STE11_ASK_MAP3K6_ST	P45983	MAPK8	O95382	MAP3K6	T188	T188I	188	Missense	central	0	yes	1.928	0.000	EPSD	CCLE	1.891	Loss
STE_STE11_ASK_MAP3K6_ST	O95382	MAP3K6	O95382	MAP3K6	S935	A930T	930	Missense	distal	-5	no	1.312	3.014	EPSD	CCLE	1.891	Gain
CAMK_DAPK_DAPK_DAPK1_ST	P53355	DAPK1	P53355	DAPK1	S57	S52N	52	Missense	distal	-5	no	10.150	10.050	EPSD	CCLE	8.849	Down-regulation
CAMK_DAPK_DAPK_DAPK1_ST	P53355	DAPK1	P53355	DAPK1	S319	F322Y	322	Missense	distal	3	no	11.303	10.697	EPSD	CCLE	8.849	Down-regulation
CAMK_DAPK_DAPK_DAPK1_ST	P53355	DAPK1	P53355	DAPK1	S762	V758L	758	Missense	distal	-4	no	9.106	9.126	EPSD	CCLE	8.849	Up-regulation
CAMK_DAPK_DAPK_DAPK1_ST	O95786	DDX58	P53355	DAPK1	S654	N650D	650	Missense	distal	-4	no	16.697	16.625	PhosphoSitePlus;EPSD	CCLE	8.849	Down-regulation
CAMK_DAPK_DAPK_DAPK1_ST	O95786	DDX58	P53355	DAPK1	T770	A774P	774	Missense	distal	4	no	15.226	15.395	EPSD;PhosphoSitePlus	CCLE	8.849	Up-regulation
CAMK_DAPK_DAPK_DAPK1_ST	Q96RR4	CAMKK2	P53355	DAPK1	T145	S148F	148	Missense	distal	3	no	9.938	11.365	EPSD	CCLE	8.849	Up-regulation
CAMK_DAPK_DAPK_DAPK1_ST	Q96RR4	CAMKK2	P53355	DAPK1	T350	P351S	351	Missense	proximal	1	no	9.990	9.063	EPSD	CCLE	8.849	Down-regulation
CAMK_DAPK_DAPK_DAPK1_ST	Q96RR4	CAMKK2	P53355	DAPK1	T522	S527F	527	Missense	distal	5	no	9.295	9.317	EPSD	CCLE	8.849	Up-regulation
CAMK_DAPK_DAPK_DAPK1_ST	P40429	RPL13A	P53355	DAPK1	S67	N63S	63	Missense	distal	-4	no	10.735	10.750	EPSD	CCLE	8.849	Up-regulation
CAMK_DAPK_DAPK_DAPK1_ST	P40429	RPL13A	P53355	DAPK1	S77	R82Q	82	Missense	distal	5	no	16.021	16.654	PhosphoSitePlus	CCLE	8.849	Up-regulation
CAMK_DAPK_DAPK_DAPK1_ST	Q14457	BECN1	P53355	DAPK1	S90	S93N	93	Missense	distal	3	no	8.647	10.032	EPSD	CCLE	8.849	Gain
CAMK_DAPK_DAPK_DAPK1_ST	Q14457	BECN1	P53355	DAPK1	T91	S93N	93	Missense	proximal	2	no	10.617	10.888	EPSD	CCLE	8.849	Up-regulation
CAMK_DAPK_DAPK_DAPK1_ST	Q14457	BECN1	P53355	DAPK1	S96	S93N	93	Missense	distal	-3	no	9.141	8.713	EPSD	CCLE	8.849	Loss
CAMK_DAPK_DAPK_DAPK1_ST	Q14457	BECN1	P53355	DAPK1	T98	S93N	93	Missense	distal	-5	no	9.650	9.549	EPSD	CCLE	8.849	Down-regulation
CAMK_DAPK_DAPK_DAPK1_ST	P25205	MCM3	P53355	DAPK1	S160	V166M	166	Missense	distal	6	no	15.355	15.978	PhosphoSitePlus	CCLE	8.849	Up-regulation
CAMK_DAPK_DAPK_DAPK1_ST	P25205	MCM3	P53355	DAPK1	S373	R371Q	371	Missense	proximal	-2	no	9.426	7.265	EPSD	CCLE	8.849	Loss
CAMK_DAPK_DAPK_DAPK1_ST	P25205	MCM3	P53355	DAPK1	T620	R623P	623	Missense	distal	3	no	9.860	10.280	EPSD	CCLE	8.849	Up-regulation
CAMK_DAPK_DAPK_DAPK1_ST	P25205	MCM3	P53355	DAPK1	T674	S681T	681	Missense	distal	7	no	9.219	8.090	EPSD	CCLE	8.849	Loss
CAMK_DAPK_DAPK_DAPK1_ST	P25205	MCM3	P53355	DAPK1	T674	R667P	667	Missense	distal	-7	no	9.219	10.797	EPSD	CCLE	8.849	Up-regulation
CAMK_DAPK_DAPK_DAPK1_ST	P09493	TPM1	P53355	DAPK1	T108	Q111H	111	Missense	distal	3	no	10.333	9.825	EPSD	CCLE	8.849	Down-regulation
CAMK_DAPK_DAPK_DAPK1_ST	Q13224	GRIN2B	P53355	DAPK1	S770	G763R	763	Missense	distal	-7	no	9.388	8.904	EPSD	CCLE	8.849	Down-regulation
CAMK_DAPK_DAPK_DAPK1_ST	Q13224	GRIN2B	P53355	DAPK1	S865	Y869N	869	Missense	distal	4	no	9.141	8.964	EPSD	CCLE	8.849	Down-regulation
CAMK_DAPK_DAPK_DAPK1_ST	Q13224	GRIN2B	P53355	DAPK1	S865	S863T	863	Missense	proximal	-2	no	9.141	7.978	EPSD	CCLE	8.849	Loss
CAMK_DAPK_DAPK_DAPK1_ST	Q13224	GRIN2B	P53355	DAPK1	S1166	S1159G	1159	Missense	distal	-7	no	9.263	9.281	EPSD	CCLE	8.849	Up-regulation
CAMK_DAPK_DAPK_DAPK1_ST	Q13224	GRIN2B	P53355	DAPK1	S1469	R1463G	1463	Missense	distal	-6	no	9.651	7.609	EPSD	CCLE	8.849	Loss
CAMK_PKD_PRKD1_ST	Q8WUI4	HDAC7	Q15139	PRKD1	S464	V469G	469	Missense	distal	5	no	5.640	5.576	EPSD	CCLE	4.507	Down-regulation
CAMK_PKD_PRKD1_ST	Q8WUI4	HDAC7	Q15139	PRKD1	T465	V469G	469	Missense	distal	4	no	5.412	5.430	EPSD	CCLE	4.507	Up-regulation
CAMK_PKD_PRKD1_ST	Q8WUI4	HDAC7	Q15139	PRKD1	S482	S482F	482	Missense	central	0	yes	6.658	0.000	EPSD	CCLE	4.507	Loss
CAMK_PKD_PRKD1_ST	Q8WUI4	HDAC7	Q15139	PRKD1	S482	Q475H	475	Missense	distal	-7	no	6.658	6.571	EPSD	CCLE	4.507	Down-regulation
CAMK_PKD_PRKD1_ST	Q8WUI4	HDAC7	Q15139	PRKD1	S486	S482F	482	Missense	distal	-4	no	10.857	10.847	PhosphoSitePlus;EPSD	CCLE	4.507	Down-regulation
CAMK_PKD_PRKD1_ST	Q8WUI4	HDAC7	Q15139	PRKD1	S573	V580A	580	Missense	distal	7	no	8.292	8.293	EPSD	CCLE	4.507	Up-regulation
CAMK_PKD_PRKD1_ST	Q8WUI4	HDAC7	Q15139	PRKD1	S582	V580A	580	Missense	proximal	-2	no	2.818	4.974	EPSD	CCLE	4.507	Gain
CAMK_PKD_PRKD1_ST	Q8WYL5	SSH1	Q15139	PRKD1	S237	P235T	235	Missense	proximal	-2	no	6.430	6.436	EPSD	CCLE	4.507	Up-regulation
CAMK_PKD_PRKD1_ST	Q8WYL5	SSH1	Q15139	PRKD1	S402	R399P	399	Missense	distal	-3	no	8.076	4.160	EPSD;PhosphoSitePlus	CCLE	4.507	Loss
CAMK_PKD_PRKD1_ST	Q92934	BAD	Q15139	PRKD1	S74	H73Q	73	Missense	proximal	-1	no	4.622	4.611	EPSD	CCLE	4.507	Down-regulation
CAMK_PKD_PRKD1_ST	Q92934	BAD	Q15139	PRKD1	S74	R70W	70	Missense	distal	-4	no	4.622	4.609	EPSD	CCLE	4.507	Down-regulation
CAMK_PKD_PRKD1_ST	Q92934	BAD	Q15139	PRKD1	S75	H73Q	73	Missense	proximal	-2	no	8.207	8.186	PhosphoSitePlus;EPSD	CCLE	4.507	Down-regulation
CAMK_PKD_PRKD1_ST	Q92934	BAD	Q15139	PRKD1	S75	R70W	70	Missense	distal	-5	no	8.207	7.370	PhosphoSitePlus;EPSD	CCLE	4.507	Down-regulation
CAMK_PKD_PRKD1_ST	Q9UQL6	HDAC5	Q15139	PRKD1	S16	G9R	9	Missense	distal	-7	no	5.812	6.475	EPSD	CCLE	4.507	Up-regulation
CAMK_PKD_PRKD1_ST	Q9UQL6	HDAC5	Q15139	PRKD1	S24	S24P	24	Missense	central	0	yes	5.200	0.000	EPSD	CCLE	4.507	Loss
CAMK_PKD_PRKD1_ST	Q9UQL6	HDAC5	Q15139	PRKD1	S713	R710G	710	Missense	distal	-3	no	6.671	1.904	EPSD	CCLE	4.507	Loss
CAMK_PKD_PRKD1_ST	Q9UQL6	HDAC5	Q15139	PRKD1	S1108	E1113Q	1113	Missense	distal	5	no	7.248	7.281	EPSD	CCLE	4.507	Up-regulation
CAMK_PKD_PRKD1_ST	Q9UQL6	HDAC5	Q15139	PRKD1	S1108	S1108G	1108	Missense	central	0	yes	7.248	0.000	EPSD	CCLE	4.507	Loss
CAMK_PKD_PRKD1_ST	Q96QB1	DLC1	Q15139	PRKD1	S354	M355V	355	Missense	proximal	1	no	5.871	5.870	EPSD	CCLE	4.507	Down-regulation
CAMK_PKD_PRKD1_ST	Q96QB1	DLC1	Q15139	PRKD1	S354	R349S	349	Missense	distal	-5	no	5.871	5.487	EPSD	CCLE	4.507	Down-regulation
CAMK_PKD_PRKD1_ST	Q96QB1	DLC1	Q15139	PRKD1	S544	R549W	549	Missense	distal	5	no	4.714	4.595	EPSD	CCLE	4.507	Down-regulation
CAMK_PKD_PRKD1_ST	Q96QB1	DLC1	Q15139	PRKD1	S544	F540L	540	Missense	distal	-4	no	4.714	4.717	EPSD	CCLE	4.507	Up-regulation
CAMK_PKD_PRKD1_ST	Q96QB1	DLC1	Q15139	PRKD1	S548	R549W	549	Missense	proximal	1	no	6.637	6.636	EPSD	CCLE	4.507	Down-regulation
CAMK_PKD_PRKD1_ST	Q96QB1	DLC1	Q15139	PRKD1	S856	L851I	851	Missense	distal	-5	no	8.730	7.074	EPSD	CCLE	4.507	Down-regulation
CAMK_PKD_PRKD1_ST	Q96QB1	DLC1	Q15139	PRKD1	S1244	N1243K	1243	Missense	proximal	-1	no	8.627	8.724	PhosphoSitePlus	CCLE	4.507	Up-regulation
CAMK_PKD_PRKD1_ST	Q96QB1	DLC1	Q15139	PRKD1	S1355	T1348I	1348	Missense	distal	-7	no	4.622	4.434	EPSD	CCLE	4.507	Loss
CAMK_PKD_PRKD1_ST	O00429	DNM1L	Q15139	PRKD1	S529	R522T	522	Missense	distal	-7	no	5.617	5.168	EPSD	CCLE	4.507	Down-regulation
CAMK_PKD_PRKD1_ST	O00429	DNM1L	Q15139	PRKD1	S544	S548P	548	Missense	distal	4	no	4.546	4.554	EPSD	CCLE	4.507	Up-regulation
CAMK_PKD_PRKD1_ST	Q15276	RABEP1	Q15139	PRKD1	S416	G415S	415	Missense	proximal	-1	no	5.325	5.585	EPSD	CCLE	4.507	Up-regulation
CAMK_PKD_PRKD1_ST	O75628	REM1	Q15139	PRKD1	S18	L13Q	13	Missense	distal	-5	no	10.863	8.269	PhosphoSitePlus	CCLE	4.507	Down-regulation
CAMK_PKD_PRKD1_ST	O75628	REM1	Q15139	PRKD1	T19	L13Q	13	Missense	distal	-6	no	6.291	6.328	EPSD	CCLE	4.507	Up-regulation
CAMK_PKD_PRKD1_ST	O75628	REM1	Q15139	PRKD1	S250	S250R	250	Missense	central	0	yes	10.549	0.000	EPSD	CCLE	4.507	Loss
CAMK_PKD_PRKD1_ST	Q99683	MAP3K5	Q15139	PRKD1	S83	R78Q	78	Missense	distal	-5	no	4.917	4.203	EPSD	CCLE	4.507	Loss
CAMK_PKD_PRKD1_ST	Q99683	MAP3K5	Q15139	PRKD1	S719	S716N	716	Missense	distal	-3	no	5.470	4.324	EPSD	CCLE	4.507	Loss
CAMK_PKD_PRKD1_ST	O96013	PAK4	Q15139	PRKD1	S99	S93L	93	Missense	distal	-6	no	8.722	8.689	PhosphoSitePlus	CCLE	4.507	Down-regulation
CAMK_PKD_PRKD1_ST	O96013	PAK4	Q15139	PRKD1	S104	P107L	107	Missense	distal	3	no	9.929	9.931	EPSD	CCLE	4.507	Up-regulation
CAMK_PKD_PRKD1_ST	O96013	PAK4	Q15139	PRKD1	S162	S162C	162	Missense	central	0	yes	6.401	0.000	EPSD	CCLE	4.507	Loss
CAMK_PKD_PRKD1_ST	O96013	PAK4	Q15139	PRKD1	S167	S162C	162	Missense	distal	-5	no	5.995	5.950	EPSD	CCLE	4.507	Down-regulation
CAMK_PKD_PRKD1_ST	O96013	PAK4	Q15139	PRKD1	S181	R178C	178	Missense	distal	-3	no	6.506	2.409	EPSD	CCLE	4.507	Loss
CAMK_PKD_PRKD1_ST	O96013	PAK4	Q15139	PRKD1	S181	R178H	178	Missense	distal	-3	no	6.506	2.520	EPSD	CCLE	4.507	Loss
CAMK_PKD_PRKD1_ST	O96013	PAK4	Q15139	PRKD1	S343	V340M	340	Missense	distal	-3	no	3.053	5.127	EPSD	CCLE	4.507	Gain
CAMK_PKD_PRKD1_ST	O96013	PAK4	Q15139	PRKD1	S474	V476I	476	Missense	proximal	2	no	11.240	11.245	EPSD	CCLE	4.507	Up-regulation
CAMK_PKD_PRKD1_ST	Q14896	MYBPC3	Q15139	PRKD1	S275	R273C	273	Missense	proximal	-2	no	9.937	7.329	EPSD	CCLE	4.507	Down-regulation
CAMK_PKD_PRKD1_ST	Q14896	MYBPC3	Q15139	PRKD1	S275	R272C	272	Missense	distal	-3	no	9.937	5.840	EPSD	CCLE	4.507	Down-regulation
CAMK_PKD_PRKD1_ST	O60331	PIP5K1C	Q15139	PRKD1	S662	P660R	660	Missense	proximal	-2	no	3.347	5.513	EPSD	CCLE	4.507	Gain
CAMK_PKD_PRKD1_ST	Q15139	PRKD1	Q15139	PRKD1	S249	I253T	253	Missense	distal	4	no	5.773	5.777	EPSD	CCLE	4.507	Up-regulation
CAMK_PKD_PRKD1_ST	Q15139	PRKD1	Q15139	PRKD1	S420	M424V	424	Missense	distal	4	no	6.150	6.157	EPSD	CCLE	4.507	Up-regulation
CAMK_PKD_PRKD1_ST	Q15139	PRKD1	Q15139	PRKD1	S421	M424V	424	Missense	distal	3	no	6.747	6.738	EPSD	CCLE	4.507	Down-regulation
CAMK_PKD_PRKD1_ST	Q15139	PRKD1	Q15139	PRKD1	S910	G906N	906	Missense	distal	-4	no	7.394	7.396	EPSD;PhosphoSitePlus	CCLE	4.507	Up-regulation
CAMK_PKD_PRKD1_ST	Q13936	CACNA1C	Q15139	PRKD1	S1718	E1712K	1712	Missense	distal	-6	no	7.118	7.115	EPSD	CCLE	4.507	Down-regulation
CAMK_PKD_PRKD1_ST	Q14247	CTTN	Q15139	PRKD1	S113	S106L	106	Missense	distal	-7	no	8.345	7.820	EPSD	CCLE	4.507	Down-regulation
CAMK_PKD_PRKD1_ST	Q14247	CTTN	Q15139	PRKD1	S192	G196S	196	Missense	distal	4	no	4.857	4.831	EPSD	CCLE	4.507	Down-regulation
CAMK_PKD_PRKD1_ST	Q14247	CTTN	Q15139	PRKD1	S282	G286E	286	Missense	distal	4	no	7.855	7.836	EPSD	CCLE	4.507	Down-regulation
CAMK_PKD_PRKD1_ST	P05412	JUN	Q15139	PRKD1	S58	R54G	54	Missense	distal	-4	no	6.725	6.712	EPSD	CCLE	4.507	Down-regulation
CAMK_PKD_PRKD1_ST	Q9UBF8	PI4KB	Q15139	PRKD1	S294	S287G	287	Missense	distal	-7	no	8.876	8.493	PhosphoSitePlus	CCLE	4.507	Down-regulation
CAMK_PKD_PRKD1_ST	Q9Y3E5	PTRH2	Q15139	PRKD1	S87	A84T	84	Missense	distal	-3	no	5.243	4.977	EPSD;PhosphoSitePlus	CCLE	4.507	Down-regulation
CAMK_PKD_PRKD1_ST	Q9BST9	RTKN	Q15139	PRKD1	S106	E113D	113	Missense	distal	7	no	8.272	8.271	EPSD	CCLE	4.507	Down-regulation
CAMK_PKD_PRKD1_ST	Q12809	KCNH2	Q15139	PRKD1	S239	G238D	238	Missense	proximal	-1	no	4.803	4.810	EPSD	CCLE	4.507	Up-regulation
CAMK_PKD_PRKD1_ST	Q12809	KCNH2	Q15139	PRKD1	S239	R232C	232	Missense	distal	-7	no	4.803	4.350	EPSD	CCLE	4.507	Loss
CAMK_PKD_PRKD1_ST	Q12809	KCNH2	Q15139	PRKD1	S283	E289K	289	Missense	distal	6	no	8.866	8.867	EPSD	CCLE	4.507	Up-regulation
CAMK_PKD_PRKD1_ST	Q12809	KCNH2	Q15139	PRKD1	S304	S304N	304	Missense	central	0	yes	6.686	0.000	EPSD	CCLE	4.507	Loss
CAMK_PKD_PRKD1_ST	Q12809	KCNH2	Q15139	PRKD1	S320	T319P	319	Missense	proximal	-1	no	5.175	5.193	EPSD	CCLE	4.507	Up-regulation
CAMK_PKD_PRKD1_ST	Q12809	KCNH2	Q15139	PRKD1	S354	E357V	357	Missense	distal	3	no	4.638	4.633	EPSD	CCLE	4.507	Down-regulation
CAMK_PKD_PRKD1_ST	Q12809	KCNH2	Q15139	PRKD1	S890	R887H	887	Missense	distal	-3	no	9.635	5.649	EPSD	CCLE	4.507	Down-regulation
CAMK_PKD_PRKD1_ST	P05549	TFAP2A	Q15139	PRKD1	S326	T333A	333	Missense	distal	7	no	9.393	9.394	EPSD;PhosphoSitePlus	CCLE	4.507	Up-regulation
CAMK_PKD_PRKD1_ST	Q13671	RIN1	Q15139	PRKD1	S291	E290K	290	Missense	proximal	-1	no	10.565	10.610	EPSD	CCLE	4.507	Up-regulation
CAMK_PKD_PRKD1_ST	Q13671	RIN1	Q15139	PRKD1	S291	Y295C	295	Missense	distal	4	no	10.565	10.546	EPSD	CCLE	4.507	Down-regulation
CAMK_PKD_PRKD1_ST	Q13671	RIN1	Q15139	PRKD1	S292	E290K	290	Missense	proximal	-2	no	9.735	10.515	EPSD;PhosphoSitePlus	CCLE	4.507	Up-regulation
CAMK_PKD_PRKD1_ST	Q13671	RIN1	Q15139	PRKD1	S292	Y295C	295	Missense	distal	3	no	9.735	9.756	EPSD;PhosphoSitePlus	CCLE	4.507	Up-regulation
CAMK_PKD_PRKD1_ST	P16144	ITGB4	Q15139	PRKD1	S397	F390S	390	Missense	distal	-7	no	4.644	5.025	EPSD	CCLE	4.507	Up-regulation
CAMK_PKD_PRKD1_ST	P16144	ITGB4	Q15139	PRKD1	S893	R892H	892	Missense	proximal	-1	no	7.001	6.888	EPSD	CCLE	4.507	Down-regulation
CAMK_PKD_PRKD1_ST	P02686	MBP	Q15139	PRKD1	S128	S124F	124	Missense	distal	-4	no	4.768	4.758	EPSD	CCLE	4.507	Down-regulation
CAMK_PKD_PRKD1_ST	P22059	OSBP	Q15139	PRKD1	T129	R131L	131	Missense	proximal	2	no	5.434	5.344	EPSD	CCLE	4.507	Down-regulation
CAMK_PKD_PRKD1_ST	P22059	OSBP	Q15139	PRKD1	S240	S244F	244	Missense	distal	4	no	9.709	9.733	PhosphoSitePlus	CCLE	4.507	Up-regulation
CAMK_PKD_PRKD1_ST	P22059	OSBP	Q15139	PRKD1	T377	H374Y	374	Missense	distal	-3	no	4.972	3.015	EPSD	CCLE	4.507	Loss
CAMK_PKD_PRKD1_ST	P22059	OSBP	Q15139	PRKD1	T377	G373D	373	Missense	distal	-4	no	4.972	4.971	EPSD	CCLE	4.507	Down-regulation
CAMK_PKD_PRKD1_ST	P22059	OSBP	Q15139	PRKD1	S379	H374Y	374	Missense	distal	-5	no	6.164	5.059	EPSD	CCLE	4.507	Down-regulation
CAMK_PKD_PRKD1_ST	P22059	OSBP	Q15139	PRKD1	S379	G373D	373	Missense	distal	-6	no	6.164	6.171	EPSD	CCLE	4.507	Up-regulation
CAMK_PKD_PRKD1_ST	P50552	VASP	Q15139	PRKD1	S322	S324C	324	Missense	proximal	2	no	9.307	9.250	EPSD;PhosphoSitePlus	CCLE	4.507	Down-regulation
CAMK_PKD_PRKD1_ST	P50552	VASP	Q15139	PRKD1	S324	S324C	324	Missense	central	0	yes	5.019	0.000	EPSD	CCLE	4.507	Loss
CAMK_PKD_PRKD1_ST	O14558	HSPB6	Q15139	PRKD1	S59	P58S	58	Missense	proximal	-1	no	7.550	7.646	EPSD	CCLE	4.507	Up-regulation
CAMK_PKD_PRKD1_ST	O14558	HSPB6	Q15139	PRKD1	S59	R56H	56	Missense	distal	-3	no	7.550	3.563	EPSD	CCLE	4.507	Loss
CAMK_PKD_PRKD1_ST	Q92918	MAP4K1	Q15139	PRKD1	S430	V424A	424	Missense	distal	-6	no	8.323	8.348	EPSD	CCLE	4.507	Up-regulation
CAMK_PKD_PRKD1_ST	Q92918	MAP4K1	Q15139	PRKD1	S430	G423E	423	Missense	distal	-7	no	8.323	8.652	EPSD	CCLE	4.507	Up-regulation
CAMK_PKD_PRKD1_ST	P04792	HSPB1	Q15139	PRKD1	S82	S78T	78	Missense	distal	-4	no	10.184	10.180	PhosphoSitePlus	CCLE	4.507	Down-regulation
TK_PDGFR_KIT_Y	P10721	KIT	P10721	KIT	Y568	I563T	563	Missense	distal	-5	no	3.400	2.842	EPSD;PhosphoSitePlus	CCLE	1.639	Down-regulation
TK_PDGFR_KIT_Y	P10721	KIT	P10721	KIT	Y570	I563T	563	Missense	distal	-7	no	3.527	3.347	EPSD;PhosphoSitePlus	CCLE	1.639	Down-regulation
TK_PDGFR_KIT_Y	P10721	KIT	P10721	KIT	Y578	F584C	584	Missense	distal	6	no	1.744	1.779	EPSD	CCLE	1.639	Up-regulation
TK_PDGFR_KIT_Y	P10721	KIT	P10721	KIT	Y721	S715N	715	Missense	distal	-6	no	3.319	3.370	EPSD;PhosphoSitePlus	CCLE	1.639	Up-regulation
Other_PEK_PKR_EIF2AK2_ST	P05198	EIF2S1	P19525	EIF2AK2	S49	G44D	44	Missense	distal	-5	no	99.991	98.581	PhosphoSitePlus;EPSD	CCLE	66.906	Down-regulation
Other_PEK_PKR_EIF2AK2_ST	P10636	MAPT	P19525	EIF2AK2	T111	G107V	107	Missense	distal	-4	no	71.982	76.321	EPSD	CCLE	66.906	Up-regulation
Other_PEK_PKR_EIF2AK2_ST	P10636	MAPT	P19525	EIF2AK2	S575	K574N	574	Missense	proximal	-1	no	73.751	74.550	EPSD	CCLE	66.906	Up-regulation
Other_PEK_PKR_EIF2AK2_ST	P10636	MAPT	P19525	EIF2AK2	S579	K574N	574	Missense	distal	-5	no	104.255	101.879	EPSD	CCLE	66.906	Down-regulation
Other_PEK_PKR_EIF2AK2_ST	P10636	MAPT	P19525	EIF2AK2	T580	K574N	574	Missense	distal	-6	no	92.966	69.267	EPSD	CCLE	66.906	Down-regulation
Other_PEK_PKR_EIF2AK2_ST	P10636	MAPT	P19525	EIF2AK2	S637	D631E	631	Missense	distal	-6	no	71.789	89.094	EPSD	CCLE	66.906	Up-regulation
Other_PEK_PKR_EIF2AK2_ST	P04637	TP53	P19525	EIF2AK2	S149	P142R	142	Missense	distal	-7	no	69.762	69.458	EPSD	CCLE	66.906	Down-regulation
TK_Eph_EPHA2_Y	P29317	EPHA2	P29317	EPHA2	Y694	E693K	693	Missense	proximal	-1	no	2.212	2.014	EPSD;PhosphoSitePlus	CCLE	1.229	Down-regulation
TK_Eph_EPHA2_Y	P29317	EPHA2	P29317	EPHA2	Y772	A770T	770	Missense	proximal	-2	no	2.847	2.781	PhosphoSitePlus;EPSD	CCLE	1.229	Down-regulation
CAMK_CAMKL_LKB_STK11_ST	Q13485	SMAD4	Q15831	STK11	S171	D165E	165	Missense	distal	-6	no	23.775	23.805	EPSD	CCLE	16.403	Up-regulation
CAMK_CAMKL_LKB_STK11_ST	P27448	MARK3	Q15831	STK11	T204	F203V	203	Missense	proximal	-1	no	26.250	26.082	EPSD	CCLE	16.403	Down-regulation
CAMK_CAMKL_LKB_STK11_ST	Q6UUV9	CRTC1	Q15831	STK11	S572	T578S	578	Missense	distal	6	no	18.026	17.526	EPSD	CCLE	16.403	Down-regulation
CAMK_CAMKL_LKB_STK11_ST	Q15831	STK11	Q15831	STK11	T185	L183V	183	Missense	proximal	-2	no	34.196	27.969	EPSD;PhosphoSitePlus	CCLE	16.403	Down-regulation
CAMK_CAMKL_LKB_STK11_ST	Q15831	STK11	Q15831	STK11	T189	L183V	183	Missense	distal	-6	no	36.410	36.385	EPSD;PhosphoSitePlus	CCLE	16.403	Down-regulation
CAMK_CAMKL_LKB_STK11_ST	Q15831	STK11	Q15831	STK11	T189	L195Q	195	Missense	distal	6	no	36.410	36.606	EPSD;PhosphoSitePlus	CCLE	16.403	Up-regulation
CAMK_CAMKL_LKB_STK11_ST	Q15831	STK11	Q15831	STK11	T402	E396K	396	Missense	distal	-6	no	28.705	28.717	EPSD;PhosphoSitePlus	CCLE	16.403	Up-regulation
CAMK_CAMKL_LKB_STK11_ST	Q15831	STK11	Q15831	STK11	T402	A398T	398	Missense	distal	-4	no	28.705	28.697	EPSD;PhosphoSitePlus	CCLE	16.403	Down-regulation
CAMK_CAMKL_LKB_STK11_ST	Q15831	STK11	Q15831	STK11	T402	A398G	398	Missense	distal	-4	no	28.705	28.556	EPSD;PhosphoSitePlus	CCLE	16.403	Down-regulation
CAMK_CAMKL_LKB_STK11_ST	Q15831	STK11	Q15831	STK11	T402	E407D	407	Missense	distal	5	no	28.705	29.063	EPSD;PhosphoSitePlus	CCLE	16.403	Up-regulation
CAMK_CAMKL_LKB_STK11_ST	P57059	SIK1	Q15831	STK11	T182	S176P	176	Missense	distal	-6	no	55.113	55.073	PhosphoSitePlus	CCLE	16.403	Down-regulation
CAMK_CAMKL_LKB_STK11_ST	O14744	PRMT5	Q15831	STK11	T173	E169Q	169	Missense	distal	-4	no	16.679	16.257	EPSD	CCLE	16.403	Loss
CAMK_CAMKL_LKB_STK11_ST	O60285	NUAK1	Q15831	STK11	S542	P546L	546	Missense	distal	4	no	24.505	24.710	EPSD	CCLE	16.403	Up-regulation
CAMK_CAMKL_LKB_STK11_ST	O60285	NUAK1	Q15831	STK11	T547	E553Q	553	Missense	distal	6	no	18.532	15.981	EPSD	CCLE	16.403	Loss
CAMK_CAMKL_LKB_STK11_ST	O60285	NUAK1	Q15831	STK11	T547	P546L	546	Missense	proximal	-1	no	18.532	19.431	EPSD	CCLE	16.403	Up-regulation
CAMK_CAMKL_LKB_STK11_ST	O60285	NUAK1	Q15831	STK11	S550	E553Q	553	Missense	distal	3	no	17.108	12.434	EPSD	CCLE	16.403	Loss
CAMK_CAMKL_LKB_STK11_ST	O60285	NUAK1	Q15831	STK11	S550	P546L	546	Missense	distal	-4	no	17.108	16.469	EPSD	CCLE	16.403	Down-regulation
CAMK_CAMKL_LKB_STK11_ST	Q13153	PAK1	Q15831	STK11	S199	E195Q	195	Missense	distal	-4	no	18.471	18.049	EPSD	CCLE	16.403	Down-regulation
CAMK_CAMKL_LKB_STK11_ST	Q13153	PAK1	Q15831	STK11	S199	P194L	194	Missense	distal	-5	no	18.471	15.929	EPSD	CCLE	16.403	Loss
CAMK_CAMKL_LKB_STK11_ST	Q14680	MELK	Q15831	STK11	T167	A173T	173	Missense	distal	6	no	44.373	44.677	PhosphoSitePlus	CCLE	16.403	Up-regulation
CAMK_CAMKL_LKB_STK11_ST	Q14680	MELK	Q15831	STK11	T566	V563M	563	Missense	distal	-3	no	18.093	18.263	EPSD	CCLE	16.403	Up-regulation
CAMK_CAMKL_LKB_STK11_ST	Q13131	PRKAA1	Q15831	STK11	T355	S356N	356	Missense	proximal	1	no	21.212	21.217	EPSD	CCLE	16.403	Up-regulation
CAMK_CAMKL_LKB_STK11_ST	Q13131	PRKAA1	Q15831	STK11	S496	S494L	494	Missense	proximal	-2	no	38.291	42.121	EPSD	CCLE	16.403	Up-regulation
CAMK_CAMKL_LKB_STK11_ST	Q13131	PRKAA1	Q15831	STK11	S496	S494W	494	Missense	proximal	-2	no	38.291	35.419	EPSD	CCLE	16.403	Down-regulation
CAMK_CAMKL_LKB_STK11_ST	Q13131	PRKAA1	Q15831	STK11	T526	L521V	521	Missense	distal	-5	no	23.758	25.174	EPSD	CCLE	16.403	Up-regulation
CAMK_CAMKL_LKB_STK11_ST	Q96L34	MARK4	Q15831	STK11	S458	R455G	455	Missense	distal	-3	no	18.884	18.874	EPSD	CCLE	16.403	Down-regulation
CAMK_CAMKL_LKB_STK11_ST	Q96L34	MARK4	Q15831	STK11	T568	Q573H	573	Missense	distal	5	no	24.452	24.705	EPSD	CCLE	16.403	Up-regulation
CAMK_CAMKL_LKB_STK11_ST	Q8IWQ3	BRSK2	Q15831	STK11	T389	G391D	391	Missense	proximal	2	no	20.572	27.411	EPSD	CCLE	16.403	Up-regulation
CAMK_CAMKL_LKB_STK11_ST	Q9P0L2	MARK1	Q15831	STK11	T613	S610R	610	Missense	distal	-3	no	21.439	21.310	EPSD	CCLE	16.403	Down-regulation
CAMK_CAMKL_LKB_STK11_ST	P46937	YAP1	Q15831	STK11	T425	D421N	421	Missense	distal	-4	no	27.793	27.796	EPSD	CCLE	16.403	Up-regulation
CAMK_CAMKL_LKB_STK11_ST	Q9H0K1	SIK2	Q15831	STK11	T175	W176R	176	Missense	proximal	1	no	60.719	60.702	PhosphoSitePlus	CCLE	16.403	Down-regulation
CAMK_CAMKL_LKB_STK11_ST	Q9NRH2	SNRK	Q15831	STK11	T157	T157I	157	Missense	central	0	yes	27.664	0.000	EPSD	CCLE	16.403	Loss
CAMK_CAMKL_MARK_MARK1_ST	P10636	MAPT	Q9P0L2	MARK1	T71	A66V	66	Missense	distal	-5	no	0.253	0.251	EPSD	CCLE	0.230	Down-regulation
CAMK_CAMKL_MARK_MARK1_ST	P10636	MAPT	Q9P0L2	MARK1	S228	D221Y	221	Missense	distal	-7	no	0.334	0.310	EPSD	CCLE	0.230	Down-regulation
CAMK_CAMKL_MARK_MARK1_ST	P10636	MAPT	Q9P0L2	MARK1	S228	P234S	234	Missense	distal	6	no	0.334	0.328	EPSD	CCLE	0.230	Down-regulation
CAMK_CAMKL_MARK_MARK1_ST	P10636	MAPT	Q9P0L2	MARK1	S447	V442I	442	Missense	distal	-5	no	0.378	0.380	EPSD	CCLE	0.230	Up-regulation
CAMK_CAMKL_MARK_MARK1_ST	P10636	MAPT	Q9P0L2	MARK1	S512	R511H	511	Missense	proximal	-1	no	0.259	0.253	EPSD	CCLE	0.230	Down-regulation
CAMK_CAMKL_MARK_MARK1_ST	P10636	MAPT	Q9P0L2	MARK1	S512	G518S	518	Missense	distal	6	no	0.259	0.261	EPSD	CCLE	0.230	Up-regulation
CAMK_CAMKL_MARK_MARK1_ST	P10636	MAPT	Q9P0L2	MARK1	S527	R526L	526	Missense	proximal	-1	no	0.291	0.274	EPSD	CCLE	0.230	Down-regulation
CAMK_CAMKL_MARK_MARK1_ST	P10636	MAPT	Q9P0L2	MARK1	T529	R526L	526	Missense	distal	-3	no	0.238	0.234	EPSD	CCLE	0.230	Down-regulation
CAMK_CAMKL_MARK_MARK1_ST	P10636	MAPT	Q9P0L2	MARK1	S531	R526L	526	Missense	distal	-5	no	0.313	0.317	EPSD	CCLE	0.230	Up-regulation
CAMK_CAMKL_MARK_MARK1_ST	P10636	MAPT	Q9P0L2	MARK1	S558	R559H	559	Missense	proximal	1	no	0.264	0.270	EPSD	CCLE	0.230	Up-regulation
CAMK_CAMKL_MARK_MARK1_ST	P10636	MAPT	Q9P0L2	MARK1	S575	K574N	574	Missense	proximal	-1	no	0.346	0.329	EPSD	CCLE	0.230	Down-regulation
CAMK_CAMKL_MARK_MARK1_ST	P10636	MAPT	Q9P0L2	MARK1	S579	K574N	574	Missense	distal	-5	no	0.613	0.611	EPSD	CCLE	0.230	Down-regulation
CAMK_CAMKL_MARK_MARK1_ST	P10636	MAPT	Q9P0L2	MARK1	S637	D631E	631	Missense	distal	-6	no	0.477	0.498	EPSD	CCLE	0.230	Up-regulation
CAMK_CAMKL_MARK_MARK1_ST	P10636	MAPT	Q9P0L2	MARK1	S713	G706V	706	Missense	distal	-7	no	0.470	0.448	EPSD	CCLE	0.230	Down-regulation
CAMK_CAMKL_MARK_MARK1_ST	P10636	MAPT	Q9P0L2	MARK1	S713	S717C	717	Missense	distal	4	no	0.470	0.444	EPSD	CCLE	0.230	Down-regulation
CAMK_CAMKL_MARK_MARK1_ST	P10636	MAPT	Q9P0L2	MARK1	S726	S721C	721	Missense	distal	-5	no	0.238	0.240	EPSD	CCLE	0.230	Up-regulation
CAMK_CAMKL_MARK_MARK1_ST	P10636	MAPT	Q9P0L2	MARK1	S726	H724R	724	Missense	proximal	-2	no	0.238	0.235	EPSD	CCLE	0.230	Down-regulation
CAMK_CAMKL_MARK_MARK1_ST	P10636	MAPT	Q9P0L2	MARK1	S739	Q741K	741	Missense	proximal	2	no	0.354	0.349	EPSD	CCLE	0.230	Down-regulation
AGC_GRK_GRK_GRK7_ST	Q16625	OCLN	Q8WTQ7	GRK7	S370	Q365K	365	Missense	distal	-5	no	1.089	1.207	EPSD	CCLE	1.098	Gain
CAMK_CAMKL_MARK_MARK2_ST	Q8WUI4	HDAC7	Q7KZI7	MARK2	T104	S109N	109	Missense	distal	5	no	266.611	271.431	EPSD	CCLE	271.430	Gain
CAMK_CAMKL_MARK_MARK2_ST	Q8WUI4	HDAC7	Q7KZI7	MARK2	T465	V469G	469	Missense	distal	4	no	257.253	282.468	EPSD	CCLE	271.430	Gain
CAMK_CAMKL_MARK_MARK2_ST	Q8WUI4	HDAC7	Q7KZI7	MARK2	S573	V580A	580	Missense	distal	7	no	330.402	312.507	EPSD	CCLE	271.430	Down-regulation
CAMK_CAMKL_MARK_MARK2_ST	P56524	HDAC4	Q7KZI7	MARK2	S246	L252S	252	Missense	distal	6	no	407.942	394.851	PhosphoSitePlus	CCLE	271.430	Down-regulation
CAMK_CAMKL_MARK_MARK2_ST	P56524	HDAC4	Q7KZI7	MARK2	S293	A291T	291	Missense	proximal	-2	no	292.315	292.866	EPSD	CCLE	271.430	Up-regulation
CAMK_CAMKL_MARK_MARK2_ST	Q8TEW0	PARD3	Q7KZI7	MARK2	T468	G470S	470	Missense	proximal	2	no	273.513	300.084	EPSD	CCLE	271.430	Up-regulation
CAMK_CAMKL_MARK_MARK2_ST	Q8TEW0	PARD3	Q7KZI7	MARK2	S604	R609Q	609	Missense	distal	5	no	274.692	265.292	EPSD	CCLE	271.430	Loss
CAMK_CAMKL_MARK_MARK2_ST	Q8TEW0	PARD3	Q7KZI7	MARK2	S873	K870R	870	Missense	distal	-3	no	341.821	349.470	PhosphoSitePlus;EPSD	CCLE	271.430	Up-regulation
CAMK_CAMKL_MARK_MARK2_ST	Q8TEW0	PARD3	Q7KZI7	MARK2	S875	K870R	870	Missense	distal	-5	no	281.356	275.438	EPSD	CCLE	271.430	Down-regulation
CAMK_CAMKL_MARK_MARK2_ST	Q8TEW0	PARD3	Q7KZI7	MARK2	S1196	E1200V	1200	Missense	distal	4	no	275.712	287.134	EPSD	CCLE	271.430	Up-regulation
CAMK_CAMKL_MARK_MARK2_ST	Q92974	ARHGEF2	Q7KZI7	MARK2	S142	A147T	147	Missense	distal	5	no	302.986	315.096	EPSD	CCLE	271.430	Up-regulation
CAMK_CAMKL_MARK_MARK2_ST	Q92974	ARHGEF2	Q7KZI7	MARK2	S143	A147T	147	Missense	distal	4	no	344.445	320.284	EPSD;PhosphoSitePlus	CCLE	271.430	Down-regulation
CAMK_CAMKL_MARK_MARK2_ST	Q92974	ARHGEF2	Q7KZI7	MARK2	S151	A147T	147	Missense	distal	-4	no	326.944	339.829	EPSD	CCLE	271.430	Up-regulation
CAMK_CAMKL_MARK_MARK2_ST	Q92974	ARHGEF2	Q7KZI7	MARK2	S163	R168H	168	Missense	distal	5	no	307.534	303.926	EPSD	CCLE	271.430	Down-regulation
CAMK_CAMKL_MARK_MARK2_ST	Q92974	ARHGEF2	Q7KZI7	MARK2	S172	R168H	168	Missense	distal	-4	no	393.740	379.825	EPSD;PhosphoSitePlus	CCLE	271.430	Down-regulation
CAMK_CAMKL_MARK_MARK2_ST	Q92974	ARHGEF2	Q7KZI7	MARK2	S174	R168H	168	Missense	distal	-6	no	296.599	295.860	EPSD	CCLE	271.430	Down-regulation
CAMK_CAMKL_MARK_MARK2_ST	Q92974	ARHGEF2	Q7KZI7	MARK2	T175	R168H	168	Missense	distal	-7	no	275.823	275.880	EPSD	CCLE	271.430	Up-regulation
CAMK_CAMKL_MARK_MARK2_ST	Q92974	ARHGEF2	Q7KZI7	MARK2	S186	E193Q	193	Missense	distal	7	no	361.943	354.022	EPSD;PhosphoSitePlus	CCLE	271.430	Down-regulation
CAMK_CAMKL_MARK_MARK2_ST	Q92974	ARHGEF2	Q7KZI7	MARK2	T455	A453T	453	Missense	proximal	-2	no	337.862	338.413	EPSD	CCLE	271.430	Up-regulation
CAMK_CAMKL_MARK_MARK2_ST	Q92974	ARHGEF2	Q7KZI7	MARK2	S519	V521A	521	Missense	proximal	2	no	272.266	251.111	EPSD	CCLE	271.430	Loss
CAMK_CAMKL_MARK_MARK2_ST	Q92974	ARHGEF2	Q7KZI7	MARK2	S782	R779Q	779	Missense	distal	-3	no	276.770	174.727	EPSD	CCLE	271.430	Loss
CAMK_CAMKL_MARK_MARK2_ST	Q92974	ARHGEF2	Q7KZI7	MARK2	T802	R809Q	809	Missense	distal	7	no	282.521	265.271	EPSD	CCLE	271.430	Loss
CAMK_CAMKL_MARK_MARK2_ST	Q92974	ARHGEF2	Q7KZI7	MARK2	T802	Q808H	808	Missense	distal	6	no	282.521	294.647	EPSD	CCLE	271.430	Up-regulation
CAMK_CAMKL_MARK_MARK2_ST	Q92974	ARHGEF2	Q7KZI7	MARK2	T802	T802A	802	Missense	central	0	yes	282.521	0.000	EPSD	CCLE	271.430	Loss
CAMK_CAMKL_MARK_MARK2_ST	P10636	MAPT	Q7KZI7	MARK2	S214	D221Y	221	Missense	distal	7	no	313.338	309.116	EPSD	CCLE	271.430	Down-regulation
CAMK_CAMKL_MARK_MARK2_ST	P10636	MAPT	Q7KZI7	MARK2	S552	R559H	559	Missense	distal	7	no	297.605	288.609	EPSD	CCLE	271.430	Down-regulation
CAMK_CAMKL_MARK_MARK2_ST	P10636	MAPT	Q7KZI7	MARK2	S579	K574N	574	Missense	distal	-5	no	410.485	416.926	EPSD	CCLE	271.430	Up-regulation
CAMK_CAMKL_MARK_MARK2_ST	P10636	MAPT	Q7KZI7	MARK2	T703	G706V	706	Missense	distal	3	no	264.348	304.813	EPSD	CCLE	271.430	Gain
CAMK_CAMKL_MARK_MARK2_ST	P10636	MAPT	Q7KZI7	MARK2	S730	H724R	724	Missense	distal	-6	no	282.244	282.983	EPSD	CCLE	271.430	Up-regulation
CAMK_CAMKL_MARK_MARK2_ST	P10636	MAPT	Q7KZI7	MARK2	T744	Q741K	741	Missense	distal	-3	no	205.321	299.715	EPSD	CCLE	271.430	Gain
CAMK_CAMKL_MARK_MARK2_ST	Q9NQT8	KIF13B	Q7KZI7	MARK2	T233	T233I	233	Missense	central	0	yes	309.274	0.000	EPSD	CCLE	271.430	Loss
CAMK_CAMKL_MARK_MARK2_ST	Q9NQT8	KIF13B	Q7KZI7	MARK2	S1481	R1476K	1476	Missense	distal	-5	no	298.714	304.631	EPSD	CCLE	271.430	Up-regulation
CAMK_CAMKL_MARK_MARK2_ST	Q7L804	RAB11FIP2	Q7KZI7	MARK2	S150	M151I	151	Missense	proximal	1	no	287.118	291.944	EPSD	CCLE	271.430	Up-regulation
CAMK_CAMKL_MARK_MARK2_ST	Q7L804	RAB11FIP2	Q7KZI7	MARK2	S150	N146S	146	Missense	distal	-4	no	287.118	283.841	EPSD	CCLE	271.430	Down-regulation
CAMK_CAMKL_MARK_MARK2_ST	Q7L804	RAB11FIP2	Q7KZI7	MARK2	S227	G233E	233	Missense	distal	6	no	390.699	382.919	PhosphoSitePlus	CCLE	271.430	Down-regulation
CAMK_CAMKL_MARK_MARK2_ST	Q7L804	RAB11FIP2	Q7KZI7	MARK2	S238	G233E	233	Missense	distal	-5	no	280.824	278.721	EPSD	CCLE	271.430	Down-regulation
CAMK_CAMKL_MARK_MARK2_ST	Q7L804	RAB11FIP2	Q7KZI7	MARK2	S429	E431D	431	Missense	proximal	2	no	289.765	302.332	EPSD	CCLE	271.430	Up-regulation
CAMK_CAMKL_MARK_MARK2_ST	Q7L804	RAB11FIP2	Q7KZI7	MARK2	S429	S426N	426	Missense	distal	-3	no	289.765	318.721	EPSD	CCLE	271.430	Up-regulation
CAMK_CAMKL_MARK_MARK2_ST	Q7L804	RAB11FIP2	Q7KZI7	MARK2	S429	M425V	425	Missense	distal	-4	no	289.765	296.892	EPSD	CCLE	271.430	Up-regulation
CAMK_CAMKL_MARK_MARK2_ST	P78352	DLG4	Q7KZI7	MARK2	T442	D438Y	438	Missense	distal	-4	no	314.949	305.192	EPSD	CCLE	271.430	Down-regulation
CAMK_CAMKL_MARK_MARK2_ST	P78352	DLG4	Q7KZI7	MARK2	S478	R475Q	475	Missense	distal	-3	no	325.676	223.633	EPSD	CCLE	271.430	Loss
CAMK_CAMKL_MARK_MARK2_ST	P78352	DLG4	Q7KZI7	MARK2	S480	R475Q	475	Missense	distal	-5	no	339.005	328.113	EPSD	CCLE	271.430	Down-regulation
CAMK_CAMKL_MARK_MARK2_ST	P78352	DLG4	Q7KZI7	MARK2	S654	A647T	647	Missense	distal	-7	no	340.206	340.157	EPSD	CCLE	271.430	Down-regulation
CAMK_CAMKL_MARK_MARK2_ST	Q9UQB8	BAIAP2	Q7KZI7	MARK2	S6	L12R	12	Missense	distal	6	no	318.611	310.572	EPSD	CCLE	271.430	Down-regulation
CAMK_CAMKL_MARK_MARK2_ST	Q9UQB8	BAIAP2	Q7KZI7	MARK2	T355	S352R	352	Missense	distal	-3	no	286.952	355.473	EPSD	CCLE	271.430	Up-regulation
CAMK_CAMKL_MARK_MARK2_ST	Q9UQB8	BAIAP2	Q7KZI7	MARK2	T355	L361M	361	Missense	distal	6	no	286.952	270.953	EPSD	CCLE	271.430	Loss
CAMK_CAMKL_MARK_MARK2_ST	Q9UQB8	BAIAP2	Q7KZI7	MARK2	T356	S352R	352	Missense	distal	-4	no	278.310	277.912	EPSD	CCLE	271.430	Down-regulation
CAMK_CAMKL_MARK_MARK2_ST	Q9UQB8	BAIAP2	Q7KZI7	MARK2	T356	L361M	361	Missense	distal	5	no	278.310	266.710	EPSD	CCLE	271.430	Loss
CAMK_CAMKL_MARK_MARK2_ST	Q9UQB8	BAIAP2	Q7KZI7	MARK2	S364	L361M	361	Missense	distal	-3	no	305.903	239.850	EPSD	CCLE	271.430	Loss
CAMK_CAMKL_MARK_MARK2_ST	Q9UQB8	BAIAP2	Q7KZI7	MARK2	S366	L361M	361	Missense	distal	-5	no	364.709	359.918	PhosphoSitePlus	CCLE	271.430	Down-regulation
CAMK_CAMKL_MARK_MARK2_ST	Q9BXM7	PINK1	Q7KZI7	MARK2	S495	S499F	499	Missense	distal	4	no	250.144	304.169	EPSD	CCLE	271.430	Gain
CAMK_CAMKL_MARK_MARK2_ST	P46939	UTRN	Q7KZI7	MARK2	S1795	E1800G	1800	Missense	distal	5	no	293.587	291.714	EPSD	CCLE	271.430	Down-regulation
CAMK_CAMKL_MARK_MARK2_ST	P46939	UTRN	Q7KZI7	MARK2	S1796	E1800G	1800	Missense	distal	4	no	269.882	306.519	EPSD	CCLE	271.430	Gain
CAMK_CAMKL_MARK_MARK2_ST	P46939	UTRN	Q7KZI7	MARK2	S2567	N2562Y	2562	Missense	distal	-5	no	286.958	270.791	EPSD	CCLE	271.430	Loss
CAMK_CAMKL_MARK_MARK2_ST	Q9UQL6	HDAC5	Q7KZI7	MARK2	S16	G9R	9	Missense	distal	-7	no	371.604	371.488	EPSD	CCLE	271.430	Down-regulation
CAMK_CAMKL_MARK_MARK2_ST	Q6WKZ4	RAB11FIP1	Q7KZI7	MARK2	T219	L221R	221	Missense	proximal	2	no	280.278	293.275	EPSD	CCLE	271.430	Up-regulation
CAMK_CAMKL_MARK_MARK2_ST	Q6WKZ4	RAB11FIP1	Q7KZI7	MARK2	S222	L221R	221	Missense	proximal	-1	no	289.228	279.168	EPSD	CCLE	271.430	Down-regulation
CAMK_CAMKL_MARK_MARK2_ST	Q6WKZ4	RAB11FIP1	Q7KZI7	MARK2	S224	L221R	221	Missense	distal	-3	no	344.013	377.920	EPSD	CCLE	271.430	Up-regulation
CAMK_CAMKL_MARK_MARK2_ST	Q6WKZ4	RAB11FIP1	Q7KZI7	MARK2	S268	D264V	264	Missense	distal	-4	no	282.540	267.772	EPSD	CCLE	271.430	Loss
CAMK_CAMKL_MARK_MARK2_ST	Q6WKZ4	RAB11FIP1	Q7KZI7	MARK2	S382	D388E	388	Missense	distal	6	no	291.698	289.943	EPSD	CCLE	271.430	Down-regulation
AGC_SGK_SGK1_ST	O00213	APBB1	O00141	SGK1	S695	S695L	695	Missense	central	0	yes	9.621	0.000	EPSD	CCLE	9.140	Loss
AGC_SGK_SGK1_ST	Q92597	NDRG1	O00141	SGK1	S354	S354F	354	Missense	central	0	yes	16.892	0.000	EPSD	CCLE	9.140	Loss
AGC_SGK_SGK1_ST	Q92597	NDRG1	O00141	SGK1	T356	S354F	354	Missense	proximal	-2	no	17.543	16.701	EPSD;PhosphoSitePlus	CCLE	9.140	Down-regulation
AGC_SGK_SGK1_ST	Q92597	NDRG1	O00141	SGK1	S364	H371Q	371	Missense	distal	7	no	15.470	15.587	EPSD	CCLE	9.140	Up-regulation
AGC_SGK_SGK1_ST	Q92597	NDRG1	O00141	SGK1	T366	H371Q	371	Missense	distal	5	no	19.819	19.809	EPSD;PhosphoSitePlus	CCLE	9.140	Down-regulation
AGC_SGK_SGK1_ST	P49815	TSC2	O00141	SGK1	S540	R537P	537	Missense	distal	-3	no	9.702	-2.395	EPSD	CCLE	9.140	Loss
AGC_SGK_SGK1_ST	P49815	TSC2	O00141	SGK1	S540	S538F	538	Missense	proximal	-2	no	9.702	8.860	EPSD	CCLE	9.140	Loss
AGC_SGK_SGK1_ST	P49815	TSC2	O00141	SGK1	T993	L995I	995	Missense	proximal	2	no	17.102	17.241	EPSD	CCLE	9.140	Up-regulation
AGC_SGK_SGK1_ST	P49815	TSC2	O00141	SGK1	S1130	L1137P	1137	Missense	distal	7	no	18.186	18.238	EPSD;PhosphoSitePlus	CCLE	9.140	Up-regulation
AGC_SGK_SGK1_ST	P49815	TSC2	O00141	SGK1	S1132	L1137P	1137	Missense	distal	5	no	18.303	18.281	EPSD;PhosphoSitePlus	CCLE	9.140	Down-regulation
AGC_SGK_SGK1_ST	P49815	TSC2	O00141	SGK1	S1364	I1357L	1357	Missense	distal	-7	no	10.900	10.653	EPSD	CCLE	9.140	Down-regulation
AGC_SGK_SGK1_ST	P49815	TSC2	O00141	SGK1	S1364	V1363I	1363	Missense	proximal	-1	no	10.900	10.943	EPSD	CCLE	9.140	Up-regulation
AGC_SGK_SGK1_ST	P49815	TSC2	O00141	SGK1	S1364	E1366K	1366	Missense	proximal	2	no	10.900	10.666	EPSD	CCLE	9.140	Down-regulation
AGC_SGK_SGK1_ST	P49815	TSC2	O00141	SGK1	S1420	A1416V	1416	Missense	distal	-4	no	10.901	9.365	EPSD	CCLE	9.140	Down-regulation
AGC_SGK_SGK1_ST	P49815	TSC2	O00141	SGK1	T1422	A1416V	1416	Missense	distal	-6	no	9.315	8.922	EPSD	CCLE	9.140	Loss
AGC_SGK_SGK1_ST	P49815	TSC2	O00141	SGK1	S1454	P1458T	1458	Missense	distal	4	no	10.461	10.621	EPSD	CCLE	9.140	Up-regulation
AGC_SGK_SGK1_ST	P49815	TSC2	O00141	SGK1	T1462	P1458T	1458	Missense	distal	-4	no	18.725	19.208	PhosphoSitePlus;EPSD	CCLE	9.140	Up-regulation
AGC_SGK_SGK1_ST	P49815	TSC2	O00141	SGK1	S1464	P1458T	1458	Missense	distal	-6	no	12.564	12.747	EPSD	CCLE	9.140	Up-regulation
AGC_SGK_SGK1_ST	O60343	TBC1D4	O00141	SGK1	S304	R299W	299	Missense	distal	-5	no	13.809	6.151	EPSD	CCLE	9.140	Loss
AGC_SGK_SGK1_ST	O60343	TBC1D4	O00141	SGK1	S318	V322M	322	Missense	distal	4	no	18.274	18.398	PhosphoSitePlus;EPSD	CCLE	9.140	Up-regulation
AGC_SGK_SGK1_ST	O60343	TBC1D4	O00141	SGK1	S341	P343S	343	Missense	proximal	2	no	18.973	18.792	EPSD;PhosphoSitePlus	CCLE	9.140	Down-regulation
AGC_SGK_SGK1_ST	O60343	TBC1D4	O00141	SGK1	S445	L452Q	452	Missense	distal	7	no	9.160	9.071	EPSD	CCLE	9.140	Loss
AGC_SGK_SGK1_ST	O60343	TBC1D4	O00141	SGK1	S445	Q449H	449	Missense	distal	4	no	9.160	9.236	EPSD	CCLE	9.140	Up-regulation
AGC_SGK_SGK1_ST	O60343	TBC1D4	O00141	SGK1	S445	Q449L	449	Missense	distal	4	no	9.160	9.130	EPSD	CCLE	9.140	Loss
AGC_SGK_SGK1_ST	O60343	TBC1D4	O00141	SGK1	S600	S597R	597	Missense	distal	-3	no	2.504	9.410	EPSD	CCLE	9.140	Gain
AGC_SGK_SGK1_ST	O60343	TBC1D4	O00141	SGK1	T642	R639W	639	Missense	distal	-3	no	17.501	7.806	EPSD;PhosphoSitePlus	CCLE	9.140	Loss
AGC_SGK_SGK1_ST	O60343	TBC1D4	O00141	SGK1	S644	R639W	639	Missense	distal	-5	no	9.429	1.772	EPSD	CCLE	9.140	Loss
AGC_SGK_SGK1_ST	O60343	TBC1D4	O00141	SGK1	S666	R660M	660	Missense	distal	-6	no	10.493	10.331	EPSD;PhosphoSitePlus	CCLE	9.140	Down-regulation
AGC_SGK_SGK1_ST	O60343	TBC1D4	O00141	SGK1	T749	S750L	750	Missense	proximal	1	no	12.979	13.037	EPSD	CCLE	9.140	Up-regulation
AGC_SGK_SGK1_ST	O60343	TBC1D4	O00141	SGK1	S751	S750L	750	Missense	proximal	-1	no	20.327	20.237	EPSD;PhosphoSitePlus	CCLE	9.140	Down-regulation
AGC_SGK_SGK1_ST	O60343	TBC1D4	O00141	SGK1	T752	S750L	750	Missense	proximal	-2	no	10.075	9.963	EPSD	CCLE	9.140	Down-regulation
AGC_SGK_SGK1_ST	O60343	TBC1D4	O00141	SGK1	S771	S771F	771	Missense	central	0	yes	10.734	0.000	EPSD	CCLE	9.140	Loss
AGC_SGK_SGK1_ST	Q9UN36	NDRG2	O00141	SGK1	T330	A336S	336	Missense	distal	6	no	17.630	17.636	EPSD;PhosphoSitePlus	CCLE	9.140	Up-regulation
AGC_SGK_SGK1_ST	Q9UN36	NDRG2	O00141	SGK1	S332	A336S	336	Missense	distal	4	no	20.303	20.300	EPSD;PhosphoSitePlus	CCLE	9.140	Down-regulation
AGC_SGK_SGK1_ST	Q9UN36	NDRG2	O00141	SGK1	T334	A336S	336	Missense	proximal	2	no	13.398	13.340	EPSD	CCLE	9.140	Down-regulation
AGC_SGK_SGK1_ST	Q9UN36	NDRG2	O00141	SGK1	T348	R347C	347	Missense	proximal	-1	no	19.728	19.608	PhosphoSitePlus;EPSD	CCLE	9.140	Down-regulation
AGC_SGK_SGK1_ST	Q9UN36	NDRG2	O00141	SGK1	S350	R347C	347	Missense	distal	-3	no	16.482	8.420	EPSD	CCLE	9.140	Loss
AGC_SGK_SGK1_ST	Q9UN36	NDRG2	O00141	SGK1	S352	R347C	347	Missense	distal	-5	no	9.627	3.365	EPSD	CCLE	9.140	Loss
AGC_SGK_SGK1_ST	P10636	MAPT	O00141	SGK1	T167	E161Q	161	Missense	distal	-6	no	10.219	10.247	EPSD	CCLE	9.140	Up-regulation
AGC_SGK_SGK1_ST	P10636	MAPT	O00141	SGK1	T167	P170F	170	Missense	distal	3	no	10.219	9.809	EPSD	CCLE	9.140	Down-regulation
AGC_SGK_SGK1_ST	P10636	MAPT	O00141	SGK1	T167	G174A	174	Missense	distal	7	no	10.219	9.927	EPSD	CCLE	9.140	Down-regulation
AGC_SGK_SGK1_ST	P10636	MAPT	O00141	SGK1	S171	P170F	170	Missense	proximal	-1	no	12.821	12.705	EPSD	CCLE	9.140	Down-regulation
AGC_SGK_SGK1_ST	P10636	MAPT	O00141	SGK1	S171	G174A	174	Missense	distal	3	no	12.821	13.057	EPSD	CCLE	9.140	Up-regulation
AGC_SGK_SGK1_ST	P10636	MAPT	O00141	SGK1	S214	D221Y	221	Missense	distal	7	no	13.460	13.589	PhosphoSitePlus	CCLE	9.140	Up-regulation
AGC_SGK_SGK1_ST	P10636	MAPT	O00141	SGK1	S400	K405R	405	Missense	distal	5	no	9.501	9.469	EPSD	CCLE	9.140	Down-regulation
AGC_SGK_SGK1_ST	P10636	MAPT	O00141	SGK1	T403	K405R	405	Missense	proximal	2	no	10.858	11.304	EPSD	CCLE	9.140	Up-regulation
AGC_SGK_SGK1_ST	P10636	MAPT	O00141	SGK1	S516	R511H	511	Missense	distal	-5	no	12.537	5.205	EPSD	CCLE	9.140	Loss
AGC_SGK_SGK1_ST	P10636	MAPT	O00141	SGK1	S516	G518S	518	Missense	proximal	2	no	12.537	12.211	EPSD	CCLE	9.140	Down-regulation
AGC_SGK_SGK1_ST	P10636	MAPT	O00141	SGK1	T529	R526L	526	Missense	distal	-3	no	11.727	6.378	EPSD	CCLE	9.140	Loss
AGC_SGK_SGK1_ST	P10636	MAPT	O00141	SGK1	S531	R526L	526	Missense	distal	-5	no	17.834	13.607	EPSD	CCLE	9.140	Down-regulation
AGC_SGK_SGK1_ST	P10636	MAPT	O00141	SGK1	T562	R559H	559	Missense	distal	-3	no	11.032	1.414	EPSD	CCLE	9.140	Loss
AGC_SGK_SGK1_ST	P10636	MAPT	O00141	SGK1	S726	S721C	721	Missense	distal	-5	no	13.118	12.101	EPSD	CCLE	9.140	Down-regulation
AGC_SGK_SGK1_ST	P10636	MAPT	O00141	SGK1	S726	H724R	724	Missense	proximal	-2	no	13.118	13.555	EPSD	CCLE	9.140	Up-regulation
AGC_SGK_SGK1_ST	P10636	MAPT	O00141	SGK1	S729	H724R	724	Missense	distal	-5	no	2.947	10.280	EPSD	CCLE	9.140	Gain
AGC_SGK_SGK1_ST	O00141	SGK1	O00141	SGK1	S61	P63F	63	Missense	proximal	2	no	8.753	9.187	EPSD	CCLE	9.140	Gain
AGC_SGK_SGK1_ST	Q9Y2V2	CARHSP1	O00141	SGK1	T50	V55L	55	Missense	distal	5	no	12.625	12.672	EPSD	CCLE	9.140	Up-regulation
AGC_SGK_SGK1_ST	Q9Y2V2	CARHSP1	O00141	SGK1	T50	R47W	47	Missense	distal	-3	no	12.625	2.929	EPSD	CCLE	9.140	Loss
AGC_SGK_SGK1_ST	Q9Y2V2	CARHSP1	O00141	SGK1	S52	V55L	55	Missense	distal	3	no	16.115	16.350	PhosphoSitePlus	CCLE	9.140	Up-regulation
AGC_SGK_SGK1_ST	Q9Y2V2	CARHSP1	O00141	SGK1	S52	R47W	47	Missense	distal	-5	no	16.115	8.457	PhosphoSitePlus	CCLE	9.140	Loss
AGC_SGK_SGK1_ST	Q9Y2V2	CARHSP1	O00141	SGK1	T54	V55L	55	Missense	proximal	1	no	9.750	9.682	EPSD	CCLE	9.140	Down-regulation
AGC_SGK_SGK1_ST	Q9Y2V2	CARHSP1	O00141	SGK1	T54	R47W	47	Missense	distal	-7	no	9.750	10.864	EPSD	CCLE	9.140	Up-regulation
AGC_SGK_SGK1_ST	Q9Y2V2	CARHSP1	O00141	SGK1	S58	V55L	55	Missense	distal	-3	no	5.403	11.774	EPSD	CCLE	9.140	Gain
AGC_SGK_SGK1_ST	Q9H4A3	WNK1	O00141	SGK1	S185	K191N	191	Missense	distal	6	no	9.265	9.131	EPSD	CCLE	9.140	Loss
AGC_SGK_SGK1_ST	Q9H4A3	WNK1	O00141	SGK1	S1105	R1103Q	1103	Missense	proximal	-2	no	16.009	15.556	EPSD	CCLE	9.140	Down-regulation
AGC_SGK_SGK1_ST	Q9H4A3	WNK1	O00141	SGK1	S1108	R1103Q	1103	Missense	distal	-5	no	10.429	2.278	EPSD	CCLE	9.140	Loss
AGC_SGK_SGK1_ST	Q9H4A3	WNK1	O00141	SGK1	S1110	R1103Q	1103	Missense	distal	-7	no	10.760	11.289	EPSD	CCLE	9.140	Up-regulation
AGC_SGK_SGK1_ST	Q9H4A3	WNK1	O00141	SGK1	S1110	R1117C	1117	Missense	distal	7	no	10.760	10.889	EPSD	CCLE	9.140	Up-regulation
AGC_SGK_SGK1_ST	Q9H4A3	WNK1	O00141	SGK1	S1116	R1117C	1117	Missense	proximal	1	no	9.497	9.496	EPSD	CCLE	9.140	Down-regulation
AGC_SGK_SGK1_ST	Q9H4A3	WNK1	O00141	SGK1	S1289	T1286I	1286	Missense	distal	-3	no	12.903	9.708	EPSD	CCLE	9.140	Down-regulation
AGC_SGK_SGK1_ST	Q9H4A3	WNK1	O00141	SGK1	S1805	L1804V	1804	Missense	proximal	-1	no	11.755	11.625	EPSD	CCLE	9.140	Down-regulation
AGC_SGK_SGK1_ST	O43524	FOXO3	O00141	SGK1	S30	R27G	27	Missense	distal	-3	no	9.790	3.234	EPSD	CCLE	9.140	Loss
AGC_SGK_SGK1_ST	O43524	FOXO3	O00141	SGK1	T32	R27G	27	Missense	distal	-5	no	15.657	10.296	EPSD	CCLE	9.140	Down-regulation
AGC_SGK_SGK1_ST	O43524	FOXO3	O00141	SGK1	S181	V188A	188	Missense	distal	7	no	9.936	9.533	EPSD	CCLE	9.140	Down-regulation
AGC_SGK_SGK1_ST	Q96J92	WNK4	O00141	SGK1	S47	G48W	48	Missense	proximal	1	no	18.127	18.102	EPSD	CCLE	9.140	Down-regulation
AGC_SGK_SGK1_ST	Q96J92	WNK4	O00141	SGK1	S1054	E1057A	1057	Missense	distal	3	no	9.145	9.398	EPSD	CCLE	9.140	Up-regulation
AGC_SGK_SGK1_ST	Q96J92	WNK4	O00141	SGK1	S1190	S1183P	1183	Missense	distal	-7	no	19.299	20.203	EPSD;PhosphoSitePlus	CCLE	9.140	Up-regulation
AGC_SGK_SGK1_ST	Q96J92	WNK4	O00141	SGK1	S1190	F1194S	1194	Missense	distal	4	no	19.299	19.742	EPSD;PhosphoSitePlus	CCLE	9.140	Up-regulation
AGC_SGK_SGK1_ST	Q96J92	WNK4	O00141	SGK1	S1201	F1194S	1194	Missense	distal	-7	no	17.787	16.348	PhosphoSitePlus;EPSD	CCLE	9.140	Down-regulation
AGC_SGK_SGK1_ST	Q6R327	RICTOR	O00141	SGK1	S21	V15I	15	Missense	distal	-6	no	19.124	19.199	EPSD	CCLE	9.140	Up-regulation
AGC_SGK_SGK1_ST	Q6R327	RICTOR	O00141	SGK1	S703	D706E	706	Missense	distal	3	no	11.742	11.654	EPSD	CCLE	9.140	Down-regulation
AGC_SGK_SGK1_ST	Q6R327	RICTOR	O00141	SGK1	S1121	K1119E	1119	Missense	proximal	-2	no	9.482	9.184	EPSD	CCLE	9.140	Down-regulation
AGC_SGK_SGK1_ST	Q6R327	RICTOR	O00141	SGK1	S1353	E1349K	1349	Missense	distal	-4	no	9.383	9.933	EPSD	CCLE	9.140	Up-regulation
AGC_SGK_SGK1_ST	O14920	IKBKB	O00141	SGK1	T11	T8R	8	Missense	distal	-3	no	5.648	10.995	EPSD	CCLE	9.140	Gain
AGC_SGK_SGK1_ST	P42858	HTT	O00141	SGK1	S621	S620C	620	Missense	proximal	-1	no	9.218	9.122	EPSD	CCLE	9.140	Loss
AGC_SGK_SGK1_ST	P42858	HTT	O00141	SGK1	S1111	E1114A	1114	Missense	distal	3	no	12.659	12.912	EPSD	CCLE	9.140	Up-regulation
AGC_SGK_SGK1_ST	P42858	HTT	O00141	SGK1	T2455	F2449L	2449	Missense	distal	-6	no	12.258	12.597	EPSD	CCLE	9.140	Up-regulation
TK_Jak_JAK1_Y	Q9Y5X2	SNX8	P23458	JAK1	Y126	M119T	119	Missense	distal	-7	no	14.341	14.494	EPSD;PhosphoSitePlus	CCLE	8.575	Up-regulation
TK_Jak_JAK1_Y	Q9NZQ7	CD274	P23458	JAK1	Y112	M115T	115	Missense	distal	3	no	9.028	9.282	PhosphoSitePlus	CCLE	8.575	Up-regulation
TK_Jak_JAK1_Y	Q9NZQ7	CD274	P23458	JAK1	Y118	M115T	115	Missense	distal	-3	no	9.892	9.135	EPSD	CCLE	8.575	Down-regulation
TK_Jak_JAK1_Y	Q99683	MAP3K5	P23458	JAK1	Y718	S716N	716	Missense	proximal	-2	no	13.321	13.317	PhosphoSitePlus	CCLE	8.575	Down-regulation
Atypical_TAF1_TAF1_ST	P52655	GTF2A1	P21675	TAF1	S316	V320M	320	Missense	distal	4	no	7.437	7.387	EPSD;PhosphoSitePlus	CCLE	2.466	Down-regulation
Atypical_TAF1_TAF1_ST	P52655	GTF2A1	P21675	TAF1	S321	V320M	320	Missense	proximal	-1	no	7.637	7.639	PhosphoSitePlus;EPSD	CCLE	2.466	Up-regulation
Atypical_TAF1_TAF1_ST	Q15545	TAF7	P21675	TAF1	S171	D173H	173	Missense	proximal	2	no	2.788	1.749	EPSD	CCLE	2.466	Loss
Atypical_TAF1_TAF1_ST	Q15545	TAF7	P21675	TAF1	S264	S264L	264	Missense	central	0	yes	7.120	0.000	PhosphoSitePlus	CCLE	2.466	Loss
AGC_MAST_MASTL_MASTL_ST	O43768	ENSA	Q96GX5	MASTL	S67	G68A	68	Missense	proximal	1	no	31.172	30.342	PhosphoSitePlus	CCLE	1.338	Down-regulation
TK_Abl_ABL1_Y	O94875	SORBS2	P00519	ABL1	Y129	Y129H	129	Missense	central	0	yes	8.818	0.000	EPSD	CCLE	7.039	Loss
TK_Abl_ABL1_Y	P04040	CAT	P00519	ABL1	Y231	Y231D	231	Missense	central	0	yes	9.490	0.000	PhosphoSitePlus;EPSD	CCLE	7.039	Loss
TK_Abl_ABL1_Y	Q15746	MYLK	P00519	ABL1	Y231	V228M	228	Missense	distal	-3	no	7.896	7.583	EPSD;PhosphoSitePlus	CCLE	7.039	Down-regulation
TK_Abl_ABL1_Y	Q15746	MYLK	P00519	ABL1	Y792	G790R	790	Missense	proximal	-2	no	8.354	7.903	EPSD;PhosphoSitePlus	CCLE	7.039	Down-regulation
TK_Abl_ABL1_Y	Q15746	MYLK	P00519	ABL1	Y1575	V1582M	1582	Missense	distal	7	no	8.886	8.899	EPSD;PhosphoSitePlus	CCLE	7.039	Up-regulation
TK_Abl_ABL1_Y	P00519	ABL1	P00519	ABL1	Y139	A137T	137	Missense	proximal	-2	no	6.852	7.068	EPSD	CCLE	7.039	Gain
TK_Abl_ABL1_Y	P00519	ABL1	P00519	ABL1	Y185	A179V	179	Missense	distal	-6	no	7.607	7.628	EPSD	CCLE	7.039	Up-regulation
TK_Abl_ABL1_Y	P00519	ABL1	P00519	ABL1	Y226	T224I	224	Missense	proximal	-2	no	7.319	6.824	EPSD	CCLE	7.039	Loss
TK_Abl_ABL1_Y	O15350	TP73	P00519	ABL1	Y99	A100E	100	Missense	proximal	1	no	11.076	9.969	PhosphoSitePlus	CCLE	7.039	Down-regulation
TK_Abl_ABL1_Y	P11274	BCR	P00519	ABL1	Y360	V353M	353	Missense	distal	-7	no	9.495	9.426	EPSD	CCLE	7.039	Down-regulation
TK_Abl_ABL1_Y	P11274	BCR	P00519	ABL1	Y360	S354F	354	Missense	distal	-6	no	9.495	9.294	EPSD	CCLE	7.039	Down-regulation
TK_Abl_ABL1_Y	P11274	BCR	P00519	ABL1	Y360	T358I	358	Missense	proximal	-2	no	9.495	9.000	EPSD	CCLE	7.039	Down-regulation
TK_Abl_ABL1_Y	P19174	PLCG1	P00519	ABL1	Y977	T972I	972	Missense	distal	-5	no	7.677	5.591	EPSD	CCLE	7.039	Loss
TK_Abl_ABL1_Y	P19174	PLCG1	P00519	ABL1	Y1003	L1008F	1008	Missense	distal	5	no	7.294	7.379	PhosphoSitePlus;EPSD	CCLE	7.039	Up-regulation
TK_Abl_ABL1_Y	P42684	ABL2	P00519	ABL1	Y439	A445G	445	Missense	distal	6	no	7.103	6.965	EPSD	CCLE	7.039	Loss
TK_Abl_ABL1_Y	P53350	PLK1	P00519	ABL1	Y582	R581C	581	Missense	proximal	-1	no	5.694	7.648	EPSD	CCLE	7.039	Gain
TK_Abl_ABL1_Y	Q6ZUJ8	PIK3AP1	P00519	ABL1	Y570	F569V	569	Missense	proximal	-1	no	10.002	10.482	PhosphoSitePlus;EPSD	CCLE	7.039	Up-regulation
TK_Abl_ABL1_Y	P09619	PDGFRB	P00519	ABL1	Y579	M585I	585	Missense	distal	6	no	7.429	7.364	EPSD	CCLE	7.039	Down-regulation
TK_Abl_ABL1_Y	P09619	PDGFRB	P00519	ABL1	Y579	G576S	576	Missense	distal	-3	no	7.429	7.655	EPSD	CCLE	7.039	Up-regulation
TK_Abl_ABL1_Y	P09619	PDGFRB	P00519	ABL1	Y581	M585I	585	Missense	distal	4	no	8.600	8.983	EPSD	CCLE	7.039	Up-regulation
TK_Abl_ABL1_Y	P09619	PDGFRB	P00519	ABL1	Y581	G576S	576	Missense	distal	-5	no	8.600	8.949	EPSD	CCLE	7.039	Up-regulation
TK_Abl_ABL1_Y	P09619	PDGFRB	P00519	ABL1	Y589	M585I	585	Missense	distal	-4	no	6.435	7.280	EPSD	CCLE	7.039	Gain
TK_Abl_ABL1_Y	P09619	PDGFRB	P00519	ABL1	Y716	N718Y	718	Missense	proximal	2	no	7.053	6.510	EPSD	CCLE	7.039	Loss
TK_Abl_ABL1_Y	P09619	PDGFRB	P00519	ABL1	Y716	R709C	709	Missense	distal	-7	no	7.053	6.750	EPSD	CCLE	7.039	Loss
TK_Abl_ABL1_Y	P09619	PDGFRB	P00519	ABL1	Y751	S748L	748	Missense	distal	-3	no	7.940	7.285	EPSD	CCLE	7.039	Down-regulation
TK_Abl_ABL1_Y	P09619	PDGFRB	P00519	ABL1	Y771	N777S	777	Missense	distal	6	no	8.867	8.573	EPSD	CCLE	7.039	Down-regulation
TK_Abl_ABL1_Y	P09619	PDGFRB	P00519	ABL1	Y970	K967E	967	Missense	distal	-3	no	7.900	8.927	PhosphoSitePlus;EPSD	CCLE	7.039	Up-regulation
TK_Abl_ABL1_Y	Q14247	CTTN	P00519	ABL1	Y154	F158V	158	Missense	distal	4	no	6.827	7.107	EPSD	CCLE	7.039	Gain
TK_Abl_ABL1_Y	Q9Y6Q9	NCOA3	P00519	ABL1	Y1357	M1362V	1362	Missense	distal	5	no	8.959	9.228	PhosphoSitePlus	CCLE	7.039	Up-regulation
TK_Abl_ABL1_Y	P46108	CRK	P00519	ABL1	Y239	P237S	237	Missense	proximal	-2	no	10.694	11.086	EPSD;PhosphoSitePlus	CCLE	7.039	Up-regulation
TK_Abl_ABL1_Y	Q9Y6N7	ROBO1	P00519	ABL1	Y1038	V1037I	1037	Missense	proximal	-1	no	10.246	12.012	EPSD;PhosphoSitePlus	CCLE	7.039	Up-regulation
TK_Abl_ABL1_Y	Q9Y6N7	ROBO1	P00519	ABL1	Y1114	V1117M	1117	Missense	distal	3	no	8.926	7.919	PhosphoSitePlus;EPSD	CCLE	7.039	Down-regulation
TK_Abl_ABL1_Y	Q9Y6N7	ROBO1	P00519	ABL1	Y1114	V1112I	1112	Missense	proximal	-2	no	8.926	8.189	PhosphoSitePlus;EPSD	CCLE	7.039	Down-regulation
TK_Abl_ABL1_Y	Q9Y6N7	ROBO1	P00519	ABL1	Y1114	V1109M	1109	Missense	distal	-5	no	8.926	8.086	PhosphoSitePlus;EPSD	CCLE	7.039	Down-regulation
TK_Abl_ABL1_Y	Q9Y6N7	ROBO1	P00519	ABL1	Y1587	T1594I	1594	Missense	distal	7	no	8.352	8.277	EPSD	CCLE	7.039	Down-regulation
TK_Abl_ABL1_Y	Q9Y6N7	ROBO1	P00519	ABL1	Y1587	T1591S	1591	Missense	distal	4	no	8.352	8.151	EPSD	CCLE	7.039	Down-regulation
TK_Abl_ABL1_Y	Q9Y6N7	ROBO1	P00519	ABL1	Y1587	P1590H	1590	Missense	distal	3	no	8.352	5.136	EPSD	CCLE	7.039	Loss
TK_Abl_ABL1_Y	Q9Y6N7	ROBO1	P00519	ABL1	Y1587	I1584T	1584	Missense	distal	-3	no	8.352	8.116	EPSD	CCLE	7.039	Down-regulation
TK_Abl_ABL1_Y	P49023	PXN	P00519	ABL1	Y181	S178N	178	Missense	distal	-3	no	7.226	7.198	EPSD	CCLE	7.039	Down-regulation
TK_Abl_ABL1_Y	P49023	PXN	P00519	ABL1	Y404	P403L	403	Missense	proximal	-1	no	7.343	7.235	EPSD	CCLE	7.039	Down-regulation
TK_Abl_ABL1_Y	P15498	VAV1	P00519	ABL1	Y826	W821C	821	Missense	distal	-5	no	6.767	7.244	EPSD	CCLE	7.039	Gain
TK_Abl_ABL1_Y	P17844	DDX5	P00519	ABL1	Y59	P52L	52	Missense	distal	-7	no	7.456	7.266	EPSD	CCLE	7.039	Down-regulation
TK_Abl_ABL1_Y	P17275	JUNB	P00519	ABL1	Y182	V181I	181	Missense	proximal	-1	no	6.711	8.477	EPSD;PhosphoSitePlus	CCLE	7.039	Gain
TK_Abl_ABL1_Y	P17275	JUNB	P00519	ABL1	Y188	V181I	181	Missense	distal	-7	no	7.733	7.194	PhosphoSitePlus;EPSD	CCLE	7.039	Down-regulation
TK_Abl_ABL1_Y	O14818	PSMA7	P00519	ABL1	Y153	Y153C	153	Missense	central	0	yes	11.538	0.000	PhosphoSitePlus;EPSD	CCLE	7.039	Loss
TK_Abl_ABL1_Y	P46527	CDKN1B	P00519	ABL1	Y88	F87L	87	Missense	proximal	-1	no	9.490	10.278	EPSD;PhosphoSitePlus	CCLE	7.039	Up-regulation
TK_Abl_ABL1_Y	P46527	CDKN1B	P00519	ABL1	Y88	Y89C	89	Missense	proximal	1	no	9.490	8.237	EPSD;PhosphoSitePlus	CCLE	7.039	Down-regulation
TK_Abl_ABL1_Y	P46527	CDKN1B	P00519	ABL1	Y89	F87L	87	Missense	proximal	-2	no	10.249	11.318	PhosphoSitePlus;EPSD	CCLE	7.039	Up-regulation
TK_Abl_ABL1_Y	P46527	CDKN1B	P00519	ABL1	Y89	Y89C	89	Missense	central	0	yes	10.249	0.000	PhosphoSitePlus;EPSD	CCLE	7.039	Loss
TK_Abl_ABL1_Y	P06400	RB1	P00519	ABL1	Y606	P609H	609	Missense	distal	3	no	9.160	5.944	EPSD	CCLE	7.039	Loss
TK_Abl_ABL1_Y	Q00987	MDM2	P00519	ABL1	Y394	S400N	400	Missense	distal	6	no	10.889	11.182	PhosphoSitePlus;EPSD	CCLE	7.039	Up-regulation
TK_Abl_ABL1_Y	Q00987	MDM2	P00519	ABL1	Y405	S400N	400	Missense	distal	-5	no	8.088	7.536	EPSD;PhosphoSitePlus	CCLE	7.039	Down-regulation
TK_Abl_ABL1_Y	P17931	LGALS3	P00519	ABL1	Y107	P106S	106	Missense	proximal	-1	no	10.453	8.863	EPSD;PhosphoSitePlus	CCLE	7.039	Down-regulation
TK_Abl_ABL1_Y	P43403	ZAP70	P00519	ABL1	Y597	R592C	592	Missense	distal	-5	no	9.155	7.099	EPSD	CCLE	7.039	Down-regulation
TK_Abl_ABL1_Y	P43403	ZAP70	P00519	ABL1	Y598	R592C	592	Missense	distal	-6	no	7.684	7.473	EPSD	CCLE	7.039	Down-regulation
TK_Abl_ABL1_Y	P15391	CD19	P00519	ABL1	Y378	D384E	384	Missense	distal	6	no	7.896	8.041	EPSD	CCLE	7.039	Up-regulation
TK_Abl_ABL1_Y	Q99638	RAD9A	P00519	ABL1	Y28	D34E	34	Missense	distal	6	no	7.846	7.991	PhosphoSitePlus	CCLE	7.039	Up-regulation
TK_Abl_ABL1_Y	O15269	SPTLC1	P00519	ABL1	Y18	L17F	17	Missense	proximal	-1	no	7.111	6.323	EPSD	CCLE	7.039	Loss
TK_Abl_ABL1_Y	O15269	SPTLC1	P00519	ABL1	Y164	T158A	158	Missense	distal	-6	no	8.622	8.634	PhosphoSitePlus	CCLE	7.039	Up-regulation
TK_Abl_ABL1_Y	Q92769	HDAC2	P00519	ABL1	Y55	A62V	62	Missense	distal	7	no	7.185	7.218	EPSD	CCLE	7.039	Up-regulation
TK_Abl_ABL1_Y	Q92769	HDAC2	P00519	ABL1	Y55	I54T	54	Missense	proximal	-1	no	7.185	5.268	EPSD	CCLE	7.039	Loss
TK_Abl_ABL1_Y	Q92769	HDAC2	P00519	ABL1	Y68	A62V	62	Missense	distal	-6	no	7.646	7.667	EPSD	CCLE	7.039	Up-regulation
TK_Abl_ABL1_Y	Q92769	HDAC2	P00519	ABL1	Y88	K90E	90	Missense	proximal	2	no	7.312	7.295	EPSD	CCLE	7.039	Down-regulation
TK_Abl_ABL1_Y	Q92769	HDAC2	P00519	ABL1	Y88	M85I	85	Missense	distal	-3	no	7.312	7.714	EPSD	CCLE	7.039	Up-regulation
TK_Abl_ABL1_Y	Q92769	HDAC2	P00519	ABL1	Y222	I215V	215	Missense	distal	-7	no	6.757	7.296	PhosphoSitePlus	CCLE	7.039	Gain
TK_Abl_ABL1_Y	Q14847	LASP1	P00519	ABL1	Y171	Q172E	172	Missense	proximal	1	no	10.568	10.804	PhosphoSitePlus	CCLE	7.039	Up-regulation
TK_Abl_ABL1_Y	P42768	WAS	P00519	ABL1	Y102	W97Y	97	Missense	distal	-5	no	7.430	8.907	EPSD	CCLE	7.039	Up-regulation
TK_Abl_ABL1_Y	P42768	WAS	P00519	ABL1	Y102	Y107C	107	Missense	distal	5	no	7.430	7.765	EPSD	CCLE	7.039	Up-regulation
TK_Abl_ABL1_Y	P11387	TOP1	P00519	ABL1	Y268	T270A	270	Missense	proximal	2	no	10.618	10.811	PhosphoSitePlus	CCLE	7.039	Up-regulation
TK_Abl_ABL1_Y	P11387	TOP1	P00519	ABL1	Y537	N539K	539	Missense	proximal	2	no	7.140	6.622	EPSD	CCLE	7.039	Loss
Other_CDC7_CDC7_ST	P19338	NCL	O00311	CDC7	T76	V72I	72	Missense	distal	-4	no	81.375	80.606	EPSD;PhosphoSitePlus	CCLE	65.097	Down-regulation
Other_CDC7_CDC7_ST	P19338	NCL	O00311	CDC7	S206	E203K	203	Missense	distal	-3	no	77.704	77.914	EPSD	CCLE	65.097	Up-regulation
Other_CDC7_CDC7_ST	P55081	MFAP1	O00311	CDC7	S179	E186G	186	Missense	distal	7	no	71.787	73.049	EPSD	CCLE	65.097	Up-regulation
Other_CDC7_CDC7_ST	P49736	MCM2	O00311	CDC7	S139	R133C	133	Missense	distal	-6	no	81.331	80.614	EPSD;PhosphoSitePlus	CCLE	65.097	Down-regulation
Other_CDC7_CDC7_ST	P49736	MCM2	O00311	CDC7	S139	R133P	133	Missense	distal	-6	no	81.331	81.439	EPSD;PhosphoSitePlus	CCLE	65.097	Up-regulation
Other_CDC7_CDC7_ST	P49736	MCM2	O00311	CDC7	S139	D143N	143	Missense	distal	4	no	81.331	81.675	EPSD;PhosphoSitePlus	CCLE	65.097	Up-regulation
Other_CDC7_CDC7_ST	P49736	MCM2	O00311	CDC7	S381	G383D	383	Missense	proximal	2	no	73.894	72.636	EPSD	CCLE	65.097	Down-regulation
Other_CDC7_CDC7_ST	P49736	MCM2	O00311	CDC7	S566	S566N	566	Missense	central	0	yes	66.076	0.000	EPSD	CCLE	65.097	Loss
Other_CDC7_CDC7_ST	O00311	CDC7	O00311	CDC7	S239	K235T	235	Missense	distal	-4	no	73.820	73.716	EPSD;PhosphoSitePlus	CCLE	65.097	Down-regulation
Other_CDC7_CDC7_ST	O00311	CDC7	O00311	CDC7	S277	G276R	276	Missense	proximal	-1	no	89.579	89.357	EPSD;PhosphoSitePlus	CCLE	65.097	Down-regulation
Other_CDC7_CDC7_ST	O00311	CDC7	O00311	CDC7	S285	F292L	292	Missense	distal	7	no	76.028	76.360	EPSD;PhosphoSitePlus	CCLE	65.097	Up-regulation
Other_CDC7_CDC7_ST	O00311	CDC7	O00311	CDC7	S296	F292L	292	Missense	distal	-4	no	79.325	78.457	EPSD;PhosphoSitePlus	CCLE	65.097	Down-regulation
Other_CDC7_CDC7_ST	O00311	CDC7	O00311	CDC7	S297	F292L	292	Missense	distal	-5	no	77.322	78.240	EPSD;PhosphoSitePlus	CCLE	65.097	Up-regulation
Other_CDC7_CDC7_ST	Q9HAW4	CLSPN	O00311	CDC7	S110	K117R	117	Missense	distal	7	no	100.627	101.468	EPSD;PhosphoSitePlus	CCLE	65.097	Up-regulation
Other_CDC7_CDC7_ST	Q9HAW4	CLSPN	O00311	CDC7	S235	N242S	242	Missense	distal	7	no	66.357	66.852	EPSD	CCLE	65.097	Up-regulation
Other_CDC7_CDC7_ST	Q9HAW4	CLSPN	O00311	CDC7	S704	K697T	697	Missense	distal	-7	no	79.769	82.185	EPSD;PhosphoSitePlus	CCLE	65.097	Up-regulation
Other_CDC7_CDC7_ST	Q9HAW4	CLSPN	O00311	CDC7	S744	S744P	744	Missense	central	0	yes	76.867	0.000	EPSD;PhosphoSitePlus	CCLE	65.097	Loss
Other_CDC7_CDC7_ST	Q9HAW4	CLSPN	O00311	CDC7	T746	S744P	744	Missense	proximal	-2	no	69.867	71.085	EPSD	CCLE	65.097	Up-regulation
Other_CDC7_CDC7_ST	Q9HAW4	CLSPN	O00311	CDC7	S968	G971S	971	Missense	distal	3	no	69.915	70.206	EPSD	CCLE	65.097	Up-regulation
Other_CDC7_CDC7_ST	Q9HAW4	CLSPN	O00311	CDC7	S1147	M1149T	1149	Missense	proximal	2	no	74.085	74.507	EPSD;PhosphoSitePlus	CCLE	65.097	Up-regulation
Other_CDC7_CDC7_ST	P11388	TOP2A	O00311	CDC7	S1391	P1394R	1394	Missense	distal	3	no	69.016	69.260	EPSD	CCLE	65.097	Up-regulation
Other_CDC7_CDC7_ST	P11388	TOP2A	O00311	CDC7	S1474	I1481N	1481	Missense	distal	7	no	73.997	73.750	EPSD	CCLE	65.097	Down-regulation
Other_CDC7_CDC7_ST	Q9UBU7	DBF4	O00311	CDC7	T273	K268N	268	Missense	distal	-5	no	80.590	84.086	EPSD;PhosphoSitePlus	CCLE	65.097	Up-regulation
Other_CDC7_CDC7_ST	P06748	NPM1	O00311	CDC7	S137	K141R	141	Missense	distal	4	no	78.837	78.592	PhosphoSitePlus;EPSD	CCLE	65.097	Down-regulation
Other_CDC7_CDC7_ST	O75475	PSIP1	O00311	CDC7	S62	K65M	65	Missense	distal	3	no	70.397	70.117	EPSD	CCLE	65.097	Down-regulation
CMGC_MAPK_JNK_MAPK8_ST	Q01844	EWSR1	P45983-2	MAPK8	T79	T75I	75	Missense	distal	-4	no	7.669	7.242	PhosphoSitePlus	CCLE	2.638	Down-regulation
CMGC_GSK_GSK3B_ST	Q13131	PRKAA1	P49841	GSK3B	S356	S356N	356	Missense	central	0	yes	10.303	0.000	EPSD	CCLE	6.007	Loss
CMGC_GSK_GSK3B_ST	Q13131	PRKAA1	P49841	GSK3B	T490	S494L	494	Missense	distal	4	no	11.524	8.806	PhosphoSitePlus;EPSD	CCLE	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	Q13131	PRKAA1	P49841	GSK3B	T490	S494W	494	Missense	distal	4	no	11.524	7.575	PhosphoSitePlus;EPSD	CCLE	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	Q13131	PRKAA1	P49841	GSK3B	S520	L521V	521	Missense	proximal	1	no	8.064	7.934	EPSD	CCLE	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	Q13131	PRKAA1	P49841	GSK3B	S524	L521V	521	Missense	distal	-3	no	5.999	6.157	EPSD	CCLE	6.007	Gain
CMGC_GSK_GSK3B_ST	Q13131	PRKAA1	P49841	GSK3B	T526	L521V	521	Missense	distal	-5	no	6.927	7.398	EPSD	CCLE	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	Q13131	PRKAA1	P49841	GSK3B	S527	L521V	521	Missense	distal	-6	no	7.544	7.478	EPSD	CCLE	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	P11388	TOP2A	P49841	GSK3B	S1387	P1394R	1394	Missense	distal	7	no	6.530	7.031	EPSD	CCLE	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	P11388	TOP2A	P49841	GSK3B	S1393	P1394R	1394	Missense	proximal	1	no	7.378	5.058	EPSD	CCLE	6.007	Loss
CMGC_GSK_GSK3B_ST	P11388	TOP2A	P49841	GSK3B	T1487	I1481N	1481	Missense	distal	-6	no	5.993	6.054	EPSD	CCLE	6.007	Gain
CMGC_GSK_GSK3B_ST	P36956	SREBF1	P49841	GSK3B	T59	A62V	62	Missense	distal	3	no	7.415	7.544	EPSD	CCLE	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	P36956	SREBF1	P49841	GSK3B	S63	A62V	62	Missense	proximal	-1	no	11.097	11.300	EPSD	CCLE	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	P36956	SREBF1	P49841	GSK3B	T426	E422D	422	Missense	distal	-4	no	10.176	10.173	EPSD;PhosphoSitePlus	CCLE	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	P36956	SREBF1	P49841	GSK3B	S453	S448N	448	Missense	distal	-5	no	9.040	8.747	EPSD	CCLE	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	P10636	MAPT	P49841	GSK3B	S68	A66V	66	Missense	proximal	-2	no	6.933	7.235	EPSD	CCLE	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	P10636	MAPT	P49841	GSK3B	T69	A66V	66	Missense	distal	-3	no	6.768	6.914	EPSD	CCLE	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	P10636	MAPT	P49841	GSK3B	T111	G107V	107	Missense	distal	-4	no	8.413	7.608	EPSD	CCLE	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	P10636	MAPT	P49841	GSK3B	T167	E161Q	161	Missense	distal	-6	no	7.072	7.130	EPSD	CCLE	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	P10636	MAPT	P49841	GSK3B	T167	P170F	170	Missense	distal	3	no	7.072	6.844	EPSD	CCLE	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	P10636	MAPT	P49841	GSK3B	T167	G174A	174	Missense	distal	7	no	7.072	7.400	EPSD	CCLE	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	P10636	MAPT	P49841	GSK3B	S171	P170F	170	Missense	proximal	-1	no	6.238	6.052	EPSD	CCLE	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	P10636	MAPT	P49841	GSK3B	S171	G174A	174	Missense	distal	3	no	6.238	5.858	EPSD	CCLE	6.007	Loss
CMGC_GSK_GSK3B_ST	P10636	MAPT	P49841	GSK3B	S228	D221Y	221	Missense	distal	-7	no	11.620	11.646	EPSD	CCLE	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	P10636	MAPT	P49841	GSK3B	S228	P234S	234	Missense	distal	6	no	11.620	11.618	EPSD	CCLE	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	P10636	MAPT	P49841	GSK3B	S232	P234S	234	Missense	proximal	2	no	6.264	5.821	EPSD	CCLE	6.007	Loss
CMGC_GSK_GSK3B_ST	P10636	MAPT	P49841	GSK3B	S238	P234S	234	Missense	distal	-4	no	7.281	7.844	EPSD	CCLE	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	P10636	MAPT	P49841	GSK3B	S238	D242H	242	Missense	distal	4	no	7.281	5.948	EPSD	CCLE	6.007	Loss
CMGC_GSK_GSK3B_ST	P10636	MAPT	P49841	GSK3B	S438	V442I	442	Missense	distal	4	no	6.877	5.945	EPSD	CCLE	6.007	Loss
CMGC_GSK_GSK3B_ST	P10636	MAPT	P49841	GSK3B	S447	V442I	442	Missense	distal	-5	no	9.392	9.285	EPSD	CCLE	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	P10636	MAPT	P49841	GSK3B	S508	R511H	511	Missense	distal	3	no	6.264	6.606	EPSD	CCLE	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	P10636	MAPT	P49841	GSK3B	S512	R511H	511	Missense	proximal	-1	no	6.640	6.726	EPSD	CCLE	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	P10636	MAPT	P49841	GSK3B	S512	G518S	518	Missense	distal	6	no	6.640	6.644	EPSD	CCLE	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	P10636	MAPT	P49841	GSK3B	S515	R511H	511	Missense	distal	-4	no	7.219	7.318	EPSD	CCLE	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	P10636	MAPT	P49841	GSK3B	S515	G518S	518	Missense	distal	3	no	7.219	7.175	EPSD	CCLE	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	P10636	MAPT	P49841	GSK3B	S516	R511H	511	Missense	distal	-5	no	7.391	6.861	EPSD	CCLE	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	P10636	MAPT	P49841	GSK3B	S516	G518S	518	Missense	proximal	2	no	7.391	7.650	EPSD	CCLE	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	P10636	MAPT	P49841	GSK3B	S519	G518S	518	Missense	proximal	-1	no	7.994	7.987	EPSD	CCLE	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	P10636	MAPT	P49841	GSK3B	S519	R526L	526	Missense	distal	7	no	7.994	7.542	EPSD	CCLE	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	P10636	MAPT	P49841	GSK3B	T522	G518S	518	Missense	distal	-4	no	6.333	6.762	EPSD	CCLE	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	P10636	MAPT	P49841	GSK3B	T522	R526L	526	Missense	distal	4	no	6.333	6.653	EPSD	CCLE	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	P10636	MAPT	P49841	GSK3B	S525	G518S	518	Missense	distal	-7	no	8.083	8.085	EPSD	CCLE	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	P10636	MAPT	P49841	GSK3B	S525	R526L	526	Missense	proximal	1	no	8.083	7.542	EPSD	CCLE	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	P10636	MAPT	P49841	GSK3B	S527	R526L	526	Missense	proximal	-1	no	7.147	7.209	EPSD	CCLE	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	P10636	MAPT	P49841	GSK3B	T529	R526L	526	Missense	distal	-3	no	6.762	6.603	EPSD	CCLE	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	P10636	MAPT	P49841	GSK3B	S531	R526L	526	Missense	distal	-5	no	8.534	7.945	EPSD	CCLE	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	P10636	MAPT	P49841	GSK3B	S552	R559H	559	Missense	distal	7	no	7.533	7.721	EPSD	CCLE	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	P10636	MAPT	P49841	GSK3B	S558	R559H	559	Missense	proximal	1	no	6.704	5.323	EPSD	CCLE	6.007	Loss
CMGC_GSK_GSK3B_ST	P10636	MAPT	P49841	GSK3B	S575	K574N	574	Missense	proximal	-1	no	7.105	7.112	EPSD	CCLE	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	P10636	MAPT	P49841	GSK3B	S637	D631E	631	Missense	distal	-6	no	7.884	7.847	EPSD	CCLE	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	P10636	MAPT	P49841	GSK3B	S713	G706V	706	Missense	distal	-7	no	9.598	9.621	EPSD	CCLE	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	P10636	MAPT	P49841	GSK3B	S713	S717C	717	Missense	distal	4	no	9.598	3.465	EPSD	CCLE	6.007	Loss
CMGC_GSK_GSK3B_ST	P10636	MAPT	P49841	GSK3B	S717	S717C	717	Missense	central	0	yes	9.078	0.000	EPSD	CCLE	6.007	Loss
CMGC_GSK_GSK3B_ST	P10636	MAPT	P49841	GSK3B	S717	S721C	721	Missense	distal	4	no	9.078	2.945	EPSD	CCLE	6.007	Loss
CMGC_GSK_GSK3B_ST	P10636	MAPT	P49841	GSK3B	S717	H724R	724	Missense	distal	7	no	9.078	8.890	EPSD	CCLE	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	P10636	MAPT	P49841	GSK3B	S721	S717C	717	Missense	distal	-4	no	9.949	7.834	EPSD	CCLE	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	P10636	MAPT	P49841	GSK3B	S721	S721C	721	Missense	central	0	yes	9.949	0.000	EPSD	CCLE	6.007	Loss
CMGC_GSK_GSK3B_ST	P10636	MAPT	P49841	GSK3B	S721	H724R	724	Missense	distal	3	no	9.949	9.606	EPSD	CCLE	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	P10636	MAPT	P49841	GSK3B	S729	H724R	724	Missense	distal	-5	no	5.680	6.211	EPSD	CCLE	6.007	Gain
CMGC_GSK_GSK3B_ST	P10636	MAPT	P49841	GSK3B	S739	Q741K	741	Missense	proximal	2	no	8.627	8.357	EPSD	CCLE	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	Q13541	EIF4EBP1	P49841	GSK3B	S65	P66H	66	Missense	proximal	1	no	7.228	3.528	PhosphoSitePlus;EPSD	CCLE	6.007	Loss
CMGC_GSK_GSK3B_ST	Q13541	EIF4EBP1	P49841	GSK3B	S101	R99C	99	Missense	proximal	-2	no	6.885	6.689	EPSD	CCLE	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	P50895	BCAM	P49841	GSK3B	S206	S206R	206	Missense	central	0	yes	6.864	0.000	EPSD	CCLE	6.007	Loss
CMGC_GSK_GSK3B_ST	P50895	BCAM	P49841	GSK3B	S541	Q543K	543	Missense	proximal	2	no	9.231	8.961	EPSD	CCLE	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	P50895	BCAM	P49841	GSK3B	S541	A547T	547	Missense	distal	6	no	9.231	9.235	EPSD	CCLE	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	P50895	BCAM	P49841	GSK3B	S596	P590S	590	Missense	distal	-6	no	6.700	6.679	PhosphoSitePlus	CCLE	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	P50895	BCAM	P49841	GSK3B	S596	H597Y	597	Missense	proximal	1	no	6.700	7.082	PhosphoSitePlus	CCLE	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	P50895	BCAM	P49841	GSK3B	S596	S600P	600	Missense	distal	4	no	6.700	3.729	PhosphoSitePlus	CCLE	6.007	Loss
CMGC_GSK_GSK3B_ST	P50895	BCAM	P49841	GSK3B	S596	S600L	600	Missense	distal	4	no	6.700	3.982	PhosphoSitePlus	CCLE	6.007	Loss
CMGC_GSK_GSK3B_ST	Q9UPN3	MACF1	P49841	GSK3B	T334	T341S	341	Missense	distal	7	no	6.277	6.336	EPSD	CCLE	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	Q9UPN3	MACF1	P49841	GSK3B	S814	N818S	818	Missense	distal	4	no	3.766	7.376	EPSD	CCLE	6.007	Gain
CMGC_GSK_GSK3B_ST	Q9UPN3	MACF1	P49841	GSK3B	S1363	Y1357C	1357	Missense	distal	-6	no	7.336	7.410	EPSD	CCLE	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	Q9UPN3	MACF1	P49841	GSK3B	S2078	E2073Q	2073	Missense	distal	-5	no	6.192	5.904	EPSD	CCLE	6.007	Loss
CMGC_GSK_GSK3B_ST	Q9UPN3	MACF1	P49841	GSK3B	S4415	S4415P	4415	Missense	central	0	yes	7.201	0.000	EPSD	CCLE	6.007	Loss
CMGC_GSK_GSK3B_ST	Q9UPN3	MACF1	P49841	GSK3B	S4496	M4491V	4491	Missense	distal	-5	no	9.264	9.542	EPSD	CCLE	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	Q9UPN3	MACF1	P49841	GSK3B	S5588	E5583K	5583	Missense	distal	-5	no	6.548	6.318	EPSD	CCLE	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	Q9UPN3	MACF1	P49841	GSK3B	S5588	P5593S	5593	Missense	distal	5	no	6.548	5.594	EPSD	CCLE	6.007	Loss
CMGC_GSK_GSK3B_ST	Q9UPN3	MACF1	P49841	GSK3B	S5592	P5593S	5593	Missense	proximal	1	no	8.862	5.017	EPSD	CCLE	6.007	Loss
CMGC_GSK_GSK3B_ST	Q9UPN3	MACF1	P49841	GSK3B	S7226	R7227Q	7227	Missense	proximal	1	no	8.824	7.876	EPSD;PhosphoSitePlus	CCLE	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	Q9UPN3	MACF1	P49841	GSK3B	S7226	R7233H	7233	Missense	distal	7	no	8.824	9.012	EPSD;PhosphoSitePlus	CCLE	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	Q9UPN3	MACF1	P49841	GSK3B	S7230	R7227Q	7227	Missense	distal	-3	no	9.895	9.756	EPSD;PhosphoSitePlus	CCLE	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	Q9UPN3	MACF1	P49841	GSK3B	S7230	R7233H	7233	Missense	distal	3	no	9.895	10.237	EPSD;PhosphoSitePlus	CCLE	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	Q9UPN3	MACF1	P49841	GSK3B	S7247	M7248I	7248	Missense	proximal	1	no	6.704	6.409	EPSD	CCLE	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	Q9UPN3	MACF1	P49841	GSK3B	S7251	M7248I	7248	Missense	distal	-3	no	7.910	8.052	EPSD	CCLE	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	Q9UPN3	MACF1	P49841	GSK3B	T7254	M7248I	7248	Missense	distal	-6	no	6.672	6.662	EPSD	CCLE	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	Q9UPN3	MACF1	P49841	GSK3B	S7288	N7289S	7289	Missense	proximal	1	no	6.117	7.792	EPSD	CCLE	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	Q9UPN3	MACF1	P49841	GSK3B	S7291	N7289S	7289	Missense	proximal	-2	no	6.910	7.139	EPSD	CCLE	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	Q9UPN3	MACF1	P49841	GSK3B	S7292	N7289S	7289	Missense	distal	-3	no	11.477	11.571	EPSD	CCLE	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	Q9UPN3	MACF1	P49841	GSK3B	S7310	P7312S	7312	Missense	proximal	2	no	8.655	8.211	EPSD;PhosphoSitePlus	CCLE	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	Q9UPN3	MACF1	P49841	GSK3B	S7314	P7312S	7312	Missense	proximal	-2	no	10.462	10.206	EPSD;PhosphoSitePlus	CCLE	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	Q9UPN3	MACF1	P49841	GSK3B	S7318	P7312S	7312	Missense	distal	-6	no	8.526	8.505	EPSD;PhosphoSitePlus	CCLE	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	Q9UPN3	MACF1	P49841	GSK3B	T7376	S7380Y	7380	Missense	distal	4	no	7.073	3.560	EPSD	CCLE	6.007	Loss
CMGC_GSK_GSK3B_ST	Q9UPN3	MACF1	P49841	GSK3B	S7380	S7380Y	7380	Missense	central	0	yes	7.336	0.000	EPSD	CCLE	6.007	Loss
CMGC_GSK_GSK3B_ST	Q9UPN3	MACF1	P49841	GSK3B	S7380	P7386L	7386	Missense	distal	6	no	7.336	7.329	EPSD	CCLE	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	Q00653	NFKB2	P49841	GSK3B	T810	S814G	814	Missense	distal	4	no	6.596	3.353	EPSD	CCLE	6.007	Loss
CMGC_GSK_GSK3B_ST	Q00653	NFKB2	P49841	GSK3B	S812	S814G	814	Missense	proximal	2	no	10.832	10.574	EPSD	CCLE	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	Q00653	NFKB2	P49841	GSK3B	S814	S814G	814	Missense	central	0	yes	6.181	0.000	EPSD	CCLE	6.007	Loss
CMGC_GSK_GSK3B_ST	Q00653	NFKB2	P49841	GSK3B	S816	S814G	814	Missense	proximal	-2	no	6.677	6.560	EPSD	CCLE	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	Q00653	NFKB2	P49841	GSK3B	S866	D865N	865	Missense	proximal	-1	no	7.534	7.656	EPSD	CCLE	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	Q00653	NFKB2	P49841	GSK3B	S866	A867V	867	Missense	proximal	1	no	7.534	8.276	EPSD	CCLE	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	P58012	FOXL2	P49841	GSK3B	S326	P333L	333	Missense	distal	7	no	7.202	7.251	EPSD	CCLE	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	Q14449	GRB14	P49841	GSK3B	S358	G356D	356	Missense	proximal	-2	no	8.048	8.150	EPSD;PhosphoSitePlus	CCLE	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	Q14449	GRB14	P49841	GSK3B	S358	Y354H	354	Missense	distal	-4	no	8.048	7.761	EPSD;PhosphoSitePlus	CCLE	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	Q14449	GRB14	P49841	GSK3B	S362	G356D	356	Missense	distal	-6	no	8.428	8.387	PhosphoSitePlus;EPSD	CCLE	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	P49768	PSEN1	P49841	GSK3B	S353	S346R	346	Missense	distal	-7	no	7.747	7.765	PhosphoSitePlus;EPSD	CCLE	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	Q6PGQ7	BORA	P49841	GSK3B	S183	P184H	184	Missense	proximal	1	no	6.500	2.799	EPSD	CCLE	6.007	Loss
CMGC_GSK_GSK3B_ST	Q6PGQ7	BORA	P49841	GSK3B	S304	S308P	308	Missense	distal	4	no	6.567	3.596	EPSD	CCLE	6.007	Loss
CMGC_GSK_GSK3B_ST	P19793	RXRA	P49841	GSK3B	S21	R25Q	25	Missense	distal	4	no	6.940	6.414	EPSD	CCLE	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	P19793	RXRA	P49841	GSK3B	S49	S52I	52	Missense	distal	3	no	9.069	8.648	PhosphoSitePlus;EPSD	CCLE	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	P19793	RXRA	P49841	GSK3B	S78	M77I	77	Missense	proximal	-1	no	7.260	7.161	EPSD;PhosphoSitePlus	CCLE	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	P19793	RXRA	P49841	GSK3B	T82	M77I	77	Missense	distal	-5	no	6.834	7.005	EPSD	CCLE	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	P05412	JUN	P49841	GSK3B	S58	R54G	54	Missense	distal	-4	no	6.002	6.761	EPSD	CCLE	6.007	Gain
CMGC_GSK_GSK3B_ST	Q9UMX1	SUFU	P49841	GSK3B	S342	D338H	338	Missense	distal	-4	no	7.675	7.188	PhosphoSitePlus	CCLE	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	P03372	ESR1	P49841	GSK3B	S102	F97S	97	Missense	distal	-5	no	9.469	8.910	PhosphoSitePlus;EPSD	CCLE	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	O95271	TNKS	P49841	GSK3B	T44	L39V	39	Missense	distal	-5	no	5.597	6.068	EPSD	CCLE	6.007	Gain
CMGC_GSK_GSK3B_ST	O75925	PIAS1	P49841	GSK3B	S328	V331G	331	Missense	distal	3	no	5.999	6.251	EPSD	CCLE	6.007	Gain
CMGC_GSK_GSK3B_ST	O75925	PIAS1	P49841	GSK3B	S485	C481Y	481	Missense	distal	-4	no	5.390	6.704	EPSD	CCLE	6.007	Gain
CMGC_GSK_GSK3B_ST	O75925	PIAS1	P49841	GSK3B	S522	L523R	523	Missense	proximal	1	no	6.003	6.544	EPSD	CCLE	6.007	Gain
CMGC_GSK_GSK3B_ST	Q8NHW3	MAFA	P49841	GSK3B	S49	P54S	54	Missense	distal	5	no	8.896	7.942	EPSD;PhosphoSitePlus	CCLE	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	Q8NHW3	MAFA	P49841	GSK3B	T53	P54S	54	Missense	proximal	1	no	11.257	7.412	EPSD;PhosphoSitePlus	CCLE	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	Q8NHW3	MAFA	P49841	GSK3B	T57	P54S	54	Missense	distal	-3	no	9.242	9.359	EPSD;PhosphoSitePlus	CCLE	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	Q8NHW3	MAFA	P49841	GSK3B	S61	P66S	66	Missense	distal	5	no	9.476	8.522	PhosphoSitePlus;EPSD	CCLE	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	Q8NHW3	MAFA	P49841	GSK3B	S61	P54S	54	Missense	distal	-7	no	9.476	9.478	PhosphoSitePlus;EPSD	CCLE	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	P0DMV8	HSPA1A	P49841	GSK3B	T430	N434S	434	Missense	distal	4	no	2.966	6.577	EPSD	CCLE	6.007	Gain
CMGC_GSK_GSK3B_ST	Q14596	NBR1	P49841	GSK3B	S123	V118L	118	Missense	distal	-5	no	7.385	6.914	EPSD	CCLE	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	Q14596	NBR1	P49841	GSK3B	T581	V585M	585	Missense	distal	4	no	6.430	6.586	EPSD	CCLE	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	Q14596	NBR1	P49841	GSK3B	T586	V585M	585	Missense	proximal	-1	no	10.220	10.121	PhosphoSitePlus	CCLE	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	Q14596	NBR1	P49841	GSK3B	S590	V585M	585	Missense	distal	-5	no	6.747	6.469	EPSD	CCLE	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	P12036	NEFH	P49841	GSK3B	S57	S63G	63	Missense	distal	6	no	7.937	7.933	EPSD	CCLE	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	P12036	NEFH	P49841	GSK3B	S59	S63G	63	Missense	distal	4	no	6.913	3.670	EPSD	CCLE	6.007	Loss
CMGC_GSK_GSK3B_ST	P12036	NEFH	P49841	GSK3B	S61	S63G	63	Missense	proximal	2	no	6.829	6.570	EPSD	CCLE	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	P12036	NEFH	P49841	GSK3B	S546	A550T	550	Missense	distal	4	no	5.540	7.082	EPSD	CCLE	6.007	Gain
CMGC_GSK_GSK3B_ST	P12036	NEFH	P49841	GSK3B	S552	A550T	550	Missense	proximal	-2	no	7.707	8.069	EPSD	CCLE	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	P12036	NEFH	P49841	GSK3B	S620	E617K	617	Missense	distal	-3	no	6.904	6.914	EPSD	CCLE	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	P12036	NEFH	P49841	GSK3B	S702	S696Y	696	Missense	distal	-6	no	7.076	6.989	EPSD	CCLE	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	O00429	DNM1L	P49841	GSK3B	S544	S548P	548	Missense	distal	4	no	6.419	3.448	EPSD	CCLE	6.007	Loss
CMGC_GSK_GSK3B_ST	O00429	DNM1L	P49841	GSK3B	S548	S548P	548	Missense	central	0	yes	10.349	0.000	EPSD	CCLE	6.007	Loss
CMGC_GSK_GSK3B_ST	Q92908	GATA6	P49841	GSK3B	T515	P513H	513	Missense	proximal	-2	no	8.408	8.047	EPSD	CCLE	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	Q92908	GATA6	P49841	GSK3B	T515	T517I	517	Missense	proximal	2	no	8.408	8.343	EPSD	CCLE	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	Q92908	GATA6	P49841	GSK3B	S523	T517I	517	Missense	distal	-6	no	6.520	6.515	EPSD	CCLE	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	P17275	JUNB	P49841	GSK3B	S70	Y68C	68	Missense	proximal	-2	no	8.426	8.434	EPSD	CCLE	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	P17275	JUNB	P49841	GSK3B	T102	Y109H	109	Missense	distal	7	no	7.614	7.798	EPSD	CCLE	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	P17275	JUNB	P49841	GSK3B	S251	D253N	253	Missense	proximal	2	no	9.767	9.143	EPSD;PhosphoSitePlus	CCLE	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	P17275	JUNB	P49841	GSK3B	T255	D253N	253	Missense	proximal	-2	no	12.175	11.962	PhosphoSitePlus;EPSD	CCLE	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	P17275	JUNB	P49841	GSK3B	S259	D253N	253	Missense	distal	-6	no	8.319	8.341	EPSD	CCLE	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	P30304	CDC25A	P49841	GSK3B	S505	R506W	506	Missense	proximal	1	no	6.134	6.351	EPSD	CCLE	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	P30304	CDC25A	P49841	GSK3B	S505	L498P	498	Missense	distal	-7	no	6.134	6.132	EPSD	CCLE	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	Q9NRR4	DROSHA	P49841	GSK3B	T274	R277L	277	Missense	distal	3	no	8.231	8.301	EPSD	CCLE	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	Q9NRR4	DROSHA	P49841	GSK3B	S276	R277L	277	Missense	proximal	1	no	8.553	8.012	EPSD	CCLE	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	Q9NRR4	DROSHA	P49841	GSK3B	S284	R277L	277	Missense	distal	-7	no	6.751	6.733	EPSD	CCLE	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	Q9NRR4	DROSHA	P49841	GSK3B	S491	S494C	494	Missense	distal	3	no	7.852	7.637	EPSD	CCLE	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	Q9NRR4	DROSHA	P49841	GSK3B	T747	M740I	740	Missense	distal	-7	no	6.272	6.279	EPSD	CCLE	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	P15924	DSP	P49841	GSK3B	S2594	T2595I	2595	Missense	proximal	1	no	6.223	5.533	EPSD	CCLE	6.007	Loss
CMGC_GSK_GSK3B_ST	P15924	DSP	P49841	GSK3B	S2598	T2595I	2595	Missense	distal	-3	no	6.965	7.053	EPSD	CCLE	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	P15924	DSP	P49841	GSK3B	S2825	S2831A	2831	Missense	distal	6	no	9.505	9.504	EPSD	CCLE	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	P15924	DSP	P49841	GSK3B	S2827	S2831A	2831	Missense	distal	4	no	7.990	5.579	EPSD	CCLE	6.007	Loss
CMGC_GSK_GSK3B_ST	P15924	DSP	P49841	GSK3B	S2829	S2831A	2831	Missense	proximal	2	no	10.627	10.635	EPSD	CCLE	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	P15924	DSP	P49841	GSK3B	S2831	S2831A	2831	Missense	central	0	yes	7.617	0.000	EPSD	CCLE	6.007	Loss
CMGC_GSK_GSK3B_ST	P15924	DSP	P49841	GSK3B	S2833	S2831A	2831	Missense	proximal	-2	no	9.890	9.555	EPSD	CCLE	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	P15924	DSP	P49841	GSK3B	S2835	S2831A	2831	Missense	distal	-4	no	8.493	7.333	EPSD	CCLE	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	P15924	DSP	P49841	GSK3B	S2837	S2831A	2831	Missense	distal	-6	no	9.051	9.061	EPSD	CCLE	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	P15924	DSP	P49841	GSK3B	S2841	R2847K	2847	Missense	distal	6	no	9.923	9.922	EPSD	CCLE	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	P15924	DSP	P49841	GSK3B	S2845	R2847K	2847	Missense	proximal	2	no	9.477	9.411	PhosphoSitePlus;EPSD	CCLE	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	P15924	DSP	P49841	GSK3B	S2849	R2847K	2847	Missense	proximal	-2	no	6.665	6.646	EPSD;PhosphoSitePlus	CCLE	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	P15924	DSP	P49841	GSK3B	T2853	R2847K	2847	Missense	distal	-6	no	6.657	6.652	EPSD	CCLE	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	Q07812	BAX	P49841	GSK3B	S163	T167M	167	Missense	distal	4	no	9.392	8.026	PhosphoSitePlus	CCLE	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	P33076	CIITA	P49841	GSK3B	S280	R283W	283	Missense	distal	3	no	6.911	7.170	EPSD	CCLE	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	P33076	CIITA	P49841	GSK3B	S373	V366A	366	Missense	distal	-7	no	6.191	6.192	PhosphoSitePlus	CCLE	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	P33076	CIITA	P49841	GSK3B	S373	R369S	369	Missense	distal	-4	no	6.191	7.378	PhosphoSitePlus	CCLE	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	P33076	CIITA	P49841	GSK3B	S834	G831S	831	Missense	distal	-3	no	6.984	6.988	EPSD	CCLE	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	P33076	CIITA	P49841	GSK3B	S834	L833P	833	Missense	proximal	-1	no	6.984	7.115	EPSD	CCLE	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	P33076	CIITA	P49841	GSK3B	S943	S944L	944	Missense	proximal	1	no	5.113	6.097	EPSD	CCLE	6.007	Gain
CMGC_GSK_GSK3B_ST	P33076	CIITA	P49841	GSK3B	S944	S944L	944	Missense	central	0	yes	6.146	0.000	EPSD	CCLE	6.007	Loss
CMGC_GSK_GSK3B_ST	P33076	CIITA	P49841	GSK3B	S944	D946N	946	Missense	proximal	2	no	6.146	5.522	EPSD	CCLE	6.007	Loss
CMGC_GSK_GSK3B_ST	Q14103	HNRNPD	P49841	GSK3B	S190	D192V	192	Missense	proximal	2	no	6.370	6.009	EPSD	CCLE	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	P23246	SFPQ	P49841	GSK3B	T177	P179L	179	Missense	proximal	2	no	6.783	6.399	EPSD	CCLE	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	P23246	SFPQ	P49841	GSK3B	T226	G223A	223	Missense	distal	-3	no	8.733	8.758	EPSD	CCLE	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	P23246	SFPQ	P49841	GSK3B	S379	R376F	376	Missense	distal	-3	no	8.533	8.431	EPSD	CCLE	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	P23246	SFPQ	P49841	GSK3B	T687	M683T	683	Missense	distal	-4	no	7.106	7.831	PhosphoSitePlus	CCLE	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	Q96KS0	EGLN2	P49841	GSK3B	S130	P129H	129	Missense	proximal	-1	no	8.108	8.000	EPSD	CCLE	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	Q9UKA4	AKAP11	P49841	GSK3B	S288	N286S	286	Missense	proximal	-2	no	8.102	8.331	EPSD	CCLE	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	Q9UKA4	AKAP11	P49841	GSK3B	S483	Y488H	488	Missense	distal	5	no	6.479	6.805	EPSD	CCLE	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	Q9UKA4	AKAP11	P49841	GSK3B	S1483	G1479C	1479	Missense	distal	-4	no	6.866	5.180	EPSD	CCLE	6.007	Loss
CMGC_GSK_GSK3B_ST	Q9UKA4	AKAP11	P49841	GSK3B	S1483	G1479V	1479	Missense	distal	-4	no	6.866	6.061	EPSD	CCLE	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	P56524	HDAC4	P49841	GSK3B	S290	A291T	291	Missense	proximal	1	no	5.827	6.369	EPSD	CCLE	6.007	Gain
CMGC_GSK_GSK3B_ST	P56524	HDAC4	P49841	GSK3B	S294	A291T	291	Missense	distal	-3	no	8.269	8.273	EPSD	CCLE	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	P56524	HDAC4	P49841	GSK3B	S298	A291T	291	Missense	distal	-7	no	10.108	10.113	EPSD;PhosphoSitePlus	CCLE	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	P56524	HDAC4	P49841	GSK3B	S628	A635V	635	Missense	distal	7	no	8.322	8.400	EPSD	CCLE	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	P56524	HDAC4	P49841	GSK3B	S628	G622V	622	Missense	distal	-6	no	8.322	8.239	EPSD	CCLE	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	P56524	HDAC4	P49841	GSK3B	S633	A635V	635	Missense	proximal	2	no	8.220	7.943	EPSD	CCLE	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	Q92993	KAT5	P49841	GSK3B	S86	L83I	83	Missense	distal	-3	no	8.784	8.888	PhosphoSitePlus;EPSD	CCLE	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	Q92993	KAT5	P49841	GSK3B	S86	P88S	88	Missense	proximal	2	no	8.784	8.340	PhosphoSitePlus;EPSD	CCLE	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	Q92993	KAT5	P49841	GSK3B	S86	P88F	88	Missense	proximal	2	no	8.784	7.995	PhosphoSitePlus;EPSD	CCLE	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	Q92993	KAT5	P49841	GSK3B	S86	P88L	88	Missense	proximal	2	no	8.784	8.400	PhosphoSitePlus;EPSD	CCLE	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	Q92993	KAT5	P49841	GSK3B	S86	E92Q	92	Missense	distal	6	no	8.784	8.786	PhosphoSitePlus;EPSD	CCLE	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	Q92993	KAT5	P49841	GSK3B	S90	L83I	83	Missense	distal	-7	no	9.797	9.825	EPSD;PhosphoSitePlus	CCLE	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	Q92993	KAT5	P49841	GSK3B	S90	P88S	88	Missense	proximal	-2	no	9.797	9.541	EPSD;PhosphoSitePlus	CCLE	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	Q92993	KAT5	P49841	GSK3B	S90	P88F	88	Missense	proximal	-2	no	9.797	9.210	EPSD;PhosphoSitePlus	CCLE	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	Q92993	KAT5	P49841	GSK3B	S90	P88L	88	Missense	proximal	-2	no	9.797	9.467	EPSD;PhosphoSitePlus	CCLE	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	Q92993	KAT5	P49841	GSK3B	S90	E92Q	92	Missense	proximal	2	no	9.797	10.107	EPSD;PhosphoSitePlus	CCLE	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	Q92993	KAT5	P49841	GSK3B	S98	E92Q	92	Missense	distal	-6	no	5.973	6.031	EPSD	CCLE	6.007	Gain
CMGC_GSK_GSK3B_ST	P14618	PKM	P49841	GSK3B	S406	T412A	412	Missense	distal	6	no	6.023	6.019	EPSD	CCLE	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	Q96R06	SPAG5	P49841	GSK3B	S411	E416D	416	Missense	distal	5	no	6.282	6.079	EPSD	CCLE	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	Q96R06	SPAG5	P49841	GSK3B	S559	L560F	560	Missense	proximal	1	no	6.077	4.707	EPSD	CCLE	6.007	Loss
CMGC_GSK_GSK3B_ST	Q96R06	SPAG5	P49841	GSK3B	T1171	I1175S	1175	Missense	distal	4	no	3.919	7.241	EPSD	CCLE	6.007	Gain
CMGC_GSK_GSK3B_ST	O60341	KDM1A	P49841	GSK3B	T104	T104I	104	Missense	central	0	yes	6.853	0.000	EPSD	CCLE	6.007	Loss
CMGC_GSK_GSK3B_ST	O60341	KDM1A	P49841	GSK3B	S111	T104I	104	Missense	distal	-7	no	6.142	6.143	EPSD	CCLE	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	Q9Y2X9	ZNF281	P49841	GSK3B	S255	D248E	248	Missense	distal	-7	no	8.769	8.799	EPSD	CCLE	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	Q9Y2X9	ZNF281	P49841	GSK3B	S484	V490I	490	Missense	distal	6	no	6.141	6.150	EPSD	CCLE	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	Q9Y2X9	ZNF281	P49841	GSK3B	S484	P487S	487	Missense	distal	3	no	6.141	6.123	EPSD	CCLE	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	Q9Y2X9	ZNF281	P49841	GSK3B	S837	A834T	834	Missense	distal	-3	no	6.375	6.379	EPSD	CCLE	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	P38936	CDKN1A	P49841	GSK3B	S27	P24T	24	Missense	distal	-3	no	8.454	8.596	EPSD	CCLE	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	Q9BZS1	FOXP3	P49841	GSK3B	S19	S13P	13	Missense	distal	-6	no	9.591	9.612	EPSD	CCLE	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	Q9BZS1	FOXP3	P49841	GSK3B	S418	R417Q	417	Missense	proximal	-1	no	7.903	7.933	EPSD	CCLE	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	O43602	DCX	P49841	GSK3B	T289	A286V	286	Missense	distal	-3	no	7.657	7.804	EPSD	CCLE	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	O43602	DCX	P49841	GSK3B	S306	P307Q	307	Missense	proximal	1	no	8.211	4.943	EPSD	CCLE	6.007	Loss
CMGC_GSK_GSK3B_ST	P22670	RFX1	P49841	GSK3B	S60	T56A	56	Missense	distal	-4	no	6.271	5.446	EPSD	CCLE	6.007	Loss
CMGC_GSK_GSK3B_ST	P22670	RFX1	P49841	GSK3B	S120	S126N	126	Missense	distal	6	no	10.017	10.010	EPSD;PhosphoSitePlus	CCLE	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	P22670	RFX1	P49841	GSK3B	T124	S126N	126	Missense	proximal	2	no	6.700	6.168	PhosphoSitePlus;EPSD	CCLE	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	P08238	HSP90AB1	P49841	GSK3B	S63	D66E	66	Missense	distal	3	no	6.915	6.801	EPSD	CCLE	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	Q15797	SMAD1	P49841	GSK3B	T202	P207S	207	Missense	distal	5	no	9.463	8.509	PhosphoSitePlus	CCLE	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	Q15797	SMAD1	P49841	GSK3B	S206	P207S	207	Missense	proximal	1	no	10.197	6.352	EPSD	CCLE	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	Q15797	SMAD1	P49841	GSK3B	S214	P207S	207	Missense	distal	-7	no	8.465	8.467	EPSD	CCLE	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	Q15797	SMAD1	P49841	GSK3B	S214	S214I	214	Missense	central	0	yes	8.465	0.000	EPSD	CCLE	6.007	Loss
CMGC_GSK_GSK3B_ST	Q15797	SMAD1	P49841	GSK3B	S456	P460S	460	Missense	distal	4	no	7.866	10.837	EPSD	CCLE	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	Q07820	MCL1	P49841	GSK3B	T70	R74L	74	Missense	distal	4	no	6.124	6.444	EPSD	CCLE	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	Q07820	MCL1	P49841	GSK3B	T70	R74Q	74	Missense	distal	4	no	6.124	5.599	EPSD	CCLE	6.007	Loss
CMGC_GSK_GSK3B_ST	Q07820	MCL1	P49841	GSK3B	T70	S73P	73	Missense	distal	3	no	6.124	6.142	EPSD	CCLE	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	Q07820	MCL1	P49841	GSK3B	S150	T156R	156	Missense	distal	6	no	6.613	6.606	EPSD	CCLE	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	Q07820	MCL1	P49841	GSK3B	S155	T156R	156	Missense	proximal	1	no	6.717	7.588	EPSD	CCLE	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	Q07820	MCL1	P49841	GSK3B	S159	T156R	156	Missense	distal	-3	no	9.113	9.257	PhosphoSitePlus;EPSD	CCLE	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	Q07820	MCL1	P49841	GSK3B	T163	T156R	156	Missense	distal	-7	no	9.133	9.124	EPSD;PhosphoSitePlus	CCLE	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	Q9Y6K9	IKBKG	P49841	GSK3B	S31	E29K	29	Missense	proximal	-2	no	9.414	9.383	PhosphoSitePlus;EPSD	CCLE	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	Q96F46	IL17RA	P49841	GSK3B	S708	C703F	703	Missense	distal	-5	no	6.692	6.733	EPSD	CCLE	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	Q96F46	IL17RA	P49841	GSK3B	S708	P709L	709	Missense	proximal	1	no	6.692	3.832	EPSD	CCLE	6.007	Loss
CMGC_GSK_GSK3B_ST	Q96F46	IL17RA	P49841	GSK3B	S726	V721L	721	Missense	distal	-5	no	10.550	10.079	EPSD	CCLE	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	Q96F46	IL17RA	P49841	GSK3B	S726	S730N	730	Missense	distal	4	no	10.550	6.940	EPSD	CCLE	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	Q96F46	IL17RA	P49841	GSK3B	S731	S730N	730	Missense	proximal	-1	no	5.946	6.008	EPSD	CCLE	6.007	Gain
CMGC_GSK_GSK3B_ST	Q96F46	IL17RA	P49841	GSK3B	T732	S730N	730	Missense	proximal	-2	no	7.850	7.621	EPSD	CCLE	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	Q96F46	IL17RA	P49841	GSK3B	S736	S730N	730	Missense	distal	-6	no	6.973	6.971	EPSD	CCLE	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	Q96F46	IL17RA	P49841	GSK3B	S829	D832H	832	Missense	distal	3	no	7.197	7.074	EPSD	CCLE	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	Q13485	SMAD4	P49841	GSK3B	T269	T273I	273	Missense	distal	4	no	6.109	3.656	EPSD;PhosphoSitePlus	CCLE	6.007	Loss
CMGC_GSK_GSK3B_ST	Q13485	SMAD4	P49841	GSK3B	T273	T273I	273	Missense	central	0	yes	7.721	0.000	PhosphoSitePlus;EPSD	CCLE	6.007	Loss
CMGC_GSK_GSK3B_ST	Q13485	SMAD4	P49841	GSK3B	T277	T273I	273	Missense	distal	-4	no	7.392	5.244	EPSD	CCLE	6.007	Loss
CMGC_GSK_GSK3B_ST	P21796	VDAC1	P49841	GSK3B	S101	S102P	102	Missense	proximal	1	no	3.318	7.162	EPSD	CCLE	6.007	Gain
CMGC_GSK_GSK3B_ST	P21796	VDAC1	P49841	GSK3B	S104	S102P	102	Missense	proximal	-2	no	6.317	6.573	EPSD	CCLE	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	O60346	PHLPP1	P49841	GSK3B	S151	A145T	145	Missense	distal	-6	no	6.298	6.230	EPSD	CCLE	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	O60346	PHLPP1	P49841	GSK3B	S151	H150Q	150	Missense	proximal	-1	no	6.298	6.243	EPSD	CCLE	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	O60346	PHLPP1	P49841	GSK3B	S412	T409M	409	Missense	distal	-3	no	6.136	6.082	EPSD	CCLE	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	O60346	PHLPP1	P49841	GSK3B	S412	P413S	413	Missense	proximal	1	no	6.136	2.291	EPSD	CCLE	6.007	Loss
CMGC_GSK_GSK3B_ST	O60346	PHLPP1	P49841	GSK3B	T1363	I1370V	1370	Missense	distal	7	no	9.412	9.502	EPSD;PhosphoSitePlus	CCLE	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	O43623	SNAI2	P49841	GSK3B	S87	D93G	93	Missense	distal	6	no	6.504	6.508	EPSD	CCLE	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	O43623	SNAI2	P49841	GSK3B	S92	D93G	93	Missense	proximal	1	no	7.260	7.169	EPSD;PhosphoSitePlus	CCLE	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	O43623	SNAI2	P49841	GSK3B	S96	D93G	93	Missense	distal	-3	no	7.461	7.411	EPSD;PhosphoSitePlus	CCLE	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	O43623	SNAI2	P49841	GSK3B	S100	D93G	93	Missense	distal	-7	no	7.492	7.487	EPSD;PhosphoSitePlus	CCLE	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	P07900	HSP90AA1	P49841	GSK3B	T704	A710V	710	Missense	distal	6	no	6.072	6.063	EPSD	CCLE	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	P07900	HSP90AA1	P49841	GSK3B	T704	A705V	705	Missense	proximal	1	no	6.072	6.813	EPSD	CCLE	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	P07900	HSP90AA1	P49841	GSK3B	S709	A710V	710	Missense	proximal	1	no	5.834	6.575	EPSD	CCLE	6.007	Gain
CMGC_GSK_GSK3B_ST	Q9BXF6	RAB11FIP5	P49841	GSK3B	T250	S254L	254	Missense	distal	4	no	6.575	3.858	EPSD	CCLE	6.007	Loss
CMGC_GSK_GSK3B_ST	Q9BXF6	RAB11FIP5	P49841	GSK3B	S256	S254L	254	Missense	proximal	-2	no	6.295	6.221	EPSD	CCLE	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	Q9BXF6	RAB11FIP5	P49841	GSK3B	S260	S254L	254	Missense	distal	-6	no	7.907	7.906	EPSD	CCLE	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	Q9BXF6	RAB11FIP5	P49841	GSK3B	T276	S282N	282	Missense	distal	6	no	6.143	6.137	PhosphoSitePlus;EPSD	CCLE	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	Q9BXF6	RAB11FIP5	P49841	GSK3B	S278	S282N	282	Missense	distal	4	no	8.421	4.811	EPSD	CCLE	6.007	Loss
CMGC_GSK_GSK3B_ST	Q9BXF6	RAB11FIP5	P49841	GSK3B	S282	S282N	282	Missense	central	0	yes	6.182	0.000	EPSD	CCLE	6.007	Loss
CMGC_GSK_GSK3B_ST	Q9BXF6	RAB11FIP5	P49841	GSK3B	S283	S282N	282	Missense	proximal	-1	no	6.743	6.805	EPSD	CCLE	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	Q9BXF6	RAB11FIP5	P49841	GSK3B	S296	K303R	303	Missense	distal	7	no	5.511	6.018	EPSD	CCLE	6.007	Gain
CMGC_GSK_GSK3B_ST	Q9BXF6	RAB11FIP5	P49841	GSK3B	T305	K303R	303	Missense	proximal	-2	no	5.990	6.008	EPSD	CCLE	6.007	Gain
CMGC_GSK_GSK3B_ST	Q9BXF6	RAB11FIP5	P49841	GSK3B	S473	H468Y	468	Missense	distal	-5	no	5.932	6.417	EPSD	CCLE	6.007	Gain
CMGC_GSK_GSK3B_ST	Q9BXF6	RAB11FIP5	P49841	GSK3B	S494	I490V	490	Missense	distal	-4	no	6.041	7.290	EPSD	CCLE	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	Q9BXF6	RAB11FIP5	P49841	GSK3B	S523	V527L	527	Missense	distal	4	no	6.242	5.914	EPSD	CCLE	6.007	Loss
CMGC_GSK_GSK3B_ST	P08047	SP1	P49841	GSK3B	S40	G44S	44	Missense	distal	4	no	3.319	6.562	EPSD	CCLE	6.007	Gain
CMGC_GSK_GSK3B_ST	P08047	SP1	P49841	GSK3B	S41	G44S	44	Missense	distal	3	no	6.267	6.223	EPSD	CCLE	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	P08047	SP1	P49841	GSK3B	S42	G44S	44	Missense	proximal	2	no	6.374	6.632	EPSD	CCLE	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	P08047	SP1	P49841	GSK3B	T43	G44S	44	Missense	proximal	1	no	6.239	5.588	EPSD	CCLE	6.007	Loss
CMGC_GSK_GSK3B_ST	P08047	SP1	P49841	GSK3B	S698	R694C	694	Missense	distal	-4	no	6.831	5.904	EPSD	CCLE	6.007	Loss
CMGC_GSK_GSK3B_ST	P31749	AKT1	P49841	GSK3B	T435	D439H	439	Missense	distal	4	no	6.225	4.892	EPSD	CCLE	6.007	Loss
CMGC_GSK_GSK3B_ST	P04637	TP53	P49841	GSK3B	S33	E28Q	28	Missense	distal	-5	no	10.252	9.964	EPSD	CCLE	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	Q14896	MYBPC3	P49841	GSK3B	T607	A609P	609	Missense	proximal	2	no	7.615	8.051	EPSD	CCLE	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	Q14896	MYBPC3	P49841	GSK3B	S1067	R1073Q	1073	Missense	distal	6	no	9.012	9.013	EPSD	CCLE	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	Q01094	E2F1	P49841	GSK3B	S307	G309R	309	Missense	proximal	2	no	8.116	8.393	EPSD	CCLE	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	Q01094	E2F1	P49841	GSK3B	T311	G309R	309	Missense	proximal	-2	no	7.138	7.140	EPSD	CCLE	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	Q01094	E2F1	P49841	GSK3B	S313	G309R	309	Missense	distal	-4	no	6.819	6.061	EPSD	CCLE	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	Q01094	E2F1	P49841	GSK3B	S375	R373S	373	Missense	proximal	-2	no	6.762	6.878	EPSD	CCLE	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	Q01094	E2F1	P49841	GSK3B	S403	L402F	402	Missense	proximal	-1	no	9.524	9.468	EPSD;PhosphoSitePlus	CCLE	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	Q15746	MYLK	P49841	GSK3B	S18	D20G	20	Missense	proximal	2	no	8.033	7.683	EPSD	CCLE	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	Q15746	MYLK	P49841	GSK3B	S391	D393H	393	Missense	proximal	2	no	6.467	6.050	EPSD	CCLE	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	Q15746	MYLK	P49841	GSK3B	T1230	K1224M	1224	Missense	distal	-6	no	7.083	7.093	EPSD	CCLE	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	P20393	NR1D1	P49841	GSK3B	S84	G79S	79	Missense	distal	-5	no	7.876	7.410	EPSD	CCLE	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	P20393	NR1D1	P49841	GSK3B	S84	D77N	77	Missense	distal	-7	no	7.876	7.880	EPSD	CCLE	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	P20393	NR1D1	P49841	GSK3B	S86	G79S	79	Missense	distal	-7	no	6.187	6.189	EPSD	CCLE	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	Q9UKT5	FBXO4	P49841	GSK3B	S8	S4G	4	Missense	distal	-4	no	7.416	6.988	EPSD	CCLE	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	Q9NYF8	BCLAF1	P49841	GSK3B	S6	H9Y	9	Missense	distal	3	no	7.649	7.256	EPSD	CCLE	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	Q9NYF8	BCLAF1	P49841	GSK3B	S6	R3P	3	Missense	distal	-3	no	7.649	7.364	EPSD	CCLE	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	Q9NYF8	BCLAF1	P49841	GSK3B	S15	H9Y	9	Missense	distal	-6	no	7.933	7.881	EPSD	CCLE	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	Q9NYF8	BCLAF1	P49841	GSK3B	S19	S25P	25	Missense	distal	6	no	7.212	7.214	EPSD	CCLE	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	Q9NYF8	BCLAF1	P49841	GSK3B	S104	H101Q	101	Missense	distal	-3	no	7.978	7.896	EPSD	CCLE	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	Q9NYF8	BCLAF1	P49841	GSK3B	S114	R113I	113	Missense	proximal	-1	no	7.790	7.777	EPSD	CCLE	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	Q9NYF8	BCLAF1	P49841	GSK3B	S222	P229R	229	Missense	distal	7	no	6.497	6.998	EPSD	CCLE	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	Q9NYF8	BCLAF1	P49841	GSK3B	S225	P229R	229	Missense	distal	4	no	6.242	6.175	EPSD	CCLE	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	Q9NYF8	BCLAF1	P49841	GSK3B	S228	P229R	229	Missense	proximal	1	no	7.154	4.834	EPSD	CCLE	6.007	Loss
CMGC_GSK_GSK3B_ST	Q9NYF8	BCLAF1	P49841	GSK3B	S230	P229R	229	Missense	proximal	-1	no	8.932	8.739	EPSD	CCLE	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	Q9NYF8	BCLAF1	P49841	GSK3B	T234	P229R	229	Missense	distal	-5	no	5.358	6.212	EPSD	CCLE	6.007	Gain
CMGC_GSK_GSK3B_ST	Q9NYF8	BCLAF1	P49841	GSK3B	S249	M247I	247	Missense	proximal	-2	no	7.274	7.595	EPSD	CCLE	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	Q9NYF8	BCLAF1	P49841	GSK3B	S253	M247I	247	Missense	distal	-6	no	7.196	7.186	EPSD	CCLE	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	Q9NYF8	BCLAF1	P49841	GSK3B	S315	R316I	316	Missense	proximal	1	no	8.876	7.314	EPSD	CCLE	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	Q9NYF8	BCLAF1	P49841	GSK3B	S385	G390A	390	Missense	distal	5	no	6.855	6.737	EPSD	CCLE	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	Q9NYF8	BCLAF1	P49841	GSK3B	S496	K492T	492	Missense	distal	-4	no	5.876	6.406	EPSD	CCLE	6.007	Gain
CMGC_GSK_GSK3B_ST	Q9NYF8	BCLAF1	P49841	GSK3B	T644	P649L	649	Missense	distal	5	no	9.401	8.121	EPSD	CCLE	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	Q9NYF8	BCLAF1	P49841	GSK3B	S658	S660R	660	Missense	proximal	2	no	8.786	8.804	EPSD	CCLE	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	Q9NYF8	BCLAF1	P49841	GSK3B	S714	R708W	708	Missense	distal	-6	no	8.636	8.663	EPSD	CCLE	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	Q9NYF8	BCLAF1	P49841	GSK3B	S749	S752A	752	Missense	distal	3	no	7.933	7.596	EPSD	CCLE	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	Q9NYF8	BCLAF1	P49841	GSK3B	S751	S752A	752	Missense	proximal	1	no	7.694	7.807	EPSD	CCLE	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	Q9NYF8	BCLAF1	P49841	GSK3B	S755	S752A	752	Missense	distal	-3	no	7.502	7.523	EPSD	CCLE	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	Q9NYF8	BCLAF1	P49841	GSK3B	S757	S752A	752	Missense	distal	-5	no	8.512	8.790	EPSD	CCLE	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	Q9NYF8	BCLAF1	P49841	GSK3B	S759	S752A	752	Missense	distal	-7	no	7.745	7.768	EPSD	CCLE	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	O75030	MITF	P49841	GSK3B	S176	G174R	174	Missense	proximal	-2	no	6.901	6.903	EPSD	CCLE	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	O75030	MITF	P49841	GSK3B	S180	G174R	174	Missense	distal	-6	no	8.658	8.585	EPSD	CCLE	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	O75030	MITF	P49841	GSK3B	S491	S491F	491	Missense	central	0	yes	6.724	0.000	EPSD	CCLE	6.007	Loss
CMGC_GSK_GSK3B_ST	O75030	MITF	P49841	GSK3B	S508	S512N	512	Missense	distal	4	no	7.924	4.314	EPSD	CCLE	6.007	Loss
CMGC_GSK_GSK3B_ST	O75030	MITF	P49841	GSK3B	S511	S512N	512	Missense	proximal	1	no	6.054	4.379	EPSD	CCLE	6.007	Loss
CMGC_GSK_GSK3B_ST	O75030	MITF	P49841	GSK3B	S512	S512N	512	Missense	central	0	yes	9.465	0.000	EPSD	CCLE	6.007	Loss
CMGC_GSK_GSK3B_ST	O75030	MITF	P49841	GSK3B	S518	S512N	512	Missense	distal	-6	no	6.269	6.266	EPSD	CCLE	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	P48436	SOX9	P49841	GSK3B	S33	G40C	40	Missense	distal	7	no	8.960	9.332	EPSD	CCLE	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	P48436	SOX9	P49841	GSK3B	S37	G40C	40	Missense	distal	3	no	8.222	7.963	EPSD	CCLE	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	P48436	SOX9	P49841	GSK3B	S494	Q496H	496	Missense	proximal	2	no	7.457	6.909	EPSD	CCLE	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	P06401	PGR	P49841	GSK3B	S25	C29Y	29	Missense	distal	4	no	3.875	6.495	EPSD	CCLE	6.007	Gain
CMGC_GSK_GSK3B_ST	P06401	PGR	P49841	GSK3B	S273	V268F	268	Missense	distal	-5	no	6.161	6.141	EPSD	CCLE	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	P06401	PGR	P49841	GSK3B	S345	A348G	348	Missense	distal	3	no	9.402	9.783	EPSD	CCLE	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	P06401	PGR	P49841	GSK3B	T351	A348G	348	Missense	distal	-3	no	7.159	7.134	EPSD	CCLE	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	O75952	CABYR	P49841	GSK3B	T75	K78E	78	Missense	distal	3	no	7.069	7.176	EPSD	CCLE	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	O75952	CABYR	P49841	GSK3B	S116	R112K	112	Missense	distal	-4	no	5.777	6.099	EPSD	CCLE	6.007	Gain
CMGC_GSK_GSK3B_ST	Q01518	CAP1	P49841	GSK3B	S255	A259T	259	Missense	distal	4	no	4.799	6.341	EPSD	CCLE	6.007	Gain
CMGC_GSK_GSK3B_ST	P04150	NR3C1	P49841	GSK3B	S79	K80N	80	Missense	proximal	1	no	6.608	4.635	EPSD	CCLE	6.007	Loss
CMGC_GSK_GSK3B_ST	P04150	NR3C1	P49841	GSK3B	S141	A146F	146	Missense	distal	5	no	6.393	5.801	EPSD	CCLE	6.007	Loss
CMGC_GSK_GSK3B_ST	P04150	NR3C1	P49841	GSK3B	S395	S394L	394	Missense	proximal	-1	no	7.593	7.518	EPSD	CCLE	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	P04150	NR3C1	P49841	GSK3B	S395	G392D	392	Missense	distal	-3	no	7.593	7.643	EPSD	CCLE	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	Q00613	HSF1	P49841	GSK3B	S237	P243L	243	Missense	distal	6	no	6.380	6.373	EPSD	CCLE	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	Q00613	HSF1	P49841	GSK3B	S244	P243L	243	Missense	proximal	-1	no	9.276	9.145	EPSD	CCLE	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	Q00613	HSF1	P49841	GSK3B	S283	R287M	287	Missense	distal	4	no	5.391	6.194	EPSD	CCLE	6.007	Gain
CMGC_GSK_GSK3B_ST	Q00613	HSF1	P49841	GSK3B	S292	R287M	287	Missense	distal	-5	no	7.295	6.899	EPSD	CCLE	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	Q00613	HSF1	P49841	GSK3B	S419	V424M	424	Missense	distal	5	no	7.800	8.162	EPSD	CCLE	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	Q9HB09	BCL2L12	P49841	GSK3B	S273	L277M	277	Missense	distal	4	no	8.561	9.044	EPSD	CCLE	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	O75581	LRP6	P49841	GSK3B	S1431	L1432M	1432	Missense	proximal	1	no	7.572	6.846	EPSD	CCLE	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	O75581	LRP6	P49841	GSK3B	S1435	L1432M	1432	Missense	distal	-3	no	8.170	8.132	EPSD	CCLE	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	O75581	LRP6	P49841	GSK3B	S1444	S1450T	1450	Missense	distal	6	no	6.997	6.999	EPSD	CCLE	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	Q9H0B6	KLC2	P49841	GSK3B	T450	T451S	451	Missense	proximal	1	no	6.253	5.599	EPSD	CCLE	6.007	Loss
CMGC_GSK_GSK3B_ST	Q9H0B6	KLC2	P49841	GSK3B	S611	S618N	618	Missense	distal	7	no	6.365	6.488	EPSD	CCLE	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	Q9H0B6	KLC2	P49841	GSK3B	S615	S618N	618	Missense	distal	3	no	9.158	9.206	EPSD	CCLE	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	Q6U7Q0	ZNF322	P49841	GSK3B	T79	V81F	81	Missense	proximal	2	no	6.537	6.461	EPSD	CCLE	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	Q6U7Q0	ZNF322	P49841	GSK3B	S391	A395T	395	Missense	distal	4	no	10.846	12.389	PhosphoSitePlus	CCLE	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	Q6R327	RICTOR	P49841	GSK3B	S221	C218Y	218	Missense	distal	-3	no	7.476	7.513	EPSD	CCLE	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	Q6R327	RICTOR	P49841	GSK3B	S1026	S1020I	1020	Missense	distal	-6	no	6.716	6.654	EPSD	CCLE	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	Q6R327	RICTOR	P49841	GSK3B	S1026	P1019Q	1019	Missense	distal	-7	no	6.716	6.733	EPSD	CCLE	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	Q6R327	RICTOR	P49841	GSK3B	S1122	K1119E	1119	Missense	distal	-3	no	6.052	6.042	EPSD	CCLE	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	Q6R327	RICTOR	P49841	GSK3B	T1361	T1365I	1365	Missense	distal	4	no	6.612	4.159	EPSD	CCLE	6.007	Loss
CMGC_GSK_GSK3B_ST	Q6R327	RICTOR	P49841	GSK3B	S1581	S1587G	1587	Missense	distal	6	no	7.230	7.227	EPSD	CCLE	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	Q6R327	RICTOR	P49841	GSK3B	S1585	S1587G	1587	Missense	proximal	2	no	6.811	6.552	EPSD	CCLE	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	Q6R327	RICTOR	P49841	GSK3B	S1587	S1587G	1587	Missense	central	0	yes	6.424	0.000	EPSD	CCLE	6.007	Loss
CMGC_GSK_GSK3B_ST	Q6R327	RICTOR	P49841	GSK3B	S1588	S1587G	1587	Missense	proximal	-1	no	7.334	7.341	EPSD	CCLE	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	P01106	MYC	P49841	GSK3B	T58	E54K	54	Missense	distal	-4	no	12.188	11.921	EPSD;PhosphoSitePlus	CCLE	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	P01106	MYC	P49841	GSK3B	T58	P57H	57	Missense	proximal	-1	no	12.188	12.081	EPSD;PhosphoSitePlus	CCLE	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	P01106	MYC	P49841	GSK3B	S62	P57H	57	Missense	distal	-5	no	6.697	7.021	PhosphoSitePlus;EPSD	CCLE	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	P01106	MYC	P49841	GSK3B	S62	L69I	69	Missense	distal	7	no	6.697	7.047	PhosphoSitePlus;EPSD	CCLE	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	P01106	MYC	P49841	GSK3B	S67	L69I	69	Missense	proximal	2	no	7.689	7.690	EPSD	CCLE	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	P01106	MYC	P49841	GSK3B	S67	Y74S	74	Missense	distal	7	no	7.689	7.247	EPSD	CCLE	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	P01106	MYC	P49841	GSK3B	S71	L69I	69	Missense	proximal	-2	no	8.090	8.153	EPSD	CCLE	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	P01106	MYC	P49841	GSK3B	S71	Y74S	74	Missense	distal	3	no	8.090	8.512	EPSD	CCLE	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	P01106	MYC	P49841	GSK3B	S71	T78R	78	Missense	distal	7	no	8.090	8.587	EPSD	CCLE	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	P01106	MYC	P49841	GSK3B	T78	Y74S	74	Missense	distal	-4	no	5.606	6.406	EPSD	CCLE	6.007	Gain
CMGC_GSK_GSK3B_ST	P01106	MYC	P49841	GSK3B	S202	K206T	206	Missense	distal	4	no	4.761	7.094	EPSD	CCLE	6.007	Gain
CMGC_GSK_GSK3B_ST	P35612	ADD2	P49841	GSK3B	S60	L67V	67	Missense	distal	7	no	6.927	7.366	EPSD	CCLE	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	P35612	ADD2	P49841	GSK3B	S528	A521G	521	Missense	distal	-7	no	7.100	7.075	EPSD	CCLE	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	P35612	ADD2	P49841	GSK3B	S613	S613R	613	Missense	central	0	yes	10.662	0.000	PhosphoSitePlus;EPSD	CCLE	6.007	Loss
CMGC_GSK_GSK3B_ST	P35612	ADD2	P49841	GSK3B	S617	S613R	613	Missense	distal	-4	no	9.420	8.234	EPSD	CCLE	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	P35612	ADD2	P49841	GSK3B	S689	G690A	690	Missense	proximal	1	no	8.096	7.558	EPSD	CCLE	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	P35612	ADD2	P49841	GSK3B	S693	G690A	690	Missense	distal	-3	no	12.171	12.196	EPSD;PhosphoSitePlus	CCLE	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	P35612	ADD2	P49841	GSK3B	S697	G690A	690	Missense	distal	-7	no	10.178	10.203	EPSD	CCLE	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	P25054	APC	P49841	GSK3B	S1038	S1044L	1044	Missense	distal	6	no	7.492	7.487	EPSD	CCLE	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	P25054	APC	P49841	GSK3B	S1664	T1661K	1661	Missense	distal	-3	no	8.205	8.204	EPSD	CCLE	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	P25054	APC	P49841	GSK3B	S1737	H1738P	1738	Missense	proximal	1	no	3.201	6.901	EPSD	CCLE	6.007	Gain
CMGC_GSK_GSK3B_ST	P25054	APC	P49841	GSK3B	S2022	E2015G	2015	Missense	distal	-7	no	6.546	6.511	EPSD	CCLE	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	P25054	APC	P49841	GSK3B	T2255	S2260N	2260	Missense	distal	5	no	6.155	5.834	EPSD	CCLE	6.007	Loss
CMGC_GSK_GSK3B_ST	P25054	APC	P49841	GSK3B	S2258	S2260N	2260	Missense	proximal	2	no	7.079	6.547	EPSD	CCLE	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	P25054	APC	P49841	GSK3B	S2260	S2260N	2260	Missense	central	0	yes	6.088	0.000	EPSD	CCLE	6.007	Loss
CMGC_GSK_GSK3B_ST	P25054	APC	P49841	GSK3B	T2348	L2345I	2345	Missense	distal	-3	no	6.595	6.699	EPSD	CCLE	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	P25054	APC	P49841	GSK3B	S2350	L2345I	2345	Missense	distal	-5	no	7.290	7.653	EPSD	CCLE	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	P25054	APC	P49841	GSK3B	S2621	F2620C	2620	Missense	proximal	-1	no	9.358	9.453	EPSD	CCLE	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	P25054	APC	P49841	GSK3B	S2625	F2620C	2620	Missense	distal	-5	no	6.567	6.526	EPSD	CCLE	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	P25054	APC	P49841	GSK3B	S2627	F2620C	2620	Missense	distal	-7	no	7.373	7.386	EPSD	CCLE	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	P25054	APC	P49841	GSK3B	T2760	I2756V	2756	Missense	distal	-4	no	5.679	6.928	EPSD	CCLE	6.007	Gain
CMGC_GSK_GSK3B_ST	P25054	APC	P49841	GSK3B	S2763	I2756V	2756	Missense	distal	-7	no	6.296	6.290	EPSD	CCLE	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	P25054	APC	P49841	GSK3B	S2763	S2768R	2768	Missense	distal	5	no	6.296	6.613	EPSD	CCLE	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	P25054	APC	P49841	GSK3B	S2767	S2768R	2768	Missense	proximal	1	no	8.352	9.877	EPSD	CCLE	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	P25054	APC	P49841	GSK3B	S2768	S2768R	2768	Missense	central	0	yes	7.195	0.000	EPSD	CCLE	6.007	Loss
CMGC_GSK_GSK3B_ST	P25054	APC	P49841	GSK3B	S2772	S2768R	2768	Missense	distal	-4	no	9.633	8.447	EPSD	CCLE	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	Q99626	CDX2	P49841	GSK3B	S12	D10G	10	Missense	proximal	-2	no	6.474	6.372	EPSD	CCLE	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	Q99626	CDX2	P49841	GSK3B	S17	D10G	10	Missense	distal	-7	no	6.253	6.248	EPSD	CCLE	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	P30291	WEE1	P49841	GSK3B	S67	P64S	64	Missense	distal	-3	no	7.098	7.215	EPSD	CCLE	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	P30291	WEE1	P49841	GSK3B	S150	D148N	148	Missense	proximal	-2	no	6.239	6.025	EPSD	CCLE	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	Q14195	DPYSL3	P49841	GSK3B	S308	D315N	315	Missense	distal	7	no	8.188	8.256	EPSD	CCLE	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	Q15910	EZH2	P49841	GSK3B	S76	L71M	71	Missense	distal	-5	no	7.147	7.340	EPSD	CCLE	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	Q9Y6H5	SNCAIP	P49841	GSK3B	S80	V79F	79	Missense	proximal	-1	no	6.090	5.911	EPSD	CCLE	6.007	Loss
CMGC_GSK_GSK3B_ST	Q02156	PRKCE	P49841	GSK3B	S329	E328Q	328	Missense	proximal	-1	no	7.855	7.760	EPSD	CCLE	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	Q02156	PRKCE	P49841	GSK3B	S350	I356L	356	Missense	distal	6	no	7.705	7.701	EPSD	CCLE	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	P10914	IRF1	P49841	GSK3B	T311	L315F	315	Missense	distal	4	no	6.650	5.754	EPSD	CCLE	6.007	Loss
CMGC_GSK_GSK3B_ST	P40337	VHL	P49841	GSK3B	S38	S33L	33	Missense	distal	-5	no	6.340	6.449	EPSD	CCLE	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	P40337	VHL	P49841	GSK3B	S68	E70D	70	Missense	proximal	2	no	7.731	7.910	PhosphoSitePlus	CCLE	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	Q01201	RELB	P49841	GSK3B	S8	P10T	10	Missense	proximal	2	no	6.731	6.413	EPSD	CCLE	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	Q01201	RELB	P49841	GSK3B	T14	P10T	10	Missense	distal	-4	no	5.947	6.175	EPSD	CCLE	6.007	Gain
CMGC_GSK_GSK3B_ST	Q01201	RELB	P49841	GSK3B	S37	P30R	30	Missense	distal	-7	no	10.416	10.436	EPSD	CCLE	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	Q01201	RELB	P49841	GSK3B	S116	G112A	112	Missense	distal	-4	no	7.970	7.238	EPSD	CCLE	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	Q01201	RELB	P49841	GSK3B	S472	L473P	473	Missense	proximal	1	no	5.728	8.588	EPSD	CCLE	6.007	Gain
CMGC_GSK_GSK3B_ST	Q04206	RELA	P49841	GSK3B	S468	A467V	467	Missense	proximal	-1	no	8.201	8.404	PhosphoSitePlus	CCLE	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	Q04206	RELA	P49841	GSK3B	T505	L503P	503	Missense	proximal	-2	no	6.176	6.506	EPSD	CCLE	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	P17676	CEBPB	P49841	GSK3B	S231	P236L	236	Missense	distal	5	no	12.128	10.847	EPSD	CCLE	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	P17676	CEBPB	P49841	GSK3B	S231	P238L	238	Missense	distal	7	no	12.128	12.177	EPSD	CCLE	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	P17676	CEBPB	P49841	GSK3B	T235	P236L	236	Missense	proximal	1	no	7.921	5.061	EPSD	CCLE	6.007	Loss
CMGC_GSK_GSK3B_ST	P17676	CEBPB	P49841	GSK3B	T235	P238L	238	Missense	distal	3	no	7.921	7.603	EPSD	CCLE	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	P17676	CEBPB	P49841	GSK3B	S237	P236L	236	Missense	proximal	-1	no	6.521	6.389	EPSD	CCLE	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	P17676	CEBPB	P49841	GSK3B	S237	P238L	238	Missense	proximal	1	no	6.521	3.660	EPSD	CCLE	6.007	Loss
CMGC_GSK_GSK3B_ST	Q08050	FOXM1	P49841	GSK3B	S489	S493Y	493	Missense	distal	4	no	9.825	6.312	EPSD	CCLE	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	Q08050	FOXM1	P49841	GSK3B	T510	K514N	514	Missense	distal	4	no	7.126	6.718	EPSD	CCLE	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	Q08050	FOXM1	P49841	GSK3B	S518	K514N	514	Missense	distal	-4	no	7.087	6.654	EPSD	CCLE	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	Q08050	FOXM1	P49841	GSK3B	T524	M530I	530	Missense	distal	6	no	7.221	7.226	EPSD	CCLE	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	P41236	PPP1R2	P49841	GSK3B	S24	S20Y	20	Missense	distal	-4	no	6.267	5.467	EPSD	CCLE	6.007	Loss
CMGC_GSK_GSK3B_ST	P41236	PPP1R2	P49841	GSK3B	T73	M79T	79	Missense	distal	6	no	9.410	9.417	PhosphoSitePlus	CCLE	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	P41236	PPP1R2	P49841	GSK3B	T73	M78I	78	Missense	distal	5	no	9.410	8.882	PhosphoSitePlus	CCLE	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	P41236	PPP1R2	P49841	GSK3B	T177	E173Q	173	Missense	distal	-4	no	6.008	5.776	EPSD	CCLE	6.007	Loss
CMGC_GSK_GSK3B_ST	P13807	GYS1	P49841	GSK3B	S641	R635C	635	Missense	distal	-6	no	12.074	12.120	EPSD	CCLE	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	P49716	CEBPD	P49841	GSK3B	S167	R165H	165	Missense	proximal	-2	no	9.108	9.118	PhosphoSitePlus	CCLE	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	P49716	CEBPD	P49841	GSK3B	T171	R165H	165	Missense	distal	-6	no	6.438	6.461	EPSD	CCLE	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	P13051	UNG	P49841	GSK3B	S12	F10L	10	Missense	proximal	-2	no	7.468	7.725	EPSD	CCLE	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	P13051	UNG	P49841	GSK3B	S14	F10L	10	Missense	distal	-4	no	7.637	7.440	EPSD	CCLE	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	Q14494	NFE2L1	P49841	GSK3B	S112	S112F	112	Missense	central	0	yes	7.059	0.000	EPSD	CCLE	6.007	Loss
CMGC_GSK_GSK3B_ST	Q14494	NFE2L1	P49841	GSK3B	S116	S112F	112	Missense	distal	-4	no	8.993	7.839	EPSD	CCLE	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	O00327	ARNTL	P49841	GSK3B	S515	S520R	520	Missense	distal	5	no	7.085	7.402	EPSD	CCLE	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	O00327	ARNTL	P49841	GSK3B	S516	S520R	520	Missense	distal	4	no	7.707	4.670	EPSD	CCLE	6.007	Loss
CMGC_GSK_GSK3B_ST	O00327	ARNTL	P49841	GSK3B	S520	S520R	520	Missense	central	0	yes	6.514	0.000	EPSD	CCLE	6.007	Loss
CMGC_GSK_GSK3B_ST	O00327	ARNTL	P49841	GSK3B	T527	S520R	520	Missense	distal	-7	no	8.139	8.157	EPSD	CCLE	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	O00327	ARNTL	P49841	GSK3B	T527	P529R	529	Missense	proximal	2	no	8.139	7.714	EPSD	CCLE	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	O00327	ARNTL	P49841	GSK3B	S534	P529R	529	Missense	distal	-5	no	5.314	6.168	EPSD	CCLE	6.007	Gain
CMGC_GSK_GSK3B_ST	O00327	ARNTL	P49841	GSK3B	S592	S592N	592	Missense	central	0	yes	6.736	0.000	EPSD	CCLE	6.007	Loss
CMGC_GSK_GSK3B_ST	Q13887	KLF5	P49841	GSK3B	S303	G310E	310	Missense	distal	7	no	12.612	12.632	PhosphoSitePlus	CCLE	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	Q13887	KLF5	P49841	GSK3B	T323	L319P	319	Missense	distal	-4	no	7.049	7.835	EPSD	CCLE	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	O15516	CLOCK	P49841	GSK3B	S836	S841T	841	Missense	distal	5	no	6.348	6.326	EPSD	CCLE	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	P30281	CCND3	P49841	GSK3B	S259	S259F	259	Missense	central	0	yes	7.159	0.000	EPSD	CCLE	6.007	Loss
CMGC_GSK_GSK3B_ST	P30281	CCND3	P49841	GSK3B	S264	S259F	259	Missense	distal	-5	no	6.434	6.994	EPSD	CCLE	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	O15033	AREL1	P49841	GSK3B	S358	K365N	365	Missense	distal	7	no	7.688	7.881	EPSD	CCLE	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	P04198	MYCN	P49841	GSK3B	T142	R138S	138	Missense	distal	-4	no	5.696	6.883	EPSD	CCLE	6.007	Gain
CMGC_GSK_GSK3B_ST	P04198	MYCN	P49841	GSK3B	S145	R138S	138	Missense	distal	-7	no	7.823	7.805	EPSD	CCLE	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	P04198	MYCN	P49841	GSK3B	S375	D379E	379	Missense	distal	4	no	5.954	6.357	EPSD	CCLE	6.007	Gain
CMGC_GSK_GSK3B_ST	P54132	BLM	P49841	GSK3B	S42	N46S	46	Missense	distal	4	no	2.552	6.162	EPSD	CCLE	6.007	Gain
CMGC_GSK_GSK3B_ST	P54132	BLM	P49841	GSK3B	S304	I309F	309	Missense	distal	5	no	7.653	7.652	EPSD	CCLE	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	P54132	BLM	P49841	GSK3B	S312	I309F	309	Missense	distal	-3	no	6.066	6.020	EPSD	CCLE	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	P54132	BLM	P49841	GSK3B	S316	I309F	309	Missense	distal	-7	no	6.978	6.960	EPSD	CCLE	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	P54132	BLM	P49841	GSK3B	S422	D420E	420	Missense	proximal	-2	no	6.516	6.428	EPSD	CCLE	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	P54132	BLM	P49841	GSK3B	S714	V721T	721	Missense	distal	7	no	11.395	10.910	EPSD	CCLE	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	E9PAV3	NACA	P49841	GSK3B	S506	T500I	500	Missense	distal	-6	no	6.061	6.056	EPSD	CCLE	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	E9PAV3	NACA	P49841	GSK3B	T879	P886A	886	Missense	distal	7	no	5.687	6.098	EPSD	CCLE	6.007	Gain
CMGC_GSK_GSK3B_ST	E9PAV3	NACA	P49841	GSK3B	T969	A967T	967	Missense	proximal	-2	no	6.079	6.440	EPSD	CCLE	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	E9PAV3	NACA	P49841	GSK3B	S972	A967T	967	Missense	distal	-5	no	6.414	6.425	EPSD	CCLE	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	E9PAV3	NACA	P49841	GSK3B	T987	P994L	994	Missense	distal	7	no	6.921	6.970	EPSD	CCLE	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	E9PAV3	NACA	P49841	GSK3B	T992	P996H	996	Missense	distal	4	no	6.254	5.469	EPSD	CCLE	6.007	Loss
CMGC_GSK_GSK3B_ST	E9PAV3	NACA	P49841	GSK3B	T992	P994L	994	Missense	proximal	2	no	6.254	5.870	EPSD	CCLE	6.007	Loss
CMGC_GSK_GSK3B_ST	E9PAV3	NACA	P49841	GSK3B	S995	P996H	996	Missense	proximal	1	no	6.854	3.153	EPSD	CCLE	6.007	Loss
CMGC_GSK_GSK3B_ST	E9PAV3	NACA	P49841	GSK3B	S995	P994L	994	Missense	proximal	-1	no	6.854	6.723	EPSD	CCLE	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	E9PAV3	NACA	P49841	GSK3B	S1018	A1025S	1025	Missense	distal	7	no	10.603	10.256	EPSD	CCLE	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	E9PAV3	NACA	P49841	GSK3B	S1022	P1029S	1029	Missense	distal	7	no	8.912	8.975	EPSD	CCLE	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	E9PAV3	NACA	P49841	GSK3B	S1022	A1025S	1025	Missense	distal	3	no	8.912	9.249	EPSD	CCLE	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	E9PAV3	NACA	P49841	GSK3B	S1042	P1036L	1036	Missense	distal	-6	no	10.152	10.130	EPSD	CCLE	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	E9PAV3	NACA	P49841	GSK3B	T1059	P1065L	1065	Missense	distal	6	no	7.536	7.529	EPSD	CCLE	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	E9PAV3	NACA	P49841	GSK3B	T1059	P1060S	1060	Missense	proximal	1	no	7.536	3.691	EPSD	CCLE	6.007	Loss
CMGC_GSK_GSK3B_ST	E9PAV3	NACA	P49841	GSK3B	T1059	T1058R	1058	Missense	proximal	-1	no	7.536	7.474	EPSD	CCLE	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	E9PAV3	NACA	P49841	GSK3B	S1066	P1065L	1065	Missense	proximal	-1	no	6.153	6.022	EPSD	CCLE	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	E9PAV3	NACA	P49841	GSK3B	S1066	P1060S	1060	Missense	distal	-6	no	6.153	6.132	EPSD	CCLE	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	E9PAV3	NACA	P49841	GSK3B	T1081	P1088S	1088	Missense	distal	7	no	6.852	6.915	EPSD	CCLE	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	E9PAV3	NACA	P49841	GSK3B	T1081	P1082H	1082	Missense	proximal	1	no	6.852	3.151	EPSD	CCLE	6.007	Loss
CMGC_GSK_GSK3B_ST	E9PAV3	NACA	P49841	GSK3B	T1081	A1079G	1079	Missense	proximal	-2	no	6.852	7.069	EPSD	CCLE	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	E9PAV3	NACA	P49841	GSK3B	T1081	S1075F	1075	Missense	distal	-6	no	6.852	6.798	EPSD	CCLE	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	E9PAV3	NACA	P49841	GSK3B	S1089	P1088S	1088	Missense	proximal	-1	no	6.241	6.185	EPSD	CCLE	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	E9PAV3	NACA	P49841	GSK3B	S1089	P1082H	1082	Missense	distal	-7	no	6.241	6.261	EPSD	CCLE	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	E9PAV3	NACA	P49841	GSK3B	T1151	P1157R	1157	Missense	distal	6	no	8.872	8.866	EPSD	CCLE	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	E9PAV3	NACA	P49841	GSK3B	T1155	P1159S	1159	Missense	distal	4	no	6.403	9.374	EPSD	CCLE	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	E9PAV3	NACA	P49841	GSK3B	T1155	P1157R	1157	Missense	proximal	2	no	6.403	5.977	EPSD	CCLE	6.007	Loss
CMGC_GSK_GSK3B_ST	E9PAV3	NACA	P49841	GSK3B	T1174	A1171V	1171	Missense	distal	-3	no	8.864	9.010	EPSD	CCLE	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	E9PAV3	NACA	P49841	GSK3B	T1174	P1167L	1167	Missense	distal	-7	no	8.864	8.865	EPSD	CCLE	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	E9PAV3	NACA	P49841	GSK3B	T1178	A1171V	1171	Missense	distal	-7	no	6.385	6.384	EPSD	CCLE	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	E9PAV3	NACA	P49841	GSK3B	T1220	P1226L	1226	Missense	distal	6	no	8.880	8.874	EPSD	CCLE	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	E9PAV3	NACA	P49841	GSK3B	T1220	P1225L	1225	Missense	distal	5	no	8.880	7.600	EPSD	CCLE	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	E9PAV3	NACA	P49841	GSK3B	T1224	P1226L	1226	Missense	proximal	2	no	6.380	5.996	EPSD	CCLE	6.007	Loss
CMGC_GSK_GSK3B_ST	E9PAV3	NACA	P49841	GSK3B	T1224	P1225L	1225	Missense	proximal	1	no	6.380	3.520	EPSD	CCLE	6.007	Loss
CMGC_GSK_GSK3B_ST	E9PAV3	NACA	P49841	GSK3B	S1236	P1237T	1237	Missense	proximal	1	no	7.257	4.066	EPSD	CCLE	6.007	Loss
CMGC_GSK_GSK3B_ST	E9PAV3	NACA	P49841	GSK3B	T1243	A1246V	1246	Missense	distal	3	no	8.899	9.028	EPSD	CCLE	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	E9PAV3	NACA	P49841	GSK3B	T1243	A1245T	1245	Missense	proximal	2	no	8.899	9.018	EPSD	CCLE	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	E9PAV3	NACA	P49841	GSK3B	T1243	P1237T	1237	Missense	distal	-6	no	8.899	8.820	EPSD	CCLE	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	E9PAV3	NACA	P49841	GSK3B	T1247	A1246V	1246	Missense	proximal	-1	no	6.704	6.907	EPSD	CCLE	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	E9PAV3	NACA	P49841	GSK3B	T1247	A1245T	1245	Missense	proximal	-2	no	6.704	7.066	EPSD	CCLE	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	E9PAV3	NACA	P49841	GSK3B	S1250	A1246V	1246	Missense	distal	-4	no	6.698	6.624	EPSD	CCLE	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	E9PAV3	NACA	P49841	GSK3B	S1250	A1245T	1245	Missense	distal	-5	no	6.698	6.709	EPSD	CCLE	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	E9PAV3	NACA	P49841	GSK3B	T1265	P1272L	1272	Missense	distal	7	no	6.791	6.840	EPSD	CCLE	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	E9PAV3	NACA	P49841	GSK3B	T1265	P1267K	1267	Missense	proximal	2	no	6.791	6.300	EPSD	CCLE	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	E9PAV3	NACA	P49841	GSK3B	S1304	T1311I	1311	Missense	distal	7	no	6.683	7.077	EPSD	CCLE	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	E9PAV3	NACA	P49841	GSK3B	T1311	T1311I	1311	Missense	central	0	yes	6.691	0.000	EPSD	CCLE	6.007	Loss
CMGC_GSK_GSK3B_ST	E9PAV3	NACA	P49841	GSK3B	T1316	P1320Q	1320	Missense	distal	4	no	6.283	5.691	EPSD	CCLE	6.007	Loss
CMGC_GSK_GSK3B_ST	E9PAV3	NACA	P49841	GSK3B	T1316	P1320A	1320	Missense	distal	4	no	6.283	6.843	EPSD	CCLE	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	E9PAV3	NACA	P49841	GSK3B	T1316	T1311I	1311	Missense	distal	-5	no	6.283	6.467	EPSD	CCLE	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	E9PAV3	NACA	P49841	GSK3B	S1319	P1320Q	1320	Missense	proximal	1	no	9.848	6.580	EPSD	CCLE	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	E9PAV3	NACA	P49841	GSK3B	S1319	P1320A	1320	Missense	proximal	1	no	9.848	6.116	EPSD	CCLE	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	E9PAV3	NACA	P49841	GSK3B	S1323	P1320Q	1320	Missense	distal	-3	no	6.219	6.366	EPSD	CCLE	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	E9PAV3	NACA	P49841	GSK3B	S1323	P1320A	1320	Missense	distal	-3	no	6.219	6.356	EPSD	CCLE	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	E9PAV3	NACA	P49841	GSK3B	T1339	P1343S	1343	Missense	distal	4	no	5.526	8.497	EPSD	CCLE	6.007	Gain
CMGC_GSK_GSK3B_ST	E9PAV3	NACA	P49841	GSK3B	S1342	P1343H	1343	Missense	proximal	1	no	8.618	4.918	EPSD	CCLE	6.007	Loss
CMGC_GSK_GSK3B_ST	E9PAV3	NACA	P49841	GSK3B	S1342	P1343S	1343	Missense	proximal	1	no	8.618	4.773	EPSD	CCLE	6.007	Loss
CMGC_GSK_GSK3B_ST	E9PAV3	NACA	P49841	GSK3B	T1385	A1383V	1383	Missense	proximal	-2	no	5.738	6.040	EPSD	CCLE	6.007	Gain
CMGC_GSK_GSK3B_ST	E9PAV3	NACA	P49841	GSK3B	S1388	A1383V	1383	Missense	distal	-5	no	7.402	7.704	EPSD	CCLE	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	E9PAV3	NACA	P49841	GSK3B	S1404	P1405S	1405	Missense	proximal	1	no	8.035	4.190	EPSD	CCLE	6.007	Loss
CMGC_GSK_GSK3B_ST	E9PAV3	NACA	P49841	GSK3B	S1411	P1405S	1405	Missense	distal	-6	no	7.716	7.695	EPSD	CCLE	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	E9PAV3	NACA	P49841	GSK3B	T1434	P1435L	1435	Missense	proximal	1	no	6.725	3.864	EPSD	CCLE	6.007	Loss
CMGC_GSK_GSK3B_ST	E9PAV3	NACA	P49841	GSK3B	T1573	K1568R	1568	Missense	distal	-5	no	5.938	6.435	EPSD	CCLE	6.007	Gain
CMGC_GSK_GSK3B_ST	E9PAV3	NACA	P49841	GSK3B	S1581	P1574A	1574	Missense	distal	-7	no	6.073	6.097	EPSD	CCLE	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	E9PAV3	NACA	P49841	GSK3B	S1607	P1614R	1614	Missense	distal	7	no	7.135	7.637	EPSD	CCLE	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	E9PAV3	NACA	P49841	GSK3B	S1609	P1614R	1614	Missense	distal	5	no	7.811	7.174	EPSD	CCLE	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	E9PAV3	NACA	P49841	GSK3B	T1615	P1622L	1622	Missense	distal	7	no	6.387	6.436	EPSD	CCLE	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	E9PAV3	NACA	P49841	GSK3B	T1615	T1620I	1620	Missense	distal	5	no	6.387	5.743	EPSD	CCLE	6.007	Loss
CMGC_GSK_GSK3B_ST	E9PAV3	NACA	P49841	GSK3B	T1615	P1614R	1614	Missense	proximal	-1	no	6.387	6.193	EPSD	CCLE	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	E9PAV3	NACA	P49841	GSK3B	T1620	E1625K	1625	Missense	distal	5	no	7.542	6.675	EPSD	CCLE	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	E9PAV3	NACA	P49841	GSK3B	T1620	P1622L	1622	Missense	proximal	2	no	7.542	7.158	EPSD	CCLE	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	E9PAV3	NACA	P49841	GSK3B	T1620	T1620I	1620	Missense	central	0	yes	7.542	0.000	EPSD	CCLE	6.007	Loss
CMGC_GSK_GSK3B_ST	E9PAV3	NACA	P49841	GSK3B	T1620	P1614R	1614	Missense	distal	-6	no	7.542	7.464	EPSD	CCLE	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	E9PAV3	NACA	P49841	GSK3B	S1623	P1628S	1628	Missense	distal	5	no	7.454	6.500	EPSD	CCLE	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	E9PAV3	NACA	P49841	GSK3B	S1623	E1625K	1625	Missense	proximal	2	no	7.454	7.494	EPSD	CCLE	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	E9PAV3	NACA	P49841	GSK3B	S1623	P1622L	1622	Missense	proximal	-1	no	7.454	7.323	EPSD	CCLE	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	E9PAV3	NACA	P49841	GSK3B	S1623	T1620I	1620	Missense	distal	-3	no	7.454	7.543	EPSD	CCLE	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	E9PAV3	NACA	P49841	GSK3B	T1630	A1632V	1632	Missense	proximal	2	no	6.927	6.650	EPSD	CCLE	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	E9PAV3	NACA	P49841	GSK3B	T1630	P1628S	1628	Missense	proximal	-2	no	6.927	6.670	EPSD	CCLE	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	E9PAV3	NACA	P49841	GSK3B	T1630	E1625K	1625	Missense	distal	-5	no	6.927	6.696	EPSD	CCLE	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	E9PAV3	NACA	P49841	GSK3B	S1639	V1642E	1642	Missense	distal	3	no	10.191	10.380	EPSD	CCLE	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	E9PAV3	NACA	P49841	GSK3B	S1639	A1632V	1632	Missense	distal	-7	no	10.191	10.190	EPSD	CCLE	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	E9PAV3	NACA	P49841	GSK3B	T1643	S1650C	1650	Missense	distal	7	no	7.640	8.032	EPSD	CCLE	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	E9PAV3	NACA	P49841	GSK3B	T1643	K1648R	1648	Missense	distal	5	no	7.640	8.515	EPSD	CCLE	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	E9PAV3	NACA	P49841	GSK3B	T1643	V1642E	1642	Missense	proximal	-1	no	7.640	7.580	EPSD	CCLE	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	E9PAV3	NACA	P49841	GSK3B	S1646	S1650C	1650	Missense	distal	4	no	7.207	1.074	EPSD	CCLE	6.007	Loss
CMGC_GSK_GSK3B_ST	E9PAV3	NACA	P49841	GSK3B	S1646	K1648R	1648	Missense	proximal	2	no	7.207	7.273	EPSD	CCLE	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	E9PAV3	NACA	P49841	GSK3B	S1646	V1642E	1642	Missense	distal	-4	no	7.207	7.843	EPSD	CCLE	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	E9PAV3	NACA	P49841	GSK3B	S1650	S1650C	1650	Missense	central	0	yes	6.568	0.000	EPSD	CCLE	6.007	Loss
CMGC_GSK_GSK3B_ST	E9PAV3	NACA	P49841	GSK3B	S1650	K1648R	1648	Missense	proximal	-2	no	6.568	6.586	EPSD	CCLE	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	E9PAV3	NACA	P49841	GSK3B	S1653	S1650C	1650	Missense	distal	-3	no	7.095	7.198	EPSD	CCLE	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	E9PAV3	NACA	P49841	GSK3B	S1653	K1648R	1648	Missense	distal	-5	no	7.095	7.592	EPSD	CCLE	6.007	Up-regulation
CMGC_GSK_GSK3B_ST	E9PAV3	NACA	P49841	GSK3B	S1805	P1801H	1801	Missense	distal	-4	no	7.237	6.713	EPSD	CCLE	6.007	Down-regulation
CMGC_GSK_GSK3B_ST	Q92837	FRAT1	P49841	GSK3B	S179	R180H	180	Missense	proximal	1	no	6.132	4.751	EPSD	CCLE	6.007	Loss
CAMK_MAPKAPK_MK2_MAPKAPK3_ST	Q8N5C8	TAB3	Q16644	MAPKAPK3	S82	S82R	82	Missense	central	0	yes	0.013	0.000	EPSD	CCLE	0.011	Loss
CAMK_MAPKAPK_MK2_MAPKAPK3_ST	Q8N5C8	TAB3	Q16644	MAPKAPK3	S359	S359P	359	Missense	central	0	yes	0.014	0.000	EPSD	CCLE	0.011	Loss
CAMK_MAPKAPK_MK2_MAPKAPK3_ST	Q14457	BECN1	Q16644	MAPKAPK3	S90	S93N	93	Missense	distal	3	no	0.026	0.024	PhosphoSitePlus	CCLE	0.011	Down-regulation
TK_Tec_BMX_Y	Q07912	TNK2	P51813	BMX	Y284	H289Y	289	Missense	distal	5	no	2.441	2.684	EPSD	CCLE	2.549	Gain
TK_Tec_BMX_Y	Q07912	TNK2	P51813	BMX	Y859	P866S	866	Missense	distal	7	no	4.766	4.720	EPSD;PhosphoSitePlus	CCLE	2.549	Down-regulation
TK_Tec_BMX_Y	Q07912	TNK2	P51813	BMX	Y860	P866S	866	Missense	distal	6	no	4.769	4.766	PhosphoSitePlus;EPSD	CCLE	2.549	Down-regulation
Other_PLK_PLK2_PLK2_ST	Q9HC77	CENPJ	Q9NYY3	PLK2	S131	Y138N	138	Missense	distal	7	no	14.944	16.544	EPSD	CCLE	13.807	Up-regulation
Other_PLK_PLK2_PLK2_ST	O15350	TP73	Q9NYY3	PLK2	S471	S477L	477	Missense	distal	6	no	15.653	13.801	EPSD	CCLE	13.807	Loss
Other_PLK_PLK2_PLK2_ST	O43852	CALU	Q9NYY3	PLK2	S44	V38F	38	Missense	distal	-6	no	22.199	22.529	PhosphoSitePlus;EPSD	CCLE	13.807	Up-regulation
Other_PLK_PLK2_PLK2_ST	Q16143	SNCB	Q9NYY3	PLK2	S118	P123S	123	Missense	distal	5	no	13.950	14.054	PhosphoSitePlus	CCLE	13.807	Up-regulation
Other_PLK_PLK2_PLK2_ST	P53350	PLK1	Q9NYY3	PLK2	T366	G367A	367	Missense	proximal	1	no	17.311	16.824	EPSD	CCLE	13.807	Down-regulation
Other_PLK_PLK2_PLK2_ST	P53350	PLK1	Q9NYY3	PLK2	S578	R579W	579	Missense	proximal	1	no	14.998	14.325	EPSD	CCLE	13.807	Down-regulation
Other_PLK_PLK2_PLK2_ST	P53350	PLK1	Q9NYY3	PLK2	S578	R581C	581	Missense	distal	3	no	14.998	17.088	EPSD	CCLE	13.807	Up-regulation
TKL_RAF_RAF_ARAF_ST	Q92934	BAD	P10398	ARAF	S75	H73Q	73	Missense	proximal	-2	no	6.566	6.628	PhosphoSitePlus;EPSD	CCLE	2.916	Up-regulation
TKL_RAF_RAF_ARAF_ST	Q92934	BAD	P10398	ARAF	S75	R70W	70	Missense	distal	-5	no	6.566	6.453	PhosphoSitePlus;EPSD	CCLE	2.916	Down-regulation
TKL_RAF_RAF_ARAF_ST	Q15599	SLC9A3R2	P10398	ARAF	S303	A306V	306	Missense	distal	3	no	6.575	6.560	PhosphoSitePlus	CCLE	2.916	Down-regulation
CMGC_DYRK_DYRK1_DYRK1B_ST	P20823	HNF1A	Q9Y463	DYRK1B	S304	S303N	303	Missense	proximal	-1	no	0.065	0.064	EPSD	CCLE	0.062	Down-regulation
CMGC_DYRK_DYRK1_DYRK1B_ST	O75533	SF3B1	Q9Y463	DYRK1B	S541	L536I	536	Missense	distal	-5	no	0.071	0.070	EPSD	CCLE	0.062	Down-regulation
CAMK_MAPKAPK_MNK_MKNK2_ST	P23246	SFPQ	Q9HBH9	MKNK2	S225	G223A	223	Missense	proximal	-2	no	19.472	19.962	EPSD	CCLE	18.660	Up-regulation
CAMK_MAPKAPK_MNK_MKNK2_ST	P23246	SFPQ	Q9HBH9	MKNK2	S379	R376F	376	Missense	distal	-3	no	20.561	19.746	EPSD	CCLE	18.660	Down-regulation
CAMK_MAPKAPK_MNK_MKNK2_ST	O43597	SPRY2	Q9HBH9	MKNK2	S112	P106R	106	Missense	distal	-6	no	31.862	31.855	PhosphoSitePlus;EPSD	CCLE	18.660	Down-regulation
CAMK_MAPKAPK_MNK_MKNK2_ST	P06730	EIF4E	Q9HBH9	MKNK2	T203	H200Q	200	Missense	distal	-3	no	19.135	20.020	EPSD	CCLE	18.660	Up-regulation
CAMK_MAPKAPK_MNK_MKNK2_ST	Q15149	PLEC	Q9HBH9	MKNK2	S720	A722T	722	Missense	proximal	2	no	18.985	19.226	EPSD	CCLE	18.660	Up-regulation
CAMK_MAPKAPK_MNK_MKNK2_ST	Q15149	PLEC	Q9HBH9	MKNK2	S1077	G1084R	1084	Missense	distal	7	no	21.422	21.275	EPSD	CCLE	18.660	Down-regulation
CAMK_MAPKAPK_MNK_MKNK2_ST	Q15149	PLEC	Q9HBH9	MKNK2	S1077	A1080T	1080	Missense	distal	3	no	21.422	21.421	EPSD	CCLE	18.660	Down-regulation
CAMK_MAPKAPK_MNK_MKNK2_ST	Q15149	PLEC	Q9HBH9	MKNK2	S2833	S2833N	2833	Missense	central	0	yes	20.446	0.000	EPSD	CCLE	18.660	Loss
CAMK_MAPKAPK_MNK_MKNK2_ST	Q15149	PLEC	Q9HBH9	MKNK2	S3319	P3321S	3321	Missense	proximal	2	no	21.037	20.155	EPSD	CCLE	18.660	Down-regulation
CAMK_MAPKAPK_MNK_MKNK2_ST	Q15149	PLEC	Q9HBH9	MKNK2	S3322	P3321S	3321	Missense	proximal	-1	no	20.899	21.128	EPSD	CCLE	18.660	Up-regulation
CAMK_MAPKAPK_MNK_MKNK2_ST	Q15149	PLEC	Q9HBH9	MKNK2	T3988	E3990V	3990	Missense	proximal	2	no	20.047	20.695	EPSD	CCLE	18.660	Up-regulation
CAMK_MAPKAPK_MNK_MKNK2_ST	Q15149	PLEC	Q9HBH9	MKNK2	S4271	R4276H	4276	Missense	distal	5	no	20.075	20.701	EPSD	CCLE	18.660	Up-regulation
CAMK_MAPKAPK_MNK_MKNK2_ST	Q15149	PLEC	Q9HBH9	MKNK2	S4271	R4265Q	4265	Missense	distal	-6	no	20.075	20.045	EPSD	CCLE	18.660	Down-regulation
CAMK_MAPKAPK_MNK_MKNK2_ST	Q15149	PLEC	Q9HBH9	MKNK2	T4628	R4635W	4635	Missense	distal	7	no	19.482	19.378	EPSD	CCLE	18.660	Down-regulation
CAMK_MAPKAPK_MNK_MKNK2_ST	Q15149	PLEC	Q9HBH9	MKNK2	T4628	S4626F	4626	Missense	proximal	-2	no	19.482	17.863	EPSD	CCLE	18.660	Loss
CAMK_MAPKAPK_MNK_MKNK2_ST	Q15149	PLEC	Q9HBH9	MKNK2	S4630	G4637S	4637	Missense	distal	7	no	18.991	18.995	EPSD	CCLE	18.660	Up-regulation
CAMK_MAPKAPK_MNK_MKNK2_ST	Q15149	PLEC	Q9HBH9	MKNK2	S4630	R4635W	4635	Missense	distal	5	no	18.991	18.649	EPSD	CCLE	18.660	Loss
CAMK_MAPKAPK_MNK_MKNK2_ST	Q15149	PLEC	Q9HBH9	MKNK2	S4630	S4626F	4626	Missense	distal	-4	no	18.991	18.677	EPSD	CCLE	18.660	Down-regulation
CAMK_MAPKAPK_MNK_MKNK2_ST	Q15149	PLEC	Q9HBH9	MKNK2	S4642	G4647D	4647	Missense	distal	5	no	30.335	27.504	PhosphoSitePlus	CCLE	18.660	Down-regulation
CAMK_MAPKAPK_MNK_MKNK2_ST	Q15149	PLEC	Q9HBH9	MKNK2	S4642	A4645T	4645	Missense	distal	3	no	30.335	30.334	PhosphoSitePlus	CCLE	18.660	Down-regulation
CAMK_MAPKAPK_MNK_MKNK2_ST	Q15149	PLEC	Q9HBH9	MKNK2	S4642	G4637S	4637	Missense	distal	-5	no	30.335	30.221	PhosphoSitePlus	CCLE	18.660	Down-regulation
CAMK_MAPKAPK_MNK_MKNK2_ST	Q15149	PLEC	Q9HBH9	MKNK2	S4642	R4635W	4635	Missense	distal	-7	no	30.335	29.952	PhosphoSitePlus	CCLE	18.660	Down-regulation
CAMK_MAPKAPK_MNK_MKNK2_ST	Q15149	PLEC	Q9HBH9	MKNK2	T4653	S4657A	4657	Missense	distal	4	no	18.995	18.445	EPSD	CCLE	18.660	Loss
CAMK_MAPKAPK_MNK_MKNK2_ST	Q15149	PLEC	Q9HBH9	MKNK2	T4653	M4652V	4652	Missense	proximal	-1	no	18.995	18.769	EPSD	CCLE	18.660	Down-regulation
CAMK_MAPKAPK_MNK_MKNK2_ST	Q15149	PLEC	Q9HBH9	MKNK2	T4653	G4647D	4647	Missense	distal	-6	no	18.995	18.860	EPSD	CCLE	18.660	Down-regulation
CAMK_MAPKAPK_MNK_MKNK2_ST	Q15149	PLEC	Q9HBH9	MKNK2	S4657	S4657A	4657	Missense	central	0	yes	22.016	0.000	EPSD	CCLE	18.660	Loss
CAMK_MAPKAPK_MNK_MKNK2_ST	Q15149	PLEC	Q9HBH9	MKNK2	S4657	M4652V	4652	Missense	distal	-5	no	22.016	21.874	EPSD	CCLE	18.660	Down-regulation
CAMK_MAPKAPK_MNK_MKNK2_ST	Q15149	PLEC	Q9HBH9	MKNK2	S4658	S4657A	4657	Missense	proximal	-1	no	20.966	20.708	EPSD	CCLE	18.660	Down-regulation
CAMK_MAPKAPK_MNK_MKNK2_ST	Q15149	PLEC	Q9HBH9	MKNK2	S4658	M4652V	4652	Missense	distal	-6	no	20.966	20.912	EPSD	CCLE	18.660	Down-regulation
CAMK_MAPKAPK_MNK_MKNK2_ST	Q15149	PLEC	Q9HBH9	MKNK2	S4661	S4657A	4657	Missense	distal	-4	no	20.053	19.069	EPSD	CCLE	18.660	Down-regulation
CAMK_MAPKAPK_MNK_MKNK2_ST	Q15149	PLEC	Q9HBH9	MKNK2	S4662	S4657A	4657	Missense	distal	-5	no	19.122	19.033	EPSD	CCLE	18.660	Down-regulation
CAMK_PIM_PIM3_ST	Q92934	BAD	Q86V86	PIM3	S34	S32L	32	Missense	proximal	-2	no	4.013	4.357	EPSD	CCLE	3.716	Up-regulation
CAMK_PIM_PIM3_ST	Q92934	BAD	Q86V86	PIM3	S75	H73Q	73	Missense	proximal	-2	no	9.418	9.363	PhosphoSitePlus	CCLE	3.716	Down-regulation
CAMK_PIM_PIM3_ST	Q92934	BAD	Q86V86	PIM3	S75	R70W	70	Missense	distal	-5	no	9.418	7.979	PhosphoSitePlus	CCLE	3.716	Down-regulation
CAMK_PIM_PIM3_ST	P35568	IRS1	Q86V86	PIM3	S270	S273L	273	Missense	distal	3	no	4.559	4.829	EPSD	CCLE	3.716	Up-regulation
CAMK_PIM_PIM3_ST	P35568	IRS1	Q86V86	PIM3	T305	R304H	304	Missense	proximal	-1	no	4.386	4.143	EPSD	CCLE	3.716	Down-regulation
CAMK_PIM_PIM3_ST	P35568	IRS1	Q86V86	PIM3	T305	R302Q	302	Missense	distal	-3	no	4.386	2.846	EPSD	CCLE	3.716	Loss
CAMK_PIM_PIM3_ST	P35568	IRS1	Q86V86	PIM3	S307	A314D	314	Missense	distal	7	no	4.171	4.299	EPSD	CCLE	3.716	Up-regulation
CAMK_PIM_PIM3_ST	P35568	IRS1	Q86V86	PIM3	S307	R304H	304	Missense	distal	-3	no	4.171	2.682	EPSD	CCLE	3.716	Loss
CAMK_PIM_PIM3_ST	P35568	IRS1	Q86V86	PIM3	S307	R302Q	302	Missense	distal	-5	no	4.171	3.803	EPSD	CCLE	3.716	Down-regulation
CAMK_PIM_PIM3_ST	P35568	IRS1	Q86V86	PIM3	T309	A314D	314	Missense	distal	5	no	4.582	4.436	EPSD	CCLE	3.716	Down-regulation
CAMK_PIM_PIM3_ST	P35568	IRS1	Q86V86	PIM3	T309	R304H	304	Missense	distal	-5	no	4.582	3.376	EPSD	CCLE	3.716	Loss
CAMK_PIM_PIM3_ST	P35568	IRS1	Q86V86	PIM3	T309	R302Q	302	Missense	distal	-7	no	4.582	4.871	EPSD	CCLE	3.716	Up-regulation
CAMK_PIM_PIM3_ST	P35568	IRS1	Q86V86	PIM3	T397	T403P	403	Missense	distal	6	no	4.342	4.163	EPSD	CCLE	3.716	Down-regulation
CAMK_PIM_PIM3_ST	P35568	IRS1	Q86V86	PIM3	S398	T403P	403	Missense	distal	5	no	4.113	4.020	EPSD	CCLE	3.716	Down-regulation
CAMK_PIM_PIM3_ST	P35568	IRS1	Q86V86	PIM3	T403	T403P	403	Missense	central	0	yes	4.250	0.000	EPSD	CCLE	3.716	Loss
CAMK_PIM_PIM3_ST	P35568	IRS1	Q86V86	PIM3	T525	P532S	532	Missense	distal	7	no	4.253	4.462	EPSD	CCLE	3.716	Up-regulation
CAMK_PIM_PIM3_ST	P35568	IRS1	Q86V86	PIM3	S527	P532S	532	Missense	distal	5	no	3.958	3.872	EPSD	CCLE	3.716	Down-regulation
CAMK_PIM_PIM3_ST	P35568	IRS1	Q86V86	PIM3	T579	T579I	579	Missense	central	0	yes	4.333	0.000	EPSD	CCLE	3.716	Loss
CAMK_PIM_PIM3_ST	P35568	IRS1	Q86V86	PIM3	T579	V577M	577	Missense	proximal	-2	no	4.333	4.452	EPSD	CCLE	3.716	Up-regulation
CAMK_PIM_PIM3_ST	P35568	IRS1	Q86V86	PIM3	T793	S795Y	795	Missense	proximal	2	no	4.369	4.436	EPSD	CCLE	3.716	Up-regulation
CAMK_PIM_PIM3_ST	P35568	IRS1	Q86V86	PIM3	T793	L791P	791	Missense	proximal	-2	no	4.369	4.153	EPSD	CCLE	3.716	Down-regulation
CAMK_PIM_PIM3_ST	P35568	IRS1	Q86V86	PIM3	S794	S795Y	795	Missense	proximal	1	no	4.487	4.777	EPSD	CCLE	3.716	Up-regulation
CAMK_PIM_PIM3_ST	P35568	IRS1	Q86V86	PIM3	S794	L791P	791	Missense	distal	-3	no	4.487	4.060	EPSD	CCLE	3.716	Down-regulation
CAMK_PIM_PIM3_ST	P35568	IRS1	Q86V86	PIM3	S795	S795Y	795	Missense	central	0	yes	4.451	0.000	EPSD	CCLE	3.716	Loss
CAMK_PIM_PIM3_ST	P35568	IRS1	Q86V86	PIM3	S795	L791P	791	Missense	distal	-4	no	4.451	3.998	EPSD	CCLE	3.716	Down-regulation
CAMK_PIM_PIM3_ST	P35568	IRS1	Q86V86	PIM3	S1101	S1105F	1105	Missense	distal	4	no	8.897	9.037	PhosphoSitePlus	CCLE	3.716	Up-regulation
CAMK_PIM_PIM3_ST	P35568	IRS1	Q86V86	PIM3	S1105	S1105F	1105	Missense	central	0	yes	4.113	0.000	EPSD	CCLE	3.716	Loss
CAMK_PIM_PIM3_ST	P35568	IRS1	Q86V86	PIM3	T1107	S1105F	1105	Missense	proximal	-2	no	3.675	3.991	EPSD	CCLE	3.716	Gain
TK_Src_SrcB_LCK_Y	Q9NP31	SH2D2A	P06239	LCK	Y290	A291P	291	Missense	proximal	1	no	5.581	5.635	PhosphoSitePlus;EPSD	CCLE	5.050	Up-regulation
TK_Src_SrcB_LCK_Y	Q9NP31	SH2D2A	P06239	LCK	Y290	A288P	288	Missense	proximal	-2	no	5.581	5.692	PhosphoSitePlus;EPSD	CCLE	5.050	Up-regulation
TK_Src_SrcB_LCK_Y	Q9NP31	SH2D2A	P06239	LCK	Y305	V308L	308	Missense	distal	3	no	7.758	7.956	EPSD;PhosphoSitePlus	CCLE	5.050	Up-regulation
TK_Src_SrcB_LCK_Y	P06127	CD5	P06239	LCK	Y487	D480G	480	Missense	distal	-7	no	6.371	6.231	EPSD;PhosphoSitePlus	CCLE	5.050	Down-regulation
TK_Src_SrcB_LCK_Y	Q9H204	MED28	P06239	LCK	Y64	N66S	66	Missense	proximal	2	no	6.252	6.583	PhosphoSitePlus	CCLE	5.050	Up-regulation
TK_Src_SrcB_LCK_Y	P16885	PLCG2	P06239	LCK	Y759	I765V	765	Missense	distal	6	no	5.707	5.763	EPSD;PhosphoSitePlus	CCLE	5.050	Up-regulation
TK_Src_SrcB_LCK_Y	P16885	PLCG2	P06239	LCK	Y1197	Q1202R	1202	Missense	distal	5	no	6.477	6.479	EPSD;PhosphoSitePlus	CCLE	5.050	Up-regulation
TK_Src_SrcB_LCK_Y	P20963	CD247	P06239	LCK	Y83	V85I	85	Missense	proximal	2	no	5.558	5.137	EPSD	CCLE	5.050	Down-regulation
TK_Src_SrcB_LCK_Y	P20963	CD247	P06239	LCK	Y142	A148V	148	Missense	distal	6	no	8.002	8.330	PhosphoSitePlus	CCLE	5.050	Up-regulation
TK_Src_SrcB_LCK_Y	P20963	CD247	P06239	LCK	Y153	A148V	148	Missense	distal	-5	no	7.641	7.259	EPSD	CCLE	5.050	Down-regulation
TK_Src_SrcB_LCK_Y	Q9BWW4	SSBP3	P06239	LCK	Y23	A16T	16	Missense	distal	-7	no	6.465	6.125	EPSD;PhosphoSitePlus	CCLE	5.050	Down-regulation
TK_Src_SrcB_LCK_Y	P52757	CHN2	P06239	LCK	Y153	T160A	160	Missense	distal	7	no	6.775	6.848	PhosphoSitePlus	CCLE	5.050	Up-regulation
TK_Src_SrcB_LCK_Y	P43403	ZAP70	P06239	LCK	Y474	A475G	475	Missense	proximal	1	no	6.933	6.829	EPSD;PhosphoSitePlus	CCLE	5.050	Down-regulation
TK_Src_SrcB_LCK_Y	Q8IWV1	LAX1	P06239	LCK	Y373	V376M	376	Missense	distal	3	no	7.808	8.023	EPSD;PhosphoSitePlus	CCLE	5.050	Up-regulation
TK_Src_SrcB_LCK_Y	P15498	VAV1	P06239	LCK	Y603	M597I	597	Missense	distal	-6	no	5.374	4.467	EPSD	CCLE	5.050	Loss
TK_Src_SrcB_LCK_Y	P29350	PTPN6	P06239	LCK	Y509	K506N	506	Missense	distal	-3	no	5.697	6.576	EPSD	CCLE	5.050	Up-regulation
TK_Src_SrcB_LCK_Y	P29350	PTPN6	P06239	LCK	Y536	P542L	542	Missense	distal	6	no	6.084	6.194	EPSD;PhosphoSitePlus	CCLE	5.050	Up-regulation
TK_Src_SrcB_LCK_Y	P29350	PTPN6	P06239	LCK	Y564	H568Y	568	Missense	distal	4	no	10.692	10.798	PhosphoSitePlus;EPSD	CCLE	5.050	Up-regulation
TK_Src_SrcB_LCK_Y	Q13291	SLAMF1	P06239	LCK	Y269	R263K	263	Missense	distal	-6	no	5.449	5.280	EPSD	CCLE	5.050	Down-regulation
TK_Src_SrcB_LCK_Y	P60484	PTEN	P06239	LCK	Y68	K62Q	62	Missense	distal	-6	no	4.757	5.100	EPSD	CCLE	5.050	Gain
TK_Src_SrcB_LCK_Y	P60484	PTEN	P06239	LCK	Y240	F243V	243	Missense	distal	3	no	6.412	6.492	EPSD;PhosphoSitePlus	CCLE	5.050	Up-regulation
TK_Src_SrcB_LCK_Y	P23743	DGKA	P06239	LCK	Y669	L672I	672	Missense	distal	3	no	5.148	5.003	EPSD	CCLE	5.050	Loss
TK_Src_SrcB_LCK_Y	P15311	EZR	P06239	LCK	Y478	V477L	477	Missense	proximal	-1	no	6.042	5.698	EPSD	CCLE	5.050	Down-regulation
TK_Src_SrcB_LCK_Y	Q9UHD2	TBK1	P06239	LCK	Y153	S151F	151	Missense	proximal	-2	no	5.423	4.856	EPSD	CCLE	5.050	Loss
TK_Src_SrcB_LCK_Y	Q9UHD2	TBK1	P06239	LCK	Y153	V152L	152	Missense	proximal	-1	no	5.423	5.079	EPSD	CCLE	5.050	Down-regulation
TK_Ret_RET_Y	P40763	STAT3	Q15300	RET	Y539	T545I	545	Missense	distal	6	no	30.476	30.119	EPSD	CCLE	28.094	Down-regulation
Other_KIS_UHMK1_ST	P46527	CDKN1B	Q8TAS1	UHMK1	S10	S12I	12	Missense	proximal	2	no	4.134	4.164	PhosphoSitePlus	CCLE	1.522	Up-regulation
Other_KIS_UHMK1_ST	P46527	CDKN1B	Q8TAS1	UHMK1	S83	F87L	87	Missense	distal	4	no	1.366	1.565	EPSD	CCLE	1.522	Gain
Other_IKK_IKBKE_ST	Q96FA3	PELI1	Q14164	IKBKE	T117	V113I	113	Missense	distal	-4	no	77.418	71.908	EPSD	CCLE	71.554	Down-regulation
Other_IKK_IKBKE_ST	O95644	NFATC1	Q14164	IKBKE	S117	R119L	119	Missense	proximal	2	no	97.976	93.483	EPSD;PhosphoSitePlus	CCLE	71.554	Down-regulation
Other_IKK_IKBKE_ST	O95644	NFATC1	Q14164	IKBKE	S117	T123N	123	Missense	distal	6	no	97.976	89.014	EPSD;PhosphoSitePlus	CCLE	71.554	Down-regulation
Other_IKK_IKBKE_ST	O95644	NFATC1	Q14164	IKBKE	S233	R235Q	235	Missense	proximal	2	no	81.204	79.583	EPSD	CCLE	71.554	Down-regulation
Other_IKK_IKBKE_ST	O95644	NFATC1	Q14164	IKBKE	S237	R235Q	235	Missense	proximal	-2	no	55.602	76.140	EPSD	CCLE	71.554	Gain
Other_IKK_IKBKE_ST	O95644	NFATC1	Q14164	IKBKE	S241	R235Q	235	Missense	distal	-6	no	79.048	80.291	EPSD	CCLE	71.554	Up-regulation
Other_IKK_IKBKE_ST	O95644	NFATC1	Q14164	IKBKE	S241	R243C	243	Missense	proximal	2	no	79.048	78.461	EPSD	CCLE	71.554	Down-regulation
Other_IKK_IKBKE_ST	O95644	NFATC1	Q14164	IKBKE	S241	S245I	245	Missense	distal	4	no	79.048	47.831	EPSD	CCLE	71.554	Loss
Other_IKK_IKBKE_ST	O95644	NFATC1	Q14164	IKBKE	S269	N264S	264	Missense	distal	-5	no	82.411	74.897	EPSD	CCLE	71.554	Down-regulation
Other_IKK_IKBKE_ST	O95644	NFATC1	Q14164	IKBKE	S269	R273W	273	Missense	distal	4	no	82.411	75.749	EPSD	CCLE	71.554	Down-regulation
Other_IKK_IKBKE_ST	O95644	NFATC1	Q14164	IKBKE	S359	G358V	358	Missense	proximal	-1	no	78.484	85.397	EPSD	CCLE	71.554	Up-regulation
Other_IKK_IKBKE_ST	O95644	NFATC1	Q14164	IKBKE	S903	I909M	909	Missense	distal	6	no	72.002	84.662	EPSD	CCLE	71.554	Up-regulation
Other_IKK_IKBKE_ST	Q14653	IRF3	Q14164	IKBKE	S386	A384D	384	Missense	proximal	-2	no	95.767	102.763	PhosphoSitePlus;EPSD	CCLE	71.554	Up-regulation
Other_IKK_IKBKE_ST	Q92985	IRF7	Q14164	IKBKE	S53	F47S	47	Missense	distal	-6	no	76.776	76.520	EPSD	CCLE	71.554	Down-regulation
Other_IKK_IKBKE_ST	Q92985	IRF7	Q14164	IKBKE	S471	R467C	467	Missense	distal	-4	no	96.452	89.836	EPSD;PhosphoSitePlus	CCLE	71.554	Down-regulation
Other_IKK_IKBKE_ST	Q92985	IRF7	Q14164	IKBKE	S472	R467C	467	Missense	distal	-5	no	103.179	89.658	EPSD;PhosphoSitePlus	CCLE	71.554	Down-regulation
Other_IKK_IKBKE_ST	P03372	ESR1	Q14164	IKBKE	S104	F97S	97	Missense	distal	-7	no	81.324	80.380	EPSD	CCLE	71.554	Down-regulation
Other_IKK_IKBKE_ST	P98170	XIAP	Q14164	IKBKE	S38	A34G	34	Missense	distal	-4	no	76.505	78.755	EPSD	CCLE	71.554	Up-regulation
Other_IKK_IKBKE_ST	P98170	XIAP	Q14164	IKBKE	S40	A34G	34	Missense	distal	-6	no	76.542	75.719	EPSD	CCLE	71.554	Down-regulation
Other_IKK_IKBKE_ST	P46937	YAP1	Q14164	IKBKE	S419	D421N	421	Missense	proximal	2	no	104.296	108.835	PhosphoSitePlus	CCLE	71.554	Up-regulation
Other_IKK_IKBKE_ST	O00571	DDX3X	Q14164	IKBKE	S86	S86G	86	Missense	central	0	yes	74.019	0.000	EPSD	CCLE	71.554	Loss
Other_IKK_IKBKE_ST	O00571	DDX3X	Q14164	IKBKE	S86	S86R	86	Missense	central	0	yes	74.019	0.000	EPSD	CCLE	71.554	Loss
Other_IKK_IKBKE_ST	O00571	DDX3X	Q14164	IKBKE	S90	S86G	86	Missense	distal	-4	no	72.316	71.862	EPSD	CCLE	71.554	Down-regulation
Other_IKK_IKBKE_ST	O00571	DDX3X	Q14164	IKBKE	S90	S86R	86	Missense	distal	-4	no	72.316	74.859	EPSD	CCLE	71.554	Up-regulation
Other_IKK_IKBKE_ST	O00571	DDX3X	Q14164	IKBKE	T438	T438A	438	Missense	central	0	yes	74.598	0.000	EPSD	CCLE	71.554	Loss
Other_IKK_IKBKE_ST	O00571	DDX3X	Q14164	IKBKE	S489	K491R	491	Missense	proximal	2	no	71.722	72.457	EPSD	CCLE	71.554	Up-regulation
Other_IKK_IKBKE_ST	O00571	DDX3X	Q14164	IKBKE	S492	K491R	491	Missense	proximal	-1	no	75.194	82.149	EPSD	CCLE	71.554	Up-regulation
Other_IKK_IKBKE_ST	O00571	DDX3X	Q14164	IKBKE	S520	E524A	524	Missense	distal	4	no	83.612	90.867	EPSD	CCLE	71.554	Up-regulation
Other_IKK_IKBKE_ST	O00571	DDX3X	Q14164	IKBKE	S606	G607S	607	Missense	proximal	1	no	66.429	77.366	EPSD	CCLE	71.554	Gain
Other_IKK_IKBKE_ST	O00571	DDX3X	Q14164	IKBKE	S610	G607S	607	Missense	distal	-3	no	72.289	70.183	EPSD	CCLE	71.554	Loss
Other_IKK_IKBKE_ST	Q04206	RELA	Q14164	IKBKE	S468	A467V	467	Missense	proximal	-1	no	95.113	101.090	EPSD;PhosphoSitePlus	CCLE	71.554	Up-regulation
Other_IKK_IKBKE_ST	Q04206	RELA	Q14164	IKBKE	S536	S535A	535	Missense	proximal	-1	no	85.327	83.126	PhosphoSitePlus;EPSD	CCLE	71.554	Down-regulation
Other_IKK_IKBKE_ST	O43524	FOXO3	Q14164	IKBKE	S26	R27G	27	Missense	proximal	1	no	72.410	66.749	EPSD	CCLE	71.554	Loss
Other_IKK_IKBKE_ST	O43524	FOXO3	Q14164	IKBKE	S438	R444C	444	Missense	distal	6	no	78.933	74.740	EPSD	CCLE	71.554	Down-regulation
Other_IKK_IKBKE_ST	O43524	FOXO3	Q14164	IKBKE	S442	R444C	444	Missense	proximal	2	no	81.488	80.901	EPSD	CCLE	71.554	Down-regulation
Other_IKK_IKBKE_ST	P49840	GSK3A	Q14164	IKBKE	S401	L395Q	395	Missense	distal	-6	no	78.685	77.134	EPSD	CCLE	71.554	Down-regulation
Other_IKK_IKBKE_ST	Q9UNN5	FAF1	Q14164	IKBKE	S314	A316T	316	Missense	proximal	2	no	77.414	81.349	EPSD	CCLE	71.554	Up-regulation
CMGC_MAPK_p38_MAPK12_ST	Q12959	DLG1	P53778	MAPK12	S100	L101P	101	Missense	proximal	1	no	116.422	133.168	EPSD	CCLE	112.929	Up-regulation
CMGC_MAPK_p38_MAPK12_ST	Q12959	DLG1	P53778	MAPK12	S102	L101P	101	Missense	proximal	-1	no	120.826	121.712	EPSD	CCLE	112.929	Up-regulation
CMGC_MAPK_p38_MAPK12_ST	Q12959	DLG1	P53778	MAPK12	S443	V450G	450	Missense	distal	7	no	145.026	145.757	EPSD;PhosphoSitePlus	CCLE	112.929	Up-regulation
CMGC_MAPK_p38_MAPK12_ST	Q12959	DLG1	P53778	MAPK12	S448	V450G	450	Missense	proximal	2	no	115.530	116.037	EPSD	CCLE	112.929	Up-regulation
CMGC_MAPK_p38_MAPK12_ST	Q12959	DLG1	P53778	MAPK12	S583	R582Q	582	Missense	proximal	-1	no	118.139	117.942	EPSD	CCLE	112.929	Down-regulation
CMGC_MAPK_p38_MAPK12_ST	Q12959	DLG1	P53778	MAPK12	T630	Q628H	628	Missense	proximal	-2	no	118.552	120.984	EPSD	CCLE	112.929	Up-regulation
CMGC_MAPK_p38_MAPK12_ST	Q00613	HSF1	P53778	MAPK12	S237	P243L	243	Missense	distal	6	no	117.218	116.864	EPSD	CCLE	112.929	Down-regulation
CMGC_MAPK_p38_MAPK12_ST	Q00613	HSF1	P53778	MAPK12	S244	P243L	243	Missense	proximal	-1	no	127.884	126.998	EPSD	CCLE	112.929	Down-regulation
CMGC_MAPK_p38_MAPK12_ST	Q00613	HSF1	P53778	MAPK12	S292	R287M	287	Missense	distal	-5	no	125.557	125.560	EPSD	CCLE	112.929	Up-regulation
CMGC_MAPK_p38_MAPK12_ST	Q00613	HSF1	P53778	MAPK12	T369	E371K	371	Missense	proximal	2	no	118.876	119.927	EPSD	CCLE	112.929	Up-regulation
CMGC_MAPK_p38_MAPK12_ST	Q00613	HSF1	P53778	MAPK12	S419	V424M	424	Missense	distal	5	no	129.769	129.999	EPSD	CCLE	112.929	Up-regulation
CMGC_MAPK_p38_MAPK12_ST	P35222	CTNNB1	P53778	MAPK12	T102	G106D	106	Missense	distal	4	no	113.879	114.062	EPSD	CCLE	112.929	Up-regulation
CMGC_MAPK_p38_MAPK12_ST	P10636	MAPT	P53778	MAPK12	T69	A66V	66	Missense	distal	-3	no	139.605	139.042	EPSD	CCLE	112.929	Down-regulation
CMGC_MAPK_p38_MAPK12_ST	P10636	MAPT	P53778	MAPK12	T111	G107V	107	Missense	distal	-4	no	138.577	130.074	EPSD	CCLE	112.929	Down-regulation
CMGC_MAPK_p38_MAPK12_ST	P10636	MAPT	P53778	MAPK12	S228	D221Y	221	Missense	distal	-7	no	119.197	119.757	EPSD	CCLE	112.929	Up-regulation
CMGC_MAPK_p38_MAPK12_ST	P10636	MAPT	P53778	MAPK12	S228	P234S	234	Missense	distal	6	no	119.197	119.501	EPSD	CCLE	112.929	Up-regulation
CMGC_MAPK_p38_MAPK12_ST	P10636	MAPT	P53778	MAPK12	S232	P234S	234	Missense	proximal	2	no	127.513	127.896	EPSD	CCLE	112.929	Up-regulation
CMGC_MAPK_p38_MAPK12_ST	P10636	MAPT	P53778	MAPK12	S238	P234S	234	Missense	distal	-4	no	124.422	128.498	EPSD	CCLE	112.929	Up-regulation
CMGC_MAPK_p38_MAPK12_ST	P10636	MAPT	P53778	MAPK12	S238	D242H	242	Missense	distal	4	no	124.422	123.321	EPSD	CCLE	112.929	Down-regulation
CMGC_MAPK_p38_MAPK12_ST	P10636	MAPT	P53778	MAPK12	T403	K405R	405	Missense	proximal	2	no	126.500	125.987	EPSD	CCLE	112.929	Down-regulation
CMGC_MAPK_p38_MAPK12_ST	P10636	MAPT	P53778	MAPK12	S411	K405R	405	Missense	distal	-6	no	133.123	134.818	EPSD	CCLE	112.929	Up-regulation
CMGC_MAPK_p38_MAPK12_ST	P10636	MAPT	P53778	MAPK12	S438	V442I	442	Missense	distal	4	no	130.470	131.257	EPSD	CCLE	112.929	Up-regulation
CMGC_MAPK_p38_MAPK12_ST	P10636	MAPT	P53778	MAPK12	S508	R511H	511	Missense	distal	3	no	114.644	114.916	EPSD	CCLE	112.929	Up-regulation
CMGC_MAPK_p38_MAPK12_ST	P10636	MAPT	P53778	MAPK12	S512	R511H	511	Missense	proximal	-1	no	126.606	126.702	EPSD	CCLE	112.929	Up-regulation
CMGC_MAPK_p38_MAPK12_ST	P10636	MAPT	P53778	MAPK12	S512	G518S	518	Missense	distal	6	no	126.606	126.637	EPSD	CCLE	112.929	Up-regulation
CMGC_MAPK_p38_MAPK12_ST	P10636	MAPT	P53778	MAPK12	S516	R511H	511	Missense	distal	-5	no	144.771	144.816	EPSD	CCLE	112.929	Up-regulation
CMGC_MAPK_p38_MAPK12_ST	P10636	MAPT	P53778	MAPK12	S516	G518S	518	Missense	proximal	2	no	144.771	145.491	EPSD	CCLE	112.929	Up-regulation
CMGC_MAPK_p38_MAPK12_ST	P10636	MAPT	P53778	MAPK12	S519	G518S	518	Missense	proximal	-1	no	138.829	139.194	EPSD	CCLE	112.929	Up-regulation
CMGC_MAPK_p38_MAPK12_ST	P10636	MAPT	P53778	MAPK12	S519	R526L	526	Missense	distal	7	no	138.829	138.397	EPSD	CCLE	112.929	Down-regulation
CMGC_MAPK_p38_MAPK12_ST	P10636	MAPT	P53778	MAPK12	T522	G518S	518	Missense	distal	-4	no	140.094	140.790	EPSD	CCLE	112.929	Up-regulation
CMGC_MAPK_p38_MAPK12_ST	P10636	MAPT	P53778	MAPK12	T522	R526L	526	Missense	distal	4	no	140.094	140.239	EPSD	CCLE	112.929	Up-regulation
CMGC_MAPK_p38_MAPK12_ST	P10636	MAPT	P53778	MAPK12	S525	R526L	526	Missense	proximal	1	no	-37.533	131.465	EPSD	CCLE	112.929	Gain
CMGC_MAPK_p38_MAPK12_ST	P10636	MAPT	P53778	MAPK12	T529	R526L	526	Missense	distal	-3	no	138.918	138.904	EPSD	CCLE	112.929	Down-regulation
CMGC_MAPK_p38_MAPK12_ST	P10636	MAPT	P53778	MAPK12	S531	R526L	526	Missense	distal	-5	no	115.782	115.716	EPSD	CCLE	112.929	Down-regulation
CMGC_MAPK_p38_MAPK12_ST	P10636	MAPT	P53778	MAPK12	S552	R559H	559	Missense	distal	7	no	133.976	133.833	EPSD	CCLE	112.929	Down-regulation
CMGC_MAPK_p38_MAPK12_ST	P10636	MAPT	P53778	MAPK12	S713	G706V	706	Missense	distal	-7	no	134.253	135.151	EPSD	CCLE	112.929	Up-regulation
CMGC_MAPK_p38_MAPK12_ST	P10636	MAPT	P53778	MAPK12	S713	S717C	717	Missense	distal	4	no	134.253	132.741	EPSD	CCLE	112.929	Down-regulation
CMGC_MAPK_p38_MAPK12_ST	P10636	MAPT	P53778	MAPK12	S721	S717C	717	Missense	distal	-4	no	135.760	127.030	EPSD	CCLE	112.929	Down-regulation
CMGC_MAPK_p38_MAPK12_ST	P10636	MAPT	P53778	MAPK12	S721	S721C	721	Missense	central	0	yes	135.760	0.000	EPSD	CCLE	112.929	Loss
CMGC_MAPK_p38_MAPK12_ST	P10636	MAPT	P53778	MAPK12	S721	H724R	724	Missense	distal	3	no	135.760	135.487	EPSD	CCLE	112.929	Down-regulation
CMGC_MAPK_p38_MAPK12_ST	P10636	MAPT	P53778	MAPK12	T731	H724R	724	Missense	distal	-7	no	114.564	114.926	EPSD	CCLE	112.929	Up-regulation
CMGC_MAPK_p38_MAPK12_ST	P10636	MAPT	P53778	MAPK12	S739	Q741K	741	Missense	proximal	2	no	131.198	132.003	EPSD	CCLE	112.929	Up-regulation
CMGC_MAPK_p38_MAPK12_ST	P10636	MAPT	P53778	MAPK12	T744	Q741K	741	Missense	distal	-3	no	114.728	114.961	EPSD	CCLE	112.929	Up-regulation
CMGC_MAPK_p38_MAPK12_ST	P26045	PTPN3	P53778	MAPK12	S381	E387K	387	Missense	distal	6	no	118.537	119.155	EPSD	CCLE	112.929	Up-regulation
CMGC_MAPK_p38_MAPK12_ST	P07900	HSP90AA1	P53778	MAPK12	S113	G108D	108	Missense	distal	-5	no	116.026	116.140	EPSD	CCLE	112.929	Up-regulation
CMGC_MAPK_p38_MAPK12_ST	P07900	HSP90AA1	P53778	MAPK12	S315	Y309C	309	Missense	distal	-6	no	114.144	117.068	EPSD	CCLE	112.929	Up-regulation
CMGC_MAPK_p38_MAPK12_ST	P07900	HSP90AA1	P53778	MAPK12	T495	E497D	497	Missense	proximal	2	no	117.784	119.208	EPSD	CCLE	112.929	Up-regulation
CMGC_MAPK_p38_MAPK12_ST	P07900	HSP90AA1	P53778	MAPK12	T495	I491T	491	Missense	distal	-4	no	117.784	115.277	EPSD	CCLE	112.929	Down-regulation
CMGC_MAPK_p38_MAPK12_ST	P07900	HSP90AA1	P53778	MAPK12	T645	T645A	645	Missense	central	0	yes	114.013	0.000	EPSD	CCLE	112.929	Loss
CMGC_MAPK_p38_MAPK12_ST	P07900	HSP90AA1	P53778	MAPK12	T645	I642T	642	Missense	distal	-3	no	114.013	113.702	EPSD	CCLE	112.929	Down-regulation
CMGC_MAPK_p38_MAPK12_ST	P30281	CCND3	P53778	MAPK12	S264	S259F	259	Missense	distal	-5	no	126.610	126.215	EPSD	CCLE	112.929	Down-regulation
STE_STE7_MEK4_MAP2K4_ST	P45983	MAPK8	P45985	MAP2K4	T21	K24T	24	Missense	distal	3	no	0.006	0.005	EPSD	CCLE	0.006	Loss
STE_STE7_MEK4_MAP2K4_ST	P45984	MAPK9	P45985	MAP2K4	S412	D414Y	414	Missense	proximal	2	no	0.009	0.010	EPSD	CCLE	0.006	Up-regulation
STE_STE7_MEK4_MAP2K4_ST	P19793	RXRA	P45985	MAP2K4	T82	M77I	77	Missense	distal	-5	no	0.006	0.005	EPSD	CCLE	0.006	Loss
AGC_PDK1_PDPK1_ST	O15530	PDPK1	O15530	PDPK1	S25	C21Y	21	Missense	distal	-4	no	6.654	6.645	EPSD;PhosphoSitePlus	CCLE	3.516	Down-regulation
AGC_PDK1_PDPK1_ST	O15530	PDPK1	O15530	PDPK1	T37	T31A	31	Missense	distal	-6	no	3.906	3.930	EPSD	CCLE	3.516	Up-regulation
AGC_PDK1_PDPK1_ST	O15530	PDPK1	O15530	PDPK1	T37	P42T	42	Missense	distal	5	no	3.906	4.065	EPSD	CCLE	3.516	Up-regulation
AGC_PDK1_PDPK1_ST	Q16512	PKN1	O15530	PDPK1	S374	L368F	368	Missense	distal	-6	no	5.526	5.588	EPSD	CCLE	3.516	Up-regulation
AGC_PDK1_PDPK1_ST	Q16512	PKN1	O15530	PDPK1	S537	A542V	542	Missense	distal	5	no	4.668	4.451	EPSD	CCLE	3.516	Down-regulation
AGC_PDK1_PDPK1_ST	Q16512	PKN1	O15530	PDPK1	S561	G556S	556	Missense	distal	-5	no	4.280	4.292	EPSD	CCLE	3.516	Up-regulation
AGC_PDK1_PDPK1_ST	Q16512	PKN1	O15530	PDPK1	S561	S559L	559	Missense	proximal	-2	no	4.280	4.107	EPSD	CCLE	3.516	Down-regulation
AGC_PDK1_PDPK1_ST	Q16512	PKN1	O15530	PDPK1	S562	G556S	556	Missense	distal	-6	no	4.751	4.779	EPSD	CCLE	3.516	Up-regulation
AGC_PDK1_PDPK1_ST	Q16512	PKN1	O15530	PDPK1	S562	S559L	559	Missense	distal	-3	no	4.751	3.966	EPSD	CCLE	3.516	Down-regulation
AGC_PDK1_PDPK1_ST	Q16512	PKN1	O15530	PDPK1	S566	S559L	559	Missense	distal	-7	no	3.532	2.606	EPSD	CCLE	3.516	Loss
AGC_PDK1_PDPK1_ST	Q16512	PKN1	O15530	PDPK1	S579	S584F	584	Missense	distal	5	no	5.212	3.797	EPSD	CCLE	3.516	Down-regulation
AGC_PDK1_PDPK1_ST	Q16512	PKN1	O15530	PDPK1	T596	P597Q	597	Missense	proximal	1	no	5.235	0.014	EPSD	CCLE	3.516	Loss
AGC_PDK1_PDPK1_ST	Q16512	PKN1	O15530	PDPK1	T774	P779S	779	Missense	distal	5	no	10.248	10.360	EPSD;PhosphoSitePlus	CCLE	3.516	Up-regulation
AGC_PDK1_PDPK1_ST	Q16512	PKN1	O15530	PDPK1	S916	R919C	919	Missense	distal	3	no	5.868	5.765	EPSD	CCLE	3.516	Down-regulation
AGC_PDK1_PDPK1_ST	P08559	PDHA1	O15530	PDPK1	S232	A236V	236	Missense	distal	4	no	4.854	4.637	EPSD;PhosphoSitePlus	CCLE	3.516	Down-regulation
AGC_PDK1_PDPK1_ST	P31751	AKT2	O15530	PDPK1	S126	S130D	130	Missense	distal	4	no	6.928	5.880	EPSD	CCLE	3.516	Down-regulation
AGC_PDK1_PDPK1_ST	P05106	ITGB3	O15530	PDPK1	T779	I783T	783	Missense	distal	4	no	4.971	6.327	PhosphoSitePlus	CCLE	3.516	Up-regulation
AGC_PDK1_PDPK1_ST	P05106	ITGB3	O15530	PDPK1	T779	R786W	786	Missense	distal	7	no	4.971	4.789	PhosphoSitePlus	CCLE	3.516	Down-regulation
AGC_PDK1_PDPK1_ST	P05106	ITGB3	O15530	PDPK1	T784	I783T	783	Missense	proximal	-1	no	4.331	4.794	EPSD	CCLE	3.516	Up-regulation
AGC_PDK1_PDPK1_ST	P05106	ITGB3	O15530	PDPK1	T784	R786W	786	Missense	proximal	2	no	4.331	4.245	EPSD	CCLE	3.516	Down-regulation
AGC_PDK1_PDPK1_ST	O60331	PIP5K1C	O15530	PDPK1	T69	A65V	65	Missense	distal	-4	no	4.887	4.890	EPSD	CCLE	3.516	Up-regulation
AGC_PDK1_PDPK1_ST	O60331	PIP5K1C	O15530	PDPK1	T70	A65V	65	Missense	distal	-5	no	3.767	3.846	EPSD	CCLE	3.516	Up-regulation
AGC_PDK1_PDPK1_ST	Q9Y243	AKT3	O15530	PDPK1	T447	I446T	446	Missense	proximal	-1	no	4.706	5.170	EPSD	CCLE	3.516	Up-regulation
AGC_PDK1_PDPK1_ST	O00141	SGK1	O15530	PDPK1	S401	D403N	403	Missense	proximal	2	no	3.654	3.705	EPSD	CCLE	3.516	Up-regulation
AGC_PDK1_PDPK1_ST	P36507	MAP2K2	O15530	PDPK1	S295	R299K	299	Missense	distal	4	no	4.451	3.867	EPSD	CCLE	3.516	Down-regulation
AGC_PDK1_PDPK1_ST	P36507	MAP2K2	O15530	PDPK1	T394	R397H	397	Missense	distal	3	no	4.121	4.225	EPSD	CCLE	3.516	Up-regulation
AGC_PDK1_PDPK1_ST	Q13153	PAK1	O15530	PDPK1	S262	E255D	255	Missense	distal	-7	no	3.956	4.045	EPSD	CCLE	3.516	Up-regulation
AGC_PDK1_PDPK1_ST	Q13153	PAK1	O15530	PDPK1	T481	E488K	488	Missense	distal	7	no	5.140	5.099	EPSD	CCLE	3.516	Down-regulation
AGC_PDK1_PDPK1_ST	Q05655	PRKCD	O15530	PDPK1	T507	R504Q	504	Missense	distal	-3	no	9.430	8.695	PhosphoSitePlus	CCLE	3.516	Down-regulation
AGC_PDK1_PDPK1_ST	Q05655	PRKCD	O15530	PDPK1	S626	P627L	627	Missense	proximal	1	no	5.296	2.877	EPSD	CCLE	3.516	Loss
AGC_PDK1_PDPK1_ST	Q99683	MAP3K5	O15530	PDPK1	S83	R78Q	78	Missense	distal	-5	no	5.317	5.297	EPSD	CCLE	3.516	Down-regulation
AGC_PDK1_PDPK1_ST	Q99683	MAP3K5	O15530	PDPK1	S1033	S1029N	1029	Missense	distal	-4	no	4.389	4.372	EPSD	CCLE	3.516	Down-regulation
AGC_PDK1_PDPK1_ST	Q16513	PKN2	O15530	PDPK1	S306	M311V	311	Missense	distal	5	no	6.054	5.621	EPSD	CCLE	3.516	Down-regulation
AGC_PDK1_PDPK1_ST	Q16513	PKN2	O15530	PDPK1	S310	M311V	311	Missense	proximal	1	no	3.792	3.759	EPSD	CCLE	3.516	Down-regulation
AGC_PDK1_PDPK1_ST	Q02156	PRKCE	O15530	PDPK1	T175	N168T	168	Missense	distal	-7	no	4.405	4.636	EPSD	CCLE	3.516	Up-regulation
AGC_PDK1_PDPK1_ST	Q02156	PRKCE	O15530	PDPK1	S329	E328Q	328	Missense	proximal	-1	no	5.133	5.254	EPSD	CCLE	3.516	Up-regulation
AGC_PDK1_PDPK1_ST	Q02156	PRKCE	O15530	PDPK1	S350	I356L	356	Missense	distal	6	no	5.834	5.833	EPSD	CCLE	3.516	Down-regulation
AGC_PDK1_PDPK1_ST	Q02156	PRKCE	O15530	PDPK1	S418	M423V	423	Missense	distal	5	no	4.839	4.406	EPSD	CCLE	3.516	Down-regulation
STE_STE11_ASK_MAP3K5_ST	Q9UER7	DAXX	Q99683	MAP3K5	S53	K56T	56	Missense	distal	3	no	27.342	26.927	EPSD	CCLE	22.468	Down-regulation
STE_STE11_ASK_MAP3K5_ST	Q9UER7	DAXX	Q99683	MAP3K5	S165	T162I	162	Missense	distal	-3	no	24.658	26.310	EPSD	CCLE	22.468	Up-regulation
STE_STE11_ASK_MAP3K5_ST	Q9UER7	DAXX	Q99683	MAP3K5	S682	S683Y	683	Missense	proximal	1	no	19.306	24.634	EPSD	CCLE	22.468	Gain
STE_STE11_ASK_MAP3K5_ST	Q9UER7	DAXX	Q99683	MAP3K5	T684	S683Y	683	Missense	proximal	-1	no	24.662	26.249	EPSD	CCLE	22.468	Up-regulation
STE_STE11_ASK_MAP3K5_ST	P46734	MAP2K3	Q99683	MAP3K5	T39	L44P	44	Missense	distal	5	no	25.039	25.170	EPSD	CCLE	22.468	Up-regulation
STE_STE11_ASK_MAP3K5_ST	P45983	MAPK8	Q99683	MAP3K5	T183	T188N	188	Missense	distal	5	no	46.269	45.599	PhosphoSitePlus;EPSD	CCLE	22.468	Down-regulation
STE_STE11_ASK_MAP3K5_ST	P45983	MAPK8	Q99683	MAP3K5	T183	T188I	188	Missense	distal	5	no	46.269	45.854	PhosphoSitePlus;EPSD	CCLE	22.468	Down-regulation
STE_STE11_ASK_MAP3K5_ST	P52564	MAP2K6	Q99683	MAP3K5	S207	D213H	213	Missense	distal	6	no	42.328	39.631	PhosphoSitePlus	CCLE	22.468	Down-regulation
STE_STE11_ASK_MAP3K5_ST	P52564	MAP2K6	Q99683	MAP3K5	T211	D213H	213	Missense	proximal	2	no	29.569	30.019	EPSD	CCLE	22.468	Up-regulation
STE_STE11_ASK_MAP3K5_ST	Q99683	MAP3K5	Q99683	MAP3K5	T1015	I1013F	1013	Missense	proximal	-2	no	27.659	27.325	EPSD	CCLE	22.468	Down-regulation
STE_STE11_ASK_MAP3K5_ST	Q9Y3F4	STRAP	Q99683	MAP3K5	T175	D170H	170	Missense	distal	-5	no	35.430	34.097	PhosphoSitePlus;EPSD	CCLE	22.468	Down-regulation
STE_STE11_ASK_MAP3K5_ST	Q15691	MAPRE1	Q99683	MAP3K5	T206	E208K	208	Missense	proximal	2	no	41.243	39.414	PhosphoSitePlus;EPSD	CCLE	22.468	Down-regulation
STE_STE11_ASK_MAP3K5_ST	O15530	PDPK1	Q99683	MAP3K5	T33	T31A	31	Missense	proximal	-2	no	28.793	29.103	EPSD	CCLE	22.468	Up-regulation
STE_STE11_ASK_MAP3K5_ST	O15530	PDPK1	Q99683	MAP3K5	S45	P42T	42	Missense	distal	-3	no	24.636	25.103	EPSD	CCLE	22.468	Up-regulation
STE_STE11_ASK_MAP3K5_ST	O15530	PDPK1	Q99683	MAP3K5	T148	E153K	153	Missense	distal	5	no	28.756	28.602	EPSD	CCLE	22.468	Down-regulation
STE_STE11_ASK_MAP3K5_ST	O15530	PDPK1	Q99683	MAP3K5	S344	P340L	340	Missense	distal	-4	no	25.009	22.818	EPSD	CCLE	22.468	Down-regulation
STE_STE11_ASK_MAP3K5_ST	O15530	PDPK1	Q99683	MAP3K5	T346	P340L	340	Missense	distal	-6	no	24.014	24.036	EPSD	CCLE	22.468	Up-regulation
AGC_GRK_GRK_GRK5_ST	P04637	TP53	P34947	GRK5	S33	E28Q	28	Missense	distal	-5	no	3.196	3.417	EPSD	CCLE	1.854	Up-regulation
CMGC_CK2_CSNK2A2_ST	P18887	XRCC1	P19784	CSNK2A2	S410	S410N	410	Missense	central	0	yes	0.001	0.000	EPSD	CCLE	0.001	Loss
CMGC_CK2_CSNK2A2_ST	Q16543	CDC37	P19784	CSNK2A2	S13	S13F	13	Missense	central	0	yes	0.001	0.000	PhosphoSitePlus	CCLE	0.001	Loss
CMGC_CK2_CSNK2A2_ST	Q00613	HSF1	P19784	CSNK2A2	S368	E371K	371	Missense	distal	3	no	0.001	0.000	EPSD	CCLE	0.001	Loss
TKL_LRRK_LRRK2_ST	Q5S007	LRRK2	Q5S007	LRRK2	T424	S423L	423	Missense	proximal	-1	no	17.358	18.438	EPSD;PhosphoSitePlus	CCLE	15.080	Up-regulation
TKL_LRRK_LRRK2_ST	Q5S007	LRRK2	Q5S007	LRRK2	T826	N828I	828	Missense	proximal	2	no	15.693	16.053	EPSD;PhosphoSitePlus	CCLE	15.080	Up-regulation
TKL_LRRK_LRRK2_ST	Q5S007	LRRK2	Q5S007	LRRK2	T833	N828I	828	Missense	distal	-5	no	16.763	16.746	EPSD;PhosphoSitePlus	CCLE	15.080	Down-regulation
TKL_LRRK_LRRK2_ST	Q5S007	LRRK2	Q5S007	LRRK2	S1159	P1153R	1153	Missense	distal	-6	no	15.902	15.361	EPSD	CCLE	15.080	Down-regulation
TKL_LRRK_LRRK2_ST	Q5S007	LRRK2	Q5S007	LRRK2	S1159	K1154I	1154	Missense	distal	-5	no	15.902	15.845	EPSD	CCLE	15.080	Down-regulation
TKL_LRRK_LRRK2_ST	Q5S007	LRRK2	Q5S007	LRRK2	S1159	N1163I	1163	Missense	distal	4	no	15.902	15.616	EPSD	CCLE	15.080	Down-regulation
TKL_LRRK_LRRK2_ST	Q5S007	LRRK2	Q5S007	LRRK2	T1343	S1345I	1345	Missense	proximal	2	no	16.822	17.091	EPSD;PhosphoSitePlus	CCLE	15.080	Up-regulation
TKL_LRRK_LRRK2_ST	Q5S007	LRRK2	Q5S007	LRRK2	S1345	S1345I	1345	Missense	central	0	yes	17.472	0.000	EPSD;PhosphoSitePlus	CCLE	15.080	Loss
TKL_LRRK_LRRK2_ST	Q5S007	LRRK2	Q5S007	LRRK2	T1348	S1345I	1345	Missense	distal	-3	no	17.633	17.557	EPSD;PhosphoSitePlus	CCLE	15.080	Down-regulation
TKL_LRRK_LRRK2_ST	Q5S007	LRRK2	Q5S007	LRRK2	S1457	A1464G	1464	Missense	distal	7	no	16.050	16.102	EPSD;PhosphoSitePlus	CCLE	15.080	Up-regulation
TKL_LRRK_LRRK2_ST	Q5S007	LRRK2	Q5S007	LRRK2	S1467	A1464G	1464	Missense	distal	-3	no	16.764	16.619	EPSD;PhosphoSitePlus	CCLE	15.080	Down-regulation
TKL_LRRK_LRRK2_ST	Q5S007	LRRK2	Q5S007	LRRK2	T1470	A1464G	1464	Missense	distal	-6	no	16.915	16.411	EPSD;PhosphoSitePlus	CCLE	15.080	Down-regulation
TKL_LRRK_LRRK2_ST	Q5S007	LRRK2	Q5S007	LRRK2	T2483	I2489L	2489	Missense	distal	6	no	19.727	19.867	EPSD;PhosphoSitePlus	CCLE	15.080	Up-regulation
TKL_LRRK_LRRK2_ST	P10636	MAPT	Q5S007	LRRK2	T111	G107V	107	Missense	distal	-4	no	17.258	16.519	EPSD	CCLE	15.080	Down-regulation
TKL_LRRK_LRRK2_ST	P10636	MAPT	Q5S007	LRRK2	T403	K405R	405	Missense	proximal	2	no	18.291	18.342	EPSD	CCLE	15.080	Up-regulation
TKL_LRRK_LRRK2_ST	P10636	MAPT	Q5S007	LRRK2	S447	V442I	442	Missense	distal	-5	no	15.455	15.587	EPSD	CCLE	15.080	Up-regulation
TKL_LRRK_LRRK2_ST	P10636	MAPT	Q5S007	LRRK2	S512	R511H	511	Missense	proximal	-1	no	15.999	15.236	EPSD	CCLE	15.080	Down-regulation
TKL_LRRK_LRRK2_ST	P10636	MAPT	Q5S007	LRRK2	S512	G518S	518	Missense	distal	6	no	15.999	15.762	EPSD	CCLE	15.080	Down-regulation
TKL_LRRK_LRRK2_ST	P10636	MAPT	Q5S007	LRRK2	T522	G518S	518	Missense	distal	-4	no	17.917	17.749	EPSD	CCLE	15.080	Down-regulation
TKL_LRRK_LRRK2_ST	P10636	MAPT	Q5S007	LRRK2	T522	R526L	526	Missense	distal	4	no	17.917	17.252	EPSD	CCLE	15.080	Down-regulation
TKL_LRRK_LRRK2_ST	P10636	MAPT	Q5S007	LRRK2	S558	R559H	559	Missense	proximal	1	no	15.228	15.031	EPSD	CCLE	15.080	Loss
TKL_LRRK_LRRK2_ST	P05067	APP	Q5S007	LRRK2	T381	E385K	385	Missense	distal	4	no	16.467	15.971	EPSD	CCLE	15.080	Down-regulation
TKL_LRRK_LRRK2_ST	P05067	APP	Q5S007	LRRK2	T743	D739V	739	Missense	distal	-4	no	16.869	17.118	PhosphoSitePlus	CCLE	15.080	Up-regulation
TKL_LRRK_LRRK2_ST	Q13501	SQSTM1	Q5S007	LRRK2	T138	V136I	136	Missense	proximal	-2	no	15.898	16.392	PhosphoSitePlus	CCLE	15.080	Up-regulation
TKL_LRRK_LRRK2_ST	Q13501	SQSTM1	Q5S007	LRRK2	T164	R161Q	161	Missense	distal	-3	no	17.232	17.142	EPSD	CCLE	15.080	Down-regulation
TKL_LRRK_LRRK2_ST	Q13501	SQSTM1	Q5S007	LRRK2	T164	P171L	171	Missense	distal	7	no	17.232	17.206	EPSD	CCLE	15.080	Down-regulation
TKL_LRRK_LRRK2_ST	Q13501	SQSTM1	Q5S007	LRRK2	S276	K281R	281	Missense	distal	5	no	15.308	15.268	EPSD	CCLE	15.080	Down-regulation
CAMK_CAMKL_QIK_SIK1_ST	Q9Y618	NCOR2	P57059	SIK1	T803	P798L	798	Missense	distal	-5	no	4.972	7.280	EPSD	CCLE	6.412	Gain
CAMK_CAMKL_QIK_SIK1_ST	Q9Y618	NCOR2	P57059	SIK1	S1018	G1016D	1016	Missense	proximal	-2	no	9.929	9.343	EPSD	CCLE	6.412	Down-regulation
CAMK_CAMKL_QIK_SIK1_ST	Q9Y618	NCOR2	P57059	SIK1	S1018	P1015S	1015	Missense	distal	-3	no	9.929	10.119	EPSD	CCLE	6.412	Up-regulation
CAMK_CAMKL_QIK_SIK1_ST	Q9Y618	NCOR2	P57059	SIK1	S1627	L1623M	1623	Missense	distal	-4	no	3.055	6.650	EPSD	CCLE	6.412	Gain
CMGC_MAPK_p38_MAPK14_ST	P49023	PXN	Q16539	MAPK14	S178	S178N	178	Missense	central	0	yes	11.979	0.000	EPSD	CCLE	5.915	Loss
CMGC_MAPK_p38_MAPK14_ST	P49023	PXN	Q16539	MAPK14	S230	V237M	237	Missense	distal	7	no	10.238	10.194	EPSD	CCLE	5.915	Down-regulation
CMGC_MAPK_p38_MAPK14_ST	P49023	PXN	Q16539	MAPK14	S244	E241K	241	Missense	distal	-3	no	9.196	8.803	EPSD	CCLE	5.915	Down-regulation
CMGC_MAPK_p38_MAPK14_ST	P49023	PXN	Q16539	MAPK14	S244	V237M	237	Missense	distal	-7	no	9.196	9.885	EPSD	CCLE	5.915	Up-regulation
CMGC_MAPK_p38_MAPK14_ST	Q13155	AIMP2	Q16539	MAPK14	S130	A129V	129	Missense	proximal	-1	no	11.674	11.830	EPSD	CCLE	5.915	Up-regulation
CMGC_MAPK_p38_MAPK14_ST	Q02078	MEF2A	Q16539	MAPK14	S98	S98N	98	Missense	central	0	yes	10.930	0.000	EPSD;PhosphoSitePlus	CCLE	5.915	Loss
CMGC_MAPK_p38_MAPK14_ST	Q02078	MEF2A	Q16539	MAPK14	S98	C96Y	96	Missense	proximal	-2	no	10.930	12.067	EPSD;PhosphoSitePlus	CCLE	5.915	Up-regulation
CMGC_MAPK_p38_MAPK14_ST	P04150	NR3C1	Q16539	MAPK14	S144	A146F	146	Missense	proximal	2	no	6.120	5.718	EPSD	CCLE	5.915	Loss
CMGC_MAPK_p38_MAPK14_ST	P04150	NR3C1	Q16539	MAPK14	S148	A146F	146	Missense	proximal	-2	no	6.149	5.599	EPSD	CCLE	5.915	Loss
CMGC_MAPK_p38_MAPK14_ST	P04150	NR3C1	Q16539	MAPK14	S395	S394L	394	Missense	proximal	-1	no	9.357	9.635	EPSD	CCLE	5.915	Up-regulation
CMGC_MAPK_p38_MAPK14_ST	P04150	NR3C1	Q16539	MAPK14	S395	G392D	392	Missense	distal	-3	no	9.357	9.306	EPSD	CCLE	5.915	Down-regulation
CMGC_MAPK_p38_MAPK14_ST	P19634	SLC9A1	Q16539	MAPK14	S693	M696L	696	Missense	distal	3	no	10.047	10.083	EPSD	CCLE	5.915	Up-regulation
CMGC_MAPK_p38_MAPK14_ST	P19634	SLC9A1	Q16539	MAPK14	S703	M696L	696	Missense	distal	-7	no	6.509	6.244	EPSD	CCLE	5.915	Down-regulation
CMGC_MAPK_p38_MAPK14_ST	P19634	SLC9A1	Q16539	MAPK14	S771	T769N	769	Missense	proximal	-2	no	6.985	6.530	EPSD	CCLE	5.915	Down-regulation
CMGC_MAPK_p38_MAPK14_ST	Q09472	EP300	Q16539	MAPK14	S89	M95T	95	Missense	distal	6	no	8.000	7.989	EPSD	CCLE	5.915	Down-regulation
CMGC_MAPK_p38_MAPK14_ST	Q09472	EP300	Q16539	MAPK14	S90	M95T	95	Missense	distal	5	no	10.176	10.489	EPSD	CCLE	5.915	Up-regulation
CMGC_MAPK_p38_MAPK14_ST	Q09472	EP300	Q16539	MAPK14	S112	A105T	105	Missense	distal	-7	no	9.094	8.912	EPSD	CCLE	5.915	Down-regulation
CMGC_MAPK_p38_MAPK14_ST	Q09472	EP300	Q16539	MAPK14	S285	V279I	279	Missense	distal	-6	no	11.201	10.936	EPSD	CCLE	5.915	Down-regulation
CMGC_MAPK_p38_MAPK14_ST	Q09472	EP300	Q16539	MAPK14	S285	S281T	281	Missense	distal	-4	no	11.201	11.478	EPSD	CCLE	5.915	Up-regulation
CMGC_MAPK_p38_MAPK14_ST	Q09472	EP300	Q16539	MAPK14	T317	G322V	322	Missense	distal	5	no	9.145	8.743	EPSD	CCLE	5.915	Down-regulation
CMGC_MAPK_p38_MAPK14_ST	Q09472	EP300	Q16539	MAPK14	T885	R883G	883	Missense	proximal	-2	no	9.555	9.305	EPSD	CCLE	5.915	Down-regulation
CMGC_MAPK_p38_MAPK14_ST	Q09472	EP300	Q16539	MAPK14	T885	P888S	888	Missense	distal	3	no	9.555	9.515	EPSD	CCLE	5.915	Down-regulation
CMGC_MAPK_p38_MAPK14_ST	Q09472	EP300	Q16539	MAPK14	T887	R883G	883	Missense	distal	-4	no	9.099	9.086	EPSD	CCLE	5.915	Down-regulation
CMGC_MAPK_p38_MAPK14_ST	Q09472	EP300	Q16539	MAPK14	T887	P888S	888	Missense	proximal	1	no	9.099	1.816	EPSD	CCLE	5.915	Loss
CMGC_MAPK_p38_MAPK14_ST	Q09472	EP300	Q16539	MAPK14	T1724	A1721V	1721	Missense	distal	-3	no	7.140	5.639	EPSD	CCLE	5.915	Loss
CMGC_MAPK_p38_MAPK14_ST	Q09472	EP300	Q16539	MAPK14	S1726	A1721V	1721	Missense	distal	-5	no	9.245	9.737	EPSD	CCLE	5.915	Up-regulation
CMGC_MAPK_p38_MAPK14_ST	Q09472	EP300	Q16539	MAPK14	S1849	P1855L	1855	Missense	distal	6	no	9.238	9.099	EPSD	CCLE	5.915	Down-regulation
CMGC_MAPK_p38_MAPK14_ST	Q09472	EP300	Q16539	MAPK14	T1851	P1855L	1855	Missense	distal	4	no	9.693	9.054	EPSD	CCLE	5.915	Down-regulation
CMGC_MAPK_p38_MAPK14_ST	Q09472	EP300	Q16539	MAPK14	T1854	P1855L	1855	Missense	proximal	1	no	11.552	3.501	EPSD	CCLE	5.915	Loss
CMGC_MAPK_p38_MAPK14_ST	Q09472	EP300	Q16539	MAPK14	T1857	P1855L	1855	Missense	proximal	-2	no	10.922	9.542	EPSD	CCLE	5.915	Down-regulation
CMGC_MAPK_p38_MAPK14_ST	Q09472	EP300	Q16539	MAPK14	T1906	A1902V	1902	Missense	distal	-4	no	9.300	9.582	EPSD	CCLE	5.915	Up-regulation
CMGC_MAPK_p38_MAPK14_ST	Q09472	EP300	Q16539	MAPK14	T1909	A1902V	1902	Missense	distal	-7	no	11.278	10.460	EPSD	CCLE	5.915	Down-regulation
CMGC_MAPK_p38_MAPK14_ST	Q09472	EP300	Q16539	MAPK14	S2309	Q2306E	2306	Missense	distal	-3	no	7.151	7.634	EPSD	CCLE	5.915	Up-regulation
CMGC_MAPK_p38_MAPK14_ST	Q09472	EP300	Q16539	MAPK14	S2309	R2308H	2308	Missense	proximal	-1	no	7.151	7.306	EPSD	CCLE	5.915	Up-regulation
CMGC_MAPK_p38_MAPK14_ST	Q09472	EP300	Q16539	MAPK14	S2315	R2308H	2308	Missense	distal	-7	no	13.154	12.859	EPSD	CCLE	5.915	Down-regulation
CMGC_MAPK_p38_MAPK14_ST	P15336	ATF2	Q16539	MAPK14	T69	R74K	74	Missense	distal	5	no	11.101	10.807	PhosphoSitePlus;EPSD	CCLE	5.915	Down-regulation
CMGC_MAPK_p38_MAPK14_ST	P15336	ATF2	Q16539	MAPK14	T71	R74K	74	Missense	distal	3	no	9.601	9.617	EPSD;PhosphoSitePlus	CCLE	5.915	Up-regulation
CMGC_MAPK_p38_MAPK14_ST	P15336	ATF2	Q16539	MAPK14	S307	S307L	307	Missense	central	0	yes	8.199	0.000	EPSD	CCLE	5.915	Loss
CMGC_MAPK_p38_MAPK14_ST	P15336	ATF2	Q16539	MAPK14	T320	A319D	319	Missense	proximal	-1	no	7.720	7.917	EPSD	CCLE	5.915	Up-regulation
CMGC_MAPK_p38_MAPK14_ST	P15336	ATF2	Q16539	MAPK14	T325	A330G	330	Missense	distal	5	no	9.210	9.593	EPSD	CCLE	5.915	Up-regulation
CMGC_MAPK_p38_MAPK14_ST	P15336	ATF2	Q16539	MAPK14	T325	A319D	319	Missense	distal	-6	no	9.210	9.003	EPSD	CCLE	5.915	Down-regulation
CMGC_MAPK_p38_MAPK14_ST	P15336	ATF2	Q16539	MAPK14	S328	A330G	330	Missense	proximal	2	no	11.961	11.996	EPSD	CCLE	5.915	Up-regulation
CMGC_MAPK_p38_MAPK14_ST	P15336	ATF2	Q16539	MAPK14	T333	A330G	330	Missense	distal	-3	no	10.979	10.454	EPSD	CCLE	5.915	Down-regulation
CMGC_MAPK_p38_MAPK14_ST	P15336	ATF2	Q16539	MAPK14	T336	A330G	330	Missense	distal	-6	no	6.363	6.425	EPSD	CCLE	5.915	Up-regulation
CMGC_MAPK_p38_MAPK14_ST	Q9NRR4	DROSHA	Q16539	MAPK14	T274	R277L	277	Missense	distal	3	no	11.616	11.662	EPSD;PhosphoSitePlus	CCLE	5.915	Up-regulation
CMGC_MAPK_p38_MAPK14_ST	Q9NRR4	DROSHA	Q16539	MAPK14	S807	P808L	808	Missense	proximal	1	no	12.762	4.711	EPSD	CCLE	5.915	Loss
CMGC_MAPK_p38_MAPK14_ST	Q99958	FOXC2	Q16539	MAPK14	S36	G32D	32	Missense	distal	-4	no	9.686	10.182	EPSD	CCLE	5.915	Up-regulation
CMGC_MAPK_p38_MAPK14_ST	Q99958	FOXC2	Q16539	MAPK14	S219	S215I	215	Missense	distal	-4	no	8.063	8.230	EPSD	CCLE	5.915	Up-regulation
CMGC_MAPK_p38_MAPK14_ST	Q99958	FOXC2	Q16539	MAPK14	S240	S246P	246	Missense	distal	6	no	9.958	9.970	EPSD	CCLE	5.915	Up-regulation
CMGC_MAPK_p38_MAPK14_ST	Q99958	FOXC2	Q16539	MAPK14	T247	S246P	246	Missense	proximal	-1	no	13.450	13.543	EPSD	CCLE	5.915	Up-regulation
CMGC_MAPK_p38_MAPK14_ST	Q99958	FOXC2	Q16539	MAPK14	T247	P248S	248	Missense	proximal	1	no	13.450	6.167	EPSD	CCLE	5.915	Down-regulation
CMGC_MAPK_p38_MAPK14_ST	Q99958	FOXC2	Q16539	MAPK14	S251	S246P	246	Missense	distal	-5	no	11.391	11.839	EPSD	CCLE	5.915	Up-regulation
CMGC_MAPK_p38_MAPK14_ST	Q99958	FOXC2	Q16539	MAPK14	S251	P248S	248	Missense	distal	-3	no	11.391	12.154	EPSD	CCLE	5.915	Up-regulation
CMGC_MAPK_p38_MAPK14_ST	Q99958	FOXC2	Q16539	MAPK14	S281	G285E	285	Missense	distal	4	no	9.993	10.725	EPSD	CCLE	5.915	Up-regulation
CMGC_MAPK_p38_MAPK14_ST	Q99958	FOXC2	Q16539	MAPK14	S288	G285E	285	Missense	distal	-3	no	14.673	14.828	EPSD	CCLE	5.915	Up-regulation
CMGC_MAPK_p38_MAPK14_ST	Q99958	FOXC2	Q16539	MAPK14	T484	P480S	480	Missense	distal	-4	no	10.131	10.043	EPSD	CCLE	5.915	Down-regulation
CMGC_MAPK_p38_MAPK14_ST	Q99958	FOXC2	Q16539	MAPK14	T484	P485L	485	Missense	proximal	1	no	10.131	2.080	EPSD	CCLE	5.915	Loss
CMGC_MAPK_p38_MAPK14_ST	P36956	SREBF1	Q16539	MAPK14	S63	P69T	69	Missense	distal	6	no	9.913	9.939	EPSD;PhosphoSitePlus	CCLE	5.915	Up-regulation
CMGC_MAPK_p38_MAPK14_ST	P36956	SREBF1	Q16539	MAPK14	S63	A62V	62	Missense	proximal	-1	no	9.913	10.069	EPSD;PhosphoSitePlus	CCLE	5.915	Up-regulation
CMGC_MAPK_p38_MAPK14_ST	P36956	SREBF1	Q16539	MAPK14	T105	K108Q	108	Missense	distal	3	no	9.499	9.524	EPSD	CCLE	5.915	Up-regulation
CMGC_MAPK_p38_MAPK14_ST	P36956	SREBF1	Q16539	MAPK14	T426	E422D	422	Missense	distal	-4	no	11.359	12.151	EPSD;PhosphoSitePlus	CCLE	5.915	Up-regulation
CMGC_MAPK_p38_MAPK14_ST	P36956	SREBF1	Q16539	MAPK14	S524	S520G	520	Missense	distal	-4	no	9.309	9.307	EPSD	CCLE	5.915	Down-regulation
CMGC_MAPK_p38_MAPK14_ST	P14598	NCF1	Q16539	MAPK14	S348	R354L	354	Missense	distal	6	no	13.932	13.805	PhosphoSitePlus;EPSD	CCLE	5.915	Down-regulation
CMGC_MAPK_p38_MAPK14_ST	Q8WYK2	JDP2	Q16539	MAPK14	T143	R142Q	142	Missense	proximal	-1	no	6.578	6.667	EPSD	CCLE	5.915	Up-regulation
CMGC_MAPK_p38_MAPK14_ST	Q8WYK2	JDP2	Q16539	MAPK14	T148	R142Q	142	Missense	distal	-6	no	10.947	10.277	PhosphoSitePlus	CCLE	5.915	Down-regulation
CMGC_MAPK_p38_MAPK14_ST	Q8WYK2	JDP2	Q16539	MAPK14	S151	E158K	158	Missense	distal	7	no	6.420	5.714	EPSD	CCLE	5.915	Loss
CMGC_MAPK_p38_MAPK14_ST	P78356	PIP4K2B	Q16539	MAPK14	S17	S19R	19	Missense	proximal	2	no	5.926	5.780	EPSD	CCLE	5.915	Loss
CMGC_MAPK_p38_MAPK14_ST	P78536	ADAM17	Q16539	MAPK14	S266	G271C	271	Missense	distal	5	no	7.242	6.317	EPSD	CCLE	5.915	Down-regulation
CMGC_MAPK_p38_MAPK14_ST	Q14721	KCNB1	Q16539	MAPK14	S656	S656I	656	Missense	central	0	yes	9.831	0.000	EPSD	CCLE	5.915	Loss
CMGC_MAPK_p38_MAPK14_ST	Q14721	KCNB1	Q16539	MAPK14	S783	K776R	776	Missense	distal	-7	no	12.078	11.812	EPSD	CCLE	5.915	Down-regulation
CMGC_MAPK_p38_MAPK14_ST	P28324	ELK4	Q16539	MAPK14	S180	P181S	181	Missense	proximal	1	no	10.005	2.721	EPSD	CCLE	5.915	Loss
CMGC_MAPK_p38_MAPK14_ST	P28324	ELK4	Q16539	MAPK14	S180	S180Y	180	Missense	central	0	yes	10.005	0.000	EPSD	CCLE	5.915	Loss
CMGC_MAPK_p38_MAPK14_ST	P28324	ELK4	Q16539	MAPK14	T185	P181S	181	Missense	distal	-4	no	9.966	9.879	EPSD	CCLE	5.915	Down-regulation
CMGC_MAPK_p38_MAPK14_ST	P28324	ELK4	Q16539	MAPK14	T185	S180Y	180	Missense	distal	-5	no	9.966	10.414	EPSD	CCLE	5.915	Up-regulation
CMGC_MAPK_p38_MAPK14_ST	P28324	ELK4	Q16539	MAPK14	T420	S413F	413	Missense	distal	-7	no	13.640	12.894	EPSD	CCLE	5.915	Down-regulation
CMGC_MAPK_p38_MAPK14_ST	P04792	HSPB1	Q16539	MAPK14	S82	S78T	78	Missense	distal	-4	no	7.365	7.642	EPSD	CCLE	5.915	Up-regulation
CMGC_MAPK_p38_MAPK14_ST	P04792	HSPB1	Q16539	MAPK14	S199	A203V	203	Missense	distal	4	no	7.301	6.867	EPSD	CCLE	5.915	Down-regulation
CMGC_MAPK_p38_MAPK14_ST	P03372	ESR1	Q16539	MAPK14	S104	F97S	97	Missense	distal	-7	no	7.848	8.594	EPSD	CCLE	5.915	Up-regulation
CMGC_MAPK_p38_MAPK14_ST	P03372	ESR1	Q16539	MAPK14	S294	M297I	297	Missense	distal	3	no	9.793	9.852	EPSD;PhosphoSitePlus	CCLE	5.915	Up-regulation
CMGC_MAPK_p38_MAPK14_ST	Q9H3D4	TP63	Q16539	MAPK14	S30	F29L	29	Missense	proximal	-1	no	6.858	6.894	EPSD	CCLE	5.915	Up-regulation
CMGC_MAPK_p38_MAPK14_ST	P29353	SHC1	Q16539	MAPK14	T29	P30L	30	Missense	proximal	1	no	11.108	3.057	EPSD	CCLE	5.915	Loss
CMGC_MAPK_p38_MAPK14_ST	P29353	SHC1	Q16539	MAPK14	S36	P30L	30	Missense	distal	-6	no	11.449	10.836	EPSD	CCLE	5.915	Down-regulation
CMGC_MAPK_p38_MAPK14_ST	P29353	SHC1	Q16539	MAPK14	S54	C59Y	59	Missense	distal	5	no	9.645	10.546	PhosphoSitePlus;EPSD	CCLE	5.915	Up-regulation
CMGC_MAPK_p38_MAPK14_ST	P29353	SHC1	Q16539	MAPK14	S139	T145M	145	Missense	distal	6	no	8.842	8.853	EPSD	CCLE	5.915	Up-regulation
CMGC_MAPK_p38_MAPK14_ST	P29353	SHC1	Q16539	MAPK14	S213	R214P	214	Missense	proximal	1	no	4.788	12.723	EPSD	CCLE	5.915	Gain
CMGC_MAPK_p38_MAPK14_ST	P41212	ETV6	Q16539	MAPK14	T4	C8S	8	Missense	distal	4	no	9.364	10.515	EPSD	CCLE	5.915	Up-regulation
CMGC_MAPK_p38_MAPK14_ST	P41212	ETV6	Q16539	MAPK14	T4	I10V	10	Missense	distal	6	no	9.364	9.334	EPSD	CCLE	5.915	Down-regulation
CMGC_MAPK_p38_MAPK14_ST	P41212	ETV6	Q16539	MAPK14	T161	E154Q	154	Missense	distal	-7	no	8.711	8.298	EPSD	CCLE	5.915	Down-regulation
CMGC_MAPK_p38_MAPK14_ST	P41212	ETV6	Q16539	MAPK14	S184	R183G	183	Missense	proximal	-1	no	12.096	12.417	EPSD	CCLE	5.915	Up-regulation
CMGC_MAPK_p38_MAPK14_ST	P19419	ELK1	Q16539	MAPK14	T336	S339L	339	Missense	distal	3	no	12.299	12.373	EPSD	CCLE	5.915	Up-regulation
CMGC_MAPK_p38_MAPK14_ST	P19419	ELK1	Q16539	MAPK14	T353	P358H	358	Missense	distal	5	no	9.167	8.613	EPSD	CCLE	5.915	Down-regulation
CMGC_MAPK_p38_MAPK14_ST	P19419	ELK1	Q16539	MAPK14	T363	T368P	368	Missense	distal	5	no	10.509	10.225	EPSD	CCLE	5.915	Down-regulation
CMGC_MAPK_p38_MAPK14_ST	P19419	ELK1	Q16539	MAPK14	T363	P358H	358	Missense	distal	-5	no	10.509	10.823	EPSD	CCLE	5.915	Up-regulation
CMGC_MAPK_p38_MAPK14_ST	P19419	ELK1	Q16539	MAPK14	T368	T368P	368	Missense	central	0	yes	6.828	0.000	EPSD	CCLE	5.915	Loss
CMGC_MAPK_p38_MAPK14_ST	P19419	ELK1	Q16539	MAPK14	S383	A386V	386	Missense	distal	3	no	11.683	11.711	EPSD;PhosphoSitePlus	CCLE	5.915	Up-regulation
CMGC_MAPK_p38_MAPK14_ST	P19419	ELK1	Q16539	MAPK14	S389	A386V	386	Missense	distal	-3	no	13.211	11.710	PhosphoSitePlus;EPSD	CCLE	5.915	Down-regulation
CMGC_MAPK_p38_MAPK14_ST	O43526	KCNQ2	Q16539	MAPK14	S45	S45F	45	Missense	central	0	yes	6.123	0.000	EPSD	CCLE	5.915	Loss
CMGC_MAPK_p38_MAPK14_ST	O43526	KCNQ2	Q16539	MAPK14	S731	V733A	733	Missense	proximal	2	no	10.477	10.641	EPSD	CCLE	5.915	Up-regulation
CMGC_MAPK_p38_MAPK14_ST	Q9BUB5	MKNK1	Q16539	MAPK14	S437	R443L	443	Missense	distal	6	no	10.642	10.515	EPSD	CCLE	5.915	Down-regulation
CMGC_MAPK_p38_MAPK14_ST	Q9Y6Q9	NCOA3	Q16539	MAPK14	S214	P215L	215	Missense	proximal	1	no	11.788	3.737	EPSD	CCLE	5.915	Loss
CMGC_MAPK_p38_MAPK14_ST	Q9Y6Q9	NCOA3	Q16539	MAPK14	S569	Q565H	565	Missense	distal	-4	no	9.494	9.336	EPSD	CCLE	5.915	Down-regulation
CMGC_MAPK_p38_MAPK14_ST	Q9Y6Q9	NCOA3	Q16539	MAPK14	S776	E780Q	780	Missense	distal	4	no	6.180	4.759	EPSD	CCLE	5.915	Loss
CMGC_MAPK_p38_MAPK14_ST	Q9Y6Q9	NCOA3	Q16539	MAPK14	T914	T910A	910	Missense	distal	-4	no	10.161	9.924	EPSD	CCLE	5.915	Down-regulation
CMGC_MAPK_p38_MAPK14_ST	P53667	LIMK1	Q16539	MAPK14	S310	A312T	312	Missense	proximal	2	no	10.607	10.635	PhosphoSitePlus	CCLE	5.915	Up-regulation
CMGC_MAPK_p38_MAPK14_ST	P53667	LIMK1	Q16539	MAPK14	S313	A312T	312	Missense	proximal	-1	no	5.975	6.031	EPSD	CCLE	5.915	Up-regulation
CMGC_MAPK_p38_MAPK14_ST	Q15672	TWIST1	Q16539	MAPK14	S8	S6C	6	Missense	proximal	-2	no	9.523	8.388	EPSD	CCLE	5.915	Down-regulation
CMGC_MAPK_p38_MAPK14_ST	Q15672	TWIST1	Q16539	MAPK14	S8	D4E	4	Missense	distal	-4	no	9.523	8.731	EPSD	CCLE	5.915	Down-regulation
CMGC_MAPK_p38_MAPK14_ST	Q15672	TWIST1	Q16539	MAPK14	S11	S6C	6	Missense	distal	-5	no	12.442	13.144	EPSD	CCLE	5.915	Up-regulation
CMGC_MAPK_p38_MAPK14_ST	Q15672	TWIST1	Q16539	MAPK14	S11	D4E	4	Missense	distal	-7	no	12.442	13.024	EPSD	CCLE	5.915	Up-regulation
CMGC_MAPK_p38_MAPK14_ST	P49137	MAPKAPK2	Q16539	MAPK14	T25	P19L	19	Missense	distal	-6	no	10.957	10.344	EPSD;PhosphoSitePlus	CCLE	5.915	Down-regulation
CMGC_MAPK_p38_MAPK14_ST	P49137	MAPKAPK2	Q16539	MAPK14	T25	P24R	24	Missense	proximal	-1	no	10.957	10.757	EPSD;PhosphoSitePlus	CCLE	5.915	Down-regulation
CMGC_MAPK_p38_MAPK14_ST	P19525	EIF2AK2	Q16539	MAPK14	S181	Y176H	176	Missense	distal	-5	no	6.762	7.076	EPSD	CCLE	5.915	Up-regulation
CMGC_MAPK_p38_MAPK14_ST	P19525	EIF2AK2	Q16539	MAPK14	S456	S462L	462	Missense	distal	6	no	11.951	11.824	EPSD	CCLE	5.915	Down-regulation
CMGC_MAPK_p38_MAPK14_ST	O75582	RPS6KA5	Q16539	MAPK14	S759	S758G	758	Missense	proximal	-1	no	7.234	7.447	EPSD	CCLE	5.915	Up-regulation
CMGC_MAPK_p38_MAPK14_ST	P21397	MAOA	Q16539	MAPK14	T54	I55M	55	Missense	proximal	1	no	5.800	6.315	EPSD	CCLE	5.915	Gain
CMGC_MAPK_p38_MAPK14_ST	P43403	ZAP70	Q16539	MAPK14	S258	A259P	259	Missense	proximal	1	no	7.695	14.014	EPSD	CCLE	5.915	Up-regulation
CMGC_MAPK_p38_MAPK14_ST	P35236	PTPN7	Q16539	MAPK14	T66	E69K	69	Missense	distal	3	no	13.138	13.186	PhosphoSitePlus;EPSD	CCLE	5.915	Up-regulation
CMGC_MAPK_p38_MAPK14_ST	P35236	PTPN7	Q16539	MAPK14	S93	E99K	99	Missense	distal	6	no	13.290	13.284	EPSD;PhosphoSitePlus	CCLE	5.915	Down-regulation
CMGC_MAPK_p38_MAPK14_ST	P35236	PTPN7	Q16539	MAPK14	S143	G147R	147	Missense	distal	4	no	6.326	5.841	EPSD	CCLE	5.915	Loss
CMGC_MAPK_p38_MAPK14_ST	P27816	MAP4	Q16539	MAPK14	S14	P13L	13	Missense	proximal	-1	no	13.726	13.911	EPSD	CCLE	5.915	Up-regulation
CMGC_MAPK_p38_MAPK14_ST	P27816	MAP4	Q16539	MAPK14	S1145	S1145N	1145	Missense	central	0	yes	7.107	0.000	EPSD	CCLE	5.915	Loss
CMGC_MAPK_p38_MAPK14_ST	Q9H211	CDT1	Q16539	MAPK14	T29	A26P	26	Missense	distal	-3	no	10.638	10.286	EPSD	CCLE	5.915	Down-regulation
CMGC_MAPK_p38_MAPK14_ST	Q9H211	CDT1	Q16539	MAPK14	T29	C27F	27	Missense	proximal	-2	no	10.638	11.049	EPSD	CCLE	5.915	Up-regulation
CMGC_MAPK_p38_MAPK14_ST	Q9H211	CDT1	Q16539	MAPK14	T29	T29P	29	Missense	central	0	yes	10.638	0.000	EPSD	CCLE	5.915	Loss
CMGC_MAPK_p38_MAPK14_ST	Q9H211	CDT1	Q16539	MAPK14	S31	A26P	26	Missense	distal	-5	no	11.583	11.919	EPSD	CCLE	5.915	Up-regulation
CMGC_MAPK_p38_MAPK14_ST	Q9H211	CDT1	Q16539	MAPK14	S31	C27F	27	Missense	distal	-4	no	11.583	11.826	EPSD	CCLE	5.915	Up-regulation
CMGC_MAPK_p38_MAPK14_ST	Q9H211	CDT1	Q16539	MAPK14	S31	T29P	29	Missense	proximal	-2	no	11.583	12.303	EPSD	CCLE	5.915	Up-regulation
CMGC_MAPK_p38_MAPK14_ST	Q9H211	CDT1	Q16539	MAPK14	S42	A43T	43	Missense	proximal	1	no	6.554	5.419	EPSD	CCLE	5.915	Loss
CMGC_MAPK_p38_MAPK14_ST	Q9H211	CDT1	Q16539	MAPK14	S79	S81N	81	Missense	proximal	2	no	13.678	13.422	EPSD	CCLE	5.915	Down-regulation
CMGC_MAPK_p38_MAPK14_ST	Q9H211	CDT1	Q16539	MAPK14	T82	S81N	81	Missense	proximal	-1	no	9.524	9.595	EPSD	CCLE	5.915	Up-regulation
CMGC_MAPK_p38_MAPK14_ST	Q9H211	CDT1	Q16539	MAPK14	T102	G106D	106	Missense	distal	4	no	9.473	8.535	EPSD	CCLE	5.915	Down-regulation
CMGC_MAPK_p38_MAPK14_ST	Q9H211	CDT1	Q16539	MAPK14	T152	A155V	155	Missense	distal	3	no	11.586	11.614	EPSD	CCLE	5.915	Up-regulation
CMGC_MAPK_p38_MAPK14_ST	Q9H211	CDT1	Q16539	MAPK14	S372	M375I	375	Missense	distal	3	no	11.415	11.473	EPSD	CCLE	5.915	Up-regulation
CMGC_MAPK_p38_MAPK14_ST	Q9H211	CDT1	Q16539	MAPK14	S391	P395S	395	Missense	distal	4	no	11.410	11.849	PhosphoSitePlus;EPSD	CCLE	5.915	Up-regulation
CMGC_MAPK_p38_MAPK14_ST	Q9H211	CDT1	Q16539	MAPK14	S394	P395S	395	Missense	proximal	1	no	11.973	4.689	EPSD	CCLE	5.915	Loss
CMGC_MAPK_p38_MAPK14_ST	Q9H211	CDT1	Q16539	MAPK14	T402	P395S	395	Missense	distal	-7	no	11.215	11.303	EPSD;PhosphoSitePlus	CCLE	5.915	Up-regulation
CMGC_MAPK_p38_MAPK14_ST	Q00613	HSF1	Q16539	MAPK14	S244	P243L	243	Missense	proximal	-1	no	16.698	16.884	EPSD	CCLE	5.915	Up-regulation
CMGC_MAPK_p38_MAPK14_ST	Q00613	HSF1	Q16539	MAPK14	S292	R287M	287	Missense	distal	-5	no	11.025	10.959	EPSD	CCLE	5.915	Down-regulation
CMGC_MAPK_p38_MAPK14_ST	Q00613	HSF1	Q16539	MAPK14	T369	E371K	371	Missense	proximal	2	no	12.214	11.900	EPSD	CCLE	5.915	Down-regulation
CMGC_MAPK_p38_MAPK14_ST	Q00613	HSF1	Q16539	MAPK14	S419	V424M	424	Missense	distal	5	no	11.046	11.224	EPSD	CCLE	5.915	Up-regulation
CMGC_MAPK_p38_MAPK14_ST	P04637	TP53	Q16539	MAPK14	S33	E28Q	28	Missense	distal	-5	no	11.723	12.150	EPSD;PhosphoSitePlus	CCLE	5.915	Up-regulation
CMGC_MAPK_p38_MAPK14_ST	Q9UIG0	BAZ1B	Q16539	MAPK14	S329	K335Q	335	Missense	distal	6	no	5.984	5.921	EPSD	CCLE	5.915	Down-regulation
CMGC_MAPK_p38_MAPK14_ST	Q9UIG0	BAZ1B	Q16539	MAPK14	S330	K335Q	335	Missense	distal	5	no	11.853	11.798	EPSD	CCLE	5.915	Down-regulation
CMGC_MAPK_p38_MAPK14_ST	Q9UIG0	BAZ1B	Q16539	MAPK14	S361	K360T	360	Missense	proximal	-1	no	11.743	11.886	EPSD	CCLE	5.915	Up-regulation
CMGC_MAPK_p38_MAPK14_ST	Q15717	ELAVL1	Q16539	MAPK14	S202	A204V	204	Missense	proximal	2	no	7.397	7.233	EPSD	CCLE	5.915	Down-regulation
CMGC_MAPK_p38_MAPK14_ST	Q15717	ELAVL1	Q16539	MAPK14	S221	G224D	224	Missense	distal	3	no	8.107	8.117	EPSD	CCLE	5.915	Up-regulation
CMGC_MAPK_p38_MAPK14_ST	Q9NQU5	PAK6	Q16539	MAPK14	S104	R101C	101	Missense	distal	-3	no	12.483	10.288	EPSD	CCLE	5.915	Down-regulation
CMGC_MAPK_p38_MAPK14_ST	Q9NQU5	PAK6	Q16539	MAPK14	S104	R110W	110	Missense	distal	6	no	12.483	12.220	EPSD	CCLE	5.915	Down-regulation
CMGC_MAPK_p38_MAPK14_ST	Q9NQU5	PAK6	Q16539	MAPK14	S132	S135F	135	Missense	distal	3	no	11.251	11.359	EPSD	CCLE	5.915	Up-regulation
CMGC_MAPK_p38_MAPK14_ST	Q9NQU5	PAK6	Q16539	MAPK14	S135	S135F	135	Missense	central	0	yes	6.300	0.000	EPSD	CCLE	5.915	Loss
CMGC_MAPK_p38_MAPK14_ST	Q9NQU5	PAK6	Q16539	MAPK14	S202	G196C	196	Missense	distal	-6	no	11.366	10.555	EPSD	CCLE	5.915	Down-regulation
CMGC_MAPK_p38_MAPK14_ST	Q9NQU5	PAK6	Q16539	MAPK14	S202	G196D	196	Missense	distal	-6	no	11.366	11.098	EPSD	CCLE	5.915	Down-regulation
CMGC_MAPK_p38_MAPK14_ST	Q9NQU5	PAK6	Q16539	MAPK14	S347	L342F	342	Missense	distal	-5	no	11.402	11.457	EPSD	CCLE	5.915	Up-regulation
CMGC_MAPK_p38_MAPK14_ST	Q9NQU5	PAK6	Q16539	MAPK14	S347	A349V	349	Missense	proximal	2	no	11.402	11.238	EPSD	CCLE	5.915	Down-regulation
CMGC_MAPK_p38_MAPK14_ST	Q9NQU5	PAK6	Q16539	MAPK14	S351	A349V	349	Missense	proximal	-2	no	8.820	8.405	EPSD	CCLE	5.915	Down-regulation
CMGC_MAPK_p38_MAPK14_ST	Q9NQU5	PAK6	Q16539	MAPK14	T354	A349V	349	Missense	distal	-5	no	6.255	6.747	EPSD	CCLE	5.915	Up-regulation
CMGC_MAPK_p38_MAPK14_ST	Q06413	MEF2C	Q16539	MAPK14	S222	G215D	215	Missense	distal	-7	no	11.367	11.004	EPSD	CCLE	5.915	Down-regulation
CMGC_MAPK_p38_MAPK14_ST	Q8NHW3	MAFA	Q16539	MAPK14	T53	P54S	54	Missense	proximal	1	no	9.989	2.706	EPSD	CCLE	5.915	Loss
CMGC_MAPK_p38_MAPK14_ST	Q8NHW3	MAFA	Q16539	MAPK14	T57	P54S	54	Missense	distal	-3	no	9.694	10.458	PhosphoSitePlus;EPSD	CCLE	5.915	Up-regulation
CMGC_MAPK_p38_MAPK14_ST	Q8NHW3	MAFA	Q16539	MAPK14	S65	P66S	66	Missense	proximal	1	no	9.470	2.186	EPSD	CCLE	5.915	Loss
CMGC_MAPK_p38_MAPK14_ST	Q14934	NFATC4	Q16539	MAPK14	S168	S174N	174	Missense	distal	6	no	13.791	13.770	PhosphoSitePlus;EPSD	CCLE	5.915	Down-regulation
CMGC_MAPK_p38_MAPK14_ST	Q14934	NFATC4	Q16539	MAPK14	S170	S174N	174	Missense	distal	4	no	12.606	12.089	EPSD;PhosphoSitePlus	CCLE	5.915	Down-regulation
CMGC_MAPK_p38_MAPK14_ST	Q14934	NFATC4	Q16539	MAPK14	S217	S221F	221	Missense	distal	4	no	10.934	9.360	EPSD	CCLE	5.915	Down-regulation
CMGC_MAPK_p38_MAPK14_ST	Q14934	NFATC4	Q16539	MAPK14	S221	S221F	221	Missense	central	0	yes	9.476	0.000	EPSD	CCLE	5.915	Loss
CMGC_MAPK_p38_MAPK14_ST	Q14934	NFATC4	Q16539	MAPK14	T226	S221F	221	Missense	distal	-5	no	10.758	11.543	EPSD	CCLE	5.915	Up-regulation
CMGC_MAPK_p38_MAPK14_ST	Q14934	NFATC4	Q16539	MAPK14	S592	A590T	590	Missense	proximal	-2	no	12.002	11.945	EPSD	CCLE	5.915	Down-regulation
CMGC_MAPK_p38_MAPK14_ST	Q14934	NFATC4	Q16539	MAPK14	S716	P720L	720	Missense	distal	4	no	11.261	10.621	EPSD	CCLE	5.915	Down-regulation
CMGC_MAPK_p38_MAPK14_ST	Q14934	NFATC4	Q16539	MAPK14	S819	P820L	820	Missense	proximal	1	no	11.591	3.540	EPSD	CCLE	5.915	Loss
CMGC_MAPK_p38_MAPK14_ST	O43524	FOXO3	Q16539	MAPK14	T32	R27G	27	Missense	distal	-5	no	7.301	7.463	EPSD	CCLE	5.915	Up-regulation
CMGC_MAPK_p38_MAPK14_ST	O43524	FOXO3	Q16539	MAPK14	S43	Q41K	41	Missense	proximal	-2	no	11.871	11.595	EPSD	CCLE	5.915	Down-regulation
CMGC_MAPK_p38_MAPK14_ST	O43524	FOXO3	Q16539	MAPK14	S55	E61D	61	Missense	distal	6	no	6.289	6.188	EPSD	CCLE	5.915	Down-regulation
CMGC_MAPK_p38_MAPK14_ST	O43524	FOXO3	Q16539	MAPK14	S446	R444C	444	Missense	proximal	-2	no	7.519	6.584	EPSD	CCLE	5.915	Down-regulation
CMGC_MAPK_p38_MAPK14_ST	O43524	FOXO3	Q16539	MAPK14	S667	P672S	672	Missense	distal	5	no	5.719	6.170	EPSD	CCLE	5.915	Gain
CMGC_MAPK_p38_MAPK14_ST	O43524	FOXO3	Q16539	MAPK14	S669	P672S	672	Missense	distal	3	no	8.191	8.151	EPSD	CCLE	5.915	Down-regulation
CMGC_MAPK_p38_MAPK14_ST	P42566	EPS15	Q16539	MAPK14	S140	N143D	143	Missense	distal	3	no	10.755	10.761	EPSD	CCLE	5.915	Up-regulation
CMGC_MAPK_p38_MAPK14_ST	P42566	EPS15	Q16539	MAPK14	S324	I321T	321	Missense	distal	-3	no	8.909	10.663	EPSD	CCLE	5.915	Up-regulation
CMGC_MAPK_p38_MAPK14_ST	P42566	EPS15	Q16539	MAPK14	S741	S748N	748	Missense	distal	7	no	6.487	6.188	EPSD	CCLE	5.915	Down-regulation
CMGC_MAPK_p38_MAPK14_ST	P42566	EPS15	Q16539	MAPK14	S744	S748N	748	Missense	distal	4	no	7.117	6.600	EPSD	CCLE	5.915	Down-regulation
CMGC_MAPK_p38_MAPK14_ST	P42566	EPS15	Q16539	MAPK14	T777	T777I	777	Missense	central	0	yes	6.319	0.000	EPSD	CCLE	5.915	Loss
CMGC_MAPK_p38_MAPK14_ST	P42566	EPS15	Q16539	MAPK14	S796	S790P	790	Missense	distal	-6	no	9.943	9.337	PhosphoSitePlus	CCLE	5.915	Down-regulation
CMGC_MAPK_p38_MAPK14_ST	O60381	HBP1	Q16539	MAPK14	S402	Q407H	407	Missense	distal	5	no	9.658	9.313	PhosphoSitePlus	CCLE	5.915	Down-regulation
CMGC_MAPK_p38_MAPK14_ST	Q8IW41	MAPKAPK5	Q16539	MAPK14	S212	P213L	213	Missense	proximal	1	no	11.797	3.746	EPSD	CCLE	5.915	Loss
CMGC_MAPK_p38_MAPK14_ST	Q8IW41	MAPKAPK5	Q16539	MAPK14	T214	P213L	213	Missense	proximal	-1	no	9.025	9.211	EPSD	CCLE	5.915	Up-regulation
CMGC_MAPK_p38_MAPK14_ST	Q8IW41	MAPKAPK5	Q16539	MAPK14	T217	P213L	213	Missense	distal	-4	no	6.492	7.004	EPSD	CCLE	5.915	Up-regulation
CMGC_MAPK_p38_MAPK14_ST	P42677	RPS27	Q16539	MAPK14	S27	N29S	29	Missense	proximal	2	no	10.240	10.496	PhosphoSitePlus	CCLE	5.915	Up-regulation
CMGC_MAPK_p38_MAPK14_ST	Q92993	KAT5	Q16539	MAPK14	T77	L83I	83	Missense	distal	6	no	7.401	7.317	EPSD	CCLE	5.915	Down-regulation
CMGC_MAPK_p38_MAPK14_ST	Q92993	KAT5	Q16539	MAPK14	S90	L83I	83	Missense	distal	-7	no	11.728	11.587	EPSD	CCLE	5.915	Down-regulation
CMGC_MAPK_p38_MAPK14_ST	Q92993	KAT5	Q16539	MAPK14	S90	P88S	88	Missense	proximal	-2	no	11.728	11.239	EPSD	CCLE	5.915	Down-regulation
CMGC_MAPK_p38_MAPK14_ST	Q92993	KAT5	Q16539	MAPK14	S90	P88F	88	Missense	proximal	-2	no	11.728	10.515	EPSD	CCLE	5.915	Down-regulation
CMGC_MAPK_p38_MAPK14_ST	Q92993	KAT5	Q16539	MAPK14	S90	P88L	88	Missense	proximal	-2	no	11.728	10.348	EPSD	CCLE	5.915	Down-regulation
CMGC_MAPK_p38_MAPK14_ST	Q92993	KAT5	Q16539	MAPK14	S90	E92Q	92	Missense	proximal	2	no	11.728	11.191	EPSD	CCLE	5.915	Down-regulation
CMGC_MAPK_p38_MAPK14_ST	P41235	HNF4A	Q16539	MAPK14	S313	R312C	312	Missense	proximal	-1	no	7.604	7.867	EPSD	CCLE	5.915	Up-regulation
CMGC_MAPK_p38_MAPK14_ST	P41235	HNF4A	Q16539	MAPK14	S378	E372G	372	Missense	distal	-6	no	11.760	11.450	EPSD	CCLE	5.915	Down-regulation
CMGC_MAPK_p38_MAPK14_ST	P41235	HNF4A	Q16539	MAPK14	S436	G440S	440	Missense	distal	4	no	10.226	10.458	EPSD	CCLE	5.915	Up-regulation
CMGC_MAPK_p38_MAPK14_ST	P05787	KRT8	Q16539	MAPK14	S451	S451F	451	Missense	central	0	yes	7.278	0.000	EPSD	CCLE	5.915	Loss
CMGC_MAPK_p38_MAPK14_ST	O95644	NFATC1	Q16539	MAPK14	S117	R119L	119	Missense	proximal	2	no	13.323	12.979	EPSD	CCLE	5.915	Down-regulation
CMGC_MAPK_p38_MAPK14_ST	O95644	NFATC1	Q16539	MAPK14	S117	T123N	123	Missense	distal	6	no	13.323	13.265	EPSD	CCLE	5.915	Down-regulation
CMGC_MAPK_p38_MAPK14_ST	O95644	NFATC1	Q16539	MAPK14	S172	S176I	176	Missense	distal	4	no	13.182	12.393	PhosphoSitePlus	CCLE	5.915	Down-regulation
CMGC_MAPK_p38_MAPK14_ST	O95644	NFATC1	Q16539	MAPK14	S172	S179P	179	Missense	distal	7	no	13.182	12.960	PhosphoSitePlus	CCLE	5.915	Down-regulation
CMGC_MAPK_p38_MAPK14_ST	O95644	NFATC1	Q16539	MAPK14	S175	S176I	176	Missense	proximal	1	no	6.910	6.515	EPSD	CCLE	5.915	Down-regulation
CMGC_MAPK_p38_MAPK14_ST	O95644	NFATC1	Q16539	MAPK14	S175	S179P	179	Missense	distal	4	no	6.910	6.471	EPSD	CCLE	5.915	Down-regulation
CMGC_MAPK_p38_MAPK14_ST	O95644	NFATC1	Q16539	MAPK14	S175	R180L	180	Missense	distal	5	no	6.910	6.273	EPSD	CCLE	5.915	Down-regulation
CMGC_MAPK_p38_MAPK14_ST	O95644	NFATC1	Q16539	MAPK14	S178	S179P	179	Missense	proximal	1	no	5.489	12.772	EPSD	CCLE	5.915	Gain
CMGC_MAPK_p38_MAPK14_ST	O95644	NFATC1	Q16539	MAPK14	S184	S179P	179	Missense	distal	-5	no	6.285	6.733	EPSD	CCLE	5.915	Up-regulation
CMGC_MAPK_p38_MAPK14_ST	O95644	NFATC1	Q16539	MAPK14	S184	R180L	180	Missense	distal	-4	no	6.285	6.874	EPSD	CCLE	5.915	Up-regulation
CMGC_MAPK_p38_MAPK14_ST	O95644	NFATC1	Q16539	MAPK14	S211	S207F	207	Missense	distal	-4	no	10.863	11.568	EPSD	CCLE	5.915	Up-regulation
CMGC_MAPK_p38_MAPK14_ST	O95644	NFATC1	Q16539	MAPK14	S233	R235Q	235	Missense	proximal	2	no	10.753	10.327	EPSD	CCLE	5.915	Down-regulation
CMGC_MAPK_p38_MAPK14_ST	O95644	NFATC1	Q16539	MAPK14	S237	R235Q	235	Missense	proximal	-2	no	10.127	9.800	EPSD	CCLE	5.915	Down-regulation
CMGC_MAPK_p38_MAPK14_ST	O95644	NFATC1	Q16539	MAPK14	S237	R243C	243	Missense	distal	6	no	10.127	9.852	EPSD	CCLE	5.915	Down-regulation
CMGC_MAPK_p38_MAPK14_ST	O95644	NFATC1	Q16539	MAPK14	S239	R235Q	235	Missense	distal	-4	no	6.025	6.394	EPSD	CCLE	5.915	Up-regulation
CMGC_MAPK_p38_MAPK14_ST	O95644	NFATC1	Q16539	MAPK14	S239	R243C	243	Missense	distal	4	no	6.025	5.591	EPSD	CCLE	5.915	Loss
CMGC_MAPK_p38_MAPK14_ST	O95644	NFATC1	Q16539	MAPK14	S239	S245I	245	Missense	distal	6	no	6.025	5.815	EPSD	CCLE	5.915	Loss
CMGC_MAPK_p38_MAPK14_ST	O95644	NFATC1	Q16539	MAPK14	S241	R235Q	235	Missense	distal	-6	no	13.363	12.693	EPSD	CCLE	5.915	Down-regulation
CMGC_MAPK_p38_MAPK14_ST	O95644	NFATC1	Q16539	MAPK14	S241	R243C	243	Missense	proximal	2	no	13.363	13.095	EPSD	CCLE	5.915	Down-regulation
CMGC_MAPK_p38_MAPK14_ST	O95644	NFATC1	Q16539	MAPK14	S241	S245I	245	Missense	distal	4	no	13.363	12.574	EPSD	CCLE	5.915	Down-regulation
CMGC_MAPK_p38_MAPK14_ST	O95644	NFATC1	Q16539	MAPK14	S250	R243C	243	Missense	distal	-7	no	6.694	6.302	EPSD	CCLE	5.915	Down-regulation
CMGC_MAPK_p38_MAPK14_ST	O95644	NFATC1	Q16539	MAPK14	S250	S245I	245	Missense	distal	-5	no	6.694	7.094	EPSD	CCLE	5.915	Up-regulation
CMGC_MAPK_p38_MAPK14_ST	O95644	NFATC1	Q16539	MAPK14	S261	N264S	264	Missense	distal	3	no	13.340	13.294	EPSD	CCLE	5.915	Down-regulation
CMGC_MAPK_p38_MAPK14_ST	O95644	NFATC1	Q16539	MAPK14	S278	R273W	273	Missense	distal	-5	no	11.081	11.826	EPSD	CCLE	5.915	Up-regulation
CMGC_MAPK_p38_MAPK14_ST	O95644	NFATC1	Q16539	MAPK14	S282	P287S	287	Missense	distal	5	no	12.738	13.188	EPSD	CCLE	5.915	Up-regulation
CMGC_MAPK_p38_MAPK14_ST	O95644	NFATC1	Q16539	MAPK14	T284	P287S	287	Missense	distal	3	no	10.203	10.163	EPSD	CCLE	5.915	Down-regulation
CMGC_MAPK_p38_MAPK14_ST	O95644	NFATC1	Q16539	MAPK14	S286	P287S	287	Missense	proximal	1	no	10.865	3.581	EPSD	CCLE	5.915	Loss
CMGC_MAPK_p38_MAPK14_ST	O95644	NFATC1	Q16539	MAPK14	S290	P287S	287	Missense	distal	-3	no	9.130	9.894	EPSD	CCLE	5.915	Up-regulation
CMGC_MAPK_p38_MAPK14_ST	O95644	NFATC1	Q16539	MAPK14	S359	G358V	358	Missense	proximal	-1	no	6.576	6.579	EPSD	CCLE	5.915	Up-regulation
CMGC_MAPK_p38_MAPK14_ST	O95644	NFATC1	Q16539	MAPK14	S403	Y407C	407	Missense	distal	4	no	12.139	12.034	EPSD	CCLE	5.915	Down-regulation
CMGC_MAPK_p38_MAPK14_ST	O95644	NFATC1	Q16539	MAPK14	S409	Y407C	407	Missense	proximal	-2	no	13.393	12.255	EPSD	CCLE	5.915	Down-regulation
CMGC_MAPK_p38_MAPK14_ST	O95644	NFATC1	Q16539	MAPK14	S670	V672A	672	Missense	proximal	2	no	11.987	12.151	EPSD	CCLE	5.915	Up-regulation
CMGC_MAPK_p38_MAPK14_ST	O95644	NFATC1	Q16539	MAPK14	S670	H673R	673	Missense	distal	3	no	11.987	11.916	EPSD	CCLE	5.915	Down-regulation
CMGC_MAPK_p38_MAPK14_ST	O95644	NFATC1	Q16539	MAPK14	S670	S675G	675	Missense	distal	5	no	11.987	11.731	EPSD	CCLE	5.915	Down-regulation
CMGC_MAPK_p38_MAPK14_ST	O95644	NFATC1	Q16539	MAPK14	S772	T777P	777	Missense	distal	5	no	12.370	12.086	EPSD	CCLE	5.915	Down-regulation
CMGC_MAPK_p38_MAPK14_ST	O95644	NFATC1	Q16539	MAPK14	S782	T777P	777	Missense	distal	-5	no	7.523	7.530	EPSD	CCLE	5.915	Up-regulation
CMGC_MAPK_p38_MAPK14_ST	O95644	NFATC1	Q16539	MAPK14	S903	I909M	909	Missense	distal	6	no	10.463	10.722	EPSD	CCLE	5.915	Up-regulation
CMGC_MAPK_p38_MAPK14_ST	O75676	RPS6KA4	Q16539	MAPK14	S360	S365P	365	Missense	distal	5	no	7.805	7.355	EPSD	CCLE	5.915	Down-regulation
CMGC_MAPK_p38_MAPK14_ST	O75676	RPS6KA4	Q16539	MAPK14	T542	L537M	537	Missense	distal	-5	no	8.890	8.313	EPSD	CCLE	5.915	Down-regulation
CMGC_MAPK_p38_MAPK14_ST	O75676	RPS6KA4	Q16539	MAPK14	T568	L573R	573	Missense	distal	5	no	11.294	11.931	EPSD	CCLE	5.915	Up-regulation
CMGC_MAPK_p38_MAPK14_ST	O75676	RPS6KA4	Q16539	MAPK14	S672	G677S	677	Missense	distal	5	no	6.445	6.700	EPSD	CCLE	5.915	Up-regulation
CMGC_MAPK_p38_MAPK14_ST	O75676	RPS6KA4	Q16539	MAPK14	S672	A679E	679	Missense	distal	7	no	6.445	6.640	EPSD	CCLE	5.915	Up-regulation
CMGC_MAPK_p38_MAPK14_ST	O75676	RPS6KA4	Q16539	MAPK14	S682	G677S	677	Missense	distal	-5	no	12.080	11.699	EPSD	CCLE	5.915	Down-regulation
CMGC_MAPK_p38_MAPK14_ST	O75676	RPS6KA4	Q16539	MAPK14	S682	A679E	679	Missense	distal	-3	no	12.080	11.710	EPSD	CCLE	5.915	Down-regulation
CMGC_MAPK_p38_MAPK14_ST	O75676	RPS6KA4	Q16539	MAPK14	T739	R743W	743	Missense	distal	4	no	6.015	4.740	EPSD	CCLE	5.915	Loss
CMGC_MAPK_p38_MAPK14_ST	O75676	RPS6KA4	Q16539	MAPK14	S745	R743W	743	Missense	proximal	-2	no	12.491	11.965	EPSD	CCLE	5.915	Down-regulation
CMGC_MAPK_p38_MAPK14_ST	P10275	AR	Q16539	MAPK14	S96	Q98R	98	Missense	proximal	2	no	7.133	7.559	EPSD	CCLE	5.915	Up-regulation
CMGC_MAPK_p38_MAPK14_ST	P06400	RB1	Q16539	MAPK14	T373	M379T	379	Missense	distal	6	no	8.453	8.442	EPSD	CCLE	5.915	Down-regulation
CMGC_MAPK_p38_MAPK14_ST	P06400	RB1	Q16539	MAPK14	S608	P609H	609	Missense	proximal	1	no	11.823	-1.831	EPSD	CCLE	5.915	Loss
CMGC_MAPK_p38_MAPK14_ST	P06400	RB1	Q16539	MAPK14	S612	P609H	609	Missense	distal	-3	no	8.447	7.970	EPSD	CCLE	5.915	Down-regulation
CMGC_MAPK_p38_MAPK14_ST	P40763	STAT3	Q16539	MAPK14	T440	H447R	447	Missense	distal	7	no	6.042	6.576	EPSD	CCLE	5.915	Up-regulation
CMGC_MAPK_p38_MAPK14_ST	P10415	BCL2	Q16539	MAPK14	S70	Q73H	73	Missense	distal	3	no	12.013	12.044	EPSD	CCLE	5.915	Up-regulation
CMGC_MAPK_p38_MAPK14_ST	P10415	BCL2	Q16539	MAPK14	T74	Q73H	73	Missense	proximal	-1	no	9.176	9.242	EPSD	CCLE	5.915	Up-regulation
CMGC_MAPK_p38_MAPK14_ST	P10415	BCL2	Q16539	MAPK14	S87	V92L	92	Missense	distal	5	no	11.962	11.672	EPSD;PhosphoSitePlus	CCLE	5.915	Down-regulation
CMGC_MAPK_p38_MAPK14_ST	P10415	BCL2	Q16539	MAPK14	S87	P88R	88	Missense	proximal	1	no	11.962	4.026	EPSD;PhosphoSitePlus	CCLE	5.915	Loss
CMGC_MAPK_p38_MAPK14_ST	P10415	BCL2	Q16539	MAPK14	S87	A82T	82	Missense	distal	-5	no	11.962	12.291	EPSD;PhosphoSitePlus	CCLE	5.915	Up-regulation
CMGC_MAPK_p38_MAPK14_ST	P13473	LAMP2	Q16539	MAPK14	T213	A220T	220	Missense	distal	7	no	12.977	12.634	EPSD;PhosphoSitePlus	CCLE	5.915	Down-regulation
CMGC_MAPK_p38_MAPK14_ST	P55273	CDKN2D	Q16539	MAPK14	S76	G74C	74	Missense	proximal	-2	no	7.827	7.142	EPSD	CCLE	5.915	Down-regulation
CMGC_MAPK_p38_MAPK14_ST	P48436	SOX9	Q16539	MAPK14	S33	G40C	40	Missense	distal	7	no	11.945	11.523	EPSD	CCLE	5.915	Down-regulation
CMGC_MAPK_p38_MAPK14_ST	P48436	SOX9	Q16539	MAPK14	S494	Q496H	496	Missense	proximal	2	no	8.400	8.443	EPSD	CCLE	5.915	Up-regulation
CMGC_MAPK_p38_MAPK14_ST	Q8TE85	GRHL3	Q16539	MAPK14	S215	D210Y	210	Missense	distal	-5	no	9.238	9.063	EPSD	CCLE	5.915	Down-regulation
CMGC_MAPK_p38_MAPK14_ST	Q8TE85	GRHL3	Q16539	MAPK14	S215	P219L	219	Missense	distal	4	no	9.238	8.599	EPSD	CCLE	5.915	Down-regulation
CMGC_MAPK_p38_MAPK14_ST	Q8TE85	GRHL3	Q16539	MAPK14	T454	R447L	447	Missense	distal	-7	no	7.761	7.650	PhosphoSitePlus	CCLE	5.915	Down-regulation
CMGC_MAPK_p38_MAPK14_ST	Q06330	RBPJ	Q16539	MAPK14	S7	P13L	13	Missense	distal	6	no	13.829	13.690	EPSD	CCLE	5.915	Down-regulation
CMGC_MAPK_p38_MAPK14_ST	Q06330	RBPJ	Q16539	MAPK14	S18	P13L	13	Missense	distal	-5	no	9.580	9.861	EPSD	CCLE	5.915	Up-regulation
CMGC_MAPK_p38_MAPK14_ST	Q06330	RBPJ	Q16539	MAPK14	S18	P19A	19	Missense	proximal	1	no	9.580	3.262	EPSD	CCLE	5.915	Loss
CMGC_MAPK_p38_MAPK14_ST	Q07817	BCL2L1	Q16539	MAPK14	T47	E42D	42	Missense	distal	-5	no	5.682	6.556	EPSD	CCLE	5.915	Gain
CMGC_MAPK_p38_MAPK14_ST	Q07817	BCL2L1	Q16539	MAPK14	S62	S62N	62	Missense	central	0	yes	13.524	0.000	PhosphoSitePlus	CCLE	5.915	Loss
CMGC_MAPK_p38_MAPK14_ST	Q02156	PRKCE	Q16539	MAPK14	S329	E328Q	328	Missense	proximal	-1	no	8.746	8.815	EPSD	CCLE	5.915	Up-regulation
CMGC_MAPK_p38_MAPK14_ST	Q02156	PRKCE	Q16539	MAPK14	S350	I356L	356	Missense	distal	6	no	11.179	11.262	PhosphoSitePlus	CCLE	5.915	Up-regulation
CMGC_MAPK_p38_MAPK14_ST	P23769	GATA2	Q16539	MAPK14	S73	P74A	74	Missense	proximal	1	no	8.380	2.062	EPSD	CCLE	5.915	Loss
CMGC_MAPK_p38_MAPK14_ST	P23769	GATA2	Q16539	MAPK14	S192	A198T	198	Missense	distal	6	no	14.920	14.902	PhosphoSitePlus	CCLE	5.915	Down-regulation
CMGC_MAPK_p38_MAPK14_ST	P02511	CRYAB	Q16539	MAPK14	S59	F61I	61	Missense	proximal	2	no	9.297	9.484	PhosphoSitePlus	CCLE	5.915	Up-regulation
CMGC_MAPK_p38_MAPK14_ST	Q15910	EZH2	Q16539	MAPK14	S75	L71M	71	Missense	distal	-4	no	7.697	7.168	EPSD	CCLE	5.915	Down-regulation
CMGC_MAPK_p38_MAPK14_ST	Q15910	EZH2	Q16539	MAPK14	T339	F334C	334	Missense	distal	-5	no	6.862	6.778	EPSD	CCLE	5.915	Down-regulation
CMGC_MAPK_p38_MAPK14_ST	Q01844	EWSR1	Q16539	MAPK14	T79	T75I	75	Missense	distal	-4	no	12.266	12.156	PhosphoSitePlus	CCLE	5.915	Down-regulation
CMGC_MAPK_p38_MAPK14_ST	Q01844	EWSR1	Q16539	MAPK14	T81	T75I	75	Missense	distal	-6	no	7.685	6.662	EPSD	CCLE	5.915	Down-regulation
CMGC_MAPK_p38_MAPK14_ST	Q92945	KHSRP	Q16539	MAPK14	T143	S144L	144	Missense	proximal	1	no	6.478	5.711	EPSD	CCLE	5.915	Loss
CMGC_MAPK_p38_MAPK14_ST	P05198	EIF2S1	Q16539	MAPK14	S91	P92S	92	Missense	proximal	1	no	9.525	2.241	EPSD	CCLE	5.915	Loss
CMGC_MAPK_p38_MAPK14_ST	P05198	EIF2S1	Q16539	MAPK14	S91	K97R	97	Missense	distal	6	no	9.525	9.450	EPSD	CCLE	5.915	Down-regulation
CMGC_MAPK_p38_MAPK14_ST	P05198	EIF2S1	Q16539	MAPK14	S91	C98S	98	Missense	distal	7	no	9.525	10.090	EPSD	CCLE	5.915	Up-regulation
CMGC_MAPK_p38_MAPK14_ST	Q13309	SKP2	Q16539	MAPK14	S179	P173K	173	Missense	distal	-6	no	7.705	7.727	EPSD	CCLE	5.915	Up-regulation
CMGC_MAPK_p38_MAPK14_ST	Q13309	SKP2	Q16539	MAPK14	S179	V183G	183	Missense	distal	4	no	7.705	8.213	EPSD	CCLE	5.915	Up-regulation
CMGC_MAPK_p38_MAPK14_ST	Q13309	SKP2	Q16539	MAPK14	S303	Q298H	298	Missense	distal	-5	no	5.485	6.070	EPSD	CCLE	5.915	Gain
CMGC_MAPK_p38_MAPK14_ST	Q9H3M7	TXNIP	Q16539	MAPK14	S249	C247Y	247	Missense	proximal	-2	no	5.457	6.595	EPSD	CCLE	5.915	Gain
CMGC_MAPK_p38_MAPK14_ST	P18850	ATF6	Q16539	MAPK14	S13	A8G	8	Missense	distal	-5	no	10.641	10.910	EPSD	CCLE	5.915	Up-regulation
CMGC_MAPK_p38_MAPK14_ST	P18850	ATF6	Q16539	MAPK14	T166	K168Q	168	Missense	proximal	2	no	8.902	8.680	PhosphoSitePlus	CCLE	5.915	Down-regulation
Other_NAK_BIKE_AAK1_ST	P49757	NUMB	Q2M2I8	AAK1	T102	D99G	99	Missense	distal	-3	no	11.455	11.388	PhosphoSitePlus	CCLE	2.491	Down-regulation
Other_WNK_WNK4_ST	Q96J92	WNK4	Q96J92	WNK4	S335	R329C	329	Missense	distal	-6	no	3.011	2.836	PhosphoSitePlus	CCLE	2.324	Down-regulation
Other_IKK_CHUK_ST	Q9Y6Q9	NCOA3	O15111	CHUK	S214	P215L	215	Missense	proximal	1	no	199.228	213.301	EPSD	CCLE	187.474	Up-regulation
Other_IKK_CHUK_ST	Q9Y6Q9	NCOA3	O15111	CHUK	S563	Q565H	565	Missense	proximal	2	no	186.024	190.539	EPSD	CCLE	187.474	Gain
Other_IKK_CHUK_ST	Q9Y6Q9	NCOA3	O15111	CHUK	S567	Q565H	565	Missense	proximal	-2	no	195.398	179.529	EPSD	CCLE	187.474	Loss
Other_IKK_CHUK_ST	Q9Y6Q9	NCOA3	O15111	CHUK	S569	Q565H	565	Missense	distal	-4	no	196.837	187.736	EPSD	CCLE	187.474	Down-regulation
Other_IKK_CHUK_ST	Q9Y6Q9	NCOA3	O15111	CHUK	S916	T910A	910	Missense	distal	-6	no	194.919	198.788	EPSD	CCLE	187.474	Up-regulation
Other_IKK_CHUK_ST	P19838	NFKB1	O15111	CHUK	S301	V305I	305	Missense	distal	4	no	190.288	191.692	EPSD	CCLE	187.474	Up-regulation
Other_IKK_CHUK_ST	P19838	NFKB1	O15111	CHUK	S373	G377D	377	Missense	distal	4	no	212.594	216.818	EPSD	CCLE	187.474	Up-regulation
Other_IKK_CHUK_ST	P19838	NFKB1	O15111	CHUK	S373	G379A	379	Missense	distal	6	no	212.594	214.849	EPSD	CCLE	187.474	Up-regulation
Other_IKK_CHUK_ST	P19838	NFKB1	O15111	CHUK	S899	S893N	893	Missense	distal	-6	no	185.834	189.755	EPSD	CCLE	187.474	Gain
Other_IKK_CHUK_ST	P03372	ESR1	O15111	CHUK	S102	F97S	97	Missense	distal	-5	no	176.972	196.159	EPSD	CCLE	187.474	Gain
Other_IKK_CHUK_ST	P03372	ESR1	O15111	CHUK	S236	A239D	239	Missense	distal	3	no	161.705	239.417	EPSD	CCLE	187.474	Gain
Other_IKK_CHUK_ST	Q9Y261	FOXA2	O15111	CHUK	S107	G114E	114	Missense	distal	7	no	239.062	231.340	PhosphoSitePlus;EPSD	CCLE	187.474	Down-regulation
Other_IKK_CHUK_ST	Q9Y261	FOXA2	O15111	CHUK	S107	P108L	108	Missense	proximal	1	no	239.062	253.135	PhosphoSitePlus;EPSD	CCLE	187.474	Up-regulation
Other_IKK_CHUK_ST	Q9Y261	FOXA2	O15111	CHUK	S107	P108S	108	Missense	proximal	1	no	239.062	233.661	PhosphoSitePlus;EPSD	CCLE	187.474	Down-regulation
Other_IKK_CHUK_ST	Q9Y261	FOXA2	O15111	CHUK	S111	G114E	114	Missense	distal	3	no	231.883	213.856	EPSD;PhosphoSitePlus	CCLE	187.474	Down-regulation
Other_IKK_CHUK_ST	Q9Y261	FOXA2	O15111	CHUK	S111	P108L	108	Missense	distal	-3	no	231.883	221.779	EPSD;PhosphoSitePlus	CCLE	187.474	Down-regulation
Other_IKK_CHUK_ST	Q9Y261	FOXA2	O15111	CHUK	S111	P108S	108	Missense	distal	-3	no	231.883	218.015	EPSD;PhosphoSitePlus	CCLE	187.474	Down-regulation
Other_IKK_CHUK_ST	Q9Y261	FOXA2	O15111	CHUK	S338	A336S	336	Missense	proximal	-2	no	210.024	184.369	EPSD	CCLE	187.474	Loss
Other_IKK_CHUK_ST	Q9Y261	FOXA2	O15111	CHUK	S338	E334K	334	Missense	distal	-4	no	210.024	221.789	EPSD	CCLE	187.474	Up-regulation
Other_IKK_CHUK_ST	Q00653	NFKB2	O15111	CHUK	S70	G64V	64	Missense	distal	-6	no	225.266	225.026	EPSD	CCLE	187.474	Down-regulation
Other_IKK_CHUK_ST	Q00653	NFKB2	O15111	CHUK	S812	S814G	814	Missense	proximal	2	no	194.115	198.604	EPSD	CCLE	187.474	Up-regulation
Other_IKK_CHUK_ST	Q00653	NFKB2	O15111	CHUK	S814	S814G	814	Missense	central	0	yes	200.595	0.000	EPSD	CCLE	187.474	Loss
Other_IKK_CHUK_ST	Q00653	NFKB2	O15111	CHUK	S866	D865N	865	Missense	proximal	-1	no	196.741	193.841	EPSD;PhosphoSitePlus	CCLE	187.474	Down-regulation
Other_IKK_CHUK_ST	Q00653	NFKB2	O15111	CHUK	S866	A867V	867	Missense	proximal	1	no	196.741	211.971	EPSD;PhosphoSitePlus	CCLE	187.474	Up-regulation
Other_IKK_CHUK_ST	Q00653	NFKB2	O15111	CHUK	S872	D865N	865	Missense	distal	-7	no	246.284	246.510	PhosphoSitePlus;EPSD	CCLE	187.474	Up-regulation
Other_IKK_CHUK_ST	Q00653	NFKB2	O15111	CHUK	S872	A867V	867	Missense	distal	-5	no	246.284	245.705	PhosphoSitePlus;EPSD	CCLE	187.474	Down-regulation
Other_IKK_CHUK_ST	Q01201	RELB	O15111	CHUK	S116	G112A	112	Missense	distal	-4	no	228.504	222.576	EPSD	CCLE	187.474	Down-regulation
Other_IKK_CHUK_ST	Q01201	RELB	O15111	CHUK	S472	L473P	473	Missense	proximal	1	no	230.199	216.126	PhosphoSitePlus	CCLE	187.474	Down-regulation
Other_IKK_CHUK_ST	Q92793	CREBBP	O15111	CHUK	S2393	G2398R	2398	Missense	distal	5	no	197.504	199.911	EPSD	CCLE	187.474	Up-regulation
Other_IKK_CHUK_ST	Q92793	CREBBP	O15111	CHUK	S2394	G2398R	2398	Missense	distal	4	no	192.098	198.965	EPSD	CCLE	187.474	Up-regulation
Other_IKK_CHUK_ST	P42345	MTOR	O15111	CHUK	S92	G99E	99	Missense	distal	7	no	209.467	201.745	EPSD	CCLE	187.474	Down-regulation
Other_IKK_CHUK_ST	P42345	MTOR	O15111	CHUK	S1982	A1986T	1986	Missense	distal	4	no	195.338	198.025	EPSD	CCLE	187.474	Up-regulation
Other_IKK_CHUK_ST	Q9Y618	NCOR2	O15111	CHUK	S132	R139C	139	Missense	distal	7	no	213.348	211.571	EPSD	CCLE	187.474	Down-regulation
Other_IKK_CHUK_ST	Q9Y618	NCOR2	O15111	CHUK	S745	E749K	749	Missense	distal	4	no	192.899	198.224	EPSD	CCLE	187.474	Up-regulation
Other_IKK_CHUK_ST	Q9Y618	NCOR2	O15111	CHUK	S1210	G1205A	1205	Missense	distal	-5	no	190.548	187.678	EPSD	CCLE	187.474	Down-regulation
Other_IKK_CHUK_ST	Q9Y618	NCOR2	O15111	CHUK	S1261	L1263P	1263	Missense	proximal	2	no	194.808	198.968	EPSD	CCLE	187.474	Up-regulation
Other_IKK_CHUK_ST	Q9Y618	NCOR2	O15111	CHUK	S1270	L1263P	1263	Missense	distal	-7	no	211.065	210.502	EPSD	CCLE	187.474	Down-regulation
Other_IKK_CHUK_ST	Q9Y618	NCOR2	O15111	CHUK	S1627	L1623M	1623	Missense	distal	-4	no	176.229	195.635	EPSD	CCLE	187.474	Gain
Other_IKK_CHUK_ST	Q04206	RELA	O15111	CHUK	S338	S340F	340	Missense	proximal	2	no	202.094	201.847	EPSD	CCLE	187.474	Down-regulation
Other_IKK_CHUK_ST	Q04206	RELA	O15111	CHUK	S529	S535A	535	Missense	distal	6	no	209.821	209.259	EPSD	CCLE	187.474	Down-regulation
Other_IKK_CHUK_ST	Q04206	RELA	O15111	CHUK	S529	L523P	523	Missense	distal	-6	no	209.821	217.730	EPSD	CCLE	187.474	Up-regulation
Other_IKK_CHUK_ST	Q04206	RELA	O15111	CHUK	S536	S535A	535	Missense	proximal	-1	no	262.961	261.313	PhosphoSitePlus	CCLE	187.474	Down-regulation
Other_IKK_CHUK_ST	Q86VP1	TAX1BP1	O15111	CHUK	S3	P8Q	8	Missense	distal	5	no	191.567	186.338	EPSD	CCLE	187.474	Loss
Other_IKK_CHUK_ST	Q86VP1	TAX1BP1	O15111	CHUK	S212	S212R	212	Missense	central	0	yes	210.011	0.000	EPSD	CCLE	187.474	Loss
Other_IKK_CHUK_ST	Q86VP1	TAX1BP1	O15111	CHUK	S345	T349A	349	Missense	distal	4	no	228.914	226.227	EPSD	CCLE	187.474	Down-regulation
Other_IKK_CHUK_ST	Q86VP1	TAX1BP1	O15111	CHUK	S683	R684Q	684	Missense	proximal	1	no	203.413	212.431	EPSD	CCLE	187.474	Up-regulation
Other_IKK_CHUK_ST	Q86VP1	TAX1BP1	O15111	CHUK	S691	R684Q	684	Missense	distal	-7	no	206.607	210.966	EPSD	CCLE	187.474	Up-regulation
Other_IKK_CHUK_ST	Q15717	ELAVL1	O15111	CHUK	S221	G224D	224	Missense	distal	3	no	167.730	195.470	EPSD	CCLE	187.474	Gain
Other_IKK_CHUK_ST	P20749	BCL3	O15111	CHUK	S41	P42L	42	Missense	proximal	1	no	220.483	234.556	EPSD	CCLE	187.474	Up-regulation
Other_IKK_CHUK_ST	P20749	BCL3	O15111	CHUK	S448	G453D	453	Missense	distal	5	no	198.077	198.747	EPSD	CCLE	187.474	Up-regulation
Other_IKK_CHUK_ST	P20749	BCL3	O15111	CHUK	S454	G453D	453	Missense	proximal	-1	no	206.791	210.542	PhosphoSitePlus	CCLE	187.474	Up-regulation
Other_IKK_CHUK_ST	O43524	FOXO3	O15111	CHUK	S55	E61D	61	Missense	distal	6	no	189.599	184.483	EPSD	CCLE	187.474	Loss
Other_IKK_CHUK_ST	O43524	FOXO3	O15111	CHUK	S161	D164N	164	Missense	distal	3	no	192.266	155.305	EPSD	CCLE	187.474	Loss
Other_IKK_CHUK_ST	O43524	FOXO3	O15111	CHUK	S666	P672S	672	Missense	distal	6	no	208.886	200.085	EPSD	CCLE	187.474	Down-regulation
Other_IKK_CHUK_ST	O43524	FOXO3	O15111	CHUK	S667	P672S	672	Missense	distal	5	no	191.044	185.682	EPSD	CCLE	187.474	Loss
Other_IKK_CHUK_ST	O43524	FOXO3	O15111	CHUK	S669	P672S	672	Missense	distal	3	no	222.725	221.149	EPSD	CCLE	187.474	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	O95295	SNAPIN	P24941	CDK2	T14	V9E	9	Missense	distal	-5	no	13.135	13.142	EPSD	CCLE	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	O95295	SNAPIN	P24941	CDK2	S126	R119H	119	Missense	distal	-7	no	8.303	8.083	EPSD	CCLE	8.148	Loss
CMGC_CDK_CDK2_CDK2_ST	Q99638	RAD9A	P24941	CDK2	T292	Q286R	286	Missense	distal	-6	no	12.997	12.996	EPSD	CCLE	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	Q8IZL8	PELP1	P24941	CDK2	T647	P654T	654	Missense	distal	7	no	11.719	11.415	EPSD	CCLE	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	Q8IZL8	PELP1	P24941	CDK2	T647	P653R	653	Missense	distal	6	no	11.719	11.703	EPSD	CCLE	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	Q8IZL8	PELP1	P24941	CDK2	S658	P664S	664	Missense	distal	6	no	16.159	16.160	EPSD	CCLE	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	Q8IZL8	PELP1	P24941	CDK2	S658	P654T	654	Missense	distal	-4	no	16.159	16.326	EPSD	CCLE	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	Q8IZL8	PELP1	P24941	CDK2	S658	P653R	653	Missense	distal	-5	no	16.159	16.206	EPSD	CCLE	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	Q8IZL8	PELP1	P24941	CDK2	T745	P752Q	752	Missense	distal	7	no	14.244	14.090	EPSD	CCLE	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	Q8IZL8	PELP1	P24941	CDK2	T745	I750M	750	Missense	distal	5	no	14.244	14.459	EPSD	CCLE	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	Q8IZL8	PELP1	P24941	CDK2	S1043	E1042K	1042	Missense	proximal	-1	no	14.169	13.284	EPSD	CCLE	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	Q07820	MCL1	P24941	CDK2	T70	R74L	74	Missense	distal	4	no	12.831	13.063	EPSD;PhosphoSitePlus	CCLE	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	Q07820	MCL1	P24941	CDK2	T70	R74Q	74	Missense	distal	4	no	12.831	13.012	EPSD;PhosphoSitePlus	CCLE	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	Q07820	MCL1	P24941	CDK2	T70	S73P	73	Missense	distal	3	no	12.831	12.797	EPSD;PhosphoSitePlus	CCLE	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	Q07820	MCL1	P24941	CDK2	S73	R74Q	74	Missense	proximal	1	no	7.049	8.935	EPSD	CCLE	8.148	Gain
CMGC_CDK_CDK2_CDK2_ST	Q07820	MCL1	P24941	CDK2	T92	D88N	88	Missense	distal	-4	no	17.383	16.995	PhosphoSitePlus;EPSD	CCLE	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	Q07820	MCL1	P24941	CDK2	T163	T156R	156	Missense	distal	-7	no	13.606	13.953	EPSD;PhosphoSitePlus	CCLE	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	Q08999	RBL2	P24941	CDK2	S40	D33N	33	Missense	distal	-7	no	15.777	15.455	EPSD	CCLE	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	Q08999	RBL2	P24941	CDK2	S40	P43L	43	Missense	distal	3	no	15.777	15.394	EPSD	CCLE	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	Q08999	RBL2	P24941	CDK2	T42	P43L	43	Missense	proximal	1	no	16.099	6.278	EPSD	CCLE	8.148	Loss
CMGC_CDK_CDK2_CDK2_ST	Q08999	RBL2	P24941	CDK2	S639	I634L	634	Missense	distal	-5	no	15.320	15.292	PhosphoSitePlus;EPSD	CCLE	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	Q08999	RBL2	P24941	CDK2	S662	T665A	665	Missense	distal	3	no	15.758	15.361	EPSD;PhosphoSitePlus	CCLE	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	Q08999	RBL2	P24941	CDK2	S672	T665A	665	Missense	distal	-7	no	15.811	15.978	EPSD	CCLE	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	Q08999	RBL2	P24941	CDK2	S1080	F1077C	1077	Missense	distal	-3	no	17.587	17.503	EPSD;PhosphoSitePlus	CCLE	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	P10636	MAPT	P24941	CDK2	T69	A66V	66	Missense	distal	-3	no	13.645	13.846	EPSD	CCLE	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	P10636	MAPT	P24941	CDK2	T111	G107V	107	Missense	distal	-4	no	13.764	14.033	EPSD	CCLE	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	P10636	MAPT	P24941	CDK2	T173	P170F	170	Missense	distal	-3	no	9.577	9.764	EPSD	CCLE	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	P10636	MAPT	P24941	CDK2	T173	G174A	174	Missense	proximal	1	no	9.577	2.486	EPSD	CCLE	8.148	Loss
CMGC_CDK_CDK2_CDK2_ST	P10636	MAPT	P24941	CDK2	S228	D221Y	221	Missense	distal	-7	no	9.983	9.868	EPSD	CCLE	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	P10636	MAPT	P24941	CDK2	S228	P234S	234	Missense	distal	6	no	9.983	9.985	EPSD	CCLE	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	P10636	MAPT	P24941	CDK2	S232	P234S	234	Missense	proximal	2	no	15.341	15.408	EPSD	CCLE	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	P10636	MAPT	P24941	CDK2	S238	P234S	234	Missense	distal	-4	no	14.454	14.808	EPSD	CCLE	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	P10636	MAPT	P24941	CDK2	S238	D242H	242	Missense	distal	4	no	14.454	14.281	EPSD	CCLE	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	P10636	MAPT	P24941	CDK2	S411	K405R	405	Missense	distal	-6	no	12.787	12.790	EPSD	CCLE	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	P10636	MAPT	P24941	CDK2	S438	V442I	442	Missense	distal	4	no	13.556	13.301	EPSD	CCLE	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	P10636	MAPT	P24941	CDK2	S516	G518S	518	Missense	proximal	2	no	12.476	12.425	EPSD	CCLE	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	P10636	MAPT	P24941	CDK2	S519	G518S	518	Missense	proximal	-1	no	16.829	15.309	EPSD	CCLE	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	P10636	MAPT	P24941	CDK2	S519	R526L	526	Missense	distal	7	no	16.829	16.369	EPSD	CCLE	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	P10636	MAPT	P24941	CDK2	T522	G518S	518	Missense	distal	-4	no	12.687	13.359	EPSD	CCLE	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	P10636	MAPT	P24941	CDK2	T522	R526L	526	Missense	distal	4	no	12.687	12.919	EPSD	CCLE	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	P10636	MAPT	P24941	CDK2	T529	R526L	526	Missense	distal	-3	no	13.229	12.969	EPSD	CCLE	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	P10636	MAPT	P24941	CDK2	S552	R559H	559	Missense	distal	7	no	15.497	15.139	EPSD	CCLE	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	P10636	MAPT	P24941	CDK2	S713	G706V	706	Missense	distal	-7	no	13.446	13.141	EPSD	CCLE	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	P10636	MAPT	P24941	CDK2	S713	S717C	717	Missense	distal	4	no	13.446	12.685	EPSD	CCLE	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	P10636	MAPT	P24941	CDK2	S721	S717C	717	Missense	distal	-4	no	17.338	16.232	EPSD	CCLE	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	P10636	MAPT	P24941	CDK2	S721	S721C	721	Missense	central	0	yes	17.338	0.000	EPSD	CCLE	8.148	Loss
CMGC_CDK_CDK2_CDK2_ST	P10636	MAPT	P24941	CDK2	S721	H724R	724	Missense	distal	3	no	17.338	18.035	EPSD	CCLE	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	P10636	MAPT	P24941	CDK2	S739	Q741K	741	Missense	proximal	2	no	16.401	16.200	EPSD	CCLE	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	Q99728	BARD1	P24941	CDK2	S251	Q245H	245	Missense	distal	-6	no	15.213	15.214	PhosphoSitePlus;EPSD	CCLE	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	Q99728	BARD1	P24941	CDK2	S330	P331S	331	Missense	proximal	1	no	15.952	4.686	EPSD	CCLE	8.148	Loss
CMGC_CDK_CDK2_CDK2_ST	Q99728	BARD1	P24941	CDK2	S496	Q493H	493	Missense	distal	-3	no	13.404	13.492	EPSD	CCLE	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	O43303	CCP110	P24941	CDK2	S516	A509T	509	Missense	distal	-7	no	12.127	11.960	EPSD;PhosphoSitePlus	CCLE	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	O43303	CCP110	P24941	CDK2	S516	F519V	519	Missense	distal	3	no	12.127	12.777	EPSD;PhosphoSitePlus	CCLE	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	O43303	CCP110	P24941	CDK2	S788	A783G	783	Missense	distal	-5	no	8.763	8.817	EPSD	CCLE	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	Q15648	MED1	P24941	CDK2	S1453	T1457P	1457	Missense	distal	4	no	14.352	14.070	EPSD	CCLE	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	Q15648	MED1	P24941	CDK2	T1457	T1457P	1457	Missense	central	0	yes	12.822	0.000	EPSD	CCLE	8.148	Loss
CMGC_CDK_CDK2_CDK2_ST	P62324	BTG1	P24941	CDK2	S159	N165S	165	Missense	distal	6	no	16.830	16.828	PhosphoSitePlus	CCLE	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	P19338	NCL	P24941	CDK2	S67	V72I	72	Missense	distal	5	no	16.712	16.838	EPSD	CCLE	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	P19338	NCL	P24941	CDK2	T76	V72I	72	Missense	distal	-4	no	14.850	14.747	EPSD;PhosphoSitePlus	CCLE	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	P13639	EEF2	P24941	CDK2	S325	S325C	325	Missense	central	0	yes	9.540	0.000	EPSD	CCLE	8.148	Loss
CMGC_CDK_CDK2_CDK2_ST	P13639	EEF2	P24941	CDK2	S360	P361H	361	Missense	proximal	1	no	13.618	6.859	EPSD	CCLE	8.148	Loss
CMGC_CDK_CDK2_CDK2_ST	P13639	EEF2	P24941	CDK2	S595	C591Y	591	Missense	distal	-4	no	16.187	17.404	EPSD;PhosphoSitePlus	CCLE	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	Q9NYV6	RRN3	P24941	CDK2	S44	P45H	45	Missense	proximal	1	no	15.360	8.601	PhosphoSitePlus	CCLE	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	Q9NYV6	RRN3	P24941	CDK2	T200	P206S	206	Missense	distal	6	no	13.090	13.092	EPSD	CCLE	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	Q9NYV6	RRN3	P24941	CDK2	T200	P201L	201	Missense	proximal	1	no	13.090	3.270	EPSD	CCLE	8.148	Loss
CMGC_CDK_CDK2_CDK2_ST	Q9NYV6	RRN3	P24941	CDK2	T200	A194T	194	Missense	distal	-6	no	13.090	13.091	EPSD	CCLE	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	Q9H211	CDT1	P24941	CDK2	T29	A26P	26	Missense	distal	-3	no	12.530	12.588	PhosphoSitePlus;EPSD	CCLE	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	Q9H211	CDT1	P24941	CDK2	T29	C27F	27	Missense	proximal	-2	no	12.530	12.478	PhosphoSitePlus;EPSD	CCLE	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	Q9H211	CDT1	P24941	CDK2	T29	T29P	29	Missense	central	0	yes	12.530	0.000	PhosphoSitePlus;EPSD	CCLE	8.148	Loss
CMGC_CDK_CDK2_CDK2_ST	Q9H211	CDT1	P24941	CDK2	S31	A26P	26	Missense	distal	-5	no	16.937	16.912	EPSD;PhosphoSitePlus	CCLE	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	Q9H211	CDT1	P24941	CDK2	S31	C27F	27	Missense	distal	-4	no	16.937	17.081	EPSD;PhosphoSitePlus	CCLE	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	Q9H211	CDT1	P24941	CDK2	S31	T29P	29	Missense	proximal	-2	no	16.937	16.970	EPSD;PhosphoSitePlus	CCLE	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	Q9H211	CDT1	P24941	CDK2	S45	A43T	43	Missense	proximal	-2	no	10.206	10.156	EPSD	CCLE	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	Q9H211	CDT1	P24941	CDK2	S79	S81N	81	Missense	proximal	2	no	12.445	12.308	EPSD	CCLE	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	Q9H211	CDT1	P24941	CDK2	T82	S81N	81	Missense	proximal	-1	no	13.985	14.383	EPSD	CCLE	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	Q9H211	CDT1	P24941	CDK2	T102	G106D	106	Missense	distal	4	no	11.500	11.555	EPSD	CCLE	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	Q9H211	CDT1	P24941	CDK2	T152	A155V	155	Missense	distal	3	no	11.611	12.731	EPSD	CCLE	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	Q9H211	CDT1	P24941	CDK2	S372	M375I	375	Missense	distal	3	no	14.541	14.113	EPSD	CCLE	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	Q9H211	CDT1	P24941	CDK2	S391	P395S	395	Missense	distal	4	no	13.572	13.586	EPSD	CCLE	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	Q9H211	CDT1	P24941	CDK2	S394	P395S	395	Missense	proximal	1	no	15.927	4.661	EPSD	CCLE	8.148	Loss
CMGC_CDK_CDK2_CDK2_ST	Q9H211	CDT1	P24941	CDK2	T402	P395S	395	Missense	distal	-7	no	14.160	13.980	EPSD	CCLE	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	P25205	MCM3	P24941	CDK2	S112	R114W	114	Missense	proximal	2	no	14.449	14.546	EPSD	CCLE	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	O75179	ANKRD17	P24941	CDK2	S19	V26G	26	Missense	distal	7	no	14.227	14.638	EPSD	CCLE	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	O75179	ANKRD17	P24941	CDK2	S50	R52H	52	Missense	proximal	2	no	10.411	10.330	EPSD	CCLE	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	O75179	ANKRD17	P24941	CDK2	S50	R52S	52	Missense	proximal	2	no	10.411	10.318	EPSD	CCLE	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	O75179	ANKRD17	P24941	CDK2	S469	A464T	464	Missense	distal	-5	no	17.970	17.944	EPSD	CCLE	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	O75179	ANKRD17	P24941	CDK2	S792	V795I	795	Missense	distal	3	no	8.474	7.197	EPSD	CCLE	8.148	Loss
CMGC_CDK_CDK2_CDK2_ST	O75179	ANKRD17	P24941	CDK2	T1213	S1215R	1215	Missense	proximal	2	no	9.930	10.022	EPSD	CCLE	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	O75179	ANKRD17	P24941	CDK2	S1220	A1226D	1226	Missense	distal	6	no	13.395	13.384	EPSD	CCLE	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	O75179	ANKRD17	P24941	CDK2	S1220	S1215R	1215	Missense	distal	-5	no	13.395	13.486	EPSD	CCLE	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	O75179	ANKRD17	P24941	CDK2	T1577	I1576M	1576	Missense	proximal	-1	no	12.062	13.129	EPSD	CCLE	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	O75179	ANKRD17	P24941	CDK2	S2042	E2036Q	2036	Missense	distal	-6	no	13.105	13.106	EPSD;PhosphoSitePlus	CCLE	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	O75179	ANKRD17	P24941	CDK2	S2081	S2081R	2081	Missense	central	0	yes	14.526	0.000	EPSD	CCLE	8.148	Loss
CMGC_CDK_CDK2_CDK2_ST	O75179	ANKRD17	P24941	CDK2	S2373	S2373Y	2373	Missense	central	0	yes	12.223	0.000	EPSD	CCLE	8.148	Loss
CMGC_CDK_CDK2_CDK2_ST	O75179	ANKRD17	P24941	CDK2	T2379	N2386D	2386	Missense	distal	7	no	11.366	12.146	EPSD	CCLE	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	O75179	ANKRD17	P24941	CDK2	T2379	S2373Y	2373	Missense	distal	-6	no	11.366	11.367	EPSD	CCLE	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	O75179	ANKRD17	P24941	CDK2	S2401	R2398C	2398	Missense	distal	-3	no	15.616	15.530	PhosphoSitePlus;EPSD	CCLE	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	O75179	ANKRD17	P24941	CDK2	T2509	R2502P	2502	Missense	distal	-7	no	14.493	14.149	EPSD	CCLE	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	O14757	CHEK1	P24941	CDK2	S286	T279A	279	Missense	distal	-7	no	12.386	12.553	PhosphoSitePlus;EPSD	CCLE	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	O14757	CHEK1	P24941	CDK2	T362	Q358R	358	Missense	distal	-4	no	11.394	11.370	EPSD	CCLE	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	Q14202	ZMYM3	P24941	CDK2	T62	A64S	64	Missense	proximal	2	no	15.713	15.755	EPSD	CCLE	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	Q14202	ZMYM3	P24941	CDK2	S172	I165T	165	Missense	distal	-7	no	13.701	13.504	EPSD	CCLE	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	Q14202	ZMYM3	P24941	CDK2	S186	P180S	180	Missense	distal	-6	no	13.368	13.367	EPSD	CCLE	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	Q14202	ZMYM3	P24941	CDK2	S214	T208A	208	Missense	distal	-6	no	11.689	11.688	EPSD	CCLE	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	Q14202	ZMYM3	P24941	CDK2	T316	T316I	316	Missense	central	0	yes	16.088	0.000	EPSD	CCLE	8.148	Loss
CMGC_CDK_CDK2_CDK2_ST	Q14202	ZMYM3	P24941	CDK2	T316	R315W	315	Missense	proximal	-1	no	16.088	16.643	EPSD	CCLE	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	Q14202	ZMYM3	P24941	CDK2	S774	P775S	775	Missense	proximal	1	no	12.518	1.252	EPSD	CCLE	8.148	Loss
CMGC_CDK_CDK2_CDK2_ST	Q14202	ZMYM3	P24941	CDK2	T781	P775S	775	Missense	distal	-6	no	14.713	14.712	EPSD	CCLE	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	Q14202	ZMYM3	P24941	CDK2	T817	P813T	813	Missense	distal	-4	no	14.358	14.525	EPSD	CCLE	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	P15336	ATF2	P24941	CDK2	T69	R74K	74	Missense	distal	5	no	14.316	14.155	EPSD	CCLE	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	P15336	ATF2	P24941	CDK2	T71	R74K	74	Missense	distal	3	no	14.670	15.659	EPSD	CCLE	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	P15336	ATF2	P24941	CDK2	T325	A330G	330	Missense	distal	5	no	13.346	13.463	EPSD	CCLE	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	P15336	ATF2	P24941	CDK2	S328	A330G	330	Missense	proximal	2	no	12.868	12.961	EPSD	CCLE	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	P15336	ATF2	P24941	CDK2	T333	A330G	330	Missense	distal	-3	no	11.689	11.851	EPSD	CCLE	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	Q9UKM9	RALY	P24941	CDK2	S110	I108M	108	Missense	proximal	-2	no	9.479	7.549	EPSD	CCLE	8.148	Loss
CMGC_CDK_CDK2_CDK2_ST	Q8WYH8	ING5	P24941	CDK2	T55	L56P	56	Missense	proximal	1	no	3.989	13.810	EPSD	CCLE	8.148	Gain
CMGC_CDK_CDK2_CDK2_ST	Q8WYH8	ING5	P24941	CDK2	S57	L56P	56	Missense	proximal	-1	no	12.411	12.591	EPSD	CCLE	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	Q99607	ELF4	P24941	CDK2	S641	S648P	648	Missense	distal	7	no	16.080	16.232	EPSD	CCLE	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	Q99607	ELF4	P24941	CDK2	T643	S648P	648	Missense	distal	5	no	16.397	16.498	PhosphoSitePlus;EPSD	CCLE	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	Q99607	ELF4	P24941	CDK2	S648	S648P	648	Missense	central	0	yes	14.494	0.000	EPSD;PhosphoSitePlus	CCLE	8.148	Loss
CMGC_CDK_CDK2_CDK2_ST	P50570	DNM2	P24941	CDK2	S762	S761T	761	Missense	proximal	-1	no	8.494	8.702	EPSD	CCLE	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	P50570	DNM2	P24941	CDK2	S764	S761T	761	Missense	distal	-3	no	14.419	14.284	PhosphoSitePlus	CCLE	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	P50570	DNM2	P24941	CDK2	T766	S761T	761	Missense	distal	-5	no	13.426	13.470	EPSD	CCLE	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	Q05209	PTPN12	P24941	CDK2	S323	S324P	324	Missense	proximal	1	no	0.018	11.284	EPSD	CCLE	8.148	Gain
CMGC_CDK_CDK2_CDK2_ST	Q05209	PTPN12	P24941	CDK2	S588	T587P	587	Missense	proximal	-1	no	13.554	13.817	EPSD	CCLE	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	Q05209	PTPN12	P24941	CDK2	T593	T587P	587	Missense	distal	-6	no	11.681	11.682	EPSD	CCLE	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	Q05209	PTPN12	P24941	CDK2	T593	N599H	599	Missense	distal	6	no	11.681	11.673	EPSD	CCLE	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	Q05209	PTPN12	P24941	CDK2	S641	T635I	635	Missense	distal	-6	no	9.087	9.089	EPSD	CCLE	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	Q15788	NCOA1	P24941	CDK2	S372	H368D	368	Missense	distal	-4	no	8.365	9.495	EPSD	CCLE	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	Q15788	NCOA1	P24941	CDK2	S372	T377N	377	Missense	distal	5	no	8.365	8.493	EPSD	CCLE	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	Q15788	NCOA1	P24941	CDK2	S372	T377S	377	Missense	distal	5	no	8.365	8.289	EPSD	CCLE	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	Q15788	NCOA1	P24941	CDK2	S488	Q492L	492	Missense	distal	4	no	16.287	16.338	EPSD;PhosphoSitePlus	CCLE	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	Q15788	NCOA1	P24941	CDK2	S558	S555C	555	Missense	distal	-3	no	10.355	10.363	EPSD	CCLE	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	Q15788	NCOA1	P24941	CDK2	T763	E757A	757	Missense	distal	-6	no	12.212	12.208	EPSD	CCLE	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	P23771	GATA3	P24941	CDK2	S110	G104S	104	Missense	distal	-6	no	11.995	11.991	EPSD	CCLE	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	P23771	GATA3	P24941	CDK2	S110	S110P	110	Missense	central	0	yes	11.995	0.000	EPSD	CCLE	8.148	Loss
CMGC_CDK_CDK2_CDK2_ST	P23771	GATA3	P24941	CDK2	S115	S110P	110	Missense	distal	-5	no	12.062	12.106	EPSD	CCLE	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	Q15554	TERF2	P24941	CDK2	S53	S50N	50	Missense	distal	-3	no	9.258	9.183	EPSD	CCLE	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	Q15554	TERF2	P24941	CDK2	T169	L168P	168	Missense	proximal	-1	no	12.341	12.521	EPSD	CCLE	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	Q9UGP5	POLL	P24941	CDK2	T553	T553A	553	Missense	central	0	yes	15.305	0.000	EPSD;PhosphoSitePlus	CCLE	8.148	Loss
CMGC_CDK_CDK2_CDK2_ST	Q9NSV4	DIAPH3	P24941	CDK2	S48	P50H	50	Missense	proximal	2	no	8.475	8.552	EPSD	CCLE	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	Q9NSV4	DIAPH3	P24941	CDK2	S624	G617R	617	Missense	distal	-7	no	14.198	14.218	EPSD	CCLE	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	Q9NSV4	DIAPH3	P24941	CDK2	S1093	P1099S	1099	Missense	distal	6	no	14.173	14.175	EPSD	CCLE	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	Q9NSV4	DIAPH3	P24941	CDK2	S1096	P1099S	1099	Missense	distal	3	no	10.135	10.169	EPSD	CCLE	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	P28324	ELK4	P24941	CDK2	S180	P181S	181	Missense	proximal	1	no	12.829	1.563	EPSD	CCLE	8.148	Loss
CMGC_CDK_CDK2_CDK2_ST	P28324	ELK4	P24941	CDK2	S180	S180Y	180	Missense	central	0	yes	12.829	0.000	EPSD	CCLE	8.148	Loss
CMGC_CDK_CDK2_CDK2_ST	P28324	ELK4	P24941	CDK2	T185	P181S	181	Missense	distal	-4	no	12.322	12.677	EPSD	CCLE	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	P28324	ELK4	P24941	CDK2	T185	S180Y	180	Missense	distal	-5	no	12.322	12.391	EPSD	CCLE	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	P28324	ELK4	P24941	CDK2	T420	S413F	413	Missense	distal	-7	no	13.564	14.115	EPSD	CCLE	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	P03372	ESR1	P24941	CDK2	S104	F97S	97	Missense	distal	-7	no	16.821	16.270	EPSD;PhosphoSitePlus	CCLE	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	P03372	ESR1	P24941	CDK2	S294	M297I	297	Missense	distal	3	no	12.927	12.499	EPSD;PhosphoSitePlus	CCLE	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	Q12778	FOXO1	P24941	CDK2	S329	S325T	325	Missense	distal	-4	no	11.834	11.646	EPSD	CCLE	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	Q12778	FOXO1	P24941	CDK2	S432	M431V	431	Missense	proximal	-1	no	13.610	12.517	EPSD	CCLE	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	Q12778	FOXO1	P24941	CDK2	S470	I476L	476	Missense	distal	6	no	15.813	15.814	EPSD	CCLE	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	Q12778	FOXO1	P24941	CDK2	T478	I476L	476	Missense	proximal	-2	no	13.501	13.431	EPSD	CCLE	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	O75533	SF3B1	P24941	CDK2	S541	L536I	536	Missense	distal	-5	no	13.379	13.407	EPSD	CCLE	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	P10644	PRKAR1A	P24941	CDK2	T209	Y207C	207	Missense	proximal	-2	no	13.976	13.479	EPSD	CCLE	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	Q92698	RAD54L	P24941	CDK2	T31	P32R	32	Missense	proximal	1	no	16.646	6.848	EPSD;PhosphoSitePlus	CCLE	8.148	Loss
CMGC_CDK_CDK2_CDK2_ST	P33981	TTK	P24941	CDK2	S49	T45N	45	Missense	distal	-4	no	8.301	8.273	EPSD	CCLE	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	P33981	TTK	P24941	CDK2	S80	L87F	87	Missense	distal	7	no	8.990	9.661	EPSD	CCLE	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	P33981	TTK	P24941	CDK2	S281	K287N	287	Missense	distal	6	no	8.574	8.569	EPSD	CCLE	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	Q53GL7	PARP10	P24941	CDK2	T310	V314A	314	Missense	distal	4	no	9.528	9.341	EPSD	CCLE	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	Q53GL7	PARP10	P24941	CDK2	S407	E411Q	411	Missense	distal	4	no	13.667	13.712	EPSD	CCLE	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	Q53ET0	CRTC2	P24941	CDK2	S368	H369P	369	Missense	proximal	1	no	7.913	14.672	EPSD	CCLE	8.148	Gain
CMGC_CDK_CDK2_CDK2_ST	Q53ET0	CRTC2	P24941	CDK2	S433	L438P	438	Missense	distal	5	no	13.266	13.226	PhosphoSitePlus	CCLE	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	Q53ET0	CRTC2	P24941	CDK2	S490	P484T	484	Missense	distal	-6	no	12.845	12.844	EPSD	CCLE	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	P31943	HNRNPH1	P24941	CDK2	S269	H274Y	274	Missense	distal	5	no	9.029	9.025	EPSD	CCLE	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	P31943	HNRNPH1	P24941	CDK2	S272	H274Y	274	Missense	proximal	2	no	8.746	8.727	EPSD	CCLE	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	Q99708	RBBP8	P24941	CDK2	S233	A236S	236	Missense	distal	3	no	13.121	13.667	EPSD	CCLE	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	Q99708	RBBP8	P24941	CDK2	S327	V325L	325	Missense	proximal	-2	no	13.862	14.287	EPSD	CCLE	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	Q99708	RBBP8	P24941	CDK2	S347	Q352P	352	Missense	distal	5	no	14.542	14.582	EPSD	CCLE	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	Q99708	RBBP8	P24941	CDK2	S568	P563A	563	Missense	distal	-5	no	14.873	14.898	EPSD	CCLE	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	Q9NYB0	TERF2IP	P24941	CDK2	T173	Q174P	174	Missense	proximal	1	no	3.128	11.040	EPSD	CCLE	8.148	Gain
CMGC_CDK_CDK2_CDK2_ST	P04183	TK1	P24941	CDK2	S13	S15R	15	Missense	proximal	2	no	15.982	16.074	PhosphoSitePlus	CCLE	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	A1KXE4	FAM168B	P24941	CDK2	S76	P77A	77	Missense	proximal	1	no	12.960	-1.443	EPSD	CCLE	8.148	Loss
CMGC_CDK_CDK2_CDK2_ST	A1KXE4	FAM168B	P24941	CDK2	T185	Y190C	190	Missense	distal	5	no	14.540	14.700	EPSD	CCLE	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	A1KXE4	FAM168B	P24941	CDK2	T185	T187N	187	Missense	proximal	2	no	14.540	14.647	EPSD	CCLE	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	Q96E09	FAM122A	P24941	CDK2	S19	P13R	13	Missense	distal	-6	no	12.120	12.122	EPSD	CCLE	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	Q96E09	FAM122A	P24941	CDK2	S48	S45G	45	Missense	distal	-3	no	16.531	16.539	EPSD	CCLE	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	Q96E09	FAM122A	P24941	CDK2	S48	V50A	50	Missense	proximal	2	no	16.531	16.433	EPSD	CCLE	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	Q96E09	FAM122A	P24941	CDK2	S257	S253Y	253	Missense	distal	-4	no	14.665	14.776	EPSD	CCLE	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	Q6P1N0	CC2D1A	P24941	CDK2	S253	M247V	247	Missense	distal	-6	no	14.311	14.305	EPSD	CCLE	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	Q6P1N0	CC2D1A	P24941	CDK2	T331	T334M	334	Missense	distal	3	no	13.394	13.269	EPSD	CCLE	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	Q53H80	AKIRIN2	P24941	CDK2	S125	A132T	132	Missense	distal	7	no	13.914	13.225	EPSD	CCLE	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	Q53H80	AKIRIN2	P24941	CDK2	S125	L120I	120	Missense	distal	-5	no	13.914	13.941	EPSD	CCLE	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	Q53H80	AKIRIN2	P24941	CDK2	S134	A132T	132	Missense	proximal	-2	no	18.141	18.091	EPSD	CCLE	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	P54198	HIRA	P24941	CDK2	S769	P776L	776	Missense	distal	7	no	11.894	11.924	EPSD	CCLE	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	P54198	HIRA	P24941	CDK2	S775	P776L	776	Missense	proximal	1	no	14.723	4.902	EPSD	CCLE	8.148	Loss
CMGC_CDK_CDK2_CDK2_ST	Q01167	FOXK2	P24941	CDK2	S30	S30A	30	Missense	central	0	yes	15.524	0.000	EPSD	CCLE	8.148	Loss
CMGC_CDK_CDK2_CDK2_ST	Q01167	FOXK2	P24941	CDK2	S30	P32L	32	Missense	proximal	2	no	15.524	15.417	EPSD	CCLE	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	Q01167	FOXK2	P24941	CDK2	S180	I179F	179	Missense	proximal	-1	no	10.223	11.026	EPSD	CCLE	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	Q01167	FOXK2	P24941	CDK2	S213	S212C	212	Missense	proximal	-1	no	14.683	15.027	EPSD	CCLE	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	Q01167	FOXK2	P24941	CDK2	S213	A217V	217	Missense	distal	4	no	14.683	14.870	EPSD	CCLE	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	Q01167	FOXK2	P24941	CDK2	S220	A217V	217	Missense	distal	-3	no	8.192	8.393	EPSD	CCLE	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	Q01167	FOXK2	P24941	CDK2	S220	V227L	227	Missense	distal	7	no	8.192	7.964	EPSD	CCLE	8.148	Loss
CMGC_CDK_CDK2_CDK2_ST	Q01167	FOXK2	P24941	CDK2	T360	L365F	365	Missense	distal	5	no	9.430	9.607	EPSD	CCLE	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	Q9Y2K7	KDM2A	P24941	CDK2	S394	R388W	388	Missense	distal	-6	no	14.691	14.697	EPSD	CCLE	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	Q9Y2K7	KDM2A	P24941	CDK2	S562	R566Q	566	Missense	distal	4	no	8.245	8.426	EPSD	CCLE	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	Q9Y2K7	KDM2A	P24941	CDK2	S781	G782C	782	Missense	proximal	1	no	8.153	-3.464	EPSD	CCLE	8.148	Loss
CMGC_CDK_CDK2_CDK2_ST	Q14207	NPAT	P24941	CDK2	S102	S108T	108	Missense	distal	6	no	12.263	12.270	EPSD	CCLE	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	Q14207	NPAT	P24941	CDK2	T1350	T1346I	1346	Missense	distal	-4	no	14.828	14.511	EPSD;PhosphoSitePlus	CCLE	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	Q01196	RUNX1	P24941	CDK2	S67	N69K	69	Missense	proximal	2	no	12.917	12.847	EPSD	CCLE	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	Q01196	RUNX1	P24941	CDK2	S249	T243A	243	Missense	distal	-6	no	12.126	12.125	EPSD	CCLE	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	Q01196	RUNX1	P24941	CDK2	S276	G282D	282	Missense	distal	6	no	17.102	17.098	PhosphoSitePlus;EPSD	CCLE	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	Q01196	RUNX1	P24941	CDK2	S304	D305N	305	Missense	proximal	1	no	11.112	-21.256	EPSD	CCLE	8.148	Loss
CMGC_CDK_CDK2_CDK2_ST	P49450	CENPA	P24941	CDK2	S17	P13Q	13	Missense	distal	-4	no	11.734	11.516	EPSD	CCLE	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	P49450	CENPA	P24941	CDK2	S17	S19T	19	Missense	proximal	2	no	11.734	11.490	EPSD	CCLE	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	P49450	CENPA	P24941	CDK2	S19	P13Q	13	Missense	distal	-6	no	13.670	13.673	PhosphoSitePlus	CCLE	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	P49450	CENPA	P24941	CDK2	T21	S19T	19	Missense	proximal	-2	no	12.414	13.032	EPSD	CCLE	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	P49450	CENPA	P24941	CDK2	T23	S19T	19	Missense	distal	-4	no	15.905	15.717	EPSD	CCLE	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	Q9NYF8	BCLAF1	P24941	CDK2	S104	H101Q	101	Missense	distal	-3	no	16.166	16.078	EPSD	CCLE	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	Q9NYF8	BCLAF1	P24941	CDK2	S114	R113I	113	Missense	proximal	-1	no	14.129	13.542	EPSD	CCLE	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	Q9NYF8	BCLAF1	P24941	CDK2	S222	P229R	229	Missense	distal	7	no	14.360	14.850	EPSD	CCLE	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	Q9NYF8	BCLAF1	P24941	CDK2	S225	P229R	229	Missense	distal	4	no	14.937	14.817	EPSD	CCLE	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	Q9NYF8	BCLAF1	P24941	CDK2	S228	P229R	229	Missense	proximal	1	no	12.823	3.024	EPSD	CCLE	8.148	Loss
CMGC_CDK_CDK2_CDK2_ST	Q9NYF8	BCLAF1	P24941	CDK2	S230	P229R	229	Missense	proximal	-1	no	11.833	12.404	EPSD	CCLE	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	Q9NYF8	BCLAF1	P24941	CDK2	T234	P229R	229	Missense	distal	-5	no	13.445	13.491	EPSD	CCLE	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	Q9NYF8	BCLAF1	P24941	CDK2	S385	G390A	390	Missense	distal	5	no	8.344	8.227	EPSD	CCLE	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	Q9NYF8	BCLAF1	P24941	CDK2	S389	G390A	390	Missense	proximal	1	no	9.361	2.270	EPSD	CCLE	8.148	Loss
CMGC_CDK_CDK2_CDK2_ST	Q9NYF8	BCLAF1	P24941	CDK2	T494	E493K	493	Missense	proximal	-1	no	8.177	7.292	EPSD	CCLE	8.148	Loss
CMGC_CDK_CDK2_CDK2_ST	Q9NYF8	BCLAF1	P24941	CDK2	T494	K492T	492	Missense	proximal	-2	no	8.177	8.658	EPSD	CCLE	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	Q9NYF8	BCLAF1	P24941	CDK2	S496	E493K	493	Missense	distal	-3	no	13.721	13.505	EPSD	CCLE	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	Q9NYF8	BCLAF1	P24941	CDK2	S496	K492T	492	Missense	distal	-4	no	13.721	13.968	EPSD	CCLE	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	Q9NYF8	BCLAF1	P24941	CDK2	S648	P649L	649	Missense	proximal	1	no	14.636	4.815	EPSD	CCLE	8.148	Loss
CMGC_CDK_CDK2_CDK2_ST	Q9NYF8	BCLAF1	P24941	CDK2	S658	S660R	660	Missense	proximal	2	no	13.774	13.866	EPSD	CCLE	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	Q9NYF8	BCLAF1	P24941	CDK2	S757	S752A	752	Missense	distal	-5	no	14.470	14.539	EPSD	CCLE	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	Q9UM11	FZR1	P24941	CDK2	S70	R63M	63	Missense	distal	-7	no	13.290	13.448	EPSD	CCLE	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	Q9UM11	FZR1	P24941	CDK2	T300	R299S	299	Missense	proximal	-1	no	14.296	13.254	EPSD	CCLE	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	Q08050	FOXM1	P24941	CDK2	S331	L334S	334	Missense	distal	3	no	15.331	15.748	EPSD	CCLE	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	Q08050	FOXM1	P24941	CDK2	S331	D328E	328	Missense	distal	-3	no	15.331	15.440	EPSD	CCLE	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	Q08050	FOXM1	P24941	CDK2	S340	L334S	334	Missense	distal	-6	no	11.158	11.157	EPSD	CCLE	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	Q08050	FOXM1	P24941	CDK2	S489	S493Y	493	Missense	distal	4	no	12.121	12.307	EPSD	CCLE	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	Q08050	FOXM1	P24941	CDK2	S508	K514N	514	Missense	distal	6	no	13.254	13.249	EPSD	CCLE	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	Q08050	FOXM1	P24941	CDK2	T510	K514N	514	Missense	distal	4	no	17.092	16.670	EPSD	CCLE	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	Q08050	FOXM1	P24941	CDK2	S518	K514N	514	Missense	distal	-4	no	9.017	9.237	EPSD	CCLE	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	Q00536	CDK16	P24941	CDK2	S138	E132Q	132	Missense	distal	-6	no	13.639	13.640	PhosphoSitePlus	CCLE	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	Q00536	CDK16	P24941	CDK2	S138	D142G	142	Missense	distal	4	no	13.639	13.584	PhosphoSitePlus	CCLE	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	Q9Y2W1	THRAP3	P24941	CDK2	S672	A667T	667	Missense	distal	-5	no	11.734	11.708	EPSD	CCLE	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	Q9Y2W1	THRAP3	P24941	CDK2	S682	S684N	684	Missense	proximal	2	no	13.357	13.220	EPSD	CCLE	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	Q9Y2W1	THRAP3	P24941	CDK2	S698	P699A	699	Missense	proximal	1	no	12.761	-1.643	EPSD	CCLE	8.148	Loss
CMGC_CDK_CDK2_CDK2_ST	Q9Y2W1	THRAP3	P24941	CDK2	S939	R944Q	944	Missense	distal	5	no	9.791	9.645	EPSD	CCLE	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	Q9Y2W1	THRAP3	P24941	CDK2	T941	R944Q	944	Missense	distal	3	no	10.445	8.702	EPSD	CCLE	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	P49736	MCM2	P24941	CDK2	S139	R133C	133	Missense	distal	-6	no	8.904	8.907	EPSD;PhosphoSitePlus	CCLE	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	P49736	MCM2	P24941	CDK2	S139	R133P	133	Missense	distal	-6	no	8.904	8.902	EPSD;PhosphoSitePlus	CCLE	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	P49736	MCM2	P24941	CDK2	S139	D143N	143	Missense	distal	4	no	8.904	8.949	EPSD;PhosphoSitePlus	CCLE	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	P49736	MCM2	P24941	CDK2	S381	G383D	383	Missense	proximal	2	no	17.631	17.511	EPSD	CCLE	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	P49736	MCM2	P24941	CDK2	T805	E800G	800	Missense	distal	-5	no	9.534	9.576	EPSD	CCLE	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	P55273	CDKN2D	P24941	CDK2	S76	G74C	74	Missense	proximal	-2	no	15.359	15.040	PhosphoSitePlus	CCLE	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	Q14191	WRN	P24941	CDK2	S453	D460G	460	Missense	distal	7	no	14.048	14.032	EPSD	CCLE	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	Q7Z2Z1	TICRR	P24941	CDK2	T486	S489I	489	Missense	distal	3	no	12.195	11.493	EPSD	CCLE	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	Q7Z2Z1	TICRR	P24941	CDK2	S489	S489I	489	Missense	central	0	yes	19.263	0.000	EPSD	CCLE	8.148	Loss
CMGC_CDK_CDK2_CDK2_ST	Q7Z2Z1	TICRR	P24941	CDK2	S599	P600S	600	Missense	proximal	1	no	15.711	4.445	EPSD	CCLE	8.148	Loss
CMGC_CDK_CDK2_CDK2_ST	Q7Z2Z1	TICRR	P24941	CDK2	S989	D990G	990	Missense	proximal	1	no	7.541	8.472	EPSD	CCLE	8.148	Gain
CMGC_CDK_CDK2_CDK2_ST	Q7Z2Z1	TICRR	P24941	CDK2	S1219	E1221K	1221	Missense	proximal	2	no	12.313	12.075	EPSD	CCLE	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	Q7Z2Z1	TICRR	P24941	CDK2	S1222	E1221K	1221	Missense	proximal	-1	no	8.606	7.721	EPSD	CCLE	8.148	Loss
CMGC_CDK_CDK2_CDK2_ST	Q7Z2Z1	TICRR	P24941	CDK2	T1250	F1257S	1257	Missense	distal	7	no	14.822	13.968	EPSD	CCLE	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	Q7Z2Z1	TICRR	P24941	CDK2	T1260	F1257S	1257	Missense	distal	-3	no	12.789	12.697	EPSD	CCLE	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	Q7Z2Z1	TICRR	P24941	CDK2	T1291	D1286Y	1286	Missense	distal	-5	no	15.267	15.234	EPSD	CCLE	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	Q7Z2Z1	TICRR	P24941	CDK2	S1447	W1449R	1449	Missense	proximal	2	no	9.800	9.703	EPSD	CCLE	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	Q7Z2Z1	TICRR	P24941	CDK2	S1453	W1449R	1449	Missense	distal	-4	no	14.539	15.297	EPSD	CCLE	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	Q7Z2Z1	TICRR	P24941	CDK2	S1517	D1524G	1524	Missense	distal	7	no	14.740	14.724	EPSD	CCLE	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	Q7Z2Z1	TICRR	P24941	CDK2	S1750	S1750L	1750	Missense	central	0	yes	16.013	0.000	EPSD	CCLE	8.148	Loss
CMGC_CDK_CDK2_CDK2_ST	Q7Z2Z1	TICRR	P24941	CDK2	S1806	G1805R	1805	Missense	proximal	-1	no	12.714	12.236	EPSD	CCLE	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	Q7Z2Z1	TICRR	P24941	CDK2	S1881	A1886T	1886	Missense	distal	5	no	13.327	13.292	EPSD	CCLE	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	P33991	MCM4	P24941	CDK2	S3	T7P	7	Missense	distal	4	no	9.879	9.597	EPSD	CCLE	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	P33991	MCM4	P24941	CDK2	S6	T7P	7	Missense	proximal	1	no	1.723	11.680	EPSD	CCLE	8.148	Gain
CMGC_CDK_CDK2_CDK2_ST	P33991	MCM4	P24941	CDK2	T7	T7P	7	Missense	central	0	yes	13.498	0.000	EPSD	CCLE	8.148	Loss
CMGC_CDK_CDK2_CDK2_ST	P33991	MCM4	P24941	CDK2	T19	G16E	16	Missense	distal	-3	no	13.630	13.701	EPSD	CCLE	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	P33991	MCM4	P24941	CDK2	T19	A21V	21	Missense	proximal	2	no	13.630	13.727	EPSD	CCLE	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	P33991	MCM4	P24941	CDK2	T23	G16E	16	Missense	distal	-7	no	12.603	12.368	EPSD	CCLE	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	P33991	MCM4	P24941	CDK2	T23	A21V	21	Missense	proximal	-2	no	12.603	11.937	EPSD	CCLE	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	P33991	MCM4	P24941	CDK2	T23	E27D	27	Missense	distal	4	no	12.603	12.521	EPSD	CCLE	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	P33991	MCM4	P24941	CDK2	S32	E27D	27	Missense	distal	-5	no	13.864	13.884	EPSD;PhosphoSitePlus	CCLE	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	P33991	MCM4	P24941	CDK2	S32	R37H	37	Missense	distal	5	no	13.864	13.836	EPSD;PhosphoSitePlus	CCLE	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	P33991	MCM4	P24941	CDK2	S54	P50S	50	Missense	distal	-4	no	15.106	15.460	EPSD;PhosphoSitePlus	CCLE	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	P06401	PGR	P24941	CDK2	S25	C29Y	29	Missense	distal	4	no	14.293	15.239	EPSD	CCLE	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	P06401	PGR	P24941	CDK2	S345	A348G	348	Missense	distal	3	no	13.491	13.902	EPSD	CCLE	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	P06401	PGR	P24941	CDK2	T351	A348G	348	Missense	distal	-3	no	13.300	13.462	EPSD	CCLE	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	P06401	PGR	P24941	CDK2	S676	I681V	681	Missense	distal	5	no	15.795	15.669	PhosphoSitePlus;EPSD	CCLE	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	O00571	DDX3X	P24941	CDK2	S90	S86G	86	Missense	distal	-4	no	11.904	11.231	EPSD	CCLE	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	O00571	DDX3X	P24941	CDK2	S90	S86R	86	Missense	distal	-4	no	11.904	11.306	EPSD	CCLE	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	O00571	DDX3X	P24941	CDK2	S92	S86G	86	Missense	distal	-6	no	9.795	9.799	EPSD	CCLE	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	O00571	DDX3X	P24941	CDK2	S92	S86R	86	Missense	distal	-6	no	9.795	9.798	EPSD	CCLE	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	O00571	DDX3X	P24941	CDK2	S489	K491R	491	Missense	proximal	2	no	8.315	8.615	EPSD	CCLE	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	O00571	DDX3X	P24941	CDK2	S492	K491R	491	Missense	proximal	-1	no	12.554	13.224	EPSD	CCLE	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	P18858	LIG1	P24941	CDK2	T183	D179N	179	Missense	distal	-4	no	16.795	16.407	EPSD	CCLE	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	P18858	LIG1	P24941	CDK2	T195	S199G	199	Missense	distal	4	no	15.007	14.874	EPSD	CCLE	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	P18858	LIG1	P24941	CDK2	T195	P196L	196	Missense	proximal	1	no	15.007	5.186	EPSD	CCLE	8.148	Loss
CMGC_CDK_CDK2_CDK2_ST	P18858	LIG1	P24941	CDK2	S323	V330I	330	Missense	distal	7	no	14.421	14.220	EPSD	CCLE	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	P18858	LIG1	P24941	CDK2	S913	D914H	914	Missense	proximal	1	no	7.813	9.298	EPSD	CCLE	8.148	Gain
CMGC_CDK_CDK2_CDK2_ST	Q96KS0	EGLN2	P24941	CDK2	S130	P129H	129	Missense	proximal	-1	no	15.587	15.707	PhosphoSitePlus	CCLE	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	Q9H2G4	TSPYL2	P24941	CDK2	S20	S16N	16	Missense	distal	-4	no	16.178	15.962	EPSD;PhosphoSitePlus	CCLE	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	P15923	TCF3	P24941	CDK2	S245	P238T	238	Missense	distal	-7	no	13.859	13.857	PhosphoSitePlus;EPSD	CCLE	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	P15923	TCF3	P24941	CDK2	T308	V304I	304	Missense	distal	-4	no	16.249	16.146	EPSD	CCLE	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	P15923	TCF3	P24941	CDK2	S341	S345L	345	Missense	distal	4	no	16.130	16.229	EPSD	CCLE	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	P15923	TCF3	P24941	CDK2	S352	S345L	345	Missense	distal	-7	no	12.332	12.518	EPSD	CCLE	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	P15923	TCF3	P24941	CDK2	S379	A377V	377	Missense	proximal	-2	no	13.318	12.652	EPSD	CCLE	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	P15923	TCF3	P24941	CDK2	S379	A374D	374	Missense	distal	-5	no	13.318	13.350	EPSD	CCLE	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	O60271	SPAG9	P24941	CDK2	T226	E230Q	230	Missense	distal	4	no	12.761	12.806	EPSD	CCLE	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	Q05516	ZBTB16	P24941	CDK2	T597	P601S	601	Missense	distal	4	no	12.433	12.446	EPSD	CCLE	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	P29374	ARID4A	P24941	CDK2	S789	E787D	787	Missense	proximal	-2	no	12.863	13.844	EPSD	CCLE	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	P29374	ARID4A	P24941	CDK2	S864	R870I	870	Missense	distal	6	no	20.135	20.152	PhosphoSitePlus;EPSD	CCLE	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	P29374	ARID4A	P24941	CDK2	S882	D888V	888	Missense	distal	6	no	9.849	9.863	EPSD	CCLE	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	P29374	ARID4A	P24941	CDK2	T1124	D1118E	1118	Missense	distal	-6	no	16.656	16.660	EPSD;PhosphoSitePlus	CCLE	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	P29374	ARID4A	P24941	CDK2	S1140	R1143K	1143	Missense	distal	3	no	15.316	16.305	EPSD;PhosphoSitePlus	CCLE	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	P29374	ARID4A	P24941	CDK2	S1140	P1146L	1146	Missense	distal	6	no	15.316	15.318	EPSD;PhosphoSitePlus	CCLE	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	P29374	ARID4A	P24941	CDK2	S1145	R1143K	1143	Missense	proximal	-2	no	15.244	15.965	EPSD;PhosphoSitePlus	CCLE	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	P29374	ARID4A	P24941	CDK2	S1145	P1146L	1146	Missense	proximal	1	no	15.244	5.423	EPSD;PhosphoSitePlus	CCLE	8.148	Loss
CMGC_CDK_CDK2_CDK2_ST	P29374	ARID4A	P24941	CDK2	S1145	G1151A	1151	Missense	distal	6	no	15.244	15.250	EPSD;PhosphoSitePlus	CCLE	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	Q5TZA2	CROCC	P24941	CDK2	S512	D517G	517	Missense	distal	5	no	10.715	10.668	EPSD	CCLE	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	Q5TZA2	CROCC	P24941	CDK2	S516	D517G	517	Missense	proximal	1	no	8.749	9.681	EPSD	CCLE	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	Q5TZA2	CROCC	P24941	CDK2	S602	R595W	595	Missense	distal	-7	no	8.174	8.344	EPSD	CCLE	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	Q5TZA2	CROCC	P24941	CDK2	S602	A609T	609	Missense	distal	7	no	8.174	7.485	EPSD	CCLE	8.148	Loss
CMGC_CDK_CDK2_CDK2_ST	Q5TZA2	CROCC	P24941	CDK2	S1451	P1450S	1450	Missense	proximal	-1	no	13.889	13.418	EPSD	CCLE	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	Q5TZA2	CROCC	P24941	CDK2	S1451	P1454Q	1454	Missense	distal	3	no	13.889	13.864	EPSD	CCLE	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	Q5TZA2	CROCC	P24941	CDK2	S1460	P1454Q	1454	Missense	distal	-6	no	19.305	19.308	EPSD	CCLE	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	Q5TZA2	CROCC	P24941	CDK2	S1939	S1937I	1937	Missense	proximal	-2	no	14.696	15.193	EPSD	CCLE	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	Q9NRH3	TUBG2	P24941	CDK2	T263	A258V	258	Missense	distal	-5	no	14.674	14.680	EPSD	CCLE	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	Q9NRH3	TUBG2	P24941	CDK2	T263	P262R	262	Missense	proximal	-1	no	14.674	15.245	EPSD	CCLE	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	Q12959	DLG1	P24941	CDK2	S100	L101P	101	Missense	proximal	1	no	2.393	12.214	EPSD	CCLE	8.148	Gain
CMGC_CDK_CDK2_CDK2_ST	Q12959	DLG1	P24941	CDK2	S102	L101P	101	Missense	proximal	-1	no	15.987	16.166	EPSD	CCLE	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	Q12959	DLG1	P24941	CDK2	S443	V450G	450	Missense	distal	7	no	15.997	16.408	PhosphoSitePlus;EPSD	CCLE	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	Q12959	DLG1	P24941	CDK2	S448	V450G	450	Missense	proximal	2	no	13.899	13.894	EPSD	CCLE	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	Q12959	DLG1	P24941	CDK2	T630	Q628H	628	Missense	proximal	-2	no	13.267	12.824	EPSD	CCLE	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	Q86T82	USP37	P24941	CDK2	S462	N461I	461	Missense	proximal	-1	no	12.626	12.683	EPSD	CCLE	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	Q86T82	USP37	P24941	CDK2	S628	T631A	631	Missense	distal	3	no	13.885	13.488	PhosphoSitePlus	CCLE	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	Q86T82	USP37	P24941	CDK2	T631	T631A	631	Missense	central	0	yes	15.733	0.000	EPSD	CCLE	8.148	Loss
CMGC_CDK_CDK2_CDK2_ST	Q86XL3	ANKLE2	P24941	CDK2	T406	T406P	406	Missense	central	0	yes	16.988	0.000	EPSD	CCLE	8.148	Loss
CMGC_CDK_CDK2_CDK2_ST	Q86XL3	ANKLE2	P24941	CDK2	S488	G492E	492	Missense	distal	4	no	13.370	13.506	EPSD	CCLE	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	Q86XL3	ANKLE2	P24941	CDK2	S496	G492E	492	Missense	distal	-4	no	16.120	16.668	EPSD	CCLE	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	Q86XL3	ANKLE2	P24941	CDK2	S556	H551Y	551	Missense	distal	-5	no	8.360	8.337	EPSD	CCLE	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	Q86XL3	ANKLE2	P24941	CDK2	S914	P915A	915	Missense	proximal	1	no	17.338	2.934	EPSD	CCLE	8.148	Loss
CMGC_CDK_CDK2_CDK2_ST	Q86XL3	ANKLE2	P24941	CDK2	S914	A908T	908	Missense	distal	-6	no	17.338	17.339	EPSD	CCLE	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	Q86XL3	ANKLE2	P24941	CDK2	S919	P915A	915	Missense	distal	-4	no	15.932	15.873	EPSD	CCLE	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	Q9H3P2	NELFA	P24941	CDK2	S233	R238Q	238	Missense	distal	5	no	13.090	12.944	EPSD	CCLE	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	Q9H3P2	NELFA	P24941	CDK2	T239	R238Q	238	Missense	proximal	-1	no	14.237	13.359	EPSD	CCLE	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	Q9H3P2	NELFA	P24941	CDK2	T297	E294D	294	Missense	distal	-3	no	11.544	11.435	EPSD	CCLE	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	Q9H3P2	NELFA	P24941	CDK2	T328	L325R	325	Missense	distal	-3	no	12.953	13.212	EPSD	CCLE	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	Q9H3P2	NELFA	P24941	CDK2	T343	R350W	350	Missense	distal	7	no	13.929	14.328	EPSD	CCLE	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	Q9H3P2	NELFA	P24941	CDK2	S363	F370L	370	Missense	distal	7	no	12.649	11.977	EPSD	CCLE	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	Q9H3P2	NELFA	P24941	CDK2	S363	P362L	362	Missense	proximal	-1	no	12.649	12.469	EPSD	CCLE	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	Q9H3P2	NELFA	P24941	CDK2	S363	S360N	360	Missense	distal	-3	no	12.649	12.574	EPSD	CCLE	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	Q9UKY1	ZHX1	P24941	CDK2	T36	G31D	31	Missense	distal	-5	no	15.400	15.378	EPSD	CCLE	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	Q9UKY1	ZHX1	P24941	CDK2	S774	N768D	768	Missense	distal	-6	no	8.270	8.269	EPSD	CCLE	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	P08621	SNRNP70	P24941	CDK2	S226	D232E	232	Missense	distal	6	no	15.254	15.266	PhosphoSitePlus	CCLE	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	P08621	SNRNP70	P24941	CDK2	S357	R355W	355	Missense	proximal	-2	no	9.664	9.164	EPSD	CCLE	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	Q14676	MDC1	P24941	CDK2	S202	E195K	195	Missense	distal	-7	no	13.551	13.414	EPSD	CCLE	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	Q14676	MDC1	P24941	CDK2	S882	E879G	879	Missense	distal	-3	no	14.584	14.513	EPSD	CCLE	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	Q14676	MDC1	P24941	CDK2	S990	R993M	993	Missense	distal	3	no	10.018	8.060	EPSD	CCLE	8.148	Loss
CMGC_CDK_CDK2_CDK2_ST	Q14676	MDC1	P24941	CDK2	S995	R993M	993	Missense	proximal	-2	no	12.126	11.278	EPSD	CCLE	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	Q14676	MDC1	P24941	CDK2	S998	R993M	993	Missense	distal	-5	no	17.115	17.175	EPSD	CCLE	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	Q14676	MDC1	P24941	CDK2	S1068	S1073Y	1073	Missense	distal	5	no	13.716	13.890	EPSD;PhosphoSitePlus	CCLE	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	Q14676	MDC1	P24941	CDK2	T1384	E1380K	1380	Missense	distal	-4	no	13.621	13.310	EPSD	CCLE	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	Q14676	MDC1	P24941	CDK2	T1384	S1378F	1378	Missense	distal	-6	no	13.621	13.626	EPSD	CCLE	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	Q14676	MDC1	P24941	CDK2	T1403	V1408L	1408	Missense	distal	5	no	12.170	12.243	EPSD	CCLE	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	Q14676	MDC1	P24941	CDK2	T1425	P1426S	1426	Missense	proximal	1	no	13.449	2.184	EPSD	CCLE	8.148	Loss
CMGC_CDK_CDK2_CDK2_ST	Q14676	MDC1	P24941	CDK2	T1589	T1589N	1589	Missense	central	0	yes	12.947	0.000	EPSD	CCLE	8.148	Loss
CMGC_CDK_CDK2_CDK2_ST	Q14676	MDC1	P24941	CDK2	T1664	D1659N	1659	Missense	distal	-5	no	12.247	12.209	EPSD	CCLE	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	Q14676	MDC1	P24941	CDK2	T1697	M1692I	1692	Missense	distal	-5	no	14.653	14.585	EPSD	CCLE	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	Q14676	MDC1	P24941	CDK2	T1781	Q1787H	1787	Missense	distal	6	no	12.270	12.260	EPSD	CCLE	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	Q14676	MDC1	P24941	CDK2	T1800	A1794V	1794	Missense	distal	-6	no	11.916	11.919	EPSD	CCLE	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	Q8WXE1	ATRIP	P24941	CDK2	T26	P30L	30	Missense	distal	4	no	10.946	11.058	EPSD	CCLE	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	P50613	CDK7	P24941	CDK2	S112	M118R	118	Missense	distal	6	no	11.467	11.470	EPSD	CCLE	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	Q9BZL4	PPP1R12C	P24941	CDK2	S288	M286I	286	Missense	proximal	-2	no	6.346	8.277	EPSD	CCLE	8.148	Gain
CMGC_CDK_CDK2_CDK2_ST	Q9BZL4	PPP1R12C	P24941	CDK2	S476	S483F	483	Missense	distal	7	no	12.262	13.116	EPSD	CCLE	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	Q9BZL4	PPP1R12C	P24941	CDK2	S499	E506D	506	Missense	distal	7	no	11.988	12.631	EPSD	CCLE	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	Q9BZL4	PPP1R12C	P24941	CDK2	S509	E506D	506	Missense	distal	-3	no	18.481	18.371	PhosphoSitePlus	CCLE	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	Q14194	CRMP1	P24941	CDK2	S304	D310N	310	Missense	distal	6	no	11.035	11.054	EPSD	CCLE	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	Q14194	CRMP1	P24941	CDK2	S308	D310N	310	Missense	proximal	2	no	13.825	13.757	EPSD	CCLE	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	Q96II8	LRCH3	P24941	CDK2	S16	Y15D	15	Missense	proximal	-1	no	8.306	8.623	EPSD	CCLE	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	Q96II8	LRCH3	P24941	CDK2	S419	R412W	412	Missense	distal	-7	no	18.277	18.448	PhosphoSitePlus	CCLE	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	Q96II8	LRCH3	P24941	CDK2	S419	K422N	422	Missense	distal	3	no	18.277	15.007	PhosphoSitePlus	CCLE	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	Q96II8	LRCH3	P24941	CDK2	S419	V424L	424	Missense	distal	5	no	18.277	18.350	PhosphoSitePlus	CCLE	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	Q96II8	LRCH3	P24941	CDK2	S628	H626Y	626	Missense	proximal	-2	no	11.754	12.200	EPSD	CCLE	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	P06400	RB1	P24941	CDK2	S37	P39S	39	Missense	proximal	2	no	8.308	8.374	EPSD	CCLE	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	P06400	RB1	P24941	CDK2	T373	M379T	379	Missense	distal	6	no	17.326	17.352	EPSD;PhosphoSitePlus	CCLE	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	P06400	RB1	P24941	CDK2	S608	P609H	609	Missense	proximal	1	no	15.720	8.961	EPSD;PhosphoSitePlus	CCLE	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	P06400	RB1	P24941	CDK2	S612	P609H	609	Missense	distal	-3	no	17.700	17.847	EPSD;PhosphoSitePlus	CCLE	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	O00267	SUPT5H	P24941	CDK2	S36	A34T	34	Missense	proximal	-2	no	8.329	8.280	EPSD	CCLE	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	O00267	SUPT5H	P24941	CDK2	S36	E43V	43	Missense	distal	7	no	8.329	8.543	EPSD	CCLE	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	O00267	SUPT5H	P24941	CDK2	T806	G811A	811	Missense	distal	5	no	17.093	16.976	EPSD	CCLE	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	O00267	SUPT5H	P24941	CDK2	T814	G811A	811	Missense	distal	-3	no	13.463	13.301	EPSD	CCLE	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	O00267	SUPT5H	P24941	CDK2	S847	G853E	853	Missense	distal	6	no	14.178	14.187	EPSD	CCLE	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	O00267	SUPT5H	P24941	CDK2	S847	T854P	854	Missense	distal	7	no	14.178	14.482	EPSD	CCLE	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	O00267	SUPT5H	P24941	CDK2	T854	G853E	853	Missense	proximal	-1	no	13.972	13.708	EPSD	CCLE	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	O00267	SUPT5H	P24941	CDK2	T854	T854P	854	Missense	central	0	yes	13.972	0.000	EPSD	CCLE	8.148	Loss
CMGC_CDK_CDK2_CDK2_ST	O00267	SUPT5H	P24941	CDK2	T859	T854P	854	Missense	distal	-5	no	14.122	14.123	EPSD	CCLE	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	O00267	SUPT5H	P24941	CDK2	S897	S891Y	891	Missense	distal	-6	no	12.335	12.336	EPSD	CCLE	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	O00267	SUPT5H	P24941	CDK2	S917	Y921C	921	Missense	distal	4	no	13.723	12.777	EPSD	CCLE	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	Q9UQR0	SCML2	P24941	CDK2	T305	K308E	308	Missense	distal	3	no	16.735	14.650	PhosphoSitePlus;EPSD	CCLE	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	P10275	AR	P24941	CDK2	S96	Q98R	98	Missense	proximal	2	no	13.938	14.038	PhosphoSitePlus	CCLE	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	O43395	PRPF3	P24941	CDK2	S164	T167A	167	Missense	distal	3	no	13.379	12.981	EPSD	CCLE	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	O43395	PRPF3	P24941	CDK2	T167	T167A	167	Missense	central	0	yes	14.827	0.000	PhosphoSitePlus	CCLE	8.148	Loss
CMGC_CDK_CDK2_CDK2_ST	O43395	PRPF3	P24941	CDK2	T172	T167A	167	Missense	distal	-5	no	13.442	13.468	EPSD	CCLE	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	O43395	PRPF3	P24941	CDK2	S320	R322H	322	Missense	proximal	2	no	10.036	9.955	EPSD	CCLE	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	P46527	CDKN1B	P24941	CDK2	S10	S12I	12	Missense	proximal	2	no	12.148	12.059	EPSD	CCLE	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	Q13415	ORC1	P24941	CDK2	T224	K220N	220	Missense	distal	-4	no	11.701	11.920	EPSD	CCLE	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	P54132	BLM	P24941	CDK2	S304	I309F	309	Missense	distal	5	no	12.972	13.097	EPSD	CCLE	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	P54132	BLM	P24941	CDK2	S328	D329H	329	Missense	proximal	1	no	9.400	10.885	EPSD	CCLE	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	P54132	BLM	P24941	CDK2	S426	D420E	420	Missense	distal	-6	no	9.048	9.052	EPSD	CCLE	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	P54132	BLM	P24941	CDK2	S714	V721T	721	Missense	distal	7	no	14.707	14.144	EPSD	CCLE	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	O00429	DNM1L	P24941	CDK2	S548	S548P	548	Missense	central	0	yes	14.167	0.000	EPSD	CCLE	8.148	Loss
CMGC_CDK_CDK2_CDK2_ST	Q8IXM2	C17orf49	P24941	CDK2	S36	H30R	30	Missense	distal	-6	no	12.637	12.635	EPSD	CCLE	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	P28749	RBL1	P24941	CDK2	T369	R374W	374	Missense	distal	5	no	12.875	13.042	EPSD	CCLE	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	P28749	RBL1	P24941	CDK2	S640	M636I	636	Missense	distal	-4	no	14.260	14.858	EPSD;PhosphoSitePlus	CCLE	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	P28749	RBL1	P24941	CDK2	S749	L753R	753	Missense	distal	4	no	13.135	12.902	EPSD	CCLE	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	P13051	UNG	P24941	CDK2	S12	F10L	10	Missense	proximal	-2	no	13.559	14.447	PhosphoSitePlus;EPSD	CCLE	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	P13051	UNG	P24941	CDK2	S14	F10L	10	Missense	distal	-4	no	14.457	15.006	EPSD	CCLE	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	Q92547	TOPBP1	P24941	CDK2	T779	V778A	778	Missense	proximal	-1	no	11.270	11.043	EPSD	CCLE	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	Q92785	DPF2	P24941	CDK2	T248	V250I	250	Missense	proximal	2	no	15.200	15.055	EPSD	CCLE	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	Q92785	DPF2	P24941	CDK2	T358	E363D	363	Missense	distal	5	no	11.160	11.254	EPSD	CCLE	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	Q9UEY8	ADD3	P24941	CDK2	S600	S596C	596	Missense	distal	-4	no	12.579	11.473	EPSD	CCLE	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	Q0VD86	INCA1	P24941	CDK2	T182	G184S	184	Missense	proximal	2	no	16.451	16.400	EPSD;PhosphoSitePlus	CCLE	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	Q0VD86	INCA1	P24941	CDK2	S191	G184S	184	Missense	distal	-7	no	13.226	12.722	PhosphoSitePlus;EPSD	CCLE	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	P61978	HNRNPK	P24941	CDK2	S116	T120I	120	Missense	distal	4	no	14.915	14.603	EPSD	CCLE	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	P61978	HNRNPK	P24941	CDK2	S216	R221C	221	Missense	distal	5	no	19.794	19.921	EPSD;PhosphoSitePlus	CCLE	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	P42677	RPS27	P24941	CDK2	S27	N29S	29	Missense	proximal	2	no	15.410	15.547	PhosphoSitePlus	CCLE	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	O00311	CDC7	P24941	CDK2	S302	V305E	305	Missense	distal	3	no	13.608	13.621	EPSD	CCLE	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	P24941	CDK2	P24941	CDK2	S53	E51D	51	Missense	proximal	-2	no	7.783	8.764	EPSD	CCLE	8.148	Gain
CMGC_CDK_CDK2_CDK2_ST	Q14980	NUMA1	P24941	CDK2	S169	A175T	175	Missense	distal	6	no	9.491	9.502	EPSD	CCLE	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	Q14980	NUMA1	P24941	CDK2	S271	A269P	269	Missense	proximal	-2	no	13.707	13.691	EPSD	CCLE	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	Q14980	NUMA1	P24941	CDK2	S1862	D1864N	1864	Missense	proximal	2	no	14.132	14.064	EPSD	CCLE	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	Q14980	NUMA1	P24941	CDK2	T2106	A2101T	2101	Missense	distal	-5	no	13.905	13.879	EPSD	CCLE	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	Q15717	ELAVL1	P24941	CDK2	S202	A204V	204	Missense	proximal	2	no	15.691	15.789	PhosphoSitePlus	CCLE	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	Q15717	ELAVL1	P24941	CDK2	S221	G224D	224	Missense	distal	3	no	13.732	12.020	EPSD	CCLE	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	Q14103	HNRNPD	P24941	CDK2	S190	D192V	192	Missense	proximal	2	no	12.015	12.140	EPSD	CCLE	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	Q14103	HNRNPD	P24941	CDK2	T193	D192V	192	Missense	proximal	-1	no	15.027	14.228	PhosphoSitePlus	CCLE	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	P31350	RRM2	P24941	CDK2	S377	E380Q	380	Missense	distal	3	no	12.856	12.209	EPSD	CCLE	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	Q9C0C2	TNKS1BP1	P24941	CDK2	S14	R18W	18	Missense	distal	4	no	9.834	9.475	EPSD	CCLE	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	Q9C0C2	TNKS1BP1	P24941	CDK2	T131	A138T	138	Missense	distal	7	no	11.902	11.213	EPSD	CCLE	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	Q9C0C2	TNKS1BP1	P24941	CDK2	S275	P276L	276	Missense	proximal	1	no	13.397	3.576	EPSD	CCLE	8.148	Loss
CMGC_CDK_CDK2_CDK2_ST	Q9C0C2	TNKS1BP1	P24941	CDK2	S287	A292T	292	Missense	distal	5	no	14.401	14.365	EPSD	CCLE	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	Q9C0C2	TNKS1BP1	P24941	CDK2	S297	A292T	292	Missense	distal	-5	no	8.314	8.288	EPSD	CCLE	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	Q9C0C2	TNKS1BP1	P24941	CDK2	S311	H314L	314	Missense	distal	3	no	13.207	11.802	EPSD	CCLE	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	Q9C0C2	TNKS1BP1	P24941	CDK2	S329	V334L	334	Missense	distal	5	no	11.667	11.740	EPSD	CCLE	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	Q9C0C2	TNKS1BP1	P24941	CDK2	T335	P339S	339	Missense	distal	4	no	12.229	12.242	EPSD	CCLE	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	Q9C0C2	TNKS1BP1	P24941	CDK2	T335	V334L	334	Missense	proximal	-1	no	12.229	12.093	EPSD	CCLE	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	Q9C0C2	TNKS1BP1	P24941	CDK2	S494	I500L	500	Missense	distal	6	no	13.077	13.078	EPSD	CCLE	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	Q9C0C2	TNKS1BP1	P24941	CDK2	S498	I500L	500	Missense	proximal	2	no	15.064	14.980	EPSD	CCLE	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	Q9C0C2	TNKS1BP1	P24941	CDK2	T578	L581S	581	Missense	distal	3	no	12.772	13.190	EPSD	CCLE	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	Q9C0C2	TNKS1BP1	P24941	CDK2	S987	G985V	985	Missense	proximal	-2	no	14.426	14.519	EPSD	CCLE	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	Q9C0C2	TNKS1BP1	P24941	CDK2	S1029	V1035M	1035	Missense	distal	6	no	14.499	14.482	EPSD	CCLE	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	Q9C0C2	TNKS1BP1	P24941	CDK2	S1371	V1367A	1367	Missense	distal	-4	no	9.296	9.285	EPSD	CCLE	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	Q9H8Y8	GORASP2	P24941	CDK2	T415	K420N	420	Missense	distal	5	no	11.553	11.710	EPSD	CCLE	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	Q9H8Y8	GORASP2	P24941	CDK2	T433	V435L	435	Missense	proximal	2	no	15.225	14.996	EPSD	CCLE	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	Q9H8Y8	GORASP2	P24941	CDK2	T433	K438R	438	Missense	distal	5	no	15.225	15.385	EPSD	CCLE	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	Q9Y253	POLH	P24941	CDK2	S687	N693D	693	Missense	distal	6	no	13.920	13.901	PhosphoSitePlus	CCLE	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	P25054	APC	P24941	CDK2	T600	E601D	601	Missense	proximal	1	no	7.888	8.810	EPSD	CCLE	8.148	Gain
CMGC_CDK_CDK2_CDK2_ST	P25054	APC	P24941	CDK2	S1042	S1044L	1044	Missense	proximal	2	no	14.087	13.914	EPSD	CCLE	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	P25054	APC	P24941	CDK2	S1465	T1459I	1459	Missense	distal	-6	no	9.874	9.876	EPSD	CCLE	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	P25054	APC	P24941	CDK2	S1465	S1465C	1465	Missense	central	0	yes	9.874	0.000	EPSD	CCLE	8.148	Loss
CMGC_CDK_CDK2_CDK2_ST	P25054	APC	P24941	CDK2	S1664	T1661K	1661	Missense	distal	-3	no	13.896	13.895	EPSD	CCLE	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	P25054	APC	P24941	CDK2	S1737	H1738P	1738	Missense	proximal	1	no	3.883	10.642	EPSD	CCLE	8.148	Gain
CMGC_CDK_CDK2_CDK2_ST	P25054	APC	P24941	CDK2	T2017	E2015G	2015	Missense	proximal	-2	no	8.849	9.222	EPSD	CCLE	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	P25054	APC	P24941	CDK2	T2255	S2260N	2260	Missense	distal	5	no	11.583	11.787	EPSD	CCLE	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	P25054	APC	P24941	CDK2	S2260	S2260N	2260	Missense	central	0	yes	13.997	0.000	EPSD	CCLE	8.148	Loss
CMGC_CDK_CDK2_CDK2_ST	P25054	APC	P24941	CDK2	S2350	L2345I	2345	Missense	distal	-5	no	13.220	13.247	EPSD	CCLE	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	P25054	APC	P24941	CDK2	S2368	S2361F	2361	Missense	distal	-7	no	16.725	17.276	EPSD	CCLE	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	P25054	APC	P24941	CDK2	S2512	T2514I	2514	Missense	proximal	2	no	12.667	12.822	EPSD	CCLE	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	P25054	APC	P24941	CDK2	S2621	F2620C	2620	Missense	proximal	-1	no	11.510	10.597	EPSD	CCLE	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	P25054	APC	P24941	CDK2	T2760	I2756V	2756	Missense	distal	-4	no	13.102	13.204	EPSD	CCLE	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	P25054	APC	P24941	CDK2	S2772	S2768R	2768	Missense	distal	-4	no	10.099	9.501	EPSD	CCLE	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	Q13118	KLF10	P24941	CDK2	T93	T93N	93	Missense	central	0	yes	11.657	0.000	EPSD	CCLE	8.148	Loss
CMGC_CDK_CDK2_CDK2_ST	Q13118	KLF10	P24941	CDK2	S97	T93N	93	Missense	distal	-4	no	13.807	13.778	EPSD	CCLE	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	Q13118	KLF10	P24941	CDK2	S206	N199T	199	Missense	distal	-7	no	14.452	14.530	PhosphoSitePlus	CCLE	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	Q13118	KLF10	P24941	CDK2	S384	R391G	391	Missense	distal	7	no	9.740	9.921	EPSD	CCLE	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	Q13118	KLF10	P24941	CDK2	T394	R391G	391	Missense	distal	-3	no	8.999	8.913	EPSD	CCLE	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	Q13118	KLF10	P24941	CDK2	S441	M439T	439	Missense	proximal	-2	no	6.118	8.169	EPSD	CCLE	8.148	Gain
CMGC_CDK_CDK2_CDK2_ST	Q9C0C9	UBE2O	P24941	CDK2	S99	E93K	93	Missense	distal	-6	no	8.711	8.708	EPSD	CCLE	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	Q9C0C9	UBE2O	P24941	CDK2	S115	Y121C	121	Missense	distal	6	no	18.115	18.109	EPSD	CCLE	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	Q9C0C9	UBE2O	P24941	CDK2	S836	T834M	834	Missense	proximal	-2	no	13.935	11.884	PhosphoSitePlus	CCLE	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	Q9C0C9	UBE2O	P24941	CDK2	S839	T834M	834	Missense	distal	-5	no	13.018	13.126	EPSD	CCLE	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	P23258	TUBG1	P24941	CDK2	T45	V50G	50	Missense	distal	5	no	10.767	10.927	EPSD	CCLE	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	P23258	TUBG1	P24941	CDK2	S364	V358L	358	Missense	distal	-6	no	11.482	11.481	EPSD	CCLE	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	P23258	TUBG1	P24941	CDK2	S364	S369L	369	Missense	distal	5	no	11.482	11.623	EPSD	CCLE	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	Q9ULW0	TPX2	P24941	CDK2	T59	L61W	61	Missense	proximal	2	no	12.983	13.345	EPSD	CCLE	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	Q9ULW0	TPX2	P24941	CDK2	T113	R120K	120	Missense	distal	7	no	12.783	12.007	EPSD	CCLE	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	Q9ULW0	TPX2	P24941	CDK2	S293	S293F	293	Missense	central	0	yes	15.428	0.000	EPSD	CCLE	8.148	Loss
CMGC_CDK_CDK2_CDK2_ST	O14686	KMT2D	P24941	CDK2	S579	M581T	581	Missense	proximal	2	no	14.706	14.318	EPSD	CCLE	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	O14686	KMT2D	P24941	CDK2	S582	E587Q	587	Missense	distal	5	no	13.351	13.232	EPSD	CCLE	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	O14686	KMT2D	P24941	CDK2	S582	M581T	581	Missense	proximal	-1	no	13.351	12.038	EPSD	CCLE	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	O14686	KMT2D	P24941	CDK2	S588	E587Q	587	Missense	proximal	-1	no	13.239	12.147	EPSD	CCLE	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	O14686	KMT2D	P24941	CDK2	S588	M581T	581	Missense	distal	-7	no	13.239	12.735	EPSD	CCLE	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	O14686	KMT2D	P24941	CDK2	S591	E587Q	587	Missense	distal	-4	no	14.123	13.674	EPSD	CCLE	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	O14686	KMT2D	P24941	CDK2	S627	P634S	634	Missense	distal	7	no	12.679	12.527	EPSD	CCLE	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	O14686	KMT2D	P24941	CDK2	S633	P634S	634	Missense	proximal	1	no	13.703	2.437	EPSD	CCLE	8.148	Loss
CMGC_CDK_CDK2_CDK2_ST	O14686	KMT2D	P24941	CDK2	S636	P634S	634	Missense	proximal	-2	no	13.957	13.306	EPSD	CCLE	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	O14686	KMT2D	P24941	CDK2	S654	L653I	653	Missense	proximal	-1	no	11.205	11.367	EPSD	CCLE	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	O14686	KMT2D	P24941	CDK2	S762	E767A	767	Missense	distal	5	no	12.215	12.146	EPSD	CCLE	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	O14686	KMT2D	P24941	CDK2	T1164	P1162H	1162	Missense	proximal	-2	no	13.764	12.754	EPSD	CCLE	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	O14686	KMT2D	P24941	CDK2	T1195	L1199V	1199	Missense	distal	4	no	14.225	14.340	EPSD	CCLE	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	O14686	KMT2D	P24941	CDK2	T1195	P1197H	1197	Missense	proximal	2	no	14.225	14.302	EPSD	CCLE	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	O14686	KMT2D	P24941	CDK2	S1280	K1283N	1283	Missense	distal	3	no	8.271	5.000	EPSD	CCLE	8.148	Loss
CMGC_CDK_CDK2_CDK2_ST	O14686	KMT2D	P24941	CDK2	T1843	G1850S	1850	Missense	distal	7	no	16.149	15.327	EPSD	CCLE	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	O14686	KMT2D	P24941	CDK2	S1854	G1850S	1850	Missense	distal	-4	no	15.691	16.363	EPSD	CCLE	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	O14686	KMT2D	P24941	CDK2	T1911	S1917N	1917	Missense	distal	6	no	12.443	12.445	EPSD	CCLE	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	O14686	KMT2D	P24941	CDK2	T1919	S1917N	1917	Missense	proximal	-2	no	12.736	12.044	EPSD	CCLE	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	O14686	KMT2D	P24941	CDK2	T2323	T2323A	2323	Missense	central	0	yes	14.175	0.000	EPSD	CCLE	8.148	Loss
CMGC_CDK_CDK2_CDK2_ST	O14686	KMT2D	P24941	CDK2	S2592	G2591C	2591	Missense	proximal	-1	no	13.596	12.420	EPSD	CCLE	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	O14686	KMT2D	P24941	CDK2	T2959	N2965T	2965	Missense	distal	6	no	8.464	8.468	EPSD	CCLE	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	O14686	KMT2D	P24941	CDK2	S4974	R4975H	4975	Missense	proximal	1	no	5.535	8.575	EPSD	CCLE	8.148	Gain
CMGC_CDK_CDK2_CDK2_ST	P29590	PML	P24941	CDK2	T391	L386P	386	Missense	distal	-5	no	9.259	9.247	EPSD	CCLE	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	Q13242	SRSF9	P24941	CDK2	S109	V113A	113	Missense	distal	4	no	9.381	9.193	EPSD	CCLE	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	Q13242	SRSF9	P24941	CDK2	S197	R196Q	196	Missense	proximal	-1	no	9.099	8.221	EPSD	CCLE	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	Q05682	CALD1	P24941	CDK2	S155	R156H	156	Missense	proximal	1	no	6.169	9.209	EPSD	CCLE	8.148	Gain
CMGC_CDK_CDK2_CDK2_ST	Q05682	CALD1	P24941	CDK2	S248	D249G	249	Missense	proximal	1	no	8.295	9.226	EPSD	CCLE	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	Q05682	CALD1	P24941	CDK2	S252	D249G	249	Missense	distal	-3	no	8.892	8.931	EPSD	CCLE	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	Q05682	CALD1	P24941	CDK2	S724	F722L	722	Missense	proximal	-2	no	12.072	12.961	EPSD	CCLE	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	Q05682	CALD1	P24941	CDK2	T730	T735I	735	Missense	distal	5	no	17.797	17.915	PhosphoSitePlus	CCLE	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	P49916	LIG3	P24941	CDK2	S242	G237E	237	Missense	distal	-5	no	11.280	11.237	EPSD	CCLE	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	P49916	LIG3	P24941	CDK2	S242	S242R	242	Missense	central	0	yes	11.280	0.000	EPSD	CCLE	8.148	Loss
CMGC_CDK_CDK2_CDK2_ST	P49916	LIG3	P24941	CDK2	T244	G237E	237	Missense	distal	-7	no	14.796	14.562	EPSD	CCLE	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	P49916	LIG3	P24941	CDK2	T244	S242R	242	Missense	proximal	-2	no	14.796	14.211	EPSD	CCLE	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	P48634	PRRC2A	P24941	CDK2	S19	L20P	20	Missense	proximal	1	no	2.647	12.468	EPSD	CCLE	8.148	Gain
CMGC_CDK_CDK2_CDK2_ST	P48634	PRRC2A	P24941	CDK2	T132	A127T	127	Missense	distal	-5	no	14.276	14.250	EPSD	CCLE	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	P48634	PRRC2A	P24941	CDK2	T132	P133L	133	Missense	proximal	1	no	14.276	4.455	EPSD	CCLE	8.148	Loss
CMGC_CDK_CDK2_CDK2_ST	P48634	PRRC2A	P24941	CDK2	T132	L134S	134	Missense	proximal	2	no	14.276	14.450	EPSD	CCLE	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	P48634	PRRC2A	P24941	CDK2	S1004	A1006P	1006	Missense	proximal	2	no	15.107	15.082	EPSD	CCLE	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	P48634	PRRC2A	P24941	CDK2	S1186	P1179N	1179	Missense	distal	-7	no	12.590	12.508	EPSD	CCLE	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	P48634	PRRC2A	P24941	CDK2	S1306	K1305R	1305	Missense	proximal	-1	no	14.241	14.912	EPSD	CCLE	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	P48634	PRRC2A	P24941	CDK2	S1435	R1441H	1441	Missense	distal	6	no	10.150	10.162	EPSD	CCLE	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	P48634	PRRC2A	P24941	CDK2	S1554	P1557T	1557	Missense	distal	3	no	12.805	12.691	EPSD	CCLE	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	P48634	PRRC2A	P24941	CDK2	S2098	R2102C	2102	Missense	distal	4	no	9.042	8.415	EPSD	CCLE	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	Q71UM5	RPS27L	P24941	CDK2	S27	K22N	22	Missense	distal	-5	no	15.431	15.447	PhosphoSitePlus	CCLE	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	O95251	KAT7	P24941	CDK2	S148	A154D	154	Missense	distal	6	no	10.590	10.579	EPSD	CCLE	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	O15014	ZNF609	P24941	CDK2	S275	S275C	275	Missense	central	0	yes	12.468	0.000	EPSD	CCLE	8.148	Loss
CMGC_CDK_CDK2_CDK2_ST	O15014	ZNF609	P24941	CDK2	T381	T381A	381	Missense	central	0	yes	10.192	0.000	EPSD	CCLE	8.148	Loss
CMGC_CDK_CDK2_CDK2_ST	O15014	ZNF609	P24941	CDK2	S390	D391E	391	Missense	proximal	1	no	8.528	7.606	EPSD	CCLE	8.148	Loss
CMGC_CDK_CDK2_CDK2_ST	O15014	ZNF609	P24941	CDK2	S1267	K1272N	1272	Missense	distal	5	no	13.626	13.783	EPSD	CCLE	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	O15014	ZNF609	P24941	CDK2	S1285	K1281R	1281	Missense	distal	-4	no	13.880	13.718	EPSD	CCLE	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	O15014	ZNF609	P24941	CDK2	S1313	T1320N	1320	Missense	distal	7	no	13.990	14.200	EPSD	CCLE	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	Q9Y3Z3	SAMHD1	P24941	CDK2	S33	S33F	33	Missense	central	0	yes	14.172	0.000	EPSD	CCLE	8.148	Loss
CMGC_CDK_CDK2_CDK2_ST	O14497	ARID1A	P24941	CDK2	S157	A160V	160	Missense	distal	3	no	13.586	14.706	EPSD	CCLE	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	O14497	ARID1A	P24941	CDK2	S233	G237S	237	Missense	distal	4	no	13.642	13.775	EPSD	CCLE	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	O14497	ARID1A	P24941	CDK2	S233	P239S	239	Missense	distal	6	no	13.642	13.643	EPSD	CCLE	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	O14497	ARID1A	P24941	CDK2	T238	G237S	237	Missense	proximal	-1	no	12.964	11.445	EPSD	CCLE	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	O14497	ARID1A	P24941	CDK2	T238	P239S	239	Missense	proximal	1	no	12.964	1.698	EPSD	CCLE	8.148	Loss
CMGC_CDK_CDK2_CDK2_ST	O14497	ARID1A	P24941	CDK2	S317	S317G	317	Missense	central	0	yes	8.926	0.000	EPSD	CCLE	8.148	Loss
CMGC_CDK_CDK2_CDK2_ST	O14497	ARID1A	P24941	CDK2	S964	N957S	957	Missense	distal	-7	no	14.072	13.974	EPSD	CCLE	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	O14497	ARID1A	P24941	CDK2	S964	P965T	965	Missense	proximal	1	no	14.072	4.115	EPSD	CCLE	8.148	Loss
CMGC_CDK_CDK2_CDK2_ST	O14497	ARID1A	P24941	CDK2	S1316	P1321R	1321	Missense	distal	5	no	8.789	8.895	EPSD	CCLE	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	O14497	ARID1A	P24941	CDK2	S1320	P1321R	1321	Missense	proximal	1	no	15.061	5.263	EPSD	CCLE	8.148	Loss
CMGC_CDK_CDK2_CDK2_ST	O14497	ARID1A	P24941	CDK2	S1320	Y1324H	1324	Missense	distal	4	no	15.061	14.624	EPSD	CCLE	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	O14497	ARID1A	P24941	CDK2	T1348	Q1346R	1346	Missense	proximal	-2	no	15.419	14.750	EPSD	CCLE	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	O14497	ARID1A	P24941	CDK2	S1352	Q1346R	1346	Missense	distal	-6	no	14.485	14.484	EPSD	CCLE	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	Q7KZ85	SUPT6H	P24941	CDK2	T619	T619N	619	Missense	central	0	yes	12.869	0.000	EPSD	CCLE	8.148	Loss
CMGC_CDK_CDK2_CDK2_ST	Q7KZ85	SUPT6H	P24941	CDK2	T1523	S1528R	1528	Missense	distal	5	no	11.752	11.960	PhosphoSitePlus	CCLE	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	Q7KZ85	SUPT6H	P24941	CDK2	T1532	S1528R	1528	Missense	distal	-4	no	13.927	13.330	EPSD	CCLE	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	Q7KZ85	SUPT6H	P24941	CDK2	T1618	T1624A	1624	Missense	distal	6	no	12.531	12.520	EPSD	CCLE	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	Q12948	FOXC1	P24941	CDK2	S9	V16A	16	Missense	distal	7	no	12.591	12.718	EPSD	CCLE	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	Q12948	FOXC1	P24941	CDK2	S320	S316L	316	Missense	distal	-4	no	12.361	11.948	EPSD	CCLE	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	Q12948	FOXC1	P24941	CDK2	S320	S320W	320	Missense	central	0	yes	12.361	0.000	EPSD	CCLE	8.148	Loss
CMGC_CDK_CDK2_CDK2_ST	Q12948	FOXC1	P24941	CDK2	S521	R515M	515	Missense	distal	-6	no	8.496	8.501	EPSD	CCLE	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	Q15047	SETDB1	P24941	CDK2	T443	E449G	449	Missense	distal	6	no	9.880	9.871	EPSD	CCLE	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	Q6PKG0	LARP1	P24941	CDK2	T649	T647N	647	Missense	proximal	-2	no	11.569	10.259	PhosphoSitePlus;EPSD	CCLE	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	Q8NBZ0	INO80E	P24941	CDK2	S106	G102R	102	Missense	distal	-4	no	10.328	10.403	EPSD	CCLE	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	Q9UPN3	MACF1	P24941	CDK2	S907	T909S	909	Missense	proximal	2	no	13.460	13.704	EPSD	CCLE	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	Q9UPN3	MACF1	P24941	CDK2	S1363	Y1357C	1357	Missense	distal	-6	no	9.734	9.740	EPSD	CCLE	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	Q9UPN3	MACF1	P24941	CDK2	T2160	P2161L	2161	Missense	proximal	1	no	18.674	8.853	EPSD	CCLE	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	Q9UPN3	MACF1	P24941	CDK2	S2517	I2513F	2513	Missense	distal	-4	no	9.704	9.247	EPSD	CCLE	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	Q9UPN3	MACF1	P24941	CDK2	T2586	E2581K	2581	Missense	distal	-5	no	8.477	8.442	EPSD	CCLE	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	Q9UPN3	MACF1	P24941	CDK2	S2647	G2648A	2648	Missense	proximal	1	no	9.433	2.342	EPSD	CCLE	8.148	Loss
CMGC_CDK_CDK2_CDK2_ST	Q9UPN3	MACF1	P24941	CDK2	T3111	P3108T	3108	Missense	distal	-3	no	11.096	11.056	EPSD	CCLE	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	Q9UPN3	MACF1	P24941	CDK2	S3298	P3299S	3299	Missense	proximal	1	no	15.057	3.791	EPSD	CCLE	8.148	Loss
CMGC_CDK_CDK2_CDK2_ST	Q9UPN3	MACF1	P24941	CDK2	S4496	M4491V	4491	Missense	distal	-5	no	13.903	13.827	EPSD	CCLE	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	Q9UPN3	MACF1	P24941	CDK2	S5592	P5593S	5593	Missense	proximal	1	no	13.211	1.945	EPSD	CCLE	8.148	Loss
CMGC_CDK_CDK2_CDK2_ST	Q9UPN3	MACF1	P24941	CDK2	S7230	R7227Q	7227	Missense	distal	-3	no	15.485	15.355	EPSD	CCLE	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	Q9UPN3	MACF1	P24941	CDK2	S7230	R7233H	7233	Missense	distal	3	no	15.485	14.788	EPSD	CCLE	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	Q9UPN3	MACF1	P24941	CDK2	S7251	M7248I	7248	Missense	distal	-3	no	14.261	13.913	EPSD	CCLE	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	Q9UPN3	MACF1	P24941	CDK2	T7254	M7248I	7248	Missense	distal	-6	no	12.488	12.483	EPSD	CCLE	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	Q9UPN3	MACF1	P24941	CDK2	T7273	T7275A	7275	Missense	proximal	2	no	11.902	12.104	EPSD	CCLE	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	Q9UPN3	MACF1	P24941	CDK2	S7292	N7289S	7289	Missense	distal	-3	no	15.178	15.253	EPSD	CCLE	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	Q9UPN3	MACF1	P24941	CDK2	T7296	N7289S	7289	Missense	distal	-7	no	10.481	10.382	EPSD	CCLE	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	Q9UPN3	MACF1	P24941	CDK2	S7380	S7380Y	7380	Missense	central	0	yes	15.816	0.000	EPSD	CCLE	8.148	Loss
CMGC_CDK_CDK2_CDK2_ST	Q9UPN3	MACF1	P24941	CDK2	S7380	P7386L	7386	Missense	distal	6	no	15.816	15.818	EPSD	CCLE	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	Q9UPN3	MACF1	P24941	CDK2	T7383	S7380Y	7380	Missense	distal	-3	no	16.357	16.376	EPSD	CCLE	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	Q9UPN3	MACF1	P24941	CDK2	T7383	P7386L	7386	Missense	distal	3	no	16.357	15.973	EPSD	CCLE	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	Q03252	LMNB2	P24941	CDK2	T34	P38S	38	Missense	distal	4	no	14.080	14.094	EPSD	CCLE	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	Q03252	LMNB2	P24941	CDK2	S37	P38S	38	Missense	proximal	1	no	16.340	5.074	PhosphoSitePlus	CCLE	8.148	Loss
CMGC_CDK_CDK2_CDK2_ST	Q9UIF9	BAZ2A	P24941	CDK2	S135	N139K	139	Missense	distal	4	no	13.535	13.957	EPSD	CCLE	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	Q9UIF9	BAZ2A	P24941	CDK2	S1350	P1347S	1347	Missense	distal	-3	no	13.583	13.678	EPSD	CCLE	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	P22234	PAICS	P24941	CDK2	T105	A104V	104	Missense	proximal	-1	no	8.910	9.137	EPSD	CCLE	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	Q6Y7W6	GIGYF2	P24941	CDK2	S30	K37E	37	Missense	distal	7	no	13.058	13.389	PhosphoSitePlus;EPSD	CCLE	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	Q6Y7W6	GIGYF2	P24941	CDK2	S158	G152A	152	Missense	distal	-6	no	8.312	8.309	EPSD	CCLE	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	Q6Y7W6	GIGYF2	P24941	CDK2	S236	A243T	243	Missense	distal	7	no	15.266	14.577	EPSD	CCLE	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	Q6Y7W6	GIGYF2	P24941	CDK2	S273	R266Q	266	Missense	distal	-7	no	10.054	9.667	EPSD	CCLE	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	Q9NXR1	NDE1	P24941	CDK2	T191	Q186E	186	Missense	distal	-5	no	12.949	12.986	EPSD	CCLE	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	Q9NXR1	NDE1	P24941	CDK2	T215	V212L	212	Missense	distal	-3	no	13.557	13.343	EPSD	CCLE	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	Q9NXR1	NDE1	P24941	CDK2	T215	H219L	219	Missense	distal	4	no	13.557	13.906	EPSD	CCLE	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	Q9NXR1	NDE1	P24941	CDK2	S328	H329Y	329	Missense	proximal	1	no	9.306	0.566	EPSD	CCLE	8.148	Loss
CMGC_CDK_CDK2_CDK2_ST	Q9NXR1	NDE1	P24941	CDK2	S333	H329Y	329	Missense	distal	-4	no	13.283	14.353	EPSD	CCLE	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	Q8WUM0	NUP133	P24941	CDK2	T63	M67K	67	Missense	distal	4	no	16.237	17.059	EPSD	CCLE	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	P46013	MKI67	P24941	CDK2	S460	L461H	461	Missense	proximal	1	no	6.923	9.986	EPSD	CCLE	8.148	Gain
CMGC_CDK_CDK2_CDK2_ST	P46013	MKI67	P24941	CDK2	T543	P545H	545	Missense	proximal	2	no	11.508	11.586	EPSD	CCLE	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	P46013	MKI67	P24941	CDK2	S648	S648I	648	Missense	central	0	yes	8.961	0.000	EPSD	CCLE	8.148	Loss
CMGC_CDK_CDK2_CDK2_ST	P46013	MKI67	P24941	CDK2	S648	S644F	644	Missense	distal	-4	no	8.961	7.999	EPSD	CCLE	8.148	Loss
CMGC_CDK_CDK2_CDK2_ST	P46013	MKI67	P24941	CDK2	S648	M641L	641	Missense	distal	-7	no	8.961	8.465	EPSD	CCLE	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	P46013	MKI67	P24941	CDK2	T761	A756V	756	Missense	distal	-5	no	15.206	15.212	EPSD	CCLE	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	P46013	MKI67	P24941	CDK2	T1017	T1019S	1019	Missense	proximal	2	no	14.787	15.031	EPSD	CCLE	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	P46013	MKI67	P24941	CDK2	S1071	P1072L	1072	Missense	proximal	1	no	12.202	2.381	EPSD	CCLE	8.148	Loss
CMGC_CDK_CDK2_CDK2_ST	P46013	MKI67	P24941	CDK2	T1449	H1454Y	1454	Missense	distal	5	no	8.370	8.365	EPSD	CCLE	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	P46013	MKI67	P24941	CDK2	T1485	V1478I	1478	Missense	distal	-7	no	8.583	8.758	EPSD	CCLE	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	P46013	MKI67	P24941	CDK2	T1503	P1498S	1498	Missense	distal	-5	no	14.340	14.296	EPSD	CCLE	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	P46013	MKI67	P24941	CDK2	T1531	S1533L	1533	Missense	proximal	2	no	12.626	12.452	EPSD	CCLE	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	P46013	MKI67	P24941	CDK2	T1531	T1531A	1531	Missense	central	0	yes	12.626	0.000	EPSD	CCLE	8.148	Loss
CMGC_CDK_CDK2_CDK2_ST	P46013	MKI67	P24941	CDK2	T1540	S1533L	1533	Missense	distal	-7	no	10.897	11.083	EPSD	CCLE	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	P46013	MKI67	P24941	CDK2	T1923	E1926Q	1926	Missense	distal	3	no	13.948	13.302	EPSD	CCLE	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	P46013	MKI67	P24941	CDK2	T2203	Q2202H	2202	Missense	proximal	-1	no	8.173	8.600	EPSD	CCLE	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	P46013	MKI67	P24941	CDK2	T2203	E2199Q	2199	Missense	distal	-4	no	8.173	7.725	EPSD	CCLE	8.148	Loss
CMGC_CDK_CDK2_CDK2_ST	P46013	MKI67	P24941	CDK2	T2212	E2214Q	2214	Missense	proximal	2	no	10.202	10.165	EPSD	CCLE	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	P46013	MKI67	P24941	CDK2	T2259	R2258P	2258	Missense	proximal	-1	no	14.371	13.801	EPSD	CCLE	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	P46013	MKI67	P24941	CDK2	T2285	V2287M	2287	Missense	proximal	2	no	11.870	11.959	EPSD	CCLE	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	P46013	MKI67	P24941	CDK2	T2325	F2323L	2323	Missense	proximal	-2	no	12.538	13.427	EPSD	CCLE	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	P46013	MKI67	P24941	CDK2	T2540	L2546P	2546	Missense	distal	6	no	8.151	8.150	EPSD	CCLE	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	P46013	MKI67	P24941	CDK2	T2773	A2778V	2778	Missense	distal	5	no	13.534	13.491	EPSD	CCLE	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	P46013	MKI67	P24941	CDK2	T2781	A2778V	2778	Missense	distal	-3	no	9.210	9.411	EPSD	CCLE	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	P26358	DNMT1	P24941	CDK2	S115	R118P	118	Missense	distal	3	no	8.525	6.807	EPSD	CCLE	8.148	Loss
CMGC_CDK_CDK2_CDK2_ST	P26358	DNMT1	P24941	CDK2	T137	T137R	137	Missense	central	0	yes	16.872	0.000	EPSD	CCLE	8.148	Loss
CMGC_CDK_CDK2_CDK2_ST	P26358	DNMT1	P24941	CDK2	S227	E221V	221	Missense	distal	-6	no	9.594	9.593	EPSD	CCLE	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	P26358	DNMT1	P24941	CDK2	S288	K285Q	285	Missense	distal	-3	no	8.061	8.160	EPSD	CCLE	8.148	Gain
CMGC_CDK_CDK2_CDK2_ST	P26358	DNMT1	P24941	CDK2	T328	K335R	335	Missense	distal	7	no	13.716	14.492	EPSD	CCLE	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	P26358	DNMT1	P24941	CDK2	T328	T333M	333	Missense	distal	5	no	13.716	14.049	EPSD	CCLE	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	P26358	DNMT1	P24941	CDK2	S878	A874T	874	Missense	distal	-4	no	17.043	17.268	EPSD	CCLE	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	P26358	DNMT1	P24941	CDK2	S1105	P1099S	1099	Missense	distal	-6	no	16.630	16.629	EPSD	CCLE	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	Q2NL82	TSR1	P24941	CDK2	T490	P485S	485	Missense	distal	-5	no	15.273	15.229	PhosphoSitePlus	CCLE	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	Q2NL82	TSR1	P24941	CDK2	S512	N519S	519	Missense	distal	7	no	12.985	12.927	EPSD	CCLE	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	Q2NL82	TSR1	P24941	CDK2	S512	F509L	509	Missense	distal	-3	no	12.985	12.728	EPSD	CCLE	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	P22674	CCNO	P24941	CDK2	S81	G85C	85	Missense	distal	4	no	16.985	16.358	PhosphoSitePlus	CCLE	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	Q9P2B4	CTTNBP2NL	P24941	CDK2	S285	Q282L	282	Missense	distal	-3	no	13.740	13.611	EPSD	CCLE	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	O75616	ERAL1	P24941	CDK2	S53	R56H	56	Missense	distal	3	no	8.647	7.951	EPSD	CCLE	8.148	Loss
CMGC_CDK_CDK2_CDK2_ST	O75616	ERAL1	P24941	CDK2	S216	R212W	212	Missense	distal	-4	no	11.150	10.393	EPSD	CCLE	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	P38398	BRCA1	P24941	CDK2	T967	L973F	973	Missense	distal	6	no	17.308	17.289	EPSD	CCLE	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	P38398	BRCA1	P24941	CDK2	T1561	D1557N	1557	Missense	distal	-4	no	13.897	13.508	EPSD	CCLE	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	P38398	BRCA1	P24941	CDK2	S1613	E1609D	1609	Missense	distal	-4	no	13.553	13.850	EPSD	CCLE	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	Q9H1E3	NUCKS1	P24941	CDK2	S223	P224L	224	Missense	proximal	1	no	15.342	5.521	EPSD	CCLE	8.148	Loss
CMGC_CDK_CDK2_CDK2_ST	Q9H1E3	NUCKS1	P24941	CDK2	S229	G233V	233	Missense	distal	4	no	8.143	8.490	EPSD	CCLE	8.148	Gain
CMGC_CDK_CDK2_CDK2_ST	Q9H1E3	NUCKS1	P24941	CDK2	S229	P224L	224	Missense	distal	-5	no	8.143	8.154	EPSD	CCLE	8.148	Gain
CMGC_CDK_CDK2_CDK2_ST	Q9UQ80	PA2G4	P24941	CDK2	T180	I182V	182	Missense	proximal	2	no	13.872	14.017	EPSD	CCLE	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	O75152	ZC3H11A	P24941	CDK2	T579	V585I	585	Missense	distal	6	no	13.273	13.275	EPSD	CCLE	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	O75152	ZC3H11A	P24941	CDK2	T579	V585L	585	Missense	distal	6	no	13.273	13.276	EPSD	CCLE	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	O75152	ZC3H11A	P24941	CDK2	T579	A586V	586	Missense	distal	7	no	13.273	13.147	EPSD	CCLE	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	O75152	ZC3H11A	P24941	CDK2	S738	T731I	731	Missense	distal	-7	no	13.445	13.642	EPSD	CCLE	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	Q8IXJ6	SIRT2	P24941	CDK2	S53	S46F	46	Missense	distal	-7	no	7.949	8.500	EPSD	CCLE	8.148	Gain
CMGC_CDK_CDK2_CDK2_ST	Q9P270	SLAIN2	P24941	CDK2	S48	G42V	42	Missense	distal	-6	no	16.198	16.197	PhosphoSitePlus	CCLE	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	Q9P270	SLAIN2	P24941	CDK2	S48	P49R	49	Missense	proximal	1	no	16.198	6.399	PhosphoSitePlus	CCLE	8.148	Loss
CMGC_CDK_CDK2_CDK2_ST	Q9P270	SLAIN2	P24941	CDK2	S63	P57S	57	Missense	distal	-6	no	14.482	14.481	EPSD	CCLE	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	Q9P270	SLAIN2	P24941	CDK2	S63	S63F	63	Missense	central	0	yes	14.482	0.000	EPSD	CCLE	8.148	Loss
CMGC_CDK_CDK2_CDK2_ST	Q9P270	SLAIN2	P24941	CDK2	S81	R84G	84	Missense	distal	3	no	10.180	8.360	EPSD	CCLE	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	Q9P270	SLAIN2	P24941	CDK2	S81	R84S	84	Missense	distal	3	no	10.180	8.495	EPSD	CCLE	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	Q9P270	SLAIN2	P24941	CDK2	S81	S87R	87	Missense	distal	6	no	10.180	10.162	EPSD	CCLE	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	Q9P270	SLAIN2	P24941	CDK2	S357	R363H	363	Missense	distal	6	no	12.354	12.365	EPSD	CCLE	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	Q9P270	SLAIN2	P24941	CDK2	S361	R363H	363	Missense	proximal	2	no	13.096	13.015	EPSD	CCLE	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	Q9P270	SLAIN2	P24941	CDK2	S366	R363H	363	Missense	distal	-3	no	17.857	17.815	EPSD	CCLE	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	Q9P270	SLAIN2	P24941	CDK2	S462	S467Y	467	Missense	distal	5	no	13.727	13.902	EPSD	CCLE	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	Q9P270	SLAIN2	P24941	CDK2	S467	S467Y	467	Missense	central	0	yes	13.708	0.000	EPSD	CCLE	8.148	Loss
CMGC_CDK_CDK2_CDK2_ST	Q13309	SKP2	P24941	CDK2	S179	V183G	183	Missense	distal	4	no	17.503	17.156	EPSD	CCLE	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	P04637	TP53	P24941	CDK2	S33	E28Q	28	Missense	distal	-5	no	15.549	15.512	EPSD	CCLE	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	Q9C0D5	TANC1	P24941	CDK2	S29	E27Q	27	Missense	proximal	-2	no	12.404	12.952	EPSD	CCLE	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	Q9C0D5	TANC1	P24941	CDK2	S207	N205S	205	Missense	proximal	-2	no	11.520	12.212	EPSD	CCLE	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	Q9C0D5	TANC1	P24941	CDK2	T284	L285P	285	Missense	proximal	1	no	3.572	13.393	EPSD	CCLE	8.148	Gain
CMGC_CDK_CDK2_CDK2_ST	Q9C0D5	TANC1	P24941	CDK2	T1721	P1718L	1718	Missense	distal	-3	no	10.690	10.619	EPSD	CCLE	8.148	Down-regulation
CMGC_CDK_CDK2_CDK2_ST	Q9C0D5	TANC1	P24941	CDK2	T1721	R1719H	1719	Missense	proximal	-2	no	10.690	10.916	EPSD	CCLE	8.148	Up-regulation
CMGC_CDK_CDK2_CDK2_ST	Q5JTV8	TOR1AIP1	P24941	CDK2	T20	W15C	15	Missense	distal	-5	no	12.521	12.467	EPSD	CCLE	8.148	Down-regulation
Atypical_Alpha_eEF2K_EEF2K_ST	P13639	EEF2	O00418	EEF2K	T54	R60Q	60	Missense	distal	6	no	88.276	87.983	EPSD	CCLE	53.998	Down-regulation
Atypical_Alpha_eEF2K_EEF2K_ST	P13639	EEF2	O00418	EEF2K	T57	R60Q	60	Missense	distal	3	no	90.548	80.538	PhosphoSitePlus	CCLE	53.998	Down-regulation
Atypical_Alpha_eEF2K_EEF2K_ST	P13639	EEF2	O00418	EEF2K	T59	R60Q	60	Missense	proximal	1	no	87.039	84.813	EPSD	CCLE	53.998	Down-regulation
Atypical_Alpha_eEF2K_EEF2K_ST	O00418	EEF2K	O00418	EEF2K	T353	S359C	359	Missense	distal	6	no	92.253	89.016	EPSD;PhosphoSitePlus	CCLE	53.998	Down-regulation
Atypical_Alpha_eEF2K_EEF2K_ST	O00418	EEF2K	O00418	EEF2K	S366	S359C	359	Missense	distal	-7	no	100.807	84.671	EPSD;PhosphoSitePlus	CCLE	53.998	Down-regulation
Atypical_Alpha_eEF2K_EEF2K_ST	O00418	EEF2K	O00418	EEF2K	S464	E458G	458	Missense	distal	-6	no	53.420	54.184	EPSD	CCLE	53.998	Gain
AGC_PKG_PRKG1_ST	P50552	VASP	Q13976	PRKG1	T278	T278M	278	Missense	central	0	yes	9.874	0.000	EPSD;PhosphoSitePlus	CCLE	7.092	Loss
AGC_PKG_PRKG1_ST	P50552	VASP	Q13976	PRKG1	S322	S324C	324	Missense	proximal	2	no	11.110	11.030	EPSD	CCLE	7.092	Down-regulation
AGC_PKG_PRKG1_ST	P50552	VASP	Q13976	PRKG1	S323	S324C	324	Missense	proximal	1	no	8.265	7.991	EPSD	CCLE	7.092	Down-regulation
AGC_PKG_PRKG1_ST	P43694	GATA4	Q13976	PRKG1	S262	K256E	256	Missense	distal	-6	no	14.320	13.840	PhosphoSitePlus	CCLE	7.092	Down-regulation
AGC_PKG_PRKG1_ST	P43694	GATA4	Q13976	PRKG1	S262	S264F	264	Missense	proximal	2	no	14.320	14.243	PhosphoSitePlus	CCLE	7.092	Down-regulation
AGC_PKG_PRKG1_ST	P11831	SRF	Q13976	PRKG1	S16	S21N	21	Missense	distal	5	no	9.131	9.098	EPSD	CCLE	7.092	Down-regulation
AGC_PKG_PRKG1_ST	P11831	SRF	Q13976	PRKG1	T27	S21N	21	Missense	distal	-6	no	8.826	8.545	EPSD	CCLE	7.092	Down-regulation
AGC_PKG_PRKG1_ST	P11831	SRF	Q13976	PRKG1	S237	R235I	235	Missense	proximal	-2	no	10.171	4.166	EPSD	CCLE	7.092	Loss
AGC_PKG_PRKG1_ST	P21731	TBXA2R	Q13976	PRKG1	S324	R326L	326	Missense	proximal	2	no	11.181	11.050	EPSD	CCLE	7.092	Down-regulation
AGC_PKG_PRKG1_ST	P21731	TBXA2R	Q13976	PRKG1	S324	S324G	324	Missense	central	0	yes	11.181	0.000	EPSD	CCLE	7.092	Loss
AGC_PKG_PRKG1_ST	P21731	TBXA2R	Q13976	PRKG1	S329	L336F	336	Missense	distal	7	no	11.239	11.331	EPSD	CCLE	7.092	Up-regulation
AGC_PKG_PRKG1_ST	P21731	TBXA2R	Q13976	PRKG1	S329	R326L	326	Missense	distal	-3	no	11.239	4.095	EPSD	CCLE	7.092	Loss
AGC_PKG_PRKG1_ST	P21731	TBXA2R	Q13976	PRKG1	S329	S324G	324	Missense	distal	-5	no	11.239	11.325	EPSD	CCLE	7.092	Up-regulation
AGC_PKG_PRKG1_ST	P21731	TBXA2R	Q13976	PRKG1	S331	L336F	336	Missense	distal	5	no	9.685	9.754	EPSD;PhosphoSitePlus	CCLE	7.092	Up-regulation
AGC_PKG_PRKG1_ST	P21731	TBXA2R	Q13976	PRKG1	S331	R326L	326	Missense	distal	-5	no	9.685	10.062	EPSD;PhosphoSitePlus	CCLE	7.092	Up-regulation
AGC_PKG_PRKG1_ST	P21731	TBXA2R	Q13976	PRKG1	S331	S324G	324	Missense	distal	-7	no	9.685	9.167	EPSD;PhosphoSitePlus	CCLE	7.092	Down-regulation
AGC_PKG_PRKG1_ST	Q9Y210	TRPC6	Q13976	PRKG1	S13	G17D	17	Missense	distal	4	no	13.571	13.594	EPSD	CCLE	7.092	Up-regulation
AGC_PKG_PRKG1_ST	Q9Y210	TRPC6	Q13976	PRKG1	S14	G17D	17	Missense	distal	3	no	12.504	12.546	EPSD	CCLE	7.092	Up-regulation
AGC_PKG_PRKG1_ST	Q9Y210	TRPC6	Q13976	PRKG1	T70	T70R	70	Missense	central	0	yes	12.250	0.000	PhosphoSitePlus;EPSD	CCLE	7.092	Loss
AGC_PKG_PRKG1_ST	P35367	HRH1	Q13976	PRKG1	T142	T140A	140	Missense	proximal	-2	no	7.063	7.200	EPSD	CCLE	7.092	Gain
AGC_PKG_PRKG1_ST	P35367	HRH1	Q13976	PRKG1	S363	T366I	366	Missense	distal	3	no	10.249	10.577	EPSD	CCLE	7.092	Up-regulation
AGC_PKG_PRKG1_ST	Q9Y613	FHOD1	Q13976	PRKG1	S874	L877P	877	Missense	distal	3	no	8.367	8.249	EPSD	CCLE	7.092	Down-regulation
AGC_PKG_PRKG1_ST	Q9Y613	FHOD1	Q13976	PRKG1	S1131	R1128H	1128	Missense	distal	-3	no	11.398	5.331	PhosphoSitePlus	CCLE	7.092	Loss
AGC_PKG_PRKG1_ST	P78347	GTF2I	Q13976	PRKG1	S412	T413A	413	Missense	proximal	1	no	13.979	14.017	EPSD;PhosphoSitePlus	CCLE	7.092	Up-regulation
AGC_PKG_PRKG1_ST	P78347	GTF2I	Q13976	PRKG1	S517	G520E	520	Missense	distal	3	no	8.811	8.838	EPSD	CCLE	7.092	Up-regulation
AGC_PKG_PRKG1_ST	P78347	GTF2I	Q13976	PRKG1	T622	G615R	615	Missense	distal	-7	no	7.948	9.097	EPSD	CCLE	7.092	Up-regulation
AGC_PKG_PRKG1_ST	P78347	GTF2I	Q13976	PRKG1	T622	S620R	620	Missense	proximal	-2	no	7.948	11.356	EPSD	CCLE	7.092	Up-regulation
AGC_PKG_PRKG1_ST	P78347	GTF2I	Q13976	PRKG1	S784	R781Q	781	Missense	distal	-3	no	13.495	9.660	PhosphoSitePlus;EPSD	CCLE	7.092	Down-regulation
AGC_PKG_PRKG1_ST	P78347	GTF2I	Q13976	PRKG1	S784	P789L	789	Missense	distal	5	no	13.495	13.451	PhosphoSitePlus;EPSD	CCLE	7.092	Down-regulation
AGC_PKG_PRKG1_ST	P78347	GTF2I	Q13976	PRKG1	T785	R781Q	781	Missense	distal	-4	no	7.445	7.050	EPSD	CCLE	7.092	Loss
AGC_PKG_PRKG1_ST	P78347	GTF2I	Q13976	PRKG1	T785	P789L	789	Missense	distal	4	no	7.445	7.545	EPSD	CCLE	7.092	Up-regulation
AGC_PKG_PRKG1_ST	Q96D31	ORAI1	Q13976	PRKG1	S13	S13C	13	Missense	central	0	yes	8.488	0.000	EPSD	CCLE	7.092	Loss
AGC_PKG_PRKG1_ST	Q96D31	ORAI1	Q13976	PRKG1	S13	L16F	16	Missense	distal	3	no	8.488	8.302	EPSD	CCLE	7.092	Down-regulation
AGC_PKG_PRKG1_ST	Q96D31	ORAI1	Q13976	PRKG1	S30	R29Q	29	Missense	proximal	-1	no	8.529	8.464	EPSD	CCLE	7.092	Down-regulation
AGC_PKG_PRKG1_ST	Q96D31	ORAI1	Q13976	PRKG1	S30	S34R	34	Missense	distal	4	no	8.529	8.493	EPSD	CCLE	7.092	Down-regulation
AGC_PKG_PRKG1_ST	Q96D31	ORAI1	Q13976	PRKG1	S30	G35R	35	Missense	distal	5	no	8.529	8.605	EPSD	CCLE	7.092	Up-regulation
AGC_PKG_PRKG1_ST	Q96D31	ORAI1	Q13976	PRKG1	S30	D36N	36	Missense	distal	6	no	8.529	8.439	EPSD	CCLE	7.092	Down-regulation
AGC_PKG_PRKG1_ST	Q96D31	ORAI1	Q13976	PRKG1	S34	R29Q	29	Missense	distal	-5	no	14.447	14.568	PhosphoSitePlus	CCLE	7.092	Up-regulation
AGC_PKG_PRKG1_ST	Q96D31	ORAI1	Q13976	PRKG1	S34	S34R	34	Missense	central	0	yes	14.447	0.000	PhosphoSitePlus	CCLE	7.092	Loss
AGC_PKG_PRKG1_ST	Q96D31	ORAI1	Q13976	PRKG1	S34	G35R	35	Missense	proximal	1	no	14.447	14.811	PhosphoSitePlus	CCLE	7.092	Up-regulation
AGC_PKG_PRKG1_ST	Q96D31	ORAI1	Q13976	PRKG1	S34	D36N	36	Missense	proximal	2	no	14.447	14.470	PhosphoSitePlus	CCLE	7.092	Up-regulation
AGC_PKG_PRKG1_ST	Q14847	LASP1	Q13976	PRKG1	S61	Y57H	57	Missense	distal	-4	no	7.442	7.595	EPSD	CCLE	7.092	Up-regulation
AGC_PKG_PRKG1_ST	Q14847	LASP1	Q13976	PRKG1	S61	S61P	61	Missense	central	0	yes	7.442	0.000	EPSD	CCLE	7.092	Loss
AGC_PKG_PRKG1_ST	Q14847	LASP1	Q13976	PRKG1	S99	E106Q	106	Missense	distal	7	no	7.566	7.651	EPSD	CCLE	7.092	Up-regulation
AGC_PKG_PRKG1_ST	Q684P5	RAP1GAP2	Q13976	PRKG1	S57	L63P	63	Missense	distal	6	no	8.283	8.155	EPSD	CCLE	7.092	Down-regulation
AGC_PKG_PRKG1_ST	Q684P5	RAP1GAP2	Q13976	PRKG1	S505	A500P	500	Missense	distal	-5	no	9.649	9.765	EPSD	CCLE	7.092	Up-regulation
AGC_PKG_PRKG1_ST	Q684P5	RAP1GAP2	Q13976	PRKG1	S507	A500P	500	Missense	distal	-7	no	9.266	8.658	EPSD	CCLE	7.092	Down-regulation
AGC_PKG_PRKG1_ST	Q684P5	RAP1GAP2	Q13976	PRKG1	S564	F567S	567	Missense	distal	3	no	13.411	13.228	EPSD	CCLE	7.092	Down-regulation
AGC_PKG_PRKG1_ST	Q684P5	RAP1GAP2	Q13976	PRKG1	S638	G631D	631	Missense	distal	-7	no	7.581	7.035	EPSD	CCLE	7.092	Loss
AGC_PKG_PRKG1_ST	Q8WZ42	TTN	Q13976	PRKG1	T330	T330A	330	Missense	central	0	yes	7.819	0.000	EPSD	CCLE	7.092	Loss
AGC_PKG_PRKG1_ST	Q8WZ42	TTN	Q13976	PRKG1	S540	S540F	540	Missense	central	0	yes	8.164	0.000	EPSD	CCLE	7.092	Loss
AGC_PKG_PRKG1_ST	Q8WZ42	TTN	Q13976	PRKG1	S847	A840D	840	Missense	distal	-7	no	7.475	6.571	EPSD	CCLE	7.092	Loss
AGC_PKG_PRKG1_ST	Q8WZ42	TTN	Q13976	PRKG1	S1348	I1351V	1351	Missense	distal	3	no	7.863	7.770	EPSD	CCLE	7.092	Down-regulation
AGC_PKG_PRKG1_ST	Q8WZ42	TTN	Q13976	PRKG1	S1433	R1436K	1436	Missense	distal	3	no	9.496	9.577	EPSD	CCLE	7.092	Up-regulation
AGC_PKG_PRKG1_ST	Q8WZ42	TTN	Q13976	PRKG1	S1438	R1436K	1436	Missense	proximal	-2	no	9.145	7.668	EPSD	CCLE	7.092	Down-regulation
AGC_PKG_PRKG1_ST	Q8WZ42	TTN	Q13976	PRKG1	S2026	D2024N	2024	Missense	proximal	-2	no	5.958	7.440	EPSD	CCLE	7.092	Gain
AGC_PKG_PRKG1_ST	Q8WZ42	TTN	Q13976	PRKG1	S3122	A3124T	3124	Missense	proximal	2	no	7.720	7.713	EPSD	CCLE	7.092	Down-regulation
AGC_PKG_PRKG1_ST	Q8WZ42	TTN	Q13976	PRKG1	S4065	L4060I	4060	Missense	distal	-5	no	7.354	7.345	EPSD	CCLE	7.092	Down-regulation
AGC_PKG_PRKG1_ST	Q8WZ42	TTN	Q13976	PRKG1	S4993	N4996Y	4996	Missense	distal	3	no	7.630	7.705	EPSD	CCLE	7.092	Up-regulation
AGC_PKG_PRKG1_ST	Q8WZ42	TTN	Q13976	PRKG1	S5276	S5280F	5280	Missense	distal	4	no	7.352	7.480	EPSD	CCLE	7.092	Up-regulation
AGC_PKG_PRKG1_ST	Q8WZ42	TTN	Q13976	PRKG1	S5873	S5871R	5871	Missense	proximal	-2	no	5.905	9.313	EPSD	CCLE	7.092	Gain
AGC_PKG_PRKG1_ST	Q8WZ42	TTN	Q13976	PRKG1	S6135	Q6133E	6133	Missense	proximal	-2	no	7.965	5.930	EPSD	CCLE	7.092	Loss
AGC_PKG_PRKG1_ST	Q8WZ42	TTN	Q13976	PRKG1	S7563	G7558L	7558	Missense	distal	-5	no	9.410	9.560	EPSD	CCLE	7.092	Up-regulation
AGC_PKG_PRKG1_ST	Q8WZ42	TTN	Q13976	PRKG1	S7613	S7616N	7616	Missense	distal	3	no	8.208	8.323	EPSD	CCLE	7.092	Up-regulation
AGC_PKG_PRKG1_ST	Q8WZ42	TTN	Q13976	PRKG1	S10146	Q10151E	10151	Missense	distal	5	no	7.825	7.768	EPSD	CCLE	7.092	Down-regulation
AGC_PKG_PRKG1_ST	Q8WZ42	TTN	Q13976	PRKG1	S10146	R10147W	10147	Missense	proximal	1	no	7.825	7.255	EPSD	CCLE	7.092	Down-regulation
AGC_PKG_PRKG1_ST	Q8WZ42	TTN	Q13976	PRKG1	T10658	E10654K	10654	Missense	distal	-4	no	8.296	8.956	EPSD	CCLE	7.092	Up-regulation
AGC_PKG_PRKG1_ST	Q8WZ42	TTN	Q13976	PRKG1	S11223	E11216D	11216	Missense	distal	-7	no	7.439	7.211	EPSD	CCLE	7.092	Down-regulation
AGC_PKG_PRKG1_ST	Q8WZ42	TTN	Q13976	PRKG1	S12009	A12013S	12013	Missense	distal	4	no	7.621	7.600	EPSD	CCLE	7.092	Down-regulation
AGC_PKG_PRKG1_ST	Q8WZ42	TTN	Q13976	PRKG1	S12009	S12009L	12009	Missense	central	0	yes	7.621	0.000	EPSD	CCLE	7.092	Loss
AGC_PKG_PRKG1_ST	Q8WZ42	TTN	Q13976	PRKG1	S12900	G12907V	12907	Missense	distal	7	no	7.652	7.633	EPSD	CCLE	7.092	Down-regulation
AGC_PKG_PRKG1_ST	Q8WZ42	TTN	Q13976	PRKG1	S12900	L12895R	12895	Missense	distal	-5	no	7.652	7.276	EPSD	CCLE	7.092	Down-regulation
AGC_PKG_PRKG1_ST	Q8WZ42	TTN	Q13976	PRKG1	S12902	G12907V	12907	Missense	distal	5	no	8.760	8.749	EPSD	CCLE	7.092	Down-regulation
AGC_PKG_PRKG1_ST	Q8WZ42	TTN	Q13976	PRKG1	S12902	L12895R	12895	Missense	distal	-7	no	8.760	10.775	EPSD	CCLE	7.092	Up-regulation
AGC_PKG_PRKG1_ST	Q8WZ42	TTN	Q13976	PRKG1	S12911	G12907V	12907	Missense	distal	-4	no	7.122	6.805	EPSD	CCLE	7.092	Loss
AGC_PKG_PRKG1_ST	Q8WZ42	TTN	Q13976	PRKG1	S13113	Q13106E	13106	Missense	distal	-7	no	7.486	6.695	EPSD	CCLE	7.092	Loss
AGC_PKG_PRKG1_ST	Q8WZ42	TTN	Q13976	PRKG1	T13178	E13173K	13173	Missense	distal	-5	no	7.324	7.143	EPSD	CCLE	7.092	Down-regulation
AGC_PKG_PRKG1_ST	Q8WZ42	TTN	Q13976	PRKG1	S13380	V13374A	13374	Missense	distal	-6	no	8.750	9.087	EPSD	CCLE	7.092	Up-regulation
AGC_PKG_PRKG1_ST	Q8WZ42	TTN	Q13976	PRKG1	T14402	G14405E	14405	Missense	distal	3	no	7.281	7.309	EPSD	CCLE	7.092	Up-regulation
AGC_PKG_PRKG1_ST	Q8WZ42	TTN	Q13976	PRKG1	S15744	W15749C	15749	Missense	distal	5	no	10.204	10.234	EPSD	CCLE	7.092	Up-regulation
AGC_PKG_PRKG1_ST	Q8WZ42	TTN	Q13976	PRKG1	S16329	T16334A	16334	Missense	distal	5	no	7.660	7.650	EPSD	CCLE	7.092	Down-regulation
AGC_PKG_PRKG1_ST	Q8WZ42	TTN	Q13976	PRKG1	T16334	T16334A	16334	Missense	central	0	yes	7.497	0.000	EPSD	CCLE	7.092	Loss
AGC_PKG_PRKG1_ST	Q8WZ42	TTN	Q13976	PRKG1	S16646	W16652C	16652	Missense	distal	6	no	7.331	7.240	EPSD	CCLE	7.092	Down-regulation
AGC_PKG_PRKG1_ST	Q8WZ42	TTN	Q13976	PRKG1	S16646	T16644A	16644	Missense	proximal	-2	no	7.331	7.467	EPSD	CCLE	7.092	Up-regulation
AGC_PKG_PRKG1_ST	Q8WZ42	TTN	Q13976	PRKG1	S16647	W16652C	16652	Missense	distal	5	no	7.339	7.369	EPSD	CCLE	7.092	Up-regulation
AGC_PKG_PRKG1_ST	Q8WZ42	TTN	Q13976	PRKG1	S16647	T16644A	16644	Missense	distal	-3	no	7.339	7.926	EPSD	CCLE	7.092	Up-regulation
AGC_PKG_PRKG1_ST	Q8WZ42	TTN	Q13976	PRKG1	T16931	P16938S	16938	Missense	distal	7	no	7.054	7.156	EPSD	CCLE	7.092	Gain
AGC_PKG_PRKG1_ST	Q8WZ42	TTN	Q13976	PRKG1	S17521	A17528G	17528	Missense	distal	7	no	7.145	7.093	EPSD	CCLE	7.092	Down-regulation
AGC_PKG_PRKG1_ST	Q8WZ42	TTN	Q13976	PRKG1	S18976	W18975G	18975	Missense	proximal	-1	no	7.647	7.739	EPSD	CCLE	7.092	Up-regulation
AGC_PKG_PRKG1_ST	Q8WZ42	TTN	Q13976	PRKG1	S18976	K18969R	18969	Missense	distal	-7	no	7.647	8.113	EPSD	CCLE	7.092	Up-regulation
AGC_PKG_PRKG1_ST	Q8WZ42	TTN	Q13976	PRKG1	S19673	T19676A	19676	Missense	distal	3	no	8.573	8.606	EPSD	CCLE	7.092	Up-regulation
AGC_PKG_PRKG1_ST	Q8WZ42	TTN	Q13976	PRKG1	S19683	L19689F	19689	Missense	distal	6	no	9.216	9.043	EPSD	CCLE	7.092	Down-regulation
AGC_PKG_PRKG1_ST	Q8WZ42	TTN	Q13976	PRKG1	S19683	L19689I	19689	Missense	distal	6	no	9.216	9.184	EPSD	CCLE	7.092	Down-regulation
AGC_PKG_PRKG1_ST	Q8WZ42	TTN	Q13976	PRKG1	S19683	T19676A	19676	Missense	distal	-7	no	9.216	9.270	EPSD	CCLE	7.092	Up-regulation
AGC_PKG_PRKG1_ST	Q8WZ42	TTN	Q13976	PRKG1	S20559	V20554I	20554	Missense	distal	-5	no	9.725	9.828	EPSD	CCLE	7.092	Up-regulation
AGC_PKG_PRKG1_ST	Q8WZ42	TTN	Q13976	PRKG1	S20864	M20860I	20860	Missense	distal	-4	no	7.755	7.049	EPSD	CCLE	7.092	Loss
AGC_PKG_PRKG1_ST	Q8WZ42	TTN	Q13976	PRKG1	S22060	D22059H	22059	Missense	proximal	-1	no	7.662	7.777	EPSD	CCLE	7.092	Up-regulation
AGC_PKG_PRKG1_ST	Q8WZ42	TTN	Q13976	PRKG1	S22060	V22056D	22056	Missense	distal	-4	no	7.662	7.551	EPSD	CCLE	7.092	Down-regulation
AGC_PKG_PRKG1_ST	Q8WZ42	TTN	Q13976	PRKG1	S22275	M22278T	22278	Missense	distal	3	no	8.026	7.982	EPSD	CCLE	7.092	Down-regulation
AGC_PKG_PRKG1_ST	Q8WZ42	TTN	Q13976	PRKG1	T23555	R23552K	23552	Missense	distal	-3	no	8.643	6.285	EPSD	CCLE	7.092	Loss
AGC_PKG_PRKG1_ST	Q8WZ42	TTN	Q13976	PRKG1	T23898	V23891A	23891	Missense	distal	-7	no	8.004	8.706	EPSD	CCLE	7.092	Up-regulation
AGC_PKG_PRKG1_ST	Q8WZ42	TTN	Q13976	PRKG1	T24905	L24902P	24902	Missense	distal	-3	no	5.150	7.393	EPSD	CCLE	7.092	Gain
AGC_PKG_PRKG1_ST	Q8WZ42	TTN	Q13976	PRKG1	T25374	T25374A	25374	Missense	central	0	yes	8.716	0.000	EPSD	CCLE	7.092	Loss
AGC_PKG_PRKG1_ST	Q8WZ42	TTN	Q13976	PRKG1	S26472	R26470I	26470	Missense	proximal	-2	no	9.482	3.477	EPSD	CCLE	7.092	Loss
AGC_PKG_PRKG1_ST	Q8WZ42	TTN	Q13976	PRKG1	S26497	G26495R	26495	Missense	proximal	-2	no	5.613	9.100	EPSD	CCLE	7.092	Gain
AGC_PKG_PRKG1_ST	Q8WZ42	TTN	Q13976	PRKG1	S26629	H26636R	26636	Missense	distal	7	no	7.828	7.911	EPSD	CCLE	7.092	Up-regulation
AGC_PKG_PRKG1_ST	Q8WZ42	TTN	Q13976	PRKG1	S26629	W26632L	26632	Missense	distal	3	no	7.828	7.944	EPSD	CCLE	7.092	Up-regulation
AGC_PKG_PRKG1_ST	Q8WZ42	TTN	Q13976	PRKG1	T27183	L27190M	27190	Missense	distal	7	no	7.087	7.237	EPSD	CCLE	7.092	Gain
AGC_PKG_PRKG1_ST	Q8WZ42	TTN	Q13976	PRKG1	T28055	T28058A	28058	Missense	distal	3	no	7.562	7.594	EPSD	CCLE	7.092	Up-regulation
AGC_PKG_PRKG1_ST	Q8WZ42	TTN	Q13976	PRKG1	S28340	S28347F	28347	Missense	distal	7	no	9.517	9.442	EPSD	CCLE	7.092	Down-regulation
AGC_PKG_PRKG1_ST	Q8WZ42	TTN	Q13976	PRKG1	S28521	G28528V	28528	Missense	distal	7	no	7.355	7.336	EPSD	CCLE	7.092	Down-regulation
AGC_PKG_PRKG1_ST	Q8WZ42	TTN	Q13976	PRKG1	S28627	E28622Q	28622	Missense	distal	-5	no	8.326	8.173	EPSD	CCLE	7.092	Down-regulation
AGC_PKG_PRKG1_ST	Q8WZ42	TTN	Q13976	PRKG1	S30920	R30919C	30919	Missense	proximal	-1	no	8.644	8.442	EPSD	CCLE	7.092	Down-regulation
AGC_PKG_PRKG1_ST	Q8WZ42	TTN	Q13976	PRKG1	S31449	K31453N	31453	Missense	distal	4	no	7.134	7.210	EPSD	CCLE	7.092	Up-regulation
AGC_PKG_PRKG1_ST	Q8WZ42	TTN	Q13976	PRKG1	S31456	K31453N	31453	Missense	distal	-3	no	7.451	2.904	EPSD	CCLE	7.092	Loss
AGC_PKG_PRKG1_ST	Q8WZ42	TTN	Q13976	PRKG1	T32998	D33004N	33004	Missense	distal	6	no	11.722	11.632	EPSD	CCLE	7.092	Down-regulation
AGC_PKG_PRKG1_ST	Q8WZ42	TTN	Q13976	PRKG1	S33000	D33004N	33004	Missense	distal	4	no	10.239	10.186	EPSD	CCLE	7.092	Down-regulation
AGC_PKG_PRKG1_ST	Q8WZ42	TTN	Q13976	PRKG1	S33013	S33018Y	33018	Missense	distal	5	no	12.058	12.000	EPSD	CCLE	7.092	Down-regulation
AGC_PKG_PRKG1_ST	Q8WZ42	TTN	Q13976	PRKG1	S33013	D33016V	33016	Missense	distal	3	no	12.058	12.080	EPSD	CCLE	7.092	Up-regulation
AGC_PKG_PRKG1_ST	Q8WZ42	TTN	Q13976	PRKG1	S33071	S33065Y	33065	Missense	distal	-6	no	8.448	8.085	EPSD	CCLE	7.092	Down-regulation
AGC_PKG_PRKG1_ST	Q8WZ42	TTN	Q13976	PRKG1	S33235	E33239A	33239	Missense	distal	4	no	7.154	7.054	EPSD	CCLE	7.092	Loss
AGC_PKG_PRKG1_ST	Q8WZ42	TTN	Q13976	PRKG1	T33237	P33243L	33243	Missense	distal	6	no	7.701	7.829	EPSD	CCLE	7.092	Up-regulation
AGC_PKG_PRKG1_ST	Q8WZ42	TTN	Q13976	PRKG1	T33237	E33239A	33239	Missense	proximal	2	no	7.701	7.754	EPSD	CCLE	7.092	Up-regulation
AGC_PKG_PRKG1_ST	Q8WZ42	TTN	Q13976	PRKG1	S33245	P33243L	33243	Missense	proximal	-2	no	8.318	6.783	EPSD	CCLE	7.092	Loss
AGC_PKG_PRKG1_ST	Q8WZ42	TTN	Q13976	PRKG1	S33245	E33239A	33239	Missense	distal	-6	no	8.318	8.622	EPSD	CCLE	7.092	Up-regulation
AGC_PKG_PRKG1_ST	Q8WZ42	TTN	Q13976	PRKG1	S33247	P33243L	33243	Missense	distal	-4	no	11.582	11.232	EPSD	CCLE	7.092	Down-regulation
AGC_PKG_PRKG1_ST	Q8WZ42	TTN	Q13976	PRKG1	S33496	E33501K	33501	Missense	distal	5	no	9.482	9.545	EPSD	CCLE	7.092	Up-regulation
AGC_PKG_PRKG1_ST	Q8WZ42	TTN	Q13976	PRKG1	S33496	T33498I	33498	Missense	proximal	2	no	9.482	9.386	EPSD	CCLE	7.092	Down-regulation
AGC_PKG_PRKG1_ST	Q8WZ42	TTN	Q13976	PRKG1	S33496	M33497A	33497	Missense	proximal	1	no	9.482	9.575	EPSD	CCLE	7.092	Up-regulation
AGC_PKG_PRKG1_ST	Q8WZ42	TTN	Q13976	PRKG1	T33498	E33501K	33501	Missense	distal	3	no	7.239	7.065	EPSD	CCLE	7.092	Loss
AGC_PKG_PRKG1_ST	Q8WZ42	TTN	Q13976	PRKG1	T33498	T33498I	33498	Missense	central	0	yes	7.239	0.000	EPSD	CCLE	7.092	Loss
AGC_PKG_PRKG1_ST	Q8WZ42	TTN	Q13976	PRKG1	T33498	M33497A	33497	Missense	proximal	-1	no	7.239	7.243	EPSD	CCLE	7.092	Up-regulation
AGC_PKG_PRKG1_ST	Q8WZ42	TTN	Q13976	PRKG1	S33504	E33501K	33501	Missense	distal	-3	no	2.907	7.490	EPSD	CCLE	7.092	Gain
AGC_PKG_PRKG1_ST	Q8WZ42	TTN	Q13976	PRKG1	S33624	T33628I	33628	Missense	distal	4	no	7.698	7.895	EPSD	CCLE	7.092	Up-regulation
AGC_PKG_PRKG1_ST	Q8WZ42	TTN	Q13976	PRKG1	S34298	Q34301R	34301	Missense	distal	3	no	7.575	7.504	EPSD	CCLE	7.092	Down-regulation
AGC_PKG_PRKG1_ST	P41220	RGS2	Q13976	PRKG1	S46	Y47C	47	Missense	proximal	1	no	9.681	9.710	PhosphoSitePlus;EPSD	CCLE	7.092	Up-regulation
AGC_PKG_PRKG1_ST	P41220	RGS2	Q13976	PRKG1	S46	F48Y	48	Missense	proximal	2	no	9.681	9.666	PhosphoSitePlus;EPSD	CCLE	7.092	Down-regulation
AGC_PKG_PRKG1_ST	P48995	TRPC1	Q13976	PRKG1	T347	S340L	340	Missense	distal	-7	no	10.040	8.657	PhosphoSitePlus;EPSD	CCLE	7.092	Down-regulation
AGC_PKG_PRKG1_ST	P48995	TRPC1	Q13976	PRKG1	T347	R343Q	343	Missense	distal	-4	no	10.040	9.645	PhosphoSitePlus;EPSD	CCLE	7.092	Down-regulation
AGC_PKG_PRKG1_ST	P48995	TRPC1	Q13976	PRKG1	T347	M352I	352	Missense	distal	5	no	10.040	9.946	PhosphoSitePlus;EPSD	CCLE	7.092	Down-regulation
AGC_PKG_PRKG1_ST	Q13976	PRKG1	Q13976	PRKG1	T59	T59P	59	Missense	central	0	yes	8.128	0.000	EPSD	CCLE	7.092	Loss
AGC_PKG_PRKG1_ST	Q13976	PRKG1	Q13976	PRKG1	S65	T59P	59	Missense	distal	-6	no	8.252	8.020	PhosphoSitePlus	CCLE	7.092	Down-regulation
AGC_PKG_PRKG1_ST	Q15052	ARHGEF6	Q13976	PRKG1	S640	V645A	645	Missense	distal	5	no	12.918	12.968	EPSD	CCLE	7.092	Up-regulation
AGC_PKG_PRKG1_ST	Q15052	ARHGEF6	Q13976	PRKG1	T650	A657V	657	Missense	distal	7	no	7.923	7.852	EPSD	CCLE	7.092	Down-regulation
AGC_PKG_PRKG1_ST	Q15052	ARHGEF6	Q13976	PRKG1	T650	V645A	645	Missense	distal	-5	no	7.923	7.799	EPSD	CCLE	7.092	Down-regulation
AGC_PKG_PRKG1_ST	Q76M96	CCDC80	Q13976	PRKG1	S409	L414R	414	Missense	distal	5	no	12.972	13.111	EPSD;PhosphoSitePlus	CCLE	7.092	Up-regulation
AGC_PKG_PRKG1_ST	Q76M96	CCDC80	Q13976	PRKG1	S611	A613D	613	Missense	proximal	2	no	7.178	7.116	EPSD	CCLE	7.092	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P19634	SLC9A1	P28482	MAPK1	S693	M696L	696	Missense	distal	3	no	14.394	14.399	EPSD;PhosphoSitePlus	CCLE	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P19634	SLC9A1	P28482	MAPK1	S770	T769N	769	Missense	proximal	-1	no	8.372	8.420	EPSD;PhosphoSitePlus	CCLE	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P19634	SLC9A1	P28482	MAPK1	S771	T769N	769	Missense	proximal	-2	no	15.111	14.990	EPSD;PhosphoSitePlus	CCLE	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P11388	TOP2A	P28482	MAPK1	S387	P385A	385	Missense	proximal	-2	no	10.266	7.119	EPSD	CCLE	8.102	Loss
CMGC_MAPK_ERK1_MAPK1_ST	P11388	TOP2A	P28482	MAPK1	S1162	T1157I	1157	Missense	distal	-5	no	16.061	16.168	EPSD	CCLE	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P11388	TOP2A	P28482	MAPK1	S1164	T1157I	1157	Missense	distal	-7	no	8.463	8.449	EPSD	CCLE	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P11388	TOP2A	P28482	MAPK1	S1393	P1394R	1394	Missense	proximal	1	no	10.974	1.320	EPSD;PhosphoSitePlus	CCLE	8.102	Loss
CMGC_MAPK_ERK1_MAPK1_ST	O00562	PITPNM1	P28482	MAPK1	S300	G296V	296	Missense	distal	-4	no	13.181	13.177	EPSD	CCLE	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	O00562	PITPNM1	P28482	MAPK1	S621	A626S	626	Missense	distal	5	no	14.648	14.808	EPSD	CCLE	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P15056	BRAF	P28482	MAPK1	S76	P74A	74	Missense	proximal	-2	no	8.648	5.501	EPSD	CCLE	8.102	Loss
CMGC_MAPK_ERK1_MAPK1_ST	P15056	BRAF	P28482	MAPK1	S750	I755F	755	Missense	distal	5	no	14.197	14.317	EPSD	CCLE	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P15056	BRAF	P28482	MAPK1	T753	I755F	755	Missense	proximal	2	no	19.816	19.827	EPSD;PhosphoSitePlus	CCLE	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P04626	ERBB2	P28482	MAPK1	S1174	V1181I	1181	Missense	distal	7	no	15.036	15.301	EPSD	CCLE	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P04626	ERBB2	P28482	MAPK1	S1214	P1209L	1209	Missense	distal	-5	no	13.860	14.008	EPSD	CCLE	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P36956	SREBF1	P28482	MAPK1	S63	P69T	69	Missense	distal	6	no	17.329	17.119	EPSD	CCLE	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P36956	SREBF1	P28482	MAPK1	S63	A62V	62	Missense	proximal	-1	no	17.329	17.340	EPSD	CCLE	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P36956	SREBF1	P28482	MAPK1	T105	K108Q	108	Missense	distal	3	no	13.491	13.562	EPSD	CCLE	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P36956	SREBF1	P28482	MAPK1	T426	E422D	422	Missense	distal	-4	no	11.508	11.522	EPSD	CCLE	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P36956	SREBF1	P28482	MAPK1	S524	S520G	520	Missense	distal	-4	no	17.046	16.780	EPSD	CCLE	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P10636	MAPT	P28482	MAPK1	S68	A66V	66	Missense	proximal	-2	no	6.964	8.238	EPSD	CCLE	8.102	Gain
CMGC_MAPK_ERK1_MAPK1_ST	P10636	MAPT	P28482	MAPK1	T69	A66V	66	Missense	distal	-3	no	14.584	14.644	EPSD	CCLE	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P10636	MAPT	P28482	MAPK1	T111	G107V	107	Missense	distal	-4	no	12.736	12.732	EPSD	CCLE	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P10636	MAPT	P28482	MAPK1	S228	D221Y	221	Missense	distal	-7	no	14.224	14.192	EPSD	CCLE	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P10636	MAPT	P28482	MAPK1	S232	P234S	234	Missense	proximal	2	no	15.028	15.000	EPSD	CCLE	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P10636	MAPT	P28482	MAPK1	S238	P234S	234	Missense	distal	-4	no	15.270	15.186	EPSD	CCLE	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P10636	MAPT	P28482	MAPK1	S238	D242H	242	Missense	distal	4	no	15.270	15.202	EPSD	CCLE	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P10636	MAPT	P28482	MAPK1	T248	D242H	242	Missense	distal	-6	no	9.386	9.289	EPSD	CCLE	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P10636	MAPT	P28482	MAPK1	T248	S255N	255	Missense	distal	7	no	9.386	9.369	EPSD	CCLE	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P10636	MAPT	P28482	MAPK1	S411	K405R	405	Missense	distal	-6	no	14.042	14.065	EPSD	CCLE	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P10636	MAPT	P28482	MAPK1	S438	V442I	442	Missense	distal	4	no	19.115	19.048	EPSD	CCLE	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P10636	MAPT	P28482	MAPK1	S516	R511H	511	Missense	distal	-5	no	15.969	16.046	EPSD	CCLE	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P10636	MAPT	P28482	MAPK1	S516	G518S	518	Missense	proximal	2	no	15.969	15.923	EPSD	CCLE	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P10636	MAPT	P28482	MAPK1	S519	G518S	518	Missense	proximal	-1	no	17.679	17.690	EPSD	CCLE	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P10636	MAPT	P28482	MAPK1	S519	R526L	526	Missense	distal	7	no	17.679	17.964	EPSD	CCLE	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P10636	MAPT	P28482	MAPK1	T522	G518S	518	Missense	distal	-4	no	17.162	17.428	EPSD	CCLE	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P10636	MAPT	P28482	MAPK1	T522	R526L	526	Missense	distal	4	no	17.162	17.075	EPSD	CCLE	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P10636	MAPT	P28482	MAPK1	T529	R526L	526	Missense	distal	-3	no	14.924	14.560	EPSD	CCLE	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P10636	MAPT	P28482	MAPK1	S552	R559H	559	Missense	distal	7	no	15.339	15.559	EPSD	CCLE	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P10636	MAPT	P28482	MAPK1	T562	R559H	559	Missense	distal	-3	no	8.104	7.774	EPSD	CCLE	8.102	Loss
CMGC_MAPK_ERK1_MAPK1_ST	P10636	MAPT	P28482	MAPK1	S713	G706V	706	Missense	distal	-7	no	15.734	15.733	EPSD	CCLE	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P10636	MAPT	P28482	MAPK1	S713	S717C	717	Missense	distal	4	no	15.734	15.452	EPSD	CCLE	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P10636	MAPT	P28482	MAPK1	S721	S717C	717	Missense	distal	-4	no	13.576	12.933	EPSD	CCLE	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P10636	MAPT	P28482	MAPK1	S721	S721C	721	Missense	central	0	yes	13.576	0.000	EPSD	CCLE	8.102	Loss
CMGC_MAPK_ERK1_MAPK1_ST	P10636	MAPT	P28482	MAPK1	S721	H724R	724	Missense	distal	3	no	13.576	13.534	EPSD	CCLE	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P10636	MAPT	P28482	MAPK1	S739	Q741K	741	Missense	proximal	2	no	18.678	18.788	EPSD	CCLE	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P10636	MAPT	P28482	MAPK1	T744	Q741K	741	Missense	distal	-3	no	8.265	8.304	EPSD	CCLE	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q13541	EIF4EBP1	P28482	MAPK1	T18	R19C	19	Missense	proximal	1	no	9.934	6.140	EPSD	CCLE	8.102	Loss
CMGC_MAPK_ERK1_MAPK1_ST	Q13541	EIF4EBP1	P28482	MAPK1	S65	P66H	66	Missense	proximal	1	no	13.530	5.706	PhosphoSitePlus;EPSD	CCLE	8.102	Loss
CMGC_MAPK_ERK1_MAPK1_ST	Q13541	EIF4EBP1	P28482	MAPK1	T70	P66H	66	Missense	distal	-4	no	14.934	14.693	EPSD;PhosphoSitePlus	CCLE	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q13541	EIF4EBP1	P28482	MAPK1	S96	R99C	99	Missense	distal	3	no	8.499	8.626	EPSD	CCLE	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q13541	EIF4EBP1	P28482	MAPK1	S101	R99C	99	Missense	proximal	-2	no	15.740	13.792	EPSD	CCLE	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P49715	CEBPA	P28482	MAPK1	T230	P237T	237	Missense	distal	7	no	14.607	14.770	EPSD	CCLE	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P49715	CEBPA	P28482	MAPK1	S234	P237T	237	Missense	distal	3	no	16.247	16.309	EPSD	CCLE	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P50548	ERF	P28482	MAPK1	T3	P4A	4	Missense	proximal	1	no	12.254	4.624	EPSD	CCLE	8.102	Loss
CMGC_MAPK_ERK1_MAPK1_ST	P50548	ERF	P28482	MAPK1	T456	R458H	458	Missense	proximal	2	no	13.659	13.416	EPSD	CCLE	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P50548	ERF	P28482	MAPK1	T456	G451V	451	Missense	distal	-5	no	13.659	13.688	EPSD	CCLE	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P50548	ERF	P28482	MAPK1	T538	H545Y	545	Missense	distal	7	no	7.934	8.229	EPSD	CCLE	8.102	Gain
CMGC_MAPK_ERK1_MAPK1_ST	P50548	ERF	P28482	MAPK1	S542	H545Y	545	Missense	distal	3	no	8.178	8.216	EPSD	CCLE	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P49790	NUP153	P28482	MAPK1	T369	I375V	375	Missense	distal	6	no	16.319	16.771	EPSD;PhosphoSitePlus	CCLE	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P49790	NUP153	P28482	MAPK1	S374	I375V	375	Missense	proximal	1	no	8.568	8.846	EPSD	CCLE	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P49790	NUP153	P28482	MAPK1	T413	N411K	411	Missense	proximal	-2	no	13.522	13.922	EPSD;PhosphoSitePlus	CCLE	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P49790	NUP153	P28482	MAPK1	S619	S624Y	624	Missense	distal	5	no	13.227	12.938	EPSD	CCLE	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P49790	NUP153	P28482	MAPK1	S687	K685T	685	Missense	proximal	-2	no	12.931	12.651	EPSD	CCLE	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P49790	NUP153	P28482	MAPK1	T699	S703R	703	Missense	distal	4	no	16.577	16.554	EPSD	CCLE	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q16690	DUSP5	P28482	MAPK1	T321	N323S	323	Missense	proximal	2	no	15.882	15.930	EPSD;PhosphoSitePlus	CCLE	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P35568	IRS1	P28482	MAPK1	S295	R302Q	302	Missense	distal	7	no	9.800	9.915	EPSD	CCLE	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P35568	IRS1	P28482	MAPK1	S312	A314D	314	Missense	proximal	2	no	12.828	12.942	EPSD	CCLE	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P35568	IRS1	P28482	MAPK1	S402	T403P	403	Missense	proximal	1	no	4.192	12.690	EPSD	CCLE	8.102	Gain
CMGC_MAPK_ERK1_MAPK1_ST	P35568	IRS1	P28482	MAPK1	S531	P532S	532	Missense	proximal	1	no	13.822	4.427	EPSD	CCLE	8.102	Loss
CMGC_MAPK_ERK1_MAPK1_ST	P35568	IRS1	P28482	MAPK1	S672	P679R	679	Missense	distal	7	no	13.704	13.718	EPSD	CCLE	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P35568	IRS1	P28482	MAPK1	S736	V738M	738	Missense	proximal	2	no	13.268	13.130	EPSD	CCLE	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P35568	IRS1	P28482	MAPK1	S745	S747A	747	Missense	proximal	2	no	12.472	12.370	EPSD	CCLE	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P35568	IRS1	P28482	MAPK1	S745	V738M	738	Missense	distal	-7	no	12.472	12.469	EPSD	CCLE	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P35568	IRS1	P28482	MAPK1	T793	L791P	791	Missense	proximal	-2	no	6.344	8.261	EPSD	CCLE	8.102	Gain
CMGC_MAPK_ERK1_MAPK1_ST	P35568	IRS1	P28482	MAPK1	T1107	S1105F	1105	Missense	proximal	-2	no	12.379	12.573	EPSD	CCLE	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P35568	IRS1	P28482	MAPK1	S1143	E1136K	1136	Missense	distal	-7	no	8.732	8.725	EPSD	CCLE	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P35568	IRS1	P28482	MAPK1	S1145	R1152I	1152	Missense	distal	7	no	7.592	8.137	EPSD	CCLE	8.102	Gain
CMGC_MAPK_ERK1_MAPK1_ST	P49023	PXN	P28482	MAPK1	S178	S178N	178	Missense	central	0	yes	15.145	0.000	EPSD	CCLE	8.102	Loss
CMGC_MAPK_ERK1_MAPK1_ST	P49023	PXN	P28482	MAPK1	S230	V237M	237	Missense	distal	7	no	11.912	11.989	EPSD	CCLE	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P49023	PXN	P28482	MAPK1	S244	E241K	241	Missense	distal	-3	no	10.500	10.422	EPSD	CCLE	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P49023	PXN	P28482	MAPK1	S244	V237M	237	Missense	distal	-7	no	10.500	10.498	EPSD	CCLE	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P14618	PKM	P28482	MAPK1	S420	V417M	417	Missense	distal	-3	no	12.118	11.988	EPSD	CCLE	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q15418	RPS6KA1	P28482	MAPK1	S54	A52P	52	Missense	proximal	-2	no	4.993	8.140	EPSD	CCLE	8.102	Gain
CMGC_MAPK_ERK1_MAPK1_ST	Q15418	RPS6KA1	P28482	MAPK1	T621	E624V	624	Missense	distal	3	no	10.629	10.696	EPSD	CCLE	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q15418	RPS6KA1	P28482	MAPK1	T711	N706S	706	Missense	distal	-5	no	13.769	13.818	EPSD	CCLE	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q15418	RPS6KA1	P28482	MAPK1	S732	P731S	731	Missense	proximal	-1	no	8.261	8.217	EPSD	CCLE	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q15418	RPS6KA1	P28482	MAPK1	T733	P731S	731	Missense	proximal	-2	no	8.973	6.139	EPSD	CCLE	8.102	Loss
CMGC_MAPK_ERK1_MAPK1_ST	Q09472	EP300	P28482	MAPK1	S90	M95T	95	Missense	distal	5	no	13.019	13.150	EPSD	CCLE	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q09472	EP300	P28482	MAPK1	S112	A105T	105	Missense	distal	-7	no	13.300	13.285	EPSD	CCLE	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q09472	EP300	P28482	MAPK1	S285	V279I	279	Missense	distal	-6	no	13.630	13.589	EPSD	CCLE	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q09472	EP300	P28482	MAPK1	S285	S281T	281	Missense	distal	-4	no	13.630	13.401	EPSD	CCLE	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q09472	EP300	P28482	MAPK1	T317	G322V	322	Missense	distal	5	no	14.325	14.201	EPSD;PhosphoSitePlus	CCLE	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q09472	EP300	P28482	MAPK1	T885	R883G	883	Missense	proximal	-2	no	15.433	14.057	EPSD	CCLE	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q09472	EP300	P28482	MAPK1	T885	P888S	888	Missense	distal	3	no	15.433	15.502	EPSD	CCLE	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q09472	EP300	P28482	MAPK1	T887	R883G	883	Missense	distal	-4	no	12.313	12.052	EPSD	CCLE	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q09472	EP300	P28482	MAPK1	T887	P888S	888	Missense	proximal	1	no	12.313	2.918	EPSD	CCLE	8.102	Loss
CMGC_MAPK_ERK1_MAPK1_ST	Q09472	EP300	P28482	MAPK1	S1318	Q1313E	1313	Missense	distal	-5	no	8.168	8.068	EPSD	CCLE	8.102	Loss
CMGC_MAPK_ERK1_MAPK1_ST	Q09472	EP300	P28482	MAPK1	S1726	A1721V	1721	Missense	distal	-5	no	15.158	15.129	EPSD	CCLE	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q09472	EP300	P28482	MAPK1	S1849	P1855L	1855	Missense	distal	6	no	13.372	12.966	EPSD	CCLE	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q09472	EP300	P28482	MAPK1	T1851	P1855L	1855	Missense	distal	4	no	12.194	12.073	EPSD	CCLE	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q09472	EP300	P28482	MAPK1	T1854	P1855L	1855	Missense	proximal	1	no	15.410	6.600	EPSD	CCLE	8.102	Loss
CMGC_MAPK_ERK1_MAPK1_ST	Q09472	EP300	P28482	MAPK1	T1857	P1855L	1855	Missense	proximal	-2	no	17.476	15.559	EPSD	CCLE	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q09472	EP300	P28482	MAPK1	T1906	A1902V	1902	Missense	distal	-4	no	11.793	11.733	EPSD	CCLE	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q09472	EP300	P28482	MAPK1	T1909	A1902V	1902	Missense	distal	-7	no	15.192	15.176	EPSD	CCLE	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q09472	EP300	P28482	MAPK1	S2309	Q2306E	2306	Missense	distal	-3	no	12.769	12.886	EPSD	CCLE	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q09472	EP300	P28482	MAPK1	S2309	R2308H	2308	Missense	proximal	-1	no	12.769	12.746	EPSD	CCLE	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q09472	EP300	P28482	MAPK1	S2315	R2308H	2308	Missense	distal	-7	no	15.570	15.559	PhosphoSitePlus;EPSD	CCLE	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P07101	TH	P28482	MAPK1	S62	R68H	68	Missense	distal	6	no	16.623	16.424	EPSD;PhosphoSitePlus	CCLE	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P07101	TH	P28482	MAPK1	S62	R68C	68	Missense	distal	6	no	16.623	15.862	EPSD;PhosphoSitePlus	CCLE	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P07101	TH	P28482	MAPK1	S62	S55F	55	Missense	distal	-7	no	16.623	16.602	EPSD;PhosphoSitePlus	CCLE	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P15336	ATF2	P28482	MAPK1	T69	R74K	74	Missense	distal	5	no	13.621	13.486	EPSD	CCLE	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P15336	ATF2	P28482	MAPK1	T71	R74K	74	Missense	distal	3	no	13.125	13.077	PhosphoSitePlus	CCLE	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P15336	ATF2	P28482	MAPK1	S314	A319D	319	Missense	distal	5	no	8.196	8.381	EPSD	CCLE	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P15336	ATF2	P28482	MAPK1	S314	S307L	307	Missense	distal	-7	no	8.196	8.188	EPSD	CCLE	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P15336	ATF2	P28482	MAPK1	T320	A319D	319	Missense	proximal	-1	no	8.431	8.413	EPSD	CCLE	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P15336	ATF2	P28482	MAPK1	T325	A330G	330	Missense	distal	5	no	13.109	13.249	EPSD	CCLE	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P15336	ATF2	P28482	MAPK1	T325	A319D	319	Missense	distal	-6	no	13.109	13.171	EPSD	CCLE	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P15336	ATF2	P28482	MAPK1	S328	A330G	330	Missense	proximal	2	no	17.310	17.458	EPSD	CCLE	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P15336	ATF2	P28482	MAPK1	T333	A330G	330	Missense	distal	-3	no	14.496	14.675	EPSD	CCLE	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P23443	RPS6KB1	P28482	MAPK1	S447	G454V	454	Missense	distal	7	no	18.223	18.437	PhosphoSitePlus;EPSD	CCLE	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P23443	RPS6KB1	P28482	MAPK1	S452	G454V	454	Missense	proximal	2	no	13.550	13.478	EPSD	CCLE	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q92934	BAD	P28482	MAPK1	S25	S32L	32	Missense	distal	7	no	16.358	16.646	EPSD	CCLE	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q92934	BAD	P28482	MAPK1	S75	H73Q	73	Missense	proximal	-2	no	9.338	9.099	PhosphoSitePlus	CCLE	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q92934	BAD	P28482	MAPK1	S75	R70W	70	Missense	distal	-5	no	9.338	9.614	PhosphoSitePlus	CCLE	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q9GZM8	NDEL1	P28482	MAPK1	S198	C203G	203	Missense	distal	5	no	15.698	16.079	EPSD	CCLE	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q9GZM8	NDEL1	P28482	MAPK1	S231	P230L	230	Missense	proximal	-1	no	17.036	16.976	EPSD	CCLE	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q9H8Y8	GORASP2	P28482	MAPK1	T415	K420N	420	Missense	distal	5	no	13.623	13.654	EPSD	CCLE	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q9H8Y8	GORASP2	P28482	MAPK1	T418	K420N	420	Missense	proximal	2	no	8.875	8.867	EPSD	CCLE	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q9H8Y8	GORASP2	P28482	MAPK1	T433	V435L	435	Missense	proximal	2	no	15.171	15.077	EPSD	CCLE	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q9H8Y8	GORASP2	P28482	MAPK1	T433	K438R	438	Missense	distal	5	no	15.171	15.306	EPSD	CCLE	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q9H8Y8	GORASP2	P28482	MAPK1	S436	V435L	435	Missense	proximal	-1	no	10.147	10.113	EPSD	CCLE	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q9H8Y8	GORASP2	P28482	MAPK1	S436	K438R	438	Missense	proximal	2	no	10.147	10.328	EPSD	CCLE	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q9H8Y8	GORASP2	P28482	MAPK1	S436	S441C	441	Missense	distal	5	no	10.147	9.747	EPSD	CCLE	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q9H8Y8	GORASP2	P28482	MAPK1	S441	V435L	435	Missense	distal	-6	no	11.560	11.554	EPSD	CCLE	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q9H8Y8	GORASP2	P28482	MAPK1	S441	K438R	438	Missense	distal	-3	no	11.560	11.798	EPSD	CCLE	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q9H8Y8	GORASP2	P28482	MAPK1	S441	S441C	441	Missense	central	0	yes	11.560	0.000	EPSD	CCLE	8.102	Loss
CMGC_MAPK_ERK1_MAPK1_ST	P19793	RXRA	P28482	MAPK1	S21	R25Q	25	Missense	distal	4	no	16.365	16.290	EPSD	CCLE	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P19793	RXRA	P28482	MAPK1	S49	S52I	52	Missense	distal	3	no	14.718	14.776	EPSD	CCLE	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P19793	RXRA	P28482	MAPK1	T82	M77I	77	Missense	distal	-5	no	16.735	16.791	EPSD	CCLE	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P19793	RXRA	P28482	MAPK1	S225	N227S	227	Missense	proximal	2	no	8.135	8.184	EPSD	CCLE	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q9NVD7	PARVA	P28482	MAPK1	T16	S22Y	22	Missense	distal	6	no	16.129	15.510	EPSD	CCLE	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q9NVD7	PARVA	P28482	MAPK1	S19	S22Y	22	Missense	distal	3	no	19.939	19.998	EPSD	CCLE	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q9NVD7	PARVA	P28482	MAPK1	S22	S22Y	22	Missense	central	0	yes	9.420	0.000	EPSD	CCLE	8.102	Loss
CMGC_MAPK_ERK1_MAPK1_ST	Q9NVD7	PARVA	P28482	MAPK1	S28	S22Y	22	Missense	distal	-6	no	8.562	8.448	EPSD	CCLE	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	O43623	SNAI2	P28482	MAPK1	S87	D93G	93	Missense	distal	6	no	18.083	18.051	PhosphoSitePlus;EPSD	CCLE	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	O43623	SNAI2	P28482	MAPK1	S170	L171P	171	Missense	proximal	1	no	6.067	14.877	EPSD	CCLE	8.102	Gain
CMGC_MAPK_ERK1_MAPK1_ST	O43623	SNAI2	P28482	MAPK1	T234	R229W	229	Missense	distal	-5	no	8.283	8.559	EPSD	CCLE	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q8WX93	PALLD	P28482	MAPK1	S115	R120M	120	Missense	distal	5	no	14.813	14.577	EPSD	CCLE	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q8WX93	PALLD	P28482	MAPK1	S125	R120M	120	Missense	distal	-5	no	12.744	12.849	EPSD	CCLE	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q8WX93	PALLD	P28482	MAPK1	S192	E196Q	196	Missense	distal	4	no	10.428	10.357	EPSD	CCLE	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q8WX93	PALLD	P28482	MAPK1	S199	E196Q	196	Missense	distal	-3	no	12.436	12.319	EPSD	CCLE	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q8WX93	PALLD	P28482	MAPK1	S222	E229D	229	Missense	distal	7	no	14.479	14.534	EPSD	CCLE	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q8WX93	PALLD	P28482	MAPK1	S236	E229D	229	Missense	distal	-7	no	14.164	14.156	EPSD	CCLE	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q15797	SMAD1	P28482	MAPK1	S206	P207S	207	Missense	proximal	1	no	16.952	7.557	EPSD;PhosphoSitePlus	CCLE	8.102	Loss
CMGC_MAPK_ERK1_MAPK1_ST	Q15797	SMAD1	P28482	MAPK1	S214	P207S	207	Missense	distal	-7	no	16.360	16.356	EPSD;PhosphoSitePlus	CCLE	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q15797	SMAD1	P28482	MAPK1	S214	S214I	214	Missense	central	0	yes	16.360	0.000	EPSD;PhosphoSitePlus	CCLE	8.102	Loss
CMGC_MAPK_ERK1_MAPK1_ST	Q15797	SMAD1	P28482	MAPK1	S456	P460S	460	Missense	distal	4	no	12.915	12.905	EPSD	CCLE	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q15797	SMAD1	P28482	MAPK1	S462	P460S	460	Missense	proximal	-2	no	9.883	7.049	EPSD	CCLE	8.102	Loss
CMGC_MAPK_ERK1_MAPK1_ST	Q15797	SMAD1	P28482	MAPK1	S463	P460S	460	Missense	distal	-3	no	9.283	9.107	EPSD	CCLE	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q13127	REST	P28482	MAPK1	S782	E780D	780	Missense	proximal	-2	no	14.177	13.255	EPSD	CCLE	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P50616	TOB1	P28482	MAPK1	S205	V201F	201	Missense	distal	-4	no	14.727	14.736	EPSD	CCLE	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P49815	TSC2	P28482	MAPK1	S540	R537P	537	Missense	distal	-3	no	13.757	13.777	EPSD	CCLE	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P49815	TSC2	P28482	MAPK1	S540	S538F	538	Missense	proximal	-2	no	13.757	13.951	EPSD	CCLE	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P49815	TSC2	P28482	MAPK1	S664	S660N	660	Missense	distal	-4	no	17.995	18.036	PhosphoSitePlus	CCLE	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P49815	TSC2	P28482	MAPK1	S1002	L995I	995	Missense	distal	-7	no	8.547	8.527	EPSD	CCLE	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P49815	TSC2	P28482	MAPK1	S1002	N1006S	1006	Missense	distal	4	no	8.547	8.584	EPSD	CCLE	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P49815	TSC2	P28482	MAPK1	S1274	S1281P	1281	Missense	distal	7	no	9.069	9.058	EPSD	CCLE	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P49815	TSC2	P28482	MAPK1	S1411	A1416V	1416	Missense	distal	5	no	15.321	15.338	EPSD	CCLE	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P49815	TSC2	P28482	MAPK1	S1452	P1458T	1458	Missense	distal	6	no	18.155	17.945	EPSD	CCLE	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P10415	BCL2	P28482	MAPK1	S70	Q73H	73	Missense	distal	3	no	14.461	14.482	EPSD	CCLE	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P10415	BCL2	P28482	MAPK1	T74	Q73H	73	Missense	proximal	-1	no	15.881	15.880	PhosphoSitePlus;EPSD	CCLE	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P10415	BCL2	P28482	MAPK1	S87	V92L	92	Missense	distal	5	no	14.286	14.197	EPSD;PhosphoSitePlus	CCLE	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P10415	BCL2	P28482	MAPK1	S87	P88R	88	Missense	proximal	1	no	14.286	4.631	EPSD;PhosphoSitePlus	CCLE	8.102	Loss
CMGC_MAPK_ERK1_MAPK1_ST	P10415	BCL2	P28482	MAPK1	S87	A82T	82	Missense	distal	-5	no	14.286	14.264	EPSD;PhosphoSitePlus	CCLE	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q9NQ66	PLCB1	P28482	MAPK1	S501	P502I	502	Missense	proximal	1	no	17.571	7.753	EPSD	CCLE	8.102	Loss
CMGC_MAPK_ERK1_MAPK1_ST	Q15554	TERF2	P28482	MAPK1	T169	L168P	168	Missense	proximal	-1	no	11.467	11.526	EPSD	CCLE	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P17655	CAPN2	P28482	MAPK1	S50	T44A	44	Missense	distal	-6	no	8.446	8.457	PhosphoSitePlus	CCLE	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P17655	CAPN2	P28482	MAPK1	S67	R71W	71	Missense	distal	4	no	8.354	8.070	EPSD	CCLE	8.102	Loss
CMGC_MAPK_ERK1_MAPK1_ST	P17655	CAPN2	P28482	MAPK1	S277	E270Q	270	Missense	distal	-7	no	8.508	8.506	EPSD	CCLE	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P17655	CAPN2	P28482	MAPK1	T464	R461L	461	Missense	distal	-3	no	8.285	7.921	EPSD	CCLE	8.102	Loss
CMGC_MAPK_ERK1_MAPK1_ST	P30041	PRDX6	P28482	MAPK1	T177	A176V	176	Missense	proximal	-1	no	13.903	13.914	PhosphoSitePlus	CCLE	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	O75030	MITF	P28482	MAPK1	T23	K22Q	22	Missense	proximal	-1	no	10.611	10.557	EPSD	CCLE	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	O75030	MITF	P28482	MAPK1	T23	K22E	22	Missense	proximal	-1	no	10.611	10.583	EPSD	CCLE	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	O75030	MITF	P28482	MAPK1	S175	G174R	174	Missense	proximal	-1	no	8.206	8.241	EPSD	CCLE	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	O75030	MITF	P28482	MAPK1	S180	G174R	174	Missense	distal	-6	no	17.567	17.618	EPSD	CCLE	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	O75030	MITF	P28482	MAPK1	S491	S491F	491	Missense	central	0	yes	13.748	0.000	EPSD	CCLE	8.102	Loss
CMGC_MAPK_ERK1_MAPK1_ST	O75030	MITF	P28482	MAPK1	S511	S512N	512	Missense	proximal	1	no	9.061	-1.267	EPSD	CCLE	8.102	Loss
CMGC_MAPK_ERK1_MAPK1_ST	O75030	MITF	P28482	MAPK1	S515	S512N	512	Missense	distal	-3	no	8.809	8.824	EPSD	CCLE	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P03372	ESR1	P28482	MAPK1	S104	F97S	97	Missense	distal	-7	no	13.696	13.716	EPSD;PhosphoSitePlus	CCLE	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P03372	ESR1	P28482	MAPK1	S294	M297I	297	Missense	distal	3	no	14.197	14.240	EPSD	CCLE	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P09874	PARP1	P28482	MAPK1	T327	R330Q	330	Missense	distal	3	no	9.732	9.754	EPSD	CCLE	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P09874	PARP1	P28482	MAPK1	T335	R340G	340	Missense	distal	5	no	14.092	14.041	EPSD	CCLE	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P09874	PARP1	P28482	MAPK1	T335	R330Q	330	Missense	distal	-5	no	14.092	14.169	EPSD	CCLE	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P09874	PARP1	P28482	MAPK1	T361	A367D	367	Missense	distal	6	no	8.042	8.293	EPSD	CCLE	8.102	Gain
CMGC_MAPK_ERK1_MAPK1_ST	P09874	PARP1	P28482	MAPK1	T368	A367D	367	Missense	proximal	-1	no	13.208	13.189	EPSD	CCLE	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P09874	PARP1	P28482	MAPK1	S372	A367D	367	Missense	distal	-5	no	8.983	8.928	PhosphoSitePlus;EPSD	CCLE	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P09874	PARP1	P28482	MAPK1	T373	A367D	367	Missense	distal	-6	no	10.488	10.551	EPSD;PhosphoSitePlus	CCLE	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q07889	SOS1	P28482	MAPK1	S1161	P1155L	1155	Missense	distal	-6	no	9.015	8.923	EPSD	CCLE	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q13614	MTMR2	P28482	MAPK1	S58	P59H	59	Missense	proximal	1	no	13.641	5.818	PhosphoSitePlus	CCLE	8.102	Loss
CMGC_MAPK_ERK1_MAPK1_ST	Q13614	MTMR2	P28482	MAPK1	S558	Y565F	565	Missense	distal	7	no	8.303	8.133	EPSD	CCLE	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q13322	GRB10	P28482	MAPK1	T155	L159F	159	Missense	distal	4	no	12.625	12.557	EPSD	CCLE	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q13322	GRB10	P28482	MAPK1	S158	L159F	159	Missense	proximal	1	no	6.588	8.828	EPSD	CCLE	8.102	Gain
CMGC_MAPK_ERK1_MAPK1_ST	P84022	SMAD3	P28482	MAPK1	T179	P177A	177	Missense	proximal	-2	no	14.377	11.231	EPSD;PhosphoSitePlus	CCLE	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P84022	SMAD3	P28482	MAPK1	T179	P180L	180	Missense	proximal	1	no	14.377	5.568	EPSD;PhosphoSitePlus	CCLE	8.102	Loss
CMGC_MAPK_ERK1_MAPK1_ST	Q9NZ72	STMN3	P28482	MAPK1	S60	E67Q	67	Missense	distal	7	no	14.667	14.845	EPSD	CCLE	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q9NZ72	STMN3	P28482	MAPK1	S65	E67Q	67	Missense	proximal	2	no	14.438	14.328	EPSD	CCLE	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q9NZ72	STMN3	P28482	MAPK1	S68	E67Q	67	Missense	proximal	-1	no	16.119	16.092	PhosphoSitePlus	CCLE	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q9NZ72	STMN3	P28482	MAPK1	S73	E67Q	67	Missense	distal	-6	no	15.549	15.523	EPSD	CCLE	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q96I25	RBM17	P28482	MAPK1	S48	R44W	44	Missense	distal	-4	no	8.317	7.375	EPSD	CCLE	8.102	Loss
CMGC_MAPK_ERK1_MAPK1_ST	P12980	LYL1	P28482	MAPK1	S36	A35V	35	Missense	proximal	-1	no	17.074	17.085	PhosphoSitePlus	CCLE	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P12980	LYL1	P28482	MAPK1	S260	P257S	257	Missense	distal	-3	no	16.315	16.138	EPSD	CCLE	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P08047	SP1	P28482	MAPK1	T278	V284G	284	Missense	distal	6	no	12.616	12.753	EPSD	CCLE	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P55211	CASP9	P28482	MAPK1	S87	M84T	84	Missense	distal	-3	no	9.260	9.488	EPSD	CCLE	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P55211	CASP9	P28482	MAPK1	T125	R122K	122	Missense	distal	-3	no	15.221	14.983	PhosphoSitePlus	CCLE	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q9Y6W5	WASF2	P28482	MAPK1	S296	P302A	302	Missense	distal	6	no	16.752	16.455	EPSD;PhosphoSitePlus	CCLE	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q9Y6W5	WASF2	P28482	MAPK1	S308	P302A	302	Missense	distal	-6	no	16.283	16.244	PhosphoSitePlus;EPSD	CCLE	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q9Y6W5	WASF2	P28482	MAPK1	S474	R475H	475	Missense	proximal	1	no	7.167	8.998	EPSD	CCLE	8.102	Gain
CMGC_MAPK_ERK1_MAPK1_ST	O94953	KDM4B	P28482	MAPK1	S352	T345M	345	Missense	distal	-7	no	15.356	15.352	PhosphoSitePlus;EPSD	CCLE	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	O94953	KDM4B	P28482	MAPK1	T1065	R1062L	1062	Missense	distal	-3	no	14.614	14.250	EPSD;PhosphoSitePlus	CCLE	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q15788	NCOA1	P28482	MAPK1	S97	Q95K	95	Missense	proximal	-2	no	7.746	8.320	EPSD	CCLE	8.102	Gain
CMGC_MAPK_ERK1_MAPK1_ST	Q15788	NCOA1	P28482	MAPK1	S372	H368D	368	Missense	distal	-4	no	15.125	15.352	EPSD	CCLE	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q15788	NCOA1	P28482	MAPK1	S372	T377N	377	Missense	distal	5	no	15.125	15.126	EPSD	CCLE	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q15788	NCOA1	P28482	MAPK1	S372	T377S	377	Missense	distal	5	no	15.125	15.198	EPSD	CCLE	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q15788	NCOA1	P28482	MAPK1	S488	Q492L	492	Missense	distal	4	no	14.072	14.060	EPSD	CCLE	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q15788	NCOA1	P28482	MAPK1	S558	S555C	555	Missense	distal	-3	no	13.320	12.793	EPSD	CCLE	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q15788	NCOA1	P28482	MAPK1	T763	E757A	757	Missense	distal	-6	no	14.630	14.580	EPSD	CCLE	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P15923	TCF3	P28482	MAPK1	S245	P238T	238	Missense	distal	-7	no	13.753	13.736	EPSD	CCLE	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P15923	TCF3	P28482	MAPK1	T308	V304I	304	Missense	distal	-4	no	13.017	12.700	EPSD	CCLE	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P15923	TCF3	P28482	MAPK1	S341	S345L	345	Missense	distal	4	no	15.206	15.097	EPSD	CCLE	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P15923	TCF3	P28482	MAPK1	S352	S345L	345	Missense	distal	-7	no	12.993	12.985	PhosphoSitePlus;EPSD	CCLE	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P15923	TCF3	P28482	MAPK1	S379	A377V	377	Missense	proximal	-2	no	13.460	14.735	EPSD	CCLE	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P15923	TCF3	P28482	MAPK1	S379	A374D	374	Missense	distal	-5	no	13.460	13.406	EPSD	CCLE	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q96RK0	CIC	P28482	MAPK1	S12	H5Y	5	Missense	distal	-7	no	8.480	8.461	EPSD	CCLE	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q96RK0	CIC	P28482	MAPK1	S105	P103S	103	Missense	proximal	-2	no	16.034	13.200	EPSD	CCLE	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q96RK0	CIC	P28482	MAPK1	S285	T284A	284	Missense	proximal	-1	no	8.461	8.466	EPSD	CCLE	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q96RK0	CIC	P28482	MAPK1	S349	P352L	352	Missense	distal	3	no	8.071	8.160	EPSD	CCLE	8.102	Gain
CMGC_MAPK_ERK1_MAPK1_ST	Q96RK0	CIC	P28482	MAPK1	S349	P352R	352	Missense	distal	3	no	8.071	8.116	EPSD	CCLE	8.102	Gain
CMGC_MAPK_ERK1_MAPK1_ST	Q96RK0	CIC	P28482	MAPK1	S700	S694C	694	Missense	distal	-6	no	12.565	12.424	EPSD	CCLE	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q96RK0	CIC	P28482	MAPK1	S894	P887T	887	Missense	distal	-7	no	8.842	8.825	EPSD	CCLE	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q96RK0	CIC	P28482	MAPK1	S894	P897T	897	Missense	distal	3	no	8.842	8.904	EPSD	CCLE	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q96RK0	CIC	P28482	MAPK1	S904	P897T	897	Missense	distal	-7	no	15.460	15.443	EPSD	CCLE	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q96RK0	CIC	P28482	MAPK1	S1429	G1434S	1434	Missense	distal	5	no	10.046	10.066	EPSD	CCLE	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q96RK0	CIC	P28482	MAPK1	S1595	P1596R	1596	Missense	proximal	1	no	16.271	6.617	EPSD	CCLE	8.102	Loss
CMGC_MAPK_ERK1_MAPK1_ST	P14598	NCF1	P28482	MAPK1	S348	R354L	354	Missense	distal	6	no	17.083	16.784	EPSD	CCLE	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q92793	CREBBP	P28482	MAPK1	T974	P975L	975	Missense	proximal	1	no	13.267	4.457	EPSD	CCLE	8.102	Loss
CMGC_MAPK_ERK1_MAPK1_ST	Q92793	CREBBP	P28482	MAPK1	S1763	Q1760E	1760	Missense	distal	-3	no	15.448	15.565	EPSD	CCLE	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q92793	CREBBP	P28482	MAPK1	S1912	S1917A	1917	Missense	distal	5	no	12.962	12.803	EPSD	CCLE	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P32121	ARRB2	P28482	MAPK1	S360	A362T	362	Missense	proximal	2	no	11.077	11.156	EPSD	CCLE	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q96RS0	TGS1	P28482	MAPK1	T839	N832D	832	Missense	distal	-7	no	9.578	9.577	EPSD	CCLE	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q01196	RUNX1	P28482	MAPK1	S67	N69K	69	Missense	proximal	2	no	13.305	13.314	EPSD	CCLE	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q01196	RUNX1	P28482	MAPK1	S249	T243A	243	Missense	distal	-6	no	12.250	12.261	EPSD	CCLE	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q01196	RUNX1	P28482	MAPK1	S276	G282D	282	Missense	distal	6	no	17.372	17.404	PhosphoSitePlus;EPSD	CCLE	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q01196	RUNX1	P28482	MAPK1	T334	M341V	341	Missense	distal	7	no	8.231	8.154	EPSD	CCLE	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q01860	POU5F1	P28482	MAPK1	T118	P119S	119	Missense	proximal	1	no	14.457	5.062	PhosphoSitePlus;EPSD	CCLE	8.102	Loss
CMGC_MAPK_ERK1_MAPK1_ST	P49795	RGS19	P28482	MAPK1	T28	P34H	34	Missense	distal	6	no	8.654	8.348	EPSD	CCLE	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P49795	RGS19	P28482	MAPK1	S30	P34H	34	Missense	distal	4	no	15.979	15.804	EPSD	CCLE	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P49795	RGS19	P28482	MAPK1	S151	P152T	152	Missense	proximal	1	no	15.124	6.625	PhosphoSitePlus	CCLE	8.102	Loss
CMGC_MAPK_ERK1_MAPK1_ST	P49795	RGS19	P28482	MAPK1	S151	D145E	145	Missense	distal	-6	no	15.124	15.111	PhosphoSitePlus	CCLE	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q8NHW3	MAFA	P28482	MAPK1	S49	P54S	54	Missense	distal	5	no	9.940	9.958	EPSD	CCLE	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q8NHW3	MAFA	P28482	MAPK1	T53	P54S	54	Missense	proximal	1	no	12.466	3.071	EPSD	CCLE	8.102	Loss
CMGC_MAPK_ERK1_MAPK1_ST	Q8NHW3	MAFA	P28482	MAPK1	T57	P54S	54	Missense	distal	-3	no	14.890	14.714	EPSD	CCLE	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q8NHW3	MAFA	P28482	MAPK1	S65	P66S	66	Missense	proximal	1	no	14.158	4.763	EPSD;PhosphoSitePlus	CCLE	8.102	Loss
CMGC_MAPK_ERK1_MAPK1_ST	Q9BUB5	MKNK1	P28482	MAPK1	S437	R443L	443	Missense	distal	6	no	14.974	14.675	EPSD	CCLE	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q13625	TP53BP2	P28482	MAPK1	S432	S432C	432	Missense	central	0	yes	9.436	0.000	EPSD	CCLE	8.102	Loss
CMGC_MAPK_ERK1_MAPK1_ST	Q13625	TP53BP2	P28482	MAPK1	S783	P790S	790	Missense	distal	7	no	13.542	13.553	EPSD	CCLE	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q13625	TP53BP2	P28482	MAPK1	S827	S827N	827	Missense	central	0	yes	12.330	0.000	PhosphoSitePlus	CCLE	8.102	Loss
CMGC_MAPK_ERK1_MAPK1_ST	P49137	MAPKAPK2	P28482	MAPK1	T25	P19L	19	Missense	distal	-6	no	18.005	17.913	EPSD;PhosphoSitePlus	CCLE	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P49137	MAPKAPK2	P28482	MAPK1	T25	P24R	24	Missense	proximal	-1	no	18.005	17.985	EPSD;PhosphoSitePlus	CCLE	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P23396	RPS3	P28482	MAPK1	T220	K227R	227	Missense	distal	7	no	8.078	8.133	EPSD	CCLE	8.102	Gain
CMGC_MAPK_ERK1_MAPK1_ST	P23396	RPS3	P28482	MAPK1	T221	K227R	227	Missense	distal	6	no	16.982	16.818	EPSD	CCLE	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P23396	RPS3	P28482	MAPK1	S224	K227R	227	Missense	distal	3	no	9.076	9.124	EPSD	CCLE	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P17861	XBP1	P28482	MAPK1	T14	P15S	15	Missense	proximal	1	no	15.259	5.864	EPSD	CCLE	8.102	Loss
CMGC_MAPK_ERK1_MAPK1_ST	P17861	XBP1	P28482	MAPK1	S255	R251P	251	Missense	distal	-4	no	9.637	9.726	EPSD	CCLE	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q8IZP0	ABI1	P28482	MAPK1	S22	A18T	18	Missense	distal	-4	no	9.403	9.383	EPSD	CCLE	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q8IZP0	ABI1	P28482	MAPK1	S410	P416L	416	Missense	distal	6	no	14.946	14.540	PhosphoSitePlus;EPSD	CCLE	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P35658	NUP214	P28482	MAPK1	S483	A478V	478	Missense	distal	-5	no	8.551	8.522	EPSD	CCLE	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P35658	NUP214	P28482	MAPK1	S483	V481M	481	Missense	proximal	-2	no	8.551	6.409	EPSD	CCLE	8.102	Loss
CMGC_MAPK_ERK1_MAPK1_ST	P35658	NUP214	P28482	MAPK1	T533	A535V	535	Missense	proximal	2	no	13.509	13.585	EPSD	CCLE	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P35658	NUP214	P28482	MAPK1	S537	A535V	535	Missense	proximal	-2	no	13.011	14.285	EPSD	CCLE	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P35658	NUP214	P28482	MAPK1	S666	A673T	673	Missense	distal	7	no	15.014	14.985	EPSD	CCLE	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P35658	NUP214	P28482	MAPK1	T670	A673T	673	Missense	distal	3	no	13.828	13.811	EPSD	CCLE	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P35658	NUP214	P28482	MAPK1	S678	A673T	673	Missense	distal	-5	no	16.723	16.701	EPSD	CCLE	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P35658	NUP214	P28482	MAPK1	T1156	A1159T	1159	Missense	distal	3	no	12.647	12.631	EPSD	CCLE	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P35658	NUP214	P28482	MAPK1	T1178	Q1183H	1183	Missense	distal	5	no	9.949	9.943	EPSD	CCLE	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P35658	NUP214	P28482	MAPK1	S1272	P1269L	1269	Missense	distal	-3	no	13.561	13.177	EPSD	CCLE	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P35658	NUP214	P28482	MAPK1	S1978	G1971D	1971	Missense	distal	-7	no	13.644	13.659	EPSD	CCLE	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q15672	TWIST1	P28482	MAPK1	S8	S6C	6	Missense	proximal	-2	no	13.320	12.388	EPSD	CCLE	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q15672	TWIST1	P28482	MAPK1	S8	D4E	4	Missense	distal	-4	no	13.320	13.306	EPSD	CCLE	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q15672	TWIST1	P28482	MAPK1	S11	S6C	6	Missense	distal	-5	no	16.599	16.802	EPSD	CCLE	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q15672	TWIST1	P28482	MAPK1	S11	D4E	4	Missense	distal	-7	no	16.599	16.607	EPSD	CCLE	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q15796	SMAD2	P28482	MAPK1	T172	L179S	179	Missense	distal	7	no	12.938	12.649	EPSD	CCLE	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q15796	SMAD2	P28482	MAPK1	S250	L254F	254	Missense	distal	4	no	16.438	16.370	EPSD;PhosphoSitePlus	CCLE	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q15796	SMAD2	P28482	MAPK1	T253	L254F	254	Missense	proximal	1	no	7.461	9.701	EPSD	CCLE	8.102	Gain
CMGC_MAPK_ERK1_MAPK1_ST	Q15796	SMAD2	P28482	MAPK1	S255	L254F	254	Missense	proximal	-1	no	16.866	16.836	PhosphoSitePlus;EPSD	CCLE	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P01100	FOS	P28482	MAPK1	S277	S278Y	278	Missense	proximal	1	no	6.884	9.270	EPSD	CCLE	8.102	Gain
CMGC_MAPK_ERK1_MAPK1_ST	Q14674	ESPL1	P28482	MAPK1	S330	P329T	329	Missense	proximal	-1	no	13.223	13.181	EPSD	CCLE	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q14674	ESPL1	P28482	MAPK1	S1126	K1130E	1130	Missense	distal	4	no	14.009	13.994	PhosphoSitePlus	CCLE	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q14674	ESPL1	P28482	MAPK1	T1210	P1216Q	1216	Missense	distal	6	no	14.034	13.747	EPSD	CCLE	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q14674	ESPL1	P28482	MAPK1	S1501	L1505P	1505	Missense	distal	4	no	8.514	8.634	EPSD	CCLE	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P19878	NCF2	P28482	MAPK1	S332	K338T	338	Missense	distal	6	no	14.060	13.793	EPSD	CCLE	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P28562	DUSP1	P28482	MAPK1	S359	S364Y	364	Missense	distal	5	no	16.428	16.139	EPSD	CCLE	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P28562	DUSP1	P28482	MAPK1	S364	S364Y	364	Missense	central	0	yes	16.160	0.000	EPSD	CCLE	8.102	Loss
CMGC_MAPK_ERK1_MAPK1_ST	Q15648	MED1	P28482	MAPK1	S1453	T1457P	1457	Missense	distal	4	no	14.493	14.616	EPSD	CCLE	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q15648	MED1	P28482	MAPK1	T1457	T1457P	1457	Missense	central	0	yes	14.347	0.000	PhosphoSitePlus;EPSD	CCLE	8.102	Loss
CMGC_MAPK_ERK1_MAPK1_ST	P19525	EIF2AK2	P28482	MAPK1	S456	S462L	462	Missense	distal	6	no	14.472	14.065	EPSD	CCLE	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q92974	ARHGEF2	P28482	MAPK1	S163	R168H	168	Missense	distal	5	no	15.493	15.316	EPSD	CCLE	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q92974	ARHGEF2	P28482	MAPK1	T455	A453T	453	Missense	proximal	-2	no	11.810	12.257	EPSD	CCLE	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q92974	ARHGEF2	P28482	MAPK1	S645	L646P	646	Missense	proximal	1	no	4.247	13.057	EPSD	CCLE	8.102	Gain
CMGC_MAPK_ERK1_MAPK1_ST	Q92974	ARHGEF2	P28482	MAPK1	S648	L646P	646	Missense	proximal	-2	no	16.786	18.703	EPSD	CCLE	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q92974	ARHGEF2	P28482	MAPK1	S648	R642S	642	Missense	distal	-6	no	16.786	16.752	EPSD	CCLE	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q92974	ARHGEF2	P28482	MAPK1	S696	G692S	692	Missense	distal	-4	no	15.514	15.780	EPSD	CCLE	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q92974	ARHGEF2	P28482	MAPK1	S932	G931E	931	Missense	proximal	-1	no	13.424	13.463	EPSD	CCLE	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	O94811	TPPP	P28482	MAPK1	T14	P15L	15	Missense	proximal	1	no	15.180	6.370	EPSD	CCLE	8.102	Loss
CMGC_MAPK_ERK1_MAPK1_ST	O94811	TPPP	P28482	MAPK1	S18	P15L	15	Missense	distal	-3	no	19.644	19.261	EPSD;PhosphoSitePlus	CCLE	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	O75582	RPS6KA5	P28482	MAPK1	S15	D17G	17	Missense	proximal	2	no	8.098	8.132	EPSD	CCLE	8.102	Gain
CMGC_MAPK_ERK1_MAPK1_ST	O75582	RPS6KA5	P28482	MAPK1	S15	A12V	12	Missense	distal	-3	no	8.098	8.158	EPSD	CCLE	8.102	Gain
CMGC_MAPK_ERK1_MAPK1_ST	P29590	PML	P28482	MAPK1	T592	E598K	598	Missense	distal	6	no	8.676	8.700	EPSD	CCLE	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q15700	DLG2	P28482	MAPK1	S65	S70G	70	Missense	distal	5	no	13.967	13.948	EPSD	CCLE	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q15700	DLG2	P28482	MAPK1	S328	M334K	334	Missense	distal	6	no	13.340	13.830	EPSD	CCLE	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q15700	DLG2	P28482	MAPK1	S360	Y364F	364	Missense	distal	4	no	16.803	16.820	EPSD	CCLE	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q15700	DLG2	P28482	MAPK1	S365	E368D	368	Missense	distal	3	no	14.400	14.496	EPSD	CCLE	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q15700	DLG2	P28482	MAPK1	S365	Y364F	364	Missense	proximal	-1	no	14.400	14.386	EPSD	CCLE	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q15700	DLG2	P28482	MAPK1	S635	R632S	632	Missense	distal	-3	no	8.685	8.528	EPSD	CCLE	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q9NRA0	SPHK2	P28482	MAPK1	S473	S477F	477	Missense	distal	4	no	14.889	14.712	EPSD	CCLE	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q9NRA0	SPHK2	P28482	MAPK1	S477	S477F	477	Missense	central	0	yes	16.777	0.000	EPSD	CCLE	8.102	Loss
CMGC_MAPK_ERK1_MAPK1_ST	Q9NRA0	SPHK2	P28482	MAPK1	S484	S477F	477	Missense	distal	-7	no	15.493	15.473	EPSD	CCLE	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P35236	PTPN7	P28482	MAPK1	T66	E69K	69	Missense	distal	3	no	14.843	14.850	PhosphoSitePlus;EPSD	CCLE	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P35236	PTPN7	P28482	MAPK1	S93	E99K	99	Missense	distal	6	no	17.799	17.822	EPSD;PhosphoSitePlus	CCLE	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P35236	PTPN7	P28482	MAPK1	S134	S134R	134	Missense	central	0	yes	8.273	0.000	EPSD	CCLE	8.102	Loss
CMGC_MAPK_ERK1_MAPK1_ST	P05412	JUN	P28482	MAPK1	S21	P20Q	20	Missense	proximal	-1	no	8.115	8.074	EPSD	CCLE	8.102	Loss
CMGC_MAPK_ERK1_MAPK1_ST	P32004	L1CAM	P28482	MAPK1	S1248	N1251T	1251	Missense	distal	3	no	15.506	15.577	PhosphoSitePlus;EPSD	CCLE	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q16665	HIF1A	P28482	MAPK1	S15	K10E	10	Missense	distal	-5	no	9.164	9.186	EPSD	CCLE	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q16665	HIF1A	P28482	MAPK1	S15	I13M	13	Missense	proximal	-2	no	9.164	7.044	EPSD	CCLE	8.102	Loss
CMGC_MAPK_ERK1_MAPK1_ST	Q08499	PDE4D	P28482	MAPK1	S202	M206I	206	Missense	distal	4	no	12.862	12.884	EPSD	CCLE	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q3V6T2	CCDC88A	P28482	MAPK1	S233	P234S	234	Missense	proximal	1	no	13.645	4.250	PhosphoSitePlus;EPSD	CCLE	8.102	Loss
CMGC_MAPK_ERK1_MAPK1_ST	Q3V6T2	CCDC88A	P28482	MAPK1	S237	P234S	234	Missense	distal	-3	no	13.613	13.436	EPSD;PhosphoSitePlus	CCLE	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q3V6T2	CCDC88A	P28482	MAPK1	S1020	E1026K	1026	Missense	distal	6	no	14.011	14.035	EPSD	CCLE	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q3V6T2	CCDC88A	P28482	MAPK1	T1421	P1422R	1422	Missense	proximal	1	no	13.471	3.817	EPSD	CCLE	8.102	Loss
CMGC_MAPK_ERK1_MAPK1_ST	Q3V6T2	CCDC88A	P28482	MAPK1	T1421	S1417Y	1417	Missense	distal	-4	no	13.471	12.882	EPSD	CCLE	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q9ULV5	HSF4	P28482	MAPK1	S40	D34N	34	Missense	distal	-6	no	15.426	15.380	EPSD	CCLE	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q8N122	RPTOR	P28482	MAPK1	S8	E2Q	2	Missense	distal	-6	no	13.924	13.898	EPSD;PhosphoSitePlus	CCLE	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q8N122	RPTOR	P28482	MAPK1	S722	R727G	727	Missense	distal	5	no	8.137	8.086	EPSD	CCLE	8.102	Loss
CMGC_MAPK_ERK1_MAPK1_ST	P49407	ARRB1	P28482	MAPK1	S412	N416T	416	Missense	distal	4	no	17.031	16.956	PhosphoSitePlus	CCLE	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q53EZ4	CEP55	P28482	MAPK1	S425	A423T	423	Missense	proximal	-2	no	14.555	15.003	PhosphoSitePlus;EPSD	CCLE	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q53EZ4	CEP55	P28482	MAPK1	S428	A423T	423	Missense	distal	-5	no	16.148	16.126	EPSD;PhosphoSitePlus	CCLE	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P33076	CIITA	P28482	MAPK1	S280	R283W	283	Missense	distal	3	no	16.876	17.026	PhosphoSitePlus;EPSD	CCLE	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P33076	CIITA	P28482	MAPK1	S288	R283W	283	Missense	distal	-5	no	12.958	13.234	EPSD;PhosphoSitePlus	CCLE	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P33076	CIITA	P28482	MAPK1	S834	G831S	831	Missense	distal	-3	no	8.103	8.115	EPSD	CCLE	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P33076	CIITA	P28482	MAPK1	S834	L833P	833	Missense	proximal	-1	no	8.103	8.163	EPSD	CCLE	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P78347	GTF2I	P28482	MAPK1	S210	S207P	207	Missense	distal	-3	no	15.139	15.316	EPSD	CCLE	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P78347	GTF2I	P28482	MAPK1	T413	T413A	413	Missense	central	0	yes	10.176	0.000	EPSD	CCLE	8.102	Loss
CMGC_MAPK_ERK1_MAPK1_ST	P78347	GTF2I	P28482	MAPK1	S515	G520E	520	Missense	distal	5	no	11.388	11.363	EPSD	CCLE	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P78347	GTF2I	P28482	MAPK1	S620	G615R	615	Missense	distal	-5	no	11.425	11.405	EPSD	CCLE	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P78347	GTF2I	P28482	MAPK1	S620	S620R	620	Missense	central	0	yes	11.425	0.000	EPSD	CCLE	8.102	Loss
CMGC_MAPK_ERK1_MAPK1_ST	P78347	GTF2I	P28482	MAPK1	S651	G656E	656	Missense	distal	5	no	9.846	9.821	EPSD	CCLE	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P78347	GTF2I	P28482	MAPK1	T785	R781Q	781	Missense	distal	-4	no	10.603	10.500	EPSD	CCLE	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P78347	GTF2I	P28482	MAPK1	T785	P789L	789	Missense	distal	4	no	10.603	10.483	EPSD	CCLE	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P78347	GTF2I	P28482	MAPK1	T978	I981K	981	Missense	distal	3	no	9.351	9.221	EPSD	CCLE	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q14790	CASP8	P28482	MAPK1	S16	E12Q	12	Missense	distal	-4	no	8.781	8.618	EPSD	CCLE	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P37231	PPARG	P28482	MAPK1	S273	M280I	280	Missense	distal	7	no	11.631	11.819	EPSD	CCLE	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q9ULC4	MCTS1	P28482	MAPK1	S118	I111V	111	Missense	distal	-7	no	13.945	13.958	EPSD	CCLE	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q9ULC4	MCTS1	P28482	MAPK1	S118	G120R	120	Missense	proximal	2	no	13.945	14.040	EPSD	CCLE	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P42229	STAT5A	P28482	MAPK1	S128	E122K	122	Missense	distal	-6	no	13.396	13.370	EPSD	CCLE	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P42229	STAT5A	P28482	MAPK1	S780	D776A	776	Missense	distal	-4	no	19.102	18.823	PhosphoSitePlus	CCLE	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P42229	STAT5A	P28482	MAPK1	S780	S777P	777	Missense	distal	-3	no	19.102	19.278	PhosphoSitePlus	CCLE	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q8N9N5	BANP	P28482	MAPK1	S90	I92T	92	Missense	proximal	2	no	12.929	13.049	EPSD	CCLE	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q8N9N5	BANP	P28482	MAPK1	S100	A98S	98	Missense	proximal	-2	no	14.601	14.913	EPSD	CCLE	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q8N9N5	BANP	P28482	MAPK1	S100	T107M	107	Missense	distal	7	no	14.601	14.808	EPSD	CCLE	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q8N9N5	BANP	P28482	MAPK1	T352	T352P	352	Missense	central	0	yes	12.550	0.000	EPSD;PhosphoSitePlus	CCLE	8.102	Loss
CMGC_MAPK_ERK1_MAPK1_ST	O00429	DNM1L	P28482	MAPK1	S526	R522T	522	Missense	distal	-4	no	8.336	8.112	EPSD	CCLE	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	O00429	DNM1L	P28482	MAPK1	S548	S548P	548	Missense	central	0	yes	14.142	0.000	EPSD	CCLE	8.102	Loss
CMGC_MAPK_ERK1_MAPK1_ST	P14635	CCNB1	P28482	MAPK1	S116	K114N	114	Missense	proximal	-2	no	15.847	15.446	EPSD	CCLE	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q9H9S0	NANOG	P28482	MAPK1	S52	M58V	58	Missense	distal	6	no	10.829	11.047	PhosphoSitePlus;EPSD	CCLE	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q9H9S0	NANOG	P28482	MAPK1	S65	M58V	58	Missense	distal	-7	no	15.041	15.044	EPSD;PhosphoSitePlus	CCLE	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q9H9S0	NANOG	P28482	MAPK1	S65	P66T	66	Missense	proximal	1	no	15.041	6.542	EPSD;PhosphoSitePlus	CCLE	8.102	Loss
CMGC_MAPK_ERK1_MAPK1_ST	Q9H9S0	NANOG	P28482	MAPK1	S71	P66T	66	Missense	distal	-5	no	11.627	11.730	EPSD	CCLE	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q9H9S0	NANOG	P28482	MAPK1	S258	N257H	257	Missense	proximal	-1	no	17.279	17.230	EPSD	CCLE	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q8IW41	MAPKAPK5	P28482	MAPK1	S212	P213L	213	Missense	proximal	1	no	14.838	6.028	EPSD	CCLE	8.102	Loss
CMGC_MAPK_ERK1_MAPK1_ST	Q8IW41	MAPKAPK5	P28482	MAPK1	T214	P213L	213	Missense	proximal	-1	no	14.150	14.090	EPSD	CCLE	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q8IW41	MAPKAPK5	P28482	MAPK1	T217	P213L	213	Missense	distal	-4	no	11.667	11.362	EPSD	CCLE	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P61978	HNRNPK	P28482	MAPK1	S116	T120I	120	Missense	distal	4	no	16.136	16.082	EPSD	CCLE	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P61978	HNRNPK	P28482	MAPK1	S214	R221C	221	Missense	distal	7	no	7.588	8.243	EPSD	CCLE	8.102	Gain
CMGC_MAPK_ERK1_MAPK1_ST	P61978	HNRNPK	P28482	MAPK1	S216	R221C	221	Missense	distal	5	no	12.959	12.528	EPSD	CCLE	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P29966	MARCKS	P28482	MAPK1	S27	A25T	25	Missense	proximal	-2	no	15.041	15.489	EPSD	CCLE	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P29966	MARCKS	P28482	MAPK1	S46	A50T	50	Missense	distal	4	no	13.676	13.657	PhosphoSitePlus	CCLE	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P29966	MARCKS	P28482	MAPK1	S81	A79V	79	Missense	proximal	-2	no	13.857	15.131	EPSD	CCLE	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P29966	MARCKS	P28482	MAPK1	S81	A84S	84	Missense	distal	3	no	13.857	13.848	EPSD	CCLE	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P29966	MARCKS	P28482	MAPK1	S101	A95G	95	Missense	distal	-6	no	11.917	11.914	EPSD	CCLE	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P29966	MARCKS	P28482	MAPK1	S101	E106K	106	Missense	distal	5	no	11.917	11.858	EPSD	CCLE	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P29966	MARCKS	P28482	MAPK1	S118	E123K	123	Missense	distal	5	no	16.251	16.192	EPSD	CCLE	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P29966	MARCKS	P28482	MAPK1	S118	E123A	123	Missense	distal	5	no	16.251	16.136	EPSD	CCLE	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P29966	MARCKS	P28482	MAPK1	S118	G124R	124	Missense	distal	6	no	16.251	16.221	EPSD	CCLE	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P29966	MARCKS	P28482	MAPK1	S135	P136L	136	Missense	proximal	1	no	13.528	4.718	EPSD	CCLE	8.102	Loss
CMGC_MAPK_ERK1_MAPK1_ST	P29966	MARCKS	P28482	MAPK1	T143	P136L	136	Missense	distal	-7	no	11.782	11.770	EPSD	CCLE	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P29966	MARCKS	P28482	MAPK1	T143	S145A	145	Missense	proximal	2	no	11.782	11.680	EPSD	CCLE	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P29966	MARCKS	P28482	MAPK1	S145	S145A	145	Missense	central	0	yes	13.205	0.000	EPSD	CCLE	8.102	Loss
CMGC_MAPK_ERK1_MAPK1_ST	P29966	MARCKS	P28482	MAPK1	T150	S145A	145	Missense	distal	-5	no	12.657	12.708	EPSD	CCLE	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	O43524	FOXO3	P28482	MAPK1	S26	R27G	27	Missense	proximal	1	no	10.103	9.692	EPSD	CCLE	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	O43524	FOXO3	P28482	MAPK1	S43	Q41K	41	Missense	proximal	-2	no	12.087	12.661	EPSD	CCLE	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	O43524	FOXO3	P28482	MAPK1	S446	R444C	444	Missense	proximal	-2	no	14.355	12.407	EPSD	CCLE	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	O43524	FOXO3	P28482	MAPK1	S667	P672S	672	Missense	distal	5	no	10.107	10.125	EPSD	CCLE	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P24941	CDK2	P28482	MAPK1	T47	E51D	51	Missense	distal	4	no	10.340	10.270	EPSD	CCLE	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q05209	PTPN12	P28482	MAPK1	S323	S324P	324	Missense	proximal	1	no	3.266	12.661	EPSD	CCLE	8.102	Gain
CMGC_MAPK_ERK1_MAPK1_ST	Q05209	PTPN12	P28482	MAPK1	S588	T587P	587	Missense	proximal	-1	no	14.283	14.325	EPSD	CCLE	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q05209	PTPN12	P28482	MAPK1	T593	T587P	587	Missense	distal	-6	no	13.862	13.912	EPSD	CCLE	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q05209	PTPN12	P28482	MAPK1	T593	N599H	599	Missense	distal	6	no	13.862	13.653	EPSD	CCLE	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q05209	PTPN12	P28482	MAPK1	S596	N599H	599	Missense	distal	3	no	9.774	9.871	EPSD	CCLE	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q05209	PTPN12	P28482	MAPK1	S632	T635I	635	Missense	distal	3	no	8.058	8.124	EPSD	CCLE	8.102	Gain
CMGC_MAPK_ERK1_MAPK1_ST	Q07820	MCL1	P28482	MAPK1	T70	R74L	74	Missense	distal	4	no	13.123	13.036	EPSD	CCLE	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q07820	MCL1	P28482	MAPK1	T70	R74Q	74	Missense	distal	4	no	13.123	13.049	EPSD	CCLE	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q07820	MCL1	P28482	MAPK1	T70	S73P	73	Missense	distal	3	no	13.123	13.054	EPSD	CCLE	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q07820	MCL1	P28482	MAPK1	S73	R74L	74	Missense	proximal	1	no	8.063	8.908	EPSD	CCLE	8.102	Gain
CMGC_MAPK_ERK1_MAPK1_ST	Q07820	MCL1	P28482	MAPK1	S73	R74Q	74	Missense	proximal	1	no	8.063	9.224	EPSD	CCLE	8.102	Gain
CMGC_MAPK_ERK1_MAPK1_ST	Q07820	MCL1	P28482	MAPK1	T92	D88N	88	Missense	distal	-4	no	13.543	13.515	EPSD	CCLE	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q07820	MCL1	P28482	MAPK1	T163	T156R	156	Missense	distal	-7	no	17.184	17.196	PhosphoSitePlus	CCLE	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P68400	CSNK2A1	P28482	MAPK1	T13	T13I	13	Missense	central	0	yes	8.190	0.000	EPSD	CCLE	8.102	Loss
CMGC_MAPK_ERK1_MAPK1_ST	P68400	CSNK2A1	P28482	MAPK1	T17	T13I	13	Missense	distal	-4	no	9.899	9.542	EPSD	CCLE	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P68400	CSNK2A1	P28482	MAPK1	T344	M339I	339	Missense	distal	-5	no	15.195	15.251	EPSD	CCLE	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P68400	CSNK2A1	P28482	MAPK1	S362	G369S	369	Missense	distal	7	no	14.277	14.208	PhosphoSitePlus;EPSD	CCLE	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P68400	CSNK2A1	P28482	MAPK1	S370	P371L	371	Missense	proximal	1	no	16.132	7.322	EPSD	CCLE	8.102	Loss
CMGC_MAPK_ERK1_MAPK1_ST	P68400	CSNK2A1	P28482	MAPK1	S370	G369S	369	Missense	proximal	-1	no	16.132	16.143	EPSD	CCLE	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q08493	PDE4C	P28482	MAPK1	S114	R117C	117	Missense	distal	3	no	8.476	8.603	EPSD	CCLE	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q08493	PDE4C	P28482	MAPK1	S641	N647Y	647	Missense	distal	6	no	17.959	17.436	EPSD	CCLE	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q08493	PDE4C	P28482	MAPK1	S641	D644N	644	Missense	distal	3	no	17.959	17.863	EPSD	CCLE	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q96LC9	BMF	P28482	MAPK1	S109	R103W	103	Missense	distal	-6	no	9.393	9.172	EPSD	CCLE	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q15746	MYLK	P28482	MAPK1	S16	D20G	20	Missense	distal	4	no	8.118	8.165	EPSD	CCLE	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q15746	MYLK	P28482	MAPK1	T978	V971A	971	Missense	distal	-7	no	16.073	16.089	EPSD	CCLE	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q15746	MYLK	P28482	MAPK1	T1230	K1224M	1224	Missense	distal	-6	no	14.393	14.324	EPSD	CCLE	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	O75581	LRP6	P28482	MAPK1	S1431	L1432M	1432	Missense	proximal	1	no	8.341	2.448	EPSD	CCLE	8.102	Loss
CMGC_MAPK_ERK1_MAPK1_ST	Q02447	SP3	P28482	MAPK1	S73	E78D	78	Missense	distal	5	no	15.704	15.774	PhosphoSitePlus	CCLE	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q02447	SP3	P28482	MAPK1	S73	P74L	74	Missense	proximal	1	no	15.704	6.895	PhosphoSitePlus	CCLE	8.102	Loss
CMGC_MAPK_ERK1_MAPK1_ST	Q02447	SP3	P28482	MAPK1	S544	H537Y	537	Missense	distal	-7	no	12.285	12.266	EPSD	CCLE	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q8IX03	WWC1	P28482	MAPK1	S358	P359L	359	Missense	proximal	1	no	15.100	6.291	EPSD	CCLE	8.102	Loss
CMGC_MAPK_ERK1_MAPK1_ST	Q8IX03	WWC1	P28482	MAPK1	S876	D880H	880	Missense	distal	4	no	13.752	13.684	EPSD	CCLE	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P01106	MYC	P28482	MAPK1	T58	E54K	54	Missense	distal	-4	no	15.566	15.584	EPSD;PhosphoSitePlus	CCLE	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P01106	MYC	P28482	MAPK1	T58	P57H	57	Missense	proximal	-1	no	15.566	15.524	EPSD;PhosphoSitePlus	CCLE	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P01106	MYC	P28482	MAPK1	S62	P57H	57	Missense	distal	-5	no	14.519	14.644	PhosphoSitePlus;EPSD	CCLE	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P01106	MYC	P28482	MAPK1	S62	L69I	69	Missense	distal	7	no	14.519	14.779	PhosphoSitePlus;EPSD	CCLE	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P01106	MYC	P28482	MAPK1	S71	L69I	69	Missense	proximal	-2	no	14.405	14.428	EPSD	CCLE	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P01106	MYC	P28482	MAPK1	S71	Y74S	74	Missense	distal	3	no	14.405	14.347	EPSD	CCLE	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P01106	MYC	P28482	MAPK1	S71	T78R	78	Missense	distal	7	no	14.405	14.256	EPSD	CCLE	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P01106	MYC	P28482	MAPK1	T78	Y74S	74	Missense	distal	-4	no	15.642	16.231	EPSD	CCLE	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P01106	MYC	P28482	MAPK1	T78	T78R	78	Missense	central	0	yes	15.642	0.000	EPSD	CCLE	8.102	Loss
CMGC_MAPK_ERK1_MAPK1_ST	P01106	MYC	P28482	MAPK1	T78	L82F	82	Missense	distal	4	no	15.642	15.574	EPSD	CCLE	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P01106	MYC	P28482	MAPK1	S81	Y74S	74	Missense	distal	-7	no	8.464	8.495	EPSD	CCLE	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P01106	MYC	P28482	MAPK1	S81	T78R	78	Missense	distal	-3	no	8.464	8.653	EPSD	CCLE	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P01106	MYC	P28482	MAPK1	S81	L82F	82	Missense	proximal	1	no	8.464	10.704	EPSD	CCLE	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P01106	MYC	P28482	MAPK1	S81	N86H	86	Missense	distal	5	no	8.464	8.391	EPSD	CCLE	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P01106	MYC	P28482	MAPK1	S204	K206T	206	Missense	proximal	2	no	12.836	12.853	EPSD	CCLE	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P14784	IL2RB	P28482	MAPK1	S431	S431F	431	Missense	central	0	yes	13.075	0.000	EPSD	CCLE	8.102	Loss
CMGC_MAPK_ERK1_MAPK1_ST	P14784	IL2RB	P28482	MAPK1	S458	M455I	455	Missense	distal	-3	no	8.389	8.385	EPSD	CCLE	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P14784	IL2RB	P28482	MAPK1	T476	T476M	476	Missense	central	0	yes	15.778	0.000	PhosphoSitePlus	CCLE	8.102	Loss
CMGC_MAPK_ERK1_MAPK1_ST	P06239	LCK	P28482	MAPK1	S156	A160T	160	Missense	distal	4	no	8.235	8.216	EPSD	CCLE	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P06239	LCK	P28482	MAPK1	S162	A160T	160	Missense	proximal	-2	no	7.940	8.388	EPSD	CCLE	8.102	Gain
CMGC_MAPK_ERK1_MAPK1_ST	P42702	LIFR	P28482	MAPK1	S534	P535T	535	Missense	proximal	1	no	16.663	8.164	EPSD	CCLE	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P42702	LIFR	P28482	MAPK1	S534	T531A	531	Missense	distal	-3	no	16.663	16.505	EPSD	CCLE	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P42702	LIFR	P28482	MAPK1	T541	P535T	535	Missense	distal	-6	no	11.630	11.580	EPSD	CCLE	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P42702	LIFR	P28482	MAPK1	T904	E909K	909	Missense	distal	5	no	15.958	15.898	EPSD	CCLE	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P42702	LIFR	P28482	MAPK1	S1056	S1059N	1059	Missense	distal	3	no	10.056	9.978	EPSD	CCLE	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P42702	LIFR	P28482	MAPK1	S1059	S1059N	1059	Missense	central	0	yes	13.739	0.000	EPSD	CCLE	8.102	Loss
CMGC_MAPK_ERK1_MAPK1_ST	P42702	LIFR	P28482	MAPK1	S1062	S1059N	1059	Missense	distal	-3	no	8.299	8.314	EPSD	CCLE	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P62070	RRAS2	P28482	MAPK1	S186	P189L	189	Missense	distal	3	no	19.203	19.293	PhosphoSitePlus	CCLE	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P62070	RRAS2	P28482	MAPK1	T190	P189L	189	Missense	proximal	-1	no	8.911	8.851	EPSD	CCLE	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q00059	TFAM	P28482	MAPK1	S56	K52T	52	Missense	distal	-4	no	8.734	8.431	EPSD	CCLE	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q05682	CALD1	P28482	MAPK1	S153	R156H	156	Missense	distal	3	no	8.468	8.511	EPSD	CCLE	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q05682	CALD1	P28482	MAPK1	S724	F722L	722	Missense	proximal	-2	no	14.776	15.499	EPSD	CCLE	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q05682	CALD1	P28482	MAPK1	T730	T735I	735	Missense	distal	5	no	14.466	14.222	EPSD	CCLE	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P46527	CDKN1B	P28482	MAPK1	S10	S12I	12	Missense	proximal	2	no	14.720	14.577	PhosphoSitePlus;EPSD	CCLE	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P22736	NR4A1	P28482	MAPK1	S95	S98F	98	Missense	distal	3	no	12.717	12.779	EPSD	CCLE	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P22736	NR4A1	P28482	MAPK1	S237	H239Y	239	Missense	proximal	2	no	18.051	17.985	EPSD	CCLE	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P22736	NR4A1	P28482	MAPK1	S360	S367F	367	Missense	distal	7	no	13.556	13.903	EPSD	CCLE	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P27708	CAD	P28482	MAPK1	T166	T172A	172	Missense	distal	6	no	15.983	15.897	EPSD	CCLE	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P27708	CAD	P28482	MAPK1	T456	Y459D	459	Missense	distal	3	no	15.215	15.174	PhosphoSitePlus	CCLE	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q00613	HSF1	P28482	MAPK1	S241	P243L	243	Missense	proximal	2	no	8.721	8.573	EPSD	CCLE	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q00613	HSF1	P28482	MAPK1	S244	P243L	243	Missense	proximal	-1	no	13.950	13.890	EPSD	CCLE	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q00613	HSF1	P28482	MAPK1	S290	R287M	287	Missense	distal	-3	no	8.815	8.397	EPSD	CCLE	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q00613	HSF1	P28482	MAPK1	S292	R287M	287	Missense	distal	-5	no	14.238	14.343	EPSD	CCLE	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q00613	HSF1	P28482	MAPK1	S368	E371K	371	Missense	distal	3	no	8.326	8.333	EPSD	CCLE	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q00613	HSF1	P28482	MAPK1	S419	V424M	424	Missense	distal	5	no	14.430	14.368	EPSD	CCLE	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q9Y6K1	DNMT3A	P28482	MAPK1	S15	G10R	10	Missense	distal	-5	no	8.539	8.519	EPSD	CCLE	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q9Y6K1	DNMT3A	P28482	MAPK1	T65	P69R	69	Missense	distal	4	no	13.845	13.812	EPSD	CCLE	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q9Y6K1	DNMT3A	P28482	MAPK1	S75	P69R	69	Missense	distal	-6	no	11.951	11.959	EPSD	CCLE	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q9UBN7	HDAC6	P28482	MAPK1	T1021	I1019V	1019	Missense	proximal	-2	no	14.144	14.165	EPSD	CCLE	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P33981	TTK	P28482	MAPK1	S80	L87F	87	Missense	distal	7	no	9.018	9.077	EPSD	CCLE	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P33981	TTK	P28482	MAPK1	S214	A211T	211	Missense	distal	-3	no	8.447	8.605	EPSD	CCLE	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P33981	TTK	P28482	MAPK1	S281	K287N	287	Missense	distal	6	no	15.075	14.922	EPSD	CCLE	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q12931	TRAP1	P28482	MAPK1	S361	R368C	368	Missense	distal	7	no	7.946	8.601	EPSD	CCLE	8.102	Gain
CMGC_MAPK_ERK1_MAPK1_ST	Q12931	TRAP1	P28482	MAPK1	S568	R567K	567	Missense	proximal	-1	no	10.208	10.240	EPSD	CCLE	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P19419	ELK1	P28482	MAPK1	T336	S339L	339	Missense	distal	3	no	13.215	13.235	EPSD	CCLE	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P19419	ELK1	P28482	MAPK1	T353	P358H	358	Missense	distal	5	no	12.838	12.711	EPSD	CCLE	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P19419	ELK1	P28482	MAPK1	T363	T368P	368	Missense	distal	5	no	15.013	15.069	EPSD	CCLE	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P19419	ELK1	P28482	MAPK1	T363	P358H	358	Missense	distal	-5	no	15.013	15.138	EPSD	CCLE	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P19419	ELK1	P28482	MAPK1	T368	T368P	368	Missense	central	0	yes	15.156	0.000	EPSD	CCLE	8.102	Loss
CMGC_MAPK_ERK1_MAPK1_ST	P19419	ELK1	P28482	MAPK1	S383	A386V	386	Missense	distal	3	no	13.857	13.836	PhosphoSitePlus	CCLE	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P19419	ELK1	P28482	MAPK1	S389	A386V	386	Missense	distal	-3	no	13.963	14.023	EPSD	CCLE	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q92908	GATA6	P28482	MAPK1	S377	P373L	373	Missense	distal	-4	no	9.558	9.254	EPSD	CCLE	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q92908	GATA6	P28482	MAPK1	T515	P513H	513	Missense	proximal	-2	no	15.246	12.491	EPSD	CCLE	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q92908	GATA6	P28482	MAPK1	T515	T517I	517	Missense	proximal	2	no	15.246	15.125	EPSD	CCLE	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P04637	TP53	P28482	MAPK1	S33	E28Q	28	Missense	distal	-5	no	13.820	13.920	EPSD	CCLE	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q14686	NCOA6	P28482	MAPK1	T678	S685P	685	Missense	distal	7	no	15.371	15.361	EPSD	CCLE	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q14686	NCOA6	P28482	MAPK1	T1211	R1218I	1218	Missense	distal	7	no	15.809	16.353	EPSD	CCLE	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q14686	NCOA6	P28482	MAPK1	S1216	R1218I	1218	Missense	proximal	2	no	14.689	14.405	EPSD	CCLE	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q14686	NCOA6	P28482	MAPK1	T1224	R1218I	1218	Missense	distal	-6	no	16.939	16.803	EPSD	CCLE	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q14686	NCOA6	P28482	MAPK1	S1325	R1330C	1330	Missense	distal	5	no	14.502	14.071	EPSD	CCLE	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q14686	NCOA6	P28482	MAPK1	S1751	P1758H	1758	Missense	distal	7	no	13.564	13.798	EPSD	CCLE	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q14686	NCOA6	P28482	MAPK1	S1756	P1758H	1758	Missense	proximal	2	no	8.234	8.105	EPSD	CCLE	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q14686	NCOA6	P28482	MAPK1	S1892	T1890A	1890	Missense	proximal	-2	no	14.453	14.006	EPSD	CCLE	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P14921	ETS1	P28482	MAPK1	T38	M44T	44	Missense	distal	6	no	15.656	15.879	PhosphoSitePlus	CCLE	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P14921	ETS1	P28482	MAPK1	T38	V34A	34	Missense	distal	-4	no	15.656	15.717	PhosphoSitePlus	CCLE	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P14921	ETS1	P28482	MAPK1	S282	S285R	285	Missense	distal	3	no	8.112	8.089	EPSD	CCLE	8.102	Loss
CMGC_MAPK_ERK1_MAPK1_ST	P14921	ETS1	P28482	MAPK1	S285	S285R	285	Missense	central	0	yes	8.754	0.000	EPSD	CCLE	8.102	Loss
CMGC_MAPK_ERK1_MAPK1_ST	Q9NRF2	SH2B1	P28482	MAPK1	S25	P21L	21	Missense	distal	-4	no	13.882	13.577	EPSD	CCLE	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q9NRF2	SH2B1	P28482	MAPK1	S96	E100D	100	Missense	distal	4	no	15.960	15.890	PhosphoSitePlus	CCLE	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q9NRF2	SH2B1	P28482	MAPK1	S102	E100D	100	Missense	proximal	-2	no	13.059	12.137	EPSD	CCLE	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q9NRF2	SH2B1	P28482	MAPK1	S384	M388V	388	Missense	distal	4	no	12.580	12.668	EPSD	CCLE	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P53355	DAPK1	P28482	MAPK1	T180	K175I	175	Missense	distal	-5	no	11.610	11.816	EPSD	CCLE	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P53355	DAPK1	P28482	MAPK1	T180	V184L	184	Missense	distal	4	no	11.610	11.599	EPSD	CCLE	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P53355	DAPK1	P28482	MAPK1	S321	F322Y	322	Missense	proximal	1	no	8.189	7.750	EPSD	CCLE	8.102	Loss
CMGC_MAPK_ERK1_MAPK1_ST	P41182	BCL6	P28482	MAPK1	S3	A2T	2	Missense	proximal	-1	no	11.451	11.446	EPSD	CCLE	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P41182	BCL6	P28482	MAPK1	S250	C254S	254	Missense	distal	4	no	15.929	16.211	EPSD	CCLE	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P41182	BCL6	P28482	MAPK1	S260	C254S	254	Missense	distal	-6	no	15.090	15.230	EPSD	CCLE	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P41182	BCL6	P28482	MAPK1	S457	E463K	463	Missense	distal	6	no	13.867	13.890	EPSD	CCLE	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P41182	BCL6	P28482	MAPK1	S466	E463K	463	Missense	distal	-3	no	11.972	11.894	EPSD	CCLE	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q13164	MAPK7	P28482	MAPK1	T280	V285M	285	Missense	distal	5	no	14.924	14.862	EPSD	CCLE	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q13164	MAPK7	P28482	MAPK1	S282	V285M	285	Missense	distal	3	no	14.633	14.661	EPSD	CCLE	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q13164	MAPK7	P28482	MAPK1	T553	D554Y	554	Missense	proximal	1	no	10.272	11.959	EPSD	CCLE	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q13164	MAPK7	P28482	MAPK1	T594	P587L	587	Missense	distal	-7	no	14.134	14.122	EPSD	CCLE	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q01844	EWSR1	P28482	MAPK1	T79	T75I	75	Missense	distal	-4	no	12.809	12.452	PhosphoSitePlus	CCLE	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q9H9Z2	LIN28A	P28482	MAPK1	S200	T202A	202	Missense	proximal	2	no	16.120	16.041	PhosphoSitePlus	CCLE	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q12772	SREBF2	P28482	MAPK1	S432	S436A	436	Missense	distal	4	no	15.410	15.317	EPSD;PhosphoSitePlus	CCLE	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q12772	SREBF2	P28482	MAPK1	S1046	R1049H	1049	Missense	distal	3	no	13.616	13.658	EPSD	CCLE	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P06401	PGR	P28482	MAPK1	S25	C29Y	29	Missense	distal	4	no	17.333	17.421	EPSD	CCLE	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P06401	PGR	P28482	MAPK1	S344	A348G	348	Missense	distal	4	no	9.114	9.158	EPSD	CCLE	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P06401	PGR	P28482	MAPK1	S345	A348G	348	Missense	distal	3	no	15.210	15.216	EPSD	CCLE	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P06401	PGR	P28482	MAPK1	T351	A348G	348	Missense	distal	-3	no	13.423	13.601	EPSD	CCLE	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P06401	PGR	P28482	MAPK1	S676	I681V	681	Missense	distal	5	no	14.149	14.324	EPSD	CCLE	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q15596	NCOA2	P28482	MAPK1	S29	D24E	24	Missense	distal	-5	no	14.576	14.531	EPSD	CCLE	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q15596	NCOA2	P28482	MAPK1	S554	S550L	550	Missense	distal	-4	no	14.431	14.211	EPSD	CCLE	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q15596	NCOA2	P28482	MAPK1	S655	P654S	654	Missense	proximal	-1	no	12.120	12.077	EPSD	CCLE	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q15596	NCOA2	P28482	MAPK1	S736	E733V	733	Missense	distal	-3	no	16.880	16.753	PhosphoSitePlus	CCLE	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P17676	CEBPB	P28482	MAPK1	S231	P236L	236	Missense	distal	5	no	14.407	14.193	EPSD	CCLE	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P17676	CEBPB	P28482	MAPK1	S231	P238L	238	Missense	distal	7	no	14.407	14.706	EPSD	CCLE	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P17676	CEBPB	P28482	MAPK1	T235	P236L	236	Missense	proximal	1	no	17.180	8.370	PhosphoSitePlus	CCLE	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P17676	CEBPB	P28482	MAPK1	T235	P238L	238	Missense	distal	3	no	17.180	17.269	PhosphoSitePlus	CCLE	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P17676	CEBPB	P28482	MAPK1	S237	P236L	236	Missense	proximal	-1	no	13.166	13.106	EPSD	CCLE	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P17676	CEBPB	P28482	MAPK1	S237	P238L	238	Missense	proximal	1	no	13.166	4.356	EPSD	CCLE	8.102	Loss
CMGC_MAPK_ERK1_MAPK1_ST	P05198	EIF2S1	P28482	MAPK1	S35	V34F	34	Missense	proximal	-1	no	8.704	8.640	EPSD	CCLE	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P05198	EIF2S1	P28482	MAPK1	S91	P92S	92	Missense	proximal	1	no	17.128	7.734	EPSD	CCLE	8.102	Loss
CMGC_MAPK_ERK1_MAPK1_ST	P05198	EIF2S1	P28482	MAPK1	S91	K97R	97	Missense	distal	6	no	17.128	16.964	EPSD	CCLE	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P05198	EIF2S1	P28482	MAPK1	S91	C98S	98	Missense	distal	7	no	17.128	16.469	EPSD	CCLE	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	O60504	SORBS3	P28482	MAPK1	S373	P374Q	374	Missense	proximal	1	no	13.044	4.550	EPSD	CCLE	8.102	Loss
CMGC_MAPK_ERK1_MAPK1_ST	O60504	SORBS3	P28482	MAPK1	S563	G560E	560	Missense	distal	-3	no	12.854	12.863	EPSD	CCLE	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q13480	GAB1	P28482	MAPK1	S454	M450T	450	Missense	distal	-4	no	16.090	16.242	EPSD	CCLE	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q13480	GAB1	P28482	MAPK1	S567	P568L	568	Missense	proximal	1	no	17.912	9.102	EPSD	CCLE	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	P10275	AR	P28482	MAPK1	S96	Q98R	98	Missense	proximal	2	no	11.382	11.674	EPSD	CCLE	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q14934	NFATC4	P28482	MAPK1	S168	S174N	174	Missense	distal	6	no	15.631	15.534	EPSD	CCLE	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q14934	NFATC4	P28482	MAPK1	S170	S174N	174	Missense	distal	4	no	14.021	13.983	EPSD	CCLE	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q14934	NFATC4	P28482	MAPK1	S217	S221F	221	Missense	distal	4	no	18.009	17.831	EPSD	CCLE	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q14934	NFATC4	P28482	MAPK1	S221	S221F	221	Missense	central	0	yes	13.632	0.000	EPSD	CCLE	8.102	Loss
CMGC_MAPK_ERK1_MAPK1_ST	Q14934	NFATC4	P28482	MAPK1	T226	S221F	221	Missense	distal	-5	no	17.136	17.224	EPSD	CCLE	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q14934	NFATC4	P28482	MAPK1	S592	A590T	590	Missense	proximal	-2	no	13.576	14.024	EPSD	CCLE	8.102	Up-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q14934	NFATC4	P28482	MAPK1	S716	P720L	720	Missense	distal	4	no	13.971	13.850	EPSD	CCLE	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q14934	NFATC4	P28482	MAPK1	S819	P820L	820	Missense	proximal	1	no	17.762	8.952	EPSD	CCLE	8.102	Down-regulation
CMGC_MAPK_ERK1_MAPK1_ST	Q9UPT5	EXOC7	P28482	MAPK1	S250	A252D	252	Missense	proximal	2	no	17.902	18.016	PhosphoSitePlus	CCLE	8.102	Up-regulation
CMGC_GSK_GSK3A_ST	P10636	MAPT	P49840	GSK3A	T101	G107V	107	Missense	distal	6	no	73.952	71.293	EPSD	CCLE	72.838	Loss
CMGC_GSK_GSK3A_ST	P10636	MAPT	P49840	GSK3A	T102	G107V	107	Missense	distal	5	no	76.454	73.955	EPSD	CCLE	72.838	Down-regulation
CMGC_GSK_GSK3A_ST	P10636	MAPT	P49840	GSK3A	T111	G107V	107	Missense	distal	-4	no	74.941	74.000	EPSD	CCLE	72.838	Down-regulation
CMGC_GSK_GSK3A_ST	P10636	MAPT	P49840	GSK3A	S171	P170F	170	Missense	proximal	-1	no	81.434	78.186	EPSD	CCLE	72.838	Down-regulation
CMGC_GSK_GSK3A_ST	P10636	MAPT	P49840	GSK3A	S171	G174A	174	Missense	distal	3	no	81.434	82.684	EPSD	CCLE	72.838	Up-regulation
CMGC_GSK_GSK3A_ST	P10636	MAPT	P49840	GSK3A	S227	D221Y	221	Missense	distal	-6	no	77.653	76.368	EPSD	CCLE	72.838	Down-regulation
CMGC_GSK_GSK3A_ST	P10636	MAPT	P49840	GSK3A	S227	P234S	234	Missense	distal	7	no	77.653	77.311	EPSD	CCLE	72.838	Down-regulation
CMGC_GSK_GSK3A_ST	P10636	MAPT	P49840	GSK3A	S228	D221Y	221	Missense	distal	-7	no	92.623	94.783	EPSD	CCLE	72.838	Up-regulation
CMGC_GSK_GSK3A_ST	P10636	MAPT	P49840	GSK3A	S228	P234S	234	Missense	distal	6	no	92.623	92.073	EPSD	CCLE	72.838	Down-regulation
CMGC_GSK_GSK3A_ST	P10636	MAPT	P49840	GSK3A	S232	P234S	234	Missense	proximal	2	no	85.793	85.104	EPSD	CCLE	72.838	Down-regulation
CMGC_GSK_GSK3A_ST	P10636	MAPT	P49840	GSK3A	S238	P234S	234	Missense	distal	-4	no	71.113	74.699	EPSD	CCLE	72.838	Gain
CMGC_GSK_GSK3A_ST	P10636	MAPT	P49840	GSK3A	S411	K405R	405	Missense	distal	-6	no	99.189	99.755	EPSD	CCLE	72.838	Up-regulation
CMGC_GSK_GSK3A_ST	P10636	MAPT	P49840	GSK3A	S437	V442I	442	Missense	distal	5	no	72.985	64.762	EPSD	CCLE	72.838	Loss
CMGC_GSK_GSK3A_ST	P10636	MAPT	P49840	GSK3A	S438	V442I	442	Missense	distal	4	no	99.970	101.476	EPSD	CCLE	72.838	Up-regulation
CMGC_GSK_GSK3A_ST	P10636	MAPT	P49840	GSK3A	S447	V442I	442	Missense	distal	-5	no	81.913	80.775	EPSD	CCLE	72.838	Down-regulation
CMGC_GSK_GSK3A_ST	P10636	MAPT	P49840	GSK3A	S508	R511H	511	Missense	distal	3	no	80.422	84.433	EPSD	CCLE	72.838	Up-regulation
CMGC_GSK_GSK3A_ST	P10636	MAPT	P49840	GSK3A	S512	R511H	511	Missense	proximal	-1	no	92.762	93.211	EPSD	CCLE	72.838	Up-regulation
CMGC_GSK_GSK3A_ST	P10636	MAPT	P49840	GSK3A	S512	G518S	518	Missense	distal	6	no	92.762	93.716	EPSD	CCLE	72.838	Up-regulation
CMGC_GSK_GSK3A_ST	P10636	MAPT	P49840	GSK3A	S515	R511H	511	Missense	distal	-4	no	88.526	91.490	EPSD	CCLE	72.838	Up-regulation
CMGC_GSK_GSK3A_ST	P10636	MAPT	P49840	GSK3A	S515	G518S	518	Missense	distal	3	no	88.526	89.133	EPSD	CCLE	72.838	Up-regulation
CMGC_GSK_GSK3A_ST	P10636	MAPT	P49840	GSK3A	S516	R511H	511	Missense	distal	-5	no	94.559	94.759	EPSD	CCLE	72.838	Up-regulation
CMGC_GSK_GSK3A_ST	P10636	MAPT	P49840	GSK3A	S516	G518S	518	Missense	proximal	2	no	94.559	95.990	EPSD	CCLE	72.838	Up-regulation
CMGC_GSK_GSK3A_ST	P10636	MAPT	P49840	GSK3A	S519	G518S	518	Missense	proximal	-1	no	91.776	91.801	EPSD	CCLE	72.838	Up-regulation
CMGC_GSK_GSK3A_ST	P10636	MAPT	P49840	GSK3A	S519	R526L	526	Missense	distal	7	no	91.776	91.690	EPSD	CCLE	72.838	Down-regulation
CMGC_GSK_GSK3A_ST	P10636	MAPT	P49840	GSK3A	T522	G518S	518	Missense	distal	-4	no	90.876	95.713	EPSD	CCLE	72.838	Up-regulation
CMGC_GSK_GSK3A_ST	P10636	MAPT	P49840	GSK3A	T522	R526L	526	Missense	distal	4	no	90.876	94.862	EPSD	CCLE	72.838	Up-regulation
CMGC_GSK_GSK3A_ST	P10636	MAPT	P49840	GSK3A	S525	G518S	518	Missense	distal	-7	no	84.428	84.234	EPSD	CCLE	72.838	Down-regulation
CMGC_GSK_GSK3A_ST	P10636	MAPT	P49840	GSK3A	S525	R526L	526	Missense	proximal	1	no	84.428	79.029	EPSD	CCLE	72.838	Down-regulation
CMGC_GSK_GSK3A_ST	P10636	MAPT	P49840	GSK3A	S527	R526L	526	Missense	proximal	-1	no	90.290	90.331	EPSD	CCLE	72.838	Up-regulation
CMGC_GSK_GSK3A_ST	P10636	MAPT	P49840	GSK3A	T529	R526L	526	Missense	distal	-3	no	77.055	76.203	EPSD	CCLE	72.838	Down-regulation
CMGC_GSK_GSK3A_ST	P10636	MAPT	P49840	GSK3A	S531	R526L	526	Missense	distal	-5	no	72.926	72.950	EPSD	CCLE	72.838	Up-regulation
CMGC_GSK_GSK3A_ST	P10636	MAPT	P49840	GSK3A	S552	R559H	559	Missense	distal	7	no	86.324	86.797	EPSD	CCLE	72.838	Up-regulation
CMGC_GSK_GSK3A_ST	P10636	MAPT	P49840	GSK3A	S555	R559H	559	Missense	distal	4	no	79.672	61.030	EPSD	CCLE	72.838	Loss
CMGC_GSK_GSK3A_ST	P10636	MAPT	P49840	GSK3A	S558	R559H	559	Missense	proximal	1	no	84.189	66.428	EPSD	CCLE	72.838	Loss
CMGC_GSK_GSK3A_ST	P10636	MAPT	P49840	GSK3A	S575	K574N	574	Missense	proximal	-1	no	72.897	73.267	EPSD	CCLE	72.838	Up-regulation
CMGC_GSK_GSK3A_ST	P10636	MAPT	P49840	GSK3A	S579	K574N	574	Missense	distal	-5	no	86.905	87.167	EPSD	CCLE	72.838	Up-regulation
CMGC_GSK_GSK3A_ST	P10636	MAPT	P49840	GSK3A	S713	G706V	706	Missense	distal	-7	no	88.443	88.333	EPSD	CCLE	72.838	Down-regulation
CMGC_GSK_GSK3A_ST	P10636	MAPT	P49840	GSK3A	S713	S717C	717	Missense	distal	4	no	88.443	15.030	EPSD	CCLE	72.838	Loss
CMGC_GSK_GSK3A_ST	P10636	MAPT	P49840	GSK3A	S717	S717C	717	Missense	central	0	yes	86.276	0.000	EPSD	CCLE	72.838	Loss
CMGC_GSK_GSK3A_ST	P10636	MAPT	P49840	GSK3A	S717	S721C	721	Missense	distal	4	no	86.276	12.863	EPSD	CCLE	72.838	Loss
CMGC_GSK_GSK3A_ST	P10636	MAPT	P49840	GSK3A	S717	H724R	724	Missense	distal	7	no	86.276	85.804	EPSD	CCLE	72.838	Down-regulation
CMGC_GSK_GSK3A_ST	P10636	MAPT	P49840	GSK3A	S721	S717C	717	Missense	distal	-4	no	89.833	65.754	EPSD	CCLE	72.838	Loss
CMGC_GSK_GSK3A_ST	P10636	MAPT	P49840	GSK3A	S721	S721C	721	Missense	central	0	yes	89.833	0.000	EPSD	CCLE	72.838	Loss
CMGC_GSK_GSK3A_ST	P10636	MAPT	P49840	GSK3A	S721	H724R	724	Missense	distal	3	no	89.833	85.821	EPSD	CCLE	72.838	Down-regulation
CMGC_GSK_GSK3A_ST	Q14449	GRB14	P49840	GSK3A	S358	G356D	356	Missense	proximal	-2	no	77.640	77.493	EPSD;PhosphoSitePlus	CCLE	72.838	Down-regulation
CMGC_GSK_GSK3A_ST	Q14449	GRB14	P49840	GSK3A	S358	Y354H	354	Missense	distal	-4	no	77.640	78.117	EPSD;PhosphoSitePlus	CCLE	72.838	Up-regulation
CMGC_GSK_GSK3A_ST	Q14449	GRB14	P49840	GSK3A	S362	G356D	356	Missense	distal	-6	no	81.324	82.344	PhosphoSitePlus;EPSD	CCLE	72.838	Up-regulation
CMGC_GSK_GSK3A_ST	Q8NHW3	MAFA	P49840	GSK3A	T53	P54S	54	Missense	proximal	1	no	92.645	76.953	EPSD;PhosphoSitePlus	CCLE	72.838	Down-regulation
CMGC_GSK_GSK3A_ST	Q8NHW3	MAFA	P49840	GSK3A	T57	P54S	54	Missense	distal	-3	no	75.822	75.182	EPSD;PhosphoSitePlus	CCLE	72.838	Down-regulation
CMGC_GSK_GSK3A_ST	Q8NHW3	MAFA	P49840	GSK3A	S61	P66S	66	Missense	distal	5	no	79.102	73.545	PhosphoSitePlus;EPSD	CCLE	72.838	Down-regulation
CMGC_GSK_GSK3A_ST	Q8NHW3	MAFA	P49840	GSK3A	S61	P54S	54	Missense	distal	-7	no	79.102	78.946	PhosphoSitePlus;EPSD	CCLE	72.838	Down-regulation
CMGC_GSK_GSK3A_ST	Q14596	NBR1	P49840	GSK3A	S123	V118L	118	Missense	distal	-5	no	86.314	85.449	EPSD	CCLE	72.838	Down-regulation
CMGC_GSK_GSK3A_ST	Q14596	NBR1	P49840	GSK3A	T586	V585M	585	Missense	proximal	-1	no	83.710	83.541	PhosphoSitePlus	CCLE	72.838	Down-regulation
CMGC_GSK_GSK3A_ST	P20749	BCL3	P49840	GSK3A	S41	P42L	42	Missense	proximal	1	no	76.510	62.459	EPSD	CCLE	72.838	Loss
CMGC_GSK_GSK3A_ST	P20749	BCL3	P49840	GSK3A	S382	R388H	388	Missense	distal	6	no	92.236	93.717	EPSD	CCLE	72.838	Up-regulation
CMGC_GSK_GSK3A_ST	P20749	BCL3	P49840	GSK3A	S385	R388H	388	Missense	distal	3	no	71.493	75.505	EPSD	CCLE	72.838	Gain
CMGC_GSK_GSK3A_ST	Q96F46	IL17RA	P49840	GSK3A	S726	V721L	721	Missense	distal	-5	no	83.451	82.586	EPSD	CCLE	72.838	Down-regulation
CMGC_GSK_GSK3A_ST	Q96F46	IL17RA	P49840	GSK3A	S726	S730N	730	Missense	distal	4	no	83.451	77.062	EPSD	CCLE	72.838	Down-regulation
CMGC_GSK_GSK3A_ST	Q96F46	IL17RA	P49840	GSK3A	T732	S730N	730	Missense	proximal	-2	no	80.376	79.490	EPSD	CCLE	72.838	Down-regulation
CMGC_GSK_GSK3A_ST	Q96F46	IL17RA	P49840	GSK3A	S736	S730N	730	Missense	distal	-6	no	74.091	74.679	EPSD	CCLE	72.838	Up-regulation
CMGC_GSK_GSK3A_ST	Q96F46	IL17RA	P49840	GSK3A	S829	D832H	832	Missense	distal	3	no	79.854	82.281	EPSD	CCLE	72.838	Up-regulation
CMGC_GSK_GSK3A_ST	P17661	DES	P49840	GSK3A	S81	A85T	85	Missense	distal	4	no	71.822	74.407	EPSD	CCLE	72.838	Gain
CMGC_GSK_GSK3A_ST	P35222	CTNNB1	P49840	GSK3A	T102	G106D	106	Missense	distal	4	no	64.604	77.799	EPSD	CCLE	72.838	Gain
CMGC_GSK_GSK3A_ST	P35222	CTNNB1	P49840	GSK3A	T112	G106D	106	Missense	distal	-6	no	71.986	73.007	EPSD	CCLE	72.838	Gain
CMGC_GSK_GSK3A_ST	P35222	CTNNB1	P49840	GSK3A	S196	T201P	201	Missense	distal	5	no	70.144	75.024	EPSD	CCLE	72.838	Gain
CMGC_GSK_GSK3A_ST	Q9Y6Q9	NCOA3	P49840	GSK3A	S777	E780Q	780	Missense	distal	3	no	74.236	70.964	EPSD	CCLE	72.838	Loss
CMGC_GSK_GSK3A_ST	Q9Y6Q9	NCOA3	P49840	GSK3A	S778	E780Q	780	Missense	proximal	2	no	78.542	77.544	EPSD	CCLE	72.838	Down-regulation
CMGC_GSK_GSK3A_ST	Q9Y6Q9	NCOA3	P49840	GSK3A	T912	T910A	910	Missense	proximal	-2	no	72.944	73.059	EPSD	CCLE	72.838	Up-regulation
CMGC_GSK_GSK3A_ST	Q92597	NDRG1	P49840	GSK3A	T350	S354F	354	Missense	distal	4	no	81.847	59.556	EPSD	CCLE	72.838	Loss
CMGC_GSK_GSK3A_ST	Q92597	NDRG1	P49840	GSK3A	S352	S354F	354	Missense	proximal	2	no	90.406	86.813	EPSD;PhosphoSitePlus	CCLE	72.838	Down-regulation
CMGC_GSK_GSK3A_ST	Q92597	NDRG1	P49840	GSK3A	T356	S354F	354	Missense	proximal	-2	no	82.016	80.797	EPSD	CCLE	72.838	Down-regulation
CMGC_GSK_GSK3A_ST	Q92597	NDRG1	P49840	GSK3A	S357	S354F	354	Missense	distal	-3	no	74.964	73.735	EPSD	CCLE	72.838	Down-regulation
CMGC_GSK_GSK3A_ST	Q92597	NDRG1	P49840	GSK3A	T360	S354F	354	Missense	distal	-6	no	78.647	80.278	EPSD	CCLE	72.838	Up-regulation
CMGC_GSK_GSK3A_ST	P31749	AKT1	P49840	GSK3A	T443	D439H	439	Missense	distal	-4	no	75.141	76.417	EPSD	CCLE	72.838	Up-regulation
CMGC_GSK_GSK3A_ST	O75030	MITF	P49840	GSK3A	S55	I48L	48	Missense	distal	-7	no	75.212	74.334	EPSD	CCLE	72.838	Down-regulation
CMGC_GSK_GSK3A_ST	O75030	MITF	P49840	GSK3A	S176	G174R	174	Missense	proximal	-2	no	73.322	74.424	EPSD	CCLE	72.838	Up-regulation
CMGC_GSK_GSK3A_ST	O75030	MITF	P49840	GSK3A	S180	G174R	174	Missense	distal	-6	no	76.843	77.000	EPSD	CCLE	72.838	Up-regulation
CMGC_GSK_GSK3A_ST	O75030	MITF	P49840	GSK3A	S491	S491F	491	Missense	central	0	yes	78.972	0.000	EPSD	CCLE	72.838	Loss
CMGC_GSK_GSK3A_ST	O75030	MITF	P49840	GSK3A	S508	S512N	512	Missense	distal	4	no	81.179	74.790	EPSD	CCLE	72.838	Down-regulation
CMGC_GSK_GSK3A_ST	Q6R327	RICTOR	P49840	GSK3A	S1121	K1119E	1119	Missense	proximal	-2	no	73.112	71.751	EPSD	CCLE	72.838	Loss
CMGC_GSK_GSK3A_ST	Q6R327	RICTOR	P49840	GSK3A	S1124	K1119E	1119	Missense	distal	-5	no	81.810	81.920	EPSD	CCLE	72.838	Up-regulation
CMGC_GSK_GSK3A_ST	Q6R327	RICTOR	P49840	GSK3A	S1353	E1349K	1349	Missense	distal	-4	no	76.756	74.962	EPSD	CCLE	72.838	Down-regulation
CMGC_GSK_GSK3A_ST	Q6R327	RICTOR	P49840	GSK3A	T1361	T1365I	1365	Missense	distal	4	no	73.757	70.184	EPSD	CCLE	72.838	Loss
CMGC_GSK_GSK3A_ST	Q6R327	RICTOR	P49840	GSK3A	S1581	S1587G	1587	Missense	distal	6	no	74.501	73.548	EPSD	CCLE	72.838	Down-regulation
CMGC_GSK_GSK3A_ST	Q6R327	RICTOR	P49840	GSK3A	T1589	S1587G	1587	Missense	proximal	-2	no	73.203	72.464	EPSD	CCLE	72.838	Loss
CMGC_GSK_GSK3A_ST	P01106	MYC	P49840	GSK3A	T58	E54K	54	Missense	distal	-4	no	93.334	91.540	PhosphoSitePlus	CCLE	72.838	Down-regulation
CMGC_GSK_GSK3A_ST	P01106	MYC	P49840	GSK3A	T58	P57H	57	Missense	proximal	-1	no	93.334	92.587	PhosphoSitePlus	CCLE	72.838	Down-regulation
CMGC_GSK_GSK3A_ST	P01106	MYC	P49840	GSK3A	S62	P57H	57	Missense	distal	-5	no	79.709	78.322	EPSD	CCLE	72.838	Down-regulation
CMGC_GSK_GSK3A_ST	P01106	MYC	P49840	GSK3A	S62	L69I	69	Missense	distal	7	no	79.709	80.225	EPSD	CCLE	72.838	Up-regulation
CMGC_GSK_GSK3A_ST	P01106	MYC	P49840	GSK3A	S67	L69I	69	Missense	proximal	2	no	91.781	89.433	EPSD	CCLE	72.838	Down-regulation
CMGC_GSK_GSK3A_ST	P01106	MYC	P49840	GSK3A	S67	Y74S	74	Missense	distal	7	no	91.781	91.706	EPSD	CCLE	72.838	Down-regulation
CMGC_GSK_GSK3A_ST	P01106	MYC	P49840	GSK3A	S71	L69I	69	Missense	proximal	-2	no	88.696	88.528	EPSD	CCLE	72.838	Down-regulation
CMGC_GSK_GSK3A_ST	P01106	MYC	P49840	GSK3A	S71	Y74S	74	Missense	distal	3	no	88.696	84.801	EPSD	CCLE	72.838	Down-regulation
CMGC_GSK_GSK3A_ST	P01106	MYC	P49840	GSK3A	S71	T78R	78	Missense	distal	7	no	88.696	87.574	EPSD	CCLE	72.838	Down-regulation
CMGC_GSK_GSK3A_ST	P01106	MYC	P49840	GSK3A	T78	Y74S	74	Missense	distal	-4	no	75.225	76.106	EPSD	CCLE	72.838	Up-regulation
CMGC_GSK_GSK3A_ST	P01106	MYC	P49840	GSK3A	T78	T78R	78	Missense	central	0	yes	75.225	0.000	EPSD	CCLE	72.838	Loss
CMGC_GSK_GSK3A_ST	P01106	MYC	P49840	GSK3A	T78	L82F	82	Missense	distal	4	no	75.225	58.344	EPSD	CCLE	72.838	Loss
CMGC_GSK_GSK3A_ST	P01106	MYC	P49840	GSK3A	S151	Q153R	153	Missense	proximal	2	no	82.900	83.499	EPSD	CCLE	72.838	Up-regulation
CMGC_GSK_GSK3A_ST	P01106	MYC	P49840	GSK3A	S159	Q153R	153	Missense	distal	-6	no	72.973	73.315	EPSD	CCLE	72.838	Up-regulation
CMGC_GSK_GSK3A_ST	P01106	MYC	P49840	GSK3A	S172	C171W	171	Missense	proximal	-1	no	81.732	82.462	EPSD	CCLE	72.838	Up-regulation
CMGC_GSK_GSK3A_ST	P01106	MYC	P49840	GSK3A	S172	Y177H	177	Missense	distal	5	no	81.732	76.445	EPSD	CCLE	72.838	Down-regulation
CMGC_GSK_GSK3A_ST	P01106	MYC	P49840	GSK3A	S249	S252C	252	Missense	distal	3	no	75.277	70.963	EPSD	CCLE	72.838	Loss
CMGC_GSK_GSK3A_ST	Q07817	BCL2L1	P49840	GSK3A	S62	S62N	62	Missense	central	0	yes	89.682	0.000	PhosphoSitePlus	CCLE	72.838	Loss
CMGC_GSK_GSK3A_ST	Q9Y4H4	GPSM3	P49840	GSK3A	S74	R76H	76	Missense	proximal	2	no	75.614	74.777	EPSD	CCLE	72.838	Down-regulation
CMGC_GSK_GSK3A_ST	Q9NZ72	STMN3	P49840	GSK3A	S60	E67Q	67	Missense	distal	7	no	87.763	87.254	PhosphoSitePlus	CCLE	72.838	Down-regulation
CMGC_GSK_GSK3A_ST	Q9NZ72	STMN3	P49840	GSK3A	S65	E67Q	67	Missense	proximal	2	no	73.156	72.158	EPSD	CCLE	72.838	Loss
CMGC_GSK_GSK3A_ST	Q9NZ72	STMN3	P49840	GSK3A	S68	E67Q	67	Missense	proximal	-1	no	77.617	77.445	EPSD	CCLE	72.838	Down-regulation
CMGC_GSK_GSK3A_ST	Q9NZ72	STMN3	P49840	GSK3A	S73	E67Q	67	Missense	distal	-6	no	86.291	86.720	EPSD	CCLE	72.838	Up-regulation
Atypical_PDHK_PDHK_PDK2_ST	P08559	PDHA1	Q15119	PDK2	S232	A236V	236	Missense	distal	4	no	4.198	4.109	EPSD;PhosphoSitePlus	CCLE	1.129	Down-regulation
Atypical_PDHK_PDHK_PDK2_ST	P08559	PDHA1	Q15119	PDK2	T240	A236V	236	Missense	distal	-4	no	1.294	1.295	EPSD	CCLE	1.129	Up-regulation
Atypical_PDHK_PDHK_PDK2_ST	P29803	PDHA2	Q15119	PDK2	S230	G228E	228	Missense	proximal	-2	no	2.450	1.914	EPSD	CCLE	1.129	Down-regulation
Atypical_PDHK_PDHK_PDK2_ST	P29803	PDHA2	Q15119	PDK2	T284	H288Y	288	Missense	distal	4	no	1.160	1.116	EPSD	CCLE	1.129	Loss
Atypical_PDHK_PDHK_PDK2_ST	P29803	PDHA2	Q15119	PDK2	T284	H288R	288	Missense	distal	4	no	1.160	1.195	EPSD	CCLE	1.129	Up-regulation
Atypical_PDHK_PDHK_PDK2_ST	P29803	PDHA2	Q15119	PDK2	S291	H288Y	288	Missense	distal	-3	no	4.883	4.880	EPSD;PhosphoSitePlus	CCLE	1.129	Down-regulation
Atypical_PDHK_PDHK_PDK2_ST	P29803	PDHA2	Q15119	PDK2	S291	H288R	288	Missense	distal	-3	no	4.883	4.882	EPSD;PhosphoSitePlus	CCLE	1.129	Down-regulation
TK_Met_MET_Y	P09874	PARP1	P08581	MET	Y907	D914N	914	Missense	distal	7	no	35.103	34.958	PhosphoSitePlus	CCLE	27.257	Down-regulation
TK_Met_MET_Y	Q04912	MST1R	P08581	MET	Y1353	L1356V	1356	Missense	distal	3	no	46.732	51.416	PhosphoSitePlus;EPSD	CCLE	27.257	Up-regulation
TK_Met_MET_Y	Q04912	MST1R	P08581	MET	Y1353	V1354M	1354	Missense	proximal	1	no	46.732	47.764	PhosphoSitePlus;EPSD	CCLE	27.257	Up-regulation
TK_Met_MET_Y	Q04912	MST1R	P08581	MET	Y1360	L1356V	1356	Missense	distal	-4	no	30.446	32.907	EPSD;PhosphoSitePlus	CCLE	27.257	Up-regulation
TK_Met_MET_Y	Q04912	MST1R	P08581	MET	Y1360	V1354M	1354	Missense	distal	-6	no	30.446	30.110	EPSD;PhosphoSitePlus	CCLE	27.257	Down-regulation
TK_Met_MET_Y	P35568	IRS1	P08581	MET	Y582	V577M	577	Missense	distal	-5	no	26.809	27.826	EPSD	CCLE	27.257	Gain
TK_Met_MET_Y	P35568	IRS1	P08581	MET	Y732	V738M	738	Missense	distal	6	no	36.487	38.624	EPSD	CCLE	27.257	Up-regulation
TK_Met_MET_Y	P35568	IRS1	P08581	MET	Y750	S747A	747	Missense	distal	-3	no	54.834	50.077	EPSD	CCLE	27.257	Down-regulation
TK_Met_MET_Y	P35568	IRS1	P08581	MET	Y764	L767V	767	Missense	distal	3	no	31.418	36.101	EPSD	CCLE	27.257	Up-regulation
TK_Met_MET_Y	P35568	IRS1	P08581	MET	Y765	L767V	767	Missense	proximal	2	no	29.558	30.325	EPSD	CCLE	27.257	Up-regulation
TK_Met_MET_Y	P35568	IRS1	P08581	MET	Y941	K943N	943	Missense	proximal	2	no	35.701	35.830	EPSD	CCLE	27.257	Up-regulation
TK_Met_MET_Y	Q05397	PTK2	P08581	MET	Y5	P8S	8	Missense	distal	3	no	33.030	24.697	EPSD;PhosphoSitePlus	CCLE	27.257	Loss
TK_Met_MET_Y	P06213	INSR	P08581	MET	Y1011	C1008S	1008	Missense	distal	-3	no	25.300	38.202	EPSD	CCLE	27.257	Gain
CMGC_DYRK_DYRK1_DYRK1A_ST	P10636	MAPT	Q13627	DYRK1A	S64	A66V	66	Missense	proximal	2	no	41.642	40.472	EPSD	CCLE	34.163	Down-regulation
CMGC_DYRK_DYRK1_DYRK1A_ST	P10636	MAPT	Q13627	DYRK1A	T69	A66V	66	Missense	distal	-3	no	44.531	49.676	EPSD	CCLE	34.163	Up-regulation
CMGC_DYRK_DYRK1_DYRK1A_ST	P10636	MAPT	Q13627	DYRK1A	T111	G107V	107	Missense	distal	-4	no	49.672	49.661	EPSD	CCLE	34.163	Down-regulation
CMGC_DYRK_DYRK1_DYRK1A_ST	P10636	MAPT	Q13627	DYRK1A	T167	G174A	174	Missense	distal	7	no	34.037	35.668	EPSD	CCLE	34.163	Gain
CMGC_DYRK_DYRK1_DYRK1A_ST	P10636	MAPT	Q13627	DYRK1A	S171	P170F	170	Missense	proximal	-1	no	40.913	42.722	EPSD	CCLE	34.163	Up-regulation
CMGC_DYRK_DYRK1_DYRK1A_ST	P10636	MAPT	Q13627	DYRK1A	S171	G174A	174	Missense	distal	3	no	40.913	40.983	EPSD	CCLE	34.163	Up-regulation
CMGC_DYRK_DYRK1_DYRK1A_ST	P10636	MAPT	Q13627	DYRK1A	T173	P170F	170	Missense	distal	-3	no	40.645	24.244	EPSD	CCLE	34.163	Loss
CMGC_DYRK_DYRK1_DYRK1A_ST	P10636	MAPT	Q13627	DYRK1A	T173	G174A	174	Missense	proximal	1	no	40.645	25.099	EPSD	CCLE	34.163	Loss
CMGC_DYRK_DYRK1_DYRK1A_ST	P10636	MAPT	Q13627	DYRK1A	S214	D221Y	221	Missense	distal	7	no	45.770	46.674	EPSD	CCLE	34.163	Up-regulation
CMGC_DYRK_DYRK1_DYRK1A_ST	P10636	MAPT	Q13627	DYRK1A	S228	D221Y	221	Missense	distal	-7	no	47.818	48.590	EPSD	CCLE	34.163	Up-regulation
CMGC_DYRK_DYRK1_DYRK1A_ST	P10636	MAPT	Q13627	DYRK1A	S228	P234S	234	Missense	distal	6	no	47.818	47.827	EPSD	CCLE	34.163	Up-regulation
CMGC_DYRK_DYRK1_DYRK1A_ST	P10636	MAPT	Q13627	DYRK1A	S235	P234S	234	Missense	proximal	-1	no	46.531	46.352	EPSD	CCLE	34.163	Down-regulation
CMGC_DYRK_DYRK1_DYRK1A_ST	P10636	MAPT	Q13627	DYRK1A	S235	D242H	242	Missense	distal	7	no	46.531	46.345	EPSD	CCLE	34.163	Down-regulation
CMGC_DYRK_DYRK1_DYRK1A_ST	P10636	MAPT	Q13627	DYRK1A	S238	P234S	234	Missense	distal	-4	no	39.382	39.384	EPSD	CCLE	34.163	Up-regulation
CMGC_DYRK_DYRK1_DYRK1A_ST	P10636	MAPT	Q13627	DYRK1A	S238	D242H	242	Missense	distal	4	no	39.382	37.965	EPSD	CCLE	34.163	Down-regulation
CMGC_DYRK_DYRK1_DYRK1A_ST	P10636	MAPT	Q13627	DYRK1A	S411	K405R	405	Missense	distal	-6	no	40.744	41.142	EPSD	CCLE	34.163	Up-regulation
CMGC_DYRK_DYRK1_DYRK1A_ST	P10636	MAPT	Q13627	DYRK1A	S438	V442I	442	Missense	distal	4	no	58.880	59.316	EPSD	CCLE	34.163	Up-regulation
CMGC_DYRK_DYRK1_DYRK1A_ST	P10636	MAPT	Q13627	DYRK1A	S508	R511H	511	Missense	distal	3	no	42.149	41.990	EPSD	CCLE	34.163	Down-regulation
CMGC_DYRK_DYRK1_DYRK1A_ST	P10636	MAPT	Q13627	DYRK1A	S516	R511H	511	Missense	distal	-5	no	52.447	51.097	EPSD	CCLE	34.163	Down-regulation
CMGC_DYRK_DYRK1_DYRK1A_ST	P10636	MAPT	Q13627	DYRK1A	S516	G518S	518	Missense	proximal	2	no	52.447	51.987	EPSD	CCLE	34.163	Down-regulation
CMGC_DYRK_DYRK1_DYRK1A_ST	P10636	MAPT	Q13627	DYRK1A	S519	G518S	518	Missense	proximal	-1	no	55.503	54.931	EPSD	CCLE	34.163	Down-regulation
CMGC_DYRK_DYRK1_DYRK1A_ST	P10636	MAPT	Q13627	DYRK1A	S519	R526L	526	Missense	distal	7	no	55.503	58.638	EPSD	CCLE	34.163	Up-regulation
CMGC_DYRK_DYRK1_DYRK1A_ST	P10636	MAPT	Q13627	DYRK1A	T522	G518S	518	Missense	distal	-4	no	56.470	56.491	EPSD	CCLE	34.163	Up-regulation
CMGC_DYRK_DYRK1_DYRK1A_ST	P10636	MAPT	Q13627	DYRK1A	T522	R526L	526	Missense	distal	4	no	56.470	59.470	EPSD	CCLE	34.163	Up-regulation
CMGC_DYRK_DYRK1_DYRK1A_ST	P10636	MAPT	Q13627	DYRK1A	T529	R526L	526	Missense	distal	-3	no	56.569	43.214	EPSD	CCLE	34.163	Down-regulation
CMGC_DYRK_DYRK1_DYRK1A_ST	P10636	MAPT	Q13627	DYRK1A	S552	R559H	559	Missense	distal	7	no	58.137	61.161	EPSD	CCLE	34.163	Up-regulation
CMGC_DYRK_DYRK1_DYRK1A_ST	P10636	MAPT	Q13627	DYRK1A	S558	R559H	559	Missense	proximal	1	no	43.216	11.054	EPSD	CCLE	34.163	Loss
CMGC_DYRK_DYRK1_DYRK1A_ST	P10636	MAPT	Q13627	DYRK1A	S637	D631E	631	Missense	distal	-6	no	35.842	36.464	EPSD	CCLE	34.163	Up-regulation
CMGC_DYRK_DYRK1_DYRK1A_ST	P10636	MAPT	Q13627	DYRK1A	T703	G706V	706	Missense	distal	3	no	34.910	34.578	EPSD	CCLE	34.163	Down-regulation
CMGC_DYRK_DYRK1_DYRK1A_ST	P10636	MAPT	Q13627	DYRK1A	S713	G706V	706	Missense	distal	-7	no	54.587	55.844	EPSD	CCLE	34.163	Up-regulation
CMGC_DYRK_DYRK1_DYRK1A_ST	P10636	MAPT	Q13627	DYRK1A	S713	S717C	717	Missense	distal	4	no	54.587	55.841	EPSD	CCLE	34.163	Up-regulation
CMGC_DYRK_DYRK1_DYRK1A_ST	P10636	MAPT	Q13627	DYRK1A	S721	S717C	717	Missense	distal	-4	no	52.410	52.397	EPSD	CCLE	34.163	Down-regulation
CMGC_DYRK_DYRK1_DYRK1A_ST	P10636	MAPT	Q13627	DYRK1A	S721	S721C	721	Missense	central	0	yes	52.410	0.000	EPSD	CCLE	34.163	Loss
CMGC_DYRK_DYRK1_DYRK1A_ST	P10636	MAPT	Q13627	DYRK1A	S721	H724R	724	Missense	distal	3	no	52.410	52.570	EPSD	CCLE	34.163	Up-regulation
CMGC_DYRK_DYRK1_DYRK1A_ST	P10636	MAPT	Q13627	DYRK1A	S739	Q741K	741	Missense	proximal	2	no	49.406	49.603	EPSD	CCLE	34.163	Up-regulation
CMGC_DYRK_DYRK1_DYRK1A_ST	P49418	AMPH	Q13627	DYRK1A	S293	R298W	298	Missense	distal	5	no	65.700	61.898	EPSD;PhosphoSitePlus	CCLE	34.163	Down-regulation
CMGC_DYRK_DYRK1_DYRK1A_ST	P49418	AMPH	Q13627	DYRK1A	S293	P294H	294	Missense	proximal	1	no	65.700	18.457	EPSD;PhosphoSitePlus	CCLE	34.163	Loss
CMGC_DYRK_DYRK1_DYRK1A_ST	P49418	AMPH	Q13627	DYRK1A	S295	R298W	298	Missense	distal	3	no	53.995	53.802	EPSD;PhosphoSitePlus	CCLE	34.163	Down-regulation
CMGC_DYRK_DYRK1_DYRK1A_ST	P49418	AMPH	Q13627	DYRK1A	S295	P294H	294	Missense	proximal	-1	no	53.995	54.119	EPSD;PhosphoSitePlus	CCLE	34.163	Up-regulation
CMGC_DYRK_DYRK1_DYRK1A_ST	P24928	POLR2A	Q13627	DYRK1A	S27	E30K	30	Missense	distal	3	no	52.809	52.796	EPSD	CCLE	34.163	Down-regulation
CMGC_DYRK_DYRK1_DYRK1A_ST	P24928	POLR2A	Q13627	DYRK1A	S35	E30K	30	Missense	distal	-5	no	46.038	46.612	EPSD	CCLE	34.163	Up-regulation
CMGC_DYRK_DYRK1_DYRK1A_ST	P24928	POLR2A	Q13627	DYRK1A	T857	R863W	863	Missense	distal	6	no	36.096	36.213	EPSD	CCLE	34.163	Up-regulation
CMGC_DYRK_DYRK1_DYRK1A_ST	P24928	POLR2A	Q13627	DYRK1A	S1571	P1567L	1567	Missense	distal	-4	no	38.122	38.120	EPSD	CCLE	34.163	Down-regulation
CMGC_DYRK_DYRK1_DYRK1A_ST	P24928	POLR2A	Q13627	DYRK1A	S1574	P1567L	1567	Missense	distal	-7	no	45.919	46.921	EPSD	CCLE	34.163	Up-regulation
CMGC_DYRK_DYRK1_DYRK1A_ST	P24928	POLR2A	Q13627	DYRK1A	S1616	S1616Y	1616	Missense	central	0	yes	50.699	0.000	PhosphoSitePlus;EPSD	CCLE	34.163	Loss
CMGC_DYRK_DYRK1_DYRK1A_ST	P24928	POLR2A	Q13627	DYRK1A	S1619	S1616Y	1616	Missense	distal	-3	no	51.765	42.368	EPSD;PhosphoSitePlus	CCLE	34.163	Down-regulation
CMGC_DYRK_DYRK1_DYRK1A_ST	P24928	POLR2A	Q13627	DYRK1A	S1654	T1660P	1660	Missense	distal	6	no	34.740	34.743	EPSD	CCLE	34.163	Up-regulation
CMGC_DYRK_DYRK1_DYRK1A_ST	P24928	POLR2A	Q13627	DYRK1A	S1661	T1660P	1660	Missense	proximal	-1	no	38.237	38.886	EPSD	CCLE	34.163	Up-regulation
CMGC_DYRK_DYRK1_DYRK1A_ST	P24928	POLR2A	Q13627	DYRK1A	S1710	Y1713S	1713	Missense	distal	3	no	37.504	37.923	EPSD	CCLE	34.163	Up-regulation
CMGC_DYRK_DYRK1_DYRK1A_ST	P24928	POLR2A	Q13627	DYRK1A	S1717	Y1713S	1713	Missense	distal	-4	no	39.858	39.888	EPSD	CCLE	34.163	Up-regulation
CMGC_DYRK_DYRK1_DYRK1A_ST	P24928	POLR2A	Q13627	DYRK1A	S1766	Y1762H	1762	Missense	distal	-4	no	36.827	36.854	EPSD	CCLE	34.163	Up-regulation
CMGC_DYRK_DYRK1_DYRK1A_ST	P24928	POLR2A	Q13627	DYRK1A	T1854	K1859R	1859	Missense	distal	5	no	40.096	40.140	EPSD	CCLE	34.163	Up-regulation
CMGC_DYRK_DYRK1_DYRK1A_ST	P24928	POLR2A	Q13627	DYRK1A	S1861	K1859R	1859	Missense	proximal	-2	no	37.943	42.375	EPSD	CCLE	34.163	Up-regulation
CMGC_DYRK_DYRK1_DYRK1A_ST	P24928	POLR2A	Q13627	DYRK1A	S1864	K1859R	1859	Missense	distal	-5	no	45.115	46.280	EPSD	CCLE	34.163	Up-regulation
CMGC_DYRK_DYRK1_DYRK1A_ST	P24928	POLR2A	Q13627	DYRK1A	S1889	T1894S	1894	Missense	distal	5	no	43.194	41.710	EPSD	CCLE	34.163	Down-regulation
CMGC_DYRK_DYRK1_DYRK1A_ST	P24928	POLR2A	Q13627	DYRK1A	S1892	T1894S	1894	Missense	proximal	2	no	39.918	40.177	EPSD	CCLE	34.163	Up-regulation
CMGC_DYRK_DYRK1_DYRK1A_ST	P24928	POLR2A	Q13627	DYRK1A	S1896	T1894S	1894	Missense	proximal	-2	no	37.561	37.861	EPSD	CCLE	34.163	Up-regulation
CMGC_DYRK_DYRK1_DYRK1A_ST	P24928	POLR2A	Q13627	DYRK1A	S1899	T1894S	1894	Missense	distal	-5	no	42.757	43.095	EPSD	CCLE	34.163	Up-regulation
CMGC_DYRK_DYRK1_DYRK1A_ST	P24928	POLR2A	Q13627	DYRK1A	S1899	P1904S	1904	Missense	distal	5	no	42.757	42.818	EPSD	CCLE	34.163	Up-regulation
CMGC_DYRK_DYRK1_DYRK1A_ST	P24928	POLR2A	Q13627	DYRK1A	T1903	P1904S	1904	Missense	proximal	1	no	42.295	20.342	EPSD	CCLE	34.163	Loss
CMGC_DYRK_DYRK1_DYRK1A_ST	P24928	POLR2A	Q13627	DYRK1A	S1910	P1904S	1904	Missense	distal	-6	no	35.690	36.393	EPSD	CCLE	34.163	Up-regulation
CMGC_DYRK_DYRK1_DYRK1A_ST	P24928	POLR2A	Q13627	DYRK1A	S1910	P1914L	1914	Missense	distal	4	no	35.690	37.737	EPSD	CCLE	34.163	Up-regulation
CMGC_DYRK_DYRK1_DYRK1A_ST	P24928	POLR2A	Q13627	DYRK1A	S1913	P1914L	1914	Missense	proximal	1	no	40.178	-2.153	EPSD	CCLE	34.163	Loss
CMGC_DYRK_DYRK1_DYRK1A_ST	P24928	POLR2A	Q13627	DYRK1A	S1917	P1914L	1914	Missense	distal	-3	no	40.222	38.229	EPSD	CCLE	34.163	Down-regulation
CMGC_DYRK_DYRK1_DYRK1A_ST	P24928	POLR2A	Q13627	DYRK1A	S1920	P1914L	1914	Missense	distal	-6	no	37.826	37.883	EPSD	CCLE	34.163	Up-regulation
CMGC_DYRK_DYRK1_DYRK1A_ST	P24928	POLR2A	Q13627	DYRK1A	S1934	S1941F	1941	Missense	distal	7	no	42.628	46.025	EPSD	CCLE	34.163	Up-regulation
CMGC_DYRK_DYRK1_DYRK1A_ST	P24928	POLR2A	Q13627	DYRK1A	T1939	S1941F	1941	Missense	proximal	2	no	39.329	37.943	EPSD	CCLE	34.163	Down-regulation
CMGC_DYRK_DYRK1_DYRK1A_ST	P24928	POLR2A	Q13627	DYRK1A	T1939	S1944Y	1944	Missense	distal	5	no	39.329	34.686	EPSD	CCLE	34.163	Down-regulation
CMGC_DYRK_DYRK1_DYRK1A_ST	P24928	POLR2A	Q13627	DYRK1A	S1941	S1941F	1941	Missense	central	0	yes	36.377	0.000	EPSD	CCLE	34.163	Loss
CMGC_DYRK_DYRK1_DYRK1A_ST	P24928	POLR2A	Q13627	DYRK1A	S1941	S1944Y	1944	Missense	distal	3	no	36.377	35.958	EPSD	CCLE	34.163	Down-regulation
CMGC_DYRK_DYRK1_DYRK1A_ST	P24928	POLR2A	Q13627	DYRK1A	S1944	S1941F	1941	Missense	distal	-3	no	50.754	31.582	EPSD	CCLE	34.163	Loss
CMGC_DYRK_DYRK1_DYRK1A_ST	P24928	POLR2A	Q13627	DYRK1A	S1944	S1944Y	1944	Missense	central	0	yes	50.754	0.000	EPSD	CCLE	34.163	Loss
CMGC_DYRK_DYRK1_DYRK1A_ST	P24928	POLR2A	Q13627	DYRK1A	S1948	S1941F	1941	Missense	distal	-7	no	34.639	35.741	EPSD	CCLE	34.163	Up-regulation
CMGC_DYRK_DYRK1_DYRK1A_ST	P24928	POLR2A	Q13627	DYRK1A	S1948	S1944Y	1944	Missense	distal	-4	no	34.639	34.609	EPSD	CCLE	34.163	Down-regulation
CMGC_DYRK_DYRK1_DYRK1A_ST	P24928	POLR2A	Q13627	DYRK1A	S1948	P1952A	1952	Missense	distal	4	no	34.639	35.297	EPSD	CCLE	34.163	Up-regulation
CMGC_DYRK_DYRK1_DYRK1A_ST	P24928	POLR2A	Q13627	DYRK1A	S1951	S1944Y	1944	Missense	distal	-7	no	46.557	48.101	EPSD	CCLE	34.163	Up-regulation
CMGC_DYRK_DYRK1_DYRK1A_ST	P24928	POLR2A	Q13627	DYRK1A	S1951	P1952A	1952	Missense	proximal	1	no	46.557	16.412	EPSD	CCLE	34.163	Loss
CMGC_DYRK_DYRK1_DYRK1A_ST	P08151	GLI1	Q13627	DYRK1A	S408	S410F	410	Missense	proximal	2	no	54.087	52.701	PhosphoSitePlus	CCLE	34.163	Down-regulation
CMGC_DYRK_DYRK1_DYRK1A_ST	P08151	GLI1	Q13627	DYRK1A	S545	I549S	549	Missense	distal	4	no	47.505	44.633	EPSD	CCLE	34.163	Down-regulation
CMGC_DYRK_DYRK1_DYRK1A_ST	P08151	GLI1	Q13627	DYRK1A	S640	A645T	645	Missense	distal	5	no	43.812	45.674	EPSD	CCLE	34.163	Up-regulation
CMGC_DYRK_DYRK1_DYRK1A_ST	Q13627	DYRK1A	Q13627	DYRK1A	S758	P759H	759	Missense	proximal	1	no	37.400	-9.843	EPSD	CCLE	34.163	Loss
CMGC_DYRK_DYRK1_DYRK1A_ST	O95644	NFATC1	Q13627	DYRK1A	S117	R119L	119	Missense	proximal	2	no	35.943	35.042	EPSD	CCLE	34.163	Down-regulation
CMGC_DYRK_DYRK1_DYRK1A_ST	O95644	NFATC1	Q13627	DYRK1A	S117	T123N	123	Missense	distal	6	no	35.943	35.955	EPSD	CCLE	34.163	Up-regulation
CMGC_DYRK_DYRK1_DYRK1A_ST	O95644	NFATC1	Q13627	DYRK1A	S172	S176I	176	Missense	distal	4	no	32.320	35.192	EPSD	CCLE	34.163	Gain
CMGC_DYRK_DYRK1_DYRK1A_ST	O95644	NFATC1	Q13627	DYRK1A	S178	S179P	179	Missense	proximal	1	no	15.770	37.723	EPSD	CCLE	34.163	Gain
CMGC_DYRK_DYRK1_DYRK1A_ST	O95644	NFATC1	Q13627	DYRK1A	S237	R235Q	235	Missense	proximal	-2	no	54.613	50.434	EPSD	CCLE	34.163	Down-regulation
CMGC_DYRK_DYRK1_DYRK1A_ST	O95644	NFATC1	Q13627	DYRK1A	S237	R243C	243	Missense	distal	6	no	54.613	54.759	EPSD	CCLE	34.163	Up-regulation
CMGC_DYRK_DYRK1_DYRK1A_ST	O95644	NFATC1	Q13627	DYRK1A	S241	S245I	245	Missense	distal	4	no	31.597	34.470	EPSD	CCLE	34.163	Gain
CMGC_DYRK_DYRK1_DYRK1A_ST	O95644	NFATC1	Q13627	DYRK1A	S245	R243C	243	Missense	proximal	-2	no	35.442	22.322	EPSD	CCLE	34.163	Loss
CMGC_DYRK_DYRK1_DYRK1A_ST	O95644	NFATC1	Q13627	DYRK1A	S245	S245I	245	Missense	central	0	yes	35.442	0.000	EPSD	CCLE	34.163	Loss
CMGC_DYRK_DYRK1_DYRK1A_ST	O95644	NFATC1	Q13627	DYRK1A	S261	N264S	264	Missense	distal	3	no	56.111	56.521	PhosphoSitePlus;EPSD	CCLE	34.163	Up-regulation
CMGC_DYRK_DYRK1_DYRK1A_ST	O95644	NFATC1	Q13627	DYRK1A	S278	R273W	273	Missense	distal	-5	no	55.224	52.967	EPSD;PhosphoSitePlus	CCLE	34.163	Down-regulation
CMGC_DYRK_DYRK1_DYRK1A_ST	O95644	NFATC1	Q13627	DYRK1A	T284	P287S	287	Missense	distal	3	no	41.433	41.954	EPSD	CCLE	34.163	Up-regulation
CMGC_DYRK_DYRK1_DYRK1A_ST	O95644	NFATC1	Q13627	DYRK1A	S286	P287S	287	Missense	proximal	1	no	38.820	16.867	EPSD	CCLE	34.163	Loss
CMGC_DYRK_DYRK1_DYRK1A_ST	O95644	NFATC1	Q13627	DYRK1A	S403	Y407C	407	Missense	distal	4	no	53.664	53.281	EPSD;PhosphoSitePlus	CCLE	34.163	Down-regulation
CMGC_DYRK_DYRK1_DYRK1A_ST	O95644	NFATC1	Q13627	DYRK1A	S409	Y407C	407	Missense	proximal	-2	no	52.496	44.665	EPSD;PhosphoSitePlus	CCLE	34.163	Down-regulation
CMGC_DYRK_DYRK1_DYRK1A_ST	O95644	NFATC1	Q13627	DYRK1A	S670	V672A	672	Missense	proximal	2	no	38.408	39.579	EPSD	CCLE	34.163	Up-regulation
CMGC_DYRK_DYRK1_DYRK1A_ST	O95644	NFATC1	Q13627	DYRK1A	S670	H673R	673	Missense	distal	3	no	38.408	38.568	EPSD	CCLE	34.163	Up-regulation
CMGC_DYRK_DYRK1_DYRK1A_ST	O95644	NFATC1	Q13627	DYRK1A	S670	S675G	675	Missense	distal	5	no	38.408	39.634	EPSD	CCLE	34.163	Up-regulation
CMGC_DYRK_DYRK1_DYRK1A_ST	O95644	NFATC1	Q13627	DYRK1A	S772	T777P	777	Missense	distal	5	no	38.864	37.319	EPSD	CCLE	34.163	Down-regulation
CMGC_DYRK_DYRK1_DYRK1A_ST	O95644	NFATC1	Q13627	DYRK1A	S903	I909M	909	Missense	distal	6	no	34.217	34.201	EPSD	CCLE	34.163	Down-regulation
CMGC_DYRK_DYRK1_DYRK1A_ST	O95644	NFATC1	Q13627	DYRK1A	T912	I909M	909	Missense	distal	-3	no	37.004	32.976	EPSD	CCLE	34.163	Loss
CMGC_DYRK_DYRK1_DYRK1A_ST	O75533	SF3B1	Q13627	DYRK1A	S541	L536I	536	Missense	distal	-5	no	36.901	37.314	EPSD	CCLE	34.163	Up-regulation
CMGC_DYRK_DYRK1_DYRK1A_ST	O75533	SF3B1	Q13627	DYRK1A	S1271	K1267N	1267	Missense	distal	-4	no	43.021	43.047	EPSD	CCLE	34.163	Up-regulation
CMGC_DYRK_DYRK1_DYRK1A_ST	Q96S94	CCNL2	Q13627	DYRK1A	S25	G31R	31	Missense	distal	6	no	41.427	41.432	EPSD	CCLE	34.163	Up-regulation
CMGC_DYRK_DYRK1_DYRK1A_ST	Q96S94	CCNL2	Q13627	DYRK1A	S32	G31R	31	Missense	proximal	-1	no	43.486	42.562	EPSD	CCLE	34.163	Down-regulation
CMGC_DYRK_DYRK1_DYRK1A_ST	Q96S94	CCNL2	Q13627	DYRK1A	S369	K376N	376	Missense	distal	7	no	54.235	55.376	EPSD;PhosphoSitePlus	CCLE	34.163	Up-regulation
CMGC_DYRK_DYRK1_DYRK1A_ST	Q96S94	CCNL2	Q13627	DYRK1A	S394	P395T	395	Missense	proximal	1	no	38.187	15.810	EPSD	CCLE	34.163	Loss
CMGC_DYRK_DYRK1_DYRK1A_ST	Q96S94	CCNL2	Q13627	DYRK1A	S400	P395T	395	Missense	distal	-5	no	53.626	52.533	EPSD	CCLE	34.163	Down-regulation
CMGC_DYRK_DYRK1_DYRK1A_ST	Q96S94	CCNL2	Q13627	DYRK1A	S427	Q431R	431	Missense	distal	4	no	57.911	55.656	EPSD	CCLE	34.163	Down-regulation
CMGC_DYRK_DYRK1_DYRK1A_ST	Q52LA3	LIN52	Q13627	DYRK1A	T51	S48R	48	Missense	distal	-3	no	26.351	34.940	EPSD	CCLE	34.163	Gain
CMGC_DYRK_DYRK1_DYRK1A_ST	Q52LA3	LIN52	Q13627	DYRK1A	S53	S48R	48	Missense	distal	-5	no	46.625	47.855	EPSD	CCLE	34.163	Up-regulation
CMGC_DYRK_DYRK1_DYRK1A_ST	P04637	TP53	Q13627	DYRK1A	S33	E28Q	28	Missense	distal	-5	no	34.790	35.375	EPSD	CCLE	34.163	Up-regulation
CMGC_DYRK_DYRK1_DYRK1A_ST	Q12778	FOXO1	Q13627	DYRK1A	S329	S325T	325	Missense	distal	-4	no	54.730	54.738	PhosphoSitePlus	CCLE	34.163	Up-regulation
CMGC_DYRK_DYRK1_DYRK1A_ST	Q12778	FOXO1	Q13627	DYRK1A	S430	M431V	431	Missense	proximal	1	no	-4.086	40.290	EPSD	CCLE	34.163	Gain
CMGC_DYRK_DYRK1_DYRK1A_ST	Q12778	FOXO1	Q13627	DYRK1A	S470	I476L	476	Missense	distal	6	no	37.884	37.777	EPSD	CCLE	34.163	Down-regulation
CMGC_DYRK_DYRK1_DYRK1A_ST	O76039	CDKL5	Q13627	DYRK1A	S377	G373A	373	Missense	distal	-4	no	37.916	37.944	EPSD	CCLE	34.163	Up-regulation
CMGC_DYRK_DYRK1_DYRK1A_ST	O76039	CDKL5	Q13627	DYRK1A	S377	Y384C	384	Missense	distal	7	no	37.916	37.538	EPSD	CCLE	34.163	Down-regulation
CMGC_DYRK_DYRK1_DYRK1A_ST	O76039	CDKL5	Q13627	DYRK1A	S407	H404P	404	Missense	distal	-3	no	41.725	45.695	EPSD	CCLE	34.163	Up-regulation
CMGC_DYRK_DYRK1_DYRK1A_ST	O76039	CDKL5	Q13627	DYRK1A	S529	T533A	533	Missense	distal	4	no	51.791	51.577	EPSD	CCLE	34.163	Down-regulation
CMGC_DYRK_DYRK1_DYRK1A_ST	O76039	CDKL5	Q13627	DYRK1A	T531	T533A	533	Missense	proximal	2	no	36.608	37.169	EPSD	CCLE	34.163	Up-regulation
CMGC_DYRK_DYRK1_DYRK1A_ST	O76039	CDKL5	Q13627	DYRK1A	S987	C988R	988	Missense	proximal	1	no	21.029	37.321	EPSD	CCLE	34.163	Gain
CMGC_DYRK_DYRK1_DYRK1A_ST	Q05193	DNM1	Q13627	DYRK1A	S795	V788E	788	Missense	distal	-7	no	55.882	54.376	EPSD	CCLE	34.163	Down-regulation
CMGC_DYRK_DYRK1_DYRK1A_ST	Q05193	DNM1	Q13627	DYRK1A	S822	P816S	816	Missense	distal	-6	no	39.170	39.873	EPSD	CCLE	34.163	Up-regulation
CMGC_DYRK_HIPK_HIPK1_ST	P51608	MECP2	Q86Z02	HIPK1	S178	P173A	173	Missense	distal	-5	no	4.226	4.342	EPSD	CCLE	1.785	Up-regulation
CMGC_DYRK_HIPK_HIPK1_ST	P51608	MECP2	Q86Z02	HIPK1	S216	K223N	223	Missense	distal	7	no	7.998	7.985	PhosphoSitePlus;EPSD	CCLE	1.785	Down-regulation
CMGC_DYRK_HIPK_HIPK1_ST	P51608	MECP2	Q86Z02	HIPK1	S229	G231E	231	Missense	proximal	2	no	3.042	2.992	EPSD	CCLE	1.785	Down-regulation
CMGC_DYRK_HIPK_HIPK1_ST	P51608	MECP2	Q86Z02	HIPK1	S229	K223N	223	Missense	distal	-6	no	3.042	2.853	EPSD	CCLE	1.785	Down-regulation
CMGC_DYRK_HIPK_HIPK1_ST	P51608	MECP2	Q86Z02	HIPK1	S350	R344W	344	Missense	distal	-6	no	2.272	2.178	EPSD	CCLE	1.785	Down-regulation
CMGC_DYRK_HIPK_HIPK1_ST	P51608	MECP2	Q86Z02	HIPK1	S396	P393A	393	Missense	distal	-3	no	3.015	3.131	EPSD	CCLE	1.785	Up-regulation
CMGC_DYRK_HIPK_HIPK1_ST	P51608	MECP2	Q86Z02	HIPK1	S411	S410R	410	Missense	proximal	-1	no	2.343	2.389	EPSD	CCLE	1.785	Up-regulation
CMGC_DYRK_HIPK_HIPK1_ST	P51608	MECP2	Q86Z02	HIPK1	S411	S409N	409	Missense	proximal	-2	no	2.343	2.106	EPSD	CCLE	1.785	Down-regulation
CMGC_DYRK_HIPK_HIPK1_ST	P51608	MECP2	Q86Z02	HIPK1	T479	R478W	478	Missense	proximal	-1	no	3.273	3.202	EPSD	CCLE	1.785	Down-regulation
Other_NEK_NEK11_NEK11_ST	P54132	BLM	Q8NG66	NEK11	S48	N46S	46	Missense	proximal	-2	no	3.483	3.475	EPSD	CCLE	2.788	Down-regulation
Other_NEK_NEK11_NEK11_ST	P54132	BLM	Q8NG66	NEK11	S168	T162I	162	Missense	distal	-6	no	3.481	3.516	EPSD	CCLE	2.788	Up-regulation
Other_NEK_NEK11_NEK11_ST	P54132	BLM	Q8NG66	NEK11	S315	I309F	309	Missense	distal	-6	no	3.222	3.207	EPSD	CCLE	2.788	Down-regulation
Other_NEK_NEK11_NEK11_ST	P54132	BLM	Q8NG66	NEK11	S539	N541Y	541	Missense	proximal	2	no	3.884	3.714	EPSD	CCLE	2.788	Down-regulation
Other_NEK_NEK11_NEK11_ST	P54132	BLM	Q8NG66	NEK11	S539	R545S	545	Missense	distal	6	no	3.884	3.948	EPSD	CCLE	2.788	Up-regulation
TK_Jak_JAK2_Y	P62993	GRB2	O60674	JAK2	Y52	Y52N	52	Missense	central	0	yes	9.250	0.000	EPSD;PhosphoSitePlus	CCLE	5.995	Loss
TK_Jak_JAK2_Y	Q13153	PAK1	O60674	JAK2	Y201	E195Q	195	Missense	distal	-6	no	8.459	8.627	EPSD;PhosphoSitePlus	CCLE	5.995	Up-regulation
TK_Jak_JAK2_Y	Q13153	PAK1	O60674	JAK2	Y201	P194L	194	Missense	distal	-7	no	8.459	8.455	EPSD;PhosphoSitePlus	CCLE	5.995	Down-regulation
TK_Jak_JAK2_Y	Q13153	PAK1	O60674	JAK2	Y285	T292I	292	Missense	distal	7	no	9.010	8.873	PhosphoSitePlus;EPSD	CCLE	5.995	Down-regulation
TK_Jak_JAK2_Y	Q9UGK3	STAP2	O60674	JAK2	Y22	E27Q	27	Missense	distal	5	no	7.962	7.267	EPSD;PhosphoSitePlus	CCLE	5.995	Down-regulation
TK_Jak_JAK2_Y	Q9UGK3	STAP2	O60674	JAK2	Y250	Y250N	250	Missense	central	0	yes	11.373	0.000	PhosphoSitePlus;EPSD	CCLE	5.995	Loss
TK_Jak_JAK2_Y	Q9UGK3	STAP2	O60674	JAK2	Y310	E307Q	307	Missense	distal	-3	no	9.636	11.806	EPSD;PhosphoSitePlus	CCLE	5.995	Up-regulation
TK_Jak_JAK2_Y	O60674	JAK2	O60674	JAK2	Y221	R228P	228	Missense	distal	7	no	11.172	11.137	EPSD	CCLE	5.995	Down-regulation
TK_Jak_JAK2_Y	O60674	JAK2	O60674	JAK2	Y382	A377E	377	Missense	distal	-5	no	6.018	6.074	EPSD	CCLE	5.995	Up-regulation
TK_Jak_JAK2_Y	Q15910	EZH2	O60674	JAK2	Y641	F637S	637	Missense	distal	-4	no	9.471	9.756	PhosphoSitePlus	CCLE	5.995	Up-regulation
TK_Jak_JAK2_Y	P28482	MAPK1	O60674	JAK2	Y43	V46L	46	Missense	distal	3	no	5.441	6.618	EPSD	CCLE	5.995	Gain
TK_Jak_JAK2_Y	Q15118	PDK1	O60674	JAK2	Y243	Y243H	243	Missense	central	0	yes	9.334	0.000	PhosphoSitePlus	CCLE	5.995	Loss
TK_Jak_JAK2_Y	Q15118	PDK1	O60674	JAK2	Y243	N246H	246	Missense	distal	3	no	9.334	9.703	PhosphoSitePlus	CCLE	5.995	Up-regulation
TK_Jak_JAK2_Y	Q15118	PDK1	O60674	JAK2	Y268	P263T	263	Missense	distal	-5	no	6.139	6.249	EPSD	CCLE	5.995	Up-regulation
TK_Jak_JAK2_Y	Q15118	PDK1	O60674	JAK2	Y403	L400I	400	Missense	distal	-3	no	6.722	9.103	EPSD	CCLE	5.995	Up-regulation
TK_Jak_JAK2_Y	Q99683	MAP3K5	O60674	JAK2	Y718	S716N	716	Missense	proximal	-2	no	10.831	10.889	PhosphoSitePlus	CCLE	5.995	Up-regulation
CMGC_CDK_CDK4_CDK4_ST	Q8IZL8	PELP1	P11802	CDK4	T647	P654T	654	Missense	distal	7	no	9.108	9.101	EPSD	CCLE	2.642	Down-regulation
CMGC_CDK_CDK4_CDK4_ST	Q8IZL8	PELP1	P11802	CDK4	T647	P653R	653	Missense	distal	6	no	9.108	9.154	EPSD	CCLE	2.642	Up-regulation
CMGC_CDK_CDK4_CDK4_ST	Q8IZL8	PELP1	P11802	CDK4	S658	P664S	664	Missense	distal	6	no	7.514	7.671	EPSD	CCLE	2.642	Up-regulation
CMGC_CDK_CDK4_CDK4_ST	Q8IZL8	PELP1	P11802	CDK4	S658	P653R	653	Missense	distal	-5	no	7.514	7.542	EPSD	CCLE	2.642	Up-regulation
CMGC_CDK_CDK4_CDK4_ST	Q8IZL8	PELP1	P11802	CDK4	S743	I750M	750	Missense	distal	7	no	2.730	2.734	EPSD	CCLE	2.642	Up-regulation
CMGC_CDK_CDK4_CDK4_ST	Q8IZL8	PELP1	P11802	CDK4	T745	P752Q	752	Missense	distal	7	no	8.700	8.689	EPSD	CCLE	2.642	Down-regulation
CMGC_CDK_CDK4_CDK4_ST	Q8IZL8	PELP1	P11802	CDK4	T745	I750M	750	Missense	distal	5	no	8.700	8.693	EPSD	CCLE	2.642	Down-regulation
CMGC_CDK_CDK4_CDK4_ST	Q8IZL8	PELP1	P11802	CDK4	S804	P802Q	802	Missense	proximal	-2	no	2.648	2.167	EPSD	CCLE	2.642	Loss
CMGC_CDK_CDK4_CDK4_ST	Q8IZL8	PELP1	P11802	CDK4	T807	P802Q	802	Missense	distal	-5	no	9.033	9.057	EPSD	CCLE	2.642	Up-regulation
CMGC_CDK_CDK4_CDK4_ST	Q8IZL8	PELP1	P11802	CDK4	S1043	E1042K	1042	Missense	proximal	-1	no	8.513	8.422	EPSD	CCLE	2.642	Down-regulation
CMGC_CDK_CDK4_CDK4_ST	P06400	RB1	P11802	CDK4	T373	M379T	379	Missense	distal	6	no	7.816	7.881	EPSD;PhosphoSitePlus	CCLE	2.642	Up-regulation
CMGC_CDK_CDK4_CDK4_ST	P06400	RB1	P11802	CDK4	S608	P609H	609	Missense	proximal	1	no	8.292	1.710	EPSD;PhosphoSitePlus	CCLE	2.642	Loss
CMGC_CDK_CDK4_CDK4_ST	P06400	RB1	P11802	CDK4	S612	P609H	609	Missense	distal	-3	no	8.583	8.805	EPSD;PhosphoSitePlus	CCLE	2.642	Up-regulation
CMGC_CDK_CDK4_CDK4_ST	Q08999	RBL2	P11802	CDK4	S40	D33N	33	Missense	distal	-7	no	8.516	8.662	EPSD	CCLE	2.642	Up-regulation
CMGC_CDK_CDK4_CDK4_ST	Q08999	RBL2	P11802	CDK4	S40	P43L	43	Missense	distal	3	no	8.516	7.617	EPSD	CCLE	2.642	Down-regulation
CMGC_CDK_CDK4_CDK4_ST	Q08999	RBL2	P11802	CDK4	T42	P43L	43	Missense	proximal	1	no	6.730	-0.850	EPSD	CCLE	2.642	Loss
CMGC_CDK_CDK4_CDK4_ST	Q08999	RBL2	P11802	CDK4	S639	I634L	634	Missense	distal	-5	no	6.454	6.439	EPSD	CCLE	2.642	Down-regulation
CMGC_CDK_CDK4_CDK4_ST	Q08999	RBL2	P11802	CDK4	S662	T665A	665	Missense	distal	3	no	7.975	8.136	EPSD	CCLE	2.642	Up-regulation
CMGC_CDK_CDK4_CDK4_ST	Q08999	RBL2	P11802	CDK4	S671	T665A	665	Missense	distal	-6	no	2.809	2.722	EPSD	CCLE	2.642	Down-regulation
CMGC_CDK_CDK4_CDK4_ST	Q08999	RBL2	P11802	CDK4	S672	T665A	665	Missense	distal	-7	no	7.567	7.761	EPSD;PhosphoSitePlus	CCLE	2.642	Up-regulation
CMGC_CDK_CDK4_CDK4_ST	Q08999	RBL2	P11802	CDK4	S1080	F1077C	1077	Missense	distal	-3	no	7.198	7.225	EPSD	CCLE	2.642	Up-regulation
CMGC_CDK_CDK4_CDK4_ST	Q08050	FOXM1	P11802	CDK4	S331	L334S	334	Missense	distal	3	no	8.282	8.876	EPSD	CCLE	2.642	Up-regulation
CMGC_CDK_CDK4_CDK4_ST	Q08050	FOXM1	P11802	CDK4	S331	D328E	328	Missense	distal	-3	no	8.282	8.218	EPSD	CCLE	2.642	Down-regulation
CMGC_CDK_CDK4_CDK4_ST	Q08050	FOXM1	P11802	CDK4	S489	S493Y	493	Missense	distal	4	no	8.526	8.835	EPSD;PhosphoSitePlus	CCLE	2.642	Up-regulation
CMGC_CDK_CDK4_CDK4_ST	Q08050	FOXM1	P11802	CDK4	S508	K514N	514	Missense	distal	6	no	9.538	9.490	EPSD;PhosphoSitePlus	CCLE	2.642	Down-regulation
CMGC_CDK_CDK4_CDK4_ST	Q08050	FOXM1	P11802	CDK4	T510	K514N	514	Missense	distal	4	no	8.407	8.457	PhosphoSitePlus;EPSD	CCLE	2.642	Up-regulation
CMGC_CDK_CDK4_CDK4_ST	Q12778	FOXO1	P11802	CDK4	S318	S325T	325	Missense	distal	7	no	3.323	3.307	EPSD	CCLE	2.642	Down-regulation
CMGC_CDK_CDK4_CDK4_ST	Q12778	FOXO1	P11802	CDK4	S329	S325T	325	Missense	distal	-4	no	8.621	8.622	EPSD	CCLE	2.642	Up-regulation
CMGC_CDK_CDK4_CDK4_ST	Q12778	FOXO1	P11802	CDK4	S432	M431V	431	Missense	proximal	-1	no	8.212	8.239	EPSD	CCLE	2.642	Up-regulation
CMGC_CDK_CDK4_CDK4_ST	Q12778	FOXO1	P11802	CDK4	S470	I476L	476	Missense	distal	6	no	8.382	8.400	EPSD	CCLE	2.642	Up-regulation
CMGC_CDK_CDK4_CDK4_ST	Q12778	FOXO1	P11802	CDK4	T478	I476L	476	Missense	proximal	-2	no	6.760	6.765	EPSD	CCLE	2.642	Up-regulation
CMGC_CDK_CDK4_CDK4_ST	P84022	SMAD3	P11802	CDK4	T179	P177A	177	Missense	proximal	-2	no	8.331	7.931	EPSD;PhosphoSitePlus	CCLE	2.642	Down-regulation
CMGC_CDK_CDK4_CDK4_ST	P84022	SMAD3	P11802	CDK4	T179	P180L	180	Missense	proximal	1	no	8.331	0.751	EPSD;PhosphoSitePlus	CCLE	2.642	Loss
CMGC_CDK_CDK4_CDK4_ST	P26358	DNMT1	P11802	CDK4	T137	T137R	137	Missense	central	0	yes	7.575	0.000	EPSD	CCLE	2.642	Loss
CMGC_CDK_CDK4_CDK4_ST	P26358	DNMT1	P11802	CDK4	T328	K335R	335	Missense	distal	7	no	6.601	6.598	EPSD	CCLE	2.642	Down-regulation
CMGC_CDK_CDK4_CDK4_ST	P26358	DNMT1	P11802	CDK4	T328	T333M	333	Missense	distal	5	no	6.601	6.612	EPSD	CCLE	2.642	Up-regulation
CMGC_CDK_CDK4_CDK4_ST	P26358	DNMT1	P11802	CDK4	S1105	P1099S	1099	Missense	distal	-6	no	7.262	7.052	EPSD	CCLE	2.642	Down-regulation
CMGC_CDK_CDK4_CDK4_ST	Q14814	MEF2D	P11802	CDK4	S180	P181S	181	Missense	proximal	1	no	7.159	0.972	EPSD	CCLE	2.642	Loss
CMGC_CDK_CDK4_CDK4_ST	Q14814	MEF2D	P11802	CDK4	S190	P196S	196	Missense	distal	6	no	2.789	2.947	EPSD	CCLE	2.642	Up-regulation
CMGC_CDK_CDK4_CDK4_ST	Q14814	MEF2D	P11802	CDK4	S192	P196S	196	Missense	distal	4	no	8.333	8.126	EPSD	CCLE	2.642	Down-regulation
CMGC_CDK_CDK4_CDK4_ST	Q14814	MEF2D	P11802	CDK4	S242	L243P	243	Missense	proximal	1	no	-0.108	7.471	EPSD	CCLE	2.642	Gain
CMGC_CDK_CDK4_CDK4_ST	Q14814	MEF2D	P11802	CDK4	S444	V443A	443	Missense	proximal	-1	no	10.359	10.122	EPSD	CCLE	2.642	Down-regulation
CMGC_CDK_CDK4_CDK4_ST	Q14814	MEF2D	P11802	CDK4	S444	I438N	438	Missense	distal	-6	no	10.359	10.204	EPSD	CCLE	2.642	Down-regulation
CMGC_CDK_CDK4_CDK4_ST	Q14814	MEF2D	P11802	CDK4	S450	V443A	443	Missense	distal	-7	no	7.572	8.058	EPSD	CCLE	2.642	Up-regulation
CMGC_CDK_CDK4_CDK4_ST	Q14814	MEF2D	P11802	CDK4	S472	A474S	474	Missense	proximal	2	no	8.018	8.117	EPSD	CCLE	2.642	Up-regulation
CMGC_CDK_CDK4_CDK4_ST	P38398	BRCA1	P11802	CDK4	T967	L973F	973	Missense	distal	6	no	7.182	7.137	EPSD	CCLE	2.642	Down-regulation
CMGC_CDK_CDK4_CDK4_ST	P38398	BRCA1	P11802	CDK4	S1551	D1557N	1557	Missense	distal	6	no	3.482	3.536	EPSD	CCLE	2.642	Up-regulation
CMGC_CDK_CDK4_CDK4_ST	P38398	BRCA1	P11802	CDK4	S1613	E1609D	1609	Missense	distal	-4	no	8.365	8.366	EPSD	CCLE	2.642	Up-regulation
CMGC_CDK_CDK4_CDK4_ST	Q96KS0	EGLN2	P11802	CDK4	S130	P129H	129	Missense	proximal	-1	no	6.672	6.717	PhosphoSitePlus	CCLE	2.642	Up-regulation
CMGC_CDK_CDK4_CDK4_ST	P15923	TCF3	P11802	CDK4	S55	L50F	50	Missense	distal	-5	no	2.813	2.799	EPSD	CCLE	2.642	Down-regulation
CMGC_CDK_CDK4_CDK4_ST	P15923	TCF3	P11802	CDK4	S244	P238T	238	Missense	distal	-6	no	3.540	3.517	EPSD	CCLE	2.642	Down-regulation
CMGC_CDK_CDK4_CDK4_ST	P15923	TCF3	P11802	CDK4	S245	P238T	238	Missense	distal	-7	no	9.863	9.654	PhosphoSitePlus;EPSD	CCLE	2.642	Down-regulation
CMGC_CDK_CDK4_CDK4_ST	P15923	TCF3	P11802	CDK4	S253	G254S	254	Missense	proximal	1	no	4.675	4.289	EPSD	CCLE	2.642	Down-regulation
CMGC_CDK_CDK4_CDK4_ST	P15923	TCF3	P11802	CDK4	S294	S294F	294	Missense	central	0	yes	2.991	0.000	EPSD	CCLE	2.642	Loss
CMGC_CDK_CDK4_CDK4_ST	P15923	TCF3	P11802	CDK4	S294	L287F	287	Missense	distal	-7	no	2.991	2.959	EPSD	CCLE	2.642	Down-regulation
CMGC_CDK_CDK4_CDK4_ST	P15923	TCF3	P11802	CDK4	S306	V304I	304	Missense	proximal	-2	no	2.964	2.957	EPSD	CCLE	2.642	Down-regulation
CMGC_CDK_CDK4_CDK4_ST	P15923	TCF3	P11802	CDK4	S341	S345L	345	Missense	distal	4	no	6.916	7.284	EPSD	CCLE	2.642	Up-regulation
CMGC_CDK_CDK4_CDK4_ST	P15923	TCF3	P11802	CDK4	S351	S345L	345	Missense	distal	-6	no	2.564	2.926	EPSD	CCLE	2.642	Gain
CMGC_CDK_CDK4_CDK4_ST	P15923	TCF3	P11802	CDK4	S352	S345L	345	Missense	distal	-7	no	8.901	8.220	EPSD	CCLE	2.642	Down-regulation
CMGC_CDK_CDK4_CDK4_ST	P15923	TCF3	P11802	CDK4	S379	A377V	377	Missense	proximal	-2	no	8.806	8.678	EPSD	CCLE	2.642	Down-regulation
CMGC_CDK_CDK4_CDK4_ST	P15923	TCF3	P11802	CDK4	S379	A374D	374	Missense	distal	-5	no	8.806	8.714	EPSD	CCLE	2.642	Down-regulation
CMGC_CDK_CDK4_CDK4_ST	P15923	TCF3	P11802	CDK4	T508	E501D	501	Missense	distal	-7	no	2.885	2.655	EPSD	CCLE	2.642	Down-regulation
CMGC_CDK_CDK4_CDK4_ST	Q9BQA1	WDR77	P11802	CDK4	T5	L9P	9	Missense	distal	4	no	8.687	8.526	EPSD;PhosphoSitePlus	CCLE	2.642	Down-regulation
CMGC_CDK_CDK4_CDK4_ST	Q92830	KAT2A	P11802	CDK4	T9	S5F	5	Missense	distal	-4	no	7.199	7.200	EPSD	CCLE	2.642	Up-regulation
CMGC_CDK_CDK4_CDK4_ST	Q92830	KAT2A	P11802	CDK4	S33	T27I	27	Missense	distal	-6	no	7.601	7.780	EPSD	CCLE	2.642	Up-regulation
CMGC_CDK_CDK4_CDK4_ST	Q92830	KAT2A	P11802	CDK4	S415	L419P	419	Missense	distal	4	no	3.333	3.173	EPSD	CCLE	2.642	Down-regulation
CMGC_CDK_CDK4_CDK4_ST	P46527	CDKN1B	P11802	CDK4	S10	S12I	12	Missense	proximal	2	no	7.994	7.718	EPSD	CCLE	2.642	Down-regulation
CMGC_CDK_CDK4_CDK4_ST	P21333	FLNA	P11802	CDK4	S468	V463M	463	Missense	distal	-5	no	8.346	8.361	EPSD	CCLE	2.642	Up-regulation
CMGC_CDK_CDK4_CDK4_ST	P21333	FLNA	P11802	CDK4	S1084	Q1078R	1078	Missense	distal	-6	no	7.951	7.946	EPSD	CCLE	2.642	Down-regulation
CMGC_CDK_CDK4_CDK4_ST	P21333	FLNA	P11802	CDK4	S1906	T1913I	1913	Missense	distal	7	no	3.069	3.059	EPSD	CCLE	2.642	Down-regulation
CMGC_CDK_CDK4_CDK4_ST	Q13761	RUNX3	P11802	CDK4	S71	T69P	69	Missense	proximal	-2	no	7.041	7.462	EPSD	CCLE	2.642	Up-regulation
CMGC_CDK_CDK4_CDK4_ST	Q13761	RUNX3	P11802	CDK4	T209	L204P	204	Missense	distal	-5	no	7.556	7.571	EPSD	CCLE	2.642	Up-regulation
CMGC_CDK_CDK4_CDK4_ST	Q13761	RUNX3	P11802	CDK4	S214	T221P	221	Missense	distal	7	no	7.185	7.193	EPSD	CCLE	2.642	Up-regulation
CMGC_CDK_CDK4_CDK4_ST	Q13761	RUNX3	P11802	CDK4	S220	T221P	221	Missense	proximal	1	no	1.680	8.207	EPSD	CCLE	2.642	Gain
CMGC_CDK_CDK4_CDK4_ST	P04637	TP53	P11802	CDK4	S33	E28Q	28	Missense	distal	-5	no	7.064	7.030	EPSD	CCLE	2.642	Down-regulation
CMGC_CDK_CDK4_CDK4_ST	P28749	RBL1	P11802	CDK4	T369	R374W	374	Missense	distal	5	no	7.842	7.859	EPSD;PhosphoSitePlus	CCLE	2.642	Up-regulation
CMGC_CDK_CDK4_CDK4_ST	P28749	RBL1	P11802	CDK4	S629	M636I	636	Missense	distal	7	no	3.690	3.686	EPSD	CCLE	2.642	Down-regulation
CMGC_CDK_CDK4_CDK4_ST	P28749	RBL1	P11802	CDK4	S749	L753R	753	Missense	distal	4	no	7.445	7.308	EPSD	CCLE	2.642	Down-regulation
CMGC_CDK_CDK4_CDK4_ST	P43694	GATA4	P11802	CDK4	S105	Y99C	99	Missense	distal	-6	no	9.149	9.228	PhosphoSitePlus	CCLE	2.642	Up-regulation
STE_STE11_MEKK2_MAP3K3_ST	P08151	GLI1	Q99759	MAP3K3	S201	P202H	202	Missense	proximal	1	no	29.891	25.859	PhosphoSitePlus;EPSD	CCLE	11.002	Down-regulation
STE_STE11_MEKK2_MAP3K3_ST	P08151	GLI1	Q99759	MAP3K3	S201	G206C	206	Missense	distal	5	no	29.891	30.097	PhosphoSitePlus;EPSD	CCLE	11.002	Up-regulation
STE_STE11_MEKK2_MAP3K3_ST	P08151	GLI1	Q99759	MAP3K3	S204	P202H	202	Missense	proximal	-2	no	28.536	27.448	EPSD;PhosphoSitePlus	CCLE	11.002	Down-regulation
STE_STE11_MEKK2_MAP3K3_ST	P08151	GLI1	Q99759	MAP3K3	S204	G206C	206	Missense	proximal	2	no	28.536	29.118	EPSD;PhosphoSitePlus	CCLE	11.002	Up-regulation
TKL_STKR_STKR1_TGFBR1_ST	Q03167	TGFBR3	P36897	TGFBR1	S651	E657Q	657	Missense	distal	6	no	14.135	13.043	EPSD	CCLE	13.873	Loss
TKL_STKR_STKR1_TGFBR1_ST	Q03167	TGFBR3	P36897	TGFBR1	S651	N646S	646	Missense	distal	-5	no	14.135	14.058	EPSD	CCLE	13.873	Down-regulation
TKL_STKR_STKR1_TGFBR1_ST	Q15796	SMAD2	P36897	TGFBR1	S110	R114H	114	Missense	distal	4	no	13.969	14.109	EPSD	CCLE	13.873	Up-regulation
TKL_STKR_STKR1_TGFBR1_ST	Q15796	SMAD2	P36897	TGFBR1	S118	R120P	120	Missense	proximal	2	no	16.204	16.092	EPSD	CCLE	13.873	Down-regulation
TKL_STKR_STKR1_TGFBR1_ST	Q15796	SMAD2	P36897	TGFBR1	S118	R114H	114	Missense	distal	-4	no	16.204	16.061	EPSD	CCLE	13.873	Down-regulation
TKL_STKR_STKR1_TGFBR1_ST	Q15796	SMAD2	P36897	TGFBR1	S250	L254F	254	Missense	distal	4	no	15.150	15.233	EPSD	CCLE	13.873	Up-regulation
TKL_STKR_STKR1_TGFBR1_ST	Q15796	SMAD2	P36897	TGFBR1	S260	L254F	254	Missense	distal	-6	no	14.690	15.443	EPSD	CCLE	13.873	Up-regulation
TKL_STKR_STKR1_TGFBR1_ST	P68104	EEF1A1	P36897	TGFBR1	S354	P350L	350	Missense	distal	-4	no	15.279	14.773	EPSD	CCLE	13.873	Down-regulation
TKL_STKR_STKR1_TGFBR1_ST	P17813	ENG	P36897	TGFBR1	S619	T617M	617	Missense	proximal	-2	no	15.554	15.551	EPSD	CCLE	13.873	Down-regulation
CAMK_MAPKAPK_MK5_MAPKAPK5_ST	P25685	DNAJB1	Q8IW41	MAPKAPK5	S16	E18D	18	Missense	proximal	2	no	31.100	28.933	EPSD	CCLE	23.028	Down-regulation
CAMK_MAPKAPK_MK5_MAPKAPK5_ST	P25685	DNAJB1	Q8IW41	MAPKAPK5	S16	R13C	13	Missense	distal	-3	no	31.100	18.950	EPSD	CCLE	23.028	Loss
CAMK_MAPKAPK_MK5_MAPKAPK5_ST	P25685	DNAJB1	Q8IW41	MAPKAPK5	S196	K195N	195	Missense	proximal	-1	no	25.589	23.771	EPSD	CCLE	23.028	Down-regulation
CAMK_MAPKAPK_MK5_MAPKAPK5_ST	P07101	TH	Q8IW41	MAPKAPK5	S71	R68H	68	Missense	distal	-3	no	38.327	31.298	EPSD	CCLE	23.028	Down-regulation
CAMK_MAPKAPK_MK5_MAPKAPK5_ST	P07101	TH	Q8IW41	MAPKAPK5	S71	R68C	68	Missense	distal	-3	no	38.327	26.177	EPSD	CCLE	23.028	Down-regulation
CAMK_MAPKAPK_MK5_MAPKAPK5_ST	P07101	TH	Q8IW41	MAPKAPK5	S435	P438L	438	Missense	distal	3	no	41.810	42.048	EPSD	CCLE	23.028	Up-regulation
CAMK_DAPK_DAPK_DAPK2_ST	Q8N122	RPTOR	Q9UIK4	DAPK2	S721	R727G	727	Missense	distal	6	no	2.232	2.334	PhosphoSitePlus	CCLE	1.958	Up-regulation
CAMK_DAPK_DAPK_DAPK2_ST	Q8N122	RPTOR	Q9UIK4	DAPK2	T731	R727G	727	Missense	distal	-4	no	2.877	2.300	EPSD	CCLE	1.958	Down-regulation
AGC_PKC_PKCh_PRKCH_ST	P05107	ITGB2	P24723	PRKCH	T118	V117M	117	Missense	proximal	-1	no	24.636	25.273	EPSD	CCLE	22.099	Up-regulation
AGC_PKC_PKCh_PRKCH_ST	P24723	PRKCH	P24723	PRKCH	S28	S32W	32	Missense	distal	4	no	40.511	34.456	PhosphoSitePlus;EPSD	CCLE	22.099	Down-regulation
AGC_PKC_PKCh_PRKCH_ST	P24723	PRKCH	P24723	PRKCH	S32	S32W	32	Missense	central	0	yes	42.756	0.000	EPSD;PhosphoSitePlus	CCLE	22.099	Loss
AGC_PKC_PKCh_PRKCH_ST	P24723	PRKCH	P24723	PRKCH	S32	G37D	37	Missense	distal	5	no	42.756	43.291	EPSD;PhosphoSitePlus	CCLE	22.099	Up-regulation
AGC_PKC_PKCh_PRKCH_ST	Q15139	PRKD1	P24723	PRKCH	T422	M424V	424	Missense	proximal	2	no	23.621	24.387	EPSD	CCLE	22.099	Up-regulation
AGC_PKC_PKCh_PRKCH_ST	Q9BZL6	PRKD2	P24723	PRKCH	T266	S271G	271	Missense	distal	5	no	21.884	23.666	EPSD	CCLE	22.099	Gain
AGC_PKC_PKCh_PRKCH_ST	Q9BZL6	PRKD2	P24723	PRKCH	T276	K282R	282	Missense	distal	6	no	22.532	21.927	EPSD	CCLE	22.099	Loss
AGC_PKC_PKCh_PRKCH_ST	Q9BZL6	PRKD2	P24723	PRKCH	T276	S271G	271	Missense	distal	-5	no	22.532	22.028	EPSD	CCLE	22.099	Loss
AGC_PKC_PKCh_PRKCH_ST	P49840	GSK3A	P24723	PRKCH	S52	T46S	46	Missense	distal	-6	no	25.404	22.786	EPSD	CCLE	22.099	Down-regulation
AGC_PKC_PKCh_PRKCH_ST	P49840	GSK3A	P24723	PRKCH	S401	L395Q	395	Missense	distal	-6	no	24.798	24.711	EPSD	CCLE	22.099	Down-regulation
Other_PLK_PLK1_PLK1_ST	Q14203	DCTN1	P53350	PLK1	S974	V971M	971	Missense	distal	-3	no	12.138	12.266	EPSD	CCLE	10.919	Up-regulation
Other_PLK_PLK1_PLK1_ST	O60563	CCNT1	P53350	PLK1	T278	L284R	284	Missense	distal	6	no	11.485	11.139	EPSD	CCLE	10.919	Down-regulation
Other_PLK_PLK1_PLK1_ST	O60563	CCNT1	P53350	PLK1	T282	L284R	284	Missense	proximal	2	no	11.337	10.538	EPSD	CCLE	10.919	Loss
Other_PLK_PLK1_PLK1_ST	O60563	CCNT1	P53350	PLK1	S499	D498N	498	Missense	proximal	-1	no	12.128	11.195	EPSD	CCLE	10.919	Down-regulation
Other_PLK_PLK1_PLK1_ST	O60563	CCNT1	P53350	PLK1	S549	S549G	549	Missense	central	0	yes	11.229	0.000	EPSD	CCLE	10.919	Loss
Other_PLK_PLK1_PLK1_ST	O60563	CCNT1	P53350	PLK1	S577	V584M	584	Missense	distal	7	no	11.112	11.132	EPSD	CCLE	10.919	Up-regulation
Other_PLK_PLK1_PLK1_ST	O60563	CCNT1	P53350	PLK1	T580	V584M	584	Missense	distal	4	no	11.250	10.763	EPSD	CCLE	10.919	Loss
Other_PLK_PLK1_PLK1_ST	Q9Y2I6	NINL	P53350	PLK1	T1094	T1094A	1094	Missense	central	0	yes	11.828	0.000	EPSD	CCLE	10.919	Loss
Other_PLK_PLK1_PLK1_ST	Q9Y2I6	NINL	P53350	PLK1	S1267	H1263R	1263	Missense	distal	-4	no	13.812	13.511	EPSD	CCLE	10.919	Down-regulation
Other_PLK_PLK1_PLK1_ST	Q9Y2I6	NINL	P53350	PLK1	S1373	R1374G	1374	Missense	proximal	1	no	8.846	10.947	EPSD	CCLE	10.919	Gain
Other_PLK_PLK1_PLK1_ST	P30305	CDC25B	P53350	PLK1	S15	A13D	13	Missense	proximal	-2	no	8.754	11.326	EPSD	CCLE	10.919	Gain
Other_PLK_PLK1_PLK1_ST	P30305	CDC25B	P53350	PLK1	S50	V44G	44	Missense	distal	-6	no	13.331	13.060	EPSD;PhosphoSitePlus	CCLE	10.919	Down-regulation
Other_PLK_PLK1_PLK1_ST	P30305	CDC25B	P53350	PLK1	S50	R45Q	45	Missense	distal	-5	no	13.331	12.592	EPSD;PhosphoSitePlus	CCLE	10.919	Down-regulation
Other_PLK_PLK1_PLK1_ST	P30305	CDC25B	P53350	PLK1	T58	M59I	59	Missense	proximal	1	no	12.465	11.500	EPSD;PhosphoSitePlus	CCLE	10.919	Down-regulation
Other_PLK_PLK1_PLK1_ST	P33981	TTK	P53350	PLK1	S49	T45N	45	Missense	distal	-4	no	11.653	11.880	EPSD	CCLE	10.919	Up-regulation
Other_PLK_PLK1_PLK1_ST	P33981	TTK	P53350	PLK1	S291	K287N	287	Missense	distal	-4	no	14.312	14.570	EPSD;PhosphoSitePlus	CCLE	10.919	Up-regulation
Other_PLK_PLK1_PLK1_ST	Q96BK5	PINX1	P53350	PLK1	S226	P230L	230	Missense	distal	4	no	11.711	11.421	PhosphoSitePlus;EPSD	CCLE	10.919	Down-regulation
Other_PLK_PLK1_PLK1_ST	Q9H1A4	ANAPC1	P53350	PLK1	S351	R352H	352	Missense	proximal	1	no	10.172	11.569	EPSD	CCLE	10.919	Gain
Other_PLK_PLK1_PLK1_ST	Q9H1A4	ANAPC1	P53350	PLK1	S355	R352H	352	Missense	distal	-3	no	12.258	11.586	EPSD;PhosphoSitePlus	CCLE	10.919	Down-regulation
Other_PLK_PLK1_PLK1_ST	Q9H1A4	ANAPC1	P53350	PLK1	S377	I383L	383	Missense	distal	6	no	13.023	13.061	EPSD;PhosphoSitePlus	CCLE	10.919	Up-regulation
Other_PLK_PLK1_PLK1_ST	Q9H1A4	ANAPC1	P53350	PLK1	S386	I383L	383	Missense	distal	-3	no	11.140	11.515	EPSD	CCLE	10.919	Up-regulation
Other_PLK_PLK1_PLK1_ST	Q9H1A4	ANAPC1	P53350	PLK1	S564	L566H	566	Missense	proximal	2	no	12.442	12.345	EPSD	CCLE	10.919	Down-regulation
Other_PLK_PLK1_PLK1_ST	Q9H1A4	ANAPC1	P53350	PLK1	S1317	N1312I	1312	Missense	distal	-5	no	11.022	11.443	EPSD	CCLE	10.919	Up-regulation
Other_PLK_PLK1_PLK1_ST	Q99661	KIF2C	P53350	PLK1	S589	S592N	592	Missense	distal	3	no	14.763	14.808	EPSD	CCLE	10.919	Up-regulation
Other_PLK_PLK1_PLK1_ST	P35568	IRS1	P53350	PLK1	S272	S273L	273	Missense	proximal	1	no	9.014	10.982	EPSD	CCLE	10.919	Gain
Other_PLK_PLK1_PLK1_ST	P35568	IRS1	P53350	PLK1	S315	A314D	314	Missense	proximal	-1	no	10.551	11.811	EPSD	CCLE	10.919	Gain
Other_PLK_PLK1_PLK1_ST	P35568	IRS1	P53350	PLK1	S372	S374Y	374	Missense	proximal	2	no	14.136	13.768	EPSD	CCLE	10.919	Down-regulation
Other_PLK_PLK1_PLK1_ST	P35568	IRS1	P53350	PLK1	S398	T403P	403	Missense	distal	5	no	11.301	12.293	EPSD	CCLE	10.919	Up-regulation
Other_PLK_PLK1_PLK1_ST	P35568	IRS1	P53350	PLK1	S741	S747A	747	Missense	distal	6	no	11.207	11.490	EPSD	CCLE	10.919	Up-regulation
Other_PLK_PLK1_PLK1_ST	P35568	IRS1	P53350	PLK1	S741	V738M	738	Missense	distal	-3	no	11.207	11.335	EPSD	CCLE	10.919	Up-regulation
Other_PLK_PLK1_PLK1_ST	P35568	IRS1	P53350	PLK1	S1038	A1032T	1032	Missense	distal	-6	no	10.994	10.927	EPSD	CCLE	10.919	Down-regulation
Other_PLK_PLK1_PLK1_ST	P35568	IRS1	P53350	PLK1	S1038	M1031T	1031	Missense	distal	-7	no	10.994	11.415	EPSD	CCLE	10.919	Up-regulation
Other_PLK_PLK1_PLK1_ST	P35568	IRS1	P53350	PLK1	S1132	E1136K	1136	Missense	distal	4	no	11.149	10.775	EPSD	CCLE	10.919	Loss
Other_PLK_PLK1_PLK1_ST	Q49MG5	MAP9	P53350	PLK1	S255	E261K	261	Missense	distal	6	no	11.924	11.855	EPSD	CCLE	10.919	Down-regulation
Other_PLK_PLK1_PLK1_ST	Q49MG5	MAP9	P53350	PLK1	S255	F256I	256	Missense	proximal	1	no	11.924	10.635	EPSD	CCLE	10.919	Loss
Other_PLK_PLK1_PLK1_ST	Q49MG5	MAP9	P53350	PLK1	S336	T343A	343	Missense	distal	7	no	11.933	11.973	EPSD	CCLE	10.919	Up-regulation
Other_PLK_PLK1_PLK1_ST	Q49MG5	MAP9	P53350	PLK1	S338	T343A	343	Missense	distal	5	no	10.115	11.287	EPSD	CCLE	10.919	Gain
Other_PLK_PLK1_PLK1_ST	O95613	PCNT	P53350	PLK1	S49	K42E	42	Missense	distal	-7	no	13.249	13.553	EPSD	CCLE	10.919	Up-regulation
Other_PLK_PLK1_PLK1_ST	O95613	PCNT	P53350	PLK1	T539	Q535R	535	Missense	distal	-4	no	13.475	13.187	EPSD	CCLE	10.919	Down-regulation
Other_PLK_PLK1_PLK1_ST	O95613	PCNT	P53350	PLK1	S1006	K1004N	1004	Missense	proximal	-2	no	13.306	15.335	EPSD	CCLE	10.919	Up-regulation
Other_PLK_PLK1_PLK1_ST	O95613	PCNT	P53350	PLK1	T1209	T1209M	1209	Missense	central	0	yes	12.997	0.000	EPSD;PhosphoSitePlus	CCLE	10.919	Loss
Other_PLK_PLK1_PLK1_ST	O95613	PCNT	P53350	PLK1	S2433	S2433L	2433	Missense	central	0	yes	11.190	0.000	EPSD	CCLE	10.919	Loss
Other_PLK_PLK1_PLK1_ST	P30307	CDC25C	P53350	PLK1	S451	G456R	456	Missense	distal	5	no	11.295	11.457	EPSD	CCLE	10.919	Up-regulation
Other_PLK_PLK1_PLK1_ST	O43663	PRC1	P53350	PLK1	S587	A583S	583	Missense	distal	-4	no	14.025	13.986	EPSD	CCLE	10.919	Down-regulation
Other_PLK_PLK1_PLK1_ST	Q7L2Z9	CENPQ	P53350	PLK1	T169	T173I	173	Missense	distal	4	no	10.970	9.971	EPSD	CCLE	10.919	Loss
Other_PLK_PLK1_PLK1_ST	Q7L2Z9	CENPQ	P53350	PLK1	T173	T173I	173	Missense	central	0	yes	12.399	0.000	EPSD	CCLE	10.919	Loss
Other_PLK_PLK1_PLK1_ST	Q7L2Z9	CENPQ	P53350	PLK1	S253	E260D	260	Missense	distal	7	no	12.568	12.564	EPSD;PhosphoSitePlus	CCLE	10.919	Down-regulation
Other_PLK_PLK1_PLK1_ST	Q7L2Z9	CENPQ	P53350	PLK1	S255	E260D	260	Missense	distal	5	no	11.102	11.543	PhosphoSitePlus;EPSD	CCLE	10.919	Up-regulation
Other_PLK_PLK1_PLK1_ST	Q7L2Z9	CENPQ	P53350	PLK1	T256	E260D	260	Missense	distal	4	no	14.680	14.695	EPSD;PhosphoSitePlus	CCLE	10.919	Up-regulation
Other_PLK_PLK1_PLK1_ST	Q8IZD2	KMT2E	P53350	PLK1	T553	I549M	549	Missense	distal	-4	no	11.458	11.148	EPSD	CCLE	10.919	Down-regulation
Other_PLK_PLK1_PLK1_ST	Q8IZD2	KMT2E	P53350	PLK1	T553	K552R	552	Missense	proximal	-1	no	11.458	11.097	EPSD	CCLE	10.919	Down-regulation
Other_PLK_PLK1_PLK1_ST	Q8IZD2	KMT2E	P53350	PLK1	S780	Y779H	779	Missense	proximal	-1	no	11.472	11.197	EPSD	CCLE	10.919	Down-regulation
Other_PLK_PLK1_PLK1_ST	Q8IZD2	KMT2E	P53350	PLK1	S829	I831S	831	Missense	proximal	2	no	11.883	11.461	EPSD	CCLE	10.919	Down-regulation
Other_PLK_PLK1_PLK1_ST	Q9Y6D9	MAD1L1	P53350	PLK1	S420	L415V	415	Missense	distal	-5	no	13.823	13.370	EPSD	CCLE	10.919	Down-regulation
Other_PLK_PLK1_PLK1_ST	Q99708	RBBP8	P53350	PLK1	S231	A236S	236	Missense	distal	5	no	12.346	11.780	EPSD	CCLE	10.919	Down-regulation
Other_PLK_PLK1_PLK1_ST	Q99708	RBBP8	P53350	PLK1	S345	Q352P	352	Missense	distal	7	no	12.648	12.644	EPSD	CCLE	10.919	Down-regulation
Other_PLK_PLK1_PLK1_ST	Q99708	RBBP8	P53350	PLK1	S349	Q352P	352	Missense	distal	3	no	11.566	11.516	EPSD	CCLE	10.919	Down-regulation
Other_PLK_PLK1_PLK1_ST	Q99708	RBBP8	P53350	PLK1	S649	N652I	652	Missense	distal	3	no	11.567	11.551	EPSD	CCLE	10.919	Down-regulation
Other_PLK_PLK1_PLK1_ST	Q15022	SUZ12	P53350	PLK1	S384	P391S	391	Missense	distal	7	no	12.886	12.859	EPSD	CCLE	10.919	Down-regulation
Other_PLK_PLK1_PLK1_ST	Q15022	SUZ12	P53350	PLK1	S462	C457G	457	Missense	distal	-5	no	11.249	11.630	EPSD	CCLE	10.919	Up-regulation
Other_PLK_PLK1_PLK1_ST	Q15022	SUZ12	P53350	PLK1	S604	E610V	610	Missense	distal	6	no	11.616	11.602	EPSD	CCLE	10.919	Down-regulation
Other_PLK_PLK1_PLK1_ST	Q15022	SUZ12	P53350	PLK1	S726	E723K	723	Missense	distal	-3	no	13.282	13.823	EPSD	CCLE	10.919	Up-regulation
Other_PLK_PLK1_PLK1_ST	Q14676	MDC1	P53350	PLK1	S394	M398V	398	Missense	distal	4	no	13.136	13.623	EPSD	CCLE	10.919	Up-regulation
Other_PLK_PLK1_PLK1_ST	Q14676	MDC1	P53350	PLK1	S402	M398V	398	Missense	distal	-4	no	10.774	10.950	EPSD	CCLE	10.919	Gain
Other_PLK_PLK1_PLK1_ST	Q14676	MDC1	P53350	PLK1	S485	R478S	478	Missense	distal	-7	no	10.999	11.496	EPSD	CCLE	10.919	Up-regulation
Other_PLK_PLK1_PLK1_ST	Q14676	MDC1	P53350	PLK1	T847	Q843R	843	Missense	distal	-4	no	11.387	11.099	EPSD;PhosphoSitePlus	CCLE	10.919	Down-regulation
Other_PLK_PLK1_PLK1_ST	Q14676	MDC1	P53350	PLK1	T847	E841K	841	Missense	distal	-6	no	11.387	10.813	EPSD;PhosphoSitePlus	CCLE	10.919	Loss
Other_PLK_PLK1_PLK1_ST	Q14676	MDC1	P53350	PLK1	S1154	S1148N	1148	Missense	distal	-6	no	12.355	12.159	EPSD	CCLE	10.919	Down-regulation
Other_PLK_PLK1_PLK1_ST	Q14676	MDC1	P53350	PLK1	T1377	S1378F	1378	Missense	proximal	1	no	7.947	10.995	EPSD	CCLE	10.919	Gain
Other_PLK_PLK1_PLK1_ST	Q14676	MDC1	P53350	PLK1	T1406	V1408L	1408	Missense	proximal	2	no	11.265	11.133	EPSD	CCLE	10.919	Down-regulation
Other_PLK_PLK1_PLK1_ST	Q14676	MDC1	P53350	PLK1	S1563	R1557K	1557	Missense	distal	-6	no	10.963	10.956	EPSD	CCLE	10.919	Down-regulation
Other_PLK_PLK1_PLK1_ST	Q14676	MDC1	P53350	PLK1	S1564	R1557K	1557	Missense	distal	-7	no	11.022	11.154	EPSD	CCLE	10.919	Up-regulation
Other_PLK_PLK1_PLK1_ST	Q14676	MDC1	P53350	PLK1	S1924	R1930H	1930	Missense	distal	6	no	12.058	11.842	EPSD	CCLE	10.919	Down-regulation
Other_PLK_PLK1_PLK1_ST	O00139	KIF2A	P53350	PLK1	S516	R514K	514	Missense	proximal	-2	no	14.156	13.763	EPSD	CCLE	10.919	Down-regulation
Other_PLK_PLK1_PLK1_ST	P30260	CDC27	P53350	PLK1	T200	E199Q	199	Missense	proximal	-1	no	10.943	10.614	EPSD	CCLE	10.919	Loss
Other_PLK_PLK1_PLK1_ST	P30260	CDC27	P53350	PLK1	T205	E199Q	199	Missense	distal	-6	no	12.506	12.387	EPSD;PhosphoSitePlus	CCLE	10.919	Down-regulation
Other_PLK_PLK1_PLK1_ST	P30260	CDC27	P53350	PLK1	T327	G325D	325	Missense	proximal	-2	no	8.951	12.273	EPSD	CCLE	10.919	Gain
Other_PLK_PLK1_PLK1_ST	Q96CV9	OPTN	P53350	PLK1	T20	E13D	13	Missense	distal	-7	no	13.940	13.651	EPSD	CCLE	10.919	Down-regulation
Other_PLK_PLK1_PLK1_ST	Q96CV9	OPTN	P53350	PLK1	T20	L27V	27	Missense	distal	7	no	13.940	13.990	EPSD	CCLE	10.919	Up-regulation
Other_PLK_PLK1_PLK1_ST	Q96CV9	OPTN	P53350	PLK1	S216	R217I	217	Missense	proximal	1	no	9.997	12.920	EPSD	CCLE	10.919	Gain
Other_PLK_PLK1_PLK1_ST	Q96CV9	OPTN	P53350	PLK1	S528	T525A	525	Missense	distal	-3	no	12.087	12.233	EPSD	CCLE	10.919	Up-regulation
Other_PLK_PLK1_PLK1_ST	Q96CV9	OPTN	P53350	PLK1	S528	Q530K	530	Missense	proximal	2	no	12.087	11.729	EPSD	CCLE	10.919	Down-regulation
Other_PLK_PLK1_PLK1_ST	Q9HAW4	CLSPN	P53350	PLK1	S113	K117R	117	Missense	distal	4	no	13.398	12.838	EPSD	CCLE	10.919	Down-regulation
Other_PLK_PLK1_PLK1_ST	Q9HAW4	CLSPN	P53350	PLK1	S839	Y843S	843	Missense	distal	4	no	12.769	13.012	EPSD	CCLE	10.919	Up-regulation
Other_PLK_PLK1_PLK1_ST	Q9HAW4	CLSPN	P53350	PLK1	S969	G971S	971	Missense	proximal	2	no	13.432	15.013	EPSD	CCLE	10.919	Up-regulation
Other_PLK_PLK1_PLK1_ST	Q9HAW4	CLSPN	P53350	PLK1	S1147	M1149T	1149	Missense	proximal	2	no	11.081	10.443	EPSD	CCLE	10.919	Loss
Other_PLK_PLK1_PLK1_ST	Q13526	PIN1	P53350	PLK1	S147	V150M	150	Missense	distal	3	no	11.576	11.135	EPSD	CCLE	10.919	Down-regulation
Other_PLK_PLK1_PLK1_ST	Q14674	ESPL1	P53350	PLK1	S325	P329T	329	Missense	distal	4	no	13.012	13.141	EPSD	CCLE	10.919	Up-regulation
Other_PLK_PLK1_PLK1_ST	Q14674	ESPL1	P53350	PLK1	T1111	G1117D	1117	Missense	distal	6	no	11.985	12.460	EPSD	CCLE	10.919	Up-regulation
Other_PLK_PLK1_PLK1_ST	Q14674	ESPL1	P53350	PLK1	S1122	G1117D	1117	Missense	distal	-5	no	10.922	10.767	EPSD	CCLE	10.919	Loss
Other_PLK_PLK1_PLK1_ST	Q14674	ESPL1	P53350	PLK1	S1126	K1130E	1130	Missense	distal	4	no	12.281	12.655	EPSD	CCLE	10.919	Up-regulation
Other_PLK_PLK1_PLK1_ST	P47736	RAP1GAP	P53350	PLK1	S460	T454I	454	Missense	distal	-6	no	10.797	10.969	EPSD	CCLE	10.919	Gain
Other_PLK_PLK1_PLK1_ST	O75170	PPP6R2	P53350	PLK1	S289	L294Q	294	Missense	distal	5	no	12.308	12.203	EPSD;PhosphoSitePlus	CCLE	10.919	Down-regulation
Other_PLK_PLK1_PLK1_ST	O75170	PPP6R2	P53350	PLK1	S297	L294Q	294	Missense	distal	-3	no	11.628	11.011	EPSD	CCLE	10.919	Down-regulation
Other_PLK_PLK1_PLK1_ST	O75170	PPP6R2	P53350	PLK1	S822	A819V	819	Missense	distal	-3	no	11.006	10.607	EPSD	CCLE	10.919	Loss
Other_PLK_PLK1_PLK1_ST	O75170	PPP6R2	P53350	PLK1	S823	A819V	819	Missense	distal	-4	no	11.551	11.411	EPSD	CCLE	10.919	Down-regulation
Other_PLK_PLK1_PLK1_ST	O14920	IKBKB	P53350	PLK1	S733	E729Q	729	Missense	distal	-4	no	16.117	15.849	EPSD;PhosphoSitePlus	CCLE	10.919	Down-regulation
Other_PLK_PLK1_PLK1_ST	P11388	TOP2A	P53350	PLK1	S312	S316N	316	Missense	distal	4	no	14.228	13.992	EPSD	CCLE	10.919	Down-regulation
Other_PLK_PLK1_PLK1_ST	P11388	TOP2A	P53350	PLK1	T808	R815Q	815	Missense	distal	7	no	11.534	11.549	EPSD	CCLE	10.919	Up-regulation
Other_PLK_PLK1_PLK1_ST	P11388	TOP2A	P53350	PLK1	S1476	I1481N	1481	Missense	distal	5	no	11.082	10.181	EPSD	CCLE	10.919	Loss
Other_PLK_PLK1_PLK1_ST	Q8NHV4	NEDD1	P53350	PLK1	S637	E634K	634	Missense	distal	-3	no	12.013	12.553	PhosphoSitePlus;EPSD	CCLE	10.919	Up-regulation
Other_PLK_PLK1_PLK1_ST	Q8NHV4	NEDD1	P53350	PLK1	S637	G641V	641	Missense	distal	4	no	12.013	11.636	PhosphoSitePlus;EPSD	CCLE	10.919	Down-regulation
Other_PLK_PLK1_PLK1_ST	P18031	PTPN1	P53350	PLK1	S50	P51S	51	Missense	proximal	1	no	15.413	14.291	EPSD	CCLE	10.919	Down-regulation
Other_PLK_PLK1_PLK1_ST	Q8N4N8	KIF2B	P53350	PLK1	T457	A455E	455	Missense	proximal	-2	no	9.703	11.881	EPSD	CCLE	10.919	Gain
Other_PLK_PLK1_PLK1_ST	Q8N4N8	KIF2B	P53350	PLK1	S474	L478P	478	Missense	distal	4	no	12.257	12.547	EPSD	CCLE	10.919	Up-regulation
Other_PLK_PLK1_PLK1_ST	P0DMV8	HSPA1A	P53350	PLK1	S544	A538T	538	Missense	distal	-6	no	11.463	11.396	EPSD	CCLE	10.919	Down-regulation
Other_PLK_PLK1_PLK1_ST	O14641	DVL2	P53350	PLK1	S170	E171K	171	Missense	proximal	1	no	13.804	13.354	EPSD	CCLE	10.919	Down-regulation
Other_PLK_PLK1_PLK1_ST	Q3KR16	PLEKHG6	P53350	PLK1	S204	G198E	198	Missense	distal	-6	no	10.444	11.109	EPSD	CCLE	10.919	Gain
Other_PLK_PLK1_PLK1_ST	Q3KR16	PLEKHG6	P53350	PLK1	S712	P708S	708	Missense	distal	-4	no	12.486	12.608	EPSD	CCLE	10.919	Up-regulation
Other_PLK_PLK1_PLK1_ST	Q9H2D6	TRIOBP	P53350	PLK1	S294	E298A	298	Missense	distal	4	no	11.684	11.496	EPSD	CCLE	10.919	Down-regulation
Other_PLK_PLK1_PLK1_ST	Q9H2D6	TRIOBP	P53350	PLK1	S294	E298V	298	Missense	distal	4	no	11.684	11.233	EPSD	CCLE	10.919	Down-regulation
Other_PLK_PLK1_PLK1_ST	Q9H2D6	TRIOBP	P53350	PLK1	S300	E298A	298	Missense	proximal	-2	no	11.192	9.014	EPSD	CCLE	10.919	Loss
Other_PLK_PLK1_PLK1_ST	Q9H2D6	TRIOBP	P53350	PLK1	S300	E298V	298	Missense	proximal	-2	no	11.192	8.974	EPSD	CCLE	10.919	Loss
Other_PLK_PLK1_PLK1_ST	Q9H2D6	TRIOBP	P53350	PLK1	S304	E298A	298	Missense	distal	-6	no	12.189	12.034	EPSD	CCLE	10.919	Down-regulation
Other_PLK_PLK1_PLK1_ST	Q9H2D6	TRIOBP	P53350	PLK1	S304	E298V	298	Missense	distal	-6	no	12.189	11.795	EPSD	CCLE	10.919	Down-regulation
Other_PLK_PLK1_PLK1_ST	Q9H2D6	TRIOBP	P53350	PLK1	S1133	P1140H	1140	Missense	distal	7	no	11.981	11.940	EPSD	CCLE	10.919	Down-regulation
Other_PLK_PLK1_PLK1_ST	Q9H2D6	TRIOBP	P53350	PLK1	S1900	E1903D	1903	Missense	distal	3	no	12.527	12.593	EPSD	CCLE	10.919	Up-regulation
Other_PLK_PLK1_PLK1_ST	Q9H2D6	TRIOBP	P53350	PLK1	S2329	E2336Q	2336	Missense	distal	7	no	12.366	12.419	EPSD	CCLE	10.919	Up-regulation
Other_PLK_PLK1_PLK1_ST	Q00839	HNRNPU	P53350	PLK1	T474	P470H	470	Missense	distal	-4	no	13.648	13.505	EPSD	CCLE	10.919	Down-regulation
Other_PLK_PLK1_PLK1_ST	O94901	SUN1	P53350	PLK1	T199	T199M	199	Missense	central	0	yes	11.150	0.000	EPSD	CCLE	10.919	Loss
Other_PLK_PLK1_PLK1_ST	Q13158	FADD	P53350	PLK1	S190	M193T	193	Missense	distal	3	no	11.755	11.908	EPSD	CCLE	10.919	Up-regulation
Other_PLK_PLK1_PLK1_ST	Q13158	FADD	P53350	PLK1	S194	M193T	193	Missense	proximal	-1	no	13.059	12.240	PhosphoSitePlus	CCLE	10.919	Down-regulation
Other_PLK_PLK1_PLK1_ST	Q13158	FADD	P53350	PLK1	S197	M193T	193	Missense	distal	-4	no	11.761	11.675	EPSD	CCLE	10.919	Down-regulation
Other_PLK_PLK1_PLK1_ST	P38398	BRCA1	P53350	PLK1	S316	R315M	315	Missense	proximal	-1	no	10.006	11.014	EPSD	CCLE	10.919	Gain
Other_PLK_PLK1_PLK1_ST	P38398	BRCA1	P53350	PLK1	S398	E404D	404	Missense	distal	6	no	13.579	13.728	EPSD	CCLE	10.919	Up-regulation
Other_PLK_PLK1_PLK1_ST	P38398	BRCA1	P53350	PLK1	S405	E404D	404	Missense	proximal	-1	no	10.794	11.590	EPSD	CCLE	10.919	Gain
Other_PLK_PLK1_PLK1_ST	P38398	BRCA1	P53350	PLK1	S844	E851G	851	Missense	distal	7	no	11.509	11.530	EPSD	CCLE	10.919	Up-regulation
Other_PLK_PLK1_PLK1_ST	P38398	BRCA1	P53350	PLK1	S988	F989L	989	Missense	proximal	1	no	11.154	10.073	EPSD	CCLE	10.919	Loss
Other_PLK_PLK1_PLK1_ST	P38398	BRCA1	P53350	PLK1	S1266	N1272D	1272	Missense	distal	6	no	12.154	12.374	EPSD	CCLE	10.919	Up-regulation
Other_PLK_PLK1_PLK1_ST	P38398	BRCA1	P53350	PLK1	S1266	C1270Y	1270	Missense	distal	4	no	12.154	12.438	EPSD	CCLE	10.919	Up-regulation
Other_PLK_PLK1_PLK1_ST	P38398	BRCA1	P53350	PLK1	S1271	C1270Y	1270	Missense	proximal	-1	no	9.732	11.928	EPSD	CCLE	10.919	Gain
Other_PLK_PLK1_PLK1_ST	P38398	BRCA1	P53350	PLK1	S1551	D1557N	1557	Missense	distal	6	no	12.480	12.260	EPSD	CCLE	10.919	Down-regulation
Other_PLK_PLK1_PLK1_ST	P38398	BRCA1	P53350	PLK1	T1561	D1557N	1557	Missense	distal	-4	no	10.899	10.958	EPSD	CCLE	10.919	Gain
Other_PLK_PLK1_PLK1_ST	P38398	BRCA1	P53350	PLK1	S1610	E1609D	1609	Missense	proximal	-1	no	11.176	11.972	EPSD	CCLE	10.919	Up-regulation
Other_PLK_PLK1_PLK1_ST	P51587	BRCA2	P53350	PLK1	S93	E97D	97	Missense	distal	4	no	14.668	14.683	EPSD	CCLE	10.919	Up-regulation
Other_PLK_PLK1_PLK1_ST	P51587	BRCA2	P53350	PLK1	T926	E919K	919	Missense	distal	-7	no	11.657	11.353	EPSD	CCLE	10.919	Down-regulation
Other_PLK_PLK1_PLK1_ST	P51587	BRCA2	P53350	PLK1	S1659	Y1655L	1655	Missense	distal	-4	no	10.488	10.982	EPSD	CCLE	10.919	Gain
Other_PLK_PLK1_PLK1_ST	P51587	BRCA2	P53350	PLK1	S1680	V1681M	1681	Missense	proximal	1	no	9.918	11.074	EPSD	CCLE	10.919	Gain
Other_PLK_PLK1_PLK1_ST	P51587	BRCA2	P53350	PLK1	S1869	D1864Y	1864	Missense	distal	-5	no	11.617	11.471	EPSD	CCLE	10.919	Down-regulation
Other_PLK_PLK1_PLK1_ST	P51587	BRCA2	P53350	PLK1	S1951	E1953D	1953	Missense	proximal	2	no	12.018	12.608	EPSD	CCLE	10.919	Up-regulation
Other_PLK_PLK1_PLK1_ST	P51587	BRCA2	P53350	PLK1	S1955	E1953D	1953	Missense	proximal	-2	no	12.341	12.734	EPSD	CCLE	10.919	Up-regulation
Other_PLK_PLK1_PLK1_ST	P51587	BRCA2	P53350	PLK1	S2701	S2705G	2705	Missense	distal	4	no	12.697	12.612	EPSD	CCLE	10.919	Down-regulation
Other_PLK_PLK1_PLK1_ST	Q38SD2	LRRK1	P53350	PLK1	S1302	N1300S	1300	Missense	proximal	-2	no	11.509	10.099	EPSD	CCLE	10.919	Loss
Other_PLK_PLK1_PLK1_ST	Q9UBB4	ATXN10	P53350	PLK1	T426	Y420C	420	Missense	distal	-6	no	11.561	11.211	EPSD	CCLE	10.919	Down-regulation
Other_PLK_PLK1_PLK1_ST	Q9H0H5	RACGAP1	P53350	PLK1	S66	A61T	61	Missense	distal	-5	no	12.638	12.569	EPSD	CCLE	10.919	Down-regulation
Other_PLK_PLK1_PLK1_ST	Q9H0H5	RACGAP1	P53350	PLK1	S149	I152L	152	Missense	distal	3	no	12.161	11.986	EPSD	CCLE	10.919	Down-regulation
Other_PLK_PLK1_PLK1_ST	Q9H0H5	RACGAP1	P53350	PLK1	S151	I152L	152	Missense	proximal	1	no	10.773	10.981	EPSD	CCLE	10.919	Gain
Other_PLK_PLK1_PLK1_ST	Q9H0H5	RACGAP1	P53350	PLK1	S157	D162E	162	Missense	distal	5	no	16.092	15.651	EPSD;PhosphoSitePlus	CCLE	10.919	Down-regulation
Other_PLK_PLK1_PLK1_ST	Q9H0H5	RACGAP1	P53350	PLK1	S157	I152L	152	Missense	distal	-5	no	16.092	16.387	EPSD;PhosphoSitePlus	CCLE	10.919	Up-regulation
Other_PLK_PLK1_PLK1_ST	Q9H0H5	RACGAP1	P53350	PLK1	S164	D162E	162	Missense	proximal	-2	no	15.296	14.902	EPSD;PhosphoSitePlus	CCLE	10.919	Down-regulation
Other_PLK_PLK1_PLK1_ST	Q9H0H5	RACGAP1	P53350	PLK1	S259	L261P	261	Missense	proximal	2	no	12.148	10.600	EPSD	CCLE	10.919	Loss
Other_PLK_PLK1_PLK1_ST	Q9H0H5	RACGAP1	P53350	PLK1	T260	L261P	261	Missense	proximal	1	no	13.596	12.750	EPSD;PhosphoSitePlus	CCLE	10.919	Down-regulation
Other_PLK_PLK1_PLK1_ST	Q9H0H5	RACGAP1	P53350	PLK1	S593	R599H	599	Missense	distal	6	no	11.836	11.620	EPSD	CCLE	10.919	Down-regulation
Other_PLK_PLK1_PLK1_ST	Q9H0H5	RACGAP1	P53350	PLK1	S593	P589T	589	Missense	distal	-4	no	11.836	11.595	EPSD	CCLE	10.919	Down-regulation
Other_PLK_PLK1_PLK1_ST	Q9H0H5	RACGAP1	P53350	PLK1	T606	P607S	607	Missense	proximal	1	no	11.098	9.976	EPSD	CCLE	10.919	Loss
Other_PLK_PLK1_PLK1_ST	Q9H0H5	RACGAP1	P53350	PLK1	T606	R599H	599	Missense	distal	-7	no	11.098	11.478	EPSD	CCLE	10.919	Up-regulation
Other_PLK_PLK1_PLK1_ST	Q9H0H5	RACGAP1	P53350	PLK1	S613	S615P	615	Missense	proximal	2	no	11.889	10.413	EPSD	CCLE	10.919	Loss
Other_PLK_PLK1_PLK1_ST	Q9H0H5	RACGAP1	P53350	PLK1	S613	P607S	607	Missense	distal	-6	no	11.889	12.513	EPSD	CCLE	10.919	Up-regulation
Other_PLK_PLK1_PLK1_ST	O95251	KAT7	P53350	PLK1	S152	A154D	154	Missense	proximal	2	no	12.663	12.902	EPSD	CCLE	10.919	Up-regulation
Other_PLK_PLK1_PLK1_ST	O95251	KAT7	P53350	PLK1	S152	L159M	159	Missense	distal	7	no	12.663	12.733	EPSD	CCLE	10.919	Up-regulation
Other_PLK_PLK1_PLK1_ST	O95251	KAT7	P53350	PLK1	S158	A154D	154	Missense	distal	-4	no	17.801	17.567	EPSD	CCLE	10.919	Down-regulation
Other_PLK_PLK1_PLK1_ST	O95251	KAT7	P53350	PLK1	S158	L159M	159	Missense	proximal	1	no	17.801	18.557	EPSD	CCLE	10.919	Up-regulation
Other_PLK_PLK1_PLK1_ST	O95251	KAT7	P53350	PLK1	S405	R400S	400	Missense	distal	-5	no	11.138	10.455	EPSD	CCLE	10.919	Loss
Other_PLK_PLK1_PLK1_ST	Q13127	REST	P53350	PLK1	S96	A97V	97	Missense	proximal	1	no	11.172	12.610	EPSD	CCLE	10.919	Up-regulation
Other_PLK_PLK1_PLK1_ST	Q13127	REST	P53350	PLK1	S96	K100N	100	Missense	distal	4	no	11.172	11.321	EPSD	CCLE	10.919	Up-regulation
Other_PLK_PLK1_PLK1_ST	Q13127	REST	P53350	PLK1	S201	S203C	203	Missense	proximal	2	no	13.019	12.046	EPSD	CCLE	10.919	Down-regulation
Other_PLK_PLK1_PLK1_ST	Q13127	REST	P53350	PLK1	S204	S203C	203	Missense	proximal	-1	no	13.943	12.083	EPSD	CCLE	10.919	Down-regulation
Other_PLK_PLK1_PLK1_ST	Q13127	REST	P53350	PLK1	T442	I448T	448	Missense	distal	6	no	10.802	11.077	EPSD	CCLE	10.919	Gain
Other_PLK_PLK1_PLK1_ST	Q13127	REST	P53350	PLK1	S782	E780D	780	Missense	proximal	-2	no	11.384	11.778	EPSD	CCLE	10.919	Up-regulation
Other_PLK_PLK1_PLK1_ST	Q13127	REST	P53350	PLK1	S1024	D1018Y	1018	Missense	distal	-6	no	12.526	11.757	EPSD	CCLE	10.919	Down-regulation
Other_PLK_PLK1_PLK1_ST	Q13127	REST	P53350	PLK1	S1024	D1021V	1021	Missense	distal	-3	no	12.526	12.360	EPSD	CCLE	10.919	Down-regulation
Other_PLK_PLK1_PLK1_ST	P30622	CLIP1	P53350	PLK1	T302	T302P	302	Missense	central	0	yes	11.554	0.000	EPSD	CCLE	10.919	Loss
Other_PLK_PLK1_PLK1_ST	P30622	CLIP1	P53350	PLK1	T302	V296A	296	Missense	distal	-6	no	11.554	11.793	EPSD	CCLE	10.919	Up-regulation
Other_PLK_PLK1_PLK1_ST	P30622	CLIP1	P53350	PLK1	S306	T302P	302	Missense	distal	-4	no	11.868	12.108	EPSD	CCLE	10.919	Up-regulation
Other_PLK_PLK1_PLK1_ST	P30622	CLIP1	P53350	PLK1	S312	L316V	316	Missense	distal	4	no	11.365	11.515	EPSD;PhosphoSitePlus	CCLE	10.919	Up-regulation
Other_PLK_PLK1_PLK1_ST	P30622	CLIP1	P53350	PLK1	S318	L316V	316	Missense	proximal	-2	no	10.672	11.660	EPSD	CCLE	10.919	Gain
Other_PLK_PLK1_PLK1_ST	P30622	CLIP1	P53350	PLK1	T501	T505A	505	Missense	distal	4	no	11.595	11.588	EPSD	CCLE	10.919	Down-regulation
Other_PLK_PLK1_PLK1_ST	P30622	CLIP1	P53350	PLK1	T501	T501A	501	Missense	central	0	yes	11.595	0.000	EPSD	CCLE	10.919	Loss
Other_PLK_PLK1_PLK1_ST	P30622	CLIP1	P53350	PLK1	T505	T505A	505	Missense	central	0	yes	11.629	0.000	EPSD	CCLE	10.919	Loss
Other_PLK_PLK1_PLK1_ST	P30622	CLIP1	P53350	PLK1	T505	T501A	501	Missense	distal	-4	no	11.629	12.031	EPSD	CCLE	10.919	Up-regulation
Other_PLK_PLK1_PLK1_ST	P30622	CLIP1	P53350	PLK1	S1066	R1062Q	1062	Missense	distal	-4	no	11.272	11.560	EPSD	CCLE	10.919	Up-regulation
Other_PLK_PLK1_PLK1_ST	P30622	CLIP1	P53350	PLK1	T1112	K1118R	1118	Missense	distal	6	no	12.379	12.019	EPSD	CCLE	10.919	Down-regulation
Other_PLK_PLK1_PLK1_ST	Q76N32	CEP68	P53350	PLK1	S260	A259V	259	Missense	proximal	-1	no	12.703	12.213	EPSD	CCLE	10.919	Down-regulation
Other_PLK_PLK1_PLK1_ST	Q76N32	CEP68	P53350	PLK1	S374	P370S	370	Missense	distal	-4	no	13.003	13.124	EPSD	CCLE	10.919	Up-regulation
Other_PLK_PLK1_PLK1_ST	Q15468	STIL	P53350	PLK1	S1135	S1135N	1135	Missense	central	0	yes	12.034	0.000	EPSD	CCLE	10.919	Loss
Other_PLK_PLK1_PLK1_ST	Q9UJX5	ANAPC4	P53350	PLK1	S285	K289N	289	Missense	distal	4	no	11.078	11.227	EPSD	CCLE	10.919	Up-regulation
Other_PLK_PLK1_PLK1_ST	Q92574	TSC1	P53350	PLK1	T293	T294A	294	Missense	proximal	1	no	11.905	11.443	EPSD	CCLE	10.919	Down-regulation
Other_PLK_PLK1_PLK1_ST	Q92574	TSC1	P53350	PLK1	S472	E469G	469	Missense	distal	-3	no	15.054	15.995	EPSD	CCLE	10.919	Up-regulation
Other_PLK_PLK1_PLK1_ST	Q92574	TSC1	P53350	PLK1	S1071	P1075R	1075	Missense	distal	4	no	11.015	10.392	EPSD	CCLE	10.919	Loss
Other_PLK_PLK1_PLK1_ST	O60566	BUB1B	P53350	PLK1	S270	N268D	268	Missense	proximal	-2	no	11.658	12.900	EPSD	CCLE	10.919	Up-regulation
Other_PLK_PLK1_PLK1_ST	O60566	BUB1B	P53350	PLK1	S270	I272L	272	Missense	proximal	2	no	11.658	11.308	EPSD	CCLE	10.919	Down-regulation
Other_PLK_PLK1_PLK1_ST	O60566	BUB1B	P53350	PLK1	S574	N570H	570	Missense	distal	-4	no	11.781	11.651	EPSD	CCLE	10.919	Down-regulation
Other_PLK_PLK1_PLK1_ST	O60566	BUB1B	P53350	PLK1	T1008	D1005N	1005	Missense	distal	-3	no	11.310	11.210	PhosphoSitePlus;EPSD	CCLE	10.919	Down-regulation
Other_PLK_PLK1_PLK1_ST	Q14790	CASP8	P53350	PLK1	S16	E12Q	12	Missense	distal	-4	no	12.066	11.797	EPSD	CCLE	10.919	Down-regulation
Other_PLK_PLK1_PLK1_ST	Q14790	CASP8	P53350	PLK1	S305	M307V	307	Missense	proximal	2	no	12.108	12.314	PhosphoSitePlus	CCLE	10.919	Up-regulation
Other_PLK_PLK1_PLK1_ST	Q6IBW4	NCAPH2	P53350	PLK1	T50	T49A	49	Missense	proximal	-1	no	11.914	12.194	EPSD	CCLE	10.919	Up-regulation
Other_PLK_PLK1_PLK1_ST	Q6IBW4	NCAPH2	P53350	PLK1	S385	G383D	383	Missense	proximal	-2	no	7.826	11.148	EPSD	CCLE	10.919	Gain
Other_PLK_PLK1_PLK1_ST	Q9Y266	NUDC	P53350	PLK1	S231	S232L	232	Missense	proximal	1	no	11.497	13.464	EPSD	CCLE	10.919	Up-regulation
Other_PLK_PLK1_PLK1_ST	Q8TEP8	CEP192	P53350	PLK1	S313	N316S	316	Missense	distal	3	no	11.893	11.847	EPSD	CCLE	10.919	Down-regulation
Other_PLK_PLK1_PLK1_ST	Q8TEP8	CEP192	P53350	PLK1	S1871	K1878T	1878	Missense	distal	7	no	13.563	13.497	EPSD	CCLE	10.919	Down-regulation
Other_PLK_PLK1_PLK1_ST	Q99640	PKMYT1	P53350	PLK1	S469	L466P	466	Missense	distal	-3	no	13.246	12.054	EPSD	CCLE	10.919	Down-regulation
Other_PLK_PLK1_PLK1_ST	O60216	RAD21	P53350	PLK1	S134	F133L	133	Missense	proximal	-1	no	11.727	11.806	EPSD	CCLE	10.919	Up-regulation
Other_PLK_PLK1_PLK1_ST	O60216	RAD21	P53350	PLK1	S138	F133L	133	Missense	distal	-5	no	11.704	12.629	EPSD	CCLE	10.919	Up-regulation
Other_PLK_PLK1_PLK1_ST	O60216	RAD21	P53350	PLK1	T312	T312A	312	Missense	central	0	yes	11.659	0.000	EPSD	CCLE	10.919	Loss
Other_PLK_PLK1_PLK1_ST	O43379	WDR62	P53350	PLK1	S20	A14S	14	Missense	distal	-6	no	11.263	11.298	EPSD	CCLE	10.919	Up-regulation
Other_PLK_PLK1_PLK1_ST	O43379	WDR62	P53350	PLK1	S992	A997T	997	Missense	distal	5	no	11.431	10.259	EPSD	CCLE	10.919	Loss
Other_PLK_PLK1_PLK1_ST	O43379	WDR62	P53350	PLK1	S1002	A997T	997	Missense	distal	-5	no	11.666	11.598	EPSD	CCLE	10.919	Down-regulation
Other_PLK_PLK1_PLK1_ST	O43379	WDR62	P53350	PLK1	S1144	R1137T	1137	Missense	distal	-7	no	12.165	12.653	EPSD	CCLE	10.919	Up-regulation
Other_PLK_PLK1_PLK1_ST	O43379	WDR62	P53350	PLK1	T1159	L1160P	1160	Missense	proximal	1	no	14.045	13.199	EPSD	CCLE	10.919	Down-regulation
Other_PLK_PLK1_PLK1_ST	Q92994	BRF1	P53350	PLK1	T355	D354N	354	Missense	proximal	-1	no	14.256	13.323	EPSD	CCLE	10.919	Down-regulation
Other_PLK_PLK1_PLK1_ST	O96017	CHEK2	P53350	PLK1	S210	A215E	215	Missense	distal	5	no	13.565	12.707	EPSD;PhosphoSitePlus	CCLE	10.919	Down-regulation
Other_PLK_PLK1_PLK1_ST	O96017	CHEK2	P53350	PLK1	S357	D361G	361	Missense	distal	4	no	12.026	11.938	EPSD	CCLE	10.919	Down-regulation
Other_PLK_PLK1_PLK1_ST	O96017	CHEK2	P53350	PLK1	S505	L512I	512	Missense	distal	7	no	11.983	12.017	EPSD	CCLE	10.919	Up-regulation
Other_PLK_PLK1_PLK1_ST	O60285	NUAK1	P53350	PLK1	S455	M462I	462	Missense	distal	7	no	11.278	11.242	EPSD	CCLE	10.919	Down-regulation
Other_PLK_PLK1_PLK1_ST	O60285	NUAK1	P53350	PLK1	S550	E553Q	553	Missense	distal	3	no	15.347	15.239	EPSD	CCLE	10.919	Down-regulation
Other_PLK_PLK1_PLK1_ST	O60285	NUAK1	P53350	PLK1	S550	P546L	546	Missense	distal	-4	no	15.347	15.275	EPSD	CCLE	10.919	Down-regulation
Other_PLK_PLK1_PLK1_ST	Q12888	TP53BP1	P53350	PLK1	S25	E28A	28	Missense	distal	3	no	14.174	13.818	EPSD	CCLE	10.919	Down-regulation
Other_PLK_PLK1_PLK1_ST	Q12888	TP53BP1	P53350	PLK1	S395	K390R	390	Missense	distal	-5	no	13.544	14.082	EPSD	CCLE	10.919	Up-regulation
Other_PLK_PLK1_PLK1_ST	Q12888	TP53BP1	P53350	PLK1	S518	L517H	517	Missense	proximal	-1	no	10.584	11.104	EPSD	CCLE	10.919	Gain
Other_PLK_PLK1_PLK1_ST	Q12888	TP53BP1	P53350	PLK1	S523	L517H	517	Missense	distal	-6	no	12.026	12.372	EPSD	CCLE	10.919	Up-regulation
Other_PLK_PLK1_PLK1_ST	Q12888	TP53BP1	P53350	PLK1	S552	S557F	557	Missense	distal	5	no	12.408	12.502	EPSD	CCLE	10.919	Up-regulation
Other_PLK_PLK1_PLK1_ST	Q12888	TP53BP1	P53350	PLK1	S867	K873E	873	Missense	distal	6	no	11.417	11.486	EPSD	CCLE	10.919	Up-regulation
Other_PLK_PLK1_PLK1_ST	Q12888	TP53BP1	P53350	PLK1	S1002	T996A	996	Missense	distal	-6	no	13.048	13.115	EPSD	CCLE	10.919	Up-regulation
Other_PLK_PLK1_PLK1_ST	Q12888	TP53BP1	P53350	PLK1	S1002	E995Q	995	Missense	distal	-7	no	13.048	13.012	EPSD	CCLE	10.919	Down-regulation
Other_PLK_PLK1_PLK1_ST	Q12888	TP53BP1	P53350	PLK1	T1273	T1270I	1270	Missense	distal	-3	no	11.876	11.899	EPSD	CCLE	10.919	Up-regulation
Other_PLK_PLK1_PLK1_ST	Q12888	TP53BP1	P53350	PLK1	S1426	I1422T	1422	Missense	distal	-4	no	13.355	12.959	EPSD	CCLE	10.919	Down-regulation
Other_PLK_PLK1_PLK1_ST	Q12888	TP53BP1	P53350	PLK1	S1571	R1578T	1578	Missense	distal	7	no	13.488	13.458	EPSD	CCLE	10.919	Down-regulation
Other_PLK_PLK1_PLK1_ST	Q12888	TP53BP1	P53350	PLK1	S1631	V1633I	1633	Missense	proximal	2	no	11.235	11.452	EPSD	CCLE	10.919	Up-regulation
Other_PLK_PLK1_PLK1_ST	Q12888	TP53BP1	P53350	PLK1	T1654	R1658C	1658	Missense	distal	4	no	10.564	10.982	EPSD	CCLE	10.919	Gain
Other_PLK_PLK1_PLK1_ST	Q12888	TP53BP1	P53350	PLK1	S1656	R1658C	1658	Missense	proximal	2	no	11.479	11.234	EPSD	CCLE	10.919	Down-regulation
Other_PLK_PLK1_PLK1_ST	Q12888	TP53BP1	P53350	PLK1	S1929	A1934V	1934	Missense	distal	5	no	11.665	10.927	EPSD	CCLE	10.919	Down-regulation
Other_PLK_PLK1_PLK1_ST	P08670	VIM	P53350	PLK1	S73	G76E	76	Missense	distal	3	no	10.776	10.953	EPSD	CCLE	10.919	Gain
Other_PLK_PLK1_PLK1_ST	P08670	VIM	P53350	PLK1	S83	G76E	76	Missense	distal	-7	no	12.080	12.716	PhosphoSitePlus;EPSD	CCLE	10.919	Up-regulation
Other_PLK_PLK1_PLK1_ST	P08670	VIM	P53350	PLK1	T202	N201S	201	Missense	proximal	-1	no	11.627	11.768	EPSD	CCLE	10.919	Up-regulation
Other_PLK_PLK1_PLK1_ST	P08670	VIM	P53350	PLK1	S420	N417T	417	Missense	distal	-3	no	10.735	10.922	EPSD	CCLE	10.919	Gain
Other_PLK_PLK1_PLK1_ST	O95425	SVIL	P53350	PLK1	S66	R72Q	72	Missense	distal	6	no	13.619	13.907	EPSD	CCLE	10.919	Up-regulation
Other_PLK_PLK1_PLK1_ST	O95425	SVIL	P53350	PLK1	S261	S259F	259	Missense	proximal	-2	no	12.185	10.627	EPSD	CCLE	10.919	Loss
Other_PLK_PLK1_PLK1_ST	O95425	SVIL	P53350	PLK1	S315	V311M	311	Missense	distal	-4	no	13.327	13.151	EPSD	CCLE	10.919	Down-regulation
Other_PLK_PLK1_PLK1_ST	O95425	SVIL	P53350	PLK1	S315	E308K	308	Missense	distal	-7	no	13.327	13.023	EPSD	CCLE	10.919	Down-regulation
Other_PLK_PLK1_PLK1_ST	O95425	SVIL	P53350	PLK1	T1379	Y1378C	1378	Missense	proximal	-1	no	12.068	9.872	EPSD	CCLE	10.919	Loss
Other_PLK_PLK1_PLK1_ST	Q9UJX2	CDC23	P53350	PLK1	T302	S304F	304	Missense	proximal	2	no	11.238	10.686	EPSD	CCLE	10.919	Loss
Other_PLK_PLK1_PLK1_ST	P30291	WEE1	P53350	PLK1	S67	P64S	64	Missense	distal	-3	no	10.523	10.941	EPSD	CCLE	10.919	Gain
Other_PLK_PLK1_PLK1_ST	P30291	WEE1	P53350	PLK1	S150	D148N	148	Missense	proximal	-2	no	11.455	10.213	EPSD	CCLE	10.919	Loss
Other_PLK_PLK1_PLK1_ST	O60341	KDM1A	P53350	PLK1	T19	E22K	22	Missense	distal	3	no	11.315	11.109	EPSD	CCLE	10.919	Down-regulation
Other_PLK_PLK1_PLK1_ST	O60341	KDM1A	P53350	PLK1	T19	E22G	22	Missense	distal	3	no	11.315	11.138	EPSD	CCLE	10.919	Down-regulation
Other_PLK_PLK1_PLK1_ST	O15350	TP73	P53350	PLK1	T27	P24L	24	Missense	distal	-3	no	13.888	15.080	PhosphoSitePlus	CCLE	10.919	Up-regulation
Other_PLK_PLK1_PLK1_ST	Q9Y265	RUVBL1	P53350	PLK1	S322	R317H	317	Missense	distal	-5	no	11.200	10.397	EPSD	CCLE	10.919	Loss
Other_PLK_PLK1_PLK1_ST	Q00613	HSF1	P53350	PLK1	S248	P243L	243	Missense	distal	-5	no	11.043	11.445	EPSD	CCLE	10.919	Up-regulation
Other_PLK_PLK1_PLK1_ST	Q00613	HSF1	P53350	PLK1	S498	F500Y	500	Missense	proximal	2	no	10.883	11.067	EPSD	CCLE	10.919	Gain
Other_PLK_PLK1_PLK1_ST	Q07817	BCL2L1	P53350	PLK1	S62	S62N	62	Missense	central	0	yes	12.434	0.000	PhosphoSitePlus	CCLE	10.919	Loss
Other_PLK_PLK1_PLK1_ST	P54274	TERF1	P53350	PLK1	T24	M28I	28	Missense	distal	4	no	11.790	11.547	EPSD	CCLE	10.919	Down-regulation
Other_PLK_PLK1_PLK1_ST	Q8IWB6	TEX14	P53350	PLK1	S437	A433T	433	Missense	distal	-4	no	11.879	11.477	PhosphoSitePlus	CCLE	10.919	Down-regulation
Other_PLK_PLK1_PLK1_ST	Q8IWB6	TEX14	P53350	PLK1	S864	E871Q	871	Missense	distal	7	no	12.771	12.824	EPSD	CCLE	10.919	Up-regulation
Other_PLK_PLK1_PLK1_ST	Q8IWB6	TEX14	P53350	PLK1	S864	R868T	868	Missense	distal	4	no	12.771	13.523	EPSD	CCLE	10.919	Up-regulation
Other_PLK_PLK1_PLK1_ST	Q8IWB6	TEX14	P53350	PLK1	T873	T873A	873	Missense	central	0	yes	11.815	0.000	EPSD	CCLE	10.919	Loss
Other_PLK_PLK1_PLK1_ST	Q8IWB6	TEX14	P53350	PLK1	T873	E871Q	871	Missense	proximal	-2	no	11.815	9.156	EPSD	CCLE	10.919	Loss
Other_PLK_PLK1_PLK1_ST	Q8IWB6	TEX14	P53350	PLK1	T873	R868T	868	Missense	distal	-5	no	11.815	11.346	EPSD	CCLE	10.919	Down-regulation
Other_PLK_PLK1_PLK1_ST	Q8IWB6	TEX14	P53350	PLK1	S1385	M1386T	1386	Missense	proximal	1	no	14.815	12.683	EPSD	CCLE	10.919	Down-regulation
Other_PLK_PLK1_PLK1_ST	Q8IWB6	TEX14	P53350	PLK1	S1385	M1386V	1386	Missense	proximal	1	no	14.815	13.659	EPSD	CCLE	10.919	Down-regulation
Other_PLK_PLK1_PLK1_ST	Q8IWB6	TEX14	P53350	PLK1	S1385	S1385C	1385	Missense	central	0	yes	14.815	0.000	EPSD	CCLE	10.919	Loss
Other_PLK_PLK1_PLK1_ST	Q96T23	RSF1	P53350	PLK1	T274	T275I	275	Missense	proximal	1	no	9.872	11.038	EPSD	CCLE	10.919	Gain
Other_PLK_PLK1_PLK1_ST	Q96T23	RSF1	P53350	PLK1	S811	K816R	816	Missense	distal	5	no	10.644	11.269	EPSD	CCLE	10.919	Gain
Other_PLK_PLK1_PLK1_ST	Q96T23	RSF1	P53350	PLK1	T812	K816R	816	Missense	distal	4	no	11.720	11.160	EPSD	CCLE	10.919	Down-regulation
Other_PLK_PLK1_PLK1_ST	Q96T23	RSF1	P53350	PLK1	T817	K816R	816	Missense	proximal	-1	no	11.051	10.690	EPSD	CCLE	10.919	Loss
Other_PLK_PLK1_PLK1_ST	Q96T23	RSF1	P53350	PLK1	S990	Q993E	993	Missense	distal	3	no	13.016	13.124	EPSD	CCLE	10.919	Up-regulation
Other_PLK_PLK1_PLK1_ST	Q96T23	RSF1	P53350	PLK1	S990	D988E	988	Missense	proximal	-2	no	13.016	12.622	EPSD	CCLE	10.919	Down-regulation
Other_PLK_PLK1_PLK1_ST	Q96T23	RSF1	P53350	PLK1	S1180	E1176V	1176	Missense	distal	-4	no	12.544	12.453	EPSD	CCLE	10.919	Down-regulation
Other_PLK_PLK1_PLK1_ST	Q96T23	RSF1	P53350	PLK1	S1221	G1225S	1225	Missense	distal	4	no	12.869	12.955	EPSD	CCLE	10.919	Up-regulation
Other_PLK_PLK1_PLK1_ST	Q96T23	RSF1	P53350	PLK1	S1226	G1225S	1225	Missense	proximal	-1	no	11.104	12.902	EPSD	CCLE	10.919	Up-regulation
Other_PLK_PLK1_PLK1_ST	Q96T23	RSF1	P53350	PLK1	S1229	G1225S	1225	Missense	distal	-4	no	11.434	12.088	EPSD	CCLE	10.919	Up-regulation
Other_PLK_PLK1_PLK1_ST	Q96T23	RSF1	P53350	PLK1	S1310	D1306H	1306	Missense	distal	-4	no	11.127	11.056	EPSD	CCLE	10.919	Down-regulation
Other_PLK_PLK1_PLK1_ST	Q96T23	RSF1	P53350	PLK1	S1364	T1371A	1371	Missense	distal	7	no	13.125	13.165	EPSD	CCLE	10.919	Up-regulation
Other_PLK_PLK1_PLK1_ST	Q8TD19	NEK9	P53350	PLK1	S29	A34T	34	Missense	distal	5	no	11.670	10.499	EPSD	CCLE	10.919	Loss
Other_PLK_PLK1_PLK1_ST	Q8TD19	NEK9	P53350	PLK1	T662	N669D	669	Missense	distal	7	no	12.975	12.893	EPSD	CCLE	10.919	Down-regulation
CMGC_CDK_CDK8_CDK19_ST	O00303	EIF3F	Q9BWU1	CDK19	S46	P43L	43	Missense	distal	-3	no	7.128	6.913	PhosphoSitePlus;EPSD	CCLE	1.856	Down-regulation
CMGC_CDK_CDK8_CDK19_ST	O00303	EIF3F	Q9BWU1	CDK19	S46	S46Y	46	Missense	central	0	yes	7.128	0.000	PhosphoSitePlus;EPSD	CCLE	1.856	Loss
CMGC_CDK_CDK8_CDK19_ST	O00303	EIF3F	Q9BWU1	CDK19	S46	P49S	49	Missense	distal	3	no	7.128	7.362	PhosphoSitePlus;EPSD	CCLE	1.856	Up-regulation
CMGC_CDK_CDK8_CDK19_ST	Q13153	PAK1	Q9BWU1	CDK19	S174	D180G	180	Missense	distal	6	no	7.693	7.667	PhosphoSitePlus	CCLE	1.856	Down-regulation
CMGC_CDK_CDK8_CDK19_ST	Q13153	PAK1	Q9BWU1	CDK19	S174	D178E	178	Missense	distal	4	no	7.693	7.704	PhosphoSitePlus	CCLE	1.856	Up-regulation
CMGC_CDK_CDK8_CDK19_ST	Q13153	PAK1	Q9BWU1	CDK19	S174	E177G	177	Missense	distal	3	no	7.693	7.827	PhosphoSitePlus	CCLE	1.856	Up-regulation
CMGC_CDK_CDK5_CDK5_ST	Q07820	MCL1	Q00535	CDK5	T70	R74L	74	Missense	distal	4	no	17.603	17.503	EPSD	CCLE	8.808	Down-regulation
CMGC_CDK_CDK5_CDK5_ST	Q07820	MCL1	Q00535	CDK5	T70	R74Q	74	Missense	distal	4	no	17.603	17.556	EPSD	CCLE	8.808	Down-regulation
CMGC_CDK_CDK5_CDK5_ST	Q07820	MCL1	Q00535	CDK5	T70	S73P	73	Missense	distal	3	no	17.603	17.622	EPSD	CCLE	8.808	Up-regulation
CMGC_CDK_CDK5_CDK5_ST	Q07820	MCL1	Q00535	CDK5	S73	R74L	74	Missense	proximal	1	no	9.263	6.260	EPSD	CCLE	8.808	Loss
CMGC_CDK_CDK5_CDK5_ST	Q07820	MCL1	Q00535	CDK5	S73	R74Q	74	Missense	proximal	1	no	9.263	9.234	EPSD	CCLE	8.808	Down-regulation
CMGC_CDK_CDK5_CDK5_ST	Q07820	MCL1	Q00535	CDK5	S73	S73P	73	Missense	central	0	yes	9.263	0.000	EPSD	CCLE	8.808	Loss
CMGC_CDK_CDK5_CDK5_ST	Q07820	MCL1	Q00535	CDK5	T92	D88N	88	Missense	distal	-4	no	18.506	18.670	PhosphoSitePlus	CCLE	8.808	Up-regulation
CMGC_CDK_CDK5_CDK5_ST	Q07820	MCL1	Q00535	CDK5	T163	T156R	156	Missense	distal	-7	no	18.116	18.130	EPSD	CCLE	8.808	Up-regulation
CMGC_CDK_CDK5_CDK5_ST	P49023	PXN	Q00535	CDK5	S178	S178N	178	Missense	central	0	yes	17.129	0.000	EPSD	CCLE	8.808	Loss
CMGC_CDK_CDK5_CDK5_ST	P49023	PXN	Q00535	CDK5	S230	V237M	237	Missense	distal	7	no	17.745	17.733	EPSD	CCLE	8.808	Down-regulation
CMGC_CDK_CDK5_CDK5_ST	P49023	PXN	Q00535	CDK5	S244	E241K	241	Missense	distal	-3	no	18.506	18.579	EPSD;PhosphoSitePlus	CCLE	8.808	Up-regulation
CMGC_CDK_CDK5_CDK5_ST	P49023	PXN	Q00535	CDK5	S244	V237M	237	Missense	distal	-7	no	18.506	18.452	EPSD;PhosphoSitePlus	CCLE	8.808	Down-regulation
CMGC_CDK_CDK5_CDK5_ST	P10636	MAPT	Q00535	CDK5	T69	A66V	66	Missense	distal	-3	no	17.225	17.264	EPSD	CCLE	8.808	Up-regulation
CMGC_CDK_CDK5_CDK5_ST	P10636	MAPT	Q00535	CDK5	T111	G107V	107	Missense	distal	-4	no	15.796	16.155	EPSD	CCLE	8.808	Up-regulation
CMGC_CDK_CDK5_CDK5_ST	P10636	MAPT	Q00535	CDK5	S228	D221Y	221	Missense	distal	-7	no	17.027	17.005	EPSD	CCLE	8.808	Down-regulation
CMGC_CDK_CDK5_CDK5_ST	P10636	MAPT	Q00535	CDK5	S228	P234S	234	Missense	distal	6	no	17.027	17.028	EPSD	CCLE	8.808	Up-regulation
CMGC_CDK_CDK5_CDK5_ST	P10636	MAPT	Q00535	CDK5	S232	P234S	234	Missense	proximal	2	no	18.084	18.066	EPSD	CCLE	8.808	Down-regulation
CMGC_CDK_CDK5_CDK5_ST	P10636	MAPT	Q00535	CDK5	S238	P234S	234	Missense	distal	-4	no	18.116	18.463	EPSD	CCLE	8.808	Up-regulation
CMGC_CDK_CDK5_CDK5_ST	P10636	MAPT	Q00535	CDK5	S238	D242H	242	Missense	distal	4	no	18.116	18.154	EPSD	CCLE	8.808	Up-regulation
CMGC_CDK_CDK5_CDK5_ST	P10636	MAPT	Q00535	CDK5	S411	K405R	405	Missense	distal	-6	no	17.541	17.505	EPSD	CCLE	8.808	Down-regulation
CMGC_CDK_CDK5_CDK5_ST	P10636	MAPT	Q00535	CDK5	S438	V442I	442	Missense	distal	4	no	17.434	17.410	EPSD	CCLE	8.808	Down-regulation
CMGC_CDK_CDK5_CDK5_ST	P10636	MAPT	Q00535	CDK5	S447	V442I	442	Missense	distal	-5	no	9.502	9.426	EPSD	CCLE	8.808	Down-regulation
CMGC_CDK_CDK5_CDK5_ST	P10636	MAPT	Q00535	CDK5	S516	R511H	511	Missense	distal	-5	no	17.498	17.325	EPSD	CCLE	8.808	Down-regulation
CMGC_CDK_CDK5_CDK5_ST	P10636	MAPT	Q00535	CDK5	S516	G518S	518	Missense	proximal	2	no	17.498	17.571	EPSD	CCLE	8.808	Up-regulation
CMGC_CDK_CDK5_CDK5_ST	P10636	MAPT	Q00535	CDK5	S519	G518S	518	Missense	proximal	-1	no	17.944	17.948	EPSD	CCLE	8.808	Up-regulation
CMGC_CDK_CDK5_CDK5_ST	P10636	MAPT	Q00535	CDK5	S519	R526L	526	Missense	distal	7	no	17.944	17.929	EPSD	CCLE	8.808	Down-regulation
CMGC_CDK_CDK5_CDK5_ST	P10636	MAPT	Q00535	CDK5	T522	G518S	518	Missense	distal	-4	no	16.384	17.226	EPSD	CCLE	8.808	Up-regulation
CMGC_CDK_CDK5_CDK5_ST	P10636	MAPT	Q00535	CDK5	T522	R526L	526	Missense	distal	4	no	16.384	16.285	EPSD	CCLE	8.808	Down-regulation
CMGC_CDK_CDK5_CDK5_ST	P10636	MAPT	Q00535	CDK5	S525	G518S	518	Missense	distal	-7	no	9.794	9.846	EPSD	CCLE	8.808	Up-regulation
CMGC_CDK_CDK5_CDK5_ST	P10636	MAPT	Q00535	CDK5	S525	R526L	526	Missense	proximal	1	no	9.794	6.791	EPSD	CCLE	8.808	Loss
CMGC_CDK_CDK5_CDK5_ST	P10636	MAPT	Q00535	CDK5	T529	R526L	526	Missense	distal	-3	no	16.130	16.060	EPSD	CCLE	8.808	Down-regulation
CMGC_CDK_CDK5_CDK5_ST	P10636	MAPT	Q00535	CDK5	S552	R559H	559	Missense	distal	7	no	17.986	17.979	EPSD	CCLE	8.808	Down-regulation
CMGC_CDK_CDK5_CDK5_ST	P10636	MAPT	Q00535	CDK5	S713	G706V	706	Missense	distal	-7	no	17.353	17.387	EPSD	CCLE	8.808	Up-regulation
CMGC_CDK_CDK5_CDK5_ST	P10636	MAPT	Q00535	CDK5	S713	S717C	717	Missense	distal	4	no	17.353	17.261	EPSD	CCLE	8.808	Down-regulation
CMGC_CDK_CDK5_CDK5_ST	P10636	MAPT	Q00535	CDK5	S721	S717C	717	Missense	distal	-4	no	18.875	17.850	EPSD	CCLE	8.808	Down-regulation
CMGC_CDK_CDK5_CDK5_ST	P10636	MAPT	Q00535	CDK5	S721	S721C	721	Missense	central	0	yes	18.875	0.000	EPSD	CCLE	8.808	Loss
CMGC_CDK_CDK5_CDK5_ST	P10636	MAPT	Q00535	CDK5	S721	H724R	724	Missense	distal	3	no	18.875	19.894	EPSD	CCLE	8.808	Up-regulation
CMGC_CDK_CDK5_CDK5_ST	P10636	MAPT	Q00535	CDK5	S726	S721C	721	Missense	distal	-5	no	9.203	8.929	EPSD	CCLE	8.808	Down-regulation
CMGC_CDK_CDK5_CDK5_ST	P10636	MAPT	Q00535	CDK5	S726	H724R	724	Missense	proximal	-2	no	9.203	9.464	EPSD	CCLE	8.808	Up-regulation
CMGC_CDK_CDK5_CDK5_ST	P10636	MAPT	Q00535	CDK5	S739	Q741K	741	Missense	proximal	2	no	17.183	17.371	EPSD	CCLE	8.808	Up-regulation
CMGC_CDK_CDK5_CDK5_ST	P42858	HTT	Q00535	CDK5	S118	V115L	115	Missense	distal	-3	no	17.119	17.072	EPSD	CCLE	8.808	Down-regulation
CMGC_CDK_CDK5_CDK5_ST	P42858	HTT	Q00535	CDK5	T341	E344K	344	Missense	distal	3	no	8.713	10.999	EPSD	CCLE	8.808	Gain
CMGC_CDK_CDK5_CDK5_ST	P42858	HTT	Q00535	CDK5	S432	S430L	430	Missense	proximal	-2	no	16.584	16.268	EPSD;PhosphoSitePlus	CCLE	8.808	Down-regulation
CMGC_CDK_CDK5_CDK5_ST	P42858	HTT	Q00535	CDK5	S432	R437I	437	Missense	distal	5	no	16.584	16.431	EPSD;PhosphoSitePlus	CCLE	8.808	Down-regulation
CMGC_CDK_CDK5_CDK5_ST	P42858	HTT	Q00535	CDK5	T486	V484D	484	Missense	proximal	-2	no	17.017	16.864	EPSD	CCLE	8.808	Down-regulation
CMGC_CDK_CDK5_CDK5_ST	P42858	HTT	Q00535	CDK5	T486	S485F	485	Missense	proximal	-1	no	17.017	17.009	EPSD	CCLE	8.808	Down-regulation
CMGC_CDK_CDK5_CDK5_ST	P42858	HTT	Q00535	CDK5	S781	R784H	784	Missense	distal	3	no	9.806	8.787	EPSD	CCLE	8.808	Loss
CMGC_CDK_CDK5_CDK5_ST	P42858	HTT	Q00535	CDK5	S2651	P2653S	2653	Missense	proximal	2	no	18.695	18.677	EPSD	CCLE	8.808	Down-regulation
CMGC_CDK_CDK5_CDK5_ST	P42858	HTT	Q00535	CDK5	S2655	P2653S	2653	Missense	proximal	-2	no	18.601	18.503	EPSD	CCLE	8.808	Down-regulation
CMGC_CDK_CDK5_CDK5_ST	P42858	HTT	Q00535	CDK5	S2655	H2662Y	2662	Missense	distal	7	no	18.601	18.593	EPSD	CCLE	8.808	Down-regulation
CMGC_CDK_CDK5_CDK5_ST	P42858	HTT	Q00535	CDK5	S2659	P2653S	2653	Missense	distal	-6	no	10.320	10.359	EPSD	CCLE	8.808	Up-regulation
CMGC_CDK_CDK5_CDK5_ST	P42858	HTT	Q00535	CDK5	S2659	H2662Y	2662	Missense	distal	3	no	10.320	9.152	EPSD	CCLE	8.808	Down-regulation
CMGC_CDK_CDK5_CDK5_ST	P42858	HTT	Q00535	CDK5	S2934	T2928A	2928	Missense	distal	-6	no	19.397	19.311	EPSD	CCLE	8.808	Down-regulation
CMGC_CDK_CDK5_CDK5_ST	P04150	NR3C1	Q00535	CDK5	S79	K80N	80	Missense	proximal	1	no	-0.122	8.817	EPSD	CCLE	8.808	Gain
CMGC_CDK_CDK5_CDK5_ST	P04150	NR3C1	Q00535	CDK5	S395	S394L	394	Missense	proximal	-1	no	16.926	16.920	EPSD	CCLE	8.808	Down-regulation
CMGC_CDK_CDK5_CDK5_ST	P04150	NR3C1	Q00535	CDK5	S395	G392D	392	Missense	distal	-3	no	16.926	16.927	EPSD	CCLE	8.808	Up-regulation
CMGC_CDK_CDK5_CDK5_ST	Q8NEB9	PIK3C3	Q00535	CDK5	T159	R162K	162	Missense	distal	3	no	19.273	19.592	EPSD;PhosphoSitePlus	CCLE	8.808	Up-regulation
CMGC_CDK_CDK5_CDK5_ST	Q8NEB9	PIK3C3	Q00535	CDK5	S244	E237Q	237	Missense	distal	-7	no	16.661	16.687	EPSD	CCLE	8.808	Up-regulation
CMGC_CDK_CDK5_CDK5_ST	Q8NEB9	PIK3C3	Q00535	CDK5	S244	S249R	249	Missense	distal	5	no	16.661	16.724	EPSD	CCLE	8.808	Up-regulation
CMGC_CDK_CDK5_CDK5_ST	P05067	APP	Q00535	CDK5	T381	E385K	385	Missense	distal	4	no	16.419	16.536	EPSD	CCLE	8.808	Up-regulation
CMGC_CDK_CDK5_CDK5_ST	P05067	APP	Q00535	CDK5	T743	D739V	739	Missense	distal	-4	no	16.502	16.697	EPSD	CCLE	8.808	Up-regulation
CMGC_CDK_CDK5_CDK5_ST	P49418	AMPH	Q00535	CDK5	S293	R298W	298	Missense	distal	5	no	16.929	16.752	EPSD	CCLE	8.808	Down-regulation
CMGC_CDK_CDK5_CDK5_ST	P49418	AMPH	Q00535	CDK5	S293	P294H	294	Missense	proximal	1	no	16.929	-1.583	EPSD	CCLE	8.808	Loss
CMGC_CDK_CDK5_CDK5_ST	P49418	AMPH	Q00535	CDK5	S295	R298W	298	Missense	distal	3	no	10.870	9.180	EPSD	CCLE	8.808	Down-regulation
CMGC_CDK_CDK5_CDK5_ST	P49418	AMPH	Q00535	CDK5	S295	P294H	294	Missense	proximal	-1	no	10.870	10.869	EPSD	CCLE	8.808	Down-regulation
CMGC_CDK_CDK5_CDK5_ST	Q96QB1	DLC1	Q00535	CDK5	T823	S826R	826	Missense	distal	3	no	8.002	9.420	EPSD	CCLE	8.808	Gain
CMGC_CDK_CDK5_CDK5_ST	Q96QB1	DLC1	Q00535	CDK5	S828	S826R	826	Missense	proximal	-2	no	17.712	17.756	EPSD	CCLE	8.808	Up-regulation
CMGC_CDK_CDK5_CDK5_ST	Q3V6T2	CCDC88A	Q00535	CDK5	S233	P234S	234	Missense	proximal	1	no	17.964	6.063	EPSD	CCLE	8.808	Loss
CMGC_CDK_CDK5_CDK5_ST	Q3V6T2	CCDC88A	Q00535	CDK5	S237	P234S	234	Missense	distal	-3	no	17.274	17.268	EPSD	CCLE	8.808	Down-regulation
CMGC_CDK_CDK5_CDK5_ST	Q3V6T2	CCDC88A	Q00535	CDK5	S1020	E1026K	1026	Missense	distal	6	no	17.256	17.274	EPSD	CCLE	8.808	Up-regulation
CMGC_CDK_CDK5_CDK5_ST	Q3V6T2	CCDC88A	Q00535	CDK5	T1421	P1422R	1422	Missense	proximal	1	no	19.246	10.299	EPSD	CCLE	8.808	Down-regulation
CMGC_CDK_CDK5_CDK5_ST	Q3V6T2	CCDC88A	Q00535	CDK5	T1421	S1417Y	1417	Missense	distal	-4	no	19.246	18.265	EPSD	CCLE	8.808	Down-regulation
CMGC_CDK_CDK5_CDK5_ST	P14416	DRD2	Q00535	CDK5	S19	R15K	15	Missense	distal	-4	no	9.063	9.399	EPSD	CCLE	8.808	Up-regulation
CMGC_CDK_CDK5_CDK5_ST	Q13136	PPFIA1	Q00535	CDK5	S150	S150F	150	Missense	central	0	yes	18.030	0.000	EPSD	CCLE	8.808	Loss
CMGC_CDK_CDK5_CDK5_ST	Q13136	PPFIA1	Q00535	CDK5	S520	L521P	521	Missense	proximal	1	no	5.810	17.760	EPSD	CCLE	8.808	Gain
CMGC_CDK_CDK5_CDK5_ST	Q13136	PPFIA1	Q00535	CDK5	T701	P702Q	702	Missense	proximal	1	no	19.303	10.327	PhosphoSitePlus	CCLE	8.808	Down-regulation
CMGC_CDK_CDK5_CDK5_ST	Q13136	PPFIA1	Q00535	CDK5	S708	P702Q	702	Missense	distal	-6	no	19.095	19.083	EPSD	CCLE	8.808	Down-regulation
CMGC_CDK_CDK5_CDK5_ST	Q13136	PPFIA1	Q00535	CDK5	S708	P709A	709	Missense	proximal	1	no	19.095	8.069	EPSD	CCLE	8.808	Loss
CMGC_CDK_CDK5_CDK5_ST	Q13136	PPFIA1	Q00535	CDK5	S1172	S1171A	1171	Missense	proximal	-1	no	17.444	17.439	EPSD	CCLE	8.808	Down-regulation
CMGC_CDK_CDK5_CDK5_ST	Q8IWU2	LMTK2	Q00535	CDK5	T90	P92R	92	Missense	proximal	2	no	16.399	16.481	EPSD	CCLE	8.808	Up-regulation
CMGC_CDK_CDK5_CDK5_ST	Q8IWU2	LMTK2	Q00535	CDK5	S630	V624M	624	Missense	distal	-6	no	18.284	18.179	EPSD	CCLE	8.808	Down-regulation
CMGC_CDK_CDK5_CDK5_ST	Q8IWU2	LMTK2	Q00535	CDK5	T996	T996I	996	Missense	central	0	yes	16.692	0.000	EPSD	CCLE	8.808	Loss
CMGC_CDK_CDK5_CDK5_ST	Q8IWU2	LMTK2	Q00535	CDK5	T1088	T1085A	1085	Missense	distal	-3	no	17.139	17.094	EPSD	CCLE	8.808	Down-regulation
CMGC_CDK_CDK5_CDK5_ST	Q8IWU2	LMTK2	Q00535	CDK5	S1323	D1326E	1326	Missense	distal	3	no	8.852	8.918	EPSD	CCLE	8.808	Up-regulation
CMGC_CDK_CDK5_CDK5_ST	Q8IWU2	LMTK2	Q00535	CDK5	S1397	Y1399N	1399	Missense	proximal	2	no	17.537	17.642	EPSD	CCLE	8.808	Up-regulation
CMGC_CDK_CDK5_CDK5_ST	Q8IWU2	LMTK2	Q00535	CDK5	S1401	Y1399N	1399	Missense	proximal	-2	no	8.735	9.052	EPSD	CCLE	8.808	Gain
CMGC_CDK_CDK5_CDK5_ST	Q8IWU2	LMTK2	Q00535	CDK5	S1450	Y1448H	1448	Missense	proximal	-2	no	18.668	18.880	PhosphoSitePlus	CCLE	8.808	Up-regulation
CMGC_CDK_CDK5_CDK5_ST	Q8IWU2	LMTK2	Q00535	CDK5	S1450	R1456Q	1456	Missense	distal	6	no	18.668	18.657	PhosphoSitePlus	CCLE	8.808	Down-regulation
CMGC_CDK_CDK5_CDK5_ST	Q8IWU2	LMTK2	Q00535	CDK5	S1469	P1475S	1475	Missense	distal	6	no	9.433	9.434	EPSD	CCLE	8.808	Up-regulation
CMGC_CDK_CDK5_CDK5_ST	Q12778	FOXO1	Q00535	CDK5	S329	S325T	325	Missense	distal	-4	no	17.354	16.852	EPSD	CCLE	8.808	Down-regulation
CMGC_CDK_CDK5_CDK5_ST	Q12778	FOXO1	Q00535	CDK5	S432	M431V	431	Missense	proximal	-1	no	18.004	18.009	EPSD	CCLE	8.808	Up-regulation
CMGC_CDK_CDK5_CDK5_ST	Q12778	FOXO1	Q00535	CDK5	S470	I476L	476	Missense	distal	6	no	17.499	17.491	EPSD	CCLE	8.808	Down-regulation
CMGC_CDK_CDK5_CDK5_ST	Q12778	FOXO1	Q00535	CDK5	T478	I476L	476	Missense	proximal	-2	no	17.043	16.950	EPSD	CCLE	8.808	Down-regulation
CMGC_CDK_CDK5_CDK5_ST	P62136	PPP1CA	Q00535	CDK5	S22	V28I	28	Missense	distal	6	no	9.991	9.988	EPSD	CCLE	8.808	Down-regulation
CMGC_CDK_CDK5_CDK5_ST	P62136	PPP1CA	Q00535	CDK5	S22	S22L	22	Missense	central	0	yes	9.991	0.000	EPSD	CCLE	8.808	Loss
CMGC_CDK_CDK5_CDK5_ST	Q9NZ72	STMN3	Q00535	CDK5	S6	Y8C	8	Missense	proximal	2	no	8.996	8.979	EPSD	CCLE	8.808	Down-regulation
CMGC_CDK_CDK5_CDK5_ST	Q9NZ72	STMN3	Q00535	CDK5	S60	E67Q	67	Missense	distal	7	no	17.217	17.222	EPSD	CCLE	8.808	Up-regulation
CMGC_CDK_CDK5_CDK5_ST	Q9NZ72	STMN3	Q00535	CDK5	S65	E67Q	67	Missense	proximal	2	no	17.890	17.951	EPSD	CCLE	8.808	Up-regulation
CMGC_CDK_CDK5_CDK5_ST	Q9NZ72	STMN3	Q00535	CDK5	S68	E67Q	67	Missense	proximal	-1	no	17.056	17.058	PhosphoSitePlus;EPSD	CCLE	8.808	Up-regulation
CMGC_CDK_CDK5_CDK5_ST	Q9NZ72	STMN3	Q00535	CDK5	S73	E67Q	67	Missense	distal	-6	no	19.380	19.416	EPSD;PhosphoSitePlus	CCLE	8.808	Up-regulation
CMGC_CDK_CDK5_CDK5_ST	Q13794	PMAIP1	Q00535	CDK5	S13	A15E	15	Missense	proximal	2	no	21.053	21.045	PhosphoSitePlus	CCLE	8.808	Down-regulation
CMGC_CDK_CDK5_CDK5_ST	Q16643	DBN1	Q00535	CDK5	S73	F67L	67	Missense	distal	-6	no	9.549	9.600	EPSD	CCLE	8.808	Up-regulation
CMGC_CDK_CDK5_CDK5_ST	Q16643	DBN1	Q00535	CDK5	S312	N315S	315	Missense	distal	3	no	16.665	16.860	EPSD	CCLE	8.808	Up-regulation
CMGC_CDK_CDK5_CDK5_ST	Q16643	DBN1	Q00535	CDK5	S312	V310L	310	Missense	proximal	-2	no	16.665	16.431	EPSD	CCLE	8.808	Down-regulation
CMGC_CDK_CDK5_CDK5_ST	Q16643	DBN1	Q00535	CDK5	S312	D309E	309	Missense	distal	-3	no	16.665	16.667	EPSD	CCLE	8.808	Up-regulation
CMGC_CDK_CDK5_CDK5_ST	Q16643	DBN1	Q00535	CDK5	T377	P371S	371	Missense	distal	-6	no	8.934	8.973	EPSD	CCLE	8.808	Up-regulation
CMGC_CDK_CDK5_CDK5_ST	Q16643	DBN1	Q00535	CDK5	T559	P560L	560	Missense	proximal	1	no	16.311	4.361	EPSD	CCLE	8.808	Loss
CMGC_CDK_CDK5_CDK5_ST	O43526	KCNQ2	Q00535	CDK5	S503	A510T	510	Missense	distal	7	no	8.905	8.914	EPSD	CCLE	8.808	Up-regulation
CMGC_CDK_CDK5_CDK5_ST	O43526	KCNQ2	Q00535	CDK5	S731	V733A	733	Missense	proximal	2	no	17.744	17.663	EPSD	CCLE	8.808	Down-regulation
CMGC_CDK_CDK5_CDK5_ST	Q9UM11	FZR1	Q00535	CDK5	S70	R63M	63	Missense	distal	-7	no	17.115	17.043	EPSD	CCLE	8.808	Down-regulation
CMGC_CDK_CDK5_CDK5_ST	Q9UM11	FZR1	Q00535	CDK5	T300	R299S	299	Missense	proximal	-1	no	16.244	16.245	EPSD	CCLE	8.808	Up-regulation
CMGC_CDK_CDK5_CDK5_ST	P12931	SRC	Q00535	CDK5	S12	L18R	18	Missense	distal	6	no	12.092	12.114	EPSD	CCLE	8.808	Up-regulation
CMGC_CDK_CDK5_CDK5_ST	P12931	SRC	Q00535	CDK5	S17	L18R	18	Missense	proximal	1	no	7.548	10.550	EPSD	CCLE	8.808	Gain
CMGC_CDK_CDK5_CDK5_ST	P12931	SRC	Q00535	CDK5	T37	T37P	37	Missense	central	0	yes	18.064	0.000	EPSD	CCLE	8.808	Loss
CMGC_CDK_CDK5_CDK5_ST	P12931	SRC	Q00535	CDK5	S75	P81Q	81	Missense	distal	6	no	19.464	19.461	PhosphoSitePlus	CCLE	8.808	Down-regulation
CMGC_CDK_CDK5_CDK5_ST	P12931	SRC	Q00535	CDK5	S306	P307R	307	Missense	proximal	1	no	18.794	9.847	EPSD	CCLE	8.808	Down-regulation
CMGC_CDK_CDK5_CDK5_ST	O14939	PLD2	Q00535	CDK5	S134	A127V	127	Missense	distal	-7	no	18.193	18.229	PhosphoSitePlus	CCLE	8.808	Up-regulation
CMGC_CDK_CDK5_CDK5_ST	O14939	PLD2	Q00535	CDK5	S484	S481L	481	Missense	distal	-3	no	10.070	10.014	EPSD	CCLE	8.808	Down-regulation
CMGC_CDK_CDK5_CDK5_ST	O14939	PLD2	Q00535	CDK5	S484	S484F	484	Missense	central	0	yes	10.070	0.000	EPSD	CCLE	8.808	Loss
CMGC_CDK_CDK5_CDK5_ST	O14939	PLD2	Q00535	CDK5	S484	R490C	490	Missense	distal	6	no	10.070	10.046	EPSD	CCLE	8.808	Down-regulation
CMGC_CDK_CDK5_CDK5_ST	O14939	PLD2	Q00535	CDK5	T488	S481L	481	Missense	distal	-7	no	18.659	18.603	EPSD	CCLE	8.808	Down-regulation
CMGC_CDK_CDK5_CDK5_ST	O14939	PLD2	Q00535	CDK5	T488	S484F	484	Missense	distal	-4	no	18.659	17.498	EPSD	CCLE	8.808	Down-regulation
CMGC_CDK_CDK5_CDK5_ST	O14939	PLD2	Q00535	CDK5	T488	R490C	490	Missense	proximal	2	no	18.659	18.392	EPSD	CCLE	8.808	Down-regulation
CMGC_CDK_CDK5_CDK5_ST	O14939	PLD2	Q00535	CDK5	S493	R490C	490	Missense	distal	-3	no	19.277	19.199	EPSD	CCLE	8.808	Down-regulation
CMGC_CDK_CDK5_CDK5_ST	O14939	PLD2	Q00535	CDK5	T496	R490C	490	Missense	distal	-6	no	16.454	16.301	EPSD	CCLE	8.808	Down-regulation
CMGC_CDK_CDK5_CDK5_ST	O14939	PLD2	Q00535	CDK5	S888	T886M	886	Missense	proximal	-2	no	17.217	16.783	EPSD	CCLE	8.808	Down-regulation
CMGC_CDK_CDK5_CDK5_ST	Q05397	PTK2	Q00535	CDK5	T13	P8S	8	Missense	distal	-5	no	18.075	18.097	EPSD	CCLE	8.808	Up-regulation
CMGC_CDK_CDK5_CDK5_ST	Q05397	PTK2	Q00535	CDK5	S29	R35Q	35	Missense	distal	6	no	17.967	17.956	EPSD	CCLE	8.808	Down-regulation
CMGC_CDK_CDK5_CDK5_ST	P10275	AR	Q00535	CDK5	S96	Q98R	98	Missense	proximal	2	no	17.005	17.145	EPSD	CCLE	8.808	Up-regulation
CMGC_CDK_CDK5_CDK5_ST	O94811	TPPP	Q00535	CDK5	T14	P15L	15	Missense	proximal	1	no	20.417	8.468	EPSD;PhosphoSitePlus	CCLE	8.808	Loss
CMGC_CDK_CDK5_CDK5_ST	O94811	TPPP	Q00535	CDK5	S18	P15L	15	Missense	distal	-3	no	19.174	19.113	EPSD;PhosphoSitePlus	CCLE	8.808	Down-regulation
CMGC_CDK_CDK5_CDK5_ST	P37231	PPARG	Q00535	CDK5	S273	M280I	280	Missense	distal	7	no	17.838	17.846	PhosphoSitePlus	CCLE	8.808	Up-regulation
CMGC_CDK_CDK5_CDK5_ST	Q9Y210	TRPC6	Q00535	CDK5	S13	G17D	17	Missense	distal	4	no	9.389	9.379	EPSD	CCLE	8.808	Down-regulation
CMGC_CDK_CDK5_CDK5_ST	Q9Y210	TRPC6	Q00535	CDK5	S14	G17D	17	Missense	distal	3	no	19.579	18.928	PhosphoSitePlus	CCLE	8.808	Down-regulation
CMGC_CDK_CDK5_CDK5_ST	Q9NXR1	NDE1	Q00535	CDK5	T191	Q186E	186	Missense	distal	-5	no	16.727	16.632	PhosphoSitePlus	CCLE	8.808	Down-regulation
CMGC_CDK_CDK5_CDK5_ST	Q9NXR1	NDE1	Q00535	CDK5	T215	V212L	212	Missense	distal	-3	no	17.185	17.139	EPSD	CCLE	8.808	Down-regulation
CMGC_CDK_CDK5_CDK5_ST	Q9NXR1	NDE1	Q00535	CDK5	T215	H219L	219	Missense	distal	4	no	17.185	17.125	EPSD	CCLE	8.808	Down-regulation
CMGC_CDK_CDK5_CDK5_ST	Q9NXR1	NDE1	Q00535	CDK5	S333	H329Y	329	Missense	distal	-4	no	17.849	17.549	EPSD	CCLE	8.808	Down-regulation
CMGC_CDK_CDK5_CDK5_ST	P04637	TP53	Q00535	CDK5	S33	E28Q	28	Missense	distal	-5	no	17.666	17.760	EPSD;PhosphoSitePlus	CCLE	8.808	Up-regulation
CMGC_CDK_CDK5_CDK5_ST	Q99490	AGAP2	Q00535	CDK5	S140	R141W	141	Missense	proximal	1	no	9.318	-0.541	EPSD	CCLE	8.808	Loss
CMGC_CDK_CDK5_CDK5_ST	Q99490	AGAP2	Q00535	CDK5	S147	G152D	152	Missense	distal	5	no	17.302	17.273	EPSD	CCLE	8.808	Down-regulation
CMGC_CDK_CDK5_CDK5_ST	Q99490	AGAP2	Q00535	CDK5	S147	R141W	141	Missense	distal	-6	no	17.302	17.196	EPSD	CCLE	8.808	Down-regulation
CMGC_CDK_CDK5_CDK5_ST	Q99490	AGAP2	Q00535	CDK5	S267	A262T	262	Missense	distal	-5	no	20.291	20.447	EPSD	CCLE	8.808	Up-regulation
CMGC_CDK_CDK5_CDK5_ST	Q99490	AGAP2	Q00535	CDK5	S827	R834M	834	Missense	distal	7	no	18.771	18.755	EPSD	CCLE	8.808	Down-regulation
CMGC_CDK_CDK5_CDK5_ST	Q99490	AGAP2	Q00535	CDK5	S1181	A1185T	1185	Missense	distal	4	no	9.577	9.637	EPSD	CCLE	8.808	Up-regulation
CMGC_CDK_CDK5_CDK5_ST	Q14194	CRMP1	Q00535	CDK5	S304	D310N	310	Missense	distal	6	no	17.133	17.139	EPSD	CCLE	8.808	Up-regulation
CMGC_CDK_CDK5_CDK5_ST	Q14194	CRMP1	Q00535	CDK5	S308	D310N	310	Missense	proximal	2	no	18.518	18.578	EPSD	CCLE	8.808	Up-regulation
CMGC_CDK_CDK5_CDK5_ST	P35612	ADD2	Q00535	CDK5	S60	L67V	67	Missense	distal	7	no	15.928	15.938	EPSD	CCLE	8.808	Up-regulation
CMGC_CDK_CDK5_CDK5_ST	P35612	ADD2	Q00535	CDK5	S613	S613R	613	Missense	central	0	yes	17.339	0.000	EPSD	CCLE	8.808	Loss
CMGC_CDK_CDK5_CDK5_ST	P35612	ADD2	Q00535	CDK5	S617	S613R	613	Missense	distal	-4	no	19.900	19.438	EPSD;PhosphoSitePlus	CCLE	8.808	Down-regulation
CMGC_CDK_CDK5_CDK5_ST	P35612	ADD2	Q00535	CDK5	S693	G690A	690	Missense	distal	-3	no	18.849	18.843	EPSD	CCLE	8.808	Down-regulation
CMGC_CDK_CDK5_CDK5_ST	P35612	ADD2	Q00535	CDK5	S697	G690A	690	Missense	distal	-7	no	19.283	19.281	EPSD	CCLE	8.808	Down-regulation
CMGC_CDK_CDK5_CDK5_ST	O00429	DNM1L	Q00535	CDK5	S529	R522T	522	Missense	distal	-7	no	11.576	11.561	EPSD	CCLE	8.808	Down-regulation
CMGC_CDK_CDK5_CDK5_ST	O00429	DNM1L	Q00535	CDK5	S548	S548P	548	Missense	central	0	yes	17.721	0.000	EPSD	CCLE	8.808	Loss
CMGC_CDK_CDK5_CDK5_ST	Q8IV63	VRK3	Q00535	CDK5	S71	V69I	69	Missense	proximal	-2	no	17.408	17.267	EPSD	CCLE	8.808	Down-regulation
CMGC_CDK_CDK5_CDK5_ST	Q8IV63	VRK3	Q00535	CDK5	S122	Q124H	124	Missense	proximal	2	no	19.149	19.173	EPSD	CCLE	8.808	Up-regulation
CMGC_CDK_CDK5_CDK5_ST	Q8IV63	VRK3	Q00535	CDK5	S129	Q124H	124	Missense	distal	-5	no	19.829	19.817	EPSD	CCLE	8.808	Down-regulation
CMGC_CDK_CDK5_CDK5_ST	Q8IV63	VRK3	Q00535	CDK5	S348	E355Q	355	Missense	distal	7	no	17.815	17.820	EPSD	CCLE	8.808	Up-regulation
CMGC_CDK_CDK5_CDK5_ST	Q16665	HIF1A	Q00535	CDK5	S14	K10E	10	Missense	distal	-4	no	9.177	8.674	EPSD	CCLE	8.808	Loss
CMGC_CDK_CDK5_CDK5_ST	Q16665	HIF1A	Q00535	CDK5	S14	I13M	13	Missense	proximal	-1	no	9.177	9.173	EPSD	CCLE	8.808	Down-regulation
CMGC_CDK_CDK5_CDK5_ST	Q16665	HIF1A	Q00535	CDK5	S28	S34Y	34	Missense	distal	6	no	9.582	9.568	EPSD	CCLE	8.808	Down-regulation
CMGC_CDK_CDK5_CDK5_ST	Q15717	ELAVL1	Q00535	CDK5	S202	A204V	204	Missense	proximal	2	no	19.114	19.195	PhosphoSitePlus	CCLE	8.808	Up-regulation
CMGC_CDK_CDK5_CDK5_ST	Q15717	ELAVL1	Q00535	CDK5	S221	G224D	224	Missense	distal	3	no	17.779	17.128	EPSD	CCLE	8.808	Down-regulation
CMGC_CDK_CDK5_CDK5_ST	Q14814	MEF2D	Q00535	CDK5	S180	P181S	181	Missense	proximal	1	no	17.294	5.393	EPSD	CCLE	8.808	Loss
CMGC_CDK_CDK5_CDK5_ST	Q14814	MEF2D	Q00535	CDK5	S192	P196S	196	Missense	distal	4	no	17.011	17.013	EPSD	CCLE	8.808	Up-regulation
CMGC_CDK_CDK5_CDK5_ST	Q14814	MEF2D	Q00535	CDK5	S242	L243P	243	Missense	proximal	1	no	6.890	18.840	EPSD	CCLE	8.808	Gain
CMGC_CDK_CDK5_CDK5_ST	Q14814	MEF2D	Q00535	CDK5	S444	V443A	443	Missense	proximal	-1	no	20.530	20.527	PhosphoSitePlus	CCLE	8.808	Down-regulation
CMGC_CDK_CDK5_CDK5_ST	Q14814	MEF2D	Q00535	CDK5	S444	I438N	438	Missense	distal	-6	no	20.530	20.544	PhosphoSitePlus	CCLE	8.808	Up-regulation
CMGC_CDK_CDK5_CDK5_ST	Q14814	MEF2D	Q00535	CDK5	S446	V443A	443	Missense	distal	-3	no	10.776	10.738	EPSD	CCLE	8.808	Down-regulation
CMGC_CDK_CDK5_CDK5_ST	Q14814	MEF2D	Q00535	CDK5	S450	V443A	443	Missense	distal	-7	no	18.610	18.574	EPSD	CCLE	8.808	Down-regulation
CMGC_CDK_CDK5_CDK5_ST	Q14814	MEF2D	Q00535	CDK5	S472	A474S	474	Missense	proximal	2	no	16.962	17.057	EPSD	CCLE	8.808	Up-regulation
CMGC_CDK_CDK5_CDK5_ST	Q96KR7	PHACTR3	Q00535	CDK5	S156	P157S	157	Missense	proximal	1	no	17.190	5.289	EPSD	CCLE	8.808	Loss
CMGC_CDK_CDK5_CDK5_ST	Q96KR7	PHACTR3	Q00535	CDK5	S278	T283K	283	Missense	distal	5	no	17.242	17.380	EPSD	CCLE	8.808	Up-regulation
CMGC_CDK_CDK5_CDK5_ST	Q96KR7	PHACTR3	Q00535	CDK5	S291	R292H	292	Missense	proximal	1	no	8.927	-0.638	EPSD	CCLE	8.808	Loss
CMGC_CDK_CDK5_CDK5_ST	P01106	MYC	Q00535	CDK5	T8	R10T	10	Missense	proximal	2	no	8.962	8.888	EPSD	CCLE	8.808	Down-regulation
CMGC_CDK_CDK5_CDK5_ST	P01106	MYC	Q00535	CDK5	T8	N11K	11	Missense	distal	3	no	8.962	10.895	EPSD	CCLE	8.808	Up-regulation
CMGC_CDK_CDK5_CDK5_ST	P01106	MYC	Q00535	CDK5	T58	E54K	54	Missense	distal	-4	no	15.918	16.421	EPSD	CCLE	8.808	Up-regulation
CMGC_CDK_CDK5_CDK5_ST	P01106	MYC	Q00535	CDK5	T58	P57H	57	Missense	proximal	-1	no	15.918	15.917	EPSD	CCLE	8.808	Down-regulation
CMGC_CDK_CDK5_CDK5_ST	P01106	MYC	Q00535	CDK5	S62	P57H	57	Missense	distal	-5	no	19.881	19.811	PhosphoSitePlus	CCLE	8.808	Down-regulation
CMGC_CDK_CDK5_CDK5_ST	P01106	MYC	Q00535	CDK5	S62	L69I	69	Missense	distal	7	no	19.881	19.887	PhosphoSitePlus	CCLE	8.808	Up-regulation
CMGC_CDK_CDK5_CDK5_ST	P01106	MYC	Q00535	CDK5	S64	P57H	57	Missense	distal	-7	no	9.314	9.287	EPSD	CCLE	8.808	Down-regulation
CMGC_CDK_CDK5_CDK5_ST	P01106	MYC	Q00535	CDK5	S64	L69I	69	Missense	distal	5	no	9.314	9.409	EPSD	CCLE	8.808	Up-regulation
CMGC_CDK_CDK5_CDK5_ST	P01106	MYC	Q00535	CDK5	S71	L69I	69	Missense	proximal	-2	no	17.722	17.815	EPSD	CCLE	8.808	Up-regulation
CMGC_CDK_CDK5_CDK5_ST	P01106	MYC	Q00535	CDK5	S71	Y74S	74	Missense	distal	3	no	17.722	18.490	EPSD	CCLE	8.808	Up-regulation
CMGC_CDK_CDK5_CDK5_ST	P01106	MYC	Q00535	CDK5	S71	T78R	78	Missense	distal	7	no	17.722	17.725	EPSD	CCLE	8.808	Up-regulation
CMGC_CDK_CDK5_CDK5_ST	P01106	MYC	Q00535	CDK5	T78	Y74S	74	Missense	distal	-4	no	16.878	17.859	EPSD	CCLE	8.808	Up-regulation
CMGC_CDK_CDK5_CDK5_ST	P01106	MYC	Q00535	CDK5	T78	T78R	78	Missense	central	0	yes	16.878	0.000	EPSD	CCLE	8.808	Loss
CMGC_CDK_CDK5_CDK5_ST	P01106	MYC	Q00535	CDK5	T78	L82F	82	Missense	distal	4	no	16.878	16.849	EPSD	CCLE	8.808	Down-regulation
CMGC_CDK_CDK5_CDK5_ST	P01106	MYC	Q00535	CDK5	S204	K206T	206	Missense	proximal	2	no	18.353	18.230	EPSD	CCLE	8.808	Down-regulation
CMGC_CDK_CDK5_CDK5_ST	Q14195	DPYSL3	Q00535	CDK5	S308	D315N	315	Missense	distal	7	no	18.614	18.619	EPSD	CCLE	8.808	Up-regulation
CMGC_CDK_CDK5_CDK5_ST	P09874	PARP1	Q00535	CDK5	T325	R330Q	330	Missense	distal	5	no	8.912	8.787	EPSD	CCLE	8.808	Loss
CMGC_CDK_CDK5_CDK5_ST	P09874	PARP1	Q00535	CDK5	T327	R330Q	330	Missense	distal	3	no	18.538	16.735	EPSD	CCLE	8.808	Down-regulation
CMGC_CDK_CDK5_CDK5_ST	P09874	PARP1	Q00535	CDK5	T335	R340G	340	Missense	distal	5	no	17.237	17.071	EPSD	CCLE	8.808	Down-regulation
CMGC_CDK_CDK5_CDK5_ST	P09874	PARP1	Q00535	CDK5	T335	R330Q	330	Missense	distal	-5	no	17.237	17.076	EPSD	CCLE	8.808	Down-regulation
CMGC_CDK_CDK5_CDK5_ST	P09874	PARP1	Q00535	CDK5	T368	A367D	367	Missense	proximal	-1	no	17.579	17.580	EPSD	CCLE	8.808	Up-regulation
CMGC_CDK_CDK5_CDK5_ST	P27695	APEX1	Q00535	CDK5	T260	A263P	263	Missense	distal	3	no	17.060	17.305	EPSD	CCLE	8.808	Up-regulation
CMGC_CDK_CDK5_CDK5_ST	P06400	RB1	Q00535	CDK5	T373	M379T	379	Missense	distal	6	no	18.227	18.244	EPSD	CCLE	8.808	Up-regulation
CMGC_CDK_CDK5_CDK5_ST	P06400	RB1	Q00535	CDK5	S608	P609H	609	Missense	proximal	1	no	18.641	0.129	EPSD	CCLE	8.808	Loss
CMGC_CDK_CDK5_CDK5_ST	P06400	RB1	Q00535	CDK5	S612	P609H	609	Missense	distal	-3	no	20.210	20.188	EPSD	CCLE	8.808	Down-regulation
CMGC_CDK_CDK5_CDK5_ST	Q16236	NFE2L2	Q00535	CDK5	S301	P300S	300	Missense	proximal	-1	no	18.352	18.353	EPSD	CCLE	8.808	Up-regulation
CMGC_CDK_CDK5_CDK5_ST	P35968	KDR	Q00535	CDK5	S229	Y224H	224	Missense	distal	-5	no	18.514	18.671	PhosphoSitePlus	CCLE	8.808	Up-regulation
CMGC_CDK_CDK5_CDK5_ST	P35968	KDR	Q00535	CDK5	S1279	V1286M	1286	Missense	distal	7	no	16.619	16.607	EPSD	CCLE	8.808	Down-regulation
CMGC_CDK_CDK5_CDK5_ST	P35968	KDR	Q00535	CDK5	S1279	T1276N	1276	Missense	distal	-3	no	16.619	16.603	EPSD	CCLE	8.808	Down-regulation
CMGC_CDK_CDK5_CDK5_ST	P35968	KDR	Q00535	CDK5	S1290	V1286M	1286	Missense	distal	-4	no	9.427	8.839	EPSD	CCLE	8.808	Down-regulation
CMGC_CDK_CDK5_CDK5_ST	P40763	STAT3	Q00535	CDK5	T196	Q202K	202	Missense	distal	6	no	10.155	10.168	EPSD	CCLE	8.808	Up-regulation
CMGC_CDK_CDK5_CDK5_ST	Q05193	DNM1	Q00535	CDK5	S822	P816S	816	Missense	distal	-6	no	17.194	17.233	EPSD	CCLE	8.808	Up-regulation
CMGC_CDK_CDK5_CDK5_ST	Q96C19	EFHD2	Q00535	CDK5	T24	E19K	19	Missense	distal	-5	no	17.555	17.845	EPSD	CCLE	8.808	Up-regulation
CMGC_CDK_CDK5_CDK5_ST	Q96C19	EFHD2	Q00535	CDK5	S76	Y83C	83	Missense	distal	7	no	9.599	9.598	EPSD	CCLE	8.808	Down-regulation
CMGC_CDK_CDK5_CDK5_ST	Q02078	MEF2A	Q00535	CDK5	S98	S98N	98	Missense	central	0	yes	16.877	0.000	EPSD	CCLE	8.808	Loss
CMGC_CDK_CDK5_CDK5_ST	Q02078	MEF2A	Q00535	CDK5	S98	C96Y	96	Missense	proximal	-2	no	16.877	16.920	EPSD	CCLE	8.808	Up-regulation
CMGC_CDK_CDK5_CDK5_ST	Q00535	CDK5	Q00535	CDK5	S72	V69I	69	Missense	distal	-3	no	9.325	9.310	EPSD	CCLE	8.808	Down-regulation
CMGC_CDK_CDK5_CDK5_ST	P41236	PPP1R2	Q00535	CDK5	T73	M79T	79	Missense	distal	6	no	17.425	17.442	PhosphoSitePlus	CCLE	8.808	Up-regulation
CMGC_CDK_CDK5_CDK5_ST	P41236	PPP1R2	Q00535	CDK5	T73	M78I	78	Missense	distal	5	no	17.425	17.539	PhosphoSitePlus	CCLE	8.808	Up-regulation
CMGC_CDK_CDK5_CDK5_ST	P29474	NOS3	Q00535	CDK5	T33	A35D	35	Missense	proximal	2	no	17.026	17.015	EPSD	CCLE	8.808	Down-regulation
CMGC_CDK_CDK5_CDK5_ST	P29474	NOS3	Q00535	CDK5	T33	S39N	39	Missense	distal	6	no	17.026	17.021	EPSD	CCLE	8.808	Down-regulation
CMGC_CDK_CDK5_CDK5_ST	P29474	NOS3	Q00535	CDK5	S39	A35D	35	Missense	distal	-4	no	8.650	8.876	EPSD	CCLE	8.808	Gain
CMGC_CDK_CDK5_CDK5_ST	P29474	NOS3	Q00535	CDK5	S53	A49T	49	Missense	distal	-4	no	17.923	18.322	EPSD	CCLE	8.808	Up-regulation
CMGC_CDK_CDK5_CDK5_ST	P29474	NOS3	Q00535	CDK5	S114	P115S	115	Missense	proximal	1	no	17.821	5.920	PhosphoSitePlus	CCLE	8.808	Loss
CMGC_CDK_CDK5_CDK5_ST	P29474	NOS3	Q00535	CDK5	S981	T978M	978	Missense	distal	-3	no	10.918	10.855	EPSD	CCLE	8.808	Down-regulation
CMGC_CDK_CDK5_CDK5_ST	P26358	DNMT1	Q00535	CDK5	T137	T137R	137	Missense	central	0	yes	19.519	0.000	EPSD	CCLE	8.808	Loss
CMGC_CDK_CDK5_CDK5_ST	P26358	DNMT1	Q00535	CDK5	S209	E211A	211	Missense	proximal	2	no	9.948	9.956	EPSD	CCLE	8.808	Up-regulation
CMGC_CDK_CDK5_CDK5_ST	P26358	DNMT1	Q00535	CDK5	S288	K291E	291	Missense	distal	3	no	10.524	8.238	EPSD	CCLE	8.808	Loss
CMGC_CDK_CDK5_CDK5_ST	P26358	DNMT1	Q00535	CDK5	S288	K285Q	285	Missense	distal	-3	no	10.524	10.478	EPSD	CCLE	8.808	Down-regulation
CMGC_CDK_CDK5_CDK5_ST	P26358	DNMT1	Q00535	CDK5	T328	K335R	335	Missense	distal	7	no	17.001	16.996	EPSD	CCLE	8.808	Down-regulation
CMGC_CDK_CDK5_CDK5_ST	P26358	DNMT1	Q00535	CDK5	T328	T333M	333	Missense	distal	5	no	17.001	16.797	EPSD	CCLE	8.808	Down-regulation
CMGC_CDK_CDK5_CDK5_ST	P26358	DNMT1	Q00535	CDK5	S878	A874T	874	Missense	distal	-4	no	18.929	19.328	EPSD	CCLE	8.808	Up-regulation
CMGC_CDK_CDK5_CDK5_ST	P26358	DNMT1	Q00535	CDK5	S1105	P1099S	1099	Missense	distal	-6	no	18.070	18.109	EPSD	CCLE	8.808	Up-regulation
CMGC_CDK_CDK5_CDK5_ST	Q13315	ATM	Q00535	CDK5	S89	Q95L	95	Missense	distal	6	no	11.716	11.705	EPSD	CCLE	8.808	Down-regulation
CMGC_CDK_CDK5_CDK5_ST	Q13315	ATM	Q00535	CDK5	S1981	S1987Y	1987	Missense	distal	6	no	9.165	9.151	EPSD	CCLE	8.808	Down-regulation
CMGC_CDK_CDK5_CDK5_ST	Q9UQL6	HDAC5	Q00535	CDK5	S3	G9R	9	Missense	distal	6	no	16.820	16.837	EPSD	CCLE	8.808	Up-regulation
CMGC_CDK_CDK5_CDK5_ST	Q9UQL6	HDAC5	Q00535	CDK5	T23	S24P	24	Missense	proximal	1	no	6.426	18.327	EPSD	CCLE	8.808	Gain
CMGC_CDK_CDK5_CDK5_ST	Q9UQL6	HDAC5	Q00535	CDK5	S1108	E1113Q	1113	Missense	distal	5	no	17.888	17.939	EPSD	CCLE	8.808	Up-regulation
CMGC_CDK_CDK5_CDK5_ST	Q9UQL6	HDAC5	Q00535	CDK5	S1108	S1108G	1108	Missense	central	0	yes	17.888	0.000	EPSD	CCLE	8.808	Loss
CMGC_CDK_CDK5_CDK5_ST	Q5S007	LRRK2	Q00535	CDK5	T213	I207V	207	Missense	distal	-6	no	9.203	9.230	EPSD	CCLE	8.808	Up-regulation
CMGC_CDK_CDK5_CDK5_ST	Q5S007	LRRK2	Q00535	CDK5	S1457	A1464G	1464	Missense	distal	7	no	9.176	9.177	EPSD	CCLE	8.808	Up-regulation
CMGC_CDK_CDK5_CDK5_ST	O15169	AXIN1	Q00535	CDK5	T481	R477C	477	Missense	distal	-4	no	19.083	18.520	PhosphoSitePlus	CCLE	8.808	Down-regulation
CMGC_CDK_CDK5_CDK5_ST	O15169	AXIN1	Q00535	CDK5	S493	D495N	495	Missense	proximal	2	no	17.697	17.757	EPSD	CCLE	8.808	Up-regulation
CMGC_CDK_CDK5_CDK5_ST	O15169	AXIN1	Q00535	CDK5	S542	H537R	537	Missense	distal	-5	no	8.891	9.063	EPSD	CCLE	8.808	Up-regulation
CMGC_CDK_CDK5_CDK5_ST	P02545	LMNA	Q00535	CDK5	S390	R388H	388	Missense	proximal	-2	no	18.452	18.190	EPSD	CCLE	8.808	Down-regulation
CMGC_CDK_CDK5_CDK5_ST	P02545	LMNA	Q00535	CDK5	S392	R388H	388	Missense	distal	-4	no	18.400	18.180	PhosphoSitePlus	CCLE	8.808	Down-regulation
CMGC_CDK_CDK5_CDK5_ST	P02545	LMNA	Q00535	CDK5	S395	R388H	388	Missense	distal	-7	no	9.159	9.128	EPSD	CCLE	8.808	Down-regulation
CMGC_CDK_CDK5_CDK5_ST	P02545	LMNA	Q00535	CDK5	S426	R427C	427	Missense	proximal	1	no	8.902	-2.824	EPSD	CCLE	8.808	Loss
CMGC_CDK_CDK5_CDK5_ST	P02545	LMNA	Q00535	CDK5	S507	D511N	511	Missense	distal	4	no	17.593	17.624	EPSD	CCLE	8.808	Up-regulation
CMGC_CDK_CDK5_CDK5_ST	P02545	LMNA	Q00535	CDK5	S568	H569P	569	Missense	proximal	1	no	-1.662	16.850	EPSD	CCLE	8.808	Gain
CMGC_CDK_CDK5_CDK5_ST	P02545	LMNA	Q00535	CDK5	T655	P658S	658	Missense	distal	3	no	9.686	9.666	EPSD	CCLE	8.808	Down-regulation
CMGC_CDK_CDK5_CDK5_ST	P02545	LMNA	Q00535	CDK5	S657	P658S	658	Missense	proximal	1	no	18.641	6.740	EPSD	CCLE	8.808	Loss
CMGC_CDK_CDK5_CDK5_ST	Q9Y490	TLN1	Q00535	CDK5	S588	E586K	586	Missense	proximal	-2	no	8.554	8.967	EPSD	CCLE	8.808	Gain
CMGC_CDK_CDK5_CDK5_ST	O94916	NFAT5	Q00535	CDK5	T608	P609T	609	Missense	proximal	1	no	17.221	6.733	EPSD	CCLE	8.808	Loss
CMGC_CDK_CDK5_CDK5_ST	O94916	NFAT5	Q00535	CDK5	T608	E615V	615	Missense	distal	7	no	17.221	17.227	EPSD	CCLE	8.808	Up-regulation
CMGC_CDK_CDK5_CDK5_ST	O94916	NFAT5	Q00535	CDK5	T631	S630L	630	Missense	proximal	-1	no	9.031	9.025	EPSD	CCLE	8.808	Down-regulation
CMGC_CDK_CDK5_CDK5_ST	O94916	NFAT5	Q00535	CDK5	S649	S649L	649	Missense	central	0	yes	16.674	0.000	EPSD	CCLE	8.808	Loss
CMGC_CDK_CDK5_CDK5_ST	O94916	NFAT5	Q00535	CDK5	S1247	A1240V	1240	Missense	distal	-7	no	9.010	9.045	EPSD	CCLE	8.808	Up-regulation
CMGC_CDK_CDK5_CDK5_ST	Q15833	STXBP2	Q00535	CDK5	T449	G452R	452	Missense	distal	3	no	7.857	9.239	EPSD	CCLE	8.808	Gain
CMGC_CDK_CDK5_CDK5_ST	Q15833	STXBP2	Q00535	CDK5	S458	G452R	452	Missense	distal	-6	no	8.894	8.995	EPSD	CCLE	8.808	Up-regulation
CMGC_CDK_CDK5_CDK5_ST	Q15833	STXBP2	Q00535	CDK5	S473	Q471R	471	Missense	proximal	-2	no	9.688	9.825	EPSD	CCLE	8.808	Up-regulation
CMGC_CDK_CDK5_CDK5_ST	Q15833	STXBP2	Q00535	CDK5	S473	R474C	474	Missense	proximal	1	no	9.688	-2.038	EPSD	CCLE	8.808	Loss
CMGC_CDK_CDK5_CDK5_ST	Q15833	STXBP2	Q00535	CDK5	S508	A503D	503	Missense	distal	-5	no	8.814	8.830	EPSD	CCLE	8.808	Up-regulation
CMGC_CDK_CDK5_CDK5_ST	Q15833	STXBP2	Q00535	CDK5	T572	R575L	575	Missense	distal	3	no	19.849	17.379	PhosphoSitePlus	CCLE	8.808	Down-regulation
CMGC_CDK_CDK5_CDK5_ST	P08670	VIM	Q00535	CDK5	S7	S8P	8	Missense	proximal	1	no	7.046	18.947	EPSD	CCLE	8.808	Gain
CMGC_CDK_CDK5_CDK5_ST	P08670	VIM	Q00535	CDK5	S9	S8P	8	Missense	proximal	-1	no	8.979	8.978	EPSD	CCLE	8.808	Down-regulation
CAMK_CAMK1_PNCK_ST	P08238	HSP90AB1	Q6P2M8	PNCK	T94	N101S	101	Missense	distal	7	no	2.016	1.647	EPSD	CCLE	1.882	Loss
CAMK_CAMK1_PNCK_ST	P08238	HSP90AB1	Q6P2M8	PNCK	S124	G120D	120	Missense	distal	-4	no	2.320	2.209	EPSD	CCLE	1.882	Down-regulation
CAMK_CAMK1_PNCK_ST	P08238	HSP90AB1	Q6P2M8	PNCK	S434	F433L	433	Missense	proximal	-1	no	1.911	1.321	EPSD	CCLE	1.882	Loss
CAMK_CAMK1_PNCK_ST	P07900	HSP90AA1	Q6P2M8	PNCK	S406	I408F	408	Missense	proximal	2	no	2.418	1.995	EPSD	CCLE	1.882	Down-regulation
CAMK_CAMK1_PNCK_ST	P07900	HSP90AA1	Q6P2M8	PNCK	S589	L592S	592	Missense	distal	3	no	2.057	1.512	EPSD	CCLE	1.882	Loss
CAMK_CAMK1_PNCK_ST	P07900	HSP90AA1	Q6P2M8	PNCK	T624	K631N	631	Missense	distal	7	no	7.043	6.945	EPSD;PhosphoSitePlus	CCLE	1.882	Down-regulation
CAMK_CAMK1_PNCK_ST	P07900	HSP90AA1	Q6P2M8	PNCK	T624	M628K	628	Missense	distal	4	no	7.043	6.947	EPSD;PhosphoSitePlus	CCLE	1.882	Down-regulation
CAMK_CAMK1_PNCK_ST	P07900	HSP90AA1	Q6P2M8	PNCK	T624	A618T	618	Missense	distal	-6	no	7.043	7.212	EPSD;PhosphoSitePlus	CCLE	1.882	Up-regulation
CAMK_CAMK1_PNCK_ST	O43432	EIF4G3	Q6P2M8	PNCK	T417	P415L	415	Missense	proximal	-2	no	1.780	2.011	EPSD	CCLE	1.882	Gain
CAMK_PKD_PRKD2_ST	P50552	VASP	Q9BZL6	PRKD2	S322	S324C	324	Missense	proximal	2	no	3.733	3.721	EPSD;PhosphoSitePlus	CCLE	1.791	Down-regulation
CAMK_PKD_PRKD2_ST	P50552	VASP	Q9BZL6	PRKD2	S323	S324C	324	Missense	proximal	1	no	1.795	1.498	EPSD	CCLE	1.791	Loss
CAMK_PKD_PRKD2_ST	Q8WYL5	SSH1	Q9BZL6	PRKD2	S400	R399P	399	Missense	proximal	-1	no	1.957	1.913	EPSD	CCLE	1.791	Down-regulation
CAMK_PKD_PRKD2_ST	Q8WYL5	SSH1	Q9BZL6	PRKD2	S402	R399P	399	Missense	distal	-3	no	1.829	0.783	EPSD	CCLE	1.791	Loss
CAMK_PKD_PRKD2_ST	Q8WYL5	SSH1	Q9BZL6	PRKD2	S428	R431C	431	Missense	distal	3	no	2.263	2.235	EPSD	CCLE	1.791	Down-regulation
CAMK_PKD_PRKD2_ST	Q8WYL5	SSH1	Q9BZL6	PRKD2	S528	T526A	526	Missense	proximal	-2	no	1.895	1.886	EPSD	CCLE	1.791	Down-regulation
CAMK_PKD_PRKD2_ST	Q8WYL5	SSH1	Q9BZL6	PRKD2	S894	A888T	888	Missense	distal	-6	no	2.185	2.186	EPSD	CCLE	1.791	Up-regulation
CAMK_PKD_PRKD2_ST	Q9UQL6	HDAC5	Q9BZL6	PRKD2	S713	R710G	710	Missense	distal	-3	no	1.970	0.877	EPSD	CCLE	1.791	Loss
CAMK_PKD_PRKD2_ST	Q9UQL6	HDAC5	Q9BZL6	PRKD2	S1108	E1113Q	1113	Missense	distal	5	no	2.046	2.064	EPSD	CCLE	1.791	Up-regulation
CAMK_PKD_PRKD2_ST	Q9UQL6	HDAC5	Q9BZL6	PRKD2	S1108	S1108G	1108	Missense	central	0	yes	2.046	0.000	EPSD	CCLE	1.791	Loss
CAMK_PKD_PRKD2_ST	Q13563	PKD2	Q9BZL6	PRKD2	S122	E117D	117	Missense	distal	-5	no	1.875	2.047	EPSD	CCLE	1.791	Up-regulation
CAMK_PKD_PRKD2_ST	Q9UBF8	PI4KB	Q9BZL6	PRKD2	S294	S287G	287	Missense	distal	-7	no	3.105	3.003	PhosphoSitePlus	CCLE	1.791	Down-regulation
CAMK_PKD_PRKD2_ST	Q9UBF8	PI4KB	Q9BZL6	PRKD2	T341	R338W	338	Missense	distal	-3	no	2.305	1.423	EPSD	CCLE	1.791	Loss
CAMK_PKD_PRKD2_ST	Q9UBF8	PI4KB	Q9BZL6	PRKD2	S511	P518L	518	Missense	distal	7	no	2.376	2.380	EPSD	CCLE	1.791	Up-regulation
CAMK_PKD_PRKD2_ST	Q9BZL6	PRKD2	Q9BZL6	PRKD2	S111	D114Y	114	Missense	distal	3	no	1.864	1.867	EPSD	CCLE	1.791	Up-regulation
CAMK_PKD_PRKD2_ST	Q9BZL6	PRKD2	Q9BZL6	PRKD2	S197	A202T	202	Missense	distal	5	no	2.449	2.436	EPSD	CCLE	1.791	Down-regulation
CAMK_PKD_PRKD2_ST	Q9BZL6	PRKD2	Q9BZL6	PRKD2	S206	A202T	202	Missense	distal	-4	no	1.819	1.824	EPSD	CCLE	1.791	Up-regulation
CAMK_PKD_PRKD2_ST	Q13671	RIN1	Q9BZL6	PRKD2	S291	E290K	290	Missense	proximal	-1	no	2.183	2.250	EPSD	CCLE	1.791	Up-regulation
CAMK_PKD_PRKD2_ST	Q13671	RIN1	Q9BZL6	PRKD2	S291	Y295C	295	Missense	distal	4	no	2.183	2.137	EPSD	CCLE	1.791	Down-regulation
CAMK_PKD_PRKD2_ST	Q13671	RIN1	Q9BZL6	PRKD2	S292	E290K	290	Missense	proximal	-2	no	3.868	3.875	PhosphoSitePlus	CCLE	1.791	Up-regulation
CAMK_PKD_PRKD2_ST	Q13671	RIN1	Q9BZL6	PRKD2	S292	Y295C	295	Missense	distal	3	no	3.868	3.863	PhosphoSitePlus	CCLE	1.791	Down-regulation
CAMK_CAMK2_CAMK2B_ST	O14490	DLGAP1	Q13554	CAMK2B	S375	R372W	372	Missense	distal	-3	no	140.853	61.053	EPSD	CCLE	127.946	Loss
CAMK_CAMK2_CAMK2B_ST	O14490	DLGAP1	Q13554	CAMK2B	S440	M442R	442	Missense	proximal	2	no	148.104	147.147	EPSD	CCLE	127.946	Down-regulation
CAMK_CAMK2_CAMK2B_ST	O14490	DLGAP1	Q13554	CAMK2B	S932	S935T	935	Missense	distal	3	no	160.671	161.762	EPSD	CCLE	127.946	Up-regulation
CAMK_CAMK2_CAMK2B_ST	Q13131	PRKAA1	Q13554	CAMK2B	S496	S494L	494	Missense	proximal	-2	no	151.709	155.175	EPSD	CCLE	127.946	Up-regulation
CAMK_CAMK2_CAMK2B_ST	Q13131	PRKAA1	Q13554	CAMK2B	S496	S494W	494	Missense	proximal	-2	no	151.709	146.253	EPSD	CCLE	127.946	Down-regulation
CAMK_CAMK2_CAMK2B_ST	Q16625	OCLN	Q13554	CAMK2B	S458	R459C	459	Missense	proximal	1	no	130.279	108.520	EPSD	CCLE	127.946	Loss
CAMK_CAMK2_CAMK2B_ST	Q13555	CAMK2G	Q13554	CAMK2B	S280	R284C	284	Missense	distal	4	no	132.658	130.965	EPSD	CCLE	127.946	Down-regulation
CAMK_CAMK2_CAMK2B_ST	Q13555	CAMK2G	Q13554	CAMK2B	T287	R284C	284	Missense	distal	-3	no	161.152	117.099	PhosphoSitePlus	CCLE	127.946	Loss
STE_STE20_PAKB_PAK5_ST	P15976	GATA1	Q9P286	PAK5	S107	P111L	111	Missense	distal	4	no	4.412	4.293	EPSD	CCLE	3.202	Down-regulation
STE_STE20_PAKB_PAK5_ST	P15923	TCF3	Q9P286	PAK5	S39	G42R	42	Missense	distal	3	no	8.243	8.249	PhosphoSitePlus	CCLE	3.202	Up-regulation
STE_STE20_PAKB_PAK5_ST	P15923	TCF3	Q9P286	PAK5	S39	A38V	38	Missense	proximal	-1	no	8.243	8.145	PhosphoSitePlus	CCLE	3.202	Down-regulation
STE_STE20_PAKB_PAK5_ST	P15923	TCF3	Q9P286	PAK5	S55	L50F	50	Missense	distal	-5	no	4.552	4.568	EPSD	CCLE	3.202	Up-regulation
STE_STE20_PAKB_PAK5_ST	P15923	TCF3	Q9P286	PAK5	S305	V304I	304	Missense	proximal	-1	no	3.193	3.309	EPSD	CCLE	3.202	Gain
STE_STE20_PAKB_PAK5_ST	P15923	TCF3	Q9P286	PAK5	S306	V304I	304	Missense	proximal	-2	no	4.206	4.273	EPSD	CCLE	3.202	Up-regulation
STE_STE20_PAKB_PAK5_ST	P15923	TCF3	Q9P286	PAK5	S338	S345L	345	Missense	distal	7	no	3.430	3.685	EPSD	CCLE	3.202	Up-regulation
STE_STE20_PAKB_PAK5_ST	P15923	TCF3	Q9P286	PAK5	S350	S345L	345	Missense	distal	-5	no	3.461	3.462	EPSD	CCLE	3.202	Up-regulation
STE_STE20_PAKB_PAK5_ST	P15923	TCF3	Q9P286	PAK5	S352	S345L	345	Missense	distal	-7	no	3.389	3.569	EPSD	CCLE	3.202	Up-regulation
STE_STE20_PAKB_PAK5_ST	P15923	TCF3	Q9P286	PAK5	S367	A374D	374	Missense	distal	7	no	3.908	3.833	EPSD	CCLE	3.202	Down-regulation
CAMK_CASK_CASK_ST	O14936	CASK	O14936	CASK	S151	H145N	145	Missense	distal	-6	no	7.373	7.315	PhosphoSitePlus;EPSD	CCLE	2.569	Down-regulation
STE_STE7_MEK3_MAP2K6_ST	P52564	MAP2K6	P52564	MAP2K6	S207	D213H	213	Missense	distal	6	no	8.152	8.153	PhosphoSitePlus;EPSD	CCLE	1.858	Up-regulation
STE_STE7_MEK3_MAP2K6_ST	Q16539	MAPK14	P52564	MAP2K6	T7	Q3E	3	Missense	distal	-4	no	3.567	3.581	EPSD	CCLE	1.858	Up-regulation
STE_STE7_MEK3_MAP2K6_ST	Q16539	MAPK14	P52564	MAP2K6	T7	N14K	14	Missense	distal	7	no	3.567	3.574	EPSD	CCLE	1.858	Up-regulation
TK_Csk_MATK_Y	P78324	SIRPA	P42679	MATK	Y429	N425H	425	Missense	distal	-4	no	5.372	4.224	EPSD;PhosphoSitePlus	CCLE	1.382	Down-regulation
TK_Csk_MATK_Y	P78324	SIRPA	P42679	MATK	Y429	P435H	435	Missense	distal	6	no	5.372	5.342	EPSD;PhosphoSitePlus	CCLE	1.382	Down-regulation
CK1_VRK_VRK2_ST	P38432	COIL	Q86Y07	VRK2	S217	Q214R	214	Missense	distal	-3	no	36.934	39.980	EPSD	CCLE	34.967	Up-regulation
CK1_VRK_VRK2_ST	P38432	COIL	Q86Y07	VRK2	S218	Q214R	214	Missense	distal	-4	no	45.794	47.010	EPSD	CCLE	34.967	Up-regulation
CK1_VRK_VRK2_ST	Q9UHP3	USP25	Q86Y07	VRK2	T680	D684A	684	Missense	distal	4	no	97.663	97.623	PhosphoSitePlus;EPSD	CCLE	34.967	Down-regulation
CK1_VRK_VRK2_ST	Q9UHP3	USP25	Q86Y07	VRK2	S725	T730I	730	Missense	distal	5	no	42.104	40.952	EPSD	CCLE	34.967	Down-regulation
CK1_VRK_VRK2_ST	Q9UHP3	USP25	Q86Y07	VRK2	T727	T730I	730	Missense	distal	3	no	101.630	101.198	EPSD;PhosphoSitePlus	CCLE	34.967	Down-regulation
CK1_VRK_VRK2_ST	Q96EV8	DTNBP1	Q86Y07	VRK2	S53	T58A	58	Missense	distal	5	no	44.147	43.241	EPSD	CCLE	34.967	Down-regulation
AGC_DMPK_ROCK_ROCK1_ST	Q14160	SCRIB	Q13464	ROCK1	S35	R36H	36	Missense	proximal	1	no	33.012	33.572	EPSD	CCLE	31.796	Up-regulation
AGC_DMPK_ROCK_ROCK1_ST	Q14160	SCRIB	Q13464	ROCK1	T883	I876V	876	Missense	distal	-7	no	32.465	32.377	EPSD	CCLE	31.796	Down-regulation
AGC_DMPK_ROCK_ROCK1_ST	Q14160	SCRIB	Q13464	ROCK1	S1378	D1384N	1384	Missense	distal	6	no	39.728	39.792	EPSD;PhosphoSitePlus	CCLE	31.796	Up-regulation
AGC_DMPK_ROCK_ROCK1_ST	Q14160	SCRIB	Q13464	ROCK1	S1566	D1568G	1568	Missense	proximal	2	no	30.755	32.886	EPSD	CCLE	31.796	Gain
AGC_DMPK_ROCK_ROCK1_ST	P19634	SLC9A1	Q13464	ROCK1	T685	N681T	681	Missense	distal	-4	no	32.153	32.031	EPSD	CCLE	31.796	Down-regulation
AGC_DMPK_ROCK_ROCK1_ST	Q9NRY4	ARHGAP35	Q13464	ROCK1	S1236	S1236A	1236	Missense	central	0	yes	40.710	0.000	EPSD;PhosphoSitePlus	CCLE	31.796	Loss
AGC_DMPK_ROCK_ROCK1_ST	Q9Y613	FHOD1	Q13464	ROCK1	S1131	R1128H	1128	Missense	distal	-3	no	37.343	22.732	EPSD;PhosphoSitePlus	CCLE	31.796	Loss
AGC_DMPK_ROCK_ROCK1_ST	Q8N264	ARHGAP24	Q13464	ROCK1	S415	P417R	417	Missense	proximal	2	no	29.787	31.920	EPSD;PhosphoSitePlus	CCLE	31.796	Gain
AGC_DMPK_ROCK_ROCK1_ST	Q8N264	ARHGAP24	Q13464	ROCK1	S530	D533Y	533	Missense	distal	3	no	36.043	36.102	EPSD	CCLE	31.796	Up-regulation
AGC_DMPK_ROCK_ROCK1_ST	P14136	GFAP	Q13464	ROCK1	S38	P33L	33	Missense	distal	-5	no	39.789	40.812	PhosphoSitePlus;EPSD	CCLE	31.796	Up-regulation
AGC_DMPK_ROCK_ROCK1_ST	P17661	DES	Q13464	ROCK1	S81	A85T	85	Missense	distal	4	no	34.041	34.077	EPSD	CCLE	31.796	Up-regulation
AGC_DMPK_ROCK_ROCK1_ST	Q16555	DPYSL2	Q13464	ROCK1	T555	P551L	551	Missense	distal	-4	no	36.149	36.715	PhosphoSitePlus	CCLE	31.796	Up-regulation
AGC_DMPK_ROCK_ROCK1_ST	P53671	LIMK2	Q13464	ROCK1	S318	S318F	318	Missense	central	0	yes	32.280	0.000	EPSD	CCLE	31.796	Loss
AGC_DMPK_ROCK_ROCK1_ST	P53671	LIMK2	Q13464	ROCK1	S318	Q324K	324	Missense	distal	6	no	32.280	31.570	EPSD	CCLE	31.796	Loss
AGC_DMPK_ROCK_ROCK1_ST	P53671	LIMK2	Q13464	ROCK1	T505	N509S	509	Missense	distal	4	no	56.361	56.991	PhosphoSitePlus	CCLE	31.796	Up-regulation
AGC_DMPK_ROCK_ROCK1_ST	O60237	PPP1R12B	Q13464	ROCK1	S839	G841R	841	Missense	proximal	2	no	34.284	34.931	EPSD	CCLE	31.796	Up-regulation
AGC_DMPK_ROCK_ROCK1_ST	O60237	PPP1R12B	Q13464	ROCK1	S855	R853Q	853	Missense	proximal	-2	no	33.364	20.194	EPSD	CCLE	31.796	Loss
AGC_DMPK_ROCK_ROCK1_ST	O43293	DAPK3	Q13464	ROCK1	T299	R294L	294	Missense	distal	-5	no	35.827	32.903	EPSD;PhosphoSitePlus	CCLE	31.796	Down-regulation
AGC_DMPK_ROCK_ROCK1_ST	O43293	DAPK3	Q13464	ROCK1	T300	R294L	294	Missense	distal	-6	no	33.498	27.604	EPSD	CCLE	31.796	Loss
AGC_DMPK_ROCK_ROCK1_ST	O43293	DAPK3	Q13464	ROCK1	S414	E417D	417	Missense	distal	3	no	32.611	32.643	EPSD	CCLE	31.796	Up-regulation
AGC_DMPK_ROCK_ROCK1_ST	O43293	DAPK3	Q13464	ROCK1	S414	R412C	412	Missense	proximal	-2	no	32.611	-0.247	EPSD	CCLE	31.796	Loss
AGC_DMPK_ROCK_ROCK1_ST	P08670	VIM	Q13464	ROCK1	T32	Y38H	38	Missense	distal	6	no	37.377	36.941	EPSD	CCLE	31.796	Down-regulation
AGC_DMPK_ROCK_ROCK1_ST	P08670	VIM	Q13464	ROCK1	S72	G76E	76	Missense	distal	4	no	36.246	34.787	PhosphoSitePlus	CCLE	31.796	Down-regulation
AGC_DMPK_ROCK_ROCK1_ST	Q05397	PTK2	Q13464	ROCK1	S29	R35Q	35	Missense	distal	6	no	31.380	32.497	EPSD	CCLE	31.796	Gain
AGC_DMPK_ROCK_ROCK1_ST	Q05397	PTK2	Q13464	ROCK1	S463	F468C	468	Missense	distal	5	no	32.060	31.799	EPSD	CCLE	31.796	Down-regulation
AGC_DMPK_ROCK_ROCK1_ST	O14974	PPP1R12A	Q13464	ROCK1	S525	D518E	518	Missense	distal	-7	no	35.425	35.449	EPSD	CCLE	31.796	Up-regulation
AGC_DMPK_ROCK_ROCK1_ST	Q9UPT6	MAPK8IP3	Q13464	ROCK1	S1191	E1196G	1196	Missense	distal	5	no	33.950	33.508	EPSD	CCLE	31.796	Down-regulation
AGC_PKG_PRKG2_ST	P29474	NOS3	Q13237	PRKG2	S114	P115S	115	Missense	proximal	1	no	57.772	58.602	EPSD	CCLE	42.682	Up-regulation
AGC_PKG_PRKG2_ST	P04626	ERBB2	Q13237	PRKG2	S1174	V1181I	1181	Missense	distal	7	no	52.567	52.225	EPSD	CCLE	42.682	Down-regulation
AGC_PKG_PRKG2_ST	P29350	PTPN6	Q13237	PRKG2	S32	S26R	26	Missense	distal	-6	no	62.940	60.775	EPSD	CCLE	42.682	Down-regulation
AGC_PKG_PRKG2_ST	P29350	PTPN6	Q13237	PRKG2	T540	P542L	542	Missense	proximal	2	no	44.587	44.800	EPSD	CCLE	42.682	Up-regulation
AGC_PKG_PRKG2_ST	P09619	PDGFRB	Q13237	PRKG2	S705	R709C	709	Missense	distal	4	no	53.834	52.366	EPSD	CCLE	42.682	Down-regulation
AGC_PKG_PRKG2_ST	P09619	PDGFRB	Q13237	PRKG2	S748	S748L	748	Missense	central	0	yes	46.193	0.000	EPSD	CCLE	42.682	Loss
AGC_PKG_PRKG2_ST	Q14847	LASP1	Q13237	PRKG2	S61	Y57H	57	Missense	distal	-4	no	45.490	46.687	EPSD	CCLE	42.682	Up-regulation
AGC_PKG_PRKG2_ST	Q14847	LASP1	Q13237	PRKG2	S61	S61P	61	Missense	central	0	yes	45.490	0.000	EPSD	CCLE	42.682	Loss
AGC_PKG_PRKG2_ST	Q14847	LASP1	Q13237	PRKG2	S82	E79K	79	Missense	distal	-3	no	22.317	43.142	EPSD	CCLE	42.682	Gain
AGC_PKG_PRKG2_ST	P08581	MET	Q13237	PRKG2	S758	F753C	753	Missense	distal	-5	no	44.324	44.355	EPSD	CCLE	42.682	Up-regulation
AGC_PKG_PRKG2_ST	P08581	MET	Q13237	PRKG2	T759	F753C	753	Missense	distal	-6	no	41.235	42.862	EPSD	CCLE	42.682	Gain
TK_Fer_FER_Y	P15311	EZR	P16591	FER	Y478	V477L	477	Missense	proximal	-1	no	0.203	0.202	PhosphoSitePlus;EPSD	CCLE	0.101	Down-regulation
TK_Fer_FER_Y	P40763	STAT3	P16591	FER	Y674	D676A	676	Missense	proximal	2	no	0.132	0.115	EPSD	CCLE	0.101	Down-regulation
TK_Fer_FER_Y	Q13480	GAB1	P16591	FER	Y627	D629E	629	Missense	proximal	2	no	0.170	0.169	PhosphoSitePlus	CCLE	0.101	Down-regulation
CMGC_CDK_CDK9_CDK9_ST	O00267	SUPT5H	P50750	CDK9	T166	E160D	160	Missense	distal	-6	no	2.234	2.135	EPSD	CCLE	1.932	Down-regulation
CMGC_CDK_CDK9_CDK9_ST	O00267	SUPT5H	P50750	CDK9	T806	G811A	811	Missense	distal	5	no	5.999	5.928	EPSD;PhosphoSitePlus	CCLE	1.932	Down-regulation
CMGC_CDK_CDK9_CDK9_ST	O00267	SUPT5H	P50750	CDK9	S812	G811A	811	Missense	proximal	-1	no	2.029	2.019	EPSD	CCLE	1.932	Down-regulation
CMGC_CDK_CDK9_CDK9_ST	O00267	SUPT5H	P50750	CDK9	T814	G811A	811	Missense	distal	-3	no	6.210	6.216	PhosphoSitePlus;EPSD	CCLE	1.932	Up-regulation
CMGC_CDK_CDK9_CDK9_ST	O00267	SUPT5H	P50750	CDK9	S847	G853E	853	Missense	distal	6	no	3.374	3.427	EPSD	CCLE	1.932	Up-regulation
CMGC_CDK_CDK9_CDK9_ST	O00267	SUPT5H	P50750	CDK9	S847	T854P	854	Missense	distal	7	no	3.374	3.218	EPSD	CCLE	1.932	Down-regulation
CMGC_CDK_CDK9_CDK9_ST	O00267	SUPT5H	P50750	CDK9	T854	G853E	853	Missense	proximal	-1	no	6.761	6.766	EPSD	CCLE	1.932	Up-regulation
CMGC_CDK_CDK9_CDK9_ST	O00267	SUPT5H	P50750	CDK9	T854	T854P	854	Missense	central	0	yes	6.761	0.000	EPSD	CCLE	1.932	Loss
CMGC_CDK_CDK9_CDK9_ST	O00267	SUPT5H	P50750	CDK9	T859	G853E	853	Missense	distal	-6	no	5.525	5.600	EPSD	CCLE	1.932	Up-regulation
CMGC_CDK_CDK9_CDK9_ST	O00267	SUPT5H	P50750	CDK9	T859	T854P	854	Missense	distal	-5	no	5.525	5.725	EPSD	CCLE	1.932	Up-regulation
CMGC_CDK_CDK9_CDK9_ST	O00267	SUPT5H	P50750	CDK9	S897	S891Y	891	Missense	distal	-6	no	4.658	4.303	EPSD	CCLE	1.932	Down-regulation
CMGC_CDK_CDK9_CDK9_ST	O00267	SUPT5H	P50750	CDK9	S917	Y921C	921	Missense	distal	4	no	4.585	4.566	EPSD	CCLE	1.932	Down-regulation
CMGC_CDK_CDK9_CDK9_ST	Q15797	SMAD1	P50750	CDK9	S206	P207S	207	Missense	proximal	1	no	6.575	2.841	EPSD;PhosphoSitePlus	CCLE	1.932	Down-regulation
CMGC_CDK_CDK9_CDK9_ST	Q15797	SMAD1	P50750	CDK9	S214	P207S	207	Missense	distal	-7	no	5.787	5.791	EPSD;PhosphoSitePlus	CCLE	1.932	Up-regulation
CMGC_CDK_CDK9_CDK9_ST	Q15797	SMAD1	P50750	CDK9	S214	S214I	214	Missense	central	0	yes	5.787	0.000	EPSD;PhosphoSitePlus	CCLE	1.932	Loss
CMGC_CDK_CDK9_CDK9_ST	Q15797	SMAD1	P50750	CDK9	S456	P460S	460	Missense	distal	4	no	5.636	5.729	EPSD	CCLE	1.932	Up-regulation
CMGC_CDK_CDK9_CDK9_ST	Q15797	SMAD1	P50750	CDK9	S462	P460S	460	Missense	proximal	-2	no	2.834	2.595	EPSD	CCLE	1.932	Down-regulation
CMGC_CDK_CDK9_CDK9_ST	P50750	CDK9	P50750	CDK9	S353	R358C	358	Missense	distal	5	no	2.921	2.776	EPSD;PhosphoSitePlus	CCLE	1.932	Down-regulation
CMGC_CDK_CDK9_CDK9_ST	P50750	CDK9	P50750	CDK9	T354	R358C	358	Missense	distal	4	no	3.986	3.945	EPSD;PhosphoSitePlus	CCLE	1.932	Down-regulation
CMGC_CDK_CDK9_CDK9_ST	P50750	CDK9	P50750	CDK9	S357	R358C	358	Missense	proximal	1	no	2.355	1.488	EPSD	CCLE	1.932	Loss
CMGC_CDK_CDK9_CDK9_ST	P50750	CDK9	P50750	CDK9	T362	R358C	358	Missense	distal	-4	no	2.325	2.274	EPSD;PhosphoSitePlus	CCLE	1.932	Down-regulation
CMGC_CDK_CDK9_CDK9_ST	P50750	CDK9	P50750	CDK9	T363	R358C	358	Missense	distal	-5	no	2.770	2.619	EPSD;PhosphoSitePlus	CCLE	1.932	Down-regulation
CMGC_CDK_CDK9_CDK9_ST	P84022	SMAD3	P50750	CDK9	T179	P177A	177	Missense	proximal	-2	no	5.191	4.490	EPSD;PhosphoSitePlus	CCLE	1.932	Down-regulation
CMGC_CDK_CDK9_CDK9_ST	P84022	SMAD3	P50750	CDK9	T179	P180L	180	Missense	proximal	1	no	5.191	-0.408	EPSD;PhosphoSitePlus	CCLE	1.932	Loss
CMGC_CDK_CDK9_CDK9_ST	P24928	POLR2A	P50750	CDK9	S27	E30K	30	Missense	distal	3	no	4.480	4.542	EPSD	CCLE	1.932	Up-regulation
CMGC_CDK_CDK9_CDK9_ST	P24928	POLR2A	P50750	CDK9	T1568	P1567L	1567	Missense	proximal	-1	no	5.440	5.402	EPSD	CCLE	1.932	Down-regulation
CMGC_CDK_CDK9_CDK9_ST	P24928	POLR2A	P50750	CDK9	S1571	P1567L	1567	Missense	distal	-4	no	5.570	5.436	EPSD	CCLE	1.932	Down-regulation
CMGC_CDK_CDK9_CDK9_ST	P24928	POLR2A	P50750	CDK9	S1574	P1567L	1567	Missense	distal	-7	no	6.846	6.913	EPSD	CCLE	1.932	Up-regulation
CMGC_CDK_CDK9_CDK9_ST	P24928	POLR2A	P50750	CDK9	S1616	S1616Y	1616	Missense	central	0	yes	4.310	0.000	EPSD;PhosphoSitePlus	CCLE	1.932	Loss
CMGC_CDK_CDK9_CDK9_ST	P24928	POLR2A	P50750	CDK9	T1618	S1616Y	1616	Missense	proximal	-2	no	2.563	2.151	EPSD;PhosphoSitePlus	CCLE	1.932	Down-regulation
CMGC_CDK_CDK9_CDK9_ST	P24928	POLR2A	P50750	CDK9	S1619	S1616Y	1616	Missense	distal	-3	no	4.556	4.638	EPSD;PhosphoSitePlus	CCLE	1.932	Up-regulation
CMGC_CDK_CDK9_CDK9_ST	P24928	POLR2A	P50750	CDK9	S1654	T1660P	1660	Missense	distal	6	no	4.324	4.656	EPSD	CCLE	1.932	Up-regulation
CMGC_CDK_CDK9_CDK9_ST	P24928	POLR2A	P50750	CDK9	S1661	T1660P	1660	Missense	proximal	-1	no	4.306	4.317	EPSD	CCLE	1.932	Up-regulation
CMGC_CDK_CDK9_CDK9_ST	P24928	POLR2A	P50750	CDK9	S1710	Y1713S	1713	Missense	distal	3	no	4.267	4.505	EPSD	CCLE	1.932	Up-regulation
CMGC_CDK_CDK9_CDK9_ST	P24928	POLR2A	P50750	CDK9	S1717	Y1713S	1713	Missense	distal	-4	no	4.299	4.440	EPSD	CCLE	1.932	Up-regulation
CMGC_CDK_CDK9_CDK9_ST	P24928	POLR2A	P50750	CDK9	S1766	Y1762H	1762	Missense	distal	-4	no	4.505	4.515	EPSD	CCLE	1.932	Up-regulation
CMGC_CDK_CDK9_CDK9_ST	P24928	POLR2A	P50750	CDK9	T1854	K1859R	1859	Missense	distal	5	no	4.083	4.050	EPSD	CCLE	1.932	Down-regulation
CMGC_CDK_CDK9_CDK9_ST	P24928	POLR2A	P50750	CDK9	T1856	K1859R	1859	Missense	distal	3	no	2.320	2.278	EPSD	CCLE	1.932	Down-regulation
CMGC_CDK_CDK9_CDK9_ST	P24928	POLR2A	P50750	CDK9	S1857	K1859R	1859	Missense	proximal	2	no	4.315	4.338	EPSD	CCLE	1.932	Up-regulation
CMGC_CDK_CDK9_CDK9_ST	P24928	POLR2A	P50750	CDK9	S1861	K1859R	1859	Missense	proximal	-2	no	3.999	3.944	EPSD	CCLE	1.932	Down-regulation
CMGC_CDK_CDK9_CDK9_ST	P24928	POLR2A	P50750	CDK9	T1863	K1859R	1859	Missense	distal	-4	no	2.535	2.524	EPSD	CCLE	1.932	Down-regulation
CMGC_CDK_CDK9_CDK9_ST	P24928	POLR2A	P50750	CDK9	S1864	K1859R	1859	Missense	distal	-5	no	4.218	4.180	EPSD	CCLE	1.932	Down-regulation
CMGC_CDK_CDK9_CDK9_ST	P24928	POLR2A	P50750	CDK9	S1889	T1894S	1894	Missense	distal	5	no	3.452	3.731	EPSD	CCLE	1.932	Up-regulation
CMGC_CDK_CDK9_CDK9_ST	P24928	POLR2A	P50750	CDK9	T1891	T1894S	1894	Missense	distal	3	no	1.833	2.013	EPSD	CCLE	1.932	Gain
CMGC_CDK_CDK9_CDK9_ST	P24928	POLR2A	P50750	CDK9	S1892	T1894S	1894	Missense	proximal	2	no	4.537	4.420	EPSD	CCLE	1.932	Down-regulation
CMGC_CDK_CDK9_CDK9_ST	P24928	POLR2A	P50750	CDK9	S1896	T1894S	1894	Missense	proximal	-2	no	3.763	4.016	EPSD	CCLE	1.932	Up-regulation
CMGC_CDK_CDK9_CDK9_ST	P24928	POLR2A	P50750	CDK9	T1898	T1894S	1894	Missense	distal	-4	no	2.177	2.272	EPSD	CCLE	1.932	Up-regulation
CMGC_CDK_CDK9_CDK9_ST	P24928	POLR2A	P50750	CDK9	T1898	P1904S	1904	Missense	distal	6	no	2.177	2.208	EPSD	CCLE	1.932	Up-regulation
CMGC_CDK_CDK9_CDK9_ST	P24928	POLR2A	P50750	CDK9	S1899	T1894S	1894	Missense	distal	-5	no	4.454	4.739	EPSD	CCLE	1.932	Up-regulation
CMGC_CDK_CDK9_CDK9_ST	P24928	POLR2A	P50750	CDK9	S1899	P1904S	1904	Missense	distal	5	no	4.454	4.574	EPSD	CCLE	1.932	Up-regulation
CMGC_CDK_CDK9_CDK9_ST	P24928	POLR2A	P50750	CDK9	T1903	P1904S	1904	Missense	proximal	1	no	3.703	-0.031	EPSD	CCLE	1.932	Loss
CMGC_CDK_CDK9_CDK9_ST	P24928	POLR2A	P50750	CDK9	T1905	P1904S	1904	Missense	proximal	-1	no	2.161	2.198	EPSD	CCLE	1.932	Up-regulation
CMGC_CDK_CDK9_CDK9_ST	P24928	POLR2A	P50750	CDK9	S1906	P1904S	1904	Missense	proximal	-2	no	4.351	4.112	EPSD	CCLE	1.932	Down-regulation
CMGC_CDK_CDK9_CDK9_ST	P24928	POLR2A	P50750	CDK9	S1910	P1904S	1904	Missense	distal	-6	no	3.898	3.766	EPSD	CCLE	1.932	Down-regulation
CMGC_CDK_CDK9_CDK9_ST	P24928	POLR2A	P50750	CDK9	S1910	P1914L	1914	Missense	distal	4	no	3.898	3.856	EPSD	CCLE	1.932	Down-regulation
CMGC_CDK_CDK9_CDK9_ST	P24928	POLR2A	P50750	CDK9	T1912	P1914L	1914	Missense	proximal	2	no	2.660	2.826	EPSD	CCLE	1.932	Up-regulation
CMGC_CDK_CDK9_CDK9_ST	P24928	POLR2A	P50750	CDK9	S1913	P1914L	1914	Missense	proximal	1	no	4.458	-1.141	EPSD	CCLE	1.932	Loss
CMGC_CDK_CDK9_CDK9_ST	P24928	POLR2A	P50750	CDK9	T1915	P1914L	1914	Missense	proximal	-1	no	2.055	2.017	EPSD	CCLE	1.932	Down-regulation
CMGC_CDK_CDK9_CDK9_ST	P24928	POLR2A	P50750	CDK9	S1917	P1914L	1914	Missense	distal	-3	no	4.197	4.281	EPSD	CCLE	1.932	Up-regulation
CMGC_CDK_CDK9_CDK9_ST	P24928	POLR2A	P50750	CDK9	T1919	P1914L	1914	Missense	distal	-5	no	2.788	2.409	EPSD	CCLE	1.932	Down-regulation
CMGC_CDK_CDK9_CDK9_ST	P24928	POLR2A	P50750	CDK9	S1920	P1914L	1914	Missense	distal	-6	no	4.157	3.567	EPSD	CCLE	1.932	Down-regulation
CMGC_CDK_CDK9_CDK9_ST	P24928	POLR2A	P50750	CDK9	S1934	S1941F	1941	Missense	distal	7	no	4.273	4.601	EPSD	CCLE	1.932	Up-regulation
CMGC_CDK_CDK9_CDK9_ST	P24928	POLR2A	P50750	CDK9	T1939	S1941F	1941	Missense	proximal	2	no	1.775	1.979	EPSD	CCLE	1.932	Gain
CMGC_CDK_CDK9_CDK9_ST	P24928	POLR2A	P50750	CDK9	S1941	S1941F	1941	Missense	central	0	yes	4.343	0.000	EPSD	CCLE	1.932	Loss
CMGC_CDK_CDK9_CDK9_ST	P24928	POLR2A	P50750	CDK9	S1941	S1944Y	1944	Missense	distal	3	no	4.343	4.105	EPSD	CCLE	1.932	Down-regulation
CMGC_CDK_CDK9_CDK9_ST	P24928	POLR2A	P50750	CDK9	T1943	S1941F	1941	Missense	proximal	-2	no	3.014	2.495	EPSD	CCLE	1.932	Down-regulation
CMGC_CDK_CDK9_CDK9_ST	P24928	POLR2A	P50750	CDK9	T1943	S1944Y	1944	Missense	proximal	1	no	3.014	2.235	EPSD	CCLE	1.932	Down-regulation
CMGC_CDK_CDK9_CDK9_ST	P24928	POLR2A	P50750	CDK9	S1944	S1941F	1941	Missense	distal	-3	no	5.921	6.012	EPSD	CCLE	1.932	Up-regulation
CMGC_CDK_CDK9_CDK9_ST	P24928	POLR2A	P50750	CDK9	S1944	S1944Y	1944	Missense	central	0	yes	5.921	0.000	EPSD	CCLE	1.932	Loss
CMGC_CDK_CDK9_CDK9_ST	P24928	POLR2A	P50750	CDK9	S1948	S1941F	1941	Missense	distal	-7	no	5.389	5.451	EPSD	CCLE	1.932	Up-regulation
CMGC_CDK_CDK9_CDK9_ST	P24928	POLR2A	P50750	CDK9	S1948	S1944Y	1944	Missense	distal	-4	no	5.389	5.248	EPSD	CCLE	1.932	Down-regulation
CMGC_CDK_CDK9_CDK9_ST	P24928	POLR2A	P50750	CDK9	S1948	P1952A	1952	Missense	distal	4	no	5.389	5.356	EPSD	CCLE	1.932	Down-regulation
CMGC_CDK_CDK9_CDK9_ST	P24928	POLR2A	P50750	CDK9	T1950	S1944Y	1944	Missense	distal	-6	no	3.732	3.377	EPSD	CCLE	1.932	Down-regulation
CMGC_CDK_CDK9_CDK9_ST	P24928	POLR2A	P50750	CDK9	T1950	P1952A	1952	Missense	proximal	2	no	3.732	3.887	EPSD	CCLE	1.932	Up-regulation
CMGC_CDK_CDK9_CDK9_ST	P24928	POLR2A	P50750	CDK9	S1951	S1944Y	1944	Missense	distal	-7	no	6.457	6.512	EPSD	CCLE	1.932	Up-regulation
CMGC_CDK_CDK9_CDK9_ST	P24928	POLR2A	P50750	CDK9	S1951	P1952A	1952	Missense	proximal	1	no	6.457	1.292	EPSD	CCLE	1.932	Loss
CMGC_CDK_CDK9_CDK9_ST	P24928	POLR2A	P50750	CDK9	T1953	P1952A	1952	Missense	proximal	-1	no	3.266	3.231	EPSD	CCLE	1.932	Down-regulation
CMGC_CDK_CDK9_CDK9_ST	P24928	POLR2A	P50750	CDK9	T1957	P1952A	1952	Missense	distal	-5	no	3.835	3.503	EPSD	CCLE	1.932	Down-regulation
CMGC_CDK_CDK9_CDK9_ST	P24928	POLR2A	P50750	CDK9	S1958	P1952A	1952	Missense	distal	-6	no	6.241	5.714	EPSD	CCLE	1.932	Down-regulation
CMGC_CDK_CDK9_CDK9_ST	Q6PGQ7	BORA	P50750	CDK9	S183	P184H	184	Missense	proximal	1	no	4.367	-0.207	EPSD	CCLE	1.932	Loss
CMGC_CDK_CDK9_CDK9_ST	Q6PGQ7	BORA	P50750	CDK9	T306	S308P	308	Missense	proximal	2	no	2.023	2.060	EPSD	CCLE	1.932	Up-regulation
CMGC_CDK_CDK9_CDK9_ST	Q6PGQ7	BORA	P50750	CDK9	S308	S308P	308	Missense	central	0	yes	2.550	0.000	EPSD	CCLE	1.932	Loss
CMGC_CDK_CDK9_CDK9_ST	Q9H0D6	XRN2	P50750	CDK9	T433	T439I	439	Missense	distal	6	no	4.174	3.943	EPSD	CCLE	1.932	Down-regulation
CMGC_CDK_CDK9_CDK9_ST	Q9H0D6	XRN2	P50750	CDK9	T439	T439I	439	Missense	central	0	yes	5.819	0.000	PhosphoSitePlus	CCLE	1.932	Loss
CMGC_CDK_CDK9_CDK9_ST	Q9H0D6	XRN2	P50750	CDK9	S471	N468S	468	Missense	distal	-3	no	4.531	4.490	EPSD	CCLE	1.932	Down-regulation
CMGC_CDK_CDK9_CDK9_ST	Q9H0D6	XRN2	P50750	CDK9	S471	N468K	468	Missense	distal	-3	no	4.531	4.548	EPSD	CCLE	1.932	Up-regulation
CMGC_CDK_CDK9_CDK9_ST	Q9H0D6	XRN2	P50750	CDK9	S475	N468S	468	Missense	distal	-7	no	5.832	5.806	EPSD	CCLE	1.932	Down-regulation
CMGC_CDK_CDK9_CDK9_ST	Q9H0D6	XRN2	P50750	CDK9	S475	N468K	468	Missense	distal	-7	no	5.832	5.843	EPSD	CCLE	1.932	Up-regulation
CMGC_CDK_CDK9_CDK9_ST	Q9H0D6	XRN2	P50750	CDK9	T478	S485C	485	Missense	distal	7	no	1.611	1.945	EPSD	CCLE	1.932	Gain
CMGC_CDK_CDK9_CDK9_ST	Q9H0D6	XRN2	P50750	CDK9	T481	S485C	485	Missense	distal	4	no	2.301	2.146	EPSD	CCLE	1.932	Down-regulation
CMGC_CDK_CDK9_CDK9_ST	Q9H0D6	XRN2	P50750	CDK9	S485	S485C	485	Missense	central	0	yes	4.367	0.000	EPSD	CCLE	1.932	Loss
CMGC_CDK_CDK9_CDK9_ST	Q9H0D6	XRN2	P50750	CDK9	S487	S485C	485	Missense	proximal	-2	no	6.247	5.722	EPSD	CCLE	1.932	Down-regulation
CMGC_CDK_CDK9_CDK9_ST	Q9H0D6	XRN2	P50750	CDK9	S790	K788T	788	Missense	proximal	-2	no	2.214	2.223	EPSD	CCLE	1.932	Up-regulation
CMGC_CDK_CDK9_CDK9_ST	Q9H0D6	XRN2	P50750	CDK9	S790	K788I	788	Missense	proximal	-2	no	2.214	1.993	EPSD	CCLE	1.932	Down-regulation
CMGC_CDK_CDK9_CDK9_ST	Q9H0D6	XRN2	P50750	CDK9	S861	L859F	859	Missense	proximal	-2	no	2.157	2.188	EPSD	CCLE	1.932	Up-regulation
CMGC_CDK_CDK9_CDK9_ST	Q9H0D6	XRN2	P50750	CDK9	S861	L859Y	859	Missense	proximal	-2	no	2.157	2.295	EPSD	CCLE	1.932	Up-regulation
CMGC_CDK_CDK9_CDK9_ST	Q9H0D6	XRN2	P50750	CDK9	S861	L859H	859	Missense	proximal	-2	no	2.157	2.317	EPSD	CCLE	1.932	Up-regulation
CMGC_CDK_CDK9_CDK9_ST	Q9H0D6	XRN2	P50750	CDK9	S861	M860T	860	Missense	proximal	-1	no	2.157	2.166	EPSD	CCLE	1.932	Up-regulation
CMGC_CDK_CDK9_CDK9_ST	P37231	PPARG	P50750	CDK9	S273	M280I	280	Missense	distal	7	no	4.027	4.074	EPSD	CCLE	1.932	Up-regulation
CMGC_CDK_CDK9_CDK9_ST	P10275	AR	P50750	CDK9	S96	Q98R	98	Missense	proximal	2	no	4.065	4.111	EPSD	CCLE	1.932	Up-regulation
CMGC_CDK_CDK9_CDK9_ST	Q15596	NCOA2	P50750	CDK9	S29	D24E	24	Missense	distal	-5	no	6.112	6.208	EPSD	CCLE	1.932	Up-regulation
CMGC_CDK_CDK9_CDK9_ST	Q15596	NCOA2	P50750	CDK9	S554	S550L	550	Missense	distal	-4	no	3.599	3.445	EPSD	CCLE	1.932	Down-regulation
CMGC_CDK_CDK9_CDK9_ST	Q15596	NCOA2	P50750	CDK9	S655	P654S	654	Missense	proximal	-1	no	4.793	4.830	EPSD	CCLE	1.932	Up-regulation
CMGC_CDK_CDK9_CDK9_ST	Q15596	NCOA2	P50750	CDK9	S659	P654S	654	Missense	distal	-5	no	2.087	2.172	EPSD	CCLE	1.932	Up-regulation
CMGC_CDK_CDK9_CDK9_ST	Q15596	NCOA2	P50750	CDK9	S726	E733V	733	Missense	distal	7	no	1.922	1.976	EPSD	CCLE	1.932	Gain
CMGC_CDK_CDK9_CDK9_ST	Q15596	NCOA2	P50750	CDK9	S736	E733V	733	Missense	distal	-3	no	5.598	5.616	EPSD	CCLE	1.932	Up-regulation
CMGC_CDK_CDK9_CDK9_ST	P06400	RB1	P50750	CDK9	T373	M379T	379	Missense	distal	6	no	4.052	4.198	EPSD	CCLE	1.932	Up-regulation
CMGC_CDK_CDK9_CDK9_ST	P06400	RB1	P50750	CDK9	S608	P609H	609	Missense	proximal	1	no	4.435	-0.140	EPSD	CCLE	1.932	Loss
CMGC_CDK_CDK9_CDK9_ST	P06400	RB1	P50750	CDK9	S612	P609H	609	Missense	distal	-3	no	4.420	4.486	EPSD	CCLE	1.932	Up-regulation
CMGC_CDK_CDK9_CDK9_ST	P04637	TP53	P50750	CDK9	S33	E28Q	28	Missense	distal	-5	no	5.662	5.842	EPSD;PhosphoSitePlus	CCLE	1.932	Up-regulation
CAMK_CAMKL_MELK_MELK_ST	Q14680	MELK	Q14680	MELK	T167	A173T	173	Missense	distal	6	no	235.306	236.326	EPSD;PhosphoSitePlus	CCLE	155.919	Up-regulation
CAMK_CAMKL_MELK_MELK_ST	Q14680	MELK	Q14680	MELK	S171	A173T	173	Missense	proximal	2	no	219.497	208.832	EPSD;PhosphoSitePlus	CCLE	155.919	Down-regulation
CAMK_CAMKL_MELK_MELK_ST	Q14680	MELK	Q14680	MELK	S253	K255T	255	Missense	proximal	2	no	226.646	231.028	EPSD;PhosphoSitePlus	CCLE	155.919	Up-regulation
CAMK_CAMKL_MELK_MELK_ST	Q14680	MELK	Q14680	MELK	T387	S391P	391	Missense	distal	4	no	211.694	208.983	EPSD;PhosphoSitePlus	CCLE	155.919	Down-regulation
CAMK_CAMKL_MELK_MELK_ST	Q14680	MELK	Q14680	MELK	S391	S391P	391	Missense	central	0	yes	225.428	0.000	EPSD;PhosphoSitePlus	CCLE	155.919	Loss
CAMK_CAMKL_MELK_MELK_ST	Q14680	MELK	Q14680	MELK	T398	S391P	391	Missense	distal	-7	no	290.214	282.906	EPSD;PhosphoSitePlus	CCLE	155.919	Down-regulation
CAMK_CAMKL_MELK_MELK_ST	Q14680	MELK	Q14680	MELK	S529	G533R	533	Missense	distal	4	no	223.112	225.071	EPSD;PhosphoSitePlus	CCLE	155.919	Up-regulation
CAMK_CAMKL_MELK_MELK_ST	Q14680	MELK	Q14680	MELK	T539	G533R	533	Missense	distal	-6	no	236.033	231.887	EPSD;PhosphoSitePlus	CCLE	155.919	Down-regulation
CAMK_CAMKL_MELK_MELK_ST	P30305	CDC25B	Q14680	MELK	S67	K71E	71	Missense	distal	4	no	156.366	156.621	EPSD	CCLE	155.919	Up-regulation
CAMK_CAMKL_MELK_MELK_ST	P30305	CDC25B	Q14680	MELK	S67	K71T	71	Missense	distal	4	no	156.366	158.886	EPSD	CCLE	155.919	Up-regulation
CAMK_CAMKL_MELK_MELK_ST	P30305	CDC25B	Q14680	MELK	T69	K71E	71	Missense	proximal	2	no	172.298	174.724	EPSD	CCLE	155.919	Up-regulation
CAMK_CAMKL_MELK_MELK_ST	P30305	CDC25B	Q14680	MELK	T69	K71T	71	Missense	proximal	2	no	172.298	176.681	EPSD	CCLE	155.919	Up-regulation
CAMK_CAMKL_MELK_MELK_ST	P30305	CDC25B	Q14680	MELK	S91	S95Y	95	Missense	distal	4	no	158.041	156.425	EPSD	CCLE	155.919	Down-regulation
CAMK_CAMKL_MELK_MELK_ST	P23588	EIF4B	Q14680	MELK	T18	G25R	25	Missense	distal	7	no	135.068	163.174	EPSD	CCLE	155.919	Gain
CAMK_CAMKL_MELK_MELK_ST	P23588	EIF4B	Q14680	MELK	S192	N189K	189	Missense	distal	-3	no	143.960	158.468	EPSD	CCLE	155.919	Gain
STE_STE7_MEK1_MAP2K1_ST	P17542	TAL1	Q02750	MAP2K1	S122	P124S	124	Missense	proximal	2	no	155.948	158.338	PhosphoSitePlus	CCLE	68.590	Up-regulation
STE_STE7_MEK1_MAP2K1_ST	P17542	TAL1	Q02750	MAP2K1	S122	G116S	116	Missense	distal	-6	no	155.948	155.608	PhosphoSitePlus	CCLE	68.590	Down-regulation
STE_STE7_MEK1_MAP2K1_ST	P05787	KRT8	Q02750	MAP2K1	T242	Q236P	236	Missense	distal	-6	no	88.826	89.002	EPSD	CCLE	68.590	Up-regulation
STE_STE7_MEK1_MAP2K1_ST	Q00613	HSF1	Q02750	MAP2K1	S237	P243L	243	Missense	distal	6	no	81.356	82.541	EPSD	CCLE	68.590	Up-regulation
STE_STE7_MEK1_MAP2K1_ST	Q00613	HSF1	Q02750	MAP2K1	S290	R287M	287	Missense	distal	-3	no	70.764	69.466	EPSD	CCLE	68.590	Down-regulation
STE_STE7_MEK1_MAP2K1_ST	Q00613	HSF1	Q02750	MAP2K1	S291	R287M	287	Missense	distal	-4	no	77.443	80.140	EPSD	CCLE	68.590	Up-regulation
STE_STE7_MEK1_MAP2K1_ST	Q00613	HSF1	Q02750	MAP2K1	S292	R287M	287	Missense	distal	-5	no	86.996	87.412	EPSD	CCLE	68.590	Up-regulation
STE_STE7_MEK1_MAP2K1_ST	Q00613	HSF1	Q02750	MAP2K1	S529	A523D	523	Missense	distal	-6	no	85.046	85.073	EPSD	CCLE	68.590	Up-regulation
STE_STE7_MEK1_MAP2K1_ST	P04049	RAF1	Q02750	MAP2K1	T268	P271H	271	Missense	distal	3	no	68.866	69.554	EPSD	CCLE	68.590	Up-regulation
CAMK_CAMKL_QIK_SIK2_ST	Q9H0K1	SIK2	Q9H0K1	SIK2	S486	N490S	490	Missense	distal	4	no	1.429	1.388	EPSD	CCLE	1.318	Down-regulation
CAMK_CAMKL_QIK_SIK2_ST	Q9BV73	CEP250	Q9H0K1	SIK2	S1774	G1767C	1767	Missense	distal	-7	no	1.308	1.323	EPSD	CCLE	1.318	Gain
CAMK_CAMKL_QIK_SIK2_ST	Q9UQL6	HDAC5	Q9H0K1	SIK2	S16	G9R	9	Missense	distal	-7	no	1.413	1.470	EPSD	CCLE	1.318	Up-regulation
CAMK_CAMKL_QIK_SIK2_ST	Q9UQL6	HDAC5	Q9H0K1	SIK2	S713	R710G	710	Missense	distal	-3	no	1.661	1.464	EPSD	CCLE	1.318	Down-regulation
CMGC_CDK_CDK4_CDK6_ST	P06400	RB1	Q00534	CDK6	T373	M379T	379	Missense	distal	6	no	83.353	83.401	EPSD	CCLE	54.510	Up-regulation
CMGC_CDK_CDK4_CDK6_ST	P06400	RB1	Q00534	CDK6	S608	P609H	609	Missense	proximal	1	no	84.906	-8.220	EPSD	CCLE	54.510	Loss
CMGC_CDK_CDK4_CDK6_ST	P06400	RB1	Q00534	CDK6	S612	P609H	609	Missense	distal	-3	no	86.965	87.185	EPSD;PhosphoSitePlus	CCLE	54.510	Up-regulation
CMGC_CDK_CDK4_CDK6_ST	Q08999	RBL2	Q00534	CDK6	S40	D33N	33	Missense	distal	-7	no	86.652	86.999	EPSD	CCLE	54.510	Up-regulation
CMGC_CDK_CDK4_CDK6_ST	Q08999	RBL2	Q00534	CDK6	S40	P43L	43	Missense	distal	3	no	86.652	84.477	EPSD	CCLE	54.510	Down-regulation
CMGC_CDK_CDK4_CDK6_ST	Q08999	RBL2	Q00534	CDK6	T42	P43L	43	Missense	proximal	1	no	84.864	-12.143	EPSD	CCLE	54.510	Loss
CMGC_CDK_CDK4_CDK6_ST	Q08999	RBL2	Q00534	CDK6	S639	I634L	634	Missense	distal	-5	no	84.083	84.148	EPSD	CCLE	54.510	Up-regulation
CMGC_CDK_CDK4_CDK6_ST	Q08999	RBL2	Q00534	CDK6	T661	T665A	665	Missense	distal	4	no	54.740	54.857	EPSD	CCLE	54.510	Up-regulation
CMGC_CDK_CDK4_CDK6_ST	Q08999	RBL2	Q00534	CDK6	S662	T665A	665	Missense	distal	3	no	83.908	83.085	EPSD	CCLE	54.510	Down-regulation
CMGC_CDK_CDK4_CDK6_ST	Q08999	RBL2	Q00534	CDK6	S671	T665A	665	Missense	distal	-6	no	57.064	57.123	EPSD	CCLE	54.510	Up-regulation
CMGC_CDK_CDK4_CDK6_ST	Q08999	RBL2	Q00534	CDK6	S672	T665A	665	Missense	distal	-7	no	87.984	87.412	EPSD;PhosphoSitePlus	CCLE	54.510	Down-regulation
CMGC_CDK_CDK4_CDK6_ST	Q08999	RBL2	Q00534	CDK6	S1080	F1077C	1077	Missense	distal	-3	no	85.244	85.230	EPSD	CCLE	54.510	Down-regulation
CMGC_CDK_CDK4_CDK6_ST	Q08050	FOXM1	Q00534	CDK6	S331	L334S	334	Missense	distal	3	no	83.521	86.030	EPSD	CCLE	54.510	Up-regulation
CMGC_CDK_CDK4_CDK6_ST	Q08050	FOXM1	Q00534	CDK6	S331	D328E	328	Missense	distal	-3	no	83.521	83.434	EPSD	CCLE	54.510	Down-regulation
CMGC_CDK_CDK4_CDK6_ST	Q08050	FOXM1	Q00534	CDK6	S489	S493Y	493	Missense	distal	4	no	89.135	89.278	EPSD;PhosphoSitePlus	CCLE	54.510	Up-regulation
CMGC_CDK_CDK4_CDK6_ST	Q08050	FOXM1	Q00534	CDK6	S508	K514N	514	Missense	distal	6	no	88.172	88.155	EPSD;PhosphoSitePlus	CCLE	54.510	Down-regulation
CMGC_CDK_CDK4_CDK6_ST	Q08050	FOXM1	Q00534	CDK6	T510	K514N	514	Missense	distal	4	no	86.373	86.441	PhosphoSitePlus;EPSD	CCLE	54.510	Up-regulation
CMGC_CDK_CDK4_CDK6_ST	Q01196	RUNX1	Q00534	CDK6	S67	N69K	69	Missense	proximal	2	no	83.394	83.373	EPSD	CCLE	54.510	Down-regulation
CMGC_CDK_CDK4_CDK6_ST	Q01196	RUNX1	Q00534	CDK6	S249	T243A	243	Missense	distal	-6	no	85.517	85.576	EPSD	CCLE	54.510	Up-regulation
CMGC_CDK_CDK4_CDK6_ST	Q01196	RUNX1	Q00534	CDK6	S276	G282D	282	Missense	distal	6	no	86.145	86.129	PhosphoSitePlus;EPSD	CCLE	54.510	Down-regulation
CMGC_CDK_CDK4_CDK6_ST	Q01196	RUNX1	Q00534	CDK6	T284	T285S	285	Missense	proximal	1	no	20.723	59.692	EPSD	CCLE	54.510	Gain
CMGC_CDK_CDK4_CDK6_ST	Q01196	RUNX1	Q00534	CDK6	T334	M341V	341	Missense	distal	7	no	57.023	57.114	EPSD	CCLE	54.510	Up-regulation
CMGC_CDK_CDK4_CDK6_ST	Q01196	RUNX1	Q00534	CDK6	S383	A384S	384	Missense	proximal	1	no	7.947	58.943	EPSD	CCLE	54.510	Gain
CMGC_CDK_CDK4_CDK6_ST	Q96KS0	EGLN2	Q00534	CDK6	S130	P129H	129	Missense	proximal	-1	no	85.564	85.481	PhosphoSitePlus	CCLE	54.510	Down-regulation
CMGC_CDK_CDK4_CDK6_ST	Q96KS0	EGLN2	Q00534	CDK6	S155	G148D	148	Missense	distal	-7	no	57.175	57.040	EPSD	CCLE	54.510	Down-regulation
CMGC_CDK_CDK4_CDK6_ST	P14618	PKM	Q00534	CDK6	T405	T412A	412	Missense	distal	7	no	56.058	55.941	EPSD	CCLE	54.510	Down-regulation
CMGC_CDK_CDK4_CDK6_ST	P21333	FLNA	Q00534	CDK6	S3	S3I	3	Missense	central	0	yes	55.674	0.000	EPSD	CCLE	54.510	Loss
CMGC_CDK_CDK4_CDK6_ST	P21333	FLNA	Q00534	CDK6	S468	V463M	463	Missense	distal	-5	no	84.390	84.439	EPSD	CCLE	54.510	Up-regulation
CMGC_CDK_CDK4_CDK6_ST	P21333	FLNA	Q00534	CDK6	S1084	Q1078R	1078	Missense	distal	-6	no	83.347	83.359	EPSD	CCLE	54.510	Up-regulation
CMGC_CDK_CDK4_CDK6_ST	P46527	CDKN1B	Q00534	CDK6	S10	S12I	12	Missense	proximal	2	no	83.673	83.729	PhosphoSitePlus;EPSD	CCLE	54.510	Up-regulation
CMGC_CDK_CDK8_CDK8_ST	Q15797	SMAD1	P49336	CDK8	S206	P207S	207	Missense	proximal	1	no	50.529	36.302	EPSD;PhosphoSitePlus	CCLE	26.151	Down-regulation
CMGC_CDK_CDK8_CDK8_ST	Q15797	SMAD1	P49336	CDK8	S214	P207S	207	Missense	distal	-7	no	48.601	48.673	EPSD;PhosphoSitePlus	CCLE	26.151	Up-regulation
CMGC_CDK_CDK8_CDK8_ST	Q15797	SMAD1	P49336	CDK8	S214	S214I	214	Missense	central	0	yes	48.601	0.000	EPSD;PhosphoSitePlus	CCLE	26.151	Loss
CMGC_CDK_CDK8_CDK8_ST	Q15797	SMAD1	P49336	CDK8	S456	P460S	460	Missense	distal	4	no	28.337	28.305	EPSD	CCLE	26.151	Down-regulation
CMGC_CDK_CDK8_CDK8_ST	P84022	SMAD3	P49336	CDK8	T179	P177A	177	Missense	proximal	-2	no	49.631	41.581	EPSD;PhosphoSitePlus	CCLE	26.151	Down-regulation
CMGC_CDK_CDK8_CDK8_ST	P84022	SMAD3	P49336	CDK8	T179	P180L	180	Missense	proximal	1	no	49.631	23.778	EPSD;PhosphoSitePlus	CCLE	26.151	Loss
CMGC_CDK_CDK8_CDK8_ST	Q01094	E2F1	P49336	CDK8	S307	G309R	309	Missense	proximal	2	no	31.092	29.386	EPSD	CCLE	26.151	Down-regulation
CMGC_CDK_CDK8_CDK8_ST	Q01094	E2F1	P49336	CDK8	T311	G309R	309	Missense	proximal	-2	no	21.155	32.833	EPSD	CCLE	26.151	Gain
CMGC_CDK_CDK8_CDK8_ST	Q01094	E2F1	P49336	CDK8	S375	R373S	373	Missense	proximal	-2	no	49.538	46.784	PhosphoSitePlus	CCLE	26.151	Down-regulation
CMGC_CDK_CDK8_CDK8_ST	Q01094	E2F1	P49336	CDK8	S403	L402F	402	Missense	proximal	-1	no	31.917	32.236	EPSD	CCLE	26.151	Up-regulation
TK_Fak_PTK2_Y	P12814	ACTN1	Q05397	PTK2	Y12	Y12H	12	Missense	central	0	yes	0.000	0.000	PhosphoSitePlus	CCLE	0.000	Loss
TK_Fak_PTK2_Y	O43561	LAT	Q05397	PTK2	Y70	Y70S	70	Missense	central	0	yes	0.000	0.000	EPSD	CCLE	0.000	Loss
TK_Fak_PTK2_Y	P07949	RET	Q05397	PTK2	Y952	Y952F	952	Missense	central	0	yes	0.000	0.000	EPSD	CCLE	0.000	Loss
TK_Fak_PTK2_Y	P56945	BCAR1	Q05397	PTK2	Y653	Y653H	653	Missense	central	0	yes	0.000	0.000	EPSD	CCLE	0.000	Loss
AGC_RSK_RSKp90_RPS6KA1_ST	O95071	UBR5	Q15418	RPS6KA1	S110	F113L	113	Missense	distal	3	no	1.728	1.798	EPSD	CCLE	1.787	Gain
AGC_RSK_RSKp90_RPS6KA1_ST	O95071	UBR5	Q15418	RPS6KA1	S115	F113L	113	Missense	proximal	-2	no	1.788	1.780	EPSD	CCLE	1.787	Loss
AGC_RSK_RSKp90_RPS6KA1_ST	O95071	UBR5	Q15418	RPS6KA1	S1733	A1738T	1738	Missense	distal	5	no	1.950	1.902	EPSD	CCLE	1.787	Down-regulation
AGC_RSK_RSKp90_RPS6KA1_ST	O95071	UBR5	Q15418	RPS6KA1	T1734	A1738T	1738	Missense	distal	4	no	1.862	1.879	EPSD	CCLE	1.787	Up-regulation
AGC_RSK_RSKp90_RPS6KA1_ST	Q13164	MAPK7	Q15418	RPS6KA1	S337	R335L	335	Missense	proximal	-2	no	1.768	1.838	EPSD	CCLE	1.787	Gain
AGC_RSK_RSKp90_RPS6KA1_ST	O60343	TBC1D4	Q15418	RPS6KA1	S292	R299W	299	Missense	distal	7	no	1.869	1.875	EPSD	CCLE	1.787	Up-regulation
AGC_RSK_RSKp90_RPS6KA1_ST	O60343	TBC1D4	Q15418	RPS6KA1	S631	T625M	625	Missense	distal	-6	no	2.054	1.374	EPSD	CCLE	1.787	Loss
AGC_RSK_RSKp90_RPS6KA1_ST	Q92934	BAD	Q15418	RPS6KA1	S34	S32L	32	Missense	proximal	-2	no	1.868	1.871	EPSD	CCLE	1.787	Up-regulation
AGC_RSK_RSKp90_RPS6KA1_ST	Q92934	BAD	Q15418	RPS6KA1	S75	H73Q	73	Missense	proximal	-2	no	3.978	3.965	PhosphoSitePlus	CCLE	1.787	Down-regulation
AGC_RSK_RSKp90_RPS6KA1_ST	Q92934	BAD	Q15418	RPS6KA1	S75	R70W	70	Missense	distal	-5	no	3.978	4.119	PhosphoSitePlus	CCLE	1.787	Up-regulation
AGC_RSK_RSKp90_RPS6KA1_ST	Q8IX03	WWC1	Q15418	RPS6KA1	S262	W260C	260	Missense	proximal	-2	no	1.847	1.863	EPSD	CCLE	1.787	Up-regulation
AGC_RSK_RSKp90_RPS6KA1_ST	Q8IX03	WWC1	Q15418	RPS6KA1	S262	S268G	268	Missense	distal	6	no	1.847	1.848	EPSD	CCLE	1.787	Up-regulation
AGC_RSK_RSKp90_RPS6KA1_ST	Q8N122	RPTOR	Q15418	RPS6KA1	T126	E129G	129	Missense	distal	3	no	2.082	2.100	EPSD	CCLE	1.787	Up-regulation
AGC_RSK_RSKp90_RPS6KA1_ST	Q2M1Z3	ARHGAP31	Q15418	RPS6KA1	S593	N600H	600	Missense	distal	7	no	2.003	1.835	EPSD	CCLE	1.787	Down-regulation
AGC_RSK_RSKp90_RPS6KA1_ST	Q9H6Z4	RANBP3	Q15418	RPS6KA1	S72	P65S	65	Missense	distal	-7	no	2.294	2.303	EPSD	CCLE	1.787	Up-regulation
AGC_RSK_RSKp90_RPS6KA1_ST	P30305	CDC25B	Q15418	RPS6KA1	S36	G31D	31	Missense	distal	-5	no	1.762	1.818	EPSD	CCLE	1.787	Gain
AGC_RSK_RSKp90_RPS6KA1_ST	P30305	CDC25B	Q15418	RPS6KA1	S36	G41W	41	Missense	distal	5	no	1.762	2.014	EPSD	CCLE	1.787	Gain
AGC_RSK_RSKp90_RPS6KA1_ST	P30305	CDC25B	Q15418	RPS6KA1	S67	K71E	71	Missense	distal	4	no	2.025	2.007	EPSD	CCLE	1.787	Down-regulation
AGC_RSK_RSKp90_RPS6KA1_ST	P30305	CDC25B	Q15418	RPS6KA1	S67	K71T	71	Missense	distal	4	no	2.025	2.019	EPSD	CCLE	1.787	Down-regulation
AGC_RSK_RSKp90_RPS6KA1_ST	P30305	CDC25B	Q15418	RPS6KA1	S91	S95Y	95	Missense	distal	4	no	2.641	2.642	EPSD	CCLE	1.787	Up-regulation
AGC_RSK_RSKp90_RPS6KA1_ST	P30305	CDC25B	Q15418	RPS6KA1	S313	M311L	311	Missense	proximal	-2	no	2.414	2.415	EPSD	CCLE	1.787	Up-regulation
AGC_RSK_RSKp90_RPS6KA1_ST	P30305	CDC25B	Q15418	RPS6KA1	S313	C315F	315	Missense	proximal	2	no	2.414	2.225	EPSD	CCLE	1.787	Down-regulation
AGC_RSK_RSKp90_RPS6KA1_ST	Q8TB45	DEPTOR	Q15418	RPS6KA1	T259	N255S	255	Missense	distal	-4	no	2.132	2.205	EPSD	CCLE	1.787	Up-regulation
AGC_RSK_RSKp90_RPS6KA1_ST	Q8TB45	DEPTOR	Q15418	RPS6KA1	S286	S293N	293	Missense	distal	7	no	1.716	1.806	EPSD;PhosphoSitePlus	CCLE	1.787	Gain
AGC_RSK_RSKp90_RPS6KA1_ST	P49815	TSC2	Q15418	RPS6KA1	S609	T603P	603	Missense	distal	-6	no	1.958	1.601	EPSD	CCLE	1.787	Loss
AGC_RSK_RSKp90_RPS6KA1_ST	P49815	TSC2	Q15418	RPS6KA1	S999	L995I	995	Missense	distal	-4	no	1.893	1.645	EPSD	CCLE	1.787	Loss
AGC_RSK_RSKp90_RPS6KA1_ST	P49815	TSC2	Q15418	RPS6KA1	S999	N1006S	1006	Missense	distal	7	no	1.893	1.803	EPSD	CCLE	1.787	Down-regulation
AGC_RSK_RSKp90_RPS6KA1_ST	P49815	TSC2	Q15418	RPS6KA1	S1364	I1357L	1357	Missense	distal	-7	no	2.532	2.556	EPSD	CCLE	1.787	Up-regulation
AGC_RSK_RSKp90_RPS6KA1_ST	P49815	TSC2	Q15418	RPS6KA1	S1364	V1363I	1363	Missense	proximal	-1	no	2.532	2.263	EPSD	CCLE	1.787	Down-regulation
AGC_RSK_RSKp90_RPS6KA1_ST	P49815	TSC2	Q15418	RPS6KA1	S1364	E1366K	1366	Missense	proximal	2	no	2.532	2.402	EPSD	CCLE	1.787	Down-regulation
AGC_RSK_RSKp90_RPS6KA1_ST	O00418	EEF2K	Q15418	RPS6KA1	S359	S359C	359	Missense	central	0	yes	2.297	0.000	EPSD	CCLE	1.787	Loss
AGC_RSK_RSKp90_RPS6KA1_ST	O00418	EEF2K	Q15418	RPS6KA1	T364	S359C	359	Missense	distal	-5	no	2.078	2.341	EPSD	CCLE	1.787	Up-regulation
AGC_RSK_RSKp90_RPS6KA1_ST	P67809	YBX1	Q15418	RPS6KA1	T25	D24Y	24	Missense	proximal	-1	no	2.426	2.457	EPSD	CCLE	1.787	Up-regulation
AGC_RSK_RSKp90_RPS6KA1_ST	P21333	FLNA	Q15418	RPS6KA1	T1558	S1563N	1563	Missense	distal	5	no	2.077	1.985	EPSD	CCLE	1.787	Down-regulation
AGC_RSK_RSKp90_RPS6KA1_ST	P21333	FLNA	Q15418	RPS6KA1	S2260	P2256T	2256	Missense	distal	-4	no	2.156	2.073	EPSD	CCLE	1.787	Down-regulation
AGC_RSK_RSKp90_RPS6KA1_ST	P78371	CCT2	Q15418	RPS6KA1	T406	C412S	412	Missense	distal	6	no	1.580	1.787	EPSD	CCLE	1.787	Gain
AGC_RSK_RSKp90_RPS6KA1_ST	Q07889	SOS1	Q15418	RPS6KA1	S1032	R1026K	1026	Missense	distal	-6	no	1.057	1.952	EPSD	CCLE	1.787	Gain
AGC_RSK_RSKp90_RPS6KA1_ST	P13796	LCP1	Q15418	RPS6KA1	S474	A471G	471	Missense	distal	-3	no	2.365	1.629	EPSD	CCLE	1.787	Loss
AGC_RSK_RSKp90_RPS6KA1_ST	O14727	APAF1	Q15418	RPS6KA1	S268	R265K	265	Missense	distal	-3	no	2.874	2.456	EPSD;PhosphoSitePlus	CCLE	1.787	Down-regulation
AGC_RSK_RSKp90_RPS6KA1_ST	O14727	APAF1	Q15418	RPS6KA1	S268	V273E	273	Missense	distal	5	no	2.874	2.752	EPSD;PhosphoSitePlus	CCLE	1.787	Down-regulation
AGC_RSK_RSKp90_RPS6KA1_ST	P53355	DAPK1	Q15418	RPS6KA1	S57	S52N	52	Missense	distal	-5	no	1.690	1.951	EPSD	CCLE	1.787	Gain
AGC_RSK_RSKp90_RPS6KA1_ST	P53355	DAPK1	Q15418	RPS6KA1	S326	F322Y	322	Missense	distal	-4	no	2.159	2.084	EPSD	CCLE	1.787	Down-regulation
AGC_RSK_RSKp90_RPS6KA1_ST	Q92882	OSTF1	Q15418	RPS6KA1	T195	V198D	198	Missense	distal	3	no	1.937	1.933	EPSD	CCLE	1.787	Down-regulation
AGC_RSK_RSKp90_RPS6KA1_ST	P60983	GMFB	Q15418	RPS6KA1	T27	I32L	32	Missense	distal	5	no	2.127	2.060	PhosphoSitePlus	CCLE	1.787	Down-regulation
AGC_RSK_RSKp90_RPS6KA1_ST	P29317	EPHA2	Q15418	RPS6KA1	T773	A770T	770	Missense	distal	-3	no	2.288	1.842	EPSD	CCLE	1.787	Down-regulation
AGC_RSK_RSKp90_RPS6KA1_ST	P23588	EIF4B	Q15418	RPS6KA1	S183	N189K	189	Missense	distal	6	no	2.232	2.044	EPSD	CCLE	1.787	Down-regulation
AGC_RSK_RSKp90_RPS6KA1_ST	P01100	FOS	Q15418	RPS6KA1	S281	S278Y	278	Missense	distal	-3	no	1.813	1.721	EPSD	CCLE	1.787	Loss
AGC_RSK_RSKp90_RPS6KA1_ST	Q96RK0	CIC	Q15418	RPS6KA1	S211	L217P	217	Missense	distal	6	no	1.826	1.834	EPSD	CCLE	1.787	Up-regulation
AGC_RSK_RSKp90_RPS6KA1_ST	Q96RK0	CIC	Q15418	RPS6KA1	S333	R340S	340	Missense	distal	7	no	2.187	2.079	EPSD	CCLE	1.787	Down-regulation
AGC_RSK_RSKp90_RPS6KA1_ST	Q96RK0	CIC	Q15418	RPS6KA1	S431	A429V	429	Missense	proximal	-2	no	2.264	2.322	EPSD	CCLE	1.787	Up-regulation
AGC_RSK_RSKp90_RPS6KA1_ST	Q96RK0	CIC	Q15418	RPS6KA1	S894	P887T	887	Missense	distal	-7	no	2.127	2.125	EPSD	CCLE	1.787	Down-regulation
AGC_RSK_RSKp90_RPS6KA1_ST	Q96RK0	CIC	Q15418	RPS6KA1	S894	P897T	897	Missense	distal	3	no	2.127	2.183	EPSD	CCLE	1.787	Up-regulation
TK_PDGFR_PDGFRA_Y	P16234	PDGFRA	P16234	PDGFRA	Y1018	P1021H	1021	Missense	distal	3	no	20.400	19.477	PhosphoSitePlus;EPSD	CCLE	8.840	Down-regulation
TK_PDGFR_PDGFRA_Y	P16234	PDGFRA	P16234	PDGFRA	Y1018	I1025F	1025	Missense	distal	7	no	20.400	20.315	PhosphoSitePlus;EPSD	CCLE	8.840	Down-regulation
TK_PDGFR_PDGFRA_Y	Q9P219	CCDC88C	P16234	PDGFRA	Y1395	P1399L	1399	Missense	distal	4	no	9.006	8.932	EPSD	CCLE	8.840	Down-regulation
AGC_GRK_BARK_GRK2_ST	P41143	OPRD1	P25098	GRK2	S344	R347H	347	Missense	distal	3	no	141.487	140.717	EPSD	CCLE	128.034	Down-regulation
AGC_GRK_BARK_GRK2_ST	P41143	OPRD1	P25098	GRK2	T361	P366L	366	Missense	distal	5	no	152.449	148.875	EPSD	CCLE	128.034	Down-regulation
AGC_GRK_BARK_GRK2_ST	P41143	OPRD1	P25098	GRK2	S363	P366L	366	Missense	distal	3	no	149.684	149.128	PhosphoSitePlus	CCLE	128.034	Down-regulation
AGC_GRK_BARK_GRK2_ST	Q14940	SLC9A5	P25098	GRK2	S741	P746T	746	Missense	distal	5	no	142.504	141.541	EPSD	CCLE	128.034	Down-regulation
AGC_GRK_BARK_GRK2_ST	P08172	CHRM2	P25098	GRK2	T271	V275L	275	Missense	distal	4	no	142.748	127.583	EPSD;PhosphoSitePlus	CCLE	128.034	Loss
AGC_GRK_BARK_GRK2_ST	P08172	CHRM2	P25098	GRK2	S282	V275L	275	Missense	distal	-7	no	152.972	154.852	EPSD;PhosphoSitePlus	CCLE	128.034	Up-regulation
AGC_GRK_BARK_GRK2_ST	P08172	CHRM2	P25098	GRK2	S286	A291V	291	Missense	distal	5	no	149.588	150.037	EPSD;PhosphoSitePlus	CCLE	128.034	Up-regulation
AGC_GRK_BARK_GRK2_ST	P08172	CHRM2	P25098	GRK2	T287	A291V	291	Missense	distal	4	no	162.650	167.211	EPSD;PhosphoSitePlus	CCLE	128.034	Up-regulation
AGC_GRK_BARK_GRK2_ST	P08172	CHRM2	P25098	GRK2	S288	A291V	291	Missense	distal	3	no	156.673	163.542	EPSD;PhosphoSitePlus	CCLE	128.034	Up-regulation
AGC_GRK_BARK_GRK2_ST	P08172	CHRM2	P25098	GRK2	S290	A291V	291	Missense	proximal	1	no	145.638	150.276	EPSD;PhosphoSitePlus	CCLE	128.034	Up-regulation
AGC_GRK_BARK_GRK2_ST	P08172	CHRM2	P25098	GRK2	S294	A291V	291	Missense	distal	-3	no	138.400	139.413	EPSD;PhosphoSitePlus	CCLE	128.034	Up-regulation
AGC_GRK_BARK_GRK2_ST	P35372	OPRM1	P25098	GRK2	T396	P398L	398	Missense	proximal	2	no	158.879	153.936	EPSD	CCLE	128.034	Down-regulation
AGC_GRK_BARK_GRK2_ST	P21731	TBXA2R	P25098	GRK2	S324	R326L	326	Missense	proximal	2	no	131.962	124.429	EPSD	CCLE	128.034	Loss
AGC_GRK_BARK_GRK2_ST	P21731	TBXA2R	P25098	GRK2	S324	S324G	324	Missense	central	0	yes	131.962	0.000	EPSD	CCLE	128.034	Loss
AGC_GRK_BARK_GRK2_ST	P21731	TBXA2R	P25098	GRK2	S329	L336F	336	Missense	distal	7	no	136.048	135.555	EPSD	CCLE	128.034	Down-regulation
AGC_GRK_BARK_GRK2_ST	P21731	TBXA2R	P25098	GRK2	S329	R326L	326	Missense	distal	-3	no	136.048	127.998	EPSD	CCLE	128.034	Loss
AGC_GRK_BARK_GRK2_ST	P21731	TBXA2R	P25098	GRK2	S329	S324G	324	Missense	distal	-5	no	136.048	138.261	EPSD	CCLE	128.034	Up-regulation
AGC_GRK_BARK_GRK2_ST	P21731	TBXA2R	P25098	GRK2	S331	L336F	336	Missense	distal	5	no	159.561	159.815	EPSD	CCLE	128.034	Up-regulation
AGC_GRK_BARK_GRK2_ST	P21731	TBXA2R	P25098	GRK2	S331	R326L	326	Missense	distal	-5	no	159.561	145.463	EPSD	CCLE	128.034	Down-regulation
AGC_GRK_BARK_GRK2_ST	P21731	TBXA2R	P25098	GRK2	S331	S324G	324	Missense	distal	-7	no	159.561	162.823	EPSD	CCLE	128.034	Up-regulation
AGC_GRK_BARK_GRK2_ST	O95398	RAPGEF3	P25098	GRK2	S209	A202V	202	Missense	distal	-7	no	136.662	134.424	EPSD	CCLE	128.034	Down-regulation
AGC_GRK_BARK_GRK2_ST	O95398	RAPGEF3	P25098	GRK2	S915	R916C	916	Missense	proximal	1	no	141.113	134.896	EPSD	CCLE	128.034	Down-regulation
AGC_GRK_BARK_GRK2_ST	O95398	RAPGEF3	P25098	GRK2	S918	R916C	916	Missense	proximal	-2	no	129.954	122.417	EPSD	CCLE	128.034	Loss
AGC_GRK_BARK_GRK2_ST	P09497	CLTB	P25098	GRK2	S205	K210N	210	Missense	distal	5	no	173.206	171.149	PhosphoSitePlus	CCLE	128.034	Down-regulation
AGC_GRK_BARK_GRK2_ST	P09497	CLTB	P25098	GRK2	S213	K210N	210	Missense	distal	-3	no	156.722	171.668	EPSD	CCLE	128.034	Up-regulation
AGC_GRK_BARK_GRK2_ST	P09497	CLTB	P25098	GRK2	S217	K210N	210	Missense	distal	-7	no	161.415	160.589	EPSD	CCLE	128.034	Down-regulation
AGC_GRK_BARK_GRK2_ST	Q16539	MAPK14	P25098	GRK2	S28	R23C	23	Missense	distal	-5	no	132.395	124.975	EPSD	CCLE	128.034	Loss
AGC_GRK_BARK_GRK2_ST	P26038	MSN	P25098	GRK2	S384	K391E	391	Missense	distal	7	no	139.602	139.762	EPSD	CCLE	128.034	Up-regulation
AGC_GRK_BARK_GRK2_ST	P26038	MSN	P25098	GRK2	T567	R570G	570	Missense	distal	3	no	144.054	142.147	EPSD	CCLE	128.034	Down-regulation
AGC_GRK_BARK_GRK2_ST	P26038	MSN	P25098	GRK2	S576	R570G	570	Missense	distal	-6	no	157.522	156.188	EPSD	CCLE	128.034	Down-regulation
AGC_GRK_BARK_GRK2_ST	Q9Y2W7	KCNIP3	P25098	GRK2	S95	G99E	99	Missense	distal	4	no	135.418	137.987	PhosphoSitePlus	CCLE	128.034	Up-regulation
AGC_GRK_BARK_GRK2_ST	Q96A54	ADIPOR1	P25098	GRK2	T53	P57L	57	Missense	distal	4	no	143.691	132.877	EPSD;PhosphoSitePlus	CCLE	128.034	Down-regulation
AGC_GRK_BARK_GRK2_ST	Q15796	SMAD2	P25098	GRK2	S240	S233G	233	Missense	distal	-7	no	126.684	129.947	EPSD	CCLE	128.034	Gain
STE_STE11_MEKK2_MAP3K2_ST	P35222	CTNNB1	Q9Y2U5	MAP3K2	T201	T201P	201	Missense	central	0	yes	2.215	0.000	EPSD	CCLE	2.079	Loss
STE_STE11_MEKK2_MAP3K2_ST	P35222	CTNNB1	Q9Y2U5	MAP3K2	T201	D207G	207	Missense	distal	6	no	2.215	2.141	EPSD	CCLE	2.079	Down-regulation
STE_STE7_MEK1_MAP2K2_ST	P05787	KRT8	P36507	MAP2K2	S450	S451F	451	Missense	proximal	1	no	1.967	2.177	EPSD	CCLE	1.900	Up-regulation
TK_Jak_JAK3_Y	O95644	NFATC1	P52333	JAK3	Y268	N264S	264	Missense	distal	-4	no	81.913	82.931	EPSD	CCLE	65.077	Up-regulation
TK_Jak_JAK3_Y	O95644	NFATC1	P52333	JAK3	Y268	R273W	273	Missense	distal	5	no	81.913	83.845	EPSD	CCLE	65.077	Up-regulation
TK_Jak_JAK3_Y	P29353	SHC1	P52333	JAK3	Y520	S527R	527	Missense	distal	7	no	98.673	97.741	EPSD	CCLE	65.077	Down-regulation
TK_Jak_JAK3_Y	Q15717	ELAVL1	P52333	JAK3	Y200	A204V	204	Missense	distal	4	no	104.116	97.820	EPSD;PhosphoSitePlus	CCLE	65.077	Down-regulation
TK_Tec_ITK_Y	Q9H4E7	DEF6	Q08881	ITK	Y222	H228N	228	Missense	distal	6	no	19.489	19.426	PhosphoSitePlus;EPSD	CCLE	9.294	Down-regulation
TK_Tec_ITK_Y	Q13094	LCP2	Q08881	ITK	Y173	M172V	172	Missense	proximal	-1	no	18.517	18.627	PhosphoSitePlus	CCLE	9.294	Up-regulation
TK_Csk_CSK_Y	P06239	LCK	P41240	CSK	Y72	H76R	76	Missense	distal	4	no	43.094	42.870	EPSD	CCLE	33.668	Down-regulation
TK_Csk_CSK_Y	P07947	YES1	P41240	CSK	Y32	S26N	26	Missense	distal	-6	no	41.419	36.852	EPSD	CCLE	33.668	Down-regulation
CMGC_MAPK_ERK5_MAPK7_ST	Q13164	MAPK7	Q13164	MAPK7	S282	V285M	285	Missense	distal	3	no	91.233	91.047	EPSD	CCLE	81.800	Down-regulation
CMGC_MAPK_ERK5_MAPK7_ST	Q13164	MAPK7	Q13164	MAPK7	S472	I471V	471	Missense	proximal	-1	no	93.483	93.589	EPSD	CCLE	81.800	Up-regulation
CMGC_MAPK_ERK5_MAPK7_ST	Q02078	MEF2A	Q13164	MAPK7	S98	S98N	98	Missense	central	0	yes	86.031	0.000	EPSD	CCLE	81.800	Loss
CMGC_MAPK_ERK5_MAPK7_ST	Q02078	MEF2A	Q13164	MAPK7	S98	C96Y	96	Missense	proximal	-2	no	86.031	92.830	EPSD	CCLE	81.800	Up-regulation
CMGC_MAPK_ERK5_MAPK7_ST	Q12959	DLG1	Q13164	MAPK7	S86	T81S	81	Missense	distal	-5	no	89.177	88.870	EPSD	CCLE	81.800	Down-regulation
CMGC_MAPK_ERK5_MAPK7_ST	Q12959	DLG1	Q13164	MAPK7	S100	L101P	101	Missense	proximal	1	no	93.013	111.470	EPSD	CCLE	81.800	Up-regulation
CMGC_MAPK_ERK5_MAPK7_ST	Q12959	DLG1	Q13164	MAPK7	S102	L101P	101	Missense	proximal	-1	no	90.047	89.804	EPSD	CCLE	81.800	Down-regulation
CMGC_MAPK_ERK5_MAPK7_ST	Q12959	DLG1	Q13164	MAPK7	S443	V450G	450	Missense	distal	7	no	84.273	85.079	EPSD	CCLE	81.800	Up-regulation
CMGC_MAPK_ERK5_MAPK7_ST	Q12959	DLG1	Q13164	MAPK7	S448	V450G	450	Missense	proximal	2	no	97.159	99.128	EPSD	CCLE	81.800	Up-regulation
CMGC_MAPK_ERK5_MAPK7_ST	Q12959	DLG1	Q13164	MAPK7	S575	R582Q	582	Missense	distal	7	no	89.841	92.191	EPSD	CCLE	81.800	Up-regulation
CMGC_MAPK_ERK5_MAPK7_ST	Q12959	DLG1	Q13164	MAPK7	S579	R582Q	582	Missense	distal	3	no	88.990	91.572	EPSD	CCLE	81.800	Up-regulation
CMGC_MAPK_ERK5_MAPK7_ST	Q06413	MEF2C	Q13164	MAPK7	T80	N73K	73	Missense	distal	-7	no	89.534	89.701	EPSD	CCLE	81.800	Up-regulation
CMGC_MAPK_ERK5_MAPK7_ST	P29590	PML	Q13164	MAPK7	T592	E598K	598	Missense	distal	6	no	85.995	84.400	EPSD	CCLE	81.800	Down-regulation
CMGC_MAPK_ERK5_MAPK7_ST	O00141	SGK1	Q13164	MAPK7	S377	R383W	383	Missense	distal	6	no	85.464	87.331	EPSD	CCLE	81.800	Up-regulation
CMGC_MAPK_ERK5_MAPK7_ST	P14921	ETS1	Q13164	MAPK7	T38	M44T	44	Missense	distal	6	no	108.456	111.314	PhosphoSitePlus	CCLE	81.800	Up-regulation
CMGC_MAPK_ERK5_MAPK7_ST	P14921	ETS1	Q13164	MAPK7	T38	V34A	34	Missense	distal	-4	no	108.456	111.254	PhosphoSitePlus	CCLE	81.800	Up-regulation
CMGC_MAPK_ERK5_MAPK7_ST	P14921	ETS1	Q13164	MAPK7	S46	M44T	44	Missense	proximal	-2	no	88.802	89.454	EPSD	CCLE	81.800	Up-regulation
CMGC_DYRK_HIPK_HIPK2_ST	Q9P1Z0	ZBTB4	Q9H2X6	HIPK2	S90	S97A	97	Missense	distal	7	no	101.860	101.729	EPSD	CCLE	98.777	Down-regulation
CMGC_DYRK_HIPK_HIPK2_ST	Q9P1Z0	ZBTB4	Q9H2X6	HIPK2	S91	S97A	97	Missense	distal	6	no	100.976	101.009	EPSD	CCLE	98.777	Up-regulation
CMGC_DYRK_HIPK_HIPK2_ST	Q9P1Z0	ZBTB4	Q9H2X6	HIPK2	S92	S97A	97	Missense	distal	5	no	101.620	101.720	EPSD	CCLE	98.777	Up-regulation
CMGC_DYRK_HIPK_HIPK2_ST	Q9P1Z0	ZBTB4	Q9H2X6	HIPK2	S93	S97A	97	Missense	distal	4	no	99.614	98.613	EPSD	CCLE	98.777	Loss
CMGC_DYRK_HIPK_HIPK2_ST	Q9P1Z0	ZBTB4	Q9H2X6	HIPK2	S104	S97A	97	Missense	distal	-7	no	103.114	103.986	EPSD	CCLE	98.777	Up-regulation
CMGC_DYRK_HIPK_HIPK2_ST	Q01196	RUNX1	Q9H2X6	HIPK2	S249	T243A	243	Missense	distal	-6	no	118.147	118.280	PhosphoSitePlus;EPSD	CCLE	98.777	Up-regulation
CMGC_DYRK_HIPK_HIPK2_ST	Q01196	RUNX1	Q9H2X6	HIPK2	S276	G282D	282	Missense	distal	6	no	119.422	119.478	EPSD;PhosphoSitePlus	CCLE	98.777	Up-regulation
CMGC_DYRK_HIPK_HIPK2_ST	Q01196	RUNX1	Q9H2X6	HIPK2	S281	T285S	285	Missense	distal	4	no	103.758	105.515	EPSD	CCLE	98.777	Up-regulation
CMGC_DYRK_HIPK_HIPK2_ST	Q01196	RUNX1	Q9H2X6	HIPK2	S281	G282D	282	Missense	proximal	1	no	103.758	87.331	EPSD	CCLE	98.777	Loss
CMGC_DYRK_HIPK_HIPK2_ST	Q01196	RUNX1	Q9H2X6	HIPK2	S292	T285S	285	Missense	distal	-7	no	99.133	99.789	EPSD	CCLE	98.777	Up-regulation
CMGC_DYRK_HIPK_HIPK2_ST	P57682	KLF3	Q9H2X6	HIPK2	S101	P103R	103	Missense	proximal	2	no	121.389	118.861	EPSD;PhosphoSitePlus	CCLE	98.777	Down-regulation
CMGC_DYRK_HIPK_HIPK2_ST	P57682	KLF3	Q9H2X6	HIPK2	S108	P103R	103	Missense	distal	-5	no	116.929	115.146	EPSD;PhosphoSitePlus	CCLE	98.777	Down-regulation
CMGC_DYRK_HIPK_HIPK2_ST	P57682	KLF3	Q9H2X6	HIPK2	S250	S250V	250	Missense	central	0	yes	119.124	0.000	EPSD;PhosphoSitePlus	CCLE	98.777	Loss
CMGC_DYRK_HIPK_HIPK2_ST	Q04724	TLE1	Q9H2X6	HIPK2	S235	H236P	236	Missense	proximal	1	no	3.983	116.037	EPSD	CCLE	98.777	Gain
CMGC_DYRK_HIPK_HIPK2_ST	Q04724	TLE1	Q9H2X6	HIPK2	S519	N517S	517	Missense	proximal	-2	no	98.703	98.961	EPSD	CCLE	98.777	Gain
CMGC_DYRK_HIPK_HIPK2_ST	P17096	HMGA1	Q9H2X6	HIPK2	T72	A69D	69	Missense	distal	-3	no	106.663	106.676	EPSD	CCLE	98.777	Up-regulation
CMGC_DYRK_HIPK_HIPK2_ST	P46531	NOTCH1	Q9H2X6	HIPK2	T1997	R1991C	1991	Missense	distal	-6	no	100.798	100.373	EPSD	CCLE	98.777	Down-regulation
CMGC_DYRK_HIPK_HIPK2_ST	P56545	CTBP2	Q9H2X6	HIPK2	S106	D112E	112	Missense	distal	6	no	100.528	101.012	EPSD	CCLE	98.777	Up-regulation
CMGC_DYRK_HIPK_HIPK2_ST	P56545	CTBP2	Q9H2X6	HIPK2	S106	I101N	101	Missense	distal	-5	no	100.528	96.814	EPSD	CCLE	98.777	Loss
CMGC_DYRK_HIPK_HIPK2_ST	P51608	MECP2	Q9H2X6	HIPK2	S178	P173A	173	Missense	distal	-5	no	113.419	104.575	EPSD	CCLE	98.777	Down-regulation
CMGC_DYRK_HIPK_HIPK2_ST	P51608	MECP2	Q9H2X6	HIPK2	S216	K223N	223	Missense	distal	7	no	117.624	117.522	PhosphoSitePlus;EPSD	CCLE	98.777	Down-regulation
CMGC_DYRK_HIPK_HIPK2_ST	P51608	MECP2	Q9H2X6	HIPK2	T228	G231E	231	Missense	distal	3	no	99.577	100.090	EPSD	CCLE	98.777	Up-regulation
CMGC_DYRK_HIPK_HIPK2_ST	P51608	MECP2	Q9H2X6	HIPK2	T228	K223N	223	Missense	distal	-5	no	99.577	95.748	EPSD	CCLE	98.777	Loss
CMGC_DYRK_HIPK_HIPK2_ST	P51608	MECP2	Q9H2X6	HIPK2	S229	G231E	231	Missense	proximal	2	no	105.967	107.344	EPSD	CCLE	98.777	Up-regulation
CMGC_DYRK_HIPK_HIPK2_ST	P51608	MECP2	Q9H2X6	HIPK2	S229	K223N	223	Missense	distal	-6	no	105.967	105.788	EPSD	CCLE	98.777	Down-regulation
CMGC_DYRK_HIPK_HIPK2_ST	P51608	MECP2	Q9H2X6	HIPK2	S291	V296M	296	Missense	distal	5	no	99.251	99.250	EPSD	CCLE	98.777	Down-regulation
CMGC_DYRK_HIPK_HIPK2_ST	P51608	MECP2	Q9H2X6	HIPK2	S332	G329S	329	Missense	distal	-3	no	99.281	99.193	EPSD	CCLE	98.777	Down-regulation
CMGC_DYRK_HIPK_HIPK2_ST	P51608	MECP2	Q9H2X6	HIPK2	S350	R344W	344	Missense	distal	-6	no	107.752	107.292	EPSD	CCLE	98.777	Down-regulation
CMGC_DYRK_HIPK_HIPK2_ST	P51608	MECP2	Q9H2X6	HIPK2	S409	S410R	410	Missense	proximal	1	no	96.872	101.615	EPSD	CCLE	98.777	Gain
CMGC_DYRK_HIPK_HIPK2_ST	P51608	MECP2	Q9H2X6	HIPK2	S410	S410R	410	Missense	central	0	yes	101.580	0.000	EPSD	CCLE	98.777	Loss
CMGC_DYRK_HIPK_HIPK2_ST	P51608	MECP2	Q9H2X6	HIPK2	S410	S409N	409	Missense	proximal	-1	no	101.580	100.532	EPSD	CCLE	98.777	Down-regulation
CMGC_DYRK_HIPK_HIPK2_ST	P04637	TP53	Q9H2X6	HIPK2	S33	E28Q	28	Missense	distal	-5	no	103.633	102.357	EPSD	CCLE	98.777	Down-regulation
CMGC_DYRK_HIPK_HIPK2_ST	O15297	PPM1D	Q9H2X6	HIPK2	S40	K38Q	38	Missense	proximal	-2	no	110.847	110.810	EPSD	CCLE	98.777	Down-regulation
CMGC_DYRK_HIPK_HIPK2_ST	O15297	PPM1D	Q9H2X6	HIPK2	S54	P48S	48	Missense	distal	-6	no	107.743	107.749	EPSD	CCLE	98.777	Up-regulation
CMGC_DYRK_HIPK_HIPK2_ST	O15297	PPM1D	Q9H2X6	HIPK2	S54	G60S	60	Missense	distal	6	no	107.743	107.972	EPSD	CCLE	98.777	Up-regulation
CMGC_DYRK_HIPK_HIPK2_ST	O15297	PPM1D	Q9H2X6	HIPK2	S64	G60S	60	Missense	distal	-4	no	104.842	104.924	EPSD	CCLE	98.777	Up-regulation
CMGC_DYRK_HIPK_HIPK2_ST	Q96EB6	SIRT1	Q9H2X6	HIPK2	S27	A29T	29	Missense	proximal	2	no	111.719	111.017	EPSD;PhosphoSitePlus	CCLE	98.777	Down-regulation
CMGC_DYRK_HIPK_HIPK2_ST	Q96EB6	SIRT1	Q9H2X6	HIPK2	S47	G52V	52	Missense	distal	5	no	111.144	111.182	EPSD	CCLE	98.777	Up-regulation
CMGC_DYRK_HIPK_HIPK2_ST	Q9H2X6	HIPK2	Q9H2X6	HIPK2	T566	N562Y	562	Missense	distal	-4	no	101.793	101.636	EPSD	CCLE	98.777	Down-regulation
CMGC_DYRK_HIPK_HIPK2_ST	P46527	CDKN1B	Q9H2X6	HIPK2	S10	S12I	12	Missense	proximal	2	no	103.610	102.428	PhosphoSitePlus	CCLE	98.777	Down-regulation
CMGC_DYRK_HIPK_HIPK2_ST	O00257	CBX4	Q9H2X6	HIPK2	S333	P340S	340	Missense	distal	7	no	103.909	103.949	EPSD	CCLE	98.777	Up-regulation
CMGC_DYRK_HIPK_HIPK2_ST	O00257	CBX4	Q9H2X6	HIPK2	S345	P340S	340	Missense	distal	-5	no	104.813	100.551	EPSD	CCLE	98.777	Down-regulation
CMGC_DYRK_HIPK_HIPK2_ST	O00257	CBX4	Q9H2X6	HIPK2	S442	R447C	447	Missense	distal	5	no	109.811	109.995	EPSD	CCLE	98.777	Up-regulation
CMGC_DYRK_HIPK_HIPK2_ST	O00257	CBX4	Q9H2X6	HIPK2	S442	A445S	445	Missense	distal	3	no	109.811	110.560	EPSD	CCLE	98.777	Up-regulation
CMGC_DYRK_HIPK_HIPK2_ST	O00257	CBX4	Q9H2X6	HIPK2	T497	V503A	503	Missense	distal	6	no	120.888	121.254	PhosphoSitePlus	CCLE	98.777	Up-regulation
CMGC_DYRK_HIPK_HIPK2_ST	O43255	SIAH2	Q9H2X6	HIPK2	T26	P19L	19	Missense	distal	-7	no	108.102	107.016	EPSD	CCLE	98.777	Down-regulation
CMGC_DYRK_HIPK_HIPK2_ST	P17676	CEBPB	Q9H2X6	HIPK2	S230	P236L	236	Missense	distal	6	no	101.352	100.979	EPSD	CCLE	98.777	Down-regulation
CMGC_DYRK_HIPK_HIPK2_ST	P17676	CEBPB	Q9H2X6	HIPK2	S231	P236L	236	Missense	distal	5	no	105.286	105.399	EPSD	CCLE	98.777	Up-regulation
CMGC_DYRK_HIPK_HIPK2_ST	P17676	CEBPB	Q9H2X6	HIPK2	S231	P238L	238	Missense	distal	7	no	105.286	105.108	EPSD	CCLE	98.777	Down-regulation
CMGC_DYRK_HIPK_HIPK2_ST	P17676	CEBPB	Q9H2X6	HIPK2	T235	P236L	236	Missense	proximal	1	no	117.638	-2.647	PhosphoSitePlus	CCLE	98.777	Loss
CMGC_DYRK_HIPK_HIPK2_ST	P17676	CEBPB	Q9H2X6	HIPK2	T235	P238L	238	Missense	distal	3	no	117.638	117.414	PhosphoSitePlus	CCLE	98.777	Down-regulation
CMGC_DYRK_HIPK_HIPK2_ST	P17676	CEBPB	Q9H2X6	HIPK2	S237	P236L	236	Missense	proximal	-1	no	107.804	106.414	EPSD	CCLE	98.777	Down-regulation
CMGC_DYRK_HIPK_HIPK2_ST	P17676	CEBPB	Q9H2X6	HIPK2	S237	P238L	238	Missense	proximal	1	no	107.804	-12.481	EPSD	CCLE	98.777	Loss
Atypical_PIKK_FRAP_MTOR_ST	Q13541	EIF4EBP1	P42345	MTOR	S65	P66H	66	Missense	proximal	1	no	9.149	-18.042	PhosphoSitePlus;EPSD	CCLE	6.822	Loss
Atypical_PIKK_FRAP_MTOR_ST	Q13541	EIF4EBP1	P42345	MTOR	T70	P66H	66	Missense	distal	-4	no	9.629	8.679	EPSD;PhosphoSitePlus	CCLE	6.822	Down-regulation
Atypical_PIKK_FRAP_MTOR_ST	Q13541	EIF4EBP1	P42345	MTOR	S101	R99C	99	Missense	proximal	-2	no	15.851	16.128	EPSD	CCLE	6.822	Up-regulation
Atypical_PIKK_FRAP_MTOR_ST	O75179	ANKRD17	P42345	MTOR	S19	V26G	26	Missense	distal	7	no	13.560	13.431	EPSD	CCLE	6.822	Down-regulation
Atypical_PIKK_FRAP_MTOR_ST	O75179	ANKRD17	P42345	MTOR	S47	R52H	52	Missense	distal	5	no	10.021	10.326	EPSD	CCLE	6.822	Up-regulation
Atypical_PIKK_FRAP_MTOR_ST	O75179	ANKRD17	P42345	MTOR	S47	R52S	52	Missense	distal	5	no	10.021	9.028	EPSD	CCLE	6.822	Down-regulation
Atypical_PIKK_FRAP_MTOR_ST	O75179	ANKRD17	P42345	MTOR	S49	R52H	52	Missense	distal	3	no	7.964	8.134	EPSD	CCLE	6.822	Up-regulation
Atypical_PIKK_FRAP_MTOR_ST	O75179	ANKRD17	P42345	MTOR	S49	R52S	52	Missense	distal	3	no	7.964	8.244	EPSD	CCLE	6.822	Up-regulation
Atypical_PIKK_FRAP_MTOR_ST	O75179	ANKRD17	P42345	MTOR	S50	R52H	52	Missense	proximal	2	no	12.246	11.868	EPSD	CCLE	6.822	Down-regulation
Atypical_PIKK_FRAP_MTOR_ST	O75179	ANKRD17	P42345	MTOR	S50	R52S	52	Missense	proximal	2	no	12.246	13.959	EPSD	CCLE	6.822	Up-regulation
Atypical_PIKK_FRAP_MTOR_ST	O75179	ANKRD17	P42345	MTOR	S469	A464T	464	Missense	distal	-5	no	9.636	9.616	EPSD	CCLE	6.822	Down-regulation
Atypical_PIKK_FRAP_MTOR_ST	O75179	ANKRD17	P42345	MTOR	S1220	A1226D	1226	Missense	distal	6	no	10.849	11.216	EPSD	CCLE	6.822	Up-regulation
Atypical_PIKK_FRAP_MTOR_ST	O75179	ANKRD17	P42345	MTOR	S1220	S1215R	1215	Missense	distal	-5	no	10.849	10.991	EPSD	CCLE	6.822	Up-regulation
Atypical_PIKK_FRAP_MTOR_ST	O75179	ANKRD17	P42345	MTOR	S1672	A1671G	1671	Missense	proximal	-1	no	7.344	7.342	EPSD	CCLE	6.822	Down-regulation
Atypical_PIKK_FRAP_MTOR_ST	O75179	ANKRD17	P42345	MTOR	S1734	V1740L	1740	Missense	distal	6	no	8.990	7.760	EPSD	CCLE	6.822	Down-regulation
Atypical_PIKK_FRAP_MTOR_ST	O75179	ANKRD17	P42345	MTOR	S2081	S2081R	2081	Missense	central	0	yes	8.988	0.000	EPSD	CCLE	6.822	Loss
Atypical_PIKK_FRAP_MTOR_ST	O75179	ANKRD17	P42345	MTOR	S2373	S2373Y	2373	Missense	central	0	yes	11.026	0.000	EPSD	CCLE	6.822	Loss
Atypical_PIKK_FRAP_MTOR_ST	O75179	ANKRD17	P42345	MTOR	S2401	R2398C	2398	Missense	distal	-3	no	11.495	10.783	EPSD	CCLE	6.822	Down-regulation
Atypical_PIKK_FRAP_MTOR_ST	O75179	ANKRD17	P42345	MTOR	T2509	R2502P	2502	Missense	distal	-7	no	9.021	9.343	EPSD	CCLE	6.822	Up-regulation
Atypical_PIKK_FRAP_MTOR_ST	Q9HB90	RRAGC	P42345	MTOR	S382	S384Y	384	Missense	proximal	2	no	7.160	5.423	EPSD	CCLE	6.822	Loss
Atypical_PIKK_FRAP_MTOR_ST	Q9HB90	RRAGC	P42345	MTOR	T394	G393D	393	Missense	proximal	-1	no	8.997	8.942	EPSD;PhosphoSitePlus	CCLE	6.822	Down-regulation
Atypical_PIKK_FRAP_MTOR_ST	Q9UQ35	SRRM2	P42345	MTOR	S172	K169E	169	Missense	distal	-3	no	8.383	8.378	EPSD	CCLE	6.822	Down-regulation
Atypical_PIKK_FRAP_MTOR_ST	Q9UQ35	SRRM2	P42345	MTOR	T252	A254V	254	Missense	proximal	2	no	10.245	10.993	EPSD	CCLE	6.822	Up-regulation
Atypical_PIKK_FRAP_MTOR_ST	Q9UQ35	SRRM2	P42345	MTOR	T252	R259Q	259	Missense	distal	7	no	10.245	9.846	EPSD	CCLE	6.822	Down-regulation
Atypical_PIKK_FRAP_MTOR_ST	Q9UQ35	SRRM2	P42345	MTOR	T367	P363S	363	Missense	distal	-4	no	9.152	9.281	EPSD	CCLE	6.822	Up-regulation
Atypical_PIKK_FRAP_MTOR_ST	Q9UQ35	SRRM2	P42345	MTOR	S398	P394L	394	Missense	distal	-4	no	8.860	8.674	EPSD	CCLE	6.822	Down-regulation
Atypical_PIKK_FRAP_MTOR_ST	Q9UQ35	SRRM2	P42345	MTOR	T476	R469W	469	Missense	distal	-7	no	8.522	8.982	EPSD	CCLE	6.822	Up-regulation
Atypical_PIKK_FRAP_MTOR_ST	Q9UQ35	SRRM2	P42345	MTOR	T476	H473R	473	Missense	distal	-3	no	8.522	9.269	EPSD	CCLE	6.822	Up-regulation
Atypical_PIKK_FRAP_MTOR_ST	Q9UQ35	SRRM2	P42345	MTOR	T476	H475D	475	Missense	proximal	-1	no	8.522	8.581	EPSD	CCLE	6.822	Up-regulation
Atypical_PIKK_FRAP_MTOR_ST	Q9UQ35	SRRM2	P42345	MTOR	S566	R570K	570	Missense	distal	4	no	11.868	12.171	EPSD	CCLE	6.822	Up-regulation
Atypical_PIKK_FRAP_MTOR_ST	Q9UQ35	SRRM2	P42345	MTOR	T577	R570K	570	Missense	distal	-7	no	7.518	7.663	EPSD	CCLE	6.822	Up-regulation
Atypical_PIKK_FRAP_MTOR_ST	Q9UQ35	SRRM2	P42345	MTOR	S629	R628Q	628	Missense	proximal	-1	no	10.965	10.984	EPSD	CCLE	6.822	Up-regulation
Atypical_PIKK_FRAP_MTOR_ST	Q9UQ35	SRRM2	P42345	MTOR	S629	S635P	635	Missense	distal	6	no	10.965	10.936	EPSD	CCLE	6.822	Down-regulation
Atypical_PIKK_FRAP_MTOR_ST	Q9UQ35	SRRM2	P42345	MTOR	S639	S635P	635	Missense	distal	-4	no	15.180	15.051	EPSD	CCLE	6.822	Down-regulation
Atypical_PIKK_FRAP_MTOR_ST	Q9UQ35	SRRM2	P42345	MTOR	S639	S644N	644	Missense	distal	5	no	15.180	16.661	EPSD	CCLE	6.822	Up-regulation
Atypical_PIKK_FRAP_MTOR_ST	Q9UQ35	SRRM2	P42345	MTOR	T866	E862Q	862	Missense	distal	-4	no	7.535	7.274	EPSD	CCLE	6.822	Down-regulation
Atypical_PIKK_FRAP_MTOR_ST	Q9UQ35	SRRM2	P42345	MTOR	T866	T866M	866	Missense	central	0	yes	7.535	0.000	EPSD	CCLE	6.822	Loss
Atypical_PIKK_FRAP_MTOR_ST	Q9UQ35	SRRM2	P42345	MTOR	S935	P936S	936	Missense	proximal	1	no	11.289	2.765	EPSD	CCLE	6.822	Loss
Atypical_PIKK_FRAP_MTOR_ST	Q9UQ35	SRRM2	P42345	MTOR	S937	P936S	936	Missense	proximal	-1	no	9.099	9.167	EPSD	CCLE	6.822	Up-regulation
Atypical_PIKK_FRAP_MTOR_ST	Q9UQ35	SRRM2	P42345	MTOR	S954	V959M	959	Missense	distal	5	no	10.223	8.968	EPSD	CCLE	6.822	Down-regulation
Atypical_PIKK_FRAP_MTOR_ST	Q9UQ35	SRRM2	P42345	MTOR	S1014	P1015S	1015	Missense	proximal	1	no	8.752	0.229	EPSD	CCLE	6.822	Loss
Atypical_PIKK_FRAP_MTOR_ST	Q9UQ35	SRRM2	P42345	MTOR	S1028	S1034F	1034	Missense	distal	6	no	7.441	6.866	EPSD	CCLE	6.822	Down-regulation
Atypical_PIKK_FRAP_MTOR_ST	Q9UQ35	SRRM2	P42345	MTOR	S1048	G1051A	1051	Missense	distal	3	no	7.414	7.401	EPSD	CCLE	6.822	Down-regulation
Atypical_PIKK_FRAP_MTOR_ST	Q9UQ35	SRRM2	P42345	MTOR	S1073	Q1078H	1078	Missense	distal	5	no	9.445	10.557	EPSD	CCLE	6.822	Up-regulation
Atypical_PIKK_FRAP_MTOR_ST	Q9UQ35	SRRM2	P42345	MTOR	S1144	D1141V	1141	Missense	distal	-3	no	9.835	9.846	EPSD	CCLE	6.822	Up-regulation
Atypical_PIKK_FRAP_MTOR_ST	Q9UQ35	SRRM2	P42345	MTOR	S1179	A1178T	1178	Missense	proximal	-1	no	7.467	7.419	EPSD	CCLE	6.822	Down-regulation
Atypical_PIKK_FRAP_MTOR_ST	Q9UQ35	SRRM2	P42345	MTOR	S1483	P1490S	1490	Missense	distal	7	no	7.968	7.947	EPSD	CCLE	6.822	Down-regulation
Atypical_PIKK_FRAP_MTOR_ST	Q9UQ35	SRRM2	P42345	MTOR	T1492	P1490S	1490	Missense	proximal	-2	no	7.770	7.414	EPSD	CCLE	6.822	Down-regulation
Atypical_PIKK_FRAP_MTOR_ST	Q9UQ35	SRRM2	P42345	MTOR	S1559	S1561Y	1561	Missense	proximal	2	no	6.938	5.201	EPSD	CCLE	6.822	Loss
Atypical_PIKK_FRAP_MTOR_ST	Q9UQ35	SRRM2	P42345	MTOR	S1648	K1643E	1643	Missense	distal	-5	no	14.914	14.622	EPSD	CCLE	6.822	Down-regulation
Atypical_PIKK_FRAP_MTOR_ST	Q9UQ35	SRRM2	P42345	MTOR	S1694	S1694F	1694	Missense	central	0	yes	11.187	0.000	EPSD	CCLE	6.822	Loss
Atypical_PIKK_FRAP_MTOR_ST	Q9UQ35	SRRM2	P42345	MTOR	S1727	P1728S	1728	Missense	proximal	1	no	10.374	1.850	EPSD	CCLE	6.822	Loss
Atypical_PIKK_FRAP_MTOR_ST	Q9UQ35	SRRM2	P42345	MTOR	S1732	P1728S	1728	Missense	distal	-4	no	10.028	10.157	EPSD	CCLE	6.822	Up-regulation
Atypical_PIKK_FRAP_MTOR_ST	Q9UQ35	SRRM2	P42345	MTOR	S1762	R1759T	1759	Missense	distal	-3	no	10.436	9.650	EPSD	CCLE	6.822	Down-regulation
Atypical_PIKK_FRAP_MTOR_ST	Q9UQ35	SRRM2	P42345	MTOR	S1764	R1759T	1759	Missense	distal	-5	no	10.855	10.720	EPSD	CCLE	6.822	Down-regulation
Atypical_PIKK_FRAP_MTOR_ST	Q9UQ35	SRRM2	P42345	MTOR	S1975	R1979H	1979	Missense	distal	4	no	9.092	8.832	EPSD	CCLE	6.822	Down-regulation
Atypical_PIKK_FRAP_MTOR_ST	Q9UQ35	SRRM2	P42345	MTOR	S1987	S1984F	1984	Missense	distal	-3	no	8.895	8.966	EPSD	CCLE	6.822	Up-regulation
Atypical_PIKK_FRAP_MTOR_ST	Q9UQ35	SRRM2	P42345	MTOR	S1999	R2003Q	2003	Missense	distal	4	no	9.503	9.635	EPSD	CCLE	6.822	Up-regulation
Atypical_PIKK_FRAP_MTOR_ST	Q9UQ35	SRRM2	P42345	MTOR	T2034	P2035Q	2035	Missense	proximal	1	no	8.206	-0.408	EPSD	CCLE	6.822	Loss
Atypical_PIKK_FRAP_MTOR_ST	Q9UQ35	SRRM2	P42345	MTOR	T2261	R2260Q	2260	Missense	proximal	-1	no	7.929	7.947	EPSD	CCLE	6.822	Up-regulation
Atypical_PIKK_FRAP_MTOR_ST	Q9UQ35	SRRM2	P42345	MTOR	T2329	P2333A	2333	Missense	distal	4	no	7.653	7.434	EPSD	CCLE	6.822	Down-regulation
Atypical_PIKK_FRAP_MTOR_ST	Q9UQ35	SRRM2	P42345	MTOR	S2650	S2646F	2646	Missense	distal	-4	no	10.432	10.457	EPSD	CCLE	6.822	Up-regulation
Atypical_PIKK_FRAP_MTOR_ST	Q9UQ35	SRRM2	P42345	MTOR	S2729	R2728C	2728	Missense	proximal	-1	no	9.377	9.550	EPSD	CCLE	6.822	Up-regulation
Atypical_PIKK_FRAP_MTOR_ST	Q9UQ35	SRRM2	P42345	MTOR	S2729	H2732Q	2732	Missense	distal	3	no	9.377	7.941	EPSD	CCLE	6.822	Down-regulation
Atypical_PIKK_FRAP_MTOR_ST	Q9UQ35	SRRM2	P42345	MTOR	T2738	H2732Q	2732	Missense	distal	-6	no	14.945	15.487	EPSD	CCLE	6.822	Up-regulation
Atypical_PIKK_FRAP_MTOR_ST	P42345	MTOR	P42345	MTOR	S1982	A1986T	1986	Missense	distal	4	no	6.733	7.275	EPSD	CCLE	6.822	Gain
Atypical_PIKK_FRAP_MTOR_ST	P42345	MTOR	P42345	MTOR	S2221	R2217W	2217	Missense	distal	-4	no	8.517	8.627	EPSD	CCLE	6.822	Up-regulation
Atypical_PIKK_FRAP_MTOR_ST	P55199	ELL	P42345	MTOR	S309	R316C	316	Missense	distal	7	no	16.235	16.665	PhosphoSitePlus	CCLE	6.822	Up-regulation
Atypical_PIKK_FRAP_MTOR_ST	P55199	ELL	P42345	MTOR	S309	R314L	314	Missense	distal	5	no	16.235	16.730	PhosphoSitePlus	CCLE	6.822	Up-regulation
Atypical_PIKK_FRAP_MTOR_ST	P55199	ELL	P42345	MTOR	S319	P320S	320	Missense	proximal	1	no	7.877	-0.647	EPSD	CCLE	6.822	Loss
Atypical_PIKK_FRAP_MTOR_ST	P55199	ELL	P42345	MTOR	S319	S319L	319	Missense	central	0	yes	7.877	0.000	EPSD	CCLE	6.822	Loss
Atypical_PIKK_FRAP_MTOR_ST	P55199	ELL	P42345	MTOR	S319	R316C	316	Missense	distal	-3	no	7.877	7.166	EPSD	CCLE	6.822	Down-regulation
Atypical_PIKK_FRAP_MTOR_ST	P55199	ELL	P42345	MTOR	S319	R314L	314	Missense	distal	-5	no	7.877	7.712	EPSD	CCLE	6.822	Down-regulation
Atypical_PIKK_FRAP_MTOR_ST	O75385	ULK1	P42345	MTOR	S405	G399S	399	Missense	distal	-6	no	7.192	7.071	EPSD	CCLE	6.822	Down-regulation
Atypical_PIKK_FRAP_MTOR_ST	O75385	ULK1	P42345	MTOR	S405	P406Q	406	Missense	proximal	1	no	7.192	-1.422	EPSD	CCLE	6.822	Loss
Atypical_PIKK_FRAP_MTOR_ST	O75385	ULK1	P42345	MTOR	S409	P406Q	406	Missense	distal	-3	no	6.979	7.149	EPSD	CCLE	6.822	Up-regulation
Atypical_PIKK_FRAP_MTOR_ST	O75385	ULK1	P42345	MTOR	S410	P406Q	406	Missense	distal	-4	no	7.123	6.869	EPSD	CCLE	6.822	Down-regulation
Atypical_PIKK_FRAP_MTOR_ST	O75385	ULK1	P42345	MTOR	S411	P406Q	406	Missense	distal	-5	no	9.285	9.294	EPSD	CCLE	6.822	Up-regulation
Atypical_PIKK_FRAP_MTOR_ST	O75385	ULK1	P42345	MTOR	S413	P406Q	406	Missense	distal	-7	no	12.999	12.599	EPSD	CCLE	6.822	Down-regulation
Atypical_PIKK_FRAP_MTOR_ST	O75385	ULK1	P42345	MTOR	T503	G499C	499	Missense	distal	-4	no	8.319	7.061	EPSD	CCLE	6.822	Down-regulation
Atypical_PIKK_FRAP_MTOR_ST	O75385	ULK1	P42345	MTOR	S623	L621M	621	Missense	proximal	-2	no	10.840	10.450	EPSD	CCLE	6.822	Down-regulation
Atypical_PIKK_FRAP_MTOR_ST	O75385	ULK1	P42345	MTOR	S623	G622V	622	Missense	proximal	-1	no	10.840	10.768	EPSD	CCLE	6.822	Down-regulation
Atypical_PIKK_FRAP_MTOR_ST	Q9H8M2	BRD9	P42345	MTOR	S571	E574G	574	Missense	distal	3	no	6.956	7.772	EPSD	CCLE	6.822	Up-regulation
Atypical_PIKK_FRAP_MTOR_ST	Q9H8M2	BRD9	P42345	MTOR	S588	P582S	582	Missense	distal	-6	no	19.616	19.596	PhosphoSitePlus	CCLE	6.822	Down-regulation
Atypical_PIKK_FRAP_MTOR_ST	Q8TB45	DEPTOR	P42345	MTOR	S260	N255S	255	Missense	distal	-5	no	7.170	7.260	EPSD	CCLE	6.822	Up-regulation
Atypical_PIKK_FRAP_MTOR_ST	Q8TB45	DEPTOR	P42345	MTOR	S286	S293N	293	Missense	distal	7	no	6.525	7.124	EPSD;PhosphoSitePlus	CCLE	6.822	Gain
Atypical_PIKK_FRAP_MTOR_ST	Q8TB45	DEPTOR	P42345	MTOR	S293	S292R	292	Missense	proximal	-1	no	8.165	8.004	EPSD;PhosphoSitePlus	CCLE	6.822	Down-regulation
Atypical_PIKK_FRAP_MTOR_ST	Q8TB45	DEPTOR	P42345	MTOR	S293	S293N	293	Missense	central	0	yes	8.165	0.000	EPSD;PhosphoSitePlus	CCLE	6.822	Loss
Atypical_PIKK_FRAP_MTOR_ST	Q8TB45	DEPTOR	P42345	MTOR	T295	S292R	292	Missense	distal	-3	no	9.860	10.205	PhosphoSitePlus;EPSD	CCLE	6.822	Up-regulation
Atypical_PIKK_FRAP_MTOR_ST	Q8TB45	DEPTOR	P42345	MTOR	T295	S293N	293	Missense	proximal	-2	no	9.860	9.269	PhosphoSitePlus;EPSD	CCLE	6.822	Down-regulation
Atypical_PIKK_FRAP_MTOR_ST	Q8TB45	DEPTOR	P42345	MTOR	S299	S292R	292	Missense	distal	-7	no	10.357	9.598	EPSD;PhosphoSitePlus	CCLE	6.822	Down-regulation
Atypical_PIKK_FRAP_MTOR_ST	Q8TB45	DEPTOR	P42345	MTOR	S299	S293N	293	Missense	distal	-6	no	10.357	9.670	EPSD;PhosphoSitePlus	CCLE	6.822	Down-regulation
Atypical_PIKK_FRAP_MTOR_ST	P23443	RPS6KB1	P42345	MTOR	S447	G454V	454	Missense	distal	7	no	9.793	9.921	EPSD	CCLE	6.822	Up-regulation
Atypical_PIKK_FRAP_MTOR_ST	P23443	RPS6KB1	P42345	MTOR	S452	G454V	454	Missense	proximal	2	no	7.565	7.728	EPSD	CCLE	6.822	Up-regulation
Atypical_PIKK_FRAP_MTOR_ST	P03372	ESR1	P42345	MTOR	S104	F97S	97	Missense	distal	-7	no	9.917	10.142	EPSD;PhosphoSitePlus	CCLE	6.822	Up-regulation
Atypical_PIKK_FRAP_MTOR_ST	P19484	TFEB	P42345	MTOR	S74	L70F	70	Missense	distal	-4	no	8.424	8.764	EPSD	CCLE	6.822	Up-regulation
Atypical_PIKK_FRAP_MTOR_ST	P19484	TFEB	P42345	MTOR	S195	P198A	198	Missense	distal	3	no	7.056	8.125	EPSD	CCLE	6.822	Up-regulation
Atypical_PIKK_FRAP_MTOR_ST	P19484	TFEB	P42345	MTOR	S211	S209N	209	Missense	proximal	-2	no	8.216	7.625	EPSD;PhosphoSitePlus	CCLE	6.822	Down-regulation
Atypical_PIKK_FRAP_MTOR_ST	P19484	TFEB	P42345	MTOR	S332	G335S	335	Missense	distal	3	no	8.896	7.828	EPSD	CCLE	6.822	Down-regulation
Atypical_PIKK_FRAP_MTOR_ST	Q9H4L4	SENP3	P42345	MTOR	S169	A162T	162	Missense	distal	-7	no	8.666	9.558	EPSD	CCLE	6.822	Up-regulation
Atypical_PIKK_FRAP_MTOR_ST	Q9H4L4	SENP3	P42345	MTOR	S212	P213S	213	Missense	proximal	1	no	7.513	-1.011	EPSD	CCLE	6.822	Loss
Atypical_PIKK_FRAP_MTOR_ST	Q8IYB3	SRRM1	P42345	MTOR	S380	R383W	383	Missense	distal	3	no	7.314	5.554	EPSD	CCLE	6.822	Loss
Atypical_PIKK_FRAP_MTOR_ST	Q8IYB3	SRRM1	P42345	MTOR	S389	R383W	383	Missense	distal	-6	no	11.652	12.025	EPSD	CCLE	6.822	Up-regulation
Atypical_PIKK_FRAP_MTOR_ST	Q8IYB3	SRRM1	P42345	MTOR	S501	K508E	508	Missense	distal	7	no	7.118	7.022	EPSD	CCLE	6.822	Down-regulation
Atypical_PIKK_FRAP_MTOR_ST	O95817	BAG3	P42345	MTOR	S264	P259L	259	Missense	distal	-5	no	10.328	10.256	EPSD	CCLE	6.822	Down-regulation
Atypical_PIKK_FRAP_MTOR_ST	O95817	BAG3	P42345	MTOR	S269	A273T	273	Missense	distal	4	no	7.798	8.340	EPSD	CCLE	6.822	Up-regulation
Atypical_PIKK_FRAP_MTOR_ST	O95817	BAG3	P42345	MTOR	S279	A273T	273	Missense	distal	-6	no	12.887	13.166	EPSD	CCLE	6.822	Up-regulation
Atypical_PIKK_FRAP_MTOR_ST	O95817	BAG3	P42345	MTOR	S279	E277V	277	Missense	proximal	-2	no	12.887	12.879	EPSD	CCLE	6.822	Down-regulation
Atypical_PIKK_FRAP_MTOR_ST	O95817	BAG3	P42345	MTOR	T285	S289P	289	Missense	distal	4	no	8.855	8.599	PhosphoSitePlus;EPSD	CCLE	6.822	Down-regulation
Atypical_PIKK_FRAP_MTOR_ST	O95817	BAG3	P42345	MTOR	S289	S289P	289	Missense	central	0	yes	14.805	0.000	EPSD;PhosphoSitePlus	CCLE	6.822	Loss
Atypical_PIKK_FRAP_MTOR_ST	O95817	BAG3	P42345	MTOR	S291	S289P	289	Missense	proximal	-2	no	11.061	11.417	EPSD	CCLE	6.822	Up-regulation
Atypical_PIKK_FRAP_MTOR_ST	O95817	BAG3	P42345	MTOR	T406	G411V	411	Missense	distal	5	no	9.329	9.789	EPSD	CCLE	6.822	Up-regulation
Atypical_PIKK_FRAP_MTOR_ST	O95817	BAG3	P42345	MTOR	S560	A558V	558	Missense	proximal	-2	no	7.205	6.726	EPSD	CCLE	6.822	Loss
Atypical_PIKK_FRAP_MTOR_ST	O95817	BAG3	P42345	MTOR	S564	A558V	558	Missense	distal	-6	no	12.763	12.478	EPSD	CCLE	6.822	Down-regulation
Atypical_PIKK_FRAP_MTOR_ST	Q9UPY5	SLC7A11	P42345	MTOR	S51	I58T	58	Missense	distal	7	no	7.824	6.503	EPSD	CCLE	6.822	Loss
Atypical_PIKK_FRAP_MTOR_ST	Q9UPY5	SLC7A11	P42345	MTOR	S51	T45A	45	Missense	distal	-6	no	7.824	7.545	EPSD	CCLE	6.822	Down-regulation
Atypical_PIKK_FRAP_MTOR_ST	Q86TB9	PATL1	P42345	MTOR	S278	P274S	274	Missense	distal	-4	no	10.419	10.548	EPSD	CCLE	6.822	Up-regulation
Atypical_PIKK_FRAP_MTOR_ST	Q13322	GRB10	P42345	MTOR	T155	L159F	159	Missense	distal	4	no	10.158	10.554	EPSD;PhosphoSitePlus	CCLE	6.822	Up-regulation
Atypical_PIKK_FRAP_MTOR_ST	O00141	SGK1	P42345	MTOR	S401	D403N	403	Missense	proximal	2	no	11.591	10.332	EPSD	CCLE	6.822	Down-regulation
Atypical_PIKK_FRAP_MTOR_ST	O96018	APBA3	P42345	MTOR	S9	P13H	13	Missense	distal	4	no	9.984	9.408	EPSD	CCLE	6.822	Down-regulation
Atypical_PIKK_FRAP_MTOR_ST	Q96F24	NRBF2	P42345	MTOR	S268	P262S	262	Missense	distal	-6	no	11.864	11.844	EPSD	CCLE	6.822	Down-regulation
Atypical_PIKK_FRAP_MTOR_ST	Q96F24	NRBF2	P42345	MTOR	S268	P267A	267	Missense	proximal	-1	no	11.864	11.926	EPSD	CCLE	6.822	Up-regulation
Atypical_PIKK_FRAP_MTOR_ST	Q8NHG8	ZNRF2	P42345	MTOR	S145	I143V	143	Missense	proximal	-2	no	9.832	10.354	PhosphoSitePlus	CCLE	6.822	Up-regulation
Atypical_PIKK_FRAP_MTOR_ST	Q9BRS8	LARP6	P42345	MTOR	S409	F413V	413	Missense	distal	4	no	8.698	8.629	PhosphoSitePlus;EPSD	CCLE	6.822	Down-regulation
Atypical_PIKK_FRAP_MTOR_ST	P26358	DNMT1	P42345	MTOR	T328	K335R	335	Missense	distal	7	no	7.485	8.631	EPSD	CCLE	6.822	Up-regulation
Atypical_PIKK_FRAP_MTOR_ST	P26358	DNMT1	P42345	MTOR	T328	T333M	333	Missense	distal	5	no	7.485	7.749	EPSD	CCLE	6.822	Up-regulation
Atypical_PIKK_FRAP_MTOR_ST	P26358	DNMT1	P42345	MTOR	S878	A874T	874	Missense	distal	-4	no	15.630	16.091	EPSD	CCLE	6.822	Up-regulation
Atypical_PIKK_FRAP_MTOR_ST	P26358	DNMT1	P42345	MTOR	S1105	P1099S	1099	Missense	distal	-6	no	15.842	15.822	EPSD	CCLE	6.822	Down-regulation
Atypical_PIKK_FRAP_MTOR_ST	P26358	DNMT1	P42345	MTOR	T1526	V1527I	1527	Missense	proximal	1	no	6.084	7.748	EPSD	CCLE	6.822	Gain
Atypical_PIKK_FRAP_MTOR_ST	P01106	MYC	P42345	MTOR	S62	P57H	57	Missense	distal	-5	no	13.333	13.431	PhosphoSitePlus	CCLE	6.822	Up-regulation
Atypical_PIKK_FRAP_MTOR_ST	P01106	MYC	P42345	MTOR	S62	L69I	69	Missense	distal	7	no	13.333	12.731	PhosphoSitePlus	CCLE	6.822	Down-regulation
Atypical_PIKK_FRAP_MTOR_ST	P01106	MYC	P42345	MTOR	S71	Y74S	74	Missense	distal	3	no	6.308	7.448	EPSD	CCLE	6.822	Gain
Atypical_PIKK_FRAP_MTOR_ST	P01106	MYC	P42345	MTOR	S71	T78R	78	Missense	distal	7	no	6.308	8.046	EPSD	CCLE	6.822	Gain
Atypical_PIKK_FRAP_MTOR_ST	P01106	MYC	P42345	MTOR	T78	Y74S	74	Missense	distal	-4	no	7.759	8.389	EPSD	CCLE	6.822	Up-regulation
Atypical_PIKK_FRAP_MTOR_ST	P01106	MYC	P42345	MTOR	T78	T78R	78	Missense	central	0	yes	7.759	0.000	EPSD	CCLE	6.822	Loss
Atypical_PIKK_FRAP_MTOR_ST	P01106	MYC	P42345	MTOR	T78	L82F	82	Missense	distal	4	no	7.759	8.155	EPSD	CCLE	6.822	Up-regulation
Atypical_PIKK_FRAP_MTOR_ST	P01106	MYC	P42345	MTOR	S81	T78R	78	Missense	distal	-3	no	6.353	7.138	EPSD	CCLE	6.822	Gain
Atypical_PIKK_FRAP_MTOR_ST	P01106	MYC	P42345	MTOR	S204	K206T	206	Missense	proximal	2	no	7.797	7.805	EPSD	CCLE	6.822	Up-regulation
Atypical_PIKK_FRAP_MTOR_ST	Q9C0C7	AMBRA1	P42345	MTOR	S722	A728V	728	Missense	distal	6	no	14.275	14.967	EPSD	CCLE	6.822	Up-regulation
Atypical_PIKK_FRAP_MTOR_ST	Q9C0C7	AMBRA1	P42345	MTOR	S1209	L1215F	1215	Missense	distal	6	no	7.017	7.631	EPSD	CCLE	6.822	Up-regulation
Atypical_PIKK_FRAP_MTOR_ST	Q00613	HSF1	P42345	MTOR	S244	P243L	243	Missense	proximal	-1	no	9.770	9.636	EPSD	CCLE	6.822	Down-regulation
Atypical_PIKK_FRAP_MTOR_ST	Q00613	HSF1	P42345	MTOR	S292	R287M	287	Missense	distal	-5	no	10.886	10.738	EPSD	CCLE	6.822	Down-regulation
Atypical_PIKK_FRAP_MTOR_ST	Q00613	HSF1	P42345	MTOR	T369	E371K	371	Missense	proximal	2	no	14.012	13.107	EPSD	CCLE	6.822	Down-regulation
Atypical_PIKK_FRAP_MTOR_ST	Q00613	HSF1	P42345	MTOR	S419	V424M	424	Missense	distal	5	no	14.113	12.858	EPSD	CCLE	6.822	Down-regulation
Atypical_PIKK_FRAP_MTOR_ST	Q00613	HSF1	P42345	MTOR	S518	A523D	523	Missense	distal	5	no	8.096	7.702	EPSD	CCLE	6.822	Down-regulation
Atypical_PIKK_FRAP_MTOR_ST	Q5T4S7	UBR4	P42345	MTOR	S4117	G4124W	4124	Missense	distal	7	no	11.895	11.917	EPSD	CCLE	6.822	Up-regulation
Atypical_PIKK_FRAP_MTOR_ST	Q5T4S7	UBR4	P42345	MTOR	S4513	Y4514D	4514	Missense	proximal	1	no	8.875	4.686	EPSD	CCLE	6.822	Loss
Atypical_PIKK_FRAP_MTOR_ST	Q5T4S7	UBR4	P42345	MTOR	S4513	F4512L	4512	Missense	proximal	-1	no	8.875	8.857	EPSD	CCLE	6.822	Down-regulation
Atypical_PIKK_FRAP_MTOR_ST	Q9H5H4	ZNF768	P42345	MTOR	S90	P95S	95	Missense	distal	5	no	9.700	9.586	EPSD	CCLE	6.822	Down-regulation
Atypical_PIKK_FRAP_MTOR_ST	Q9H5H4	ZNF768	P42345	MTOR	S97	P95S	95	Missense	proximal	-2	no	11.915	11.559	EPSD	CCLE	6.822	Down-regulation
Atypical_PIKK_FRAP_MTOR_ST	Q9H5H4	ZNF768	P42345	MTOR	S132	R138G	138	Missense	distal	6	no	9.467	11.219	EPSD	CCLE	6.822	Up-regulation
Atypical_PIKK_FRAP_MTOR_ST	Q9H5H4	ZNF768	P42345	MTOR	S139	E143D	143	Missense	distal	4	no	10.411	10.572	PhosphoSitePlus	CCLE	6.822	Up-regulation
Atypical_PIKK_FRAP_MTOR_ST	Q9H5H4	ZNF768	P42345	MTOR	S139	R138G	138	Missense	proximal	-1	no	10.411	10.566	PhosphoSitePlus	CCLE	6.822	Up-regulation
Atypical_PIKK_FRAP_MTOR_ST	Q9H5H4	ZNF768	P42345	MTOR	S160	P161L	161	Missense	proximal	1	no	11.449	5.480	EPSD	CCLE	6.822	Loss
Atypical_PIKK_FRAP_MTOR_ST	Q9H063	MAF1	P42345	MTOR	T245	A240V	240	Missense	distal	-5	no	13.162	13.073	EPSD	CCLE	6.822	Down-regulation
Atypical_PIKK_FRAP_MTOR_ST	Q9Y2J4	AMOTL2	P42345	MTOR	T106	E103G	103	Missense	distal	-3	no	6.274	7.020	EPSD	CCLE	6.822	Gain
Atypical_PIKK_FRAP_MTOR_ST	P04198	MYCN	P42345	MTOR	S377	D379E	379	Missense	proximal	2	no	7.775	8.756	EPSD	CCLE	6.822	Up-regulation
Atypical_PIKK_FRAP_MTOR_ST	Q9H4A3	WNK1	P42345	MTOR	S11	G4A	4	Missense	distal	-7	no	8.560	8.282	EPSD	CCLE	6.822	Down-regulation
Atypical_PIKK_FRAP_MTOR_ST	Q9H4A3	WNK1	P42345	MTOR	S1289	T1286I	1286	Missense	distal	-3	no	15.941	16.815	EPSD	CCLE	6.822	Up-regulation
Atypical_PIKK_FRAP_MTOR_ST	Q9H4A3	WNK1	P42345	MTOR	S1805	L1804V	1804	Missense	proximal	-1	no	10.006	10.129	EPSD	CCLE	6.822	Up-regulation
Other_NEK_NEK6_NEK6_ST	O95235	KIF20A	Q9HC98	NEK6	S240	V245I	245	Missense	distal	5	no	115.933	112.820	EPSD;PhosphoSitePlus	CCLE	73.015	Down-regulation
Other_NEK_NEK6_NEK6_ST	O95235	KIF20A	Q9HC98	NEK6	S244	V245I	245	Missense	proximal	1	no	113.449	114.676	EPSD;PhosphoSitePlus	CCLE	73.015	Up-regulation
Other_NEK_NEK6_NEK6_ST	O00141	SGK1	Q9HC98	NEK6	S61	P63L	63	Missense	proximal	2	no	84.877	82.087	EPSD	CCLE	73.015	Down-regulation
Other_NEK_NEK6_NEK6_ST	O00141	SGK1	Q9HC98	NEK6	S61	P63F	63	Missense	proximal	2	no	84.877	85.468	EPSD	CCLE	73.015	Up-regulation
Other_NEK_NEK6_NEK6_ST	O00141	SGK1	Q9HC98	NEK6	S377	R383W	383	Missense	distal	6	no	102.912	101.403	PhosphoSitePlus;EPSD	CCLE	73.015	Down-regulation
Other_NEK_NEK6_NEK6_ST	Q96AP0	ACD	Q9HC98	NEK6	S420	T422A	422	Missense	proximal	2	no	72.476	73.049	EPSD	CCLE	73.015	Gain
Other_NEK_NEK6_NEK6_ST	Q08999	RBL2	Q9HC98	NEK6	S40	D33N	33	Missense	distal	-7	no	75.408	75.060	EPSD	CCLE	73.015	Down-regulation
Other_NEK_NEK6_NEK6_ST	Q08999	RBL2	Q9HC98	NEK6	S40	P43L	43	Missense	distal	3	no	75.408	75.390	EPSD	CCLE	73.015	Down-regulation
Other_NEK_NEK6_NEK6_ST	Q08999	RBL2	Q9HC98	NEK6	S659	T665A	665	Missense	distal	6	no	114.357	114.421	PhosphoSitePlus	CCLE	73.015	Up-regulation
Other_NEK_NEK6_NEK6_ST	Q08999	RBL2	Q9HC98	NEK6	S1080	F1077C	1077	Missense	distal	-3	no	78.289	38.061	EPSD	CCLE	73.015	Loss
Other_NEK_NEK6_NEK6_ST	P52948	NUP98	Q9HC98	NEK6	S243	G249A	249	Missense	distal	6	no	88.975	90.001	EPSD	CCLE	73.015	Up-regulation
Other_NEK_NEK6_NEK6_ST	P52948	NUP98	Q9HC98	NEK6	S244	A251S	251	Missense	distal	7	no	77.772	77.553	EPSD	CCLE	73.015	Down-regulation
Other_NEK_NEK6_NEK6_ST	P52948	NUP98	Q9HC98	NEK6	S244	G249A	249	Missense	distal	5	no	77.772	79.499	EPSD	CCLE	73.015	Up-regulation
Other_NEK_NEK6_NEK6_ST	P50613	CDK7	Q9HC98	NEK6	S112	M118R	118	Missense	distal	6	no	87.819	88.276	EPSD	CCLE	73.015	Up-regulation
Other_NEK_NEK6_NEK6_ST	Q05586	GRIN1	Q9HC98	NEK6	T122	V118M	118	Missense	distal	-4	no	83.571	83.697	EPSD	CCLE	73.015	Up-regulation
CK1_CK1_CK1-A_CSNK1A1_ST	P02730	SLC4A1	P48729	CSNK1A1	S303	H309Y	309	Missense	distal	6	no	20.723	20.410	PhosphoSitePlus;EPSD	CCLE	20.411	Loss
CK1_CK1_CK1-A_CSNK1A1_ST	P55316	FOXG1	P48729	CSNK1A1	S228	W225C	225	Missense	distal	-3	no	23.055	19.679	EPSD	CCLE	20.411	Loss
CK1_CK1_CK1-A_CSNK1A1_ST	Q13148	TARDBP	P48729	CSNK1A1	S91	V94L	94	Missense	distal	3	no	21.307	20.139	EPSD;PhosphoSitePlus	CCLE	20.411	Loss
CK1_CK1_CK1-A_CSNK1A1_ST	Q13148	TARDBP	P48729	CSNK1A1	S387	N390S	390	Missense	distal	3	no	21.016	23.494	EPSD;PhosphoSitePlus	CCLE	20.411	Up-regulation
CK1_CK1_CK1-A_CSNK1A1_ST	Q13148	TARDBP	P48729	CSNK1A1	S389	N390S	390	Missense	proximal	1	no	24.096	24.152	EPSD;PhosphoSitePlus	CCLE	20.411	Up-regulation
CK1_CK1_CK1-A_CSNK1A1_ST	Q13148	TARDBP	P48729	CSNK1A1	S393	N390S	390	Missense	distal	-3	no	19.988	24.897	EPSD;PhosphoSitePlus	CCLE	20.411	Gain
CK1_CK1_CK1-A_CSNK1A1_ST	Q13148	TARDBP	P48729	CSNK1A1	S395	N390S	390	Missense	distal	-5	no	20.250	20.421	EPSD;PhosphoSitePlus	CCLE	20.411	Gain
CK1_CK1_CK1-A_CSNK1A1_ST	P98177	FOXO4	P48729	CSNK1A1	S153	L160M	160	Missense	distal	7	no	23.864	23.884	EPSD	CCLE	20.411	Up-regulation
CK1_CK1_CK1-A_CSNK1A1_ST	P98177	FOXO4	P48729	CSNK1A1	S197	R194Q	194	Missense	distal	-3	no	20.505	21.460	EPSD	CCLE	20.411	Up-regulation
CK1_CK1_CK1-A_CSNK1A1_ST	P98177	FOXO4	P48729	CSNK1A1	S265	P258Q	258	Missense	distal	-7	no	24.580	25.334	EPSD;PhosphoSitePlus	CCLE	20.411	Up-regulation
CK1_CK1_CK1-A_CSNK1A1_ST	P98177	FOXO4	P48729	CSNK1A1	S317	L318M	318	Missense	proximal	1	no	22.231	21.910	EPSD	CCLE	20.411	Down-regulation
CK1_CK1_CK1-A_CSNK1A1_ST	P98177	FOXO4	P48729	CSNK1A1	S320	L318M	318	Missense	proximal	-2	no	20.175	21.759	EPSD	CCLE	20.411	Gain
CK1_CK1_CK1-A_CSNK1A1_ST	Q9BXL7	CARD11	P48729	CSNK1A1	S541	A534N	534	Missense	distal	-7	no	22.394	22.075	EPSD	CCLE	20.411	Down-regulation
CK1_CK1_CK1-A_CSNK1A1_ST	Q9BXL7	CARD11	P48729	CSNK1A1	S559	E566G	566	Missense	distal	7	no	20.325	20.471	EPSD	CCLE	20.411	Gain
CK1_CK1_CK1-A_CSNK1A1_ST	Q9Y4G8	RAPGEF2	P48729	CSNK1A1	S1095	S1089F	1089	Missense	distal	-6	no	21.168	19.954	EPSD	CCLE	20.411	Loss
CK1_CK1_CK1-A_CSNK1A1_ST	P17931	LGALS3	P48729	CSNK1A1	S12	L11I	11	Missense	proximal	-1	no	22.212	23.244	EPSD;PhosphoSitePlus	CCLE	20.411	Up-regulation
CK1_CK1_CK1-A_CSNK1A1_ST	Q13009	TIAM1	P48729	CSNK1A1	S219	R221W	221	Missense	proximal	2	no	20.495	20.244	EPSD	CCLE	20.411	Loss
CK1_CK1_CK1-A_CSNK1A1_ST	Q13009	TIAM1	P48729	CSNK1A1	S483	N488D	488	Missense	distal	5	no	25.529	25.283	EPSD	CCLE	20.411	Down-regulation
CK1_CK1_CK1-A_CSNK1A1_ST	Q13009	TIAM1	P48729	CSNK1A1	S1018	P1021S	1021	Missense	distal	3	no	16.704	20.969	EPSD	CCLE	20.411	Gain
CK1_CK1_CK1-A_CSNK1A1_ST	Q13009	TIAM1	P48729	CSNK1A1	S1020	P1021H	1021	Missense	proximal	1	no	23.833	23.541	EPSD	CCLE	20.411	Down-regulation
CK1_CK1_CK1-A_CSNK1A1_ST	Q13009	TIAM1	P48729	CSNK1A1	S1020	P1021S	1021	Missense	proximal	1	no	23.833	23.681	EPSD	CCLE	20.411	Down-regulation
CK1_CK1_CK1-A_CSNK1A1_ST	Q13009	TIAM1	P48729	CSNK1A1	S1024	P1021S	1021	Missense	distal	-3	no	15.900	22.087	EPSD	CCLE	20.411	Gain
CK1_CK1_CK1-A_CSNK1A1_ST	Q12968	NFATC3	P48729	CSNK1A1	T204	S211Y	211	Missense	distal	7	no	20.405	20.658	EPSD;PhosphoSitePlus	CCLE	20.411	Gain
CK1_CK1_CK1-A_CSNK1A1_ST	Q12968	NFATC3	P48729	CSNK1A1	T210	S211Y	211	Missense	proximal	1	no	20.562	20.493	EPSD;PhosphoSitePlus	CCLE	20.411	Down-regulation
CK1_CK1_CK1-A_CSNK1A1_ST	Q12968	NFATC3	P48729	CSNK1A1	S215	S211Y	211	Missense	distal	-4	no	20.754	18.202	EPSD;PhosphoSitePlus	CCLE	20.411	Loss
CK1_CK1_CK1-A_CSNK1A1_ST	Q12968	NFATC3	P48729	CSNK1A1	S215	E222K	222	Missense	distal	7	no	20.754	20.884	EPSD;PhosphoSitePlus	CCLE	20.411	Up-regulation
CK1_CK1_CK1-A_CSNK1A1_ST	Q12968	NFATC3	P48729	CSNK1A1	S269	S265L	265	Missense	distal	-4	no	20.697	16.890	EPSD	CCLE	20.411	Loss
CK1_CK1_CK1-A_CSNK1A1_ST	O60716	CTNND1	P48729	CSNK1A1	S252	A250E	250	Missense	proximal	-2	no	20.799	21.757	EPSD	CCLE	20.411	Up-regulation
CK1_CK1_CK1-A_CSNK1A1_ST	O60716	CTNND1	P48729	CSNK1A1	S484	M487I	487	Missense	distal	3	no	19.468	21.030	EPSD	CCLE	20.411	Gain
CK1_CK1_CK1-A_CSNK1A1_ST	Q9NRF8	CTPS2	P48729	CSNK1A1	S576	R579G	579	Missense	distal	3	no	19.729	22.620	EPSD	CCLE	20.411	Gain
CK1_CK1_CK1-A_CSNK1A1_ST	P51532	SMARCA4	P48729	CSNK1A1	S111	P108A	108	Missense	distal	-3	no	20.572	22.304	EPSD	CCLE	20.411	Up-regulation
CK1_CK1_CK1-A_CSNK1A1_ST	P51532	SMARCA4	P48729	CSNK1A1	S699	A703V	703	Missense	distal	4	no	25.806	25.735	EPSD	CCLE	20.411	Down-regulation
CK1_CK1_CK1-A_CSNK1A1_ST	P51532	SMARCA4	P48729	CSNK1A1	S1421	D1416N	1416	Missense	distal	-5	no	20.493	20.243	EPSD	CCLE	20.411	Loss
CK1_CK1_CK1-A_CSNK1A1_ST	P51532	SMARCA4	P48729	CSNK1A1	S1421	D1418Y	1418	Missense	distal	-3	no	20.493	14.147	EPSD	CCLE	20.411	Loss
CK1_CK1_CK1-A_CSNK1A1_ST	P51532	SMARCA4	P48729	CSNK1A1	S1575	D1569N	1569	Missense	distal	-6	no	27.501	26.221	EPSD	CCLE	20.411	Down-regulation
CK1_CK1_CK1-A_CSNK1A1_ST	P51532	SMARCA4	P48729	CSNK1A1	S1575	E1577G	1577	Missense	proximal	2	no	27.501	27.896	EPSD	CCLE	20.411	Up-regulation
CK1_CK1_CK1-A_CSNK1A1_ST	P25054	APC	P48729	CSNK1A1	S1238	L1231V	1231	Missense	distal	-7	no	23.779	22.747	EPSD	CCLE	20.411	Down-regulation
CK1_CK1_CK1-A_CSNK1A1_ST	P25054	APC	P48729	CSNK1A1	S1238	P1233L	1233	Missense	distal	-5	no	23.779	23.582	EPSD	CCLE	20.411	Down-regulation
CK1_CK1_CK1-A_CSNK1A1_ST	P25054	APC	P48729	CSNK1A1	S1392	D1394H	1394	Missense	proximal	2	no	21.764	20.290	EPSD	CCLE	20.411	Loss
CK1_CK1_CK1-A_CSNK1A1_ST	P25054	APC	P48729	CSNK1A1	S1395	D1394H	1394	Missense	proximal	-1	no	21.416	19.845	EPSD	CCLE	20.411	Loss
CK1_CK1_CK1-A_CSNK1A1_ST	P25054	APC	P48729	CSNK1A1	S1398	D1394H	1394	Missense	distal	-4	no	25.131	20.063	EPSD	CCLE	20.411	Loss
CK1_CK1_CK1-A_CSNK1A1_ST	P25054	APC	P48729	CSNK1A1	S1656	T1661K	1661	Missense	distal	5	no	20.731	20.931	EPSD	CCLE	20.411	Up-regulation
CK1_CK1_CK1-A_CSNK1A1_ST	P25054	APC	P48729	CSNK1A1	S2034	D2033E	2033	Missense	proximal	-1	no	22.264	22.894	EPSD	CCLE	20.411	Up-regulation
CK1_CK1_CK1-A_CSNK1A1_ST	P25054	APC	P48729	CSNK1A1	S2768	S2768R	2768	Missense	central	0	yes	20.854	0.000	EPSD	CCLE	20.411	Loss
CK1_CK1_CK1-A_CSNK1A1_ST	P25054	APC	P48729	CSNK1A1	S2771	S2768R	2768	Missense	distal	-3	no	22.693	18.468	EPSD	CCLE	20.411	Loss
CK1_CK1_CK1-A_CSNK1A1_ST	P08238	HSP90AB1	P48729	CSNK1A1	S159	S160T	160	Missense	proximal	1	no	22.549	22.558	EPSD	CCLE	20.411	Up-regulation
CK1_CK1_CK1-A_CSNK1A1_ST	P08238	HSP90AB1	P48729	CSNK1A1	T166	S160T	160	Missense	distal	-6	no	20.706	20.325	EPSD	CCLE	20.411	Loss
CK1_CK1_CK1-A_CSNK1A1_ST	O75581	LRP6	P48729	CSNK1A1	S1435	L1432M	1432	Missense	distal	-3	no	16.546	20.884	EPSD	CCLE	20.411	Gain
CK1_CK1_CK1-A_CSNK1A1_ST	O75581	LRP6	P48729	CSNK1A1	S1444	S1450T	1450	Missense	distal	6	no	22.395	22.291	EPSD	CCLE	20.411	Down-regulation
CK1_CK1_CK1-A_CSNK1A1_ST	Q12778	FOXO1	P48729	CSNK1A1	S322	S325T	325	Missense	distal	3	no	25.541	23.107	EPSD;PhosphoSitePlus	CCLE	20.411	Down-regulation
CK1_CK1_CK1-A_CSNK1A1_ST	Q12778	FOXO1	P48729	CSNK1A1	S432	M431V	431	Missense	proximal	-1	no	20.532	19.913	EPSD	CCLE	20.411	Loss
CK1_CK1_CK1-A_CSNK1A1_ST	P40337	VHL	P48729	CSNK1A1	S33	S33L	33	Missense	central	0	yes	25.228	0.000	EPSD	CCLE	20.411	Loss
CK1_CK1_CK1-A_CSNK1A1_ST	P40337	VHL	P48729	CSNK1A1	S38	S33L	33	Missense	distal	-5	no	24.264	23.635	EPSD	CCLE	20.411	Down-regulation
CK1_CK1_CK1-A_CSNK1A1_ST	P40337	VHL	P48729	CSNK1A1	S72	E70D	70	Missense	proximal	-2	no	21.150	21.035	PhosphoSitePlus	CCLE	20.411	Down-regulation
CK1_CK1_CK1-A_CSNK1A1_ST	Q13501	SQSTM1	P48729	CSNK1A1	S176	P171L	171	Missense	distal	-5	no	20.545	20.349	EPSD	CCLE	20.411	Loss
CK1_CK1_CK1-A_CSNK1A1_ST	Q13501	SQSTM1	P48729	CSNK1A1	S282	K281R	281	Missense	proximal	-1	no	21.022	21.143	EPSD	CCLE	20.411	Up-regulation
CK1_CK1_CK1-A_CSNK1A1_ST	Q13501	SQSTM1	P48729	CSNK1A1	S361	S361F	361	Missense	central	0	yes	23.967	0.000	EPSD	CCLE	20.411	Loss
CK1_CK1_CK1-A_CSNK1A1_ST	Q13501	SQSTM1	P48729	CSNK1A1	S365	S361F	361	Missense	distal	-4	no	20.464	18.814	EPSD	CCLE	20.411	Loss
CK1_CK1_CK1-A_CSNK1A1_ST	Q8TB45	DEPTOR	P48729	CSNK1A1	S15	A22T	22	Missense	distal	7	no	24.411	24.391	EPSD	CCLE	20.411	Down-regulation
CK1_CK1_CK1-A_CSNK1A1_ST	Q8TB45	DEPTOR	P48729	CSNK1A1	S17	A22T	22	Missense	distal	5	no	26.229	26.122	EPSD	CCLE	20.411	Down-regulation
CK1_CK1_CK1-A_CSNK1A1_ST	Q8TB45	DEPTOR	P48729	CSNK1A1	S286	S292R	292	Missense	distal	6	no	23.573	23.380	EPSD;PhosphoSitePlus	CCLE	20.411	Down-regulation
CK1_CK1_CK1-A_CSNK1A1_ST	Q8TB45	DEPTOR	P48729	CSNK1A1	S286	S293N	293	Missense	distal	7	no	23.573	23.618	EPSD;PhosphoSitePlus	CCLE	20.411	Up-regulation
CK1_CK1_CK1-A_CSNK1A1_ST	O60346	PHLPP1	P48729	CSNK1A1	S141	A145T	145	Missense	distal	4	no	21.182	21.171	EPSD	CCLE	20.411	Down-regulation
CK1_CK1_CK1-A_CSNK1A1_ST	O60346	PHLPP1	P48729	CSNK1A1	S142	A145T	145	Missense	distal	3	no	23.204	23.001	EPSD	CCLE	20.411	Down-regulation
CK1_CK1_CK1-A_CSNK1A1_ST	O60346	PHLPP1	P48729	CSNK1A1	S143	A145T	145	Missense	proximal	2	no	21.270	21.308	EPSD	CCLE	20.411	Up-regulation
CK1_CK1_CK1-A_CSNK1A1_ST	O60346	PHLPP1	P48729	CSNK1A1	S143	H150Q	150	Missense	distal	7	no	21.270	21.043	EPSD	CCLE	20.411	Down-regulation
CK1_CK1_CK1-A_CSNK1A1_ST	O60346	PHLPP1	P48729	CSNK1A1	S144	A145T	145	Missense	proximal	1	no	21.796	21.841	EPSD	CCLE	20.411	Up-regulation
CK1_CK1_CK1-A_CSNK1A1_ST	O60346	PHLPP1	P48729	CSNK1A1	S144	H150Q	150	Missense	distal	6	no	21.796	21.784	EPSD	CCLE	20.411	Down-regulation
CK1_CK1_CK1-A_CSNK1A1_ST	O60346	PHLPP1	P48729	CSNK1A1	S1381	G1375W	1375	Missense	distal	-6	no	25.473	24.665	EPSD;PhosphoSitePlus	CCLE	20.411	Down-regulation
CK1_CK1_CK1-A_CSNK1A1_ST	O60346	PHLPP1	P48729	CSNK1A1	S1381	S1381P	1381	Missense	central	0	yes	25.473	0.000	EPSD;PhosphoSitePlus	CCLE	20.411	Loss
CK1_CK1_CK1-A_CSNK1A1_ST	P07900	HSP90AA1	P48729	CSNK1A1	S164	T171I	171	Missense	distal	7	no	22.439	22.289	EPSD	CCLE	20.411	Down-regulation
CK1_CK1_CK1-A_CSNK1A1_ST	P07900	HSP90AA1	P48729	CSNK1A1	S164	A161V	161	Missense	distal	-3	no	22.439	21.213	EPSD	CCLE	20.411	Down-regulation
CK1_CK1_CK1-A_CSNK1A1_ST	P07900	HSP90AA1	P48729	CSNK1A1	S164	Q159R	159	Missense	distal	-5	no	22.439	21.642	EPSD	CCLE	20.411	Down-regulation
CK1_CK1_CK1-A_CSNK1A1_ST	P07900	HSP90AA1	P48729	CSNK1A1	S165	T171I	171	Missense	distal	6	no	26.788	26.889	EPSD	CCLE	20.411	Up-regulation
CK1_CK1_CK1-A_CSNK1A1_ST	P07900	HSP90AA1	P48729	CSNK1A1	S165	A161V	161	Missense	distal	-4	no	26.788	25.604	EPSD	CCLE	20.411	Down-regulation
CK1_CK1_CK1-A_CSNK1A1_ST	P07900	HSP90AA1	P48729	CSNK1A1	S165	Q159R	159	Missense	distal	-6	no	26.788	26.599	EPSD	CCLE	20.411	Down-regulation
CK1_CK1_CK1-A_CSNK1A1_ST	P07900	HSP90AA1	P48729	CSNK1A1	S263	E265K	265	Missense	proximal	2	no	22.114	21.139	EPSD	CCLE	20.411	Down-regulation
CK1_CK1_CK1-A_CSNK1A1_ST	P07900	HSP90AA1	P48729	CSNK1A1	T305	Y309C	309	Missense	distal	4	no	21.151	21.174	EPSD	CCLE	20.411	Up-regulation
CK1_CK1_CK1-A_CSNK1A1_ST	P07900	HSP90AA1	P48729	CSNK1A1	S476	D479N	479	Missense	distal	3	no	24.531	21.331	EPSD	CCLE	20.411	Down-regulation
CK1_CK1_CK1-A_CSNK1A1_ST	P07900	HSP90AA1	P48729	CSNK1A1	T704	A710V	710	Missense	distal	6	no	24.123	24.020	EPSD	CCLE	20.411	Down-regulation
CK1_CK1_CK1-A_CSNK1A1_ST	P07900	HSP90AA1	P48729	CSNK1A1	T704	A705V	705	Missense	proximal	1	no	24.123	24.145	EPSD	CCLE	20.411	Up-regulation
CK1_CK1_CK1-A_CSNK1A1_ST	P07900	HSP90AA1	P48729	CSNK1A1	S726	L719F	719	Missense	distal	-7	no	21.702	21.964	PhosphoSitePlus;EPSD	CCLE	20.411	Up-regulation
CK1_CK1_CK1-A_CSNK1A1_ST	P01106	MYC	P48729	CSNK1A1	S252	S252C	252	Missense	central	0	yes	22.474	0.000	PhosphoSitePlus;EPSD	CCLE	20.411	Loss
CK1_CK1_CK1-A_CSNK1A1_ST	Q9H6E5	TUT1	P48729	CSNK1A1	S750	A754G	754	Missense	distal	4	no	27.025	27.078	EPSD	CCLE	20.411	Up-regulation
CK1_CK1_CK1-A_CSNK1A1_ST	P42892	ECE1	P48729	CSNK1A1	S36	P42H	42	Missense	distal	6	no	23.841	23.803	PhosphoSitePlus;EPSD	CCLE	20.411	Down-regulation
CK1_CK1_CK1-A_CSNK1A1_ST	O94916	NFAT5	P48729	CSNK1A1	S301	V305A	305	Missense	distal	4	no	22.571	22.642	EPSD	CCLE	20.411	Up-regulation
TKL_RIPK_RIPK1_ST	Q13546	RIPK1	Q13546	RIPK1	S333	A327T	327	Missense	distal	-6	no	2.990	2.404	EPSD	CCLE	2.812	Loss
TKL_RIPK_RIPK1_ST	Q5VWQ8	DAB2IP	Q13546	RIPK1	S856	H854Y	854	Missense	proximal	-2	no	3.263	3.372	EPSD	CCLE	2.812	Up-regulation
TKL_RIPK_RIPK1_ST	Q5VWQ8	DAB2IP	Q13546	RIPK1	S858	H854Y	854	Missense	distal	-4	no	3.467	3.474	EPSD	CCLE	2.812	Up-regulation
TKL_RIPK_RIPK1_ST	Q5VWQ8	DAB2IP	Q13546	RIPK1	S973	R966Q	966	Missense	distal	-7	no	2.778	2.829	EPSD	CCLE	2.812	Gain
TKL_RIPK_RIPK1_ST	Q5VWQ8	DAB2IP	Q13546	RIPK1	S1031	D1033E	1033	Missense	proximal	2	no	3.671	3.434	EPSD	CCLE	2.812	Down-regulation
CMGC_RCK_MAK_ICK_ST	Q8N122	RPTOR	Q9UPZ9	ICK	S721	R727G	727	Missense	distal	6	no	3.395	3.290	EPSD	CCLE	2.314	Down-regulation
STE_STE20_YSK_STK24_ST	Q7L7X3	TAOK1	Q9Y6E0	STK24	S554	N549T	549	Missense	distal	-5	no	2.901	2.858	EPSD	CCLE	2.432	Down-regulation
CMGC_DYRK_DYRK2_DYRK2_ST	Q13541	EIF4EBP1	Q92630	DYRK2	S65	P66H	66	Missense	proximal	1	no	82.988	-26.241	PhosphoSitePlus;EPSD	CCLE	45.963	Loss
CMGC_DYRK_DYRK2_DYRK2_ST	Q13541	EIF4EBP1	Q92630	DYRK2	T68	P66H	66	Missense	proximal	-2	no	47.168	33.814	EPSD	CCLE	45.963	Loss
CMGC_DYRK_DYRK2_DYRK2_ST	Q13541	EIF4EBP1	Q92630	DYRK2	T70	P66H	66	Missense	distal	-4	no	56.720	55.273	EPSD	CCLE	45.963	Down-regulation
CMGC_DYRK_DYRK2_DYRK2_ST	Q13541	EIF4EBP1	Q92630	DYRK2	S101	R99C	99	Missense	proximal	-2	no	90.431	87.167	EPSD;PhosphoSitePlus	CCLE	45.963	Down-regulation
CMGC_DYRK_DYRK2_DYRK2_ST	O43255	SIAH2	Q92630	DYRK2	S16	P19L	19	Missense	distal	3	no	57.545	55.773	EPSD;PhosphoSitePlus	CCLE	45.963	Down-regulation
CMGC_DYRK_DYRK2_DYRK2_ST	O43255	SIAH2	Q92630	DYRK2	T26	P19L	19	Missense	distal	-7	no	73.200	71.480	EPSD;PhosphoSitePlus	CCLE	45.963	Down-regulation
CMGC_DYRK_DYRK2_DYRK2_ST	O43255	SIAH2	Q92630	DYRK2	T119	L125Q	125	Missense	distal	6	no	81.768	82.401	EPSD;PhosphoSitePlus	CCLE	45.963	Up-regulation
CMGC_DYRK_DYRK2_DYRK2_ST	Q9Y2V2	CARHSP1	Q92630	DYRK2	S2	P8Q	8	Missense	distal	6	no	61.343	61.492	EPSD	CCLE	45.963	Up-regulation
CMGC_DYRK_DYRK2_DYRK2_ST	Q9Y2V2	CARHSP1	Q92630	DYRK2	S17	Q15E	15	Missense	proximal	-2	no	47.111	40.092	EPSD	CCLE	45.963	Loss
CMGC_DYRK_DYRK2_DYRK2_ST	Q9Y2V2	CARHSP1	Q92630	DYRK2	S41	R47W	47	Missense	distal	6	no	79.293	79.320	PhosphoSitePlus;EPSD	CCLE	45.963	Up-regulation
CMGC_DYRK_DYRK2_DYRK2_ST	Q9Y2V2	CARHSP1	Q92630	DYRK2	T54	V55L	55	Missense	proximal	1	no	48.708	8.525	EPSD	CCLE	45.963	Loss
CMGC_DYRK_DYRK2_DYRK2_ST	Q9Y2V2	CARHSP1	Q92630	DYRK2	T54	R47W	47	Missense	distal	-7	no	48.708	49.361	EPSD	CCLE	45.963	Up-regulation
CMGC_DYRK_DYRK2_DYRK2_ST	Q9Y2V2	CARHSP1	Q92630	DYRK2	S141	T135S	135	Missense	distal	-6	no	54.435	54.606	EPSD	CCLE	45.963	Up-regulation
CMGC_DYRK_DYRK2_DYRK2_ST	O43602	DCX	Q92630	DYRK2	S287	A286V	286	Missense	proximal	-1	no	57.697	57.972	EPSD	CCLE	45.963	Up-regulation
CMGC_DYRK_DYRK2_DYRK2_ST	O43602	DCX	Q92630	DYRK2	T289	A286V	286	Missense	distal	-3	no	59.635	54.425	EPSD	CCLE	45.963	Down-regulation
CMGC_DYRK_DYRK2_DYRK2_ST	O43602	DCX	Q92630	DYRK2	S304	P307Q	307	Missense	distal	3	no	52.862	51.642	EPSD	CCLE	45.963	Down-regulation
CMGC_DYRK_DYRK2_DYRK2_ST	O43602	DCX	Q92630	DYRK2	S306	P307Q	307	Missense	proximal	1	no	91.991	47.117	PhosphoSitePlus	CCLE	45.963	Down-regulation
CMGC_DYRK_DYRK2_DYRK2_ST	O43602	DCX	Q92630	DYRK2	S310	P307Q	307	Missense	distal	-3	no	47.527	45.332	EPSD	CCLE	45.963	Loss
CMGC_DYRK_DYRK2_DYRK2_ST	O75449	KATNA1	Q92630	DYRK2	T441	T441I	441	Missense	central	0	yes	47.492	0.000	EPSD	CCLE	45.963	Loss
CMGC_DYRK_DYRK2_DYRK2_ST	P04637	TP53	Q92630	DYRK2	S33	E28Q	28	Missense	distal	-5	no	50.772	50.005	EPSD	CCLE	45.963	Down-regulation
CMGC_DYRK_DYRK2_DYRK2_ST	Q14195	DPYSL3	Q92630	DYRK2	S308	D315N	315	Missense	distal	7	no	45.486	46.030	EPSD	CCLE	45.963	Gain
CMGC_DYRK_DYRK2_DYRK2_ST	Q14195	DPYSL3	Q92630	DYRK2	S402	S407G	407	Missense	distal	5	no	46.800	45.993	EPSD	CCLE	45.963	Down-regulation
CMGC_DYRK_DYRK2_DYRK2_ST	Q14195	DPYSL3	Q92630	DYRK2	S402	S405A	405	Missense	distal	3	no	46.800	45.298	EPSD	CCLE	45.963	Loss
CMGC_DYRK_DYRK2_DYRK2_ST	Q14195	DPYSL3	Q92630	DYRK2	S553	V549F	549	Missense	distal	-4	no	62.987	57.630	EPSD	CCLE	45.963	Down-regulation
CMGC_DYRK_DYRK2_DYRK2_ST	Q16555	DPYSL2	Q92630	DYRK2	T555	P551L	551	Missense	distal	-4	no	49.385	45.951	EPSD	CCLE	45.963	Loss
CMGC_DYRK_DYRK2_DYRK2_ST	P10636	MAPT	Q92630	DYRK2	S68	A66V	66	Missense	proximal	-2	no	50.190	53.902	EPSD	CCLE	45.963	Up-regulation
CMGC_DYRK_DYRK2_DYRK2_ST	P10636	MAPT	Q92630	DYRK2	T69	A66V	66	Missense	distal	-3	no	53.844	48.634	EPSD	CCLE	45.963	Down-regulation
CMGC_DYRK_DYRK2_DYRK2_ST	P10636	MAPT	Q92630	DYRK2	S171	P170F	170	Missense	proximal	-1	no	44.056	46.748	EPSD	CCLE	45.963	Gain
CMGC_DYRK_DYRK2_DYRK2_ST	P10636	MAPT	Q92630	DYRK2	S214	D221Y	221	Missense	distal	7	no	65.937	62.370	EPSD	CCLE	45.963	Down-regulation
CMGC_DYRK_DYRK2_DYRK2_ST	P10636	MAPT	Q92630	DYRK2	S235	P234S	234	Missense	proximal	-1	no	48.540	50.024	EPSD	CCLE	45.963	Up-regulation
CMGC_DYRK_DYRK2_DYRK2_ST	P10636	MAPT	Q92630	DYRK2	S235	D242H	242	Missense	distal	7	no	48.540	42.568	EPSD	CCLE	45.963	Loss
CMGC_DYRK_DYRK2_DYRK2_ST	P10636	MAPT	Q92630	DYRK2	S238	P234S	234	Missense	distal	-4	no	53.612	54.880	EPSD	CCLE	45.963	Up-regulation
CMGC_DYRK_DYRK2_DYRK2_ST	P10636	MAPT	Q92630	DYRK2	S238	D242H	242	Missense	distal	4	no	53.612	53.243	EPSD	CCLE	45.963	Down-regulation
CMGC_DYRK_DYRK2_DYRK2_ST	P10636	MAPT	Q92630	DYRK2	S411	K405R	405	Missense	distal	-6	no	70.167	70.211	EPSD	CCLE	45.963	Up-regulation
CMGC_DYRK_DYRK2_DYRK2_ST	P10636	MAPT	Q92630	DYRK2	S438	V442I	442	Missense	distal	4	no	65.359	65.259	EPSD	CCLE	45.963	Down-regulation
CMGC_DYRK_DYRK2_DYRK2_ST	P10636	MAPT	Q92630	DYRK2	S508	R511H	511	Missense	distal	3	no	55.358	52.352	EPSD	CCLE	45.963	Down-regulation
CMGC_DYRK_DYRK2_DYRK2_ST	P10636	MAPT	Q92630	DYRK2	S519	G518S	518	Missense	proximal	-1	no	57.632	57.487	EPSD	CCLE	45.963	Down-regulation
CMGC_DYRK_DYRK2_DYRK2_ST	P10636	MAPT	Q92630	DYRK2	S519	R526L	526	Missense	distal	7	no	57.632	56.083	EPSD	CCLE	45.963	Down-regulation
CMGC_DYRK_DYRK2_DYRK2_ST	P10636	MAPT	Q92630	DYRK2	T522	G518S	518	Missense	distal	-4	no	60.523	66.989	EPSD	CCLE	45.963	Up-regulation
CMGC_DYRK_DYRK2_DYRK2_ST	P10636	MAPT	Q92630	DYRK2	T522	R526L	526	Missense	distal	4	no	60.523	60.334	EPSD	CCLE	45.963	Down-regulation
CMGC_DYRK_DYRK2_DYRK2_ST	P10636	MAPT	Q92630	DYRK2	T529	R526L	526	Missense	distal	-3	no	87.937	73.449	EPSD	CCLE	45.963	Down-regulation
CMGC_DYRK_DYRK2_DYRK2_ST	P10636	MAPT	Q92630	DYRK2	S552	R559H	559	Missense	distal	7	no	62.365	57.245	EPSD	CCLE	45.963	Down-regulation
CMGC_DYRK_DYRK2_DYRK2_ST	P10636	MAPT	Q92630	DYRK2	S575	K574N	574	Missense	proximal	-1	no	46.233	46.486	EPSD	CCLE	45.963	Up-regulation
CMGC_DYRK_DYRK2_DYRK2_ST	P10636	MAPT	Q92630	DYRK2	S637	D631E	631	Missense	distal	-6	no	55.913	55.986	EPSD	CCLE	45.963	Up-regulation
CMGC_DYRK_DYRK2_DYRK2_ST	P10636	MAPT	Q92630	DYRK2	S721	S717C	717	Missense	distal	-4	no	53.193	57.890	EPSD	CCLE	45.963	Up-regulation
CMGC_DYRK_DYRK2_DYRK2_ST	P10636	MAPT	Q92630	DYRK2	S721	S721C	721	Missense	central	0	yes	53.193	0.000	EPSD	CCLE	45.963	Loss
CMGC_DYRK_DYRK2_DYRK2_ST	P10636	MAPT	Q92630	DYRK2	S721	H724R	724	Missense	distal	3	no	53.193	56.200	EPSD	CCLE	45.963	Up-regulation
CMGC_DYRK_DYRK2_DYRK2_ST	P10636	MAPT	Q92630	DYRK2	S726	H724R	724	Missense	proximal	-2	no	37.481	56.288	EPSD	CCLE	45.963	Gain
CMGC_DYRK_DYRK2_DYRK2_ST	P10636	MAPT	Q92630	DYRK2	S739	Q741K	741	Missense	proximal	2	no	67.423	66.826	EPSD	CCLE	45.963	Down-regulation
CMGC_DYRK_DYRK2_DYRK2_ST	Q9UHD2	TBK1	Q92630	DYRK2	S151	S151F	151	Missense	central	0	yes	46.876	0.000	EPSD	CCLE	45.963	Loss
CMGC_DYRK_DYRK2_DYRK2_ST	Q9UHD2	TBK1	Q92630	DYRK2	S151	V152L	152	Missense	proximal	1	no	46.876	6.693	EPSD	CCLE	45.963	Loss
CMGC_DYRK_DYRK2_DYRK2_ST	Q14194	CRMP1	Q92630	DYRK2	S304	D310N	310	Missense	distal	6	no	57.122	57.418	EPSD	CCLE	45.963	Up-regulation
CMGC_DYRK_DYRK2_DYRK2_ST	Q14194	CRMP1	Q92630	DYRK2	S308	D310N	310	Missense	proximal	2	no	48.268	48.734	EPSD	CCLE	45.963	Up-regulation
AGC_PKC_PKCh_PRKCE_ST	Q16625	OCLN	Q02156	PRKCE	S458	R459C	459	Missense	proximal	1	no	15.821	14.234	EPSD	CCLE	13.948	Down-regulation
AGC_PKC_PKCh_PRKCE_ST	P10636	MAPT	Q02156	PRKCE	S64	A66V	66	Missense	proximal	2	no	13.304	15.722	EPSD	CCLE	13.948	Gain
AGC_PKC_PKCh_PRKCE_ST	P10636	MAPT	Q02156	PRKCE	T167	E161Q	161	Missense	distal	-6	no	14.232	14.244	EPSD	CCLE	13.948	Up-regulation
AGC_PKC_PKCh_PRKCE_ST	P10636	MAPT	Q02156	PRKCE	T167	P170F	170	Missense	distal	3	no	14.232	14.137	EPSD	CCLE	13.948	Down-regulation
AGC_PKC_PKCh_PRKCE_ST	P10636	MAPT	Q02156	PRKCE	T167	G174A	174	Missense	distal	7	no	14.232	15.541	EPSD	CCLE	13.948	Up-regulation
AGC_PKC_PKCh_PRKCE_ST	P10636	MAPT	Q02156	PRKCE	S171	P170F	170	Missense	proximal	-1	no	13.651	14.086	EPSD	CCLE	13.948	Gain
AGC_PKC_PKCh_PRKCE_ST	P10636	MAPT	Q02156	PRKCE	S214	D221Y	221	Missense	distal	7	no	15.548	15.484	EPSD	CCLE	13.948	Down-regulation
AGC_PKC_PKCh_PRKCE_ST	P10636	MAPT	Q02156	PRKCE	S400	K405R	405	Missense	distal	5	no	18.204	17.953	EPSD	CCLE	13.948	Down-regulation
AGC_PKC_PKCh_PRKCE_ST	P10636	MAPT	Q02156	PRKCE	S438	V442I	442	Missense	distal	4	no	14.553	12.834	EPSD	CCLE	13.948	Loss
AGC_PKC_PKCh_PRKCE_ST	P10636	MAPT	Q02156	PRKCE	S554	R559H	559	Missense	distal	5	no	15.711	16.076	EPSD	CCLE	13.948	Up-regulation
AGC_PKC_PKCh_PRKCE_ST	P10636	MAPT	Q02156	PRKCE	S555	R559H	559	Missense	distal	4	no	15.616	12.796	EPSD	CCLE	13.948	Loss
AGC_PKC_PKCh_PRKCE_ST	P10636	MAPT	Q02156	PRKCE	T562	R559H	559	Missense	distal	-3	no	15.090	9.870	EPSD	CCLE	13.948	Loss
AGC_PKC_PKCh_PRKCE_ST	P10636	MAPT	Q02156	PRKCE	S575	K574N	574	Missense	proximal	-1	no	15.947	15.712	EPSD	CCLE	13.948	Down-regulation
AGC_PKC_PKCh_PRKCE_ST	P10636	MAPT	Q02156	PRKCE	S637	D631E	631	Missense	distal	-6	no	14.905	14.871	EPSD	CCLE	13.948	Down-regulation
AGC_PKC_PKCh_PRKCE_ST	P10636	MAPT	Q02156	PRKCE	S726	S721C	721	Missense	distal	-5	no	15.001	14.986	EPSD	CCLE	13.948	Down-regulation
AGC_PKC_PKCh_PRKCE_ST	P10636	MAPT	Q02156	PRKCE	S726	H724R	724	Missense	proximal	-2	no	15.001	17.551	EPSD	CCLE	13.948	Up-regulation
AGC_PKC_PKCh_PRKCE_ST	P10636	MAPT	Q02156	PRKCE	S739	Q741K	741	Missense	proximal	2	no	10.443	16.357	EPSD	CCLE	13.948	Gain
AGC_PKC_PKCh_PRKCE_ST	P10636	MAPT	Q02156	PRKCE	T744	Q741K	741	Missense	distal	-3	no	9.589	15.173	EPSD	CCLE	13.948	Gain
AGC_PKC_PKCh_PRKCE_ST	O75689	ADAP1	Q02156	PRKCE	S87	P90T	90	Missense	distal	3	no	16.708	16.185	EPSD;PhosphoSitePlus	CCLE	13.948	Down-regulation
AGC_PKC_PKCh_PRKCE_ST	Q9H9S0	NANOG	Q02156	PRKCE	S71	P66T	66	Missense	distal	-5	no	16.922	16.918	EPSD	CCLE	13.948	Down-regulation
AGC_PKC_PKCh_PRKCE_ST	Q92934	BAD	Q02156	PRKCE	S75	H73Q	73	Missense	proximal	-2	no	18.907	20.486	PhosphoSitePlus;EPSD	CCLE	13.948	Up-regulation
AGC_PKC_PKCh_PRKCE_ST	Q92934	BAD	Q02156	PRKCE	S75	R70W	70	Missense	distal	-5	no	18.907	18.976	PhosphoSitePlus;EPSD	CCLE	13.948	Up-regulation
AGC_PKC_PKCh_PRKCE_ST	P78536	ADAM17	Q02156	PRKCE	S608	R610H	610	Missense	proximal	2	no	20.655	13.684	EPSD	CCLE	13.948	Loss
AGC_PKC_PKCh_PRKCE_ST	P78536	ADAM17	Q02156	PRKCE	T761	D760A	760	Missense	proximal	-1	no	14.126	14.131	EPSD	CCLE	13.948	Up-regulation
AGC_PKC_PKCh_PRKCE_ST	P43629	KIR3DL1	Q02156	PRKCE	S442	K439N	439	Missense	distal	-3	no	15.499	8.125	EPSD	CCLE	13.948	Loss
AGC_PKC_PKCh_PRKCE_ST	P43629	KIR3DL1	Q02156	PRKCE	S442	V441F	441	Missense	proximal	-1	no	15.499	15.896	EPSD	CCLE	13.948	Up-regulation
AGC_PKC_PKCh_PRKCE_ST	P05783	KRT18	Q02156	PRKCE	T409	R412W	412	Missense	distal	3	no	18.334	17.529	EPSD	CCLE	13.948	Down-regulation
AGC_PKC_PKCh_PRKCE_ST	P05783	KRT18	Q02156	PRKCE	T409	R412L	412	Missense	distal	3	no	18.334	17.948	EPSD	CCLE	13.948	Down-regulation
AGC_PKC_PKCh_PRKCE_ST	O94925	GLS	Q02156	PRKCE	S73	I79T	79	Missense	distal	6	no	17.237	17.225	EPSD	CCLE	13.948	Down-regulation
AGC_PKC_PKCh_PRKCE_ST	O94925	GLS	Q02156	PRKCE	S118	F115V	115	Missense	distal	-3	no	16.628	15.390	EPSD	CCLE	13.948	Down-regulation
AGC_PKC_PKCh_PRKCE_ST	P46940	IQGAP1	Q02156	PRKCE	S280	E283K	283	Missense	distal	3	no	17.797	18.424	EPSD	CCLE	13.948	Up-regulation
AGC_PKC_PKCh_PRKCE_ST	P46940	IQGAP1	Q02156	PRKCE	S360	P365L	365	Missense	distal	5	no	17.160	17.037	EPSD	CCLE	13.948	Down-regulation
AGC_PKC_PKCh_PRKCE_ST	P46940	IQGAP1	Q02156	PRKCE	S962	K965T	965	Missense	distal	3	no	14.637	13.718	EPSD	CCLE	13.948	Loss
AGC_PKC_PKCh_PRKCE_ST	P46940	IQGAP1	Q02156	PRKCE	S1443	D1447N	1447	Missense	distal	4	no	23.160	22.552	PhosphoSitePlus	CCLE	13.948	Down-regulation
AGC_PKC_PKCh_PRKCE_ST	P05091	ALDH2	Q02156	PRKCE	S296	P291A	291	Missense	distal	-5	no	14.408	14.422	EPSD;PhosphoSitePlus	CCLE	13.948	Up-regulation
AGC_PKC_PKCh_PRKCE_ST	Q15139	PRKD1	Q02156	PRKCE	S910	G906N	906	Missense	distal	-4	no	14.354	14.353	EPSD	CCLE	13.948	Down-regulation
AGC_PKC_PKCh_PRKCE_ST	Q9BR76	CORO1B	Q02156	PRKCE	S407	R402Q	402	Missense	distal	-5	no	15.496	15.507	EPSD	CCLE	13.948	Up-regulation
AGC_PKC_PKCh_PRKCE_ST	P05556	ITGB1	Q02156	PRKCE	S61	G57R	57	Missense	distal	-4	no	16.146	15.833	EPSD	CCLE	13.948	Down-regulation
AGC_PKC_PKCh_PRKCE_ST	P05556	ITGB1	Q02156	PRKCE	S61	E56G	56	Missense	distal	-5	no	16.146	16.152	EPSD	CCLE	13.948	Up-regulation
AGC_PKC_PKCh_PRKCE_ST	P05556	ITGB1	Q02156	PRKCE	S785	V787A	787	Missense	proximal	2	no	16.060	13.641	EPSD	CCLE	13.948	Loss
AGC_PKC_PKCh_PRKCE_ST	P05556	ITGB1	Q02156	PRKCE	T788	V787A	787	Missense	proximal	-1	no	15.986	16.183	PhosphoSitePlus;EPSD	CCLE	13.948	Up-regulation
AGC_PKC_PKCh_PRKCE_ST	P05556	ITGB1	Q02156	PRKCE	T789	V787A	787	Missense	proximal	-2	no	14.997	14.833	EPSD;PhosphoSitePlus	CCLE	13.948	Down-regulation
AGC_PKC_PKCh_PRKCE_ST	Q96GD4	AURKB	Q02156	PRKCE	S22	L24V	24	Missense	proximal	2	no	12.954	15.839	EPSD	CCLE	13.948	Gain
AGC_PKC_PKCh_PRKCE_ST	P28329	CHAT	Q02156	PRKCE	S473	A471V	471	Missense	proximal	-2	no	15.176	15.340	EPSD	CCLE	13.948	Up-regulation
AGC_PKC_PKCh_PRKCE_ST	P28329	CHAT	Q02156	PRKCE	S473	P480F	480	Missense	distal	7	no	15.176	16.137	EPSD	CCLE	13.948	Up-regulation
AGC_PKC_PKCh_PRKCE_ST	P28329	CHAT	Q02156	PRKCE	S558	A557E	557	Missense	proximal	-1	no	17.756	18.174	EPSD	CCLE	13.948	Up-regulation
AGC_PKC_PKCh_PRKCE_ST	P28329	CHAT	Q02156	PRKCE	T574	A579T	579	Missense	distal	5	no	17.341	17.399	EPSD	CCLE	13.948	Up-regulation
AGC_PKC_PKCh_PRKCE_ST	P28329	CHAT	Q02156	PRKCE	T574	A579D	579	Missense	distal	5	no	17.341	17.243	EPSD	CCLE	13.948	Down-regulation
AGC_PKC_PKCh_PRKCE_ST	P28329	CHAT	Q02156	PRKCE	S594	V591L	591	Missense	distal	-3	no	16.427	15.806	EPSD	CCLE	13.948	Down-regulation
AGC_PKC_PKCh_PRKCE_ST	P17302	GJA1	Q02156	PRKCE	S244	P246T	246	Missense	proximal	2	no	15.603	11.418	EPSD	CCLE	13.948	Loss
AGC_PKC_PKCh_PRKCE_ST	P15336	ATF2	Q02156	PRKCE	S484	E486Q	486	Missense	proximal	2	no	14.382	15.134	EPSD	CCLE	13.948	Up-regulation
AGC_PKC_PKCh_PRKCE_ST	P15336	ATF2	Q02156	PRKCE	S490	E486Q	486	Missense	distal	-4	no	14.467	14.492	EPSD	CCLE	13.948	Up-regulation
AGC_PKC_PKCh_PRKCE_ST	Q16612	NREP	Q02156	PRKCE	S59	R58H	58	Missense	proximal	-1	no	17.731	16.393	PhosphoSitePlus	CCLE	13.948	Down-regulation
AGC_PKC_PKCh_PRKCE_ST	Q16612	NREP	Q02156	PRKCE	S59	R58S	58	Missense	proximal	-1	no	17.731	17.362	PhosphoSitePlus	CCLE	13.948	Down-regulation
AGC_PKC_PKCh_PRKCE_ST	O60716	CTNND1	Q02156	PRKCE	S252	A250E	250	Missense	proximal	-2	no	15.323	15.560	EPSD	CCLE	13.948	Up-regulation
AGC_PKC_PKCh_PRKCE_ST	O60716	CTNND1	Q02156	PRKCE	S484	M487I	487	Missense	distal	3	no	18.581	18.261	EPSD	CCLE	13.948	Down-regulation
STE_STE20_MST_STK3_ST	P00519	ABL1	Q13188	STK3	T532	E527K	527	Missense	distal	-5	no	58.019	54.664	EPSD	CCLE	55.172	Loss
STE_STE20_MST_STK3_ST	P00519	ABL1	Q13188	STK3	T532	K531N	531	Missense	proximal	-1	no	58.019	58.208	EPSD	CCLE	55.172	Up-regulation
STE_STE20_MST_STK3_ST	P00519	ABL1	Q13188	STK3	T597	N598S	598	Missense	proximal	1	no	48.606	60.182	EPSD	CCLE	55.172	Gain
STE_STE20_MST_STK3_ST	P00519	ABL1	Q13188	STK3	T751	G753V	753	Missense	proximal	2	no	57.618	57.559	EPSD	CCLE	55.172	Down-regulation
STE_STE20_MST_STK3_ST	P00519	ABL1	Q13188	STK3	T751	H755Q	755	Missense	distal	4	no	57.618	55.918	EPSD	CCLE	55.172	Down-regulation
STE_STE20_MST_STK3_ST	P00519	ABL1	Q13188	STK3	T814	T814A	814	Missense	central	0	yes	55.272	0.000	EPSD	CCLE	55.172	Loss
STE_STE20_MST_STK3_ST	P00519	ABL1	Q13188	STK3	T814	L818I	818	Missense	distal	4	no	55.272	57.008	EPSD	CCLE	55.172	Up-regulation
STE_STE20_MST_STK3_ST	P00519	ABL1	Q13188	STK3	S936	T935M	935	Missense	proximal	-1	no	71.838	72.126	EPSD	CCLE	55.172	Up-regulation
STE_STE20_MST_STK3_ST	Q9H4B6	SAV1	Q13188	STK3	S36	H40R	40	Missense	distal	4	no	94.363	93.615	PhosphoSitePlus;EPSD	CCLE	55.172	Down-regulation
STE_STE20_MST_STK3_ST	P51955	NEK2	Q13188	STK3	S438	S438C	438	Missense	central	0	yes	73.331	0.000	EPSD;PhosphoSitePlus	CCLE	55.172	Loss
STE_STE20_MST_STK3_ST	O95835	LATS1	Q13188	STK3	S909	N915S	915	Missense	distal	6	no	108.035	112.121	PhosphoSitePlus;EPSD	CCLE	55.172	Up-regulation
STE_STE20_MST_STK3_ST	Q13188	STK3	Q13188	STK3	S333	A339T	339	Missense	distal	6	no	58.060	55.689	EPSD	CCLE	55.172	Down-regulation
STE_STE20_MST_STK3_ST	P46937	YAP1	Q13188	STK3	S274	I273T	273	Missense	proximal	-1	no	56.361	54.443	EPSD	CCLE	55.172	Loss
Atypical_PIKK_ATR_ATR_ST	P25205	MCM3	Q13535	ATR	S535	N533I	533	Missense	proximal	-2	no	16.849	16.497	PhosphoSitePlus	CCLE	10.658	Down-regulation
Atypical_PIKK_ATR_ATR_ST	P78527	PRKDC	Q13535	ATR	S318	N325D	325	Missense	distal	7	no	12.371	12.146	EPSD	CCLE	10.658	Down-regulation
Atypical_PIKK_ATR_ATR_ST	Q99708	RBBP8	Q13535	ATR	S231	A236S	236	Missense	distal	5	no	15.119	15.108	EPSD	CCLE	10.658	Down-regulation
Atypical_PIKK_ATR_ATR_ST	Q99708	RBBP8	Q13535	ATR	T241	A236S	236	Missense	distal	-5	no	11.558	11.463	EPSD	CCLE	10.658	Down-regulation
Atypical_PIKK_ATR_ATR_ST	Q99708	RBBP8	Q13535	ATR	S327	V325L	325	Missense	proximal	-2	no	10.511	10.957	EPSD	CCLE	10.658	Gain
Atypical_PIKK_ATR_ATR_ST	Q99708	RBBP8	Q13535	ATR	S345	Q352P	352	Missense	distal	7	no	12.001	12.142	EPSD	CCLE	10.658	Up-regulation
Atypical_PIKK_ATR_ATR_ST	Q99708	RBBP8	Q13535	ATR	S593	R591C	591	Missense	proximal	-2	no	11.000	11.230	EPSD	CCLE	10.658	Up-regulation
Atypical_PIKK_ATR_ATR_ST	Q99708	RBBP8	Q13535	ATR	T596	R591C	591	Missense	distal	-5	no	11.187	11.194	EPSD	CCLE	10.658	Up-regulation
Atypical_PIKK_ATR_ATR_ST	Q99708	RBBP8	Q13535	ATR	T596	D601G	601	Missense	distal	5	no	11.187	11.182	EPSD	CCLE	10.658	Down-regulation
Atypical_PIKK_ATR_ATR_ST	Q9UPV0	CEP164	Q13535	ATR	S544	E541D	541	Missense	distal	-3	no	11.835	12.428	EPSD	CCLE	10.658	Up-regulation
Atypical_PIKK_ATR_ATR_ST	Q8WXE1	ATRIP	Q13535	ATR	S68	E61K	61	Missense	distal	-7	no	16.399	16.381	PhosphoSitePlus;EPSD	CCLE	10.658	Down-regulation
Atypical_PIKK_ATR_ATR_ST	Q8WXE1	ATRIP	Q13535	ATR	S68	S68L	68	Missense	central	0	yes	16.399	0.000	PhosphoSitePlus;EPSD	CCLE	10.658	Loss
Atypical_PIKK_ATR_ATR_ST	Q8WXE1	ATRIP	Q13535	ATR	S72	S68L	68	Missense	distal	-4	no	15.127	14.252	EPSD;PhosphoSitePlus	CCLE	10.658	Down-regulation
Atypical_PIKK_ATR_ATR_ST	Q8WXE1	ATRIP	Q13535	ATR	T307	Q308R	308	Missense	proximal	1	no	14.734	7.739	EPSD	CCLE	10.658	Loss
Atypical_PIKK_ATR_ATR_ST	P23508	MCC	Q13535	ATR	S120	E123K	123	Missense	distal	3	no	15.800	15.957	PhosphoSitePlus;EPSD	CCLE	10.658	Up-regulation
Atypical_PIKK_ATR_ATR_ST	P23508	MCC	Q13535	ATR	S179	C181S	181	Missense	proximal	2	no	12.201	13.884	EPSD	CCLE	10.658	Up-regulation
Atypical_PIKK_ATR_ATR_ST	P23508	MCC	Q13535	ATR	S179	K177R	177	Missense	proximal	-2	no	12.201	12.214	EPSD	CCLE	10.658	Up-regulation
Atypical_PIKK_ATR_ATR_ST	P23508	MCC	Q13535	ATR	S182	K177R	177	Missense	distal	-5	no	10.525	10.710	EPSD	CCLE	10.658	Gain
Atypical_PIKK_ATR_ATR_ST	P23508	MCC	Q13535	ATR	S702	E709K	709	Missense	distal	7	no	14.939	15.088	EPSD	CCLE	10.658	Up-regulation
Atypical_PIKK_ATR_ATR_ST	P23508	MCC	Q13535	ATR	S706	E709K	709	Missense	distal	3	no	10.550	10.707	EPSD	CCLE	10.658	Gain
Atypical_PIKK_ATR_ATR_ST	P23508	MCC	Q13535	ATR	S770	V773A	773	Missense	distal	3	no	10.964	10.204	EPSD	CCLE	10.658	Loss
Atypical_PIKK_ATR_ATR_ST	O14757	CHEK1	Q13535	ATR	S345	D351A	351	Missense	distal	6	no	17.127	16.990	EPSD;PhosphoSitePlus	CCLE	10.658	Down-regulation
Atypical_PIKK_ATR_ATR_ST	O14757	CHEK1	Q13535	ATR	S357	D351A	351	Missense	distal	-6	no	14.888	14.933	EPSD	CCLE	10.658	Up-regulation
Atypical_PIKK_ATR_ATR_ST	O14757	CHEK1	Q13535	ATR	S357	Q358R	358	Missense	proximal	1	no	14.888	7.893	EPSD	CCLE	10.658	Loss
Atypical_PIKK_ATR_ATR_ST	Q12888	TP53BP1	Q13535	ATR	S29	E28A	28	Missense	proximal	-1	no	12.223	12.358	EPSD	CCLE	10.658	Up-regulation
Atypical_PIKK_ATR_ATR_ST	Q12888	TP53BP1	Q13535	ATR	S452	S452P	452	Missense	central	0	yes	11.136	0.000	EPSD;PhosphoSitePlus	CCLE	10.658	Loss
Atypical_PIKK_ATR_ATR_ST	Q12888	TP53BP1	Q13535	ATR	S523	L517H	517	Missense	distal	-6	no	14.431	14.410	EPSD	CCLE	10.658	Down-regulation
Atypical_PIKK_ATR_ATR_ST	Q12888	TP53BP1	Q13535	ATR	S784	S782L	782	Missense	proximal	-2	no	12.434	13.137	EPSD	CCLE	10.658	Up-regulation
Atypical_PIKK_ATR_ATR_ST	Q12888	TP53BP1	Q13535	ATR	S1368	S1368R	1368	Missense	central	0	yes	16.115	0.000	EPSD	CCLE	10.658	Loss
Atypical_PIKK_ATR_ATR_ST	Q12888	TP53BP1	Q13535	ATR	S1368	V1367I	1367	Missense	proximal	-1	no	16.115	16.366	EPSD	CCLE	10.658	Up-regulation
Atypical_PIKK_ATR_ATR_ST	Q12888	TP53BP1	Q13535	ATR	S1660	R1658C	1658	Missense	proximal	-2	no	13.393	13.623	EPSD	CCLE	10.658	Up-regulation
Atypical_PIKK_ATR_ATR_ST	Q12888	TP53BP1	Q13535	ATR	S1778	S1778C	1778	Missense	central	0	yes	13.247	0.000	EPSD	CCLE	10.658	Loss
Atypical_PIKK_ATR_ATR_ST	Q96RL1	UIMC1	Q13535	ATR	S662	G655A	655	Missense	distal	-7	no	10.850	10.862	EPSD	CCLE	10.658	Up-regulation
Atypical_PIKK_ATR_ATR_ST	Q96RL1	UIMC1	Q13535	ATR	S677	S684F	684	Missense	distal	7	no	12.139	12.201	EPSD	CCLE	10.658	Up-regulation
Atypical_PIKK_ATR_ATR_ST	P39880	CUX1	Q13535	ATR	T374	P380L	380	Missense	distal	6	no	15.839	15.912	EPSD	CCLE	10.658	Up-regulation
Atypical_PIKK_ATR_ATR_ST	P39880	CUX1	Q13535	ATR	S1312	S1312R	1312	Missense	central	0	yes	12.391	0.000	EPSD	CCLE	10.658	Loss
Atypical_PIKK_ATR_ATR_ST	P39880	CUX1	Q13535	ATR	S1312	G1314C	1314	Missense	proximal	2	no	12.391	9.768	EPSD	CCLE	10.658	Loss
Atypical_PIKK_ATR_ATR_ST	P39880	CUX1	Q13535	ATR	S1312	A1318T	1318	Missense	distal	6	no	12.391	12.670	EPSD	CCLE	10.658	Up-regulation
Atypical_PIKK_ATR_ATR_ST	P39880	CUX1	Q13535	ATR	S1321	G1314C	1314	Missense	distal	-7	no	11.118	10.941	EPSD	CCLE	10.658	Down-regulation
Atypical_PIKK_ATR_ATR_ST	P39880	CUX1	Q13535	ATR	S1321	A1318T	1318	Missense	distal	-3	no	11.118	10.556	EPSD	CCLE	10.658	Loss
Atypical_PIKK_ATR_ATR_ST	P39880	CUX1	Q13535	ATR	S1332	A1329V	1329	Missense	distal	-3	no	12.934	12.535	EPSD	CCLE	10.658	Down-regulation
Atypical_PIKK_ATR_ATR_ST	P39880	CUX1	Q13535	ATR	S1332	S1332G	1332	Missense	central	0	yes	12.934	0.000	EPSD	CCLE	10.658	Loss
Atypical_PIKK_ATR_ATR_ST	P39880	CUX1	Q13535	ATR	S1357	T1352I	1352	Missense	distal	-5	no	16.940	17.131	PhosphoSitePlus	CCLE	10.658	Up-regulation
Atypical_PIKK_ATR_ATR_ST	Q01094	E2F1	Q13535	ATR	S313	G309R	309	Missense	distal	-4	no	14.237	14.457	EPSD	CCLE	10.658	Up-regulation
Atypical_PIKK_ATR_ATR_ST	Q01094	E2F1	Q13535	ATR	S364	R366W	366	Missense	proximal	2	no	10.805	10.452	EPSD	CCLE	10.658	Loss
Atypical_PIKK_ATR_ATR_ST	P04637	TP53	Q13535	ATR	S106	G108V	108	Missense	proximal	2	no	11.409	11.107	EPSD	CCLE	10.658	Down-regulation
Atypical_PIKK_ATR_ATR_ST	Q00987	MDM2	Q13535	ATR	S395	S400N	400	Missense	distal	5	no	15.232	15.236	EPSD	CCLE	10.658	Up-regulation
Atypical_PIKK_ATR_ATR_ST	Q00987	MDM2	Q13535	ATR	S407	S400N	400	Missense	distal	-7	no	15.477	15.343	PhosphoSitePlus	CCLE	10.658	Down-regulation
Atypical_PIKK_ATR_ATR_ST	Q96SD1	DCLRE1C	Q13535	ATR	S553	V558G	558	Missense	distal	5	no	14.312	14.315	EPSD	CCLE	10.658	Up-regulation
Atypical_PIKK_ATR_ATR_ST	Q96SD1	DCLRE1C	Q13535	ATR	S562	V558G	558	Missense	distal	-4	no	15.032	14.983	EPSD	CCLE	10.658	Down-regulation
Atypical_PIKK_ATR_ATR_ST	Q8WVB6	CHTF18	Q13535	ATR	S74	G77D	77	Missense	distal	3	no	17.341	17.410	PhosphoSitePlus	CCLE	10.658	Up-regulation
Atypical_PIKK_ATR_ATR_ST	Q8WVB6	CHTF18	Q13535	ATR	S405	R404H	404	Missense	proximal	-1	no	11.745	11.638	EPSD	CCLE	10.658	Down-regulation
Atypical_PIKK_ATR_ATR_ST	P38398	BRCA1	Q13535	ATR	S316	R315M	315	Missense	proximal	-1	no	13.275	13.318	EPSD	CCLE	10.658	Up-regulation
Atypical_PIKK_ATR_ATR_ST	P38398	BRCA1	Q13535	ATR	S988	F989L	989	Missense	proximal	1	no	9.429	10.680	EPSD	CCLE	10.658	Gain
Atypical_PIKK_ATR_ATR_ST	P38398	BRCA1	Q13535	ATR	S1239	V1234L	1234	Missense	distal	-5	no	14.724	14.808	EPSD	CCLE	10.658	Up-regulation
Atypical_PIKK_ATR_ATR_ST	P38398	BRCA1	Q13535	ATR	S1266	N1272D	1272	Missense	distal	6	no	13.724	13.420	EPSD	CCLE	10.658	Down-regulation
Atypical_PIKK_ATR_ATR_ST	P38398	BRCA1	Q13535	ATR	S1266	C1270Y	1270	Missense	distal	4	no	13.724	13.489	EPSD	CCLE	10.658	Down-regulation
Atypical_PIKK_ATR_ATR_ST	P38398	BRCA1	Q13535	ATR	S1330	M1324V	1324	Missense	distal	-6	no	14.052	14.065	EPSD	CCLE	10.658	Up-regulation
Atypical_PIKK_ATR_ATR_ST	O43543	XRCC2	Q13535	ATR	S262	H268P	268	Missense	distal	6	no	11.284	11.308	EPSD	CCLE	10.658	Up-regulation
Atypical_PIKK_ATR_ATR_ST	O43543	XRCC2	Q13535	ATR	S262	H268N	268	Missense	distal	6	no	11.284	11.720	EPSD	CCLE	10.658	Up-regulation
Atypical_PIKK_ATR_ATR_ST	Q9UBU7	DBF4	Q13535	ATR	S381	Q382P	382	Missense	proximal	1	no	12.738	7.871	EPSD	CCLE	10.658	Loss
Atypical_PIKK_ATR_ATR_ST	Q9BXW9	FANCD2	Q13535	ATR	S29	K30E	30	Missense	proximal	1	no	6.284	11.330	EPSD	CCLE	10.658	Gain
Atypical_PIKK_ATR_ATR_ST	Q9BXW9	FANCD2	Q13535	ATR	S126	R119H	119	Missense	distal	-7	no	10.992	11.044	EPSD	CCLE	10.658	Up-regulation
Atypical_PIKK_ATR_ATR_ST	Q9BXW9	FANCD2	Q13535	ATR	S126	R119P	119	Missense	distal	-7	no	10.992	11.067	EPSD	CCLE	10.658	Up-regulation
Atypical_PIKK_ATR_ATR_ST	P15927	RPA2	Q13535	ATR	S114	N117I	117	Missense	distal	3	no	12.522	12.786	EPSD	CCLE	10.658	Up-regulation
Atypical_PIKK_ATR_ATR_ST	P15927	RPA2	Q13535	ATR	S114	S114N	114	Missense	central	0	yes	12.522	0.000	EPSD	CCLE	10.658	Loss
Atypical_PIKK_ATR_ATR_ST	Q9NZC9	SMARCAL1	Q13535	ATR	S627	Y624C	624	Missense	distal	-3	no	11.757	11.331	EPSD	CCLE	10.658	Down-regulation
Atypical_PIKK_ATR_ATR_ST	Q9NZC9	SMARCAL1	Q13535	ATR	S627	L633P	633	Missense	distal	6	no	11.757	11.684	EPSD	CCLE	10.658	Down-regulation
Atypical_PIKK_ATR_ATR_ST	P54132	BLM	Q13535	ATR	S313	I309F	309	Missense	distal	-4	no	9.768	10.827	EPSD	CCLE	10.658	Gain
Atypical_PIKK_ATR_ATR_ST	P54132	BLM	Q13535	ATR	S314	I309F	309	Missense	distal	-5	no	11.794	11.817	EPSD	CCLE	10.658	Up-regulation
Atypical_PIKK_ATR_ATR_ST	Q8IX01	SUGP2	Q13535	ATR	S224	G223V	223	Missense	proximal	-1	no	10.853	10.780	EPSD	CCLE	10.658	Down-regulation
Atypical_PIKK_ATR_ATR_ST	Q9H6E5	TUT1	Q13535	ATR	S750	A754G	754	Missense	distal	4	no	15.883	16.350	PhosphoSitePlus	CCLE	10.658	Up-regulation
Atypical_PIKK_ATR_ATR_ST	Q13315	ATM	Q13535	ATR	S99	Q95L	95	Missense	distal	-4	no	11.150	10.391	EPSD	CCLE	10.658	Loss
Atypical_PIKK_ATR_ATR_ST	Q13315	ATM	Q13535	ATR	S99	K102N	102	Missense	distal	3	no	11.150	11.052	EPSD	CCLE	10.658	Down-regulation
Atypical_PIKK_ATR_ATR_ST	Q13315	ATM	Q13535	ATR	S200	V194A	194	Missense	distal	-6	no	13.414	13.444	EPSD	CCLE	10.658	Up-regulation
Atypical_PIKK_ATR_ATR_ST	Q13315	ATM	Q13535	ATR	S1981	S1987Y	1987	Missense	distal	6	no	15.195	14.699	PhosphoSitePlus	CCLE	10.658	Down-regulation
Atypical_PIKK_ATR_ATR_ST	O96017	CHEK2	Q13535	ATR	S357	D361G	361	Missense	distal	4	no	12.798	13.619	EPSD	CCLE	10.658	Up-regulation
Atypical_PIKK_ATR_ATR_ST	O96017	CHEK2	Q13535	ATR	T432	S435L	435	Missense	distal	3	no	11.577	10.910	EPSD	CCLE	10.658	Down-regulation
Atypical_PIKK_ATR_ATR_ST	O96017	CHEK2	Q13535	ATR	S500	S505T	505	Missense	distal	5	no	11.225	11.234	EPSD	CCLE	10.658	Up-regulation
Atypical_PIKK_ATR_ATR_ST	Q13535	ATR	Q13535	ATR	S428	N423D	423	Missense	distal	-5	no	12.064	12.090	EPSD	CCLE	10.658	Up-regulation
Atypical_PIKK_ATR_ATR_ST	Q13535	ATR	Q13535	ATR	S776	L770M	770	Missense	distal	-6	no	10.772	10.727	EPSD	CCLE	10.658	Down-regulation
Atypical_PIKK_ATR_ATR_ST	P35568	IRS1	Q13535	ATR	S270	S273L	273	Missense	distal	3	no	14.440	13.773	PhosphoSitePlus	CCLE	10.658	Down-regulation
Atypical_PIKK_ATR_ATR_ST	P35568	IRS1	Q13535	ATR	S277	S273L	273	Missense	distal	-4	no	14.052	13.178	EPSD	CCLE	10.658	Down-regulation
Atypical_PIKK_ATR_ATR_ST	P35568	IRS1	Q13535	ATR	S295	R302Q	302	Missense	distal	7	no	15.361	15.160	EPSD	CCLE	10.658	Down-regulation
Atypical_PIKK_ATR_ATR_ST	P35568	IRS1	Q13535	ATR	S315	A314D	314	Missense	proximal	-1	no	10.769	10.679	EPSD	CCLE	10.658	Down-regulation
Atypical_PIKK_ATR_ATR_ST	P35568	IRS1	Q13535	ATR	T397	T403P	403	Missense	distal	6	no	10.745	10.494	EPSD	CCLE	10.658	Loss
Atypical_PIKK_ATR_ATR_ST	P35568	IRS1	Q13535	ATR	S741	S747A	747	Missense	distal	6	no	10.880	10.554	EPSD	CCLE	10.658	Loss
Atypical_PIKK_ATR_ATR_ST	P35568	IRS1	Q13535	ATR	S741	V738M	738	Missense	distal	-3	no	10.880	10.455	EPSD	CCLE	10.658	Loss
Atypical_PIKK_ATR_ATR_ST	P49736	MCM2	Q13535	ATR	S229	V232M	232	Missense	distal	3	no	13.304	12.513	EPSD	CCLE	10.658	Down-regulation
Atypical_PIKK_ATR_ATR_ST	P49736	MCM2	Q13535	ATR	S466	T465I	465	Missense	proximal	-1	no	10.579	10.805	EPSD	CCLE	10.658	Gain
Atypical_PIKK_ATR_ATR_ST	P49736	MCM2	Q13535	ATR	T805	E800G	800	Missense	distal	-5	no	13.074	13.174	EPSD	CCLE	10.658	Up-regulation
Atypical_PIKK_ATR_ATR_ST	O15360	FANCA	Q13535	ATR	S850	Q851H	851	Missense	proximal	1	no	12.143	-5.375	EPSD	CCLE	10.658	Loss
Atypical_PIKK_ATR_ATR_ST	Q9UER7	DAXX	Q13535	ATR	S33	P29L	29	Missense	distal	-4	no	11.686	10.486	EPSD	CCLE	10.658	Loss
Atypical_PIKK_ATR_ATR_ST	Q9UER7	DAXX	Q13535	ATR	S33	P29S	29	Missense	distal	-4	no	11.686	11.361	EPSD	CCLE	10.658	Down-regulation
Atypical_PIKK_ATR_ATR_ST	Q9UER7	DAXX	Q13535	ATR	S50	K56T	56	Missense	distal	6	no	10.734	10.801	EPSD	CCLE	10.658	Up-regulation
Atypical_PIKK_ATR_ATR_ST	Q9UER7	DAXX	Q13535	ATR	S51	K56T	56	Missense	distal	5	no	11.875	11.879	EPSD	CCLE	10.658	Up-regulation
Atypical_PIKK_ATR_ATR_ST	Q9UER7	DAXX	Q13535	ATR	T151	P155T	155	Missense	distal	4	no	11.622	11.587	EPSD	CCLE	10.658	Down-regulation
Atypical_PIKK_ATR_ATR_ST	Q9UER7	DAXX	Q13535	ATR	S152	P155T	155	Missense	distal	3	no	10.953	10.668	EPSD	CCLE	10.658	Down-regulation
Atypical_PIKK_ATR_ATR_ST	Q9UER7	DAXX	Q13535	ATR	S424	M422V	422	Missense	proximal	-2	no	17.001	16.888	PhosphoSitePlus	CCLE	10.658	Down-regulation
Atypical_PIKK_ATR_ATR_ST	Q9UER7	DAXX	Q13535	ATR	S688	S683Y	683	Missense	distal	-5	no	11.222	11.549	EPSD	CCLE	10.658	Up-regulation
Atypical_PIKK_ATR_ATR_ST	Q9UER7	DAXX	Q13535	ATR	S707	P701S	701	Missense	distal	-6	no	10.780	10.735	EPSD	CCLE	10.658	Down-regulation
Atypical_PIKK_ATR_ATR_ST	Q03164	KMT2A	Q13535	ATR	S202	E203D	203	Missense	proximal	1	no	11.115	11.622	EPSD	CCLE	10.658	Up-regulation
Atypical_PIKK_ATR_ATR_ST	Q03164	KMT2A	Q13535	ATR	S1107	K1113T	1113	Missense	distal	6	no	14.530	14.597	EPSD	CCLE	10.658	Up-regulation
Atypical_PIKK_ATR_ATR_ST	Q03164	KMT2A	Q13535	ATR	S1299	S1295G	1295	Missense	distal	-4	no	15.557	15.040	EPSD	CCLE	10.658	Down-regulation
Atypical_PIKK_ATR_ATR_ST	Q03164	KMT2A	Q13535	ATR	S2255	S2255G	2255	Missense	central	0	yes	11.494	0.000	EPSD	CCLE	10.658	Loss
Atypical_PIKK_ATR_ATR_ST	Q03164	KMT2A	Q13535	ATR	S2533	P2526H	2526	Missense	distal	-7	no	12.191	12.168	EPSD	CCLE	10.658	Down-regulation
Atypical_PIKK_ATR_ATR_ST	Q02952	AKAP12	Q13535	ATR	S11	S6A	6	Missense	distal	-5	no	10.777	10.873	EPSD	CCLE	10.658	Up-regulation
Atypical_PIKK_ATR_ATR_ST	Q02952	AKAP12	Q13535	ATR	S11	Q14P	14	Missense	distal	3	no	10.777	11.144	EPSD	CCLE	10.658	Up-regulation
Atypical_PIKK_ATR_ATR_ST	Q02952	AKAP12	Q13535	ATR	T21	Q14P	14	Missense	distal	-7	no	13.424	13.467	EPSD	CCLE	10.658	Up-regulation
Atypical_PIKK_ATR_ATR_ST	Q02952	AKAP12	Q13535	ATR	S96	E100K	100	Missense	distal	4	no	14.602	14.713	EPSD	CCLE	10.658	Up-regulation
Atypical_PIKK_ATR_ATR_ST	Q02952	AKAP12	Q13535	ATR	S388	S392P	392	Missense	distal	4	no	13.618	13.704	EPSD	CCLE	10.658	Up-regulation
Atypical_PIKK_ATR_ATR_ST	Q02952	AKAP12	Q13535	ATR	T548	S554F	554	Missense	distal	6	no	12.896	12.737	EPSD	CCLE	10.658	Down-regulation
Atypical_PIKK_ATR_ATR_ST	Q02952	AKAP12	Q13535	ATR	S554	S554F	554	Missense	central	0	yes	12.675	0.000	EPSD	CCLE	10.658	Loss
Atypical_PIKK_ATR_ATR_ST	Q02952	AKAP12	Q13535	ATR	S557	S554F	554	Missense	distal	-3	no	14.036	14.895	EPSD	CCLE	10.658	Up-regulation
Atypical_PIKK_ATR_ATR_ST	Q7Z6Z7	HUWE1	Q13535	ATR	S636	Y639S	639	Missense	distal	3	no	11.656	12.573	EPSD	CCLE	10.658	Up-regulation
Atypical_PIKK_ATR_ATR_ST	Q7Z6Z7	HUWE1	Q13535	ATR	S718	P715S	715	Missense	distal	-3	no	11.153	10.877	EPSD	CCLE	10.658	Down-regulation
Atypical_PIKK_ATR_ATR_ST	Q7Z6Z7	HUWE1	Q13535	ATR	S740	T744A	744	Missense	distal	4	no	11.206	11.457	EPSD	CCLE	10.658	Up-regulation
Atypical_PIKK_ATR_ATR_ST	Q7Z6Z7	HUWE1	Q13535	ATR	T744	T744A	744	Missense	central	0	yes	13.605	0.000	EPSD	CCLE	10.658	Loss
Atypical_PIKK_ATR_ATR_ST	Q7Z6Z7	HUWE1	Q13535	ATR	S990	G987E	987	Missense	distal	-3	no	10.548	10.707	EPSD	CCLE	10.658	Gain
Atypical_PIKK_ATR_ATR_ST	Q7Z6Z7	HUWE1	Q13535	ATR	S1218	N1211Y	1211	Missense	distal	-7	no	11.806	11.767	EPSD	CCLE	10.658	Down-regulation
Atypical_PIKK_ATR_ATR_ST	Q7Z6Z7	HUWE1	Q13535	ATR	S2850	T2846M	2846	Missense	distal	-4	no	13.939	13.807	EPSD	CCLE	10.658	Down-regulation
Atypical_PIKK_ATR_ATR_ST	Q7Z6Z7	HUWE1	Q13535	ATR	T2889	P2895L	2895	Missense	distal	6	no	11.412	11.485	EPSD	CCLE	10.658	Up-regulation
Atypical_PIKK_ATR_ATR_ST	Q7Z6Z7	HUWE1	Q13535	ATR	S2922	E2915G	2915	Missense	distal	-7	no	10.847	10.769	EPSD	CCLE	10.658	Down-regulation
Atypical_PIKK_ATR_ATR_ST	Q7Z6Z7	HUWE1	Q13535	ATR	S2963	L2964F	2964	Missense	proximal	1	no	10.956	9.705	EPSD	CCLE	10.658	Loss
Atypical_PIKK_ATR_ATR_ST	Q7Z6Z7	HUWE1	Q13535	ATR	S3377	Q3378L	3378	Missense	proximal	1	no	12.196	6.762	EPSD	CCLE	10.658	Loss
Atypical_PIKK_ATR_ATR_ST	Q9NZN8	CNOT2	Q13535	ATR	S69	L75V	75	Missense	distal	6	no	11.982	12.094	EPSD	CCLE	10.658	Up-regulation
Atypical_PIKK_ATR_ATR_ST	Q9NZN8	CNOT2	Q13535	ATR	S190	R183Q	183	Missense	distal	-7	no	12.653	12.685	EPSD	CCLE	10.658	Up-regulation
Atypical_PIKK_ATR_ATR_ST	Q9NZN8	CNOT2	Q13535	ATR	S270	T263I	263	Missense	distal	-7	no	13.291	13.231	EPSD	CCLE	10.658	Down-regulation
Atypical_PIKK_ATR_ATR_ST	Q9NZN8	CNOT2	Q13535	ATR	S270	I275V	275	Missense	distal	5	no	13.291	13.280	EPSD	CCLE	10.658	Down-regulation
Atypical_PIKK_ATR_ATR_ST	Q9UH99	SUN2	Q13535	ATR	S381	A386V	386	Missense	distal	5	no	13.945	13.936	EPSD	CCLE	10.658	Down-regulation
Atypical_PIKK_ATR_ATR_ST	Q8IZL8	PELP1	Q13535	ATR	S251	G253C	253	Missense	proximal	2	no	12.188	9.565	EPSD	CCLE	10.658	Loss
Atypical_PIKK_ATR_ATR_ST	O94880	PHF14	Q13535	ATR	S39	G45A	45	Missense	distal	6	no	10.900	10.816	EPSD	CCLE	10.658	Down-regulation
Atypical_PIKK_ATR_ATR_ST	O94880	PHF14	Q13535	ATR	S196	V195M	195	Missense	proximal	-1	no	10.801	10.951	EPSD	CCLE	10.658	Up-regulation
Atypical_PIKK_ATR_ATR_ST	O94880	PHF14	Q13535	ATR	S601	N597K	597	Missense	distal	-4	no	12.380	12.761	EPSD	CCLE	10.658	Up-regulation
Atypical_PIKK_ATR_ATR_ST	Q8N4S0	CCDC82	Q13535	ATR	S320	K316N	316	Missense	distal	-4	no	13.838	13.458	EPSD	CCLE	10.658	Down-regulation
Atypical_PIKK_ATR_ATR_ST	Q14676	MDC1	Q13535	ATR	T157	P159L	159	Missense	proximal	2	no	14.762	13.480	EPSD	CCLE	10.658	Down-regulation
Atypical_PIKK_ATR_ATR_ST	Q14676	MDC1	Q13535	ATR	T157	Q158L	158	Missense	proximal	1	no	14.762	9.328	EPSD	CCLE	10.658	Loss
Atypical_PIKK_ATR_ATR_ST	Q14676	MDC1	Q13535	ATR	S202	E195K	195	Missense	distal	-7	no	11.539	11.522	EPSD	CCLE	10.658	Down-regulation
Atypical_PIKK_ATR_ATR_ST	Q14676	MDC1	Q13535	ATR	S218	T220R	220	Missense	proximal	2	no	13.752	13.869	EPSD	CCLE	10.658	Up-regulation
Atypical_PIKK_ATR_ATR_ST	Q14676	MDC1	Q13535	ATR	S394	M398V	398	Missense	distal	4	no	16.729	17.336	EPSD	CCLE	10.658	Up-regulation
Atypical_PIKK_ATR_ATR_ST	Q14676	MDC1	Q13535	ATR	S422	E421D	421	Missense	proximal	-1	no	14.280	14.325	EPSD	CCLE	10.658	Up-regulation
Atypical_PIKK_ATR_ATR_ST	Q14676	MDC1	Q13535	ATR	S874	E879G	879	Missense	distal	5	no	11.030	11.040	EPSD	CCLE	10.658	Up-regulation
Atypical_PIKK_ATR_ATR_ST	Q14676	MDC1	Q13535	ATR	T946	K939R	939	Missense	distal	-7	no	13.763	13.703	EPSD	CCLE	10.658	Down-regulation
Atypical_PIKK_ATR_ATR_ST	Q14676	MDC1	Q13535	ATR	S988	R993M	993	Missense	distal	5	no	12.254	12.252	EPSD	CCLE	10.658	Down-regulation
Atypical_PIKK_ATR_ATR_ST	Q14676	MDC1	Q13535	ATR	S988	S981T	981	Missense	distal	-7	no	12.254	12.196	EPSD	CCLE	10.658	Down-regulation
Atypical_PIKK_ATR_ATR_ST	Q14676	MDC1	Q13535	ATR	S1143	S1148N	1148	Missense	distal	5	no	14.595	14.600	EPSD	CCLE	10.658	Up-regulation
Atypical_PIKK_ATR_ATR_ST	Q14676	MDC1	Q13535	ATR	S1153	S1148N	1148	Missense	distal	-5	no	10.884	11.026	EPSD	CCLE	10.658	Up-regulation
Atypical_PIKK_ATR_ATR_ST	Q14676	MDC1	Q13535	ATR	S1430	P1426S	1426	Missense	distal	-4	no	13.048	12.723	EPSD	CCLE	10.658	Down-regulation
Atypical_PIKK_ATR_ATR_ST	Q14676	MDC1	Q13535	ATR	T1433	P1426S	1426	Missense	distal	-7	no	10.879	10.851	EPSD	CCLE	10.658	Down-regulation
Atypical_PIKK_ATR_ATR_ST	Q14676	MDC1	Q13535	ATR	T1781	Q1787H	1787	Missense	distal	6	no	12.451	12.257	EPSD	CCLE	10.658	Down-regulation
Atypical_PIKK_ATR_ATR_ST	Q14676	MDC1	Q13535	ATR	S1786	Q1787H	1787	Missense	proximal	1	no	11.649	-5.869	EPSD	CCLE	10.658	Loss
Atypical_PIKK_ATR_ATR_ST	Q6PGQ7	BORA	Q13535	ATR	S303	S308P	308	Missense	distal	5	no	10.895	10.906	EPSD	CCLE	10.658	Up-regulation
Atypical_PIKK_ATR_ATR_ST	Q6PGQ7	BORA	Q13535	ATR	T306	S308P	308	Missense	proximal	2	no	10.877	11.193	EPSD	CCLE	10.658	Up-regulation
Atypical_PIKK_ATR_ATR_ST	Q6PGQ7	BORA	Q13535	ATR	S308	S308P	308	Missense	central	0	yes	11.814	0.000	EPSD	CCLE	10.658	Loss
Atypical_PIKK_ATR_ATR_ST	O00213	APBB1	Q13535	ATR	S322	M327I	327	Missense	distal	5	no	13.484	13.488	EPSD	CCLE	10.658	Up-regulation
Atypical_PIKK_ATR_ATR_ST	O00213	APBB1	Q13535	ATR	S322	D323H	323	Missense	proximal	1	no	13.484	1.381	EPSD	CCLE	10.658	Loss
Atypical_PIKK_ATR_ATR_ST	Q8TAQ2	SMARCC2	Q13535	ATR	S347	V349I	349	Missense	proximal	2	no	12.264	10.954	EPSD	CCLE	10.658	Down-regulation
Atypical_PIKK_ATR_ATR_ST	Q8TAQ2	SMARCC2	Q13535	ATR	S347	D344G	344	Missense	distal	-3	no	12.264	11.513	EPSD	CCLE	10.658	Down-regulation
Atypical_PIKK_ATR_ATR_ST	Q8N163	CCAR2	Q13535	ATR	T454	P453S	453	Missense	proximal	-1	no	16.955	16.740	PhosphoSitePlus	CCLE	10.658	Down-regulation
Atypical_PIKK_ATR_ATR_ST	Q8N163	CCAR2	Q13535	ATR	T489	T493M	493	Missense	distal	4	no	12.293	11.797	EPSD	CCLE	10.658	Down-regulation
Atypical_PIKK_ATR_ATR_ST	O75717	WDHD1	Q13535	ATR	S1090	D1088H	1088	Missense	proximal	-2	no	10.801	10.373	EPSD	CCLE	10.658	Loss
Atypical_PIKK_ATR_ATR_ST	P49006	MARCKSL1	Q13535	ATR	S22	G20R	20	Missense	proximal	-2	no	12.778	12.874	EPSD	CCLE	10.658	Up-regulation
Atypical_PIKK_ATR_ATR_ST	P49006	MARCKSL1	Q13535	ATR	S71	G73E	73	Missense	proximal	2	no	16.420	16.550	PhosphoSitePlus	CCLE	10.658	Up-regulation
Atypical_PIKK_ATR_ATR_ST	P49006	MARCKSL1	Q13535	ATR	T85	P81A	81	Missense	distal	-4	no	11.224	11.420	EPSD	CCLE	10.658	Up-regulation
Atypical_PIKK_ATR_ATR_ST	P49006	MARCKSL1	Q13535	ATR	T148	A147T	147	Missense	proximal	-1	no	10.983	10.753	EPSD	CCLE	10.658	Down-regulation
Atypical_PIKK_ATR_ATR_ST	P49006	MARCKSL1	Q13535	ATR	S151	A147T	147	Missense	distal	-4	no	16.276	15.669	EPSD	CCLE	10.658	Down-regulation
TK_Abl_ABL2_Y	P04040	CAT	P42684	ABL2	Y231	Y231D	231	Missense	central	0	yes	36.242	0.000	PhosphoSitePlus;EPSD	CCLE	19.113	Loss
TK_Abl_ABL2_Y	P42684	ABL2	P42684	ABL2	Y439	A445G	445	Missense	distal	6	no	33.502	33.503	EPSD;PhosphoSitePlus	CCLE	19.113	Up-regulation
TK_Abl_ABL2_Y	P42684	ABL2	P42684	ABL2	Y683	G687A	687	Missense	distal	4	no	36.266	36.640	EPSD	CCLE	19.113	Up-regulation
TK_Abl_ABL2_Y	P46108	CRK	P42684	ABL2	Y239	P237S	237	Missense	proximal	-2	no	22.449	22.642	EPSD	CCLE	19.113	Up-regulation
TK_Abl_ABL2_Y	P10636	MAPT	P42684	ABL2	Y514	R511H	511	Missense	distal	-3	no	39.019	39.057	EPSD	CCLE	19.113	Up-regulation
TK_Abl_ABL2_Y	P10636	MAPT	P42684	ABL2	Y514	G518S	518	Missense	distal	4	no	39.019	39.622	EPSD	CCLE	19.113	Up-regulation
TK_Abl_ABL2_Y	P10636	MAPT	P42684	ABL2	Y627	D631E	631	Missense	distal	4	no	31.212	31.274	EPSD	CCLE	19.113	Up-regulation
TK_Abl_ABL2_Y	P10636	MAPT	P42684	ABL2	Y711	G706V	706	Missense	distal	-5	no	32.075	28.104	EPSD	CCLE	19.113	Down-regulation
TK_Abl_ABL2_Y	P10636	MAPT	P42684	ABL2	Y711	S717C	717	Missense	distal	6	no	32.075	31.611	EPSD	CCLE	19.113	Down-regulation
TK_Abl_ABL2_Y	O14818	PSMA7	P42684	ABL2	Y153	Y153C	153	Missense	central	0	yes	35.748	0.000	PhosphoSitePlus	CCLE	19.113	Loss
TK_Abl_ABL2_Y	P17931	LGALS3	P42684	ABL2	Y107	P106S	106	Missense	proximal	-1	no	36.281	30.751	EPSD	CCLE	19.113	Down-regulation
TK_Abl_ABL2_Y	P09619	PDGFRB	P42684	ABL2	Y581	M585I	585	Missense	distal	4	no	19.741	20.316	EPSD	CCLE	19.113	Up-regulation
TK_Abl_ABL2_Y	P09619	PDGFRB	P42684	ABL2	Y581	G576S	576	Missense	distal	-5	no	19.741	19.610	EPSD	CCLE	19.113	Down-regulation
TK_Abl_ABL2_Y	P09619	PDGFRB	P42684	ABL2	Y771	N777S	777	Missense	distal	6	no	20.077	20.396	EPSD	CCLE	19.113	Up-regulation
TK_Abl_ABL2_Y	P09619	PDGFRB	P42684	ABL2	Y970	K967E	967	Missense	distal	-3	no	28.921	28.966	EPSD	CCLE	19.113	Up-regulation
TK_Abl_ABL2_Y	P05556	ITGB1	P42684	ABL2	Y783	V787A	787	Missense	distal	4	no	26.275	27.182	PhosphoSitePlus	CCLE	19.113	Up-regulation
TK_Abl_ABL2_Y	O15304	SIVA1	P42684	ABL2	Y34	E37D	37	Missense	distal	3	no	32.693	33.300	PhosphoSitePlus	CCLE	19.113	Up-regulation
TK_Src_SrcB_HCK_Y	P00519	ABL1	P08631	HCK	Y115	P112S	112	Missense	distal	-3	no	11.227	11.927	EPSD;PhosphoSitePlus	CCLE	7.597	Up-regulation
TK_Src_SrcB_HCK_Y	P00519	ABL1	P08631	HCK	Y128	R134C	134	Missense	distal	6	no	11.768	12.799	EPSD;PhosphoSitePlus	CCLE	7.597	Up-regulation
TK_Src_SrcB_HCK_Y	P00519	ABL1	P08631	HCK	Y139	R134C	134	Missense	distal	-5	no	11.438	11.498	EPSD;PhosphoSitePlus	CCLE	7.597	Up-regulation
TK_Src_SrcB_HCK_Y	P00519	ABL1	P08631	HCK	Y139	A137T	137	Missense	proximal	-2	no	11.438	10.728	EPSD;PhosphoSitePlus	CCLE	7.597	Down-regulation
TK_Src_SrcB_HCK_Y	P00519	ABL1	P08631	HCK	Y172	A179V	179	Missense	distal	7	no	10.715	10.494	EPSD;PhosphoSitePlus	CCLE	7.597	Down-regulation
TK_Src_SrcB_HCK_Y	P00519	ABL1	P08631	HCK	Y185	A179V	179	Missense	distal	-6	no	10.695	9.793	EPSD;PhosphoSitePlus	CCLE	7.597	Down-regulation
TK_Src_SrcB_HCK_Y	P00519	ABL1	P08631	HCK	Y215	Y215H	215	Missense	central	0	yes	9.755	0.000	EPSD;PhosphoSitePlus	CCLE	7.597	Loss
TK_Src_SrcB_HCK_Y	P00519	ABL1	P08631	HCK	Y226	T224I	224	Missense	proximal	-2	no	8.852	8.820	EPSD;PhosphoSitePlus	CCLE	7.597	Down-regulation
TK_Src_SrcB_HCK_Y	Q92556	ELMO1	P08631	HCK	Y511	I517M	517	Missense	distal	6	no	10.557	10.856	EPSD;PhosphoSitePlus	CCLE	7.597	Up-regulation
TK_Src_SrcB_HCK_Y	Q13444	ADAM15	P08631	HCK	Y715	Y717C	717	Missense	proximal	2	no	11.829	11.676	PhosphoSitePlus	CCLE	7.597	Down-regulation
TK_Src_SrcB_HCK_Y	O15350	TP73	P08631	HCK	Y28	P24L	24	Missense	distal	-4	no	10.670	10.709	PhosphoSitePlus	CCLE	7.597	Up-regulation
TKL_MLK_MLK_MAP3K11_ST	Q13526	PIN1	Q16584	MAP3K11	S147	V150M	150	Missense	distal	3	no	1.655	1.682	EPSD	CCLE	1.264	Up-regulation
TKL_MLK_MLK_MAP3K11_ST	Q13526	PIN1	Q16584	MAP3K11	T152	V150M	150	Missense	proximal	-2	no	1.711	1.524	EPSD	CCLE	1.264	Down-regulation
TKL_MLK_MLK_MAP3K11_ST	Q13131	PRKAA1	Q16584	MAP3K11	S498	S494L	494	Missense	distal	-4	no	1.517	1.537	EPSD	CCLE	1.264	Up-regulation
TKL_MLK_MLK_MAP3K11_ST	Q13131	PRKAA1	Q16584	MAP3K11	S498	S494W	494	Missense	distal	-4	no	1.517	1.535	EPSD	CCLE	1.264	Up-regulation
Atypical_PDHK_PDHK_PDK3_ST	P29803	PDHA2	Q15120	PDK3	T231	G228E	228	Missense	distal	-3	no	2.638	2.537	EPSD	CCLE	1.746	Down-regulation
Atypical_PDHK_PDHK_PDK3_ST	P29803	PDHA2	Q15120	PDK3	T284	H288Y	288	Missense	distal	4	no	1.777	1.784	EPSD	CCLE	1.746	Up-regulation
Atypical_PDHK_PDHK_PDK3_ST	P29803	PDHA2	Q15120	PDK3	T284	H288R	288	Missense	distal	4	no	1.777	1.767	EPSD	CCLE	1.746	Down-regulation
Atypical_PDHK_PDHK_PDK3_ST	P29803	PDHA2	Q15120	PDK3	S291	H288Y	288	Missense	distal	-3	no	10.124	10.042	EPSD;PhosphoSitePlus	CCLE	1.746	Down-regulation
Atypical_PDHK_PDHK_PDK3_ST	P29803	PDHA2	Q15120	PDK3	S291	H288R	288	Missense	distal	-3	no	10.124	10.267	EPSD;PhosphoSitePlus	CCLE	1.746	Up-regulation
Atypical_PDHK_PDHK_PDK3_ST	P29803	PDHA2	Q15120	PDK3	S293	H288Y	288	Missense	distal	-5	no	2.409	2.227	EPSD	CCLE	1.746	Down-regulation
Atypical_PDHK_PDHK_PDK3_ST	P29803	PDHA2	Q15120	PDK3	S293	H288R	288	Missense	distal	-5	no	2.409	3.065	EPSD	CCLE	1.746	Up-regulation
AGC_DMPK_ROCK_ROCK2_ST	P19634	SLC9A1	O75116	ROCK2	S703	M696L	696	Missense	distal	-7	no	20.803	20.510	EPSD	CCLE	20.789	Loss
AGC_DMPK_ROCK_ROCK2_ST	P19634	SLC9A1	O75116	ROCK2	S766	T769N	769	Missense	distal	3	no	25.432	26.718	EPSD	CCLE	20.789	Up-regulation
AGC_DMPK_ROCK_ROCK2_ST	P56817	BACE1	O75116	ROCK2	S71	G69R	69	Missense	proximal	-2	no	20.101	27.692	EPSD	CCLE	20.789	Gain
AGC_DMPK_ROCK_ROCK2_ST	P56817	BACE1	O75116	ROCK2	S498	D492N	492	Missense	distal	-6	no	27.416	29.613	PhosphoSitePlus	CCLE	20.789	Up-regulation
AGC_DMPK_ROCK_ROCK2_ST	Q16555	DPYSL2	O75116	ROCK2	T555	P551L	551	Missense	distal	-4	no	39.349	39.031	PhosphoSitePlus	CCLE	20.789	Down-regulation
AGC_DMPK_ROCK_ROCK2_ST	O95644	NFATC1	O75116	ROCK2	S241	R235Q	235	Missense	distal	-6	no	29.014	28.159	PhosphoSitePlus	CCLE	20.789	Down-regulation
AGC_DMPK_ROCK_ROCK2_ST	O95644	NFATC1	O75116	ROCK2	S241	R243C	243	Missense	proximal	2	no	29.014	28.744	PhosphoSitePlus	CCLE	20.789	Down-regulation
AGC_DMPK_ROCK_ROCK2_ST	O95644	NFATC1	O75116	ROCK2	S241	S245I	245	Missense	distal	4	no	29.014	30.206	PhosphoSitePlus	CCLE	20.789	Up-regulation
AGC_DMPK_ROCK_ROCK2_ST	O95644	NFATC1	O75116	ROCK2	S257	N264S	264	Missense	distal	7	no	20.848	20.788	EPSD	CCLE	20.789	Loss
AGC_DMPK_ROCK_ROCK2_ST	O95644	NFATC1	O75116	ROCK2	S406	Y407C	407	Missense	proximal	1	no	22.810	22.829	EPSD	CCLE	20.789	Up-regulation
AGC_DMPK_ROCK_ROCK2_ST	O95644	NFATC1	O75116	ROCK2	S503	T498I	498	Missense	distal	-5	no	21.429	18.081	EPSD	CCLE	20.789	Loss
AGC_DMPK_ROCK_ROCK2_ST	O95644	NFATC1	O75116	ROCK2	S670	V672A	672	Missense	proximal	2	no	26.593	26.980	EPSD	CCLE	20.789	Up-regulation
AGC_DMPK_ROCK_ROCK2_ST	O95644	NFATC1	O75116	ROCK2	S670	H673R	673	Missense	distal	3	no	26.593	24.809	EPSD	CCLE	20.789	Down-regulation
AGC_DMPK_ROCK_ROCK2_ST	O95644	NFATC1	O75116	ROCK2	S670	S675G	675	Missense	distal	5	no	26.593	26.906	EPSD	CCLE	20.789	Up-regulation
AGC_DMPK_ROCK_ROCK2_ST	O95644	NFATC1	O75116	ROCK2	S772	T777P	777	Missense	distal	5	no	24.405	24.503	EPSD	CCLE	20.789	Up-regulation
AGC_DMPK_ROCK_ROCK2_ST	O95644	NFATC1	O75116	ROCK2	T912	I909M	909	Missense	distal	-3	no	16.276	25.771	EPSD	CCLE	20.789	Gain
AGC_DMPK_ROCK_ROCK2_ST	P53671	LIMK2	O75116	ROCK2	T505	N509S	509	Missense	distal	4	no	34.788	34.807	PhosphoSitePlus	CCLE	20.789	Up-regulation
AGC_DMPK_ROCK_ROCK2_ST	Q15417	CNN3	O75116	ROCK2	T170	M168I	168	Missense	proximal	-2	no	27.004	13.743	EPSD	CCLE	20.789	Loss
AGC_DMPK_ROCK_ROCK2_ST	Q15417	CNN3	O75116	ROCK2	T180	H187R	187	Missense	distal	7	no	25.595	25.460	EPSD	CCLE	20.789	Down-regulation
AGC_DMPK_ROCK_ROCK2_ST	Q15417	CNN3	O75116	ROCK2	T184	H187R	187	Missense	distal	3	no	29.220	27.437	EPSD	CCLE	20.789	Down-regulation
AGC_DMPK_ROCK_ROCK2_ST	Q96C90	PPP1R14B	O75116	ROCK2	S21	G18A	18	Missense	distal	-3	no	23.972	18.090	EPSD	CCLE	20.789	Loss
AGC_DMPK_ROCK_ROCK2_ST	P68104	EEF1A1	O75116	ROCK2	S21	T23A	23	Missense	proximal	2	no	24.313	24.495	EPSD	CCLE	20.789	Up-regulation
AGC_DMPK_ROCK_ROCK2_ST	P68104	EEF1A1	O75116	ROCK2	T22	T23A	23	Missense	proximal	1	no	20.963	21.020	EPSD	CCLE	20.789	Up-regulation
AGC_DMPK_ROCK_ROCK2_ST	P68104	EEF1A1	O75116	ROCK2	T24	T23A	23	Missense	proximal	-1	no	22.142	22.708	EPSD	CCLE	20.789	Up-regulation
AGC_DMPK_ROCK_ROCK2_ST	P68104	EEF1A1	O75116	ROCK2	T227	S224R	224	Missense	distal	-3	no	18.640	32.544	EPSD	CCLE	20.789	Gain
AGC_DMPK_ROCK_ROCK2_ST	P68104	EEF1A1	O75116	ROCK2	S383	G390D	390	Missense	distal	7	no	27.210	26.299	EPSD	CCLE	20.789	Down-regulation
AGC_DMPK_ROCK_ROCK2_ST	P68104	EEF1A1	O75116	ROCK2	S383	K386R	386	Missense	distal	3	no	27.210	25.024	EPSD	CCLE	20.789	Down-regulation
AGC_DMPK_ROCK_ROCK2_ST	P68104	EEF1A1	O75116	ROCK2	T432	T432L	432	Missense	central	0	yes	35.861	0.000	PhosphoSitePlus	CCLE	20.789	Loss
AGC_DMPK_ROCK_ROCK2_ST	O14974	PPP1R12A	O75116	ROCK2	S477	S477A	477	Missense	central	0	yes	22.795	0.000	EPSD	CCLE	20.789	Loss
AGC_DMPK_ROCK_ROCK2_ST	O14974	PPP1R12A	O75116	ROCK2	S478	S477A	477	Missense	proximal	-1	no	24.684	25.012	EPSD	CCLE	20.789	Up-regulation
AGC_DMPK_ROCK_ROCK2_ST	O14974	PPP1R12A	O75116	ROCK2	S1029	S1026N	1026	Missense	distal	-3	no	22.361	18.596	EPSD	CCLE	20.789	Loss
STE_STE-Unique_MAP3K14_ST	O15111	CHUK	Q99558	MAP3K14	S123	I121M	121	Missense	proximal	-2	no	241.494	243.092	EPSD	CCLE	201.043	Up-regulation
STE_STE-Unique_MAP3K14_ST	O14920	IKBKB	Q99558	MAP3K14	S733	E729Q	729	Missense	distal	-4	no	228.964	219.189	EPSD	CCLE	201.043	Down-regulation
STE_STE-Unique_MAP3K14_ST	Q00653	NFKB2	Q99558	MAP3K14	T811	S814G	814	Missense	distal	3	no	226.871	227.164	EPSD	CCLE	201.043	Up-regulation
STE_STE-Unique_MAP3K14_ST	Q00653	NFKB2	Q99558	MAP3K14	T859	D865N	865	Missense	distal	6	no	203.269	202.362	EPSD	CCLE	201.043	Down-regulation
STE_STE-Unique_MAP3K14_ST	Q00653	NFKB2	Q99558	MAP3K14	S866	D865N	865	Missense	proximal	-1	no	356.089	340.062	EPSD;PhosphoSitePlus	CCLE	201.043	Down-regulation
STE_STE-Unique_MAP3K14_ST	Q00653	NFKB2	Q99558	MAP3K14	S866	A867V	867	Missense	proximal	1	no	356.089	361.889	EPSD;PhosphoSitePlus	CCLE	201.043	Up-regulation
STE_STE-Unique_MAP3K14_ST	Q00653	NFKB2	Q99558	MAP3K14	S870	D865N	865	Missense	distal	-5	no	372.680	349.789	PhosphoSitePlus;EPSD	CCLE	201.043	Down-regulation
STE_STE-Unique_MAP3K14_ST	Q00653	NFKB2	Q99558	MAP3K14	S870	A867V	867	Missense	distal	-3	no	372.680	372.720	PhosphoSitePlus;EPSD	CCLE	201.043	Up-regulation
AGC_RSK_RSKp70_RPS6KB1_ST	P35568	IRS1	P23443	RPS6KB1	S270	S273L	273	Missense	distal	3	no	44.958	43.258	EPSD;PhosphoSitePlus	CCLE	24.279	Down-regulation
AGC_RSK_RSKp70_RPS6KB1_ST	P35568	IRS1	P23443	RPS6KB1	S272	S273L	273	Missense	proximal	1	no	27.405	28.509	EPSD	CCLE	24.279	Up-regulation
AGC_RSK_RSKp70_RPS6KB1_ST	P35568	IRS1	P23443	RPS6KB1	T305	R304H	304	Missense	proximal	-1	no	28.306	28.324	EPSD	CCLE	24.279	Up-regulation
AGC_RSK_RSKp70_RPS6KB1_ST	P35568	IRS1	P23443	RPS6KB1	T305	R302Q	302	Missense	distal	-3	no	28.306	9.251	EPSD	CCLE	24.279	Loss
AGC_RSK_RSKp70_RPS6KB1_ST	P35568	IRS1	P23443	RPS6KB1	S307	A314D	314	Missense	distal	7	no	46.236	45.451	EPSD;PhosphoSitePlus	CCLE	24.279	Down-regulation
AGC_RSK_RSKp70_RPS6KB1_ST	P35568	IRS1	P23443	RPS6KB1	S307	R304H	304	Missense	distal	-3	no	46.236	42.747	EPSD;PhosphoSitePlus	CCLE	24.279	Down-regulation
AGC_RSK_RSKp70_RPS6KB1_ST	P35568	IRS1	P23443	RPS6KB1	S307	R302Q	302	Missense	distal	-5	no	46.236	34.261	EPSD;PhosphoSitePlus	CCLE	24.279	Down-regulation
AGC_RSK_RSKp70_RPS6KB1_ST	P35568	IRS1	P23443	RPS6KB1	T309	A314D	314	Missense	distal	5	no	25.015	24.183	EPSD	CCLE	24.279	Loss
AGC_RSK_RSKp70_RPS6KB1_ST	P35568	IRS1	P23443	RPS6KB1	T309	R304H	304	Missense	distal	-5	no	25.015	22.160	EPSD	CCLE	24.279	Loss
AGC_RSK_RSKp70_RPS6KB1_ST	P35568	IRS1	P23443	RPS6KB1	T309	R302Q	302	Missense	distal	-7	no	25.015	25.085	EPSD	CCLE	24.279	Up-regulation
AGC_RSK_RSKp70_RPS6KB1_ST	P35568	IRS1	P23443	RPS6KB1	S312	A314D	314	Missense	proximal	2	no	35.163	34.527	EPSD	CCLE	24.279	Down-regulation
AGC_RSK_RSKp70_RPS6KB1_ST	P35568	IRS1	P23443	RPS6KB1	S372	S374Y	374	Missense	proximal	2	no	31.118	26.849	EPSD	CCLE	24.279	Down-regulation
AGC_RSK_RSKp70_RPS6KB1_ST	P35568	IRS1	P23443	RPS6KB1	S396	T403P	403	Missense	distal	7	no	26.269	26.461	EPSD	CCLE	24.279	Up-regulation
AGC_RSK_RSKp70_RPS6KB1_ST	P35568	IRS1	P23443	RPS6KB1	S398	T403P	403	Missense	distal	5	no	27.473	26.423	EPSD	CCLE	24.279	Down-regulation
AGC_RSK_RSKp70_RPS6KB1_ST	P35568	IRS1	P23443	RPS6KB1	S402	T403P	403	Missense	proximal	1	no	26.489	26.769	EPSD	CCLE	24.279	Up-regulation
AGC_RSK_RSKp70_RPS6KB1_ST	P35568	IRS1	P23443	RPS6KB1	T525	P532S	532	Missense	distal	7	no	28.631	29.105	EPSD	CCLE	24.279	Up-regulation
AGC_RSK_RSKp70_RPS6KB1_ST	P35568	IRS1	P23443	RPS6KB1	S527	P532S	532	Missense	distal	5	no	36.607	38.542	EPSD;PhosphoSitePlus	CCLE	24.279	Up-regulation
AGC_RSK_RSKp70_RPS6KB1_ST	P35568	IRS1	P23443	RPS6KB1	S741	V738M	738	Missense	distal	-3	no	15.129	24.383	EPSD	CCLE	24.279	Gain
AGC_RSK_RSKp70_RPS6KB1_ST	P35568	IRS1	P23443	RPS6KB1	S763	L767V	767	Missense	distal	4	no	29.109	28.343	EPSD	CCLE	24.279	Down-regulation
AGC_RSK_RSKp70_RPS6KB1_ST	P35568	IRS1	P23443	RPS6KB1	T793	S795Y	795	Missense	proximal	2	no	26.941	22.673	EPSD	CCLE	24.279	Loss
AGC_RSK_RSKp70_RPS6KB1_ST	P35568	IRS1	P23443	RPS6KB1	T793	L791P	791	Missense	proximal	-2	no	26.941	28.706	EPSD	CCLE	24.279	Up-regulation
AGC_RSK_RSKp70_RPS6KB1_ST	P35568	IRS1	P23443	RPS6KB1	S1101	S1105F	1105	Missense	distal	4	no	49.169	47.008	EPSD;PhosphoSitePlus	CCLE	24.279	Down-regulation
AGC_RSK_RSKp70_RPS6KB1_ST	P35568	IRS1	P23443	RPS6KB1	T1103	S1105F	1105	Missense	proximal	2	no	30.220	25.022	EPSD	CCLE	24.279	Down-regulation
AGC_RSK_RSKp70_RPS6KB1_ST	P35568	IRS1	P23443	RPS6KB1	S1105	S1105F	1105	Missense	central	0	yes	32.740	0.000	EPSD	CCLE	24.279	Loss
AGC_RSK_RSKp70_RPS6KB1_ST	P35568	IRS1	P23443	RPS6KB1	S1106	S1105F	1105	Missense	proximal	-1	no	27.271	27.390	EPSD	CCLE	24.279	Up-regulation
AGC_RSK_RSKp70_RPS6KB1_ST	P35568	IRS1	P23443	RPS6KB1	S1143	E1136K	1136	Missense	distal	-7	no	34.193	34.295	EPSD	CCLE	24.279	Up-regulation
AGC_RSK_RSKp70_RPS6KB1_ST	Q06787	FMR1	P23443	RPS6KB1	S460	T463A	463	Missense	distal	3	no	28.019	27.416	EPSD	CCLE	24.279	Down-regulation
AGC_RSK_RSKp70_RPS6KB1_ST	Q9UN36	NDRG2	P23443	RPS6KB1	T330	A336S	336	Missense	distal	6	no	23.763	24.883	EPSD	CCLE	24.279	Gain
AGC_RSK_RSKp70_RPS6KB1_ST	Q9UN36	NDRG2	P23443	RPS6KB1	S332	A336S	336	Missense	distal	4	no	41.835	42.338	EPSD;PhosphoSitePlus	CCLE	24.279	Up-regulation
AGC_RSK_RSKp70_RPS6KB1_ST	Q9UN36	NDRG2	P23443	RPS6KB1	S344	R347C	347	Missense	distal	3	no	27.128	25.457	EPSD	CCLE	24.279	Down-regulation
AGC_RSK_RSKp70_RPS6KB1_ST	Q9UN36	NDRG2	P23443	RPS6KB1	S346	R347C	347	Missense	proximal	1	no	30.746	31.693	EPSD	CCLE	24.279	Up-regulation
AGC_RSK_RSKp70_RPS6KB1_ST	Q9UN36	NDRG2	P23443	RPS6KB1	T348	R347C	347	Missense	proximal	-1	no	34.565	34.638	EPSD	CCLE	24.279	Up-regulation
AGC_RSK_RSKp70_RPS6KB1_ST	Q9UN36	NDRG2	P23443	RPS6KB1	S350	R347C	347	Missense	distal	-3	no	38.747	29.198	PhosphoSitePlus;EPSD	CCLE	24.279	Down-regulation
AGC_RSK_RSKp70_RPS6KB1_ST	P10636	MAPT	P23443	RPS6KB1	T69	A66V	66	Missense	distal	-3	no	25.024	20.191	EPSD	CCLE	24.279	Loss
AGC_RSK_RSKp70_RPS6KB1_ST	P10636	MAPT	P23443	RPS6KB1	S171	P170F	170	Missense	proximal	-1	no	32.927	32.950	EPSD	CCLE	24.279	Up-regulation
AGC_RSK_RSKp70_RPS6KB1_ST	P10636	MAPT	P23443	RPS6KB1	S171	G174A	174	Missense	distal	3	no	32.927	34.473	EPSD	CCLE	24.279	Up-regulation
AGC_RSK_RSKp70_RPS6KB1_ST	P10636	MAPT	P23443	RPS6KB1	S214	D221Y	221	Missense	distal	7	no	27.785	28.184	PhosphoSitePlus;EPSD	CCLE	24.279	Up-regulation
AGC_RSK_RSKp70_RPS6KB1_ST	P10636	MAPT	P23443	RPS6KB1	S232	P234S	234	Missense	proximal	2	no	23.673	26.026	EPSD	CCLE	24.279	Gain
AGC_RSK_RSKp70_RPS6KB1_ST	P10636	MAPT	P23443	RPS6KB1	S447	V442I	442	Missense	distal	-5	no	29.223	26.836	EPSD	CCLE	24.279	Down-regulation
AGC_RSK_RSKp70_RPS6KB1_ST	P10636	MAPT	P23443	RPS6KB1	S512	R511H	511	Missense	proximal	-1	no	24.496	24.513	EPSD	CCLE	24.279	Up-regulation
AGC_RSK_RSKp70_RPS6KB1_ST	P10636	MAPT	P23443	RPS6KB1	S512	G518S	518	Missense	distal	6	no	24.496	24.330	EPSD	CCLE	24.279	Down-regulation
AGC_RSK_RSKp70_RPS6KB1_ST	P10636	MAPT	P23443	RPS6KB1	S516	R511H	511	Missense	distal	-5	no	24.626	21.771	EPSD	CCLE	24.279	Loss
AGC_RSK_RSKp70_RPS6KB1_ST	P10636	MAPT	P23443	RPS6KB1	S516	G518S	518	Missense	proximal	2	no	24.626	26.435	EPSD	CCLE	24.279	Up-regulation
AGC_RSK_RSKp70_RPS6KB1_ST	P10636	MAPT	P23443	RPS6KB1	S519	G518S	518	Missense	proximal	-1	no	30.096	30.011	EPSD	CCLE	24.279	Down-regulation
AGC_RSK_RSKp70_RPS6KB1_ST	P10636	MAPT	P23443	RPS6KB1	S519	R526L	526	Missense	distal	7	no	30.096	30.113	EPSD	CCLE	24.279	Up-regulation
AGC_RSK_RSKp70_RPS6KB1_ST	P10636	MAPT	P23443	RPS6KB1	T522	G518S	518	Missense	distal	-4	no	25.064	28.111	EPSD	CCLE	24.279	Up-regulation
AGC_RSK_RSKp70_RPS6KB1_ST	P10636	MAPT	P23443	RPS6KB1	T522	R526L	526	Missense	distal	4	no	25.064	25.818	EPSD	CCLE	24.279	Up-regulation
AGC_RSK_RSKp70_RPS6KB1_ST	P10636	MAPT	P23443	RPS6KB1	S525	G518S	518	Missense	distal	-7	no	28.457	28.280	EPSD	CCLE	24.279	Down-regulation
AGC_RSK_RSKp70_RPS6KB1_ST	P10636	MAPT	P23443	RPS6KB1	S525	R526L	526	Missense	proximal	1	no	28.457	28.771	EPSD	CCLE	24.279	Up-regulation
AGC_RSK_RSKp70_RPS6KB1_ST	P10636	MAPT	P23443	RPS6KB1	T529	R526L	526	Missense	distal	-3	no	35.856	26.189	EPSD	CCLE	24.279	Down-regulation
AGC_RSK_RSKp70_RPS6KB1_ST	P10636	MAPT	P23443	RPS6KB1	S531	R526L	526	Missense	distal	-5	no	44.735	36.110	EPSD	CCLE	24.279	Down-regulation
AGC_RSK_RSKp70_RPS6KB1_ST	P10636	MAPT	P23443	RPS6KB1	S552	R559H	559	Missense	distal	7	no	28.992	28.879	EPSD	CCLE	24.279	Down-regulation
AGC_RSK_RSKp70_RPS6KB1_ST	P10636	MAPT	P23443	RPS6KB1	S554	R559H	559	Missense	distal	5	no	25.150	25.451	EPSD	CCLE	24.279	Up-regulation
AGC_RSK_RSKp70_RPS6KB1_ST	P10636	MAPT	P23443	RPS6KB1	S555	R559H	559	Missense	distal	4	no	25.056	25.119	EPSD	CCLE	24.279	Up-regulation
AGC_RSK_RSKp70_RPS6KB1_ST	P10636	MAPT	P23443	RPS6KB1	S579	K574N	574	Missense	distal	-5	no	35.263	34.406	EPSD	CCLE	24.279	Down-regulation
AGC_RSK_RSKp70_RPS6KB1_ST	P10636	MAPT	P23443	RPS6KB1	S721	H724R	724	Missense	distal	3	no	24.157	24.549	EPSD	CCLE	24.279	Gain
AGC_RSK_RSKp70_RPS6KB1_ST	P10636	MAPT	P23443	RPS6KB1	S729	H724R	724	Missense	distal	-5	no	26.207	29.061	EPSD	CCLE	24.279	Up-regulation
AGC_RSK_RSKp70_RPS6KB1_ST	P10636	MAPT	P23443	RPS6KB1	S739	Q741K	741	Missense	proximal	2	no	23.241	25.998	EPSD	CCLE	24.279	Gain
AGC_RSK_RSKp70_RPS6KB1_ST	Q8TB45	DEPTOR	P23443	RPS6KB1	S15	A22T	22	Missense	distal	7	no	25.281	24.929	EPSD	CCLE	24.279	Down-regulation
AGC_RSK_RSKp70_RPS6KB1_ST	Q8TB45	DEPTOR	P23443	RPS6KB1	S19	A22T	22	Missense	distal	3	no	24.189	24.792	EPSD	CCLE	24.279	Gain
AGC_RSK_RSKp70_RPS6KB1_ST	Q8TB45	DEPTOR	P23443	RPS6KB1	S258	N255S	255	Missense	distal	-3	no	25.719	25.187	EPSD	CCLE	24.279	Down-regulation
AGC_RSK_RSKp70_RPS6KB1_ST	Q8TB45	DEPTOR	P23443	RPS6KB1	S260	N255S	255	Missense	distal	-5	no	24.273	25.383	EPSD	CCLE	24.279	Gain
AGC_RSK_RSKp70_RPS6KB1_ST	Q8TB45	DEPTOR	P23443	RPS6KB1	S286	S292R	292	Missense	distal	6	no	40.358	39.780	EPSD;PhosphoSitePlus	CCLE	24.279	Down-regulation
AGC_RSK_RSKp70_RPS6KB1_ST	Q8TB45	DEPTOR	P23443	RPS6KB1	S286	S293N	293	Missense	distal	7	no	40.358	39.578	EPSD;PhosphoSitePlus	CCLE	24.279	Down-regulation
AGC_RSK_RSKp70_RPS6KB1_ST	Q8TB45	DEPTOR	P23443	RPS6KB1	S287	S292R	292	Missense	distal	5	no	36.376	34.478	PhosphoSitePlus;EPSD	CCLE	24.279	Down-regulation
AGC_RSK_RSKp70_RPS6KB1_ST	Q8TB45	DEPTOR	P23443	RPS6KB1	S287	S293N	293	Missense	distal	6	no	36.376	34.919	PhosphoSitePlus;EPSD	CCLE	24.279	Down-regulation
AGC_RSK_RSKp70_RPS6KB1_ST	Q8TB45	DEPTOR	P23443	RPS6KB1	S291	S292R	292	Missense	proximal	1	no	38.136	38.926	EPSD;PhosphoSitePlus	CCLE	24.279	Up-regulation
AGC_RSK_RSKp70_RPS6KB1_ST	Q8TB45	DEPTOR	P23443	RPS6KB1	S291	S293N	293	Missense	proximal	2	no	38.136	34.633	EPSD;PhosphoSitePlus	CCLE	24.279	Down-regulation
AGC_RSK_RSKp70_RPS6KB1_ST	Q8TB45	DEPTOR	P23443	RPS6KB1	T295	S292R	292	Missense	distal	-3	no	17.800	27.283	EPSD	CCLE	24.279	Gain
AGC_RSK_RSKp70_RPS6KB1_ST	O00418	EEF2K	P23443	RPS6KB1	S366	S359C	359	Missense	distal	-7	no	37.526	37.690	PhosphoSitePlus	CCLE	24.279	Up-regulation
AGC_RSK_RSKp70_RPS6KB1_ST	O00418	EEF2K	P23443	RPS6KB1	S404	S404N	404	Missense	central	0	yes	28.363	0.000	EPSD	CCLE	24.279	Loss
AGC_RSK_RSKp70_RPS6KB1_ST	O00418	EEF2K	P23443	RPS6KB1	S462	R457Q	457	Missense	distal	-5	no	31.229	19.254	EPSD	CCLE	24.279	Loss
AGC_RSK_RSKp70_RPS6KB1_ST	O00418	EEF2K	P23443	RPS6KB1	S462	E458G	458	Missense	distal	-4	no	31.229	29.685	EPSD	CCLE	24.279	Down-regulation
AGC_RSK_RSKp70_RPS6KB1_ST	P03372	ESR1	P23443	RPS6KB1	S236	A239D	239	Missense	distal	3	no	28.484	29.576	EPSD	CCLE	24.279	Up-regulation
AGC_RSK_RSKp70_RPS6KB1_ST	O94763	URI1	P23443	RPS6KB1	T350	N353I	353	Missense	distal	3	no	37.604	36.631	EPSD	CCLE	24.279	Down-regulation
AGC_RSK_RSKp70_RPS6KB1_ST	O94763	URI1	P23443	RPS6KB1	S359	N353I	353	Missense	distal	-6	no	25.048	25.082	EPSD	CCLE	24.279	Up-regulation
AGC_RSK_RSKp70_RPS6KB1_ST	Q09161	NCBP1	P23443	RPS6KB1	T21	H16R	16	Missense	distal	-5	no	31.913	34.768	EPSD;PhosphoSitePlus	CCLE	24.279	Up-regulation
AGC_RSK_RSKp70_RPS6KB1_ST	Q09161	NCBP1	P23443	RPS6KB1	S22	H16R	16	Missense	distal	-6	no	31.919	31.905	PhosphoSitePlus;EPSD	CCLE	24.279	Down-regulation
AGC_RSK_RSKp70_RPS6KB1_ST	Q09161	NCBP1	P23443	RPS6KB1	S434	S438T	438	Missense	distal	4	no	28.061	27.311	EPSD	CCLE	24.279	Down-regulation
AGC_RSK_RSKp70_RPS6KB1_ST	O60331	PIP5K1C	P23443	RPS6KB1	T69	A65V	65	Missense	distal	-4	no	26.322	25.334	EPSD	CCLE	24.279	Down-regulation
AGC_RSK_RSKp70_RPS6KB1_ST	O60331	PIP5K1C	P23443	RPS6KB1	S666	D667N	667	Missense	proximal	1	no	25.897	24.903	EPSD	CCLE	24.279	Down-regulation
AGC_RSK_RSKp70_RPS6KB1_ST	O60331	PIP5K1C	P23443	RPS6KB1	S666	P660R	660	Missense	distal	-6	no	25.897	25.853	EPSD	CCLE	24.279	Down-regulation
AGC_RSK_RSKp70_RPS6KB1_ST	P08151	GLI1	P23443	RPS6KB1	T205	P202H	202	Missense	distal	-3	no	16.542	25.674	EPSD	CCLE	24.279	Gain
AGC_RSK_RSKp70_RPS6KB1_ST	P08151	GLI1	P23443	RPS6KB1	S408	S410F	410	Missense	proximal	2	no	30.573	25.375	EPSD	CCLE	24.279	Down-regulation
AGC_RSK_RSKp70_RPS6KB1_ST	P08151	GLI1	P23443	RPS6KB1	S544	I549S	549	Missense	distal	5	no	26.742	29.832	EPSD	CCLE	24.279	Up-regulation
AGC_RSK_RSKp70_RPS6KB1_ST	P08151	GLI1	P23443	RPS6KB1	S545	I549S	549	Missense	distal	4	no	26.328	27.516	EPSD	CCLE	24.279	Up-regulation
AGC_RSK_RSKp70_RPS6KB1_ST	Q6R327	RICTOR	P23443	RPS6KB1	S21	V15I	15	Missense	distal	-6	no	34.352	34.337	EPSD	CCLE	24.279	Down-regulation
AGC_RSK_RSKp70_RPS6KB1_ST	Q6R327	RICTOR	P23443	RPS6KB1	T701	D706E	706	Missense	distal	5	no	27.589	28.759	EPSD	CCLE	24.279	Up-regulation
AGC_RSK_RSKp70_RPS6KB1_ST	Q6R327	RICTOR	P23443	RPS6KB1	S704	D706E	706	Missense	proximal	2	no	30.862	31.549	EPSD	CCLE	24.279	Up-regulation
AGC_RSK_RSKp70_RPS6KB1_ST	Q6R327	RICTOR	P23443	RPS6KB1	S1026	S1020I	1020	Missense	distal	-6	no	29.112	29.173	EPSD	CCLE	24.279	Up-regulation
AGC_RSK_RSKp70_RPS6KB1_ST	Q6R327	RICTOR	P23443	RPS6KB1	S1026	P1019Q	1019	Missense	distal	-7	no	29.112	29.013	EPSD	CCLE	24.279	Down-regulation
AGC_RSK_RSKp70_RPS6KB1_ST	Q6R327	RICTOR	P23443	RPS6KB1	S1122	K1119E	1119	Missense	distal	-3	no	26.492	23.764	EPSD	CCLE	24.279	Loss
AGC_RSK_RSKp70_RPS6KB1_ST	Q6R327	RICTOR	P23443	RPS6KB1	S1302	A1309T	1309	Missense	distal	7	no	29.044	28.692	EPSD	CCLE	24.279	Down-regulation
AGC_RSK_RSKp70_RPS6KB1_ST	Q6R327	RICTOR	P23443	RPS6KB1	S1307	A1309T	1309	Missense	proximal	2	no	24.384	26.348	EPSD	CCLE	24.279	Up-regulation
AGC_RSK_RSKp70_RPS6KB1_ST	Q6R327	RICTOR	P23443	RPS6KB1	S1344	E1349K	1349	Missense	distal	5	no	33.629	33.854	EPSD	CCLE	24.279	Up-regulation
AGC_RSK_RSKp70_RPS6KB1_ST	Q6R327	RICTOR	P23443	RPS6KB1	S1346	E1349K	1349	Missense	distal	3	no	26.466	25.692	EPSD	CCLE	24.279	Down-regulation
AGC_RSK_RSKp70_RPS6KB1_ST	Q6R327	RICTOR	P23443	RPS6KB1	S1348	E1349K	1349	Missense	proximal	1	no	28.252	26.670	EPSD	CCLE	24.279	Down-regulation
AGC_RSK_RSKp70_RPS6KB1_ST	Q6R327	RICTOR	P23443	RPS6KB1	S1588	S1587G	1587	Missense	proximal	-1	no	28.571	28.656	EPSD	CCLE	24.279	Up-regulation
AGC_RSK_RSKp70_RPS6KB1_ST	P23588	EIF4B	P23443	RPS6KB1	T205	Y211C	211	Missense	distal	6	no	33.776	34.251	EPSD	CCLE	24.279	Up-regulation
AGC_RSK_RSKp70_RPS6KB1_ST	P23588	EIF4B	P23443	RPS6KB1	S207	Y211C	211	Missense	distal	4	no	25.808	25.348	EPSD	CCLE	24.279	Down-regulation
AGC_RSK_RSKp70_RPS6KB1_ST	P23588	EIF4B	P23443	RPS6KB1	S498	Q503P	503	Missense	distal	5	no	26.499	25.800	EPSD	CCLE	24.279	Down-regulation
AGC_RSK_RSKp70_RPS6KB1_ST	P23588	EIF4B	P23443	RPS6KB1	S504	Q503P	503	Missense	proximal	-1	no	26.035	26.075	EPSD	CCLE	24.279	Up-regulation
AGC_RSK_RSKp70_RPS6KB1_ST	Q9BY77	POLDIP3	P23443	RPS6KB1	S383	E376K	376	Missense	distal	-7	no	35.954	36.055	PhosphoSitePlus;EPSD	CCLE	24.279	Up-regulation
Atypical_Alpha_ChaK_TRPM7_ST	Q96QT4	TRPM7	Q96QT4	TRPM7	S1191	S1193G	1193	Missense	proximal	2	no	4.075	4.254	EPSD;PhosphoSitePlus	CCLE	3.661	Up-regulation
Atypical_Alpha_ChaK_TRPM7_ST	Q96QT4	TRPM7	Q96QT4	TRPM7	S1193	S1193G	1193	Missense	central	0	yes	3.735	0.000	PhosphoSitePlus;EPSD	CCLE	3.661	Loss
Atypical_Alpha_ChaK_TRPM7_ST	Q96QT4	TRPM7	Q96QT4	TRPM7	S1387	G1385S	1385	Missense	proximal	-2	no	4.463	4.061	EPSD;PhosphoSitePlus	CCLE	3.661	Down-regulation
Atypical_Alpha_ChaK_TRPM7_ST	Q96QT4	TRPM7	Q96QT4	TRPM7	S1390	G1385S	1385	Missense	distal	-5	no	4.119	4.639	EPSD;PhosphoSitePlus	CCLE	3.661	Up-regulation
Atypical_Alpha_ChaK_TRPM7_ST	Q96QT4	TRPM7	Q96QT4	TRPM7	S1533	E1535G	1535	Missense	proximal	2	no	3.637	3.809	EPSD;PhosphoSitePlus	CCLE	3.661	Gain
Atypical_Alpha_ChaK_TRPM7_ST	Q96QT4	TRPM7	Q96QT4	TRPM7	T1537	E1535G	1535	Missense	proximal	-2	no	3.599	3.862	EPSD;PhosphoSitePlus	CCLE	3.661	Gain
Atypical_Alpha_ChaK_TRPM7_ST	Q96QT4	TRPM7	Q96QT4	TRPM7	S1615	G1620R	1620	Missense	distal	5	no	3.007	3.770	EPSD;PhosphoSitePlus	CCLE	3.661	Gain
Atypical_Alpha_ChaK_TRPM7_ST	O00418	EEF2K	Q96QT4	TRPM7	S366	S359C	359	Missense	distal	-7	no	4.399	4.241	EPSD	CCLE	3.661	Down-regulation
TK_Axl_MERTK_Y	P31749	AKT1	Q12866	MERTK	Y437	D439H	439	Missense	proximal	2	no	1.746	1.903	EPSD	CCLE	1.889	Gain
STE_STE20_PAKB_PAK6_ST	Q00987	MDM2	Q9NQU5	PAK6	T49	D46N	46	Missense	distal	-3	no	1.317	1.536	EPSD	CCLE	1.514	Gain
STE_STE20_PAKB_PAK6_ST	Q00987	MDM2	Q9NQU5	PAK6	S395	S400N	400	Missense	distal	5	no	1.569	1.608	EPSD	CCLE	1.514	Up-regulation
STE_STE20_PAKB_PAK6_ST	P56545	CTBP2	Q9NQU5	PAK6	T88	E93K	93	Missense	distal	5	no	1.747	1.493	EPSD	CCLE	1.514	Loss
STE_STE20_PAKB_PAK6_ST	P56545	CTBP2	Q9NQU5	PAK6	T88	Y82H	82	Missense	distal	-6	no	1.747	1.593	EPSD	CCLE	1.514	Down-regulation
STE_STE20_PAKB_PAK6_ST	Q13363	CTBP1	Q9NQU5	PAK6	T80	T82I	82	Missense	proximal	2	no	1.494	1.630	EPSD	CCLE	1.514	Gain
STE_STE20_PAKB_PAK6_ST	Q13363	CTBP1	Q9NQU5	PAK6	S298	E295K	295	Missense	distal	-3	no	2.054	2.167	EPSD	CCLE	1.514	Up-regulation
STE_STE20_PAKB_PAK6_ST	Q13363	CTBP1	Q9NQU5	PAK6	S298	H292R	292	Missense	distal	-6	no	2.054	2.201	EPSD	CCLE	1.514	Up-regulation
STE_STE20_PAKB_PAK6_ST	Q13363	CTBP1	Q9NQU5	PAK6	S406	G410S	410	Missense	distal	4	no	2.030	2.009	EPSD	CCLE	1.514	Down-regulation
STE_STE20_PAKA_PAK1_ST	P36871	PGM1	Q13153	PAK1	S134	F131L	131	Missense	distal	-3	no	20.564	19.234	EPSD	CCLE	19.028	Down-regulation
STE_STE20_PAKA_PAK1_ST	P51114	FXR1	Q13153	PAK1	S448	G451E	451	Missense	distal	3	no	23.559	21.047	EPSD	CCLE	19.028	Down-regulation
STE_STE20_PAKA_PAK1_ST	P51114	FXR1	Q13153	PAK1	S450	G451E	451	Missense	proximal	1	no	20.541	20.795	EPSD	CCLE	19.028	Up-regulation
STE_STE20_PAKA_PAK1_ST	P51114	FXR1	Q13153	PAK1	S506	T500I	500	Missense	distal	-6	no	24.627	22.579	EPSD	CCLE	19.028	Down-regulation
STE_STE20_PAKA_PAK1_ST	P51114	FXR1	Q13153	PAK1	S506	R502C	502	Missense	distal	-4	no	24.627	23.668	EPSD	CCLE	19.028	Down-regulation
STE_STE20_PAKA_PAK1_ST	P51114	FXR1	Q13153	PAK1	T557	A559G	559	Missense	proximal	2	no	21.363	21.607	EPSD	CCLE	19.028	Up-regulation
STE_STE20_PAKA_PAK1_ST	Q13153	PAK1	Q13153	PAK1	S199	E195Q	195	Missense	distal	-4	no	21.601	21.418	PhosphoSitePlus;EPSD	CCLE	19.028	Down-regulation
STE_STE20_PAKA_PAK1_ST	Q13153	PAK1	Q13153	PAK1	S199	P194L	194	Missense	distal	-5	no	21.601	21.500	PhosphoSitePlus;EPSD	CCLE	19.028	Down-regulation
STE_STE20_PAKA_PAK1_ST	Q13153	PAK1	Q13153	PAK1	S259	E255D	255	Missense	distal	-4	no	21.435	21.314	EPSD	CCLE	19.028	Down-regulation
STE_STE20_PAKA_PAK1_ST	Q13153	PAK1	Q13153	PAK1	T271	T271A	271	Missense	central	0	yes	19.302	0.000	EPSD	CCLE	19.028	Loss
STE_STE20_PAKA_PAK1_ST	Q13153	PAK1	Q13153	PAK1	S491	E488K	488	Missense	distal	-3	no	5.948	19.740	EPSD	CCLE	19.028	Gain
STE_STE20_PAKA_PAK1_ST	O15143	ARPC1B	Q13153	PAK1	T21	D19V	19	Missense	proximal	-2	no	21.594	22.370	PhosphoSitePlus	CCLE	19.028	Up-regulation
STE_STE20_PAKA_PAK1_ST	O15143	ARPC1B	Q13153	PAK1	S292	K289N	289	Missense	distal	-3	no	20.089	12.244	EPSD	CCLE	19.028	Loss
STE_STE20_PAKA_PAK1_ST	O15143	ARPC1B	Q13153	PAK1	S310	S311C	311	Missense	proximal	1	no	21.527	21.485	EPSD	CCLE	19.028	Down-regulation
STE_STE20_PAKA_PAK1_ST	O15143	ARPC1B	Q13153	PAK1	S311	S311C	311	Missense	central	0	yes	22.081	0.000	EPSD	CCLE	19.028	Loss
STE_STE20_PAKA_PAK1_ST	P19086	GNAZ	Q13153	PAK1	S16	R14W	14	Missense	proximal	-2	no	28.087	15.149	PhosphoSitePlus	CCLE	19.028	Loss
STE_STE20_PAKA_PAK1_ST	P19086	GNAZ	Q13153	PAK1	S16	S16P	16	Missense	central	0	yes	28.087	0.000	PhosphoSitePlus	CCLE	19.028	Loss
STE_STE20_PAKA_PAK1_ST	P04049	RAF1	Q13153	PAK1	S12	F17L	17	Missense	distal	5	no	23.349	23.356	EPSD	CCLE	19.028	Up-regulation
STE_STE20_PAKA_PAK1_ST	P04049	RAF1	Q13153	PAK1	S43	A42I	42	Missense	proximal	-1	no	27.696	29.871	EPSD	CCLE	19.028	Up-regulation
STE_STE20_PAKA_PAK1_ST	P04049	RAF1	Q13153	PAK1	S357	S352L	352	Missense	distal	-5	no	18.996	19.757	EPSD	CCLE	19.028	Gain
STE_STE20_PAKA_PAK1_ST	Q92934	BAD	Q13153	PAK1	S74	H73Q	73	Missense	proximal	-1	no	20.464	21.552	EPSD;PhosphoSitePlus	CCLE	19.028	Up-regulation
STE_STE20_PAKA_PAK1_ST	Q92934	BAD	Q13153	PAK1	S74	R70W	70	Missense	distal	-4	no	20.464	19.479	EPSD;PhosphoSitePlus	CCLE	19.028	Down-regulation
STE_STE20_PAKA_PAK1_ST	Q92934	BAD	Q13153	PAK1	S75	H73Q	73	Missense	proximal	-2	no	25.891	22.098	PhosphoSitePlus;EPSD	CCLE	19.028	Down-regulation
STE_STE20_PAKA_PAK1_ST	Q92934	BAD	Q13153	PAK1	S75	R70W	70	Missense	distal	-5	no	25.891	27.020	PhosphoSitePlus;EPSD	CCLE	19.028	Up-regulation
STE_STE20_PAKA_PAK1_ST	Q92974	ARHGEF2	Q13153	PAK1	S172	R168H	168	Missense	distal	-4	no	24.476	24.042	EPSD	CCLE	19.028	Down-regulation
STE_STE20_PAKA_PAK1_ST	Q92974	ARHGEF2	Q13153	PAK1	S186	E193Q	193	Missense	distal	7	no	21.191	21.119	EPSD	CCLE	19.028	Down-regulation
STE_STE20_PAKA_PAK1_ST	Q92974	ARHGEF2	Q13153	PAK1	S295	R300L	300	Missense	distal	5	no	24.588	24.601	EPSD	CCLE	19.028	Up-regulation
STE_STE20_PAKA_PAK1_ST	Q92974	ARHGEF2	Q13153	PAK1	S295	R292H	292	Missense	distal	-3	no	24.588	18.516	EPSD	CCLE	19.028	Loss
STE_STE20_PAKA_PAK1_ST	Q92974	ARHGEF2	Q13153	PAK1	T392	L396S	396	Missense	distal	4	no	19.749	18.956	EPSD	CCLE	19.028	Loss
STE_STE20_PAKA_PAK1_ST	Q92974	ARHGEF2	Q13153	PAK1	T455	A453T	453	Missense	proximal	-2	no	20.573	23.530	EPSD	CCLE	19.028	Up-regulation
STE_STE20_PAKA_PAK1_ST	Q92974	ARHGEF2	Q13153	PAK1	S645	L646P	646	Missense	proximal	1	no	19.400	19.113	EPSD	CCLE	19.028	Down-regulation
STE_STE20_PAKA_PAK1_ST	Q92974	ARHGEF2	Q13153	PAK1	S645	R642S	642	Missense	distal	-3	no	19.400	10.728	EPSD	CCLE	19.028	Loss
STE_STE20_PAKA_PAK1_ST	Q13233	MAP3K1	Q13153	PAK1	S67	Q61K	61	Missense	distal	-6	no	23.986	23.190	PhosphoSitePlus	CCLE	19.028	Down-regulation
STE_STE20_PAKA_PAK1_ST	Q13233	MAP3K1	Q13153	PAK1	S154	A160T	160	Missense	distal	6	no	20.384	20.093	EPSD	CCLE	19.028	Down-regulation
STE_STE20_PAKA_PAK1_ST	Q13233	MAP3K1	Q13153	PAK1	S292	A290V	290	Missense	proximal	-2	no	19.861	22.121	EPSD	CCLE	19.028	Up-regulation
STE_STE20_PAKA_PAK1_ST	Q99426	TBCB	Q13153	PAK1	S128	G131S	131	Missense	distal	3	no	20.192	17.448	PhosphoSitePlus;EPSD	CCLE	19.028	Loss
STE_STE20_PAKA_PAK1_ST	Q99661	KIF2C	Q13153	PAK1	S589	S592N	592	Missense	distal	3	no	18.451	20.171	EPSD	CCLE	19.028	Gain
STE_STE20_PAKA_PAK1_ST	P18669	PGAM1	Q13153	PAK1	S23	G24D	24	Missense	proximal	1	no	23.434	23.614	PhosphoSitePlus;EPSD	CCLE	19.028	Up-regulation
STE_STE20_PAKA_PAK1_ST	P18669	PGAM1	Q13153	PAK1	T146	R140C	140	Missense	distal	-6	no	19.034	15.329	EPSD	CCLE	19.028	Loss
STE_STE20_PAKA_PAK1_ST	P78545	ELF3	Q13153	PAK1	S207	R205G	205	Missense	proximal	-2	no	22.411	12.848	PhosphoSitePlus	CCLE	19.028	Loss
STE_STE20_PAKA_PAK1_ST	P46108	CRK	Q13153	PAK1	S41	Y47N	47	Missense	distal	6	no	23.881	23.422	PhosphoSitePlus	CCLE	19.028	Down-regulation
STE_STE20_PAKA_PAK1_ST	Q9Y6X9	MORC2	Q13153	PAK1	S268	Y272C	272	Missense	distal	4	no	30.125	29.586	EPSD	CCLE	19.028	Down-regulation
STE_STE20_PAKA_PAK1_ST	Q9Y6X9	MORC2	Q13153	PAK1	S281	R287C	287	Missense	distal	6	no	19.770	20.406	EPSD	CCLE	19.028	Up-regulation
STE_STE20_PAKA_PAK1_ST	Q9Y6X9	MORC2	Q13153	PAK1	S648	T650I	650	Missense	proximal	2	no	21.222	22.110	EPSD	CCLE	19.028	Up-regulation
STE_STE20_PAKA_PAK1_ST	Q9Y6X9	MORC2	Q13153	PAK1	S725	K721N	721	Missense	distal	-4	no	22.319	21.609	EPSD	CCLE	19.028	Down-regulation
STE_STE20_PAKA_PAK1_ST	Q9Y6X9	MORC2	Q13153	PAK1	S739	A741T	741	Missense	proximal	2	no	28.363	26.720	PhosphoSitePlus	CCLE	19.028	Down-regulation
STE_STE20_PAKA_PAK1_ST	Q9Y6X9	MORC2	Q13153	PAK1	S739	R738Q	738	Missense	proximal	-1	no	28.363	26.644	PhosphoSitePlus	CCLE	19.028	Down-regulation
STE_STE20_PAKA_PAK1_ST	Q9Y6X9	MORC2	Q13153	PAK1	S739	R738W	738	Missense	proximal	-1	no	28.363	24.742	PhosphoSitePlus	CCLE	19.028	Down-regulation
STE_STE20_PAKA_PAK1_ST	Q9Y6X9	MORC2	Q13153	PAK1	S773	D772N	772	Missense	proximal	-1	no	20.216	18.040	EPSD	CCLE	19.028	Loss
STE_STE20_PAKA_PAK1_ST	Q9Y6X9	MORC2	Q13153	PAK1	S773	E769K	769	Missense	distal	-4	no	20.216	20.295	EPSD	CCLE	19.028	Up-regulation
STE_STE20_PAKA_PAK1_ST	Q9Y6X9	MORC2	Q13153	PAK1	S856	K853N	853	Missense	distal	-3	no	21.359	13.514	EPSD	CCLE	19.028	Loss
STE_STE20_PAKA_PAK1_ST	Q9Y6X9	MORC2	Q13153	PAK1	S930	P924H	924	Missense	distal	-6	no	19.858	21.067	EPSD	CCLE	19.028	Up-regulation
STE_STE20_PAKA_PAK1_ST	Q14247	CTTN	Q13153	PAK1	S155	F158V	158	Missense	distal	3	no	21.265	22.141	EPSD	CCLE	19.028	Up-regulation
STE_STE20_PAKA_PAK1_ST	Q14247	CTTN	Q13153	PAK1	S156	F158V	158	Missense	proximal	2	no	20.434	21.325	EPSD	CCLE	19.028	Up-regulation
STE_STE20_PAKA_PAK1_ST	Q14247	CTTN	Q13153	PAK1	S192	G196S	196	Missense	distal	4	no	22.007	20.799	EPSD	CCLE	19.028	Down-regulation
STE_STE20_PAKA_PAK1_ST	Q14247	CTTN	Q13153	PAK1	T267	G271R	271	Missense	distal	4	no	20.260	18.448	EPSD	CCLE	19.028	Loss
STE_STE20_PAKA_PAK1_ST	P49023	PXN	Q13153	PAK1	S244	E241K	241	Missense	distal	-3	no	9.175	22.967	EPSD	CCLE	19.028	Gain
STE_STE20_PAKA_PAK1_ST	Q9Y2X7	GIT1	Q13153	PAK1	S585	G591S	591	Missense	distal	6	no	22.971	22.608	EPSD	CCLE	19.028	Down-regulation
STE_STE20_PAKA_PAK1_ST	Q9Y2X7	GIT1	Q13153	PAK1	S588	G591S	591	Missense	distal	3	no	20.441	17.697	EPSD	CCLE	19.028	Loss
STE_STE20_PAKA_PAK1_ST	Q9Y2X7	GIT1	Q13153	PAK1	S592	G591S	591	Missense	proximal	-1	no	21.563	24.551	EPSD	CCLE	19.028	Up-regulation
STE_STE20_PAKA_PAK1_ST	P53350	PLK1	Q13153	PAK1	S326	F325V	325	Missense	proximal	-1	no	24.459	21.741	EPSD	CCLE	19.028	Down-regulation
STE_STE20_PAKA_PAK1_ST	Q13352	ITGB3BP	Q13153	PAK1	S28	S21L	21	Missense	distal	-7	no	23.887	23.183	PhosphoSitePlus	CCLE	19.028	Down-regulation
STE_STE20_PAKA_PAK1_ST	P21333	FLNA	Q13153	PAK1	S440	R443S	443	Missense	distal	3	no	20.064	19.905	EPSD	CCLE	19.028	Down-regulation
STE_STE20_PAKA_PAK1_ST	P21333	FLNA	Q13153	PAK1	T1305	Q1310R	1310	Missense	distal	5	no	19.455	19.457	EPSD	CCLE	19.028	Up-regulation
STE_STE20_PAKA_PAK1_ST	P21333	FLNA	Q13153	PAK1	T1305	A1298T	1298	Missense	distal	-7	no	19.455	19.598	EPSD	CCLE	19.028	Up-regulation
STE_STE20_PAKA_PAK1_ST	P21333	FLNA	Q13153	PAK1	S2260	P2256T	2256	Missense	distal	-4	no	19.181	19.747	EPSD	CCLE	19.028	Up-regulation
STE_STE20_PAKA_PAK1_ST	O43623	SNAI2	Q13153	PAK1	S87	D93G	93	Missense	distal	6	no	21.018	21.341	EPSD	CCLE	19.028	Up-regulation
STE_STE20_PAKA_PAK1_ST	O43623	SNAI2	Q13153	PAK1	S100	D93G	93	Missense	distal	-7	no	20.384	19.707	EPSD	CCLE	19.028	Down-regulation
STE_STE20_PAKA_PAK1_ST	P52565	ARHGDIA	Q13153	PAK1	S101	S96N	96	Missense	distal	-5	no	23.937	24.573	EPSD;PhosphoSitePlus	CCLE	19.028	Up-regulation
STE_STE20_PAKA_PAK1_ST	P52565	ARHGDIA	Q13153	PAK1	S101	L94P	94	Missense	distal	-7	no	23.937	24.383	EPSD;PhosphoSitePlus	CCLE	19.028	Up-regulation
STE_STE20_PAKA_PAK1_ST	P52565	ARHGDIA	Q13153	PAK1	S174	Y175C	175	Missense	proximal	1	no	22.183	22.231	PhosphoSitePlus;EPSD	CCLE	19.028	Up-regulation
STE_STE20_PAKA_PAK1_ST	Q15365	PCBP1	Q13153	PAK1	T60	N66S	66	Missense	distal	6	no	20.436	20.251	PhosphoSitePlus;EPSD	CCLE	19.028	Down-regulation
STE_STE20_PAKA_PAK1_ST	P15056	BRAF	Q13153	PAK1	S429	R435S	435	Missense	distal	6	no	21.489	21.754	EPSD	CCLE	19.028	Up-regulation
STE_STE20_PAKA_PAK1_ST	P15056	BRAF	Q13153	PAK1	T440	R435S	435	Missense	distal	-5	no	19.506	19.535	EPSD	CCLE	19.028	Up-regulation
STE_STE20_PAKA_PAK1_ST	P15056	BRAF	Q13153	PAK1	S446	E451K	451	Missense	distal	5	no	31.164	31.171	PhosphoSitePlus	CCLE	19.028	Up-regulation
STE_STE20_PAKA_PAK1_ST	P15056	BRAF	Q13153	PAK1	S447	E451K	451	Missense	distal	4	no	23.244	23.391	EPSD	CCLE	19.028	Up-regulation
STE_STE20_PAKA_PAK1_ST	Q96T58	SPEN	Q13153	PAK1	S260	R264K	264	Missense	distal	4	no	18.129	19.131	EPSD	CCLE	19.028	Gain
STE_STE20_PAKA_PAK1_ST	Q96T58	SPEN	Q13153	PAK1	S270	R264K	264	Missense	distal	-6	no	22.190	20.132	EPSD	CCLE	19.028	Down-regulation
STE_STE20_PAKA_PAK1_ST	Q96T58	SPEN	Q13153	PAK1	S830	H829Y	829	Missense	proximal	-1	no	18.433	19.279	EPSD	CCLE	19.028	Gain
STE_STE20_PAKA_PAK1_ST	Q96T58	SPEN	Q13153	PAK1	S1082	S1076F	1076	Missense	distal	-6	no	20.210	19.444	EPSD	CCLE	19.028	Down-regulation
STE_STE20_PAKA_PAK1_ST	Q96T58	SPEN	Q13153	PAK1	S1222	Q1216E	1216	Missense	distal	-6	no	18.988	19.347	EPSD	CCLE	19.028	Gain
STE_STE20_PAKA_PAK1_ST	Q96T58	SPEN	Q13153	PAK1	S1252	Q1250R	1250	Missense	proximal	-2	no	14.857	24.064	EPSD	CCLE	19.028	Gain
STE_STE20_PAKA_PAK1_ST	Q96T58	SPEN	Q13153	PAK1	S1504	K1498R	1498	Missense	distal	-6	no	24.271	26.329	EPSD	CCLE	19.028	Up-regulation
STE_STE20_PAKA_PAK1_ST	Q96T58	SPEN	Q13153	PAK1	S2354	E2353Q	2353	Missense	proximal	-1	no	18.245	19.541	EPSD	CCLE	19.028	Gain
STE_STE20_PAKA_PAK1_ST	Q96T58	SPEN	Q13153	PAK1	S2392	T2399A	2399	Missense	distal	7	no	28.081	28.375	EPSD	CCLE	19.028	Up-regulation
STE_STE20_PAKA_PAK1_ST	Q96T58	SPEN	Q13153	PAK1	S2397	T2399A	2399	Missense	proximal	2	no	19.084	20.727	EPSD	CCLE	19.028	Up-regulation
STE_STE20_PAKA_PAK1_ST	Q96T58	SPEN	Q13153	PAK1	S3138	Q3135L	3135	Missense	distal	-3	no	17.704	19.937	EPSD	CCLE	19.028	Gain
STE_STE20_PAKA_PAK1_ST	Q96T58	SPEN	Q13153	PAK1	T3139	Q3135L	3135	Missense	distal	-4	no	20.528	20.683	EPSD	CCLE	19.028	Up-regulation
STE_STE20_PAKA_PAK1_ST	Q13761	RUNX3	Q13153	PAK1	S71	T69P	69	Missense	proximal	-2	no	22.360	23.698	EPSD	CCLE	19.028	Up-regulation
STE_STE20_PAKA_PAK1_ST	Q13761	RUNX3	Q13153	PAK1	T209	L204P	204	Missense	distal	-5	no	22.291	22.392	PhosphoSitePlus	CCLE	19.028	Up-regulation
STE_STE20_PAKA_PAK1_ST	Q70Z35	PREX2	Q13153	PAK1	S901	K904N	904	Missense	distal	3	no	19.357	20.745	EPSD	CCLE	19.028	Up-regulation
STE_STE20_PAKA_PAK1_ST	Q70Z35	PREX2	Q13153	PAK1	S907	K904N	904	Missense	distal	-3	no	23.618	15.773	EPSD	CCLE	19.028	Loss
STE_STE20_PAKA_PAK1_ST	Q13363	CTBP1	Q13153	PAK1	S298	E295K	295	Missense	distal	-3	no	9.142	22.934	EPSD	CCLE	19.028	Gain
STE_STE20_PAKA_PAK1_ST	Q8IYU2	HACE1	Q13153	PAK1	S385	E387G	387	Missense	proximal	2	no	27.095	28.216	PhosphoSitePlus	CCLE	19.028	Up-regulation
STE_STE20_PAKA_PAK1_ST	Q8IYU2	HACE1	Q13153	PAK1	T386	E387G	387	Missense	proximal	1	no	19.413	19.159	EPSD	CCLE	19.028	Down-regulation
STE_STE20_PAKA_PAK1_ST	P03372	ESR1	Q13153	PAK1	S236	A239D	239	Missense	distal	3	no	25.537	25.268	EPSD	CCLE	19.028	Down-regulation
STE_STE20_PAKA_PAK1_ST	Q15746	MYLK	Q13153	PAK1	S1208	K1207N	1207	Missense	proximal	-1	no	28.909	25.556	EPSD	CCLE	19.028	Down-regulation
STE_STE20_PAKA_PAK1_ST	Q15746	MYLK	Q13153	PAK1	S1209	K1207N	1207	Missense	proximal	-2	no	20.433	18.876	EPSD	CCLE	19.028	Loss
STE_STE20_PAKA_PAK1_ST	P08670	VIM	Q13153	PAK1	T35	Y38H	38	Missense	distal	3	no	19.576	16.210	EPSD	CCLE	19.028	Loss
STE_STE20_PAKA_PAK1_ST	P08670	VIM	Q13153	PAK1	S39	Y38H	38	Missense	proximal	-1	no	23.474	22.627	EPSD	CCLE	19.028	Down-regulation
STE_STE20_PAKA_PAK1_ST	P08670	VIM	Q13153	PAK1	S72	G76E	76	Missense	distal	4	no	22.107	21.150	EPSD	CCLE	19.028	Down-regulation
STE_STE20_PAKA_PAK1_ST	P08670	VIM	Q13153	PAK1	S73	G76E	76	Missense	distal	3	no	30.109	27.596	EPSD	CCLE	19.028	Down-regulation
STE_STE20_PAKA_PAK1_ST	P08670	VIM	Q13153	PAK1	S412	N417T	417	Missense	distal	5	no	22.616	22.596	EPSD	CCLE	19.028	Down-regulation
Atypical_Alpha_ChaK_TRPM6_ST	Q9BX84	TRPM6	Q9BX84	TRPM6	S1560	S1562A	1562	Missense	proximal	2	no	1.569	1.642	EPSD	CCLE	1.085	Up-regulation
Other_WNK_WNK1_ST	O94913	PCF11	Q9H4A3	WNK1	S502	R501L	501	Missense	proximal	-1	no	0.001	0.000	EPSD	CCLE	0.000	Down-regulation
Other_WNK_WNK1_ST	O94913	PCF11	Q9H4A3	WNK1	S502	S502P	502	Missense	central	0	yes	0.001	0.000	EPSD	CCLE	0.000	Loss
Other_WNK_WNK1_ST	Q9H4A3	WNK1	Q9H4A3	WNK1	S1220	S1220Y	1220	Missense	central	0	yes	0.000	0.000	EPSD	CCLE	0.000	Loss
Other_WNK_WNK1_ST	Q9H4A3	WNK1	Q9H4A3	WNK1	T1281	T1281A	1281	Missense	central	0	yes	0.000	0.000	EPSD	CCLE	0.000	Loss
Other_WNK_WNK1_ST	Q9H4A3	WNK1	Q9H4A3	WNK1	T1286	T1286I	1286	Missense	central	0	yes	0.000	0.000	EPSD	CCLE	0.000	Loss
Other_WNK_WNK1_ST	Q9UHW9	SLC12A6	Q9H4A3	WNK1	T945	T945A	945	Missense	central	0	yes	0.000	0.000	EPSD	CCLE	0.000	Loss
Other_WNK_WNK1_ST	Q9UHW9	SLC12A6	Q9H4A3	WNK1	T1040	E1039K	1039	Missense	proximal	-1	no	0.000	0.001	EPSD	CCLE	0.000	Up-regulation
Other_WNK_WNK1_ST	Q9UEW8	STK39	Q9H4A3	WNK1	S7	S7W	7	Missense	central	0	yes	0.000	0.000	EPSD	CCLE	0.000	Loss
Other_WNK_WNK1_ST	Q9UEW8	STK39	Q9H4A3	WNK1	S309	K312I	312	Missense	distal	3	no	0.000	0.001	EPSD	CCLE	0.000	Up-regulation
TK_InsR_INSR_Y	P35568	IRS1	P06213	INSR	Y750	S747A	747	Missense	distal	-3	no	10.498	7.231	EPSD	CCLE	10.312	Loss
TK_InsR_INSR_Y	P35568	IRS1	P06213	INSR	Y896	G902L	902	Missense	distal	6	no	13.644	13.454	EPSD;PhosphoSitePlus	CCLE	10.312	Down-regulation
TK_InsR_INSR_Y	P35568	IRS1	P06213	INSR	Y941	K943N	943	Missense	proximal	2	no	20.361	20.457	EPSD	CCLE	10.312	Up-regulation
TK_InsR_INSR_Y	P53004	BLVRA	P06213	INSR	Y198	E191G	191	Missense	distal	-7	no	12.819	12.293	EPSD;PhosphoSitePlus	CCLE	10.312	Down-regulation
TK_InsR_INSR_Y	P06213	INSR	P06213	INSR	Y1011	P1013L	1013	Missense	proximal	2	no	10.498	9.329	EPSD;PhosphoSitePlus	CCLE	10.312	Loss
TK_InsR_INSR_Y	P06213	INSR	P06213	INSR	Y1011	C1008S	1008	Missense	distal	-3	no	10.498	13.548	EPSD;PhosphoSitePlus	CCLE	10.312	Up-regulation
TK_InsR_INSR_Y	Q13480	GAB1	P06213	INSR	Y406	S402Y	402	Missense	distal	-4	no	10.487	8.335	EPSD	CCLE	10.312	Loss
TK_InsR_INSR_Y	Q13480	GAB1	P06213	INSR	Y447	M450T	450	Missense	distal	3	no	17.503	17.529	EPSD;PhosphoSitePlus	CCLE	10.312	Up-regulation
TK_InsR_INSR_Y	Q13480	GAB1	P06213	INSR	Y627	D629E	629	Missense	proximal	2	no	13.168	12.824	EPSD;PhosphoSitePlus	CCLE	10.312	Down-regulation
TK_InsR_INSR_Y	Q99704	DOK1	P06213	INSR	Y146	L145M	145	Missense	proximal	-1	no	10.363	12.056	EPSD	CCLE	10.312	Up-regulation
TK_InsR_INSR_Y	P60484	PTEN	P06213	INSR	Y27	L25Q	25	Missense	proximal	-2	no	9.201	13.531	EPSD;PhosphoSitePlus	CCLE	10.312	Gain
TK_InsR_INSR_Y	P29350	PTPN6	P06213	INSR	Y536	P542L	542	Missense	distal	6	no	17.447	17.374	PhosphoSitePlus	CCLE	10.312	Down-regulation
TK_InsR_INSR_Y	P29350	PTPN6	P06213	INSR	Y564	H568Y	568	Missense	distal	4	no	12.156	12.327	EPSD	CCLE	10.312	Up-regulation
STE_STE-Unique_MAP3K8_ST	Q14653	IRF3	P41279	MAP3K8	T244	P242S	242	Missense	proximal	-2	no	12.723	13.262	EPSD	CCLE	13.250	Gain
STE_STE-Unique_MAP3K8_ST	P15311	EZR	P41279	MAP3K8	T533	R529Q	529	Missense	distal	-4	no	20.836	21.000	EPSD	CCLE	13.250	Up-regulation
STE_STE-Unique_MAP3K8_ST	P15311	EZR	P41279	MAP3K8	T533	R526H	526	Missense	distal	-7	no	20.836	20.302	EPSD	CCLE	13.250	Down-regulation
STE_STE-Unique_MAP3K8_ST	P15311	EZR	P41279	MAP3K8	S536	R529Q	529	Missense	distal	-7	no	16.296	15.966	EPSD	CCLE	13.250	Down-regulation
STE_STE-Unique_MAP3K8_ST	P00519	ABL1	P41279	MAP3K8	T117	P112S	112	Missense	distal	-5	no	13.586	13.700	EPSD	CCLE	13.250	Up-regulation
STE_STE-Unique_MAP3K8_ST	P00519	ABL1	P41279	MAP3K8	T178	A179V	179	Missense	proximal	1	no	24.923	27.825	EPSD	CCLE	13.250	Up-regulation
STE_STE-Unique_MAP3K8_ST	P00519	ABL1	P41279	MAP3K8	T649	A647D	647	Missense	proximal	-2	no	18.109	18.558	EPSD	CCLE	13.250	Up-regulation
STE_STE-Unique_MAP3K8_ST	P00519	ABL1	P41279	MAP3K8	T653	A647D	647	Missense	distal	-6	no	15.652	16.179	EPSD	CCLE	13.250	Up-regulation
STE_STE-Unique_MAP3K8_ST	P00519	ABL1	P41279	MAP3K8	T751	G753V	753	Missense	proximal	2	no	15.410	15.553	EPSD	CCLE	13.250	Up-regulation
STE_STE-Unique_MAP3K8_ST	P00519	ABL1	P41279	MAP3K8	T751	H755Q	755	Missense	distal	4	no	15.410	15.242	EPSD	CCLE	13.250	Down-regulation
STE_STE-Unique_MAP3K8_ST	P00519	ABL1	P41279	MAP3K8	T823	L818I	818	Missense	distal	-5	no	22.219	22.246	EPSD	CCLE	13.250	Up-regulation
STE_STE-Unique_MAP3K8_ST	P00519	ABL1	P41279	MAP3K8	T823	A825V	825	Missense	proximal	2	no	22.219	22.523	EPSD	CCLE	13.250	Up-regulation
STE_STE-Unique_MAP3K8_ST	P00519	ABL1	P41279	MAP3K8	T823	P826S	826	Missense	distal	3	no	22.219	25.021	EPSD	CCLE	13.250	Up-regulation
STE_STE-Unique_MAP3K8_ST	P00519	ABL1	P41279	MAP3K8	T823	A827S	827	Missense	distal	4	no	22.219	24.903	EPSD	CCLE	13.250	Up-regulation
STE_STE-Unique_MAP3K8_ST	P00519	ABL1	P41279	MAP3K8	S828	A825V	825	Missense	distal	-3	no	9.744	15.009	EPSD	CCLE	13.250	Gain
STE_STE-Unique_MAP3K8_ST	P00519	ABL1	P41279	MAP3K8	S1115	Q1112L	1112	Missense	distal	-3	no	12.765	14.412	EPSD	CCLE	13.250	Gain
STE_STE-Unique_MAP3K8_ST	P52564	MAP2K6	P41279	MAP3K8	S207	D213H	213	Missense	distal	6	no	36.275	34.652	PhosphoSitePlus	CCLE	13.250	Down-regulation
STE_STE-Unique_MAP3K8_ST	Q13541	EIF4EBP1	P41279	MAP3K8	T70	P66H	66	Missense	distal	-4	no	22.215	22.038	PhosphoSitePlus	CCLE	13.250	Down-regulation
STE_STE-Unique_MAP3K8_ST	Q15418	RPS6KA1	P41279	MAP3K8	T348	A343P	343	Missense	distal	-5	no	13.207	13.250	EPSD	CCLE	13.250	Gain
STE_STE-Unique_MAP3K8_ST	O14757	CHEK1	P41279	MAP3K8	S286	T279A	279	Missense	distal	-7	no	16.636	16.540	EPSD	CCLE	13.250	Down-regulation
STE_STE-Unique_MAP3K8_ST	O14757	CHEK1	P41279	MAP3K8	S345	D351A	351	Missense	distal	6	no	22.388	20.688	PhosphoSitePlus	CCLE	13.250	Down-regulation
CMGC_MAPK_JNK_MAPK9_ST	O43602	DCX	P45984	MAPK9	T203	S206F	206	Missense	distal	3	no	142.330	141.978	EPSD	CCLE	140.458	Down-regulation
CMGC_MAPK_JNK_MAPK9_ST	O43602	DCX	P45984	MAPK9	S287	A286V	286	Missense	proximal	-1	no	155.605	155.376	EPSD	CCLE	140.458	Down-regulation
CMGC_MAPK_JNK_MAPK9_ST	O43602	DCX	P45984	MAPK9	T289	A286V	286	Missense	distal	-3	no	157.792	156.327	EPSD	CCLE	140.458	Down-regulation
CMGC_MAPK_JNK_MAPK9_ST	O43602	DCX	P45984	MAPK9	S306	P307Q	307	Missense	proximal	1	no	156.799	136.687	EPSD	CCLE	140.458	Loss
CMGC_MAPK_JNK_MAPK9_ST	P10636	MAPT	P45984	MAPK9	S64	A66V	66	Missense	proximal	2	no	144.805	144.946	EPSD	CCLE	140.458	Up-regulation
CMGC_MAPK_JNK_MAPK9_ST	P10636	MAPT	P45984	MAPK9	S68	A66V	66	Missense	proximal	-2	no	141.235	138.231	EPSD	CCLE	140.458	Loss
CMGC_MAPK_JNK_MAPK9_ST	P10636	MAPT	P45984	MAPK9	T69	A66V	66	Missense	distal	-3	no	157.136	155.671	EPSD	CCLE	140.458	Down-regulation
CMGC_MAPK_JNK_MAPK9_ST	P10636	MAPT	P45984	MAPK9	T102	G107V	107	Missense	distal	5	no	140.567	140.419	EPSD	CCLE	140.458	Loss
CMGC_MAPK_JNK_MAPK9_ST	P10636	MAPT	P45984	MAPK9	T111	G107V	107	Missense	distal	-4	no	150.649	151.081	EPSD	CCLE	140.458	Up-regulation
CMGC_MAPK_JNK_MAPK9_ST	P10636	MAPT	P45984	MAPK9	T173	G174A	174	Missense	proximal	1	no	-10.078	147.168	EPSD	CCLE	140.458	Gain
CMGC_MAPK_JNK_MAPK9_ST	P10636	MAPT	P45984	MAPK9	S228	D221Y	221	Missense	distal	-7	no	156.450	153.770	EPSD	CCLE	140.458	Down-regulation
CMGC_MAPK_JNK_MAPK9_ST	P10636	MAPT	P45984	MAPK9	S228	P234S	234	Missense	distal	6	no	156.450	156.476	EPSD	CCLE	140.458	Up-regulation
CMGC_MAPK_JNK_MAPK9_ST	P10636	MAPT	P45984	MAPK9	S232	P234S	234	Missense	proximal	2	no	154.055	154.151	EPSD	CCLE	140.458	Up-regulation
CMGC_MAPK_JNK_MAPK9_ST	P10636	MAPT	P45984	MAPK9	S238	P234S	234	Missense	distal	-4	no	155.330	155.509	EPSD	CCLE	140.458	Up-regulation
CMGC_MAPK_JNK_MAPK9_ST	P10636	MAPT	P45984	MAPK9	S238	D242H	242	Missense	distal	4	no	155.330	155.213	EPSD	CCLE	140.458	Down-regulation
CMGC_MAPK_JNK_MAPK9_ST	P10636	MAPT	P45984	MAPK9	T248	D242H	242	Missense	distal	-6	no	146.145	146.314	EPSD	CCLE	140.458	Up-regulation
CMGC_MAPK_JNK_MAPK9_ST	P10636	MAPT	P45984	MAPK9	T248	S255N	255	Missense	distal	7	no	146.145	145.969	EPSD	CCLE	140.458	Down-regulation
CMGC_MAPK_JNK_MAPK9_ST	P10636	MAPT	P45984	MAPK9	S411	K405R	405	Missense	distal	-6	no	157.243	157.431	EPSD	CCLE	140.458	Up-regulation
CMGC_MAPK_JNK_MAPK9_ST	P10636	MAPT	P45984	MAPK9	S438	V442I	442	Missense	distal	4	no	167.104	167.145	EPSD	CCLE	140.458	Up-regulation
CMGC_MAPK_JNK_MAPK9_ST	P10636	MAPT	P45984	MAPK9	S516	R511H	511	Missense	distal	-5	no	152.372	152.428	EPSD	CCLE	140.458	Up-regulation
CMGC_MAPK_JNK_MAPK9_ST	P10636	MAPT	P45984	MAPK9	S516	G518S	518	Missense	proximal	2	no	152.372	152.316	EPSD	CCLE	140.458	Down-regulation
CMGC_MAPK_JNK_MAPK9_ST	P10636	MAPT	P45984	MAPK9	S519	G518S	518	Missense	proximal	-1	no	159.830	159.892	EPSD	CCLE	140.458	Up-regulation
CMGC_MAPK_JNK_MAPK9_ST	P10636	MAPT	P45984	MAPK9	S519	R526L	526	Missense	distal	7	no	159.830	160.663	EPSD	CCLE	140.458	Up-regulation
CMGC_MAPK_JNK_MAPK9_ST	P10636	MAPT	P45984	MAPK9	T522	G518S	518	Missense	distal	-4	no	159.360	160.894	EPSD	CCLE	140.458	Up-regulation
CMGC_MAPK_JNK_MAPK9_ST	P10636	MAPT	P45984	MAPK9	T522	R526L	526	Missense	distal	4	no	159.360	159.747	EPSD	CCLE	140.458	Up-regulation
CMGC_MAPK_JNK_MAPK9_ST	P10636	MAPT	P45984	MAPK9	T529	R526L	526	Missense	distal	-3	no	158.082	156.830	EPSD	CCLE	140.458	Down-regulation
CMGC_MAPK_JNK_MAPK9_ST	P10636	MAPT	P45984	MAPK9	S552	R559H	559	Missense	distal	7	no	154.476	155.073	EPSD	CCLE	140.458	Up-regulation
CMGC_MAPK_JNK_MAPK9_ST	P10636	MAPT	P45984	MAPK9	S555	R559H	559	Missense	distal	4	no	142.317	142.598	EPSD	CCLE	140.458	Up-regulation
CMGC_MAPK_JNK_MAPK9_ST	P10636	MAPT	P45984	MAPK9	T562	R559H	559	Missense	distal	-3	no	144.903	142.517	EPSD	CCLE	140.458	Down-regulation
CMGC_MAPK_JNK_MAPK9_ST	P10636	MAPT	P45984	MAPK9	S579	K574N	574	Missense	distal	-5	no	141.032	140.986	EPSD	CCLE	140.458	Down-regulation
CMGC_MAPK_JNK_MAPK9_ST	P10636	MAPT	P45984	MAPK9	T703	G706V	706	Missense	distal	3	no	143.500	143.584	EPSD	CCLE	140.458	Up-regulation
CMGC_MAPK_JNK_MAPK9_ST	P10636	MAPT	P45984	MAPK9	S713	G706V	706	Missense	distal	-7	no	148.590	147.996	EPSD	CCLE	140.458	Down-regulation
CMGC_MAPK_JNK_MAPK9_ST	P10636	MAPT	P45984	MAPK9	S713	S717C	717	Missense	distal	4	no	148.590	148.734	EPSD	CCLE	140.458	Up-regulation
CMGC_MAPK_JNK_MAPK9_ST	P10636	MAPT	P45984	MAPK9	S721	S717C	717	Missense	distal	-4	no	151.648	150.378	EPSD	CCLE	140.458	Down-regulation
CMGC_MAPK_JNK_MAPK9_ST	P10636	MAPT	P45984	MAPK9	S721	S721C	721	Missense	central	0	yes	151.648	0.000	EPSD	CCLE	140.458	Loss
CMGC_MAPK_JNK_MAPK9_ST	P10636	MAPT	P45984	MAPK9	S721	H724R	724	Missense	distal	3	no	151.648	151.919	EPSD	CCLE	140.458	Up-regulation
CMGC_MAPK_JNK_MAPK9_ST	P10636	MAPT	P45984	MAPK9	S739	Q741K	741	Missense	proximal	2	no	150.893	150.924	EPSD	CCLE	140.458	Up-regulation
CMGC_MAPK_JNK_MAPK9_ST	P15336	ATF2	P45984	MAPK9	T69	R74K	74	Missense	distal	5	no	157.619	158.019	PhosphoSitePlus;EPSD	CCLE	140.458	Up-regulation
CMGC_MAPK_JNK_MAPK9_ST	P15336	ATF2	P45984	MAPK9	T71	R74K	74	Missense	distal	3	no	157.277	157.111	EPSD;PhosphoSitePlus	CCLE	140.458	Down-regulation
CMGC_MAPK_JNK_MAPK9_ST	P15336	ATF2	P45984	MAPK9	T325	A330G	330	Missense	distal	5	no	157.279	157.844	EPSD	CCLE	140.458	Up-regulation
CMGC_MAPK_JNK_MAPK9_ST	P15336	ATF2	P45984	MAPK9	T325	A319D	319	Missense	distal	-6	no	157.279	156.785	EPSD	CCLE	140.458	Down-regulation
CMGC_MAPK_JNK_MAPK9_ST	P15336	ATF2	P45984	MAPK9	S328	A330G	330	Missense	proximal	2	no	160.859	161.000	EPSD	CCLE	140.458	Up-regulation
CMGC_MAPK_JNK_MAPK9_ST	P15336	ATF2	P45984	MAPK9	T333	A330G	330	Missense	distal	-3	no	152.446	150.767	EPSD	CCLE	140.458	Down-regulation
CMGC_MAPK_JNK_MAPK9_ST	P01106	MYC	P45984	MAPK9	T58	E54K	54	Missense	distal	-4	no	162.904	161.786	EPSD	CCLE	140.458	Down-regulation
CMGC_MAPK_JNK_MAPK9_ST	P01106	MYC	P45984	MAPK9	T58	P57H	57	Missense	proximal	-1	no	162.904	162.660	EPSD	CCLE	140.458	Down-regulation
CMGC_MAPK_JNK_MAPK9_ST	P01106	MYC	P45984	MAPK9	S62	P57H	57	Missense	distal	-5	no	156.539	156.588	EPSD;PhosphoSitePlus	CCLE	140.458	Up-regulation
CMGC_MAPK_JNK_MAPK9_ST	P01106	MYC	P45984	MAPK9	S62	L69I	69	Missense	distal	7	no	156.539	156.358	EPSD;PhosphoSitePlus	CCLE	140.458	Down-regulation
CMGC_MAPK_JNK_MAPK9_ST	P01106	MYC	P45984	MAPK9	S71	L69I	69	Missense	proximal	-2	no	158.457	156.394	PhosphoSitePlus;EPSD	CCLE	140.458	Down-regulation
CMGC_MAPK_JNK_MAPK9_ST	P01106	MYC	P45984	MAPK9	S71	Y74S	74	Missense	distal	3	no	158.457	158.856	PhosphoSitePlus;EPSD	CCLE	140.458	Up-regulation
CMGC_MAPK_JNK_MAPK9_ST	P01106	MYC	P45984	MAPK9	S71	T78R	78	Missense	distal	7	no	158.457	157.740	PhosphoSitePlus;EPSD	CCLE	140.458	Down-regulation
CMGC_MAPK_JNK_MAPK9_ST	P01106	MYC	P45984	MAPK9	T78	Y74S	74	Missense	distal	-4	no	156.598	159.606	EPSD	CCLE	140.458	Up-regulation
CMGC_MAPK_JNK_MAPK9_ST	P01106	MYC	P45984	MAPK9	T78	T78R	78	Missense	central	0	yes	156.598	0.000	EPSD	CCLE	140.458	Loss
CMGC_MAPK_JNK_MAPK9_ST	P01106	MYC	P45984	MAPK9	T78	L82F	82	Missense	distal	4	no	156.598	156.829	EPSD	CCLE	140.458	Up-regulation
CMGC_MAPK_JNK_MAPK9_ST	P01106	MYC	P45984	MAPK9	S204	K206T	206	Missense	proximal	2	no	148.093	148.219	EPSD	CCLE	140.458	Up-regulation
CMGC_MAPK_JNK_MAPK9_ST	P05067	APP	P45984	MAPK9	T381	E385K	385	Missense	distal	4	no	152.510	152.608	EPSD	CCLE	140.458	Up-regulation
CMGC_MAPK_JNK_MAPK9_ST	P05067	APP	P45984	MAPK9	T743	D739V	739	Missense	distal	-4	no	158.371	157.973	EPSD	CCLE	140.458	Down-regulation
CMGC_MAPK_JNK_MAPK9_ST	P19793	RXRA	P45984	MAPK9	S21	R25Q	25	Missense	distal	4	no	156.099	156.109	EPSD	CCLE	140.458	Up-regulation
CMGC_MAPK_JNK_MAPK9_ST	P19793	RXRA	P45984	MAPK9	S49	S52I	52	Missense	distal	3	no	158.363	158.248	EPSD	CCLE	140.458	Down-regulation
CMGC_MAPK_JNK_MAPK9_ST	P19793	RXRA	P45984	MAPK9	T82	M77I	77	Missense	distal	-5	no	155.980	156.089	EPSD	CCLE	140.458	Up-regulation
CMGC_MAPK_JNK_MAPK9_ST	P19793	RXRA	P45984	MAPK9	S222	N227S	227	Missense	distal	5	no	142.947	143.177	EPSD	CCLE	140.458	Up-regulation
CMGC_MAPK_JNK_MAPK9_ST	P19793	RXRA	P45984	MAPK9	S225	N227S	227	Missense	proximal	2	no	141.453	141.542	EPSD	CCLE	140.458	Up-regulation
CMGC_MAPK_JNK_MAPK9_ST	Q8WYK2	JDP2	P45984	MAPK9	T143	R142Q	142	Missense	proximal	-1	no	141.208	141.159	EPSD	CCLE	140.458	Down-regulation
CMGC_MAPK_JNK_MAPK9_ST	Q8WYK2	JDP2	P45984	MAPK9	T148	R142Q	142	Missense	distal	-6	no	154.686	154.614	PhosphoSitePlus	CCLE	140.458	Down-regulation
CMGC_MAPK_JNK_MAPK9_ST	P50616	TOB1	P45984	MAPK9	S205	V201F	201	Missense	distal	-4	no	155.937	153.756	EPSD	CCLE	140.458	Down-regulation
CMGC_MAPK_JNK_MAPK9_ST	Q07817	BCL2L1	P45984	MAPK9	T47	E42D	42	Missense	distal	-5	no	161.645	161.749	PhosphoSitePlus;EPSD	CCLE	140.458	Up-regulation
CMGC_MAPK_JNK_MAPK9_ST	Q07817	BCL2L1	P45984	MAPK9	S62	S62N	62	Missense	central	0	yes	156.992	0.000	EPSD;PhosphoSitePlus	CCLE	140.458	Loss
CMGC_MAPK_JNK_MAPK9_ST	Q14934	NFATC4	P45984	MAPK9	S168	S174N	174	Missense	distal	6	no	152.516	152.819	EPSD	CCLE	140.458	Up-regulation
CMGC_MAPK_JNK_MAPK9_ST	Q14934	NFATC4	P45984	MAPK9	S170	S174N	174	Missense	distal	4	no	149.415	149.381	EPSD	CCLE	140.458	Down-regulation
CMGC_MAPK_JNK_MAPK9_ST	Q14934	NFATC4	P45984	MAPK9	S217	S221F	221	Missense	distal	4	no	169.743	170.248	PhosphoSitePlus;EPSD	CCLE	140.458	Up-regulation
CMGC_MAPK_JNK_MAPK9_ST	Q14934	NFATC4	P45984	MAPK9	S221	S221F	221	Missense	central	0	yes	153.960	0.000	EPSD	CCLE	140.458	Loss
CMGC_MAPK_JNK_MAPK9_ST	Q14934	NFATC4	P45984	MAPK9	T226	S221F	221	Missense	distal	-5	no	161.694	161.837	EPSD	CCLE	140.458	Up-regulation
CMGC_MAPK_JNK_MAPK9_ST	Q14934	NFATC4	P45984	MAPK9	S592	A590T	590	Missense	proximal	-2	no	161.627	159.261	EPSD	CCLE	140.458	Down-regulation
CMGC_MAPK_JNK_MAPK9_ST	Q14934	NFATC4	P45984	MAPK9	S716	P720L	720	Missense	distal	4	no	152.457	152.833	EPSD	CCLE	140.458	Up-regulation
CMGC_MAPK_JNK_MAPK9_ST	Q14934	NFATC4	P45984	MAPK9	S819	P820L	820	Missense	proximal	1	no	163.760	118.857	EPSD	CCLE	140.458	Loss
CMGC_MAPK_JNK_MAPK9_ST	Q9UGP4	LIMD1	P45984	MAPK9	S187	N182S	182	Missense	distal	-5	no	148.491	148.516	EPSD	CCLE	140.458	Up-regulation
CMGC_MAPK_JNK_MAPK9_ST	Q9UGP4	LIMD1	P45984	MAPK9	S298	S304T	304	Missense	distal	6	no	142.141	141.865	EPSD	CCLE	140.458	Down-regulation
CMGC_MAPK_JNK_MAPK9_ST	Q9UGP4	LIMD1	P45984	MAPK9	S421	S421N	421	Missense	central	0	yes	148.618	0.000	EPSD;PhosphoSitePlus	CCLE	140.458	Loss
CMGC_MAPK_JNK_MAPK9_ST	Q9UGP4	LIMD1	P45984	MAPK9	S424	S421N	421	Missense	distal	-3	no	154.717	155.371	EPSD;PhosphoSitePlus	CCLE	140.458	Up-regulation
CMGC_MAPK_JNK_MAPK9_ST	Q12968	NFATC3	P45984	MAPK9	S207	S211Y	211	Missense	distal	4	no	152.556	153.062	EPSD	CCLE	140.458	Up-regulation
CMGC_MAPK_JNK_MAPK9_ST	Q12968	NFATC3	P45984	MAPK9	S211	S211Y	211	Missense	central	0	yes	157.802	0.000	EPSD	CCLE	140.458	Loss
CMGC_MAPK_JNK_MAPK9_ST	Q12968	NFATC3	P45984	MAPK9	S215	S211Y	211	Missense	distal	-4	no	152.834	149.826	EPSD	CCLE	140.458	Down-regulation
CMGC_MAPK_JNK_MAPK9_ST	Q12968	NFATC3	P45984	MAPK9	S215	E222K	222	Missense	distal	7	no	152.834	153.085	EPSD	CCLE	140.458	Up-regulation
CMGC_MAPK_JNK_MAPK9_ST	Q12968	NFATC3	P45984	MAPK9	S269	S265L	265	Missense	distal	-4	no	162.521	160.330	EPSD	CCLE	140.458	Down-regulation
CMGC_MAPK_JNK_MAPK9_ST	P04637	TP53	P45984	MAPK9	S33	E28Q	28	Missense	distal	-5	no	154.719	154.725	EPSD	CCLE	140.458	Up-regulation
CMGC_MAPK_JNK_MAPK9_ST	Q9UIG0	BAZ1B	P45984	MAPK9	S46	Y45C	45	Missense	proximal	-1	no	142.052	142.331	EPSD	CCLE	140.458	Up-regulation
CMGC_MAPK_JNK_MAPK9_ST	Q9UIG0	BAZ1B	P45984	MAPK9	S330	K335Q	335	Missense	distal	5	no	156.612	156.421	EPSD	CCLE	140.458	Down-regulation
CMGC_MAPK_JNK_MAPK9_ST	Q9UIG0	BAZ1B	P45984	MAPK9	S361	K360T	360	Missense	proximal	-1	no	152.171	152.001	EPSD	CCLE	140.458	Down-regulation
CMGC_MAPK_JNK_MAPK9_ST	Q9UIG0	BAZ1B	P45984	MAPK9	S1259	S1259N	1259	Missense	central	0	yes	141.753	0.000	EPSD	CCLE	140.458	Loss
CMGC_MAPK_JNK_MAPK9_ST	P30307	CDC25C	P45984	MAPK9	S191	S198A	198	Missense	distal	7	no	140.501	140.196	EPSD	CCLE	140.458	Loss
CMGC_MAPK_JNK_MAPK9_ST	P55957	BID	P45984	MAPK9	T59	N62T	62	Missense	distal	3	no	149.467	149.224	PhosphoSitePlus	CCLE	140.458	Down-regulation
CMGC_MAPK_JNK_MAPK9_ST	Q8IW41	MAPKAPK5	P45984	MAPK9	S212	P213L	213	Missense	proximal	1	no	161.944	117.041	EPSD	CCLE	140.458	Loss
CMGC_MAPK_JNK_MAPK9_ST	Q8IW41	MAPKAPK5	P45984	MAPK9	T214	P213L	213	Missense	proximal	-1	no	156.012	155.856	EPSD	CCLE	140.458	Down-regulation
CMGC_MAPK_JNK_MAPK9_ST	P29966	MARCKS	P45984	MAPK9	S27	A25T	25	Missense	proximal	-2	no	160.346	157.980	EPSD	CCLE	140.458	Down-regulation
CMGC_MAPK_JNK_MAPK9_ST	P29966	MARCKS	P45984	MAPK9	S46	A50T	50	Missense	distal	4	no	159.243	159.414	PhosphoSitePlus	CCLE	140.458	Up-regulation
CMGC_MAPK_JNK_MAPK9_ST	P29966	MARCKS	P45984	MAPK9	S63	D68G	68	Missense	distal	5	no	143.236	143.248	EPSD	CCLE	140.458	Up-regulation
CMGC_MAPK_JNK_MAPK9_ST	P29966	MARCKS	P45984	MAPK9	S81	A79V	79	Missense	proximal	-2	no	160.004	156.999	EPSD	CCLE	140.458	Down-regulation
CMGC_MAPK_JNK_MAPK9_ST	P29966	MARCKS	P45984	MAPK9	S81	A84S	84	Missense	distal	3	no	160.004	159.907	EPSD	CCLE	140.458	Down-regulation
CMGC_MAPK_JNK_MAPK9_ST	P29966	MARCKS	P45984	MAPK9	S83	A79V	79	Missense	distal	-4	no	143.951	142.295	EPSD	CCLE	140.458	Down-regulation
CMGC_MAPK_JNK_MAPK9_ST	P29966	MARCKS	P45984	MAPK9	S83	A84S	84	Missense	proximal	1	no	143.951	-118.199	EPSD	CCLE	140.458	Loss
CMGC_MAPK_JNK_MAPK9_ST	P29966	MARCKS	P45984	MAPK9	S101	A95G	95	Missense	distal	-6	no	161.169	160.894	EPSD	CCLE	140.458	Down-regulation
CMGC_MAPK_JNK_MAPK9_ST	P29966	MARCKS	P45984	MAPK9	S101	E106K	106	Missense	distal	5	no	161.169	161.313	EPSD	CCLE	140.458	Up-regulation
CMGC_MAPK_JNK_MAPK9_ST	P29966	MARCKS	P45984	MAPK9	S118	E123K	123	Missense	distal	5	no	162.494	162.638	EPSD	CCLE	140.458	Up-regulation
CMGC_MAPK_JNK_MAPK9_ST	P29966	MARCKS	P45984	MAPK9	S118	E123A	123	Missense	distal	5	no	162.494	162.482	EPSD	CCLE	140.458	Down-regulation
CMGC_MAPK_JNK_MAPK9_ST	P29966	MARCKS	P45984	MAPK9	S118	G124R	124	Missense	distal	6	no	162.494	162.707	EPSD	CCLE	140.458	Up-regulation
CMGC_MAPK_JNK_MAPK9_ST	P29966	MARCKS	P45984	MAPK9	T120	E123K	123	Missense	distal	3	no	140.766	140.720	EPSD	CCLE	140.458	Down-regulation
CMGC_MAPK_JNK_MAPK9_ST	P29966	MARCKS	P45984	MAPK9	T120	E123A	123	Missense	distal	3	no	140.766	140.826	EPSD	CCLE	140.458	Up-regulation
CMGC_MAPK_JNK_MAPK9_ST	P29966	MARCKS	P45984	MAPK9	T120	G124R	124	Missense	distal	4	no	140.766	140.446	EPSD	CCLE	140.458	Loss
CMGC_MAPK_JNK_MAPK9_ST	P29966	MARCKS	P45984	MAPK9	S128	E123K	123	Missense	distal	-5	no	145.975	146.008	EPSD	CCLE	140.458	Up-regulation
CMGC_MAPK_JNK_MAPK9_ST	P29966	MARCKS	P45984	MAPK9	S128	E123A	123	Missense	distal	-5	no	145.975	145.994	EPSD	CCLE	140.458	Up-regulation
CMGC_MAPK_JNK_MAPK9_ST	P29966	MARCKS	P45984	MAPK9	S128	G124R	124	Missense	distal	-4	no	145.975	147.210	EPSD	CCLE	140.458	Up-regulation
CMGC_MAPK_JNK_MAPK9_ST	P29966	MARCKS	P45984	MAPK9	S132	P136L	136	Missense	distal	4	no	145.868	146.244	EPSD	CCLE	140.458	Up-regulation
CMGC_MAPK_JNK_MAPK9_ST	P29966	MARCKS	P45984	MAPK9	S135	P136L	136	Missense	proximal	1	no	160.014	115.111	EPSD	CCLE	140.458	Loss
CMGC_MAPK_JNK_MAPK9_ST	P29966	MARCKS	P45984	MAPK9	T143	P136L	136	Missense	distal	-7	no	160.528	159.400	EPSD	CCLE	140.458	Down-regulation
CMGC_MAPK_JNK_MAPK9_ST	P29966	MARCKS	P45984	MAPK9	T143	S145A	145	Missense	proximal	2	no	160.528	160.443	EPSD	CCLE	140.458	Down-regulation
CMGC_MAPK_JNK_MAPK9_ST	P29966	MARCKS	P45984	MAPK9	S145	S145A	145	Missense	central	0	yes	164.178	0.000	EPSD	CCLE	140.458	Loss
CMGC_MAPK_JNK_MAPK9_ST	P29966	MARCKS	P45984	MAPK9	T150	S145A	145	Missense	distal	-5	no	157.787	157.795	EPSD	CCLE	140.458	Up-regulation
CMGC_MAPK_JNK_MAPK9_ST	P11802	CDK4	P45984	MAPK9	T172	A170T	170	Missense	proximal	-2	no	155.631	153.264	PhosphoSitePlus	CCLE	140.458	Down-regulation
CMGC_MAPK_JNK_MAPK9_ST	Q9UQF2	MAPK8IP1	P45984	MAPK9	T103	D98G	98	Missense	distal	-5	no	156.598	156.572	PhosphoSitePlus	CCLE	140.458	Down-regulation
CMGC_MAPK_JNK_MAPK9_ST	Q9UQF2	MAPK8IP1	P45984	MAPK9	S341	D337N	337	Missense	distal	-4	no	160.263	162.284	EPSD	CCLE	140.458	Up-regulation
CMGC_MAPK_JNK_MAPK9_ST	Q9UQF2	MAPK8IP1	P45984	MAPK9	S341	S340L	340	Missense	proximal	-1	no	160.263	160.220	EPSD	CCLE	140.458	Down-regulation
CMGC_MAPK_JNK_MAPK9_ST	Q9NYV6	RRN3	P45984	MAPK9	S44	P45H	45	Missense	proximal	1	no	152.328	-7.778	EPSD	CCLE	140.458	Loss
CMGC_MAPK_JNK_MAPK9_ST	Q9NYV6	RRN3	P45984	MAPK9	T200	P206S	206	Missense	distal	6	no	157.330	157.356	PhosphoSitePlus	CCLE	140.458	Up-regulation
CMGC_MAPK_JNK_MAPK9_ST	Q9NYV6	RRN3	P45984	MAPK9	T200	P201L	201	Missense	proximal	1	no	157.330	112.427	PhosphoSitePlus	CCLE	140.458	Loss
CMGC_MAPK_JNK_MAPK9_ST	Q9NYV6	RRN3	P45984	MAPK9	T200	A194T	194	Missense	distal	-6	no	157.330	156.975	PhosphoSitePlus	CCLE	140.458	Down-regulation
AGC_NDR_LATS_LATS2_ST	Q9NQS7	INCENP	Q9NRM7	LATS2	S91	R88C	88	Missense	distal	-3	no	0.052	0.005	EPSD	CCLE	0.004	Down-regulation
AGC_NDR_LATS_LATS2_ST	Q9NQS7	INCENP	Q9NRM7	LATS2	S103	K109T	109	Missense	distal	6	no	0.056	0.055	EPSD	CCLE	0.004	Down-regulation
AGC_NDR_LATS_LATS2_ST	Q9NQS7	INCENP	Q9NRM7	LATS2	S336	K341R	341	Missense	distal	5	no	0.047	0.046	EPSD	CCLE	0.004	Down-regulation
AGC_NDR_LATS_LATS2_ST	P00519	ABL1	Q9NRM7	LATS2	T178	A179V	179	Missense	proximal	1	no	0.067	0.068	EPSD	CCLE	0.004	Up-regulation
AGC_NDR_LATS_LATS2_ST	P00519	ABL1	Q9NRM7	LATS2	T224	T224I	224	Missense	central	0	yes	0.004	0.000	EPSD	CCLE	0.004	Loss
AGC_NDR_LATS_LATS2_ST	P00519	ABL1	Q9NRM7	LATS2	S601	N598S	598	Missense	distal	-3	no	0.004	0.001	EPSD	CCLE	0.004	Loss
AGC_NDR_LATS_LATS2_ST	P00519	ABL1	Q9NRM7	LATS2	S642	R639Q	639	Missense	distal	-3	no	0.051	0.002	EPSD	CCLE	0.004	Loss
AGC_NDR_LATS_LATS2_ST	P00519	ABL1	Q9NRM7	LATS2	T700	T700I	700	Missense	central	0	yes	0.050	0.000	EPSD	CCLE	0.004	Loss
AGC_NDR_LATS_LATS2_ST	P00519	ABL1	Q9NRM7	LATS2	T823	L818I	818	Missense	distal	-5	no	0.049	0.048	EPSD	CCLE	0.004	Down-regulation
AGC_NDR_LATS_LATS2_ST	P46937	YAP1	Q9NRM7	LATS2	S419	D421N	421	Missense	proximal	2	no	0.005	0.004	EPSD	CCLE	0.004	Down-regulation
AGC_NDR_LATS_LATS2_ST	P61981	YWHAG	Q9NRM7	LATS2	S59	R56C	56	Missense	distal	-3	no	0.052	0.005	PhosphoSitePlus	CCLE	0.004	Down-regulation
AGC_NDR_LATS_LATS2_ST	P61981	YWHAG	Q9NRM7	LATS2	T139	A138D	138	Missense	proximal	-1	no	0.004	0.003	EPSD	CCLE	0.004	Loss
AGC_NDR_LATS_LATS2_ST	Q02241	KIF23	Q9NRM7	LATS2	S814	S814C	814	Missense	central	0	yes	0.066	0.000	PhosphoSitePlus;EPSD	CCLE	0.004	Loss
AGC_NDR_LATS_LATS2_ST	Q4VCS5	AMOT	Q9NRM7	LATS2	T750	I755S	755	Missense	distal	5	no	0.047	0.048	EPSD	CCLE	0.004	Up-regulation
AGC_NDR_LATS_LATS2_ST	Q9GZV5	WWTR1	Q9NRM7	LATS2	S66	G72C	72	Missense	distal	6	no	0.057	0.058	EPSD	CCLE	0.004	Up-regulation
AGC_NDR_LATS_LATS2_ST	Q9GZV5	WWTR1	Q9NRM7	LATS2	T67	G72C	72	Missense	distal	5	no	0.003	0.004	EPSD	CCLE	0.004	Gain
AGC_NDR_LATS_LATS2_ST	Q9GZV5	WWTR1	Q9NRM7	LATS2	S87	S87L	87	Missense	central	0	yes	0.005	0.000	EPSD	CCLE	0.004	Loss
Other_CAMKK_CAMKK-Meta_CAMKK2_ST	Q96EB6	SIRT1	Q96RR4	CAMKK2	S27	A29T	29	Missense	proximal	2	no	33.029	32.009	EPSD;PhosphoSitePlus	CCLE	15.642	Down-regulation
Other_CAMKK_CAMKK-Meta_CAMKK2_ST	Q96EB6	SIRT1	Q96RR4	CAMKK2	S659	E662D	662	Missense	distal	3	no	24.628	23.624	EPSD	CCLE	15.642	Down-regulation
Other_CAMKK_CAMKK-Meta_CAMKK2_ST	Q96RR4	CAMKK2	Q96RR4	CAMKK2	T350	P351S	351	Missense	proximal	1	no	18.401	18.511	EPSD	CCLE	15.642	Up-regulation
Other_CAMKK_CAMKK-Meta_CAMKK2_ST	Q13131	PRKAA1	Q96RR4	CAMKK2	T355	S356N	356	Missense	proximal	1	no	15.719	11.448	EPSD	CCLE	15.642	Loss
Other_CAMKK_CAMKK-Meta_CAMKK2_ST	Q13131	PRKAA1	Q96RR4	CAMKK2	T522	L521V	521	Missense	proximal	-1	no	16.398	16.593	EPSD	CCLE	15.642	Up-regulation
Other_CAMKK_CAMKK-Meta_CAMKK2_ST	Q13131	PRKAA1	Q96RR4	CAMKK2	S527	L521V	521	Missense	distal	-6	no	22.652	22.753	EPSD	CCLE	15.642	Up-regulation
Other_CAMKK_CAMKK-Meta_CAMKK2_ST	P54646	PRKAA2	Q96RR4	CAMKK2	T172	R171I	171	Missense	proximal	-1	no	44.267	44.185	PhosphoSitePlus	CCLE	15.642	Down-regulation
Other_CAMKK_CAMKK-Meta_CAMKK2_ST	P54646	PRKAA2	Q96RR4	CAMKK2	S173	R171I	171	Missense	proximal	-2	no	16.125	16.375	EPSD	CCLE	15.642	Up-regulation
Other_CAMKK_CAMKK-Meta_CAMKK2_ST	P31749	AKT1	Q96RR4	CAMKK2	S457	V461A	461	Missense	distal	4	no	15.842	18.597	EPSD	CCLE	15.642	Up-regulation
Other_CAMKK_CAMKK-Meta_CAMKK2_ST	P31749	AKT1	Q96RR4	CAMKK2	S457	M458T	458	Missense	proximal	1	no	15.842	15.997	EPSD	CCLE	15.642	Up-regulation
TK_FGFR_FGFR1_Y	Q9UBW7	ZMYM2	P11362	FGFR1	Y557	M558R	558	Missense	proximal	1	no	7.516	7.519	EPSD;PhosphoSitePlus	CCLE	5.471	Up-regulation
TK_FGFR_FGFR1_Y	Q9Y2J4	AMOTL2	P11362	FGFR1	Y107	E103G	103	Missense	distal	-4	no	7.154	6.975	PhosphoSitePlus	CCLE	5.471	Down-regulation
TK_FGFR_FGFR1_Y	Q15118	PDK1	P11362	FGFR1	Y243	Y243H	243	Missense	central	0	yes	8.210	0.000	EPSD;PhosphoSitePlus	CCLE	5.471	Loss
TK_FGFR_FGFR1_Y	Q15118	PDK1	P11362	FGFR1	Y243	N246H	246	Missense	distal	3	no	8.210	6.257	EPSD;PhosphoSitePlus	CCLE	5.471	Down-regulation
TK_FGFR_FGFR1_Y	Q15118	PDK1	P11362	FGFR1	Y244	Y243H	243	Missense	proximal	-1	no	8.792	8.459	EPSD;PhosphoSitePlus	CCLE	5.471	Down-regulation
TK_FGFR_FGFR1_Y	Q15118	PDK1	P11362	FGFR1	Y244	N246H	246	Missense	proximal	2	no	8.792	8.694	EPSD;PhosphoSitePlus	CCLE	5.471	Down-regulation
AGC_SGK_SGK3_ST	Q96J02	ITCH	Q96BR1	SGK3	T218	D222H	222	Missense	distal	4	no	4.879	4.851	EPSD	CCLE	2.112	Down-regulation
AGC_SGK_SGK3_ST	Q96J02	ITCH	Q96BR1	SGK3	T385	F380V	380	Missense	distal	-5	no	8.899	8.652	EPSD;PhosphoSitePlus	CCLE	2.112	Down-regulation
AGC_SGK_SGK3_ST	Q13045	FLII	Q96BR1	SGK3	S16	D19N	19	Missense	distal	3	no	2.255	1.667	EPSD	CCLE	2.112	Loss
AGC_SGK_SGK3_ST	Q13045	FLII	Q96BR1	SGK3	S16	V13M	13	Missense	distal	-3	no	2.255	2.458	EPSD	CCLE	2.112	Up-regulation
AGC_SGK_SGK3_ST	Q13045	FLII	Q96BR1	SGK3	T818	H812P	812	Missense	distal	-6	no	9.197	9.192	EPSD;PhosphoSitePlus	CCLE	2.112	Down-regulation
AGC_SGK_SGK3_ST	P49841	GSK3B	Q96BR1	SGK3	S147	T152M	152	Missense	distal	5	no	4.301	4.304	EPSD	CCLE	2.112	Up-regulation
Atypical_PIKK_ATM_ATM_ST	P25205	MCM3	Q13315	ATM	S160	V166M	166	Missense	distal	6	no	9.879	9.874	EPSD	CCLE	9.540	Down-regulation
Atypical_PIKK_ATM_ATM_ST	P25205	MCM3	Q13315	ATM	S535	N533I	533	Missense	proximal	-2	no	14.733	14.223	PhosphoSitePlus	CCLE	9.540	Down-regulation
Atypical_PIKK_ATM_ATM_ST	Q9NVI1	FANCI	Q13315	ATM	S726	D728G	728	Missense	proximal	2	no	11.387	10.148	EPSD	CCLE	9.540	Down-regulation
Atypical_PIKK_ATM_ATM_ST	Q9NVI1	FANCI	Q13315	ATM	S730	D728G	728	Missense	proximal	-2	no	16.945	16.801	EPSD;PhosphoSitePlus	CCLE	9.540	Down-regulation
Atypical_PIKK_ATM_ATM_ST	Q9NVI1	FANCI	Q13315	ATM	S1111	E1118D	1118	Missense	distal	7	no	15.807	15.819	EPSD	CCLE	9.540	Up-regulation
Atypical_PIKK_ATM_ATM_ST	Q9NVI1	FANCI	Q13315	ATM	S1121	E1118D	1118	Missense	distal	-3	no	15.858	16.263	EPSD;PhosphoSitePlus	CCLE	9.540	Up-regulation
Atypical_PIKK_ATM_ATM_ST	Q9NVI1	FANCI	Q13315	ATM	S1312	A1311S	1311	Missense	proximal	-1	no	10.278	10.438	EPSD	CCLE	9.540	Up-regulation
Atypical_PIKK_ATM_ATM_ST	Q99801	NKX3-1	Q13315	ATM	T166	E165A	165	Missense	proximal	-1	no	14.014	13.643	PhosphoSitePlus;EPSD	CCLE	9.540	Down-regulation
Atypical_PIKK_ATM_ATM_ST	Q12888	TP53BP1	Q13315	ATM	S25	E28A	28	Missense	distal	3	no	15.892	16.123	EPSD;PhosphoSitePlus	CCLE	9.540	Up-regulation
Atypical_PIKK_ATM_ATM_ST	Q12888	TP53BP1	Q13315	ATM	S29	E28A	28	Missense	proximal	-1	no	14.774	14.404	PhosphoSitePlus;EPSD	CCLE	9.540	Down-regulation
Atypical_PIKK_ATM_ATM_ST	Q12888	TP53BP1	Q13315	ATM	S259	M262R	262	Missense	distal	3	no	9.579	9.509	EPSD	CCLE	9.540	Loss
Atypical_PIKK_ATM_ATM_ST	Q12888	TP53BP1	Q13315	ATM	S380	T382S	382	Missense	proximal	2	no	9.831	10.093	EPSD	CCLE	9.540	Up-regulation
Atypical_PIKK_ATM_ATM_ST	Q12888	TP53BP1	Q13315	ATM	S452	S452P	452	Missense	central	0	yes	14.112	0.000	EPSD	CCLE	9.540	Loss
Atypical_PIKK_ATM_ATM_ST	Q12888	TP53BP1	Q13315	ATM	S523	L517H	517	Missense	distal	-6	no	14.307	14.415	EPSD	CCLE	9.540	Up-regulation
Atypical_PIKK_ATM_ATM_ST	Q12888	TP53BP1	Q13315	ATM	S784	S782L	782	Missense	proximal	-2	no	14.047	13.657	EPSD	CCLE	9.540	Down-regulation
Atypical_PIKK_ATM_ATM_ST	Q12888	TP53BP1	Q13315	ATM	T1273	T1270I	1270	Missense	distal	-3	no	9.816	10.554	EPSD	CCLE	9.540	Up-regulation
Atypical_PIKK_ATM_ATM_ST	Q12888	TP53BP1	Q13315	ATM	S1368	S1368R	1368	Missense	central	0	yes	14.035	0.000	EPSD	CCLE	9.540	Loss
Atypical_PIKK_ATM_ATM_ST	Q12888	TP53BP1	Q13315	ATM	S1368	V1367I	1367	Missense	proximal	-1	no	14.035	14.238	EPSD	CCLE	9.540	Up-regulation
Atypical_PIKK_ATM_ATM_ST	Q12888	TP53BP1	Q13315	ATM	S1635	V1633I	1633	Missense	proximal	-2	no	9.886	9.861	EPSD	CCLE	9.540	Down-regulation
Atypical_PIKK_ATM_ATM_ST	Q12888	TP53BP1	Q13315	ATM	S1656	R1658C	1658	Missense	proximal	2	no	10.215	9.959	EPSD	CCLE	9.540	Down-regulation
Atypical_PIKK_ATM_ATM_ST	Q12888	TP53BP1	Q13315	ATM	S1778	S1778C	1778	Missense	central	0	yes	12.854	0.000	EPSD;PhosphoSitePlus	CCLE	9.540	Loss
Atypical_PIKK_ATM_ATM_ST	P08047	SP1	Q13315	ATM	S698	R694C	694	Missense	distal	-4	no	9.855	9.092	EPSD	CCLE	9.540	Loss
Atypical_PIKK_ATM_ATM_ST	O95071	UBR5	Q13315	ATM	S117	F113L	113	Missense	distal	-4	no	9.782	10.241	EPSD	CCLE	9.540	Up-regulation
Atypical_PIKK_ATM_ATM_ST	Q92945	KHSRP	Q13315	ATM	S59	A55V	55	Missense	distal	-4	no	13.165	12.686	EPSD	CCLE	9.540	Down-regulation
Atypical_PIKK_ATM_ATM_ST	Q92945	KHSRP	Q13315	ATM	S274	V279M	279	Missense	distal	5	no	14.251	14.224	EPSD;PhosphoSitePlus	CCLE	9.540	Down-regulation
Atypical_PIKK_ATM_ATM_ST	Q92945	KHSRP	Q13315	ATM	S274	N278I	278	Missense	distal	4	no	14.251	14.787	EPSD;PhosphoSitePlus	CCLE	9.540	Up-regulation
Atypical_PIKK_ATM_ATM_ST	Q96S59	RANBP9	Q13315	ATM	S473	P478S	478	Missense	distal	5	no	9.935	9.753	EPSD	CCLE	9.540	Down-regulation
Atypical_PIKK_ATM_ATM_ST	O94916	NFAT5	Q13315	ATM	S238	H234Y	234	Missense	distal	-4	no	12.123	11.702	EPSD	CCLE	9.540	Down-regulation
Atypical_PIKK_ATM_ATM_ST	O94916	NFAT5	Q13315	ATM	T439	E446A	446	Missense	distal	7	no	13.708	13.743	EPSD	CCLE	9.540	Up-regulation
Atypical_PIKK_ATM_ATM_ST	O94916	NFAT5	Q13315	ATM	T631	S630L	630	Missense	proximal	-1	no	14.850	14.715	EPSD	CCLE	9.540	Down-regulation
Atypical_PIKK_ATM_ATM_ST	O94916	NFAT5	Q13315	ATM	S1247	A1240V	1240	Missense	distal	-7	no	14.424	14.040	EPSD;PhosphoSitePlus	CCLE	9.540	Down-regulation
Atypical_PIKK_ATM_ATM_ST	Q96SD1	DCLRE1C	Q13315	ATM	T91	T89A	89	Missense	proximal	-2	no	12.041	11.941	EPSD	CCLE	9.540	Down-regulation
Atypical_PIKK_ATM_ATM_ST	Q96SD1	DCLRE1C	Q13315	ATM	S553	V558G	558	Missense	distal	5	no	16.420	16.386	EPSD	CCLE	9.540	Down-regulation
Atypical_PIKK_ATM_ATM_ST	Q96SD1	DCLRE1C	Q13315	ATM	S562	V558G	558	Missense	distal	-4	no	15.649	15.850	EPSD	CCLE	9.540	Up-regulation
Atypical_PIKK_ATM_ATM_ST	Q7LG56	RRM2B	Q13315	ATM	S20	E26K	26	Missense	distal	6	no	9.872	9.826	EPSD	CCLE	9.540	Down-regulation
Atypical_PIKK_ATM_ATM_ST	Q7LG56	RRM2B	Q13315	ATM	S25	E26K	26	Missense	proximal	1	no	10.055	9.103	EPSD	CCLE	9.540	Loss
Atypical_PIKK_ATM_ATM_ST	Q9H2K8	TAOK3	Q13315	ATM	T419	S424G	424	Missense	distal	5	no	14.813	14.991	EPSD	CCLE	9.540	Up-regulation
Atypical_PIKK_ATM_ATM_ST	Q9H2K8	TAOK3	Q13315	ATM	S424	S424G	424	Missense	central	0	yes	13.670	0.000	EPSD	CCLE	9.540	Loss
Atypical_PIKK_ATM_ATM_ST	Q96RU2	USP28	Q13315	ATM	T491	T489K	489	Missense	proximal	-2	no	9.882	9.574	EPSD	CCLE	9.540	Down-regulation
Atypical_PIKK_ATM_ATM_ST	Q96RU2	USP28	Q13315	ATM	S495	T489K	489	Missense	distal	-6	no	15.523	15.479	PhosphoSitePlus;EPSD	CCLE	9.540	Down-regulation
Atypical_PIKK_ATM_ATM_ST	Q96RU2	USP28	Q13315	ATM	S856	D858N	858	Missense	proximal	2	no	11.522	10.500	EPSD	CCLE	9.540	Down-regulation
Atypical_PIKK_ATM_ATM_ST	Q96RU2	USP28	Q13315	ATM	S856	Q849E	849	Missense	distal	-7	no	11.522	12.076	EPSD	CCLE	9.540	Up-regulation
Atypical_PIKK_ATM_ATM_ST	Q96RU2	USP28	Q13315	ATM	S1053	D1056G	1056	Missense	distal	3	no	9.924	9.871	EPSD	CCLE	9.540	Down-regulation
Atypical_PIKK_ATM_ATM_ST	Q5TZA2	CROCC	Q13315	ATM	S512	D517G	517	Missense	distal	5	no	10.006	10.097	EPSD	CCLE	9.540	Up-regulation
Atypical_PIKK_ATM_ATM_ST	Q5TZA2	CROCC	Q13315	ATM	S830	Q831R	831	Missense	proximal	1	no	13.449	6.798	EPSD	CCLE	9.540	Loss
Atypical_PIKK_ATM_ATM_ST	Q5TZA2	CROCC	Q13315	ATM	T958	T958A	958	Missense	central	0	yes	13.100	0.000	EPSD	CCLE	9.540	Loss
Atypical_PIKK_ATM_ATM_ST	Q5TZA2	CROCC	Q13315	ATM	T958	K961T	961	Missense	distal	3	no	13.100	13.067	EPSD	CCLE	9.540	Down-regulation
Atypical_PIKK_ATM_ATM_ST	Q5TZA2	CROCC	Q13315	ATM	S1451	P1450S	1450	Missense	proximal	-1	no	9.973	10.265	EPSD	CCLE	9.540	Up-regulation
Atypical_PIKK_ATM_ATM_ST	Q5TZA2	CROCC	Q13315	ATM	S1451	P1454Q	1454	Missense	distal	3	no	9.973	9.904	EPSD	CCLE	9.540	Down-regulation
Atypical_PIKK_ATM_ATM_ST	Q5TZA2	CROCC	Q13315	ATM	S1460	P1454Q	1454	Missense	distal	-6	no	9.587	9.610	EPSD	CCLE	9.540	Up-regulation
Atypical_PIKK_ATM_ATM_ST	Q96J02	ITCH	Q13315	ATM	S18	K17T	17	Missense	proximal	-1	no	14.695	14.898	EPSD	CCLE	9.540	Up-regulation
Atypical_PIKK_ATM_ATM_ST	Q96J02	ITCH	Q13315	ATM	S18	S18P	18	Missense	central	0	yes	14.695	0.000	EPSD	CCLE	9.540	Loss
Atypical_PIKK_ATM_ATM_ST	Q96J02	ITCH	Q13315	ATM	S221	D222H	222	Missense	proximal	1	no	11.165	2.287	EPSD	CCLE	9.540	Loss
Atypical_PIKK_ATM_ATM_ST	Q96J02	ITCH	Q13315	ATM	S687	P682L	682	Missense	distal	-5	no	10.240	10.259	EPSD	CCLE	9.540	Up-regulation
Atypical_PIKK_ATM_ATM_ST	Q96J02	ITCH	Q13315	ATM	S687	Y685D	685	Missense	proximal	-2	no	10.240	10.111	EPSD	CCLE	9.540	Down-regulation
Atypical_PIKK_ATM_ATM_ST	Q9BXW9	FANCD2	Q13315	ATM	S29	K30E	30	Missense	proximal	1	no	9.046	9.998	EPSD	CCLE	9.540	Gain
Atypical_PIKK_ATM_ATM_ST	Q9BXW9	FANCD2	Q13315	ATM	S88	P87L	87	Missense	proximal	-1	no	9.648	9.805	EPSD	CCLE	9.540	Up-regulation
Atypical_PIKK_ATM_ATM_ST	Q9UQR1	ZNF148	Q13315	ATM	S306	S311P	311	Missense	distal	5	no	9.859	10.040	EPSD	CCLE	9.540	Up-regulation
Atypical_PIKK_ATM_ATM_ST	Q9UQR1	ZNF148	Q13315	ATM	T702	A699V	699	Missense	distal	-3	no	14.876	15.739	EPSD	CCLE	9.540	Up-regulation
Atypical_PIKK_ATM_ATM_ST	Q9UQR1	ZNF148	Q13315	ATM	S784	G790S	790	Missense	distal	6	no	13.254	13.273	EPSD	CCLE	9.540	Up-regulation
Atypical_PIKK_ATM_ATM_ST	Q96RL1	UIMC1	Q13315	ATM	T228	S224L	224	Missense	distal	-4	no	15.549	14.610	EPSD	CCLE	9.540	Down-regulation
Atypical_PIKK_ATM_ATM_ST	Q96RL1	UIMC1	Q13315	ATM	S653	G655A	655	Missense	proximal	2	no	9.382	9.658	EPSD	CCLE	9.540	Gain
Atypical_PIKK_ATM_ATM_ST	Q96T60	PNKP	Q13315	ATM	S364	S357F	357	Missense	distal	-7	no	10.302	9.472	EPSD	CCLE	9.540	Loss
Atypical_PIKK_ATM_ATM_ST	Q01094	E2F1	Q13315	ATM	S307	G309R	309	Missense	proximal	2	no	9.855	9.716	EPSD	CCLE	9.540	Down-regulation
Atypical_PIKK_ATM_ATM_ST	Q01094	E2F1	Q13315	ATM	S313	G309R	309	Missense	distal	-4	no	13.870	13.847	EPSD	CCLE	9.540	Down-regulation
Atypical_PIKK_ATM_ATM_ST	Q01094	E2F1	Q13315	ATM	S375	R373S	373	Missense	proximal	-2	no	9.644	10.087	EPSD	CCLE	9.540	Up-regulation
Atypical_PIKK_ATM_ATM_ST	Q00987	MDM2	Q13315	ATM	S395	S400N	400	Missense	distal	5	no	14.526	14.501	EPSD;PhosphoSitePlus	CCLE	9.540	Down-regulation
Atypical_PIKK_ATM_ATM_ST	Q00987	MDM2	Q13315	ATM	S407	S400N	400	Missense	distal	-7	no	16.962	16.776	PhosphoSitePlus;EPSD	CCLE	9.540	Down-regulation
Atypical_PIKK_ATM_ATM_ST	O96017	CHEK2	Q13315	ATM	S192	I189V	189	Missense	distal	-3	no	10.945	10.694	EPSD	CCLE	9.540	Down-regulation
Atypical_PIKK_ATM_ATM_ST	O96017	CHEK2	Q13315	ATM	S357	D361G	361	Missense	distal	4	no	14.674	14.596	EPSD	CCLE	9.540	Down-regulation
Atypical_PIKK_ATM_ATM_ST	O96017	CHEK2	Q13315	ATM	T432	S435L	435	Missense	distal	3	no	10.889	11.171	EPSD	CCLE	9.540	Up-regulation
Atypical_PIKK_ATM_ATM_ST	O96017	CHEK2	Q13315	ATM	S500	S505T	505	Missense	distal	5	no	11.027	11.010	EPSD	CCLE	9.540	Down-regulation
Atypical_PIKK_ATM_ATM_ST	Q8IY92	SLX4	Q13315	ATM	S467	Q474H	474	Missense	distal	7	no	11.693	11.712	EPSD	CCLE	9.540	Up-regulation
Atypical_PIKK_ATM_ATM_ST	Q8IY92	SLX4	Q13315	ATM	S476	Q474H	474	Missense	proximal	-2	no	10.448	10.145	EPSD	CCLE	9.540	Down-regulation
Atypical_PIKK_ATM_ATM_ST	Q8IY92	SLX4	Q13315	ATM	S601	S605N	605	Missense	distal	4	no	11.383	11.511	EPSD	CCLE	9.540	Up-regulation
Atypical_PIKK_ATM_ATM_ST	Q8IY92	SLX4	Q13315	ATM	S605	L612P	612	Missense	distal	7	no	13.778	13.777	EPSD	CCLE	9.540	Down-regulation
Atypical_PIKK_ATM_ATM_ST	Q8IY92	SLX4	Q13315	ATM	S605	S605N	605	Missense	central	0	yes	13.778	0.000	EPSD	CCLE	9.540	Loss
Atypical_PIKK_ATM_ATM_ST	Q8IY92	SLX4	Q13315	ATM	S1066	L1073S	1073	Missense	distal	7	no	12.570	12.550	EPSD	CCLE	9.540	Down-regulation
Atypical_PIKK_ATM_ATM_ST	Q8IY92	SLX4	Q13315	ATM	S1070	L1073S	1073	Missense	distal	3	no	9.715	9.433	EPSD	CCLE	9.540	Loss
Atypical_PIKK_ATM_ATM_ST	Q8IY92	SLX4	Q13315	ATM	T1288	Q1289H	1289	Missense	proximal	1	no	12.351	-2.558	EPSD	CCLE	9.540	Loss
Atypical_PIKK_ATM_ATM_ST	Q8IY92	SLX4	Q13315	ATM	S1355	P1361S	1361	Missense	distal	6	no	9.791	9.802	EPSD	CCLE	9.540	Up-regulation
Atypical_PIKK_ATM_ATM_ST	Q8IY92	SLX4	Q13315	ATM	S1453	R1456P	1456	Missense	distal	3	no	11.360	11.326	EPSD	CCLE	9.540	Down-regulation
Atypical_PIKK_ATM_ATM_ST	Q8IY92	SLX4	Q13315	ATM	S1455	A1462V	1462	Missense	distal	7	no	9.774	9.792	EPSD	CCLE	9.540	Up-regulation
Atypical_PIKK_ATM_ATM_ST	Q8IY92	SLX4	Q13315	ATM	S1455	R1456P	1456	Missense	proximal	1	no	9.774	11.624	EPSD	CCLE	9.540	Up-regulation
Atypical_PIKK_ATM_ATM_ST	P35637	FUS	Q13315	ATM	T7	Y14C	14	Missense	distal	7	no	11.741	11.760	EPSD	CCLE	9.540	Up-regulation
Atypical_PIKK_ATM_ATM_ST	P35637	FUS	Q13315	ATM	T11	Y14C	14	Missense	distal	3	no	11.965	12.144	EPSD	CCLE	9.540	Up-regulation
Atypical_PIKK_ATM_ATM_ST	P35637	FUS	Q13315	ATM	T19	Y14C	14	Missense	distal	-5	no	13.209	13.278	EPSD	CCLE	9.540	Up-regulation
Atypical_PIKK_ATM_ATM_ST	Q7Z6Z7	HUWE1	Q13315	ATM	S636	Y639S	639	Missense	distal	3	no	13.376	13.135	EPSD	CCLE	9.540	Down-regulation
Atypical_PIKK_ATM_ATM_ST	Q7Z6Z7	HUWE1	Q13315	ATM	T744	T744A	744	Missense	central	0	yes	15.443	0.000	EPSD	CCLE	9.540	Loss
Atypical_PIKK_ATM_ATM_ST	Q7Z6Z7	HUWE1	Q13315	ATM	S1218	N1211Y	1211	Missense	distal	-7	no	10.342	10.234	EPSD	CCLE	9.540	Down-regulation
Atypical_PIKK_ATM_ATM_ST	Q7Z6Z7	HUWE1	Q13315	ATM	S1370	M1369V	1369	Missense	proximal	-1	no	10.535	10.403	EPSD	CCLE	9.540	Down-regulation
Atypical_PIKK_ATM_ATM_ST	Q7Z6Z7	HUWE1	Q13315	ATM	S2850	T2846M	2846	Missense	distal	-4	no	12.588	11.964	EPSD	CCLE	9.540	Down-regulation
Atypical_PIKK_ATM_ATM_ST	Q7Z6Z7	HUWE1	Q13315	ATM	S2963	L2964F	2964	Missense	proximal	1	no	9.705	5.824	EPSD	CCLE	9.540	Loss
Atypical_PIKK_ATM_ATM_ST	Q7Z6Z7	HUWE1	Q13315	ATM	S3320	T3321P	3321	Missense	proximal	1	no	6.035	11.042	EPSD	CCLE	9.540	Gain
Atypical_PIKK_ATM_ATM_ST	Q7Z6Z7	HUWE1	Q13315	ATM	S3373	Q3378L	3378	Missense	distal	5	no	10.639	10.750	EPSD	CCLE	9.540	Up-regulation
Atypical_PIKK_ATM_ATM_ST	Q7Z6Z7	HUWE1	Q13315	ATM	S3377	Q3378L	3378	Missense	proximal	1	no	16.606	10.250	EPSD;PhosphoSitePlus	CCLE	9.540	Down-regulation
Atypical_PIKK_ATM_ATM_ST	Q7Z6Z7	HUWE1	Q13315	ATM	S3422	P3423A	3423	Missense	proximal	1	no	10.803	8.731	EPSD	CCLE	9.540	Loss
Atypical_PIKK_ATM_ATM_ST	Q7Z6Z7	HUWE1	Q13315	ATM	S4070	R4063G	4063	Missense	distal	-7	no	10.787	10.673	EPSD	CCLE	9.540	Down-regulation
Atypical_PIKK_ATM_ATM_ST	Q15648	MED1	Q13315	ATM	S387	R386L	386	Missense	proximal	-1	no	9.466	9.705	EPSD	CCLE	9.540	Gain
Atypical_PIKK_ATM_ATM_ST	Q15648	MED1	Q13315	ATM	S772	D773G	773	Missense	proximal	1	no	9.612	9.169	EPSD	CCLE	9.540	Loss
Atypical_PIKK_ATM_ATM_ST	Q15648	MED1	Q13315	ATM	S874	E881G	881	Missense	distal	7	no	15.554	15.599	EPSD;PhosphoSitePlus	CCLE	9.540	Up-regulation
Atypical_PIKK_ATM_ATM_ST	Q15648	MED1	Q13315	ATM	S887	E881G	881	Missense	distal	-6	no	16.742	16.353	EPSD;PhosphoSitePlus	CCLE	9.540	Down-regulation
Atypical_PIKK_ATM_ATM_ST	Q15648	MED1	Q13315	ATM	S1417	G1414R	1414	Missense	distal	-3	no	10.152	10.614	EPSD	CCLE	9.540	Up-regulation
Atypical_PIKK_ATM_ATM_ST	P07900	HSP90AA1	Q13315	ATM	S165	T171I	171	Missense	distal	6	no	9.812	9.781	EPSD	CCLE	9.540	Down-regulation
Atypical_PIKK_ATM_ATM_ST	P07900	HSP90AA1	Q13315	ATM	S165	A161V	161	Missense	distal	-4	no	9.812	9.332	EPSD	CCLE	9.540	Loss
Atypical_PIKK_ATM_ATM_ST	P07900	HSP90AA1	Q13315	ATM	S165	Q159R	159	Missense	distal	-6	no	9.812	9.668	EPSD	CCLE	9.540	Down-regulation
Atypical_PIKK_ATM_ATM_ST	P07900	HSP90AA1	Q13315	ATM	S252	E248K	248	Missense	distal	-4	no	9.817	8.845	EPSD	CCLE	9.540	Loss
Atypical_PIKK_ATM_ATM_ST	P07900	HSP90AA1	Q13315	ATM	S315	Y309C	309	Missense	distal	-6	no	11.255	11.124	EPSD	CCLE	9.540	Down-regulation
Atypical_PIKK_ATM_ATM_ST	P07900	HSP90AA1	Q13315	ATM	S595	L592S	592	Missense	distal	-3	no	11.393	11.184	EPSD	CCLE	9.540	Down-regulation
Atypical_PIKK_ATM_ATM_ST	Q9BQ15	NABP2	Q13315	ATM	T117	Y115H	115	Missense	proximal	-2	no	12.515	12.257	PhosphoSitePlus	CCLE	9.540	Down-regulation
Atypical_PIKK_ATM_ATM_ST	P38398	BRCA1	Q13315	ATM	S316	R315M	315	Missense	proximal	-1	no	14.757	14.840	EPSD	CCLE	9.540	Up-regulation
Atypical_PIKK_ATM_ATM_ST	P38398	BRCA1	Q13315	ATM	S1239	V1234L	1234	Missense	distal	-5	no	11.480	11.390	EPSD	CCLE	9.540	Down-regulation
Atypical_PIKK_ATM_ATM_ST	P38398	BRCA1	Q13315	ATM	S1330	M1324V	1324	Missense	distal	-6	no	14.179	14.167	EPSD	CCLE	9.540	Down-regulation
Atypical_PIKK_ATM_ATM_ST	Q96KQ7	EHMT2	Q13315	ATM	S391	S391F	391	Missense	central	0	yes	9.865	0.000	EPSD	CCLE	9.540	Loss
Atypical_PIKK_ATM_ATM_ST	Q99708	RBBP8	Q13315	ATM	S231	A236S	236	Missense	distal	5	no	13.801	13.753	EPSD	CCLE	9.540	Down-regulation
Atypical_PIKK_ATM_ATM_ST	Q99708	RBBP8	Q13315	ATM	S233	A236S	236	Missense	distal	3	no	11.621	11.565	EPSD	CCLE	9.540	Down-regulation
Atypical_PIKK_ATM_ATM_ST	Q99708	RBBP8	Q13315	ATM	S327	V325L	325	Missense	proximal	-2	no	10.777	11.052	EPSD	CCLE	9.540	Up-regulation
Atypical_PIKK_ATM_ATM_ST	Q99708	RBBP8	Q13315	ATM	S539	R536G	536	Missense	distal	-3	no	10.074	9.613	EPSD	CCLE	9.540	Down-regulation
Atypical_PIKK_ATM_ATM_ST	Q99708	RBBP8	Q13315	ATM	S568	P563A	563	Missense	distal	-5	no	11.175	11.163	EPSD	CCLE	9.540	Down-regulation
Atypical_PIKK_ATM_ATM_ST	O75150	RNF40	Q13315	ATM	S219	R212Q	212	Missense	distal	-7	no	10.983	11.182	EPSD	CCLE	9.540	Up-regulation
Atypical_PIKK_ATM_ATM_ST	O75150	RNF40	Q13315	ATM	S853	K860R	860	Missense	distal	7	no	13.618	13.630	PhosphoSitePlus;EPSD	CCLE	9.540	Up-regulation
Atypical_PIKK_ATM_ATM_ST	Q5VTR2	RNF20	Q13315	ATM	S28	D27N	27	Missense	proximal	-1	no	9.751	9.750	EPSD	CCLE	9.540	Down-regulation
Atypical_PIKK_ATM_ATM_ST	Q5VTR2	RNF20	Q13315	ATM	S172	R177H	177	Missense	distal	5	no	14.364	14.339	EPSD;PhosphoSitePlus	CCLE	9.540	Down-regulation
Atypical_PIKK_ATM_ATM_ST	Q5VTR2	RNF20	Q13315	ATM	S262	S255G	255	Missense	distal	-7	no	10.393	9.881	EPSD	CCLE	9.540	Down-regulation
Atypical_PIKK_ATM_ATM_ST	O15355	PPM1G	Q13315	ATM	S201	P200H	200	Missense	proximal	-1	no	14.556	14.644	EPSD	CCLE	9.540	Up-regulation
Atypical_PIKK_ATM_ATM_ST	Q14839	CHD4	Q13315	ATM	T529	A525V	525	Missense	distal	-4	no	9.715	9.236	EPSD	CCLE	9.540	Loss
Atypical_PIKK_ATM_ATM_ST	Q9NQS1	AVEN	Q13315	ATM	S135	R137K	137	Missense	proximal	2	no	13.656	13.834	EPSD;PhosphoSitePlus	CCLE	9.540	Up-regulation
Atypical_PIKK_ATM_ATM_ST	Q8TAQ5	ZNF420	Q13315	ATM	S376	I373F	373	Missense	distal	-3	no	12.568	12.970	EPSD	CCLE	9.540	Up-regulation
Atypical_PIKK_ATM_ATM_ST	Q8TAQ5	ZNF420	Q13315	ATM	S376	R374H	374	Missense	proximal	-2	no	12.568	12.583	EPSD	CCLE	9.540	Up-regulation
Atypical_PIKK_ATM_ATM_ST	Q8TAQ5	ZNF420	Q13315	ATM	S376	R383K	383	Missense	distal	7	no	12.568	12.556	EPSD	CCLE	9.540	Down-regulation
Atypical_PIKK_ATM_ATM_ST	Q9NS91	RAD18	Q13315	ATM	S146	R139G	139	Missense	distal	-7	no	11.295	11.181	EPSD	CCLE	9.540	Down-regulation
Atypical_PIKK_ATM_ATM_ST	P15927	RPA2	Q13315	ATM	S115	N117I	117	Missense	proximal	2	no	9.648	9.605	EPSD	CCLE	9.540	Down-regulation
Atypical_PIKK_ATM_ATM_ST	P15927	RPA2	Q13315	ATM	S115	S114N	114	Missense	proximal	-1	no	9.648	9.593	EPSD	CCLE	9.540	Down-regulation
Atypical_PIKK_ATM_ATM_ST	Q9UBU7	DBF4	Q13315	ATM	S381	Q382P	382	Missense	proximal	1	no	14.687	9.885	EPSD	CCLE	9.540	Down-regulation
Atypical_PIKK_ATM_ATM_ST	P41236	PPP1R2	Q13315	ATM	S44	Q45R	45	Missense	proximal	1	no	13.291	6.640	PhosphoSitePlus	CCLE	9.540	Loss
Atypical_PIKK_ATM_ATM_ST	Q14247	CTTN	Q13315	ATM	S113	S106L	106	Missense	distal	-7	no	14.639	14.051	PhosphoSitePlus	CCLE	9.540	Down-regulation
Atypical_PIKK_ATM_ATM_ST	Q9Y6D9	MAD1L1	Q13315	ATM	S185	Q188H	188	Missense	distal	3	no	9.557	9.698	EPSD	CCLE	9.540	Up-regulation
Atypical_PIKK_ATM_ATM_ST	P15374	UCHL3	Q13315	ATM	S75	K74T	74	Missense	proximal	-1	no	16.287	16.490	PhosphoSitePlus	CCLE	9.540	Up-regulation
Atypical_PIKK_ATM_ATM_ST	P15374	UCHL3	Q13315	ATM	S75	S75F	75	Missense	central	0	yes	16.287	0.000	PhosphoSitePlus	CCLE	9.540	Loss
Atypical_PIKK_ATM_ATM_ST	Q70CQ2	USP34	Q13315	ATM	S143	S142R	142	Missense	proximal	-1	no	9.892	9.517	EPSD	CCLE	9.540	Loss
Atypical_PIKK_ATM_ATM_ST	Q70CQ2	USP34	Q13315	ATM	S718	S721F	721	Missense	distal	3	no	15.869	16.451	EPSD;PhosphoSitePlus	CCLE	9.540	Up-regulation
Atypical_PIKK_ATM_ATM_ST	Q70CQ2	USP34	Q13315	ATM	S832	V836A	836	Missense	distal	4	no	12.174	11.521	EPSD	CCLE	9.540	Down-regulation
Atypical_PIKK_ATM_ATM_ST	Q70CQ2	USP34	Q13315	ATM	T3195	Q3194R	3194	Missense	proximal	-1	no	13.155	12.848	EPSD	CCLE	9.540	Down-regulation
Atypical_PIKK_ATM_ATM_ST	Q70CQ2	USP34	Q13315	ATM	T3350	P3351T	3351	Missense	proximal	1	no	10.611	5.604	EPSD	CCLE	9.540	Loss
Atypical_PIKK_ATM_ATM_ST	Q13769	THOC5	Q13315	ATM	S307	S312N	312	Missense	distal	5	no	13.722	13.697	EPSD;PhosphoSitePlus	CCLE	9.540	Down-regulation
Atypical_PIKK_ATM_ATM_ST	Q13315	ATM	Q13315	ATM	S200	V194A	194	Missense	distal	-6	no	14.132	14.368	EPSD	CCLE	9.540	Up-regulation
Atypical_PIKK_ATM_ATM_ST	Q13315	ATM	Q13315	ATM	S1981	S1987Y	1987	Missense	distal	6	no	14.545	14.504	EPSD;PhosphoSitePlus	CCLE	9.540	Down-regulation
Atypical_PIKK_ATM_ATM_ST	Q13315	ATM	Q13315	ATM	S2199	Y2202D	2202	Missense	distal	3	no	10.633	10.575	EPSD	CCLE	9.540	Down-regulation
Atypical_PIKK_ATM_ATM_ST	Q8N680	ZBTB2	Q13315	ATM	S203	P197R	197	Missense	distal	-6	no	10.550	10.428	EPSD	CCLE	9.540	Down-regulation
Atypical_PIKK_ATM_ATM_ST	Q7L7X3	TAOK1	Q13315	ATM	S554	N549T	549	Missense	distal	-5	no	14.335	14.274	EPSD	CCLE	9.540	Down-regulation
Atypical_PIKK_ATM_ATM_ST	P04637	TP53	Q13315	ATM	S106	G108V	108	Missense	proximal	2	no	10.952	10.919	EPSD	CCLE	9.540	Down-regulation
Atypical_PIKK_ATM_ATM_ST	O15111	CHUK	Q13315	ATM	S119	I121M	121	Missense	proximal	2	no	12.307	11.935	EPSD	CCLE	9.540	Down-regulation
Atypical_PIKK_ATM_ATM_ST	Q8IX03	WWC1	Q13315	ATM	S876	D880H	880	Missense	distal	4	no	12.923	12.832	EPSD	CCLE	9.540	Down-regulation
Atypical_PIKK_ATM_ATM_ST	P37275	ZEB1	Q13315	ATM	T162	F166C	166	Missense	distal	4	no	9.748	9.429	EPSD	CCLE	9.540	Loss
Atypical_PIKK_ATM_ATM_ST	P37275	ZEB1	Q13315	ATM	S167	F166C	166	Missense	proximal	-1	no	13.065	13.292	EPSD	CCLE	9.540	Up-regulation
Atypical_PIKK_ATM_ATM_ST	P37275	ZEB1	Q13315	ATM	T716	G718A	718	Missense	proximal	2	no	12.764	13.039	EPSD	CCLE	9.540	Up-regulation
Atypical_PIKK_ATM_ATM_ST	Q969R5	L3MBTL2	Q13315	ATM	S67	S67F	67	Missense	central	0	yes	12.995	0.000	EPSD	CCLE	9.540	Loss
Atypical_PIKK_ATM_ATM_ST	Q969R5	L3MBTL2	Q13315	ATM	S67	L71F	71	Missense	distal	4	no	12.995	13.481	EPSD	CCLE	9.540	Up-regulation
Atypical_PIKK_ATM_ATM_ST	Q969R5	L3MBTL2	Q13315	ATM	S73	S67F	67	Missense	distal	-6	no	10.322	9.791	EPSD	CCLE	9.540	Down-regulation
Atypical_PIKK_ATM_ATM_ST	Q969R5	L3MBTL2	Q13315	ATM	S73	L71F	71	Missense	proximal	-2	no	10.322	9.812	EPSD	CCLE	9.540	Down-regulation
Atypical_PIKK_ATM_ATM_ST	Q969R5	L3MBTL2	Q13315	ATM	T98	F102L	102	Missense	distal	4	no	9.638	9.152	EPSD	CCLE	9.540	Loss
Atypical_PIKK_ATM_ATM_ST	Q969R5	L3MBTL2	Q13315	ATM	S221	A223D	223	Missense	proximal	2	no	11.280	12.243	EPSD	CCLE	9.540	Up-regulation
Atypical_PIKK_ATM_ATM_ST	Q969R5	L3MBTL2	Q13315	ATM	S683	V681M	681	Missense	proximal	-2	no	9.759	9.986	EPSD	CCLE	9.540	Up-regulation
Atypical_PIKK_ATM_ATM_ST	Q969R5	L3MBTL2	Q13315	ATM	T703	D704N	704	Missense	proximal	1	no	9.580	5.750	EPSD	CCLE	9.540	Loss
Atypical_PIKK_ATM_ATM_ST	Q9Y4E8	USP15	Q13315	ATM	T11	A6G	6	Missense	distal	-5	no	11.376	11.438	EPSD	CCLE	9.540	Up-regulation
Atypical_PIKK_ATM_ATM_ST	Q9Y4E8	USP15	Q13315	ATM	T11	A7V	7	Missense	distal	-4	no	11.376	10.896	EPSD	CCLE	9.540	Down-regulation
Atypical_PIKK_ATM_ATM_ST	Q9Y4E8	USP15	Q13315	ATM	S355	S355I	355	Missense	central	0	yes	10.880	0.000	EPSD	CCLE	9.540	Loss
Atypical_PIKK_ATM_ATM_ST	Q9Y4E8	USP15	Q13315	ATM	S678	S678G	678	Missense	central	0	yes	16.513	0.000	PhosphoSitePlus	CCLE	9.540	Loss
Atypical_PIKK_ATM_ATM_ST	Q9Y2K7	KDM2A	Q13315	ATM	S394	R388W	388	Missense	distal	-6	no	10.277	10.109	EPSD	CCLE	9.540	Down-regulation
Atypical_PIKK_ATM_ATM_ST	Q9Y2K7	KDM2A	Q13315	ATM	S797	T800A	800	Missense	distal	3	no	9.600	9.575	EPSD	CCLE	9.540	Down-regulation
Atypical_PIKK_ATM_ATM_ST	Q9Y2K7	KDM2A	Q13315	ATM	S869	E872D	872	Missense	distal	3	no	11.030	11.389	EPSD	CCLE	9.540	Up-regulation
Atypical_PIKK_ATM_ATM_ST	Q02535	ID3	Q13315	ATM	S65	S65N	65	Missense	central	0	yes	14.211	0.000	PhosphoSitePlus	CCLE	9.540	Loss
Atypical_PIKK_ATM_ATM_ST	Q14683	SMC1A	Q13315	ATM	T182	D181G	181	Missense	proximal	-1	no	12.377	12.240	EPSD	CCLE	9.540	Down-regulation
Atypical_PIKK_ATM_ATM_ST	P54132	BLM	Q13315	ATM	S166	T162I	162	Missense	distal	-4	no	9.902	9.574	EPSD	CCLE	9.540	Down-regulation
Atypical_PIKK_ATM_ATM_ST	P54132	BLM	Q13315	ATM	S419	T412M	412	Missense	distal	-7	no	11.145	10.751	EPSD	CCLE	9.540	Down-regulation
Atypical_PIKK_ATM_ATM_ST	P54132	BLM	Q13315	ATM	S419	D420E	420	Missense	proximal	1	no	11.145	11.279	EPSD	CCLE	9.540	Up-regulation
Atypical_PIKK_ATM_ATM_ST	P54132	BLM	Q13315	ATM	S426	D420E	420	Missense	distal	-6	no	11.389	11.604	EPSD	CCLE	9.540	Up-regulation
Atypical_PIKK_ATM_ATM_ST	P54132	BLM	Q13315	ATM	S550	R545S	545	Missense	distal	-5	no	12.539	12.463	EPSD	CCLE	9.540	Down-regulation
Atypical_PIKK_ATM_ATM_ST	Q14190	SIM2	Q13315	ATM	S115	E118V	118	Missense	distal	3	no	11.783	12.303	PhosphoSitePlus	CCLE	9.540	Up-regulation
Atypical_PIKK_ATM_ATM_ST	Q14190	SIM2	Q13315	ATM	S186	L189S	189	Missense	distal	3	no	10.241	9.959	EPSD	CCLE	9.540	Down-regulation
Atypical_PIKK_ATM_ATM_ST	P54274	TERF1	Q13315	ATM	T24	M28I	28	Missense	distal	4	no	9.596	9.999	EPSD	CCLE	9.540	Up-regulation
Atypical_PIKK_ATM_ATM_ST	P54274	TERF1	Q13315	ATM	S404	Y398H	398	Missense	distal	-6	no	10.048	10.119	EPSD	CCLE	9.540	Up-regulation
Atypical_PIKK_ATM_ATM_ST	Q14161	GIT2	Q13315	ATM	T195	D197N	197	Missense	proximal	2	no	13.965	12.943	EPSD;PhosphoSitePlus	CCLE	9.540	Down-regulation
Atypical_PIKK_ATM_ATM_ST	Q14161	GIT2	Q13315	ATM	S634	P633R	633	Missense	proximal	-1	no	10.775	10.693	EPSD	CCLE	9.540	Down-regulation
Atypical_PIKK_ATM_ATM_ST	Q5XUX0	FBXO31	Q13315	ATM	S278	Y276C	276	Missense	proximal	-2	no	13.114	12.822	PhosphoSitePlus	CCLE	9.540	Down-regulation
Atypical_PIKK_ATM_ATM_ST	Q8WVD3	RNF138	Q13315	ATM	S124	I117V	117	Missense	distal	-7	no	14.483	14.667	PhosphoSitePlus	CCLE	9.540	Up-regulation
Atypical_PIKK_ATM_ATM_ST	P15336	ATF2	Q13315	ATM	T305	S307L	307	Missense	proximal	2	no	9.756	8.512	EPSD	CCLE	9.540	Loss
Atypical_PIKK_ATM_ATM_ST	P15336	ATF2	Q13315	ATM	S307	S307L	307	Missense	central	0	yes	10.402	0.000	EPSD	CCLE	9.540	Loss
Atypical_PIKK_ATM_ATM_ST	P15336	ATF2	Q13315	ATM	S328	A330G	330	Missense	proximal	2	no	10.429	10.154	EPSD	CCLE	9.540	Down-regulation
Atypical_PIKK_ATM_ATM_ST	P15336	ATF2	Q13315	ATM	T336	A330G	330	Missense	distal	-6	no	12.972	12.790	EPSD	CCLE	9.540	Down-regulation
Atypical_PIKK_ATM_ATM_ST	P15336	ATF2	Q13315	ATM	T485	E486Q	486	Missense	proximal	1	no	5.559	11.455	EPSD	CCLE	9.540	Gain
Atypical_PIKK_ATM_ATM_ST	P15336	ATF2	Q13315	ATM	S490	E486Q	486	Missense	distal	-4	no	15.398	14.675	PhosphoSitePlus;EPSD	CCLE	9.540	Down-regulation
Atypical_PIKK_ATM_ATM_ST	Q14676	MDC1	Q13315	ATM	T157	P159L	159	Missense	proximal	2	no	14.107	13.318	EPSD	CCLE	9.540	Down-regulation
Atypical_PIKK_ATM_ATM_ST	Q14676	MDC1	Q13315	ATM	T157	Q158L	158	Missense	proximal	1	no	14.107	7.751	EPSD	CCLE	9.540	Loss
Atypical_PIKK_ATM_ATM_ST	Q14676	MDC1	Q13315	ATM	S394	M398V	398	Missense	distal	4	no	15.205	15.250	EPSD	CCLE	9.540	Up-regulation
Atypical_PIKK_ATM_ATM_ST	Q14676	MDC1	Q13315	ATM	S422	E421D	421	Missense	proximal	-1	no	13.385	13.120	EPSD	CCLE	9.540	Down-regulation
Atypical_PIKK_ATM_ATM_ST	Q14676	MDC1	Q13315	ATM	S641	N644H	644	Missense	distal	3	no	9.770	9.793	EPSD	CCLE	9.540	Up-regulation
Atypical_PIKK_ATM_ATM_ST	Q14676	MDC1	Q13315	ATM	S882	E879G	879	Missense	distal	-3	no	9.638	10.075	EPSD	CCLE	9.540	Up-regulation
Atypical_PIKK_ATM_ATM_ST	Q14676	MDC1	Q13315	ATM	T946	K939R	939	Missense	distal	-7	no	12.717	12.630	EPSD	CCLE	9.540	Down-regulation
Atypical_PIKK_ATM_ATM_ST	Q14676	MDC1	Q13315	ATM	S988	R993M	993	Missense	distal	5	no	12.287	12.306	EPSD	CCLE	9.540	Up-regulation
Atypical_PIKK_ATM_ATM_ST	Q14676	MDC1	Q13315	ATM	S988	S981T	981	Missense	distal	-7	no	12.287	12.206	EPSD	CCLE	9.540	Down-regulation
Atypical_PIKK_ATM_ATM_ST	Q14676	MDC1	Q13315	ATM	S1143	S1148N	1148	Missense	distal	5	no	13.606	13.580	EPSD	CCLE	9.540	Down-regulation
Atypical_PIKK_ATM_ATM_ST	Q14676	MDC1	Q13315	ATM	T1403	V1408L	1408	Missense	distal	5	no	10.104	10.056	EPSD	CCLE	9.540	Down-regulation
Atypical_PIKK_ATM_ATM_ST	Q14676	MDC1	Q13315	ATM	S1430	P1426S	1426	Missense	distal	-4	no	13.024	13.694	EPSD	CCLE	9.540	Up-regulation
Atypical_PIKK_ATM_ATM_ST	Q14676	MDC1	Q13315	ATM	S1786	Q1787H	1787	Missense	proximal	1	no	12.057	-2.852	EPSD	CCLE	9.540	Loss
Atypical_PIKK_ATM_ATM_ST	Q9H7Z6	KAT8	Q13315	ATM	S42	P43S	43	Missense	proximal	1	no	11.225	4.250	EPSD	CCLE	9.540	Loss
Atypical_PIKK_ATM_ATM_ST	Q14694	USP10	Q13315	ATM	S331	S337I	337	Missense	distal	6	no	10.845	10.804	EPSD	CCLE	9.540	Down-regulation
Atypical_PIKK_ATM_ATM_ST	Q14694	USP10	Q13315	ATM	S337	S337I	337	Missense	central	0	yes	15.641	0.000	EPSD;PhosphoSitePlus	CCLE	9.540	Loss
Atypical_PIKK_ATM_ATM_ST	Q09472	EP300	Q13315	ATM	S106	A105T	105	Missense	proximal	-1	no	15.018	15.189	PhosphoSitePlus	CCLE	9.540	Up-regulation
Atypical_PIKK_ATM_ATM_ST	Q09472	EP300	Q13315	ATM	S384	M379T	379	Missense	distal	-5	no	9.803	9.629	EPSD	CCLE	9.540	Down-regulation
Atypical_PIKK_ATM_ATM_ST	Q09472	EP300	Q13315	ATM	T891	P888S	888	Missense	distal	-3	no	10.398	10.201	EPSD	CCLE	9.540	Down-regulation
Atypical_PIKK_ATM_ATM_ST	Q09472	EP300	Q13315	ATM	T992	P989S	989	Missense	distal	-3	no	12.510	12.313	EPSD	CCLE	9.540	Down-regulation
Atypical_PIKK_ATM_ATM_ST	Q09472	EP300	Q13315	ATM	T992	E999Q	999	Missense	distal	7	no	12.510	12.524	EPSD	CCLE	9.540	Up-regulation
Atypical_PIKK_ATM_ATM_ST	Q09472	EP300	Q13315	ATM	S1581	L1584Q	1584	Missense	distal	3	no	14.540	14.341	EPSD	CCLE	9.540	Down-regulation
Atypical_PIKK_ATM_ATM_ST	Q09472	EP300	Q13315	ATM	T1724	A1721V	1721	Missense	distal	-3	no	13.479	14.342	EPSD	CCLE	9.540	Up-regulation
Atypical_PIKK_ATM_ATM_ST	Q09472	EP300	Q13315	ATM	S1897	Q1898R	1898	Missense	proximal	1	no	12.874	6.222	EPSD	CCLE	9.540	Loss
Atypical_PIKK_ATM_ATM_ST	Q09472	EP300	Q13315	ATM	S1897	A1902V	1902	Missense	distal	5	no	12.874	13.038	EPSD	CCLE	9.540	Up-regulation
Atypical_PIKK_ATM_ATM_ST	Q92878	RAD50	Q13315	ATM	T536	T532I	532	Missense	distal	-4	no	11.201	10.872	EPSD	CCLE	9.540	Down-regulation
Atypical_PIKK_ATM_ATM_ST	Q92878	RAD50	Q13315	ATM	S1297	K1301R	1301	Missense	distal	4	no	9.876	9.978	EPSD	CCLE	9.540	Up-regulation
Atypical_PIKK_ATM_ATM_ST	Q13263	TRIM28	Q13315	ATM	S50	A44P	44	Missense	distal	-6	no	10.566	10.528	EPSD	CCLE	9.540	Down-regulation
Atypical_PIKK_ATM_ATM_ST	Q13263	TRIM28	Q13315	ATM	S50	A46S	46	Missense	distal	-4	no	10.566	11.076	EPSD	CCLE	9.540	Up-regulation
Atypical_PIKK_ATM_ATM_ST	Q13263	TRIM28	Q13315	ATM	S757	D764G	764	Missense	distal	7	no	9.585	9.618	EPSD	CCLE	9.540	Up-regulation
Atypical_PIKK_ATM_ATM_ST	O15151	MDM4	Q13315	ATM	S403	S400C	400	Missense	distal	-3	no	15.294	15.462	PhosphoSitePlus	CCLE	9.540	Up-regulation
Atypical_PIKK_ATM_ATM_ST	Q9H9Q4	NHEJ1	Q13315	ATM	S55	S52I	52	Missense	distal	-3	no	12.475	13.144	EPSD	CCLE	9.540	Up-regulation
Atypical_PIKK_ATM_ATM_ST	Q14191	WRN	Q13315	ATM	S453	D460G	460	Missense	distal	7	no	9.647	9.679	EPSD	CCLE	9.540	Up-regulation
Atypical_PIKK_ATM_ATM_ST	Q9UER7	DAXX	Q13315	ATM	S33	P29L	29	Missense	distal	-4	no	9.816	9.546	EPSD	CCLE	9.540	Down-regulation
Atypical_PIKK_ATM_ATM_ST	Q9UER7	DAXX	Q13315	ATM	S33	P29S	29	Missense	distal	-4	no	9.816	10.485	EPSD	CCLE	9.540	Up-regulation
Atypical_PIKK_ATM_ATM_ST	Q9UER7	DAXX	Q13315	ATM	S424	M422V	422	Missense	proximal	-2	no	15.255	15.029	EPSD	CCLE	9.540	Down-regulation
Atypical_PIKK_ATM_ATM_ST	Q9UER7	DAXX	Q13315	ATM	S688	S683Y	683	Missense	distal	-5	no	9.994	10.018	EPSD	CCLE	9.540	Up-regulation
Atypical_PIKK_ATM_ATM_ST	Q9UER7	DAXX	Q13315	ATM	S707	P701S	701	Missense	distal	-6	no	11.319	11.378	EPSD	CCLE	9.540	Up-regulation
Atypical_PIKK_ATM_ATM_ST	Q5UIP0	RIF1	Q13315	ATM	S143	I141L	141	Missense	proximal	-2	no	9.576	9.876	EPSD	CCLE	9.540	Up-regulation
Atypical_PIKK_ATM_ATM_ST	Q5UIP0	RIF1	Q13315	ATM	S467	S472P	472	Missense	distal	5	no	12.329	12.511	EPSD	CCLE	9.540	Up-regulation
Atypical_PIKK_ATM_ATM_ST	Q5UIP0	RIF1	Q13315	ATM	S1162	P1163S	1163	Missense	proximal	1	no	11.945	4.970	EPSD	CCLE	9.540	Loss
Atypical_PIKK_ATM_ATM_ST	Q5UIP0	RIF1	Q13315	ATM	S1403	S1403G	1403	Missense	central	0	yes	14.271	0.000	EPSD	CCLE	9.540	Loss
Atypical_PIKK_ATM_ATM_ST	Q5UIP0	RIF1	Q13315	ATM	S1542	S1548G	1548	Missense	distal	6	no	13.468	13.449	EPSD	CCLE	9.540	Down-regulation
Atypical_PIKK_ATM_ATM_ST	Q5UIP0	RIF1	Q13315	ATM	S1554	S1548G	1548	Missense	distal	-6	no	9.723	9.521	EPSD	CCLE	9.540	Loss
Atypical_PIKK_ATM_ATM_ST	Q5UIP0	RIF1	Q13315	ATM	S1554	S1557W	1557	Missense	distal	3	no	9.723	10.101	EPSD	CCLE	9.540	Up-regulation
Atypical_PIKK_ATM_ATM_ST	Q5UIP0	RIF1	Q13315	ATM	S1707	S1709L	1709	Missense	proximal	2	no	9.647	8.403	EPSD	CCLE	9.540	Loss
Atypical_PIKK_ATM_ATM_ST	Q5UIP0	RIF1	Q13315	ATM	S1709	S1709L	1709	Missense	central	0	yes	9.587	0.000	EPSD	CCLE	9.540	Loss
Atypical_PIKK_ATM_ATM_ST	Q5UIP0	RIF1	Q13315	ATM	S1873	S1873L	1873	Missense	central	0	yes	13.126	0.000	EPSD	CCLE	9.540	Loss
Atypical_PIKK_ATM_ATM_ST	Q5UIP0	RIF1	Q13315	ATM	S1873	Q1874H	1874	Missense	proximal	1	no	13.126	-1.783	EPSD	CCLE	9.540	Loss
Atypical_PIKK_ATM_ATM_ST	Q5UIP0	RIF1	Q13315	ATM	S2124	A2128V	2128	Missense	distal	4	no	14.155	14.808	EPSD	CCLE	9.540	Up-regulation
Atypical_PIKK_ATM_ATM_ST	Q5UIP0	RIF1	Q13315	ATM	S2129	A2128V	2128	Missense	proximal	-1	no	11.021	10.758	EPSD	CCLE	9.540	Down-regulation
Atypical_PIKK_ATM_ATM_ST	Q5UIP0	RIF1	Q13315	ATM	S2260	F2258C	2258	Missense	proximal	-2	no	10.283	10.722	EPSD	CCLE	9.540	Up-regulation
Atypical_PIKK_ATM_ATM_ST	Q5UIP0	RIF1	Q13315	ATM	S2465	N2458H	2458	Missense	distal	-7	no	13.660	13.534	EPSD	CCLE	9.540	Down-regulation
Atypical_PIKK_ATM_ATM_ST	Q13541	EIF4EBP1	Q13315	ATM	S94	R99C	99	Missense	distal	5	no	15.970	16.031	PhosphoSitePlus	CCLE	9.540	Up-regulation
Atypical_PIKK_ATM_ATM_ST	Q13541	EIF4EBP1	Q13315	ATM	S101	R99C	99	Missense	proximal	-2	no	12.020	12.000	EPSD	CCLE	9.540	Down-regulation
Atypical_PIKK_ATM_ATM_ST	O15164	TRIM24	Q13315	ATM	S35	R36Q	36	Missense	proximal	1	no	5.967	12.618	EPSD	CCLE	9.540	Gain
Atypical_PIKK_ATM_ATM_ST	O15164	TRIM24	Q13315	ATM	S41	R36Q	36	Missense	distal	-5	no	9.632	9.423	EPSD	CCLE	9.540	Loss
Atypical_PIKK_ATM_ATM_ST	O15164	TRIM24	Q13315	ATM	S41	R43S	43	Missense	proximal	2	no	9.632	10.630	EPSD	CCLE	9.540	Up-regulation
Atypical_PIKK_ATM_ATM_ST	O15164	TRIM24	Q13315	ATM	S41	E46K	46	Missense	distal	5	no	9.632	9.807	EPSD	CCLE	9.540	Up-regulation
Atypical_PIKK_ATM_ATM_ST	O15164	TRIM24	Q13315	ATM	S41	A48T	48	Missense	distal	7	no	9.632	9.618	EPSD	CCLE	9.540	Down-regulation
Atypical_PIKK_ATM_ATM_ST	O15164	TRIM24	Q13315	ATM	S41	A48S	48	Missense	distal	7	no	9.632	9.602	EPSD	CCLE	9.540	Down-regulation
Atypical_PIKK_ATM_ATM_ST	O15164	TRIM24	Q13315	ATM	S685	R684H	684	Missense	proximal	-1	no	9.650	9.820	EPSD	CCLE	9.540	Up-regulation
Atypical_PIKK_ATM_ATM_ST	O15164	TRIM24	Q13315	ATM	S1019	R1016G	1016	Missense	distal	-3	no	10.117	9.655	EPSD	CCLE	9.540	Down-regulation
Atypical_PIKK_ATM_ATM_ST	Q9NY61	AATF	Q13315	ATM	S104	D106Y	106	Missense	proximal	2	no	10.401	9.160	EPSD	CCLE	9.540	Loss
Atypical_PIKK_ATM_ATM_ST	Q9NY61	AATF	Q13315	ATM	S109	D106Y	106	Missense	distal	-3	no	9.710	9.597	EPSD	CCLE	9.540	Down-regulation
Atypical_PIKK_ATM_ATM_ST	Q9NY61	AATF	Q13315	ATM	T410	T410I	410	Missense	central	0	yes	11.972	0.000	EPSD	CCLE	9.540	Loss
Atypical_PIKK_ATM_ATM_ST	P51532	SMARCA4	Q13315	ATM	S610	L606V	606	Missense	distal	-4	no	13.887	13.837	EPSD	CCLE	9.540	Down-regulation
Atypical_PIKK_ATM_ATM_ST	P51532	SMARCA4	Q13315	ATM	S1452	N1454H	1454	Missense	proximal	2	no	9.638	9.598	EPSD	CCLE	9.540	Down-regulation
Atypical_PIKK_ATM_ATM_ST	Q03111	MLLT1	Q13315	ATM	S398	R403H	403	Missense	distal	5	no	15.392	15.366	PhosphoSitePlus;EPSD	CCLE	9.540	Down-regulation
Atypical_PIKK_ATM_ATM_ST	Q03111	MLLT1	Q13315	ATM	S411	D418N	418	Missense	distal	7	no	11.723	11.729	EPSD	CCLE	9.540	Up-regulation
Atypical_PIKK_ATM_ATM_ST	Q03111	MLLT1	Q13315	ATM	S414	D418N	418	Missense	distal	4	no	10.442	10.362	EPSD	CCLE	9.540	Down-regulation
Atypical_PIKK_ATM_ATM_ST	Q03111	MLLT1	Q13315	ATM	S421	D418N	418	Missense	distal	-3	no	10.097	9.824	EPSD	CCLE	9.540	Down-regulation
Atypical_PIKK_ATM_ATM_ST	Q8IZL8	PELP1	Q13315	ATM	S251	G253C	253	Missense	proximal	2	no	12.382	11.986	EPSD	CCLE	9.540	Down-regulation
Atypical_PIKK_ATM_ATM_ST	O14757	CHEK1	Q13315	ATM	S284	T279A	279	Missense	distal	-5	no	9.615	9.696	EPSD	CCLE	9.540	Up-regulation
Atypical_PIKK_ATM_ATM_ST	O14757	CHEK1	Q13315	ATM	S286	T279A	279	Missense	distal	-7	no	9.874	9.858	EPSD	CCLE	9.540	Down-regulation
Atypical_PIKK_ATM_ATM_ST	O14757	CHEK1	Q13315	ATM	S345	D351A	351	Missense	distal	6	no	13.959	13.987	PhosphoSitePlus	CCLE	9.540	Up-regulation
Atypical_PIKK_ATM_ATM_ST	O14757	CHEK1	Q13315	ATM	S357	D351A	351	Missense	distal	-6	no	11.736	11.742	EPSD	CCLE	9.540	Up-regulation
Atypical_PIKK_ATM_ATM_ST	O14757	CHEK1	Q13315	ATM	S357	Q358R	358	Missense	proximal	1	no	11.736	5.085	EPSD	CCLE	9.540	Loss
Atypical_PIKK_ATM_ATM_ST	Q01844	EWSR1	Q13315	ATM	T79	T75I	75	Missense	distal	-4	no	11.160	10.832	PhosphoSitePlus	CCLE	9.540	Down-regulation
Atypical_PIKK_ATM_ATM_ST	O43683	BUB1	Q13315	ATM	S331	P338Q	338	Missense	distal	7	no	14.645	14.636	EPSD	CCLE	9.540	Down-regulation
Atypical_PIKK_ATM_ATM_ST	O43683	BUB1	Q13315	ATM	S379	A372G	372	Missense	distal	-7	no	16.400	15.984	EPSD	CCLE	9.540	Down-regulation
Atypical_PIKK_ATM_ATM_ST	O43683	BUB1	Q13315	ATM	S596	L590M	590	Missense	distal	-6	no	10.601	10.644	EPSD	CCLE	9.540	Up-regulation
Atypical_PIKK_ATM_ATM_ST	O43683	BUB1	Q13315	ATM	S870	G872E	872	Missense	proximal	2	no	8.394	9.763	EPSD	CCLE	9.540	Gain
Atypical_PIKK_ATM_ATM_ST	O00213	APBB1	Q13315	ATM	S322	M327I	327	Missense	distal	5	no	9.628	9.653	EPSD	CCLE	9.540	Up-regulation
Atypical_PIKK_ATM_ATM_ST	O00213	APBB1	Q13315	ATM	S322	D323H	323	Missense	proximal	1	no	9.628	0.750	EPSD	CCLE	9.540	Loss
Atypical_PIKK_ATM_ATM_ST	Q86U86	PBRM1	Q13315	ATM	S10	A8T	8	Missense	proximal	-2	no	10.980	11.080	EPSD	CCLE	9.540	Up-regulation
Atypical_PIKK_ATM_ATM_ST	Q86U86	PBRM1	Q13315	ATM	S413	P407A	407	Missense	distal	-6	no	9.998	10.037	EPSD	CCLE	9.540	Up-regulation
Atypical_PIKK_ATM_ATM_ST	Q86U86	PBRM1	Q13315	ATM	S948	D950A	950	Missense	proximal	2	no	16.582	15.619	PhosphoSitePlus	CCLE	9.540	Down-regulation
Atypical_PIKK_ATM_ATM_ST	Q86U86	PBRM1	Q13315	ATM	S1116	R1120Q	1120	Missense	distal	4	no	10.171	10.023	EPSD	CCLE	9.540	Down-regulation
Atypical_PIKK_ATM_ATM_ST	Q86U86	PBRM1	Q13315	ATM	S1116	S1119N	1119	Missense	distal	3	no	10.171	10.372	EPSD	CCLE	9.540	Up-regulation
Atypical_PIKK_ATM_ATM_ST	Q86U86	PBRM1	Q13315	ATM	S1116	E1117D	1117	Missense	proximal	1	no	10.171	10.037	EPSD	CCLE	9.540	Down-regulation
Atypical_PIKK_ATM_ATM_ST	Q86U86	PBRM1	Q13315	ATM	S1116	D1114N	1114	Missense	proximal	-2	no	10.171	10.290	EPSD	CCLE	9.540	Up-regulation
Atypical_PIKK_ATM_ATM_ST	Q86U86	PBRM1	Q13315	ATM	S1119	R1120Q	1120	Missense	proximal	1	no	5.855	12.506	EPSD	CCLE	9.540	Gain
Atypical_PIKK_ATM_ATM_ST	Q86U86	PBRM1	Q13315	ATM	S1280	E1287Q	1287	Missense	distal	7	no	12.779	12.793	EPSD	CCLE	9.540	Up-regulation
Atypical_PIKK_ATM_ATM_ST	Q15797	SMAD1	Q13315	ATM	S239	T235A	235	Missense	distal	-4	no	14.556	14.430	PhosphoSitePlus	CCLE	9.540	Down-regulation
Atypical_PIKK_ATM_ATM_ST	Q15797	SMAD1	Q13315	ATM	S456	P460S	460	Missense	distal	4	no	10.020	9.897	EPSD	CCLE	9.540	Down-regulation
Atypical_PIKK_ATM_ATM_ST	P50542	PEX5	Q13315	ATM	S141	N136D	136	Missense	distal	-5	no	16.284	16.101	PhosphoSitePlus	CCLE	9.540	Down-regulation
Atypical_PIKK_ATM_ATM_ST	P50542	PEX5	Q13315	ATM	S141	S141A	141	Missense	central	0	yes	16.284	0.000	PhosphoSitePlus	CCLE	9.540	Loss
Atypical_PIKK_ATM_ATM_ST	P50542	PEX5	Q13315	ATM	S167	E168K	168	Missense	proximal	1	no	11.984	11.033	EPSD	CCLE	9.540	Down-regulation
Atypical_PIKK_ATM_ATM_ST	P50542	PEX5	Q13315	ATM	S228	I222V	222	Missense	distal	-6	no	10.826	10.970	EPSD	CCLE	9.540	Up-regulation
Atypical_PIKK_ATM_ATM_ST	P50542	PEX5	Q13315	ATM	S228	G232A	232	Missense	distal	4	no	10.826	10.350	EPSD	CCLE	9.540	Down-regulation
CMGC_MAPK_p38_MAPK13_ST	O00418	EEF2K	O15264	MAPK13	S359	S359C	359	Missense	central	0	yes	53.316	0.000	EPSD;PhosphoSitePlus	CCLE	38.013	Loss
CMGC_MAPK_p38_MAPK13_ST	O00418	EEF2K	O15264	MAPK13	T401	S404N	404	Missense	distal	3	no	46.484	46.267	EPSD	CCLE	38.013	Down-regulation
CMGC_MAPK_p38_MAPK13_ST	O00418	EEF2K	O15264	MAPK13	S404	S404N	404	Missense	central	0	yes	47.258	0.000	EPSD	CCLE	38.013	Loss
CMGC_MAPK_p38_MAPK13_ST	P10636	MAPT	O15264	MAPK13	T69	A66V	66	Missense	distal	-3	no	55.747	56.787	EPSD	CCLE	38.013	Up-regulation
CMGC_MAPK_p38_MAPK13_ST	P10636	MAPT	O15264	MAPK13	T111	G107V	107	Missense	distal	-4	no	38.311	39.495	EPSD	CCLE	38.013	Up-regulation
CMGC_MAPK_p38_MAPK13_ST	P10636	MAPT	O15264	MAPK13	S228	D221Y	221	Missense	distal	-7	no	46.272	45.996	EPSD	CCLE	38.013	Down-regulation
CMGC_MAPK_p38_MAPK13_ST	P10636	MAPT	O15264	MAPK13	S228	P234S	234	Missense	distal	6	no	46.272	46.335	EPSD	CCLE	38.013	Up-regulation
CMGC_MAPK_p38_MAPK13_ST	P10636	MAPT	O15264	MAPK13	S232	P234S	234	Missense	proximal	2	no	50.046	50.488	EPSD	CCLE	38.013	Up-regulation
CMGC_MAPK_p38_MAPK13_ST	P10636	MAPT	O15264	MAPK13	S238	P234S	234	Missense	distal	-4	no	52.512	53.521	EPSD	CCLE	38.013	Up-regulation
CMGC_MAPK_p38_MAPK13_ST	P10636	MAPT	O15264	MAPK13	S238	D242H	242	Missense	distal	4	no	52.512	52.516	EPSD	CCLE	38.013	Up-regulation
CMGC_MAPK_p38_MAPK13_ST	P10636	MAPT	O15264	MAPK13	T403	K405R	405	Missense	proximal	2	no	39.010	40.538	EPSD	CCLE	38.013	Up-regulation
CMGC_MAPK_p38_MAPK13_ST	P10636	MAPT	O15264	MAPK13	S411	K405R	405	Missense	distal	-6	no	52.055	52.084	EPSD	CCLE	38.013	Up-regulation
CMGC_MAPK_p38_MAPK13_ST	P10636	MAPT	O15264	MAPK13	S438	V442I	442	Missense	distal	4	no	49.548	48.878	EPSD	CCLE	38.013	Down-regulation
CMGC_MAPK_p38_MAPK13_ST	P10636	MAPT	O15264	MAPK13	S447	V442I	442	Missense	distal	-5	no	43.110	43.612	EPSD	CCLE	38.013	Up-regulation
CMGC_MAPK_p38_MAPK13_ST	P10636	MAPT	O15264	MAPK13	S516	R511H	511	Missense	distal	-5	no	57.896	58.361	EPSD	CCLE	38.013	Up-regulation
CMGC_MAPK_p38_MAPK13_ST	P10636	MAPT	O15264	MAPK13	S516	G518S	518	Missense	proximal	2	no	57.896	58.943	EPSD	CCLE	38.013	Up-regulation
CMGC_MAPK_p38_MAPK13_ST	P10636	MAPT	O15264	MAPK13	S519	G518S	518	Missense	proximal	-1	no	62.266	62.708	EPSD	CCLE	38.013	Up-regulation
CMGC_MAPK_p38_MAPK13_ST	P10636	MAPT	O15264	MAPK13	S519	R526L	526	Missense	distal	7	no	62.266	61.381	EPSD	CCLE	38.013	Down-regulation
CMGC_MAPK_p38_MAPK13_ST	P10636	MAPT	O15264	MAPK13	T522	G518S	518	Missense	distal	-4	no	58.788	61.334	EPSD	CCLE	38.013	Up-regulation
CMGC_MAPK_p38_MAPK13_ST	P10636	MAPT	O15264	MAPK13	T522	R526L	526	Missense	distal	4	no	58.788	58.069	EPSD	CCLE	38.013	Down-regulation
CMGC_MAPK_p38_MAPK13_ST	P10636	MAPT	O15264	MAPK13	S525	G518S	518	Missense	distal	-7	no	42.544	41.886	EPSD	CCLE	38.013	Down-regulation
CMGC_MAPK_p38_MAPK13_ST	P10636	MAPT	O15264	MAPK13	S525	R526L	526	Missense	proximal	1	no	42.544	42.159	EPSD	CCLE	38.013	Down-regulation
CMGC_MAPK_p38_MAPK13_ST	P10636	MAPT	O15264	MAPK13	S527	R526L	526	Missense	proximal	-1	no	43.486	42.694	EPSD	CCLE	38.013	Down-regulation
CMGC_MAPK_p38_MAPK13_ST	P10636	MAPT	O15264	MAPK13	T529	R526L	526	Missense	distal	-3	no	61.630	60.721	EPSD	CCLE	38.013	Down-regulation
CMGC_MAPK_p38_MAPK13_ST	P10636	MAPT	O15264	MAPK13	S531	R526L	526	Missense	distal	-5	no	47.793	48.364	EPSD	CCLE	38.013	Up-regulation
CMGC_MAPK_p38_MAPK13_ST	P10636	MAPT	O15264	MAPK13	S552	R559H	559	Missense	distal	7	no	60.759	60.310	EPSD	CCLE	38.013	Down-regulation
CMGC_MAPK_p38_MAPK13_ST	P10636	MAPT	O15264	MAPK13	S558	R559H	559	Missense	proximal	1	no	40.639	24.302	EPSD	CCLE	38.013	Loss
CMGC_MAPK_p38_MAPK13_ST	P10636	MAPT	O15264	MAPK13	S713	G706V	706	Missense	distal	-7	no	51.455	50.064	EPSD	CCLE	38.013	Down-regulation
CMGC_MAPK_p38_MAPK13_ST	P10636	MAPT	O15264	MAPK13	S713	S717C	717	Missense	distal	4	no	51.455	49.357	EPSD	CCLE	38.013	Down-regulation
CMGC_MAPK_p38_MAPK13_ST	P10636	MAPT	O15264	MAPK13	S721	S717C	717	Missense	distal	-4	no	55.304	50.660	EPSD	CCLE	38.013	Down-regulation
CMGC_MAPK_p38_MAPK13_ST	P10636	MAPT	O15264	MAPK13	S721	S721C	721	Missense	central	0	yes	55.304	0.000	EPSD	CCLE	38.013	Loss
CMGC_MAPK_p38_MAPK13_ST	P10636	MAPT	O15264	MAPK13	S721	H724R	724	Missense	distal	3	no	55.304	55.376	EPSD	CCLE	38.013	Up-regulation
CMGC_MAPK_p38_MAPK13_ST	P10636	MAPT	O15264	MAPK13	S726	S721C	721	Missense	distal	-5	no	38.862	39.902	EPSD	CCLE	38.013	Up-regulation
CMGC_MAPK_p38_MAPK13_ST	P10636	MAPT	O15264	MAPK13	S726	H724R	724	Missense	proximal	-2	no	38.862	39.649	EPSD	CCLE	38.013	Up-regulation
CMGC_MAPK_p38_MAPK13_ST	P10636	MAPT	O15264	MAPK13	S739	Q741K	741	Missense	proximal	2	no	54.284	54.346	EPSD	CCLE	38.013	Up-regulation
CMGC_MAPK_p38_MAPK13_ST	Q00613	HSF1	O15264	MAPK13	S244	P243L	243	Missense	proximal	-1	no	43.089	42.456	EPSD	CCLE	38.013	Down-regulation
CMGC_MAPK_p38_MAPK13_ST	Q00613	HSF1	O15264	MAPK13	S292	R287M	287	Missense	distal	-5	no	41.730	42.187	EPSD	CCLE	38.013	Up-regulation
CMGC_MAPK_p38_MAPK13_ST	Q00613	HSF1	O15264	MAPK13	T369	E371K	371	Missense	proximal	2	no	44.201	45.271	EPSD	CCLE	38.013	Up-regulation
CMGC_MAPK_p38_MAPK13_ST	Q00613	HSF1	O15264	MAPK13	S375	E371K	371	Missense	distal	-4	no	35.962	38.410	EPSD	CCLE	38.013	Gain
CMGC_MAPK_p38_MAPK13_ST	Q00613	HSF1	O15264	MAPK13	S419	V424M	424	Missense	distal	5	no	52.329	52.105	EPSD	CCLE	38.013	Down-regulation
CMGC_MAPK_p38_MAPK13_ST	Q13501	SQSTM1	O15264	MAPK13	S170	P171L	171	Missense	proximal	1	no	44.023	31.591	EPSD	CCLE	38.013	Loss
CMGC_MAPK_p38_MAPK13_ST	Q13501	SQSTM1	O15264	MAPK13	S284	K281R	281	Missense	distal	-3	no	43.411	43.393	EPSD	CCLE	38.013	Down-regulation
CMGC_MAPK_p38_MAPK13_ST	Q13501	SQSTM1	O15264	MAPK13	S306	E309K	309	Missense	distal	3	no	41.052	41.520	EPSD	CCLE	38.013	Up-regulation
CMGC_MAPK_p38_MAPK13_ST	Q13501	SQSTM1	O15264	MAPK13	S355	S361F	361	Missense	distal	6	no	40.187	39.683	EPSD	CCLE	38.013	Down-regulation
CMGC_MAPK_p38_MAPK13_ST	P30281	CCND3	O15264	MAPK13	S259	S259F	259	Missense	central	0	yes	43.189	0.000	EPSD	CCLE	38.013	Loss
CMGC_MAPK_p38_MAPK13_ST	P30281	CCND3	O15264	MAPK13	S264	S259F	259	Missense	distal	-5	no	54.196	54.925	EPSD	CCLE	38.013	Up-regulation
STE_STE20_NinaC_MYO3A_ST	Q8NEV4	MYO3A	Q8NEV4	MYO3A	T178	S177R	177	Missense	proximal	-1	no	9.069	9.117	EPSD;PhosphoSitePlus	CCLE	3.030	Up-regulation
STE_STE20_NinaC_MYO3A_ST	Q8NEV4	MYO3A	Q8NEV4	MYO3A	T184	S177R	177	Missense	distal	-7	no	8.742	8.831	EPSD;PhosphoSitePlus	CCLE	3.030	Up-regulation
STE_STE20_NinaC_MYO3A_ST	Q8NEV4	MYO3A	Q8NEV4	MYO3A	S335	I334L	334	Missense	proximal	-1	no	3.416	3.108	EPSD	CCLE	3.030	Down-regulation
STE_STE20_NinaC_MYO3A_ST	Q8NEV4	MYO3A	Q8NEV4	MYO3A	T908	R913H	913	Missense	distal	5	no	8.285	8.291	EPSD;PhosphoSitePlus	CCLE	3.030	Up-regulation
STE_STE20_NinaC_MYO3A_ST	Q8NEV4	MYO3A	Q8NEV4	MYO3A	T919	R913H	913	Missense	distal	-6	no	9.799	9.664	PhosphoSitePlus;EPSD	CCLE	3.030	Down-regulation
STE_STE20_NinaC_MYO3A_ST	Q8NEV4	MYO3A	Q8NEV4	MYO3A	T919	K922E	922	Missense	distal	3	no	9.799	9.785	PhosphoSitePlus;EPSD	CCLE	3.030	Down-regulation
TK_Src_SrcA_FYN_Y	Q12879	GRIN2A	P06241	FYN	Y1187	Y1184C	1184	Missense	distal	-3	no	4.093	1.014	EPSD;PhosphoSitePlus	CCLE	3.469	Loss
TK_Src_SrcA_FYN_Y	Q12879	GRIN2A	P06241	FYN	Y1267	A1272T	1272	Missense	distal	5	no	7.932	7.255	EPSD;PhosphoSitePlus	CCLE	3.469	Down-regulation
TK_Src_SrcA_FYN_Y	Q96J02	ITCH	P06241	FYN	Y375	M371I	371	Missense	distal	-4	no	4.683	3.626	EPSD	CCLE	3.469	Down-regulation
TK_Src_SrcA_FYN_Y	Q96J02	ITCH	P06241	FYN	Y375	G372R	372	Missense	distal	-3	no	4.683	3.447	EPSD	CCLE	3.469	Loss
TK_Src_SrcA_FYN_Y	Q96J02	ITCH	P06241	FYN	Y375	F380V	380	Missense	distal	5	no	4.683	4.517	EPSD	CCLE	3.469	Down-regulation
TK_Src_SrcA_FYN_Y	Q96J02	ITCH	P06241	FYN	Y420	F418L	418	Missense	proximal	-2	no	4.897	4.660	PhosphoSitePlus	CCLE	3.469	Down-regulation
TK_Src_SrcA_FYN_Y	P06127	CD5	P06241	FYN	Y487	D480G	480	Missense	distal	-7	no	3.992	3.329	EPSD;PhosphoSitePlus	CCLE	3.469	Loss
TK_Src_SrcA_FYN_Y	P16885	PLCG2	P06241	FYN	Y759	I765V	765	Missense	distal	6	no	3.649	3.155	EPSD;PhosphoSitePlus	CCLE	3.469	Loss
TK_Src_SrcA_FYN_Y	P00519	ABL1	P06241	FYN	Y115	P112S	112	Missense	distal	-3	no	3.603	4.161	EPSD;PhosphoSitePlus	CCLE	3.469	Up-regulation
TK_Src_SrcA_FYN_Y	P00519	ABL1	P06241	FYN	Y128	R134C	134	Missense	distal	6	no	4.824	5.526	EPSD;PhosphoSitePlus	CCLE	3.469	Up-regulation
TK_Src_SrcA_FYN_Y	P00519	ABL1	P06241	FYN	Y139	R134C	134	Missense	distal	-5	no	6.772	6.210	EPSD;PhosphoSitePlus	CCLE	3.469	Down-regulation
TK_Src_SrcA_FYN_Y	P00519	ABL1	P06241	FYN	Y139	A137T	137	Missense	proximal	-2	no	6.772	6.660	EPSD;PhosphoSitePlus	CCLE	3.469	Down-regulation
TK_Src_SrcA_FYN_Y	P00519	ABL1	P06241	FYN	Y172	A179V	179	Missense	distal	7	no	8.367	8.322	EPSD;PhosphoSitePlus	CCLE	3.469	Down-regulation
TK_Src_SrcA_FYN_Y	P00519	ABL1	P06241	FYN	Y185	A179V	179	Missense	distal	-6	no	4.806	4.869	EPSD;PhosphoSitePlus	CCLE	3.469	Up-regulation
TK_Src_SrcA_FYN_Y	P00519	ABL1	P06241	FYN	Y215	Y215H	215	Missense	central	0	yes	4.580	0.000	EPSD;PhosphoSitePlus	CCLE	3.469	Loss
TK_Src_SrcA_FYN_Y	P00519	ABL1	P06241	FYN	Y1064	G1060D	1060	Missense	distal	-4	no	1.573	3.929	EPSD	CCLE	3.469	Gain
TK_Src_SrcA_FYN_Y	O75051	PLXNA2	P06241	FYN	Y1605	V1598F	1598	Missense	distal	-7	no	5.922	4.396	PhosphoSitePlus;EPSD	CCLE	3.469	Down-regulation
TK_Src_SrcA_FYN_Y	Q01628	IFITM3	P06241	FYN	Y20	P17H	17	Missense	distal	-3	no	4.247	4.636	PhosphoSitePlus	CCLE	3.469	Up-regulation
TK_Src_SrcA_FYN_Y	P52757	CHN2	P06241	FYN	Y55	G62V	62	Missense	distal	7	no	3.943	3.922	EPSD	CCLE	3.469	Down-regulation
TK_Src_SrcA_FYN_Y	P52757	CHN2	P06241	FYN	Y153	T160A	160	Missense	distal	7	no	6.106	6.118	EPSD	CCLE	3.469	Up-regulation
TK_Src_SrcA_FYN_Y	O14559	ARHGAP33	P06241	FYN	Y406	Q404K	404	Missense	proximal	-2	no	6.581	6.147	PhosphoSitePlus	CCLE	3.469	Down-regulation
TK_Src_SrcA_FYN_Y	Q14194	CRMP1	P06241	FYN	Y499	G497S	497	Missense	proximal	-2	no	3.530	3.245	EPSD	CCLE	3.469	Loss
TK_Src_SrcA_FYN_Y	Q14194	CRMP1	P06241	FYN	Y504	G497S	497	Missense	distal	-7	no	6.638	6.965	PhosphoSitePlus	CCLE	3.469	Up-regulation
TK_Src_SrcA_FYN_Y	Q9UIW2	PLXNA1	P06241	FYN	Y159	L160M	160	Missense	proximal	1	no	3.743	2.772	EPSD	CCLE	3.469	Loss
TK_Src_SrcA_FYN_Y	Q9UIW2	PLXNA1	P06241	FYN	Y159	V163M	163	Missense	distal	4	no	3.743	3.905	EPSD	CCLE	3.469	Up-regulation
TK_Src_SrcA_FYN_Y	Q9UIW2	PLXNA1	P06241	FYN	Y1097	M1102V	1102	Missense	distal	5	no	4.910	4.737	EPSD	CCLE	3.469	Down-regulation
TK_Src_SrcA_FYN_Y	Q9UIW2	PLXNA1	P06241	FYN	Y1679	K1673E	1673	Missense	distal	-6	no	5.272	4.938	PhosphoSitePlus;EPSD	CCLE	3.469	Down-regulation
TK_Src_SrcA_FYN_Y	P11137	MAP2	P06241	FYN	Y50	R43Q	43	Missense	distal	-7	no	6.379	6.123	EPSD;PhosphoSitePlus	CCLE	3.469	Down-regulation
TK_Src_SrcA_FYN_Y	P11137	MAP2	P06241	FYN	Y50	G56V	56	Missense	distal	6	no	6.379	6.320	EPSD;PhosphoSitePlus	CCLE	3.469	Down-regulation
TK_Src_SrcA_FYN_Y	P11137	MAP2	P06241	FYN	Y67	N69D	69	Missense	proximal	2	no	5.132	5.014	PhosphoSitePlus;EPSD	CCLE	3.469	Down-regulation
TK_Src_SrcA_FYN_Y	P11137	MAP2	P06241	FYN	Y637	Q642H	642	Missense	distal	5	no	5.182	4.455	EPSD	CCLE	3.469	Down-regulation
TK_Src_SrcA_FYN_Y	Q14247	CTTN	P06241	FYN	Y162	F158V	158	Missense	distal	-4	no	3.391	5.317	EPSD	CCLE	3.469	Gain
TK_Src_SrcA_FYN_Y	O43294	TGFB1I1	P06241	FYN	Y38	S37P	37	Missense	proximal	-1	no	2.963	4.634	EPSD	CCLE	3.469	Gain
TK_Src_SrcA_FYN_Y	P06241	FYN	P06241	FYN	Y185	L187H	187	Missense	proximal	2	no	6.198	6.157	EPSD;PhosphoSitePlus	CCLE	3.469	Down-regulation
TK_Src_SrcA_FYN_Y	Q12913	PTPRJ	P06241	FYN	Y1058	S1054N	1054	Missense	distal	-4	no	3.085	3.702	EPSD	CCLE	3.469	Gain
TK_Src_SrcA_FYN_Y	P49023	PXN	P06241	FYN	Y181	S178N	178	Missense	distal	-3	no	4.438	5.198	EPSD	CCLE	3.469	Up-regulation
TK_Src_SrcA_FYN_Y	O14522	PTPRT	P06241	FYN	Y1008	P1002Q	1002	Missense	distal	-6	no	7.020	7.448	EPSD	CCLE	3.469	Up-regulation
TK_Src_SrcA_FYN_Y	P40763	STAT3	P06241	FYN	Y446	H447R	447	Missense	proximal	1	no	4.534	3.383	EPSD	CCLE	3.469	Loss
TK_Src_SrcA_FYN_Y	P40763	STAT3	P06241	FYN	Y539	T545I	545	Missense	distal	6	no	3.017	3.566	EPSD	CCLE	3.469	Gain
TK_Src_SrcA_FYN_Y	Q06124	PTPN11	P06241	FYN	Y304	N298S	298	Missense	distal	-6	no	3.867	4.238	EPSD	CCLE	3.469	Up-regulation
TK_Src_SrcA_FYN_Y	Q9NZA1	CLIC5	P06241	FYN	Y33	S30T	30	Missense	distal	-3	no	7.553	8.257	PhosphoSitePlus	CCLE	3.469	Up-regulation
TK_Src_SrcA_FYN_Y	P10636	MAPT	P06241	FYN	Y514	R511H	511	Missense	distal	-3	no	3.418	3.795	EPSD	CCLE	3.469	Gain
TK_Src_SrcA_FYN_Y	P10636	MAPT	P06241	FYN	Y514	G518S	518	Missense	distal	4	no	3.418	3.593	EPSD	CCLE	3.469	Gain
TK_Src_SrcA_FYN_Y	P78352	DLG4	P06241	FYN	Y523	V526M	526	Missense	distal	3	no	5.978	5.494	PhosphoSitePlus	CCLE	3.469	Down-regulation
Other_TTK_TTK_ST	Q9Y5T5	USP16	P33981	TTK	S552	T550S	550	Missense	proximal	-2	no	22.936	22.581	EPSD;PhosphoSitePlus	CCLE	18.469	Down-regulation
Other_TTK_TTK_ST	Q9Y5T5	USP16	P33981	TTK	T554	T550S	550	Missense	distal	-4	no	21.399	21.340	EPSD;PhosphoSitePlus	CCLE	18.469	Down-regulation
Other_TTK_TTK_ST	P33981	TTK	P33981	TTK	S49	T45N	45	Missense	distal	-4	no	19.054	19.004	EPSD	CCLE	18.469	Down-regulation
Other_TTK_TTK_ST	P33981	TTK	P33981	TTK	S80	L87F	87	Missense	distal	7	no	24.126	22.745	EPSD;PhosphoSitePlus	CCLE	18.469	Down-regulation
Other_TTK_TTK_ST	P33981	TTK	P33981	TTK	T210	A211T	211	Missense	proximal	1	no	20.797	20.828	EPSD	CCLE	18.469	Up-regulation
Other_TTK_TTK_ST	P33981	TTK	P33981	TTK	T288	K287N	287	Missense	proximal	-1	no	20.915	22.038	EPSD;PhosphoSitePlus	CCLE	18.469	Up-regulation
Other_TTK_TTK_ST	P33981	TTK	P33981	TTK	S582	D583N	583	Missense	proximal	1	no	20.360	20.355	EPSD;PhosphoSitePlus	CCLE	18.469	Down-regulation
Other_TTK_TTK_ST	P07900	HSP90AA1	P33981	TTK	T109	G108D	108	Missense	proximal	-1	no	22.269	22.615	EPSD	CCLE	18.469	Up-regulation
Other_TTK_TTK_ST	P07900	HSP90AA1	P33981	TTK	T115	G108D	108	Missense	distal	-7	no	23.955	23.522	PhosphoSitePlus	CCLE	18.469	Down-regulation
Other_TTK_TTK_ST	P07900	HSP90AA1	P33981	TTK	T305	Y309C	309	Missense	distal	4	no	20.048	20.365	EPSD	CCLE	18.469	Up-regulation
Other_TTK_TTK_ST	P07900	HSP90AA1	P33981	TTK	S476	D479N	479	Missense	distal	3	no	19.384	19.593	EPSD	CCLE	18.469	Up-regulation
Other_TTK_TTK_ST	P07900	HSP90AA1	P33981	TTK	T540	T540I	540	Missense	central	0	yes	21.749	0.000	EPSD	CCLE	18.469	Loss
Other_TTK_TTK_ST	P07900	HSP90AA1	P33981	TTK	S595	L592S	592	Missense	distal	-3	no	19.471	19.782	EPSD	CCLE	18.469	Up-regulation
Other_TTK_TTK_ST	P07900	HSP90AA1	P33981	TTK	T624	K631N	631	Missense	distal	7	no	21.880	21.599	EPSD	CCLE	18.469	Down-regulation
Other_TTK_TTK_ST	P07900	HSP90AA1	P33981	TTK	T624	M628K	628	Missense	distal	4	no	21.880	21.224	EPSD	CCLE	18.469	Down-regulation
Other_TTK_TTK_ST	P07900	HSP90AA1	P33981	TTK	T624	A618T	618	Missense	distal	-6	no	21.880	21.848	EPSD	CCLE	18.469	Down-regulation
Other_TTK_TTK_ST	Q53HL2	CDCA8	P33981	TTK	T169	A167V	167	Missense	proximal	-2	no	26.238	25.797	EPSD;PhosphoSitePlus	CCLE	18.469	Down-regulation
Other_TTK_TTK_ST	Q53HL2	CDCA8	P33981	TTK	T169	P172L	172	Missense	distal	3	no	26.238	31.449	EPSD;PhosphoSitePlus	CCLE	18.469	Up-regulation
Other_TTK_TTK_ST	Q53HL2	CDCA8	P33981	TTK	T199	R203C	203	Missense	distal	4	no	18.699	18.814	EPSD	CCLE	18.469	Up-regulation
Other_TTK_TTK_ST	P54132	BLM	P33981	TTK	S42	N46S	46	Missense	distal	4	no	19.623	20.192	EPSD	CCLE	18.469	Up-regulation
Other_TTK_TTK_ST	P54132	BLM	P33981	TTK	S43	N46S	46	Missense	distal	3	no	19.360	20.300	EPSD	CCLE	18.469	Up-regulation
Other_TTK_TTK_ST	P54132	BLM	P33981	TTK	S316	I309F	309	Missense	distal	-7	no	19.672	18.086	EPSD	CCLE	18.469	Loss
Other_TTK_TTK_ST	P54132	BLM	P33981	TTK	S328	D329H	329	Missense	proximal	1	no	20.257	20.237	EPSD	CCLE	18.469	Down-regulation
Other_TTK_TTK_ST	P54132	BLM	P33981	TTK	T742	A746V	746	Missense	distal	4	no	18.976	18.850	EPSD	CCLE	18.469	Down-regulation
Other_TTK_TTK_ST	P00519	ABL1	P33981	TTK	T83	K87E	87	Missense	distal	4	no	19.018	19.930	EPSD	CCLE	18.469	Up-regulation
Other_TTK_TTK_ST	P00519	ABL1	P33981	TTK	T117	P112S	112	Missense	distal	-5	no	20.666	21.382	EPSD	CCLE	18.469	Up-regulation
Other_TTK_TTK_ST	P00519	ABL1	P33981	TTK	T532	K531N	531	Missense	proximal	-1	no	18.272	19.395	EPSD	CCLE	18.469	Gain
Other_TTK_TTK_ST	P00519	ABL1	P33981	TTK	T597	N598S	598	Missense	proximal	1	no	20.253	20.254	EPSD	CCLE	18.469	Up-regulation
Other_TTK_TTK_ST	P00519	ABL1	P33981	TTK	S919	P914L	914	Missense	distal	-5	no	18.968	20.492	EPSD	CCLE	18.469	Up-regulation
Other_TTK_TTK_ST	Q9Y6D9	MAD1L1	P33981	TTK	S185	Q188H	188	Missense	distal	3	no	19.003	22.237	EPSD	CCLE	18.469	Up-regulation
Other_TTK_TTK_ST	Q96PE2	ARHGEF17	P33981	TTK	T751	S757I	757	Missense	distal	6	no	22.091	21.028	EPSD;PhosphoSitePlus	CCLE	18.469	Down-regulation
Other_TTK_TTK_ST	Q96PE2	ARHGEF17	P33981	TTK	T1077	A1071T	1071	Missense	distal	-6	no	19.824	19.792	EPSD	CCLE	18.469	Down-regulation
Other_TTK_TTK_ST	Q9Y6R1	SLC4A4	P33981	TTK	S77	N72H	72	Missense	distal	-5	no	19.968	17.983	EPSD	CCLE	18.469	Loss
Other_TTK_TTK_ST	Q9Y6R1	SLC4A4	P33981	TTK	S233	T239S	239	Missense	distal	6	no	19.105	17.610	EPSD	CCLE	18.469	Loss
Other_TTK_TTK_ST	O96017	CHEK2	P33981	TTK	S435	S435L	435	Missense	central	0	yes	19.782	0.000	EPSD	CCLE	18.469	Loss
Other_TTK_TTK_ST	O96017	CHEK2	P33981	TTK	S442	S435L	435	Missense	distal	-7	no	21.013	19.611	EPSD	CCLE	18.469	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	P35367	HRH1	P17252	PRKCA	T140	T140A	140	Missense	central	0	yes	16.754	0.000	EPSD	CCLE	16.704	Loss
AGC_PKC_PKCa_PRKCA_ST	P35367	HRH1	P17252	PRKCA	T142	T140A	140	Missense	proximal	-2	no	17.119	16.927	EPSD	CCLE	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	Q9BR39	JPH2	P17252	PRKCA	S235	V239A	239	Missense	distal	4	no	18.470	19.808	EPSD	CCLE	16.704	Up-regulation
AGC_PKC_PKCa_PRKCA_ST	Q9BR39	JPH2	P17252	PRKCA	S238	V239A	239	Missense	proximal	1	no	17.579	17.426	EPSD	CCLE	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	Q9BR39	JPH2	P17252	PRKCA	S241	V239A	239	Missense	proximal	-2	no	20.964	20.720	EPSD	CCLE	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	Q9BR39	JPH2	P17252	PRKCA	S244	V239A	239	Missense	distal	-5	no	17.352	17.436	EPSD	CCLE	16.704	Up-regulation
AGC_PKC_PKCa_PRKCA_ST	Q9BR39	JPH2	P17252	PRKCA	S359	K358T	358	Missense	proximal	-1	no	19.136	18.313	EPSD	CCLE	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	Q9BR39	JPH2	P17252	PRKCA	T477	E481D	481	Missense	distal	4	no	18.033	17.803	EPSD	CCLE	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	Q9BR39	JPH2	P17252	PRKCA	T477	E476Q	476	Missense	proximal	-1	no	18.033	17.585	EPSD	CCLE	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	Q9BR39	JPH2	P17252	PRKCA	T477	R475C	475	Missense	proximal	-2	no	18.033	16.334	EPSD	CCLE	16.704	Loss
AGC_PKC_PKCa_PRKCA_ST	Q9BR39	JPH2	P17252	PRKCA	S534	R533C	533	Missense	proximal	-1	no	19.046	16.386	EPSD	CCLE	16.704	Loss
AGC_PKC_PKCa_PRKCA_ST	Q9BR39	JPH2	P17252	PRKCA	S534	A530V	530	Missense	distal	-4	no	19.046	18.487	EPSD	CCLE	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	Q9BR39	JPH2	P17252	PRKCA	T540	R533C	533	Missense	distal	-7	no	18.930	18.911	EPSD	CCLE	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	P29966	MARCKS	P17252	PRKCA	S135	P136L	136	Missense	proximal	1	no	16.463	16.889	EPSD	CCLE	16.704	Gain
AGC_PKC_PKCa_PRKCA_ST	P29966	MARCKS	P17252	PRKCA	T150	S145A	145	Missense	distal	-5	no	18.612	18.559	EPSD	CCLE	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	Q92879	CELF1	P17252	PRKCA	S52	S58C	58	Missense	distal	6	no	17.180	17.012	EPSD;PhosphoSitePlus	CCLE	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	Q92879	CELF1	P17252	PRKCA	S52	V47I	47	Missense	distal	-5	no	17.180	17.173	EPSD;PhosphoSitePlus	CCLE	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	P11387	TOP1	P17252	PRKCA	S57	E63D	63	Missense	distal	6	no	18.319	18.336	EPSD	CCLE	16.704	Up-regulation
AGC_PKC_PKCa_PRKCA_ST	P11387	TOP1	P17252	PRKCA	S534	N539K	539	Missense	distal	5	no	20.451	20.957	EPSD	CCLE	16.704	Up-regulation
AGC_PKC_PKCa_PRKCA_ST	Q96PH1	NOX5	P17252	PRKCA	T32	Q33R	33	Missense	proximal	1	no	16.877	16.994	EPSD	CCLE	16.704	Up-regulation
AGC_PKC_PKCa_PRKCA_ST	Q96PH1	NOX5	P17252	PRKCA	S548	L554I	554	Missense	distal	6	no	18.034	18.011	EPSD	CCLE	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	O76090	BEST1	P17252	PRKCA	S16	R19W	19	Missense	distal	3	no	19.974	17.040	EPSD	CCLE	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	O76090	BEST1	P17252	PRKCA	T536	E538A	538	Missense	proximal	2	no	15.900	16.902	EPSD	CCLE	16.704	Gain
AGC_PKC_PKCa_PRKCA_ST	Q15080	NCF4	P17252	PRKCA	T154	R155Q	155	Missense	proximal	1	no	20.732	20.615	EPSD;PhosphoSitePlus	CCLE	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	Q15080	NCF4	P17252	PRKCA	S159	R155Q	155	Missense	distal	-4	no	16.862	16.485	EPSD	CCLE	16.704	Loss
AGC_PKC_PKCa_PRKCA_ST	P16144	ITGB4	P17252	PRKCA	S99	G105D	105	Missense	distal	6	no	18.291	18.351	EPSD	CCLE	16.704	Up-regulation
AGC_PKC_PKCa_PRKCA_ST	P16144	ITGB4	P17252	PRKCA	S102	G105D	105	Missense	distal	3	no	18.480	17.395	EPSD	CCLE	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	P16144	ITGB4	P17252	PRKCA	S102	R107Q	107	Missense	distal	5	no	18.480	18.472	EPSD	CCLE	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	P16144	ITGB4	P17252	PRKCA	S397	F390S	390	Missense	distal	-7	no	17.492	17.500	EPSD	CCLE	16.704	Up-regulation
AGC_PKC_PKCa_PRKCA_ST	P16144	ITGB4	P17252	PRKCA	S397	E404G	404	Missense	distal	7	no	17.492	17.563	EPSD	CCLE	16.704	Up-regulation
AGC_PKC_PKCa_PRKCA_ST	Q8NER1	TRPV1	P17252	PRKCA	S117	V122I	122	Missense	distal	5	no	18.829	18.916	EPSD	CCLE	16.704	Up-regulation
AGC_PKC_PKCa_PRKCA_ST	P19174	PLCG1	P17252	PRKCA	S1248	Y1253F	1253	Missense	distal	5	no	19.739	19.746	PhosphoSitePlus	CCLE	16.704	Up-regulation
AGC_PKC_PKCa_PRKCA_ST	P10636	MAPT	P17252	PRKCA	S171	P170F	170	Missense	proximal	-1	no	19.508	19.100	EPSD	CCLE	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	P10636	MAPT	P17252	PRKCA	S171	G174A	174	Missense	distal	3	no	19.508	18.550	EPSD	CCLE	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	P10636	MAPT	P17252	PRKCA	S400	K405R	405	Missense	distal	5	no	20.635	20.491	EPSD	CCLE	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	P10636	MAPT	P17252	PRKCA	T403	K405R	405	Missense	proximal	2	no	17.027	17.449	EPSD	CCLE	16.704	Up-regulation
AGC_PKC_PKCa_PRKCA_ST	P10636	MAPT	P17252	PRKCA	S411	K405R	405	Missense	distal	-6	no	18.586	18.593	EPSD	CCLE	16.704	Up-regulation
AGC_PKC_PKCa_PRKCA_ST	P10636	MAPT	P17252	PRKCA	S447	V442I	442	Missense	distal	-5	no	17.139	17.131	EPSD	CCLE	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	P10636	MAPT	P17252	PRKCA	S531	R526L	526	Missense	distal	-5	no	18.059	17.932	EPSD	CCLE	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	P10636	MAPT	P17252	PRKCA	S555	R559H	559	Missense	distal	4	no	19.645	19.363	EPSD	CCLE	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	P10636	MAPT	P17252	PRKCA	S637	D631E	631	Missense	distal	-6	no	18.000	18.083	EPSD	CCLE	16.704	Up-regulation
AGC_PKC_PKCa_PRKCA_ST	P10636	MAPT	P17252	PRKCA	S721	S717C	717	Missense	distal	-4	no	18.782	17.632	EPSD	CCLE	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	P10636	MAPT	P17252	PRKCA	S721	S721C	721	Missense	central	0	yes	18.782	0.000	EPSD	CCLE	16.704	Loss
AGC_PKC_PKCa_PRKCA_ST	P10636	MAPT	P17252	PRKCA	S721	H724R	724	Missense	distal	3	no	18.782	19.494	EPSD	CCLE	16.704	Up-regulation
AGC_PKC_PKCa_PRKCA_ST	P10636	MAPT	P17252	PRKCA	S726	H724R	724	Missense	proximal	-2	no	14.096	18.650	EPSD	CCLE	16.704	Gain
AGC_PKC_PKCa_PRKCA_ST	P05107	ITGB2	P17252	PRKCA	T118	V117M	117	Missense	proximal	-1	no	19.005	21.127	EPSD	CCLE	16.704	Up-regulation
AGC_PKC_PKCa_PRKCA_ST	P19086	GNAZ	P17252	PRKCA	S16	R14W	14	Missense	proximal	-2	no	23.083	21.085	PhosphoSitePlus;EPSD	CCLE	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	P19086	GNAZ	P17252	PRKCA	S16	S16P	16	Missense	central	0	yes	23.083	0.000	PhosphoSitePlus;EPSD	CCLE	16.704	Loss
AGC_PKC_PKCa_PRKCA_ST	O60941	DTNB	P17252	PRKCA	S250	R257Q	257	Missense	distal	7	no	21.054	21.050	EPSD	CCLE	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	Q9UKG1	APPL1	P17252	PRKCA	T422	R419Q	419	Missense	distal	-3	no	18.435	15.578	EPSD	CCLE	16.704	Loss
AGC_PKC_PKCa_PRKCA_ST	Q9UKG1	APPL1	P17252	PRKCA	S597	Y604C	604	Missense	distal	7	no	17.031	16.860	EPSD	CCLE	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	O14493	CLDN4	P17252	PRKCA	S194	A200G	200	Missense	distal	6	no	17.231	17.124	PhosphoSitePlus	CCLE	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	Q9H3Q1	CDC42EP4	P17252	PRKCA	S9	P2S	2	Missense	distal	-7	no	17.716	17.719	EPSD	CCLE	16.704	Up-regulation
AGC_PKC_PKCa_PRKCA_ST	Q9H3Q1	CDC42EP4	P17252	PRKCA	S73	S70C	70	Missense	distal	-3	no	20.992	21.123	EPSD	CCLE	16.704	Up-regulation
AGC_PKC_PKCa_PRKCA_ST	Q9H3Q1	CDC42EP4	P17252	PRKCA	S74	S70C	70	Missense	distal	-4	no	19.377	18.226	EPSD	CCLE	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	Q9H3Q1	CDC42EP4	P17252	PRKCA	S77	S70C	70	Missense	distal	-7	no	18.331	18.318	EPSD	CCLE	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	Q9H3Q1	CDC42EP4	P17252	PRKCA	S105	R100H	100	Missense	distal	-5	no	19.370	19.014	EPSD	CCLE	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	Q9H3Q1	CDC42EP4	P17252	PRKCA	S295	A288S	288	Missense	distal	-7	no	18.309	18.307	EPSD	CCLE	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	Q07954	LRP1	P17252	PRKCA	S508	D515Y	515	Missense	distal	7	no	18.650	18.641	EPSD	CCLE	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	Q07954	LRP1	P17252	PRKCA	S514	D515Y	515	Missense	proximal	1	no	17.600	18.836	EPSD	CCLE	16.704	Up-regulation
AGC_PKC_PKCa_PRKCA_ST	Q07954	LRP1	P17252	PRKCA	S2950	C2956Y	2956	Missense	distal	6	no	16.788	16.974	EPSD	CCLE	16.704	Up-regulation
AGC_PKC_PKCa_PRKCA_ST	Q07954	LRP1	P17252	PRKCA	T4034	A4030V	4030	Missense	distal	-4	no	17.363	16.804	EPSD	CCLE	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	Q07954	LRP1	P17252	PRKCA	S4071	G4070S	4070	Missense	proximal	-1	no	18.278	18.030	EPSD	CCLE	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	Q07954	LRP1	P17252	PRKCA	S4071	R4073Q	4073	Missense	proximal	2	no	18.278	14.444	EPSD	CCLE	16.704	Loss
AGC_PKC_PKCa_PRKCA_ST	P52565	ARHGDIA	P17252	PRKCA	S96	S96N	96	Missense	central	0	yes	20.335	0.000	EPSD;PhosphoSitePlus	CCLE	16.704	Loss
AGC_PKC_PKCa_PRKCA_ST	P52565	ARHGDIA	P17252	PRKCA	S96	L94P	94	Missense	proximal	-2	no	20.335	19.981	EPSD;PhosphoSitePlus	CCLE	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	P52565	ARHGDIA	P17252	PRKCA	S96	D93N	93	Missense	distal	-3	no	20.335	21.151	EPSD;PhosphoSitePlus	CCLE	16.704	Up-regulation
AGC_PKC_PKCa_PRKCA_ST	P52565	ARHGDIA	P17252	PRKCA	S176	Y175C	175	Missense	proximal	-1	no	17.490	15.667	EPSD	CCLE	16.704	Loss
AGC_PKC_PKCa_PRKCA_ST	P53004	BLVRA	P17252	PRKCA	S21	R18Q	18	Missense	distal	-3	no	24.825	21.968	EPSD	CCLE	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	P08183	ABCB1	P17252	PRKCA	S683	K685N	685	Missense	proximal	2	no	22.617	17.668	EPSD	CCLE	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	P78536	ADAM17	P17252	PRKCA	S608	R610H	610	Missense	proximal	2	no	18.266	13.242	EPSD	CCLE	16.704	Loss
AGC_PKC_PKCa_PRKCA_ST	P78536	ADAM17	P17252	PRKCA	T761	D760A	760	Missense	proximal	-1	no	17.286	17.223	EPSD	CCLE	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	O95243	MBD4	P17252	PRKCA	S122	H129Q	129	Missense	distal	7	no	17.120	17.187	EPSD	CCLE	16.704	Up-regulation
AGC_PKC_PKCa_PRKCA_ST	P48048	KCNJ1	P17252	PRKCA	S4	S5I	5	Missense	proximal	1	no	17.686	19.348	EPSD;PhosphoSitePlus	CCLE	16.704	Up-regulation
AGC_PKC_PKCa_PRKCA_ST	P55042	RRAD	P17252	PRKCA	S26	P28T	28	Missense	proximal	2	no	19.696	20.088	EPSD	CCLE	16.704	Up-regulation
AGC_PKC_PKCa_PRKCA_ST	P55042	RRAD	P17252	PRKCA	T27	P28T	28	Missense	proximal	1	no	17.331	17.258	EPSD	CCLE	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	P55042	RRAD	P17252	PRKCA	S214	E212K	212	Missense	proximal	-2	no	15.893	18.392	EPSD;PhosphoSitePlus	CCLE	16.704	Gain
AGC_PKC_PKCa_PRKCA_ST	P11831	SRF	P17252	PRKCA	S16	S21N	21	Missense	distal	5	no	21.197	20.976	EPSD	CCLE	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	P11831	SRF	P17252	PRKCA	T27	S21N	21	Missense	distal	-6	no	20.478	20.421	EPSD	CCLE	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	P11831	SRF	P17252	PRKCA	S237	R235I	235	Missense	proximal	-2	no	18.458	14.870	EPSD	CCLE	16.704	Loss
AGC_PKC_PKCa_PRKCA_ST	P04004	VTN	P17252	PRKCA	S225	F222L	222	Missense	distal	-3	no	17.604	15.869	EPSD	CCLE	16.704	Loss
AGC_PKC_PKCa_PRKCA_ST	P60983	GMFB	P17252	PRKCA	T27	I32L	32	Missense	distal	5	no	16.999	17.002	EPSD	CCLE	16.704	Up-regulation
AGC_PKC_PKCa_PRKCA_ST	Q8NF50	DOCK8	P17252	PRKCA	S936	D929E	929	Missense	distal	-7	no	17.978	17.975	EPSD	CCLE	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	Q8NF50	DOCK8	P17252	PRKCA	S936	M935I	935	Missense	proximal	-1	no	17.978	16.036	EPSD	CCLE	16.704	Loss
AGC_PKC_PKCa_PRKCA_ST	Q8NF50	DOCK8	P17252	PRKCA	S1091	E1095K	1095	Missense	distal	4	no	16.425	16.964	EPSD	CCLE	16.704	Gain
AGC_PKC_PKCa_PRKCA_ST	Q8NF50	DOCK8	P17252	PRKCA	S2087	E2092G	2092	Missense	distal	5	no	19.066	19.055	PhosphoSitePlus;EPSD	CCLE	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	Q12809	KCNH2	P17252	PRKCA	S283	E289K	289	Missense	distal	6	no	18.835	18.929	EPSD	CCLE	16.704	Up-regulation
AGC_PKC_PKCa_PRKCA_ST	Q12809	KCNH2	P17252	PRKCA	S284	E289K	289	Missense	distal	5	no	17.217	17.631	EPSD	CCLE	16.704	Up-regulation
AGC_PKC_PKCa_PRKCA_ST	Q12809	KCNH2	P17252	PRKCA	S354	E357V	357	Missense	distal	3	no	17.261	16.645	EPSD	CCLE	16.704	Loss
AGC_PKC_PKCa_PRKCA_ST	Q12809	KCNH2	P17252	PRKCA	S882	R887H	887	Missense	distal	5	no	17.861	17.601	EPSD	CCLE	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	Q12809	KCNH2	P17252	PRKCA	S890	R887H	887	Missense	distal	-3	no	27.532	23.675	PhosphoSitePlus	CCLE	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	Q12809	KCNH2	P17252	PRKCA	S960	S959F	959	Missense	proximal	-1	no	18.190	17.482	EPSD	CCLE	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	Q9NRY4	ARHGAP35	P17252	PRKCA	S46	R41C	41	Missense	distal	-5	no	17.404	16.728	EPSD	CCLE	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	Q9NRY4	ARHGAP35	P17252	PRKCA	S46	A47V	47	Missense	proximal	1	no	17.404	17.557	EPSD	CCLE	16.704	Up-regulation
AGC_PKC_PKCa_PRKCA_ST	Q9NRY4	ARHGAP35	P17252	PRKCA	S860	F858C	858	Missense	proximal	-2	no	16.881	19.155	EPSD	CCLE	16.704	Up-regulation
AGC_PKC_PKCa_PRKCA_ST	Q9NRY4	ARHGAP35	P17252	PRKCA	S1236	S1236A	1236	Missense	central	0	yes	18.753	0.000	PhosphoSitePlus;EPSD	CCLE	16.704	Loss
AGC_PKC_PKCa_PRKCA_ST	P16150	SPN	P17252	PRKCA	S368	G371R	371	Missense	distal	3	no	20.566	21.205	EPSD	CCLE	16.704	Up-regulation
AGC_PKC_PKCa_PRKCA_ST	O60716	CTNND1	P17252	PRKCA	S15	E20K	20	Missense	distal	5	no	19.293	19.707	EPSD	CCLE	16.704	Up-regulation
AGC_PKC_PKCa_PRKCA_ST	O60716	CTNND1	P17252	PRKCA	S244	A250E	250	Missense	distal	6	no	17.200	17.136	EPSD	CCLE	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	O60716	CTNND1	P17252	PRKCA	S484	M487I	487	Missense	distal	3	no	20.140	18.859	EPSD	CCLE	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	O60716	CTNND1	P17252	PRKCA	S539	R546W	546	Missense	distal	7	no	19.007	18.827	EPSD	CCLE	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	Q9NQA5	TRPV5	P17252	PRKCA	S142	A141D	141	Missense	proximal	-1	no	19.851	19.915	EPSD	CCLE	16.704	Up-regulation
AGC_PKC_PKCa_PRKCA_ST	Q14315	FLNC	P17252	PRKCA	S78	Y83C	83	Missense	distal	5	no	19.836	19.218	EPSD	CCLE	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	Q14315	FLNC	P17252	PRKCA	T423	V424M	424	Missense	proximal	1	no	17.935	17.595	EPSD	CCLE	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	Q14315	FLNC	P17252	PRKCA	S480	R478S	478	Missense	proximal	-2	no	22.448	19.147	EPSD	CCLE	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	Q14315	FLNC	P17252	PRKCA	T1809	T1809M	1809	Missense	central	0	yes	17.429	0.000	EPSD	CCLE	16.704	Loss
AGC_PKC_PKCa_PRKCA_ST	Q14432	PDE3A	P17252	PRKCA	S62	C66F	66	Missense	distal	4	no	16.432	17.226	EPSD	CCLE	16.704	Gain
AGC_PKC_PKCa_PRKCA_ST	Q14432	PDE3A	P17252	PRKCA	S63	C66F	66	Missense	distal	3	no	16.273	16.988	EPSD	CCLE	16.704	Gain
AGC_PKC_PKCa_PRKCA_ST	Q14432	PDE3A	P17252	PRKCA	S593	S586N	586	Missense	distal	-7	no	17.099	17.095	EPSD	CCLE	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	Q8WZ42	TTN	P17252	PRKCA	S57	V54M	54	Missense	distal	-3	no	16.136	16.853	EPSD	CCLE	16.704	Gain
AGC_PKC_PKCa_PRKCA_ST	Q8WZ42	TTN	P17252	PRKCA	T330	T330A	330	Missense	central	0	yes	16.940	0.000	EPSD	CCLE	16.704	Loss
AGC_PKC_PKCa_PRKCA_ST	Q8WZ42	TTN	P17252	PRKCA	S1348	I1351V	1351	Missense	distal	3	no	20.626	21.321	EPSD	CCLE	16.704	Up-regulation
AGC_PKC_PKCa_PRKCA_ST	Q8WZ42	TTN	P17252	PRKCA	S1433	R1436K	1436	Missense	distal	3	no	17.000	16.377	EPSD	CCLE	16.704	Loss
AGC_PKC_PKCa_PRKCA_ST	Q8WZ42	TTN	P17252	PRKCA	S3118	A3124T	3124	Missense	distal	6	no	16.900	16.822	EPSD	CCLE	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	Q8WZ42	TTN	P17252	PRKCA	S4196	S4196P	4196	Missense	central	0	yes	18.347	0.000	EPSD	CCLE	16.704	Loss
AGC_PKC_PKCa_PRKCA_ST	Q8WZ42	TTN	P17252	PRKCA	S4527	A4529T	4529	Missense	proximal	2	no	17.126	17.014	EPSD	CCLE	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	Q8WZ42	TTN	P17252	PRKCA	S4993	N4996Y	4996	Missense	distal	3	no	21.337	20.639	EPSD	CCLE	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	Q8WZ42	TTN	P17252	PRKCA	S5276	S5280F	5280	Missense	distal	4	no	20.337	19.975	EPSD	CCLE	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	Q8WZ42	TTN	P17252	PRKCA	S7471	D7466A	7466	Missense	distal	-5	no	17.534	17.440	EPSD	CCLE	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	Q8WZ42	TTN	P17252	PRKCA	S7471	T7467S	7467	Missense	distal	-4	no	17.534	18.196	EPSD	CCLE	16.704	Up-regulation
AGC_PKC_PKCa_PRKCA_ST	Q8WZ42	TTN	P17252	PRKCA	S7628	V7626A	7626	Missense	proximal	-2	no	17.767	17.523	EPSD	CCLE	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	Q8WZ42	TTN	P17252	PRKCA	S9803	Q9804K	9804	Missense	proximal	1	no	16.678	16.832	EPSD	CCLE	16.704	Gain
AGC_PKC_PKCa_PRKCA_ST	Q8WZ42	TTN	P17252	PRKCA	T9970	M9967L	9967	Missense	distal	-3	no	17.131	15.747	EPSD	CCLE	16.704	Loss
AGC_PKC_PKCa_PRKCA_ST	Q8WZ42	TTN	P17252	PRKCA	S10781	K10777N	10777	Missense	distal	-4	no	17.301	16.743	EPSD	CCLE	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	Q8WZ42	TTN	P17252	PRKCA	S12911	G12907V	12907	Missense	distal	-4	no	18.194	17.631	EPSD	CCLE	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	Q8WZ42	TTN	P17252	PRKCA	S13707	R13705H	13705	Missense	proximal	-2	no	19.302	14.748	EPSD	CCLE	16.704	Loss
AGC_PKC_PKCa_PRKCA_ST	Q8WZ42	TTN	P17252	PRKCA	S13802	H13804R	13804	Missense	proximal	2	no	15.592	20.616	EPSD	CCLE	16.704	Gain
AGC_PKC_PKCa_PRKCA_ST	Q8WZ42	TTN	P17252	PRKCA	S13980	T13979I	13979	Missense	proximal	-1	no	17.668	16.763	EPSD	CCLE	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	Q8WZ42	TTN	P17252	PRKCA	T14402	G14405E	14405	Missense	distal	3	no	17.086	16.487	EPSD	CCLE	16.704	Loss
AGC_PKC_PKCa_PRKCA_ST	Q8WZ42	TTN	P17252	PRKCA	T14868	L14874V	14874	Missense	distal	6	no	16.744	16.665	EPSD	CCLE	16.704	Loss
AGC_PKC_PKCa_PRKCA_ST	Q8WZ42	TTN	P17252	PRKCA	T14875	L14874V	14874	Missense	proximal	-1	no	19.545	18.502	EPSD	CCLE	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	Q8WZ42	TTN	P17252	PRKCA	S15744	W15749C	15749	Missense	distal	5	no	16.939	16.715	EPSD	CCLE	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	Q8WZ42	TTN	P17252	PRKCA	S16329	T16334A	16334	Missense	distal	5	no	20.986	21.264	EPSD	CCLE	16.704	Up-regulation
AGC_PKC_PKCa_PRKCA_ST	Q8WZ42	TTN	P17252	PRKCA	T16334	T16334A	16334	Missense	central	0	yes	18.620	0.000	EPSD	CCLE	16.704	Loss
AGC_PKC_PKCa_PRKCA_ST	Q8WZ42	TTN	P17252	PRKCA	S16412	T16405I	16405	Missense	distal	-7	no	18.070	18.064	EPSD	CCLE	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	Q8WZ42	TTN	P17252	PRKCA	T16931	P16938S	16938	Missense	distal	7	no	22.219	22.183	EPSD	CCLE	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	Q8WZ42	TTN	P17252	PRKCA	S18976	W18975G	18975	Missense	proximal	-1	no	15.430	16.876	EPSD	CCLE	16.704	Gain
AGC_PKC_PKCa_PRKCA_ST	Q8WZ42	TTN	P17252	PRKCA	S19174	D19180Y	19180	Missense	distal	6	no	17.207	17.244	EPSD	CCLE	16.704	Up-regulation
AGC_PKC_PKCa_PRKCA_ST	Q8WZ42	TTN	P17252	PRKCA	T20168	Q20172L	20172	Missense	distal	4	no	17.399	16.578	EPSD	CCLE	16.704	Loss
AGC_PKC_PKCa_PRKCA_ST	Q8WZ42	TTN	P17252	PRKCA	S20255	S20255Y	20255	Missense	central	0	yes	18.384	0.000	EPSD	CCLE	16.704	Loss
AGC_PKC_PKCa_PRKCA_ST	Q8WZ42	TTN	P17252	PRKCA	S20864	M20860I	20860	Missense	distal	-4	no	17.175	16.461	EPSD	CCLE	16.704	Loss
AGC_PKC_PKCa_PRKCA_ST	Q8WZ42	TTN	P17252	PRKCA	S21518	A21515S	21515	Missense	distal	-3	no	16.078	17.656	EPSD	CCLE	16.704	Gain
AGC_PKC_PKCa_PRKCA_ST	Q8WZ42	TTN	P17252	PRKCA	S22272	M22278T	22278	Missense	distal	6	no	17.084	17.037	EPSD	CCLE	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	Q8WZ42	TTN	P17252	PRKCA	S24704	S24698L	24698	Missense	distal	-6	no	18.327	18.262	EPSD	CCLE	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	Q8WZ42	TTN	P17252	PRKCA	S25442	G25436E	25436	Missense	distal	-6	no	16.953	16.986	EPSD	CCLE	16.704	Up-regulation
AGC_PKC_PKCa_PRKCA_ST	Q8WZ42	TTN	P17252	PRKCA	S25442	P25435L	25435	Missense	distal	-7	no	16.953	16.950	EPSD	CCLE	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	Q8WZ42	TTN	P17252	PRKCA	S26472	R26470I	26470	Missense	proximal	-2	no	16.863	13.275	EPSD	CCLE	16.704	Loss
AGC_PKC_PKCa_PRKCA_ST	Q8WZ42	TTN	P17252	PRKCA	S26627	W26632L	26632	Missense	distal	5	no	17.672	17.847	EPSD	CCLE	16.704	Up-regulation
AGC_PKC_PKCa_PRKCA_ST	Q8WZ42	TTN	P17252	PRKCA	S26629	H26636R	26636	Missense	distal	7	no	18.523	18.594	EPSD	CCLE	16.704	Up-regulation
AGC_PKC_PKCa_PRKCA_ST	Q8WZ42	TTN	P17252	PRKCA	S26629	W26632L	26632	Missense	distal	3	no	18.523	19.219	EPSD	CCLE	16.704	Up-regulation
AGC_PKC_PKCa_PRKCA_ST	Q8WZ42	TTN	P17252	PRKCA	T27299	I27298R	27298	Missense	proximal	-1	no	16.665	18.336	EPSD	CCLE	16.704	Gain
AGC_PKC_PKCa_PRKCA_ST	Q8WZ42	TTN	P17252	PRKCA	S28340	S28347F	28347	Missense	distal	7	no	18.217	18.153	EPSD	CCLE	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	Q8WZ42	TTN	P17252	PRKCA	S28343	S28350F	28350	Missense	distal	7	no	17.042	16.979	EPSD	CCLE	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	Q8WZ42	TTN	P17252	PRKCA	S28343	S28347F	28347	Missense	distal	4	no	17.042	16.681	EPSD	CCLE	16.704	Loss
AGC_PKC_PKCa_PRKCA_ST	Q8WZ42	TTN	P17252	PRKCA	S28540	F28536L	28536	Missense	distal	-4	no	16.943	16.570	EPSD	CCLE	16.704	Loss
AGC_PKC_PKCa_PRKCA_ST	Q8WZ42	TTN	P17252	PRKCA	S28637	S28636L	28636	Missense	proximal	-1	no	17.529	17.110	EPSD	CCLE	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	Q8WZ42	TTN	P17252	PRKCA	S28966	A28960T	28960	Missense	distal	-6	no	18.220	18.131	EPSD	CCLE	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	Q8WZ42	TTN	P17252	PRKCA	S30855	V30849I	30849	Missense	distal	-6	no	21.185	21.201	EPSD	CCLE	16.704	Up-regulation
AGC_PKC_PKCa_PRKCA_ST	Q8WZ42	TTN	P17252	PRKCA	S31105	R31107L	31107	Missense	proximal	2	no	19.021	14.034	EPSD	CCLE	16.704	Loss
AGC_PKC_PKCa_PRKCA_ST	Q8WZ42	TTN	P17252	PRKCA	S31449	K31453N	31453	Missense	distal	4	no	20.611	19.484	EPSD	CCLE	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	Q8WZ42	TTN	P17252	PRKCA	T32877	A32872S	32872	Missense	distal	-5	no	17.132	17.185	EPSD	CCLE	16.704	Up-regulation
AGC_PKC_PKCa_PRKCA_ST	Q8WZ42	TTN	P17252	PRKCA	T32998	D33004N	33004	Missense	distal	6	no	18.039	17.955	EPSD	CCLE	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	Q8WZ42	TTN	P17252	PRKCA	S33013	S33018Y	33018	Missense	distal	5	no	20.242	20.269	EPSD	CCLE	16.704	Up-regulation
AGC_PKC_PKCa_PRKCA_ST	Q8WZ42	TTN	P17252	PRKCA	S33013	D33016V	33016	Missense	distal	3	no	20.242	20.113	EPSD	CCLE	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	Q8WZ42	TTN	P17252	PRKCA	S33066	S33065Y	33065	Missense	proximal	-1	no	17.363	16.914	EPSD	CCLE	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	Q8WZ42	TTN	P17252	PRKCA	T33279	A33276D	33276	Missense	distal	-3	no	16.903	16.310	EPSD	CCLE	16.704	Loss
AGC_PKC_PKCa_PRKCA_ST	Q8WZ42	TTN	P17252	PRKCA	S33400	R33403K	33403	Missense	distal	3	no	17.797	17.175	EPSD	CCLE	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	Q8WZ42	TTN	P17252	PRKCA	T33498	E33501K	33501	Missense	distal	3	no	17.246	17.862	EPSD	CCLE	16.704	Up-regulation
AGC_PKC_PKCa_PRKCA_ST	Q8WZ42	TTN	P17252	PRKCA	T33498	T33498I	33498	Missense	central	0	yes	17.246	0.000	EPSD	CCLE	16.704	Loss
AGC_PKC_PKCa_PRKCA_ST	Q8WZ42	TTN	P17252	PRKCA	T33498	M33497A	33497	Missense	proximal	-1	no	17.246	16.027	EPSD	CCLE	16.704	Loss
AGC_PKC_PKCa_PRKCA_ST	Q8WZ42	TTN	P17252	PRKCA	S33504	E33501K	33501	Missense	distal	-3	no	14.543	17.456	EPSD	CCLE	16.704	Gain
AGC_PKC_PKCa_PRKCA_ST	P49841	GSK3B	P17252	PRKCA	S147	T152M	152	Missense	distal	5	no	17.546	17.848	EPSD	CCLE	16.704	Up-regulation
AGC_PKC_PKCa_PRKCA_ST	P35579	MYH9	P17252	PRKCA	S232	N229K	229	Missense	distal	-3	no	16.213	18.414	EPSD	CCLE	16.704	Gain
AGC_PKC_PKCa_PRKCA_ST	P35579	MYH9	P17252	PRKCA	S232	N229S	229	Missense	distal	-3	no	16.213	17.570	EPSD	CCLE	16.704	Gain
AGC_PKC_PKCa_PRKCA_ST	P35579	MYH9	P17252	PRKCA	T638	T645A	645	Missense	distal	7	no	16.837	16.828	EPSD	CCLE	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	P35579	MYH9	P17252	PRKCA	S1869	T1870A	1870	Missense	proximal	1	no	17.616	18.087	EPSD	CCLE	16.704	Up-regulation
AGC_PKC_PKCa_PRKCA_ST	P17812	CTPS1	P17252	PRKCA	S200	P196T	196	Missense	distal	-4	no	19.253	18.763	EPSD	CCLE	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	Q16658	FSCN1	P17252	PRKCA	S39	L40P	40	Missense	proximal	1	no	20.677	20.250	PhosphoSitePlus	CCLE	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	Q16658	FSCN1	P17252	PRKCA	S187	V188M	188	Missense	proximal	1	no	17.746	17.407	EPSD	CCLE	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	Q15717	ELAVL1	P17252	PRKCA	S202	A204V	204	Missense	proximal	2	no	17.216	16.901	EPSD	CCLE	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	Q15717	ELAVL1	P17252	PRKCA	S221	G224D	224	Missense	distal	3	no	18.232	17.146	PhosphoSitePlus;EPSD	CCLE	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	P07355	ANXA2	P17252	PRKCA	S236	S234R	234	Missense	proximal	-2	no	15.388	18.690	EPSD	CCLE	16.704	Gain
AGC_PKC_PKCa_PRKCA_ST	P07355	ANXA2	P17252	PRKCA	S243	M240V	240	Missense	distal	-3	no	19.055	18.337	EPSD	CCLE	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	P21359	NF1	P17252	PRKCA	S2810	T2805I	2805	Missense	distal	-5	no	20.229	19.757	EPSD	CCLE	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	Q05193	DNM1	P17252	PRKCA	S795	V788E	788	Missense	distal	-7	no	18.100	18.101	EPSD	CCLE	16.704	Up-regulation
AGC_PKC_PKCa_PRKCA_ST	P04049	RAF1	P17252	PRKCA	S43	A42I	42	Missense	proximal	-1	no	19.600	18.875	EPSD;PhosphoSitePlus	CCLE	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	P04049	RAF1	P17252	PRKCA	S352	S352L	352	Missense	central	0	yes	16.787	0.000	EPSD	CCLE	16.704	Loss
AGC_PKC_PKCa_PRKCA_ST	O94806	PRKD3	P17252	PRKCA	S406	V403D	403	Missense	distal	-3	no	21.892	20.540	EPSD	CCLE	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	O94806	PRKD3	P17252	PRKCA	S442	L445P	445	Missense	distal	3	no	16.000	16.707	EPSD	CCLE	16.704	Gain
AGC_PKC_PKCa_PRKCA_ST	P10275	AR	P17252	PRKCA	S29	V33L	33	Missense	distal	4	no	16.872	17.401	EPSD	CCLE	16.704	Up-regulation
AGC_PKC_PKCa_PRKCA_ST	P10275	AR	P17252	PRKCA	S29	V33A	33	Missense	distal	4	no	16.872	18.210	EPSD	CCLE	16.704	Up-regulation
AGC_PKC_PKCa_PRKCA_ST	P10275	AR	P17252	PRKCA	S29	N36S	36	Missense	distal	7	no	16.872	16.896	EPSD	CCLE	16.704	Up-regulation
AGC_PKC_PKCa_PRKCA_ST	P10415	BCL2	P17252	PRKCA	S24	L23R	23	Missense	proximal	-1	no	20.144	20.951	EPSD	CCLE	16.704	Up-regulation
AGC_PKC_PKCa_PRKCA_ST	P10415	BCL2	P17252	PRKCA	S70	Q73H	73	Missense	distal	3	no	15.347	17.088	PhosphoSitePlus	CCLE	16.704	Gain
AGC_PKC_PKCa_PRKCA_ST	P13569	CFTR	P17252	PRKCA	S4	Q2E	2	Missense	proximal	-2	no	17.326	14.959	EPSD	CCLE	16.704	Loss
AGC_PKC_PKCa_PRKCA_ST	P13569	CFTR	P17252	PRKCA	S4	R3S	3	Missense	proximal	-1	no	17.326	16.939	EPSD	CCLE	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	P13569	CFTR	P17252	PRKCA	S686	E692K	692	Missense	distal	6	no	19.152	19.246	EPSD	CCLE	16.704	Up-regulation
AGC_PKC_PKCa_PRKCA_ST	P13569	CFTR	P17252	PRKCA	S813	G817C	817	Missense	distal	4	no	18.100	17.303	EPSD;PhosphoSitePlus	CCLE	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	P13569	CFTR	P17252	PRKCA	S1248	T1246P	1246	Missense	proximal	-2	no	21.308	21.160	EPSD	CCLE	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	Q15172	PPP2R5A	P17252	PRKCA	S2	P6S	6	Missense	distal	4	no	17.465	17.665	EPSD	CCLE	16.704	Up-regulation
AGC_PKC_PKCa_PRKCA_ST	Q9Y624	F11R	P17252	PRKCA	S274	S274L	274	Missense	central	0	yes	18.112	0.000	EPSD	CCLE	16.704	Loss
AGC_PKC_PKCa_PRKCA_ST	P21399	ACO1	P17252	PRKCA	S778	G775D	775	Missense	distal	-3	no	17.767	15.987	EPSD	CCLE	16.704	Loss
AGC_PKC_PKCa_PRKCA_ST	P21731	TBXA2R	P17252	PRKCA	S128	L132P	132	Missense	distal	4	no	17.295	17.887	EPSD	CCLE	16.704	Up-regulation
AGC_PKC_PKCa_PRKCA_ST	P21731	TBXA2R	P17252	PRKCA	S324	R326L	326	Missense	proximal	2	no	18.282	13.295	EPSD;PhosphoSitePlus	CCLE	16.704	Loss
AGC_PKC_PKCa_PRKCA_ST	P21731	TBXA2R	P17252	PRKCA	S324	S324G	324	Missense	central	0	yes	18.282	0.000	EPSD;PhosphoSitePlus	CCLE	16.704	Loss
AGC_PKC_PKCa_PRKCA_ST	P06213	INSR	P17252	PRKCA	S98	L102P	102	Missense	distal	4	no	18.927	19.519	EPSD	CCLE	16.704	Up-regulation
AGC_PKC_PKCa_PRKCA_ST	P06213	INSR	P17252	PRKCA	S98	R92Q	92	Missense	distal	-6	no	18.927	18.784	EPSD	CCLE	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	Q05940	SLC18A2	P17252	PRKCA	S15	Q13E	13	Missense	proximal	-2	no	21.540	19.172	EPSD;PhosphoSitePlus	CCLE	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	Q05940	SLC18A2	P17252	PRKCA	S18	Q13E	13	Missense	distal	-5	no	20.856	20.701	PhosphoSitePlus;EPSD	CCLE	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	Q05940	SLC18A2	P17252	PRKCA	S279	V275A	275	Missense	distal	-4	no	21.202	21.761	EPSD	CCLE	16.704	Up-regulation
AGC_PKC_PKCa_PRKCA_ST	Q05940	SLC18A2	P17252	PRKCA	S279	P284H	284	Missense	distal	5	no	21.202	20.925	EPSD	CCLE	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	P35612	ADD2	P17252	PRKCA	S62	L67V	67	Missense	distal	5	no	18.890	18.800	EPSD	CCLE	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	P35612	ADD2	P17252	PRKCA	S686	G690A	690	Missense	distal	4	no	16.369	16.742	EPSD	CCLE	16.704	Gain
AGC_PKC_PKCa_PRKCA_ST	Q9NRF2	SH2B1	P17252	PRKCA	S25	P21L	21	Missense	distal	-4	no	18.491	18.231	EPSD	CCLE	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	Q9NRF2	SH2B1	P17252	PRKCA	S384	M388V	388	Missense	distal	4	no	17.651	16.279	EPSD	CCLE	16.704	Loss
AGC_PKC_PKCa_PRKCA_ST	O95786	DDX58	P17252	PRKCA	S468	K472E	472	Missense	distal	4	no	19.174	18.635	EPSD	CCLE	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	P07949	RET	P17252	PRKCA	S686	S688F	688	Missense	proximal	2	no	16.759	17.076	EPSD	CCLE	16.704	Up-regulation
AGC_PKC_PKCa_PRKCA_ST	P07949	RET	P17252	PRKCA	S686	R693H	693	Missense	distal	7	no	16.759	16.688	EPSD	CCLE	16.704	Loss
AGC_PKC_PKCa_PRKCA_ST	P07949	RET	P17252	PRKCA	S696	R693H	693	Missense	distal	-3	no	20.184	16.328	EPSD	CCLE	16.704	Loss
AGC_PKC_PKCa_PRKCA_ST	P05556	ITGB1	P17252	PRKCA	T60	G57R	57	Missense	distal	-3	no	13.502	16.763	EPSD	CCLE	16.704	Gain
AGC_PKC_PKCa_PRKCA_ST	P05556	ITGB1	P17252	PRKCA	S61	G57R	57	Missense	distal	-4	no	18.513	18.615	EPSD	CCLE	16.704	Up-regulation
AGC_PKC_PKCa_PRKCA_ST	P05556	ITGB1	P17252	PRKCA	S61	E56G	56	Missense	distal	-5	no	18.513	18.530	EPSD	CCLE	16.704	Up-regulation
AGC_PKC_PKCa_PRKCA_ST	O15519	CFLAR	P17252	PRKCA	S193	P197S	197	Missense	distal	4	no	18.401	18.601	PhosphoSitePlus	CCLE	16.704	Up-regulation
AGC_PKC_PKCa_PRKCA_ST	P08670	VIM	P17252	PRKCA	S2	S8P	8	Missense	distal	6	no	19.646	19.679	EPSD	CCLE	16.704	Up-regulation
AGC_PKC_PKCa_PRKCA_ST	P08670	VIM	P17252	PRKCA	S5	S8P	8	Missense	distal	3	no	17.100	16.960	EPSD;PhosphoSitePlus	CCLE	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	P08670	VIM	P17252	PRKCA	S7	S8P	8	Missense	proximal	1	no	16.941	17.341	EPSD;PhosphoSitePlus	CCLE	16.704	Up-regulation
AGC_PKC_PKCa_PRKCA_ST	P08670	VIM	P17252	PRKCA	S8	S8P	8	Missense	central	0	yes	16.731	0.000	EPSD;PhosphoSitePlus	CCLE	16.704	Loss
AGC_PKC_PKCa_PRKCA_ST	P08670	VIM	P17252	PRKCA	S9	S8P	8	Missense	proximal	-1	no	18.343	18.043	EPSD;PhosphoSitePlus	CCLE	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	P08670	VIM	P17252	PRKCA	S10	S8P	8	Missense	proximal	-2	no	24.413	24.673	PhosphoSitePlus;EPSD	CCLE	16.704	Up-regulation
AGC_PKC_PKCa_PRKCA_ST	P08670	VIM	P17252	PRKCA	S34	Y38H	38	Missense	distal	4	no	16.913	17.274	EPSD	CCLE	16.704	Up-regulation
AGC_PKC_PKCa_PRKCA_ST	P08670	VIM	P17252	PRKCA	S42	Y38H	38	Missense	distal	-4	no	17.403	17.215	EPSD	CCLE	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	P08670	VIM	P17252	PRKCA	S205	N201S	201	Missense	distal	-4	no	17.977	18.307	EPSD	CCLE	16.704	Up-regulation
AGC_PKC_PKCa_PRKCA_ST	Q9UKF7	PITPNC1	P17252	PRKCA	S299	K292R	292	Missense	distal	-7	no	19.762	19.766	PhosphoSitePlus;EPSD	CCLE	16.704	Up-regulation
AGC_PKC_PKCa_PRKCA_ST	P14598	NCF1	P17252	PRKCA	S320	R326H	326	Missense	distal	6	no	18.045	17.968	PhosphoSitePlus;EPSD	CCLE	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	P14598	NCF1	P17252	PRKCA	S328	R326H	326	Missense	proximal	-2	no	24.594	20.040	EPSD;PhosphoSitePlus	CCLE	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	P14598	NCF1	P17252	PRKCA	T356	R354L	354	Missense	proximal	-2	no	18.076	15.388	EPSD	CCLE	16.704	Loss
AGC_PKC_PKCa_PRKCA_ST	P14598	NCF1	P17252	PRKCA	T356	Q357H	357	Missense	proximal	1	no	18.076	17.380	EPSD	CCLE	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	Q03721	KCNC4	P17252	PRKCA	S8	S8P	8	Missense	central	0	yes	18.348	0.000	EPSD	CCLE	16.704	Loss
AGC_PKC_PKCa_PRKCA_ST	Q03721	KCNC4	P17252	PRKCA	S9	S8P	8	Missense	proximal	-1	no	23.446	23.147	EPSD	CCLE	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	Q03721	KCNC4	P17252	PRKCA	S15	S8P	8	Missense	distal	-7	no	19.374	19.371	PhosphoSitePlus;EPSD	CCLE	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	P46940	IQGAP1	P17252	PRKCA	S280	E283K	283	Missense	distal	3	no	17.016	17.632	EPSD	CCLE	16.704	Up-regulation
AGC_PKC_PKCa_PRKCA_ST	P46940	IQGAP1	P17252	PRKCA	S360	P365L	365	Missense	distal	5	no	18.760	18.410	EPSD	CCLE	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	P46940	IQGAP1	P17252	PRKCA	S1227	D1220Y	1220	Missense	distal	-7	no	17.528	17.532	EPSD	CCLE	16.704	Up-regulation
AGC_PKC_PKCa_PRKCA_ST	P46940	IQGAP1	P17252	PRKCA	S1443	D1447N	1447	Missense	distal	4	no	21.080	20.722	PhosphoSitePlus	CCLE	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	P10588	NR2F6	P17252	PRKCA	S83	I84T	84	Missense	proximal	1	no	24.511	23.175	PhosphoSitePlus	CCLE	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	P10588	NR2F6	P17252	PRKCA	S83	F79L	79	Missense	distal	-4	no	24.511	24.138	PhosphoSitePlus	CCLE	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	P10588	NR2F6	P17252	PRKCA	S89	I84T	84	Missense	distal	-5	no	16.237	16.709	EPSD	CCLE	16.704	Gain
AGC_PKC_PKCa_PRKCA_ST	Q9UH77	KLHL3	P17252	PRKCA	S376	A378T	378	Missense	proximal	2	no	17.233	17.121	EPSD	CCLE	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	P11234	RALB	P17252	PRKCA	S50	Y43C	43	Missense	distal	-7	no	20.678	20.664	EPSD	CCLE	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	Q13522	PPP1R1A	P17252	PRKCA	S67	R71Q	71	Missense	distal	4	no	19.017	18.800	PhosphoSitePlus;EPSD	CCLE	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	Q15139	PRKD1	P17252	PRKCA	S420	M424V	424	Missense	distal	4	no	17.272	15.900	EPSD	CCLE	16.704	Loss
AGC_PKC_PKCa_PRKCA_ST	Q15139	PRKD1	P17252	PRKCA	S421	M424V	424	Missense	distal	3	no	18.202	17.617	EPSD	CCLE	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	Q9BR76	CORO1B	P17252	PRKCA	S407	R402Q	402	Missense	distal	-5	no	17.036	16.884	EPSD	CCLE	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	Q13131	PRKAA1	P17252	PRKCA	S496	S494L	494	Missense	proximal	-2	no	17.709	18.322	PhosphoSitePlus	CCLE	16.704	Up-regulation
AGC_PKC_PKCa_PRKCA_ST	Q13131	PRKAA1	P17252	PRKCA	S496	S494W	494	Missense	proximal	-2	no	17.709	19.013	PhosphoSitePlus	CCLE	16.704	Up-regulation
AGC_PKC_PKCa_PRKCA_ST	O75376	NCOR1	P17252	PRKCA	S1695	Y1693H	1693	Missense	proximal	-2	no	16.938	15.112	EPSD	CCLE	16.704	Loss
AGC_PKC_PKCa_PRKCA_ST	O75376	NCOR1	P17252	PRKCA	S1963	S1962C	1962	Missense	proximal	-1	no	17.446	15.173	EPSD	CCLE	16.704	Loss
AGC_PKC_PKCa_PRKCA_ST	O75376	NCOR1	P17252	PRKCA	S2394	P2398L	2398	Missense	distal	4	no	18.118	17.525	EPSD	CCLE	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	O75376	NCOR1	P17252	PRKCA	S2394	M2390L	2390	Missense	distal	-4	no	18.118	17.414	EPSD	CCLE	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	P29350	PTPN6	P17252	PRKCA	S32	S26R	26	Missense	distal	-6	no	20.658	20.731	EPSD	CCLE	16.704	Up-regulation
AGC_PKC_PKCa_PRKCA_ST	P29350	PTPN6	P17252	PRKCA	S582	R581W	581	Missense	proximal	-1	no	16.827	15.242	EPSD	CCLE	16.704	Loss
AGC_PKC_PKCa_PRKCA_ST	P29350	PTPN6	P17252	PRKCA	S591	L592H	592	Missense	proximal	1	no	19.441	18.975	PhosphoSitePlus	CCLE	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	P35869	AHR	P17252	PRKCA	S81	L77P	77	Missense	distal	-4	no	18.258	18.518	EPSD	CCLE	16.704	Up-regulation
AGC_PKC_PKCa_PRKCA_ST	P35611	ADD1	P17252	PRKCA	S353	K348T	348	Missense	distal	-5	no	16.821	16.734	EPSD	CCLE	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	P35611	ADD1	P17252	PRKCA	S404	K403R	403	Missense	proximal	-1	no	20.626	20.569	EPSD	CCLE	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	P35611	ADD1	P17252	PRKCA	S669	A664V	664	Missense	distal	-5	no	17.233	17.149	EPSD	CCLE	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	P35611	ADD1	P17252	PRKCA	S669	R666S	666	Missense	distal	-3	no	17.233	14.363	EPSD	CCLE	16.704	Loss
AGC_PKC_PKCa_PRKCA_ST	P35611	ADD1	P17252	PRKCA	S669	S669R	669	Missense	central	0	yes	17.233	0.000	EPSD	CCLE	16.704	Loss
AGC_PKC_PKCa_PRKCA_ST	Q92681	RSC1A1	P17252	PRKCA	S66	S66P	66	Missense	central	0	yes	17.835	0.000	EPSD	CCLE	16.704	Loss
AGC_PKC_PKCa_PRKCA_ST	P81274	GPSM2	P17252	PRKCA	S408	P401L	401	Missense	distal	-7	no	21.986	21.983	PhosphoSitePlus	CCLE	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	P81274	GPSM2	P17252	PRKCA	S460	K456T	456	Missense	distal	-4	no	16.759	15.869	EPSD	CCLE	16.704	Loss
AGC_PKC_PKCa_PRKCA_ST	Q9NS23	RASSF1	P17252	PRKCA	S2	L7F	7	Missense	distal	5	no	16.902	17.127	EPSD	CCLE	16.704	Up-regulation
AGC_PKC_PKCa_PRKCA_ST	Q13224	GRIN2B	P17252	PRKCA	S1166	S1159G	1159	Missense	distal	-7	no	19.183	19.178	EPSD	CCLE	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	Q96MS0	ROBO3	P17252	PRKCA	S404	R400C	400	Missense	distal	-4	no	19.215	17.872	EPSD	CCLE	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	Q96MS0	ROBO3	P17252	PRKCA	S725	L721I	721	Missense	distal	-4	no	17.882	17.871	EPSD	CCLE	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	Q96MS0	ROBO3	P17252	PRKCA	S1352	N1347K	1347	Missense	distal	-5	no	17.444	17.787	EPSD	CCLE	16.704	Up-regulation
AGC_PKC_PKCa_PRKCA_ST	Q96MS0	ROBO3	P17252	PRKCA	S1353	N1347K	1347	Missense	distal	-6	no	19.296	19.420	EPSD	CCLE	16.704	Up-regulation
AGC_PKC_PKCa_PRKCA_ST	P06239	LCK	P17252	PRKCA	S133	R139Q	139	Missense	distal	6	no	18.873	18.750	EPSD	CCLE	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	P06239	LCK	P17252	PRKCA	S166	A160T	160	Missense	distal	-6	no	18.998	18.910	EPSD	CCLE	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	P32004	L1CAM	P17252	PRKCA	S1230	Y1229S	1229	Missense	proximal	-1	no	19.747	20.196	EPSD	CCLE	16.704	Up-regulation
AGC_PKC_PKCa_PRKCA_ST	O15350	TP73	P17252	PRKCA	S326	A320T	320	Missense	distal	-6	no	19.187	19.098	EPSD	CCLE	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	O15350	TP73	P17252	PRKCA	S471	S477L	477	Missense	distal	6	no	17.254	17.243	EPSD	CCLE	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	P28329	CHAT	P17252	PRKCA	S464	A471V	471	Missense	distal	7	no	18.756	18.701	EPSD	CCLE	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	P28329	CHAT	P17252	PRKCA	S465	A471V	471	Missense	distal	6	no	18.460	18.342	EPSD	CCLE	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	P28329	CHAT	P17252	PRKCA	S473	A471V	471	Missense	proximal	-2	no	18.312	18.555	EPSD	CCLE	16.704	Up-regulation
AGC_PKC_PKCa_PRKCA_ST	P28329	CHAT	P17252	PRKCA	S473	P480F	480	Missense	distal	7	no	18.312	18.212	EPSD	CCLE	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	P28329	CHAT	P17252	PRKCA	S558	A557E	557	Missense	proximal	-1	no	19.146	19.723	EPSD	CCLE	16.704	Up-regulation
AGC_PKC_PKCa_PRKCA_ST	P06401	PGR	P17252	PRKCA	S345	A348G	348	Missense	distal	3	no	15.882	16.840	EPSD	CCLE	16.704	Gain
AGC_PKC_PKCa_PRKCA_ST	Q8N556	AFAP1	P17252	PRKCA	S101	G103R	103	Missense	proximal	2	no	14.027	19.273	EPSD	CCLE	16.704	Gain
AGC_PKC_PKCa_PRKCA_ST	Q8N556	AFAP1	P17252	PRKCA	T524	A519E	519	Missense	distal	-5	no	16.634	16.807	EPSD	CCLE	16.704	Gain
AGC_PKC_PKCa_PRKCA_ST	Q8N556	AFAP1	P17252	PRKCA	S531	A537S	537	Missense	distal	6	no	16.713	16.684	EPSD	CCLE	16.704	Loss
AGC_PKC_PKCa_PRKCA_ST	Q8TD43	TRPM4	P17252	PRKCA	S255	R252C	252	Missense	distal	-3	no	19.561	16.822	EPSD	CCLE	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	Q8TD43	TRPM4	P17252	PRKCA	S1098	S1103F	1103	Missense	distal	5	no	19.660	19.694	EPSD	CCLE	16.704	Up-regulation
AGC_PKC_PKCa_PRKCA_ST	Q14184	DOC2B	P17252	PRKCA	S273	R269C	269	Missense	distal	-4	no	17.391	16.047	EPSD	CCLE	16.704	Loss
AGC_PKC_PKCa_PRKCA_ST	Q14184	DOC2B	P17252	PRKCA	S273	E266G	266	Missense	distal	-7	no	17.391	17.394	EPSD	CCLE	16.704	Up-regulation
AGC_PKC_PKCa_PRKCA_ST	Q12959	DLG1	P17252	PRKCA	S347	G344R	344	Missense	distal	-3	no	14.350	17.612	EPSD	CCLE	16.704	Gain
AGC_PKC_PKCa_PRKCA_ST	Q12959	DLG1	P17252	PRKCA	S575	R582Q	582	Missense	distal	7	no	18.992	18.987	EPSD	CCLE	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	Q12959	DLG1	P17252	PRKCA	S579	R582Q	582	Missense	distal	3	no	21.263	18.810	EPSD	CCLE	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	Q12959	DLG1	P17252	PRKCA	S583	R582Q	582	Missense	proximal	-1	no	18.178	17.360	EPSD	CCLE	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	Q12959	DLG1	P17252	PRKCA	S643	R645H	645	Missense	proximal	2	no	18.485	13.461	EPSD	CCLE	16.704	Loss
AGC_PKC_PKCa_PRKCA_ST	Q12959	DLG1	P17252	PRKCA	S795	A800T	800	Missense	distal	5	no	19.268	18.990	EPSD	CCLE	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	P41180	CASR	P17252	PRKCA	T888	T888A	888	Missense	central	0	yes	17.986	0.000	PhosphoSitePlus	CCLE	16.704	Loss
AGC_PKC_PKCa_PRKCA_ST	P41180	CASR	P17252	PRKCA	S895	T888A	888	Missense	distal	-7	no	19.647	19.652	EPSD	CCLE	16.704	Up-regulation
AGC_PKC_PKCa_PRKCA_ST	P41180	CASR	P17252	PRKCA	S899	S905F	905	Missense	distal	6	no	17.285	17.243	EPSD	CCLE	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	P41180	CASR	P17252	PRKCA	S900	S905F	905	Missense	distal	5	no	17.164	17.198	EPSD	CCLE	16.704	Up-regulation
AGC_PKC_PKCa_PRKCA_ST	P41180	CASR	P17252	PRKCA	S901	S905F	905	Missense	distal	4	no	16.908	16.546	EPSD	CCLE	16.704	Loss
AGC_PKC_PKCa_PRKCA_ST	Q99623	PHB2	P17252	PRKCA	S105	Q100E	100	Missense	distal	-5	no	16.893	16.738	EPSD	CCLE	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	O14939	PLD2	P17252	PRKCA	S155	R149G	149	Missense	distal	-6	no	18.533	18.426	EPSD	CCLE	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	O14939	PLD2	P17252	PRKCA	T488	S481L	481	Missense	distal	-7	no	16.907	16.901	EPSD	CCLE	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	O14939	PLD2	P17252	PRKCA	T488	S484F	484	Missense	distal	-4	no	16.907	16.849	EPSD	CCLE	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	O14939	PLD2	P17252	PRKCA	T488	R490C	490	Missense	proximal	2	no	16.907	12.557	EPSD	CCLE	16.704	Loss
AGC_PKC_PKCa_PRKCA_ST	O14939	PLD2	P17252	PRKCA	S814	R816W	816	Missense	proximal	2	no	18.723	13.283	EPSD	CCLE	16.704	Loss
AGC_PKC_PKCa_PRKCA_ST	Q5JVS0	HABP4	P17252	PRKCA	S108	S108N	108	Missense	central	0	yes	16.850	0.000	EPSD	CCLE	16.704	Loss
AGC_PKC_PKCa_PRKCA_ST	Q9BZL6	PRKD2	P17252	PRKCA	S197	A202T	202	Missense	distal	5	no	17.772	17.493	EPSD	CCLE	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	Q9BZL6	PRKD2	P17252	PRKCA	S198	A202T	202	Missense	distal	4	no	19.167	18.720	EPSD	CCLE	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	Q9BZL6	PRKD2	P17252	PRKCA	S206	A202T	202	Missense	distal	-4	no	18.452	17.704	EPSD	CCLE	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	Q13002	GRIK2	P17252	PRKCA	S868	R866T	866	Missense	proximal	-2	no	22.309	19.415	PhosphoSitePlus	CCLE	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	Q09472	EP300	P17252	PRKCA	S384	M379T	379	Missense	distal	-5	no	16.999	17.067	EPSD	CCLE	16.704	Up-regulation
AGC_PKC_PKCa_PRKCA_ST	Q09472	EP300	P17252	PRKCA	T1135	C1142Y	1142	Missense	distal	7	no	18.975	19.146	EPSD	CCLE	16.704	Up-regulation
AGC_PKC_PKCa_PRKCA_ST	Q09472	EP300	P17252	PRKCA	S1295	F1288L	1288	Missense	distal	-7	no	21.387	21.390	EPSD	CCLE	16.704	Up-regulation
AGC_PKC_PKCa_PRKCA_ST	Q09472	EP300	P17252	PRKCA	S1730	R1737H	1737	Missense	distal	7	no	18.150	18.079	EPSD	CCLE	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	Q09472	EP300	P17252	PRKCA	S1734	R1737H	1737	Missense	distal	3	no	21.175	20.463	EPSD	CCLE	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	Q09472	EP300	P17252	PRKCA	S2315	R2308H	2308	Missense	distal	-7	no	16.834	16.827	EPSD	CCLE	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	O14920	IKBKB	P17252	PRKCA	S2	T8R	8	Missense	distal	6	no	17.577	17.697	EPSD	CCLE	16.704	Up-regulation
AGC_PKC_PKCa_PRKCA_ST	O14920	IKBKB	P17252	PRKCA	S6	T8R	8	Missense	proximal	2	no	17.791	22.601	EPSD	CCLE	16.704	Up-regulation
AGC_PKC_PKCa_PRKCA_ST	O75144	ICOSLG	P17252	PRKCA	S15	S14G	14	Missense	proximal	-1	no	16.557	16.805	EPSD	CCLE	16.704	Gain
AGC_PKC_PKCa_PRKCA_ST	Q8N0W4	NLGN4X	P17252	PRKCA	T249	G243E	243	Missense	distal	-6	no	17.149	17.182	EPSD	CCLE	16.704	Up-regulation
AGC_PKC_PKCa_PRKCA_ST	P49407	ARRB1	P17252	PRKCA	S163	I158T	158	Missense	distal	-5	no	21.728	22.200	PhosphoSitePlus	CCLE	16.704	Up-regulation
AGC_PKC_PKCa_PRKCA_ST	P41091	EIF2S3	P17252	PRKCA	S444	E448K	448	Missense	distal	4	no	17.904	18.443	EPSD	CCLE	16.704	Up-regulation
AGC_PKC_PKCa_PRKCA_ST	Q13769	THOC5	P17252	PRKCA	T322	E317A	317	Missense	distal	-5	no	19.085	18.912	EPSD	CCLE	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	Q13769	THOC5	P17252	PRKCA	T322	E317K	317	Missense	distal	-5	no	19.085	19.379	EPSD	CCLE	16.704	Up-regulation
AGC_PKC_PKCa_PRKCA_ST	Q12791	KCNMA1	P17252	PRKCA	S22	S22G	22	Missense	central	0	yes	20.823	0.000	EPSD	CCLE	16.704	Loss
AGC_PKC_PKCa_PRKCA_ST	Q12791	KCNMA1	P17252	PRKCA	S1200	S1200C	1200	Missense	central	0	yes	20.403	0.000	PhosphoSitePlus	CCLE	16.704	Loss
AGC_PKC_PKCa_PRKCA_ST	P43119	PTGIR	P17252	PRKCA	S14	T19N	19	Missense	distal	5	no	19.683	19.638	EPSD	CCLE	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	Q01970	PLCB3	P17252	PRKCA	S26	I29V	29	Missense	distal	3	no	21.962	22.657	EPSD	CCLE	16.704	Up-regulation
AGC_PKC_PKCa_PRKCA_ST	Q01970	PLCB3	P17252	PRKCA	S474	A475T	475	Missense	proximal	1	no	17.287	16.816	EPSD	CCLE	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	O94759	TRPM2	P17252	PRKCA	S612	S611F	611	Missense	proximal	-1	no	17.161	16.453	EPSD	CCLE	16.704	Loss
AGC_PKC_PKCa_PRKCA_ST	P13498	CYBA	P17252	PRKCA	T147	P142R	142	Missense	distal	-5	no	18.137	18.239	PhosphoSitePlus	CCLE	16.704	Up-regulation
AGC_PKC_PKCa_PRKCA_ST	Q9C0K0	BCL11B	P17252	PRKCA	S101	S97I	97	Missense	distal	-4	no	17.717	17.275	EPSD	CCLE	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	Q9C0K0	BCL11B	P17252	PRKCA	S364	D362G	362	Missense	proximal	-2	no	19.032	19.579	EPSD	CCLE	16.704	Up-regulation
AGC_PKC_PKCa_PRKCA_ST	Q9C0K0	BCL11B	P17252	PRKCA	S749	S744W	744	Missense	distal	-5	no	17.502	17.615	EPSD	CCLE	16.704	Up-regulation
AGC_PKC_PKCa_PRKCA_ST	Q9C0K0	BCL11B	P17252	PRKCA	S788	R786W	786	Missense	proximal	-2	no	21.436	19.438	EPSD	CCLE	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	Q9C0K0	BCL11B	P17252	PRKCA	S789	R786W	786	Missense	distal	-3	no	19.514	17.160	EPSD	CCLE	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	P50552	VASP	P17252	PRKCA	T278	T278M	278	Missense	central	0	yes	17.590	0.000	EPSD	CCLE	16.704	Loss
AGC_PKC_PKCa_PRKCA_ST	P50552	VASP	P17252	PRKCA	S322	S324C	324	Missense	proximal	2	no	16.500	16.770	EPSD	CCLE	16.704	Gain
AGC_PKC_PKCa_PRKCA_ST	Q14524	SCN5A	P17252	PRKCA	S571	P564S	564	Missense	distal	-7	no	22.789	22.792	EPSD	CCLE	16.704	Up-regulation
AGC_PKC_PKCa_PRKCA_ST	Q14524	SCN5A	P17252	PRKCA	S1920	R1919H	1919	Missense	proximal	-1	no	20.164	19.841	EPSD	CCLE	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	P35900	KRT20	P17252	PRKCA	S11	A18V	18	Missense	distal	7	no	18.157	18.103	EPSD	CCLE	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	P35900	KRT20	P17252	PRKCA	S13	A18V	18	Missense	distal	5	no	18.842	18.458	PhosphoSitePlus	CCLE	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	P35900	KRT20	P17252	PRKCA	S14	A18V	18	Missense	distal	4	no	16.717	15.379	EPSD	CCLE	16.704	Loss
AGC_PKC_PKCa_PRKCA_ST	P35900	KRT20	P17252	PRKCA	S83	Y84H	84	Missense	proximal	1	no	18.907	18.456	EPSD	CCLE	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	P35900	KRT20	P17252	PRKCA	S118	S118N	118	Missense	central	0	yes	16.820	0.000	EPSD	CCLE	16.704	Loss
AGC_PKC_PKCa_PRKCA_ST	Q71U36	TUBA1A	P17252	PRKCA	S38	I42T	42	Missense	distal	4	no	16.171	17.185	EPSD	CCLE	16.704	Gain
AGC_PKC_PKCa_PRKCA_ST	Q15762	CD226	P17252	PRKCA	S329	R335T	335	Missense	distal	6	no	16.809	16.689	PhosphoSitePlus	CCLE	16.704	Loss
AGC_PKC_PKCa_PRKCA_ST	P49840	GSK3A	P17252	PRKCA	S52	T46S	46	Missense	distal	-6	no	17.680	17.806	EPSD	CCLE	16.704	Up-regulation
AGC_PKC_PKCa_PRKCA_ST	P14416	DRD2	P17252	PRKCA	S147	R150H	150	Missense	distal	3	no	22.313	21.600	EPSD	CCLE	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	P14416	DRD2	P17252	PRKCA	S148	R150H	150	Missense	proximal	2	no	22.832	17.809	EPSD	CCLE	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	P14416	DRD2	P17252	PRKCA	T225	V223I	223	Missense	proximal	-2	no	21.887	21.141	EPSD	CCLE	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	P14416	DRD2	P17252	PRKCA	S228	V223I	223	Missense	distal	-5	no	18.941	18.933	EPSD;PhosphoSitePlus	CCLE	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	P14416	DRD2	P17252	PRKCA	S229	V223I	223	Missense	distal	-6	no	17.910	17.926	PhosphoSitePlus;EPSD	CCLE	16.704	Up-regulation
AGC_PKC_PKCa_PRKCA_ST	Q96QS3	ARX	P17252	PRKCA	S530	A534T	534	Missense	distal	4	no	19.562	19.115	EPSD	CCLE	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	Q96QS3	ARX	P17252	PRKCA	S531	A534T	534	Missense	distal	3	no	17.351	17.112	EPSD	CCLE	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	P22460	KCNA5	P17252	PRKCA	T15	G11D	11	Missense	distal	-4	no	21.251	20.481	PhosphoSitePlus	CCLE	16.704	Down-regulation
AGC_PKC_PKCa_PRKCA_ST	P22460	KCNA5	P17252	PRKCA	S414	V407L	407	Missense	distal	-7	no	17.936	17.939	EPSD	CCLE	16.704	Up-regulation
AGC_PKC_PKCa_PRKCA_ST	P22460	KCNA5	P17252	PRKCA	S430	T426N	426	Missense	distal	-4	no	17.446	17.778	EPSD	CCLE	16.704	Up-regulation
AGC_PKC_PKCa_PRKCA_ST	Q92837	FRAT1	P17252	PRKCA	S179	R180H	180	Missense	proximal	1	no	16.801	15.988	EPSD	CCLE	16.704	Loss
TK_Src_SRM_Y	Q13882	PTK6	Q9H3Y6	SRMS	Y66	R70K	70	Missense	distal	4	no	2.496	2.472	EPSD	CCLE	1.179	Down-regulation
Other_IKK_IKBKB_ST	Q99704	DOK1	O14920	IKBKB	S302	L295M	295	Missense	distal	-7	no	20.031	22.393	EPSD	CCLE	16.613	Up-regulation
Other_IKK_IKBKB_ST	Q04206	RELA	O14920	IKBKB	S468	A467V	467	Missense	proximal	-1	no	24.405	24.824	EPSD;PhosphoSitePlus	CCLE	16.613	Up-regulation
Other_IKK_IKBKB_ST	Q04206	RELA	O14920	IKBKB	S472	A467V	467	Missense	distal	-5	no	20.019	19.670	EPSD	CCLE	16.613	Down-regulation
Other_IKK_IKBKB_ST	Q04206	RELA	O14920	IKBKB	S529	S535A	535	Missense	distal	6	no	15.913	17.127	EPSD	CCLE	16.613	Gain
Other_IKK_IKBKB_ST	Q04206	RELA	O14920	IKBKB	S536	S535A	535	Missense	proximal	-1	no	35.152	34.995	EPSD;PhosphoSitePlus	CCLE	16.613	Down-regulation
Other_IKK_IKBKB_ST	O15350	TP73	O14920	IKBKB	S471	S477L	477	Missense	distal	6	no	22.729	23.936	PhosphoSitePlus	CCLE	16.613	Up-regulation
Other_IKK_IKBKB_ST	Q9H3D4	TP63	O14920	IKBKB	S30	F29L	29	Missense	proximal	-1	no	26.086	25.477	EPSD	CCLE	16.613	Down-regulation
Other_IKK_IKBKB_ST	P19838	NFKB1	O14920	IKBKB	S449	G445C	445	Missense	distal	-4	no	18.785	19.362	EPSD	CCLE	16.613	Up-regulation
Other_IKK_IKBKB_ST	P01100	FOS	O14920	IKBKB	S281	S278Y	278	Missense	distal	-3	no	18.030	17.456	EPSD	CCLE	16.613	Down-regulation
Other_IKK_IKBKB_ST	P01100	FOS	O14920	IKBKB	S308	P315R	315	Missense	distal	7	no	27.703	28.030	PhosphoSitePlus	CCLE	16.613	Up-regulation
Other_IKK_IKBKB_ST	Q01201	RELB	O14920	IKBKB	S37	P30R	30	Missense	distal	-7	no	14.943	16.685	EPSD	CCLE	16.613	Gain
Other_IKK_IKBKB_ST	Q92574	TSC1	O14920	IKBKB	S205	S208N	208	Missense	distal	3	no	23.388	22.613	EPSD	CCLE	16.613	Down-regulation
Other_IKK_IKBKB_ST	Q92574	TSC1	O14920	IKBKB	S276	S278F	278	Missense	proximal	2	no	18.671	18.452	EPSD	CCLE	16.613	Down-regulation
Other_IKK_IKBKB_ST	Q92574	TSC1	O14920	IKBKB	S295	T294A	294	Missense	proximal	-1	no	21.638	21.511	EPSD	CCLE	16.613	Down-regulation
Other_IKK_IKBKB_ST	Q92574	TSC1	O14920	IKBKB	S472	E469G	469	Missense	distal	-3	no	24.119	23.815	EPSD	CCLE	16.613	Down-regulation
Other_IKK_IKBKB_ST	Q92574	TSC1	O14920	IKBKB	S521	A523T	523	Missense	proximal	2	no	17.930	17.766	EPSD	CCLE	16.613	Down-regulation
Other_IKK_IKBKB_ST	Q92574	TSC1	O14920	IKBKB	S526	A523T	523	Missense	distal	-3	no	19.060	19.009	EPSD	CCLE	16.613	Down-regulation
Other_IKK_IKBKB_ST	Q92574	TSC1	O14920	IKBKB	S530	A523T	523	Missense	distal	-7	no	19.116	18.685	EPSD	CCLE	16.613	Down-regulation
Other_IKK_IKBKB_ST	Q92574	TSC1	O14920	IKBKB	S1073	P1075R	1075	Missense	proximal	2	no	22.822	22.975	EPSD	CCLE	16.613	Up-regulation
Other_IKK_IKBKB_ST	Q92574	TSC1	O14920	IKBKB	S1080	P1075R	1075	Missense	distal	-5	no	21.410	21.348	EPSD	CCLE	16.613	Down-regulation
Other_IKK_IKBKB_ST	O95999	BCL10	O14920	IKBKB	S121	D127N	127	Missense	distal	6	no	16.148	16.793	EPSD	CCLE	16.613	Gain
Other_IKK_IKBKB_ST	O95999	BCL10	O14920	IKBKB	S134	D127N	127	Missense	distal	-7	no	20.709	21.549	EPSD;PhosphoSitePlus	CCLE	16.613	Up-regulation
Other_IKK_IKBKB_ST	P42858	HTT	O14920	IKBKB	S118	V115L	115	Missense	distal	-3	no	19.664	19.583	EPSD	CCLE	16.613	Down-regulation
Other_IKK_IKBKB_ST	P42858	HTT	O14920	IKBKB	S1111	E1114A	1114	Missense	distal	3	no	20.466	19.265	EPSD	CCLE	16.613	Down-regulation
Other_IKK_IKBKB_ST	P42858	HTT	O14920	IKBKB	S2651	P2653S	2653	Missense	proximal	2	no	16.872	17.129	EPSD	CCLE	16.613	Up-regulation
Other_IKK_IKBKB_ST	P42858	HTT	O14920	IKBKB	S2655	P2653S	2653	Missense	proximal	-2	no	21.289	20.403	EPSD	CCLE	16.613	Down-regulation
Other_IKK_IKBKB_ST	P42858	HTT	O14920	IKBKB	S2655	H2662Y	2662	Missense	distal	7	no	21.289	20.639	EPSD	CCLE	16.613	Down-regulation
Other_IKK_IKBKB_ST	P19438	TNFRSF1A	O14920	IKBKB	S381	D382N	382	Missense	proximal	1	no	17.341	17.799	PhosphoSitePlus	CCLE	16.613	Up-regulation
Other_IKK_IKBKB_ST	P19438	TNFRSF1A	O14920	IKBKB	S402	S402N	402	Missense	central	0	yes	17.485	0.000	EPSD	CCLE	16.613	Loss
Other_IKK_IKBKB_ST	Q6P2E9	EDC4	O14920	IKBKB	S613	G618S	618	Missense	distal	5	no	21.529	24.841	EPSD	CCLE	16.613	Up-regulation
Other_IKK_IKBKB_ST	Q6P2E9	EDC4	O14920	IKBKB	S613	S620G	620	Missense	distal	7	no	21.529	20.655	EPSD	CCLE	16.613	Down-regulation
Other_IKK_IKBKB_ST	Q6P2E9	EDC4	O14920	IKBKB	S621	G618S	618	Missense	distal	-3	no	23.268	23.534	EPSD	CCLE	16.613	Up-regulation
Other_IKK_IKBKB_ST	Q6P2E9	EDC4	O14920	IKBKB	S621	S620G	620	Missense	proximal	-1	no	23.268	23.657	EPSD	CCLE	16.613	Up-regulation
Other_IKK_IKBKB_ST	Q6P2E9	EDC4	O14920	IKBKB	S621	S622N	622	Missense	proximal	1	no	23.268	23.982	EPSD	CCLE	16.613	Up-regulation
Other_IKK_IKBKB_ST	Q6P2E9	EDC4	O14920	IKBKB	S622	G618S	618	Missense	distal	-4	no	20.619	26.894	EPSD	CCLE	16.613	Up-regulation
Other_IKK_IKBKB_ST	Q6P2E9	EDC4	O14920	IKBKB	S622	S620G	620	Missense	proximal	-2	no	20.619	21.332	EPSD	CCLE	16.613	Up-regulation
Other_IKK_IKBKB_ST	Q6P2E9	EDC4	O14920	IKBKB	S622	S622N	622	Missense	central	0	yes	20.619	0.000	EPSD	CCLE	16.613	Loss
Other_IKK_IKBKB_ST	Q6P2E9	EDC4	O14920	IKBKB	S623	G618S	618	Missense	distal	-5	no	24.194	24.322	EPSD	CCLE	16.613	Up-regulation
Other_IKK_IKBKB_ST	Q6P2E9	EDC4	O14920	IKBKB	S623	S620G	620	Missense	distal	-3	no	24.194	23.927	EPSD	CCLE	16.613	Down-regulation
Other_IKK_IKBKB_ST	Q6P2E9	EDC4	O14920	IKBKB	S623	S622N	622	Missense	proximal	-1	no	24.194	24.049	EPSD	CCLE	16.613	Down-regulation
Other_IKK_IKBKB_ST	Q6P2E9	EDC4	O14920	IKBKB	S624	G618S	618	Missense	distal	-6	no	19.488	20.185	EPSD	CCLE	16.613	Up-regulation
Other_IKK_IKBKB_ST	Q6P2E9	EDC4	O14920	IKBKB	S624	S620G	620	Missense	distal	-4	no	19.488	13.213	EPSD	CCLE	16.613	Loss
Other_IKK_IKBKB_ST	Q6P2E9	EDC4	O14920	IKBKB	S624	S622N	622	Missense	proximal	-2	no	19.488	19.406	EPSD	CCLE	16.613	Down-regulation
Other_IKK_IKBKB_ST	Q6P2E9	EDC4	O14920	IKBKB	S670	A675E	675	Missense	distal	5	no	23.996	25.350	EPSD	CCLE	16.613	Up-regulation
Other_IKK_IKBKB_ST	Q6P2E9	EDC4	O14920	IKBKB	S672	A675E	675	Missense	distal	3	no	18.921	20.122	EPSD	CCLE	16.613	Up-regulation
Other_IKK_IKBKB_ST	Q6P2E9	EDC4	O14920	IKBKB	S676	A675E	675	Missense	proximal	-1	no	19.512	19.637	EPSD	CCLE	16.613	Up-regulation
Other_IKK_IKBKB_ST	Q6P2E9	EDC4	O14920	IKBKB	S809	A813S	813	Missense	distal	4	no	17.684	20.236	EPSD	CCLE	16.613	Up-regulation
Other_IKK_IKBKB_ST	Q6P2E9	EDC4	O14920	IKBKB	S967	R965Q	965	Missense	proximal	-2	no	18.309	18.716	EPSD	CCLE	16.613	Up-regulation
Other_IKK_IKBKB_ST	Q9Y6K9	IKBKG	O14920	IKBKB	S85	S85C	85	Missense	central	0	yes	22.111	0.000	EPSD;PhosphoSitePlus	CCLE	16.613	Loss
Other_IKK_IKBKB_ST	Q9Y6K9	IKBKG	O14920	IKBKB	S208	M215I	215	Missense	distal	7	no	22.736	21.326	EPSD	CCLE	16.613	Down-regulation
Other_IKK_IKBKB_ST	P21580	TNFAIP3	O14920	IKBKB	S573	H577P	577	Missense	distal	4	no	20.858	22.128	EPSD	CCLE	16.613	Up-regulation
Other_IKK_IKBKB_ST	P21580	TNFAIP3	O14920	IKBKB	S645	A639S	639	Missense	distal	-6	no	18.626	18.582	EPSD	CCLE	16.613	Down-regulation
Other_IKK_IKBKB_ST	P21580	TNFAIP3	O14920	IKBKB	S645	S649A	649	Missense	distal	4	no	18.626	16.074	EPSD	CCLE	16.613	Loss
Other_IKK_IKBKB_ST	Q9Y4G8	RAPGEF2	O14920	IKBKB	S1089	S1089F	1089	Missense	central	0	yes	27.957	0.000	EPSD	CCLE	16.613	Loss
Other_IKK_IKBKB_ST	Q9Y4G8	RAPGEF2	O14920	IKBKB	S1095	S1089F	1089	Missense	distal	-6	no	19.879	18.731	EPSD	CCLE	16.613	Down-regulation
Other_IKK_IKBKB_ST	Q9Y4G8	RAPGEF2	O14920	IKBKB	S1166	H1168R	1168	Missense	proximal	2	no	19.186	19.207	EPSD	CCLE	16.613	Up-regulation
Other_IKK_IKBKB_ST	Q9Y4G8	RAPGEF2	O14920	IKBKB	S1166	R1172G	1172	Missense	distal	6	no	19.186	20.239	EPSD	CCLE	16.613	Up-regulation
Other_IKK_IKBKB_ST	Q9Y4G8	RAPGEF2	O14920	IKBKB	S1204	P1197A	1197	Missense	distal	-7	no	15.578	17.649	EPSD	CCLE	16.613	Gain
Other_IKK_IKBKB_ST	Q9Y4G8	RAPGEF2	O14920	IKBKB	S1487	P1480H	1480	Missense	distal	-7	no	17.346	17.894	EPSD	CCLE	16.613	Up-regulation
Other_IKK_IKBKB_ST	P35568	IRS1	O14920	IKBKB	S270	S273L	273	Missense	distal	3	no	16.872	13.920	EPSD	CCLE	16.613	Loss
Other_IKK_IKBKB_ST	P35568	IRS1	O14920	IKBKB	S274	S273L	273	Missense	proximal	-1	no	20.210	20.056	EPSD	CCLE	16.613	Down-regulation
Other_IKK_IKBKB_ST	P35568	IRS1	O14920	IKBKB	S295	R302Q	302	Missense	distal	7	no	17.269	17.438	EPSD	CCLE	16.613	Up-regulation
Other_IKK_IKBKB_ST	P35568	IRS1	O14920	IKBKB	S312	A314D	314	Missense	proximal	2	no	24.537	24.148	PhosphoSitePlus	CCLE	16.613	Down-regulation
Other_IKK_IKBKB_ST	P35568	IRS1	O14920	IKBKB	S380	S374Y	374	Missense	distal	-6	no	18.081	16.734	EPSD	CCLE	16.613	Down-regulation
Other_IKK_IKBKB_ST	P35568	IRS1	O14920	IKBKB	S398	T403P	403	Missense	distal	5	no	23.451	23.972	EPSD	CCLE	16.613	Up-regulation
Other_IKK_IKBKB_ST	P35568	IRS1	O14920	IKBKB	S402	T403P	403	Missense	proximal	1	no	19.297	21.059	EPSD	CCLE	16.613	Up-regulation
Other_IKK_IKBKB_ST	P35568	IRS1	O14920	IKBKB	S531	P532S	532	Missense	proximal	1	no	20.262	19.200	EPSD	CCLE	16.613	Down-regulation
Other_IKK_IKBKB_ST	P35568	IRS1	O14920	IKBKB	S581	V577M	577	Missense	distal	-4	no	14.731	25.493	EPSD	CCLE	16.613	Gain
Other_IKK_IKBKB_ST	P35568	IRS1	O14920	IKBKB	S1037	A1032T	1032	Missense	distal	-5	no	17.849	17.916	EPSD	CCLE	16.613	Up-regulation
Other_IKK_IKBKB_ST	P35568	IRS1	O14920	IKBKB	S1037	M1031T	1031	Missense	distal	-6	no	17.849	17.420	EPSD	CCLE	16.613	Down-regulation
Other_IKK_IKBKB_ST	P35568	IRS1	O14920	IKBKB	S1109	S1105F	1105	Missense	distal	-4	no	18.803	12.568	EPSD	CCLE	16.613	Loss
Other_IKK_IKBKB_ST	P35568	IRS1	O14920	IKBKB	S1131	E1136K	1136	Missense	distal	5	no	16.828	17.690	EPSD	CCLE	16.613	Up-regulation
Other_IKK_IKBKB_ST	Q7Z434	MAVS	O14920	IKBKB	S192	L190Q	190	Missense	proximal	-2	no	23.226	22.637	EPSD	CCLE	16.613	Down-regulation
Other_IKK_IKBKB_ST	Q7Z434	MAVS	O14920	IKBKB	S217	S217C	217	Missense	central	0	yes	21.264	0.000	EPSD	CCLE	16.613	Loss
Other_IKK_IKBKB_ST	Q7Z434	MAVS	O14920	IKBKB	S275	A278T	278	Missense	distal	3	no	19.636	20.084	EPSD	CCLE	16.613	Up-regulation
Other_IKK_IKBKB_ST	Q16875	PFKFB3	O14920	IKBKB	S269	R264L	264	Missense	distal	-5	no	25.228	25.202	PhosphoSitePlus	CCLE	16.613	Down-regulation
Other_IKK_IKBKB_ST	Q16875	PFKFB3	O14920	IKBKB	S485	A489D	489	Missense	distal	4	no	21.721	21.421	EPSD	CCLE	16.613	Down-regulation
Other_IKK_IKBKB_ST	P20749	BCL3	O14920	IKBKB	S382	R388H	388	Missense	distal	6	no	16.631	16.641	EPSD	CCLE	16.613	Up-regulation
Other_IKK_IKBKB_ST	P20749	BCL3	O14920	IKBKB	S386	R388H	388	Missense	proximal	2	no	18.533	18.511	EPSD	CCLE	16.613	Down-regulation
Other_IKK_IKBKB_ST	P20749	BCL3	O14920	IKBKB	S386	S390G	390	Missense	distal	4	no	18.533	13.632	EPSD	CCLE	16.613	Loss
Other_IKK_IKBKB_ST	Q96CV9	OPTN	O14920	IKBKB	S7	E13D	13	Missense	distal	6	no	20.135	19.474	EPSD	CCLE	16.613	Down-regulation
Other_IKK_IKBKB_ST	Q96CV9	OPTN	O14920	IKBKB	S281	E288K	288	Missense	distal	7	no	16.909	16.613	EPSD	CCLE	16.613	Down-regulation
Other_IKK_IKBKB_ST	Q96CV9	OPTN	O14920	IKBKB	S526	T525A	525	Missense	proximal	-1	no	17.673	17.546	EPSD	CCLE	16.613	Down-regulation
Other_IKK_IKBKB_ST	Q96CV9	OPTN	O14920	IKBKB	S526	Q530K	530	Missense	distal	4	no	17.673	17.320	EPSD	CCLE	16.613	Down-regulation
Other_IKK_IKBKB_ST	O43524	FOXO3	O14920	IKBKB	S438	R444C	444	Missense	distal	6	no	16.337	17.435	EPSD	CCLE	16.613	Gain
Other_IKK_IKBKB_ST	Q13568	IRF5	O14920	IKBKB	S156	L157P	157	Missense	proximal	1	no	18.586	18.878	EPSD	CCLE	16.613	Up-regulation
CAMK_MAPKAPK_MNK_MKNK1_ST	Q9NP80	PNPLA8	Q9BUB5	MKNK1	S106	V111G	111	Missense	distal	5	no	10.135	10.465	EPSD	CCLE	8.316	Up-regulation
CAMK_MAPKAPK_MNK_MKNK1_ST	P23246	SFPQ	Q9BUB5	MKNK1	S379	R376F	376	Missense	distal	-3	no	9.135	6.480	EPSD	CCLE	8.316	Loss
CAMK_MAPKAPK_MNK_MKNK1_ST	P09651	HNRNPA1	Q9BUB5	MKNK1	S142	R146G	146	Missense	distal	4	no	8.361	7.073	EPSD	CCLE	8.316	Loss
CAMK_MAPKAPK_MNK_MKNK1_ST	P09651	HNRNPA1	Q9BUB5	MKNK1	S190	E185Q	185	Missense	distal	-5	no	9.206	9.226	EPSD	CCLE	8.316	Up-regulation
CAMK_MAPKAPK_MNK_MKNK1_ST	P09651	HNRNPA1	Q9BUB5	MKNK1	S192	E185Q	185	Missense	distal	-7	no	14.039	13.876	PhosphoSitePlus;EPSD	CCLE	8.316	Down-regulation
CAMK_MAPKAPK_MNK_MKNK1_ST	P09651	HNRNPA1	Q9BUB5	MKNK1	S264	S269R	269	Missense	distal	5	no	8.768	8.561	EPSD	CCLE	8.316	Down-regulation
CAMK_MAPKAPK_MNK_MKNK1_ST	O43597	SPRY2	Q9BUB5	MKNK1	S112	P106R	106	Missense	distal	-6	no	14.586	14.596	PhosphoSitePlus;EPSD	CCLE	8.316	Up-regulation
CAMK_MAPKAPK_MNK_MKNK1_ST	O43597	SPRY2	Q9BUB5	MKNK1	S197	C201S	201	Missense	distal	4	no	5.454	8.648	EPSD	CCLE	8.316	Gain
Other_Aur_AurB_ST	Q9NQS7	INCENP	Q96GD4	AURKB	S91	R88C	88	Missense	distal	-3	no	0.078	0.071	EPSD	CCLE	0.010	Down-regulation
Other_Aur_AurB_ST	Q9NQS7	INCENP	Q96GD4	AURKB	S93	R88C	88	Missense	distal	-5	no	0.010	0.008	EPSD	CCLE	0.010	Loss
Other_Aur_AurB_ST	Q9NQS7	INCENP	Q96GD4	AURKB	S94	R88C	88	Missense	distal	-6	no	0.070	0.069	EPSD	CCLE	0.010	Down-regulation
Other_Aur_AurB_ST	Q9NQS7	INCENP	Q96GD4	AURKB	S336	K341R	341	Missense	distal	5	no	0.078	0.076	EPSD	CCLE	0.010	Down-regulation
Other_Aur_AurB_ST	Q9NQS7	INCENP	Q96GD4	AURKB	T343	K341R	341	Missense	proximal	-2	no	0.013	0.072	EPSD	CCLE	0.010	Up-regulation
Other_Aur_AurB_ST	Q9NQS7	INCENP	Q96GD4	AURKB	T892	R887C	887	Missense	distal	-5	no	0.018	0.016	EPSD;PhosphoSitePlus	CCLE	0.010	Down-regulation
Other_Aur_AurB_ST	Q9NQS7	INCENP	Q96GD4	AURKB	S893	R887C	887	Missense	distal	-6	no	0.075	0.074	EPSD;PhosphoSitePlus	CCLE	0.010	Down-regulation
Other_Aur_AurB_ST	Q14980	NUMA1	Q96GD4	AURKB	S1162	R1160W	1160	Missense	proximal	-2	no	0.072	0.002	EPSD	CCLE	0.010	Loss
Other_Aur_AurB_ST	Q14980	NUMA1	Q96GD4	AURKB	S1162	S1156P	1156	Missense	distal	-6	no	0.072	0.071	EPSD	CCLE	0.010	Down-regulation
Other_Aur_AurB_ST	Q14980	NUMA1	Q96GD4	AURKB	S1287	R1291W	1291	Missense	distal	4	no	0.010	0.009	EPSD	CCLE	0.010	Loss
Other_Aur_AurB_ST	Q14980	NUMA1	Q96GD4	AURKB	S1288	R1291W	1291	Missense	distal	3	no	0.070	0.071	EPSD	CCLE	0.010	Up-regulation
Other_Aur_AurB_ST	Q14980	NUMA1	Q96GD4	AURKB	S1432	K1430R	1430	Missense	proximal	-2	no	0.013	0.072	EPSD	CCLE	0.010	Up-regulation
Other_Aur_AurB_ST	Q14980	NUMA1	Q96GD4	AURKB	T1879	T1879A	1879	Missense	central	0	yes	0.064	0.000	EPSD	CCLE	0.010	Loss
Other_Aur_AurB_ST	Q9H0H5	RACGAP1	Q96GD4	AURKB	S313	R317L	317	Missense	distal	4	no	0.017	0.016	EPSD	CCLE	0.010	Down-regulation
Other_Aur_AurB_ST	Q9H0H5	RACGAP1	Q96GD4	AURKB	S387	R385M	385	Missense	proximal	-2	no	0.076	0.005	PhosphoSitePlus;EPSD	CCLE	0.010	Loss
Other_Aur_AurB_ST	Q9H0H5	RACGAP1	Q96GD4	AURKB	S600	R599H	599	Missense	proximal	-1	no	0.010	0.002	EPSD	CCLE	0.010	Loss
Other_Aur_AurB_ST	Q9H0H5	RACGAP1	Q96GD4	AURKB	T601	R599H	599	Missense	proximal	-2	no	0.070	-0.001	EPSD	CCLE	0.010	Loss
Other_Aur_AurB_ST	Q12888	TP53BP1	Q96GD4	AURKB	S259	M262R	262	Missense	distal	3	no	0.010	0.009	EPSD	CCLE	0.010	Loss
Other_Aur_AurB_ST	Q12888	TP53BP1	Q96GD4	AURKB	S782	S782L	782	Missense	central	0	yes	0.012	0.000	EPSD	CCLE	0.010	Loss
Other_Aur_AurB_ST	Q12888	TP53BP1	Q96GD4	AURKB	T1270	T1270I	1270	Missense	central	0	yes	0.016	0.000	EPSD	CCLE	0.010	Loss
Other_Aur_AurB_ST	Q12888	TP53BP1	Q96GD4	AURKB	T1370	S1368R	1368	Missense	proximal	-2	no	-0.004	0.069	EPSD	CCLE	0.010	Gain
Other_Aur_AurB_ST	Q12888	TP53BP1	Q96GD4	AURKB	T1654	R1658C	1658	Missense	distal	4	no	0.014	0.013	EPSD	CCLE	0.010	Down-regulation
Other_Aur_AurB_ST	Q12888	TP53BP1	Q96GD4	AURKB	S1660	R1658C	1658	Missense	proximal	-2	no	0.069	-0.001	EPSD	CCLE	0.010	Loss
Other_Aur_AurB_ST	Q13761	RUNX3	Q96GD4	AURKB	S71	T69P	69	Missense	proximal	-2	no	0.012	0.005	EPSD	CCLE	0.010	Loss
Other_Aur_AurB_ST	O00571	DDX3X	Q96GD4	AURKB	S82	S86R	86	Missense	distal	4	no	0.010	0.011	EPSD	CCLE	0.010	Up-regulation
Other_Aur_AurB_ST	O00571	DDX3X	Q96GD4	AURKB	S83	S86R	86	Missense	distal	3	no	0.012	0.011	EPSD	CCLE	0.010	Down-regulation
Other_Aur_AurB_ST	O00571	DDX3X	Q96GD4	AURKB	S90	S86R	86	Missense	distal	-4	no	0.066	0.067	EPSD	CCLE	0.010	Up-regulation
Other_Aur_AurB_ST	P35659	DEK	Q96GD4	AURKB	S204	R208W	208	Missense	distal	4	no	0.016	0.015	EPSD	CCLE	0.010	Down-regulation
Other_Aur_AurB_ST	P35659	DEK	Q96GD4	AURKB	S210	R208W	208	Missense	proximal	-2	no	0.068	-0.001	EPSD	CCLE	0.010	Loss
Other_Aur_AurB_ST	Q9BQG0	MYBBP1A	Q96GD4	AURKB	S635	P632A	632	Missense	distal	-3	no	0.076	0.077	EPSD	CCLE	0.010	Up-regulation
Other_Aur_AurB_ST	Q9BQG0	MYBBP1A	Q96GD4	AURKB	T637	P632A	632	Missense	distal	-5	no	0.011	0.012	EPSD	CCLE	0.010	Up-regulation
Other_Aur_AurB_ST	Q9BQG0	MYBBP1A	Q96GD4	AURKB	S859	S859G	859	Missense	central	0	yes	0.078	0.000	EPSD	CCLE	0.010	Loss
Other_Aur_AurB_ST	Q9BQG0	MYBBP1A	Q96GD4	AURKB	S859	R858H	858	Missense	proximal	-1	no	0.078	0.071	EPSD	CCLE	0.010	Down-regulation
Other_Aur_AurB_ST	Q9BQG0	MYBBP1A	Q96GD4	AURKB	S862	S859G	859	Missense	distal	-3	no	0.010	0.009	EPSD	CCLE	0.010	Loss
Other_Aur_AurB_ST	Q9BQG0	MYBBP1A	Q96GD4	AURKB	S862	R858H	858	Missense	distal	-4	no	0.010	0.009	EPSD	CCLE	0.010	Loss
Other_Aur_AurB_ST	Q9BQG0	MYBBP1A	Q96GD4	AURKB	S863	R858H	858	Missense	distal	-5	no	0.072	0.070	EPSD	CCLE	0.010	Down-regulation
Other_Aur_AurB_ST	Q9H410	DSN1	Q96GD4	AURKB	S49	G47R	47	Missense	proximal	-2	no	-0.004	0.068	EPSD	CCLE	0.010	Gain
Other_Aur_AurB_ST	Q53SF7	COBLL1	Q96GD4	AURKB	T177	P176H	176	Missense	proximal	-1	no	0.010	0.011	EPSD	CCLE	0.010	Up-regulation
Other_Aur_AurB_ST	Q53SF7	COBLL1	Q96GD4	AURKB	T909	R907T	907	Missense	proximal	-2	no	0.068	0.000	EPSD	CCLE	0.010	Loss
Other_Aur_AurB_ST	Q53SF7	COBLL1	Q96GD4	AURKB	S952	S958P	958	Missense	distal	6	no	0.072	0.071	EPSD	CCLE	0.010	Down-regulation
Other_Aur_AurB_ST	Q8NEY8	PPHLN1	Q96GD4	AURKB	S121	R120W	120	Missense	proximal	-1	no	0.012	0.005	EPSD	CCLE	0.010	Loss
Other_Aur_AurB_ST	Q8NEY8	PPHLN1	Q96GD4	AURKB	T396	R400C	400	Missense	distal	4	no	0.076	0.075	EPSD	CCLE	0.010	Down-regulation
Other_Aur_AurB_ST	Q8NEY8	PPHLN1	Q96GD4	AURKB	T403	R400C	400	Missense	distal	-3	no	0.076	0.070	EPSD	CCLE	0.010	Down-regulation
Other_Aur_AurB_ST	Q08J23	NSUN2	Q96GD4	AURKB	S233	L231S	231	Missense	proximal	-2	no	0.010	0.008	EPSD	CCLE	0.010	Loss
Other_Aur_AurB_ST	Q08J23	NSUN2	Q96GD4	AURKB	S233	P234R	234	Missense	proximal	1	no	0.010	0.009	EPSD	CCLE	0.010	Loss
Other_Aur_AurB_ST	P25490	YY1	Q96GD4	AURKB	S365	R363C	363	Missense	proximal	-2	no	0.073	0.002	EPSD	CCLE	0.010	Loss
Other_Aur_AurB_ST	Q8TEW0	PARD3	Q96GD4	AURKB	S873	K870R	870	Missense	distal	-3	no	0.004	0.010	EPSD	CCLE	0.010	Gain
Other_Aur_AurB_ST	P53350	PLK1	Q96GD4	AURKB	S326	F325V	325	Missense	proximal	-1	no	0.072	0.071	EPSD	CCLE	0.010	Down-regulation
Other_Aur_AurB_ST	P18615	NELFE	Q96GD4	AURKB	S39	S37R	37	Missense	proximal	-2	no	-0.003	0.070	EPSD	CCLE	0.010	Gain
Other_Aur_AurB_ST	P18615	NELFE	Q96GD4	AURKB	S131	S131F	131	Missense	central	0	yes	0.078	0.000	PhosphoSitePlus	CCLE	0.010	Loss
Other_Aur_AurB_ST	P18615	NELFE	Q96GD4	AURKB	S131	R126C	126	Missense	distal	-5	no	0.078	0.077	PhosphoSitePlus	CCLE	0.010	Down-regulation
Other_Aur_AurB_ST	P18615	NELFE	Q96GD4	AURKB	S249	R255L	255	Missense	distal	6	no	0.075	0.074	EPSD	CCLE	0.010	Down-regulation
Other_Aur_AurB_ST	Q02241	KIF23	Q96GD4	AURKB	S814	S814C	814	Missense	central	0	yes	0.014	0.000	EPSD	CCLE	0.010	Loss
Other_Aur_AurB_ST	O95235	KIF20A	Q96GD4	AURKB	T328	R326K	326	Missense	proximal	-2	no	0.069	0.011	EPSD	CCLE	0.010	Down-regulation
Other_Aur_AurB_ST	O95235	KIF20A	Q96GD4	AURKB	S478	R475Q	475	Missense	distal	-3	no	0.011	0.005	EPSD	CCLE	0.010	Loss
Other_Aur_AurB_ST	Q8WWK9	CKAP2	Q96GD4	AURKB	T363	R356T	356	Missense	distal	-7	no	0.010	0.011	EPSD	CCLE	0.010	Up-regulation
Other_Aur_AurB_ST	Q9H6F5	CCDC86	Q96GD4	AURKB	T344	R342Q	342	Missense	proximal	-2	no	0.068	-0.006	EPSD	CCLE	0.010	Loss
Other_Aur_AurB_ST	P06748	NPM1	Q96GD4	AURKB	S143	K141R	141	Missense	proximal	-2	no	0.020	0.079	EPSD	CCLE	0.010	Up-regulation
Other_Aur_AurB_ST	Q5T5U3	ARHGAP21	Q96GD4	AURKB	S572	R570S	570	Missense	proximal	-2	no	0.076	0.003	EPSD	CCLE	0.010	Loss
Other_Aur_AurB_ST	Q8IVT2	MISP	Q96GD4	AURKB	S376	R374L	374	Missense	proximal	-2	no	0.074	0.003	EPSD	CCLE	0.010	Loss
Other_Aur_AurB_ST	Q9P227	ARHGAP23	Q96GD4	AURKB	S351	R350C	350	Missense	proximal	-1	no	0.012	0.005	EPSD	CCLE	0.010	Loss
Other_Aur_AurB_ST	Q9P227	ARHGAP23	Q96GD4	AURKB	S361	E363K	363	Missense	proximal	2	no	0.011	0.012	EPSD	CCLE	0.010	Up-regulation
Other_Aur_AurB_ST	Q9P227	ARHGAP23	Q96GD4	AURKB	S610	R609H	609	Missense	proximal	-1	no	0.079	0.072	EPSD	CCLE	0.010	Down-regulation
Other_Aur_AurB_ST	Q9P227	ARHGAP23	Q96GD4	AURKB	S611	R609H	609	Missense	proximal	-2	no	0.078	0.008	EPSD	CCLE	0.010	Loss
Other_Aur_AurB_ST	Q9P227	ARHGAP23	Q96GD4	AURKB	S726	S726L	726	Missense	central	0	yes	0.015	0.000	EPSD	CCLE	0.010	Loss
Other_Aur_AurB_ST	Q9P227	ARHGAP23	Q96GD4	AURKB	S1245	T1243K	1243	Missense	proximal	-2	no	0.011	0.020	EPSD	CCLE	0.010	Up-regulation
Other_Aur_AurB_ST	Q9P227	ARHGAP23	Q96GD4	AURKB	S1245	R1244H	1244	Missense	proximal	-1	no	0.011	0.004	EPSD	CCLE	0.010	Loss
Other_Aur_AurB_ST	Q9P227	ARHGAP23	Q96GD4	AURKB	T1379	L1374R	1374	Missense	distal	-5	no	0.067	0.069	EPSD	CCLE	0.010	Up-regulation
Other_Aur_AurB_ST	Q9P227	ARHGAP23	Q96GD4	AURKB	S1473	G1472R	1472	Missense	proximal	-1	no	0.003	0.011	EPSD	CCLE	0.010	Gain
Other_Aur_AurB_ST	Q9P227	ARHGAP23	Q96GD4	AURKB	S1482	R1480C	1480	Missense	proximal	-2	no	0.079	0.008	EPSD	CCLE	0.010	Loss
Other_Aur_AurB_ST	Q9P227	ARHGAP23	Q96GD4	AURKB	S1482	S1482L	1482	Missense	central	0	yes	0.079	0.000	EPSD	CCLE	0.010	Loss
Other_Aur_AurB_ST	Q8WWI1	LMO7	Q96GD4	AURKB	T949	R948Q	948	Missense	proximal	-1	no	0.016	0.008	EPSD	CCLE	0.010	Loss
Other_Aur_AurB_ST	Q8IX03	WWC1	Q96GD4	AURKB	S33	T28R	28	Missense	distal	-5	no	0.009	0.010	EPSD	CCLE	0.010	Gain
Other_Aur_AurB_ST	Q9Y5B9	SUPT16H	Q96GD4	AURKB	S128	K126E	126	Missense	proximal	-2	no	0.010	-0.003	EPSD	CCLE	0.010	Loss
Other_Aur_AurB_ST	Q9Y5B9	SUPT16H	Q96GD4	AURKB	T494	R491W	491	Missense	distal	-3	no	0.073	0.067	PhosphoSitePlus	CCLE	0.010	Down-regulation
Other_Aur_AurB_ST	Q9Y520	PRRC2C	Q96GD4	AURKB	S1013	R1011K	1011	Missense	proximal	-2	no	0.078	0.019	PhosphoSitePlus	CCLE	0.010	Down-regulation
Other_Aur_AurB_ST	Q9Y520	PRRC2C	Q96GD4	AURKB	T2150	T2150I	2150	Missense	central	0	yes	0.066	0.000	EPSD	CCLE	0.010	Loss
Other_Aur_AurB_ST	P46013	MKI67	Q96GD4	AURKB	S648	S648I	648	Missense	central	0	yes	0.079	0.000	EPSD	CCLE	0.010	Loss
Other_Aur_AurB_ST	P46013	MKI67	Q96GD4	AURKB	T1531	T1531A	1531	Missense	central	0	yes	0.026	0.000	EPSD	CCLE	0.010	Loss
Other_Aur_AurB_ST	P46013	MKI67	Q96GD4	AURKB	S1533	S1533L	1533	Missense	central	0	yes	0.011	0.000	EPSD	CCLE	0.010	Loss
Other_Aur_AurB_ST	P46013	MKI67	Q96GD4	AURKB	S1533	T1531A	1531	Missense	proximal	-2	no	0.011	0.010	EPSD	CCLE	0.010	Down-regulation
Other_Aur_AurB_ST	P46013	MKI67	Q96GD4	AURKB	T2259	R2258P	2258	Missense	proximal	-1	no	0.026	0.018	EPSD	CCLE	0.010	Down-regulation
Other_Aur_AurB_ST	P46013	MKI67	Q96GD4	AURKB	S2261	R2258P	2258	Missense	distal	-3	no	0.011	0.004	EPSD	CCLE	0.010	Loss
Other_Aur_AurB_ST	P46013	MKI67	Q96GD4	AURKB	S2695	Q2693R	2693	Missense	proximal	-2	no	-0.005	0.069	EPSD	CCLE	0.010	Gain
Other_Aur_AurB_ST	P49450	CENPA	Q96GD4	AURKB	S7	R6W	6	Missense	proximal	-1	no	0.082	0.074	PhosphoSitePlus	CCLE	0.010	Down-regulation
Other_Aur_AurB_ST	Q9BW61	DDA1	Q96GD4	AURKB	S95	A91T	91	Missense	distal	-4	no	0.010	0.009	EPSD	CCLE	0.010	Loss
Other_Aur_AurB_ST	O00566	MPHOSPH10	Q96GD4	AURKB	T22	C27R	27	Missense	distal	5	no	0.011	0.009	EPSD	CCLE	0.010	Loss
Other_Aur_AurB_ST	O00566	MPHOSPH10	Q96GD4	AURKB	S468	K466T	466	Missense	proximal	-2	no	0.014	0.005	EPSD	CCLE	0.010	Loss
Other_Aur_AurB_ST	Q9NQZ2	UTP3	Q96GD4	AURKB	S319	Q316R	316	Missense	distal	-3	no	0.012	0.019	EPSD	CCLE	0.010	Up-regulation
Other_Aur_AurB_ST	Q9UQL6	HDAC5	Q96GD4	AURKB	S24	S24P	24	Missense	central	0	yes	0.072	0.000	EPSD	CCLE	0.010	Loss
Other_Aur_AurB_ST	Q15149	PLEC	Q96GD4	AURKB	S1181	R1179Q	1179	Missense	proximal	-2	no	0.070	-0.004	EPSD	CCLE	0.010	Loss
Other_Aur_AurB_ST	Q15149	PLEC	Q96GD4	AURKB	S1181	A1178P	1178	Missense	distal	-3	no	0.070	0.069	EPSD	CCLE	0.010	Down-regulation
Other_Aur_AurB_ST	Q15149	PLEC	Q96GD4	AURKB	S1565	Q1560R	1560	Missense	distal	-5	no	0.068	0.070	EPSD	CCLE	0.010	Up-regulation
Other_Aur_AurB_ST	Q15149	PLEC	Q96GD4	AURKB	T4267	R4265Q	4265	Missense	proximal	-2	no	0.071	-0.003	EPSD	CCLE	0.010	Loss
Other_Aur_AurB_ST	Q15149	PLEC	Q96GD4	AURKB	S4268	R4265Q	4265	Missense	distal	-3	no	0.017	0.010	EPSD	CCLE	0.010	Down-regulation
Other_Aur_AurB_ST	Q15149	PLEC	Q96GD4	AURKB	S4272	R4276H	4276	Missense	distal	4	no	0.010	0.009	EPSD	CCLE	0.010	Loss
Other_Aur_AurB_ST	Q15149	PLEC	Q96GD4	AURKB	S4336	R4334C	4334	Missense	proximal	-2	no	0.079	0.008	EPSD	CCLE	0.010	Loss
Other_Aur_AurB_ST	Q15149	PLEC	Q96GD4	AURKB	S4638	R4635W	4635	Missense	distal	-3	no	0.010	0.004	EPSD	CCLE	0.010	Loss
Other_Aur_AurB_ST	Q15149	PLEC	Q96GD4	AURKB	S4642	A4645T	4645	Missense	distal	3	no	0.076	0.077	EPSD	CCLE	0.010	Up-regulation
Other_Aur_AurB_ST	Q15149	PLEC	Q96GD4	AURKB	S4642	G4637S	4637	Missense	distal	-5	no	0.076	0.077	EPSD	CCLE	0.010	Up-regulation
Other_Aur_AurB_ST	Q15149	PLEC	Q96GD4	AURKB	S4642	R4635W	4635	Missense	distal	-7	no	0.076	0.077	EPSD	CCLE	0.010	Up-regulation
Other_Aur_AurB_ST	Q96E39	RBMXL1	Q96GD4	AURKB	T231	R229H	229	Missense	proximal	-2	no	0.065	-0.006	EPSD	CCLE	0.010	Loss
Other_Aur_AurB_ST	Q09666	AHNAK	Q96GD4	AURKB	S2775	P2772L	2772	Missense	distal	-3	no	0.010	0.011	EPSD	CCLE	0.010	Up-regulation
Other_Aur_AurB_ST	Q09666	AHNAK	Q96GD4	AURKB	S3483	P3480S	3480	Missense	distal	-3	no	0.010	0.011	EPSD	CCLE	0.010	Up-regulation
Other_Aur_AurB_ST	O76021	RSL1D1	Q96GD4	AURKB	S474	K479E	479	Missense	distal	5	no	0.019	0.020	EPSD	CCLE	0.010	Up-regulation
Other_NEK_NEK2_NEK2_ST	Q8N137	CNTROB	P51955	NEK2	T570	N576S	576	Missense	distal	6	no	1.684	1.610	EPSD	CCLE	1.575	Down-regulation
Other_NEK_NEK2_NEK2_ST	Q8N137	CNTROB	P51955	NEK2	T571	N576S	576	Missense	distal	5	no	1.685	1.687	EPSD	CCLE	1.575	Up-regulation
Other_NEK_NEK2_NEK2_ST	Q9H2D6	TRIOBP	P51955	NEK2	S895	N891D	891	Missense	distal	-4	no	1.687	1.650	EPSD	CCLE	1.575	Down-regulation
Other_NEK_NEK2_NEK2_ST	Q9H2D6	TRIOBP	P51955	NEK2	T1993	R1987C	1987	Missense	distal	-6	no	3.137	3.138	EPSD	CCLE	1.575	Up-regulation
Other_NEK_NEK2_NEK2_ST	Q92997	DVL3	P51955	NEK2	S643	S636G	636	Missense	distal	-7	no	2.943	2.488	EPSD;PhosphoSitePlus	CCLE	1.575	Down-regulation
Other_NEK_NEK2_NEK2_ST	P06748	NPM1	P51955	NEK2	S139	K141R	141	Missense	proximal	2	no	1.497	1.588	EPSD	CCLE	1.575	Gain
Other_NEK_NEK2_NEK2_ST	P06748	NPM1	P51955	NEK2	S143	K141R	141	Missense	proximal	-2	no	1.686	1.854	EPSD	CCLE	1.575	Up-regulation
Other_NEK_NEK2_NEK2_ST	P13639	EEF2	P51955	NEK2	T59	R60Q	60	Missense	proximal	1	no	2.168	2.103	EPSD	CCLE	1.575	Down-regulation
Other_NEK_NEK2_NEK2_ST	P13639	EEF2	P51955	NEK2	S360	P361H	361	Missense	proximal	1	no	1.679	1.638	EPSD	CCLE	1.575	Down-regulation
Other_NEK_NEK2_NEK2_ST	P13639	EEF2	P51955	NEK2	S595	C591Y	591	Missense	distal	-4	no	2.095	2.089	PhosphoSitePlus	CCLE	1.575	Down-regulation
Other_NEK_NEK2_NEK2_ST	P13639	EEF2	P51955	NEK2	S732	R739H	739	Missense	distal	7	no	1.725	1.762	EPSD	CCLE	1.575	Up-regulation
Other_NEK_NEK2_NEK2_ST	O14777	NDC80	P51955	NEK2	S165	S167R	167	Missense	proximal	2	no	4.351	4.408	PhosphoSitePlus	CCLE	1.575	Up-regulation
Other_NEK_NEK2_NEK2_ST	P04637	TP53	P51955	NEK2	S106	G108V	108	Missense	proximal	2	no	1.544	1.589	EPSD	CCLE	1.575	Gain
CAMK_PIM_PIM1_ST	Q99683	MAP3K5	P11309	PIM1	S83	R78Q	78	Missense	distal	-5	no	0.002	0.001	PhosphoSitePlus	CCLE	0.001	Down-regulation
CAMK_PIM_PIM1_ST	Q92934	BAD	P11309	PIM1	S75	R70W	70	Missense	distal	-5	no	0.002	0.001	PhosphoSitePlus	CCLE	0.001	Down-regulation
CAMK_PIM_PIM1_ST	P27448	MARK3	P11309	PIM1	T602	T602A	602	Missense	central	0	yes	0.002	0.000	EPSD	CCLE	0.001	Loss
CAMK_PIM_PIM1_ST	P27448	MARK3	P11309	PIM1	S737	R732W	732	Missense	distal	-5	no	0.001	0.000	EPSD	CCLE	0.001	Loss
CAMK_PIM_PIM1_ST	Q13761	RUNX3	P11309	PIM1	T209	L204P	204	Missense	distal	-5	no	0.001	0.000	EPSD	CCLE	0.001	Loss
CAMK_PIM_PIM1_ST	Q13761	RUNX3	P11309	PIM1	T221	T221P	221	Missense	central	0	yes	0.001	0.000	EPSD	CCLE	0.001	Loss
CAMK_PIM_PIM1_ST	Q13761	RUNX3	P11309	PIM1	S385	S380R	380	Missense	distal	-5	no	0.000	0.001	EPSD	CCLE	0.001	Gain
CAMK_PIM_PIM1_ST	P35568	IRS1	P11309	PIM1	S24	L19R	19	Missense	distal	-5	no	0.001	0.002	EPSD	CCLE	0.001	Up-regulation
CAMK_PIM_PIM1_ST	P35568	IRS1	P11309	PIM1	T305	R302Q	302	Missense	distal	-3	no	0.001	0.000	EPSD	CCLE	0.001	Loss
CAMK_PIM_PIM1_ST	P35568	IRS1	P11309	PIM1	S307	R304H	304	Missense	distal	-3	no	0.002	0.001	EPSD	CCLE	0.001	Down-regulation
CAMK_PIM_PIM1_ST	P35568	IRS1	P11309	PIM1	S307	R302Q	302	Missense	distal	-5	no	0.002	0.001	EPSD	CCLE	0.001	Down-regulation
CAMK_PIM_PIM1_ST	P35568	IRS1	P11309	PIM1	T309	R304H	304	Missense	distal	-5	no	0.001	0.000	EPSD	CCLE	0.001	Loss
CAMK_PIM_PIM1_ST	P35568	IRS1	P11309	PIM1	S795	S795Y	795	Missense	central	0	yes	0.001	0.000	EPSD	CCLE	0.001	Loss
CAMK_PIM_PIM1_ST	O43524	FOXO3	P11309	PIM1	S30	R27G	27	Missense	distal	-3	no	0.001	0.000	EPSD	CCLE	0.001	Loss
CAMK_PIM_PIM1_ST	O43524	FOXO3	P11309	PIM1	T32	R27G	27	Missense	distal	-5	no	0.002	0.001	PhosphoSitePlus;EPSD	CCLE	0.001	Down-regulation
CAMK_PIM_PIM1_ST	Q9Y4H2	IRS2	P11309	PIM1	T404	T404I	404	Missense	central	0	yes	0.001	0.000	EPSD	CCLE	0.001	Loss
CAMK_PIM_PIM1_ST	Q9Y4H2	IRS2	P11309	PIM1	T891	R886Q	886	Missense	distal	-5	no	0.002	0.000	EPSD	CCLE	0.001	Loss
CAMK_PIM_PIM1_ST	Q9BZS1	FOXP3	P11309	PIM1	S422	R417Q	417	Missense	distal	-5	no	0.002	0.001	PhosphoSitePlus	CCLE	0.001	Down-regulation
STE_STE20_MST_STK4_ST	Q14457	BECN1	Q13043	STK4	S64	P68S	68	Missense	distal	4	no	4.912	4.945	EPSD	CCLE	4.850	Up-regulation
STE_STE20_MST_STK4_ST	Q14457	BECN1	Q13043	STK4	T72	P68S	68	Missense	distal	-4	no	4.913	4.912	EPSD	CCLE	4.850	Down-regulation
STE_STE20_MST_STK4_ST	Q14457	BECN1	Q13043	STK4	T91	S93N	93	Missense	proximal	2	no	4.851	4.872	EPSD	CCLE	4.850	Up-regulation
STE_STE20_MST_STK4_ST	Q06830	PRDX1	Q13043	STK4	T18	V20G	20	Missense	proximal	2	no	4.889	4.853	EPSD;PhosphoSitePlus	CCLE	4.850	Down-regulation
STE_STE20_MST_STK4_ST	P19429	TNNI3	Q13043	STK4	T119	I114T	114	Missense	distal	-5	no	4.840	4.864	EPSD	CCLE	4.850	Gain
STE_STE20_MST_STK4_ST	Q13043	STK4	Q13043	STK4	S422	N421K	421	Missense	proximal	-1	no	4.854	4.853	EPSD	CCLE	4.850	Down-regulation
STE_STE20_MST_STK4_ST	P00519	ABL1	Q13043	STK4	S859	T865P	865	Missense	distal	6	no	4.920	4.908	EPSD	CCLE	4.850	Down-regulation
STE_STE20_MST_STK4_ST	Q96GD4	AURKB	Q13043	STK4	S22	L24V	24	Missense	proximal	2	no	4.841	4.860	EPSD	CCLE	4.850	Gain
STE_STE20_KHS_MAP4K3_ST	Q04759	PRKCQ	Q8IVH8	MAP4K3	S297	M294L	294	Missense	distal	-3	no	3.094	3.099	EPSD	CCLE	2.839	Up-regulation
STE_STE20_KHS_MAP4K3_ST	P19484	TFEB	Q8IVH8	MAP4K3	S332	G335S	335	Missense	distal	3	no	3.655	0.577	EPSD	CCLE	2.839	Loss
TK_Eph_EPHA4_Y	P54764	EPHA4	P54764	EPHA4	Y596	E603Q	603	Missense	distal	7	no	4.449	4.488	EPSD;PhosphoSitePlus	CCLE	1.226	Up-regulation
TK_Eph_EPHA4_Y	P54764	EPHA4	P54764	EPHA4	Y602	E603Q	603	Missense	proximal	1	no	4.080	4.155	PhosphoSitePlus;EPSD	CCLE	1.226	Up-regulation
CMGC_MAPK_ERK3_MAPK6_ST	Q9Y6Q9	NCOA3	Q16659	MAPK6	T773	E780Q	780	Missense	distal	7	no	2.240	2.232	EPSD	CCLE	2.026	Down-regulation
CAMK_CAMK2_CAMK2G_ST	Q13555	CAMK2G	Q13555	CAMK2G	S280	R284C	284	Missense	distal	4	no	6.076	6.026	EPSD;PhosphoSitePlus	CCLE	2.962	Down-regulation
CAMK_CAMK2_CAMK2G_ST	Q13555	CAMK2G	Q13555	CAMK2G	T287	R284C	284	Missense	distal	-3	no	6.560	5.032	EPSD	CCLE	2.962	Down-regulation
CAMK_CAMK2_CAMK2G_ST	Q13555	CAMK2G	Q13555	CAMK2G	S423	L420P	420	Missense	distal	-3	no	3.576	2.420	EPSD	CCLE	2.962	Loss
CAMK_CAMK2_CAMK2G_ST	O95180	CACNA1H	Q13555	CAMK2G	S475	R477H	477	Missense	proximal	2	no	3.189	3.235	EPSD	CCLE	2.962	Up-regulation
CAMK_CAMK2_CAMK2G_ST	O95180	CACNA1H	Q13555	CAMK2G	S484	R477H	477	Missense	distal	-7	no	3.793	3.107	EPSD	CCLE	2.962	Down-regulation
CAMK_CAMK2_CAMK2G_ST	O95180	CACNA1H	Q13555	CAMK2G	S484	R485C	485	Missense	proximal	1	no	3.793	3.693	EPSD	CCLE	2.962	Down-regulation
CAMK_CAMK2_CAMK2G_ST	O95180	CACNA1H	Q13555	CAMK2G	S558	P557L	557	Missense	proximal	-1	no	3.040	2.896	EPSD	CCLE	2.962	Loss
CAMK_CAMK2_CAMK2G_ST	O95180	CACNA1H	Q13555	CAMK2G	S558	R564C	564	Missense	distal	6	no	3.040	2.545	EPSD	CCLE	2.962	Loss
CAMK_CAMK2_CAMK2G_ST	O95180	CACNA1H	Q13555	CAMK2G	S1091	P1088L	1088	Missense	distal	-3	no	1.977	3.133	EPSD	CCLE	2.962	Gain
CAMK_CAMK2_CAMK2G_ST	O95180	CACNA1H	Q13555	CAMK2G	S1168	R1163C	1163	Missense	distal	-5	no	3.279	3.591	EPSD	CCLE	2.962	Up-regulation
CAMK_CAMK2_CAMK2G_ST	O95180	CACNA1H	Q13555	CAMK2G	S1168	E1164G	1164	Missense	distal	-4	no	3.279	3.330	EPSD	CCLE	2.962	Up-regulation
CAMK_CAMK2_CAMK2G_ST	O95180	CACNA1H	Q13555	CAMK2G	S1168	E1170K	1170	Missense	proximal	2	no	3.279	3.258	EPSD	CCLE	2.962	Down-regulation
CAMK_CAMK2_CAMK2G_ST	O95180	CACNA1H	Q13555	CAMK2G	T1175	E1170K	1170	Missense	distal	-5	no	3.089	2.976	EPSD	CCLE	2.962	Down-regulation
Atypical_PDHK_PDHK_PDK1_ST	P08559	PDHA1	Q15118	PDK1	S232	A236V	236	Missense	distal	4	no	0.299	0.273	EPSD;PhosphoSitePlus	CCLE	0.124	Down-regulation
Atypical_PDHK_PDHK_PDK1_ST	P29803	PDHA2	Q15118	PDK1	S230	G228E	228	Missense	proximal	-2	no	0.332	0.328	EPSD;PhosphoSitePlus	CCLE	0.124	Down-regulation
Atypical_PDHK_PDHK_PDK1_ST	P29803	PDHA2	Q15118	PDK1	S291	H288Y	288	Missense	distal	-3	no	0.357	0.363	EPSD;PhosphoSitePlus	CCLE	0.124	Up-regulation
Atypical_PDHK_PDHK_PDK1_ST	P29803	PDHA2	Q15118	PDK1	S291	H288R	288	Missense	distal	-3	no	0.357	0.365	EPSD;PhosphoSitePlus	CCLE	0.124	Up-regulation
Atypical_PDHK_PDHK_PDK1_ST	P29803	PDHA2	Q15118	PDK1	S293	H288R	288	Missense	distal	-5	no	0.147	0.151	EPSD	CCLE	0.124	Up-regulation
CMGC_MAPK_JNK_MAPK8_ST	Q96EB6	SIRT1	P45983	MAPK8	S27	A29T	29	Missense	proximal	2	no	10.271	10.250	EPSD;PhosphoSitePlus	CCLE	2.638	Down-regulation
CMGC_MAPK_JNK_MAPK8_ST	Q96EB6	SIRT1	P45983	MAPK8	S47	G52V	52	Missense	distal	5	no	6.651	6.664	PhosphoSitePlus;EPSD	CCLE	2.638	Up-regulation
CMGC_MAPK_JNK_MAPK8_ST	Q96EB6	SIRT1	P45983	MAPK8	S659	E662D	662	Missense	distal	3	no	2.712	2.820	EPSD	CCLE	2.638	Up-regulation
CMGC_MAPK_JNK_MAPK8_ST	P36956	SREBF1	P45983	MAPK8	S63	P69T	69	Missense	distal	6	no	9.118	9.139	EPSD	CCLE	2.638	Up-regulation
CMGC_MAPK_JNK_MAPK8_ST	P36956	SREBF1	P45983	MAPK8	S63	A62V	62	Missense	proximal	-1	no	9.118	9.082	EPSD	CCLE	2.638	Down-regulation
CMGC_MAPK_JNK_MAPK8_ST	P36956	SREBF1	P45983	MAPK8	T105	K108Q	108	Missense	distal	3	no	5.927	6.024	EPSD	CCLE	2.638	Up-regulation
CMGC_MAPK_JNK_MAPK8_ST	P36956	SREBF1	P45983	MAPK8	S112	K108Q	108	Missense	distal	-4	no	2.866	2.473	EPSD	CCLE	2.638	Loss
CMGC_MAPK_JNK_MAPK8_ST	P36956	SREBF1	P45983	MAPK8	T426	E422D	422	Missense	distal	-4	no	8.292	7.869	EPSD	CCLE	2.638	Down-regulation
CMGC_MAPK_JNK_MAPK8_ST	P36956	SREBF1	P45983	MAPK8	S524	S520G	520	Missense	distal	-4	no	7.341	6.452	EPSD	CCLE	2.638	Down-regulation
CMGC_MAPK_JNK_MAPK8_ST	P10636	MAPT	P45983	MAPK8	T69	A66V	66	Missense	distal	-3	no	8.525	8.096	EPSD	CCLE	2.638	Down-regulation
CMGC_MAPK_JNK_MAPK8_ST	P10636	MAPT	P45983	MAPK8	T111	G107V	107	Missense	distal	-4	no	7.410	7.266	EPSD	CCLE	2.638	Down-regulation
CMGC_MAPK_JNK_MAPK8_ST	P10636	MAPT	P45983	MAPK8	S228	D221Y	221	Missense	distal	-7	no	9.293	9.306	EPSD	CCLE	2.638	Up-regulation
CMGC_MAPK_JNK_MAPK8_ST	P10636	MAPT	P45983	MAPK8	S228	P234S	234	Missense	distal	6	no	9.293	9.317	EPSD	CCLE	2.638	Up-regulation
CMGC_MAPK_JNK_MAPK8_ST	P10636	MAPT	P45983	MAPK8	S232	P234S	234	Missense	proximal	2	no	7.907	8.092	EPSD	CCLE	2.638	Up-regulation
CMGC_MAPK_JNK_MAPK8_ST	P10636	MAPT	P45983	MAPK8	S238	P234S	234	Missense	distal	-4	no	7.548	8.213	EPSD	CCLE	2.638	Up-regulation
CMGC_MAPK_JNK_MAPK8_ST	P10636	MAPT	P45983	MAPK8	S238	D242H	242	Missense	distal	4	no	7.548	7.422	EPSD	CCLE	2.638	Down-regulation
CMGC_MAPK_JNK_MAPK8_ST	P10636	MAPT	P45983	MAPK8	S400	K405R	405	Missense	distal	5	no	3.493	3.584	EPSD	CCLE	2.638	Up-regulation
CMGC_MAPK_JNK_MAPK8_ST	P10636	MAPT	P45983	MAPK8	S411	K405R	405	Missense	distal	-6	no	7.541	7.707	EPSD	CCLE	2.638	Up-regulation
CMGC_MAPK_JNK_MAPK8_ST	P10636	MAPT	P45983	MAPK8	S438	V442I	442	Missense	distal	4	no	9.810	10.140	EPSD	CCLE	2.638	Up-regulation
CMGC_MAPK_JNK_MAPK8_ST	P10636	MAPT	P45983	MAPK8	S447	V442I	442	Missense	distal	-5	no	3.231	2.911	EPSD	CCLE	2.638	Down-regulation
CMGC_MAPK_JNK_MAPK8_ST	P10636	MAPT	P45983	MAPK8	S516	R511H	511	Missense	distal	-5	no	8.663	8.567	EPSD	CCLE	2.638	Down-regulation
CMGC_MAPK_JNK_MAPK8_ST	P10636	MAPT	P45983	MAPK8	S516	G518S	518	Missense	proximal	2	no	8.663	8.865	EPSD	CCLE	2.638	Up-regulation
CMGC_MAPK_JNK_MAPK8_ST	P10636	MAPT	P45983	MAPK8	S519	G518S	518	Missense	proximal	-1	no	8.616	8.640	EPSD	CCLE	2.638	Up-regulation
CMGC_MAPK_JNK_MAPK8_ST	P10636	MAPT	P45983	MAPK8	S519	R526L	526	Missense	distal	7	no	8.616	8.631	EPSD	CCLE	2.638	Up-regulation
CMGC_MAPK_JNK_MAPK8_ST	P10636	MAPT	P45983	MAPK8	T522	G518S	518	Missense	distal	-4	no	5.986	6.875	EPSD	CCLE	2.638	Up-regulation
CMGC_MAPK_JNK_MAPK8_ST	P10636	MAPT	P45983	MAPK8	T522	R526L	526	Missense	distal	4	no	5.986	5.919	EPSD	CCLE	2.638	Down-regulation
CMGC_MAPK_JNK_MAPK8_ST	P10636	MAPT	P45983	MAPK8	T529	R526L	526	Missense	distal	-3	no	8.571	8.534	EPSD	CCLE	2.638	Down-regulation
CMGC_MAPK_JNK_MAPK8_ST	P10636	MAPT	P45983	MAPK8	S552	R559H	559	Missense	distal	7	no	7.655	7.645	EPSD	CCLE	2.638	Down-regulation
CMGC_MAPK_JNK_MAPK8_ST	P10636	MAPT	P45983	MAPK8	S555	R559H	559	Missense	distal	4	no	3.344	3.381	EPSD	CCLE	2.638	Up-regulation
CMGC_MAPK_JNK_MAPK8_ST	P10636	MAPT	P45983	MAPK8	S558	R559H	559	Missense	proximal	1	no	3.924	3.145	EPSD	CCLE	2.638	Down-regulation
CMGC_MAPK_JNK_MAPK8_ST	P10636	MAPT	P45983	MAPK8	T703	G706V	706	Missense	distal	3	no	2.783	2.839	EPSD	CCLE	2.638	Up-regulation
CMGC_MAPK_JNK_MAPK8_ST	P10636	MAPT	P45983	MAPK8	S713	G706V	706	Missense	distal	-7	no	9.699	9.704	EPSD	CCLE	2.638	Up-regulation
CMGC_MAPK_JNK_MAPK8_ST	P10636	MAPT	P45983	MAPK8	S713	S717C	717	Missense	distal	4	no	9.699	9.368	EPSD	CCLE	2.638	Down-regulation
CMGC_MAPK_JNK_MAPK8_ST	P10636	MAPT	P45983	MAPK8	S721	S717C	717	Missense	distal	-4	no	8.703	7.935	EPSD	CCLE	2.638	Down-regulation
CMGC_MAPK_JNK_MAPK8_ST	P10636	MAPT	P45983	MAPK8	S721	S721C	721	Missense	central	0	yes	8.703	0.000	EPSD	CCLE	2.638	Loss
CMGC_MAPK_JNK_MAPK8_ST	P10636	MAPT	P45983	MAPK8	S721	H724R	724	Missense	distal	3	no	8.703	8.722	EPSD	CCLE	2.638	Up-regulation
CMGC_MAPK_JNK_MAPK8_ST	P10636	MAPT	P45983	MAPK8	S739	Q741K	741	Missense	proximal	2	no	7.702	7.850	EPSD	CCLE	2.638	Up-regulation
CMGC_MAPK_JNK_MAPK8_ST	P17275	JUNB	P45983	MAPK8	S74	Y68C	68	Missense	distal	-6	no	2.706	2.604	EPSD	CCLE	2.638	Loss
CMGC_MAPK_JNK_MAPK8_ST	P17275	JUNB	P45983	MAPK8	T102	Y109H	109	Missense	distal	7	no	8.898	8.858	PhosphoSitePlus;EPSD	CCLE	2.638	Down-regulation
CMGC_MAPK_JNK_MAPK8_ST	P17275	JUNB	P45983	MAPK8	T104	Y109H	109	Missense	distal	5	no	8.622	8.565	EPSD;PhosphoSitePlus	CCLE	2.638	Down-regulation
CMGC_MAPK_JNK_MAPK8_ST	P17275	JUNB	P45983	MAPK8	T255	D253N	253	Missense	proximal	-2	no	7.948	7.851	EPSD	CCLE	2.638	Down-regulation
CMGC_MAPK_JNK_MAPK8_ST	P17275	JUNB	P45983	MAPK8	S259	D253N	253	Missense	distal	-6	no	8.416	8.498	EPSD	CCLE	2.638	Up-regulation
CMGC_MAPK_JNK_MAPK8_ST	Q9NRA8	EIF4ENIF1	P45983	MAPK8	S301	D304E	304	Missense	distal	3	no	9.158	9.051	EPSD;PhosphoSitePlus	CCLE	2.638	Down-regulation
CMGC_MAPK_JNK_MAPK8_ST	Q9NRA8	EIF4ENIF1	P45983	MAPK8	T924	V919I	919	Missense	distal	-5	no	8.601	8.280	EPSD	CCLE	2.638	Down-regulation
CMGC_MAPK_JNK_MAPK8_ST	Q9NRA8	EIF4ENIF1	P45983	MAPK8	S951	P945T	945	Missense	distal	-6	no	7.297	7.233	EPSD	CCLE	2.638	Down-regulation
CMGC_MAPK_JNK_MAPK8_ST	Q05639	EEF1A2	P45983	MAPK8	S358	S354G	354	Missense	distal	-4	no	8.216	7.327	PhosphoSitePlus;EPSD	CCLE	2.638	Down-regulation
CMGC_MAPK_JNK_MAPK8_ST	Q9H211	CDT1	P45983	MAPK8	T29	A26P	26	Missense	distal	-3	no	7.974	7.776	PhosphoSitePlus;EPSD	CCLE	2.638	Down-regulation
CMGC_MAPK_JNK_MAPK8_ST	Q9H211	CDT1	P45983	MAPK8	T29	C27F	27	Missense	proximal	-2	no	7.974	7.923	PhosphoSitePlus;EPSD	CCLE	2.638	Down-regulation
CMGC_MAPK_JNK_MAPK8_ST	Q9H211	CDT1	P45983	MAPK8	T29	T29P	29	Missense	central	0	yes	7.974	0.000	PhosphoSitePlus;EPSD	CCLE	2.638	Loss
CMGC_MAPK_JNK_MAPK8_ST	Q9H211	CDT1	P45983	MAPK8	S31	A26P	26	Missense	distal	-5	no	7.719	7.847	EPSD	CCLE	2.638	Up-regulation
CMGC_MAPK_JNK_MAPK8_ST	Q9H211	CDT1	P45983	MAPK8	S31	C27F	27	Missense	distal	-4	no	7.719	7.549	EPSD	CCLE	2.638	Down-regulation
CMGC_MAPK_JNK_MAPK8_ST	Q9H211	CDT1	P45983	MAPK8	S31	T29P	29	Missense	proximal	-2	no	7.719	7.799	EPSD	CCLE	2.638	Up-regulation
CMGC_MAPK_JNK_MAPK8_ST	Q9H211	CDT1	P45983	MAPK8	S45	A43T	43	Missense	proximal	-2	no	2.856	2.827	EPSD	CCLE	2.638	Down-regulation
CMGC_MAPK_JNK_MAPK8_ST	Q9H211	CDT1	P45983	MAPK8	S79	S81N	81	Missense	proximal	2	no	9.355	9.093	EPSD	CCLE	2.638	Down-regulation
CMGC_MAPK_JNK_MAPK8_ST	Q9H211	CDT1	P45983	MAPK8	T82	S81N	81	Missense	proximal	-1	no	8.851	8.823	EPSD	CCLE	2.638	Down-regulation
CMGC_MAPK_JNK_MAPK8_ST	Q9H211	CDT1	P45983	MAPK8	T102	G106D	106	Missense	distal	4	no	7.593	7.735	EPSD	CCLE	2.638	Up-regulation
CMGC_MAPK_JNK_MAPK8_ST	Q9H211	CDT1	P45983	MAPK8	T152	A155V	155	Missense	distal	3	no	7.438	7.665	EPSD	CCLE	2.638	Up-regulation
CMGC_MAPK_JNK_MAPK8_ST	Q9H211	CDT1	P45983	MAPK8	S372	M375I	375	Missense	distal	3	no	8.781	8.700	EPSD	CCLE	2.638	Down-regulation
CMGC_MAPK_JNK_MAPK8_ST	Q9H211	CDT1	P45983	MAPK8	S391	P395S	395	Missense	distal	4	no	7.295	7.320	EPSD;PhosphoSitePlus	CCLE	2.638	Up-regulation
CMGC_MAPK_JNK_MAPK8_ST	Q9H211	CDT1	P45983	MAPK8	S394	P395S	395	Missense	proximal	1	no	9.045	1.316	EPSD	CCLE	2.638	Loss
CMGC_MAPK_JNK_MAPK8_ST	Q9H211	CDT1	P45983	MAPK8	T402	P395S	395	Missense	distal	-7	no	8.894	8.888	EPSD;PhosphoSitePlus	CCLE	2.638	Down-regulation
CMGC_MAPK_JNK_MAPK8_ST	P15336	ATF2	P45983	MAPK8	T69	R74K	74	Missense	distal	5	no	8.052	7.961	PhosphoSitePlus;EPSD	CCLE	2.638	Down-regulation
CMGC_MAPK_JNK_MAPK8_ST	P15336	ATF2	P45983	MAPK8	T71	R74K	74	Missense	distal	3	no	8.758	8.535	EPSD;PhosphoSitePlus	CCLE	2.638	Down-regulation
CMGC_MAPK_JNK_MAPK8_ST	P15336	ATF2	P45983	MAPK8	T325	A330G	330	Missense	distal	5	no	7.959	8.019	EPSD	CCLE	2.638	Up-regulation
CMGC_MAPK_JNK_MAPK8_ST	P15336	ATF2	P45983	MAPK8	T325	A319D	319	Missense	distal	-6	no	7.959	8.049	EPSD	CCLE	2.638	Up-regulation
CMGC_MAPK_JNK_MAPK8_ST	P15336	ATF2	P45983	MAPK8	S328	A330G	330	Missense	proximal	2	no	8.292	8.065	EPSD	CCLE	2.638	Down-regulation
CMGC_MAPK_JNK_MAPK8_ST	P15336	ATF2	P45983	MAPK8	T333	A330G	330	Missense	distal	-3	no	7.887	7.571	EPSD	CCLE	2.638	Down-regulation
CMGC_MAPK_JNK_MAPK8_ST	P01106	MYC	P45983	MAPK8	T58	E54K	54	Missense	distal	-4	no	7.250	7.506	EPSD	CCLE	2.638	Up-regulation
CMGC_MAPK_JNK_MAPK8_ST	P01106	MYC	P45983	MAPK8	T58	P57H	57	Missense	proximal	-1	no	7.250	7.239	EPSD	CCLE	2.638	Down-regulation
CMGC_MAPK_JNK_MAPK8_ST	P01106	MYC	P45983	MAPK8	S62	P57H	57	Missense	distal	-5	no	8.065	8.262	EPSD;PhosphoSitePlus	CCLE	2.638	Up-regulation
CMGC_MAPK_JNK_MAPK8_ST	P01106	MYC	P45983	MAPK8	S62	L69I	69	Missense	distal	7	no	8.065	8.027	EPSD;PhosphoSitePlus	CCLE	2.638	Down-regulation
CMGC_MAPK_JNK_MAPK8_ST	P01106	MYC	P45983	MAPK8	S71	L69I	69	Missense	proximal	-2	no	8.539	8.628	PhosphoSitePlus;EPSD	CCLE	2.638	Up-regulation
CMGC_MAPK_JNK_MAPK8_ST	P01106	MYC	P45983	MAPK8	S71	Y74S	74	Missense	distal	3	no	8.539	8.258	PhosphoSitePlus;EPSD	CCLE	2.638	Down-regulation
CMGC_MAPK_JNK_MAPK8_ST	P01106	MYC	P45983	MAPK8	S71	T78R	78	Missense	distal	7	no	8.539	8.595	PhosphoSitePlus;EPSD	CCLE	2.638	Up-regulation
CMGC_MAPK_JNK_MAPK8_ST	P01106	MYC	P45983	MAPK8	T78	Y74S	74	Missense	distal	-4	no	6.974	8.208	EPSD	CCLE	2.638	Up-regulation
CMGC_MAPK_JNK_MAPK8_ST	P01106	MYC	P45983	MAPK8	T78	T78R	78	Missense	central	0	yes	6.974	0.000	EPSD	CCLE	2.638	Loss
CMGC_MAPK_JNK_MAPK8_ST	P01106	MYC	P45983	MAPK8	T78	L82F	82	Missense	distal	4	no	6.974	6.948	EPSD	CCLE	2.638	Down-regulation
CMGC_MAPK_JNK_MAPK8_ST	P01106	MYC	P45983	MAPK8	S204	K206T	206	Missense	proximal	2	no	8.001	7.923	EPSD	CCLE	2.638	Down-regulation
CMGC_MAPK_JNK_MAPK8_ST	P05067	APP	P45983	MAPK8	T381	E385K	385	Missense	distal	4	no	7.538	7.619	EPSD	CCLE	2.638	Up-regulation
CMGC_MAPK_JNK_MAPK8_ST	P05067	APP	P45983	MAPK8	T743	D739V	739	Missense	distal	-4	no	9.063	8.597	EPSD	CCLE	2.638	Down-regulation
CMGC_MAPK_JNK_MAPK8_ST	O43524	FOXO3	P45983	MAPK8	S43	Q41K	41	Missense	proximal	-2	no	8.792	8.827	EPSD	CCLE	2.638	Up-regulation
CMGC_MAPK_JNK_MAPK8_ST	O43524	FOXO3	P45983	MAPK8	S446	R444C	444	Missense	proximal	-2	no	7.804	7.817	EPSD	CCLE	2.638	Up-regulation
CMGC_MAPK_JNK_MAPK8_ST	O43524	FOXO3	P45983	MAPK8	T450	R444C	444	Missense	distal	-6	no	3.347	3.322	EPSD	CCLE	2.638	Down-regulation
CMGC_MAPK_JNK_MAPK8_ST	P10276	RARA	P45983	MAPK8	S74	P79L	79	Missense	distal	5	no	7.189	7.187	EPSD	CCLE	2.638	Down-regulation
CMGC_MAPK_JNK_MAPK8_ST	P10276	RARA	P45983	MAPK8	S77	P79L	79	Missense	proximal	2	no	7.003	6.926	EPSD	CCLE	2.638	Down-regulation
CMGC_MAPK_JNK_MAPK8_ST	P10276	RARA	P45983	MAPK8	S445	P440L	440	Missense	distal	-5	no	8.338	8.698	EPSD;PhosphoSitePlus	CCLE	2.638	Up-regulation
CMGC_MAPK_JNK_MAPK8_ST	P54259	ATN1	P45983	MAPK8	S43	A47D	47	Missense	distal	4	no	3.082	2.880	EPSD	CCLE	2.638	Down-regulation
CMGC_MAPK_JNK_MAPK8_ST	P54259	ATN1	P45983	MAPK8	T630	P633Q	633	Missense	distal	3	no	2.902	2.833	EPSD	CCLE	2.638	Down-regulation
CMGC_MAPK_JNK_MAPK8_ST	P54259	ATN1	P45983	MAPK8	S632	P633Q	633	Missense	proximal	1	no	8.266	1.157	EPSD	CCLE	2.638	Loss
CMGC_MAPK_JNK_MAPK8_ST	P54259	ATN1	P45983	MAPK8	S645	P644Q	644	Missense	proximal	-1	no	8.385	8.391	EPSD	CCLE	2.638	Up-regulation
CMGC_MAPK_JNK_MAPK8_ST	P54259	ATN1	P45983	MAPK8	S677	P682T	682	Missense	distal	5	no	7.184	7.108	EPSD	CCLE	2.638	Down-regulation
CMGC_MAPK_JNK_MAPK8_ST	P54259	ATN1	P45983	MAPK8	S689	P682T	682	Missense	distal	-7	no	8.420	8.416	EPSD	CCLE	2.638	Down-regulation
CMGC_MAPK_JNK_MAPK8_ST	P54259	ATN1	P45983	MAPK8	S689	G695E	695	Missense	distal	6	no	8.420	8.479	EPSD	CCLE	2.638	Up-regulation
CMGC_MAPK_JNK_MAPK8_ST	P54259	ATN1	P45983	MAPK8	S780	S776W	776	Missense	distal	-4	no	3.794	2.749	EPSD	CCLE	2.638	Down-regulation
CMGC_MAPK_JNK_MAPK8_ST	P22736	NR4A1	P45983	MAPK8	S95	S98F	98	Missense	distal	3	no	8.503	8.722	PhosphoSitePlus	CCLE	2.638	Up-regulation
CMGC_MAPK_JNK_MAPK8_ST	P22736	NR4A1	P45983	MAPK8	S237	H239Y	239	Missense	proximal	2	no	7.804	7.611	EPSD	CCLE	2.638	Down-regulation
CMGC_MAPK_JNK_MAPK8_ST	P22736	NR4A1	P45983	MAPK8	S360	S367F	367	Missense	distal	7	no	7.129	7.204	EPSD	CCLE	2.638	Up-regulation
CMGC_MAPK_JNK_MAPK8_ST	Q6SZW1	SARM1	P45983	MAPK8	S54	R51L	51	Missense	distal	-3	no	7.357	7.321	EPSD	CCLE	2.638	Down-regulation
CMGC_MAPK_JNK_MAPK8_ST	P19793	RXRA	P45983	MAPK8	S21	R25Q	25	Missense	distal	4	no	9.786	10.020	EPSD	CCLE	2.638	Up-regulation
CMGC_MAPK_JNK_MAPK8_ST	P19793	RXRA	P45983	MAPK8	S49	S52I	52	Missense	distal	3	no	7.546	7.670	EPSD	CCLE	2.638	Up-regulation
CMGC_MAPK_JNK_MAPK8_ST	P19793	RXRA	P45983	MAPK8	T82	M77I	77	Missense	distal	-5	no	9.219	8.982	EPSD	CCLE	2.638	Down-regulation
CMGC_MAPK_JNK_MAPK8_ST	P19793	RXRA	P45983	MAPK8	S225	N227S	227	Missense	proximal	2	no	4.684	4.946	EPSD	CCLE	2.638	Up-regulation
CMGC_MAPK_JNK_MAPK8_ST	O43379	WDR62	P45983	MAPK8	S1008	P1011S	1011	Missense	distal	3	no	11.467	11.342	EPSD	CCLE	2.638	Down-regulation
CMGC_MAPK_JNK_MAPK8_ST	O43379	WDR62	P45983	MAPK8	S1144	R1137T	1137	Missense	distal	-7	no	9.398	9.386	EPSD	CCLE	2.638	Down-regulation
CMGC_MAPK_JNK_MAPK8_ST	O43379	WDR62	P45983	MAPK8	T1159	L1160P	1160	Missense	proximal	1	no	1.483	9.055	EPSD	CCLE	2.638	Gain
CMGC_MAPK_JNK_MAPK8_ST	O43379	WDR62	P45983	MAPK8	T1265	I1263L	1263	Missense	proximal	-2	no	2.899	2.810	EPSD	CCLE	2.638	Down-regulation
CMGC_MAPK_JNK_MAPK8_ST	O43379	WDR62	P45983	MAPK8	T1268	I1263L	1263	Missense	distal	-5	no	8.334	8.602	EPSD	CCLE	2.638	Up-regulation
CMGC_MAPK_JNK_MAPK8_ST	P08047	SP1	P45983	MAPK8	T278	V284G	284	Missense	distal	6	no	8.327	8.349	PhosphoSitePlus;EPSD	CCLE	2.638	Up-regulation
CMGC_MAPK_JNK_MAPK8_ST	P49023	PXN	P45983	MAPK8	S178	S178N	178	Missense	central	0	yes	7.918	0.000	PhosphoSitePlus	CCLE	2.638	Loss
CMGC_MAPK_JNK_MAPK8_ST	P49023	PXN	P45983	MAPK8	S230	V237M	237	Missense	distal	7	no	8.290	8.273	EPSD	CCLE	2.638	Down-regulation
CMGC_MAPK_JNK_MAPK8_ST	P49023	PXN	P45983	MAPK8	S244	E241K	241	Missense	distal	-3	no	8.587	8.614	EPSD	CCLE	2.638	Up-regulation
CMGC_MAPK_JNK_MAPK8_ST	P49023	PXN	P45983	MAPK8	S244	V237M	237	Missense	distal	-7	no	8.587	8.584	EPSD	CCLE	2.638	Down-regulation
CMGC_MAPK_JNK_MAPK8_ST	P31947	SFN	P45983	MAPK8	S186	Y181H	181	Missense	distal	-5	no	9.620	9.328	PhosphoSitePlus	CCLE	2.638	Down-regulation
CMGC_MAPK_JNK_MAPK8_ST	Q9UQF2	MAPK8IP1	P45983	MAPK8	T103	D98G	98	Missense	distal	-5	no	8.001	8.153	EPSD;PhosphoSitePlus	CCLE	2.638	Up-regulation
CMGC_MAPK_JNK_MAPK8_ST	Q9UQF2	MAPK8IP1	P45983	MAPK8	S214	D215V	215	Missense	proximal	1	no	2.654	0.216	EPSD	CCLE	2.638	Loss
CMGC_MAPK_JNK_MAPK8_ST	Q9UQF2	MAPK8IP1	P45983	MAPK8	S214	Q220K	220	Missense	distal	6	no	2.654	2.686	EPSD	CCLE	2.638	Up-regulation
CMGC_MAPK_JNK_MAPK8_ST	Q9UQF2	MAPK8IP1	P45983	MAPK8	S341	D337N	337	Missense	distal	-4	no	8.796	8.489	EPSD	CCLE	2.638	Down-regulation
CMGC_MAPK_JNK_MAPK8_ST	Q9UQF2	MAPK8IP1	P45983	MAPK8	S341	S340L	340	Missense	proximal	-1	no	8.796	8.767	EPSD	CCLE	2.638	Down-regulation
CMGC_MAPK_JNK_MAPK8_ST	Q07817	BCL2L1	P45983	MAPK8	T47	E42D	42	Missense	distal	-5	no	7.989	8.232	PhosphoSitePlus;EPSD	CCLE	2.638	Up-regulation
CMGC_MAPK_JNK_MAPK8_ST	Q07817	BCL2L1	P45983	MAPK8	S62	S62N	62	Missense	central	0	yes	6.612	0.000	EPSD;PhosphoSitePlus	CCLE	2.638	Loss
CMGC_MAPK_JNK_MAPK8_ST	O43561	LAT	P45983	MAPK8	S41	S41L	41	Missense	central	0	yes	2.753	0.000	EPSD	CCLE	2.638	Loss
CMGC_MAPK_JNK_MAPK8_ST	O43561	LAT	P45983	MAPK8	S209	E208K	208	Missense	proximal	-1	no	2.910	2.913	EPSD	CCLE	2.638	Up-regulation
CMGC_MAPK_JNK_MAPK8_ST	Q13950	RUNX2	P45983	MAPK8	S28	S32R	32	Missense	distal	4	no	6.942	6.577	EPSD	CCLE	2.638	Down-regulation
CMGC_MAPK_JNK_MAPK8_ST	Q13950	RUNX2	P45983	MAPK8	S118	C123Y	123	Missense	distal	5	no	6.671	6.725	PhosphoSitePlus	CCLE	2.638	Up-regulation
CMGC_MAPK_JNK_MAPK8_ST	Q13950	RUNX2	P45983	MAPK8	T200	T200I	200	Missense	central	0	yes	2.782	0.000	EPSD	CCLE	2.638	Loss
CMGC_MAPK_JNK_MAPK8_ST	Q13950	RUNX2	P45983	MAPK8	T286	T286A	286	Missense	central	0	yes	2.842	0.000	EPSD	CCLE	2.638	Loss
CMGC_MAPK_JNK_MAPK8_ST	Q13950	RUNX2	P45983	MAPK8	T286	A291T	291	Missense	distal	5	no	2.842	2.840	EPSD	CCLE	2.638	Down-regulation
CMGC_MAPK_JNK_MAPK8_ST	Q13950	RUNX2	P45983	MAPK8	S294	A291T	291	Missense	distal	-3	no	8.601	8.548	EPSD	CCLE	2.638	Down-regulation
CMGC_MAPK_JNK_MAPK8_ST	Q13950	RUNX2	P45983	MAPK8	S294	Q301K	301	Missense	distal	7	no	8.601	8.569	EPSD	CCLE	2.638	Down-regulation
CMGC_MAPK_JNK_MAPK8_ST	Q13950	RUNX2	P45983	MAPK8	S305	Q301K	301	Missense	distal	-4	no	2.720	3.113	EPSD	CCLE	2.638	Up-regulation
CMGC_MAPK_JNK_MAPK8_ST	Q13950	RUNX2	P45983	MAPK8	S465	P460L	460	Missense	distal	-5	no	5.598	5.958	EPSD	CCLE	2.638	Up-regulation
CMGC_MAPK_JNK_MAPK8_ST	Q14934	NFATC4	P45983	MAPK8	S168	S174N	174	Missense	distal	6	no	7.207	7.142	EPSD	CCLE	2.638	Down-regulation
CMGC_MAPK_JNK_MAPK8_ST	Q14934	NFATC4	P45983	MAPK8	S170	S174N	174	Missense	distal	4	no	6.016	5.568	EPSD	CCLE	2.638	Down-regulation
CMGC_MAPK_JNK_MAPK8_ST	Q14934	NFATC4	P45983	MAPK8	S217	S221F	221	Missense	distal	4	no	7.333	6.875	PhosphoSitePlus;EPSD	CCLE	2.638	Down-regulation
CMGC_MAPK_JNK_MAPK8_ST	Q14934	NFATC4	P45983	MAPK8	S221	S221F	221	Missense	central	0	yes	7.409	0.000	EPSD	CCLE	2.638	Loss
CMGC_MAPK_JNK_MAPK8_ST	Q14934	NFATC4	P45983	MAPK8	T226	S221F	221	Missense	distal	-5	no	7.296	7.765	EPSD	CCLE	2.638	Up-regulation
CMGC_MAPK_JNK_MAPK8_ST	Q14934	NFATC4	P45983	MAPK8	S592	A590T	590	Missense	proximal	-2	no	5.352	5.323	EPSD	CCLE	2.638	Down-regulation
CMGC_MAPK_JNK_MAPK8_ST	Q14934	NFATC4	P45983	MAPK8	S716	P720L	720	Missense	distal	4	no	8.381	7.974	EPSD	CCLE	2.638	Down-regulation
CMGC_MAPK_JNK_MAPK8_ST	Q14934	NFATC4	P45983	MAPK8	S819	P820L	820	Missense	proximal	1	no	6.902	-0.671	EPSD	CCLE	2.638	Loss
CMGC_MAPK_JNK_MAPK8_ST	P17535	JUND	P45983	MAPK8	T3	D8H	8	Missense	distal	5	no	6.774	6.778	EPSD	CCLE	2.638	Up-regulation
CMGC_MAPK_JNK_MAPK8_ST	P17535	JUND	P45983	MAPK8	S21	P28L	28	Missense	distal	7	no	2.935	2.974	EPSD	CCLE	2.638	Up-regulation
CMGC_MAPK_JNK_MAPK8_ST	P17535	JUND	P45983	MAPK8	S21	G20V	20	Missense	proximal	-1	no	2.935	2.925	EPSD	CCLE	2.638	Down-regulation
CMGC_MAPK_JNK_MAPK8_ST	P17535	JUND	P45983	MAPK8	S27	P28L	28	Missense	proximal	1	no	8.688	1.115	EPSD	CCLE	2.638	Loss
CMGC_MAPK_JNK_MAPK8_ST	P17535	JUND	P45983	MAPK8	S27	G20V	20	Missense	distal	-7	no	8.688	8.693	EPSD	CCLE	2.638	Up-regulation
CMGC_MAPK_JNK_MAPK8_ST	P17535	JUND	P45983	MAPK8	S90	D92N	92	Missense	proximal	2	no	5.518	5.393	EPSD	CCLE	2.638	Down-regulation
CMGC_MAPK_JNK_MAPK8_ST	P17535	JUND	P45983	MAPK8	S90	L88F	88	Missense	proximal	-2	no	5.518	5.491	EPSD	CCLE	2.638	Down-regulation
CMGC_MAPK_JNK_MAPK8_ST	P85298	ARHGAP8	P45983	MAPK8	S455	M458V	458	Missense	distal	3	no	8.633	8.673	PhosphoSitePlus	CCLE	2.638	Up-regulation
CMGC_MAPK_JNK_MAPK8_ST	P10415	BCL2	P45983	MAPK8	S70	Q73H	73	Missense	distal	3	no	7.351	7.458	PhosphoSitePlus;EPSD	CCLE	2.638	Up-regulation
CMGC_MAPK_JNK_MAPK8_ST	P10415	BCL2	P45983	MAPK8	T74	Q73H	73	Missense	proximal	-1	no	9.142	9.127	EPSD	CCLE	2.638	Down-regulation
CMGC_MAPK_JNK_MAPK8_ST	P10415	BCL2	P45983	MAPK8	S87	P88R	88	Missense	proximal	1	no	7.709	0.573	EPSD;PhosphoSitePlus	CCLE	2.638	Loss
CMGC_MAPK_JNK_MAPK8_ST	P10415	BCL2	P45983	MAPK8	S87	A82T	82	Missense	distal	-5	no	7.709	7.725	EPSD;PhosphoSitePlus	CCLE	2.638	Up-regulation
CMGC_MAPK_JNK_MAPK8_ST	Q9Y6Q9	NCOA3	P45983	MAPK8	S214	P215L	215	Missense	proximal	1	no	7.609	0.036	EPSD	CCLE	2.638	Loss
CMGC_MAPK_JNK_MAPK8_ST	Q9Y6Q9	NCOA3	P45983	MAPK8	S569	Q565H	565	Missense	distal	-4	no	8.341	7.879	EPSD	CCLE	2.638	Down-regulation
CMGC_MAPK_JNK_MAPK8_ST	Q9Y6Q9	NCOA3	P45983	MAPK8	T914	T910A	910	Missense	distal	-4	no	8.452	8.489	EPSD	CCLE	2.638	Up-regulation
CMGC_MAPK_JNK_MAPK8_ST	Q15672	TWIST1	P45983	MAPK8	S8	S6C	6	Missense	proximal	-2	no	6.935	6.871	EPSD	CCLE	2.638	Down-regulation
CMGC_MAPK_JNK_MAPK8_ST	Q15672	TWIST1	P45983	MAPK8	S8	D4E	4	Missense	distal	-4	no	6.935	7.358	EPSD	CCLE	2.638	Up-regulation
CMGC_MAPK_JNK_MAPK8_ST	Q15672	TWIST1	P45983	MAPK8	S11	S6C	6	Missense	distal	-5	no	8.307	8.612	EPSD	CCLE	2.638	Up-regulation
CMGC_MAPK_JNK_MAPK8_ST	Q15672	TWIST1	P45983	MAPK8	S11	D4E	4	Missense	distal	-7	no	8.307	8.298	EPSD	CCLE	2.638	Down-regulation
CMGC_MAPK_JNK_MAPK8_ST	Q15672	TWIST1	P45983	MAPK8	S42	G36V	36	Missense	distal	-6	no	2.687	2.740	EPSD	CCLE	2.638	Up-regulation
CMGC_MAPK_JNK_MAPK8_ST	Q9NR28	DIABLO	P45983	MAPK8	S6	K5Q	5	Missense	proximal	-1	no	3.765	3.753	EPSD;PhosphoSitePlus	CCLE	2.638	Down-regulation
CMGC_MAPK_JNK_MAPK8_ST	Q9NR28	DIABLO	P45983	MAPK8	S9	S14L	14	Missense	distal	5	no	2.968	3.049	PhosphoSitePlus;EPSD	CCLE	2.638	Up-regulation
CMGC_MAPK_JNK_MAPK8_ST	Q9NR28	DIABLO	P45983	MAPK8	S9	K5Q	5	Missense	distal	-4	no	2.968	2.574	PhosphoSitePlus;EPSD	CCLE	2.638	Loss
CMGC_MAPK_JNK_MAPK8_ST	Q9UGP4	LIMD1	P45983	MAPK8	S187	N182S	182	Missense	distal	-5	no	7.606	7.175	EPSD	CCLE	2.638	Down-regulation
CMGC_MAPK_JNK_MAPK8_ST	Q9UGP4	LIMD1	P45983	MAPK8	S421	S421N	421	Missense	central	0	yes	6.910	0.000	EPSD;PhosphoSitePlus	CCLE	2.638	Loss
CMGC_MAPK_JNK_MAPK8_ST	Q9UGP4	LIMD1	P45983	MAPK8	S424	S421N	421	Missense	distal	-3	no	8.533	8.180	EPSD;PhosphoSitePlus	CCLE	2.638	Down-regulation
CMGC_MAPK_JNK_MAPK8_ST	Q99607	ELF4	P45983	MAPK8	S641	S648P	648	Missense	distal	7	no	8.197	8.235	PhosphoSitePlus	CCLE	2.638	Up-regulation
CMGC_MAPK_JNK_MAPK8_ST	Q99607	ELF4	P45983	MAPK8	T643	S648P	648	Missense	distal	5	no	6.925	7.008	EPSD	CCLE	2.638	Up-regulation
CMGC_MAPK_JNK_MAPK8_ST	Q99607	ELF4	P45983	MAPK8	S648	S648P	648	Missense	central	0	yes	7.748	0.000	EPSD	CCLE	2.638	Loss
CMGC_MAPK_JNK_MAPK8_ST	Q14451	GRB7	P45983	MAPK8	S6	P8R	8	Missense	proximal	2	no	8.652	8.596	EPSD	CCLE	2.638	Down-regulation
CMGC_MAPK_JNK_MAPK8_ST	Q14451	GRB7	P45983	MAPK8	S13	P8R	8	Missense	distal	-5	no	6.680	6.972	EPSD	CCLE	2.638	Up-regulation
CMGC_MAPK_JNK_MAPK8_ST	P30305	CDC25B	P45983	MAPK8	S15	A13D	13	Missense	proximal	-2	no	7.907	7.832	EPSD	CCLE	2.638	Down-regulation
CMGC_MAPK_JNK_MAPK8_ST	P30305	CDC25B	P45983	MAPK8	S42	G41W	41	Missense	proximal	-1	no	8.088	8.083	EPSD	CCLE	2.638	Down-regulation
CMGC_MAPK_JNK_MAPK8_ST	P30305	CDC25B	P45983	MAPK8	S42	V44G	44	Missense	proximal	2	no	8.088	8.179	EPSD	CCLE	2.638	Up-regulation
CMGC_MAPK_JNK_MAPK8_ST	P30305	CDC25B	P45983	MAPK8	S42	R45Q	45	Missense	distal	3	no	8.088	7.962	EPSD	CCLE	2.638	Down-regulation
CMGC_MAPK_JNK_MAPK8_ST	P30305	CDC25B	P45983	MAPK8	S50	V44G	44	Missense	distal	-6	no	9.900	9.847	EPSD	CCLE	2.638	Down-regulation
CMGC_MAPK_JNK_MAPK8_ST	P30305	CDC25B	P45983	MAPK8	S50	R45Q	45	Missense	distal	-5	no	9.900	9.585	EPSD	CCLE	2.638	Down-regulation
CMGC_MAPK_JNK_MAPK8_ST	P30305	CDC25B	P45983	MAPK8	T69	K71E	71	Missense	proximal	2	no	7.377	7.359	EPSD	CCLE	2.638	Down-regulation
CMGC_MAPK_JNK_MAPK8_ST	P30305	CDC25B	P45983	MAPK8	T69	K71T	71	Missense	proximal	2	no	7.377	7.299	EPSD	CCLE	2.638	Down-regulation
CMGC_MAPK_JNK_MAPK8_ST	P30305	CDC25B	P45983	MAPK8	S321	C315F	315	Missense	distal	-6	no	9.454	9.505	EPSD	CCLE	2.638	Up-regulation
CMGC_MAPK_JNK_MAPK8_ST	P30305	CDC25B	P45983	MAPK8	S416	L412H	412	Missense	distal	-4	no	6.895	7.143	EPSD	CCLE	2.638	Up-regulation
CMGC_MAPK_JNK_MAPK8_ST	Q07820	MCL1	P45983	MAPK8	T70	R74L	74	Missense	distal	4	no	6.137	6.070	EPSD	CCLE	2.638	Down-regulation
CMGC_MAPK_JNK_MAPK8_ST	Q07820	MCL1	P45983	MAPK8	T70	R74Q	74	Missense	distal	4	no	6.137	6.370	EPSD	CCLE	2.638	Up-regulation
CMGC_MAPK_JNK_MAPK8_ST	Q07820	MCL1	P45983	MAPK8	T70	S73P	73	Missense	distal	3	no	6.137	6.262	EPSD	CCLE	2.638	Up-regulation
CMGC_MAPK_JNK_MAPK8_ST	Q07820	MCL1	P45983	MAPK8	T92	D88N	88	Missense	distal	-4	no	7.127	6.819	EPSD	CCLE	2.638	Down-regulation
CMGC_MAPK_JNK_MAPK8_ST	Q07820	MCL1	P45983	MAPK8	T163	T156R	156	Missense	distal	-7	no	8.911	8.923	EPSD;PhosphoSitePlus	CCLE	2.638	Up-regulation
CMGC_MAPK_JNK_MAPK8_ST	Q8WYQ5	DGCR8	P45983	MAPK8	S95	A102T	102	Missense	distal	7	no	10.575	10.577	EPSD	CCLE	2.638	Up-regulation
CMGC_MAPK_JNK_MAPK8_ST	Q8WYQ5	DGCR8	P45983	MAPK8	S109	A102T	102	Missense	distal	-7	no	6.871	6.873	EPSD	CCLE	2.638	Up-regulation
CMGC_MAPK_JNK_MAPK8_ST	Q8WYQ5	DGCR8	P45983	MAPK8	T371	G374E	374	Missense	distal	3	no	6.340	6.163	EPSD	CCLE	2.638	Down-regulation
CMGC_MAPK_JNK_MAPK8_ST	Q8WYQ5	DGCR8	P45983	MAPK8	T371	V376M	376	Missense	distal	5	no	6.340	6.331	EPSD	CCLE	2.638	Down-regulation
CMGC_MAPK_JNK_MAPK8_ST	Q8WYQ5	DGCR8	P45983	MAPK8	S377	G374E	374	Missense	distal	-3	no	7.335	7.668	EPSD	CCLE	2.638	Up-regulation
CMGC_MAPK_JNK_MAPK8_ST	Q8WYQ5	DGCR8	P45983	MAPK8	S377	V376M	376	Missense	proximal	-1	no	7.335	7.343	EPSD	CCLE	2.638	Up-regulation
CMGC_MAPK_JNK_MAPK8_ST	Q8N122	RPTOR	P45983	MAPK8	S8	E2Q	2	Missense	distal	-6	no	6.626	6.686	EPSD	CCLE	2.638	Up-regulation
CMGC_MAPK_JNK_MAPK8_ST	Q8N122	RPTOR	P45983	MAPK8	S898	R899Q	899	Missense	proximal	1	no	3.303	3.330	EPSD	CCLE	2.638	Up-regulation
CMGC_MAPK_JNK_MAPK8_ST	P04637	TP53	P45983	MAPK8	S33	E28Q	28	Missense	distal	-5	no	7.176	7.284	EPSD	CCLE	2.638	Up-regulation
CMGC_MAPK_JNK_MAPK8_ST	Q96FI4	NEIL1	P45983	MAPK8	S61	P62L	62	Missense	proximal	1	no	8.363	0.790	EPSD;PhosphoSitePlus	CCLE	2.638	Loss
CMGC_MAPK_JNK_MAPK8_ST	Q12904	AIMP1	P45983	MAPK8	S232	M226V	226	Missense	distal	-6	no	7.749	7.789	EPSD	CCLE	2.638	Up-regulation
CMGC_MAPK_JNK_MAPK8_ST	P37231	PPARG	P45983	MAPK8	S273	M280I	280	Missense	distal	7	no	7.718	7.690	EPSD	CCLE	2.638	Down-regulation
CMGC_MAPK_JNK_MAPK8_ST	P29966	MARCKS	P45983	MAPK8	S27	A25T	25	Missense	proximal	-2	no	9.143	9.113	EPSD	CCLE	2.638	Down-regulation
CMGC_MAPK_JNK_MAPK8_ST	P29966	MARCKS	P45983	MAPK8	S46	A50T	50	Missense	distal	4	no	7.118	7.070	PhosphoSitePlus	CCLE	2.638	Down-regulation
CMGC_MAPK_JNK_MAPK8_ST	P29966	MARCKS	P45983	MAPK8	S81	A79V	79	Missense	proximal	-2	no	7.965	7.774	EPSD	CCLE	2.638	Down-regulation
CMGC_MAPK_JNK_MAPK8_ST	P29966	MARCKS	P45983	MAPK8	S81	A84S	84	Missense	distal	3	no	7.965	7.946	EPSD	CCLE	2.638	Down-regulation
CMGC_MAPK_JNK_MAPK8_ST	P29966	MARCKS	P45983	MAPK8	S101	A95G	95	Missense	distal	-6	no	8.818	8.966	EPSD	CCLE	2.638	Up-regulation
CMGC_MAPK_JNK_MAPK8_ST	P29966	MARCKS	P45983	MAPK8	S101	E106K	106	Missense	distal	5	no	8.818	8.810	EPSD	CCLE	2.638	Down-regulation
CMGC_MAPK_JNK_MAPK8_ST	P29966	MARCKS	P45983	MAPK8	S118	E123K	123	Missense	distal	5	no	7.692	7.684	EPSD	CCLE	2.638	Down-regulation
CMGC_MAPK_JNK_MAPK8_ST	P29966	MARCKS	P45983	MAPK8	S118	E123A	123	Missense	distal	5	no	7.692	7.711	EPSD	CCLE	2.638	Up-regulation
CMGC_MAPK_JNK_MAPK8_ST	P29966	MARCKS	P45983	MAPK8	S118	G124R	124	Missense	distal	6	no	7.692	7.689	EPSD	CCLE	2.638	Down-regulation
CMGC_MAPK_JNK_MAPK8_ST	P29966	MARCKS	P45983	MAPK8	S135	P136L	136	Missense	proximal	1	no	8.101	0.528	EPSD	CCLE	2.638	Loss
CMGC_MAPK_JNK_MAPK8_ST	P29966	MARCKS	P45983	MAPK8	T143	P136L	136	Missense	distal	-7	no	6.452	6.463	EPSD	CCLE	2.638	Up-regulation
CMGC_MAPK_JNK_MAPK8_ST	P29966	MARCKS	P45983	MAPK8	T143	S145A	145	Missense	proximal	2	no	6.452	6.476	EPSD	CCLE	2.638	Up-regulation
CMGC_MAPK_JNK_MAPK8_ST	P29966	MARCKS	P45983	MAPK8	S145	S145A	145	Missense	central	0	yes	8.513	0.000	EPSD	CCLE	2.638	Loss
CMGC_MAPK_JNK_MAPK8_ST	P29966	MARCKS	P45983	MAPK8	T150	S145A	145	Missense	distal	-5	no	6.660	6.644	EPSD	CCLE	2.638	Down-regulation
CMGC_MAPK_JNK_MAPK8_ST	Q8N6T7	SIRT6	P45983	MAPK8	S330	E334K	334	Missense	distal	4	no	9.096	9.177	EPSD	CCLE	2.638	Up-regulation
CMGC_MAPK_JNK_MAPK8_ST	Q8N6T7	SIRT6	P45983	MAPK8	S338	E334K	334	Missense	distal	-4	no	9.406	9.662	EPSD	CCLE	2.638	Up-regulation
CMGC_MAPK_JNK_MAPK8_ST	Q7KZF4	SND1	P45983	MAPK8	T103	R107Q	107	Missense	distal	4	no	8.214	8.447	PhosphoSitePlus	CCLE	2.638	Up-regulation
CMGC_MAPK_JNK_MAPK8_ST	Q7KZF4	SND1	P45983	MAPK8	S426	A428S	428	Missense	proximal	2	no	9.196	9.171	EPSD	CCLE	2.638	Down-regulation
CMGC_MAPK_JNK_MAPK8_ST	P11802	CDK4	P45983	MAPK8	S166	A170T	170	Missense	distal	4	no	3.246	3.197	EPSD	CCLE	2.638	Down-regulation
CMGC_MAPK_JNK_MAPK8_ST	P11802	CDK4	P45983	MAPK8	T172	A170T	170	Missense	proximal	-2	no	6.276	6.246	PhosphoSitePlus	CCLE	2.638	Down-regulation
CMGC_MAPK_JNK_MAPK8_ST	O95644	NFATC1	P45983	MAPK8	S117	R119L	119	Missense	proximal	2	no	7.644	7.623	EPSD	CCLE	2.638	Down-regulation
CMGC_MAPK_JNK_MAPK8_ST	O95644	NFATC1	P45983	MAPK8	S117	T123N	123	Missense	distal	6	no	7.644	7.582	EPSD	CCLE	2.638	Down-regulation
CMGC_MAPK_JNK_MAPK8_ST	O95644	NFATC1	P45983	MAPK8	S172	S176I	176	Missense	distal	4	no	9.471	9.281	PhosphoSitePlus	CCLE	2.638	Down-regulation
CMGC_MAPK_JNK_MAPK8_ST	O95644	NFATC1	P45983	MAPK8	S172	S179P	179	Missense	distal	7	no	9.471	9.509	PhosphoSitePlus	CCLE	2.638	Up-regulation
CMGC_MAPK_JNK_MAPK8_ST	O95644	NFATC1	P45983	MAPK8	S178	S179P	179	Missense	proximal	1	no	-0.797	6.932	EPSD	CCLE	2.638	Gain
CMGC_MAPK_JNK_MAPK8_ST	O95644	NFATC1	P45983	MAPK8	S211	S207F	207	Missense	distal	-4	no	8.735	7.797	EPSD	CCLE	2.638	Down-regulation
CMGC_MAPK_JNK_MAPK8_ST	O95644	NFATC1	P45983	MAPK8	S233	R235Q	235	Missense	proximal	2	no	8.750	8.924	EPSD	CCLE	2.638	Up-regulation
CMGC_MAPK_JNK_MAPK8_ST	O95644	NFATC1	P45983	MAPK8	S237	R235Q	235	Missense	proximal	-2	no	9.190	9.264	EPSD	CCLE	2.638	Up-regulation
CMGC_MAPK_JNK_MAPK8_ST	O95644	NFATC1	P45983	MAPK8	S237	R243C	243	Missense	distal	6	no	9.190	9.202	EPSD	CCLE	2.638	Up-regulation
CMGC_MAPK_JNK_MAPK8_ST	O95644	NFATC1	P45983	MAPK8	S241	R235Q	235	Missense	distal	-6	no	9.684	9.582	EPSD	CCLE	2.638	Down-regulation
CMGC_MAPK_JNK_MAPK8_ST	O95644	NFATC1	P45983	MAPK8	S241	R243C	243	Missense	proximal	2	no	9.684	9.732	EPSD	CCLE	2.638	Up-regulation
CMGC_MAPK_JNK_MAPK8_ST	O95644	NFATC1	P45983	MAPK8	S241	S245I	245	Missense	distal	4	no	9.684	9.494	EPSD	CCLE	2.638	Down-regulation
CMGC_MAPK_JNK_MAPK8_ST	O95644	NFATC1	P45983	MAPK8	S261	N264S	264	Missense	distal	3	no	9.415	9.212	EPSD	CCLE	2.638	Down-regulation
CMGC_MAPK_JNK_MAPK8_ST	O95644	NFATC1	P45983	MAPK8	S278	R273W	273	Missense	distal	-5	no	11.304	11.350	EPSD	CCLE	2.638	Up-regulation
CMGC_MAPK_JNK_MAPK8_ST	O95644	NFATC1	P45983	MAPK8	S282	P287S	287	Missense	distal	5	no	9.467	9.384	EPSD	CCLE	2.638	Down-regulation
CMGC_MAPK_JNK_MAPK8_ST	O95644	NFATC1	P45983	MAPK8	T284	P287S	287	Missense	distal	3	no	7.545	7.420	EPSD	CCLE	2.638	Down-regulation
CMGC_MAPK_JNK_MAPK8_ST	O95644	NFATC1	P45983	MAPK8	S286	P287S	287	Missense	proximal	1	no	9.189	1.460	EPSD	CCLE	2.638	Loss
CMGC_MAPK_JNK_MAPK8_ST	O95644	NFATC1	P45983	MAPK8	S290	P287S	287	Missense	distal	-3	no	8.101	8.263	EPSD	CCLE	2.638	Up-regulation
CMGC_MAPK_JNK_MAPK8_ST	O95644	NFATC1	P45983	MAPK8	S359	G358V	358	Missense	proximal	-1	no	8.671	8.662	EPSD	CCLE	2.638	Down-regulation
CMGC_MAPK_JNK_MAPK8_ST	O95644	NFATC1	P45983	MAPK8	S403	Y407C	407	Missense	distal	4	no	8.267	8.461	EPSD	CCLE	2.638	Up-regulation
CMGC_MAPK_JNK_MAPK8_ST	O95644	NFATC1	P45983	MAPK8	S409	Y407C	407	Missense	proximal	-2	no	11.202	11.266	EPSD	CCLE	2.638	Up-regulation
CMGC_MAPK_JNK_MAPK8_ST	O95644	NFATC1	P45983	MAPK8	S447	R448W	448	Missense	proximal	1	no	2.059	3.522	EPSD	CCLE	2.638	Gain
CMGC_MAPK_JNK_MAPK8_ST	O95644	NFATC1	P45983	MAPK8	S670	V672A	672	Missense	proximal	2	no	8.923	9.241	EPSD	CCLE	2.638	Up-regulation
CMGC_MAPK_JNK_MAPK8_ST	O95644	NFATC1	P45983	MAPK8	S670	H673R	673	Missense	distal	3	no	8.923	8.942	EPSD	CCLE	2.638	Up-regulation
CMGC_MAPK_JNK_MAPK8_ST	O95644	NFATC1	P45983	MAPK8	S670	S675G	675	Missense	distal	5	no	8.923	8.992	EPSD	CCLE	2.638	Up-regulation
CMGC_MAPK_JNK_MAPK8_ST	O95644	NFATC1	P45983	MAPK8	S772	T777P	777	Missense	distal	5	no	5.824	5.900	EPSD	CCLE	2.638	Up-regulation
CMGC_MAPK_JNK_MAPK8_ST	O95644	NFATC1	P45983	MAPK8	S782	T777P	777	Missense	distal	-5	no	6.523	6.635	EPSD	CCLE	2.638	Up-regulation
CMGC_MAPK_JNK_MAPK8_ST	O95644	NFATC1	P45983	MAPK8	S903	I909M	909	Missense	distal	6	no	8.141	8.111	EPSD	CCLE	2.638	Down-regulation
CMGC_MAPK_JNK_MAPK8_ST	Q96P20	NLRP3	P45983	MAPK8	S387	S387F	387	Missense	central	0	yes	2.719	0.000	EPSD	CCLE	2.638	Loss
CMGC_MAPK_JNK_MAPK8_ST	P10275	AR	P45983	MAPK8	S96	Q98R	98	Missense	proximal	2	no	7.626	7.451	EPSD	CCLE	2.638	Down-regulation
CMGC_MAPK_JNK_MAPK8_ST	P35568	IRS1	P45983	MAPK8	S307	A314D	314	Missense	distal	7	no	4.798	4.833	EPSD	CCLE	2.638	Up-regulation
CMGC_MAPK_JNK_MAPK8_ST	P35568	IRS1	P45983	MAPK8	S307	R304H	304	Missense	distal	-3	no	4.798	4.835	EPSD	CCLE	2.638	Up-regulation
CMGC_MAPK_JNK_MAPK8_ST	P35568	IRS1	P45983	MAPK8	S307	R302Q	302	Missense	distal	-5	no	4.798	4.483	EPSD	CCLE	2.638	Down-regulation
CMGC_MAPK_JNK_MAPK8_ST	P35568	IRS1	P45983	MAPK8	T309	A314D	314	Missense	distal	5	no	2.934	2.972	EPSD	CCLE	2.638	Up-regulation
CMGC_MAPK_JNK_MAPK8_ST	P35568	IRS1	P45983	MAPK8	T309	R304H	304	Missense	distal	-5	no	2.934	2.839	EPSD	CCLE	2.638	Down-regulation
CMGC_MAPK_JNK_MAPK8_ST	P35568	IRS1	P45983	MAPK8	T309	R302Q	302	Missense	distal	-7	no	2.934	2.924	EPSD	CCLE	2.638	Down-regulation
CMGC_MAPK_JNK_MAPK8_ST	P35568	IRS1	P45983	MAPK8	S312	A314D	314	Missense	proximal	2	no	8.564	8.403	PhosphoSitePlus	CCLE	2.638	Down-regulation
CMGC_MAPK_JNK_MAPK8_ST	P35568	IRS1	P45983	MAPK8	S402	T403P	403	Missense	proximal	1	no	0.847	7.833	EPSD	CCLE	2.638	Gain
CMGC_MAPK_JNK_MAPK8_ST	P35568	IRS1	P45983	MAPK8	S531	P532S	532	Missense	proximal	1	no	9.776	2.047	EPSD	CCLE	2.638	Loss
CMGC_MAPK_JNK_MAPK8_ST	P35568	IRS1	P45983	MAPK8	S672	P679R	679	Missense	distal	7	no	9.197	9.221	EPSD	CCLE	2.638	Up-regulation
CMGC_MAPK_JNK_MAPK8_ST	P35568	IRS1	P45983	MAPK8	S736	V738M	738	Missense	proximal	2	no	6.755	6.800	EPSD	CCLE	2.638	Up-regulation
CMGC_MAPK_JNK_MAPK8_ST	P35568	IRS1	P45983	MAPK8	S745	S747A	747	Missense	proximal	2	no	8.391	8.415	EPSD	CCLE	2.638	Up-regulation
CMGC_MAPK_JNK_MAPK8_ST	P35568	IRS1	P45983	MAPK8	S745	V738M	738	Missense	distal	-7	no	8.391	8.388	EPSD	CCLE	2.638	Down-regulation
CMGC_MAPK_JNK_MAPK8_ST	P35568	IRS1	P45983	MAPK8	T1107	S1105F	1105	Missense	proximal	-2	no	7.378	7.263	EPSD	CCLE	2.638	Down-regulation
CMGC_MAPK_JNK_MAPK8_ST	P35568	IRS1	P45983	MAPK8	S1109	S1105F	1105	Missense	distal	-4	no	2.694	1.756	EPSD	CCLE	2.638	Loss
CMGC_MAPK_JNK_MAPK8_ST	P35568	IRS1	P45983	MAPK8	S1143	E1136K	1136	Missense	distal	-7	no	3.274	3.271	EPSD	CCLE	2.638	Down-regulation
CMGC_MAPK_JNK_MAPK8_ST	P61978	HNRNPK	P45983	MAPK8	S116	T120I	120	Missense	distal	4	no	7.091	6.950	EPSD	CCLE	2.638	Down-regulation
CMGC_MAPK_JNK_MAPK8_ST	P61978	HNRNPK	P45983	MAPK8	S216	R221C	221	Missense	distal	5	no	7.728	7.709	EPSD;PhosphoSitePlus	CCLE	2.638	Down-regulation
CMGC_MAPK_JNK_MAPK8_ST	P31946	YWHAB	P45983	MAPK8	S186	P187S	187	Missense	proximal	1	no	9.350	1.621	PhosphoSitePlus	CCLE	2.638	Loss
CMGC_MAPK_JNK_MAPK8_ST	Q9NZ72	STMN3	P45983	MAPK8	S6	Y8C	8	Missense	proximal	2	no	2.777	2.961	EPSD	CCLE	2.638	Up-regulation
CMGC_MAPK_JNK_MAPK8_ST	Q9NZ72	STMN3	P45983	MAPK8	S60	E67Q	67	Missense	distal	7	no	8.468	8.485	PhosphoSitePlus	CCLE	2.638	Up-regulation
CMGC_MAPK_JNK_MAPK8_ST	Q9NZ72	STMN3	P45983	MAPK8	S65	E67Q	67	Missense	proximal	2	no	8.449	8.318	EPSD	CCLE	2.638	Down-regulation
CMGC_MAPK_JNK_MAPK8_ST	Q9NZ72	STMN3	P45983	MAPK8	S68	E67Q	67	Missense	proximal	-1	no	7.193	7.183	EPSD	CCLE	2.638	Down-regulation
CMGC_MAPK_JNK_MAPK8_ST	Q9NZ72	STMN3	P45983	MAPK8	S73	E67Q	67	Missense	distal	-6	no	7.517	7.577	EPSD	CCLE	2.638	Up-regulation
CMGC_MAPK_JNK_MAPK8_ST	P04150	NR3C1	P45983	MAPK8	S395	S394L	394	Missense	proximal	-1	no	7.684	7.655	EPSD	CCLE	2.638	Down-regulation
CMGC_MAPK_JNK_MAPK8_ST	P04150	NR3C1	P45983	MAPK8	S395	G392D	392	Missense	distal	-3	no	7.684	7.778	EPSD	CCLE	2.638	Up-regulation
CMGC_MAPK_JNK_MAPK8_ST	Q9H2B2	SYT4	P45983	MAPK8	T122	T122A	122	Missense	central	0	yes	7.396	0.000	EPSD	CCLE	2.638	Loss
CAMK_CAMKL_MARK_MARK3_ST	Q06413	MEF2C	P27448	MARK3	S59	V65M	65	Missense	distal	6	no	272.923	283.536	EPSD	CCLE	255.132	Up-regulation
CAMK_CAMKL_MARK_MARK3_ST	Q06413	MEF2C	P27448	MARK3	S222	G215D	215	Missense	distal	-7	no	529.076	535.533	PhosphoSitePlus	CCLE	255.132	Up-regulation
CAMK_CAMKL_MARK_MARK3_ST	Q99689	FEZ1	P27448	MARK3	T136	E140G	140	Missense	distal	4	no	257.380	258.003	EPSD	CCLE	255.132	Up-regulation
CAMK_CAMKL_MARK_MARK3_ST	Q99689	FEZ1	P27448	MARK3	T344	T337A	337	Missense	distal	-7	no	257.141	262.161	EPSD	CCLE	255.132	Up-regulation
CAMK_CAMKL_MARK_MARK3_ST	Q92974	ARHGEF2	P27448	MARK3	S142	A147T	147	Missense	distal	5	no	286.251	274.472	EPSD	CCLE	255.132	Down-regulation
CAMK_CAMKL_MARK_MARK3_ST	Q92974	ARHGEF2	P27448	MARK3	S143	A147T	147	Missense	distal	4	no	373.920	374.155	EPSD	CCLE	255.132	Up-regulation
CAMK_CAMKL_MARK_MARK3_ST	Q92974	ARHGEF2	P27448	MARK3	S151	A147T	147	Missense	distal	-4	no	574.805	569.263	PhosphoSitePlus	CCLE	255.132	Down-regulation
CAMK_CAMKL_MARK_MARK3_ST	Q92974	ARHGEF2	P27448	MARK3	S172	R168H	168	Missense	distal	-4	no	335.738	315.206	EPSD	CCLE	255.132	Down-regulation
CAMK_CAMKL_MARK_MARK3_ST	Q92974	ARHGEF2	P27448	MARK3	S186	E193Q	193	Missense	distal	7	no	344.357	346.253	EPSD	CCLE	255.132	Up-regulation
CAMK_CAMKL_MARK_MARK3_ST	Q92974	ARHGEF2	P27448	MARK3	S696	G692S	692	Missense	distal	-4	no	263.875	281.030	EPSD	CCLE	255.132	Up-regulation
CAMK_CAMKL_MARK_MARK3_ST	Q92974	ARHGEF2	P27448	MARK3	S711	N709I	709	Missense	proximal	-2	no	271.732	262.038	EPSD	CCLE	255.132	Down-regulation
CAMK_CAMKL_MARK_MARK3_ST	P41236	PPP1R2	P27448	MARK3	S7	S7W	7	Missense	central	0	yes	327.320	0.000	EPSD	CCLE	255.132	Loss
CAMK_CAMKL_MARK_MARK3_ST	P41236	PPP1R2	P27448	MARK3	T19	S20Y	20	Missense	proximal	1	no	291.085	291.083	EPSD	CCLE	255.132	Down-regulation
CAMK_CAMKL_MARK_MARK3_ST	P41236	PPP1R2	P27448	MARK3	S20	S20Y	20	Missense	central	0	yes	482.335	0.000	EPSD	CCLE	255.132	Loss
CAMK_CAMKL_MARK_MARK3_ST	P41236	PPP1R2	P27448	MARK3	T21	S20Y	20	Missense	proximal	-1	no	299.850	299.755	EPSD	CCLE	255.132	Down-regulation
CAMK_CAMKL_MARK_MARK3_ST	P41236	PPP1R2	P27448	MARK3	S23	S20Y	20	Missense	distal	-3	no	345.708	326.467	EPSD	CCLE	255.132	Down-regulation
CAMK_CAMKL_MARK_MARK3_ST	P41236	PPP1R2	P27448	MARK3	S24	S20Y	20	Missense	distal	-4	no	311.243	304.682	EPSD	CCLE	255.132	Down-regulation
CAMK_CAMKL_MARK_MARK3_ST	P41236	PPP1R2	P27448	MARK3	S72	M79T	79	Missense	distal	7	no	555.959	555.255	PhosphoSitePlus	CCLE	255.132	Down-regulation
CAMK_CAMKL_MARK_MARK3_ST	P41236	PPP1R2	P27448	MARK3	S72	M78I	78	Missense	distal	6	no	555.959	548.413	PhosphoSitePlus	CCLE	255.132	Down-regulation
CAMK_CAMKL_MARK_MARK3_ST	P41236	PPP1R2	P27448	MARK3	T73	M79T	79	Missense	distal	6	no	309.398	314.568	EPSD	CCLE	255.132	Up-regulation
CAMK_CAMKL_MARK_MARK3_ST	P41236	PPP1R2	P27448	MARK3	T73	M78I	78	Missense	distal	5	no	309.398	295.105	EPSD	CCLE	255.132	Down-regulation
CAMK_CAMKL_MARK_MARK3_ST	P30307	CDC25C	P27448	MARK3	T236	D239H	239	Missense	distal	3	no	353.961	354.636	EPSD	CCLE	255.132	Up-regulation
AGC_Akt_AKT2_ST	Q04656	ATP7A	P31751	AKT2	S262	R269M	269	Missense	distal	7	no	26.611	26.314	EPSD	CCLE	19.022	Down-regulation
AGC_Akt_AKT2_ST	Q04656	ATP7A	P31751	AKT2	S272	R269M	269	Missense	distal	-3	no	23.452	-5.327	EPSD	CCLE	19.022	Loss
AGC_Akt_AKT2_ST	Q04656	ATP7A	P31751	AKT2	T274	R269M	269	Missense	distal	-5	no	26.304	7.790	EPSD	CCLE	19.022	Loss
AGC_Akt_AKT2_ST	Q04656	ATP7A	P31751	AKT2	S1466	S1473F	1473	Missense	distal	7	no	28.475	27.435	EPSD;PhosphoSitePlus	CCLE	19.022	Down-regulation
AGC_Akt_AKT2_ST	Q13835	PKP1	P31751	AKT2	S54	V49I	49	Missense	distal	-5	no	15.717	19.334	EPSD;PhosphoSitePlus	CCLE	19.022	Gain
AGC_Akt_AKT2_ST	Q99683	MAP3K5	P31751	AKT2	S83	R78Q	78	Missense	distal	-5	no	33.303	28.970	PhosphoSitePlus	CCLE	19.022	Down-regulation
AGC_Akt_AKT2_ST	O43464	HTRA2	P31751	AKT2	S13	G9V	9	Missense	distal	-4	no	25.953	25.762	EPSD	CCLE	19.022	Down-regulation
AGC_Akt_AKT2_ST	P15311	EZR	P31751	AKT2	S535	R529Q	529	Missense	distal	-6	no	20.541	20.517	EPSD	CCLE	19.022	Down-regulation
AGC_Akt_AKT2_ST	Q92908	GATA6	P31751	AKT2	S24	D20N	20	Missense	distal	-4	no	20.684	20.124	EPSD	CCLE	19.022	Down-regulation
AGC_Akt_AKT2_ST	Q92908	GATA6	P31751	AKT2	S377	P373L	373	Missense	distal	-4	no	20.844	21.252	EPSD	CCLE	19.022	Up-regulation
AGC_Akt_AKT2_ST	Q14315	FLNC	P31751	AKT2	T423	V424M	424	Missense	proximal	1	no	21.423	22.515	EPSD	CCLE	19.022	Up-regulation
AGC_Akt_AKT2_ST	Q14315	FLNC	P31751	AKT2	T1087	D1086N	1086	Missense	proximal	-1	no	18.197	19.520	EPSD	CCLE	19.022	Gain
AGC_Akt_AKT2_ST	Q14315	FLNC	P31751	AKT2	S2004	P1997S	1997	Missense	distal	-7	no	20.051	19.746	EPSD	CCLE	19.022	Down-regulation
AGC_Akt_AKT2_ST	Q14315	FLNC	P31751	AKT2	S2646	G2644E	2644	Missense	proximal	-2	no	20.213	19.334	EPSD	CCLE	19.022	Down-regulation
AGC_Akt_AKT2_ST	P03372	ESR1	P31751	AKT2	S236	A239D	239	Missense	distal	3	no	31.635	31.785	EPSD	CCLE	19.022	Up-regulation
AGC_Akt_AKT2_ST	Q9H0H5	RACGAP1	P31751	AKT2	S592	R599H	599	Missense	distal	7	no	21.870	21.660	EPSD	CCLE	19.022	Down-regulation
AGC_Akt_AKT2_ST	Q9H0H5	RACGAP1	P31751	AKT2	S592	P589T	589	Missense	distal	-3	no	21.870	15.540	EPSD	CCLE	19.022	Loss
AGC_Akt_AKT2_ST	Q9H0H5	RACGAP1	P31751	AKT2	S600	P607S	607	Missense	distal	7	no	22.113	22.437	EPSD	CCLE	19.022	Up-regulation
AGC_Akt_AKT2_ST	Q9H0H5	RACGAP1	P31751	AKT2	S600	R599H	599	Missense	proximal	-1	no	22.113	21.339	EPSD	CCLE	19.022	Down-regulation
AGC_Akt_AKT2_ST	Q9H0H5	RACGAP1	P31751	AKT2	S611	S615P	615	Missense	distal	4	no	19.326	19.605	EPSD	CCLE	19.022	Up-regulation
AGC_Akt_AKT2_ST	Q9H0H5	RACGAP1	P31751	AKT2	S611	P607S	607	Missense	distal	-4	no	19.326	19.442	EPSD	CCLE	19.022	Up-regulation
AGC_Akt_AKT2_ST	Q9H0H5	RACGAP1	P31751	AKT2	T617	S615P	615	Missense	proximal	-2	no	20.511	20.302	EPSD	CCLE	19.022	Down-regulation
AGC_Akt_AKT2_ST	O43516	WIPF1	P31751	AKT2	S145	R149M	149	Missense	distal	4	no	27.081	27.297	EPSD	CCLE	19.022	Up-regulation
AGC_Akt_AKT2_ST	O43516	WIPF1	P31751	AKT2	S154	R149M	149	Missense	distal	-5	no	30.343	11.829	EPSD;PhosphoSitePlus	CCLE	19.022	Loss
AGC_Akt_AKT2_ST	O43516	WIPF1	P31751	AKT2	S340	P335Q	335	Missense	distal	-5	no	22.692	22.456	EPSD	CCLE	19.022	Down-regulation
AGC_Akt_AKT2_ST	O43516	WIPF1	P31751	AKT2	S342	P335Q	335	Missense	distal	-7	no	20.655	20.251	EPSD	CCLE	19.022	Down-regulation
AGC_Akt_AKT2_ST	O43516	WIPF1	P31751	AKT2	S434	A427V	427	Missense	distal	-7	no	19.834	19.689	EPSD	CCLE	19.022	Down-regulation
AGC_Akt_AKT2_ST	Q99623	PHB2	P31751	AKT2	S96	Q100E	100	Missense	distal	4	no	19.548	19.587	EPSD	CCLE	19.022	Up-regulation
AGC_Akt_AKT2_ST	Q92945	KHSRP	P31751	AKT2	S144	S144L	144	Missense	central	0	yes	25.523	0.000	EPSD	CCLE	19.022	Loss
AGC_Akt_AKT2_ST	O60331	PIP5K1C	P31751	AKT2	S662	P660R	660	Missense	proximal	-2	no	16.776	19.565	EPSD	CCLE	19.022	Gain
AGC_Akt_AKT2_ST	O15111	CHUK	P31751	AKT2	T23	C30S	30	Missense	distal	7	no	34.368	35.231	PhosphoSitePlus	CCLE	19.022	Up-regulation
AGC_Akt_AKT2_ST	Q86YS7	C2CD5	P31751	AKT2	S301	D308H	308	Missense	distal	7	no	19.998	20.225	EPSD	CCLE	19.022	Up-regulation
AGC_Akt_AKT2_ST	Q86YS7	C2CD5	P31751	AKT2	S305	D308H	308	Missense	distal	3	no	20.551	20.411	EPSD	CCLE	19.022	Down-regulation
AGC_Akt_AKT2_ST	Q7Z6J0	SH3RF1	P31751	AKT2	T684	S679C	679	Missense	distal	-5	no	20.214	3.552	EPSD	CCLE	19.022	Loss
AGC_Akt_AKT2_ST	Q7Z6J0	SH3RF1	P31751	AKT2	S692	A696V	696	Missense	distal	4	no	23.212	23.209	EPSD	CCLE	19.022	Down-regulation
AGC_Akt_AKT2_ST	Q7Z6J0	SH3RF1	P31751	AKT2	T782	P780L	780	Missense	proximal	-2	no	19.462	19.801	EPSD	CCLE	19.022	Up-regulation
AGC_Akt_AKT2_ST	Q7Z6J0	SH3RF1	P31751	AKT2	S800	A805T	805	Missense	distal	5	no	29.656	29.332	EPSD	CCLE	19.022	Down-regulation
AGC_Akt_AKT2_ST	Q15118	PDK1	P31751	AKT2	S393	L400I	400	Missense	distal	7	no	21.110	21.331	EPSD	CCLE	19.022	Up-regulation
AGC_Akt_AKT2_ST	P30405	PPIF	P31751	AKT2	S40	S39F	39	Missense	proximal	-1	no	20.686	19.656	EPSD	CCLE	19.022	Down-regulation
AGC_Akt_AKT2_ST	P04406	GAPDH	P31751	AKT2	T211	I207V	207	Missense	distal	-4	no	19.326	19.075	EPSD	CCLE	19.022	Down-regulation
CMGC_DYRK_HIPK_HIPK3_ST	Q9UER7	DAXX	Q9H422	HIPK3	S33	P29L	29	Missense	distal	-4	no	4.350	4.381	EPSD	CCLE	1.096	Up-regulation
CMGC_DYRK_HIPK_HIPK3_ST	Q9UER7	DAXX	Q9H422	HIPK3	S33	P29S	29	Missense	distal	-4	no	4.350	4.424	EPSD	CCLE	1.096	Up-regulation
CMGC_DYRK_HIPK_HIPK3_ST	Q9UER7	DAXX	Q9H422	HIPK3	T578	T578I	578	Missense	central	0	yes	3.923	0.000	EPSD	CCLE	1.096	Loss
CMGC_DYRK_HIPK_HIPK3_ST	Q9UER7	DAXX	Q9H422	HIPK3	T578	A573G	573	Missense	distal	-5	no	3.923	3.942	EPSD	CCLE	1.096	Up-regulation
CMGC_DYRK_HIPK_HIPK3_ST	Q9UER7	DAXX	Q9H422	HIPK3	S682	S683Y	683	Missense	proximal	1	no	0.620	1.493	EPSD	CCLE	1.096	Gain
CMGC_DYRK_HIPK_HIPK3_ST	Q9UER7	DAXX	Q9H422	HIPK3	S688	S683Y	683	Missense	distal	-5	no	4.728	4.672	EPSD	CCLE	1.096	Down-regulation
CMGC_DYRK_HIPK_HIPK3_ST	Q9UER7	DAXX	Q9H422	HIPK3	S702	P701S	701	Missense	proximal	-1	no	4.960	5.032	EPSD	CCLE	1.096	Up-regulation
AGC_PKC_PKCa_PRKCB_ST	P04083	ANXA1	P05771	PRKCB	S244	K250E	250	Missense	distal	6	no	1.681	1.185	EPSD	CCLE	0.942	Down-regulation
AGC_PKC_PKCa_PRKCB_ST	P10636	MAPT	P05771	PRKCB	S171	P170F	170	Missense	proximal	-1	no	2.924	3.133	EPSD	CCLE	0.942	Up-regulation
AGC_PKC_PKCa_PRKCB_ST	P10636	MAPT	P05771	PRKCB	S171	G174A	174	Missense	distal	3	no	2.924	2.973	EPSD	CCLE	0.942	Up-regulation
AGC_PKC_PKCa_PRKCB_ST	P10636	MAPT	P05771	PRKCB	S214	D221Y	221	Missense	distal	7	no	1.656	1.696	EPSD	CCLE	0.942	Up-regulation
AGC_PKC_PKCa_PRKCB_ST	P10636	MAPT	P05771	PRKCB	S400	K405R	405	Missense	distal	5	no	5.186	5.125	EPSD	CCLE	0.942	Down-regulation
AGC_PKC_PKCa_PRKCB_ST	P10636	MAPT	P05771	PRKCB	T403	K405R	405	Missense	proximal	2	no	1.137	2.760	EPSD	CCLE	0.942	Up-regulation
AGC_PKC_PKCa_PRKCB_ST	P10636	MAPT	P05771	PRKCB	S438	V442I	442	Missense	distal	4	no	1.209	1.269	EPSD	CCLE	0.942	Up-regulation
AGC_PKC_PKCa_PRKCB_ST	P10636	MAPT	P05771	PRKCB	S525	G518S	518	Missense	distal	-7	no	1.150	1.069	EPSD	CCLE	0.942	Down-regulation
AGC_PKC_PKCa_PRKCB_ST	P10636	MAPT	P05771	PRKCB	S525	R526L	526	Missense	proximal	1	no	1.150	0.465	EPSD	CCLE	0.942	Loss
AGC_PKC_PKCa_PRKCB_ST	P10636	MAPT	P05771	PRKCB	S531	R526L	526	Missense	distal	-5	no	1.751	1.496	EPSD	CCLE	0.942	Down-regulation
AGC_PKC_PKCa_PRKCB_ST	P10636	MAPT	P05771	PRKCB	S555	R559H	559	Missense	distal	4	no	2.171	1.349	EPSD	CCLE	0.942	Down-regulation
AGC_PKC_PKCa_PRKCB_ST	P10636	MAPT	P05771	PRKCB	S633	D631E	631	Missense	proximal	-2	no	1.139	2.051	EPSD	CCLE	0.942	Up-regulation
AGC_PKC_PKCa_PRKCB_ST	P10636	MAPT	P05771	PRKCB	S637	D631E	631	Missense	distal	-6	no	4.072	4.169	EPSD	CCLE	0.942	Up-regulation
AGC_PKC_PKCa_PRKCB_ST	P10636	MAPT	P05771	PRKCB	S721	S717C	717	Missense	distal	-4	no	2.050	2.232	EPSD	CCLE	0.942	Up-regulation
AGC_PKC_PKCa_PRKCB_ST	P10636	MAPT	P05771	PRKCB	S721	S721C	721	Missense	central	0	yes	2.050	0.000	EPSD	CCLE	0.942	Loss
AGC_PKC_PKCa_PRKCB_ST	P10636	MAPT	P05771	PRKCB	S721	H724R	724	Missense	distal	3	no	2.050	2.855	EPSD	CCLE	0.942	Up-regulation
AGC_PKC_PKCa_PRKCB_ST	P05107	ITGB2	P05771	PRKCB	T118	V117M	117	Missense	proximal	-1	no	4.279	4.339	EPSD	CCLE	0.942	Up-regulation
AGC_PKC_PKCa_PRKCB_ST	P05771	PRKCB	P05771	PRKCB	S111	I106F	106	Missense	distal	-5	no	2.681	2.635	EPSD	CCLE	0.942	Down-regulation
AGC_PKC_PKCa_PRKCB_ST	P05771	PRKCB	P05771	PRKCB	T250	W247R	247	Missense	distal	-3	no	-3.667	1.825	EPSD	CCLE	0.942	Gain
AGC_PKC_PKCa_PRKCB_ST	P29353	SHC1	P05771	PRKCB	S139	T145M	145	Missense	distal	6	no	3.625	3.460	EPSD;PhosphoSitePlus	CCLE	0.942	Down-regulation
AGC_PKC_PKCa_PRKCB_ST	P29353	SHC1	P05771	PRKCB	T206	A202S	202	Missense	distal	-4	no	8.391	8.336	EPSD;PhosphoSitePlus	CCLE	0.942	Down-regulation
AGC_PKC_PKCa_PRKCB_ST	P29353	SHC1	P05771	PRKCB	S213	R214P	214	Missense	proximal	1	no	4.082	2.261	PhosphoSitePlus;EPSD	CCLE	0.942	Down-regulation
AGC_PKC_PKCa_PRKCB_ST	Q03721	KCNC4	P05771	PRKCB	S9	S8P	8	Missense	proximal	-1	no	4.330	4.271	EPSD;PhosphoSitePlus	CCLE	0.942	Down-regulation
AGC_PKC_PKCa_PRKCB_ST	Q03721	KCNC4	P05771	PRKCB	S15	S8P	8	Missense	distal	-7	no	1.298	1.423	EPSD;PhosphoSitePlus	CCLE	0.942	Up-regulation
AGC_PKC_PKCa_PRKCB_ST	P15336	ATF2	P05771	PRKCB	S314	A319D	319	Missense	distal	5	no	1.491	1.581	EPSD	CCLE	0.942	Up-regulation
AGC_PKC_PKCa_PRKCB_ST	P15336	ATF2	P05771	PRKCB	S314	S307L	307	Missense	distal	-7	no	1.491	1.485	EPSD	CCLE	0.942	Down-regulation
AGC_PKC_PKCa_PRKCB_ST	P49841	GSK3B	P05771	PRKCB	S203	K205R	205	Missense	proximal	2	no	2.951	4.575	EPSD	CCLE	0.942	Up-regulation
AGC_PKC_PKCa_PRKCB_ST	P07355	ANXA2	P05771	PRKCB	S234	M240V	240	Missense	distal	6	no	2.916	2.599	EPSD	CCLE	0.942	Down-regulation
AGC_PKC_PKCa_PRKCB_ST	P07355	ANXA2	P05771	PRKCB	S234	S234R	234	Missense	central	0	yes	2.916	0.000	EPSD	CCLE	0.942	Loss
AGC_PKC_PKCa_PRKCB_ST	P07355	ANXA2	P05771	PRKCB	S236	S234R	234	Missense	proximal	-2	no	0.702	2.655	EPSD	CCLE	0.942	Gain
AGC_PKC_PKCa_PRKCB_ST	P07355	ANXA2	P05771	PRKCB	S243	M240V	240	Missense	distal	-3	no	3.897	4.684	EPSD	CCLE	0.942	Up-regulation
AGC_PKC_PKCa_PRKCB_ST	Q96D31	ORAI1	P05771	PRKCB	S25	G20C	20	Missense	distal	-5	no	2.117	2.138	EPSD	CCLE	0.942	Up-regulation
AGC_PKC_PKCa_PRKCB_ST	Q96D31	ORAI1	P05771	PRKCB	S25	R29Q	29	Missense	distal	4	no	2.117	1.497	EPSD	CCLE	0.942	Down-regulation
AGC_PKC_PKCa_PRKCB_ST	Q96D31	ORAI1	P05771	PRKCB	S27	G20C	20	Missense	distal	-7	no	8.853	8.717	PhosphoSitePlus;EPSD	CCLE	0.942	Down-regulation
AGC_PKC_PKCa_PRKCB_ST	Q96D31	ORAI1	P05771	PRKCB	S27	R29Q	29	Missense	proximal	2	no	8.853	2.304	PhosphoSitePlus;EPSD	CCLE	0.942	Down-regulation
AGC_PKC_PKCa_PRKCB_ST	Q96D31	ORAI1	P05771	PRKCB	S27	S34R	34	Missense	distal	7	no	8.853	8.683	PhosphoSitePlus;EPSD	CCLE	0.942	Down-regulation
AGC_PKC_PKCa_PRKCB_ST	Q96D31	ORAI1	P05771	PRKCB	S30	R29Q	29	Missense	proximal	-1	no	8.414	8.229	EPSD;PhosphoSitePlus	CCLE	0.942	Down-regulation
AGC_PKC_PKCa_PRKCB_ST	Q96D31	ORAI1	P05771	PRKCB	S30	S34R	34	Missense	distal	4	no	8.414	9.431	EPSD;PhosphoSitePlus	CCLE	0.942	Up-regulation
AGC_PKC_PKCa_PRKCB_ST	Q96D31	ORAI1	P05771	PRKCB	S30	G35R	35	Missense	distal	5	no	8.414	8.843	EPSD;PhosphoSitePlus	CCLE	0.942	Up-regulation
AGC_PKC_PKCa_PRKCB_ST	Q96D31	ORAI1	P05771	PRKCB	S30	D36N	36	Missense	distal	6	no	8.414	8.681	EPSD;PhosphoSitePlus	CCLE	0.942	Up-regulation
AGC_PKC_PKCa_PRKCB_ST	Q96D31	ORAI1	P05771	PRKCB	S34	R29Q	29	Missense	distal	-5	no	3.160	3.142	EPSD	CCLE	0.942	Down-regulation
AGC_PKC_PKCa_PRKCB_ST	Q96D31	ORAI1	P05771	PRKCB	S34	S34R	34	Missense	central	0	yes	3.160	0.000	EPSD	CCLE	0.942	Loss
AGC_PKC_PKCa_PRKCB_ST	Q96D31	ORAI1	P05771	PRKCB	S34	G35R	35	Missense	proximal	1	no	3.160	5.269	EPSD	CCLE	0.942	Up-regulation
AGC_PKC_PKCa_PRKCB_ST	Q96D31	ORAI1	P05771	PRKCB	S34	D36N	36	Missense	proximal	2	no	3.160	4.526	EPSD	CCLE	0.942	Up-regulation
AGC_PKC_PKCa_PRKCB_ST	Q16625	OCLN	P05771	PRKCB	S321	M323T	323	Missense	proximal	2	no	0.405	2.523	EPSD	CCLE	0.942	Gain
AGC_PKC_PKCa_PRKCB_ST	P35548	MSX2	P05771	PRKCB	S44	E37K	37	Missense	distal	-7	no	1.972	1.768	EPSD	CCLE	0.942	Down-regulation
AGC_PKC_PKCa_PRKCB_ST	O15519	CFLAR	P05771	PRKCB	S193	P197S	197	Missense	distal	4	no	3.351	3.216	PhosphoSitePlus	CCLE	0.942	Down-regulation
AGC_PKC_PKCa_PRKCB_ST	O15519	CFLAR	P05771	PRKCB	S248	K245E	245	Missense	distal	-3	no	1.767	-1.568	EPSD	CCLE	0.942	Loss
AGC_PKC_PKCa_PRKCB_ST	P48736	PIK3CG	P05771	PRKCB	S417	L414F	414	Missense	distal	-3	no	3.333	4.306	EPSD	CCLE	0.942	Up-regulation
AGC_PKC_PKCa_PRKCB_ST	P48736	PIK3CG	P05771	PRKCB	S582	H577Y	577	Missense	distal	-5	no	6.675	6.781	PhosphoSitePlus	CCLE	0.942	Up-regulation
AGC_PKC_PKCa_PRKCB_ST	Q9P2D0	IBTK	P05771	PRKCB	S1200	F1204S	1204	Missense	distal	4	no	4.542	4.692	PhosphoSitePlus;EPSD	CCLE	0.942	Up-regulation
AGC_PKC_PKCa_PRKCB_ST	Q9P2D0	IBTK	P05771	PRKCB	S1203	F1204S	1204	Missense	proximal	1	no	2.615	0.776	EPSD;PhosphoSitePlus	CCLE	0.942	Loss
AGC_PKC_PKCa_PRKCB_ST	P35568	IRS1	P05771	PRKCB	S24	L19R	19	Missense	distal	-5	no	1.120	1.375	EPSD	CCLE	0.942	Up-regulation
AGC_PKC_PKCa_PRKCB_ST	P35568	IRS1	P05771	PRKCB	S268	S273L	273	Missense	distal	5	no	3.296	3.246	EPSD	CCLE	0.942	Down-regulation
AGC_PKC_PKCa_PRKCB_ST	P35568	IRS1	P05771	PRKCB	S272	S273L	273	Missense	proximal	1	no	1.748	3.088	EPSD	CCLE	0.942	Up-regulation
AGC_PKC_PKCa_PRKCB_ST	P35568	IRS1	P05771	PRKCB	S273	S273L	273	Missense	central	0	yes	1.684	0.000	EPSD	CCLE	0.942	Loss
AGC_PKC_PKCa_PRKCB_ST	P35568	IRS1	P05771	PRKCB	S303	R304H	304	Missense	proximal	1	no	4.483	2.777	EPSD	CCLE	0.942	Down-regulation
AGC_PKC_PKCa_PRKCB_ST	P35568	IRS1	P05771	PRKCB	S303	R302Q	302	Missense	proximal	-1	no	4.483	4.298	EPSD	CCLE	0.942	Down-regulation
AGC_PKC_PKCa_PRKCB_ST	P35568	IRS1	P05771	PRKCB	S307	A314D	314	Missense	distal	7	no	4.780	4.567	EPSD	CCLE	0.942	Down-regulation
AGC_PKC_PKCa_PRKCB_ST	P35568	IRS1	P05771	PRKCB	S307	R304H	304	Missense	distal	-3	no	4.780	1.794	EPSD	CCLE	0.942	Down-regulation
AGC_PKC_PKCa_PRKCB_ST	P35568	IRS1	P05771	PRKCB	S307	R302Q	302	Missense	distal	-5	no	4.780	4.763	EPSD	CCLE	0.942	Down-regulation
AGC_PKC_PKCa_PRKCB_ST	P35568	IRS1	P05771	PRKCB	S581	T579I	579	Missense	proximal	-2	no	1.534	1.371	EPSD	CCLE	0.942	Down-regulation
AGC_PKC_PKCa_PRKCB_ST	P35568	IRS1	P05771	PRKCB	S581	V577M	577	Missense	distal	-4	no	1.534	1.610	EPSD	CCLE	0.942	Up-regulation
AGC_PKC_PKCa_PRKCB_ST	P35568	IRS1	P05771	PRKCB	S795	S795Y	795	Missense	central	0	yes	3.003	0.000	EPSD	CCLE	0.942	Loss
AGC_PKC_PKCa_PRKCB_ST	P35568	IRS1	P05771	PRKCB	S795	L791P	791	Missense	distal	-4	no	3.003	3.040	EPSD	CCLE	0.942	Up-regulation
AGC_PKC_PKCa_PRKCB_ST	P35568	IRS1	P05771	PRKCB	S1101	S1105F	1105	Missense	distal	4	no	1.721	1.571	EPSD	CCLE	0.942	Down-regulation
AGC_PKC_PKCa_PRKCB_ST	P35568	IRS1	P05771	PRKCB	S1134	E1136K	1136	Missense	proximal	2	no	-3.449	1.965	EPSD	CCLE	0.942	Gain
AGC_PKC_PKCa_PRKCB_ST	P35568	IRS1	P05771	PRKCB	S1142	E1136K	1136	Missense	distal	-6	no	4.666	4.811	EPSD	CCLE	0.942	Up-regulation
AGC_PKC_PKCa_PRKCB_ST	P35568	IRS1	P05771	PRKCB	S1143	E1136K	1136	Missense	distal	-7	no	1.236	1.032	EPSD	CCLE	0.942	Down-regulation
AGC_PKC_PKCa_PRKCB_ST	Q13131	PRKAA1	P05771	PRKCB	T382	P376Q	376	Missense	distal	-6	no	3.070	3.294	EPSD	CCLE	0.942	Up-regulation
AGC_PKC_PKCa_PRKCB_ST	Q13131	PRKAA1	P05771	PRKCB	S496	S494L	494	Missense	proximal	-2	no	1.295	0.728	PhosphoSitePlus	CCLE	0.942	Loss
AGC_PKC_PKCa_PRKCB_ST	Q13131	PRKAA1	P05771	PRKCB	S496	S494W	494	Missense	proximal	-2	no	1.295	-0.028	PhosphoSitePlus	CCLE	0.942	Loss
AGC_PKC_PKCa_PRKCB_ST	P11171	EPB41	P05771	PRKCB	S188	Q190P	190	Missense	proximal	2	no	1.715	2.431	EPSD	CCLE	0.942	Up-regulation
AGC_PKC_PKCa_PRKCB_ST	P11171	EPB41	P05771	PRKCB	S469	T462N	462	Missense	distal	-7	no	6.823	6.869	EPSD	CCLE	0.942	Up-regulation
AGC_PKC_PKCa_PRKCB_ST	P11171	EPB41	P05771	PRKCB	S555	S555G	555	Missense	central	0	yes	2.845	0.000	EPSD	CCLE	0.942	Loss
AGC_PKC_PKCa_PRKCB_ST	P11171	EPB41	P05771	PRKCB	S560	S555G	555	Missense	distal	-5	no	1.167	1.160	EPSD	CCLE	0.942	Down-regulation
AGC_PKC_PKCa_PRKCB_ST	P11171	EPB41	P05771	PRKCB	T736	N742T	742	Missense	distal	6	no	1.884	1.592	EPSD	CCLE	0.942	Down-regulation
AGC_PKC_PKCa_PRKCB_ST	P11171	EPB41	P05771	PRKCB	T736	A743V	743	Missense	distal	7	no	1.884	1.829	EPSD	CCLE	0.942	Down-regulation
AGC_PKC_PKCa_PRKCB_ST	P11171	EPB41	P05771	PRKCB	T806	Q802L	802	Missense	distal	-4	no	0.842	1.104	EPSD	CCLE	0.942	Gain
AGC_PKC_PKCa_PRKCB_ST	P11171	EPB41	P05771	PRKCB	T806	G810E	810	Missense	distal	4	no	0.842	1.493	EPSD	CCLE	0.942	Gain
AGC_PKC_PKCa_PRKCB_ST	P28329	CHAT	P05771	PRKCB	S464	A471V	471	Missense	distal	7	no	5.753	5.698	EPSD	CCLE	0.942	Down-regulation
AGC_PKC_PKCa_PRKCB_ST	P28329	CHAT	P05771	PRKCB	S465	A471V	471	Missense	distal	6	no	4.475	4.550	EPSD	CCLE	0.942	Up-regulation
AGC_PKC_PKCa_PRKCB_ST	P28329	CHAT	P05771	PRKCB	S558	A557E	557	Missense	proximal	-1	no	6.129	6.384	EPSD	CCLE	0.942	Up-regulation
AGC_PKC_PKCa_PRKCB_ST	P28329	CHAT	P05771	PRKCB	S594	V591L	591	Missense	distal	-3	no	2.132	0.191	EPSD	CCLE	0.942	Loss
AGC_PKC_PKCa_PRKCB_ST	Q12906	ILF3	P05771	PRKCB	S647	R649Q	649	Missense	proximal	2	no	10.233	3.685	PhosphoSitePlus	CCLE	0.942	Down-regulation
AGC_PKC_PKCa_PRKCB_ST	Q12906	ILF3	P05771	PRKCB	S647	R653H	653	Missense	distal	6	no	10.233	9.474	PhosphoSitePlus	CCLE	0.942	Down-regulation
AGC_PKC_PKCa_PRKCB_ST	P30273	FCER1G	P05771	PRKCB	S69	V64A	64	Missense	distal	-5	no	6.023	6.052	PhosphoSitePlus	CCLE	0.942	Up-regulation
AGC_PKC_PKCa_PRKCB_ST	P30273	FCER1G	P05771	PRKCB	S69	T70A	70	Missense	proximal	1	no	6.023	6.469	PhosphoSitePlus	CCLE	0.942	Up-regulation
CAMK_CAMKL_PASK_PASK_ST	Q96RG2	PASK	Q96RG2	PASK	S70	S71F	71	Missense	proximal	1	no	1.929	1.735	EPSD	CCLE	1.643	Down-regulation
CAMK_CAMKL_PASK_PASK_ST	Q96RG2	PASK	Q96RG2	PASK	T512	P506T	506	Missense	distal	-6	no	2.316	2.296	EPSD	CCLE	1.643	Down-regulation
CAMK_CAMKL_PASK_PASK_ST	Q96RG2	PASK	Q96RG2	PASK	T850	V847I	847	Missense	distal	-3	no	2.078	2.121	EPSD	CCLE	1.643	Up-regulation
CAMK_CAMKL_PASK_PASK_ST	P68104	EEF1A1	Q96RG2	PASK	T432	T432L	432	Missense	central	0	yes	4.305	0.000	PhosphoSitePlus	CCLE	1.643	Loss
Other_TOPK_PBK_ST	P81274	GPSM2	Q96KB5	PBK	T457	K456T	456	Missense	proximal	-1	no	5.572	5.427	PhosphoSitePlus	CCLE	2.342	Down-regulation
Other_PEK_PEK_EIF2AK3_ST	P05198	EIF2S1	Q9NZJ5	EIF2AK3	S49	G44D	44	Missense	distal	-5	no	4.319	4.274	PhosphoSitePlus;EPSD	CCLE	0.763	Down-regulation
TKL_RAF_RAF_BRAF_ST	Q92934	BAD	P15056	BRAF	S75	H73Q	73	Missense	proximal	-2	no	4.371	4.110	PhosphoSitePlus;EPSD	CCLE	2.269	Down-regulation
TKL_RAF_RAF_BRAF_ST	Q92934	BAD	P15056	BRAF	S75	R70W	70	Missense	distal	-5	no	4.371	4.307	PhosphoSitePlus;EPSD	CCLE	2.269	Down-regulation
TKL_RAF_RAF_BRAF_ST	Q92934	BAD	P15056	BRAF	T80	H73Q	73	Missense	distal	-7	no	2.363	2.373	EPSD	CCLE	2.269	Up-regulation
TKL_RAF_RAF_BRAF_ST	P68104	EEF1A1	P15056	BRAF	S21	T23A	23	Missense	proximal	2	no	4.317	4.339	EPSD;PhosphoSitePlus	CCLE	2.269	Up-regulation
TKL_RAF_RAF_BRAF_ST	P68104	EEF1A1	P15056	BRAF	S224	G221C	221	Missense	distal	-3	no	2.255	2.286	EPSD	CCLE	2.269	Gain
TKL_RAF_RAF_BRAF_ST	Q9H9S0	NANOG	P15056	BRAF	S57	M58V	58	Missense	proximal	1	no	2.653	2.640	EPSD	CCLE	2.269	Down-regulation
TKL_RAF_RAF_BRAF_ST	P15056	BRAF	P15056	BRAF	S428	R435S	435	Missense	distal	7	no	2.410	2.111	EPSD	CCLE	2.269	Loss
TKL_RAF_RAF_BRAF_ST	P15056	BRAF	P15056	BRAF	T440	R435S	435	Missense	distal	-5	no	2.323	2.389	EPSD	CCLE	2.269	Up-regulation
TKL_RAF_RAF_BRAF_ST	Q05639	EEF1A2	P15056	BRAF	S224	E220K	220	Missense	distal	-4	no	2.268	2.300	EPSD	CCLE	2.269	Gain
TKL_RAF_RAF_BRAF_ST	P33981	TTK	P15056	BRAF	T51	T45N	45	Missense	distal	-6	no	2.107	2.277	EPSD	CCLE	2.269	Gain
Other_NEK_NEK9_NEK9_ST	Q8NHV4	NEDD1	Q8TD19	NEK9	S404	G407S	407	Missense	distal	3	no	3.442	3.445	EPSD	CCLE	2.671	Up-regulation
Other_NEK_NEK9_NEK9_ST	Q8NHV4	NEDD1	Q8TD19	NEK9	S404	S411L	411	Missense	distal	7	no	3.442	3.346	EPSD	CCLE	2.671	Down-regulation
Other_NEK_NEK9_NEK9_ST	Q8TD19	NEK9	Q8TD19	NEK9	S769	S765G	765	Missense	distal	-4	no	4.072	4.114	EPSD	CCLE	2.671	Up-regulation
Other_NEK_NEK9_NEK9_ST	Q8TD19	NEK9	Q8TD19	NEK9	S836	E839K	839	Missense	distal	3	no	3.338	3.339	EPSD	CCLE	2.671	Up-regulation
Other_NEK_NEK9_NEK9_ST	Q8TD19	NEK9	Q8TD19	NEK9	S869	R871Q	871	Missense	proximal	2	no	2.774	2.806	EPSD	CCLE	2.671	Up-regulation
Other_NEK_NEK9_NEK9_ST	Q9HC98	NEK6	Q8TD19	NEK9	T35	T35M	35	Missense	central	0	yes	3.825	0.000	EPSD	CCLE	2.671	Loss
Other_NEK_NEK9_NEK9_ST	Q9HC98	NEK6	Q8TD19	NEK9	S206	H205R	205	Missense	proximal	-1	no	8.354	7.938	PhosphoSitePlus	CCLE	2.671	Down-regulation
Other_NEK_NEK9_NEK9_ST	Q9HC98	NEK6	Q8TD19	NEK9	S206	T210M	210	Missense	distal	4	no	8.354	7.931	PhosphoSitePlus	CCLE	2.671	Down-regulation
AGC_PKC_PKCa_PRKCG_ST	P07900	HSP90AA1	P05129	PRKCG	T115	G108D	108	Missense	distal	-7	no	121.566	123.906	PhosphoSitePlus;EPSD	CCLE	98.543	Up-regulation
AGC_PKC_PKCa_PRKCG_ST	P07900	HSP90AA1	P05129	PRKCG	T171	T171I	171	Missense	central	0	yes	107.466	0.000	EPSD	CCLE	98.543	Loss
AGC_PKC_PKCa_PRKCG_ST	P07900	HSP90AA1	P05129	PRKCG	S406	I408F	408	Missense	proximal	2	no	111.263	114.682	EPSD	CCLE	98.543	Up-regulation
AGC_PKC_PKCa_PRKCG_ST	P07900	HSP90AA1	P05129	PRKCG	S476	D479N	479	Missense	distal	3	no	112.123	119.284	EPSD	CCLE	98.543	Up-regulation
AGC_PKC_PKCa_PRKCG_ST	P07900	HSP90AA1	P05129	PRKCG	T603	Y604F	604	Missense	proximal	1	no	124.768	127.745	EPSD;PhosphoSitePlus	CCLE	98.543	Up-regulation
AGC_PKC_PKCa_PRKCG_ST	P07900	HSP90AA1	P05129	PRKCG	T645	I642T	642	Missense	distal	-3	no	95.739	106.222	EPSD	CCLE	98.543	Gain
AGC_PKC_PKCa_PRKCG_ST	P10636	MAPT	P05129	PRKCG	S531	R526L	526	Missense	distal	-5	no	99.229	102.038	EPSD	CCLE	98.543	Up-regulation
AGC_PKC_PKCa_PRKCG_ST	P10636	MAPT	P05129	PRKCG	S555	R559H	559	Missense	distal	4	no	99.853	94.416	EPSD	CCLE	98.543	Loss
AGC_PKC_PKCa_PRKCG_ST	P10636	MAPT	P05129	PRKCG	T562	R559H	559	Missense	distal	-3	no	112.590	109.831	EPSD	CCLE	98.543	Down-regulation
AGC_PKC_PKCa_PRKCG_ST	P10636	MAPT	P05129	PRKCG	S575	K574N	574	Missense	proximal	-1	no	124.683	123.243	EPSD	CCLE	98.543	Down-regulation
AGC_PKC_PKCa_PRKCG_ST	P10636	MAPT	P05129	PRKCG	S721	S717C	717	Missense	distal	-4	no	100.732	97.819	EPSD	CCLE	98.543	Loss
AGC_PKC_PKCa_PRKCG_ST	P10636	MAPT	P05129	PRKCG	S721	S721C	721	Missense	central	0	yes	100.732	0.000	EPSD	CCLE	98.543	Loss
AGC_PKC_PKCa_PRKCG_ST	P10636	MAPT	P05129	PRKCG	S721	H724R	724	Missense	distal	3	no	100.732	101.081	EPSD	CCLE	98.543	Up-regulation
AGC_PKC_PKCa_PRKCG_ST	P10636	MAPT	P05129	PRKCG	S726	S721C	721	Missense	distal	-5	no	107.088	114.193	EPSD	CCLE	98.543	Up-regulation
AGC_PKC_PKCa_PRKCG_ST	P10636	MAPT	P05129	PRKCG	S726	H724R	724	Missense	proximal	-2	no	107.088	109.815	EPSD	CCLE	98.543	Up-regulation
AGC_PKC_PKCa_PRKCG_ST	P10636	MAPT	P05129	PRKCG	S739	Q741K	741	Missense	proximal	2	no	79.699	105.386	EPSD	CCLE	98.543	Gain
AGC_PKC_PKCa_PRKCG_ST	Q03721	KCNC4	P05129	PRKCG	S8	S8P	8	Missense	central	0	yes	124.337	0.000	PhosphoSitePlus;EPSD	CCLE	98.543	Loss
AGC_PKC_PKCa_PRKCG_ST	Q03721	KCNC4	P05129	PRKCG	S9	S8P	8	Missense	proximal	-1	no	165.875	160.810	EPSD;PhosphoSitePlus	CCLE	98.543	Down-regulation
AGC_PKC_PKCa_PRKCG_ST	Q03721	KCNC4	P05129	PRKCG	S15	S8P	8	Missense	distal	-7	no	135.219	132.937	EPSD;PhosphoSitePlus	CCLE	98.543	Down-regulation
AGC_PKC_PKCa_PRKCG_ST	P50281	MMP14	P05129	PRKCG	T140	E142K	142	Missense	proximal	2	no	73.203	105.155	EPSD	CCLE	98.543	Gain
AGC_PKC_PKCa_PRKCG_ST	Q9UBS0	RPS6KB2	P05129	PRKCG	S15	G19S	19	Missense	distal	4	no	122.067	123.006	EPSD	CCLE	98.543	Up-regulation
AGC_PKC_PKCa_PRKCG_ST	Q9UBS0	RPS6KB2	P05129	PRKCG	S266	Y260H	260	Missense	distal	-6	no	103.558	109.459	EPSD	CCLE	98.543	Up-regulation
AGC_PKC_PKCa_PRKCG_ST	Q14155	ARHGEF7	P05129	PRKCG	S676	K682R	682	Missense	distal	6	no	102.368	100.681	EPSD	CCLE	98.543	Down-regulation
AGC_PKC_PKCa_PRKCG_ST	Q14155	ARHGEF7	P05129	PRKCG	T679	K682R	682	Missense	distal	3	no	105.583	104.929	EPSD	CCLE	98.543	Down-regulation
AGC_PKC_PKCa_PRKCG_ST	Q7Z2E3	APTX	P05129	PRKCG	S177	A171E	171	Missense	distal	-6	no	98.621	94.741	EPSD	CCLE	98.543	Loss
AGC_PKC_PKCa_PRKCG_ST	P28329	CHAT	P05129	PRKCG	S464	A471V	471	Missense	distal	7	no	131.934	124.889	EPSD	CCLE	98.543	Down-regulation
AGC_PKC_PKCa_PRKCG_ST	P28329	CHAT	P05129	PRKCG	S465	A471V	471	Missense	distal	6	no	123.224	122.744	EPSD	CCLE	98.543	Down-regulation
AGC_PKC_PKCa_PRKCG_ST	P28329	CHAT	P05129	PRKCG	S558	A557E	557	Missense	proximal	-1	no	134.661	134.066	EPSD	CCLE	98.543	Down-regulation
AGC_PKC_PKCa_PRKCG_ST	P28329	CHAT	P05129	PRKCG	S594	V591L	591	Missense	distal	-3	no	127.395	129.692	EPSD	CCLE	98.543	Up-regulation
AGC_PKC_PKCa_PRKCG_ST	P08138	NGFR	P05129	PRKCG	S277	K282Q	282	Missense	distal	5	no	131.284	131.769	PhosphoSitePlus	CCLE	98.543	Up-regulation
AGC_PKC_PKCa_PRKCG_ST	P08138	NGFR	P05129	PRKCG	S287	K282Q	282	Missense	distal	-5	no	98.199	99.180	EPSD	CCLE	98.543	Gain
TK_PDGFR_FLT3_Y	P36888	FLT3	P36888	FLT3	Y726	H732Y	732	Missense	distal	6	no	1.198	1.179	EPSD;PhosphoSitePlus	CCLE	0.779	Down-regulation
TK_PDGFR_FLT3_Y	P36888	FLT3	P36888	FLT3	Y793	A792S	792	Missense	proximal	-1	no	0.779	0.786	EPSD	CCLE	0.779	Up-regulation
TK_PDGFR_FLT3_Y	P36888	FLT3	P36888	FLT3	Y842	R849C	849	Missense	distal	7	no	1.234	1.223	EPSD;PhosphoSitePlus	CCLE	0.779	Down-regulation
TK_PDGFR_FLT3_Y	P36888	FLT3	P36888	FLT3	Y955	V958M	958	Missense	distal	3	no	1.584	1.583	PhosphoSitePlus;EPSD	CCLE	0.779	Down-regulation
TK_PDGFR_FLT3_Y	P36888	FLT3	P36888	FLT3	Y969	E964G	964	Missense	distal	-5	no	1.490	1.400	EPSD;PhosphoSitePlus	CCLE	0.779	Down-regulation
TK_PDGFR_FLT3_Y	Q15118	PDK1	P36888	FLT3	Y243	Y243H	243	Missense	central	0	yes	1.394	0.000	PhosphoSitePlus	CCLE	0.779	Loss
TK_PDGFR_FLT3_Y	Q15118	PDK1	P36888	FLT3	Y243	N246H	246	Missense	distal	3	no	1.394	1.372	PhosphoSitePlus	CCLE	0.779	Down-regulation
CMGC_SRPK_SRPK1_ST	Q96SB4	SRPK1	Q96SB4	SRPK1	S249	G242I	242	Missense	distal	-7	no	57.729	54.953	EPSD	CCLE	48.822	Down-regulation
CMGC_SRPK_SRPK1_ST	Q07955	SRSF1	Q96SB4	SRPK1	S91	R90G	90	Missense	proximal	-1	no	55.432	27.703	EPSD	CCLE	48.822	Loss
CMGC_SRPK_SRPK1_ST	Q07955	SRSF1	Q96SB4	SRPK1	S119	V125F	125	Missense	distal	6	no	68.718	71.057	EPSD	CCLE	48.822	Up-regulation
CMGC_SRPK_SRPK1_ST	Q07955	SRSF1	Q96SB4	SRPK1	S131	V125F	125	Missense	distal	-6	no	50.381	51.687	EPSD	CCLE	48.822	Up-regulation
CMGC_SRPK_SRPK1_ST	Q07955	SRSF1	Q96SB4	SRPK1	S223	R229M	229	Missense	distal	6	no	233.506	225.989	EPSD;PhosphoSitePlus	CCLE	48.822	Down-regulation
CMGC_SRPK_SRPK1_ST	Q07955	SRSF1	Q96SB4	SRPK1	S225	R229M	229	Missense	distal	4	no	256.763	252.351	EPSD;PhosphoSitePlus	CCLE	48.822	Down-regulation
CMGC_SRPK_SRPK1_ST	Q07955	SRSF1	Q96SB4	SRPK1	S227	R229M	229	Missense	proximal	2	no	221.842	217.742	EPSD;PhosphoSitePlus	CCLE	48.822	Down-regulation
CMGC_SRPK_SRPK1_ST	Q07955	SRSF1	Q96SB4	SRPK1	S231	R229M	229	Missense	proximal	-2	no	185.483	180.547	EPSD	CCLE	48.822	Down-regulation
CMGC_SRPK_SRPK1_ST	Q07955	SRSF1	Q96SB4	SRPK1	S234	R229M	229	Missense	distal	-5	no	75.861	64.699	EPSD	CCLE	48.822	Down-regulation
AGC_PKC_PKCi_PRKCZ_ST	Q9Y6Q9	NCOA3	Q05513	PRKCZ	S563	Q565H	565	Missense	proximal	2	no	32.930	36.645	EPSD	CCLE	31.494	Up-regulation
AGC_PKC_PKCi_PRKCZ_ST	Q9Y6Q9	NCOA3	Q05513	PRKCZ	S778	E780Q	780	Missense	proximal	2	no	27.908	32.188	EPSD	CCLE	31.494	Gain
AGC_PKC_PKCi_PRKCZ_ST	Q16625	OCLN	Q05513	PRKCZ	S321	M323T	323	Missense	proximal	2	no	42.426	40.259	EPSD	CCLE	31.494	Down-regulation
AGC_PKC_PKCi_PRKCZ_ST	Q16625	OCLN	Q05513	PRKCZ	S369	Q365K	365	Missense	distal	-4	no	32.247	32.162	EPSD	CCLE	31.494	Down-regulation
AGC_PKC_PKCi_PRKCZ_ST	Q16625	OCLN	Q05513	PRKCZ	S458	R459C	459	Missense	proximal	1	no	40.410	38.094	EPSD	CCLE	31.494	Down-regulation
AGC_PKC_PKCi_PRKCZ_ST	P10636	MAPT	Q05513	PRKCZ	S171	P170F	170	Missense	proximal	-1	no	39.858	40.032	EPSD	CCLE	31.494	Up-regulation
AGC_PKC_PKCi_PRKCZ_ST	P10636	MAPT	Q05513	PRKCZ	S171	G174A	174	Missense	distal	3	no	39.858	40.387	EPSD	CCLE	31.494	Up-regulation
AGC_PKC_PKCi_PRKCZ_ST	P10636	MAPT	Q05513	PRKCZ	S238	D242H	242	Missense	distal	4	no	29.331	31.912	EPSD	CCLE	31.494	Gain
AGC_PKC_PKCi_PRKCZ_ST	P10636	MAPT	Q05513	PRKCZ	S400	K405R	405	Missense	distal	5	no	38.197	38.562	EPSD	CCLE	31.494	Up-regulation
AGC_PKC_PKCi_PRKCZ_ST	P10636	MAPT	Q05513	PRKCZ	S447	V442I	442	Missense	distal	-5	no	43.476	41.312	EPSD	CCLE	31.494	Down-regulation
AGC_PKC_PKCi_PRKCZ_ST	P10636	MAPT	Q05513	PRKCZ	S554	R559H	559	Missense	distal	5	no	36.742	36.334	EPSD	CCLE	31.494	Down-regulation
AGC_PKC_PKCi_PRKCZ_ST	P10636	MAPT	Q05513	PRKCZ	S633	D631E	631	Missense	proximal	-2	no	31.601	23.194	EPSD	CCLE	31.494	Loss
AGC_PKC_PKCi_PRKCZ_ST	P10636	MAPT	Q05513	PRKCZ	T703	G706V	706	Missense	distal	3	no	38.159	29.295	EPSD	CCLE	31.494	Loss
AGC_PKC_PKCi_PRKCZ_ST	P10636	MAPT	Q05513	PRKCZ	S726	H724R	724	Missense	proximal	-2	no	25.799	34.652	EPSD	CCLE	31.494	Gain
AGC_PKC_PKCi_PRKCZ_ST	P10636	MAPT	Q05513	PRKCZ	S739	Q741K	741	Missense	proximal	2	no	29.539	34.866	EPSD	CCLE	31.494	Gain
AGC_PKC_PKCi_PRKCZ_ST	P10636	MAPT	Q05513	PRKCZ	T744	Q741K	741	Missense	distal	-3	no	31.521	38.270	EPSD	CCLE	31.494	Up-regulation
AGC_PKC_PKCi_PRKCZ_ST	O43175	PHGDH	Q05513	PRKCZ	S166	M169T	169	Missense	distal	3	no	34.088	31.996	EPSD	CCLE	31.494	Down-regulation
AGC_PKC_PKCi_PRKCZ_ST	P53004	BLVRA	Q05513	PRKCZ	S21	R18Q	18	Missense	distal	-3	no	38.923	27.036	EPSD	CCLE	31.494	Loss
AGC_PKC_PKCi_PRKCZ_ST	Q13118	KLF10	Q05513	PRKCZ	S384	R391G	391	Missense	distal	7	no	39.136	41.449	PhosphoSitePlus;EPSD	CCLE	31.494	Up-regulation
AGC_PKC_PKCi_PRKCZ_ST	Q13118	KLF10	Q05513	PRKCZ	T394	R391G	391	Missense	distal	-3	no	34.257	20.019	EPSD	CCLE	31.494	Loss
AGC_PKC_PKCi_PRKCZ_ST	P49841	GSK3B	Q05513	PRKCZ	S147	T152M	152	Missense	distal	5	no	42.594	42.848	PhosphoSitePlus;EPSD	CCLE	31.494	Up-regulation
AGC_PKC_PKCi_PRKCZ_ST	P49841	GSK3B	Q05513	PRKCZ	S203	K205R	205	Missense	proximal	2	no	32.200	34.742	EPSD	CCLE	31.494	Up-regulation
AGC_PKC_PKCi_PRKCZ_ST	Q15831	STK11	Q05513	PRKCZ	S404	A398T	398	Missense	distal	-6	no	33.539	33.686	EPSD	CCLE	31.494	Up-regulation
AGC_PKC_PKCi_PRKCZ_ST	Q15831	STK11	Q05513	PRKCZ	S404	A398G	398	Missense	distal	-6	no	33.539	33.769	EPSD	CCLE	31.494	Up-regulation
AGC_PKC_PKCi_PRKCZ_ST	Q15831	STK11	Q05513	PRKCZ	S404	E407D	407	Missense	distal	3	no	33.539	38.674	EPSD	CCLE	31.494	Up-regulation
AGC_PKC_PKCi_PRKCZ_ST	P35580	MYH10	Q05513	PRKCZ	S1699	R1704Q	1704	Missense	distal	5	no	36.838	36.211	EPSD	CCLE	31.494	Down-regulation
AGC_PKC_PKCi_PRKCZ_ST	P08047	SP1	Q05513	PRKCZ	S41	G44S	44	Missense	distal	3	no	37.171	31.196	EPSD	CCLE	31.494	Loss
AGC_PKC_PKCi_PRKCZ_ST	P08047	SP1	Q05513	PRKCZ	S698	R694C	694	Missense	distal	-4	no	32.339	33.002	EPSD	CCLE	31.494	Up-regulation
AGC_PKC_PKCi_PRKCZ_ST	P27448	MARK3	Q05513	PRKCZ	S419	R417C	417	Missense	proximal	-2	no	44.793	31.002	EPSD	CCLE	31.494	Loss
AGC_PKC_PKCi_PRKCZ_ST	P27448	MARK3	Q05513	PRKCZ	T438	P433A	433	Missense	distal	-5	no	39.089	36.362	EPSD	CCLE	31.494	Down-regulation
AGC_PKC_PKCi_PRKCZ_ST	P27448	MARK3	Q05513	PRKCZ	T438	P433L	433	Missense	distal	-5	no	39.089	39.212	EPSD	CCLE	31.494	Up-regulation
AGC_PKC_PKCi_PRKCZ_ST	P27448	MARK3	Q05513	PRKCZ	S734	R732W	732	Missense	proximal	-2	no	44.141	25.968	EPSD	CCLE	31.494	Loss
AGC_PKC_PKCi_PRKCZ_ST	Q96RI1	NR1H4	Q05513	PRKCZ	S467	S467P	467	Missense	central	0	yes	45.617	0.000	EPSD	CCLE	31.494	Loss
AGC_PKC_PKCi_PRKCZ_ST	P35568	IRS1	Q05513	PRKCZ	S24	L19R	19	Missense	distal	-5	no	37.310	33.757	EPSD	CCLE	31.494	Down-regulation
AGC_PKC_PKCi_PRKCZ_ST	P35568	IRS1	Q05513	PRKCZ	S268	S273L	273	Missense	distal	5	no	36.016	35.950	EPSD	CCLE	31.494	Down-regulation
AGC_PKC_PKCi_PRKCZ_ST	P35568	IRS1	Q05513	PRKCZ	S303	R304H	304	Missense	proximal	1	no	39.220	38.045	EPSD	CCLE	31.494	Down-regulation
AGC_PKC_PKCi_PRKCZ_ST	P35568	IRS1	Q05513	PRKCZ	S303	R302Q	302	Missense	proximal	-1	no	39.220	38.058	EPSD	CCLE	31.494	Down-regulation
AGC_PKC_PKCi_PRKCZ_ST	P35568	IRS1	Q05513	PRKCZ	S307	A314D	314	Missense	distal	7	no	35.352	36.641	EPSD	CCLE	31.494	Up-regulation
AGC_PKC_PKCi_PRKCZ_ST	P35568	IRS1	Q05513	PRKCZ	S307	R304H	304	Missense	distal	-3	no	35.352	26.923	EPSD	CCLE	31.494	Loss
AGC_PKC_PKCi_PRKCZ_ST	P35568	IRS1	Q05513	PRKCZ	S307	R302Q	302	Missense	distal	-5	no	35.352	37.763	EPSD	CCLE	31.494	Up-regulation
AGC_PKC_PKCi_PRKCZ_ST	P35568	IRS1	Q05513	PRKCZ	T525	P532S	532	Missense	distal	7	no	32.377	29.068	EPSD	CCLE	31.494	Loss
AGC_PKC_PKCi_PRKCZ_ST	P35568	IRS1	Q05513	PRKCZ	S574	T579I	579	Missense	distal	5	no	33.848	34.063	EPSD	CCLE	31.494	Up-regulation
AGC_PKC_PKCi_PRKCZ_ST	P35568	IRS1	Q05513	PRKCZ	S574	V577M	577	Missense	distal	3	no	33.848	39.123	EPSD	CCLE	31.494	Up-regulation
AGC_PKC_PKCi_PRKCZ_ST	P35568	IRS1	Q05513	PRKCZ	S1037	A1032T	1032	Missense	distal	-5	no	31.965	33.307	EPSD	CCLE	31.494	Up-regulation
AGC_PKC_PKCi_PRKCZ_ST	P35568	IRS1	Q05513	PRKCZ	S1037	M1031T	1031	Missense	distal	-6	no	31.965	32.005	EPSD	CCLE	31.494	Up-regulation
AGC_PKC_PKCi_PRKCZ_ST	P35568	IRS1	Q05513	PRKCZ	S1100	S1105F	1105	Missense	distal	5	no	34.706	34.526	EPSD	CCLE	31.494	Down-regulation
AGC_PKC_PKCi_PRKCZ_ST	P35568	IRS1	Q05513	PRKCZ	S1142	E1136K	1136	Missense	distal	-6	no	38.241	37.798	EPSD	CCLE	31.494	Down-regulation
AGC_PKC_PKCi_PRKCZ_ST	P35568	IRS1	Q05513	PRKCZ	S1143	E1136K	1136	Missense	distal	-7	no	38.195	44.015	EPSD	CCLE	31.494	Up-regulation
AGC_PKC_PKCi_PRKCZ_ST	P35611	ADD1	Q05513	PRKCZ	S669	A664V	664	Missense	distal	-5	no	29.268	31.856	EPSD	CCLE	31.494	Gain
AGC_PKC_PKCi_PRKCZ_ST	Q9UJZ1	STOML2	Q05513	PRKCZ	S17	S17F	17	Missense	central	0	yes	43.322	0.000	PhosphoSitePlus	CCLE	31.494	Loss
AGC_PKC_PKCi_PRKCZ_ST	Q9UJZ1	STOML2	Q05513	PRKCZ	S21	S17F	17	Missense	distal	-4	no	37.672	37.784	EPSD	CCLE	31.494	Up-regulation
AGC_PKC_PKCi_PRKCZ_ST	Q9UJZ1	STOML2	Q05513	PRKCZ	S345	G341D	341	Missense	distal	-4	no	39.022	39.162	EPSD	CCLE	31.494	Up-regulation
AGC_PKC_PKCi_PRKCZ_ST	P78563	ADARB1	Q05513	PRKCZ	S13	E6K	6	Missense	distal	-7	no	30.304	36.124	EPSD	CCLE	31.494	Gain
AGC_PKC_PKCi_PRKCZ_ST	Q9UIQ6	LNPEP	Q05513	PRKCZ	S666	S670L	670	Missense	distal	4	no	43.902	33.079	EPSD	CCLE	31.494	Down-regulation
AGC_PKC_PKCi_PRKCZ_ST	Q15466	NR0B2	Q05513	PRKCZ	T55	R57W	57	Missense	proximal	2	no	32.103	17.766	PhosphoSitePlus	CCLE	31.494	Loss
AGC_PKC_PKCi_PRKCZ_ST	Q15466	NR0B2	Q05513	PRKCZ	T55	T55A	55	Missense	central	0	yes	32.103	0.000	PhosphoSitePlus	CCLE	31.494	Loss
AGC_PKC_PKCi_PRKCZ_ST	P28329	CHAT	Q05513	PRKCZ	T25	V31G	31	Missense	distal	6	no	43.692	42.967	EPSD	CCLE	31.494	Down-regulation
AGC_PKC_PKCi_PRKCZ_ST	P28329	CHAT	Q05513	PRKCZ	S465	A471V	471	Missense	distal	6	no	35.215	33.295	EPSD	CCLE	31.494	Down-regulation
AGC_PKC_PKCi_PRKCZ_ST	P46937	YAP1	Q05513	PRKCZ	T428	D421N	421	Missense	distal	-7	no	34.511	31.700	EPSD	CCLE	31.494	Down-regulation
AGC_PKC_PKCi_PRKCZ_ST	Q16612	NREP	Q05513	PRKCZ	S59	R58H	58	Missense	proximal	-1	no	36.358	35.559	PhosphoSitePlus	CCLE	31.494	Down-regulation
AGC_PKC_PKCi_PRKCZ_ST	Q16612	NREP	Q05513	PRKCZ	S59	R58S	58	Missense	proximal	-1	no	36.358	35.256	PhosphoSitePlus	CCLE	31.494	Down-regulation
AGC_PKC_PKCi_PRKCZ_ST	P55040	GEM	Q05513	PRKCZ	S261	K265T	265	Missense	distal	4	no	45.568	41.813	PhosphoSitePlus	CCLE	31.494	Down-regulation
AGC_PKC_PKCi_PRKCZ_ST	P55040	GEM	Q05513	PRKCZ	S287	S294P	294	Missense	distal	7	no	32.483	35.792	EPSD	CCLE	31.494	Up-regulation
AGC_PKC_PKCi_PRKCZ_ST	P55040	GEM	Q05513	PRKCZ	S289	S294P	294	Missense	distal	5	no	41.537	41.558	EPSD	CCLE	31.494	Up-regulation
AGC_PKC_PKCi_PRKCZ_ST	Q12933	TRAF2	Q05513	PRKCZ	S55	Y53C	53	Missense	proximal	-2	no	34.062	31.892	PhosphoSitePlus	CCLE	31.494	Down-regulation
AGC_PKC_PKCi_PRKCZ_ST	P14598	NCF1	Q05513	PRKCZ	S320	R326H	326	Missense	distal	6	no	55.231	54.188	EPSD	CCLE	31.494	Down-regulation
AGC_PKC_PKCi_PRKCZ_ST	P14598	NCF1	Q05513	PRKCZ	S328	R326H	326	Missense	proximal	-2	no	37.308	28.455	EPSD	CCLE	31.494	Loss
AGC_PKC_PKCi_PRKCZ_ST	P14598	NCF1	Q05513	PRKCZ	T356	R354L	354	Missense	proximal	-2	no	32.913	21.353	EPSD	CCLE	31.494	Loss
AGC_PKC_PKCi_PRKCZ_ST	P14598	NCF1	Q05513	PRKCZ	T356	Q357H	357	Missense	proximal	1	no	32.913	34.011	EPSD	CCLE	31.494	Up-regulation
AGC_PKC_PKCi_PRKCZ_ST	Q04206	RELA	Q05513	PRKCZ	S468	A467V	467	Missense	proximal	-1	no	33.736	32.811	EPSD	CCLE	31.494	Down-regulation
AGC_PKC_PKCi_PRKCZ_ST	Q04206	RELA	Q05513	PRKCZ	T505	L503P	503	Missense	proximal	-2	no	44.864	42.486	EPSD	CCLE	31.494	Down-regulation
AGC_PKC_PKCi_PRKCZ_ST	Q04206	RELA	Q05513	PRKCZ	S536	S535A	535	Missense	proximal	-1	no	42.930	43.622	EPSD	CCLE	31.494	Up-regulation
Other_PLK_PLK2_PLK3_ST	P15336	ATF2	Q9H4B4	PLK3	T69	R74K	74	Missense	distal	5	no	16.687	16.366	PhosphoSitePlus;EPSD	CCLE	8.404	Down-regulation
Other_PLK_PLK2_PLK3_ST	P15336	ATF2	Q9H4B4	PLK3	T71	R74K	74	Missense	distal	3	no	15.978	17.380	EPSD;PhosphoSitePlus	CCLE	8.404	Up-regulation
Other_PLK_PLK2_PLK3_ST	P15336	ATF2	Q9H4B4	PLK3	S310	S307L	307	Missense	distal	-3	no	9.437	10.539	EPSD	CCLE	8.404	Up-regulation
Other_PLK_PLK2_PLK3_ST	P15336	ATF2	Q9H4B4	PLK3	T322	A319D	319	Missense	distal	-3	no	8.380	9.781	EPSD	CCLE	8.404	Gain
Other_PLK_PLK2_PLK3_ST	P15336	ATF2	Q9H4B4	PLK3	T336	A330G	330	Missense	distal	-6	no	8.857	7.516	EPSD	CCLE	8.404	Loss
Other_PLK_PLK2_PLK3_ST	O96017	CHEK2	Q9H4B4	PLK3	T225	L226V	226	Missense	proximal	1	no	9.976	9.159	EPSD	CCLE	8.404	Down-regulation
Other_PLK_PLK2_PLK3_ST	O96017	CHEK2	Q9H4B4	PLK3	S357	D361G	361	Missense	distal	4	no	9.449	9.827	EPSD	CCLE	8.404	Up-regulation
Other_PLK_PLK2_PLK3_ST	O96017	CHEK2	Q9H4B4	PLK3	T441	S435L	435	Missense	distal	-6	no	9.441	6.618	EPSD	CCLE	8.404	Loss
Other_PLK_PLK2_PLK3_ST	P11388	TOP2A	Q9H4B4	PLK3	S387	P385A	385	Missense	proximal	-2	no	8.839	9.464	EPSD	CCLE	8.404	Up-regulation
Other_PLK_PLK2_PLK3_ST	P11388	TOP2A	Q9H4B4	PLK3	S812	R815Q	815	Missense	distal	3	no	9.560	10.749	EPSD	CCLE	8.404	Up-regulation
Other_PLK_PLK2_PLK3_ST	P11388	TOP2A	Q9H4B4	PLK3	S1162	T1157I	1157	Missense	distal	-5	no	7.919	8.440	EPSD	CCLE	8.404	Gain
Other_PLK_PLK2_PLK3_ST	P11388	TOP2A	Q9H4B4	PLK3	S1393	P1394R	1394	Missense	proximal	1	no	9.666	8.913	EPSD	CCLE	8.404	Down-regulation
Other_PLK_PLK2_PLK3_ST	P11388	TOP2A	Q9H4B4	PLK3	S1504	H1499Y	1499	Missense	distal	-5	no	8.471	7.443	EPSD	CCLE	8.404	Loss
Other_PLK_PLK2_PLK3_ST	P60484	PTEN	Q9H4B4	PLK3	S294	D301N	301	Missense	distal	7	no	11.776	11.366	EPSD	CCLE	8.404	Down-regulation
Other_PLK_PLK2_PLK3_ST	O43852	CALU	Q9H4B4	PLK3	S35	V38F	38	Missense	distal	3	no	10.177	9.712	EPSD	CCLE	8.404	Down-regulation
Other_PLK_PLK2_PLK3_ST	O43852	CALU	Q9H4B4	PLK3	S44	V38F	38	Missense	distal	-6	no	16.153	14.941	PhosphoSitePlus;EPSD	CCLE	8.404	Down-regulation
Other_PLK_PLK2_PLK3_ST	P08238	HSP90AB1	Q9H4B4	PLK3	S63	D66E	66	Missense	distal	3	no	9.180	10.236	EPSD	CCLE	8.404	Up-regulation
Other_PLK_PLK2_PLK3_ST	P08238	HSP90AB1	Q9H4B4	PLK3	S164	S160T	160	Missense	distal	-4	no	8.346	8.601	EPSD	CCLE	8.404	Gain
Other_PLK_PLK2_PLK3_ST	P08238	HSP90AB1	Q9H4B4	PLK3	S434	F433L	433	Missense	proximal	-1	no	12.129	11.659	EPSD	CCLE	8.404	Down-regulation
Other_PLK_PLK2_PLK3_ST	P08238	HSP90AB1	Q9H4B4	PLK3	S718	R719G	719	Missense	proximal	1	no	9.874	10.218	PhosphoSitePlus	CCLE	8.404	Up-regulation
Other_PLK_PLK2_PLK3_ST	P06748	NPM1	Q9H4B4	PLK3	S139	K141R	141	Missense	proximal	2	no	10.224	8.971	EPSD	CCLE	8.404	Down-regulation
Other_PLK_PLK2_PLK3_ST	P06748	NPM1	Q9H4B4	PLK3	S143	K141R	141	Missense	proximal	-2	no	9.238	7.119	EPSD	CCLE	8.404	Loss
Other_PLK_PLK2_PLK3_ST	P30307	CDC25C	Q9H4B4	PLK3	S191	S198A	198	Missense	distal	7	no	18.165	17.980	EPSD;PhosphoSitePlus	CCLE	8.404	Down-regulation
Other_PLK_PLK2_PLK3_ST	P30307	CDC25C	Q9H4B4	PLK3	S198	S198A	198	Missense	central	0	yes	14.670	0.000	PhosphoSitePlus;EPSD	CCLE	8.404	Loss
Other_PLK_PLK2_PLK3_ST	P14635	CCNB1	Q9H4B4	PLK3	S116	K114N	114	Missense	proximal	-2	no	8.529	7.517	EPSD	CCLE	8.404	Loss
Other_PLK_PLK2_PLK3_ST	Q14790	CASP8	Q9H4B4	PLK3	S305	M307V	307	Missense	proximal	2	no	10.915	9.739	EPSD	CCLE	8.404	Down-regulation
Other_PLK_PLK2_PLK3_ST	Q99986	VRK1	Q9H4B4	PLK3	S342	G337D	337	Missense	distal	-5	no	16.360	15.320	PhosphoSitePlus	CCLE	8.404	Down-regulation
Other_PLK_PLK2_PLK3_ST	P30304	CDC25A	Q9H4B4	PLK3	S513	R506W	506	Missense	distal	-7	no	10.260	10.878	EPSD	CCLE	8.404	Up-regulation
Other_PLK_PLK2_PLK3_ST	Q16625	OCLN	Q9H4B4	PLK3	S458	R459C	459	Missense	proximal	1	no	8.540	8.929	EPSD	CCLE	8.404	Up-regulation
Other_PLK_PLK2_PLK3_ST	Q16143	SNCB	Q9H4B4	PLK3	S118	P123S	123	Missense	distal	5	no	12.203	12.242	PhosphoSitePlus	CCLE	8.404	Up-regulation
Other_PLK_PLK2_PLK3_ST	Q07817	BCL2L1	Q9H4B4	PLK3	S49	E42D	42	Missense	distal	-7	no	16.063	16.296	PhosphoSitePlus	CCLE	8.404	Up-regulation
CMGC_MAPK_JNK_MAPK10_ST	P01106	MYC	P53779	MAPK10	S73	Y74S	74	Missense	proximal	1	no	0.001	-0.003	EPSD	CCLE	0.000	Loss
CMGC_MAPK_JNK_MAPK10_ST	P01106	MYC	P53779	MAPK10	T78	T78R	78	Missense	central	0	yes	0.023	0.000	EPSD	CCLE	0.000	Loss
CMGC_MAPK_JNK_MAPK10_ST	P01106	MYC	P53779	MAPK10	S81	L82F	82	Missense	proximal	1	no	-0.002	0.000	EPSD	CCLE	0.000	Gain
CMGC_MAPK_JNK_MAPK10_ST	P54259	ATN1	P53779	MAPK10	S79	E80K	80	Missense	proximal	1	no	-0.001	0.000	EPSD	CCLE	0.000	Gain
CMGC_MAPK_JNK_MAPK10_ST	P54259	ATN1	P53779	MAPK10	S632	P633Q	633	Missense	proximal	1	no	0.023	-0.001	EPSD	CCLE	0.000	Loss
CMGC_MAPK_JNK_MAPK10_ST	P55957	BID	P53779	MAPK10	S161	P164L	164	Missense	distal	3	no	-0.001	0.000	EPSD	CCLE	0.000	Gain
CMGC_MAPK_JNK_MAPK10_ST	O95644	NFATC1	P53779	MAPK10	S117	T123N	123	Missense	distal	6	no	0.024	0.023	EPSD	CCLE	0.000	Down-regulation
CMGC_MAPK_JNK_MAPK10_ST	O95644	NFATC1	P53779	MAPK10	S178	S179P	179	Missense	proximal	1	no	-0.003	0.023	EPSD	CCLE	0.000	Gain
CMGC_MAPK_JNK_MAPK10_ST	O95644	NFATC1	P53779	MAPK10	S286	P287S	287	Missense	proximal	1	no	0.023	-0.003	EPSD	CCLE	0.000	Loss
CMGC_MAPK_JNK_MAPK10_ST	O95644	NFATC1	P53779	MAPK10	S406	Y407C	407	Missense	proximal	1	no	0.001	0.000	EPSD	CCLE	0.000	Down-regulation
CMGC_MAPK_JNK_MAPK10_ST	O95644	NFATC1	P53779	MAPK10	S447	R448W	448	Missense	proximal	1	no	-0.001	0.000	EPSD	CCLE	0.000	Gain
Other_NEK_NEK1_NEK1_ST	P40337	VHL	Q96PY6	NEK1	S168	E173D	173	Missense	distal	5	no	4.486	4.503	EPSD;PhosphoSitePlus	CCLE	2.106	Up-regulation
Other_NEK_NEK1_NEK1_ST	O14777	NDC80	Q96PY6	NEK1	S165	S167R	167	Missense	proximal	2	no	4.395	4.480	PhosphoSitePlus	CCLE	2.106	Up-regulation
TK_Axl_AXL_Y	P07948	LYN	P30530	AXL	Y397	Y397C	397	Missense	central	0	yes	0.011	0.000	PhosphoSitePlus	CCLE	0.002	Loss
TK_Axl_AXL_Y	P07948	LYN	P30530	AXL	Y397	A403V	403	Missense	distal	6	no	0.011	0.012	PhosphoSitePlus	CCLE	0.002	Up-regulation
TK_Axl_AXL_Y	P12931	SRC	P30530	AXL	Y439	T432M	432	Missense	distal	-7	no	0.002	0.001	EPSD	CCLE	0.002	Loss
TK_Axl_AXL_Y	P07947	YES1	P30530	AXL	Y100	I95V	95	Missense	distal	-5	no	0.002	0.001	EPSD	CCLE	0.002	Loss
CAMK_DAPK_DAPK_DAPK3_ST	O43293	DAPK3	O43293	DAPK3	T299	R294L	294	Missense	distal	-5	no	12.364	9.522	EPSD;PhosphoSitePlus	CCLE	6.449	Down-regulation
CAMK_DAPK_DAPK_DAPK3_ST	O43293	DAPK3	O43293	DAPK3	T300	R294L	294	Missense	distal	-6	no	6.277	7.295	EPSD	CCLE	6.449	Gain
CAMK_DAPK_DAPK_DAPK3_ST	O43293	DAPK3	O43293	DAPK3	S414	E417D	417	Missense	distal	3	no	6.695	6.721	EPSD	CCLE	6.449	Up-regulation
CAMK_DAPK_DAPK_DAPK3_ST	O43293	DAPK3	O43293	DAPK3	S414	R412C	412	Missense	proximal	-2	no	6.695	4.232	EPSD	CCLE	6.449	Loss
CAMK_DAPK_DAPK_DAPK3_ST	Q00987	MDM2	O43293	DAPK3	T47	D46N	46	Missense	proximal	-1	no	6.776	6.656	EPSD	CCLE	6.449	Down-regulation
CAMK_DAPK_DAPK_DAPK3_ST	P40429	RPL13A	O43293	DAPK3	T64	N63S	63	Missense	proximal	-1	no	9.982	9.997	EPSD	CCLE	6.449	Up-regulation
CAMK_DAPK_DAPK_DAPK3_ST	P40429	RPL13A	O43293	DAPK3	S77	R82Q	82	Missense	distal	5	no	11.310	11.265	PhosphoSitePlus	CCLE	6.449	Down-regulation
CAMK_DAPK_DAPK_DAPK3_ST	P38936	CDKN1A	O43293	DAPK3	S31	P24T	24	Missense	distal	-7	no	6.680	7.063	EPSD	CCLE	6.449	Up-regulation
CAMK_DAPK_DAPK_DAPK3_ST	Q14457	BECN1	O43293	DAPK3	S90	S93N	93	Missense	distal	3	no	10.465	10.843	PhosphoSitePlus	CCLE	6.449	Up-regulation
CAMK_DAPK_DAPK_DAPK3_ST	Q14457	BECN1	O43293	DAPK3	T91	S93N	93	Missense	proximal	2	no	7.709	7.723	EPSD	CCLE	6.449	Up-regulation
CAMK_DAPK_DAPK_DAPK3_ST	Q14457	BECN1	O43293	DAPK3	T98	S93N	93	Missense	distal	-5	no	7.390	7.075	EPSD	CCLE	6.449	Down-regulation
TK_FGFR_FGFR2_Y	P21802	FGFR2	P21802	FGFR2	Y586	Y586H	586	Missense	central	0	yes	3.301	0.000	EPSD	CCLE	1.189	Loss
TK_FGFR_FGFR2_Y	P21802	FGFR2	P21802	FGFR2	Y588	Y586H	586	Missense	proximal	-2	no	3.238	3.239	EPSD	CCLE	1.189	Up-regulation
TK_FGFR_FGFR2_Y	P21802	FGFR2	P21802	FGFR2	Y656	Y657H	657	Missense	proximal	1	no	3.779	3.777	EPSD	CCLE	1.189	Down-regulation
TK_FGFR_FGFR2_Y	P21802	FGFR2	P21802	FGFR2	Y656	I651S	651	Missense	distal	-5	no	3.779	3.760	EPSD	CCLE	1.189	Down-regulation
TK_FGFR_FGFR2_Y	P21802	FGFR2	P21802	FGFR2	Y657	Y657H	657	Missense	central	0	yes	3.400	0.000	EPSD	CCLE	1.189	Loss
TK_FGFR_FGFR2_Y	P21802	FGFR2	P21802	FGFR2	Y657	I651S	651	Missense	distal	-6	no	3.400	3.071	EPSD	CCLE	1.189	Down-regulation
TK_FGFR_FGFR2_Y	P60484	PTEN	P21802	FGFR2	Y240	F243V	243	Missense	distal	3	no	3.649	3.470	PhosphoSitePlus	CCLE	1.189	Down-regulation
CAMK_CAMKL_BRSK_BRSK1_ST	Q8TDC3	BRSK1	Q8TDC3-2	BRSK1	T500	P501S	501	Missense	proximal	1	no	0.587	0.693	EPSD	CCLE	0.579	Up-regulation
CAMK_CAMKL_BRSK_BRSK1_ST	Q13131	PRKAA1	Q8TDC3-2	BRSK1	S467	Q461R	461	Missense	distal	-6	no	0.697	0.783	EPSD	CCLE	0.579	Up-regulation
CAMK_CAMKL_BRSK_BRSK1_ST	Q13131	PRKAA1	Q8TDC3-2	BRSK1	S496	S494L	494	Missense	proximal	-2	no	0.657	0.617	EPSD	CCLE	0.579	Down-regulation
CAMK_CAMKL_BRSK_BRSK1_ST	Q13131	PRKAA1	Q8TDC3-2	BRSK1	S496	S494W	494	Missense	proximal	-2	no	0.657	0.465	EPSD	CCLE	0.579	Loss
CAMK_CAMKL_BRSK_BRSK1_ST	Q13131	PRKAA1	Q8TDC3-2	BRSK1	S523	L521V	521	Missense	proximal	-2	no	0.695	0.605	EPSD	CCLE	0.579	Down-regulation
CAMK_CAMKL_BRSK_BRSK1_ST	Q13131	PRKAA1	Q8TDC3-2	BRSK1	T526	L521V	521	Missense	distal	-5	no	0.642	0.626	EPSD	CCLE	0.579	Down-regulation
CAMK_CAMKL_BRSK_BRSK1_ST	Q13131	PRKAA1	Q8TDC3-2	BRSK1	S527	L521V	521	Missense	distal	-6	no	0.676	0.656	EPSD	CCLE	0.579	Down-regulation
CAMK_CAMKL_BRSK_BRSK1_ST	P30291	WEE1	Q8TDC3-2	BRSK1	T69	P64S	64	Missense	distal	-5	no	0.595	0.510	EPSD	CCLE	0.579	Loss
CAMK_CAMKL_BRSK_BRSK1_ST	P30291	WEE1	Q8TDC3-2	BRSK1	S571	S573C	573	Missense	proximal	2	no	0.650	0.662	EPSD	CCLE	0.579	Up-regulation
CAMK_CAMKL_BRSK_BRSK1_ST	P30305	CDC25B	Q8TDC3-2	BRSK1	T58	M59I	59	Missense	proximal	1	no	0.721	0.687	EPSD	CCLE	0.579	Down-regulation
CAMK_CAMKL_BRSK_BRSK1_ST	P30305	CDC25B	Q8TDC3-2	BRSK1	S375	R372H	372	Missense	distal	-3	no	1.213	1.210	PhosphoSitePlus	CCLE	0.579	Down-regulation
CAMK_CAMKL_BRSK_BRSK1_ST	P30307	CDC25C	Q8TDC3-2	BRSK1	S451	G456R	456	Missense	distal	5	no	0.689	0.650	EPSD	CCLE	0.579	Down-regulation
TK_Ack_TNK2_Y	Q07912	TNK2	Q07912	TNK2	Y635	Y635C	635	Missense	central	0	yes	0.000	0.000	EPSD	CCLE	0.000	Loss
AGC_Akt_AKT3_ST	Q96ST2	IWS1	Q9Y243	AKT3	S720	G722C	722	Missense	proximal	2	no	3.267	3.423	EPSD;PhosphoSitePlus	CCLE	2.840	Up-regulation
AGC_Akt_AKT3_ST	Q96ST2	IWS1	Q9Y243	AKT3	T721	G722C	722	Missense	proximal	1	no	2.900	2.891	PhosphoSitePlus;EPSD	CCLE	2.840	Down-regulation
AGC_Akt_AKT3_ST	O15119	TBX3	Q9Y243	AKT3	S443	G448C	448	Missense	distal	5	no	2.945	3.170	EPSD	CCLE	2.840	Up-regulation
AGC_Akt_AKT3_ST	O15119	TBX3	Q9Y243	AKT3	S443	S444P	444	Missense	proximal	1	no	2.945	2.975	EPSD	CCLE	2.840	Up-regulation
AGC_Akt_AKT3_ST	O15119	TBX3	Q9Y243	AKT3	T462	P464S	464	Missense	proximal	2	no	3.316	2.990	EPSD	CCLE	2.840	Down-regulation
AGC_Akt_AKT3_ST	O15119	TBX3	Q9Y243	AKT3	S719	E713D	713	Missense	distal	-6	no	6.326	6.312	PhosphoSitePlus	CCLE	2.840	Down-regulation
AGC_Akt_AKT3_ST	O15119	TBX3	Q9Y243	AKT3	S729	D736Y	736	Missense	distal	7	no	3.665	3.606	EPSD	CCLE	2.840	Down-regulation
AGC_Akt_AKT3_ST	O15119	TBX3	Q9Y243	AKT3	S740	R737M	737	Missense	distal	-3	no	3.869	1.359	EPSD	CCLE	2.840	Loss
AGC_Akt_AKT3_ST	O15119	TBX3	Q9Y243	AKT3	S740	D736Y	736	Missense	distal	-4	no	3.869	3.861	EPSD	CCLE	2.840	Down-regulation
AGC_Akt_AKT3_ST	O15119	TBX3	Q9Y243	AKT3	S742	R737M	737	Missense	distal	-5	no	5.611	4.326	EPSD	CCLE	2.840	Down-regulation
AGC_Akt_AKT3_ST	O15119	TBX3	Q9Y243	AKT3	S742	D736Y	736	Missense	distal	-6	no	5.611	5.594	EPSD	CCLE	2.840	Down-regulation
AGC_Akt_AKT3_ST	P15056	BRAF	Q9Y243	AKT3	S429	R435S	435	Missense	distal	6	no	8.364	8.277	EPSD;PhosphoSitePlus	CCLE	2.840	Down-regulation
AGC_Akt_AKT3_ST	P15056	BRAF	Q9Y243	AKT3	S431	R435S	435	Missense	distal	4	no	4.867	5.019	EPSD	CCLE	2.840	Up-regulation
AGC_Akt_AKT3_ST	P15056	BRAF	Q9Y243	AKT3	T440	R435S	435	Missense	distal	-5	no	3.952	2.701	EPSD	CCLE	2.840	Loss
AGC_Akt_AKT3_ST	P15056	BRAF	Q9Y243	AKT3	S446	E451K	451	Missense	distal	5	no	4.270	4.334	EPSD	CCLE	2.840	Up-regulation
AGC_Akt_AKT3_ST	P15056	BRAF	Q9Y243	AKT3	S447	E451K	451	Missense	distal	4	no	5.637	5.677	EPSD	CCLE	2.840	Up-regulation
AGC_Akt_AKT3_ST	P15056	BRAF	Q9Y243	AKT3	S729	A728V	728	Missense	proximal	-1	no	4.901	4.153	EPSD	CCLE	2.840	Down-regulation
STE_STE11_MEKK1_MAP3K1_ST	P46531	NOTCH1	Q13233	MAP3K1	T1997	R1991C	1991	Missense	distal	-6	no	2.767	2.967	EPSD	CCLE	2.285	Up-regulation
STE_STE11_MEKK1_MAP3K1_ST	Q8NHW3	MAFA	Q13233	MAP3K1	T53	P54S	54	Missense	proximal	1	no	2.714	2.371	EPSD	CCLE	2.285	Down-regulation
STE_STE11_MEKK1_MAP3K1_ST	Q8NHW3	MAFA	Q13233	MAP3K1	S65	P66S	66	Missense	proximal	1	no	4.817	4.474	EPSD;PhosphoSitePlus	CCLE	2.285	Down-regulation
STE_STE11_MEKK1_MAP3K1_ST	Q13158	FADD	Q13233	MAP3K1	S194	M193T	193	Missense	proximal	-1	no	3.865	3.868	PhosphoSitePlus	CCLE	2.285	Up-regulation
AGC_RSK_MSK_RPS6KA5_ST	O75582	RPS6KA5	O75582	RPS6KA5	S758	S758G	758	Missense	central	0	yes	2.440	0.000	EPSD;PhosphoSitePlus	CCLE	1.456	Loss
AGC_RSK_MSK_RPS6KA5_ST	O75582	RPS6KA5	O75582	RPS6KA5	S759	S758G	758	Missense	proximal	-1	no	2.201	2.192	EPSD	CCLE	1.456	Down-regulation
AGC_RSK_MSK_RPS6KA5_ST	P54253	ATXN1	O75582	RPS6KA5	S262	A261T	261	Missense	proximal	-1	no	1.676	1.645	EPSD	CCLE	1.456	Down-regulation
AGC_RSK_MSK_RPS6KA5_ST	P54253	ATXN1	O75582	RPS6KA5	S677	D670E	670	Missense	distal	-7	no	1.577	1.574	EPSD	CCLE	1.456	Down-regulation
AGC_RSK_MSK_RPS6KA5_ST	P54253	ATXN1	O75582	RPS6KA5	S775	A768V	768	Missense	distal	-7	no	3.524	3.564	PhosphoSitePlus	CCLE	1.456	Up-regulation
AGC_RSK_MSK_RPS6KA5_ST	P18846	ATF1	O75582	RPS6KA5	S63	R60Q	60	Missense	distal	-3	no	4.068	3.142	PhosphoSitePlus	CCLE	1.456	Down-regulation
AGC_RSK_MSK_RPS6KA5_ST	P18846	ATF1	O75582	RPS6KA5	S63	I67F	67	Missense	distal	4	no	4.068	4.062	PhosphoSitePlus	CCLE	1.456	Down-regulation
AGC_RSK_MSK_RPS6KA5_ST	Q04206	RELA	O75582	RPS6KA5	S338	S340F	340	Missense	proximal	2	no	2.724	2.699	EPSD	CCLE	1.456	Down-regulation
AGC_RSK_MSK_RPS6KA5_ST	Q9H4A3	WNK1	O75582	RPS6KA5	S185	K191N	191	Missense	distal	6	no	2.067	2.070	EPSD	CCLE	1.456	Up-regulation
AGC_RSK_MSK_RPS6KA5_ST	Q9H4A3	WNK1	O75582	RPS6KA5	S1105	R1103Q	1103	Missense	proximal	-2	no	2.890	1.302	EPSD	CCLE	1.456	Loss
AGC_RSK_MSK_RPS6KA5_ST	Q9H4A3	WNK1	O75582	RPS6KA5	S1110	R1103Q	1103	Missense	distal	-7	no	2.208	2.273	EPSD	CCLE	1.456	Up-regulation
AGC_RSK_MSK_RPS6KA5_ST	Q9H4A3	WNK1	O75582	RPS6KA5	S1110	R1117C	1117	Missense	distal	7	no	2.208	2.249	EPSD	CCLE	1.456	Up-regulation
AGC_RSK_MSK_RPS6KA5_ST	Q9H4A3	WNK1	O75582	RPS6KA5	S1285	T1281A	1281	Missense	distal	-4	no	1.504	1.400	EPSD	CCLE	1.456	Loss
AGC_RSK_MSK_RPS6KA5_ST	Q9H4A3	WNK1	O75582	RPS6KA5	S1285	T1286I	1286	Missense	proximal	1	no	1.504	1.502	EPSD	CCLE	1.456	Down-regulation
AGC_RSK_MSK_RPS6KA5_ST	Q9H4A3	WNK1	O75582	RPS6KA5	S1805	L1804V	1804	Missense	proximal	-1	no	1.717	1.704	EPSD	CCLE	1.456	Down-regulation
AGC_RSK_MSK_RPS6KA5_ST	P11831	SRF	O75582	RPS6KA5	S16	S21N	21	Missense	distal	5	no	2.719	2.711	EPSD	CCLE	1.456	Down-regulation
AGC_RSK_MSK_RPS6KA5_ST	P11831	SRF	O75582	RPS6KA5	S79	G73R	73	Missense	distal	-6	no	1.492	1.410	EPSD	CCLE	1.456	Loss
AGC_RSK_MSK_RPS6KA5_ST	P11831	SRF	O75582	RPS6KA5	S237	R235I	235	Missense	proximal	-2	no	2.866	1.056	EPSD	CCLE	1.456	Loss
AGC_RSK_MSK_RPS6KA5_ST	P07101	TH	O75582	RPS6KA5	S71	R68H	68	Missense	distal	-3	no	3.730	2.816	EPSD	CCLE	1.456	Down-regulation
AGC_RSK_MSK_RPS6KA5_ST	P07101	TH	O75582	RPS6KA5	S71	R68C	68	Missense	distal	-3	no	3.730	2.755	EPSD	CCLE	1.456	Down-regulation
TK_EGFR_EGFR_Y	P52735	VAV2	P00533	EGFR	Y224	S226G	226	Missense	proximal	2	no	6.534	6.337	EPSD	CCLE	6.466	Loss
TK_EGFR_EGFR_Y	Q8NFJ5	GPRC5A	P00533	EGFR	Y317	G313E	313	Missense	distal	-4	no	9.261	10.704	EPSD;PhosphoSitePlus	CCLE	6.466	Up-regulation
TK_EGFR_EGFR_Y	Q8NFJ5	GPRC5A	P00533	EGFR	Y317	S321P	321	Missense	distal	4	no	9.261	9.823	EPSD;PhosphoSitePlus	CCLE	6.466	Up-regulation
TK_EGFR_EGFR_Y	Q8NFJ5	GPRC5A	P00533	EGFR	Y320	G313E	313	Missense	distal	-7	no	8.152	8.695	PhosphoSitePlus;EPSD	CCLE	6.466	Up-regulation
TK_EGFR_EGFR_Y	Q8NFJ5	GPRC5A	P00533	EGFR	Y320	S321P	321	Missense	proximal	1	no	8.152	9.007	PhosphoSitePlus;EPSD	CCLE	6.466	Up-regulation
TK_EGFR_EGFR_Y	Q8NFJ5	GPRC5A	P00533	EGFR	Y320	Q325R	325	Missense	distal	5	no	8.152	7.967	PhosphoSitePlus;EPSD	CCLE	6.466	Down-regulation
TK_EGFR_EGFR_Y	P19174	PLCG1	P00533	EGFR	Y496	L495I	495	Missense	proximal	-1	no	6.447	7.053	EPSD	CCLE	6.466	Gain
TK_EGFR_EGFR_Y	P19174	PLCG1	P00533	EGFR	Y496	P500H	500	Missense	distal	4	no	6.447	6.774	EPSD	CCLE	6.466	Gain
TK_EGFR_EGFR_Y	P19174	PLCG1	P00533	EGFR	Y1253	Y1253F	1253	Missense	central	0	yes	11.096	0.000	EPSD	CCLE	6.466	Loss
TK_EGFR_EGFR_Y	Q13480	GAB1	P00533	EGFR	Y406	S402Y	402	Missense	distal	-4	no	12.131	12.000	PhosphoSitePlus;EPSD	CCLE	6.466	Down-regulation
TK_EGFR_EGFR_Y	Q13480	GAB1	P00533	EGFR	Y447	M450T	450	Missense	distal	3	no	12.802	12.960	EPSD;PhosphoSitePlus	CCLE	6.466	Up-regulation
TK_EGFR_EGFR_Y	Q13480	GAB1	P00533	EGFR	Y627	D629E	629	Missense	proximal	2	no	10.746	10.824	EPSD;PhosphoSitePlus	CCLE	6.466	Up-regulation
TK_EGFR_EGFR_Y	O00767	SCD	P00533	EGFR	Y55	D56G	56	Missense	proximal	1	no	15.341	14.936	EPSD;PhosphoSitePlus	CCLE	6.466	Down-regulation
TK_EGFR_EGFR_Y	O00767	SCD	P00533	EGFR	Y59	D56G	56	Missense	distal	-3	no	8.552	5.993	EPSD	CCLE	6.466	Loss
TK_EGFR_EGFR_Y	P18031	PTPN1	P00533	EGFR	Y46	P51S	51	Missense	distal	5	no	7.735	7.962	EPSD	CCLE	6.466	Up-regulation
TK_EGFR_EGFR_Y	P15311	EZR	P00533	EGFR	Y116	P118L	118	Missense	proximal	2	no	10.057	7.192	EPSD	CCLE	6.466	Down-regulation
TK_EGFR_EGFR_Y	P07948	LYN	P00533	EGFR	Y32	N26S	26	Missense	distal	-6	no	9.229	9.166	PhosphoSitePlus	CCLE	6.466	Down-regulation
TK_EGFR_EGFR_Y	P07948	LYN	P00533	EGFR	Y32	E28D	28	Missense	distal	-4	no	9.229	7.464	PhosphoSitePlus	CCLE	6.466	Down-regulation
TK_EGFR_EGFR_Y	P07948	LYN	P00533	EGFR	Y117	N122I	122	Missense	distal	5	no	7.078	6.886	EPSD	CCLE	6.466	Down-regulation
TK_EGFR_EGFR_Y	P07948	LYN	P00533	EGFR	Y397	Y397C	397	Missense	central	0	yes	8.824	0.000	EPSD	CCLE	6.466	Loss
TK_EGFR_EGFR_Y	P07948	LYN	P00533	EGFR	Y397	A403V	403	Missense	distal	6	no	8.824	8.408	EPSD	CCLE	6.466	Down-regulation
TK_EGFR_EGFR_Y	Q8TDY4	ASAP3	P00533	EGFR	Y843	G836R	836	Missense	distal	-7	no	10.611	10.891	EPSD	CCLE	6.466	Up-regulation
TK_EGFR_EGFR_Y	Q3V6T2	CCDC88A	P00533	EGFR	Y1765	R1759Q	1759	Missense	distal	-6	no	9.180	9.187	PhosphoSitePlus;EPSD	CCLE	6.466	Up-regulation
TK_EGFR_EGFR_Y	Q92952	KCNN1	P00533	EGFR	Y109	K102M	102	Missense	distal	-7	no	7.204	7.186	PhosphoSitePlus	CCLE	6.466	Down-regulation
STE_STE20_PAKA_PAK2_ST	Q53QZ3	ARHGAP15	Q13177	PAK2	S292	P295L	295	Missense	distal	3	no	18.434	16.192	EPSD;PhosphoSitePlus	CCLE	14.606	Down-regulation
STE_STE20_PAKA_PAK2_ST	Q53QZ3	ARHGAP15	Q13177	PAK2	S292	K299R	299	Missense	distal	7	no	18.434	23.677	EPSD;PhosphoSitePlus	CCLE	14.606	Up-regulation
STE_STE20_PAKA_PAK2_ST	Q13177	PAK2	Q13177	PAK2	S507	S508N	508	Missense	proximal	1	no	22.830	20.774	EPSD	CCLE	14.606	Down-regulation
STE_STE20_PAKA_PAK2_ST	P05412	JUN	Q13177	PAK2	S48	R54G	54	Missense	distal	6	no	15.111	16.236	EPSD	CCLE	14.606	Up-regulation
STE_STE20_PAKA_PAK2_ST	P05412	JUN	Q13177	PAK2	S58	R54G	54	Missense	distal	-4	no	14.800	16.234	EPSD	CCLE	14.606	Up-regulation
STE_STE20_PAKA_PAK2_ST	P01106	MYC	Q13177	PAK2	S62	P57H	57	Missense	distal	-5	no	23.852	21.223	EPSD	CCLE	14.606	Down-regulation
STE_STE20_PAKA_PAK2_ST	P01106	MYC	Q13177	PAK2	S62	L69I	69	Missense	distal	7	no	23.852	22.289	EPSD	CCLE	14.606	Down-regulation
STE_STE20_PAKA_PAK2_ST	P01106	MYC	Q13177	PAK2	S67	L69I	69	Missense	proximal	2	no	17.246	19.781	EPSD	CCLE	14.606	Up-regulation
STE_STE20_PAKA_PAK2_ST	P01106	MYC	Q13177	PAK2	S67	Y74S	74	Missense	distal	7	no	17.246	13.660	EPSD	CCLE	14.606	Loss
STE_STE20_PAKA_PAK2_ST	P01106	MYC	Q13177	PAK2	S159	Q153R	153	Missense	distal	-6	no	13.916	17.028	EPSD	CCLE	14.606	Gain
STE_STE20_PAKA_PAK2_ST	P01106	MYC	Q13177	PAK2	S250	S252C	252	Missense	proximal	2	no	17.884	13.279	EPSD	CCLE	14.606	Loss
STE_STE20_PAKA_PAK2_ST	P49023	PXN	Q13177	PAK2	S230	V237M	237	Missense	distal	7	no	19.331	12.433	EPSD	CCLE	14.606	Loss
STE_STE20_PAKA_PAK2_ST	P49023	PXN	Q13177	PAK2	S243	E241K	241	Missense	proximal	-2	no	12.903	16.437	EPSD	CCLE	14.606	Gain
STE_STE20_PAKA_PAK2_ST	P49023	PXN	Q13177	PAK2	S243	V237M	237	Missense	distal	-6	no	12.903	17.416	EPSD	CCLE	14.606	Gain
STE_STE20_PAKA_PAK2_ST	P49023	PXN	Q13177	PAK2	S244	E241K	241	Missense	distal	-3	no	4.106	23.120	EPSD	CCLE	14.606	Gain
STE_STE20_PAKA_PAK2_ST	Q05682	CALD1	Q13177	PAK2	S202	K197N	197	Missense	distal	-5	no	39.887	39.014	EPSD	CCLE	14.606	Down-regulation
STE_STE20_PAKA_PAK2_ST	Q05682	CALD1	Q13177	PAK2	S518	A524V	524	Missense	distal	6	no	15.654	15.863	EPSD	CCLE	14.606	Up-regulation
STE_STE20_PAKA_PAK2_ST	Q05682	CALD1	Q13177	PAK2	S714	E707D	707	Missense	distal	-7	no	30.407	31.301	EPSD;PhosphoSitePlus	CCLE	14.606	Up-regulation
STE_STE20_PAKA_PAK2_ST	Q05682	CALD1	Q13177	PAK2	S714	R710H	710	Missense	distal	-4	no	30.407	29.560	EPSD;PhosphoSitePlus	CCLE	14.606	Down-regulation
STE_STE20_PAKA_PAK2_ST	P55210	CASP7	Q13177	PAK2	S29	S34Y	34	Missense	distal	5	no	19.973	18.051	EPSD	CCLE	14.606	Down-regulation
STE_STE20_PAKA_PAK2_ST	P55210	CASP7	Q13177	PAK2	S30	S34Y	34	Missense	distal	4	no	33.997	34.156	PhosphoSitePlus;EPSD	CCLE	14.606	Up-regulation
STE_STE20_PAKA_PAK2_ST	P55210	CASP7	Q13177	PAK2	T173	T173N	173	Missense	central	0	yes	29.180	0.000	EPSD;PhosphoSitePlus	CCLE	14.606	Loss
STE_STE20_PAKA_PAK2_ST	Q16659	MAPK6	Q13177	PAK2	S450	Y453C	453	Missense	distal	3	no	20.229	23.033	EPSD	CCLE	14.606	Up-regulation
STE_STE20_PAKA_PAK2_ST	Q16659	MAPK6	Q13177	PAK2	S451	Y453C	453	Missense	proximal	2	no	25.098	15.300	EPSD	CCLE	14.606	Down-regulation
STE_STE20_PAKA_PAK2_ST	Q16659	MAPK6	Q13177	PAK2	T626	T624S	624	Missense	proximal	-2	no	16.415	0.426	EPSD	CCLE	14.606	Loss
STE_STE20_PAKA_PAK2_ST	P00519	ABL1	Q13177	PAK2	S535	K531N	531	Missense	distal	-4	no	13.734	15.732	EPSD	CCLE	14.606	Gain
STE_STE20_PAKA_PAK2_ST	P00519	ABL1	Q13177	PAK2	T779	G778S	778	Missense	proximal	-1	no	14.837	18.115	EPSD	CCLE	14.606	Up-regulation
STE_STE20_PAKA_PAK2_ST	P00519	ABL1	Q13177	PAK2	T779	P782S	782	Missense	distal	3	no	14.837	9.851	EPSD	CCLE	14.606	Loss
STE_STE20_PAKA_PAK2_ST	P00519	ABL1	Q13177	PAK2	T823	A825V	825	Missense	proximal	2	no	11.468	19.757	EPSD	CCLE	14.606	Gain
STE_STE20_PAKA_PAK2_ST	P00519	ABL1	Q13177	PAK2	S915	P914L	914	Missense	proximal	-1	no	7.582	16.066	EPSD	CCLE	14.606	Gain
STE_STE20_PAKA_PAK2_ST	P00519	ABL1	Q13177	PAK2	S936	T935M	935	Missense	proximal	-1	no	14.636	24.045	EPSD	CCLE	14.606	Up-regulation
STE_STE20_PAKA_PAK2_ST	P00519	ABL1	Q13177	PAK2	S1125	E1123Q	1123	Missense	proximal	-2	no	16.915	16.193	EPSD	CCLE	14.606	Down-regulation
STE_STE20_PAKA_PAK2_ST	P00519	ABL1	Q13177	PAK2	S1125	I1127T	1127	Missense	proximal	2	no	16.915	15.186	EPSD	CCLE	14.606	Down-regulation
STE_STE20_PAKA_PAK2_ST	P00519	ABL1	Q13177	PAK2	S1125	V1128E	1128	Missense	distal	3	no	16.915	15.570	EPSD	CCLE	14.606	Down-regulation
STE_STE20_PAKA_PAK2_ST	Q15796	SMAD2	Q13177	PAK2	T172	L179S	179	Missense	distal	7	no	19.293	13.545	EPSD	CCLE	14.606	Loss
STE_STE20_PAKA_PAK2_ST	Q15796	SMAD2	Q13177	PAK2	S250	L254F	254	Missense	distal	4	no	13.013	15.224	EPSD	CCLE	14.606	Gain
STE_STE20_PAKA_PAK2_ST	Q8IYU2	HACE1	Q13177	PAK2	S385	E387G	387	Missense	proximal	2	no	35.489	38.560	PhosphoSitePlus	CCLE	14.606	Up-regulation
CMGC_MAPK_ERK7_MAPK15_ST	Q8TD08	MAPK15	Q8TD08	MAPK15	T175	V174M	174	Missense	proximal	-1	no	10.983	10.922	EPSD;PhosphoSitePlus	CCLE	5.395	Down-regulation
CMGC_MAPK_ERK7_MAPK15_ST	Q8TD08	MAPK15	Q8TD08	MAPK15	S192	G198R	198	Missense	distal	6	no	10.763	10.354	EPSD;PhosphoSitePlus	CCLE	5.395	Down-regulation
CMGC_MAPK_ERK7_MAPK15_ST	Q8TD08	MAPK15	Q8TD08	MAPK15	S331	R338G	338	Missense	distal	7	no	11.674	12.203	EPSD;PhosphoSitePlus	CCLE	5.395	Up-regulation
TK_Ret_RET_Y	P27986	PIK3R1	P07949	RET	Y203	V197G	197	Missense	distal	-6	no	52.559	52.520	PhosphoSitePlus	CCLE	28.094	Down-regulation
TK_Ret_RET_Y	P07949	RET	P07949	RET	Y687	S688F	688	Missense	proximal	1	no	50.930	47.467	EPSD;PhosphoSitePlus	CCLE	28.094	Down-regulation
TK_Ret_RET_Y	P07949	RET	P07949	RET	Y687	R693H	693	Missense	distal	6	no	50.930	50.696	EPSD;PhosphoSitePlus	CCLE	28.094	Down-regulation
TK_Ret_RET_Y	P07949	RET	P07949	RET	Y900	E902Q	902	Missense	proximal	2	no	36.527	35.779	EPSD;PhosphoSitePlus	CCLE	28.094	Down-regulation
TK_Ret_RET_Y	P07949	RET	P07949	RET	Y905	E902Q	902	Missense	distal	-3	no	53.485	51.545	EPSD;PhosphoSitePlus	CCLE	28.094	Down-regulation
TK_Ret_RET_Y	O15530	PDPK1	P07949	RET	Y156	E153K	153	Missense	distal	-3	no	30.054	30.091	EPSD	CCLE	28.094	Up-regulation
TK_Ret_RET_Y	O15530	PDPK1	P07949	RET	Y373	E370K	370	Missense	distal	-3	no	29.217	29.254	EPSD	CCLE	28.094	Up-regulation
TK_Ret_RET_Y	P19174	PLCG1	P07949	RET	Y506	P500H	500	Missense	distal	-6	no	28.381	28.344	EPSD	CCLE	28.094	Down-regulation
TK_Ret_RET_Y	Q8N4X5	AFAP1L2	P07949	RET	Y124	E125K	125	Missense	proximal	1	no	30.292	30.214	EPSD	CCLE	28.094	Down-regulation
TK_Ret_RET_Y	Q8N4X5	AFAP1L2	P07949	RET	Y457	F455S	455	Missense	proximal	-2	no	38.835	43.974	EPSD	CCLE	28.094	Up-regulation
TK_Ret_RET_Y	Q8N4X5	AFAP1L2	P07949	RET	Y459	F455S	455	Missense	distal	-4	no	21.527	31.483	EPSD	CCLE	28.094	Gain
TK_Ret_RET_Y	Q8N4X5	AFAP1L2	P07949	RET	Y668	R667Q	667	Missense	proximal	-1	no	34.635	34.654	EPSD	CCLE	28.094	Up-regulation
TK_Ret_RET_Y	P45984	MAPK9	P07949	RET	Y185	Y191C	191	Missense	distal	6	no	56.127	56.344	PhosphoSitePlus	CCLE	28.094	Up-regulation
TK_Ret_RET_Y	P45983	MAPK8	P07949	RET	Y185	T188N	188	Missense	distal	3	no	57.788	57.491	PhosphoSitePlus	CCLE	28.094	Down-regulation
TK_Ret_RET_Y	P45983	MAPK8	P07949	RET	Y185	T188I	188	Missense	distal	3	no	57.788	56.552	PhosphoSitePlus	CCLE	28.094	Down-regulation
TK_Ret_RET_Y	Q16539	MAPK14	P07949	RET	Y258	M265L	265	Missense	distal	7	no	32.577	33.578	EPSD	CCLE	28.094	Up-regulation
AGC_Akt_AKT1_ST	P19634	SLC9A1	P31749	AKT1	S703	M696L	696	Missense	distal	-7	no	15.032	15.014	EPSD;PhosphoSitePlus	CCLE	7.780	Down-regulation
AGC_Akt_AKT1_ST	P19634	SLC9A1	P31749	AKT1	S770	T769N	769	Missense	proximal	-1	no	12.104	12.080	EPSD	CCLE	7.780	Down-regulation
AGC_Akt_AKT1_ST	Q06187	BTK	P31749	AKT1	S87	I94M	94	Missense	distal	7	no	8.724	8.762	EPSD	CCLE	7.780	Up-regulation
AGC_Akt_AKT1_ST	Q9NR28	DIABLO	P31749	AKT1	T13	S14L	14	Missense	proximal	1	no	12.671	12.769	EPSD	CCLE	7.780	Up-regulation
AGC_Akt_AKT1_ST	P29474	NOS3	P31749	AKT1	T785	Q788H	788	Missense	distal	3	no	9.168	9.140	EPSD	CCLE	7.780	Down-regulation
AGC_Akt_AKT1_ST	Q86V81	ALYREF	P31749	AKT1	S34	A32V	32	Missense	proximal	-2	no	16.387	15.649	PhosphoSitePlus;EPSD	CCLE	7.780	Down-regulation
AGC_Akt_AKT1_ST	Q86V81	ALYREF	P31749	AKT1	S194	G198C	198	Missense	distal	4	no	10.907	11.079	EPSD	CCLE	7.780	Up-regulation
AGC_Akt_AKT1_ST	P19174	PLCG1	P31749	AKT1	S1248	Y1253F	1253	Missense	distal	5	no	14.465	14.435	PhosphoSitePlus	CCLE	7.780	Down-regulation
AGC_Akt_AKT1_ST	P29375	KDM5A	P31749	AKT1	T223	E226D	226	Missense	distal	3	no	12.552	12.481	EPSD	CCLE	7.780	Down-regulation
AGC_Akt_AKT1_ST	P29375	KDM5A	P31749	AKT1	S225	E226D	226	Missense	proximal	1	no	13.181	13.064	EPSD;PhosphoSitePlus	CCLE	7.780	Down-regulation
AGC_Akt_AKT1_ST	P29375	KDM5A	P31749	AKT1	S399	V405A	405	Missense	distal	6	no	10.261	10.292	EPSD	CCLE	7.780	Up-regulation
AGC_Akt_AKT1_ST	P29375	KDM5A	P31749	AKT1	S811	P812S	812	Missense	proximal	1	no	8.345	8.500	EPSD	CCLE	7.780	Up-regulation
AGC_Akt_AKT1_ST	P29375	KDM5A	P31749	AKT1	S1255	S1255G	1255	Missense	central	0	yes	12.019	0.000	EPSD;PhosphoSitePlus	CCLE	7.780	Loss
AGC_Akt_AKT1_ST	P29375	KDM5A	P31749	AKT1	S1326	S1330F	1330	Missense	distal	4	no	11.803	11.999	EPSD	CCLE	7.780	Up-regulation
AGC_Akt_AKT1_ST	P29375	KDM5A	P31749	AKT1	S1326	V1325A	1325	Missense	proximal	-1	no	11.803	11.817	EPSD	CCLE	7.780	Up-regulation
AGC_Akt_AKT1_ST	P29375	KDM5A	P31749	AKT1	S1410	S1403Y	1403	Missense	distal	-7	no	8.778	8.572	EPSD	CCLE	7.780	Down-regulation
AGC_Akt_AKT1_ST	P49815	TSC2	P31749	AKT1	S540	R537P	537	Missense	distal	-3	no	11.290	4.650	EPSD	CCLE	7.780	Loss
AGC_Akt_AKT1_ST	P49815	TSC2	P31749	AKT1	S540	S538F	538	Missense	proximal	-2	no	11.290	10.423	EPSD	CCLE	7.780	Down-regulation
AGC_Akt_AKT1_ST	P49815	TSC2	P31749	AKT1	T993	L995I	995	Missense	proximal	2	no	12.911	12.800	EPSD	CCLE	7.780	Down-regulation
AGC_Akt_AKT1_ST	P49815	TSC2	P31749	AKT1	S1130	L1137P	1137	Missense	distal	7	no	15.071	15.079	EPSD	CCLE	7.780	Up-regulation
AGC_Akt_AKT1_ST	P49815	TSC2	P31749	AKT1	S1132	L1137P	1137	Missense	distal	5	no	14.362	14.376	EPSD	CCLE	7.780	Up-regulation
AGC_Akt_AKT1_ST	P49815	TSC2	P31749	AKT1	S1364	I1357L	1357	Missense	distal	-7	no	9.317	9.456	EPSD	CCLE	7.780	Up-regulation
AGC_Akt_AKT1_ST	P49815	TSC2	P31749	AKT1	S1364	V1363I	1363	Missense	proximal	-1	no	9.317	9.303	EPSD	CCLE	7.780	Down-regulation
AGC_Akt_AKT1_ST	P49815	TSC2	P31749	AKT1	S1364	E1366K	1366	Missense	proximal	2	no	9.317	9.522	EPSD	CCLE	7.780	Up-regulation
AGC_Akt_AKT1_ST	P49815	TSC2	P31749	AKT1	S1418	A1416V	1416	Missense	proximal	-2	no	8.245	7.507	EPSD	CCLE	7.780	Loss
AGC_Akt_AKT1_ST	P49815	TSC2	P31749	AKT1	S1420	A1416V	1416	Missense	distal	-4	no	13.504	13.132	EPSD	CCLE	7.780	Down-regulation
AGC_Akt_AKT1_ST	P49815	TSC2	P31749	AKT1	T1422	A1416V	1416	Missense	distal	-6	no	7.861	7.841	EPSD	CCLE	7.780	Down-regulation
AGC_Akt_AKT1_ST	P49815	TSC2	P31749	AKT1	S1454	P1458T	1458	Missense	distal	4	no	10.888	10.727	EPSD	CCLE	7.780	Down-regulation
AGC_Akt_AKT1_ST	P49815	TSC2	P31749	AKT1	T1462	P1458T	1458	Missense	distal	-4	no	14.274	15.067	PhosphoSitePlus;EPSD	CCLE	7.780	Up-regulation
AGC_Akt_AKT1_ST	P49815	TSC2	P31749	AKT1	S1464	P1458T	1458	Missense	distal	-6	no	8.023	8.118	EPSD	CCLE	7.780	Up-regulation
AGC_Akt_AKT1_ST	P49815	TSC2	P31749	AKT1	S1799	F1806L	1806	Missense	distal	7	no	8.617	8.624	EPSD	CCLE	7.780	Up-regulation
AGC_Akt_AKT1_ST	P14618	PKM	P31749	AKT1	S519	G514R	514	Missense	distal	-5	no	12.016	16.081	EPSD	CCLE	7.780	Up-regulation
AGC_Akt_AKT1_ST	P02545	LMNA	P31749	AKT1	T224	T224A	224	Missense	central	0	yes	12.014	0.000	EPSD	CCLE	7.780	Loss
AGC_Akt_AKT1_ST	P02545	LMNA	P31749	AKT1	S423	R427C	427	Missense	distal	4	no	9.391	9.725	EPSD	CCLE	7.780	Up-regulation
AGC_Akt_AKT1_ST	P02545	LMNA	P31749	AKT1	T424	R427C	427	Missense	distal	3	no	8.524	8.363	EPSD	CCLE	7.780	Down-regulation
AGC_Akt_AKT1_ST	P02545	LMNA	P31749	AKT1	S652	P658S	658	Missense	distal	6	no	8.128	8.222	EPSD	CCLE	7.780	Up-regulation
AGC_Akt_AKT1_ST	P02545	LMNA	P31749	AKT1	S657	P658S	658	Missense	proximal	1	no	12.872	13.027	EPSD	CCLE	7.780	Up-regulation
AGC_Akt_AKT1_ST	P38398	BRCA1	P31749	AKT1	T336	N343K	343	Missense	distal	7	no	7.874	7.909	EPSD	CCLE	7.780	Up-regulation
AGC_Akt_AKT1_ST	P38398	BRCA1	P31749	AKT1	S844	E851G	851	Missense	distal	7	no	12.608	12.568	EPSD	CCLE	7.780	Down-regulation
AGC_Akt_AKT1_ST	P38398	BRCA1	P31749	AKT1	S1328	M1324V	1324	Missense	distal	-4	no	12.039	11.855	EPSD	CCLE	7.780	Down-regulation
AGC_Akt_AKT1_ST	P38398	BRCA1	P31749	AKT1	S1330	M1324V	1324	Missense	distal	-6	no	8.174	8.160	EPSD	CCLE	7.780	Down-regulation
AGC_Akt_AKT1_ST	P55211	CASP9	P31749	AKT1	T125	R122K	122	Missense	distal	-3	no	10.550	6.029	EPSD	CCLE	7.780	Loss
AGC_Akt_AKT1_ST	O60343	TBC1D4	P31749	AKT1	S318	V322M	322	Missense	distal	4	no	15.833	15.816	PhosphoSitePlus;EPSD	CCLE	7.780	Down-regulation
AGC_Akt_AKT1_ST	O60343	TBC1D4	P31749	AKT1	S341	P343S	343	Missense	proximal	2	no	16.535	16.872	EPSD;PhosphoSitePlus	CCLE	7.780	Up-regulation
AGC_Akt_AKT1_ST	O60343	TBC1D4	P31749	AKT1	S597	S597R	597	Missense	central	0	yes	12.000	0.000	EPSD	CCLE	7.780	Loss
AGC_Akt_AKT1_ST	O60343	TBC1D4	P31749	AKT1	S600	S597R	597	Missense	distal	-3	no	2.633	10.409	EPSD	CCLE	7.780	Gain
AGC_Akt_AKT1_ST	O60343	TBC1D4	P31749	AKT1	T642	R639W	639	Missense	distal	-3	no	16.897	7.957	EPSD;PhosphoSitePlus	CCLE	7.780	Down-regulation
AGC_Akt_AKT1_ST	O60343	TBC1D4	P31749	AKT1	S644	R639W	639	Missense	distal	-5	no	11.295	5.775	EPSD	CCLE	7.780	Loss
AGC_Akt_AKT1_ST	O60343	TBC1D4	P31749	AKT1	T749	S750L	750	Missense	proximal	1	no	12.927	13.025	EPSD	CCLE	7.780	Up-regulation
AGC_Akt_AKT1_ST	O60343	TBC1D4	P31749	AKT1	S751	S750L	750	Missense	proximal	-1	no	16.107	16.079	EPSD;PhosphoSitePlus	CCLE	7.780	Down-regulation
AGC_Akt_AKT1_ST	O60343	TBC1D4	P31749	AKT1	S771	S771F	771	Missense	central	0	yes	11.807	0.000	EPSD	CCLE	7.780	Loss
AGC_Akt_AKT1_ST	Q2PPJ7	RALGAPA2	P31749	AKT1	S362	H361D	361	Missense	proximal	-1	no	8.057	8.043	EPSD	CCLE	7.780	Down-regulation
AGC_Akt_AKT1_ST	Q2PPJ7	RALGAPA2	P31749	AKT1	S364	H361D	361	Missense	distal	-3	no	9.946	8.694	EPSD	CCLE	7.780	Down-regulation
AGC_Akt_AKT1_ST	Q2PPJ7	RALGAPA2	P31749	AKT1	S980	S975R	975	Missense	distal	-5	no	4.500	8.970	EPSD	CCLE	7.780	Gain
AGC_Akt_AKT1_ST	Q2PPJ7	RALGAPA2	P31749	AKT1	T1646	I1649F	1649	Missense	distal	3	no	8.788	8.820	EPSD	CCLE	7.780	Up-regulation
AGC_Akt_AKT1_ST	Q2PPJ7	RALGAPA2	P31749	AKT1	T1646	D1639A	1639	Missense	distal	-7	no	8.788	9.010	EPSD	CCLE	7.780	Up-regulation
AGC_Akt_AKT1_ST	Q3V6T2	CCDC88A	P31749	AKT1	S1151	D1154E	1154	Missense	distal	3	no	8.348	8.419	EPSD	CCLE	7.780	Up-regulation
AGC_Akt_AKT1_ST	Q3V6T2	CCDC88A	P31749	AKT1	S1417	P1422R	1422	Missense	distal	5	no	15.901	15.961	PhosphoSitePlus	CCLE	7.780	Up-regulation
AGC_Akt_AKT1_ST	Q3V6T2	CCDC88A	P31749	AKT1	S1417	S1417Y	1417	Missense	central	0	yes	15.901	0.000	PhosphoSitePlus	CCLE	7.780	Loss
AGC_Akt_AKT1_ST	Q3V6T2	CCDC88A	P31749	AKT1	T1419	P1422R	1422	Missense	distal	3	no	12.092	12.156	EPSD	CCLE	7.780	Up-regulation
AGC_Akt_AKT1_ST	Q3V6T2	CCDC88A	P31749	AKT1	T1419	S1417Y	1417	Missense	proximal	-2	no	12.092	11.170	EPSD	CCLE	7.780	Down-regulation
AGC_Akt_AKT1_ST	Q3V6T2	CCDC88A	P31749	AKT1	S1425	P1422R	1422	Missense	distal	-3	no	6.503	13.143	EPSD	CCLE	7.780	Gain
AGC_Akt_AKT1_ST	Q3V6T2	CCDC88A	P31749	AKT1	S1427	P1422R	1422	Missense	distal	-5	no	12.029	16.039	EPSD	CCLE	7.780	Up-regulation
AGC_Akt_AKT1_ST	Q3V6T2	CCDC88A	P31749	AKT1	S1491	R1488C	1488	Missense	distal	-3	no	10.933	4.759	EPSD	CCLE	7.780	Loss
AGC_Akt_AKT1_ST	Q3V6T2	CCDC88A	P31749	AKT1	T1764	R1759Q	1759	Missense	distal	-5	no	8.207	3.980	EPSD	CCLE	7.780	Loss
AGC_Akt_AKT1_ST	P42345	MTOR	P31749	AKT1	T248	K243R	243	Missense	distal	-5	no	5.758	8.155	EPSD	CCLE	7.780	Gain
AGC_Akt_AKT1_ST	P42345	MTOR	P31749	AKT1	S1821	G1822V	1822	Missense	proximal	1	no	11.710	12.014	EPSD	CCLE	7.780	Up-regulation
AGC_Akt_AKT1_ST	P42345	MTOR	P31749	AKT1	S2221	R2217W	2217	Missense	distal	-4	no	8.739	7.189	EPSD	CCLE	7.780	Loss
AGC_Akt_AKT1_ST	Q13045	FLII	P31749	AKT1	T818	H812P	812	Missense	distal	-6	no	14.407	14.428	EPSD	CCLE	7.780	Up-regulation
AGC_Akt_AKT1_ST	Q9UGI0	ZRANB1	P31749	AKT1	T694	C693Y	693	Missense	proximal	-1	no	11.373	11.408	EPSD	CCLE	7.780	Up-regulation
AGC_Akt_AKT1_ST	Q13043	STK4	P31749	AKT1	T120	K119R	119	Missense	proximal	-1	no	13.999	14.003	EPSD;PhosphoSitePlus	CCLE	7.780	Up-regulation
AGC_Akt_AKT1_ST	Q13043	STK4	P31749	AKT1	T122	K119R	119	Missense	distal	-3	no	11.495	16.015	EPSD	CCLE	7.780	Up-regulation
AGC_Akt_AKT1_ST	Q99683	MAP3K5	P31749	AKT1	S83	R78Q	78	Missense	distal	-5	no	15.754	11.527	PhosphoSitePlus	CCLE	7.780	Down-regulation
AGC_Akt_AKT1_ST	Q99683	MAP3K5	P31749	AKT1	S615	C621R	621	Missense	distal	6	no	9.337	9.539	EPSD	CCLE	7.780	Up-regulation
AGC_Akt_AKT1_ST	O43464	HTRA2	P31749	AKT1	S13	G9V	9	Missense	distal	-4	no	10.311	9.946	EPSD	CCLE	7.780	Down-regulation
AGC_Akt_AKT1_ST	Q9UN36	NDRG2	P31749	AKT1	T330	A336S	336	Missense	distal	6	no	10.623	10.705	EPSD	CCLE	7.780	Up-regulation
AGC_Akt_AKT1_ST	Q9UN36	NDRG2	P31749	AKT1	S332	A336S	336	Missense	distal	4	no	15.948	15.823	EPSD;PhosphoSitePlus	CCLE	7.780	Down-regulation
AGC_Akt_AKT1_ST	Q9UN36	NDRG2	P31749	AKT1	T334	A336S	336	Missense	proximal	2	no	9.795	10.171	EPSD	CCLE	7.780	Up-regulation
AGC_Akt_AKT1_ST	Q9UN36	NDRG2	P31749	AKT1	S346	R347C	347	Missense	proximal	1	no	13.688	13.159	EPSD	CCLE	7.780	Down-regulation
AGC_Akt_AKT1_ST	Q9UN36	NDRG2	P31749	AKT1	T348	R347C	347	Missense	proximal	-1	no	15.892	15.822	PhosphoSitePlus;EPSD	CCLE	7.780	Down-regulation
AGC_Akt_AKT1_ST	Q9UN36	NDRG2	P31749	AKT1	S350	R347C	347	Missense	distal	-3	no	19.104	12.931	EPSD	CCLE	7.780	Down-regulation
AGC_Akt_AKT1_ST	Q9UN36	NDRG2	P31749	AKT1	S352	R347C	347	Missense	distal	-5	no	11.781	7.705	EPSD	CCLE	7.780	Loss
AGC_Akt_AKT1_ST	O95999	BCL10	P31749	AKT1	T52	I55S	55	Missense	distal	3	no	11.782	11.913	EPSD	CCLE	7.780	Up-regulation
AGC_Akt_AKT1_ST	P35240	NF2	P31749	AKT1	S13	F11L	11	Missense	proximal	-2	no	9.220	9.230	EPSD	CCLE	7.780	Up-regulation
AGC_Akt_AKT1_ST	P35240	NF2	P31749	AKT1	T230	A223T	223	Missense	distal	-7	no	10.354	10.553	EPSD;PhosphoSitePlus	CCLE	7.780	Up-regulation
AGC_Akt_AKT1_ST	P35240	NF2	P31749	AKT1	T230	G235A	235	Missense	distal	5	no	10.354	10.366	EPSD;PhosphoSitePlus	CCLE	7.780	Up-regulation
AGC_Akt_AKT1_ST	Q92547	TOPBP1	P31749	AKT1	T779	V778A	778	Missense	proximal	-1	no	8.056	8.071	EPSD	CCLE	7.780	Up-regulation
AGC_Akt_AKT1_ST	Q92547	TOPBP1	P31749	AKT1	S921	A927T	927	Missense	distal	6	no	8.988	9.090	EPSD	CCLE	7.780	Up-regulation
AGC_Akt_AKT1_ST	Q92547	TOPBP1	P31749	AKT1	T1256	E1252Q	1252	Missense	distal	-4	no	10.715	10.691	EPSD	CCLE	7.780	Down-regulation
AGC_Akt_AKT1_ST	Q15672	TWIST1	P31749	AKT1	S42	G36V	36	Missense	distal	-6	no	18.341	18.345	EPSD;PhosphoSitePlus	CCLE	7.780	Up-regulation
AGC_Akt_AKT1_ST	Q15672	TWIST1	P31749	AKT1	T121	S123P	123	Missense	proximal	2	no	14.091	13.755	PhosphoSitePlus;EPSD	CCLE	7.780	Down-regulation
AGC_Akt_AKT1_ST	Q15672	TWIST1	P31749	AKT1	S123	S123P	123	Missense	central	0	yes	16.369	0.000	EPSD;PhosphoSitePlus	CCLE	7.780	Loss
AGC_Akt_AKT1_ST	Q8TDN4	CABLES1	P31749	AKT1	S429	R431C	431	Missense	proximal	2	no	11.263	10.610	EPSD	CCLE	7.780	Down-regulation
AGC_Akt_AKT1_ST	Q8TDN4	CABLES1	P31749	AKT1	S434	R431C	431	Missense	distal	-3	no	12.832	6.659	EPSD	CCLE	7.780	Loss
AGC_Akt_AKT1_ST	O75030	MITF	P31749	AKT1	S512	S512N	512	Missense	central	0	yes	11.955	0.000	EPSD	CCLE	7.780	Loss
AGC_Akt_AKT1_ST	O75030	MITF	P31749	AKT1	S515	S512N	512	Missense	distal	-3	no	8.872	9.172	EPSD	CCLE	7.780	Up-regulation
AGC_Akt_AKT1_ST	O75030	MITF	P31749	AKT1	S516	S512N	512	Missense	distal	-4	no	15.700	15.133	PhosphoSitePlus	CCLE	7.780	Down-regulation
AGC_Akt_AKT1_ST	O75030	MITF	P31749	AKT1	S518	S512N	512	Missense	distal	-6	no	11.452	11.405	EPSD	CCLE	7.780	Down-regulation
AGC_Akt_AKT1_ST	P51617	IRAK1	P31749	AKT1	T66	T66M	66	Missense	central	0	yes	8.706	0.000	EPSD	CCLE	7.780	Loss
AGC_Akt_AKT1_ST	P51617	IRAK1	P31749	AKT1	S556	A558V	558	Missense	proximal	2	no	11.753	11.591	EPSD	CCLE	7.780	Down-regulation
AGC_Akt_AKT1_ST	P62136	PPP1CA	P31749	AKT1	S48	Q49E	49	Missense	proximal	1	no	8.633	8.687	EPSD	CCLE	7.780	Up-regulation
AGC_Akt_AKT1_ST	P62136	PPP1CA	P31749	AKT1	S48	K41N	41	Missense	distal	-7	no	8.633	8.476	EPSD	CCLE	7.780	Down-regulation
AGC_Akt_AKT1_ST	O75376	NCOR1	P31749	AKT1	S875	A868T	868	Missense	distal	-7	no	8.222	8.421	EPSD	CCLE	7.780	Up-regulation
AGC_Akt_AKT1_ST	O75376	NCOR1	P31749	AKT1	T1232	I1225T	1225	Missense	distal	-7	no	10.472	10.895	EPSD	CCLE	7.780	Up-regulation
AGC_Akt_AKT1_ST	O75376	NCOR1	P31749	AKT1	T1361	R1356G	1356	Missense	distal	-5	no	8.177	4.113	EPSD	CCLE	7.780	Loss
AGC_Akt_AKT1_ST	O75376	NCOR1	P31749	AKT1	S1592	F1587L	1587	Missense	distal	-5	no	11.967	11.362	EPSD	CCLE	7.780	Down-regulation
AGC_Akt_AKT1_ST	O75376	NCOR1	P31749	AKT1	S1955	S1962C	1962	Missense	distal	7	no	8.599	8.476	EPSD	CCLE	7.780	Down-regulation
AGC_Akt_AKT1_ST	O75376	NCOR1	P31749	AKT1	T1968	S1962C	1962	Missense	distal	-6	no	9.539	9.393	EPSD	CCLE	7.780	Down-regulation
AGC_Akt_AKT1_ST	O75376	NCOR1	P31749	AKT1	S2070	S2069P	2069	Missense	proximal	-1	no	8.269	8.240	EPSD	CCLE	7.780	Down-regulation
AGC_Akt_AKT1_ST	O75376	NCOR1	P31749	AKT1	S2219	D2223N	2223	Missense	distal	4	no	8.285	8.169	EPSD	CCLE	7.780	Down-regulation
AGC_Akt_AKT1_ST	O75376	NCOR1	P31749	AKT1	S2394	P2398L	2398	Missense	distal	4	no	11.708	11.741	EPSD	CCLE	7.780	Up-regulation
AGC_Akt_AKT1_ST	O75376	NCOR1	P31749	AKT1	S2394	M2390L	2390	Missense	distal	-4	no	11.708	11.494	EPSD	CCLE	7.780	Down-regulation
AGC_Akt_AKT1_ST	O75376	NCOR1	P31749	AKT1	T2396	P2398L	2398	Missense	proximal	2	no	9.216	9.006	EPSD	CCLE	7.780	Down-regulation
AGC_Akt_AKT1_ST	O75376	NCOR1	P31749	AKT1	T2396	M2390L	2390	Missense	distal	-6	no	9.216	9.227	EPSD	CCLE	7.780	Up-regulation
AGC_Akt_AKT1_ST	P12755	SKI	P31749	AKT1	S325	I332T	332	Missense	distal	7	no	8.452	8.559	EPSD	CCLE	7.780	Up-regulation
AGC_Akt_AKT1_ST	P12755	SKI	P31749	AKT1	S326	I332T	332	Missense	distal	6	no	10.792	10.977	EPSD	CCLE	7.780	Up-regulation
AGC_Akt_AKT1_ST	P12755	SKI	P31749	AKT1	S720	G722D	722	Missense	proximal	2	no	8.380	8.114	EPSD	CCLE	7.780	Down-regulation
AGC_Akt_AKT1_ST	P12755	SKI	P31749	AKT1	S720	E725A	725	Missense	distal	5	no	8.380	8.362	EPSD	CCLE	7.780	Down-regulation
AGC_Akt_AKT1_ST	P05106	ITGB3	P31749	AKT1	T441	P444L	444	Missense	distal	3	no	9.003	8.986	EPSD	CCLE	7.780	Down-regulation
AGC_Akt_AKT1_ST	P05106	ITGB3	P31749	AKT1	T777	I783T	783	Missense	distal	6	no	9.005	9.190	EPSD	CCLE	7.780	Up-regulation
AGC_Akt_AKT1_ST	P05106	ITGB3	P31749	AKT1	S778	I783T	783	Missense	distal	5	no	9.215	9.312	EPSD	CCLE	7.780	Up-regulation
AGC_Akt_AKT1_ST	P05106	ITGB3	P31749	AKT1	T779	I783T	783	Missense	distal	4	no	8.504	8.237	PhosphoSitePlus	CCLE	7.780	Down-regulation
AGC_Akt_AKT1_ST	P05106	ITGB3	P31749	AKT1	T779	R786W	786	Missense	distal	7	no	8.504	8.405	PhosphoSitePlus	CCLE	7.780	Down-regulation
AGC_Akt_AKT1_ST	Q9BXL7	CARD11	P31749	AKT1	S562	E566G	566	Missense	distal	4	no	7.778	7.874	EPSD	CCLE	7.780	Gain
AGC_Akt_AKT1_ST	Q9BXL7	CARD11	P31749	AKT1	S562	S558T	558	Missense	distal	-4	no	7.778	7.834	EPSD	CCLE	7.780	Gain
AGC_Akt_AKT1_ST	P98177	FOXO4	P31749	AKT1	S197	R194Q	194	Missense	distal	-3	no	15.494	8.283	EPSD;PhosphoSitePlus	CCLE	7.780	Down-regulation
AGC_Akt_AKT1_ST	P98177	FOXO4	P31749	AKT1	S217	P216T	216	Missense	proximal	-1	no	9.924	9.959	EPSD	CCLE	7.780	Up-regulation
AGC_Akt_AKT1_ST	P98177	FOXO4	P31749	AKT1	S260	P258Q	258	Missense	proximal	-2	no	11.154	11.277	EPSD	CCLE	7.780	Up-regulation
AGC_Akt_AKT1_ST	P98177	FOXO4	P31749	AKT1	S262	P258Q	258	Missense	distal	-4	no	16.238	16.438	PhosphoSitePlus;EPSD	CCLE	7.780	Up-regulation
AGC_Akt_AKT1_ST	P10276	RARA	P31749	AKT1	S447	P440L	440	Missense	distal	-7	no	9.176	9.137	EPSD	CCLE	7.780	Down-regulation
AGC_Akt_AKT1_ST	Q96S44	TP53RK	P31749	AKT1	S34	L36M	36	Missense	proximal	2	no	11.604	11.733	EPSD	CCLE	7.780	Up-regulation
AGC_Akt_AKT1_ST	Q96S44	TP53RK	P31749	AKT1	S34	R31L	31	Missense	distal	-3	no	11.604	4.610	EPSD	CCLE	7.780	Loss
AGC_Akt_AKT1_ST	P08727	KRT19	P31749	AKT1	S35	R32H	32	Missense	distal	-3	no	10.975	6.276	PhosphoSitePlus	CCLE	7.780	Loss
AGC_Akt_AKT1_ST	P08727	KRT19	P31749	AKT1	S93	L91M	91	Missense	proximal	-2	no	9.315	9.332	EPSD	CCLE	7.780	Up-regulation
AGC_Akt_AKT1_ST	P98170	XIAP	P31749	AKT1	T32	A34G	34	Missense	proximal	2	no	10.213	10.257	EPSD	CCLE	7.780	Up-regulation
AGC_Akt_AKT1_ST	Q92879	CELF1	P31749	AKT1	S52	S58C	58	Missense	distal	6	no	8.547	8.344	EPSD	CCLE	7.780	Down-regulation
AGC_Akt_AKT1_ST	Q92879	CELF1	P31749	AKT1	S52	V47I	47	Missense	distal	-5	no	8.547	8.294	EPSD	CCLE	7.780	Down-regulation
AGC_Akt_AKT1_ST	P08047	SP1	P31749	AKT1	S42	G44S	44	Missense	proximal	2	no	11.770	12.102	EPSD;PhosphoSitePlus	CCLE	7.780	Up-regulation
AGC_Akt_AKT1_ST	P08047	SP1	P31749	AKT1	S698	R694C	694	Missense	distal	-4	no	7.812	6.133	PhosphoSitePlus;EPSD	CCLE	7.780	Loss
AGC_Akt_AKT1_ST	P49841	GSK3B	P31749	AKT1	S147	T152M	152	Missense	distal	5	no	10.133	10.076	EPSD	CCLE	7.780	Down-regulation
AGC_Akt_AKT1_ST	P61247	RPS3A	P31749	AKT1	T10	L9F	9	Missense	proximal	-1	no	10.266	10.260	EPSD;PhosphoSitePlus	CCLE	7.780	Down-regulation
AGC_Akt_AKT1_ST	Q9H6Z4	RANBP3	P31749	AKT1	S221	V227L	227	Missense	distal	6	no	11.061	11.071	EPSD	CCLE	7.780	Up-regulation
AGC_Akt_AKT1_ST	Q9BVI0	PHF20	P31749	AKT1	S265	A267T	267	Missense	proximal	2	no	15.666	15.967	PhosphoSitePlus;EPSD	CCLE	7.780	Up-regulation
AGC_Akt_AKT1_ST	Q15910	EZH2	P31749	AKT1	S8	C14Y	14	Missense	distal	6	no	8.046	8.160	EPSD	CCLE	7.780	Up-regulation
AGC_Akt_AKT1_ST	Q15910	EZH2	P31749	AKT1	S21	C14Y	14	Missense	distal	-7	no	15.763	15.980	PhosphoSitePlus	CCLE	7.780	Up-regulation
AGC_Akt_AKT1_ST	Q15910	EZH2	P31749	AKT1	S690	Y696C	696	Missense	distal	6	no	8.977	8.863	EPSD	CCLE	7.780	Down-regulation
AGC_Akt_AKT1_ST	Q96BF3	TMIGD2	P31749	AKT1	T268	G275V	275	Missense	distal	7	no	8.266	8.284	EPSD	CCLE	7.780	Up-regulation
AGC_Akt_AKT1_ST	P49760	CLK2	P31749	AKT1	S9	S14N	14	Missense	distal	5	no	13.250	13.215	EPSD	CCLE	7.780	Down-regulation
AGC_Akt_AKT1_ST	P49760	CLK2	P31749	AKT1	S9	P2S	2	Missense	distal	-7	no	13.250	13.444	EPSD	CCLE	7.780	Up-regulation
AGC_Akt_AKT1_ST	P49760	CLK2	P31749	AKT1	S10	S14N	14	Missense	distal	4	no	9.218	9.328	EPSD	CCLE	7.780	Up-regulation
AGC_Akt_AKT1_ST	P49760	CLK2	P31749	AKT1	S17	S14N	14	Missense	distal	-3	no	8.588	8.888	EPSD	CCLE	7.780	Up-regulation
AGC_Akt_AKT1_ST	P49760	CLK2	P31749	AKT1	S36	T42I	42	Missense	distal	6	no	17.235	17.050	EPSD	CCLE	7.780	Down-regulation
AGC_Akt_AKT1_ST	P49760	CLK2	P31749	AKT1	S142	E148D	148	Missense	distal	6	no	11.120	11.030	EPSD	CCLE	7.780	Down-regulation
AGC_Akt_AKT1_ST	P10275	AR	P31749	AKT1	S121	Q118H	118	Missense	distal	-3	no	5.353	7.866	EPSD	CCLE	7.780	Gain
AGC_Akt_AKT1_ST	Q96B36	AKT1S1	P31749	AKT1	T233	D232E	232	Missense	proximal	-1	no	9.167	9.200	EPSD	CCLE	7.780	Up-regulation
AGC_Akt_AKT1_ST	Q13950	RUNX2	P31749	AKT1	S28	S32R	32	Missense	distal	4	no	13.000	13.011	EPSD;PhosphoSitePlus	CCLE	7.780	Up-regulation
AGC_Akt_AKT1_ST	Q13950	RUNX2	P31749	AKT1	S31	S32R	32	Missense	proximal	1	no	8.646	8.791	EPSD	CCLE	7.780	Up-regulation
AGC_Akt_AKT1_ST	Q13950	RUNX2	P31749	AKT1	S118	C123Y	123	Missense	distal	5	no	11.719	11.795	EPSD	CCLE	7.780	Up-regulation
AGC_Akt_AKT1_ST	Q13950	RUNX2	P31749	AKT1	S196	T200I	200	Missense	distal	4	no	11.166	11.432	EPSD;PhosphoSitePlus	CCLE	7.780	Up-regulation
AGC_Akt_AKT1_ST	Q13950	RUNX2	P31749	AKT1	T198	T200I	200	Missense	proximal	2	no	10.635	10.053	EPSD;PhosphoSitePlus	CCLE	7.780	Down-regulation
AGC_Akt_AKT1_ST	Q13950	RUNX2	P31749	AKT1	S294	A291T	291	Missense	distal	-3	no	8.071	7.353	EPSD	CCLE	7.780	Loss
AGC_Akt_AKT1_ST	Q13950	RUNX2	P31749	AKT1	S294	Q301K	301	Missense	distal	7	no	8.071	8.119	EPSD	CCLE	7.780	Up-regulation
AGC_Akt_AKT1_ST	O60825	PFKFB2	P31749	AKT1	S29	A31T	31	Missense	proximal	2	no	8.511	8.812	EPSD	CCLE	7.780	Up-regulation
AGC_Akt_AKT1_ST	Q96ST2	IWS1	P31749	AKT1	S720	G722C	722	Missense	proximal	2	no	16.574	16.081	EPSD;PhosphoSitePlus	CCLE	7.780	Down-regulation
AGC_Akt_AKT1_ST	O60285	NUAK1	P31749	AKT1	S413	E418K	418	Missense	distal	5	no	11.837	11.871	EPSD	CCLE	7.780	Up-regulation
AGC_Akt_AKT1_ST	Q5XUX0	FBXO31	P31749	AKT1	T127	C131R	131	Missense	distal	4	no	8.142	7.808	EPSD	CCLE	7.780	Down-regulation
AGC_Akt_AKT1_ST	Q9Y283	INVS	P31749	AKT1	S1023	R1027H	1027	Missense	distal	4	no	9.831	10.016	EPSD	CCLE	7.780	Up-regulation
AGC_Akt_AKT1_ST	Q9Y283	INVS	P31749	AKT1	S1030	R1027H	1027	Missense	distal	-3	no	9.814	5.116	EPSD	CCLE	7.780	Loss
AGC_Akt_AKT1_ST	Q9Y283	INVS	P31749	AKT1	S1032	R1027H	1027	Missense	distal	-5	no	8.309	5.214	EPSD	CCLE	7.780	Loss
AGC_Akt_AKT1_ST	Q9Y283	INVS	P31749	AKT1	S1050	S1043G	1043	Missense	distal	-7	no	14.182	13.996	EPSD	CCLE	7.780	Down-regulation
AGC_Akt_AKT1_ST	Q9UPY5	SLC7A11	P31749	AKT1	S51	I58T	58	Missense	distal	7	no	9.889	9.997	EPSD	CCLE	7.780	Up-regulation
AGC_Akt_AKT1_ST	Q9UPY5	SLC7A11	P31749	AKT1	S51	T45A	45	Missense	distal	-6	no	9.889	9.803	EPSD	CCLE	7.780	Down-regulation
AGC_Akt_AKT1_ST	O43524	FOXO3	P31749	AKT1	S30	R27G	27	Missense	distal	-3	no	10.570	3.814	EPSD	CCLE	7.780	Loss
AGC_Akt_AKT1_ST	O43524	FOXO3	P31749	AKT1	T32	R27G	27	Missense	distal	-5	no	15.456	11.391	PhosphoSitePlus;EPSD	CCLE	7.780	Down-regulation
AGC_Akt_AKT1_ST	O43524	FOXO3	P31749	AKT1	S666	P672S	672	Missense	distal	6	no	8.863	8.956	EPSD	CCLE	7.780	Up-regulation
AGC_Akt_AKT1_ST	P46527	CDKN1B	P31749	AKT1	S10	S12I	12	Missense	proximal	2	no	9.798	9.142	EPSD;PhosphoSitePlus	CCLE	7.780	Down-regulation
AGC_Akt_AKT1_ST	P84103	SRSF3	P31749	AKT1	S108	R107S	107	Missense	proximal	-1	no	10.457	10.446	EPSD	CCLE	7.780	Down-regulation
AGC_Akt_AKT1_ST	P84103	SRSF3	P31749	AKT1	S108	S115F	115	Missense	distal	7	no	10.457	10.383	EPSD	CCLE	7.780	Down-regulation
AGC_Akt_AKT1_ST	P84103	SRSF3	P31749	AKT1	S115	S115F	115	Missense	central	0	yes	12.485	0.000	EPSD	CCLE	7.780	Loss
AGC_Akt_AKT1_ST	P84103	SRSF3	P31749	AKT1	S115	P116A	116	Missense	proximal	1	no	12.485	12.566	EPSD	CCLE	7.780	Up-regulation
AGC_Akt_AKT1_ST	P84103	SRSF3	P31749	AKT1	S120	S115F	115	Missense	distal	-5	no	11.984	12.932	EPSD	CCLE	7.780	Up-regulation
AGC_Akt_AKT1_ST	P84103	SRSF3	P31749	AKT1	S120	P116A	116	Missense	distal	-4	no	11.984	11.998	EPSD	CCLE	7.780	Up-regulation
AGC_Akt_AKT1_ST	P84103	SRSF3	P31749	AKT1	S122	S115F	115	Missense	distal	-7	no	16.112	15.834	EPSD;PhosphoSitePlus	CCLE	7.780	Down-regulation
AGC_Akt_AKT1_ST	P84103	SRSF3	P31749	AKT1	S122	P116A	116	Missense	distal	-6	no	16.112	16.121	EPSD;PhosphoSitePlus	CCLE	7.780	Up-regulation
AGC_Akt_AKT1_ST	Q13188	STK3	P31749	AKT1	T117	I119T	119	Missense	proximal	2	no	13.333	13.915	EPSD;PhosphoSitePlus	CCLE	7.780	Up-regulation
AGC_Akt_AKT1_ST	Q13188	STK3	P31749	AKT1	T117	K116N	116	Missense	proximal	-1	no	13.333	13.308	EPSD;PhosphoSitePlus	CCLE	7.780	Down-regulation
AGC_Akt_AKT1_ST	Q92794	KAT6A	P31749	AKT1	S1136	D1141Y	1141	Missense	distal	5	no	8.489	8.520	EPSD	CCLE	7.780	Up-regulation
AGC_Akt_AKT1_ST	Q9UKV3	ACIN1	P31749	AKT1	S10	L17M	17	Missense	distal	7	no	8.812	8.820	EPSD	CCLE	7.780	Up-regulation
AGC_Akt_AKT1_ST	Q9UKV3	ACIN1	P31749	AKT1	T13	L17M	17	Missense	distal	4	no	8.479	8.454	EPSD	CCLE	7.780	Down-regulation
AGC_Akt_AKT1_ST	Q9UKV3	ACIN1	P31749	AKT1	S377	E373K	373	Missense	distal	-4	no	8.358	8.942	EPSD	CCLE	7.780	Up-regulation
AGC_Akt_AKT1_ST	Q9UKV3	ACIN1	P31749	AKT1	T855	S854N	854	Missense	proximal	-1	no	8.452	8.434	EPSD	CCLE	7.780	Down-regulation
AGC_Akt_AKT1_ST	Q9UKV3	ACIN1	P31749	AKT1	S983	S990P	990	Missense	distal	7	no	12.353	12.295	EPSD	CCLE	7.780	Down-regulation
AGC_Akt_AKT1_ST	Q9UKV3	ACIN1	P31749	AKT1	T1159	R1163H	1163	Missense	distal	4	no	11.318	11.502	EPSD	CCLE	7.780	Up-regulation
AGC_Akt_AKT1_ST	Q9UKV3	ACIN1	P31749	AKT1	S1161	R1163H	1163	Missense	proximal	2	no	14.927	14.566	EPSD	CCLE	7.780	Down-regulation
AGC_Akt_AKT1_ST	Q9UKV3	ACIN1	P31749	AKT1	S1284	D1288N	1288	Missense	distal	4	no	14.748	14.633	EPSD	CCLE	7.780	Down-regulation
AGC_Akt_AKT1_ST	Q9UKV3	ACIN1	P31749	AKT1	S1284	R1285Q	1285	Missense	proximal	1	no	14.748	14.453	EPSD	CCLE	7.780	Down-regulation
AGC_Akt_AKT1_ST	Q07352	ZFP36L1	P31749	AKT1	T148	R149H	149	Missense	proximal	1	no	10.497	10.174	EPSD	CCLE	7.780	Down-regulation
AGC_Akt_AKT1_ST	Q14315	FLNC	P31749	AKT1	T423	V424M	424	Missense	proximal	1	no	9.759	9.697	EPSD	CCLE	7.780	Down-regulation
AGC_Akt_AKT1_ST	Q14315	FLNC	P31749	AKT1	T1829	Y1826H	1826	Missense	distal	-3	no	5.589	8.480	EPSD	CCLE	7.780	Gain
AGC_Akt_AKT1_ST	Q14315	FLNC	P31749	AKT1	S2646	G2644E	2644	Missense	proximal	-2	no	8.723	9.009	EPSD	CCLE	7.780	Up-regulation
AGC_Akt_AKT1_ST	Q15027	ACAP1	P31749	AKT1	S459	V452A	452	Missense	distal	-7	no	7.976	8.104	EPSD	CCLE	7.780	Up-regulation
AGC_Akt_AKT1_ST	Q13107	USP4	P31749	AKT1	S445	N438K	438	Missense	distal	-7	no	14.403	14.560	PhosphoSitePlus	CCLE	7.780	Up-regulation
AGC_Akt_AKT1_ST	Q13107	USP4	P31749	AKT1	S947	S948C	948	Missense	proximal	1	no	12.260	11.877	EPSD	CCLE	7.780	Down-regulation
AGC_Akt_AKT1_ST	P03372	ESR1	P31749	AKT1	S236	A239D	239	Missense	distal	3	no	13.602	13.548	EPSD	CCLE	7.780	Down-regulation
AGC_Akt_AKT1_ST	Q12778	FOXO1	P31749	AKT1	S319	S325T	325	Missense	distal	6	no	17.079	17.099	PhosphoSitePlus;EPSD	CCLE	7.780	Up-regulation
AGC_Akt_AKT1_ST	P24941	CDK2	P31749	AKT1	S53	E51D	51	Missense	proximal	-2	no	10.981	9.996	EPSD	CCLE	7.780	Down-regulation
AGC_Akt_AKT1_ST	P15056	BRAF	P31749	AKT1	S429	R435S	435	Missense	distal	6	no	17.215	17.217	EPSD;PhosphoSitePlus	CCLE	7.780	Up-regulation
AGC_Akt_AKT1_ST	P15056	BRAF	P31749	AKT1	S430	R435S	435	Missense	distal	5	no	8.153	8.146	EPSD	CCLE	7.780	Down-regulation
AGC_Akt_AKT1_ST	P15056	BRAF	P31749	AKT1	S431	R435S	435	Missense	distal	4	no	9.847	9.837	EPSD	CCLE	7.780	Down-regulation
AGC_Akt_AKT1_ST	P15056	BRAF	P31749	AKT1	T440	R435S	435	Missense	distal	-5	no	13.648	9.178	EPSD	CCLE	7.780	Down-regulation
AGC_Akt_AKT1_ST	P15056	BRAF	P31749	AKT1	S446	E451K	451	Missense	distal	5	no	11.248	11.282	EPSD	CCLE	7.780	Up-regulation
AGC_Akt_AKT1_ST	P15056	BRAF	P31749	AKT1	S447	E451K	451	Missense	distal	4	no	9.898	9.797	EPSD	CCLE	7.780	Down-regulation
AGC_Akt_AKT1_ST	P15056	BRAF	P31749	AKT1	S729	A728V	728	Missense	proximal	-1	no	11.274	11.260	EPSD	CCLE	7.780	Down-regulation
AGC_Akt_AKT1_ST	Q9Y2V2	CARHSP1	P31749	AKT1	S17	Q15E	15	Missense	proximal	-2	no	8.770	9.063	EPSD	CCLE	7.780	Up-regulation
AGC_Akt_AKT1_ST	Q9Y2V2	CARHSP1	P31749	AKT1	T50	V55L	55	Missense	distal	5	no	13.027	13.020	EPSD	CCLE	7.780	Down-regulation
AGC_Akt_AKT1_ST	Q9Y2V2	CARHSP1	P31749	AKT1	T50	R47W	47	Missense	distal	-3	no	13.027	4.087	EPSD	CCLE	7.780	Loss
AGC_Akt_AKT1_ST	Q9Y2V2	CARHSP1	P31749	AKT1	S52	V55L	55	Missense	distal	3	no	17.128	17.120	PhosphoSitePlus	CCLE	7.780	Down-regulation
AGC_Akt_AKT1_ST	Q9Y2V2	CARHSP1	P31749	AKT1	S52	R47W	47	Missense	distal	-5	no	17.128	11.608	PhosphoSitePlus	CCLE	7.780	Down-regulation
AGC_Akt_AKT1_ST	Q9Y2V2	CARHSP1	P31749	AKT1	T54	V55L	55	Missense	proximal	1	no	12.372	12.472	EPSD	CCLE	7.780	Up-regulation
AGC_Akt_AKT1_ST	Q9Y2V2	CARHSP1	P31749	AKT1	T54	R47W	47	Missense	distal	-7	no	12.372	11.949	EPSD	CCLE	7.780	Down-regulation
AGC_Akt_AKT1_ST	Q9Y2V2	CARHSP1	P31749	AKT1	T139	T135S	135	Missense	distal	-4	no	8.510	8.454	EPSD	CCLE	7.780	Down-regulation
AGC_Akt_AKT1_ST	Q9Y2V2	CARHSP1	P31749	AKT1	S141	T135S	135	Missense	distal	-6	no	8.201	8.170	EPSD	CCLE	7.780	Down-regulation
AGC_Akt_AKT1_ST	P53365	ARFIP2	P31749	AKT1	S72	R69C	69	Missense	distal	-3	no	12.451	6.277	EPSD	CCLE	7.780	Loss
AGC_Akt_AKT1_ST	P53365	ARFIP2	P31749	AKT1	S74	R69C	69	Missense	distal	-5	no	9.738	5.661	EPSD	CCLE	7.780	Loss
AGC_Akt_AKT1_ST	P53365	ARFIP2	P31749	AKT1	S260	A267T	267	Missense	distal	7	no	14.754	14.815	PhosphoSitePlus	CCLE	7.780	Up-regulation
AGC_Akt_AKT1_ST	P53365	ARFIP2	P31749	AKT1	S260	S260I	260	Missense	central	0	yes	14.754	0.000	PhosphoSitePlus	CCLE	7.780	Loss
AGC_Akt_AKT1_ST	Q14457	BECN1	P31749	AKT1	S90	S93N	93	Missense	distal	3	no	10.581	10.525	EPSD	CCLE	7.780	Down-regulation
AGC_Akt_AKT1_ST	P67809	YBX1	P31749	AKT1	T80	F85C	85	Missense	distal	5	no	9.901	9.855	EPSD	CCLE	7.780	Down-regulation
AGC_Akt_AKT1_ST	P67809	YBX1	P31749	AKT1	S102	S102I	102	Missense	central	0	yes	8.722	0.000	PhosphoSitePlus	CCLE	7.780	Loss
AGC_Akt_AKT1_ST	O14757	CHEK1	P31749	AKT1	S280	A273T	273	Missense	distal	-7	no	12.979	13.178	PhosphoSitePlus	CCLE	7.780	Up-regulation
AGC_Akt_AKT1_ST	O14757	CHEK1	P31749	AKT1	S280	T279A	279	Missense	proximal	-1	no	12.979	12.952	PhosphoSitePlus	CCLE	7.780	Down-regulation
AGC_Akt_AKT1_ST	Q13131	PRKAA1	P31749	AKT1	S496	S494L	494	Missense	proximal	-2	no	13.385	12.528	PhosphoSitePlus	CCLE	7.780	Down-regulation
AGC_Akt_AKT1_ST	Q13131	PRKAA1	P31749	AKT1	S496	S494W	494	Missense	proximal	-2	no	13.385	11.942	PhosphoSitePlus	CCLE	7.780	Down-regulation
AGC_Akt_AKT1_ST	Q13131	PRKAA1	P31749	AKT1	S498	S494L	494	Missense	distal	-4	no	9.782	8.658	EPSD	CCLE	7.780	Down-regulation
AGC_Akt_AKT1_ST	Q13131	PRKAA1	P31749	AKT1	S498	S494W	494	Missense	distal	-4	no	9.782	8.318	EPSD	CCLE	7.780	Down-regulation
AGC_Akt_AKT1_ST	Q9UQC2	GAB2	P31749	AKT1	S550	N557T	557	Missense	distal	7	no	8.746	8.791	EPSD	CCLE	7.780	Up-regulation
AGC_Akt_AKT1_ST	P23769	GATA2	P31749	AKT1	S276	G273R	273	Missense	distal	-3	no	4.422	11.178	EPSD	CCLE	7.780	Gain
AGC_Akt_AKT1_ST	Q05397	PTK2	P31749	AKT1	S239	A232S	232	Missense	distal	-7	no	10.719	10.869	EPSD	CCLE	7.780	Up-regulation
AGC_Akt_AKT1_ST	P54253	ATXN1	P31749	AKT1	S262	A261T	261	Missense	proximal	-1	no	12.639	12.666	EPSD	CCLE	7.780	Up-regulation
AGC_Akt_AKT1_ST	P54253	ATXN1	P31749	AKT1	S775	A768V	768	Missense	distal	-7	no	17.674	17.545	PhosphoSitePlus	CCLE	7.780	Down-regulation
AGC_Akt_AKT1_ST	Q9BRS8	LARP6	P31749	AKT1	S67	S63N	63	Missense	distal	-4	no	12.326	11.759	EPSD	CCLE	7.780	Down-regulation
AGC_Akt_AKT1_ST	Q9BRS8	LARP6	P31749	AKT1	T69	S63N	63	Missense	distal	-6	no	10.900	10.853	EPSD	CCLE	7.780	Down-regulation
AGC_Akt_AKT1_ST	P07550	ADRB2	P31749	AKT1	T68	E62D	62	Missense	distal	-6	no	8.233	8.161	EPSD	CCLE	7.780	Down-regulation
AGC_Akt_AKT1_ST	P07550	ADRB2	P31749	AKT1	S346	S345P	345	Missense	proximal	-1	no	13.056	13.027	PhosphoSitePlus	CCLE	7.780	Down-regulation
AGC_Akt_AKT1_ST	Q9H4A3	WNK1	P31749	AKT1	S10	G4A	4	Missense	distal	-6	no	8.025	8.050	EPSD	CCLE	7.780	Up-regulation
AGC_Akt_AKT1_ST	Q9H4A3	WNK1	P31749	AKT1	S11	G4A	4	Missense	distal	-7	no	8.753	8.790	EPSD	CCLE	7.780	Up-regulation
AGC_Akt_AKT1_ST	Q9H4A3	WNK1	P31749	AKT1	S185	K191N	191	Missense	distal	6	no	11.024	10.946	EPSD	CCLE	7.780	Down-regulation
AGC_Akt_AKT1_ST	Q9H4A3	WNK1	P31749	AKT1	S1105	R1103Q	1103	Missense	proximal	-2	no	9.494	8.982	EPSD	CCLE	7.780	Down-regulation
AGC_Akt_AKT1_ST	Q9H4A3	WNK1	P31749	AKT1	S1108	R1103Q	1103	Missense	distal	-5	no	9.070	4.842	EPSD	CCLE	7.780	Loss
AGC_Akt_AKT1_ST	Q9H4A3	WNK1	P31749	AKT1	S1110	R1103Q	1103	Missense	distal	-7	no	10.716	10.522	EPSD	CCLE	7.780	Down-regulation
AGC_Akt_AKT1_ST	Q9H4A3	WNK1	P31749	AKT1	S1110	R1117C	1117	Missense	distal	7	no	10.716	10.586	EPSD	CCLE	7.780	Down-regulation
AGC_Akt_AKT1_ST	Q9H4A3	WNK1	P31749	AKT1	S1116	R1117C	1117	Missense	proximal	1	no	10.085	9.556	EPSD	CCLE	7.780	Down-regulation
AGC_Akt_AKT1_ST	Q9H4A3	WNK1	P31749	AKT1	S1805	L1804V	1804	Missense	proximal	-1	no	13.675	13.669	EPSD	CCLE	7.780	Down-regulation
AGC_Akt_AKT1_ST	Q9NPC1	LTB4R2	P31749	AKT1	S246	G245C	245	Missense	proximal	-1	no	11.137	11.107	EPSD	CCLE	7.780	Down-regulation
AGC_Akt_AKT1_ST	Q9NPC1	LTB4R2	P31749	AKT1	S246	R252P	252	Missense	distal	6	no	11.137	11.045	EPSD	CCLE	7.780	Down-regulation
AGC_Akt_AKT1_ST	Q9NPC1	LTB4R2	P31749	AKT1	S342	G349S	349	Missense	distal	7	no	10.051	10.125	EPSD	CCLE	7.780	Up-regulation
AGC_Akt_AKT1_ST	Q9NPC1	LTB4R2	P31749	AKT1	T355	G349S	349	Missense	distal	-6	no	15.917	15.996	EPSD	CCLE	7.780	Up-regulation
AGC_Akt_AKT1_ST	P21333	FLNA	P31749	AKT1	S440	R443S	443	Missense	distal	3	no	11.952	11.968	EPSD	CCLE	7.780	Up-regulation
AGC_Akt_AKT1_ST	P21333	FLNA	P31749	AKT1	T790	A797T	797	Missense	distal	7	no	8.600	8.661	EPSD	CCLE	7.780	Up-regulation
AGC_Akt_AKT1_ST	P21333	FLNA	P31749	AKT1	T790	D795H	795	Missense	distal	5	no	8.600	8.608	EPSD	CCLE	7.780	Up-regulation
AGC_Akt_AKT1_ST	P21333	FLNA	P31749	AKT1	S1081	Q1078R	1078	Missense	distal	-3	no	2.517	9.729	EPSD	CCLE	7.780	Gain
AGC_Akt_AKT1_ST	P30291	WEE1	P31749	AKT1	T69	P64S	64	Missense	distal	-5	no	12.015	11.555	EPSD	CCLE	7.780	Down-regulation
AGC_Akt_AKT1_ST	P78371	CCT2	P31749	AKT1	T134	T134M	134	Missense	central	0	yes	10.179	0.000	EPSD	CCLE	7.780	Loss
AGC_Akt_AKT1_ST	P78371	CCT2	P31749	AKT1	T379	G377V	377	Missense	proximal	-2	no	10.191	9.695	EPSD	CCLE	7.780	Down-regulation
AGC_Akt_AKT1_ST	P41279	MAP3K8	P31749	AKT1	S62	D57N	57	Missense	distal	-5	no	12.056	11.617	EPSD	CCLE	7.780	Down-regulation
AGC_Akt_AKT1_ST	P41279	MAP3K8	P31749	AKT1	S400	Q399H	399	Missense	proximal	-1	no	11.067	11.055	PhosphoSitePlus	CCLE	7.780	Down-regulation
AGC_Akt_AKT1_ST	Q96QB1	DLC1	P31749	AKT1	S354	M355V	355	Missense	proximal	1	no	14.062	14.124	EPSD	CCLE	7.780	Up-regulation
AGC_Akt_AKT1_ST	Q96QB1	DLC1	P31749	AKT1	S354	R349S	349	Missense	distal	-5	no	14.062	9.592	EPSD	CCLE	7.780	Down-regulation
AGC_Akt_AKT1_ST	Q96QB1	DLC1	P31749	AKT1	S548	R549W	549	Missense	proximal	1	no	8.566	8.273	EPSD	CCLE	7.780	Down-regulation
AGC_Akt_AKT1_ST	Q96QB1	DLC1	P31749	AKT1	S598	V594I	594	Missense	distal	-4	no	10.137	9.850	EPSD	CCLE	7.780	Down-regulation
AGC_Akt_AKT1_ST	Q96QB1	DLC1	P31749	AKT1	T600	V594I	594	Missense	distal	-6	no	8.833	8.788	EPSD	CCLE	7.780	Down-regulation
AGC_Akt_AKT1_ST	Q96QB1	DLC1	P31749	AKT1	S830	S826R	826	Missense	distal	-4	no	7.909	7.994	EPSD	CCLE	7.780	Up-regulation
AGC_Akt_AKT1_ST	Q96QB1	DLC1	P31749	AKT1	S856	L851I	851	Missense	distal	-5	no	11.907	11.466	EPSD	CCLE	7.780	Down-regulation
AGC_Akt_AKT1_ST	Q96QB1	DLC1	P31749	AKT1	S857	L851I	851	Missense	distal	-6	no	9.035	8.965	EPSD	CCLE	7.780	Down-regulation
AGC_Akt_AKT1_ST	Q96QB1	DLC1	P31749	AKT1	S1244	N1243K	1243	Missense	proximal	-1	no	12.859	12.883	EPSD	CCLE	7.780	Up-regulation
AGC_Akt_AKT1_ST	P26373	RPL13	P31749	AKT1	S106	N113S	113	Missense	distal	7	no	15.515	15.550	PhosphoSitePlus	CCLE	7.780	Up-regulation
AGC_Akt_AKT1_ST	P26373	RPL13	P31749	AKT1	S132	S139G	139	Missense	distal	7	no	11.763	11.690	EPSD	CCLE	7.780	Down-regulation
AGC_Akt_AKT1_ST	Q92793	CREBBP	P31749	AKT1	T974	P975L	975	Missense	proximal	1	no	10.364	10.618	EPSD	CCLE	7.780	Up-regulation
AGC_Akt_AKT1_ST	Q92793	CREBBP	P31749	AKT1	S1767	Q1760E	1760	Missense	distal	-7	no	7.818	7.806	EPSD	CCLE	7.780	Down-regulation
AGC_Akt_AKT1_ST	Q92793	CREBBP	P31749	AKT1	S1791	N1787H	1787	Missense	distal	-4	no	10.203	9.797	EPSD	CCLE	7.780	Down-regulation
AGC_Akt_AKT1_ST	Q92793	CREBBP	P31749	AKT1	T1931	Q1928E	1928	Missense	distal	-3	no	8.972	9.612	EPSD	CCLE	7.780	Up-regulation
AGC_Akt_AKT1_ST	P08670	VIM	P31749	AKT1	S7	S8P	8	Missense	proximal	1	no	12.841	12.686	EPSD	CCLE	7.780	Down-regulation
AGC_Akt_AKT1_ST	P08670	VIM	P31749	AKT1	S9	S8P	8	Missense	proximal	-1	no	10.359	10.330	EPSD	CCLE	7.780	Down-regulation
AGC_Akt_AKT1_ST	P08670	VIM	P31749	AKT1	S39	Y38H	38	Missense	proximal	-1	no	11.642	11.634	PhosphoSitePlus	CCLE	7.780	Down-regulation
AGC_Akt_AKT1_ST	P08670	VIM	P31749	AKT1	S72	G76E	76	Missense	distal	4	no	10.158	10.063	EPSD	CCLE	7.780	Down-regulation
AGC_Akt_AKT1_ST	Q7L5N1	COPS6	P31749	AKT1	S60	V66M	66	Missense	distal	6	no	9.584	9.599	PhosphoSitePlus	CCLE	7.780	Up-regulation
AGC_Akt_AKT1_ST	Q16763	UBE2S	P31749	AKT1	T152	R147Q	147	Missense	distal	-5	no	13.745	9.517	PhosphoSitePlus	CCLE	7.780	Down-regulation
AGC_Akt_AKT1_ST	Q96F86	EDC3	P31749	AKT1	T300	H297R	297	Missense	distal	-3	no	7.002	11.701	EPSD	CCLE	7.780	Gain
AGC_Akt_AKT1_ST	Q96F86	EDC3	P31749	AKT1	T308	E302K	302	Missense	distal	-6	no	8.418	8.485	EPSD	CCLE	7.780	Up-regulation
AGC_Akt_AKT1_ST	P14598	NCF1	P31749	AKT1	S328	R326H	326	Missense	proximal	-2	no	11.919	11.058	PhosphoSitePlus;EPSD	CCLE	7.780	Down-regulation
AGC_Akt_AKT1_ST	P14598	NCF1	P31749	AKT1	S359	R354L	354	Missense	distal	-5	no	8.011	3.885	EPSD	CCLE	7.780	Loss
AGC_Akt_AKT1_ST	P14598	NCF1	P31749	AKT1	S359	Q357H	357	Missense	proximal	-2	no	8.011	7.663	EPSD	CCLE	7.780	Loss
AGC_Akt_AKT1_ST	P05455	SSB	P31749	AKT1	S366	A365T	365	Missense	proximal	-1	no	8.048	8.075	EPSD	CCLE	7.780	Up-regulation
AGC_Akt_AKT1_ST	P20749	BCL3	P31749	AKT1	S41	P42L	42	Missense	proximal	1	no	13.310	13.564	PhosphoSitePlus	CCLE	7.780	Up-regulation
AGC_Akt_AKT1_ST	P20749	BCL3	P31749	AKT1	S382	R388H	388	Missense	distal	6	no	9.514	9.395	EPSD	CCLE	7.780	Down-regulation
AGC_Akt_AKT1_ST	P20749	BCL3	P31749	AKT1	S448	G453D	453	Missense	distal	5	no	9.964	9.953	EPSD	CCLE	7.780	Down-regulation
AGC_Akt_AKT1_ST	Q5UE93	PIK3R6	P31749	AKT1	S217	R212G	212	Missense	distal	-5	no	9.559	5.494	EPSD	CCLE	7.780	Loss
AGC_Akt_AKT1_ST	Q5UE93	PIK3R6	P31749	AKT1	S401	D403G	403	Missense	proximal	2	no	9.797	10.063	EPSD	CCLE	7.780	Up-regulation
AGC_Akt_AKT1_ST	Q5UE93	PIK3R6	P31749	AKT1	S401	S401G	401	Missense	central	0	yes	9.797	0.000	EPSD	CCLE	7.780	Loss
AGC_Akt_AKT1_ST	Q5UE93	PIK3R6	P31749	AKT1	T442	F445S	445	Missense	distal	3	no	8.819	8.918	EPSD	CCLE	7.780	Up-regulation
AGC_Akt_AKT1_ST	Q96J02	ITCH	P31749	AKT1	T218	D222H	222	Missense	distal	4	no	10.607	10.578	EPSD	CCLE	7.780	Down-regulation
AGC_Akt_AKT1_ST	Q96J02	ITCH	P31749	AKT1	T385	F380V	380	Missense	distal	-5	no	11.921	11.128	EPSD	CCLE	7.780	Down-regulation
AGC_Akt_AKT1_ST	P0DMV8	HSPA1A	P31749	AKT1	S254	R258Q	258	Missense	distal	4	no	7.692	7.815	EPSD	CCLE	7.780	Gain
AGC_Akt_AKT1_ST	P0DMV8	HSPA1A	P31749	AKT1	T265	R258Q	258	Missense	distal	-7	no	10.358	10.163	EPSD	CCLE	7.780	Down-regulation
AGC_Akt_AKT1_ST	O15360	FANCA	P31749	AKT1	S858	Q851H	851	Missense	distal	-7	no	8.747	8.640	EPSD	CCLE	7.780	Down-regulation
AGC_Akt_AKT1_ST	P53602	MVD	P31749	AKT1	S96	P101T	101	Missense	distal	5	no	16.708	16.761	PhosphoSitePlus	CCLE	7.780	Up-regulation
AGC_Akt_AKT1_ST	P53602	MVD	P31749	AKT1	S211	S218N	218	Missense	distal	7	no	8.779	8.744	EPSD	CCLE	7.780	Down-regulation
AGC_Akt_AKT1_ST	Q9BWT1	CDCA7	P31749	AKT1	S95	R92C	92	Missense	distal	-3	no	12.517	6.343	EPSD	CCLE	7.780	Loss
AGC_Akt_AKT1_ST	Q9BWT1	CDCA7	P31749	AKT1	T163	P159L	159	Missense	distal	-4	no	14.466	14.079	PhosphoSitePlus	CCLE	7.780	Down-regulation
AGC_Akt_AKT1_ST	Q13185	CBX3	P31749	AKT1	S93	E98G	98	Missense	distal	5	no	8.448	8.418	EPSD	CCLE	7.780	Down-regulation
AGC_Akt_AKT1_ST	Q13185	CBX3	P31749	AKT1	S95	E98G	98	Missense	distal	3	no	10.725	10.675	EPSD	CCLE	7.780	Down-regulation
AGC_Akt_AKT1_ST	Q13185	CBX3	P31749	AKT1	S97	E98G	98	Missense	proximal	1	no	9.435	9.226	EPSD	CCLE	7.780	Down-regulation
AGC_Akt_AKT1_ST	Q15942	ZYX	P31749	AKT1	S258	K265E	265	Missense	distal	7	no	8.170	8.136	EPSD	CCLE	7.780	Down-regulation
AGC_Akt_AKT1_ST	Q15942	ZYX	P31749	AKT1	S278	P275H	275	Missense	distal	-3	no	5.979	7.920	EPSD	CCLE	7.780	Gain
AGC_Akt_AKT1_ST	Q09472	EP300	P31749	AKT1	S89	M95T	95	Missense	distal	6	no	11.079	11.198	EPSD	CCLE	7.780	Up-regulation
AGC_Akt_AKT1_ST	Q09472	EP300	P31749	AKT1	S1295	F1288L	1288	Missense	distal	-7	no	11.851	11.895	EPSD	CCLE	7.780	Up-regulation
AGC_Akt_AKT1_ST	Q09472	EP300	P31749	AKT1	T1632	T1632M	1632	Missense	central	0	yes	7.981	0.000	EPSD	CCLE	7.780	Loss
AGC_Akt_AKT1_ST	Q09472	EP300	P31749	AKT1	S1734	R1737H	1737	Missense	distal	3	no	12.320	12.237	EPSD	CCLE	7.780	Down-regulation
AGC_Akt_AKT1_ST	P17302	GJA1	P31749	AKT1	S244	P246T	246	Missense	proximal	2	no	11.197	11.458	EPSD	CCLE	7.780	Up-regulation
AGC_Akt_AKT1_ST	Q9H4X1	RGCC	P31749	AKT1	S64	E58Q	58	Missense	distal	-6	no	11.300	11.296	EPSD	CCLE	7.780	Down-regulation
AGC_Akt_AKT1_ST	Q9H4X1	RGCC	P31749	AKT1	S64	A66T	66	Missense	proximal	2	no	11.300	11.601	EPSD	CCLE	7.780	Up-regulation
AGC_Akt_AKT1_ST	Q9H4X1	RGCC	P31749	AKT1	S64	S67G	67	Missense	distal	3	no	11.300	11.209	EPSD	CCLE	7.780	Down-regulation
AGC_Akt_AKT1_ST	Q9H4X1	RGCC	P31749	AKT1	S65	E58Q	58	Missense	distal	-7	no	12.435	12.447	EPSD	CCLE	7.780	Up-regulation
AGC_Akt_AKT1_ST	Q9H4X1	RGCC	P31749	AKT1	S65	A66T	66	Missense	proximal	1	no	12.435	12.702	EPSD	CCLE	7.780	Up-regulation
AGC_Akt_AKT1_ST	Q9H4X1	RGCC	P31749	AKT1	S65	S67G	67	Missense	proximal	2	no	12.435	12.103	EPSD	CCLE	7.780	Down-regulation
AGC_Akt_AKT1_ST	Q9H4X1	RGCC	P31749	AKT1	S67	A66T	66	Missense	proximal	-1	no	9.315	9.342	EPSD	CCLE	7.780	Up-regulation
AGC_Akt_AKT1_ST	Q9H4X1	RGCC	P31749	AKT1	S67	S67G	67	Missense	central	0	yes	9.315	0.000	EPSD	CCLE	7.780	Loss
AGC_Akt_AKT1_ST	O60331	PIP5K1C	P31749	AKT1	S666	D667N	667	Missense	proximal	1	no	8.594	8.718	EPSD	CCLE	7.780	Up-regulation
AGC_Akt_AKT1_ST	O60331	PIP5K1C	P31749	AKT1	S666	P660R	660	Missense	distal	-6	no	8.594	8.692	EPSD	CCLE	7.780	Up-regulation
AGC_Akt_AKT1_ST	Q12906	ILF3	P31749	AKT1	S647	R649Q	649	Missense	proximal	2	no	16.183	16.065	PhosphoSitePlus	CCLE	7.780	Down-regulation
AGC_Akt_AKT1_ST	Q12906	ILF3	P31749	AKT1	S647	R653H	653	Missense	distal	6	no	16.183	16.064	PhosphoSitePlus	CCLE	7.780	Down-regulation
AGC_Akt_AKT1_ST	Q12906	ILF3	P31749	AKT1	S820	G822D	822	Missense	proximal	2	no	8.780	8.513	EPSD	CCLE	7.780	Down-regulation
AGC_Akt_AKT1_ST	Q12906	ILF3	P31749	AKT1	S888	N890S	890	Missense	proximal	2	no	10.394	10.663	EPSD	CCLE	7.780	Up-regulation
AGC_Akt_AKT1_ST	Q12906	ILF3	P31749	AKT1	S888	Y893H	893	Missense	distal	5	no	10.394	10.371	EPSD	CCLE	7.780	Down-regulation
AGC_Akt_AKT1_ST	Q8IYJ3	SYTL1	P31749	AKT1	S468	S470G	470	Missense	proximal	2	no	9.752	9.420	EPSD	CCLE	7.780	Down-regulation
AGC_Akt_AKT1_ST	Q8IYJ3	SYTL1	P31749	AKT1	S470	S470G	470	Missense	central	0	yes	12.416	0.000	EPSD	CCLE	7.780	Loss
AGC_Akt_AKT1_ST	Q8WYL5	SSH1	P31749	AKT1	S237	P235T	235	Missense	proximal	-2	no	10.340	11.097	EPSD	CCLE	7.780	Up-regulation
AGC_Akt_AKT1_ST	Q8WYL5	SSH1	P31749	AKT1	S402	R399P	399	Missense	distal	-3	no	11.598	4.958	EPSD	CCLE	7.780	Loss
AGC_Akt_AKT1_ST	Q8WYL5	SSH1	P31749	AKT1	T430	R431C	431	Missense	proximal	1	no	12.426	11.898	EPSD	CCLE	7.780	Down-regulation
AGC_Akt_AKT1_ST	Q8WYL5	SSH1	P31749	AKT1	S696	E702D	702	Missense	distal	6	no	8.131	8.040	EPSD	CCLE	7.780	Down-regulation
AGC_Akt_AKT1_ST	O15111	CHUK	P31749	AKT1	T23	C30S	30	Missense	distal	7	no	13.896	14.018	PhosphoSitePlus	CCLE	7.780	Up-regulation
AGC_Akt_AKT1_ST	P54274	TERF1	P31749	AKT1	T24	M28I	28	Missense	distal	4	no	7.866	7.964	EPSD	CCLE	7.780	Up-regulation
AGC_Akt_AKT1_ST	Q86VP3	PACS2	P31749	AKT1	S349	P347S	347	Missense	proximal	-2	no	7.363	8.187	EPSD	CCLE	7.780	Gain
AGC_Akt_AKT1_ST	Q86VP3	PACS2	P31749	AKT1	S366	L360P	360	Missense	distal	-6	no	11.282	11.269	EPSD	CCLE	7.780	Down-regulation
AGC_Akt_AKT1_ST	Q86VP3	PACS2	P31749	AKT1	T412	G409R	409	Missense	distal	-3	no	5.326	12.082	EPSD	CCLE	7.780	Gain
AGC_Akt_AKT1_ST	Q86VP3	PACS2	P31749	AKT1	T414	G409R	409	Missense	distal	-5	no	5.173	9.237	EPSD	CCLE	7.780	Gain
AGC_Akt_AKT1_ST	Q86VP3	PACS2	P31749	AKT1	S416	G409R	409	Missense	distal	-7	no	7.792	8.034	EPSD	CCLE	7.780	Up-regulation
AGC_Akt_AKT1_ST	Q86VP3	PACS2	P31749	AKT1	S786	S782P	782	Missense	distal	-4	no	8.435	7.699	EPSD	CCLE	7.780	Loss
AGC_Akt_AKT1_ST	Q99490	AGAP2	P31749	AKT1	S146	G152D	152	Missense	distal	6	no	10.152	10.108	EPSD	CCLE	7.780	Down-regulation
AGC_Akt_AKT1_ST	Q99490	AGAP2	P31749	AKT1	S146	R141W	141	Missense	distal	-5	no	10.152	4.632	EPSD	CCLE	7.780	Loss
AGC_Akt_AKT1_ST	Q99490	AGAP2	P31749	AKT1	S147	G152D	152	Missense	distal	5	no	8.810	8.798	EPSD	CCLE	7.780	Down-regulation
AGC_Akt_AKT1_ST	Q99490	AGAP2	P31749	AKT1	S147	R141W	141	Missense	distal	-6	no	8.810	8.662	EPSD	CCLE	7.780	Down-regulation
AGC_Akt_AKT1_ST	Q99490	AGAP2	P31749	AKT1	S648	T647N	647	Missense	proximal	-1	no	13.167	13.143	EPSD	CCLE	7.780	Down-regulation
AGC_Akt_AKT1_ST	Q99490	AGAP2	P31749	AKT1	T839	R834M	834	Missense	distal	-5	no	11.095	6.573	EPSD	CCLE	7.780	Loss
AGC_Akt_AKT1_ST	Q99490	AGAP2	P31749	AKT1	S1178	A1185T	1185	Missense	distal	7	no	14.271	14.332	EPSD	CCLE	7.780	Up-regulation
AGC_Akt_AKT1_ST	Q99490	AGAP2	P31749	AKT1	S1181	A1185T	1185	Missense	distal	4	no	11.017	10.887	EPSD	CCLE	7.780	Down-regulation
AGC_Akt_AKT1_ST	Q8N6T7	SIRT6	P31749	AKT1	T337	E334K	334	Missense	distal	-3	no	7.818	9.869	EPSD	CCLE	7.780	Up-regulation
AGC_Akt_AKT1_ST	Q8N6T7	SIRT6	P31749	AKT1	S338	E334K	334	Missense	distal	-4	no	17.700	18.284	PhosphoSitePlus	CCLE	7.780	Up-regulation
AGC_Akt_AKT1_ST	P21453	S1PR1	P31749	AKT1	S355	P361H	361	Missense	distal	6	no	13.849	13.822	EPSD	CCLE	7.780	Down-regulation
AGC_Akt_AKT1_ST	Q9NWV8	BABAM1	P31749	AKT1	T27	A21V	21	Missense	distal	-6	no	11.107	11.087	EPSD	CCLE	7.780	Down-regulation
AGC_Akt_AKT1_ST	Q9NWV8	BABAM1	P31749	AKT1	T27	S29C	29	Missense	proximal	2	no	11.107	10.283	EPSD	CCLE	7.780	Down-regulation
AGC_Akt_AKT1_ST	Q9NWV8	BABAM1	P31749	AKT1	S29	S29C	29	Missense	central	0	yes	15.557	0.000	PhosphoSitePlus	CCLE	7.780	Loss
AGC_Akt_AKT1_ST	Q86TI0	TBC1D1	P31749	AKT1	T505	L512F	512	Missense	distal	7	no	12.351	12.344	EPSD	CCLE	7.780	Down-regulation
AGC_Akt_AKT1_ST	Q86TI0	TBC1D1	P31749	AKT1	S507	L512F	512	Missense	distal	5	no	9.996	9.990	EPSD	CCLE	7.780	Down-regulation
AGC_Akt_AKT1_ST	Q86TI0	TBC1D1	P31749	AKT1	S627	M623T	623	Missense	distal	-4	no	11.603	12.568	EPSD	CCLE	7.780	Up-regulation
AGC_Akt_AKT1_ST	Q86TI0	TBC1D1	P31749	AKT1	S627	V628L	628	Missense	proximal	1	no	11.603	11.703	EPSD	CCLE	7.780	Up-regulation
AGC_Akt_AKT1_ST	Q86TI0	TBC1D1	P31749	AKT1	S629	M623T	623	Missense	distal	-6	no	11.727	11.820	EPSD	CCLE	7.780	Up-regulation
AGC_Akt_AKT1_ST	Q86TI0	TBC1D1	P31749	AKT1	S629	V628L	628	Missense	proximal	-1	no	11.727	11.734	EPSD	CCLE	7.780	Up-regulation
AGC_Akt_AKT1_ST	Q86TI0	TBC1D1	P31749	AKT1	T716	K714R	714	Missense	proximal	-2	no	8.197	7.757	EPSD	CCLE	7.780	Loss
AGC_Akt_AKT1_ST	Q86TI0	TBC1D1	P31749	AKT1	S717	K714R	714	Missense	distal	-3	no	8.913	13.433	EPSD	CCLE	7.780	Up-regulation
AGC_Akt_AKT1_ST	Q86TI0	TBC1D1	P31749	AKT1	S1150	R1149W	1149	Missense	proximal	-1	no	11.421	11.361	EPSD	CCLE	7.780	Down-regulation
AGC_Akt_AKT1_ST	Q86TI0	TBC1D1	P31749	AKT1	S1154	R1149W	1149	Missense	distal	-5	no	11.797	6.277	EPSD	CCLE	7.780	Loss
AGC_Akt_AKT1_ST	Q9Y2I7	PIKFYVE	P31749	AKT1	S1042	S1042F	1042	Missense	central	0	yes	9.279	0.000	EPSD	CCLE	7.780	Loss
AGC_Akt_AKT1_ST	Q9Y4P1	ATG4B	P31749	AKT1	S383	E384K	384	Missense	proximal	1	no	8.846	9.009	EPSD	CCLE	7.780	Up-regulation
AGC_Akt_AKT1_ST	Q6R327	RICTOR	P31749	AKT1	S21	V15I	15	Missense	distal	-6	no	15.434	15.389	EPSD	CCLE	7.780	Down-regulation
AGC_Akt_AKT1_ST	Q6R327	RICTOR	P31749	AKT1	S1302	A1309T	1309	Missense	distal	7	no	13.316	13.377	EPSD	CCLE	7.780	Up-regulation
AGC_Akt_AKT1_ST	P45985	MAP2K4	P31749	AKT1	T78	H72Q	72	Missense	distal	-6	no	10.970	11.005	EPSD	CCLE	7.780	Up-regulation
AGC_Akt_AKT1_ST	Q8WX93	PALLD	P31749	AKT1	S125	R120M	120	Missense	distal	-5	no	8.726	4.203	EPSD	CCLE	7.780	Loss
AGC_Akt_AKT1_ST	Q8WX93	PALLD	P31749	AKT1	S192	E196Q	196	Missense	distal	4	no	12.748	12.804	EPSD	CCLE	7.780	Up-regulation
AGC_Akt_AKT1_ST	Q7Z6J0	SH3RF1	P31749	AKT1	T684	S679C	679	Missense	distal	-5	no	9.469	9.863	EPSD	CCLE	7.780	Up-regulation
AGC_Akt_AKT1_ST	Q7Z6J0	SH3RF1	P31749	AKT1	S800	A805T	805	Missense	distal	5	no	12.055	12.106	EPSD	CCLE	7.780	Up-regulation
AGC_Akt_AKT1_ST	Q8NCD3	HJURP	P31749	AKT1	T178	P179R	179	Missense	proximal	1	no	7.577	7.877	EPSD	CCLE	7.780	Gain
AGC_Akt_AKT1_ST	Q8NCD3	HJURP	P31749	AKT1	S182	P179R	179	Missense	distal	-3	no	4.319	10.958	EPSD	CCLE	7.780	Gain
AGC_Akt_AKT1_ST	Q8NCD3	HJURP	P31749	AKT1	T380	P381S	381	Missense	proximal	1	no	12.598	12.754	EPSD	CCLE	7.780	Up-regulation
AGC_Akt_AKT1_ST	Q8NCD3	HJURP	P31749	AKT1	S382	P381S	381	Missense	proximal	-1	no	10.087	10.116	EPSD	CCLE	7.780	Up-regulation
AGC_Akt_AKT1_ST	Q8NCD3	HJURP	P31749	AKT1	S563	P565T	565	Missense	proximal	2	no	7.562	7.824	EPSD	CCLE	7.780	Gain
AGC_Akt_AKT1_ST	P35568	IRS1	P31749	AKT1	S24	L19R	19	Missense	distal	-5	no	7.019	11.145	EPSD	CCLE	7.780	Gain
AGC_Akt_AKT1_ST	P35568	IRS1	P31749	AKT1	S268	S273L	273	Missense	distal	5	no	11.282	11.215	EPSD	CCLE	7.780	Down-regulation
AGC_Akt_AKT1_ST	P35568	IRS1	P31749	AKT1	S270	S273L	273	Missense	distal	3	no	14.918	14.820	EPSD	CCLE	7.780	Down-regulation
AGC_Akt_AKT1_ST	P35568	IRS1	P31749	AKT1	S272	S273L	273	Missense	proximal	1	no	12.914	13.013	EPSD	CCLE	7.780	Up-regulation
AGC_Akt_AKT1_ST	P35568	IRS1	P31749	AKT1	T305	R304H	304	Missense	proximal	-1	no	13.125	13.081	EPSD	CCLE	7.780	Down-regulation
AGC_Akt_AKT1_ST	P35568	IRS1	P31749	AKT1	T305	R302Q	302	Missense	distal	-3	no	13.125	5.914	EPSD	CCLE	7.780	Loss
AGC_Akt_AKT1_ST	P35568	IRS1	P31749	AKT1	S307	A314D	314	Missense	distal	7	no	16.317	16.291	EPSD	CCLE	7.780	Down-regulation
AGC_Akt_AKT1_ST	P35568	IRS1	P31749	AKT1	S307	R304H	304	Missense	distal	-3	no	16.317	11.618	EPSD	CCLE	7.780	Down-regulation
AGC_Akt_AKT1_ST	P35568	IRS1	P31749	AKT1	S307	R302Q	302	Missense	distal	-5	no	16.317	12.089	EPSD	CCLE	7.780	Down-regulation
AGC_Akt_AKT1_ST	P35568	IRS1	P31749	AKT1	T309	A314D	314	Missense	distal	5	no	9.758	9.735	EPSD	CCLE	7.780	Down-regulation
AGC_Akt_AKT1_ST	P35568	IRS1	P31749	AKT1	T309	R304H	304	Missense	distal	-5	no	9.758	6.663	EPSD	CCLE	7.780	Loss
AGC_Akt_AKT1_ST	P35568	IRS1	P31749	AKT1	T309	R302Q	302	Missense	distal	-7	no	9.758	9.564	EPSD	CCLE	7.780	Down-regulation
AGC_Akt_AKT1_ST	P35568	IRS1	P31749	AKT1	T525	P532S	532	Missense	distal	7	no	14.903	14.962	EPSD	CCLE	7.780	Up-regulation
AGC_Akt_AKT1_ST	P35568	IRS1	P31749	AKT1	S527	P532S	532	Missense	distal	5	no	16.468	16.521	EPSD	CCLE	7.780	Up-regulation
AGC_Akt_AKT1_ST	P35568	IRS1	P31749	AKT1	S574	T579I	579	Missense	distal	5	no	7.811	7.714	EPSD	CCLE	7.780	Loss
AGC_Akt_AKT1_ST	P35568	IRS1	P31749	AKT1	S574	V577M	577	Missense	distal	3	no	7.811	7.816	EPSD	CCLE	7.780	Up-regulation
AGC_Akt_AKT1_ST	P35568	IRS1	P31749	AKT1	T793	S795Y	795	Missense	proximal	2	no	10.368	9.996	EPSD	CCLE	7.780	Down-regulation
AGC_Akt_AKT1_ST	P35568	IRS1	P31749	AKT1	T793	L791P	791	Missense	proximal	-2	no	10.368	10.400	EPSD	CCLE	7.780	Up-regulation
AGC_Akt_AKT1_ST	P35568	IRS1	P31749	AKT1	S1100	S1105F	1105	Missense	distal	5	no	13.515	13.442	EPSD	CCLE	7.780	Down-regulation
AGC_Akt_AKT1_ST	P35568	IRS1	P31749	AKT1	S1101	S1105F	1105	Missense	distal	4	no	16.825	17.021	EPSD	CCLE	7.780	Up-regulation
AGC_Akt_AKT1_ST	P35568	IRS1	P31749	AKT1	T1103	S1105F	1105	Missense	proximal	2	no	7.892	7.315	EPSD	CCLE	7.780	Loss
AGC_Akt_AKT1_ST	P35568	IRS1	P31749	AKT1	S1142	E1136K	1136	Missense	distal	-6	no	8.598	8.665	EPSD	CCLE	7.780	Up-regulation
AGC_Akt_AKT1_ST	P35568	IRS1	P31749	AKT1	S1143	E1136K	1136	Missense	distal	-7	no	12.388	12.580	EPSD	CCLE	7.780	Up-regulation
AGC_Akt_AKT1_ST	Q16875	PFKFB3	P31749	AKT1	S211	D207G	207	Missense	distal	-4	no	9.597	10.156	EPSD	CCLE	7.780	Up-regulation
AGC_Akt_AKT1_ST	O15519	CFLAR	P31749	AKT1	S248	K245E	245	Missense	distal	-3	no	9.004	6.952	EPSD	CCLE	7.780	Loss
AGC_Akt_AKT1_ST	P26358	DNMT1	P31749	AKT1	T12	V10M	10	Missense	proximal	-2	no	11.540	11.891	EPSD	CCLE	7.780	Up-regulation
AGC_Akt_AKT1_ST	P26358	DNMT1	P31749	AKT1	S141	T137R	137	Missense	distal	-4	no	10.414	10.444	EPSD	CCLE	7.780	Up-regulation
AGC_Akt_AKT1_ST	P26358	DNMT1	P31749	AKT1	S143	T137R	137	Missense	distal	-6	no	11.970	11.973	PhosphoSitePlus	CCLE	7.780	Up-regulation
AGC_Akt_AKT1_ST	P26358	DNMT1	P31749	AKT1	T208	E211A	211	Missense	distal	3	no	12.194	12.178	EPSD	CCLE	7.780	Down-regulation
AGC_Akt_AKT1_ST	P26358	DNMT1	P31749	AKT1	S209	E211A	211	Missense	proximal	2	no	15.580	15.393	EPSD	CCLE	7.780	Down-regulation
AGC_Akt_AKT1_ST	P26358	DNMT1	P31749	AKT1	S227	E221V	221	Missense	distal	-6	no	9.927	9.898	EPSD	CCLE	7.780	Down-regulation
AGC_Akt_AKT1_ST	P26358	DNMT1	P31749	AKT1	S288	K291E	291	Missense	distal	3	no	7.827	7.784	EPSD	CCLE	7.780	Down-regulation
AGC_Akt_AKT1_ST	P26358	DNMT1	P31749	AKT1	S288	K285Q	285	Missense	distal	-3	no	7.827	5.136	EPSD	CCLE	7.780	Loss
AGC_Akt_AKT1_ST	P26358	DNMT1	P31749	AKT1	T327	T333M	333	Missense	distal	6	no	11.335	11.216	EPSD	CCLE	7.780	Down-regulation
AGC_Akt_AKT1_ST	P26358	DNMT1	P31749	AKT1	T328	K335R	335	Missense	distal	7	no	16.306	16.313	EPSD	CCLE	7.780	Up-regulation
AGC_Akt_AKT1_ST	P26358	DNMT1	P31749	AKT1	T328	T333M	333	Missense	distal	5	no	16.306	16.249	EPSD	CCLE	7.780	Down-regulation
AGC_Akt_AKT1_ST	P26358	DNMT1	P31749	AKT1	T342	K335R	335	Missense	distal	-7	no	11.100	11.113	EPSD	CCLE	7.780	Up-regulation
AGC_Akt_AKT1_ST	P26358	DNMT1	P31749	AKT1	S549	S549F	549	Missense	central	0	yes	8.532	0.000	EPSD	CCLE	7.780	Loss
AGC_Akt_AKT1_ST	P26358	DNMT1	P31749	AKT1	S878	A874T	874	Missense	distal	-4	no	10.775	11.553	EPSD	CCLE	7.780	Up-regulation
AGC_Akt_AKT1_ST	P26358	DNMT1	P31749	AKT1	S1095	P1099S	1099	Missense	distal	4	no	8.006	7.850	EPSD	CCLE	7.780	Down-regulation
AGC_Akt_AKT1_ST	P15976	GATA1	P31749	AKT1	S116	P111L	111	Missense	distal	-5	no	12.092	11.976	EPSD	CCLE	7.780	Down-regulation
AGC_Akt_AKT1_ST	P15976	GATA1	P31749	AKT1	S310	R317W	317	Missense	distal	7	no	17.117	17.019	PhosphoSitePlus	CCLE	7.780	Down-regulation
AGC_Akt_AKT1_ST	P15976	GATA1	P31749	AKT1	S319	R317W	317	Missense	proximal	-2	no	10.053	8.799	EPSD	CCLE	7.780	Down-regulation
AGC_Akt_AKT1_ST	P15976	GATA1	P31749	AKT1	S319	G322E	322	Missense	distal	3	no	10.053	10.103	EPSD	CCLE	7.780	Up-regulation
AGC_Akt_AKT1_ST	P15976	GATA1	P31749	AKT1	S320	R317W	317	Missense	distal	-3	no	13.443	4.502	EPSD	CCLE	7.780	Loss
AGC_Akt_AKT1_ST	P15976	GATA1	P31749	AKT1	S320	G322E	322	Missense	proximal	2	no	13.443	13.586	EPSD	CCLE	7.780	Up-regulation
AGC_Akt_AKT1_ST	Q99502	EYA1	P31749	AKT1	S299	R306W	306	Missense	distal	7	no	16.579	16.481	PhosphoSitePlus	CCLE	7.780	Down-regulation
AGC_Akt_AKT1_ST	Q99502	EYA1	P31749	AKT1	S314	D320H	320	Missense	distal	6	no	7.980	8.009	EPSD	CCLE	7.780	Up-regulation
AGC_Akt_AKT1_ST	P17542	TAL1	P31749	AKT1	T90	V88M	88	Missense	proximal	-2	no	14.475	14.826	PhosphoSitePlus	CCLE	7.780	Up-regulation
AGC_Akt_AKT1_ST	P17542	TAL1	P31749	AKT1	S122	P124S	124	Missense	proximal	2	no	7.959	8.296	EPSD	CCLE	7.780	Up-regulation
AGC_Akt_AKT1_ST	P17542	TAL1	P31749	AKT1	S122	G116S	116	Missense	distal	-6	no	7.959	8.039	EPSD	CCLE	7.780	Up-regulation
AGC_Akt_AKT1_ST	P17542	TAL1	P31749	AKT1	S139	S146T	146	Missense	distal	7	no	9.657	9.667	EPSD	CCLE	7.780	Up-regulation
AGC_Akt_AKT1_ST	Q92934	BAD	P31749	AKT1	S25	S32L	32	Missense	distal	7	no	8.979	8.913	EPSD	CCLE	7.780	Down-regulation
AGC_Akt_AKT1_ST	Q92934	BAD	P31749	AKT1	S75	H73Q	73	Missense	proximal	-2	no	15.295	15.644	EPSD	CCLE	7.780	Up-regulation
AGC_Akt_AKT1_ST	Q92934	BAD	P31749	AKT1	S75	R70W	70	Missense	distal	-5	no	15.295	9.775	EPSD	CCLE	7.780	Down-regulation
AGC_Akt_AKT1_ST	P09651	HNRNPA1	P31749	AKT1	S182	K179R	179	Missense	distal	-3	no	8.643	13.163	EPSD	CCLE	7.780	Up-regulation
AGC_Akt_AKT1_ST	P09651	HNRNPA1	P31749	AKT1	S182	E185Q	185	Missense	distal	3	no	8.643	8.611	EPSD	CCLE	7.780	Down-regulation
AGC_Akt_AKT1_ST	P09651	HNRNPA1	P31749	AKT1	S197	N201K	201	Missense	distal	4	no	10.758	10.626	EPSD	CCLE	7.780	Down-regulation
AGC_Akt_AKT1_ST	P09651	HNRNPA1	P31749	AKT1	S199	N201K	201	Missense	proximal	2	no	17.470	17.755	PhosphoSitePlus	CCLE	7.780	Up-regulation
AGC_Akt_AKT1_ST	P84022	SMAD3	P31749	AKT1	T388	Q387H	387	Missense	proximal	-1	no	10.153	10.141	EPSD	CCLE	7.780	Down-regulation
AGC_Akt_AKT1_ST	P18031	PTPN1	P31749	AKT1	S50	P51S	51	Missense	proximal	1	no	15.185	15.340	PhosphoSitePlus	CCLE	7.780	Up-regulation
AGC_Akt_AKT1_ST	P18031	PTPN1	P31749	AKT1	T224	A228T	228	Missense	distal	4	no	9.882	9.753	EPSD	CCLE	7.780	Down-regulation
AGC_Akt_AKT1_ST	P68400	CSNK2A1	P31749	AKT1	T13	T13I	13	Missense	central	0	yes	15.151	0.000	PhosphoSitePlus	CCLE	7.780	Loss
AGC_Akt_AKT1_ST	P68400	CSNK2A1	P31749	AKT1	S194	K198R	198	Missense	distal	4	no	10.046	10.079	EPSD	CCLE	7.780	Up-regulation
AGC_Akt_AKT1_ST	P68400	CSNK2A1	P31749	AKT1	S336	M339I	339	Missense	distal	3	no	11.358	11.312	EPSD	CCLE	7.780	Down-regulation
AGC_Akt_AKT1_ST	P68400	CSNK2A1	P31749	AKT1	S338	M339I	339	Missense	proximal	1	no	9.548	9.362	EPSD	CCLE	7.780	Down-regulation
AGC_Akt_AKT1_ST	Q96HP0	DOCK6	P31749	AKT1	S30	R27Q	27	Missense	distal	-3	no	13.110	5.899	EPSD	CCLE	7.780	Loss
AGC_Akt_AKT1_ST	Q96HP0	DOCK6	P31749	AKT1	S176	S169P	169	Missense	distal	-7	no	13.373	13.179	EPSD	CCLE	7.780	Down-regulation
AGC_Akt_AKT1_ST	Q96HP0	DOCK6	P31749	AKT1	S189	A188T	188	Missense	proximal	-1	no	8.651	8.678	EPSD	CCLE	7.780	Up-regulation
AGC_Akt_AKT1_ST	Q96HP0	DOCK6	P31749	AKT1	S439	S439R	439	Missense	central	0	yes	9.361	0.000	EPSD	CCLE	7.780	Loss
AGC_Akt_AKT1_ST	Q96HP0	DOCK6	P31749	AKT1	S872	R869L	869	Missense	distal	-3	no	11.378	4.384	EPSD	CCLE	7.780	Loss
AGC_Akt_AKT1_ST	Q96HP0	DOCK6	P31749	AKT1	S1073	A1068V	1068	Missense	distal	-5	no	8.260	7.800	EPSD	CCLE	7.780	Down-regulation
AGC_Akt_AKT1_ST	Q96HP0	DOCK6	P31749	AKT1	S1194	R1189W	1189	Missense	distal	-5	no	15.967	10.447	PhosphoSitePlus	CCLE	7.780	Down-regulation
AGC_Akt_AKT1_ST	P22736	NR4A1	P31749	AKT1	T174	R171P	171	Missense	distal	-3	no	9.744	3.105	EPSD	CCLE	7.780	Loss
AGC_Akt_AKT1_ST	P42858	HTT	P31749	AKT1	S621	S620C	620	Missense	proximal	-1	no	11.834	11.773	EPSD	CCLE	7.780	Down-regulation
AGC_Akt_AKT1_ST	P42858	HTT	P31749	AKT1	S1111	E1114A	1114	Missense	distal	3	no	9.187	9.170	EPSD	CCLE	7.780	Down-regulation
AGC_Akt_AKT1_ST	P42858	HTT	P31749	AKT1	T2455	F2449L	2449	Missense	distal	-6	no	8.834	8.858	EPSD	CCLE	7.780	Up-regulation
AGC_Akt_AKT1_ST	P42858	HTT	P31749	AKT1	S2548	G2552R	2552	Missense	distal	4	no	11.391	11.228	EPSD	CCLE	7.780	Down-regulation
AGC_Akt_AKT1_ST	P05787	KRT8	P31749	AKT1	S315	E320K	320	Missense	distal	5	no	10.926	10.960	EPSD	CCLE	7.780	Up-regulation
AGC_Akt_AKT1_ST	P05787	KRT8	P31749	AKT1	S457	S451F	451	Missense	distal	-6	no	13.915	13.840	EPSD	CCLE	7.780	Down-regulation
AGC_Akt_AKT1_ST	P05787	KRT8	P31749	AKT1	S458	S451F	451	Missense	distal	-7	no	7.870	7.592	EPSD	CCLE	7.780	Loss
AGC_Akt_AKT1_ST	Q04912	MST1R	P31749	AKT1	S1056	P1050S	1050	Missense	distal	-6	no	10.291	10.355	EPSD	CCLE	7.780	Up-regulation
AGC_Akt_AKT1_ST	P63000	RAC1	P31749	AKT1	T167	Q162R	162	Missense	distal	-5	no	4.363	8.591	EPSD	CCLE	7.780	Gain
AGC_Akt_AKT1_ST	P04792	HSPB1	P31749	AKT1	S82	S78T	78	Missense	distal	-4	no	12.296	12.352	PhosphoSitePlus	CCLE	7.780	Up-regulation
AGC_Akt_AKT1_ST	P53804	TTC3	P31749	AKT1	S759	I752V	752	Missense	distal	-7	no	8.002	8.097	EPSD	CCLE	7.780	Up-regulation
AGC_Akt_AKT1_ST	P53804	TTC3	P31749	AKT1	S1915	P1919L	1919	Missense	distal	4	no	9.870	9.903	EPSD	CCLE	7.780	Up-regulation
AGC_Akt_AKT1_ST	P53804	TTC3	P31749	AKT1	S1927	P1928L	1928	Missense	proximal	1	no	8.475	8.729	EPSD	CCLE	7.780	Up-regulation
AGC_Akt_AKT1_ST	P56270	MAZ	P31749	AKT1	S222	P221T	221	Missense	proximal	-1	no	10.247	10.282	EPSD	CCLE	7.780	Up-regulation
AGC_Akt_AKT1_ST	P56270	MAZ	P31749	AKT1	T385	K391N	391	Missense	distal	6	no	14.332	14.254	PhosphoSitePlus	CCLE	7.780	Down-regulation
AGC_Akt_AKT1_ST	P09601	HMOX1	P31749	AKT1	S8	D7G	7	Missense	proximal	-1	no	9.807	9.825	EPSD	CCLE	7.780	Up-regulation
AGC_Akt_AKT1_ST	P09601	HMOX1	P31749	AKT1	S231	Q228H	228	Missense	distal	-3	no	5.700	8.213	EPSD	CCLE	7.780	Gain
AGC_Akt_AKT1_ST	Q13009	TIAM1	P31749	AKT1	S170	R177Q	177	Missense	distal	7	no	9.616	9.560	EPSD	CCLE	7.780	Down-regulation
AGC_Akt_AKT1_ST	Q13009	TIAM1	P31749	AKT1	S172	R177Q	177	Missense	distal	5	no	13.600	13.549	EPSD	CCLE	7.780	Down-regulation
AGC_Akt_AKT1_ST	Q13009	TIAM1	P31749	AKT1	S224	R221W	221	Missense	distal	-3	no	9.607	0.667	EPSD	CCLE	7.780	Loss
AGC_Akt_AKT1_ST	Q13009	TIAM1	P31749	AKT1	S298	C296S	296	Missense	proximal	-2	no	6.538	8.191	EPSD	CCLE	7.780	Gain
AGC_Akt_AKT1_ST	Q13009	TIAM1	P31749	AKT1	T319	A325V	325	Missense	distal	6	no	11.997	11.966	EPSD	CCLE	7.780	Down-regulation
AGC_Akt_AKT1_ST	Q13009	TIAM1	P31749	AKT1	T319	T320A	320	Missense	proximal	1	no	11.997	11.730	EPSD	CCLE	7.780	Down-regulation
AGC_Akt_AKT1_ST	Q13009	TIAM1	P31749	AKT1	T320	A325V	325	Missense	distal	5	no	10.112	10.103	EPSD	CCLE	7.780	Down-regulation
AGC_Akt_AKT1_ST	Q13009	TIAM1	P31749	AKT1	T320	T320A	320	Missense	central	0	yes	10.112	0.000	EPSD	CCLE	7.780	Loss
AGC_Akt_AKT1_ST	Q13009	TIAM1	P31749	AKT1	S1437	A1431V	1431	Missense	distal	-6	no	12.334	12.314	EPSD	CCLE	7.780	Down-regulation
AGC_Akt_AKT1_ST	Q7Z5H3	ARHGAP22	P31749	AKT1	S476	G477E	477	Missense	proximal	1	no	12.616	12.825	EPSD	CCLE	7.780	Up-regulation
TK_Src_SrcB_LYN_Y	P00519	ABL1	P07948	LYN	Y115	P112S	112	Missense	distal	-3	no	4.726	4.563	EPSD;PhosphoSitePlus	CCLE	1.526	Down-regulation
TK_Src_SrcB_LYN_Y	P00519	ABL1	P07948	LYN	Y128	R134C	134	Missense	distal	6	no	3.089	2.626	EPSD;PhosphoSitePlus	CCLE	1.526	Down-regulation
TK_Src_SrcB_LYN_Y	P00519	ABL1	P07948	LYN	Y139	R134C	134	Missense	distal	-5	no	5.477	4.893	EPSD;PhosphoSitePlus	CCLE	1.526	Down-regulation
TK_Src_SrcB_LYN_Y	P00519	ABL1	P07948	LYN	Y139	A137T	137	Missense	proximal	-2	no	5.477	5.765	EPSD;PhosphoSitePlus	CCLE	1.526	Up-regulation
TK_Src_SrcB_LYN_Y	P00519	ABL1	P07948	LYN	Y172	A179V	179	Missense	distal	7	no	5.321	5.342	EPSD;PhosphoSitePlus	CCLE	1.526	Up-regulation
TK_Src_SrcB_LYN_Y	P00519	ABL1	P07948	LYN	Y185	A179V	179	Missense	distal	-6	no	2.945	3.352	EPSD;PhosphoSitePlus	CCLE	1.526	Up-regulation
TK_Src_SrcB_LYN_Y	P00519	ABL1	P07948	LYN	Y215	Y215H	215	Missense	central	0	yes	1.584	0.000	EPSD;PhosphoSitePlus	CCLE	1.526	Loss
TK_Src_SrcB_LYN_Y	P00519	ABL1	P07948	LYN	Y226	T224I	224	Missense	proximal	-2	no	3.025	0.512	EPSD;PhosphoSitePlus	CCLE	1.526	Loss
TK_Src_SrcB_LYN_Y	P00519	ABL1	P07948	LYN	Y1064	G1060D	1060	Missense	distal	-4	no	2.096	3.407	EPSD	CCLE	1.526	Up-regulation
TK_Src_SrcB_LYN_Y	P25490	YY1	P07948	LYN	Y254	P261A	261	Missense	distal	7	no	2.433	2.458	EPSD;PhosphoSitePlus	CCLE	1.526	Up-regulation
TK_Src_SrcB_LYN_Y	O43823	AKAP8	P07948	LYN	Y170	N163S	163	Missense	distal	-7	no	1.993	1.864	EPSD;PhosphoSitePlus	CCLE	1.526	Down-regulation
TK_Src_SrcB_LYN_Y	O43823	AKAP8	P07948	LYN	Y229	L235P	235	Missense	distal	6	no	2.645	2.975	EPSD	CCLE	1.526	Up-regulation
TK_Src_SrcB_LYN_Y	O43823	AKAP8	P07948	LYN	Y229	R233Q	233	Missense	distal	4	no	2.645	2.525	EPSD	CCLE	1.526	Down-regulation
TK_Src_SrcB_LYN_Y	P11274	BCR	P07948	LYN	Y360	V353M	353	Missense	distal	-7	no	2.787	2.869	EPSD	CCLE	1.526	Up-regulation
TK_Src_SrcB_LYN_Y	P11274	BCR	P07948	LYN	Y360	S354F	354	Missense	distal	-6	no	2.787	2.890	EPSD	CCLE	1.526	Up-regulation
TK_Src_SrcB_LYN_Y	P11274	BCR	P07948	LYN	Y360	T358I	358	Missense	proximal	-2	no	2.787	0.273	EPSD	CCLE	1.526	Loss
TK_Src_SrcB_LYN_Y	P15391	CD19	P07948	LYN	Y378	D384E	384	Missense	distal	6	no	3.346	3.226	EPSD	CCLE	1.526	Down-regulation
TK_Src_SrcB_LYN_Y	Q13568	IRF5	P07948	LYN	Y313	R311C	311	Missense	proximal	-2	no	2.300	-2.429	PhosphoSitePlus;EPSD	CCLE	1.526	Loss
TK_Src_SrcB_LYN_Y	Q13568	IRF5	P07948	LYN	Y335	L334I	334	Missense	proximal	-1	no	5.361	6.375	EPSD;PhosphoSitePlus	CCLE	1.526	Up-regulation
TK_Src_SrcB_LYN_Y	Q13568	IRF5	P07948	LYN	Y335	C340Y	340	Missense	distal	5	no	5.361	3.175	EPSD;PhosphoSitePlus	CCLE	1.526	Down-regulation
TK_Src_SrcB_LYN_Y	P07948	LYN	P07948	LYN	Y397	Y397C	397	Missense	central	0	yes	8.295	0.000	PhosphoSitePlus;EPSD	CCLE	1.526	Loss
TK_Src_SrcB_LYN_Y	P07948	LYN	P07948	LYN	Y397	A403V	403	Missense	distal	6	no	8.295	8.335	PhosphoSitePlus;EPSD	CCLE	1.526	Up-regulation
TK_Src_SrcB_LYN_Y	Q14790	CASP8	P07948	LYN	Y448	V446A	446	Missense	proximal	-2	no	3.836	5.564	EPSD;PhosphoSitePlus	CCLE	1.526	Up-regulation
TK_Src_SrcB_LYN_Y	P29350	PTPN6	P07948	LYN	Y536	P542L	542	Missense	distal	6	no	5.656	5.327	PhosphoSitePlus	CCLE	1.526	Down-regulation
TK_Src_SrcB_LYN_Y	P29350	PTPN6	P07948	LYN	Y564	H568Y	568	Missense	distal	4	no	4.298	4.266	EPSD	CCLE	1.526	Down-regulation
TK_Src_SrcB_LYN_Y	P46527	CDKN1B	P07948	LYN	Y88	F87L	87	Missense	proximal	-1	no	4.687	4.291	PhosphoSitePlus	CCLE	1.526	Down-regulation
TK_Src_SrcB_LYN_Y	P46527	CDKN1B	P07948	LYN	Y88	Y89C	89	Missense	proximal	1	no	4.687	4.696	PhosphoSitePlus	CCLE	1.526	Up-regulation
TK_Src_SrcB_LYN_Y	P60484	PTEN	P07948	LYN	Y27	L25Q	25	Missense	proximal	-2	no	1.661	3.229	EPSD	CCLE	1.526	Up-regulation
TK_Src_SrcB_LYN_Y	P60484	PTEN	P07948	LYN	Y46	R47W	47	Missense	proximal	1	no	2.264	0.738	EPSD	CCLE	1.526	Loss
TK_Src_SrcB_LYN_Y	P60484	PTEN	P07948	LYN	Y46	V53D	53	Missense	distal	7	no	2.264	2.237	EPSD	CCLE	1.526	Down-regulation
TK_Src_SrcB_LYN_Y	P60484	PTEN	P07948	LYN	Y240	F243V	243	Missense	distal	3	no	1.505	2.094	PhosphoSitePlus	CCLE	1.526	Gain
TK_Src_SrcB_LYN_Y	P14317	HCLS1	P07948	LYN	Y222	A217T	217	Missense	distal	-5	no	5.208	6.808	PhosphoSitePlus	CCLE	1.526	Up-regulation
TK_Src_SrcB_LYN_Y	Q9H792	PEAK1	P07948	LYN	Y387	E384K	384	Missense	distal	-3	no	1.850	1.332	EPSD	CCLE	1.526	Loss
TK_Src_SrcB_LYN_Y	P11802	CDK4	P07948	LYN	Y17	E11G	11	Missense	distal	-6	no	3.291	2.747	PhosphoSitePlus	CCLE	1.526	Down-regulation
TK_Src_SrcB_LYN_Y	P42768	WAS	P07948	LYN	Y102	W97Y	97	Missense	distal	-5	no	2.571	1.470	EPSD	CCLE	1.526	Loss
TK_Src_SrcB_LYN_Y	P42768	WAS	P07948	LYN	Y102	Y107C	107	Missense	distal	5	no	2.571	4.758	EPSD	CCLE	1.526	Up-regulation
TK_Src_SrcB_LYN_Y	P35354	PTGS2	P07948	LYN	Y120	A127V	127	Missense	distal	7	no	2.017	2.038	PhosphoSitePlus	CCLE	1.526	Up-regulation
AGC_RSK_RSKp90_RPS6KA3_ST	Q14934	NFATC4	P51812	RPS6KA3	S217	S221F	221	Missense	distal	4	no	1.806	1.887	EPSD	CCLE	1.803	Up-regulation
AGC_RSK_RSKp90_RPS6KA3_ST	Q14934	NFATC4	P51812	RPS6KA3	S221	S221F	221	Missense	central	0	yes	2.028	0.000	EPSD	CCLE	1.803	Loss
AGC_RSK_RSKp90_RPS6KA3_ST	Q14934	NFATC4	P51812	RPS6KA3	T226	S221F	221	Missense	distal	-5	no	2.154	2.021	EPSD	CCLE	1.803	Down-regulation
AGC_RSK_RSKp90_RPS6KA3_ST	Q99683	MAP3K5	P51812	RPS6KA3	S82	R78Q	78	Missense	distal	-4	no	2.365	2.199	EPSD	CCLE	1.803	Down-regulation
AGC_RSK_RSKp90_RPS6KA3_ST	Q99683	MAP3K5	P51812	RPS6KA3	S83	R78Q	78	Missense	distal	-5	no	4.412	4.050	PhosphoSitePlus;EPSD	CCLE	1.803	Down-regulation
AGC_RSK_RSKp90_RPS6KA3_ST	Q99683	MAP3K5	P51812	RPS6KA3	S719	S716N	716	Missense	distal	-3	no	2.810	2.693	EPSD	CCLE	1.803	Down-regulation
AGC_RSK_RSKp90_RPS6KA3_ST	Q92934	BAD	P51812	RPS6KA3	S25	S32L	32	Missense	distal	7	no	1.797	1.842	EPSD	CCLE	1.803	Gain
AGC_RSK_RSKp90_RPS6KA3_ST	Q92934	BAD	P51812	RPS6KA3	S74	H73Q	73	Missense	proximal	-1	no	1.804	1.815	EPSD	CCLE	1.803	Up-regulation
AGC_RSK_RSKp90_RPS6KA3_ST	Q92934	BAD	P51812	RPS6KA3	S74	R70W	70	Missense	distal	-4	no	1.804	1.614	EPSD	CCLE	1.803	Loss
AGC_RSK_RSKp90_RPS6KA3_ST	Q92934	BAD	P51812	RPS6KA3	S75	H73Q	73	Missense	proximal	-2	no	4.372	4.403	PhosphoSitePlus;EPSD	CCLE	1.803	Up-regulation
AGC_RSK_RSKp90_RPS6KA3_ST	Q92934	BAD	P51812	RPS6KA3	S75	R70W	70	Missense	distal	-5	no	4.372	3.990	PhosphoSitePlus;EPSD	CCLE	1.803	Down-regulation
AGC_RSK_RSKp90_RPS6KA3_ST	Q8IX03	WWC1	P51812	RPS6KA3	S33	T28R	28	Missense	distal	-5	no	3.708	4.072	EPSD	CCLE	1.803	Up-regulation
AGC_RSK_RSKp90_RPS6KA3_ST	Q8IX03	WWC1	P51812	RPS6KA3	S255	W260C	260	Missense	distal	5	no	1.978	1.988	EPSD	CCLE	1.803	Up-regulation
AGC_RSK_RSKp90_RPS6KA3_ST	Q8IX03	WWC1	P51812	RPS6KA3	S268	S268G	268	Missense	central	0	yes	1.826	0.000	EPSD	CCLE	1.803	Loss
AGC_RSK_RSKp90_RPS6KA3_ST	Q8IX03	WWC1	P51812	RPS6KA3	S270	S268G	268	Missense	proximal	-2	no	1.810	1.692	EPSD	CCLE	1.803	Loss
AGC_RSK_RSKp90_RPS6KA3_ST	Q8IX03	WWC1	P51812	RPS6KA3	S358	P359L	359	Missense	proximal	1	no	3.731	3.751	EPSD	CCLE	1.803	Up-regulation
AGC_RSK_RSKp90_RPS6KA3_ST	Q8IX03	WWC1	P51812	RPS6KA3	S437	M430I	430	Missense	distal	-7	no	1.936	1.939	EPSD	CCLE	1.803	Up-regulation
AGC_RSK_RSKp90_RPS6KA3_ST	P49841	GSK3B	P51812	RPS6KA3	S147	T152M	152	Missense	distal	5	no	3.392	3.367	EPSD	CCLE	1.803	Down-regulation
AGC_RSK_RSKp90_RPS6KA3_ST	Q9H6Z4	RANBP3	P51812	RPS6KA3	S221	V227L	227	Missense	distal	6	no	3.790	3.797	EPSD	CCLE	1.803	Up-regulation
AGC_RSK_RSKp90_RPS6KA3_ST	Q9H6Z4	RANBP3	P51812	RPS6KA3	S240	N242S	242	Missense	proximal	2	no	2.005	2.084	EPSD	CCLE	1.803	Up-regulation
AGC_RSK_RSKp90_RPS6KA3_ST	P07101	TH	P51812	RPS6KA3	S71	R68H	68	Missense	distal	-3	no	4.398	1.859	EPSD;PhosphoSitePlus	CCLE	1.803	Down-regulation
AGC_RSK_RSKp90_RPS6KA3_ST	P07101	TH	P51812	RPS6KA3	S71	R68C	68	Missense	distal	-3	no	4.398	1.787	EPSD;PhosphoSitePlus	CCLE	1.803	Loss
AGC_RSK_RSKp90_RPS6KA3_ST	P19525	EIF2AK2	P51812	RPS6KA3	S181	Y176H	176	Missense	distal	-5	no	1.851	1.859	EPSD	CCLE	1.803	Up-regulation
AGC_RSK_RSKp90_RPS6KA3_ST	P19525	EIF2AK2	P51812	RPS6KA3	S456	S462L	462	Missense	distal	6	no	3.709	3.657	EPSD	CCLE	1.803	Down-regulation
AGC_RSK_RSKp90_RPS6KA3_ST	P03372	ESR1	P51812	RPS6KA3	S236	A239D	239	Missense	distal	3	no	4.297	4.301	EPSD	CCLE	1.803	Up-regulation
AGC_RSK_RSKp90_RPS6KA3_ST	P67809	YBX1	P51812	RPS6KA3	T80	F85C	85	Missense	distal	5	no	1.873	1.845	EPSD	CCLE	1.803	Down-regulation
AGC_RSK_RSKp90_RPS6KA3_ST	P67809	YBX1	P51812	RPS6KA3	S102	S102I	102	Missense	central	0	yes	1.917	0.000	PhosphoSitePlus	CCLE	1.803	Loss
AGC_RSK_RSKp90_RPS6KA3_ST	P13796	LCP1	P51812	RPS6KA3	T503	R500I	500	Missense	distal	-3	no	2.317	-0.150	EPSD	CCLE	1.803	Loss
AGC_RSK_RSKp90_RPS6KA3_ST	Q9UL17	TBX21	P51812	RPS6KA3	S394	A401S	401	Missense	distal	7	no	3.886	3.867	EPSD	CCLE	1.803	Down-regulation
AGC_RSK_RSKp90_RPS6KA3_ST	Q9UL17	TBX21	P51812	RPS6KA3	S403	A401S	401	Missense	proximal	-2	no	3.868	3.906	EPSD	CCLE	1.803	Up-regulation
AGC_RSK_RSKp90_RPS6KA3_ST	Q9UL17	TBX21	P51812	RPS6KA3	S403	F408L	408	Missense	distal	5	no	3.868	3.848	EPSD	CCLE	1.803	Down-regulation
AGC_RSK_RSKp90_RPS6KA3_ST	P53355	DAPK1	P51812	RPS6KA3	S57	S52N	52	Missense	distal	-5	no	3.715	3.711	EPSD	CCLE	1.803	Down-regulation
AGC_RSK_RSKp90_RPS6KA3_ST	P53355	DAPK1	P51812	RPS6KA3	S321	F322Y	322	Missense	proximal	1	no	1.807	1.786	EPSD	CCLE	1.803	Loss
AGC_RSK_RSKp90_RPS6KA3_ST	P53355	DAPK1	P51812	RPS6KA3	S329	F322Y	322	Missense	distal	-7	no	1.804	1.798	EPSD	CCLE	1.803	Loss
AGC_RSK_RSKp90_RPS6KA3_ST	P53355	DAPK1	P51812	RPS6KA3	S762	V758L	758	Missense	distal	-4	no	3.212	3.241	EPSD	CCLE	1.803	Up-regulation
AGC_RSK_RSKp90_RPS6KA3_ST	Q16821	PPP1R3A	P51812	RPS6KA3	S48	L54M	54	Missense	distal	6	no	1.929	1.940	EPSD	CCLE	1.803	Up-regulation
AGC_RSK_RSKp90_RPS6KA3_ST	Q16821	PPP1R3A	P51812	RPS6KA3	S49	L54M	54	Missense	distal	5	no	1.834	1.805	EPSD	CCLE	1.803	Down-regulation
AGC_RSK_RSKp90_RPS6KA3_ST	Q16821	PPP1R3A	P51812	RPS6KA3	S65	T61S	61	Missense	distal	-4	no	4.168	4.288	EPSD;PhosphoSitePlus	CCLE	1.803	Up-regulation
AGC_RSK_RSKp90_RPS6KA3_ST	P18848	ATF4	P51812	RPS6KA3	S326	L327P	327	Missense	proximal	1	no	3.725	3.705	EPSD	CCLE	1.803	Down-regulation
AGC_RSK_RSKp90_RPS6KA3_ST	P48764	SLC9A3	P51812	RPS6KA3	S555	S561F	561	Missense	distal	6	no	3.739	3.670	EPSD	CCLE	1.803	Down-regulation
AGC_RSK_RSKp90_RPS6KA3_ST	P48764	SLC9A3	P51812	RPS6KA3	S563	S561F	561	Missense	proximal	-2	no	3.937	3.700	EPSD	CCLE	1.803	Down-regulation
AGC_RSK_RSKp90_RPS6KA3_ST	P48764	SLC9A3	P51812	RPS6KA3	S808	S807N	807	Missense	proximal	-1	no	4.040	4.012	EPSD	CCLE	1.803	Down-regulation
AGC_RSK_RSKp90_RPS6KA3_ST	P48764	SLC9A3	P51812	RPS6KA3	S810	S807N	807	Missense	distal	-3	no	2.158	2.041	EPSD	CCLE	1.803	Down-regulation
AGC_RSK_RSKp90_RPS6KA3_ST	P48764	SLC9A3	P51812	RPS6KA3	S831	A826T	826	Missense	distal	-5	no	1.813	1.762	EPSD	CCLE	1.803	Loss
AGC_RSK_RSKp90_RPS6KA3_ST	Q96RK0	CIC	P51812	RPS6KA3	S12	H5Y	5	Missense	distal	-7	no	1.931	1.934	EPSD	CCLE	1.803	Up-regulation
AGC_RSK_RSKp90_RPS6KA3_ST	Q96RK0	CIC	P51812	RPS6KA3	S277	T284A	284	Missense	distal	7	no	4.091	4.061	EPSD	CCLE	1.803	Down-regulation
AGC_RSK_RSKp90_RPS6KA3_ST	Q96RK0	CIC	P51812	RPS6KA3	S279	T284A	284	Missense	distal	5	no	2.543	2.495	EPSD	CCLE	1.803	Down-regulation
AGC_RSK_RSKp90_RPS6KA3_ST	Q96RK0	CIC	P51812	RPS6KA3	S285	T284A	284	Missense	proximal	-1	no	1.803	1.831	EPSD	CCLE	1.803	Up-regulation
AGC_RSK_RSKp90_RPS6KA3_ST	Q96RK0	CIC	P51812	RPS6KA3	S334	R340S	340	Missense	distal	6	no	2.036	2.018	EPSD	CCLE	1.803	Down-regulation
AGC_RSK_RSKp90_RPS6KA3_ST	Q96RK0	CIC	P51812	RPS6KA3	T343	R340S	340	Missense	distal	-3	no	2.613	0.606	EPSD	CCLE	1.803	Loss
AGC_RSK_RSKp90_RPS6KA3_ST	Q96RK0	CIC	P51812	RPS6KA3	S356	P352L	352	Missense	distal	-4	no	4.102	4.066	EPSD	CCLE	1.803	Down-regulation
AGC_RSK_RSKp90_RPS6KA3_ST	Q96RK0	CIC	P51812	RPS6KA3	S356	P352R	352	Missense	distal	-4	no	4.102	4.254	EPSD	CCLE	1.803	Up-regulation
AGC_RSK_RSKp90_RPS6KA3_ST	Q96RK0	CIC	P51812	RPS6KA3	S424	A429V	429	Missense	distal	5	no	1.837	1.890	EPSD	CCLE	1.803	Up-regulation
AGC_RSK_RSKp90_RPS6KA3_ST	Q96RK0	CIC	P51812	RPS6KA3	S426	A429V	429	Missense	distal	3	no	1.932	1.937	EPSD	CCLE	1.803	Up-regulation
AGC_RSK_RSKp90_RPS6KA3_ST	Q96RK0	CIC	P51812	RPS6KA3	S431	A429V	429	Missense	proximal	-2	no	3.621	3.450	EPSD	CCLE	1.803	Down-regulation
AGC_RSK_RSKp90_RPS6KA3_ST	Q96RK0	CIC	P51812	RPS6KA3	S902	P897T	897	Missense	distal	-5	no	1.899	1.858	EPSD	CCLE	1.803	Down-regulation
AGC_RSK_RSKp90_RPS6KA3_ST	P05198	EIF2S1	P51812	RPS6KA3	S91	P92S	92	Missense	proximal	1	no	3.952	3.913	EPSD	CCLE	1.803	Down-regulation
AGC_RSK_RSKp90_RPS6KA3_ST	P05198	EIF2S1	P51812	RPS6KA3	S91	K97R	97	Missense	distal	6	no	3.952	3.996	EPSD	CCLE	1.803	Up-regulation
AGC_RSK_RSKp90_RPS6KA3_ST	P05198	EIF2S1	P51812	RPS6KA3	S91	C98S	98	Missense	distal	7	no	3.952	3.908	EPSD	CCLE	1.803	Down-regulation
CK1_TTBK_TTBK2_ST	Q7L0J3	SV2A	Q6IQ55	TTBK2	S42	S47P	47	Missense	distal	5	no	7.526	6.092	EPSD;PhosphoSitePlus	CCLE	3.341	Down-regulation
CK1_TTBK_TTBK2_ST	Q7L0J3	SV2A	Q6IQ55	TTBK2	S45	E52G	52	Missense	distal	7	no	7.586	7.666	EPSD;PhosphoSitePlus	CCLE	3.341	Up-regulation
CK1_TTBK_TTBK2_ST	Q7L0J3	SV2A	Q6IQ55	TTBK2	S45	S47P	47	Missense	proximal	2	no	7.586	7.711	EPSD;PhosphoSitePlus	CCLE	3.341	Up-regulation
CK1_TTBK_TTBK2_ST	Q7L0J3	SV2A	Q6IQ55	TTBK2	S47	D53E	53	Missense	distal	6	no	7.658	7.697	PhosphoSitePlus;EPSD	CCLE	3.341	Up-regulation
CK1_TTBK_TTBK2_ST	Q7L0J3	SV2A	Q6IQ55	TTBK2	S47	E52G	52	Missense	distal	5	no	7.658	6.504	PhosphoSitePlus;EPSD	CCLE	3.341	Down-regulation
CK1_TTBK_TTBK2_ST	Q7L0J3	SV2A	Q6IQ55	TTBK2	S47	S47P	47	Missense	central	0	yes	7.658	0.000	PhosphoSitePlus;EPSD	CCLE	3.341	Loss
TK_Tec_BTK_Y	P16885	PLCG2	Q06187	BTK	Y759	I765V	765	Missense	distal	6	no	3.275	3.151	EPSD;PhosphoSitePlus	CCLE	1.787	Down-regulation
TK_Tec_BTK_Y	P16885	PLCG2	Q06187	BTK	Y1197	Q1202R	1202	Missense	distal	5	no	3.522	3.581	EPSD	CCLE	1.787	Up-regulation
TK_Tec_BTK_Y	P58753	TIRAP	Q06187	BTK	Y106	Q101E	101	Missense	distal	-5	no	2.946	2.875	PhosphoSitePlus;EPSD	CCLE	1.787	Down-regulation
TK_Tec_BTK_Y	P58753	TIRAP	Q06187	BTK	Y187	S183N	183	Missense	distal	-4	no	3.246	3.245	EPSD;PhosphoSitePlus	CCLE	1.787	Down-regulation
TK_Tec_BTK_Y	P58753	TIRAP	Q06187	BTK	Y187	R184T	184	Missense	distal	-3	no	3.246	3.189	EPSD;PhosphoSitePlus	CCLE	1.787	Down-regulation
TKL_IRAK_IRAK4_ST	Q96FA3	PELI1	Q9NWZ3	IRAK4	T86	E90K	90	Missense	distal	4	no	195.317	207.188	EPSD;PhosphoSitePlus	CCLE	132.233	Up-regulation
TKL_IRAK_IRAK4_ST	Q9NWZ3	IRAK4	Q9NWZ3	IRAK4	T208	T209A	209	Missense	proximal	1	no	238.403	226.141	PhosphoSitePlus;EPSD	CCLE	132.233	Down-regulation
TKL_IRAK_IRAK4_ST	Q9NWZ3	IRAK4	Q9NWZ3	IRAK4	T209	T209A	209	Missense	central	0	yes	179.147	0.000	EPSD;PhosphoSitePlus	CCLE	132.233	Loss
TKL_IRAK_IRAK4_ST	P14598	NCF1	Q9NWZ3	IRAK4	S320	R326H	326	Missense	distal	6	no	178.601	131.439	EPSD;PhosphoSitePlus	CCLE	132.233	Loss
TKL_IRAK_IRAK4_ST	P14598	NCF1	Q9NWZ3	IRAK4	S348	R354L	354	Missense	distal	6	no	178.847	135.367	PhosphoSitePlus;EPSD	CCLE	132.233	Down-regulation
TKL_IRAK_IRAK4_ST	P14598	NCF1	Q9NWZ3	IRAK4	T356	R354L	354	Missense	proximal	-2	no	159.483	155.405	EPSD;PhosphoSitePlus	CCLE	132.233	Down-regulation
TKL_IRAK_IRAK4_ST	P14598	NCF1	Q9NWZ3	IRAK4	T356	Q357H	357	Missense	proximal	1	no	159.483	142.079	EPSD;PhosphoSitePlus	CCLE	132.233	Down-regulation
TKL_IRAK_IRAK4_ST	P14598	NCF1	Q9NWZ3	IRAK4	S359	R354L	354	Missense	distal	-5	no	173.390	164.460	EPSD;PhosphoSitePlus	CCLE	132.233	Down-regulation
TKL_IRAK_IRAK4_ST	P14598	NCF1	Q9NWZ3	IRAK4	S359	Q357H	357	Missense	proximal	-2	no	173.390	165.173	EPSD;PhosphoSitePlus	CCLE	132.233	Down-regulation
CK1_TTBK_TTBK1_ST	P10636	MAPT	Q5TCY1	TTBK1	S228	D221Y	221	Missense	distal	-7	no	11.654	10.537	EPSD	CCLE	7.699	Down-regulation
CK1_TTBK_TTBK1_ST	P10636	MAPT	Q5TCY1	TTBK1	S228	P234S	234	Missense	distal	6	no	11.654	13.236	EPSD	CCLE	7.699	Up-regulation
CK1_TTBK_TTBK1_ST	P10636	MAPT	Q5TCY1	TTBK1	S238	P234S	234	Missense	distal	-4	no	11.337	11.255	EPSD	CCLE	7.699	Down-regulation
CK1_TTBK_TTBK1_ST	P10636	MAPT	Q5TCY1	TTBK1	S238	D242H	242	Missense	distal	4	no	11.337	10.856	EPSD	CCLE	7.699	Down-regulation
CK1_TTBK_TTBK1_ST	P10636	MAPT	Q5TCY1	TTBK1	S411	K405R	405	Missense	distal	-6	no	10.521	9.834	EPSD	CCLE	7.699	Down-regulation
CK1_TTBK_TTBK1_ST	P10636	MAPT	Q5TCY1	TTBK1	S508	R511H	511	Missense	distal	3	no	11.808	11.663	EPSD	CCLE	7.699	Down-regulation
CK1_TTBK_TTBK1_ST	P10636	MAPT	Q5TCY1	TTBK1	S512	R511H	511	Missense	proximal	-1	no	11.085	10.990	EPSD	CCLE	7.699	Down-regulation
CK1_TTBK_TTBK1_ST	P10636	MAPT	Q5TCY1	TTBK1	S512	G518S	518	Missense	distal	6	no	11.085	12.780	EPSD	CCLE	7.699	Up-regulation
CK1_TTBK_TTBK1_ST	P10636	MAPT	Q5TCY1	TTBK1	S515	R511H	511	Missense	distal	-4	no	14.725	14.695	EPSD	CCLE	7.699	Down-regulation
CK1_TTBK_TTBK1_ST	P10636	MAPT	Q5TCY1	TTBK1	S515	G518S	518	Missense	distal	3	no	14.725	14.438	EPSD	CCLE	7.699	Down-regulation
CK1_TTBK_TTBK1_ST	P10636	MAPT	Q5TCY1	TTBK1	S516	R511H	511	Missense	distal	-5	no	14.085	14.100	EPSD	CCLE	7.699	Up-regulation
CK1_TTBK_TTBK1_ST	P10636	MAPT	Q5TCY1	TTBK1	S516	G518S	518	Missense	proximal	2	no	14.085	14.147	EPSD	CCLE	7.699	Up-regulation
CK1_TTBK_TTBK1_ST	P10636	MAPT	Q5TCY1	TTBK1	S519	G518S	518	Missense	proximal	-1	no	19.267	19.656	EPSD	CCLE	7.699	Up-regulation
CK1_TTBK_TTBK1_ST	P10636	MAPT	Q5TCY1	TTBK1	S519	R526L	526	Missense	distal	7	no	19.267	19.348	EPSD	CCLE	7.699	Up-regulation
CK1_TTBK_TTBK1_ST	P10636	MAPT	Q5TCY1	TTBK1	T522	G518S	518	Missense	distal	-4	no	12.073	11.963	EPSD	CCLE	7.699	Down-regulation
CK1_TTBK_TTBK1_ST	P10636	MAPT	Q5TCY1	TTBK1	T522	R526L	526	Missense	distal	4	no	12.073	12.608	EPSD	CCLE	7.699	Up-regulation
CK1_TTBK_TTBK1_ST	P10636	MAPT	Q5TCY1	TTBK1	S525	G518S	518	Missense	distal	-7	no	7.425	8.988	EPSD	CCLE	7.699	Gain
CK1_TTBK_TTBK1_ST	P10636	MAPT	Q5TCY1	TTBK1	S525	R526L	526	Missense	proximal	1	no	7.425	10.771	EPSD	CCLE	7.699	Gain
CK1_TTBK_TTBK1_ST	P10636	MAPT	Q5TCY1	TTBK1	T529	R526L	526	Missense	distal	-3	no	11.833	11.844	EPSD	CCLE	7.699	Up-regulation
CK1_TTBK_TTBK1_ST	P10636	MAPT	Q5TCY1	TTBK1	S552	R559H	559	Missense	distal	7	no	11.750	12.031	EPSD	CCLE	7.699	Up-regulation
CK1_TTBK_TTBK1_ST	P10636	MAPT	Q5TCY1	TTBK1	S555	R559H	559	Missense	distal	4	no	8.530	8.774	EPSD	CCLE	7.699	Up-regulation
CK1_TTBK_TTBK1_ST	P10636	MAPT	Q5TCY1	TTBK1	S713	G706V	706	Missense	distal	-7	no	12.492	13.279	EPSD	CCLE	7.699	Up-regulation
CK1_TTBK_TTBK1_ST	P10636	MAPT	Q5TCY1	TTBK1	S713	S717C	717	Missense	distal	4	no	12.492	12.170	EPSD	CCLE	7.699	Down-regulation
CK1_TTBK_TTBK1_ST	P10636	MAPT	Q5TCY1	TTBK1	S721	S717C	717	Missense	distal	-4	no	14.656	14.737	EPSD	CCLE	7.699	Up-regulation
CK1_TTBK_TTBK1_ST	P10636	MAPT	Q5TCY1	TTBK1	S721	S721C	721	Missense	central	0	yes	14.656	0.000	EPSD	CCLE	7.699	Loss
CK1_TTBK_TTBK1_ST	P10636	MAPT	Q5TCY1	TTBK1	S721	H724R	724	Missense	distal	3	no	14.656	14.801	EPSD	CCLE	7.699	Up-regulation
CK1_TTBK_TTBK1_ST	P10636	MAPT	Q5TCY1	TTBK1	S739	Q741K	741	Missense	proximal	2	no	11.793	11.808	EPSD	CCLE	7.699	Up-regulation
CK1_TTBK_TTBK1_ST	P10636	MAPT	Q5TCY1	TTBK1	T744	Q741K	741	Missense	distal	-3	no	10.882	10.868	EPSD	CCLE	7.699	Down-regulation
TKL_MLK_ZAK_MAP3K20_ST	O96017	CHEK2	Q9NYL2	MAP3K20	S435	S435L	435	Missense	central	0	yes	3.094	0.000	EPSD	CCLE	2.674	Loss
TKL_MLK_ZAK_MAP3K20_ST	O96017	CHEK2	Q9NYL2	MAP3K20	T441	S435L	435	Missense	distal	-6	no	3.549	3.469	EPSD	CCLE	2.674	Down-regulation
TKL_MLK_ZAK_MAP3K20_ST	O96017	CHEK2	Q9NYL2	MAP3K20	S505	L512I	512	Missense	distal	7	no	3.271	3.159	EPSD	CCLE	2.674	Down-regulation
TKL_MLK_ZAK_MAP3K20_ST	O96017	CHEK2	Q9NYL2	MAP3K20	S516	R521Q	521	Missense	distal	5	no	2.827	2.687	EPSD	CCLE	2.674	Down-regulation
TKL_MLK_ZAK_MAP3K20_ST	O96017	CHEK2	Q9NYL2	MAP3K20	S516	L512I	512	Missense	distal	-4	no	2.827	2.688	EPSD	CCLE	2.674	Down-regulation
TKL_MLK_ZAK_MAP3K20_ST	O96017	CHEK2	Q9NYL2	MAP3K20	S518	R521Q	521	Missense	distal	3	no	3.168	2.806	EPSD	CCLE	2.674	Down-regulation
TKL_MLK_ZAK_MAP3K20_ST	O96017	CHEK2	Q9NYL2	MAP3K20	S518	L512I	512	Missense	distal	-6	no	3.168	2.628	EPSD	CCLE	2.674	Loss
CAMK_CAMKL_NuaK_NUAK1_ST	P10636	MAPT	O60285	NUAK1	S214	D221Y	221	Missense	distal	7	no	5.065	5.068	EPSD	CCLE	4.034	Up-regulation
CAMK_CAMKL_NuaK_NUAK1_ST	P10636	MAPT	O60285	NUAK1	S438	V442I	442	Missense	distal	4	no	4.184	3.381	EPSD	CCLE	4.034	Loss
CAMK_CAMKL_NuaK_NUAK1_ST	P10636	MAPT	O60285	NUAK1	S531	R526L	526	Missense	distal	-5	no	4.912	5.101	EPSD	CCLE	4.034	Up-regulation
CAMK_CAMKL_NuaK_NUAK1_ST	P10636	MAPT	O60285	NUAK1	S579	K574N	574	Missense	distal	-5	no	9.984	9.974	EPSD	CCLE	4.034	Down-regulation
CAMK_CAMKL_NuaK_NUAK1_ST	P10636	MAPT	O60285	NUAK1	S637	D631E	631	Missense	distal	-6	no	3.934	4.057	EPSD	CCLE	4.034	Gain
CAMK_CAMKL_NuaK_NUAK1_ST	O14974	PPP1R12A	O60285	NUAK1	S472	S477A	477	Missense	distal	5	no	9.804	9.842	PhosphoSitePlus;EPSD	CCLE	4.034	Up-regulation
CAMK_CAMKL_NuaK_NUAK1_ST	P55212	CASP6	O60285	NUAK1	S3	G10R	10	Missense	distal	7	no	4.590	4.663	EPSD	CCLE	4.034	Up-regulation
CAMK_CAMKL_NuaK_NUAK1_ST	O95835	LATS1	O60285	NUAK1	S177	R174C	174	Missense	distal	-3	no	5.066	3.388	EPSD	CCLE	4.034	Loss
CAMK_CAMKL_NuaK_NUAK1_ST	O95835	LATS1	O60285	NUAK1	S387	G392R	392	Missense	distal	5	no	4.540	4.447	EPSD	CCLE	4.034	Down-regulation
Other_ULK_ULK_ULK2_ST	O15027	SEC16A	Q8IYT8	ULK2	S179	A182S	182	Missense	distal	3	no	4.491	4.316	EPSD	CCLE	3.097	Down-regulation
Other_ULK_ULK_ULK2_ST	O15027	SEC16A	Q8IYT8	ULK2	T337	T337I	337	Missense	central	0	yes	3.733	0.000	EPSD	CCLE	3.097	Loss
Other_ULK_ULK_ULK2_ST	O15027	SEC16A	Q8IYT8	ULK2	S391	P392L	392	Missense	proximal	1	no	3.669	4.589	EPSD	CCLE	3.097	Up-regulation
Other_ULK_ULK_ULK2_ST	O15027	SEC16A	Q8IYT8	ULK2	S391	D389N	389	Missense	proximal	-2	no	3.669	3.660	EPSD	CCLE	3.097	Down-regulation
Other_ULK_ULK_ULK2_ST	O15027	SEC16A	Q8IYT8	ULK2	S431	S428I	428	Missense	distal	-3	no	1.995	3.147	EPSD	CCLE	3.097	Gain
Other_ULK_ULK_ULK2_ST	O15027	SEC16A	Q8IYT8	ULK2	S432	S428I	428	Missense	distal	-4	no	3.203	3.360	EPSD	CCLE	3.097	Up-regulation
Other_ULK_ULK_ULK2_ST	O15027	SEC16A	Q8IYT8	ULK2	S1044	P1043L	1043	Missense	proximal	-1	no	3.054	3.375	EPSD	CCLE	3.097	Gain
Other_ULK_ULK_ULK2_ST	O15027	SEC16A	Q8IYT8	ULK2	S1175	S1169N	1169	Missense	distal	-6	no	2.820	3.103	EPSD	CCLE	3.097	Gain
Other_ULK_ULK_ULK2_ST	O15027	SEC16A	Q8IYT8	ULK2	S1731	L1737S	1737	Missense	distal	6	no	3.350	3.381	EPSD	CCLE	3.097	Up-regulation
Other_ULK_ULK_ULK2_ST	O15027	SEC16A	Q8IYT8	ULK2	S1844	S1844R	1844	Missense	central	0	yes	3.686	0.000	EPSD	CCLE	3.097	Loss
Other_ULK_ULK_ULK2_ST	O15027	SEC16A	Q8IYT8	ULK2	S1903	T1898K	1898	Missense	distal	-5	no	3.218	3.278	EPSD	CCLE	3.097	Up-regulation
Other_ULK_ULK_ULK2_ST	O15027	SEC16A	Q8IYT8	ULK2	S1981	A1974T	1974	Missense	distal	-7	no	3.951	3.953	EPSD	CCLE	3.097	Up-regulation